ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bags6n08 |
|---|---|
| Clone Library Name | barley_pub |
>KPYC_TOBAC (Q42954) Pyruvate kinase, cytosolic isozyme (EC 2.7.1.40) (PK)| Length = 508 Score = 328 bits (842), Expect(2) = 7e-90 Identities = 170/203 (83%), Positives = 182/203 (89%) Frame = +3 Query: 51 KVLGEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIF 230 K+LGEHAK+I+LMSKVENQEGVANFDDIL SDAFMVARGDLGMEIP+EKIF AQKVMI+ Sbjct: 224 KLLGEHAKNILLMSKVENQEGVANFDDILLNSDAFMVARGDLGMEIPIEKIFLAQKVMIY 283 Query: 231 KCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAV 410 KCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYP+LAV Sbjct: 284 KCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPDLAV 343 Query: 411 QTMAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGG 590 TMAKIC++AES +DY VFK LESLASSAVRTANSAKA LILVLTRGG Sbjct: 344 GTMAKICIEAESTIDYPDVFKRIMSNAPVPMSPLESLASSAVRTANSAKAALILVLTRGG 403 Query: 591 TTARLVAKYRPSMPILSVVVPEL 659 +TA+LVAKYRP MPILSVVVPE+ Sbjct: 404 STAKLVAKYRPGMPILSVVVPEI 426 Score = 22.3 bits (46), Expect(2) = 7e-90 Identities = 10/10 (100%), Positives = 10/10 (100%) Frame = +1 Query: 1 IALSFVRKGS 30 IALSFVRKGS Sbjct: 208 IALSFVRKGS 217
>KPYC_ARATH (O65595) Probable pyruvate kinase, cytosolic isozyme (EC 2.7.1.40)| (PK) Length = 497 Score = 319 bits (817), Expect(2) = 5e-87 Identities = 161/203 (79%), Positives = 181/203 (89%) Frame = +3 Query: 51 KVLGEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIF 230 K+LG+HAK+I+LMSKVENQEGVANFDDIL SDAFM+ARGDLGMEIP+EKIF AQKVMI+ Sbjct: 213 KLLGKHAKTILLMSKVENQEGVANFDDILINSDAFMIARGDLGMEIPIEKIFLAQKVMIY 272 Query: 231 KCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAV 410 KCN GKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAV Sbjct: 273 KCNFMGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAV 332 Query: 411 QTMAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGG 590 +TMAKIC++AES +DY +FK +ESLASSAVRTA S++ATL++VLTRGG Sbjct: 333 RTMAKICVEAESTLDYGDIFKRIMLHAAVPMSPMESLASSAVRTATSSRATLMMVLTRGG 392 Query: 591 TTARLVAKYRPSMPILSVVVPEL 659 +TARLVAKYRP +PILSVVVPE+ Sbjct: 393 STARLVAKYRPGIPILSVVVPEI 415 Score = 22.3 bits (46), Expect(2) = 5e-87 Identities = 10/10 (100%), Positives = 10/10 (100%) Frame = +1 Query: 1 IALSFVRKGS 30 IALSFVRKGS Sbjct: 197 IALSFVRKGS 206
>KPYC_SOYBN (Q42806) Pyruvate kinase, cytosolic isozyme (EC 2.7.1.40) (PK)| Length = 511 Score = 311 bits (797), Expect(2) = 1e-84 Identities = 160/203 (78%), Positives = 179/203 (88%) Frame = +3 Query: 51 KVLGEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIF 230 KVLG HAK+I LMSKVENQEGV NFD+IL ++DAFMVARGDLGMEIPVEKIF AQK+MI+ Sbjct: 227 KVLGPHAKNIQLMSKVENQEGVLNFDEILRETDAFMVARGDLGMEIPVEKIFLAQKMMIY 286 Query: 231 KCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAV 410 KCN+ GKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGE+AAGAYPELAV Sbjct: 287 KCNLVGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAGAYPELAV 346 Query: 411 QTMAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGG 590 + MA+IC++AES +DY A+FK LESLASSAVRTAN AKA LI+VLTRGG Sbjct: 347 KIMARICIEAESSLDYGAIFKEMIRSTPLPMSPLESLASSAVRTANKAKAKLIVVLTRGG 406 Query: 591 TTARLVAKYRPSMPILSVVVPEL 659 +TA+LVAKYRP++PILSVVVP L Sbjct: 407 STAKLVAKYRPAVPILSVVVPVL 429 Score = 22.3 bits (46), Expect(2) = 1e-84 Identities = 10/10 (100%), Positives = 10/10 (100%) Frame = +1 Query: 1 IALSFVRKGS 30 IALSFVRKGS Sbjct: 211 IALSFVRKGS 220
>KPYC_SOLTU (P22200) Pyruvate kinase, cytosolic isozyme (EC 2.7.1.40) (PK)| Length = 510 Score = 298 bits (762), Expect(2) = 1e-80 Identities = 154/203 (75%), Positives = 175/203 (86%) Frame = +3 Query: 51 KVLGEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIF 230 KVLG HAK I LMSKVENQEGV NFD+IL ++D+FMVARGDLGMEIPVEKIF AQK+MI+ Sbjct: 226 KVLGPHAKRIQLMSKVENQEGVINFDEILRETDSFMVARGDLGMEIPVEKIFLAQKMMIY 285 Query: 231 KCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAV 410 KCN+ GK VVTATQMLESMIKSP PTRAEATDVANAVLDGTDCVMLSGE+AAGAYPELAV Sbjct: 286 KCNLAGKAVVTATQMLESMIKSPAPTRAEATDVANAVLDGTDCVMLSGESAAGAYPELAV 345 Query: 411 QTMAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGG 590 + M++IC++AES +D A+FK LESLASSAVRTAN A+A LI+VLTRGG Sbjct: 346 KIMSRICIEAESSLDNEAIFKEMIRCTPLPMSPLESLASSAVRTANKARAKLIVVLTRGG 405 Query: 591 TTARLVAKYRPSMPILSVVVPEL 659 +TA+LVAKYRP++PILSVVVP L Sbjct: 406 STAKLVAKYRPAVPILSVVVPVL 428 Score = 22.3 bits (46), Expect(2) = 1e-80 Identities = 10/10 (100%), Positives = 10/10 (100%) Frame = +1 Query: 1 IALSFVRKGS 30 IALSFVRKGS Sbjct: 210 IALSFVRKGS 219
>KPYK_EIMTE (O44006) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 531 Score = 243 bits (620), Expect = 4e-64 Identities = 118/201 (58%), Positives = 149/201 (74%) Frame = +3 Query: 54 VLGEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIFK 233 +LG ++I ++ K+EN EG+ NFD+IL ++D M+ARGDLGMEIP EK+F AQK+MI K Sbjct: 262 ILGTKGRNIKIIPKIENVEGLLNFDEILQEADGIMIARGDLGMEIPPEKVFLAQKMMISK 321 Query: 234 CNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAVQ 413 CN+ GKPV+TATQMLESM K+PRPTRAEA DVANAVLDGTDCVMLSGETA G++P AV Sbjct: 322 CNVAGKPVITATQMLESMTKNPRPTRAEAADVANAVLDGTDCVMLSGETANGSFPVQAVT 381 Query: 414 TMAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGGT 593 M+++C +AE C+DY VF+ E++A +AV TA S A+LIL LT G Sbjct: 382 VMSRVCFEAEGCIDYQQVFRATCQATMTPIDTQEAVARAAVETAQSINASLILALTETGR 441 Query: 594 TARLVAKYRPSMPILSVVVPE 656 TARL+AKYRP PIL++ E Sbjct: 442 TARLIAKYRPMQPILALSASE 462
>KPYK_ASPNG (Q12669) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 526 Score = 216 bits (550), Expect = 5e-56 Identities = 111/198 (56%), Positives = 140/198 (70%) Frame = +3 Query: 51 KVLGEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIF 230 +VLGE K I +++K+ENQ+GV NFD+IL ++D MVARGDLG+EIP K+F AQK+MI Sbjct: 240 EVLGEEGKEIQIIAKIENQQGVNNFDEILEETDGVMVARGDLGIEIPAPKVFIAQKMMIA 299 Query: 231 KCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAV 410 KCNI+GKPV+ ATQMLESM +PRPTRAE +DVANAVLDG DCVMLSGETA G YP AV Sbjct: 300 KCNIKGKPVICATQMLESMTYNPRPTRAEVSDVANAVLDGADCVMLSGETAKGNYPNEAV 359 Query: 411 QTMAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGG 590 + M++ CL AE + + VF +ES+A +AV + A I+VLT G Sbjct: 360 KMMSETCLLAEVAIPHFNVFDELRNLAPRPTDTVESIAMAAVSASLELNAGAIVVLTTSG 419 Query: 591 TTARLVAKYRPSMPILSV 644 TAR ++KYRP PI+ V Sbjct: 420 KTARYLSKYRPVCPIVMV 437
>KPYK_EMENI (P22360) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 526 Score = 215 bits (548), Expect = 8e-56 Identities = 110/198 (55%), Positives = 140/198 (70%) Frame = +3 Query: 51 KVLGEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIF 230 +VLGE + I +++K+ENQ+GV NFD+IL ++D MVARGDLG+EIP K+F AQK+MI Sbjct: 240 EVLGEEGREIQIIAKIENQQGVNNFDEILEETDGVMVARGDLGIEIPAPKVFIAQKMMIA 299 Query: 231 KCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAV 410 KCNI+GKPV+ ATQMLESM +PRPTRAE +DVANAVLDG DCVMLSGETA G YP AV Sbjct: 300 KCNIKGKPVICATQMLESMTYNPRPTRAEVSDVANAVLDGADCVMLSGETAKGNYPCEAV 359 Query: 411 QTMAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGG 590 M++ CL AE + + VF +ES+A +AV + A I+VLT G Sbjct: 360 TMMSETCLLAEVAIPHFNVFDELRNLAPRPTDTVESIAMAAVSASLELNAGAIVVLTTSG 419 Query: 591 TTARLVAKYRPSMPILSV 644 TAR+++KYRP PI+ V Sbjct: 420 NTARMISKYRPVCPIIMV 437
>KPYK_AGABI (O94122) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 532 Score = 215 bits (548), Expect = 8e-56 Identities = 109/198 (55%), Positives = 142/198 (71%) Frame = +3 Query: 51 KVLGEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIF 230 +VLG SI ++ K+EN++GVANFD+IL ++D MVARGDLG+EIP ++F AQK+MI Sbjct: 240 EVLGPDGASIKIIVKIENEQGVANFDEILKEADGVMVARGDLGIEIPASQVFLAQKMMIA 299 Query: 231 KCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAV 410 KCNI GKPV+ ATQMLESM +PRPTRAE +DVANAVLDG+DCVMLSGETA G+YP +V Sbjct: 300 KCNIVGKPVIVATQMLESMTYNPRPTRAEVSDVANAVLDGSDCVMLSGETAKGSYPVQSV 359 Query: 411 QTMAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGG 590 MA+ CL AE+ + Y ++ E++A +AV A A +LVL+ G Sbjct: 360 LMMAETCLLAETAICYPPLYDDLRAVQARPTETAETVAIAAVAAAAEQDAKALLVLSTSG 419 Query: 591 TTARLVAKYRPSMPILSV 644 TARLV+KYRP +PI++V Sbjct: 420 ETARLVSKYRPKIPIITV 437
