ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
menu 
| Clone Name | bags8b21 |
|---|---|
| Clone Library Name | barley_pub |
>CDPK2_ORYSA (P53683) Calcium-dependent protein kinase, isoform 2 (EC 2.7.11.1)| (CDPK 2) Length = 533 Score = 303 bits (776), Expect = 2e-82 Identities = 152/189 (80%), Positives = 159/189 (84%) Frame = +3 Query: 3 GYSHQPKQAQTPPSYNNAQPPPQAEVRYTXXXXXXXXXXXXXXXXXXXXDTILGKQYEDV 182 GYSHQ K AQT PSYN+ QPPP AEVRYT DTILGK Y+DV Sbjct: 22 GYSHQTKPAQTTPSYNHPQPPPPAEVRYTPSAMNPPVVPPVVAPPKPTPDTILGKPYDDV 81 Query: 183 RSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLS 362 RSVYSLGKELGRGQFGVTYLCTEI++G+QYACKSISKRKLVSKADKEDIRREIQIMQHLS Sbjct: 82 RSVYSLGKELGRGQFGVTYLCTEIASGKQYACKSISKRKLVSKADKEDIRREIQIMQHLS 141 Query: 363 GQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCH 542 GQ NIVEF GAYEDK +VHVVMELCAGGELFDRIIAKGHYSERAAATICR VVNVVN+CH Sbjct: 142 GQQNIVEFRGAYEDKSNVHVVMELCAGGELFDRIIAKGHYSERAAATICRAVVNVVNICH 201 Query: 543 FMGVMHRDL 569 FMGVMHRDL Sbjct: 202 FMGVMHRDL 210
>CDPK2_MAIZE (P49101) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (CDPK 2)| Length = 513 Score = 276 bits (705), Expect(2) = 1e-74 Identities = 139/171 (81%), Positives = 145/171 (84%), Gaps = 2/171 (1%) Frame = +3 Query: 63 PPQ--AEVRYTXXXXXXXXXXXXXXXXXXXXDTILGKQYEDVRSVYSLGKELGRGQFGVT 236 PPQ AEVRYT DTILGKQYEDVRSVYS GKELGRGQFGVT Sbjct: 20 PPQQAAEVRYTPSATNSSAVPPVAVPPKPTADTILGKQYEDVRSVYSFGKELGRGQFGVT 79 Query: 237 YLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQPNIVEFCGAYEDKGSV 416 YLCTEI++GRQYACKSISKRKLVSKAD+EDIRREIQIMQHLSGQPNIVEF GAYEDK +V Sbjct: 80 YLCTEIASGRQYACKSISKRKLVSKADREDIRREIQIMQHLSGQPNIVEFRGAYEDKSNV 139 Query: 417 HVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMGVMHRDL 569 HVVMELCAGGELFDRIIAKGHY+ERAAATICR VVNVVN+CHFMGVMHRDL Sbjct: 140 HVVMELCAGGELFDRIIAKGHYTERAAATICRAVVNVVNICHFMGVMHRDL 190 Score = 23.9 bits (50), Expect(2) = 1e-74 Identities = 11/15 (73%), Positives = 12/15 (80%) Frame = +1 Query: 1 MAILTNQNRLKHLLV 45 MAILT Q+R KHL V Sbjct: 3 MAILTRQSRRKHLRV 17
>CDPK_DAUCA (P28582) Calcium-dependent protein kinase (EC 2.7.11.1) (CDPK)| Length = 532 Score = 233 bits (594), Expect = 3e-61 Identities = 112/140 (80%), Positives = 126/140 (90%) Frame = +3 Query: 150 DTILGKQYEDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDI 329 +TILGK +ED+R Y+LGKELGRGQFG Y CTE S+G+ YACKSI KRKLVSK DKEDI Sbjct: 67 NTILGKPFEDIRGKYTLGKELGRGQFGCVYQCTENSSGQLYACKSILKRKLVSKNDKEDI 126 Query: 330 RREIQIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATIC 509 +REIQI+QHLSGQPNIVEF G +ED+ SVH+VMELCAGGELFDRIIA+GHYSERAAATIC Sbjct: 127 KREIQILQHLSGQPNIVEFKGVFEDRQSVHLVMELCAGGELFDRIIAQGHYSERAAATIC 186 Query: 510 RGVVNVVNVCHFMGVMHRDL 569 R +VNVV+VCHFMGVMHRDL Sbjct: 187 RQIVNVVHVCHFMGVMHRDL 206
>CDPK3_ORYSA (P53684) Calcium-dependent protein kinase, isoform 11 (EC 2.7.11.1)| (CDPK 11) Length = 542 Score = 187 bits (474), Expect = 2e-47 Identities = 87/138 (63%), Positives = 110/138 (79%) Frame = +3 Query: 156 ILGKQYEDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRR 335 +LG++ D+R Y +G++LG+GQFG TYLCTEI+TG +YACK+I KRKL++K D ED+RR Sbjct: 67 VLGRKTADLREHYIIGRKLGQGQFGTTYLCTEINTGCEYACKTIPKRKLITKEDVEDVRR 126 Query: 336 EIQIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRG 515 EIQIM HLSG N+V YED +VH+VMELCAGGELFDRI KGHYSER AA + R Sbjct: 127 EIQIMHHLSGHKNVVAIKDVYEDGQAVHIVMELCAGGELFDRIQEKGHYSERKAAELIRI 186 Query: 516 VVNVVNVCHFMGVMHRDL 569 +V++V +CH +GVMHRDL Sbjct: 187 IVSIVAMCHSLGVMHRDL 204
>CDPK1_ARATH (Q06850) Calcium-dependent protein kinase, isoform AK1 (EC| 2.7.11.1) (CDPK) Length = 610 Score = 185 bits (469), Expect = 9e-47 Identities = 83/140 (59%), Positives = 112/140 (80%) Frame = +3 Query: 150 DTILGKQYEDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDI 329 +++L ++ E+ + YSLG++LG+GQFG T+LC E +TG+++ACKSI+KRKL++ D ED+ Sbjct: 136 ESVLQRKTENFKEFYSLGRKLGQGQFGTTFLCVEKTTGKEFACKSIAKRKLLTDEDVEDV 195 Query: 330 RREIQIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATIC 509 RREIQIM HL+G PN++ GAYED +VH+VME CAGGELFDRII +GHY+ER AA + Sbjct: 196 RREIQIMHHLAGHPNVISIKGAYEDVVAVHLVMECCAGGELFDRIIQRGHYTERKAAELT 255 Query: 510 RGVVNVVNVCHFMGVMHRDL 569 R +V VV CH +GVMHRDL Sbjct: 256 RTIVGVVEACHSLGVMHRDL 275
>CDPK1_ORYSA (P53682) Calcium-dependent protein kinase, isoform 1 (EC 2.7.11.1)| (CDPK 1) Length = 534 Score = 177 bits (448), Expect = 2e-44 Identities = 85/138 (61%), Positives = 105/138 (76%) Frame = +3 Query: 156 ILGKQYEDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRR 335 +LG + +VR +Y+LG+ELG+GQFG TYLCTEISTG QYACK+I K L +D ED+RR Sbjct: 61 VLGYKTPNVRELYTLGRELGQGQFGKTYLCTEISTGCQYACKTILKSNLRCVSDIEDVRR 120 Query: 336 EIQIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRG 515 EIQIM HLSGQ NIV YED+ +VH+VMELCAGGELF +I +GHYSER AA + + Sbjct: 121 EIQIMHHLSGQKNIVTIKDTYEDEQAVHIVMELCAGGELFSKIQKRGHYSERKAAELIKI 180 Query: 516 VVNVVNVCHFMGVMHRDL 569 +V ++ CH GVMHRDL Sbjct: 181 IVGIIETCHSHGVMHRDL 198
>CDPK_SOYBN (P28583) Calcium-dependent protein kinase SK5 (EC 2.7.11.1) (CDPK)| Length = 508 Score = 171 bits (433), Expect = 1e-42 Identities = 79/138 (57%), Positives = 104/138 (75%) Frame = +3 Query: 156 ILGKQYEDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRR 335 +L ++ +++R VY +G++LG+GQFG T+ CT ++G ++ACKSI KRKL+ K D ED+ R Sbjct: 22 VLPQRTQNIREVYEVGRKLGQGQFGTTFECTRRASGGKFACKSIPKRKLLCKEDYEDVWR 81 Query: 336 EIQIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRG 515 EIQIM HLS N+V G YED +VH+VMELC GGELFDRI+ KGHYSER AA + + Sbjct: 82 EIQIMHHLSEHANVVRIEGTYEDSTAVHLVMELCEGGELFDRIVQKGHYSERQAARLIKT 141 Query: 516 VVNVVNVCHFMGVMHRDL 569 +V VV CH +GVMHRDL Sbjct: 142 IVEVVEACHSLGVMHRDL 159
>CRK_DAUCA (P53681) CDPK-related protein kinase (EC 2.7.11.1) (PK421)| Length = 602 Score = 108 bits (271), Expect = 8e-24 Identities = 58/132 (43%), Positives = 84/132 (63%), Gaps = 4/132 (3%) Frame = +3 Query: 186 SVYSLGKELGRGQFGVTYLCTEIS---TGRQYACKSISKRKLVSKADKEDIRREIQIMQH 356 S + +G+E+GRG FG T G+ A K I K K+ + ED+RRE++I++ Sbjct: 146 SKFEVGEEVGRGHFGYTCRAKFKKGEFKGQDVAVKVIPKAKMTTAIAIEDVRREVKILRA 205 Query: 357 LSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAK-GHYSERAAATICRGVVNVVN 533 L+G N+V+F A+ED +V+VVMELC GGEL DRI+++ G Y+E A + ++NVV Sbjct: 206 LTGHNNLVQFYDAFEDHTNVYVVMELCEGGELLDRILSRGGKYTEDDAKAVMIQILNVVA 265 Query: 534 VCHFMGVMHRDL 569 CH GV+HRDL Sbjct: 266 FCHLQGVVHRDL 277
>KCC1D_MOUSE (Q8BW96) Calcium/calmodulin-dependent protein kinase type 1D (EC| 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) (mCKLiK) Length = 385 Score = 100 bits (250), Expect = 2e-21 Identities = 53/135 (39%), Positives = 82/135 (60%) Frame = +3 Query: 165 KQYEDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQ 344 KQ ED++ ++ + LG G F L E +TG+ +A K I K+ L K + I EI Sbjct: 14 KQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKAL--KGKESSIENEIA 71 Query: 345 IMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVN 524 +++ + + NIV YE +++VM+L +GGELFDRI+ KG Y+E+ A+T+ R V++ Sbjct: 72 VLRKIKHE-NIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLD 130 Query: 525 VVNVCHFMGVMHRDL 569 V H MG++HRDL Sbjct: 131 AVYYLHRMGIVHRDL 145
>KCC1D_HUMAN (Q8IU85) Calcium/calmodulin-dependent protein kinase type 1D (EC| 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) Length = 385 Score = 100 bits (250), Expect = 2e-21 Identities = 53/135 (39%), Positives = 82/135 (60%) Frame = +3 Query: 165 KQYEDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQ 344 KQ ED++ ++ + LG G F L E +TG+ +A K I K+ L K + I EI Sbjct: 14 KQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKAL--KGKESSIENEIA 71 Query: 345 IMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVN 524 +++ + + NIV YE +++VM+L +GGELFDRI+ KG Y+E+ A+T+ R V++ Sbjct: 72 VLRKIKHE-NIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLD 130 Query: 525 VVNVCHFMGVMHRDL 569 V H MG++HRDL Sbjct: 131 AVYYLHRMGIVHRDL 145
>DAPK1_HUMAN (P53355) Death-associated protein kinase 1 (EC 2.7.11.1) (DAP| kinase 1) Length = 1432 Score = 96.7 bits (239), Expect = 4e-20 Identities = 54/135 (40%), Positives = 75/135 (55%), Gaps = 3/135 (2%) Frame = +3 Query: 174 EDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSK---ADKEDIRREIQ 344 E+V Y G+ELG GQF V C E STG QYA K I KR+ S +EDI RE+ Sbjct: 7 ENVDDYYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIEREVS 66 Query: 345 IMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVN 524 I++ + PN++ YE+K V +++EL AGGELFD + K +E A + ++N Sbjct: 67 ILKEIQ-HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILN 125 Query: 525 VVNVCHFMGVMHRDL 569 V H + + H DL Sbjct: 126 GVYYLHSLQIAHFDL 140
>KCC2D_RAT (P15791) Calcium/calmodulin-dependent protein kinase type II delta| chain (EC 2.7.11.17) (CaM-kinase II delta chain) (CaM kinase II delta subunit) (CaMK-II delta subunit) Length = 533 Score = 95.5 bits (236), Expect = 9e-20 Identities = 51/126 (40%), Positives = 78/126 (61%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y L +ELG+G F V C +I TG++YA K I+ +KL S D + + RE +I + L P Sbjct: 14 YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKL-SARDHQKLEREARICRLLK-HP 71 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NIV + ++G ++V +L GGELF+ I+A+ +YSE A+ + ++ VN CH G Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNG 131 Query: 552 VMHRDL 569 ++HRDL Sbjct: 132 IVHRDL 137
>MYLK_DICDI (P25323) Myosin light chain kinase (EC 2.7.11.18) (MLCK)| Length = 295 Score = 95.1 bits (235), Expect = 1e-19 Identities = 48/131 (36%), Positives = 81/131 (61%) Frame = +3 Query: 177 DVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQH 356 +V +Y +ELGRG F + YL T ++YA K I+K +L K +++++ E+ I++ Sbjct: 3 EVEKIYEFKEELGRGAFSIVYLGENKQTKQRYAIKVINKSEL-GKDYEKNLKMEVDILKK 61 Query: 357 LSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNV 536 ++ PNI+ ++ +++VMEL GGELFD+I+ KG YSE AA + + +V+ V Sbjct: 62 VN-HPNIIALKELFDTPEKLYLVMELVTGGELFDKIVEKGSYSEADAANLVKKIVSAVGY 120 Query: 537 CHFMGVMHRDL 569 H + ++HRDL Sbjct: 121 LHGLNIVHRDL 131
>KCC1A_RAT (Q63450) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 374 Score = 94.4 bits (233), Expect = 2e-19 Identities = 52/135 (38%), Positives = 77/135 (57%) Frame = +3 Query: 165 KQYEDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQ 344 KQ ED+R +Y LG G F L + T + A K I+K+ L K + + EI Sbjct: 11 KQAEDIRDIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKKALEGK--EGSMENEIA 68 Query: 345 IMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVN 524 ++ H PNIV YE G ++++M+L +GGELFDRI+ KG Y+ER A+ + V++ Sbjct: 69 VL-HKIKHPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLD 127 Query: 525 VVNVCHFMGVMHRDL 569 V H +G++HRDL Sbjct: 128 AVKYLHDLGIVHRDL 142
>KCC1A_MOUSE (Q91YS8) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 374 Score = 94.4 bits (233), Expect = 2e-19 Identities = 52/135 (38%), Positives = 77/135 (57%) Frame = +3 Query: 165 KQYEDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQ 344 KQ ED+R +Y LG G F L + T + A K I+K+ L K + + EI Sbjct: 11 KQAEDIRDIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKKALEGK--EGSMENEIA 68 Query: 345 IMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVN 524 ++ H PNIV YE G ++++M+L +GGELFDRI+ KG Y+ER A+ + V++ Sbjct: 69 VL-HKIKHPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLD 127 Query: 525 VVNVCHFMGVMHRDL 569 V H +G++HRDL Sbjct: 128 AVKYLHDLGIVHRDL 142
>DAPK1_MOUSE (Q80YE7) Death-associated protein kinase 1 (EC 2.7.11.1) (DAP| kinase 1) Length = 1442 Score = 94.4 bits (233), Expect = 2e-19 Identities = 53/135 (39%), Positives = 75/135 (55%), Gaps = 3/135 (2%) Frame = +3 Query: 174 EDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSK---ADKEDIRREIQ 344 E+V Y G+ELG GQF V C E STG QYA K I KR+ S +EDI RE+ Sbjct: 7 ENVDDYYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIEREVS 66 Query: 345 IMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVN 524 I++ + PN++ YE+K V +++EL AGGELFD + K +E A + +++ Sbjct: 67 ILKEIR-HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILS 125 Query: 525 VVNVCHFMGVMHRDL 569 V H + + H DL Sbjct: 126 GVYYLHSLQIAHFDL 140
>KCC2D_HUMAN (Q13557) Calcium/calmodulin-dependent protein kinase type II delta| chain (EC 2.7.11.17) (CaM-kinase II delta chain) (CaM kinase II delta subunit) (CaMK-II delta subunit) Length = 499 Score = 94.0 bits (232), Expect = 3e-19 Identities = 51/126 (40%), Positives = 77/126 (61%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y L +ELG+G F V C +I TG+ YA K I+ +KL S D + + RE +I + L P Sbjct: 14 YQLFEELGKGAFSVVRRCMKIPTGQGYAAKIINTKKL-SARDHQKLEREARICRLLK-HP 71 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NIV + ++G ++V +L GGELF+ I+A+ +YSE A+ + ++ VN CH G Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNG 131 Query: 552 VMHRDL 569 ++HRDL Sbjct: 132 IVHRDL 137
>KCC1A_HUMAN (Q14012) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 370 Score = 93.6 bits (231), Expect = 4e-19 Identities = 52/135 (38%), Positives = 76/135 (56%) Frame = +3 Query: 165 KQYEDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQ 344 KQ ED+R +Y LG G F L + T + A K I+K L K + + EI Sbjct: 11 KQAEDIRDIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGK--EGSMENEIA 68 Query: 345 IMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVN 524 ++ H PNIV YE G ++++M+L +GGELFDRI+ KG Y+ER A+ + V++ Sbjct: 69 VL-HKIKHPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLD 127 Query: 525 VVNVCHFMGVMHRDL 569 V H +G++HRDL Sbjct: 128 AVKYLHDLGIVHRDL 142
>KCC4_RAT (P13234) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) (Calspermin) Length = 474 Score = 93.6 bits (231), Expect = 4e-19 Identities = 50/136 (36%), Positives = 76/136 (55%) Frame = +3 Query: 162 GKQYEDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREI 341 G + + + + + ELGRG + Y C + T + YA K + K DK+ +R EI Sbjct: 32 GSKRDPLSDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKKT-----VDKKIVRTEI 86 Query: 342 QIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVV 521 ++ LS PNI++ +E + +V+EL GGELFDRI+ KG+YSER AA + ++ Sbjct: 87 GVLLRLS-HPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQIL 145 Query: 522 NVVNVCHFMGVMHRDL 569 V H G++HRDL Sbjct: 146 EAVAYLHENGIVHRDL 161
>KCC4_HUMAN (Q16566) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) Length = 473 Score = 92.8 bits (229), Expect = 6e-19 Identities = 50/136 (36%), Positives = 75/136 (55%) Frame = +3 Query: 162 GKQYEDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREI 341 G + + + + ELGRG + Y C + T + YA K + K DK+ +R EI Sbjct: 36 GSNRDALSDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKKT-----VDKKIVRTEI 90 Query: 342 QIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVV 521 ++ LS PNI++ +E + +V+EL GGELFDRI+ KG+YSER AA + ++ Sbjct: 91 GVLLRLS-HPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQIL 149 Query: 522 NVVNVCHFMGVMHRDL 569 V H G++HRDL Sbjct: 150 EAVAYLHENGIVHRDL 165
>KCC2A_RAT (P11275) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 92.4 bits (228), Expect = 8e-19 Identities = 49/126 (38%), Positives = 77/126 (61%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y L +ELG+G F V C ++ G++YA K I+ +KL S D + + RE +I + L P Sbjct: 13 YQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKL-SARDHQKLEREARICRLLK-HP 70 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NIV + ++G +++ +L GGELF+ I+A+ +YSE A+ + ++ V CH MG Sbjct: 71 NIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMG 130 Query: 552 VMHRDL 569 V+HRDL Sbjct: 131 VVHRDL 136
>KCC2A_PONPY (Q5RCC4) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 92.4 bits (228), Expect = 8e-19 Identities = 49/126 (38%), Positives = 77/126 (61%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y L +ELG+G F V C ++ G++YA K I+ +KL S D + + RE +I + L P Sbjct: 13 YQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKL-SARDHQKLEREARICRLLK-HP 70 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NIV + ++G +++ +L GGELF+ I+A+ +YSE A+ + ++ V CH MG Sbjct: 71 NIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMG 130 Query: 552 VMHRDL 569 V+HRDL Sbjct: 131 VVHRDL 136
>KCC2A_HUMAN (Q9UQM7) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 92.4 bits (228), Expect = 8e-19 Identities = 49/126 (38%), Positives = 77/126 (61%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y L +ELG+G F V C ++ G++YA K I+ +KL S D + + RE +I + L P Sbjct: 13 YQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKL-SARDHQKLEREARICRLLK-HP 70 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NIV + ++G +++ +L GGELF+ I+A+ +YSE A+ + ++ V CH MG Sbjct: 71 NIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMG 130 Query: 552 VMHRDL 569 V+HRDL Sbjct: 131 VVHRDL 136
>CDPK3_PLAF7 (Q9NJU9) Calcium-dependent protein kinase 3 (EC 2.7.11.1) (PfCDPK3)| Length = 562 Score = 92.0 bits (227), Expect = 1e-18 Identities = 50/132 (37%), Positives = 78/132 (59%), Gaps = 1/132 (0%) Frame = +3 Query: 177 DVRSVYSLGKE-LGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQ 353 ++ Y+L KE LG+G +G Y T+ A K +SK+KL + R+EI IM+ Sbjct: 112 NLEDFYNLSKEPLGKGTYGCVYKATDKLLKISRAVKVVSKKKL---KNIPRFRQEIDIMK 168 Query: 354 HLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVN 533 +L PN+V+ +ED +++VMELC GGELFD+I+ KG + E A+ I + + +V+N Sbjct: 169 NLD-HPNVVKLLETFEDSNQIYLVMELCTGGELFDKIVKKGCFVETFASFIMKQIFSVLN 227 Query: 534 VCHFMGVMHRDL 569 H + HRD+ Sbjct: 228 YLHIRNICHRDI 239
>DAPK3_HUMAN (O43293) Death-associated protein kinase 3 (EC 2.7.11.1) (DAP| kinase 3) (DAP-like kinase) (Dlk) (ZIP-kinase) Length = 454 Score = 92.0 bits (227), Expect = 1e-18 Identities = 49/135 (36%), Positives = 77/135 (57%), Gaps = 3/135 (2%) Frame = +3 Query: 174 EDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSK---ADKEDIRREIQ 344 EDV Y +G+ELG GQF + C + TG++YA K I KR+L S +E+I RE+ Sbjct: 7 EDVEDHYEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVN 66 Query: 345 IMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVN 524 I++ + PNI+ +E+K V +++EL +GGELFD + K +E A + +++ Sbjct: 67 ILREIR-HPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILD 125 Query: 525 VVNVCHFMGVMHRDL 569 V+ H + H DL Sbjct: 126 GVHYLHSKRIAHFDL 140
>KCC1B_RAT (O70150) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase homolog) Length = 343 Score = 91.7 bits (226), Expect = 1e-18 Identities = 51/138 (36%), Positives = 79/138 (57%) Frame = +3 Query: 156 ILGKQYEDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRR 335 +L KQ ED+ SVY + ++LG G F L E + A K I K+ L K + + Sbjct: 3 LLKKQTEDISSVYEIREKLGSGAFSEVMLAQERGSAHLVALKCIPKKALRGK--EALVEN 60 Query: 336 EIQIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRG 515 EI +++ +S PNIV +E +++ MEL GGELFDRI+ +G Y+E+ A+ + Sbjct: 61 EIAVLRRIS-HPNIVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQ 119 Query: 516 VVNVVNVCHFMGVMHRDL 569 V+ V+ H +G++HRDL Sbjct: 120 VLGAVSYLHSLGIVHRDL 137
>KCC1B_MOUSE (Q9QYK9) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase homolog) Length = 343 Score = 91.7 bits (226), Expect = 1e-18 Identities = 51/138 (36%), Positives = 79/138 (57%) Frame = +3 Query: 156 ILGKQYEDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRR 335 +L KQ ED+ SVY + ++LG G F L E + A K I K+ L K + + Sbjct: 3 LLKKQTEDISSVYEIREKLGSGAFSEVMLAQERGSAHLVALKCIPKKALRGK--EALVEN 60 Query: 336 EIQIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRG 515 EI +++ +S PNIV +E +++ MEL GGELFDRI+ +G Y+E+ A+ + Sbjct: 61 EIAVLRRIS-HPNIVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQ 119 Query: 516 VVNVVNVCHFMGVMHRDL 569 V+ V+ H +G++HRDL Sbjct: 120 VLGAVSYLHSLGIVHRDL 137
>DAPK3_RAT (O88764) Death-associated protein kinase 3 (EC 2.7.11.1) (DAP| kinase 3) (DAP-like kinase) (Dlk) (ZIP-kinase) Length = 448 Score = 91.3 bits (225), Expect = 2e-18 Identities = 49/135 (36%), Positives = 76/135 (56%), Gaps = 3/135 (2%) Frame = +3 Query: 174 EDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSK---ADKEDIRREIQ 344 EDV Y +G+ELG GQF + C + TG +YA K I KR+L S +E+I RE+ Sbjct: 7 EDVEDHYEMGEELGSGQFAIVRKCQQKGTGMEYAAKFIKKRRLPSSRRGVSREEIEREVS 66 Query: 345 IMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVN 524 I++ + PNI+ +E+K V +++EL +GGELFD + K +E A + +++ Sbjct: 67 ILREIR-HPNIITLHDVFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILD 125 Query: 525 VVNVCHFMGVMHRDL 569 V+ H + H DL Sbjct: 126 GVHYLHSKRIAHFDL 140
>DAPK3_MOUSE (O54784) Death-associated protein kinase 3 (EC 2.7.11.1) (DAP| kinase 3) (DAP-like kinase) (Dlk) (ZIP-kinase) Length = 448 Score = 91.3 bits (225), Expect = 2e-18 Identities = 49/135 (36%), Positives = 76/135 (56%), Gaps = 3/135 (2%) Frame = +3 Query: 174 EDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSK---ADKEDIRREIQ 344 EDV Y +G+ELG GQF + C + TG +YA K I KR+L S +E+I RE+ Sbjct: 7 EDVEDHYEMGEELGSGQFAIVRKCQQKGTGMEYAAKFIKKRRLPSSRRGVSREEIEREVS 66 Query: 345 IMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVN 524 I++ + PNI+ +E+K V +++EL +GGELFD + K +E A + +++ Sbjct: 67 ILREIR-HPNIITLHDVFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILD 125 Query: 525 VVNVCHFMGVMHRDL 569 V+ H + H DL Sbjct: 126 GVHYLHSKRIAHFDL 140
>CDPK3_PLAYO (Q7RAV5) Calcium-dependent protein kinase 3 (EC 2.7.11.1)| Length = 538 Score = 91.3 bits (225), Expect = 2e-18 Identities = 48/132 (36%), Positives = 80/132 (60%), Gaps = 1/132 (0%) Frame = +3 Query: 177 DVRSVYSLGKE-LGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQ 353 ++ Y+L +E LG+G +G Y T+ Q A K +SK+KL + R+EI IM+ Sbjct: 106 NLEDFYNLSEEPLGKGTYGCVYKATDKLLKIQRAVKVVSKKKL---KNIPRFRQEIDIMK 162 Query: 354 HLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVN 533 +L PN+++ +ED+ ++++M+LC GGELFD+II KG + E A+ I + + +V+N Sbjct: 163 NLD-HPNVIKLLETFEDEEQIYLIMDLCTGGELFDKIIKKGSFVEMYASFIMKQIFSVLN 221 Query: 534 VCHFMGVMHRDL 569 H + HRD+ Sbjct: 222 YLHIRNICHRDI 233
>KCC4_MOUSE (P08414) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) Length = 469 Score = 90.9 bits (224), Expect = 2e-18 Identities = 49/136 (36%), Positives = 74/136 (54%) Frame = +3 Query: 162 GKQYEDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREI 341 G + + + + ELGRG + Y C + T + YA K + K DK+ +R EI Sbjct: 32 GSNRDPLGDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKKT-----VDKKIVRTEI 86 Query: 342 QIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVV 521 ++ LS PNI++ +E + +V+EL GGELFDRI+ KG+YSER A + ++ Sbjct: 87 GVLLRLS-HPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDARDAVKQIL 145 Query: 522 NVVNVCHFMGVMHRDL 569 V H G++HRDL Sbjct: 146 EAVAYLHENGIVHRDL 161
>NUAK1_MOUSE (Q641K5) NUAK family, SNF1-like kinase 1 (EC 2.7.11.1)| Length = 658 Score = 90.5 bits (223), Expect = 3e-18 Identities = 50/126 (39%), Positives = 72/126 (57%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y L + LG+G +G TE +GR A KSI K K+ + D IRREI+IM L+ P Sbjct: 56 YELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDELDMVHIRREIEIMSSLN-HP 114 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 +I+ +E+K + ++ME + GEL+D I + SER R +V+ V+ CH G Sbjct: 115 HIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNG 174 Query: 552 VMHRDL 569 V+HRDL Sbjct: 175 VVHRDL 180
