ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bags8h11 |
|---|---|
| Clone Library Name | barley_pub |
>KTNB1_ARATH (Q8H0T9) Katanin p80 WD40-containing subunit B1 homolog 1| Length = 837 Score = 265 bits (678), Expect = 6e-71 Identities = 119/168 (70%), Positives = 147/168 (87%) Frame = +3 Query: 96 MATKRAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTS 275 M TKRAYKLQEFVAH++ V C K G+++SR L+TGGED KVNLWA+GKP A+LSL G +S Sbjct: 1 MTTKRAYKLQEFVAHSAAVNCLKIGRKSSRVLVTGGEDHKVNLWAIGKPNAILSLYGHSS 60 Query: 276 PVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGS 455 ++S++FD+SEV++ AGAASGTIK+WD+EEAK+VRT TGHRSNC S+D HPFG+FFASGS Sbjct: 61 GIDSVTFDASEVLVAAGAASGTIKLWDLEEAKIVRTLTGHRSNCISVDFHPFGEFFASGS 120 Query: 456 SDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 DTN+KIWD+RKK CIHTY+GHT ++VLRFTPDGRW+VSGG D+ VK Sbjct: 121 LDTNLKIWDIRKKGCIHTYKGHTRGVNVLRFTPDGRWVVSGGEDNIVK 168 Score = 73.9 bits (180), Expect = 3e-13 Identities = 37/132 (28%), Positives = 60/132 (45%) Frame = +3 Query: 195 TGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKV 374 +G D + +W + K + + G T V L F + +G +K+WD+ K+ Sbjct: 118 SGSLDTNLKIWDIRKKGCIHTYKGHTRGVNVLRFTPDGRWVVSGGEDNIVKVWDLTAGKL 177 Query: 375 VRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTP 554 + F H SLD HP A+GS+D +K WD+ I + T + L F P Sbjct: 178 LTEFKSHEGQIQSLDFHPHEFLLATGSADRTVKFWDLETFELIGSGGPETAGVRCLSFNP 237 Query: 555 DGRWIVSGGADS 590 DG+ ++ G +S Sbjct: 238 DGKTVLCGLQES 249 Score = 49.7 bits (117), Expect = 6e-06 Identities = 29/127 (22%), Positives = 55/127 (43%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 + + H V +F R +++GGED V +W + + ++SL F Sbjct: 136 IHTYKGHTRGVNVLRFTP-DGRWVVSGGEDNIVKVWDLTAGKLLTEFKSHEGQIQSLDFH 194 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 E ++ G+A T+K WD+E +++ + + L +P G G + ++KI+ Sbjct: 195 PHEFLLATGSADRTVKFWDLETFELIGSGGPETAGVRCLSFNPDGKTVLCGLQE-SLKIF 253 Query: 480 DMRKKRC 500 RC Sbjct: 254 SWEPIRC 260
>KTNB1_STRPU (O61585) Katanin p80 WD40-containing subunit B1 (Katanin p80| subunit B1) (p80 katanin) Length = 690 Score = 221 bits (564), Expect = 1e-57 Identities = 95/168 (56%), Positives = 139/168 (82%) Frame = +3 Query: 96 MATKRAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTS 275 MATKRA+KLQE VAH+S+V C G + R ++TGGED+KVNLWAVGK ++SLSG TS Sbjct: 1 MATKRAWKLQELVAHSSNVNCLALGPMSGRVMVTGGEDKKVNLWAVGKQNCIISLSGHTS 60 Query: 276 PVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGS 455 PV+S+ F+SSE ++ AG+ SGT+KI+D+E AK+VRT TGHR++ +D HPFG+F ASGS Sbjct: 61 PVDSVKFNSSEELVVAGSQSGTMKIYDLEPAKIVRTLTGHRNSIRCMDFHPFGEFVASGS 120 Query: 456 SDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 +DTN+K+WD+R+K CI+TY+GH+ ++++++F+PDG+W+V+ D+++K Sbjct: 121 TDTNVKLWDVRRKGCIYTYKGHSDQVNMIKFSPDGKWLVTASEDTTIK 168 Score = 69.7 bits (169), Expect = 6e-12 Identities = 39/172 (22%), Positives = 69/172 (40%), Gaps = 6/172 (3%) Frame = +3 Query: 90 SRMATKRAYKLQE------FVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAV 251 S+ T + Y L+ H + + C F + +G D V LW V + + Sbjct: 78 SQSGTMKIYDLEPAKIVRTLTGHRNSIRCMDFHP-FGEFVASGSTDTNVKLWDVRRKGCI 136 Query: 252 LSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPF 431 + G + V + F + + TIK+WD+ K+ + F H ++ HP Sbjct: 137 YTYKGHSDQVNMIKFSPDGKWLVTASEDTTIKLWDLTMGKLFQEFKNHTGGVTGIEFHPN 196 Query: 432 GDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGAD 587 ASGSSD ++ WD+ + + + + + F PDG ++ D Sbjct: 197 EFLLASGSSDRTVQFWDLETFQLVSSTSPGASAVRSISFHPDGSYLFCSSQD 248
>KTNB1_HUMAN (Q9BVA0) Katanin p80 WD40-containing subunit B1 (Katanin p80| subunit B1) (p80 katanin) Length = 655 Score = 199 bits (505), Expect = 7e-51 Identities = 87/168 (51%), Positives = 126/168 (75%) Frame = +3 Query: 96 MATKRAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTS 275 + TK A+KLQE VAHAS+V+ GK + R L TGG+D +VNLW++ KP ++SL+G TS Sbjct: 5 VVTKTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTS 64 Query: 276 PVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGS 455 PVES+ ++ E +I AG+ SG+I++WD+E AK++RT GH++N SLD HP+G+F ASGS Sbjct: 65 PVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGS 124 Query: 456 SDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 DTN+K+WD+R+K C+ Y+GH+ + LRF+PDG+W+ S D +VK Sbjct: 125 QDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVK 172 Score = 80.1 bits (196), Expect = 4e-15 Identities = 39/132 (29%), Positives = 63/132 (47%) Frame = +3 Query: 195 TGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKV 374 +G +D + LW + + V G + V L F + + A T+K+WD+ K+ Sbjct: 122 SGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKM 181 Query: 375 VRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTP 554 + F GH ++ HP ASGSSD ++ WD+ K + + +G G + + F P Sbjct: 182 MSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNP 241 Query: 555 DGRWIVSGGADS 590 DG + SG DS Sbjct: 242 DGCCLYSGCQDS 253 Score = 59.3 bits (142), Expect = 8e-09 Identities = 35/140 (25%), Positives = 64/140 (45%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMI 317 H+ V C +F + L + +D V LW + + G T PV + F +E ++ Sbjct: 146 HSQAVRCLRFSP-DGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLL 204 Query: 318 GAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKR 497 +G++ TI+ WD+E+ +VV G S+ +P G SG D +++++ +R Sbjct: 205 ASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQD-SLRVYGWEPER 263 Query: 498 CIHTYQGHTGRIDVLRFTPD 557 C + G++ L D Sbjct: 264 CFDVVLVNWGKVADLAICND 283
>KTNB1_MOUSE (Q8BG40) Katanin p80 WD40-containing subunit B1 (Katanin p80| subunit B1) (p80 katanin) Length = 658 Score = 199 bits (505), Expect = 7e-51 Identities = 87/168 (51%), Positives = 126/168 (75%) Frame = +3 Query: 96 MATKRAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTS 275 + TK A+KLQE VAHAS+V+ GK + R L TGG+D +VNLW++ KP ++SL+G TS Sbjct: 5 VVTKTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTS 64 Query: 276 PVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGS 455 PVES+ ++ E +I AG+ SG+I++WD+E AK++RT GH++N SLD HP+G+F ASGS Sbjct: 65 PVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGS 124 Query: 456 SDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 DTN+K+WD+R+K C+ Y+GH+ + LRF+PDG+W+ S D +VK Sbjct: 125 QDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVK 172 Score = 80.1 bits (196), Expect = 4e-15 Identities = 39/132 (29%), Positives = 63/132 (47%) Frame = +3 Query: 195 TGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKV 374 +G +D + LW + + V G + V L F + + A T+K+WD+ K+ Sbjct: 122 SGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKM 181 Query: 375 VRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTP 554 + F GH ++ HP ASGSSD ++ WD+ K + + +G G + + F P Sbjct: 182 MSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNP 241 Query: 555 DGRWIVSGGADS 590 DG + SG DS Sbjct: 242 DGCCLYSGCQDS 253 Score = 59.3 bits (142), Expect = 8e-09 Identities = 35/140 (25%), Positives = 64/140 (45%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMI 317 H+ V C +F + L + +D V LW + + G T PV + F +E ++ Sbjct: 146 HSQAVRCLRFSP-DGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLL 204 Query: 318 GAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKR 497 +G++ TI+ WD+E+ +VV G S+ +P G SG D +++++ +R Sbjct: 205 ASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQD-SLRVYGWEPER 263 Query: 498 CIHTYQGHTGRIDVLRFTPD 557 C + G++ L D Sbjct: 264 CFDVVLVNWGKVADLAICND 283
>KTNB1_BRARE (Q7ZUV2) Katanin p80 WD40-containing subunit B1 homolog| Length = 694 Score = 186 bits (472), Expect = 4e-47 Identities = 82/166 (49%), Positives = 122/166 (73%) Frame = +3 Query: 102 TKRAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPV 281 T ++KLQE VAH+S+V+ GK + R L TGGED +VN+WAV KP ++SL+G TS V Sbjct: 7 TITSWKLQEIVAHSSNVSSLVLGKSSGRLLATGGEDCRVNIWAVSKPNCIMSLTGHTSAV 66 Query: 282 ESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSD 461 + F+SSE + AG+ SG++++WD+E AK++RT GH+++ +SLD HP G++ ASGS D Sbjct: 67 GCIQFNSSEERVVAGSLSGSLRLWDLEAAKILRTLMGHKASISSLDFHPMGEYLASGSVD 126 Query: 462 TNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 +N+K+WD+R+K C+ Y+GHT + L F+PDG+W+ S DS+VK Sbjct: 127 SNIKLWDVRRKGCVFRYKGHTQAVRCLAFSPDGKWLASASDDSTVK 172 Score = 85.9 bits (211), Expect = 8e-17 Identities = 45/157 (28%), Positives = 74/157 (47%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 L+ + H + ++ F L +G D + LW V + V G T V L+F Sbjct: 98 LRTLMGHKASISSLDFHPM-GEYLASGSVDSNIKLWDVRRKGCVFRYKGHTQAVRCLAFS 156 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 + + + T+K+WD+ K++ FT H S + HP ASGS+D +K+W Sbjct: 157 PDGKWLASASDDSTVKLWDLIAGKMITEFTSHTSAVNVVQFHPNEYLLASGSADRTVKLW 216 Query: 480 DMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADS 590 D+ K I + +G TG + + F PDG + SG ++ Sbjct: 217 DLEKFNMIGSSEGETGVVRSVLFNPDGSCLYSGSENT 253
>KTNB1_CHICK (Q5ZIU8) Katanin p80 WD40-containing subunit B1 (Katanin p80| subunit B1) (p80 katanin) Length = 657 Score = 180 bits (457), Expect = 2e-45 Identities = 84/172 (48%), Positives = 121/172 (70%) Frame = +3 Query: 84 LPSRMATKRAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLS 263 + + + TK A+KLQE VAH+S+V+ GK T R L TGG+D +VN+W+V K L+ Sbjct: 1 MAAAVVTKTAWKLQEIVAHSSNVSSLVLGKSTGRLLATGGDDCQVNVWSV-KAQLRHELT 59 Query: 264 GLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFF 443 G T+P+ESL + E +I AG+ SG+I++WD+E AK++RT GH++N SLD HP+G F Sbjct: 60 GHTTPIESLQISAKEELIVAGSQSGSIRVWDLEAAKILRTLLGHKANICSLDFHPYGSFV 119 Query: 444 ASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 ASGS DT++K+WD+R+K CI Y+ HT + LRF+PDG+W+ S D +VK Sbjct: 120 ASGSLDTDIKLWDVRRKGCIFKYKSHTQAVRCLRFSPDGKWLASAADDHTVK 171 Score = 74.7 bits (182), Expect = 2e-13 Identities = 42/157 (26%), Positives = 68/157 (43%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 L+ + H +++ F S + +G D + LW V + + T V L F Sbjct: 97 LRTLLGHKANICSLDFHPYGS-FVASGSLDTDIKLWDVRRKGCIFKYKSHTQAVRCLRFS 155 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 + + A T+K+WD+ KV+ FTGH ++ HP ASGSSD ++ W Sbjct: 156 PDGKWLASAADDHTVKLWDLTAGKVMFEFTGHSGPVNVVEFHPSEYLLASGSSDRTIRFW 215 Query: 480 DMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADS 590 D+ K + + + + F PDG + G DS Sbjct: 216 DLEKFHVVSCIEEEATPVRCILFNPDGCCLYGGFQDS 252
>YY46_ANASP (Q8YRI1) Hypothetical WD-repeat protein alr3466| Length = 1526 Score = 115 bits (287), Expect = 1e-25 Identities = 58/167 (34%), Positives = 92/167 (55%) Frame = +3 Query: 99 ATKRAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSP 278 ++K Y LQ H S V F S TL +G DQ V LW + + + G TS Sbjct: 1189 SSKCLYILQ---GHTSWVNSVVFNPDGS-TLASGSSDQTVRLWEINSSKCLCTFQGHTSW 1244 Query: 279 VESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSS 458 V S+ F+ M+ +G++ T+++WDI +K + TF GH + S+ +P G ASGS Sbjct: 1245 VNSVVFNPDGSMLASGSSDKTVRLWDISSSKCLHTFQGHTNWVNSVAFNPDGSMLASGSG 1304 Query: 459 DTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 D +++W++ +C+HT+QGHT + + F+PDG + SG D +V+ Sbjct: 1305 DQTVRLWEISSSKCLHTFQGHTSWVSSVTFSPDGTMLASGSDDQTVR 1351 Score = 112 bits (281), Expect = 6e-25 Identities = 58/165 (35%), Positives = 89/165 (53%) Frame = +3 Query: 105 KRAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVE 284 K Y LQ H + V F TL +G DQ V LW + + L G TS V Sbjct: 1149 KCLYTLQ---GHTNWVNAVAFSP-DGATLASGSGDQTVRLWDISSSKCLYILQGHTSWVN 1204 Query: 285 SLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDT 464 S+ F+ + +G++ T+++W+I +K + TF GH S S+ +P G ASGSSD Sbjct: 1205 SVVFNPDGSTLASGSSDQTVRLWEINSSKCLCTFQGHTSWVNSVVFNPDGSMLASGSSDK 1264 Query: 465 NMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 +++WD+ +C+HT+QGHT ++ + F PDG + SG D +V+ Sbjct: 1265 TVRLWDISSSKCLHTFQGHTNWVNSVAFNPDGSMLASGSGDQTVR 1309 Score = 102 bits (255), Expect = 6e-22 Identities = 46/138 (33%), Positives = 78/138 (56%) Frame = +3 Query: 186 TLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEE 365 TL G DQ V LW + + +L G T+ V +++F + +G+ T+++WDI Sbjct: 1130 TLANGSSDQIVRLWDISSKKCLYTLQGHTNWVNAVAFSPDGATLASGSGDQTVRLWDISS 1189 Query: 366 AKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLR 545 +K + GH S S+ +P G ASGSSD +++W++ +C+ T+QGHT ++ + Sbjct: 1190 SKCLYILQGHTSWVNSVVFNPDGSTLASGSSDQTVRLWEINSSKCLCTFQGHTSWVNSVV 1249 Query: 546 FTPDGRWIVSGGADSSVK 599 F PDG + SG +D +V+ Sbjct: 1250 FNPDGSMLASGSSDKTVR 1267 Score = 102 bits (253), Expect = 1e-21 Identities = 50/157 (31%), Positives = 83/157 (52%) Frame = +3 Query: 129 FVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSE 308 F H S V F S L +G D+ V LW + + + G T+ V S++F+ Sbjct: 1238 FQGHTSWVNSVVFNPDGSM-LASGSSDKTVRLWDISSSKCLHTFQGHTNWVNSVAFNPDG 1296 Query: 309 VMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMR 488 M+ +G+ T+++W+I +K + TF GH S +S+ P G ASGS D +++W + Sbjct: 1297 SMLASGSGDQTVRLWEISSSKCLHTFQGHTSWVSSVTFSPDGTMLASGSDDQTVRLWSIS 1356 Query: 489 KKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 C++T+ GHT + + F+PDG + SG D +V+ Sbjct: 1357 SGECLYTFLGHTNWVGSVIFSPDGAILASGSGDQTVR 1393 Score = 102 bits (253), Expect = 1e-21 Identities = 52/157 (33%), Positives = 80/157 (50%) Frame = +3 Query: 129 FVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSE 308 F H S V F L +G +DQ V LW + + +L G TS V S+ F Sbjct: 1028 FQGHTSCVRSVVFSS-DGAMLASGSDDQTVRLWDISSGNCLYTLQGHTSCVRSVVFSPDG 1086 Query: 309 VMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMR 488 M+ +G +++WDI + T G+ S L P G A+GSSD +++WD+ Sbjct: 1087 AMLASGGDDQIVRLWDISSGNCLYTLQGYTSWVRFLVFSPNGVTLANGSSDQIVRLWDIS 1146 Query: 489 KKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 K+C++T QGHT ++ + F+PDG + SG D +V+ Sbjct: 1147 SKKCLYTLQGHTNWVNAVAFSPDGATLASGSGDQTVR 1183 Score = 99.4 bits (246), Expect = 7e-21 Identities = 46/137 (33%), Positives = 76/137 (55%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L +GG+DQ V LW + + +L G TS V L F + V + G++ +++WDI Sbjct: 1089 LASGGDDQIVRLWDISSGNCLYTLQGYTSWVRFLVFSPNGVTLANGSSDQIVRLWDISSK 1148 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 K + T GH + ++ P G ASGS D +++WD+ +C++ QGHT ++ + F Sbjct: 1149 KCLYTLQGHTNWVNAVAFSPDGATLASGSGDQTVRLWDISSSKCLYILQGHTSWVNSVVF 1208 Query: 549 TPDGRWIVSGGADSSVK 599 PDG + SG +D +V+ Sbjct: 1209 NPDGSTLASGSSDQTVR 1225 Score = 99.4 bits (246), Expect = 7e-21 Identities = 53/160 (33%), Positives = 79/160 (49%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 L+ F H S V F S L +G DQ V LW + + G T V S++F+ Sbjct: 941 LKTFKGHTSRVRSVVFSPN-SLMLASGSSDQTVRLWDISSGECLYIFQGHTGWVYSVAFN 999 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 M+ G+ T+++WDI ++ F GH S S+ G ASGS D +++W Sbjct: 1000 LDGSMLATGSGDQTVRLWDISSSQCFYIFQGHTSCVRSVVFSSDGAMLASGSDDQTVRLW 1059 Query: 480 DMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 D+ C++T QGHT + + F+PDG + SGG D V+ Sbjct: 1060 DISSGNCLYTLQGHTSCVRSVVFSPDGAMLASGGDDQIVR 1099 Score = 98.2 bits (243), Expect = 2e-20 Identities = 50/160 (31%), Positives = 80/160 (50%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 L F H + V F S L +G DQ V LW + + + G TS V S++F Sbjct: 1277 LHTFQGHTNWVNSVAFNPDGSM-LASGSGDQTVRLWEISSSKCLHTFQGHTSWVSSVTFS 1335 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 M+ +G+ T+++W I + + TF GH + S+ P G ASGS D +++W Sbjct: 1336 PDGTMLASGSDDQTVRLWSISSGECLYTFLGHTNWVGSVIFSPDGAILASGSGDQTVRLW 1395 Query: 480 DMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 + +C++T QGH + + F+PDG + SG D +V+ Sbjct: 1396 SISSGKCLYTLQGHNNWVGSIVFSPDGTLLASGSDDQTVR 1435 Score = 95.5 bits (236), Expect = 1e-19 Identities = 46/154 (29%), Positives = 81/154 (52%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMI 317 H S V F + + L +G +DQ V LW + + + G TS V S+ F + +M+ Sbjct: 905 HNSWVNSVGFSQ-DGKMLASGSDDQTVRLWDISSGQCLKTFKGHTSRVRSVVFSPNSLML 963 Query: 318 GAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKR 497 +G++ T+++WDI + + F GH S+ + G A+GS D +++WD+ + Sbjct: 964 ASGSSDQTVRLWDISSGECLYIFQGHTGWVYSVAFNLDGSMLATGSGDQTVRLWDISSSQ 1023 Query: 498 CIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 C + +QGHT + + F+ DG + SG D +V+ Sbjct: 1024 CFYIFQGHTSCVRSVVFSSDGAMLASGSDDQTVR 1057 Score = 93.2 bits (230), Expect = 5e-19 Identities = 46/137 (33%), Positives = 70/137 (51%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L TG DQ V LW + G TS V S+ F S M+ +G+ T+++WDI Sbjct: 1005 LATGSGDQTVRLWDISSSQCFYIFQGHTSCVRSVVFSSDGAMLASGSDDQTVRLWDISSG 1064 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 + T GH S S+ P G ASG D +++WD+ C++T QG+T + L F Sbjct: 1065 NCLYTLQGHTSCVRSVVFSPDGAMLASGGDDQIVRLWDISSGNCLYTLQGYTSWVRFLVF 1124 Query: 549 TPDGRWIVSGGADSSVK 599 +P+G + +G +D V+ Sbjct: 1125 SPNGVTLANGSSDQIVR 1141 Score = 92.4 bits (228), Expect = 9e-19 Identities = 46/160 (28%), Positives = 78/160 (48%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 L F H S V+ F L +G +DQ V LW++ + + G T+ V S+ F Sbjct: 1319 LHTFQGHTSWVSSVTFSP-DGTMLASGSDDQTVRLWSISSGECLYTFLGHTNWVGSVIFS 1377 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 ++ +G+ T+++W I K + T GH + S+ P G ASGS D +++W Sbjct: 1378 PDGAILASGSGDQTVRLWSISSGKCLYTLQGHNNWVGSIVFSPDGTLLASGSDDQTVRLW 1437 Query: 480 DMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 ++ C++T GH + + F+ DG + SG D ++K Sbjct: 1438 NISSGECLYTLHGHINSVRSVAFSSDGLILASGSDDETIK 1477 Score = 91.3 bits (225), Expect = 2e-18 Identities = 43/135 (31%), Positives = 69/135 (51%) Frame = +3 Query: 195 TGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKV 374 TG V W +L+ G S V S+ F M+ +G+ T+++WDI + Sbjct: 881 TGDSGGIVRFWEAATGKELLTCKGHNSWVNSVGFSQDGKMLASGSDDQTVRLWDISSGQC 940 Query: 375 VRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTP 554 ++TF GH S S+ P ASGSSD +++WD+ C++ +QGHTG + + F Sbjct: 941 LKTFKGHTSRVRSVVFSPNSLMLASGSSDQTVRLWDISSGECLYIFQGHTGWVYSVAFNL 1000 Query: 555 DGRWIVSGGADSSVK 599 DG + +G D +V+ Sbjct: 1001 DGSMLATGSGDQTVR 1015 Score = 77.8 bits (190), Expect = 2e-14 Identities = 42/147 (28%), Positives = 73/147 (49%), Gaps = 3/147 (2%) Frame = +3 Query: 168 GKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTS---PVESLSFDSSEVMIGAGAASG 338 G+ S T+I G + +L V A L+ S T V +++F + G + G Sbjct: 827 GRDLSHTVIIGADFTNTSLRCVNFTEANLAYSVFTKILGSVLTVAFSPDGKLFATGDSGG 886 Query: 339 TIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQG 518 ++ W+ K + T GH S S+ G ASGS D +++WD+ +C+ T++G Sbjct: 887 IVRFWEAATGKELLTCKGHNSWVNSVGFSQDGKMLASGSDDQTVRLWDISSGQCLKTFKG 946 Query: 519 HTGRIDVLRFTPDGRWIVSGGADSSVK 599 HT R+ + F+P+ + SG +D +V+ Sbjct: 947 HTSRVRSVVFSPNSLMLASGSSDQTVR 973 Score = 68.6 bits (166), Expect = 1e-11 Identities = 37/130 (28%), Positives = 63/130 (48%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 L F+ H + V F L +G DQ V LW++ + +L G + V S+ F Sbjct: 1361 LYTFLGHTNWVGSVIFSP-DGAILASGSGDQTVRLWSISSGKCLYTLQGHNNWVGSIVFS 1419 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 ++ +G+ T+++W+I + + T GH ++ S+ G ASGS D +K+W Sbjct: 1420 PDGTLLASGSDDQTVRLWNISSGECLYTLHGHINSVRSVAFSSDGLILASGSDDETIKLW 1479 Query: 480 DMRKKRCIHT 509 D++ CI T Sbjct: 1480 DVKTGECIKT 1489 Score = 50.1 bits (118), Expect = 5e-06 Identities = 20/70 (28%), Positives = 40/70 (57%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L +G +DQ V LW + + +L G + V S++F S +++ +G+ TIK+WD++ Sbjct: 1425 LASGSDDQTVRLWNISSGECLYTLHGHINSVRSVAFSSDGLILASGSDDETIKLWDVKTG 1484 Query: 369 KVVRTFTGHR 398 + ++T + Sbjct: 1485 ECIKTLKSEK 1494
>HETE1_PODAN (Q00808) Vegetatible incompatibility protein HET-E-1| Length = 1356 Score = 96.3 bits (238), Expect = 6e-20 Identities = 50/159 (31%), Positives = 75/159 (47%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 Q H V F R + +G +D+ + +W T +L G V+S++F Sbjct: 877 QTLEGHGGSVWSVAFSPDRER-VASGSDDKTIKIWDAASGTCTQTLEGHGGRVQSVAFSP 935 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 + +G+ TIKIWD +T GH S+ S+ P G ASGS D +KIWD Sbjct: 936 DGQRVASGSDDHTIKIWDAASGTCTQTLEGHGSSVLSVAFSPDGQRVASGSGDKTIKIWD 995 Query: 483 MRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 C T +GH G + + F+PDG+ + SG D ++K Sbjct: 996 TASGTCTQTLEGHGGSVWSVAFSPDGQRVASGSDDKTIK 1034 Score = 95.1 bits (235), Expect = 1e-19 Identities = 51/159 (32%), Positives = 74/159 (46%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 Q H V F R + +G D + +W T +L G V S++F Sbjct: 1087 QTLEGHGDSVWSVAFSPDGQR-VASGSIDGTIKIWDAASGTCTQTLEGHGGWVHSVAFSP 1145 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 + +G+ GTIKIWD +T GH S+ P G ASGSSD +KIWD Sbjct: 1146 DGQRVASGSIDGTIKIWDAASGTCTQTLEGHGGWVQSVAFSPDGQRVASGSSDKTIKIWD 1205 Query: 483 MRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 C T +GH G + + F+PDG+ + SG +D+++K Sbjct: 1206 TASGTCTQTLEGHGGWVQSVAFSPDGQRVASGSSDNTIK 1244 Score = 93.2 bits (230), Expect = 5e-19 Identities = 50/159 (31%), Positives = 73/159 (45%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 Q H V F R + +G +D + +W T +L G S V S++F Sbjct: 919 QTLEGHGGRVQSVAFSPDGQR-VASGSDDHTIKIWDAASGTCTQTLEGHGSSVLSVAFSP 977 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 + +G+ TIKIWD +T GH + S+ P G ASGS D +KIWD Sbjct: 978 DGQRVASGSGDKTIKIWDTASGTCTQTLEGHGGSVWSVAFSPDGQRVASGSDDKTIKIWD 1037 Query: 483 MRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 C T +GH G + + F+PDG+ + SG D ++K Sbjct: 1038 TASGTCTQTLEGHGGWVQSVVFSPDGQRVASGSDDHTIK 1076 Score = 93.2 bits (230), Expect = 5e-19 Identities = 49/159 (30%), Positives = 72/159 (45%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 Q H S V F R + +G +D+ + +W T +L G V S++F Sbjct: 835 QTLEGHGSSVLSVAFSADGQR-VASGSDDKTIKIWDTASGTGTQTLEGHGGSVWSVAFSP 893 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 + +G+ TIKIWD +T GH S+ P G ASGS D +KIWD Sbjct: 894 DRERVASGSDDKTIKIWDAASGTCTQTLEGHGGRVQSVAFSPDGQRVASGSDDHTIKIWD 953 Query: 483 MRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 C T +GH + + F+PDG+ + SG D ++K Sbjct: 954 AASGTCTQTLEGHGSSVLSVAFSPDGQRVASGSGDKTIK 992 Score = 91.7 bits (226), Expect = 1e-18 Identities = 45/135 (33%), Positives = 67/135 (49%) Frame = +3 Query: 195 TGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKV 374 +G +D + +W T +L G V S++F + +G+ GTIKIWD Sbjct: 1068 SGSDDHTIKIWDAVSGTCTQTLEGHGDSVWSVAFSPDGQRVASGSIDGTIKIWDAASGTC 1127 Query: 375 VRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTP 554 +T GH S+ P G ASGS D +KIWD C T +GH G + + F+P Sbjct: 1128 TQTLEGHGGWVHSVAFSPDGQRVASGSIDGTIKIWDAASGTCTQTLEGHGGWVQSVAFSP 1187 Query: 555 DGRWIVSGGADSSVK 599 DG+ + SG +D ++K Sbjct: 1188 DGQRVASGSSDKTIK 1202 Score = 90.9 bits (224), Expect = 3e-18 Identities = 49/159 (30%), Positives = 73/159 (45%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 Q H V F R + +G +D+ + +W T +L G V+S+ F Sbjct: 1003 QTLEGHGGSVWSVAFSPDGQR-VASGSDDKTIKIWDTASGTCTQTLEGHGGWVQSVVFSP 1061 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 + +G+ TIKIWD +T GH + S+ P G ASGS D +KIWD Sbjct: 1062 DGQRVASGSDDHTIKIWDAVSGTCTQTLEGHGDSVWSVAFSPDGQRVASGSIDGTIKIWD 1121 Query: 483 MRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 C T +GH G + + F+PDG+ + SG D ++K Sbjct: 1122 AASGTCTQTLEGHGGWVHSVAFSPDGQRVASGSIDGTIK 1160 Score = 87.4 bits (215), Expect = 3e-17 Identities = 49/159 (30%), Positives = 71/159 (44%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 Q H S V F R + +G D+ + +W T +L G V S++F Sbjct: 961 QTLEGHGSSVLSVAFSPDGQR-VASGSGDKTIKIWDTASGTCTQTLEGHGGSVWSVAFSP 1019 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 + +G+ TIKIWD +T GH S+ P G ASGS D +KIWD Sbjct: 1020 DGQRVASGSDDKTIKIWDTASGTCTQTLEGHGGWVQSVVFSPDGQRVASGSDDHTIKIWD 1079 Query: 483 MRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 C T +GH + + F+PDG+ + SG D ++K Sbjct: 1080 AVSGTCTQTLEGHGDSVWSVAFSPDGQRVASGSIDGTIK 1118 Score = 65.1 bits (157), Expect = 1e-10 Identities = 34/105 (32%), Positives = 48/105 (45%) Frame = +3 Query: 195 TGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKV 374 +G D + +W T +L G V+S++F + +G++ TIKIWD Sbjct: 1152 SGSIDGTIKIWDAASGTCTQTLEGHGGWVQSVAFSPDGQRVASGSSDKTIKIWDTASGTC 1211 Query: 375 VRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHT 509 +T GH S+ P G ASGSSD +KIWD C T Sbjct: 1212 TQTLEGHGGWVQSVAFSPDGQRVASGSSDNTIKIWDTASGTCTQT 1256 Score = 53.9 bits (128), Expect = 3e-07 Identities = 29/87 (33%), Positives = 42/87 (48%) Frame = +3 Query: 339 TIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQG 518 TI + + E +T GH S+ S+ G ASGS D +KIWD T +G Sbjct: 822 TISVVEAEWNACTQTLEGHGSSVLSVAFSADGQRVASGSDDKTIKIWDTASGTGTQTLEG 881 Query: 519 HTGRIDVLRFTPDGRWIVSGGADSSVK 599 H G + + F+PD + SG D ++K Sbjct: 882 HGGSVWSVAFSPDRERVASGSDDKTIK 908
>Y2800_ANASP (Q8YTC2) Hypothetical WD-repeat protein alr2800| Length = 1258 Score = 94.0 bits (232), Expect = 3e-19 Identities = 48/160 (30%), Positives = 76/160 (47%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 LQ H V C F TL + D + LW V + + +L T V S++F Sbjct: 761 LQTLTGHTDWVRCVAFSP-DGNTLASSAADHTIKLWDVSQGKCLRTLKSHTGWVRSVAFS 819 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 + + +G+ TIKIW+ + ++T+ GH ++ S+ P SGS D +K+W Sbjct: 820 ADGQTLASGSGDRTIKIWNYHTGECLKTYIGHTNSVYSIAYSPDSKILVSGSGDRTIKLW 879 Query: 480 DMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 D + CI T GHT + + F+PDG+ + D SV+ Sbjct: 880 DCQTHICIKTLHGHTNEVCSVAFSPDGQTLACVSLDQSVR 919 Score = 93.2 bits (230), Expect = 5e-19 Identities = 45/138 (32%), Positives = 72/138 (52%) Frame = +3 Query: 186 TLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEE 365 TL + D+ + LW + T + +L+G T V ++F + + AA TIK+WD+ + Sbjct: 740 TLASASGDKTIKLWDIQDGTCLQTLTGHTDWVRCVAFSPDGNTLASSAADHTIKLWDVSQ 799 Query: 366 AKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLR 545 K +RT H S+ G ASGS D +KIW+ C+ TY GHT + + Sbjct: 800 GKCLRTLKSHTGWVRSVAFSADGQTLASGSGDRTIKIWNYHTGECLKTYIGHTNSVYSIA 859 Query: 546 FTPDGRWIVSGGADSSVK 599 ++PD + +VSG D ++K Sbjct: 860 YSPDSKILVSGSGDRTIK 877 Score = 90.9 bits (224), Expect = 3e-18 Identities = 42/137 (30%), Positives = 76/137 (55%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L + G D+ V LW+V + +L+G V S++F + + + TIK+WDI++ Sbjct: 699 LASCGADENVKLWSVRDGVCIKTLTGHEHEVFSVAFHPDGETLASASGDKTIKLWDIQDG 758 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 ++T TGH + P G+ AS ++D +K+WD+ + +C+ T + HTG + + F Sbjct: 759 TCLQTLTGHTDWVRCVAFSPDGNTLASSAADHTIKLWDVSQGKCLRTLKSHTGWVRSVAF 818 Query: 549 TPDGRWIVSGGADSSVK 599 + DG+ + SG D ++K Sbjct: 819 SADGQTLASGSGDRTIK 835 Score = 85.5 bits (210), Expect = 1e-16 Identities = 45/137 (32%), Positives = 68/137 (49%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L + DQ V LW V L G ++ V S F + +I + T+KIWD ++ Sbjct: 1077 LASASADQSVRLWDCCTGRCVGILRGHSNRVYSAIFSPNGEIIATCSTDQTVKIWDWQQG 1136 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 K ++T TGH + + P G AS S D ++IWD+ +C H GHT + + F Sbjct: 1137 KCLKTLTGHTNWVFDIAFSPDGKILASASHDQTVRIWDVNTGKCHHICIGHTHLVSSVAF 1196 Query: 549 TPDGRWIVSGGADSSVK 599 +PDG + SG D +V+ Sbjct: 1197 SPDGEVVASGSQDQTVR 1213 Score = 85.1 bits (209), Expect = 1e-16 Identities = 41/137 (29%), Positives = 68/137 (49%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L T D V +W V +L G ++ V + F ++ + A +K+W + + Sbjct: 657 LATCDTDCHVRVWEVKSGKLLLICRGHSNWVRFVVFSPDGEILASCGADENVKLWSVRDG 716 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 ++T TGH S+ HP G+ AS S D +K+WD++ C+ T GHT + + F Sbjct: 717 VCIKTLTGHEHEVFSVAFHPDGETLASASGDKTIKLWDIQDGTCLQTLTGHTDWVRCVAF 776 Query: 549 TPDGRWIVSGGADSSVK 599 +PDG + S AD ++K Sbjct: 777 SPDGNTLASSAADHTIK 793 Score = 77.4 bits (189), Expect = 3e-14 Identities = 36/139 (25%), Positives = 71/139 (51%) Frame = +3 Query: 183 RTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIE 362 + + TG D V LW + + +LS + + +++ ++ + +A ++++WD Sbjct: 1033 KIIATGSADCTVKLWNISTGQCLKTLSEHSDKILGMAWSPDGQLLASASADQSVRLWDCC 1092 Query: 363 EAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVL 542 + V GH + S P G+ A+ S+D +KIWD ++ +C+ T GHT + + Sbjct: 1093 TGRCVGILRGHSNRVYSAIFSPNGEIIATCSTDQTVKIWDWQQGKCLKTLTGHTNWVFDI 1152 Query: 543 RFTPDGRWIVSGGADSSVK 599 F+PDG+ + S D +V+ Sbjct: 1153 AFSPDGKILASASHDQTVR 1171 Score = 77.4 bits (189), Expect = 3e-14 Identities = 40/140 (28%), Positives = 68/140 (48%) Frame = +3 Query: 180 SRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDI 359 S+TL + D V LW + L T V ++ F +I G+A T+K+W+I Sbjct: 990 SQTLASASTDSSVRLWNISTGQCFQILLEHTDWVYAVVFHPQGKIIATGSADCTVKLWNI 1049 Query: 360 EEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDV 539 + ++T + H + P G AS S+D ++++WD RC+ +GH+ R+ Sbjct: 1050 STGQCLKTLSEHSDKILGMAWSPDGQLLASASADQSVRLWDCCTGRCVGILRGHSNRVYS 1109 Query: 540 LRFTPDGRWIVSGGADSSVK 599 F+P+G I + D +VK Sbjct: 1110 AIFSPNGEIIATCSTDQTVK 1129 Score = 75.5 bits (184), Expect = 1e-13 Identities = 37/139 (26%), Positives = 72/139 (51%) Frame = +3 Query: 183 RTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIE 362 +TL +G D+ + +W + + G T+ V S+++ ++ +G+ TIK+WD + Sbjct: 823 QTLASGSGDRTIKIWNYHTGECLKTYIGHTNSVYSIAYSPDSKILVSGSGDRTIKLWDCQ 882 Query: 363 EAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVL 542 ++T GH + S+ P G A S D ++++W+ R +C+ + G+T + Sbjct: 883 THICIKTLHGHTNEVCSVAFSPDGQTLACVSLDQSVRLWNCRTGQCLKAWYGNTDWALPV 942 Query: 543 RFTPDGRWIVSGGADSSVK 599 F+PD + + SG D +VK Sbjct: 943 AFSPDRQILASGSNDKTVK 961 Score = 75.1 bits (183), Expect = 1e-13 Identities = 35/137 (25%), Positives = 69/137 (50%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L +G D+ V LW + SL G T + ++F + + + ++++W+I Sbjct: 951 LASGSNDKTVKLWDWQTGKYISSLEGHTDFIYGIAFSPDSQTLASASTDSSVRLWNISTG 1010 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 + + H ++ HP G A+GS+D +K+W++ +C+ T H+ +I + + Sbjct: 1011 QCFQILLEHTDWVYAVVFHPQGKIIATGSADCTVKLWNISTGQCLKTLSEHSDKILGMAW 1070 Query: 549 TPDGRWIVSGGADSSVK 599 +PDG+ + S AD SV+ Sbjct: 1071 SPDGQLLASASADQSVR 1087 Score = 75.1 bits (183), Expect = 1e-13 Identities = 39/160 (24%), Positives = 79/160 (49%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 L+ ++ H + V + S+ L++G D+ + LW + +L G T+ V S++F Sbjct: 845 LKTYIGHTNSVYSIAYSP-DSKILVSGSGDRTIKLWDCQTHICIKTLHGHTNEVCSVAFS 903 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 + + ++++W+ + ++ + G+ + P ASGS+D +K+W Sbjct: 904 PDGQTLACVSLDQSVRLWNCRTGQCLKAWYGNTDWALPVAFSPDRQILASGSNDKTVKLW 963 Query: 480 DMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 D + + I + +GHT I + F+PD + + S DSSV+ Sbjct: 964 DWQTGKYISSLEGHTDFIYGIAFSPDSQTLASASTDSSVR 1003 Score = 69.7 bits (169), Expect = 6e-12 Identities = 39/154 (25%), Positives = 70/154 (45%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMI 317 H ++V F +TL DQ V LW + + G T ++F ++ Sbjct: 893 HTNEVCSVAFSP-DGQTLACVSLDQSVRLWNCRTGQCLKAWYGNTDWALPVAFSPDRQIL 951 Query: 318 GAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKR 497 +G+ T+K+WD + K + + GH + P AS S+D+++++W++ + Sbjct: 952 ASGSNDKTVKLWDWQTGKYISSLEGHTDFIYGIAFSPDSQTLASASTDSSVRLWNISTGQ 1011 Query: 498 CIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 C HT + + F P G+ I +G AD +VK Sbjct: 1012 CFQILLEHTDWVYAVVFHPQGKIIATGSADCTVK 1045 Score = 58.5 bits (140), Expect = 1e-08 Identities = 32/122 (26%), Positives = 59/122 (48%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMI 317 H++ V A F + T DQ V +W + + +L+G T+ V ++F ++ Sbjct: 1103 HSNRVYSAIFSPN-GEIIATCSTDQTVKIWDWQQGKCLKTLTGHTNWVFDIAFSPDGKIL 1161 Query: 318 GAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKR 497 + + T++IWD+ K GH +S+ P G+ ASGS D ++IW+++ Sbjct: 1162 ASASHDQTVRIWDVNTGKCHHICIGHTHLVSSVAFSPDGEVVASGSQDQTVRIWNVKTGE 1221 Query: 498 CI 503 C+ Sbjct: 1222 CL 1223 Score = 45.4 bits (106), Expect = 1e-04 Identities = 21/72 (29%), Positives = 39/72 (54%) Frame = +3 Query: 384 FTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGR 563 FT N S P G A+ +D ++++W+++ + + +GH+ + + F+PDG Sbjct: 638 FTETLGNILSAAFSPEGQLLATCDTDCHVRVWEVKSGKLLLICRGHSNWVRFVVFSPDGE 697 Query: 564 WIVSGGADSSVK 599 + S GAD +VK Sbjct: 698 ILASCGADENVK 709
>WD51B_HUMAN (Q8TC44) WD-repeat protein 51B| Length = 478 Score = 91.3 bits (225), Expect = 2e-18 Identities = 47/159 (29%), Positives = 77/159 (48%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 L H V CAKF R +++ ED+ + +W V + S + F+ Sbjct: 137 LYSLYRHTHWVRCAKFSP-DGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFN 195 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 S I + + T+K+WD+ K+++ + H + HP G++ + SSD +KI Sbjct: 196 PSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKIL 255 Query: 480 DMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 D+ + R I+T QGHTG + + F+ G SGGAD+ V Sbjct: 256 DLLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQV 294 Score = 85.5 bits (210), Expect = 1e-16 Identities = 46/161 (28%), Positives = 78/161 (48%) Frame = +3 Query: 117 KLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSF 296 K EF AH + V F + L T ED+ + +W++ + + SL T V F Sbjct: 94 KFSEFKAHTAPVRSVDFSA-DGQFLATASEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKF 152 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 +I + + TIKIWD + V F+ +D +P G AS SD +K+ Sbjct: 153 SPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKV 212 Query: 477 WDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 WD+R + + YQ H+G ++ + F P G ++++ +D ++K Sbjct: 213 WDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLK 253 Score = 75.5 bits (184), Expect = 1e-13 Identities = 44/164 (26%), Positives = 69/164 (42%) Frame = +3 Query: 108 RAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVES 287 RAY+ +V H VT +F L + D+ V LW K T+PV S Sbjct: 52 RAYR---YVGHKDVVTSVQFSPH-GNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRS 107 Query: 288 LSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTN 467 + F + + + +IK+W + + + + H P G S S D Sbjct: 108 VDFSADGQFLATASEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKT 167 Query: 468 MKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 +KIWD K+C++ + G + + F P G I S G+D +VK Sbjct: 168 IKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVK 211 Score = 67.4 bits (163), Expect = 3e-11 Identities = 39/157 (24%), Positives = 69/157 (43%) Frame = +3 Query: 129 FVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSE 308 F H + +T + L T D + LW G V S+ F Sbjct: 14 FKGHKAAITSLDLSPN-GKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHG 72 Query: 309 VMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMR 488 ++ + + T+++W ++ F H + S+D G F A+ S D ++K+W M Sbjct: 73 NLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMY 132 Query: 489 KKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 ++R +++ HT + +F+PDGR IVS D ++K Sbjct: 133 RQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIK 169 Score = 51.6 bits (122), Expect = 2e-06 Identities = 27/97 (27%), Positives = 47/97 (48%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 + + G DQ V +W V + + V +SF S + ++ GT+KI D+ E Sbjct: 201 IASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEG 260 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 +++ T GH ++ G+ FASG +DT + +W Sbjct: 261 RLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLW 297 Score = 50.4 bits (119), Expect = 4e-06 Identities = 25/124 (20%), Positives = 52/124 (41%) Frame = +3 Query: 228 AVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNC 407 A P G + + SL + + + + +W+ + + GH+ Sbjct: 4 ATEDPVLERYFKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVV 63 Query: 408 ASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGAD 587 S+ P G+ AS S D +++W K+ ++ HT + + F+ DG+++ + D Sbjct: 64 TSVQFSPHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASED 123 Query: 588 SSVK 599 S+K Sbjct: 124 KSIK 127
>WD51B_MOUSE (Q8BHD1) WD-repeat protein 51B| Length = 476 Score = 90.1 bits (222), Expect = 4e-18 Identities = 48/159 (30%), Positives = 77/159 (48%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 L H V CAKF R +++ ED+ + +W V + S + F+ Sbjct: 137 LYSLYRHTHWVRCAKFSP-DGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFN 195 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 + I + + +KIWDI K+++ + H L HP G+ + SSD +K+ Sbjct: 196 PNGTCIASAGSDHAVKIWDIRMNKLLQHYQVHSCGVNCLSFHPLGNSLVTASSDGTVKML 255 Query: 480 DMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 D+ + R I+T QGHTG + + F+ DG + SGGAD+ V Sbjct: 256 DLIEGRLIYTLQGHTGPVFTVSFSKDGELLTSGGADAQV 294 Score = 81.6 bits (200), Expect = 2e-15 Identities = 50/164 (30%), Positives = 78/164 (47%) Frame = +3 Query: 108 RAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVES 287 R K EF AH + V F + L+T ED+ + +W++ + + SL T V Sbjct: 91 RKGKSSEFKAHTAPVRSVDFSA-DGQLLVTASEDKSIKVWSMFRQRFLYSLYRHTHWVRC 149 Query: 288 LSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTN 467 F +I + + TIKIWD + V F+ +D +P G AS SD Sbjct: 150 AKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPNGTCIASAGSDHA 209 Query: 468 MKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 +KIWD+R + + YQ H+ ++ L F P G +V+ +D +VK Sbjct: 210 VKIWDIRMNKLLQHYQVHSCGVNCLSFHPLGNSLVTASSDGTVK 253 Score = 75.1 bits (183), Expect = 1e-13 Identities = 43/164 (26%), Positives = 73/164 (44%) Frame = +3 Query: 108 RAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVES 287 RAY+ +V H VT +F + L + D+ V LW + + T+PV S Sbjct: 52 RAYR---YVGHKDVVTSLQFSPQ-GNLLASASRDRTVRLWVLDRKGKSSEFKAHTAPVRS 107 Query: 288 LSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTN 467 + F + ++ + +IK+W + + + + H P G S S D Sbjct: 108 VDFSADGQLLVTASEDKSIKVWSMFRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKT 167 Query: 468 MKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 +KIWD K+C++ + G + + F P+G I S G+D +VK Sbjct: 168 IKIWDTTNKQCVNNFSDSVGFANFVDFNPNGTCIASAGSDHAVK 211 Score = 71.2 bits (173), Expect = 2e-12 Identities = 39/159 (24%), Positives = 72/159 (45%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 + F H + +T A F + + T D + LW++ G V SL F Sbjct: 12 RSFKGHKAAITSADFSPNCKQ-IATASWDTFLMLWSLKPHARAYRYVGHKDVVTSLQFSP 70 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 ++ + + T+++W ++ F H + S+D G + S D ++K+W Sbjct: 71 QGNLLASASRDRTVRLWVLDRKGKSSEFKAHTAPVRSVDFSADGQLLVTASEDKSIKVWS 130 Query: 483 MRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 M ++R +++ HT + +F+PDGR IVS D ++K Sbjct: 131 MFRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIK 169 Score = 54.3 bits (129), Expect = 3e-07 Identities = 28/120 (23%), Positives = 53/120 (44%) Frame = +3 Query: 240 PTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLD 419 P S G + + S F + I + + +W ++ + GH+ SL Sbjct: 8 PILERSFKGHKAAITSADFSPNCKQIATASWDTFLMLWSLKPHARAYRYVGHKDVVTSLQ 67 Query: 420 SHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 P G+ AS S D +++W + +K ++ HT + + F+ DG+ +V+ D S+K Sbjct: 68 FSPQGNLLASASRDRTVRLWVLDRKGKSSEFKAHTAPVRSVDFSADGQLLVTASEDKSIK 127 Score = 47.8 bits (112), Expect = 2e-05 Identities = 23/81 (28%), Positives = 41/81 (50%) Frame = +3 Query: 357 IEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRID 536 +E+ + R+F GH++ S D P A+ S DT + +W ++ + Y GH + Sbjct: 5 LEDPILERSFKGHKAAITSADFSPNCKQIATASWDTFLMLWSLKPHARAYRYVGHKDVVT 64 Query: 537 VLRFTPDGRWIVSGGADSSVK 599 L+F+P G + S D +V+ Sbjct: 65 SLQFSPQGNLLASASRDRTVR 85 Score = 42.7 bits (99), Expect = 8e-04 Identities = 22/97 (22%), Positives = 42/97 (43%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 + + G D V +W + + + V LSF + ++ GT+K+ D+ E Sbjct: 201 IASAGSDHAVKIWDIRMNKLLQHYQVHSCGVNCLSFHPLGNSLVTASSDGTVKMLDLIEG 260 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 +++ T GH ++ G+ SG +D + IW Sbjct: 261 RLIYTLQGHTGPVFTVSFSKDGELLTSGGADAQVLIW 297 Score = 39.3 bits (90), Expect = 0.009 Identities = 21/78 (26%), Positives = 36/78 (46%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 LQ + H+ V C F +L+T D V + + + + +L G T PV ++SF Sbjct: 221 LQHYQVHSCGVNCLSFHP-LGNSLVTASSDGTVKMLDLIEGRLIYTLQGHTGPVFTVSFS 279 Query: 300 SSEVMIGAGAASGTIKIW 353 ++ +G A + IW Sbjct: 280 KDGELLTSGGADAQVLIW 297
>WD51B_PONPY (Q5RD06) WD-repeat protein 51B| Length = 451 Score = 89.0 bits (219), Expect = 1e-17 Identities = 46/159 (28%), Positives = 76/159 (47%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 L H V CAKF R +++ ED+ + +W V + S + F+ Sbjct: 137 LYSLYRHTHWVRCAKFSP-DGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFN 195 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 S I + + T+K+WD+ K+++ + H + HP ++ + SSD +KI Sbjct: 196 PSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSDNYLVTASSDGTLKIL 255 Query: 480 DMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 D+ + R I+T QGHTG + + F+ G SGGAD+ V Sbjct: 256 DLLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQV 294 Score = 83.2 bits (204), Expect = 5e-16 Identities = 46/161 (28%), Positives = 77/161 (47%) Frame = +3 Query: 117 KLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSF 296 K EF AH + V F + L T ED+ + +W++ + + SL T V F Sbjct: 94 KFSEFKAHTAPVRSVDFSA-DGQFLATASEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKF 152 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 +I + + TIKIWD + V F+ +D +P G AS SD +K+ Sbjct: 153 SPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKV 212 Query: 477 WDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 WD+R + + YQ H+G ++ + F P ++V+ +D ++K Sbjct: 213 WDVRVNKLLQHYQVHSGGVNCISFHPSDNYLVTASSDGTLK 253 Score = 75.5 bits (184), Expect = 1e-13 Identities = 44/164 (26%), Positives = 69/164 (42%) Frame = +3 Query: 108 RAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVES 287 RAY+ +V H VT +F L + D+ V LW K T+PV S Sbjct: 52 RAYR---YVGHKDVVTSVQFSPH-GNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRS 107 Query: 288 LSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTN 467 + F + + + +IK+W + + + + H P G S S D Sbjct: 108 VDFSADGQFLATASEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKT 167 Query: 468 MKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 +KIWD K+C++ + G + + F P G I S G+D +VK Sbjct: 168 IKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVK 211 Score = 67.4 bits (163), Expect = 3e-11 Identities = 39/157 (24%), Positives = 69/157 (43%) Frame = +3 Query: 129 FVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSE 308 F H + +T + L T D + LW G V S+ F Sbjct: 14 FKGHKAAITSLDLSPN-GKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHG 72 Query: 309 VMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMR 488 ++ + + T+++W ++ F H + S+D G F A+ S D ++K+W M Sbjct: 73 NLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMY 132 Query: 489 KKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 ++R +++ HT + +F+PDGR IVS D ++K Sbjct: 133 RQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIK 169 Score = 53.5 bits (127), Expect = 4e-07 Identities = 27/97 (27%), Positives = 48/97 (49%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 + + G DQ V +W V + + V +SF S+ + ++ GT+KI D+ E Sbjct: 201 IASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSDNYLVTASSDGTLKILDLLEG 260 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 +++ T GH ++ G+ FASG +DT + +W Sbjct: 261 RLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLW 297 Score = 50.4 bits (119), Expect = 4e-06 Identities = 25/124 (20%), Positives = 52/124 (41%) Frame = +3 Query: 228 AVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNC 407 A P G + + SL + + + + +W+ + + GH+ Sbjct: 4 ATEDPVLERYFKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVV 63 Query: 408 ASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGAD 587 S+ P G+ AS S D +++W K+ ++ HT + + F+ DG+++ + D Sbjct: 64 TSVQFSPHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASED 123 Query: 588 SSVK 599 S+K Sbjct: 124 KSIK 127
>FBXW7_DROME (Q9VZF4) F-box/WD-repeat protein 7 (F-box and WD-40 domain protein 7)| (Protein archipelago) Length = 1326 Score = 89.0 bits (219), Expect = 1e-17 Identities = 50/162 (30%), Positives = 83/162 (51%), Gaps = 2/162 (1%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 L+ V H V ++ + +I+G D+ + +W + V +L G TS V + Sbjct: 1028 LRTLVGHTGGVWSSQM---SGNIIISGSTDRTLKVWDMDSGACVHTLQGHTSTVRCMHLH 1084 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRS--NCASLDSHPFGDFFASGSSDTNMK 473 S+V+ +G+ T+++WDIE+ + GH + C D G SG+ D +K Sbjct: 1085 GSKVV--SGSRDATLRVWDIEQGSCLHVLVGHLAAVRCVQYD----GKLIVSGAYDYMVK 1138 Query: 474 IWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 IW ++ C+HT QGHT R+ L+F DG +VSG D+S++ Sbjct: 1139 IWHPERQECLHTLQGHTNRVYSLQF--DGLHVVSGSLDTSIR 1178 Score = 79.7 bits (195), Expect = 6e-15 Identities = 48/179 (26%), Positives = 91/179 (50%), Gaps = 9/179 (5%) Frame = +3 Query: 90 SRMATKRAYKLQE------FVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAV 251 SR AT R + +++ V H + V C ++ + +++G D V +W + + Sbjct: 1092 SRDATLRVWDIEQGSCLHVLVGHLAAVRCVQYD---GKLIVSGAYDYMVKIWHPERQECL 1148 Query: 252 LSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPF 431 +L G T+ V SL FD V+ +G+ +I++WD+E T GH+S + ++ Sbjct: 1149 HTLQGHTNRVYSLQFDGLHVV--SGSLDTSIRVWDVETGNCKHTLMGHQSLTSGMELRQ- 1205 Query: 432 GDFFASGSSDTNMKIWDMRKKRCIHTYQG---HTGRIDVLRFTPDGRWIVSGGADSSVK 599 + SG++D+ +K+WD+ +C+ T G H + L+F + R++V+ D +VK Sbjct: 1206 -NILVSGNADSTVKVWDITTGQCLQTLSGPNKHHSAVTCLQF--NSRFVVTSSDDGTVK 1261 Score = 67.8 bits (164), Expect = 2e-11 Identities = 44/154 (28%), Positives = 71/154 (46%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMI 317 H S V C +++G D + +W + + + + L G + V + +D +I Sbjct: 1074 HTSTVRCMHLH---GSKVVSGSRDATLRVWDIEQGSCLHVLVGHLAAVRCVQYDGK--LI 1128 Query: 318 GAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKR 497 +GA +KIW E + + T GH + SL G SGS DT++++WD+ Sbjct: 1129 VSGAYDYMVKIWHPERQECLHTLQGHTNRVYSLQFD--GLHVVSGSLDTSIRVWDVETGN 1186 Query: 498 CIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 C HT GH + + +VSG ADS+VK Sbjct: 1187 CKHTLMGHQSLTSGMELRQN--ILVSGNADSTVK 1218 Score = 67.8 bits (164), Expect = 2e-11 Identities = 34/107 (31%), Positives = 55/107 (51%) Frame = +3 Query: 279 VESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSS 458 + L F + ++ +G+ T+K+W K +RT GH S S G+ SGS+ Sbjct: 998 ITCLQFSGNRIV--SGSDDNTLKVWSAVNGKCLRTLVGHTGGVWS--SQMSGNIIISGST 1053 Query: 459 DTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 D +K+WDM C+HT QGHT + + G +VSG D++++ Sbjct: 1054 DRTLKVWDMDSGACVHTLQGHTSTVRCMHL--HGSKVVSGSRDATLR 1098 Score = 36.2 bits (82), Expect = 0.074 Identities = 24/81 (29%), Positives = 39/81 (48%), Gaps = 3/81 (3%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLT---SPVESLSFDSSEVMIGAGAASGTIKIWDI 359 L++G D V +W + + +LSG S V L F+S V+ + GT+K+WD+ Sbjct: 1208 LVSGNADSTVKVWDITTGQCLQTLSGPNKHHSAVTCLQFNSRFVVTSSD--DGTVKLWDV 1265 Query: 360 EEAKVVRTFTGHRSNCASLDS 422 + +R N +LDS Sbjct: 1266 KTGDFIR-------NLVALDS 1279
>Y2124_ANASP (Q8YV57) Hypothetical WD-repeat protein all2124| Length = 1683 Score = 88.6 bits (218), Expect = 1e-17 Identities = 47/160 (29%), Positives = 77/160 (48%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 L+ + H ++V F +TL + D V LW V +L G T V +SF Sbjct: 1439 LKTLIGHDNEVNKVNFSP-DGKTLASASRDNTVKLWNVSDGKFKKTLKGHTDEVFWVSFS 1497 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 +I + +A TI++WD ++++ H S++ +P G AS S+D +K+W Sbjct: 1498 PDGKIIASASADKTIRLWDSFSGNLIKSLPAHNDLVYSVNFNPDGSMLASTSADKTVKLW 1557 Query: 480 DMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 +HT+ GH+ + F+PDGR+I S D +VK Sbjct: 1558 RSHDGHLLHTFSGHSNVVYSSSFSPDGRYIASASEDKTVK 1597 Score = 87.8 bits (216), Expect = 2e-17 Identities = 38/139 (27%), Positives = 74/139 (53%) Frame = +3 Query: 183 RTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIE 362 +T+ +GG D+ + LW T + +++G V ++ F + + ++ +IK+WD Sbjct: 1126 QTIASGGSDKTIKLWQTSDGTLLKTITGHEQTVNNVYFSPDGKNLASASSDHSIKLWDTT 1185 Query: 363 EAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVL 542 +++ T TGH + ++ P G A+GS D +K+W + + + T GH ++ L Sbjct: 1186 SGQLLMTLTGHSAGVITVRFSPDGQTIAAGSEDKTVKLWHRQDGKLLKTLNGHQDWVNSL 1245 Query: 543 RFTPDGRWIVSGGADSSVK 599 F+PDG+ + S AD ++K Sbjct: 1246 SFSPDGKTLASASADKTIK 1264 Score = 87.4 bits (215), Expect = 3e-17 Identities = 45/142 (31%), Positives = 75/142 (52%) Frame = +3 Query: 174 RTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIW 353 R +T+ +G D+ + LW+ +L+G V S+SF I +G + TIK+W Sbjct: 1082 RDGQTIASGSLDKTIKLWS-RDGRLFRTLNGHEDAVYSVSFSPDGQTIASGGSDKTIKLW 1140 Query: 354 DIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRI 533 + +++T TGH ++ P G AS SSD ++K+WD + + T GH+ + Sbjct: 1141 QTSDGTLLKTITGHEQTVNNVYFSPDGKNLASASSDHSIKLWDTTSGQLLMTLTGHSAGV 1200 Query: 534 DVLRFTPDGRWIVSGGADSSVK 599 +RF+PDG+ I +G D +VK Sbjct: 1201 ITVRFSPDGQTIAAGSEDKTVK 1222 Score = 82.8 bits (203), Expect = 7e-16 Identities = 47/160 (29%), Positives = 78/160 (48%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 L H++ V +F +T+ G ED+ V LW + +L+G V SLSF Sbjct: 1190 LMTLTGHSAGVITVRFSP-DGQTIAAGSEDKTVKLWHRQDGKLLKTLNGHQDWVNSLSFS 1248 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 + + +A TIK+W I + K+V+T GH + ++ G AS S D +K+W Sbjct: 1249 PDGKTLASASADKTIKLWRIADGKLVKTLKGHNDSVWDVNFSSDGKAIASASRDNTIKLW 1308 Query: 480 DMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 + R + T+ GH+G + + F PD I S D++++ Sbjct: 1309 N-RHGIELETFTGHSGGVYAVNFLPDSNIIASASLDNTIR 1347 Score = 80.9 bits (198), Expect = 3e-15 Identities = 42/160 (26%), Positives = 77/160 (48%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 L+ H V F + L + D + LW +++L+G ++ V ++ F Sbjct: 1148 LKTITGHEQTVNNVYFSP-DGKNLASASSDHSIKLWDTTSGQLLMTLTGHSAGVITVRFS 1206 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 I AG+ T+K+W ++ K+++T GH+ SL P G AS S+D +K+W Sbjct: 1207 PDGQTIAAGSEDKTVKLWHRQDGKLLKTLNGHQDWVNSLSFSPDGKTLASASADKTIKLW 1266 Query: 480 DMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 + + + T +GH + + F+ DG+ I S D+++K Sbjct: 1267 RIADGKLVKTLKGHNDSVWDVNFSSDGKAIASASRDNTIK 1306 Score = 78.2 bits (191), Expect = 2e-14 Identities = 39/137 (28%), Positives = 69/137 (50%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 + T G D + LW + + +L G + +SF +I + A T+KIW + + Sbjct: 1378 IATAGADGNIQLWHSQDGSLLKTLPG-NKAIYGISFTPQGDLIASANADKTVKIWRVRDG 1436 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 K ++T GH + ++ P G AS S D +K+W++ + T +GHT + + F Sbjct: 1437 KALKTLIGHDNEVNKVNFSPDGKTLASASRDNTVKLWNVSDGKFKKTLKGHTDEVFWVSF 1496 Query: 549 TPDGRWIVSGGADSSVK 599 +PDG+ I S AD +++ Sbjct: 1497 SPDGKIIASASADKTIR 1513 Score = 73.2 bits (178), Expect = 5e-13 Identities = 35/137 (25%), Positives = 63/137 (45%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 + + D+ V +W V A+ +L G + V ++F + + + T+K+W++ + Sbjct: 1419 IASANADKTVKIWRVRDGKALKTLIGHDNEVNKVNFSPDGKTLASASRDNTVKLWNVSDG 1478 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 K +T GH + P G AS S+D +++WD I + H + + F Sbjct: 1479 KFKKTLKGHTDEVFWVSFSPDGKIIASASADKTIRLWDSFSGNLIKSLPAHNDLVYSVNF 1538 Query: 549 TPDGRWIVSGGADSSVK 599 PDG + S AD +VK Sbjct: 1539 NPDGSMLASTSADKTVK 1555 Score = 70.1 bits (170), Expect = 5e-12 Identities = 40/154 (25%), Positives = 71/154 (46%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMI 317 H +V F + + + D+ + LW + SL V S++F+ M+ Sbjct: 1487 HTDEVFWVSFSP-DGKIIASASADKTIRLWDSFSGNLIKSLPAHNDLVYSVNFNPDGSML 1545 Query: 318 GAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKR 497 + +A T+K+W + ++ TF+GH + S P G + AS S D +KIW + Sbjct: 1546 ASTSADKTVKLWRSHDGHLLHTFSGHSNVVYSSSFSPDGRYIASASEDKTVKIWQI-DGH 1604 Query: 498 CIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 + T H + F+PDG+ ++SG D++ K Sbjct: 1605 LLTTLPQHQAGVMSAIFSPDGKTLISGSLDTTTK 1638 Score = 67.4 bits (163), Expect = 3e-11 Identities = 36/114 (31%), Positives = 55/114 (48%) Frame = +3 Query: 258 LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGD 437 L G V S+S I +G+ TIK+W + ++ RT GH S+ P G Sbjct: 1068 LEGHKDGVISISISRDGQTIASGSLDKTIKLWS-RDGRLFRTLNGHEDAVYSVSFSPDGQ 1126 Query: 438 FFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 ASG SD +K+W + T GH ++ + F+PDG+ + S +D S+K Sbjct: 1127 TIASGGSDKTIKLWQTSDGTLLKTITGHEQTVNNVYFSPDGKNLASASSDHSIK 1180 Score = 63.5 bits (153), Expect = 4e-10 Identities = 36/139 (25%), Positives = 66/139 (47%) Frame = +3 Query: 183 RTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIE 362 +TL + D+ + LW + V +L G V ++F S I + + TIK+W+ Sbjct: 1252 KTLASASADKTIKLWRIADGKLVKTLKGHNDSVWDVNFSSDGKAIASASRDNTIKLWNRH 1311 Query: 363 EAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVL 542 ++ TFTGH +++ P + AS S D +++W + G++G + + Sbjct: 1312 GIEL-ETFTGHSGGVYAVNFLPDSNIIASASLDNTIRLWQRPLISPLEVLAGNSG-VYAV 1369 Query: 543 RFTPDGRWIVSGGADSSVK 599 F DG I + GAD +++ Sbjct: 1370 SFLHDGSIIATAGADGNIQ 1388 Score = 46.2 bits (108), Expect = 7e-05 Identities = 30/97 (30%), Positives = 44/97 (45%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L + D+ V LW + + SG ++ V S SF I + + T+KIW I+ Sbjct: 1545 LASTSADKTVKLWRSHDGHLLHTFSGHSNVVYSSSFSPDGRYIASASEDKTVKIWQID-G 1603 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 ++ T H++ S P G SGS DT KIW Sbjct: 1604 HLLTTLPQHQAGVMSAIFSPDGKTLISGSLDTTTKIW 1640
>TAF5_YEAST (P38129) Transcription initiation factor TFIID subunit 5| (TBP-associated factor 5) (TBP-associated factor 90 kDa) (TAFII-90) Length = 798 Score = 88.6 bits (218), Expect = 1e-17 Identities = 44/155 (28%), Positives = 75/155 (48%) Frame = +3 Query: 132 VAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEV 311 V H+ V F ++ L++G ED+ V LW++ TA++S G PV +SF Sbjct: 522 VGHSGTVYSTSFSP-DNKYLLSGSEDKTVRLWSMDTHTALVSYKGHNHPVWDVSFSPLGH 580 Query: 312 MIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRK 491 + T ++W + +R F GH ++ + HP G + +GSSD ++WD+ Sbjct: 581 YFATASHDQTARLWSCDHIYPLRIFAGHLNDVDCVSFHPNGCYVFTGSSDKTCRMWDVST 640 Query: 492 KRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 + + GHT + + PDGRW+ +G D + Sbjct: 641 GDSVRLFLGHTAPVISIAVCPDGRWLSTGSEDGII 675 Score = 69.7 bits (169), Expect = 6e-12 Identities = 37/136 (27%), Positives = 68/136 (50%), Gaps = 1/136 (0%) Frame = +3 Query: 195 TGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKV 374 T DQ LW+ + +G + V+ +SF + + G++ T ++WD+ Sbjct: 584 TASHDQTARLWSCDHIYPLRIFAGHLNDVDCVSFHPNGCYVFTGSSDKTCRMWDVSTGDS 643 Query: 375 VRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGH-TGRIDVLRFT 551 VR F GH + S+ P G + ++GS D + +WD+ + + +GH I L ++ Sbjct: 644 VRLFLGHTAPVISIAVCPDGRWLSTGSEDGIINVWDIGTGKRLKQMRGHGKNAIYSLSYS 703 Query: 552 PDGRWIVSGGADSSVK 599 +G ++SGGAD +V+ Sbjct: 704 KEGNVLISGGADHTVR 719 Score = 68.2 bits (165), Expect = 2e-11 Identities = 38/127 (29%), Positives = 59/127 (46%), Gaps = 1/127 (0%) Frame = +3 Query: 114 YKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLS 293 Y L+ F H +DV C F + TG D+ +W V +V G T+PV S++ Sbjct: 600 YPLRIFAGHLNDVDCVSFHPNGCY-VFTGSSDKTCRMWDVSTGDSVRLFLGHTAPVISIA 658 Query: 294 FDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCA-SLDSHPFGDFFASGSSDTNM 470 + G+ G I +WDI K ++ GH N SL G+ SG +D + Sbjct: 659 VCPDGRWLSTGSEDGIINVWDIGTGKRLKQMRGHGKNAIYSLSYSKEGNVLISGGADHTV 718 Query: 471 KIWDMRK 491 ++WD++K Sbjct: 719 RVWDLKK 725 Score = 61.2 bits (147), Expect = 2e-09 Identities = 35/168 (20%), Positives = 71/168 (42%), Gaps = 17/168 (10%) Frame = +3 Query: 147 DVTCAKFGKRTSRTLITGGEDQKVNLWAV-----GKPTAVLS------------LSGLTS 275 D++C F R G +D + +W++ P L+ L G + Sbjct: 468 DMSCLDFSD-DCRIAAAGFQDSYIKIWSLDGSSLNNPNIALNNNDKDEDPTCKTLVGHSG 526 Query: 276 PVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGS 455 V S SF + +G+ T+++W ++ + ++ GH + P G +FA+ S Sbjct: 527 TVYSTSFSPDNKYLLSGSEDKTVRLWSMDTHTALVSYKGHNHPVWDVSFSPLGHYFATAS 586 Query: 456 SDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 D ++W + + GH +D + F P+G ++ +G +D + + Sbjct: 587 HDQTARLWSCDHIYPLRIFAGHLNDVDCVSFHPNGCYVFTGSSDKTCR 634 Score = 40.0 bits (92), Expect = 0.005 Identities = 19/63 (30%), Positives = 36/63 (57%), Gaps = 1/63 (1%) Frame = +3 Query: 183 RTLITGGEDQKVNLWAVGKPTAVLSLSGL-TSPVESLSFDSSEVMIGAGAASGTIKIWDI 359 R L TG ED +N+W +G + + G + + SLS+ ++ +G A T+++WD+ Sbjct: 664 RWLSTGSEDGIINVWDIGTGKRLKQMRGHGKNAIYSLSYSKEGNVLISGGADHTVRVWDL 723 Query: 360 EEA 368 ++A Sbjct: 724 KKA 726
>LIS1_BOVIN (P43033) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 87.8 bits (216), Expect = 2e-17 Identities = 49/154 (31%), Positives = 78/154 (50%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMI 317 H S VT F S +++ ED + +W +L G T VE +SFD S ++ Sbjct: 106 HRSPVTRVIFHPVFS-VMVSASEDATIKVWDYETGDFERTLKGHTDSVEDISFDHSGKLL 164 Query: 318 GAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKR 497 + +A TIK+WD + + +RT GH N +S+ P GD S S D +K+W+++ Sbjct: 165 ASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGY 224 Query: 498 CIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 C+ T+ GH + ++R DG I S D +V+ Sbjct: 225 CVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVR 258 Score = 73.9 bits (180), Expect = 3e-13 Identities = 40/133 (30%), Positives = 62/133 (46%) Frame = +3 Query: 201 GEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVR 380 G+ + W + +P +LSG SPV + F ++ + + TIK+WD E R Sbjct: 85 GQKRDPKEW-IPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFER 143 Query: 381 TFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDG 560 T GH + + G AS S+D +K+WD + CI T GH + + P+G Sbjct: 144 TLKGHTDSVEDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNG 203 Query: 561 RWIVSGGADSSVK 599 IVS D ++K Sbjct: 204 DHIVSASRDKTIK 216 Score = 62.8 bits (151), Expect = 7e-10 Identities = 47/183 (25%), Positives = 72/183 (39%), Gaps = 21/183 (11%) Frame = +3 Query: 114 YKLQEFVAHASDVTCAKFGKRTSRTLITG-GEDQKVNLWAVGKPTAVLSLSGLTSPVESL 290 Y ++ F H V + TLI DQ V +W V L VE + Sbjct: 224 YCVKTFTGHREWVRMVR--PNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECI 281 Query: 291 SF--DSSEVMIG------------------AGAASGTIKIWDIEEAKVVRTFTGHRSNCA 410 S+ +SS I +G+ TIK+WD+ + T GH + Sbjct: 282 SWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVR 341 Query: 411 SLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADS 590 + H G F S + D +++WD + KRC+ T H + L F ++V+G D Sbjct: 342 GVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQ 401 Query: 591 SVK 599 +VK Sbjct: 402 TVK 404 Score = 59.3 bits (142), Expect = 8e-09 Identities = 27/100 (27%), Positives = 50/100 (50%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L++G D+ + +W V +++L G + V + F S I + A T+++WD + Sbjct: 310 LLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNK 369 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMR 488 + ++T H SLD H + +GS D +K+W+ R Sbjct: 370 RCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 409 Score = 54.7 bits (130), Expect = 2e-07 Identities = 29/130 (22%), Positives = 60/130 (46%) Frame = +3 Query: 177 TSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWD 356 + + L + D + LW + ++ G V S++ + I + + TIK+W+ Sbjct: 160 SGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWE 219 Query: 357 IEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRID 536 ++ V+TFTGHR + + G AS S+D +++W + K C + H ++ Sbjct: 220 VQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVE 279 Query: 537 VLRFTPDGRW 566 + + P+ + Sbjct: 280 CISWAPESSY 289
>WD51A_HUMAN (Q8NBT0) WD-repeat protein 51A| Length = 407 Score = 87.8 bits (216), Expect = 2e-17 Identities = 49/166 (29%), Positives = 78/166 (46%) Frame = +3 Query: 99 ATKRAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSP 278 AT R L H + V CAKF R +++ +D+ V LW V S Sbjct: 131 ATHRQKFLFSLSQHINWVRCAKFSP-DGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGF 189 Query: 279 VESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSS 458 V + F S I A T+K+WD+ ++++ + H + L HP G++ + SS Sbjct: 190 VTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLITASS 249 Query: 459 DTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 D+ +KI D+ + R ++T GH G + F+ G + SGG+D V Sbjct: 250 DSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQV 295 Score = 84.7 bits (208), Expect = 2e-16 Identities = 43/157 (27%), Positives = 77/157 (49%) Frame = +3 Query: 129 FVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSE 308 F AH + V F ++ +T +D+ V +WA + + SLS + V F Sbjct: 99 FRAHTATVRSVHFCS-DGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDG 157 Query: 309 VMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMR 488 +I + + T+K+WD + V ++ H +D HP G A+ D +K+WD+R Sbjct: 158 RLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVR 217 Query: 489 KKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 R + YQ H+ ++ L F P G ++++ +DS++K Sbjct: 218 THRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLK 254 Score = 55.8 bits (133), Expect = 9e-08 Identities = 29/120 (24%), Positives = 51/120 (42%) Frame = +3 Query: 240 PTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLD 419 P+ G V + F + + +G+ + +W ++ FTGH+ ++ Sbjct: 9 PSLERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVN 68 Query: 420 SHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 P G ASGS D ++IW K ++ HT + + F DG+ V+ D +VK Sbjct: 69 FSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVK 128 Score = 50.4 bits (119), Expect = 4e-06 Identities = 30/120 (25%), Positives = 53/120 (44%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 + + H VT F + + G D V +W V + ++ V LSF Sbjct: 180 VHSYCEHGGFVTYVDFHP-SGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFH 238 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 S + ++ T+KI D+ E +++ T GH+ ++ G++FASG SD + +W Sbjct: 239 PSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVW 298 Score = 48.9 bits (115), Expect = 1e-05 Identities = 23/80 (28%), Positives = 39/80 (48%) Frame = +3 Query: 360 EEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDV 539 E+ + R F GHR +D ASGS D+ + +W M+ + + + GH + Sbjct: 7 EDPSLERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTC 66 Query: 540 LRFTPDGRWIVSGGADSSVK 599 + F+P G + SG D +V+ Sbjct: 67 VNFSPSGHLLASGSRDKTVR 86
>TAF5_HUMAN (Q15542) Transcription initiation factor TFIID subunit 5| (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100) Length = 800 Score = 87.0 bits (214), Expect = 4e-17 Identities = 42/136 (30%), Positives = 70/136 (51%) Frame = +3 Query: 192 ITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAK 371 ++GG D+ LWA + +G + V F + + G+A T+++WD+ Sbjct: 601 VSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGN 660 Query: 372 VVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFT 551 VR FTGH+ SL P G F A+G++D + +WD+ + +GHT + LRF+ Sbjct: 661 CVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFS 720 Query: 552 PDGRWIVSGGADSSVK 599 DG + SG D++V+ Sbjct: 721 RDGEILASGSMDNTVR 736 Score = 86.3 bits (212), Expect = 6e-17 Identities = 46/167 (27%), Positives = 79/167 (47%) Frame = +3 Query: 96 MATKRAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTS 275 M K A +L+ H+ V A F + L++ ED V LW++ T ++ G Sbjct: 528 MDEKTASELKILYGHSGPVYGASFSPDRNY-LLSSSEDGTVRLWSLQTFTCLVGYKGHNY 586 Query: 276 PVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGS 455 PV F +G ++W + + +R F GH ++ HP ++ A+GS Sbjct: 587 PVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGS 646 Query: 456 SDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 +D +++WD+ C+ + GH G I L F+P+GR++ +G D V Sbjct: 647 ADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRV 693 Score = 77.8 bits (190), Expect = 2e-14 Identities = 43/131 (32%), Positives = 60/131 (45%) Frame = +3 Query: 99 ATKRAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSP 278 AT L+ F H +DV C +F S + TG D+ V LW V V +G P Sbjct: 613 ATDHYQPLRIFAGHLADVNCTRFHPN-SNYVATGSADRTVRLWDVLNGNCVRIFTGHKGP 671 Query: 279 VESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSS 458 + SL+F + + GA G + +WDI +V GH SL G+ ASGS Sbjct: 672 IHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSM 731 Query: 459 DTNMKIWDMRK 491 D +++WD K Sbjct: 732 DNTVRLWDAIK 742 Score = 48.1 bits (113), Expect = 2e-05 Identities = 35/135 (25%), Positives = 62/135 (45%), Gaps = 1/135 (0%) Frame = +3 Query: 186 TLITGG-EDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIE 362 +LI GG D V +W+V P + S+ S + + +S +V+ +I D + Sbjct: 483 SLIAGGFADSTVRVWSV-TPKKLRSVKQ-ASDLSLIDKESDDVLE---------RIMDEK 531 Query: 363 EAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVL 542 A ++ GH P ++ S S D +++W ++ C+ Y+GH + Sbjct: 532 TASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDT 591 Query: 543 RFTPDGRWIVSGGAD 587 +F+P G + VSGG D Sbjct: 592 QFSPYGYYFVSGGHD 606 Score = 34.7 bits (78), Expect = 0.22 Identities = 28/119 (23%), Positives = 53/119 (44%) Frame = +3 Query: 243 TAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDS 422 T + + GLT+ ++ DSS +I G A T+++W + K+ S+ + +D Sbjct: 465 TFLNAYQGLTAV--DVTDDSS--LIAGGFADSTVRVWSVTPKKL--RSVKQASDLSLIDK 518 Query: 423 HPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 S D +I D + + GH+G + F+PD +++S D +V+ Sbjct: 519 E---------SDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVR 568
>LIS1_RAT (P63004) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 86.7 bits (213), Expect = 5e-17 Identities = 48/154 (31%), Positives = 78/154 (50%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMI 317 H S VT F S +++ ED + +W +L G T V+ +SFD S ++ Sbjct: 106 HRSPVTRVIFHPVFS-VMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLL 164 Query: 318 GAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKR 497 + +A TIK+WD + + +RT GH N +S+ P GD S S D +K+W+++ Sbjct: 165 ASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGY 224 Query: 498 CIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 C+ T+ GH + ++R DG I S D +V+ Sbjct: 225 CVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVR 258 Score = 73.9 bits (180), Expect = 3e-13 Identities = 40/133 (30%), Positives = 62/133 (46%) Frame = +3 Query: 201 GEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVR 380 G+ + W + +P +LSG SPV + F ++ + + TIK+WD E R Sbjct: 85 GQKRDPKEW-IPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFER 143 Query: 381 TFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDG 560 T GH + + G AS S+D +K+WD + CI T GH + + P+G Sbjct: 144 TLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNG 203 Query: 561 RWIVSGGADSSVK 599 IVS D ++K Sbjct: 204 DHIVSASRDKTIK 216 Score = 62.8 bits (151), Expect = 7e-10 Identities = 47/183 (25%), Positives = 72/183 (39%), Gaps = 21/183 (11%) Frame = +3 Query: 114 YKLQEFVAHASDVTCAKFGKRTSRTLITG-GEDQKVNLWAVGKPTAVLSLSGLTSPVESL 290 Y ++ F H V + TLI DQ V +W V L VE + Sbjct: 224 YCVKTFTGHREWVRMVR--PNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECI 281 Query: 291 SF--DSSEVMIG------------------AGAASGTIKIWDIEEAKVVRTFTGHRSNCA 410 S+ +SS I +G+ TIK+WD+ + T GH + Sbjct: 282 SWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVR 341 Query: 411 SLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADS 590 + H G F S + D +++WD + KRC+ T H + L F ++V+G D Sbjct: 342 GVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQ 401 Query: 591 SVK 599 +VK Sbjct: 402 TVK 404 Score = 59.3 bits (142), Expect = 8e-09 Identities = 27/100 (27%), Positives = 50/100 (50%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L++G D+ + +W V +++L G + V + F S I + A T+++WD + Sbjct: 310 LLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNK 369 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMR 488 + ++T H SLD H + +GS D +K+W+ R Sbjct: 370 RCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 409 Score = 54.7 bits (130), Expect = 2e-07 Identities = 29/130 (22%), Positives = 60/130 (46%) Frame = +3 Query: 177 TSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWD 356 + + L + D + LW + ++ G V S++ + I + + TIK+W+ Sbjct: 160 SGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWE 219 Query: 357 IEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRID 536 ++ V+TFTGHR + + G AS S+D +++W + K C + H ++ Sbjct: 220 VQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVE 279 Query: 537 VLRFTPDGRW 566 + + P+ + Sbjct: 280 CISWAPESSY 289
>LIS1_PANTR (Q5IS43) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 86.7 bits (213), Expect = 5e-17 Identities = 48/154 (31%), Positives = 78/154 (50%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMI 317 H S VT F S +++ ED + +W +L G T V+ +SFD S ++ Sbjct: 106 HRSPVTRVIFHPVFS-VMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLL 164 Query: 318 GAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKR 497 + +A TIK+WD + + +RT GH N +S+ P GD S S D +K+W+++ Sbjct: 165 ASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGY 224 Query: 498 CIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 C+ T+ GH + ++R DG I S D +V+ Sbjct: 225 CVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVR 258 Score = 73.9 bits (180), Expect = 3e-13 Identities = 40/133 (30%), Positives = 62/133 (46%) Frame = +3 Query: 201 GEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVR 380 G+ + W + +P +LSG SPV + F ++ + + TIK+WD E R Sbjct: 85 GQKRDPKEW-IPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFER 143 Query: 381 TFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDG 560 T GH + + G AS S+D +K+WD + CI T GH + + P+G Sbjct: 144 TLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNG 203 Query: 561 RWIVSGGADSSVK 599 IVS D ++K Sbjct: 204 DHIVSASRDKTIK 216 Score = 61.6 bits (148), Expect = 2e-09 Identities = 47/183 (25%), Positives = 72/183 (39%), Gaps = 21/183 (11%) Frame = +3 Query: 114 YKLQEFVAHASDVTCAKFGKRTSRTLITG-GEDQKVNLWAVGKPTAVLSLSGLTSPVESL 290 Y ++ F H V + TLI DQ V +W V L VE + Sbjct: 224 YCVKTFTGHREWVRMVR--PNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECI 281 Query: 291 SF--DSSEVMIG------------------AGAASGTIKIWDIEEAKVVRTFTGHRSNCA 410 S+ +SS I +G+ TIK+WD+ + T GH + Sbjct: 282 SWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVR 341 Query: 411 SLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADS 590 + H G F S + D +++WD + KRC+ T H + L F ++V+G D Sbjct: 342 GVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGFVDQ 401 Query: 591 SVK 599 +VK Sbjct: 402 TVK 404 Score = 57.0 bits (136), Expect = 4e-08 Identities = 26/100 (26%), Positives = 49/100 (49%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L++G D+ + +W V +++L G + V + F S I + A T+++WD + Sbjct: 310 LLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNK 369 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMR 488 + ++T H SLD H + +G D +K+W+ R Sbjct: 370 RCMKTLNAHEHFVTSLDFHKTAPYVVTGFVDQTVKVWECR 409 Score = 54.7 bits (130), Expect = 2e-07 Identities = 29/130 (22%), Positives = 60/130 (46%) Frame = +3 Query: 177 TSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWD 356 + + L + D + LW + ++ G V S++ + I + + TIK+W+ Sbjct: 160 SGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWE 219 Query: 357 IEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRID 536 ++ V+TFTGHR + + G AS S+D +++W + K C + H ++ Sbjct: 220 VQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVE 279 Query: 537 VLRFTPDGRW 566 + + P+ + Sbjct: 280 CISWAPESSY 289
>LIS1_MOUSE (P63005) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 86.7 bits (213), Expect = 5e-17 Identities = 48/154 (31%), Positives = 78/154 (50%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMI 317 H S VT F S +++ ED + +W +L G T V+ +SFD S ++ Sbjct: 106 HRSPVTRVIFHPVFS-VMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLL 164 Query: 318 GAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKR 497 + +A TIK+WD + + +RT GH N +S+ P GD S S D +K+W+++ Sbjct: 165 ASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGY 224 Query: 498 CIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 C+ T+ GH + ++R DG I S D +V+ Sbjct: 225 CVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVR 258 Score = 73.9 bits (180), Expect = 3e-13 Identities = 40/133 (30%), Positives = 62/133 (46%) Frame = +3 Query: 201 GEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVR 380 G+ + W + +P +LSG SPV + F ++ + + TIK+WD E R Sbjct: 85 GQKRDPKEW-IPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFER 143 Query: 381 TFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDG 560 T GH + + G AS S+D +K+WD + CI T GH + + P+G Sbjct: 144 TLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNG 203 Query: 561 RWIVSGGADSSVK 599 IVS D ++K Sbjct: 204 DHIVSASRDKTIK 216 Score = 62.8 bits (151), Expect = 7e-10 Identities = 47/183 (25%), Positives = 72/183 (39%), Gaps = 21/183 (11%) Frame = +3 Query: 114 YKLQEFVAHASDVTCAKFGKRTSRTLITG-GEDQKVNLWAVGKPTAVLSLSGLTSPVESL 290 Y ++ F H V + TLI DQ V +W V L VE + Sbjct: 224 YCVKTFTGHREWVRMVR--PNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECI 281 Query: 291 SF--DSSEVMIG------------------AGAASGTIKIWDIEEAKVVRTFTGHRSNCA 410 S+ +SS I +G+ TIK+WD+ + T GH + Sbjct: 282 SWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVR 341 Query: 411 SLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADS 590 + H G F S + D +++WD + KRC+ T H + L F ++V+G D Sbjct: 342 GVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQ 401 Query: 591 SVK 599 +VK Sbjct: 402 TVK 404 Score = 59.3 bits (142), Expect = 8e-09 Identities = 27/100 (27%), Positives = 50/100 (50%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L++G D+ + +W V +++L G + V + F S I + A T+++WD + Sbjct: 310 LLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNK 369 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMR 488 + ++T H SLD H + +GS D +K+W+ R Sbjct: 370 RCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 409 Score = 54.7 bits (130), Expect = 2e-07 Identities = 29/130 (22%), Positives = 60/130 (46%) Frame = +3 Query: 177 TSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWD 356 + + L + D + LW + ++ G V S++ + I + + TIK+W+ Sbjct: 160 SGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWE 219 Query: 357 IEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRID 536 ++ V+TFTGHR + + G AS S+D +++W + K C + H ++ Sbjct: 220 VQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVE 279 Query: 537 VLRFTPDGRW 566 + + P+ + Sbjct: 280 CISWAPESSY 289
>LIS1_HUMAN (P43034) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 86.7 bits (213), Expect = 5e-17 Identities = 48/154 (31%), Positives = 78/154 (50%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMI 317 H S VT F S +++ ED + +W +L G T V+ +SFD S ++ Sbjct: 106 HRSPVTRVIFHPVFS-VMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLL 164 Query: 318 GAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKR 497 + +A TIK+WD + + +RT GH N +S+ P GD S S D +K+W+++ Sbjct: 165 ASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGY 224 Query: 498 CIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 C+ T+ GH + ++R DG I S D +V+ Sbjct: 225 CVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVR 258 Score = 73.9 bits (180), Expect = 3e-13 Identities = 40/133 (30%), Positives = 62/133 (46%) Frame = +3 Query: 201 GEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVR 380 G+ + W + +P +LSG SPV + F ++ + + TIK+WD E R Sbjct: 85 GQKRDPKEW-IPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFER 143 Query: 381 TFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDG 560 T GH + + G AS S+D +K+WD + CI T GH + + P+G Sbjct: 144 TLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNG 203 Query: 561 RWIVSGGADSSVK 599 IVS D ++K Sbjct: 204 DHIVSASRDKTIK 216 Score = 62.8 bits (151), Expect = 7e-10 Identities = 47/183 (25%), Positives = 72/183 (39%), Gaps = 21/183 (11%) Frame = +3 Query: 114 YKLQEFVAHASDVTCAKFGKRTSRTLITG-GEDQKVNLWAVGKPTAVLSLSGLTSPVESL 290 Y ++ F H V + TLI DQ V +W V L VE + Sbjct: 224 YCVKTFTGHREWVRMVR--PNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECI 281 Query: 291 SF--DSSEVMIG------------------AGAASGTIKIWDIEEAKVVRTFTGHRSNCA 410 S+ +SS I +G+ TIK+WD+ + T GH + Sbjct: 282 SWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVR 341 Query: 411 SLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADS 590 + H G F S + D +++WD + KRC+ T H + L F ++V+G D Sbjct: 342 GVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQ 401 Query: 591 SVK 599 +VK Sbjct: 402 TVK 404 Score = 59.3 bits (142), Expect = 8e-09 Identities = 27/100 (27%), Positives = 50/100 (50%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L++G D+ + +W V +++L G + V + F S I + A T+++WD + Sbjct: 310 LLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNK 369 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMR 488 + ++T H SLD H + +GS D +K+W+ R Sbjct: 370 RCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 409 Score = 54.7 bits (130), Expect = 2e-07 Identities = 29/130 (22%), Positives = 60/130 (46%) Frame = +3 Query: 177 TSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWD 356 + + L + D + LW + ++ G V S++ + I + + TIK+W+ Sbjct: 160 SGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWE 219 Query: 357 IEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRID 536 ++ V+TFTGHR + + G AS S+D +++W + K C + H ++ Sbjct: 220 VQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVE 279 Query: 537 VLRFTPDGRW 566 + + P+ + Sbjct: 280 CISWAPESSY 289