>KPYK_YARLI (P30614) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 515 Score = 213 bits (541), Expect = 5e-55 Identities = 107/197 (54%), Positives = 139/197 (70%) Frame = +3 Query: 54 VLGEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIFK 233 VLGE K I ++SK+ENQ+GV NFD+IL ++D MVARGDLG+EIP ++F AQK +I K Sbjct: 238 VLGEKGKGIQVISKIENQQGVNNFDEILKETDGVMVARGDLGIEIPAPQVFIAQKQLIAK 297 Query: 234 CNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAVQ 413 CN+ GKPV+ ATQML+SM +PRPTRAE +DV NAVLDG DCVMLSGETA G YP +V+ Sbjct: 298 CNLAGKPVICATQMLDSMTYNPRPTRAEVSDVGNAVLDGADCVMLSGETAKGTYPIESVK 357 Query: 414 TMAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGGT 593 M + CL AE + Y+ +F +E++A SAV + +A I+VL+ GT Sbjct: 358 MMHETCLVAEKAIAYAPLFNEMRTLTVRPTETVETIAISAVSASFEQQARAIIVLSTSGT 417 Query: 594 TARLVAKYRPSMPILSV 644 +ARL +KYRP+ PIL V Sbjct: 418 SARLCSKYRPNCPILMV 434
>KPYM_RAT (P11980) Pyruvate kinase isozymes M1/M2 (EC 2.7.1.40) (Pyruvate| kinase muscle isozyme) Length = 530 Score = 211 bits (536), Expect = 2e-54 Identities = 108/198 (54%), Positives = 136/198 (68%) Frame = +3 Query: 51 KVLGEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIF 230 KVLGE K+I ++SK+EN EGV FD+IL SD MVARGDLG+EIP EK+F AQK+MI Sbjct: 255 KVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIG 314 Query: 231 KCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAV 410 +CN GKPV+ ATQMLESMIK PRPTRAE +DVANAVLDG DC+MLSGETA G YP AV Sbjct: 315 RCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAV 374 Query: 411 QTMAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGG 590 + I +AE+ V + +F+ LE++A +V + A ++VLT G Sbjct: 375 RMQHLIAREAEAAVFHRLLFEELARASSQSTDPLEAMAMGSVEASYKCLAAALIVLTESG 434 Query: 591 TTARLVAKYRPSMPILSV 644 +A VA+YRP PI++V Sbjct: 435 RSAHQVARYRPRAPIIAV 452
>KPYK_DROME (O62619) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 533 Score = 210 bits (534), Expect = 3e-54 Identities = 109/198 (55%), Positives = 137/198 (69%) Frame = +3 Query: 51 KVLGEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIF 230 KVLGE K+I ++SK+ENQ+G+ N D+I+ D MVARGDLG+EIP EK+F AQK MI Sbjct: 259 KVLGEKGKNIKIISKIENQQGMHNLDEIIEAGDGIMVARGDLGIEIPAEKVFLAQKAMIA 318 Query: 231 KCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAV 410 +CN GKPV+ ATQMLESM+K PRPTRAE +DVANAVLDG DCVMLSGETA G YP V Sbjct: 319 RCNKAGKPVICATQMLESMVKKPRPTRAEISDVANAVLDGADCVMLSGETAKGEYPLECV 378 Query: 411 QTMAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGG 590 TMAK C +AE+ + + +F + A +AV A AKA+ I+V+T G Sbjct: 379 LTMAKTCKEAEAALWHQNLFNDLVRGAGTIDAS-HAAAIAAVEAATKAKASAIVVITTSG 437 Query: 591 TTARLVAKYRPSMPILSV 644 +A V+KYRP PI++V Sbjct: 438 KSAFQVSKYRPRCPIIAV 455
>KPYK_LEIME (Q27686) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 499 Score = 209 bits (533), Expect = 5e-54 Identities = 105/198 (53%), Positives = 135/198 (68%) Frame = +3 Query: 51 KVLGEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIF 230 K LG + IM++ K+EN +GV N D I+ +SD MVARGDLG+EIP EK+ AQK++I Sbjct: 225 KALGPKGRDIMIICKIENHQGVQNIDSIIEESDGIMVARGDLGVEIPAEKVVVAQKILIS 284 Query: 231 KCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAV 410 KCN+ GKPV+ ATQMLESM +PRPTRAE +DVANAV +G DCVMLSGETA G YP V Sbjct: 285 KCNVAGKPVICATQMLESMTYNPRPTRAEVSDVANAVFNGADCVMLSGETAKGKYPNEVV 344 Query: 411 QTMAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGG 590 Q MA+ICL+A+S ++ F E++ SAV + + KA ++VL+ G Sbjct: 345 QYMARICLEAQSALNEYVFFNSIKKLQHIPMSADEAVCGSAVNSVSETKAKAMVVLSNTG 404 Query: 591 TTARLVAKYRPSMPILSV 644 ARLVAKYRP+ PI+ V Sbjct: 405 AGARLVAKYRPNCPIVCV 422
>KPYM_FELCA (P11979) Pyruvate kinase isozyme M1 (EC 2.7.1.40) (Pyruvate kinase| muscle isozyme) Length = 530 Score = 208 bits (530), Expect = 1e-53 Identities = 106/198 (53%), Positives = 136/198 (68%) Frame = +3 Query: 51 KVLGEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIF 230 KVLGE K+I ++SK+EN EGV FD+IL SD MVARGDLG+EIP EK+F AQK+MI Sbjct: 255 KVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIG 314 Query: 231 KCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAV 410 +CN GKPV+ ATQMLESMIK PRPTRAE +DVANAVLDG DC+MLSGETA G YP AV Sbjct: 315 RCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAV 374 Query: 411 QTMAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGG 590 + I +AE+ + + +F+ +E++A +V + A ++VLT G Sbjct: 375 RMQHLIAREAEAAMFHRKLFEELVRGSSHSTDLMEAMAMGSVEASYKCLAAALIVLTESG 434 Query: 591 TTARLVAKYRPSMPILSV 644 +A VA+YRP PI++V Sbjct: 435 RSAHQVARYRPRAPIIAV 452
>KPYK_NEUCR (Q7RVA8) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 527 Score = 207 bits (528), Expect = 2e-53 Identities = 105/198 (53%), Positives = 141/198 (71%) Frame = +3 Query: 51 KVLGEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIF 230 +VLGE K I +++K+EN++G+ NF +ILA++D MVARGDLG+EIP ++F AQK +I Sbjct: 239 EVLGEDGKQIQIIAKIENRQGLNNFAEILAETDGVMVARGDLGIEIPAAEVFAAQKKIIA 298 Query: 231 KCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAV 410 CNI GKPV+ ATQMLESMIK+PRPTRAE +DV NAV DG DCVMLSGETA GAYP AV Sbjct: 299 MCNIAGKPVICATQMLESMIKNPRPTRAEISDVGNAVTDGADCVMLSGETAKGAYPTEAV 358 Query: 411 QTMAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGG 590 + M++ L+AE+ + Y + F+ +ES A ++VR + A ILVL+ G Sbjct: 359 REMSEAVLKAENTIPYVSHFEELCSLAKRPVSIVESCAMASVRASLDLNAAAILVLSTSG 418 Query: 591 TTARLVAKYRPSMPILSV 644 +ARL++KYRP PI+ + Sbjct: 419 ESARLISKYRPVCPIIMI 436
>KPYM_RABIT (P11974) Pyruvate kinase isozymes M1/M2 (EC 2.7.1.40) (Pyruvate| kinase muscle isozyme) Length = 530 Score = 207 bits (527), Expect = 2e-53 Identities = 104/198 (52%), Positives = 136/198 (68%) Frame = +3 Query: 51 KVLGEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIF 230 K+LGE K+I ++SK+EN EGV FD+IL SD MVARGDLG+EIP EK+F AQK++I Sbjct: 255 KILGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMIIG 314 Query: 231 KCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAV 410 +CN GKPV+ ATQMLESMIK PRPTRAE +DVANAVLDG DC+MLSGETA G YP AV Sbjct: 315 RCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAV 374 Query: 411 QTMAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGG 590 + I +AE+ + + +F+ +E++A +V + A ++VLT G Sbjct: 375 RMQHLIAREAEAAMFHRKLFEELARSSSHSTDLMEAMAMGSVEASYKCLAAALIVLTESG 434 Query: 591 TTARLVAKYRPSMPILSV 644 +A VA+YRP PI++V Sbjct: 435 RSAHQVARYRPRAPIIAV 452
>KPYK_XENLA (Q92122) Pyruvate kinase muscle isozyme (EC 2.7.1.40) (Cytosolic| thyroid hormone-binding protein) (CTHBP) Length = 527 Score = 206 bits (524), Expect = 5e-53 Identities = 106/198 (53%), Positives = 136/198 (68%) Frame = +3 Query: 51 KVLGEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIF 230 +VLGE K+I ++SK+EN EGV FD+IL SD MVARGDLG+EIP EK+F AQK+MI Sbjct: 252 EVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIG 311 Query: 231 KCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAV 410 +CN GKPV+ ATQMLESMIK PRPTRAE +DVANAVLDG DC+MLSGETA G YP AV Sbjct: 312 RCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAV 371 Query: 411 QTMAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGG 590 + I +AE+ + + +F+ E+ A AV + + I+VLT+ G Sbjct: 372 RMQHAIAREAEAAIFHRQLFEELRRVSPLTRDPTEATAVGAVEASFKCSSGAIIVLTKSG 431 Query: 591 TTARLVAKYRPSMPILSV 644 +A L+++YRP PI+SV Sbjct: 432 RSAHLLSRYRPRAPIISV 449
>KPYM_PONPY (Q5NVN0) Pyruvate kinase isozyme M1 (EC 2.7.1.40)| Length = 530 Score = 206 bits (524), Expect = 5e-53 Identities = 105/198 (53%), Positives = 135/198 (68%) Frame = +3 Query: 51 KVLGEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIF 230 KVLGE K+I ++SK+EN EGV FD+IL SD MVARGDLG+EIP EK+F AQK+MI Sbjct: 255 KVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIG 314 Query: 231 KCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAV 410 +CN GKPV+ ATQMLESMIK PRPTRAE + VANAVLDG DC+MLSGETA G YP AV Sbjct: 315 RCNRAGKPVICATQMLESMIKKPRPTRAEGSGVANAVLDGADCIMLSGETAKGDYPLEAV 374 Query: 411 QTMAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGG 590 + I +AE+ + + +F+ +E++A +V + A ++VLT G Sbjct: 375 RMQHLIAREAEAAMFHRKLFEELVRASSHSTDLMEAMAMGSVEASYKCLAAALIVLTESG 434 Query: 591 TTARLVAKYRPSMPILSV 644 +A VA+YRP PI++V Sbjct: 435 RSAHQVARYRPRAPIIAV 452
