ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bags7m19 |
|---|---|
| Clone Library Name | barley_pub |
>LEU32_ARATH (P93832) 3-isopropylmalate dehydrogenase 2, chloroplast precursor| (EC 1.1.1.85) (Beta-IPM dehydrogenase 2) (IMDH 2) (3-IPM-DH 2) Length = 405 Score = 312 bits (799), Expect = 4e-85 Identities = 158/179 (88%), Positives = 168/179 (93%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL IRA L VFANLRPATVLPQLVDASTLKREVAEGVD+MVVRELTGGIYFG+PRG T Sbjct: 131 GLLQIRAALKVFANLRPATVLPQLVDASTLKREVAEGVDLMVVRELTGGIYFGEPRGIKT 190 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 N+ GEE GFNTE+Y+ EIDRIARVAFE ARKR GKLCSVDKANVLEAS+LWRKRVTA+A Sbjct: 191 NENGEEVGFNTEVYAAHEIDRIARVAFETARKRRGKLCSVDKANVLEASILWRKRVTALA 250 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 SE+PDVELSHMYVDNAAMQLVR+PKQFDTIVTNNIFGDILSDEASMITGSIGMLPSAS+ Sbjct: 251 SEYPDVELSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASL 309
>LEU3_BRANA (P29102) 3-isopropylmalate dehydrogenase, chloroplast precursor (EC| 1.1.1.85) (Beta-IPM dehydrogenase) (IMDH) (3-IPM-DH) Length = 406 Score = 310 bits (793), Expect = 2e-84 Identities = 155/180 (86%), Positives = 169/180 (93%) Frame = +2 Query: 2 TGLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFG 181 TGLL +RAGL VFANLRPATVLPQLVDASTLKREVAEGVD+MVVRELTGGIYFG PRG Sbjct: 131 TGLLQLRAGLKVFANLRPATVLPQLVDASTLKREVAEGVDLMVVRELTGGIYFGVPRGIK 190 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI 361 TN+ GEE G+NTE+Y+ EIDRIARVAFE ARKR GKLCSVDKANVL+AS+LWR+RVTA+ Sbjct: 191 TNENGEEVGYNTEVYAAHEIDRIARVAFETARKRRGKLCSVDKANVLDASILWRRRVTAL 250 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 A+E+PDVELSHMYVDNAAMQLVR+PKQFDTIVTNNIFGDILSDEASMITGSIGMLPSAS+ Sbjct: 251 AAEYPDVELSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASL 310
>LEU31_ARATH (Q9SA14) 3-isopropylmalate dehydrogenase 1, chloroplast precursor| (EC 1.1.1.85) (Beta-IPM dehydrogenase 1) (IMDH 1) (3-IPM-DH 1) Length = 406 Score = 309 bits (791), Expect = 4e-84 Identities = 155/180 (86%), Positives = 168/180 (93%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLLNIR L VFANLRPATVLPQLVDASTLK+EVA+GVD+M+VRELTGGIYFG+PRG Sbjct: 132 GLLNIRRDLNVFANLRPATVLPQLVDASTLKKEVAQGVDMMIVRELTGGIYFGEPRGITI 191 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 N+ GEE GFNTEIY+ EIDRIARVAFE ARKR GKLCSVDKANVL+AS+LWRKRVTA+A Sbjct: 192 NENGEEVGFNTEIYAAHEIDRIARVAFETARKRRGKLCSVDKANVLDASILWRKRVTALA 251 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASVG 544 SE+PDVELSHMYVDNAAMQLVR+PKQFDTIVTNNIFGDILSDEASMITGSIGMLPSAS+G Sbjct: 252 SEYPDVELSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLG 311
>LEU33_ARATH (Q9FMT1) 3-isopropylmalate dehydrogenase 3, chloroplast precursor| (EC 1.1.1.85) (Beta-IPM dehydrogenase 3) (IMDH 3) (3-IPM-DH 3) Length = 409 Score = 296 bits (759), Expect = 2e-80 Identities = 149/179 (83%), Positives = 164/179 (91%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTN 187 L +R L VFANLRPATVLPQLVDASTLK+EVAEGVD+M+VRELTGGIYFG+PRG N Sbjct: 136 LFYLRRDLKVFANLRPATVLPQLVDASTLKKEVAEGVDMMIVRELTGGIYFGEPRGITIN 195 Query: 188 DKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIAS 367 + GEE G +TEIY+ EIDRIARVAFE ARKR GKLCSVDKANVL+AS+LWRKRVTA+AS Sbjct: 196 ENGEEVGVSTEIYAAHEIDRIARVAFETARKRRGKLCSVDKANVLDASILWRKRVTALAS 255 Query: 368 EFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASVG 544 E+PDVELSHMYVDNAAMQL+R+PKQFDTIVTNNIFGDILSDEASMITGSIGMLPSAS+G Sbjct: 256 EYPDVELSHMYVDNAAMQLIRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLG 314
>LEU3_ANASP (Q8YXA2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 280 bits (716), Expect = 2e-75 Identities = 137/180 (76%), Positives = 157/180 (87%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL +RAGL +FANLRPA +LPQL+DASTLKREV EGVDIMVVRELTGGIYFGKPRG T Sbjct: 93 GLLGLRAGLELFANLRPAQILPQLIDASTLKREVVEGVDIMVVRELTGGIYFGKPRGIFT 152 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + GE+ G NT +Y+ +EIDRI R+AFE ARKR GKLCSVDKANVL+ S LWR R+T ++ Sbjct: 153 TETGEKRGVNTMVYTESEIDRIGRIAFETARKRRGKLCSVDKANVLDVSQLWRDRITNLS 212 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASVG 544 E+PDVELSH+YVDNAAMQLVR PKQFDTIVT N+FGDILSD A+M+TGSIGMLPSAS+G Sbjct: 213 QEYPDVELSHLYVDNAAMQLVRAPKQFDTIVTGNLFGDILSDAAAMLTGSIGMLPSASLG 272
>LEU3_SYNY3 (P73960) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 278 bits (711), Expect = 7e-75 Identities = 138/181 (76%), Positives = 158/181 (87%) Frame = +2 Query: 2 TGLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFG 181 TGLL IR GLG+FANLRPAT+ PQL+DAS+LKREV EGVDIMVVRELTGGIYFGKP+G Sbjct: 92 TGLLAIREGLGLFANLRPATIFPQLIDASSLKREVVEGVDIMVVRELTGGIYFGKPKGIF 151 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI 361 + GE+ G NT Y+V EIDRIA+VAFE ARKR G+LCSVDKANVL+ S LWR RV AI Sbjct: 152 ETETGEKRGVNTMAYTVGEIDRIAKVAFETARKRRGQLCSVDKANVLDVSQLWRDRVMAI 211 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 A ++PDVELSH+YVDNAAMQLVR+P+QFDTIVT N+FGDILSD A+M+TGSIGMLPSAS+ Sbjct: 212 AVDYPDVELSHLYVDNAAMQLVRSPRQFDTIVTGNLFGDILSDIAAMLTGSIGMLPSASL 271 Query: 542 G 544 G Sbjct: 272 G 272
>LEU3_SYNP6 (Q5MZ40) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 365 Score = 271 bits (693), Expect = 9e-73 Identities = 133/181 (73%), Positives = 157/181 (86%) Frame = +2 Query: 2 TGLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFG 181 TGLL +RAGLG+FANLRPA +LPQLVDAS+LKREV EGVD+MVVRELTGGIYFG+P+G Sbjct: 92 TGLLGLRAGLGLFANLRPAAILPQLVDASSLKREVIEGVDLMVVRELTGGIYFGEPKGCF 151 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI 361 +++G + FNT +Y EIDRI RVAF++ARKRG +LCSVDKANVLE S LWR R+T + Sbjct: 152 ADEQGRQRAFNTMVYREDEIDRIGRVAFDIARKRGKRLCSVDKANVLEVSQLWRDRMTLL 211 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 S++ DVELSH+YVDNAAMQLVR PKQFDTIVT N+FGDILSD A+M+TGSIGMLPSAS+ Sbjct: 212 GSDYADVELSHLYVDNAAMQLVRWPKQFDTIVTGNLFGDILSDIAAMLTGSIGMLPSASL 271 Query: 542 G 544 G Sbjct: 272 G 272
>LEU3_SYNEL (P59029) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 361 Score = 270 bits (690), Expect = 2e-72 Identities = 133/181 (73%), Positives = 156/181 (86%) Frame = +2 Query: 2 TGLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFG 181 TGLL +R+GLG+FANLRPA + PQL+ AS+LK EV GVD+MVVRELTGGIYFG+PRG Sbjct: 92 TGLLALRSGLGLFANLRPAKIFPQLLHASSLKPEVIAGVDLMVVRELTGGIYFGQPRGIF 151 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI 361 T + GE+ G NT Y+ EIDRI RVAFE ARKR GKLCSVDKANVLE S LWR R+TA+ Sbjct: 152 TTETGEQRGVNTMAYTATEIDRIGRVAFETARKRQGKLCSVDKANVLEVSQLWRDRLTAL 211 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 ++E+PDVEL+H+YVDNAAMQLVR PKQFDTIVT+N+FGDILSD A+M+TGSIGMLPSAS+ Sbjct: 212 SAEYPDVELTHLYVDNAAMQLVRAPKQFDTIVTSNLFGDILSDIAAMLTGSIGMLPSASL 271 Query: 542 G 544 G Sbjct: 272 G 272
>LEU3_PROMM (Q7V842) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 259 bits (662), Expect = 3e-69 Identities = 129/181 (71%), Positives = 154/181 (85%) Frame = +2 Query: 2 TGLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFG 181 TGLL++RAGL +FANLRP T+LP L+DAS+LK V +GVD+MVVRELTGGIYFG+P+G Sbjct: 91 TGLLSLRAGLKLFANLRPVTILPALIDASSLKANVIKGVDLMVVRELTGGIYFGQPKGRI 150 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI 361 D G+E FNT YS E+DRIA+VAFE+AR R GKLCSVDKANVL+ S LWR RV A+ Sbjct: 151 EAD-GDERAFNTMTYSRTEVDRIAKVAFELARDRSGKLCSVDKANVLDVSQLWRDRVDAL 209 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 A+ + DVELSHMYVDNAAMQLVRNP+QFD ++T N+FGDILSDEA+M+TGSIGMLPSAS+ Sbjct: 210 AANYGDVELSHMYVDNAAMQLVRNPRQFDVLLTGNLFGDILSDEAAMLTGSIGMLPSASL 269 Query: 542 G 544 G Sbjct: 270 G 270
>LEU3_GLOVI (Q7NFH4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 257 bits (656), Expect = 2e-68 Identities = 129/179 (72%), Positives = 147/179 (82%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTN 187 LL +RAGLG+FANLRPA +LPQLV AS LK EV EGVDI+VVRELTGG+YFG P+G Sbjct: 94 LLGLRAGLGLFANLRPARILPQLVAASALKPEVVEGVDILVVRELTGGLYFGIPKGIFPE 153 Query: 188 DKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIAS 367 KG G NT YS EI+RI RVAFE AR+R GKLCSVDKANVLE S LWR+ + +A Sbjct: 154 KKGGRRGVNTMSYSAFEIERIGRVAFEAARERRGKLCSVDKANVLEVSQLWREVLVGLAP 213 Query: 368 EFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASVG 544 E+PDVEL+HMYVDN AMQLVR P+QFDTIVT N+FGDILSDEA+M+TGSIGMLPSAS+G Sbjct: 214 EYPDVELTHMYVDNCAMQLVRRPRQFDTIVTENMFGDILSDEAAMLTGSIGMLPSASLG 272
>LEU3_SYNPX (Q7U840) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 251 bits (642), Expect = 7e-67 Identities = 124/181 (68%), Positives = 153/181 (84%) Frame = +2 Query: 2 TGLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFG 181 TGLL +R+G+ +FANLRP ++P L+ AS+L+ EV EGVD+MVVRELTGGIYFG+P+G Sbjct: 91 TGLLGLRSGMALFANLRPVKIVPALIGASSLRPEVIEGVDLMVVRELTGGIYFGQPKGRI 150 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI 361 D GEE GFNT YS +E+DRIARVAF++AR+R G LCSVDKANVL+ S LWR RV A+ Sbjct: 151 QAD-GEERGFNTMTYSSSEVDRIARVAFDLARERRGNLCSVDKANVLDVSQLWRDRVDAM 209 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 A + DVE+SHMYVDNAAMQLVR+P+QFD ++T N+FGDILSDEA+M+TGSIGMLPSAS+ Sbjct: 210 APAYSDVEVSHMYVDNAAMQLVRSPRQFDVLLTGNLFGDILSDEAAMLTGSIGMLPSASL 269 Query: 542 G 544 G Sbjct: 270 G 270
>LEU3_SPIPL (Q00412) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 355 Score = 251 bits (640), Expect = 1e-66 Identities = 124/181 (68%), Positives = 148/181 (81%) Frame = +2 Query: 2 TGLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFG 181 TGLL +RAGLG+FAN P ++DAS+LKREV EGVDIMVVRELTGGIYFG+P+G Sbjct: 92 TGLLALRAGLGLFANRARLLFCPHVLDASSLKREVVEGVDIMVVRELTGGIYFGQPKGIF 151 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI 361 + G+ G NT Y +EIDRI RV FE A+KR G+LCSVDKANVL+ S LWR R+ A+ Sbjct: 152 ETETGKNEGSNTMAYGESEIDRIGRVGFETAKKRQGRLCSVDKANVLDVSQLWRDRIMAL 211 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 A+++P+VELSH+YVDNAAMQLVR PKQFDTIVT N+FGDILSD A+M+TGSIGMLPSAS+ Sbjct: 212 AADYPEVELSHLYVDNAAMQLVRWPKQFDTIVTGNLFGDILSDAAAMLTGSIGMLPSASL 271 Query: 542 G 544 G Sbjct: 272 G 272
>LEU3_NITOC (Q3JCC4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 246 bits (629), Expect = 2e-65 Identities = 123/179 (68%), Positives = 149/179 (83%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL IR+ LG+FANLRPA + PQLV ASTLK EV G+D+M+VRELTGGIYFG+PRG Sbjct: 91 GLLGIRSALGLFANLRPAILYPQLVGASTLKPEVVSGLDLMIVRELTGGIYFGQPRGVCR 150 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + GE GFNT +Y +EI RIA+VAF +A KR ++CSVDKANVLEA+ LWR+ ++ +A Sbjct: 151 LEHGERQGFNTLVYKESEIRRIAQVAFTIAMKRDRRVCSVDKANVLEATELWREVMSEVA 210 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 +EFP+VELSHMYVDNAAMQLVR PKQFD +VT N+FGDILSD A+M+TGSIGMLPSAS+ Sbjct: 211 AEFPEVELSHMYVDNAAMQLVRAPKQFDVVVTTNMFGDILSDCAAMLTGSIGMLPSASL 269
>LEU3_PSEF5 (Q4KF05) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 360 Score = 246 bits (627), Expect = 4e-65 Identities = 124/179 (69%), Positives = 146/179 (81%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL IRA LG+F NLRPA + PQL DAS+LK E+ G+DI++VRELTGGIYFG PRG Sbjct: 91 GLLKIRAQLGLFGNLRPAILYPQLADASSLKPEIVSGLDILIVRELTGGIYFGAPRGTRE 150 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + GE ++T YS +EI RIARV F++AR RG KLCSVDKANVL +S LWR+ V +A Sbjct: 151 LENGERQSYDTLPYSESEIRRIARVGFDMARVRGKKLCSVDKANVLASSQLWREVVEQVA 210 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 ++PDVELSHMYVDNAAMQLVR PKQFD IVT+N+FGDILSDEASM+TGSIGMLPSAS+ Sbjct: 211 KDYPDVELSHMYVDNAAMQLVRAPKQFDVIVTDNMFGDILSDEASMLTGSIGMLPSASL 269
>LEU3_XANCP (Q8P5L1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 244 bits (624), Expect = 9e-65 Identities = 122/179 (68%), Positives = 146/179 (81%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL IR+ LG+FANLRPA + PQL DASTLK EV G+D++++RELTGGIYFG+PRG T Sbjct: 91 GLLKIRSQLGLFANLRPALLYPQLADASTLKPEVVSGLDLLILRELTGGIYFGQPRGTRT 150 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 D GE ++T YS +EI RIA+ FE+AR RG KLCSVDKANVL +S LWR V +A Sbjct: 151 LDNGERQAYDTLPYSESEIRRIAKAGFEMARLRGKKLCSVDKANVLASSQLWRAVVEEVA 210 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 ++PD+ LSHMYVDNAAMQLVR PKQFD IVT+N+FGDILSD+ASM+TGSIGMLPSAS+ Sbjct: 211 KDYPDIALSHMYVDNAAMQLVRAPKQFDVIVTDNMFGDILSDQASMLTGSIGMLPSASL 269
>LEU3_XANC8 (Q4UYG2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 244 bits (624), Expect = 9e-65 Identities = 122/179 (68%), Positives = 146/179 (81%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL IR+ LG+FANLRPA + PQL DASTLK EV G+D++++RELTGGIYFG+PRG T Sbjct: 91 GLLKIRSQLGLFANLRPALLYPQLADASTLKPEVVSGLDLLILRELTGGIYFGQPRGTRT 150 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 D GE ++T YS +EI RIA+ FE+AR RG KLCSVDKANVL +S LWR V +A Sbjct: 151 LDNGERQAYDTLPYSESEIRRIAKAGFEMARLRGKKLCSVDKANVLASSQLWRAVVEEVA 210 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 ++PD+ LSHMYVDNAAMQLVR PKQFD IVT+N+FGDILSD+ASM+TGSIGMLPSAS+ Sbjct: 211 KDYPDIALSHMYVDNAAMQLVRAPKQFDVIVTDNMFGDILSDQASMLTGSIGMLPSASL 269
>LEU3_METCA (Q606F4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 360 Score = 244 bits (623), Expect = 1e-64 Identities = 120/179 (67%), Positives = 147/179 (82%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL +R+ L +F+NLRPA + PQLV ASTLK EV G+DIM+VRELTGGIYFGKPRG Sbjct: 91 GLLGLRSELELFSNLRPAVLYPQLVSASTLKPEVVAGLDIMIVRELTGGIYFGKPRGRRI 150 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 N+ GE G+NT +YS +EI RIA AF++ARKR +LCS+DKANVLE + LWR+ V + Sbjct: 151 NEDGEREGYNTLVYSESEIRRIAHSAFQIARKRNRRLCSIDKANVLECTELWREVVIEVG 210 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 ++PDV LSHMYVDNAAMQLVRNPKQFD ++T+N+FGDILSD A+M+TGSIGMLPSAS+ Sbjct: 211 KDYPDVALSHMYVDNAAMQLVRNPKQFDVMLTDNMFGDILSDCAAMLTGSIGMLPSASL 269
>LEU3_ACIAD (Q6FEV6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 359 Score = 244 bits (622), Expect = 1e-64 Identities = 119/180 (66%), Positives = 151/180 (83%), Gaps = 1/180 (0%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL IR+ L +FANLRPA + PQL DAS+LK E+ G+DI++VRELTGGIYFG+PRG Sbjct: 91 GLLKIRSELNLFANLRPALLYPQLADASSLKPEIVAGLDILIVRELTGGIYFGQPRGIRE 150 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI- 361 + GE+ G+NT++YS +EI RIA+VAFE+A RG K+CSVDKANVLE + LW++ VT + Sbjct: 151 LENGEKQGYNTDVYSESEIKRIAKVAFELAALRGSKVCSVDKANVLEVTELWKQTVTELQ 210 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 +++P+++LSHMYVDNAAMQLVR PKQFD IVT N+FGDILSDEA+M+TGSIGMLPSAS+ Sbjct: 211 QAQYPNIQLSHMYVDNAAMQLVRAPKQFDVIVTGNLFGDILSDEAAMLTGSIGMLPSASL 270
>LEU3_XANC5 (Q3BPJ8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 244 bits (622), Expect = 1e-64 Identities = 122/179 (68%), Positives = 146/179 (81%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL IR+ LG+FANLRPA + PQL DASTLK EV G+D++++RELTGGIYFG+PRG T Sbjct: 91 GLLKIRSQLGLFANLRPALLYPQLADASTLKPEVVAGLDLLILRELTGGIYFGQPRGNRT 150 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 D GE ++T YS +EI RIA+ FE+AR RG KLCSVDKANVL +S LWR V +A Sbjct: 151 LDNGERQAYDTLPYSESEIRRIAKAGFEMARLRGKKLCSVDKANVLASSQLWRAVVEEVA 210 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 ++PD+ LSHMYVDNAAMQLVR PKQFD IVT+N+FGDILSD+ASM+TGSIGMLPSAS+ Sbjct: 211 KDYPDIALSHMYVDNAAMQLVRAPKQFDVIVTDNMFGDILSDQASMLTGSIGMLPSASL 269
>LEU3_XANOR (Q5H4C7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 243 bits (621), Expect = 2e-64 Identities = 122/179 (68%), Positives = 146/179 (81%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL IR+ LG+FANLRPA + PQL DASTLK EV G+D++++RELTGGIYFG+PRG T Sbjct: 91 GLLKIRSQLGLFANLRPALLYPQLADASTLKPEVVAGLDLLILRELTGGIYFGQPRGNRT 150 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 D GE ++T YS +EI RIA+ FE+AR RG KLCSVDKANVL +S LWR V +A Sbjct: 151 LDNGERQAYDTLPYSESEICRIAKAGFEMARLRGKKLCSVDKANVLASSQLWRAVVEEVA 210 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 ++PD+ LSHMYVDNAAMQLVR PKQFD IVT+N+FGDILSD+ASM+TGSIGMLPSAS+ Sbjct: 211 KDYPDIALSHMYVDNAAMQLVRAPKQFDVIVTDNMFGDILSDQASMLTGSIGMLPSASL 269
>LEU3_PSEPK (Q88LE5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 360 Score = 243 bits (620), Expect = 3e-64 Identities = 122/179 (68%), Positives = 147/179 (82%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL IR+ LG+FANLRPA + PQL DAS+LK E+ G+DI++VRELTGGIYFG PRG Sbjct: 91 GLLKIRSQLGLFANLRPAILYPQLADASSLKPEIVSGLDILIVRELTGGIYFGAPRGQRE 150 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + GE ++T YS +E+ RIARV F++AR RG KLCSVDKANVL +S LWR+ V +A Sbjct: 151 LEGGERQAYDTLPYSESEVRRIARVGFDMARVRGKKLCSVDKANVLASSQLWREVVEDVA 210 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 ++PDVELSHMYVDNAAMQLVR PKQFD +VT+N+FGDILSDEASM+TGSIGMLPSAS+ Sbjct: 211 KDYPDVELSHMYVDNAAMQLVRAPKQFDVMVTDNMFGDILSDEASMLTGSIGMLPSASL 269
>LEU3_XANAC (Q8PH05) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 243 bits (619), Expect = 3e-64 Identities = 121/179 (67%), Positives = 146/179 (81%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL IR+ LG+FANLRPA + PQL DASTLK EV G+D++++RELTGGIYFG+PRG T Sbjct: 91 GLLKIRSQLGLFANLRPALLYPQLADASTLKPEVVAGLDLLILRELTGGIYFGQPRGNRT 150 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 D GE ++T YS +EI RIA+ F++AR RG KLCSVDKANVL +S LWR V +A Sbjct: 151 LDNGERQAYDTLPYSESEIRRIAKAGFDMARLRGKKLCSVDKANVLASSQLWRAVVEEVA 210 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 ++PD+ LSHMYVDNAAMQLVR PKQFD IVT+N+FGDILSD+ASM+TGSIGMLPSAS+ Sbjct: 211 KDYPDIALSHMYVDNAAMQLVRAPKQFDVIVTDNMFGDILSDQASMLTGSIGMLPSASL 269
>LEU3_CHRVO (Q7NUC2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 354 Score = 241 bits (616), Expect = 7e-64 Identities = 121/179 (67%), Positives = 142/179 (79%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL IR L +FANLRPA + P+L +ASTLK EV G+DIM+VRELTG IYFG+PRG Sbjct: 88 GLLAIRKDLNLFANLRPAILYPELANASTLKPEVVAGLDIMIVRELTGDIYFGQPRGIAV 147 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 N+ GE +NT YS +E+ RIA VAF +A KR KLCSVDKANVLE + W++ + +A Sbjct: 148 NELGEREAYNTMRYSESEVRRIAHVAFGIAMKRNRKLCSVDKANVLETTEFWKEIMIEVA 207 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 E+P VELSHMYVDNAAMQLVRNPKQFD +VT NIFGDILSDEASM+TGSIGMLPSAS+ Sbjct: 208 KEYPQVELSHMYVDNAAMQLVRNPKQFDVMVTGNIFGDILSDEASMLTGSIGMLPSASL 266
>LEU3_PSEU2 (Q4ZUZ4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 360 Score = 241 bits (615), Expect = 1e-63 Identities = 121/179 (67%), Positives = 145/179 (81%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL IR+ LG+F NLRPA + PQL DAS+LK E+ G+DIM+VRELTGGIYFG PRG Sbjct: 91 GLLKIRSQLGLFGNLRPAILYPQLADASSLKPEIVAGLDIMIVRELTGGIYFGAPRGTRV 150 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 D GE ++T YS +EI RIA+V F++A RG KLCSVDKANVL +S LWR+ V +A Sbjct: 151 LDNGERQAYDTLPYSESEIRRIAKVGFDMAMVRGKKLCSVDKANVLASSQLWREIVEQVA 210 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 ++P+VELSHMYVDNAAMQLVR PKQFD IVT+N+FGDILSD+ASM+TGSIGMLPSAS+ Sbjct: 211 RDYPEVELSHMYVDNAAMQLVRAPKQFDVIVTDNLFGDILSDQASMLTGSIGMLPSASL 269
>LEU3_PSE14 (Q48K97) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 360 Score = 240 bits (613), Expect = 2e-63 Identities = 120/179 (67%), Positives = 145/179 (81%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL IR+ LG+F NLRPA + PQL DAS+LK E+ G+DI++VRELTGGIYFG PRG Sbjct: 91 GLLKIRSQLGLFGNLRPAILYPQLADASSLKPEIVAGLDILIVRELTGGIYFGAPRGTRV 150 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 D GE ++T YS +EI RIA+V F++A RG KLCSVDKANVL +S LWR+ V +A Sbjct: 151 LDNGERQAYDTLPYSESEIRRIAKVGFDMAMVRGKKLCSVDKANVLASSQLWREIVEQVA 210 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 ++P+VELSHMYVDNAAMQLVR PKQFD IVT+N+FGDILSD+ASM+TGSIGMLPSAS+ Sbjct: 211 KDYPEVELSHMYVDNAAMQLVRAPKQFDVIVTDNLFGDILSDQASMLTGSIGMLPSASL 269
>LEU3_XYLFA (Q9PAX3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 240 bits (613), Expect = 2e-63 Identities = 122/179 (68%), Positives = 143/179 (79%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL IRA LG+FANLRPA + PQL DASTLK EV G+DI++VRELTGG+YFG+PRG Sbjct: 91 GLLKIRAQLGLFANLRPALLYPQLADASTLKPEVVAGLDILIVRELTGGLYFGQPRGSRI 150 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + GE F+T Y +EI RI +V FE+AR RG KLCSVDKANVL +S LWR +A Sbjct: 151 SKNGEREAFDTLPYCESEIRRILKVGFEMARLRGKKLCSVDKANVLASSQLWRTVAGEMA 210 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 ++PDV LSHMYVDNAAMQLVR+PKQFD IVT N+FGDILSD+ASM+TGSIGMLPSAS+ Sbjct: 211 KDYPDVTLSHMYVDNAAMQLVRHPKQFDVIVTENMFGDILSDQASMLTGSIGMLPSASL 269
>LEU3_PSESM (Q884C0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 360 Score = 239 bits (610), Expect = 4e-63 Identities = 119/179 (66%), Positives = 145/179 (81%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL IR+ LG+F NLRPA + PQL DAS+LK E+ G+DI++VRELTGGIYFG PRG Sbjct: 91 GLLKIRSQLGLFGNLRPAILYPQLADASSLKPEIVAGLDILIVRELTGGIYFGAPRGTRV 150 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 D GE ++T YS +EI RIA+V F++A RG KLCSVDKANVL +S LWR+ V +A Sbjct: 151 LDNGERQAYDTLPYSESEIRRIAKVGFDMAMVRGKKLCSVDKANVLASSQLWREIVEQVA 210 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 ++P+VELSH+YVDNAAMQLVR PKQFD IVT+N+FGDILSD+ASM+TGSIGMLPSAS+ Sbjct: 211 KDYPEVELSHLYVDNAAMQLVRAPKQFDVIVTDNLFGDILSDQASMLTGSIGMLPSASL 269
>LEU3_XYLFT (Q87BQ1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 239 bits (610), Expect = 4e-63 Identities = 122/179 (68%), Positives = 142/179 (79%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL IRA LG+FANLRPA + PQL DASTLK EV G+DI++VRELTGG+YFG+PRG Sbjct: 91 GLLKIRAQLGLFANLRPALLYPQLADASTLKPEVVAGLDILIVRELTGGLYFGQPRGSRI 150 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + GE F+T Y +EI RI +V FE+AR RG KLCSVDKANVL +S LWR +A Sbjct: 151 SKNGEREAFDTLPYCESEIRRILKVGFEMARLRGKKLCSVDKANVLASSQLWRTVAGEMA 210 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 ++PDV LSHMYVDNAAMQLVR PKQFD IVT N+FGDILSD+ASM+TGSIGMLPSAS+ Sbjct: 211 KDYPDVTLSHMYVDNAAMQLVRYPKQFDVIVTENMFGDILSDQASMLTGSIGMLPSASL 269
>LEU3_AZOSE (Q5P1J6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 350 Score = 239 bits (609), Expect = 5e-63 Identities = 123/179 (68%), Positives = 143/179 (79%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL IR LG+FANLRPA + P+L +AS+LK EV G+DI++VRELTG IYFG+PRG Sbjct: 85 GLLGIRKDLGLFANLRPAILYPELANASSLKPEVVAGLDILIVRELTGDIYFGQPRGLEV 144 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 D GE GFNT YS +EI RI RVAFE ARKR +LCSVDK NVLE + LWR + +A Sbjct: 145 RD-GERFGFNTMHYSESEIRRIGRVAFEAARKRNRRLCSVDKMNVLETTQLWRDVMIELA 203 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 +E+PDVELSHM VDNAAMQLVR PKQFD +VT N+FGDILSDEASM+TGSIGMLPSAS+ Sbjct: 204 AEYPDVELSHMLVDNAAMQLVRAPKQFDVMVTGNMFGDILSDEASMLTGSIGMLPSASL 262
>LEU3_THIDA (Q3SHL3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 353 Score = 238 bits (607), Expect = 8e-63 Identities = 118/179 (65%), Positives = 145/179 (81%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL IR L +FANLRPA + P+L AS+LK EV G+D+M+VRELTG +YFG+PRG T Sbjct: 88 GLLRIRKELNLFANLRPALLYPELASASSLKPEVVSGLDLMIVRELTGDVYFGQPRGIET 147 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + GE GFNT +YS +E+ R+A VAF +A KRG KLCSV+KANVLE S LW++ + +A Sbjct: 148 RN-GERVGFNTMLYSESEVRRVAHVAFGIAMKRGKKLCSVEKANVLECSELWKEIMIEVA 206 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 ++P+VELSHMYVDNAAMQL+R PKQFDTIVT NIFGDILSD ASM++GSIGMLPSAS+ Sbjct: 207 KDYPEVELSHMYVDNAAMQLIRAPKQFDTIVTGNIFGDILSDAASMLSGSIGMLPSASL 265
>LEU3_WOLSU (Q7M886) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 237 bits (605), Expect = 1e-62 Identities = 116/181 (64%), Positives = 146/181 (80%) Frame = +2 Query: 2 TGLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFG 181 +GLL +R L +FANLRP V +L++ASTLK V +GVDI+VVREL GGIYFG+P+G Sbjct: 91 SGLLKLRKSLEIFANLRPTVVYDELIEASTLKESVIKGVDILVVRELIGGIYFGEPKG-- 148 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI 361 + + FNT +YSV EI+RIA VAF+ A +R ++CSVDKANVL+ S LWR+ VT I Sbjct: 149 ---REGDKAFNTMVYSVPEIERIAHVAFKAAMRRQKRVCSVDKANVLDVSQLWRETVTRI 205 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 A E+P+VELSHMY+DNAAMQL+RNPKQFD I+T N+FGDILSDEASM++GSIG+LPSAS+ Sbjct: 206 AKEYPEVELSHMYIDNAAMQLIRNPKQFDVILTGNLFGDILSDEASMLSGSIGLLPSASI 265 Query: 542 G 544 G Sbjct: 266 G 266
>LEU3_PSEAE (Q51375) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 360 Score = 237 bits (604), Expect = 2e-62 Identities = 120/179 (67%), Positives = 145/179 (81%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL IR+ LG+FANLRPA + PQL AS+LK EV G+DI++VRELTGGIYFG+PR Sbjct: 91 GLLKIRSQLGLFANLRPAILYPQLAAASSLKPEVVAGLDILIVRELTGGIYFGQPREQRV 150 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + GE ++T YS +EI RIARV F++AR R +LCSVDKANVL +S LWR+ V +A Sbjct: 151 LENGERQAYDTLPYSESEIRRIARVGFDMARVRNNRLCSVDKANVLASSQLWREVVEEVA 210 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 ++PDVELSHMYVDNAAMQLVR PKQFD +VT+N+FGDILSDEASM+TGSIGMLPSAS+ Sbjct: 211 KDYPDVELSHMYVDNAAMQLVRAPKQFDVMVTDNMFGDILSDEASMLTGSIGMLPSASL 269
>LEU3_NEIMB (Q9JZI9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 356 Score = 236 bits (601), Expect = 4e-62 Identities = 120/179 (67%), Positives = 140/179 (78%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL IR L +FANLRPA + P+L +ASTLK E+ G+DI++VRELTG IYFG+PRG Sbjct: 90 GLLAIRKDLNLFANLRPAVLYPELANASTLKPEIVAGLDILIVRELTGDIYFGEPRGIRV 149 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + GE G+NT YS +EI RIA VAF+ A+KR K+CSV KANVLE + LWR+ I Sbjct: 150 LENGEREGYNTMKYSESEIRRIAHVAFQSAQKRSKKVCSVGKANVLETTELWREIFEEIG 209 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 E+PDVELSHMYVDNAAMQLVR PKQFD I T NIFGDILSDEASM+TGSIGMLPSAS+ Sbjct: 210 KEYPDVELSHMYVDNAAMQLVRAPKQFDVIATGNIFGDILSDEASMLTGSIGMLPSASL 268