>WD51A_BOVIN (Q2TBP4) WD-repeat protein 51A| Length = 407 Score = 86.7 bits (213), Expect = 5e-17 Identities = 48/166 (28%), Positives = 79/166 (47%) Frame = +3 Query: 99 ATKRAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSP 278 +T R L H + V CAKF R +++ +D+ V LW V S Sbjct: 131 STHRQKFLFSLSQHINWVRCAKFSP-DGRLIVSASDDKTVKLWDKTSRECVHSYCEHGGF 189 Query: 279 VESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSS 458 V + F S I A T+K+WD+ ++++ + H + +L HP G++ + SS Sbjct: 190 VTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNALSFHPSGNYLVTASS 249 Query: 459 DTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 D+ +KI D+ + R ++T GH G + F+ G + SGG+D V Sbjct: 250 DSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQV 295 Score = 84.7 bits (208), Expect = 2e-16 Identities = 43/157 (27%), Positives = 77/157 (49%) Frame = +3 Query: 129 FVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSE 308 F AH + V F ++ +T +D+ V +W+ + + SLS + V F Sbjct: 99 FRAHTATVRSVHFCS-DGQSFVTASDDKTVKVWSTHRQKFLFSLSQHINWVRCAKFSPDG 157 Query: 309 VMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMR 488 +I + + T+K+WD + V ++ H +D HP G A+ D +K+WD+R Sbjct: 158 RLIVSASDDKTVKLWDKTSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVR 217 Query: 489 KKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 R + YQ H+ ++ L F P G ++V+ +DS++K Sbjct: 218 THRLLQHYQLHSAAVNALSFHPSGNYLVTASSDSTLK 254 Score = 55.5 bits (132), Expect = 1e-07 Identities = 29/120 (24%), Positives = 51/120 (42%) Frame = +3 Query: 240 PTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLD 419 P+ G V S+ F + + +G+ + +W ++ F GH+ ++ Sbjct: 9 PSLERHFKGHRDAVTSVDFSLNTKQLASGSMDSCLMVWHMKPQTRAYRFAGHKDAVTCVN 68 Query: 420 SHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 P G ASGS D ++IW K ++ HT + + F DG+ V+ D +VK Sbjct: 69 FSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVK 128 Score = 51.2 bits (121), Expect = 2e-06 Identities = 30/120 (25%), Positives = 54/120 (45%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 + + H VT F + + G D V +W V + ++ V +LSF Sbjct: 180 VHSYCEHGGFVTYVDFHP-SGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNALSFH 238 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 S + ++ T+KI D+ E +++ T GH+ ++ G++FASG SD + +W Sbjct: 239 PSGNYLVTASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVW 298 Score = 50.8 bits (120), Expect = 3e-06 Identities = 24/80 (30%), Positives = 40/80 (50%) Frame = +3 Query: 360 EEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDV 539 E+ + R F GHR S+D ASGS D+ + +W M+ + + + GH + Sbjct: 7 EDPSLERHFKGHRDAVTSVDFSLNTKQLASGSMDSCLMVWHMKPQTRAYRFAGHKDAVTC 66 Query: 540 LRFTPDGRWIVSGGADSSVK 599 + F+P G + SG D +V+ Sbjct: 67 VNFSPSGHLLASGSRDKTVR 86
>TAF5_MOUSE (Q8C092) Transcription initiation factor TFIID subunit 5| (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100) Length = 801 Score = 86.3 bits (212), Expect = 6e-17 Identities = 46/167 (27%), Positives = 79/167 (47%) Frame = +3 Query: 96 MATKRAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTS 275 M K A +L+ H+ V A F + L++ ED V LW++ T ++ G Sbjct: 529 MDEKTASELKILYGHSGPVYGASFSPDRNY-LLSSSEDGTVRLWSLQTFTCLVGYKGHNY 587 Query: 276 PVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGS 455 PV F +G ++W + + +R F GH ++ HP ++ A+GS Sbjct: 588 PVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRYHPNSNYVATGS 647 Query: 456 SDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 +D +++WD+ C+ + GH G I L F+P+GR++ +G D V Sbjct: 648 ADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRV 694 Score = 85.9 bits (211), Expect = 8e-17 Identities = 41/136 (30%), Positives = 70/136 (51%) Frame = +3 Query: 192 ITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAK 371 ++GG D+ LWA + +G + V + + + G+A T+++WD+ Sbjct: 602 VSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRYHPNSNYVATGSADRTVRLWDVLNGN 661 Query: 372 VVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFT 551 VR FTGH+ SL P G F A+G++D + +WD+ + +GHT + LRF+ Sbjct: 662 CVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFS 721 Query: 552 PDGRWIVSGGADSSVK 599 DG + SG D++V+ Sbjct: 722 RDGEILASGSMDNTVR 737 Score = 76.6 bits (187), Expect = 5e-14 Identities = 42/131 (32%), Positives = 60/131 (45%) Frame = +3 Query: 99 ATKRAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSP 278 AT L+ F H +DV C ++ S + TG D+ V LW V V +G P Sbjct: 614 ATDHYQPLRIFAGHLADVNCTRYHPN-SNYVATGSADRTVRLWDVLNGNCVRIFTGHKGP 672 Query: 279 VESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSS 458 + SL+F + + GA G + +WDI +V GH SL G+ ASGS Sbjct: 673 IHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSM 732 Query: 459 DTNMKIWDMRK 491 D +++WD K Sbjct: 733 DNTVRLWDAVK 743 Score = 48.1 bits (113), Expect = 2e-05 Identities = 35/135 (25%), Positives = 62/135 (45%), Gaps = 1/135 (0%) Frame = +3 Query: 186 TLITGG-EDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIE 362 +LI GG D V +W+V P + S+ S + + +S +V+ +I D + Sbjct: 484 SLIAGGFADSTVRVWSV-TPKKLRSVKQ-ASDLSLIDKESDDVLE---------RIMDEK 532 Query: 363 EAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVL 542 A ++ GH P ++ S S D +++W ++ C+ Y+GH + Sbjct: 533 TASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDT 592 Query: 543 RFTPDGRWIVSGGAD 587 +F+P G + VSGG D Sbjct: 593 QFSPYGYYFVSGGHD 607 Score = 34.7 bits (78), Expect = 0.22 Identities = 28/119 (23%), Positives = 53/119 (44%) Frame = +3 Query: 243 TAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDS 422 T + + GLT+ ++ DSS +I G A T+++W + K+ S+ + +D Sbjct: 466 TFLNAYQGLTAV--DVTDDSS--LIAGGFADSTVRVWSVTPKKL--RSVKQASDLSLIDK 519 Query: 423 HPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 S D +I D + + GH+G + F+PD +++S D +V+ Sbjct: 520 E---------SDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVR 569
>LIS1_MACFA (Q8HXX0) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 85.9 bits (211), Expect = 8e-17 Identities = 48/154 (31%), Positives = 78/154 (50%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMI 317 H S VT F S +++ ED + +W +L G T V+ +SFD S ++ Sbjct: 106 HRSPVTRVIFHPVFS-VMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLL 164 Query: 318 GAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKR 497 + +A TIK+WD + + +RT GH N +S+ P GD S S D +K+W+++ Sbjct: 165 TSCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHLVSASRDKTIKMWEVQTGY 224 Query: 498 CIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 C+ T+ GH + ++R DG I S D +V+ Sbjct: 225 CVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVR 258 Score = 71.6 bits (174), Expect = 2e-12 Identities = 38/133 (28%), Positives = 61/133 (45%) Frame = +3 Query: 201 GEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVR 380 G+ + W + +P +LSG SPV + F ++ + + TIK+WD E R Sbjct: 85 GQKRDPKEW-IPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFER 143 Query: 381 TFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDG 560 T GH + + G S S+D +K+WD + CI T GH + + P+G Sbjct: 144 TLKGHTDSVQDISFDHSGKLLTSCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNG 203 Query: 561 RWIVSGGADSSVK 599 +VS D ++K Sbjct: 204 DHLVSASRDKTIK 216 Score = 62.8 bits (151), Expect = 7e-10 Identities = 47/183 (25%), Positives = 72/183 (39%), Gaps = 21/183 (11%) Frame = +3 Query: 114 YKLQEFVAHASDVTCAKFGKRTSRTLITG-GEDQKVNLWAVGKPTAVLSLSGLTSPVESL 290 Y ++ F H V + TLI DQ V +W V L VE + Sbjct: 224 YCVKTFTGHREWVRMVR--PNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECI 281 Query: 291 SF--DSSEVMIG------------------AGAASGTIKIWDIEEAKVVRTFTGHRSNCA 410 S+ +SS I +G+ TIK+WD+ + T GH + Sbjct: 282 SWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVR 341 Query: 411 SLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADS 590 + H G F S + D +++WD + KRC+ T H + L F ++V+G D Sbjct: 342 GVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQ 401 Query: 591 SVK 599 +VK Sbjct: 402 TVK 404 Score = 59.3 bits (142), Expect = 8e-09 Identities = 27/100 (27%), Positives = 50/100 (50%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L++G D+ + +W V +++L G + V + F S I + A T+++WD + Sbjct: 310 LLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNK 369 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMR 488 + ++T H SLD H + +GS D +K+W+ R Sbjct: 370 RCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 409 Score = 53.9 bits (128), Expect = 3e-07 Identities = 28/130 (21%), Positives = 60/130 (46%) Frame = +3 Query: 177 TSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWD 356 + + L + D + LW + ++ G V S++ + + + + TIK+W+ Sbjct: 160 SGKLLTSCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHLVSASRDKTIKMWE 219 Query: 357 IEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRID 536 ++ V+TFTGHR + + G AS S+D +++W + K C + H ++ Sbjct: 220 VQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVE 279 Query: 537 VLRFTPDGRW 566 + + P+ + Sbjct: 280 CISWAPESSY 289
>PRP46_CRYNE (Q5KDR4) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 473 Score = 85.5 bits (210), Expect = 1e-16 Identities = 43/135 (31%), Positives = 68/135 (50%) Frame = +3 Query: 195 TGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKV 374 TG D+ + +W + LSL+G S + L+ + + A +K WD+E KV Sbjct: 199 TGAGDRVIKIWDLASGELKLSLTGHISTIRGLAVSDRHPYLFSCAEDKMVKCWDLETNKV 258 Query: 375 VRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTP 554 +R + GH S SL HP D +G D ++++WDMR + I T GHT + ++ Sbjct: 259 IRHYHGHFSGVYSLSVHPTLDVLVTGGRDASVRVWDMRTRANIFTLTGHTSTVGDVKTQD 318 Query: 555 DGRWIVSGGADSSVK 599 I+SG DS+V+ Sbjct: 319 SDPQIISGSMDSTVR 333 Score = 72.8 bits (177), Expect = 7e-13 Identities = 41/139 (29%), Positives = 69/139 (49%), Gaps = 1/139 (0%) Frame = +3 Query: 177 TSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWD 356 T L+TGG D V +W + + +L+G TS V + S+ I +G+ T+++WD Sbjct: 277 TLDVLVTGGRDASVRVWDMRTRANIFTLTGHTSTVGDVKTQDSDPQIISGSMDSTVRLWD 336 Query: 357 IEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSS-DTNMKIWDMRKKRCIHTYQGHTGRI 533 + K + T T H+ + +L HP FAS SS N+K W + ++ + GH I Sbjct: 337 LAAGKCMNTLTHHKKSVRALAIHPTEYSFASASSGGNNIKKWKCPEGIFVNNFVGHEAII 396 Query: 534 DVLRFTPDGRWIVSGGADS 590 + L + ++ GAD+ Sbjct: 397 NTLSINSEN--VLFSGADN 413 Score = 60.1 bits (144), Expect = 5e-09 Identities = 36/117 (30%), Positives = 54/117 (46%), Gaps = 3/117 (2%) Frame = +3 Query: 258 LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASL---DSHP 428 +SG V +++ D GA IKIWD+ ++ + TGH S L D HP Sbjct: 178 ISGHMGWVRAVAMDPGNQWFATGAGDRVIKIWDLASGELKLSLTGHISTIRGLAVSDRHP 237 Query: 429 FGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 + S + D +K WD+ + I Y GH + L P +V+GG D+SV+ Sbjct: 238 ---YLFSCAEDKMVKCWDLETNKVIRHYHGHFSGVYSLSVHPTLDVLVTGGRDASVR 291 Score = 57.8 bits (138), Expect = 2e-08 Identities = 30/122 (24%), Positives = 54/122 (44%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L + ED+ V W + + G S V SLS + ++ G ++++WD+ Sbjct: 239 LFSCAEDKMVKCWDLETNKVIRHYHGHFSGVYSLSVHPTLDVLVTGGRDASVRVWDMRTR 298 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 + T TGH S + + SGS D+ +++WD+ +C++T H + L Sbjct: 299 ANIFTLTGHTSTVGDVKTQDSDPQIISGSMDSTVRLWDLAAGKCMNTLTHHKKSVRALAI 358 Query: 549 TP 554 P Sbjct: 359 HP 360 Score = 44.3 bits (103), Expect = 3e-04 Identities = 35/148 (23%), Positives = 63/148 (42%), Gaps = 11/148 (7%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGT-IKIWDIEE 365 +I+G D V LW + + +L+ V +L+ +E + ++ G IK W E Sbjct: 323 IISGSMDSTVRLWDLAAGKCMNTLTHHKKSVRALAIHPTEYSFASASSGGNNIKKWKCPE 382 Query: 366 AKVVRTFTGHRS--NCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQG--HTGRI 533 V F GH + N S++S + SG+ + + +WD + + G + Sbjct: 383 GIFVNNFVGHEAIINTLSINSE---NVLFSGADNGTLTLWDYKTGLPFQHLKDIPQPGSL 439 Query: 534 DV------LRFTPDGRWIVSGGADSSVK 599 D F G +++GGAD ++K Sbjct: 440 DAEAGVFCSTFDKTGTRLITGGADKTIK 467 Score = 37.7 bits (86), Expect = 0.026 Identities = 22/79 (27%), Positives = 35/79 (44%) Frame = +3 Query: 363 EAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVL 542 E K+ R +GH ++ P +FA+G+ D +KIWD+ + GH I L Sbjct: 171 EWKLTRVISGHMGWVRAVAMDPGNQWFATGAGDRVIKIWDLASGELKLSLTGHISTIRGL 230 Query: 543 RFTPDGRWIVSGGADSSVK 599 + ++ S D VK Sbjct: 231 AVSDRHPYLFSCAEDKMVK 249
>WD51A_MOUSE (Q8JZX3) WD-repeat protein 51A| Length = 405 Score = 85.1 bits (209), Expect = 1e-16 Identities = 47/166 (28%), Positives = 78/166 (46%) Frame = +3 Query: 99 ATKRAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSP 278 +T R L H + V CAKF R +++ +D+ V LW + S Sbjct: 131 STHRQRFLFSLTQHINWVRCAKFSP-DGRLIVSASDDKTVKLWDKTSRECIHSYCEHGGF 189 Query: 279 VESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSS 458 V + F S I A T+K+WD ++++ + H + +L HP G++ + SS Sbjct: 190 VTYVDFHPSGTCIAAAGMDNTVKVWDARTHRLLQHYQLHSAAVNALSFHPSGNYLITASS 249 Query: 459 DTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 D+ +KI D+ + R ++T GH G + F+ G + SGG+D V Sbjct: 250 DSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQV 295 Score = 83.6 bits (205), Expect = 4e-16 Identities = 41/157 (26%), Positives = 77/157 (49%) Frame = +3 Query: 129 FVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSE 308 F AH + V F ++L+T +D+ V +W+ + + SL+ + V F Sbjct: 99 FRAHTATVRSVHFCS-DGQSLVTASDDKTVKVWSTHRQRFLFSLTQHINWVRCAKFSPDG 157 Query: 309 VMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMR 488 +I + + T+K+WD + + ++ H +D HP G A+ D +K+WD R Sbjct: 158 RLIVSASDDKTVKLWDKTSRECIHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDAR 217 Query: 489 KKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 R + YQ H+ ++ L F P G ++++ +DS++K Sbjct: 218 THRLLQHYQLHSAAVNALSFHPSGNYLITASSDSTLK 254 Score = 58.5 bits (140), Expect = 1e-08 Identities = 31/120 (25%), Positives = 53/120 (44%) Frame = +3 Query: 240 PTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLD 419 P+ G V + F + + +G+ T+ IW ++ FTGH+ ++ Sbjct: 9 PSLERHFKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKPQSRAYRFTGHKDAVTCVN 68 Query: 420 SHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 P G ASGS D ++IW K ++ HT + + F DG+ +V+ D +VK Sbjct: 69 FSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVK 128 Score = 51.2 bits (121), Expect = 2e-06 Identities = 24/80 (30%), Positives = 39/80 (48%) Frame = +3 Query: 360 EEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDV 539 E+ + R F GHR +D ASGS D+ + IW M+ + + + GH + Sbjct: 7 EDPSLERHFKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKPQSRAYRFTGHKDAVTC 66 Query: 540 LRFTPDGRWIVSGGADSSVK 599 + F+P G + SG D +V+ Sbjct: 67 VNFSPSGHLLASGSRDKTVR 86 Score = 49.7 bits (117), Expect = 6e-06 Identities = 29/120 (24%), Positives = 53/120 (44%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 + + H VT F + + G D V +W + ++ V +LSF Sbjct: 180 IHSYCEHGGFVTYVDFHP-SGTCIAAAGMDNTVKVWDARTHRLLQHYQLHSAAVNALSFH 238 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 S + ++ T+KI D+ E +++ T GH+ ++ G++FASG SD + +W Sbjct: 239 PSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVW 298
>TAF5L_MOUSE (Q91WQ5) TAF5-like RNA polymerase II p300/CBP-associated| factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65-beta) Length = 589 Score = 84.7 bits (208), Expect = 2e-16 Identities = 40/135 (29%), Positives = 65/135 (48%) Frame = +3 Query: 195 TGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKV 374 +G D+ LW+ + + +G + V+ + F + + G+ T+++W ++ Sbjct: 401 SGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNS 460 Query: 375 VRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTP 554 VR FTGHR SL P G + AS D +K+WD+ +GHT I L F+P Sbjct: 461 VRLFTGHRGPVLSLSFSPNGKYLASAGEDQRLKLWDLASGTLFKELRGHTDSITSLAFSP 520 Query: 555 DGRWIVSGGADSSVK 599 D I S D+SV+ Sbjct: 521 DSGLIASASMDNSVR 535 Score = 82.8 bits (203), Expect = 7e-16 Identities = 43/142 (30%), Positives = 67/142 (47%) Frame = +3 Query: 108 RAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVES 287 R Y L+ + H +DV C KF S L TG D+ V LW+ + +V +G PV S Sbjct: 415 RTYPLRIYAGHLADVDCVKFHPN-SNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLS 473 Query: 288 LSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTN 467 LSF + + + +K+WD+ + + GH + SL P AS S D + Sbjct: 474 LSFSPNGKYLASAGEDQRLKLWDLASGTLFKELRGHTDSITSLAFSPDSGLIASASMDNS 533 Query: 468 MKIWDMRKKRCIHTYQGHTGRI 533 +++WD+R C G +G + Sbjct: 534 VRVWDIRSTCCNTPADGSSGEL 555 Score = 79.3 bits (194), Expect = 8e-15 Identities = 34/140 (24%), Positives = 69/140 (49%) Frame = +3 Query: 180 SRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDI 359 S L++ ED + W +G T + G PV + + +G+ T ++W Sbjct: 354 SSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDVDISPFSLYFASGSHDRTARLWSF 413 Query: 360 EEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDV 539 + +R + GH ++ + HP ++ A+GS+D +++W ++ + + GH G + Sbjct: 414 DRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLS 473 Query: 540 LRFTPDGRWIVSGGADSSVK 599 L F+P+G+++ S G D +K Sbjct: 474 LSFSPNGKYLASAGEDQRLK 493 Score = 60.5 bits (145), Expect = 4e-09 Identities = 31/119 (26%), Positives = 55/119 (46%) Frame = +3 Query: 243 TAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDS 422 T + L G PV S F + + + + +I+ WD+ + GH +D Sbjct: 333 TEMKILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDVDI 392 Query: 423 HPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 PF +FASGS D ++W + + Y GH +D ++F P+ ++ +G D +V+ Sbjct: 393 SPFSLYFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVR 451
>WDR57_PONPY (Q5RF51) WD-repeat protein 57| Length = 357 Score = 84.7 bits (208), Expect = 2e-16 Identities = 49/168 (29%), Positives = 84/168 (50%), Gaps = 8/168 (4%) Frame = +3 Query: 117 KLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSF 296 +++ H S V +R + + TG +D V LW + K A+ + T V +++F Sbjct: 143 RVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAIQTFQN-TYQVLAVTF 201 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 + + I +G IK+WD+ + K+ T GH + L G + S + D +++ Sbjct: 202 NDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRV 261 Query: 477 WDMR----KKRCIHTYQG--HTGRIDVLR--FTPDGRWIVSGGADSSV 596 WD+R K+RC+ +QG H ++LR ++PDG I +G AD SV Sbjct: 262 WDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRSV 309 Score = 75.5 bits (184), Expect = 1e-13 Identities = 49/158 (31%), Positives = 78/158 (49%), Gaps = 4/158 (2%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAV-GKPTAVLSLSGLTSPVESLSFDSSEVM 314 H +V C KF S TL + G D+ + LW V G +L G + V L +++ M Sbjct: 65 HEGEVYCCKFHPNGS-TLASAGFDRLILLWNVYGDCGNYATLKGYSGAVMELHYNTDGSM 123 Query: 315 IGAGAASGTIKIWDIEEAKVVRTFTGHRS---NCASLDSHPFGDFFASGSSDTNMKIWDM 485 + + + T+ +WD E + V+ GH S +C P +GS D +K+WD+ Sbjct: 124 LFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGP--QLVCTGSDDGTVKLWDI 181 Query: 486 RKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 RKK I T+Q +T ++ + F I+SGG D+ +K Sbjct: 182 RKKAAIQTFQ-NTYQVLAVTFNDTSDQIISGGIDNDIK 218 Score = 70.9 bits (172), Expect = 3e-12 Identities = 39/145 (26%), Positives = 69/145 (47%), Gaps = 8/145 (5%) Frame = +3 Query: 177 TSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWD 356 TS +I+GG D + +W + + ++ G V LS S + + A T+++WD Sbjct: 204 TSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWD 263 Query: 357 IE----EAKVVRTFTGH----RSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTY 512 + + + V+ F G+ N P G A+GS+D ++ +WD +R ++ Sbjct: 264 VRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRSVCVWDTTSRRILYKL 323 Query: 513 QGHTGRIDVLRFTPDGRWIVSGGAD 587 GH G I+ + F PD I+S +D Sbjct: 324 PGHAGSINEVAFHPDEPIIISASSD 348 Score = 64.7 bits (156), Expect = 2e-10 Identities = 36/138 (26%), Positives = 68/138 (49%), Gaps = 1/138 (0%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESL-SFDSSEVMIGAGAASGTIKIWDIEE 365 L + D+ V +W V L G TS V S ++ G+ GT+K+WDI + Sbjct: 124 LFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRK 183 Query: 366 AKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLR 545 ++TF + ++ + D SG D ++K+WD+R+ + +T +GH + L Sbjct: 184 KAAIQTFQ-NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLS 242 Query: 546 FTPDGRWIVSGGADSSVK 599 + +G +++S D++V+ Sbjct: 243 LSSEGSYLLSNAMDNTVR 260 Score = 35.0 bits (79), Expect = 0.17 Identities = 29/125 (23%), Positives = 47/125 (37%), Gaps = 8/125 (6%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVG----KPTAVLSLSGLTSPVES----LS 293 HA VT S L++ D V +W V K V G E S Sbjct: 234 HADSVTGLSLSSEGSY-LLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCS 292 Query: 294 FDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMK 473 + I AG+A ++ +WD +++ GH + + HP S SSD + Sbjct: 293 WSPDGSKIAAGSADRSVCVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSDKRLY 352 Query: 474 IWDMR 488 + +++ Sbjct: 353 MGEIQ 357 Score = 32.0 bits (71), Expect = 1.4 Identities = 19/76 (25%), Positives = 32/76 (42%), Gaps = 2/76 (2%) Frame = +3 Query: 375 VRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRC--IHTYQGHTGRIDVLRF 548 + +GH HP G AS D + +W++ C T +G++G + L + Sbjct: 59 IMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGD-CGNYATLKGYSGAVMELHY 117 Query: 549 TPDGRWIVSGGADSSV 596 DG + S D +V Sbjct: 118 NTDGSMLFSASTDKTV 133
>TAF5L_HUMAN (O75529) TAF5-like RNA polymerase II p300/CBP-associated| factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65-beta) Length = 589 Score = 84.0 bits (206), Expect = 3e-16 Identities = 40/135 (29%), Positives = 65/135 (48%) Frame = +3 Query: 195 TGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKV 374 +G D+ LW+ + + +G + V+ + F + + G+ T+++W ++ Sbjct: 401 SGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNS 460 Query: 375 VRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTP 554 VR FTGHR SL P G + AS D +K+WD+ +GHT I L F+P Sbjct: 461 VRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSP 520 Query: 555 DGRWIVSGGADSSVK 599 D I S D+SV+ Sbjct: 521 DSGLIASASMDNSVR 535 Score = 82.4 bits (202), Expect = 9e-16 Identities = 42/142 (29%), Positives = 66/142 (46%) Frame = +3 Query: 108 RAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVES 287 R Y L+ + H +DV C KF S L TG D+ V LW+ + +V +G PV S Sbjct: 415 RTYPLRIYAGHLADVDCVKFHPN-SNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLS 473 Query: 288 LSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTN 467 L+F + + + +K+WD+ + + GH N SL P AS S D + Sbjct: 474 LAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSGLIASASMDNS 533 Query: 468 MKIWDMRKKRCIHTYQGHTGRI 533 +++WD+R C G + + Sbjct: 534 VRVWDIRNTYCSAPADGSSSEL 555 Score = 80.5 bits (197), Expect = 3e-15 Identities = 35/140 (25%), Positives = 69/140 (49%) Frame = +3 Query: 180 SRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDI 359 S L++ ED + W +G T + G PV L + +G+ T ++W Sbjct: 354 SSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYSLYFASGSHDRTARLWSF 413 Query: 360 EEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDV 539 + +R + GH ++ + HP ++ A+GS+D +++W ++ + + GH G + Sbjct: 414 DRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLS 473 Query: 540 LRFTPDGRWIVSGGADSSVK 599 L F+P+G+++ S G D +K Sbjct: 474 LAFSPNGKYLASAGEDQRLK 493 Score = 60.5 bits (145), Expect = 4e-09 Identities = 31/119 (26%), Positives = 55/119 (46%) Frame = +3 Query: 243 TAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDS 422 T + L G PV S F + + + + +I+ WD+ + GH LD Sbjct: 333 TEMKILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDI 392 Query: 423 HPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 P+ +FASGS D ++W + + Y GH +D ++F P+ ++ +G D +V+ Sbjct: 393 SPYSLYFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVR 451
>PLRG1_RAT (Q9WUC8) Pleiotropic regulator 1| Length = 514 Score = 83.6 bits (205), Expect = 4e-16 Identities = 41/136 (30%), Positives = 68/136 (50%) Frame = +3 Query: 192 ITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAK 371 +TG D+ + +W + LSL+G S V + + + + +K WD+E K Sbjct: 220 VTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNK 279 Query: 372 VVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFT 551 V+R + GH S LD HP D + S D+ +IWD+R K +HT GHT + +R Sbjct: 280 VIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQ 339 Query: 552 PDGRWIVSGGADSSVK 599 I++G D++++ Sbjct: 340 AAEPQIITGSHDTTIR 355 Score = 70.9 bits (172), Expect = 3e-12 Identities = 44/138 (31%), Positives = 66/138 (47%) Frame = +3 Query: 177 TSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWD 356 T L+T D +W V +V +LSG T+ V ++ ++E I G+ TI++WD Sbjct: 299 TIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWD 358 Query: 357 IEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRID 536 + K T T H+ + ++ HP FASGS D N+K W I GH I+ Sbjct: 359 LVAGKTRVTLTNHKKSVRAVVLHPLHYTFASGSPD-NIKQWKFPDGGFIQNLSGHNAIIN 417 Query: 537 VLRFTPDGRWIVSGGADS 590 L DG ++ GAD+ Sbjct: 418 TLAVNTDG--VLVSGADN 433 Score = 49.3 bits (116), Expect = 8e-06 Identities = 31/134 (23%), Positives = 55/134 (41%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L + GED++V W + + G S V L + ++ + T +IWD+ Sbjct: 261 LFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTK 320 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 V T +GH + A++ +GS DT +++WD+ + T H + + Sbjct: 321 ASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVL 380 Query: 549 TPDGRWIVSGGADS 590 P SG D+ Sbjct: 381 HPLHYTFASGSPDN 394 Score = 38.9 bits (89), Expect = 0.011 Identities = 20/77 (25%), Positives = 35/77 (45%) Frame = +3 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 K+ R +GH + P +F +GS+D +KIWD+ + + GH + + Sbjct: 195 KLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIV 254 Query: 549 TPDGRWIVSGGADSSVK 599 + ++ S G D VK Sbjct: 255 STRSPYLFSCGEDKQVK 271 Score = 29.3 bits (64), Expect = 9.1 Identities = 19/87 (21%), Positives = 39/87 (44%), Gaps = 7/87 (8%) Frame = +3 Query: 117 KLQEFVAHASDVTCAKFGKRTSRTLI-------TGGEDQKVNLWAVGKPTAVLSLSGLTS 275 +L + VA + VT K ++ G + W + +LSG + Sbjct: 355 RLWDLVAGKTRVTLTNHKKSVRAVVLHPLHYTFASGSPDNIKQWKFPDGGFIQNLSGHNA 414 Query: 276 PVESLSFDSSEVMIGAGAASGTIKIWD 356 + +L+ ++ V++ +GA +GT+ +WD Sbjct: 415 IINTLAVNTDGVLV-SGADNGTMHLWD 440
>PLRG1_HUMAN (O43660) Pleiotropic regulator 1| Length = 514 Score = 83.6 bits (205), Expect = 4e-16 Identities = 41/136 (30%), Positives = 68/136 (50%) Frame = +3 Query: 192 ITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAK 371 +TG D+ + +W + LSL+G S V + + + + +K WD+E K Sbjct: 220 VTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNK 279 Query: 372 VVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFT 551 V+R + GH S LD HP D + S D+ +IWD+R K +HT GHT + +R Sbjct: 280 VIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQ 339 Query: 552 PDGRWIVSGGADSSVK 599 I++G D++++ Sbjct: 340 AAEPQIITGSHDTTIR 355 Score = 70.1 bits (170), Expect = 5e-12 Identities = 44/138 (31%), Positives = 66/138 (47%) Frame = +3 Query: 177 TSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWD 356 T L+T D +W V +V +LSG T+ V ++ ++E I G+ TI++WD Sbjct: 299 TIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWD 358 Query: 357 IEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRID 536 + K T T H+ + ++ HP FASGS D N+K W I GH I+ Sbjct: 359 LVAGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPD-NIKQWKFPDGSFIQNLSGHNAIIN 417 Query: 537 VLRFTPDGRWIVSGGADS 590 L DG ++ GAD+ Sbjct: 418 TLTVNSDG--VLVSGADN 433 Score = 50.1 bits (118), Expect = 5e-06 Identities = 31/134 (23%), Positives = 55/134 (41%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L + GED++V W + + G S V L + ++ + T +IWD+ Sbjct: 261 LFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTK 320 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 V T +GH + A++ +GS DT +++WD+ + T H + + Sbjct: 321 ASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVL 380 Query: 549 TPDGRWIVSGGADS 590 P SG D+ Sbjct: 381 HPRHYTFASGSPDN 394 Score = 38.9 bits (89), Expect = 0.011 Identities = 20/77 (25%), Positives = 35/77 (45%) Frame = +3 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 K+ R +GH + P +F +GS+D +KIWD+ + + GH + + Sbjct: 195 KLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIV 254 Query: 549 TPDGRWIVSGGADSSVK 599 + ++ S G D VK Sbjct: 255 STRSPYLFSCGEDKQVK 271 Score = 31.6 bits (70), Expect = 1.8 Identities = 20/87 (22%), Positives = 40/87 (45%), Gaps = 7/87 (8%) Frame = +3 Query: 117 KLQEFVAHASDVTCAKFGKRTSRTLI-------TGGEDQKVNLWAVGKPTAVLSLSGLTS 275 +L + VA + VT K ++ G + W + + +LSG + Sbjct: 355 RLWDLVAGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQWKFPDGSFIQNLSGHNA 414 Query: 276 PVESLSFDSSEVMIGAGAASGTIKIWD 356 + +L+ +S V++ +GA +GT+ +WD Sbjct: 415 IINTLTVNSDGVLV-SGADNGTMHLWD 440
>PLRG1_MOUSE (Q922V4) Pleiotropic regulator 1| Length = 513 Score = 83.6 bits (205), Expect = 4e-16 Identities = 41/136 (30%), Positives = 68/136 (50%) Frame = +3 Query: 192 ITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAK 371 +TG D+ + +W + LSL+G S V + + + + +K WD+E K Sbjct: 219 VTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNK 278 Query: 372 VVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFT 551 V+R + GH S LD HP D + S D+ +IWD+R K +HT GHT + +R Sbjct: 279 VIRHYHGHLSAVYGLDLHPTLDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQ 338 Query: 552 PDGRWIVSGGADSSVK 599 I++G D++++ Sbjct: 339 AAEPQIITGSHDTTIR 354 Score = 70.1 bits (170), Expect = 5e-12 Identities = 44/138 (31%), Positives = 66/138 (47%) Frame = +3 Query: 177 TSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWD 356 T L+T D +W V +V +LSG T+ V ++ ++E I G+ TI++WD Sbjct: 298 TLDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWD 357 Query: 357 IEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRID 536 + K T T H+ + ++ HP FASGS D N+K W I GH I+ Sbjct: 358 LVAGKTRVTLTNHKKSVRAVVLHPLLYTFASGSPD-NIKQWKFPDGGFIQNLSGHNAIIN 416 Query: 537 VLRFTPDGRWIVSGGADS 590 L DG ++ GAD+ Sbjct: 417 TLAVNADG--VLVSGADN 432 Score = 48.5 bits (114), Expect = 1e-05 Identities = 31/134 (23%), Positives = 55/134 (41%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L + GED++V W + + G S V L + ++ + T +IWD+ Sbjct: 260 LFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTLDVLVTCSRDSTARIWDVRTK 319 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 V T +GH + A++ +GS DT +++WD+ + T H + + Sbjct: 320 ASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVL 379 Query: 549 TPDGRWIVSGGADS 590 P SG D+ Sbjct: 380 HPLLYTFASGSPDN 393 Score = 38.9 bits (89), Expect = 0.011 Identities = 20/77 (25%), Positives = 35/77 (45%) Frame = +3 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 K+ R +GH + P +F +GS+D +KIWD+ + + GH + + Sbjct: 194 KLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIV 253 Query: 549 TPDGRWIVSGGADSSVK 599 + ++ S G D VK Sbjct: 254 STRSPYLFSCGEDKQVK 270 Score = 29.3 bits (64), Expect = 9.1 Identities = 19/87 (21%), Positives = 39/87 (44%), Gaps = 7/87 (8%) Frame = +3 Query: 117 KLQEFVAHASDVTCAKFGKRTSRTLI-------TGGEDQKVNLWAVGKPTAVLSLSGLTS 275 +L + VA + VT K ++ G + W + +LSG + Sbjct: 354 RLWDLVAGKTRVTLTNHKKSVRAVVLHPLLYTFASGSPDNIKQWKFPDGGFIQNLSGHNA 413 Query: 276 PVESLSFDSSEVMIGAGAASGTIKIWD 356 + +L+ ++ V++ +GA +GT+ +WD Sbjct: 414 IINTLAVNADGVLV-SGADNGTMHLWD 439
>FBXW7_MOUSE (Q8VBV4) F-box/WD-repeat protein 7 (F-box and WD-40 domain protein| 7) (F-box protein FBW7) (F-box protein Fbxw6) (F-box-WD40 repeat protein 6) (SEL-10) Length = 629 Score = 83.6 bits (205), Expect = 4e-16 Identities = 50/179 (27%), Positives = 93/179 (51%), Gaps = 9/179 (5%) Frame = +3 Query: 90 SRMATKRAYKLQE------FVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAV 251 SR AT R + ++ + H + V C ++ R +++G D V +W T + Sbjct: 400 SRDATLRVWDIETGQCLHVLMGHVAAVRCVQYD---GRRVVSGAYDFMVKVWDPETETCL 456 Query: 252 LSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPF 431 +L G T+ V SL FD V+ +G+ +I++WD+E + T TGH+S + ++ Sbjct: 457 HTLQGHTNRVYSLQFDGIHVV--SGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKD- 513 Query: 432 GDFFASGSSDTNMKIWDMRKKRCIHTYQG---HTGRIDVLRFTPDGRWIVSGGADSSVK 599 + SG++D+ +KIWD++ +C+ T QG H + L+F + ++++ D +VK Sbjct: 514 -NILVSGNADSTVKIWDIKTGQCLQTLQGPSKHQSAVTCLQFNKN--FVITSSDDGTVK 569 Score = 80.5 bits (197), Expect = 3e-15 Identities = 48/162 (29%), Positives = 79/162 (48%), Gaps = 2/162 (1%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 L+ V H V ++ +I+G D+ + +W + +L G TS V + Sbjct: 336 LRTLVGHTGGVWSSQM---RDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLH 392 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRS--NCASLDSHPFGDFFASGSSDTNMK 473 V+ +G+ T+++WDIE + + GH + C D G SG+ D +K Sbjct: 393 EKRVV--SGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYD----GRRVVSGAYDFMVK 446 Query: 474 IWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 +WD + C+HT QGHT R+ L+F DG +VSG D+S++ Sbjct: 447 VWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIR 486 Score = 72.8 bits (177), Expect = 7e-13 Identities = 45/154 (29%), Positives = 72/154 (46%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMI 317 H S V C ++ +++G D + +W + + L G + V + +D V+ Sbjct: 382 HTSTVRCMHLHEKR---VVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVV- 437 Query: 318 GAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKR 497 +GA +K+WD E + T GH + SL G SGS DT++++WD+ Sbjct: 438 -SGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFD--GIHVVSGSLDTSIRVWDVETGN 494 Query: 498 CIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 CIHT GH + + +VSG ADS+VK Sbjct: 495 CIHTLTGHQSLTSGMELKDN--ILVSGNADSTVK 526 Score = 56.2 bits (134), Expect = 7e-08 Identities = 29/95 (30%), Positives = 47/95 (49%) Frame = +3 Query: 315 IGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKK 494 I +G+ T+K+W K +RT GH S S + SGS+D +K+W+ Sbjct: 316 IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWS--SQMRDNIIISGSTDRTLKVWNAETG 373 Query: 495 RCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 CIHT GHT + + + +VSG D++++ Sbjct: 374 ECIHTLYGHTSTVRCMHL--HEKRVVSGSRDATLR 406 Score = 38.9 bits (89), Expect = 0.011 Identities = 22/82 (26%), Positives = 38/82 (46%) Frame = +3 Query: 354 DIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRI 533 +++ KV++ H C G+ SGS D +K+W +C+ T GHTG + Sbjct: 291 ELKSPKVLKGHDDHVITCLQF----CGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGV 346 Query: 534 DVLRFTPDGRWIVSGGADSSVK 599 + + I+SG D ++K Sbjct: 347 WSSQMRDN--IIISGSTDRTLK 366 Score = 34.3 bits (77), Expect = 0.28 Identities = 18/67 (26%), Positives = 35/67 (52%), Gaps = 3/67 (4%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLT---SPVESLSFDSSEVMIGAGAASGTIKIWDI 359 L++G D V +W + + +L G + S V L F+ + V+ + GT+K+WD+ Sbjct: 516 LVSGNADSTVKIWDIKTGQCLQTLQGPSKHQSAVTCLQFNKNFVITSSD--DGTVKLWDL 573 Query: 360 EEAKVVR 380 + + +R Sbjct: 574 KTGEFIR 580
>FBXW7_HUMAN (Q969H0) F-box/WD-repeat protein 7 (F-box and WD-40 domain protein| 7) (F-box protein FBX30) (hCdc4) (Archipelago homolog) (hAgo) (SEL-10) Length = 707 Score = 83.6 bits (205), Expect = 4e-16 Identities = 50/179 (27%), Positives = 93/179 (51%), Gaps = 9/179 (5%) Frame = +3 Query: 90 SRMATKRAYKLQE------FVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAV 251 SR AT R + ++ + H + V C ++ R +++G D V +W T + Sbjct: 478 SRDATLRVWDIETGQCLHVLMGHVAAVRCVQYD---GRRVVSGAYDFMVKVWDPETETCL 534 Query: 252 LSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPF 431 +L G T+ V SL FD V+ +G+ +I++WD+E + T TGH+S + ++ Sbjct: 535 HTLQGHTNRVYSLQFDGIHVV--SGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKD- 591 Query: 432 GDFFASGSSDTNMKIWDMRKKRCIHTYQG---HTGRIDVLRFTPDGRWIVSGGADSSVK 599 + SG++D+ +KIWD++ +C+ T QG H + L+F + ++++ D +VK Sbjct: 592 -NILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKN--FVITSSDDGTVK 647 Score = 80.5 bits (197), Expect = 3e-15 Identities = 48/162 (29%), Positives = 79/162 (48%), Gaps = 2/162 (1%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 L+ V H V ++ +I+G D+ + +W + +L G TS V + Sbjct: 414 LRTLVGHTGGVWSSQM---RDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLH 470 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRS--NCASLDSHPFGDFFASGSSDTNMK 473 V+ +G+ T+++WDIE + + GH + C D G SG+ D +K Sbjct: 471 EKRVV--SGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYD----GRRVVSGAYDFMVK 524 Query: 474 IWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 +WD + C+HT QGHT R+ L+F DG +VSG D+S++ Sbjct: 525 VWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIR 564 Score = 72.8 bits (177), Expect = 7e-13 Identities = 45/154 (29%), Positives = 72/154 (46%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMI 317 H S V C ++ +++G D + +W + + L G + V + +D V+ Sbjct: 460 HTSTVRCMHLHEKR---VVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVV- 515 Query: 318 GAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKR 497 +GA +K+WD E + T GH + SL G SGS DT++++WD+ Sbjct: 516 -SGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFD--GIHVVSGSLDTSIRVWDVETGN 572 Query: 498 CIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 CIHT GH + + +VSG ADS+VK Sbjct: 573 CIHTLTGHQSLTSGMELKDN--ILVSGNADSTVK 604 Score = 56.2 bits (134), Expect = 7e-08 Identities = 29/95 (30%), Positives = 47/95 (49%) Frame = +3 Query: 315 IGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKK 494 I +G+ T+K+W K +RT GH S S + SGS+D +K+W+ Sbjct: 394 IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWS--SQMRDNIIISGSTDRTLKVWNAETG 451 Query: 495 RCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 CIHT GHT + + + +VSG D++++ Sbjct: 452 ECIHTLYGHTSTVRCMHL--HEKRVVSGSRDATLR 484 Score = 38.9 bits (89), Expect = 0.011 Identities = 22/82 (26%), Positives = 38/82 (46%) Frame = +3 Query: 354 DIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRI 533 +++ KV++ H C G+ SGS D +K+W +C+ T GHTG + Sbjct: 369 ELKSPKVLKGHDDHVITCLQF----CGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGV 424 Query: 534 DVLRFTPDGRWIVSGGADSSVK 599 + + I+SG D ++K Sbjct: 425 WSSQMRDN--IIISGSTDRTLK 444 Score = 33.9 bits (76), Expect = 0.37 Identities = 18/67 (26%), Positives = 34/67 (50%), Gaps = 3/67 (4%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLT---SPVESLSFDSSEVMIGAGAASGTIKIWDI 359 L++G D V +W + + +L G S V L F+ + V+ + GT+K+WD+ Sbjct: 594 LVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSD--DGTVKLWDL 651 Query: 360 EEAKVVR 380 + + +R Sbjct: 652 KTGEFIR 658
>WDR57_MOUSE (Q6PE01) WD-repeat protein 57| Length = 358 Score = 82.8 bits (203), Expect = 7e-16 Identities = 49/168 (29%), Positives = 83/168 (49%), Gaps = 8/168 (4%) Frame = +3 Query: 117 KLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSF 296 +++ H S V +R + + TG +D V LW + K AV + T V +++F Sbjct: 144 RVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAVQTFQN-TYQVLAVTF 202 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 + + I +G IK+WD+ + K+ T GH + L G + S + D +++ Sbjct: 203 NDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRV 262 Query: 477 WDMR----KKRCIHTYQG--HTGRIDVLR--FTPDGRWIVSGGADSSV 596 WD+R K+RC+ +QG H ++LR ++PDG I +G AD V Sbjct: 263 WDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFV 310 Score = 68.9 bits (167), Expect = 1e-11 Identities = 39/145 (26%), Positives = 68/145 (46%), Gaps = 8/145 (5%) Frame = +3 Query: 177 TSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWD 356 TS +I+GG D + +W + + ++ G V LS S + + A T+++WD Sbjct: 205 TSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWD 264 Query: 357 IE----EAKVVRTFTGH----RSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTY 512 + + + V+ F G+ N P G A+GS+D + +WD +R ++ Sbjct: 265 VRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRVLYKL 324 Query: 513 QGHTGRIDVLRFTPDGRWIVSGGAD 587 GH G I+ + F PD I+S +D Sbjct: 325 PGHAGSINEVAFHPDEPIILSASSD 349 Score = 65.1 bits (157), Expect = 1e-10 Identities = 37/138 (26%), Positives = 68/138 (49%), Gaps = 1/138 (0%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESL-SFDSSEVMIGAGAASGTIKIWDIEE 365 L + D+ V +W V L G TS V S ++ G+ GT+K+WDI + Sbjct: 125 LFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRK 184 Query: 366 AKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLR 545 V+TF + ++ + D SG D ++K+WD+R+ + +T +GH + L Sbjct: 185 KAAVQTFQ-NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLS 243 Query: 546 FTPDGRWIVSGGADSSVK 599 + +G +++S D++V+ Sbjct: 244 LSSEGSYLLSNAMDNTVR 261 Score = 35.0 bits (79), Expect = 0.17 Identities = 24/114 (21%), Positives = 43/114 (37%), Gaps = 1/114 (0%) Frame = +3 Query: 249 VLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIE-EAKVVRTFTGHRSNCASLDSH 425 ++ LSG V F + + + I +W++ + T GH L + Sbjct: 60 IMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYN 119 Query: 426 PFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGAD 587 G S S+D + +WD + +GHT ++ G +V G+D Sbjct: 120 TDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSD 173 Score = 34.7 bits (78), Expect = 0.22 Identities = 30/125 (24%), Positives = 46/125 (36%), Gaps = 8/125 (6%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVG----KPTAVLSLSGLTSPVES----LS 293 HA VT S L++ D V +W V K V G E S Sbjct: 235 HADSVTGLSLSSEGSY-LLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCS 293 Query: 294 FDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMK 473 + I AG+A + +WD +V+ GH + + HP S SSD + Sbjct: 294 WSPDGSKIAAGSADRFVYVWDTTSRRVLYKLPGHAGSINEVAFHPDEPIILSASSDKRLY 353 Query: 474 IWDMR 488 + +++ Sbjct: 354 MGEIQ 358
>PRP46_YEAST (Q12417) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) (Complexed with CEF1 protein 1) (PRP19-associated complex protein 50) (PRP nineteen-associated complex protein 50) Length = 451 Score = 82.8 bits (203), Expect = 7e-16 Identities = 46/174 (26%), Positives = 81/174 (46%), Gaps = 1/174 (0%) Frame = +3 Query: 81 LLPSRMATKRAYKLQEFV-AHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLS 257 LL R +KL + H V C + ITG D + +W + + Sbjct: 118 LLSQRPEWHAPWKLSRVINGHLGWVRCVAIDPVDNEWFITGSNDTTMKVWDLATGKLKTT 177 Query: 258 LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGD 437 L+G V ++ + + + T+K WD+E+ +++R + GH S ++ HP D Sbjct: 178 LAGHVMTVRDVAVSDRHPYLFSVSEDKTVKCWDLEKNQIIRDYYGHLSGVRTVSIHPTLD 237 Query: 438 FFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 A+ D+ +K+WDMR + + T GH G I+ ++ TP +VS D++V+ Sbjct: 238 LIATAGRDSVIKLWDMRTRIPVITLVGHKGPINQVQCTPVDPQVVSSSTDATVR 291 Score = 53.5 bits (127), Expect = 4e-07 Identities = 31/160 (19%), Positives = 70/160 (43%), Gaps = 1/160 (0%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 ++++ H S V T + T G D + LW + V++L G P+ + Sbjct: 217 IRDYYGHLSGVRTVSIHP-TLDLIATAGRDSVIKLWDMRTRIPVITLVGHKGPINQVQCT 275 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 + + + + T+++WD+ K ++ T H+ + + HP +F + + +++ W Sbjct: 276 PVDPQVVSSSTDATVRLWDVVAGKTMKVLTHHKRSVRATALHP-KEFSVASACTDDIRSW 334 Query: 480 DMRKKRCIHTYQGH-TGRIDVLRFTPDGRWIVSGGADSSV 596 + + + ++ TG I+ L D ++ G D+ V Sbjct: 335 GLAEGSLLTNFESEKTGIINTLSINQDD--VLFAGGDNGV 372 Score = 47.0 bits (110), Expect = 4e-05 Identities = 25/99 (25%), Positives = 42/99 (42%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L + ED+ V W + K + G S V ++S + +I IK+WD+ Sbjct: 197 LFSVSEDKTVKCWDLEKNQIIRDYYGHLSGVRTVSIHPTLDLIATAGRDSVIKLWDMRTR 256 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDM 485 V T GH+ + P S S+D +++WD+ Sbjct: 257 IPVITLVGHKGPINQVQCTPVDPQVVSSSTDATVRLWDV 295
>WDR57_HUMAN (Q96DI7) WD-repeat protein 57 (Prp8-binding protein) (hPRP8BP) (U5| snRNP-specific 40 kDa protein) (38 kDa splicing factor) Length = 357 Score = 82.4 bits (202), Expect = 9e-16 Identities = 48/168 (28%), Positives = 83/168 (49%), Gaps = 8/168 (4%) Frame = +3 Query: 117 KLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSF 296 +++ H S V +R + + TG +D V LW + K A+ + T V +++F Sbjct: 143 RVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAIQTFQN-TYQVLAVTF 201 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 + + I +G IK+WD+ + K+ T GH + L G + S + D +++ Sbjct: 202 NDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRV 261 Query: 477 WDMR----KKRCIHTYQG--HTGRIDVLR--FTPDGRWIVSGGADSSV 596 WD+R K+RC+ +QG H ++LR ++PDG I +G AD V Sbjct: 262 WDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFV 309 Score = 69.7 bits (169), Expect = 6e-12 Identities = 39/145 (26%), Positives = 68/145 (46%), Gaps = 8/145 (5%) Frame = +3 Query: 177 TSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWD 356 TS +I+GG D + +W + + ++ G V LS S + + A T+++WD Sbjct: 204 TSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWD 263 Query: 357 IE----EAKVVRTFTGH----RSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTY 512 + + + V+ F G+ N P G A+GS+D + +WD +R ++ Sbjct: 264 VRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILYKL 323 Query: 513 QGHTGRIDVLRFTPDGRWIVSGGAD 587 GH G I+ + F PD I+S +D Sbjct: 324 PGHAGSINEVAFHPDEPIIISASSD 348 Score = 64.7 bits (156), Expect = 2e-10 Identities = 36/138 (26%), Positives = 68/138 (49%), Gaps = 1/138 (0%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESL-SFDSSEVMIGAGAASGTIKIWDIEE 365 L + D+ V +W V L G TS V S ++ G+ GT+K+WDI + Sbjct: 124 LFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRK 183 Query: 366 AKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLR 545 ++TF + ++ + D SG D ++K+WD+R+ + +T +GH + L Sbjct: 184 KAAIQTFQ-NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLS 242 Query: 546 FTPDGRWIVSGGADSSVK 599 + +G +++S D++V+ Sbjct: 243 LSSEGSYLLSNAMDNTVR 260 Score = 35.0 bits (79), Expect = 0.17 Identities = 24/114 (21%), Positives = 43/114 (37%), Gaps = 1/114 (0%) Frame = +3 Query: 249 VLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIE-EAKVVRTFTGHRSNCASLDSH 425 ++ LSG V F + + + I +W++ + T GH L + Sbjct: 59 IMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYN 118 Query: 426 PFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGAD 587 G S S+D + +WD + +GHT ++ G +V G+D Sbjct: 119 TDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSD 172 Score = 34.3 bits (77), Expect = 0.28 Identities = 29/125 (23%), Positives = 46/125 (36%), Gaps = 8/125 (6%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVG----KPTAVLSLSGLTSPVES----LS 293 HA VT S L++ D V +W V K V G E S Sbjct: 234 HADSVTGLSLSSEGSY-LLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCS 292 Query: 294 FDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMK 473 + I AG+A + +WD +++ GH + + HP S SSD + Sbjct: 293 WSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSDKRLY 352 Query: 474 IWDMR 488 + +++ Sbjct: 353 MGEIQ 357
>UTP13_SCHPO (Q9USN3) Probable U3 small nucleolar RNA-associated protein 13 (U3| snoRNA-associated protein 13) Length = 777 Score = 80.9 bits (198), Expect = 3e-15 Identities = 39/142 (27%), Positives = 74/142 (52%), Gaps = 2/142 (1%) Frame = +3 Query: 180 SRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDI 359 S+ LI + + ++ + + S+ +PV +++ D + ++ G A G +K+WDI Sbjct: 73 SKKLIAAFRSRLLTIYEIPSGRRIKSMKAHETPVITMTIDPTNTLLATGGAEGLVKVWDI 132 Query: 360 EEAKVVRTFTGHRSNCASL--DSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRI 533 A V +F GH ++L H ASG+ D+ +++WD+ R + ++GH+ I Sbjct: 133 AGAYVTHSFRGHGGVISALCFGKHQNTWVLASGADDSRVRLWDLNSSRSMAVFEGHSSVI 192 Query: 534 DVLRFTPDGRWIVSGGADSSVK 599 L F P G +++SG D +V+ Sbjct: 193 RGLTFEPTGSFLLSGSRDKTVQ 214 Score = 74.7 bits (182), Expect = 2e-13 Identities = 46/169 (27%), Positives = 74/169 (43%), Gaps = 12/169 (7%) Frame = +3 Query: 129 FVAHASDVTCAKFGKRTSRT----LITGGEDQKVNLWAVGKPT--------AVLSLSGLT 272 F H + VT G L + +D+ + + +G AV ++ Sbjct: 406 FTGHTASVTAVALGPLDVNGYPTFLASSSQDRTLKRFNLGSQLNKSDFSNRAVWTIKAHD 465 Query: 273 SPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASG 452 V ++ +I + + TIK+WD +VV GHR + +PF ASG Sbjct: 466 RDVNAIQVSKDGRIIASASQDKTIKLWDSSTGEVVGVLRGHRRGVWACSFNPFSRQLASG 525 Query: 453 SSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 S D ++IW++ ++C+ T +GHTG I L + G +VS AD VK Sbjct: 526 SGDRTIRIWNVDTQQCVQTLEGHTGAILKLIYISQGTQVVSAAADGLVK 574 Score = 73.6 bits (179), Expect = 4e-13 Identities = 44/154 (28%), Positives = 70/154 (45%) Frame = +3 Query: 135 AHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVM 314 AH DV + K R + + +D+ + LW V L G V + SF+ Sbjct: 463 AHDRDVNAIQVSK-DGRIIASASQDKTIKLWDSSTGEVVGVLRGHRRGVWACSFNPFSRQ 521 Query: 315 IGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKK 494 + +G+ TI+IW+++ + V+T GH L G S ++D +K+W + Sbjct: 522 LASGSGDRTIRIWNVDTQQCVQTLEGHTGAILKLIYISQGTQVVSAAADGLVKVWSLSSG 581 Query: 495 RCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 C+ T H R+ L DG +VSGGAD+ V Sbjct: 582 ECVATLDNHEDRVWALASRFDGSLLVSGGADAVV 615 Score = 63.5 bits (153), Expect = 4e-10 Identities = 30/113 (26%), Positives = 55/113 (48%), Gaps = 2/113 (1%) Frame = +3 Query: 177 TSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEV--MIGAGAASGTIKI 350 T+ L TGG + V +W + S G + +L F + ++ +GA +++ Sbjct: 114 TNTLLATGGAEGLVKVWDIAGAYVTHSFRGHGGVISALCFGKHQNTWVLASGADDSRVRL 173 Query: 351 WDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHT 509 WD+ ++ + F GH S L P G F SGS D +++W+++K+ + T Sbjct: 174 WDLNSSRSMAVFEGHSSVIRGLTFEPTGSFLLSGSRDKTVQVWNIKKRSAVRT 226 Score = 50.8 bits (120), Expect = 3e-06 Identities = 26/106 (24%), Positives = 51/106 (48%), Gaps = 1/106 (0%) Frame = +3 Query: 279 VESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSS 458 V +L+ S + A S + I++I + +++ H + ++ P A+G + Sbjct: 64 VTALAITSDSKKLIAAFRSRLLTIYEIPSGRRIKSMKAHETPVITMTIDPTNTLLATGGA 123 Query: 459 DTNMKIWDMRKKRCIHTYQGHTGRIDVLRF-TPDGRWIVSGGADSS 593 + +K+WD+ H+++GH G I L F W+++ GAD S Sbjct: 124 EGLVKVWDIAGAYVTHSFRGHGGVISALCFGKHQNTWVLASGADDS 169 Score = 41.2 bits (95), Expect = 0.002 Identities = 19/75 (25%), Positives = 36/75 (48%), Gaps = 4/75 (5%) Frame = +3 Query: 342 IKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKK----RCIHT 509 I + + +V GH +LDS G + A+G+ D +++W++ + +CIH Sbjct: 346 IDVISTDGTQVFGVLEGHTDIVLTLDSSEDGVWLATGAKDNTVRLWNLNIEDNVYKCIHV 405 Query: 510 YQGHTGRIDVLRFTP 554 + GHT + + P Sbjct: 406 FTGHTASVTAVALGP 420
>PRP46_ASHGO (Q75BY3) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 425 Score = 80.9 bits (198), Expect = 3e-15 Identities = 44/154 (28%), Positives = 69/154 (44%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMI 317 H V C + TG D + +W + ++L G V + + + Sbjct: 112 HTGWVRCVCVDPVDNAWFATGSNDSTIRVWDLATGKLKVTLQGHIMTVRDICISARHPYM 171 Query: 318 GAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKR 497 + + +K WD+E VVR F G S S+D HP D S D+ +++WD+R + Sbjct: 172 FSASQDKLVKCWDLERNTVVRDFHGTLSGVHSVDLHPSLDLIVSAGRDSVVRVWDIRSRS 231 Query: 498 CIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 C+ T GH G I+ +R P IVS D++VK Sbjct: 232 CVLTLAGHRGPINKVRCLPVDPQIVSCSTDATVK 265 Score = 57.4 bits (137), Expect = 3e-08 Identities = 31/122 (25%), Positives = 51/122 (41%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 + + +D+ V W + + T V G S V S+ S +I + +++WDI Sbjct: 171 MFSASQDKLVKCWDLERNTVVRDFHGTLSGVHSVDLHPSLDLIVSAGRDSVVRVWDIRSR 230 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 V T GHR + P S S+D +K+WD+ + + T H + L F Sbjct: 231 SCVLTLAGHRGPINKVRCLPVDPQIVSCSTDATVKLWDLVAGKPMKTLTHHKRNVRDLAF 290 Query: 549 TP 554 P Sbjct: 291 NP 292 Score = 55.5 bits (132), Expect = 1e-07 Identities = 32/135 (23%), Positives = 65/135 (48%), Gaps = 1/135 (0%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 +++ G D V +W + + VL+L+G P+ + + I + + T+K+WD+ Sbjct: 213 IVSAGRDSVVRVWDIRSRSCVLTLAGHRGPINKVRCLPVDPQIVSCSTDATVKLWDLVAG 272 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHT-GRIDVLR 545 K ++T T H+ N L +P FAS +D +++ W + + + + G ++ L Sbjct: 273 KPMKTLTHHKRNVRDLAFNPTEFSFASACTD-DIRSWKLVDGQLLTNFNSEALGIVNTLA 331 Query: 546 FTPDGRWIVSGGADS 590 DG ++ G D+ Sbjct: 332 CNQDG--VLFAGGDT 344
>SPG16_MOUSE (Q8K450) Sperm-associated antigen 16 protein (PF20 protein homolog)| Length = 639 Score = 79.7 bits (195), Expect = 6e-15 Identities = 50/167 (29%), Positives = 76/167 (45%), Gaps = 1/167 (0%) Frame = +3 Query: 99 ATKRAYKLQE-FVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTS 275 A K YKL F H V+C LI+ ED+ + + + +L+ SG T Sbjct: 345 AAKFDYKLNNIFRLHELPVSCIVMHPCRDY-LISCSEDRLWKMVGLPQGNVLLTGSGHTD 403 Query: 276 PVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGS 455 + F S + + TIK+WD+ + + T GH S H GDF AS S Sbjct: 404 WLSGCCFHPSGSKLATSSGDSTIKLWDLNKGECTLTLEGHNHAVWSCTWHSCGDFVASAS 463 Query: 456 SDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 D KIWD+ +RC +T GHT ++ + F P +++ AD ++ Sbjct: 464 LDMTSKIWDVNSERCRYTLYGHTDSVNSIEFFPFSNILLTASADKTL 510 Score = 74.3 bits (181), Expect = 2e-13 Identities = 39/137 (28%), Positives = 61/137 (44%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L T D + LW + K L+L G V S ++ S + + + T KIWD+ Sbjct: 417 LATSSGDSTIKLWDLNKGECTLTLEGHNHAVWSCTWHSCGDFVASASLDMTSKIWDVNSE 476 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 + T GH + S++ PF + + S+D + +WD R +C + GH ++ F Sbjct: 477 RCRYTLYGHTDSVNSIEFFPFSNILLTASADKTLSVWDARTGKCEQSLYGHMHSVNDATF 536 Query: 549 TPDGRWIVSGGADSSVK 599 TP G I S A K Sbjct: 537 TPRGHIIASCDARGVTK 553 Score = 46.2 bits (108), Expect = 7e-05 Identities = 23/85 (27%), Positives = 40/85 (47%) Frame = +3 Query: 345 KIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHT 524 K+ + + V+ T +GH + HP G A+ S D+ +K+WD+ K C T +GH Sbjct: 385 KMVGLPQGNVLLTGSGHTDWLSGCCFHPSGSKLATSSGDSTIKLWDLNKGECTLTLEGHN 444 Query: 525 GRIDVLRFTPDGRWIVSGGADSSVK 599 + + G ++ S D + K Sbjct: 445 HAVWSCTWHSCGDFVASASLDMTSK 469 Score = 45.1 bits (105), Expect = 2e-04 Identities = 30/130 (23%), Positives = 49/130 (37%) Frame = +3 Query: 207 DQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTF 386 D +W V +L G T V S+ F ++ +A T+ +WD K ++ Sbjct: 465 DMTSKIWDVNSERCRYTLYGHTDSVNSIEFFPFSNILLTASADKTLSVWDARTGKCEQSL 524 Query: 387 TGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRW 566 GH + P G AS + K+WD RK I + + + F GR Sbjct: 525 YGHMHSVNDATFTPRGHIIASCDARGVTKLWDFRKLIPIVSIDVGPSSGNEVNFDQSGRV 584 Query: 567 IVSGGADSSV 596 + A+ + Sbjct: 585 LAQASANGII 594 Score = 44.3 bits (103), Expect = 3e-04 Identities = 31/140 (22%), Positives = 61/140 (43%) Frame = +3 Query: 180 SRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDI 359 S L+T D+ +++W SL G V +F +I + A G K+WD Sbjct: 498 SNILLTASADKTLSVWDARTGKCEQSLYGHMHSVNDATFTPRGHIIASCDARGVTKLWDF 557 Query: 360 EEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDV 539 + + + S+ ++ G A S++ + + D++ + IH GH + Sbjct: 558 RKLIPIVSIDVGPSSGNEVNFDQSGRVLAQASANGIIHLLDLKSGQ-IHKLVGHESEVHS 616 Query: 540 LRFTPDGRWIVSGGADSSVK 599 + F+ G + SGG+D +++ Sbjct: 617 VVFSHLGENLYSGGSDGTIR 636 Score = 40.4 bits (93), Expect = 0.004 Identities = 31/121 (25%), Positives = 51/121 (42%), Gaps = 2/121 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQK--VNLWAVGKPTAVLSLSGLTSPVESLSF 296 Q H V A F T R I D + LW K ++S+ S ++F Sbjct: 522 QSLYGHMHSVNDATF---TPRGHIIASCDARGVTKLWDFRKLIPIVSIDVGPSSGNEVNF 578 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 D S ++ +A+G I + D++ + + GH S S+ G+ SG SD +++ Sbjct: 579 DQSGRVLAQASANGIIHLLDLKSGQ-IHKLVGHESEVHSVVFSHLGENLYSGGSDGTIRL 637 Query: 477 W 479 W Sbjct: 638 W 638 Score = 33.5 bits (75), Expect = 0.48 Identities = 20/77 (25%), Positives = 33/77 (42%) Frame = +3 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 K+ F H + + HP D+ S S D K+ + + + T GHT + F Sbjct: 351 KLNNIFRLHELPVSCIVMHPCRDYLISCSEDRLWKMVGLPQGNVLLTGSGHTDWLSGCCF 410 Query: 549 TPDGRWIVSGGADSSVK 599 P G + + DS++K Sbjct: 411 HPSGSKLATSSGDSTIK 427
>PRP46_CANGA (Q6FJZ9) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 427 Score = 79.3 bits (194), Expect = 8e-15 Identities = 39/154 (25%), Positives = 71/154 (46%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMI 317 H V C K + TG D+ + +W + ++L V L+ + + Sbjct: 114 HHGWVRCIAMDKVDNEWFATGSNDKTIKIWNLASGKLKVTLKAHDMTVRDLAISNRHPYM 173 Query: 318 GAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKR 497 + + T+K WD+E+ +R + GH S ++D HP D + D+ +K+WD+R + Sbjct: 174 FSVSEDKTVKCWDLEKNTAIRNYHGHLSGVHTVDIHPTVDVVVTAGRDSVVKVWDIRTRL 233 Query: 498 CIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 + T GH G I +R P ++S D+S++ Sbjct: 234 PVMTLPGHKGPITKVRCLPVDPQVISSSVDASIR 267 Score = 48.9 bits (115), Expect = 1e-05 Identities = 24/94 (25%), Positives = 42/94 (44%) Frame = +3 Query: 204 EDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRT 383 ED+ V W + K TA+ + G S V ++ + ++ +K+WDI V T Sbjct: 178 EDKTVKCWDLEKNTAIRNYHGHLSGVHTVDIHPTVDVVVTAGRDSVVKVWDIRTRLPVMT 237 Query: 384 FTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDM 485 GH+ + P S S D ++++WD+ Sbjct: 238 LPGHKGPITKVRCLPVDPQVISSSVDASIRLWDL 271 Score = 45.4 bits (106), Expect = 1e-04 Identities = 23/105 (21%), Positives = 49/105 (46%) Frame = +3 Query: 177 TSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWD 356 T ++T G D V +W + V++L G P+ + + + + + +I++WD Sbjct: 211 TVDVVVTAGRDSVVKVWDIRTRLPVMTLPGHKGPITKVRCLPVDPQVISSSVDASIRLWD 270 Query: 357 IEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRK 491 + K ++ T H+ + HP FAS ++ +++ W + K Sbjct: 271 LVAGKSMKVLTHHQRTVRDISVHPSEFSFASACTN-DIRSWLLPK 314
>RCO1_NEUCR (P78706) Transcriptional repressor rco-1| Length = 604 Score = 78.6 bits (192), Expect = 1e-14 Identities = 48/173 (27%), Positives = 85/173 (49%), Gaps = 16/173 (9%) Frame = +3 Query: 129 FVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAV--GKPTAVLSLSGLTSPVESLSFDS 302 F H D+ F R RT+ +G D+ V LW + G+ T+VLS+ V +++ Sbjct: 382 FHGHEQDIYSLDFS-RDGRTIASGSGDRTVRLWDIETGQNTSVLSIE---DGVTTVAISP 437 Query: 303 SEVMIGAGAASGTIKIWDIEE--AKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 + + AG+ ++++WD+ A+ + GH+ + S+ P G SGS D +K+ Sbjct: 438 DKQFVAAGSLDKSVRVWDMRGYLAERLEGPDGHKDSVYSVAFSPDGRNLVSGSLDKTIKM 497 Query: 477 WDM------------RKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 W++ + RCI T++GH + + TPD +W++SG D V+ Sbjct: 498 WELSAPRGIPSSAPPKGGRCIKTFEGHRDFVLSVALTPDSQWVLSGSKDRGVQ 550 Score = 72.0 bits (175), Expect = 1e-12 Identities = 43/146 (29%), Positives = 70/146 (47%), Gaps = 9/146 (6%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L TG ED+ + +W + T + G + SL F I +G+ T+++WDIE Sbjct: 359 LATGAEDKLIRVWDIQSRTIRNTFHGHEQDIYSLDFSRDGRTIASGSGDRTVRLWDIE-- 416 Query: 369 KVVRTFTGHRSNCASLDS-------HPFGDFFASGSSDTNMKIWDMR--KKRCIHTYQGH 521 TG ++ S++ P F A+GS D ++++WDMR + GH Sbjct: 417 ------TGQNTSVLSIEDGVTTVAISPDKQFVAAGSLDKSVRVWDMRGYLAERLEGPDGH 470 Query: 522 TGRIDVLRFTPDGRWIVSGGADSSVK 599 + + F+PDGR +VSG D ++K Sbjct: 471 KDSVYSVAFSPDGRNLVSGSLDKTIK 496 Score = 59.3 bits (142), Expect = 8e-09 Identities = 30/107 (28%), Positives = 51/107 (47%) Frame = +3 Query: 279 VESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSS 458 + S+ F + GA I++WDI+ + TF GH + SLD G ASGS Sbjct: 347 IRSVCFSPDGKYLATGAEDKLIRVWDIQSRTIRNTFHGHEQDIYSLDFSRDGRTIASGSG 406 Query: 459 DTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 D +++WD+ + G + + +PD +++ +G D SV+ Sbjct: 407 DRTVRLWDIETGQNTSVLSIEDG-VTTVAISPDKQFVAAGSLDKSVR 452 Score = 37.4 bits (85), Expect = 0.033 Identities = 24/116 (20%), Positives = 45/116 (38%), Gaps = 17/116 (14%) Frame = +3 Query: 183 RTLITGGEDQKVNLWAVGKPTAVLS------------LSGLTSPVESLSFDSSEVMIGAG 326 R L++G D+ + +W + P + S G V S++ + +G Sbjct: 484 RNLVSGSLDKTIKMWELSAPRGIPSSAPPKGGRCIKTFEGHRDFVLSVALTPDSQWVLSG 543 Query: 327 AASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGD-----FFASGSSDTNMKIW 479 + ++ WD GH+++ S+ P +FA+GS D +IW Sbjct: 544 SKDRGVQFWDPRTGHTQLMLQGHKNSVISVAPSPVTGPNGVGYFATGSGDMRARIW 599
>WDS_DROME (Q9V3J8) Protein will die slowly| Length = 361 Score = 78.2 bits (191), Expect = 2e-14 Identities = 42/167 (25%), Positives = 80/167 (47%), Gaps = 1/167 (0%) Frame = +3 Query: 90 SRMATKRAYKLQEFVA-HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSG 266 S ++ K Y L+ +A H V+ KF L + D+ + +W ++SG Sbjct: 54 SSLSVKPNYTLKFTLAGHTKAVSAVKFSPN-GEWLASSSADKLIKIWGAYDGKFEKTISG 112 Query: 267 LTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFA 446 + +++ S ++ +G+ T+K+W++ K ++T GH + + +P + Sbjct: 113 HKLGISDVAWSSDSRLLVSGSDDKTLKVWELSTGKSLKTLKGHSNYVFCCNFNPQSNLIV 172 Query: 447 SGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGAD 587 SGS D +++IWD+R +C+ T H+ + + F DG IVS D Sbjct: 173 SGSFDESVRIWDVRTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYD 219 Score = 74.3 bits (181), Expect = 2e-13 Identities = 43/163 (26%), Positives = 76/163 (46%), Gaps = 4/163 (2%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 L+ H++ V C F + S +++G D+ V +W V + +L + PV ++ F+ Sbjct: 149 LKTLKGHSNYVFCCNFNPQ-SNLIVSGSFDESVRIWDVRTGKCLKTLPAHSDPVSAVHFN 207 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCAS-LDSHPFGDFFASGSSDTNMKI 476 +I + + G +IWD + ++T + S + P G + + + D +K+ Sbjct: 208 RDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKL 267 Query: 477 WDMRKKRCIHTYQGHTGR---IDVLRFTPDGRWIVSGGADSSV 596 WD K +C+ TY GH I G+WIVSG D+ V Sbjct: 268 WDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNMV 310 Score = 70.5 bits (171), Expect = 4e-12 Identities = 33/141 (23%), Positives = 75/141 (53%), Gaps = 1/141 (0%) Frame = +3 Query: 180 SRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDI 359 SR L++G +D+ + +W + ++ +L G ++ V +F+ +I +G+ +++IWD+ Sbjct: 126 SRLLVSGSDDKTLKVWELSTGKSLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDV 185 Query: 360 EEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHT-YQGHTGRID 536 K ++T H +++ + G S S D +IWD +C+ T + Sbjct: 186 RTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVS 245 Query: 537 VLRFTPDGRWIVSGGADSSVK 599 ++F+P+G++I++ D+++K Sbjct: 246 FVKFSPNGKYILAATLDNTLK 266 Score = 67.8 bits (164), Expect = 2e-11 Identities = 37/144 (25%), Positives = 64/144 (44%) Frame = +3 Query: 168 GKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIK 347 G+ + T K +L T +L+G T V ++ F + + + +A IK Sbjct: 38 GQPGATTSSNSSASNKSSLSVKPNYTLKFTLAGHTKAVSAVKFSPNGEWLASSSADKLIK 97 Query: 348 IWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTG 527 IW + K +T +GH+ + + SGS D +K+W++ + + T +GH+ Sbjct: 98 IWGAYDGKFEKTISGHKLGISDVAWSSDSRLLVSGSDDKTLKVWELSTGKSLKTLKGHSN 157 Query: 528 RIDVLRFTPDGRWIVSGGADSSVK 599 + F P IVSG D SV+ Sbjct: 158 YVFCCNFNPQSNLIVSGSFDESVR 181 Score = 60.5 bits (145), Expect = 4e-09 Identities = 37/142 (26%), Positives = 64/142 (45%), Gaps = 4/142 (2%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSL-SGLTSPVESLSF 296 L+ AH+ V+ F R +++ D +W + +L PV + F Sbjct: 191 LKTLPAHSDPVSAVHFN-RDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKF 249 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSN--CASLD-SHPFGDFFASGSSDTN 467 + I A T+K+WD + K ++T+TGH++ C + S G + SGS D Sbjct: 250 SPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNM 309 Query: 468 MKIWDMRKKRCIHTYQGHTGRI 533 + IW+++ K + QGHT + Sbjct: 310 VYIWNLQSKEVVQKLQGHTDTV 331 Score = 33.5 bits (75), Expect = 0.48 Identities = 21/96 (21%), Positives = 41/96 (42%), Gaps = 5/96 (5%) Frame = +3 Query: 207 DQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEV---MIGAGAASGTIKIWDIEEAKVV 377 D + LW K + + +G + + + S I +G+ + IW+++ +VV Sbjct: 262 DNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNMVYIWNLQSKEVV 321 Query: 378 RTFTGHRSNCASLDSHPFGDFFASGS--SDTNMKIW 479 + GH HP + AS + +D +K+W Sbjct: 322 QKLQGHTDTVLCTACHPTENIIASAALENDKTIKLW 357
>TAF5_SCHPO (O13282) Transcription initiation factor TFIID subunit 5| (Transcription initiation factor TFIID 72 kDa subunit) (TAFII-72) Length = 643 Score = 78.2 bits (191), Expect = 2e-14 Identities = 40/171 (23%), Positives = 77/171 (45%) Frame = +3 Query: 84 LPSRMATKRAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLS 263 LP + + + ++H+ V F ++ L++ ED LW+V TA+++ Sbjct: 360 LPKSTSVEDSDGSVRLLSHSGPVYGTTFSP-DNKYLLSCSEDASARLWSVDTKTALVAYK 418 Query: 264 GLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFF 443 G T PV ++F + T ++W + +R F GH S+ + HP + Sbjct: 419 GHTGPVWDVAFGPFGHYFATASHDQTAQLWSCDHIYPLRVFAGHLSDVDCVTFHPNSAYV 478 Query: 444 ASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 +GSSD ++WD+ + + + GHT + + PDG + S ++ + Sbjct: 479 LTGSSDKTCRLWDVHRGHSVRVFNGHTQPVTAVAIAPDGHTMASADSEGLI 529 Score = 77.0 bits (188), Expect = 4e-14 Identities = 44/151 (29%), Positives = 70/151 (46%) Frame = +3 Query: 147 DVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAG 326 DV FG T DQ LW+ + +G S V+ ++F + + G Sbjct: 426 DVAFGPFG----HYFATASHDQTAQLWSCDHIYPLRVFAGHLSDVDCVTFHPNSAYVLTG 481 Query: 327 AASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIH 506 ++ T ++WD+ VR F GH ++ P G AS S+ + +WD+ R I Sbjct: 482 SSDKTCRLWDVHRGHSVRVFNGHTQPVTAVAIAPDGHTMASADSEGLIHLWDIGTGRRIK 541 Query: 507 TYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 T +GH G I L F+ + +VSGG+D +V+ Sbjct: 542 TMRGHRGNIYSLSFSRESTVLVSGGSDCTVR 572 Score = 73.6 bits (179), Expect = 4e-13 Identities = 40/126 (31%), Positives = 60/126 (47%) Frame = +3 Query: 114 YKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLS 293 Y L+ F H SDV C F ++ L TG D+ LW V + +V +G T PV +++ Sbjct: 454 YPLRVFAGHLSDVDCVTFHPNSAYVL-TGSSDKTCRLWDVHRGHSVRVFNGHTQPVTAVA 512 Query: 294 FDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMK 473 + + + G I +WDI + ++T GHR N SL SG SD ++ Sbjct: 513 IAPDGHTMASADSEGLIHLWDIGTGRRIKTMRGHRGNIYSLSFSRESTVLVSGGSDCTVR 572 Query: 474 IWDMRK 491 WD+ K Sbjct: 573 AWDVFK 578 Score = 57.8 bits (138), Expect = 2e-08 Identities = 32/165 (19%), Positives = 72/165 (43%), Gaps = 13/165 (7%) Frame = +3 Query: 144 SDVTCAKFGKRTSRTLITGGEDQKVNLWAVG-------KPTAVLSLSGL------TSPVE 284 +++ CA+F S + G ++ + LW++ K T+V G + PV Sbjct: 325 NNMNCAEFSP-DSTMIACGFQESYIRLWSIKADKKSLPKSTSVEDSDGSVRLLSHSGPVY 383 Query: 285 SLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDT 464 +F + + + + ++W ++ + + GH + PFG +FA+ S D Sbjct: 384 GTTFSPDNKYLLSCSEDASARLWSVDTKTALVAYKGHTGPVWDVAFGPFGHYFATASHDQ 443 Query: 465 NMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 ++W + + GH +D + F P+ ++++G +D + + Sbjct: 444 TAQLWSCDHIYPLRVFAGHLSDVDCVTFHPNSAYVLTGSSDKTCR 488
>PRL1_ARATH (Q42384) PP1/PP2A phosphatases pleiotropic regulator PRL1| Length = 486 Score = 77.0 bits (188), Expect = 4e-14 Identities = 38/135 (28%), Positives = 65/135 (48%) Frame = +3 Query: 195 TGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKV 374 TG D+ + +W V L+L+G V L+ + + + +K WD+E+ KV Sbjct: 193 TGSADRTIKIWDVATGVLKLTLTGHIEQVRGLAVSNRHTYMFSAGDDKQVKCWDLEQNKV 252 Query: 375 VRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTP 554 +R++ GH S L HP D +G D+ ++WD+R K I GH + + P Sbjct: 253 IRSYHGHLSGVYCLALHPTLDVLLTGGRDSVCRVWDIRTKMQIFALSGHDNTVCSVFTRP 312 Query: 555 DGRWIVSGGADSSVK 599 +V+G D+++K Sbjct: 313 TDPQVVTGSHDTTIK 327 Score = 65.9 bits (159), Expect = 9e-11 Identities = 42/159 (26%), Positives = 73/159 (45%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 ++ + H S V C T L+TGG D +W + + +LSG + V S+ Sbjct: 253 IRSYHGHLSGVYCLALHP-TLDVLLTGGRDSVCRVWDIRTKMQIFALSGHDNTVCSVFTR 311 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 ++ + G+ TIK WD+ K + T T H+ + ++ HP + FAS S+D K Sbjct: 312 PTDPQVVTGSHDTTIKFWDLRYGKTMSTLTHHKKSVRAMTLHPKENAFASASADNTKKFS 371 Query: 480 DMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 + + C + I+ + DG +V+GG + S+ Sbjct: 372 LPKGEFCHNMLSQQKTIINAMAVNEDG-VMVTGGDNGSI 409 Score = 62.4 bits (150), Expect = 1e-09 Identities = 33/104 (31%), Positives = 48/104 (46%) Frame = +3 Query: 279 VESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSS 458 V S++FD S G+A TIKIWD+ + T TGH L + S Sbjct: 179 VRSVAFDPSNEWFCTGSADRTIKIWDVATGVLKLTLTGHIEQVRGLAVSNRHTYMFSAGD 238 Query: 459 DTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADS 590 D +K WD+ + + I +Y GH + L P +++GG DS Sbjct: 239 DKQVKCWDLEQNKVIRSYHGHLSGVYCLALHPTLDVLLTGGRDS 282 Score = 60.8 bits (146), Expect = 3e-09 Identities = 32/137 (23%), Positives = 60/137 (43%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 + + G+D++V W + + + S G S V L+ + ++ G ++WDI Sbjct: 233 MFSAGDDKQVKCWDLEQNKVIRSYHGHLSGVYCLALHPTLDVLLTGGRDSVCRVWDIRTK 292 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 + +GH + S+ + P +GS DT +K WD+R + + T H + + Sbjct: 293 MQIFALSGHDNTVCSVFTRPTDPQVVTGSHDTTIKFWDLRYGKTMSTLTHHKKSVRAMTL 352 Query: 549 TPDGRWIVSGGADSSVK 599 P S AD++ K Sbjct: 353 HPKENAFASASADNTKK 369 Score = 39.3 bits (90), Expect = 0.009 Identities = 23/77 (29%), Positives = 35/77 (45%) Frame = +3 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 K R GH S+ P ++F +GS+D +KIWD+ T GH ++ L Sbjct: 167 KNYRVIQGHLGWVRSVAFDPSNEWFCTGSADRTIKIWDVATGVLKLTLTGHIEQVRGLAV 226 Query: 549 TPDGRWIVSGGADSSVK 599 + ++ S G D VK Sbjct: 227 SNRHTYMFSAGDDKQVK 243
>TAF5_DROME (P49846) Transcription initiation factor TFIID subunit 5| (Transcription initiation factor TFIID 85 kDa subunit) (p85) (TAFII-80) Length = 704 Score = 77.0 bits (188), Expect = 4e-14 Identities = 38/130 (29%), Positives = 65/130 (50%) Frame = +3 Query: 207 DQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTF 386 D+ LWA A+ G S V+ + F + + G++ T+++WD + VR Sbjct: 513 DKTARLWATDSNQALRVFVGHLSDVDCVQFHPNSNYVATGSSDRTVRLWDNMTGQSVRLM 572 Query: 387 TGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRW 566 TGH+ + +SL G + ASGS D N+ IWD+ + T HT + + F+ DG Sbjct: 573 TGHKGSVSSLAFSACGRYLASGSVDHNIIIWDLSNGSLVTTLLRHTSTVTTITFSRDGTV 632 Query: 567 IVSGGADSSV 596 + + G D+++ Sbjct: 633 LAAAGLDNNL 642 Score = 68.9 bits (167), Expect = 1e-11 Identities = 40/131 (30%), Positives = 59/131 (45%) Frame = +3 Query: 99 ATKRAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSP 278 AT L+ FV H SDV C +F S + TG D+ V LW +V ++G Sbjct: 520 ATDSNQALRVFVGHLSDVDCVQFHPN-SNYVATGSSDRTVRLWDNMTGQSVRLMTGHKGS 578 Query: 279 VESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSS 458 V SL+F + + +G+ I IWD+ +V T H S ++ G A+ Sbjct: 579 VSSLAFSACGRYLASGSVDHNIIIWDLSNGSLVTTLLRHTSTVTTITFSRDGTVLAAAGL 638 Query: 459 DTNMKIWDMRK 491 D N+ +WD K Sbjct: 639 DNNLTLWDFHK 649 Score = 58.5 bits (140), Expect = 1e-08 Identities = 29/115 (25%), Positives = 55/115 (47%) Frame = +3 Query: 255 SLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFG 434 SL G T PV +F ++ + + TI++W + V T+ GH + P G Sbjct: 445 SLMGHTGPVYRCAFAPEMNLLLSCSEDSTIRLWSLLTWSCVVTYRGHVYPVWDVRFAPHG 504 Query: 435 DFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 +F S S D ++W + + + GH +D ++F P+ ++ +G +D +V+ Sbjct: 505 YYFVSCSYDKTARLWATDSNQALRVFVGHLSDVDCVQFHPNSNYVATGSSDRTVR 559 Score = 52.0 bits (123), Expect = 1e-06 Identities = 37/150 (24%), Positives = 66/150 (44%) Frame = +3 Query: 150 VTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGA 329 VTCA+ S L G D V +W++ P + +L S + L +S+++ Sbjct: 380 VTCAEISD-DSTMLACGFGDSSVRIWSL-TPAKLRTLKDADS-LRELDKESADI------ 430 Query: 330 ASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHT 509 +++ D +V R+ GH P + S S D+ +++W + C+ T Sbjct: 431 ---NVRMLDDRSGEVTRSLMGHTGPVYRCAFAPEMNLLLSCSEDSTIRLWSLLTWSCVVT 487 Query: 510 YQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 Y+GH + +RF P G + VS D + + Sbjct: 488 YRGHVYPVWDVRFAPHGYYFVSCSYDKTAR 517
>PKWA_THECU (P49695) Probable serine/threonine-protein kinase pkwA (EC| 2.7.11.1) Length = 742 Score = 77.0 bits (188), Expect = 4e-14 Identities = 37/139 (26%), Positives = 70/139 (50%), Gaps = 1/139 (0%) Frame = +3 Query: 186 TLITGGE-DQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIE 362 +L+ GG D+ +++W V + +L G T V +++F ++ +G+ T+++WD+ Sbjct: 472 SLLAGGSGDKLIHVWDVASGDELHTLEGHTDWVRAVAFSPDGALLASGSDDATVRLWDVA 531 Query: 363 EAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVL 542 A+ F GH + P G ASGS D ++W++ +GHT + + Sbjct: 532 AAEERAVFEGHTHYVLDIAFSPDGSMVASGSRDGTARLWNVATGTEHAVLKGHTDYVYAV 591 Query: 543 RFTPDGRWIVSGGADSSVK 599 F+PDG + SG D +++ Sbjct: 592 AFSPDGSMVASGSRDGTIR 610 Score = 71.2 bits (173), Expect = 2e-12 Identities = 49/177 (27%), Positives = 78/177 (44%), Gaps = 7/177 (3%) Frame = +3 Query: 90 SRMATKRAYKLQEFVAHA-----SDVTCAKFGKRTSRTLITGGEDQKVNLW--AVGKPTA 248 SR T R + + HA +D A + +G D + LW A GK Sbjct: 562 SRDGTARLWNVATGTEHAVLKGHTDYVYAVAFSPDGSMVASGSRDGTIRLWDVATGKERD 621 Query: 249 VLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHP 428 VL V SL+F M+ G+ S T+ +WD+ + + TF GH ++ P Sbjct: 622 VLQAPA--ENVVSLAFSPDGSMLVHGSDS-TVHLWDVASGEALHTFEGHTDWVRAVAFSP 678 Query: 429 FGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 G ASGS D +++WD+ + T +GHT + + F P+G + S D +++ Sbjct: 679 DGALLASGSDDRTIRLWDVAAQEEHTTLEGHTEPVHSVAFHPEGTTLASASEDGTIR 735 Score = 65.5 bits (158), Expect = 1e-10 Identities = 38/136 (27%), Positives = 61/136 (44%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L +G +D V LW V G T V ++F M+ +G+ GT ++W++ Sbjct: 516 LASGSDDATVRLWDVAAAEERAVFEGHTHYVLDIAFSPDGSMVASGSRDGTARLWNVATG 575 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 GH ++ P G ASGS D +++WD+ + Q + L F Sbjct: 576 TEHAVLKGHTDYVYAVAFSPDGSMVASGSRDGTIRLWDVATGKERDVLQAPAENVVSLAF 635 Query: 549 TPDGRWIVSGGADSSV 596 +PDG +V G+DS+V Sbjct: 636 SPDGSMLVH-GSDSTV 650 Score = 61.6 bits (148), Expect = 2e-09 Identities = 27/105 (25%), Positives = 50/105 (47%) Frame = +3 Query: 285 SLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDT 464 +++F ++ G+ I +WD+ + T GH ++ P G ASGS D Sbjct: 464 AVAFSPGGSLLAGGSGDKLIHVWDVASGDELHTLEGHTDWVRAVAFSPDGALLASGSDDA 523 Query: 465 NMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 +++WD+ ++GHT + + F+PDG + SG D + + Sbjct: 524 TVRLWDVAAAEERAVFEGHTHYVLDIAFSPDGSMVASGSRDGTAR 568 Score = 60.5 bits (145), Expect = 4e-09 Identities = 29/98 (29%), Positives = 49/98 (50%) Frame = +3 Query: 186 TLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEE 365 +++ G D V+LW V A+ + G T V +++F ++ +G+ TI++WD+ Sbjct: 640 SMLVHGSDSTVHLWDVASGEALHTFEGHTDWVRAVAFSPDGALLASGSDDRTIRLWDVAA 699 Query: 366 AKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 + T GH S+ HP G AS S D ++IW Sbjct: 700 QEEHTTLEGHTEPVHSVAFHPEGTTLASASEDGTIRIW 737 Score = 43.9 bits (102), Expect = 4e-04 Identities = 24/80 (30%), Positives = 35/80 (43%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 L F H V F L +G +D+ + LW V +L G T PV S++F Sbjct: 661 LHTFEGHTDWVRAVAFSP-DGALLASGSDDRTIRLWDVAAQEEHTTLEGHTEPVHSVAFH 719 Query: 300 SSEVMIGAGAASGTIKIWDI 359 + + + GTI+IW I Sbjct: 720 PEGTTLASASEDGTIRIWPI 739
>SPG16_HUMAN (Q8N0X2) Sperm-associated antigen 16 protein (PF20 protein homolog)| Length = 631 Score = 77.0 bits (188), Expect = 4e-14 Identities = 47/162 (29%), Positives = 74/162 (45%), Gaps = 1/162 (0%) Frame = +3 Query: 114 YKLQE-FVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESL 290 YKL+ F H V+C L++ GED+ + + K +L+ G T + Sbjct: 342 YKLKNIFRLHELPVSCVSMQPHKD-ILVSCGEDRLWKVLGLPKCNVLLTGFGHTDWLSDC 400 Query: 291 SFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNM 470 F S + + T+K+WD+ + TF GH S H G+F AS S D Sbjct: 401 CFHPSGDKLATSSGDTTVKLWDLCTGDCILTFEGHSRAVWSCTWHSCGNFVASSSLDKTS 460 Query: 471 KIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 KIWD+ +RC T GHT ++ + F P +++ AD ++ Sbjct: 461 KIWDVNSERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTL 502 Score = 66.2 bits (160), Expect = 7e-11 Identities = 37/129 (28%), Positives = 57/129 (44%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L T D V LW + +L+ G + V S ++ S + + + T KIWD+ Sbjct: 409 LATSSGDTTVKLWDLCTGDCILTFEGHSRAVWSCTWHSCGNFVASSSLDKTSKIWDVNSE 468 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 + T GH + S++ PF + + S+D + IWD R C + GH I+ F Sbjct: 469 RCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTGICEQSLYGHMHSINDAIF 528 Query: 549 TPDGRWIVS 575 P G I S Sbjct: 529 DPRGHMIAS 537 Score = 52.4 bits (124), Expect = 1e-06 Identities = 35/140 (25%), Positives = 59/140 (42%) Frame = +3 Query: 180 SRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDI 359 S TL+T D+ +++W SL G + FD MI + A G K+WD Sbjct: 490 SNTLLTSSADKTLSIWDARTGICEQSLYGHMHSINDAIFDPRGHMIASCDACGVTKLWDF 549 Query: 360 EEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDV 539 + + + S ++ G A S + + + D++ IH GH Sbjct: 550 RKLLPIVSIDIGPSPGNEVNFDSSGRVLAQASGNGVIHLLDLKSGE-IHKLMGHENEAHT 608 Query: 540 LRFTPDGRWIVSGGADSSVK 599 + F+ DG + SGG+D +V+ Sbjct: 609 VVFSHDGEILFSGGSDGTVR 628 Score = 51.2 bits (121), Expect = 2e-06 Identities = 28/108 (25%), Positives = 50/108 (46%) Frame = +3 Query: 276 PVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGS 455 PV +S + ++ + K+ + + V+ T GH + HP GD A+ S Sbjct: 354 PVSCVSMQPHKDILVSCGEDRLWKVLGLPKCNVLLTGFGHTDWLSDCCFHPSGDKLATSS 413 Query: 456 SDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 DT +K+WD+ CI T++GH+ + + G ++ S D + K Sbjct: 414 GDTTVKLWDLCTGDCILTFEGHSRAVWSCTWHSCGNFVASSSLDKTSK 461 Score = 38.9 bits (89), Expect = 0.011 Identities = 21/86 (24%), Positives = 41/86 (47%) Frame = +3 Query: 222 LWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRS 401 LW K ++S+ SP ++FDSS ++ + +G I + D++ + + GH + Sbjct: 546 LWDFRKLLPIVSIDIGPSPGNEVNFDSSGRVLAQASGNGVIHLLDLKSGE-IHKLMGHEN 604 Query: 402 NCASLDSHPFGDFFASGSSDTNMKIW 479 ++ G+ SG SD ++ W Sbjct: 605 EAHTVVFSHDGEILFSGGSDGTVRTW 630 Score = 29.6 bits (65), Expect = 6.9 Identities = 19/77 (24%), Positives = 30/77 (38%) Frame = +3 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 K+ F H + + P D S D K+ + K + T GHT + F Sbjct: 343 KLKNIFRLHELPVSCVSMQPHKDILVSCGEDRLWKVLGLPKCNVLLTGFGHTDWLSDCCF 402 Query: 549 TPDGRWIVSGGADSSVK 599 P G + + D++VK Sbjct: 403 HPSGDKLATSSGDTTVK 419