>KPYK_ASHGO (Q759A9) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 501 Score = 206 bits (523), Expect = 7e-53 Identities = 104/198 (52%), Positives = 137/198 (69%) Frame = +3 Query: 51 KVLGEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIF 230 ++LGE K I +++K+ENQ+GV NFD+IL +D MVARGDLG+EIP ++F QK++I Sbjct: 227 EILGEDGKDIKIIAKIENQQGVNNFDEILKVTDGVMVARGDLGIEIPAPQVFAVQKMLIA 286 Query: 231 KCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAV 410 KCN+ GKPV+ ATQMLESM +PRPTRAE +DV NAVLDG DCVMLSGETA G YP AV Sbjct: 287 KCNLAGKPVICATQMLESMTYNPRPTRAEVSDVGNAVLDGADCVMLSGETAKGIYPINAV 346 Query: 411 QTMAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGG 590 +TMA+ L AE + Y + E++A++AV KA I+VL+ G Sbjct: 347 KTMAETALIAEQAIPYVPTYDDLRNLTPKPTPTSETIAAAAVAATFEQKAKAIVVLSTSG 406 Query: 591 TTARLVAKYRPSMPILSV 644 T RLV+KY+P++PI+ V Sbjct: 407 DTTRLVSKYKPNVPIVMV 424
>KPYK_KLULA (Q875M9) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 501 Score = 205 bits (521), Expect = 1e-52 Identities = 105/198 (53%), Positives = 135/198 (68%) Frame = +3 Query: 51 KVLGEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIF 230 +VLGE K I ++ K+ENQ+GV NFDDIL +D MVARGDLG+EIP ++F QK +I Sbjct: 227 EVLGEQGKDIKIIVKIENQQGVNNFDDILKVTDGVMVARGDLGIEIPAPQVFAVQKKLIA 286 Query: 231 KCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAV 410 KCN+ GKPV+ ATQMLESM +PRPTRAE +DV NAVLDG DCVMLSGETA G YP AV Sbjct: 287 KCNLAGKPVICATQMLESMTYNPRPTRAEVSDVGNAVLDGADCVMLSGETAKGNYPINAV 346 Query: 411 QTMAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGG 590 +TMA+ L AE + Y + E++A+++V KA ++VL+ G Sbjct: 347 KTMAETALIAEQAIPYIPTYDDLRNLTPKPTSTTETIAAASVSAVFEQKARALIVLSTTG 406 Query: 591 TTARLVAKYRPSMPILSV 644 T RLVAKY+P++PI+ V Sbjct: 407 DTPRLVAKYKPNVPIVMV 424
>KPYM_HUMAN (P14618) Pyruvate kinase isozymes M1/M2 (EC 2.7.1.40) (Pyruvate| kinase muscle isozyme) (Cytosolic thyroid hormone-binding protein) (CTHBP) (THBP1) Length = 530 Score = 205 bits (521), Expect = 1e-52 Identities = 107/198 (54%), Positives = 135/198 (68%) Frame = +3 Query: 51 KVLGEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIF 230 KVLGE K+I ++SK+EN EGV FD+IL SD MVARGDLG+EIP EK+F AQK+MI Sbjct: 255 KVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIG 314 Query: 231 KCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAV 410 +CN GKPV+ ATQMLESMIK PRPTRAE +DVANAVLDG DC+MLSGETA G YP AV Sbjct: 315 RCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAV 374 Query: 411 QTMAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGG 590 + I +AE+ + + +F+ E+ A AV + + I+VLT+ G Sbjct: 375 RMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCCSGAIIVLTKSG 434 Query: 591 TTARLVAKYRPSMPILSV 644 +A VA+YRP PI++V Sbjct: 435 RSAHQVARYRPRAPIIAV 452
>KPYK2_TRYBB (P30616) Pyruvate kinase 2 (EC 2.7.1.40) (PK 2)| Length = 499 Score = 204 bits (520), Expect = 1e-52 Identities = 104/196 (53%), Positives = 136/196 (69%) Frame = +3 Query: 57 LGEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIFKC 236 LGE K I+++SK+EN +GV N D I+ S+ MVARGDLG+EIP EK+ AQ +I KC Sbjct: 227 LGEKGKDILIISKIENHQGVQNIDSIIEASNGIMVARGDLGVEIPAEKVCVAQMCIISKC 286 Query: 237 NIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAVQT 416 N+ GKPV+ ATQMLESM +PRPTRAE +DVANAVL+G DCVMLSGETA G YP VQ Sbjct: 287 NVVGKPVICATQMLESMTSNPRPTRAEVSDVANAVLNGADCVMLSGETAKGKYPNEVVQY 346 Query: 417 MAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGGTT 596 MA+IC++A+S + +F E++ SSAV +A +A +LVL+ G + Sbjct: 347 MARICVEAQSATHDTVMFNSIKNLQKIPMCPEEAVCSSAVASAFEVQAKAMLVLSNTGRS 406 Query: 597 ARLVAKYRPSMPILSV 644 ARL++KYRP+ PI+ V Sbjct: 407 ARLISKYRPNCPIICV 422
>KPYK1_TRYBB (P30615) Pyruvate kinase 1 (EC 2.7.1.40) (PK 1)| Length = 499 Score = 204 bits (520), Expect = 1e-52 Identities = 104/196 (53%), Positives = 136/196 (69%) Frame = +3 Query: 57 LGEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIFKC 236 LGE K I+++SK+EN +GV N D I+ S+ MVARGDLG+EIP EK+ AQ +I KC Sbjct: 227 LGEKGKDILIISKIENHQGVQNIDSIIEASNGIMVARGDLGVEIPAEKVCVAQMCIISKC 286 Query: 237 NIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAVQT 416 N+ GKPV+ ATQMLESM +PRPTRAE +DVANAVL+G DCVMLSGETA G YP VQ Sbjct: 287 NVVGKPVICATQMLESMTSNPRPTRAEVSDVANAVLNGADCVMLSGETAKGKYPNEVVQY 346 Query: 417 MAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGGTT 596 MA+IC++A+S + +F E++ SSAV +A +A +LVL+ G + Sbjct: 347 MARICVEAQSATHDTVMFNSIKNLQKIPMCPEEAVCSSAVASAFEVQAKAMLVLSNTGRS 406 Query: 597 ARLVAKYRPSMPILSV 644 ARL++KYRP+ PI+ V Sbjct: 407 ARLISKYRPNCPIICV 422
>KPYK_CHICK (P00548) Pyruvate kinase muscle isozyme (EC 2.7.1.40)| Length = 529 Score = 204 bits (518), Expect = 2e-52 Identities = 103/198 (52%), Positives = 135/198 (68%) Frame = +3 Query: 51 KVLGEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIF 230 KVLGE K I ++SK+EN EGV FD+I+ SD MVARGDLG+EIP EK+F AQK+MI Sbjct: 254 KVLGEKGKHIKIISKIENHEGVRRFDEIMEASDGIMVARGDLGIEIPAEKVFLAQKMMIG 313 Query: 231 KCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAV 410 +CN GKP++ ATQMLESMIK PRPTRAE +DVANAVLDG DC+MLSGETA G YP AV Sbjct: 314 RCNRAGKPIICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAV 373 Query: 411 QTMAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGG 590 + I +AE+ + + F+ +++A+ AV + A ++V+T G Sbjct: 374 RMQHAIAREAEAAMFHRQQFEEILRHSVHHREPADAMAAGAVEASFKCLAAALIVMTESG 433 Query: 591 TTARLVAKYRPSMPILSV 644 +A LV++YRP PI++V Sbjct: 434 RSAHLVSRYRPRAPIIAV 451
>KPYK_SACKL (Q875S4) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 501 Score = 202 bits (515), Expect = 6e-52 Identities = 104/198 (52%), Positives = 135/198 (68%) Frame = +3 Query: 51 KVLGEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIF 230 +VLGE K + ++ K+ENQ+GV NFD+IL +D MVARGDLG+EIP ++F QK +I Sbjct: 227 EVLGEDGKDVKIIVKIENQQGVNNFDEILKVTDGVMVARGDLGIEIPAPQVFAVQKKLIA 286 Query: 231 KCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAV 410 KCN+ GKPV+ ATQMLESM +PRPTRAE +DV NAVLDG DCVMLSGETA G YP AV Sbjct: 287 KCNLAGKPVICATQMLESMTYNPRPTRAEVSDVGNAVLDGADCVMLSGETAKGNYPINAV 346 Query: 411 QTMAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGG 590 MA+ L AE + Y A + E++A++AV + KA I+VL+ G Sbjct: 347 TIMAETALIAEQAIPYVATYDDLRNFTPKPTSTTETIAAAAVSSVFEQKAKAIIVLSTTG 406 Query: 591 TTARLVAKYRPSMPILSV 644 T RLV+KY+P++PI+ V Sbjct: 407 DTPRLVSKYKPNVPIVMV 424
>KPYK1_CANGA (Q6FIS9) Pyruvate kinase 1 (EC 2.7.1.40) (PK 1)| Length = 501 Score = 202 bits (515), Expect = 6e-52 Identities = 108/198 (54%), Positives = 134/198 (67%) Frame = +3 Query: 51 KVLGEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIF 230 +VLGE K I ++ K+ENQ+GV NFD+IL +DA MVARGDLG+EIP ++ QK +I Sbjct: 227 EVLGEDGKDIKIVVKIENQQGVNNFDEILKVTDAVMVARGDLGIEIPAPEVLAVQKKLIA 286 Query: 231 KCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAV 410 K N+ GKPV+ ATQMLESM +PRPTRAE +DV NAVLDG DCVMLSGETA G YP AV Sbjct: 287 KSNLAGKPVICATQMLESMTYNPRPTRAEVSDVGNAVLDGADCVMLSGETAKGNYPINAV 346 Query: 411 QTMAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGG 590 TMA+ L AE + Y + E++A+SAV KA I+VL+ G Sbjct: 347 TTMAETALIAEQAIAYLPNYDDIRNCTPKPTSTTETVAASAVAAVFEQKAKAIIVLSTSG 406 Query: 591 TTARLVAKYRPSMPILSV 644 TTARLV+KYRP+ PI+ V Sbjct: 407 TTARLVSKYRPNCPIILV 424
>KPYK_SACCA (Q875Z9) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 501 Score = 202 bits (514), Expect = 7e-52 Identities = 106/198 (53%), Positives = 132/198 (66%) Frame = +3 Query: 51 KVLGEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIF 230 +VLGE K I ++ K+ENQ+GV NFD+IL +DA MVARGDLG+EIP ++ QK +I Sbjct: 227 EVLGEDGKDIKIVVKIENQQGVNNFDEILKVTDAVMVARGDLGIEIPAPEVLAVQKKLIA 286 Query: 231 KCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAV 410 K N+ GKPV+ ATQMLESM +PRPTRAE +DV NA+LDG DCVMLSGETA G YP AV Sbjct: 287 KSNLAGKPVICATQMLESMTYNPRPTRAEVSDVGNAILDGADCVMLSGETAKGNYPINAV 346 Query: 411 QTMAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGG 590 TMA L AE + Y ++ E++A+SAV KA I+VL+ G Sbjct: 347 TTMADTALIAEQAIAYQPLYDDLRNLTPKPTSTTETVAASAVAAVYEQKAKAIIVLSTSG 406 Query: 591 TTARLVAKYRPSMPILSV 644 TT RLV+KYRP PI+ V Sbjct: 407 TTPRLVSKYRPDCPIILV 424