>LEU3_NEIMA (Q9JU79) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 356 Score = 236 bits (601), Expect = 4e-62 Identities = 120/179 (67%), Positives = 140/179 (78%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL IR L +FANLRPA + P+L +ASTLK E+ G+DI++VRELTG IYFG+PRG Sbjct: 90 GLLAIRKDLNLFANLRPAILYPELANASTLKSEIVAGLDILIVRELTGDIYFGEPRGIRV 149 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + GE G+NT YS +EI RIA VAF+ A+KR K+CSV KANVLE + LWR+ I Sbjct: 150 LENGEREGYNTMKYSESEIRRIAHVAFQSAQKRSKKVCSVGKANVLETTELWREIFEEIG 209 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 E+PDVELSHMYVDNAAMQLVR PKQFD I T NIFGDILSDEASM+TGSIGMLPSAS+ Sbjct: 210 KEYPDVELSHMYVDNAAMQLVRAPKQFDVIATGNIFGDILSDEASMLTGSIGMLPSASL 268
>LEU3_NITEU (Q82WI6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 356 Score = 235 bits (600), Expect = 5e-62 Identities = 120/179 (67%), Positives = 141/179 (78%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL IR L +FANLRP + P+L +ASTLK EV G+DI++VRELTG IYFG+PRG Sbjct: 88 GLLAIRKELNLFANLRPVVLYPELSNASTLKPEVVAGLDILIVRELTGDIYFGRPRGIEY 147 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 D G++ GFNT IYS +EI RIA VAF+ A +R G+LCSVDK NVLE + LWR VT A Sbjct: 148 RD-GQKVGFNTMIYSESEIRRIAHVAFQAAGRRNGRLCSVDKMNVLECTQLWRDVVTETA 206 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 +PDV LSHM VDNAAMQLVRNP+QFD +VT N+FGDILSDEASM+TGSIGMLPSAS+ Sbjct: 207 QSYPDVTLSHMLVDNAAMQLVRNPRQFDVVVTGNMFGDILSDEASMLTGSIGMLPSASL 265
>LEU3_NEILA (P50180) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) (Fragment) Length = 313 Score = 235 bits (599), Expect = 7e-62 Identities = 119/179 (66%), Positives = 140/179 (78%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL IR L +FANLRPA + P+L +ASTLK E+ G+DI++VRELTG IYFG+PRG Sbjct: 90 GLLAIRKDLNLFANLRPAVLYPELANASTLKPEIVAGLDILIVRELTGDIYFGEPRGIRV 149 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + GE G+NT YS +EI RIA VAF+ A+KR K+CSV KANVLE + LWR+ I Sbjct: 150 LENGEREGYNTMKYSESEIRRIAHVAFQSAQKRSKKVCSVGKANVLETTELWREIFEEIG 209 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 E+PDVELSHMYVDNAAMQLVR PKQFD I T NIFGDILSDEASM+TGS+GMLPSAS+ Sbjct: 210 KEYPDVELSHMYVDNAAMQLVRAPKQFDVIATGNIFGDILSDEASMLTGSLGMLPSASL 268
>LEU3_NEIG1 (Q5F8T6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 356 Score = 234 bits (598), Expect = 9e-62 Identities = 119/179 (66%), Positives = 140/179 (78%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL IR L +FANLRPA + P+L +ASTLK E+ G+DI++VRELTG IYFG+PRG Sbjct: 90 GLLAIRKDLNLFANLRPAVLYPELANASTLKPEIVAGLDILIVRELTGDIYFGEPRGIRV 149 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + GE G+NT YS +EI RIA VAF+ A+KR K+CSV KANVLE + LWR+ I Sbjct: 150 LENGEHEGYNTMKYSESEIRRIAHVAFQSAQKRSKKVCSVGKANVLETTELWREIFEEIG 209 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 ++PDVELSHMYVDNAAMQLVR PKQFD I T NIFGDILSDEASM+TGSIGMLPSAS+ Sbjct: 210 KQYPDVELSHMYVDNAAMQLVRAPKQFDVIATGNIFGDILSDEASMLTGSIGMLPSASL 268
>LEU3_BORPA (Q7W929) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 231 bits (590), Expect = 8e-61 Identities = 115/182 (63%), Positives = 141/182 (77%), Gaps = 4/182 (2%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTN 187 +L +R LG+FANLRPA + P+L AS+LK E+ G+DI+++RELTG IYFG PRG T Sbjct: 88 ILGLRKALGLFANLRPAILYPELASASSLKPEIVSGLDILIIRELTGDIYFGTPRGVRTA 147 Query: 188 DKG----EETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVT 355 G E G++T Y+ +E+ RIAR+ FE ARKR KLCSVDKANVLE S WR V Sbjct: 148 ADGAFAGEREGYDTMRYAESEVRRIARIGFESARKRNKKLCSVDKANVLETSQFWRDLVI 207 Query: 356 AIASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSA 535 ++ ++PDVELSHMYVDNAAMQLVRNP+QFD IVT N+FGDILSDEA+M+TGSIGMLPSA Sbjct: 208 EVSRDYPDVELSHMYVDNAAMQLVRNPRQFDVIVTGNLFGDILSDEAAMLTGSIGMLPSA 267 Query: 536 SV 541 S+ Sbjct: 268 SL 269
>LEU3_BORBR (Q7WKH4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 231 bits (590), Expect = 8e-61 Identities = 115/182 (63%), Positives = 141/182 (77%), Gaps = 4/182 (2%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTN 187 +L +R LG+FANLRPA + P+L AS+LK E+ G+DI+++RELTG IYFG PRG T Sbjct: 88 ILGLRKALGLFANLRPAILYPELASASSLKPEIVSGLDILIIRELTGDIYFGTPRGVRTA 147 Query: 188 DKG----EETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVT 355 G E G++T Y+ +E+ RIAR+ FE ARKR KLCSVDKANVLE S WR V Sbjct: 148 ADGAFAGEREGYDTMRYAESEVRRIARIGFESARKRNKKLCSVDKANVLETSQFWRDLVI 207 Query: 356 AIASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSA 535 ++ ++PDVELSHMYVDNAAMQLVRNP+QFD IVT N+FGDILSDEA+M+TGSIGMLPSA Sbjct: 208 EVSRDYPDVELSHMYVDNAAMQLVRNPRQFDVIVTGNLFGDILSDEAAMLTGSIGMLPSA 267 Query: 536 SV 541 S+ Sbjct: 268 SL 269
>LEU31_DECAR (Q47HR1) 3-isopropylmalate dehydrogenase 1 (EC 1.1.1.85) (Beta-IPM| dehydrogenase 1) (IMDH 1) (3-IPM-DH 1) Length = 350 Score = 231 bits (588), Expect = 1e-60 Identities = 116/179 (64%), Positives = 141/179 (78%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL IR L +FANLRPA + P+L +ASTLK EV G+DI+++RELTG IYFG+PRG Sbjct: 85 GLLGIRKDLNLFANLRPAILYPELANASTLKPEVVAGLDILIIRELTGDIYFGQPRGV-R 143 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + GE GFNT +YS +EI RI VAF+ A+KR +LCSVDK NVLE + LWR + I+ Sbjct: 144 EENGERVGFNTMVYSESEIRRIGHVAFQAAQKRDKRLCSVDKMNVLECTQLWRDVMIEIS 203 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 ++PDVELSHM VDNAAMQLV+ PKQFD +VT N+FGDILSDEASM+TGSIGMLPSAS+ Sbjct: 204 RDYPDVELSHMLVDNAAMQLVKAPKQFDVMVTGNMFGDILSDEASMLTGSIGMLPSASL 262
>LEU3_PROMA (Q7VC80) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 230 bits (587), Expect = 2e-60 Identities = 109/181 (60%), Positives = 145/181 (80%) Frame = +2 Query: 2 TGLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFG 181 TGLLN+RAGL +FAN+RP + L+ +S+LK E+ + VD++VVRELTGGIYFG+P+G Sbjct: 91 TGLLNLRAGLNLFANIRPIKIRQALISSSSLKSEIIKDVDLVVVRELTGGIYFGQPKGRI 150 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI 361 + ++ E FNT YS EIDRIA++AF+++ R K+CS+DKANVLE S LWR+RV Sbjct: 151 STEEAGERAFNTMTYSDYEIDRIAKIAFDLSETRRKKICSIDKANVLEVSQLWRERVIKA 210 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 ++P++EL+H YVDNAAMQLVR P QFD I+T+N+FGDI+SDEA+M+TGSIGMLPSAS+ Sbjct: 211 QEQYPNIELTHQYVDNAAMQLVREPAQFDVILTSNLFGDIISDEAAMLTGSIGMLPSASL 270 Query: 542 G 544 G Sbjct: 271 G 271
>LEU3_THIFE (Q56268) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 229 bits (585), Expect = 3e-60 Identities = 116/180 (64%), Positives = 140/180 (77%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL +R GL ++ANLRPA + PQL+DAS L+ E+ VDI+VVRELTG IYFG+PRG Sbjct: 90 GLLRLRKGLDLYANLRPAQIFPQLLDASPLRPELVRDVDILVVRELTGDIYFGQPRGLEV 149 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 D G+ GFNT +Y EI RIA VAF A+ R +LCSVDKANVLE + LWR+ VT +A Sbjct: 150 ID-GKRRGFNTMVYDEDEIRRIAHVAFRAAQGRRKQLCSVDKANVLETTRLWREVVTEVA 208 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASVG 544 ++PDV LSHMYVDNAAMQL+R P QFD ++T N+FGDILSDEAS +TGSIGMLPSAS+G Sbjct: 209 RDYPDVRLSHMYVDNAAMQLIRAPAQFDVLLTGNMFGDILSDEASQLTGSIGMLPSASLG 268
>LEU3_BORPE (Q7VY73) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 228 bits (580), Expect = 1e-59 Identities = 114/182 (62%), Positives = 140/182 (76%), Gaps = 4/182 (2%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTN 187 +L +R LG+FANLRPA + P+L AS+LK E+ G+DI+++RELTG IYFG PRG T Sbjct: 88 ILGLRKALGLFANLRPAILYPELASASSLKPEIVSGLDILIIRELTGDIYFGTPRGVRTA 147 Query: 188 DKG----EETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVT 355 G E G++T Y+ +E+ RIAR+ FE ARKR KLCSVDKANVLE S WR V Sbjct: 148 ADGAFAGEREGYDTMRYAESEVRRIARIGFESARKRNKKLCSVDKANVLETSQFWRDLVI 207 Query: 356 AIASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSA 535 ++ ++ DVELSHMYVDNAAMQLVRNP+QFD IVT N+FGDILSDEA+M+TGSIGMLPSA Sbjct: 208 EVSRDYLDVELSHMYVDNAAMQLVRNPRQFDVIVTGNLFGDILSDEAAMLTGSIGMLPSA 267 Query: 536 SV 541 S+ Sbjct: 268 SL 269
>LEU3_DESVH (Q726X1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 228 bits (580), Expect = 1e-59 Identities = 118/181 (65%), Positives = 141/181 (77%), Gaps = 1/181 (0%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAE-GVDIMVVRELTGGIYFGKPRGFG 181 GLL IR LG+FANLRPA + P+L A L+ ++A G+D++VVRELTG +YFG+P G Sbjct: 91 GLLGIRKALGLFANLRPAALFPELAGACLLRADIAAAGLDLVVVRELTGDVYFGQPAGIE 150 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI 361 T D G TGFNT IY E+ RIARVAF+ AR R ++CSVDKANVL S LWR+ V + Sbjct: 151 TRD-GLRTGFNTMIYDEDEVRRIARVAFDTARARKRRVCSVDKANVLATSRLWREVVEEV 209 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 A ++PDVELSHMYVDNAAMQLVR P QFD IVT N+FGDILSDEA++ITGSIGMLPSAS+ Sbjct: 210 ARDYPDVELSHMYVDNAAMQLVRWPAQFDVIVTGNLFGDILSDEAAVITGSIGMLPSASM 269 Query: 542 G 544 G Sbjct: 270 G 270
>LEU3_PSYAR (Q4FRV0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 367 Score = 225 bits (573), Expect = 7e-59 Identities = 110/186 (59%), Positives = 148/186 (79%), Gaps = 7/186 (3%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL IR+ LG+FANLR A + PQLV+AS++K E+ G+D+++VRELTGGIYFG+PRG T Sbjct: 90 GLLKIRSELGLFANLRVAKLYPQLVNASSIKPEIISGLDLLIVRELTGGIYFGEPRGIRT 149 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRG------GKLCSVDKANVLEASMLWRK 346 + GE+ G+NT +YS +EI+RI +VAFE+A+ R K+CS+DKANVLE + LW++ Sbjct: 150 LENGEQQGYNTMVYSTSEINRIGKVAFELAQTRAQAAGTPAKVCSIDKANVLEVTELWKQ 209 Query: 347 RVTAI-ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGM 523 + + +E+ DV LSHMY DNA MQL+++PKQFD +VT N+FGDILSDEA+M+TGSIGM Sbjct: 210 TMIELQQAEYSDVALSHMYADNACMQLIKDPKQFDVMVTGNLFGDILSDEAAMLTGSIGM 269 Query: 524 LPSASV 541 LPSAS+ Sbjct: 270 LPSASL 275
>LEU3_GEOSL (Q748X2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 224 bits (570), Expect = 2e-58 Identities = 114/179 (63%), Positives = 142/179 (79%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREV-AEGVDIMVVRELTGGIYFGKPRGFGT 184 LL +R G++ANLRPA + P L AS+LK EV A G +++V+RELTGGIYF +P+G Sbjct: 95 LLPLRKIFGLYANLRPAIIFPSLTGASSLKEEVIAGGFNVLVIRELTGGIYFAQPKGIEG 154 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + + GF+T YSV EI+RI VAF+ ARKRG K+CS+DKANVL +S+LWR+ VT IA Sbjct: 155 EGR-DRVGFDTMRYSVPEIERITHVAFQAARKRGKKVCSIDKANVLSSSVLWREVVTGIA 213 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 E+PDVELSHMYVDNAAMQLVR PKQFD I+ N+FGDILSDEA+M+TGS+GMLPSAS+ Sbjct: 214 KEYPDVELSHMYVDNAAMQLVRWPKQFDVILCENMFGDILSDEAAMLTGSLGMLPSASL 272
>LEU3_GLUOX (Q5FUG5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 369 Score = 223 bits (567), Expect = 4e-58 Identities = 107/180 (59%), Positives = 140/180 (77%), Gaps = 1/180 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTN 187 +L +R L +FANLRPA + L+DAS LK EV G+D+M+VRE GGIYFG+PRG T Sbjct: 94 ILKLRKELELFANLRPAKLFDALIDASALKPEVVRGLDLMIVRETVGGIYFGEPRGIETL 153 Query: 188 DKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI-A 364 G G NTE+Y+ +EI+R+ARVAF++ARKR ++CSV+K NV+E+ +LW++ VT + Sbjct: 154 PDGSRRGINTEVYTTSEIERVARVAFDLARKRDNRVCSVEKCNVMESGLLWKEVVTDVHK 213 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASVG 544 E+PDV+LSHM DN AMQLVR+P QFD IVT N+FGDILSD ASM+TGS+GMLPSA++G Sbjct: 214 REYPDVQLSHMLADNCAMQLVRDPNQFDVIVTGNLFGDILSDLASMLTGSLGMLPSATLG 273
>LEU3_PROMT (Q46LE2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 359 Score = 222 bits (565), Expect = 6e-58 Identities = 106/180 (58%), Positives = 142/180 (78%) Frame = +2 Query: 2 TGLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFG 181 TGLLN+R+ L +FAN+RP ++P L AS+LK + + VD++VVRELT GIYFG+P+G Sbjct: 91 TGLLNLRSSLDLFANIRPVKIIPSLTKASSLKEDFVKEVDLVVVRELTSGIYFGEPKGRI 150 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI 361 DKGE FNT Y+ E++RIA +AF++A++R K+CSVDKANVL+ S LWR+ + Sbjct: 151 KTDKGERA-FNTMTYTSEEVNRIAEIAFKLAKQRNQKVCSVDKANVLDVSQLWREETILV 209 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 ++++ D+EL+H YVDNAAMQLVRNP QFD I+T N+FGDILSD A+M+TGSIGMLPSAS+ Sbjct: 210 SNKYKDIELTHQYVDNAAMQLVRNPSQFDVILTGNLFGDILSDIAAMLTGSIGMLPSASL 269
>LEU3_PELUB (Q4FP17) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 368 Score = 221 bits (562), Expect = 1e-57 Identities = 108/180 (60%), Positives = 140/180 (77%), Gaps = 1/180 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTN 187 LL +R L +FANLRPA QLVDASTLK E+ G+DIM+VRELTGGIYFG+PRG Sbjct: 96 LLKLRKELKLFANLRPAICFEQLVDASTLKPEIVSGLDIMIVRELTGGIYFGEPRGIKPI 155 Query: 188 DKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI-A 364 + GE G NT Y+ +EI R+A+VAF++ARKR ++ S +K+NV+EA LW++ V + Sbjct: 156 ENGERKGINTHSYTTSEIVRVAKVAFDLARKRSNRVTSCEKSNVMEAGQLWKEEVQELHD 215 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASVG 544 E+ DVELSHM DN AMQL++NPKQFD IVT+N+FGD+LSD+ASM+TGS+G+LPSAS+G Sbjct: 216 KEYKDVELSHMLADNCAMQLLKNPKQFDVIVTDNLFGDMLSDQASMLTGSLGLLPSASLG 275
>LEU3_SILPO (Q5LWZ5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 367 Score = 220 bits (560), Expect = 2e-57 Identities = 105/180 (58%), Positives = 142/180 (78%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL +R + +F+NLRPA L D S+LK+++ G+DIM+VRELT G+YFG+PRG Sbjct: 92 GLLRLRKEMDLFSNLRPAQCFDALADFSSLKKDIVAGLDIMIVRELTSGVYFGEPRGI-F 150 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + E G NT+ Y+ +EI+R+AR AFE+A +R KLCS++KANV+E+ +LWR+ VT +A Sbjct: 151 EEGNERVGINTQRYTESEIERVARSAFELAMRRSKKLCSMEKANVMESGILWREVVTRVA 210 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASVG 544 ++P+VELSHMY DN AMQLVR PKQFD I+T+N+FGDILSD A+M+TGS+GMLPSAS+G Sbjct: 211 KDYPEVELSHMYADNGAMQLVRAPKQFDVILTDNLFGDILSDCAAMLTGSLGMLPSASLG 270
>LEU32_DECAR (Q479H7) 3-isopropylmalate dehydrogenase 2 (EC 1.1.1.85) (Beta-IPM| dehydrogenase 2) (IMDH 2) (3-IPM-DH 2) Length = 358 Score = 219 bits (559), Expect = 3e-57 Identities = 113/179 (63%), Positives = 136/179 (75%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL IR LG+ ANLRP V P+L +ASTL+ EV G+D+M+VRELTG IYFG+PRG T Sbjct: 89 GLLGIRKYLGLNANLRPIKVYPELANASTLRPEVVSGLDMMIVRELTGDIYFGQPRGIRT 148 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + E G+NT YS +EI IA +AF +AR+R GK+ SVDK NVLE LWR VT + Sbjct: 149 SGF-ERVGYNTMEYSESEIALIAEMAFRIARQRSGKVMSVDKMNVLECMQLWRDVVTKVG 207 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 FPDV L HM VDNAAMQLV+NPKQFD ++T N+FGDILSDEA+M+TGSIGMLPSAS+ Sbjct: 208 ERFPDVTLDHMLVDNAAMQLVKNPKQFDVLLTGNMFGDILSDEAAMLTGSIGMLPSASL 266
>LEU3_CHLTE (P59028) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 352 Score = 218 bits (554), Expect = 1e-56 Identities = 113/180 (62%), Positives = 137/180 (76%), Gaps = 1/180 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTN 187 LL IR LG+FANLRPA V LV +STLK EV +G D MV RELTGGIYFG+PRG+ Sbjct: 92 LLKIRKELGLFANLRPARVYDALVASSTLKTEVVQGTDFMVFRELTGGIYFGQPRGYD-- 149 Query: 188 DKGEETGFNTEIYSVAEIDRIARVAFEVARKRGG-KLCSVDKANVLEASMLWRKRVTAIA 364 E G+NT +Y E++RIAR+AFE A+KRG K+ S+DKANVLE S WR V + Sbjct: 150 ---ETRGWNTMVYERYEVERIARLAFEYAQKRGNAKVTSIDKANVLEVSQFWRNIVHEVH 206 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASVG 544 +FP++EL MYVDNAAMQ+VRNPKQF+ IVT+N+FGDILSD + MITGS+GMLPSAS+G Sbjct: 207 QDFPEIELVDMYVDNAAMQVVRNPKQFEVIVTSNLFGDILSDISGMITGSLGMLPSASIG 266
>LEU3_PELCD (Q3A3B2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 365 Score = 218 bits (554), Expect = 1e-56 Identities = 112/179 (62%), Positives = 140/179 (78%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREV-AEGVDIMVVRELTGGIYFGKPRGFGT 184 LL +R G+F NLRPA V P L AS+LK EV A G DI+VVRELTGGIYF +P+G Sbjct: 95 LLPLRRIFGLFCNLRPAIVFPALTSASSLKEEVIAGGFDILVVRELTGGIYFAQPKGV-E 153 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + GE GF+T Y+ AE++RI RVAF+ ARKRG KL S+DKANVL S+LWR+ V ++ Sbjct: 154 GEGGERRGFDTMAYTDAEVERITRVAFDAARKRGKKLVSIDKANVLSTSVLWREVVERVS 213 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 +++PDV LSHMYVDNAAMQLV+ PKQFD ++ N+FGDILSDEA+M+TGS+GMLPSAS+ Sbjct: 214 ADYPDVVLSHMYVDNAAMQLVKAPKQFDVLLCPNMFGDILSDEAAMLTGSLGMLPSASL 272
>LEU3_ZYMMO (Q5NPQ9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 349 Score = 216 bits (551), Expect = 3e-56 Identities = 108/178 (60%), Positives = 129/178 (72%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTN 187 +L +R L +FANLRPA + P+L S LK + G D+M+VRELTG +YFG PRG + Sbjct: 87 ILGLRKELDLFANLRPARLFPELQAESPLKENIVTGTDLMIVRELTGDVYFGTPRGQRKD 146 Query: 188 DKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIAS 367 D+ GF+T Y+ E+ RIAR+ FE AR R G LCS+DK+NVLE S LWR V IA Sbjct: 147 DQNRREGFDTMRYNEDEVKRIARIGFETARSRSGNLCSIDKSNVLETSQLWRTVVLEIAQ 206 Query: 368 EFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 E+PDVELSHMYVDNAAMQLVR P QFD IVT N+FGDILSD AS GSIG+LPSAS+ Sbjct: 207 EYPDVELSHMYVDNAAMQLVRAPDQFDVIVTGNLFGDILSDLASACVGSIGLLPSASL 264
>LEU3_RALEJ (Q46YW0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 355 Score = 214 bits (546), Expect = 1e-55 Identities = 112/182 (61%), Positives = 133/182 (73%), Gaps = 4/182 (2%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTN 187 +L +R L +FAN RPA P+L AS+LK E+ G+DI++VREL G IYFG+PRG Sbjct: 86 ILGLRKHLQLFANFRPAICYPELTGASSLKPELVAGLDILIVRELNGDIYFGQPRGVREA 145 Query: 188 D----KGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVT 355 KG GF+T YS EI RIA VAF+ A KRG KLCSVDKANVLE W+ V Sbjct: 146 PDGLFKGAREGFDTMRYSEPEIRRIAHVAFQAAAKRGKKLCSVDKANVLETFQFWKDIVI 205 Query: 356 AIASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSA 535 ++ E+PDVELSHMYVDNAAMQLV+ PK FD IVT N+FGDILSDEA+M+TGSIGMLPSA Sbjct: 206 DVSKEYPDVELSHMYVDNAAMQLVKAPKSFDVIVTGNMFGDILSDEAAMLTGSIGMLPSA 265 Query: 536 SV 541 S+ Sbjct: 266 SL 267
>LEU3_BACLD (Q65GI9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 214 bits (546), Expect = 1e-55 Identities = 110/179 (61%), Positives = 131/179 (73%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL IR L +FANLRP V L AS LK E EGVD ++VRELTGG+YFGKP Sbjct: 91 GLLAIRKQLDLFANLRPVKVFESLAGASPLKTEYIEGVDFVIVRELTGGLYFGKPSEQYV 150 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 N GEE +T Y +E++R+ R AF++A+ R GK+ SVDKANVLE+S LWRK +A Sbjct: 151 NQNGEEEAVDTLFYKKSEMERVIREAFQMAQSRKGKVTSVDKANVLESSKLWRKTAEEVA 210 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 EFPDV+L HM VDNAAMQL+ P QFD IVT N+FGDILSDEASM+TGS+GMLPSAS+ Sbjct: 211 KEFPDVKLEHMLVDNAAMQLIYAPGQFDIIVTENMFGDILSDEASMLTGSLGMLPSASL 269
>LEU3_THETN (Q8RDK0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 355 Score = 214 bits (544), Expect = 2e-55 Identities = 114/180 (63%), Positives = 138/180 (76%), Gaps = 1/180 (0%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAE-GVDIMVVRELTGGIYFGKPRGFG 181 GLL +R LGV+ANLRPA + P L DAS LK E+ E G+DI+VVRELTGGIYFG PRG Sbjct: 90 GLLALRKSLGVYANLRPAVLYPSLKDASPLKNELLEKGLDILVVRELTGGIYFG-PRGKE 148 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI 361 G ++TE+Y EI+RIA +AFE A +R K+ SVDKANVLE+S LWRK V + Sbjct: 149 AIGYGFRA-YDTEVYETQEIERIAVIAFEAALRRRKKITSVDKANVLESSRLWRKTVEEV 207 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 A +P+VEL+HMYVDN AMQLV+NP QFD I+TNN+FGDILSDEA+ I GSIG+LPSAS+ Sbjct: 208 AKRYPEVELNHMYVDNCAMQLVKNPFQFDVILTNNMFGDILSDEAAQIVGSIGILPSASL 267
>LEU3_RALSO (Q8XXX5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 356 Score = 214 bits (544), Expect = 2e-55 Identities = 110/182 (60%), Positives = 133/182 (73%), Gaps = 4/182 (2%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTN 187 +L +R L +FAN RPA P+L AS++K E+ G+DI++VRELTG IYFG+PRG Sbjct: 87 ILGLRKHLQLFANFRPAICYPELAGASSMKPEIVAGLDILIVRELTGDIYFGQPRGVRAA 146 Query: 188 DKG----EETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVT 355 G GF+T YS EI RIA VAF+ A KRG KLCSVDKANVLE W+ VT Sbjct: 147 PDGLFAGAREGFDTMRYSEPEIRRIAHVAFQAAAKRGKKLCSVDKANVLETFQFWKDIVT 206 Query: 356 AIASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSA 535 + E+P+VELSHMYVDNAAMQLV+ PK FD +VT N+FGDILSDEA+M+TGSIGMLPSA Sbjct: 207 DVHKEYPEVELSHMYVDNAAMQLVKAPKNFDVVVTGNMFGDILSDEAAMLTGSIGMLPSA 266 Query: 536 SV 541 S+ Sbjct: 267 SL 268
>LEU3_BURCE (Q845W3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 355 Score = 213 bits (543), Expect = 2e-55 Identities = 112/182 (61%), Positives = 133/182 (73%), Gaps = 4/182 (2%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTN 187 +L +R L +FAN RPA PQLVDAS LK E+ G+DI++VREL G IYFG+PRG Sbjct: 86 ILGLRKHLELFANFRPAICYPQLVDASPLKPELVAGLDILIVRELNGDIYFGQPRGVRAA 145 Query: 188 DKG----EETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVT 355 G E GF+T YS E+ RIA VAF+ A+KR KL SVDK+NVLE S WR + Sbjct: 146 PDGPFAGEREGFDTMRYSEPEVRRIAHVAFQAAQKRAKKLLSVDKSNVLETSQFWRDIMI 205 Query: 356 AIASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSA 535 ++ E+ DVELSHMYVDNAAMQL + PKQFD IVT N+FGDILSDEASM+TGSIGMLPSA Sbjct: 206 DVSKEYADVELSHMYVDNAAMQLAKAPKQFDVIVTGNMFGDILSDEASMLTGSIGMLPSA 265 Query: 536 SV 541 S+ Sbjct: 266 SL 267
>LEU3_CAUCR (Q9ABN3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 350 Score = 213 bits (543), Expect = 2e-55 Identities = 103/181 (56%), Positives = 140/181 (77%), Gaps = 1/181 (0%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLLN+R + VFANLRPA L AS+LK E+ G+DIM VREL GG+YFG+PRG Sbjct: 86 GLLNLRKAMDVFANLRPAYCFEALAGASSLKPELVSGLDIMFVRELVGGVYFGQPRGIED 145 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI- 361 G++ GF+T++Y+ +EI+R+ RVAFE+AR R K+ S +K+NV+E+ +LW++ +T + Sbjct: 146 LADGQKKGFDTQVYTTSEIERVGRVAFELARGRTNKVHSAEKSNVMESGLLWKQVITELH 205 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 A E+PDV+L H+ DN AMQLVR PKQFD IVT+N+FGDILSD A+M+TGS+GMLPSA++ Sbjct: 206 AREYPDVQLEHILADNCAMQLVRAPKQFDVIVTDNLFGDILSDAAAMLTGSLGMLPSAAL 265 Query: 542 G 544 G Sbjct: 266 G 266
>LEU3_CLOAB (Q97EE2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 213 bits (543), Expect = 2e-55 Identities = 113/179 (63%), Positives = 142/179 (79%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVA-EGVDIMVVRELTGGIYFGKPRGFGT 184 L+ +R GLG++ANLRPA V L AS LK E+ +GVD++VVRELTGGIYFG+ RG Sbjct: 93 LMGLRGGLGLYANLRPAKVYDILKSASPLKEEIINKGVDLLVVRELTGGIYFGE-RGRDI 151 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + G + ++TE Y+V EI RIA VAF+ A KR K+ SVDKAN+LE+S LWR+ VT +A Sbjct: 152 QN-GINSAYDTERYNVEEIKRIAHVAFKAALKRNKKVTSVDKANILESSRLWRETVTEVA 210 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 E+P+VEL+++YVDNAAMQLVR P QFD IVT+NIFGDIL+DEASM+TGSIGMLPSAS+ Sbjct: 211 KEYPEVELNYLYVDNAAMQLVREPSQFDVIVTSNIFGDILTDEASMVTGSIGMLPSASL 269
>LEU3_BACHD (Q9K8E9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 213 bits (541), Expect = 4e-55 Identities = 108/179 (60%), Positives = 135/179 (75%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL +R GL +FANLRP TV L DASTLK +V +GVD+++VRELTGG+YFG+PR Sbjct: 91 GLLGLRKGLNLFANLRPVTVYDSLADASTLKNDVIDGVDLLIVRELTGGLYFGEPRERRG 150 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + EE +T +Y+ E+ RI R AFE+A R + SVDKANVLE+S +WR+ +A Sbjct: 151 EGETEEV-VDTLLYTRGEMRRIIRKAFELAMVRNKHVTSVDKANVLESSRMWREVANEVA 209 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 EFP+V L HM VDNAAMQL+R PKQFD +VT N+FGDILSDEASM+TGS+GMLPSAS+ Sbjct: 210 QEFPEVTLEHMLVDNAAMQLIRRPKQFDVLVTENLFGDILSDEASMVTGSLGMLPSASL 268
>LEU3_BURPS (Q63JL2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 355 Score = 213 bits (541), Expect = 4e-55 Identities = 112/182 (61%), Positives = 132/182 (72%), Gaps = 4/182 (2%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTN 187 +L +R L +FAN RPA PQLVDAS LK E+ G+DI++VREL G IYFG+PRG Sbjct: 86 ILGLRKHLELFANFRPAICYPQLVDASPLKPELVAGLDILIVRELNGDIYFGQPRGVRAA 145 Query: 188 DKGE----ETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVT 355 G GF+T YS E+ RIA VAF+ ARKR KL SVDK+NVLE S WR + Sbjct: 146 PDGPFAGAREGFDTMRYSEPEVRRIAHVAFQAARKRAKKLLSVDKSNVLETSQFWRDVMI 205 Query: 356 AIASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSA 535 ++ E+ DVELSHMYVDNAAMQL + PKQFD IVT N+FGDILSDEASM+TGSIGMLPSA Sbjct: 206 DVSKEYADVELSHMYVDNAAMQLAKAPKQFDVIVTGNMFGDILSDEASMLTGSIGMLPSA 265 Query: 536 SV 541 S+ Sbjct: 266 SL 267
>LEU3_BURMA (Q62AI9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 355 Score = 213 bits (541), Expect = 4e-55 Identities = 112/182 (61%), Positives = 132/182 (72%), Gaps = 4/182 (2%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTN 187 +L +R L +FAN RPA PQLVDAS LK E+ G+DI++VREL G IYFG+PRG Sbjct: 86 ILGLRKHLELFANFRPAICYPQLVDASPLKPELVAGLDILIVRELNGDIYFGQPRGVRAA 145 Query: 188 DKGE----ETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVT 355 G GF+T YS E+ RIA VAF+ ARKR KL SVDK+NVLE S WR + Sbjct: 146 PDGPFAGAREGFDTMRYSEPEVRRIAHVAFQAARKRAKKLLSVDKSNVLETSQFWRDVMI 205 Query: 356 AIASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSA 535 ++ E+ DVELSHMYVDNAAMQL + PKQFD IVT N+FGDILSDEASM+TGSIGMLPSA Sbjct: 206 DVSKEYADVELSHMYVDNAAMQLAKAPKQFDVIVTGNMFGDILSDEASMLTGSIGMLPSA 265 Query: 536 SV 541 S+ Sbjct: 266 SL 267
