Clone Information

BLAST Search Result

Clone Name	bags7l05
Clone Library Name	barley_pub

No.	Definition	Score (bits)	E Value
1	HERC3_HUMAN (Q15034) HECT domain and RCC1-like domain protein 3	77	2e-14
2	HERC2_DROME (Q9VR91) HECT domain and RCC1-like domain-containing...	70	2e-12
3	RCBT1_MOUSE (Q6NXM2) RCC1 and BTB domain-containing protein 1 (R...	68	1e-11
4	RCBT1_HUMAN (Q8NDN9) RCC1 and BTB domain-containing protein 1 (R...	68	1e-11
5	HERC2_HUMAN (O95714) HECT domain and RCC1-like domain-containing...	67	3e-11
6	HERC2_MOUSE (Q4U2R1) HECT domain and RCC1-like domain-containing...	66	4e-11
7	RCBT2_RAT (Q6P798) RCC1 and BTB domain-containing protein 2 (Reg...	62	6e-10
8	RCBT2_PONPY (Q5RCZ7) RCC1 and BTB domain-containing protein 2 (R...	62	6e-10
9	RCBT2_MOUSE (Q99LJ7) RCC1 and BTB domain-containing protein 2 (R...	62	6e-10
10	RCBT2_HUMAN (O95199) RCC1 and BTB domain-containing protein 2 (R...	62	6e-10
11	NEK9_MOUSE (Q8K1R7) Serine/threonine-protein kinase Nek9 (EC 2.7...	62	7e-10
12	RCC2_BRARE (Q6NYE2) Protein RCC2 homolog	62	7e-10
13	NEK9_HUMAN (Q8TD19) Serine/threonine-protein kinase Nek9 (EC 2.7...	62	9e-10
14	MYCB2_MOUSE (Q7TPH6) Probable ubiquitin ligase protein MYCBP2 (E...	60	4e-09
15	MYCB2_HUMAN (O75592) Probable ubiquitin ligase protein MYCBP2 (E...	60	4e-09
16	RCC2_HUMAN (Q9P258) Protein RCC2 (Telophase disk protein of 60 k...	60	4e-09
17	HERC5_HUMAN (Q9UII4) HECT domain and RCC1-like domain-containing...	59	5e-09
18	RCC2_MOUSE (Q8BK67) Protein RCC2	59	8e-09
19	ALS2_MOUSE (Q920R0) Alsin (Amyotrophic lateral sclerosis protein...	56	4e-08
20	RCC2_XENLA (Q52KW8) Protein RCC2 homolog	56	4e-08
21	NEK9_XENLA (Q7ZZC8) Serine/threonine-protein kinase Nek9 (EC 2.7...	56	4e-08
22	RPGR_HUMAN (Q92834) X-linked retinitis pigmentosa GTPase regulator	55	7e-08
23	RPGR_MOUSE (Q9R0X5) X-linked retinitis pigmentosa GTPase regulat...	55	7e-08
24	ALS2_PANTR (Q5BIW4) Alsin (Amyotrophic lateral sclerosis protein...	55	1e-07
25	ALS2_HUMAN (Q96Q42) Alsin (Amyotrophic lateral sclerosis protein 2)	55	1e-07
26	GNEFR_MOUSE (Q80YD6) Guanine nucleotide exchange factor-related ...	54	3e-07
27	RPGRH_CAEEL (Q5DX34) X-linked retinitis pigmentosa GTPase regula...	52	8e-07
28	RPGR_CANFA (Q9N1T2) X-linked retinitis pigmentosa GTPase regulator	51	1e-06
29	GNEFR_HUMAN (Q9UGK8) Guanine nucleotide exchange factor-related ...	50	2e-06
30	NEK8_HUMAN (Q86SG6) Serine/threonine-protein kinase Nek8 (EC 2.7...	50	3e-06
31	NEK8_MOUSE (Q91ZR4) Serine/threonine-protein kinase Nek8 (EC 2.7...	50	4e-06
32	RCC1_SCHPO (P28745) Protein pim1 (Poly(A)+ RNA transport protein 2)	49	5e-06
33	RPM1_CAEEL (Q17551) Ubiquitin ligase protein rpm-1 (EC 6.3.2.-) ...	49	5e-06
34	RCC1_YEAST (P21827) Regulator of chromosome condensation (PRP20 ...	49	5e-06
35	NEK8_BRARE (Q90XC2) Serine/threonine-protein kinase Nek8 (EC 2.7...	49	6e-06
36	WBS16_MOUSE (Q9CYF5) Williams-Beuren syndrome chromosome region ...	49	8e-06
37	RCC1_MOUSE (Q8VE37) Regulator of chromosome condensation (Chromo...	48	1e-05
38	RCC1_MESAU (P23800) Regulator of chromosome condensation (Chromo...	48	1e-05
39	RCC1_DROME (P25171) Regulator of chromosome condensation (Chroma...	47	2e-05
40	RCC1_XENLA (P25183) Regulator of chromosome condensation	47	2e-05
41	HIW_DROME (Q9NB71) Ubiquitin ligase protein highwire (EC 6.3.2.-...	47	2e-05
42	WBS16_HUMAN (Q96I51) Williams-Beuren syndrome chromosome region ...	47	3e-05
43	RCC1_HUMAN (P18754) Regulator of chromosome condensation (Chromo...	46	4e-05
44	RCC1_CANAL (P52499) Protein RCC1	45	9e-05
45	FBX24_MOUSE (Q9D417) F-box only protein 24	42	8e-04
46	FBX24_HUMAN (O75426) F-box only protein 24	39	0.007
47	RCC1_CAEEL (Q18211) Regulator of chromosome condensation (Cell c...	38	0.015
48	ATS1_YEAST (P31386) Protein ATS1 (Alpha-tubulin suppressor 1)	33	0.28
49	YB9W_YEAST (P38352) F-box protein YBR280C	33	0.36
50	WRK42_ARATH (Q9XEC3) Probable WRKY transcription factor 42 (WRKY...	30	3.1
51	WRK47_ARATH (Q9ZSI7) Probable WRKY transcription factor 47 (WRKY...	30	3.1
52	UPL1_ARATH (Q8GY23) E3 ubiquitin protein ligase UPL1 (EC 6.3.2.-...	30	3.1
53	UPL2_ARATH (Q8H0T4) E3 ubiquitin protein ligase UPL2 (EC 6.3.2.-...	30	4.0
54	LCTL_MOUSE (Q8K1F9) Lactase-like protein precursor (Klotho/lacta...	29	6.8
55	YBBS_ECOLI (P0ACR0) Putative HTH-type transcriptional regulator ...	29	6.8
56	YBBS_ECO57 (P0ACR1) Putative HTH-type transcriptional regulator ...	29	6.8
57	YR335_MIMIV (Q5UQT2) Hypothetical protein R335	29	6.8
58	KPC2_CAEEL (P90980) Protein kinase C-like 2 (EC 2.7.11.13) (PKC2)	28	8.9
59	WRK25_ARATH (O22921) Probable WRKY transcription factor 25 (WRKY...	28	8.9

>HERC3_HUMAN (Q15034) HECT domain and RCC1-like domain protein 3|
          Length = 1050

 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 37/93 (39%), Positives = 54/93 (58%)
 Frame = +1

Query: 19  GKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWGR 198
           G ++GWG N  GQ+G+ D  D  SP  V     QK+V ++CG  HT  LT++  +F++G 
Sbjct: 209 GAVFGWGMNNAGQLGLSDEKDRESPCHVKLLRTQKVVYISCGEEHTAVLTKSGGVFTFGA 268

Query: 199 GASGQLGHGEIIDRNTPKMIDALSLDGSACKQL 297
           G+ GQLGH  + D   P+ +  L L GS   Q+
Sbjct: 269 GSCGQLGHDSMNDEVNPRRV--LELMGSEVTQI 299



 Score = 60.1 bits (144), Expect = 3e-09
 Identities = 30/69 (43%), Positives = 43/69 (62%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSW 192
           EDG++Y  G N  GQ+G E   +   P ++    +Q I+ VACG  H+LAL++   +FSW
Sbjct: 51  EDGEVYTCGLNTKGQLGHEREGN--KPEQIGALADQHIIHVACGESHSLALSDRGQLFSW 108

Query: 193 GRGASGQLG 219
           G G+ GQLG
Sbjct: 109 GAGSDGQLG 117



 Score = 55.5 bits (132), Expect = 7e-08
 Identities = 31/90 (34%), Positives = 51/90 (56%), Gaps = 2/90 (2%)
 Frame = +1

Query: 4   ARGEDGKLYGWGWNKFGQVGVEDNVDHCS-PVEVNFPDEQKIVQVACGWRHTLALTENKN 180
           A  + G+L+ WG    GQ+G+    D  + P  +   ++Q I+QV+CG  H LAL  +  
Sbjct: 98  ALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQ 157

Query: 181 IFSWGRGASGQLGHG-EIIDRNTPKMIDAL 267
            F+WG+ + GQLG G E   + +P+ + +L
Sbjct: 158 FFTWGKNSHGQLGLGKEFPSQASPQRVRSL 187



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 29/83 (34%), Positives = 44/83 (53%), Gaps = 1/83 (1%)
 Frame = +1

Query: 4   ARGEDGKLYGWGWNKFGQVGV-EDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKN 180
           A   DG+ + WG N  GQ+G+ ++     SP  V   +   + QVA G  H+ AL+ +  
Sbjct: 151 ALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLSGA 210

Query: 181 IFSWGRGASGQLGHGEIIDRNTP 249
           +F WG   +GQLG  +  DR +P
Sbjct: 211 VFGWGMNNAGQLGLSDEKDRESP 233



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 26/81 (32%), Positives = 42/81 (51%), Gaps = 2/81 (2%)
 Frame = +1

Query: 34  WGWNKFGQVGVEDNVDH--CSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWGRGAS 207
           WG+   GQ G+  N+      P    F  ++ + +VACG  H++ L E+  +++ G    
Sbjct: 4   WGYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGLNTK 63

Query: 208 GQLGHGEIIDRNTPKMIDALS 270
           GQLGH    + N P+ I AL+
Sbjct: 64  GQLGHER--EGNKPEQIGALA 82



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 26/83 (31%), Positives = 43/83 (51%), Gaps = 1/83 (1%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKN-IFS 189
           + G ++ +G    GQ+G +   D  +P  V      ++ Q+ACG +HTLA   +   I++
Sbjct: 259 KSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIACGRQHTLAFVPSSGLIYA 318

Query: 190 WGRGASGQLGHGEIIDRNTPKMI 258
           +G GA GQLG G   +   P  +
Sbjct: 319 FGCGARGQLGTGHTCNVKCPSPV 341

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>HERC2_DROME (Q9VR91) HECT domain and RCC1-like domain-containing protein 2|
          Length = 4912

 Score = 70.5 bits (171), Expect = 2e-12
 Identities = 39/92 (42%), Positives = 53/92 (57%), Gaps = 2/92 (2%)
 Frame = +1

Query: 1    SARGEDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWR--HTLALTEN 174
            +A    G+LY WG  ++G++G  DN     P  V     +++VQVACG R   TLALTE+
Sbjct: 3138 AAISSQGELYTWGLGEYGRLGHGDNTTQLKPKLVTALAGRRVVQVACGSRDAQTLALTED 3197

Query: 175  KNIFSWGRGASGQLGHGEIIDRNTPKMIDALS 270
              +FSWG G  G+LG G     +TP  I+ LS
Sbjct: 3198 GAVFSWGDGDFGKLGRGGSEGSDTPHEIERLS 3229



 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 27/84 (32%), Positives = 52/84 (61%)
 Frame = +1

Query: 16   DGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWG 195
            +G++Y WG  + G++G  + + +  P  V   +   +  +ACG  H+ A+T + ++ +WG
Sbjct: 4154 EGEVYAWGEGEDGKLGHGNRMSYDRPKLVEHLNGMSVADIACGSAHSAAITASGHVLTWG 4213

Query: 196  RGASGQLGHGEIIDRNTPKMIDAL 267
            +G  G+LGHG+  D+  PK+++AL
Sbjct: 4214 KGRYGRLGHGDSEDQLRPKLVEAL 4237



 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 29/85 (34%), Positives = 48/85 (56%)
 Frame = +1

Query: 16   DGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWG 195
            DGK++ WG  + G++G  +      P  V     +KI  VACG  H+ A++    +++WG
Sbjct: 3091 DGKVFSWGEGEDGKLGHGNRTTLDKPRLVEALRAKKIRDVACGSSHSAAISSQGELYTWG 3150

Query: 196  RGASGQLGHGEIIDRNTPKMIDALS 270
             G  G+LGHG+   +  PK++ AL+
Sbjct: 3151 LGEYGRLGHGDNTTQLKPKLVTALA 3175



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 33/89 (37%), Positives = 49/89 (55%), Gaps = 4/89 (4%)
 Frame = +1

Query: 13   EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQ----KIVQVACGWRHTLALTENKN 180
            +DGK+Y  G    G++G+   V H  P+    P  +    K V V  G +H LALT +  
Sbjct: 3036 QDGKVYACGEGTNGRLGL--GVTHNVPLPHQLPVLRQYVVKKVAVHSGGKHALALTLDGK 3093

Query: 181  IFSWGRGASGQLGHGEIIDRNTPKMIDAL 267
            +FSWG G  G+LGHG     + P++++AL
Sbjct: 3094 VFSWGEGEDGKLGHGNRTTLDKPRLVEAL 3122



 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 31/104 (29%), Positives = 53/104 (50%), Gaps = 5/104 (4%)
 Frame = +1

Query: 16   DGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVAC--GWRHTLALTENKNIFS 189
            DGKL+  G+   G++GV  +     P  +       + +VA   G +H LALT    +++
Sbjct: 4100 DGKLFATGYGSGGRLGVGGSDSWAIPTLLGSLQHVFVKKVAVNSGGKHCLALTTEGEVYA 4159

Query: 190  WGRGASGQLGHGEIIDRNTPKMID---ALSLDGSACKQLESSNV 312
            WG G  G+LGHG  +  + PK+++    +S+   AC    S+ +
Sbjct: 4160 WGEGEDGKLGHGNRMSYDRPKLVEHLNGMSVADIACGSAHSAAI 4203



 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 26/81 (32%), Positives = 43/81 (53%)
 Frame = +1

Query: 28  YGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWGRGAS 207
           Y WG  +  ++G  D      P ++   ++  +  V CG  ++ A+T   N+ +WGRG  
Sbjct: 638 YSWGTGEDHRLGHGDTHARAVPTKIAALEQHCVQSVYCGCSYSAAITCGGNLLTWGRGTY 697

Query: 208 GQLGHGEIIDRNTPKMIDALS 270
            +LGHG   DR+ P ++ ALS
Sbjct: 698 ARLGHGNSDDRSLPTLVVALS 718



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 25/71 (35%), Positives = 41/71 (57%)
 Frame = +1

Query: 13   EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSW 192
            EDG ++ WG   FG++G   +    +P E+       +VQ+ CG + +LALT    +++W
Sbjct: 3196 EDGAVFSWGDGDFGKLGRGGSEGSDTPHEIERLSGIGVVQIECGAQFSLALTRAGEVWTW 3255

Query: 193  GRGASGQLGHG 225
            G+G   +LGHG
Sbjct: 3256 GKGDYYRLGHG 3266



 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 27/86 (31%), Positives = 47/86 (54%), Gaps = 1/86 (1%)
 Frame = +1

Query: 13   EDGKLYGWGWNKFGQVGVEDNVDHCS-PVEVNFPDEQKIVQVACGWRHTLALTENKNIFS 189
            + G +Y WG   F ++G   +VDH   P +V     +KI+ +A G  H +A +++  +++
Sbjct: 4311 KSGAVYTWGKGDFHRLG-HGSVDHVRRPKKVAALQGKKIISIATGSLHCVACSDSGEVYT 4369

Query: 190  WGRGASGQLGHGEIIDRNTPKMIDAL 267
            WG    GQLG G +     P+++ AL
Sbjct: 4370 WGDNDEGQLGDGTVTAIQRPRLVAAL 4395



 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 26/86 (30%), Positives = 48/86 (55%), Gaps = 1/86 (1%)
 Frame = +1

Query: 13   EDGKLYGWGWNKFGQVGVEDNVDHCS-PVEVNFPDEQKIVQVACGWRHTLALTENKNIFS 189
            +D  ++ WG   +G++G     D C  P ++       +V+V CG + ++ALT++  +++
Sbjct: 4259 DDDNVWSWGDGDYGKLG-RGGSDGCKLPYKIESLAGLGVVKVECGSQFSVALTKSGAVYT 4317

Query: 190  WGRGASGQLGHGEIIDRNTPKMIDAL 267
            WG+G   +LGHG +     PK + AL
Sbjct: 4318 WGKGDFHRLGHGSVDHVRRPKKVAAL 4343



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 27/86 (31%), Positives = 45/86 (52%), Gaps = 2/86 (2%)
 Frame = +1

Query: 19   GKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGW--RHTLALTENKNIFSW 192
            G +  WG  ++G++G  D+ D   P  V      + + +ACG     TL +T++ N++SW
Sbjct: 4207 GHVLTWGKGRYGRLGHGDSEDQLRPKLVEALLGYRAIDIACGSGDAQTLCITDDDNVWSW 4266

Query: 193  GRGASGQLGHGEIIDRNTPKMIDALS 270
            G G  G+LG G       P  I++L+
Sbjct: 4267 GDGDYGKLGRGGSDGCKLPYKIESLA 4292



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 27/85 (31%), Positives = 43/85 (50%), Gaps = 2/85 (2%)
 Frame = +1

Query: 19  GKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGW--RHTLALTENKNIFSW 192
           G L  WG   + ++G  ++ D   P  V    +  +V VA G    H+LALT    +F+W
Sbjct: 687 GNLLTWGRGTYARLGHGNSDDRSLPTLVVALSDHMVVDVALGSGDAHSLALTSEGLVFAW 746

Query: 193 GRGASGQLGHGEIIDRNTPKMIDAL 267
           G G  G+LG+G       P ++++L
Sbjct: 747 GDGDYGKLGNGNCNGSLQPILVESL 771



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 28/87 (32%), Positives = 38/87 (43%), Gaps = 2/87 (2%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVA--CGWRHTLALTENKNIF 186
           ++GKLY W   K              P+ +        + +A  C  RH LA+  N N +
Sbjct: 589 QEGKLYTWRLAK----------PEAEPLPMEEVAHDVFISIAGHCEGRHFLAIDSNHNAY 638

Query: 187 SWGRGASGQLGHGEIIDRNTPKMIDAL 267
           SWG G   +LGHG+   R  P  I AL
Sbjct: 639 SWGTGEDHRLGHGDTHARAVPTKIAAL 665



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 34/107 (31%), Positives = 48/107 (44%), Gaps = 7/107 (6%)
 Frame = +1

Query: 4    ARGEDGKLYGWGWNK-FGQVGVEDNVDHCS-PVEVNFPDEQKIVQVACGWRHTLALTENK 177
            A   +G+LY WG     G   VE +V  CS P  V+    ++IV VA    H LAL+ + 
Sbjct: 786  ALSSEGQLYTWGKATCLGHQLVERSVQGCSVPRLVSSLQHKRIVDVAVSVAHCLALSSSG 845

Query: 178  NIFSWGRGASGQLGHGEIIDR---NTPKMID--ALSLDGSACKQLES 303
             +F WGR  S Q+    +       TP ++        G AC   +S
Sbjct: 846  EVFGWGRNDSQQICPASVSSEPLLRTPILVSLPTFPASGIACTSAQS 892



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 25/86 (29%), Positives = 41/86 (47%)
 Frame = +1

Query: 10   GEDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFS 189
            G    +YGWG N  GQ+G  +     +P         + VQ+A G +   A+T +  +F+
Sbjct: 4046 GGASTIYGWGHNHRGQLGGLEGSRIKTPTPCEALSLLRPVQLAGGEQSLFAVTPDGKLFA 4105

Query: 190  WGRGASGQLGHGEIIDRNTPKMIDAL 267
             G G+ G+LG G       P ++ +L
Sbjct: 4106 TGYGSGGRLGVGGSDSWAIPTLLGSL 4131



 Score = 34.7 bits (78), Expect = 0.12
 Identities = 21/58 (36%), Positives = 30/58 (51%)
 Frame = +1

Query: 4    ARGEDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENK 177
            A  + G++Y WG N  GQ+G         P  V     + IV+V CG  HTLAL+ ++
Sbjct: 4360 ACSDSGEVYTWGDNDEGQLGDGTVTAIQRPRLVAALQGKHIVKVTCGSAHTLALSTSQ 4417



 Score = 32.3 bits (72), Expect = 0.62
 Identities = 17/48 (35%), Positives = 25/48 (52%)
 Frame = +1

Query: 19   GKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLA 162
            G++Y WG N  GQ G  +   +  P  V   D   + +VACG  H++A
Sbjct: 3302 GQVYAWGDNDHGQQGSGNTFVNKKPALVIGLDAVFVNRVACGSSHSIA 3349

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>RCBT1_MOUSE (Q6NXM2) RCC1 and BTB domain-containing protein 1 (Regulator of|
           chromosome condensation and BTB domain-containing
           protein 1)
          Length = 531

 Score = 67.8 bits (164), Expect = 1e-11
 Identities = 31/82 (37%), Positives = 49/82 (59%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSW 192
           + G++YGWG+N  GQ+G+ +N +  +PV V       + Q+ CG+ HTLALT+   +++W
Sbjct: 198 DSGEVYGWGYNGNGQLGLGNNGNQLTPVRVAALHGMCVNQIVCGYAHTLALTDEGLLYAW 257