>KPYM_MOUSE (P52480) Pyruvate kinase isozyme M2 (EC 2.7.1.40)| Length = 530 Score = 201 bits (512), Expect = 1e-51 Identities = 105/198 (53%), Positives = 134/198 (67%) Frame = +3 Query: 51 KVLGEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIF 230 KVLGE K+I ++SK+EN EGV FD+IL SD MVARGDLG+EIP EK+F AQK+MI Sbjct: 255 KVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIG 314 Query: 231 KCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAV 410 +CN GKPV+ +TQMLE MIK PRPTRAE +DVANAVLDG DC+MLSGETA G YP AV Sbjct: 315 RCNRAGKPVICSTQMLEIMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAV 374 Query: 411 QTMAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGG 590 + I +AE+ + + +F+ E+ A AV + + I+VLT+ G Sbjct: 375 RMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEAAAVGAVEASFKCCSGAIIVLTKSG 434 Query: 591 TTARLVAKYRPSMPILSV 644 +A VA+YRP PI++V Sbjct: 435 RSAHQVARYRPRAPIIAV 452
>KPYK2_CANGA (Q6FV12) Pyruvate kinase 2 (EC 2.7.1.40) (PK 2)| Length = 508 Score = 201 bits (510), Expect = 2e-51 Identities = 105/198 (53%), Positives = 132/198 (66%) Frame = +3 Query: 51 KVLGEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIF 230 +VLGE K I ++ K+ENQ+GV NFD+IL + MVARGDLG+EIP ++ QK +I Sbjct: 227 EVLGEEGKDIKVIVKIENQQGVNNFDEILEVAHGVMVARGDLGIEIPAPQVLAVQKKLIA 286 Query: 231 KCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAV 410 KCN+ GKPV+ ATQMLESM +PRPTRAE +DV NA+LDG DCVMLSGETA G YP AV Sbjct: 287 KCNLAGKPVICATQMLESMTFNPRPTRAEVSDVGNAILDGADCVMLSGETAKGNYPINAV 346 Query: 411 QTMAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGG 590 TMA+ + AE + Y ++ E++A+SAV A LILVL+ G Sbjct: 347 TTMAETAIIAERAIAYMPLYDDLRNCTPKPTSTTETVAASAVAAVQEQGAKLILVLSTSG 406 Query: 591 TTARLVAKYRPSMPILSV 644 TARLV+KYRP PI+ V Sbjct: 407 NTARLVSKYRPQCPIVLV 424
>KPYK_DEBHA (Q6BS75) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 504 Score = 197 bits (502), Expect = 2e-50 Identities = 99/198 (50%), Positives = 131/198 (66%) Frame = +3 Query: 51 KVLGEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIF 230 KVLGE K I +++K+ENQ+GV NFD+IL ++D MVARGDLG+EIP ++F QK +I Sbjct: 230 KVLGEEGKDIQIIAKIENQQGVNNFDEILVETDGVMVARGDLGIEIPAPQVFVVQKQLIA 289 Query: 231 KCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAV 410 KCN+ KPV+ ATQMLESM +PRPTRAE +DV NA+LDG DCVMLSGETA G YP AV Sbjct: 290 KCNLAAKPVICATQMLESMTYNPRPTRAEVSDVGNAILDGADCVMLSGETAKGNYPFEAV 349 Query: 411 QTMAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGG 590 M + AE + Y + E+ A ++V A A I+VL+ G Sbjct: 350 SMMHNTAIIAEKAIAYQPLHNEIRSLANRPTPTTETCAMASVSAAYEQDAKAIVVLSTSG 409 Query: 591 TTARLVAKYRPSMPILSV 644 T+RLV+KY+P++P++ V Sbjct: 410 FTSRLVSKYKPNVPVMMV 427
>KPYK1_YEAST (P00549) Pyruvate kinase 1 (EC 2.7.1.40) (PK 1)| Length = 500 Score = 197 bits (502), Expect = 2e-50 Identities = 103/198 (52%), Positives = 132/198 (66%) Frame = +3 Query: 51 KVLGEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIF 230 +VLGE K + ++ K+ENQ+GV NFD+IL +D MVARGDLG+EIP ++ QK +I Sbjct: 226 EVLGEQGKDVKIIVKIENQQGVNNFDEILKVTDGVMVARGDLGIEIPAPEVLAVQKKLIA 285 Query: 231 KCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAV 410 K N+ GKPV+ ATQMLESM +PRPTRAE +DV NA+LDG DCVMLSGETA G YP AV Sbjct: 286 KSNLAGKPVICATQMLESMTYNPRPTRAEVSDVGNAILDGADCVMLSGETAKGNYPINAV 345 Query: 411 QTMAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGG 590 TMA+ + AE + Y + E++A+SAV KA I+VL+ G Sbjct: 346 TTMAETAVIAEQAIAYLPNYDDMRNCTPKPTSTTETVAASAVAAVFEQKAKAIIVLSTSG 405 Query: 591 TTARLVAKYRPSMPILSV 644 TT RLV+KYRP+ PI+ V Sbjct: 406 TTPRLVSKYRPNCPIILV 423
>KPYR_CANFA (Q29536) Pyruvate kinase isozyme R (EC 2.7.1.40) (Fragment)| Length = 519 Score = 196 bits (499), Expect = 4e-50 Identities = 101/196 (51%), Positives = 133/196 (67%) Frame = +3 Query: 57 LGEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIFKC 236 LG ++I ++SK+EN EGV FD+IL SD MVARGDLG+EIP EK+F AQK+MI +C Sbjct: 246 LGPEGRTIKIISKIENHEGVKKFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRC 305 Query: 237 NIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAVQT 416 N+ GKPVV ATQMLESMI PRPTRAE +DVANAVLDG DC+MLSGETA G +P AV+ Sbjct: 306 NLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGKFPVEAVKM 365 Query: 417 MAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGGTT 596 +I +AE+ V + +F+ E A + V A A I+VLT+ G + Sbjct: 366 QHRIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIATVEAAFKCCAAAIIVLTKTGRS 425 Query: 597 ARLVAKYRPSMPILSV 644 A+L+++YRP +++V Sbjct: 426 AQLLSRYRPRAAVIAV 441
>KPYK_TRIRE (P31865) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 538 Score = 196 bits (498), Expect = 5e-50 Identities = 102/197 (51%), Positives = 134/197 (68%) Frame = +3 Query: 54 VLGEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIFK 233 VLG K I +++K+EN++G+ NF +IL ++D MVARGDLG+EIP ++F AQK MI Sbjct: 250 VLGPEGKQIQIIAKIENRQGLNNFAEILEETDGVMVARGDLGIEIPAAEVFAAQKKMIAM 309 Query: 234 CNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAVQ 413 CNI GKPV+ ATQMLESMIK+PRPTRAE +DV NAV DG DCVMLSGETA G YP ++ Sbjct: 310 CNIAGKPVICATQMLESMIKNPRPTRAEISDVGNAVTDGADCVMLSGETAKGNYPAESIH 369 Query: 414 TMAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGGT 593 M + L+AE+ + Y + F+ +ES A +AVR + A I+VL+ G Sbjct: 370 EMHEASLKAENTIPYVSHFEEMCTLVKRPVSTVESCAMAAVRASLDLGAGGIIVLSTSGD 429 Query: 594 TARLVAKYRPSMPILSV 644 +ARL++KYRP PI V Sbjct: 430 SARLLSKYRPVCPIFMV 446
>KPYK_SCHPO (Q10208) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 509 Score = 195 bits (496), Expect = 9e-50 Identities = 104/199 (52%), Positives = 135/199 (67%), Gaps = 1/199 (0%) Frame = +3 Query: 51 KVLGEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIF 230 +VLGE K+I ++ K+ENQ+GV NFD IL +D MVARGDLG+EIP ++F AQK+MI Sbjct: 233 EVLGEEGKNIKIICKIENQQGVNNFDSILDVTDGIMVARGDLGIEIPASQVFVAQKMMIA 292 Query: 231 KCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAV 410 KCNI GKPV ATQMLESM +PRPTRAE +DV NAVLDG D VMLSGET G+YP AV Sbjct: 293 KCNIAGKPVACATQMLESMTYNPRPTRAEVSDVGNAVLDGADLVMLSGETTKGSYPVEAV 352 Query: 411 QTMAKICLQAESCVDYSAVFKXXXXXXXX-XXXXLESLASSAVRTANSAKATLILVLTRG 587 MA+ AE+ + Y ++++ E+ A +A+ + + A I+VL+ Sbjct: 353 TYMAETARVAEASIPYGSLYQEMFGLVRRPLECATETTAVAAIGASIESDAKAIVVLSTS 412 Query: 588 GTTARLVAKYRPSMPILSV 644 G TARL +KYRPS+PI+ V Sbjct: 413 GNTARLCSKYRPSIPIVMV 431
>KPYK_BACSU (P80885) Pyruvate kinase (EC 2.7.1.40) (PK) (Vegetative protein 17)| (VEG17) Length = 585 Score = 195 bits (495), Expect = 1e-49 Identities = 103/201 (51%), Positives = 135/201 (67%), Gaps = 1/201 (0%) Frame = +3 Query: 51 KVLGEH-AKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMI 227 ++L EH A+ I ++ K+ENQEGV N D IL SD MVARGDLG+EIP E++ QK +I Sbjct: 205 ELLEEHNAQDIQIIPKIENQEGVDNIDAILEVSDGLMVARGDLGVEIPAEEVPLVQKELI 264 Query: 228 FKCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELA 407 KCN GKPV+TATQML+SM ++PRPTRAEA+DVANA+ DGTD +MLSGETAAG+YP A Sbjct: 265 KKCNALGKPVITATQMLDSMQRNPRPTRAEASDVANAIFDGTDAIMLSGETAAGSYPVEA 324 Query: 408 VQTMAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRG 587 VQTM I ++E ++Y + +++ S TA + A I+ T Sbjct: 325 VQTMHNIASRSEEALNYKEILSKRRDQVGMTIT--DAIGQSVAHTAINLNAAAIVTPTES 382 Query: 588 GTTARLVAKYRPSMPILSVVV 650 G TAR++AKYRP PI++V V Sbjct: 383 GHTARMIAKYRPQAPIVAVTV 403
>KPYK_BACPY (P51182) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 586 Score = 194 bits (494), Expect = 2e-49 Identities = 99/198 (50%), Positives = 134/198 (67%) Frame = +3 Query: 66 HAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIFKCNIQ 245 + ++ ++ K+ENQEGV N D+IL SD MVARGDLG+EIP E++ QK +I KCN Sbjct: 211 NGSNLQIIPKIENQEGVDNIDEILNVSDGLMVARGDLGVEIPPEEVPLVQKNLIEKCNQA 270 Query: 246 GKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAVQTMAK 425 GKPV+TATQML+SM ++PRPTRAEA+DVANA+ DGTD +MLSGETAAG YP +VQTM + Sbjct: 271 GKPVITATQMLDSMQRNPRPTRAEASDVANAIFDGTDAIMLSGETAAGIYPVESVQTMDR 330 Query: 426 ICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGGTTARL 605 I L E+ +DY +V E++ +A TA + K +L T G TA++ Sbjct: 331 IALTTEAAIDYRSVVSTRRREKHGNMT--EAIGQAAAYTAINLKVKAVLAPTESGHTAKM 388 Query: 606 VAKYRPSMPILSVVVPEL 659 +AKYRP P+++V E+ Sbjct: 389 IAKYRPGCPVIAVTSSEM 406