>LEU3_AZOVI (P96197) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 360 Score = 212 bits (540), Expect = 5e-55 Identities = 108/163 (66%), Positives = 128/163 (78%) Frame = +2 Query: 53 PATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTNDKGEETGFNTEIYSV 232 P + PQL +ASTL+ EV G+DI++VRELTGGIYFG PR GE ++T YS Sbjct: 106 PGVLYPQLAEASTLRPEVVAGLDILIVRELTGGIYFGAPRESRLLANGERMAYDTLPYSE 165 Query: 233 AEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIASEFPDVELSHMYVDNA 412 +EI RIA+V F++AR RG KLCSVDKANVL +S LWR V +A ++PDV LSHMYVDNA Sbjct: 166 SEIRRIAKVGFDMARVRGKKLCSVDKANVLASSQLWRAVVEEVAKDYPDVVLSHMYVDNA 225 Query: 413 AMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 AMQLVR PKQFD IVT+N+FGDILSDEASM+TGSIGMLPSAS+ Sbjct: 226 AMQLVRAPKQFDVIVTDNMFGDILSDEASMLTGSIGMLPSASL 268
>LEU3_CLOPA (P31958) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 212 bits (540), Expect = 5e-55 Identities = 115/180 (63%), Positives = 136/180 (75%), Gaps = 2/180 (1%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVA-EGVDIMVVRELTGGIYFGKPRGFGT 184 LL +R LG++ANLRPA V L AS LK E+ EGVD++VVREL GGIYFG GT Sbjct: 93 LLGLRGALGLYANLRPAKVYNVLKSASPLKNEIIDEGVDLLVVRELIGGIYFGDR---GT 149 Query: 185 ND-KGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI 361 + G ET F+TE Y+V E+ RIA AF+ A KR K+ SVDKANVL+AS LWRK V + Sbjct: 150 KEVNGVETAFDTEKYNVDEVKRIAHSAFKAAMKRRKKVTSVDKANVLDASRLWRKTVNEV 209 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 + E+P+VELSH+YVDN AMQLVR P QFD I+TNNIFGDILSDEASMITGSIGML S+S+ Sbjct: 210 SKEYPEVELSHLYVDNTAMQLVRKPSQFDVILTNNIFGDILSDEASMITGSIGMLASSSI 269
>LEU3_BACSK (Q5WEN4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 364 Score = 211 bits (538), Expect = 8e-55 Identities = 109/179 (60%), Positives = 136/179 (75%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL IR LG++ANLRP VL L+ ASTLK EV VD+++VRELTGG+YFG+PR Sbjct: 91 GLLQIRKALGLYANLRPVRVLKPLMGASTLKEEVLADVDLLIVRELTGGLYFGEPRE-RR 149 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 GE+ +T +Y+ EI+RI AF+ AR R ++ SVDKANVLE+S LWR+ +A Sbjct: 150 QINGEDGAVDTLLYTRGEIERIVHQAFQFARTRKKRVVSVDKANVLESSRLWREIADEVA 209 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 E+PDV LSHM VDNAAMQL+R+P+QFD IVT N+FGDILSDEASMITGS+G+LPSAS+ Sbjct: 210 REYPDVTLSHMLVDNAAMQLIRDPRQFDVIVTENLFGDILSDEASMITGSLGLLPSASM 268
>LEU3_PROMP (Q7V1R9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 209 bits (531), Expect = 5e-54 Identities = 106/180 (58%), Positives = 139/180 (77%) Frame = +2 Query: 2 TGLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFG 181 +GLL +R L +FAN+RP + L+D+S+ K+EV E VD++VVREL GGIYFG+PRG Sbjct: 91 SGLLKLREALNLFANIRPVKIRKSLLDSSSFKKEVIENVDLIVVRELIGGIYFGQPRGEI 150 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI 361 T K ++ FNT +Y EI+RI VA ++A +R K+CSVDK+NVLE S LWR V+ + Sbjct: 151 TQTKIKKA-FNTMVYDSNEIERITEVAIKIANQRSKKICSVDKSNVLEVSQLWRDTVSLV 209 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 AS+ D+ LS+MYVDNAAMQLV++P QFD I+T+N+FGDILSD A+MITGSIGMLPSAS+ Sbjct: 210 ASKENDLALSNMYVDNAAMQLVKDPGQFDVILTSNLFGDILSDLAAMITGSIGMLPSASL 269
>LEU3_THETH (P61495) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 345 Score = 208 bits (530), Expect = 7e-54 Identities = 107/181 (59%), Positives = 130/181 (71%) Frame = +2 Query: 2 TGLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFG 181 TGLL++R +FANLRPA V P L S LK E+A GVD+++VRELTGGIYFG+PRG Sbjct: 88 TGLLSLRKSQDLFANLRPAKVFPGLERLSPLKEEIARGVDVLIVRELTGGIYFGEPRGMS 147 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI 361 E +NTE YS E++R+ARVAFE ARKR + SVDKANVLE WRK V + Sbjct: 148 -----EAEAWNTERYSKPEVERVARVAFEAARKRRKHVVSVDKANVLEVGEFWRKTVEEV 202 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 +PDV L H YVD AAM LVR+P +FD +VT NIFGDILSD AS++ GS+G+LPSAS+ Sbjct: 203 GRGYPDVALEHQYVDAAAMHLVRSPARFDVVVTGNIFGDILSDLASVLPGSLGLLPSASL 262 Query: 542 G 544 G Sbjct: 263 G 263
>LEU3_SYMTH (Q67JY2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 368 Score = 207 bits (526), Expect = 2e-53 Identities = 105/181 (58%), Positives = 131/181 (72%), Gaps = 1/181 (0%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREV-AEGVDIMVVRELTGGIYFGKPRGFG 181 GLL IR ++ANLRP + P L DAS LK E+ GVD ++VREL GGIYFG+PRG Sbjct: 94 GLLAIRKRYDLYANLRPILLYPPLKDASPLKNEIIGGGVDFIIVRELVGGIYFGEPRGIE 153 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI 361 T G G NTE+Y+ AEI RIAR+ FE+AR R +L SVDK NV+EA LWR V + Sbjct: 154 TLPDGTRRGVNTEVYTDAEIARIARMGFEIARGRRRRLTSVDKGNVMEAGKLWRTVVDEV 213 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 A EFPDVE+ H+ DNAAMQ++R P FD ++ +N+FGD LSDEA+M+TGSIG+LPSAS+ Sbjct: 214 AREFPDVEVEHLLADNAAMQILRRPGDFDVMLASNLFGDFLSDEAAMLTGSIGLLPSASL 273 Query: 542 G 544 G Sbjct: 274 G 274
>LEU3_THET8 (Q5SIY4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 345 Score = 206 bits (525), Expect = 3e-53 Identities = 106/181 (58%), Positives = 129/181 (71%) Frame = +2 Query: 2 TGLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFG 181 TGLL++R +FANLRPA V P L S LK E+A GVD+++VRELTGGIYFG+PRG Sbjct: 88 TGLLSLRKSQDLFANLRPAKVFPGLERLSPLKEEIARGVDVLIVRELTGGIYFGEPRGMS 147 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI 361 E +NTE YS E++R+ARVAFE ARKR + SVDKANVLE WRK V + Sbjct: 148 -----EAEAWNTERYSKPEVERVARVAFEAARKRRKHVVSVDKANVLEVGEFWRKTVEEV 202 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 +PDV L H YVD AM LVR+P +FD +VT NIFGDILSD AS++ GS+G+LPSAS+ Sbjct: 203 GRGYPDVALEHQYVDAMAMHLVRSPARFDVVVTGNIFGDILSDLASVLPGSLGLLPSASL 262 Query: 542 G 544 G Sbjct: 263 G 263
>LEU3_THET2 (P61494) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 345 Score = 206 bits (525), Expect = 3e-53 Identities = 106/181 (58%), Positives = 129/181 (71%) Frame = +2 Query: 2 TGLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFG 181 TGLL++R +FANLRPA V P L S LK E+A GVD+++VRELTGGIYFG+PRG Sbjct: 88 TGLLSLRKSQDLFANLRPAKVFPGLERLSPLKEEIARGVDVLIVRELTGGIYFGEPRGMS 147 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI 361 E +NTE YS E++R+ARVAFE ARKR + SVDKANVLE WRK V + Sbjct: 148 -----EAEAWNTERYSKPEVERVARVAFEAARKRRKHVVSVDKANVLEVGEFWRKTVEEV 202 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 +PDV L H YVD AM LVR+P +FD +VT NIFGDILSD AS++ GS+G+LPSAS+ Sbjct: 203 GRGYPDVALEHQYVDAMAMHLVRSPARFDVVVTGNIFGDILSDLASVLPGSLGLLPSASL 262 Query: 542 G 544 G Sbjct: 263 G 263
>LEU3_BRAJA (Q89X19) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 206 bits (525), Expect = 3e-53 Identities = 100/181 (55%), Positives = 136/181 (75%), Gaps = 1/181 (0%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL +R LG+FANLRPA P L DAS+LKRE EG+DIM+VRELTGG+YFG+P+ Sbjct: 92 GLLRLRKDLGLFANLRPAVCYPALADASSLKREAVEGLDIMIVRELTGGVYFGEPKTITD 151 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI- 361 G++ +T++Y EI+RIARVAF++A+KR K+ S++K NV+++ +LW + VT + Sbjct: 152 LGNGQKRAIDTQVYDTYEIERIARVAFDLAKKRKNKVTSMEKRNVMKSGVLWNEVVTQVH 211 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 E+PDV L H D+ M LV+ PKQFD IVT+N+FGD+LSD A+M+TGS+GMLPSAS+ Sbjct: 212 KREYPDVTLEHQLADSGGMMLVKWPKQFDVIVTDNLFGDMLSDIAAMLTGSLGMLPSASL 271 Query: 542 G 544 G Sbjct: 272 G 272
>LEU3_AQUAE (O66607) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 364 Score = 206 bits (524), Expect = 3e-53 Identities = 106/180 (58%), Positives = 128/180 (71%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL IR L ++ANLRPA V L+ +S LK EV +G D++V+RELT GIY+G+PRG Sbjct: 92 GLLRIRKELDLYANLRPAKVWDALISSSPLKEEVVKGTDMIVIRELTSGIYYGEPRGI-F 150 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + G+ NT Y+ EI RI R FE+ARKR KL SVDKANVLE S LWR+ V Sbjct: 151 EENGKRYAINTMKYTEDEIRRIVRKGFEIARKRRKKLTSVDKANVLEVSALWRQIVEEEK 210 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASVG 544 +PDVEL H+Y+DN AMQLVR P FD IVT NIFGDILSDEA ++ GS+GMLPSAS+G Sbjct: 211 ENYPDVELEHLYIDNCAMQLVRRPTSFDVIVTGNIFGDILSDEAGVVVGSLGMLPSASIG 270
>LEU3_BACSU (P05645) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 365 Score = 206 bits (524), Expect = 3e-53 Identities = 104/179 (58%), Positives = 130/179 (72%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL+IR L +FANLRP V L D S LK+E + VD ++VRELTGG+YFG+P Sbjct: 91 GLLSIRKQLDLFANLRPVKVFESLSDRSPLKKEYIDNVDFVIVRELTGGLYFGQPSKRYV 150 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 N +GE+ +T Y EI+R+ R F++A R GK+ SVDKANVLE+S LWR+ +A Sbjct: 151 NTEGEQEAVDTLFYKRTEIERVIREGFKMAAARKGKVTSVDKANVLESSRLWREVAEDVA 210 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 EFPDV+L HM VDNAAMQL+ P QFD +VT N+FGDILSDEASM+TGS+GMLPSAS+ Sbjct: 211 QEFPDVKLEHMLVDNAAMQLIYAPNQFDVVVTENMFGDILSDEASMLTGSLGMLPSASL 269
>LEU3_GEOKA (Q5KWJ4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 371 Score = 205 bits (522), Expect = 6e-53 Identities = 107/179 (59%), Positives = 132/179 (73%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL IR L ++ANLRP LV AS LK ++ +GVD ++VRELTGGIYFG+P G Sbjct: 92 GLLAIRKQLDLYANLRPVVCYDSLVSASPLKPDLVQGVDFVIVRELTGGIYFGQPSG-RV 150 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + GEE +T +Y EI+RI R+AF +AR R K+ SVDKANVL +S LWR+ +A Sbjct: 151 VENGEEKAVDTLLYKKEEIERIVRMAFILARGRKKKVTSVDKANVLSSSRLWREVAEEVA 210 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 +FPDV L HM VDNAAMQL+R PKQFD IVT N+FGDILSDEASM++GS+GMLPSAS+ Sbjct: 211 KQFPDVTLEHMLVDNAAMQLIRAPKQFDVIVTENMFGDILSDEASMLSGSLGMLPSASL 269
>LEU3_RHOPA (Q6ND82) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 204 bits (519), Expect = 1e-52 Identities = 98/181 (54%), Positives = 136/181 (75%), Gaps = 1/181 (0%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL +R LG+FANLRPA P L D+S+LKR+V EG+DIM+VRELTGG+YFG+P+ Sbjct: 92 GLLRLRKDLGLFANLRPAVCYPALADSSSLKRDVVEGLDIMIVRELTGGVYFGEPKTITD 151 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 G++ +T++Y EI+RI RVAF++ARKR K+ S++K NV++ +LW + +TA+ Sbjct: 152 LGNGQKRAVDTQVYDTYEIERIGRVAFDLARKRRNKVTSMEKRNVMKTGVLWNEVITAVH 211 Query: 365 S-EFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 E+ DV+L H D+ M LV+ PKQFD IVT+N+FGD+LSD A+M+TGS+GMLPSAS+ Sbjct: 212 DREYKDVQLDHQLADSGGMNLVKWPKQFDVIVTDNLFGDMLSDIAAMLTGSLGMLPSASL 271 Query: 542 G 544 G Sbjct: 272 G 272
>LEU3_THEAQ (P24098) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 344 Score = 204 bits (519), Expect = 1e-52 Identities = 105/181 (58%), Positives = 128/181 (70%) Frame = +2 Query: 2 TGLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFG 181 +GLL +R +FANLRPA V P L S LK E+A GVD+++VRELTGGIYFG+PRG Sbjct: 88 SGLLALRKSQDLFANLRPAKVFPGLERLSPLKEEIARGVDVLIVRELTGGIYFGEPRGMS 147 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI 361 E +NTE YS E++R+A+VAFE ARKR L SVDKANVLE WRK V + Sbjct: 148 -----EAEAWNTERYSKPEVERVAKVAFEAARKRRRHLTSVDKANVLEVGEFWRKTVEEV 202 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 +PDV L H YVD AM LV+NP +FD +VT NIFGDILSD AS++ GS+G+LPSAS+ Sbjct: 203 HKGYPDVALDHQYVDAMAMHLVKNPARFDVVVTGNIFGDILSDLASVLPGSLGLLPSASL 262 Query: 542 G 544 G Sbjct: 263 G 263
>LEU3_BUCPS (P59027) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 204 bits (518), Expect = 2e-52 Identities = 103/179 (57%), Positives = 140/179 (78%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAE-GVDIMVVRELTGGIYFGKPRGFGT 184 LL IR +F+NLRPA + L S L+R+++E G DI+ VRELTGGIYFGKP+G+ Sbjct: 94 LLPIRKYFNLFSNLRPAKLYSTLNHLSPLRRDISEKGFDILCVRELTGGIYFGKPKGYIK 153 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 N ++ F+TEIY +EI RIA + F++A+ R K+ SVDKANVLE+S+LWR+ V I+ Sbjct: 154 NII-DKKAFDTEIYYASEIKRIAHIGFKLAQNRKYKITSVDKANVLESSVLWRETVNTIS 212 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 E+PDV+LSH+Y+D+AAMQ+++NP +FD I+T+N+FGDILSDE +MITGSIGMLPSAS+ Sbjct: 213 KEYPDVKLSHLYIDHAAMQIIKNPDKFDVILTSNLFGDILSDECAMITGSIGMLPSASL 271
>LEU3_AGRT5 (P24404) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 203 bits (516), Expect = 3e-52 Identities = 100/181 (55%), Positives = 136/181 (75%), Gaps = 1/181 (0%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL +R L +FANLRPA P L AS+LK E+ EG+DI++VRELTGG+YFG+P+ Sbjct: 92 GLLRLRKDLELFANLRPAICYPALAAASSLKPELVEGLDILIVRELTGGVYFGEPKQIID 151 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI- 361 G++ G +T+IY EI+RIA VAFE+AR R ++CS++K NV+++ +LW + VT Sbjct: 152 LGNGQKRGIDTQIYDTFEIERIASVAFELARSRDNRVCSMEKRNVMKSGVLWNQVVTETH 211 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 A+++ DV+L HM D MQLVR PKQFD IVT+N+FGD+LSD A+M+TGS+GMLPSAS+ Sbjct: 212 AAKYKDVQLEHMLADAGGMQLVRKPKQFDVIVTDNLFGDMLSDVAAMLTGSLGMLPSASL 271 Query: 542 G 544 G Sbjct: 272 G 272
>LEU3_VIBCH (Q9KP82) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 202 bits (515), Expect = 4e-52 Identities = 104/179 (58%), Positives = 136/179 (75%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREV-AEGVDIMVVRELTGGIYFGKPRGFGT 184 LL +R +F NLRPA + L S L+ ++ A G DI+VVRELTGGIYFG+P+G Sbjct: 96 LLPLRKHFQLFCNLRPAQIHQGLEAFSPLRADISARGFDIVVVRELTGGIYFGQPKG-RE 154 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + E F+TE+Y EI+RIAR+AFE AR R K+CS+DKANVL++S+LWR+ V+ IA Sbjct: 155 GEGAHEKAFDTEVYHRFEIERIARIAFESARLRRKKVCSIDKANVLQSSILWREVVSEIA 214 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 E+PDV LSHMY+DNA MQL+++P QFD ++ +NIFGDILSDE +MITGS+GMLPSAS+ Sbjct: 215 KEYPDVSLSHMYIDNATMQLIKDPAQFDVMLCSNIFGDILSDECAMITGSMGMLPSASM 273
>LEU3_RHIME (Q92KY8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 202 bits (513), Expect = 6e-52 Identities = 98/181 (54%), Positives = 136/181 (75%), Gaps = 1/181 (0%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL +R L +FANLRPA P L +AS+LK E+ EG+DI++VRELTGG+YFG+P+ Sbjct: 92 GLLRLRKDLELFANLRPAICYPALANASSLKPELVEGLDILIVRELTGGVYFGEPKEIVD 151 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI- 361 G++ G +T++Y EI+RIA VAFE+AR R ++CS++K NV+++ +LW + VT Sbjct: 152 LGNGQKRGIDTQVYDTYEIERIAGVAFELARTRNNRVCSMEKRNVMKSGVLWNQVVTETH 211 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 +++ DV+L HM D MQLVR PKQFD IVT+N+FGD+LSD A+M+TGS+GMLPSAS+ Sbjct: 212 KAKYSDVQLEHMLADAGGMQLVRQPKQFDVIVTDNLFGDMLSDVAAMLTGSLGMLPSASL 271 Query: 542 G 544 G Sbjct: 272 G 272
>LEU3_BUCAP (O85064) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 200 bits (509), Expect = 2e-51 Identities = 100/179 (55%), Positives = 135/179 (75%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVA-EGVDIMVVRELTGGIYFGKPRGFGT 184 LL +R +F+NLRPA + L + S L+ ++ +G DI+ +RELTGGIYFGKP+G Sbjct: 95 LLPLRKHFNLFSNLRPAKLRVDLKNLSPLRSDIVRDGFDILCIRELTGGIYFGKPKGRFK 154 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 N GE F+TEIY EI+RIA +AFE+A R K+CS+DKANVLE+S+LWR+ V ++ Sbjct: 155 NKNGEYA-FDTEIYYDFEIERIANLAFELASSRRCKVCSIDKANVLESSVLWREIVKKVS 213 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 +PDV LSH+Y+DNA MQ+++NP QFD ++ +NIFGDI+SDE +MITGSIGMLPSAS+ Sbjct: 214 KNYPDVHLSHLYIDNACMQIIKNPTQFDILLCSNIFGDIISDECAMITGSIGMLPSASL 272
>LEU3_NITWN (Q3SNU3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 200 bits (508), Expect = 2e-51 Identities = 99/181 (54%), Positives = 134/181 (74%), Gaps = 1/181 (0%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL +R L ++ANLRPA P L ++S+LK EV EG+DIM+VRELTGG+YFG+P+ Sbjct: 92 GLLRLRKDLALYANLRPAICYPALAESSSLKPEVVEGLDIMIVRELTGGVYFGEPKTVTD 151 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI- 361 G++ +T++Y EI+RIARVAF++ARKR KL S++K NV++ +LW + VT + Sbjct: 152 LGNGQKRAVDTQVYDTYEIERIARVAFDLARKRRNKLTSMEKRNVMKTGVLWHEVVTQVH 211 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 E+ DV L H D+ MQLVR PKQFD IVT+N+FGD+LSD A+M+TGS+GMLPSAS+ Sbjct: 212 QREYKDVALQHQLADSGGMQLVRWPKQFDVIVTDNLFGDMLSDIAAMLTGSLGMLPSASL 271 Query: 542 G 544 G Sbjct: 272 G 272
>LEU3_VIBPA (Q87SS8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 199 bits (507), Expect = 3e-51 Identities = 101/179 (56%), Positives = 136/179 (75%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVA-EGVDIMVVRELTGGIYFGKPRGFGT 184 LL +R +F NLRPA + L S L+ +++ G DI+VVRELTGGIYFG+P+G Sbjct: 96 LLPLRKHFQLFCNLRPAQIHAGLEAFSPLRADISGRGFDIVVVRELTGGIYFGQPKG-RE 154 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + E F+TE+Y EI+RIA++AFE AR R K+CS+DKANVL++S+LWR+ V IA Sbjct: 155 GEGANEKAFDTEVYHRYEIERIAKIAFESARLRRKKVCSIDKANVLQSSILWREVVEEIA 214 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 ++PDVELSHMY+DNA MQL+++P QFD ++ +NIFGDI+SDE +MITGS+GMLPSAS+ Sbjct: 215 KDYPDVELSHMYIDNATMQLIKDPAQFDVMLCSNIFGDIISDECAMITGSMGMLPSASL 273
>LEU3_COLP3 (Q47WG3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 199 bits (507), Expect = 3e-51 Identities = 100/179 (55%), Positives = 135/179 (75%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAE-GVDIMVVRELTGGIYFGKPRGFGT 184 LL +R+ +F N+RPAT+ P L STL+ +++E G D++V+RELTG IYFG+P+G Sbjct: 92 LLGLRSHFDLFCNMRPATLQPALSSLSTLRSDISEQGFDVLVIRELTGDIYFGEPKG-RR 150 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + EETGF++ YS E+ RI+ +AF+ A+KR K+ SVDKANVL S LWR+ V +A Sbjct: 151 GEGEEETGFDSMFYSRREVKRISHLAFQAAQKRNNKVTSVDKANVLATSQLWRQVVEEVA 210 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 E+PDVEL H+YVDNAAMQLVR+P QFD ++ N+FGDILSD +MITGS+G+LPSAS+ Sbjct: 211 VEYPDVELEHLYVDNAAMQLVRDPNQFDVMLCPNLFGDILSDICAMITGSMGLLPSASL 269
>LEU3_YERPS (Q66EM2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 199 bits (506), Expect = 4e-51 Identities = 102/180 (56%), Positives = 137/180 (76%), Gaps = 2/180 (1%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVA-EGVDIMVVRELTGGIYFGKPRGFGT 184 LL +R +F+NLRPA + L D L+ ++A G DI+ VRELTGGIYFG+P+G Sbjct: 95 LLPLRKHFKLFSNLRPARLYQGLEDFCPLRSDIAARGFDILCVRELTGGIYFGQPKG--R 152 Query: 185 NDKG-EETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI 361 +G E F+TE+Y EI+RIAR+AFE ARKR K+ S+DKANVL++S+LWR+ V I Sbjct: 153 EGQGMHERAFDTEVYHRFEIERIARIAFESARKRRSKVTSIDKANVLQSSILWREVVNGI 212 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 A+++PDV LSHMY+DNA MQL+++P QFD ++ +N+FGDILSDE +MITGS+GMLPSAS+ Sbjct: 213 AADYPDVALSHMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASL 272
>LEU3_YERPE (Q8ZIG9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 199 bits (506), Expect = 4e-51 Identities = 102/180 (56%), Positives = 137/180 (76%), Gaps = 2/180 (1%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVA-EGVDIMVVRELTGGIYFGKPRGFGT 184 LL +R +F+NLRPA + L D L+ ++A G DI+ VRELTGGIYFG+P+G Sbjct: 95 LLPLRKHFKLFSNLRPARLYQGLEDFCPLRSDIAARGFDILCVRELTGGIYFGQPKG--R 152 Query: 185 NDKG-EETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI 361 +G E F+TE+Y EI+RIAR+AFE ARKR K+ S+DKANVL++S+LWR+ V I Sbjct: 153 EGQGMHERAFDTEVYHRFEIERIARIAFESARKRRSKVTSIDKANVLQSSILWREVVNGI 212 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 A+++PDV LSHMY+DNA MQL+++P QFD ++ +N+FGDILSDE +MITGS+GMLPSAS+ Sbjct: 213 AADYPDVALSHMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASL 272
>LEU3_PHOLL (Q7N128) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 199 bits (506), Expect = 4e-51 Identities = 102/179 (56%), Positives = 136/179 (75%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVA-EGVDIMVVRELTGGIYFGKPRGFGT 184 LL +R +F+NLRPA + L L+ ++A +G DI+ VRELTGGIYFG+P+G Sbjct: 95 LLPLRKHFKLFSNLRPARLYAGLEVFCPLRNDIAAKGFDILCVRELTGGIYFGQPKGREG 154 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 K E F+TE+Y EI+RIAR+AFE ARKR K+ S+DKANVL++S+LWR+ VT IA Sbjct: 155 QGKYERA-FDTEVYHRFEIERIARIAFESARKRSNKVTSIDKANVLQSSVLWREVVTEIA 213 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 +PDVE++HMY+DNA MQL+++P QFD ++ +NIFGDILSDE +MITGS+GMLPSAS+ Sbjct: 214 KAYPDVEINHMYIDNATMQLIKDPSQFDVMLCSNIFGDILSDECAMITGSMGMLPSASL 272
>LEU3_VIBVY (Q7MP78) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 199 bits (505), Expect = 5e-51 Identities = 101/179 (56%), Positives = 136/179 (75%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVA-EGVDIMVVRELTGGIYFGKPRGFGT 184 LL +R +F NLRPA + L S L+ +++ G DI+VVRELTGGIYFG+P+G Sbjct: 96 LLPLRKHFQLFCNLRPAQIHSGLEAFSPLRADISGRGFDIVVVRELTGGIYFGQPKG-RE 154 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + E ++TEIY EI+RIA++AFE AR R K+CS+DKANVL++S+LWR+ V IA Sbjct: 155 GEGANEKAYDTEIYHRFEIERIAKIAFESARLRRKKVCSIDKANVLQSSILWREVVEEIA 214 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 ++PDVELSHMY+DNA MQL+++P QFD ++ +NIFGDI+SDE +MITGS+GMLPSAS+ Sbjct: 215 KDYPDVELSHMYIDNATMQLIKDPAQFDVMLCSNIFGDIISDECAMITGSMGMLPSASL 273
>LEU3_BUCAI (P56933) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 198 bits (504), Expect = 7e-51 Identities = 96/178 (53%), Positives = 137/178 (76%), Gaps = 1/178 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAE-GVDIMVVRELTGGIYFGKPRGFGT 184 LL +R +F+NLRPA + P+L S L+ ++ + G DI+ VRELTGGIYFG+P+GF Sbjct: 95 LLPLRKHFNLFSNLRPAKLYPELKCLSPLRSDIVKNGFDILCVRELTGGIYFGEPKGF-V 153 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 N + F+TEIY EI RIA +AF++AR R K+CS+DK+NVL++S+LWR+ V +++ Sbjct: 154 NKNNTKYAFDTEIYHEYEIIRIAHLAFKLARSRKKKVCSIDKSNVLQSSILWREVVESVS 213 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSAS 538 ++PDV LSH+Y+DNAAMQ++++P QFD ++ +N+FGDI+SDE + ITGSIGMLPSAS Sbjct: 214 KKYPDVHLSHLYIDNAAMQIIKDPNQFDVLLCSNLFGDIISDECATITGSIGMLPSAS 271
>LEU3_VIBVU (Q8DEE0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 198 bits (503), Expect = 9e-51 Identities = 100/179 (55%), Positives = 136/179 (75%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVA-EGVDIMVVRELTGGIYFGKPRGFGT 184 LL +R +F NLRPA + L S L+ +++ G DI+VVRELTGGIYFG+P+G Sbjct: 96 LLPLRKHFQLFCNLRPAQIHSGLEAFSPLRADISGRGFDIVVVRELTGGIYFGQPKG-RE 154 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + E ++TEIY EI+RIA++AFE AR R K+CS+DKANVL++S+LWR+ V +A Sbjct: 155 GEGANEKAYDTEIYHRFEIERIAKIAFESARLRRKKVCSIDKANVLQSSILWREVVEELA 214 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 ++PDVELSHMY+DNA MQL+++P QFD ++ +NIFGDI+SDE +MITGS+GMLPSAS+ Sbjct: 215 KDYPDVELSHMYIDNATMQLIKDPAQFDVMLCSNIFGDIISDECAMITGSMGMLPSASL 273
>LEU3_THEMA (Q9WZ26) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 354 Score = 197 bits (502), Expect = 1e-50 Identities = 102/181 (56%), Positives = 132/181 (72%), Gaps = 1/181 (0%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREV-AEGVDIMVVRELTGGIYFGKPRGFG 181 GLL +R L ++AN+RP V LV S LK +V GVD++ VREL+ G+Y+G+PRG Sbjct: 90 GLLALRKMLNLYANIRPIKVYRSLVHVSPLKEKVIGSGVDLVTVRELSYGVYYGQPRGLD 149 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI 361 EE GF+T IY ++RIAR AFE+A+ R K+ SVDKANVL +SMLWRK V + Sbjct: 150 -----EEKGFDTMIYDRKTVERIARTAFEIAKNRRKKVTSVDKANVLYSSMLWRKVVNEV 204 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 A E+PDVEL+H+YVDNAAMQL+ P QFD I+T N+FGDILSDE++ + GS+G+LPSAS Sbjct: 205 AREYPDVELTHIYVDNAAMQLILKPSQFDVILTTNMFGDILSDESAALPGSLGLLPSASF 264 Query: 542 G 544 G Sbjct: 265 G 265
>LEU3_ECOLI (P30125) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 197 bits (502), Expect = 1e-50 Identities = 101/179 (56%), Positives = 138/179 (77%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVA-EGVDIMVVRELTGGIYFGKPRGFGT 184 LL +R +F+NLRPA + L L+ ++A G DI+ VRELTGGIYFG+P+G Sbjct: 94 LLPLRKHFKLFSNLRPAKLYQGLEAFCPLRADIAANGFDILCVRELTGGIYFGQPKGREG 153 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + + E+ F+TE+Y EI+RIAR+AFE ARKR K+ S+DKANVL++S+LWR+ V IA Sbjct: 154 SGQYEKA-FDTEVYHRFEIERIARIAFESARKRRHKVTSIDKANVLQSSILWREIVNEIA 212 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 +E+PDVEL+HMY+DNA MQL+++P QFD ++ +N+FGDILSDE +MITGS+GMLPSAS+ Sbjct: 213 TEYPDVELAHMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASL 271
>LEU3_ECOL6 (Q8FL76) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 197 bits (502), Expect = 1e-50 Identities = 101/179 (56%), Positives = 138/179 (77%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVA-EGVDIMVVRELTGGIYFGKPRGFGT 184 LL +R +F+NLRPA + L L+ ++A G DI+ VRELTGGIYFG+P+G Sbjct: 94 LLPLRKHFKLFSNLRPAKLYQGLEAFCPLRADIAANGFDILCVRELTGGIYFGQPKGREG 153 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + + E+ F+TE+Y EI+RIAR+AFE ARKR K+ S+DKANVL++S+LWR+ V IA Sbjct: 154 SGQYEKA-FDTEVYHRFEIERIARIAFESARKRRHKVTSIDKANVLQSSILWREIVNEIA 212 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 +E+PDVEL+HMY+DNA MQL+++P QFD ++ +N+FGDILSDE +MITGS+GMLPSAS+ Sbjct: 213 TEYPDVELTHMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASL 271
>LEU3_SHISS (Q3Z5T7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 197 bits (502), Expect = 1e-50 Identities = 101/179 (56%), Positives = 138/179 (77%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVA-EGVDIMVVRELTGGIYFGKPRGFGT 184 LL +R +F+NLRPA + L L+ ++A G DI+ VRELTGGIYFG+P+G Sbjct: 95 LLPLRKRFKLFSNLRPAKLYQGLEAFCPLRADIAANGFDILCVRELTGGIYFGQPKGREG 154 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + + E+ F+TE+Y EI+RIAR+AFE ARKR K+ S+DKANVL++S+LWR+ V IA Sbjct: 155 SGQYEKA-FDTEVYHRFEIERIARIAFESARKRRHKVTSIDKANVLQSSILWREIVNEIA 213 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 +E+PDVEL+HMY+DNA MQL+++P QFD ++ +N+FGDILSDE +MITGS+GMLPSAS+ Sbjct: 214 TEYPDVELAHMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASL 272
>LEU3_SHIDS (Q32K21) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 197 bits (502), Expect = 1e-50 Identities = 101/179 (56%), Positives = 138/179 (77%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVA-EGVDIMVVRELTGGIYFGKPRGFGT 184 LL +R +F+NLRPA + L L+ ++A G DI+ VRELTGGIYFG+P+G Sbjct: 95 LLPLRKHFKLFSNLRPAKLYQGLEAFCPLRADIAANGFDILCVRELTGGIYFGQPKGREG 154 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + + E+ F+TE+Y EI+RIAR+AFE ARKR K+ S+DKANVL++S+LWR+ V IA Sbjct: 155 SGQYEKA-FDTEVYHRFEIERIARIAFESARKRRHKVTSIDKANVLQSSILWREIVNEIA 213 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 +E+PDVEL+HMY+DNA MQL+++P QFD ++ +N+FGDILSDE +MITGS+GMLPSAS+ Sbjct: 214 TEYPDVELAHMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASL 272