Query: 193 GRGASGQLGHGEIIDRNTPKMI 258
           G    GQLG G   +  +P  I
Sbjct: 258 GANTYGQLGTGSKNNLLSPTQI 279



 Score = 61.6 bits (148), Expect = 9e-10
 Identities = 30/89 (33%), Positives = 51/89 (57%), Gaps = 1/89 (1%)
 Frame = +1

Query: 4   ARGEDGKLYGWGWNKFGQVGVEDNVDHCSPVEV-NFPDEQKIVQVACGWRHTLALTENKN 180
           A   DG+L+ WG+N  GQVG     +  +P +V N    +++V +ACG   ++A+ ++  
Sbjct: 142 ALAADGELFAWGYNNCGQVGSGSTANQPTPRKVTNCLHTKRVVNIACGQTSSMAVLDSGE 201

Query: 181 IFSWGRGASGQLGHGEIIDRNTPKMIDAL 267
           ++ WG   +GQLG G   ++ TP  + AL
Sbjct: 202 VYGWGYNGNGQLGLGNNGNQLTPVRVAAL 230



 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 30/84 (35%), Positives = 49/84 (58%), Gaps = 2/84 (2%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHCSPVEV--NFPDEQKIVQVACGWRHTLALTENKNIF 186
           EDG +Y WG N + Q+G        +PV+V  N   +Q +++VACG  H++AL  +  +F
Sbjct: 92  EDGVVYAWGHNGYSQLGNGTTNQGIAPVQVCTNLLIKQ-VIEVACGSHHSMALAADGELF 150

Query: 187 SWGRGASGQLGHGEIIDRNTPKMI 258
           +WG    GQ+G G   ++ TP+ +
Sbjct: 151 AWGYNNCGQVGSGSTANQPTPRKV 174



 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 26/73 (35%), Positives = 38/73 (52%), Gaps = 3/73 (4%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHT-LALTENKNIFS 189
           ++G LY WG N +GQ+G     +  SP ++    E+ I   AC   HT  A T+  +++ 
Sbjct: 250 DEGLLYAWGANTYGQLGTGSKNNLLSPTQIMVEKERVIEIAACHSTHTSAAKTQGGHVYM 309

Query: 190 WG--RGASGQLGH 222
           WG  RG S  L H
Sbjct: 310 WGQCRGQSVILPH 322



 Score = 32.7 bits (73), Expect = 0.47
 Identities = 19/72 (26%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACG-WRHTLALTENKNIFS 189
           ++ +++ +G N    +G  DN     P ++     +KI  ++ G   H L  TE+  +++
Sbjct: 39  DNDEVFVFGLNYSNCLGTGDNQSTLVPKKLEALCGKKIKSLSYGSGPHVLLTTEDGVVYA 98

Query: 190 WGRGASGQLGHG 225
           WG     QLG+G
Sbjct: 99  WGHNGYSQLGNG 110

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>RCBT1_HUMAN (Q8NDN9) RCC1 and BTB domain-containing protein 1 (Regulator of|
           chromosome condensation and BTB domain-containing
           protein 1) (Chronic lymphocytic leukemia deletion region
           gene 7 protein) (CLL deletion region gene 7 protein)
          Length = 531

 Score = 67.8 bits (164), Expect = 1e-11
 Identities = 29/71 (40%), Positives = 46/71 (64%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSW 192
           ++G++YGWG+N  GQ+G+ +N +  +PV V       + Q+ CG+ HTLALT+   +++W
Sbjct: 198 DNGEVYGWGYNGNGQLGLGNNGNQLTPVRVAALHSVCVNQIVCGYAHTLALTDEGLLYAW 257

Query: 193 GRGASGQLGHG 225
           G    GQLG G
Sbjct: 258 GANTYGQLGTG 268



 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 39/107 (36%), Positives = 59/107 (55%), Gaps = 6/107 (5%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHCSPVEV--NFPDEQKIVQVACGWRHTLALTENKNIF 186
           EDG +Y WG N + Q+G        +PV+V  N   +Q +V+VACG  H++AL  +  +F
Sbjct: 92  EDGVVYAWGHNGYSQLGNGTTNQGIAPVQVCTNLLIKQ-VVEVACGSHHSMALAADGEVF 150

Query: 187 SWGRGASGQLGHGEIIDRNTP-KMIDALSLD---GSACKQLESSNVV 315
           +WG    GQ+G G   ++ TP K+ + L +    G AC Q  S  V+
Sbjct: 151 AWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVL 197



 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 30/89 (33%), Positives = 51/89 (57%), Gaps = 1/89 (1%)
 Frame = +1

Query: 4   ARGEDGKLYGWGWNKFGQVGVEDNVDHCSPVEV-NFPDEQKIVQVACGWRHTLALTENKN 180
           A   DG+++ WG+N  GQVG     +  +P +V N    +++V +ACG   ++A+ +N  
Sbjct: 142 ALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGE 201

Query: 181 IFSWGRGASGQLGHGEIIDRNTPKMIDAL 267
           ++ WG   +GQLG G   ++ TP  + AL
Sbjct: 202 VYGWGYNGNGQLGLGNNGNQLTPVRVAAL 230



 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 25/73 (34%), Positives = 38/73 (52%), Gaps = 3/73 (4%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHT-LALTENKNIFS 189
           ++G LY WG N +GQ+G  +  +  SP  +    E+ +   AC   HT  A T+  +++ 
Sbjct: 250 DEGLLYAWGANTYGQLGTGNKNNLLSPAHIMVEKERVVEIAACHSAHTSAAKTQGGHVYM 309

Query: 190 WG--RGASGQLGH 222
           WG  RG S  L H
Sbjct: 310 WGQCRGQSVILPH 322



 Score = 32.0 bits (71), Expect = 0.80
 Identities = 19/72 (26%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACG-WRHTLALTENKNIFS 189
           ++ +++ +G N    +G  DN     P ++     +KI  ++ G   H L  TE+  +++
Sbjct: 39  DNDEVFVFGLNYSNCLGTGDNQSTLVPKKLEGLCGKKIKSLSYGSGPHVLLSTEDGVVYA 98

Query: 190 WGRGASGQLGHG 225
           WG     QLG+G
Sbjct: 99  WGHNGYSQLGNG 110

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>HERC2_HUMAN (O95714) HECT domain and RCC1-like domain-containing protein 2|
          Length = 4834

 Score = 66.6 bits (161), Expect = 3e-11
 Identities = 37/95 (38%), Positives = 52/95 (54%), Gaps = 2/95 (2%)
 Frame = +1

Query: 1    SARGEDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWR--HTLALTEN 174
            +A    G+LY WG  ++G++G  DN     P  V      +++QVACG R   TLALT+ 
Sbjct: 3112 AALTSSGELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDE 3171

Query: 175  KNIFSWGRGASGQLGHGEIIDRNTPKMIDALSLDG 279
              +FSWG G  G+LG G     N P+ I+ L+  G
Sbjct: 3172 GLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQG 3206



 Score = 66.2 bits (160), Expect = 4e-11
 Identities = 47/145 (32%), Positives = 66/145 (45%), Gaps = 3/145 (2%)
 Frame = +1

Query: 16  DGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGW--RHTLALTENKNIFS 189
           +G+LY WG   +G++G   + D   P+ V      K++ VACG     TLA+TEN  ++S
Sbjct: 569 EGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTENGQVWS 628

Query: 190 WGRGASGQLGHGEIIDRNTPKMIDAL-SLDGSACKQLESSNVVPMTVKVWVSPSERFALV 366
           WG G  G+LG G      TPK+I+ L  LD                VKV        AL 
Sbjct: 629 WGDGDYGKLGRGGSDGCKTPKLIEKLQDLD---------------VVKVRCGSQFSIALT 673

Query: 367 PDENVCKSGNGTDKHAPEGDAKRMR 441
            D  V   G G ++    G  + +R
Sbjct: 674 KDGQVYSWGKGDNQRLGHGTEEHVR 698



 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 28/84 (33%), Positives = 47/84 (55%)
 Frame = +1

Query: 16   DGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWG 195
            DGK++ WG    G++G    ++   P  +     ++I  +ACG  H+ ALT +  +++WG
Sbjct: 3065 DGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTWG 3124

Query: 196  RGASGQLGHGEIIDRNTPKMIDAL 267
             G  G+LGHG+   +  PKM+  L
Sbjct: 3125 LGEYGRLGHGDNTTQLKPKMVKVL 3148



 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 31/86 (36%), Positives = 46/86 (53%), Gaps = 2/86 (2%)
 Frame = +1

Query: 19   GKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGW--RHTLALTENKNIFSW 192
            G LY WG  ++G++G  D+ D   P  V      ++V +ACG     TL LT++  ++SW
Sbjct: 4110 GDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVVDIACGSGDAQTLCLTDDDTVWSW 4169

Query: 193  GRGASGQLGHGEIIDRNTPKMIDALS 270
            G G  G+LG G       P  ID+L+
Sbjct: 4170 GDGDYGKLGRGGSDGCKVPMKIDSLT 4195



 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 27/86 (31%), Positives = 52/86 (60%), Gaps = 1/86 (1%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHC-SPVEVNFPDEQKIVQVACGWRHTLALTENKNIFS 189
           E+G+++ WG   +G++G     D C +P  +    +  +V+V CG + ++ALT++  ++S
Sbjct: 622 ENGQVWSWGDGDYGKLG-RGGSDGCKTPKLIEKLQDLDVVKVRCGSQFSIALTKDGQVYS 680

Query: 190 WGRGASGQLGHGEIIDRNTPKMIDAL 267
           WG+G + +LGHG       PK+++ L
Sbjct: 681 WGKGDNQRLGHGTEEHVRYPKLLEGL 706



 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 29/87 (33%), Positives = 47/87 (54%), Gaps = 4/87 (4%)
 Frame = +1

Query: 19  GKLYGWGWNKFGQVGVEDNVDHCSPVEVN-FPDEQK---IVQVACGWRHTLALTENKNIF 186
           G++Y WG    G++G  D V    P  ++ F  +Q    +V +ACG  ++ A+T    ++
Sbjct: 514 GEVYSWGCGDGGRLGHGDTVPLEEPKVISAFSGKQAGKHVVHIACGSTYSAAITAEGELY 573

Query: 187 SWGRGASGQLGHGEIIDRNTPKMIDAL 267
           +WGRG  G+LGHG   D   P ++  L
Sbjct: 574 TWGRGNYGRLGHGSSEDEAIPMLVAGL 600



 Score = 55.1 bits (131), Expect = 9e-08
 Identities = 26/88 (29%), Positives = 49/88 (55%)
 Frame = +1

Query: 4    ARGEDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNI 183
            A   +G++Y WG  + G++G  +      P  +      ++V VA G  H+  +T   ++
Sbjct: 4053 ALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDL 4112

Query: 184  FSWGRGASGQLGHGEIIDRNTPKMIDAL 267
            ++WG+G  G+LGH +  D+  PK+++AL
Sbjct: 4113 YTWGKGRYGRLGHSDSEDQLKPKLVEAL 4140



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 24/85 (28%), Positives = 49/85 (57%)
 Frame = +1

Query: 13   EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSW 192
            ++G ++ WG   FG++G   +     P  +   + Q + Q+ CG + +LALT++  +++W
Sbjct: 3170 DEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTW 3229

Query: 193  GRGASGQLGHGEIIDRNTPKMIDAL 267
            G+G   +LGHG  +    P++++ L
Sbjct: 3230 GKGDYFRLGHGSDVHVRKPQVVEGL 3254



 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 28/86 (32%), Positives = 45/86 (52%), Gaps = 2/86 (2%)
 Frame = +1

Query: 16   DGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVAC--GWRHTLALTENKNIFS 189
            DGKLY  G+   G++G+       +P  +       I +VA   G +H LAL+    ++S
Sbjct: 4003 DGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYS 4062

Query: 190  WGRGASGQLGHGEIIDRNTPKMIDAL 267
            WG    G+LGHG     + P++I++L
Sbjct: 4063 WGEAEDGKLGHGNRSPCDRPRVIESL 4088



 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 24/86 (27%), Positives = 48/86 (55%), Gaps = 1/86 (1%)
 Frame = +1

Query: 13   EDGKLYGWGWNKFGQVGVEDNVDHCS-PVEVNFPDEQKIVQVACGWRHTLALTENKNIFS 189
            +D  ++ WG   +G++G     D C  P++++      +V+V CG + ++ALT++  +++
Sbjct: 4162 DDDTVWSWGDGDYGKLG-RGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYT 4220

Query: 190  WGRGASGQLGHGEIIDRNTPKMIDAL 267
            WG+G   +LGHG       P+ +  L
Sbjct: 4221 WGKGDYHRLGHGSDDHVRRPRQVQGL 4246



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 31/112 (27%), Positives = 50/112 (44%)
 Frame = +1

Query: 13   EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSW 192
            + G ++ WG   + ++G   +V    P  V     +KIV VA G  H LA+T++  +++W
Sbjct: 3222 KSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAW 3281

Query: 193  GRGASGQLGHGEIIDRNTPKMIDALSLDGSACKQLESSNVVPMTVKVWVSPS 348
            G    GQ G+G       P ++  L           SS+ V  T     +PS
Sbjct: 3282 GDNDHGQQGNGTTTVNRKPTLVQGLEGQKITRVACGSSHSVAWTTVDVATPS 3333



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 23/85 (27%), Positives = 42/85 (49%)
 Frame = +1

Query: 13   EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSW 192
            + G +Y WG   + ++G   +     P +V     +K++ +A G  H +  TE+  +++W
Sbjct: 4214 KSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTW 4273

Query: 193  GRGASGQLGHGEIIDRNTPKMIDAL 267
            G    GQLG G       P+++ AL
Sbjct: 4274 GDNDEGQLGDGTTNAIQRPRLVAAL 4298



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 22/49 (44%), Positives = 31/49 (63%)
 Frame = +1

Query: 121  KIVQVACGWRHTLALTENKNIFSWGRGASGQLGHGEIIDRNTPKMIDAL 267
            K V V  G RH  ALT +  +FSWG G  G+LGH   ++ + P++I+AL
Sbjct: 3048 KKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEAL 3096



 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 25/68 (36%), Positives = 35/68 (51%), Gaps = 2/68 (2%)
 Frame = +1

Query: 73  NVDHCSPVEVNFPDEQKIVQVAC--GWRHTLALTENKNIFSWGRGASGQLGHGEIIDRNT 246
           N D  +P  V     + IV++A      H LAL     ++SWG G  G+LGHG+ +    
Sbjct: 478 NSDTLAPQLVQGLASRNIVKIAAHSDGHHYLALAATGEVYSWGCGDGGRLGHGDTVPLEE 537

Query: 247 PKMIDALS 270
           PK+I A S
Sbjct: 538 PKVISAFS 545



 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 25/86 (29%), Positives = 43/86 (50%)
 Frame = +1

Query: 10   GEDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFS 189
            G  G +YGWG N  GQ+G  +      P         + VQ+  G +   A+T +  +++
Sbjct: 3949 GGSGTIYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLYA 4008

Query: 190  WGRGASGQLGHGEIIDRNTPKMIDAL 267
             G GA G+LG G     +TP +++++
Sbjct: 4009 TGYGAGGRLGIGGTESVSTPTLLESI 4034



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 33/119 (27%), Positives = 51/119 (42%), Gaps = 6/119 (5%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFP------DEQKIVQVACGWRHTLALTEN 174
           +DG++Y WG       G    + H +   V +P        +K++ VA G  H LALTE+
Sbjct: 674 KDGQVYSWG------KGDNQRLGHGTEEHVRYPKLLEGLQGKKVIDVAAGSTHCLALTED 727

Query: 175 KNIFSWGRGASGQLGHGEIIDRNTPKMIDALSLDGSACKQLESSNVVPMTVKVWVSPSE 351
             + SW  G++ Q  H + +    P   +  +L G   K +      P     W S SE
Sbjct: 728 SEVHSW--GSNDQCQHFDTLRVTKP---EPAALPGLDTKHIVGIACGPAQSFAWSSCSE 781



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 22/55 (40%), Positives = 30/55 (54%)
 Frame = +1

Query: 13   EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENK 177
            EDG++Y WG N  GQ+G         P  V     +K+ +VACG  HTLA + +K
Sbjct: 4266 EDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKVNRVACGSAHTLAWSTSK 4320

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>HERC2_MOUSE (Q4U2R1) HECT domain and RCC1-like domain-containing protein 2|
          Length = 4836

 Score = 66.2 bits (160), Expect = 4e-11
 Identities = 36/89 (40%), Positives = 50/89 (56%), Gaps = 2/89 (2%)
 Frame = +1

Query: 19   GKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWR--HTLALTENKNIFSW 192
            G+LY WG  ++G++G  DN     P  V      +++QVACG R   TLALT+   +FSW
Sbjct: 3119 GELYTWGLGEYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSW 3178

Query: 193  GRGASGQLGHGEIIDRNTPKMIDALSLDG 279
            G G  G+LG G     N P+ I+ L+  G
Sbjct: 3179 GDGDFGKLGRGGSEGCNIPQNIERLNGQG 3207



 Score = 65.9 bits (159), Expect = 5e-11
 Identities = 46/145 (31%), Positives = 66/145 (45%), Gaps = 3/145 (2%)
 Frame = +1

Query: 16  DGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGW--RHTLALTENKNIFS 189
           +G+LY WG   +G++G   + D   P+ V      K++ VACG     TLA+TEN  ++S
Sbjct: 570 EGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTENGQVWS 629

Query: 190 WGRGASGQLGHGEIIDRNTPKMIDAL-SLDGSACKQLESSNVVPMTVKVWVSPSERFALV 366
           WG G  G+LG G      TPK+I+ L  LD                +KV        AL 
Sbjct: 630 WGDGDYGKLGRGGSDGCKTPKLIEKLQDLD---------------VIKVRCGSQFSIALT 674

Query: 367 PDENVCKSGNGTDKHAPEGDAKRMR 441
            D  V   G G ++    G  + +R
Sbjct: 675 KDGQVYSWGKGDNQRLGHGTEEHVR 699



 Score = 60.1 bits (144), Expect = 3e-09
 Identities = 30/86 (34%), Positives = 46/86 (53%), Gaps = 2/86 (2%)
 Frame = +1

Query: 19   GKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGW--RHTLALTENKNIFSW 192
            G LY WG  ++G++G  D+ D   P  V      +++ +ACG     TL LT++  ++SW
Sbjct: 4112 GDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQGHRVIDIACGSGDAQTLCLTDDDTVWSW 4171

Query: 193  GRGASGQLGHGEIIDRNTPKMIDALS 270
            G G  G+LG G       P  ID+L+
Sbjct: 4172 GDGDYGKLGRGGSDGCKVPMKIDSLT 4197



 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 26/86 (30%), Positives = 52/86 (60%), Gaps = 1/86 (1%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHC-SPVEVNFPDEQKIVQVACGWRHTLALTENKNIFS 189
           E+G+++ WG   +G++G     D C +P  +    +  +++V CG + ++ALT++  ++S
Sbjct: 623 ENGQVWSWGDGDYGKLG-RGGSDGCKTPKLIEKLQDLDVIKVRCGSQFSIALTKDGQVYS 681

Query: 190 WGRGASGQLGHGEIIDRNTPKMIDAL 267
           WG+G + +LGHG       PK+++ L
Sbjct: 682 WGKGDNQRLGHGTEEHVRYPKLLEGL 707



 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 29/87 (33%), Positives = 47/87 (54%), Gaps = 4/87 (4%)
 Frame = +1

Query: 19  GKLYGWGWNKFGQVGVEDNVDHCSPVEVN-FPDEQK---IVQVACGWRHTLALTENKNIF 186
           G++Y WG    G++G  D V    P  ++ F  +Q    +V +ACG  ++ A+T    ++
Sbjct: 515 GEVYSWGCGDGGRLGHGDTVPLEEPKVISAFSGKQAGKHVVHIACGSTYSAAITAEGELY 574

Query: 187 SWGRGASGQLGHGEIIDRNTPKMIDAL 267
           +WGRG  G+LGHG   D   P ++  L
Sbjct: 575 TWGRGNYGRLGHGSSEDEAIPMLVAGL 601



 Score = 55.1 bits (131), Expect = 9e-08
 Identities = 26/88 (29%), Positives = 49/88 (55%)
 Frame = +1

Query: 4    ARGEDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNI 183
            A   +G++Y WG  + G++G  +      P  +      ++V VA G  H+  +T   ++
Sbjct: 4055 ALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDL 4114

Query: 184  FSWGRGASGQLGHGEIIDRNTPKMIDAL 267
            ++WG+G  G+LGH +  D+  PK+++AL
Sbjct: 4115 YTWGKGRYGRLGHSDSEDQLKPKLVEAL 4142



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 26/84 (30%), Positives = 45/84 (53%)
 Frame = +1

Query: 16   DGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWG 195
            DGK++ WG    G++G    ++   P  +     ++I  +A G  H+  LT +  +++WG
Sbjct: 3066 DGKVFSWGEGDDGKLGHFSRMNCDKPRLIQALKTKRIRDIAYGSSHSAPLTSSGELYTWG 3125

Query: 196  RGASGQLGHGEIIDRNTPKMIDAL 267
             G  G+LGHG+   +  PKM+  L
Sbjct: 3126 LGEYGRLGHGDNTTQLKPKMVKVL 3149



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 24/85 (28%), Positives = 49/85 (57%)
 Frame = +1

Query: 13   EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSW 192
            ++G ++ WG   FG++G   +     P  +   + Q + Q+ CG + +LALT++  +++W
Sbjct: 3171 DEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTW 3230