>GBB1_CRIGR (Q6TMK6) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 76.6 bits (187), Expect = 5e-14 Identities = 44/157 (28%), Positives = 75/157 (47%), Gaps = 2/157 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 +E H ++C +F ++T ED LW + + +G T V SLS Sbjct: 136 RELAGHTGYLSCCRF--LNDNQIVTSSEDTTCALWDIETGQQTTTFTGHTGDVMSLSLAP 193 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 + +GA + K+WD+ E +TFTGH S+ ++ P G+ FA+GS D +++D Sbjct: 194 DTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFD 253 Query: 483 MRKKRCIHTYQGHT--GRIDVLRFTPDGRWIVSGGAD 587 +R + + TY I + F+ GR +++G D Sbjct: 254 LRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDD 290 Score = 68.9 bits (167), Expect = 1e-11 Identities = 31/87 (35%), Positives = 47/87 (54%) Frame = +3 Query: 339 TIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQG 518 T +WDIE + TFTGH + SL P F SG+ D + K+WD+R+ C T+ G Sbjct: 164 TCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTG 223 Query: 519 HTGRIDVLRFTPDGRWIVSGGADSSVK 599 H I+ + F P+G +G D++ + Sbjct: 224 HESDINAICFFPNGNAFATGSDDATCR 250 Score = 56.2 bits (134), Expect = 7e-08 Identities = 44/176 (25%), Positives = 76/176 (43%), Gaps = 7/176 (3%) Frame = +3 Query: 93 RMATKRAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLT 272 +M T+R + H + + +G SR L++ +D K+ +W V ++ + Sbjct: 43 QMRTRRTLR-----GHLAKIYAMHWGT-DSRLLVSASQDGKLIIWDSYTTNKVHAIPLRS 96 Query: 273 SPVESLSFDSSEVMIGAGAASGTIKIWDIE----EAKVVRTFTGHR---SNCASLDSHPF 431 S V + ++ S + G I++++ +V R GH S C L+ + Sbjct: 97 SWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLNDNQI 156 Query: 432 GDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 + S DT +WD+ + T+ GHTG + L PD R VSG D+S K Sbjct: 157 ----VTSSEDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAK 208 Score = 43.1 bits (100), Expect = 6e-04 Identities = 31/122 (25%), Positives = 51/122 (41%), Gaps = 2/122 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLS--GLTSPVESLSF 296 Q F H SD+ F TG +D L+ + +++ S + + S+SF Sbjct: 219 QTFTGHESDINAICFFPN-GNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSF 277 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 S ++ AG +WD +A GH + + L G A+GS D+ +KI Sbjct: 278 SKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKI 337 Query: 477 WD 482 W+ Sbjct: 338 WN 339
>PRP46_EMENI (Q5BE22) Pre-mRNA-splicing factor prp46 (Pre-mRNA-processing| protein 46) Length = 452 Score = 76.6 bits (187), Expect = 5e-14 Identities = 38/135 (28%), Positives = 66/135 (48%) Frame = +3 Query: 195 TGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKV 374 +G D+ + +W + L+L+G S V L+ + + +K WD+E KV Sbjct: 160 SGAGDRTIKIWNLATGALRLTLTGHISTVRGLAVSPRHPYLFSCGEDKMVKCWDLETNKV 219 Query: 375 VRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTP 554 +R + GH S +L HP D +G D ++WDMR + IH GHTG + ++ Sbjct: 220 IRHYHGHLSGVYTLALHPRLDLLVTGGRDGVARVWDMRTRSNIHVLSGHTGTVADVQCQE 279 Query: 555 DGRWIVSGGADSSVK 599 +++G D++V+ Sbjct: 280 ADPQVITGSLDATVR 294 Score = 63.9 bits (154), Expect = 3e-10 Identities = 37/136 (27%), Positives = 64/136 (47%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L+TGG D +W + + + LSG T V + ++ + G+ T+++WD+ Sbjct: 242 LVTGGRDGVARVWDMRTRSNIHVLSGHTGTVADVQCQEADPQVITGSLDATVRLWDLAAG 301 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 K + T H+ SL +HP FAS S+ ++K W + ++GH I+ L Sbjct: 302 KTMGVLTHHKKGIRSLATHPREFTFASASTG-SIKQWKCPGGEFMQNFEGHNAIINTLSV 360 Query: 549 TPDGRWIVSGGADSSV 596 D + SGG + S+ Sbjct: 361 NED-NVLFSGGDNGSM 375 Score = 59.7 bits (143), Expect = 6e-09 Identities = 34/110 (30%), Positives = 49/110 (44%) Frame = +3 Query: 258 LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGD 437 +SG V SL+ + + +GA TIKIW++ + T TGH S L P Sbjct: 139 ISGHLGWVRSLAVEPNNEWFASGAGDRTIKIWNLATGALRLTLTGHISTVRGLAVSPRHP 198 Query: 438 FFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGAD 587 + S D +K WD+ + I Y GH + L P +V+GG D Sbjct: 199 YLFSCGEDKMVKCWDLETNKVIRHYHGHLSGVYTLALHPRLDLLVTGGRD 248 Score = 46.2 bits (108), Expect = 7e-05 Identities = 25/77 (32%), Positives = 38/77 (49%) Frame = +3 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 K++R +GH SL P ++FASG+ D +KIW++ T GH + L Sbjct: 134 KLMRVISGHLGWVRSLAVEPNNEWFASGAGDRTIKIWNLATGALRLTLTGHISTVRGLAV 193 Query: 549 TPDGRWIVSGGADSSVK 599 +P ++ S G D VK Sbjct: 194 SPRHPYLFSCGEDKMVK 210 Score = 45.4 bits (106), Expect = 1e-04 Identities = 26/122 (21%), Positives = 47/122 (38%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L + GED+ V W + + G S V +L+ ++ G G ++WD+ Sbjct: 200 LFSCGEDKMVKCWDLETNKVIRHYHGHLSGVYTLALHPRLDLLVTGGRDGVARVWDMRTR 259 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 + +GH A + +GS D +++WD+ + + H I L Sbjct: 260 SNIHVLSGHTGTVADVQCQEADPQVITGSLDATVRLWDLAAGKTMGVLTHHKKGIRSLAT 319 Query: 549 TP 554 P Sbjct: 320 HP 321
>SEL10_CAEEL (Q93794) F-box/WD-repeat protein sel-10 (Suppressor/enhancer of| lin-12) (Sel-10 protein) Length = 587 Score = 76.6 bits (187), Expect = 5e-14 Identities = 41/139 (29%), Positives = 69/139 (49%), Gaps = 2/139 (1%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L+TG +D + +W + K + +L G T V + I +G+ T+K+W + Sbjct: 269 LVTGSDDNTLKVWCIDKGEVMYTLVGHTGGVWTSQISQCGRYIVSGSTDRTVKVWSTVDG 328 Query: 369 KVVRTFTGHRS--NCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVL 542 ++ T GH S C ++ G +GS DT +++WD+ R + T GH + + Sbjct: 329 SLLHTLQGHTSTVRCMAM----AGSILVTGSRDTTLRVWDVESGRHLATLHGHHAAVRCV 384 Query: 543 RFTPDGRWIVSGGADSSVK 599 +F DG +VSGG D +VK Sbjct: 385 QF--DGTTVVSGGYDFTVK 401 Score = 75.1 bits (183), Expect = 1e-13 Identities = 48/163 (29%), Positives = 74/163 (45%), Gaps = 3/163 (1%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 L H S V C L+TG D + +W V + +L G + V + FD Sbjct: 331 LHTLQGHTSTVRCMAMA---GSILVTGSRDTTLRVWDVESGRHLATLHGHHAAVRCVQFD 387 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 + V+ +G T+KIW+ + +RT TGH + SL SGS DT++++W Sbjct: 388 GTTVV--SGGYDFTVKIWNAHTGRCIRTLTGHNNRVYSLLFESERSIVCSGSLDTSIRVW 445 Query: 480 DMRK---KRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 D + + C+ QGHT ++ G +VS ADS V+ Sbjct: 446 DFTRPEGQECVALLQGHTSLTSGMQLR--GNILVSCNADSHVR 486 Score = 69.7 bits (169), Expect = 6e-12 Identities = 41/153 (26%), Positives = 78/153 (50%), Gaps = 3/153 (1%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMI 317 H + V C +F T+++GG D V +W + +L+G + V SL F+S ++ Sbjct: 377 HHAAVRCVQFD---GTTVVSGGYDFTVKIWNAHTGRCIRTLTGHNNRVYSLLFESERSIV 433 Query: 318 GAGAASGTIKIWDI---EEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMR 488 +G+ +I++WD E + V GH S + + G+ S ++D+++++WD+ Sbjct: 434 CSGSLDTSIRVWDFTRPEGQECVALLQGHTSLTSGMQLR--GNILVSCNADSHVRVWDIH 491 Query: 489 KKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGAD 587 + C+H GH I L++ GR +V+ +D Sbjct: 492 EGTCVHMLSGHRSAITSLQWF--GRNMVATSSD 522 Score = 47.8 bits (112), Expect = 2e-05 Identities = 25/76 (32%), Positives = 38/76 (50%) Frame = +3 Query: 372 VVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFT 551 V+R H C + D +GS D +K+W + K ++T GHTG + + + Sbjct: 250 VLRGHEDHVITCMQIHD----DVLVTGSDDNTLKVWCIDKGEVMYTLVGHTGGVWTSQIS 305 Query: 552 PDGRWIVSGGADSSVK 599 GR+IVSG D +VK Sbjct: 306 QCGRYIVSGSTDRTVK 321 Score = 42.4 bits (98), Expect = 0.001 Identities = 21/64 (32%), Positives = 34/64 (53%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L++ D V +W + + T V LSG S + SL + M+ + GT+K+WDIE Sbjct: 476 LVSCNADSHVRVWDIHEGTCVHMLSGHRSAITSLQWFGRN-MVATSSDDGTVKLWDIERG 534 Query: 369 KVVR 380 ++R Sbjct: 535 ALIR 538
>PRP46_ASPFU (Q4WT34) Pre-mRNA-splicing factor prp46 (Pre-mRNA-processing| protein 46) Length = 453 Score = 76.3 bits (186), Expect = 6e-14 Identities = 39/135 (28%), Positives = 65/135 (48%) Frame = +3 Query: 195 TGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKV 374 +G D+ + +W + L+L+G S V L+ + + +K WD+E KV Sbjct: 161 SGAGDRTIKIWNLATGALRLTLTGHISTVRGLAVSPRHPYLFSCGEDKMVKCWDLETNKV 220 Query: 375 VRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTP 554 +R + GH S +L HP D +G D ++WDMR + IH GH G + L+ Sbjct: 221 IRHYHGHLSGVYTLALHPRLDLLVTGGRDGVARVWDMRTRSNIHVLSGHKGTVADLKCQE 280 Query: 555 DGRWIVSGGADSSVK 599 I++G D++V+ Sbjct: 281 ADPQIITGSLDATVR 295 Score = 60.5 bits (145), Expect = 4e-09 Identities = 37/136 (27%), Positives = 63/136 (46%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L+TGG D +W + + + LSG V L ++ I G+ T+++WD+ Sbjct: 243 LVTGGRDGVARVWDMRTRSNIHVLSGHKGTVADLKCQEADPQIITGSLDATVRLWDLAAG 302 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 K + T H+ +L HP FAS S+ ++K W + + ++GH I+ L Sbjct: 303 KTMGVLTHHKKGVRNLAIHPREFTFASASTG-SIKQWKCPEGDFMQNFEGHNAVINSLAV 361 Query: 549 TPDGRWIVSGGADSSV 596 D + SGG + S+ Sbjct: 362 NED-NVLFSGGDNGSM 376 Score = 59.7 bits (143), Expect = 6e-09 Identities = 34/110 (30%), Positives = 49/110 (44%) Frame = +3 Query: 258 LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGD 437 +SG V SL+ + + +GA TIKIW++ + T TGH S L P Sbjct: 140 ISGHLGWVRSLAVEPNNEWFASGAGDRTIKIWNLATGALRLTLTGHISTVRGLAVSPRHP 199 Query: 438 FFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGAD 587 + S D +K WD+ + I Y GH + L P +V+GG D Sbjct: 200 YLFSCGEDKMVKCWDLETNKVIRHYHGHLSGVYTLALHPRLDLLVTGGRD 249 Score = 47.8 bits (112), Expect = 2e-05 Identities = 26/122 (21%), Positives = 48/122 (39%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L + GED+ V W + + G S V +L+ ++ G G ++WD+ Sbjct: 201 LFSCGEDKMVKCWDLETNKVIRHYHGHLSGVYTLALHPRLDLLVTGGRDGVARVWDMRTR 260 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 + +GH+ A L +GS D +++WD+ + + H + L Sbjct: 261 SNIHVLSGHKGTVADLKCQEADPQIITGSLDATVRLWDLAAGKTMGVLTHHKKGVRNLAI 320 Query: 549 TP 554 P Sbjct: 321 HP 322 Score = 46.2 bits (108), Expect = 7e-05 Identities = 25/77 (32%), Positives = 38/77 (49%) Frame = +3 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 K++R +GH SL P ++FASG+ D +KIW++ T GH + L Sbjct: 135 KLMRVISGHLGWVRSLAVEPNNEWFASGAGDRTIKIWNLATGALRLTLTGHISTVRGLAV 194 Query: 549 TPDGRWIVSGGADSSVK 599 +P ++ S G D VK Sbjct: 195 SPRHPYLFSCGEDKMVK 211
>PRP46_YARLI (Q6C709) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 472 Score = 75.9 bits (185), Expect = 8e-14 Identities = 39/135 (28%), Positives = 64/135 (47%) Frame = +3 Query: 195 TGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKV 374 TG D+ + +W + L+L+G V +L + +G +K WD+E KV Sbjct: 180 TGSADKTIKIWDLATGKLRLTLTGHIMGVRALGVSPRHPYMFSGGEDKMVKCWDLETNKV 239 Query: 375 VRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTP 554 VR + GH S SLD HP D S D ++WD+R + + GH I+ ++F Sbjct: 240 VRHYHGHLSAVYSLDIHPTLDVLVSAGRDAVARVWDIRTRDPVVVLSGHKSTINRVKFQA 299 Query: 555 DGRWIVSGGADSSVK 599 +++ AD +V+ Sbjct: 300 SEPQVITASADETVR 314 Score = 60.8 bits (146), Expect = 3e-09 Identities = 36/140 (25%), Positives = 64/140 (45%) Frame = +3 Query: 177 TSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWD 356 T L++ G D +W + V+ LSG S + + F +SE + +A T+++W+ Sbjct: 258 TLDVLVSAGRDAVARVWDIRTRDPVVVLSGHKSTINRVKFQASEPQVITASADETVRLWN 317 Query: 357 IEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRID 536 ++ K + T T H+ + L HP +F S +S + K W + + Y I+ Sbjct: 318 LQAGKTMTTLTHHKKSVRGLTLHP-EEFTFSTASANSSKQWKCPEGDLVLNYDDQNAIIN 376 Query: 537 VLRFTPDGRWIVSGGADSSV 596 L D + SGG + S+ Sbjct: 377 TLSVNQD-NVMFSGGDNGSI 395 Score = 60.8 bits (146), Expect = 3e-09 Identities = 33/111 (29%), Positives = 49/111 (44%) Frame = +3 Query: 258 LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGD 437 ++G V S+ + G+A TIKIWD+ K+ T TGH +L P Sbjct: 159 ITGHQGWVRSVCVEPENQWFATGSADKTIKIWDLATGKLRLTLTGHIMGVRALGVSPRHP 218 Query: 438 FFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADS 590 + SG D +K WD+ + + Y GH + L P +VS G D+ Sbjct: 219 YMFSGGEDKMVKCWDLETNKVVRHYHGHLSAVYSLDIHPTLDVLVSAGRDA 269 Score = 50.8 bits (120), Expect = 3e-06 Identities = 26/77 (33%), Positives = 40/77 (51%) Frame = +3 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 ++ R TGH+ S+ P +FA+GS+D +KIWD+ + T GH + L Sbjct: 154 EIYRVITGHQGWVRSVCVEPENQWFATGSADKTIKIWDLATGKLRLTLTGHIMGVRALGV 213 Query: 549 TPDGRWIVSGGADSSVK 599 +P ++ SGG D VK Sbjct: 214 SPRHPYMFSGGEDKMVK 230 Score = 48.1 bits (113), Expect = 2e-05 Identities = 32/136 (23%), Positives = 59/136 (43%), Gaps = 1/136 (0%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSS-EVMIGAGAASGTIKIWDIEE 365 + +GGED+ V W + V G S V SL + +V++ AG ++WDI Sbjct: 220 MFSGGEDKMVKCWDLETNKVVRHYHGHLSAVYSLDIHPTLDVLVSAG-RDAVARVWDIRT 278 Query: 366 AKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLR 545 V +GH+S + + S+D +++W+++ + + T H + L Sbjct: 279 RDPVVVLSGHKSTINRVKFQASEPQVITASADETVRLWNLQAGKTMTTLTHHKKSVRGLT 338 Query: 546 FTPDGRWIVSGGADSS 593 P+ + A+SS Sbjct: 339 LHPEEFTFSTASANSS 354
>GBLP_DICDI (P46800) Guanine nucleotide-binding protein beta subunit-like| protein Length = 329 Score = 75.9 bits (185), Expect = 8e-14 Identities = 44/137 (32%), Positives = 68/137 (49%), Gaps = 4/137 (2%) Frame = +3 Query: 192 ITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWD-IEEA 368 ++G D + LW + K + G T V S++F S I +G+ TIK+W+ + E Sbjct: 86 LSGSWDNTLRLWDITKGVSTRLFKGHTQDVMSVAFSSDNRQIISGSRDATIKVWNTLGEC 145 Query: 369 KVVRTFTG---HRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDV 539 K T G H+ + + P SGS D +KIWD++ +C HT HTG ++ Sbjct: 146 KF--TLEGPEAHQDWVSCIRFSPNTPTIVSGSWDNKVKIWDIKSFKCNHTLTDHTGYVNT 203 Query: 540 LRFTPDGRWIVSGGADS 590 + +PDG SGG D+ Sbjct: 204 VTISPDGSLCASGGKDT 220 Score = 61.2 bits (147), Expect = 2e-09 Identities = 45/165 (27%), Positives = 70/165 (42%), Gaps = 9/165 (5%) Frame = +3 Query: 132 VAHASDVTCAKFGKRTSRTLITGGEDQKVNLW------AVGKPTAVLSLSGLTSPVESLS 293 V H VT T+I+ D+ V +W A A SL G + V+ + Sbjct: 18 VGHNGFVTSIAVSPENPDTIISSSRDKTVMVWQLTPTDATSPGKAHRSLKGHSHFVQDVV 77 Query: 294 FDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMK 473 +G+ T+++WDI + R F GH + S+ SGS D +K Sbjct: 78 ISHDGQFALSGSWDNTLRLWDITKGVSTRLFKGHTQDVMSVAFSSDNRQIISGSRDATIK 137 Query: 474 IWDMRKKRCIHTYQG---HTGRIDVLRFTPDGRWIVSGGADSSVK 599 +W+ + C T +G H + +RF+P+ IVSG D+ VK Sbjct: 138 VWNTLGE-CKFTLEGPEAHQDWVSCIRFSPNTPTIVSGSWDNKVK 181 Score = 58.2 bits (139), Expect = 2e-08 Identities = 40/160 (25%), Positives = 70/160 (43%), Gaps = 4/160 (2%) Frame = +3 Query: 129 FVAHASDVTCAKFGKRTSRTLITGGEDQKVNLW-AVGKPTAVLSLSGLTSP---VESLSF 296 F H DV F +R +I+G D + +W +G+ +L G + V + F Sbjct: 108 FKGHTQDVMSVAFSS-DNRQIISGSRDATIKVWNTLGE--CKFTLEGPEAHQDWVSCIRF 164 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 + I +G+ +KIWDI+ K T T H ++ P G ASG DT + Sbjct: 165 SPNTPTIVSGSWDNKVKIWDIKSFKCNHTLTDHTGYVNTVTISPDGSLCASGGKDTFACL 224 Query: 477 WDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 W++ + ++ + I+ L F+P+ W+ + D + Sbjct: 225 WELSSGKPLYKLEAR-NTINALAFSPNKYWLSAATDDKII 263
>LIS1_DROME (Q7KNS3) Lissencephaly-1 homolog (Lissencephaly1) (Dlis1) (DLis-1)| Length = 411 Score = 75.9 bits (185), Expect = 8e-14 Identities = 36/138 (26%), Positives = 73/138 (52%), Gaps = 1/138 (0%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 +++ ED + +W SL G T V+ ++FD+ ++ + +A +IK+WD +++ Sbjct: 123 MVSASEDATIRIWDFETGEYERSLKGHTDSVQDVAFDAQGKLLASCSADLSIKLWDFQQS 182 Query: 369 -KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLR 545 + ++T GH N +S+ P GD+ S S D +K+W++ C+ TY GH + ++R Sbjct: 183 YECIKTMHGHDHNVSSVAFVPAGDYVLSASRDRTIKMWEVATGYCVKTYTGHREWVRMVR 242 Query: 546 FTPDGRWIVSGGADSSVK 599 +G + D +++ Sbjct: 243 VHIEGSIFATCSNDQTIR 260 Score = 70.9 bits (172), Expect = 3e-12 Identities = 44/160 (27%), Positives = 70/160 (43%), Gaps = 11/160 (6%) Frame = +3 Query: 153 TCAKFGKRTSRTLITGGEDQKVNL-----------WAVGKPTAVLSLSGLTSPVESLSFD 299 TC+ +T R +T +D KV L WA P A S + ++ Sbjct: 252 TCSN--DQTIRVWLTNSKDCKVELRDHEHTVECIAWA---PEAAASAINEAAGADNKKGH 306 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 + +G+ TI+IWD+ + T +GH + L HP G + S S D +++W Sbjct: 307 HQGPFLASGSRDKTIRIWDVSVGLCLLTLSGHDNWVRGLAFHPGGKYLVSASDDKTIRVW 366 Query: 480 DMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 D+R KRC+ T H + F +++SG D +VK Sbjct: 367 DLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVK 406 Score = 67.0 bits (162), Expect = 4e-11 Identities = 33/124 (26%), Positives = 61/124 (49%), Gaps = 1/124 (0%) Frame = +3 Query: 231 VGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCA 410 + +P SL+G + + + F ++ + + TI+IWD E + R+ GH + Sbjct: 95 IPRPPEKFSLTGHRASITRVIFHPIFALMVSASEDATIRIWDFETGEYERSLKGHTDSVQ 154 Query: 411 SLDSHPFGDFFASGSSDTNMKIWDMRKK-RCIHTYQGHTGRIDVLRFTPDGRWIVSGGAD 587 + G AS S+D ++K+WD ++ CI T GH + + F P G +++S D Sbjct: 155 DVAFDAQGKLLASCSADLSIKLWDFQQSYECIKTMHGHDHNVSSVAFVPAGDYVLSASRD 214 Query: 588 SSVK 599 ++K Sbjct: 215 RTIK 218 Score = 65.5 bits (158), Expect = 1e-10 Identities = 31/109 (28%), Positives = 54/109 (49%) Frame = +3 Query: 162 KFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGT 341 K G L +G D+ + +W V +L+LSG + V L+F + + + T Sbjct: 303 KKGHHQGPFLASGSRDKTIRIWDVSVGLCLLTLSGHDNWVRGLAFHPGGKYLVSASDDKT 362 Query: 342 IKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMR 488 I++WD+ + ++T H+ C S+D H + SGS D +K+W+ R Sbjct: 363 IRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVWECR 411 Score = 53.5 bits (127), Expect = 4e-07 Identities = 29/126 (23%), Positives = 59/126 (46%), Gaps = 1/126 (0%) Frame = +3 Query: 183 RTLITGGEDQKVNLWAVGKP-TAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDI 359 + L + D + LW + + ++ G V S++F + + + + TIK+W++ Sbjct: 163 KLLASCSADLSIKLWDFQQSYECIKTMHGHDHNVSSVAFVPAGDYVLSASRDRTIKMWEV 222 Query: 360 EEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDV 539 V+T+TGHR + H G FA+ S+D +++W K C + H ++ Sbjct: 223 ATGYCVKTYTGHREWVRMVRVHIEGSIFATCSNDQTIRVWLTNSKDCKVELRDHEHTVEC 282 Query: 540 LRFTPD 557 + + P+ Sbjct: 283 IAWAPE 288
>SCON2_NEUCR (Q01277) Sulfur controller 2 (SCON2)| Length = 650 Score = 75.9 bits (185), Expect = 8e-14 Identities = 46/162 (28%), Positives = 78/162 (48%) Frame = +3 Query: 114 YKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLS 293 YKL H + VTC + L TG D + +W + + +L G T+ + +L Sbjct: 285 YKLSVLKGHENGVTCLQLD---DNILATGSYDTTIKIWNIETEECIRTLVGHTAGIRALQ 341 Query: 294 FDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMK 473 FD S+++ +G+ TIK+W+ + + TF H + S+ H G ASGSSD +K Sbjct: 342 FDDSKLI--SGSLDHTIKVWNWHTGECLSTFAAHTDSVISV--HFDGHLLASGSSDKTVK 397 Query: 474 IWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 I+D K + +GH+ ++ R + S D+++K Sbjct: 398 IFDFNSKE-TYCLKGHSDWVNSTHVDIKSRTVFSASDDTTIK 438 Score = 45.8 bits (107), Expect = 9e-05 Identities = 25/92 (27%), Positives = 42/92 (45%) Frame = +3 Query: 324 GAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCI 503 G T+++WD + +RT GH SL SG++D +K W+ R +C Sbjct: 554 GGLDSTMRLWDSATGRCLRTLFGHLEGVWSLAGDTIR--VISGANDGMVKTWEPRSGKCD 611 Query: 504 HTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 TY GH G + + + + SG D +++ Sbjct: 612 ATYTGHCGPVTCVGLSDS--LMASGSEDGTIR 641 Score = 45.1 bits (105), Expect = 2e-04 Identities = 32/107 (29%), Positives = 47/107 (43%), Gaps = 2/107 (1%) Frame = +3 Query: 183 RTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIE 362 R +TGG D + LW + +L G V SL+ D+ V+ +GA G +K W+ Sbjct: 549 RYFMTGGLDSTMRLWDSATGRCLRTLFGHLEGVWSLAGDTIRVI--SGANDGMVKTWEPR 606 Query: 363 EAKVVRTFTGHRS--NCASLDSHPFGDFFASGSSDTNMKIWDMRKKR 497 K T+TGH C L ASGS D +++ + R Sbjct: 607 SGKCDATYTGHCGPVTCVGLSD----SLMASGSEDGTIRLHSFKPCR 649 Score = 36.6 bits (83), Expect = 0.057 Identities = 41/179 (22%), Positives = 66/179 (36%), Gaps = 39/179 (21%) Frame = +3 Query: 180 SRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSF------DSSEVMIGAG----- 326 SRT+ + +D + LW + + + G V+ + EV+ GA Sbjct: 425 SRTVFSASDDTTIKLWDLDTRQVIRTYEGHVGHVQQVLILPPEYEPDEEVLNGASQDNQD 484 Query: 327 ---AASGTIKIWDIEEAKVVRTFT-GHRSNCASL--DSHPFGD----------------- 437 +SG + A++ R + G S+ +L S P GD Sbjct: 485 AMSVSSGGSGSPSMSHAQIERAGSPGSHSSSHNLLPSSLPSGDEDVRHLYGSAFVADESR 544 Query: 438 -----FFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 +F +G D+ M++WD RC+ T GH V D ++SG D VK Sbjct: 545 PLPPRYFMTGGLDSTMRLWDSATGRCLRTLFGHLE--GVWSLAGDTIRVISGANDGMVK 601
>SCONB_EMENI (Q00659) Sulfur metabolite repression control protein| Length = 678 Score = 75.5 bits (184), Expect = 1e-13 Identities = 45/160 (28%), Positives = 75/160 (46%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 ++ F H + V C +F L TG D + +W + +L G S + L FD Sbjct: 342 IKTFKGHTNGVMCLQF---EDNILATGSYDTTIKIWDTETGEELRTLRGHESGIRCLQFD 398 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 ++++ +G+ TIK+W+ + + T+TGHR L H ASGS D +KIW Sbjct: 399 DTKLI--SGSMDRTIKVWNWRTGECISTYTGHRGGVIGL--HFDASILASGSVDKTVKIW 454 Query: 480 DMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 + K + +GHT ++ +R R + S D +V+ Sbjct: 455 NFEDKSTF-SLRGHTDWVNAVRVDTSSRTVFSASDDCTVR 493 Score = 71.2 bits (173), Expect = 2e-12 Identities = 45/126 (35%), Positives = 63/126 (50%), Gaps = 1/126 (0%) Frame = +3 Query: 225 WAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSN 404 W G+ ++ + G T+ V L F+ + ++ G+ TIKIWD E + +RT GH S Sbjct: 335 WKYGR-CSIKTFKGHTNGVMCLQFEDN--ILATGSYDTTIKIWDTETGEELRTLRGHESG 391 Query: 405 CASLDSHPFGDF-FASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGG 581 L F D SGS D +K+W+ R CI TY GH G + L F D + SG Sbjct: 392 IRCLQ---FDDTKLISGSMDRTIKVWNWRTGECISTYTGHRGGVIGLHF--DASILASGS 446 Query: 582 ADSSVK 599 D +VK Sbjct: 447 VDKTVK 452 Score = 66.2 bits (160), Expect = 7e-11 Identities = 41/146 (28%), Positives = 71/146 (48%), Gaps = 2/146 (1%) Frame = +3 Query: 102 TKRAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPV 281 T+ +L+ H S + C +F LI+G D+ + +W + + +G V Sbjct: 376 TETGEELRTLRGHESGIRCLQFD---DTKLISGSMDRTIKVWNWRTGECISTYTGHRGGV 432 Query: 282 ESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRS--NCASLDSHPFGDFFASGS 455 L FD+S ++ +G+ T+KIW+ E+ K + GH N +D+ F S S Sbjct: 433 IGLHFDAS--ILASGSVDKTVKIWNFED-KSTFSLRGHTDWVNAVRVDTSSRTVF--SAS 487 Query: 456 SDTNMKIWDMRKKRCIHTYQGHTGRI 533 D +++WD+ K CI T+ GH G++ Sbjct: 488 DDCTVRLWDLDTKTCIRTFHGHVGQV 513 Score = 49.7 bits (117), Expect = 6e-06 Identities = 28/91 (30%), Positives = 45/91 (49%) Frame = +3 Query: 327 AASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIH 506 A TI++W+ + +RTF GH +L + SG+ D +KIWD R +C Sbjct: 586 ALDSTIRLWETTTGRCLRTFFGHLEGVWALGADTLR--IVSGAEDRMIKIWDPRTGKCER 643 Query: 507 TYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 T+ GH+G + + D R+ +G D V+ Sbjct: 644 TFTGHSGPVTCIGL-GDSRF-ATGSEDCEVR 672 Score = 46.2 bits (108), Expect = 7e-05 Identities = 42/194 (21%), Positives = 70/194 (36%), Gaps = 57/194 (29%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L +G D+ V +W + + SL G T V ++ D+S + + + T+++WD++ Sbjct: 442 LASGSVDKTVKIWNF-EDKSTFSLRGHTDWVNAVRVDTSSRTVFSASDDCTVRLWDLDTK 500 Query: 369 KVVRTFTGH----------------------------------------------RSNCA 410 +RTF GH N A Sbjct: 501 TCIRTFHGHVGQVQQVVPLPREFEFEEHDAECENDDLSTTSGDANPPSIQASMGLEPNAA 560 Query: 411 SLDSHPFGDFFASGSS-----------DTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPD 557 S FG F +G + D+ +++W+ RC+ T+ GH + L D Sbjct: 561 YSQSSAFGTSFDNGRAAPPRYMVTSALDSTIRLWETTTGRCLRTFFGHLEGVWAL--GAD 618 Query: 558 GRWIVSGGADSSVK 599 IVSG D +K Sbjct: 619 TLRIVSGAEDRMIK 632 Score = 45.8 bits (107), Expect = 9e-05 Identities = 32/105 (30%), Positives = 48/105 (45%), Gaps = 3/105 (2%) Frame = +3 Query: 183 RTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIE 362 R ++T D + LW + + G V +L D+ ++ +GA IKIWD Sbjct: 580 RYMVTSALDSTIRLWETTTGRCLRTFFGHLEGVWALGADTLRIV--SGAEDRMIKIWDPR 637 Query: 363 EAKVVRTFTGHRS--NCASL-DSHPFGDFFASGSSDTNMKIWDMR 488 K RTFTGH C L DS FA+GS D ++++ + Sbjct: 638 TGKCERTFTGHSGPVTCIGLGDSR-----FATGSEDCEVRMYSFQ 677
>MET30_YEAST (P39014) F-box protein MET30 (Methionine requiring protein 30) (E3| ubiquitin ligase complex SCF(Met30) subunit MET30) Length = 640 Score = 75.5 bits (184), Expect = 1e-13 Identities = 43/161 (26%), Positives = 81/161 (50%) Frame = +3 Query: 117 KLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSF 296 ++QEF H V +F R L TG D + +W + + LSG + V++L F Sbjct: 294 RIQEFKGHMDGVLTLQFNYRL---LFTGSYDSTIGIWDLFTGKLIRRLSGHSDGVKTLYF 350 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 D +++ G+ TI++W+ + + T+ GH + S+DS + SGS+D +K+ Sbjct: 351 DDRKLI--TGSLDKTIRVWNYITGECISTYRGHSDSVLSVDS--YQKVIVSGSADKTVKV 406 Query: 477 WDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 W + + C +T +GHT ++ ++ P S D++++ Sbjct: 407 WHVESRTC-YTLRGHTEWVNCVKLHPKSFSCFSCSDDTTIR 446 Score = 68.9 bits (167), Expect = 1e-11 Identities = 39/119 (32%), Positives = 63/119 (52%), Gaps = 2/119 (1%) Frame = +3 Query: 183 RTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIE 362 R LITG D+ + +W + + G + V LS DS + +I +G+A T+K+W +E Sbjct: 353 RKLITGSLDKTIRVWNYITGECISTYRGHSDSV--LSVDSYQKVIVSGSADKTVKVWHVE 410 Query: 363 EAKVVRTFTGHRS--NCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRI 533 ++ T GH NC L F F S S DT +++WD+R C+ ++GH G++ Sbjct: 411 -SRTCYTLRGHTEWVNCVKLHPKSFSCF--SCSDDTTIRMWDIRTNSCLKVFRGHVGQV 466 Score = 51.6 bits (122), Expect = 2e-06 Identities = 22/60 (36%), Positives = 36/60 (60%) Frame = +3 Query: 339 TIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQG 518 TIK+WD++ K +RT GH + + F SGS D ++K+WD++ +C+HT+ G Sbjct: 533 TIKLWDVKTGKCIRTQFGHVEGVWDIAADNFR--IISGSHDGSIKVWDLQSGKCMHTFNG 590 Score = 41.6 bits (96), Expect = 0.002 Identities = 20/70 (28%), Positives = 37/70 (52%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L++ G D + LW V + + G V ++ D+ ++ +G+ G+IK+WD++ Sbjct: 525 LLSCGLDNTIKLWDVKTGKCIRTQFGHVEGVWDIAADNFRII--SGSHDGSIKVWDLQSG 582 Query: 369 KVVRTFTGHR 398 K + TF G R Sbjct: 583 KCMHTFNGRR 592 Score = 41.2 bits (95), Expect = 0.002 Identities = 37/186 (19%), Positives = 62/186 (33%), Gaps = 47/186 (25%) Frame = +3 Query: 183 RTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIE 362 + +++G D+ V +W V T +L G T V + + + TI++WDI Sbjct: 393 KVIVSGSADKTVKVWHVESRTCY-TLRGHTEWVNCVKLHPKSFSCFSCSDDTTIRMWDIR 451 Query: 363 EAKVVRTFTGHRSNCASL------------------------------------------ 416 ++ F GH + Sbjct: 452 TNSCLKVFRGHVGQVQKIIPLTIKDVENLATDNTSDGSSPQDDPTMTDGADESDTPSNEQ 511 Query: 417 -----DSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGG 581 ++ P+ S D +K+WD++ +CI T GH V D I+SG Sbjct: 512 ETVLDENIPYPTHLLSCGLDNTIKLWDVKTGKCIRTQFGHVE--GVWDIAADNFRIISGS 569 Query: 582 ADSSVK 599 D S+K Sbjct: 570 HDGSIK 575
>GBB2_CAEEL (Q20636) Guanine nucleotide-binding protein beta subunit 2| Length = 356 Score = 75.5 bits (184), Expect = 1e-13 Identities = 45/165 (27%), Positives = 82/165 (49%), Gaps = 5/165 (3%) Frame = +3 Query: 117 KLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSF 296 K ++ H S ++C F R+ ++TG D +W V + + G T V ++ Sbjct: 148 KKRQVATHTSYMSCCTF-LRSDNLILTGSGDSTCAIWDVESGQLIQNFHGHTGDVFAIDV 206 Query: 297 ---DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTN 467 D+ I AGA ++ +WDI + V++F GH ++ ++ HP GD FA+GS D Sbjct: 207 PKCDTGNTFISAGADKHSL-VWDIRSGQCVQSFEGHEADINTVRFHPNGDAFATGSDDAT 265 Query: 468 MKIWDMRKKR--CIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 +++D+R R C++ + ++ + F+ GR + +G D V Sbjct: 266 CRLFDLRADRQVCVYEKESILFPVNGVDFSLSGRILFAGYGDYRV 310 Score = 72.0 bits (175), Expect = 1e-12 Identities = 37/147 (25%), Positives = 77/147 (52%), Gaps = 6/147 (4%) Frame = +3 Query: 177 TSRTLITGGEDQKVNLWAVGKPTAVLS----LSGLTSPVESLSFDSSEVMIGAGAASGTI 344 +S+ + GG D K ++ + ++ ++ TS + +F S+ +I G+ T Sbjct: 121 SSQMIACGGLDNKCSVVPLSFEDDIIQKKRQVATHTSYMSCCTFLRSDNLILTGSGDSTC 180 Query: 345 KIWDIEEAKVVRTFTGHRSNCASLD--SHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQG 518 IWD+E ++++ F GH + ++D G+ F S +D + +WD+R +C+ +++G Sbjct: 181 AIWDVESGQLIQNFHGHTGDVFAIDVPKCDTGNTFISAGADKHSLVWDIRSGQCVQSFEG 240 Query: 519 HTGRIDVLRFTPDGRWIVSGGADSSVK 599 H I+ +RF P+G +G D++ + Sbjct: 241 HEADINTVRFHPNGDAFATGSDDATCR 267 Score = 42.7 bits (99), Expect = 8e-04 Identities = 28/122 (22%), Positives = 48/122 (39%), Gaps = 2/122 (1%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAV--GKPTAVLSLSGLTSPVESLS 293 +Q F H +D+ +F TG +D L+ + + V + PV + Sbjct: 235 VQSFEGHEADINTVRFHPNGD-AFATGSDDATCRLFDLRADRQVCVYEKESILFPVNGVD 293 Query: 294 FDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMK 473 F S ++ AG + +WD + GH + + L + P G S S D ++ Sbjct: 294 FSLSGRILFAGYGDYRVGVWDSLKCARHSVLYGHENRISCLRTSPDGTAVCSASWDCTIR 353 Query: 474 IW 479 IW Sbjct: 354 IW 355
>Y163_SYNY3 (Q55563) Hypothetical WD-repeat protein sll0163| Length = 1693 Score = 75.5 bits (184), Expect = 1e-13 Identities = 45/155 (29%), Positives = 75/155 (48%), Gaps = 1/155 (0%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWA-VGKPTAVLSLSGLTSPVESLSFDSSEVM 314 H V A+F SR ++T D +W +G+P +L+L+G S V F + Sbjct: 1505 HEGPVYFAQFSA-DSRYILTASVDNTARIWDFLGRP--LLTLAGHQSIVYQARFSPEGNL 1561 Query: 315 IGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKK 494 I +A T ++WD K V GH+ ++D P G + S+D ++WD+ + Sbjct: 1562 IATVSADHTARLWD-RSGKTVAVLYGHQGLVGTVDWSPDGQMLVTASNDGTARLWDLSGR 1620 Query: 495 RCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 + T +GH + F+PDGRW+++ AD + K Sbjct: 1621 ELL-TLEGHGNWVRSAEFSPDGRWVLTSSADGTAK 1654 Score = 60.5 bits (145), Expect = 4e-09 Identities = 40/154 (25%), Positives = 68/154 (44%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMI 317 H ++ A+F + ++T D LW + T + L G V F + + Sbjct: 1259 HDHNIHGARFSL-DGQKIVTYSTDNTARLWTK-EGTLLTILRGHQKEVYDADFSADGRFV 1316 Query: 318 GAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKR 497 +A T + WDI + + T TGH + +P GD + S D ++W + Sbjct: 1317 FTVSADQTARQWDISQKDTI-TLTGHSHWVRNAHFNPKGDRLLTVSRDKTARLWTTEGE- 1374 Query: 498 CIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 C+ H G + +F+PDG+WIV+G AD + + Sbjct: 1375 CVAVLADHQGWVREGQFSPDGQWIVTGSADKTAQ 1408 Score = 56.6 bits (135), Expect = 5e-08 Identities = 42/154 (27%), Positives = 70/154 (45%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMI 317 HA V A+F + L+T D LW + + + G TS V + F I Sbjct: 1136 HADWVRNAEFNCH-GQILLTASRDGTARLWDL-EGREIGLCQGHTSWVRNAQFSPDGQWI 1193 Query: 318 GAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKR 497 +A GT ++WD+ ++ GH++ + P G + SSD ++W R + Sbjct: 1194 VTCSADGTARLWDLS-SQCFAVLKGHQNWVNNALWSPDGQHIITSSSDGTARVWS-RHGK 1251 Query: 498 CIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 C+ T +GH I RF+ DG+ IV+ D++ + Sbjct: 1252 CLGTLRGHDHNIHGARFSLDGQKIVTYSTDNTAR 1285 Score = 53.5 bits (127), Expect = 4e-07 Identities = 35/135 (25%), Positives = 57/135 (42%) Frame = +3 Query: 195 TGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKV 374 T D V LW V +L G V S+ F + T +IW+ ++ Sbjct: 1072 TASADHTVKLWQ-RHGEEVATLRGHEDWVRSVHFSPHHQFLVTSGQDNTARIWNFAGEQL 1130 Query: 375 VRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTP 554 GH + + + G + S D ++WD+ + I QGHT + +F+P Sbjct: 1131 TLC-QGHADWVRNAEFNCHGQILLTASRDGTARLWDLEGRE-IGLCQGHTSWVRNAQFSP 1188 Query: 555 DGRWIVSGGADSSVK 599 DG+WIV+ AD + + Sbjct: 1189 DGQWIVTCSADGTAR 1203 Score = 51.6 bits (122), Expect = 2e-06 Identities = 38/170 (22%), Positives = 74/170 (43%) Frame = +3 Query: 90 SRMATKRAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGL 269 +R+ TK L H +V A F R + T DQ W + + + +L+G Sbjct: 1284 ARLWTKEGTLLTILRGHQKEVYDADFSA-DGRFVFTVSADQTARQWDISQKDTI-TLTGH 1341 Query: 270 TSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFAS 449 + V + F+ + + T ++W E + V H+ P G + + Sbjct: 1342 SHWVRNAHFNPKGDRLLTVSRDKTARLWTTE-GECVAVLADHQGWVREGQFSPDGQWIVT 1400 Query: 450 GSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 GS+D ++W++ K+ + +GH + +RF+PD ++IV+ D + + Sbjct: 1401 GSADKTAQLWNVLGKK-LTVLRGHQDAVLNVRFSPDSQYIVTASKDGTAR 1449 Score = 48.5 bits (114), Expect = 1e-05 Identities = 24/105 (22%), Positives = 53/105 (50%) Frame = +3 Query: 285 SLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDT 464 S S +++ ++ +G +W +++ GH+ +LD G +FA+ S+D Sbjct: 1019 SPSMENTPPLVLTATTNGIAYLWSFH-GELINVLRGHQEAITALDWSADGQYFATASADH 1077 Query: 465 NMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 +K+W R + T +GH + + F+P +++V+ G D++ + Sbjct: 1078 TVKLW-QRHGEEVATLRGHEDWVRSVHFSPHHQFLVTSGQDNTAR 1121 Score = 40.8 bits (94), Expect = 0.003 Identities = 34/152 (22%), Positives = 63/152 (41%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMI 317 H+ V A F + R L+T D+ LW + V L+ V F I Sbjct: 1341 HSHWVRNAHFNPKGDR-LLTVSRDKTARLWTT-EGECVAVLADHQGWVREGQFSPDGQWI 1398 Query: 318 GAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKR 497 G+A T ++W++ K+ GH+ ++ P + + S D ++W+ R Sbjct: 1399 VTGSADKTAQLWNVLGKKLT-VLRGHQDAVLNVRFSPDSQYIVTASKDGTARVWN-NTGR 1456 Query: 498 CIHTYQGHTGRIDVLRFTPDGRWIVSGGADSS 593 + + + I F+ DG++IV+ D++ Sbjct: 1457 ELAVLRHYEKNIFAAEFSADGQFIVTASDDNT 1488 Score = 40.0 bits (92), Expect = 0.005 Identities = 32/124 (25%), Positives = 53/124 (42%), Gaps = 1/124 (0%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLW-AVGKPTAVLSLSGLTSPVESLSF 296 L H S V A+F + T D LW GK AVL G V ++ + Sbjct: 1540 LLTLAGHQSIVYQARFSPE-GNLIATVSADHTARLWDRSGKTVAVLY--GHQGLVGTVDW 1596 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 M+ + GT ++WD+ +++ T GH + S + P G + + S+D K+ Sbjct: 1597 SPDGQMLVTASNDGTARLWDLSGRELL-TLEGHGNWVRSAEFSPDGRWVLTSSADGTAKL 1655 Query: 477 WDMR 488 W ++ Sbjct: 1656 WPVK 1659
>TUP12_SCHPO (Q9UUG8) Transcriptional repressor tup12| Length = 586 Score = 75.1 bits (183), Expect = 1e-13 Identities = 51/180 (28%), Positives = 80/180 (44%), Gaps = 12/180 (6%) Frame = +3 Query: 96 MATKRAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTS 275 +A KR Y+L H ++ F K +TL++G D+ V LW V L L Sbjct: 363 IAQKRVYRL--LTGHEQEIYSLDFSK-DGKTLVSGSGDRTVCLWDVEAGEQKLILH-TDD 418 Query: 276 PVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGS 455 V ++ F I AG+ I+IW +V GH + S+ P G + SGS Sbjct: 419 GVTTVMFSPDGQFIAAGSLDKVIRIWT-SSGTLVEQLHGHEESVYSVAFSPDGKYLVSGS 477 Query: 456 SDTNMKIWDMRKKR------------CIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 D +K+W+++ C T+ GH I + +PDG+WI+SG D +++ Sbjct: 478 LDNTIKLWELQCVSNVAPSMYKEGGICKQTFTGHKDFILSVTVSPDGKWIISGSKDRTIQ 537 Score = 70.1 bits (170), Expect = 5e-12 Identities = 39/140 (27%), Positives = 70/140 (50%), Gaps = 3/140 (2%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L TG EDQ++ +W + + L+G + SL F + +G+ T+ +WD+E Sbjct: 349 LATGVEDQQIRIWDIAQKRVYRLLTGHEQEIYSLDFSKDGKTLVSGSGDRTVCLWDVEAG 408 Query: 369 K---VVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDV 539 + ++ T G ++ P G F A+GS D ++IW + GH + Sbjct: 409 EQKLILHTDDG----VTTVMFSPDGQFIAAGSLDKVIRIW-TSSGTLVEQLHGHEESVYS 463 Query: 540 LRFTPDGRWIVSGGADSSVK 599 + F+PDG+++VSG D+++K Sbjct: 464 VAFSPDGKYLVSGSLDNTIK 483 Score = 65.5 bits (158), Expect = 1e-10 Identities = 35/110 (31%), Positives = 54/110 (49%), Gaps = 3/110 (2%) Frame = +3 Query: 279 VESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSS 458 V S++F + G I+IWDI + +V R TGH SLD G SGS Sbjct: 337 VRSVAFSPDGKYLATGVEDQQIRIWDIAQKRVYRLLTGHEQEIYSLDFSKDGKTLVSGSG 396 Query: 459 DTNMKIWDM---RKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 D + +WD+ +K +HT G + + F+PDG++I +G D ++ Sbjct: 397 DRTVCLWDVEAGEQKLILHTDDG----VTTVMFSPDGQFIAAGSLDKVIR 442 Score = 63.5 bits (153), Expect = 4e-10 Identities = 40/167 (23%), Positives = 67/167 (40%), Gaps = 12/167 (7%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 Q+ + H D + + G D+ + +W T V L G V S++F Sbjct: 410 QKLILHTDDGVTTVMFSPDGQFIAAGSLDKVIRIWT-SSGTLVEQLHGHEESVYSVAFSP 468 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVV------------RTFTGHRSNCASLDSHPFGDFFA 446 + +G+ TIK+W+++ V +TFTGH+ S+ P G + Sbjct: 469 DGKYLVSGSLDNTIKLWELQCVSNVAPSMYKEGGICKQTFTGHKDFILSVTVSPDGKWII 528 Query: 447 SGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGAD 587 SGS D ++ W T QGH + + +P+G +G D Sbjct: 529 SGSKDRTIQFWSPDSPHSQLTLQGHNNSVISVAVSPNGHCFATGSGD 575 Score = 40.4 bits (93), Expect = 0.004 Identities = 31/141 (21%), Positives = 55/141 (39%), Gaps = 12/141 (8%) Frame = +3 Query: 93 RMATKRAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVL------ 254 R+ T +++ H V F + L++G D + LW + + V Sbjct: 442 RIWTSSGTLVEQLHGHEESVYSVAFSP-DGKYLVSGSLDNTIKLWELQCVSNVAPSMYKE 500 Query: 255 ------SLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASL 416 + +G + S++ I +G+ TI+ W + T GH ++ S+ Sbjct: 501 GGICKQTFTGHKDFILSVTVSPDGKWIISGSKDRTIQFWSPDSPHSQLTLQGHNNSVISV 560 Query: 417 DSHPFGDFFASGSSDTNMKIW 479 P G FA+GS D +IW Sbjct: 561 AVSPNGHCFATGSGDLRARIW 581
>GBB5_HUMAN (O14775) Guanine nucleotide-binding protein beta subunit 5| (Transducin beta chain 5) (Gbeta5) Length = 395 Score = 75.1 bits (183), Expect = 1e-13 Identities = 34/112 (30%), Positives = 62/112 (55%), Gaps = 2/112 (1%) Frame = +3 Query: 270 TSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPF--GDFF 443 T+ + + SF +S++ I + GT +WD+E +++++F GH ++ LD P G+ F Sbjct: 195 TNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTF 254 Query: 444 ASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 SG D +WDMR +C+ ++ H I+ +R+ P G SG D++ + Sbjct: 255 VSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATCR 306 Score = 69.3 bits (168), Expect = 8e-12 Identities = 41/163 (25%), Positives = 73/163 (44%), Gaps = 3/163 (1%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFG-KRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSF 296 LQ F H +DV C T T ++GG D+K +W + V + S + S+ + Sbjct: 230 LQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRY 289 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRS--NCASLDSHPFGDFFASGSSDTNM 470 S +G+ T +++D+ + V ++ +S+D G +G +D + Sbjct: 290 YPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTI 349 Query: 471 KIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 +WD+ K + GH R+ LR +PDG SG D +++ Sbjct: 350 NVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLR 392 Score = 52.4 bits (124), Expect = 1e-06 Identities = 31/122 (25%), Positives = 55/122 (45%), Gaps = 2/122 (1%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAV--GKPTAVLSLSGLTSPVESLS 293 +Q F H SD+ ++ + +G +D L+ + + A+ S + S+ Sbjct: 274 VQAFETHESDINSVRYYP-SGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVD 332 Query: 294 FDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMK 473 F S ++ AG TI +WD+ + V GH + ++L P G F SGS D ++ Sbjct: 333 FSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLR 392 Query: 474 IW 479 +W Sbjct: 393 VW 394
>WDR5_MOUSE (P61965) WD-repeat protein 5 (BMP2-induced 3-kb gene protein)| (WD-repeat protein BIG-3) Length = 334 Score = 75.1 bits (183), Expect = 1e-13 Identities = 37/150 (24%), Positives = 70/150 (46%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMI 317 H V+ KF L + D+ + +W ++SG + +++ S ++ Sbjct: 44 HTKAVSSVKFSPN-GEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLL 102 Query: 318 GAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKR 497 + + T+KIWD+ K ++T GH + + +P + SGS D +++IWD++ + Sbjct: 103 VSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGK 162 Query: 498 CIHTYQGHTGRIDVLRFTPDGRWIVSGGAD 587 C+ T H+ + + F DG IVS D Sbjct: 163 CLKTLPAHSDPVSAVHFNRDGSLIVSSSYD 192 Score = 73.9 bits (180), Expect = 3e-13 Identities = 43/163 (26%), Positives = 76/163 (46%), Gaps = 4/163 (2%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 L+ H++ V C F + S +++G D+ V +W V + +L + PV ++ F+ Sbjct: 122 LKTLKGHSNYVFCCNFNPQ-SNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFN 180 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCAS-LDSHPFGDFFASGSSDTNMKI 476 +I + + G +IWD + ++T + S + P G + + + D +K+ Sbjct: 181 RDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKL 240 Query: 477 WDMRKKRCIHTYQGHTGR---IDVLRFTPDGRWIVSGGADSSV 596 WD K +C+ TY GH I G+WIVSG D+ V Sbjct: 241 WDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLV 283 Score = 73.2 bits (178), Expect = 5e-13 Identities = 39/128 (30%), Positives = 61/128 (47%), Gaps = 7/128 (5%) Frame = +3 Query: 237 KPTAV-------LSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGH 395 KPT V +L+G T V S+ F + + + +A IKIW + K +T +GH Sbjct: 27 KPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGH 86 Query: 396 RSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVS 575 + + + + S S D +KIWD+ +C+ T +GH+ + F P IVS Sbjct: 87 KLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVS 146 Query: 576 GGADSSVK 599 G D SV+ Sbjct: 147 GSFDESVR 154 Score = 67.8 bits (164), Expect = 2e-11 Identities = 32/141 (22%), Positives = 73/141 (51%), Gaps = 1/141 (0%) Frame = +3 Query: 180 SRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDI 359 S L++ +D+ + +W V + +L G ++ V +F+ +I +G+ +++IWD+ Sbjct: 99 SNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDV 158 Query: 360 EEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHT-YQGHTGRID 536 + K ++T H +++ + G S S D +IWD +C+ T + Sbjct: 159 KTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVS 218 Query: 537 VLRFTPDGRWIVSGGADSSVK 599 ++F+P+G++I++ D+++K Sbjct: 219 FVKFSPNGKYILAATLDNTLK 239 Score = 59.3 bits (142), Expect = 8e-09 Identities = 37/139 (26%), Positives = 63/139 (45%), Gaps = 4/139 (2%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSL-SGLTSPVESLSF 296 L+ AH+ V+ F R +++ D +W + +L PV + F Sbjct: 164 LKTLPAHSDPVSAVHFN-RDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKF 222 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSN--CASLD-SHPFGDFFASGSSDTN 467 + I A T+K+WD + K ++T+TGH++ C + S G + SGS D Sbjct: 223 SPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNL 282 Query: 468 MKIWDMRKKRCIHTYQGHT 524 + IW+++ K + QGHT Sbjct: 283 VYIWNLQTKEIVQKLQGHT 301 Score = 33.5 bits (75), Expect = 0.48 Identities = 21/96 (21%), Positives = 42/96 (43%), Gaps = 5/96 (5%) Frame = +3 Query: 207 DQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEV---MIGAGAASGTIKIWDIEEAKVV 377 D + LW K + + +G + + + S I +G+ + IW+++ ++V Sbjct: 235 DNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIV 294 Query: 378 RTFTGHRSNCASLDSHPFGDFFASGS--SDTNMKIW 479 + GH S HP + AS + +D +K+W Sbjct: 295 QKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 330
>WDR5_HUMAN (P61964) WD-repeat protein 5 (BMP2-induced 3-kb gene protein)| Length = 334 Score = 75.1 bits (183), Expect = 1e-13 Identities = 37/150 (24%), Positives = 70/150 (46%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMI 317 H V+ KF L + D+ + +W ++SG + +++ S ++ Sbjct: 44 HTKAVSSVKFSPN-GEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLL 102 Query: 318 GAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKR 497 + + T+KIWD+ K ++T GH + + +P + SGS D +++IWD++ + Sbjct: 103 VSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGK 162 Query: 498 CIHTYQGHTGRIDVLRFTPDGRWIVSGGAD 587 C+ T H+ + + F DG IVS D Sbjct: 163 CLKTLPAHSDPVSAVHFNRDGSLIVSSSYD 192 Score = 73.9 bits (180), Expect = 3e-13 Identities = 43/163 (26%), Positives = 76/163 (46%), Gaps = 4/163 (2%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 L+ H++ V C F + S +++G D+ V +W V + +L + PV ++ F+ Sbjct: 122 LKTLKGHSNYVFCCNFNPQ-SNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFN 180 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCAS-LDSHPFGDFFASGSSDTNMKI 476 +I + + G +IWD + ++T + S + P G + + + D +K+ Sbjct: 181 RDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKL 240 Query: 477 WDMRKKRCIHTYQGHTGR---IDVLRFTPDGRWIVSGGADSSV 596 WD K +C+ TY GH I G+WIVSG D+ V Sbjct: 241 WDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLV 283 Score = 73.2 bits (178), Expect = 5e-13 Identities = 39/128 (30%), Positives = 61/128 (47%), Gaps = 7/128 (5%) Frame = +3 Query: 237 KPTAV-------LSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGH 395 KPT V +L+G T V S+ F + + + +A IKIW + K +T +GH Sbjct: 27 KPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGH 86 Query: 396 RSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVS 575 + + + + S S D +KIWD+ +C+ T +GH+ + F P IVS Sbjct: 87 KLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVS 146 Query: 576 GGADSSVK 599 G D SV+ Sbjct: 147 GSFDESVR 154 Score = 67.8 bits (164), Expect = 2e-11 Identities = 32/141 (22%), Positives = 73/141 (51%), Gaps = 1/141 (0%) Frame = +3 Query: 180 SRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDI 359 S L++ +D+ + +W V + +L G ++ V +F+ +I +G+ +++IWD+ Sbjct: 99 SNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDV 158 Query: 360 EEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHT-YQGHTGRID 536 + K ++T H +++ + G S S D +IWD +C+ T + Sbjct: 159 KTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVS 218 Query: 537 VLRFTPDGRWIVSGGADSSVK 599 ++F+P+G++I++ D+++K Sbjct: 219 FVKFSPNGKYILAATLDNTLK 239 Score = 59.3 bits (142), Expect = 8e-09 Identities = 37/139 (26%), Positives = 63/139 (45%), Gaps = 4/139 (2%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSL-SGLTSPVESLSF 296 L+ AH+ V+ F R +++ D +W + +L PV + F Sbjct: 164 LKTLPAHSDPVSAVHFN-RDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKF 222 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSN--CASLD-SHPFGDFFASGSSDTN 467 + I A T+K+WD + K ++T+TGH++ C + S G + SGS D Sbjct: 223 SPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNL 282 Query: 468 MKIWDMRKKRCIHTYQGHT 524 + IW+++ K + QGHT Sbjct: 283 VYIWNLQTKEIVQKLQGHT 301 Score = 33.5 bits (75), Expect = 0.48 Identities = 21/96 (21%), Positives = 42/96 (43%), Gaps = 5/96 (5%) Frame = +3 Query: 207 DQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEV---MIGAGAASGTIKIWDIEEAKVV 377 D + LW K + + +G + + + S I +G+ + IW+++ ++V Sbjct: 235 DNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIV 294 Query: 378 RTFTGHRSNCASLDSHPFGDFFASGS--SDTNMKIW 479 + GH S HP + AS + +D +K+W Sbjct: 295 QKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 330
>GBB5_TAMST (Q80ZD0) Guanine nucleotide-binding protein beta subunit 5| (Transducin beta chain 5) (Gbeta5) Length = 353 Score = 75.1 bits (183), Expect = 1e-13 Identities = 34/112 (30%), Positives = 62/112 (55%), Gaps = 2/112 (1%) Frame = +3 Query: 270 TSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPF--GDFF 443 T+ + + SF +S++ I + GT +WD+E +++++F GH ++ LD P G+ F Sbjct: 153 TNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTF 212 Query: 444 ASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 SG D +WDMR +C+ ++ H I+ +R+ P G SG D++ + Sbjct: 213 VSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATCR 264 Score = 69.3 bits (168), Expect = 8e-12 Identities = 41/163 (25%), Positives = 73/163 (44%), Gaps = 3/163 (1%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFG-KRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSF 296 LQ F H +DV C T T ++GG D+K +W + V + S + S+ + Sbjct: 188 LQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRY 247 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRS--NCASLDSHPFGDFFASGSSDTNM 470 S +G+ T +++D+ + V ++ +S+D G +G +D + Sbjct: 248 YPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTI 307 Query: 471 KIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 +WD+ K + GH R+ LR +PDG SG D +++ Sbjct: 308 NVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLR 350 Score = 52.4 bits (124), Expect = 1e-06 Identities = 31/122 (25%), Positives = 55/122 (45%), Gaps = 2/122 (1%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAV--GKPTAVLSLSGLTSPVESLS 293 +Q F H SD+ ++ + +G +D L+ + + A+ S + S+ Sbjct: 232 VQAFETHESDINSVRYYP-SGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVD 290 Query: 294 FDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMK 473 F S ++ AG TI +WD+ + V GH + ++L P G F SGS D ++ Sbjct: 291 FSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLR 350 Query: 474 IW 479 +W Sbjct: 351 VW 352
>GBB5_RABIT (Q6PNB6) Guanine nucleotide-binding protein beta subunit 5| (Transducin beta chain 5) (Gbeta5) Length = 353 Score = 75.1 bits (183), Expect = 1e-13 Identities = 34/112 (30%), Positives = 62/112 (55%), Gaps = 2/112 (1%) Frame = +3 Query: 270 TSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPF--GDFF 443 T+ + + SF +S++ I + GT +WD+E +++++F GH ++ LD P G+ F Sbjct: 153 TNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTF 212 Query: 444 ASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 SG D +WDMR +C+ ++ H I+ +R+ P G SG D++ + Sbjct: 213 VSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATCR 264 Score = 69.3 bits (168), Expect = 8e-12 Identities = 41/163 (25%), Positives = 73/163 (44%), Gaps = 3/163 (1%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFG-KRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSF 296 LQ F H +DV C T T ++GG D+K +W + V + S + S+ + Sbjct: 188 LQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRY 247 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRS--NCASLDSHPFGDFFASGSSDTNM 470 S +G+ T +++D+ + V ++ +S+D G +G +D + Sbjct: 248 YPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTI 307 Query: 471 KIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 +WD+ K + GH R+ LR +PDG SG D +++ Sbjct: 308 NVWDVLKGARVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLR 350 Score = 52.0 bits (123), Expect = 1e-06 Identities = 31/122 (25%), Positives = 55/122 (45%), Gaps = 2/122 (1%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAV--GKPTAVLSLSGLTSPVESLS 293 +Q F H SD+ ++ + +G +D L+ + + A+ S + S+ Sbjct: 232 VQAFETHESDINSVRYYP-SGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVD 290 Query: 294 FDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMK 473 F S ++ AG TI +WD+ + V GH + ++L P G F SGS D ++ Sbjct: 291 FSLSGRLLFAGYNDYTINVWDVLKGARVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLR 350 Query: 474 IW 479 +W Sbjct: 351 VW 352
>GBB5_PONPY (Q5RDY7) Guanine nucleotide-binding protein beta subunit 5| (Transducin beta chain 5) (Gbeta5) Length = 353 Score = 75.1 bits (183), Expect = 1e-13 Identities = 34/112 (30%), Positives = 62/112 (55%), Gaps = 2/112 (1%) Frame = +3 Query: 270 TSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPF--GDFF 443 T+ + + SF +S++ I + GT +WD+E +++++F GH ++ LD P G+ F Sbjct: 153 TNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTF 212 Query: 444 ASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 SG D +WDMR +C+ ++ H I+ +R+ P G SG D++ + Sbjct: 213 VSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATCR 264 Score = 69.3 bits (168), Expect = 8e-12 Identities = 41/163 (25%), Positives = 73/163 (44%), Gaps = 3/163 (1%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFG-KRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSF 296 LQ F H +DV C T T ++GG D+K +W + V + S + S+ + Sbjct: 188 LQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRY 247 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRS--NCASLDSHPFGDFFASGSSDTNM 470 S +G+ T +++D+ + V ++ +S+D G +G +D + Sbjct: 248 YPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTI 307 Query: 471 KIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 +WD+ K + GH R+ LR +PDG SG D +++ Sbjct: 308 NVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLR 350 Score = 52.4 bits (124), Expect = 1e-06 Identities = 31/122 (25%), Positives = 55/122 (45%), Gaps = 2/122 (1%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAV--GKPTAVLSLSGLTSPVESLS 293 +Q F H SD+ ++ + +G +D L+ + + A+ S + S+ Sbjct: 232 VQAFETHESDINSVRYYP-SGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVD 290 Query: 294 FDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMK 473 F S ++ AG TI +WD+ + V GH + ++L P G F SGS D ++ Sbjct: 291 FSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLR 350 Query: 474 IW 479 +W Sbjct: 351 VW 352
>PRP46_SCHPO (O13615) Pre-mRNA-splicing factor prp46 (Pre-mRNA-processing| protein 5) (Complexed with cdc5 protein 1) Length = 473 Score = 75.1 bits (183), Expect = 1e-13 Identities = 47/157 (29%), Positives = 73/157 (46%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 ++ + H S V K T L+T G D +W + V LSG S V SL+ Sbjct: 240 IRHYHGHLSGVYALKLHP-TLDVLVTAGRDAVARVWDMRTRQNVHVLSGHKSTVASLAVQ 298 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 + + G+ TI++WD+ K + T T H+ +L HP FASGSSD N+K W Sbjct: 299 EFDPQVVTGSMDSTIRLWDLAAGKTLTTLTHHKKTVRALSLHPDEFTFASGSSD-NIKHW 357 Query: 480 DMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADS 590 + + ++GH ++ L D ++ GAD+ Sbjct: 358 KFPEGAFMGNFEGHNAIVNTLSINSDN--VMFSGADN 392 Score = 74.3 bits (181), Expect = 2e-13 Identities = 36/135 (26%), Positives = 63/135 (46%) Frame = +3 Query: 195 TGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKV 374 TG D+ + +W + L+L+G + V L+ + + +K WD+E KV Sbjct: 180 TGAGDRTIKIWDLASGVLKLTLTGHIATVRGLAVSPRHPYLFSCGEDKMVKCWDLETNKV 239 Query: 375 VRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTP 554 +R + GH S +L HP D + D ++WDMR ++ +H GH + L Sbjct: 240 IRHYHGHLSGVYALKLHPTLDVLVTAGRDAVARVWDMRTRQNVHVLSGHKSTVASLAVQE 299 Query: 555 DGRWIVSGGADSSVK 599 +V+G DS+++ Sbjct: 300 FDPQVVTGSMDSTIR 314 Score = 60.8 bits (146), Expect = 3e-09 Identities = 36/135 (26%), Positives = 62/135 (45%), Gaps = 1/135 (0%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSS-EVMIGAGAASGTIKIWDIEE 365 L + GED+ V W + + G S V +L + +V++ AG ++WD+ Sbjct: 220 LFSCGEDKMVKCWDLETNKVIRHYHGHLSGVYALKLHPTLDVLVTAGR-DAVARVWDMRT 278 Query: 366 AKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLR 545 + V +GH+S ASL F +GS D+ +++WD+ + + T H + L Sbjct: 279 RQNVHVLSGHKSTVASLAVQEFDPQVVTGSMDSTIRLWDLAAGKTLTTLTHHKKTVRALS 338 Query: 546 FTPDGRWIVSGGADS 590 PD SG +D+ Sbjct: 339 LHPDEFTFASGSSDN 353 Score = 55.1 bits (131), Expect = 2e-07 Identities = 32/116 (27%), Positives = 48/116 (41%) Frame = +3 Query: 243 TAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDS 422 T + +SG V + + GA TIKIWD+ + T TGH + L Sbjct: 154 TLMRVISGHLGWVRCVDVEPGNQWFCTGAGDRTIKIWDLASGVLKLTLTGHIATVRGLAV 213 Query: 423 HPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADS 590 P + S D +K WD+ + I Y GH + L+ P +V+ G D+ Sbjct: 214 SPRHPYLFSCGEDKMVKCWDLETNKVIRHYHGHLSGVYALKLHPTLDVLVTAGRDA 269 Score = 42.4 bits (98), Expect = 0.001 Identities = 22/76 (28%), Positives = 35/76 (46%) Frame = +3 Query: 372 VVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFT 551 ++R +GH +D P +F +G+ D +KIWD+ T GH + L + Sbjct: 155 LMRVISGHLGWVRCVDVEPGNQWFCTGAGDRTIKIWDLASGVLKLTLTGHIATVRGLAVS 214 Query: 552 PDGRWIVSGGADSSVK 599 P ++ S G D VK Sbjct: 215 PRHPYLFSCGEDKMVK 230
>GBB5_MOUSE (P62881) Guanine nucleotide-binding protein beta subunit 5| (Transducin beta chain 5) (Gbeta5) Length = 395 Score = 74.7 bits (182), Expect = 2e-13 Identities = 33/112 (29%), Positives = 62/112 (55%), Gaps = 2/112 (1%) Frame = +3 Query: 270 TSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPF--GDFF 443 T+ + + SF +S++ I + GT +WD+E +++++F GH ++ LD P G+ F Sbjct: 195 TNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTF 254 Query: 444 ASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 SG D +WDMR +C+ ++ H ++ +R+ P G SG D++ + Sbjct: 255 VSGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRYYPSGDAFASGSDDATCR 306 Score = 69.7 bits (169), Expect = 6e-12 Identities = 42/163 (25%), Positives = 73/163 (44%), Gaps = 3/163 (1%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFG-KRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSF 296 LQ F H +DV C T T ++GG D+K +W + V + S V S+ + Sbjct: 230 LQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRY 289 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRS--NCASLDSHPFGDFFASGSSDTNM 470 S +G+ T +++D+ + V ++ +S+D G +G +D + Sbjct: 290 YPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTI 349 Query: 471 KIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 +WD+ K + GH R+ LR +PDG SG D +++ Sbjct: 350 NVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLR 392 Score = 52.8 bits (125), Expect = 8e-07 Identities = 32/122 (26%), Positives = 55/122 (45%), Gaps = 2/122 (1%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAV--GKPTAVLSLSGLTSPVESLS 293 +Q F H SDV ++ + +G +D L+ + + A+ S + S+ Sbjct: 274 VQAFETHESDVNSVRYYP-SGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVD 332 Query: 294 FDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMK 473 F S ++ AG TI +WD+ + V GH + ++L P G F SGS D ++ Sbjct: 333 FSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLR 392 Query: 474 IW 479 +W Sbjct: 393 VW 394
>TUP1_YEAST (P16649) Glucose repression regulatory protein TUP1 (Flocculation| suppressor protein) (Repressor AER2) Length = 713 Score = 74.7 bits (182), Expect = 2e-13 Identities = 38/107 (35%), Positives = 53/107 (49%) Frame = +3 Query: 279 VESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSS 458 + S+ F + GA I+IWDIE K+V GH + SLD P GD SGS Sbjct: 446 IRSVCFSPDGKFLATGAEDRLIRIWDIENRKIVMILQGHEQDIYSLDYFPSGDKLVSGSG 505 Query: 459 DTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 D ++IWD+R +C T G V DG++I +G D +V+ Sbjct: 506 DRTVRIWDLRTGQCSLTLSIEDGVTTVAVSPGDGKYIAAGSLDRAVR 552 Score = 63.2 bits (152), Expect = 6e-10 Identities = 39/144 (27%), Positives = 64/144 (44%), Gaps = 7/144 (4%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L TG ED+ + +W + V+ L G + SL + S + +G+ T++IWD+ Sbjct: 458 LATGAEDRLIRIWDIENRKIVMILQGHEQDIYSLDYFPSGDKLVSGSGDRTVRIWDLRTG 517 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQ-------GHTG 527 + T + S G + A+GS D +++WD + GH Sbjct: 518 QCSLTLSIEDGVTTVAVSPGDGKYIAAGSLDRAVRVWDSETGFLVERLDSENESGTGHKD 577 Query: 528 RIDVLRFTPDGRWIVSGGADSSVK 599 + + FT DG+ +VSG D SVK Sbjct: 578 SVYSVVFTRDGQSVVSGSLDRSVK 601 Score = 38.5 bits (88), Expect = 0.015 Identities = 28/124 (22%), Positives = 54/124 (43%), Gaps = 18/124 (14%) Frame = +3 Query: 174 RTSRTLITGGEDQKVNLWAV------------GKPTAVLSLSGLTSPVESLSFDSSEVMI 317 R +++++G D+ V LW + T ++ G V S++ ++ I Sbjct: 586 RDGQSVVSGSLDRSVKLWNLQNANNKSDSKTPNSGTCEVTYIGHKDFVLSVATTQNDEYI 645 Query: 318 GAGAASGTIKIWDIEEAKVVRTFTGHRSNCASL---DSHPFG---DFFASGSSDTNMKIW 479 +G+ + WD + + GHR++ S+ + P G + FA+GS D +IW Sbjct: 646 LSGSKDRGVLFWDKKSGNPLLMLQGHRNSVISVAVANGSPLGPEYNVFATGSGDCKARIW 705 Query: 480 DMRK 491 +K Sbjct: 706 KYKK 709 Score = 36.2 bits (82), Expect = 0.074 Identities = 29/147 (19%), Positives = 54/147 (36%), Gaps = 19/147 (12%) Frame = +3 Query: 150 VTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSL-------SGLTSPVESLSFDSSE 308 VT + + G D+ V +W V L +G V S+ F Sbjct: 529 VTTVAVSPGDGKYIAAGSLDRAVRVWDSETGFLVERLDSENESGTGHKDSVYSVVFTRDG 588 Query: 309 VMIGAGAASGTIKIWDIEEAKVVR------------TFTGHRSNCASLDSHPFGDFFASG 452 + +G+ ++K+W+++ A T+ GH+ S+ + ++ SG Sbjct: 589 QSVVSGSLDRSVKLWNLQNANNKSDSKTPNSGTCEVTYIGHKDFVLSVATTQNDEYILSG 648 Query: 453 SSDTNMKIWDMRKKRCIHTYQGHTGRI 533 S D + WD + + QGH + Sbjct: 649 SKDRGVLFWDKKSGNPLLMLQGHRNSV 675
>PF20_CHLRE (P93107) Flagellar WD-repeat protein PF20| Length = 606 Score = 74.7 bits (182), Expect = 2e-13 Identities = 36/140 (25%), Positives = 66/140 (47%) Frame = +3 Query: 177 TSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWD 356 T L+T +D+ +W + ++ G V + F + + +G +KIWD Sbjct: 337 TKPILVTASDDKTWKMWHMPGGDLIMCGEGHKDWVAGVDFHPAGTCLASGGGDSAVKIWD 396 Query: 357 IEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRID 536 E+ + V TFT H+ S+ H G+ ASGS D +++WD+ +C +GH ++ Sbjct: 397 FEKQRCVTTFTDHKQAIWSVRFHHLGEVVASGSLDHTVRLWDLPAGKCRMALRGHVDSVN 456 Query: 537 VLRFTPDGRWIVSGGADSSV 596 L + P + + +D +V Sbjct: 457 DLAWQPFSSSLATASSDKTV 476 Score = 73.6 bits (179), Expect = 4e-13 Identities = 39/137 (28%), Positives = 60/137 (43%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L +GG D V +W K V + + + S+ F ++ +G+ T+++WD+ Sbjct: 383 LASGGGDSAVKIWDFEKQRCVTTFTDHKQAIWSVRFHHLGEVVASGSLDHTVRLWDLPAG 442 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 K GH + L PF A+ SSD + +WD R C TY GH + + F Sbjct: 443 KCRMALRGHVDSVNDLAWQPFSSSLATASSDKTVSVWDARAGLCTQTYYGHQNSCNGVSF 502 Query: 549 TPDGRWIVSGGADSSVK 599 G + S AD VK Sbjct: 503 NILGTQLASTDADGVVK 519 Score = 67.4 bits (163), Expect = 3e-11 Identities = 38/124 (30%), Positives = 62/124 (50%), Gaps = 4/124 (3%) Frame = +3 Query: 240 PTAVLSLS----GLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNC 407 P +LSL+ G V +L+ ++ ++ + T K+W + ++ GH+ Sbjct: 312 PVKMLSLNKTFKGHLLSVANLALHPTKPILVTASDDKTWKMWHMPGGDLIMCGEGHKDWV 371 Query: 408 ASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGAD 587 A +D HP G ASG D+ +KIWD K+RC+ T+ H I +RF G + SG D Sbjct: 372 AGVDFHPAGTCLASGGGDSAVKIWDFEKQRCVTTFTDHKQAIWSVRFHHLGEVVASGSLD 431 Query: 588 SSVK 599 +V+ Sbjct: 432 HTVR 435 Score = 53.5 bits (127), Expect = 4e-07 Identities = 39/199 (19%), Positives = 73/199 (36%), Gaps = 42/199 (21%) Frame = +3 Query: 129 FVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSE 308 F H + +F + +G D V LW + ++L G V L++ Sbjct: 406 FTDHKQAIWSVRF-HHLGEVVASGSLDHTVRLWDLPAGKCRMALRGHVDSVNDLAWQPFS 464 Query: 309 VMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMR 488 + ++ T+ +WD +T+ GH+++C + + G AS +D +K+WD R Sbjct: 465 SSLATASSDKTVSVWDARAGLCTQTYYGHQNSCNGVSFNILGTQLASTDADGVVKLWDTR 524 Query: 489 ---------------KKRC----------------IHTYQ-----------GHTGRIDVL 542 K C + Y GH + + Sbjct: 525 MTAEVATINTGKHPANKSCFDRSGQVLAVACDDGKVKAYSTTDGVLQAELAGHEDAVQAV 584 Query: 543 RFTPDGRWIVSGGADSSVK 599 F P G+++VS G+D++ + Sbjct: 585 LFDPAGQYLVSCGSDNTFR 603 Score = 36.6 bits (83), Expect = 0.057 Identities = 19/91 (20%), Positives = 33/91 (36%) Frame = +3 Query: 207 DQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTF 386 D V LW V +++ P FD S ++ G +K + + + Sbjct: 515 DGVVKLWDTRMTAEVATINTGKHPANKSCFDRSGQVLAVACDDGKVKAYSTTDGVLQAEL 574 Query: 387 TGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 GH ++ P G + S SD ++W Sbjct: 575 AGHEDAVQAVLFDPAGQYLVSCGSDNTFRLW 605
>GBB5_RAT (P62882) Guanine nucleotide-binding protein beta subunit 5| (Transducin beta chain 5) (Gbeta5) Length = 353 Score = 74.7 bits (182), Expect = 2e-13 Identities = 33/112 (29%), Positives = 62/112 (55%), Gaps = 2/112 (1%) Frame = +3 Query: 270 TSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPF--GDFF 443 T+ + + SF +S++ I + GT +WD+E +++++F GH ++ LD P G+ F Sbjct: 153 TNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTF 212 Query: 444 ASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 SG D +WDMR +C+ ++ H ++ +R+ P G SG D++ + Sbjct: 213 VSGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRYYPSGDAFASGSDDATCR 264 Score = 69.7 bits (169), Expect = 6e-12 Identities = 42/163 (25%), Positives = 73/163 (44%), Gaps = 3/163 (1%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFG-KRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSF 296 LQ F H +DV C T T ++GG D+K +W + V + S V S+ + Sbjct: 188 LQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRY 247 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRS--NCASLDSHPFGDFFASGSSDTNM 470 S +G+ T +++D+ + V ++ +S+D G +G +D + Sbjct: 248 YPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTI 307 Query: 471 KIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 +WD+ K + GH R+ LR +PDG SG D +++ Sbjct: 308 NVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLR 350 Score = 52.8 bits (125), Expect = 8e-07 Identities = 32/122 (26%), Positives = 55/122 (45%), Gaps = 2/122 (1%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAV--GKPTAVLSLSGLTSPVESLS 293 +Q F H SDV ++ + +G +D L+ + + A+ S + S+ Sbjct: 232 VQAFETHESDVNSVRYYP-SGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVD 290 Query: 294 FDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMK 473 F S ++ AG TI +WD+ + V GH + ++L P G F SGS D ++ Sbjct: 291 FSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLR 350 Query: 474 IW 479 +W Sbjct: 351 VW 352
>ATG16_XENTR (Q5I0B9) Autophagy-related protein 16 (APG16-like 1)| Length = 537 Score = 74.3 bits (181), Expect = 2e-13 Identities = 46/135 (34%), Positives = 67/135 (49%), Gaps = 2/135 (1%) Frame = +3 Query: 111 AYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAV--GKPTAVLSLSGLTSPVE 284 A + F AH +V +F SR L TGG D++V LW V K A SL+G + + Sbjct: 242 ATAVYSFDAHDGEVNAVRFSPG-SRLLATGGMDRRVKLWDVIGNKCEAKGSLTGSNAGIT 300 Query: 285 SLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDT 464 S+ FDS+ + A + +IW +++ ++ T TGH S SGS D Sbjct: 301 SIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDR 360 Query: 465 NMKIWDMRKKRCIHT 509 +K+WD+R K CI T Sbjct: 361 TLKLWDLRSKVCIKT 375 Score = 60.1 bits (144), Expect = 5e-09 Identities = 32/121 (26%), Positives = 56/121 (46%), Gaps = 2/121 (1%) Frame = +3 Query: 243 TAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDI--EEAKVVRTFTGHRSNCASL 416 TAV S V ++ F ++ G +K+WD+ + + + TG + S+ Sbjct: 243 TAVYSFDAHDGEVNAVRFSPGSRLLATGGMDRRVKLWDVIGNKCEAKGSLTGSNAGITSI 302 Query: 417 DSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 + G + + S+D +IW + R HT GH+G++ +F D IVSG D ++ Sbjct: 303 EFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTL 362 Query: 597 K 599 K Sbjct: 363 K 363 Score = 30.0 bits (66), Expect = 5.3 Identities = 16/56 (28%), Positives = 27/56 (48%), Gaps = 1/56 (1%) Frame = +3 Query: 315 IGAGAASGTIKIWDIEEAKVVRTFT-GHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 + AG+A GT+ W++ KV R F+ H S+ ++ P G S + +W Sbjct: 479 VSAGSAEGTLYFWNVLTGKVERMFSKQHSSSINAVAWSPSGTHVVSVDKGSRGVLW 534
>YKY4_CAEEL (Q17963) Hypothetical WD-repeat protein C14B1.4| Length = 376 Score = 74.3 bits (181), Expect = 2e-13 Identities = 43/163 (26%), Positives = 76/163 (46%), Gaps = 1/163 (0%) Frame = +3 Query: 114 YKLQ-EFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESL 290 YKL H ++ AKF + L T D+ V +W + +L+G V + Sbjct: 77 YKLMCTLEGHTKSISSAKFSP-CGKYLGTSSADKTVKIWNMDHMICERTLTGHKLGVNDI 135 Query: 291 SFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNM 470 ++ S + + + T+KI++I +++ +T GH + + +P SGS D ++ Sbjct: 136 AWSSDSRCVVSASDDKTLKIFEIVTSRMTKTLKGHNNYVFCCNFNPQSSLVVSGSFDESV 195 Query: 471 KIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 +IWD++ CI T H+ + + F DG I SG D V+ Sbjct: 196 RIWDVKTGMCIKTLPAHSDPVSAVSFNRDGSLIASGSYDGLVR 238 Score = 68.2 bits (165), Expect = 2e-11 Identities = 32/141 (22%), Positives = 74/141 (52%), Gaps = 1/141 (0%) Frame = +3 Query: 180 SRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDI 359 SR +++ +D+ + ++ + +L G + V +F+ ++ +G+ +++IWD+ Sbjct: 141 SRCVVSASDDKTLKIFEIVTSRMTKTLKGHNNYVFCCNFNPQSSLVVSGSFDESVRIWDV 200 Query: 360 EEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHT-YQGHTGRID 536 + ++T H +++ + G ASGS D ++IWD +CI T + Sbjct: 201 KTGMCIKTLPAHSDPVSAVSFNRDGSLIASGSYDGLVRIWDTANGQCIKTLVDDENPPVA 260 Query: 537 VLRFTPDGRWIVSGGADSSVK 599 ++F+P+G++I++ DS++K Sbjct: 261 FVKFSPNGKYILASNLDSTLK 281 Score = 58.5 bits (140), Expect = 1e-08 Identities = 40/159 (25%), Positives = 68/159 (42%), Gaps = 4/159 (2%) Frame = +3 Query: 135 AHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSL-SGLTSPVESLSFDSSEV 311 AH+ V+ F R + +G D V +W + +L PV + F + Sbjct: 211 AHSDPVSAVSFN-RDGSLIASGSYDGLVRIWDTANGQCIKTLVDDENPPVAFVKFSPNGK 269 Query: 312 MIGAGAASGTIKIWDIEEAKVVRTFTGHRSN--CASLD-SHPFGDFFASGSSDTNMKIWD 482 I A T+K+WD + K ++ +TGH ++ C + S G + SGS D + IW+ Sbjct: 270 YILASNLDSTLKLWDFSKGKTLKQYTGHENSKYCIFANFSVTGGKWIISGSEDCKIYIWN 329 Query: 483 MRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 ++ + + +GHT + P I SG + K Sbjct: 330 LQTREIVQCLEGHTQPVLASDCHPVQNIIASGALEPDNK 368 Score = 35.8 bits (81), Expect = 0.097 Identities = 24/100 (24%), Positives = 44/100 (44%), Gaps = 4/100 (4%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGT----IKIWD 356 ++ D + LW K + +G + + F + V G SG+ I IW+ Sbjct: 271 ILASNLDSTLKLWDFSKGKTLKQYTGHENSKYCI-FANFSVTGGKWIISGSEDCKIYIWN 329 Query: 357 IEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 ++ ++V+ GH + D HP + ASG+ + + KI Sbjct: 330 LQTREIVQCLEGHTQPVLASDCHPVQNIIASGALEPDNKI 369
>PRP4_PONPY (Q5NVD0) U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60| kDa protein) (WD splicing factor Prp4) Length = 521 Score = 73.9 bits (180), Expect = 3e-13 Identities = 36/142 (25%), Positives = 67/142 (47%), Gaps = 1/142 (0%) Frame = +3 Query: 177 TSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWD 356 + R L T D+ LW + +L G + V ++F + G G ++WD Sbjct: 333 SGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWD 392 Query: 357 IEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRID 536 + + + GH ++ P G A+GS D K+WD+R++RC++T H + Sbjct: 393 LRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVT 452 Query: 537 VLRFTP-DGRWIVSGGADSSVK 599 ++F P G ++++G D++ K Sbjct: 453 GVKFEPIHGNFLLTGAYDNTAK 474 Score = 67.0 bits (162), Expect = 4e-11 Identities = 35/131 (26%), Positives = 59/131 (45%) Frame = +3 Query: 207 DQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTF 386 D V LW++ V + G T V + + S +G + ++WD+E + + Sbjct: 301 DGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQ 360 Query: 387 TGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRW 566 GH + H G +G D ++WD+R RCI +GH I + F+P+G Sbjct: 361 EGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYH 420 Query: 567 IVSGGADSSVK 599 I +G D++ K Sbjct: 421 IATGSGDNTCK 431 Score = 63.9 bits (154), Expect = 3e-10 Identities = 35/136 (25%), Positives = 61/136 (44%), Gaps = 1/136 (0%) Frame = +3 Query: 195 TGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKV 374 TGG D +W + ++ L G + ++F + I G+ T K+WD+ + + Sbjct: 381 TGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRC 440 Query: 375 VRTFTGHRSNCASLDSHPF-GDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFT 551 V T H++ + P G+F +G+ D KIW + T GH G++ L + Sbjct: 441 VYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDIS 500 Query: 552 PDGRWIVSGGADSSVK 599 DG+ I + D + K Sbjct: 501 SDGQLIATCSYDRTFK 516 Score = 61.2 bits (147), Expect = 2e-09 Identities = 37/145 (25%), Positives = 66/145 (45%), Gaps = 8/145 (5%) Frame = +3 Query: 180 SRTLITGGEDQKVNLWAVGKPTAVLSLSGLTS--------PVESLSFDSSEVMIGAGAAS 335 S+ L T LW+V + +L G + P ++S D +V + + AA Sbjct: 242 SKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDQKDVNLASCAAD 301 Query: 336 GTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQ 515 G++K+W ++ + V GH A + HP G F + D + ++WD+ + I + Sbjct: 302 GSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQE 361 Query: 516 GHTGRIDVLRFTPDGRWIVSGGADS 590 GH+ + + F DG +GG D+ Sbjct: 362 GHSMGVYDIAFHQDGSLAGTGGLDA 386 Score = 53.1 bits (126), Expect = 6e-07 Identities = 25/106 (23%), Positives = 49/106 (46%), Gaps = 8/106 (7%) Frame = +3 Query: 276 PVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDF----- 440 P+ F + M+ SG K+W + + ++ T GH +N ++ HP Sbjct: 232 PISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDQK 291 Query: 441 ---FASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWI 569 AS ++D ++K+W + + +GHT R+ + + P GR++ Sbjct: 292 DVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFL 337 Score = 38.5 bits (88), Expect = 0.015 Identities = 24/98 (24%), Positives = 38/98 (38%), Gaps = 1/98 (1%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEV-MIGAGAASGTIKIWDIEE 365 + TG D +W + + V ++ + V + F+ + GA T KIW Sbjct: 421 IATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPG 480 Query: 366 AKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 ++T GH LD G A+ S D K+W Sbjct: 481 WSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 518 Score = 32.7 bits (73), Expect = 0.82 Identities = 21/76 (27%), Positives = 31/76 (40%) Frame = +3 Query: 135 AHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVM 314 AH + VT KF L+TG D +W + + +L+G V L S + Sbjct: 446 AHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQL 505 Query: 315 IGAGAASGTIKIWDIE 362 I + T K+W E Sbjct: 506 IATCSYDRTFKLWMAE 521
>GBB_DICDI (P36408) Guanine nucleotide-binding protein beta subunit| Length = 347 Score = 73.9 bits (180), Expect = 3e-13 Identities = 44/157 (28%), Positives = 76/157 (48%), Gaps = 2/157 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 +E +H ++C +F R ++T D LW V T + S V S+S Sbjct: 144 RELNSHTGYLSCCRF--LNDRQIVTSSGDMTCILWDVENGTKITEFSDHNGDVMSVSVSP 201 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 + +GA T K+WD+ K V+TFTGH ++ ++ P G F +GS D + +++D Sbjct: 202 DKNYFISGACDATAKLWDLRSGKCVQTFTGHEADINAVQYFPNGLSFGTGSDDASCRLFD 261 Query: 483 MRKKRCI--HTYQGHTGRIDVLRFTPDGRWIVSGGAD 587 +R R + +T+ I + F+ GR++ +G D Sbjct: 262 IRADRELMQYTHDNILCGITSVGFSFSGRFLFAGYDD 298 Score = 65.9 bits (159), Expect = 9e-11 Identities = 26/87 (29%), Positives = 48/87 (55%) Frame = +3 Query: 339 TIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQG 518 T +WD+E + F+ H + S+ P ++F SG+ D K+WD+R +C+ T+ G Sbjct: 172 TCILWDVENGTKITEFSDHNGDVMSVSVSPDKNYFISGACDATAKLWDLRSGKCVQTFTG 231 Query: 519 HTGRIDVLRFTPDGRWIVSGGADSSVK 599 H I+ +++ P+G +G D+S + Sbjct: 232 HEADINAVQYFPNGLSFGTGSDDASCR 258 Score = 42.0 bits (97), Expect = 0.001 Identities = 28/122 (22%), Positives = 53/122 (43%), Gaps = 2/122 (1%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLS--GLTSPVESLS 293 +Q F H +D+ ++ + TG +D L+ + ++ + + + S+ Sbjct: 226 VQTFTGHEADINAVQYFPN-GLSFGTGSDDASCRLFDIRADRELMQYTHDNILCGITSVG 284 Query: 294 FDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMK 473 F S + AG T +WD + + V + TGH + + L G +GS D+ +K Sbjct: 285 FSFSGRFLFAGYDDFTCNVWDTLKGERVLSLTGHGNRVSCLGVPTDGMALCTGSWDSLLK 344 Query: 474 IW 479 IW Sbjct: 345 IW 346 Score = 40.8 bits (94), Expect = 0.003 Identities = 27/144 (18%), Positives = 59/144 (40%), Gaps = 7/144 (4%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEE- 365 L++ +D K+ +W V ++ +S V + ++ + + G I+++ Sbjct: 77 LVSASQDGKLLVWDGLTTNKVHAIPLRSSWVMTCAYSPTANFVACGGLDNICSIYNLRSR 136 Query: 366 ------AKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTG 527 + + + TG+ S C L+ + S D +WD+ I + H G Sbjct: 137 EQPIRVCRELNSHTGYLSCCRFLNDRQI----VTSSGDMTCILWDVENGTKITEFSDHNG 192 Query: 528 RIDVLRFTPDGRWIVSGGADSSVK 599 + + +PD + +SG D++ K Sbjct: 193 DVMSVSVSPDKNYFISGACDATAK 216
>PRP4_HUMAN (O43172) U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60| kDa protein) (WD splicing factor Prp4) (hPrp4) Length = 522 Score = 73.9 bits (180), Expect = 3e-13 Identities = 36/142 (25%), Positives = 67/142 (47%), Gaps = 1/142 (0%) Frame = +3 Query: 177 TSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWD 356 + R L T D+ LW + +L G + V ++F + G G ++WD Sbjct: 334 SGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWD 393 Query: 357 IEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRID 536 + + + GH ++ P G A+GS D K+WD+R++RC++T H + Sbjct: 394 LRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVT 453 Query: 537 VLRFTP-DGRWIVSGGADSSVK 599 ++F P G ++++G D++ K Sbjct: 454 GVKFEPIHGNFLLTGAYDNTAK 475 Score = 67.0 bits (162), Expect = 4e-11 Identities = 35/131 (26%), Positives = 59/131 (45%) Frame = +3 Query: 207 DQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTF 386 D V LW++ V + G T V + + S +G + ++WD+E + + Sbjct: 302 DGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQ 361 Query: 387 TGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRW 566 GH + H G +G D ++WD+R RCI +GH I + F+P+G Sbjct: 362 EGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYH 421 Query: 567 IVSGGADSSVK 599 I +G D++ K Sbjct: 422 IATGSGDNTCK 432 Score = 63.9 bits (154), Expect = 3e-10 Identities = 35/136 (25%), Positives = 61/136 (44%), Gaps = 1/136 (0%) Frame = +3 Query: 195 TGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKV 374 TGG D +W + ++ L G + ++F + I G+ T K+WD+ + + Sbjct: 382 TGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRC 441 Query: 375 VRTFTGHRSNCASLDSHPF-GDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFT 551 V T H++ + P G+F +G+ D KIW + T GH G++ L + Sbjct: 442 VYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDIS 501 Query: 552 PDGRWIVSGGADSSVK 599 DG+ I + D + K Sbjct: 502 SDGQLIATCSYDRTFK 517 Score = 60.8 bits (146), Expect = 3e-09 Identities = 37/145 (25%), Positives = 66/145 (45%), Gaps = 8/145 (5%) Frame = +3 Query: 180 SRTLITGGEDQKVNLWAVGKPTAVLSLSGLTS--------PVESLSFDSSEVMIGAGAAS 335 S+ L T LW+V + +L G + P ++S D +V + + AA Sbjct: 243 SKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAAD 302 Query: 336 GTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQ 515 G++K+W ++ + V GH A + HP G F + D + ++WD+ + I + Sbjct: 303 GSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQE 362 Query: 516 GHTGRIDVLRFTPDGRWIVSGGADS 590 GH+ + + F DG +GG D+ Sbjct: 363 GHSMGVYDIAFHQDGSLAGTGGLDA 387 Score = 53.1 bits (126), Expect = 6e-07 Identities = 25/106 (23%), Positives = 49/106 (46%), Gaps = 8/106 (7%) Frame = +3 Query: 276 PVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDF----- 440 P+ F + M+ SG K+W + + ++ T GH +N ++ HP Sbjct: 233 PISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPK 292 Query: 441 ---FASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWI 569 AS ++D ++K+W + + +GHT R+ + + P GR++ Sbjct: 293 DVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFL 338 Score = 38.5 bits (88), Expect = 0.015 Identities = 24/98 (24%), Positives = 38/98 (38%), Gaps = 1/98 (1%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEV-MIGAGAASGTIKIWDIEE 365 + TG D +W + + V ++ + V + F+ + GA T KIW Sbjct: 422 IATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPG 481 Query: 366 AKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 ++T GH LD G A+ S D K+W Sbjct: 482 WSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 519 Score = 32.7 bits (73), Expect = 0.82 Identities = 21/76 (27%), Positives = 31/76 (40%) Frame = +3 Query: 135 AHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVM 314 AH + VT KF L+TG D +W + + +L+G V L S + Sbjct: 447 AHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQL 506 Query: 315 IGAGAASGTIKIWDIE 362 I + T K+W E Sbjct: 507 IATCSYDRTFKLWMAE 522