>LEU3_SHIBS (Q326G2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 197 bits (502), Expect = 1e-50 Identities = 101/179 (56%), Positives = 138/179 (77%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVA-EGVDIMVVRELTGGIYFGKPRGFGT 184 LL +R +F+NLRPA + L L+ ++A G DI+ VRELTGGIYFG+P+G Sbjct: 95 LLPLRKHFKLFSNLRPAKLYQGLEAFCPLRADIAANGFDILCVRELTGGIYFGQPKGREG 154 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + + E+ F+TE+Y EI+RIAR+AFE ARKR K+ S+DKANVL++S+LWR+ V IA Sbjct: 155 SGQYEKA-FDTEVYHRFEIERIARIAFESARKRRHKVTSIDKANVLQSSILWREIVNEIA 213 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 +E+PDVEL+HMY+DNA MQL+++P QFD ++ +N+FGDILSDE +MITGS+GMLPSAS+ Sbjct: 214 TEYPDVELAHMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASL 272
>LEU3_ECO57 (Q8X9Z9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 197 bits (501), Expect = 2e-50 Identities = 100/179 (55%), Positives = 138/179 (77%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVA-EGVDIMVVRELTGGIYFGKPRGFGT 184 LL +R +F+NLRPA + L L+ ++A G DI+ VRELTGGIYFG+P+G Sbjct: 94 LLPLRKHFKLFSNLRPAKLYQGLEAFCPLRADIAANGFDILCVRELTGGIYFGQPKGREG 153 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + + E+ F+TE+Y EI+RIAR+AFE ARKR K+ S+DKANVL++S+LWR+ V IA Sbjct: 154 SGQYEKA-FDTEVYHRFEIERIARIAFESARKRRHKVTSIDKANVLQSSILWREIVNEIA 212 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 +E+PD+EL+HMY+DNA MQL+++P QFD ++ +N+FGDILSDE +MITGS+GMLPSAS+ Sbjct: 213 TEYPDIELAHMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASL 271
>LEU3_SHIFL (Q83SP1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 197 bits (500), Expect = 2e-50 Identities = 101/179 (56%), Positives = 137/179 (76%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVA-EGVDIMVVRELTGGIYFGKPRGFGT 184 LL +R +F+NLRPA + L L+ ++A G DI VRELTGGIYFG+P+G Sbjct: 94 LLPLRKHFKLFSNLRPAKLYQGLEAFCPLRADIAANGFDIQCVRELTGGIYFGQPKGREG 153 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + + E+ F+TE+Y EI+RIAR+AFE ARKR K+ S+DKANVL++S+LWR+ V IA Sbjct: 154 SGQYEKA-FDTEVYHRFEIERIARIAFESARKRRHKVTSIDKANVLQSSILWREIVNEIA 212 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 +E+PDVEL+HMY+DNA MQL+++P QFD ++ +N+FGDILSDE +MITGS+GMLPSAS+ Sbjct: 213 TEYPDVELAHMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASL 271
>LEU3_BACME (P41019) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 367 Score = 197 bits (500), Expect = 2e-50 Identities = 104/179 (58%), Positives = 130/179 (72%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL IR L ++ANLRP T L DAS LK+E EGVD ++VRELTGG+YFGKP T Sbjct: 89 GLLAIRKELDLYANLRPVTFYDSLADASPLKKEYIEGVDFIIVRELTGGLYFGKPSDRRT 148 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + +ET +T Y EI+RI + + A R K+ SVDKANVLE+S +WR+ +A Sbjct: 149 -EGNKETVVDTLFYKRTEIERII-ASIDTAVNRRKKVTSVDKANVLESSRVWREVAEEVA 206 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 ++PDVEL HM VD+AAMQL+RNPK FD +VT N+FGDILSDEASM+TGS+GMLPSAS+ Sbjct: 207 KDYPDVELEHMLVDSAAMQLIRNPKYFDVVVTENMFGDILSDEASMLTGSLGMLPSASL 265
>LEU3_BACCA (P05644) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 366 Score = 196 bits (498), Expect = 4e-50 Identities = 105/179 (58%), Positives = 129/179 (72%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL IR L ++ANLRP LV S LK ++ +GVD ++VRELTGGIYFG+P Sbjct: 92 GLLAIRKQLDLYANLRPVVCYDSLVSRSPLKPDLVQGVDFVIVRELTGGIYFGQPSAVVE 151 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 N GEE +T +Y EI+RI R+AFE+AR R K+ SVDKANVL +S LWR+ +A Sbjct: 152 N--GEEKAVDTLLYKKEEIERIVRMAFELARGRRKKVTSVDKANVLSSSRLWREVAEEVA 209 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 +EFPDV L HM VD MQL+R PKQFD IVT N+FGDILSDEASM++GS+GMLPSAS+ Sbjct: 210 NEFPDVTLEHMLVD-MRMQLIRAPKQFDVIVTENMFGDILSDEASMLSGSLGMLPSASL 267
>LEU3_LEPIN (P24015) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 196 bits (498), Expect = 4e-50 Identities = 101/180 (56%), Positives = 138/180 (76%), Gaps = 2/180 (1%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREV-AEGVDIMVVRELTGGIYFGKPRGFGT 184 LL +R +FANLRPA + P+L +AS ++ ++ G+DI+++RELTGGIYFG+P+G Sbjct: 92 LLPLRKHFDLFANLRPAIIYPELKNASPVRSDIIGNGLDILILRELTGGIYFGQPKGREG 151 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI- 361 + + EE ++T YS EI+RIA+VAF+ ARKR K+ S+DKANVL S+ W++ V + Sbjct: 152 SGQ-EEFAYDTMKYSRREIERIAKVAFQAARKRNNKVTSIDKANVLTTSVFWKEVVIELH 210 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 EF DV+L+H+YVDNAAMQL+ NPKQFD ++ N+FGDILSDEAS+ITGSIGMLPSAS+ Sbjct: 211 KKEFSDVQLNHLYVDNAAMQLIVNPKQFDVVLCENMFGDILSDEASIITGSIGMLPSASL 270
>LEU3_LEPIC (Q72RH7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 196 bits (498), Expect = 4e-50 Identities = 101/180 (56%), Positives = 138/180 (76%), Gaps = 2/180 (1%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREV-AEGVDIMVVRELTGGIYFGKPRGFGT 184 LL +R +FANLRPA + P+L +AS ++ ++ G+DI+++RELTGGIYFG+P+G Sbjct: 92 LLPLRKHFDLFANLRPAIIYPELKNASPVRSDIIGNGLDILILRELTGGIYFGQPKGREG 151 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI- 361 + + EE ++T YS EI+RIA+VAF+ ARKR K+ S+DKANVL S+ W++ V + Sbjct: 152 SGQ-EEFAYDTMKYSRREIERIAKVAFQAARKRNNKVTSIDKANVLTTSVFWKEVVIELH 210 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 EF DV+L+H+YVDNAAMQL+ NPKQFD ++ N+FGDILSDEAS+ITGSIGMLPSAS+ Sbjct: 211 KKEFSDVQLNHLYVDNAAMQLIVNPKQFDVVLCENMFGDILSDEASIITGSIGMLPSASL 270
>LEU3_BACCO (P12010) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 366 Score = 195 bits (496), Expect = 6e-50 Identities = 102/179 (56%), Positives = 130/179 (72%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL +R +G+FANLRP L++AS LKRE E VD+++VRELTGG+YFG+P Sbjct: 91 GLLGLRKEMGLFANLRPVKAYATLLNASPLKRERVENVDLVIVRELTGGLYFGRPSE--R 148 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 GE +T Y+ EI+RI AF++A+ R KL SVDKANVLE+S +WR+ A Sbjct: 149 RGPGENEVVDTLAYTREEIERIIEKAFQLAQIRRKKLASVDKANVLESSRMWREIAEETA 208 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 ++PDVELSHM VD+ +MQL+ NP QFD IVT N+FGDILSDEAS+ITGS+GMLPSAS+ Sbjct: 209 KKYPDVELSHMLVDSTSMQLIANPGQFDVIVTENMFGDILSDEASVITGSLGMLPSASL 267
>LEU3_BUCRP (P48572) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 195 bits (496), Expect = 6e-50 Identities = 97/179 (54%), Positives = 133/179 (74%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAE-GVDIMVVRELTGGIYFGKPRGFGT 184 LL +R +F+NLRPA + L + S L+ + G DI+ VRELTGGIYFGKP+G Sbjct: 95 LLPLRKHFNLFSNLRPAKLYSDLKNLSPLRSNIVRNGFDILCVRELTGGIYFGKPKGRSK 154 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 N+ GE + F+TEIY EI RIA +AFE+A R K+CS+DK+NVL +S+LWR+ V ++ Sbjct: 155 NENGEYS-FDTEIYYDFEIKRIAHLAFELASSRRCKVCSIDKSNVLASSILWREIVEEVS 213 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 +P++ LSH+Y+DNA MQ+++NP QFD ++ +NIFGDI+SDE +MITGSIGMLPSAS+ Sbjct: 214 KNYPNIILSHLYIDNACMQIIKNPSQFDVLLCSNIFGDIISDECAMITGSIGMLPSASL 272
>LEU3_PSEHT (Q3IJS3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 194 bits (494), Expect = 1e-49 Identities = 101/180 (56%), Positives = 138/180 (76%), Gaps = 2/180 (1%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAE-GVDIMVVRELTGGIYFGKPRGFGT 184 LL +R G+F NLRPA +LP L AS L+ +++E G DI+ VRELTGGIYFG+ G Sbjct: 96 LLPLRKHFGLFCNLRPAQLLPALSTASPLRADISEQGFDILCVRELTGGIYFGEK---GR 152 Query: 185 NDKGE-ETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI 361 + +GE E+ F+T+ YS EI+RIAR AFE A+ R + SVDKANVL +S+LWR+ VT + Sbjct: 153 SGEGENESAFDTQRYSRKEIERIARFAFEAAKLRSSHVTSVDKANVLASSVLWREVVTEV 212 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 + ++P+V+L ++YVDNAAMQLV+ P QFD ++ +N+FGDILSDE +MITGS+G+LPSAS+ Sbjct: 213 SKDYPEVKLDYIYVDNAAMQLVKQPSQFDVLLCDNLFGDILSDECAMITGSMGLLPSASL 272
>LEU3_BUCML (Q9EVG3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 365 Score = 194 bits (493), Expect = 1e-49 Identities = 98/180 (54%), Positives = 131/180 (72%), Gaps = 2/180 (1%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTL--KREVAEGVDIMVVRELTGGIYFGKPRGFG 181 LL +R +F NLRPA + +L S L K + G DI+ +RELTGGIYFG+PRG Sbjct: 95 LLPLRKHFNLFYNLRPAKLYSELRFLSPLRSKTXIKNGFDILCIRELTGGIYFGEPRG-R 153 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI 361 E F+TE+Y EI+RIA VAF++AR R K+CS+DKANVL +S+LWR+ VT + Sbjct: 154 LKKNNIEYAFDTEVYYDYEINRIAHVAFQLARTRKNKVCSIDKANVLNSSLLWREIVTKV 213 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 + +PDV LSH+Y+DNA MQ+++NP QFD ++ +N+FGDILSDE ++ITGSIGMLPSAS+ Sbjct: 214 SKNYPDVHLSHLYIDNATMQIIQNPNQFDILLCSNLFGDILSDECAIITGSIGMLPSASL 273
>LEU3_SALTY (P37412) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 194 bits (493), Expect = 1e-49 Identities = 99/179 (55%), Positives = 136/179 (75%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVA-EGVDIMVVRELTGGIYFGKPRGFGT 184 LL +R +F+NLRPA + L L+ ++A G DI+ VRELTGGIYFG+P+G Sbjct: 95 LLPLRKHFKLFSNLRPAKLYQGLEAFCPLRADIAANGFDILCVRELTGGIYFGQPKGREG 154 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + + E+ F+TE+Y EI+RIAR+AFE ARKR K+ S+DKANVL++S+LWR+ V +A Sbjct: 155 SGQYEKA-FDTEVYHRFEIERIARIAFESARKRRRKVTSIDKANVLQSSILWREIVNDVA 213 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 +PDVEL+HMY+DNA MQL+++P QFD ++ +N+FGDILSDE +MITGS+GMLPSAS+ Sbjct: 214 KTYPDVELAHMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASL 272
>LEU3_SALTI (Q8Z9I1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 194 bits (493), Expect = 1e-49 Identities = 99/179 (55%), Positives = 136/179 (75%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVA-EGVDIMVVRELTGGIYFGKPRGFGT 184 LL +R +F+NLRPA + L L+ ++A G DI+ VRELTGGIYFG+P+G Sbjct: 95 LLPLRKHFKLFSNLRPAKLYQGLEAFCPLRADIAANGFDILCVRELTGGIYFGQPKGREG 154 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + + E+ F+TE+Y EI+RIAR+AFE ARKR K+ S+DKANVL++S+LWR+ V +A Sbjct: 155 SGQYEKA-FDTEVYHRFEIERIARIAFESARKRRRKVTSIDKANVLQSSILWREIVNDVA 213 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 +PDVEL+HMY+DNA MQL+++P QFD ++ +N+FGDILSDE +MITGS+GMLPSAS+ Sbjct: 214 KAYPDVELAHMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASL 272
>LEU3_SALPA (Q5PDG2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 194 bits (493), Expect = 1e-49 Identities = 99/179 (55%), Positives = 136/179 (75%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVA-EGVDIMVVRELTGGIYFGKPRGFGT 184 LL +R +F+NLRPA + L L+ ++A G DI+ VRELTGGIYFG+P+G Sbjct: 95 LLPLRKHFKLFSNLRPAKLYQGLEAFCPLRADIAANGFDILCVRELTGGIYFGQPKGREG 154 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + + E+ F+TE+Y EI+RIAR+AFE ARKR K+ S+DKANVL++S+LWR+ V +A Sbjct: 155 SGQYEKA-FDTEVYHRFEIERIARIAFESARKRRRKVTSIDKANVLQSSILWREIVNDVA 213 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 +PDVEL+HMY+DNA MQL+++P QFD ++ +N+FGDILSDE +MITGS+GMLPSAS+ Sbjct: 214 KTYPDVELAHMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASL 272
>LEU3_SALCH (Q57TE7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 194 bits (493), Expect = 1e-49 Identities = 99/179 (55%), Positives = 136/179 (75%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVA-EGVDIMVVRELTGGIYFGKPRGFGT 184 LL +R +F+NLRPA + L L+ ++A G DI+ VRELTGGIYFG+P+G Sbjct: 95 LLPLRKHFKLFSNLRPAKLYQGLEAFCPLRADIAANGFDILCVRELTGGIYFGQPKGREG 154 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + + E+ F+TE+Y EI+RIAR+AFE ARKR K+ S+DKANVL++S+LWR+ V +A Sbjct: 155 SGQYEKA-FDTEVYHRFEIERIARIAFESARKRRRKVTSIDKANVLQSSILWREIVNDVA 213 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 +PDVEL+HMY+DNA MQL+++P QFD ++ +N+FGDILSDE +MITGS+GMLPSAS+ Sbjct: 214 KTYPDVELAHMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASL 272
>LEU3_HAEIN (P43860) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 194 bits (492), Expect = 2e-49 Identities = 98/179 (54%), Positives = 135/179 (75%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVA-EGVDIMVVRELTGGIYFGKPRGFGT 184 LL +R +F NLRPAT+ L L+ ++A +G D++VVRELTGGIYFG+P+G Sbjct: 94 LLPLRKHFKLFCNLRPATLYKGLEKFCPLRADIAAKGFDMVVVRELTGGIYFGQPKG-RE 152 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 D + F+TE+Y EI+RIAR AFE A KR K+ SVDKANVL++S+LWR+ VT +A Sbjct: 153 GDGVQTKAFDTEVYYKYEIERIARAAFEAAMKRNKKVTSVDKANVLQSSILWRETVTEMA 212 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 ++P+V L H+Y+DNA MQL+++P+ FD ++ +NIFGDI+SDEA+MITGS+GMLPSAS+ Sbjct: 213 KDYPEVTLEHIYIDNATMQLIKSPESFDVLLCSNIFGDIISDEAAMITGSMGMLPSASL 271
>LEU3_BUCDN (O85071) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 193 bits (491), Expect = 2e-49 Identities = 99/179 (55%), Positives = 132/179 (73%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAE-GVDIMVVRELTGGIYFGKPRGFGT 184 LL +R F NLRP+ + +L S L+ ++ + G DI+ VRELTGGIYFGKPRG T Sbjct: 95 LLPLRKHFNFFCNLRPSNLYKELNFLSPLRNDIVKHGFDILCVRELTGGIYFGKPRGRVT 154 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 K F+TEIY EI RIA +AF++AR R KLCS+DKANVLE+S+LWR+ V ++ Sbjct: 155 KKK-LMYAFDTEIYYKFEIVRIAHLAFKLARSRKHKLCSIDKANVLESSILWREVVEEVS 213 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 E+PDV LSH+Y+DN MQ++++P QFD ++ +N+FGDI+SDE +MITGSIGMLPSAS+ Sbjct: 214 KEYPDVILSHLYIDNVCMQIIKDPNQFDVLLCSNLFGDIISDECAMITGSIGMLPSASL 272
>LEU3_DEHE1 (Q3Z896) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 365 Score = 193 bits (490), Expect = 3e-49 Identities = 96/179 (53%), Positives = 127/179 (70%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL +R GLG+FAN+RP V P LV+++ +K E+ +G D + +RELTGG+YF KP+ T Sbjct: 91 GLLALRRGLGLFANIRPVKVAPSLVNSAPIKAEIVKGTDFIFIRELTGGVYFAKPKKRWT 150 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 G ++ YS EI+RI RV FE+AR R KL SVDKANVL +S LWR+ V IA Sbjct: 151 TPSGIRKATDSMTYSEKEIERIVRVGFELARSRKKKLVSVDKANVLLSSRLWRQIVIEIA 210 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 ++PD+ + H+ VD AM+L+ P FD IVT N+FGDIL+DEASM+ GS+GMLPSAS+ Sbjct: 211 KDYPDITVEHILVDACAMKLILAPTYFDVIVTENMFGDILTDEASMLAGSMGMLPSASL 269
>LEU3_HAEI8 (Q4QLS3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 193 bits (490), Expect = 3e-49 Identities = 99/180 (55%), Positives = 136/180 (75%), Gaps = 2/180 (1%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVA-EGVDIMVVRELTGGIYFGKPRGFGT 184 LL +R +F NLRPAT+ L L+ ++A +G D++VVRELTGGIYFG+P+G Sbjct: 94 LLPLRKHFKLFCNLRPATLYKGLEKFCPLRADIAAKGFDMVVVRELTGGIYFGQPKG--R 151 Query: 185 NDKGEET-GFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI 361 +G +T F+TE+Y EI+RIAR AFE A KR K+ SVDKANVL++S+LWR+ VT + Sbjct: 152 EGEGSQTKAFDTEVYYKYEIERIARAAFEAAMKRNKKVTSVDKANVLQSSILWRETVTEM 211 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 A ++P+V L H+Y+DNA MQL++ P+ FD ++ +NIFGDI+SDEA+MITGS+GMLPSAS+ Sbjct: 212 AKDYPEVTLEHIYIDNATMQLIKAPESFDVLLCSNIFGDIISDEAAMITGSMGMLPSASL 271
>LEU3_BUCUO (Q9EVI1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 364 Score = 192 bits (489), Expect = 4e-49 Identities = 92/179 (51%), Positives = 131/179 (73%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVA-EGVDIMVVRELTGGIYFGKPRGFGT 184 LL +R +FANLRPA + +L S L+ + +G DI+ +RELTGGIYFG+P G Sbjct: 95 LLPLRKHFNLFANLRPAKIYSELKHLSPLRSNIVRDGFDILCIRELTGGIYFGQPSGRRL 154 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 E F+TEIY EI+RIA +AF++A+ R K+CS+DK+NVL +S+LW++ V ++ Sbjct: 155 EKNNIEYAFDTEIYYDYEINRIAHLAFQLAQSRSHKVCSIDKSNVLNSSILWKEIVQKVS 214 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 +PDV+LSH+Y+DNA MQ+++NP QFD ++ N+FGDI+SDE ++ITGSIGMLPSAS+ Sbjct: 215 KNYPDVDLSHLYIDNAIMQIIKNPNQFDVLLCPNLFGDIISDECAIITGSIGMLPSASL 273
>LEU3_BRUME (Q8YCX4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 192 bits (488), Expect = 5e-49 Identities = 96/181 (53%), Positives = 133/181 (73%), Gaps = 1/181 (0%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL +R + ++ANLRPA P L +S+LK EV EG+DI+++RELTGG+YFG+P+ Sbjct: 92 GLLRLRKDMQLYANLRPAICYPALAHSSSLKPEVIEGLDILILRELTGGVYFGEPKEIID 151 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 G++ G +T++Y EI+RIA VAFE+AR R K+ S++K NV+++ +LW + VTA Sbjct: 152 LGNGQKRGIDTQVYDTYEIERIADVAFELARTRRNKVTSMEKRNVMKSGVLWNQGVTARH 211 Query: 365 SE-FPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 E DV+L HM D MQLVR PKQFD I+T+N+FGD+LSD A+M+TGS+GMLPSAS+ Sbjct: 212 KEKHADVQLEHMLADAGGMQLVRWPKQFDVILTDNLFGDLLSDVAAMLTGSLGMLPSASL 271 Query: 542 G 544 G Sbjct: 272 G 272
>LEU3_BRUSU (Q8FVF3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 370 Score = 192 bits (487), Expect = 7e-49 Identities = 96/181 (53%), Positives = 133/181 (73%), Gaps = 1/181 (0%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL +R + ++ANLRPA P L +S+LK EV EG+DI+++RELTGG+YFG+P+ Sbjct: 92 GLLRLRKDMQLYANLRPAICYPALAHSSSLKPEVIEGLDILILRELTGGVYFGEPKEIID 151 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 G++ G +T++Y EI+RIA VAFE+AR R K+ S++K NV+++ +LW + VTA Sbjct: 152 LGNGQKRGIDTQVYDTYEIERIADVAFELARTRRNKVTSMEKRNVMKSGVLWNQVVTARH 211 Query: 365 SE-FPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 E DV+L HM D MQLVR PKQFD I+T+N+FGD+LSD A+M+TGS+GMLPSAS+ Sbjct: 212 KEKHADVQLEHMLADAGGMQLVRWPKQFDVILTDNLFGDLLSDVAAMLTGSLGMLPSASL 271 Query: 542 G 544 G Sbjct: 272 G 272
>LEU3_RHILO (Q98E57) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 367 Score = 192 bits (487), Expect = 7e-49 Identities = 96/181 (53%), Positives = 133/181 (73%), Gaps = 1/181 (0%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL +R + +FANLRPA P L +S+LK+EV EG+DI++VRELTGG+YFG+P+ Sbjct: 92 GLLRLRKDMELFANLRPAICYPALAASSSLKQEVVEGLDILIVRELTGGVYFGEPKQIID 151 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI- 361 G++ G +T++Y EI+RI+ VAFE+AR R + S++K NV+++ +LW + VT Sbjct: 152 LGNGQKRGIDTQVYDTFEIERISGVAFELARTRKNHVTSMEKRNVMKSGVLWNEVVTQTH 211 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 + + DV+L HM D MQLVR PKQFD IVT+N+FGD+LSD A+M+TGSIGMLPSAS+ Sbjct: 212 KARYADVKLDHMLADAGGMQLVRWPKQFDVIVTDNLFGDMLSDIAAMLTGSIGMLPSASL 271 Query: 542 G 544 G Sbjct: 272 G 272
>LEU3_VIBF1 (Q5E857) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 191 bits (486), Expect = 9e-49 Identities = 97/179 (54%), Positives = 135/179 (75%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAE-GVDIMVVRELTGGIYFGKPRGFGT 184 LL +R +F NLRPA + L + S L+ +++E G DI+VVRELTGGIYFG+P+G Sbjct: 96 LLPLRKHFQLFCNLRPAQIHKGLENFSPLRADISERGFDIVVVRELTGGIYFGQPKG-RE 154 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + +E ++TEIY EI+RIA++AFE AR R + S+DKANVL++S+LWR+ V +A Sbjct: 155 GEGPQEKAYDTEIYHRYEIERIAKIAFESARLRNKNVYSIDKANVLQSSILWREVVEEVA 214 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 +PDV L+HMY+DNA MQL+++P QFD ++ +NIFGDI+SDE +MITGS+GMLPSAS+ Sbjct: 215 KGYPDVTLNHMYIDNATMQLIKDPSQFDVMLCSNIFGDIISDECAMITGSMGMLPSASL 273
>LEU3_DEHSC (Q3ZXI7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 365 Score = 191 bits (484), Expect = 1e-48 Identities = 94/179 (52%), Positives = 128/179 (71%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL +R GLG+FAN+RP V P LV+++ +K E+ +G D + +RELTGG+YF KP+ T Sbjct: 91 GLLALRKGLGLFANIRPVKVAPSLVNSTPIKAEIVKGTDFIFIRELTGGVYFAKPKKRWT 150 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 G ++ YS EI+RI RV FE+A+ R KL SVDKANVL +S LWR+ V +A Sbjct: 151 TPAGIRKATDSMTYSENEIERIVRVGFELAKNRKKKLVSVDKANVLLSSRLWRQIVIEVA 210 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 ++P+V++ H+ VD AM+L+ P FD IVT N+FGDIL+DEASM+ GS+GMLPSAS+ Sbjct: 211 KDYPEVKVEHVLVDACAMKLILAPTYFDVIVTENLFGDILTDEASMLAGSMGMLPSASL 269
>LEU3_RHOBA (Q7UIE1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 359 Score = 191 bits (484), Expect = 1e-48 Identities = 100/182 (54%), Positives = 129/182 (70%), Gaps = 2/182 (1%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL IR LG+FANLRP + +L DAS L+ ++ +G DI+ RELTGGIYFG+ GT Sbjct: 91 GLLKIRKELGLFANLRPIKLFDELADASPLRADIVKGTDILFFRELTGGIYFGES---GT 147 Query: 185 NDKGEE-TGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI 361 + GEE T F + YSV E+ RI R+A + AR R +L SVDKANVLE S LWR+ + Sbjct: 148 SGSGEEETAFQSMTYSVGEVKRIVRMAAQAARGRSNRLTSVDKANVLEPSRLWRRVAAEV 207 Query: 362 -ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSAS 538 A+EFPDV+ + VD+ AM L+ P +FD +VT N+FGDIL+DEASM+ GS+GMLPSAS Sbjct: 208 MANEFPDVQYDVVLVDSMAMHLINRPSEFDVVVTGNMFGDILTDEASMLPGSLGMLPSAS 267 Query: 539 VG 544 +G Sbjct: 268 LG 269
>LEU3_ERWCT (Q6D0G7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 191 bits (484), Expect = 1e-48 Identities = 98/180 (54%), Positives = 135/180 (75%), Gaps = 2/180 (1%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVA-EGVDIMVVRELTGGIYFGKPRGFGT 184 LL +R +F+NLRPA + L L+ ++A +G DI+ VRELTGGIYFG+P+G Sbjct: 95 LLPLRKHFKLFSNLRPARLYQGLEAFCPLRSDIAAKGFDILCVRELTGGIYFGQPKG--R 152 Query: 185 NDKGE-ETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI 361 G+ E F+TE+Y EI+RIA +AFE ARKR + S+DKANVL++S+LWR+ VT + Sbjct: 153 EGSGQYERAFDTEVYHRFEIERIAHIAFESARKRRSIVTSIDKANVLQSSILWREIVTEV 212 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 A +PDV+LSH+Y+DNA MQL+++P QFD ++ +N+FGDILSDE +MITGS+GMLPSAS+ Sbjct: 213 AKAYPDVKLSHLYIDNATMQLIKDPSQFDVMLCSNLFGDILSDECAMITGSMGMLPSASL 272
>LEU3_BUCUS (Q9EVI4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 191 bits (484), Expect = 1e-48 Identities = 93/179 (51%), Positives = 131/179 (73%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAE-GVDIMVVRELTGGIYFGKPRGFGT 184 LL +R +F NLRPA + +L+ S L+ ++ G +I+ +RELTGGIYFGKP G Sbjct: 95 LLPLRKHFNLFGNLRPAQLYSELIHLSPLRSDIINNGFNILCIRELTGGIYFGKPAG-RL 153 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 E F+TEIY EI+RIA +AF++A+ R K+CS+DK+NVL +S+LWR+ V ++ Sbjct: 154 KKNNIEYAFDTEIYYNYEINRIAHLAFQLAKTRNYKVCSIDKSNVLNSSILWREIVQKVS 213 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 +PDV LSH+Y+DNA MQ+++NP QFD ++ +N+FGDI+SDE +MITGSIGMLPSAS+ Sbjct: 214 KNYPDVHLSHLYIDNATMQIIKNPNQFDILLCSNLFGDIISDECAMITGSIGMLPSASL 272
>LEU3_HELHP (Q7VH33) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 191 bits (484), Expect = 1e-48 Identities = 99/179 (55%), Positives = 132/179 (73%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAE-GVDIMVVRELTGGIYFGKPRGFGT 184 LL +R LG+FAN+RPAT+LPQL AS LK E+ G+D ++VREL GG+YFG+ + Sbjct: 92 LLTLRKELGLFANIRPATLLPQLSKASPLKDEILNRGIDFIIVRELIGGVYFGEHKLEEI 151 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 N GE+ + YS ++I+ IA+VAF +AR R ++ VDKANVL +S LWR+ V +A Sbjct: 152 N--GEKVASDAMTYSASQIESIAKVAFNIARNRKKEIVCVDKANVLSSSRLWREVVDKVA 209 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 + DV LS+MYVDNAAMQ+ R P QFD I+T N+FGDILSDEAS+ITG+IG++PSAS+ Sbjct: 210 QNYKDVHLSYMYVDNAAMQICRAPSQFDVILTENMFGDILSDEASIITGTIGVIPSASL 268
>LEU3_BUCUM (Q9EVG9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 365 Score = 190 bits (482), Expect = 3e-48 Identities = 92/180 (51%), Positives = 131/180 (72%), Gaps = 2/180 (1%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVA--EGVDIMVVRELTGGIYFGKPRGFG 181 LL +R +FANLRPA + +L S L+ ++ G +I+ +RELTGGIYFGKP G Sbjct: 95 LLPLRKHFNLFANLRPAQLYSELKYLSPLRSDIXIKNGFNILCIRELTGGIYFGKPTGRX 154 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI 361 E F+TEIY EI+RIA +AF++A+ R K+CS+DK+NVL +S+LWR+ V + Sbjct: 155 LKKNNIEYAFDTEIYYDYEINRIAHLAFQLAQTRNYKVCSIDKSNVLNSSVLWRETVQKV 214 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 + +PDV LSH+Y+DNA MQ++++P QFD ++ +N+FGDI+SDE ++ITGSIGMLPSAS+ Sbjct: 215 SKNYPDVHLSHLYIDNATMQIIKDPNQFDILLCSNLFGDIVSDECAIITGSIGMLPSASL 274
>LEU3_MANSM (Q65V05) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 189 bits (480), Expect = 4e-48 Identities = 97/180 (53%), Positives = 137/180 (76%), Gaps = 2/180 (1%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVA-EGVDIMVVRELTGGIYFGKPRGFGT 184 LL +R +F NLRPAT+ L L+ ++A +G D++VVRELTGGIYFG+P+G Sbjct: 94 LLPLRKHFKLFCNLRPATLYKGLEKFCPLRADIAAKGFDMVVVRELTGGIYFGQPKG--R 151 Query: 185 NDKGEET-GFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI 361 + +G +T F+TE+Y EI+RIAR AF+ A KR ++ SVDKANVL++S+LWR+ V I Sbjct: 152 DGEGSDTRAFDTEVYYKYEIERIARAAFDAAMKRRKQVTSVDKANVLQSSILWRETVAEI 211 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 A E+P+V++ +MY+DNA MQL++ P+ FD ++ +NIFGDI+SDEA+MITGS+GMLPSAS+ Sbjct: 212 AKEYPEVQVENMYIDNATMQLIKAPESFDVLLCSNIFGDIISDEAAMITGSMGMLPSASL 271
>LEU3_PHOPR (Q6LV25) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 189 bits (479), Expect = 6e-48 Identities = 96/179 (53%), Positives = 134/179 (74%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAE-GVDIMVVRELTGGIYFGKPRGFGT 184 LL +R +F NLRPA + L S L+ +++E G DI+VVRELTGGIYFG+P+G Sbjct: 95 LLPLRKHFQLFCNLRPAQIHSGLEGFSPLRADISERGFDIVVVRELTGGIYFGQPKG-RE 153 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + +E ++TEIY EI+RIAR+AFE A R + S+DKANVL++S+LWR+ V +A Sbjct: 154 GEGPQEKAYDTEIYHRYEIERIARIAFESAMLREKNVYSIDKANVLQSSILWREVVEEVA 213 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 ++P+V L+HMY+DNA MQL+++P QFD ++ +NIFGDI+SDE +MITGS+GMLPSAS+ Sbjct: 214 KDYPEVTLNHMYIDNATMQLIKDPSQFDVMLCSNIFGDIISDECAMITGSMGMLPSASL 272
>LEU3_BUCUA (Q9EVG6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 187 bits (476), Expect = 1e-47 Identities = 92/179 (51%), Positives = 132/179 (73%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAE-GVDIMVVRELTGGIYFGKPRGFGT 184 LL +R +FANLRPA + +L + S L+ + + G +I+ +RELTGGIYFGKP G Sbjct: 95 LLPLRKHFNLFANLRPAQLYSELKNLSPLRSNIIKNGFNILCIRELTGGIYFGKPTG-RL 153 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 E F+TEIY EI+RIA +AF++++ R K+CS+DK+NVL +S+LWR+ V ++ Sbjct: 154 KKNNIEYAFDTEIYYNYEINRIAHLAFQLSQTRNYKVCSIDKSNVLNSSILWREIVKKVS 213 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 +PDV LSH+Y+DNA MQ++++P QFD ++ +N+FGDI+SDE +MITGSIGMLPSAS+ Sbjct: 214 KHYPDVHLSHLYIDNATMQIIKDPNQFDVLLCSNLFGDIISDECAMITGSIGMLPSASL 272
