>NTCP2_CRIGR (Q60414) Ileal sodium/bile acid cotransporter (Ileal Na(+)/bile|
           acid cotransporter) (Na(+)-dependent ileal bile acid
           transporter) (Ileal sodium-dependent bile acid
           transporter) (ISBT) (IBAT) (Apical sodium-dependent bile
           acid transporter) (AS
          Length = 348

 Score = 79.3 bits (194), Expect = 7e-15
 Identities = 41/108 (37%), Positives = 63/108 (58%), Gaps = 7/108 (6%)
 Frame = +1

Query: 250 LRNPWTVGVGFLAQYLIKPMLGYAIALTLKLSAPLATGLILVSCCPGGQASNVATYISKG 429
           LR PW + VGFL Q+ I P+ G+ +++   +    A  +++  CCPGG ASN+  Y   G
Sbjct: 62  LRRPWGIVVGFLCQFGIMPLTGFVLSVAFGILPVQAVVVLIQGCCPGGTASNILAYWVDG 121

Query: 430 NVALSVLMTTCSTIGAIAMTPL----LTKLLAGQ---LVPVDAAGLAI 552
           ++ LSV MTTCST+ A+ M PL     TK+       ++P D+ G ++
Sbjct: 122 DMDLSVSMTTCSTLLALGMMPLCLFIYTKMWVDSGTIVIPYDSIGTSL 169

>NTCP2_RABIT (Q28727) Ileal sodium/bile acid cotransporter (Ileal Na(+)/bile|
           acid cotransporter) (Na(+) dependent ileal bile acid
           transporter) (Ileal sodium-dependent bile acid
           transporter) (ISBT) (IBAT) (Apical sodium dependent bile
           acid transporter) (AS
          Length = 347

 Score = 79.3 bits (194), Expect = 7e-15
 Identities = 35/82 (42%), Positives = 53/82 (64%)
 Frame = +1

Query: 250 LRNPWTVGVGFLAQYLIKPMLGYAIALTLKLSAPLATGLILVSCCPGGQASNVATYISKG 429
           +R PW + +GFL Q+ I P+ G+ +A+   +    A  ++++ CCPGG ASN+  Y   G
Sbjct: 63  IRRPWGIFIGFLCQFGIMPLTGFVLAVAFGIMPIQAVVVLIMGCCPGGTASNILAYWVDG 122

Query: 430 NVALSVLMTTCSTIGAIAMTPL 495
           ++ LSV MTTCST+ A+ M PL
Sbjct: 123 DMDLSVSMTTCSTLLALGMMPL 144

>NTCP2_HUMAN (Q12908) Ileal sodium/bile acid cotransporter (Ileal Na(+)/bile|
           acid cotransporter) (Na(+)-dependent ileal bile acid
           transporter) (Ileal sodium-dependent bile acid
           transporter) (ISBT) (IBAT) (Apical sodium-dependent bile
           acid transporter) (AS
          Length = 348

 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 39/101 (38%), Positives = 61/101 (60%)
 Frame = +1

Query: 250 LRNPWTVGVGFLAQYLIKPMLGYAIALTLKLSAPLATGLILVSCCPGGQASNVATYISKG 429
           ++ PW + VGFL Q+ I P+ G+ +++   +    A  ++++ CCPGG ASN+  Y   G
Sbjct: 62  IKRPWGICVGFLCQFGIMPLTGFILSVAFDILPLQAVVVLIIGCCPGGTASNILAYWVDG 121

Query: 430 NVALSVLMTTCSTIGAIAMTPLLTKLLAGQLVPVDAAGLAI 552
           ++ LSV MTTCST+ A+ M PL   LL    + VD+  + I
Sbjct: 122 DMDLSVSMTTCSTLLALGMMPLC--LLIYTKMWVDSGSIVI 160