>TUP1_CANAL (P56093) Transcriptional repressor TUP1| Length = 514 Score = 73.9 bits (180), Expect = 3e-13 Identities = 34/107 (31%), Positives = 57/107 (53%) Frame = +3 Query: 279 VESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSS 458 + S+ F ++ GA I+IWD+ ++++ GH + SLD P GD SGS Sbjct: 260 IRSVCFSPDGKLLATGAEDKLIRIWDLSTKRIIKILRGHEQDIYSLDFFPDGDRLVSGSG 319 Query: 459 DTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 D +++IWD+R +C T G + + +PDG+ I +G D +V+ Sbjct: 320 DRSVRIWDLRTSQCSLTLSIEDG-VTTVAVSPDGKLIAAGSLDRTVR 365 Score = 66.6 bits (161), Expect = 5e-11 Identities = 49/179 (27%), Positives = 80/179 (44%), Gaps = 12/179 (6%) Frame = +3 Query: 96 MATKRAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTS 275 ++TKR K+ H D+ F R L++G D+ V +W + L+LS + Sbjct: 286 LSTKRIIKILR--GHEQDIYSLDFFPDGDR-LVSGSGDRSVRIWDLRTSQCSLTLS-IED 341 Query: 276 PVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTF-------TGHRSNCASLDSHPFG 434 V +++ +I AG+ T+++WD +V GH + S+ G Sbjct: 342 GVTTVAVSPDGKLIAAGSLDRTVRVWDSTTGFLVERLDSGNENGNGHEDSVYSVAFSNNG 401 Query: 435 DFFASGSSDTNMKIWDM-----RKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 + ASGS D +K+W + +K C TY GH + + TPD +I+SG D V Sbjct: 402 EQIASGSLDRTVKLWHLEGKSDKKSTCEVTYIGHKDFVLSVCCTPDNEYILSGSKDRGV 460 Score = 55.5 bits (132), Expect = 1e-07 Identities = 34/146 (23%), Positives = 63/146 (43%), Gaps = 7/146 (4%) Frame = +3 Query: 183 RTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIE 362 + L TG ED+ + +W + + L G + SL F + +G+ +++IWD+ Sbjct: 270 KLLATGAEDKLIRIWDLSTKRIIKILRGHEQDIYSLDFFPDGDRLVSGSGDRSVRIWDLR 329 Query: 363 EAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTY-------QGH 521 ++ T + ++ P G A+GS D +++WD + GH Sbjct: 330 TSQCSLTLS-IEDGVTTVAVSPDGKLIAAGSLDRTVRVWDSTTGFLVERLDSGNENGNGH 388 Query: 522 TGRIDVLRFTPDGRWIVSGGADSSVK 599 + + F+ +G I SG D +VK Sbjct: 389 EDSVYSVAFSNNGEQIASGSLDRTVK 414 Score = 45.1 bits (105), Expect = 2e-04 Identities = 30/129 (23%), Positives = 54/129 (41%), Gaps = 12/129 (9%) Frame = +3 Query: 183 RTLITGGEDQKVNLWAVGKPTAVLSL-------SGLTSPVESLSFDSSEVMIGAGAASGT 341 + + G D+ V +W V L +G V S++F ++ I +G+ T Sbjct: 353 KLIAAGSLDRTVRVWDSTTGFLVERLDSGNENGNGHEDSVYSVAFSNNGEQIASGSLDRT 412 Query: 342 IKIWDIE-----EAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIH 506 +K+W +E ++ T+ GH+ S+ P ++ SGS D + WD + Sbjct: 413 VKLWHLEGKSDKKSTCEVTYIGHKDFVLSVCCTPDNEYILSGSKDRGVIFWDQASGNPLL 472 Query: 507 TYQGHTGRI 533 QGH + Sbjct: 473 MLQGHRNSV 481
>GBB1_RAT (P54311) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 73.6 bits (179), Expect = 4e-13 Identities = 43/157 (27%), Positives = 74/157 (47%), Gaps = 2/157 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 +E H ++C +F ++T D LW + + +G T V SLS Sbjct: 136 RELAGHTGYLSCCRF--LDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAP 193 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 + +GA + K+WD+ E +TFTGH S+ ++ P G+ FA+GS D +++D Sbjct: 194 DTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFD 253 Query: 483 MRKKRCIHTYQGHT--GRIDVLRFTPDGRWIVSGGAD 587 +R + + TY I + F+ GR +++G D Sbjct: 254 LRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDD 290 Score = 71.2 bits (173), Expect = 2e-12 Identities = 37/115 (32%), Positives = 60/115 (52%), Gaps = 1/115 (0%) Frame = +3 Query: 258 LSGLTSPVESLSF-DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFG 434 L+G T + F D ++++ +G T +WDIE + TFTGH + SL P Sbjct: 138 LAGHTGYLSCCRFLDDNQIVTSSGDT--TCALWDIETGQQTTTFTGHTGDVMSLSLAPDT 195 Query: 435 DFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 F SG+ D + K+WD+R+ C T+ GH I+ + F P+G +G D++ + Sbjct: 196 RLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCR 250 Score = 43.1 bits (100), Expect = 6e-04 Identities = 31/122 (25%), Positives = 51/122 (41%), Gaps = 2/122 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLS--GLTSPVESLSF 296 Q F H SD+ F TG +D L+ + +++ S + + S+SF Sbjct: 219 QTFTGHESDINAICFFPN-GNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSF 277 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 S ++ AG +WD +A GH + + L G A+GS D+ +KI Sbjct: 278 SKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKI 337 Query: 477 WD 482 W+ Sbjct: 338 WN 339 Score = 32.7 bits (73), Expect = 0.82 Identities = 16/71 (22%), Positives = 27/71 (38%) Frame = +3 Query: 378 RTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPD 557 RT GH + ++ S S D + IWD +H + + + P Sbjct: 48 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPS 107 Query: 558 GRWIVSGGADS 590 G ++ GG D+ Sbjct: 108 GNYVACGGLDN 118
>GBB1_PONPY (Q5R5W8) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 73.6 bits (179), Expect = 4e-13 Identities = 43/157 (27%), Positives = 74/157 (47%), Gaps = 2/157 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 +E H ++C +F ++T D LW + + +G T V SLS Sbjct: 136 RELAGHTGYLSCCRF--LDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAP 193 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 + +GA + K+WD+ E +TFTGH S+ ++ P G+ FA+GS D +++D Sbjct: 194 DTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFD 253 Query: 483 MRKKRCIHTYQGHT--GRIDVLRFTPDGRWIVSGGAD 587 +R + + TY I + F+ GR +++G D Sbjct: 254 LRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDD 290 Score = 71.2 bits (173), Expect = 2e-12 Identities = 37/115 (32%), Positives = 60/115 (52%), Gaps = 1/115 (0%) Frame = +3 Query: 258 LSGLTSPVESLSF-DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFG 434 L+G T + F D ++++ +G T +WDIE + TFTGH + SL P Sbjct: 138 LAGHTGYLSCCRFLDDNQIVTSSGDT--TCALWDIETGQQTTTFTGHTGDVMSLSLAPDT 195 Query: 435 DFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 F SG+ D + K+WD+R+ C T+ GH I+ + F P+G +G D++ + Sbjct: 196 RLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCR 250 Score = 42.7 bits (99), Expect = 8e-04 Identities = 31/122 (25%), Positives = 50/122 (40%), Gaps = 2/122 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLS--GLTSPVESLSF 296 Q F H SD+ F TG +D L+ + +++ S + + S+SF Sbjct: 219 QTFTGHESDINAICFFPN-GNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSF 277 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 S ++ AG +WD +A GH + L G A+GS D+ +KI Sbjct: 278 SKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDDRVSCLGVTDDGMAVATGSWDSFLKI 337 Query: 477 WD 482 W+ Sbjct: 338 WN 339 Score = 32.7 bits (73), Expect = 0.82 Identities = 16/71 (22%), Positives = 27/71 (38%) Frame = +3 Query: 378 RTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPD 557 RT GH + ++ S S D + IWD +H + + + P Sbjct: 48 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPS 107 Query: 558 GRWIVSGGADS 590 G ++ GG D+ Sbjct: 108 GNYVACGGLDN 118
>GBB1_MOUSE (P62874) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 73.6 bits (179), Expect = 4e-13 Identities = 43/157 (27%), Positives = 74/157 (47%), Gaps = 2/157 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 +E H ++C +F ++T D LW + + +G T V SLS Sbjct: 136 RELAGHTGYLSCCRF--LDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAP 193 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 + +GA + K+WD+ E +TFTGH S+ ++ P G+ FA+GS D +++D Sbjct: 194 DTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFD 253 Query: 483 MRKKRCIHTYQGHT--GRIDVLRFTPDGRWIVSGGAD 587 +R + + TY I + F+ GR +++G D Sbjct: 254 LRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDD 290 Score = 71.2 bits (173), Expect = 2e-12 Identities = 37/115 (32%), Positives = 60/115 (52%), Gaps = 1/115 (0%) Frame = +3 Query: 258 LSGLTSPVESLSF-DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFG 434 L+G T + F D ++++ +G T +WDIE + TFTGH + SL P Sbjct: 138 LAGHTGYLSCCRFLDDNQIVTSSGDT--TCALWDIETGQQTTTFTGHTGDVMSLSLAPDT 195 Query: 435 DFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 F SG+ D + K+WD+R+ C T+ GH I+ + F P+G +G D++ + Sbjct: 196 RLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCR 250 Score = 43.1 bits (100), Expect = 6e-04 Identities = 31/122 (25%), Positives = 51/122 (41%), Gaps = 2/122 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLS--GLTSPVESLSF 296 Q F H SD+ F TG +D L+ + +++ S + + S+SF Sbjct: 219 QTFTGHESDINAICFFPN-GNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSF 277 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 S ++ AG +WD +A GH + + L G A+GS D+ +KI Sbjct: 278 SKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKI 337 Query: 477 WD 482 W+ Sbjct: 338 WN 339 Score = 32.7 bits (73), Expect = 0.82 Identities = 16/71 (22%), Positives = 27/71 (38%) Frame = +3 Query: 378 RTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPD 557 RT GH + ++ S S D + IWD +H + + + P Sbjct: 48 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPS 107 Query: 558 GRWIVSGGADS 590 G ++ GG D+ Sbjct: 108 GNYVACGGLDN 118
>GBB1_HUMAN (P62873) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 73.6 bits (179), Expect = 4e-13 Identities = 43/157 (27%), Positives = 74/157 (47%), Gaps = 2/157 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 +E H ++C +F ++T D LW + + +G T V SLS Sbjct: 136 RELAGHTGYLSCCRF--LDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAP 193 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 + +GA + K+WD+ E +TFTGH S+ ++ P G+ FA+GS D +++D Sbjct: 194 DTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFD 253 Query: 483 MRKKRCIHTYQGHT--GRIDVLRFTPDGRWIVSGGAD 587 +R + + TY I + F+ GR +++G D Sbjct: 254 LRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDD 290 Score = 71.2 bits (173), Expect = 2e-12 Identities = 37/115 (32%), Positives = 60/115 (52%), Gaps = 1/115 (0%) Frame = +3 Query: 258 LSGLTSPVESLSF-DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFG 434 L+G T + F D ++++ +G T +WDIE + TFTGH + SL P Sbjct: 138 LAGHTGYLSCCRFLDDNQIVTSSGDT--TCALWDIETGQQTTTFTGHTGDVMSLSLAPDT 195 Query: 435 DFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 F SG+ D + K+WD+R+ C T+ GH I+ + F P+G +G D++ + Sbjct: 196 RLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCR 250 Score = 43.1 bits (100), Expect = 6e-04 Identities = 31/122 (25%), Positives = 51/122 (41%), Gaps = 2/122 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLS--GLTSPVESLSF 296 Q F H SD+ F TG +D L+ + +++ S + + S+SF Sbjct: 219 QTFTGHESDINAICFFPN-GNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSF 277 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 S ++ AG +WD +A GH + + L G A+GS D+ +KI Sbjct: 278 SKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKI 337 Query: 477 WD 482 W+ Sbjct: 338 WN 339 Score = 32.7 bits (73), Expect = 0.82 Identities = 16/71 (22%), Positives = 27/71 (38%) Frame = +3 Query: 378 RTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPD 557 RT GH + ++ S S D + IWD +H + + + P Sbjct: 48 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPS 107 Query: 558 GRWIVSGGADS 590 G ++ GG D+ Sbjct: 108 GNYVACGGLDN 118
>GBB1_CANFA (P62872) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 73.6 bits (179), Expect = 4e-13 Identities = 43/157 (27%), Positives = 74/157 (47%), Gaps = 2/157 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 +E H ++C +F ++T D LW + + +G T V SLS Sbjct: 136 RELAGHTGYLSCCRF--LDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAP 193 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 + +GA + K+WD+ E +TFTGH S+ ++ P G+ FA+GS D +++D Sbjct: 194 DTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFD 253 Query: 483 MRKKRCIHTYQGHT--GRIDVLRFTPDGRWIVSGGAD 587 +R + + TY I + F+ GR +++G D Sbjct: 254 LRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDD 290 Score = 71.2 bits (173), Expect = 2e-12 Identities = 37/115 (32%), Positives = 60/115 (52%), Gaps = 1/115 (0%) Frame = +3 Query: 258 LSGLTSPVESLSF-DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFG 434 L+G T + F D ++++ +G T +WDIE + TFTGH + SL P Sbjct: 138 LAGHTGYLSCCRFLDDNQIVTSSGDT--TCALWDIETGQQTTTFTGHTGDVMSLSLAPDT 195 Query: 435 DFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 F SG+ D + K+WD+R+ C T+ GH I+ + F P+G +G D++ + Sbjct: 196 RLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCR 250 Score = 43.1 bits (100), Expect = 6e-04 Identities = 31/122 (25%), Positives = 51/122 (41%), Gaps = 2/122 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLS--GLTSPVESLSF 296 Q F H SD+ F TG +D L+ + +++ S + + S+SF Sbjct: 219 QTFTGHESDINAICFFPN-GNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSF 277 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 S ++ AG +WD +A GH + + L G A+GS D+ +KI Sbjct: 278 SKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKI 337 Query: 477 WD 482 W+ Sbjct: 338 WN 339 Score = 32.7 bits (73), Expect = 0.82 Identities = 16/71 (22%), Positives = 27/71 (38%) Frame = +3 Query: 378 RTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPD 557 RT GH + ++ S S D + IWD +H + + + P Sbjct: 48 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPS 107 Query: 558 GRWIVSGGADS 590 G ++ GG D+ Sbjct: 108 GNYVACGGLDN 118
>GBB1_BOVIN (P62871) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 73.6 bits (179), Expect = 4e-13 Identities = 43/157 (27%), Positives = 74/157 (47%), Gaps = 2/157 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 +E H ++C +F ++T D LW + + +G T V SLS Sbjct: 136 RELAGHTGYLSCCRF--LDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAP 193 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 + +GA + K+WD+ E +TFTGH S+ ++ P G+ FA+GS D +++D Sbjct: 194 DTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFD 253 Query: 483 MRKKRCIHTYQGHT--GRIDVLRFTPDGRWIVSGGAD 587 +R + + TY I + F+ GR +++G D Sbjct: 254 LRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDD 290 Score = 71.2 bits (173), Expect = 2e-12 Identities = 37/115 (32%), Positives = 60/115 (52%), Gaps = 1/115 (0%) Frame = +3 Query: 258 LSGLTSPVESLSF-DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFG 434 L+G T + F D ++++ +G T +WDIE + TFTGH + SL P Sbjct: 138 LAGHTGYLSCCRFLDDNQIVTSSGDT--TCALWDIETGQQTTTFTGHTGDVMSLSLAPDT 195 Query: 435 DFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 F SG+ D + K+WD+R+ C T+ GH I+ + F P+G +G D++ + Sbjct: 196 RLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCR 250 Score = 43.1 bits (100), Expect = 6e-04 Identities = 31/122 (25%), Positives = 51/122 (41%), Gaps = 2/122 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLS--GLTSPVESLSF 296 Q F H SD+ F TG +D L+ + +++ S + + S+SF Sbjct: 219 QTFTGHESDINAICFFPN-GNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSF 277 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 S ++ AG +WD +A GH + + L G A+GS D+ +KI Sbjct: 278 SKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKI 337 Query: 477 WD 482 W+ Sbjct: 338 WN 339 Score = 32.7 bits (73), Expect = 0.82 Identities = 16/71 (22%), Positives = 27/71 (38%) Frame = +3 Query: 378 RTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPD 557 RT GH + ++ S S D + IWD +H + + + P Sbjct: 48 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPS 107 Query: 558 GRWIVSGGADS 590 G ++ GG D+ Sbjct: 108 GNYVACGGLDN 118
>TUP11_SCHPO (Q09715) Transcriptional repressor tup11| Length = 614 Score = 73.2 bits (178), Expect = 5e-13 Identities = 44/169 (26%), Positives = 75/169 (44%), Gaps = 12/169 (7%) Frame = +3 Query: 129 FVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSE 308 F H D+ F R +++G D+ LW V +L L + + V +++ ++ Sbjct: 398 FSGHEQDIYSLDFS-HNGRFIVSGSGDRTARLWDVETGQCILKLE-IENGVTAIAISPND 455 Query: 309 VMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMR 488 I G+ I++W + V R GH+ + S+ P SGS D +K+W+++ Sbjct: 456 QFIAVGSLDQIIRVWSVSGTLVER-LEGHKESVYSIAFSPDSSILLSGSLDKTIKVWELQ 514 Query: 489 KKR------------CIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 R C TY GHT + + +PD RW +SG D S++ Sbjct: 515 ATRSVGLSAIKPEGICKATYTGHTDFVLSVAVSPDSRWGLSGSKDRSMQ 563 Score = 72.4 bits (176), Expect = 9e-13 Identities = 43/145 (29%), Positives = 69/145 (47%), Gaps = 12/145 (8%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 + G DQ + +W+V T V L G V S++F ++ +G+ TIK+W+++ Sbjct: 458 IAVGSLDQIIRVWSVSG-TLVERLEGHKESVYSIAFSPDSSILLSGSLDKTIKVWELQAT 516 Query: 369 KVV------------RTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTY 512 + V T+TGH S+ P + SGS D +M+ WD++ + T Sbjct: 517 RSVGLSAIKPEGICKATYTGHTDFVLSVAVSPDSRWGLSGSKDRSMQFWDLQTGQSYLTC 576 Query: 513 QGHTGRIDVLRFTPDGRWIVSGGAD 587 QGH + + F+PDGR SG D Sbjct: 577 QGHKNSVISVCFSPDGRQFASGSGD 601 Score = 64.3 bits (155), Expect = 3e-10 Identities = 48/176 (27%), Positives = 78/176 (44%), Gaps = 9/176 (5%) Frame = +3 Query: 99 ATKRAYKLQ--EFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLT 272 A KR + + + H S V C KF + L TG +Q N++ V + +L Sbjct: 297 ACKRVFNINLVHTLEHPSVVCCVKFSNN-GKYLATGC-NQAANVFDVQTGKKLFTLHE-E 353 Query: 273 SP-------VESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPF 431 SP V +++F + G IK+WD+ KV F+GH + SLD Sbjct: 354 SPDPSRDLYVRTIAFSPDGKYLVTGTEDRQIKLWDLSTQKVRYVFSGHEQDIYSLDFSHN 413 Query: 432 GDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 G F SGS D ++WD+ +CI + G + + +P+ ++I G D ++ Sbjct: 414 GRFIVSGSGDRTARLWDVETGQCILKLEIENG-VTAIAISPNDQFIAVGSLDQIIR 468 Score = 43.9 bits (102), Expect = 4e-04 Identities = 30/114 (26%), Positives = 55/114 (48%), Gaps = 12/114 (10%) Frame = +3 Query: 180 SRTLITGGEDQKVNLW------AVG----KPTAVL--SLSGLTSPVESLSFDSSEVMIGA 323 S L++G D+ + +W +VG KP + + +G T V S++ + Sbjct: 496 SSILLSGSLDKTIKVWELQATRSVGLSAIKPEGICKATYTGHTDFVLSVAVSPDSRWGLS 555 Query: 324 GAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDM 485 G+ +++ WD++ + T GH+++ S+ P G FASGS D +IW + Sbjct: 556 GSKDRSMQFWDLQTGQSYLTCQGHKNSVISVCFSPDGRQFASGSGDLRARIWSI 609
>GBB1_BRARE (Q6PH57) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 340 Score = 73.2 bits (178), Expect = 5e-13 Identities = 41/157 (26%), Positives = 76/157 (48%), Gaps = 2/157 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 +E H ++C +F ++T D LW + + +G T V SLS Sbjct: 137 RELAGHTGYLSCCRF--LDDNQIVTSSGDTTCALWDIETGQQTTTFAGHTGDVMSLSLAP 194 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 + +GA + K+WD+ E +TFTGH S+ ++ P G+ FA+GS D +++D Sbjct: 195 DTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFD 254 Query: 483 MR--KKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGAD 587 +R ++ ++++ I + F+ GR +++G D Sbjct: 255 LRADQELMVYSHDNIICGITSVAFSKSGRLLLAGYDD 291 Score = 69.3 bits (168), Expect = 8e-12 Identities = 36/115 (31%), Positives = 59/115 (51%), Gaps = 1/115 (0%) Frame = +3 Query: 258 LSGLTSPVESLSF-DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFG 434 L+G T + F D ++++ +G T +WDIE + TF GH + SL P Sbjct: 139 LAGHTGYLSCCRFLDDNQIVTSSGDT--TCALWDIETGQQTTTFAGHTGDVMSLSLAPDT 196 Query: 435 DFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 F SG+ D + K+WD+R+ C T+ GH I+ + F P+G +G D++ + Sbjct: 197 RLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCR 251 Score = 42.0 bits (97), Expect = 0.001 Identities = 31/122 (25%), Positives = 50/122 (40%), Gaps = 2/122 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAV--GKPTAVLSLSGLTSPVESLSF 296 Q F H SD+ F TG +D L+ + + V S + + S++F Sbjct: 220 QTFTGHESDINAICFFPN-GNAFATGSDDATCRLFDLRADQELMVYSHDNIICGITSVAF 278 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 S ++ AG +WD +A GH + + L G A+GS D+ +KI Sbjct: 279 SKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKI 338 Query: 477 WD 482 W+ Sbjct: 339 WN 340 Score = 32.7 bits (73), Expect = 0.82 Identities = 16/71 (22%), Positives = 27/71 (38%) Frame = +3 Query: 378 RTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPD 557 RT GH + ++ S S D + IWD +H + + + P Sbjct: 49 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPS 108 Query: 558 GRWIVSGGADS 590 G ++ GG D+ Sbjct: 109 GNYVACGGLDN 119
>PRP4_MOUSE (Q9DAW6) U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60| kDa protein) (WD splicing factor Prp4) Length = 521 Score = 73.2 bits (178), Expect = 5e-13 Identities = 36/142 (25%), Positives = 67/142 (47%), Gaps = 1/142 (0%) Frame = +3 Query: 177 TSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWD 356 + R L T D+ LW + +L G + V ++F + G G ++WD Sbjct: 333 SGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWD 392 Query: 357 IEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRID 536 + + + GH ++ P G A+GS D K+WD+R++RC++T H + Sbjct: 393 LRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVT 452 Query: 537 VLRFTP-DGRWIVSGGADSSVK 599 ++F P G ++++G D++ K Sbjct: 453 GVKFEPIHGDFLLTGAYDNTAK 474 Score = 67.0 bits (162), Expect = 4e-11 Identities = 35/131 (26%), Positives = 59/131 (45%) Frame = +3 Query: 207 DQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTF 386 D V LW++ V + G T V + + S +G + ++WD+E + + Sbjct: 301 DGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQ 360 Query: 387 TGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRW 566 GH + H G +G D ++WD+R RCI +GH I + F+P+G Sbjct: 361 EGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYH 420 Query: 567 IVSGGADSSVK 599 I +G D++ K Sbjct: 421 IATGSGDNTCK 431 Score = 65.9 bits (159), Expect = 9e-11 Identities = 36/136 (26%), Positives = 61/136 (44%), Gaps = 1/136 (0%) Frame = +3 Query: 195 TGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKV 374 TGG D +W + ++ L G + ++F + I G+ T K+WD+ + + Sbjct: 381 TGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRC 440 Query: 375 VRTFTGHRSNCASLDSHPF-GDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFT 551 V T H++ + P GDF +G+ D KIW + T GH G++ L + Sbjct: 441 VYTIPAHQNLVTGVKFEPIHGDFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDIS 500 Query: 552 PDGRWIVSGGADSSVK 599 DG+ I + D + K Sbjct: 501 SDGQLIATCSYDRTFK 516 Score = 61.6 bits (148), Expect = 2e-09 Identities = 37/145 (25%), Positives = 67/145 (46%), Gaps = 8/145 (5%) Frame = +3 Query: 180 SRTLITGGEDQKVNLWAVGKPTAVLSLSGLTS--------PVESLSFDSSEVMIGAGAAS 335 S+ L T LW+V + + +L G + P ++S D +V + + AA Sbjct: 242 SKMLATACWSGLCKLWSVPDCSLLHTLRGHNTNVGAIVFHPKSTVSLDQKDVNLASCAAD 301 Query: 336 GTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQ 515 G++K+W ++ + V GH A + HP G F + D + ++WD+ + I + Sbjct: 302 GSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQE 361 Query: 516 GHTGRIDVLRFTPDGRWIVSGGADS 590 GH+ + + F DG +GG D+ Sbjct: 362 GHSMGVYDIAFHQDGSLAGTGGLDA 386 Score = 53.1 bits (126), Expect = 6e-07 Identities = 25/106 (23%), Positives = 49/106 (46%), Gaps = 8/106 (7%) Frame = +3 Query: 276 PVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDF----- 440 P+ F + M+ SG K+W + + ++ T GH +N ++ HP Sbjct: 232 PISYCHFSPNSKMLATACWSGLCKLWSVPDCSLLHTLRGHNTNVGAIVFHPKSTVSLDQK 291 Query: 441 ---FASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWI 569 AS ++D ++K+W + + +GHT R+ + + P GR++ Sbjct: 292 DVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFL 337 Score = 38.5 bits (88), Expect = 0.015 Identities = 24/98 (24%), Positives = 38/98 (38%), Gaps = 1/98 (1%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEV-MIGAGAASGTIKIWDIEE 365 + TG D +W + + V ++ + V + F+ + GA T KIW Sbjct: 421 IATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGDFLLTGAYDNTAKIWTHPG 480 Query: 366 AKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 ++T GH LD G A+ S D K+W Sbjct: 481 WSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 518 Score = 32.0 bits (71), Expect = 1.4 Identities = 21/76 (27%), Positives = 31/76 (40%) Frame = +3 Query: 135 AHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVM 314 AH + VT KF L+TG D +W + + +L+G V L S + Sbjct: 446 AHQNLVTGVKFEPIHGDFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQL 505 Query: 315 IGAGAASGTIKIWDIE 362 I + T K+W E Sbjct: 506 IATCSYDRTFKLWMAE 521
>POF1_SCHPO (P87053) F-box/WD-repeat protein pof1 (Skp1-binding protein 1)| Length = 605 Score = 72.8 bits (177), Expect = 7e-13 Identities = 52/173 (30%), Positives = 80/173 (46%), Gaps = 6/173 (3%) Frame = +3 Query: 99 ATKRAYKLQEFV------AHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSL 260 AT R + L F H+S VTC +F + LI+G D+ + +W + L Sbjct: 293 ATIRLWNLATFQQVALLEGHSSGVTCLQFDQCK---LISGSMDKTIRIWNYRTSECISIL 349 Query: 261 SGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDF 440 G T V L+FDS+ ++ +G+A T+K+W K + T GH S+ Sbjct: 350 HGHTDSVLCLTFDST--LLVSGSADCTVKLWHFSGGKRI-TLRGHTGPVNSVRIIRDRGL 406 Query: 441 FASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 SGS D+ +KIW + C+HT+ H G + L D R + S D ++K Sbjct: 407 VLSGSDDSTIKIWSLETNTCLHTFSAHIGPVQSLALA-DSR-LFSCSLDGTIK 457 Score = 71.6 bits (174), Expect = 2e-12 Identities = 52/157 (33%), Positives = 70/157 (44%), Gaps = 3/157 (1%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMI 317 H V C F S L++G D V LW + +L G T PV S+ ++ Sbjct: 352 HTDSVLCLTFD---STLLVSGSADCTVKLWHFSGGKRI-TLRGHTGPVNSVRIIRDRGLV 407 Query: 318 GAGAASGTIKIWDIEEAKVVRTFTGHRSNCASL---DSHPFGDFFASGSSDTNMKIWDMR 488 +G+ TIKIW +E + TF+ H SL DS F S S D +K WD+ Sbjct: 408 LSGSDDSTIKIWSLETNTCLHTFSAHIGPVQSLALADSRLF-----SCSLDGTIKQWDIE 462 Query: 489 KKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 KK+C+HT GH V D ++SG D VK Sbjct: 463 KKKCVHTLFGHIE--GVWEIAADHLRLISGAHDGVVK 497 Score = 68.6 bits (166), Expect = 1e-11 Identities = 45/156 (28%), Positives = 76/156 (48%), Gaps = 2/156 (1%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMI 317 H+ V C + + L +G D + LW + V L G +S V L FD +++ Sbjct: 272 HSDGVMCLQLVRNI---LASGSYDATIRLWNLATFQQVALLEGHSSGVTCLQFDQCKLI- 327 Query: 318 GAGAASGTIKIWDIEEAKVVRTFTGHRSN--CASLDSHPFGDFFASGSSDTNMKIWDMRK 491 +G+ TI+IW+ ++ + GH + C + DS SGS+D +K+W Sbjct: 328 -SGSMDKTIRIWNYRTSECISILHGHTDSVLCLTFDS----TLLVSGSADCTVKLWHFSG 382 Query: 492 KRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 + I T +GHTG ++ +R D ++SG DS++K Sbjct: 383 GKRI-TLRGHTGPVNSVRIIRDRGLVLSGSDDSTIK 417
>GBB1_XENLA (P79959) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) (XGbeta1) Length = 340 Score = 72.8 bits (177), Expect = 7e-13 Identities = 42/157 (26%), Positives = 75/157 (47%), Gaps = 2/157 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 +E H ++C +F +IT D LW + + +G T V SLS Sbjct: 137 RELAGHTGYLSCCRF--LDDNQIITSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAP 194 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 +GA + K+WD+ E +TFTGH S+ ++ P G+ FA+GS D +++D Sbjct: 195 DSRCFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFD 254 Query: 483 MR--KKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGAD 587 +R ++ ++++ I + F+ GR +++G D Sbjct: 255 LRADQELMVYSHDNIICGITSVAFSKSGRLLLAGYDD 291 Score = 71.2 bits (173), Expect = 2e-12 Identities = 37/115 (32%), Positives = 60/115 (52%), Gaps = 1/115 (0%) Frame = +3 Query: 258 LSGLTSPVESLSF-DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFG 434 L+G T + F D ++++ +G T +WDIE + TFTGH + SL P Sbjct: 139 LAGHTGYLSCCRFLDDNQIITSSGDT--TCALWDIETGQQTTTFTGHTGDVMSLSLAPDS 196 Query: 435 DFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 F SG+ D + K+WD+R+ C T+ GH I+ + F P+G +G D++ + Sbjct: 197 RCFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCR 251 Score = 42.0 bits (97), Expect = 0.001 Identities = 31/122 (25%), Positives = 50/122 (40%), Gaps = 2/122 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAV--GKPTAVLSLSGLTSPVESLSF 296 Q F H SD+ F TG +D L+ + + V S + + S++F Sbjct: 220 QTFTGHESDINAICFFPN-GNAFATGSDDATCRLFDLRADQELMVYSHDNIICGITSVAF 278 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 S ++ AG +WD +A GH + + L G A+GS D+ +KI Sbjct: 279 SKSGRLLLAGYDDFNCNVWDTLKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKI 338 Query: 477 WD 482 W+ Sbjct: 339 WN 340 Score = 32.7 bits (73), Expect = 0.82 Identities = 16/71 (22%), Positives = 27/71 (38%) Frame = +3 Query: 378 RTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPD 557 RT GH + ++ S S D + IWD +H + + + P Sbjct: 49 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPS 108 Query: 558 GRWIVSGGADS 590 G ++ GG D+ Sbjct: 109 GNYVACGGLDN 119
>TAF73_SCHPO (O74319) Transcription initiation factor TFIID subunit taf73| (Transcription initiation factor TFIID 73 kDa subunit) (TAFII-73) Length = 642 Score = 72.4 bits (176), Expect = 9e-13 Identities = 32/137 (23%), Positives = 63/137 (45%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 +++ ED LW+ + ++ +G +P+ + F + T ++WD+E A Sbjct: 418 ILSCSEDGFTRLWSKDTKSTIVKYAGHNAPIWDVQFSPFGYYFATASHDQTARLWDVEHA 477 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 +R F GH+++ + HP + A+GSSD ++WD+R + + H + L Sbjct: 478 APLRVFVGHQNDVDCVSFHPNAAYLATGSSDHTTRMWDVRTGGTVRVFNAHHSPVSALCM 537 Query: 549 TPDGRWIVSGGADSSVK 599 + DG + S +K Sbjct: 538 SADGLSLASADESGIIK 554 Score = 70.1 bits (170), Expect = 5e-12 Identities = 38/134 (28%), Positives = 62/134 (46%) Frame = +3 Query: 195 TGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKV 374 T DQ LW V + G + V+ +SF + + G++ T ++WD+ Sbjct: 462 TASHDQTARLWDVEHAAPLRVFVGHQNDVDCVSFHPNAAYLATGSSDHTTRMWDVRTGGT 521 Query: 375 VRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTP 554 VR F H S ++L G AS +K+WD+R ++ H+ + L F+ Sbjct: 522 VRVFNAHHSPVSALCMSADGLSLASADESGIIKVWDLRSSNQHVSFVKHSSIVYSLSFSY 581 Query: 555 DGRWIVSGGADSSV 596 D + +VSGGAD+ V Sbjct: 582 DNKILVSGGADTDV 595 Score = 66.2 bits (160), Expect = 7e-11 Identities = 40/164 (24%), Positives = 73/164 (44%), Gaps = 12/164 (7%) Frame = +3 Query: 144 SDVTCAKFGKRTSRTLITGGEDQKVNLWA---------VG---KPTAVLSLSGLTSPVES 287 S V CA F S + G D ++L++ VG +P SL G T PV Sbjct: 350 SAVNCAAFSDDASMFAL-GCADSSIHLYSSTNNGPQPLVGSQNEPLQKSSLIGHTRPVFG 408 Query: 288 LSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTN 467 +S + I + + G ++W + + + GH + + PFG +FA+ S D Sbjct: 409 VSISPQKEFILSCSEDGFTRLWSKDTKSTIVKYAGHNAPIWDVQFSPFGYYFATASHDQT 468 Query: 468 MKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 ++WD+ + + GH +D + F P+ ++ +G +D + + Sbjct: 469 ARLWDVEHAAPLRVFVGHQNDVDCVSFHPNAAYLATGSSDHTTR 512 Score = 64.7 bits (156), Expect = 2e-10 Identities = 37/127 (29%), Positives = 56/127 (44%) Frame = +3 Query: 105 KRAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVE 284 + A L+ FV H +DV C F + L TG D +W V V + SPV Sbjct: 475 EHAAPLRVFVGHQNDVDCVSFHPNAAY-LATGSSDHTTRMWDVRTGGTVRVFNAHHSPVS 533 Query: 285 SLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDT 464 +L + + + + SG IK+WD+ + +F H S SL SG +DT Sbjct: 534 ALCMSADGLSLASADESGIIKVWDLRSSNQHVSFVKHSSIVYSLSFSYDNKILVSGGADT 593 Query: 465 NMKIWDM 485 ++ WD+ Sbjct: 594 DVNFWDL 600
>FBW1A_HUMAN (Q9Y297) F-box/WD-repeat protein 1A (F-box and WD-repeats protein| beta-TrCP) (E3RSIkappaB) (pIkappaBalpha-E3 receptor subunit) Length = 605 Score = 72.0 bits (175), Expect = 1e-12 Identities = 45/163 (27%), Positives = 75/163 (46%), Gaps = 3/163 (1%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLS---LSGLTSPVESL 290 L + H V +F + ++T +D+ + +W + PT + L G + V + Sbjct: 376 LNTLIHHCEAVLHLRFN---NGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVV 432 Query: 291 SFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNM 470 FD ++ +G TIK+W+ + VRT GH+ A L SGSSD + Sbjct: 433 DFDDKYIVSASG--DRTIKVWNTSTCEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTI 488 Query: 471 KIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 ++WD+ C+ +GH + +RF D + IVSG D +K Sbjct: 489 RLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGAYDGKIK 529 Score = 44.7 bits (104), Expect = 2e-04 Identities = 27/92 (29%), Positives = 43/92 (46%), Gaps = 2/92 (2%) Frame = +3 Query: 279 VESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSN--CASLDSHPFGDFFASG 452 V L +D +++ +G TIKIWD + R TGH + C D +G Sbjct: 306 VYCLQYDDQKIV--SGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDER----VIITG 359 Query: 453 SSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 SSD+ +++WD+ ++T H + LRF Sbjct: 360 SSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRF 391 Score = 44.3 bits (103), Expect = 3e-04 Identities = 31/124 (25%), Positives = 49/124 (39%), Gaps = 9/124 (7%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMI 317 H + C ++ R +++G D + LW + + L G V + FD+ ++ Sbjct: 465 HKRGIACLQY---RDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIV- 520 Query: 318 GAGAASGTIKIWDIEEA---------KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNM 470 +GA G IK+WD+ A +RT H L F S S D + Sbjct: 521 -SGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQ--IVSSSHDDTI 577 Query: 471 KIWD 482 IWD Sbjct: 578 LIWD 581 Score = 40.8 bits (94), Expect = 0.003 Identities = 20/51 (39%), Positives = 29/51 (56%) Frame = +3 Query: 447 SGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 SG D +KIWD C GHTG + L++ D R I++G +DS+V+ Sbjct: 318 SGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQY--DERVIITGSSDSTVR 366
>A16L1_HUMAN (Q676U5) Autophagy-related protein 16-1 (APG16-like 1)| Length = 607 Score = 72.0 bits (175), Expect = 1e-12 Identities = 44/129 (34%), Positives = 63/129 (48%), Gaps = 2/129 (1%) Frame = +3 Query: 129 FVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVL--SLSGLTSPVESLSFDS 302 F AH +V +F SR L TGG D++V LW V SLSG + + S+ FDS Sbjct: 318 FDAHDGEVNAVQFSPG-SRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDS 376 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 + + A + +IW +++ ++ T TGH S SGS D +K+WD Sbjct: 377 AGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWD 436 Query: 483 MRKKRCIHT 509 +R K CI T Sbjct: 437 LRSKVCIKT 445 Score = 55.5 bits (132), Expect = 1e-07 Identities = 29/121 (23%), Positives = 56/121 (46%), Gaps = 2/121 (1%) Frame = +3 Query: 243 TAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDI--EEAKVVRTFTGHRSNCASL 416 TA+ V ++ F ++ G +K+W++ E+ + + +G + S+ Sbjct: 313 TALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSI 372 Query: 417 DSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 + G + + S+D +IW + R HT GH+G++ +F D IVSG D ++ Sbjct: 373 EFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTL 432 Query: 597 K 599 K Sbjct: 433 K 433 Score = 48.1 bits (113), Expect = 2e-05 Identities = 44/174 (25%), Positives = 78/174 (44%), Gaps = 5/174 (2%) Frame = +3 Query: 90 SRMATKRAYKLQE-FVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSG 266 SR+ T Y+L+ H+ V AKF +R +++G D+ + LW + + ++ Sbjct: 390 SRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNAR-IVSGSHDRTLKLWDLRSKVCIKTVFA 448 Query: 267 LTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFA 446 +S + + +E + +G I+ WDI +VR +LD +P Sbjct: 449 GSSCNDIVC---TEQCVMSGHFDKKIRFWDIRSESIVREME-LLGKITALDLNPERTELL 504 Query: 447 SGSSDTNMKIWDMRKKRCIHTYQ--GHTGRIDVLR--FTPDGRWIVSGGADSSV 596 S S D +K+ D+R T+ G D R F+PDG ++ +G A+ S+ Sbjct: 505 SCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSL 558
>AAMP_PONPY (Q5RCG7) Angio-associated migratory cell protein| Length = 434 Score = 72.0 bits (175), Expect = 1e-12 Identities = 39/157 (24%), Positives = 69/157 (43%) Frame = +3 Query: 129 FVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSE 308 F H++ V C +T+ +TGGED K +W + + +G V F Sbjct: 87 FALHSASVFCVSLDPKTNTLAVTGGEDDKAFVWRLSDGELLFECAGHKDSVTCAGFSHDS 146 Query: 309 VMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMR 488 ++ G SG +K+W ++ + V +F + ++ HP +G++D N +W + Sbjct: 147 TLVATGDMSGLLKVWQVDTKEEVWSF--EAGDLEWMEWHPRAPVLLAGTADGNTWMWKVP 204 Query: 489 KKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 C T+QG R PDG+ V G D +++ Sbjct: 205 NGDC-KTFQGPNCPATCGRVLPDGKRAVVGYEDGTIR 240 Score = 45.4 bits (106), Expect = 1e-04 Identities = 43/169 (25%), Positives = 68/169 (40%), Gaps = 15/169 (8%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWA--------VGKPTAVLSLSGL-------T 272 H +TC + S ++TG D + L + V +P V S L + Sbjct: 259 HQGPLTCVATNQDGS-LILTGSVDCQAKLVSATTGKVVGVFRPETVASQPSLGEGEESES 317 Query: 273 SPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASG 452 + VESL F S + G GT+ I+D+ + +R H+S L + Sbjct: 318 NSVESLGFCSVMPLAAVGYLDGTLAIYDLA-TQTLRHQCQHQSGIVQLLWEAGTAVVYTC 376 Query: 453 SSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 S D +++WD R R + Y+GHT I + D +V+ D K Sbjct: 377 SLDGIVRLWDARTGRLLTDYRGHTAEILDFALSKDASLVVTTSGDHKAK 425
>AAMP_HUMAN (Q13685) Angio-associated migratory cell protein| Length = 434 Score = 72.0 bits (175), Expect = 1e-12 Identities = 39/157 (24%), Positives = 69/157 (43%) Frame = +3 Query: 129 FVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSE 308 F H++ V C +T+ +TGGED K +W + + +G V F Sbjct: 87 FALHSASVFCVSLDPKTNTLAVTGGEDDKAFVWRLSDGELLFECAGHKDSVTCAGFSHDS 146 Query: 309 VMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMR 488 ++ G SG +K+W ++ + V +F + ++ HP +G++D N +W + Sbjct: 147 TLVATGDMSGLLKVWQVDTKEEVWSF--EAGDLEWMEWHPRAPVLLAGTADGNTWMWKVP 204 Query: 489 KKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 C T+QG R PDG+ V G D +++ Sbjct: 205 NGDC-KTFQGPNCPATCGRVLPDGKRAVVGYEDGTIR 240 Score = 45.4 bits (106), Expect = 1e-04 Identities = 43/169 (25%), Positives = 68/169 (40%), Gaps = 15/169 (8%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWA--------VGKPTAVLSLSGL-------T 272 H +TC + S ++TG D + L + V +P V S L + Sbjct: 259 HQGPLTCVAANQDGS-LILTGSVDCQAKLVSATTGKVVGVFRPETVASQPSLGEGEESES 317 Query: 273 SPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASG 452 + VESL F S + G GT+ I+D+ + +R H+S L + Sbjct: 318 NSVESLGFCSVMPLAAVGYLDGTLAIYDLA-TQTLRHQCQHQSGIVQLLWEAGTAVVYTC 376 Query: 453 SSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 S D +++WD R R + Y+GHT I + D +V+ D K Sbjct: 377 SLDGIVRLWDARTGRLLTDYRGHTAEILDFALSKDASLVVTTSGDHKAK 425
>AAMP_CANFA (Q7YR70) Angio-associated migratory cell protein| Length = 435 Score = 72.0 bits (175), Expect = 1e-12 Identities = 39/157 (24%), Positives = 69/157 (43%) Frame = +3 Query: 129 FVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSE 308 F H++ V C +T+ +TGGED K +W + + +G V F Sbjct: 88 FALHSASVFCVSLDPKTNTLAVTGGEDDKAFVWRLSDGELLFECAGHKDSVTCAGFSHDS 147 Query: 309 VMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMR 488 ++ G SG +K+W ++ + V +F + ++ HP +G++D N +W + Sbjct: 148 TLVATGDMSGLLKVWQVDTKEEVWSF--EAGDLEWMEWHPRAPVLLAGTADGNTWMWKVP 205 Query: 489 KKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 C T+QG R PDG+ V G D +++ Sbjct: 206 NGDC-KTFQGPNCPATCGRVLPDGKRAVVGYEDGTIR 241 Score = 44.7 bits (104), Expect = 2e-04 Identities = 42/169 (24%), Positives = 68/169 (40%), Gaps = 15/169 (8%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWA--------VGKPTAVLSLSGL-------T 272 H +TC + S ++TG D + L + V +P V S + + Sbjct: 260 HQGPLTCVATNQDGS-LILTGSVDCQAQLVSATTGKVVGVFRPETVASQPNVGEGEESES 318 Query: 273 SPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASG 452 + VESL F S + G GT+ I+D+ + +R H+S L + Sbjct: 319 NSVESLGFCSVMPLAAVGYLDGTLAIYDLS-TQTLRHQCQHQSGIVQLLWEAGTAVVYTC 377 Query: 453 SSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 S D +++WD R R + Y+GHT I + D +V+ D K Sbjct: 378 SLDGIVRLWDARTGRLLTDYRGHTAEILDFALSKDASLVVTTSGDHKAK 426
>LIN23_CAEEL (Q09990) F-box/WD-repeat protein lin-23 (Abnormal cell lineage| protein 23) Length = 665 Score = 72.0 bits (175), Expect = 1e-12 Identities = 42/140 (30%), Positives = 69/140 (49%), Gaps = 3/140 (2%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLS---LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDI 359 ++T +D+ + +W + P + L G + V + FD ++ +G TIK+W + Sbjct: 315 MVTCSKDRSIAVWDMVSPRDITIRRVLVGHRAAVNVVDFDDRYIVSASG--DRTIKVWSM 372 Query: 360 EEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDV 539 + + VRT GHR A L G SGSSD +++WD+ C+ +GH + Sbjct: 373 DTLEFVRTLAGHRRGIACLQYR--GRLVVSGSSDNTIRLWDIHSGVCLRVLEGHEELVRC 430 Query: 540 LRFTPDGRWIVSGGADSSVK 599 +RF D + IVSG D +K Sbjct: 431 IRF--DEKRIVSGAYDGKIK 448 Score = 50.8 bits (120), Expect = 3e-06 Identities = 35/114 (30%), Positives = 52/114 (45%), Gaps = 4/114 (3%) Frame = +3 Query: 219 NLWAVG--KPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTG 392 N W G K T + S + V L +D +++ +G TIKIWD ++ R +G Sbjct: 203 NNWKRGNYKMTRINCQSENSKGVYCLQYDDDKIV--SGLRDNTIKIWDRKDYSCSRILSG 260 Query: 393 HRSN--CASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 H + C D+ SGSSD +++WD+ CI T H + LRF Sbjct: 261 HTGSVLCLQYDNR----VIISGSSDATVRVWDVETGECIKTLIHHCEAVLHLRF 310 Score = 50.1 bits (118), Expect = 5e-06 Identities = 34/129 (26%), Positives = 54/129 (41%), Gaps = 8/129 (6%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 ++ H + C ++ R +++G D + LW + + L G V + FD Sbjct: 378 VRTLAGHRRGIACLQY---RGRLVVSGSSDNTIRLWDIHSGVCLRVLEGHEELVRCIRFD 434 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSH-------PFGDF-FASGS 455 ++ +GA G IK+WD++ A R + C SL H F DF S S Sbjct: 435 EKRIV--SGAYDGKIKVWDLQAALDPRALSSEICLC-SLVQHTGRVFRLQFDDFQIVSSS 491 Query: 456 SDTNMKIWD 482 D + IWD Sbjct: 492 HDDTILIWD 500 Score = 44.3 bits (103), Expect = 3e-04 Identities = 26/74 (35%), Positives = 37/74 (50%), Gaps = 6/74 (8%) Frame = +3 Query: 396 RSNCASLDSHPF------GDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPD 557 R NC S +S D SG D +KIWD + C GHTG + L++ D Sbjct: 214 RINCQSENSKGVYCLQYDDDKIVSGLRDNTIKIWDRKDYSCSRILSGHTGSVLCLQY--D 271 Query: 558 GRWIVSGGADSSVK 599 R I+SG +D++V+ Sbjct: 272 NRVIISGSSDATVR 285
>A16L1_MOUSE (Q8C0J2) Autophagy-related protein 16-1 (APG16-like 1)| Length = 607 Score = 71.6 bits (174), Expect = 2e-12 Identities = 44/129 (34%), Positives = 63/129 (48%), Gaps = 2/129 (1%) Frame = +3 Query: 129 FVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAV--GKPTAVLSLSGLTSPVESLSFDS 302 F AH +V +F SR L TGG D++V LW K SLSG + + S+ FDS Sbjct: 318 FDAHDGEVNAVQFSPG-SRLLATGGMDRRVKLWEAFGDKCEFKGSLSGSNAGITSIEFDS 376 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 + + A + +IW +++ ++ T TGH S SGS D +K+WD Sbjct: 377 AGAYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWD 436 Query: 483 MRKKRCIHT 509 +R K CI T Sbjct: 437 LRSKVCIKT 445 Score = 51.6 bits (122), Expect = 2e-06 Identities = 44/177 (24%), Positives = 76/177 (42%), Gaps = 7/177 (3%) Frame = +3 Query: 90 SRMATKRAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGL 269 SR ATKR L + D FG+R S + I +D A GK V + + Sbjct: 261 SRAATKR---LSQPAGGLLDSITNIFGRR-SVSSIPVPQDIMDTHPASGKDVRVPTTASY 316 Query: 270 T-----SPVESLSFDSSEVMIGAGAASGTIKIWDI--EEAKVVRTFTGHRSNCASLDSHP 428 V ++ F ++ G +K+W+ ++ + + +G + S++ Sbjct: 317 VFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEAFGDKCEFKGSLSGSNAGITSIEFDS 376 Query: 429 FGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 G + + S+D +IW + R HT GH+G++ +F D IVSG D ++K Sbjct: 377 AGAYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLK 433 Score = 48.5 bits (114), Expect = 1e-05 Identities = 45/174 (25%), Positives = 78/174 (44%), Gaps = 5/174 (2%) Frame = +3 Query: 90 SRMATKRAYKLQE-FVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSG 266 SR+ T Y+L+ H+ V AKF +R +++G D+ + LW + + ++ Sbjct: 390 SRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNAR-IVSGSHDRTLKLWDLRSKVCIKTVFA 448 Query: 267 LTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFA 446 +S + + +E + +G I+ WDI VVR +LD +P Sbjct: 449 GSSCNDIVC---TEQCVMSGHFDKKIRFWDIRSESVVREME-LLGKITALDLNPERTELL 504 Query: 447 SGSSDTNMKIWDMRKKRCIHTYQ--GHTGRIDVLR--FTPDGRWIVSGGADSSV 596 S S D +K+ D+R T+ G D R F+PDG ++ +G A+ S+ Sbjct: 505 SCSRDDLLKVIDLRTNAVKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSL 558
>PRP46_KLULA (Q6CKE8) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 434 Score = 71.6 bits (174), Expect = 2e-12 Identities = 39/163 (23%), Positives = 71/163 (43%), Gaps = 1/163 (0%) Frame = +3 Query: 114 YKLQEFV-AHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESL 290 +KL + + H V C + TG D + +W + ++L G V + Sbjct: 112 WKLSKVINGHTGWVRCVCVDPVDNEWFATGSNDTTIKIWDLAAGKLKITLIGHVMSVRDI 171 Query: 291 SFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNM 470 + + + + +K WD+E +R F GH S ++D HP D A+ D + Sbjct: 172 AISKRHPYMFSASEDKLVKCWDLERNTAIRDFHGHLSGVHTVDVHPSLDIIATAGRDAVV 231 Query: 471 KIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 ++WD+R + I GH I+ ++ P I+S D++V+ Sbjct: 232 RLWDIRSRSEIMVLPGHKSPINKVKCLPVDPQIISCSGDATVR 274 Score = 55.8 bits (133), Expect = 9e-08 Identities = 34/137 (24%), Positives = 67/137 (48%), Gaps = 1/137 (0%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 + T G D V LW + + ++ L G SP+ + + I + + T+++WDI Sbjct: 222 IATAGRDAVVRLWDIRSRSEIMVLPGHKSPINKVKCLPVDPQIISCSGDATVRLWDIIAG 281 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQG-HTGRIDVLR 545 K + T H N L HP FAS S++ +++ W + + + + +Q +TG ++ + Sbjct: 282 KASKVLTHHSRNIRDLTLHPAEFSFASVSTN-DVRSWKLPEGQLLTNFQSQNTGILNTVS 340 Query: 546 FTPDGRWIVSGGADSSV 596 D +++GG D ++ Sbjct: 341 INHD-NVLLAGGDDGTL 356 Score = 49.7 bits (117), Expect = 6e-06 Identities = 31/141 (21%), Positives = 53/141 (37%) Frame = +3 Query: 132 VAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEV 311 + H V KR + + ED+ V W + + TA+ G S V ++ S Sbjct: 162 IGHVMSVRDIAISKRHPY-MFSASEDKLVKCWDLERNTAIRDFHGHLSGVHTVDVHPSLD 220 Query: 312 MIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRK 491 +I +++WDI + GH+S + P S S D +++WD+ Sbjct: 221 IIATAGRDAVVRLWDIRSRSEIMVLPGHKSPINKVKCLPVDPQIISCSGDATVRLWDIIA 280 Query: 492 KRCIHTYQGHTGRIDVLRFTP 554 + H+ I L P Sbjct: 281 GKASKVLTHHSRNIRDLTLHP 301
>APAF_MOUSE (O88879) Apoptotic protease-activating factor 1 (Apaf-1)| Length = 1249 Score = 71.6 bits (174), Expect = 2e-12 Identities = 43/156 (27%), Positives = 73/156 (46%), Gaps = 2/156 (1%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMI 317 H V A F + R + + G D+ + ++ +L + V +F S + I Sbjct: 614 HTDAVYHACFSQDGQR-IASCGADKTLQVFKAETGEKLLDIKAHEDEVLCCAFSSDDSYI 672 Query: 318 GAGAASGTIKIWDIEEAKVVRTFTGHRS--NCASLDSHPFGDFFASGSSDTNMKIWDMRK 491 +A +KIWD K+V T+ H NC + A+GS+D +K+WD+ + Sbjct: 673 ATCSADKKVKIWDSATGKLVHTYDEHSEQVNCCHFTNSSNHLLLATGSNDFFLKLWDLNQ 732 Query: 492 KRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 K C +T GHT ++ RF+PD + S AD +++ Sbjct: 733 KECRNTMFGHTNSVNHCRFSPDDELLASCSADGTLR 768 Score = 53.9 bits (128), Expect = 3e-07 Identities = 32/126 (25%), Positives = 57/126 (45%), Gaps = 2/126 (1%) Frame = +3 Query: 117 KLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSF 296 KL + AH +V C F S + T D+KV +W V + + V F Sbjct: 649 KLLDIKAHEDEVLCCAFSSDDSY-IATCSADKKVKIWDSATGKLVHTYDEHSEQVNCCHF 707 Query: 297 --DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNM 470 S+ +++ G+ +K+WD+ + + T GH ++ P + AS S+D + Sbjct: 708 TNSSNHLLLATGSNDFFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDELLASCSADGTL 767 Query: 471 KIWDMR 488 ++WD+R Sbjct: 768 RLWDVR 773 Score = 53.5 bits (127), Expect = 4e-07 Identities = 32/139 (23%), Positives = 61/139 (43%) Frame = +3 Query: 183 RTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIE 362 +TLI+ ED + +W V + + + S ++ + + GT+K+W++ Sbjct: 1016 KTLISSSEDSVIQVWNWQTGDYVFLQAHQETVKDFRLLQDSRLL--SWSFDGTVKVWNVI 1073 Query: 363 EAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVL 542 ++ R FT H+ S F+S S+D KIW +H +GH G + Sbjct: 1074 TGRIERDFTCHQGTVLSCAISSDATKFSSTSADKTAKIWSFDLLSPLHELKGHNGCVRCS 1133 Query: 543 RFTPDGRWIVSGGADSSVK 599 F+ DG + +G + ++ Sbjct: 1134 AFSLDGILLATGDDNGEIR 1152 Score = 46.6 bits (109), Expect = 5e-05 Identities = 36/210 (17%), Positives = 75/210 (35%), Gaps = 56/210 (26%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLI-TGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVM 314 H+ V C F ++ L+ TG D + LW + + ++ G T+ V F + + Sbjct: 698 HSEQVNCCHFTNSSNHLLLATGSNDFFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDEL 757 Query: 315 IGAGAASGTIKIWDI----------------------EEAKVV----------------- 377 + + +A GT+++WD+ E+ +V+ Sbjct: 758 LASCSADGTLRLWDVRSANERKSINVKRFFLSSEDPPEDVEVIVKCCSWSADGDKIIVAA 817 Query: 378 ----------------RTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHT 509 TGH S D P+ S +++W++ + + Sbjct: 818 KNKVLLFDIHTSGLLAEIHTGHHSTIQYCDFSPYDHLAVIALSQYCVELWNIDSRLKVAD 877 Query: 510 YQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 +GH + + F+PDG ++ D +++ Sbjct: 878 CRGHLSWVHGVMFSPDGSSFLTASDDQTIR 907 Score = 38.9 bits (89), Expect = 0.011 Identities = 33/144 (22%), Positives = 57/144 (39%), Gaps = 13/144 (9%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L++ D V +W V + V S + S + +A T KIW + Sbjct: 1058 LLSWSFDGTVKVWNVITGRIERDFTCHQGTVLSCAISSDATKFSSTSADKTAKIWSFDLL 1117 Query: 369 KVVRTFTGH----RSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQG------ 518 + GH R + SLD G A+G + ++IW++ + +H+ Sbjct: 1118 SPLHELKGHNGCVRCSAFSLD----GILLATGDDNGEIRIWNVSDGQLLHSCAPISVEEG 1173 Query: 519 ---HTGRIDVLRFTPDGRWIVSGG 581 H G + + F+PD + +VS G Sbjct: 1174 TATHGGWVTDVCFSPDSKTLVSAG 1197 Score = 38.9 bits (89), Expect = 0.011 Identities = 32/146 (21%), Positives = 63/146 (43%), Gaps = 8/146 (5%) Frame = +3 Query: 186 TLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVE-SLSFDSSEVMIGAGAASGTIKIWDIE 362 + +T +DQ + +W K V S + E + F +E M+ + + +I Sbjct: 896 SFLTASDDQTIRVWETKK---VCKNSAIVLKQEIDVVFQENETMV--------LAVDNIR 944 Query: 363 EAKVVRTFTGH-------RSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGH 521 +++ TG + +C L H ++ A G D +KI ++ R + GH Sbjct: 945 GLQLIAGKTGQIDYLPEAQVSCCCLSPHL--EYVAFGDEDGAIKIIELPNNRVFSSGVGH 1002 Query: 522 TGRIDVLRFTPDGRWIVSGGADSSVK 599 + ++FT DG+ ++S DS ++ Sbjct: 1003 KKAVRHIQFTADGKTLISSSEDSVIQ 1028 Score = 32.3 bits (72), Expect = 1.1 Identities = 16/77 (20%), Positives = 34/77 (44%) Frame = +3 Query: 261 SGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDF 440 +G S ++ F + + + +++W+I+ V GH S + P G Sbjct: 837 TGHHSTIQYCDFSPYDHLAVIALSQYCVELWNIDSRLKVADCRGHLSWVHGVMFSPDGSS 896 Query: 441 FASGSSDTNMKIWDMRK 491 F + S D +++W+ +K Sbjct: 897 FLTASDDQTIRVWETKK 913 Score = 32.0 bits (71), Expect = 1.4 Identities = 28/120 (23%), Positives = 50/120 (41%) Frame = +3 Query: 240 PTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLD 419 P A +S L+ +E ++F G G IKI ++ +V + GH+ + Sbjct: 960 PEAQVSCCCLSPHLEYVAF---------GDEDGAIKIIELPNNRVFSSGVGHKKAVRHIQ 1010 Query: 420 SHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 G S S D+ +++W+ + + Q H + R D R ++S D +VK Sbjct: 1011 FTADGKTLISSSEDSVIQVWNWQTGDYVF-LQAHQETVKDFRLLQDSR-LLSWSFDGTVK 1068
>GBB3_RAT (P52287) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 3 (Transducin beta chain 3) Length = 340 Score = 71.6 bits (174), Expect = 2e-12 Identities = 42/139 (30%), Positives = 67/139 (48%), Gaps = 5/139 (3%) Frame = +3 Query: 198 GGEDQKVNLWAV----GKPTAVLSLSGLTSPVESLSF-DSSEVMIGAGAASGTIKIWDIE 362 GG D +++++ G LS T + F D + ++ +G T +WDIE Sbjct: 115 GGLDNMCSIYSLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDT--TCALWDIE 172 Query: 363 EAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVL 542 + F GH +C SL P F SG+ D + K+WD+R+ C T+ GH I+ + Sbjct: 173 TGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREGTCRQTFTGHESDINAI 232 Query: 543 RFTPDGRWIVSGGADSSVK 599 F P+G I +G D+S + Sbjct: 233 CFFPNGEAICTGSDDASCR 251 Score = 62.8 bits (151), Expect = 7e-10 Identities = 38/157 (24%), Positives = 72/157 (45%), Gaps = 2/157 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 +E AH ++C +F ++T D LW + G T SL+ Sbjct: 137 RELSAHTGYLSCCRF--LDDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSP 194 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 + +GA + K+WD+ E +TFTGH S+ ++ P G+ +GS D + +++D Sbjct: 195 DYKLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFD 254 Query: 483 MR--KKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGAD 587 +R ++ ++++ I + F+ GR + +G D Sbjct: 255 LRADQELTAYSHESIICGITSVAFSLSGRLLFAGYDD 291 Score = 42.4 bits (98), Expect = 0.001 Identities = 30/122 (24%), Positives = 53/122 (43%), Gaps = 2/122 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLS--GLTSPVESLSF 296 Q F H SD+ F + TG +D L+ + + + S + + S++F Sbjct: 220 QTFTGHESDINAICFFPN-GEAICTGSDDASCRLFDLRADQELTAYSHESIICGITSVAF 278 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 S ++ AG +WD + + V +GH + + L G A+GS D+ +KI Sbjct: 279 SLSGRLLFAGYDDFNCNVWDSLKCERVGVLSGHDNRVSCLGVTADGMAVATGSWDSFLKI 338 Query: 477 WD 482 W+ Sbjct: 339 WN 340 Score = 32.3 bits (72), Expect = 1.1 Identities = 15/71 (21%), Positives = 27/71 (38%) Frame = +3 Query: 378 RTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPD 557 RT GH + ++ S S D + +WD +H + + + P Sbjct: 49 RTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAPS 108 Query: 558 GRWIVSGGADS 590 G ++ GG D+ Sbjct: 109 GNFVACGGLDN 119
>GBB3_CANFA (P79147) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 3 (Transducin beta chain 3) Length = 340 Score = 71.6 bits (174), Expect = 2e-12 Identities = 42/139 (30%), Positives = 67/139 (48%), Gaps = 5/139 (3%) Frame = +3 Query: 198 GGEDQKVNLWAV----GKPTAVLSLSGLTSPVESLSF-DSSEVMIGAGAASGTIKIWDIE 362 GG D +++++ G LS T + F D + ++ +G T +WDIE Sbjct: 115 GGLDNMCSIYSLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDT--TCALWDIE 172 Query: 363 EAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVL 542 + F GH +C SL P F SG+ D + K+WD+R+ C T+ GH I+ + Sbjct: 173 TGQQKTVFVGHTGDCMSLAVSPDFKLFISGACDASAKLWDVREGTCRQTFTGHESDINAI 232 Query: 543 RFTPDGRWIVSGGADSSVK 599 F P+G I +G D+S + Sbjct: 233 CFFPNGEAICTGSDDASCR 251 Score = 62.8 bits (151), Expect = 7e-10 Identities = 39/157 (24%), Positives = 70/157 (44%), Gaps = 2/157 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 +E AH ++C +F ++T D LW + G T SL+ Sbjct: 137 RELSAHTGYLSCCRF--LDDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSP 194 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 + +GA + K+WD+ E +TFTGH S+ ++ P G+ +GS D + +++D Sbjct: 195 DFKLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFD 254 Query: 483 MRKKRCIHTYQGHT--GRIDVLRFTPDGRWIVSGGAD 587 +R + + Y + I + F+ GR + +G D Sbjct: 255 LRADQELTAYSDESIICGITSVAFSLSGRLLFAGYDD 291 Score = 42.4 bits (98), Expect = 0.001 Identities = 30/122 (24%), Positives = 53/122 (43%), Gaps = 2/122 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLS--GLTSPVESLSF 296 Q F H SD+ F + TG +D L+ + + + S + + S++F Sbjct: 220 QTFTGHESDINAICFFPN-GEAICTGSDDASCRLFDLRADQELTAYSDESIICGITSVAF 278 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 S ++ AG IWD + + V +GH + + L G A+GS D+ +K+ Sbjct: 279 SLSGRLLFAGYDDFNCNIWDSMKGERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKV 338 Query: 477 WD 482 W+ Sbjct: 339 WN 340 Score = 32.3 bits (72), Expect = 1.1 Identities = 15/71 (21%), Positives = 27/71 (38%) Frame = +3 Query: 378 RTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPD 557 RT GH + ++ S S D + +WD +H + + + P Sbjct: 49 RTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAPS 108 Query: 558 GRWIVSGGADS 590 G ++ GG D+ Sbjct: 109 GNFVACGGLDN 119
>A16L1_PONPY (Q5RAC9) Autophagy-related protein 16-1 (APG16-like 1)| Length = 607 Score = 71.2 bits (173), Expect = 2e-12 Identities = 44/129 (34%), Positives = 63/129 (48%), Gaps = 2/129 (1%) Frame = +3 Query: 129 FVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVL--SLSGLTSPVESLSFDS 302 F AH +V +F SR L TGG D++V LW V SLSG + + S+ FDS Sbjct: 318 FDAHDGEVNAVQFSPG-SRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDS 376 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 + + A + +IW ++++++ T TGH S SGS D +K WD Sbjct: 377 AGSYLLAASNDFASRIWTVDDSRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKHWD 436 Query: 483 MRKKRCIHT 509 +R K CI T Sbjct: 437 LRSKVCIKT 445 Score = 56.2 bits (134), Expect = 7e-08 Identities = 29/121 (23%), Positives = 56/121 (46%), Gaps = 2/121 (1%) Frame = +3 Query: 243 TAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDI--EEAKVVRTFTGHRSNCASL 416 TA+ V ++ F ++ G +K+W++ E+ + + +G + S+ Sbjct: 313 TALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSI 372 Query: 417 DSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 + G + + S+D +IW + R HT GH+G++ +F D IVSG D ++ Sbjct: 373 EFDSAGSYLLAASNDFASRIWTVDDSRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTL 432 Query: 597 K 599 K Sbjct: 433 K 433 Score = 42.4 bits (98), Expect = 0.001 Identities = 38/157 (24%), Positives = 69/157 (43%), Gaps = 4/157 (2%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMI 317 H+ V AKF +R +++G D+ + W + + ++ +S + + +E + Sbjct: 407 HSGKVLSAKFLLDNAR-IVSGSHDRTLKHWDLRSKVCIKTVFAGSSCNDIVC---TEQCV 462 Query: 318 GAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKR 497 +G I+ WDI +VR +LD +P S S D +K+ D+R Sbjct: 463 MSGHFDKKIRFWDIRSESIVREME-LLGKITALDLNPERTELLSCSRDDLLKVIDLRTNA 521 Query: 498 CIHTYQ--GHTGRIDVLR--FTPDGRWIVSGGADSSV 596 T+ G D R F+PDG ++ +G A+ S+ Sbjct: 522 IKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSL 558
>APAF_RAT (Q9EPV5) Apoptotic protease-activating factor 1 (Apaf-1)| Length = 1249 Score = 71.2 bits (173), Expect = 2e-12 Identities = 43/156 (27%), Positives = 72/156 (46%), Gaps = 2/156 (1%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMI 317 H V A F + R + + G D+ + ++ +L + V +F S + I Sbjct: 614 HTDAVYHACFSQDGQR-IASCGADKTLQVFKAETGEKLLDIKAHEDEVLCCAFSSDDSYI 672 Query: 318 GAGAASGTIKIWDIEEAKVVRTFTGHRS--NCASLDSHPFGDFFASGSSDTNMKIWDMRK 491 + +KIWD K+V T+ H NC + A+GS+D+ +K+WD+ + Sbjct: 673 ATCSVDKKVKIWDSGTGKLVHTYEEHSEQVNCCHFTNKSNHLLLATGSNDSFLKLWDLNQ 732 Query: 492 KRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 K C +T GHT + RF+PD + S AD ++K Sbjct: 733 KECRNTMFGHTNSVTHCRFSPDDELLASCSADGTLK 768 Score = 58.5 bits (140), Expect = 1e-08 Identities = 34/126 (26%), Positives = 58/126 (46%), Gaps = 2/126 (1%) Frame = +3 Query: 117 KLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSF 296 KL + AH +V C F S + T D+KV +W G V + + V F Sbjct: 649 KLLDIKAHEDEVLCCAFSSDDSY-IATCSVDKKVKIWDSGTGKLVHTYEEHSEQVNCCHF 707 Query: 297 D--SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNM 470 S+ +++ G+ +K+WD+ + + T GH ++ P + AS S+D + Sbjct: 708 TNKSNHLLLATGSNDSFLKLWDLNQKECRNTMFGHTNSVTHCRFSPDDELLASCSADGTL 767 Query: 471 KIWDMR 488 K+WD+R Sbjct: 768 KLWDVR 773 Score = 52.0 bits (123), Expect = 1e-06 Identities = 31/139 (22%), Positives = 60/139 (43%) Frame = +3 Query: 183 RTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIE 362 +TLI+ ED + +W V + + + S ++ + + GT+K+W++ Sbjct: 1016 KTLISSSEDSVIQVWNWQTEEYVFLQAHQETVKDFRLLRDSRLL--SWSFDGTVKVWNVI 1073 Query: 363 EAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVL 542 ++ R FT H+ S F+S S+D KIW +H +GH + Sbjct: 1074 TGRIERDFTCHQGTVLSCAISSDATKFSSTSADKTAKIWSFELPSPLHELKGHNSCVRCS 1133 Query: 543 RFTPDGRWIVSGGADSSVK 599 F+ DG + +G + ++ Sbjct: 1134 AFSLDGILLATGDDNGEIR 1152 Score = 49.3 bits (116), Expect = 8e-06 Identities = 37/210 (17%), Positives = 76/210 (36%), Gaps = 56/210 (26%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLI-TGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVM 314 H+ V C F +++ L+ TG D + LW + + ++ G T+ V F + + Sbjct: 698 HSEQVNCCHFTNKSNHLLLATGSNDSFLKLWDLNQKECRNTMFGHTNSVTHCRFSPDDEL 757 Query: 315 IGAGAASGTIKIWDI----------------------EEAKVV----------------- 377 + + +A GT+K+WD+ E+ +V+ Sbjct: 758 LASCSADGTLKLWDVRSANEKKSINVKRFFLSSEDPPEDVEVIVKCCSWSADGDRIIVAA 817 Query: 378 ----------------RTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHT 509 TGH S D P+ S +++W++ + + Sbjct: 818 KNKVLLLDIHTSGLLTEIHTGHHSTIQYCDFSPYDHLAVIALSQYCVELWNIDSRVKVAD 877 Query: 510 YQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 +GH + + F+PDG ++ D +++ Sbjct: 878 CRGHLSWVHGVMFSPDGSSFLTASDDQTIR 907 Score = 40.0 bits (92), Expect = 0.005 Identities = 39/170 (22%), Positives = 65/170 (38%), Gaps = 14/170 (8%) Frame = +3 Query: 114 YKLQEFV-AHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESL 290 ++ +E+V A T F L++ D V +W V + V S Sbjct: 1032 WQTEEYVFLQAHQETVKDFRLLRDSRLLSWSFDGTVKVWNVITGRIERDFTCHQGTVLSC 1091 Query: 291 SFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRS----NCASLDSHPFGDFFASGSS 458 + S + +A T KIW E + GH S + SLD G A+G Sbjct: 1092 AISSDATKFSSTSADKTAKIWSFELPSPLHELKGHNSCVRCSAFSLD----GILLATGDD 1147 Query: 459 DTNMKIWDMRKKRCIHTYQG---------HTGRIDVLRFTPDGRWIVSGG 581 + ++IW++ + +H H G + + F+PD + +VS G Sbjct: 1148 NGEIRIWNVSDGQLLHLCAPISIEEGTATHGGWVTDVCFSPDRKMLVSAG 1197 Score = 37.4 bits (85), Expect = 0.033 Identities = 31/146 (21%), Positives = 64/146 (43%), Gaps = 8/146 (5%) Frame = +3 Query: 186 TLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVE-SLSFDSSEVMIGAGAASGTIKIWDIE 362 + +T +DQ + +W K V S + E + F +E+M+ + + +I Sbjct: 896 SFLTASDDQTIRVWETRK---VCKNSAIVLKQEIDVVFQENEMMV--------LAVDNIR 944 Query: 363 EAKVVRTFTGH-------RSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGH 521 +++ TG + +C L H ++ A G + +KI ++ R + GH Sbjct: 945 GLQLIAGKTGQIDYLPEAQVSCCCLSPHL--EYVAFGDEEGAIKIIELPNNRVFSSGIGH 1002 Query: 522 TGRIDVLRFTPDGRWIVSGGADSSVK 599 + ++FT DG+ ++S DS ++ Sbjct: 1003 KKAVRHIQFTADGKTLISSSEDSVIQ 1028 Score = 33.5 bits (75), Expect = 0.48 Identities = 28/120 (23%), Positives = 51/120 (42%) Frame = +3 Query: 240 PTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLD 419 P A +S L+ +E ++F E G IKI ++ +V + GH+ + Sbjct: 960 PEAQVSCCCLSPHLEYVAFGDEE---------GAIKIIELPNNRVFSSGIGHKKAVRHIQ 1010 Query: 420 SHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 G S S D+ +++W+ + + + Q H + R D R ++S D +VK Sbjct: 1011 FTADGKTLISSSEDSVIQVWNWQTEEYVF-LQAHQETVKDFRLLRDSR-LLSWSFDGTVK 1068 Score = 33.5 bits (75), Expect = 0.48 Identities = 17/77 (22%), Positives = 34/77 (44%) Frame = +3 Query: 261 SGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDF 440 +G S ++ F + + + +++W+I+ V GH S + P G Sbjct: 837 TGHHSTIQYCDFSPYDHLAVIALSQYCVELWNIDSRVKVADCRGHLSWVHGVMFSPDGSS 896 Query: 441 FASGSSDTNMKIWDMRK 491 F + S D +++W+ RK Sbjct: 897 FLTASDDQTIRVWETRK 913
>GBB3_HUMAN (P16520) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 3 (Transducin beta chain 3) Length = 340 Score = 71.2 bits (173), Expect = 2e-12 Identities = 34/101 (33%), Positives = 54/101 (53%) Frame = +3 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 D + ++ +G T +WDIE + F GH +C SL P + F SG+ D + K+ Sbjct: 153 DDNNIVTSSGDT--TCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKL 210 Query: 477 WDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 WD+R+ C T+ GH I+ + F P+G I +G D+S + Sbjct: 211 WDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCR 251 Score = 61.6 bits (148), Expect = 2e-09 Identities = 45/203 (22%), Positives = 70/203 (34%), Gaps = 44/203 (21%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 +E AH ++C +F ++T D LW + G T SL+ Sbjct: 137 RELSAHTGYLSCCRF--LDDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSP 194 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDT------ 464 + +GA + K+WD+ E +TFTGH S+ ++ P G+ +GS D Sbjct: 195 DFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFD 254 Query: 465 --------------------------------------NMKIWDMRKKRCIHTYQGHTGR 530 N +WD K + GH R Sbjct: 255 LRADQELICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNR 314 Query: 531 IDVLRFTPDGRWIVSGGADSSVK 599 + L T DG + +G DS +K Sbjct: 315 VSCLGVTADGMAVATGSWDSFLK 337 Score = 43.5 bits (101), Expect = 5e-04 Identities = 30/122 (24%), Positives = 54/122 (44%), Gaps = 2/122 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLS--GLTSPVESLSF 296 Q F H SD+ F + TG +D L+ + ++ S + + S++F Sbjct: 220 QTFTGHESDINAICFFPN-GEAICTGSDDASCRLFDLRADQELICFSHESIICGITSVAF 278 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 S ++ AG +WD +++ V +GH + + L G A+GS D+ +KI Sbjct: 279 SLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKI 338 Query: 477 WD 482 W+ Sbjct: 339 WN 340 Score = 32.3 bits (72), Expect = 1.1 Identities = 15/71 (21%), Positives = 27/71 (38%) Frame = +3 Query: 378 RTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPD 557 RT GH + ++ S S D + +WD +H + + + P Sbjct: 49 RTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPS 108 Query: 558 GRWIVSGGADS 590 G ++ GG D+ Sbjct: 109 GNFVACGGLDN 119
>PRP19_HUMAN (Q9UMS4) Pre-mRNA-splicing factor 19 (PRP19/PSO4 homolog) (Nuclear| matrix protein 200) (hPso4) Length = 504 Score = 70.9 bits (172), Expect = 3e-12 Identities = 42/181 (23%), Positives = 76/181 (41%), Gaps = 44/181 (24%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 ++TGG D+ V ++ + +L G T V S+ F S+ ++ + + TI+IW + A Sbjct: 237 ILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIWSVPNA 296 Query: 369 KVVRTFTGHRSNCASLDSHPFGDF------------------------------------ 440 V+ H S L H GD+ Sbjct: 297 SCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCA 356 Query: 441 --------FASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 F +G+ D+ +KIWD++++ + + GH+G I + F+ +G ++ + DSSV Sbjct: 357 QFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSV 416 Query: 597 K 599 K Sbjct: 417 K 417 Score = 61.2 bits (147), Expect = 2e-09 Identities = 44/160 (27%), Positives = 68/160 (42%), Gaps = 6/160 (3%) Frame = +3 Query: 135 AHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLS-----FD 299 AH S VT T L++ +DQ WA L+ +T S F Sbjct: 304 AHESAVTGLSL-HATGDYLLSSSDDQ---YWAFSDIQTGRVLTKVTDETSGCSLTCAQFH 359 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 ++ G G IKIWD++E V F GH S+ G + A+ + D+++K+W Sbjct: 360 PDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLW 419 Query: 480 DMRKKRCIHTYQ-GHTGRIDVLRFTPDGRWIVSGGADSSV 596 D+RK + T Q + + L F G ++ GG D + Sbjct: 420 DLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTDVQI 459
>GBB3_MOUSE (Q61011) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 3 (Transducin beta chain 3) Length = 340 Score = 70.5 bits (171), Expect = 4e-12 Identities = 34/101 (33%), Positives = 53/101 (52%) Frame = +3 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 D + ++ +G T +WDIE + F GH +C SL P F SG+ D + K+ Sbjct: 153 DDNNIVTSSGDT--TCALWDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKL 210 Query: 477 WDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 WD+R+ C T+ GH I+ + F P+G I +G D+S + Sbjct: 211 WDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCR 251 Score = 62.8 bits (151), Expect = 7e-10 Identities = 39/157 (24%), Positives = 70/157 (44%), Gaps = 2/157 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 +E AH ++C +F ++T D LW + G T SL+ Sbjct: 137 RELSAHTGYLSCCRF--LDDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSP 194 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 + +GA + K+WD+ E +TFTGH S+ ++ P G+ +GS D + +++D Sbjct: 195 DYKLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFD 254 Query: 483 MRKKRCIHTYQGHT--GRIDVLRFTPDGRWIVSGGAD 587 +R + + Y + I + F+ GR + +G D Sbjct: 255 LRADQELTAYSQESIICGITSVAFSLSGRLLFAGYDD 291 Score = 42.4 bits (98), Expect = 0.001 Identities = 30/122 (24%), Positives = 52/122 (42%), Gaps = 2/122 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAV--GKPTAVLSLSGLTSPVESLSF 296 Q F H SD+ F + TG +D L+ + + S + + S++F Sbjct: 220 QTFTGHESDINAICFFPN-GEAICTGSDDASCRLFDLRADQELTAYSQESIICGITSVAF 278 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 S ++ AG +WD + + V +GH + + L G A+GS D+ +KI Sbjct: 279 SLSGRLLFAGYDDFNCNVWDSLKCERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKI 338 Query: 477 WD 482 W+ Sbjct: 339 WN 340 Score = 32.3 bits (72), Expect = 1.1 Identities = 15/71 (21%), Positives = 27/71 (38%) Frame = +3 Query: 378 RTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPD 557 RT GH + ++ S S D + +WD +H + + + P Sbjct: 49 RTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAPS 108 Query: 558 GRWIVSGGADS 590 G ++ GG D+ Sbjct: 109 GNFVACGGLDN 119
>YCW2_YEAST (P25382) Hypothetical WD-repeat protein YCR072C| Length = 515 Score = 70.1 bits (170), Expect = 5e-12 Identities = 44/162 (27%), Positives = 71/162 (43%), Gaps = 8/162 (4%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMI 317 H S + C+ F TS ++TG D +W T + +L G + V +S+ +I Sbjct: 142 HGSTILCSAFAPHTSSRMVTGAGDNTARIWDCDTQTPMHTLKGHYNWVLCVSWSPDGEVI 201 Query: 318 GAGAASGTIKIWDIEEAKVV-RTFTGHRSNCASLDSHPF-------GDFFASGSSDTNMK 473 G+ TI++WD + + + GH SL P AS S D +K Sbjct: 202 ATGSMDNTIRLWDPKSGQCLGDALRGHSKWITSLSWEPIHLVKPGSKPRLASSSKDGTIK 261 Query: 474 IWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 IWD + C +T GHT + +++ G + SG D +V+ Sbjct: 262 IWDTVSRVCQYTMSGHTNSVSCVKWGGQG-LLYSGSHDRTVR 302 Score = 66.6 bits (161), Expect = 5e-11 Identities = 39/149 (26%), Positives = 71/149 (47%), Gaps = 1/149 (0%) Frame = +3 Query: 156 CAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLS-LSGLTSPVESLSFDSSEVMIGAGAA 332 C K G + ++T +D + LW K T ++ ++G V ++F I + + Sbjct: 364 CKKNGN-SEEMMVTASDDYTMFLWNPLKSTKPIARMTGHQKLVNHVAFSPDGRYIVSASF 422 Query: 333 SGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTY 512 +IK+WD + K + TF GH ++ + S S DT +K+WD+R ++ Sbjct: 423 DNSIKLWDGRDGKFISTFRGHVASVYQVAWSSDCRLLVSCSKDTTLKVWDVRTRKLSVDL 482 Query: 513 QGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 GH + + ++ DG+ + SGG D V+ Sbjct: 483 PGHKDEVYTVDWSVDGKRVCSGGKDKMVR 511 Score = 40.8 bits (94), Expect = 0.003 Identities = 20/99 (20%), Positives = 44/99 (44%) Frame = +3 Query: 183 RTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIE 362 R +++ D + LW + + G + V +++ S ++ + + T+K+WD+ Sbjct: 415 RYIVSASFDNSIKLWDGRDGKFISTFRGHVASVYQVAWSSDCRLLVSCSKDTTLKVWDVR 474 Query: 363 EAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 K+ GH+ ++D G SG D +++W Sbjct: 475 TRKLSVDLPGHKDEVYTVDWSVDGKRVCSGGKDKMVRLW 513
>GBB4_HUMAN (Q9HAV0) Guanine nucleotide-binding protein beta subunit 4| (Transducin beta chain 4) Length = 339 Score = 70.1 bits (170), Expect = 5e-12 Identities = 34/101 (33%), Positives = 54/101 (53%) Frame = +3 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 D S+++ +G T +WDIE A+ TFTGH + SL P F SG+ D + K+ Sbjct: 152 DDSQIVTSSGDT--TCALWDIETAQQTTTFTGHSGDVMSLSLSPDMRTFVSGACDASSKL 209 Query: 477 WDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 WD+R C ++ GH I+ + F P+G +G D++ + Sbjct: 210 WDIRDGMCRQSFTGHVSDINAVSFFPNGYAFATGSDDATCR 250 Score = 65.1 bits (157), Expect = 1e-10 Identities = 39/157 (24%), Positives = 74/157 (47%), Gaps = 2/157 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 +E H ++C +F ++T D LW + + +G + V SLS Sbjct: 136 RELPGHTGYLSCCRF--LDDSQIVTSSGDTTCALWDIETAQQTTTFTGHSGDVMSLSLSP 193 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 +GA + K+WDI + ++FTGH S+ ++ P G FA+GS D +++D Sbjct: 194 DMRTFVSGACDASSKLWDIRDGMCRQSFTGHVSDINAVSFFPNGYAFATGSDDATCRLFD 253 Query: 483 MR--KKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGAD 587 +R ++ ++++ I + F+ GR +++G D Sbjct: 254 LRADQELLLYSHDNIICGITSVAFSKSGRLLLAGYDD 290 Score = 40.4 bits (93), Expect = 0.004 Identities = 29/122 (23%), Positives = 49/122 (40%), Gaps = 2/122 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLS--GLTSPVESLSF 296 Q F H SD+ F TG +D L+ + +L S + + S++F Sbjct: 219 QSFTGHVSDINAVSFFPN-GYAFATGSDDATCRLFDLRADQELLLYSHDNIICGITSVAF 277 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 S ++ AG +WD + GH + + L G A+GS D+ ++I Sbjct: 278 SKSGRLLLAGYDDFNCNVWDTLKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRI 337 Query: 477 WD 482 W+ Sbjct: 338 WN 339 Score = 31.2 bits (69), Expect = 2.4 Identities = 16/71 (22%), Positives = 27/71 (38%) Frame = +3 Query: 378 RTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPD 557 RT GH + ++ S S D + IWD +H + + + P Sbjct: 48 RTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPS 107 Query: 558 GRWIVSGGADS 590 G ++ GG D+ Sbjct: 108 GNYVACGGLDN 118
>LEUNG_ARATH (Q9FUY2) Transcriptional corepressor LEUNIG| Length = 931 Score = 70.1 bits (170), Expect = 5e-12 Identities = 42/154 (27%), Positives = 72/154 (46%), Gaps = 3/154 (1%) Frame = +3 Query: 135 AHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVM 314 A + VTC F + L + G D+K LW +L T+ + + F S++ Sbjct: 649 ASTTKVTCCHFSS-DGKMLASAGHDKKAVLWYTDTMKPKTTLEEHTAMITDIRFSPSQLR 707 Query: 315 IGAGAASGTIKIWDIE-EAKVVRTFTGHRSNCASLDSHPF-GDFFASGSSDTNMKIWDMR 488 + + T+++WD + + +RTF GH S SLD HP D S +D ++ W + Sbjct: 708 LATSSFDKTVRVWDADNKGYSLRTFMGHSSMVTSLDFHPIKDDLICSCDNDNEIRYWSIN 767 Query: 489 KKRCIHTYQGHTGRIDVLRFTPD-GRWIVSGGAD 587 C Y+G + +I RF P G+++ + A+ Sbjct: 768 NGSCTRVYKGGSTQI---RFQPRVGKYLAASSAN 798 Score = 48.9 bits (115), Expect = 1e-05 Identities = 33/155 (21%), Positives = 64/155 (41%), Gaps = 3/155 (1%) Frame = +3 Query: 99 ATKRAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSP 278 A + Y L+ F+ H+S VT F + + D ++ W++ + G ++ Sbjct: 722 ADNKGYSLRTFMGHSSMVTSLDFHPIKDDLICSCDNDNEIRYWSINNGSCTRVYKGGSTQ 781 Query: 279 VESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSS 458 + F A +++ + + D+E + + GH + S+ P GDF AS S Sbjct: 782 IR---FQPRVGKYLAASSANLVNVLDVETQAIRHSLQGHANPINSVCWDPSGDFLASVSE 838 Query: 459 DTNMKIWDM---RKKRCIHTYQGHTGRIDVLRFTP 554 D +K+W + + C+H + + F P Sbjct: 839 DM-VKVWTLGTGSEGECVHELSCNGNKFQSCVFHP 872
>GBB1_DROME (P26308) Guanine nucleotide-binding protein beta subunit 1| Length = 340 Score = 69.7 bits (169), Expect = 6e-12 Identities = 42/157 (26%), Positives = 73/157 (46%), Gaps = 2/157 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 +E H ++C +F ++T D LW + V S G T V +LS Sbjct: 137 RELPGHGGYLSCCRF--LDDNQIVTSSGDMSCGLWDIETGLQVTSFLGHTGDVMALSLAP 194 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 +GA + K+WDI E +TF GH S+ ++ P G FA+GS D +++D Sbjct: 195 QCKTFVSGACDASAKLWDIREGVCKQTFPGHESDINAVTFFPNGQAFATGSDDATCRLFD 254 Query: 483 MR--KKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGAD 587 +R ++ ++++ I + F+ GR +++G D Sbjct: 255 IRADQELAMYSHDNIICGITSVAFSKSGRLLLAGYDD 291 Score = 63.9 bits (154), Expect = 3e-10 Identities = 31/101 (30%), Positives = 54/101 (53%) Frame = +3 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 D ++++ +G S +WDIE V +F GH + +L P F SG+ D + K+ Sbjct: 153 DDNQIVTSSGDMS--CGLWDIETGLQVTSFLGHTGDVMALSLAPQCKTFVSGACDASAKL 210 Query: 477 WDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 WD+R+ C T+ GH I+ + F P+G+ +G D++ + Sbjct: 211 WDIREGVCKQTFPGHESDINAVTFFPNGQAFATGSDDATCR 251 Score = 42.7 bits (99), Expect = 8e-04 Identities = 29/122 (23%), Positives = 53/122 (43%), Gaps = 2/122 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAV--GKPTAVLSLSGLTSPVESLSF 296 Q F H SD+ F + TG +D L+ + + A+ S + + S++F Sbjct: 220 QTFPGHESDINAVTFFPN-GQAFATGSDDATCRLFDIRADQELAMYSHDNIICGITSVAF 278 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 S ++ AG +WD +A+ GH + + L G A+GS D+ +++ Sbjct: 279 SKSGRLLLAGYDDFNCNVWDTMKAERSGILAGHDNRVSCLGVTENGMAVATGSWDSFLRV 338 Query: 477 WD 482 W+ Sbjct: 339 WN 340 Score = 31.2 bits (69), Expect = 2.4 Identities = 15/71 (21%), Positives = 27/71 (38%) Frame = +3 Query: 378 RTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPD 557 RT GH + ++ S S D + +WD +H + + + P Sbjct: 49 RTLRGHLAKIYAMHWGNDSRNLVSASQDGKLIVWDSHTTNKVHAIPLRSSWVMTCAYAPS 108 Query: 558 GRWIVSGGADS 590 G ++ GG D+ Sbjct: 109 GSYVACGGLDN 119
>PWP2_SCHPO (Q9C1X1) Periodic tryptophan protein 2 homolog| Length = 854 Score = 69.7 bits (169), Expect = 6e-12 Identities = 37/141 (26%), Positives = 72/141 (51%), Gaps = 4/141 (2%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 +ITG +D K+ +W + +++ + TS V L F ++ + + G+++ WD+ Sbjct: 354 IITGADDGKIKVWDMNSGFCIVTFTQHTSAVSGLCFSKRGNVLFSSSLDGSVRAWDLIRY 413 Query: 369 KVVRTFTGH---RSNCASLDSHPFGDFFASGSSDT-NMKIWDMRKKRCIHTYQGHTGRID 536 + RTFT + +C ++D P G+ +GS D+ + +W ++ + + T GH G + Sbjct: 414 RNFRTFTAPSRVQFSCIAVD--PSGEIVCAGSQDSFEIFMWSVQTGQLLETLAGHEGPVS 471 Query: 537 VLRFTPDGRWIVSGGADSSVK 599 L F G + SG D +V+ Sbjct: 472 SLSFNSSGSLLASGSWDKTVR 492 Score = 61.2 bits (147), Expect = 2e-09 Identities = 41/162 (25%), Positives = 72/162 (44%), Gaps = 1/162 (0%) Frame = +3 Query: 117 KLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSF 296 K + + S + CA F TS L+ G ++ + T + LS S +++L+ Sbjct: 246 KERHYFNQNSKLRCAAFHP-TSNLLVVGFSSGLFGIYELPSFTMLYQLSITQSNIDTLTV 304 Query: 297 DSSEVMIGAGAAS-GTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMK 473 +S+ I G++ G + +W+ + V H ++L G +G+ D +K Sbjct: 305 NSTGDWIAIGSSKLGQLLVWEWQSESYVLKQQSHYDALSTLQYSSDGQRIITGADDGKIK 364 Query: 474 IWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 +WDM CI T+ HT + L F+ G + S D SV+ Sbjct: 365 VWDMNSGFCIVTFTQHTSAVSGLCFSKRGNVLFSSSLDGSVR 406 Score = 51.6 bits (122), Expect = 2e-06 Identities = 32/124 (25%), Positives = 53/124 (42%), Gaps = 1/124 (0%) Frame = +3 Query: 222 LWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRS 401 +W + VL + +L + S I GA G IK+WD+ + TFT H S Sbjct: 323 VWEWQSESYVLKQQSHYDALSTLQYSSDGQRIITGADDGKIKVWDMNSGFCIVTFTQHTS 382 Query: 402 NCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTG-RIDVLRFTPDGRWIVSG 578 + L G+ S S D +++ WD+ + R T+ + + + P G + +G Sbjct: 383 AVSGLCFSKRGNVLFSSSLDGSVRAWDLIRYRNFRTFTAPSRVQFSCIAVDPSGEIVCAG 442 Query: 579 GADS 590 DS Sbjct: 443 SQDS 446