>KCC2A_MOUSE (P11798) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 90.5 bits (223), Expect = 3e-18 Identities = 48/126 (38%), Positives = 76/126 (60%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y L +ELG+G F V C ++ G++Y K I+ +KL S D + + RE +I + L P Sbjct: 13 YQLFEELGKGAFSVVRRCVKVLAGQEYPAKIINTKKL-SARDHQKLEREARICRLLK-HP 70 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NIV + ++G +++ +L GGELF+ I+A+ +YSE A+ + ++ V CH MG Sbjct: 71 NIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMG 130 Query: 552 VMHRDL 569 V+HRDL Sbjct: 131 VVHRDL 136
>NUAK1_HUMAN (O60285) NUAK family, SNF1-like kinase 1 (EC 2.7.11.1)| (AMPK-related protein kinase 5) Length = 661 Score = 90.5 bits (223), Expect = 3e-18 Identities = 50/126 (39%), Positives = 72/126 (57%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y L + LG+G +G TE +GR A KSI K K+ + D IRREI+IM L+ P Sbjct: 55 YELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLN-HP 113 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 +I+ +E+K + ++ME + GEL+D I + SER R +V+ V+ CH G Sbjct: 114 HIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNG 173 Query: 552 VMHRDL 569 V+HRDL Sbjct: 174 VVHRDL 179
>DAPK2_MOUSE (Q8VDF3) Death-associated protein kinase 2 (EC 2.7.11.1) (DAP| kinase 2) (DAP-kinase-related protein 1) (DRP-1) Length = 370 Score = 90.1 bits (222), Expect = 4e-18 Identities = 51/137 (37%), Positives = 78/137 (56%), Gaps = 5/137 (3%) Frame = +3 Query: 174 EDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADK-----EDIRRE 338 + V Y +G+ELG GQF + C E STG +YA K I KR+ S+A + E+I RE Sbjct: 17 QKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQ--SRASRRGVCREEIERE 74 Query: 339 IQIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGV 518 + I++ + PNI+ YE++ V +++EL +GGELFD + K SE A + + + Sbjct: 75 VSILRQVL-HPNIITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQI 133 Query: 519 VNVVNVCHFMGVMHRDL 569 ++ VN H + H DL Sbjct: 134 LDGVNYLHTKKIAHFDL 150
>KCC1B_HUMAN (Q6P2M8) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase) Length = 343 Score = 89.4 bits (220), Expect = 7e-18 Identities = 50/138 (36%), Positives = 77/138 (55%) Frame = +3 Query: 156 ILGKQYEDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRR 335 +L K ED+ SVY + + LG G F L E + A K I K+ L K + + Sbjct: 3 LLKKHTEDISSVYEIRERLGSGAFSEVVLAQERGSAHLVALKCIPKKALRGK--EALVEN 60 Query: 336 EIQIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRG 515 EI +++ +S PNIV +E +++ MEL GGELFDRI+ +G Y+E+ A+ + Sbjct: 61 EIAVLRRIS-HPNIVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQ 119 Query: 516 VVNVVNVCHFMGVMHRDL 569 V+ V+ H +G++HRDL Sbjct: 120 VLGAVSYLHSLGIVHRDL 137
>KCC2B_RAT (P08413) Calcium/calmodulin-dependent protein kinase type II beta| chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II beta subunit) (CaMK-II beta subunit) Length = 542 Score = 89.0 bits (219), Expect = 9e-18 Identities = 48/126 (38%), Positives = 76/126 (60%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y L +++G+G F V C ++ TG +YA K I+ +KL S D + + RE +I + L Sbjct: 14 YQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKL-SARDHQKLEREARICRLLK-HS 71 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NIV + ++G ++V +L GGELF+ I+A+ +YSE A+ + ++ V CH MG Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMG 131 Query: 552 VMHRDL 569 V+HRDL Sbjct: 132 VVHRDL 137
>KCC2B_MOUSE (P28652) Calcium/calmodulin-dependent protein kinase type II beta| chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II beta subunit) (CaMK-II beta subunit) Length = 542 Score = 89.0 bits (219), Expect = 9e-18 Identities = 48/126 (38%), Positives = 76/126 (60%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y L +++G+G F V C ++ TG +YA K I+ +KL S D + + RE +I + L Sbjct: 14 YQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKL-SARDHQKLEREARICRLLK-HS 71 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NIV + ++G ++V +L GGELF+ I+A+ +YSE A+ + ++ V CH MG Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMG 131 Query: 552 VMHRDL 569 V+HRDL Sbjct: 132 VVHRDL 137
>KCC2B_HUMAN (Q13554) Calcium/calmodulin-dependent protein kinase type II beta| chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II beta subunit) (CaMK-II beta subunit) Length = 664 Score = 89.0 bits (219), Expect = 9e-18 Identities = 48/126 (38%), Positives = 76/126 (60%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y L +++G+G F V C ++ TG +YA K I+ +KL S D + + RE +I + L Sbjct: 14 YQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKL-SARDHQKLEREARICRLLK-HS 71 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NIV + ++G ++V +L GGELF+ I+A+ +YSE A+ + ++ V CH MG Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMG 131 Query: 552 VMHRDL 569 V+HRDL Sbjct: 132 VVHRDL 137
>KCC2A_DROME (Q00168) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) Length = 530 Score = 88.2 bits (217), Expect = 1e-17 Identities = 47/126 (37%), Positives = 77/126 (61%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y + +ELG+G F + C + STG ++A K I+ +KL ++ D + + RE +I + L P Sbjct: 14 YDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTAR-DFQKLEREARICRKLH-HP 71 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NIV + +++ ++V +L GGELF+ I+A+ YSE A+ + ++ VN CH G Sbjct: 72 NIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNG 131 Query: 552 VMHRDL 569 V+HRDL Sbjct: 132 VVHRDL 137
>KS6A5_CHICK (Q5F3L1) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1)| Length = 789 Score = 87.0 bits (214), Expect = 3e-17 Identities = 49/122 (40%), Positives = 69/122 (56%) Frame = +3 Query: 204 KELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQPNIVE 383 K LG G F + C T ++YA K ISKR + + +REI ++ G PN+V+ Sbjct: 420 KPLGEGSFSICRKCLHKKTSQEYAVKIISKRM------EANTQREITALKLCEGHPNVVK 473 Query: 384 FCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMGVMHR 563 Y D+ +VMEL GGEL +RI K H+SE A+ I R +V+ V+ H +GV+HR Sbjct: 474 LHEVYHDQLHTFLVMELLKGGELLERIQKKQHFSETEASHIMRRLVSAVSHMHDVGVVHR 533 Query: 564 DL 569 DL Sbjct: 534 DL 535 Score = 66.6 bits (161), Expect = 5e-11 Identities = 37/130 (28%), Positives = 67/130 (51%), Gaps = 4/130 (3%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEIS---TGRQYACKSISKRKLVSKADK-EDIRREIQIMQHL 359 + L K LG G +G +L ++S G+ YA K + K +V KA E R E Q+++H+ Sbjct: 39 FELLKVLGTGAYGKVFLVRKVSGHDAGKLYAMKVLKKATIVQKAKTTEHTRTERQVLEHI 98 Query: 360 SGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVC 539 P +V A++ +H++++ GGELF + + +SE +V + Sbjct: 99 RQSPFLVTLHYAFQTDTKLHLILDYINGGELFTHLSQRERFSENEVQIYIGEIVLALEHL 158 Query: 540 HFMGVMHRDL 569 H +G+++RD+ Sbjct: 159 HKLGIIYRDI 168
>KIN11_ARATH (P92958) SNF1-related protein kinase catalytic alpha subunit KIN11| (EC 2.7.11.1) (AKIN11) (AKIN alpha1) Length = 512 Score = 86.7 bits (213), Expect = 4e-17 Identities = 48/132 (36%), Positives = 72/132 (54%) Frame = +3 Query: 174 EDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQ 353 E + Y LGK LG G FG + + TG + A K +++RK+ + +E +RREI+I++ Sbjct: 14 ESILPNYKLGKTLGIGSFGKVKIAEHVVTGHKVAIKILNRRKIKNMEMEEKVRREIKILR 73 Query: 354 HLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVN 533 L P+I+ E ++VVME GELFD I+ KG E A + +++ V Sbjct: 74 -LFMHPHIIRQYEVIETTSDIYVVMEYVKSGELFDYIVEKGRLQEDEARNFFQQIISGVE 132 Query: 534 VCHFMGVMHRDL 569 CH V+HRDL Sbjct: 133 YCHRNMVVHRDL 144
>DAPK2_HUMAN (Q9UIK4) Death-associated protein kinase 2 (EC 2.7.11.1) (DAP| kinase 2) (DAP-kinase-related protein 1) (DRP-1) Length = 370 Score = 86.7 bits (213), Expect = 4e-17 Identities = 47/135 (34%), Positives = 75/135 (55%), Gaps = 3/135 (2%) Frame = +3 Query: 174 EDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSK---ADKEDIRREIQ 344 + V Y +G+ELG GQF + C E STG +YA K I KR+ + +E+I RE+ Sbjct: 17 QKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREVS 76 Query: 345 IMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVN 524 I++ + N++ YE++ V +++EL +GGELFD + K SE A + + +++ Sbjct: 77 ILRQVLHH-NVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILD 135 Query: 525 VVNVCHFMGVMHRDL 569 VN H + H DL Sbjct: 136 GVNYLHTKKIAHFDL 150
>RAD53_YEAST (P22216) Serine/threonine-protein kinase RAD53 (EC 2.7.11.1)| (Serine-protein kinase 1) Length = 821 Score = 86.3 bits (212), Expect = 6e-17 Identities = 46/120 (38%), Positives = 68/120 (56%) Frame = +3 Query: 210 LGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQPNIVEFC 389 +G+G F E +TG+ +A K ISKRK++ D + RE++++Q L+ P IV Sbjct: 204 VGQGAFATVKKAIERTTGKTFAVKIISKRKVIGNMD--GVTRELEVLQKLN-HPRIVRLK 260 Query: 390 GAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMGVMHRDL 569 G YED S ++VME +GG+L D + A G E A I R ++ + H MG+ HRDL Sbjct: 261 GFYEDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGREISRQILTAIKYIHSMGISHRDL 320
>CDPK4_PLAF7 (Q8IBS5) Calcium-dependent protein kinase 4 (EC 2.7.11.1)| Length = 527 Score = 84.7 bits (208), Expect = 2e-16 Identities = 47/140 (33%), Positives = 79/140 (56%) Frame = +3 Query: 150 DTILGKQYEDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDI 329 + + +QY+ + K LG+G FG L + TG +YA K ISK+ + K DKE + Sbjct: 62 NVVFNEQYKGI-------KILGKGSFGEVILSRDKHTGHEYAIKVISKKHVKRKTDKESL 114 Query: 330 RREIQIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATIC 509 RE+++++ L NI++ +ED ++V ++ GGELFD II++ + E AA I Sbjct: 115 LREVELLKMLD-HINIMKLYEFFEDNNYYYLVSDVYTGGELFDEIISRKRFYEIDAARII 173 Query: 510 RGVVNVVNVCHFMGVMHRDL 569 + +++ + H V+HRDL Sbjct: 174 KQILSGITYMHKNNVVHRDL 193
>KCC1_YEAST (P27466) Calcium/calmodulin-dependent protein kinase I (EC| 2.7.11.17) Length = 446 Score = 84.7 bits (208), Expect = 2e-16 Identities = 48/127 (37%), Positives = 67/127 (52%), Gaps = 1/127 (0%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLV-SKADKEDIRREIQIMQHLSGQ 368 Y GK LG G FGV TG A K + K+ L +K E + E+ I+Q L Sbjct: 37 YVFGKTLGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLH-H 95 Query: 369 PNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFM 548 PNIV F +E K +++ +L GGELFDRI+ KG ++E A I +++ V H Sbjct: 96 PNIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVRILVEILSAVKYMHSQ 155 Query: 549 GVMHRDL 569 ++HRDL Sbjct: 156 NIVHRDL 162
>KCC1_SCHPO (Q9P7I2) Calcium/calmodulin-dependent protein kinase type I (EC| 2.7.11.17) (CaMK-I) Length = 335 Score = 84.3 bits (207), Expect = 2e-16 Identities = 45/127 (35%), Positives = 71/127 (55%), Gaps = 1/127 (0%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQ- 368 Y +G+ LG G + I T + YA K ++K+ + K D ++ EI I++ +S + Sbjct: 31 YRVGRVLGGGTYATVREAVHIETNKMYAAKIMNKKMMEKKQDF--VKNEIAILKRVSYEH 88 Query: 369 PNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFM 548 PNI+ +E +++++ EL GGELFDRI AKG + E AA + R + V H Sbjct: 89 PNILHLVDFFETVNNLYLITELATGGELFDRICAKGSFYEADAAALMRTTTSAVKYLHDN 148 Query: 549 GVMHRDL 569 G++HRDL Sbjct: 149 GIVHRDL 155
>CDPK4_PLAYO (Q7RJG2) Calcium-dependent protein kinase 4 (EC 2.7.11.1)| Length = 527 Score = 84.3 bits (207), Expect = 2e-16 Identities = 47/140 (33%), Positives = 80/140 (57%) Frame = +3 Query: 150 DTILGKQYEDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDI 329 + + +QY+ + K LG+G FG L + TG +YA K ISK+ + K DK+ + Sbjct: 62 NVVFNEQYKGI-------KILGKGSFGEVILSKDKHTGHEYAIKVISKKHVKRKTDKQSL 114 Query: 330 RREIQIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATIC 509 RE+++++ L NI++ +ED ++V ++ +GGELFD II++ + E AA I Sbjct: 115 LREVELLKMLD-HINIMKLYEFFEDNNYYYLVSDVYSGGELFDEIISRKRFYEVDAARII 173 Query: 510 RGVVNVVNVCHFMGVMHRDL 569 + V++ + H V+HRDL Sbjct: 174 KQVLSGITYMHKNNVVHRDL 193
>CDPK4_PLABA (P62345) Calcium-dependent protein kinase 4 (EC 2.7.11.1) (PbCDPK4)| Length = 527 Score = 84.3 bits (207), Expect = 2e-16 Identities = 47/140 (33%), Positives = 80/140 (57%) Frame = +3 Query: 150 DTILGKQYEDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDI 329 + + +QY+ + K LG+G FG L + TG +YA K ISK+ + K DK+ + Sbjct: 62 NVVFNEQYKGI-------KILGKGSFGEVILSKDKHTGHEYAIKVISKKHVKRKTDKQSL 114 Query: 330 RREIQIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATIC 509 RE+++++ L NI++ +ED ++V ++ +GGELFD II++ + E AA I Sbjct: 115 LREVELLKMLD-HINIMKLYEFFEDNNYYYLVSDVYSGGELFDEIISRKRFYEVDAARII 173 Query: 510 RGVVNVVNVCHFMGVMHRDL 569 + V++ + H V+HRDL Sbjct: 174 KQVLSGITYMHKNNVVHRDL 193
>KCC2_YEAST (P22517) Calcium/calmodulin-dependent protein kinase II (EC| 2.7.11.17) Length = 447 Score = 84.0 bits (206), Expect = 3e-16 Identities = 48/130 (36%), Positives = 71/130 (54%), Gaps = 1/130 (0%) Frame = +3 Query: 183 RSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLV-SKADKEDIRREIQIMQHL 359 R+ Y G+ LG G FGV ++ST A K + K+ L + + + E+ I+Q L Sbjct: 44 RTNYIFGRTLGAGSFGVVRQARKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKL 103 Query: 360 SGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVC 539 S PNIV F +E K ++V +L GGELFDRI+++G ++E A I ++ V Sbjct: 104 S-HPNIVSFKDWFESKDKFYIVTQLATGGELFDRILSRGKFTEVDAVEIIVQILGAVEYM 162 Query: 540 HFMGVMHRDL 569 H V+HRDL Sbjct: 163 HSKNVVHRDL 172
>KS6AB_XENLA (P10666) Ribosomal protein S6 kinase 2 beta (EC 2.7.11.1)| (Ribosomal protein S6 kinase II beta) (S6KII-beta) (P90-RSK) Length = 629 Score = 84.0 bits (206), Expect = 3e-16 Identities = 46/127 (36%), Positives = 66/127 (51%) Frame = +3 Query: 189 VYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQ 368 VY++ + +G G + V C T +YA K I K K D EI+I++ Sbjct: 415 VYTVRETIGVGSYSVCKRCVHKGTNMEYAVKVIDK-------SKRDPSEEIEILRRYGQH 467 Query: 369 PNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFM 548 PNI+ YE+ S+++V EL GGEL DRI+ + +SER A ++ V V H Sbjct: 468 PNIITLKDVYEECNSIYLVTELMRGGELLDRILRQKFFSEREACSVLFTVCKTVEYLHSQ 527 Query: 549 GVMHRDL 569 GV+HRDL Sbjct: 528 GVVHRDL 534 Score = 48.5 bits (114), Expect = 1e-05 Identities = 34/133 (25%), Positives = 67/133 (50%), Gaps = 4/133 (3%) Frame = +3 Query: 183 RSVYSLGKELGRGQFGVTYLCTEIS---TGRQYACKSISKRKL-VSKADKEDIRREIQIM 350 +S + L K LG+G FG +L +I+ + YA K + K L V + + R+I Sbjct: 59 QSHFVLLKVLGQGSFGKVFLVRKITPPDANQLYAMKVLKKATLKVRDRVRTKMERDILAD 118 Query: 351 QHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVV 530 H P +V A++ +G ++++++ GG+LF R+ + ++E + + Sbjct: 119 VH---HPFVVRLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGL 175 Query: 531 NVCHFMGVMHRDL 569 + H +G+++RDL Sbjct: 176 DHLHSLGIIYRDL 188
>CIPK1_ARATH (Q8RWC9) CBL-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (SOS2-like protein kinase PKS13) (SNF1-related kinase 3.16) Length = 444 Score = 84.0 bits (206), Expect = 3e-16 Identities = 44/126 (34%), Positives = 68/126 (53%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y LG+ LG G FG + +G +A K I K ++ I+REI+ ++ L P Sbjct: 20 YELGRTLGEGNFGKVKFAKDTVSGHSFAVKIIDKSRIADLNFSLQIKREIRTLKMLK-HP 78 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 +IV K +++VMEL GGELFDRI++ G +E + + +++ ++ CH G Sbjct: 79 HIVRLHEVLASKTKINMVMELVTGGELFDRIVSNGKLTETDGRKMFQQLIDGISYCHSKG 138 Query: 552 VMHRDL 569 V HRDL Sbjct: 139 VFHRDL 144
>MARK1_RAT (O08678) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) Length = 793 Score = 83.6 bits (205), Expect = 4e-16 Identities = 46/126 (36%), Positives = 73/126 (57%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y L K +G+G F L + TGR+ A K I K +L + + + RE++IM+ L+ P Sbjct: 60 YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQL-NPTSLQKLFREVRIMKILN-HP 117 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NIV+ E + ++++VME +GGE+FD ++A G E+ A R +V+ V CH Sbjct: 118 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKC 177 Query: 552 VMHRDL 569 ++HRDL Sbjct: 178 IVHRDL 183
>CDPK2_PLAFK (O15865) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (PfCDPK2)| Length = 512 Score = 83.6 bits (205), Expect = 4e-16 Identities = 47/129 (36%), Positives = 76/129 (58%), Gaps = 3/129 (2%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRR---EIQIMQHLS 362 Y + ++LG+G +G Y + T + YA K K +L ++I R EI+IM+ L Sbjct: 71 YIIDEKLGQGTYGCVYKGIDKVTNQLYAIKEEKKDRL------KNINRFFQEIEIMKKLD 124 Query: 363 GQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCH 542 PNIV+ YE+ ++++MELC+G ELFD II G ++E+ AATI + + + + H Sbjct: 125 -HPNIVKLYETYENDNYIYLIMELCSGRELFDSIIENGSFTEKNAATIMKQIFSAIFYLH 183 Query: 543 FMGVMHRDL 569 + ++HRDL Sbjct: 184 SLNIVHRDL 192
>CDPK2_PLAF7 (Q8ICR0) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (PfCDPK2)| Length = 508 Score = 83.6 bits (205), Expect = 4e-16 Identities = 47/129 (36%), Positives = 76/129 (58%), Gaps = 3/129 (2%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRR---EIQIMQHLS 362 Y + ++LG+G +G Y + T + YA K K +L ++I R EI+IM+ L Sbjct: 71 YIIDEKLGQGTYGCVYKGIDKVTNQLYAIKEEKKDRL------KNINRFFQEIEIMKKLD 124 Query: 363 GQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCH 542 PNIV+ YE+ ++++MELC+G ELFD II G ++E+ AATI + + + + H Sbjct: 125 -HPNIVKLYETYENDNYIYLIMELCSGRELFDSIIENGSFTEKNAATIMKQIFSAIFYLH 183 Query: 543 FMGVMHRDL 569 + ++HRDL Sbjct: 184 SLNIVHRDL 192
>MARK1_MOUSE (Q8VHJ5) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) (ELKL motif serine/threonine-protein kinase 3) Length = 795 Score = 83.6 bits (205), Expect = 4e-16 Identities = 46/126 (36%), Positives = 73/126 (57%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y L K +G+G F L + TGR+ A K I K +L + + + RE++IM+ L+ P Sbjct: 60 YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQL-NPTSLQKLFREVRIMKILN-HP 117 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NIV+ E + ++++VME +GGE+FD ++A G E+ A R +V+ V CH Sbjct: 118 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKC 177 Query: 552 VMHRDL 569 ++HRDL Sbjct: 178 IVHRDL 183
>MARK1_HUMAN (Q9P0L2) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) Length = 795 Score = 83.6 bits (205), Expect = 4e-16 Identities = 46/126 (36%), Positives = 73/126 (57%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y L K +G+G F L + TGR+ A K I K +L + + + RE++IM+ L+ P Sbjct: 60 YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQL-NPTSLQKLFREVRIMKILN-HP 117 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NIV+ E + ++++VME +GGE+FD ++A G E+ A R +V+ V CH Sbjct: 118 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKY 177 Query: 552 VMHRDL 569 ++HRDL Sbjct: 178 IVHRDL 183
>KS6AA_XENLA (P10665) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 733 Score = 83.2 bits (204), Expect = 5e-16 Identities = 46/127 (36%), Positives = 67/127 (52%) Frame = +3 Query: 189 VYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQ 368 VY++ + +G G + V C T +YA K I K K D EI+I++ Sbjct: 415 VYTVRETIGVGSYSVCKRCVHKGTNMEYAVKVIDKTK-------RDPSEEIEILRRYGQH 467 Query: 369 PNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFM 548 PNI+ Y++ S++VV EL GGEL DRI+ + +SER A+++ V V H Sbjct: 468 PNIIALKDVYKEGNSIYVVTELMRGGELLDRILRQKFFSEREASSVLFTVCKTVENLHSQ 527 Query: 549 GVMHRDL 569 GV+HRDL Sbjct: 528 GVVHRDL 534 Score = 48.5 bits (114), Expect = 1e-05 Identities = 34/133 (25%), Positives = 67/133 (50%), Gaps = 4/133 (3%) Frame = +3 Query: 183 RSVYSLGKELGRGQFGVTYLCTEIS---TGRQYACKSISKRKL-VSKADKEDIRREIQIM 350 +S + L K LG+G FG +L +I+ + YA K + K L V + + R+I Sbjct: 59 QSDFVLLKVLGQGSFGKVFLVRKITPPDANQLYAMKVLKKATLKVRDRVRTKMERDILAD 118 Query: 351 QHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVV 530 H P +V A++ +G ++++++ GG+LF R+ + ++E + + Sbjct: 119 VH---HPFVVRLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGL 175 Query: 531 NVCHFMGVMHRDL 569 + H +G+++RDL Sbjct: 176 DHLHSLGIIYRDL 188
>MARK3_MOUSE (Q03141) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| (MPK-10) (ELKL motif kinase 2) Length = 753 Score = 83.2 bits (204), Expect = 5e-16 Identities = 46/126 (36%), Positives = 73/126 (57%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y L K +G+G F L I TGR+ A K I K +L + + + RE++IM+ L+ P Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQL-NPTSLQKLFREVRIMKILN-HP 113 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NIV+ E + +++++ME +GGE+FD ++A G E+ A R +V+ V CH Sbjct: 114 NIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKR 173 Query: 552 VMHRDL 569 ++HRDL Sbjct: 174 IVHRDL 179
>MARK3_RAT (Q8VHF0) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| Length = 797 Score = 83.2 bits (204), Expect = 5e-16 Identities = 46/126 (36%), Positives = 73/126 (57%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y L K +G+G F L I TGR+ A K I K +L + + + RE++IM+ L+ P Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQL-NPTSLQKLFREVRIMKILN-HP 113 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NIV+ E + +++++ME +GGE+FD ++A G E+ A R +V+ V CH Sbjct: 114 NIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKR 173 Query: 552 VMHRDL 569 ++HRDL Sbjct: 174 IVHRDL 179
>MARK2_RAT (O08679) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1) Length = 722 Score = 82.8 bits (203), Expect = 6e-16 Identities = 47/126 (37%), Positives = 74/126 (58%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y L K +G+G F L I TG++ A K I K +L S + + + RE++IM+ L+ P Sbjct: 53 YRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSS-LQKLFREVRIMKVLN-HP 110 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NIV+ E + ++++VME +GGE+FD ++A G E+ A R +V+ V CH Sbjct: 111 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKF 170 Query: 552 VMHRDL 569 ++HRDL Sbjct: 171 IVHRDL 176
>KS6A5_PONPY (Q5R4K3) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1)| Length = 802 Score = 82.8 bits (203), Expect = 6e-16 Identities = 47/122 (38%), Positives = 69/122 (56%) Frame = +3 Query: 204 KELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQPNIVE 383 K LG G F + C + + +A K ISKR + + ++EI ++ G PNIV+ Sbjct: 430 KPLGEGSFSICRKCVHKKSNQAFAVKIISKRM------EANTQKEITALKLCEGHPNIVK 483 Query: 384 FCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMGVMHR 563 + D+ +VMEL GGELF+RI K H+SE A+ I R +V+ V+ H +GV+HR Sbjct: 484 LHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGVVHR 543 Query: 564 DL 569 DL Sbjct: 544 DL 545 Score = 67.4 bits (163), Expect = 3e-11 Identities = 38/130 (29%), Positives = 68/130 (52%), Gaps = 4/130 (3%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEIS---TGRQYACKSISKRKLVSKADK-EDIRREIQIMQHL 359 + L K LG G +G +L +IS TG+ YA K + K +V KA E R E Q+++H Sbjct: 49 FELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVLEHT 108 Query: 360 SGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVC 539 P +V A++ + +H++++ GGELF + + ++E +V + Sbjct: 109 RQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHL 168 Query: 540 HFMGVMHRDL 569 H +G+++RD+ Sbjct: 169 HKLGIIYRDI 178