Query: 193  GRGASGQLGHGEIIDRNTPKMIDAL 267
            G+G   +LGHG  +    P++++ L
Sbjct: 3231 GKGDYFRLGHGSDVHVRKPQVVEGL 3255



 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 28/86 (32%), Positives = 45/86 (52%), Gaps = 2/86 (2%)
 Frame = +1

Query: 16   DGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVAC--GWRHTLALTENKNIFS 189
            DGKLY  G+   G++G+       +P  +       I +VA   G +H LAL+    ++S
Sbjct: 4005 DGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYS 4064

Query: 190  WGRGASGQLGHGEIIDRNTPKMIDAL 267
            WG    G+LGHG     + P++I++L
Sbjct: 4065 WGEAEDGKLGHGNRSPCDRPRVIESL 4090



 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 24/86 (27%), Positives = 48/86 (55%), Gaps = 1/86 (1%)
 Frame = +1

Query: 13   EDGKLYGWGWNKFGQVGVEDNVDHCS-PVEVNFPDEQKIVQVACGWRHTLALTENKNIFS 189
            +D  ++ WG   +G++G     D C  P++++      +V+V CG + ++ALT++  +++
Sbjct: 4164 DDDTVWSWGDGDYGKLG-RGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYT 4222

Query: 190  WGRGASGQLGHGEIIDRNTPKMIDAL 267
            WG+G   +LGHG       P+ +  L
Sbjct: 4223 WGKGDYHRLGHGSDDHVRRPRQVQGL 4248



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 31/112 (27%), Positives = 50/112 (44%)
 Frame = +1

Query: 13   EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSW 192
            + G ++ WG   + ++G   +V    P  V     +KIV VA G  H LA+T++  +++W
Sbjct: 3223 KSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAW 3282

Query: 193  GRGASGQLGHGEIIDRNTPKMIDALSLDGSACKQLESSNVVPMTVKVWVSPS 348
            G    GQ G+G       P ++  L           SS+ V  T     +PS
Sbjct: 3283 GDNDHGQQGNGTTTVNRKPTLVQGLEGQKITRVACGSSHSVAWTTVDVATPS 3334



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 26/68 (38%), Positives = 36/68 (52%)
 Frame = +1

Query: 121  KIVQVACGWRHTLALTENKNIFSWGRGASGQLGHGEIIDRNTPKMIDALSLDGSACKQLE 300
            K V V  G RH  ALT +  +FSWG G  G+LGH   ++ + P++I AL           
Sbjct: 3049 KKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIQALKTKRIRDIAYG 3108

Query: 301  SSNVVPMT 324
            SS+  P+T
Sbjct: 3109 SSHSAPLT 3116



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 23/85 (27%), Positives = 42/85 (49%)
 Frame = +1

Query: 13   EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSW 192
            + G +Y WG   + ++G   +     P +V     +K++ +A G  H +  TE+  +++W
Sbjct: 4216 KSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTW 4275

Query: 193  GRGASGQLGHGEIIDRNTPKMIDAL 267
            G    GQLG G       P+++ AL
Sbjct: 4276 GDNDEGQLGDGTTNAIQRPRLVAAL 4300



 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 25/68 (36%), Positives = 35/68 (51%), Gaps = 2/68 (2%)
 Frame = +1

Query: 73  NVDHCSPVEVNFPDEQKIVQVAC--GWRHTLALTENKNIFSWGRGASGQLGHGEIIDRNT 246
           N D  +P  V     + IV++A      H LAL     ++SWG G  G+LGHG+ +    
Sbjct: 479 NSDMLAPQLVQGLASRNIVKIAAHSDGHHYLALAATGEVYSWGCGDGGRLGHGDTVPLEE 538

Query: 247 PKMIDALS 270
           PK+I A S
Sbjct: 539 PKVISAFS 546



 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 25/86 (29%), Positives = 43/86 (50%)
 Frame = +1

Query: 10   GEDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFS 189
            G  G +YGWG N  GQ+G  +      P         + VQ+  G +   A+T +  +++
Sbjct: 3951 GGSGTIYGWGHNHRGQLGGIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTADGKLYA 4010

Query: 190  WGRGASGQLGHGEIIDRNTPKMIDAL 267
             G GA G+LG G     +TP +++++
Sbjct: 4011 TGYGAGGRLGIGGTESVSTPTLLESI 4036



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 29/108 (26%), Positives = 49/108 (45%), Gaps = 11/108 (10%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFP------DEQKIVQVACGWRHTLALTEN 174
           +DG++Y WG       G    + H +   V +P        +K++ VA G  H L LTE+
Sbjct: 675 KDGQVYSWG------KGDNQRLGHGTEEHVRYPKLLEGLQGKKVIDVAAGSTHCLVLTED 728

Query: 175 KNIFSWGRGASGQLGHGEIIDRNTPKM-----IDALSLDGSACKQLES 303
             + SW  G++ Q  H + +    P+      +D+  + G AC   +S
Sbjct: 729 SEVHSW--GSNDQCQHFDTLGVTKPEPTAFPGLDSKHIVGIACGPAQS 774



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 22/55 (40%), Positives = 30/55 (54%)
 Frame = +1

Query: 13   EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENK 177
            EDG++Y WG N  GQ+G         P  V     +K+ +VACG  HTLA + +K
Sbjct: 4268 EDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKVNRVACGSAHTLAWSTSK 4322

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>RCBT2_RAT (Q6P798) RCC1 and BTB domain-containing protein 2 (Regulator of|
           chromosome condensation and BTB domain-containing
           protein 2) (Chromosome condensation 1-like)
          Length = 551

 Score = 62.4 bits (150), Expect = 6e-10
 Identities = 28/79 (35%), Positives = 48/79 (60%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSW 192
           + G++Y WG+N  GQ+G+  + +  +P  V      ++ +VACG+ HTL LT+   I++W
Sbjct: 222 DTGEVYVWGYNGNGQLGLGSSGNQPTPCRVAALQGIRVQRVACGYAHTLVLTDEGQIYAW 281

Query: 193 GRGASGQLGHGEIIDRNTP 249
           G  + GQLG G   +++ P
Sbjct: 282 GANSYGQLGTGNKSNQSYP 300



 Score = 58.5 bits (140), Expect = 8e-09
 Identities = 36/114 (31%), Positives = 58/114 (50%), Gaps = 7/114 (6%)
 Frame = +1

Query: 16  DGKLYGWGWNKFGQVGVEDNVDHCSP--VEVNFPDEQKIVQVACGWRHTLALTENKNIFS 189
           DG+++ WG N + Q+G         P  +  N  ++Q +++VACG  H+L LT +  +F+
Sbjct: 117 DGEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQ-VIEVACGSYHSLVLTSDGEVFA 175

Query: 190 WGRGASGQLGHGEIIDRNTPKMIDALSLD----GSACKQLESSNVVPM-TVKVW 336
           WG   SGQ+G G   ++  P+ +     +      AC Q+ S  VV    V VW
Sbjct: 176 WGYNNSGQVGSGSTANQPIPRRVTGCLQNKVVMSIACGQMCSMAVVDTGEVYVW 229



 Score = 55.5 bits (132), Expect = 7e-08
 Identities = 28/85 (32%), Positives = 46/85 (54%), Gaps = 1/85 (1%)
 Frame = +1

Query: 16  DGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQ-VACGWRHTLALTENKNIFSW 192
           DG+++ WG+N  GQVG     +   P  V    + K+V  +ACG   ++A+ +   ++ W
Sbjct: 170 DGEVFAWGYNNSGQVGSGSTANQPIPRRVTGCLQNKVVMSIACGQMCSMAVVDTGEVYVW 229

Query: 193 GRGASGQLGHGEIIDRNTPKMIDAL 267
           G   +GQLG G   ++ TP  + AL
Sbjct: 230 GYNGNGQLGLGSSGNQPTPCRVAAL 254



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 23/73 (31%), Positives = 38/73 (52%), Gaps = 3/73 (4%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHT-LALTENKNIFS 189
           ++G++Y WG N +GQ+G  +  +   P  V    ++ I   AC   HT  A ++  +++ 
Sbjct: 274 DEGQIYAWGANSYGQLGTGNKSNQSYPTPVVVEKDRIIEIAACHSAHTSAAKSQGGHVYM 333

Query: 190 WG--RGASGQLGH 222
           WG  RG S  L H
Sbjct: 334 WGQCRGQSVILPH 346



 Score = 33.1 bits (74), Expect = 0.36
 Identities = 20/69 (28%), Positives = 34/69 (49%), Gaps = 1/69 (1%)
 Frame = +1

Query: 22  KLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACG-WRHTLALTENKNIFSWGR 198
           +++  G N  G +GV D      P  ++    +KI  ++ G   H +  T +  +F+WG 
Sbjct: 66  EIFVLGTNCSGCLGVGDIQSTIEPRRLDSLTGKKIASLSYGSGPHIVLATTDGEVFTWGH 125

Query: 199 GASGQLGHG 225
            A  QLG+G
Sbjct: 126 NAYSQLGNG 134

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>RCBT2_PONPY (Q5RCZ7) RCC1 and BTB domain-containing protein 2 (Regulator of|
           chromosome condensation and BTB domain-containing
           protein 2)
          Length = 551

 Score = 62.4 bits (150), Expect = 6e-10
 Identities = 27/79 (34%), Positives = 49/79 (62%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSW 192
           + G++Y WG+N  GQ+G+ ++ +  +P  V      ++ +VACG+ HTL LT+   +++W
Sbjct: 222 DTGEVYVWGYNGNGQLGLGNSGNQPTPCRVAALQGIRVQRVACGYAHTLVLTDEGQVYAW 281

Query: 193 GRGASGQLGHGEIIDRNTP 249
           G  + GQLG G   +++ P
Sbjct: 282 GANSYGQLGTGNKSNQSYP 300



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 26/83 (31%), Positives = 48/83 (57%), Gaps = 2/83 (2%)
 Frame = +1

Query: 16  DGKLYGWGWNKFGQVGVEDNVDHCSP--VEVNFPDEQKIVQVACGWRHTLALTENKNIFS 189
           +G+++ WG N + Q+G         P  +  N  ++Q +++VACG  H+L LT +  +F+
Sbjct: 117 EGEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQ-VIEVACGSYHSLVLTSDGEVFA 175

Query: 190 WGRGASGQLGHGEIIDRNTPKMI 258
           WG   SGQ+G G  +++  P+ +
Sbjct: 176 WGYNNSGQVGSGSTVNQPIPRRV 198



 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 29/85 (34%), Positives = 46/85 (54%), Gaps = 1/85 (1%)
 Frame = +1

Query: 16  DGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIV-QVACGWRHTLALTENKNIFSW 192
           DG+++ WG+N  GQVG    V+   P  V    + K+V  +ACG    +A+ +   ++ W
Sbjct: 170 DGEVFAWGYNNSGQVGSGSTVNQPIPRRVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVW 229

Query: 193 GRGASGQLGHGEIIDRNTPKMIDAL 267
           G   +GQLG G   ++ TP  + AL
Sbjct: 230 GYNGNGQLGLGNSGNQPTPCRVAAL 254



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 24/73 (32%), Positives = 38/73 (52%), Gaps = 3/73 (4%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHT-LALTENKNIFS 189
           ++G++Y WG N +GQ+G  +  +   P  V    ++ I   AC   HT  A T+  +++ 
Sbjct: 274 DEGQVYAWGANSYGQLGTGNKSNQSYPTPVTVEKDRIIEIAACHSTHTSAAKTQGGHVYM 333

Query: 190 WG--RGASGQLGH 222
           WG  RG S  L H
Sbjct: 334 WGQCRGQSVILPH 346



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 19/69 (27%), Positives = 34/69 (49%), Gaps = 1/69 (1%)
 Frame = +1

Query: 22  KLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACG-WRHTLALTENKNIFSWGR 198
           +++  G N  G +G+ D      P  ++  + +KI  ++ G   H +  T    +F+WG 
Sbjct: 66  EIFVLGTNCCGCLGLGDVQSTIEPRRLDSLNGKKIACLSYGSGPHIVLATTEGEVFTWGH 125

Query: 199 GASGQLGHG 225
            A  QLG+G
Sbjct: 126 NAYSQLGNG 134

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>RCBT2_MOUSE (Q99LJ7) RCC1 and BTB domain-containing protein 2 (Regulator of|
           chromosome condensation and BTB domain-containing
           protein 2) (Chromosome condensation 1-like)
          Length = 551

 Score = 62.4 bits (150), Expect = 6e-10
 Identities = 28/79 (35%), Positives = 48/79 (60%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSW 192
           + G++Y WG+N  GQ+G+  + +  +P  V      ++ +VACG+ HTL LT+   I++W
Sbjct: 222 DTGEVYVWGYNGNGQLGLGSSGNQPTPCRVAALQGIRVQRVACGYAHTLVLTDEGQIYAW 281

Query: 193 GRGASGQLGHGEIIDRNTP 249
           G  + GQLG G   +++ P
Sbjct: 282 GANSYGQLGTGNKSNQSYP 300



 Score = 58.5 bits (140), Expect = 8e-09
 Identities = 36/114 (31%), Positives = 58/114 (50%), Gaps = 7/114 (6%)
 Frame = +1

Query: 16  DGKLYGWGWNKFGQVGVEDNVDHCSP--VEVNFPDEQKIVQVACGWRHTLALTENKNIFS 189
           DG+++ WG N + Q+G         P  +  N  ++Q +++VACG  H+L LT +  +F+
Sbjct: 117 DGEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQ-VIEVACGSYHSLVLTSDGEVFA 175

Query: 190 WGRGASGQLGHGEIIDRNTPKMIDALSLD----GSACKQLESSNVVPM-TVKVW 336
           WG   SGQ+G G   ++  P+ +     +      AC Q+ S  VV    V VW
Sbjct: 176 WGYNNSGQVGSGSTANQPIPRRVTGCLQNKVVMNIACGQMCSMAVVDTGEVYVW 229



 Score = 55.5 bits (132), Expect = 7e-08
 Identities = 28/85 (32%), Positives = 46/85 (54%), Gaps = 1/85 (1%)
 Frame = +1

Query: 16  DGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQ-VACGWRHTLALTENKNIFSW 192
           DG+++ WG+N  GQVG     +   P  V    + K+V  +ACG   ++A+ +   ++ W
Sbjct: 170 DGEVFAWGYNNSGQVGSGSTANQPIPRRVTGCLQNKVVMNIACGQMCSMAVVDTGEVYVW 229

Query: 193 GRGASGQLGHGEIIDRNTPKMIDAL 267
           G   +GQLG G   ++ TP  + AL
Sbjct: 230 GYNGNGQLGLGSSGNQPTPCRVAAL 254



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 24/73 (32%), Positives = 38/73 (52%), Gaps = 3/73 (4%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHT-LALTENKNIFS 189
           ++G++Y WG N +GQ+G  +  +   P  V    ++ I   AC   HT  A T+  +++ 
Sbjct: 274 DEGQIYAWGANSYGQLGTGNKSNQSYPTPVVVEKDRIIEIAACHSAHTSAAKTQGGHVYM 333

Query: 190 WG--RGASGQLGH 222
           WG  RG S  L H
Sbjct: 334 WGQCRGQSVILPH 346



 Score = 33.1 bits (74), Expect = 0.36
 Identities = 20/69 (28%), Positives = 34/69 (49%), Gaps = 1/69 (1%)
 Frame = +1

Query: 22  KLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACG-WRHTLALTENKNIFSWGR 198
           +++  G N  G +GV D      P  ++    +KI  ++ G   H +  T +  +F+WG 
Sbjct: 66  EIFVLGTNCSGCLGVGDIQSTIEPRRLDSLTGKKIASLSYGSGPHIVLATTDGEVFTWGH 125

Query: 199 GASGQLGHG 225
            A  QLG+G
Sbjct: 126 NAYSQLGNG 134

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>RCBT2_HUMAN (O95199) RCC1 and BTB domain-containing protein 2 (Regulator of|
           chromosome condensation and BTB domain-containing
           protein 2) (Chromosome condensation 1-like) (CHC1-L)
           (RCC1-like G exchanging factor)
          Length = 551

 Score = 62.4 bits (150), Expect = 6e-10
 Identities = 27/79 (34%), Positives = 49/79 (62%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSW 192
           + G++Y WG+N  GQ+G+ ++ +  +P  V      ++ +VACG+ HTL LT+   +++W
Sbjct: 222 DTGEVYVWGYNGNGQLGLGNSGNQPTPCRVAALQGIRVQRVACGYAHTLVLTDEGQVYAW 281

Query: 193 GRGASGQLGHGEIIDRNTP 249
           G  + GQLG G   +++ P
Sbjct: 282 GANSYGQLGTGNKSNQSYP 300



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 26/83 (31%), Positives = 48/83 (57%), Gaps = 2/83 (2%)
 Frame = +1

Query: 16  DGKLYGWGWNKFGQVGVEDNVDHCSP--VEVNFPDEQKIVQVACGWRHTLALTENKNIFS 189
           +G+++ WG N + Q+G         P  +  N  ++Q +++VACG  H+L LT +  +F+
Sbjct: 117 EGEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQ-VIEVACGSYHSLVLTSDGEVFA 175

Query: 190 WGRGASGQLGHGEIIDRNTPKMI 258
           WG   SGQ+G G  +++  P+ +
Sbjct: 176 WGYNNSGQVGSGSTVNQPIPRRV 198



 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 29/85 (34%), Positives = 46/85 (54%), Gaps = 1/85 (1%)
 Frame = +1

Query: 16  DGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIV-QVACGWRHTLALTENKNIFSW 192
           DG+++ WG+N  GQVG    V+   P  V    + K+V  +ACG    +A+ +   ++ W
Sbjct: 170 DGEVFAWGYNNSGQVGSGSTVNQPIPRRVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVW 229

Query: 193 GRGASGQLGHGEIIDRNTPKMIDAL 267
           G   +GQLG G   ++ TP  + AL
Sbjct: 230 GYNGNGQLGLGNSGNQPTPCRVAAL 254



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 24/73 (32%), Positives = 38/73 (52%), Gaps = 3/73 (4%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHT-LALTENKNIFS 189
           ++G++Y WG N +GQ+G  +  +   P  V    ++ I   AC   HT  A T+  +++ 
Sbjct: 274 DEGQVYAWGANSYGQLGTGNKSNQSYPTPVTVEKDRIIEIAACHSTHTSAAKTQGGHVYM 333

Query: 190 WG--RGASGQLGH 222
           WG  RG S  L H
Sbjct: 334 WGQCRGQSVILPH 346



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 19/69 (27%), Positives = 34/69 (49%), Gaps = 1/69 (1%)
 Frame = +1

Query: 22  KLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACG-WRHTLALTENKNIFSWGR 198
           +++  G N  G +G+ D      P  ++  + +KI  ++ G   H +  T    +F+WG 
Sbjct: 66  EIFVLGTNCCGCLGLGDVQSTIEPRRLDSLNGKKIACLSYGSGPHIVLATTEGEVFTWGH 125

Query: 199 GASGQLGHG 225
            A  QLG+G
Sbjct: 126 NAYSQLGNG 134

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>NEK9_MOUSE (Q8K1R7) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)|
           (NimA-related protein kinase 9) (Never in mitosis
           A-related kinase 9)
          Length = 984

 Score = 62.0 bits (149), Expect = 7e-10
 Identities = 30/85 (35%), Positives = 50/85 (58%), Gaps = 2/85 (2%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVE--DNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIF 186
           ++G+LY +G + +G +GV+     +   P+++NF     + QV+CG  H + LT NK ++
Sbjct: 443 DEGQLYAFGSDYYGCMGVDKVSGPEVLEPMQLNFFLSNPVEQVSCGDNHVVVLTRNKEVY 502

Query: 187 SWGRGASGQLGHGEIIDRNTPKMID 261
           SWG G  G+LG     D  TP+ +D
Sbjct: 503 SWGCGEYGRLGLDSEEDYYTPQRVD 527



 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 30/94 (31%), Positives = 51/94 (54%), Gaps = 8/94 (8%)
 Frame = +1

Query: 1   SARGEDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFP-DEQKIVQVACGWRHTLALTENK 177
           +A  E G+L  +G NK GQ+GV +         +  P   +++++V+CG   T+A T++ 
Sbjct: 610 AAIDERGRLLTFGCNKCGQLGVGNYKKRLGINLLGGPLGGKQVIRVSCGDEFTIAATDDN 669

Query: 178 NIFSWGRGASGQLG-------HGEIIDRNTPKMI 258
           +IF+WG G +G+L        HG  I  + P+ I
Sbjct: 670 HIFAWGNGGNGRLAMTPTERPHGSDICTSWPRPI 703



 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 20/66 (30%), Positives = 36/66 (54%)
 Frame = +1

Query: 22  KLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWGRG 201
           ++Y WG  ++G++G++   D+ +P  V+ P    IV V CG   T  LT++  + + G  
Sbjct: 500 EVYSWGCGEYGRLGLDSEEDYYTPQRVDVPKALIIVAVQCGCDGTFLLTQSGKVLACGLN 559

Query: 202 ASGQLG 219
              +LG
Sbjct: 560 EFNKLG 565



 Score = 34.7 bits (78), Expect = 0.12
 Identities = 22/90 (24%), Positives = 44/90 (48%), Gaps = 5/90 (5%)
 Frame = +1

Query: 22  KLYGW-----GWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIF 186
           +LY W     G    GQ+G  D   +  P  V     + I QV+CG   T+ +T+   ++
Sbjct: 389 ELYTWVNMQGGTKLHGQLGHGDKASYRQPKHVEKLQGKAIHQVSCGDDFTVCVTDEGQLY 448