>LEU3_BLOPB (Q493R1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 366 Score = 187 bits (475), Expect = 2e-47 Identities = 95/179 (53%), Positives = 129/179 (72%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLK-REVAEGVDIMVVRELTGGIYFGKPRGFGT 184 LL +R +FANLRP + +L + S L + G+DI+ VRELTGGIYFG+P+G Sbjct: 95 LLALRKHFNLFANLRPIYLADELKELSPLNINMIPNGIDIIFVRELTGGIYFGQPKGRSG 154 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 E F+T +Y EI+RIA +AF++A+KR ++ S+DKANVL SMLWR+ V+ +A Sbjct: 155 TGLNEYA-FDTAVYHRFEIERIANIAFKLAQKRRKRVSSIDKANVLHTSMLWREVVSHLA 213 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 +PDVEL H+Y+DNA+MQL+ NP +FD I+ N+FGDILSDE +MI+GSIGMLPSAS+ Sbjct: 214 KNYPDVELEHLYIDNASMQLINNPSKFDIILCPNLFGDILSDECAMISGSIGMLPSASI 272
>LEU3_BUCUH (Q9EVH8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 187 bits (475), Expect = 2e-47 Identities = 93/178 (52%), Positives = 129/178 (72%), Gaps = 1/178 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAE-GVDIMVVRELTGGIYFGKPRGFGT 184 LL +R +FANLRPA + +L S ++ + + G DI+ VRELTGGIYFGKP Sbjct: 95 LLPLRKHFNLFANLRPAKLYSELQHLSPIRSNIIKNGFDILCVRELTGGIYFGKPSD-RV 153 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 E F+TE+Y EI+RIA +AF++AR R K+CS+DK+NVL +S+LWR+ V ++ Sbjct: 154 KKNNVEYAFDTEVYYDYEINRIAHLAFQLARTRKFKVCSIDKSNVLNSSILWREVVEKVS 213 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSAS 538 +PDV LSH+Y+DNA MQ+++NP QFD ++ +N+FGDI+SDE ++ITGSIGMLPSAS Sbjct: 214 KMYPDVHLSHLYIDNATMQIIKNPNQFDVLLCSNLFGDIISDECAVITGSIGMLPSAS 271
>LEU3_BUCUD (Q9EVE1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 187 bits (474), Expect = 2e-47 Identities = 92/179 (51%), Positives = 131/179 (73%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAE-GVDIMVVRELTGGIYFGKPRGFGT 184 LL +R +FANLRPA + +L S L+ ++ + G DI+ +RELTGG+YFGKP G Sbjct: 95 LLPLRKHFNLFANLRPAKLYSELKYLSPLRSDIIKNGFDILCIRELTGGLYFGKPTG-RL 153 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 E F+TEIY EI RIA +AF++A+ R K+CS+DK+NVL +S+LWR+ V ++ Sbjct: 154 KKNNIEYAFDTEIYYNYEITRIAHLAFQLAQTRNFKICSIDKSNVLNSSVLWREIVKKVS 213 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 +PDV LSH+Y+DNA MQ++++P QFD ++ +N+FGDI+SDE ++ITGSIGMLPSAS+ Sbjct: 214 KNYPDVHLSHLYIDNATMQIIKDPNQFDILLCSNLFGDIISDECAIITGSIGMLPSASL 272
>LEU3_BUCUE (Q9EVH5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 364 Score = 186 bits (473), Expect = 3e-47 Identities = 94/179 (52%), Positives = 130/179 (72%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVA-EGVDIMVVRELTGGIYFGKPRGFGT 184 LL +R +F+NLRPA + L S L+ + +G DI+ VRELTGGIYFGKP G Sbjct: 95 LLPLRKHFNLFSNLRPAKLYADLKYLSPLRSNIIKDGFDILCVRELTGGIYFGKPNGHSK 154 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + E F+TE+Y EI RIA +AF++AR R K+CS+DK+NVL++S+LW++ V I+ Sbjct: 155 KND-IEYAFDTEVYYDYEISRIAHLAFQLARNRKKKVCSLDKSNVLKSSILWKEIVEKIS 213 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 +PDV LSH+Y+DNA MQ++++P QFD I+ +N+FGDI+SDE + ITGSIGMLPSAS+ Sbjct: 214 KNYPDVHLSHLYIDNAIMQIIKDPSQFDVILCSNLFGDIVSDECAAITGSIGMLPSASL 272
>LEU3_LISMO (Q8Y5R8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 350 Score = 186 bits (472), Expect = 4e-47 Identities = 95/178 (53%), Positives = 123/178 (69%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL +R LG+FAN+RP V + S LK+E+ E D +VVRELTGG+YFG+P+ + Sbjct: 89 GLLALRKALGLFANIRPIQVPSSITHLSPLKKEIVENTDFVVVRELTGGLYFGEPKHWD- 147 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 E ++ Y+ AEI+RI AFE+A R K+ SVDKANVL +S LWRK +A Sbjct: 148 ----ESAAVDSLTYTRAEIERIIEKAFEIAATRNKKVTSVDKANVLASSKLWRKIAEEVA 203 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSAS 538 S PD+ L H+Y+D AAM +++ P FD IVT N+FGDILSDEAS+ITGS+GMLPSAS Sbjct: 204 SRHPDITLEHLYIDAAAMLMIQRPTTFDVIVTENLFGDILSDEASVITGSLGMLPSAS 261
>LEU3_LISMF (Q71Y34) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 350 Score = 186 bits (472), Expect = 4e-47 Identities = 96/178 (53%), Positives = 123/178 (69%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL +R LG+FAN+RP V + S LK+E+ E D +VVRELTGG+YFG+P+ + Sbjct: 89 GLLALRKALGLFANIRPIQVPSSITHLSPLKKEIVENTDFVVVRELTGGLYFGEPKYWDN 148 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 E ++ Y+ AEI+RI AFE+A R K+ SVDKANVL +S LWRK +A Sbjct: 149 -----EAAVDSLTYTRAEIERIIEKAFEIAATRNKKVTSVDKANVLASSKLWRKIADEVA 203 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSAS 538 S PD+ L H+YVD AAM +++ P FD IVT N+FGDILSDEAS+ITGS+GMLPSAS Sbjct: 204 SRHPDITLEHLYVDAAAMLMIQRPTTFDVIVTENLFGDILSDEASVITGSLGMLPSAS 261
>LEU3_BUCTS (O31292) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 364 Score = 186 bits (471), Expect = 5e-47 Identities = 91/180 (50%), Positives = 130/180 (72%), Gaps = 1/180 (0%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAE-GVDIMVVRELTGGIYFGKPRGFG 181 GLL +R +FAN+RP + L+D S LK + + G+D++ +RELTGGIYFGK Sbjct: 95 GLLKLRKHFNLFANIRPCKLSQHLLDISPLKNSIIKKGIDLICIRELTGGIYFGKSNKIT 154 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI 361 D + F+TEIY +EI RIA++AF++A+ R K+ S+DKANVL++S+LWR V + Sbjct: 155 NID--DPYAFDTEIYFRSEIKRIAKIAFQIAQSRKKKIVSIDKANVLKSSILWRDTVNKM 212 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 A +FP+V+L HMY+DNA M+L++NP FD I+ +N+FGDI+SDE + I GSIG+LPSAS+ Sbjct: 213 AYKFPNVKLEHMYIDNATMELIKNPSSFDVILCSNLFGDIISDECAAIIGSIGLLPSASL 272
>LEU3_PASMU (Q9CJN6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 359 Score = 186 bits (471), Expect = 5e-47 Identities = 95/179 (53%), Positives = 130/179 (72%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREV-AEGVDIMVVRELTGGIYFGKPRGFGT 184 LL +R +F NLRPAT+ L L+ ++ A+G D++ VRELTGGIYFG+P+G Sbjct: 94 LLPLRKHFALFCNLRPATLYKGLEKFCPLRADISAKGFDMVTVRELTGGIYFGQPKG-RE 152 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + E F+TE+Y EI+RIARVAFE A KR + SVDKANVL +S+LWR+ V +A Sbjct: 153 GEGANEKAFDTEVYHRYEIERIARVAFETAMKRSKHVTSVDKANVLISSVLWREVVCDVA 212 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 ++P+V L H+Y+DNA MQL++ P+ FD ++ +NIFGDI+SDE +MITGS+GMLPSAS+ Sbjct: 213 KDYPEVTLDHIYIDNATMQLIKQPEFFDVLLCSNIFGDIISDECAMITGSMGMLPSASL 271
>LEU3_SHEON (Q8E9N3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 364 Score = 185 bits (470), Expect = 6e-47 Identities = 98/179 (54%), Positives = 128/179 (71%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREV-AEGVDIMVVRELTGGIYFGKPRGFGT 184 LL +R +F NLRPA + L S L+ ++ A G D++ VRELTGGIYFGKP+G Sbjct: 93 LLPLRGHFELFCNLRPAKLHDGLEHMSPLRSDISARGFDVLCVRELTGGIYFGKPKGRQG 152 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + EE F+T YS EI RIAR+AFE AR R K+ SVDKANVL S+LWR+ V +A Sbjct: 153 EGESEEA-FDTMRYSRREISRIARIAFEAARGRRKKVTSVDKANVLACSVLWRQVVEEVA 211 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 +FPDVEL H+Y+DNA MQL+R P +FD ++ +N+FGDILSDE +M+TGS+G+L SAS+ Sbjct: 212 VDFPDVELEHIYIDNATMQLLRRPDEFDVMLCSNLFGDILSDEIAMLTGSMGLLSSASM 270
>LEU3_BLOFL (Q7VQJ7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 364 Score = 185 bits (470), Expect = 6e-47 Identities = 95/179 (53%), Positives = 131/179 (73%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREV-AEGVDIMVVRELTGGIYFGKPRGFGT 184 LL +R +F NLRP + +L++ S LK E+ ++G+D++ +REL GGIYFGKP+G + Sbjct: 96 LLTLRKHFNLFINLRPIYLPIELINLSPLKPEIISQGLDMICIRELIGGIYFGKPQG-KS 154 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + +E F+T IY EI+RIA AF++A+KR + S+DKANVL SMLWRK V+ +A Sbjct: 155 GIRSQEHAFDTAIYHRFEIERIAHFAFKLAQKRRKHVTSIDKANVLHTSMLWRKVVSEVA 214 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 S +P+V L H+YVDNA+MQL+RNP FD I+ N+FGDILSDE + I GSIG+LPSAS+ Sbjct: 215 SNYPNVHLQHLYVDNASMQLIRNPSAFDVILCPNLFGDILSDECAEINGSIGILPSASL 273
>LEU3_CAMJE (Q9PLW0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 184 bits (468), Expect = 1e-46 Identities = 96/179 (53%), Positives = 129/179 (72%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAE-GVDIMVVRELTGGIYFGKPRGFGT 184 LL +R +FANLRP + L AS LK E+ + GVDI+ VRELTGGIYFGK Sbjct: 94 LLPLRKHFNLFANLRPCKIYESLTHASPLKNEIIQKGVDILCVRELTGGIYFGK------ 147 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 D G+E+ ++TEIY+ EI+RIAR+AFE AR R K+ +DKANVL +S+LWR+ V +A Sbjct: 148 QDLGKESAYDTEIYTKKEIERIARIAFESARIRKKKVHLIDKANVLASSILWREVVANVA 207 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 ++ D+ L +MYVDNAAMQ+V+NP FD ++ +N+FGDILSDE + I GS+G+L SAS+ Sbjct: 208 KDYQDINLEYMYVDNAAMQIVKNPSIFDVMLCSNLFGDILSDELAAINGSLGLLSSASL 266
>LEU3_BACCZ (Q63DX7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 354 Score = 184 bits (467), Expect = 1e-46 Identities = 98/178 (55%), Positives = 126/178 (70%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL +R GLGVFAN+RP TV + S LK+ A+ +D +VVRELTGGIYF P+ Sbjct: 89 GLLALRKGLGVFANVRPVTVESETAHLSPLKK--ADEIDFVVVRELTGGIYFSYPK---- 142 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 ++ +E +T Y EI+RI AF++A KR K+ S+DKANVLE+S LWR +A Sbjct: 143 -ERTDEVATDTLTYHRHEIERIVSYAFQLASKRKKKVTSIDKANVLESSKLWRTVTEEVA 201 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSAS 538 +PDVEL H+ VD AAM+L+RNP +FD IVT N+FGDILSDEAS++ GS+GMLPSAS Sbjct: 202 LRYPDVELEHILVDAAAMELIRNPGRFDVIVTENLFGDILSDEASVLAGSLGMLPSAS 259
>LEU3_STAS1 (Q49Z13) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 346 Score = 184 bits (466), Expect = 2e-46 Identities = 95/178 (53%), Positives = 121/178 (67%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL IR LG+FAN+RP TV S +K E D ++VRELTGGIYFG+P+ Sbjct: 89 GLLGIRKALGLFANIRPTTVTNGTSHLSPIKEERVANTDFILVRELTGGIYFGEPKQLSE 148 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 ND ++ Y+ EI+RIARV FE+A+KR KL SVDK NVL +S LWR + ++ Sbjct: 149 ND-----ALDSLTYTRDEIERIARVGFELAQKRHKKLTSVDKENVLSSSKLWRNVINEVS 203 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSAS 538 +PDVE++H+ VD AM L+ NP QFD IVT N+FGDILSDEAS+I GS+G+ PSAS Sbjct: 204 QSYPDVEVNHLLVDACAMHLITNPSQFDVIVTENLFGDILSDEASVIPGSLGLSPSAS 261
>LEU3_BACC1 (Q73B99) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 354 Score = 183 bits (464), Expect = 3e-46 Identities = 98/178 (55%), Positives = 125/178 (70%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL +R GLGVFAN+RP TV S LK+ A+ +D +VVRELTGGIYF P+ Sbjct: 89 GLLALRKGLGVFANVRPVTVESATAHLSPLKK--ADEIDFVVVRELTGGIYFSYPK---- 142 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 ++ +E +T Y EI+RI AF++A KR K+ S+DKANVLE+S LWR +A Sbjct: 143 -ERTDEVATDTLTYHRHEIERIVSYAFQLASKRKKKVTSIDKANVLESSKLWRTVTEEVA 201 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSAS 538 +PDVEL H+ VD AAM+L+RNP +FD IVT N+FGDILSDEAS++ GS+GMLPSAS Sbjct: 202 LRYPDVELEHILVDAAAMELIRNPGRFDVIVTENLFGDILSDEASVLAGSLGMLPSAS 259
>LEU3_LISIN (Q92A27) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 350 Score = 183 bits (464), Expect = 3e-46 Identities = 94/178 (52%), Positives = 122/178 (68%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL +R LG+FAN+RP V + S LK+E+ E D +VVRELTGG+YFG+P+ + Sbjct: 89 GLLALRKALGLFANIRPIQVPSSITHLSPLKKEIVENTDFVVVRELTGGLYFGEPKHWD- 147 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + ++ Y+ EI+RI AFE+A R K+ SVDKANVL +S LWRK +A Sbjct: 148 ----DVAAVDSLTYTRVEIERIIEKAFEIASTRNKKVTSVDKANVLASSKLWRKIAEEVA 203 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSAS 538 S PD+ L H+YVD AAM +++ P FD IVT N+FGDILSDEAS+ITGS+GMLPSAS Sbjct: 204 SRHPDITLEHLYVDAAAMLMIQRPTTFDVIVTENLFGDILSDEASVITGSLGMLPSAS 261
>LEU3_BUCBP (P59515) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 366 Score = 182 bits (463), Expect = 4e-46 Identities = 95/179 (53%), Positives = 129/179 (72%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAE-GVDIMVVRELTGGIYFGKPRGFGT 184 LL +R +F+NLR A + L S LK ++ G DI+ VRELTGGIYFG P+G Sbjct: 95 LLPLRKYFNLFSNLRLARIYSGLEKLSPLKSRISNLGCDILCVRELTGGIYFGDPKGSKV 154 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + K F+TE+Y EI+RIA +AF++A R K+ S+DKANVLE+SM WRK V I+ Sbjct: 155 S-KSLNCAFDTEVYYQFEIERIAHMAFDLALTRRCKVTSIDKANVLESSMFWRKIVNRIS 213 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 +++ V+LSH+YVDNAAMQ+++NP QFD ++ +N+FGDILSDE + ITGSIG+LPSAS+ Sbjct: 214 TQYSQVKLSHLYVDNAAMQIIKNPSQFDVLLCSNLFGDILSDECAAITGSIGLLPSASL 272
>LEU3_BACAN (Q81T67) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 354 Score = 182 bits (462), Expect = 5e-46 Identities = 98/178 (55%), Positives = 125/178 (70%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL +R GLGVFAN+RP TV S LK+ A+ +D +VVRELTGGIYF P+ Sbjct: 89 GLLALRKGLGVFANVRPVTVESATAHLSPLKK--ADEIDFVVVRELTGGIYFSYPK---- 142 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 ++ +E +T Y EI+RI AF++A KR K+ S+DKANVLE+S LWR +A Sbjct: 143 -ERTDEVATDTLTYHRHEIERIVSCAFQLASKRKKKVTSIDKANVLESSKLWRIVTEEVA 201 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSAS 538 +PDVEL H+ VD AAM+L+RNP +FD IVT N+FGDILSDEAS++ GS+GMLPSAS Sbjct: 202 LRYPDVELEHILVDAAAMELIRNPGRFDVIVTENLFGDILSDEASVLAGSLGMLPSAS 259
>LEU3_BACHK (Q6HLF2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 354 Score = 182 bits (461), Expect = 7e-46 Identities = 98/178 (55%), Positives = 124/178 (69%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL +R GLGVFAN+RP TV S LK+ A+ +D +VVRELTGGIYF P+ Sbjct: 89 GLLALRKGLGVFANVRPVTVESATAHLSPLKK--ADEIDFVVVRELTGGIYFSYPK---- 142 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + +E +T Y EI+RI AF++A KR K+ S+DKANVLE+S LWR +A Sbjct: 143 -KRTDEVATDTLTYHRHEIERIVSYAFQLASKRKKKVTSIDKANVLESSKLWRTVTEEVA 201 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSAS 538 +PDVEL H+ VD AAM+L+RNP +FD IVT N+FGDILSDEAS++ GS+GMLPSAS Sbjct: 202 LRYPDVELEHILVDAAAMELIRNPGRFDVIVTENLFGDILSDEASVLAGSLGMLPSAS 259
>LEU3_CAMJR (Q5HS77) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 358 Score = 181 bits (459), Expect = 1e-45 Identities = 94/179 (52%), Positives = 127/179 (70%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAE-GVDIMVVRELTGGIYFGKPRGFGT 184 LL +R +FANLRP + L AS LK E+ + GVDI+ VRELTGGIYFGK Sbjct: 94 LLPLRKHFNLFANLRPCKIYESLTHASPLKNEIIQKGVDILCVRELTGGIYFGK------ 147 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 D G+E+ ++TEIY+ EI+RIA +AFE AR R K+ +DKANVL +S+LWR+ V + Sbjct: 148 QDLGKESAYDTEIYTKKEIERIAHIAFESARIRKKKVHLIDKANVLASSILWREVVANVV 207 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 ++ D+ L +MYVDNAAMQ+V+NP FD ++ +N+FGDILSDE + I GS+G+L SAS+ Sbjct: 208 KDYQDINLEYMYVDNAAMQIVKNPSIFDVMLCSNLFGDILSDELAAINGSLGLLSSASL 266
>LEU3_BACCR (Q81G11) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 354 Score = 181 bits (458), Expect = 2e-45 Identities = 97/178 (54%), Positives = 124/178 (69%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL +R GLGVFAN+RP TV S LK A+ +D +VVRELTGGIYF P+ Sbjct: 89 GLLALRKGLGVFANVRPVTVESATAHLSPLKN--ADEIDFVVVRELTGGIYFSYPK---- 142 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 ++ EE +T Y EI+RI AF++A KR K+ S+DKANVLE+S LWR +A Sbjct: 143 -ERTEEVATDTLTYHRHEIERIVSYAFQLANKRKKKVTSIDKANVLESSKLWRTVTEEVA 201 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSAS 538 +P+VE+ H+ VD AAM+L+RNP +FD IVT N+FGDILSDEAS++ GS+GMLPSAS Sbjct: 202 LRYPNVEVEHILVDAAAMELIRNPGRFDVIVTENLFGDILSDEASVLAGSLGMLPSAS 259
>LEU3_STAAS (Q6G7Q0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 348 Score = 180 bits (456), Expect = 3e-45 Identities = 92/178 (51%), Positives = 122/178 (68%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL +R L +FAN+RP TV+ S LK E EG D+++VRELT GIYFG+PR F Sbjct: 89 GLLKLRKSLNLFANIRPTTVVKGASSLSPLKEERVEGTDLVIVRELTSGIYFGEPRHFNN 148 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 ++ ++ Y+ EI+RI VAF++A R GKL SVDK NVL +S LWRK V ++ Sbjct: 149 HE-----ALDSLTYTREEIERIVHVAFKLAASRRGKLTSVDKENVLASSKLWRKVVNEVS 203 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSAS 538 +P+V ++H+ VD +M L+ NPKQFD IV N+FGDILSDEAS+I GS+G+ PSAS Sbjct: 204 QLYPEVTVNHLLVDACSMHLITNPKQFDVIVCENLFGDILSDEASVIPGSLGLSPSAS 261
>LEU3_STAAN (P65101) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 348 Score = 180 bits (456), Expect = 3e-45 Identities = 92/178 (51%), Positives = 122/178 (68%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL +R L +FAN+RP TV+ S LK E EG D+++VRELT GIYFG+PR F Sbjct: 89 GLLKLRKSLNLFANIRPTTVVKGASSLSPLKEERVEGTDLVIVRELTSGIYFGEPRHFNN 148 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 ++ ++ Y+ EI+RI VAF++A R GKL SVDK NVL +S LWRK V ++ Sbjct: 149 HE-----ALDSLTYTREEIERIVHVAFKLAASRRGKLTSVDKENVLASSKLWRKVVNEVS 203 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSAS 538 +P+V ++H+ VD +M L+ NPKQFD IV N+FGDILSDEAS+I GS+G+ PSAS Sbjct: 204 QLYPEVTVNHLLVDACSMHLITNPKQFDVIVCENLFGDILSDEASVIPGSLGLSPSAS 261
>LEU3_STAAM (P65100) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 348 Score = 180 bits (456), Expect = 3e-45 Identities = 92/178 (51%), Positives = 122/178 (68%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL +R L +FAN+RP TV+ S LK E EG D+++VRELT GIYFG+PR F Sbjct: 89 GLLKLRKSLNLFANIRPTTVVKGASSLSPLKEERVEGTDLVIVRELTSGIYFGEPRHFNN 148 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 ++ ++ Y+ EI+RI VAF++A R GKL SVDK NVL +S LWRK V ++ Sbjct: 149 HE-----ALDSLTYTREEIERIVHVAFKLAASRRGKLTSVDKENVLASSKLWRKVVNEVS 203 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSAS 538 +P+V ++H+ VD +M L+ NPKQFD IV N+FGDILSDEAS+I GS+G+ PSAS Sbjct: 204 QLYPEVTVNHLLVDACSMHLITNPKQFDVIVCENLFGDILSDEASVIPGSLGLSPSAS 261
>LEU3_OCEIH (Q8EN68) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 366 Score = 179 bits (455), Expect = 3e-45 Identities = 98/179 (54%), Positives = 122/179 (68%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL IR LG+FANLRP + L+ AS LK E+ D++++RELTGGIYFG P T Sbjct: 91 GLLGIRKQLGLFANLRPVKTISSLLYASPLKEEIVSQADMLIIRELTGGIYFGTPSERTT 150 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 N +T YS EI+RI FE AR R L SVDKANVLE+S LWR+ V + Sbjct: 151 NGV-----VDTLQYSREEIERIVERGFEAARIRKKHLTSVDKANVLESSKLWREIVEEKS 205 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 ++PDV ++H+ VD AAM+LV P FD IVT N+FGDILSDEAS++TGS+GMLPSAS+ Sbjct: 206 KDYPDVAVNHLLVDAAAMKLVTQPSFFDVIVTENLFGDILSDEASVLTGSLGMLPSASL 264
>LEU3_STAAW (Q8NVJ0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 348 Score = 179 bits (454), Expect = 4e-45 Identities = 92/178 (51%), Positives = 122/178 (68%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL +R L +FAN+RP TV+ S LK E EG D+++VRELT GIYFG+PR F Sbjct: 89 GLLKLRKSLNLFANIRPTTVVKGASSLSPLKEERVEGKDLVIVRELTSGIYFGEPRHFNN 148 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 ++ ++ Y+ EI+RI VAF++A R GKL SVDK NVL +S LWRK V ++ Sbjct: 149 HE-----ALDSLTYTREEIERIVHVAFKLAASRRGKLTSVDKENVLASSKLWRKVVNEVS 203 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSAS 538 +P+V ++H+ VD +M L+ NPKQFD IV N+FGDILSDEAS+I GS+G+ PSAS Sbjct: 204 QLYPEVTVNHLLVDACSMHLITNPKQFDVIVCENLFGDILSDEASVIPGSLGLSPSAS 261
>LEU3_BUCUN (Q9EVI7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 364 Score = 179 bits (453), Expect = 6e-45 Identities = 90/180 (50%), Positives = 130/180 (72%), Gaps = 2/180 (1%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVA--EGVDIMVVRELTGGIYFGKPRGFG 181 LL +R +FANLRPA + +L S L + G +I+ VRELTGGIYFG+P G Sbjct: 95 LLPLRKHFNLFANLRPAQLYSELKYLSPLAFLIVIKNGFNILCVRELTGGIYFGQPSG-R 153 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI 361 + E F+TE+Y EI+RIA +AF++A+ R K+CS+DK+NVL +S+LWR+ V + Sbjct: 154 SKTNNFEYAFDTEVYYDYEINRIAHLAFQLAQTRNYKVCSIDKSNVLNSSILWREIVKKV 213 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 + +P+V LSH+Y+DNA MQ++++P QFD ++ +N+FGDI+SDE ++ITGSIGMLPSAS+ Sbjct: 214 SLSYPNVHLSHLYIDNATMQIIKDPNQFDVLLCSNLFGDIISDECAIITGSIGMLPSASL 273
>LEU3_STAAR (Q6GF15) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 348 Score = 179 bits (453), Expect = 6e-45 Identities = 92/178 (51%), Positives = 122/178 (68%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL +R L +FAN+RP TV+ S LK E EG D+++VRELT GIYFG+PR F Sbjct: 89 GLLKLRKSLNLFANIRPTTVVKGASSLSPLKAERVEGTDLVIVRELTSGIYFGEPRYFNN 148 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 ++ ++ Y+ EI+RI VAF++A R GKL SVDK NVL +S LWRK V ++ Sbjct: 149 HE-----ALDSLTYTREEIERIVHVAFKLAASRRGKLTSVDKENVLASSKLWRKVVNEVS 203 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSAS 538 +P+V ++H+ VD +M L+ NPKQFD IV N+FGDILSDEAS+I GS+G+ PSAS Sbjct: 204 QLYPEVTVNHLLVDACSMHLITNPKQFDVIVYENLFGDILSDEASVIPGSLGLSPSAS 261
>LEU3_STAAC (Q5HEE3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 348 Score = 178 bits (452), Expect = 8e-45 Identities = 91/178 (51%), Positives = 121/178 (67%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL +R L +F N+RP TV+ S LK E EG D+++VRELT GIYFG+PR F Sbjct: 89 GLLKLRKSLNLFVNIRPTTVVKGASSLSPLKEERVEGTDLVIVRELTSGIYFGEPRHFNN 148 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 ++ ++ Y+ EI+RI VAF++A R GKL SVDK NVL +S LWRK V ++ Sbjct: 149 HE-----ALDSLTYTREEIERIVHVAFKLAASRRGKLTSVDKENVLASSKLWRKVVNEVS 203 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSAS 538 +P+V ++H+ VD +M L+ NPKQFD IV N+FGDILSDEAS+I GS+G+ PSAS Sbjct: 204 QLYPEVTVNHLLVDACSMHLITNPKQFDVIVCENLFGDILSDEASVIPGSLGLSPSAS 261
>LEU3_DESPS (Q6ANR1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 177 bits (450), Expect = 1e-44 Identities = 94/180 (52%), Positives = 126/180 (70%), Gaps = 2/180 (1%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREV-AEGVDIMVVRELTGGIYFGKPRGFGT 184 LL +R +F N RPA V L A L+ ++ +G DI+ VRELT GIYFG P+G Sbjct: 92 LLPLRKHFDLFCNYRPARVFKSLTAACPLRADIIGDGFDILCVRELTSGIYFGTPKG--R 149 Query: 185 NDKGE-ETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI 361 GE E ++T Y +E+ RIA +AF AR+R GK+ SVDKANVL +LWR+ V + Sbjct: 150 EGAGEDEYAYDTMGYKRSEVRRIAHMAFAAARQRSGKVTSVDKANVLTTMVLWREVVLEV 209 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 A E+PDV+L+H+YVDNA MQLVR+P QFD ++ N+FGDI+SDEA+M+TGS+G+L SAS+ Sbjct: 210 AKEYPDVKLNHIYVDNATMQLVRDPHQFDVMLCGNMFGDIISDEAAMLTGSMGLLASASL 269
>LEU3_DEIRA (Q9RTH9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 352 Score = 176 bits (446), Expect = 4e-44 Identities = 91/182 (50%), Positives = 128/182 (70%), Gaps = 1/182 (0%) Frame = +2 Query: 2 TGLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFG 181 +GLL +R LG +ANLRP V P L S LK E+A GVDI++VREL GGIYF + R Sbjct: 88 SGLLALRKALGCYANLRPVRVQPGLEHLSPLKAELARGVDILIVRELLGGIYFDQDRKIE 147 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI 361 +T +NT Y+ +E++R+A+VAF A +R G++ SVDKANVLE S LWR+ V A+ Sbjct: 148 G-----DTAYNTMRYTTSEVERVAKVAFWAAEQRKGRVTSVDKANVLEVSELWRRDVQAL 202 Query: 362 AS-EFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSAS 538 ++ + L+H YVD+ AM +V +P ++D I+T N+FGDILSD A++I GS+G++PSAS Sbjct: 203 RDRDYRSIHLNHEYVDSVAMLIVADPSRYDVILTENLFGDILSDLAAVIPGSLGLMPSAS 262 Query: 539 VG 544 +G Sbjct: 263 LG 264
>LEU3_SORMA (Q6TWC4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 368 Score = 174 bits (440), Expect = 2e-43 Identities = 99/185 (53%), Positives = 127/185 (68%), Gaps = 5/185 (2%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQ-LVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFG 181 GLL +R LG + NLRP + LVD+S LK EV G D +VVRELTGGIYFG Sbjct: 93 GLLKLRKELGTYGNLRPCNFASESLVDSSPLKAEVCRGTDFIVVRELTGGIYFGDR---- 148 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVA--FEVARKRGGKLCSVDKANVLEASMLWRKRVT 355 T D G +TE YS AEI+RIAR+A +A+ K+ S+DKANVL S LWRK VT Sbjct: 149 TEDDGSGYACDTEPYSRAEIERIARLAGFLALAKNPPAKVWSLDKANVLATSRLWRKTVT 208 Query: 356 -AIASEFPDVELSHMYVDNAAMQLVRNPKQFD-TIVTNNIFGDILSDEASMITGSIGMLP 529 I+ EFP ++L H +D+AAM LV+NP+ + ++T+N+FGDI+SDEAS+I GSIG+LP Sbjct: 209 DVISKEFPQLQLEHQLIDSAAMLLVKNPRALNGVVITSNLFGDIISDEASVIPGSIGLLP 268 Query: 530 SASVG 544 SAS+G Sbjct: 269 SASLG 273
>LEU3_BACFR (P54354) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 353 Score = 174 bits (440), Expect = 2e-43 Identities = 90/180 (50%), Positives = 124/180 (68%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL +R LG+FAN+RP LV S L+ E+ EG D + +RELTGG+YFG+ + Sbjct: 92 GLLAMRKKLGLFANIRPVQTFKCLVHKSPLRAELVEGADFLCIRELTGGMYFGEK--YQD 149 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 NDK ++T +Y+ EI+RI +V FE A KR L VDKANVL +S LWR+ +A Sbjct: 150 NDKA----YDTNMYTRPEIERILKVGFEYAMKRRKHLTVVDKANVLASSRLWRQIAQEMA 205 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASVG 544 ++P+V +M+VDNAAM++++ PK FD +VT N FGDIL+DE S+I+GS+G+LPSAS G Sbjct: 206 PQYPEVTTDYMFVDNAAMKMIQEPKFFDVMVTENTFGDILTDEGSVISGSMGLLPSASTG 265
>LEU3_BACFN (Q5LAB4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 353 Score = 174 bits (440), Expect = 2e-43 Identities = 90/180 (50%), Positives = 124/180 (68%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL +R LG+FAN+RP LV S L+ E+ EG D + +RELTGG+YFG+ + Sbjct: 92 GLLAMRKKLGLFANIRPVQTFKCLVHKSPLRAELVEGADFLCIRELTGGMYFGEK--YQD 149 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 NDK ++T +Y+ EI+RI +V FE A KR L VDKANVL +S LWR+ +A Sbjct: 150 NDKA----YDTNMYTRPEIERILKVGFEYAMKRRKHLTVVDKANVLASSRLWRQIAQEMA 205 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASVG 544 ++P+V +M+VDNAAM++++ PK FD +VT N FGDIL+DE S+I+GS+G+LPSAS G Sbjct: 206 PQYPEVTTDYMFVDNAAMKMIQEPKFFDVMVTENTFGDILTDEGSVISGSMGLLPSASTG 265