>KS6A5_HUMAN (O75582) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RSKL) Length = 802 Score = 82.8 bits (203), Expect = 6e-16 Identities = 47/122 (38%), Positives = 69/122 (56%) Frame = +3 Query: 204 KELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQPNIVE 383 K LG G F + C + + +A K ISKR + + ++EI ++ G PNIV+ Sbjct: 430 KPLGEGSFSICRKCVHKKSNQAFAVKIISKRM------EANTQKEITALKLCEGHPNIVK 483 Query: 384 FCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMGVMHR 563 + D+ +VMEL GGELF+RI K H+SE A+ I R +V+ V+ H +GV+HR Sbjct: 484 LHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGVVHR 543 Query: 564 DL 569 DL Sbjct: 544 DL 545 Score = 68.6 bits (166), Expect = 1e-11 Identities = 38/130 (29%), Positives = 69/130 (53%), Gaps = 4/130 (3%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEIS---TGRQYACKSISKRKLVSKADK-EDIRREIQIMQHL 359 + L K LG G +G +L +IS TG+ YA K + K +V KA E R E Q+++H+ Sbjct: 49 FELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVLEHI 108 Query: 360 SGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVC 539 P +V A++ + +H++++ GGELF + + ++E +V + Sbjct: 109 RQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHL 168 Query: 540 HFMGVMHRDL 569 H +G+++RD+ Sbjct: 169 HKLGIIYRDI 178
>MARK2_HUMAN (Q7KZI7) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog) Length = 788 Score = 82.8 bits (203), Expect = 6e-16 Identities = 47/126 (37%), Positives = 74/126 (58%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y L K +G+G F L I TG++ A K I K +L S + + + RE++IM+ L+ P Sbjct: 53 YRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSS-LQKLFREVRIMKVLN-HP 110 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NIV+ E + ++++VME +GGE+FD ++A G E+ A R +V+ V CH Sbjct: 111 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKF 170 Query: 552 VMHRDL 569 ++HRDL Sbjct: 171 IVHRDL 176
>KS6A2_HUMAN (Q15349) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (MAP kinase-activated protein kinase 1c) (MAPKAPK1C) Length = 733 Score = 82.8 bits (203), Expect = 6e-16 Identities = 44/126 (34%), Positives = 67/126 (53%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y + +++G G + V C +T +YA K I K K D EI+I+ P Sbjct: 415 YEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDK-------SKRDPSEEIEILLRYGQHP 467 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NI+ Y+D V++VMEL GGEL DRI+ + ++SER A+ + + ++ H G Sbjct: 468 NIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQG 527 Query: 552 VMHRDL 569 V+HRDL Sbjct: 528 VVHRDL 533 Score = 52.4 bits (124), Expect = 9e-07 Identities = 33/131 (25%), Positives = 69/131 (52%), Gaps = 3/131 (2%) Frame = +3 Query: 186 SVYSLGKELGRGQFGVTYLCTEIS---TGRQYACKSISKRKLVSKADKEDIRREIQIMQH 356 S + L K LG+G +G +L ++ G+ YA K + K L + D+ + E I+ Sbjct: 57 SQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVR-DRVRSKMERDILAE 115 Query: 357 LSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNV 536 ++ P IV+ A++ +G ++++++ GG+LF R+ + ++E + ++ Sbjct: 116 VN-HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDH 174 Query: 537 CHFMGVMHRDL 569 H +G+++RDL Sbjct: 175 LHSLGIIYRDL 185
>KIN10_ARATH (Q38997) SNF1-related protein kinase catalytic alpha subunit KIN10| (EC 2.7.11.1) (AKIN10) (AKIN alpha2) Length = 535 Score = 82.4 bits (202), Expect = 8e-16 Identities = 46/132 (34%), Positives = 71/132 (53%) Frame = +3 Query: 174 EDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQ 353 E + Y LG+ LG G FG + TG + A K +++RK+ + +E +RREI+I++ Sbjct: 36 ESILPNYKLGRTLGIGSFGRVKIAEHALTGHKVAIKILNRRKIKNMEMEEKVRREIKILR 95 Query: 354 HLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVN 533 L P+I+ E +++VME GELFD I+ KG E A + +++ V Sbjct: 96 -LFMHPHIIRLYEVIETPTDIYLVMEYVNSGELFDYIVEKGRLQEDEARNFFQQIISGVE 154 Query: 534 VCHFMGVMHRDL 569 CH V+HRDL Sbjct: 155 YCHRNMVVHRDL 166
>CPK11_ARATH (O22932) CBL-interacting serine/threonine-protein kinase 11 (EC| 2.7.11.1) (SOS2-like protein kinase PKS5) (SOS-interacting protein 4) (SNF1-related kinase 3.22) Length = 435 Score = 82.4 bits (202), Expect = 8e-16 Identities = 49/127 (38%), Positives = 69/127 (54%), Gaps = 1/127 (0%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSK-ADKEDIRREIQIMQHLSGQ 368 Y LGK LG G F + + TG+ A K ++K+KL++ A +I+REI IM+ LS Sbjct: 21 YELGKLLGCGAFAKVFHARDRRTGQSVAVKILNKKKLLTNPALANNIKREISIMRRLS-H 79 Query: 369 PNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFM 548 PNIV+ K + ME GGELF++I G SE + + +++ V CH Sbjct: 80 PNIVKLHEVMATKSKIFFAMEFVKGGELFNKISKHGRLSEDLSRRYFQQLISAVGYCHAR 139 Query: 549 GVMHRDL 569 GV HRDL Sbjct: 140 GVYHRDL 146
>KCC2G_RAT (P11730) Calcium/calmodulin-dependent protein kinase type II gamma| chain (EC 2.7.11.17) (CaM-kinase II gamma chain) (CaM kinase II gamma subunit) (CaMK-II gamma subunit) Length = 527 Score = 81.3 bits (199), Expect = 2e-15 Identities = 46/126 (36%), Positives = 74/126 (58%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y L +ELG+G F V C + ++ ++YA K I+ +KL S D + + RE +I + L P Sbjct: 14 YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKL-SARDHQKLEREARICRLLK-HP 71 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NIV + ++G ++V +L GGELF+ I+A+ +YSE A+ ++ VN H Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHD 131 Query: 552 VMHRDL 569 ++HRDL Sbjct: 132 IVHRDL 137
>KCC2G_MOUSE (Q923T9) Calcium/calmodulin-dependent protein kinase type II gamma| chain (EC 2.7.11.17) (CaM-kinase II gamma chain) (CaM kinase II gamma subunit) (CaMK-II gamma subunit) Length = 529 Score = 81.3 bits (199), Expect = 2e-15 Identities = 46/126 (36%), Positives = 74/126 (58%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y L +ELG+G F V C + ++ ++YA K I+ +KL S D + + RE +I + L P Sbjct: 14 YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKL-SARDHQKLEREARICRLLK-HP 71 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NIV + ++G ++V +L GGELF+ I+A+ +YSE A+ ++ VN H Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHD 131 Query: 552 VMHRDL 569 ++HRDL Sbjct: 132 IVHRDL 137
>KCC2G_HUMAN (Q13555) Calcium/calmodulin-dependent protein kinase type II gamma| chain (EC 2.7.11.17) (CaM-kinase II gamma chain) (CaM kinase II gamma subunit) (CaMK-II gamma subunit) Length = 558 Score = 81.3 bits (199), Expect = 2e-15 Identities = 46/126 (36%), Positives = 74/126 (58%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y L +ELG+G F V C + ++ ++YA K I+ +KL S D + + RE +I + L P Sbjct: 14 YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKL-SARDHQKLEREARICRLLK-HP 71 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NIV + ++G ++V +L GGELF+ I+A+ +YSE A+ ++ VN H Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHD 131 Query: 552 VMHRDL 569 ++HRDL Sbjct: 132 IVHRDL 137
>KS6A2_MOUSE (Q9WUT3) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (Protein-tyrosine kinase Mpk-9) (MAP kinase-activated protein kinase 1c) (M Length = 733 Score = 81.3 bits (199), Expect = 2e-15 Identities = 44/126 (34%), Positives = 66/126 (52%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y + +++G G + V C +T +YA K I K K D EI+I+ P Sbjct: 415 YEIKEDIGVGSYSVCKRCVHKATDAEYAVKIIDK-------SKRDPSEEIEILLRYGQHP 467 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NI+ Y+D V++VMEL GGEL DRI+ + +SER A+ + + ++ H G Sbjct: 468 NIITLKDVYDDGKYVYLVMELMRGGELLDRILRQRCFSEREASDVLYTIARTMDYLHSQG 527 Query: 552 VMHRDL 569 V+HRDL Sbjct: 528 VVHRDL 533 Score = 52.4 bits (124), Expect = 9e-07 Identities = 33/131 (25%), Positives = 70/131 (53%), Gaps = 3/131 (2%) Frame = +3 Query: 186 SVYSLGKELGRGQFGVTYLCTEIS---TGRQYACKSISKRKLVSKADKEDIRREIQIMQH 356 S + L K LG+G +G +L +++ G+ YA K + K L + D+ + E I+ Sbjct: 57 SQFELLKVLGQGSYGKVFLVRKVTGSDAGQLYAMKVLKKATLKVR-DRVRSKMERDILAE 115 Query: 357 LSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNV 536 ++ P IV+ A++ +G ++++++ GG+LF R+ + ++E + ++ Sbjct: 116 VN-HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDH 174 Query: 537 CHFMGVMHRDL 569 H +G+++RDL Sbjct: 175 LHGLGIIYRDL 185
>MARK4_MOUSE (Q8CIP4) MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1)| Length = 752 Score = 80.9 bits (198), Expect = 2e-15 Identities = 44/126 (34%), Positives = 74/126 (58%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y L + +G+G F L I TGR+ A K I K +L + + + + RE++IM+ L+ P Sbjct: 59 YRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQL-NPSSLQKLFREVRIMKGLN-HP 116 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NIV+ E + ++++VME + GE+FD +++ G E+ A R +V+ V+ CH Sbjct: 117 NIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKN 176 Query: 552 VMHRDL 569 ++HRDL Sbjct: 177 IVHRDL 182
>MARK4_HUMAN (Q96L34) MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase-like 1) Length = 752 Score = 80.9 bits (198), Expect = 2e-15 Identities = 44/126 (34%), Positives = 74/126 (58%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y L + +G+G F L I TGR+ A K I K +L + + + + RE++IM+ L+ P Sbjct: 59 YRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQL-NPSSLQKLFREVRIMKGLN-HP 116 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NIV+ E + ++++VME + GE+FD +++ G E+ A R +V+ V+ CH Sbjct: 117 NIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKN 176 Query: 552 VMHRDL 569 ++HRDL Sbjct: 177 IVHRDL 182
>BRSK1_HUMAN (Q8TDC3) BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1| kinase) (SAD1A) Length = 794 Score = 80.9 bits (198), Expect = 2e-15 Identities = 44/126 (34%), Positives = 75/126 (59%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y L K LG+GQ G+ L TG++ A K +++ KL S++ + REI I++ L P Sbjct: 50 YRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKL-SESVLMKVEREIAILK-LIEHP 107 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 ++++ YE+K +++V+E +GGELFD ++ KG + + A R +V+ ++ CH Sbjct: 108 HVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYS 167 Query: 552 VMHRDL 569 + HRDL Sbjct: 168 ICHRDL 173
>CPK15_ARATH (P92937) CBL-interacting serine/threonine-protein kinase 15 (EC| 2.7.11.1) (Serine/threonine-protein kinase ATPK10) (SOS2-like protein kinase PKS3) (SOS-interacting protein 2) (SNF1-related kinase 3.1) Length = 421 Score = 80.5 bits (197), Expect = 3e-15 Identities = 48/126 (38%), Positives = 65/126 (51%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y +GK LG+G F Y + TG A K I K +++ E I+REI M+ L P Sbjct: 12 YEVGKFLGQGTFAKVYHARHLKTGDSVAIKVIDKERILKVGMTEQIKREISAMR-LLRHP 70 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NIVE K ++ VME GGELF++ ++ G E A + +V V+ CH G Sbjct: 71 NIVELHEVMATKSKIYFVMEHVKGGELFNK-VSTGKLREDVARKYFQQLVRAVDFCHSRG 129 Query: 552 VMHRDL 569 V HRDL Sbjct: 130 VCHRDL 135
>CPK24_ARATH (Q9LDI3) CBL-interacting serine/threonine-protein kinase 24 (EC| 2.7.11.1) (SNF1-related kinase 3.11) (SALT OVERLY SENSITIVE 2 protein) Length = 446 Score = 80.1 bits (196), Expect = 4e-15 Identities = 43/126 (34%), Positives = 63/126 (50%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y +G+ +G G F TG A K ++K ++ + I+REI IM+ + P Sbjct: 11 YEVGRTIGEGTFAKVKFARNTDTGDNVAIKIMAKSTILKNRMVDQIKREISIMK-IVRHP 69 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NIV +++V+E GGELFDRI+ KG E + + +V+ V CH G Sbjct: 70 NIVRLYEVLASPSKIYIVLEFVTGGELFDRIVHKGRLEESESRKYFQQLVDAVAHCHCKG 129 Query: 552 VMHRDL 569 V HRDL Sbjct: 130 VYHRDL 135
>KPK2_PLAFK (Q02595) Probable serine/threonine-protein kinase 2 (EC 2.7.11.1)| Length = 510 Score = 80.1 bits (196), Expect = 4e-15 Identities = 44/138 (31%), Positives = 76/138 (55%) Frame = +3 Query: 156 ILGKQYEDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRR 335 +LG ++VY L K++G+G F Y+ T I G + K + K SK + ++ Sbjct: 99 MLGYPILGFKNVYVLNKKIGKGSFSTAYIGTNILYGNRVVVKEVDK----SKVKESNVYT 154 Query: 336 EIQIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRG 515 EI++++ + + I++ AYE +G V++V+E GGELF+ + G Y+E+ A + Sbjct: 155 EIEVLRKVMHK-YIIKLISAYEQEGFVYLVLEYLKGGELFEYLNNNGPYTEQVAKKAMKR 213 Query: 516 VVNVVNVCHFMGVMHRDL 569 V+ + H GV+HRDL Sbjct: 214 VLIALEALHSNGVVHRDL 231
>MARK2_MOUSE (Q05512) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1) Length = 776 Score = 80.1 bits (196), Expect = 4e-15 Identities = 47/126 (37%), Positives = 73/126 (57%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y L K +G+G F L I TG++ A K I K +L S + + + RE++IM+ L+ P Sbjct: 53 YRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSS-LQKLFREVRIMKVLN-HP 110 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NIV+ E + ++++VME +GGE+FD ++A G E+ A R +V V CH Sbjct: 111 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVLHVQYCHQKF 170 Query: 552 VMHRDL 569 ++HRDL Sbjct: 171 IVHRDL 176
>KCC1G_MOUSE (Q91VB2) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 477 Score = 79.3 bits (194), Expect = 7e-15 Identities = 45/135 (33%), Positives = 75/135 (55%) Frame = +3 Query: 165 KQYEDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQ 344 KQ ++R + + LG G F +L + TG+ +A K I K + E+ EI Sbjct: 14 KQTTNIRKTFIFMEVLGSGAFSEVFLVKQRVTGKLFALKCIKKSPAFRDSSLEN---EIA 70 Query: 345 IMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVN 524 +++ + + NIV YE ++VM+L +GGELFDRI+ +G Y+E+ A+ + + V++ Sbjct: 71 VLKRIKHE-NIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLS 129 Query: 525 VVNVCHFMGVMHRDL 569 V H G++HRDL Sbjct: 130 AVKYLHENGIVHRDL 144
>KCC1G_RAT (Q7TNJ7) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 476 Score = 79.3 bits (194), Expect = 7e-15 Identities = 45/135 (33%), Positives = 75/135 (55%) Frame = +3 Query: 165 KQYEDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQ 344 KQ ++R + + LG G F +L + TG+ +A K I K + E+ EI Sbjct: 14 KQTTNIRKTFIFMEVLGSGAFSEVFLVKQRVTGKLFALKCIKKSPAFRDSSLEN---EIA 70 Query: 345 IMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVN 524 +++ + + NIV YE ++VM+L +GGELFDRI+ +G Y+E+ A+ + + V++ Sbjct: 71 VLKRIKHE-NIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLS 129 Query: 525 VVNVCHFMGVMHRDL 569 V H G++HRDL Sbjct: 130 AVKYLHENGIVHRDL 144
>KS6A6_HUMAN (Q9UK32) Ribosomal protein S6 kinase alpha-6 (EC 2.7.11.1)| (S6K-alpha 6) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4) Length = 745 Score = 79.0 bits (193), Expect = 9e-15 Identities = 44/127 (34%), Positives = 66/127 (51%) Frame = +3 Query: 189 VYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQ 368 VY L +++G G + V C +T ++A K I K K D EI+I+ Sbjct: 425 VYELKEDIGVGSYSVCKRCIHATTNMEFAVKIIDK-------SKRDPSEEIEILMRYGQH 477 Query: 369 PNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFM 548 PNI+ ++D V++V +L GGEL DRI+ + +SER A+ I + V+ H Sbjct: 478 PNIITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHCQ 537 Query: 549 GVMHRDL 569 GV+HRDL Sbjct: 538 GVVHRDL 544 Score = 50.1 bits (118), Expect = 4e-06 Identities = 33/129 (25%), Positives = 67/129 (51%), Gaps = 3/129 (2%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLC---TEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLS 362 + L K LG+G FG +L T G+ YA K + K L + D+ + E I+ ++ Sbjct: 73 FELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVR-DRVRTKMERDILVEVN 131 Query: 363 GQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCH 542 P IV+ A++ +G ++++++ GG++F R+ + ++E + ++ H Sbjct: 132 -HPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLH 190 Query: 543 FMGVMHRDL 569 +G+++RDL Sbjct: 191 QLGIVYRDL 199
>DCAK1_HUMAN (O15075) Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 1) Length = 740 Score = 79.0 bits (193), Expect = 9e-15 Identities = 43/126 (34%), Positives = 69/126 (54%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y +G+ +G G F V C E ST R+YA K I K K K + I+ E+ I++ + P Sbjct: 390 YKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGK--EHMIQNEVSILRRVK-HP 446 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NIV + +++VMEL GG+LFD I + Y+ER A+ + + + + H + Sbjct: 447 NIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLN 506 Query: 552 VMHRDL 569 ++HRD+ Sbjct: 507 IVHRDI 512
>KCC1G_HUMAN (Q96NX5) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 476 Score = 79.0 bits (193), Expect = 9e-15 Identities = 45/135 (33%), Positives = 75/135 (55%) Frame = +3 Query: 165 KQYEDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQ 344 KQ ++R + + LG G F +L + TG+ +A K I K + E+ EI Sbjct: 14 KQTTNIRKTFIFMEVLGSGAFSEVFLVKQRLTGKLFALKCIKKSPAFRDSSLEN---EIA 70 Query: 345 IMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVN 524 +++ + + NIV YE ++VM+L +GGELFDRI+ +G Y+E+ A+ + + V++ Sbjct: 71 VLKKIKHE-NIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLS 129 Query: 525 VVNVCHFMGVMHRDL 569 V H G++HRDL Sbjct: 130 AVKYLHENGIVHRDL 144
>BRSK2_HUMAN (Q8IWQ3) BR serine/threonine-protein kinase 2 (EC 2.7.11.1)| (Serine/threonine-protein kinase 29) (SAD1B) Length = 736 Score = 78.6 bits (192), Expect = 1e-14 Identities = 44/136 (32%), Positives = 77/136 (56%) Frame = +3 Query: 162 GKQYEDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREI 341 G Q+ Y L K LG+GQ G+ L T ++ A K +++ KL S++ + REI Sbjct: 9 GAQHAQYVGPYRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKL-SESVLMKVEREI 67 Query: 342 QIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVV 521 I++ L P++++ YE+K +++V+E +GGELFD ++ KG + + A R ++ Sbjct: 68 AILK-LIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQII 126 Query: 522 NVVNVCHFMGVMHRDL 569 + ++ CH + HRDL Sbjct: 127 SALDFCHSHSICHRDL 142
>CCAMK_MEDTR (Q6RET7) Calcium and calcium/calmodulin-dependent| serine/threonine-protein kinase DMI-3 (EC 2.7.11.17) (Does not make infections protein 3) (CCaMK DMI3) (MtCCaMK) Length = 523 Score = 78.6 bits (192), Expect = 1e-14 Identities = 33/76 (43%), Positives = 52/76 (68%) Frame = +3 Query: 342 QIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVV 521 +I++++S PN+++ YED VH+V+ELC+GGELFDRI+A+ YSE AAT+ + Sbjct: 97 RIVENVSPHPNVIDLYDVYEDTNGVHLVLELCSGGELFDRIVAQDKYSETEAATVVHQIA 156 Query: 522 NVVNVCHFMGVMHRDL 569 + + H ++HRDL Sbjct: 157 SGLEAVHRANIVHRDL 172
>ARK1_SCHPO (O59790) Serine/threonine-protein kinase ark1 (EC 2.7.11.1)| (Aurora-related kinase 1) Length = 355 Score = 78.6 bits (192), Expect = 1e-14 Identities = 42/137 (30%), Positives = 74/137 (54%), Gaps = 1/137 (0%) Frame = +3 Query: 162 GKQYEDVR-SVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRRE 338 G Q+ + ++ +GK LG+G+FG YL E TG A K++ K +LV ++ +RRE Sbjct: 78 GPQWREFHIGMFEIGKPLGKGKFGRVYLAKEKKTGFIVALKTLHKSELVQSKIEKQVRRE 137 Query: 339 IQIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGV 518 I+I +L NI+ G + D+ +++++E GEL+ + +SE A+ + Sbjct: 138 IEIQSNLR-HKNILRLYGHFHDEKRIYLILEFAGRGELYQHLRRAKRFSEEVASKYIFQM 196 Query: 519 VNVVNVCHFMGVMHRDL 569 N ++ H V+HRD+ Sbjct: 197 ANALSYLHKKHVIHRDI 213
>KS6A3_MOUSE (P18654) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B) Length = 740 Score = 78.6 bits (192), Expect = 1e-14 Identities = 43/126 (34%), Positives = 64/126 (50%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y + +++G G + V C +T ++A K I K K D EI+I+ P Sbjct: 422 YEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDK-------SKRDPTEEIEILLRYGQHP 474 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NI+ Y+D V+VV EL GGEL D+I+ + +SER A+ + + V H G Sbjct: 475 NIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQG 534 Query: 552 VMHRDL 569 V+HRDL Sbjct: 535 VVHRDL 540 Score = 54.3 bits (129), Expect = 2e-07 Identities = 33/130 (25%), Positives = 67/130 (51%), Gaps = 2/130 (1%) Frame = +3 Query: 186 SVYSLGKELGRGQFGVTYLCTEIS--TGRQYACKSISKRKLVSKADKEDIRREIQIMQHL 359 S + L K LG+G FG +L +IS RQ + K+ + D+ + E I+ + Sbjct: 66 SQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDILVEV 125 Query: 360 SGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVC 539 + P IV+ A++ +G ++++++ GG+LF R+ + ++E + ++ Sbjct: 126 N-HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHL 184 Query: 540 HFMGVMHRDL 569 H +G+++RDL Sbjct: 185 HSLGIIYRDL 194
>KS6A3_HUMAN (P51812) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protei Length = 740 Score = 78.6 bits (192), Expect = 1e-14 Identities = 43/126 (34%), Positives = 64/126 (50%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y + +++G G + V C +T ++A K I K K D EI+I+ P Sbjct: 422 YEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDK-------SKRDPTEEIEILLRYGQHP 474 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NI+ Y+D V+VV EL GGEL D+I+ + +SER A+ + + V H G Sbjct: 475 NIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQG 534 Query: 552 VMHRDL 569 V+HRDL Sbjct: 535 VVHRDL 540 Score = 54.3 bits (129), Expect = 2e-07 Identities = 33/130 (25%), Positives = 67/130 (51%), Gaps = 2/130 (1%) Frame = +3 Query: 186 SVYSLGKELGRGQFGVTYLCTEIS--TGRQYACKSISKRKLVSKADKEDIRREIQIMQHL 359 S + L K LG+G FG +L +IS RQ + K+ + D+ + E I+ + Sbjct: 66 SQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDILVEV 125 Query: 360 SGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVC 539 + P IV+ A++ +G ++++++ GG+LF R+ + ++E + ++ Sbjct: 126 N-HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHL 184 Query: 540 HFMGVMHRDL 569 H +G+++RDL Sbjct: 185 HSLGIIYRDL 194
>DCAK2_HUMAN (Q8N568) Serine/threonine-protein kinase DCAMKL2 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 2) Length = 766 Score = 78.6 bits (192), Expect = 1e-14 Identities = 42/126 (33%), Positives = 67/126 (53%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y +GK +G G F V C + STG+++A K I K K K + I E+ I++ + P Sbjct: 394 YKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGK--EHLIENEVSILRRVK-HP 450 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NI+ E + +VMEL GG+LFD I + Y+ER + + + N + H + Sbjct: 451 NIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLS 510 Query: 552 VMHRDL 569 ++HRD+ Sbjct: 511 IVHRDI 516
>DCAK1_RAT (O08875) Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 1) (Calcium/calmodulin-dependent protein kinase type I-like CPG16) Length = 433 Score = 78.6 bits (192), Expect = 1e-14 Identities = 43/126 (34%), Positives = 69/126 (54%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y +G+ +G G F V C E ST R+YA K I K K K + I+ E+ I++ + P Sbjct: 83 YKVGRTIGDGNFAVVKECIERSTAREYALKIIKKSKCRGK--EHMIQNEVSILRRVK-HP 139 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NIV + +++VMEL GG+LFD I + Y+ER A+ + + + + H + Sbjct: 140 NIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTSKYTERDASGMLYNLASAIKYLHSLN 199 Query: 552 VMHRDL 569 ++HRD+ Sbjct: 200 IVHRDI 205
>DCAK1_MOUSE (Q9JLM8) Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 1) Length = 756 Score = 78.6 bits (192), Expect = 1e-14 Identities = 43/126 (34%), Positives = 69/126 (54%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y +G+ +G G F V C E ST R+YA K I K K K + I+ E+ I++ + P Sbjct: 406 YKVGRTIGDGNFAVVKECIERSTAREYALKIIKKSKCRGK--EHMIQNEVSILRRVK-HP 462 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NIV + +++VMEL GG+LFD I + Y+ER A+ + + + + H + Sbjct: 463 NIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTSKYTERDASGMLYNLASAIKYLHSLN 522 Query: 552 VMHRDL 569 ++HRD+ Sbjct: 523 IVHRDI 528