>LIS1_CAEEL (Q9NDC9) Lissencephaly-1 homolog (Pronuclear migration abnormal| protein 1) Length = 404 Score = 69.7 bits (169), Expect = 6e-12 Identities = 35/132 (26%), Positives = 65/132 (49%), Gaps = 1/132 (0%) Frame = +3 Query: 204 EDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA-KVVR 380 ED + +W +L G T V ++ D++ + + ++ +IK+WD + ++ Sbjct: 126 EDATIKVWDYETGQLERTLKGHTDAVNDIAIDAAGKQLVSCSSDLSIKLWDFGQTYDCLK 185 Query: 381 TFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDG 560 + GH +S+ P GDF S S D +K WD+ C++T++GH + ++R + DG Sbjct: 186 SLKGHEHTVSSVTFLPTGDFVLSASRDHTIKQWDISTGYCVYTFRGHNDWVRMIRISNDG 245 Query: 561 RWIVSGGADSSV 596 S D +V Sbjct: 246 TLFASASLDQTV 257 Score = 62.4 bits (150), Expect = 1e-09 Identities = 32/124 (25%), Positives = 59/124 (47%), Gaps = 1/124 (0%) Frame = +3 Query: 231 VGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCA 410 + +P L+G P+ + F ++ + + TIK+WD E ++ RT GH Sbjct: 93 IPRPPETQKLTGHRLPITRVIFHPLWTIMASCSEDATIKVWDYETGQLERTLKGHTDAVN 152 Query: 411 SLDSHPFGDFFASGSSDTNMKIWDM-RKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGAD 587 + G S SSD ++K+WD + C+ + +GH + + F P G +++S D Sbjct: 153 DIAIDAAGKQLVSCSSDLSIKLWDFGQTYDCLKSLKGHEHTVSSVTFLPTGDFVLSASRD 212 Query: 588 SSVK 599 ++K Sbjct: 213 HTIK 216 Score = 58.5 bits (140), Expect = 1e-08 Identities = 33/146 (22%), Positives = 63/146 (43%), Gaps = 15/146 (10%) Frame = +3 Query: 207 DQKVNLWAVGKPTAVLSLSGLTSPVESLSF---------------DSSEVMIGAGAASGT 341 DQ V +W+ +A L L VE + + +S ++ +G+ + Sbjct: 254 DQTVTVWSFATKSAKLVLRDHEHAVECVEWAPDTAYTNVTGQQPEGNSTHILFSGSRDRS 313 Query: 342 IKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGH 521 IK W+I V+ T H + L HP G + S + D +++W++ +RC+ + H Sbjct: 314 IKAWNINTGDVLFTLLAHENWVRGLAFHPKGKYLISVADDKTLRVWELSAQRCMKAIEAH 373 Query: 522 TGRIDVLRFTPDGRWIVSGGADSSVK 599 + + F ++++G D S K Sbjct: 374 EHFVSTVAFHQTSPFVITGSVDMSCK 399 Score = 53.9 bits (128), Expect = 3e-07 Identities = 34/126 (26%), Positives = 53/126 (42%), Gaps = 1/126 (0%) Frame = +3 Query: 183 RTLITGGEDQKVNLWAVGKPTAVL-SLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDI 359 + L++ D + LW G+ L SL G V S++F + + + + TIK WDI Sbjct: 161 KQLVSCSSDLSIKLWDFGQTYDCLKSLKGHEHTVSSVTFLPTGDFVLSASRDHTIKQWDI 220 Query: 360 EEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDV 539 V TF GH + G FAS S D + +W K + H ++ Sbjct: 221 STGYCVYTFRGHNDWVRMIRISNDGTLFASASLDQTVTVWSFATKSAKLVLRDHEHAVEC 280 Query: 540 LRFTPD 557 + + PD Sbjct: 281 VEWAPD 286 Score = 48.5 bits (114), Expect = 1e-05 Identities = 35/122 (28%), Positives = 51/122 (41%), Gaps = 1/122 (0%) Frame = +3 Query: 237 KPTAVLSLSGLTSPVES-LSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCAS 413 K T VL L + +ES L E+ GA I + TGHR Sbjct: 52 KWTTVLRLQRKVNDLESKLQESQREINHGAPTRDKRQAADWIPRPPETQKLTGHRLPITR 111 Query: 414 LDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSS 593 + HP AS S D +K+WD + T +GHT ++ + G+ +VS +D S Sbjct: 112 VIFHPLWTIMASCSEDATIKVWDYETGQLERTLKGHTDAVNDIAIDAAGKQLVSCSSDLS 171 Query: 594 VK 599 +K Sbjct: 172 IK 173
>GROU_DROME (P16371) Protein groucho (Enhancer of split m9/10 protein)| (E(spl)m9/10) Length = 719 Score = 69.7 bits (169), Expect = 6e-12 Identities = 38/141 (26%), Positives = 67/141 (47%), Gaps = 2/141 (1%) Frame = +3 Query: 183 RTLITGGEDQKVNLWAVGKPTAVLS--LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWD 356 RTLI GGE +++W + PT + L+ +L+ + + + G I +WD Sbjct: 492 RTLIVGGEASNLSIWDLASPTPRIKAELTSAAPACYALAISPDSKVCFSCCSDGNIAVWD 551 Query: 357 IEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRID 536 + +VR F GH + +D P G +G D ++ WD+R+ R + + + +I Sbjct: 552 LHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNTVRSWDLREGRQLQQHD-FSSQIF 610 Query: 537 VLRFTPDGRWIVSGGADSSVK 599 L + P G W+ G +S V+ Sbjct: 611 SLGYCPTGDWLAVGMENSHVE 631 Score = 54.7 bits (130), Expect = 2e-07 Identities = 37/158 (23%), Positives = 69/158 (43%), Gaps = 7/158 (4%) Frame = +3 Query: 147 DVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLT-----SPVESLSFDSSEV 311 +V CA ++ + TGG+ V +W + +P +S L + + S+ Sbjct: 434 EVVCAVTISNPTKYVYTGGKGC-VKVWDISQPGNKNPVSQLDCLQRDNYIRSVKLLPDGR 492 Query: 312 MIGAGAASGTIKIWDIEEA--KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDM 485 + G + + IWD+ ++ T C +L P S SD N+ +WD+ Sbjct: 493 TLIVGGEASNLSIWDLASPTPRIKAELTSAAPACYALAISPDSKVCFSCCSDGNIAVWDL 552 Query: 486 RKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 + + +QGHT + +PDG + +GG D++V+ Sbjct: 553 HNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNTVR 590
>TUP1_KLULA (P56094) Transcriptional repressor TUP1| Length = 682 Score = 69.3 bits (168), Expect = 8e-12 Identities = 37/122 (30%), Positives = 56/122 (45%) Frame = +3 Query: 234 GKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCAS 413 G + S + + S+ F + GA I+IWD+E K+V T GH + S Sbjct: 394 GNQNSAASTASSDLYIRSVCFSPDGKFLATGAEDKLIRIWDLETKKIVMTLKGHEQDIYS 453 Query: 414 LDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSS 593 LD P G+ SGS D ++IWD+ C T G V +G++I +G D + Sbjct: 454 LDYFPSGNKLVSGSGDRTVRIWDLTTGTCSLTLSIEDGVTTVAVSPGEGKFIAAGSLDRT 513 Query: 594 VK 599 V+ Sbjct: 514 VR 515 Score = 64.3 bits (155), Expect = 3e-10 Identities = 40/144 (27%), Positives = 64/144 (44%), Gaps = 7/144 (4%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L TG ED+ + +W + V++L G + SL + S + +G+ T++IWD+ Sbjct: 421 LATGAEDKLIRIWDLETKKIVMTLKGHEQDIYSLDYFPSGNKLVSGSGDRTVRIWDLTTG 480 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQ-------GHTG 527 T + S G F A+GS D +++WD + GH Sbjct: 481 TCSLTLSIEDGVTTVAVSPGEGKFIAAGSLDRTVRVWDSDTGFLVERLDSENELGTGHRD 540 Query: 528 RIDVLRFTPDGRWIVSGGADSSVK 599 + + FT DG+ +VSG D SVK Sbjct: 541 SVYSVVFTRDGKGVVSGSLDRSVK 564 Score = 42.7 bits (99), Expect = 8e-04 Identities = 29/120 (24%), Positives = 53/120 (44%), Gaps = 13/120 (10%) Frame = +3 Query: 174 RTSRTLITGGEDQKVNLWAVG-------KPTAVLSLSGLTSPVESLSFDSSEVMIGAGAA 332 R + +++G D+ V LW + ++ +G V S++ ++ I +G+ Sbjct: 549 RDGKGVVSGSLDRSVKLWNLNGLSGQKSHAECEVTYTGHKDFVLSVATTQNDEYILSGSK 608 Query: 333 SGTIKIWDIEEAKVVRTFTGHRSNCASL---DSHPFG---DFFASGSSDTNMKIWDMRKK 494 + WD + + GHR++ S+ + HP G FA+GS D +IW KK Sbjct: 609 DRGVLFWDTKSGNPLLMLQGHRNSVISVTVANGHPLGPEYGVFATGSGDCKARIWKYSKK 668 Score = 39.7 bits (91), Expect = 0.007 Identities = 30/142 (21%), Positives = 55/142 (38%), Gaps = 14/142 (9%) Frame = +3 Query: 150 VTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSL-------SGLTSPVESLSFDSSE 308 VT + + G D+ V +W V L +G V S+ F Sbjct: 492 VTTVAVSPGEGKFIAAGSLDRTVRVWDSDTGFLVERLDSENELGTGHRDSVYSVVFTRDG 551 Query: 309 VMIGAGAASGTIKIWDIE-------EAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTN 467 + +G+ ++K+W++ A+ T+TGH+ S+ + ++ SGS D Sbjct: 552 KGVVSGSLDRSVKLWNLNGLSGQKSHAECEVTYTGHKDFVLSVATTQNDEYILSGSKDRG 611 Query: 468 MKIWDMRKKRCIHTYQGHTGRI 533 + WD + + QGH + Sbjct: 612 VLFWDTKSGNPLLMLQGHRNSV 633
>PRP19_RAT (Q9JMJ4) Pre-mRNA-splicing factor 19 (PRP19/PSO4 homolog) (Neuronal| differentiation-related gene protein) Length = 504 Score = 69.3 bits (168), Expect = 8e-12 Identities = 41/181 (22%), Positives = 75/181 (41%), Gaps = 44/181 (24%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 ++TGG D+ V ++ + +L G T V S+ F S+ ++ + + TI+IW + Sbjct: 237 ILTGGADKNVVVFDKSTEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIRIWSVPNT 296 Query: 369 KVVRTFTGHRSNCASLDSHPFGDF------------------------------------ 440 V+ H S L H GD+ Sbjct: 297 SCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCA 356 Query: 441 --------FASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 F +G+ D+ +KIWD++++ + + GH+G I + F+ +G ++ + DSSV Sbjct: 357 QFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSV 416 Query: 597 K 599 K Sbjct: 417 K 417 Score = 61.2 bits (147), Expect = 2e-09 Identities = 44/160 (27%), Positives = 68/160 (42%), Gaps = 6/160 (3%) Frame = +3 Query: 135 AHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLS-----FD 299 AH S VT T L++ +DQ WA L+ +T S F Sbjct: 304 AHESAVTGLSL-HATGDYLLSSSDDQ---YWAFSDIQTGRVLTKVTDETSGCSLTCAQFH 359 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 ++ G G IKIWD++E V F GH S+ G + A+ + D+++K+W Sbjct: 360 PDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLW 419 Query: 480 DMRKKRCIHTYQ-GHTGRIDVLRFTPDGRWIVSGGADSSV 596 D+RK + T Q + + L F G ++ GG D + Sbjct: 420 DLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTDVQI 459
>PRP19_MOUSE (Q99KP6) Pre-mRNA-splicing factor 19 (PRP19/PSO4 homolog) (Nuclear| matrix protein 200) (Nuclear matrix protein SNEV) Length = 504 Score = 69.3 bits (168), Expect = 8e-12 Identities = 41/181 (22%), Positives = 75/181 (41%), Gaps = 44/181 (24%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 ++TGG D+ V ++ + +L G T V S+ F S+ ++ + + TI+IW + Sbjct: 237 ILTGGADKNVVVFDKSTEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIRIWSVPNT 296 Query: 369 KVVRTFTGHRSNCASLDSHPFGDF------------------------------------ 440 V+ H S L H GD+ Sbjct: 297 SCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCA 356 Query: 441 --------FASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 F +G+ D+ +KIWD++++ + + GH+G I + F+ +G ++ + DSSV Sbjct: 357 QFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSV 416 Query: 597 K 599 K Sbjct: 417 K 417 Score = 61.2 bits (147), Expect = 2e-09 Identities = 44/160 (27%), Positives = 68/160 (42%), Gaps = 6/160 (3%) Frame = +3 Query: 135 AHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLS-----FD 299 AH S VT T L++ +DQ WA L+ +T S F Sbjct: 304 AHESAVTGLSL-HATGDYLLSSSDDQ---YWAFSDIQTGRVLTKVTDETSGCSLTCAQFH 359 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 ++ G G IKIWD++E V F GH S+ G + A+ + D+++K+W Sbjct: 360 PDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLW 419 Query: 480 DMRKKRCIHTYQ-GHTGRIDVLRFTPDGRWIVSGGADSSV 596 D+RK + T Q + + L F G ++ GG D + Sbjct: 420 DLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTDVQI 459
>APAF_HUMAN (O14727) Apoptotic protease-activating factor 1 (Apaf-1)| Length = 1248 Score = 69.3 bits (168), Expect = 8e-12 Identities = 41/156 (26%), Positives = 73/156 (46%), Gaps = 2/156 (1%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMI 317 H V A F + R + + G D+ + ++ +L + V +F + + I Sbjct: 614 HTDAVYHACFSEDGQR-IASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFI 672 Query: 318 GAGAASGTIKIWDIEEAKVVRTFTGHRS--NCASLDSHPFGDFFASGSSDTNMKIWDMRK 491 + +KIW+ ++V T+ H NC + A+GSSD +K+WD+ + Sbjct: 673 ATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQ 732 Query: 492 KRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 K C +T GHT ++ RF+PD + + S AD ++K Sbjct: 733 KECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLK 768 Score = 52.8 bits (125), Expect = 8e-07 Identities = 33/124 (26%), Positives = 55/124 (44%), Gaps = 2/124 (1%) Frame = +3 Query: 117 KLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSF 296 KL E AH +V C F R + T D+KV +W V + + V F Sbjct: 649 KLLEIKAHEDEVLCCAFST-DDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHF 707 Query: 297 DSSE--VMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNM 470 +S +++ G++ +K+WD+ + + T GH ++ P AS S+D + Sbjct: 708 TNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTL 767 Query: 471 KIWD 482 K+WD Sbjct: 768 KLWD 771 Score = 50.4 bits (119), Expect = 4e-06 Identities = 31/139 (22%), Positives = 60/139 (43%) Frame = +3 Query: 183 RTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIE 362 +TLI+ +D ++ +W + L G V+ + ++ + + GT+K+W+I Sbjct: 1016 KTLISSSDDAEIQVWNWQLDKCIF-LRGHQETVKDFRLLKNSRLL-SWSFDGTVKVWNII 1073 Query: 363 EAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVL 542 + F H+ S D F+S S+D KIW +H +GH G + Sbjct: 1074 TGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCS 1133 Query: 543 RFTPDGRWIVSGGADSSVK 599 F+ D + +G + ++ Sbjct: 1134 AFSVDSTLLATGDDNGEIR 1152 Score = 42.0 bits (97), Expect = 0.001 Identities = 21/78 (26%), Positives = 37/78 (47%), Gaps = 1/78 (1%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLI-TGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVM 314 H+ V C F + L+ TG D + LW + + ++ G T+ V F + + Sbjct: 698 HSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKL 757 Query: 315 IGAGAASGTIKIWDIEEA 368 + + +A GT+K+WD A Sbjct: 758 LASCSADGTLKLWDATSA 775 Score = 37.4 bits (85), Expect = 0.033 Identities = 26/97 (26%), Positives = 45/97 (46%), Gaps = 12/97 (12%) Frame = +3 Query: 327 AASGTIKIWDIEEAKVVRTFTGH----RSNCASLDSHPFGDFFASGSSDTNMKIWDMRKK 494 +A T KIW + + GH R + S+DS A+G + ++IW++ Sbjct: 1104 SADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDS----TLLATGDDNGEIRIWNVSNG 1159 Query: 495 RCIH-----TYQG---HTGRIDVLRFTPDGRWIVSGG 581 +H + +G H G + L F+PDG+ ++S G Sbjct: 1160 ELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAG 1196 Score = 31.2 bits (69), Expect = 2.4 Identities = 15/77 (19%), Positives = 32/77 (41%) Frame = +3 Query: 261 SGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDF 440 +G S ++ F + + +++W+ + V GH S + P G Sbjct: 837 TGHHSTIQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSS 896 Query: 441 FASGSSDTNMKIWDMRK 491 F + S D +++W+ +K Sbjct: 897 FLTSSDDQTIRLWETKK 913 Score = 29.6 bits (65), Expect = 6.9 Identities = 30/112 (26%), Positives = 47/112 (41%), Gaps = 9/112 (8%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPT-----AVLSLSGLTSP-- 278 L E H V C+ F S L TG ++ ++ +W V A LS G + Sbjct: 1120 LHELRGHNGCVRCSAFSV-DSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGG 1178 Query: 279 -VESLSFD-SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHP 428 V L F +++I AG G IK W++ + +TF + +N + P Sbjct: 1179 WVTDLCFSPDGKMLISAG---GYIKWWNVVTGESSQTFYTNGTNLKKIHVSP 1227
>PRP19_CHICK (Q5ZMA2) Pre-mRNA-splicing factor 19 (PRP19/PSO4 homolog)| Length = 505 Score = 68.9 bits (167), Expect = 1e-11 Identities = 40/181 (22%), Positives = 76/181 (41%), Gaps = 44/181 (24%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 ++TGG D+ V ++ + +L G + V S+ F S+ ++ + + TI+IW + A Sbjct: 238 ILTGGADKNVIVFDKSSEQILATLKGHSKKVTSVVFHPSQDLVFSASPDATIRIWSVPNA 297 Query: 369 KVVRTFTGHRSNCASLDSHPFGDF------------------------------------ 440 V+ H + L H GD+ Sbjct: 298 SCVQVVRAHEGSVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDESSGCALTCA 357 Query: 441 --------FASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 F +G+ D+ +KIWD++++ + + GH+G I + F+ +G ++ + DSSV Sbjct: 358 QFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSV 417 Query: 597 K 599 K Sbjct: 418 K 418 Score = 58.5 bits (140), Expect = 1e-08 Identities = 30/102 (29%), Positives = 49/102 (48%), Gaps = 1/102 (0%) Frame = +3 Query: 294 FDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMK 473 F ++ G G IKIWD++E V F GH S+ G + A+ + D+++K Sbjct: 359 FHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVK 418 Query: 474 IWDMRKKRCIHTYQ-GHTGRIDVLRFTPDGRWIVSGGADSSV 596 +WD+RK + T Q + + L F G ++ GG D + Sbjct: 419 LWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTDVQI 460
>GBLP_YEAST (P38011) Guanine nucleotide-binding protein beta subunit-like| protein (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 318 Score = 68.9 bits (167), Expect = 1e-11 Identities = 46/170 (27%), Positives = 78/170 (45%), Gaps = 7/170 (4%) Frame = +3 Query: 96 MATKRAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTS 275 +AT Y Q FV H SDV K+ S +I+G D+ + +W + K + +L G Sbjct: 93 VATGETY--QRFVGHKSDVMSVDIDKKASM-IISGSRDKTIKVWTI-KGQCLATLLGHND 148 Query: 276 PVESLSF-------DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFG 434 V + D S +I AG +K W++ + ++ F GH SN +L + P G Sbjct: 149 WVSQVRVVPNEKADDDSVTIISAGNDK-MVKAWNLNQFQIEADFIGHNSNINTLTASPDG 207 Query: 435 DFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGA 584 AS D + +W++ K+ ++T + L F+P+ W+ + A Sbjct: 208 TLIASAGKDGEIMLWNLAAKKAMYTLSAQ-DEVFSLAFSPNRYWLAAATA 256 Score = 58.5 bits (140), Expect = 1e-08 Identities = 37/139 (26%), Positives = 62/139 (44%), Gaps = 6/139 (4%) Frame = +3 Query: 201 GEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVR 380 G+DQK + V S G + V+ + + + + T+++WD+ + + Sbjct: 48 GDDQKFGV-------PVRSFKGHSHIVQDCTLTADGAYALSASWDKTLRLWDVATGETYQ 100 Query: 381 TFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTP-- 554 F GH+S+ S+D SGS D +K+W + K +C+ T GH + +R P Sbjct: 101 RFVGHKSDVMSVDIDKKASMIISGSRDKTIKVWTI-KGQCLATLLGHNDWVSQVRVVPNE 159 Query: 555 ----DGRWIVSGGADSSVK 599 D I+S G D VK Sbjct: 160 KADDDSVTIISAGNDKMVK 178 Score = 53.5 bits (127), Expect = 4e-07 Identities = 37/136 (27%), Positives = 58/136 (42%), Gaps = 6/136 (4%) Frame = +3 Query: 207 DQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTF 386 D+ + LW V G S V S+ D MI +G+ TIK+W I+ + + T Sbjct: 85 DKTLRLWDVATGETYQRFVGHKSDVMSVDIDKKASMIISGSRDKTIKVWTIK-GQCLATL 143 Query: 387 TGHR---SNCASLDSHPFGD---FFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 GH S + + D S +D +K W++ + + + GH I+ L Sbjct: 144 LGHNDWVSQVRVVPNEKADDDSVTIISAGNDKMVKAWNLNQFQIEADFIGHNSNINTLTA 203 Query: 549 TPDGRWIVSGGADSSV 596 +PDG I S G D + Sbjct: 204 SPDGTLIASAGKDGEI 219
>TRCB_XENLA (Q91854) Beta-TrCP (Beta-transducin repeat-containing protein)| Length = 518 Score = 68.9 bits (167), Expect = 1e-11 Identities = 44/163 (26%), Positives = 74/163 (45%), Gaps = 3/163 (1%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLS---LSGLTSPVESL 290 L + H V +F + ++T +D+ + +W + T + L G + V + Sbjct: 305 LNTLIHHCEAVLHLRFN---NGMMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVV 361 Query: 291 SFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNM 470 FD ++ +G TIK+W+ + VRT GH+ A L SGSSD + Sbjct: 362 DFDDKYIVSASG--DRTIKVWNTSTCEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTI 417 Query: 471 KIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 ++WD+ C+ +GH + +RF D + IVSG D +K Sbjct: 418 RLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGAYDGKIK 458 Score = 44.3 bits (103), Expect = 3e-04 Identities = 31/124 (25%), Positives = 49/124 (39%), Gaps = 9/124 (7%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMI 317 H + C ++ R +++G D + LW + + L G V + FD+ ++ Sbjct: 394 HKRGIACLQY---RDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIV- 449 Query: 318 GAGAASGTIKIWDIEEA---------KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNM 470 +GA G IK+WD+ A +RT H L F S S D + Sbjct: 450 -SGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQ--IVSSSHDDTI 506 Query: 471 KIWD 482 IWD Sbjct: 507 LIWD 510 Score = 42.7 bits (99), Expect = 8e-04 Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 2/92 (2%) Frame = +3 Query: 279 VESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSN--CASLDSHPFGDFFASG 452 V L +D +++ +G TIKIWD + R GH + C D +G Sbjct: 235 VYCLQYDDQKIV--SGLRDNTIKIWDKNTLECKRVLMGHTGSVLCLQYDER----VIITG 288 Query: 453 SSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 SSD+ +++WD+ ++T H + LRF Sbjct: 289 SSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRF 320 Score = 41.6 bits (96), Expect = 0.002 Identities = 20/51 (39%), Positives = 29/51 (56%) Frame = +3 Query: 447 SGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 SG D +KIWD C GHTG + L++ D R I++G +DS+V+ Sbjct: 247 SGLRDNTIKIWDKNTLECKRVLMGHTGSVLCLQY--DERVIITGSSDSTVR 295
>PRL2_ARATH (Q39190) PP1/PP2A phosphatases pleiotropic regulator PRL2| Length = 479 Score = 68.6 bits (166), Expect = 1e-11 Identities = 37/135 (27%), Positives = 63/135 (46%) Frame = +3 Query: 195 TGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKV 374 TG D+ + +W V L+L+G V L+ + + + +K WD+E+ KV Sbjct: 187 TGSADRTIKIWDVATGVLKLTLTGHIGQVRGLAVSNRHTYMFSAGDDKQVKCWDLEQNKV 246 Query: 375 VRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTP 554 +R++ GH L HP D +G D+ ++WD+R K I + VL P Sbjct: 247 IRSYHGHLHGVYCLALHPTLDVVLTGGRDSVCRVWDIRTKMQIFVLPHDSDVFSVLA-RP 305 Query: 555 DGRWIVSGGADSSVK 599 +++G DS++K Sbjct: 306 TDPQVITGSHDSTIK 320 Score = 62.8 bits (151), Expect = 7e-10 Identities = 35/111 (31%), Positives = 50/111 (45%) Frame = +3 Query: 258 LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGD 437 L G V S++FD S G+A TIKIWD+ + T TGH L Sbjct: 166 LQGHLGWVRSVAFDPSNEWFCTGSADRTIKIWDVATGVLKLTLTGHIGQVRGLAVSNRHT 225 Query: 438 FFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADS 590 + S D +K WD+ + + I +Y GH + L P +++GG DS Sbjct: 226 YMFSAGDDKQVKCWDLEQNKVIRSYHGHLHGVYCLALHPTLDVVLTGGRDS 276 Score = 48.9 bits (115), Expect = 1e-05 Identities = 33/129 (25%), Positives = 56/129 (43%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 ++ + H V C T ++TGG D +W + + L S V S+ Sbjct: 247 IRSYHGHLHGVYCLALHP-TLDVVLTGGRDSVCRVWDIRTKMQIFVLPH-DSDVFSVLAR 304 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 ++ + G+ TIK WD+ K + T T H+ ++ HP + F S S+D N+K + Sbjct: 305 PTDPQVITGSHDSTIKFWDLRYGKSMATITNHKKTVRAMALHPKENDFVSASAD-NIKKF 363 Query: 480 DMRKKRCIH 506 + K H Sbjct: 364 SLPKGEFCH 372 Score = 42.4 bits (98), Expect = 0.001 Identities = 24/77 (31%), Positives = 36/77 (46%) Frame = +3 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 K R GH S+ P ++F +GS+D +KIWD+ T GH G++ L Sbjct: 161 KNYRVLQGHLGWVRSVAFDPSNEWFCTGSADRTIKIWDVATGVLKLTLTGHIGQVRGLAV 220 Query: 549 TPDGRWIVSGGADSSVK 599 + ++ S G D VK Sbjct: 221 SNRHTYMFSAGDDKQVK 237
>TLE4_RAT (Q07141) Transducin-like enhancer protein 4 (ESP2 protein)| Length = 741 Score = 68.6 bits (166), Expect = 1e-11 Identities = 38/141 (26%), Positives = 67/141 (47%), Gaps = 2/141 (1%) Frame = +3 Query: 183 RTLITGGEDQKVNLWAVGKPTAVLS--LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWD 356 RTLI GGE +++W + PT + L+ +L+ + + + G I +WD Sbjct: 514 RTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWD 573 Query: 357 IEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRID 536 + +VR F GH + +D G +G D ++ WD+R+ R + + T +I Sbjct: 574 LHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHD-FTSQIF 632 Query: 537 VLRFTPDGRWIVSGGADSSVK 599 L + P G W+ G +S+V+ Sbjct: 633 SLGYCPTGEWLAVGMENSNVE 653 Score = 54.7 bits (130), Expect = 2e-07 Identities = 43/166 (25%), Positives = 68/166 (40%), Gaps = 15/166 (9%) Frame = +3 Query: 147 DVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLS----------- 293 +V CA +R + TGG+ V +W + P G SPV L Sbjct: 456 EVVCAVTISNPTRHVYTGGKGC-VKVWDITDP-------GNKSPVSQLDCLNRDNYIRSC 507 Query: 294 --FDSSEVMIGAGAASGTIKIWDIEEA--KVVRTFTGHRSNCASLDSHPFGDFFASGSSD 461 +I G AS T+ IWD+ ++ T C +L P S SD Sbjct: 508 RLLPDGRTLIVGGEAS-TLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSD 566 Query: 462 TNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 N+ +WD+ + + +QGHT + + DG + +GG D++V+ Sbjct: 567 GNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVR 612
>TBLX_MOUSE (Q9QXE7) F-box-like/WD-repeat protein TBL1X (Transducin beta-like| 1X protein) Length = 527 Score = 68.6 bits (166), Expect = 1e-11 Identities = 40/167 (23%), Positives = 77/167 (46%), Gaps = 9/167 (5%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 Q+F H++ + T T + D +++ +G V + G T+ V ++ +D Sbjct: 315 QQFPFHSAPALDVDWQNNT--TFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDP 372 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGD---------FFASGS 455 S +++ + + T+KIW +++ V H ++ P G AS S Sbjct: 373 SGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSNIMLASAS 432 Query: 456 SDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 D+ +++WD+ + CIHT H + + F+PDG+++ SG D V Sbjct: 433 FDSTVRLWDVERGVCIHTLTKHQEPVYSVAFSPDGKYLASGSFDKCV 479 Score = 66.2 bits (160), Expect = 7e-11 Identities = 38/168 (22%), Positives = 80/168 (47%), Gaps = 9/168 (5%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 ++ F H ++V K+ + L + +D + +W++ + V L + + ++ + Sbjct: 355 VKTFQGHTNEVNAIKWDP-SGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWS 413 Query: 300 ---------SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASG 452 +S +M+ + + T+++WD+E + T T H+ S+ P G + ASG Sbjct: 414 PTGPATSNPNSNIMLASASFDSTVRLWDVERGVCIHTLTKHQEPVYSVAFSPDGKYLASG 473 Query: 453 SSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 S D + IW+ + +H+Y+G TG I + + G + + +D SV Sbjct: 474 SFDKCVHIWNTQSGSLVHSYRG-TGGIFEVCWNARGDKVGASASDGSV 520 Score = 45.8 bits (107), Expect = 9e-05 Identities = 33/137 (24%), Positives = 58/137 (42%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L TG D +W A +L P+ +L ++ I + T IWD Sbjct: 253 LATGSYDGFARIWTEDGNLAS-TLGQHKGPIFALKWNKKGNYILSAGVDKTTIIWDAHTG 311 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 + + F H + +D FAS S+D + + + R + T+QGHT ++ +++ Sbjct: 312 EAKQQFPFHSAPALDVDWQN-NTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKW 370 Query: 549 TPDGRWIVSGGADSSVK 599 P G + S D ++K Sbjct: 371 DPSGMLLASCSDDMTLK 387 Score = 38.9 bits (89), Expect = 0.011 Identities = 34/132 (25%), Positives = 55/132 (41%), Gaps = 14/132 (10%) Frame = +3 Query: 240 PTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAK-------VVRTFT--- 389 P+ L G S V +++ ++ +G+ T +IW++ E V+R Sbjct: 172 PSKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREG 231 Query: 390 GH----RSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPD 557 GH + SLD + G A+GS D +IW T H G I L++ Sbjct: 232 GHDVPSNKDVTSLDWNSDGTLLATGSYDGFARIW-TEDGNLASTLGQHKGPIFALKWNKK 290 Query: 558 GRWIVSGGADSS 593 G +I+S G D + Sbjct: 291 GNYILSAGVDKT 302
>TLE4_MOUSE (Q62441) Transducin-like enhancer protein 4 (Groucho-related| protein 4) (Grg-4) Length = 766 Score = 68.6 bits (166), Expect = 1e-11 Identities = 38/141 (26%), Positives = 67/141 (47%), Gaps = 2/141 (1%) Frame = +3 Query: 183 RTLITGGEDQKVNLWAVGKPTAVLS--LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWD 356 RTLI GGE +++W + PT + L+ +L+ + + + G I +WD Sbjct: 539 RTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWD 598 Query: 357 IEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRID 536 + +VR F GH + +D G +G D ++ WD+R+ R + + T +I Sbjct: 599 LHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHD-FTSQIF 657 Query: 537 VLRFTPDGRWIVSGGADSSVK 599 L + P G W+ G +S+V+ Sbjct: 658 SLGYCPTGEWLAVGMENSNVE 678 Score = 55.5 bits (132), Expect = 1e-07 Identities = 43/166 (25%), Positives = 68/166 (40%), Gaps = 15/166 (9%) Frame = +3 Query: 147 DVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLS----------- 293 +V CA +R + TGG+ V +W + P G SPV L Sbjct: 481 EVVCAVTISNPTRHVYTGGKGC-VKVWDISHP-------GNKSPVSQLDCLNRDNYIRSC 532 Query: 294 --FDSSEVMIGAGAASGTIKIWDIEEA--KVVRTFTGHRSNCASLDSHPFGDFFASGSSD 461 +I G AS T+ IWD+ ++ T C +L P S SD Sbjct: 533 RLLPDGRTLIVGGEAS-TLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSD 591 Query: 462 TNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 N+ +WD+ + + +QGHT + + DG + +GG D++V+ Sbjct: 592 GNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVR 637
>TLE4_HUMAN (Q04727) Transducin-like enhancer protein 4| Length = 766 Score = 68.6 bits (166), Expect = 1e-11 Identities = 38/141 (26%), Positives = 67/141 (47%), Gaps = 2/141 (1%) Frame = +3 Query: 183 RTLITGGEDQKVNLWAVGKPTAVLS--LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWD 356 RTLI GGE +++W + PT + L+ +L+ + + + G I +WD Sbjct: 539 RTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWD 598 Query: 357 IEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRID 536 + +VR F GH + +D G +G D ++ WD+R+ R + + T +I Sbjct: 599 LHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHD-FTSQIF 657 Query: 537 VLRFTPDGRWIVSGGADSSVK 599 L + P G W+ G +S+V+ Sbjct: 658 SLGYCPTGEWLAVGMENSNVE 678 Score = 55.5 bits (132), Expect = 1e-07 Identities = 43/166 (25%), Positives = 68/166 (40%), Gaps = 15/166 (9%) Frame = +3 Query: 147 DVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLS----------- 293 +V CA +R + TGG+ V +W + P G SPV L Sbjct: 481 EVVCAVTISNPTRHVYTGGKGC-VKVWDISHP-------GNKSPVSQLDCLNRDNYIRSC 532 Query: 294 --FDSSEVMIGAGAASGTIKIWDIEEA--KVVRTFTGHRSNCASLDSHPFGDFFASGSSD 461 +I G AS T+ IWD+ ++ T C +L P S SD Sbjct: 533 RLLPDGRTLIVGGEAS-TLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSD 591 Query: 462 TNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 N+ +WD+ + + +QGHT + + DG + +GG D++V+ Sbjct: 592 GNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVR 637
>YH92_CAEEL (Q23256) Hypothetical WD-repeat protein ZC302.2| Length = 501 Score = 68.6 bits (166), Expect = 1e-11 Identities = 36/122 (29%), Positives = 57/122 (46%) Frame = +3 Query: 234 GKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCAS 413 G+ + V ++SG T V + F +G G+A IK+W+ + ++T H+ Sbjct: 201 GEFSLVKTISGHTKSVSVIKFSYCGKYLGTGSADKQIKVWNTVDMTYLQTLASHQLGIND 260 Query: 414 LDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSS 593 F AS S DT +KI+D+ C+ T +GHT + F P I S G D + Sbjct: 261 FSWSSNSQFIASASDDTTVKIFDVISGACLRTMRGHTNYVFCCSFNPQSSLIASAGFDET 320 Query: 594 VK 599 V+ Sbjct: 321 VR 322 Score = 64.3 bits (155), Expect = 3e-10 Identities = 34/154 (22%), Positives = 66/154 (42%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMI 317 H V+ KF + L TG D+++ +W T + +L+ + S+ S+ I Sbjct: 212 HTKSVSVIKFSY-CGKYLGTGSADKQIKVWNTVDMTYLQTLASHQLGINDFSWSSNSQFI 270 Query: 318 GAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKR 497 + + T+KI+D+ +RT GH + +P AS D +++WD + Sbjct: 271 ASASDDTTVKIFDVISGACLRTMRGHTNYVFCCSFNPQSSLIASAGFDETVRVWDFKTGL 330 Query: 498 CIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 C+ H+ I + + DG + + D ++ Sbjct: 331 CVKCIPAHSDPITSISYNHDGNTMATSSYDGCIR 364 Score = 58.5 bits (140), Expect = 1e-08 Identities = 32/141 (22%), Positives = 67/141 (47%), Gaps = 1/141 (0%) Frame = +3 Query: 180 SRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDI 359 S+ + + +D V ++ V + ++ G T+ V SF+ +I + T+++WD Sbjct: 267 SQFIASASDDTTVKIFDVISGACLRTMRGHTNYVFCCSFNPQSSLIASAGFDETVRVWDF 326 Query: 360 EEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTY-QGHTGRID 536 + V+ H S+ + G+ A+ S D +++WD C+ T + Sbjct: 327 KTGLCVKCIPAHSDPITSISYNHDGNTMATSSYDGCIRVWDAASGSCLKTLVDTDHAPVT 386 Query: 537 VLRFTPDGRWIVSGGADSSVK 599 + F+P+G++++S DSS+K Sbjct: 387 FVCFSPNGKYLLSAQLDSSLK 407 Score = 57.8 bits (138), Expect = 2e-08 Identities = 35/155 (22%), Positives = 70/155 (45%), Gaps = 4/155 (2%) Frame = +3 Query: 135 AHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLT-SPVESLSFDSSEV 311 AH+ +T + T+ T D + +W + + +L +PV + F + Sbjct: 337 AHSDPITSISYN-HDGNTMATSSYDGCIRVWDAASGSCLKTLVDTDHAPVTFVCFSPNGK 395 Query: 312 MIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSH---PFGDFFASGSSDTNMKIWD 482 + + ++K+WD ++AK ++ + GH++ L ++ P G SGS D + +W Sbjct: 396 YLLSAQLDSSLKLWDPKKAKPLKYYNGHKNKKYCLFANMSVPLGKHIISGSEDGRILVWS 455 Query: 483 MRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGAD 587 ++ K+ + +GHT + P I SGG + Sbjct: 456 IQTKQIVQILEGHTTPVLATDSHPTLNIIASGGLE 490 Score = 43.1 bits (100), Expect = 6e-04 Identities = 27/121 (22%), Positives = 56/121 (46%) Frame = +3 Query: 237 KPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASL 416 KPT+ + ++ PV + ++SG K + E +V+T +GH + + + Sbjct: 171 KPTSTIQVAPPRDPVAPTT-----------SSSGITKKPENGEFSLVKTISGHTKSVSVI 219 Query: 417 DSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 G + +GS+D +K+W+ + T H I+ ++ + ++I S D++V Sbjct: 220 KFSYCGKYLGTGSADKQIKVWNTVDMTYLQTLASHQLGINDFSWSSNSQFIASASDDTTV 279 Query: 597 K 599 K Sbjct: 280 K 280 Score = 41.2 bits (95), Expect = 0.002 Identities = 28/103 (27%), Positives = 48/103 (46%), Gaps = 6/103 (5%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIG----AGAASGTIKIWD 356 L++ D + LW K + +G + L F + V +G +G+ G I +W Sbjct: 397 LLSAQLDSSLKLWDPKKAKPLKYYNGHKNKKYCL-FANMSVPLGKHIISGSEDGRILVWS 455 Query: 357 IEEAKVVRTFTGHRSNCASLDSHPFGDFFASG--SSDTNMKIW 479 I+ ++V+ GH + + DSHP + ASG D ++IW Sbjct: 456 IQTKQIVQILEGHTTPVLATDSHPTLNIIASGGLEPDNVIRIW 498
>Y143_SYNY3 (P74442) Hypothetical WD-repeat protein slr0143| Length = 1191 Score = 68.2 bits (165), Expect = 2e-11 Identities = 35/137 (25%), Positives = 67/137 (48%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 + + D V+LW + + +G T + + F + + T+KIWD++ Sbjct: 575 IASASRDGTVHLWTP-QGEFLREFTGHTGSIYRVDFSPNGKIFATAGQDQTVKIWDLD-G 632 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 +++T GH+ + S+ P G+ AS S D +++W R + + GHT +D +F Sbjct: 633 NLLQTLKGHQDSVYSVSFSPDGEILASTSRDRTVRLWHWRSGKTLAVLGGHTKSVDDAQF 692 Query: 549 TPDGRWIVSGGADSSVK 599 +PDG+ +VS D ++ Sbjct: 693 SPDGQTLVSVCRDGQIR 709 Score = 65.5 bits (158), Expect = 1e-10 Identities = 34/114 (29%), Positives = 59/114 (51%) Frame = +3 Query: 258 LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGD 437 L+G V S++ S + +I + + GT+ +W + + +R FTGH + +D P G Sbjct: 556 LTGHRDGVTSVAISSHKNLIASASRDGTVHLW-TPQGEFLREFTGHTGSIYRVDFSPNGK 614 Query: 438 FFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 FA+ D +KIWD+ + T +GH + + F+PDG + S D +V+ Sbjct: 615 IFATAGQDQTVKIWDL-DGNLLQTLKGHQDSVYSVSFSPDGEILASTSRDRTVR 667 Score = 53.1 bits (126), Expect = 6e-07 Identities = 26/108 (24%), Positives = 50/108 (46%) Frame = +3 Query: 276 PVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGS 455 P+ S+S + + AG G + +W+ + ++R+ H L P G + S Sbjct: 999 PIRSVSLHPTLPQLAAGDEQGNLTLWNFD-GTLIRSIVAHGDRLNQLQYSPNGKYLLSAG 1057 Query: 456 SDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 + KIW + + + +HT + ID + +PD +WI + +D V+ Sbjct: 1058 REGTAKIWSV-EGQLLHTLKSDPLPIDQIAISPDSQWIATAASDGMVR 1104 Score = 53.1 bits (126), Expect = 6e-07 Identities = 38/159 (23%), Positives = 65/159 (40%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 LQ H V F L + D+ V LW + L G T V+ F Sbjct: 635 LQTLKGHQDSVYSVSFSP-DGEILASTSRDRTVRLWHWRSGKTLAVLGGHTKSVDDAQFS 693 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 + + G I++WD++ ++R F ++ HP G+ A + D +++W Sbjct: 694 PDGQTLVSVCRDGQIRLWDLD-GNLIRQFGLPEVAFFGVNWHPNGNLLAVAADDGTVRLW 752 Query: 480 DMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 + + T GH + + FTPDG+ + S ++ SV Sbjct: 753 TPQGE-IKATLSGHDEFVTRVVFTPDGKQLFSSSSNGSV 790 Score = 50.1 bits (118), Expect = 5e-06 Identities = 28/122 (22%), Positives = 50/122 (40%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 L+EF H + F + T G+DQ V +W + + +L G V S+SF Sbjct: 594 LREFTGHTGSIYRVDFSPN-GKIFATAGQDQTVKIWDLDG-NLLQTLKGHQDSVYSVSFS 651 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 ++ + + T+++W K + GH + P G S D +++W Sbjct: 652 PDGEILASTSRDRTVRLWHWRSGKTLAVLGGHTKSVDDAQFSPDGQTLVSVCRDGQIRLW 711 Query: 480 DM 485 D+ Sbjct: 712 DL 713 Score = 35.8 bits (81), Expect = 0.097 Identities = 20/126 (15%), Positives = 57/126 (45%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 ++ VAH + ++ + L++ G + +W+V + + +L P++ ++ Sbjct: 1031 IRSIVAHGDRLNQLQYSPN-GKYLLSAGREGTAKIWSV-EGQLLHTLKSDPLPIDQIAIS 1088 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 I A+ G +++WD ++ + FT + LD + G + + + + +++ W Sbjct: 1089 PDSQWIATAASDGMVRLWD-QQGNLRGEFTSTSGSLLGLDFNRQGQWLLAVAQNGDLQSW 1147 Query: 480 DMRKKR 497 + ++ Sbjct: 1148 PVTPEK 1153
>FBW1B_HUMAN (Q9UKB1) F-box/WD-repeat protein 11 (F-box/WD-repeat protein 1B)| (F-box and WD-repeats protein beta-TrCP2) Length = 542 Score = 68.2 bits (165), Expect = 2e-11 Identities = 40/140 (28%), Positives = 66/140 (47%), Gaps = 3/140 (2%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLS---LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDI 359 ++T +D+ + +W + T + L G + V + FD ++ +G TIK+W Sbjct: 333 MVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASG--DRTIKVWST 390 Query: 360 EEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDV 539 + VRT GH+ A L SGSSD +++WD+ C+ +GH + Sbjct: 391 STCEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRC 448 Query: 540 LRFTPDGRWIVSGGADSSVK 599 +RF D + IVSG D +K Sbjct: 449 IRF--DNKRIVSGAYDGKIK 466 Score = 45.4 bits (106), Expect = 1e-04 Identities = 31/124 (25%), Positives = 50/124 (40%), Gaps = 9/124 (7%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMI 317 H + C ++ R +++G D + LW + + L G V + FD+ ++ Sbjct: 402 HKRGIACLQY---RDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIV- 457 Query: 318 GAGAASGTIKIWDIEEA---------KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNM 470 +GA G IK+WD++ A +RT H L F S S D + Sbjct: 458 -SGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQ--IISSSHDDTI 514 Query: 471 KIWD 482 IWD Sbjct: 515 LIWD 518 Score = 44.7 bits (104), Expect = 2e-04 Identities = 25/93 (26%), Positives = 45/93 (48%), Gaps = 2/93 (2%) Frame = +3 Query: 279 VESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSN--CASLDSHPFGDFFASG 452 V L +D +++ +G +IKIWD + ++ TGH + C D +G Sbjct: 243 VYCLQYDDEKII--SGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDER----VIVTG 296 Query: 453 SSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFT 551 SSD+ +++WD+ ++T H + LRF+ Sbjct: 297 SSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFS 329 Score = 43.5 bits (101), Expect = 5e-04 Identities = 21/51 (41%), Positives = 31/51 (60%) Frame = +3 Query: 447 SGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 SG D ++KIWD C+ GHTG + L++ D R IV+G +DS+V+ Sbjct: 255 SGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQY--DERVIVTGSSDSTVR 303
>COPB2_DROME (O62621) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| Length = 914 Score = 67.8 bits (164), Expect = 2e-11 Identities = 45/165 (27%), Positives = 75/165 (45%), Gaps = 4/165 (2%) Frame = +3 Query: 117 KLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSL-SGLTSPVESLS 293 K+ F AH+ + C T ++T +D + LW K A + G T V + Sbjct: 91 KVHSFEAHSDYLRCIAVHP-TQPLVLTSSDDMLIKLWNWEKMWACQRVFEGHTHYVMQIV 149 Query: 294 FDSSEVMIGAGAA-SGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGD--FFASGSSDT 464 F+ + A A+ T+K+W + T GH +D + GD + SG+ D Sbjct: 150 FNPKDNNTFASASLDRTVKVWQLGSNFANFTLEGHEKGVNCVDYYHGGDKPYLISGADDR 209 Query: 465 NMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 +KIWD + K C+ T +GH I + F P+ +++G D +V+ Sbjct: 210 LVKIWDYQNKTCVQTLEGHAQNISAVCFHPELPIVLTGSEDGTVR 254 Score = 54.3 bits (129), Expect = 3e-07 Identities = 31/119 (26%), Positives = 52/119 (43%), Gaps = 2/119 (1%) Frame = +3 Query: 129 FVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSF--DS 302 F H V F + + T + D+ V +W +G A +L G V + + Sbjct: 138 FEGHTHYVMQIVFNPKDNNTFASASLDRTVKVWQLGSNFANFTLEGHEKGVNCVDYYHGG 197 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 + + +GA +KIWD + V+T GH N +++ HP +GS D ++IW Sbjct: 198 DKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNISAVCFHPELPIVLTGSEDGTVRIW 256 Score = 43.9 bits (102), Expect = 4e-04 Identities = 28/110 (25%), Positives = 47/110 (42%), Gaps = 2/110 (1%) Frame = +3 Query: 276 PVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGS 455 PV S F + + I G+ I++++ + V +F H + HP + S Sbjct: 59 PVRSARFVARKNWILTGSDDMQIRVFNYNTLEKVHSFEAHSDYLRCIAVHPTQPLVLTSS 118 Query: 456 SDTNMKIWDMRKK-RCIHTYQGHTGRIDVLRFTP-DGRWIVSGGADSSVK 599 D +K+W+ K C ++GHT + + F P D S D +VK Sbjct: 119 DDMLIKLWNWEKMWACQRVFEGHTHYVMQIVFNPKDNNTFASASLDRTVK 168
>TLE3_HUMAN (Q04726) Transducin-like enhancer protein 3 (ESG3)| Length = 772 Score = 67.8 bits (164), Expect = 2e-11 Identities = 38/141 (26%), Positives = 65/141 (46%), Gaps = 2/141 (1%) Frame = +3 Query: 183 RTLITGGEDQKVNLWAVGKPTAVLS--LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWD 356 RTLI GGE + +W + PT + L+ +L+ + + + G I +WD Sbjct: 545 RTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWD 604 Query: 357 IEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRID 536 + +VR F GH + +D G +G D ++ WD+R+ R + + T +I Sbjct: 605 LHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHD-FTSQIF 663 Query: 537 VLRFTPDGRWIVSGGADSSVK 599 L + P G W+ G S+V+ Sbjct: 664 SLGYCPTGEWLAVGMESSNVE 684 Score = 56.6 bits (135), Expect = 5e-08 Identities = 38/158 (24%), Positives = 70/158 (44%), Gaps = 7/158 (4%) Frame = +3 Query: 147 DVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVM---- 314 +V CA +R + TGG+ V +W + +P + +S L S +++ Sbjct: 487 EVVCAVTISNPTRHVYTGGKGC-VKIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPDGR 545 Query: 315 -IGAGAASGTIKIWDIEEA--KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDM 485 + G + T+ IWD+ ++ T C +L P S SD N+ +WD+ Sbjct: 546 TLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDL 605 Query: 486 RKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 + + +QGHT + + DG + +GG D++V+ Sbjct: 606 HNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVR 643
>GBB2_RAT (P54313) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 2 (Transducin beta chain 2) (G protein beta 2 subunit) Length = 339 Score = 67.8 bits (164), Expect = 2e-11 Identities = 40/139 (28%), Positives = 67/139 (48%), Gaps = 5/139 (3%) Frame = +3 Query: 198 GGEDQKVNLWAV----GKPTAVLSLSGLTSPVESLSF-DSSEVMIGAGAASGTIKIWDIE 362 GG D +++++ G L G T + F D ++++ +G T +WDIE Sbjct: 114 GGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDT--TCALWDIE 171 Query: 363 EAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVL 542 + F GH + SL P G F SG+ D ++K+WD+R C T+ GH I+ + Sbjct: 172 TGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAV 231 Query: 543 RFTPDGRWIVSGGADSSVK 599 F P+G +G D++ + Sbjct: 232 AFFPNGYAFTTGSDDATCR 250 Score = 64.7 bits (156), Expect = 2e-10 Identities = 39/157 (24%), Positives = 74/157 (47%), Gaps = 2/157 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 +E H ++C +F +IT D LW + + +G + V SLS Sbjct: 136 RELPGHTGYLSCCRF--LDDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAP 193 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 +GA +IK+WD+ ++ +TF GH S+ ++ P G F +GS D +++D Sbjct: 194 DGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFD 253 Query: 483 MR--KKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGAD 587 +R ++ ++++ I + F+ GR +++G D Sbjct: 254 LRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDD 290 Score = 42.4 bits (98), Expect = 0.001 Identities = 31/122 (25%), Positives = 50/122 (40%), Gaps = 2/122 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLS--GLTSPVESLSF 296 Q F+ H SD+ F TG +D L+ + +L S + + S++F Sbjct: 219 QTFIGHESDINAVAFFPN-GYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAF 277 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 S ++ AG IWD + GH + + L G A+GS D+ +KI Sbjct: 278 SRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKI 337 Query: 477 WD 482 W+ Sbjct: 338 WN 339 Score = 32.3 bits (72), Expect = 1.1 Identities = 16/71 (22%), Positives = 27/71 (38%) Frame = +3 Query: 378 RTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPD 557 RT GH + ++ S S D + IWD +H + + + P Sbjct: 48 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPS 107 Query: 558 GRWIVSGGADS 590 G ++ GG D+ Sbjct: 108 GNFVACGGLDN 118
>GBB2_MOUSE (P62880) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 2 (Transducin beta chain 2) (G protein beta 2 subunit) Length = 339 Score = 67.8 bits (164), Expect = 2e-11 Identities = 40/139 (28%), Positives = 67/139 (48%), Gaps = 5/139 (3%) Frame = +3 Query: 198 GGEDQKVNLWAV----GKPTAVLSLSGLTSPVESLSF-DSSEVMIGAGAASGTIKIWDIE 362 GG D +++++ G L G T + F D ++++ +G T +WDIE Sbjct: 114 GGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDT--TCALWDIE 171 Query: 363 EAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVL 542 + F GH + SL P G F SG+ D ++K+WD+R C T+ GH I+ + Sbjct: 172 TGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAV 231 Query: 543 RFTPDGRWIVSGGADSSVK 599 F P+G +G D++ + Sbjct: 232 AFFPNGYAFTTGSDDATCR 250 Score = 64.7 bits (156), Expect = 2e-10 Identities = 39/157 (24%), Positives = 74/157 (47%), Gaps = 2/157 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 +E H ++C +F +IT D LW + + +G + V SLS Sbjct: 136 RELPGHTGYLSCCRF--LDDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAP 193 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 +GA +IK+WD+ ++ +TF GH S+ ++ P G F +GS D +++D Sbjct: 194 DGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFD 253 Query: 483 MR--KKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGAD 587 +R ++ ++++ I + F+ GR +++G D Sbjct: 254 LRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDD 290 Score = 42.4 bits (98), Expect = 0.001 Identities = 31/122 (25%), Positives = 50/122 (40%), Gaps = 2/122 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLS--GLTSPVESLSF 296 Q F+ H SD+ F TG +D L+ + +L S + + S++F Sbjct: 219 QTFIGHESDINAVAFFPN-GYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAF 277 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 S ++ AG IWD + GH + + L G A+GS D+ +KI Sbjct: 278 SRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKI 337 Query: 477 WD 482 W+ Sbjct: 338 WN 339 Score = 32.3 bits (72), Expect = 1.1 Identities = 16/71 (22%), Positives = 27/71 (38%) Frame = +3 Query: 378 RTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPD 557 RT GH + ++ S S D + IWD +H + + + P Sbjct: 48 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPS 107 Query: 558 GRWIVSGGADS 590 G ++ GG D+ Sbjct: 108 GNFVACGGLDN 118
>GBB2_HUMAN (P62879) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 2 (Transducin beta chain 2) (G protein beta 2 subunit) Length = 339 Score = 67.8 bits (164), Expect = 2e-11 Identities = 40/139 (28%), Positives = 67/139 (48%), Gaps = 5/139 (3%) Frame = +3 Query: 198 GGEDQKVNLWAV----GKPTAVLSLSGLTSPVESLSF-DSSEVMIGAGAASGTIKIWDIE 362 GG D +++++ G L G T + F D ++++ +G T +WDIE Sbjct: 114 GGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDT--TCALWDIE 171 Query: 363 EAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVL 542 + F GH + SL P G F SG+ D ++K+WD+R C T+ GH I+ + Sbjct: 172 TGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAV 231 Query: 543 RFTPDGRWIVSGGADSSVK 599 F P+G +G D++ + Sbjct: 232 AFFPNGYAFTTGSDDATCR 250 Score = 64.7 bits (156), Expect = 2e-10 Identities = 39/157 (24%), Positives = 74/157 (47%), Gaps = 2/157 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 +E H ++C +F +IT D LW + + +G + V SLS Sbjct: 136 RELPGHTGYLSCCRF--LDDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAP 193 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 +GA +IK+WD+ ++ +TF GH S+ ++ P G F +GS D +++D Sbjct: 194 DGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFD 253 Query: 483 MR--KKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGAD 587 +R ++ ++++ I + F+ GR +++G D Sbjct: 254 LRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDD 290 Score = 42.4 bits (98), Expect = 0.001 Identities = 31/122 (25%), Positives = 50/122 (40%), Gaps = 2/122 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLS--GLTSPVESLSF 296 Q F+ H SD+ F TG +D L+ + +L S + + S++F Sbjct: 219 QTFIGHESDINAVAFFPN-GYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAF 277 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 S ++ AG IWD + GH + + L G A+GS D+ +KI Sbjct: 278 SRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKI 337 Query: 477 WD 482 W+ Sbjct: 338 WN 339 Score = 32.3 bits (72), Expect = 1.1 Identities = 16/71 (22%), Positives = 27/71 (38%) Frame = +3 Query: 378 RTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPD 557 RT GH + ++ S S D + IWD +H + + + P Sbjct: 48 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPS 107 Query: 558 GRWIVSGGADS 590 G ++ GG D+ Sbjct: 108 GNFVACGGLDN 118
>GBB2_BOVIN (P11017) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 2 (Transducin beta chain 2) (G protein beta 2 subunit) (Fragment) Length = 326 Score = 67.8 bits (164), Expect = 2e-11 Identities = 40/139 (28%), Positives = 67/139 (48%), Gaps = 5/139 (3%) Frame = +3 Query: 198 GGEDQKVNLWAV----GKPTAVLSLSGLTSPVESLSF-DSSEVMIGAGAASGTIKIWDIE 362 GG D +++++ G L G T + F D ++++ +G T +WDIE Sbjct: 101 GGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDT--TCALWDIE 158 Query: 363 EAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVL 542 + F GH + SL P G F SG+ D ++K+WD+R C T+ GH I+ + Sbjct: 159 TGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAV 218 Query: 543 RFTPDGRWIVSGGADSSVK 599 F P+G +G D++ + Sbjct: 219 AFFPNGYAFTTGSDDATCR 237 Score = 64.7 bits (156), Expect = 2e-10 Identities = 39/157 (24%), Positives = 74/157 (47%), Gaps = 2/157 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 +E H ++C +F +IT D LW + + +G + V SLS Sbjct: 123 RELPGHTGYLSCCRF--LDDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAP 180 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 +GA +IK+WD+ ++ +TF GH S+ ++ P G F +GS D +++D Sbjct: 181 DGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFD 240 Query: 483 MR--KKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGAD 587 +R ++ ++++ I + F+ GR +++G D Sbjct: 241 LRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDD 277 Score = 42.4 bits (98), Expect = 0.001 Identities = 31/122 (25%), Positives = 50/122 (40%), Gaps = 2/122 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLS--GLTSPVESLSF 296 Q F+ H SD+ F TG +D L+ + +L S + + S++F Sbjct: 206 QTFIGHESDINAVAFFPN-GYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAF 264 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 S ++ AG IWD + GH + + L G A+GS D+ +KI Sbjct: 265 SRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKI 324 Query: 477 WD 482 W+ Sbjct: 325 WN 326 Score = 32.3 bits (72), Expect = 1.1 Identities = 16/71 (22%), Positives = 27/71 (38%) Frame = +3 Query: 378 RTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPD 557 RT GH + ++ S S D + IWD +H + + + P Sbjct: 35 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPS 94 Query: 558 GRWIVSGGADS 590 G ++ GG D+ Sbjct: 95 GNFVACGGLDN 105
>GBB_LYMST (Q08706) Guanine nucleotide-binding protein beta subunit| Length = 341 Score = 67.8 bits (164), Expect = 2e-11 Identities = 39/139 (28%), Positives = 67/139 (48%), Gaps = 5/139 (3%) Frame = +3 Query: 198 GGEDQKVNLWAV----GKPTAVLSLSGLTSPVESLSF-DSSEVMIGAGAASGTIKIWDIE 362 GG D +++++ G L G T + F D + ++ +G S +WDIE Sbjct: 116 GGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFIDDNSIVTSSGDMS--CALWDIE 173 Query: 363 EAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVL 542 + +FTGH + SL + P F SG+ D + K+WD+R C T+ GH I+ + Sbjct: 174 TGQQTTSFTGHTGDVMSLSTSPDFRTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAI 233 Query: 543 RFTPDGRWIVSGGADSSVK 599 + P+G +G D++ + Sbjct: 234 TYFPNGHAFATGSDDATCR 252 Score = 67.4 bits (163), Expect = 3e-11 Identities = 48/203 (23%), Positives = 74/203 (36%), Gaps = 44/203 (21%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 +E H ++C +F S ++T D LW + S +G T V SLS Sbjct: 138 RELPGHTGYLSCCRFIDDNS--IVTSSGDMSCALWDIETGQQTTSFTGHTGDVMSLSTSP 195 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDT------ 464 +GA + K+WD+ + +TF+GH S+ ++ P G FA+GS D Sbjct: 196 DFRTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDATCRLFD 255 Query: 465 --------------------------------------NMKIWDMRKKRCIHTYQGHTGR 530 N +WD+ K+ GH R Sbjct: 256 IRADQEIGMYSHDNIICGITSVAFSKSGRLLLGRYDDFNCNVWDVLKQETHGVLAGHDNR 315 Query: 531 IDVLRFTPDGRWIVSGGADSSVK 599 + L T DG + +G DS +K Sbjct: 316 VSCLGVTEDGSAVATGSWDSFLK 338 Score = 37.7 bits (86), Expect = 0.026 Identities = 26/122 (21%), Positives = 49/122 (40%), Gaps = 2/122 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAV--GKPTAVLSLSGLTSPVESLSF 296 Q F H SD+ + TG +D L+ + + + S + + S++F Sbjct: 221 QTFSGHESDINAITYFPN-GHAFATGSDDATCRLFDIRADQEIGMYSHDNIICGITSVAF 279 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 S ++ +WD+ + + GH + + L G A+GS D+ +KI Sbjct: 280 SKSGRLLLGRYDDFNCNVWDVLKQETHGVLAGHDNRVSCLGVTEDGSAVATGSWDSFLKI 339 Query: 477 WD 482 W+ Sbjct: 340 WN 341 Score = 31.6 bits (70), Expect = 1.8 Identities = 26/117 (22%), Positives = 41/117 (35%), Gaps = 6/117 (5%) Frame = +3 Query: 258 LSGLTSPVESLSFDSSEVMIGAG------AASGTIKIWDIEEAKVVRTFTGHRSNCASLD 419 L L E L E AG A SG + I+ + RT GH + ++ Sbjct: 5 LEALRQETEQLKNQIREARKAAGDTTLAQACSGVEAVGRIQ-MRTRRTLRGHLAKIYAMH 63 Query: 420 SHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADS 590 S S D + +WD +H + + + P G ++ GG D+ Sbjct: 64 WASDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDN 120
>TLE3_RAT (Q9JIT3) Transducin-like enhancer protein 3 (rTLE3)| Length = 764 Score = 67.8 bits (164), Expect = 2e-11 Identities = 38/141 (26%), Positives = 65/141 (46%), Gaps = 2/141 (1%) Frame = +3 Query: 183 RTLITGGEDQKVNLWAVGKPTAVLS--LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWD 356 RTLI GGE + +W + PT + L+ +L+ + + + G I +WD Sbjct: 537 RTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWD 596 Query: 357 IEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRID 536 + +VR F GH + +D G +G D ++ WD+R+ R + + T +I Sbjct: 597 LHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHD-FTSQIF 655 Query: 537 VLRFTPDGRWIVSGGADSSVK 599 L + P G W+ G S+V+ Sbjct: 656 SLGYCPTGEWLAVGMESSNVE 676 Score = 56.6 bits (135), Expect = 5e-08 Identities = 38/158 (24%), Positives = 70/158 (44%), Gaps = 7/158 (4%) Frame = +3 Query: 147 DVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVM---- 314 +V CA +R + TGG+ V +W + +P + +S L S +++ Sbjct: 479 EVVCAVTISNPTRHVYTGGKGC-VKIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPDGR 537 Query: 315 -IGAGAASGTIKIWDIEEA--KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDM 485 + G + T+ IWD+ ++ T C +L P S SD N+ +WD+ Sbjct: 538 TLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDL 597 Query: 486 RKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 + + +QGHT + + DG + +GG D++V+ Sbjct: 598 HNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVR 635
>TLE3_MOUSE (Q08122) Transducin-like enhancer protein 3 (ESG) (Grg-3)| Length = 771 Score = 67.8 bits (164), Expect = 2e-11 Identities = 38/141 (26%), Positives = 65/141 (46%), Gaps = 2/141 (1%) Frame = +3 Query: 183 RTLITGGEDQKVNLWAVGKPTAVLS--LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWD 356 RTLI GGE + +W + PT + L+ +L+ + + + G I +WD Sbjct: 544 RTLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWD 603 Query: 357 IEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRID 536 + +VR F GH + +D G +G D ++ WD+R+ R + + T +I Sbjct: 604 LHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHD-FTSQIF 662 Query: 537 VLRFTPDGRWIVSGGADSSVK 599 L + P G W+ G S+V+ Sbjct: 663 SLGYCPTGEWLAVGMESSNVE 683 Score = 56.6 bits (135), Expect = 5e-08 Identities = 38/158 (24%), Positives = 70/158 (44%), Gaps = 7/158 (4%) Frame = +3 Query: 147 DVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVM---- 314 +V CA +R + TGG+ V +W + +P + +S L S +++ Sbjct: 486 EVVCAVTISNPTRHVYTGGKGC-VKIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPDGR 544 Query: 315 -IGAGAASGTIKIWDIEEA--KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDM 485 + G + T+ IWD+ ++ T C +L P S SD N+ +WD+ Sbjct: 545 TLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDL 604 Query: 486 RKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 + + +QGHT + + DG + +GG D++V+ Sbjct: 605 HNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVR 642
>WDR48_MOUSE (Q8BH57) WD-repeat protein 48| Length = 676 Score = 67.4 bits (163), Expect = 3e-11 Identities = 40/143 (27%), Positives = 67/143 (46%), Gaps = 9/143 (6%) Frame = +3 Query: 195 TGGEDQKVNLWAVGKPTAVL---------SLSGLTSPVESLSFDSSEVMIGAGAASGTIK 347 + G D+++ LW V TA+ SLSG + SL+ + +I +G+ ++ Sbjct: 134 SAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLR 193 Query: 348 IWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTG 527 +WD + GH N +L H G SGSSD +++W + ++RCI TY+ H Sbjct: 194 VWDPRTCAKLMKLKGHTDNVKALLLHRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDE 253 Query: 528 RIDVLRFTPDGRWIVSGGADSSV 596 + L+ + SGG D + Sbjct: 254 GVWALQVNDAFTHVYSGGRDRKI 276 Score = 58.5 bits (140), Expect = 1e-08 Identities = 32/148 (21%), Positives = 67/148 (45%), Gaps = 9/148 (6%) Frame = +3 Query: 183 RTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIE 362 +TLI+ D V +W K + +L V++L++ + ++ + I +WD+ Sbjct: 88 KTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVN 147 Query: 363 EAKVVR---------TFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQ 515 + + +G++ + SL + G SGS++ +++WD R + + Sbjct: 148 TLTALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLK 207 Query: 516 GHTGRIDVLRFTPDGRWIVSGGADSSVK 599 GHT + L DG +SG +D +++ Sbjct: 208 GHTDNVKALLLHRDGTQCLSGSSDGTIR 235 Score = 41.6 bits (96), Expect = 0.002 Identities = 25/109 (22%), Positives = 43/109 (39%), Gaps = 3/109 (2%) Frame = +3 Query: 279 VESLSFDSSEVMIGAGAASGTIKIWDIEEAK---VVRTFTGHRSNCASLDSHPFGDFFAS 449 V +L D + + I+IW + + K + + H + G S Sbjct: 33 VNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDVVLCCNGKTLIS 92 Query: 450 GSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 SSDT +K+W+ K C+ T + H + L + D + S G D + Sbjct: 93 ASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQI 141 Score = 40.4 bits (93), Expect = 0.004 Identities = 24/102 (23%), Positives = 45/102 (44%), Gaps = 1/102 (0%) Frame = +3 Query: 186 TLITGGEDQKV-NLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIE 362 T+I G +KV +W ++ L G T V++L +G++ GTI++W + Sbjct: 181 TIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLHRDGTQCLSGSSDGTIRLWSLG 240 Query: 363 EAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMR 488 + + + T+ H +L + SG D + D+R Sbjct: 241 QQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLR 282
>GBB_ARATH (P49177) Guanine nucleotide-binding protein beta subunit| (transducin) (AGB1) Length = 377 Score = 67.4 bits (163), Expect = 3e-11 Identities = 49/163 (30%), Positives = 76/163 (46%), Gaps = 11/163 (6%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAV--GKPTAVLS---LSGLTSPVESLSFDS 302 H V+C ++ LIT DQ LW V G T+V SG T+ V S+S Sbjct: 155 HRGYVSCCQYVPNEDAHLITSSGDQTCILWDVTTGLKTSVFGGEFQSGHTADVLSVSISG 214 Query: 303 SEV-MIGAGAASGTIKIWDIEEA-KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 S +G+ T ++WD A + VRTF GH + ++ P G F +GS D ++ Sbjct: 215 SNPNWFISGSCDSTARLWDTRAASRAVRTFHGHEGDVNTVKFFPDGYRFGTGSDDGTCRL 274 Query: 477 WDMRKKRCIHTYQ----GHTGRIDVLRFTPDGRWIVSGGADSS 593 +D+R + YQ G G + + F+ GR + +G A ++ Sbjct: 275 YDIRTGHQLQVYQPHGDGENGPVTSIAFSVSGRLLFAGYASNN 317 Score = 49.3 bits (116), Expect = 8e-06 Identities = 28/96 (29%), Positives = 49/96 (51%), Gaps = 9/96 (9%) Frame = +3 Query: 339 TIKIWDIEEAKVVRTF-----TGHRSNCASLD---SHPFGDFFASGSSDTNMKIWDMRK- 491 T +WD+ F +GH ++ S+ S+P ++F SGS D+ ++WD R Sbjct: 180 TCILWDVTTGLKTSVFGGEFQSGHTADVLSVSISGSNP--NWFISGSCDSTARLWDTRAA 237 Query: 492 KRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 R + T+ GH G ++ ++F PDG +G D + + Sbjct: 238 SRAVRTFHGHEGDVNTVKFFPDGYRFGTGSDDGTCR 273 Score = 42.0 bits (97), Expect = 0.001 Identities = 39/129 (30%), Positives = 55/129 (42%), Gaps = 9/129 (6%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAV--GKPTAVLSL--SGLTSPVES 287 ++ F H DV KF R TG +D L+ + G V G PV S Sbjct: 241 VRTFHGHEGDVNTVKFFPDGYR-FGTGSDDGTCRLYDIRTGHQLQVYQPHGDGENGPVTS 299 Query: 288 LSFDSSEVMIGAGAASG-TIKIWDIEEAKVVRTF----TGHRSNCASLDSHPFGDFFASG 452 ++F S ++ AG AS T +WD +VV HR+ + L G +G Sbjct: 300 IAFSVSGRLLFAGYASNNTCYVWDTLLGEVVLDLGLQQDSHRNRISCLGLSADGSALCTG 359 Query: 453 SSDTNMKIW 479 S D+N+KIW Sbjct: 360 SWDSNLKIW 368 Score = 37.4 bits (85), Expect = 0.033 Identities = 20/71 (28%), Positives = 31/71 (43%) Frame = +3 Query: 378 RTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPD 557 RT GH SLD P + S S D + +W+ + H + + F+P+ Sbjct: 59 RTLQGHTGKVYSLDWTPERNRIVSASQDGRLIVWNALTSQKTHAIKLPCAWVMTCAFSPN 118 Query: 558 GRWIVSGGADS 590 G+ + GG DS Sbjct: 119 GQSVACGGLDS 129 Score = 32.0 bits (71), Expect = 1.4 Identities = 14/30 (46%), Positives = 18/30 (60%) Frame = +3 Query: 498 CIHTYQGHTGRIDVLRFTPDGRWIVSGGAD 587 C T QGHTG++ L +TP+ IVS D Sbjct: 57 CCRTLQGHTGKVYSLDWTPERNRIVSASQD 86
>GBLP_SCHPO (Q10281) Guanine nucleotide-binding protein beta subunit-like| protein (Receptor of activated protein kinase C) Length = 314 Score = 67.4 bits (163), Expect = 3e-11 Identities = 41/142 (28%), Positives = 63/142 (44%), Gaps = 3/142 (2%) Frame = +3 Query: 180 SRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDI 359 S ++ D+ + LW + K G TS V S+S + +G+ TIKIW+I Sbjct: 75 SHYALSASWDKTIRLWDLEKGECTHQFVGHTSDVLSVSISPDNRQVVSGSRDKTIKIWNI 134 Query: 360 -EEAKVVRTFTGHRS--NCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGR 530 K T GH +C +P F S D +K+WD+ ++ GHTG Sbjct: 135 IGNCKYTITDGGHSDWVSCVRFSPNPDNLTFVSAGWDKAVKVWDLETFSLRTSHYGHTGY 194 Query: 531 IDVLRFTPDGRWIVSGGADSSV 596 + + +PDG SGG D ++ Sbjct: 195 VSAVTISPDGSLCASGGRDGTL 216 Score = 61.2 bits (147), Expect = 2e-09 Identities = 40/126 (31%), Positives = 66/126 (52%), Gaps = 11/126 (8%) Frame = +3 Query: 255 SLSGLTSPVESLSF--DSSEVMIGAGAASGTIKIW-----DIEEAKVVRTFTGHR---SN 404 +L G + V SLS ++ ++++ +G+ +I +W D+ R TGH S+ Sbjct: 10 TLEGHSGWVTSLSTAPENPDILL-SGSRDKSIILWNLVRDDVNYGVAQRRLTGHSHFVSD 68 Query: 405 CA-SLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGG 581 CA S DSH + S S D +++WD+ K C H + GHT + + +PD R +VSG Sbjct: 69 CALSFDSH----YALSASWDKTIRLWDLEKGECTHQFVGHTSDVLSVSISPDNRQVVSGS 124 Query: 582 ADSSVK 599 D ++K Sbjct: 125 RDKTIK 130 Score = 58.5 bits (140), Expect = 1e-08 Identities = 36/159 (22%), Positives = 72/159 (45%), Gaps = 4/159 (2%) Frame = +3 Query: 126 EFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLW-AVGKPTAVLSLSGLTSPVESLSFDS 302 +FV H SDV +R +++G D+ + +W +G ++ G + V + F Sbjct: 100 QFVGHTSDVLSVSISP-DNRQVVSGSRDKTIKIWNIIGNCKYTITDGGHSDWVSCVRFSP 158 Query: 303 SE---VMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMK 473 + + AG +K+WD+E + + GH +++ P G ASG D + Sbjct: 159 NPDNLTFVSAGWDKA-VKVWDLETFSLRTSHYGHTGYVSAVTISPDGSLCASGGRDGTLM 217 Query: 474 IWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADS 590 +WD+ + +++ + I+ L F+P+ W+ + S Sbjct: 218 LWDLNESTHLYSLEA-KANINALVFSPNRYWLCAATGSS 255 Score = 39.7 bits (91), Expect = 0.007 Identities = 30/108 (27%), Positives = 52/108 (48%), Gaps = 9/108 (8%) Frame = +3 Query: 195 TGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKV 374 +GG D + LW + + T + SL + + +L F + + A S +I+I+D+E + Sbjct: 209 SGGRDGTLMLWDLNESTHLYSLEAKAN-INALVFSPNRYWLCAATGS-SIRIFDLETQEK 266 Query: 375 VRTFT------GHRSN---CASLDSHPFGDFFASGSSDTNMKIWDMRK 491 V T G +S+ C SL P G SG +D +++W + K Sbjct: 267 VDELTVDFVGVGKKSSEPECISLTWSPDGQTLFSGWTDNLIRVWQVTK 314
>SWD3_SCHPO (O43017) Set1 complex component swd3 (Set1C component swd3)| (COMPASS component swd3) (Complex proteins associated with set1 protein swd3) Length = 380 Score = 67.0 bits (162), Expect = 4e-11 Identities = 36/154 (23%), Positives = 65/154 (42%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMI 317 H VTC R + T D + +W+ +L G + + + + + Sbjct: 53 HEKSVTCVSVSPN-KRWIATSSSDGTIKIWSALTFRLECTLFGHYRGISQVKWATGSKYL 111 Query: 318 GAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKR 497 + + TI+IWD E+ VR GH + +S+D +P G SGS D ++IW+++ Sbjct: 112 ASASDDKTIRIWDFEKRCSVRCLKGHTNYVSSIDFNPLGTLLVSGSWDETVRIWNLQDGT 171 Query: 498 CIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 C+ H+ I + + DG + D + Sbjct: 172 CLRMLPAHSEPIISVSISADGTLCATASYDGMAR 205 Score = 61.6 bits (148), Expect = 2e-09 Identities = 33/115 (28%), Positives = 54/115 (46%) Frame = +3 Query: 255 SLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFG 434 +L G V +S ++ I ++ GTIKIW ++ T GH + + Sbjct: 49 TLFGHEKSVTCVSVSPNKRWIATSSSDGTIKIWSALTFRLECTLFGHYRGISQVKWATGS 108 Query: 435 DFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 + AS S D ++IWD K+ + +GHT + + F P G +VSG D +V+ Sbjct: 109 KYLASASDDKTIRIWDFEKRCSVRCLKGHTNYVSSIDFNPLGTLLVSGSWDETVR 163 Score = 60.5 bits (145), Expect = 4e-09 Identities = 32/141 (22%), Positives = 70/141 (49%), Gaps = 1/141 (0%) Frame = +3 Query: 180 SRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDI 359 S+ L + +D+ + +W K +V L G T+ V S+ F+ ++ +G+ T++IW++ Sbjct: 108 SKYLASASDDKTIRIWDFEKRCSVRCLKGHTNYVSSIDFNPLGTLLVSGSWDETVRIWNL 167 Query: 360 EEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHT-YQGHTGRID 536 ++ +R H S+ G A+ S D +IWD+ +C+ T + + Sbjct: 168 QDGTCLRMLPAHSEPIISVSISADGTLCATASYDGMARIWDVLSGQCLKTLVEPINVPLS 227 Query: 537 VLRFTPDGRWIVSGGADSSVK 599 L+FT + ++++ +S ++ Sbjct: 228 NLQFTENRKYLLVSNLNSQIR 248 Score = 29.3 bits (64), Expect = 9.1 Identities = 16/68 (23%), Positives = 28/68 (41%), Gaps = 1/68 (1%) Frame = +3 Query: 195 TGGEDQKVNLWAVGKPTAVLSL-SGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAK 371 T D +W V + +L + P+ +L F + + + I++WD + Sbjct: 197 TASYDGMARIWDVLSGQCLKTLVEPINVPLSNLQFTENRKYLLVSNLNSQIRLWDYRRNR 256 Query: 372 VVRTFTGH 395 VVR F H Sbjct: 257 VVRIFDSH 264
>GBB1_HOMAM (O45040) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 340 Score = 67.0 bits (162), Expect = 4e-11 Identities = 40/139 (28%), Positives = 66/139 (47%), Gaps = 5/139 (3%) Frame = +3 Query: 198 GGEDQKVNLWAV----GKPTAVLSLSGLTSPVESLSF-DSSEVMIGAGAASGTIKIWDIE 362 GG D +++++ G L G T + F D ++++ +G T +WDIE Sbjct: 115 GGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFVDDNQIVTSSGDM--TCALWDIE 172 Query: 363 EAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVL 542 + FTGH + SL P F SG+ D + K+WD+R C T+ GH I+ + Sbjct: 173 TGQQCTQFTGHTGDVMSLSLSPNMRTFTSGACDASAKLWDIRDGMCRQTFPGHESDINAV 232 Query: 543 RFTPDGRWIVSGGADSSVK 599 F P+G +G D++ + Sbjct: 233 TFFPNGHAFATGSDDATCR 251 Score = 66.2 bits (160), Expect = 7e-11 Identities = 39/157 (24%), Positives = 73/157 (46%), Gaps = 2/157 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 +E H ++C +F ++T D LW + +G T V SLS Sbjct: 137 RELPGHTGYLSCCRFVD--DNQIVTSSGDMTCALWDIETGQQCTQFTGHTGDVMSLSLSP 194 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 + +GA + K+WDI + +TF GH S+ ++ P G FA+GS D +++D Sbjct: 195 NMRTFTSGACDASAKLWDIRDGMCRQTFPGHESDINAVTFFPNGHAFATGSDDATCRLFD 254 Query: 483 MR--KKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGAD 587 +R ++ ++++ I + F+ G+ +++G D Sbjct: 255 IRADQELAMYSHDNIICGITSVAFSKSGKLLLAGYDD 291 Score = 43.1 bits (100), Expect = 6e-04 Identities = 30/122 (24%), Positives = 50/122 (40%), Gaps = 2/122 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAV--GKPTAVLSLSGLTSPVESLSF 296 Q F H SD+ F TG +D L+ + + A+ S + + S++F Sbjct: 220 QTFPGHESDINAVTFFPN-GHAFATGSDDATCRLFDIRADQELAMYSHDNIICGITSVAF 278 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 S ++ AG +WD + GH + + L G A+GS D+ +KI Sbjct: 279 SKSGKLLLAGYDDFNCNVWDSMRTERAGVLAGHDNRVSCLGVTEDGMAVATGSWDSFLKI 338 Query: 477 WD 482 W+ Sbjct: 339 WN 340 Score = 30.8 bits (68), Expect = 3.1 Identities = 15/71 (21%), Positives = 27/71 (38%) Frame = +3 Query: 378 RTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPD 557 RT GH + ++ S S D + +WD +H + + + P Sbjct: 49 RTLRGHLAKIYAMHWGSDSRNLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPS 108 Query: 558 GRWIVSGGADS 590 G ++ GG D+ Sbjct: 109 GSYVACGGLDN 119
>GBB1_CAEEL (P17343) Guanine nucleotide-binding protein beta subunit 1| Length = 340 Score = 67.0 bits (162), Expect = 4e-11 Identities = 40/157 (25%), Positives = 73/157 (46%), Gaps = 2/157 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 +E H ++C +F ++T D LW + + +G T V SLS Sbjct: 137 RELPGHTGYLSCCRF--LDDNQIVTSSGDMTCALWDIETGQQCTAFTGHTGDVMSLSLSP 194 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 +GA + K+WDI + +TF GH S+ ++ P G+ FA+GS D +++D Sbjct: 195 DFRTFISGACDASAKLWDIRDGMCKQTFPGHESDINAVAFFPSGNAFATGSDDATCRLFD 254 Query: 483 MR--KKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGAD 587 +R ++ ++++ I + F+ GR + +G D Sbjct: 255 IRADQELAMYSHDNIICGITSVAFSKSGRLLFAGYDD 291 Score = 66.6 bits (161), Expect = 5e-11 Identities = 40/139 (28%), Positives = 65/139 (46%), Gaps = 5/139 (3%) Frame = +3 Query: 198 GGEDQKVNLWAV----GKPTAVLSLSGLTSPVESLSF-DSSEVMIGAGAASGTIKIWDIE 362 GG D +++++ G L G T + F D ++++ +G T +WDIE Sbjct: 115 GGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIVTSSGDM--TCALWDIE 172 Query: 363 EAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVL 542 + FTGH + SL P F SG+ D + K+WD+R C T+ GH I+ + Sbjct: 173 TGQQCTAFTGHTGDVMSLSLSPDFRTFISGACDASAKLWDIRDGMCKQTFPGHESDINAV 232 Query: 543 RFTPDGRWIVSGGADSSVK 599 F P G +G D++ + Sbjct: 233 AFFPSGNAFATGSDDATCR 251 Score = 41.6 bits (96), Expect = 0.002 Identities = 29/122 (23%), Positives = 50/122 (40%), Gaps = 2/122 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAV--GKPTAVLSLSGLTSPVESLSF 296 Q F H SD+ F + TG +D L+ + + A+ S + + S++F Sbjct: 220 QTFPGHESDINAVAFFP-SGNAFATGSDDATCRLFDIRADQELAMYSHDNIICGITSVAF 278 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 S ++ AG +WD + GH + + L G +GS D+ +KI Sbjct: 279 SKSGRLLFAGYDDFNCNVWDSMRQERAGVLAGHDNRVSCLGVTEDGMAVCTGSWDSFLKI 338 Query: 477 WD 482 W+ Sbjct: 339 WN 340 Score = 30.4 bits (67), Expect = 4.1 Identities = 15/71 (21%), Positives = 27/71 (38%) Frame = +3 Query: 378 RTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPD 557 RT GH + ++ S S D + +WD +H + + + P Sbjct: 49 RTLRGHLAKIYAMHWASDSRNLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPS 108 Query: 558 GRWIVSGGADS 590 G ++ GG D+ Sbjct: 109 GSFVACGGLDN 119
>GBB1_CAEBR (Q61ZF6) Guanine nucleotide-binding protein beta subunit 1| Length = 340 Score = 67.0 bits (162), Expect = 4e-11 Identities = 40/157 (25%), Positives = 73/157 (46%), Gaps = 2/157 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 +E H ++C +F ++T D LW + + +G T V SLS Sbjct: 137 RELPGHTGYLSCCRF--LDDNQIVTSSGDMTCALWDIETGQQCTAFTGHTGDVMSLSLSP 194 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 +GA + K+WDI + +TF GH S+ ++ P G+ FA+GS D +++D Sbjct: 195 DFRTFISGACDASAKLWDIRDGMCKQTFPGHESDINAVAFFPSGNAFATGSDDATCRLFD 254 Query: 483 MR--KKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGAD 587 +R ++ ++++ I + F+ GR + +G D Sbjct: 255 IRADQELAMYSHDNIICGITSVAFSKSGRLLFAGYDD 291 Score = 66.6 bits (161), Expect = 5e-11 Identities = 40/139 (28%), Positives = 65/139 (46%), Gaps = 5/139 (3%) Frame = +3 Query: 198 GGEDQKVNLWAV----GKPTAVLSLSGLTSPVESLSF-DSSEVMIGAGAASGTIKIWDIE 362 GG D +++++ G L G T + F D ++++ +G T +WDIE Sbjct: 115 GGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIVTSSGDM--TCALWDIE 172 Query: 363 EAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVL 542 + FTGH + SL P F SG+ D + K+WD+R C T+ GH I+ + Sbjct: 173 TGQQCTAFTGHTGDVMSLSLSPDFRTFISGACDASAKLWDIRDGMCKQTFPGHESDINAV 232 Query: 543 RFTPDGRWIVSGGADSSVK 599 F P G +G D++ + Sbjct: 233 AFFPSGNAFATGSDDATCR 251 Score = 41.6 bits (96), Expect = 0.002 Identities = 29/122 (23%), Positives = 50/122 (40%), Gaps = 2/122 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAV--GKPTAVLSLSGLTSPVESLSF 296 Q F H SD+ F + TG +D L+ + + A+ S + + S++F Sbjct: 220 QTFPGHESDINAVAFFP-SGNAFATGSDDATCRLFDIRADQELAMYSHDNIICGITSVAF 278 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 S ++ AG +WD + GH + + L G +GS D+ +KI Sbjct: 279 SKSGRLLFAGYDDFNCNVWDSMRQERAGVLAGHDNRVSCLGVTEDGMAVCTGSWDSFLKI 338 Query: 477 WD 482 W+ Sbjct: 339 WN 340 Score = 30.4 bits (67), Expect = 4.1 Identities = 15/71 (21%), Positives = 27/71 (38%) Frame = +3 Query: 378 RTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPD 557 RT GH + ++ S S D + +WD +H + + + P Sbjct: 49 RTLRGHLAKIYAMHWASDSRNLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPS 108 Query: 558 GRWIVSGGADS 590 G ++ GG D+ Sbjct: 109 GSFVACGGLDN 119
>WDR48_BRARE (Q6PFM9) WD-repeat protein 48| Length = 677 Score = 67.0 bits (162), Expect = 4e-11 Identities = 41/143 (28%), Positives = 68/143 (47%), Gaps = 9/143 (6%) Frame = +3 Query: 195 TGGEDQKVNLWAVGKPTAVL---------SLSGLTSPVESLSFDSSEVMIGAGAASGTIK 347 + G D+++ LW V TA+ SLSG + SL+ + + +I +G+ ++ Sbjct: 134 SAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQTGTVIISGSTEKVLR 193 Query: 348 IWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTG 527 +WD + GH N SL + G SGSSD +++W + ++RCI TY+ H Sbjct: 194 VWDPRTCAKLMKLKGHTDNVKSLLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDE 253 Query: 528 RIDVLRFTPDGRWIVSGGADSSV 596 + L+ I SGG D + Sbjct: 254 GVWALQVNEAFTHIYSGGRDRKI 276 Score = 57.0 bits (136), Expect = 4e-08 Identities = 32/148 (21%), Positives = 67/148 (45%), Gaps = 9/148 (6%) Frame = +3 Query: 183 RTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIE 362 +TLI+ D V +W K + +L V++L++ + ++ + I +WD+ Sbjct: 88 KTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVN 147 Query: 363 EAKVVR---------TFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQ 515 + + +G++ + SL + G SGS++ +++WD R + + Sbjct: 148 TLTALTASNNTVTTSSLSGNKDSIYSLAMNQTGTVIISGSTEKVLRVWDPRTCAKLMKLK 207 Query: 516 GHTGRIDVLRFTPDGRWIVSGGADSSVK 599 GHT + L DG +SG +D +++ Sbjct: 208 GHTDNVKSLLLNRDGTQCLSGSSDGTIR 235 Score = 44.3 bits (103), Expect = 3e-04 Identities = 23/105 (21%), Positives = 48/105 (45%) Frame = +3 Query: 174 RTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIW 353 +T +I+G ++ + +W ++ L G T V+SL + +G++ GTI++W Sbjct: 178 QTGTVIISGSTEKVLRVWDPRTCAKLMKLKGHTDNVKSLLLNRDGTQCLSGSSDGTIRLW 237 Query: 354 DIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMR 488 + + + + T+ H +L + SG D + D+R Sbjct: 238 SLGQQRCIATYRVHDEGVWALQVNEAFTHIYSGGRDRKIYCTDLR 282 Score = 42.0 bits (97), Expect = 0.001 Identities = 25/109 (22%), Positives = 43/109 (39%), Gaps = 3/109 (2%) Frame = +3 Query: 279 VESLSFDSSEVMIGAGAASGTIKIWDIEEAK---VVRTFTGHRSNCASLDSHPFGDFFAS 449 V +L D + + I+IW + + K + + H + G S Sbjct: 33 VNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDIILCCNGKTLIS 92 Query: 450 GSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 SSDT +K+W+ K C+ T + H + L + D + S G D + Sbjct: 93 ASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQI 141
>KMHB_DICDI (P90648) Myosin heavy chain kinase B (EC 2.7.11.7) (MHCK B)| Length = 732 Score = 67.0 bits (162), Expect = 4e-11 Identities = 36/137 (26%), Positives = 68/137 (49%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L +G D + +W + K + +L G PV ++ + + +G++ TIK+WD++ Sbjct: 515 LFSGSSDHSIKVWDLKKLRCIFTLEGHDKPVHTVLLNDKYLF--SGSSDKTIKVWDLKTL 572 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 + T H +L G + SGS+D +K+WD++ RC +T +GHT + + Sbjct: 573 ECKYTLESHARAVKTLCIS--GQYLFSGSNDKTIKVWDLKTFRCNYTLKGHTKWVTTICI 630 Query: 549 TPDGRWIVSGGADSSVK 599 G + SG D +++ Sbjct: 631 L--GTNLYSGSYDKTIR 645 Score = 53.9 bits (128), Expect = 3e-07 Identities = 27/98 (27%), Positives = 55/98 (56%), Gaps = 2/98 (2%) Frame = +3 Query: 312 MIGAGAASGTIKIWDIEEAKV--VRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDM 485 ++ G + +I+++D + + V+T GH S+ + + SGSSD ++K+WD+ Sbjct: 472 LLFTGCSDNSIRVYDYKSQNMECVQTLKGHEGPVESICYND--QYLFSGSSDHSIKVWDL 529 Query: 486 RKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 +K RCI T +GH + + + +++ SG +D ++K Sbjct: 530 KKLRCIFTLEGHDKPVHTVLL--NDKYLFSGSSDKTIK 565 Score = 52.8 bits (125), Expect = 8e-07 Identities = 33/140 (23%), Positives = 62/140 (44%), Gaps = 3/140 (2%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L +G D+ + +W + +L G T V ++ + + +G+ TI++W+++ Sbjct: 595 LFSGSNDKTIKVWDLKTFRCNYTLKGHTKWVTTICILGTNLY--SGSYDKTIRVWNLKSL 652 Query: 369 KVVRTFTGHR---SNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDV 539 + T GH + D F + S D +KIWD+ RC T +GH + Sbjct: 653 ECSATLRGHDRWVEHMVICDKLLF-----TASDDNTIKIWDLETLRCNTTLEGHNATVQC 707 Query: 540 LRFTPDGRWIVSGGADSSVK 599 L D + ++S D S++ Sbjct: 708 LAVWEDKKCVISCSHDQSIR 727
>YRG5_CAEEL (Q09406) Hypothetical WD-repeat protein K06A1.5| Length = 464 Score = 66.6 bits (161), Expect = 5e-11 Identities = 38/116 (32%), Positives = 58/116 (50%), Gaps = 7/116 (6%) Frame = +3 Query: 186 TLITGGEDQKVNLWAVGK----PTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIW 353 T T G D KV +W V + V +LSG PV L +DS + A + T ++W Sbjct: 188 TFATAGSDSKVQIWRVSPNKTDASKVSTLSGCLGPVNRLDYDSQRHVCLASSNDKTCRLW 247 Query: 354 DIEEAKVVRTFTGHRSNCAS---LDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTY 512 +I+ +++ TF+GH +S SH SGS+D +K WD+ RC+ +Y Sbjct: 248 NIDSQRLLSTFSGHTDKVSSARLFQSHN----VISGSADRTIKNWDISSIRCLKSY 299 Score = 42.0 bits (97), Expect = 0.001 Identities = 29/118 (24%), Positives = 53/118 (44%), Gaps = 4/118 (3%) Frame = +3 Query: 258 LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIE----EAKVVRTFTGHRSNCASLDSH 425 LS V + + S + AG+ S ++IW + +A V T +G LD Sbjct: 171 LSTHDGEVHDVEWMSDDTFATAGSDS-KVQIWRVSPNKTDASKVSTLSGCLGPVNRLDYD 229 Query: 426 PFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 + S+D ++W++ +R + T+ GHT ++ R ++SG AD ++K Sbjct: 230 SQRHVCLASSNDKTCRLWNIDSQRLLSTFSGHTDKVSSARLFQSHN-VISGSADRTIK 286 Score = 41.6 bits (96), Expect = 0.002 Identities = 32/146 (21%), Positives = 70/146 (47%), Gaps = 7/146 (4%) Frame = +3 Query: 159 AKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASG 338 AK G S + I+ D+KV W A S+ L V SL + + A + Sbjct: 310 AKCGVSQS-SFISSHFDKKVRFWDARSSDATYSVE-LGQKVSSLDISMDGLQVLASSRDD 367 Query: 339 TIKIWDIEEAKVVRTFTG--HRSNCASLDS--HPFGDFFASGSSDTNMKIWDMRK---KR 497 T+ + D+ ++ ++ ++++C S + G++ +GSS++++ IW+ + ++ Sbjct: 368 TLSLIDVRNYGIIHLYSAEQYKTSCDSTRAIFSSTGEYVLAGSSNSSVFIWNTKTTKLEK 427 Query: 498 CIHTYQGHTGRIDVLRFTPDGRWIVS 575 + T + + +I L + P GR +++ Sbjct: 428 VVKTARSDSAQIMSLAWNPSGRGLLA 453