>KPYR_HUMAN (P30613) Pyruvate kinase isozymes R/L (EC 2.7.1.40) (R-type/L-type| pyruvate kinase) (Red cell/liver pyruvate kinase) Length = 574 Score = 193 bits (491), Expect = 3e-49 Identities = 102/196 (52%), Positives = 129/196 (65%) Frame = +3 Query: 57 LGEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIFKC 236 LG I ++SK+EN EGV FD+IL SD MVARGDLG+EIP EK+F AQK+MI +C Sbjct: 301 LGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRC 360 Query: 237 NIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAVQT 416 N+ GKPVV ATQMLESMI PRPTRAE +DVANAVLDG DC+MLSGETA G +P AV+ Sbjct: 361 NLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKM 420 Query: 417 MAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGGTT 596 I +AE+ V + +F+ E A AV A A I+VLT G + Sbjct: 421 QHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRS 480 Query: 597 ARLVAKYRPSMPILSV 644 A+L+++YRP +++V Sbjct: 481 AQLLSRYRPRAAVIAV 496
>KPYR_RAT (P12928) Pyruvate kinase isozymes R/L (EC 2.7.1.40) (L-PK)| Length = 574 Score = 192 bits (487), Expect = 1e-48 Identities = 100/196 (51%), Positives = 131/196 (66%) Frame = +3 Query: 57 LGEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIFKC 236 LG ++I ++SK+EN EGV FD+IL SD MVARGDLG+EIP EK+F AQK+MI +C Sbjct: 301 LGPEGQNIKIISKIENHEGVKKFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRC 360 Query: 237 NIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAVQT 416 N+ GKPVV ATQMLESMI RPTRAE +DVANAVLDG DC+MLSGETA G++P AV Sbjct: 361 NLAGKPVVCATQMLESMITKARPTRAETSDVANAVLDGADCIMLSGETAKGSFPVEAVMM 420 Query: 417 MAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGGTT 596 I +AE+ V + +F+ E A AV + A I+VLT+ G + Sbjct: 421 QHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEASFKCCAAAIIVLTKTGRS 480 Query: 597 ARLVAKYRPSMPILSV 644 A+L+++YRP +++V Sbjct: 481 AQLLSQYRPRAAVIAV 496
>KPYR_MOUSE (P53657) Pyruvate kinase isozymes R/L (EC 2.7.1.40) (L-PK)| Length = 574 Score = 191 bits (486), Expect = 1e-48 Identities = 99/196 (50%), Positives = 131/196 (66%) Frame = +3 Query: 57 LGEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIFKC 236 LG + I ++SK+EN EGV FD+IL SD M+ARGDLG+EIP EK+F AQK+MI +C Sbjct: 301 LGPEGRGIKIISKIENHEGVKKFDEILEVSDGIMMARGDLGIEIPAEKVFLAQKMMIGRC 360 Query: 237 NIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAVQT 416 N+ GKPVV ATQMLESMI RPTRAE +DVANAVLDG DC+MLSGETA G++P AV+ Sbjct: 361 NLAGKPVVCATQMLESMITKARPTRAETSDVANAVLDGADCIMLSGETAKGSFPVEAVKM 420 Query: 417 MAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGGTT 596 I +AE+ V + +F+ E A AV + A I+VLT+ G + Sbjct: 421 QHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEASFKCCAAAIIVLTKTGRS 480 Query: 597 ARLVAKYRPSMPILSV 644 A+L+++YRP +++V Sbjct: 481 AQLLSRYRPRAAVIAV 496
>KPYK_CLOAB (O08309) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 473 Score = 190 bits (482), Expect = 4e-48 Identities = 99/203 (48%), Positives = 139/203 (68%), Gaps = 1/203 (0%) Frame = +3 Query: 51 KVLGEHA-KSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMI 227 KVL E+ ++I + SK+ENQEGV N D I+ SD MVARGD+G+EIP++++ QK++I Sbjct: 204 KVLNENGGENIQIFSKIENQEGVDNIDAIIEVSDGIMVARGDMGVEIPIQRVPLIQKMII 263 Query: 228 FKCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELA 407 KCN GKPV+TATQML+SM+++PRPTRAEA+D+ANA+ DGTD +MLSGE+A G+YP A Sbjct: 264 KKCNAVGKPVITATQMLDSMMRNPRPTRAEASDIANAIFDGTDAIMLSGESANGSYPIEA 323 Query: 408 VQTMAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRG 587 V TMAKI +AE+ ++Y + SL + A +A+ I+ T+ Sbjct: 324 VTTMAKIAQEAENEINYDKFLAERKGNEKKNTSDVISLGTCT--AAADLEASAIITATQT 381 Query: 588 GTTARLVAKYRPSMPILSVVVPE 656 G+TAR V+KYRP P+++V E Sbjct: 382 GSTARTVSKYRPKAPVIAVTPSE 404
>KPYK1_SALTI (Q8Z6K2) Pyruvate kinase I (EC 2.7.1.40) (PK-1)| Length = 470 Score = 189 bits (481), Expect = 5e-48 Identities = 106/200 (53%), Positives = 135/200 (67%), Gaps = 4/200 (2%) Frame = +3 Query: 72 KSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIFKCNIQGK 251 ++I ++SK+ENQEG+ NFD+IL SD MVARGDLG+EIPVE++ +AQK+MI KC K Sbjct: 213 ENIQIISKIENQEGLNNFDEILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCIRARK 272 Query: 252 PVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAVQTMAKIC 431 V+TATQML+SMIK+PRPTRAEA DVANA+LDGTD VMLSGE+A G YP AV MA IC Sbjct: 273 VVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVSIMATIC 332 Query: 432 LQAE----SCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGGTTA 599 + + S +DY+ E++ AV TA KA LI+V T+GG +A Sbjct: 333 ERTDRVMNSRLDYN--------NDSRKLRITEAVCRGAVETAEKLKAPLIVVATQGGKSA 384 Query: 600 RLVAKYRPSMPILSVVVPEL 659 R V KY P IL++ E+ Sbjct: 385 RAVRKYFPDATILALTTNEV 404
>KPYK_BACLI (P51181) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 585 Score = 189 bits (480), Expect = 6e-48 Identities = 100/201 (49%), Positives = 132/201 (65%), Gaps = 1/201 (0%) Frame = +3 Query: 51 KVLGEH-AKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMI 227 ++L EH A I ++ K+ENQEGV N D IL SD MVARGDLG+EIP E++ QK +I Sbjct: 205 ELLEEHNAADIQIIPKIENQEGVDNIDAILEVSDGLMVARGDLGVEIPAEEVPLVQKELI 264 Query: 228 FKCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELA 407 KCN GKPV+TATQML+SM ++PRPTRAEA+DVANA+ DGTD +MLSGETAAG YP A Sbjct: 265 KKCNALGKPVITATQMLDSMQRNPRPTRAEASDVANAIFDGTDAIMLSGETAAGNYPVEA 324 Query: 408 VQTMAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRG 587 VQTM I ++E +++ + +++ S TA + I+ T Sbjct: 325 VQTMHNIASRSEEALNHKKILSARSKQVSMSIT--DAIGQSVAHTAINLDVNAIVTPTES 382 Query: 588 GTTARLVAKYRPSMPILSVVV 650 G TAR+++KYRP PI++V V Sbjct: 383 GHTARMISKYRPQAPIVAVTV 403
>KPYK2_YEAST (P52489) Pyruvate kinase 2 (EC 2.7.1.40) (PK 2)| Length = 506 Score = 189 bits (479), Expect = 8e-48 Identities = 98/198 (49%), Positives = 129/198 (65%) Frame = +3 Query: 51 KVLGEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIF 230 K LG + I ++SK+ENQ+G+ NFD+IL +D M+ARGDLG+EI ++ QK +I Sbjct: 228 KALGSEGQDIKIISKIENQQGLDNFDEILEVTDGVMIARGDLGIEILAPEVLAIQKKLIA 287 Query: 231 KCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAV 410 KCN+ GKPV+ ATQML+SM +PRPTRAE +DV NAVLDG DCVMLSGETA G YP AV Sbjct: 288 KCNLAGKPVICATQMLDSMTHNPRPTRAEVSDVGNAVLDGADCVMLSGETAKGDYPVNAV 347 Query: 411 QTMAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGG 590 MA L AES + + A++ E++A++A I+VL+ G Sbjct: 348 NIMAATALIAESTIAHLALYDDLRDATPKPTSTTETVAAAATAAILEQDGKAIVVLSTTG 407 Query: 591 TTARLVAKYRPSMPILSV 644 TARL++KYRPS PI+ V Sbjct: 408 NTARLLSKYRPSCPIILV 425
>KPYK_BACST (Q02499) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 587 Score = 188 bits (478), Expect = 1e-47 Identities = 97/196 (49%), Positives = 132/196 (67%) Frame = +3 Query: 69 AKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIFKCNIQG 248 A I +++K+EN+EGVAN D+IL +D MVARGDLG+EIP E++ QK++I KCN+ G Sbjct: 213 ALHIQIIAKIENEEGVANIDEILEAADGLMVARGDLGVEIPAEEVPLIQKLLIKKCNMLG 272 Query: 249 KPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAVQTMAKI 428 KPV+TATQML+SM ++PRPTRAEA+DVANA+ DGTD VMLSGETAAG YP AV+TM +I Sbjct: 273 KPVITATQMLDSMQRNPRPTRAEASDVANAIFDGTDAVMLSGETAAGQYPVEAVKTMHQI 332 Query: 429 CLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGGTTARLV 608 L+ E +++ + +++ S TA + I+ T G T ++V Sbjct: 333 ALRTEQALEHRDILSQRTKESQTTIT--DAIGQSVAHTALNLDVAAIVTPTVSGKTPQMV 390 Query: 609 AKYRPSMPILSVVVPE 656 AKYRP PI++V E Sbjct: 391 AKYRPKAPIIAVTSNE 406
>KPYK1_SALTY (P77983) Pyruvate kinase I (EC 2.7.1.40) (PK-1)| Length = 470 Score = 188 bits (477), Expect = 1e-47 Identities = 105/200 (52%), Positives = 135/200 (67%), Gaps = 4/200 (2%) Frame = +3 Query: 72 KSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIFKCNIQGK 251 ++I ++SK+ENQEG+ NFD+IL SD MVARGDLG+EIPVE++ +AQK+MI KC K Sbjct: 213 ENIQIISKIENQEGLNNFDEILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCIRARK 272 Query: 252 PVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAVQTMAKIC 431 V+TATQML+SMIK+PRPTRAEA DVANA+LDGTD VMLSGE+A G YP AV MA IC Sbjct: 273 VVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVSIMATIC 332 Query: 432 LQAE----SCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGGTTA 599 + + S +DY+ E++ AV TA +A LI+V T+GG +A Sbjct: 333 ERTDRVMNSRLDYN--------NDSRKLRITEAVCRGAVETAEKLEAPLIVVATQGGKSA 384 Query: 600 RLVAKYRPSMPILSVVVPEL 659 R V KY P IL++ E+ Sbjct: 385 RAVRKYFPDATILALTTNEV 404