>NTCP2_RAT (Q62633) Ileal sodium/bile acid cotransporter (Ileal Na(+)/bile|
           acid cotransporter) (Na(+)-dependent ileal bile acid
           transporter) (Ileal sodium-dependent bile acid
           transporter) (ISBT) (IBAT) (Apical sodium-dependent bile
           acid transporter) (ASBT
          Length = 348

 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 38/108 (35%), Positives = 64/108 (59%), Gaps = 7/108 (6%)
 Frame = +1

Query: 250 LRNPWTVGVGFLAQYLIKPMLGYAIALTLKLSAPLATGLILVSCCPGGQASNVATYISKG 429
           ++ PW + VGFL Q+ I P+ G+ +++   +    A  ++++ CCPGG  SN+  Y   G
Sbjct: 62  IKRPWGIFVGFLCQFGIMPLTGFILSVASGILPVQAVVVLIMGCCPGGTGSNILAYWIDG 121

Query: 430 NVALSVLMTTCSTIGAIAMTPL----LTKLLAGQ---LVPVDAAGLAI 552
           ++ LSV MTTCST+ A+ M PL     TK+       ++P D+ G+++
Sbjct: 122 DMDLSVSMTTCSTLLALGMMPLCLFIYTKMWVDSGTIVIPYDSIGISL 169

>NTCP2_MOUSE (P70172) Ileal sodium/bile acid cotransporter (Ileal Na(+)/bile|
           acid cotransporter) (Na(+)-dependent ileal bile acid
           transporter) (Ileal sodium-dependent bile acid
           transporter) (ISBT) (IBAT) (Apical sodium-dependent bile
           acid transporter) (AS
          Length = 348

 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 38/108 (35%), Positives = 64/108 (59%), Gaps = 7/108 (6%)
 Frame = +1

Query: 250 LRNPWTVGVGFLAQYLIKPMLGYAIALTLKLSAPLATGLILVSCCPGGQASNVATYISKG 429
           ++ PW + VGFL Q+ I P+ G+ +++   +    A  ++++ CCPGG  SN+  Y   G
Sbjct: 62  IKRPWGIFVGFLCQFGIMPLTGFILSVASGILPVQAVVVLIMGCCPGGTGSNILAYWIDG 121

Query: 430 NVALSVLMTTCSTIGAIAMTPL----LTKLLAGQ---LVPVDAAGLAI 552
           ++ LSV MTTCST+ A+ M PL     TK+       ++P D+ G+++
Sbjct: 122 DMDLSVSMTTCSTLLALGMMPLCLFVYTKMWVDSGTIVIPYDSIGISL 169

>NTCP_HUMAN (Q14973) Sodium/bile acid cotransporter (Na(+)/bile acid|
           cotransporter) (Na(+)/taurocholate transport protein)
           (Sodium/taurocholate cotransporting polypeptide) (Solute
           carrier family 10 member 1)
          Length = 349

 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 31/83 (37%), Positives = 47/83 (56%)
 Frame = +1

Query: 250 LRNPWTVGVGFLAQYLIKPMLGYAIALTLKLSAPLATGLILVSCCPGGQASNVATYISKG 429
           L  P  + +  +AQY I P+  + +    +L    A  +++  C PGG  SNV +   KG
Sbjct: 55  LWKPKGLAIALVAQYGIMPLTAFVLGKVFRLKNIEALAILVCGCSPGGNLSNVFSLAMKG 114

Query: 430 NVALSVLMTTCSTIGAIAMTPLL 498
           ++ LS++MTTCST  A+ M PLL
Sbjct: 115 DMNLSIVMTTCSTFCALGMMPLL 137

>NTCP_RAT (P26435) Sodium/bile acid cotransporter (Na(+)/bile acid|
           cotransporter) (Na(+)/taurocholate transport protein)
           (Sodium/taurocholate cotransporting polypeptide) (Solute
           carrier family 10 member 1)
          Length = 362

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 32/83 (38%), Positives = 47/83 (56%)
 Frame = +1