>COPB2_MOUSE (O55029) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| (p102) Length = 905 Score = 66.6 bits (161), Expect = 5e-11 Identities = 43/165 (26%), Positives = 74/165 (44%), Gaps = 4/165 (2%) Frame = +3 Query: 117 KLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSL-SGLTSPVESLS 293 ++ F AH+ + C T ++T +D + LW K + + G T V + Sbjct: 91 RVHMFEAHSDYIRCIAVHP-TQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIV 149 Query: 294 FDSSEVMIGAGAA-SGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGD--FFASGSSDT 464 + + A A+ TIK+W + + T GH +D + GD + SG+ D Sbjct: 150 INPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDR 209 Query: 465 NMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 +KIWD + K C+ T +GH + F P+ I++G D +V+ Sbjct: 210 LVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVR 254 Score = 51.2 bits (121), Expect = 2e-06 Identities = 29/121 (23%), Positives = 50/121 (41%), Gaps = 2/121 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 Q F H V + + + D+ + +W +G + +L G V + + S Sbjct: 136 QVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYS 195 Query: 303 S--EVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 + + +GA +KIWD + V+T GH N + HP +GS D ++I Sbjct: 196 GGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRI 255 Query: 477 W 479 W Sbjct: 256 W 256 Score = 48.5 bits (114), Expect = 1e-05 Identities = 32/130 (24%), Positives = 53/130 (40%), Gaps = 2/130 (1%) Frame = +3 Query: 216 VNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGH 395 V +W T V + PV + F + + + GA I++++ + V F H Sbjct: 39 VCVWNHETQTLVKTFEVCDLPVRAAKFVARKNWVVTGADDMQIRVFNYNTLERVHMFEAH 98 Query: 396 RSNCASLDSHPFGDFFASGSSDTNMKIWDMRKK-RCIHTYQGHTGRIDVLRFTP-DGRWI 569 + HP F + S D +K+WD KK C ++GHT + + P D Sbjct: 99 SDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQF 158 Query: 570 VSGGADSSVK 599 S D ++K Sbjct: 159 ASASLDRTIK 168 Score = 30.4 bits (67), Expect = 4.1 Identities = 13/76 (17%), Positives = 32/76 (42%) Frame = +3 Query: 372 VVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFT 551 + R T S+D HP + + + ++ +W+ + + T++ + +F Sbjct: 7 IKRKLTARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFV 66 Query: 552 PDGRWIVSGGADSSVK 599 W+V+G D ++ Sbjct: 67 ARKNWVVTGADDMQIR 82
>COPB2_HUMAN (P35606) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| (p102) Length = 905 Score = 66.6 bits (161), Expect = 5e-11 Identities = 43/165 (26%), Positives = 74/165 (44%), Gaps = 4/165 (2%) Frame = +3 Query: 117 KLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSL-SGLTSPVESLS 293 ++ F AH+ + C T ++T +D + LW K + + G T V + Sbjct: 90 RVHMFEAHSDYIRCIAVHP-TQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIV 148 Query: 294 FDSSEVMIGAGAA-SGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGD--FFASGSSDT 464 + + A A+ TIK+W + + T GH +D + GD + SG+ D Sbjct: 149 INPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDR 208 Query: 465 NMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 +KIWD + K C+ T +GH + F P+ I++G D +V+ Sbjct: 209 LVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVR 253 Score = 51.2 bits (121), Expect = 2e-06 Identities = 29/121 (23%), Positives = 50/121 (41%), Gaps = 2/121 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 Q F H V + + + D+ + +W +G + +L G V + + S Sbjct: 135 QVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYS 194 Query: 303 S--EVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 + + +GA +KIWD + V+T GH N + HP +GS D ++I Sbjct: 195 GGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRI 254 Query: 477 W 479 W Sbjct: 255 W 255 Score = 48.5 bits (114), Expect = 1e-05 Identities = 32/130 (24%), Positives = 53/130 (40%), Gaps = 2/130 (1%) Frame = +3 Query: 216 VNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGH 395 V +W T V + PV + F + + + GA I++++ + V F H Sbjct: 38 VCVWNHETQTLVKTFEVCDLPVRAAKFVARKNWVVTGADDMQIRVFNYNTLERVHMFEAH 97 Query: 396 RSNCASLDSHPFGDFFASGSSDTNMKIWDMRKK-RCIHTYQGHTGRIDVLRFTP-DGRWI 569 + HP F + S D +K+WD KK C ++GHT + + P D Sbjct: 98 SDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQF 157 Query: 570 VSGGADSSVK 599 S D ++K Sbjct: 158 ASASLDRTIK 167 Score = 30.4 bits (67), Expect = 4.1 Identities = 13/76 (17%), Positives = 32/76 (42%) Frame = +3 Query: 372 VVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFT 551 + R T S+D HP + + + ++ +W+ + + T++ + +F Sbjct: 6 IKRKLTARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFV 65 Query: 552 PDGRWIVSGGADSSVK 599 W+V+G D ++ Sbjct: 66 ARKNWVVTGADDMQIR 81
>COPB2_BOVIN (P35605) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| (p102) Length = 905 Score = 66.6 bits (161), Expect = 5e-11 Identities = 43/165 (26%), Positives = 74/165 (44%), Gaps = 4/165 (2%) Frame = +3 Query: 117 KLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSL-SGLTSPVESLS 293 ++ F AH+ + C T ++T +D + LW K + + G T V + Sbjct: 90 RVHMFEAHSDYIRCIAVHP-TQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIV 148 Query: 294 FDSSEVMIGAGAA-SGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGD--FFASGSSDT 464 + + A A+ TIK+W + + T GH +D + GD + SG+ D Sbjct: 149 INPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDR 208 Query: 465 NMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 +KIWD + K C+ T +GH + F P+ I++G D +V+ Sbjct: 209 LVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVR 253 Score = 51.2 bits (121), Expect = 2e-06 Identities = 29/121 (23%), Positives = 50/121 (41%), Gaps = 2/121 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 Q F H V + + + D+ + +W +G + +L G V + + S Sbjct: 135 QVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYS 194 Query: 303 S--EVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 + + +GA +KIWD + V+T GH N + HP +GS D ++I Sbjct: 195 GGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRI 254 Query: 477 W 479 W Sbjct: 255 W 255 Score = 48.5 bits (114), Expect = 1e-05 Identities = 32/130 (24%), Positives = 53/130 (40%), Gaps = 2/130 (1%) Frame = +3 Query: 216 VNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGH 395 V +W T V + PV + F + + + GA I++++ + V F H Sbjct: 38 VCVWNHETQTLVKTFEVCDLPVRAAKFVARKNWVVTGADDMQIRVFNYNTLERVHMFEAH 97 Query: 396 RSNCASLDSHPFGDFFASGSSDTNMKIWDMRKK-RCIHTYQGHTGRIDVLRFTP-DGRWI 569 + HP F + S D +K+WD KK C ++GHT + + P D Sbjct: 98 SDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQF 157 Query: 570 VSGGADSSVK 599 S D ++K Sbjct: 158 ASASLDRTIK 167 Score = 30.4 bits (67), Expect = 4.1 Identities = 13/76 (17%), Positives = 32/76 (42%) Frame = +3 Query: 372 VVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFT 551 + R T S+D HP + + + ++ +W+ + + T++ + +F Sbjct: 6 IKRKLTARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFV 65 Query: 552 PDGRWIVSGGADSSVK 599 W+V+G D ++ Sbjct: 66 ARKNWVVTGADDMQIR 81
>GBLP_NEUCR (Q01369) Guanine nucleotide-binding protein beta subunit-like| protein (Cross-pathway control WD-repeat protein cpc-2) Length = 316 Score = 66.6 bits (161), Expect = 5e-11 Identities = 38/132 (28%), Positives = 62/132 (46%), Gaps = 3/132 (2%) Frame = +3 Query: 207 DQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWD-IEEAKVVRT 383 D+ + LW + T G T+ V S+SF + I +G+ TIK+W+ + + K T Sbjct: 84 DKTLRLWELSTGTTTRRFVGHTNDVLSVSFSADNRQIVSGSRDRTIKLWNTLGDCKFTIT 143 Query: 384 FTGHRS--NCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPD 557 GH +C +P S D +K+W++ + + GHTG I+ + +PD Sbjct: 144 EKGHTEWVSCVRFSPNPQNPVIVSSGWDKLVKVWELSSCKLQTDHIGHTGYINAVTISPD 203 Query: 558 GRWIVSGGADSS 593 G SGG D + Sbjct: 204 GSLCASGGKDGT 215 Score = 60.8 bits (146), Expect = 3e-09 Identities = 37/162 (22%), Positives = 74/162 (45%), Gaps = 4/162 (2%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLW-AVGKPTAVLSLSGLTSPVESLSFD 299 + FV H +DV F +R +++G D+ + LW +G ++ G T V + F Sbjct: 99 RRFVGHTNDVLSVSFSA-DNRQIVSGSRDRTIKLWNTLGDCKFTITEKGHTEWVSCVRFS 157 Query: 300 ---SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNM 470 + V++ +G +K+W++ K+ GH ++ P G ASG D Sbjct: 158 PNPQNPVIVSSGWDK-LVKVWELSSCKLQTDHIGHTGYINAVTISPDGSLCASGGKDGTT 216 Query: 471 KIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 +WD+ + + +++ + I L F+P+ W+ + + S + Sbjct: 217 MLWDLNESKHLYSLNAN-DEIHALVFSPNRYWLCAATSSSII 257 Score = 40.8 bits (94), Expect = 0.003 Identities = 24/101 (23%), Positives = 45/101 (44%), Gaps = 5/101 (4%) Frame = +3 Query: 312 MIGAGAASGTIKIWDIEEAKVV-----RTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 M+ +G+ ++ IW++ + R GH + G + S S D +++ Sbjct: 30 MLLSGSRDKSLIIWNLTRDETSYGYPKRRLHGHSHIVSDCVISSDGAYALSASWDKTLRL 89 Query: 477 WDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 W++ + GHT + + F+ D R IVSG D ++K Sbjct: 90 WELSTGTTTRRFVGHTNDVLSVSFSADNRQIVSGSRDRTIK 130
>TBL1X_HUMAN (O60907) F-box-like/WD-repeat protein TBL1X (Transducin beta-like| 1X protein) (Transducin-beta-like 1, X-linked) (SMAP55) Length = 526 Score = 66.6 bits (161), Expect = 5e-11 Identities = 38/167 (22%), Positives = 76/167 (45%), Gaps = 9/167 (5%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 Q+F H++ + T T + D +++ +G V + G T+ V ++ +D Sbjct: 314 QQFPFHSAPALDVDWQNNT--TFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDP 371 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGD---------FFASGS 455 S +++ + + T+KIW +++ + H ++ P G AS S Sbjct: 372 SGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASAS 431 Query: 456 SDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 D+ +++WD+ + C HT H + + F+PDG+++ SG D V Sbjct: 432 FDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCV 478 Score = 65.1 bits (157), Expect = 1e-10 Identities = 38/168 (22%), Positives = 78/168 (46%), Gaps = 9/168 (5%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 ++ F H ++V K+ + L + +D + +W++ + + L + ++ + Sbjct: 354 VKTFQGHTNEVNAIKWDP-SGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWS 412 Query: 300 ---------SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASG 452 +S +M+ + + T+++WDIE T T H+ S+ P G + ASG Sbjct: 413 PTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASG 472 Query: 453 SSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 S D + IW+ + +H+Y+G TG I + + G + + +D SV Sbjct: 473 SFDKCVHIWNTQSGNLVHSYRG-TGGIFEVCWNARGDKVGASASDGSV 519 Score = 45.4 bits (106), Expect = 1e-04 Identities = 33/137 (24%), Positives = 58/137 (42%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L TG D +W A +L P+ +L ++ I + T IWD Sbjct: 252 LATGSYDGFARIWTEDGNLAS-TLGQHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTG 310 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 + + F H + +D FAS S+D + + + R + T+QGHT ++ +++ Sbjct: 311 EAKQQFPFHSAPALDVDWQN-NTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKW 369 Query: 549 TPDGRWIVSGGADSSVK 599 P G + S D ++K Sbjct: 370 DPSGMLLASCSDDMTLK 386 Score = 37.0 bits (84), Expect = 0.044 Identities = 33/126 (26%), Positives = 53/126 (42%), Gaps = 14/126 (11%) Frame = +3 Query: 258 LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAK-------VVRTFT---GH---- 395 L G S V +++ ++ +G+ T +IW++ E V+R GH Sbjct: 177 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 236 Query: 396 RSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVS 575 + SLD + G A+GS D +IW T H G I L++ G +I+S Sbjct: 237 NKDVTSLDWNTNGTLLATGSYDGFARIW-TEDGNLASTLGQHKGPIFALKWNRKGNYILS 295 Query: 576 GGADSS 593 G D + Sbjct: 296 AGVDKT 301
>NLE1_BOVIN (Q58D20) Notchless homolog 1| Length = 485 Score = 66.2 bits (160), Expect = 7e-11 Identities = 33/138 (23%), Positives = 69/138 (50%), Gaps = 1/138 (0%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLS-LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEE 365 L++G +D + LW+ + L+ ++G + + + F +I + + +IK+WD Sbjct: 344 LVSGSDDFTLFLWSPAEDKKPLARMTGHQALINQVVFSPDSRVIASASFDKSIKLWDGRT 403 Query: 366 AKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLR 545 K + + GH + + SGSSD+ +K+WD++ ++ GH + + Sbjct: 404 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLSTDLPGHADEVYAVD 463 Query: 546 FTPDGRWIVSGGADSSVK 599 ++PDG+ + SGG D ++ Sbjct: 464 WSPDGQRVASGGKDKCLR 481 Score = 63.5 bits (153), Expect = 4e-10 Identities = 45/160 (28%), Positives = 69/160 (43%), Gaps = 6/160 (3%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMI 317 H+ V F T + L +G D V W + T + G V S+S+ + Sbjct: 113 HSEAVISVAFSP-TGKYLASGSGDTTVRFWDLSTETPHFTCQGHRHWVLSISWSPDGKKL 171 Query: 318 GAGAASGTIKIWDIEEAKVV-RTFTGHRSNCASLD-----SHPFGDFFASGSSDTNMKIW 479 +G +G I +WD K V R TGH +L ++P + AS S D ++++W Sbjct: 172 ASGCKNGQILLWDPSTGKQVGRALTGHSKWITALSWEPLHANPECRYVASSSKDGSVRVW 231 Query: 480 DMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 D RC T GH + LR+ DG + S D ++K Sbjct: 232 DTTAGRCERTLTGHAQSVTCLRWGGDG-LLYSASQDRTIK 270 Score = 56.2 bits (134), Expect = 7e-08 Identities = 26/100 (26%), Positives = 50/100 (50%) Frame = +3 Query: 180 SRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDI 359 SR + + D+ + LW + SL G + V +++ + ++ +G++ T+K+WD+ Sbjct: 384 SRVIASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDV 443 Query: 360 EEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 + K+ GH ++D P G ASG D ++IW Sbjct: 444 KAQKLSTDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 483 Score = 49.3 bits (116), Expect = 8e-06 Identities = 33/121 (27%), Positives = 54/121 (44%), Gaps = 6/121 (4%) Frame = +3 Query: 255 SLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFG 434 SL G + V S++F + + +G+ T++ WD+ T GHR S+ P G Sbjct: 109 SLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCQGHRHWVLSISWSPDG 168 Query: 435 DFFASGSSDTNMKIWD-MRKKRCIHTYQGHTGRIDVLRF-----TPDGRWIVSGGADSSV 596 ASG + + +WD K+ GH+ I L + P+ R++ S D SV Sbjct: 169 KKLASGCKNGQILLWDPSTGKQVGRALTGHSKWITALSWEPLHANPECRYVASSSKDGSV 228 Query: 597 K 599 + Sbjct: 229 R 229 Score = 43.5 bits (101), Expect = 5e-04 Identities = 30/132 (22%), Positives = 60/132 (45%), Gaps = 7/132 (5%) Frame = +3 Query: 183 RTLITGGEDQKVNLW--AVGKPTAVLSLSGLTSPVESLSFDSSEV-----MIGAGAASGT 341 + L +G ++ ++ LW + GK +L+G + + +LS++ + + + G+ Sbjct: 169 KKLASGCKNGQILLWDPSTGKQVG-RALTGHSKWITALSWEPLHANPECRYVASSSKDGS 227 Query: 342 IKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGH 521 +++WD + RT TGH + L G + S S D +K+W T QGH Sbjct: 228 VRVWDTTAGRCERTLTGHAQSVTCLRWGGDGLLY-SASQDRTIKVWRAHDGVLCRTLQGH 286 Query: 522 TGRIDVLRFTPD 557 ++ + + D Sbjct: 287 GHWVNTMALSTD 298 Score = 32.7 bits (73), Expect = 0.82 Identities = 11/35 (31%), Positives = 23/35 (65%) Frame = +3 Query: 495 RCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 RC + +GH+ + + F+P G+++ SG D++V+ Sbjct: 105 RCTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVR 139
>GBLP_DROME (O18640) Guanine nucleotide-binding protein beta subunit-like| protein (Receptor of activated protein kinase C homolog) Length = 318 Score = 66.2 bits (160), Expect = 7e-11 Identities = 44/165 (26%), Positives = 71/165 (43%), Gaps = 3/165 (1%) Frame = +3 Query: 105 KRAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVE 284 KR Y F+ SDV + G ++G DQ + LW + G T V Sbjct: 58 KRLYGHSHFI---SDVVLSSDGNYA----LSGSWDQTLRLWDLAAGKTTRRFEGHTKDVL 110 Query: 285 SLSFDSSEVMIGAGAASGTIKIWD-IEEAKVVRTFTGHRS--NCASLDSHPFGDFFASGS 455 S++F + I +G+ TIK+W+ + E K GH +C + S Sbjct: 111 SVAFSADNRQIVSGSRDKTIKLWNTLAECKFTIQEDGHTDWVSCVRFSPNHSNPIIVSCG 170 Query: 456 SDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADS 590 D +K+W++ + + + GH G ++ + +PDG SGG DS Sbjct: 171 WDRTVKVWNLANCKLKNNHHGHNGYLNTVTVSPDGSLCTSGGKDS 215 Score = 59.7 bits (143), Expect = 6e-09 Identities = 36/153 (23%), Positives = 69/153 (45%), Gaps = 4/153 (2%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLW-AVGKPTAVLSLSGLTSPVESLSFD 299 + F H DV F +R +++G D+ + LW + + + G T V + F Sbjct: 100 RRFEGHTKDVLSVAFSA-DNRQIVSGSRDKTIKLWNTLAECKFTIQEDGHTDWVSCVRFS 158 Query: 300 ---SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNM 470 S+ +++ G T+K+W++ K+ GH ++ P G SG D+ Sbjct: 159 PNHSNPIIVSCGW-DRTVKVWNLANCKLKNNHHGHNGYLNTVTVSPDGSLCTSGGKDSKA 217 Query: 471 KIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWI 569 +WD+ + ++T + H I+ L F+P+ W+ Sbjct: 218 LLWDLNDGKNLYTLE-HNDIINALCFSPNRYWL 249 Score = 45.8 bits (107), Expect = 9e-05 Identities = 19/56 (33%), Positives = 33/56 (58%) Frame = +3 Query: 432 GDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 G++ SGS D +++WD+ + ++GHT + + F+ D R IVSG D ++K Sbjct: 76 GNYALSGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIK 131 Score = 33.1 bits (74), Expect = 0.63 Identities = 26/106 (24%), Positives = 43/106 (40%), Gaps = 9/106 (8%) Frame = +3 Query: 195 TGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKV 374 +GG+D K LW + + +L + +L F + + A +IKIWD+ K Sbjct: 210 SGGKDSKALLWDLNDGKNLYTLEH-NDIINALCFSPNRYWLCV-AYGPSIKIWDLACKKT 267 Query: 375 VR---------TFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDM 485 V T + C SL G +G SD +++W + Sbjct: 268 VEELRPEVVSPTSKADQPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 313
>GBB4_RAT (O35353) Guanine nucleotide-binding protein beta subunit 4| (Transducin beta chain 4) Length = 339 Score = 66.2 bits (160), Expect = 7e-11 Identities = 32/101 (31%), Positives = 51/101 (50%) Frame = +3 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 D +++ +G T +WDIE + TFTGH + SL P F SG+ D + K+ Sbjct: 152 DDGQIITSSGDT--TCALWDIETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSKL 209 Query: 477 WDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 WD+R C ++ GH I+ + F P G +G D++ + Sbjct: 210 WDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCR 250 Score = 65.1 bits (157), Expect = 1e-10 Identities = 40/157 (25%), Positives = 74/157 (47%), Gaps = 2/157 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 +E H ++C +F +IT D LW + + +G + V SLS Sbjct: 136 RELPGHTGYLSCCRF--LDDGQIITSSGDTTCALWDIETGQQTTTFTGHSGDVMSLSLSP 193 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 +GA + K+WDI + ++FTGH S+ ++ P G FA+GS D +++D Sbjct: 194 DLKTFVSGACDASSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFD 253 Query: 483 MR--KKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGAD 587 +R ++ ++++ I + F+ GR +++G D Sbjct: 254 LRADQELLLYSHDNIICGITSVAFSKSGRLLLAGYDD 290 Score = 40.0 bits (92), Expect = 0.005 Identities = 29/122 (23%), Positives = 50/122 (40%), Gaps = 2/122 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLS--GLTSPVESLSF 296 Q F H SD+ F + TG +D L+ + +L S + + S++F Sbjct: 219 QSFTGHISDINAVSFFP-SGYAFATGSDDATCRLFDLRADQELLLYSHDNIICGITSVAF 277 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 S ++ AG +WD + GH + + L G A+GS D+ ++I Sbjct: 278 SKSGRLLLAGYDDFNCSVWDALKGGRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRI 337 Query: 477 WD 482 W+ Sbjct: 338 WN 339 Score = 31.2 bits (69), Expect = 2.4 Identities = 16/71 (22%), Positives = 27/71 (38%) Frame = +3 Query: 378 RTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPD 557 RT GH + ++ S S D + IWD +H + + + P Sbjct: 48 RTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPS 107 Query: 558 GRWIVSGGADS 590 G ++ GG D+ Sbjct: 108 GNYVACGGLDN 118
>GBB4_MOUSE (P29387) Guanine nucleotide-binding protein beta subunit 4| (Transducin beta chain 4) Length = 339 Score = 66.2 bits (160), Expect = 7e-11 Identities = 32/101 (31%), Positives = 51/101 (50%) Frame = +3 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 D +++ +G T +WDIE + TFTGH + SL P F SG+ D + K+ Sbjct: 152 DDGQIITSSGDT--TCALWDIETGQQTTTFTGHSGDVMSLSLSPDLKTFVSGACDASSKL 209 Query: 477 WDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 WD+R C ++ GH I+ + F P G +G D++ + Sbjct: 210 WDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCR 250 Score = 65.1 bits (157), Expect = 1e-10 Identities = 40/157 (25%), Positives = 74/157 (47%), Gaps = 2/157 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 +E H ++C +F +IT D LW + + +G + V SLS Sbjct: 136 RELPGHTGYLSCCRF--LDDGQIITSSGDTTCALWDIETGQQTTTFTGHSGDVMSLSLSP 193 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 +GA + K+WDI + ++FTGH S+ ++ P G FA+GS D +++D Sbjct: 194 DLKTFVSGACDASSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFD 253 Query: 483 MR--KKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGAD 587 +R ++ ++++ I + F+ GR +++G D Sbjct: 254 LRADQELLLYSHDNIICGITSVAFSKSGRLLLAGYDD 290 Score = 39.3 bits (90), Expect = 0.009 Identities = 29/122 (23%), Positives = 50/122 (40%), Gaps = 2/122 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLS--GLTSPVESLSF 296 Q F H SD+ F + TG +D L+ + +L S + + S++F Sbjct: 219 QSFTGHISDINAVSFFP-SGYAFATGSDDATCRLFDLRADQELLLYSHDNIICGITSVAF 277 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 S ++ AG +WD + GH + + L G A+GS D+ ++I Sbjct: 278 SKSGRLLLAGYDDFNCSVWDALKGGRSGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRI 337 Query: 477 WD 482 W+ Sbjct: 338 WN 339 Score = 31.2 bits (69), Expect = 2.4 Identities = 16/71 (22%), Positives = 27/71 (38%) Frame = +3 Query: 378 RTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPD 557 RT GH + ++ S S D + IWD +H + + + P Sbjct: 48 RTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPS 107 Query: 558 GRWIVSGGADS 590 G ++ GG D+ Sbjct: 108 GNYVACGGLDN 118
>TLE1_MOUSE (Q62440) Transducin-like enhancer protein 1 (Groucho-related| protein 1) (Grg-1) Length = 770 Score = 66.2 bits (160), Expect = 7e-11 Identities = 37/140 (26%), Positives = 65/140 (46%), Gaps = 2/140 (1%) Frame = +3 Query: 186 TLITGGEDQKVNLWAVGKPTAVLS--LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDI 359 TLI GGE +++W + PT + L+ +L+ + + + G I +WD+ Sbjct: 544 TLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDL 603 Query: 360 EEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDV 539 +VR F GH + +D G +G D ++ WD+R+ R + + T +I Sbjct: 604 HNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHD-FTSQIFS 662 Query: 540 LRFTPDGRWIVSGGADSSVK 599 L + P G W+ G S+V+ Sbjct: 663 LGYCPTGEWLAVGMESSNVE 682 Score = 55.1 bits (131), Expect = 2e-07 Identities = 41/165 (24%), Positives = 69/165 (41%), Gaps = 14/165 (8%) Frame = +3 Query: 147 DVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGA- 323 +V CA +R + TGG+ V +W + P G SPV L + + I + Sbjct: 485 EVVCAVTISNPTRHVYTGGKGC-VKVWDISHP-------GNKSPVSQLDCLNRDNYIRSC 536 Query: 324 -----------GAASGTIKIWDIEEA--KVVRTFTGHRSNCASLDSHPFGDFFASGSSDT 464 G + T+ IWD+ ++ T C +L P S SD Sbjct: 537 KLLPDGCTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDG 596 Query: 465 NMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 N+ +WD+ + + +QGHT + + DG + +GG D++V+ Sbjct: 597 NIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVR 641
>TLE1_HUMAN (Q04724) Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog)| Length = 770 Score = 66.2 bits (160), Expect = 7e-11 Identities = 37/140 (26%), Positives = 65/140 (46%), Gaps = 2/140 (1%) Frame = +3 Query: 186 TLITGGEDQKVNLWAVGKPTAVLS--LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDI 359 TLI GGE +++W + PT + L+ +L+ + + + G I +WD+ Sbjct: 544 TLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDL 603 Query: 360 EEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDV 539 +VR F GH + +D G +G D ++ WD+R+ R + + T +I Sbjct: 604 HNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHD-FTSQIFS 662 Query: 540 LRFTPDGRWIVSGGADSSVK 599 L + P G W+ G S+V+ Sbjct: 663 LGYCPTGEWLAVGMESSNVE 682 Score = 55.1 bits (131), Expect = 2e-07 Identities = 41/165 (24%), Positives = 69/165 (41%), Gaps = 14/165 (8%) Frame = +3 Query: 147 DVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGA- 323 +V CA +R + TGG+ V +W + P G SPV L + + I + Sbjct: 485 EVVCAVTISNPTRHVYTGGKGC-VKVWDISHP-------GNKSPVSQLDCLNRDNYIRSC 536 Query: 324 -----------GAASGTIKIWDIEEA--KVVRTFTGHRSNCASLDSHPFGDFFASGSSDT 464 G + T+ IWD+ ++ T C +L P S SD Sbjct: 537 KLLPDGCTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDG 596 Query: 465 NMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 N+ +WD+ + + +QGHT + + DG + +GG D++V+ Sbjct: 597 NIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVR 641
>NLE1_PONPY (Q5RFF8) Notchless homolog 1| Length = 484 Score = 66.2 bits (160), Expect = 7e-11 Identities = 32/138 (23%), Positives = 69/138 (50%), Gaps = 1/138 (0%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLS-LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEE 365 L++G +D + LW+ + L+ ++G + + + F ++ + + +IK+WD Sbjct: 343 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 402 Query: 366 AKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLR 545 K + + GH + + SGSSD+ +K+WD++ ++ GH + + Sbjct: 403 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVD 462 Query: 546 FTPDGRWIVSGGADSSVK 599 ++PDG+ + SGG D ++ Sbjct: 463 WSPDGQRVASGGKDKCLR 480 Score = 63.5 bits (153), Expect = 4e-10 Identities = 46/160 (28%), Positives = 69/160 (43%), Gaps = 6/160 (3%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMI 317 H+ V F T + L +G D V W + T + G V S+S+ + Sbjct: 112 HSEAVISVAFSP-TGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGKKL 170 Query: 318 GAGAASGTIKIWDIEEAKVV-RTFTGHRS-----NCASLDSHPFGDFFASGSSDTNMKIW 479 +G +G I +WD K V RT GH + L ++P + AS S D +++IW Sbjct: 171 ASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIW 230 Query: 480 DMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 D RC GHT + LR+ DG + S D ++K Sbjct: 231 DTTAGRCERILTGHTQSVTCLRWGGDG-LLYSASQDRTIK 269 Score = 56.2 bits (134), Expect = 7e-08 Identities = 26/100 (26%), Positives = 50/100 (50%) Frame = +3 Query: 180 SRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDI 359 SR + + D+ + LW + SL G + V +++ + ++ +G++ T+K+WD+ Sbjct: 383 SRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDV 442 Query: 360 EEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 + K+ GH ++D P G ASG D ++IW Sbjct: 443 KAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 482 Score = 50.8 bits (120), Expect = 3e-06 Identities = 34/121 (28%), Positives = 55/121 (45%), Gaps = 6/121 (4%) Frame = +3 Query: 255 SLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFG 434 SL G + V S++F + + +G+ T++ WD+ T GHR S+ P G Sbjct: 108 SLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDG 167 Query: 435 DFFASGSSDTNMKIWD-MRKKRCIHTYQGHTGRI-----DVLRFTPDGRWIVSGGADSSV 596 ASG + + +WD K+ T GH+ I + L P+ R++ S D SV Sbjct: 168 KKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSV 227 Query: 597 K 599 + Sbjct: 228 R 228 Score = 45.8 bits (107), Expect = 9e-05 Identities = 26/107 (24%), Positives = 51/107 (47%) Frame = +3 Query: 258 LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGD 437 +S L +ES + ++ +V+ ++ + + + GH S+ P G Sbjct: 69 ISSLGKTLESQAVETEKVLDIIYQPQAIFRVRAV--TRCTSSLEGHSEAVISVAFSPTGK 126 Query: 438 FFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSG 578 + ASGS DT ++ WD+ + T +GH + + ++PDG+ + SG Sbjct: 127 YLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGKKLASG 173 Score = 41.2 bits (95), Expect = 0.002 Identities = 30/132 (22%), Positives = 58/132 (43%), Gaps = 7/132 (5%) Frame = +3 Query: 183 RTLITGGEDQKVNLW--AVGKPTAVLSLSGLTSPVESLSFDSSEV-----MIGAGAASGT 341 + L +G ++ ++ LW + GK +L+G + + LS++ + + + G+ Sbjct: 168 KKLASGCKNGQILLWDPSTGKQVG-RTLAGHSKWITGLSWEPLHANPECRYVASSSKDGS 226 Query: 342 IKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGH 521 ++IWD + R TGH + L G + S S D +K+W T QGH Sbjct: 227 VRIWDTTAGRCERILTGHTQSVTCLRWGGDGLLY-SASQDRTIKVWRAHDGVLCRTLQGH 285 Query: 522 TGRIDVLRFTPD 557 ++ + + D Sbjct: 286 GHWVNTMALSTD 297 Score = 32.7 bits (73), Expect = 0.82 Identities = 11/35 (31%), Positives = 23/35 (65%) Frame = +3 Query: 495 RCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 RC + +GH+ + + F+P G+++ SG D++V+ Sbjct: 104 RCTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVR 138
>NLE1_MOUSE (Q8VEJ4) Notchless homolog 1| Length = 484 Score = 66.2 bits (160), Expect = 7e-11 Identities = 32/138 (23%), Positives = 69/138 (50%), Gaps = 1/138 (0%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLS-LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEE 365 L++G +D + LW+ + L+ ++G + + + F ++ + + +IK+WD Sbjct: 343 LVSGSDDFTLFLWSPAEDKKPLARMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 402 Query: 366 AKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLR 545 K + + GH + + SGSSD+ +K+WD++ ++ GH + + Sbjct: 403 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLATDLPGHADEVYAVD 462 Query: 546 FTPDGRWIVSGGADSSVK 599 ++PDG+ + SGG D ++ Sbjct: 463 WSPDGQRVASGGKDKCLR 480 Score = 62.4 bits (150), Expect = 1e-09 Identities = 45/160 (28%), Positives = 67/160 (41%), Gaps = 6/160 (3%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMI 317 H+ V F T + L +G D V W + T + G V S+S+ + Sbjct: 112 HSEAVISVAFSP-TGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGKKL 170 Query: 318 GAGAASGTIKIWDIEEA-KVVRTFTGHRSNCASLDSHPFG-----DFFASGSSDTNMKIW 479 +G +G I +WD +V RT TGH L P + AS S D ++++W Sbjct: 171 ASGCKNGQILLWDPSTGLQVGRTLTGHSKWITGLSWEPLHMNPECRYVASSSKDGSVRVW 230 Query: 480 DMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 D RC GHT + LR+ DG + S D ++K Sbjct: 231 DTTAGRCERILTGHTQSVTCLRWGGDG-LLYSASQDRTIK 269 Score = 56.2 bits (134), Expect = 7e-08 Identities = 26/100 (26%), Positives = 50/100 (50%) Frame = +3 Query: 180 SRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDI 359 SR + + D+ + LW + SL G + V +++ + ++ +G++ T+K+WD+ Sbjct: 383 SRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDV 442 Query: 360 EEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 + K+ GH ++D P G ASG D ++IW Sbjct: 443 KAQKLATDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 482 Score = 49.7 bits (117), Expect = 6e-06 Identities = 33/121 (27%), Positives = 54/121 (44%), Gaps = 6/121 (4%) Frame = +3 Query: 255 SLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFG 434 SL G + V S++F + + +G+ T++ WD+ T GHR S+ P G Sbjct: 108 SLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDG 167 Query: 435 DFFASGSSDTNMKIWDMRKKRCI-HTYQGHTGRI-----DVLRFTPDGRWIVSGGADSSV 596 ASG + + +WD + T GH+ I + L P+ R++ S D SV Sbjct: 168 KKLASGCKNGQILLWDPSTGLQVGRTLTGHSKWITGLSWEPLHMNPECRYVASSSKDGSV 227 Query: 597 K 599 + Sbjct: 228 R 228 Score = 46.2 bits (108), Expect = 7e-05 Identities = 26/107 (24%), Positives = 51/107 (47%) Frame = +3 Query: 258 LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGD 437 +S L +ES S ++ +++ ++ + + + GH S+ P G Sbjct: 69 VSSLGKTLESQSVETEKIVDIIYQPQAVFRVRAV--TRCTSSLEGHSEAVISVAFSPTGK 126 Query: 438 FFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSG 578 + ASGS DT ++ WD+ + T +GH + + ++PDG+ + SG Sbjct: 127 YLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGKKLASG 173 Score = 40.0 bits (92), Expect = 0.005 Identities = 28/131 (21%), Positives = 57/131 (43%), Gaps = 6/131 (4%) Frame = +3 Query: 183 RTLITGGEDQKVNLWAVGKPTAV-LSLSGLTSPVESLSFDSSEV-----MIGAGAASGTI 344 + L +G ++ ++ LW V +L+G + + LS++ + + + + G++ Sbjct: 168 KKLASGCKNGQILLWDPSTGLQVGRTLTGHSKWITGLSWEPLHMNPECRYVASSSKDGSV 227 Query: 345 KIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHT 524 ++WD + R TGH + L G + S S D +K+W T QGH Sbjct: 228 RVWDTTAGRCERILTGHTQSVTCLRWGGDGLLY-SASQDRTIKVWRAHDGVLCRTLQGHG 286 Query: 525 GRIDVLRFTPD 557 ++ + + D Sbjct: 287 HWVNTMALSTD 297 Score = 32.7 bits (73), Expect = 0.82 Identities = 11/35 (31%), Positives = 23/35 (65%) Frame = +3 Query: 495 RCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 RC + +GH+ + + F+P G+++ SG D++V+ Sbjct: 104 RCTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVR 138
>NLE1_HUMAN (Q9NVX2) Notchless homolog 1| Length = 484 Score = 66.2 bits (160), Expect = 7e-11 Identities = 32/138 (23%), Positives = 69/138 (50%), Gaps = 1/138 (0%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLS-LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEE 365 L++G +D + LW+ + L+ ++G + + + F ++ + + +IK+WD Sbjct: 343 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 402 Query: 366 AKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLR 545 K + + GH + + SGSSD+ +K+WD++ ++ GH + + Sbjct: 403 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVD 462 Query: 546 FTPDGRWIVSGGADSSVK 599 ++PDG+ + SGG D ++ Sbjct: 463 WSPDGQRVASGGKDKCLR 480 Score = 63.5 bits (153), Expect = 4e-10 Identities = 46/160 (28%), Positives = 69/160 (43%), Gaps = 6/160 (3%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMI 317 H+ V F T + L +G D V W + T + G V S+S+ + Sbjct: 112 HSEAVISVAFSP-TGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGKKL 170 Query: 318 GAGAASGTIKIWDIEEAKVV-RTFTGHRS-----NCASLDSHPFGDFFASGSSDTNMKIW 479 +G +G I +WD K V RT GH + L ++P + AS S D +++IW Sbjct: 171 ASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIW 230 Query: 480 DMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 D RC GHT + LR+ DG + S D ++K Sbjct: 231 DTTAGRCERILTGHTQSVTCLRWGGDG-LLYSASQDRTIK 269 Score = 56.2 bits (134), Expect = 7e-08 Identities = 26/100 (26%), Positives = 50/100 (50%) Frame = +3 Query: 180 SRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDI 359 SR + + D+ + LW + SL G + V +++ + ++ +G++ T+K+WD+ Sbjct: 383 SRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDV 442 Query: 360 EEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 + K+ GH ++D P G ASG D ++IW Sbjct: 443 KAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 482 Score = 50.8 bits (120), Expect = 3e-06 Identities = 34/121 (28%), Positives = 55/121 (45%), Gaps = 6/121 (4%) Frame = +3 Query: 255 SLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFG 434 SL G + V S++F + + +G+ T++ WD+ T GHR S+ P G Sbjct: 108 SLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDG 167 Query: 435 DFFASGSSDTNMKIWD-MRKKRCIHTYQGHTGRI-----DVLRFTPDGRWIVSGGADSSV 596 ASG + + +WD K+ T GH+ I + L P+ R++ S D SV Sbjct: 168 KKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSV 227 Query: 597 K 599 + Sbjct: 228 R 228 Score = 41.2 bits (95), Expect = 0.002 Identities = 30/132 (22%), Positives = 58/132 (43%), Gaps = 7/132 (5%) Frame = +3 Query: 183 RTLITGGEDQKVNLW--AVGKPTAVLSLSGLTSPVESLSFDSSEV-----MIGAGAASGT 341 + L +G ++ ++ LW + GK +L+G + + LS++ + + + G+ Sbjct: 168 KKLASGCKNGQILLWDPSTGKQVG-RTLAGHSKWITGLSWEPLHANPECRYVASSSKDGS 226 Query: 342 IKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGH 521 ++IWD + R TGH + L G + S S D +K+W T QGH Sbjct: 227 VRIWDTTAGRCERILTGHTQSVTCLRWGGDGLLY-SASQDRTIKVWRAHDGVLCRTLQGH 285 Query: 522 TGRIDVLRFTPD 557 ++ + + D Sbjct: 286 GHWVNTMALSTD 297 Score = 32.7 bits (73), Expect = 0.82 Identities = 11/35 (31%), Positives = 23/35 (65%) Frame = +3 Query: 495 RCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 RC + +GH+ + + F+P G+++ SG D++V+ Sbjct: 104 RCTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVR 138
>EBI_DROME (Q95RJ9) F-box-like/WD repeat protein ebi| Length = 700 Score = 66.2 bits (160), Expect = 7e-11 Identities = 37/167 (22%), Positives = 76/167 (45%), Gaps = 9/167 (5%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 Q+F H++ + +T++ + DQ++++ +G + + G T+ V ++ + Sbjct: 487 QQFAFHSAPALDVDW--QTNQAFASCSTDQRIHVCRLGVNEPIKTFKGHTNEVNAIKWCP 544 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGD---------FFASGS 455 ++ + + T+KIW + + H ++ P G AS S Sbjct: 545 QGQLLASCSDDMTLKIWSMNRDRCCHDLQAHSKEIYTIKWSPTGPGTNNPNTNLILASAS 604 Query: 456 SDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 D+ +++WD+ + CIHT HT + + F+PDG+ + SG D V Sbjct: 605 FDSTVRLWDVERGSCIHTLTKHTEPVYSVAFSPDGKHLASGSFDKCV 651 Score = 61.2 bits (147), Expect = 2e-09 Identities = 35/168 (20%), Positives = 78/168 (46%), Gaps = 9/168 (5%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 ++ F H ++V K+ + + L + +D + +W++ + L + + ++ + Sbjct: 527 IKTFKGHTNEVNAIKWCPQ-GQLLASCSDDMTLKIWSMNRDRCCHDLQAHSKEIYTIKWS 585 Query: 300 ---------SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASG 452 ++ +++ + + T+++WD+E + T T H S+ P G ASG Sbjct: 586 PTGPGTNNPNTNLILASASFDSTVRLWDVERGSCIHTLTKHTEPVYSVAFSPDGKHLASG 645 Query: 453 SSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 S D + IW + + +H+Y+G TG I + + G + + +D SV Sbjct: 646 SFDKCVHIWSTQTGQLVHSYKG-TGGIFEVCWNSKGTKVGASASDGSV 692 Score = 47.4 bits (111), Expect = 3e-05 Identities = 32/137 (23%), Positives = 58/137 (42%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L TG D +W A +L P+ +L ++ I + T IWD Sbjct: 425 LATGSYDGYARIWKTDGRLAS-TLGQHKGPIFALKWNKCGNYILSAGVDKTTIIWDASTG 483 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 + + F H + +D FAS S+D + + + I T++GHT ++ +++ Sbjct: 484 QCTQQFAFHSAPALDVDWQT-NQAFASCSTDQRIHVCRLGVNEPIKTFKGHTNEVNAIKW 542 Query: 549 TPDGRWIVSGGADSSVK 599 P G+ + S D ++K Sbjct: 543 CPQGQLLASCSDDMTLK 559 Score = 42.0 bits (97), Expect = 0.001 Identities = 34/125 (27%), Positives = 54/125 (43%), Gaps = 13/125 (10%) Frame = +3 Query: 258 LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAK------VVR-------TFTGHR 398 L G S V +++ S ++ +G+ T +IWD+ +A V+R Sbjct: 351 LRGHESEVFICAWNPSRDLLASGSGDSTARIWDMSDANTNSNQLVLRHCIQKGGAEVPSN 410 Query: 399 SNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSG 578 + SLD + G A+GS D +IW R T H G I L++ G +I+S Sbjct: 411 KDVTSLDWNCDGSLLATGSYDGYARIW-KTDGRLASTLGQHKGPIFALKWNKCGNYILSA 469 Query: 579 GADSS 593 G D + Sbjct: 470 GVDKT 474 Score = 35.4 bits (80), Expect = 0.13 Identities = 23/67 (34%), Positives = 30/67 (44%), Gaps = 5/67 (7%) Frame = +3 Query: 300 SSEVMIGAGAASGTIKIWDIEE-----AKVVRTFTGHRSNCASLDSHPFGDFFASGSSDT 464 SS GAG + + + DI+E R GH S +P D ASGS D+ Sbjct: 319 SSSTSGGAGTPAALVPM-DIDENIEIPESKARVLRGHESEVFICAWNPSRDLLASGSGDS 377 Query: 465 NMKIWDM 485 +IWDM Sbjct: 378 TARIWDM 384
>PWP2_NEUCR (Q9C270) Periodic tryptophan protein 2 homolog| Length = 899 Score = 66.2 bits (160), Expect = 7e-11 Identities = 35/139 (25%), Positives = 70/139 (50%), Gaps = 2/139 (1%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 ++T +D K+ +W +++ + TS + + F ++ + G+I+ WD+ Sbjct: 354 IVTVADDGKIKVWDTESGFCIVTFTEHTSGITACEFSKKGNVLFTSSLDGSIRAWDLIRY 413 Query: 369 KVVRTFTG-HRSNCASLDSHPFGDFFASGSSDT-NMKIWDMRKKRCIHTYQGHTGRIDVL 542 + RTFT R + + + P G+ A+GS D+ ++ IW ++ + + GH G + L Sbjct: 414 RNFRTFTAPERLSFSCMAVDPSGEIVAAGSVDSFDIHIWSVQTGQLLDRLSGHEGPVSSL 473 Query: 543 RFTPDGRWIVSGGADSSVK 599 F P+G +VSG D + + Sbjct: 474 AFAPNGGLLVSGSWDRTAR 492 Score = 55.8 bits (133), Expect = 9e-08 Identities = 36/158 (22%), Positives = 70/158 (44%), Gaps = 1/158 (0%) Frame = +3 Query: 129 FVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSE 308 F+ +++ V CA F S L+ G + L+ + + +LS + ++ ++ + S Sbjct: 250 FMQNSATVRCAAFHPE-SNLLVAGFSNGIFGLYEMPDFNMIHTLSISQNEIDFVTINKSG 308 Query: 309 VMIGAGAAS-GTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDM 485 + GA+ G + +W+ + + GH + SL P G + + D +K+WD Sbjct: 309 EWLAFGASKLGQLLVWEWQSESYILKQQGHFDSMNSLVYSPDGQRIVTVADDGKIKVWDT 368 Query: 486 RKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 CI T+ HT I F+ G + + D S++ Sbjct: 369 ESGFCIVTFTEHTSGITACEFSKKGNVLFTSSLDGSIR 406 Score = 52.8 bits (125), Expect = 8e-07 Identities = 42/172 (24%), Positives = 72/172 (41%), Gaps = 7/172 (4%) Frame = +3 Query: 102 TKRAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPV 281 T+ + + F H S +T +F K+ L T D + W + + + T+P Sbjct: 368 TESGFCIVTFTEHTSGITACEFSKK-GNVLFTSSLDGSIRAWDLIR---YRNFRTFTAP- 422 Query: 282 ESLSFD------SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFF 443 E LSF S E++ S I IW ++ +++ +GH +SL P G Sbjct: 423 ERLSFSCMAVDPSGEIVAAGSVDSFDIHIWSVQTGQLLDRLSGHEGPVSSLAFAPNGGLL 482 Query: 444 ASGSSDTNMKIWDM-RKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 SGS D +IW + + + Q ++ +D+ F PD I D ++ Sbjct: 483 VSGSWDRTARIWSIFNRTQTSEPLQLNSDVLDI-AFRPDSLQIAISTLDGNL 533 Score = 48.9 bits (115), Expect = 1e-05 Identities = 30/124 (24%), Positives = 50/124 (40%), Gaps = 1/124 (0%) Frame = +3 Query: 222 LWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRS 401 +W + +L G + SL + I A G IK+WD E + TFT H S Sbjct: 323 VWEWQSESYILKQQGHFDSMNSLVYSPDGQRIVTVADDGKIKVWDTESGFCIVTFTEHTS 382 Query: 402 NCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQG-HTGRIDVLRFTPDGRWIVSG 578 + + G+ + S D +++ WD+ + R T+ + P G + +G Sbjct: 383 GITACEFSKKGNVLFTSSLDGSIRAWDLIRYRNFRTFTAPERLSFSCMAVDPSGEIVAAG 442 Query: 579 GADS 590 DS Sbjct: 443 SVDS 446
>GBB2_DROME (P29829) Guanine nucleotide-binding protein beta subunit 2| Length = 346 Score = 65.9 bits (159), Expect = 9e-11 Identities = 41/139 (29%), Positives = 65/139 (46%), Gaps = 3/139 (2%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 LITG D K+ W + K + +G + LS G+ T K+WD+ E Sbjct: 163 LITGSGDMKICHWDLEKGVKTMDFNGHAGDIAGLSLSPDMKTYITGSVDKTAKLWDVREE 222 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTY---QGHTGRIDV 539 + F GH + +S+ HP G FAS S D +++D+R + I Y Q +TG Sbjct: 223 GHKQMFFGHDMDVSSVCYHPSGFGFASCSEDQTARMYDLRADQQIAQYEPPQKNTG-FTS 281 Query: 540 LRFTPDGRWIVSGGADSSV 596 + GR+++ GG + +V Sbjct: 282 CALSTSGRYLMCGGIEGNV 300 Score = 48.9 bits (115), Expect = 1e-05 Identities = 38/143 (26%), Positives = 60/143 (41%), Gaps = 9/143 (6%) Frame = +3 Query: 198 GGEDQKVNLWAVGKPTA------VLSLSGLTSPVESLSF-DSSEVMIGAGAASGTIKI-- 350 GG D + ++ V A V L G + S F D ++ G SG +KI Sbjct: 119 GGMDNQCTVYDVNNRDASGVAKMVKELMGYEGFLSSCRFLDDGHLITG----SGDMKICH 174 Query: 351 WDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGR 530 WD+E+ F GH + A L P + +GS D K+WD+R++ + GH Sbjct: 175 WDLEKGVKTMDFNGHAGDIAGLSLSPDMKTYITGSVDKTAKLWDVREEGHKQMFFGHDMD 234 Query: 531 IDVLRFTPDGRWIVSGGADSSVK 599 + + + P G S D + + Sbjct: 235 VSSVCYHPSGFGFASCSEDQTAR 257 Score = 40.0 bits (92), Expect = 0.005 Identities = 27/114 (23%), Positives = 44/114 (38%), Gaps = 6/114 (5%) Frame = +3 Query: 258 LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGD 437 L G + V S+ F G+ G + IWD A V+ + ++ P G+ Sbjct: 55 LKGHINKVNSVHFAGDSRHCVTGSLDGKLIIWDTWTANKVQIIPLRSAWVMTVAFSPSGN 114 Query: 438 FFASGSSDTNMKIWDMRKK------RCIHTYQGHTGRIDVLRFTPDGRWIVSGG 581 F A G D ++D+ + + + G+ G + RF DG I G Sbjct: 115 FVACGGMDNQCTVYDVNNRDASGVAKMVKELMGYEGFLSSCRFLDDGHLITGSG 168 Score = 32.7 bits (73), Expect = 0.82 Identities = 16/65 (24%), Positives = 28/65 (43%) Frame = +3 Query: 285 SLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDT 464 S + +S + G G + WD + + T +GH + + P G AS S D Sbjct: 281 SCALSTSGRYLMCGGIEGNVHSWDTMKQRHTGTLSGHENRITCISLCPNGMCLASTSWDQ 340 Query: 465 NMKIW 479 +++W Sbjct: 341 QVRLW 345
>GBB_CRYPA (O14435) Guanine nucleotide-binding protein beta subunit| Length = 359 Score = 65.9 bits (159), Expect = 9e-11 Identities = 36/131 (27%), Positives = 64/131 (48%), Gaps = 1/131 (0%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD- 299 +E HA ++C +F R+++T D W + T + + V S+S + Sbjct: 154 RELSGHAGYLSCCRF--INDRSILTSSGDMTCMKWDIETGTKQIEFADHLGDVMSISLNP 211 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 +++ +GA K+WDI K V+TF GH S+ ++ P G F +GS D +++ Sbjct: 212 TNQNTFISGACDAFAKLWDIRAGKAVQTFAGHESDINAIQFFPDGHSFVTGSDDATCRLF 271 Query: 480 DMRKKRCIHTY 512 D+R R ++ Y Sbjct: 272 DIRADRELNVY 282 Score = 60.5 bits (145), Expect = 4e-09 Identities = 38/160 (23%), Positives = 65/160 (40%), Gaps = 2/160 (1%) Frame = +3 Query: 126 EFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSS 305 EF H DV T I+G D LW + AV + +G S + ++ F Sbjct: 196 EFADHLGDVMSISLNPTNQNTFISGACDAFAKLWDIRAGKAVQTFAGHESDINAIQFFPD 255 Query: 306 EVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCA--SLDSHPFGDFFASGSSDTNMKIW 479 G+ T +++DI + + + C S+ + G +G D K+W Sbjct: 256 GHSFVTGSDDATCRLFDIRADRELNVYGSESILCGITSVATSVSGRLLFAGYDDFECKVW 315 Query: 480 DMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 D+ + + + GH R+ L + DG + +G DS +K Sbjct: 316 DVTRGEKVGSLVGHENRVSCLGVSNDGISLCTGSWDSLLK 355 Score = 57.4 bits (137), Expect = 3e-08 Identities = 38/140 (27%), Positives = 66/140 (47%), Gaps = 6/140 (4%) Frame = +3 Query: 198 GGEDQKVNLWAVGK----PTAVL-SLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIE 362 GG D +++ + + PT V LSG + F + ++ + +K WDIE Sbjct: 131 GGLDNICSIYNLNQNRDGPTRVARELSGHAGYLSCCRFINDRSILTSSGDMTCMK-WDIE 189 Query: 363 EAKVVRTFTGHRSNCASLDSHPFG-DFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDV 539 F H + S+ +P + F SG+ D K+WD+R + + T+ GH I+ Sbjct: 190 TGTKQIEFADHLGDVMSISLNPTNQNTFISGACDAFAKLWDIRAGKAVQTFAGHESDINA 249 Query: 540 LRFTPDGRWIVSGGADSSVK 599 ++F PDG V+G D++ + Sbjct: 250 IQFFPDGHSFVTGSDDATCR 269 Score = 45.8 bits (107), Expect = 9e-05 Identities = 29/122 (23%), Positives = 53/122 (43%), Gaps = 2/122 (1%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAV--GKPTAVLSLSGLTSPVESLS 293 +Q F H SD+ +F + +TG +D L+ + + V + + S++ Sbjct: 237 VQTFAGHESDINAIQFFP-DGHSFVTGSDDATCRLFDIRADRELNVYGSESILCGITSVA 295 Query: 294 FDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMK 473 S ++ AG K+WD+ + V + GH + + L G +GS D+ +K Sbjct: 296 TSVSGRLLFAGYDDFECKVWDVTRGEKVGSLVGHENRVSCLGVSNDGISLCTGSWDSLLK 355 Query: 474 IW 479 IW Sbjct: 356 IW 357 Score = 33.1 bits (74), Expect = 0.63 Identities = 17/74 (22%), Positives = 28/74 (37%) Frame = +3 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 K RT GH + ++ S S D + IWD +H + + + Sbjct: 62 KTKRTLKGHLAKIYAMHWSTDRRHLVSASQDGKLIIWDAYTTNKVHAIPLRSSWVMTCAY 121 Query: 549 TPDGRWIVSGGADS 590 P G ++ GG D+ Sbjct: 122 APSGNYVACGGLDN 135
>TBL1Y_HUMAN (Q9BQ87) F-box-like/WD-repeat protein TBL1Y (Transducin beta-like| 1Y protein) (Transducin-beta-like 1, Y-linked) Length = 522 Score = 65.9 bits (159), Expect = 9e-11 Identities = 38/170 (22%), Positives = 80/170 (47%), Gaps = 9/170 (5%) Frame = +3 Query: 114 YKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLS 293 + ++ F H ++V K+ + L + +D + +W++ + V L + + ++ Sbjct: 350 HPVKTFQGHTNEVNAIKWDP-SGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIK 408 Query: 294 FD---------SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFA 446 + +S +M+ + + T+++WD+E+ T H+ S+ P G + A Sbjct: 409 WSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLA 468 Query: 447 SGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 SGS D + IW+ + +H+YQG TG I + + G + + +D SV Sbjct: 469 SGSFDKYVHIWNTQSGSLVHSYQG-TGGIFEVCWNARGDKVGASASDGSV 517 Score = 65.1 bits (157), Expect = 1e-10 Identities = 38/167 (22%), Positives = 77/167 (46%), Gaps = 9/167 (5%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 Q+F H++ + + + T + D +++ +G V + G T+ V ++ +D Sbjct: 312 QQFPFHSAPALDVDW--QNNMTFASCSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDP 369 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGD---------FFASGS 455 S +++ + + T+KIW +++ V H ++ P G AS S Sbjct: 370 SGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASAS 429 Query: 456 SDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 D+ +++WD+ + C HT H + + F+PDG+++ SG D V Sbjct: 430 FDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYV 476 Score = 40.8 bits (94), Expect = 0.003 Identities = 30/137 (21%), Positives = 56/137 (40%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L G D +W A +L P+ +L ++ + + T IWD Sbjct: 250 LAMGSYDGFARIWTENGNLAS-TLGQHKGPIFALKWNKKGNYVLSAGVDKTTIIWDAHTG 308 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 + + F H + +D FAS S+D + + + + T+QGHT ++ +++ Sbjct: 309 EAKQQFPFHSAPALDVDWQN-NMTFASCSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIKW 367 Query: 549 TPDGRWIVSGGADSSVK 599 P G + S D ++K Sbjct: 368 DPSGMLLASCSDDMTLK 384 Score = 37.7 bits (86), Expect = 0.026 Identities = 33/132 (25%), Positives = 53/132 (40%), Gaps = 14/132 (10%) Frame = +3 Query: 240 PTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAK-------VVRTFT--- 389 P L G S V +++ ++ +G+ T +IW++ E V+R Sbjct: 169 PNKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREG 228 Query: 390 GH----RSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPD 557 GH + SLD + G A GS D +IW T H G I L++ Sbjct: 229 GHDVPSNKDVTSLDWNSDGTLLAMGSYDGFARIW-TENGNLASTLGQHKGPIFALKWNKK 287 Query: 558 GRWIVSGGADSS 593 G +++S G D + Sbjct: 288 GNYVLSAGVDKT 299
>COPB2_RAT (O35142) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| (p102) Length = 904 Score = 65.9 bits (159), Expect = 9e-11 Identities = 43/165 (26%), Positives = 74/165 (44%), Gaps = 4/165 (2%) Frame = +3 Query: 117 KLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSL-SGLTSPVESLS 293 ++ F AH+ + C T ++T +D + LW K + + G T V + Sbjct: 90 RVHMFEAHSDYIRCIAVHP-TQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIV 148 Query: 294 FDSSEVMIGAGAA-SGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGD--FFASGSSDT 464 + + A A+ TIK+W + + T GH +D + GD + SG+ D Sbjct: 149 INPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDR 208 Query: 465 NMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 +KIWD + K C+ T +GH + F P+ I++G D +V+ Sbjct: 209 LVKIWDYQNKTCVQTPEGHAQNVSCATFHPELPIIITGSEDGTVR 253 Score = 49.3 bits (116), Expect = 8e-06 Identities = 29/121 (23%), Positives = 50/121 (41%), Gaps = 2/121 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 Q F H V + + + D+ + +W +G + +L G V + + S Sbjct: 135 QVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYS 194 Query: 303 S--EVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 + + +GA +KIWD + V+T GH N + HP +GS D ++I Sbjct: 195 GGDKPYLISGADDRLVKIWDYQNKTCVQTPEGHAQNVSCATFHPELPIIITGSEDGTVRI 254 Query: 477 W 479 W Sbjct: 255 W 255 Score = 48.5 bits (114), Expect = 1e-05 Identities = 32/130 (24%), Positives = 53/130 (40%), Gaps = 2/130 (1%) Frame = +3 Query: 216 VNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGH 395 V +W T V + PV + F + + + GA I++++ + V F H Sbjct: 38 VCVWNHETQTLVKTFEVCDLPVRAAKFVARKNWVVTGADDMQIRVFNYNTLERVHMFEAH 97 Query: 396 RSNCASLDSHPFGDFFASGSSDTNMKIWDMRKK-RCIHTYQGHTGRIDVLRFTP-DGRWI 569 + HP F + S D +K+WD KK C ++GHT + + P D Sbjct: 98 SDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQF 157 Query: 570 VSGGADSSVK 599 S D ++K Sbjct: 158 ASASLDRTIK 167 Score = 29.6 bits (65), Expect = 6.9 Identities = 13/76 (17%), Positives = 32/76 (42%) Frame = +3 Query: 372 VVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFT 551 + R T S+D HP + + + ++ +W+ + + T++ + +F Sbjct: 6 IKRKLTAMSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFV 65 Query: 552 PDGRWIVSGGADSSVK 599 W+V+G D ++ Sbjct: 66 ARKNWVVTGADDMQIR 81
>YZLL_CAEEL (Q93847) Hypothetical WD-repeat protein K04G11.4| Length = 395 Score = 65.5 bits (158), Expect = 1e-10 Identities = 37/141 (26%), Positives = 73/141 (51%), Gaps = 1/141 (0%) Frame = +3 Query: 180 SRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDI 359 S+ +++ +D+ V ++ V V +L G T+ V F+ S +I +G+ TI+IW Sbjct: 160 SKLIVSCSDDKLVKVFDVSSGRCVKTLKGHTNYVFCCCFNPSGTLIASGSFDETIRIWCA 219 Query: 360 EEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHT-YQGHTGRID 536 + + GH +S+ + G + ASGS D ++IWD C+ T I Sbjct: 220 RNGNTIFSIPGHEDPVSSVCFNRDGAYLASGSYDGIVRIWDSTTGTCVKTLIDEEHPPIT 279 Query: 537 VLRFTPDGRWIVSGGADSSVK 599 ++F+P+G++I++ ++++K Sbjct: 280 HVKFSPNGKYILASNLNNTLK 300 Score = 63.2 bits (152), Expect = 6e-10 Identities = 44/173 (25%), Positives = 74/173 (42%), Gaps = 2/173 (1%) Frame = +3 Query: 87 PSRMATKRAYKLQEFV--AHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSL 260 PS YKL + AH ++ KF R + +G D + +W + +L Sbjct: 87 PSAANLWPTYKLVAEIPNAHKKSISGIKFSP-DGRYMGSGSADCSIKIWRMDF-VYEKTL 144 Query: 261 SGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDF 440 G + S+ S +I + + +K++D+ + V+T GH + +P G Sbjct: 145 MGHRLGINEFSWSSDSKLIVSCSDDKLVKVFDVSSGRCVKTLKGHTNYVFCCCFNPSGTL 204 Query: 441 FASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 ASGS D ++IW R I + GH + + F DG ++ SG D V+ Sbjct: 205 IASGSFDETIRIWCARNGNTIFSIPGHEDPVSSVCFNRDGAYLASGSYDGIVR 257 Score = 55.5 bits (132), Expect = 1e-07 Identities = 39/158 (24%), Positives = 70/158 (44%), Gaps = 4/158 (2%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSP-VESLSFDSSEVM 314 H V+ F R L +G D V +W T V +L P + + F + Sbjct: 231 HEDPVSSVCFN-RDGAYLASGSYDGIVRIWDSTTGTCVKTLIDEEHPPITHVKFSPNGKY 289 Query: 315 IGAGAASGTIKIWDIEEAKVVRTFTGHRSN--CASLD-SHPFGDFFASGSSDTNMKIWDM 485 I A + T+K+WD ++ +V++ +TGH ++ C + + S G + SGS D + IW++ Sbjct: 290 ILASNLNNTLKLWDYQKLRVLKEYTGHENSKYCVAANFSVTGGKWIVSGSEDHKVYIWNL 349 Query: 486 RKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 + + + T GH + P I S + ++ Sbjct: 350 QTREILQTLDGHNTAVMCTDCHPGQNIIASAALEPDMR 387 Score = 35.4 bits (80), Expect = 0.13 Identities = 16/57 (28%), Positives = 30/57 (52%), Gaps = 2/57 (3%) Frame = +3 Query: 315 IGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGS--SDTNMKIW 479 I +G+ + IW+++ ++++T GH + D HP + AS + D +KIW Sbjct: 335 IVSGSEDHKVYIWNLQTREILQTLDGHNTAVMCTDCHPGQNIIASAALEPDMRIKIW 391
>GBB_LOLFO (P23232) Guanine nucleotide-binding protein beta subunit| Length = 341 Score = 65.5 bits (158), Expect = 1e-10 Identities = 42/157 (26%), Positives = 72/157 (45%), Gaps = 2/157 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 +E H ++C +F ++T D LW + + S G T V SLS Sbjct: 138 RELPGHTGYLSCCRF--IDDNQIVTSSGDMTCALWNIETGNQITSFGGHTGDVMSLSLAP 195 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 +GA + K++DI + +TFTGH S+ ++ P G FA+GS D +++D Sbjct: 196 DMRTFVSGACDASAKLFDIRDGICKQTFTGHESDINAITYFPNGFAFATGSDDATCRLFD 255 Query: 483 MRKKRCI--HTYQGHTGRIDVLRFTPDGRWIVSGGAD 587 +R + I +++ I + F+ GR ++ G D Sbjct: 256 IRADQEIGMYSHDNIICGITSVAFSKSGRLLLGGYDD 292 Score = 57.4 bits (137), Expect = 3e-08 Identities = 36/139 (25%), Positives = 66/139 (47%), Gaps = 5/139 (3%) Frame = +3 Query: 198 GGEDQKVNLWAV----GKPTAVLSLSGLTSPVESLSF-DSSEVMIGAGAASGTIKIWDIE 362 GG D +++++ G L G T + F D ++++ +G T +W+IE Sbjct: 116 GGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFIDDNQIVTSSGDM--TCALWNIE 173 Query: 363 EAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVL 542 + +F GH + SL P F SG+ D + K++D+R C T+ GH I+ + Sbjct: 174 TGNQITSFGGHTGDVMSLSLAPDMRTFVSGACDASAKLFDIRDGICKQTFTGHESDINAI 233 Query: 543 RFTPDGRWIVSGGADSSVK 599 + P+G +G D++ + Sbjct: 234 TYFPNGFAFATGSDDATCR 252 Score = 39.3 bits (90), Expect = 0.009 Identities = 27/122 (22%), Positives = 50/122 (40%), Gaps = 2/122 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAV--GKPTAVLSLSGLTSPVESLSF 296 Q F H SD+ + TG +D L+ + + + S + + S++F Sbjct: 221 QTFTGHESDINAITYFPN-GFAFATGSDDATCRLFDIRADQEIGMYSHDNIICGITSVAF 279 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 S ++ G +WD+ + + GH + + L G A+GS D+ +KI Sbjct: 280 SKSGRLLLGGYDDFNCNVWDVLKQERAGVLAGHDNRVSCLGVTEDGMAVATGSWDSFLKI 339 Query: 477 WD 482 W+ Sbjct: 340 WN 341 Score = 30.4 bits (67), Expect = 4.1 Identities = 15/71 (21%), Positives = 27/71 (38%) Frame = +3 Query: 378 RTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPD 557 RT GH + ++ S S D + +WD +H + + + P Sbjct: 50 RTLRGHLAKIYAMHWASDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAYAPS 109 Query: 558 GRWIVSGGADS 590 G ++ GG D+ Sbjct: 110 GNYVACGGLDN 120
>UTP13_YEAST (Q05946) U3 small nucleolar RNA-associated protein 13 (U3| snoRNA-associated protein 13) Length = 817 Score = 65.1 bits (157), Expect = 1e-10 Identities = 39/172 (22%), Positives = 74/172 (43%), Gaps = 14/172 (8%) Frame = +3 Query: 126 EFVAHASDVTCAKFGKRTSRT----LITGGEDQKVNLWAVGKPTA-----VLSLSGLT-- 272 +++ H++ VT S+ L+T D + W + KPTA ++ +S T Sbjct: 429 KYIGHSAAVTAVGLPNIVSKGYPEFLLTASNDLTIKKWIIPKPTASMDVQIIKVSEYTRH 488 Query: 273 ---SPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFF 443 + +LS ++ + + T KIW++E ++ T H+ + + Sbjct: 489 AHEKDINALSVSPNDSIFATASYDKTCKIWNLENGELEATLANHKRGLWDVSFCQYDKLL 548 Query: 444 ASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 A+ S D +KIW + + T +GHT + F + ++S GAD +K Sbjct: 549 ATSSGDKTVKIWSLDTFSVMKTLEGHTNAVQRCSFINKQKQLISCGADGLIK 600 Score = 61.2 bits (147), Expect = 2e-09 Identities = 36/121 (29%), Positives = 62/121 (51%), Gaps = 11/121 (9%) Frame = +3 Query: 267 LTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGD--- 437 ++SP L DS+ ++ G G+I + DIE + +F GH +SL + + Sbjct: 101 ISSPSYILDADSTSTLLAVGGTDGSIIVVDIENGYITHSFKGHGGTISSLKFYGQLNSKI 160 Query: 438 -FFASGSSDTNMKIWDMRKKRCIHTYQGHTGRI---DVLRFTPDGRW----IVSGGADSS 593 ASG ++ +K+WD+ K++C+HT Q HT + D++ PD ++SGG D Sbjct: 161 WLLASGDTNGMVKVWDLVKRKCLHTLQEHTSAVRGLDIIE-VPDNDEPSLNLLSGGRDDI 219 Query: 594 V 596 + Sbjct: 220 I 220 Score = 59.3 bits (142), Expect = 8e-09 Identities = 41/172 (23%), Positives = 70/172 (40%), Gaps = 5/172 (2%) Frame = +3 Query: 87 PSRMATKRAYKLQEFVAHA--SDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSL 260 P+ + K+ E+ HA D+ S T D+ +W + +L Sbjct: 471 PTASMDVQIIKVSEYTRHAHEKDINALSVSPNDS-IFATASYDKTCKIWNLENGELEATL 529 Query: 261 SGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRS---NCASLDSHPF 431 + + +SF + ++ + T+KIW ++ V++T GH + C+ ++ Sbjct: 530 ANHKRGLWDVSFCQYDKLLATSSGDKTVKIWSLDTFSVMKTLEGHTNAVQRCSFINKQKQ 589 Query: 432 GDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGAD 587 S +D +KIWD C+ T GH R+ L DG IVS AD Sbjct: 590 ---LISCGADGLIKIWDCSSGECLKTLDGHNNRLWALSTMNDGDMIVSADAD 638 Score = 55.5 bits (132), Expect = 1e-07 Identities = 27/99 (27%), Positives = 49/99 (49%) Frame = +3 Query: 183 RTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIE 362 + L T D+ V +W++ + + +L G T+ V+ SF + + + + A G IKIWD Sbjct: 546 KLLATSSGDKTVKIWSLDTFSVMKTLEGHTNAVQRCSFINKQKQLISCGADGLIKIWDCS 605 Query: 363 EAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 + ++T GH + +L + GD S +D + W Sbjct: 606 SGECLKTLDGHNNRLWALSTMNDGDMIVSADADGVFQFW 644
>WDR48_CHICK (Q5F3K4) WD-repeat protein 48| Length = 678 Score = 65.1 bits (157), Expect = 1e-10 Identities = 39/143 (27%), Positives = 67/143 (46%), Gaps = 9/143 (6%) Frame = +3 Query: 195 TGGEDQKVNLWAVGKPTAVL---------SLSGLTSPVESLSFDSSEVMIGAGAASGTIK 347 + G D+++ LW V TA+ SLSG + SL+ + +I +G+ ++ Sbjct: 134 SAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQMGTVIVSGSTEKVLR 193 Query: 348 IWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTG 527 +WD + GH N +L + G SGSSD +++W + ++RCI TY+ H Sbjct: 194 VWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDE 253 Query: 528 RIDVLRFTPDGRWIVSGGADSSV 596 + L+ + SGG D + Sbjct: 254 GVWALQVNEAFTHVYSGGRDRKI 276 Score = 58.9 bits (141), Expect = 1e-08 Identities = 32/148 (21%), Positives = 67/148 (45%), Gaps = 9/148 (6%) Frame = +3 Query: 183 RTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIE 362 +TLI+ D V +W K + +L V++L++ + ++ + I +WD+ Sbjct: 88 KTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVN 147 Query: 363 EAKVVR---------TFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQ 515 + + +G++ + SL + G SGS++ +++WD R + + Sbjct: 148 TLTALTASNNTVTTSSLSGNKDSIYSLAMNQMGTVIVSGSTEKVLRVWDPRTCAKLMKLK 207 Query: 516 GHTGRIDVLRFTPDGRWIVSGGADSSVK 599 GHT + L DG +SG +D +++ Sbjct: 208 GHTDNVKALLLNRDGTQCLSGSSDGTIR 235 Score = 42.0 bits (97), Expect = 0.001 Identities = 25/109 (22%), Positives = 43/109 (39%), Gaps = 3/109 (2%) Frame = +3 Query: 279 VESLSFDSSEVMIGAGAASGTIKIWDIEEAK---VVRTFTGHRSNCASLDSHPFGDFFAS 449 V +L D + + I+IW + + K + + H + G S Sbjct: 33 VNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDIVLCCNGKTLIS 92 Query: 450 GSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 SSDT +K+W+ K C+ T + H + L + D + S G D + Sbjct: 93 ASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQI 141 Score = 40.8 bits (94), Expect = 0.003 Identities = 24/102 (23%), Positives = 46/102 (45%), Gaps = 1/102 (0%) Frame = +3 Query: 186 TLITGGEDQKV-NLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIE 362 T+I G +KV +W ++ L G T V++L + +G++ GTI++W + Sbjct: 181 TVIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLG 240 Query: 363 EAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMR 488 + + + T+ H +L + SG D + D+R Sbjct: 241 QQRCIATYRVHDEGVWALQVNEAFTHVYSGGRDRKIYCTDLR 282
>TLE1_XENLA (O42469) Enhancer of split groucho-like protein 1| Length = 767 Score = 65.1 bits (157), Expect = 1e-10 Identities = 35/141 (24%), Positives = 66/141 (46%), Gaps = 2/141 (1%) Frame = +3 Query: 183 RTLITGGEDQKVNLWAVGKPTAVLS--LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWD 356 R+LI GGE +++W + PT + L+ +L+ + + + G I +WD Sbjct: 540 RSLIVGGEASTLSIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIVVWD 599 Query: 357 IEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRID 536 ++ +VR F GH + +D G +G D ++ WD+R+ R + + +I Sbjct: 600 LQNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRCWDLREGRQLQQHD-FNSQIF 658 Query: 537 VLRFTPDGRWIVSGGADSSVK 599 L + P G W+ G S+++ Sbjct: 659 SLGYCPTGEWLAVGMESSNIE 679 Score = 61.2 bits (147), Expect = 2e-09 Identities = 44/166 (26%), Positives = 74/166 (44%), Gaps = 7/166 (4%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKP---TAVLSLSGLTSP--VES 287 Q V + +V CA ++R + TGG+ V +W VG+P T V L L + S Sbjct: 474 QLHVLNHGEVVCAVTISNSTRHVYTGGKGC-VKVWDVGQPGTKTPVAQLDCLNRDNYIRS 532 Query: 288 LSFDSSEVMIGAGAASGTIKIWDIEEA--KVVRTFTGHRSNCASLDSHPFGDFFASGSSD 461 + G + T+ IWD+ ++ T C +L P S SD Sbjct: 533 CKLLPDGRSLIVGGEASTLSIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSD 592 Query: 462 TNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 N+ +WD++ + + +QGHT + + DG + +GG D++V+ Sbjct: 593 GNIVVWDLQNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVR 638
>PWP2_MOUSE (Q8BU03) Periodic tryptophan protein 2 homolog| Length = 919 Score = 65.1 bits (157), Expect = 1e-10 Identities = 38/141 (26%), Positives = 73/141 (51%), Gaps = 4/141 (2%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 ++TGG+D KV +W ++L+ +S V ++F ++ +I + GT++ +D+ Sbjct: 388 IVTGGDDGKVKVWNTLSGFCFVTLTEHSSGVTGVTFTTTGHVIVTSSLDGTVRAFDLHRY 447 Query: 369 KVVRTFTGHRS---NCASLDSHPFGDFFASGSSDT-NMKIWDMRKKRCIHTYQGHTGRID 536 + RTFT R +C ++DS G+ ++G+ D+ + +W M+ R + GH G + Sbjct: 448 RNFRTFTSPRPTQFSCVAVDSS--GEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPVS 505 Query: 537 VLRFTPDGRWIVSGGADSSVK 599 L F P + S D +V+ Sbjct: 506 GLCFNPMKSILASASWDKTVR 526 Score = 57.4 bits (137), Expect = 3e-08 Identities = 39/153 (25%), Positives = 71/153 (46%), Gaps = 1/153 (0%) Frame = +3 Query: 144 SDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGA 323 +++T A + K+T L+TG +L + + + SLS V S++ +SS I Sbjct: 289 NNLTSAAYHKKT-HLLVTGFASGIFHLHELPEFNLIHSLSISDQRVASVAINSSGDWIAF 347 Query: 324 GAAS-GTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRC 500 G + G + +W+ + V GH ++ +L P G + +G D +K+W+ C Sbjct: 348 GCSGMGQLLVWEWQSESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFC 407 Query: 501 IHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 T H+ + + FT G IV+ D +V+ Sbjct: 408 FVTLTEHSSGVTGVTFTTTGHVIVTSSLDGTVR 440 Score = 53.5 bits (127), Expect = 4e-07 Identities = 30/117 (25%), Positives = 59/117 (50%), Gaps = 1/117 (0%) Frame = +3 Query: 252 LSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPF 431 L+ G + + S ++ ++ G ASG + ++ E ++ + + AS+ + Sbjct: 282 LNKEGDFNNLTSAAYHKKTHLLVTGFASGIFHLHELPEFNLIHSLSISDQRVASVAINSS 341 Query: 432 GDFFASGSSDT-NMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 GD+ A G S + +W+ + + + QGH + L ++PDG++IV+GG D VK Sbjct: 342 GDWIAFGCSGMGQLLVWEWQSESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVK 398 Score = 43.9 bits (102), Expect = 4e-04 Identities = 38/158 (24%), Positives = 65/158 (41%), Gaps = 5/158 (3%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSP----VESLSFDSS 305 H+S VT F T ++T D V + + + + TSP ++ DSS Sbjct: 414 HSSGVTGVTF-TTTGHVIVTSSLDGTVRAFDLHR---YRNFRTFTSPRPTQFSCVAVDSS 469 Query: 306 EVMIGAGAA-SGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 ++ AGA S I +W ++ +++ +GH + L +P AS S D +++WD Sbjct: 470 GEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPVSGLCFNPMKSILASASWDKTVRLWD 529 Query: 483 MRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 M T + F PDG + +S + Sbjct: 530 MFDSWRTKETLTLTSDALAVTFRPDGAELAVATLNSQI 567 Score = 37.0 bits (84), Expect = 0.044 Identities = 30/154 (19%), Positives = 67/154 (43%), Gaps = 21/154 (13%) Frame = +3 Query: 198 GGEDQ-KVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKV 374 G +D ++ +W++ + LSG PV L F+ + ++ + + T+++WD+ ++ Sbjct: 476 GAQDSFEIFVWSMQTGRLLDVLSGHEGPVSGLCFNPMKSILASASWDKTVRLWDMFDSWR 535 Query: 375 VRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGH----TGRIDV- 539 + S+ ++ P G A + ++ + WD + + +G TGR ++ Sbjct: 536 TKETLTLTSDALAVTFRPDGAELAVATLNSQITFWDPENAVQVGSIEGRHDLKTGRKELD 595 Query: 540 ---------------LRFTPDGRWIVSGGADSSV 596 L ++ DG+ I++GG V Sbjct: 596 KITAKHSAKGKAFTTLCYSADGQSILAGGMSKFV 629
>TB1RA_XENLA (Q7SZM9) F-box-like/WD-repeat-containing protein TBL1XR1-A| (Transducin beta-like 1X-related protein 1-A) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1-A) (TBL1-related protein 1-A) (xTBLR1) Length = 519 Score = 65.1 bits (157), Expect = 1e-10 Identities = 38/168 (22%), Positives = 79/168 (47%), Gaps = 9/168 (5%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 ++ F H ++V K+ T L + +D + +W++ T V L + ++ + Sbjct: 347 IKTFQGHTNEVNAIKWDP-TGNLLASCSDDMTLKIWSMKHDTCVHDLQAHNKEIYTIKWS 405 Query: 300 ---------SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASG 452 ++ +M+ + + T+++WD++ + T T H+ S+ P G + ASG Sbjct: 406 PTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASG 465 Query: 453 SSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 S D + IW+ + +H+Y+G TG I + + G + + +D SV Sbjct: 466 SFDKCVHIWNTQTGALVHSYRG-TGGIFEVCWNAAGDKVGASASDGSV 512 Score = 58.9 bits (141), Expect = 1e-08 Identities = 34/157 (21%), Positives = 67/157 (42%) Frame = +3 Query: 90 SRMATKRAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGL 269 +R+ TK H + K+ K+ +++ G D+ +W A Sbjct: 254 ARIWTKDGNLASTLGQHKGPIFALKWNKK-GNFILSAGVDKTTIIWDAHTGEAKQQFPFH 312 Query: 270 TSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFAS 449 ++P + + S+ + I + + + + ++TF GH + ++ P G+ AS Sbjct: 313 SAPALDVDWQSNNTFASC-STDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLAS 371 Query: 450 GSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDG 560 S D +KIW M+ C+H Q H I ++++P G Sbjct: 372 CSDDMTLKIWSMKHDTCVHDLQAHNKEIYTIKWSPTG 408 Score = 49.7 bits (117), Expect = 6e-06 Identities = 34/137 (24%), Positives = 60/137 (43%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L TG D +W A +L P+ +L ++ I + T IWD Sbjct: 245 LATGSYDGFARIWTKDGNLAS-TLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTG 303 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 + + F H + +D + FAS S+D + + + + R I T+QGHT ++ +++ Sbjct: 304 EAKQQFPFHSAPALDVDWQS-NNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKW 362 Query: 549 TPDGRWIVSGGADSSVK 599 P G + S D ++K Sbjct: 363 DPTGNLLASCSDDMTLK 379 Score = 36.6 bits (83), Expect = 0.057 Identities = 30/126 (23%), Positives = 51/126 (40%), Gaps = 14/126 (11%) Frame = +3 Query: 258 LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNC---------- 407 L G S V +++ ++ +G+ T +IW++ E + +C Sbjct: 170 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPS 229 Query: 408 ----ASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVS 575 SLD + G A+GS D +IW + T H G I L++ G +I+S Sbjct: 230 NKDVTSLDWNSEGTLLATGSYDGFARIW-TKDGNLASTLGQHKGPIFALKWNKKGNFILS 288 Query: 576 GGADSS 593 G D + Sbjct: 289 AGVDKT 294 Score = 30.0 bits (66), Expect = 5.3 Identities = 15/44 (34%), Positives = 22/44 (50%) Frame = +3 Query: 354 DIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDM 485 +I +K V GH S +P D ASGS D+ +IW++ Sbjct: 161 EIPSSKAV-VLRGHESEVFICAWNPVSDLLASGSGDSTARIWNL 203
>PRP46_DEBHA (Q6BU94) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 417 Score = 65.1 bits (157), Expect = 1e-10 Identities = 36/160 (22%), Positives = 69/160 (43%), Gaps = 5/160 (3%) Frame = +3 Query: 135 AHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVM 314 AH V T++ +TG D + +W + +++G V SL+ S Sbjct: 119 AHQGWVRSCTVDPVTNKWFVTGSSDSTIKIWDLASLNLKATITGHIMGVRSLAVSSRYPY 178 Query: 315 IGAGAASGTIKIWDIEEAK-----VVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 + +G+ T+K WD+E +R + GH ++ HP D +G D+ +++W Sbjct: 179 LFSGSEDKTVKCWDLERTNSLLGCQIRNYHGHVGGIYAMALHPELDLLFTGGRDSVIRVW 238 Query: 480 DMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 D+R + I GH I + I++ D++++ Sbjct: 239 DLRSRTEIMVLSGHRSDITSIASQIGDPQIITSSMDATIR 278 Score = 63.2 bits (152), Expect = 6e-10 Identities = 37/140 (26%), Positives = 63/140 (45%), Gaps = 3/140 (2%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L TGG D + +W + T ++ LSG S + S++ + I + TI++WDI +A Sbjct: 226 LFTGGRDSVIRVWDLRSRTEIMVLSGHRSDITSIASQIGDPQIITSSMDATIRLWDIRKA 285 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGR---IDV 539 T H + + HP SG + N+K W + ++ + GH+G I+ Sbjct: 286 TTQLALTHHSKSIRLMAMHPQEMTMCSGDTSGNLKEWLLPGGELLNEF-GHSGENKIINT 344 Query: 540 LRFTPDGRWIVSGGADSSVK 599 L P + SG D ++ Sbjct: 345 LSINPSNNTLFSGYDDGRME 364 Score = 54.3 bits (129), Expect = 3e-07 Identities = 30/142 (21%), Positives = 60/142 (42%), Gaps = 5/142 (3%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLS-----GLTSPVESLSFDSSEVMIGAGAASGTIKIW 353 L +G ED+ V W + + ++L G + +++ ++ G I++W Sbjct: 179 LFSGSEDKTVKCWDLERTNSLLGCQIRNYHGHVGGIYAMALHPELDLLFTGGRDSVIRVW 238 Query: 354 DIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRI 533 D+ + +GHRS+ S+ S + S D +++WD+RK H+ I Sbjct: 239 DLRSRTEIMVLSGHRSDITSIASQIGDPQIITSSMDATIRLWDIRKATTQLALTHHSKSI 298 Query: 534 DVLRFTPDGRWIVSGGADSSVK 599 ++ P + SG ++K Sbjct: 299 RLMAMHPQEMTMCSGDTSGNLK 320
>UTP15_PONPY (Q5REE0) U3 small nucleolar RNA-associated protein 15 homolog| Length = 518 Score = 65.1 bits (157), Expect = 1e-10 Identities = 44/146 (30%), Positives = 72/146 (49%), Gaps = 4/146 (2%) Frame = +3 Query: 156 CAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAAS 335 CA F ++ R ++ G ED V L+ + + G T V ++ F + + + +GA Sbjct: 85 CATF-RQDGRLIVAGSEDGGVQLFDISGRAPLRQFEGHTKAVHTVDFTADKYHVVSGADD 143 Query: 336 GTIKIWDIEEAKVVRTFTGH----RSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCI 503 T+K+WDI +K V TF H R CAS +P D F +GS D +K++D R + Sbjct: 144 YTVKLWDIPNSKEVLTFKEHSDYVRCGCAS-KLNP--DLFITGSYDHTVKMFDARTSESV 200 Query: 504 HTYQGHTGRIDVLRFTPDGRWIVSGG 581 + + H ++ + P G +VS G Sbjct: 201 LSVE-HGQPVESVLLFPSGGLLVSAG 225 Score = 43.9 bits (102), Expect = 4e-04 Identities = 24/93 (25%), Positives = 44/93 (47%) Frame = +3 Query: 321 AGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRC 500 A AS I I+ + ++TF+ + G +GS D ++++D+ + Sbjct: 55 AVTASSRIHIYGRYSQESIKTFSRFKDTAYCATFRQDGRLIVAGSEDGGVQLFDISGRAP 114 Query: 501 IHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 + ++GHT + + FT D +VSG D +VK Sbjct: 115 LRQFEGHTKAVHTVDFTADKYHVVSGADDYTVK 147 Score = 42.4 bits (98), Expect = 0.001 Identities = 27/132 (20%), Positives = 59/132 (44%), Gaps = 3/132 (2%) Frame = +3 Query: 213 KVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTG 392 +++++ ++ + S +F +I AG+ G ++++DI +R F G Sbjct: 61 RIHIYGRYSQESIKTFSRFKDTAYCATFRQDGRLIVAGSEDGGVQLFDISGRAPLRQFEG 120 Query: 393 HRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRID---VLRFTPDGR 563 H ++D SG+ D +K+WD+ + + T++ H+ + + PD Sbjct: 121 HTKAVHTVDFTADKYHVVSGADDYTVKLWDIPNSKEVLTFKEHSDYVRCGCASKLNPD-- 178 Query: 564 WIVSGGADSSVK 599 ++G D +VK Sbjct: 179 LFITGSYDHTVK 190 Score = 41.2 bits (95), Expect = 0.002 Identities = 33/130 (25%), Positives = 56/130 (43%), Gaps = 2/130 (1%) Frame = +3 Query: 129 FVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVES-LSFDSS 305 F H+ V C K ITG D V ++ +VLS+ PVES L F S Sbjct: 160 FKEHSDYVRCGCASKLNPDLFITGSYDHTVKMFDARTSESVLSVEH-GQPVESVLLFPSG 218 Query: 306 EVMIGAGAASGTIKIWD-IEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 +++ AG +K+ D ++ +++ + H L G SGS D +K++ Sbjct: 219 GLLVSAGGR--YVKVCDMLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYS 276 Query: 483 MRKKRCIHTY 512 + +H++ Sbjct: 277 TTSYKVVHSF 286
>TB1RB_XENLA (Q6GPC6) F-box-like/WD-repeat-containing protein TBL1XR1-B| (Transducin beta-like 1X-related homolog 1-B) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1-B) (TBL1-related protein 1-B) Length = 522 Score = 65.1 bits (157), Expect = 1e-10 Identities = 38/168 (22%), Positives = 79/168 (47%), Gaps = 9/168 (5%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 ++ F H ++V K+ T L + +D + +W++ T V L + ++ + Sbjct: 350 IKTFQGHTNEVNAIKWDP-TGNLLASCSDDMTLKIWSMKHDTCVHDLQAHNKEIYTIKWS 408 Query: 300 ---------SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASG 452 ++ +M+ + + T+++WD++ + T T H+ S+ P G + ASG Sbjct: 409 PTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASG 468 Query: 453 SSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 S D + IW+ + +H+Y+G TG I + + G + + +D SV Sbjct: 469 SFDKCVHIWNTQTGALVHSYRG-TGGIFEVCWNAAGDKVGASASDGSV 515 Score = 58.9 bits (141), Expect = 1e-08 Identities = 34/157 (21%), Positives = 67/157 (42%) Frame = +3 Query: 90 SRMATKRAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGL 269 +R+ TK H + K+ K+ +++ G D+ +W A Sbjct: 257 ARIWTKDGNLASTLGQHKGPIFALKWNKK-GNFILSAGVDKTTIIWDAHTGEAKQQFPFH 315 Query: 270 TSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFAS 449 ++P + + S+ + I + + + + ++TF GH + ++ P G+ AS Sbjct: 316 SAPALDVDWQSNNTFASC-STDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLAS 374 Query: 450 GSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDG 560 S D +KIW M+ C+H Q H I ++++P G Sbjct: 375 CSDDMTLKIWSMKHDTCVHDLQAHNKEIYTIKWSPTG 411 Score = 49.7 bits (117), Expect = 6e-06 Identities = 34/137 (24%), Positives = 60/137 (43%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L TG D +W A +L P+ +L ++ I + T IWD Sbjct: 248 LATGSYDGFARIWTKDGNLAS-TLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTG 306 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 + + F H + +D + FAS S+D + + + + R I T+QGHT ++ +++ Sbjct: 307 EAKQQFPFHSAPALDVDWQS-NNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKW 365 Query: 549 TPDGRWIVSGGADSSVK 599 P G + S D ++K Sbjct: 366 DPTGNLLASCSDDMTLK 382 Score = 38.9 bits (89), Expect = 0.011 Identities = 31/132 (23%), Positives = 54/132 (40%), Gaps = 14/132 (10%) Frame = +3 Query: 240 PTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNC---- 407 P+ + L G S V +++ ++ +G+ T +IW++ E + +C Sbjct: 167 PSKAVVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREG 226 Query: 408 ----------ASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPD 557 SLD + G A+GS D +IW + T H G I L++ Sbjct: 227 GQDVPSNKDVTSLDWNSEGTLLATGSYDGFARIW-TKDGNLASTLGQHKGPIFALKWNKK 285 Query: 558 GRWIVSGGADSS 593 G +I+S G D + Sbjct: 286 GNFILSAGVDKT 297 Score = 29.6 bits (65), Expect = 6.9 Identities = 15/44 (34%), Positives = 22/44 (50%) Frame = +3 Query: 354 DIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDM 485 +I +K V GH S +P D ASGS D+ +IW++ Sbjct: 164 EIPPSKAV-VLRGHESEVFICAWNPVSDLLASGSGDSTARIWNL 206
>PRP46_CANAL (Q5A7Q3) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 389 Score = 64.7 bits (156), Expect = 2e-10 Identities = 30/108 (27%), Positives = 56/108 (51%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L +GG+D V +W + ++L G T+ + S+ D ++ + + GTI++WD+ ++ Sbjct: 190 LFSGGKDCVVRVWDIRSRVEAMTLLGHTNDITSIETDYNDPQVITSSMDGTIRLWDLRKS 249 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTY 512 K T H + S+ SHP F SG S+ +K W + K ++ + Sbjct: 250 KTELLITNHSKSIRSMKSHPKEATFVSGDSNGEIKQWLLPKGELLNEF 297 Score = 62.8 bits (151), Expect = 7e-10 Identities = 34/160 (21%), Positives = 68/160 (42%), Gaps = 5/160 (3%) Frame = +3 Query: 135 AHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVM 314 AH + + T++ +TG D + +W + L+G + SL Sbjct: 83 AHQGWIRAIALDEITNKWYVTGSADSTIKIWDFENNSLKAVLTGHVLGIRSLCISKRHPY 142 Query: 315 IGAGAASGTIKIWDIEEAK-----VVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 + +G +++ WD+E + +R++ GH S+ HP D SG D +++W Sbjct: 143 LFSGGEDKSLRCWDLERSNSDAGCQIRSYHGHLGGVYSIGLHPELDVLFSGGKDCVVRVW 202 Query: 480 DMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 D+R + T GHT I + + +++ D +++ Sbjct: 203 DIRSRVEAMTLLGHTNDITSIETDYNDPQVITSSMDGTIR 242 Score = 54.3 bits (129), Expect = 3e-07 Identities = 31/142 (21%), Positives = 62/142 (43%), Gaps = 5/142 (3%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTA-----VLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIW 353 L +GGED+ + W + + + + S G V S+ ++ +G +++W Sbjct: 143 LFSGGEDKSLRCWDLERSNSDAGCQIRSYHGHLGGVYSIGLHPELDVLFSGGKDCVVRVW 202 Query: 354 DIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRI 533 DI T GH ++ S+++ + S D +++WD+RK + H+ I Sbjct: 203 DIRSRVEAMTLLGHTNDITSIETDYNDPQVITSSMDGTIRLWDLRKSKTELLITNHSKSI 262 Query: 534 DVLRFTPDGRWIVSGGADSSVK 599 ++ P VSG ++ +K Sbjct: 263 RSMKSHPKEATFVSGDSNGEIK 284 Score = 34.3 bits (77), Expect = 0.28 Identities = 23/82 (28%), Positives = 37/82 (45%), Gaps = 3/82 (3%) Frame = +3 Query: 363 EAKVVRTFTGHRSN---CASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRI 533 E K++RT G +LD ++ +GS+D+ +KIWD GH I Sbjct: 73 EWKLLRTLAGAHQGWIRAIALDEIT-NKWYVTGSADSTIKIWDFENNSLKAVLTGHVLGI 131 Query: 534 DVLRFTPDGRWIVSGGADSSVK 599 L + ++ SGG D S++ Sbjct: 132 RSLCISKRHPYLFSGGEDKSLR 153