>KPYK1_ECOLI (P0AD61) Pyruvate kinase I (EC 2.7.1.40) (PK-1)| Length = 470 Score = 187 bits (475), Expect = 2e-47 Identities = 103/195 (52%), Positives = 131/195 (67%) Frame = +3 Query: 72 KSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIFKCNIQGK 251 ++I ++SK+ENQEG+ NFD+IL SD MVARGDLG+EIPVE++ +AQK+MI KC K Sbjct: 213 ENIHIISKIENQEGLNNFDEILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCIRARK 272 Query: 252 PVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAVQTMAKIC 431 V+TATQML+SMIK+PRPTRAEA DVANA+LDGTD VMLSGE+A G YP AV MA IC Sbjct: 273 VVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVSIMATIC 332 Query: 432 LQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGGTTARLVA 611 + + ++ F E++ AV TA A LI+V T+GG +AR V Sbjct: 333 ERTDRVMNSRLEFNNDNRKLRIT----EAVCRGAVETAEKLDAPLIVVATQGGKSARAVR 388 Query: 612 KYRPSMPILSVVVPE 656 KY P IL++ E Sbjct: 389 KYFPDATILALTTNE 403
>KPYK1_ECO57 (P0AD62) Pyruvate kinase I (EC 2.7.1.40) (PK-1)| Length = 470 Score = 187 bits (475), Expect = 2e-47 Identities = 103/195 (52%), Positives = 131/195 (67%) Frame = +3 Query: 72 KSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIFKCNIQGK 251 ++I ++SK+ENQEG+ NFD+IL SD MVARGDLG+EIPVE++ +AQK+MI KC K Sbjct: 213 ENIHIISKIENQEGLNNFDEILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCIRARK 272 Query: 252 PVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAVQTMAKIC 431 V+TATQML+SMIK+PRPTRAEA DVANA+LDGTD VMLSGE+A G YP AV MA IC Sbjct: 273 VVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVSIMATIC 332 Query: 432 LQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGGTTARLVA 611 + + ++ F E++ AV TA A LI+V T+GG +AR V Sbjct: 333 ERTDRVMNSRLEFNNDNRKLRIT----EAVCRGAVETAEKLDAPLIVVATQGGKSARAVR 388 Query: 612 KYRPSMPILSVVVPE 656 KY P IL++ E Sbjct: 389 KYFPDATILALTTNE 403
>KPYK_CLOPE (Q46289) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 474 Score = 182 bits (461), Expect = 1e-45 Identities = 90/199 (45%), Positives = 140/199 (70%), Gaps = 1/199 (0%) Frame = +3 Query: 51 KVLGEHA-KSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMI 227 ++L H K I ++SK+E+QEGV N +I+ +D MVARGD+G+EIP+E + QK +I Sbjct: 204 EILDSHGGKDIKIISKIESQEGVDNIKEIIKVTDGVMVARGDMGVEIPIENVPIIQKNII 263 Query: 228 FKCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELA 407 KCN GK V+TATQML+SMI++PRPTRAEA+DV NA+ DGTD +MLSGE+A+G++P A Sbjct: 264 KKCNQAGKIVITATQMLDSMIRNPRPTRAEASDVCNAIFDGTDAIMLSGESASGSFPIEA 323 Query: 408 VQTMAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRG 587 TM++I +AE+ +DY+ + + ++++ SA +TA+ I+ T+ Sbjct: 324 AMTMSRIAKKAEANLDYNYLLRRLKDPNPNPDAFADAISYSASKTASKFPTKAIVAATQT 383 Query: 588 GTTARLVAKYRPSMPILSV 644 G+TA++++KY+PS PI+++ Sbjct: 384 GSTAKILSKYKPSCPIIAI 402
>KPYK_LACDE (P34038) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 589 Score = 176 bits (447), Expect = 4e-44 Identities = 92/197 (46%), Positives = 122/197 (61%) Frame = +3 Query: 66 HAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIFKCNIQ 245 +A + + K+E+QEG+ N D+IL SD MVARGD+G+EIP + + QK +I KCN Sbjct: 212 NASYVKIFPKIESQEGIDNIDEILQVSDGLMVARGDMGVEIPFINVPFVQKTLIKKCNAL 271 Query: 246 GKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAVQTMAK 425 GKPV+TATQML+SM ++PRPTRAE TDVANAVLDGTD MLSGE+A G YP +VQ M Sbjct: 272 GKPVITATQMLDSMQENPRPTRAEVTDVANAVLDGTDATMLSGESANGLYPVQSVQAMHD 331 Query: 426 ICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGGTTARL 605 I ++ E +D E++ S VRTA I+ T G TAR+ Sbjct: 332 IDVRTEKELDTRNTLALQRFEEYKGSNVTEAIGESVVRTAQELGVKTIIAATSSGYTARM 391 Query: 606 VAKYRPSMPILSVVVPE 656 ++KYRP I+++ E Sbjct: 392 ISKYRPDATIVALTFDE 408
>KPYK_TRYBO (Q27788) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 498 Score = 175 bits (443), Expect = 1e-43 Identities = 91/187 (48%), Positives = 122/187 (65%) Frame = +3 Query: 78 IMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIFKCNIQGKPV 257 I +++K+EN +G+ N D I+ +D MVARGDLG+EIP EK+ AQK+++ KCN GK V Sbjct: 233 IAVIAKIENYQGIDNIDAIIDAADGIMVARGDLGVEIPAEKVVIAQKMIMSKCNKVGKTV 292 Query: 258 VTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAVQTMAKICLQ 437 + ATQML+SM PRPTRAE +DVA +VLDG DCVMLSGETA G YP V M++IC + Sbjct: 293 ICATQMLDSMTHGPRPTRAEVSDVAKSVLDGADCVMLSGETAKGKYPVETVVYMSRICCE 352 Query: 438 AESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGGTTARLVAKY 617 + + A F+ E++ SSAV + A ILVLT G +A +V+KY Sbjct: 353 TQVTMWNMAAFEAIKNLQSFPLIPEEAICSSAVNSIFELHAKAILVLTNTGRSAHMVSKY 412 Query: 618 RPSMPIL 638 RP +PI+ Sbjct: 413 RPPVPII 419
>KPYK1_PHOLE (O30853) Pyruvate kinase I (EC 2.7.1.40) (PK-1) (Fragment)| Length = 235 Score = 159 bits (403), Expect = 5e-39 Identities = 89/167 (53%), Positives = 110/167 (65%) Frame = +3 Query: 144 SDAFMVARGDLGMEIPVEKIFYAQKVMIFKCNIQGKPVVTATQMLESMIKSPRPTRAEAT 323 SD MVARGDLG+EIPVE++ +AQK+MI KCN K V+TATQML+SMIK+PRPTRAEA Sbjct: 2 SDGIMVARGDLGVEIPVEEVIFAQKMMIEKCNRARKVVITATQMLDSMIKNPRPTRAEAG 61 Query: 324 DVANAVLDGTDCVMLSGETAAGAYPELAVQTMAKICLQAESCVDYSAVFKXXXXXXXXXX 503 DVANA++DGTD VMLSGE+A G YP AV MA+IC + + V + Sbjct: 62 DVANAIMDGTDAVMLSGESAKGKYPIEAVTIMAQICARTDDVVKP----ELGSRLDSPRL 117 Query: 504 XXLESLASSAVRTANSAKATLILVLTRGGTTARLVAKYRPSMPILSV 644 E++ AV TA A LI+V T G +AR V KY P+ IL+V Sbjct: 118 RITEAVCKGAVDTAEKLNAPLIIVATEAGKSARSVRKYFPTARILAV 164
>KPYK_CHLMU (Q9PK61) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 481 Score = 158 bits (399), Expect = 2e-38 Identities = 91/215 (42%), Positives = 129/215 (60%), Gaps = 2/215 (0%) Frame = +3 Query: 6 FVVCSQGFXILWRSGKVLGEHAKSIM-LMSKVENQEGVANFDDILAQSDAFMVARGDLGM 182 FV C++ + KVL + M +++K+EN GV NF +I SD M+ARGDLG+ Sbjct: 192 FVRCNEDIDSM---RKVLENFGRPNMPIIAKIENHLGVQNFQEIAKASDGIMIARGDLGI 248 Query: 183 EIPVEKIFYAQKVMIFKCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCV 362 E+ + ++ QK M G+ +TATQMLESMI++P PTRAE +DVANA+ DGT V Sbjct: 249 ELSIVEVPALQKFMARVSRETGRFCITATQMLESMIRNPLPTRAEVSDVANAIHDGTSAV 308 Query: 363 MLSGETAAGAYPELAVQTMAKICLQAESCVDYSAVFKXXXXXXXXXXX-XLESLASSAVR 539 MLSGETA+G YP AV+TM I + E DY A F+ LE++ +S ++ Sbjct: 309 MLSGETASGTYPIEAVKTMRSIIQETEKSFDYQAFFQLNDKNSALKVSPYLEAIGASGIQ 368 Query: 540 TANSAKATLILVLTRGGTTARLVAKYRPSMPILSV 644 A A A I+V T+ G + ++KYRP +PI++V Sbjct: 369 IAEKASAKAIIVYTQTGGSPMFLSKYRPYLPIIAV 403
>KPYK_LACLA (Q07637) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 502 Score = 157 bits (398), Expect = 2e-38 Identities = 84/194 (43%), Positives = 123/194 (63%), Gaps = 1/194 (0%) Frame = +3 Query: 78 IMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIFKCNIQGKPV 257 + L++K+ENQ+G+ N D+I+ +D M+ARGD+G+E+P E + QK++I K N GK V Sbjct: 245 VQLLAKIENQQGIENLDEIIEAADGIMIARGDMGIEVPFEMVPVYQKLIISKVNKAGKIV 304 Query: 258 VTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAVQTMAKICLQ 437 VTAT MLESM +PR TR+E +DV NAV+DGTD MLSGE+A G YP +V+TMA + Sbjct: 305 VTATNMLESMTYNPRATRSEISDVFNAVIDGTDATMLSGESANGKYPRESVRTMATVNKN 364 Query: 438 AESCV-DYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGGTTARLVAK 614 A++ + +Y + E +A+S A + LI+ LT G TARL++K Sbjct: 365 AQTMLKEYGRLHPERYDKSTVT----EVVAASVKNAAEAMDIKLIVALTESGNTARLISK 420 Query: 615 YRPSMPILSVVVPE 656 +RP+ IL++ E Sbjct: 421 HRPNADILAITFDE 434
>KPYK_CHLTR (P94685) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 485 Score = 155 bits (392), Expect = 1e-37 Identities = 90/215 (41%), Positives = 128/215 (59%), Gaps = 2/215 (0%) Frame = +3 Query: 6 FVVCSQGFXILWRSGKVLGEHAKSIM-LMSKVENQEGVANFDDILAQSDAFMVARGDLGM 182 FV C++ + KVL + M +++K+EN GV NF +I +D M+ARGDLG+ Sbjct: 192 FVRCNEDIDSM---RKVLESFGRPNMPIIAKIENHLGVQNFQEIARAADGIMIARGDLGI 248 Query: 183 EIPVEKIFYAQKVMIFKCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCV 362 E+ + ++ QK M G+ +TATQMLESMI++P PTRAE +DVANA+ DGT V Sbjct: 249 ELSIVEVPGLQKFMARASRETGRFCITATQMLESMIRNPLPTRAEVSDVANAIYDGTSAV 308 Query: 363 MLSGETAAGAYPELAVQTMAKICLQAESCVDYSAVFKXXXXXXXXXXX-XLESLASSAVR 539 MLSGETA GA+P AV+TM I + E DY A F+ LE++ S ++ Sbjct: 309 MLSGETALGAHPVHAVKTMRSIIQETEKTFDYHAFFQLNDKNSALKVSPYLEAIGFSGIQ 368 Query: 540 TANSAKATLILVLTRGGTTARLVAKYRPSMPILSV 644 A A A I+V T+ G + ++KYRP +PI++V Sbjct: 369 IAEKASAKAIIVYTQTGGSPMFLSKYRPYLPIIAV 403