Query: 187 SWGRGASGQLGHGEIIDRNTPKMIDALSLD 276
           ++G    G +G  ++   + P++++ + L+
Sbjct: 449 AFGSDYYGCMGVDKV---SGPEVLEPMQLN 475



 Score = 33.9 bits (76), Expect = 0.21
 Identities = 20/61 (32%), Positives = 28/61 (45%), Gaps = 5/61 (8%)
 Frame = +1

Query: 130 QVACGWRHTLALTENKNIFSW-----GRGASGQLGHGEIIDRNTPKMIDALSLDGSACKQ 294
           QV  G  H   +T  K +++W     G    GQLGHG+      PK ++   L G A  Q
Sbjct: 373 QVCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASYRQPKHVE--KLQGKAIHQ 430

Query: 295 L 297
           +
Sbjct: 431 V 431



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 13/84 (15%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVD--------HCSPVEVNFPDEQ-----KIVQVACGWRH 153
           + GK+   G N+F ++G+   +         H  P   +F   +     KI  +A G  H
Sbjct: 549 QSGKVLACGLNEFNKLGLNQCMSGIINHEAYHEVPYTTSFTLAKQLSFYKIRTIAPGKTH 608

Query: 154 TLALTENKNIFSWGRGASGQLGHG 225
           T A+ E   + ++G    GQLG G
Sbjct: 609 TAAIDERGRLLTFGCNKCGQLGVG 632

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>RCC2_BRARE (Q6NYE2) Protein RCC2 homolog|
          Length = 495

 Score = 62.0 bits (149), Expect = 7e-10
 Identities = 32/74 (43%), Positives = 42/74 (56%)
 Frame = +1

Query: 16  DGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWG 195
           +GKL+ WG N  GQ+G  D     +P  +    E+ IV  ACG  HTLALTEN  ++++G
Sbjct: 141 EGKLWSWGRNDKGQLGHGDTKRLEAPKLIEGLGEEVIVAAACGRNHTLALTENGTVYTFG 200

Query: 196 RGASGQLGHGEIID 237
               GQLG G   D
Sbjct: 201 ENKLGQLGQGNQTD 214



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 23/55 (41%), Positives = 29/55 (52%)
 Frame = +1

Query: 133 VACGWRHTLALTENKNIFSWGRGASGQLGHGEIIDRNTPKMIDALSLDGSACKQL 297
           VACG  HTL L   K +FSWG G  G+LGH E  D   P+++      G    Q+
Sbjct: 308 VACGANHTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPRLVKLFDFPGRGATQI 362



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 27/71 (38%), Positives = 42/71 (59%), Gaps = 1/71 (1%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHC-SPVEVNFPDEQKIVQVACGWRHTLALTENKNIFS 189
           E+G +Y +G NK GQ+G  +  D   SP  + + + Q IV+VACG   ++ +    N++S
Sbjct: 192 ENGTVYTFGENKLGQLGQGNQTDAVLSPATIQY-NGQPIVKVACGAEFSMIVDCKGNLYS 250

Query: 190 WGRGASGQLGH 222
           +G    GQLGH
Sbjct: 251 FGCPEYGQLGH 261



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 17/39 (43%), Positives = 24/39 (61%)
 Frame = +1

Query: 151 HTLALTENKNIFSWGRGASGQLGHGEIIDRNTPKMIDAL 267
           H+L +T    ++SWGR   GQLGHG+      PK+I+ L
Sbjct: 134 HSLIITTEGKLWSWGRNDKGQLGHGDTKRLEAPKLIEGL 172



 Score = 36.6 bits (83), Expect = 0.033
 Identities = 17/60 (28%), Positives = 32/60 (53%), Gaps = 2/60 (3%)
 Frame = +1

Query: 22  KLYGWGWNKFGQVGVEDNVDHCSPVEVNFPD--EQKIVQVACGWRHTLALTENKNIFSWG 195
           +++ WG+  +G++G  +  D   P  V   D   +   Q+ CG++ + AL+E   +F WG
Sbjct: 323 RVFSWGFGGYGRLGHAEQKDEMVPRLVKLFDFPGRGATQIYCGYQCSFALSEMGGLFFWG 382



 Score = 30.4 bits (67), Expect = 2.3
 Identities = 26/107 (24%), Positives = 46/107 (42%), Gaps = 9/107 (8%)
 Frame = +1

Query: 4   ARGEDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWR--------HTL 159
           A  E G L+ WG            V + S     +P   K VQ  CGW+         ++
Sbjct: 371 ALSEMGGLFFWG------------VTNTSRESTMYP---KAVQDLCGWKIRSLACGKSSI 415

Query: 160 ALTENKNIFSWGRGAS-GQLGHGEIIDRNTPKMIDALSLDGSACKQL 297
            +  + +  SWG   + G+LG+G+   +++    +  +LDG   +Q+
Sbjct: 416 IVAADDSTISWGPSPTFGELGYGDNKPKSSTTAQEVKTLDGVYSEQV 462

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>NEK9_HUMAN (Q8TD19) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)|
           (NimA-related protein kinase 9) (Never in mitosis
           A-related kinase 9) (Nercc1 kinase) (NIMA-related kinase
           8) (Nek8)
          Length = 979

 Score = 61.6 bits (148), Expect = 9e-10
 Identities = 30/85 (35%), Positives = 50/85 (58%), Gaps = 2/85 (2%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVED--NVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIF 186
           ++G+LY +G + +G +GV+     +   P+++NF     + QV+CG  H + LT NK ++
Sbjct: 443 DEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLNFFLSNPVEQVSCGDNHVVVLTRNKEVY 502

Query: 187 SWGRGASGQLGHGEIIDRNTPKMID 261
           SWG G  G+LG     D  TP+ +D
Sbjct: 503 SWGCGEYGRLGLDSEEDYYTPQKVD 527



 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 30/94 (31%), Positives = 51/94 (54%), Gaps = 8/94 (8%)
 Frame = +1

Query: 1   SARGEDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFP-DEQKIVQVACGWRHTLALTENK 177
           +A  E G+L  +G NK GQ+GV +         +  P   +++++V+CG   T+A T++ 
Sbjct: 610 AAIDERGRLLTFGCNKCGQLGVGNYKKRLGINLLGGPLGGKQVIRVSCGDEFTIAATDDN 669

Query: 178 NIFSWGRGASGQLG-------HGEIIDRNTPKMI 258
           +IF+WG G +G+L        HG  I  + P+ I
Sbjct: 670 HIFAWGNGGNGRLAMTPTERPHGSDICTSWPRPI 703



 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 20/66 (30%), Positives = 37/66 (56%)
 Frame = +1

Query: 22  KLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWGRG 201
           ++Y WG  ++G++G++   D+ +P +V+ P    IV V CG   T  LT++  + + G  
Sbjct: 500 EVYSWGCGEYGRLGLDSEEDYYTPQKVDVPKALIIVAVQCGCDGTFLLTQSGKVLACGLN 559

Query: 202 ASGQLG 219
              +LG
Sbjct: 560 EFNKLG 565



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 22/90 (24%), Positives = 43/90 (47%), Gaps = 5/90 (5%)
 Frame = +1

Query: 22  KLYGW-----GWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIF 186
           +LY W     G    GQ+G  D   +  P  V     + I QV+CG   T+ +T+   ++
Sbjct: 389 ELYTWVNMQGGTKLHGQLGHGDKASYRQPKHVEKLQGKAIHQVSCGDDFTVCVTDEGQLY 448

Query: 187 SWGRGASGQLGHGEIIDRNTPKMIDALSLD 276
           ++G    G +G  ++     P++++ + L+
Sbjct: 449 AFGSDYYGCMGVDKVAG---PEVLEPMQLN 475



 Score = 33.9 bits (76), Expect = 0.21
 Identities = 20/61 (32%), Positives = 28/61 (45%), Gaps = 5/61 (8%)
 Frame = +1

Query: 130 QVACGWRHTLALTENKNIFSW-----GRGASGQLGHGEIIDRNTPKMIDALSLDGSACKQ 294
           QV  G  H   +T  K +++W     G    GQLGHG+      PK ++   L G A  Q
Sbjct: 373 QVCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASYRQPKHVE--KLQGKAIHQ 430

Query: 295 L 297
           +
Sbjct: 431 V 431



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 13/84 (15%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVD--------HCSPVEVNFPDEQ-----KIVQVACGWRH 153
           + GK+   G N+F ++G+   +         H  P   +F   +     KI  +A G  H
Sbjct: 549 QSGKVLACGLNEFNKLGLNQCMSGIINHEAYHEVPYTTSFTLAKQLSFYKIRTIAPGKTH 608

Query: 154 TLALTENKNIFSWGRGASGQLGHG 225
           T A+ E   + ++G    GQLG G
Sbjct: 609 TAAIDERGRLLTFGCNKCGQLGVG 632

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>MYCB2_MOUSE (Q7TPH6) Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc|
            binding protein 2) (Protein associated with Myc)
            (Pam/highwire/rpm-1 protein)
          Length = 4711

 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 25/59 (42%), Positives = 39/59 (66%)
 Frame = +1

Query: 91   PVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWGRGASGQLGHGEIIDRNTPKMIDAL 267
            P  V F  E + VQV+CG+ H++ L EN +++++G G  GQLGHG++  R  P ++ AL
Sbjct: 893  PGSVRFDCELRAVQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHGDVNSRGCPTLVQAL 951



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 21/69 (30%), Positives = 32/69 (46%)
 Frame = +1

Query: 13   EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSW 192
            E+G +Y +G+ + GQ+G  D      P  V           AC   HT  L  +  +F++
Sbjct: 919  ENGDVYTFGYGQHGQLGHGDVNSRGCPTLVQALPGPSTQVTACS-NHTAVLLMDGQVFTF 977

Query: 193  GRGASGQLG 219
            G  + GQLG
Sbjct: 978  GSFSKGQLG 986



 Score = 29.6 bits (65), Expect = 4.0
 Identities = 21/73 (28%), Positives = 35/73 (47%)
 Frame = +1

Query: 1   SARGEDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKN 180
           S   +DG+LY +G +        D+    S ++ +F     + QVA G  HT  L +N  
Sbjct: 613 SVISKDGELYMFGKDAI----YSDSSSLVSDLKGHF-----VTQVAMGKAHTCVLMKNGE 663

Query: 181 IFSWGRGASGQLG 219
           ++++G    GQ G
Sbjct: 664 VWTFGVNNKGQCG 676

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>MYCB2_HUMAN (O75592) Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc|
            binding protein 2) (Protein associated with Myc)
            (Pam/highwire/rpm-1 protein)
          Length = 4641

 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 25/59 (42%), Positives = 39/59 (66%)
 Frame = +1

Query: 91   PVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWGRGASGQLGHGEIIDRNTPKMIDAL 267
            P  V F  E + VQV+CG+ H++ L EN +++++G G  GQLGHG++  R  P ++ AL
Sbjct: 893  PGSVRFDCELRAVQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHGDVNSRGCPTLVQAL 951



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 23/70 (32%), Positives = 35/70 (50%), Gaps = 1/70 (1%)
 Frame = +1

Query: 13   EDGKLYGWGWNKFGQVGVED-NVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFS 189
            E+G +Y +G+ + GQ+G  D N   C  +    P      QV  G  HT  L  +  +F+
Sbjct: 919  ENGDVYTFGYGQHGQLGHGDVNSRGCPTLVQALPGPS--TQVTAGSNHTAVLLMDGQVFT 976

Query: 190  WGRGASGQLG 219
            +G  + GQLG
Sbjct: 977  FGSFSKGQLG 986



 Score = 28.5 bits (62), Expect = 8.9
 Identities = 20/73 (27%), Positives = 35/73 (47%)
 Frame = +1

Query: 1   SARGEDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKN 180
           S   +DG+LY +G +        D+    + ++ +F     + QVA G  HT  L +N  
Sbjct: 613 SVISKDGELYMFGKDAI----YSDSSSLVTDLKGHF-----VTQVAMGKAHTCVLMKNGE 663

Query: 181 IFSWGRGASGQLG 219
           ++++G    GQ G
Sbjct: 664 VWTFGVNNKGQCG 676

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>RCC2_HUMAN (Q9P258) Protein RCC2 (Telophase disk protein of 60 kDa) (RCC1-like|
           protein TD-60)
          Length = 522

 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 31/74 (41%), Positives = 42/74 (56%)
 Frame = +1

Query: 16  DGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWG 195
           +GKL+ WG N+ GQ+G  D     +P  +     + IV  ACG  HTLALTE  ++F++G
Sbjct: 168 EGKLWSWGRNEKGQLGHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAFG 227

Query: 196 RGASGQLGHGEIID 237
               GQLG G   D
Sbjct: 228 ENKMGQLGLGNQTD 241



 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 23/55 (41%), Positives = 29/55 (52%)
 Frame = +1

Query: 133 VACGWRHTLALTENKNIFSWGRGASGQLGHGEIIDRNTPKMIDALSLDGSACKQL 297
           VACG  HTL L   K +FSWG G  G+LGH E  D   P+++      G    Q+
Sbjct: 335 VACGANHTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPRLVKLFDFPGRGASQI 389



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 34/128 (26%), Positives = 64/128 (50%), Gaps = 5/128 (3%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHC-SPVEVNFPDEQKIVQVACGWRHTLALTENKNIFS 189
           E G ++ +G NK GQ+G+ +  D   SP ++ + + Q I ++ACG   ++ +    N++S
Sbjct: 219 ETGSVFAFGENKMGQLGLGNQTDAVPSPAQIMY-NGQPITKMACGAEFSMIMDCKGNLYS 277

Query: 190 WGRGASGQLGH---GEIIDRNTPKMIDALSLDGSACKQLE-SSNVVPMTVKVWVSPSERF 357
           +G    GQLGH   G+ I R                +++E    +VP  V +++  ++  
Sbjct: 278 FGCPEYGQLGHNSDGKFIAR---------------AQRIEYDCELVPRRVAIFIEKTKDG 322

Query: 358 ALVPDENV 381
            ++P  NV
Sbjct: 323 QILPVPNV 330



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 19/49 (38%), Positives = 29/49 (59%)
 Frame = +1

Query: 124 IVQVACGWRHTLALTENKNIFSWGRGASGQLGHGEIIDRNTPKMIDALS 270
           +V  +C   H+L +T    ++SWGR   GQLGHG+      P++I+ LS
Sbjct: 153 VVSGSCA-AHSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEGLS 200



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 18/68 (26%), Positives = 35/68 (51%), Gaps = 9/68 (13%)
 Frame = +1

Query: 121 KIVQVACGWR--------HTLALTENKNIFSWGRGAS-GQLGHGEIIDRNTPKMIDALSL 273
           K VQ  CGWR         ++ +  +++  SWG   + G+LG+G+   +++    +  +L
Sbjct: 422 KAVQDLCGWRIRSLACGKSSIIVAADESTISWGPSPTFGELGYGDHKPKSSTAAQEVKTL 481

Query: 274 DGSACKQL 297
           DG   +Q+
Sbjct: 482 DGIFSEQV 489

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>HERC5_HUMAN (Q9UII4) HECT domain and RCC1-like domain-containing protein 5|
           (Cyclin-E-binding protein 1)
          Length = 1024

 Score = 59.3 bits (142), Expect = 5e-09
 Identities = 29/83 (34%), Positives = 44/83 (53%)
 Frame = +1

Query: 19  GKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWGR 198
           G +Y WG N+ GQ+G+        P  +   D QK+  VACG  H+  LT++  +F++G 
Sbjct: 210 GNIYSWGKNECGQLGLGHTESKDDPSLIEGLDNQKVEFVACGGSHSALLTQDGLLFTFGA 269

Query: 199 GASGQLGHGEIIDRNTPKMIDAL 267
           G  GQLGH    +   P ++  L
Sbjct: 270 GKHGQLGHNSTQNELRPCLVAEL 292



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 30/89 (33%), Positives = 48/89 (53%), Gaps = 1/89 (1%)
 Frame = +1

Query: 4   ARGEDGKLYGWGWNKFGQVGVEDNVDHCS-PVEVNFPDEQKIVQVACGWRHTLALTENKN 180
           A  + G+L+ WG N  GQ+GV       + P  V       + Q++ G  H++AL+ + N
Sbjct: 152 ALSKGGELFAWGQNLHGQLGVGRKFPSTTTPQIVEHLAGVPLAQISAGEAHSMALSMSGN 211

Query: 181 IFSWGRGASGQLGHGEIIDRNTPKMIDAL 267
           I+SWG+   GQLG G    ++ P +I+ L
Sbjct: 212 IYSWGKNECGQLGLGHTESKDDPSLIEGL 240



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 29/80 (36%), Positives = 44/80 (55%), Gaps = 1/80 (1%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLA-LTENKNIFS 189
           +DG L+ +G  K GQ+G     +   P  V      ++ Q+ACG  HTLA +++   +FS
Sbjct: 260 QDGLLFTFGAGKHGQLGHNSTQNELRPCLVAELVGYRVTQIACGRWHTLAYVSDLGKVFS 319

Query: 190 WGRGASGQLGHGEIIDRNTP 249
           +G G  GQLG+G   D+  P
Sbjct: 320 FGSGKDGQLGNGGTRDQLMP 339



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 21/53 (39%), Positives = 36/53 (67%), Gaps = 1/53 (1%)
 Frame = +1

Query: 115 EQKIVQVACGWRHTLALTENKNIFSWGRGASGQLGHG-EIIDRNTPKMIDALS 270
           E+KI+Q+ CG  H+LAL++   +F+WG+   GQLG G +     TP++++ L+
Sbjct: 137 EKKIIQITCGDYHSLALSKGGELFAWGQNLHGQLGVGRKFPSTTTPQIVEHLA 189

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>RCC2_MOUSE (Q8BK67) Protein RCC2|
          Length = 520

 Score = 58.5 bits (140), Expect = 8e-09
 Identities = 30/74 (40%), Positives = 42/74 (56%)
 Frame = +1

Query: 16  DGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWG 195
           +GKL+ WG N+ GQ+G  D     +P  +     + IV  ACG  HTLALT+  ++F++G
Sbjct: 166 EGKLWSWGRNEKGQLGHGDTKRVEAPRLIEALSHEAIVLAACGRNHTLALTDTGSVFAFG 225

Query: 196 RGASGQLGHGEIID 237
               GQLG G   D
Sbjct: 226 ENKMGQLGLGNQTD 239



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 23/55 (41%), Positives = 29/55 (52%)
 Frame = +1

Query: 133 VACGWRHTLALTENKNIFSWGRGASGQLGHGEIIDRNTPKMIDALSLDGSACKQL 297
           VACG  HTL L   K +FSWG G  G+LGH E  D   P+++      G    Q+
Sbjct: 333 VACGANHTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPRLVKLFDFPGRGATQI 387



 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 33/128 (25%), Positives = 64/128 (50%), Gaps = 5/128 (3%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHC-SPVEVNFPDEQKIVQVACGWRHTLALTENKNIFS 189
           + G ++ +G NK GQ+G+ +  D   SP ++ + + Q I ++ACG   ++ +    N++S
Sbjct: 217 DTGSVFAFGENKMGQLGLGNQTDAVPSPAQIMY-NGQPITKMACGAEFSMLMDCKGNLYS 275

Query: 190 WGRGASGQLGH---GEIIDRNTPKMIDALSLDGSACKQLE-SSNVVPMTVKVWVSPSERF 357
           +G    GQLGH   G+ I R                +++E    +VP  V +++  ++  
Sbjct: 276 FGCPEYGQLGHNSDGKFIAR---------------AQRIEYDCELVPRRVAIFIEKTKDG 320

Query: 358 ALVPDENV 381
            ++P  NV
Sbjct: 321 QILPVPNV 328



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 20/49 (40%), Positives = 30/49 (61%)
 Frame = +1

Query: 124 IVQVACGWRHTLALTENKNIFSWGRGASGQLGHGEIIDRNTPKMIDALS 270
           +V  +C   H+L +T    ++SWGR   GQLGHG+      P++I+ALS
Sbjct: 151 VVSGSCA-AHSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEALS 198



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 18/68 (26%), Positives = 35/68 (51%), Gaps = 9/68 (13%)
 Frame = +1

Query: 121 KIVQVACGWR--------HTLALTENKNIFSWGRGAS-GQLGHGEIIDRNTPKMIDALSL 273
           K VQ  CGWR         ++ +  +++  SWG   + G+LG+G+   +++    +  +L
Sbjct: 420 KAVQDLCGWRIRSLACGKSSIIVAADESTISWGPSPTFGELGYGDHKPKSSTAAQEVKTL 479

Query: 274 DGSACKQL 297
           DG   +Q+
Sbjct: 480 DGIFSEQV 487

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>ALS2_MOUSE (Q920R0) Alsin (Amyotrophic lateral sclerosis protein 2 homolog)|
          Length = 1651

 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 25/69 (36%), Positives = 39/69 (56%)
 Frame = +1

Query: 22  KLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWGRG 201
           +++ WG  K GQ+G  D +    P+ V   D ++++ +  G  H+LALT    ++SWG  
Sbjct: 521 EVWTWGKGKEGQLGHGDVLPRLQPLCVKCLDGKEVIHLEAGGSHSLALTAKSQVYSWGSN 580

Query: 202 ASGQLGHGE 228
             GQLGH E
Sbjct: 581 TFGQLGHSE 589



 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 29/76 (38%), Positives = 41/76 (53%), Gaps = 7/76 (9%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQ-------KIVQVACGWRHTLALTE 171
           E G +Y WG N  GQ  V +      P  V+  D +       +I+Q+ACG  HTLAL+ 
Sbjct: 108 ESGVVYMWGENAAGQCAVANQQYVPEPSPVSISDSETSPSLAVRILQLACGEEHTLALSL 167