>PRP19_CAEEL (Q10051) PRP19/PSO4 homolog| Length = 492 Score = 64.7 bits (156), Expect = 2e-10 Identities = 37/118 (31%), Positives = 59/118 (50%), Gaps = 2/118 (1%) Frame = +3 Query: 234 GKPTAVLSLS-GLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCA 410 GK +S+ G V S+ F ++ G GAA +KIWD++ V F GH + Sbjct: 325 GKSLCKVSVEPGSQIAVHSIEFHPDGLIFGTGAADAVVKIWDLKNQTVAAAFPGHTAAVR 384 Query: 411 SLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGR-IDVLRFTPDGRWIVSGG 581 S+ G + A+GS D +K+WD+RK + + T+ + I+ L F G ++ GG Sbjct: 385 SIAFSENGYYLATGSEDGEVKLWDLRKLKNLKTFANEEKQPINSLSFDMTGTFLGIGG 442 Score = 59.7 bits (143), Expect = 6e-09 Identities = 34/141 (24%), Positives = 65/141 (46%), Gaps = 3/141 (2%) Frame = +3 Query: 186 TLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEE 365 T I+ D + +W+ ++ + +PV +S ++S I + + DI Sbjct: 265 TAISASADSHIRVWSATDSSSKAIIDVHQAPVTDISLNASGDYILSASDDSYWAFSDIRS 324 Query: 366 AKV---VRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRID 536 K V G + S++ HP G F +G++D +KIWD++ + + GHT + Sbjct: 325 GKSLCKVSVEPGSQIAVHSIEFHPDGLIFGTGAADAVVKIWDLKNQTVAAAFPGHTAAVR 384 Query: 537 VLRFTPDGRWIVSGGADSSVK 599 + F+ +G ++ +G D VK Sbjct: 385 SIAFSENGYYLATGSEDGEVK 405 Score = 56.2 bits (134), Expect = 7e-08 Identities = 32/136 (23%), Positives = 63/136 (46%), Gaps = 1/136 (0%) Frame = +3 Query: 195 TGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKV 374 TG D V +W + T + G T+ V S++F + + G+ G +K+WD+ + K Sbjct: 355 TGAADAVVKIWDLKNQTVAAAFPGHTAAVRSIAFSENGYYLATGSEDGEVKLWDLRKLKN 414 Query: 375 VRTFTG-HRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFT 551 ++TF + SL G F G +++ ++ + + H+G + +RF Sbjct: 415 LKTFANEEKQPINSLSFDMTGTFLGIGGQ--KVQVLHVKSWSEVVSLSDHSGPVTGVRFG 472 Query: 552 PDGRWIVSGGADSSVK 599 + R +V+ D S++ Sbjct: 473 ENARSLVTCSLDKSLR 488 Score = 46.2 bits (108), Expect = 7e-05 Identities = 31/139 (22%), Positives = 58/139 (41%), Gaps = 3/139 (2%) Frame = +3 Query: 192 ITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAK 371 +TGG D+ V L+ K + + G + ++ + + +A I++W ++ Sbjct: 225 LTGGIDKTVVLYDYEKEQVMQTFKGHNKKINAVVLHPDNITAISASADSHIRVWSATDSS 284 Query: 372 VVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMR--KKRC-IHTYQGHTGRIDVL 542 H++ + + GD+ S S D+ D+R K C + G + + Sbjct: 285 SKAIIDVHQAPVTDISLNASGDYILSASDDSYWAFSDIRSGKSLCKVSVEPGSQIAVHSI 344 Query: 543 RFTPDGRWIVSGGADSSVK 599 F PDG +G AD+ VK Sbjct: 345 EFHPDGLIFGTGAADAVVK 363 Score = 41.2 bits (95), Expect = 0.002 Identities = 27/110 (24%), Positives = 49/110 (44%), Gaps = 4/110 (3%) Frame = +3 Query: 282 ESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSN----CASLDSHPFGDFFAS 449 +S S + G G K ++ E K + TG S +LD G+ + Sbjct: 169 KSKSLTAERKQRGKNLPEGLAKTEELAELKQTASHTGIHSTGTPGITALDIK--GNLSLT 226 Query: 450 GSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 G D + ++D K++ + T++GH +I+ + PD +S ADS ++ Sbjct: 227 GGIDKTVVLYDYEKEQVMQTFKGHNKKINAVVLHPDNITAISASADSHIR 276
>WDR48_MACFA (Q4R2Z6) WD-repeat protein 48| Length = 622 Score = 64.7 bits (156), Expect = 2e-10 Identities = 39/143 (27%), Positives = 67/143 (46%), Gaps = 9/143 (6%) Frame = +3 Query: 195 TGGEDQKVNLWAVGKPTAVL---------SLSGLTSPVESLSFDSSEVMIGAGAASGTIK 347 + G D+++ LW V TA+ SLSG + SL+ + +I +G+ ++ Sbjct: 134 SAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLR 193 Query: 348 IWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTG 527 +WD + GH N +L + G SGSSD +++W + ++RCI TY+ H Sbjct: 194 VWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDE 253 Query: 528 RIDVLRFTPDGRWIVSGGADSSV 596 + L+ + SGG D + Sbjct: 254 GVWALQVNDAFTHVYSGGRDRKI 276 Score = 59.3 bits (142), Expect = 8e-09 Identities = 32/148 (21%), Positives = 67/148 (45%), Gaps = 9/148 (6%) Frame = +3 Query: 183 RTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIE 362 +TLI+ D V +W K + +L V++L++ + ++ + I +WD+ Sbjct: 88 KTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVN 147 Query: 363 EAKVVR---------TFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQ 515 + + +G++ + SL + G SGS++ +++WD R + + Sbjct: 148 TLTALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLK 207 Query: 516 GHTGRIDVLRFTPDGRWIVSGGADSSVK 599 GHT + L DG +SG +D +++ Sbjct: 208 GHTDNVKALLLNRDGTQCLSGSSDGTIR 235 Score = 42.0 bits (97), Expect = 0.001 Identities = 25/109 (22%), Positives = 43/109 (39%), Gaps = 3/109 (2%) Frame = +3 Query: 279 VESLSFDSSEVMIGAGAASGTIKIWDIEEAK---VVRTFTGHRSNCASLDSHPFGDFFAS 449 V +L D + + I+IW + + K + + H + G S Sbjct: 33 VNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDIVLCCNGKTLIS 92 Query: 450 GSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 SSDT +K+W+ K C+ T + H + L + D + S G D + Sbjct: 93 ASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQI 141 Score = 41.2 bits (95), Expect = 0.002 Identities = 24/102 (23%), Positives = 46/102 (45%), Gaps = 1/102 (0%) Frame = +3 Query: 186 TLITGGEDQKV-NLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIE 362 T+I G +KV +W ++ L G T V++L + +G++ GTI++W + Sbjct: 181 TIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLG 240 Query: 363 EAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMR 488 + + + T+ H +L + SG D + D+R Sbjct: 241 QQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLR 282
>PWP2_YEAST (P25635) Periodic tryptophan protein 2 (U3 small nucleolar| RNA-associated protein 1) (U3 snoRNA-associated protein 1) Length = 923 Score = 64.7 bits (156), Expect = 2e-10 Identities = 34/141 (24%), Positives = 70/141 (49%), Gaps = 4/141 (2%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 ++T ED K+ +W + + + TS V ++ F ++ + + GT++ WD+ Sbjct: 360 VVTASEDGKIKVWDITSGFCLATFEEHTSSVTAVQFAKRGQVMFSSSLDGTVRAWDLIRY 419 Query: 369 KVVRTFTGH---RSNCASLDSHPFGDFFASGSSDT-NMKIWDMRKKRCIHTYQGHTGRID 536 + RTFTG + NC ++D P G+ +GS D ++ +W ++ + + GH G + Sbjct: 420 RNFRTFTGTERIQFNCLAVD--PSGEVVCAGSLDNFDIHVWSVQTGQLLDALSGHEGPVS 477 Query: 537 VLRFTPDGRWIVSGGADSSVK 599 L F+ + + S D +++ Sbjct: 478 CLSFSQENSVLASASWDKTIR 498 Score = 60.8 bits (146), Expect = 3e-09 Identities = 40/165 (24%), Positives = 75/165 (45%), Gaps = 1/165 (0%) Frame = +3 Query: 108 RAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVES 287 R K F A+ + V C F T R L G + L+ + T + LS +PV + Sbjct: 249 RITKKHFFYANQAKVKCVTFHPAT-RLLAVGFTSGEFRLYDLPDFTLIQQLSMGQNPVNT 307 Query: 288 LSFDSSEVMIGAGAAS-GTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDT 464 +S + + + G++ G + +++ + + GH + SL P G + S D Sbjct: 308 VSVNQTGEWLAFGSSKLGQLLVYEWQSESYILKQQGHFDSTNSLAYSPDGSRVVTASEDG 367 Query: 465 NMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 +K+WD+ C+ T++ HT + ++F G+ + S D +V+ Sbjct: 368 KIKVWDITSGFCLATFEEHTSSVTAVQFAKRGQVMFSSSLDGTVR 412 Score = 49.3 bits (116), Expect = 8e-06 Identities = 31/116 (26%), Positives = 50/116 (43%), Gaps = 2/116 (1%) Frame = +3 Query: 249 VLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHP 428 +L G SL++ + + G IK+WDI + TF H S+ ++ Sbjct: 338 ILKQQGHFDSTNSLAYSPDGSRVVTASEDGKIKVWDITSGFCLATFEEHTSSVTAVQFAK 397 Query: 429 FGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRI--DVLRFTPDGRWIVSGGADS 590 G S S D ++ WD+ + R T+ G T RI + L P G + +G D+ Sbjct: 398 RGQVMFSSSLDGTVRAWDLIRYRNFRTFTG-TERIQFNCLAVDPSGEVVCAGSLDN 452 Score = 42.0 bits (97), Expect = 0.001 Identities = 29/124 (23%), Positives = 52/124 (41%), Gaps = 2/124 (1%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTS-PVESLSF 296 L F H S VT +F KR + + + D V W + + + +G L+ Sbjct: 380 LATFEEHTSSVTAVQFAKR-GQVMFSSSLDGTVRAWDLIRYRNFRTFTGTERIQFNCLAV 438 Query: 297 DSSEVMIGAGAASG-TIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMK 473 D S ++ AG+ I +W ++ +++ +GH + L AS S D ++ Sbjct: 439 DPSGEVVCAGSLDNFDIHVWSVQTGQLLDALSGHEGPVSCLSFSQENSVLASASWDKTIR 498 Query: 474 IWDM 485 IW + Sbjct: 499 IWSI 502 Score = 35.8 bits (81), Expect = 0.097 Identities = 33/151 (21%), Positives = 64/151 (42%), Gaps = 24/151 (15%) Frame = +3 Query: 216 VNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDI----EEAKVVRT 383 +++W+V + +LSG PV LSF ++ + + TI+IW I ++ + + Sbjct: 455 IHVWSVQTGQLLDALSGHEGPVSCLSFSQENSVLASASWDKTIRIWSIFGRSQQVEPIEV 514 Query: 384 FTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGH----TGRIDVLRFT 551 + S+ +L P G A + + I+++ + + +GR + RFT Sbjct: 515 Y----SDVLALSMRPDGKEVAVSTLKGQISIFNIEDAKQVGNIDCRKDIISGRFNQDRFT 570 Query: 552 P----------------DGRWIVSGGADSSV 596 DG IV+GG ++S+ Sbjct: 571 AKNSERSKFFTTIHYSFDGMAIVAGGNNNSI 601
>WDR48_PONPY (Q5RAW8) WD-repeat protein 48| Length = 677 Score = 64.7 bits (156), Expect = 2e-10 Identities = 39/143 (27%), Positives = 67/143 (46%), Gaps = 9/143 (6%) Frame = +3 Query: 195 TGGEDQKVNLWAVGKPTAVL---------SLSGLTSPVESLSFDSSEVMIGAGAASGTIK 347 + G D+++ LW V TA+ SLSG + SL+ + +I +G+ ++ Sbjct: 134 SAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLR 193 Query: 348 IWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTG 527 +WD + GH N +L + G SGSSD +++W + ++RCI TY+ H Sbjct: 194 VWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDE 253 Query: 528 RIDVLRFTPDGRWIVSGGADSSV 596 + L+ + SGG D + Sbjct: 254 GVWALQVNDAFTHVYSGGRDRKI 276 Score = 59.3 bits (142), Expect = 8e-09 Identities = 32/148 (21%), Positives = 67/148 (45%), Gaps = 9/148 (6%) Frame = +3 Query: 183 RTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIE 362 +TLI+ D V +W K + +L V++L++ + ++ + I +WD+ Sbjct: 88 KTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVN 147 Query: 363 EAKVVR---------TFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQ 515 + + +G++ + SL + G SGS++ +++WD R + + Sbjct: 148 TLTALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLK 207 Query: 516 GHTGRIDVLRFTPDGRWIVSGGADSSVK 599 GHT + L DG +SG +D +++ Sbjct: 208 GHTDNVKALLLNRDGTQCLSGSSDGTIR 235 Score = 42.0 bits (97), Expect = 0.001 Identities = 25/109 (22%), Positives = 43/109 (39%), Gaps = 3/109 (2%) Frame = +3 Query: 279 VESLSFDSSEVMIGAGAASGTIKIWDIEEAK---VVRTFTGHRSNCASLDSHPFGDFFAS 449 V +L D + + I+IW + + K + + H + G S Sbjct: 33 VNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDIVLCCNGKTLIS 92 Query: 450 GSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 SSDT +K+W+ K C+ T + H + L + D + S G D + Sbjct: 93 ASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQI 141 Score = 41.2 bits (95), Expect = 0.002 Identities = 24/102 (23%), Positives = 46/102 (45%), Gaps = 1/102 (0%) Frame = +3 Query: 186 TLITGGEDQKV-NLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIE 362 T+I G +KV +W ++ L G T V++L + +G++ GTI++W + Sbjct: 181 TIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLG 240 Query: 363 EAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMR 488 + + + T+ H +L + SG D + D+R Sbjct: 241 QQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLR 282
>WDR48_HUMAN (Q8TAF3) WD-repeat protein 48 (WD repeat endosomal protein) (p80)| Length = 677 Score = 64.7 bits (156), Expect = 2e-10 Identities = 39/143 (27%), Positives = 67/143 (46%), Gaps = 9/143 (6%) Frame = +3 Query: 195 TGGEDQKVNLWAVGKPTAVL---------SLSGLTSPVESLSFDSSEVMIGAGAASGTIK 347 + G D+++ LW V TA+ SLSG + SL+ + +I +G+ ++ Sbjct: 134 SAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLR 193 Query: 348 IWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTG 527 +WD + GH N +L + G SGSSD +++W + ++RCI TY+ H Sbjct: 194 VWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDE 253 Query: 528 RIDVLRFTPDGRWIVSGGADSSV 596 + L+ + SGG D + Sbjct: 254 GVWALQVNDAFTHVYSGGRDRKI 276 Score = 59.3 bits (142), Expect = 8e-09 Identities = 32/148 (21%), Positives = 67/148 (45%), Gaps = 9/148 (6%) Frame = +3 Query: 183 RTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIE 362 +TLI+ D V +W K + +L V++L++ + ++ + I +WD+ Sbjct: 88 KTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVN 147 Query: 363 EAKVVR---------TFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQ 515 + + +G++ + SL + G SGS++ +++WD R + + Sbjct: 148 TLTALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLK 207 Query: 516 GHTGRIDVLRFTPDGRWIVSGGADSSVK 599 GHT + L DG +SG +D +++ Sbjct: 208 GHTDNVKALLLNRDGTQCLSGSSDGTIR 235 Score = 42.0 bits (97), Expect = 0.001 Identities = 25/109 (22%), Positives = 43/109 (39%), Gaps = 3/109 (2%) Frame = +3 Query: 279 VESLSFDSSEVMIGAGAASGTIKIWDIEEAK---VVRTFTGHRSNCASLDSHPFGDFFAS 449 V +L D + + I+IW + + K + + H + G S Sbjct: 33 VNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDIVLCCNGKTLIS 92 Query: 450 GSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 SSDT +K+W+ K C+ T + H + L + D + S G D + Sbjct: 93 ASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQI 141 Score = 41.2 bits (95), Expect = 0.002 Identities = 24/102 (23%), Positives = 46/102 (45%), Gaps = 1/102 (0%) Frame = +3 Query: 186 TLITGGEDQKV-NLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIE 362 T+I G +KV +W ++ L G T V++L + +G++ GTI++W + Sbjct: 181 TIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLG 240 Query: 363 EAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMR 488 + + + T+ H +L + SG D + D+R Sbjct: 241 QQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLR 282
>TLE1_BRARE (O13168) Groucho 1 protein (Fragment)| Length = 535 Score = 64.3 bits (155), Expect = 3e-10 Identities = 37/141 (26%), Positives = 64/141 (45%), Gaps = 2/141 (1%) Frame = +3 Query: 183 RTLITGGEDQKVNLWAVGKPTAVLS--LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWD 356 RTLI GGE + +W + T + L+ +L+ + + + G I +WD Sbjct: 308 RTLIAGGEVSTLTIWDLASQTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWD 367 Query: 357 IEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRID 536 + +VR F GH + +D G +G D ++ WD+R+ R + + T +I Sbjct: 368 LHNQTLVRQFQGHTDGASCIDISHDGPKLWTGGLDNTVRSWDLREGRQLQQHD-FTSQIF 426 Query: 537 VLRFTPDGRWIVSGGADSSVK 599 L + P G W+ G S+V+ Sbjct: 427 SLGYCPTGEWLAVGMESSNVE 447 Score = 57.0 bits (136), Expect = 4e-08 Identities = 39/158 (24%), Positives = 71/158 (44%), Gaps = 7/158 (4%) Frame = +3 Query: 147 DVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVM---- 314 +V CA +R + TGG+ V +W + +P + +S L S +++ Sbjct: 250 EVVCAVTISNPTRHVYTGGKGC-VKIWDISQPGSKSPVSQLDCLNRDNYIRSCKLLPDGR 308 Query: 315 -IGAGAASGTIKIWDI--EEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDM 485 + AG T+ IWD+ + ++ T C +L P S SD N+ +WD+ Sbjct: 309 TLIAGGEVSTLTIWDLASQTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDL 368 Query: 486 RKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 + + +QGHT + + DG + +GG D++V+ Sbjct: 369 HNQTLVRQFQGHTDGASCIDISHDGPKLWTGGLDNTVR 406
>UTP15_MOUSE (Q8C7V3) U3 small nucleolar RNA-associated protein 15 homolog| (Src-associated protein SAW) Length = 528 Score = 64.3 bits (155), Expect = 3e-10 Identities = 44/146 (30%), Positives = 71/146 (48%), Gaps = 4/146 (2%) Frame = +3 Query: 156 CAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAAS 335 CA F ++ + L+ G ED V L+ + + G T V ++ F + + +GA Sbjct: 85 CATF-RQDGQLLVAGSEDGVVQLFDINGRAPLRQFEGHTKAVHTVDFTADNYHVVSGADD 143 Query: 336 GTIKIWDIEEAKVVRTFTGH----RSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCI 503 T+K+WDI +K + TF H R CAS +P D F +GS D +KI+D R + + Sbjct: 144 YTVKLWDIPNSKEILTFKEHSDYVRCGCAS-KLNP--DLFVTGSYDHTVKIFDARTNKNV 200 Query: 504 HTYQGHTGRIDVLRFTPDGRWIVSGG 581 + H ++ + P G +VS G Sbjct: 201 LCVE-HGQPVESVLLFPSGGLLVSAG 225 Score = 45.1 bits (105), Expect = 2e-04 Identities = 25/93 (26%), Positives = 44/93 (47%) Frame = +3 Query: 321 AGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRC 500 A AS I I+ + V+TF+ + G +GS D ++++D+ + Sbjct: 55 AVTASSRIHIYGRYSQEPVKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDINGRAP 114 Query: 501 IHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 + ++GHT + + FT D +VSG D +VK Sbjct: 115 LRQFEGHTKAVHTVDFTADNYHVVSGADDYTVK 147 Score = 42.4 bits (98), Expect = 0.001 Identities = 32/130 (24%), Positives = 55/130 (42%), Gaps = 2/130 (1%) Frame = +3 Query: 129 FVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVES-LSFDSS 305 F H+ V C K +TG D V ++ VL + PVES L F S Sbjct: 160 FKEHSDYVRCGCASKLNPDLFVTGSYDHTVKIFDARTNKNVLCVEH-GQPVESVLLFPSG 218 Query: 306 EVMIGAGAASGTIKIWD-IEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 +++ AG +K+WD ++ +++ + H L G SGS D +K++ Sbjct: 219 GLLVSAGGRY--VKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYS 276 Query: 483 MRKKRCIHTY 512 + +H++ Sbjct: 277 TTSYKVVHSF 286
>TBL1R_MOUSE (Q8BHJ5) F-box-like/WD-repeat protein TBL1XR1 (Transducin beta-like| 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1) Length = 514 Score = 63.9 bits (154), Expect = 3e-10 Identities = 37/168 (22%), Positives = 79/168 (47%), Gaps = 9/168 (5%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 ++ F H ++V K+ T L + +D + +W++ + V L + ++ + Sbjct: 342 IKTFQGHTNEVNAIKWDP-TGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWS 400 Query: 300 ---------SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASG 452 ++ +M+ + + T+++WD++ + T T H+ S+ P G + ASG Sbjct: 401 PTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASG 460 Query: 453 SSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 S D + IW+ + +H+Y+G TG I + + G + + +D SV Sbjct: 461 SFDKCVHIWNTQTGALVHSYRG-TGGIFEVCWNAAGDKVGASASDGSV 507 Score = 60.1 bits (144), Expect = 5e-09 Identities = 34/157 (21%), Positives = 68/157 (43%) Frame = +3 Query: 90 SRMATKRAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGL 269 +R+ TK H + K+ K+ +++ G D+ +W A Sbjct: 249 ARIWTKDGNLASTLGQHKGPIFALKWNKK-GNFILSAGVDKTTIIWDAHTGEAKQQFPFH 307 Query: 270 TSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFAS 449 ++P + + S+ + I + + + + ++TF GH + ++ P G+ AS Sbjct: 308 SAPALDVDWQSNNTFASC-STDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLAS 366 Query: 450 GSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDG 560 S D +KIW M++ C+H Q H I ++++P G Sbjct: 367 CSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTG 403 Score = 49.7 bits (117), Expect = 6e-06 Identities = 34/137 (24%), Positives = 60/137 (43%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L TG D +W A +L P+ +L ++ I + T IWD Sbjct: 240 LATGSYDGFARIWTKDGNLAS-TLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTG 298 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 + + F H + +D + FAS S+D + + + + R I T+QGHT ++ +++ Sbjct: 299 EAKQQFPFHSAPALDVDWQS-NNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKW 357 Query: 549 TPDGRWIVSGGADSSVK 599 P G + S D ++K Sbjct: 358 DPTGNLLASCSDDMTLK 374 Score = 36.2 bits (82), Expect = 0.074 Identities = 30/126 (23%), Positives = 51/126 (40%), Gaps = 14/126 (11%) Frame = +3 Query: 258 LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKV---VRTFTGH----------- 395 L G S V +++ ++ +G+ T +IW++ E + H Sbjct: 165 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGPTQLVLRHCIREGGQDVPS 224 Query: 396 RSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVS 575 + SLD + G A+GS D +IW + T H G I L++ G +I+S Sbjct: 225 NKDVTSLDWNSEGTLLATGSYDGFARIW-TKDGNLASTLGQHKGPIFALKWNKKGNFILS 283 Query: 576 GGADSS 593 G D + Sbjct: 284 AGVDKT 289
>TBL1R_HUMAN (Q9BZK7) F-box-like/WD-repeat protein TBL1XR1 (Transducin beta-like| 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1) Length = 514 Score = 63.9 bits (154), Expect = 3e-10 Identities = 37/168 (22%), Positives = 79/168 (47%), Gaps = 9/168 (5%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 ++ F H ++V K+ T L + +D + +W++ + V L + ++ + Sbjct: 342 IKTFQGHTNEVNAIKWDP-TGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWS 400 Query: 300 ---------SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASG 452 ++ +M+ + + T+++WD++ + T T H+ S+ P G + ASG Sbjct: 401 PTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASG 460 Query: 453 SSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 S D + IW+ + +H+Y+G TG I + + G + + +D SV Sbjct: 461 SFDKCVHIWNTQTGALVHSYRG-TGGIFEVCWNAAGDKVGASASDGSV 507 Score = 60.1 bits (144), Expect = 5e-09 Identities = 34/157 (21%), Positives = 68/157 (43%) Frame = +3 Query: 90 SRMATKRAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGL 269 +R+ TK H + K+ K+ +++ G D+ +W A Sbjct: 249 ARIWTKDGNLASTLGQHKGPIFALKWNKK-GNFILSAGVDKTTIIWDAHTGEAKQQFPFH 307 Query: 270 TSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFAS 449 ++P + + S+ + I + + + + ++TF GH + ++ P G+ AS Sbjct: 308 SAPALDVDWQSNNTFASC-STDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLAS 366 Query: 450 GSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDG 560 S D +KIW M++ C+H Q H I ++++P G Sbjct: 367 CSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTG 403 Score = 49.7 bits (117), Expect = 6e-06 Identities = 34/137 (24%), Positives = 60/137 (43%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L TG D +W A +L P+ +L ++ I + T IWD Sbjct: 240 LATGSYDGFARIWTKDGNLAS-TLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTG 298 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 + + F H + +D + FAS S+D + + + + R I T+QGHT ++ +++ Sbjct: 299 EAKQQFPFHSAPALDVDWQS-NNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKW 357 Query: 549 TPDGRWIVSGGADSSVK 599 P G + S D ++K Sbjct: 358 DPTGNLLASCSDDMTLK 374 Score = 38.5 bits (88), Expect = 0.015 Identities = 31/132 (23%), Positives = 53/132 (40%), Gaps = 14/132 (10%) Frame = +3 Query: 240 PTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNC---- 407 P + L G S V +++ ++ +G+ T +IW++ E + +C Sbjct: 159 PNKAVVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREG 218 Query: 408 ----------ASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPD 557 SLD + G A+GS D +IW + T H G I L++ Sbjct: 219 GQDVPSNKDVTSLDWNSEGTLLATGSYDGFARIW-TKDGNLASTLGQHKGPIFALKWNKK 277 Query: 558 GRWIVSGGADSS 593 G +I+S G D + Sbjct: 278 GNFILSAGVDKT 289
>WDR47_HUMAN (O94967) WD-repeat protein 47| Length = 919 Score = 63.9 bits (154), Expect = 3e-10 Identities = 36/119 (30%), Positives = 63/119 (52%), Gaps = 4/119 (3%) Frame = +3 Query: 255 SLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVR----TFTGHRSNCASLDS 422 +LSG T + +L + S MI +G+ T++ WD+ VR TF G S AS+ Sbjct: 750 ALSGHTGHILAL-YTWSGWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAV 808 Query: 423 HPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 P G A+G D++ ++D+R R + +Y H+ + +RF+P ++++G D +K Sbjct: 809 DPSGRLLATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIK 867 Score = 49.7 bits (117), Expect = 6e-06 Identities = 40/166 (24%), Positives = 65/166 (39%), Gaps = 14/166 (8%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAV-----LSLSGLTSPVESLSF-- 296 H + C + + L TG D+ V + T L S + L+F Sbjct: 660 HKGSIYCVAWSP-CGQLLATGSNDKYVKVLPFNAETCNATGPDLEFSMHDGTIRDLAFME 718 Query: 297 ---DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTN 467 ++I AGA I D + + + +GH + +L + G ASGS D Sbjct: 719 GPESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHILALYTWS-GWMIASGSQDKT 777 Query: 468 MKIWDMRKKRCIH----TYQGHTGRIDVLRFTPDGRWIVSGGADSS 593 ++ WD+R C+ T+ G + + P GR + +G DSS Sbjct: 778 VRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSS 823
>GBB_MAIZE (P49178) Guanine nucleotide-binding protein beta subunit| Length = 380 Score = 63.9 bits (154), Expect = 3e-10 Identities = 47/161 (29%), Positives = 76/161 (47%), Gaps = 14/161 (8%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAV--GKPTAVLS---LSGLTSPVESLSFDS 302 H V+ ++ LIT DQ LW V G+ ++ SG T+ V+S+S +S Sbjct: 156 HKGYVSSCQYVPDQETRLITSSGDQTCVLWDVTTGQRISIFGGEFPSGHTADVQSVSINS 215 Query: 303 SEV-MIGAGAASGTIKIWDIEEA-KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 S M +G+ T+++WDI A + VRT+ GH + S+ P G F +GS D ++ Sbjct: 216 SNTNMFVSGSCDTTVRLWDIRIASRAVRTYHGHEDDVNSVKFFPDGHRFGTGSDDGTCRL 275 Query: 477 WDMRKKRCIHTYQGHTGR-------IDVLRFTPDGRWIVSG 578 +DMR + Y R + + F+ GR + +G Sbjct: 276 FDMRTGHQLQVYSREPDRNSNELPTVTSIAFSISGRLLFAG 316 Score = 53.5 bits (127), Expect = 4e-07 Identities = 32/122 (26%), Positives = 58/122 (47%), Gaps = 8/122 (6%) Frame = +3 Query: 258 LSGLTSPVESLSF-DSSEVMIGAGAASGTIKIWDIEEAKVVRTF-----TGHRSNCASLD 419 L+G V S + E + + T +WD+ + + F +GH ++ S+ Sbjct: 153 LTGHKGYVSSCQYVPDQETRLITSSGDQTCVLWDVTTGQRISIFGGEFPSGHTADVQSVS 212 Query: 420 SHPFG-DFFASGSSDTNMKIWDMR-KKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSS 593 + + F SGS DT +++WD+R R + TY GH ++ ++F PDG +G D + Sbjct: 213 INSSNTNMFVSGSCDTTVRLWDIRIASRAVRTYHGHEDDVNSVKFFPDGHRFGTGSDDGT 272 Query: 594 VK 599 + Sbjct: 273 CR 274 Score = 42.0 bits (97), Expect = 0.001 Identities = 21/72 (29%), Positives = 33/72 (45%) Frame = +3 Query: 378 RTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPD 557 RT GH SLD P ++ S S D + +W+ + H + H + F P+ Sbjct: 60 RTLQGHSGKVYSLDWTPEKNWIVSASQDGRLIVWNALTSQKTHAIKLHCPWVMACAFAPN 119 Query: 558 GRWIVSGGADSS 593 G+ + GG DS+ Sbjct: 120 GQSVACGGLDSA 131 Score = 37.7 bits (86), Expect = 0.026 Identities = 32/121 (26%), Positives = 45/121 (37%), Gaps = 4/121 (3%) Frame = +3 Query: 129 FVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSE 308 F + D TC F RT L + N S V S++F S Sbjct: 264 FGTGSDDGTCRLFDMRTGHQLQVYSREPDRN-------------SNELPTVTSIAFSISG 310 Query: 309 VMIGAGAASGTIKIWDIEEAKVVRTF----TGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 ++ AG ++G +WD A+VV H + L G +GS D N+KI Sbjct: 311 RLLFAGYSNGDCYVWDTLLAEVVLNLGNLQNSHDGRISCLGMSSDGSALCTGSWDKNLKI 370 Query: 477 W 479 W Sbjct: 371 W 371 Score = 35.8 bits (81), Expect = 0.097 Identities = 14/30 (46%), Positives = 19/30 (63%) Frame = +3 Query: 498 CIHTYQGHTGRIDVLRFTPDGRWIVSGGAD 587 C T QGH+G++ L +TP+ WIVS D Sbjct: 58 CCRTLQGHSGKVYSLDWTPEKNWIVSASQD 87
>WDR47_MOUSE (Q8CGF6) WD-repeat protein 47| Length = 920 Score = 63.9 bits (154), Expect = 3e-10 Identities = 36/119 (30%), Positives = 63/119 (52%), Gaps = 4/119 (3%) Frame = +3 Query: 255 SLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVR----TFTGHRSNCASLDS 422 +LSG T + +L + S MI +G+ T++ WD+ VR TF G S AS+ Sbjct: 751 ALSGHTGHILAL-YTWSGWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAV 809 Query: 423 HPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 P G A+G D++ ++D+R R + +Y H+ + +RF+P ++++G D +K Sbjct: 810 DPSGRLLATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIK 868 Score = 49.7 bits (117), Expect = 6e-06 Identities = 40/166 (24%), Positives = 65/166 (39%), Gaps = 14/166 (8%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAV-----LSLSGLTSPVESLSF-- 296 H + C + + L TG D+ V + T L S + L+F Sbjct: 661 HKGSIYCVAWSP-CGQLLATGSNDKYVKVLPFNAETCNATGPDLEFSMHDGTIRDLAFME 719 Query: 297 ---DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTN 467 ++I AGA I D + + + +GH + +L + G ASGS D Sbjct: 720 GPESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHILALYTWS-GWMIASGSQDKT 778 Query: 468 MKIWDMRKKRCIH----TYQGHTGRIDVLRFTPDGRWIVSGGADSS 593 ++ WD+R C+ T+ G + + P GR + +G DSS Sbjct: 779 VRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSS 824
>WSB2_MOUSE (O54929) WD repeat and SOCS box-containing protein 2 (WSB-2) (SOCS| box-containing WD protein SWiP-2) Length = 404 Score = 63.9 bits (154), Expect = 3e-10 Identities = 43/154 (27%), Positives = 69/154 (44%), Gaps = 2/154 (1%) Frame = +3 Query: 141 ASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIG 320 A DV+C L TG D ++ +W V +L+LSG V LSF S +I Sbjct: 118 APDVSCL--------ILATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLIL 169 Query: 321 AGAASG-TIKIWDIEE-AKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKK 494 A+ T++IWD+ + K ++ +GH P S + + ++ +W MR Sbjct: 170 VSASRDKTLRIWDLNKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSY 229 Query: 495 RCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 I +GH + F+PD +V+ D+SV Sbjct: 230 TLIRKLEGHQSSVVSCDFSPDSALLVTASYDTSV 263 Score = 46.6 bits (109), Expect = 5e-05 Identities = 36/163 (22%), Positives = 66/163 (40%), Gaps = 13/163 (7%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLS-LSGLTSPVESLSFDSSEVM 314 H V F S L++ D+ + +W + K + LSG V S M Sbjct: 152 HQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNKHGKQIQVLSGHLQWVYCCSISPDCSM 211 Query: 315 IGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDM--- 485 + + A ++ +W + ++R GH+S+ S D P + S DT++ +WD Sbjct: 212 LCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCDFSPDSALLVTASYDTSVIMWDPYTG 271 Query: 486 RKKRCIHTYQ---------GHTGRIDVLRFTPDGRWIVSGGAD 587 + R +H Q H + + F+P+G ++ + D Sbjct: 272 ARLRSLHHTQLEPTMDDSDVHMSSLRSVCFSPEGLYLATVADD 314
>GBB_SCHPO (Q10282) Guanine nucleotide-binding protein beta subunit| Length = 305 Score = 63.5 bits (153), Expect = 4e-10 Identities = 45/149 (30%), Positives = 69/149 (46%), Gaps = 3/149 (2%) Frame = +3 Query: 150 VTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTA-VLSLSGLTSPVESLSF-DSSEVMIGA 323 +TCA F T +++ GG + ++ P A + L G V + D ++ G+ Sbjct: 67 MTCA-FSPST-KSIAAGGLNNFCVVYDTSVPDADPVELVGHAGFVSCCKYVDDGHLLTGS 124 Query: 324 GAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFG-DFFASGSSDTNMKIWDMRKKRC 500 G T WDIE+AK + GH + SLD P + F +G D K+WD+R C Sbjct: 125 G--DKTCMFWDIEQAKAISVLKGHEMDIVSLDFLPSNPNLFVTGGCDKLAKLWDLRAAYC 182 Query: 501 IHTYQGHTGRIDVLRFTPDGRWIVSGGAD 587 T+ G+T I+ + F P V+G D Sbjct: 183 CATFPGNTSDINSISFFPSNADFVTGAED 211 Score = 59.3 bits (142), Expect = 8e-09 Identities = 43/172 (25%), Positives = 67/172 (38%), Gaps = 7/172 (4%) Frame = +3 Query: 105 KRAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVE 284 ++A + H D+ F +TGG D+ LW + + G TS + Sbjct: 135 EQAKAISVLKGHEMDIVSLDFLPSNPNLFVTGGCDKLAKLWDLRAAYCCATFPGNTSDIN 194 Query: 285 SLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGD--FFASG-- 452 S+SF S GA G + +DI + + + +S S P F SG Sbjct: 195 SISFFPSNADFVTGAEDGIARCFDIRASAEIFQY-------SSPSSSPINSVLFSKSGKL 247 Query: 453 ---SSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 + D ++WD + I + GH RI L T DG + +G D V+ Sbjct: 248 LFIAKDKTCEVWDSISSKTITSLTGHENRISSLALTSDGTMLATGSWDECVR 299 Score = 48.9 bits (115), Expect = 1e-05 Identities = 32/126 (25%), Positives = 57/126 (45%), Gaps = 1/126 (0%) Frame = +3 Query: 105 KRAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSG-LTSPV 281 + AY F + SD+ F ++ +TG ED + + + S +SP+ Sbjct: 178 RAAYCCATFPGNTSDINSISFFP-SNADFVTGAEDGIARCFDIRASAEIFQYSSPSSSPI 236 Query: 282 ESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSD 461 S+ F S ++ A T ++WD +K + + TGH + +SL G A+GS D Sbjct: 237 NSVLFSKSGKLLFI-AKDKTCEVWDSISSKTITSLTGHENRISSLALTSDGTMLATGSWD 295 Query: 462 TNMKIW 479 +++W Sbjct: 296 ECVRLW 301
>PWP2_HUMAN (Q15269) Periodic tryptophan protein 2 homolog| Length = 919 Score = 63.2 bits (152), Expect = 6e-10 Identities = 36/141 (25%), Positives = 72/141 (51%), Gaps = 4/141 (2%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 ++TGG+D KV +W ++ + +S V ++F ++ ++ + GT++ +D+ Sbjct: 388 IVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAFDLHRY 447 Query: 369 KVVRTFTGHRS---NCASLDSHPFGDFFASGSSDT-NMKIWDMRKKRCIHTYQGHTGRID 536 + RTFT R +C ++D+ G+ ++G+ D+ + +W M+ R + GH G I Sbjct: 448 RNFRTFTSPRPTQFSCVAVDAS--GEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPIS 505 Query: 537 VLRFTPDGRWIVSGGADSSVK 599 L F P + S D +V+ Sbjct: 506 GLCFNPMKSVLASASWDKTVR 526 Score = 58.9 bits (141), Expect = 1e-08 Identities = 38/153 (24%), Positives = 72/153 (47%), Gaps = 1/153 (0%) Frame = +3 Query: 144 SDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGA 323 +++T A F K+ S L+TG +L + + + SLS + S++ +SS I Sbjct: 289 NNLTAAAFHKK-SHLLVTGFASGIFHLHELPEFNLIHSLSISDQSIASVAINSSGDWIAF 347 Query: 324 GAAS-GTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRC 500 G + G + +W+ + V GH ++ +L P G + +G D +K+W+ C Sbjct: 348 GCSGLGQLLVWEWQSESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFC 407 Query: 501 IHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 T+ H+ + + FT G +V+ D +V+ Sbjct: 408 FVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVR 440 Score = 44.3 bits (103), Expect = 3e-04 Identities = 38/161 (23%), Positives = 66/161 (40%), Gaps = 5/161 (3%) Frame = +3 Query: 129 FVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSP----VESLSF 296 F H+S VT F T ++T D V + + + + TSP ++ Sbjct: 411 FTEHSSGVTGVTF-TATGYVVVTSSMDGTVRAFDLHR---YRNFRTFTSPRPTQFSCVAV 466 Query: 297 DSSEVMIGAGAA-SGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMK 473 D+S ++ AGA S I +W ++ +++ +GH + L +P AS S D ++ Sbjct: 467 DASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVR 526 Query: 474 IWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 +WDM T + F PDG + +S + Sbjct: 527 LWDMFDSWRTKETLALTSDALAVTFRPDGAELAVATLNSQI 567 Score = 36.2 bits (82), Expect = 0.074 Identities = 25/124 (20%), Positives = 47/124 (37%), Gaps = 1/124 (0%) Frame = +3 Query: 222 LWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRS 401 +W + VL G + + +L++ I G G +K+W+ TFT H S Sbjct: 357 VWEWQSESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSS 416 Query: 402 NCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQG-HTGRIDVLRFTPDGRWIVSG 578 + G + S D ++ +D+ + R T+ + + G + +G Sbjct: 417 GVTGVTFTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAG 476 Query: 579 GADS 590 DS Sbjct: 477 AQDS 480 Score = 35.4 bits (80), Expect = 0.13 Identities = 29/154 (18%), Positives = 65/154 (42%), Gaps = 21/154 (13%) Frame = +3 Query: 198 GGEDQ-KVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKV 374 G +D ++ +W++ + LSG P+ L F+ + ++ + + T+++WD+ ++ Sbjct: 476 GAQDSFEIFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDMFDSWR 535 Query: 375 VRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGH----TGRIDV- 539 + S+ ++ P G A + ++ + WD + +G TGR ++ Sbjct: 536 TKETLALTSDALAVTFRPDGAELAVATLNSQITFWDPENAVQTGSIEGRHDLKTGRKELD 595 Query: 540 ---------------LRFTPDGRWIVSGGADSSV 596 L ++ DG I++GG V Sbjct: 596 KITAKHAAKGKAFTALCYSADGHSILAGGMSKFV 629
>TLE2_HUMAN (Q04725) Transducin-like enhancer protein 2 (ESG2)| Length = 743 Score = 63.2 bits (152), Expect = 6e-10 Identities = 35/141 (24%), Positives = 67/141 (47%), Gaps = 2/141 (1%) Frame = +3 Query: 183 RTLITGGEDQKVNLWAVGKPTAVLS--LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWD 356 R+LI GGE +++W + PT + L+ +L+ + + + G I +WD Sbjct: 516 RSLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWD 575 Query: 357 IEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRID 536 ++ +VR F GH + +D +G +G D ++ WD+R+ R + + + +I Sbjct: 576 LQNQTMVRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWDLREGRQLQQHD-FSSQIF 634 Query: 537 VLRFTPDGRWIVSGGADSSVK 599 L P+ W+ G S+V+ Sbjct: 635 SLGHCPNQDWLAVGMESSNVE 655 Score = 54.7 bits (130), Expect = 2e-07 Identities = 40/163 (24%), Positives = 75/163 (46%), Gaps = 7/163 (4%) Frame = +3 Query: 132 VAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEV 311 +AH +V CA +++ + TGG+ V +W VG+P A ++ L S ++ Sbjct: 454 LAHG-EVVCAVTISGSTQHVYTGGKGC-VKVWDVGQPGAKTPVAQLDCLNRDNYIRSCKL 511 Query: 312 M-----IGAGAASGTIKIWDIEEA--KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNM 470 + + G + T+ IWD+ ++ T C +L P S SD N+ Sbjct: 512 LPDGRSLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNI 571 Query: 471 KIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 +WD++ + + +QGHT + + G + +GG D++V+ Sbjct: 572 VVWDLQNQTMVRQFQGHTDGASCIDISDYGTRLWTGGLDNTVR 614
>COP1_PEA (P93471) Ubiquitin ligase protein COP1 (EC 6.3.2.-) (Constitutive| photomorphogenesis protein 1) Length = 672 Score = 62.8 bits (151), Expect = 7e-10 Identities = 40/169 (23%), Positives = 80/169 (47%), Gaps = 2/169 (1%) Frame = +3 Query: 96 MATKRAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTS 275 M T+++ L E+ H F + L++G +D KV +W + +VL++ + + Sbjct: 447 MTTRKS--LMEYEEHEKRAWSVDFSRTDPSMLVSGSDDCKVKVWCTNQEASVLNID-MKA 503 Query: 276 PVESLSFD-SSEVMIGAGAASGTIKIWDIEE-AKVVRTFTGHRSNCASLDSHPFGDFFAS 449 + + ++ S I G+A I +D+ ++ V FTGH+ S D AS Sbjct: 504 NICCVKYNPGSGNYIAVGSADHHIHYYDLRNISRPVHVFTGHKK-AVSYVKFLSNDELAS 562 Query: 450 GSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 S+D+ +++WD+++ + T++GH + + T +I G + V Sbjct: 563 ASTDSTLRLWDVKQNLPVRTFRGHANEKNFVGLTVRSEYIACGSETNEV 611 Score = 35.4 bits (80), Expect = 0.13 Identities = 28/117 (23%), Positives = 47/117 (40%), Gaps = 10/117 (8%) Frame = +3 Query: 279 VESLSFDSSEVMIGAGAASGTIKIWDIE---------EAKVVRTFTGHRSNCASLDSHPF 431 V S+ FD + + S IK++D VV T + +C S + + Sbjct: 371 VSSIEFDRDDDLFATAGVSRRIKVFDFSAVVNEPTDAHCPVVEMTTRSKLSCLSWNKYAK 430 Query: 432 GDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFT-PDGRWIVSGGADSSVK 599 AS + + +W M ++ + Y+ H R + F+ D +VSG D VK Sbjct: 431 NQ-IASSDYEGIVTVWTMTTRKSLMEYEEHEKRAWSVDFSRTDPSMLVSGSDDCKVK 486
>WDR3_HUMAN (Q9UNX4) WD-repeat protein 3| Length = 943 Score = 62.8 bits (151), Expect = 7e-10 Identities = 36/130 (27%), Positives = 62/130 (47%) Frame = +3 Query: 210 QKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFT 389 + V +W + K +L L GL V L + + G G+I+I+ + + TF Sbjct: 45 EHVFIWDLRKGEKILILQGLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFN 104 Query: 390 GHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWI 569 GH++ +L G ASGS DT++ +WD+ + ++ +GH I F + + Sbjct: 105 GHKAAITTLKYDQLGGRLASGSKDTDIIVWDVINESGLYRLKGHKDAITQALFLREKNLL 164 Query: 570 VSGGADSSVK 599 V+ G D+ VK Sbjct: 165 VTSGKDTMVK 174 Score = 60.1 bits (144), Expect = 5e-09 Identities = 40/151 (26%), Positives = 61/151 (40%) Frame = +3 Query: 147 DVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAG 326 DV C + + L D V ++ V LSL G PV + +I G Sbjct: 551 DVLCVSYSPN-QKLLAVSLLDCTVKIFYVDTLKFFLSLYGHKLPVICMDISHDGALIATG 609 Query: 327 AASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIH 506 +A +KIW ++ ++ H + L P F + D +K WD K I Sbjct: 610 SADRNVKIWGLDFGDCHKSLFAHDDSVMYLQFVPKSHLFFTAGKDHKIKQWDADKFEHIQ 669 Query: 507 TYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 T +GH I L +P G ++VS D S++ Sbjct: 670 TLEGHHQEIWCLAVSPSGDYVVSSSHDKSLR 700 Score = 58.5 bits (140), Expect = 1e-08 Identities = 35/119 (29%), Positives = 60/119 (50%) Frame = +3 Query: 243 TAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDS 422 T+ +++ G S V +LSF S + + AA+ +IKIW+ + +RT T + C+ Sbjct: 406 TSRITIGGHRSDVRTLSFSSDNIAV-LSAAADSIKIWNRSTLQCIRTMTCEYALCSFFV- 463 Query: 423 HPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 P G+ ++++D+ + T H G + + +PD R V+GGAD SVK Sbjct: 464 -PGDRQVVIGTKTGKLQLYDLASGNLLETIDAHDGALWSMSLSPDQRGFVTGGADKSVK 521 Score = 55.5 bits (132), Expect = 1e-07 Identities = 37/153 (24%), Positives = 61/153 (39%), Gaps = 14/153 (9%) Frame = +3 Query: 183 RTLITGGEDQKVNLWAVG--------------KPTAVLSLSGLTSPVESLSFDSSEVMIG 320 R +TGG D+ V W K T L L V +S+ ++ ++ Sbjct: 509 RGFVTGGADKSVKFWDFELVKDENSTQKRLSVKQTRTLQLD---EDVLCVSYSPNQKLLA 565 Query: 321 AGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRC 500 T+KI+ ++ K + GH+ +D G A+GS+D N+KIW + C Sbjct: 566 VSLLDCTVKIFYVDTLKFFLSLYGHKLPVICMDISHDGALIATGSADRNVKIWGLDFGDC 625 Query: 501 IHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 + H + L+F P + G D +K Sbjct: 626 HKSLFAHDDSVMYLQFVPKSHLFFTAGKDHKIK 658 Score = 48.5 bits (114), Expect = 1e-05 Identities = 26/137 (18%), Positives = 59/137 (43%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L G ED + ++++ ++ +G + + +L +D + +G+ I +WD+ Sbjct: 80 LAVGYEDGSIRIFSLLSGEGNVTFNGHKAAITTLKYDQLGGRLASGSKDTDIIVWDVINE 139 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 + GH+ + + DT +K WD+ + C T GH + L Sbjct: 140 SGLYRLKGHKDAITQALFLREKNLLVTSGKDTMVKWWDLDTQHCFKTMVGHRTEVWGLVL 199 Query: 549 TPDGRWIVSGGADSSVK 599 + + +++G +DS ++ Sbjct: 200 LSEEKRLITGASDSELR 216 Score = 48.1 bits (113), Expect = 2e-05 Identities = 26/105 (24%), Positives = 44/105 (41%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 + TG D+ V +W + SL V L F + IK WD ++ Sbjct: 606 IATGSADRNVKIWGLDFGDCHKSLFAHDDSVMYLQFVPKSHLFFTAGKDHKIKQWDADKF 665 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCI 503 + ++T GH L P GD+ S S D ++++W+ ++ I Sbjct: 666 EHIQTLEGHHQEIWCLAVSPSGDYVVSSSHDKSLRLWERTREPLI 710 Score = 35.0 bits (79), Expect = 0.17 Identities = 22/80 (27%), Positives = 34/80 (42%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 L H +T A F R L+T G+D V W + ++ G + V L Sbjct: 142 LYRLKGHKDAITQALF-LREKNLLVTSGKDTMVKWWDLDTQHCFKTMVGHRTEVWGLVLL 200 Query: 300 SSEVMIGAGAASGTIKIWDI 359 S E + GA+ +++WDI Sbjct: 201 SEEKRLITGASDSELRVWDI 220
>COPA_YEAST (P53622) Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP)| Length = 1201 Score = 62.8 bits (151), Expect = 7e-10 Identities = 27/106 (25%), Positives = 48/106 (45%) Frame = +3 Query: 282 ESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSD 461 + ++F S + S TI++WD ++ F H LD HP F S D Sbjct: 15 KGIAFHPSRPWVLVALFSSTIQLWDYRMGTLLHRFEDHEGPVRGLDFHPTQPIFVSAGDD 74 Query: 462 TNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 +K+W + +C++T GH + + F + WI+S D +++ Sbjct: 75 YTIKVWSLDTNKCLYTLTGHLDYVRTVFFHRELPWIISASDDQTIR 120 Score = 57.4 bits (137), Expect = 3e-08 Identities = 45/190 (23%), Positives = 70/190 (36%), Gaps = 30/190 (15%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 L F H V F T ++ G+D + +W++ + +L+G V ++ F Sbjct: 46 LHRFEDHEGPVRGLDFHP-TQPIFVSAGDDYTIKVWSLDTNKCLYTLTGHLDYVRTVFFH 104 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 I + + TI+IW+ + K + TGH HP D S S D ++IW Sbjct: 105 RELPWIISASDDQTIRIWNWQNRKEIACLTGHNHFVMCAQFHPTDDLIVSASLDETIRIW 164 Query: 480 DMRKKRCIHT------------------------------YQGHTGRIDVLRFTPDGRWI 569 D+ R H+ +GHT ++ F P I Sbjct: 165 DISGLRKRHSAPGTSSFEEQMSAQQNLLDGSLGDCVVKFILEGHTRGVNWASFHPTLPLI 224 Query: 570 VSGGADSSVK 599 VSG D VK Sbjct: 225 VSGSDDRQVK 234 Score = 55.5 bits (132), Expect = 1e-07 Identities = 31/128 (24%), Positives = 55/128 (42%) Frame = +3 Query: 216 VNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGH 395 + LW T + PV L F ++ + + TIK+W ++ K + T TGH Sbjct: 35 IQLWDYRMGTLLHRFEDHEGPVRGLDFHPTQPIFVSAGDDYTIKVWSLDTNKCLYTLTGH 94 Query: 396 RSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVS 575 ++ H + S S D ++IW+ + ++ I GH + +F P IVS Sbjct: 95 LDYVRTVFFHRELPWIISASDDQTIRIWNWQNRKEIACLTGHNHFVMCAQFHPTDDLIVS 154 Query: 576 GGADSSVK 599 D +++ Sbjct: 155 ASLDETIR 162 Score = 44.7 bits (104), Expect = 2e-04 Identities = 26/101 (25%), Positives = 46/101 (45%), Gaps = 2/101 (1%) Frame = +3 Query: 258 LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKV--VRTFTGHRSNCASLDSHPF 431 L G T V SF + +I +G+ +K+W + K V T GH +N S+ HP Sbjct: 205 LEGHTRGVNWASFHPTLPLIVSGSDDRQVKLWRMSATKAWEVDTCRGHTNNVDSVIFHPH 264 Query: 432 GDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTP 554 + S D +++WD+ K+ + ++ R ++ P Sbjct: 265 QNLIISVGEDKTLRVWDLDKRTPVKQFKRENDRFWLIAAHP 305 Score = 43.9 bits (102), Expect = 4e-04 Identities = 28/122 (22%), Positives = 61/122 (50%), Gaps = 2/122 (1%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTA--VLSLSGLTSPVESLSFDSSEV 311 H V A F T +++G +D++V LW + A V + G T+ V+S+ F + Sbjct: 208 HTRGVNWASFHP-TLPLIVSGSDDRQVKLWRMSATKAWEVDTCRGHTNNVDSVIFHPHQN 266 Query: 312 MIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRK 491 +I + T+++WD+++ V+ F + +HP + F + + D+ + ++ + + Sbjct: 267 LIISVGEDKTLRVWDLDKRTPVKQFKRENDRFWLIAAHPHINLFGA-AHDSGIMVFKLDR 325 Query: 492 KR 497 +R Sbjct: 326 ER 327 Score = 36.2 bits (82), Expect = 0.074 Identities = 18/77 (23%), Positives = 33/77 (42%) Frame = +3 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 K++ F + + HP + + +++WD R +H ++ H G + L F Sbjct: 2 KMLTKFESKSTRAKGIAFHPSRPWVLVALFSSTIQLWDYRMGTLLHRFEDHEGPVRGLDF 61 Query: 549 TPDGRWIVSGGADSSVK 599 P VS G D ++K Sbjct: 62 HPTQPIFVSAGDDYTIK 78
>TLE2_BRARE (O13166) Groucho 2 protein| Length = 761 Score = 62.8 bits (151), Expect = 7e-10 Identities = 36/141 (25%), Positives = 63/141 (44%), Gaps = 2/141 (1%) Frame = +3 Query: 183 RTLITGGEDQKVNLWAVGKPTAVLS--LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWD 356 RTLI GGE + +W + T + L+ +L+ + + + G I +WD Sbjct: 534 RTLIVGGEASTLTIWDLASQTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWD 593 Query: 357 IEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRID 536 + +VR F GH + +D G +G D ++ WD+R+ R + + +I Sbjct: 594 LHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHD-FASQIF 652 Query: 537 VLRFTPDGRWIVSGGADSSVK 599 L + P G W+ G S+V+ Sbjct: 653 SLGYCPTGEWLAVGMESSNVE 673 Score = 57.8 bits (138), Expect = 2e-08 Identities = 43/166 (25%), Positives = 70/166 (42%), Gaps = 15/166 (9%) Frame = +3 Query: 147 DVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLS----------- 293 +V CA +R + TGG+ V +W + +P G SPV L Sbjct: 476 EVVCAVTISNPTRHVYTGGKGC-VKIWDISQP-------GSKSPVSQLDCLNRDNYIRSC 527 Query: 294 --FDSSEVMIGAGAASGTIKIWDI--EEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSD 461 +I G AS T+ IWD+ + ++ T C +L P S SD Sbjct: 528 KLLPDGRTLIVGGEAS-TLTIWDLASQTPRIKAELTSSAPACYALAISPDAKVCFSCCSD 586 Query: 462 TNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 N+ +WD+ + + +QGHT + + DG + +GG D++V+ Sbjct: 587 GNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVR 632
>GBB_ORYSA (Q40687) Guanine nucleotide-binding protein beta subunit| Length = 380 Score = 62.4 bits (150), Expect = 1e-09 Identities = 48/161 (29%), Positives = 75/161 (46%), Gaps = 14/161 (8%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAV--GKPTAVLS---LSGLTSPVESLSFDS 302 H V+ ++ LIT DQ LW V G+ ++ SG T+ V SLS +S Sbjct: 156 HKGYVSSCQYVPDQETRLITSSGDQTCVLWDVTTGQRISIFGGEFPSGHTADVLSLSINS 215 Query: 303 SEV-MIGAGAASGTIKIWDIEEA-KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 S M +G+ T+++WDI A + VRT+ GH + S+ P G F +GS D ++ Sbjct: 216 SNSNMFVSGSCDATVRLWDIRIASRAVRTYHGHEGDINSVKFFPDGQRFGTGSDDGTCRL 275 Query: 477 WDMRKKRCIHTYQGHTGRID-------VLRFTPDGRWIVSG 578 +D+R + Y R D + F+ GR + +G Sbjct: 276 FDVRTGHQLQVYSREPDRNDNELPTVTSIAFSISGRLLFAG 316 Score = 56.2 bits (134), Expect = 7e-08 Identities = 34/122 (27%), Positives = 59/122 (48%), Gaps = 8/122 (6%) Frame = +3 Query: 258 LSGLTSPVESLSF-DSSEVMIGAGAASGTIKIWDIEEAKVVRTF-----TGHRSNCASLD 419 L+G V S + E + + T +WD+ + + F +GH ++ SL Sbjct: 153 LTGHKGYVSSCQYVPDQETRLITSSGDQTCVLWDVTTGQRISIFGGEFPSGHTADVLSLS 212 Query: 420 SHPFG-DFFASGSSDTNMKIWDMR-KKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSS 593 + + F SGS D +++WD+R R + TY GH G I+ ++F PDG+ +G D + Sbjct: 213 INSSNSNMFVSGSCDATVRLWDIRIASRAVRTYHGHEGDINSVKFFPDGQRFGTGSDDGT 272 Query: 594 VK 599 + Sbjct: 273 CR 274 Score = 42.0 bits (97), Expect = 0.001 Identities = 21/72 (29%), Positives = 33/72 (45%) Frame = +3 Query: 378 RTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPD 557 RT GH SLD P ++ S S D + +W+ + H + H + F P+ Sbjct: 60 RTLQGHSGKVYSLDWTPEKNWIVSASQDGRLIVWNALTSQKTHAIKLHCPWVMTCAFAPN 119 Query: 558 GRWIVSGGADSS 593 G+ + GG DS+ Sbjct: 120 GQSVACGGLDSA 131 Score = 38.1 bits (87), Expect = 0.020 Identities = 32/123 (26%), Positives = 45/123 (36%), Gaps = 4/123 (3%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 Q F + D TC F RT L + N V S++F Sbjct: 262 QRFGTGSDDGTCRLFDVRTGHQLQVYSREPDRN-------------DNELPTVTSIAFSI 308 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTF----TGHRSNCASLDSHPFGDFFASGSSDTNM 470 S ++ AG ++G +WD A+VV H + L G +GS D N+ Sbjct: 309 SGRLLFAGYSNGDCYVWDTLLAEVVLNLGNLQNSHEGRISCLGLSSDGSALCTGSWDKNL 368 Query: 471 KIW 479 KIW Sbjct: 369 KIW 371 Score = 35.8 bits (81), Expect = 0.097 Identities = 14/30 (46%), Positives = 19/30 (63%) Frame = +3 Query: 498 CIHTYQGHTGRIDVLRFTPDGRWIVSGGAD 587 C T QGH+G++ L +TP+ WIVS D Sbjct: 58 CCRTLQGHSGKVYSLDWTPEKNWIVSASQD 87
>PRP4_ARATH (O22212) U4/U6 small nuclear ribonucleoprotein PRP4-like protein| Length = 554 Score = 62.4 bits (150), Expect = 1e-09 Identities = 35/160 (21%), Positives = 67/160 (41%), Gaps = 1/160 (0%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 LQ F H + F + + L T D+ LW + +L G + V ++F Sbjct: 332 LQTFEGHLDRLARVAFHP-SGKYLGTTSYDKTWRLWDINTGAELLLQEGHSRSVYGIAFQ 390 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 + + ++WD+ + + F GH S++ P G ASG D +IW Sbjct: 391 QDGALAASCGLDSLARVWDLRTGRSILVFQGHIKPVFSVNFSPNGYHLASGGEDNQCRIW 450 Query: 480 DMRKKRCIHTYQGHTGRIDVLRFTP-DGRWIVSGGADSSV 596 D+R ++ ++ H + +++ P +G ++ + D V Sbjct: 451 DLRMRKSLYIIPAHANLVSQVKYEPQEGYFLATASYDMKV 490 Score = 58.9 bits (141), Expect = 1e-08 Identities = 35/137 (25%), Positives = 60/137 (43%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L T D+ LW T + + G + ++F S +G + T ++WDI Sbjct: 313 LATASADRTAKLWKTDG-TLLQTFEGHLDRLARVAFHPSGKYLGTTSYDKTWRLWDINTG 371 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 + GH + + G AS D+ ++WD+R R I +QGH + + F Sbjct: 372 AELLLQEGHSRSVYGIAFQQDGALAASCGLDSLARVWDLRTGRSILVFQGHIKPVFSVNF 431 Query: 549 TPDGRWIVSGGADSSVK 599 +P+G + SGG D+ + Sbjct: 432 SPNGYHLASGGEDNQCR 448 Score = 54.3 bits (129), Expect = 3e-07 Identities = 32/134 (23%), Positives = 56/134 (41%), Gaps = 1/134 (0%) Frame = +3 Query: 201 GEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVR 380 G D +W + ++L G PV S++F + + +G +IWD+ K + Sbjct: 400 GLDSLARVWDLRTGRSILVFQGHIKPVFSVNFSPNGYHLASGGEDNQCRIWDLRMRKSLY 459 Query: 381 TFTGHRSNCASLDSHPF-GDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPD 557 H + + + P G F A+ S D + IW R + + GH ++ L T D Sbjct: 460 IIPAHANLVSQVKYEPQEGYFLATASYDMKVNIWSGRDFSLVKSLAGHESKVASLDITAD 519 Query: 558 GRWIVSGGADSSVK 599 I + D ++K Sbjct: 520 SSCIATVSHDRTIK 533 Score = 43.9 bits (102), Expect = 4e-04 Identities = 23/98 (23%), Positives = 44/98 (44%), Gaps = 1/98 (1%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSE-VMIGAGAASGTIKIWDIEE 365 L +GGED + +W + ++ + + V + ++ E + + + IW + Sbjct: 438 LASGGEDNQCRIWDLRMRKSLYIIPAHANLVSQVKYEPQEGYFLATASYDMKVNIWSGRD 497 Query: 366 AKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 +V++ GH S ASLD A+ S D +K+W Sbjct: 498 FSLVKSLAGHESKVASLDITADSSCIATVSHDRTIKLW 535 Score = 41.6 bits (96), Expect = 0.002 Identities = 25/73 (34%), Positives = 36/73 (49%) Frame = +3 Query: 135 AHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVM 314 AHA+ V+ K+ + L T D KVN+W+ + V SL+G S V SL + Sbjct: 463 AHANLVSQVKYEPQEGYFLATASYDMKVNIWSGRDFSLVKSLAGHESKVASLDITADSSC 522 Query: 315 IGAGAASGTIKIW 353 I + TIK+W Sbjct: 523 IATVSHDRTIKLW 535
>UTP15_HUMAN (Q8TED0) U3 small nucleolar RNA-associated protein 15 homolog| Length = 518 Score = 62.4 bits (150), Expect = 1e-09 Identities = 43/146 (29%), Positives = 71/146 (48%), Gaps = 4/146 (2%) Frame = +3 Query: 156 CAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAAS 335 CA F ++ R L+ G ED V L+ + + G T V ++ + + + +GA Sbjct: 85 CATF-RQDGRLLVAGSEDGGVQLFDISGRAPLRQFEGHTKAVHTVDSTADKYHVVSGADD 143 Query: 336 GTIKIWDIEEAKVVRTFTGH----RSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCI 503 T+K+WDI +K + TF H R CAS +P D F +GS D +K++D R + Sbjct: 144 YTVKLWDIPNSKEILTFKEHSDYVRCGCAS-KLNP--DLFITGSYDHTVKMFDARTSESV 200 Query: 504 HTYQGHTGRIDVLRFTPDGRWIVSGG 581 + + H ++ + P G +VS G Sbjct: 201 LSVE-HGQPVESVLLFPSGGLLVSAG 225 Score = 46.2 bits (108), Expect = 7e-05 Identities = 34/130 (26%), Positives = 57/130 (43%), Gaps = 2/130 (1%) Frame = +3 Query: 129 FVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVES-LSFDSS 305 F H+ V C K ITG D V ++ +VLS+ PVES L F S Sbjct: 160 FKEHSDYVRCGCASKLNPDLFITGSYDHTVKMFDARTSESVLSVEH-GQPVESVLLFPSG 218 Query: 306 EVMIGAGAASGTIKIWD-IEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 +++ AG +K+WD ++ +++ + H L G SGS D +K++ Sbjct: 219 GLLVSAGGR--YVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYS 276 Query: 483 MRKKRCIHTY 512 + +H++ Sbjct: 277 TTSYKVVHSF 286 Score = 40.8 bits (94), Expect = 0.003 Identities = 23/93 (24%), Positives = 43/93 (46%) Frame = +3 Query: 321 AGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRC 500 A AS I I+ + ++TF+ + G +GS D ++++D+ + Sbjct: 55 AVTASSRIHIYGRYSQEPIKTFSRFKDTAYCATFRQDGRLLVAGSEDGGVQLFDISGRAP 114 Query: 501 IHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 + ++GHT + + T D +VSG D +VK Sbjct: 115 LRQFEGHTKAVHTVDSTADKYHVVSGADDYTVK 147
>WS17_SCHMA (Q26544) WD-repeat protein SL1-17| Length = 301 Score = 62.4 bits (150), Expect = 1e-09 Identities = 32/118 (27%), Positives = 61/118 (51%), Gaps = 1/118 (0%) Frame = +3 Query: 246 AVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAK-VVRTFTGHRSNCASLDS 422 +V L G +PV S+SF ++ + + IK++D+ + + V+ + GH+ S+D Sbjct: 178 SVQFLDGHATPVRSVSFSPDGRLLASASDDKQIKVFDVRDGRLVIPSLNGHKGWVVSVDF 237 Query: 423 HPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 + S+D +++IWD+ K H + H ++ R++P G I+S G D S+ Sbjct: 238 ASDNRHLVTASTDCSVRIWDLASKEEKHCFNTHEDQVWCARYSPQGNNIISVGDDRSI 295 Score = 57.0 bits (136), Expect = 4e-08 Identities = 43/141 (30%), Positives = 64/141 (45%), Gaps = 1/141 (0%) Frame = +3 Query: 180 SRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDI 359 SR L TG VN+ V S+ V L++ S + AG +G + I D+ Sbjct: 115 SRFLATGSHTGCVNMINVQTAQKEGSIQLEGKFVYXLAYISDGSKLAAGTINGLVSICDL 174 Query: 360 EEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKR-CIHTYQGHTGRID 536 E V + GH + S+ P G AS S D +K++D+R R I + GH G + Sbjct: 175 ETGSV-QFLDGHATPVRSVSFSPDGRLLASASDDKQIKVFDVRDGRLVIPSLNGHKGWVV 233 Query: 537 VLRFTPDGRWIVSGGADSSVK 599 + F D R +V+ D SV+ Sbjct: 234 SVDFASDNRHLVTASTDCSVR 254 Score = 51.2 bits (121), Expect = 2e-06 Identities = 24/76 (31%), Positives = 37/76 (48%) Frame = +3 Query: 351 WDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGR 530 W + K + F GHR S+D + G AS S D+ + +WD+ R TY G Sbjct: 46 WTNSQLKCLYQFEGHRLGVISVDINSTGTLAASSSLDSQILLWDLETGRLTKTYDGDPAD 105 Query: 531 IDVLRFTPDGRWIVSG 578 + F+PD R++ +G Sbjct: 106 TWTIAFSPDSRFLATG 121
>WSB2_HUMAN (Q9NYS7) WD repeat and SOCS box-containing protein 2 (WSB-2) (CS| box-containing WD protein) Length = 404 Score = 62.0 bits (149), Expect = 1e-09 Identities = 38/138 (27%), Positives = 64/138 (46%), Gaps = 2/138 (1%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASG-TIKIWDIEE 365 L TG D ++ +W V +L+LSG V LSF S +I A+ T++IWD+ + Sbjct: 126 LATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNK 185 Query: 366 -AKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVL 542 K ++ +GH P S + + ++ +W MR I +GH + Sbjct: 186 HGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSC 245 Query: 543 RFTPDGRWIVSGGADSSV 596 F+PD +V+ D++V Sbjct: 246 DFSPDSALLVTASYDTNV 263 Score = 49.3 bits (116), Expect = 8e-06 Identities = 28/102 (27%), Positives = 46/102 (45%), Gaps = 2/102 (1%) Frame = +3 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGD-FFASGSSDTNMK 473 D S +++ G G IKIW+++ ++ +GH+ L P G S S D ++ Sbjct: 120 DVSCLVLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLR 179 Query: 474 IWDMRKK-RCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 IWD+ K + I GH + +PD + S + SV Sbjct: 180 IWDLNKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSV 221 Score = 48.9 bits (115), Expect = 1e-05 Identities = 37/163 (22%), Positives = 66/163 (40%), Gaps = 13/163 (7%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLS-LSGLTSPVESLSFDSSEVM 314 H V F S L++ D+ + +W + K + LSG V S M Sbjct: 152 HQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNKHGKQIQVLSGHLQWVYCCSISPDCSM 211 Query: 315 IGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDM--- 485 + + A ++ +W + ++R GH+S+ S D P + S DTN+ +WD Sbjct: 212 LCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCDFSPDSALLVTASYDTNVIMWDPYTG 271 Query: 486 RKKRCIHTYQ---------GHTGRIDVLRFTPDGRWIVSGGAD 587 + R +H Q H + + F+P+G ++ + D Sbjct: 272 ERLRSLHHTQVDPAMDDSDVHISSLRSVCFSPEGLYLATVADD 314
>TIPD_DICDI (O15736) Protein tipD| Length = 612 Score = 62.0 bits (149), Expect = 1e-09 Identities = 49/178 (27%), Positives = 78/178 (43%), Gaps = 5/178 (2%) Frame = +3 Query: 81 LLPSRMATKRAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSL 260 +LPS+ A KR + H S++ C F L TGG D+ V +W V +L Sbjct: 311 MLPSK-AKKR------WTGHNSEIYCMAFNS-IGNLLATGGGDKCVKVWDVISGQQKSTL 362 Query: 261 SGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDF 440 G + + S+SF ++ I + + ++W+ E + T TGH + G F Sbjct: 363 LGASQSIVSVSFSPNDESILGTSNDNSARLWNTELGRSRHTLTGHIGKVYT------GKF 416 Query: 441 FAS-----GSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 S GS D +K+WD++K C T + D++ G + SG D SV+ Sbjct: 417 INSNRVVTGSHDRTIKLWDLQKGYCTRTIFCFSSCNDLVILGGSGTHLASGHVDHSVR 474 Score = 49.7 bits (117), Expect = 6e-06 Identities = 37/159 (23%), Positives = 68/159 (42%), Gaps = 6/159 (3%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMI 317 H V KF S ++TG D+ + LW + K ++ +S + + S + Sbjct: 407 HIGKVYTGKF--INSNRVVTGSHDRTIKLWDLQKGYCTRTIFCFSSCNDLVILGGSGTHL 464 Query: 318 GAGAASGTIKIWDIEEAKVVRTFTG-HRSNCASLDSHPFG-DFFASGSSDTNMKIWDMRK 491 +G +++ WD + + + H S+ + P + + S D +KI D+R Sbjct: 465 ASGHVDHSVRFWDSNAGEPTQVLSSIHEGQITSITNSPTNTNQILTNSRDHTLKIIDIRT 524 Query: 492 KRCIHTYQGHTGRIDV----LRFTPDGRWIVSGGADSSV 596 I T++ R + ++PDGR+I SG D S+ Sbjct: 525 FDTIRTFKDPEYRNGLNWTKASWSPDGRYIASGSIDGSI 563 Score = 39.7 bits (91), Expect = 0.007 Identities = 31/106 (29%), Positives = 49/106 (46%), Gaps = 8/106 (7%) Frame = +3 Query: 189 LITGGEDQKVNLWA--VGKPTAVLSL--SGLTSPVESLSFDSSEVMIGAGAASGTIKIWD 356 L +G D V W G+PT VLS G + + + ++++++ + T+KI D Sbjct: 464 LASGHVDHSVRFWDSNAGEPTQVLSSIHEGQITSITNSPTNTNQIL--TNSRDHTLKIID 521 Query: 357 IEEAKVVRTFTG----HRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 I +RTF + N P G + ASGS D ++ IWD Sbjct: 522 IRTFDTIRTFKDPEYRNGLNWTKASWSPDGRYIASGSIDGSICIWD 567 Score = 39.3 bits (90), Expect = 0.009 Identities = 24/101 (23%), Positives = 46/101 (45%) Frame = +3 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 D+++V I G + +K + +TGH S + + G+ A+G D +K+ Sbjct: 291 DANDVPIPIVLERGVFSSEAMLPSKAKKRWTGHNSEIYCMAFNSIGNLLATGGGDKCVKV 350 Query: 477 WDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 WD+ + T G + I + F+P+ I+ D+S + Sbjct: 351 WDVISGQQKSTLLGASQSIVSVSFSPNDESILGTSNDNSAR 391
>PRP17_HUMAN (O60508) Pre-mRNA-splicing factor PRP17 (hPRP17) (Cell division| cycle 40 homolog) (EH-binding protein 3) (Ehb3) Length = 579 Score = 61.6 bits (148), Expect = 2e-09 Identities = 40/179 (22%), Positives = 77/179 (43%), Gaps = 7/179 (3%) Frame = +3 Query: 84 LPSRMATKRAY----KLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAV-GKPTA 248 L S M ++ Y ++ + H V+ + + L++ D K+ LW V G+ Sbjct: 265 LRSTMPPEKCYLPKKQIHVWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIKLWEVYGERRC 324 Query: 249 VLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHR-SNCASLD-S 422 + + G + V + F+++ + A +K+WD E + + FT + C + Sbjct: 325 LRTFIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWDTETGQCISRFTNRKVPYCVKFNPD 384 Query: 423 HPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 + F +G SD + WD+R + Y H G ++ + F + R VS D S++ Sbjct: 385 EDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDENRRFVSTSDDKSLR 443
>CSTF1_RAT (Q5BJQ6) Cleavage stimulation factor, 50 kDa subunit (CSTF 50 kDa| subunit) (CF-1 50 kDa subunit) (CstF-50) Length = 431 Score = 61.6 bits (148), Expect = 2e-09 Identities = 44/161 (27%), Positives = 76/161 (47%), Gaps = 7/161 (4%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSP--VESLSFDSSEV 311 H +VTC F T + L +G D + L+ KP+A + + + S+SF S Sbjct: 172 HVDEVTCLAFHP-TEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGD 230 Query: 312 MIGAGAASGTIKIWDIEEAKVVRTFTG---HRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 I G T++++DI + + H S++ +P + + +GS D +K+WD Sbjct: 231 FILVGTQHPTLRLYDINTFQCFVSCNPQDQHTDAICSVNYNPSANMYVTGSKDGCIKLWD 290 Query: 483 MRKKRCIHTYQ-GHTG-RIDVLRFTPDGRWIVSGGADSSVK 599 RCI T++ H G + F+ + ++I+S G DS K Sbjct: 291 GVSNRCITTFEKAHDGAEVCSAIFSKNSKYILSSGKDSVAK 331 Score = 36.2 bits (82), Expect = 0.074 Identities = 31/127 (24%), Positives = 48/127 (37%), Gaps = 26/127 (20%) Frame = +3 Query: 276 PVESLSFDSSEVMIGAGAASGTIKIWD-----------------------IEEAKVVRTF 386 P ++ +I G+A +IKI D +E V+RT Sbjct: 110 PCRVATYSRDGQLIATGSADASIKILDTERMLAKSAMPIEVMMNETAQQNMENHPVIRTL 169 Query: 387 TGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLR---FTPD 557 H L HP ASGS D +K++D K ++ + ++LR F P Sbjct: 170 YDHVDEVTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFK-YIQEAEMLRSISFHPS 228 Query: 558 GRWIVSG 578 G +I+ G Sbjct: 229 GDFILVG 235
>CSTF1_MOUSE (Q99LC2) Cleavage stimulation factor, 50 kDa subunit (CSTF 50 kDa| subunit) (CF-1 50 kDa subunit) (CstF-50) Length = 431 Score = 61.6 bits (148), Expect = 2e-09 Identities = 44/161 (27%), Positives = 76/161 (47%), Gaps = 7/161 (4%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSP--VESLSFDSSEV 311 H +VTC F T + L +G D + L+ KP+A + + + S+SF S Sbjct: 172 HVDEVTCLAFHP-TEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGD 230 Query: 312 MIGAGAASGTIKIWDIEEAKVVRTFTG---HRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 I G T++++DI + + H S++ +P + + +GS D +K+WD Sbjct: 231 FILVGTQHPTLRLYDINTFQCFVSCNPQDQHTDAICSVNYNPSANMYVTGSKDGCIKLWD 290 Query: 483 MRKKRCIHTYQ-GHTG-RIDVLRFTPDGRWIVSGGADSSVK 599 RCI T++ H G + F+ + ++I+S G DS K Sbjct: 291 GVSNRCITTFEKAHDGAEVCSAIFSKNSKYILSSGKDSVAK 331 Score = 36.2 bits (82), Expect = 0.074 Identities = 31/127 (24%), Positives = 48/127 (37%), Gaps = 26/127 (20%) Frame = +3 Query: 276 PVESLSFDSSEVMIGAGAASGTIKIWD-----------------------IEEAKVVRTF 386 P ++ +I G+A +IKI D +E V+RT Sbjct: 110 PCRVATYSRDGQLIATGSADASIKILDTERMLAKSAMPIEVMMNETAQQNMENHPVIRTL 169 Query: 387 TGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLR---FTPD 557 H L HP ASGS D +K++D K ++ + ++LR F P Sbjct: 170 YDHVDEVTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFK-YIQEAEMLRSISFHPS 228 Query: 558 GRWIVSG 578 G +I+ G Sbjct: 229 GDFILVG 235
>PRP17_YEAST (P40968) Pre-mRNA-splicing factor PRP17 (Cell division control| protein 40) Length = 455 Score = 61.6 bits (148), Expect = 2e-09 Identities = 42/165 (25%), Positives = 72/165 (43%), Gaps = 5/165 (3%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVL-SLSGLTSPVESLSF 296 ++ + H T KF +T +++GG D + +W L G P+++L F Sbjct: 155 IRNYPGHPEGTTALKFLPKTGHLILSGGNDHTIKIWDFYHDYECLRDFQGHNKPIKALRF 214 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDF-FASGSSDTNMK 473 + + ++KIWD E K V+T S A ++S P F G S++ + Sbjct: 215 TEDCQSFLSSSFDRSVKIWDTETGK-VKTRLHLNSTPADVESRPTNPHEFIVGLSNSKIL 273 Query: 474 IWDMR---KKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 +D R + + TY H I L++ PDG +S D +V+ Sbjct: 274 HYDDRVSENQGLVQTYDHHLSSILALKYFPDGSKFISSSEDKTVR 318 Score = 52.8 bits (125), Expect = 8e-07 Identities = 30/79 (37%), Positives = 39/79 (49%), Gaps = 2/79 (2%) Frame = +3 Query: 369 KVVRTFTGHRSNCASLDSHP-FGDFFASGSSDTNMKIWDM-RKKRCIHTYQGHTGRIDVL 542 KV+R + GH +L P G SG +D +KIWD C+ +QGH I L Sbjct: 153 KVIRNYPGHPEGTTALKFLPKTGHLILSGGNDHTIKIWDFYHDYECLRDFQGHNKPIKAL 212 Query: 543 RFTPDGRWIVSGGADSSVK 599 RFT D + +S D SVK Sbjct: 213 RFTEDCQSFLSSSFDRSVK 231 Score = 29.6 bits (65), Expect = 6.9 Identities = 15/37 (40%), Positives = 20/37 (54%), Gaps = 1/37 (2%) Frame = +3 Query: 492 KRCIHTYQGHTGRIDVLRFTP-DGRWIVSGGADSSVK 599 K+ I Y GH L+F P G I+SGG D ++K Sbjct: 152 KKVIRNYPGHPEGTTALKFLPKTGHLILSGGNDHTIK 188
>YJL2_YEAST (P47025) Hypothetical 80.0 kDa Trp-Asp repeats-containing protein in| ASF1-CCT7 intergenic region Length = 714 Score = 61.2 bits (147), Expect = 2e-09 Identities = 50/202 (24%), Positives = 84/202 (41%), Gaps = 41/202 (20%) Frame = +3 Query: 117 KLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVG-------------KPT---- 245 K+ E H + + C + R TL+TGG D + LW + PT Sbjct: 433 KIGELAGHLATINCMQIN-RDYGTLVTGGRDAALKLWNLNLAQQLYQETQNLTSPTNHID 491 Query: 246 --AVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLD 419 V + T V +LS D S ++ +G+ TI+ WD+ K ++T +N + Sbjct: 492 SPCVHTFEAHTDEVTALSLDPSFLV--SGSQDRTIRQWDLRSGKCLQTIDLSFANVLTTS 549 Query: 420 SH----------------------PFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRI 533 ++ F A+G+ D +++WD+R + I T +GHT I Sbjct: 550 TNVDLSKSTLLTQRNERPSIGALQSFDAALATGTKDGVVRLWDLRSGKVIRTLKGHTDAI 609 Query: 534 DVLRFTPDGRWIVSGGADSSVK 599 L+F D +V+G D +V+ Sbjct: 610 TSLKF--DSACLVTGSYDRTVR 629 Score = 50.4 bits (119), Expect = 4e-06 Identities = 30/143 (20%), Positives = 52/143 (36%), Gaps = 19/143 (13%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMI 317 H +TC F G D V +W + K + L+G + + + + + Sbjct: 397 HDDFLTCLDFDAPFGTLCTAGYLDHTVKIWDLSKQNKIGELAGHLATINCMQINRDYGTL 456 Query: 318 GAGAASGTIKIWDIE-------------------EAKVVRTFTGHRSNCASLDSHPFGDF 440 G +K+W++ ++ V TF H +L P F Sbjct: 457 VTGGRDAALKLWNLNLAQQLYQETQNLTSPTNHIDSPCVHTFEAHTDEVTALSLDP--SF 514 Query: 441 FASGSSDTNMKIWDMRKKRCIHT 509 SGS D ++ WD+R +C+ T Sbjct: 515 LVSGSQDRTIRQWDLRSGKCLQT 537 Score = 49.3 bits (116), Expect = 8e-06 Identities = 35/142 (24%), Positives = 55/142 (38%), Gaps = 22/142 (15%) Frame = +3 Query: 129 FVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAV--GKPTAVLSLSGLTSPVESLSFDS 302 F AH +VT L++G +D+ + W + GK + LS S + D Sbjct: 498 FEAHTDEVTALSLDPSF---LVSGSQDRTIRQWDLRSGKCLQTIDLSFANVLTTSTNVDL 554 Query: 303 S--------------------EVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDS 422 S + + G G +++WD+ KV+RT GH SL Sbjct: 555 SKSTLLTQRNERPSIGALQSFDAALATGTKDGVVRLWDLRSGKVIRTLKGHTDAITSLKF 614 Query: 423 HPFGDFFASGSSDTNMKIWDMR 488 +GS D ++IWD+R Sbjct: 615 D--SACLVTGSYDRTVRIWDLR 634 Score = 46.2 bits (108), Expect = 7e-05 Identities = 30/126 (23%), Positives = 55/126 (43%), Gaps = 22/126 (17%) Frame = +3 Query: 288 LSFDSS-EVMIGAGAASGTIKIWDIEEAKVVRTFTGHRS--NCASLDSHPFGDFFASGSS 458 L FD+ + AG T+KIWD+ + + GH + NC + + +G +G Sbjct: 404 LDFDAPFGTLCTAGYLDHTVKIWDLSKQNKIGELAGHLATINCMQI-NRDYGT-LVTGGR 461 Query: 459 DTNMKIWDMRKKR-------------------CIHTYQGHTGRIDVLRFTPDGRWIVSGG 581 D +K+W++ + C+HT++ HT + L P ++VSG Sbjct: 462 DAALKLWNLNLAQQLYQETQNLTSPTNHIDSPCVHTFEAHTDEVTALSLDPS--FLVSGS 519 Query: 582 ADSSVK 599 D +++ Sbjct: 520 QDRTIR 525 Score = 44.7 bits (104), Expect = 2e-04 Identities = 22/65 (33%), Positives = 35/65 (53%) Frame = +3 Query: 405 CASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGA 584 C D+ PFG +G D +KIWD+ K+ I GH I+ ++ D +V+GG Sbjct: 403 CLDFDA-PFGTLCTAGYLDHTVKIWDLSKQNKIGELAGHLATINCMQINRDYGTLVTGGR 461 Query: 585 DSSVK 599 D+++K Sbjct: 462 DAALK 466
>RFWD2_HUMAN (Q8NHY2) Ring finger and WD repeat domain protein 2 (EC 6.3.2.-)| (Ubiquitin-protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1) Length = 731 Score = 61.2 bits (147), Expect = 2e-09 Identities = 35/145 (24%), Positives = 65/145 (44%), Gaps = 1/145 (0%) Frame = +3 Query: 165 FGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTI 344 F + L +G +D KV LW+ +V S+ + SS + G A + Sbjct: 521 FNLMDPKLLASGSDDAKVKLWSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCV 580 Query: 345 KIWDIEEAKV-VRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGH 521 +D+ K + F GHR S G+ S S+D+ +K+W++ K C+ +++GH Sbjct: 581 HYYDLRNTKQPIMVFKGHRK-AVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGH 639 Query: 522 TGRIDVLRFTPDGRWIVSGGADSSV 596 + + +G +I G ++S+ Sbjct: 640 INEKNFVGLASNGDYIACGSENNSL 664 Score = 36.6 bits (83), Expect = 0.057 Identities = 25/111 (22%), Positives = 50/111 (45%), Gaps = 3/111 (2%) Frame = +3 Query: 273 SPVESLSFDS-SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFG-DFFA 446 S + +S+ S + ++ + GT+ +WD + + + H C S+D + A Sbjct: 471 SKISCISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLA 530 Query: 447 SGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRW-IVSGGADSSV 596 SGS D +K+W + + + + ++F+P R+ + G AD V Sbjct: 531 SGSDDAKVKLWSTNLDNSVASIEA-KANVCCVKFSPSSRYHLAFGCADHCV 580 Score = 34.3 bits (77), Expect = 0.28 Identities = 21/86 (24%), Positives = 40/86 (46%) Frame = +3 Query: 129 FVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSE 308 F H V+ AKF + +++ D ++ LW VGKP + S G + + S+ Sbjct: 595 FKGHRKAVSYAKFV--SGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNG 652 Query: 309 VMIGAGAASGTIKIWDIEEAKVVRTF 386 I G+ + ++ ++ +K + TF Sbjct: 653 DYIACGSENNSLYLYYKGLSKTLLTF 678
>RFWD2_MOUSE (Q9R1A8) Ring finger and WD repeat domain protein 2 (EC 6.3.2.-)| (Ubiquitin-protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1) Length = 733 Score = 61.2 bits (147), Expect = 2e-09 Identities = 35/145 (24%), Positives = 65/145 (44%), Gaps = 1/145 (0%) Frame = +3 Query: 165 FGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTI 344 F + L +G +D KV LW+ +V S+ + SS + G A + Sbjct: 523 FNLMDPKLLASGSDDAKVKLWSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCV 582 Query: 345 KIWDIEEAKV-VRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGH 521 +D+ K + F GHR S G+ S S+D+ +K+W++ K C+ +++GH Sbjct: 583 HYYDLRNTKQPIMVFKGHRK-AVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGH 641 Query: 522 TGRIDVLRFTPDGRWIVSGGADSSV 596 + + +G +I G ++S+ Sbjct: 642 INEKNFVGLASNGDYIACGSENNSL 666 Score = 36.6 bits (83), Expect = 0.057 Identities = 25/111 (22%), Positives = 50/111 (45%), Gaps = 3/111 (2%) Frame = +3 Query: 273 SPVESLSFDS-SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFG-DFFA 446 S + +S+ S + ++ + GT+ +WD + + + H C S+D + A Sbjct: 473 SKISCISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLA 532 Query: 447 SGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRW-IVSGGADSSV 596 SGS D +K+W + + + + ++F+P R+ + G AD V Sbjct: 533 SGSDDAKVKLWSTNLDNSVASIEA-KANVCCVKFSPSSRYHLAFGCADHCV 582 Score = 34.3 bits (77), Expect = 0.28 Identities = 21/86 (24%), Positives = 40/86 (46%) Frame = +3 Query: 129 FVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSE 308 F H V+ AKF + +++ D ++ LW VGKP + S G + + S+ Sbjct: 597 FKGHRKAVSYAKFV--SGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNG 654 Query: 309 VMIGAGAASGTIKIWDIEEAKVVRTF 386 I G+ + ++ ++ +K + TF Sbjct: 655 DYIACGSENNSLYLYYKGLSKTLLTF 680
>POF11_SCHPO (Q09855) F-box/WD-repeat protein pof11| Length = 506 Score = 61.2 bits (147), Expect = 2e-09 Identities = 35/163 (21%), Positives = 77/163 (47%), Gaps = 4/163 (2%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 Q+F A V C ++ +++G +D+ V++W V + L G + V L F Sbjct: 215 QDFRATLDSVYCVQYD---DEIMVSGSKDRTVSVWDVNSRFILYKLYGHSGSVLCLDFCR 271 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 ++ +G++ TI IWD + + ++ + GH N + ++ S S D ++W Sbjct: 272 RRNLLVSGSSDSTIIIWDWQNRRPLKVYFGHTDNVLGVVVSE--NYIISSSRDHTARVWR 329 Query: 483 M----RKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 + + C+H +GH ++ ++++ IV+ +D +++ Sbjct: 330 LDATSPAEACMHVLRGHLASVNSVQYSSKTGLIVTASSDRTLR 372 Score = 58.5 bits (140), Expect = 1e-08 Identities = 37/141 (26%), Positives = 64/141 (45%), Gaps = 4/141 (2%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLS----LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWD 356 +I+ D +W + + + L G + V S+ + S +I ++ T++ WD Sbjct: 316 IISSSRDHTARVWRLDATSPAEACMHVLRGHLASVNSVQYSSKTGLIVTASSDRTLRTWD 375 Query: 357 IEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRID 536 I +R H+ A + G F SGSSD ++I++ + + QGH I Sbjct: 376 ITTGHCIRIIHAHQRGIACAQYN--GKFIVSGSSDLTIRIFEASSGKLLRMLQGHEDLIR 433 Query: 537 VLRFTPDGRWIVSGGADSSVK 599 +RF + IVSGG D +V+ Sbjct: 434 TVRFNDEK--IVSGGYDGTVR 452
>BRWD1_HUMAN (Q9NSI6) Bromodomain and WD-repeat domain-containing protein 1| (WD-repeat protein 9) Length = 2320 Score = 61.2 bits (147), Expect = 2e-09 Identities = 35/115 (30%), Positives = 58/115 (50%), Gaps = 4/115 (3%) Frame = +3 Query: 264 GLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFF 443 G S V ++FD + I G+ +KIW +++ T GH + + + + Sbjct: 184 GHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMI 243 Query: 444 ASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTP----DGRWIVSGGADSSV 596 A+GS D +++W +R + QGHTG I L+F+P R++VS GAD +V Sbjct: 244 AAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTV 298 Score = 52.4 bits (124), Expect = 1e-06 Identities = 29/123 (23%), Positives = 51/123 (41%), Gaps = 4/123 (3%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 + + H S V C F RT + TG +D V +W+ + +L G ++ + ++ + Sbjct: 180 RRILGHLSAVYCVAFD-RTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNY 238 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGD----FFASGSSDTNM 470 MI AG+ I++W + V GH + SL P + S +D + Sbjct: 239 ENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTV 298 Query: 471 KIW 479 W Sbjct: 299 CFW 301 Score = 39.3 bits (90), Expect = 0.009 Identities = 36/172 (20%), Positives = 67/172 (38%), Gaps = 23/172 (13%) Frame = +3 Query: 117 KLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPT-------AVLSLSGLTS 275 K+ E +H V +F R L +G D +W + +SG S Sbjct: 360 KIAELESHTDKVDSIQFCNNGDRFL-SGSRDGTARIWRFEQLEWRSILLDMATRISGDLS 418 Query: 276 PVES---------LSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHP 428 E ++++ ++ ++ +K+W+ +++ GH L++HP Sbjct: 419 SEEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHP 478 Query: 429 FGD-FFASGSSDTNMKIWDMRKKRCIHTY------QGHTGRIDVLRFTPDGR 563 F S D ++ IWD+ K + Y QGH G + +F+ DG+ Sbjct: 479 FDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGH-GAVFDCKFSQDGQ 529 Score = 37.0 bits (84), Expect = 0.044 Identities = 24/109 (22%), Positives = 40/109 (36%) Frame = +3 Query: 273 SPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASG 452 SP + + + G S + K+ R GH S + G +G Sbjct: 145 SPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTG 204 Query: 453 SSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 S D +KIW R + T +GH+ I + + I +G D ++ Sbjct: 205 SDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIR 253 Score = 29.3 bits (64), Expect = 9.1 Identities = 30/127 (23%), Positives = 49/127 (38%), Gaps = 13/127 (10%) Frame = +3 Query: 138 HASDVTCAKFG---KRTSRTLITGGEDQKVNLWAVGKPTAVLS---LSGLTSP---VESL 290 H +T +F K + R +++ G D V W + S L P V+ L Sbjct: 269 HTGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQML 328 Query: 291 --SFDSSEVMIGAGAASGTIKIWDI--EEAKVVRTFTGHRSNCASLDSHPFGDFFASGSS 458 SF + + G+ I+++ + E + + H S+ GD F SGS Sbjct: 329 CSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSR 388 Query: 459 DTNMKIW 479 D +IW Sbjct: 389 DGTARIW 395
>YAGE_SCHPO (Q9UTN4) Hypothetical WD-repeat protein C12G12.14c in chromosome I| Length = 509 Score = 61.2 bits (147), Expect = 2e-09 Identities = 36/157 (22%), Positives = 75/157 (47%), Gaps = 3/157 (1%) Frame = +3 Query: 135 AHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVM 314 AH +V F S+ +T +D + +W T L L+G V+++ + S+ + Sbjct: 162 AHEMEVRDVAFSPNDSK-FVTASDDGSLKVWNFHMSTEELKLTGHGWDVKTVDWHPSKGL 220 Query: 315 IGAGAASGTIKIWDIEEAKVVRTFTGHRSNC--ASLDSHPFGDFFASGSSDTNMKIWDMR 488 + +G+ +K WD + T GH++ AS + ++ A+ S D+ +++D+R Sbjct: 221 LASGSKDNLVKFWDPRTGTCIATLHGHKNTIMQASFQKNFGSNYLATVSRDSTCRVFDLR 280 Query: 489 KKRCIHTYQGHTGRIDVLRFTP-DGRWIVSGGADSSV 596 + + +GH ++ + + P + +GG+D SV Sbjct: 281 AMKDVRVLRGHEKDVNCVTWHPLYPNLLTTGGSDGSV 317 Score = 33.1 bits (74), Expect = 0.63 Identities = 32/136 (23%), Positives = 52/136 (38%), Gaps = 6/136 (4%) Frame = +3 Query: 90 SRMATKRAYKLQEFV------AHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAV 251 SR +T R + L+ H DV C + L TGG D VN +++ +P + Sbjct: 269 SRDSTCRVFDLRAMKDVRVLRGHEKDVNCVTWHPLYPNLLTTGGSDGSVNHYSLDEP-PL 327 Query: 252 LSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPF 431 LS +++ +S ++ A +I A H S+ HP Sbjct: 328 LSQQKYHEKHPNVTLSASSYLLYPTA--------EIPFA--------HDLGIWSMQYHPL 371 Query: 432 GDFFASGSSDTNMKIW 479 G +GS+D + W Sbjct: 372 GHLLCTGSNDKTTRFW 387 Score = 31.2 bits (69), Expect = 2.4 Identities = 28/141 (19%), Positives = 51/141 (36%), Gaps = 2/141 (1%) Frame = +3 Query: 183 RTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWD-- 356 R L+TG + LW L V + + + +G G +K ++ Sbjct: 94 RRLLTGSSTGEFTLWNGLTFNFELINQSHDYAVRCAEWSTDGRWLISGDGGGMVKYFEPN 153 Query: 357 IEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRID 536 + K+V+ H + P F + S D ++K+W+ GH + Sbjct: 154 LNNVKIVQA---HEMEVRDVAFSPNDSKFVTASDDGSLKVWNFHMSTEELKLTGHGWDVK 210 Query: 537 VLRFTPDGRWIVSGGADSSVK 599 + + P + SG D+ VK Sbjct: 211 TVDWHPSKGLLASGSKDNLVK 231
>PFS2_YEAST (P42841) Protein PFS2| Length = 465 Score = 61.2 bits (147), Expect = 2e-09 Identities = 41/156 (26%), Positives = 65/156 (41%), Gaps = 1/156 (0%) Frame = +3 Query: 135 AHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVM 314 AH S VT K+ S +I+G D + +W + T + ++F S++ Sbjct: 133 AHDSAVTTMKYS-HDSDWMISGDADGMIKIWQPNFSMVKEIDAAHTESIRDMAFSSNDSK 191 Query: 315 IGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKK 494 + +KIW+ K R +GH + S D HP AS S D +K+WD R Sbjct: 192 FVTCSDDNILKIWNFSNGKQERVLSGHHWDVKSCDWHPEMGLIASASKDNLVKLWDPRSG 251 Query: 495 RCIHTYQGHTGRIDVLRFTP-DGRWIVSGGADSSVK 599 CI + + RF P G +++ D S + Sbjct: 252 NCISSILKFKHTVLKTRFQPTKGNLLMAISKDKSCR 287 Score = 40.4 bits (93), Expect = 0.004 Identities = 30/139 (21%), Positives = 50/139 (35%) Frame = +3 Query: 183 RTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIE 362 R L+ + +LW T + S V ++ + + +G A G IKIW Sbjct: 106 RRLVVATYSGEFSLWNASSFTFETLMQAHDSAVTTMKYSHDSDWMISGDADGMIKIWQPN 165 Query: 363 EAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVL 542 + V H + + F + S D +KIW+ + GH + Sbjct: 166 FSMVKEIDAAHTESIRDMAFSSNDSKFVTCSDDNILKIWNFSNGKQERVLSGHHWDVKSC 225 Query: 543 RFTPDGRWIVSGGADSSVK 599 + P+ I S D+ VK Sbjct: 226 DWHPEMGLIASASKDNLVK 244