>KPYK2_SYNY3 (P73534) Pyruvate kinase 2 (EC 2.7.1.40) (PK 2)| Length = 591 Score = 154 bits (390), Expect = 2e-37 Identities = 86/191 (45%), Positives = 119/191 (62%) Frame = +3 Query: 72 KSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIFKCNIQGK 251 KS+ +++K+E E + + +L + D MVARGDLG+E+P E + QK +I N G Sbjct: 220 KSVPVIAKIEKHEAIKDMQAVLEKCDGVMVARGDLGVELPAEDVPILQKKLIATANRLGI 279 Query: 252 PVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAVQTMAKIC 431 PV+TATQML+SM+ SPRPTRAE +DVANA+LDGTD VMLS ETA G +P AV MAKI Sbjct: 280 PVITATQMLDSMVNSPRPTRAEVSDVANAILDGTDAVMLSNETAIGKFPVEAVAIMAKIA 339 Query: 432 LQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGGTTARLVA 611 + E D + +++S+ + A + A I+ LT+ G+TAR V+ Sbjct: 340 ERIEQ-EDINP-----SQAEASRTSIPNAISSAVSQIAETLNAAAIMSLTKTGSTARHVS 393 Query: 612 KYRPSMPILSV 644 K+RP PIL+V Sbjct: 394 KFRPKTPILAV 404
>KPYK1_AGRVI (P70789) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 474 Score = 150 bits (379), Expect = 3e-36 Identities = 83/191 (43%), Positives = 117/191 (61%) Frame = +3 Query: 84 LMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIFKCNIQGKPVVT 263 L++K+E + DDI+A SDA MVARGDLG+EIP E + QK +I C I KPV+ Sbjct: 217 LIAKIEKPSALDEIDDIVALSDAIMVARGDLGVEIPPEDVPGRQKELIRACRIAAKPVIV 276 Query: 264 ATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAVQTMAKICLQAE 443 ATQML+SM+ SP PTRAEA+DVA A+ DG D VMLS E+A GA+P V+ M++I + E Sbjct: 277 ATQMLDSMVTSPTPTRAEASDVAGAIYDGADAVMLSAESATGAFPVETVEIMSRIIEKTE 336 Query: 444 SCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGGTTARLVAKYRP 623 Y + + ++A++A A + KA +I+ T GTTA +++ RP Sbjct: 337 KHKFYRPILEATEPQIAHTPP--HAVATAAADVALALKAPVIVAFTVSGTTASRISRARP 394 Query: 624 SMPILSVVVPE 656 +PIL++ E Sbjct: 395 PLPILALTPSE 405
>KPYK2_AGRVI (Q44473) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 482 Score = 147 bits (370), Expect = 4e-35 Identities = 79/191 (41%), Positives = 117/191 (61%) Frame = +3 Query: 84 LMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIFKCNIQGKPVVT 263 L++K+E + + +DI+ SD+ MVARGDLG+EIP E + QK +I C + KPV+ Sbjct: 217 LIAKIEKPSALDDIEDIVRLSDSVMVARGDLGVEIPPEDVPGKQKEIIRACRLAAKPVIV 276 Query: 264 ATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAVQTMAKICLQAE 443 ATQML+SM+ SP PTRAEA+DVA A+ DG D VMLS ETA GAYP AV+ M +I + E Sbjct: 277 ATQMLDSMVSSPTPTRAEASDVAGAIYDGADAVMLSAETATGAYPVEAVEIMNRIIEKTE 336 Query: 444 SCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGGTTARLVAKYRP 623 Y + + ++A++A A + + +++ T GTTA +++ RP Sbjct: 337 KHKHYRPILEATEPDVAQSPP--HAVATAAANVAVALGSPVVVAYTSSGTTAARISRARP 394 Query: 624 SMPILSVVVPE 656 ++PIL++ E Sbjct: 395 ALPILALTPSE 405
>KPYK_CHLPN (Q9Z984) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 484 Score = 141 bits (355), Expect = 2e-33 Identities = 75/188 (39%), Positives = 114/188 (60%), Gaps = 1/188 (0%) Frame = +3 Query: 84 LMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIFKCNIQGKPVVT 263 +++K+EN+ GV NF I +D M+ARGDLG+E+ V ++ QK+M G VT Sbjct: 216 IIAKIENRLGVENFSKIAKLADGIMIARGDLGIELSVVEVPNLQKMMAKVSRETGHFCVT 275 Query: 264 ATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAVQTMAKICLQAE 443 ATQMLESMI++ PTRAE +D+ANA+ DG+ VMLSGETA+GA+P AV+ M + L+ E Sbjct: 276 ATQMLESMIRNVLPTRAEVSDIANAIYDGSSAVMLSGETASGAHPVAAVKIMRSVILETE 335 Query: 444 SCVDYSAVFKXXXXXXXXXXX-XLESLASSAVRTANSAKATLILVLTRGGTTARLVAKYR 620 + + + K L ++ + ++ A A A ++V T G++ ++KYR Sbjct: 336 KNLSHDSFLKLDDSNSALQVSPYLSAIGLAGIQIAERADAKALIVYTESGSSPMFLSKYR 395 Query: 621 PSMPILSV 644 P PI++V Sbjct: 396 PKFPIIAV 403
>KPYK1_SYNY3 (Q55863) Pyruvate kinase 1 (EC 2.7.1.40) (PK 1)| Length = 483 Score = 140 bits (354), Expect = 3e-33 Identities = 78/191 (40%), Positives = 115/191 (60%) Frame = +3 Query: 84 LMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIFKCNIQGKPVVT 263 +++K+E + + N ++I+A S+ MVARGDLG+E+ EK+ QK +I +CN++ PV+T Sbjct: 230 VIAKIEKPQAIDNLEEIVAVSNGIMVARGDLGVEVNPEKVPRLQKEIIRRCNVRAIPVIT 289 Query: 264 ATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAVQTMAKICLQAE 443 ATQML+SMI++ RPTRAEA+DVANA+LDGTD VMLSGE+A G YP +VQ + KI + E Sbjct: 290 ATQMLDSMIQNSRPTRAEASDVANAILDGTDAVMLSGESAVGQYPVKSVQMLRKIAEETE 349 Query: 444 SCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGGTTARLVAKYRP 623 V +L+ + V I+ T G T+ L + RP Sbjct: 350 -------VGLHLVNNPPIENTETHALSEALVVIDGILDLKYIVTFTTSGFTSLLASNQRP 402 Query: 624 SMPILSVVVPE 656 S+P+++ E Sbjct: 403 SVPVIAFTPSE 413
>KPYK2_SALTY (Q8ZNW0) Pyruvate kinase II (EC 2.7.1.40) (PK-2)| Length = 479 Score = 140 bits (352), Expect = 4e-33 Identities = 89/217 (41%), Positives = 120/217 (55%), Gaps = 4/217 (1%) Frame = +3 Query: 6 FVVCSQGFXILWRSGKVLGEHAKSIMLMSKVENQEGVAN---FDDILAQSDAFMVARGDL 176 F C + R + G AK +++KVE E V + DDI+ SD MVARGDL Sbjct: 196 FPRCGEDLNYARRLARDAGCDAK---IVAKVERAEAVCDQNAMDDIILASDVVMVARGDL 252 Query: 177 GMEIPVEKIFYAQKVMIFKCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTD 356 G+EI ++ QK +I + + V+TATQM+ESMI +P PTRAE DVANAVLDGTD Sbjct: 253 GVEIGDPELVGIQKALIRRARQLNRAVITATQMMESMITNPMPTRAEVMDVANAVLDGTD 312 Query: 357 CVMLSGETAAGAYPELAVQTMAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAV 536 VMLS ETAAG YP V MA++CL AE ++ E++A SA+ Sbjct: 313 AVMLSAETAAGQYPSETVAAMARVCLGAEK---IPSINVSKHRLDVQFDNVEEAIAMSAM 369 Query: 537 RTANSAK-ATLILVLTRGGTTARLVAKYRPSMPILSV 644 AN K T I+ +T G TA + ++ +PI ++ Sbjct: 370 YAANHLKGVTAIITMTESGRTALMTSRISSGLPIFAM 406
>KPYK2_ECOLI (P21599) Pyruvate kinase II (EC 2.7.1.40) (PK-2)| Length = 479 Score = 140 bits (352), Expect = 4e-33 Identities = 89/217 (41%), Positives = 120/217 (55%), Gaps = 4/217 (1%) Frame = +3 Query: 6 FVVCSQGFXILWRSGKVLGEHAKSIMLMSKVENQEGVAN---FDDILAQSDAFMVARGDL 176 F C + R + G AK +++KVE E V + DDI+ SD MVARGDL Sbjct: 196 FPRCGEDLNYARRLARDAGCDAK---IVAKVERAEAVCSQDAMDDIILASDVVMVARGDL 252 Query: 177 GMEIPVEKIFYAQKVMIFKCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTD 356 G+EI ++ QK +I + + V+TATQM+ESMI +P PTRAE DVANAVLDGTD Sbjct: 253 GVEIGDPELVGIQKALIRRARQLNRAVITATQMMESMITNPMPTRAEVMDVANAVLDGTD 312 Query: 357 CVMLSGETAAGAYPELAVQTMAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAV 536 VMLS ETAAG YP V MA++CL AE ++ E++A SA+ Sbjct: 313 AVMLSAETAAGQYPSETVAAMARVCLGAEK---IPSINVSKHRLDVQFDNVEEAIAMSAM 369 Query: 537 RTANSAK-ATLILVLTRGGTTARLVAKYRPSMPILSV 644 AN K T I+ +T G TA + ++ +PI ++ Sbjct: 370 YAANHLKGVTAIITMTESGRTALMTSRISSGLPIFAM 406
>KPYK_BORBU (O51323) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 477 Score = 139 bits (349), Expect = 1e-32 Identities = 77/186 (41%), Positives = 109/186 (58%) Frame = +3 Query: 78 IMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIFKCNIQGKPV 257 + ++SK+ENQEG+ N ++I S MVARGD+G+EIP E + AQ + C G PV Sbjct: 209 VKIISKIENQEGIDNIEEIAKASYGIMVARGDMGVEIPAEDVPIAQLKITQTCIKYGIPV 268 Query: 258 VTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAVQTMAKICLQ 437 +TATQML +MI++PRPTRAE +D+ANA+L+GTD +MLSGETA G YP AV+ M I + Sbjct: 269 ITATQMLHTMIENPRPTRAEVSDIANAILNGTDAIMLSGETAYGKYPIEAVKMMTSIAKK 328 Query: 438 AESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGGTTARLVAKY 617 E + + + A+ I+V + G TAR++A Y Sbjct: 329 VEK---HRKMTLYKDELFYDKSITRNYIIKCAIDATKLMDIKAIIVDSLKGKTARIMATY 385 Query: 618 RPSMPI 635 R S+P+ Sbjct: 386 RASVPL 391
>KPYK_HAEIN (P43924) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 477 Score = 137 bits (345), Expect = 3e-32 Identities = 85/191 (44%), Positives = 111/191 (58%), Gaps = 4/191 (2%) Frame = +3 Query: 84 LMSKVENQEGVAN---FDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIFKCNIQGKP 254 +++KVE E VAN DDI+ SD MVARGDLG+EI ++ QK +I + + Sbjct: 219 IVAKVERAETVANDEAMDDIILASDVIMVARGDLGVEIGDPELVGVQKKLIRRSRQLNRA 278 Query: 255 VVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAVQTMAKICL 434 V+TATQM+ESMI +P PTRAE DVANAVLDGTD VMLS ETAAG YP V MA +CL Sbjct: 279 VITATQMMESMISNPMPTRAEVMDVANAVLDGTDAVMLSAETAAGQYPSETVAAMASVCL 338 Query: 435 QAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAK-ATLILVLTRGGTTARLVA 611 AE ++ ES+A SA+ AN K I+ L+ G T L++ Sbjct: 339 GAEK---MPSINVSRHRMDKEFETIEESVAMSAMYAANHMKGVAAIVTLSSTGRTPLLMS 395 Query: 612 KYRPSMPILSV 644 + +PI ++ Sbjct: 396 RISSGLPIFAL 406