Query: 250 LRNPWTVGVGFLAQYLIKPMLGYAIALTLKLSAPLATGLILVSCCPGGQASNVATYISKG 429
           L  P  V V  +AQ+ I P+  + +     LS   A  +++  C PGG  SN+ T   KG
Sbjct: 55  LWKPKGVIVALVAQFGIMPLAAFLLGKIFHLSNIEALAILICGCSPGGNLSNLFTLAMKG 114

Query: 430 NVALSVLMTTCSTIGAIAMTPLL 498
           ++ LS++MTTCS+  A+ M PLL
Sbjct: 115 DMNLSIVMTTCSSFSALGMMPLL 137

>NTCP_MOUSE (O08705) Sodium/bile acid cotransporter (Na(+)/bile acid|
           cotransporter) (Na(+)/taurocholate transport protein)
           (Sodium/taurocholate cotransporting polypeptide) (Solute
           carrier family 10 member 1)
          Length = 362

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 30/80 (37%), Positives = 47/80 (58%)
 Frame = +1

Query: 259 PWTVGVGFLAQYLIKPMLGYAIALTLKLSAPLATGLILVSCCPGGQASNVATYISKGNVA 438
           P  V +  +AQY I P+  + +     L++  A  +++  C PGG  SN+ T   KG++ 
Sbjct: 58  PKGVIIAIVAQYGIMPLSAFLLGKVFHLTSIEALAILICGCSPGGNLSNLFTLAMKGDMN 117

Query: 439 LSVLMTTCSTIGAIAMTPLL 498
           LS++MTTCS+  A+ M PLL
Sbjct: 118 LSIVMTTCSSFTALGMMPLL 137

>P3_MOUSE (P21129) P3 protein (Solute carrier family 10 member 3)|
          Length = 473

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 29/88 (32%), Positives = 46/88 (52%)
 Frame = +1

Query: 232 EDFRRCLRNPWTVGVGFLAQYLIKPMLGYAIALTLKLSAPLATGLILVSCCPGGQASNVA 411
           E  +  L++P  + +G L Q+L+ P   + +A    L   LA GLI+    PGG  S + 
Sbjct: 210 EVLKELLQSPQPMLLGLLGQFLVMPFYAFLMAKVFMLPKALALGLIITCSSPGGGGSYLF 269

Query: 412 TYISKGNVALSVLMTTCSTIGAIAMTPL 495
           + +  G+V L++ MT  ST+ A    PL
Sbjct: 270 SLLLGGDVTLAISMTFISTVAATGFLPL 297

>P3_HUMAN (P09131) P3 protein (Solute carrier family 10 member 3)|
          Length = 477

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 28/88 (31%), Positives = 47/88 (53%)
 Frame = +1

Query: 232 EDFRRCLRNPWTVGVGFLAQYLIKPMLGYAIALTLKLSAPLATGLILVSCCPGGQASNVA 411
           E  +  +++P  + +G L Q+L+ P+  + +A    L   LA GLI+    PGG  S + 
Sbjct: 214 EVLKGLMQSPQPMLLGLLGQFLVMPLYAFLMAKVFMLPKALALGLIITCSSPGGGGSYLF 273

Query: 412 TYISKGNVALSVLMTTCSTIGAIAMTPL 495
           + +  G+V L++ MT  ST+ A    PL
Sbjct: 274 SLLLGGDVTLAISMTFLSTVAATGFLPL 301

>Y2026_PSEAE (P39879) Hypothetical protein PA2026|
          Length = 333

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 26/82 (31%), Positives = 48/82 (58%), Gaps = 3/82 (3%)
 Frame = +1

Query: 280 FLAQYLIKPMLGYAI--ALTLKLSAPLATGLILVSCCPGGQASNVA-TYISKGNVALSVL 450
           F   +++ P+LG A+  AL+  ++  L  G++ +   P    S++A T +++GNV  +V 
Sbjct: 73  FACTFVMFPLLGLALKPALSPMVTPELYLGILFLCALPATVQSSIAFTSLARGNVPAAVC 132