>COPA_HUMAN (P53621) Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP)| (HEPCOP) (HEP-COP) [Contains: Xenin (Xenopsin-related peptide); Proxenin] Length = 1224 Score = 61.2 bits (147), Expect = 2e-09 Identities = 30/107 (28%), Positives = 48/107 (44%) Frame = +3 Query: 279 VESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSS 458 V+ LSF I +G I++WD ++ F H +D H F SG Sbjct: 12 VKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGD 71 Query: 459 DTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 D +K+W+ + +RC+ T GH I F + WI+S D +++ Sbjct: 72 DYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIR 118 Score = 56.2 bits (134), Expect = 7e-08 Identities = 44/188 (23%), Positives = 69/188 (36%), Gaps = 28/188 (14%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 + +F H V F K+ ++GG+D K+ +W + +L G + + F Sbjct: 44 IDKFDEHDGPVRGIDFHKQQP-LFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFH 102 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 I + + TI++W+ + V TGH HP D S S D +++W Sbjct: 103 HEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPTEDLVVSASLDQTVRVW 162 Query: 480 D---MRKKRCI-------------------------HTYQGHTGRIDVLRFTPDGRWIVS 575 D +RKK H +GH ++ F P IVS Sbjct: 163 DISGLRKKNLSPGAVESDVRGITGVDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVS 222 Query: 576 GGADSSVK 599 G D VK Sbjct: 223 GADDRQVK 230 Score = 54.3 bits (129), Expect = 3e-07 Identities = 46/177 (25%), Positives = 72/177 (40%), Gaps = 30/177 (16%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVG-------KPTAVLS------------- 257 H V CA+F T +++ DQ V +W + P AV S Sbjct: 134 HNHYVMCAQFHP-TEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITGVDLFGT 192 Query: 258 --------LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKV--VRTFTGHRSNC 407 L G V +F + +I +GA +KIW + E+K V T GH +N Sbjct: 193 TDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNV 252 Query: 408 ASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSG 578 + HP + S S D ++++WDM K+ + T++ R VL P+ +G Sbjct: 253 SCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAHPNLNLFAAG 309 Score = 53.1 bits (126), Expect = 6e-07 Identities = 28/137 (20%), Positives = 56/137 (40%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 ++T + + LW T + PV + F + + +G IK+W+ + Sbjct: 24 ILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLR 83 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 + + T GH + H + S S D +++W+ + + C+ GH + +F Sbjct: 84 RCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQF 143 Query: 549 TPDGRWIVSGGADSSVK 599 P +VS D +V+ Sbjct: 144 HPTEDLVVSASLDQTVR 160
>COPA_BOVIN (Q27954) Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP)| (HEPCOP) (HEP-COP) [Contains: Xenin (Xenopsin-related peptide); Proxenin] Length = 1224 Score = 61.2 bits (147), Expect = 2e-09 Identities = 30/107 (28%), Positives = 48/107 (44%) Frame = +3 Query: 279 VESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSS 458 V+ LSF I +G I++WD ++ F H +D H F SG Sbjct: 12 VKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGD 71 Query: 459 DTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 D +K+W+ + +RC+ T GH I F + WI+S D +++ Sbjct: 72 DYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIR 118 Score = 56.2 bits (134), Expect = 7e-08 Identities = 44/188 (23%), Positives = 69/188 (36%), Gaps = 28/188 (14%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 + +F H V F K+ ++GG+D K+ +W + +L G + + F Sbjct: 44 IDKFDEHDGPVRGIDFHKQQP-LFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFH 102 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 I + + TI++W+ + V TGH HP D S S D +++W Sbjct: 103 HEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVW 162 Query: 480 D---MRKKRCI-------------------------HTYQGHTGRIDVLRFTPDGRWIVS 575 D +RKK H +GH ++ F P IVS Sbjct: 163 DISGLRKKNLSPGAVESDVRGITGVDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVS 222 Query: 576 GGADSSVK 599 G D VK Sbjct: 223 GADDRQVK 230 Score = 53.5 bits (127), Expect = 4e-07 Identities = 28/137 (20%), Positives = 56/137 (40%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 ++T + + LW T + PV + F + + +G IK+W+ + Sbjct: 24 ILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLR 83 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 + + T GH + H + S S D +++W+ + + C+ GH + +F Sbjct: 84 RCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQF 143 Query: 549 TPDGRWIVSGGADSSVK 599 P +VS D +V+ Sbjct: 144 HPSEDLVVSASLDQTVR 160 Score = 52.8 bits (125), Expect = 8e-07 Identities = 45/177 (25%), Positives = 72/177 (40%), Gaps = 30/177 (16%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVG-------KPTAVLS------------- 257 H V CA+F + +++ DQ V +W + P AV S Sbjct: 134 HNHYVMCAQFHP-SEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITGVDLFGT 192 Query: 258 --------LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKV--VRTFTGHRSNC 407 L G V +F + +I +GA +KIW + E+K V T GH +N Sbjct: 193 TDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNV 252 Query: 408 ASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSG 578 + HP + S S D ++++WDM K+ + T++ R VL P+ +G Sbjct: 253 SCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAHPNLNLFAAG 309
>GBLP_CHLRE (P25387) Guanine nucleotide-binding protein beta subunit-like| protein Length = 318 Score = 60.8 bits (146), Expect = 3e-09 Identities = 43/150 (28%), Positives = 68/150 (45%), Gaps = 9/150 (6%) Frame = +3 Query: 177 TSRTLITGGEDQKVNLWAVGKPT-----AVLSLSGLTSPVESLSFDSSEVMIGAGAASGT 341 +S TL++ D+ V +W + + A +L G + V+ + S G+ GT Sbjct: 28 SSNTLLSASRDKSVLVWELERSESNYGYARKALRGHSHFVQDVVISSDGQFCLTGSWDGT 87 Query: 342 IKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDM--RKKRCIHTYQ 515 +++WD+ R F GH + S+ SGS D +K+W+ K I + Sbjct: 88 LRLWDLNTGTTTRRFVGHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLGECKYTIGEPE 147 Query: 516 GHTGRIDVLRFTP--DGRWIVSGGADSSVK 599 GHT + +RF+P IVSGG D VK Sbjct: 148 GHTEWVSCVRFSPMTTNPIIVSGGWDKMVK 177 Score = 57.8 bits (138), Expect = 2e-08 Identities = 37/136 (27%), Positives = 59/136 (43%), Gaps = 4/136 (2%) Frame = +3 Query: 192 ITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWD-IEEA 368 +TG D + LW + T G T V S++F I +G+ TIK+W+ + E Sbjct: 80 LTGSWDGTLRLWDLNTGTTTRRFVGHTKDVLSVAFSVDNRQIVSGSRDKTIKLWNTLGEC 139 Query: 369 K-VVRTFTGHRS--NCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDV 539 K + GH +C SG D +K+W++ + + GH G ++ Sbjct: 140 KYTIGEPEGHTEWVSCVRFSPMTTNPIIVSGGWDKMVKVWNLTNCKLKNNLVGHHGYVNT 199 Query: 540 LRFTPDGRWIVSGGAD 587 + +PDG SGG D Sbjct: 200 VTVSPDGSLCASGGKD 215 Score = 55.8 bits (133), Expect = 9e-08 Identities = 40/169 (23%), Positives = 73/169 (43%), Gaps = 10/169 (5%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLW--------AVGKPTAVLSLSGLTSP 278 + FV H DV F +R +++G D+ + LW +G+P G T Sbjct: 100 RRFVGHTKDVLSVAFSV-DNRQIVSGSRDKTIKLWNTLGECKYTIGEP------EGHTEW 152 Query: 279 VESLSFD--SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASG 452 V + F ++ +I +G +K+W++ K+ GH ++ P G ASG Sbjct: 153 VSCVRFSPMTTNPIIVSGGWDKMVKVWNLTNCKLKNNLVGHHGYVNTVTVSPDGSLCASG 212 Query: 453 SSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 D +WD+ + + +++ I L F+P+ W+ + SS+K Sbjct: 213 GKDGIAMLWDLAEGKRLYSLDA-GDVIHCLCFSPNRYWLCA-ATQSSIK 259 Score = 47.4 bits (111), Expect = 3e-05 Identities = 29/122 (23%), Positives = 57/122 (46%), Gaps = 7/122 (5%) Frame = +3 Query: 255 SLSGLTSPVESLS--FDSSEVMIGAGAASGTIKIWDIEEAK-----VVRTFTGHRSNCAS 413 +L G T+ V +++ D S + + + ++ +W++E ++ + GH Sbjct: 10 TLKGHTNWVTAIATPLDPSSNTLLSASRDKSVLVWELERSESNYGYARKALRGHSHFVQD 69 Query: 414 LDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSS 593 + G F +GS D +++WD+ + GHT + + F+ D R IVSG D + Sbjct: 70 VVISSDGQFCLTGSWDGTLRLWDLNTGTTTRRFVGHTKDVLSVAFSVDNRQIVSGSRDKT 129 Query: 594 VK 599 +K Sbjct: 130 IK 131 Score = 34.3 bits (77), Expect = 0.28 Identities = 27/104 (25%), Positives = 44/104 (42%), Gaps = 9/104 (8%) Frame = +3 Query: 195 TGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKV 374 +GG+D LW + + + SL + L F + + A A +IKIWD+E + Sbjct: 211 SGGKDGIAMLWDLAEGKRLYSLDA-GDVIHCLCFSPNRYWLCA-ATQSSIKIWDLESKSI 268 Query: 375 VR------TFTGHRSN---CASLDSHPFGDFFASGSSDTNMKIW 479 V T ++ C SL G SG +D +++W Sbjct: 269 VDDLRPEFNITSKKAQVPYCVSLAWSADGSTLYSGYTDGQIRVW 312
>COPB2_CAEEL (Q20168) Probable coatomer subunit beta' (Beta'-coat protein)| (Beta'-COP) Length = 1000 Score = 60.8 bits (146), Expect = 3e-09 Identities = 44/165 (26%), Positives = 75/165 (45%), Gaps = 4/165 (2%) Frame = +3 Query: 117 KLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVL-SLSGLTSPVESLS 293 ++ +F AH SD + T +I+ +D V +W A+ S G T V ++ Sbjct: 91 RVHQFEAH-SDYLRSLVVHPTLPYVISSSDDMLVKMWDWDNKWAMKQSFEGHTHYVMQIA 149 Query: 294 FDSSEVMIGAGAA-SGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGD--FFASGSSDT 464 + + A A+ T+K+W T GH +D + G+ + SG+ D Sbjct: 150 INPKDNNTFATASLDKTVKVWQFGSNVPNFTLEGHEKGVNCVDYYHGGEKPYIISGADDH 209 Query: 465 NMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 +KIWD + K C+ T GH + + F P+ I++G DS+V+ Sbjct: 210 LVKIWDYQNKTCVQTLDGHAQNVSSVCFHPELPLIITGSEDSTVR 254 Score = 60.5 bits (145), Expect = 4e-09 Identities = 40/160 (25%), Positives = 63/160 (39%), Gaps = 2/160 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSF-- 296 Q F H V + + T T D+ V +W G +L G V + + Sbjct: 136 QSFEGHTHYVMQIAINPKDNNTFATASLDKTVKVWQFGSNVPNFTLEGHEKGVNCVDYYH 195 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 + I +GA +KIWD + V+T GH N +S+ HP +GS D+ +++ Sbjct: 196 GGEKPYIISGADDHLVKIWDYQNKTCVQTLDGHAQNVSSVCFHPELPLIITGSEDSTVRL 255 Query: 477 WDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 W R HT R+ ++ I G + SV Sbjct: 256 WHANTYRQEHTLNYGLERVWCIQAQKGANTIAIGYDEGSV 295 Score = 48.1 bits (113), Expect = 2e-05 Identities = 40/174 (22%), Positives = 69/174 (39%), Gaps = 2/174 (1%) Frame = +3 Query: 84 LPSRMATKRAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLS 263 +P R+ KR + +A + V C L+ + V++W T V S Sbjct: 1 MPLRLDVKR-----KLLARSDRVKCVDLHP-VETWLLAALYNGNVHIWNYETQTLVKSFE 54 Query: 264 GLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFF 443 PV + F + + G+ I++++ + V F H SL HP + Sbjct: 55 VCDVPVRAAKFVPRKSWVVTGSDDMHIRVFNYNTLERVHQFEAHSDYLRSLVVHPTLPYV 114 Query: 444 ASGSSDTNMKIWDMRKKRCI-HTYQGHTGRIDVLRFTP-DGRWIVSGGADSSVK 599 S S D +K+WD K + +++GHT + + P D + D +VK Sbjct: 115 ISSSDDMLVKMWDWDNKWAMKQSFEGHTHYVMQIAINPKDNNTFATASLDKTVK 168
>BRWD1_MOUSE (Q921C3) Bromodomain and WD-repeat domain-containing protein 1| (WD-repeat protein 9) Length = 2304 Score = 60.8 bits (146), Expect = 3e-09 Identities = 35/115 (30%), Positives = 58/115 (50%), Gaps = 4/115 (3%) Frame = +3 Query: 264 GLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFF 443 G S V ++FD + I G+ +KIW +++ T GH + + + + Sbjct: 184 GHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTLI 243 Query: 444 ASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTP----DGRWIVSGGADSSV 596 A+GS D +++W +R + QGHTG I L+F+P R++VS GAD +V Sbjct: 244 AAGSCDKVIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGPQRYMVSTGADGTV 298 Score = 51.6 bits (122), Expect = 2e-06 Identities = 28/123 (22%), Positives = 51/123 (41%), Gaps = 4/123 (3%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDS 302 + + H S V C F RT + TG +D V +W+ + +L G ++ + ++ + Sbjct: 180 RRILGHLSAVYCVAFD-RTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNY 238 Query: 303 SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGD----FFASGSSDTNM 470 +I AG+ I++W + V GH + SL P + S +D + Sbjct: 239 ENTLIAAGSCDKVIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGPQRYMVSTGADGTV 298 Query: 471 KIW 479 W Sbjct: 299 CFW 301 Score = 39.3 bits (90), Expect = 0.009 Identities = 41/172 (23%), Positives = 65/172 (37%), Gaps = 23/172 (13%) Frame = +3 Query: 117 KLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPT--AVL-----SLSGLTS 275 K+ E +H V +F R L +G D +W + ++L +SG TS Sbjct: 360 KIAELESHTDKVDSIQFCNNGDRFL-SGSRDGTARIWRFEQLEWRSILLDMSARISGDTS 418 Query: 276 PVESLSFDSSEVMIGAGAASGTI---------KIWDIEEAKVVRTFTGHRSNCASLDSHP 428 E MI T+ K+W +++ GH L++HP Sbjct: 419 SEEERFMKPKVTMIAWNQDDSTVVTAVNDHVLKVWSSYTGQLLHNLLGHADEVFVLETHP 478 Query: 429 FGD-FFASGSSDTNMKIWDMRKKRCIHTY------QGHTGRIDVLRFTPDGR 563 F S D ++ IWD+ K + Y QGH G + +F+ DG+ Sbjct: 479 FDSRIMLSAGHDGSIFIWDITKGIKMKHYFNMIEGQGH-GAVFDCKFSQDGQ 529 Score = 36.2 bits (82), Expect = 0.074 Identities = 20/80 (25%), Positives = 33/80 (41%) Frame = +3 Query: 360 EEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDV 539 + K+ R GH S + G +GS D +KIW R + T +GH+ I Sbjct: 174 QHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISD 233 Query: 540 LRFTPDGRWIVSGGADSSVK 599 + + I +G D ++ Sbjct: 234 MAVNYENTLIAAGSCDKVIR 253
>TLE2_MOUSE (Q9WVB2) Transducin-like enhancer protein 2| Length = 767 Score = 60.8 bits (146), Expect = 3e-09 Identities = 34/141 (24%), Positives = 66/141 (46%), Gaps = 2/141 (1%) Frame = +3 Query: 183 RTLITGGEDQKVNLWAVGKPTAVLS--LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWD 356 ++LI GGE +++W + PT + L+ +L+ + + + G I +WD Sbjct: 540 QSLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWD 599 Query: 357 IEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRID 536 ++ +VR F GH + +D +G +G D ++ WD+R+ R + + + +I Sbjct: 600 LQNQAMVRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWDLREGRQLQQHD-FSSQIF 658 Query: 537 VLRFTPDGRWIVSGGADSSVK 599 L P+ W+ G S V+ Sbjct: 659 SLGHCPNQDWLAVGMESSHVE 679 Score = 55.5 bits (132), Expect = 1e-07 Identities = 42/163 (25%), Positives = 73/163 (44%), Gaps = 7/163 (4%) Frame = +3 Query: 132 VAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKP---TAVLSLSGLTSP--VESLSF 296 +AH +V CA +++ + TGG+ V +W VG+P T V L L + S Sbjct: 478 LAHG-EVVCAVTISSSTQHVYTGGKGC-VKVWDVGQPGSKTPVAQLDCLNRDNYIRSCKL 535 Query: 297 DSSEVMIGAGAASGTIKIWDIEEA--KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNM 470 + G + T+ IWD+ ++ T C +L P S SD N+ Sbjct: 536 LPDGQSLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNI 595 Query: 471 KIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 +WD++ + + +QGHT + + G + +GG D++V+ Sbjct: 596 VVWDLQNQAMVRQFQGHTDGASCIDISDYGTRLWTGGLDNTVR 638
>GBLP_BRANA (Q39336) Guanine nucleotide-binding protein beta subunit-like| protein Length = 327 Score = 60.8 bits (146), Expect = 3e-09 Identities = 38/140 (27%), Positives = 62/140 (44%), Gaps = 5/140 (3%) Frame = +3 Query: 192 ITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWD-IEEA 368 ++G D ++ LW + + G T V S++F I + + TIK+W+ + E Sbjct: 79 LSGSWDGELRLWDLAAGVSTRRFVGHTKDVLSVAFSLDNRQIVSASRDRTIKLWNTLGEC 138 Query: 369 K--VVRTFTGHRS--NCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRID 536 K + GHR +C + S S D +K+W++ + T GHTG + Sbjct: 139 KYTISEGGEGHRDWVSCVRFSPNTLQPTIVSASCDKTVKVWNLSNCKLRSTLAGHTGYVS 198 Query: 537 VLRFTPDGRWIVSGGADSSV 596 + +PDG SGG D V Sbjct: 199 TVAVSPDGSLCASGGKDGVV 218 Score = 57.4 bits (137), Expect = 3e-08 Identities = 37/154 (24%), Positives = 73/154 (47%), Gaps = 5/154 (3%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLW-AVGKPTAVLSLSGLTSP--VESLS 293 + FV H DV F +R +++ D+ + LW +G+ +S G V + Sbjct: 99 RRFVGHTKDVLSVAFSL-DNRQIVSASRDRTIKLWNTLGECKYTISEGGEGHRDWVSCVR 157 Query: 294 FDSSEVM--IGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTN 467 F + + I + + T+K+W++ K+ T GH +++ P G ASG D Sbjct: 158 FSPNTLQPTIVSASCDKTVKVWNLSNCKLRSTLAGHTGYVSTVAVSPDGSLCASGGKDGV 217 Query: 468 MKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWI 569 + +WD+ + + +++ + ++ I L FTP+ W+ Sbjct: 218 VLLWDLAEGKKLYSLEANS-VIHALCFTPNRYWL 250 Score = 52.0 bits (123), Expect = 1e-06 Identities = 41/166 (24%), Positives = 70/166 (42%), Gaps = 11/166 (6%) Frame = +3 Query: 135 AHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLS-----LSGLTSPVESLSFD 299 AH VT S T+++ D+ + +W + K L+G + VE + Sbjct: 13 AHTDMVTAIATPIDNSDTIVSASRDKSIIVWKLTKDDKSYGVRQRRLTGHSHFVEDVVLS 72 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 S +G+ G +++WD+ R F GH + S+ S S D +K+W Sbjct: 73 SDGQFALSGSWDGELRLWDLAAGVSTRRFVGHTKDVLSVAFSLDNRQIVSASRDRTIKLW 132 Query: 480 DMRKKRCIHTY----QGHTGRIDVLRFTPD--GRWIVSGGADSSVK 599 + + C +T +GH + +RF+P+ IVS D +VK Sbjct: 133 NTLGE-CKYTISEGGEGHRDWVSCVRFSPNTLQPTIVSASCDKTVK 177 Score = 34.7 bits (78), Expect = 0.22 Identities = 30/114 (26%), Positives = 47/114 (41%), Gaps = 19/114 (16%) Frame = +3 Query: 195 TGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKV 374 +GG+D V LW + + + SL S + +L F + + A G IKIWD+E V Sbjct: 211 SGGKDGVVLLWDLAEGKKLYSLEA-NSVIHALCFTPNRYWLCAATEQG-IKIWDLESKTV 268 Query: 375 VRTF------TGHRSN-------------CASLDSHPFGDFFASGSSDTNMKIW 479 V +S+ C SL+ G SG +D +++W Sbjct: 269 VEDLKVDLKAEAEKSDGSGTAATKRKVIYCTSLNWSADGSTLFSGYTDGVIRVW 322
>GBLP_TRYBR (P69104) Guanine nucleotide-binding protein beta subunit-like| protein (Activated protein kinase C receptor homolog) (Track) Length = 318 Score = 60.5 bits (145), Expect = 4e-09 Identities = 39/151 (25%), Positives = 68/151 (45%), Gaps = 3/151 (1%) Frame = +3 Query: 126 EFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAV-GKPTAVLSLSGLTSPVESLSFDS 302 +F+ H DV F +R +++GG D + +W V G+ LS T V + F Sbjct: 104 KFLGHTKDVLSVAFSP-DNRQIVSGGRDNALRVWNVKGECMHTLSRGAHTDWVSCVRFSP 162 Query: 303 S--EVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 S +I +G +K+WD+ ++V GH + S+ P G AS D ++ Sbjct: 163 SLDAPVIVSGGWDNLVKVWDLATGRLVTDLKGHTNYVTSVTVSPDGSLCASSDKDGVARL 222 Query: 477 WDMRKKRCIHTYQGHTGRIDVLRFTPDGRWI 569 WD+ K + + I+ + F+P+ W+ Sbjct: 223 WDLTKGEAL-SEMAAGAPINQICFSPNRYWM 252 Score = 52.0 bits (123), Expect = 1e-06 Identities = 23/74 (31%), Positives = 44/74 (59%) Frame = +3 Query: 378 RTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPD 557 R GH + + + G+F S S D ++++W+++ +C + + GHT + + F+PD Sbjct: 61 RRLEGHSAFVSDVALSNNGNFAVSASWDHSLRLWNLQNGQCQYKFLGHTKDVLSVAFSPD 120 Query: 558 GRWIVSGGADSSVK 599 R IVSGG D++++ Sbjct: 121 NRQIVSGGRDNALR 134 Score = 50.8 bits (120), Expect = 3e-06 Identities = 37/175 (21%), Positives = 68/175 (38%), Gaps = 8/175 (4%) Frame = +3 Query: 87 PSRMATKRAY-----KLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAV 251 P R +++ +Y +L+ A SDV + G ++ D + LW + Sbjct: 47 PDRHSSECSYGLPDRRLEGHSAFVSDVALSNNGNFA----VSASWDHSLRLWNLQNGQCQ 102 Query: 252 LSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSN---CASLDS 422 G T V S++F I +G +++W+++ + G ++ C Sbjct: 103 YKFLGHTKDVLSVAFSPDNRQIVSGGRDNALRVWNVKGECMHTLSRGAHTDWVSCVRFSP 162 Query: 423 HPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGAD 587 SG D +K+WD+ R + +GHT + + +PDG S D Sbjct: 163 SLDAPVIVSGGWDNLVKVWDLATGRLVTDLKGHTNYVTSVTVSPDGSLCASSDKD 217
>GBLP_TRYBB (P69103) Guanine nucleotide-binding protein beta subunit-like| protein (Activated protein kinase C receptor homolog) Length = 318 Score = 60.5 bits (145), Expect = 4e-09 Identities = 39/151 (25%), Positives = 68/151 (45%), Gaps = 3/151 (1%) Frame = +3 Query: 126 EFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAV-GKPTAVLSLSGLTSPVESLSFDS 302 +F+ H DV F +R +++GG D + +W V G+ LS T V + F Sbjct: 104 KFLGHTKDVLSVAFSP-DNRQIVSGGRDNALRVWNVKGECMHTLSRGAHTDWVSCVRFSP 162 Query: 303 S--EVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 S +I +G +K+WD+ ++V GH + S+ P G AS D ++ Sbjct: 163 SLDAPVIVSGGWDNLVKVWDLATGRLVTDLKGHTNYVTSVTVSPDGSLCASSDKDGVARL 222 Query: 477 WDMRKKRCIHTYQGHTGRIDVLRFTPDGRWI 569 WD+ K + + I+ + F+P+ W+ Sbjct: 223 WDLTKGEAL-SEMAAGAPINQICFSPNRYWM 252 Score = 52.0 bits (123), Expect = 1e-06 Identities = 23/74 (31%), Positives = 44/74 (59%) Frame = +3 Query: 378 RTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPD 557 R GH + + + G+F S S D ++++W+++ +C + + GHT + + F+PD Sbjct: 61 RRLEGHSAFVSDVALSNNGNFAVSASWDHSLRLWNLQNGQCQYKFLGHTKDVLSVAFSPD 120 Query: 558 GRWIVSGGADSSVK 599 R IVSGG D++++ Sbjct: 121 NRQIVSGGRDNALR 134 Score = 50.8 bits (120), Expect = 3e-06 Identities = 37/175 (21%), Positives = 68/175 (38%), Gaps = 8/175 (4%) Frame = +3 Query: 87 PSRMATKRAY-----KLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAV 251 P R +++ +Y +L+ A SDV + G ++ D + LW + Sbjct: 47 PDRHSSECSYGLPDRRLEGHSAFVSDVALSNNGNFA----VSASWDHSLRLWNLQNGQCQ 102 Query: 252 LSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSN---CASLDS 422 G T V S++F I +G +++W+++ + G ++ C Sbjct: 103 YKFLGHTKDVLSVAFSPDNRQIVSGGRDNALRVWNVKGECMHTLSRGAHTDWVSCVRFSP 162 Query: 423 HPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGAD 587 SG D +K+WD+ R + +GHT + + +PDG S D Sbjct: 163 SLDAPVIVSGGWDNLVKVWDLATGRLVTDLKGHTNYVTSVTVSPDGSLCASSDKD 217
>COPB2_YEAST (P41811) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| Length = 889 Score = 60.5 bits (145), Expect = 4e-09 Identities = 48/158 (30%), Positives = 67/158 (42%), Gaps = 6/158 (3%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLS-GLTSPVESLSF- 296 Q F H V C F + T +G D+ V +W++G+ T +L+ G V + + Sbjct: 134 QTFEGHEHFVMCVAFNPKDPSTFASGCLDRTVKVWSLGQSTPNFTLTTGQERGVNYVDYY 193 Query: 297 --DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNM 470 MI A + TIKIWD + V T GH SN + HP SGS D + Sbjct: 194 PLPDKPYMITA-SDDLTIKIWDYQTKSCVATLEGHMSNVSFAVFHPTLPIIISGSEDGTL 252 Query: 471 KIWDMRKKRCIHTYQGHTGRIDVLRFTPDGR--WIVSG 578 KIW+ + T R + P GR +I SG Sbjct: 253 KIWNSSTYKVEKTLNVGLERSWCIATHPTGRKNYIASG 290 Score = 57.4 bits (137), Expect = 3e-08 Identities = 42/166 (25%), Positives = 73/166 (43%), Gaps = 5/166 (3%) Frame = +3 Query: 117 KLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAV-LSLSGLTSPVESLS 293 K+ +F AH + T +++G +D V LW A+ + G V ++ Sbjct: 89 KVVDFEAHPDYIRSIAVHP-TKPYVLSGSDDLTVKLWNWENNWALEQTFEGHEHFVMCVA 147 Query: 294 FDSSEVM-IGAGAASGTIKIWDIEEAKVVRTFT-GHRSNCASLDSHPFGD--FFASGSSD 461 F+ + +G T+K+W + ++ T T G +D +P D + + S D Sbjct: 148 FNPKDPSTFASGCLDRTVKVWSLGQSTPNFTLTTGQERGVNYVDYYPLPDKPYMITASDD 207 Query: 462 TNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 +KIWD + K C+ T +GH + F P I+SG D ++K Sbjct: 208 LTIKIWDYQTKSCVATLEGHMSNVSFAVFHPTLPIIISGSEDGTLK 253 Score = 50.4 bits (119), Expect = 4e-06 Identities = 34/131 (25%), Positives = 57/131 (43%), Gaps = 2/131 (1%) Frame = +3 Query: 213 KVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTG 392 +V LW V S+ +PV + F + + I G+ I++++ + V F Sbjct: 36 RVELWNYETQVEVRSIQVTETPVRAGKFIARKNWIIVGSDDFRIRVFNYNTGEKVVDFEA 95 Query: 393 HRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCI-HTYQGHTGRIDVLRFTP-DGRW 566 H S+ HP + SGS D +K+W+ + T++GH + + F P D Sbjct: 96 HPDYIRSIAVHPTKPYVLSGSDDLTVKLWNWENNWALEQTFEGHEHFVMCVAFNPKDPST 155 Query: 567 IVSGGADSSVK 599 SG D +VK Sbjct: 156 FASGCLDRTVK 166
>WDR17_HUMAN (Q8IZU2) WD-repeat protein 17| Length = 1322 Score = 60.5 bits (145), Expect = 4e-09 Identities = 37/132 (28%), Positives = 63/132 (47%), Gaps = 2/132 (1%) Frame = +3 Query: 96 MATKRAYKLQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTS 275 +AT L+ F H + V K+ L +G +D V +W + + L+G T+ Sbjct: 551 VATSSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDYTQDACINILNGHTA 610 Query: 276 PVESLSFDSS-EVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDF-FAS 449 PV L +++ ++ +G+ TIK+WD E V T H ++ L HP F AS Sbjct: 611 PVRGLMWNTEIPYLLISGSWDYTIKVWDTREGTCVDTVYDHGADVYGLTCHPSRPFTMAS 670 Query: 450 GSSDTNMKIWDM 485 S D+ +++W + Sbjct: 671 CSRDSTVRLWSL 682 Score = 48.9 bits (115), Expect = 1e-05 Identities = 40/161 (24%), Positives = 69/161 (42%), Gaps = 7/161 (4%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLW--AVGKPTAVLSLSGLTSPVESLSFDS-SE 308 H + V + + + TG ED V ++ A + SG T+ V + + E Sbjct: 520 HPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSPLRE 579 Query: 309 VMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASL---DSHPFGDFFASGSSDTNMKIW 479 ++ +G+ GT++IWD + + GH + L P+ SGS D +K+W Sbjct: 580 GILCSGSDDGTVRIWDYTQDACINILNGHTAPVRGLMWNTEIPY--LLISGSWDYTIKVW 637 Query: 480 DMRKKRCIHTYQGHTGRIDVLRFTPDGRW-IVSGGADSSVK 599 D R+ C+ T H + L P + + S DS+V+ Sbjct: 638 DTREGTCVDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVR 678 Score = 45.4 bits (106), Expect = 1e-04 Identities = 42/198 (21%), Positives = 79/198 (39%), Gaps = 46/198 (23%) Frame = +3 Query: 132 VAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEV 311 + H + KF L T D + +W + TAV + G + SLS+ + Sbjct: 390 LGHVETIFDCKFKPDDPNLLATASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGGL 449 Query: 312 -MIGAGAASGTIKIWDIEEAKVVRTFTGHRSN-----------------CAS-------- 413 I G + IW++++ K+++ F H +N C+S Sbjct: 450 NCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSDGFCIIRT 509 Query: 414 LD-------SHP---FG--------DFFASGSSDTNMKIWDM--RKKRCIHTYQGHTGRI 533 +D HP FG D A+G DTN++++ + + + + GHT ++ Sbjct: 510 IDGKVLHKYKHPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKV 569 Query: 534 DVLRFTPDGRWIVSGGAD 587 ++++P I+ G+D Sbjct: 570 FHVKWSPLREGILCSGSD 587 Score = 40.0 bits (92), Expect = 0.005 Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 1/71 (1%) Frame = +3 Query: 312 MIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFG-DFFASGSSDTNMKIWDMR 488 ++ + GTIK+WDI V T G+ SL P G + A G+S IW+++ Sbjct: 408 LLATASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQ 467 Query: 489 KKRCIHTYQGH 521 K + I + H Sbjct: 468 KGKIIQRFNEH 478
>PWP2_CAEEL (P91341) Periodic tryptophan protein 2 homolog| Length = 910 Score = 60.5 bits (145), Expect = 4e-09 Identities = 37/154 (24%), Positives = 71/154 (46%), Gaps = 3/154 (1%) Frame = +3 Query: 147 DVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAG 326 DVT A+F K T+ L T + + L + V +L +++++++ + + G Sbjct: 275 DVTAARFHKETN-ILATAFNNGVIVLHEIPSFALVHNLRVSEMRIQTVAWNLTGDWLAIG 333 Query: 327 AASGT---IKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKR 497 G+ + +W+ + V H + + P G A+G+ D +KIW+ R Sbjct: 334 CGKGSTAQLVVWEWQSESYVMKQQAHSLRITTAEYSPDGSLMATGAEDGKVKIWNSRSSF 393 Query: 498 CIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 C T+ HT + +++T GR I+S D +V+ Sbjct: 394 CTVTFDEHTSGVTAVKWTQSGRAILSASLDGTVR 427 Score = 51.2 bits (121), Expect = 2e-06 Identities = 40/157 (25%), Positives = 68/157 (43%), Gaps = 2/157 (1%) Frame = +3 Query: 135 AHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVM 314 AH+ +T A++ S + TG ED KV +W ++ TS V ++ + S Sbjct: 358 AHSLRITTAEYSPDGS-LMATGAEDGKVKIWNSRSSFCTVTFDEHTSGVTAVKWTQSGRA 416 Query: 315 IGAGAASGTIKIWDIEEAKVVRTFT-GHRSNCASLDSHPFGDFFASGSSDT-NMKIWDMR 488 I + + GT++ D++ + RT + A+L GD +G+ + N+ IW Sbjct: 417 ILSASLDGTVRAHDLKRYRNFRTLVCPEPTQLATLAVDKAGDLVIAGAKEVFNIYIWSFE 476 Query: 489 KKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 + GH I + G IVSG D ++K Sbjct: 477 TGHLLDILSGHESAISSIDI--HGNHIVSGSWDRTIK 511 Score = 35.0 bits (79), Expect = 0.17 Identities = 38/155 (24%), Positives = 63/155 (40%), Gaps = 20/155 (12%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLS--LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIE 362 L+ G + N++ T L LSG S + S+ + ++ +G+ TIK+W I Sbjct: 459 LVIAGAKEVFNIYIWSFETGHLLDILSGHESAISSIDIHGNHIV--SGSWDRTIKMWTIV 516 Query: 363 EAKVVRTFTGHRS----------NCASLDSHPFGDFFAS------GSSDTNMKIWDMRKK 494 +++ H + A L S FF + GS DT + R Sbjct: 517 DSQAETVEVSHEALDVKFSPAGDEIAVLTSDGVITFFEAKEMINLGSIDTKLDTDPARGS 576 Query: 495 RCIHTYQG--HTGRIDVLRFTPDGRWIVSGGADSS 593 R T Q T +RF+PDG +++GG ++ Sbjct: 577 RDTITRQSAAKTKTFTRIRFSPDGNLLLAGGESNN 611
>REC14_SCHPO (Q09150) Meiotic recombination protein rec14| Length = 302 Score = 60.5 bits (145), Expect = 4e-09 Identities = 42/154 (27%), Positives = 68/154 (44%), Gaps = 5/154 (3%) Frame = +3 Query: 153 TCAKFG-----KRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMI 317 T KFG R +++G + ++ L + LSG TSPV S++F ++ Sbjct: 143 TKGKFGLCIDYSPNGRFIVSGHQTGQLFLISTETGRLFHVLSGHTSPVRSVAFSPGSTLL 202 Query: 318 GAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKR 497 A S I I+D+ V GH + ++ +P GD S + +KIWD+ Sbjct: 203 AAAGDSKMITIYDVLSGDQVGQLRGHAAWIFAVAFNPVGDLLLSADVEGKIKIWDIDTME 262 Query: 498 CIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 CI T G I + + +G + GAD S++ Sbjct: 263 CISTQSETDGAIWAVAWYKNG--FIVAGADKSIR 294 Score = 34.7 bits (78), Expect = 0.22 Identities = 36/155 (23%), Positives = 65/155 (41%), Gaps = 7/155 (4%) Frame = +3 Query: 135 AHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSP----VESLSFDS 302 AH +D+ + L + D K+ W++G L + + +P V L+ Sbjct: 14 AHQADIYSLNV---VAGNLWSASGDSKIKKWSIGDAEHSL-VEEIDTPHKLGVHHLATSL 69 Query: 303 SEVMIGAGAASGTIKIWDIE--EAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 E ++ + + +W+ E E + + H S C S P G A S D + + Sbjct: 70 DENVVVSCGFGQDVYVWNPETNEFRDLGNNAQHPSECWSSCISPDGQTIAFTSVDGRIAV 129 Query: 477 WDMRKKRCIHTYQGHTGRIDV-LRFTPDGRWIVSG 578 WD C + G+ + + ++P+GR+IVSG Sbjct: 130 WD-NPSDCKISELDTKGKFGLCIDYSPNGRFIVSG 163
>CDC20_RAT (Q62623) Cell division cycle protein 20 homolog (p55CDC)| Length = 499 Score = 60.5 bits (145), Expect = 4e-09 Identities = 37/134 (27%), Positives = 68/134 (50%), Gaps = 4/134 (2%) Frame = +3 Query: 207 DQKVNLWAVGKPTAVLSLSGLTSP---VESLSFDSSEVMIGAGAASGTIKIWDIEEAKVV 377 D V LW G +L L + P + S+++ + G ++ +++WD+++ K + Sbjct: 203 DNSVYLWNAGSGD-ILQLLQMEQPGDYISSVAWIKEGNYLAVGTSNAEVQLWDVQQQKRL 261 Query: 378 RTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMR-KKRCIHTYQGHTGRIDVLRFTP 554 R T H + +SL + + +SGS ++ D+R + + T GH+ + LR+ P Sbjct: 262 RNMTSHSARVSSLSWNSY--ILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAP 319 Query: 555 DGRWIVSGGADSSV 596 DGR + SGG D+ V Sbjct: 320 DGRHLASGGNDNIV 333 Score = 52.8 bits (125), Expect = 8e-07 Identities = 38/162 (23%), Positives = 65/162 (40%), Gaps = 8/162 (4%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTA-------VLSLSGLTSPVESLSF 296 H+ +V C R L +GG D VN+W G + G V + Sbjct: 308 HSQEV-CGLRWAPDGRHLASGGNDNIVNVWPSGPGESGWVPLQTFTQHQGAVKAVAWCPW 366 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFAS-GSSDTNMK 473 S+ + G G + I+IW++ + H C+ L S + + + G + + Sbjct: 367 QSNILATGGGTSDRHIRIWNVCSGACLSAVDVHSQVCSILWSPHYKELISGHGFAQNQLV 426 Query: 474 IWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 IW + +GHT R+ L +PDG + S AD +++ Sbjct: 427 IWKYPTMAKVAELKGHTARVLSLTMSPDGATVASAAADETLR 468 Score = 47.8 bits (112), Expect = 2e-05 Identities = 36/140 (25%), Positives = 64/140 (45%), Gaps = 6/140 (4%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L G + +V LW V + + +++ ++ V SLS++S ++ +G+ SG I D+ A Sbjct: 241 LAVGTSNAEVQLWDVQQQKRLRNMTSHSARVSSLSWNS--YILSSGSRSGHIHHHDVRVA 298 Query: 369 KV-VRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRC----IHTYQGHTGRI 533 + V T +GH L P G ASG +D + +W + T+ H G + Sbjct: 299 EHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNIVNVWPSGPGESGWVPLQTFTQHQGAV 358 Query: 534 DVLRFTP-DGRWIVSGGADS 590 + + P + +GG S Sbjct: 359 KAVAWCPWQSNILATGGGTS 378 Score = 46.2 bits (108), Expect = 7e-05 Identities = 36/124 (29%), Positives = 52/124 (41%), Gaps = 4/124 (3%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGG--EDQKVNLWAVGKPTAVLSLSGLTSPVESLS 293 LQ F H V + S L TGG D+ + +W V A LS + S V S+ Sbjct: 348 LQTFTQHQGAVKAVAWCPWQSNILATGGGTSDRHIRIWNVCSG-ACLSAVDVHSQVCSIL 406 Query: 294 FDS--SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTN 467 + E++ G G A + IW V GH + SL P G AS ++D Sbjct: 407 WSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTARVLSLTMSPDGATVASAAADET 466 Query: 468 MKIW 479 +++W Sbjct: 467 LRLW 470
>CDC20_MOUSE (Q9JJ66) Cell division cycle protein 20 homolog (p55CDC) (mmCdc20)| Length = 499 Score = 60.5 bits (145), Expect = 4e-09 Identities = 37/134 (27%), Positives = 68/134 (50%), Gaps = 4/134 (2%) Frame = +3 Query: 207 DQKVNLWAVGKPTAVLSLSGLTSP---VESLSFDSSEVMIGAGAASGTIKIWDIEEAKVV 377 D V LW G +L L + P + S+++ + G ++ +++WD+++ K + Sbjct: 203 DNSVYLWNAGSGD-ILQLLQMEQPGDYISSVAWIKEGNYLAVGTSNAEVQLWDVQQQKRL 261 Query: 378 RTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMR-KKRCIHTYQGHTGRIDVLRFTP 554 R T H + +SL + + +SGS ++ D+R + + T GH+ + LR+ P Sbjct: 262 RNMTSHSARVSSLSWNSY--ILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAP 319 Query: 555 DGRWIVSGGADSSV 596 DGR + SGG D+ V Sbjct: 320 DGRHLASGGNDNIV 333 Score = 52.4 bits (124), Expect = 1e-06 Identities = 38/162 (23%), Positives = 65/162 (40%), Gaps = 8/162 (4%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTA-------VLSLSGLTSPVESLSF 296 H+ +V C R L +GG D VN+W G + G V + Sbjct: 308 HSQEV-CGLRWAPDGRHLASGGNDNIVNVWPSGPGESGWAPLQTFTQHQGAVKAVAWCPW 366 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFAS-GSSDTNMK 473 S+ + G G + I+IW++ + H C+ L S + + + G + + Sbjct: 367 QSNILATGGGTSDRHIRIWNVCSGACLSAVDVHSQVCSILWSPHYKELISGHGFAQNQLV 426 Query: 474 IWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 IW + +GHT R+ L +PDG + S AD +++ Sbjct: 427 IWKYPTMAKVAELKGHTARVLGLTMSPDGATVASAAADETLR 468 Score = 47.8 bits (112), Expect = 2e-05 Identities = 36/140 (25%), Positives = 64/140 (45%), Gaps = 6/140 (4%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L G + +V LW V + + +++ ++ V SLS++S ++ +G+ SG I D+ A Sbjct: 241 LAVGTSNAEVQLWDVQQQKRLRNMTSHSARVSSLSWNS--YILSSGSRSGHIHHHDVRVA 298 Query: 369 KV-VRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRC----IHTYQGHTGRI 533 + V T +GH L P G ASG +D + +W + T+ H G + Sbjct: 299 EHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNIVNVWPSGPGESGWAPLQTFTQHQGAV 358 Query: 534 DVLRFTP-DGRWIVSGGADS 590 + + P + +GG S Sbjct: 359 KAVAWCPWQSNILATGGGTS 378 Score = 44.7 bits (104), Expect = 2e-04 Identities = 35/124 (28%), Positives = 51/124 (41%), Gaps = 4/124 (3%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGG--EDQKVNLWAVGKPTAVLSLSGLTSPVESLS 293 LQ F H V + S L TGG D+ + +W V A LS + S V S+ Sbjct: 348 LQTFTQHQGAVKAVAWCPWQSNILATGGGTSDRHIRIWNVCSG-ACLSAVDVHSQVCSIL 406 Query: 294 FDS--SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTN 467 + E++ G G A + IW V GH + L P G AS ++D Sbjct: 407 WSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTARVLGLTMSPDGATVASAAADET 466 Query: 468 MKIW 479 +++W Sbjct: 467 LRLW 470
>GBLP_ARATH (O24456) Guanine nucleotide-binding protein beta subunit-like| protein (WD-40 repeat auxin-dependent protein ARCA) Length = 327 Score = 60.1 bits (144), Expect = 5e-09 Identities = 38/140 (27%), Positives = 62/140 (44%), Gaps = 5/140 (3%) Frame = +3 Query: 192 ITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWD-IEEA 368 ++G D ++ LW + + G T V S++F I + + TIK+W+ + E Sbjct: 79 LSGSWDGELRLWDLAAGVSTRRFVGHTKDVLSVAFSLDNRQIVSASRDRTIKLWNTLGEC 138 Query: 369 K--VVRTFTGHRS--NCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRID 536 K + GHR +C + S S D +K+W++ + T GHTG + Sbjct: 139 KYTISEGGEGHRDWVSCVRFSPNTLQPTIVSASWDKTVKVWNLSNCKLRSTLAGHTGYVS 198 Query: 537 VLRFTPDGRWIVSGGADSSV 596 + +PDG SGG D V Sbjct: 199 TVAVSPDGSLCASGGKDGVV 218 Score = 54.7 bits (130), Expect = 2e-07 Identities = 37/154 (24%), Positives = 73/154 (47%), Gaps = 5/154 (3%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLW-AVGKPTAVLSLSGLTSP--VESLS 293 + FV H DV F +R +++ D+ + LW +G+ +S G V + Sbjct: 99 RRFVGHTKDVLSVAFSL-DNRQIVSASRDRTIKLWNTLGECKYTISEGGEGHRDWVSCVR 157 Query: 294 FDSSEVMIGAGAASG--TIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTN 467 F + + +AS T+K+W++ K+ T GH +++ P G ASG D Sbjct: 158 FSPNTLQPTIVSASWDKTVKVWNLSNCKLRSTLAGHTGYVSTVAVSPDGSLCASGGKDGV 217 Query: 468 MKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWI 569 + +WD+ + + +++ + ++ I L F+P+ W+ Sbjct: 218 VLLWDLAEGKKLYSLEANS-VIHALCFSPNRYWL 250 Score = 50.1 bits (118), Expect = 5e-06 Identities = 41/166 (24%), Positives = 70/166 (42%), Gaps = 11/166 (6%) Frame = +3 Query: 135 AHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKP-----TAVLSLSGLTSPVESLSFD 299 AH VT + +++ D+ + LW + K A L+G + VE + Sbjct: 13 AHTDMVTAIATPIDNADIIVSASRDKSIILWKLTKDDKAYGVAQRRLTGHSHFVEDVVLS 72 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 S +G+ G +++WD+ R F GH + S+ S S D +K+W Sbjct: 73 SDGQFALSGSWDGELRLWDLAAGVSTRRFVGHTKDVLSVAFSLDNRQIVSASRDRTIKLW 132 Query: 480 DMRKKRCIHTY----QGHTGRIDVLRFTPD--GRWIVSGGADSSVK 599 + + C +T +GH + +RF+P+ IVS D +VK Sbjct: 133 NTLGE-CKYTISEGGEGHRDWVSCVRFSPNTLQPTIVSASWDKTVK 177 Score = 34.3 bits (77), Expect = 0.28 Identities = 29/114 (25%), Positives = 47/114 (41%), Gaps = 19/114 (16%) Frame = +3 Query: 195 TGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKV 374 +GG+D V LW + + + SL S + +L F + + A G IKIWD+E + Sbjct: 211 SGGKDGVVLLWDLAEGKKLYSLEA-NSVIHALCFSPNRYWLCAATEHG-IKIWDLESKSI 268 Query: 375 VRTF-------------TGHRSN------CASLDSHPFGDFFASGSSDTNMKIW 479 V +G + C SL+ G SG +D +++W Sbjct: 269 VEDLKVDLKAEAEKADNSGPAATKRKVIYCTSLNWSADGSTLFSGYTDGVIRVW 322
>CDC20_HUMAN (Q12834) Cell division cycle protein 20 homolog (p55CDC)| Length = 499 Score = 60.1 bits (144), Expect = 5e-09 Identities = 37/134 (27%), Positives = 67/134 (50%), Gaps = 4/134 (2%) Frame = +3 Query: 207 DQKVNLWAVGKPTAVLSLSGLTSP---VESLSFDSSEVMIGAGAASGTIKIWDIEEAKVV 377 D V LW+ +L L + P + S+++ + G +S +++WD+++ K + Sbjct: 203 DNSVYLWSASSGD-ILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRL 261 Query: 378 RTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMR-KKRCIHTYQGHTGRIDVLRFTP 554 R T H + SL + + +SGS ++ D+R + + T GH+ + LR+ P Sbjct: 262 RNMTSHSARVGSLSWNSY--ILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAP 319 Query: 555 DGRWIVSGGADSSV 596 DGR + SGG D+ V Sbjct: 320 DGRHLASGGNDNLV 333 Score = 53.1 bits (126), Expect = 6e-07 Identities = 40/162 (24%), Positives = 67/162 (41%), Gaps = 8/162 (4%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLW--AVGKPTAV-----LSLSGLTSPVESLSF 296 H+ +V C R L +GG D VN+W A G+ V G V + Sbjct: 308 HSQEV-CGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPW 366 Query: 297 DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFAS-GSSDTNMK 473 S+ + G G + I+IW++ + H C+ L S + + + G + + Sbjct: 367 QSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSILWSPHYKELISGHGFAQNQLV 426 Query: 474 IWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 IW + +GHT R+ L +PDG + S AD +++ Sbjct: 427 IWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLR 468 Score = 47.0 bits (110), Expect = 4e-05 Identities = 37/124 (29%), Positives = 51/124 (41%), Gaps = 4/124 (3%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGG--EDQKVNLWAVGKPTAVLSLSGLTSPVESLS 293 LQ F H V + S L TGG D+ + +W V A LS S V S+ Sbjct: 348 LQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSG-ACLSAVDAHSQVCSIL 406 Query: 294 FDS--SEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTN 467 + E++ G G A + IW V GH S SL P G AS ++D Sbjct: 407 WSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADET 466 Query: 468 MKIW 479 +++W Sbjct: 467 LRLW 470 Score = 46.2 bits (108), Expect = 7e-05 Identities = 36/140 (25%), Positives = 63/140 (45%), Gaps = 6/140 (4%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L G +V LW V + + +++ ++ V SLS++S ++ +G+ SG I D+ A Sbjct: 241 LAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWNS--YILSSGSRSGHIHHHDVRVA 298 Query: 369 KV-VRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKR----CIHTYQGHTGRI 533 + V T +GH L P G ASG +D + +W + T+ H G + Sbjct: 299 EHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAV 358 Query: 534 DVLRFTP-DGRWIVSGGADS 590 + + P + +GG S Sbjct: 359 KAVAWCPWQSNVLATGGGTS 378
>PRP17_MOUSE (Q9DC48) Pre-mRNA-splicing factor PRP17 (Cell division cycle 40| homolog) Length = 579 Score = 59.7 bits (143), Expect = 6e-09 Identities = 36/157 (22%), Positives = 67/157 (42%), Gaps = 3/157 (1%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAV-GKPTAVLSLSGLTSPVESLSFDSSEVM 314 H V+ + + L++ D K+ LW V G + + G + V + F+++ Sbjct: 287 HTKGVSAVRLFPLSGHLLLSCSMDCKIKLWEVYGDRRCLRTFIGHSKAVRDICFNTAGTQ 346 Query: 315 IGAGAASGTIKIWDIEEAKVVRTFTGHR-SNCASLD-SHPFGDFFASGSSDTNMKIWDMR 488 + A +K+WD E + + FT + C + + F +G SD + WD+R Sbjct: 347 FLSAAYDRYLKLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIR 406 Query: 489 KKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 + Y H G ++ + F + R VS D S++ Sbjct: 407 SGEIVQEYDRHLGAVNTIVFVDENRRFVSTSDDKSLR 443
>THOC3_MOUSE (Q8VE80) THO complex subunit 3 (Tho3)| Length = 351 Score = 59.7 bits (143), Expect = 6e-09 Identities = 29/103 (28%), Positives = 50/103 (48%) Frame = +3 Query: 279 VESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSS 458 V +S+++ M +G I I E K V++ H SNC + P G +FA+GS+ Sbjct: 185 VNEISWNNDNNMFFLTNGNGCINILSYPELKPVQSINAHPSNCICIKFDPMGKYFATGSA 244 Query: 459 DTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGAD 587 D + +WD+ + C+ + + L F+ DG+ + S D Sbjct: 245 DALVSLWDVDELVCVRCFSRLDWPVRTLSFSHDGKMLASASED 287 Score = 50.1 bits (118), Expect = 5e-06 Identities = 30/112 (26%), Positives = 57/112 (50%), Gaps = 3/112 (2%) Frame = +3 Query: 270 TSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVR--TFTGHRSNCASLDSHPFG-DF 440 ++ V S+++ + +G+ T ++ +E+ ++V+ + GH + L HP D Sbjct: 55 SAKVHSVAWSCDGRRLASGSFDKTASVFLLEKDRLVKENNYRGHGDSVDQLCWHPSNPDL 114 Query: 441 FASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 F + S D ++IWD+R +CI T I++ ++PDG+ I G D V Sbjct: 115 FVTASGDKTIRIWDVRTTKCIATVNTKGENINIC-WSPDGQTIAVGNKDDVV 165 Score = 40.8 bits (94), Expect = 0.003 Identities = 26/81 (32%), Positives = 37/81 (45%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 +Q AH S+ C KF + TG D V+LW V + V S L PV +LSF Sbjct: 217 VQSINAHPSNCICIKFDPM-GKYFATGSADALVSLWDVDELVCVRCFSRLDWPVRTLSFS 275 Query: 300 SSEVMIGAGAASGTIKIWDIE 362 M+ + + I I ++E Sbjct: 276 HDGKMLASASEDHFIDIAEVE 296 Score = 35.8 bits (81), Expect = 0.097 Identities = 33/135 (24%), Positives = 54/135 (40%), Gaps = 9/135 (6%) Frame = +3 Query: 216 VNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGH 395 +N+ + + V S++ S + FD G+A + +WD++E VR F+ Sbjct: 206 INILSYPELKPVQSINAHPSNCICIKFDPMGKYFATGSADALVSLWDVDELVCVRCFSRL 265 Query: 396 RSNCASLDSHPFGDFFASGSSD---------TNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 +L G AS S D T K+W+++ + T H R +L F Sbjct: 266 DWPVRTLSFSHDGKMLASASEDHFIDIAEVETGDKLWEVQCESPTFTVAWHPKR-PLLAF 324 Query: 549 TPDGRWIVSGGADSS 593 D + G DSS Sbjct: 325 ACDDK---DGKYDSS 336
>THOC3_HUMAN (Q96J01) THO complex subunit 3 (Tho3) (TEX1 homolog)| Length = 351 Score = 59.7 bits (143), Expect = 6e-09 Identities = 29/103 (28%), Positives = 50/103 (48%) Frame = +3 Query: 279 VESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSS 458 V +S+++ M +G I I E K V++ H SNC + P G +FA+GS+ Sbjct: 185 VNEISWNNDNNMFFLTNGNGCINILSYPELKPVQSINAHPSNCICIKFDPMGKYFATGSA 244 Query: 459 DTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGAD 587 D + +WD+ + C+ + + L F+ DG+ + S D Sbjct: 245 DALVSLWDVDELVCVRCFSRLDWPVRTLSFSHDGKMLASASED 287 Score = 50.1 bits (118), Expect = 5e-06 Identities = 30/112 (26%), Positives = 57/112 (50%), Gaps = 3/112 (2%) Frame = +3 Query: 270 TSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVR--TFTGHRSNCASLDSHPFG-DF 440 ++ V S+++ + +G+ T ++ +E+ ++V+ + GH + L HP D Sbjct: 55 SAKVHSVAWSCDGRRLASGSFDKTASVFLLEKDRLVKENNYRGHGDSVDQLCWHPSNPDL 114 Query: 441 FASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 F + S D ++IWD+R +CI T I++ ++PDG+ I G D V Sbjct: 115 FVTASGDKTIRIWDVRTTKCIATVNTKGENINIC-WSPDGQTIAVGNKDDVV 165 Score = 40.8 bits (94), Expect = 0.003 Identities = 26/81 (32%), Positives = 37/81 (45%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFD 299 +Q AH S+ C KF + TG D V+LW V + V S L PV +LSF Sbjct: 217 VQSINAHPSNCICIKFDPM-GKYFATGSADALVSLWDVDELVCVRCFSRLDWPVRTLSFS 275 Query: 300 SSEVMIGAGAASGTIKIWDIE 362 M+ + + I I ++E Sbjct: 276 HDGKMLASASEDHFIDIAEVE 296 Score = 35.8 bits (81), Expect = 0.097 Identities = 33/135 (24%), Positives = 54/135 (40%), Gaps = 9/135 (6%) Frame = +3 Query: 216 VNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGH 395 +N+ + + V S++ S + FD G+A + +WD++E VR F+ Sbjct: 206 INILSYPELKPVQSINAHPSNCICIKFDPMGKYFATGSADALVSLWDVDELVCVRCFSRL 265 Query: 396 RSNCASLDSHPFGDFFASGSSD---------TNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 +L G AS S D T K+W+++ + T H R +L F Sbjct: 266 DWPVRTLSFSHDGKMLASASEDHFIDIAEVETGDKLWEVQCESPTFTVAWHPKR-PLLAF 324 Query: 549 TPDGRWIVSGGADSS 593 D + G DSS Sbjct: 325 ACDDK---DGKYDSS 336
>GBLP_BIOGL (Q93134) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C) (RACK) Length = 316 Score = 59.7 bits (143), Expect = 6e-09 Identities = 36/152 (23%), Positives = 66/152 (43%), Gaps = 3/152 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLW---AVGKPTAVLSLSGLTSPVESLS 293 + FV H DV F +R +++G D+ + LW V K T + S Sbjct: 99 RRFVGHTKDVLSVAFSA-DNRQIVSGSRDKTIKLWNTLGVCKYTIQDDCHTDWTSCVRFS 157 Query: 294 FDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMK 473 ++ +I + +K+W++ K+ GH ++ P G ASG D+ Sbjct: 158 PNTQNPIIVSSGWDRLVKVWNLTNCKLKTNHYGHTGYVNTVTVSPDGSLCASGGKDSQAM 217 Query: 474 IWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWI 569 +WD+ + + ++T G I+ L F+P+ W+ Sbjct: 218 LWDLNEGKHLYTLDGAGDTINALCFSPNRYWL 249 Score = 55.8 bits (133), Expect = 9e-08 Identities = 34/136 (25%), Positives = 59/136 (43%), Gaps = 3/136 (2%) Frame = +3 Query: 192 ITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWD-IEEA 368 ++G D + LW + G T V S++F + I +G+ TIK+W+ + Sbjct: 79 LSGSWDHTLRLWDLSTGQTTRRFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVC 138 Query: 369 KVVRTFTGHR--SNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVL 542 K H ++C + S D +K+W++ + + GHTG ++ + Sbjct: 139 KYTIQDDCHTDWTSCVRFSPNTQNPIIVSSGWDRLVKVWNLTNCKLKTNHYGHTGYVNTV 198 Query: 543 RFTPDGRWIVSGGADS 590 +PDG SGG DS Sbjct: 199 TVSPDGSLCASGGKDS 214 Score = 46.6 bits (109), Expect = 5e-05 Identities = 37/146 (25%), Positives = 64/146 (43%), Gaps = 9/146 (6%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVL-----SLSGLTSPVESLSFDSSEVMIGAGAASGTIKIW 353 +++ D+ + +W + + + SL G V + S +G+ T+++W Sbjct: 31 ILSASRDKSLIVWRLTRDESSYGVPQKSLHGHGHFVSDVILSSDGQFALSGSWDHTLRLW 90 Query: 354 DIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQG--HTG 527 D+ + R F GH + S+ SGS D +K+W+ C +T Q HT Sbjct: 91 DLSTGQTTRRFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGV-CKYTIQDDCHTD 149 Query: 528 RIDVLRFTPDGR--WIVSGGADSSVK 599 +RF+P+ + IVS G D VK Sbjct: 150 WTSCVRFSPNTQNPIIVSSGWDRLVK 175 Score = 40.4 bits (93), Expect = 0.004 Identities = 26/104 (25%), Positives = 46/104 (44%), Gaps = 7/104 (6%) Frame = +3 Query: 195 TGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKV 374 +GG+D + LW + + + +L G + +L F + + A+ +IKIWD+E V Sbjct: 209 SGGKDSQAMLWDLNEGKHLYTLDGAGDTINALCFSPNRYWLCV-ASGPSIKIWDLEGKVV 267 Query: 375 VRTF-------TGHRSNCASLDSHPFGDFFASGSSDTNMKIWDM 485 V T C SL G +G +D +++W + Sbjct: 268 VDELKPEVMGTTSKAPTCLSLAWSADGQTLFAGYTDKLIRVWQV 311
>YB1C_SCHPO (P87177) Hypothetical WD-repeat protein C3D6.12 in chromosome II| Length = 922 Score = 59.7 bits (143), Expect = 6e-09 Identities = 39/161 (24%), Positives = 64/161 (39%), Gaps = 27/161 (16%) Frame = +3 Query: 198 GGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVV 377 G D + LW G+ +++L+G S V ++ FD + +G+ I +WDI + Sbjct: 82 GYADGSIRLWKDGE--LLITLNGHKSAVTTMDFDKMGTRLASGSMDTDIIVWDIVAETGL 139 Query: 378 RTFTGHRSNCASL---------------------------DSHPFGDFFASGSSDTNMKI 476 GH+ L DS F S D+ MK+ Sbjct: 140 FRLRGHKDQITKLLFITPPSKNTAEETVVDTDIDSGDMDVDSKSSDSFLLSVGKDSFMKL 199 Query: 477 WDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 WD+ + C+ T+ H G I + +PD + ++ G S VK Sbjct: 200 WDLSIQHCVETHVDHQGEIWAMCVSPDAKRCLTAGTGSDVK 240 Score = 47.0 bits (110), Expect = 4e-05 Identities = 40/183 (21%), Positives = 82/183 (44%), Gaps = 17/183 (9%) Frame = +3 Query: 102 TKRAYKLQ--EFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTS 275 T+RA ++ E H +DV + +I G + + LW + + ++ Sbjct: 381 TERASRISAIEIPGHRADVRTLALS--ANHDVILSGANGSLKLWNKKTTSCIRTIE--CG 436 Query: 276 PVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGS 455 V + SF +++ I + SG ++++DI + ++ H L G +FA+ S Sbjct: 437 YVLAASFINNDKCIVSAYKSGELEVYDIASSSLIERIQAHDGAIWDLAVGHDGTYFATAS 496 Query: 456 SDTNMKIWDMRKK--------RCIHTYQ-GHTGRID------VLRFTPDGRWIVSGGADS 590 +D +K+W ++ R + T + T +ID ++ +PDGR++ + D+ Sbjct: 497 ADHTVKLWSLKSSFDFVPGTTRKVTTLKLEQTRQIDFTDDVLAVKISPDGRFVAASLLDN 556 Query: 591 SVK 599 +VK Sbjct: 557 TVK 559 Score = 42.7 bits (99), Expect = 8e-04 Identities = 29/131 (22%), Positives = 55/131 (41%) Frame = +3 Query: 207 DQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTF 386 D V ++ + L+L G PV S+ ++ +A +KIW ++ ++ Sbjct: 555 DNTVKVYYLDSLKFFLNLYGHKLPVLSMDISYDSKLLVTCSADKNVKIWGLDFGDCHKSI 614 Query: 387 TGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRW 566 H+ + + P F + S D ++ WD + I +GH + L P + Sbjct: 615 FAHQDSIMEVTFQPDTYNFFTCSKDREVRYWDGKSFDLILKLRGHHSEVWALAVGP--TF 672 Query: 567 IVSGGADSSVK 599 +VSG D S++ Sbjct: 673 VVSGSHDHSIR 683 Score = 38.5 bits (88), Expect = 0.015 Identities = 30/136 (22%), Positives = 49/136 (36%), Gaps = 15/136 (11%) Frame = +3 Query: 195 TGGEDQKVNLWAV--------GKPTAVLSLS-------GLTSPVESLSFDSSEVMIGAGA 329 T D V LW++ G V +L T V ++ + A Sbjct: 494 TASADHTVKLWSLKSSFDFVPGTTRKVTTLKLEQTRQIDFTDDVLAVKISPDGRFVAASL 553 Query: 330 ASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHT 509 T+K++ ++ K GH+ S+D + S+D N+KIW + C + Sbjct: 554 LDNTVKVYYLDSLKFFLNLYGHKLPVLSMDISYDSKLLVTCSADKNVKIWGLDFGDCHKS 613 Query: 510 YQGHTGRIDVLRFTPD 557 H I + F PD Sbjct: 614 IFAHQDSIMEVTFQPD 629 Score = 36.2 bits (82), Expect = 0.074 Identities = 21/101 (20%), Positives = 42/101 (41%) Frame = +3 Query: 180 SRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDI 359 S+ L+T D+ V +W + S+ + ++F + ++ WD Sbjct: 588 SKLLVTCSADKNVKIWGLDFGDCHKSIFAHQDSIMEVTFQPDTYNFFTCSKDREVRYWDG 647 Query: 360 EEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 + ++ GH S +L P F SGS D ++++W+ Sbjct: 648 KSFDLILKLRGHHSEVWALAVGP--TFVVSGSHDHSIRLWE 686
>WDR16_HUMAN (Q8N1V2) WD-repeat protein 16 (WD40-repeat protein up-regulated in| HCC) Length = 620 Score = 59.7 bits (143), Expect = 6e-09 Identities = 41/162 (25%), Positives = 72/162 (44%), Gaps = 2/162 (1%) Frame = +3 Query: 117 KLQEFVA-HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLS 293 KL+E + H S V+C + KR + +T D +W + + + T + + Sbjct: 452 KLEEALKEHKSSVSCIRV-KRNNEECVTASTDGTCIIWDLVRLRRNQMILANTL-FQCVC 509 Query: 294 FDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCAS-LDSHPFGDFFASGSSDTNM 470 + E I I W++ + V+R G S + +D G F +G +D + Sbjct: 510 YHPEEFQIITSGTDRKIAYWEVFDGTVIRELEGSLSGSINGMDITQEGVHFVTGGNDHLV 569 Query: 471 KIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 K+WD + H GH+G I +R +P ++IVS AD ++ Sbjct: 570 KVWDYNEGEVTHVGVGHSGNITRIRISPGNQYIVSVSADGAI 611 Score = 49.3 bits (116), Expect = 8e-06 Identities = 26/98 (26%), Positives = 40/98 (40%), Gaps = 1/98 (1%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSG-LTSPVESLSFDSSEVMIGAGAASGTIKIWDIEE 365 +IT G D+K+ W V T + L G L+ + + V G +K+WD E Sbjct: 517 IITSGTDRKIAYWEVFDGTVIRELEGSLSGSINGMDITQEGVHFVTGGNDHLVKVWDYNE 576 Query: 366 AKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 +V GH N + P + S S+D + W Sbjct: 577 GEVTHVGVGHSGNITRIRISPGNQYIVSVSADGAILRW 614 Score = 37.7 bits (86), Expect = 0.026 Identities = 21/72 (29%), Positives = 37/72 (51%), Gaps = 6/72 (8%) Frame = +3 Query: 390 GHRSNCASLDSHPFGDFFASGSSD-----TNMKIWDMRKKRCIHTYQGHTGRIDVLRFTP 554 GH +N + L G++ ASG ++ +WD + + + H G+I+ L F+P Sbjct: 62 GHGNNVSCLAISRSGEYIASGQVTFMGFKADIILWDYKNRELLARLSLHKGKIEALAFSP 121 Query: 555 DGRWIVS-GGAD 587 + ++VS GG D Sbjct: 122 NDLYLVSLGGPD 133 Score = 30.4 bits (67), Expect = 4.1 Identities = 25/95 (26%), Positives = 45/95 (47%), Gaps = 12/95 (12%) Frame = +3 Query: 114 YKLQEFVA----HASDVTCAKFGKRTSRTLITGG-EDQKVNLWAV-------GKPTAVLS 257 YK +E +A H + F + GG +D V +W++ G P A L+ Sbjct: 98 YKNRELLARLSLHKGKIEALAFSPNDLYLVSLGGPDDGSVVVWSIAKRDAICGSPAAGLN 157 Query: 258 LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIE 362 + T+ + S D E+ + AG +GTI++W+++ Sbjct: 158 VGNATNVIFSRCRD--EMFMTAG--NGTIRVWELD 188 Score = 30.0 bits (66), Expect = 5.3 Identities = 27/145 (18%), Positives = 63/145 (43%), Gaps = 4/145 (2%) Frame = +3 Query: 174 RTSRTLITGGEDQKVNLWA--VGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIK 347 R +++I+ D K+ +A G+ V++ + V +++ S + +G G ++ Sbjct: 384 RDGKSIISAWNDGKIRAFAPETGRLMYVINNAHRIG-VTAIATTSDCKRVISGGGEGEVR 442 Query: 348 IWDI--EEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGH 521 +W I + K+ H+S+ + + + + S+D IWD+ + R + Sbjct: 443 VWQIGCQTQKLEEALKEHKSSVSCIRVKRNNEECVTASTDGTCIIWDLVRLRRNQMILAN 502 Query: 522 TGRIDVLRFTPDGRWIVSGGADSSV 596 T + + P+ I++ G D + Sbjct: 503 T-LFQCVCYHPEEFQIITSGTDRKI 526
>UNC37_CAEEL (O02482) Transcription factor unc-37 (Uncoordinated protein 37)| Length = 612 Score = 59.7 bits (143), Expect = 6e-09 Identities = 37/138 (26%), Positives = 63/138 (45%) Frame = +3 Query: 186 TLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEE 365 TL+ GGE V LW + T L L + +L+ E ++ A A G I I+DI Sbjct: 388 TLLIGGEASTVALWDLTTETKTLDLETDSQACYALAMSPDEKLLFACLADGNILIYDIHN 447 Query: 366 AKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLR 545 V T GH+ + LD G SG D +++ WD+ +++ + + ++ L Sbjct: 448 KVKVGTLPGHQDGASCLDLSKDGTKLWSGGLDNSVRCWDLAQRKEVAKHD-FASQVFSLG 506 Query: 546 FTPDGRWIVSGGADSSVK 599 P+ W+ G ++ V+ Sbjct: 507 CCPNDEWVAVGMENNYVE 524 Score = 32.3 bits (72), Expect = 1.1 Identities = 25/115 (21%), Positives = 48/115 (41%), Gaps = 11/115 (9%) Frame = +3 Query: 285 SLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDS-----------HPF 431 ++S D+S V G G +KIWD++E+ + +R ASLD Sbjct: 329 TISRDNSRVYTGG---KGCVKIWDVKESDISGATVVNRPPIASLDCLKENYIRSCKLFED 385 Query: 432 GDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 G+ G + + +WD+ + + + L +PD + + + AD ++ Sbjct: 386 GNTLLIGGEASTVALWDLTTETKTLDLETDSQACYALAMSPDEKLLFACLADGNI 440
>GBLP_CAEEL (Q21215) Guanine nucleotide-binding protein beta subunit 2-like 1| Length = 324 Score = 59.3 bits (142), Expect = 8e-09 Identities = 38/163 (23%), Positives = 78/163 (47%), Gaps = 4/163 (2%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLW-AVGKPTAVLSLSGLTSPVESLSFD 299 ++F++H DV F +R +++G D+ + LW + + ++ T V ++ F Sbjct: 104 RQFISHTKDVLSVAFSA-DNRQIVSGSRDKSIKLWNTLAQCKYTITDDCHTDWVSTVRFS 162 Query: 300 SSE---VMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNM 470 S V++ AG +K+W++ ++ GH ++ P G ASG D Sbjct: 163 PSNRDPVIVSAGWDK-VVKVWNLGNCRLKTNHIGHTGYVNTVTVSPDGSLCASGGKDGQA 221 Query: 471 KIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 +WD+ + + ++T G+ I+ + F+P+ W+ + SS+K Sbjct: 222 MLWDLNEGKHLYTLPGN-DVINAMSFSPNRYWLCA-AVGSSIK 262 Score = 53.5 bits (127), Expect = 4e-07 Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 9/96 (9%) Frame = +3 Query: 339 TIKIWDIEEA---------KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRK 491 TI +WD++ + VR+ TGH + + G F SGS D +++WD+ + Sbjct: 40 TILVWDVDSVAPVDEGPIGRPVRSLTGHNHFVSDVVISSDGQFALSGSWDKTLRLWDLNQ 99 Query: 492 KRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 + HT + + F+ D R IVSG D S+K Sbjct: 100 GVSTRQFISHTKDVLSVAFSADNRQIVSGSRDKSIK 135 Score = 53.5 bits (127), Expect = 4e-07 Identities = 41/161 (25%), Positives = 71/161 (44%), Gaps = 14/161 (8%) Frame = +3 Query: 159 AKFGKRTSRTLITGGEDQKVNLWAV-----------GKPTAVLSLSGLTSPVESLSFDSS 305 A + + T+++ D+ + +W V G+P V SL+G V + S Sbjct: 22 ATYTRNDKTTVLSSSRDKTILVWDVDSVAPVDEGPIGRP--VRSLTGHNHFVSDVVISSD 79 Query: 306 EVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWD- 482 +G+ T+++WD+ + R F H + S+ SGS D ++K+W+ Sbjct: 80 GQFALSGSWDKTLRLWDLNQGVSTRQFISHTKDVLSVAFSADNRQIVSGSRDKSIKLWNT 139 Query: 483 MRKKRCIHTYQGHTGRIDVLRFTPDGR--WIVSGGADSSVK 599 + + + T HT + +RF+P R IVS G D VK Sbjct: 140 LAQCKYTITDDCHTDWVSTVRFSPSNRDPVIVSAGWDKVVK 180 Score = 36.6 bits (83), Expect = 0.057 Identities = 25/107 (23%), Positives = 49/107 (45%), Gaps = 10/107 (9%) Frame = +3 Query: 195 TGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKV 374 +GG+D + LW + + + +L G + ++SF + + A S +IKIWD+E+ K Sbjct: 214 SGGKDGQAMLWDLNEGKHLYTLPG-NDVINAMSFSPNRYWLCAAVGS-SIKIWDLEDKKE 271 Query: 375 VR----------TFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDM 485 + + G C SL G +G +D ++++ + Sbjct: 272 IEELKPEIASSGSSRGSSPQCISLAWSQDGQTLFAGYTDNIIRVYQV 318
>GBLP_BRARE (O42248) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C) (RACK) Length = 317 Score = 59.3 bits (142), Expect = 8e-09 Identities = 39/159 (24%), Positives = 70/159 (44%), Gaps = 3/159 (1%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLW-AVGKPTAVLSLSGLTSPVESLSF- 296 + FV H DV F +R +++G D+ + LW +G + T V + F Sbjct: 99 RRFVGHTKDVLSVAFSA-DNRQIVSGSRDKTIKLWNTLGVCKYTIQDDSHTEWVSCVRFS 157 Query: 297 -DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMK 473 +SS +I + +K+W++ K+ GH ++ P G ASG D Sbjct: 158 PNSSNPIIVSCGWDKMVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAM 217 Query: 474 IWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADS 590 +WD+ + + ++T G I+ L F+P+ W+ + S Sbjct: 218 LWDLNEGKHLYTLDG-GDTINALCFSPNRYWLCAATGPS 255 Score = 49.7 bits (117), Expect = 6e-06 Identities = 37/146 (25%), Positives = 64/146 (43%), Gaps = 9/146 (6%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVL-----SLSGLTSPVESLSFDSSEVMIGAGAASGTIKIW 353 +++ D+ + +W + + +L G + V + S +G+ GT+++W Sbjct: 31 ILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLW 90 Query: 354 DIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQ--GHTG 527 D+ R F GH + S+ SGS D +K+W+ C +T Q HT Sbjct: 91 DLTTGTTTRRFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGV-CKYTIQDDSHTE 149 Query: 528 RIDVLRFTPDGR--WIVSGGADSSVK 599 + +RF+P+ IVS G D VK Sbjct: 150 WVSCVRFSPNSSNPIIVSCGWDKMVK 175 Score = 46.2 bits (108), Expect = 7e-05 Identities = 28/101 (27%), Positives = 45/101 (44%), Gaps = 5/101 (4%) Frame = +3 Query: 312 MIGAGAASGTIKIWDIEEAKV-----VRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKI 476 MI + + TI +W + + R GH + + G F SGS D +++ Sbjct: 30 MILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRL 89 Query: 477 WDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 WD+ + GHT + + F+ D R IVSG D ++K Sbjct: 90 WDLTTGTTTRRFVGHTKDVLSVAFSADNRQIVSGSRDKTIK 130 Score = 33.5 bits (75), Expect = 0.48 Identities = 25/106 (23%), Positives = 45/106 (42%), Gaps = 9/106 (8%) Frame = +3 Query: 195 TGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKV 374 +GG+D + LW + + + +L G + +L F + + A A +IKIWD+E + Sbjct: 209 SGGKDGQAMLWDLNEGKHLYTLDG-GDTINALCFSPNRYWLCA-ATGPSIKIWDLEGKII 266 Query: 375 V---------RTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDM 485 V C SL G +G +D +++W + Sbjct: 267 VDELRQDIITTNSKAEPPQCTSLAWSADGQTLFAGYTDNLIRVWQV 312
>WDR16_MOUSE (Q5F201) WD-repeat protein 16| Length = 620 Score = 59.3 bits (142), Expect = 8e-09 Identities = 40/162 (24%), Positives = 71/162 (43%), Gaps = 2/162 (1%) Frame = +3 Query: 117 KLQEFVA-HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLS 293 KL+E + H S V+C + K+ + +T D +W + + + T + + Sbjct: 452 KLEEALKEHKSSVSCIRV-KKNNEECVTASTDGTCIIWDLVRLRRNQMILANTL-FQCVC 509 Query: 294 FDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCAS-LDSHPFGDFFASGSSDTNM 470 + E I I W++ + V+R G S + +D G F +G D + Sbjct: 510 YHPEEFQIITSGTDRKIAYWEVFDGSVIRELEGSLSGSINGMDITQEGGHFVTGGHDHLV 569 Query: 471 KIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 K+WD + H GH+G I +R +P ++IVS AD ++ Sbjct: 570 KVWDYNEGEVTHVGVGHSGNIMAMRISPGNQYIVSVSADGAI 611 Score = 45.4 bits (106), Expect = 1e-04 Identities = 24/98 (24%), Positives = 40/98 (40%), Gaps = 1/98 (1%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSG-LTSPVESLSFDSSEVMIGAGAASGTIKIWDIEE 365 +IT G D+K+ W V + + L G L+ + + G +K+WD E Sbjct: 517 IITSGTDRKIAYWEVFDGSVIRELEGSLSGSINGMDITQEGGHFVTGGHDHLVKVWDYNE 576 Query: 366 AKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 +V GH N ++ P + S S+D + W Sbjct: 577 GEVTHVGVGHSGNIMAMRISPGNQYIVSVSADGAILRW 614 Score = 41.6 bits (96), Expect = 0.002 Identities = 23/72 (31%), Positives = 38/72 (52%), Gaps = 6/72 (8%) Frame = +3 Query: 390 GHRSNCASLDSHPFGDFFASGSSD-----TNMKIWDMRKKRCIHTYQGHTGRIDVLRFTP 554 GH +N + + GD+ ASG ++ +WD +K+ I H G+I+ L F+P Sbjct: 62 GHGNNVSCVTISKEGDYIASGQVTFMGFKADIILWDFKKRELIARLSLHKGKIEALAFSP 121 Query: 555 DGRWIVS-GGAD 587 + ++VS GG D Sbjct: 122 NDLYLVSLGGPD 133 Score = 32.3 bits (72), Expect = 1.1 Identities = 26/95 (27%), Positives = 45/95 (47%), Gaps = 12/95 (12%) Frame = +3 Query: 114 YKLQEFVA----HASDVTCAKFGKRTSRTLITGG-EDQKVNLWAV-------GKPTAVLS 257 +K +E +A H + F + GG +D V +W++ G P A L+ Sbjct: 98 FKKRELIARLSLHKGKIEALAFSPNDLYLVSLGGPDDGSVVVWSIAKRDAICGSPAAGLN 157 Query: 258 LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIE 362 + TS V S D E+ + AG +GTI++W+++ Sbjct: 158 VGNATSVVFSRCRD--EMFVTAG--NGTIRVWELD 188 Score = 32.0 bits (71), Expect = 1.4 Identities = 26/144 (18%), Positives = 62/144 (43%), Gaps = 3/144 (2%) Frame = +3 Query: 174 RTSRTLITGGEDQKVNLWAVGKPTAVLSL-SGLTSPVESLSFDSSEVMIGAGAASGTIKI 350 R +++I+ +D K+ +A + ++ S V +++ S I +G G +++ Sbjct: 384 RDGKSIISAWDDGKIRAFAPESGRLMYTINSAHRIGVTAIATTSDCKRIISGGGEGEVRV 443 Query: 351 WDI--EEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHT 524 W + + K+ H+S+ + + + + S+D IWD+ + R +T Sbjct: 444 WQVGCQTQKLEEALKEHKSSVSCIRVKKNNEECVTASTDGTCIIWDLVRLRRNQMILANT 503 Query: 525 GRIDVLRFTPDGRWIVSGGADSSV 596 + + P+ I++ G D + Sbjct: 504 -LFQCVCYHPEEFQIITSGTDRKI 526
>GBLP_NICPL (P93340) Guanine nucleotide-binding protein beta subunit-like| protein Length = 326 Score = 58.9 bits (141), Expect = 1e-08 Identities = 36/139 (25%), Positives = 64/139 (46%), Gaps = 4/139 (2%) Frame = +3 Query: 192 ITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWD-IEEA 368 ++G D ++ LW + T G T V S++F + I + + +I++W+ + E Sbjct: 80 LSGSWDGELRLWDLQAGTTARRFVGHTKDVLSVAFSADNRQIVSASRDKSIRLWNTLGEC 139 Query: 369 K-VVRTFTGHRS--NCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDV 539 K +++ H +C + SGS D +KIW++ + T GHTG ++ Sbjct: 140 KYIIQDGDSHSDWVSCVRFSPNNLQPTIVSGSWDRTVKIWNLTNCKLRATLAGHTGYVNT 199 Query: 540 LRFTPDGRWIVSGGADSSV 596 +PDG SGG D + Sbjct: 200 TAVSPDGSLCASGGKDGVI 218 Score = 56.2 bits (134), Expect = 7e-08 Identities = 40/163 (24%), Positives = 77/163 (47%), Gaps = 4/163 (2%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLW-AVGKPTAVLSLSGLTSP-VESLSF 296 + FV H DV F +R +++ D+ + LW +G+ ++ S V + F Sbjct: 100 RRFVGHTKDVLSVAFSA-DNRQIVSASRDKSIRLWNTLGECKYIIQDGDSHSDWVSCVRF 158 Query: 297 DSSEVM--IGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNM 470 + + I +G+ T+KIW++ K+ T GH + P G ASG D + Sbjct: 159 SPNNLQPTIVSGSWDRTVKIWNLTNCKLRATLAGHTGYVNTTAVSPDGSLCASGGKDGVI 218 Query: 471 KIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 +WD+ + + +++ + + I L F+P+ W+ + +SS+K Sbjct: 219 LLWDLAEGKKLYSLESGS-IIHSLCFSPNRYWLCA-ATESSIK 259 Score = 53.5 bits (127), Expect = 4e-07 Identities = 39/164 (23%), Positives = 70/164 (42%), Gaps = 9/164 (5%) Frame = +3 Query: 135 AHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLS-----LSGLTSPVESLSFD 299 AH VT S ++T D+ + +W++ K L+G V+ + Sbjct: 14 AHTDWVTAIATPVDNSDMIVTSSRDKSIIVWSLTKDGPQYGVPRRRLTGHGHFVQDVVLS 73 Query: 300 SSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 S + +G+ G +++WD++ R F GH + S+ S S D ++++W Sbjct: 74 SDGMFALSGSWDGELRLWDLQAGTTARRFVGHTKDVLSVAFSADNRQIVSASRDKSIRLW 133 Query: 480 DM--RKKRCIHTYQGHTGRIDVLRFTPDG--RWIVSGGADSSVK 599 + K I H+ + +RF+P+ IVSG D +VK Sbjct: 134 NTLGECKYIIQDGDSHSDWVSCVRFSPNNLQPTIVSGSWDRTVK 177 Score = 33.9 bits (76), Expect = 0.37 Identities = 30/113 (26%), Positives = 47/113 (41%), Gaps = 18/113 (15%) Frame = +3 Query: 195 TGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKV 374 +GG+D + LW + + + SL S + SL F + + A A +IKIWD+E + Sbjct: 211 SGGKDGVILLWDLAEGKKLYSLES-GSIIHSLCFSPNRYWLCA-ATESSIKIWDLESKTI 268 Query: 375 V----------------RTFTGHRS--NCASLDSHPFGDFFASGSSDTNMKIW 479 V T +G C SL G SG +D +++W Sbjct: 269 VDDLKVDLKQESEMSAEGTASGKNKVIYCTSLGWSADGSTLFSGYTDGLIRVW 321
>DIP2_YEAST (Q12220) DOM34-interacting protein 2 (U3 small nucleolar| RNA-associated protein 12) (U3 snoRNA-associated protein 12) Length = 943 Score = 58.9 bits (141), Expect = 1e-08 Identities = 40/151 (26%), Positives = 61/151 (40%) Frame = +3 Query: 147 DVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAG 326 D+ C + R L D V ++ + LSL G PV S+ MI Sbjct: 533 DILCVRVSP-DDRYLAISLLDNTVKVFFLDSMKFYLSLYGHKLPVLSIDISFDSKMIITS 591 Query: 327 AASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIH 506 +A IKIW ++ ++ H+ + ++ P F S S D +K WD K CI Sbjct: 592 SADKNIKIWGLDFGDCHKSLFAHQDSIMNVKFLPQSHNFFSCSKDAVVKYWDGEKFECIQ 651 Query: 507 TYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 H + L DG ++VS D S++ Sbjct: 652 KLYAHQSEVWALAVATDGGFVVSSSHDHSIR 682 Score = 58.2 bits (139), Expect = 2e-08 Identities = 35/137 (25%), Positives = 62/137 (45%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L G D + +W + T +L+ +G + + L FD + + +G+ I +WD+ Sbjct: 94 LAVGYADGVIKVWDLMSKTVLLNFNGHKAAITLLQFDGTGTRLISGSKDSNIIVWDLVGE 153 Query: 369 KVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLRF 548 + H+ + D+ S S D +K+WD++ +CI T+ HTG L Sbjct: 154 VGLYKLRSHKDSITGFWCQG-EDWLISTSKDGMIKLWDLKTHQCIETHIAHTGECWGLAV 212 Query: 549 TPDGRWIVSGGADSSVK 599 D +++ G DS VK Sbjct: 213 KDD--LLITTGTDSQVK 227 Score = 54.7 bits (130), Expect = 2e-07 Identities = 36/121 (29%), Positives = 62/121 (51%), Gaps = 2/121 (1%) Frame = +3 Query: 243 TAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEAKVVRTF-TGHRSNCASLD 419 T + L G + V S+ ++ A A++G++KIW+I+ K +RTF G+ C L Sbjct: 382 THTIELQGQRTDVRSIDISDDNKLL-ATASNGSLKIWNIKTHKCIRTFECGYALTCKFL- 439 Query: 420 SHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQ-GHTGRIDVLRFTPDGRWIVSGGADSSV 596 P G G+ + ++++D+ + T + H I L T DG+ +V+G AD +V Sbjct: 440 --PGGLLVILGTRNGELQLFDLASSSLLDTIEDAHDAAIWSLDLTSDGKRLVTGSADKTV 497 Query: 597 K 599 K Sbjct: 498 K 498 Score = 52.8 bits (125), Expect = 8e-07 Identities = 36/143 (25%), Positives = 59/143 (41%), Gaps = 13/143 (9%) Frame = +3 Query: 210 QKVNLWAVGKPTAVLSLSGLTSPVES------------LSFDSSEVMIGAGAASGTIKIW 353 + VN+W + V LS P S L ++ G A G IK+W Sbjct: 47 EDVNIWDIKTGDLVSKLSDGLPPGASDARGAKPAECTYLEAHKDTDLLAVGYADGVIKVW 106 Query: 354 DIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRI 533 D+ V+ F GH++ L G SGS D+N+ +WD+ + ++ + H + Sbjct: 107 DLMSKTVLLNFNGHKAAITLLQFDGTGTRLISGSKDSNIIVWDLVGEVGLYKLRSH--KD 164 Query: 534 DVLRFTPDGR-WIVSGGADSSVK 599 + F G W++S D +K Sbjct: 165 SITGFWCQGEDWLISTSKDGMIK 187 Score = 41.2 bits (95), Expect = 0.002 Identities = 34/155 (21%), Positives = 57/155 (36%), Gaps = 16/155 (10%) Frame = +3 Query: 183 RTLITGGEDQKVNLW-----------AVGKPTAVLSLSG-----LTSPVESLSFDSSEVM 314 + L+TG D+ V W K VL L LT + + + Sbjct: 486 KRLVTGSADKTVKFWDFKVENSLVPGTKNKFLPVLKLHHDTTLELTDDILCVRVSPDDRY 545 Query: 315 IGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKK 494 + T+K++ ++ K + GH+ S+D + S+D N+KIW + Sbjct: 546 LAISLLDNTVKVFFLDSMKFYLSLYGHKLPVLSIDISFDSKMIITSSADKNIKIWGLDFG 605 Query: 495 RCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 C + H I ++F P S D+ VK Sbjct: 606 DCHKSLFAHQDSIMNVKFLPQSHNFFSCSKDAVVK 640 Score = 40.4 bits (93), Expect = 0.004 Identities = 22/101 (21%), Positives = 44/101 (43%) Frame = +3 Query: 180 SRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDI 359 S+ +IT D+ + +W + SL + ++ F + + +K WD Sbjct: 585 SKMIITSSADKNIKIWGLDFGDCHKSLFAHQDSIMNVKFLPQSHNFFSCSKDAVVKYWDG 644 Query: 360 EEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 E+ + ++ H+S +L G F S S D +++IW+ Sbjct: 645 EKFECIQKLYAHQSEVWALAVATDGGFVVSSSHDHSIRIWE 685
>GBLP_ORENI (O42249) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C) (RACK) Length = 317 Score = 58.9 bits (141), Expect = 1e-08 Identities = 41/160 (25%), Positives = 71/160 (44%), Gaps = 4/160 (2%) Frame = +3 Query: 123 QEFVAHASDVTCAKFGKRTSRTLITGGEDQKVNLW-AVGKPTAVLSLSGLTSPVESLSF- 296 + FV H DV F +R +++G D+ + LW +G + G T V + F Sbjct: 99 RRFVGHTKDVLSVAFSA-DNRQIVSGSRDKTIKLWNTLGVCKYTIQDEGHTEWVSCVRFS 157 Query: 297 -DSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMK 473 +SS +I + +K+W++ K+ GH ++ P G ASG D Sbjct: 158 PNSSNPIIVSCGWDKMVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAM 217 Query: 474 IWDMRKKRCIHTYQGHTGR-IDVLRFTPDGRWIVSGGADS 590 +WD+ + + H Y +G I+ L F+P+ W+ + S Sbjct: 218 LWDLNEGK--HLYTLDSGDVINALCFSPNRYWLCAATGPS 255 Score = 54.7 bits (130), Expect = 2e-07 Identities = 40/146 (27%), Positives = 65/146 (44%), Gaps = 9/146 (6%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVL-----SLSGLTSPVESLSFDSSEVMIGAGAASGTIKIW 353 +++ D+ + +W + + SL G + V + S +GA GT+++W Sbjct: 31 ILSASRDKSIIMWKLTRDETNYGIPQRSLKGHSHFVSDVVISSDGQFALSGAWDGTLRLW 90 Query: 354 DIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQ--GHTG 527 D+ R F GH + S+ SGS D +K+W+ C +T Q GHT Sbjct: 91 DLTTGLTTRRFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGV-CKYTIQDEGHTE 149 Query: 528 RIDVLRFTPDGR--WIVSGGADSSVK 599 + +RF+P+ IVS G D VK Sbjct: 150 WVSCVRFSPNSSNPIIVSCGWDKMVK 175 Score = 31.2 bits (69), Expect = 2.4 Identities = 25/106 (23%), Positives = 47/106 (44%), Gaps = 9/106 (8%) Frame = +3 Query: 195 TGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIE---- 362 +GG+D + LW + + + +L + +L F + + A A +IKIWD+E Sbjct: 209 SGGKDGQAMLWDLNEGKHLYTLDS-GDVINALCFSPNRYWLCA-ATGPSIKIWDLEGKII 266 Query: 363 ----EAKVVRTFT-GHRSNCASLDSHPFGDFFASGSSDTNMKIWDM 485 +V+ T + C SL G +G +D +++W + Sbjct: 267 VDELRQEVISTNSKAEPPQCTSLAWSADGQTLFAGYTDNLIRVWQV 312
>SRW1_SCHPO (O13286) WD-repeat-containing protein srw1 (Suppressor of rad/wee1)| Length = 556 Score = 58.5 bits (140), Expect = 1e-08 Identities = 38/159 (23%), Positives = 72/159 (45%), Gaps = 4/159 (2%) Frame = +3 Query: 135 AHASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVM 314 AH +V C L +GG D + +W + + S + V+++++ + Sbjct: 372 AHRQEV-CGLEWNSNENLLASGGNDNALMVWDKFEEKPLYSFHNHIAAVKAITWSPHQRG 430 Query: 315 I---GAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFAS-GSSDTNMKIWD 482 I G G A TIK+W+ + ++ C L S +F ++ G + + +W+ Sbjct: 431 ILASGGGTADRTIKLWNTQRGSMLHNIDTGSQVCNLLWSKQTNEFISTHGFMENEVALWN 490 Query: 483 MRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSVK 599 + T +GHT R+ L +P+G IV+G AD +++ Sbjct: 491 YPSVSRVGTLKGHTDRVLYLAMSPNGENIVTGAADETLR 529 Score = 51.6 bits (122), Expect = 2e-06 Identities = 32/141 (22%), Positives = 65/141 (46%), Gaps = 4/141 (2%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIEEA 368 L G + V +W ++SG T V +LS++ ++ +G I D+ Sbjct: 306 LAVGTHNGSVEIWDAATCKKTRTMSGHTERVGALSWNDH--VLSSGGRDNHILHRDVRAP 363 Query: 369 K-VVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLR 545 + R T HR L+ + + ASG +D + +WD +++ ++++ H + + Sbjct: 364 EHYFRVLTAHRQEVCGLEWNSNENLLASGGNDNALMVWDKFEEKPLYSFHNHIAAVKAIT 423 Query: 546 FTPDGRWIVSGG---ADSSVK 599 ++P R I++ G AD ++K Sbjct: 424 WSPHQRGILASGGGTADRTIK 444 Score = 36.6 bits (83), Expect = 0.057 Identities = 26/133 (19%), Positives = 52/133 (39%), Gaps = 3/133 (2%) Frame = +3 Query: 120 LQEFVAHASDVTCAKFGKRTSRTLITGG--EDQKVNLWAVGKPTAVLSLSGLTSPVESL- 290 L F H + V + L +GG D+ + LW + + + ++ + L Sbjct: 409 LYSFHNHIAAVKAITWSPHQRGILASGGGTADRTIKLWNTQRGSMLHNIDTGSQVCNLLW 468 Query: 291 SFDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNM 470 S ++E + G + +W+ V T GH L P G+ +G++D + Sbjct: 469 SKQTNEFISTHGFMENEVALWNYPSVSRVGTLKGHTDRVLYLAMSPNGENIVTGAADETL 528 Query: 471 KIWDMRKKRCIHT 509 + W + + H+ Sbjct: 529 RFWKLFDSKSKHS 541
>WDR16_MACFA (Q95JL5) WD-repeat protein 16| Length = 571 Score = 58.5 bits (140), Expect = 1e-08 Identities = 40/162 (24%), Positives = 72/162 (44%), Gaps = 2/162 (1%) Frame = +3 Query: 117 KLQEFVA-HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSPVESLS 293 KL+E + H S V+C + K+ + +T D +W + + + T + + Sbjct: 403 KLEEALKEHKSSVSCIRV-KKNNEECVTASTDGTCIIWDLVRLRRNQMILANTL-FQCVC 460 Query: 294 FDSSEVMIGAGAASGTIKIWDIEEAKVVRTFTGHRSNCAS-LDSHPFGDFFASGSSDTNM 470 + E I I W++ + V+R G S + +D G F +G +D + Sbjct: 461 YHPEEFQIITSGTDRKIAYWEVFDGTVIRELEGSLSGSINGMDITQEGVHFVTGGNDHLV 520 Query: 471 KIWDMRKKRCIHTYQGHTGRIDVLRFTPDGRWIVSGGADSSV 596 K+WD + H GH+G I +R +P ++IVS AD ++ Sbjct: 521 KVWDYNEGEVTHVGVGHSGNITRIRISPGNQYIVSVSADGAI 562 Score = 49.3 bits (116), Expect = 8e-06 Identities = 26/98 (26%), Positives = 40/98 (40%), Gaps = 1/98 (1%) Frame = +3 Query: 189 LITGGEDQKVNLWAVGKPTAVLSLSG-LTSPVESLSFDSSEVMIGAGAASGTIKIWDIEE 365 +IT G D+K+ W V T + L G L+ + + V G +K+WD E Sbjct: 468 IITSGTDRKIAYWEVFDGTVIRELEGSLSGSINGMDITQEGVHFVTGGNDHLVKVWDYNE 527 Query: 366 AKVVRTFTGHRSNCASLDSHPFGDFFASGSSDTNMKIW 479 +V GH N + P + S S+D + W Sbjct: 528 GEVTHVGVGHSGNITRIRISPGNQYIVSVSADGAILRW 565 Score = 38.1 bits (87), Expect = 0.020 Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 6/72 (8%) Frame = +3 Query: 390 GHRSNCASLDSHPFGDFFASGSSD-----TNMKIWDMRKKRCIHTYQGHTGRIDVLRFTP 554 GH +N + L G + ASG ++ +WD +K+ + H G+I+ L F+P Sbjct: 62 GHGNNVSCLAISRSGRYIASGQVTFMGFKADIILWDYKKRELLARLSLHKGKIEALAFSP 121 Query: 555 DGRWIVS-GGAD 587 + ++VS GG D Sbjct: 122 NDLYLVSLGGPD 133 Score = 31.6 bits (70), Expect = 1.8 Identities = 25/95 (26%), Positives = 45/95 (47%), Gaps = 12/95 (12%) Frame = +3 Query: 114 YKLQEFVA----HASDVTCAKFGKRTSRTLITGG-EDQKVNLWAV-------GKPTAVLS 257 YK +E +A H + F + GG +D V +W++ G P A L+ Sbjct: 98 YKKRELLARLSLHKGKIEALAFSPNDLYLVSLGGPDDGSVVVWSIAKRDAICGSPAAGLN 157 Query: 258 LSGLTSPVESLSFDSSEVMIGAGAASGTIKIWDIE 362 + T+ + S D E+ + AG +GTI++W+++ Sbjct: 158 VGNATNVIFSRCRD--EMFVTAG--NGTIRVWELD 188
>CSTF1_PONPY (Q5R8K2) Cleavage stimulation factor, 50 kDa subunit (CSTF 50 kDa| subunit) (CF-1 50 kDa subunit) (CstF-50) Length = 431 Score = 58.5 bits (140), Expect = 1e-08 Identities = 43/161 (26%), Positives = 75/161 (46%), Gaps = 7/161 (4%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSP--VESLSFDSSEV 311 H +VTC F T + L +G D + L+ KP+A + + + S+SF S Sbjct: 172 HVDEVTCLAFHP-TEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGD 230 Query: 312 MIGAGAASGTIKIWDIEEAKVVRTFTG---HRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 I G T++++DI + + H S++ + + + +GS D +K+WD Sbjct: 231 FILVGTQHPTLRLYDINTFQCFVSCNPQDQHADAICSVNYNSSANMYVTGSKDGCIKLWD 290 Query: 483 MRKKRCIHTYQ-GHTG-RIDVLRFTPDGRWIVSGGADSSVK 599 RCI T++ H G + F+ + ++I+S G DS K Sbjct: 291 GVSNRCITTFEKAHDGAEVCSAIFSKNSKYILSSGKDSVAK 331 Score = 36.2 bits (82), Expect = 0.074 Identities = 31/127 (24%), Positives = 48/127 (37%), Gaps = 26/127 (20%) Frame = +3 Query: 276 PVESLSFDSSEVMIGAGAASGTIKIWD-----------------------IEEAKVVRTF 386 P ++ +I G+A +IKI D +E V+RT Sbjct: 110 PCRVATYSRDGQLIATGSADASIKILDTERMLAKSAMPIEVMMNETAQQNMENHPVIRTL 169 Query: 387 TGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLR---FTPD 557 H L HP ASGS D +K++D K ++ + ++LR F P Sbjct: 170 YDHVDEVTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFK-YIQEAEMLRSISFHPS 228 Query: 558 GRWIVSG 578 G +I+ G Sbjct: 229 GDFILVG 235
>CSTF1_HUMAN (Q05048) Cleavage stimulation factor, 50 kDa subunit (CSTF 50 kDa| subunit) (CF-1 50 kDa subunit) (CstF-50) Length = 431 Score = 58.5 bits (140), Expect = 1e-08 Identities = 43/161 (26%), Positives = 75/161 (46%), Gaps = 7/161 (4%) Frame = +3 Query: 138 HASDVTCAKFGKRTSRTLITGGEDQKVNLWAVGKPTAVLSLSGLTSP--VESLSFDSSEV 311 H +VTC F T + L +G D + L+ KP+A + + + S+SF S Sbjct: 172 HVDEVTCLAFHP-TEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGD 230 Query: 312 MIGAGAASGTIKIWDIEEAKVVRTFTG---HRSNCASLDSHPFGDFFASGSSDTNMKIWD 482 I G T++++DI + + H S++ + + + +GS D +K+WD Sbjct: 231 FILVGTQHPTLRLYDINTFQCFVSCNPQDQHTDAICSVNYNSSANMYVTGSKDGCIKLWD 290 Query: 483 MRKKRCIHTYQ-GHTG-RIDVLRFTPDGRWIVSGGADSSVK 599 RCI T++ H G + F+ + ++I+S G DS K Sbjct: 291 GVSNRCITTFEKAHDGAEVCSAIFSKNSKYILSSGKDSVAK 331 Score = 36.2 bits (82), Expect = 0.074 Identities = 31/127 (24%), Positives = 48/127 (37%), Gaps = 26/127 (20%) Frame = +3 Query: 276 PVESLSFDSSEVMIGAGAASGTIKIWD-----------------------IEEAKVVRTF 386 P ++ +I G+A +IKI D +E V+RT Sbjct: 110 PCRVATYSRDGQLIATGSADASIKILDTERMLAKSAMPIEVMMNETAQQNMENHPVIRTL 169 Query: 387 TGHRSNCASLDSHPFGDFFASGSSDTNMKIWDMRKKRCIHTYQGHTGRIDVLR---FTPD 557 H L HP ASGS D +K++D K ++ + ++LR F P Sbjct: 170 YDHVDEVTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFK-YIQEAEMLRSISFHPS 228 Query: 558 GRWIVSG 578 G +I+ G Sbjct: 229 GDFILVG 235 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 91,839,391 Number of Sequences: 219361 Number of extensions: 1999226 Number of successful extensions: 9174 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 5969 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 8018 length of database: 80,573,946 effective HSP length: 107 effective length of database: 57,102,319 effective search space used: 5253413348 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