>KS6AA_CHICK (P18652) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 752 Score = 78.2 bits (191), Expect = 2e-14 Identities = 43/126 (34%), Positives = 64/126 (50%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y + + +G G + V C +T +YA K I K K D EI+I+ P Sbjct: 435 YVVKEAIGVGSYSVCKRCIHKTTNMEYAVKVIDK-------SKRDPSEEIEILLRYGQHP 487 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NI+ Y+D V++V EL GGEL D+I+ + +SER A+++ + V H G Sbjct: 488 NIITLKDVYDDGKYVYLVTELMRGGELLDKILRQKFFSEREASSVLHTICKTVEYLHSQG 547 Query: 552 VMHRDL 569 V+HRDL Sbjct: 548 VVHRDL 553 Score = 49.7 bits (117), Expect = 6e-06 Identities = 33/131 (25%), Positives = 69/131 (52%), Gaps = 3/131 (2%) Frame = +3 Query: 186 SVYSLGKELGRGQFGVTYLCTEIS---TGRQYACKSISKRKLVSKADKEDIRREIQIMQH 356 S + L K LG+G FG +L +I+ + YA K + K L + D+ + E I+ Sbjct: 78 SQFELLKVLGQGSFGKVFLVRKITPPDSNHLYAMKVLKKATLKVR-DRVRTKIERDILAD 136 Query: 357 LSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNV 536 ++ P +V+ A++ +G ++++++ GG+LF R+ + ++E + ++ Sbjct: 137 VN-HPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDH 195 Query: 537 CHFMGVMHRDL 569 H +G+++RDL Sbjct: 196 LHSLGIIYRDL 206
>MYLK_CHICK (P11799) Myosin light chain kinase, smooth muscle and non-muscle| isozymes (EC 2.7.11.18) (MLCK) [Contains: Telokin] Length = 1906 Score = 78.2 bits (191), Expect = 2e-14 Identities = 48/133 (36%), Positives = 74/133 (55%), Gaps = 1/133 (0%) Frame = +3 Query: 174 EDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQ 353 + V VY++ + LG G+FG + E TG+ +A K K S +KE+IR EI IM Sbjct: 1447 QKVSDVYNIEERLGSGKFGQVFRLVEKKTGKVWAGKFF---KAYSAKEKENIRDEISIMN 1503 Query: 354 HLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKG-HYSERAAATICRGVVNVV 530 L P +V+ A+E+K ++ +V+E+ +GGELF+RII + +ER R + V Sbjct: 1504 CLH-HPKLVQCVDAFEEKANIVMVLEMVSGGELFERIIDEDFELTERECIKYMRQISEGV 1562 Query: 531 NVCHFMGVMHRDL 569 H G++H DL Sbjct: 1563 EYIHKQGIVHLDL 1575
>KPSH1_MOUSE (Q91YA2) Serine/threonine-protein kinase H1 (EC 2.7.11.1) (PSK-H1)| Length = 423 Score = 77.8 bits (190), Expect = 2e-14 Identities = 44/130 (33%), Positives = 72/130 (55%) Frame = +3 Query: 180 VRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHL 359 V + Y + +GRG F +T + YA K I + + +E E+++++ + Sbjct: 93 VTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKY---REGREVCESELRVLRRV 149 Query: 360 SGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVC 539 NI++ +E + V++VMEL GGELFDRIIAKG ++ER A + + V++ V Sbjct: 150 R-HANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYL 208 Query: 540 HFMGVMHRDL 569 H +G+ HRDL Sbjct: 209 HALGITHRDL 218
>KPSH1_HUMAN (P11801) Serine/threonine-protein kinase H1 (EC 2.7.11.1) (PSK-H1)| Length = 423 Score = 77.8 bits (190), Expect = 2e-14 Identities = 44/130 (33%), Positives = 72/130 (55%) Frame = +3 Query: 180 VRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHL 359 V + Y + +GRG F +T + YA K I + + +E E+++++ + Sbjct: 93 VTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKY---REGREVCESELRVLRRV 149 Query: 360 SGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVC 539 NI++ +E + V++VMEL GGELFDRIIAKG ++ER A + + V++ V Sbjct: 150 R-HANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYL 208 Query: 540 HFMGVMHRDL 569 H +G+ HRDL Sbjct: 209 HALGITHRDL 218
>MYLK_MOUSE (Q6PDN3) Myosin light chain kinase, smooth muscle and non-muscle| isozymes (EC 2.7.11.18) (MLCK) [Contains: Telokin (Kinase-related protein) (KRP)] Length = 1941 Score = 77.8 bits (190), Expect = 2e-14 Identities = 48/140 (34%), Positives = 76/140 (54%), Gaps = 1/140 (0%) Frame = +3 Query: 153 TILGKQYEDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIR 332 T+ + V VY + + LG G+FG + E TG+ +A K K S +K++IR Sbjct: 1473 TVTVNTEQKVSDVYDIEERLGSGKFGQVFRLVEKKTGKIWAGKFF---KAYSAKEKDNIR 1529 Query: 333 REIQIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKG-HYSERAAATIC 509 +EI IM L P +V+ A+E+K ++ +V+E+ +GGELF+RII + +ER Sbjct: 1530 QEISIMNCLH-HPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYM 1588 Query: 510 RGVVNVVNVCHFMGVMHRDL 569 R + V H G++H DL Sbjct: 1589 RQISEGVEYIHKQGIVHLDL 1608
>CCAMK_PEA (Q6RET6) Calcium and calcium/calmodulin-dependent| serine/threonine-protein kinase (EC 2.7.11.17) (PsCCaMK) (Ps-SYM9) (Fragment) Length = 527 Score = 77.8 bits (190), Expect = 2e-14 Identities = 33/76 (43%), Positives = 52/76 (68%) Frame = +3 Query: 342 QIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVV 521 +I++++S PN+++ YED VH+V+ELC+GGELFDRI+A+ YSE A+T+ +V Sbjct: 105 RIVENVSPHPNVIDLYDVYEDTNGVHLVLELCSGGELFDRIVAQDKYSETEASTVVHQIV 164 Query: 522 NVVNVCHFMGVMHRDL 569 + H ++HRDL Sbjct: 165 AGLEAIHRANIIHRDL 180
>KS6A1_MOUSE (P18653) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 724 Score = 77.4 bits (189), Expect = 3e-14 Identities = 43/126 (34%), Positives = 63/126 (50%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y + + +G G + V C +T +YA K I K K D EI+I+ P Sbjct: 407 YVVKETIGVGSYSVCKRCVHKATNMEYAVKVIDK-------SKRDPSEEIEILLRYGQHP 459 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NI+ Y+D V++V EL GGEL D+I+ + +SER A+ + + V H G Sbjct: 460 NIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTISKTVEYLHSQG 519 Query: 552 VMHRDL 569 V+HRDL Sbjct: 520 VVHRDL 525 Score = 52.4 bits (124), Expect = 9e-07 Identities = 33/131 (25%), Positives = 70/131 (53%), Gaps = 3/131 (2%) Frame = +3 Query: 186 SVYSLGKELGRGQFGVTYLCTEIS---TGRQYACKSISKRKLVSKADKEDIRREIQIMQH 356 S + L K LG+G FG +L +++ +G YA K + K L + D+ + E I+ Sbjct: 60 SQFELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVR-DRVRTKMERDILAD 118 Query: 357 LSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNV 536 ++ P +V+ A++ +G ++++++ GG+LF R+ + ++E + ++ Sbjct: 119 VN-HPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDH 177 Query: 537 CHFMGVMHRDL 569 H +G+++RDL Sbjct: 178 LHSLGIIYRDL 188
>KS6A1_RAT (Q63531) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 77.4 bits (189), Expect = 3e-14 Identities = 43/126 (34%), Positives = 63/126 (50%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y + + +G G + V C +T +YA K I K K D EI+I+ P Sbjct: 418 YIVKETIGVGSYSVCKRCVHKATNMEYAVKVIDK-------SKRDPSEEIEILLRYGQHP 470 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NI+ Y+D V++V EL GGEL D+I+ + +SER A+ + + V H G Sbjct: 471 NIITLKDVYDDSKHVYLVTELMRGGELLDKILRQKFFSEREASFVLYTISKTVEYLHSQG 530 Query: 552 VMHRDL 569 V+HRDL Sbjct: 531 VVHRDL 536 Score = 51.6 bits (122), Expect = 2e-06 Identities = 33/131 (25%), Positives = 69/131 (52%), Gaps = 3/131 (2%) Frame = +3 Query: 186 SVYSLGKELGRGQFGVTYLCTEIS---TGRQYACKSISKRKLVSKADKEDIRREIQIMQH 356 S + L K LG+G FG +L +++ G YA K + K L + D+ + E I+ Sbjct: 60 SHFELLKVLGQGSFGKVFLVRKVTRPDNGHLYAMKVLKKATLKVR-DRVRTKMERDILAD 118 Query: 357 LSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNV 536 ++ P +V+ A++ +G ++++++ GG+LF R+ + ++E + ++ Sbjct: 119 VN-HPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDH 177 Query: 537 CHFMGVMHRDL 569 H +G+++RDL Sbjct: 178 LHSLGIIYRDL 188
>KPSH1_PINFU (Q4KTY1) Serine/threonine-protein kinase H1 homolog (EC 2.7.11.1)| Length = 415 Score = 77.4 bits (189), Expect = 3e-14 Identities = 48/140 (34%), Positives = 72/140 (51%), Gaps = 5/140 (3%) Frame = +3 Query: 165 KQYED-----VRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDI 329 K+Y D V + Y + +GRG F T + YA K I + + KE Sbjct: 66 KKYRDKFDPRVTAKYDIKALIGRGNFSKVVRVEHRVTKQPYAIKMIDRVQ-----GKEVF 120 Query: 330 RREIQIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATIC 509 E+ +++ + I++ +E K V++VMEL GGELFDRIIAKG ++ER A + Sbjct: 121 ESEVAVLRRVK-HSYIIQLIEVFETKDKVYMVMELATGGELFDRIIAKGSFTERDATRVL 179 Query: 510 RGVVNVVNVCHFMGVMHRDL 569 V++ V H +G+ HRDL Sbjct: 180 NMVLDGVKYLHGLGITHRDL 199
>KIC1_YEAST (P38692) Serine/threonine-protein kinase KIC1 (EC 2.7.11.1) (Kinase| that interacts with CDC31) (N-rich kinase 1) Length = 1080 Score = 77.4 bits (189), Expect = 3e-14 Identities = 47/132 (35%), Positives = 73/132 (55%), Gaps = 1/132 (0%) Frame = +3 Query: 177 DVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADK-EDIRREIQIMQ 353 DV S++ + +GRG+FGV Y + TGR YA K ++ L S +D+ ED++REIQ + Sbjct: 18 DVSSLFKRTEVIGRGKFGVVYKGYNVKTGRVYAIKVLN---LDSDSDEVEDVQREIQFLA 74 Query: 354 HLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVN 533 L NI + G+Y S+ ++ME CAGG L ++ G E+ I R ++ + Sbjct: 75 SLKQISNITRYYGSYLKDTSLWIIMEHCAGGSL-RSLLRPGKIDEKYIGVIMRELLVALK 133 Query: 534 VCHFMGVMHRDL 569 H V+HRD+ Sbjct: 134 CIHKDNVIHRDI 145
>KCC1_EMENI (Q00771) Calcium/calmodulin-dependent protein kinase (EC 2.7.11.17)| (CMPK) Length = 414 Score = 77.0 bits (188), Expect = 3e-14 Identities = 45/129 (34%), Positives = 75/129 (58%) Frame = +3 Query: 183 RSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLS 362 +S+Y G+ LG G +G+ + S+G+ A K I KR + + ++ + E+ ++Q L+ Sbjct: 20 KSLYRFGRTLGAGTYGIVREA-DCSSGK-VAVKIILKRNV--RGNERMVYDELDLLQKLN 75 Query: 363 GQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCH 542 P+IV F +E K ++V +L GGELFDRI G ++E+ A+ R V++ VN H Sbjct: 76 -HPHIVHFVDWFESKDKFYIVTQLATGGELFDRICEYGKFTEKDASQTIRQVLDAVNYLH 134 Query: 543 FMGVMHRDL 569 ++HRDL Sbjct: 135 QRNIVHRDL 143
>SAPK2_ORYSA (Q84TC6) Serine/threonine-protein kinase SAPK2 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 2) Length = 339 Score = 77.0 bits (188), Expect = 3e-14 Identities = 47/127 (37%), Positives = 70/127 (55%), Gaps = 1/127 (0%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLS-GQ 368 Y + K++G G FGV L ++ T +A K I + + + E+++REI M H S Sbjct: 4 YEVIKDIGSGNFGVAKLVRDVRTKELFAVKFIERGQKID----ENVQREI--MNHRSLRH 57 Query: 369 PNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFM 548 PNIV F + +VME AGGELF+RI + G +SE A + +++ V+ CH M Sbjct: 58 PNIVRFKEVVLTPTHLAIVMEYAAGGELFERICSAGRFSEDEARFFFQQLISGVSYCHSM 117 Query: 549 GVMHRDL 569 + HRDL Sbjct: 118 QICHRDL 124
>KCCS_MALDO (Q07250) Calcium/calmodulin-dependent serine/threonine-protein| kinase (EC 2.7.11.17) Length = 415 Score = 76.6 bits (187), Expect = 4e-14 Identities = 38/103 (36%), Positives = 62/103 (60%), Gaps = 3/103 (2%) Frame = +3 Query: 270 YACKSISKRKLVSKAD---KEDIRREIQIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCA 440 +A + RK VS ++ +I +I++++S PN+++ YED+ VH+V+ELC+ Sbjct: 72 FAAAAFQTRKQVSISNVLLTNEILVMRKIVENVSPHPNVIDLYDVYEDENGVHLVLELCS 131 Query: 441 GGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMGVMHRDL 569 GGELFDRI+ + YSE AA + R + + H ++HRDL Sbjct: 132 GGELFDRIVKQERYSEVGAAAVVRQIAQGLAALHRSNIVHRDL 174
>SN1L1_MOUSE (Q60670) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (HRT-20) (Myocardial SNF1-like kinase) Length = 779 Score = 76.6 bits (187), Expect = 4e-14 Identities = 45/126 (35%), Positives = 68/126 (53%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y + + LG+G F V L T Q A K I K +L S ++ E I RE+Q+M+ L+ P Sbjct: 27 YDVERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDS-SNLEKIYREVQLMKLLN-HP 84 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NI++ E K +++V E GE+FD + + GH SE A +++ V CH Sbjct: 85 NIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARQKFWQILSAVEYCHNHH 144 Query: 552 VMHRDL 569 ++HRDL Sbjct: 145 IVHRDL 150
>SN1L1_RAT (Q9R1U5) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (Salt-inducible protein kinase) (Protein kinase KID2) Length = 776 Score = 76.6 bits (187), Expect = 4e-14 Identities = 45/126 (35%), Positives = 68/126 (53%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y + + LG+G F V L T Q A K I K +L S ++ E I RE+Q+M+ L+ P Sbjct: 27 YDVERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDS-SNLEKIYREVQLMKLLN-HP 84 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NI++ E K +++V E GE+FD + + GH SE A +++ V CH Sbjct: 85 NIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHNHH 144 Query: 552 VMHRDL 569 ++HRDL Sbjct: 145 IVHRDL 150
>DCAK2_MOUSE (Q6PGN3) Serine/threonine-protein kinase DCAMKL2 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 2) Length = 756 Score = 76.6 bits (187), Expect = 4e-14 Identities = 41/126 (32%), Positives = 66/126 (52%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y +GK +G G F V C + TG+++A K I K K K + I E+ I++ + P Sbjct: 393 YRIGKVIGDGNFAVVKECVDRYTGKEFALKIIDKAKCCGK--EHLIENEVSILRRVK-HP 449 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NI+ E + +VMEL GG+LFD I + Y+ER + + + N + H + Sbjct: 450 NIIMLVEEMETATDLFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHSLS 509 Query: 552 VMHRDL 569 ++HRD+ Sbjct: 510 IVHRDI 515
>MYLK_BOVIN (Q28824) Myosin light chain kinase, smooth muscle (EC 2.7.11.18)| (MLCK) [Contains: Telokin] Length = 1176 Score = 75.9 bits (185), Expect = 8e-14 Identities = 47/140 (33%), Positives = 75/140 (53%), Gaps = 1/140 (0%) Frame = +3 Query: 153 TILGKQYEDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIR 332 T+ + V Y + + LG G+FG + E TG+ +A K K S +KE+IR Sbjct: 712 TVTVNTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTGKIWAGKFF---KAYSAKEKENIR 768 Query: 333 REIQIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKG-HYSERAAATIC 509 +EI IM L P +V+ A+E+K ++ +V+E+ +GGELF+RII + +ER Sbjct: 769 QEISIMNCLH-HPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYM 827 Query: 510 RGVVNVVNVCHFMGVMHRDL 569 + + V H G++H DL Sbjct: 828 KQISEGVEYIHKQGIVHLDL 847
>AURKB_RAT (O55099) Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-| and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora-B) Length = 343 Score = 75.9 bits (185), Expect = 8e-14 Identities = 38/126 (30%), Positives = 69/126 (54%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 + +G+ LG+G+FG YL E + A K + K ++ + + +RREI+I HL P Sbjct: 80 FEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQIEKEGVEHQLRREIEIQAHLK-HP 138 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NI++ + D+ +++++E GEL+ + G + E+ ATI + + + CH Sbjct: 139 NILQLYNYFYDQQRIYLILEYAPRGELYKELQKSGTFDEQRTATIMEELSDALMYCHKKK 198 Query: 552 VMHRDL 569 V+HRD+ Sbjct: 199 VIHRDI 204
>SN1L2_CHICK (Q9IA88) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Qin-induced kinase) Length = 798 Score = 75.9 bits (185), Expect = 8e-14 Identities = 44/126 (34%), Positives = 67/126 (53%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y + + LG+G F V L T Q A K I K +L ++ E I RE+QIM+ L+ P Sbjct: 26 YDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRL-DPSNLEKIYREVQIMKLLN-HP 83 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 +I++ E K +++V E GE+FD + + GH SE A +++ V CH Sbjct: 84 HIIKLYQVMETKDMLYIVTEFAKNGEMFDHLTSNGHLSESEARKKFWQILSAVEYCHSHH 143 Query: 552 VMHRDL 569 ++HRDL Sbjct: 144 IVHRDL 149
>STK33_HUMAN (Q9BYT3) Serine/threonine-protein kinase 33 (EC 2.7.11.1)| Length = 514 Score = 75.9 bits (185), Expect = 8e-14 Identities = 40/130 (30%), Positives = 72/130 (55%) Frame = +3 Query: 180 VRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHL 359 + +Y+ G+ LG+G FG+ T+ T ++A K ++K K S A K + RE+ I++ + Sbjct: 112 IEEIYTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKL-LEREVNILKSV 170 Query: 360 SGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVC 539 + +I+ +E +++VMELC GEL + + KGH+SE I + + + + Sbjct: 171 KHE-HIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYL 229 Query: 540 HFMGVMHRDL 569 H ++HRDL Sbjct: 230 HNNDIVHRDL 239
>MELK_HUMAN (Q14680) Maternal embryonic leucine zipper kinase (EC 2.7.11.1)| (hMELK) (Protein kinase PK38) (hPK38) Length = 651 Score = 75.5 bits (184), Expect = 1e-13 Identities = 46/135 (34%), Positives = 67/135 (49%) Frame = +3 Query: 165 KQYEDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQ 344 K Y+++ Y L + +G G F L I TG A K + K L S D I+ EI+ Sbjct: 2 KDYDELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGS--DLPRIKTEIE 59 Query: 345 IMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVN 524 +++L Q +I + E + +V+E C GGELFD II++ SE + R +V+ Sbjct: 60 ALKNLRHQ-HICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVS 118 Query: 525 VVNVCHFMGVMHRDL 569 V H G HRDL Sbjct: 119 AVAYVHSQGYAHRDL 133
>KPSH1_BRARE (Q501V0) Serine/threonine-protein kinase H1 homolog (EC 2.7.11.1)| Length = 422 Score = 75.1 bits (183), Expect = 1e-13 Identities = 44/130 (33%), Positives = 69/130 (53%) Frame = +3 Query: 180 VRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHL 359 V + Y + +GRG F ST + YA K I R + +E E+ +++ + Sbjct: 92 VTAKYDIKALIGRGSFSRVVRVEHRSTRQPYAIKMIETRY---REGREVCESELCVLRRV 148 Query: 360 SGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVC 539 NI++ +E V++VMEL GGELFDRII +G ++ER A + + V++ V Sbjct: 149 R-HTNIIQLMEVFETAERVYMVMELATGGELFDRIITRGSFTERDATRVLQMVLDGVKYL 207 Query: 540 HFMGVMHRDL 569 H +G+ HRDL Sbjct: 208 HTLGITHRDL 217
>MKNK2_XENTR (Q66I46) MAP kinase-interacting serine/threonine-protein kinase 2| (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (Mnk2) Length = 466 Score = 75.1 bits (183), Expect = 1e-13 Identities = 42/141 (29%), Positives = 75/141 (53%), Gaps = 1/141 (0%) Frame = +3 Query: 150 DTILGKQYEDVRSVYSLGKE-LGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKED 326 D+ G+ +ED+ Y L +E LG G + C + T ++YA K I KR S++ Sbjct: 72 DSFTGR-FEDM---YQLQQEILGEGAYAKVQSCINLITNKEYAVKIIEKRPGHSRSR--- 124 Query: 327 IRREIQIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATI 506 + RE++++ G N++E +E++ ++V E GG + + I + H++ER A+ + Sbjct: 125 VFREVEMLYQCQGHSNVLELIEFFEEEDKFYLVFEKMCGGSILNHIHRRRHFNEREASFV 184 Query: 507 CRGVVNVVNVCHFMGVMHRDL 569 R + +N H G+ HRDL Sbjct: 185 VRDIAEALNYLHNKGIAHRDL 205
>CDS1_SCHPO (Q09170) Serine/threonine-protein kinase cds1 (EC 2.7.11.1)| (Checkpoint kinase cds1) Length = 460 Score = 75.1 bits (183), Expect = 1e-13 Identities = 44/132 (33%), Positives = 71/132 (53%), Gaps = 4/132 (3%) Frame = +3 Query: 186 SVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLV----SKADKEDIRREIQIMQ 353 S Y + + LG G F V L E+++G+ YA K I+KRK++ K E +REI I++ Sbjct: 165 SHYEIIRTLGSGTFAVVKLAVEVNSGKWYAIKIINKRKILLTSSEKRATEMFQREIDILK 224 Query: 354 HLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVN 533 L P +V+ +E+ + +VME GG+L D +IA G E+ + + ++ + Sbjct: 225 SLH-HPGVVQCHEIFENDDELFIVMEYVEGGDLMDFLIANGSIDEQDCKPLLKQLLETLL 283 Query: 534 VCHFMGVMHRDL 569 H GV HRD+ Sbjct: 284 HLHKQGVTHRDI 295
>SN1L1_HUMAN (P57059) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) Length = 783 Score = 75.1 bits (183), Expect = 1e-13 Identities = 44/126 (34%), Positives = 68/126 (53%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y + + LG+G F V L T Q A K I K +L S ++ E I RE+Q+M+ L+ P Sbjct: 27 YDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDS-SNLEKIYREVQLMKLLN-HP 84 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 +I++ E K +++V E GE+FD + + GH SE A +++ V CH Sbjct: 85 HIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHDHH 144 Query: 552 VMHRDL 569 ++HRDL Sbjct: 145 IVHRDL 150
>SAPK1_ORYSA (Q75LR7) Serine/threonine-protein kinase SAPK1 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 1) Length = 342 Score = 74.7 bits (182), Expect = 2e-13 Identities = 46/127 (36%), Positives = 68/127 (53%), Gaps = 1/127 (0%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLS-GQ 368 Y + +++G G FGV L +++T +A K I + + E ++REI M H S Sbjct: 4 YEVMRDIGSGNFGVAKLVRDVATNHLFAVKFIERGLKID----EHVQREI--MNHRSLKH 57 Query: 369 PNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFM 548 PNI+ F + +VME AGGELF+RI G +SE A + +++ V+ CH M Sbjct: 58 PNIIRFKEVVLTPTHLAIVMEYAAGGELFERICNAGRFSEDEARFFFQQLISGVSYCHSM 117 Query: 549 GVMHRDL 569 V HRDL Sbjct: 118 QVCHRDL 124
>KS6A1_HUMAN (Q15418) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 74.7 bits (182), Expect = 2e-13 Identities = 42/126 (33%), Positives = 62/126 (49%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y + + +G G + C +T +YA K I K K D EI+I+ P Sbjct: 418 YVVKETIGVGSYSECKRCVHKATNMEYAVKVIDK-------SKRDPSEEIEILLRYGQHP 470 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NI+ Y+D V++V EL GGEL D+I+ + +SER A+ + + V H G Sbjct: 471 NIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTIGKTVEYLHSQG 530 Query: 552 VMHRDL 569 V+HRDL Sbjct: 531 VVHRDL 536 Score = 52.0 bits (123), Expect = 1e-06 Identities = 33/131 (25%), Positives = 70/131 (53%), Gaps = 3/131 (2%) Frame = +3 Query: 186 SVYSLGKELGRGQFGVTYLCTEIS---TGRQYACKSISKRKLVSKADKEDIRREIQIMQH 356 S + L K LG+G FG +L +++ +G YA K + K L + D+ + E I+ Sbjct: 60 SHFELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVR-DRVRTKMERDILAD 118 Query: 357 LSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNV 536 ++ P +V+ A++ +G ++++++ GG+LF R+ + ++E + ++ Sbjct: 119 VN-HPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDH 177 Query: 537 CHFMGVMHRDL 569 H +G+++RDL Sbjct: 178 LHSLGIIYRDL 188
>CIPK1_ORYSA (Q6X4A2) CIPK-like protein 1 (EC 2.7.11.1) (OsCK1)| Length = 449 Score = 74.7 bits (182), Expect = 2e-13 Identities = 43/126 (34%), Positives = 57/126 (45%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y LG+ +G G F A K + K K+ E IRREI M+ L P Sbjct: 20 YELGRTIGEGTFAKVRFAKNTENDEPVAIKILDKEKVQKHRLVEQIRREICTMK-LVKHP 78 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 N+V K + +V+E GGELF+ I G E A + ++N V+ CH G Sbjct: 79 NVVRLFEVMGSKARIFIVLEYVTGGELFEIIATNGRLKEEEARKYFQQLINAVDYCHSRG 138 Query: 552 VMHRDL 569 V HRDL Sbjct: 139 VYHRDL 144
>ZYG1_CAEEL (Q9GT24) Probable serine/threonine-protein kinase zyg-1 (EC| 2.7.11.1) (Zygote defective protein 1) Length = 706 Score = 74.3 bits (181), Expect = 2e-13 Identities = 45/128 (35%), Positives = 65/128 (50%) Frame = +3 Query: 186 SVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSG 365 S YS KE+G+G FGV Y + G + A K I K K K + EIQ M+ L Sbjct: 11 SAYSHLKEIGKGGFGVVY-AAQRENGEKVAIKRIDK-----KVPKNRVWTEIQTMKELKK 64 Query: 366 QPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHF 545 +VEF + + G ++VMELC GG L + G + A + R +++ V+ H Sbjct: 65 SKYVVEFYEDFVEDGYTYIVMELCEGGSLQAYVREHGALDDATAVHVLRQLISAVSFMHR 124 Query: 546 MGVMHRDL 569 + V+HRDL Sbjct: 125 VNVIHRDL 132
>MKNK2_XENLA (Q6P431) MAP kinase-interacting serine/threonine-protein kinase 2| (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (Mnk2) Length = 467 Score = 74.3 bits (181), Expect = 2e-13 Identities = 38/128 (29%), Positives = 68/128 (53%), Gaps = 1/128 (0%) Frame = +3 Query: 189 VYSLGKE-LGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSG 365 +Y L +E LG G + C + T ++YA K I KR S++ + RE++++ G Sbjct: 81 MYQLQQEILGEGAYAKVQSCINLITNKEYAVKIIEKRPGHSRSR---VFREVEMLYQCQG 137 Query: 366 QPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHF 545 N++E +E++ ++V E GG + + I + H++ER A+ + R + +N H Sbjct: 138 HSNVLELIEFFEEEDKFYLVFEKMCGGSILNHIHRRRHFNEREASFVVRDIAEALNYLHN 197 Query: 546 MGVMHRDL 569 G+ HRDL Sbjct: 198 KGIAHRDL 205
>STK6L_XENLA (Q91819) Serine/threonine-protein kinase Eg2-like (EC 2.7.11.1)| (p46XlEg22) Length = 408 Score = 74.3 bits (181), Expect = 2e-13 Identities = 39/136 (28%), Positives = 70/136 (51%) Frame = +3 Query: 162 GKQYEDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREI 341 GK+ + + +G+ LG+G+FG YL E + A K + K +L + +RRE+ Sbjct: 130 GKKKQWCLEDFEIGRPLGKGKFGNVYLARERESKFILALKVLFKSQLEKAGVEHQLRREV 189 Query: 342 QIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVV 521 +I HL PNI+ G + D V+++++ GGELF + + ++ +A + + Sbjct: 190 EIQSHLR-HPNILRLYGYFHDASRVYLILDYAPGGELFRELQKCTRFDDQRSALYIKQLA 248 Query: 522 NVVNVCHFMGVMHRDL 569 + CH V+HRD+ Sbjct: 249 EALLYCHSKKVIHRDI 264