>LEU3_STAES (Q8CNL2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 347 Score = 173 bits (439), Expect = 2e-43 Identities = 89/180 (49%), Positives = 120/180 (66%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL +R L +FAN+RP V S LK+++ EG D+++VRELT GIYFG+P Sbjct: 89 GLLKLRKSLNLFANIRPTFVTKGASHLSPLKQDIVEGTDLVIVRELTSGIYFGEPSYVKK 148 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + ++ YS EI+RI R+AF +A +R KL SVDK NVL +S LWR+ V + Sbjct: 149 TE-----ALDSLKYSSQEIERIVRIAFNLANRRRKKLTSVDKENVLSSSKLWRQIVNDVK 203 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASVG 544 ++P+VE++HM VD +M L+ P QFD IVT N+FGDILSDEAS+I GS+G+ PSAS G Sbjct: 204 KDYPEVEVNHMLVDACSMHLITQPTQFDVIVTENLFGDILSDEASVIPGSLGLSPSASFG 263
>LEU3_STAEQ (Q5HMF8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 347 Score = 173 bits (439), Expect = 2e-43 Identities = 89/180 (49%), Positives = 120/180 (66%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL +R L +FAN+RP V S LK+++ EG D+++VRELT GIYFG+P Sbjct: 89 GLLKLRKSLNLFANIRPTFVTKGASHLSPLKQDIVEGTDLVIVRELTSGIYFGEPSYVKK 148 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + ++ YS EI+RI R+AF +A +R KL SVDK NVL +S LWR+ V + Sbjct: 149 TE-----ALDSLKYSSQEIERIVRIAFNLANRRRKKLTSVDKENVLSSSKLWRQIVNDVK 203 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASVG 544 ++P+VE++HM VD +M L+ P QFD IVT N+FGDILSDEAS+I GS+G+ PSAS G Sbjct: 204 KDYPEVEVNHMLVDACSMHLITQPTQFDVIVTENLFGDILSDEASVIPGSLGLSPSASFG 263
>LEU3_STAHJ (Q4L7U1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 346 Score = 173 bits (438), Expect = 3e-43 Identities = 90/178 (50%), Positives = 118/178 (66%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL +R LG+FAN+RP V S +K +G D ++VRELT G+YFG+PR Sbjct: 89 GLLALRKSLGLFANIRPTKVTEGTSHFSPIKESRVKGTDFIIVRELTSGLYFGEPRHIDN 148 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 ++ ++ Y+ EI+RIA VAFE+A +R KL SVDK NVL S LWRK + I+ Sbjct: 149 -----QSALDSLTYTKKEIERIAMVAFELASQRKKKLTSVDKENVLATSKLWRKTINEIS 203 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSAS 538 EFPDV+++H+ VD +MQL+ P FD IVT N+FGDILSDEAS I GS+G+ PSAS Sbjct: 204 HEFPDVKVNHLLVDACSMQLISQPTNFDVIVTENLFGDILSDEASTIPGSLGLSPSAS 261
>LEU3_NEUCR (P34738) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 368 Score = 172 bits (435), Expect = 7e-43 Identities = 99/185 (53%), Positives = 126/185 (68%), Gaps = 5/185 (2%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQ-LVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFG 181 GLL +R LG + NLRP + LVD+S LK EV G D +VVRELTGGIYFG Sbjct: 93 GLLKLRKELGTYGNLRPCNFASESLVDSSPLKAEVCRGTDFIVVRELTGGIYFGDR---- 148 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVA--FEVARKRGGKLCSVDKANVLEASMLWRKRVT 355 T D G +TE YS AEI RIAR+A +A+ K+ S+DKANVL S LWRK VT Sbjct: 149 TEDDGSGYACDTEPYSRAEIVRIARLAGFLALAKNPPAKVWSLDKANVLATSRLWRKTVT 208 Query: 356 -AIASEFPDVELSHMYVDNAAMQLVRNPKQFD-TIVTNNIFGDILSDEASMITGSIGMLP 529 I+ EFP ++L H +D+AAM LV+NP+ + ++T+N+FGDI+SDEAS+I GSIG+LP Sbjct: 209 DVISKEFPQLQLEHQLIDSAAMLLVKNPRALNGVVITSNLFGDIISDEASVIPGSIGLLP 268 Query: 530 SASVG 544 SAS+G Sbjct: 269 SASLG 273
>LEU3_STRT2 (Q5M405) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 345 Score = 170 bits (431), Expect = 2e-42 Identities = 91/178 (51%), Positives = 119/178 (66%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL IR L +FAN+RP + L S LK E EGVD +VVRELTGGIYFG+ Sbjct: 89 GLLAIRKELNLFANIRPVRIFDALKHLSPLKPERIEGVDFVVVRELTGGIYFGE------ 142 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + E+ + YS EI RI R AF++A+ RG K+ S+DK NVL S LWRK ++ Sbjct: 143 HILEEDKARDINDYSADEIRRIMRRAFKIAQGRGKKVTSIDKQNVLATSKLWRKVADEVS 202 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSAS 538 EFPDV L H VD+AAM ++ NP +FD +VT N+FGDILSDE+S++ G++G++PSAS Sbjct: 203 LEFPDVTLEHQLVDSAAMIMITNPARFDVVVTENLFGDILSDESSVLPGTLGVMPSAS 260
>LEU3_STRT1 (Q5LZF3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 345 Score = 170 bits (431), Expect = 2e-42 Identities = 91/178 (51%), Positives = 119/178 (66%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL IR L +FAN+RP + L S LK E EGVD +VVRELTGGIYFG+ Sbjct: 89 GLLAIRKELNLFANIRPVRIFDALKHLSPLKPERIEGVDFVVVRELTGGIYFGE------ 142 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + E+ + YS EI RI R AF++A+ RG K+ S+DK NVL S LWRK ++ Sbjct: 143 HILEEDKARDINDYSADEIRRIMRRAFKIAQGRGKKVTSIDKQNVLATSKLWRKVADEVS 202 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSAS 538 EFPDV L H VD+AAM ++ NP +FD +VT N+FGDILSDE+S++ G++G++PSAS Sbjct: 203 LEFPDVTLEHQLVDSAAMIMITNPARFDVVVTENLFGDILSDESSVLPGTLGVMPSAS 260
>LEU3_BACTN (Q8A6M0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 353 Score = 168 bits (426), Expect = 8e-42 Identities = 88/180 (48%), Positives = 121/180 (67%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL +R LG+FAN+RP L+ S L+ E+ E D + +RELTGG+YFG+ + Sbjct: 92 GLLAMRKKLGLFANIRPVQTFKCLIHKSPLRAELVENADFICIRELTGGMYFGEK--YQD 149 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 NDK +T + Y+ EI+RI +VAFE A KR L VDKANVL +S LWR+ +A Sbjct: 150 NDKAYDTNY----YTRPEIERILKVAFEYAMKRRKHLTVVDKANVLASSRLWRQIAQEMA 205 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASVG 544 +P+V +M+VDNAAM++++ P FD +VT N FGDIL+DE S+I+GS+G+LPSAS G Sbjct: 206 PNYPEVTTDYMFVDNAAMKMIQEPAFFDVMVTENTFGDILTDEGSVISGSMGLLPSASTG 265
>LEU3_STRMU (Q8DTG3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 344 Score = 164 bits (415), Expect = 1e-40 Identities = 88/178 (49%), Positives = 115/178 (64%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL IR L +FAN+RP + L S LK E GVD +VVRELTGGIYFG+ Sbjct: 88 GLLAIRKELNLFANIRPVRIFDALRHLSPLKAERIAGVDFVVVRELTGGIYFGQ------ 141 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + E + + YS +EI RI R AF +AR R K+ S+DK NVL S LWR+ +A Sbjct: 142 HTLTENSACDINEYSASEIRRIMRKAFAIARGRSKKVTSIDKQNVLATSKLWRQIAEEVA 201 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSAS 538 E+ DV L H VD+AAM ++ NP FD +VT N+FGDILSDE+S++ G++G++PSAS Sbjct: 202 KEYSDVTLEHQLVDSAAMVMITNPACFDVVVTENLFGDILSDESSVLPGTLGVMPSAS 259
>LEU3_LACLA (Q02143) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 345 Score = 164 bits (414), Expect = 2e-40 Identities = 90/181 (49%), Positives = 117/181 (64%), Gaps = 1/181 (0%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GLL +R LG++AN+RP + P L S ++ E VD +V+RELTGGIYFG+ Sbjct: 89 GLLALRKELGLYANVRPLKIYPALKKLSPIRN--VENVDFLVIRELTGGIYFGQ------ 140 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLC-SVDKANVLEASMLWRKRVTAI 361 ++ ++ + YS EI RI AF+ A+ R KL SVDK NVL S LWRK I Sbjct: 141 HELADDKARDVNDYSADEIRRILHFAFKSAQSRPRKLLTSVDKQNVLATSKLWRKMADEI 200 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 A E+PDV L H VD+ AM L+ NP+QFD IVT N+FGDILSDEAS + GS+G++PS+S Sbjct: 201 ADEYPDVRLEHQLVDSCAMLLITNPQQFDVIVTENLFGDILSDEASSLAGSLGVMPSSSH 260 Query: 542 G 544 G Sbjct: 261 G 261
>LEU3_CANRU (Q9HDQ5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 359 Score = 163 bits (413), Expect = 3e-40 Identities = 94/184 (51%), Positives = 125/184 (67%), Gaps = 5/184 (2%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLP-QLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFG 181 GLL IR LG++ANLRP + +LVD S LKRE+ EG D +VVREL GGIYFG+ + Sbjct: 90 GLLKIRKELGLYANLRPCSFASSKLVDLSPLKREIVEGTDFVVVRELVGGIYFGERK--- 146 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRG--GKLCSVDKANVLEASMLWRKRVT 355 D G +TE YSV E++RI R+A +A + + S+DKANVL +S LWRK VT Sbjct: 147 -EDDGSGVASDTETYSVPEVERITRMAAFLALQHNPPQTVWSLDKANVLASSRLWRKTVT 205 Query: 356 AI-ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIV-TNNIFGDILSDEASMITGSIGMLP 529 + EFP V H +D+AAM LV+ P + + +V T+N+FGDI+SDEAS+I GS+G+LP Sbjct: 206 RVMTEEFPTVPFQHQLIDSAAMILVQKPTKLNGVVLTSNMFGDIISDEASVIPGSLGLLP 265 Query: 530 SASV 541 SAS+ Sbjct: 266 SASL 269
>LEU3_STRR6 (Q8DPJ4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 345 Score = 162 bits (410), Expect = 6e-40 Identities = 86/178 (48%), Positives = 115/178 (64%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 GL+ +R L ++AN+RP + L S LK E GVD +VVRELTG IYFG Sbjct: 89 GLMALRKELNLYANIRPVKIFDSLKYLSPLKPERISGVDFVVVRELTGEIYFGD------ 142 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAIA 364 + E + YS E++RI R AFE+AR R + S+DK NVL S LWRK +A Sbjct: 143 HILEERKARDINDYSYEEVERIIRKAFEIARNRRKIVTSIDKQNVLATSKLWRKVAEEVA 202 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSAS 538 +FPDV L H VD+AAM ++ NP +FD IVT N+FGDILSDE+S+++G++G++PSAS Sbjct: 203 QDFPDVTLEHQLVDSAAMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLGVMPSAS 260
>LEU3_ASHGO (O60027) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 372 Score = 162 bits (409), Expect = 7e-40 Identities = 93/184 (50%), Positives = 127/184 (69%), Gaps = 5/184 (2%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPAT-VLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFG 181 GLL +R LGV+ANLRP L++ S L+ E+A DIMVVREL GG YFG+ Sbjct: 92 GLLKLRQELGVYANLRPCNFAADSLLELSPLRPEIARDTDIMVVRELLGGSYFGERH--- 148 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKL--CSVDKANVLEASMLWRKRVT 355 D+G+ ++T+ Y+V E+ RIAR+A +A + L S+DKANVL +S LWRK V Sbjct: 149 -EDEGDGVAWDTDKYTVKEVQRIARMAGFLALQHDPPLPVWSLDKANVLASSRLWRKTVE 207 Query: 356 -AIASEFPDVELSHMYVDNAAMQLVRNPKQFD-TIVTNNIFGDILSDEASMITGSIGMLP 529 SEFP+V+L H +D+AAM LV+NP+ F+ +VT+N+FGDI+SDEAS+I GS+G+LP Sbjct: 208 ETFQSEFPNVQLQHQLIDSAAMILVKNPRAFNGVVVTSNMFGDIISDEASVIPGSLGLLP 267 Query: 530 SASV 541 SAS+ Sbjct: 268 SASL 271
>LEU3_KLULA (P23390) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 159 bits (403), Expect = 4e-39 Identities = 91/184 (49%), Positives = 127/184 (69%), Gaps = 5/184 (2%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQ-LVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFG 181 GLL IR LG++ANLRP L+D S LK E A+G D +VVREL GGIYFG+ + Sbjct: 90 GLLKIRKELGLYANLRPCNFASDSLLDLSPLKPEYAKGTDFVVVRELVGGIYFGERK--- 146 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKL--CSVDKANVLEASMLWRKRVT 355 D+G+ +++E YSV E+ RI R+A +A ++ L S+DKANVL +S LWRK V Sbjct: 147 -EDEGDGVAWDSEKYSVPEVQRITRMAAFLALQQNPPLPIWSLDKANVLASSRLWRKTVE 205 Query: 356 -AIASEFPDVELSHMYVDNAAMQLVRNPKQFD-TIVTNNIFGDILSDEASMITGSIGMLP 529 I +EFP + + H +D+AAM LV++P + + ++TNN+FGDI+SDEAS+I GS+G+LP Sbjct: 206 ETIKTEFPQLTVQHQLIDSAAMILVKSPTKLNGVVITNNMFGDIISDEASVIPGSLGLLP 265 Query: 530 SASV 541 SAS+ Sbjct: 266 SASL 269
>LEU3_KLUMA (P41766) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 359 Score = 159 bits (402), Expect = 5e-39 Identities = 93/184 (50%), Positives = 126/184 (68%), Gaps = 5/184 (2%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQ-LVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFG 181 GLL IR LG++ANLRP L+D S LK E A+G D +VVREL GGIYFG+ + Sbjct: 87 GLLKIRKELGLYANLRPCNFASDSLLDLSPLKPEYAKGTDFVVVRELVGGIYFGERK--- 143 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKL--CSVDKANVLEASMLWRKRVT 355 D+G+ +++E YSV E+ RI R+A +A + L S+DKANVL +S LWRK V Sbjct: 144 -EDEGDGVAWDSEKYSVPEVQRITRMAAFLALQHNPPLPIWSLDKANVLASSRLWRKTVE 202 Query: 356 -AIASEFPDVELSHMYVDNAAMQLVRNPKQFDTIV-TNNIFGDILSDEASMITGSIGMLP 529 I +EFP + + H +D+AAM LV++P + + IV TNN+FGDI+SDEAS+I GS+G+LP Sbjct: 203 ETIKNEFPQLTVQHQLIDSAAMILVKSPTKLNGIVITNNMFGDIISDEASVIPGSLGLLP 262 Query: 530 SASV 541 SAS+ Sbjct: 263 SASL 266
>LEU3_CANGA (O14429) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 365 Score = 159 bits (401), Expect = 6e-39 Identities = 92/184 (50%), Positives = 124/184 (67%), Gaps = 5/184 (2%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQ-LVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFG 181 GLL IR L ++ANLRP L+D S LK E+A G D +VVREL GGIYFG+ + Sbjct: 93 GLLKIRKELQLYANLRPCNFASDSLLDLSPLKPEIARGTDFVVVRELVGGIYFGERK--- 149 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKL--CSVDKANVLEASMLWRKRVT 355 D+G+ +++E YSV E+ RI R+A +A + L S+DKANVL +S LWRK V Sbjct: 150 -EDEGDGVAWDSEKYSVPEVQRITRMAAFMALQHNPPLPIWSLDKANVLASSRLWRKTVE 208 Query: 356 -AIASEFPDVELSHMYVDNAAMQLVRNPKQFD-TIVTNNIFGDILSDEASMITGSIGMLP 529 I +EFP + + H +D+AAM LV+NP + I+TNN+FGDI+SDEAS+I GS+G+LP Sbjct: 209 ETIKNEFPQLTVQHQLIDSAAMILVKNPTHLNGIIITNNMFGDIISDEASVIPGSLGLLP 268 Query: 530 SASV 541 SAS+ Sbjct: 269 SASL 272
>LEU3A_ASPNG (P87256) 3-isopropylmalate dehydrogenase A (EC 1.1.1.85) (Beta-IPM| dehydrogenase A) (IMDH A) (3-IPM-DH A) Length = 363 Score = 158 bits (400), Expect = 8e-39 Identities = 94/186 (50%), Positives = 122/186 (65%), Gaps = 7/186 (3%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPAT-VLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFG 181 GLLN+R +G F NLRP P LV+ S LK V EGVD ++RELTGGIYFG Sbjct: 91 GLLNVRKEMGTFGNLRPCNFAAPSLVEHSPLKASVCEGVDFNIIRELTGGIYFG------ 144 Query: 182 TNDKGEETG---FNTEIYSVAEIDRIA-RVAFEVARKRGGKLCSVDKANVLEASMLWRKR 349 D+ + T +TE YS AEI+RI R + + S+DKANVL S LWRK Sbjct: 145 --DRKKMTAAATMDTEPYSRAEIERITPRAHLALQHNPPLPVWSLDKANVLATSRLWRKT 202 Query: 350 VTAI-ASEFPDVELSHMYVDNAAMQLVRNPKQFD-TIVTNNIFGDILSDEASMITGSIGM 523 VT I A EFP +++ H +D+AAM +V+NP+Q + IVT+N+FGDI+SDEAS+I GS+G+ Sbjct: 203 VTEIMAKEFPQLKIEHQLIDSAAMIMVKNPRQLNGIIVTSNLFGDIISDEASVIPGSLGL 262 Query: 524 LPSASV 541 LPSAS+ Sbjct: 263 LPSASL 268
>LEU3_YARLI (P18120) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 405 Score = 158 bits (399), Expect = 1e-38 Identities = 90/184 (48%), Positives = 125/184 (67%), Gaps = 5/184 (2%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVL-PQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFG 181 GLL +R L ++ANLRP +L P+L D S ++ EG D ++VREL GGIYFG+ + Sbjct: 106 GLLKLRKDLNLYANLRPCQLLSPKLADLSPIRN--VEGTDFIIVRELVGGIYFGERK--- 160 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKL--CSVDKANVLEASMLWRKRVT 355 D G +TE YSV E++RIAR+A +A + L S+DKANVL +S LWRK VT Sbjct: 161 -EDDGSGVASDTETYSVPEVERIARMAAFLALQHNPPLPVWSLDKANVLASSRLWRKTVT 219 Query: 356 AIAS-EFPDVELSHMYVDNAAMQLVRNPKQFD-TIVTNNIFGDILSDEASMITGSIGMLP 529 + EFP +EL+H +D+AAM L++ P + + I+T N+FGDI+SDEAS+I GS+G+LP Sbjct: 220 RVLKDEFPQLELNHQLIDSAAMILIKQPSKMNGIIITTNMFGDIISDEASVIPGSLGLLP 279 Query: 530 SASV 541 SAS+ Sbjct: 280 SASL 283
>LEU3_MYCGR (Q9Y897) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 365 Score = 157 bits (398), Expect = 1e-38 Identities = 90/184 (48%), Positives = 124/184 (67%), Gaps = 5/184 (2%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQ-LVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFG 181 G+L +R +G + NLRP + LV S LK EV GV+ +VRELTGGIYFG+ Sbjct: 91 GILRLRKEMGTYGNLRPCFFASESLVKTSPLKEEVCRGVNFNIVRELTGGIYFGER---- 146 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVA--FEVARKRGGKLCSVDKANVLEASMLWRKRVT 355 T D G +TE YS AEI+R+AR+A +A + S+DKANV+ S LWRK VT Sbjct: 147 TEDDGSGYAVDTEPYSRAEIERVARLAGFLALAEDPPCPVWSLDKANVMATSRLWRKTVT 206 Query: 356 AI-ASEFPDVELSHMYVDNAAMQLVRNPKQFD-TIVTNNIFGDILSDEASMITGSIGMLP 529 + A+EFP +++ H +D+AAM +V+NP+ + IVT+N+FGDI+SDEAS+I GS+G+LP Sbjct: 207 DVFANEFPQLKIGHHLIDSAAMLMVKNPRALNGVIVTSNLFGDIISDEASVIPGSLGLLP 266 Query: 530 SASV 541 SAS+ Sbjct: 267 SASL 270
>LEU3_ARXAD (Q8NKB8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 157 bits (396), Expect = 2e-38 Identities = 90/184 (48%), Positives = 125/184 (67%), Gaps = 5/184 (2%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQ-LVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFG 181 GLL IR L ++ANLRP + + L+D S L+ E+ +G + VVREL GGIYFG + Sbjct: 90 GLLKIRKELNLYANLRPCNFMSEKLLDLSPLRSEIVKGTNFTVVRELVGGIYFGTRK--- 146 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKL--CSVDKANVLEASMLWRKRVT 355 D+G ++TE Y+V E+ RI R+A +A + L S+DKANVL +S LWRK VT Sbjct: 147 -EDEGNGEAWDTEKYTVEEVKRITRMAAFLALQSNPPLPVWSLDKANVLASSRLWRKTVT 205 Query: 356 -AIASEFPDVELSHMYVDNAAMQLVRNPKQFD-TIVTNNIFGDILSDEASMITGSIGMLP 529 I EFP + L+H +D+AAM L++NP + + IVT+N+FGDI+SDEAS+I GS+G+LP Sbjct: 206 ETIEKEFPQLTLNHQLIDSAAMILIQNPSKMNGVIVTSNMFGDIISDEASVIPGSLGLLP 265 Query: 530 SASV 541 SAS+ Sbjct: 266 SASL 269
>LEU3_PICJA (P08791) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 156 bits (395), Expect = 3e-38 Identities = 92/184 (50%), Positives = 122/184 (66%), Gaps = 5/184 (2%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQ-LVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFG 181 GLL IR L ++ANLRP + L+D S +K EV +G D +VVREL GGIYFG+ + Sbjct: 91 GLLKIRKELNLYANLRPCNFASESLLDLSPIKAEVVKGTDFVVVRELVGGIYFGERK--- 147 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKL--CSVDKANVLEASMLWRKRVT 355 D G +TE YSV E+ RI R+A +A + L S+DKANVL +S LWRK VT Sbjct: 148 -EDDGSGVASDTETYSVPEVQRITRMAAFMALQHNPPLPIWSLDKANVLASSRLWRKVVT 206 Query: 356 -AIASEFPDVELSHMYVDNAAMQLVRNPKQFDTIV-TNNIFGDILSDEASMITGSIGMLP 529 I EFP + + H +D+AAM L++ P Q + IV T+N+FGDI+SDEAS+I GS+G+LP Sbjct: 207 ETIEKEFPQLTVQHQLIDSAAMILIKYPTQLNGIVITSNMFGDIISDEASVIPGSLGLLP 266 Query: 530 SASV 541 SAS+ Sbjct: 267 SASL 270
>LEU3_SACEX (Q96WT9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 365 Score = 156 bits (394), Expect = 4e-38 Identities = 89/184 (48%), Positives = 124/184 (67%), Gaps = 5/184 (2%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQ-LVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFG 181 GLL IR L ++ANLRP L+D S LK E+ +G DI +VREL GGIYFG+ + Sbjct: 93 GLLKIRKELQLYANLRPCNFASDSLLDLSPLKPEIVKGTDICIVRELVGGIYFGERK--- 149 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKL--CSVDKANVLEASMLWRKRVT 355 D+G+ +++E YSV+E+ RI R+A +A + L S+DKANVL +S LWRK V Sbjct: 150 -EDEGDGVAWDSEKYSVSEVQRITRMAGFLALQHNPPLPVWSLDKANVLASSRLWRKTVE 208 Query: 356 -AIASEFPDVELSHMYVDNAAMQLVRNPKQFD-TIVTNNIFGDILSDEASMITGSIGMLP 529 I +EFP + + H +D+AAM LV+NP + ++ NN+FGDI+SDEAS+I GS+G+LP Sbjct: 209 ETIKNEFPTLTVQHQLIDSAAMILVKNPTHLNGVVIANNMFGDIISDEASVIPGSLGLLP 268 Query: 530 SASV 541 SAS+ Sbjct: 269 SASL 272
>LEU3_CANMI (Q6PY58) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 363 Score = 156 bits (394), Expect = 4e-38 Identities = 91/184 (49%), Positives = 122/184 (66%), Gaps = 5/184 (2%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPAT-VLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFG 181 GLL IR LG++ANLRP L+D S LK E A G D VVREL GIYFGK + Sbjct: 92 GLLKIRKELGLYANLRPCNFAFDSLLDMSPLKPEYARGTDFTVVRELVCGIYFGKRK--- 148 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKL--CSVDKANVLEASMLWRKRVT 355 D G+ +++E YSV E+ RI R+A +A + L S+DKANVL +S LWRK V Sbjct: 149 -EDTGDGVTWDSEQYSVPEVQRITRMAASLALQHNPPLPIWSLDKANVLASSRLWRKTVE 207 Query: 356 -AIASEFPDVELSHMYVDNAAMQLVRNPKQFD-TIVTNNIFGDILSDEASMITGSIGMLP 529 I +EFP + + H +D+AAM LV+NP + + ++T+N+FGDI+SDEAS+I GS+G+LP Sbjct: 208 ETIKNEFPTLSVQHQLIDSAAMILVKNPTKLNGLVITSNMFGDIISDEASVIPGSLGLLP 267 Query: 530 SASV 541 SAS+ Sbjct: 268 SASL 271
>LEU3_PICAN (P34733) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 154 bits (389), Expect = 2e-37 Identities = 91/184 (49%), Positives = 122/184 (66%), Gaps = 5/184 (2%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQ-LVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFG 181 GLL IR L ++ANLRP + L+ S LK E+ +G D +VVREL GGIYFG + Sbjct: 89 GLLKIRKELNLYANLRPCSFASDALLKLSPLKSEIVKGTDFVVVRELVGGIYFGDRK--- 145 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKL--CSVDKANVLEASMLWRKRVT 355 D G+ +TE YSV E+ RI R+A +A + L S+DKANVL +S LWRK V Sbjct: 146 -EDAGDGVASDTESYSVPEVQRITRMAAFLALQSDPPLPLWSLDKANVLASSRLWRKTVE 204 Query: 356 -AIASEFPDVELSHMYVDNAAMQLVRNPKQFD-TIVTNNIFGDILSDEASMITGSIGMLP 529 I +EFP + + H +D+AAM LV++P + + IVTNN+FGDI+SDEAS+I GS+G+LP Sbjct: 205 ETIKNEFPQLTVQHQLIDSAAMILVKSPTKLNGVIVTNNMFGDIISDEASVIPGSLGLLP 264 Query: 530 SASV 541 SAS+ Sbjct: 265 SASL 268
>LEU3_HANAN (Q9HDQ1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 364 Score = 153 bits (387), Expect = 3e-37 Identities = 90/184 (48%), Positives = 121/184 (65%), Gaps = 5/184 (2%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQ-LVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFG 181 GLL IR L ++ANLRP + L++ S +K E A+G D VVREL GGIYFG+ + Sbjct: 91 GLLKIRKELNLYANLRPCNFASESLLELSPIKAEFAKGTDFTVVRELVGGIYFGERK--- 147 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKL--CSVDKANVLEASMLWRKRVT 355 D G +TE YSV E+ RI R+A +A + L S+DKANVL +S LWRK VT Sbjct: 148 -EDDGSGVASDTETYSVPEVQRITRMAAFMALQHNPPLPIWSLDKANVLASSRLWRKTVT 206 Query: 356 -AIASEFPDVELSHMYVDNAAMQLVRNPKQFDTIV-TNNIFGDILSDEASMITGSIGMLP 529 I EFP + + H +D+AAM L+++P + IV T+N+FGDI+SDEAS+I GS+G+LP Sbjct: 207 ETIEKEFPQLTVQHQLIDSAAMILIKSPTTLNGIVITSNMFGDIISDEASVIPGSLGLLP 266 Query: 530 SASV 541 SAS+ Sbjct: 267 SASL 270
>LEU3_YEAST (P04173) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 364 Score = 153 bits (386), Expect = 3e-37 Identities = 89/184 (48%), Positives = 124/184 (67%), Gaps = 5/184 (2%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQ-LVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFG 181 GLL IR L ++ANLRP L+D S +K + A+G D +VVREL GGIYFGK + Sbjct: 92 GLLKIRKELQLYANLRPCNFASDSLLDLSPIKPQFAKGTDFVVVRELVGGIYFGKRK--- 148 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKL--CSVDKANVLEASMLWRKRVT 355 D G+ +++E Y+V E+ RI R+A +A + L S+DKANVL +S LWRK V Sbjct: 149 -EDDGDGVAWDSEQYTVPEVQRITRMAAFMALQHEPPLPIWSLDKANVLASSRLWRKTVE 207 Query: 356 -AIASEFPDVELSHMYVDNAAMQLVRNPKQFD-TIVTNNIFGDILSDEASMITGSIGMLP 529 I +EFP +++ H +D+AAM LV+NP + I+T+N+FGDI+SDEAS+I GS+G+LP Sbjct: 208 ETIKNEFPTLKVQHQLIDSAAMILVKNPTHLNGIIITSNMFGDIISDEASVIPGSLGLLP 267 Query: 530 SASV 541 SAS+ Sbjct: 268 SASL 271
>LEU3_ZYGRO (Q96WI0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 153 bits (386), Expect = 3e-37 Identities = 89/184 (48%), Positives = 127/184 (69%), Gaps = 5/184 (2%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQ-LVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFG 181 GLL IR L ++ANLRP + L+D S LK + A+G D +VVREL GGIYFG+ + Sbjct: 90 GLLKIRKELQLYANLRPCNFASESLLDLSPLKPQHAKGTDFVVVRELVGGIYFGERK--- 146 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKL--CSVDKANVLEASMLWRKRVT 355 D+G+ +++E Y+ E+ R+ R+A +A + L S+DKANVL +S LWRK V Sbjct: 147 -EDEGDGVAWDSEKYTKPEVQRLTRMAAFLALQHNPPLPIWSLDKANVLASSRLWRKTVE 205 Query: 356 -AIASEFPDVELSHMYVDNAAMQLVRNPKQFDTIV-TNNIFGDILSDEASMITGSIGMLP 529 I +EFP ++L+H +D+AAM LV++P Q + IV T+N+FGDI+SDEAS+I GS+G+LP Sbjct: 206 ETIKNEFPQLKLNHQLIDSAAMILVKSPTQLNGIVLTSNLFGDIISDEASVIPGSLGLLP 265 Query: 530 SASV 541 SAS+ Sbjct: 266 SASL 269
>LEU3_PHACH (O59930) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 380 Score = 152 bits (385), Expect = 4e-37 Identities = 90/182 (49%), Positives = 123/182 (67%), Gaps = 4/182 (2%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQ-LVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGT 184 LL +R LG++AN+RPA L+ S LK VA GVDI+V+REL GG YFG+ + G Sbjct: 95 LLALRKALGLYANIRPANFASDSLLAYSPLKPSVARGVDIIVIRELIGGAYFGERKELGA 154 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGG-KLCSVDKANVLEASMLWRKRVT-A 358 + E+ ++T IYSV E+ RI R +VA + S+DKANVL +S LWRK T Sbjct: 155 RAQ-EDAAWDTMIYSVPEVQRITRSRRQVASPDPPLPVHSIDKANVLASSRLWRKVATET 213 Query: 359 IASEFPDVELSHMYVDNAAMQLVRNPKQFD-TIVTNNIFGDILSDEASMITGSIGMLPSA 535 I +EFP ++L H VD+A+M +V NPK+ + I+T N+FGDILSDE+S+I GS+G+LPSA Sbjct: 214 IQNEFPQLKLDHHLVDSASMLIVANPKKLNGVILTENLFGDILSDESSVIPGSLGLLPSA 273 Query: 536 SV 541 S+ Sbjct: 274 SL 275
>LEU3_YAMOH (P41926) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 368 Score = 152 bits (384), Expect = 6e-37 Identities = 89/184 (48%), Positives = 125/184 (67%), Gaps = 5/184 (2%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPAT-VLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFG 181 GLL IR L ++ANLRP V L++ S LK E+ +G + VVREL GGIYFG+ + Sbjct: 90 GLLKIRKELNLYANLRPCNFVSDSLLELSPLKSEIVKGTNFTVVRELVGGIYFGERQEQE 149 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKL--CSVDKANVLEASMLWRKRVT 355 + G+ + ++TE YSV E+ RI R+A +A + L S+DKANVL S LWRK V Sbjct: 150 ESSDGQ-SAWDTEKYSVEEVTRITRMAAFMALQHNPPLPIWSLDKANVLALSRLWRKTVD 208 Query: 356 AIAS-EFPDVELSHMYVDNAAMQLVRNPKQFD-TIVTNNIFGDILSDEASMITGSIGMLP 529 + S EFP +++ H +D+AAM LV++P Q + I+T+N+FGDI+SDEAS+I GS+G+LP Sbjct: 209 HVMSTEFPQLKVQHQLIDSAAMILVKSPSQLNGVIITSNMFGDIISDEASVIPGSLGLLP 268 Query: 530 SASV 541 SAS+ Sbjct: 269 SASL 272
>LEU3_CANBO (Q01987) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 365 Score = 149 bits (377), Expect = 4e-36 Identities = 89/184 (48%), Positives = 120/184 (65%), Gaps = 5/184 (2%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLP-QLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFG 181 GLL IR L ++ANLRP +L+D S LK ++ +G D VVREL GGIYFG Sbjct: 93 GLLKIRKELNLYANLRPCNFASDKLLDLSPLKSDIVKGTDFTVVRELVGGIYFGDR---- 148 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKL--CSVDKANVLEASMLWRKRVT 355 D G ++E YSV E++RI R+A ++ + L S+DKANVL +S LWRK V Sbjct: 149 VEDDGSGFASDSESYSVPEVERITRMAAFLSLQNDPPLPIWSLDKANVLASSRLWRKTVD 208 Query: 356 -AIASEFPDVELSHMYVDNAAMQLVRNPKQFDTIV-TNNIFGDILSDEASMITGSIGMLP 529 I EFP + + H +D+AAM LV++P + + IV TNN+FGDI+SDEAS+I GS+G+LP Sbjct: 209 RVIKEEFPKLTVQHQLIDSAAMILVKSPTKLNGIVITNNMFGDIISDEASVIPGSLGLLP 268 Query: 530 SASV 541 SAS+ Sbjct: 269 SASL 272