Query: 172 NKNIFSWGRGASGQLG 219
           ++ I++WG G   QLG
Sbjct: 168 SREIWAWGTGC--QLG 181



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 19/52 (36%), Positives = 31/52 (59%), Gaps = 2/52 (3%)
 Frame = +1

Query: 181 IFSWGRGASGQLGHGEIIDRNTPKMIDALSLDGSACKQLES--SNVVPMTVK 330
           +++WG+G  GQLGHG+++ R  P  +    LDG     LE+  S+ + +T K
Sbjct: 522 VWTWGKGKEGQLGHGDVLPRLQPLCVKC--LDGKEVIHLEAGGSHSLALTAK 571



 Score = 33.9 bits (76), Expect = 0.21
 Identities = 20/67 (29%), Positives = 35/67 (52%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSW 192
           EDG++Y +G   +     E  +   SP+  +      ++ VA G  H+ A+TE+  ++ W
Sbjct: 58  EDGEVYSFGTLPWKSESAE--ICPSSPLLESALVGHHVITVATGSFHSGAVTESGVVYMW 115

Query: 193 GRGASGQ 213
           G  A+GQ
Sbjct: 116 GENAAGQ 122

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>RCC2_XENLA (Q52KW8) Protein RCC2 homolog|
          Length = 513

 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 30/74 (40%), Positives = 40/74 (54%)
 Frame = +1

Query: 16  DGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWG 195
           +GKL+ WG N  GQ+G  D      P  +     +  V  ACG  HTLALTEN +++++G
Sbjct: 159 EGKLWSWGRNDKGQLGHGDIKRIDVPKLIESLKGEVFVHAACGRNHTLALTENGSVYAFG 218

Query: 196 RGASGQLGHGEIID 237
               GQLG G   D
Sbjct: 219 ENKMGQLGLGNKTD 232



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 21/55 (38%), Positives = 29/55 (52%)
 Frame = +1

Query: 133 VACGWRHTLALTENKNIFSWGRGASGQLGHGEIIDRNTPKMIDALSLDGSACKQL 297
           +ACG  H+L L   K +FSWG G  G+LGH E  D   P+++      G    Q+
Sbjct: 326 IACGINHSLILDSQKRVFSWGFGGYGRLGHSEQRDEMVPRLVKLFDFPGRGAAQI 380



 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 26/71 (36%), Positives = 43/71 (60%), Gaps = 1/71 (1%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHC-SPVEVNFPDEQKIVQVACGWRHTLALTENKNIFS 189
           E+G +Y +G NK GQ+G+ +  D   SP ++ + + Q I +VACG   ++ +    N++S
Sbjct: 210 ENGSVYAFGENKMGQLGLGNKTDAVPSPAQILY-NGQPITKVACGAEFSMIMDCKGNLYS 268

Query: 190 WGRGASGQLGH 222
           +G    GQLGH
Sbjct: 269 FGCPEYGQLGH 279



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 18/39 (46%), Positives = 27/39 (69%)
 Frame = +1

Query: 151 HTLALTENKNIFSWGRGASGQLGHGEIIDRNTPKMIDAL 267
           H+L +T    ++SWGR   GQLGHG+I   + PK+I++L
Sbjct: 152 HSLLITVEGKLWSWGRNDKGQLGHGDIKRIDVPKLIESL 190



 Score = 29.6 bits (65), Expect = 4.0
 Identities = 18/72 (25%), Positives = 35/72 (48%), Gaps = 9/72 (12%)
 Frame = +1

Query: 121 KIVQVACGWR--------HTLALTENKNIFSWGRGAS-GQLGHGEIIDRNTPKMIDALSL 273
           K VQ  CGW+         ++ +  +++  SWG   + G+LG+G+   +++    +  +L
Sbjct: 413 KAVQDLCGWKVRSLACGKSSIIVAADESTISWGPSPTFGELGYGDNKAKSSTTAQEVKTL 472

Query: 274 DGSACKQLESSN 309
           DG    Q+   N
Sbjct: 473 DGIYSDQVIMGN 484

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>NEK9_XENLA (Q7ZZC8) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)|
           (NimA-related protein kinase 9) (XNek9) (Nercc1 kinase)
          Length = 944

 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 28/85 (32%), Positives = 52/85 (61%), Gaps = 2/85 (2%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNV--DHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIF 186
           ++G+LY +G + +G +GV  +   +   P+ V+F   + + QV+CG  H +ALT +K+++
Sbjct: 425 DEGQLYSFGSDYYGCLGVNQSAGSEVLEPLLVDFFLNEPVDQVSCGDSHIMALTRSKSVY 484

Query: 187 SWGRGASGQLGHGEIIDRNTPKMID 261
           SWG G  G+LG     D  +P+ ++
Sbjct: 485 SWGCGEYGRLGLDSEDDVYSPQKVE 509



 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 27/73 (36%), Positives = 43/73 (58%), Gaps = 1/73 (1%)
 Frame = +1

Query: 1   SARGEDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFP-DEQKIVQVACGWRHTLALTENK 177
           +A  E G+L  +G NK GQ+GV D   H     +  P   +++++V+CG   T A T + 
Sbjct: 592 AAIDERGRLLTFGSNKCGQLGVGDYRKHLGINLLGGPLGGKQVIRVSCGDEFTTAATADN 651

Query: 178 NIFSWGRGASGQL 216
           +IF+WG G +G+L
Sbjct: 652 HIFAWGNGGNGRL 664



 Score = 37.0 bits (84), Expect = 0.025
 Identities = 19/65 (29%), Positives = 31/65 (47%)
 Frame = +1

Query: 25  LYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWGRGA 204
           +Y WG  ++G++G++   D  SP +V       IV V CG   +  LT    + + G   
Sbjct: 483 VYSWGCGEYGRLGLDSEDDVYSPQKVEVQRGLCIVNVCCGSDGSFLLTLTGKVLACGLNE 542

Query: 205 SGQLG 219
             +LG
Sbjct: 543 HNKLG 547



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 20/71 (28%), Positives = 33/71 (46%), Gaps = 5/71 (7%)
 Frame = +1

Query: 22  KLYGW-----GWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIF 186
           +LY W     G    GQ+G  D   +  P  V     + + +V+CG   T+ +T+   ++
Sbjct: 371 ELYTWVNMQGGSKLHGQLGHGDRASYRQPKHVEKLQGKSVQKVSCGSDFTVCITDEGQLY 430

Query: 187 SWGRGASGQLG 219
           S+G    G LG
Sbjct: 431 SFGSDYYGCLG 441



 Score = 33.1 bits (74), Expect = 0.36
 Identities = 17/51 (33%), Positives = 24/51 (47%), Gaps = 5/51 (9%)
 Frame = +1

Query: 130 QVACGWRHTLALTENKNIFSW-----GRGASGQLGHGEIIDRNTPKMIDAL 267
           QV  G  H   +T  K +++W     G    GQLGHG+      PK ++ L
Sbjct: 355 QVCAGDAHFAVVTVEKELYTWVNMQGGSKLHGQLGHGDRASYRQPKHVEKL 405



 Score = 28.9 bits (63), Expect = 6.8
 Identities = 21/83 (25%), Positives = 37/83 (44%), Gaps = 13/83 (15%)
 Frame = +1

Query: 19  GKLYGWGWNKFGQVGVEDN----VDHCSPVEVNFPDE---------QKIVQVACGWRHTL 159
           GK+   G N+  ++G+       ++H +  EV +             KI  ++ G  HT 
Sbjct: 533 GKVLACGLNEHNKLGLNQYTAGIINHEAFQEVPYTTSLTLAKQLSFYKIRSISPGRTHTA 592

Query: 160 ALTENKNIFSWGRGASGQLGHGE 228
           A+ E   + ++G    GQLG G+
Sbjct: 593 AIDERGRLLTFGSNKCGQLGVGD 615

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>RPGR_HUMAN (Q92834) X-linked retinitis pigmentosa GTPase regulator|
          Length = 1020

 Score = 55.5 bits (132), Expect = 7e-08
 Identities = 29/77 (37%), Positives = 41/77 (53%)
 Frame = +1

Query: 16  DGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWG 195
           + KLY +G N +GQ+G+        P  V     +K+   ACG  HTL  TE  N+++ G
Sbjct: 53  NNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYATG 112

Query: 196 RGASGQLGHGEIIDRNT 246
               GQLG G+  +RNT
Sbjct: 113 GNNEGQLGLGDTEERNT 129



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 33/85 (38%), Positives = 56/85 (65%), Gaps = 3/85 (3%)
 Frame = +1

Query: 16  DGKLYGWGWNKFGQVGVEDNV--DHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFS 189
           DG+LY +G  + G++G+ + +  +H +P  V+   E K++QVACG  HT+ LTEN  +++
Sbjct: 208 DGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPE-KVIQVACGGEHTVVLTENA-VYT 265

Query: 190 WGRGASGQLGHGE-IIDRNTPKMID 261
           +G G  GQLG G  + + + PK+I+
Sbjct: 266 FGLGQFGQLGLGTFLFETSEPKVIE 290



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 26/83 (31%), Positives = 44/83 (53%), Gaps = 1/83 (1%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNF-PDEQKIVQVACGWRHTLALTENKNIFS 189
           E G +Y  G N  GQ+G+ D  +  +   ++F   E KI Q++ G   + ALTE+  +F 
Sbjct: 104 EGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTSAALTEDGRLFM 163

Query: 190 WGRGASGQLGHGEIIDRNTPKMI 258
           WG  + GQ+G   + +   P+ +
Sbjct: 164 WGDNSEGQIGLKNVSNVCVPQQV 186



 Score = 38.5 bits (88), Expect = 0.009
 Identities = 21/71 (29%), Positives = 39/71 (54%), Gaps = 1/71 (1%)
 Frame = +1

Query: 16  DGKLYGWGWNKFGQVGVEDNVDHCS-PVEVNFPDEQKIVQVACGWRHTLALTENKNIFSW 192
           +  +Y +G  +FGQ+G+   +   S P  +    +Q I  ++CG  HT  +T+   ++++
Sbjct: 260 ENAVYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISCGENHTALITDIGLMYTF 319

Query: 193 GRGASGQLGHG 225
           G G  G+LG G
Sbjct: 320 GDGRHGKLGLG 330



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 15/47 (31%), Positives = 24/47 (51%)
 Frame = +1

Query: 127 VQVACGWRHTLALTENKNIFSWGRGASGQLGHGEIIDRNTPKMIDAL 267
           V ++CG  H+  +T N  ++ +G    GQLG G     + P  + AL
Sbjct: 38  VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKAL 84

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>RPGR_MOUSE (Q9R0X5) X-linked retinitis pigmentosa GTPase regulator (mRpgr)|
          Length = 1001

 Score = 55.5 bits (132), Expect = 7e-08
 Identities = 41/141 (29%), Positives = 62/141 (43%), Gaps = 52/141 (36%)
 Frame = +1

Query: 1   SARGEDGKLYGWGWNKFGQVGVEDNVDHCSPVEV-------------------------- 102
           +A  EDGKL+ WG N  GQ+G+ED  + C P EV                          
Sbjct: 153 AALTEDGKLFMWGDNSEGQIGLEDKSNVCIPHEVTVGKPISWISCGYYHSAFVTMDGELY 212

Query: 103 ----------NFPDE---------------QKIVQVACGWRHTLALTENKNIFSWGRGAS 207
                       P+E               ++++QVACG  HT+ LTE K ++++G G  
Sbjct: 213 TFGEPENGKLGLPNELLMNHRSPQRVLGIPERVIQVACGGGHTVVLTE-KVVYAFGLGQF 271

Query: 208 GQLGHGE-IIDRNTPKMIDAL 267
           GQLG G  + + + PK+I+ +
Sbjct: 272 GQLGLGTFLFETSEPKIIERI 292



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 26/77 (33%), Positives = 40/77 (51%)
 Frame = +1

Query: 16  DGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWG 195
           + KLY +G N +GQ+G+        P  +     +K+   ACG  HTL  T+   +++ G
Sbjct: 53  NNKLYMFGSNNWGQLGLGSKAAIIKPTCIKALKPEKVKLAACGRNHTLVSTDTGGVYAAG 112

Query: 196 RGASGQLGHGEIIDRNT 246
               GQLG G+  DR+T
Sbjct: 113 GNNEGQLGLGDTDDRDT 129



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 23/68 (33%), Positives = 39/68 (57%), Gaps = 1/68 (1%)
 Frame = +1

Query: 25  LYGWGWNKFGQVGVEDNVDHCS-PVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWGRG 201
           +Y +G  +FGQ+G+   +   S P  +    +QKI  ++CG  HT  +TE   ++++G G
Sbjct: 263 VYAFGLGQFGQLGLGTFLFETSEPKIIERIKDQKICHISCGENHTALMTELGLLYTFGDG 322

Query: 202 ASGQLGHG 225
             G+LG G
Sbjct: 323 RHGKLGLG 330



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 24/70 (34%), Positives = 37/70 (52%), Gaps = 1/70 (1%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHCSPVE-VNFPDEQKIVQVACGWRHTLALTENKNIFS 189
           + G +Y  G N  GQ+G+ D  D  +  + V F     I Q++ G   + ALTE+  +F 
Sbjct: 104 DTGGVYAAGGNNEGQLGLGDTDDRDTFHQIVFFTPADTIKQLSAGANTSAALTEDGKLFM 163

Query: 190 WGRGASGQLG 219
           WG  + GQ+G
Sbjct: 164 WGDNSEGQIG 173



 Score = 30.4 bits (67), Expect = 2.3
 Identities = 22/73 (30%), Positives = 34/73 (46%)
 Frame = +1

Query: 49  FGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWGRGASGQLGHGE 228
           FG+    +N+    P +  F ++  I  ++CG  HT  +T N  ++ +G    GQLG G 
Sbjct: 17  FGKTKFAENI----PSKFWFKNDIPIC-LSCGDEHTAIVTGNNKLYMFGSNNWGQLGLGS 71

Query: 229 IIDRNTPKMIDAL 267
                 P  I AL
Sbjct: 72  KAAIIKPTCIKAL 84

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>ALS2_PANTR (Q5BIW4) Alsin (Amyotrophic lateral sclerosis protein 2 homolog)|
          Length = 1657

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 24/69 (34%), Positives = 39/69 (56%)
 Frame = +1

Query: 22  KLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWGRG 201
           +++ WG  K GQ+G  D +    P+ V   D ++++ +  G  H+LALT    ++SWG  
Sbjct: 527 EVWTWGKGKEGQLGHGDVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSN 586

Query: 202 ASGQLGHGE 228
             GQLGH +
Sbjct: 587 TFGQLGHSD 595



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 28/76 (36%), Positives = 41/76 (53%), Gaps = 7/76 (9%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQ-------KIVQVACGWRHTLALTE 171
           ++G  Y WG N  GQ  V +      P  V+  D +       +I+Q+ACG  HTLAL+ 
Sbjct: 108 DNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAVRILQLACGEEHTLALSI 167

Query: 172 NKNIFSWGRGASGQLG 219
           ++ I++WG G   QLG
Sbjct: 168 SREIWAWGTGC--QLG 181



 Score = 37.4 bits (85), Expect = 0.019
 Identities = 16/41 (39%), Positives = 25/41 (60%)
 Frame = +1

Query: 181 IFSWGRGASGQLGHGEIIDRNTPKMIDALSLDGSACKQLES 303
           +++WG+G  GQLGHG+++ R  P  +    LDG     LE+
Sbjct: 528 VWTWGKGKEGQLGHGDVLPRLQPLCVKC--LDGKEVIHLEA 566



 Score = 37.0 bits (84), Expect = 0.025
 Identities = 23/67 (34%), Positives = 36/67 (53%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSW 192
           EDG++Y +G   +    VE  +   SP+  N    Q +V VA G  H+ A+T+N   + W
Sbjct: 58  EDGEVYSFGTLPWRSGPVE--ICPSSPILENALVGQYVVTVATGSFHSGAVTDNGVAYMW 115

Query: 193 GRGASGQ 213
           G  ++GQ
Sbjct: 116 GENSAGQ 122

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>ALS2_HUMAN (Q96Q42) Alsin (Amyotrophic lateral sclerosis protein 2)|
          Length = 1657

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 24/69 (34%), Positives = 39/69 (56%)
 Frame = +1

Query: 22  KLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWGRG 201
           +++ WG  K GQ+G  D +    P+ V   D ++++ +  G  H+LALT    ++SWG  
Sbjct: 527 EVWTWGKGKEGQLGHGDVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSN 586

Query: 202 ASGQLGHGE 228
             GQLGH +
Sbjct: 587 TFGQLGHSD 595



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 28/76 (36%), Positives = 41/76 (53%), Gaps = 7/76 (9%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQ-------KIVQVACGWRHTLALTE 171
           ++G  Y WG N  GQ  V +      P  V+  D +       +I+Q+ACG  HTLAL+ 
Sbjct: 108 DNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAVRILQLACGEEHTLALSI 167

Query: 172 NKNIFSWGRGASGQLG 219
           ++ I++WG G   QLG
Sbjct: 168 SREIWAWGTGC--QLG 181



 Score = 37.4 bits (85), Expect = 0.019
 Identities = 16/41 (39%), Positives = 25/41 (60%)
 Frame = +1

Query: 181 IFSWGRGASGQLGHGEIIDRNTPKMIDALSLDGSACKQLES 303
           +++WG+G  GQLGHG+++ R  P  +    LDG     LE+
Sbjct: 528 VWTWGKGKEGQLGHGDVLPRLQPLCVKC--LDGKEVIHLEA 566



 Score = 36.6 bits (83), Expect = 0.033
 Identities = 22/67 (32%), Positives = 36/67 (53%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSW 192
           EDG++Y +G   +    VE  +   SP+  N    Q ++ VA G  H+ A+T+N   + W
Sbjct: 58  EDGEVYSFGTLPWRSGPVE--ICPSSPILENALVGQYVITVATGSFHSGAVTDNGVAYMW 115

Query: 193 GRGASGQ 213
           G  ++GQ
Sbjct: 116 GENSAGQ 122

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>GNEFR_MOUSE (Q80YD6) Guanine nucleotide exchange factor-related protein|
           (Deafness locus associated putative guanine nucleotide
           exchange factor) (DelGEF)
          Length = 464

 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 26/70 (37%), Positives = 39/70 (55%), Gaps = 1/70 (1%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDN-VDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFS 189
           + G+LY WG NK GQ+      +     +E ++  ++K+  V  GW H +A TE   +F+
Sbjct: 229 DTGELYVWGRNKHGQLASRAVFLPLPQRIEAHYFQDEKVTAVWSGWTHLVAKTETGKVFT 288

Query: 190 WGRGASGQLG 219
           WGR   GQLG
Sbjct: 289 WGRADYGQLG 298



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 33/101 (32%), Positives = 46/101 (45%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSW 192
           E G++   G N FGQ+GV      C   +      +K+V VA G RH LA T   ++F W
Sbjct: 118 EKGQVLSCGSNAFGQLGVPHGPRKCVVPQAIECLREKVVCVAAGLRHALATTATGSVFQW 177

Query: 193 GRGASGQLGHGEIIDRNTPKMIDALSLDGSACKQLESSNVV 315
           G G +   G      +N P  + A   + S    LE+S  V
Sbjct: 178 GTGLASS-GRRLCPGQNLPLFLTA--KEPSRVTGLENSTAV 215



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 30/78 (38%), Positives = 38/78 (48%), Gaps = 7/78 (8%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDH-----CSPVEVNFPDEQKIVQVACGWRHTLALTENK 177
           + G L+  G NK GQ+G+    +      C P+         I QVACGW  T+ LTE  
Sbjct: 66  DGGDLFVCGLNKDGQLGLGHTEEVLRFTICKPLR-----GCPIRQVACGWDFTIMLTEKG 120

Query: 178 NIFSWGRGASGQLG--HG 225
            + S G  A GQLG  HG
Sbjct: 121 QVLSCGSNAFGQLGVPHG 138



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 19/52 (36%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
 Frame = +1

Query: 22  KLYGWGWNKFGQVG--VEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTE 171
           K   WGWN+ G  G   E NV   +PV+   P   +++ V CG  H+LA+ +
Sbjct: 352 KCCSWGWNEHGMCGDGTESNVWTPTPVQALPPSPSRLLLVGCGAGHSLAVCQ 403



 Score = 38.5 bits (88), Expect = 0.009
 Identities = 22/68 (32%), Positives = 34/68 (50%), Gaps = 1/68 (1%)
 Frame = +1

Query: 25  LYGWGWNKFGQVGVEDNVDHCSPVEV-NFPDEQKIVQVACGWRHTLALTENKNIFSWGRG 201
           L+ WG N +GQ+G+    D   P ++ +F     I  V  G  H+  +T+  ++F  G  
Sbjct: 17  LFAWGANSYGQLGLGHKEDVFLPQQLSDFCQAGCIKSVTGGGGHSAVVTDGGDLFVCGLN 76

Query: 202 ASGQLGHG 225
             GQLG G
Sbjct: 77  KDGQLGLG 84



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 30/109 (27%), Positives = 42/109 (38%), Gaps = 21/109 (19%)
 Frame = +1

Query: 4   ARGEDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQK-------------------- 123
           A+ E GK++ WG   +GQ+G         P E   P EQ                     
Sbjct: 279 AKTETGKVFTWGRADYGQLG-----RRLEPPEAQKPVEQDSSLAFQGPQNSVPSPLHCLT 333