>STK6_XENLA (Q91820) Serine/threonine-protein kinase Eg2 (EC 2.7.11.1) (pEg2)| (p46Eg265) Length = 407 Score = 74.3 bits (181), Expect = 2e-13 Identities = 39/136 (28%), Positives = 70/136 (51%) Frame = +3 Query: 162 GKQYEDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREI 341 GK+ + + +G+ LG+G+FG YL E + A K + K +L + +RRE+ Sbjct: 130 GKKKQWCLEDFEIGRPLGKGKFGNVYLARERESKFILALKVLFKSQLEKAGVEHQLRREV 189 Query: 342 QIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVV 521 +I HL PNI+ G + D V+++++ GGELF + + ++ +A + + Sbjct: 190 EIQSHLR-HPNILRLYGYFHDASRVYLILDYAPGGELFRELQKCTRFDDQRSAMYIKQLA 248 Query: 522 NVVNVCHFMGVMHRDL 569 + CH V+HRD+ Sbjct: 249 EALLYCHSKKVIHRDI 264
>IPL1_ASHGO (Q755C4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 367 Score = 73.9 bits (180), Expect = 3e-13 Identities = 34/126 (26%), Positives = 69/126 (54%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 + +GK LG+G+FG Y I +G A K++ K+ ++ ++ RRE++I L P Sbjct: 109 FEIGKVLGKGKFGRVYCVRHIESGFVCALKAMEKKDIIQYNIEKQFRREVEIQSSLR-HP 167 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 N+ + G + D+ V+++ME GEL+ + + H+++ A+ + + ++ H Sbjct: 168 NLTQLYGYFHDEKRVYLLMEYLVNGELYKHLKGRSHFNDVVASYYVYQMADALDYMHERN 227 Query: 552 VMHRDL 569 ++HRD+ Sbjct: 228 ILHRDI 233
>SAPK9_ORYSA (Q75V57) Serine/threonine-protein kinase SAPK9 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 9) Length = 361 Score = 73.9 bits (180), Expect = 3e-13 Identities = 47/127 (37%), Positives = 69/127 (54%), Gaps = 1/127 (0%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLS-GQ 368 Y L KE+G G FGV L ++G A K I + + + E+++REI + H S Sbjct: 22 YELVKEIGSGNFGVARLMRNRASGDLVAVKYIDRGEKID----ENVQREI--INHRSLRH 75 Query: 369 PNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFM 548 PNI+ F + +VME +GGELF+RI + G +SE A + +++ V+ CH M Sbjct: 76 PNIIRFKEVILTPTHLAIVMEYASGGELFERICSAGRFSEDEARFFFQQLISGVSYCHSM 135 Query: 549 GVMHRDL 569 V HRDL Sbjct: 136 QVCHRDL 142
>MYLK_HUMAN (Q15746) Myosin light chain kinase, smooth muscle and non-muscle| isozymes (EC 2.7.11.18) (MLCK) [Contains: Telokin (Kinase-related protein) (KRP)] Length = 1914 Score = 73.9 bits (180), Expect = 3e-13 Identities = 46/133 (34%), Positives = 72/133 (54%), Gaps = 1/133 (0%) Frame = +3 Query: 174 EDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQ 353 + V Y + + LG G+FG + E T + +A K K S +KE+IR+EI IM Sbjct: 1458 QKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFF---KAYSAKEKENIRQEISIMN 1514 Query: 354 HLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKG-HYSERAAATICRGVVNVV 530 L P +V+ A+E+K ++ +V+E+ +GGELF+RII + +ER R + V Sbjct: 1515 CLH-HPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGV 1573 Query: 531 NVCHFMGVMHRDL 569 H G++H DL Sbjct: 1574 EYIHKQGIVHLDL 1586
>MELK_MOUSE (Q61846) Maternal embryonic leucine zipper kinase (EC 2.7.11.1)| (Protein kinase PK38) (mPK38) Length = 643 Score = 73.9 bits (180), Expect = 3e-13 Identities = 44/135 (32%), Positives = 66/135 (48%) Frame = +3 Query: 165 KQYEDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQ 344 K Y+++ Y L + +G G F L + TG A K + K L S D ++ EI Sbjct: 2 KDYDELLKYYELYETIGTGGFAKVKLACHVLTGEMVAIKIMDKNALGS--DLPRVKTEID 59 Query: 345 IMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVN 524 ++ L Q +I + E K + +V+E C GGELFD II++ SE + R +++ Sbjct: 60 ALKSLRHQ-HICQLYHVLETKNKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQILS 118 Query: 525 VVNVCHFMGVMHRDL 569 V H G HRDL Sbjct: 119 AVAYVHSQGYAHRDL 133
>KS6A4_HUMAN (O75676) Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (Ribosomal protein kinase B) (RSKB) Length = 772 Score = 73.9 bits (180), Expect = 3e-13 Identities = 47/142 (33%), Positives = 77/142 (54%), Gaps = 2/142 (1%) Frame = +3 Query: 150 DTILGKQYE-DVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKED 326 D+ +QYE D+R LG+G F V C + +G+++A K +S+R + + Sbjct: 401 DSPFFQQYELDLRE-----PALGQGSFSVCRRCRQRQSGQEFAVKILSRRL------EAN 449 Query: 327 IRREIQIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATI 506 +RE+ ++ PN+V + D+ ++V+EL GGEL + I K H+SE A+ I Sbjct: 450 TQREVAALRLCQSHPNVVNLHEVHHDQLHTYLVLELLRGGELLEHIRKKRHFSESEASQI 509 Query: 507 CRGVVNVVNVCH-FMGVMHRDL 569 R +V+ V+ H GV+HRDL Sbjct: 510 LRSLVSAVSFMHEEAGVVHRDL 531 Score = 57.4 bits (137), Expect = 3e-08 Identities = 33/130 (25%), Positives = 65/130 (50%), Gaps = 4/130 (3%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEIS---TGRQYACKSISKRKLVSKAD-KEDIRREIQIMQHL 359 + L K LG G +G +L + G+ YA K + K LV +A +E R E +++ + Sbjct: 33 FELLKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAALVQRAKTQEHTRTERSVLELV 92 Query: 360 SGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVC 539 P +V A++ +H++++ +GGE+F + + ++ E +V + Sbjct: 93 RQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYGGEIVLALEHL 152 Query: 540 HFMGVMHRDL 569 H +G+++RDL Sbjct: 153 HKLGIIYRDL 162
>CCAMK_LILLO (Q43531) Calcium and calcium/calmodulin-dependent| serine/threonine-protein kinase (EC 2.7.11.17) (LlCCaMK) Length = 520 Score = 73.6 bits (179), Expect = 4e-13 Identities = 32/76 (42%), Positives = 50/76 (65%) Frame = +3 Query: 342 QIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVV 521 +I++ +S PN++ YED VH+V+ELC+GGELFDRI+A+ YSE AA + + + Sbjct: 93 RIVEDVSPHPNVIHLHDVYEDANGVHLVLELCSGGELFDRIVAQDRYSESEAAEVVQQIA 152 Query: 522 NVVNVCHFMGVMHRDL 569 + + H ++HRDL Sbjct: 153 SGLAALHKSTIIHRDL 168
>AURKB_MOUSE (O70126) Serine/threonine-protein kinase 12 (EC 2.7.11.1)| (Aurora-related kinase 2) (Serine/threonine-protein kinase 5) (STK-1) (Aurora-B) Length = 345 Score = 73.6 bits (179), Expect = 4e-13 Identities = 37/126 (29%), Positives = 68/126 (53%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 + +G+ LG+G+FG YL E + A K + K ++ + + +RREI+I HL P Sbjct: 82 FEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQIEKEGVEHQLRREIEIQAHLK-HP 140 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NI++ + D+ +++++E GEL+ + + E+ ATI + + + CH Sbjct: 141 NILQLYNYFYDQQRIYLILEYAPRGELYKELQKSRTFDEQRTATIMEELSDALTYCHKKK 200 Query: 552 VMHRDL 569 V+HRD+ Sbjct: 201 VIHRDI 206
>SNF1_CANGA (Q00372) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 612 Score = 72.8 bits (177), Expect = 6e-13 Identities = 42/126 (33%), Positives = 68/126 (53%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y + K LG G FG L ++TG++ A K I+K+ L + I REI ++ L P Sbjct: 39 YQIVKTLGEGSFGKVKLAYHVTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLR-HP 97 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 +I++ + K + +V+E AG ELFD I+ + SE+ A + +++ V CH Sbjct: 98 HIIKLYDVIKSKDEIIMVIEY-AGNELFDYIVQRNKMSEQEARRFFQQIISAVEYCHRHK 156 Query: 552 VMHRDL 569 ++HRDL Sbjct: 157 IVHRDL 162
>MYLK_RABIT (P29294) Myosin light chain kinase, smooth muscle (EC 2.7.11.18)| (MLCK) [Contains: Telokin] Length = 1147 Score = 72.8 bits (177), Expect = 6e-13 Identities = 47/140 (33%), Positives = 73/140 (52%), Gaps = 1/140 (0%) Frame = +3 Query: 153 TILGKQYEDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIR 332 T+ + V Y + + LG G+FG + E TG+ +A K K S +KE+I Sbjct: 683 TVTVNTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTGKIWAGKFF---KAYSAKEKENIP 739 Query: 333 REIQIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKG-HYSERAAATIC 509 EI IM L P +V+ A+E+K ++ +V+E+ +GGELF+RII + +ER Sbjct: 740 AEIGIMNCLH-HPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYM 798 Query: 510 RGVVNVVNVCHFMGVMHRDL 569 R + V H G++H DL Sbjct: 799 RQISEGVEYIHKQGIVHLDL 818
>AURKB_HUMAN (Q96GD4) Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-| and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (Aurora-related kinase 2) (STK-1) (Aurora-B) Length = 344 Score = 72.4 bits (176), Expect = 8e-13 Identities = 37/126 (29%), Positives = 67/126 (53%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 + +G+ LG+G+FG YL E + A K + K ++ + + +RREI+I HL P Sbjct: 77 FEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLH-HP 135 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NI+ + D+ +++++E GEL+ + + E+ ATI + + + CH Sbjct: 136 NILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKK 195 Query: 552 VMHRDL 569 V+HRD+ Sbjct: 196 VIHRDI 201
>NEK1_HUMAN (Q96PY6) Serine/threonine-protein kinase Nek1 (EC 2.7.11.1)| (NimA-related protein kinase 1) (NY-REN-55 antigen) Length = 1258 Score = 72.0 bits (175), Expect = 1e-12 Identities = 43/128 (33%), Positives = 73/128 (57%), Gaps = 6/128 (4%) Frame = +3 Query: 204 KELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQPNIVE 383 +++G G FG L GRQY K I+ ++ SK ++E+ RRE+ ++ ++ PNIV+ Sbjct: 8 QKIGEGSFGKAILVKSTEDGRQYVIKEINISRMSSK-EREESRREVAVLANMK-HPNIVQ 65 Query: 384 FCGAYEDKGSVHVVMELCAGGELFDRIIA-KGHYSERAA-----ATICRGVVNVVNVCHF 545 + ++E+ GS+++VM+ C GG+LF RI A KG + IC + +V H Sbjct: 66 YRESFEENGSLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWFVQICLALKHV----HD 121 Query: 546 MGVMHRDL 569 ++HRD+ Sbjct: 122 RKILHRDI 129
>IPL1_YEAST (P38991) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) (Increase-in-ploidy protein 1) Length = 367 Score = 72.0 bits (175), Expect = 1e-12 Identities = 36/126 (28%), Positives = 69/126 (54%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 + LGK+LG+G+FG Y STG A K + K +++ ++ RRE++I L+ P Sbjct: 104 FELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKYNLQKQFRREVEIQTSLN-HP 162 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 N+ + G + D+ V+++ME GE++ + G +++ A+ + N ++ H Sbjct: 163 NLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALDYMHKKN 222 Query: 552 VMHRDL 569 ++HRD+ Sbjct: 223 IIHRDI 228
>CSKP_RAT (Q62915) Peripheral plasma membrane protein CASK (EC 2.7.11.1)| (Calcium/calmodulin-dependent serine protein kinase) Length = 909 Score = 72.0 bits (175), Expect = 1e-12 Identities = 42/133 (31%), Positives = 65/133 (48%), Gaps = 6/133 (4%) Frame = +3 Query: 189 VYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSK--ADKEDIRREIQIMQHLS 362 VY L + +G+G F V C TG+Q+A K + K S ED++RE I H+ Sbjct: 11 VYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASIC-HML 69 Query: 363 GQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGH----YSERAAATICRGVVNVV 530 P+IVE Y G +++V E G +L I+ + YSE A+ R ++ + Sbjct: 70 KHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEAL 129 Query: 531 NVCHFMGVMHRDL 569 CH ++HRD+ Sbjct: 130 RYCHDNNIIHRDV 142
>CSKP_MOUSE (O70589) Peripheral plasma membrane protein CASK (EC 2.7.11.1)| (Calcium/calmodulin-dependent serine protein kinase) Length = 924 Score = 72.0 bits (175), Expect = 1e-12 Identities = 42/133 (31%), Positives = 65/133 (48%), Gaps = 6/133 (4%) Frame = +3 Query: 189 VYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSK--ADKEDIRREIQIMQHLS 362 VY L + +G+G F V C TG+Q+A K + K S ED++RE I H+ Sbjct: 11 VYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASIC-HML 69 Query: 363 GQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGH----YSERAAATICRGVVNVV 530 P+IVE Y G +++V E G +L I+ + YSE A+ R ++ + Sbjct: 70 KHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEAL 129 Query: 531 NVCHFMGVMHRDL 569 CH ++HRD+ Sbjct: 130 RYCHDNNIIHRDV 142
>CSKP_HUMAN (O14936) Peripheral plasma membrane protein CASK (EC 2.7.11.1)| (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog) Length = 926 Score = 72.0 bits (175), Expect = 1e-12 Identities = 42/133 (31%), Positives = 65/133 (48%), Gaps = 6/133 (4%) Frame = +3 Query: 189 VYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSK--ADKEDIRREIQIMQHLS 362 VY L + +G+G F V C TG+Q+A K + K S ED++RE I H+ Sbjct: 11 VYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASIC-HML 69 Query: 363 GQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGH----YSERAAATICRGVVNVV 530 P+IVE Y G +++V E G +L I+ + YSE A+ R ++ + Sbjct: 70 KHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEAL 129 Query: 531 NVCHFMGVMHRDL 569 CH ++HRD+ Sbjct: 130 RYCHDNNIIHRDV 142
>SAPK7_ORYSA (Q7XQP4) Serine/threonine-protein kinase SAPK7 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 7) Length = 359 Score = 72.0 bits (175), Expect = 1e-12 Identities = 48/127 (37%), Positives = 64/127 (50%), Gaps = 1/127 (0%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLS-GQ 368 Y L K++G G FGV L T A K I + + E++ REI + H S Sbjct: 4 YELLKDIGAGNFGVARLMRNKETKELVAMKYIPRGLKID----ENVAREI--INHRSLRH 57 Query: 369 PNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFM 548 PNI+ F + +VME AGGELFDRI G +SE A + ++ V+ CHFM Sbjct: 58 PNIIRFKEVVVTPTHLAIVMEYAAGGELFDRICNAGRFSEDEARYFFQQLICGVSYCHFM 117 Query: 549 GVMHRDL 569 + HRDL Sbjct: 118 QICHRDL 124
>STK6_HUMAN (O14965) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1) (Aurora-related kinase 1) (hARK1) (Aurora-A) (Breast-tumor-amplified kinase) Length = 403 Score = 72.0 bits (175), Expect = 1e-12 Identities = 37/126 (29%), Positives = 65/126 (51%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 + +G+ LG+G+FG YL E + A K + K +L + +RRE++I HL P Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLR-HP 191 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NI+ G + D V++++E G ++ + + E+ AT + N ++ CH Sbjct: 192 NILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKR 251 Query: 552 VMHRDL 569 V+HRD+ Sbjct: 252 VIHRDI 257
>KCC1_METAN (O14408) Calcium/calmodulin-dependent protein kinase (EC 2.7.11.17)| Length = 382 Score = 71.6 bits (174), Expect = 1e-12 Identities = 44/131 (33%), Positives = 73/131 (55%) Frame = +3 Query: 177 DVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQH 356 D +S Y G+ LG G +GV S + A K I K+ + K +++ + E+ ++Q Sbjct: 18 DKKSKYKFGRTLGAGTYGVVREADGPSG--KVAIKIILKKNV--KGNEKMVYAELDMLQR 73 Query: 357 LSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNV 536 L+ P+IV+F +E + ++V +L GGELFDRI +G ++E A+ R ++ V+ Sbjct: 74 LT-HPHIVKFVDWFESRDKFYIVTQLATGGELFDRICDQGKFTEVDASQTIRQIMTAVDY 132 Query: 537 CHFMGVMHRDL 569 H V+HRDL Sbjct: 133 LHDNDVVHRDL 143
>SAPK6_ORYSA (Q6ZI44) Serine/threonine-protein kinase SAPK6 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 6) Length = 365 Score = 71.6 bits (174), Expect = 1e-12 Identities = 47/127 (37%), Positives = 65/127 (51%), Gaps = 1/127 (0%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLS-GQ 368 Y L K++G G FGV L T A K I + + E++ REI + H S Sbjct: 4 YELLKDIGSGNFGVARLMRNRETKELVAMKYIPRGLKID----ENVAREI--INHRSLRH 57 Query: 369 PNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFM 548 PNI+ F + +VME AGGELFDRI + G +SE + + ++ V+ CHFM Sbjct: 58 PNIIRFKEVVLTPTHLAIVMEYAAGGELFDRICSAGRFSEDESRYFFQQLICGVSYCHFM 117 Query: 549 GVMHRDL 569 + HRDL Sbjct: 118 QICHRDL 124
>KSG1_SCHPO (Q12701) Serine/threonine-protein kinase ksg1 (EC 2.7.11.1)| Length = 592 Score = 71.6 bits (174), Expect = 1e-12 Identities = 38/128 (29%), Positives = 66/128 (51%) Frame = +3 Query: 186 SVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSG 365 S + G+ LG G + TE ST R+YA K + KR ++ + ++ + E + + LS Sbjct: 97 SDFKFGEILGEGSYSTVLTATENSTKREYAIKVLDKRHIIKEKKEKYVNIEKEALCILSK 156 Query: 366 QPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHF 545 P ++ ++D +++ V+ L GEL D I G ++E A +V+ ++ H Sbjct: 157 HPGFIKLFYTFQDAHNLYFVLSLARNGELLDYINKLGRFNEICAQYYAALIVDSIDYMHG 216 Query: 546 MGVMHRDL 569 GV+HRDL Sbjct: 217 RGVIHRDL 224
>STK6_RAT (P59241) Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Aurora-A)| (ratAurA) Length = 397 Score = 71.2 bits (173), Expect = 2e-12 Identities = 37/126 (29%), Positives = 65/126 (51%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 + +G+ LG+G+FG YL E + A K + K +L + +RRE++I HL P Sbjct: 126 FDIGRPLGKGKFGNVYLAREKQSKFILALKVLFKVQLEKAGVEHQLRREVEIQSHLR-HP 184 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NI+ G + D V++++E G ++ + + E+ AT + N ++ CH Sbjct: 185 NILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKR 244 Query: 552 VMHRDL 569 V+HRD+ Sbjct: 245 VIHRDI 250
>STK6_MOUSE (P97477) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Aurora-family kinase 1) (Aurora/IPL1-related kinase 1) (Ipl1- and aurora-related kinase 1) (Aurora-A) (Serine/threonine-protein kinase Ayk1) Length = 395 Score = 71.2 bits (173), Expect = 2e-12 Identities = 37/126 (29%), Positives = 65/126 (51%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 + +G+ LG+G+FG YL E + A K + K +L + +RRE++I HL P Sbjct: 124 FDIGRPLGKGKFGNVYLARERQSKFILALKVLFKTQLEKANVEHQLRREVEIQSHLR-HP 182 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NI+ G + D V++++E G ++ + + E+ AT + N ++ CH Sbjct: 183 NILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKR 242 Query: 552 VMHRDL 569 V+HRD+ Sbjct: 243 VIHRDI 248
>SNF1_YEAST (P06782) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 633 Score = 70.9 bits (172), Expect = 2e-12 Identities = 42/126 (33%), Positives = 67/126 (53%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y + K LG G FG L +TG++ A K I+K+ L + I REI ++ L P Sbjct: 55 YQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLR-HP 113 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 +I++ + K + +V+E AG ELFD I+ + SE+ A + +++ V CH Sbjct: 114 HIIKLYDVIKSKDEIIMVIEY-AGNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRHK 172 Query: 552 VMHRDL 569 ++HRDL Sbjct: 173 IVHRDL 178
>KAPCG_HUMAN (P22612) cAMP-dependent protein kinase, gamma-catalytic subunit (EC| 2.7.11.11) (PKA C-gamma) Length = 350 Score = 70.9 bits (172), Expect = 2e-12 Identities = 46/140 (32%), Positives = 71/140 (50%) Frame = +3 Query: 150 DTILGKQYEDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDI 329 +T Q+E +R+ LG G FG L TG YA K ++K+K+V E I Sbjct: 36 NTASSDQFERLRT-------LGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHI 88 Query: 330 RREIQIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATIC 509 E +I+Q + P +V+ +++D +++VME GGE+F R+ G +SE A Sbjct: 89 LNEKRILQAIDF-PFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYA 147 Query: 510 RGVVNVVNVCHFMGVMHRDL 569 VV V H + ++HRDL Sbjct: 148 AQVVLAVQYLHSLDLIHRDL 167
>SAPKA_ORYSA (Q75H77) Serine/threonine-protein kinase SAPK10 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 10) Length = 362 Score = 70.9 bits (172), Expect = 2e-12 Identities = 45/127 (35%), Positives = 65/127 (51%), Gaps = 1/127 (0%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLS-GQ 368 Y L +++G G FGV L + G+ A K I + DK D + +I+ H S Sbjct: 23 YELVRDIGSGNFGVARLMRSRADGQLVAVKYIER------GDKIDENVQREIINHRSLRH 76 Query: 369 PNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFM 548 PNI+ F + +VME +GGELF+RI G +SE A + +++ V+ CH M Sbjct: 77 PNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLISGVSYCHSM 136 Query: 549 GVMHRDL 569 V HRDL Sbjct: 137 QVCHRDL 143
>KS6A4_MOUSE (Q9Z2B9) Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (RSK-like protein kinase) (RLSK) Length = 773 Score = 70.9 bits (172), Expect = 2e-12 Identities = 47/142 (33%), Positives = 76/142 (53%), Gaps = 2/142 (1%) Frame = +3 Query: 150 DTILGKQYE-DVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKED 326 D+ +QYE D+R LG+G F V C + +G+++A K +S+R +E+ Sbjct: 401 DSPFFQQYELDLRE-----PALGQGSFSVCRRCRQRQSGQEFAVKILSRRL------EEN 449 Query: 327 IRREIQIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATI 506 +RE+ ++ PN+V D+ ++V+EL GGEL + I K +SE A+ I Sbjct: 450 TQREVAALRLCQSHPNVVNLHEVLHDQLHTYLVLELLRGGELLEHIRKKRLFSESEASQI 509 Query: 507 CRGVVNVVNVCH-FMGVMHRDL 569 R +V+ V+ H GV+HRDL Sbjct: 510 LRSLVSAVSFMHEEAGVVHRDL 531 Score = 57.8 bits (138), Expect = 2e-08 Identities = 33/130 (25%), Positives = 66/130 (50%), Gaps = 4/130 (3%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEIS---TGRQYACKSISKRKLVSKAD-KEDIRREIQIMQHL 359 ++L K LG G +G +L + G+ YA K + K LV +A +E R E +++ + Sbjct: 33 FALLKVLGTGAYGKVFLVRKTGGHDAGKLYAMKVLRKAALVQRAKTQEHTRTERSVLELV 92 Query: 360 SGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVC 539 P +V A++ +H++++ +GGE+F + + ++ E +V + Sbjct: 93 RQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYGGEIVLALEHL 152 Query: 540 HFMGVMHRDL 569 H +G+++RDL Sbjct: 153 HKLGIIYRDL 162
>KS6A_CAEEL (Q21734) Putative ribosomal protein S6 kinase alpha (EC 2.7.11.1)| Length = 784 Score = 70.5 bits (171), Expect = 3e-12 Identities = 40/127 (31%), Positives = 64/127 (50%), Gaps = 1/127 (0%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y + +++G G V + C +T R+YA K + K D E+ I+ S Sbjct: 454 YEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVF-------DATEEVDILLRHSHHQ 506 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHY-SERAAATICRGVVNVVNVCHFM 548 +V+ YED+ +++++ ELC GGEL D+++ K SE+ A I ++N V H Sbjct: 507 FVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLNAVQYLHSQ 566 Query: 549 GVMHRDL 569 V HRDL Sbjct: 567 QVAHRDL 573 Score = 57.8 bits (138), Expect = 2e-08 Identities = 35/129 (27%), Positives = 69/129 (53%), Gaps = 3/129 (2%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEI---STGRQYACKSISKRKLVSKADKEDIRREIQIMQHLS 362 + L K LG+G FG +L ++ +G YA K + K L + D++ + E I+ H+S Sbjct: 104 FELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLKVR-DRQRTKLERNILAHIS 162 Query: 363 GQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCH 542 P IV+ A++ +G ++++++ GG+LF R+ + ++E + + H Sbjct: 163 -HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYLAELTLALEHLH 221 Query: 543 FMGVMHRDL 569 +G+++RDL Sbjct: 222 SLGIVYRDL 230
>MARK3_HUMAN (P27448) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| (Cdc25C-associated protein kinase 1) (cTAK1) (C-TAK1) (Serine/threonine protein kinase p78) (Ser/Thr protein kinase PAR-1) (Protein kinase STK10) Length = 776 Score = 70.5 bits (171), Expect = 3e-12 Identities = 46/149 (30%), Positives = 74/149 (49%), Gaps = 23/149 (15%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y L K +G+G F L I TGR+ A K I K +L + + + RE++IM+ L+ P Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQL-NPTSLQKLFREVRIMKILN-HP 113 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRG------------ 515 NIV+ E + +++++ME +GGE+FD ++A G E+ A + R Sbjct: 114 NIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQGCQAGQTIKVQV 173 Query: 516 -----------VVNVVNVCHFMGVMHRDL 569 +V+ V CH ++HRDL Sbjct: 174 SFDLLSLMFTFIVSAVQYCHQKRIVHRDL 202
>MKNK1_MOUSE (O08605) MAP kinase-interacting serine/threonine-protein kinase 1| (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (Mnk1) Length = 427 Score = 70.1 bits (170), Expect = 4e-12 Identities = 44/141 (31%), Positives = 72/141 (51%), Gaps = 1/141 (0%) Frame = +3 Query: 150 DTILGKQYEDVRSVYSLGKEL-GRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKED 326 D++ GK +EDV Y L EL G G + + +G++YA K I K+ S++ Sbjct: 38 DSLPGK-FEDV---YQLTSELLGEGAYAKVQGAVNLQSGKEYAVKIIEKQAGHSRSR--- 90 Query: 327 IRREIQIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATI 506 + RE++ + G NI+E +ED ++V E GG + I + H++ER A+ + Sbjct: 91 VFREVETLYQCQGNRNILELIEFFEDDTRFYLVFEKLQGGSILAHIQKRKHFNEREASRV 150 Query: 507 CRGVVNVVNVCHFMGVMHRDL 569 R V ++ H G+ HRDL Sbjct: 151 VRDVATALDFLHTKGIAHRDL 171
>AAPK1_PONPY (Q5RDH5) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 550 Score = 70.1 bits (170), Expect = 4e-12 Identities = 43/126 (34%), Positives = 67/126 (53%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y LG LG G FG + TG + A K ++++K+ S IRREIQ ++ L P Sbjct: 18 YILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLK-LFRHP 76 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 +I++ + +VME +GGELFD I G E+ + + + +++ V+ CH Sbjct: 77 HIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHM 136 Query: 552 VMHRDL 569 V+HRDL Sbjct: 137 VVHRDL 142