Query: 451 MTTCSTIGAIAMTPLLTKLLAG 516
             + S++  + +TPLL KLL G
Sbjct: 133 SASVSSLLGVFLTPLLVKLLLG 154

>YBAS_BACSU (P55190) Hypothetical protein ybaS|
          Length = 283

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 28/106 (26%), Positives = 47/106 (44%), Gaps = 1/106 (0%)
 Frame = +1

Query: 232 EDFRRCLRNPWTVGVGFLAQYLIKPMLGYAIALTLKLSAPLA-TGLILVSCCPGGQASNV 408
           +  R  L +P  + +     ++  P+  +     +    PL  TGL L    P G  S +
Sbjct: 21  QSLRHALSHPLPMILALFVLHIFMPLFAWGSGHLIFKGDPLTITGLTLAVVIPTGITSLI 80

Query: 409 ATYISKGNVALSVLMTTCSTIGAIAMTPLLTKLLAGQLVPVDAAGL 546
              + KGNV L++ +    T+ +  + PL   LLAG  V +D  G+
Sbjct: 81  WAAMYKGNVGLTLSIILVDTVLSPLIVPLSLSLLAGAQVHMDVWGM 126

>FA5_PIG (Q9GLP1) Coagulation factor V precursor (Activated protein C|
           cofactor) [Contains: Coagulation factor V heavy chain;
           Coagulation factor V light chain]
          Length = 2258

 Score = 33.9 bits (76), Expect = 0.33
 Identities = 21/47 (44%), Positives = 27/47 (57%), Gaps = 2/47 (4%)
 Frame = +3

Query: 33  PASERAY-WSKPVRENS*ATHHSFPCLGHIRYSYWHL-QAVNGHLVG 167
           P  E  Y W+  + E+S  TH+  PCL HI YSY +L Q  N  L+G
Sbjct: 144 PGQEYTYEWN--ISEDSGPTHNDPPCLTHIYYSYENLIQDFNSGLIG 188

>RUMA_BORPE (Q7VXM6) 23S rRNA (uracil-5-)-methyltransferase rumA (EC 2.1.1.-)|
           (23S rRNA(M-5-U1939)-methyltransferase)
          Length = 466

 Score = 33.5 bits (75), Expect = 0.43
 Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 4/64 (6%)
 Frame = +1

Query: 262 WTVGVGFLAQYLIKPML--GYAIALTLKLSAP--LATGLILVSCCPGGQASNVATYISKG 429
           W  G+G+  + LI P      A+A  L L AP      ++ VSC PG  A + A  + +G
Sbjct: 350 WLRGLGYFDRMLIDPPREGAQAVAQALSLLAPGERPRRIVYVSCSPGTLARDAAIMVHEG 409

Query: 430 NVAL 441
             AL
Sbjct: 410 GYAL 413

>FA5_BOVIN (Q28107) Coagulation factor V precursor (Activated protein C|
           cofactor) [Contains: Coagulation factor V heavy chain;
           Coagulation factor V light chain]
          Length = 2211

 Score = 30.8 bits (68), Expect = 2.8
 Identities = 20/47 (42%), Positives = 25/47 (53%), Gaps = 2/47 (4%)
 Frame = +3

Query: 33  PASERAY-WSKPVRENS*ATHHSFPCLGHIRYSYWHL-QAVNGHLVG 167
           P  E  Y W   + E+S  TH   PCL HI YSY +L +  N  L+G
Sbjct: 144 PGQEYTYEWI--ISEHSGPTHDDPPCLTHIYYSYVNLVEDFNSGLIG 188

>FA5_HUMAN (P12259) Coagulation factor V precursor (Activated protein C|
           cofactor) [Contains: Coagulation factor V heavy chain;
           Coagulation factor V light chain]
          Length = 2224