Query: 124 -IVQVACGWRHTLALTENKNIFSWGRGASGQLGHGEIIDRNTPKMIDAL 267
              +++CG  H LA+  +K   SWG    G  G G   +  TP  + AL
Sbjct: 334 GATEISCGSEHNLAVIRDK-CCSWGWNEHGMCGDGTESNVWTPTPVQAL 381

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>RPGRH_CAEEL (Q5DX34) X-linked retinitis pigmentosa GTPase regulator homolog|
          Length = 1392

 Score = 52.0 bits (123), Expect = 8e-07
 Identities = 31/93 (33%), Positives = 51/93 (54%), Gaps = 2/93 (2%)
 Frame = +1

Query: 19   GKLYGWGWNKFGQVGVEDN--VDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSW 192
            G+L  WG N+FGQ GV  +  + +   V+ ++P  +KI   ACG  H+  +  + +++++
Sbjct: 795  GQLSAWGGNRFGQCGVGHSFRIANLHQVDGDWPAIEKI---ACGQFHSAFICSDGSLWTF 851

Query: 193  GRGASGQLGHGEIIDRNTPKMIDALSLDGSACK 291
            G G  GQLGHG    RN    +    ++G  CK
Sbjct: 852  GWGVWGQLGHG---GRNNSNQLVPTRVNGLICK 881



 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 24/68 (35%), Positives = 38/68 (55%)
 Frame = +1

Query: 16   DGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWG 195
            +G LY WG     Q+G  +  +   P +V  P+  K V V+ G  HT+A T++ ++F+WG
Sbjct: 1040 EGTLYTWGKGLDYQLGHGNKNERMEPHQVFEPNGAKWVNVSLGNNHTIASTDDGSVFAWG 1099

Query: 196  RGASGQLG 219
            +   GQ G
Sbjct: 1100 KNDFGQCG 1107



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 26/70 (37%), Positives = 39/70 (55%), Gaps = 2/70 (2%)
 Frame = +1

Query: 16   DGKLYGWGWNKFGQVGV--EDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFS 189
            DG L+ +GW  +GQ+G    +N +   P  VN     K+ Q+ACG  HT+ LT+   +  
Sbjct: 845  DGSLWTFGWGVWGQLGHGGRNNSNQLVPTRVNGLI-CKVTQIACGRAHTVVLTDTGRVLV 903

Query: 190  WGRGASGQLG 219
             G G+ GQ+G
Sbjct: 904  CGSGSYGQMG 913



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 18/45 (40%), Positives = 26/45 (57%)
 Frame = +1

Query: 124  IVQVACGWRHTLALTENKNIFSWGRGASGQLGHGEIIDRNTPKMI 258
            IV VACG  H+  +T    +++WG+G   QLGHG   +R  P  +
Sbjct: 1024 IVSVACGLSHSALITSEGTLYTWGKGLDYQLGHGNKNERMEPHQV 1068



 Score = 35.8 bits (81), Expect = 0.056
 Identities = 15/62 (24%), Positives = 32/62 (51%)
 Frame = +1

Query: 13   EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSW 192
            + G++   G   +GQ+GV+D++              ++  +A  + H++ +TE+  +F W
Sbjct: 897  DTGRVLVCGSGSYGQMGVDDDIKKVFAFTPLPLGPLRVRDIATHYYHSICITEDNRVFEW 956

Query: 193  GR 198
            GR
Sbjct: 957  GR 958



 Score = 30.8 bits (68), Expect = 1.8
 Identities = 17/60 (28%), Positives = 27/60 (45%), Gaps = 2/60 (3%)
 Frame = +1

Query: 133 VACGWRHTLALTENKNIFSWGRGASGQLGHGEIIDRNTPKMIDA--LSLDGSACKQLESS 306
           +ACG  H L L+ +  + +WG    GQ G G          +D    +++  AC Q  S+
Sbjct: 781 IACGAEHILVLSSSGQLSAWGGNRFGQCGVGHSFRIANLHQVDGDWPAIEKIACGQFHSA 840



 Score = 29.3 bits (64), Expect = 5.2
 Identities = 11/21 (52%), Positives = 14/21 (66%)
 Frame = +1

Query: 4    ARGEDGKLYGWGWNKFGQVGV 66
            A  +DG ++ WG N FGQ GV
Sbjct: 1088 ASTDDGSVFAWGKNDFGQCGV 1108

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>RPGR_CANFA (Q9N1T2) X-linked retinitis pigmentosa GTPase regulator|
          Length = 1003

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 34/86 (39%), Positives = 53/86 (61%), Gaps = 4/86 (4%)
 Frame = +1

Query: 16  DGKLYGWGWNKFGQVGVEDN--VDHCSPVEV-NFPDEQKIVQVACGWRHTLALTENKNIF 186
           +G+LY +G  + G++G+ +   V+H  P  V   P   K+VQVACG  HT+ LTE K ++
Sbjct: 208 EGQLYTFGEPECGKLGLPNQLLVNHRMPQPVPGIPG--KVVQVACGGGHTVVLTE-KAVY 264

Query: 187 SWGRGASGQLGHGE-IIDRNTPKMID 261
           ++G G  GQLG G  + + + PK I+
Sbjct: 265 TFGLGQFGQLGLGTFLFETSVPKAIE 290



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 28/81 (34%), Positives = 42/81 (51%)
 Frame = +1

Query: 16  DGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWG 195
           + KLY +G N +GQ+G+        P  V     +K+   ACG  HTL  TE   +++ G
Sbjct: 53  NNKLYMFGSNNWGQLGLGSKSTVSKPTCVKALKPEKVKFAACGRNHTLVSTEGGKVYAAG 112

Query: 196 RGASGQLGHGEIIDRNTPKMI 258
               GQLG G+  +R+T  +I
Sbjct: 113 GNNEGQLGLGDTEERSTFHLI 133



 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 24/73 (32%), Positives = 43/73 (58%)
 Frame = +1

Query: 1   SARGEDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKN 180
           +A  EDG+L+ WG N  GQ+G+E+  + C P +V     + I  ++CG+ H+  +T    
Sbjct: 153 AALTEDGELFMWGDNSEGQIGLENVTNVCVPQQVTV--GKPISWISCGYYHSAFVTTEGQ 210

Query: 181 IFSWGRGASGQLG 219
           ++++G    G+LG
Sbjct: 211 LYTFGEPECGKLG 223



 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 26/83 (31%), Positives = 46/83 (55%), Gaps = 1/83 (1%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNF-PDEQKIVQVACGWRHTLALTENKNIFS 189
           E GK+Y  G N  GQ+G+ D  +  +   ++F   ++KI Q++ G   + ALTE+  +F 
Sbjct: 104 EGGKVYAAGGNNEGQLGLGDTEERSTFHLISFFTSQRKIKQLSAGSNTSAALTEDGELFM 163

Query: 190 WGRGASGQLGHGEIIDRNTPKMI 258
           WG  + GQ+G   + +   P+ +
Sbjct: 164 WGDNSEGQIGLENVTNVCVPQQV 186



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 26/82 (31%), Positives = 46/82 (56%), Gaps = 1/82 (1%)
 Frame = +1

Query: 25  LYGWGWNKFGQVGVEDNVDHCS-PVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWGRG 201
           +Y +G  +FGQ+G+   +   S P  +    +QKI  +ACG  HT  +T+   ++++G G
Sbjct: 263 VYTFGLGQFGQLGLGTFLFETSVPKAIEHIKDQKISFIACGENHTALITDMGLMYTFGDG 322

Query: 202 ASGQLGHGEIIDRNTPKMIDAL 267
             G+LG G  ++ +T + I  L
Sbjct: 323 RHGKLGLG--LENSTNQFIPTL 342



 Score = 31.6 bits (70), Expect = 1.0
 Identities = 15/45 (33%), Positives = 23/45 (51%)
 Frame = +1

Query: 133 VACGWRHTLALTENKNIFSWGRGASGQLGHGEIIDRNTPKMIDAL 267
           ++CG  HT  +T N  ++ +G    GQLG G     + P  + AL
Sbjct: 40  LSCGDEHTAVVTGNNKLYMFGSNNWGQLGLGSKSTVSKPTCVKAL 84

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>GNEFR_HUMAN (Q9UGK8) Guanine nucleotide exchange factor-related protein|
           (Deafness locus associated putative guanine nucleotide
           exchange factor) (DelGEF)
          Length = 458

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 25/68 (36%), Positives = 37/68 (54%), Gaps = 1/68 (1%)
 Frame = +1

Query: 19  GKLYGWGWNKFGQVGVEDN-VDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWG 195
           G++Y WG NK GQ+  E   +     +E +    +K+  +  GW H +A TE   +F+WG
Sbjct: 231 GEVYVWGSNKHGQLANEAAFLPVPQKIEAHCFQNEKVTAIWSGWTHLVAQTETGKMFTWG 290

Query: 196 RGASGQLG 219
           R   GQLG
Sbjct: 291 RADYGQLG 298



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 30/75 (40%), Positives = 43/75 (57%), Gaps = 4/75 (5%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGV--EDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIF 186
           + G L+  G NK GQ+G+   +++ + +P +  F     I QVACGW  T+ LTEN  + 
Sbjct: 66  DGGDLFVCGLNKDGQLGLGHTEDIPYFTPCKSLFGCP--IQQVACGWDFTIMLTENGQVL 123

Query: 187 SWGRGASGQLG--HG 225
           S G  + GQLG  HG
Sbjct: 124 SCGSNSFGQLGVPHG 138



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 22/63 (34%), Positives = 34/63 (53%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSW 192
           E+G++   G N FGQ+GV      C   +     ++K+V +A G RH +A T +  +F W
Sbjct: 118 ENGQVLSCGSNSFGQLGVPHGPRRCVVPQAIELHKEKVVCIAAGLRHAVAATASGIVFQW 177

Query: 193 GRG 201
           G G
Sbjct: 178 GTG 180



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 27/92 (29%), Positives = 44/92 (47%), Gaps = 1/92 (1%)
 Frame = +1

Query: 25  LYGWGWNKFGQVGVEDNVDHCSPVEVN-FPDEQKIVQVACGWRHTLALTENKNIFSWGRG 201
           L+ WG N +GQ+G+    D   P ++N F   + + ++  G  H+  +T+  ++F  G  
Sbjct: 17  LFAWGANSYGQLGLGHKEDVLLPQQLNDFCKPRSVRRITGGGGHSAVVTDGGDLFVCGLN 76

Query: 202 ASGQLGHGEIIDRNTPKMIDALSLDGSACKQL 297
             GQLG G   D   P      SL G   +Q+
Sbjct: 77  KDGQLGLGHTED--IPYFTPCKSLFGCPIQQV 106



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 29/104 (27%), Positives = 44/104 (42%), Gaps = 16/104 (15%)
 Frame = +1

Query: 4   ARGEDGKLYGWGWNKFGQVG------------VEDNVDHCSPVEVNFPDEQKIV----QV 135
           A+ E GK++ WG   +GQ+G             +D+   CS    + P     +    +V
Sbjct: 279 AQTETGKMFTWGRADYGQLGRKLETYEGWKLEKQDSFLPCSRPPNSMPSSPHCLTGATEV 338

Query: 136 ACGWRHTLALTENKNIFSWGRGASGQLGHGEIIDRNTPKMIDAL 267
           +CG  H LA+      +SWG    G  G G   +   PK + AL
Sbjct: 339 SCGSEHNLAIIGGV-CYSWGWNEHGMCGDGTEANVWAPKPVQAL 381



 Score = 33.9 bits (76), Expect = 0.21
 Identities = 17/51 (33%), Positives = 23/51 (45%)
 Frame = +1

Query: 19  GKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTE 171
           G  Y WGWN+ G  G     +  +P  V        + V CG  H+LAL +
Sbjct: 351 GVCYSWGWNEHGMCGDGTEANVWAPKPVQALLSSSGLLVGCGAGHSLALCQ 401



 Score = 28.5 bits (62), Expect = 8.9
 Identities = 17/58 (29%), Positives = 27/58 (46%)
 Frame = +1

Query: 91  PVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWGRGASGQLGHGEIIDRNTPKMIDA 264
           P  V   +  K + V  G  H+ +LT+   ++ WG    GQL + E      P+ I+A
Sbjct: 203 PSRVTGLENSKAMCVLAGSDHSASLTDAGEVYVWGSNKHGQLAN-EAAFLPVPQKIEA 259

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>NEK8_HUMAN (Q86SG6) Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never|
           in mitosis A-related kinase 8) (NimA-related protein
           kinase 8) (NIMA-related kinase 12a)
          Length = 692

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 24/67 (35%), Positives = 37/67 (55%)
 Frame = +1

Query: 19  GKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWGR 198
           G  Y +G N+ GQ+G        +P +V   +  K+  VACG   T+A+     ++SWG+
Sbjct: 580 GDCYTFGSNQHGQLGTNTRRGSRAPCKVQGLEGIKMAMVACGDAFTVAIGAESEVYSWGK 639

Query: 199 GASGQLG 219
           GA G+LG
Sbjct: 640 GARGRLG 646



 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 28/80 (35%), Positives = 41/80 (51%)
 Frame = +1

Query: 19  GKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWGR 198
           G +  +G    G +G     D   P  V      ++VQVACG  H LAL+  + +F+WGR
Sbjct: 410 GIIMTFGSGSNGCLGHGSLTDISQPTIVEALLGYEMVQVACGASHVLALSTERELFAWGR 469

Query: 199 GASGQLGHGEIIDRNTPKMI 258
           G SG+LG G     + P+ +
Sbjct: 470 GDSGRLGLGTRESHSCPQQV 489



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 20/48 (41%), Positives = 30/48 (62%)
 Frame = +1

Query: 124 IVQVACGWRHTLALTENKNIFSWGRGASGQLGHGEIIDRNTPKMIDAL 267
           I  VACG   T  LT+   I ++G G++G LGHG + D + P +++AL
Sbjct: 393 IKHVACGDFFTACLTDRGIIMTFGSGSNGCLGHGSLTDISQPTIVEAL 440



 Score = 36.2 bits (82), Expect = 0.043
 Identities = 19/72 (26%), Positives = 32/72 (44%)
 Frame = +1

Query: 4   ARGEDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNI 183
           A   + +L+ WG    G++G+     H  P +V  P  Q+  +V CG   ++ LT     
Sbjct: 457 ALSTERELFAWGRGDSGRLGLGTRESHSCPQQVPMPPGQEAQRVVCGIDSSMILTVPGQA 516

Query: 184 FSWGRGASGQLG 219
            + G     +LG
Sbjct: 517 LACGSNRFNKLG 528

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>NEK8_MOUSE (Q91ZR4) Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never|
           in mitosis A-related kinase 8) (NimA-related protein
           kinase 8)
          Length = 698

 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 28/80 (35%), Positives = 41/80 (51%)
 Frame = +1

Query: 19  GKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWGR 198
           G +  +G    G +G  +  D   P  V      ++VQVACG  H LAL+ +  +F+WGR
Sbjct: 416 GIIMTFGSGSNGCLGHGNLTDISQPTIVEALLGYEMVQVACGASHVLALSTDGELFAWGR 475

Query: 199 GASGQLGHGEIIDRNTPKMI 258
           G  G+LG G     N P+ +
Sbjct: 476 GDGGRLGLGTRESHNCPQQV 495



 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 28/93 (30%), Positives = 45/93 (48%), Gaps = 9/93 (9%)
 Frame = +1

Query: 19  GKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWGR 198
           G  Y +G N+ GQ+G        +P  V   +  K+V VACG   T+A+     ++SWG+
Sbjct: 586 GDCYTFGSNQHGQLGTSSRRVSRAPCRVQGLEGIKMVMVACGDAFTVAVGAEGEVYSWGK 645

Query: 199 GASGQLGHGE---------IIDRNTPKMIDALS 270
           G  G+LG  +          +D   P M+ ++S
Sbjct: 646 GTRGRLGRRDEDAGLPRPVQLDETHPYMVTSVS 678



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 20/48 (41%), Positives = 30/48 (62%)
 Frame = +1

Query: 124 IVQVACGWRHTLALTENKNIFSWGRGASGQLGHGEIIDRNTPKMIDAL 267
           I  VACG   T  LT+   I ++G G++G LGHG + D + P +++AL
Sbjct: 399 IKHVACGDLFTACLTDRGIIMTFGSGSNGCLGHGNLTDISQPTIVEAL 446



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 25/91 (27%), Positives = 39/91 (42%)
 Frame = +1

Query: 4   ARGEDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNI 183
           A   DG+L+ WG    G++G+     H  P +V     Q+  +V CG   ++ LT    +
Sbjct: 463 ALSTDGELFAWGRGDGGRLGLGTRESHNCPQQVPVAPGQEAQRVVCGIDSSMILTSPGRV 522

Query: 184 FSWGRGASGQLGHGEIIDRNTPKMIDALSLD 276
            + G     +LG            +D LSLD
Sbjct: 523 LACGSNRFNKLG------------LDHLSLD 541

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>RCC1_SCHPO (P28745) Protein pim1 (Poly(A)+ RNA transport protein 2)|
          Length = 539

 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 23/84 (27%), Positives = 40/84 (47%), Gaps = 12/84 (14%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNV------------DHCSPVEVNFPDEQKIVQVACGWRHT 156
           EDG++  WG +   Q+G+ DN             ++        P    ++QV CG  H 
Sbjct: 353 EDGRVLAWGRDDRHQLGIPDNALPETVVKDEKGNNYYLSTPTIIPGLTNVIQVVCGTHHN 412

Query: 157 LALTENKNIFSWGRGASGQLGHGE 228
           LA+T +  ++SWG   + ++G G+
Sbjct: 413 LAVTSDGKVYSWGSAENYEVGQGD 436



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 35/144 (24%), Positives = 59/144 (40%), Gaps = 8/144 (5%)
 Frame = +1

Query: 19  GKLYGWGWNKFGQVGVEDNVDH-----CSPVEVNFPDEQKIVQVACGWRHTLALTENKNI 183
           G++Y WG N   Q G+E   +        P  V+  +   +  +  G  HTLAL E+  +
Sbjct: 298 GRVYAWGLNITRQCGIEVEDEEEGAVITKPTLVDALEGYNVKSITGGEHHTLALLEDGRV 357

Query: 184 FSWGRGASGQLGHGEIIDRNTPKMIDALSLDGSACKQLESSNVVP---MTVKVWVSPSER 354
            +WGR    QLG   I D   P+ +  +  +      L +  ++P     ++V       
Sbjct: 358 LAWGRDDRHQLG---IPDNALPETV--VKDEKGNNYYLSTPTIIPGLTNVIQVVCGTHHN 412

Query: 355 FALVPDENVCKSGNGTDKHAPEGD 426
            A+  D  V   G+  +    +GD
Sbjct: 413 LAVTSDGKVYSWGSAENYEVGQGD 436



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 27/104 (25%), Positives = 48/104 (46%), Gaps = 3/104 (2%)
 Frame = +1

Query: 13  EDGKLYGWGWNKF--GQVGVEDNVDHCS-PVEVNFPDEQKIVQVACGWRHTLALTENKNI 183
           ++G  + WG  +   G +G  D+    + P ++  P+   I Q+A G  H +ALT    +
Sbjct: 191 DNGCCFTWGTFRCSDGVLGYSDSQKRTAEPTQMRLPE---ICQLATGTDHIIALTTTGKV 247

Query: 184 FSWGRGASGQLGHGEIIDRNTPKMIDALSLDGSACKQLESSNVV 315
           ++WG G   QLG          +M++   L G   + L   N++
Sbjct: 248 YTWGNGQQFQLGR---------RMLERRRLQGLTPQPLALKNII 282



 Score = 32.7 bits (73), Expect = 0.47
 Identities = 24/92 (26%), Positives = 43/92 (46%), Gaps = 16/92 (17%)
 Frame = +1

Query: 1   SARGEDGKLYGWGWNKFGQVG-------------VEDNVDHCSPVEVNFP-DEQKIVQVA 138
           +A   DG++Y WG N    +G             V++++   +P +V       ++ +V 
Sbjct: 121 AALSHDGRVYTWGVNDDYALGRLTKDQKDENGDKVDNDLLEGTPSKVEGALSHLRVTKVI 180

Query: 139 CGWRHTLALTENKNIFSWG--RGASGQLGHGE 228
           C    T A+T+N   F+WG  R + G LG+ +
Sbjct: 181 CSDNLTAAITDNGCCFTWGTFRCSDGVLGYSD 212

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>RPM1_CAEEL (Q17551) Ubiquitin ligase protein rpm-1 (EC 6.3.2.-)|
           (Pam/highwire/rpm-1 protein) (Regulator of presynaptic
           morphology protein 1) (Synapse defective protein 3)
          Length = 3766

 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 24/67 (35%), Positives = 39/67 (58%)
 Frame = +1

Query: 16  DGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWG 195
           D +++ +G N  GQ+GV D +   +P +V  P +  IVQVA G  HT+    + ++F++G
Sbjct: 785 DRRVFTFGSNCHGQLGVGDTLSKNTPQQVILPSDTVIVQVAAGSNHTILRANDGSVFTFG 844

Query: 196 RGASGQL 216
               GQL
Sbjct: 845 AFGKGQL 851



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 18/50 (36%), Positives = 32/50 (64%)
 Frame = +1

Query: 109 PDEQKIVQVACGWRHTLALTENKNIFSWGRGASGQLGHGEIIDRNTPKMI 258
           P + K+  V+CG  HT+ L  ++ +F++G    GQLG G+ + +NTP+ +
Sbjct: 764 PHDVKVSSVSCGNFHTVLLASDRRVFTFGSNCHGQLGVGDTLSKNTPQQV 813