>AAPK1_HUMAN (Q13131) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 550 Score = 70.1 bits (170), Expect = 4e-12 Identities = 43/126 (34%), Positives = 67/126 (53%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y LG LG G FG + TG + A K ++++K+ S IRREIQ ++ L P Sbjct: 18 YILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLK-LFRHP 76 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 +I++ + +VME +GGELFD I G E+ + + + +++ V+ CH Sbjct: 77 HIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHM 136 Query: 552 VMHRDL 569 V+HRDL Sbjct: 137 VVHRDL 142
>AAPK1_RAT (P54645) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 548 Score = 70.1 bits (170), Expect = 4e-12 Identities = 43/126 (34%), Positives = 67/126 (53%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y LG LG G FG + TG + A K ++++K+ S IRREIQ ++ L P Sbjct: 16 YILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLK-LFRHP 74 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 +I++ + +VME +GGELFD I G E+ + + + +++ V+ CH Sbjct: 75 HIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHM 134 Query: 552 VMHRDL 569 V+HRDL Sbjct: 135 VVHRDL 140
>AAPK1_MOUSE (Q5EG47) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 548 Score = 70.1 bits (170), Expect = 4e-12 Identities = 43/126 (34%), Positives = 67/126 (53%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y LG LG G FG + TG + A K ++++K+ S IRREIQ ++ L P Sbjct: 16 YILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLK-LFRHP 74 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 +I++ + +VME +GGELFD I G E+ + + + +++ V+ CH Sbjct: 75 HIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHM 134 Query: 552 VMHRDL 569 V+HRDL Sbjct: 135 VVHRDL 140
>IPL1_YARLI (Q6C3J2) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 371 Score = 70.1 bits (170), Expect = 4e-12 Identities = 36/126 (28%), Positives = 68/126 (53%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 + +GK LG+G+FG YL + TG A K + K++LV ++ RRE++I +L Sbjct: 99 FEIGKALGKGKFGKVYLVKDKKTGFVSALKCMEKKELVEGNVEKQFRREVEIQSNLR-HT 157 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 N++ G + DK V++++E GEL+ + + ++E A++ + + H Sbjct: 158 NVLRLFGHFHDKDRVYLILEYVVHGELYKLLRNQKRFTESTASSYIYQMSEALLYLHGKN 217 Query: 552 VMHRDL 569 ++HRD+ Sbjct: 218 IIHRDI 223
>PHKG2_RAT (P31325) Phosphorylase b kinase gamma catalytic chain, testis/liver| isoform (EC 2.7.11.19) (PHK-gamma-T) (Phosphorylase kinase gamma subunit 2) Length = 406 Score = 70.1 bits (170), Expect = 4e-12 Identities = 41/126 (32%), Positives = 67/126 (53%), Gaps = 6/126 (4%) Frame = +3 Query: 210 LGRGQFGVTYLCTEISTGRQYACK--SISKRKLVSKADKEDIR----REIQIMQHLSGQP 371 +GRG V C +TG ++A K +S +L S E++R RE+ I++ ++G P Sbjct: 30 IGRGVSSVVRRCVHRATGDEFAVKIMEVSAERL-SLEQLEEVRDATRREMHILRQVAGHP 88 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 +I+ +YE + +V +L GELFD + K SE+ +I R ++ VN H Sbjct: 89 HIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVNFLHVNN 148 Query: 552 VMHRDL 569 ++HRDL Sbjct: 149 IVHRDL 154
>KCC4_YEAST (P25389) Probable serine/threonine-protein kinase KCC4 (EC| 2.7.11.1) Length = 1037 Score = 69.7 bits (169), Expect = 5e-12 Identities = 42/134 (31%), Positives = 68/134 (50%), Gaps = 8/134 (5%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKED--------IRREIQI 347 + LG+ LG G G L TG + A K ISK + + + I REI I Sbjct: 21 WKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVI 80 Query: 348 MQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNV 527 M+ LS PN++ +E ++++++E GELF+ ++ G ER A R ++ Sbjct: 81 MKLLS-HPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIG 139 Query: 528 VNVCHFMGVMHRDL 569 ++ CH +G++HRDL Sbjct: 140 ISYCHALGIVHRDL 153
>AURKC_HUMAN (Q9UQB9) Serine/threonine-protein kinase 13 (EC 2.7.11.1)| (Aurora/Ipl1/Eg2 protein 2) (Aurora/Ipl1-related kinase 3) (Aurora-C) Length = 309 Score = 69.3 bits (168), Expect = 7e-12 Identities = 37/126 (29%), Positives = 64/126 (50%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 + +G+ LG+G+FG YL + A K + K ++ + + +RREI+I HL P Sbjct: 43 FEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQ-HP 101 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NI+ + D V++++E GEL+ + E+ ATI + + + CH Sbjct: 102 NILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKK 161 Query: 552 VMHRDL 569 V+HRD+ Sbjct: 162 VIHRDI 167
>MYLK2_RABIT (P07313) Myosin light chain kinase 2, skeletal/cardiac muscle (EC| 2.7.11.18) (MLCK2) Length = 607 Score = 69.3 bits (168), Expect = 7e-12 Identities = 46/134 (34%), Positives = 72/134 (53%), Gaps = 3/134 (2%) Frame = +3 Query: 177 DVRSVYSLGKE--LGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIM 350 +V S +S+ + LG G+FG CTE STG + A K I K+ + DKE + EI++M Sbjct: 289 NVSSEFSMNSKEALGGGKFGAVCTCTEKSTGLKLAAKVIKKQ---TPKDKEMVMLEIEVM 345 Query: 351 QHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKG-HYSERAAATICRGVVNV 527 L+ + N+++ A E + + ME GGELF+RI+ + H +E R + + Sbjct: 346 NQLNHR-NLIQLYAAIETPHEIVLFMEYIEGGELFERIVDEDYHLTEVDTMVFVRQICDG 404 Query: 528 VNVCHFMGVMHRDL 569 + H M V+H DL Sbjct: 405 ILFMHKMRVLHLDL 418
>ASK2_ARATH (P43292) Serine/threonine-protein kinase ASK2 (EC 2.7.11.1)| Length = 353 Score = 69.3 bits (168), Expect = 7e-12 Identities = 44/126 (34%), Positives = 63/126 (50%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y + K+LG G FGV L T A K I + + + E++ REI + L P Sbjct: 4 YDVVKDLGAGNFGVARLLRHKDTKELVAMKYIERGRKID----ENVAREIINHRSLK-HP 58 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NI+ F + +VME +GGELFDRI G +SE A + ++ V+ CH + Sbjct: 59 NIIRFKEVILTPTHLAIVMEYASGGELFDRICTAGRFSEAEARYFFQQLICGVDYCHSLQ 118 Query: 552 VMHRDL 569 + HRDL Sbjct: 119 ICHRDL 124
>SAPK3_ORYSA (Q75V63) Serine/threonine-protein kinase SAPK3 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 3) (Protein kinase REK) Length = 334 Score = 68.9 bits (167), Expect = 9e-12 Identities = 45/127 (35%), Positives = 66/127 (51%), Gaps = 1/127 (0%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLS-GQ 368 Y KELG G FGV L + + A K I + K + E+++REI + H S Sbjct: 5 YEALKELGAGNFGVARLVRDKRSKELVAVKYIERGKKID----ENVQREI--INHRSLRH 58 Query: 369 PNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFM 548 PNI+ F + +VME AGGELF++I G +SE A + +++ V+ CH + Sbjct: 59 PNIIRFKEVCLTPTHLAIVMEYAAGGELFEQICTAGRFSEDEARYFFQQLISGVSYCHSL 118 Query: 549 GVMHRDL 569 + HRDL Sbjct: 119 EICHRDL 125
>HUNK_PANTR (Q68UT7) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) Length = 714 Score = 68.9 bits (167), Expect = 9e-12 Identities = 46/130 (35%), Positives = 67/130 (51%), Gaps = 4/130 (3%) Frame = +3 Query: 192 YSLG-KELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADK---EDIRREIQIMQHL 359 Y +G ++LG G F + TG + A K I K++ +K D +++RRE QI Q + Sbjct: 61 YLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKR--AKKDTYVTKNLRREGQIQQMI 118 Query: 360 SGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVC 539 PNI + E + S ++VMELC GG L +I K E A R +++ V Sbjct: 119 R-HPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEHL 177 Query: 540 HFMGVMHRDL 569 H GV+HRDL Sbjct: 178 HRAGVVHRDL 187
>HUNK_MOUSE (O88866) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) (Serine/threonine-protein kinase MAK-V) Length = 714 Score = 68.9 bits (167), Expect = 9e-12 Identities = 46/130 (35%), Positives = 67/130 (51%), Gaps = 4/130 (3%) Frame = +3 Query: 192 YSLG-KELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADK---EDIRREIQIMQHL 359 Y +G ++LG G F + TG + A K I K++ +K D +++RRE QI Q + Sbjct: 61 YLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKR--AKKDTYVTKNLRREGQIQQMI 118 Query: 360 SGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVC 539 PNI + E + S ++VMELC GG L +I K E A R +++ V Sbjct: 119 R-HPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLDEAEARRYIRQLISAVEHL 177 Query: 540 HFMGVMHRDL 569 H GV+HRDL Sbjct: 178 HRAGVVHRDL 187
>HUNK_HUMAN (P57058) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) (Serine/threonine-protein kinase MAK-V) (B19) Length = 714 Score = 68.9 bits (167), Expect = 9e-12 Identities = 46/130 (35%), Positives = 67/130 (51%), Gaps = 4/130 (3%) Frame = +3 Query: 192 YSLG-KELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADK---EDIRREIQIMQHL 359 Y +G ++LG G F + TG + A K I K++ +K D +++RRE QI Q + Sbjct: 61 YLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKR--AKKDTYVTKNLRREGQIQQMI 118 Query: 360 SGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVC 539 PNI + E + S ++VMELC GG L +I K E A R +++ V Sbjct: 119 R-HPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEHL 177 Query: 540 HFMGVMHRDL 569 H GV+HRDL Sbjct: 178 HRAGVVHRDL 187
>SNF1_CANTR (O94168) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 619 Score = 68.9 bits (167), Expect = 9e-12 Identities = 40/126 (31%), Positives = 65/126 (51%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y + K LG G FG L + TG++ A K I+++ L + + REI ++ L P Sbjct: 52 YQIIKTLGEGSFGKVKLAQHVGTGQKVALKIINRKTLAKSDMQGRVEREISYLRLLR-HP 110 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 +I++ + K + +V+E AG ELFD I+ +G E A + ++ V CH Sbjct: 111 HIIKLYDVIKSKDEIIMVIEF-AGKELFDYIVQRGKMPEDEARRFFQQIIAAVEYCHRHK 169 Query: 552 VMHRDL 569 ++HRDL Sbjct: 170 IVHRDL 175
>SNF1_CANAL (P52497) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 620 Score = 68.6 bits (166), Expect = 1e-11 Identities = 40/126 (31%), Positives = 65/126 (51%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y + K LG G FG L + TG++ A K I+++ L + + REI ++ L P Sbjct: 53 YQILKTLGEGSFGKVKLAQHLGTGQKVALKIINRKTLAKSDMQGRVEREISYLRLLR-HP 111 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 +I++ + K + +V+E AG ELFD I+ +G E A + ++ V CH Sbjct: 112 HIIKLYDVIKSKDEIIMVIEF-AGKELFDYIVQRGKMPEDEARRFFQQIIAAVEYCHRHK 170 Query: 552 VMHRDL 569 ++HRDL Sbjct: 171 IVHRDL 176
>SNRK_RAT (Q63553) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 746 Score = 68.6 bits (166), Expect = 1e-11 Identities = 43/131 (32%), Positives = 71/131 (54%), Gaps = 1/131 (0%) Frame = +3 Query: 180 VRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHL 359 + +Y L K LGRG F V L + TG + A K I K KL + A + +E++ M+ L Sbjct: 12 IAGLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLATGH-LFQEVRCMK-L 69 Query: 360 SGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIA-KGHYSERAAATICRGVVNVVNV 536 PNIV + + +++++EL GG++FD I+ + +E A +V+ ++ Sbjct: 70 VQHPNIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISY 129 Query: 537 CHFMGVMHRDL 569 CH + V+HRDL Sbjct: 130 CHKLHVVHRDL 140
>SNRK_MOUSE (Q8VDU5) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 748 Score = 68.6 bits (166), Expect = 1e-11 Identities = 43/131 (32%), Positives = 71/131 (54%), Gaps = 1/131 (0%) Frame = +3 Query: 180 VRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHL 359 + +Y L K LGRG F V L + TG + A K I K KL + A + +E++ M+ L Sbjct: 12 IAGLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLATGH-LFQEVRCMK-L 69 Query: 360 SGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIA-KGHYSERAAATICRGVVNVVNV 536 PNIV + + +++++EL GG++FD I+ + +E A +V+ ++ Sbjct: 70 VQHPNIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISY 129 Query: 537 CHFMGVMHRDL 569 CH + V+HRDL Sbjct: 130 CHKLHVVHRDL 140
>ST17B_MOUSE (Q8BG48) Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP| kinase-related apoptosis-inducing protein kinase 2) Length = 372 Score = 68.6 bits (166), Expect = 1e-11 Identities = 41/135 (30%), Positives = 73/135 (54%), Gaps = 3/135 (2%) Frame = +3 Query: 174 EDVRSVYSLG-KELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIM 350 E+ + Y+L KELGRG+F V C STG++YA KS+ KR+ + + +I EI ++ Sbjct: 26 ENFNNFYTLTPKELGRGKFAVVRQCISKSTGQEYAAKSLKKRRR-GQDCRAEILHEIAVL 84 Query: 351 QHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAK--GHYSERAAATICRGVVN 524 + P+++ YE+ + +V+E AGGE+F+ + + SE + + ++ Sbjct: 85 ELARSCPHVINLHEVYENATEIILVLEYAAGGEIFNLCLPELAEMVSENDVIRLIKQILE 144 Query: 525 VVNVCHFMGVMHRDL 569 V+ H ++H DL Sbjct: 145 GVHYLHQNNIVHLDL 159
>SNRK_HUMAN (Q9NRH2) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 765 Score = 68.6 bits (166), Expect = 1e-11 Identities = 43/131 (32%), Positives = 71/131 (54%), Gaps = 1/131 (0%) Frame = +3 Query: 180 VRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHL 359 + +Y L K LGRG F V L + TG + A K I K KL + A + +E++ M+ L Sbjct: 12 IAGLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLATGH-LFQEVRCMK-L 69 Query: 360 SGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIA-KGHYSERAAATICRGVVNVVNV 536 PNIV + + +++++EL GG++FD I+ + +E A +V+ ++ Sbjct: 70 VQHPNIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISY 129 Query: 537 CHFMGVMHRDL 569 CH + V+HRDL Sbjct: 130 CHKLHVVHRDL 140
>SAPK4_ORYSA (Q5N942) Serine/threonine-protein kinase SAPK4 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 4) Length = 360 Score = 68.6 bits (166), Expect = 1e-11 Identities = 45/127 (35%), Positives = 63/127 (49%), Gaps = 1/127 (0%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLS-GQ 368 Y +++G G FGV L T A K I + + E++ REI + H S Sbjct: 4 YEAVRDIGSGNFGVARLMRNRETRELVAVKCIERGHRID----ENVYREI--INHRSLRH 57 Query: 369 PNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFM 548 PNI+ F + +VME AGGELFDRI +G +SE A + ++ V+ CH M Sbjct: 58 PNIIRFKEVILTPTHLMIVMEFAAGGELFDRICDRGRFSEDEARYFFQQLICGVSYCHHM 117 Query: 549 GVMHRDL 569 + HRDL Sbjct: 118 QICHRDL 124
>KKK1_YEAST (P34244) Probable serine/threonine-protein kinase YKL101W (EC| 2.7.11.1) Length = 1518 Score = 68.6 bits (166), Expect = 1e-11 Identities = 47/170 (27%), Positives = 74/170 (43%), Gaps = 35/170 (20%) Frame = +3 Query: 165 KQYEDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLV------------- 305 ++ D + LGK LG+G G L + TG+ A K + K+K Sbjct: 72 RKSRDTVGPWKLGKTLGKGSSGRVRLAKNMETGQLAAIKIVPKKKAFVHCSNNGTVPNSY 131 Query: 306 ----------------------SKADKEDIRREIQIMQHLSGQPNIVEFCGAYEDKGSVH 419 S+ + I REI IM+ +S N++ +E+K ++ Sbjct: 132 SSSMVTSNVSSPSIASREHSNHSQTNPYGIEREIVIMKLIS-HTNVMALFEVWENKSELY 190 Query: 420 VVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMGVMHRDL 569 +V+E GGELFD +++KG ER A + +V V+ CH + HRDL Sbjct: 191 LVLEYVDGGELFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDL 240
>ST17A_HUMAN (Q9UEE5) Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP| kinase-related apoptosis-inducing protein kinase 1) Length = 414 Score = 68.6 bits (166), Expect = 1e-11 Identities = 41/136 (30%), Positives = 73/136 (53%), Gaps = 4/136 (2%) Frame = +3 Query: 174 EDVRSVYSL--GKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQI 347 E + YSL G+ELGRG+F V C + +G+++A K + KR+ + + +I EI + Sbjct: 53 EPFQDGYSLCPGRELGRGKFAVVRKCIKKDSGKEFAAKFMRKRR-KGQDCRMEIIHEIAV 111 Query: 348 MQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIA--KGHYSERAAATICRGVV 521 ++ P ++ YE + +V+E AGGE+FD+ +A + + E+ + R ++ Sbjct: 112 LELAQDNPWVINLHEVYETASEMILVLEYAAGGEIFDQCVADREEAFKEKDVQRLMRQIL 171 Query: 522 NVVNVCHFMGVMHRDL 569 V+ H V+H DL Sbjct: 172 EGVHFLHTRDVVHLDL 187
>PAK2_RAT (Q64303) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) (Gamma-PAK) (p62-PAK) Length = 524 Score = 68.2 bits (165), Expect = 2e-11 Identities = 42/131 (32%), Positives = 69/131 (52%) Frame = +3 Query: 177 DVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQH 356 D + Y+ +++G+G G + T+++ G++ A K I+ +K + KE I EI +M+ Sbjct: 244 DPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQK---QPKKELIINEILVMKE 300 Query: 357 LSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNV 536 L PNIV F +Y + VVME AGG L D ++ + E A +CR + + Sbjct: 301 LKN-PNIVNFLDSYLVGDELFVVMEYLAGGSLTD-VVTETCMDEAQIAAVCRECLQALEF 358 Query: 537 CHFMGVMHRDL 569 H V+HRD+ Sbjct: 359 LHANQVIHRDI 369
>PAK2_RABIT (Q29502) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) (Gamma-PAK) (p21-activated protein kinase I) (PAKI) Length = 524 Score = 68.2 bits (165), Expect = 2e-11 Identities = 42/131 (32%), Positives = 69/131 (52%) Frame = +3 Query: 177 DVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQH 356 D + Y+ +++G+G G + T+++ G++ A K I+ +K + KE I EI +M+ Sbjct: 244 DPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQK---QPKKELIINEILVMKE 300 Query: 357 LSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNV 536 L PNIV F +Y + VVME AGG L D ++ + E A +CR + + Sbjct: 301 LKN-PNIVNFLDSYLVGDELFVVMEYLAGGSLTD-VVTETCMDEAQIAAVCRECLQALEF 358 Query: 537 CHFMGVMHRDL 569 H V+HRD+ Sbjct: 359 LHANQVIHRDI 369
>PAK2_MOUSE (Q8CIN4) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) Length = 524 Score = 68.2 bits (165), Expect = 2e-11 Identities = 42/131 (32%), Positives = 69/131 (52%) Frame = +3 Query: 177 DVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQH 356 D + Y+ +++G+G G + T+++ G++ A K I+ +K + KE I EI +M+ Sbjct: 244 DPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQK---QPKKELIINEILVMKE 300 Query: 357 LSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNV 536 L PNIV F +Y + VVME AGG L D ++ + E A +CR + + Sbjct: 301 LKN-PNIVNFLDSYLVGDELFVVMEYLAGGSLTD-VVTETCMDEAQIAAVCRECLQALEF 358 Query: 537 CHFMGVMHRDL 569 H V+HRD+ Sbjct: 359 LHANQVIHRDI 369
>PAK2_HUMAN (Q13177) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) (PAK65) (Gamma-PAK) (S6/H4 kinase) Length = 524 Score = 68.2 bits (165), Expect = 2e-11 Identities = 42/131 (32%), Positives = 69/131 (52%) Frame = +3 Query: 177 DVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQH 356 D + Y+ +++G+G G + T+++ G++ A K I+ +K + KE I EI +M+ Sbjct: 244 DPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQK---QPKKELIINEILVMKE 300 Query: 357 LSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNV 536 L PNIV F +Y + VVME AGG L D ++ + E A +CR + + Sbjct: 301 LKN-PNIVNFLDSYLVGDELFVVMEYLAGGSLTD-VVTETCMDEAQIAAVCRECLQALEF 358 Query: 537 CHFMGVMHRDL 569 H V+HRD+ Sbjct: 359 LHANQVIHRDI 369
>NEK1_MOUSE (P51954) Serine/threonine-protein kinase Nek1 (EC 2.7.11.1)| (NimA-related protein kinase 1) Length = 1203 Score = 67.8 bits (164), Expect = 2e-11 Identities = 40/128 (31%), Positives = 71/128 (55%), Gaps = 6/128 (4%) Frame = +3 Query: 204 KELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQPNIVE 383 +++G G FG L GR Y K I+ ++ K ++++ RRE+ ++ ++ PNIV+ Sbjct: 8 QKIGEGSFGKAVLVKSTEDGRHYVIKEINISRMSDK-ERQESRREVAVLANMK-HPNIVQ 65 Query: 384 FCGAYEDKGSVHVVMELCAGGELFDRIIA-KGHYSERAA-----ATICRGVVNVVNVCHF 545 + ++E+ GS+++VM+ C GG+LF RI A KG + IC + +V H Sbjct: 66 YKESFEENGSLYIVMDYCEGGDLFKRINAQKGALFQEDQILDWFVQICLALKHV----HD 121 Query: 546 MGVMHRDL 569 ++HRD+ Sbjct: 122 RKILHRDI 129
>AAPK2_PONPY (Q5RD00) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 67.8 bits (164), Expect = 2e-11 Identities = 43/126 (34%), Positives = 65/126 (51%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y LG LG G FG + TG + A K ++++K+ S I+REIQ ++ L P Sbjct: 16 YVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLK-LFRHP 74 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 +I++ +VME +GGELFD I G E A + + +++ V+ CH Sbjct: 75 HIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHM 134 Query: 552 VMHRDL 569 V+HRDL Sbjct: 135 VVHRDL 140
>AAPK2_PIG (Q28948) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 67.8 bits (164), Expect = 2e-11 Identities = 43/126 (34%), Positives = 65/126 (51%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y LG LG G FG + TG + A K ++++K+ S I+REIQ ++ L P Sbjct: 16 YVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLK-LFRHP 74 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 +I++ +VME +GGELFD I G E A + + +++ V+ CH Sbjct: 75 HIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHM 134 Query: 552 VMHRDL 569 V+HRDL Sbjct: 135 VVHRDL 140
>AAPK2_HUMAN (P54646) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 67.8 bits (164), Expect = 2e-11 Identities = 43/126 (34%), Positives = 65/126 (51%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y LG LG G FG + TG + A K ++++K+ S I+REIQ ++ L P Sbjct: 16 YVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLK-LFRHP 74 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 +I++ +VME +GGELFD I G E A + + +++ V+ CH Sbjct: 75 HIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHM 134 Query: 552 VMHRDL 569 V+HRDL Sbjct: 135 VVHRDL 140
>ZYG1_CAEBR (Q621J7) Probable serine/threonine-protein kinase zyg-1 (EC| 2.7.11.1) (Zygote defective protein 1) Length = 709 Score = 67.8 bits (164), Expect = 2e-11 Identities = 45/136 (33%), Positives = 70/136 (51%) Frame = +3 Query: 162 GKQYEDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREI 341 GK + S +L +++G+G FGV Y + G + A K I + A + I+ EI Sbjct: 4 GKSGTKLSSFQNL-QQIGQGGFGVVY-SAQRENGEKVAIKKIG-----NAASQTRIKEEI 56 Query: 342 QIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVV 521 + M+ L + NIV+F + + G ++VMELC GG L D + KG + A I R ++ Sbjct: 57 KTMKLLRHR-NIVQFYETFFENGETYLVMELCEGGSLMDYVKQKGPLDDSTAVHILRQLI 115 Query: 522 NVVNVCHFMGVMHRDL 569 V H ++HRDL Sbjct: 116 AAVKYIHDENILHRDL 131
>PHKG2_MOUSE (Q9DB30) Phosphorylase b kinase gamma catalytic chain, testis/liver| isoform (EC 2.7.11.19) (PHK-gamma-T) (Phosphorylase kinase gamma subunit 2) Length = 406 Score = 67.8 bits (164), Expect = 2e-11 Identities = 40/126 (31%), Positives = 67/126 (53%), Gaps = 6/126 (4%) Frame = +3 Query: 210 LGRGQFGVTYLCTEISTGRQYACK--SISKRKLVSKADKEDIR----REIQIMQHLSGQP 371 +GRG V C +TG ++A K +S +L S E++R RE+ I++ ++G P Sbjct: 30 IGRGVSSVVRRCVHRATGDEFAVKIMEVSAERL-SLEQLEEVRDATRREMHILRQVAGHP 88 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 +I+ +YE + +V +L GELFD + K SE+ +I R ++ V+ H Sbjct: 89 HIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHANN 148 Query: 552 VMHRDL 569 ++HRDL Sbjct: 149 IVHRDL 154
>M3K2_MOUSE (Q61083) Mitogen-activated protein kinase kinase kinase 2 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2) Length = 619 Score = 67.8 bits (164), Expect = 2e-11 Identities = 41/130 (31%), Positives = 70/130 (53%), Gaps = 4/130 (3%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKE--DIRREIQIMQHLSG 365 + LGK LG+G FG YLC ++ TGR+ A K + + KE + EIQ++++L Sbjct: 356 WRLGKLLGQGAFGRVYLCYDVDTGRELAVKQVQFNPESPETSKEVNALECEIQLLKNLLH 415 Query: 366 QPNIVEFCGAYED--KGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVC 539 + IV++ G D + ++ + MEL GG + D++ A G +E R ++ V+ Sbjct: 416 E-RIVQYYGCLRDPQEKTLSIFMELSPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYL 474 Query: 540 HFMGVMHRDL 569 H ++HRD+ Sbjct: 475 HSNMIVHRDI 484
>MKNK1_XENLA (Q9YGW0) MAP kinase-interacting serine/threonine-protein kinase 1| (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (Mnk1) Length = 418 Score = 67.4 bits (163), Expect = 3e-11 Identities = 36/128 (28%), Positives = 63/128 (49%), Gaps = 1/128 (0%) Frame = +3 Query: 189 VYSLGKEL-GRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSG 365 +Y L EL G G + C + G+ YA K + K+ S++ + RE++ + G Sbjct: 35 LYRLTDELLGEGAYAKVQGCVSLQNGKDYAVKIVEKKAGHSRSR---VFREVETLYQCQG 91 Query: 366 QPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHF 545 NI+E ED ++V E GG + I + H++ER A+ + + + + ++ H Sbjct: 92 NKNILELIEFCEDDARFYLVFEKLLGGSILSHIQKRKHFNEREASKVVKDIASALDFLHT 151 Query: 546 MGVMHRDL 569 G+ HRDL Sbjct: 152 KGIAHRDL 159