 Score = 30.8 bits (68), Expect = 2.8
 Identities = 20/47 (42%), Positives = 26/47 (55%), Gaps = 2/47 (4%)
 Frame = +3

Query: 33  PASERAY-WSKPVRENS*ATHHSFPCLGHIRYSYWHL-QAVNGHLVG 167
           P  E  Y WS  + E+S  TH   PCL HI YS+ +L +  N  L+G
Sbjct: 144 PGREYTYEWS--ISEDSGPTHDDPPCLTHIYYSHENLIEDFNSGLIG 188

>MNTH2_PSEAE (Q9RPF2) Manganese transport protein mntH2|
          Length = 438

 Score = 30.4 bits (67), Expect = 3.6
 Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 7/79 (8%)
 Frame = +1

Query: 307 MLGYAIALTLKLSAPLATGLILVSCCPGGQASNVATYISKGN-------VALSVLMTTCS 465
           ++G AIAL L    PLA G +L      G A  V   I +G        VAL  L+  C 
Sbjct: 127 VIGTAIALKLLFGLPLAWGALLCV----GDALLVLVLIGRGQRPLEAFVVALLTLIFACF 182

Query: 466 TIGAIAMTPLLTKLLAGQL 522
            +  +   P L ++L G L
Sbjct: 183 AVQLLLSRPELGEVLQGFL 201

>YFEH_ECOLI (P39836) Hypothetical protein yfeH|
          Length = 332

 Score = 29.6 bits (65), Expect = 6.1
 Identities = 21/76 (27%), Positives = 40/76 (52%), Gaps = 3/76 (3%)
 Frame = +1

Query: 292 YLIKPMLGYAIAL--TLKLSAPLATGLILVSCCPGGQASNVA-TYISKGNVALSVLMTTC 462
           +++ P+LG   A    + +   L +G + +   P    S +A T ++ GNVA +V   + 
Sbjct: 76  FVLFPILGVLFAWWKPVNVDPMLYSGFLYLCILPATVQSAIAFTSMAGGNVAAAVCSASA 135

Query: 463 STIGAIAMTPLLTKLL 510
           S++  I ++PLL  L+
Sbjct: 136 SSLLGIFLSPLLVGLV 151

>MATK_CICAR (Q5YK05) Maturase K (Intron maturase)|
          Length = 509

 Score = 29.6 bits (65), Expect = 6.1
 Identities = 15/67 (22%), Positives = 34/67 (50%)
 Frame = -2

Query: 266 VHGFLKHLLKSSNVNVSPIDSIRNPRPRVKRSVSNQVTIDGL*MPITVPNMTQTGKRVVS 87
           V   +  + + +++ +S  DS +NP     ++ ++Q+  +G  + + +P   Q+G  +  
Sbjct: 57  VKRLISRMYQQNHLIISANDSNKNPFWGYNKNFNSQIISEGFAIVVEIPFFLQSGSSLKE 116

Query: 86  SSTIFSY 66
           S  I SY
Sbjct: 117 SEIIKSY 123

>MCP_HUMAN (P15529) Membrane cofactor protein precursor (Trophoblast leukocyte|
           common antigen) (TLX) (CD46 antigen)
          Length = 392

 Score = 29.3 bits (64), Expect = 8.0
 Identities = 15/39 (38%), Positives = 19/39 (48%)
 Frame = -2

Query: 278 PTPTVHGFLKHLLKSSNVNVSPIDSIRNPRPRVKRSVSN 162
           P+ T    L H + +S+   SP  S   PRP  K  VSN
Sbjct: 289 PSSTKPPALSHSVSTSSTTKSPASSASGPRPTYKPPVSN 327


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 76,134,049
Number of Sequences: 219361
Number of extensions: 1523029
Number of successful extensions: 3897
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 3803
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3896
length of database: 80,573,946
effective HSP length: 106
effective length of database: 57,321,680
effective search space used: 4643056080
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)