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>RCC1_YEAST (P21827) Regulator of chromosome condensation (PRP20 protein)|
           (Pheromone response pathway component SRM1)
          Length = 482

 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 24/66 (36%), Positives = 38/66 (57%), Gaps = 4/66 (6%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDH----CSPVEVNFPDEQKIVQVACGWRHTLALTENKN 180
           +D KL  WG N+FGQ GV ++V+       P  +  PD   I  +A G  H+L L+++ +
Sbjct: 291 KDNKLVSWGLNQFGQCGVSEDVEDGALVTKPKRLALPDNVVIRSIAAGEHHSLILSQDGD 350

Query: 181 IFSWGR 198
           ++S GR
Sbjct: 351 LYSCGR 356



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 22/51 (43%), Positives = 27/51 (52%)
 Frame = +1

Query: 112 DEQKIVQVACGWRHTLALTENKNIFSWGRGASGQLGHGEIIDRNTPKMIDA 264
           DE KI+  A G  HTLAL E  N++SWG    G LG      +   K +DA
Sbjct: 82  DEAKIISFAVGGMHTLALDEESNVWSWGCNDVGALGRDTSNAKEQLKDMDA 132



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 27/87 (31%), Positives = 46/87 (52%), Gaps = 5/87 (5%)
 Frame = +1

Query: 16  DGKLYGWGWNKFGQVGV----EDNVD-HCSPVEVNFPDEQKIVQVACGWRHTLALTENKN 180
           +G++Y WG  +  + G+    +D +    +P +V    +  IVQ+A G  H L L E   
Sbjct: 183 NGEVYAWGTFRCNE-GILGFYQDKIKIQKTPWKVPTFSKYNIVQLAPGKDHILFLDEEGM 241

Query: 181 IFSWGRGASGQLGHGEIIDRNTPKMID 261
           +F+WG G   QLG  ++++R   K +D
Sbjct: 242 VFAWGNGQQNQLGR-KVMERFRLKTLD 267



 Score = 32.3 bits (72), Expect = 0.62
 Identities = 20/79 (25%), Positives = 35/79 (44%), Gaps = 4/79 (5%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVED----NVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKN 180
           E+G ++ WG  +  Q+G +      +    P        + +  +A G  H  ALT++  
Sbjct: 238 EEGMVFAWGNGQQNQLGRKVMERFRLKTLDPRPFGL---RHVKYIASGENHCFALTKDNK 294

Query: 181 IFSWGRGASGQLGHGEIID 237
           + SWG    GQ G  E ++
Sbjct: 295 LVSWGLNQFGQCGVSEDVE 313

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>NEK8_BRARE (Q90XC2) Serine/threonine-protein kinase Nek8 (EC 2.7.11.1)|
           (NimA-related protein kinase 8)
          Length = 697

 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 20/46 (43%), Positives = 30/46 (65%)
 Frame = +1

Query: 121 KIVQVACGWRHTLALTENKNIFSWGRGASGQLGHGEIIDRNTPKMI 258
           ++VQV+CG  H LA+T  + +FSWGRG +G+LG       N P+ +
Sbjct: 451 ELVQVSCGASHVLAVTNEREVFSWGRGDNGRLGLATQDSHNCPQQV 496



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 25/72 (34%), Positives = 38/72 (52%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSW 192
           E G+ + +G N+ GQ+G         P +V+    Q I   ACG   TLA+     +++W
Sbjct: 585 EKGQCFTFGSNQHGQLGCSHRRSSRVPYQVS--GLQGITMAACGDAFTLAIGAEGEVYTW 642

Query: 193 GRGASGQLGHGE 228
           G+GA G+LG  E
Sbjct: 643 GKGARGRLGRKE 654



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 20/48 (41%), Positives = 29/48 (60%)
 Frame = +1

Query: 124 IVQVACGWRHTLALTENKNIFSWGRGASGQLGHGEIIDRNTPKMIDAL 267
           I  V+CG   T  LT+   I ++G G++G LGHG   D   PK+++AL
Sbjct: 400 IKSVSCGDLFTTCLTDRGIIMTFGSGSNGCLGHGNFNDVTQPKIVEAL 447



 Score = 33.9 bits (76), Expect = 0.21
 Identities = 24/91 (26%), Positives = 39/91 (42%), Gaps = 14/91 (15%)
 Frame = +1

Query: 37  GWNKFGQVGV------EDNVDHCSPVEVNF--------PDEQKIVQVACGWRHTLALTEN 174
           G N+F ++G+      E+    C   EV+          + +KIV +  G  H++A+TE 
Sbjct: 527 GNNRFNKLGLDKVSGTEEPSSFCQVEEVHLFQLVQSAPLNTEKIVYIDIGTAHSVAVTEK 586

Query: 175 KNIFSWGRGASGQLGHGEIIDRNTPKMIDAL 267
              F++G    GQLG         P  +  L
Sbjct: 587 GQCFTFGSNQHGQLGCSHRRSSRVPYQVSGL 617



 Score = 33.9 bits (76), Expect = 0.21
 Identities = 16/76 (21%), Positives = 35/76 (46%)
 Frame = +1

Query: 22  KLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWGRG 201
           +++ WG    G++G+     H  P +V+ P + +  +V CG   ++ ++    I + G  
Sbjct: 470 EVFSWGRGDNGRLGLATQDSHNCPQQVSLPADFEAQRVLCGVDCSMIMSTQHQILACGNN 529

Query: 202 ASGQLGHGEIIDRNTP 249
              +LG  ++     P
Sbjct: 530 RFNKLGLDKVSGTEEP 545

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>WBS16_MOUSE (Q9CYF5) Williams-Beuren syndrome chromosome region 16 protein|
           homolog
          Length = 461

 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 29/84 (34%), Positives = 43/84 (51%), Gaps = 12/84 (14%)
 Frame = +1

Query: 22  KLYGWGWNKFGQVGVE----------DNVDHCSPVEVNF--PDEQKIVQVACGWRHTLAL 165
           K++G G NK  Q+G            + V   SPV +    P E K++QV+CG  H+L L
Sbjct: 127 KVWGMGLNKDSQLGFHRSRKDKTRGYEYVLEPSPVPLPLDRPQETKVLQVSCGRAHSLVL 186

Query: 166 TENKNIFSWGRGASGQLGHGEIID 237
           T+ + +FS G  + GQ G   + D
Sbjct: 187 TDREGVFSMGNNSHGQCGRKVVED 210



 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 30/82 (36%), Positives = 41/82 (50%), Gaps = 4/82 (4%)
 Frame = +1

Query: 25  LYGWGWNKFGQVG---VEDNVDHCSPVEVNFPD-EQKIVQVACGWRHTLALTENKNIFSW 192
           ++  G N  GQ G   VED V   S       D + ++VQV CG  H+L LT+   ++S 
Sbjct: 192 VFSMGNNSHGQCGRKVVEDEVYSESHKVHRMQDFDGQVVQVVCGQDHSLFLTDKGEVYSC 251

Query: 193 GRGASGQLGHGEIIDRNTPKMI 258
           G GA GQ G G     +TP  +
Sbjct: 252 GWGADGQTGLGHYNITSTPSKL 273



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 29/91 (31%), Positives = 44/91 (48%), Gaps = 6/91 (6%)
 Frame = +1

Query: 4   ARGEDGKLYGWGWNKFGQVG-----VEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALT 168
           A   DG ++GWG +++ Q+       + NV  C P    F    K+ QVACG      L 
Sbjct: 294 ALSADGGVFGWGNSEYLQLASVTDSTQVNVPRCLP----FSGVGKVKQVACGGTGCAVLN 349

Query: 169 ENKNIFSWGRGASGQLGHG-EIIDRNTPKMI 258
              ++F WG G    LG G ++++   P+MI
Sbjct: 350 AEGHVFVWGYGI---LGKGPKLLETAIPEMI 377



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 24/84 (28%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
 Frame = +1

Query: 16  DGKLYGWGWNKFGQVG--VEDNVDHCSPVEV----NFPDEQKIVQVACGWRHTLALTENK 177
           +G ++ WG+   G+    +E  +    P  +     F  E ++ Q+ CG  H  ALT   
Sbjct: 351 EGHVFVWGYGILGKGPKLLETAIPEMIPPTLFGLTEFNPEVQVSQIRCGLSHFAALTNKG 410

Query: 178 NIFSWGRGASGQLGHGEIIDRNTP 249
            +F WG+   G LG G + D+  P
Sbjct: 411 ELFVWGKNIRGCLGIGRLEDQYFP 434



 Score = 28.9 bits (63), Expect = 6.8
 Identities = 20/69 (28%), Positives = 31/69 (44%), Gaps = 1/69 (1%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFP-DEQKIVQVACGWRHTLALTENKNIFS 189
           + G++Y  GW   GQ G+       +P ++        +VQVA      LAL+ +  +F 
Sbjct: 244 DKGEVYSCGWGADGQTGLGHYNITSTPSKLGGDLAGVTVVQVATYGDCCLALSADGGVFG 303

Query: 190 WGRGASGQL 216
           WG     QL
Sbjct: 304 WGNSEYLQL 312

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>RCC1_MOUSE (Q8VE37) Regulator of chromosome condensation (Chromosome|
           condensation protein 1)
          Length = 421

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 25/71 (35%), Positives = 41/71 (57%), Gaps = 2/71 (2%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSW 192
           + G++Y +G N  G +G + +V+    V      ++K+VQV+ G  HT ALTE+  +F W
Sbjct: 84  QSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEKVVQVSAGDSHTAALTEDGRVFLW 143

Query: 193 G--RGASGQLG 219
           G  R  +G +G
Sbjct: 144 GSFRDNNGVIG 154



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 22/78 (28%), Positives = 41/78 (52%)
 Frame = +1

Query: 16  DGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWG 195
           +GK Y  G  ++G++G+ +  +  S +         +  VACG     A++++  +F+WG
Sbjct: 312 EGKAYSLGRAEYGRLGLGEGAEEKS-IPTLISRLPVVSSVACGASVGYAVSKDGRVFAWG 370

Query: 196 RGASGQLGHGEIIDRNTP 249
            G + QLG G+  D  +P
Sbjct: 371 MGTNYQLGTGQDEDAWSP 388



 Score = 34.7 bits (78), Expect = 0.12
 Identities = 28/99 (28%), Positives = 47/99 (47%), Gaps = 4/99 (4%)
 Frame = +1

Query: 4   ARGEDGKLYGWGWNKFGQVGVEDNVDHCSPVEV-NFPDEQKI-VQVACGWRHTLALTENK 177
           A   +G +YG+G + + Q+G         P  + +F +  K  V  + G  HT+ +    
Sbjct: 254 AISREGHVYGFGLSNYHQLGTPGTGSCFIPQNLTSFKNSTKSWVGFSGGQHHTVCMDSEG 313

Query: 178 NIFSWGRGASGQLGHGE-IIDRNTPKMIDALSLDGS-AC 288
             +S GR   G+LG GE   +++ P +I  L +  S AC
Sbjct: 314 KAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPVVSSVAC 352



 Score = 34.7 bits (78), Expect = 0.12
 Identities = 22/76 (28%), Positives = 38/76 (50%), Gaps = 1/76 (1%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNV-DHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFS 189
           E G +   G    GQ+G+ ++V +   P  V  P  Q +VQ   G  HT+ L+++  ++S
Sbjct: 33  EPGLVLTLGQGDVGQLGLGESVLERKKPALV--PLLQDVVQAEAGGMHTVCLSQSGQVYS 90

Query: 190 WGRGASGQLGHGEIID 237
           +G    G LG    ++
Sbjct: 91  FGCNDEGALGRDTSVE 106



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 17/60 (28%), Positives = 34/60 (56%), Gaps = 2/60 (3%)
 Frame = +1

Query: 4   ARGEDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFP--DEQKIVQVACGWRHTLALTENK 177
           A  +DG+++ WG     Q+G   + D  SPVE+     + + ++ V+ G +HT+ L +++
Sbjct: 359 AVSKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMTGKQLENRVVLTVSSGGQHTVLLVKDQ 418

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>RCC1_MESAU (P23800) Regulator of chromosome condensation (Chromosome|
           condensation protein 1)
          Length = 421

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 25/71 (35%), Positives = 41/71 (57%), Gaps = 2/71 (2%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSW 192
           + G++Y +G N  G +G + +V+    V      ++K+VQV+ G  HT ALTE+  +F W
Sbjct: 84  QSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEKVVQVSAGDSHTAALTEDGRVFLW 143

Query: 193 G--RGASGQLG 219
           G  R  +G +G
Sbjct: 144 GSFRDNNGVIG 154



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 22/78 (28%), Positives = 41/78 (52%)
 Frame = +1

Query: 16  DGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWG 195
           +GK Y  G  ++G++G+ +  +  S +         +  VACG     A++++  +F+WG
Sbjct: 312 EGKAYSLGRAEYGRLGLGEGAEEKS-IPTLISRLPVVSSVACGASVGYAVSKDGRVFAWG 370

Query: 196 RGASGQLGHGEIIDRNTP 249
            G + QLG G+  D  +P
Sbjct: 371 MGTNYQLGTGQDEDAWSP 388



 Score = 36.2 bits (82), Expect = 0.043
 Identities = 28/99 (28%), Positives = 47/99 (47%), Gaps = 4/99 (4%)
 Frame = +1

Query: 4   ARGEDGKLYGWGWNKFGQVGVEDNVDHCSPVEV-NFPDEQKI-VQVACGWRHTLALTENK 177
           A   +G +YG+G + + Q+G         P  + +F +  K  V  + G  HT+ +    
Sbjct: 254 AISREGHVYGFGLSNYHQLGTPGTASCFIPQNLTSFKNSTKSWVGFSGGQHHTICMDSEG 313

Query: 178 NIFSWGRGASGQLGHGE-IIDRNTPKMIDALSLDGS-AC 288
             +S GR   G+LG GE   +++ P +I  L +  S AC
Sbjct: 314 KAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPVVSSVAC 352



 Score = 35.8 bits (81), Expect = 0.056
 Identities = 18/60 (30%), Positives = 34/60 (56%), Gaps = 2/60 (3%)
 Frame = +1

Query: 4   ARGEDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFP--DEQKIVQVACGWRHTLALTENK 177
           A  +DG+++ WG     Q+G   + D  SPVE+     + + ++ V+ G +HT+ L ++K
Sbjct: 359 AVSKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMTGKQLENRVVLTVSSGGQHTVLLVKDK 418



 Score = 35.0 bits (79), Expect = 0.095
 Identities = 23/80 (28%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
 Frame = +1

Query: 1   SARGEDGKLYGWGWNKFGQVGVEDNV-DHCSPVEVNFPDEQKIVQVACGWRHTLALTENK 177
           S + E G +   G    GQ+G+ ++V +   P  V  P  Q +VQ   G  HT+ L ++ 
Sbjct: 29  SHKTEPGLVLTLGQGDVGQLGLGESVLERKKPALV--PLLQDVVQAEAGGMHTVCLNQSG 86

Query: 178 NIFSWGRGASGQLGHGEIID 237
            ++S+G    G LG    ++
Sbjct: 87  QVYSFGCNDEGALGRDTSVE 106

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>RCC1_DROME (P25171) Regulator of chromosome condensation (Chromatin-binding|
           protein Bj1)
          Length = 547

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 39/141 (27%), Positives = 62/141 (43%), Gaps = 17/141 (12%)
 Frame = +1

Query: 37  GWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWGRGASGQL 216
           G  ++G++G+ D  D      +     +KIV V CG   + A+T +  ++SWG G + QL
Sbjct: 318 GRPEYGRLGLGDVKDVVEKPTIVKKLTEKIVSVGCGEVCSYAVTIDGKLYSWGSGVNNQL 377

Query: 217 GHGEIIDRNTPKMIDALSLDG-----------------SACKQLESSNVVPMTVKVWVSP 345
           G G+  D   P ++ + +  G                  A KQ +  N VP+ V    S 
Sbjct: 378 GVGDGDDELEPIVVVSKNTQGKHMLLASGGGQHAIFLVKADKQDQKEN-VPVKVSGSSSI 436

Query: 346 SERFALVPDENVCKSGNGTDK 408
           S++    P +NV K     DK
Sbjct: 437 SKKDKTPPQDNVDKEAENVDK 457



 Score = 32.3 bits (72), Expect = 0.62
 Identities = 18/54 (33%), Positives = 27/54 (50%), Gaps = 2/54 (3%)
 Frame = +1

Query: 16  DGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQ--KIVQVACGWRHTLALTE 171
           DGKLY WG     Q+GV D  D   P+ V   + Q   ++  + G +H + L +
Sbjct: 363 DGKLYSWGSGVNNQLGVGDGDDELEPIVVVSKNTQGKHMLLASGGGQHAIFLVK 416

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>RCC1_XENLA (P25183) Regulator of chromosome condensation|
          Length = 424

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 28/87 (32%), Positives = 47/87 (54%)
 Frame = +1

Query: 16  DGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWG 195
           +GK Y  G  ++G++G+ +N +  S      PD  KI  VA G   + A++ +  +F+WG
Sbjct: 317 EGKAYSLGRAEYGRLGLGENAEEQSE-PTPIPDLPKINSVASGASVSYAVSTDGCVFAWG 375

Query: 196 RGASGQLGHGEIIDRNTPKMIDALSLD 276
            G + QLG GE  D  +P+ +    L+
Sbjct: 376 MGTNLQLGTGEEEDVWSPEQMTGKHLE 402



 Score = 38.5 bits (88), Expect = 0.009
 Identities = 23/72 (31%), Positives = 37/72 (51%), Gaps = 2/72 (2%)
 Frame = +1

Query: 10  GEDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFS 189
           G  G +Y +G N  G +G + + +            +K+VQV+ G  HT ALTE+  +F 
Sbjct: 89  GASGSIYTFGCNDEGALGRDTSEEGSEMQPGKVELAEKVVQVSAGDSHTAALTEDGRVFV 148

Query: 190 WG--RGASGQLG 219
           +G  R  +G +G
Sbjct: 149 FGSFRDNNGVIG 160



 Score = 35.0 bits (79), Expect = 0.095
 Identities = 21/77 (27%), Positives = 40/77 (51%), Gaps = 2/77 (2%)
 Frame = +1

Query: 4   ARGEDGKLYGWGWNKFGQVGVEDNVDHCSPVEV-NFPDEQKI-VQVACGWRHTLALTENK 177
           A  ++G +YG+G + + Q+G ++     +P  + +F +  K  +  + G  HT+ +    
Sbjct: 259 AVSQEGHVYGFGLSNYHQLGTKNTQACYAPQNLTSFKNSTKSWIGFSGGQHHTVCVDSEG 318

Query: 178 NIFSWGRGASGQLGHGE 228
             +S GR   G+LG GE
Sbjct: 319 KAYSLGRAEYGRLGLGE 335



 Score = 34.7 bits (78), Expect = 0.12
 Identities = 22/68 (32%), Positives = 36/68 (52%), Gaps = 1/68 (1%)
 Frame = +1

Query: 19  GKLYGWGWNKFGQVGV-EDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWG 195
           G++   G    GQ+G+ ED ++   P  V   ++  IVQ A G  HT+ L  + +I+++G
Sbjct: 41  GQVLTLGQGDVGQLGLGEDIMERKKPALVTLTED--IVQAAAGGMHTVCLGASGSIYTFG 98

Query: 196 RGASGQLG 219
               G LG
Sbjct: 99  CNDEGALG 106

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>HIW_DROME (Q9NB71) Ubiquitin ligase protein highwire (EC 6.3.2.-) (Protein|
            pam/highwire/rpm-1)
          Length = 5233

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 26/67 (38%), Positives = 37/67 (55%)
 Frame = +1

Query: 19   GKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWGR 198
            G++Y +G N++GQ+G  D      PV V  P    I QVA G  HT+ LT    ++++G 
Sbjct: 985  GEVYTFGSNQYGQLGSGDLQPVSGPVRVQVPGA--ISQVAAGSNHTVLLTSKGMVYTFGN 1042

Query: 199  GASGQLG 219
               GQLG
Sbjct: 1043 YQKGQLG 1049



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 17/48 (35%), Positives = 27/48 (56%)
 Frame = +1

Query: 88   SPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWGRGASGQLGHGEI 231
            +P  +       +VQVACG  HT+ LT    ++++G    GQLG G++
Sbjct: 956  APQLLQLTSSSPVVQVACGLHHTVVLTLAGEVYTFGSNQYGQLGSGDL 1003

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>WBS16_HUMAN (Q96I51) Williams-Beuren syndrome chromosome region 16 protein|
          Length = 464

 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 27/78 (34%), Positives = 41/78 (52%), Gaps = 12/78 (15%)
 Frame = +1

Query: 22  KLYGWGWNKFGQVGVE----------DNVDHCSPVEVNF--PDEQKIVQVACGWRHTLAL 165
           K++G G NK  Q+G            + V   SPV +    P E +++QV+CG  H+L L
Sbjct: 130 KVWGMGLNKDSQLGFHRSRKDKTRGYEYVLEPSPVSLPLDRPQETRVLQVSCGRAHSLVL 189

Query: 166 TENKNIFSWGRGASGQLG 219
           T+ + +FS G  + GQ G
Sbjct: 190 TDREGVFSMGNNSYGQCG 207



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 28/79 (35%), Positives = 42/79 (53%), Gaps = 4/79 (5%)
 Frame = +1

Query: 25  LYGWGWNKFGQVG---VEDNVDHCSPVEVNFPD-EQKIVQVACGWRHTLALTENKNIFSW 192
           ++  G N +GQ G   VE+ +   S       D + ++VQVACG  H+L LT+   ++S 
Sbjct: 195 VFSMGNNSYGQCGRKVVENEIYSESHRVHRMQDFDGQVVQVACGQDHSLFLTDKGEVYSC 254