>LEU3_SCHPO (P18869) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 371 Score = 149 bits (377), Expect = 4e-36 Identities = 89/184 (48%), Positives = 119/184 (64%), Gaps = 5/184 (2%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQ-LVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFG 181 GLL +R +GV+ANLRP + LV S LK E+ EGVD VVRELTGG YFG+ Sbjct: 91 GLLKLRKSMGVWANLRPCNFASKSLVKYSPLKPEIVEGVDFCVVRELTGGCYFGER---- 146 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRG--GKLCSVDKANVLEASMLWRKRVT 355 T D G +T YS+ E+ RIAR+A +A + +DKANVL S LWRK V Sbjct: 147 TEDNGSGYAMDTWPYSLEEVSRIARLAAWLAETSNPPAPVTLLDKANVLATSRLWRKTVA 206 Query: 356 AI-ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIV-TNNIFGDILSDEASMITGSIGMLP 529 I E+P + L + +D+AAM LV++P+ + +V T+N+FGDI+SDEAS+I GS+G+LP Sbjct: 207 KIFKEEYPHLTLKNQLIDSAAMLLVKSPRTLNGVVLTDNLFGDIISDEASVIPGSLGLLP 266 Query: 530 SASV 541 SAS+ Sbjct: 267 SASL 270
>LEU3_DEBHA (Q6B458) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 382 Score = 149 bits (376), Expect = 5e-36 Identities = 87/184 (47%), Positives = 122/184 (66%), Gaps = 5/184 (2%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQ-LVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFG 181 GLL IR L ++ANLRP L++ S LK E+ +G D VVREL GGIYFG+ R Sbjct: 104 GLLKIRKELNLYANLRPCNFASDSLLELSPLKSEIVKGTDFTVVRELVGGIYFGE-RQEQ 162 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKL--CSVDKANVLEASMLWRKRVT 355 + ++T ++TE YS E+ RI R+A +A + L S+DKANVL +S LWR V Sbjct: 163 AESEDKQTAWDTEKYSTEEVTRITRMAAFMALQHNPPLPIWSLDKANVLASSRLWRTTVD 222 Query: 356 AIASE-FPDVELSHMYVDNAAMQLVRNPKQFD-TIVTNNIFGDILSDEASMITGSIGMLP 529 + SE FP + + H +D+AAM LV++P + + I+T+N+FGDI+SDEAS+I GS+G+LP Sbjct: 223 KVMSEEFPQLTIQHQLIDSAAMILVQSPTKLNGIIITSNMFGDIISDEASVIPGSLGLLP 282 Query: 530 SASV 541 SAS+ Sbjct: 283 SASL 286
>LEU3_ZYGBA (Q9P3Y0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 362 Score = 147 bits (370), Expect = 2e-35 Identities = 86/184 (46%), Positives = 122/184 (66%), Gaps = 5/184 (2%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQ-LVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFG 181 GLL IR L ++ANLRP + L++ S LK + A G D +VVREL GGIYFG+ + Sbjct: 90 GLLKIRKELQLYANLRPCNFASESLLELSPLKPQHARGTDFIVVRELVGGIYFGQRK--- 146 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKL--CSVDKANVLEASMLWRKRVT 355 D G+ +++E Y+ E+ RI R+A +A + L S+DKANVL +S LWRK V Sbjct: 147 -EDDGDGVAWDSERYTKPEVQRITRMAAFLALQHNPPLPIWSLDKANVLASSRLWRKTVE 205 Query: 356 -AIASEFPDVELSHMYVDNAAMQLVRNPKQFD-TIVTNNIFGDILSDEASMITGSIGMLP 529 I +EFP + + H +D+AAM L++NP Q + I+T+N+F DI+SDEAS+I GS+G+LP Sbjct: 206 ETIKNEFPQLTVKHQLIDSAAMILIKNPTQLNGIIITSNMFEDIISDEASVIPGSLGLLP 265 Query: 530 SASV 541 SAS+ Sbjct: 266 SASL 269
>LEU3_PICST (O94114) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 373 Score = 146 bits (368), Expect = 4e-35 Identities = 88/184 (47%), Positives = 123/184 (66%), Gaps = 5/184 (2%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQ-LVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFG 181 GLL IR L ++ANLRP L++ S LK E+ +G + VVREL GGIYFG+ + Sbjct: 95 GLLKIRKELNLYANLRPCNFASDALLELSPLKSEIVKGTNFTVVRELVGGIYFGERQEQE 154 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKL--CSVDKANVLEASMLWRKRVT 355 + GE + ++TE YSVAE+ RI R+A +A + L S+DKANVL +S LWRK V Sbjct: 155 ESADGE-SAWDTEKYSVAEVTRITRMAAFMALQHNPPLPIWSLDKANVLASSRLWRKTVD 213 Query: 356 AIASE-FPDVELSHMYVDNAAMQLVRNPKQFDTIV-TNNIFGDILSDEASMITGSIGMLP 529 + E FP + + H +D+AAM LV++P + + IV T+N+FG I+SDEAS+I GS+G+LP Sbjct: 214 KVMKEEFPQLTIQHQLIDSAAMILVQSPTKLNGIVITSNMFGYIISDEASVIPGSLGLLP 273 Query: 530 SASV 541 SAS+ Sbjct: 274 SASL 277
>LEU3_CANMA (P07139) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 373 Score = 146 bits (368), Expect = 4e-35 Identities = 84/184 (45%), Positives = 124/184 (67%), Gaps = 5/184 (2%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQ-LVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFG 181 GLL IR L ++AN+RP L++ S L+ EV +G ++++VREL GGIYFG R Sbjct: 95 GLLKIRKELNLYANIRPCNFASDSLLELSPLRPEVVKGTNLIIVRELVGGIYFGD-REEQ 153 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKL--CSVDKANVLEASMLWRKRVT 355 ++T ++TE Y+V E+ RI R+A +A + L S+DKANVL +S LWR+ V Sbjct: 154 EESADKQTAWDTEKYTVDEVTRITRMAAFMALQHTPPLPIWSLDKANVLASSRLWRRTVD 213 Query: 356 AIASE-FPDVELSHMYVDNAAMQLVRNPKQFD-TIVTNNIFGDILSDEASMITGSIGMLP 529 + SE FP + + H +D+AAM L++NP + + I+T+N+FGDI+SDEAS+I GS+G+LP Sbjct: 214 KVISEEFPTLSVQHQLIDSAAMILIQNPTKLNGIIITSNMFGDIISDEASVIPGSLGLLP 273 Query: 530 SASV 541 SAS+ Sbjct: 274 SASL 277
>LEU3_CANAL (P87186) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 373 Score = 144 bits (363), Expect = 2e-34 Identities = 84/184 (45%), Positives = 121/184 (65%), Gaps = 5/184 (2%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATVLPQ-LVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFG 181 GLL IR L ++AN+RP L++ S LK EV +G ++++VREL GGIYFG+ R Sbjct: 95 GLLKIRKELNLYANIRPCNFASDSLLELSPLKAEVVKGTNLIIVRELVGGIYFGE-RQEQ 153 Query: 182 TNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKL--CSVDKANVLEASMLWRKRVT 355 + +T + Y+V E+ RI R+A +A + L S+DKANVL +S LWRK V Sbjct: 154 EESEDHQTAWYRPKYTVDEVTRITRMAAFMALQHNPPLPIWSLDKANVLASSRLWRKTVD 213 Query: 356 AIASE-FPDVELSHMYVDNAAMQLVRNPKQFD-TIVTNNIFGDILSDEASMITGSIGMLP 529 + SE FP + + H +D+AAM L++NP + I+T+N+FGDI+SDEAS+I GS+G+LP Sbjct: 214 KVISEEFPALSVQHQLIDSAAMILIQNPTKLSGIIITSNMFGDIISDEASVIPGSLGLLP 273 Query: 530 SASV 541 SAS+ Sbjct: 274 SASL 277
>LEU3_CEPAC (Q12545) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 380 Score = 138 bits (348), Expect = 9e-33 Identities = 82/191 (42%), Positives = 118/191 (61%), Gaps = 11/191 (5%) Frame = +2 Query: 2 TGLLNIRAGLGVFANLRPATVL-PQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGF 178 +GLL +R L FANLRP L P LV AS ++ V +G +VVRE GG YFG+ + Sbjct: 91 SGLLQLRQHLDAFANLRPCEFLVPSLVGASPIREHVVKGTRFIVVRENCGGAYFGEKK-- 148 Query: 179 GTNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRG--------GKLCSVDKANVLEASM 334 + E+ + +Y+ EI+R+ARV+ VAR G + S DKANVL + Sbjct: 149 ----EEEDVASDLWVYTRPEIERLARVSAAVARIMGRSEDDNQAATVWSADKANVLASGR 204 Query: 335 LWRKRVTAI-ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIV-TNNIFGDILSDEASMIT 508 LWR+ + I A EFPD+ L H D+ AM +VR+P++F+ ++ T+N FGDILSD + IT Sbjct: 205 LWRRITSDIFAKEFPDITLQHQLADSMAMLMVRDPRRFNGVIHTDNTFGDILSDISGAIT 264 Query: 509 GSIGMLPSASV 541 G++G++PSAS+ Sbjct: 265 GTLGLMPSASL 275
>LEU3B_ASPNG (P87257) 3-isopropylmalate dehydrogenase B (EC 1.1.1.85) (Beta-IPM| dehydrogenase B) (IMDH B) (3-IPM-DH B) Length = 371 Score = 126 bits (317), Expect = 3e-29 Identities = 80/189 (42%), Positives = 117/189 (61%), Gaps = 10/189 (5%) Frame = +2 Query: 5 GLLNIRAGLGVFANLRPATV-LPQLV---DASTLKREVAEGVDIMVVRELTGGIYFGKPR 172 GLL +R + ++ANLRP +V +P D S ++EV EGVD +VVRE GG YFGK Sbjct: 95 GLLQVRKAMDIYANLRPCSVDVPSREIARDFSPFRQEVIEGVDFVVVRENCGGAYFGK-- 152 Query: 173 GFGTNDKGEETGFNTEI--YSVAEIDRIARVAFEVARKRGGK--LCSVDKANVLEASMLW 340 K EE + + YS EI RIAR+A E+A + + S+DKANVL +S LW Sbjct: 153 ------KVEEENYAMDEWGYSTTEIQRIARLAAELALRHDPPWPVISLDKANVLASSRLW 206 Query: 341 RKRV-TAIASEFPDVELSHMYVDNAAMQLVRNPKQFD-TIVTNNIFGDILSDEASMITGS 514 R+ V I+ E+P V+L H D+A++ + +P+ + I+ +N FGD+LSD+A + G+ Sbjct: 207 RRVVENTISVEYPQVKLVHQLADSASLIMATDPRVLNGVILADNTFGDMLSDQAGSLIGT 266 Query: 515 IGMLPSASV 541 +G+LPSAS+ Sbjct: 267 LGVLPSASL 275
>LEU3_LEIXX (Q6AEP6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 113 bits (283), Expect = 3e-25 Identities = 69/179 (38%), Positives = 100/179 (55%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTN 187 LL +R L + NLRP T+ P + EV D +VVRE T G Y G Sbjct: 95 LLRLRFSLDHYVNLRPTTLFPGIASPLAAPGEV----DFVVVREGTEGQYVGNGGAIRPG 150 Query: 188 DKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLE-ASMLWRKRVTAIA 364 E + + ++R+ R AFE A +R KL V K NVL A LW++ V A+A Sbjct: 151 TP-HEVANEVSVNTAYGVERVVRYAFEQAGQRRKKLTLVHKTNVLTFAGSLWKRIVDALA 209 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 +E P+V + +++VD A + LV +P +FD IVT+N+FGDIL+D A+ I+G IG+ S ++ Sbjct: 210 AEHPEVAVDYLHVDAATIFLVTDPARFDVIVTDNLFGDILTDLAAAISGGIGLAASGNI 268
>LEU3_ARCFU (O29627) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 326 Score = 112 bits (279), Expect = 9e-25 Identities = 71/181 (39%), Positives = 109/181 (60%), Gaps = 2/181 (1%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTN 187 ++ +R LG FAN+RPA + + + G+DI+VVRE T +Y G GFG Sbjct: 77 IVRLRRELGTFANVRPAKAIEGI-------ECLYPGLDIVVVRENTECLYMGFEFGFG-- 127 Query: 188 DKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGK-LCSVDKANVLEASM-LWRKRVTAI 361 D E T S +RIAR AFE+A++ G K + ++ KANV++ + L+R + Sbjct: 128 DVTEAIRVITREAS----ERIARYAFELAKREGRKKVTALHKANVMKKTCGLFRDVCREV 183 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 A ++P+++ + Y+D A M LV +P +FD IVT N+FGDI+SD A+ + G +G+ PSA+V Sbjct: 184 AKDYPEIQYNDYYIDAACMYLVMDPFRFDVIVTTNMFGDIVSDLAAGLVGGLGLAPSANV 243 Query: 542 G 544 G Sbjct: 244 G 244
>LEU3_CORGL (P94631) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 340 Score = 107 bits (267), Expect = 2e-23 Identities = 69/182 (37%), Positives = 101/182 (55%), Gaps = 4/182 (2%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGF--G 181 LL +R L NLRP+ +L D +D +VVRE T G Y G G Sbjct: 84 LLKMRFALDHHVNLRPS----KLYDGVESPLRNPGKIDFVVVREGTEGAYTGNGGAIRVG 139 Query: 182 T-NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVL-EASMLWRKRVT 355 T ++ ET NT + +R+ R AFE+A+ R KL V K NVL LW++ V Sbjct: 140 TPHEIANETSVNTRYGA----ERVIRYAFELAQSRRKKLTLVHKTNVLVHGGGLWQRTVD 195 Query: 356 AIASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSA 535 +A E+P+V + + ++D A + LV +P +FD IVT+N+FGDIL+DEA ++G IG+ S Sbjct: 196 EVAKEYPEVAVDYNHIDAATIYLVTDPSRFDVIVTDNLFGDILTDEAGAVSGGIGLAASG 255 Query: 536 SV 541 ++ Sbjct: 256 NI 257
>LEU3_COREF (Q8FPV5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 340 Score = 105 bits (262), Expect = 8e-23 Identities = 67/179 (37%), Positives = 98/179 (54%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTN 187 LL +R L NLRP+ + + S LK +D +VVRE T G Y G Sbjct: 84 LLKLRFALDHHVNLRPSKLYEGV--ESPLKNPGE--IDFVVVREGTEGAYTGNGGAIRVG 139 Query: 188 DKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVL-EASMLWRKRVTAIA 364 ET T + + +R+ R AFE+A+ R L V K NVL LW++ V +A Sbjct: 140 TP-HETANETSVNTRYGAERVIRYAFELAQSRRRHLTLVHKTNVLVHGGGLWQRTVDEVA 198 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 E+P+V + + ++D A + LV +P +FD IVT+N+FGDIL+DEA I+G IG+ S ++ Sbjct: 199 REYPEVTVDYNHIDAATIYLVTDPSRFDVIVTDNLFGDILTDEAGAISGGIGLAASGNI 257
>LEU3_CORDI (Q6NHM7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 339 Score = 105 bits (261), Expect = 1e-22 Identities = 66/181 (36%), Positives = 101/181 (55%), Gaps = 3/181 (1%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTN 187 LL +R L NLRP+ + P +T +D +VVRE T G+Y G GT Sbjct: 84 LLKMRFALDHHVNLRPSKLYP----TATSPLANPGDIDFVVVREGTEGLYCGNG---GTL 136 Query: 188 DKGEETGFNTEIYSVAE--IDRIARVAFEVARKRGGKLCSVDKANVL-EASMLWRKRVTA 358 +G +E+ ++R+ R AFE A+ R L V K NVL A LW++ V Sbjct: 137 REGTPHEIASEVSQNTRYGVERVVRDAFERAQNRKKHLTLVHKTNVLVNAGGLWQRTVNE 196 Query: 359 IASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSAS 538 IA+E+P+V + + ++D A + +V +P ++D IVT+N+FGDIL+D A +TG IG+ S + Sbjct: 197 IATEYPEVTVDYNHIDAATIYMVTDPSRYDVIVTDNLFGDILTDLAGAVTGGIGLAASGN 256 Query: 539 V 541 + Sbjct: 257 I 257
>LEU3_METTH (O27441) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 329 Score = 105 bits (261), Expect = 1e-22 Identities = 66/181 (36%), Positives = 102/181 (56%), Gaps = 2/181 (1%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTN 187 ++ +R +FANLRP LP + + +D ++VRE T +Y G Sbjct: 79 IVRLRREFDLFANLRPVKSLPGVPC-------LYPDLDFVIVRENTEDLYVGD------E 125 Query: 188 DKGEETGFNTEIYSVAEIDRIARVAFEVARKRG-GKLCSVDKANVLEASM-LWRKRVTAI 361 + E I + RI++ AF+ A+K G K+ +V KANVL+ + ++R + Sbjct: 126 EYTPEGAVAKRIITRTASRRISQFAFQYAQKEGMQKVTAVHKANVLKKTDGIFRDEFYKV 185 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 ASE+P +E + YVD AM L+ P++F TIVT N+FGDILSDEA+ + G +G+ PSA++ Sbjct: 186 ASEYPQMEATDYYVDATAMYLITQPQEFQTIVTTNLFGDILSDEAAGLIGGLGLAPSANI 245 Query: 542 G 544 G Sbjct: 246 G 246
>LEU3_CORJK (Q4JUQ0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 338 Score = 104 bits (259), Expect = 2e-22 Identities = 64/181 (35%), Positives = 102/181 (56%), Gaps = 3/181 (1%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTN 187 LL +R L NLRP+ + P S+ +D +VVRE T G+Y G GT Sbjct: 84 LLPLRFKLDHAVNLRPSKLYP----GSSSPLANPGDIDFVVVREGTEGLYCGNG---GTL 136 Query: 188 DKGEETGFNTEIY--SVAEIDRIARVAFEVARKRGGKLCSVDKANVL-EASMLWRKRVTA 358 G + +E+ + ++R+ R AFE A+ R KL V K NVL A LW++ + Sbjct: 137 RAGTDYEVASEVSQNTYYGVERVVRDAFERAQSRRKKLTWVHKTNVLVNAGSLWQRAIET 196 Query: 359 IASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSAS 538 + E+P+V++ + ++D A + +V P+++D IVT+N+FGDIL+D A +TG IG+ S + Sbjct: 197 VGQEYPEVQVDYNHIDAATIYMVTKPQEYDVIVTDNLFGDILTDLAGAVTGGIGLAASGN 256 Query: 539 V 541 + Sbjct: 257 I 257
>LEU3_MYCTU (P95313) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 336 Score = 102 bits (254), Expect = 7e-22 Identities = 70/182 (38%), Positives = 100/182 (54%), Gaps = 4/182 (2%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGF--G 181 LL +R L NLRPA + P + AS L G+D +VVRE T G Y G G Sbjct: 83 LLRLRFELDHHINLRPARLYPGV--ASPLSGN--PGIDFVVVREGTEGPYTGNGGAIRVG 138 Query: 182 T-NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLE-ASMLWRKRVT 355 T N+ E NT + R+ AFE AR+R L V K NVL A LW + V Sbjct: 139 TPNEVATEVSVNTAF----GVRRVVADAFERARRRRKHLTLVHKTNVLTFAGGLWLRTVD 194 Query: 356 AIASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSA 535 + +PDVE+++ +VD A + ++ +P +FD IVT+N+FGDI++D A+ + G IG+ S Sbjct: 195 EVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDLAAAVCGGIGLAASG 254 Query: 536 SV 541 ++ Sbjct: 255 NI 256
>LEU3_MYCBO (P94929) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 336 Score = 102 bits (254), Expect = 7e-22 Identities = 70/182 (38%), Positives = 100/182 (54%), Gaps = 4/182 (2%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGF--G 181 LL +R L NLRPA + P + AS L G+D +VVRE T G Y G G Sbjct: 83 LLRLRFELDHHINLRPARLYPGV--ASPLSGN--PGIDFVVVREGTEGPYTGNGGAIRVG 138 Query: 182 T-NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLE-ASMLWRKRVT 355 T N+ E NT + R+ AFE AR+R L V K NVL A LW + V Sbjct: 139 TPNEVATEVSVNTAF----GVRRVVADAFERARRRRKHLTLVHKTNVLTLAGGLWLRTVD 194 Query: 356 AIASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSA 535 + +PDVE+++ +VD A + ++ +P +FD IVT+N+FGDI++D A+ + G IG+ S Sbjct: 195 EVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDLAAAVCGGIGLAASG 254 Query: 536 SV 541 ++ Sbjct: 255 NI 256
>LEU3_SULTO (P50455) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 336 Score = 101 bits (252), Expect = 1e-21 Identities = 69/181 (38%), Positives = 103/181 (56%), Gaps = 2/181 (1%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEG-VDIMVVRELTGGIYFGKPRGFGT 184 ++ +R ++AN+RPA +P + + G VDI++VRE T +Y +GF Sbjct: 81 VVKLRQIYDMYANIRPAKSIPGI--------DTKYGNVDILIVRENTEDLY----KGF-E 127 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLEASM-LWRKRVTAI 361 + + +I + +RIA+V A +R K+ V KANV+ + L+ + ++ Sbjct: 128 HIVSDGVAVGMKIITRFASERIAKVGLNFALRRRKKVTCVHKANVMRITDGLFAEACRSV 187 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 VE S MYVD AA LVRNP+ FD IVT N++GDILSDEAS I GS+G+ PSA++ Sbjct: 188 LKG--KVEYSEMYVDAAAANLVRNPQMFDVIVTENVYGDILSDEASQIAGSLGIAPSANI 245 Query: 542 G 544 G Sbjct: 246 G 246
>LEU3_BIFLO (Q8G500) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 343 Score = 101 bits (251), Expect = 2e-21 Identities = 61/179 (34%), Positives = 95/179 (53%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTN 187 LL +R L + NLRP+ +L T +D +VVRE T G+Y G N Sbjct: 90 LLKLRFDLDQYVNLRPS----KLYKGVTSPLANPGDIDFVVVREGTEGLYCGAGGAVRRN 145 Query: 188 DKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVL-EASMLWRKRVTAIA 364 +E I + ++R+ R AF++A KR + V K NVL A +W++ V + Sbjct: 146 TP-QEVATEVSINTAYGVERVVRYAFKLAMKRKKHVTLVHKKNVLVNAGDMWQRIVDKVG 204 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 E+P+V + ++D A + LV +P +FD I+T+N+FGDIL+DEA + G +G S + Sbjct: 205 EEYPEVTHDYQHIDAATIFLVSDPSRFDVILTDNLFGDILTDEAGSVVGGVGYSASGCI 263
>LEU3_THEFY (Q47SB4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 354 Score = 100 bits (250), Expect = 2e-21 Identities = 64/182 (35%), Positives = 99/182 (54%), Gaps = 4/182 (2%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTN 187 LL +R + NLRP + P + + L E +D++VVRE T G Y G G Sbjct: 92 LLRLRFNFSHYVNLRPVRLYPGVT--TPLAGVAPEDIDMLVVREGTEGPYAGMG---GVL 146 Query: 188 DKG--EETGFNTEIYSVAEIDRIARVAFEVARKRG-GKLCSVDKANVLE-ASMLWRKRVT 355 KG E + + ++R+ R AF A +R KL V K NVL A LW++ V Sbjct: 147 RKGTPHEIATQDSVNTRLGVERVVRYAFAKAAERPCHKLTLVHKDNVLTYAGELWQRVVR 206 Query: 356 AIASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSA 535 + +E+P VE+ +++VD A M V P++FD +VT+N+FGDI++D + + G IG+ S Sbjct: 207 EVGAEYPQVEVDYLHVDAATMFFVTQPRRFDVVVTDNLFGDIITDLGAAVAGGIGLAASG 266 Query: 536 SV 541 ++ Sbjct: 267 NI 268
>LEU3_STRCO (O86504) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 347 Score = 99.0 bits (245), Expect = 8e-21 Identities = 68/182 (37%), Positives = 101/182 (55%), Gaps = 4/182 (2%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTN 187 LL +R NLRP+ +LP + + E+ D +VVRE T G Y G GT Sbjct: 90 LLKLRFAFDHHVNLRPSKLLPGVATPLAGQPEI----DFVVVREGTEGPYTGNG---GTI 142 Query: 188 DKGEETGFNTEIY--SVAEIDRIARVAFEVARKRGGK-LCSVDKANVLE-ASMLWRKRVT 355 KG E TE+ + ++R+ R AF A+ R K L V K NVL A LW Sbjct: 143 RKGTEHEVATEVSVNTAYGVERVVRDAFARAQARPRKKLTLVHKNNVLTFAGHLWTNIFN 202 Query: 356 AIASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSA 535 +A+E+P+V +++VD A + LV +P +FD IVT+N+FGDI++D A+ ++G IG+ S Sbjct: 203 KVAAEYPEVTTDYLHVDAATIFLVTDPARFDVIVTDNLFGDIITDLAAAVSGGIGVAASG 262 Query: 536 SV 541 ++ Sbjct: 263 NI 264
>TTUC_ECOLI (P76251) Probable tartrate dehydrogenase/decarboxylase (EC| 1.1.1.93) (EC 4.1.1.73) (TDH) (D-malate dehydrogenase [decarboxylating]) (EC 1.1.1.83) Length = 361 Score = 97.8 bits (242), Expect = 2e-20 Identities = 65/181 (35%), Positives = 95/181 (52%), Gaps = 3/181 (1%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTN 187 LL R + NLRP + P + L + +D VVRE T G Y G N Sbjct: 93 LLKFRREFDQYVNLRPVRLFPGV--PCPLAGKQPGDIDFYVVRENTEGEY--SSLGGRVN 148 Query: 188 DKGE-ETGFNTEIYSVAEIDRIARVAFEVARKRGGK-LCSVDKANVLEASM-LWRKRVTA 358 + E E +++ +DRI R AFE+A+ R K L S K+N L SM W +RV A Sbjct: 149 EGTEHEVVIQESVFTRRGVDRILRYAFELAQSRPRKTLTSATKSNGLAISMPYWDERVEA 208 Query: 359 IASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSAS 538 +A +P++ ++D + V P++FD +V +N+FGDILSD TG+IG+ PSA+ Sbjct: 209 MAENYPEIRWDKQHIDILCARFVMQPERFDVVVASNLFGDILSDLGPACTGTIGIAPSAN 268 Query: 539 V 541 + Sbjct: 269 L 269
>LEU3_STRAW (Q82JN6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 347 Score = 97.4 bits (241), Expect = 2e-20 Identities = 69/182 (37%), Positives = 97/182 (53%), Gaps = 4/182 (2%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTN 187 LL +R NLRP+ +LP + + E+ D +VVRE T G Y G GT Sbjct: 90 LLKLRFAFDHHVNLRPSKLLPGVETPLAGQPEI----DFVVVREGTEGPYTGNG---GTI 142 Query: 188 DKGEETGFNTEIY--SVAEIDRIARVAFEVARKRGGK-LCSVDKANVL-EASMLWRKRVT 355 G TE+ + I+R+ R A+ A+ R K L V K NVL A LW Sbjct: 143 RTGTPHAVATEVSLNTAFGIERVVRDAYARAQARPRKKLALVHKNNVLVHAGHLWTDIFN 202 Query: 356 AIASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSA 535 + EFPDV +M+VD A + LV P++FD IVT+N+FGDI++D A+ I+G IG+ S Sbjct: 203 KVGEEFPDVTTEYMHVDAATIYLVTQPERFDVIVTDNLFGDIITDLAAAISGGIGVAASG 262 Query: 536 SV 541 ++ Sbjct: 263 NI 264
>LEU3_MYCLE (O33117) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 336 Score = 97.4 bits (241), Expect = 2e-20 Identities = 67/182 (36%), Positives = 97/182 (53%), Gaps = 4/182 (2%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGF--G 181 LL +R L NLRPA + P + K ++ D +VVRE T G Y G G Sbjct: 83 LLRLRFELDHHINLRPARLYPGVNSLLAGKPDI----DFVVVREGTEGPYTGTGGAIRVG 138 Query: 182 T-NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLE-ASMLWRKRVT 355 T N+ E NT + R+ + AFE AR+R L V K NVL A LW + V Sbjct: 139 TPNEVATEVSVNTAF----GVRRVVQDAFERARQRRKHLTLVHKNNVLTYAGTLWCRIVQ 194 Query: 356 AIASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSA 535 + ++PDVE+ + ++D A + LV P +FD IVT+N+FGDI++D A+ + G I + S Sbjct: 195 EVGEKYPDVEVVYQHIDAATIYLVTEPSRFDVIVTDNLFGDIITDLAAAVCGGIALAASG 254 Query: 536 SV 541 ++ Sbjct: 255 NI 256
>IDH_THET8 (P33197) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 496 Score = 96.7 bits (239), Expect = 4e-20 Identities = 62/180 (34%), Positives = 96/180 (53%), Gaps = 2/180 (1%) Frame = +2 Query: 11 LNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTND 190 + +R +AN+RP P + G+D++VVRE +Y G + Sbjct: 101 VTLRKLFETYANVRPVREFPNVPTPYA-----GRGIDLVVVRENVEDLYAGIE-----HM 150 Query: 191 KGEETGFNTEIYSVAEIDRIARVAFEVARKRGGK-LCSVDKANVLEASMLWRKRV-TAIA 364 + ++ S ++I R AFE+AR G K + K+N+++ + KR +A Sbjct: 151 QTPSVAQTLKLISWKGSEKIVRFAFELARAEGRKKVHCATKSNIMKLAEGTLKRAFEQVA 210 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASVG 544 E+PD+E H+ VDNAA QLV+ P+QF+ IVT N+ GDILSD S + G +G PSA++G Sbjct: 211 QEYPDIEAVHIIVDNAAHQLVKRPEQFEVIVTTNMNGDILSDLTSGLIGGLGFAPSANIG 270
>LEU3_NOCFA (Q5YRX2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 335 Score = 96.3 bits (238), Expect = 5e-20 Identities = 64/182 (35%), Positives = 95/182 (52%), Gaps = 4/182 (2%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTN 187 LL R L NLRP+ +L A +D +VVRE T G Y G Sbjct: 83 LLRTRFELDHHVNLRPS----RLFTGVRSPLAGAPDIDFVVVREGTEGPYTGTGGAIRVR 138 Query: 188 DKGE---ETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLE-ASMLWRKRVT 355 E E NT I+R+ R AF A+ R L V K NVL A LW++ V Sbjct: 139 TPHEVATEVSTNTRF----GIERVVRYAFAKAQARRKHLTLVHKTNVLTFAGSLWQRTVD 194 Query: 356 AIASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSA 535 + +EFP+V +++ ++D A + +V +P +FD IVT+N+FGDI++D A+ ++G IG+ S Sbjct: 195 EVGAEFPEVTVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITDLAAAVSGGIGLAASG 254 Query: 536 SV 541 ++ Sbjct: 255 NI 256
>LEU3_SULSO (Q9UXB2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 336 Score = 96.3 bits (238), Expect = 5e-20 Identities = 68/183 (37%), Positives = 96/183 (52%), Gaps = 4/183 (2%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTN 187 ++ +R ++AN+RPA LP + + VD+++VRE T +Y +GF Sbjct: 82 VVKLRQMYDMYANIRPAKSLPNV-------QSKYPNVDLVIVRENTEDLY----KGF--- 127 Query: 188 DKGEETGFNTEIYSVAEI--DRIARVAFEVARKRGGKLCSVDKANVLEASMLWRKRVTAI 361 + TG I E RI VA A R K+ V KANV+ + ++ Sbjct: 128 EFVTSTGVTIAIKVTTEFASKRIVNVALNYALMRRRKVTCVHKANVMRVT---DGLFASV 184 Query: 362 ASEF--PDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSA 535 E V MYVD AA LVR+P +FD IVT+N++GDILSDEAS I GS+G+ PSA Sbjct: 185 CREILKGKVNFEEMYVDAAAANLVRDPTRFDVIVTSNVYGDILSDEASQIAGSLGLAPSA 244 Query: 536 SVG 544 ++G Sbjct: 245 NIG 247
>AKSF_METJA (Q58991) Threo-isocitrate dehydrogenase [NAD] (EC 1.1.1.-)| Length = 347 Score = 95.9 bits (237), Expect = 6e-20 Identities = 62/186 (33%), Positives = 100/186 (53%), Gaps = 7/186 (3%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPAT------VLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKP 169 ++ +R ++AN+RP ++ ++ D L A+ +DI+++RE T +Y G+ Sbjct: 83 IITLRKMFHLYANVRPINNFGIGQLIGKIADYEFLN---AKNIDIVIIRENTEDLYVGRE 139 Query: 170 RGFGTNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCS-VDKANVLEASMLWRK 346 R +T + + +RI R AFE A K K S + KANVL + Sbjct: 140 R------LENDTAIAERVITRKGSERIIRFAFEYAIKNNRKKVSCIHKANVLRITDGLFL 193 Query: 347 RVTAIASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGML 526 V + ++E VD+ AM L+++P++FD IVT N+FGDILSDEAS + G +G+ Sbjct: 194 EVFNEIKKHYNIEADDYLVDSTAMNLIKHPEKFDVIVTTNMFGDILSDEASALIGGLGLA 253 Query: 527 PSASVG 544 PSA++G Sbjct: 254 PSANIG 259
>LEU3_MYCPA (Q73VI1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 336 Score = 95.1 bits (235), Expect = 1e-19 Identities = 66/182 (36%), Positives = 99/182 (54%), Gaps = 4/182 (2%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGF--G 181 LL +R L NLRP + P + +S L +D +VVRE T G Y G G Sbjct: 83 LLRLRFELDHHINLRPGRLYPGV--SSPLAGN--PDIDFVVVREGTEGPYTGTGGAIRVG 138 Query: 182 T-NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKANVLE-ASMLWRKRVT 355 T N+ E NT + R+ AFE AR+R L V K NVL A LW + V Sbjct: 139 TPNEVATEVSQNTAF----GVRRVVVDAFERARRRRKHLTLVHKTNVLTFAGKLWSRIVA 194 Query: 356 AIASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSA 535 + ++PDVE+++ ++D A + +V +P +FD IVT+N+FGDI++D ++ + G IG+ S Sbjct: 195 EVGRDYPDVEVAYQHIDAATIFMVTDPGRFDVIVTDNLFGDIITDLSAAVCGGIGLAASG 254 Query: 536 SV 541 ++ Sbjct: 255 NI 256
>TTUC2_AGRVI (P70787) Probable tartrate dehydrogenase/decarboxylase ttuC (EC| 1.1.1.93) (EC 4.1.1.73) (TDH) (D-malate dehydrogenase [decarboxylating]) (EC 1.1.1.83) Length = 364 Score = 93.6 bits (231), Expect = 3e-19 Identities = 64/181 (35%), Positives = 95/181 (52%), Gaps = 4/181 (2%) Frame = +2 Query: 11 LNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTND 190 L I G +AN+RP VLP + L+ +D ++VRE + G Y G G Sbjct: 92 LPICQGFDQYANVRPTKVLPGITPP--LRNCGPGDLDWVIVRENSEGEYSGHG---GRAH 146 Query: 191 KG--EETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSV-DKANVLEASM-LWRKRVTA 358 KG EE G I++ + RI R AF++A+ R KL +V K+N M +W + Sbjct: 147 KGLPEEVGTEVAIFTRVGVTRIMRYAFKLAQARPRKLLTVVTKSNAQRHGMVMWDEIAAE 206 Query: 359 IASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSAS 538 ++ EFPDV M VD +++ P+ DTIV N+ DILSD A + GS+G+ P+A+ Sbjct: 207 VSKEFPDVTWDKMLVDAMTVRMTLKPQSLDTIVATNLHADILSDLAGALAGSLGVAPTAN 266 Query: 539 V 541 + Sbjct: 267 I 267