>MKNK1_RAT (Q4G050) MAP kinase-interacting serine/threonine-protein kinase 1| (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (Mnk1) Length = 413 Score = 67.4 bits (163), Expect = 3e-11 Identities = 43/141 (30%), Positives = 71/141 (50%), Gaps = 1/141 (0%) Frame = +3 Query: 150 DTILGKQYEDVRSVYSLGKEL-GRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKED 326 D++ GK +EDV Y L EL G G + + +G++YA K I K+ S++ Sbjct: 26 DSLPGK-FEDV---YQLTSELLGEGAYAKVQGAVSLQSGKEYAVKIIEKQAGHSRSR--- 78 Query: 327 IRREIQIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATI 506 + RE++ + G NI+E +ED ++V E GG + I + H++E A+ + Sbjct: 79 VFREVETLYQCQGNRNILELIEFFEDDTRFYLVFEKLQGGSILAHIQKRKHFNELEASRV 138 Query: 507 CRGVVNVVNVCHFMGVMHRDL 569 R V ++ H G+ HRDL Sbjct: 139 VRDVATALDFLHTKGIAHRDL 159
>MKNK1_XENTR (Q66JF3) MAP kinase-interacting serine/threonine-protein kinase 1| (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (Mnk1) Length = 417 Score = 67.4 bits (163), Expect = 3e-11 Identities = 36/128 (28%), Positives = 63/128 (49%), Gaps = 1/128 (0%) Frame = +3 Query: 189 VYSLGKEL-GRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSG 365 +Y L EL G G + C + G+ YA K + K+ S++ + RE++ + G Sbjct: 35 LYRLTDELLGEGAYAKVQGCVSLQNGKDYAVKIVEKKAGHSRSR---VFREVETLYQCQG 91 Query: 366 QPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHF 545 NI+E ED ++V E GG + I + H++ER A+ + + + + ++ H Sbjct: 92 NKNILELIEFCEDDARFYLVFEKLRGGSILSHIQKRKHFNEREASKVVKDIASALDFLHT 151 Query: 546 MGVMHRDL 569 G+ HRDL Sbjct: 152 KGIAHRDL 159
>ASK1_ARATH (P43291) Serine/threonine-protein kinase ASK1 (EC 2.7.11.1)| Length = 363 Score = 67.4 bits (163), Expect = 3e-11 Identities = 44/127 (34%), Positives = 65/127 (51%), Gaps = 1/127 (0%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLS-GQ 368 Y L K++G G FGV L ++ A K I + + E++ REI + H S Sbjct: 4 YELVKDIGAGNFGVARLMKVKNSKELVAMKYIERGPKID----ENVAREI--INHRSLRH 57 Query: 369 PNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFM 548 PNI+ F + + ME AGGELF+RI + G +SE A + +++ V+ CH M Sbjct: 58 PNIIRFKEVVLTPTHLAIAMEYAAGGELFERICSAGRFSEDEARYFFQQLISGVSYCHAM 117 Query: 549 GVMHRDL 569 + HRDL Sbjct: 118 QICHRDL 124
>PHKG2_HUMAN (P15735) Phosphorylase b kinase gamma catalytic chain, testis/liver| isoform (EC 2.7.11.19) (PHK-gamma-T) (Phosphorylase kinase gamma subunit 2) (PSK-C3) Length = 406 Score = 67.4 bits (163), Expect = 3e-11 Identities = 38/125 (30%), Positives = 65/125 (52%), Gaps = 5/125 (4%) Frame = +3 Query: 210 LGRGQFGVTYLCTEISTGRQYACKSIS-KRKLVSKADKEDIR----REIQIMQHLSGQPN 374 +GRG V C +TG ++A K + + +S E++R RE I++ ++G P+ Sbjct: 30 IGRGVSSVVRRCVHRATGHEFAVKIMEVTAERLSPEQLEEVREATRRETHILRQVAGHPH 89 Query: 375 IVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMGV 554 I+ +YE + +V +L GELFD + K SE+ +I R ++ V+ H + Sbjct: 90 IITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHANNI 149 Query: 555 MHRDL 569 +HRDL Sbjct: 150 VHRDL 154
>MYLK2_RAT (P20689) Myosin light chain kinase 2, skeletal/cardiac muscle (EC| 2.7.11.18) (MLCK2) Length = 609 Score = 67.0 bits (162), Expect = 4e-11 Identities = 45/134 (33%), Positives = 72/134 (53%), Gaps = 3/134 (2%) Frame = +3 Query: 177 DVRSVYSLGKE--LGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIM 350 +V S +S+ + LG G+FG CTE STG + A K I K+ + DKE + EI++M Sbjct: 291 NVSSEFSMNSKEALGGGKFGAVCTCTERSTGLKLAAKVIKKQ---TPKDKEMVLLEIEVM 347 Query: 351 QHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGH-YSERAAATICRGVVNV 527 L+ + N+++ A E + + ME GGELF+RI+ + + +E R + + Sbjct: 348 NQLNHR-NLIQLYSAIETSHEIILFMEYIEGGELFERIVDEDYQLTEVDTMVFVRQICDG 406 Query: 528 VNVCHFMGVMHRDL 569 + H M V+H DL Sbjct: 407 ILFMHKMRVLHLDL 420
>AAPK2_RAT (Q09137) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 67.0 bits (162), Expect = 4e-11 Identities = 43/126 (34%), Positives = 65/126 (51%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y LG LG G FG + TG + A K ++++K+ S I+REIQ ++ L P Sbjct: 16 YVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLK-LFRHP 74 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 +I++ +VME +GGELFD I G E A + + +++ V+ CH Sbjct: 75 HIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEVEARRLFQQILSAVDYCHRHM 134 Query: 552 VMHRDL 569 V+HRDL Sbjct: 135 VVHRDL 140
>KIN4_YEAST (Q01919) Serine/threonine-protein kinase KIN4 (EC 2.7.11.1)| Length = 800 Score = 67.0 bits (162), Expect = 4e-11 Identities = 44/132 (33%), Positives = 70/132 (53%), Gaps = 6/132 (4%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYL-CTEISTG----RQYACKSISKRKLVSKADKE-DIRREIQIMQ 353 Y +G LG G+FG L T+ S+ +Q A K I + + ADKE I REI ++ Sbjct: 46 YIIGSTLGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKKDADKEIKIYREINALK 105 Query: 354 HLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVN 533 HL+ PNI+ ++ + +V+E +GGE + I K E +A + +++ VN Sbjct: 106 HLT-HPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKRRLKESSACRLFAQLISGVN 164 Query: 534 VCHFMGVMHRDL 569 H+ G++HRDL Sbjct: 165 YMHYKGLVHRDL 176
>GIN4_YEAST (Q12263) Serine/threonine-protein kinase GIN4 (EC 2.7.11.1)| Length = 1142 Score = 67.0 bits (162), Expect = 4e-11 Identities = 44/140 (31%), Positives = 69/140 (49%), Gaps = 14/140 (10%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKR----------KLVSKADKE----DI 329 + LG+ LG G G L STG++ A K ISK +V + I Sbjct: 19 WKLGETLGLGSTGKVQLARNGSTGQEAAVKVISKAVFNTGNVSGTSIVGSTTPDALPYGI 78 Query: 330 RREIQIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATIC 509 REI IM+ L+ PN++ +E +++V+E GELF+ ++ +G E A Sbjct: 79 EREIIIMKLLN-HPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAIRFF 137 Query: 510 RGVVNVVNVCHFMGVMHRDL 569 R ++ V+ CH +G++HRDL Sbjct: 138 RQIIIGVSYCHALGIVHRDL 157
>ST17A_RABIT (Q9GM70) Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP| kinase-related apoptosis-inducing protein kinase 1) (rDRAK1) Length = 397 Score = 66.6 bits (161), Expect = 5e-11 Identities = 40/136 (29%), Positives = 72/136 (52%), Gaps = 4/136 (2%) Frame = +3 Query: 174 EDVRSVYSL--GKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQI 347 E + YSL G+ELGRG+F V C + +G+++A K + KR+ + + +I EI + Sbjct: 36 EPFQDCYSLSPGRELGRGKFAVVRKCIQKDSGKEFAAKFMRKRR-KGQDCRMEIIHEIAV 94 Query: 348 MQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGH--YSERAAATICRGVV 521 ++ P ++ YE + +V+E AGGE+ D+ +A ++E+ + R ++ Sbjct: 95 LELAQDNPWVINLHEVYETSSEMILVLEYAAGGEISDQCVADRDEAFNEKDVQRLMRQIL 154 Query: 522 NVVNVCHFMGVMHRDL 569 V+ H V+H DL Sbjct: 155 EGVHFLHTHDVVHLDL 170
>PHKG1_RAT (P13286) Phosphorylase b kinase gamma catalytic chain, skeletal| muscle isoform (EC 2.7.11.19) (Phosphorylase kinase gamma subunit 1) Length = 387 Score = 66.6 bits (161), Expect = 5e-11 Identities = 41/126 (32%), Positives = 64/126 (50%), Gaps = 6/126 (4%) Frame = +3 Query: 210 LGRGQFGVTYLCTEISTGRQYACK--SISKRKLVSKADKEDIR----REIQIMQHLSGQP 371 LGRG V C T ++YA K I+ S + +++R +E+ I+Q +SG P Sbjct: 25 LGRGVSSVVRRCIHKPTCQEYAVKIIDITGGGSFSSEEVQELREATLKEVDILQKVSGHP 84 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NI++ YE +V +L GELFD + K +E+ I R ++ VV H + Sbjct: 85 NIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLTEKETRKIMRALLEVVCTLHKLN 144 Query: 552 VMHRDL 569 ++HRDL Sbjct: 145 IVHRDL 150
>KS6A5_MOUSE (Q8C050) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RLSK) Length = 863 Score = 66.6 bits (161), Expect = 5e-11 Identities = 37/130 (28%), Positives = 68/130 (52%), Gaps = 4/130 (3%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEIS---TGRQYACKSISKRKLVSKADK-EDIRREIQIMQHL 359 + L K LG G +G +L +IS G+ YA K + K +V KA E R E Q+++H+ Sbjct: 48 FELLKVLGTGAYGKVFLVRKISGHDAGKLYAMKVLKKATIVQKAKTTEHTRTERQVLEHI 107 Query: 360 SGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVC 539 P +V A++ + +H++++ GGELF + + ++E +V + Sbjct: 108 RQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHL 167 Query: 540 HFMGVMHRDL 569 H +G+++RD+ Sbjct: 168 HKLGIIYRDI 177 Score = 57.8 bits (138), Expect = 2e-08 Identities = 34/69 (49%), Positives = 44/69 (63%), Gaps = 2/69 (2%) Frame = +3 Query: 369 PNIVEFCGAYEDKGSVH--VVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCH 542 P IV F D G +H +VMEL GGELF+RI K H+SE A+ I R +V+ V+ H Sbjct: 542 PEIVLFI-LLSDNGQLHTFLVMELLNGGELFERIKRKKHFSETEASYIMRKLVSAVSHMH 600 Query: 543 FMGVMHRDL 569 +GV+HRDL Sbjct: 601 DVGVVHRDL 609 Score = 37.7 bits (86), Expect = 0.023 Identities = 21/68 (30%), Positives = 33/68 (48%) Frame = +3 Query: 204 KELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQPNIVE 383 K LG G F + C T + +A K ISKR + + ++EI ++ G PNIV+ Sbjct: 429 KPLGEGSFSICRKCVHKKTNQAFAVKIISKRM------EANTQKEITALKLCEGHPNIVK 482 Query: 384 FCGAYEDK 407 + D+ Sbjct: 483 LHEVFHDQ 490
>AAIP_WHEAT (Q02066) Abscisic acid-inducible protein kinase (EC 2.7.11.1)| (Fragment) Length = 332 Score = 66.6 bits (161), Expect = 5e-11 Identities = 43/120 (35%), Positives = 60/120 (50%), Gaps = 1/120 (0%) Frame = +3 Query: 213 GRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLS-GQPNIVEFC 389 G G FGV L ++ T +A K I + + E ++REI M H S PNI+ F Sbjct: 1 GSGNFGVAKLVRDVRTKEHFAVKFIERGHKID----EHVQREI--MNHRSLKHPNIIRFK 54 Query: 390 GAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMGVMHRDL 569 + +VME +GGELF RI G +SE + +++ V+ CH M V HRDL Sbjct: 55 EVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFFQQLISGVSYCHSMQVCHRDL 114
>AURKC_MOUSE (O88445) Serine/threonine-protein kinase 13 (EC 2.7.11.1)| (Aurora/Ipl1/Eg2 protein 1) (Aurora-C) Length = 282 Score = 66.6 bits (161), Expect = 5e-11 Identities = 35/126 (27%), Positives = 65/126 (51%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 + +G+ LGRG+FG YL A K + K ++ + + +RRE++I HL + Sbjct: 16 FEIGRPLGRGKFGRVYLARLKENHFIVALKVLFKSEIEKEGLEHQLRREVEIQAHLQHR- 74 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NI+ + D +++++E GGEL+ + ++ ATI + + + + CH Sbjct: 75 NILRLYNYFYDDTRIYLILEYAPGGELYKELQRHQKLDQQRTATIIQELSDALTYCHEKK 134 Query: 552 VMHRDL 569 V+HRD+ Sbjct: 135 VIHRDI 140
>KAPCG_MACMU (O62846) cAMP-dependent protein kinase, gamma-catalytic subunit (EC| 2.7.11.11) (PKA C-gamma) (Fragment) Length = 208 Score = 66.2 bits (160), Expect = 6e-11 Identities = 39/122 (31%), Positives = 62/122 (50%) Frame = +3 Query: 204 KELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQPNIVE 383 K LG G +G L TG YA K + K+K+V E E +I+Q ++ P +V+ Sbjct: 46 KTLGTGSYGRVMLVRHRETGNHYAMKILDKQKVVRLKQVEHTLNEKRILQAINF-PFLVK 104 Query: 384 FCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMGVMHR 563 +++D ++++VME GGE+F + G +SE A VV H + ++HR Sbjct: 105 LQFSFKDNSNLYLVMEYVPGGEMFSHLRRVGRFSEPQACFYAAQVVLAFQYLHSLDLIHR 164 Query: 564 DL 569 DL Sbjct: 165 DL 166
>PHKG1_HUMAN (Q16816) Phosphorylase b kinase gamma catalytic chain, skeletal| muscle isoform (EC 2.7.11.19) (Phosphorylase kinase gamma subunit 1) Length = 386 Score = 66.2 bits (160), Expect = 6e-11 Identities = 43/138 (31%), Positives = 68/138 (49%), Gaps = 6/138 (4%) Frame = +3 Query: 174 EDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKE--DIR----R 335 +D Y + LGRG V C T ++YA K I S + +E ++R + Sbjct: 13 QDFYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLK 72 Query: 336 EIQIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRG 515 E+ I++ +SG PNI++ YE +V +L GELFD + K SE+ I R Sbjct: 73 EVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRA 132 Query: 516 VVNVVNVCHFMGVMHRDL 569 ++ V+ H + ++HRDL Sbjct: 133 LLEVICTLHKLNIVHRDL 150
>PHKG1_MOUSE (P07934) Phosphorylase b kinase gamma catalytic chain, skeletal| muscle isoform (EC 2.7.11.19) (Phosphorylase kinase gamma subunit 1) Length = 387 Score = 66.2 bits (160), Expect = 6e-11 Identities = 40/126 (31%), Positives = 64/126 (50%), Gaps = 6/126 (4%) Frame = +3 Query: 210 LGRGQFGVTYLCTEISTGRQYACK--SISKRKLVSKADKEDIR----REIQIMQHLSGQP 371 LGRG V C T ++YA K I+ S + +++R +E+ I+Q +SG P Sbjct: 25 LGRGVSSVVRRCIHKPTCQEYAVKIIDITGGGSFSSEEVQELREATLKEVDILQKVSGHP 84 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NI++ YE +V +L GELFD + K +E+ I R ++ V+ H + Sbjct: 85 NIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLTEKETRKIMRALLEVICTLHKLN 144 Query: 552 VMHRDL 569 ++HRDL Sbjct: 145 IVHRDL 150
>CDC7_SCHPO (P41892) Cell division control protein 7 (EC 2.7.11.1)| Length = 1062 Score = 66.2 bits (160), Expect = 6e-11 Identities = 44/130 (33%), Positives = 67/130 (51%), Gaps = 2/130 (1%) Frame = +3 Query: 186 SVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSG 365 S +LG LG+G FG Y I G A K + K++ K+D I+ EI ++++L Sbjct: 7 SSITLGDCLGKGAFGAVYRGLNIKNGETVAVKKVKLSKML-KSDLSVIKMEIDLLKNLD- 64 Query: 366 QPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAK--GHYSERAAATICRGVVNVVNVC 539 PNIV++ G+Y+ S+ +++E C G L R I K G E A V+ + Sbjct: 65 HPNIVKYRGSYQTNDSLCIILEYCENGSL--RSICKNFGKIPENLVALYTFQVLQGLLYL 122 Query: 540 HFMGVMHRDL 569 H GV+HRD+ Sbjct: 123 HNQGVIHRDI 132
>PLK4_HUMAN (O00444) Serine/threonine-protein kinase PLK4 (EC 2.7.11.21)| (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine-protein kinase 18) Length = 970 Score = 65.9 bits (159), Expect = 8e-11 Identities = 41/141 (29%), Positives = 71/141 (50%), Gaps = 2/141 (1%) Frame = +3 Query: 153 TILGKQYEDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIR 332 T +G++ ED + +G LG+G F Y I TG + A K I K+ + + ++ Sbjct: 3 TCIGEKIED----FKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQ 58 Query: 333 REIQIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAK--GHYSERAAATI 506 E++I L P+I+E +ED V++V+E+C GE+ +R + +SE A Sbjct: 59 NEVKIHCQLK-HPSILELYNYFEDSNYVYLVLEMCHNGEM-NRYLKNRVKPFSENEARHF 116 Query: 507 CRGVVNVVNVCHFMGVMHRDL 569 ++ + H G++HRDL Sbjct: 117 MHQIITGMLYLHSHGILHRDL 137
>PLK4_MOUSE (Q64702) Serine/threonine-protein kinase PLK4 (EC 2.7.11.21)| (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine-protein kinase 18) Length = 925 Score = 65.9 bits (159), Expect = 8e-11 Identities = 40/139 (28%), Positives = 71/139 (51%), Gaps = 2/139 (1%) Frame = +3 Query: 159 LGKQYEDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRRE 338 +G++ ED + +G LG+G F Y I TG + A K I K+ + + ++ E Sbjct: 5 IGERIED----FKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNE 60 Query: 339 IQIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAK--GHYSERAAATICR 512 ++I L P+++E +ED V++V+E+C GE+ +R + +SER A Sbjct: 61 VKIHCQLK-HPSVLELYNYFEDNNYVYLVLEMCHNGEM-NRYLKNRMKPFSEREARHFMH 118 Query: 513 GVVNVVNVCHFMGVMHRDL 569 ++ + H G++HRDL Sbjct: 119 QIITGMLYLHSHGILHRDL 137
>KPK19_ARATH (Q39030) Serine/threonine-protein kinase AtPK19 (EC 2.7.11.1)| (Ribosomal-protein S6 kinase homolog) Length = 471 Score = 65.9 bits (159), Expect = 8e-11 Identities = 44/145 (30%), Positives = 73/145 (50%), Gaps = 5/145 (3%) Frame = +3 Query: 150 DTILGKQYEDVRSV-----YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKA 314 DT K E+V V + + K +G+G FG Y + T YA K + K K+V K Sbjct: 121 DTDSEKSPEEVSGVVGIEDFEVLKVVGQGAFGKVYQVRKKDTSEIYAMKVMRKDKIVEKN 180 Query: 315 DKEDIRREIQIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERA 494 E ++ E I+ + P IV+ +++ K +++V++ GG LF ++ +G + E Sbjct: 181 HAEYMKAERDILTKID-HPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDL 239 Query: 495 AATICRGVVNVVNVCHFMGVMHRDL 569 A +V+ V+ H G+MHRDL Sbjct: 240 ARVYTAEIVSAVSHLHEKGIMHRDL 264
>RAN1_SCHPO (P08092) Negative regulator of sexual conjugation and meiosis (EC| 2.7.11.1) Length = 470 Score = 65.9 bits (159), Expect = 8e-11 Identities = 38/122 (31%), Positives = 61/122 (50%), Gaps = 2/122 (1%) Frame = +3 Query: 210 LGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQPNIVEFC 389 +G G +GV Y +I G YA K++ K L K K R E+ + +S P I+ Sbjct: 24 IGAGAYGVVYKAEDIYDGTLYAVKALCKDGLNEKQKKLQAR-ELALHARVSSHPYIITLH 82 Query: 390 GAYEDKGSVHVVMELCAGGELFDRIIAKGHY--SERAAATICRGVVNVVNVCHFMGVMHR 563 E + +++VV++ C G+LF I K Y + T+ +++ V CH +G+ HR Sbjct: 83 RVLETEDAIYVVLQYCPNGDLFTYITEKKVYQGNSHLIKTVFLQLISAVEHCHSVGIYHR 142 Query: 564 DL 569 DL Sbjct: 143 DL 144
>SN1L2_MOUSE (Q8CFH6) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Salt-inducible kinase 2) Length = 931 Score = 65.9 bits (159), Expect = 8e-11 Identities = 42/126 (33%), Positives = 64/126 (50%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y + LG+G F V L +T + A K I K +L + E I RE+QIM+ L P Sbjct: 20 YDIEGTLGKGNFAVVKLGRHRTTKTEVAIKIIDKSQL-DAVNLEKIYREVQIMKMLD-HP 77 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 +I++ E K +++V E GE+FD + G +E A +++ V+ CH Sbjct: 78 HIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRK 137 Query: 552 VMHRDL 569 V+HRDL Sbjct: 138 VVHRDL 143
>KPSH2_HUMAN (Q96QS6) Serine/threonine-protein kinase H2 (EC 2.7.11.1) (PSK-H2)| Length = 385 Score = 65.9 bits (159), Expect = 8e-11 Identities = 38/126 (30%), Positives = 69/126 (54%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y + +G G F + +T + +A K + R+ + +E E+ +++ +S + Sbjct: 63 YDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETRE---REGREACVSELSVLRRVSHR- 118 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 IV+ +E + V++VMEL GGELFDR+IA+G ++ER A I + V + + H + Sbjct: 119 YIVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHALQ 178 Query: 552 VMHRDL 569 + HR+L Sbjct: 179 ITHRNL 184
>RKIN1_SECCE (Q02723) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 502 Score = 65.9 bits (159), Expect = 8e-11 Identities = 40/138 (28%), Positives = 66/138 (47%), Gaps = 2/138 (1%) Frame = +3 Query: 162 GKQYEDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREI 341 G ++ + Y LGK LG G F + T + A K +++R++ + +E +REI Sbjct: 4 GGEHSEALKNYYLGKILGVGTFAKVIIAEHKHTRHKVAIKVLNRRQMRAPEMEEKAKREI 63 Query: 342 QIMQHLSG--QPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRG 515 +I++ P+I+ + VVME C G+L D I+ K E A + Sbjct: 64 KILRLFIDLIHPHIIRVYEVIVTPKDIFVVMEYCQNGDLLDYILEKRRLQEDEARRTFQQ 123 Query: 516 VVNVVNVCHFMGVMHRDL 569 +++ V CH V+HRDL Sbjct: 124 IISAVEYCHRNKVVHRDL 141
>ICL1_KLULA (Q6CWQ4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 361 Score = 65.5 bits (158), Expect = 1e-10 Identities = 36/126 (28%), Positives = 66/126 (52%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 + +GK LG+G+FG Y TG A K++ K+++V ++ RRE++I Q Sbjct: 100 FEIGKILGKGKFGKVYCVKHRETGLICALKAMEKKEIVQYTIQKQFRREVEI-QGSFKHK 158 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 N+ + G + D+ V+++ME GEL+ + G +E A+ + N ++ H Sbjct: 159 NLTQLYGFFYDEKRVYLLMEYVYYGELYKFLKNNGPLNETLASYFVYQMANALDYMHSKN 218 Query: 552 VMHRDL 569 ++HRD+ Sbjct: 219 ILHRDI 224
>PHKG1_RABIT (P00518) Phosphorylase b kinase gamma catalytic chain, skeletal| muscle isoform (EC 2.7.11.19) (Phosphorylase kinase gamma subunit 1) Length = 386 Score = 65.5 bits (158), Expect = 1e-10 Identities = 39/126 (30%), Positives = 64/126 (50%), Gaps = 6/126 (4%) Frame = +3 Query: 210 LGRGQFGVTYLCTEISTGRQYACK--SISKRKLVSKADKEDIR----REIQIMQHLSGQP 371 LGRG V C T ++YA K ++ S + +++R +E+ I++ +SG P Sbjct: 25 LGRGVSSVVRRCIHKPTCKEYAVKIIDVTGGGSFSAEEVQELREATLKEVDILRKVSGHP 84 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NI++ YE +V +L GELFD + K SE+ I R ++ V+ H + Sbjct: 85 NIIQLKDTYETNTFFFLVFDLMKKGELFDYLTEKVTLSEKETRKIMRALLEVICALHKLN 144 Query: 552 VMHRDL 569 ++HRDL Sbjct: 145 IVHRDL 150
>ST17B_RAT (Q91XS8) Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP| kinase-related apoptosis-inducing protein kinase 2) Length = 371 Score = 65.5 bits (158), Expect = 1e-10 Identities = 40/135 (29%), Positives = 71/135 (52%), Gaps = 3/135 (2%) Frame = +3 Query: 174 EDVRSVYSLG-KELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIM 350 E+ + Y+L KELGRG+F V C STG++YA K + KR+ + + +I EI ++ Sbjct: 26 ENFNNFYTLTPKELGRGKFAVVRQCISKSTGQEYAAKFLKKRRR-GQDCRAEILHEIAVL 84 Query: 351 QHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAK--GHYSERAAATICRGVVN 524 + P+++ YE + +V+E AGGE+F+ + + SE + + ++ Sbjct: 85 ELARSCPHVINLHEVYETATEIILVLEYAAGGEIFNLCLPELAEMVSENDVIRLIKQILE 144 Query: 525 VVNVCHFMGVMHRDL 569 V+ H ++H DL Sbjct: 145 GVHYLHQNNIVHLDL 159
>SAPK8_ORYSA (Q7Y0B9) Serine/threonine-protein kinase SAPK8 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 8) Length = 371 Score = 65.5 bits (158), Expect = 1e-10 Identities = 42/126 (33%), Positives = 65/126 (51%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y L +++G G FGV L + T A K I + + + ++++REI + L P Sbjct: 33 YELVRDIGSGNFGVARLMRDRRTMELVAVKYIERGEKID----DNVQREIINHRSLK-HP 87 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 NI+ F + +VME +GGELF+RI +SE A + +++ V+ CH M Sbjct: 88 NIIRFKEVILTPTHLAIVMEYASGGELFERICKNVRFSEDEARYFFQQLISGVSYCHSMQ 147 Query: 552 VMHRDL 569 V HRDL Sbjct: 148 VCHRDL 153
>MYLK2_HUMAN (Q9H1R3) Myosin light chain kinase 2, skeletal/cardiac muscle (EC| 2.7.11.18) (MLCK2) Length = 595 Score = 65.5 bits (158), Expect = 1e-10 Identities = 44/134 (32%), Positives = 71/134 (52%), Gaps = 3/134 (2%) Frame = +3 Query: 177 DVRSVYSLGKE--LGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIM 350 +V S +S+ + LG G+FG C E +TG + A K I K+ + DKE + EI++M Sbjct: 277 NVSSEFSMNSKEALGGGKFGAVCTCMEKATGLKLAAKVIKKQ---TPKDKEMVLLEIEVM 333 Query: 351 QHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKG-HYSERAAATICRGVVNV 527 L+ + N+++ A E + + ME GGELF+RI+ + H +E R + + Sbjct: 334 NQLNHR-NLIQLYAAIETPHEIVLFMEYIEGGELFERIVDEDYHLTEVDTMVFVRQICDG 392 Query: 528 VNVCHFMGVMHRDL 569 + H M V+H DL Sbjct: 393 ILFMHKMRVLHLDL 406
>PKH3_ASHGO (Q753D9) Serine/threonine-protein kinase PKH3 (EC 2.7.11.1)| Length = 726 Score = 65.1 bits (157), Expect = 1e-10 Identities = 39/124 (31%), Positives = 63/124 (50%), Gaps = 2/124 (1%) Frame = +3 Query: 204 KELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHL--SGQPNI 377 +ELG G + Y E S+ QYA K SKR ++ + + + E + L + P I Sbjct: 14 EELGHGSYSTVYRVVERSSQHQYAIKICSKRHIIGENKVKYVTIEKNTLNLLGQANHPGI 73 Query: 378 VEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMGVM 557 ++ + D+ +++ VM+L GGEL + + +SE A +V+ V H MGV+ Sbjct: 74 IKLYYTFHDQENLYFVMDLAPGGELLQLLRRQRVFSEAWARHYMCQLVDTVEYIHSMGVI 133 Query: 558 HRDL 569 HRDL Sbjct: 134 HRDL 137
>KOK0_YEAST (Q12236) Probable serine/threonine-protein kinase YOL100W (EC| 2.7.11.1) Length = 1081 Score = 65.1 bits (157), Expect = 1e-10 Identities = 29/126 (23%), Positives = 61/126 (48%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 + G +G G + L T I T ++YA K ++K L+ + + + E +Q L+ P Sbjct: 179 FKFGSVIGDGAYSTVMLATSIDTKKRYAAKVLNKEYLIRQKKVKYVSIEKTALQKLNNSP 238 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 ++V ++D+ S++ ++E G+ + G E A +++ ++ H G Sbjct: 239 SVVRLFSTFQDESSLYFLLEYAPNGDFLSLMKKYGSLDETCARYYAAQIIDAIDYLHSNG 298 Query: 552 VMHRDL 569 ++HRD+ Sbjct: 299 IIHRDI 304