Query: 193 GRGASGQLGHGEIIDRNTP 249
           G GA GQ G G     ++P
Sbjct: 255 GWGADGQTGLGHYNITSSP 273



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
 Frame = +1

Query: 16  DGKLYGWGWNKFGQVG--VEDNVDHCSPVEV----NFPDEQKIVQVACGWRHTLALTENK 177
           +G ++ WG+   G+    VE  V    P  +     F  E ++ ++ CG  H  ALT   
Sbjct: 354 EGHVFVWGYGILGKGPNLVESAVPEMIPPTLFGLTEFNPEIQVSRIRCGLSHFAALTNKG 413

Query: 178 NIFSWGRGASGQLGHGEIIDRNTP 249
            +F WG+   G LG G + D+  P
Sbjct: 414 ELFVWGKNIRGCLGIGRLEDQYFP 437



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 27/83 (32%), Positives = 42/83 (50%), Gaps = 2/83 (2%)
 Frame = +1

Query: 16  DGKLYGWGWNKFGQVG-VEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSW 192
           DG L+GWG +++ Q+  V D+     P  ++F    K+ Q ACG      L    ++F W
Sbjct: 301 DGGLFGWGNSEYLQLASVTDSTQVNVPRCLHFSGVGKVRQAACGGTGCAVLNGEGHVFVW 360

Query: 193 GRGASGQLGHG-EIIDRNTPKMI 258
           G G    LG G  +++   P+MI
Sbjct: 361 GYGI---LGKGPNLVESAVPEMI 380



 Score = 29.3 bits (64), Expect = 5.2
 Identities = 19/69 (27%), Positives = 31/69 (44%), Gaps = 1/69 (1%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFP-DEQKIVQVACGWRHTLALTENKNIFS 189
           + G++Y  GW   GQ G+       SP ++        ++QVA      LA++ +  +F 
Sbjct: 247 DKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAGVNVIQVATYGDCCLAVSADGGLFG 306

Query: 190 WGRGASGQL 216
           WG     QL
Sbjct: 307 WGNSEYLQL 315



 Score = 28.5 bits (62), Expect = 8.9
 Identities = 23/84 (27%), Positives = 36/84 (42%), Gaps = 18/84 (21%)
 Frame = +1

Query: 22  KLYGWGWNKFGQVGVEDNVDHCS---------------PVEVNFPDEQKIVQVACGWRHT 156
           +++ WG++  G +GV   V   S               PV      +QKI   ACG+  T
Sbjct: 60  RVFVWGFSFSGALGVPSFVVPSSGPGPRAGARPRRRIQPVPYRLELDQKISSAACGYGFT 119

Query: 157 LALTENKNIFS-WGRGAS--GQLG 219
           L  ++  ++   WG G +   QLG
Sbjct: 120 LLSSKTADVTKVWGMGLNKDSQLG 143

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>RCC1_HUMAN (P18754) Regulator of chromosome condensation (Chromosome|
           condensation protein 1) (Cell cycle regulatory protein)
          Length = 421

 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 24/71 (33%), Positives = 41/71 (57%), Gaps = 2/71 (2%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSW 192
           + G++Y +G N  G +G + +V+    V      ++K+VQV+ G  HT ALT++  +F W
Sbjct: 84  KSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEKVVQVSAGDSHTAALTDDGRVFLW 143

Query: 193 G--RGASGQLG 219
           G  R  +G +G
Sbjct: 144 GSFRDNNGVIG 154



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 23/78 (29%), Positives = 41/78 (52%)
 Frame = +1

Query: 16  DGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWG 195
           +GK Y  G  ++G++G+ +  +  S +         +  VACG     A+T++  +F+WG
Sbjct: 312 EGKAYSLGRAEYGRLGLGEGAEEKS-IPTLISRLPAVSSVACGASVGYAVTKDGRVFAWG 370

Query: 196 RGASGQLGHGEIIDRNTP 249
            G + QLG G+  D  +P
Sbjct: 371 MGTNYQLGTGQDEDAWSP 388



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 22/76 (28%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNV-DHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFS 189
           E G +   G    GQ+G+ +NV +   P  V+ P++  +VQ   G  HT+ L+++  ++S
Sbjct: 33  EPGLVLTLGQGDVGQLGLGENVMERKKPALVSIPED--VVQAEAGGMHTVCLSKSGQVYS 90

Query: 190 WGRGASGQLGHGEIID 237
           +G    G LG    ++
Sbjct: 91  FGCNDEGALGRDTSVE 106



 Score = 35.0 bits (79), Expect = 0.095
 Identities = 17/57 (29%), Positives = 33/57 (57%), Gaps = 2/57 (3%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHCSPVEV--NFPDEQKIVQVACGWRHTLALTENK 177
           +DG+++ WG     Q+G   + D  SPVE+     + + ++ V+ G +HT+ L ++K
Sbjct: 362 KDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVKDK 418



 Score = 34.7 bits (78), Expect = 0.12
 Identities = 27/99 (27%), Positives = 47/99 (47%), Gaps = 4/99 (4%)
 Frame = +1

Query: 4   ARGEDGKLYGWGWNKFGQVGVEDNVDHCSPVEV-NFPDEQKI-VQVACGWRHTLALTENK 177
           A   +G +YG+G + + Q+G         P  + +F +  K  V  + G  HT+ +    
Sbjct: 254 AISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFSGGQHHTVCMDSEG 313

Query: 178 NIFSWGRGASGQLGHGE-IIDRNTPKMIDAL-SLDGSAC 288
             +S GR   G+LG GE   +++ P +I  L ++   AC
Sbjct: 314 KAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPAVSSVAC 352

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>RCC1_CANAL (P52499) Protein RCC1|
          Length = 464

 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 23/72 (31%), Positives = 37/72 (51%), Gaps = 7/72 (9%)
 Frame = +1

Query: 25  LYGWGWNKFGQVGV-------EDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNI 183
           +Y WG N++GQ  +       ED      P  +     + I ++A G  HTLALTE+  +
Sbjct: 272 VYAWGLNQYGQCALTGDNGELEDGSVLMKPTLIPELSHKGIKEIAAGEHHTLALTEDGQV 331

Query: 184 FSWGRGASGQLG 219
           ++WGR    ++G
Sbjct: 332 YAWGRYDMKEIG 343



 Score = 35.4 bits (80), Expect = 0.073
 Identities = 22/86 (25%), Positives = 38/86 (44%), Gaps = 11/86 (12%)
 Frame = +1

Query: 13  EDGKLYGWGWNKFGQVGVEDNVDHCSPVEVNFPDE-----------QKIVQVACGWRHTL 159
           EDG++Y WG     ++G+  +    S  ++N                KI  +  G  H+ 
Sbjct: 327 EDGQVYAWGRYDMKEIGIPKDKLPKSTFKINTGTHGSFSFLQNLFAVKIKTIGVGSHHSF 386

Query: 160 ALTENKNIFSWGRGASGQLGHGEIID 237
           A+TE+  +++WG   +   G G  ID
Sbjct: 387 AVTEDGVVYAWGFAETYGPGLGPSID 412



 Score = 33.5 bits (75), Expect = 0.28
 Identities = 20/47 (42%), Positives = 22/47 (46%)
 Frame = +1

Query: 121 KIVQVACGWRHTLALTENKNIFSWGRGASGQLGHGEIIDRNTPKMID 261
           KIV  A G  HTLAL     I+SWG   S  LG      +   K ID
Sbjct: 66  KIVDFAVGGMHTLALDGKNRIWSWGGNDSEVLGRDTCQAKEVLKDID 112

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>FBX24_MOUSE (Q9D417) F-box only protein 24|
          Length = 589

 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 24/73 (32%), Positives = 36/73 (49%)
 Frame = +1

Query: 49  FGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWGRGASGQLGHGE 228
           FG +   D +DH  P+ ++ P   K++  A G+ H   + E   IF  G    GQLG G+
Sbjct: 346 FGTLQAFDPLDHQMPLALSLP--AKVLFCALGYNHLGLVDEFGRIFMQGNNRYGQLGTGD 403

Query: 229 IIDRNTPKMIDAL 267
            +DR  P  +  L
Sbjct: 404 KMDRGEPTQVHYL 416

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>FBX24_HUMAN (O75426) F-box only protein 24|
          Length = 580

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 23/70 (32%), Positives = 34/70 (48%)
 Frame = +1

Query: 49  FGQVGVEDNVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWGRGASGQLGHGE 228
           FG +   D +D   P+ ++ P   KI+  A G+ H   + E   IF  G    GQLG G+
Sbjct: 336 FGTLQAFDPLDQQMPLALSLP--AKILFCALGYNHLGLVDEFGRIFMQGNNRYGQLGTGD 393

Query: 229 IIDRNTPKMI 258
            +DR  P  +
Sbjct: 394 KMDRGEPTQV 403

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>RCC1_CAEEL (Q18211) Regulator of chromosome condensation (Cell cycle|
           regulatory protein) (RCC1 homolog)
          Length = 569

 Score = 37.7 bits (86), Expect = 0.015
 Identities = 38/145 (26%), Positives = 59/145 (40%), Gaps = 4/145 (2%)
 Frame = +1

Query: 1   SARGEDGKLYGWG--WNKFGQVGVEDNVDHC--SPVEVNFPDEQKIVQVACGWRHTLALT 168
           +A  + G +  WG   N  G V V   +     +PV +    ++KIV++A G  H + L 
Sbjct: 257 AALTDQGSVIAWGNLRNSNGNVDVHPLLHKMQEAPVVIVHQAKRKIVKIAAGENHLVMLD 316

Query: 169 ENKNIFSWGRGASGQLGHGEIIDRNTPKMIDALSLDGSACKQLESSNVVPMTVKVWVSPS 348
           E   + ++G G  GQLG          K +         C +     +VP+  K      
Sbjct: 317 EKGCLLTFGDGEMGQLGRSSRTKTIRSKYM---------CDESGDHLLVPLRFK----HK 363

Query: 349 ERFALVPDENVCKSGNGTDKHAPEG 423
            +F  V  +NV  SG  T  H  +G
Sbjct: 364 GKFFDVVAKNVFASGFWTIVHGEDG 388



 Score = 35.8 bits (81), Expect = 0.056
 Identities = 30/103 (29%), Positives = 51/103 (49%), Gaps = 13/103 (12%)
 Frame = +1

Query: 10  GEDGKLYGWGWNKFGQVGV-----EDNVDHC---SPVEVNFPDEQKIVQVACGWRHTLAL 165
           G DGK++  G N    +G+     +D+  H    +  E+ F  + KIV V+     ++A 
Sbjct: 450 GSDGKVFAMGKNTDNALGLGNWTGKDDQQHWLYDTIQEIEF--DSKIVGVSAKLATSIAW 507

Query: 166 TENKNIFSWGRGASGQLGHGEIIDR-----NTPKMIDALSLDG 279
           +E+   ++WG   +GQLG G + D      + P+ I +  LDG
Sbjct: 508 SEDGTAYAWGFDTTGQLGLG-LKDEDEKMVSKPEEISSAHLDG 549



 Score = 35.0 bits (79), Expect = 0.095
 Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 14/86 (16%)
 Frame = +1

Query: 10  GEDGKLYGWGWNKFGQVGV--------EDNVDHCS-----PVEV-NFPDEQKIVQVACGW 147
           GEDGK Y +G N + Q+G+        +D  D+       P E   F  E+  V +  G 
Sbjct: 385 GEDGKYYAFGLNNYAQLGIKVDEADVGQDGQDNRELRVFLPAEAPAFGAERTFVNIE-GV 443

Query: 148 RHTLALTENKNIFSWGRGASGQLGHG 225
           +H + L  +  +F+ G+     LG G
Sbjct: 444 QHVVILGSDGKVFAMGKNTDNALGLG 469



 Score = 33.5 bits (75), Expect = 0.28
 Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 9/76 (11%)
 Frame = +1

Query: 16  DGKLYGWGWNKFGQV---GVEDNVDHCSPVEVNFPD----EQKIVQVACGWRHTLALTEN 174
           +G++Y  G N+ G V   GVE         +V F +    E KIV +A G   T ALT+ 
Sbjct: 203 EGEVYMCGINEKGTVPAEGVEKEGSTDEFAKVKFEEDIEKEGKIVMLAAGASFTAALTDQ 262

Query: 175 KNIFSWG--RGASGQL 216
            ++ +WG  R ++G +
Sbjct: 263 GSVIAWGNLRNSNGNV 278



 Score = 30.4 bits (67), Expect = 2.3
 Identities = 19/62 (30%), Positives = 30/62 (48%), Gaps = 6/62 (9%)
 Frame = +1

Query: 4   ARGEDGKLYGWGWNKFGQVGV----EDNVDHCSPVEVNFP--DEQKIVQVACGWRHTLAL 165
           A  EDG  Y WG++  GQ+G+    ED      P E++    D   I+  +   +HTL +
Sbjct: 506 AWSEDGTAYAWGFDTTGQLGLGLKDEDEKMVSKPEEISSAHLDGYSIIGASISDQHTLII 565

Query: 166 TE 171
            +
Sbjct: 566 AK 567

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>ATS1_YEAST (P31386) Protein ATS1 (Alpha-tubulin suppressor 1)|
          Length = 333

 Score = 33.5 bits (75), Expect = 0.28
 Identities = 22/65 (33%), Positives = 31/65 (47%), Gaps = 3/65 (4%)
 Frame = +1

Query: 16  DGKLYGWGWNKFGQVGVED---NVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIF 186
           DG L G G N+ G++        V    PVEV  P    +V VACGW  T+ +  +  ++
Sbjct: 54  DGNLVGCGDNRRGELDSAQALRQVHDWRPVEVPAP----VVDVACGWDTTVIVDADGRVW 109

Query: 187 SWGRG 201
             G G
Sbjct: 110 QRGGG 114



 Score = 33.5 bits (75), Expect = 0.28
 Identities = 20/71 (28%), Positives = 36/71 (50%), Gaps = 1/71 (1%)
 Frame = +1

Query: 25  LYGWGWNKFGQVGVEDNVDHCSPVEVNFPDEQKIVQ-VACGWRHTLALTENKNIFSWGRG 201
           +Y +G N   Q+G+  + D  +P      D+  IV+ +ACG  H++ LT + N+   G  
Sbjct: 4   VYAFGSNGQRQLGLGHDEDMDTPQRSVPGDDGAIVRKIACGGNHSVMLTNDGNLVGCGDN 63

Query: 202 ASGQLGHGEII 234
             G+L   + +
Sbjct: 64  RRGELDSAQAL 74

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>YB9W_YEAST (P38352) F-box protein YBR280C|
          Length = 637

 Score = 33.1 bits (74), Expect = 0.36
 Identities = 16/41 (39%), Positives = 26/41 (63%)
 Frame = +1

Query: 73  NVDHCSPVEVNFPDEQKIVQVACGWRHTLALTENKNIFSWG 195
           +VD  S  E++    + ++ VA G  HT+ALTE  +++SWG
Sbjct: 533 DVDKDSLTELDI--NENVISVASGDYHTVALTERGHLYSWG 571

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>WRK42_ARATH (Q9XEC3) Probable WRKY transcription factor 42 (WRKY DNA-binding|
           protein 42)
          Length = 528

 Score = 30.0 bits (66), Expect = 3.1
 Identities = 16/56 (28%), Positives = 27/56 (48%), Gaps = 5/56 (8%)
 Frame = +3

Query: 171 KQEYFLMGQGCQWTAWSW*NNRQEHAQDDRCPKPGRVCLQAVGV-----IKRCSND 323
           + E  ++  GCQW  +      Q+ A+ + CP+    C  AVG      ++RC+ D
Sbjct: 285 RSEAPMLSDGCQWRKYG-----QKMAKGNPCPRAYYRCTMAVGCPVRKQVQRCAED 335

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>WRK47_ARATH (Q9ZSI7) Probable WRKY transcription factor 47 (WRKY DNA-binding|
           protein 47)
          Length = 489

 Score = 30.0 bits (66), Expect = 3.1
 Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 5/58 (8%)
 Frame = +3

Query: 189 MGQGCQWTAWSW*NNRQEHAQDDRCPKPGRVCLQAVGV-----IKRCSNDS*SLGLTF 347
           +  GCQW  +      Q+ A+ + CP+    C  AVG      ++RC+ D+  L  T+
Sbjct: 238 VNDGCQWRKYG-----QKMAKGNPCPRAYYRCTMAVGCPVRKQVQRCAEDTTILTTTY 290

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>UPL1_ARATH (Q8GY23) E3 ubiquitin protein ligase UPL1 (EC 6.3.2.-)|
           (Ubiquitin-protein ligase 1)
          Length = 3684

 Score = 30.0 bits (66), Expect = 3.1
 Identities = 15/42 (35%), Positives = 24/42 (57%)
 Frame = +1

Query: 247 PKMIDALSLDGSACKQLESSNVVPMTVKVWVSPSERFALVPD 372
           P+ +DAL L+ S  + ++  N +   VK++ SPS   AL  D
Sbjct: 587 PQCLDALCLNNSGLQAVKDRNALRCFVKIFTSPSYLRALTGD 628

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>UPL2_ARATH (Q8H0T4) E3 ubiquitin protein ligase UPL2 (EC 6.3.2.-)|
           (Ubiquitin-protein ligase 2)
          Length = 3658

 Score = 29.6 bits (65), Expect = 4.0
 Identities = 15/42 (35%), Positives = 24/42 (57%)
 Frame = +1

Query: 247 PKMIDALSLDGSACKQLESSNVVPMTVKVWVSPSERFALVPD 372
           P+ +DAL L+ S  + ++  N +   VK++ SPS   AL  D
Sbjct: 589 PQCLDALCLNNSGLQAVKDRNALRCFVKIFSSPSYLKALTSD 630

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>LCTL_MOUSE (Q8K1F9) Lactase-like protein precursor (Klotho/lactase-phlorizin|
           hydrolase-related protein)
          Length = 566

 Score = 28.9 bits (63), Expect = 6.8
 Identities = 13/42 (30%), Positives = 22/42 (52%), Gaps = 4/42 (9%)
 Frame = +1

Query: 34  WGWNKFGQVGVEDNVDHCSPVEVNFPDE----QKIVQVACGW 147
           W   + G VG+  N D   PV+++ PD+    ++ +Q   GW
Sbjct: 247 WRSKQHGLVGISLNCDWGEPVDIDNPDDIEAAERYLQFCLGW 288

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>YBBS_ECOLI (P0ACR0) Putative HTH-type transcriptional regulator ybbS|
          Length = 308

 Score = 28.9 bits (63), Expect = 6.8
 Identities = 15/36 (41%), Positives = 22/36 (61%)
 Frame = +2

Query: 110 LTNRKLYRLPVDGGILLP*QKTRIFSHGAGVPVDSL 217
           LT R  +RLP    I++P  +T+I +H AGV +  L
Sbjct: 206 LTKRVAWRLPGQKEIIVPDMETKIAAHLAGVGIGFL 241

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>YBBS_ECO57 (P0ACR1) Putative HTH-type transcriptional regulator ybbS|
          Length = 308

 Score = 28.9 bits (63), Expect = 6.8
 Identities = 15/36 (41%), Positives = 22/36 (61%)
 Frame = +2

Query: 110 LTNRKLYRLPVDGGILLP*QKTRIFSHGAGVPVDSL 217
           LT R  +RLP    I++P  +T+I +H AGV +  L
Sbjct: 206 LTKRVAWRLPGQKEIIVPDMETKIAAHLAGVGIGFL 241

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>YR335_MIMIV (Q5UQT2) Hypothetical protein R335|
          Length = 306

 Score = 28.9 bits (63), Expect = 6.8
 Identities = 13/36 (36%), Positives = 18/36 (50%)
 Frame = -3

Query: 142 HRQPVQFSVRQENSPLRGNSDLRYLQHQLGQTCSTP 35
           H+QP QF+  Q N P + N   +Y QH      + P
Sbjct: 149 HQQPNQFTQNQPNQPNQPNQHNQYSQHNQPNQSNQP 184

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>KPC2_CAEEL (P90980) Protein kinase C-like 2 (EC 2.7.11.13) (PKC2)|
          Length = 682

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 14/43 (32%), Positives = 22/43 (51%)
 Frame = +1

Query: 274 DGSACKQLESSNVVPMTVKVWVSPSERFALVPDENVCKSGNGT 402
           D    K LE+ N++PM       P  +  L+P+++ CKS   T
Sbjct: 173 DQLTIKILEAKNLIPMDPNGLSDPYVKCKLIPEDSGCKSKQKT 215

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>WRK25_ARATH (O22921) Probable WRKY transcription factor 25 (WRKY DNA-binding|
           protein 25)
          Length = 393

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 14/38 (36%), Positives = 23/38 (60%), Gaps = 2/38 (5%)
 Frame = +1

Query: 31  GWGWNKFGQVGVEDNVDHCSPVEVNFPD--EQKIVQVA 138
           G+GW K+GQ  V+ + +  S  +  +PD   +KIV+ A
Sbjct: 168 GYGWRKYGQKQVKKSENPRSYFKCTYPDCVSKKIVETA 205


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 75,438,478
Number of Sequences: 219361
Number of extensions: 1662602
Number of successful extensions: 4861
Number of sequences better than 10.0: 59
Number of HSP's better than 10.0 without gapping: 4446
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4791
length of database: 80,573,946
effective HSP length: 103
effective length of database: 57,979,763
effective search space used: 3014947676
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

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full-length cDNA and EST

Clone Information

BLAST Search Result