>TTUC1_AGRVI (Q44471) Probable tartrate dehydrogenase/decarboxylase ttuC (EC| 1.1.1.93) (EC 4.1.1.73) (TDH) (D-malate dehydrogenase [decarboxylating]) (EC 1.1.1.83) Length = 364 Score = 93.6 bits (231), Expect = 3e-19 Identities = 62/179 (34%), Positives = 94/179 (52%), Gaps = 2/179 (1%) Frame = +2 Query: 11 LNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTND 190 L I G +AN+RP +LP + L+ +D ++VRE + G Y G G Sbjct: 92 LPICQGFDQYANVRPTKILPGITPP--LRNCGPGDLDWVIVRENSEGEYSGHG-GRAHRG 148 Query: 191 KGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSV-DKANVLEASM-LWRKRVTAIA 364 EE G I++ + RI R AF++A+ R KL +V K+N M +W + +A Sbjct: 149 LPEEVGTEVAIFTRVGVTRIMRYAFKLAQARPRKLLTVVTKSNAQRHGMVMWDEIAAEVA 208 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 +EFPDV M VD +++ P+ DTIV N+ DILSD A + GS+G+ P+A++ Sbjct: 209 TEFPDVTWDKMLVDAMTVRMTLKPETLDTIVATNLHADILSDLAGALAGSLGVAPTANI 267
>TTUC5_AGRVI (O34295) Probable tartrate dehydrogenase/decarboxylase ttuC' (EC| 1.1.1.93) (EC 4.1.1.73) (TDH) (D-malate dehydrogenase [decarboxylating]) (EC 1.1.1.83) Length = 358 Score = 93.6 bits (231), Expect = 3e-19 Identities = 62/179 (34%), Positives = 94/179 (52%), Gaps = 2/179 (1%) Frame = +2 Query: 11 LNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTND 190 L I G +AN+RP +LP + L+ +D ++VRE + G Y G G Sbjct: 92 LPICQGFDQYANVRPTKILPGITPP--LRNCGPGDLDWVIVRENSEGEYSGHG-GRAHRG 148 Query: 191 KGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSV-DKANVLEASM-LWRKRVTAIA 364 EE G I++ + RI R AF++A+ R KL +V K+N M +W + +A Sbjct: 149 LPEEVGTEVAIFTRVGVTRIMRYAFKLAQARPRKLLTVVTKSNAQRHGMVMWDEIAAEVA 208 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 +EFPDV M VD +++ P+ DTIV N+ DILSD A + GS+G+ P+A++ Sbjct: 209 TEFPDVTWDKMLVDAMTVRMTLKPETLDTIVATNLHADILSDLAGALAGSLGVAPTANI 267
>TTUC4_AGRVI (P70792) Probable tartrate dehydrogenase/decarboxylase ttuC' (EC| 1.1.1.93) (EC 4.1.1.73) (TDH) (D-malate dehydrogenase [decarboxylating]) (EC 1.1.1.83) Length = 358 Score = 93.6 bits (231), Expect = 3e-19 Identities = 64/181 (35%), Positives = 95/181 (52%), Gaps = 4/181 (2%) Frame = +2 Query: 11 LNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTND 190 L I G +AN+RP VLP + L+ +D ++VRE + G Y G G Sbjct: 92 LPICQGFDQYANVRPTKVLPGITPP--LRNCGPGDLDWVIVRENSEGEYSGHG---GRAH 146 Query: 191 KG--EETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSV-DKANVLEASM-LWRKRVTA 358 KG EE G I++ + RI R AF++A+ R KL +V K+N M +W + Sbjct: 147 KGLPEEVGTEVAIFTRVGVTRIMRYAFKLAQARPRKLLTVVTKSNAQRHGMVMWDEIAAE 206 Query: 359 IASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSAS 538 ++ EFPDV M VD +++ P+ DTIV N+ DILSD A + GS+G+ P+A+ Sbjct: 207 VSKEFPDVTWDKMLVDAMTVRMTLKPQSLDTIVATNLHADILSDLAGALAGSLGVAPTAN 266 Query: 539 V 541 + Sbjct: 267 I 267
>TTUC3_AGRVI (O34296) Probable tartrate dehydrogenase/decarboxylase ttuC' (EC| 1.1.1.93) (EC 4.1.1.73) (TDH) (D-malate dehydrogenase [decarboxylating]) (EC 1.1.1.83) Length = 358 Score = 93.6 bits (231), Expect = 3e-19 Identities = 62/179 (34%), Positives = 94/179 (52%), Gaps = 2/179 (1%) Frame = +2 Query: 11 LNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTND 190 L I G +AN+RP +LP + L+ +D ++VRE + G Y G G Sbjct: 92 LPICQGFDQYANVRPTKILPGITPP--LRNCGPGDLDWVIVRENSEGEYSGHG-GRAHRG 148 Query: 191 KGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSV-DKANVLEASM-LWRKRVTAIA 364 EE G I++ + RI R AF++A+ R KL +V K+N M +W + +A Sbjct: 149 LPEEVGTEVAIFTRVGVTRIMRYAFKLAQARPRKLLTVVTKSNAQRHGMVMWDEIAAEVA 208 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 +EFPDV M VD +++ P+ DTIV N+ DILSD A + GS+G+ P+A++ Sbjct: 209 TEFPDVTWDKMLVDAMTVRMTLKPETLDTIVATNLHADILSDLAGALAGSLGVAPTANI 267
>LEU3_METJA (Q58130) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM| dehydrogenase) (IMDH) (3-IPM-DH) Length = 333 Score = 93.2 bits (230), Expect = 4e-19 Identities = 61/185 (32%), Positives = 99/185 (53%), Gaps = 6/185 (3%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTN 187 ++ +R L +AN+RP V A + + +D ++VRE T G+Y G Sbjct: 77 IVKLRHILDTYANIRP-------VKAYKGVKCLRPDIDYVIVRENTEGLYKGIEA----- 124 Query: 188 DKGEETGFNTEIYSVAEIDRIARVAFEVARKRG-----GKLCSVDKANVLEASM-LWRKR 349 + E T + + +RI R AF +AR+R GK+ KANVL+ + L++K Sbjct: 125 EIDEGITIATRVITEKACERIFRFAFNLARERKKMGKEGKVTCAHKANVLKLTDGLFKKI 184 Query: 350 VTAIASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLP 529 +A E+ D++ Y+D M ++ P+ FD +VT+N+FGDILSD A+ G +G+ P Sbjct: 185 FYKVAEEYDDIKAEDYYIDAMNMYIITKPQVFDVVVTSNLFGDILSDGAAGTVGGLGLAP 244 Query: 530 SASVG 544 SA++G Sbjct: 245 SANIG 249
>TTUC_PSEPU (Q51945) Tartrate dehydrogenase/decarboxylase (EC 1.1.1.93) (EC| 4.1.1.73) (TDH) (D-malate dehydrogenase [decarboxylating]) (EC 1.1.1.83) Length = 364 Score = 91.3 bits (225), Expect = 2e-18 Identities = 62/181 (34%), Positives = 95/181 (52%), Gaps = 3/181 (1%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTN 187 LL R + N+RP + P V + R+V + +D +VVRE T G Y G Sbjct: 93 LLKFRREFDQYVNIRPVRLFPG-VPCALANRKVGD-IDFVVVRENTEGEY-SSLGGIMFE 149 Query: 188 DKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGK-LCSVDKANVLEASM-LWRKRVTAI 361 + E I++ +DRI + AF++A KR K + S K+N + SM W KR A+ Sbjct: 150 NTENEIVIQESIFTRRGVDRILKYAFDLAEKRERKHVTSATKSNGMAISMPYWDKRTEAM 209 Query: 362 ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVT-NNIFGDILSDEASMITGSIGMLPSAS 538 A+ +P V ++D + V P++FD +V +N+FGDILSD G+IG+ PSA+ Sbjct: 210 AAHYPHVSWDKQHIDILCARFVLQPERFDVVVVASNLFGDILSDLGPACAGTIGIAPSAN 269 Query: 539 V 541 + Sbjct: 270 L 270
>IDH1_KLULA (O94229) Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial| precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 361 Score = 91.3 bits (225), Expect = 2e-18 Identities = 62/185 (33%), Positives = 104/185 (56%), Gaps = 5/185 (2%) Frame = +2 Query: 5 GLLNI--RAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGF 178 G LN+ R L +FAN+ +P + + +D++++RE T G Y G Sbjct: 103 GSLNVALRKQLDIFANVALFKSIPGV-------KTRLNNIDMVIIRENTEGEYSGLE--- 152 Query: 179 GTNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGK-LCSVDKANVLE-ASMLWRKRV 352 ++ + +I + A+ +RIAR AF+ A K K +C+V KAN+++ L+R V Sbjct: 153 --HESVPGVVESLKIMTRAKSERIARFAFDFALKNNRKSVCAVHKANIMKLGDGLFRNTV 210 Query: 353 TAI-ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLP 529 I A+E+P++++ ++ VDNA+MQ V P QFD +VT N++G IL + S + G G++P Sbjct: 211 NEIGANEYPELDVKNIIVDNASMQAVAKPHQFDVLVTPNLYGSILGNIGSALIGGPGLVP 270 Query: 530 SASVG 544 A+ G Sbjct: 271 GANFG 275
>LYS12_YEAST (P40495) Homoisocitrate dehydrogenase, mitochondrial precursor (EC| 1.1.1.87) Length = 371 Score = 83.2 bits (204), Expect = 4e-16 Identities = 57/189 (30%), Positives = 98/189 (51%), Gaps = 10/189 (5%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTN 187 ++ +R +G+FAN+RP +++ E + +D+++VRE T +Y + + Sbjct: 110 IVALRREMGLFANVRPV---------KSVEGEKGKPIDMVIVRENTEDLYIKIEKTYIDK 160 Query: 188 DKGEETGFNTEIYSVAEIDRIARVAFEVARKR-----GGKLCSVDKANVLEASM-LWRKR 349 G T+ S RIA +A ++A KR L K+NVL S L+R+ Sbjct: 161 ATGTRVADATKRISEIATRRIATIALDIALKRLQTRGQATLTVTHKSNVLSQSDGLFREI 220 Query: 350 VTAI----ASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSI 517 + ++ ++ + VD+ +L R P+ FD IV N++GDILSD A+ + GS+ Sbjct: 221 CKEVYESNKDKYGQIKYNEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSL 280 Query: 518 GMLPSASVG 544 G++PSA+VG Sbjct: 281 GVVPSANVG 289
>LEU3_SOLTU (P29696) 3-isopropylmalate dehydrogenase, chloroplast precursor (EC| 1.1.1.85) (Beta-IPM dehydrogenase) (IMDH) (3-IPM-DH) Length = 357 Score = 82.4 bits (202), Expect = 7e-16 Identities = 53/180 (29%), Positives = 94/180 (52%), Gaps = 2/180 (1%) Frame = +2 Query: 11 LNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTND 190 L +R L ++AN+RP LP + + V+++ +RE T G Y G Sbjct: 117 LTLRKELNLYANVRPCYSLPGY-------KTRYDDVNLITIRENTEGEYSGLEHQV-VRG 168 Query: 191 KGEETGFNTEIYSVAEIDRIARVAFEVARKRGG-KLCSVDKANVLEASM-LWRKRVTAIA 364 E T S+ R+A AF A+ G ++ ++ KAN+++ + L+ K +A Sbjct: 169 VVESLKIITRQASL----RVAEYAFHYAKTHGRERVSAIHKANIMQKTDGLFLKCCREVA 224 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASVG 544 ++P+++ + +DN M LV+NP FD +V N++GDI+SD + + G +G+ PS ++G Sbjct: 225 EKYPEIKYEEVVIDNCCMMLVKNPALFDVLVMPNLYGDIISDLCAGLIGGLGLTPSCNIG 284
>TTUC_BACSU (P42958) Probable tartrate dehydrogenase/decarboxylase (EC| 1.1.1.93) (EC 4.1.1.73) (TDH) (D-malate dehydrogenase [decarboxylating]) (EC 1.1.1.83) Length = 354 Score = 81.6 bits (200), Expect = 1e-15 Identities = 53/179 (29%), Positives = 89/179 (49%), Gaps = 1/179 (0%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTN 187 LL IR L + N+RPA + + + D +V+RE + G Y G + Sbjct: 94 LLKIRRELELSINMRPAKQMAGITSPLLHPNDF----DFVVIRENSEGEY--SEVGGRIH 147 Query: 188 DKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSVDKAN-VLEASMLWRKRVTAIA 364 +E +++ +R+ R AFE+A+KR + S K+N + A W + A Sbjct: 148 RGDDEIAIQNAVFTRKATERVMRFAFELAKKRRSHVTSATKSNGIYHAMPFWDEVFQQTA 207 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASV 541 +++ +E S ++D A V P+ FD IV + +FGDIL+D +S + SIG+ P A++ Sbjct: 208 ADYSGIETSSQHIDALAAFFVTRPETFDVIVASKLFGDILTDISSSLMESIGIAPPANI 266
>IDH3B_HUMAN (O43837) Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial| precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 385 Score = 81.3 bits (199), Expect = 2e-15 Identities = 53/178 (29%), Positives = 94/178 (52%), Gaps = 2/178 (1%) Frame = +2 Query: 11 LNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTND 190 + +R L +FAN+ LP + +D++++RE T G Y ++ Sbjct: 130 MRLRRKLDLFANVVHVKSLPGYMTRHN-------NLDLVIIREQTEGEYSSLE-----HE 177 Query: 191 KGEETGFNTEIYSVAEIDRIARVAFEVARKRG-GKLCSVDKANVLE-ASMLWRKRVTAIA 364 +I + A+ RIA+ AF+ A K+G GK+ +V KAN+++ L+ + +A Sbjct: 178 SARGVIECLKIVTRAKSQRIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVA 237 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSAS 538 +P ++ M +DN MQLV+NP QFD +V N++G+I+ + A+ + G G++P S Sbjct: 238 ELYPKIKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGES 295
>IDH_RICCN (Q92IR7) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 483 Score = 81.3 bits (199), Expect = 2e-15 Identities = 57/180 (31%), Positives = 96/180 (53%), Gaps = 2/180 (1%) Frame = +2 Query: 11 LNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTND 190 + IR L +FAN+RPA V R + +++ ++RE +Y G T++ Sbjct: 86 VTIRKTLQLFANIRPA------VSLHPFTRTLHPNLNLTIIRENEEDLYAGIEYR-QTHN 138 Query: 191 KGEETGFNTEIYSVAEIDRIARVAFEVARKRGGK-LCSVDKANVLEASM-LWRKRVTAIA 364 E + ++ S ++I R AFE A K K + + K N+++ S + K IA Sbjct: 139 MYE----SMKLISHTGCEKIIRYAFEYAVKNNRKKVMCLSKDNIMKFSDGVLHKVFNEIA 194 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASVG 544 E+P + +H +D +L P+ FD IVT+N++GDI+SD A+ I+GS+G+ SA++G Sbjct: 195 KEYPQINNAHYIIDIGTARLATKPEIFDVIVTSNLYGDIISDVAAEISGSVGLAGSANIG 254
>IDH3A_DROME (Q9VWH4) Probable isocitrate dehydrogenase [NAD] subunit alpha,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 377 Score = 80.5 bits (197), Expect = 3e-15 Identities = 50/180 (27%), Positives = 95/180 (52%), Gaps = 2/180 (1%) Frame = +2 Query: 11 LNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTND 190 L +R ++AN+RP L + + + VD++ +RE T G Y G ++ Sbjct: 128 LALRKEFNLYANVRPCRSLEGY-------KTLYDDVDVVTIRENTEGEYSGIE-----HE 175 Query: 191 KGEETGFNTEIYSVAEIDRIARVAFEVARKRGGKLCSV-DKANVLEASM-LWRKRVTAIA 364 + + ++ + R+A AF+ A+ K +V KAN++ S L+ + V +A Sbjct: 176 IVDGVVQSIKLITEEASKRVAEYAFQYAKNNNRKKVTVVHKANIMRMSDGLFLRCVRDMA 235 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASVG 544 +FP+++ Y+D + +V+NP ++D +V N++GDILSD + + G +G+ PS ++G Sbjct: 236 QKFPEIQFEEKYLDTVCLNMVQNPGKYDVLVMPNLYGDILSDMCAGLVGGLGLTPSGNMG 295
>IDH_RICTY (Q68XA5) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 483 Score = 80.1 bits (196), Expect = 4e-15 Identities = 56/180 (31%), Positives = 96/180 (53%), Gaps = 2/180 (1%) Frame = +2 Query: 11 LNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTND 190 + IR L +FAN+RPA V R + +++ ++RE +Y G T++ Sbjct: 86 VTIRKTLQLFANIRPA------VSFHPFTRTLHPNLNLTIIRENEEDLYSGIEYR-QTHN 138 Query: 191 KGEETGFNTEIYSVAEIDRIARVAFEVARKRGGK-LCSVDKANVLEASM-LWRKRVTAIA 364 E + ++ S +I R AFE A K K + + K N+++ S ++ + IA Sbjct: 139 MYE----SLKLISHTGCKKIIRYAFEYAVKNNRKKVTCLSKDNIMKFSDGIFHRVFNEIA 194 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASVG 544 E+P ++ H +D +L P+ FD IVT+N++GDI+SD A+ I+GS+G+ SA++G Sbjct: 195 KEYPQIDNEHYIIDIGTAKLATTPEIFDIIVTSNLYGDIISDVAAEISGSVGLAGSANIG 254
>IDH3B_CAEEL (Q93353) Probable isocitrate dehydrogenase [NAD] subunit beta,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 379 Score = 80.1 bits (196), Expect = 4e-15 Identities = 54/182 (29%), Positives = 94/182 (51%), Gaps = 4/182 (2%) Frame = +2 Query: 11 LNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGF--GT 184 + +R L +FAN+ L +K + +D ++VRE T G Y G Sbjct: 126 MRLRRSLDLFANVVHIKTL------DGIKTRHGKQLDFVIVREQTEGEYSSLEHELVPGV 179 Query: 185 NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGK-LCSVDKANVLE-ASMLWRKRVTA 358 + +I + + +RIA+ AF+ A K G K + +V KAN+++ L+ + Sbjct: 180 IEC-------LKISTRTKAERIAKFAFDYATKTGRKKVTAVHKANIMKLGDGLFLRTCEG 232 Query: 359 IASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSAS 538 +A ++P ++ M +DN MQLV P+QFD +V N++G+I+ + A+ + G G++P S Sbjct: 233 VAKQYPKIQFESMIIDNTCMQLVSKPEQFDVMVMPNLYGNIIDNLAAGLVGGAGVVPGQS 292 Query: 539 VG 544 VG Sbjct: 293 VG 294
>IDH3A_CAEEL (Q93714) Probable isocitrate dehydrogenase [NAD] subunit alpha,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 358 Score = 80.1 bits (196), Expect = 4e-15 Identities = 54/182 (29%), Positives = 91/182 (50%), Gaps = 4/182 (2%) Frame = +2 Query: 11 LNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTND 190 L +R ++AN+RP L + + + VD++ +RE T G Y G Sbjct: 105 LAVRKEFSLYANVRPCRSLEG-------HKTLYDNVDVVTIRENTEGEYSGIEHEI---- 153 Query: 191 KGEETGFNTEIYSVAEID--RIARVAFEVARKRGGKLCS-VDKANVLEASM-LWRKRVTA 358 G I + E +A AFE AR+ G K+ + V KAN++ S L+ Sbjct: 154 ---VPGVVQSIKLITETASRNVASFAFEYARQNGRKVVTAVHKANIMRQSDGLFLSICRE 210 Query: 359 IASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSAS 538 A+ +PD++ Y+D + +V++P Q+D +V N++GDILSD + + G +G+ PS + Sbjct: 211 QAALYPDIKFKEAYLDTVCLNMVQDPSQYDVLVMPNLYGDILSDLCAGLVGGLGVTPSGN 270 Query: 539 VG 544 +G Sbjct: 271 IG 272
>IDH3B_BOVIN (O77784) Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial| precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) (NAD(+)-isocitrate dehydrogenase subunit 1) (IDH1) Length = 385 Score = 79.3 bits (194), Expect = 6e-15 Identities = 52/178 (29%), Positives = 93/178 (52%), Gaps = 2/178 (1%) Frame = +2 Query: 11 LNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTND 190 + +R L +FAN+ LP + +D++++RE T G Y ++ Sbjct: 130 MRLRRKLDLFANVVHVKSLPGY-------KTRHNNLDLVIIREQTEGEYSSLE-----HE 177 Query: 191 KGEETGFNTEIYSVAEIDRIARVAFEVARKRG-GKLCSVDKANVLE-ASMLWRKRVTAIA 364 +I + + RIA+ AF+ A K+G GK+ +V KAN+++ L+ + +A Sbjct: 178 SARGVIECLKIVTRTKSQRIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVA 237 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSAS 538 +P ++ M +DN MQLV+NP QFD +V N++G+I+ + A+ + G G++P S Sbjct: 238 ELYPKIKFEKMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGES 295
>IDH3B_MACFA (Q28479) Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial| precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) (Fragment) Length = 381 Score = 79.0 bits (193), Expect = 8e-15 Identities = 52/178 (29%), Positives = 93/178 (52%), Gaps = 2/178 (1%) Frame = +2 Query: 11 LNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTND 190 + +R L +FAN+ LP + +D++++RE T G Y ++ Sbjct: 128 MRLRRKLDLFANVVHVKSLPGYMTRHN-------NLDLVIIREQTEGEYSSLE-----HE 175 Query: 191 KGEETGFNTEIYSVAEIDRIARVAFEVARKRG-GKLCSVDKANVLE-ASMLWRKRVTAIA 364 +I + A+ RIA+ AF+ A K+G K+ +V KAN+++ L+ + +A Sbjct: 176 SARGVIECLKIVTRAKSQRIAKFAFDYATKKGRSKVTAVHKANIMKLGDGLFLQCCEEVA 235 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSAS 538 +P ++ M +DN MQLV+NP QFD +V N++G+I+ + A+ + G G++P S Sbjct: 236 ELYPKIKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGES 293
>IDH1_AJECA (O13302) Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial| precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 388 Score = 78.6 bits (192), Expect = 1e-14 Identities = 48/147 (32%), Positives = 81/147 (55%), Gaps = 2/147 (1%) Frame = +2 Query: 110 EGVDIMVVRELTGGIYFGKPRGFGTNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGG 289 + VD+ ++RE T G Y G + + +I + A+ +RIA+ AF A Sbjct: 160 DNVDLCIIRENTEGEYSGLE-----HQSVSGVVESLKIITRAKSERIAKFAFSFALANNR 214 Query: 290 K-LCSVDKANVLE-ASMLWRKRVTAIASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTN 463 K + + KAN+++ A L+R +A +P +E + M VDNA+MQ V P+QFD +V Sbjct: 215 KKVTCIHKANIMKLADGLFRSTFHKVAESYPTLETNDMIVDNASMQAVARPQQFDVMVMP 274 Query: 464 NIFGDILSDEASMITGSIGMLPSASVG 544 N++G ILS+ + + G G++P ++G Sbjct: 275 NLYGGILSNVGAALVGGPGIVPGCNMG 301
>IDH3A_BOVIN (P41563) Isocitrate dehydrogenase [NAD] subunit alpha,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) (Isocitrate dehydrogenase subunits 3/4) Length = 366 Score = 77.8 bits (190), Expect = 2e-14 Identities = 52/180 (28%), Positives = 91/180 (50%), Gaps = 2/180 (1%) Frame = +2 Query: 11 LNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTND 190 L +R ++AN+RP + + V+I+ +RE T G Y G Sbjct: 112 LLLRKTFDLYANVRPCVSIEGY-------KTPYHDVNIVTIRENTEGEYSGIEHVIV--- 161 Query: 191 KGEETGFNTEIYSVAEIDRIARVAFEVARKRG-GKLCSVDKANVLEASM-LWRKRVTAIA 364 + + ++ + A RIA AFE AR + +V KAN++ S L+ ++ +A Sbjct: 162 --DGVVQSIKLITEAASKRIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVA 219 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASVG 544 D++ + MY+D + +V++P QFD +V N++GDILSD + + G +G+ PS ++G Sbjct: 220 ENCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIG 279
>IDH1_YEAST (P28834) Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial| precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 360 Score = 77.8 bits (190), Expect = 2e-14 Identities = 48/146 (32%), Positives = 86/146 (58%), Gaps = 3/146 (2%) Frame = +2 Query: 116 VDIMVVRELTGGIYFGKPRGFGTNDKGEETGFNTEIYSVAEIDRIARVAFEVARKRGGK- 292 +D++V+RE T G + G ++ + ++ + + +RIAR AF+ A+K K Sbjct: 134 IDLIVIRENTEGEFSGLE-----HESVPGVVESLKVMTRPKTERIARFAFDFAKKYNRKS 188 Query: 293 LCSVDKANVLE-ASMLWRKRVTAIAS-EFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNN 466 + +V KAN+++ L+R +T I E+PD+++S + VDNA+MQ V P QFD +VT + Sbjct: 189 VTAVHKANIMKLGDGLFRNIITEIGQKEYPDIDVSSIIVDNASMQAVAKPHQFDVLVTPS 248 Query: 467 IFGDILSDEASMITGSIGMLPSASVG 544 ++G IL + + + G G++ A+ G Sbjct: 249 MYGTILGNIGAALIGGPGLVAGANFG 274
>IDH_RICPR (Q9ZDR0) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)| (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) Length = 483 Score = 77.8 bits (190), Expect = 2e-14 Identities = 55/180 (30%), Positives = 95/180 (52%), Gaps = 2/180 (1%) Frame = +2 Query: 11 LNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTND 190 + IR L +FAN+RP +V R + +++ ++RE +Y G T++ Sbjct: 86 VTIRKTLQLFANIRP------VVSFYPFTRTLHPNLNLTIIRENEEDLYSGVEYR-QTHN 138 Query: 191 KGEETGFNTEIYSVAEIDRIARVAFEVARKRGGK-LCSVDKANVLEASM-LWRKRVTAIA 364 E + ++ S +I R AFE A K K + + K N+++ S ++ + IA Sbjct: 139 MYE----SMKLISHTGCKKIIRYAFEYAIKNNRKKVTCLTKDNIMKFSDGIFHRVFNEIA 194 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASVG 544 E+P + H +D +L P+ FD IVT+N++GDI+SD A+ I+GS+G+ SA++G Sbjct: 195 KEYPQINNEHYIIDIGTAKLATKPEIFDIIVTSNLYGDIISDVAAEISGSVGLAGSANIG 254
>DLPA_LEGPH (Q48806) Protein dlpA| Length = 615 Score = 77.0 bits (188), Expect = 3e-14 Identities = 53/195 (27%), Positives = 97/195 (49%), Gaps = 16/195 (8%) Frame = +2 Query: 8 LLNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFG-----KPR 172 ++ +R GL +FAN+RP + + ++ + ++RE + G+Y G P+ Sbjct: 101 VIQLRQGLDLFANVRPCFSID----------DQSKPFNFCIIRENSEGLYCGFDYFPLPK 150 Query: 173 GFGT---------NDKGEETGFNTEIYSVAEIDRIARVAFEVARKRG-GKLCSVDKANVL 322 + +E + S + + R+ AF+ A + G ++ DK NVL Sbjct: 151 AIHSLLAESQHWQTIPADEASCALRLQSKSGLTRLFDFAFKHAMQTGMPRVTLADKPNVL 210 Query: 323 -EASMLWRKRVTAIASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEAS 499 E+ RK + A +P ++ + VD A+ L+++P++F IV N+FGDILSD + Sbjct: 211 RESGEFTRKIFESTAQRYPKIQADILNVDAVALWLIKSPEKFGVIVAENMFGDILSDVGA 270 Query: 500 MITGSIGMLPSASVG 544 + G +G+ PSA++G Sbjct: 271 GVMGGLGLAPSANIG 285
>IDH3A_MACFA (Q28480) Isocitrate dehydrogenase [NAD] subunit alpha,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) (Fragment) Length = 347 Score = 77.0 bits (188), Expect = 3e-14 Identities = 55/182 (30%), Positives = 89/182 (48%), Gaps = 4/182 (2%) Frame = +2 Query: 11 LNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTND 190 L +R ++AN+RP + T V+I+ +RE T G Y G Sbjct: 93 LLLRKTFDLYANVRPCVSIEGYKTPYT-------DVNIVTIRENTEGEYSGIEHVI---- 141 Query: 191 KGEETGFNTEIYSVAE--IDRIARVAFEVARKRG-GKLCSVDKANVLEASM-LWRKRVTA 358 G I + E RIA AFE AR + +V KAN++ S L+ ++ Sbjct: 142 ---VDGVVQSIKLITEGGSKRIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCRE 198 Query: 359 IASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSAS 538 +A D++ + MY+D + +V++P QFD +V N++GDILSD + + G +G+ PS + Sbjct: 199 VAENCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGN 258 Query: 539 VG 544 +G Sbjct: 259 IG 260
>IDH3A_PONPY (Q5R678) Isocitrate dehydrogenase [NAD] subunit alpha,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 366 Score = 77.0 bits (188), Expect = 3e-14 Identities = 52/180 (28%), Positives = 90/180 (50%), Gaps = 2/180 (1%) Frame = +2 Query: 11 LNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTND 190 L +R ++AN+RP + T V+I+ +RE T G Y G Sbjct: 112 LLLRKTFDLYANVRPCVSIEGYKTPYT-------DVNIVTIRENTEGEYSGIEHVIV--- 161 Query: 191 KGEETGFNTEIYSVAEIDRIARVAFEVARKRG-GKLCSVDKANVLEASM-LWRKRVTAIA 364 + + ++ + RIA AFE AR + +V KAN++ S L+ ++ +A Sbjct: 162 --DGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVA 219 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASVG 544 D++ + MY+D + +V++P QFD +V N++GDILSD + + G +G+ PS ++G Sbjct: 220 ENCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIG 279
>IDH3A_MOUSE (Q9D6R2) Isocitrate dehydrogenase [NAD] subunit alpha,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 366 Score = 77.0 bits (188), Expect = 3e-14 Identities = 55/182 (30%), Positives = 89/182 (48%), Gaps = 4/182 (2%) Frame = +2 Query: 11 LNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTND 190 L +R ++AN+RP + T V+I+ +RE T G Y G Sbjct: 112 LLLRKTFDLYANVRPCVSIEGYKTPYT-------DVNIVTIRENTEGEYSGIEHVI---- 160 Query: 191 KGEETGFNTEIYSVAE--IDRIARVAFEVARKRG-GKLCSVDKANVLEASM-LWRKRVTA 358 G I + E RIA AFE AR + +V KAN++ S L+ ++ Sbjct: 161 ---VDGVVQSIKLITEEASKRIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCRE 217 Query: 359 IASEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSAS 538 +A D++ + MY+D + +V++P QFD +V N++GDILSD + + G +G+ PS + Sbjct: 218 VAENCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGN 277 Query: 539 VG 544 +G Sbjct: 278 IG 279
>IDH3A_HUMAN (P50213) Isocitrate dehydrogenase [NAD] subunit alpha,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) Length = 366 Score = 77.0 bits (188), Expect = 3e-14 Identities = 52/180 (28%), Positives = 90/180 (50%), Gaps = 2/180 (1%) Frame = +2 Query: 11 LNIRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTND 190 L +R ++AN+RP + T V+I+ +RE T G Y G Sbjct: 112 LLLRKTFDLYANVRPCVSIEGYKTPYT-------DVNIVTIRENTEGEYSGIEHVIV--- 161 Query: 191 KGEETGFNTEIYSVAEIDRIARVAFEVARKRG-GKLCSVDKANVLEASM-LWRKRVTAIA 364 + + ++ + RIA AFE AR + +V KAN++ S L+ ++ +A Sbjct: 162 --DGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVA 219 Query: 365 SEFPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASVG 544 D++ + MY+D + +V++P QFD +V N++GDILSD + + G +G+ PS ++G Sbjct: 220 ESCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIG 279
>IDH3G_MACFA (P41564) Isocitrate dehydrogenase [NAD] subunit gamma,| mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) (Fragment) Length = 355 Score = 76.6 bits (187), Expect = 4e-14 Identities = 52/178 (29%), Positives = 96/178 (53%), Gaps = 2/178 (1%) Frame = +2 Query: 17 IRAGLGVFANLRPATVLPQLVDASTLKREVAEGVDIMVVRELTGGIYFGKPRGFGTNDKG 196 +R L ++AN+ LP +V + +DI++VRE T G Y ++ Sbjct: 97 LRTSLDLYANVIHCKSLPGVVTRH-------KDIDILIVRENTEGEYSSLE-----HESV 144 Query: 197 EETGFNTEIYSVAEIDRIARVAFEVARKRGGK-LCSVDKANVLE-ASMLWRKRVTAIASE 370 + +I + A+ RIA AF++A++ G K + +V KAN+++ L+ + +A+ Sbjct: 145 AGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAAR 204 Query: 371 FPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASVG 544 +P + +M VDN MQLV P+QFD +V N++G+I+++ + + G G++ A+ G Sbjct: 205 YPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYG 262 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 76,878,495 Number of Sequences: 219361 Number of extensions: 1490500 Number of successful extensions: 5391 Number of sequences better than 10.0: 283 Number of HSP's better than 10.0 without gapping: 4802 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4981 length of database: 80,573,946 effective HSP length: 105 effective length of database: 57,541,041 effective search space used: 4315578075 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