>LOK_DROME (O61267) Ovarian-specific serine/threonine-protein kinase Lok (EC| 2.7.11.1) (Protein loki) (dMNK) Length = 476 Score = 65.1 bits (157), Expect = 1e-10 Identities = 40/138 (28%), Positives = 70/138 (50%), Gaps = 6/138 (4%) Frame = +3 Query: 174 EDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKL------VSKADKEDIRR 335 E++ Y + ++LG G +G+ L + T +Q+A K + K L + +D + + Sbjct: 168 EEINKTYYVNRKLGSGAYGLVRLVYDTRTCQQFAMKIVKKNMLSGARPSTNFSDPDRVLN 227 Query: 336 EIQIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRG 515 E +IM++LS P +V + SV++V+E GG+L +RII+ SE + Sbjct: 228 EAKIMKNLS-HPCVVRMHDIVDKPDSVYMVLEFMRGGDLLNRIISNKLLSEDISKLYFYQ 286 Query: 516 VVNVVNVCHFMGVMHRDL 569 + + V H G+ HRDL Sbjct: 287 MCHAVKYLHDRGITHRDL 304
>M3K2_HUMAN (Q9Y2U5) Mitogen-activated protein kinase kinase kinase 2 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2) Length = 619 Score = 64.7 bits (156), Expect = 2e-10 Identities = 40/130 (30%), Positives = 69/130 (53%), Gaps = 4/130 (3%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKE--DIRREIQIMQHLSG 365 + LGK LG+G FG YLC ++ TGR+ A K + + KE + EIQ++++L Sbjct: 356 WRLGKLLGQGAFGRVYLCYDVDTGRELAVKQVQFDPDSPETSKEVNALECEIQLLKNLLH 415 Query: 366 QPNIVEFCGAYED--KGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVC 539 + IV++ G D + ++ + ME GG + D++ A G +E R ++ V+ Sbjct: 416 E-RIVQYYGCLRDPQEKTLSIFMEYMPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYL 474 Query: 540 HFMGVMHRDL 569 H ++HRD+ Sbjct: 475 HSNMIVHRDI 484
>MKNK1_BOVIN (Q58D94) MAP kinase-interacting serine/threonine-protein kinase 1| (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (Mnk1) Length = 420 Score = 64.7 bits (156), Expect = 2e-10 Identities = 43/141 (30%), Positives = 69/141 (48%), Gaps = 1/141 (0%) Frame = +3 Query: 150 DTILGKQYEDVRSVYSLGKEL-GRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKED 326 D++ GK +EDV Y L EL G G + + G +YA K I K S++ Sbjct: 26 DSLPGK-FEDV---YKLTSELLGEGANAKVQVAVSLQNGNEYAVKIIEKHAGHSRSR--- 78 Query: 327 IRREIQIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATI 506 + RE++ + G +I+E +ED ++V E GG + I + H++ER A+ + Sbjct: 79 VFREVETLYQCQGNKHILELIEFFEDDTRFYLVFEKLQGGSILAHIQKQKHFNEREASRV 138 Query: 507 CRGVVNVVNVCHFMGVMHRDL 569 R V ++ H G+ HRDL Sbjct: 139 VRDVAAALDFRHTKGIAHRDL 159
>ST17B_HUMAN (O94768) Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP| kinase-related apoptosis-inducing protein kinase 2) Length = 372 Score = 64.7 bits (156), Expect = 2e-10 Identities = 39/135 (28%), Positives = 68/135 (50%), Gaps = 3/135 (2%) Frame = +3 Query: 174 EDVRSVYSL-GKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIM 350 E+ + Y L KELGRG+F V C STG++YA K + KR+ + + +I EI ++ Sbjct: 26 ENFNNFYILTSKELGRGKFAVVRQCISKSTGQEYAAKFLKKRRR-GQDCRAEILHEIAVL 84 Query: 351 QHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAK--GHYSERAAATICRGVVN 524 + P ++ YE+ + +++E AGGE+F + + SE + + ++ Sbjct: 85 ELAKSCPRVINLHEVYENTSEIILILEYAAGGEIFSLCLPELAEMVSENDVIRLIKQILE 144 Query: 525 VVNVCHFMGVMHRDL 569 V H ++H DL Sbjct: 145 GVYYLHQNNIVHLDL 159
>PAK3_RAT (Q62829) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) (Beta-PAK) (p65-PAK) Length = 544 Score = 64.7 bits (156), Expect = 2e-10 Identities = 41/131 (31%), Positives = 69/131 (52%) Frame = +3 Query: 177 DVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQH 356 D + Y+ +++G+G G Y +I+TG++ A K ++ L + KE I EI +M+ Sbjct: 263 DPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMN---LQQQPKKELIINEILVMRE 319 Query: 357 LSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNV 536 + PNIV + +Y + VVME AGG L D ++ + E A +CR + ++ Sbjct: 320 -NKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTD-VVTETCMDEGQIAAVCRECLQALDF 377 Query: 537 CHFMGVMHRDL 569 H V+HRD+ Sbjct: 378 LHSNQVIHRDI 388
>PAK3_PONPY (Q7YQL3) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) Length = 559 Score = 64.7 bits (156), Expect = 2e-10 Identities = 41/131 (31%), Positives = 69/131 (52%) Frame = +3 Query: 177 DVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQH 356 D + Y+ +++G+G G Y +I+TG++ A K ++ L + KE I EI +M+ Sbjct: 278 DPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMN---LQQQPKKELIINEILVMRE 334 Query: 357 LSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNV 536 + PNIV + +Y + VVME AGG L D ++ + E A +CR + ++ Sbjct: 335 -NKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTD-VVTETCMDEGQIAAVCRECLQALDF 392 Query: 537 CHFMGVMHRDL 569 H V+HRD+ Sbjct: 393 LHSNQVIHRDI 403
>PAK3_PANTR (Q7YQL4) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) Length = 559 Score = 64.7 bits (156), Expect = 2e-10 Identities = 41/131 (31%), Positives = 69/131 (52%) Frame = +3 Query: 177 DVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQH 356 D + Y+ +++G+G G Y +I+TG++ A K ++ L + KE I EI +M+ Sbjct: 278 DPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMN---LQQQPKKELIINEILVMRE 334 Query: 357 LSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNV 536 + PNIV + +Y + VVME AGG L D ++ + E A +CR + ++ Sbjct: 335 -NKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTD-VVTETCMDEGQIAAVCRECLQALDF 392 Query: 537 CHFMGVMHRDL 569 H V+HRD+ Sbjct: 393 LHSNQVIHRDI 403
>PAK3_MOUSE (Q61036) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) (Beta-PAK) (CDC42/RAC effector kinase PAK-B) Length = 559 Score = 64.7 bits (156), Expect = 2e-10 Identities = 41/131 (31%), Positives = 69/131 (52%) Frame = +3 Query: 177 DVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQH 356 D + Y+ +++G+G G Y +I+TG++ A K ++ L + KE I EI +M+ Sbjct: 278 DPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMN---LQQQPKKELIINEILVMRE 334 Query: 357 LSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNV 536 + PNIV + +Y + VVME AGG L D ++ + E A +CR + ++ Sbjct: 335 -NKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTD-VVTETCMDEGQIAAVCRECLQALDF 392 Query: 537 CHFMGVMHRDL 569 H V+HRD+ Sbjct: 393 LHSNQVIHRDI 403
>PAK3_HUMAN (O75914) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) (Beta-PAK) (Oligophrenin-3) Length = 559 Score = 64.7 bits (156), Expect = 2e-10 Identities = 41/131 (31%), Positives = 69/131 (52%) Frame = +3 Query: 177 DVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQH 356 D + Y+ +++G+G G Y +I+TG++ A K ++ L + KE I EI +M+ Sbjct: 278 DPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMN---LQQQPKKELIINEILVMRE 334 Query: 357 LSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNV 536 + PNIV + +Y + VVME AGG L D ++ + E A +CR + ++ Sbjct: 335 -NKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTD-VVTETCMDEGQIAAVCRECLQALDF 392 Query: 537 CHFMGVMHRDL 569 H V+HRD+ Sbjct: 393 LHSNQVIHRDI 403
>PAKM_DROME (Q9VXE5) Serine/threonine-protein kinase PAK mbt (EC 2.7.11.1)| (p21-activated kinase-related protein) (Protein mushroom bodies tiny) Length = 639 Score = 64.3 bits (155), Expect = 2e-10 Identities = 41/121 (33%), Positives = 61/121 (50%) Frame = +3 Query: 207 ELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQPNIVEF 386 ++G G G + T+ STGRQ A K + RK + +E + E+ IM+ PNIVE Sbjct: 373 KIGEGSTGTVCIATDKSTGRQVAVKKMDLRK---QQRRELLFNEVVIMRDYH-HPNIVET 428 Query: 387 CGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMGVMHRD 566 ++ + VVME GG L D I+ E AT+C+ + + H GV+HRD Sbjct: 429 YSSFLVNDELWVVMEYLEGGALTD-IVTHSRMDEEQIATVCKQCLKALAYLHSQGVIHRD 487 Query: 567 L 569 + Sbjct: 488 I 488
>CHK2_MOUSE (Q9Z265) Serine/threonine-protein kinase Chk2 (EC 2.7.11.1)| Length = 546 Score = 64.3 bits (155), Expect = 2e-10 Identities = 41/137 (29%), Positives = 68/137 (49%), Gaps = 5/137 (3%) Frame = +3 Query: 174 EDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKE-----DIRRE 338 +++R Y + K LG G G + E T ++ A K ISKR+ + +E + E Sbjct: 218 KELRDEYIMSKTLGSGACGEVKMAFERKTCQKVAIKIISKRRFALGSSREADTAPSVETE 277 Query: 339 IQIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGV 518 I+I++ L+ P I++ + D ++V+EL GGELFDR++ E + Sbjct: 278 IEILKKLN-HPCIIKIKDVF-DAEDYYIVLELMEGGELFDRVVGNKRLKEATCKLYFYQM 335 Query: 519 VNVVNVCHFMGVMHRDL 569 + V H G++HRDL Sbjct: 336 LVAVQYLHENGIIHRDL 352
>SN1L2_PONPY (Q5REX1) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) Length = 925 Score = 64.3 bits (155), Expect = 2e-10 Identities = 41/126 (32%), Positives = 63/126 (50%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y + LG+G F V L T + A K I K +L + E I RE+QIM+ L P Sbjct: 20 YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQL-DAVNLEKIYREVQIMKMLD-HP 77 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 +I++ E K +++V E GE+FD + G +E A +++ V+ CH Sbjct: 78 HIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRK 137 Query: 552 VMHRDL 569 ++HRDL Sbjct: 138 IVHRDL 143
>SAPK5_ORYSA (Q7XKA8) Serine/threonine-protein kinase SAPK5 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 5) Length = 370 Score = 64.3 bits (155), Expect = 2e-10 Identities = 47/135 (34%), Positives = 64/135 (47%) Frame = +3 Query: 165 KQYEDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQ 344 ++YE VR E+G G FGV L T A K I + + E++ REI Sbjct: 2 EKYEPVR-------EIGAGNFGVAKLMRNKETRELVAMKFIERGNRID----ENVFREIV 50 Query: 345 IMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVN 524 + L PNI+ F + +VME AGGELF+RI G + E A + +V Sbjct: 51 NHRSLR-HPNIIRFKEVVVTGRHLAIVMEYAAGGELFERICEAGRFHEDEARYFFQQLVC 109 Query: 525 VVNVCHFMGVMHRDL 569 V+ CH M + HRDL Sbjct: 110 GVSYCHAMQICHRDL 124
>RIM15_YEAST (P43565) Serine/threonine-protein kinase RIM15 (EC 2.7.11.1)| Length = 1770 Score = 64.3 bits (155), Expect = 2e-10 Identities = 35/126 (27%), Positives = 64/126 (50%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y + K + +G +G YL + TG +A K + K +++K +++ E IM S +P Sbjct: 794 YDILKPISKGAYGSVYLARKKLTGDYFAIKVLRKSDMIAKNQVTNVKSERAIMMVQSDKP 853 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 + ++++K ++ +VME GG+L I G+ ++ A +V VN H G Sbjct: 854 YVARLFASFQNKDNLFLVMEYLPGGDLATLIKMMGYLPDQWAKQYLTEIVVGVNDMHQNG 913 Query: 552 VMHRDL 569 ++H DL Sbjct: 914 IIHHDL 919
>KAPCA_BOVIN (P00517) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 64.3 bits (155), Expect = 2e-10 Identities = 38/122 (31%), Positives = 63/122 (51%) Frame = +3 Query: 204 KELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQPNIVE 383 K LG G FG L + TG YA K + K+K+V E E +I+Q ++ P +V+ Sbjct: 47 KTLGTGSFGRVMLVKHMETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNF-PFLVK 105 Query: 384 FCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMGVMHR 563 +++D ++++VME GGE+F + G +SE A +V H + +++R Sbjct: 106 LEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYR 165 Query: 564 DL 569 DL Sbjct: 166 DL 167
>TSSK3_MOUSE (Q9D2E1) Testis-specific serine/threonine-protein kinase 3 (EC| 2.7.11.1) (TSSK-3) (Testis-specific kinase 3) (TSK-3) (Serine/threonine-protein kinase 22C) Length = 268 Score = 64.3 bits (155), Expect = 2e-10 Identities = 41/127 (32%), Positives = 63/127 (49%), Gaps = 1/127 (0%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y LGK +G G + R+ A K I K + + + RE+QI++ L + Sbjct: 10 YQLGKTIGEGTYSKVKEAFSKKHQRKVAIKIIDKMGGPEEFIQRFLPRELQIVRTLDHK- 68 Query: 372 NIVEFCGAYEDK-GSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFM 548 NI++ E G +++VMEL GG++FD ++ G E A + R +V + CH Sbjct: 69 NIIQVYEMLESADGKIYLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGC 128 Query: 549 GVMHRDL 569 GV HRDL Sbjct: 129 GVAHRDL 135
>SN1L2_HUMAN (Q9H0K1) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Qin-induced kinase) Length = 926 Score = 64.3 bits (155), Expect = 2e-10 Identities = 41/126 (32%), Positives = 63/126 (50%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y + LG+G F V L T + A K I K +L + E I RE+QIM+ L P Sbjct: 20 YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQL-DAVNLEKIYREVQIMKMLD-HP 77 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 +I++ E K +++V E GE+FD + G +E A +++ V+ CH Sbjct: 78 HIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRK 137 Query: 552 VMHRDL 569 ++HRDL Sbjct: 138 IVHRDL 143
>CDPK1_PLAYO (Q7RAH3) Calcium-dependent protein kinase 1 (EC 2.7.11.1)| Length = 534 Score = 63.9 bits (154), Expect = 3e-10 Identities = 46/151 (30%), Positives = 74/151 (49%), Gaps = 14/151 (9%) Frame = +3 Query: 159 LGKQYEDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADK------ 320 +G+ Y VR +LG G +G LC E + + A K I K S+ DK Sbjct: 52 IGESYFKVR-------KLGSGAYGEVLLCKEKNGHSEKAIKVIKK----SQFDKGRYNDD 100 Query: 321 --------EDIRREIQIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKG 476 E+I EI +++ L PNI++ +EDK ++V E GGELF++II + Sbjct: 101 NKNIEKFHEEIYNEISLLKSLD-HPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQIINRH 159 Query: 477 HYSERAAATICRGVVNVVNVCHFMGVMHRDL 569 + E AA I + +++ + H ++HRD+ Sbjct: 160 KFDECDAANIMKQILSGICYLHKHNIVHRDI 190
>PAK1_RAT (P35465) Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1)| (p21-activated kinase 1) (PAK-1) (P68-PAK) (Alpha-PAK) (Protein kinase MUK2) Length = 544 Score = 63.9 bits (154), Expect = 3e-10 Identities = 40/131 (30%), Positives = 68/131 (51%) Frame = +3 Query: 177 DVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQH 356 D + Y+ +++G+G G Y +++TG++ A K ++ L + KE I EI +M+ Sbjct: 264 DPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMN---LQQQPKKELIINEILVMRE 320 Query: 357 LSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNV 536 + PNIV + +Y + VVME AGG L D ++ + E A +CR + + Sbjct: 321 -NKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTD-VVTETCMDEGQIAAVCRECLQALEF 378 Query: 537 CHFMGVMHRDL 569 H V+HRD+ Sbjct: 379 LHSNQVIHRDI 389
>CAKI_DROME (Q24210) Calcium/calmodulin-dependent protein kinase (EC 2.7.11.17)| (CAKI) (Peripheral plasma membrane protein CaMGUK) Length = 898 Score = 63.9 bits (154), Expect = 3e-10 Identities = 38/133 (28%), Positives = 63/133 (47%), Gaps = 6/133 (4%) Frame = +3 Query: 189 VYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKA--DKEDIRREIQIMQHLS 362 VY L + +G+G F + C + +Q+A K + K + D++RE I H+ Sbjct: 11 VYELCEVIGKGPFSIVRRCIHRESNQQFAVKIVDVAKFTASPGLSTADLKREATIC-HML 69 Query: 363 GQPNIVEFCGAYEDKGSVHVVMELCAGGEL----FDRIIAKGHYSERAAATICRGVVNVV 530 P+IVE Y +G +++V E G +L R +A YSE A R ++ + Sbjct: 70 KHPHIVELLETYSSEGMLYMVFEFMEGSDLCFEVVRRAVAGFVYSEAVACHYMRQILEAL 129 Query: 531 NVCHFMGVMHRDL 569 CH ++HRD+ Sbjct: 130 RYCHENDILHRDV 142
>PAK1_MOUSE (O88643) Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1)| (p21-activated kinase 1) (PAK-1) (P65-PAK) (Alpha-PAK) (CDC42/RAC effector kinase PAK-A) Length = 545 Score = 63.9 bits (154), Expect = 3e-10 Identities = 43/141 (30%), Positives = 72/141 (51%), Gaps = 9/141 (6%) Frame = +3 Query: 174 EDVRSVYSLG---------KELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKED 326 E +RS+ S+G +++G+G G Y +++TG++ A K ++ L + KE Sbjct: 255 EKLRSIVSVGDPKKKYTPFEKIGQGASGTVYTAMDVATGQEVAIKQMN---LQQQPKKEL 311 Query: 327 IRREIQIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATI 506 I EI +M+ + PNIV + +Y + VVME AGG L D ++ + E A + Sbjct: 312 IINEILVMRE-NKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTD-VVTETCMDEGQIAAV 369 Query: 507 CRGVVNVVNVCHFMGVMHRDL 569 CR + + H V+HRD+ Sbjct: 370 CRECLQALEFLHSNQVIHRDI 390
>PAK1_HUMAN (Q13153) Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1)| (p21-activated kinase 1) (PAK-1) (P65-PAK) (Alpha-PAK) Length = 545 Score = 63.9 bits (154), Expect = 3e-10 Identities = 40/131 (30%), Positives = 68/131 (51%) Frame = +3 Query: 177 DVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQH 356 D + Y+ +++G+G G Y +++TG++ A K ++ L + KE I EI +M+ Sbjct: 265 DPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMN---LQQQPKKELIINEILVMRE 321 Query: 357 LSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNV 536 + PNIV + +Y + VVME AGG L D ++ + E A +CR + + Sbjct: 322 -NKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTD-VVTETCMDEGQIAAVCRECLQALEF 379 Query: 537 CHFMGVMHRDL 569 H V+HRD+ Sbjct: 380 LHSNQVIHRDI 390
>CHK2_HUMAN (O96017) Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (Cds1)| Length = 543 Score = 63.5 bits (153), Expect = 4e-10 Identities = 42/135 (31%), Positives = 67/135 (49%), Gaps = 5/135 (3%) Frame = +3 Query: 180 VRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKE-----DIRREIQ 344 +R Y + K LG G G L E T ++ A K ISKRK + +E ++ EI+ Sbjct: 216 LRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIE 275 Query: 345 IMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVN 524 I++ L+ P I++ + D ++V+EL GGELFD+++ E ++ Sbjct: 276 ILKKLN-HPCIIKIKNFF-DAEDYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLL 333 Query: 525 VVNVCHFMGVMHRDL 569 V H G++HRDL Sbjct: 334 AVQYLHENGIIHRDL 348
>PDPK1_HUMAN (O15530) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (hPDK1) Length = 556 Score = 63.5 bits (153), Expect = 4e-10 Identities = 35/126 (27%), Positives = 57/126 (45%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 + GK LG G F L E++T R+YA K + KR ++ + + RE +M L P Sbjct: 82 FKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLD-HP 140 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 V+ ++D ++ + GEL I G + E +V+ + H G Sbjct: 141 FFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKG 200 Query: 552 VMHRDL 569 ++HRDL Sbjct: 201 IIHRDL 206
>PLK2_HUMAN (Q9NYY3) Serine/threonine-protein kinase PLK2 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-2) (Serine/threonine-protein kinase SNK) (Serum-inducible kinase) Length = 685 Score = 63.5 bits (153), Expect = 4e-10 Identities = 46/190 (24%), Positives = 84/190 (44%), Gaps = 1/190 (0%) Frame = +3 Query: 3 GYSHQPKQAQTPPSYNNAQPPP-QAEVRYTXXXXXXXXXXXXXXXXXXXXDTILGKQYED 179 G K+ + P +QPP QA+V D GK+Y Sbjct: 25 GCGADSKKKRPPQPPEESQPPQSQAQVPPAAPHHHHHHSHSGPEISRIIVDPTTGKRY-- 82 Query: 180 VRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHL 359 GK LG+G F Y T+++ + YA K I ++ +E I +EI++ + L Sbjct: 83 -----CRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRIL 137 Query: 360 SGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVC 539 + ++V+F +EDK ++++++E C+ + + A+ +E R +V+ + Sbjct: 138 HHK-HVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYLRQIVSGLKYL 196 Query: 540 HFMGVMHRDL 569 H ++HRDL Sbjct: 197 HEQEILHRDL 206
>PKH1_YEAST (Q03407) Serine/threonine-protein kinase PKH1 (EC 2.7.11.1)| (3-phosphoinositide-dependent protein kinase 1) Length = 766 Score = 63.5 bits (153), Expect = 4e-10 Identities = 32/126 (25%), Positives = 64/126 (50%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 + G++LG G + L T +G++YA K +SK L+ + + + E +Q L+G Sbjct: 125 FKFGEQLGDGSYSSVVLATARDSGKKYAVKVLSKEYLIRQKKVKYVTVEKLALQKLNGTK 184 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 I + ++D+ S++ ++E G+ I G +E A +++ V+ H +G Sbjct: 185 GIFKLFFTFQDEASLYFLLEYAPHGDFLGLIKKYGSLNETCARYYASQIIDAVDSLHNIG 244 Query: 552 VMHRDL 569 ++HRD+ Sbjct: 245 IIHRDI 250
>KAPCA_SHEEP (Q9MZD9) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 63.5 bits (153), Expect = 4e-10 Identities = 38/122 (31%), Positives = 62/122 (50%) Frame = +3 Query: 204 KELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQPNIVE 383 K LG G FG L TG YA K + K+K+V E E +I+Q ++ P +V+ Sbjct: 47 KTLGTGSFGRVMLVKHTETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNF-PFLVK 105 Query: 384 FCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMGVMHR 563 +++D ++++VME GGE+F + G +SE A +V H + +++R Sbjct: 106 LEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYR 165 Query: 564 DL 569 DL Sbjct: 166 DL 167
>PDPK1_RAT (O55173) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (Protein kinase B kinase) (PkB kinase) Length = 559 Score = 63.5 bits (153), Expect = 4e-10 Identities = 35/126 (27%), Positives = 57/126 (45%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 + GK LG G F L E++T R+YA K + KR ++ + + RE +M L P Sbjct: 85 FKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLD-HP 143 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 V+ ++D ++ + GEL I G + E +V+ + H G Sbjct: 144 FFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKG 203 Query: 552 VMHRDL 569 ++HRDL Sbjct: 204 IIHRDL 209
>PDPK1_MOUSE (Q9Z2A0) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (mPDK1) Length = 559 Score = 63.5 bits (153), Expect = 4e-10 Identities = 35/126 (27%), Positives = 57/126 (45%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 + GK LG G F L E++T R+YA K + KR ++ + + RE +M L P Sbjct: 85 FKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLD-HP 143 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 V+ ++D ++ + GEL I G + E +V+ + H G Sbjct: 144 FFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKG 203 Query: 552 VMHRDL 569 ++HRDL Sbjct: 204 IIHRDL 209
>PLK2_CAEEL (Q9N2L7) Serine/threonine-protein kinase plk-2 (EC 2.7.11.21)| (Polo-like kinase 2) Length = 632 Score = 63.2 bits (152), Expect = 5e-10 Identities = 38/126 (30%), Positives = 65/126 (51%) Frame = +3 Query: 192 YSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQP 371 Y GK LG+G F Y STG +A K + K L+ + ++ + +E+QI ++L + Sbjct: 36 YEKGKFLGKGGFAHCYELRNKSTGELFAGKVVPKALLIKQYQRDKMAQEVQIHRNLQHR- 94 Query: 372 NIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVNVVNVCHFMG 551 N+V+ +EDK +V++ +ELC L + + +E A +V V H + Sbjct: 95 NVVKLYHFFEDKSNVYITLELCPRRSLMELHKRRKAVTEPEARYFTYQIVEGVLYLHNLK 154 Query: 552 VMHRDL 569 ++HRDL Sbjct: 155 IVHRDL 160
>MKNK2_HUMAN (Q9HBH9) MAP kinase-interacting serine/threonine-protein kinase 2| (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (Mnk2) Length = 465 Score = 63.2 bits (152), Expect = 5e-10 Identities = 36/135 (26%), Positives = 68/135 (50%), Gaps = 1/135 (0%) Frame = +3 Query: 168 QYEDVRSVYSLGKE-LGRGQFGVTYLCTEISTGRQYACKSISKRKLVSKADKEDIRREIQ 344 ++EDV Y L ++ LG G C + T ++YA K I K+ + + RE++ Sbjct: 78 RFEDV---YQLQEDVLGEGAHARVQTCINLITSQEYAVKIIEKQP---GHIRSRVFREVE 131 Query: 345 IMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHYSERAAATICRGVVN 524 ++ G N++E +E++ ++V E GG + I + H++E A+ + + V + Sbjct: 132 MLYQCQGHRNVLELIEFFEEEDRFYLVFEKMRGGSILSHIHKRRHFNELEASVVVQDVAS 191 Query: 525 VVNVCHFMGVMHRDL 569 ++ H G+ HRDL Sbjct: 192 ALDFLHNKGIAHRDL 206
>CDPK1_PLAFK (P62343) Calcium-dependent protein kinase 1 (EC 2.7.11.1) (PfCPK)| (PfCDPK1) Length = 523 Score = 63.2 bits (152), Expect = 5e-10 Identities = 45/149 (30%), Positives = 73/149 (48%), Gaps = 12/149 (8%) Frame = +3 Query: 159 LGKQYEDVRSVYSLGKELGRGQFGVTYLCTEISTGRQYACKSISKRKL----------VS 308 +G+ Y VR +LG G +G LC E + A K I K + + Sbjct: 51 IGESYFKVR-------KLGSGAYGEVLLCREKHGHGEKAIKVIKKSQFDKMKYSITNKIE 103 Query: 309 KADK--EDIRREIQIMQHLSGQPNIVEFCGAYEDKGSVHVVMELCAGGELFDRIIAKGHY 482 DK E+I EI +++ L PNI++ +EDK ++V E GGELF++II + + Sbjct: 104 CDDKIHEEIYNEISLLKSLD-HPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQIINRHKF 162 Query: 483 SERAAATICRGVVNVVNVCHFMGVMHRDL 569 E AA I + +++ + H ++HRD+ Sbjct: 163 DECDAANIMKQILSGICYLHKHNIVHRDI 191 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 90,639,858 Number of Sequences: 219361 Number of extensions: 2078732 Number of successful extensions: 8675 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 7492 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 8125 length of database: 80,573,946 effective HSP length: 106 effective length of database: 57,321,680 effective search space used: 4757699440 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