>KPYK_BUCAI (P57404) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 480 Score = 136 bits (343), Expect = 5e-32 Identities = 88/217 (40%), Positives = 120/217 (55%), Gaps = 4/217 (1%) Frame = +3 Query: 6 FVVCSQGFXILWRSGKVLGEHAKSIMLMSKVENQEGVAN---FDDILAQSDAFMVARGDL 176 F CS + K G +AK +++K+E E V N +DI+ SDA M+ARGDL Sbjct: 197 FPRCSNDLKQARKLAKEFGSNAK---IIAKIERAEAVLNQNTIEDIILASDAIMIARGDL 253 Query: 177 GMEIPVEKIFYAQKVMIFKCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTD 356 G+EI ++ QK +I + V+TATQM+ESMI +P PTRAE DVANAVLDG+D Sbjct: 254 GVEIGDSELAGIQKKLIRTARQLNRIVITATQMMESMITNPLPTRAEVMDVANAVLDGSD 313 Query: 357 CVMLSGETAAGAYPELAVQTMAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAV 536 VMLS ETA+G YP V MAKIC AE ++ E++A SA+ Sbjct: 314 AVMLSAETASGEYPAETVIKMAKICKGAEK---VPSINVSRHRIHAKFDDIEEAIAMSAM 370 Query: 537 RTANSAKA-TLILVLTRGGTTARLVAKYRPSMPILSV 644 AN K T I+ +T G TA + ++ +PI ++ Sbjct: 371 YVANHLKGITAIITMTESGKTALMTSRITSGLPIFAL 407
>KPYK_MYCIT (P94939) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 472 Score = 134 bits (337), Expect = 2e-31 Identities = 78/197 (39%), Positives = 116/197 (58%) Frame = +3 Query: 51 KVLGEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIF 230 +V+ + + +++K+E E V N + I+ DA MVARGDLG+E+P+E++ QK I Sbjct: 204 EVMDRVGRRVPVIAKLEKPEAVDNLETIVLAFDAIMVARGDLGVELPLEEVPLVQKRAIQ 263 Query: 231 KCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAV 410 KPV+ ATQML+SMI++ RPTRAEA+DVANAVLDG D VMLSGET+ G YP AV Sbjct: 264 MARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADAVMLSGETSVGKYPMAAV 323 Query: 411 QTMAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGG 590 +TM++I E ++ + S A+ + AKA ++ T+ G Sbjct: 324 RTMSRIICAVED----NSTAAPPLTHVPRTKRGVISYAARDIGERLDAKA--LVAFTQSG 377 Query: 591 TTARLVAKYRPSMPILS 641 T + +A+ +P+L+ Sbjct: 378 DTVKRLARLHTPLPLLA 394
>KPYK_CORGL (Q46078) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 475 Score = 133 bits (335), Expect = 4e-31 Identities = 79/199 (39%), Positives = 116/199 (58%), Gaps = 3/199 (1%) Frame = +3 Query: 51 KVLGEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIF 230 K++ E + + +++K+E E V + + I+ DA MVARGDLG+E+P+E++ QK I Sbjct: 204 KIMDEEGRRVPVIAKLEKPEAVTSLEPIVLAFDAVMVARGDLGVEVPLEEVPLVQKRAIQ 263 Query: 231 KCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAV 410 KPV+ ATQML+SMI++ RPTRAEA+DVANAVLDG D VMLSGET+ G P V Sbjct: 264 IARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADAVMLSGETSVGKDPHNVV 323 Query: 411 QTMAKICLQAES---CVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLT 581 +TM++I AE+ D + + + ++ SA A A ++ T Sbjct: 324 RTMSRIVRFAETDGRVPDLTHIPRTKRGV----------ISYSARDIAERLNARALVAFT 373 Query: 582 RGGTTARLVAKYRPSMPIL 638 G TA+ VA+ +P+L Sbjct: 374 TSGDTAKRVARLHSHLPLL 392
>KPYK_BUCBP (Q89AI8) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 479 Score = 133 bits (334), Expect = 5e-31 Identities = 77/196 (39%), Positives = 113/196 (57%), Gaps = 1/196 (0%) Frame = +3 Query: 60 GEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIFKCN 239 G AK I + + E + + D+I+ SDA MVARGDLG+EI ++ QK +I + Sbjct: 215 GSKAKIIAKIERAEAVKDLKIIDEIILASDAIMVARGDLGVEIGESELAGIQKTLIRRAR 274 Query: 240 IQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAVQTM 419 + V+TATQM+ESMI +P PTRAE DVANAVLDG+D VMLS ETA+G YP ++ M Sbjct: 275 QLNRVVITATQMMESMINNPMPTRAEVMDVANAVLDGSDAVMLSAETASGKYPIETIKVM 334 Query: 420 AKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKA-TLILVLTRGGTT 596 +K+C+ AE ++ E++A SA+ AN T I+ +T G T Sbjct: 335 SKVCMGAEK---MPSINVSQHRIHDKFHDIEEAIAMSAMYAANHLSGITAIITMTESGKT 391 Query: 597 ARLVAKYRPSMPILSV 644 + + ++ +PI ++ Sbjct: 392 SLMTSRITSGLPIFAL 407
>KPYK_MYCTU (O06134) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 472 Score = 132 bits (333), Expect = 7e-31 Identities = 77/197 (39%), Positives = 117/197 (59%) Frame = +3 Query: 51 KVLGEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIF 230 +V+ + + +++K+E E + N + I+ DA MVARGDLG+E+P+E++ QK I Sbjct: 204 EVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQ 263 Query: 231 KCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAV 410 KPV+ ATQML+SMI++ RPTRAEA+DVANAVLDG D +MLSGET+ G YP AV Sbjct: 264 MARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSVGKYPLAAV 323 Query: 411 QTMAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGG 590 +TM++I V+ ++ + S A+ + AKA ++ T+ G Sbjct: 324 RTMSRII----CAVEENSTAAPPLTHIPRTKRGVISYAARDIGERLDAKA--LVAFTQSG 377 Query: 591 TTARLVAKYRPSMPILS 641 T R +A+ +P+L+ Sbjct: 378 DTVRRLARLHTPLPLLA 394
>KPYG_RICCO (P55964) Pyruvate kinase isozyme G, chloroplast (EC 2.7.1.40)| (Fragment) Length = 418 Score = 132 bits (331), Expect = 1e-30 Identities = 79/188 (42%), Positives = 110/188 (58%) Frame = +3 Query: 78 IMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIFKCNIQGKPV 257 I ++ K+E+ + + N I++ SD MVARGDLG E+P+E++ Q+ +I +C+ KPV Sbjct: 158 IHVIVKIESADSIPNLHSIISASDGAMVARGDLGAELPIEEVPLLQEDIIRRCHSMQKPV 217 Query: 258 VTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAVQTMAKICLQ 437 + AT MLESMI P PTRAE +D+A AV +G D VMLSGETA G YP AV+ M + L+ Sbjct: 218 IVATNMLESMINHPTPTRAEVSDIAIAVREGADAVMLSGETAHGKYPLKAVRVMHTVALR 277 Query: 438 AESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGGTTARLVAKY 617 ES S V E A A AN+ T I+V TR G+ A L++ Y Sbjct: 278 TESS---SPVNTTPPAQGAYKGHMGEMFAFHATIMANTLN-TPIIVFTRTGSMAVLLSHY 333 Query: 618 RPSMPILS 641 +P+ I + Sbjct: 334 QPASTIFA 341
>KPYK_COREF (Q8FP04) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 474 Score = 131 bits (330), Expect = 2e-30 Identities = 78/198 (39%), Positives = 115/198 (58%), Gaps = 3/198 (1%) Frame = +3 Query: 54 VLGEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIFK 233 ++ E + + +++K+E E VA + I+ DA MVARGDLG+E+P+E++ QK I Sbjct: 205 IMDEEGRRVPVIAKLEKPEAVAALESIVLAFDAIMVARGDLGVEVPLEEVPLVQKRAIQI 264 Query: 234 CNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAVQ 413 KPV+ ATQML+SMI++ RPTRAEA+DVANAVLDG D VMLSGET+ G P V+ Sbjct: 265 ARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADAVMLSGETSVGKDPHNVVR 324 Query: 414 TMAKICLQAES---CVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTR 584 TM++I AE+ D + + + ++ SA A A ++ T Sbjct: 325 TMSRIVRFAETDGRVPDLTHIPRTKRGV----------ISYSARDIAERLNARALVAFTT 374 Query: 585 GGTTARLVAKYRPSMPIL 638 G TA+ +A+ +P+L Sbjct: 375 SGDTAKRLARLHSHLPLL 392
>KPYK_BUCAP (Q8K9M3) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 481 Score = 130 bits (327), Expect = 3e-30 Identities = 79/207 (38%), Positives = 119/207 (57%), Gaps = 4/207 (1%) Frame = +3 Query: 36 LWRSGKVLGEHAKSIMLMSKVENQEGVAN---FDDILAQSDAFMVARGDLGMEIPVEKIF 206 L ++ ++L + + +++K+E E V + ++I+ SDA M+ARGDLG+EI ++ Sbjct: 204 LIKARELLKKSGSNAQIIAKIERAEAVFDQNAIENIILSSDAIMIARGDLGVEIGDAELV 263 Query: 207 YAQKVMIFKCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAA 386 QK +I K +TATQM+ESMI +P PTRAE DVANAVLDG+D VMLS ETA+ Sbjct: 264 GIQKKLIRTARKLNKVAITATQMMESMILNPLPTRAEVMDVANAVLDGSDAVMLSAETAS 323 Query: 387 GAYPELAVQTMAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKA-T 563 G YP V +MAK+C AE ++ E++A S++ AN K T Sbjct: 324 GKYPSETVISMAKVCKGAEK---VPSINVSRHRLNVEFQSIEEAIAMSSMYAANHLKGIT 380 Query: 564 LILVLTRGGTTARLVAKYRPSMPILSV 644 I+ +T G TA + ++ +PI ++ Sbjct: 381 AIITMTESGKTALMTSRITSGLPIFAL 407
>KPYG_TOBAC (Q40546) Pyruvate kinase isozyme G, chloroplast precursor (EC| 2.7.1.40) Length = 562 Score = 130 bits (327), Expect = 3e-30 Identities = 75/188 (39%), Positives = 112/188 (59%) Frame = +3 Query: 78 IMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIFKCNIQGKPV 257 I ++ K+E+ + + N I++ SD MVARGDLG E+P+E++ Q+ +I +C KPV Sbjct: 301 IHVIVKIESADSIPNLHSIISASDGAMVARGDLGAELPIEEVPLLQEDIIRRCQSMQKPV 360 Query: 258 VTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAVQTMAKICLQ 437 + AT MLESMI P PTRAE +D++ AV +G D VMLSGETA G YP AV+ M + L+ Sbjct: 361 IVATNMLESMIDHPTPTRAEVSDISIAVREGADAVMLSGETAHGKYPLKAVKVMHIVALR 420 Query: 438 AESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGGTTARLVAKY 617 ES + S + + SS++ AN+ +T I+V TR G+ A +++ Sbjct: 421 TESSLQKSTSSPSQSAAYKSHMGEMFAFHSSSM--ANTL-STPIIVFTRTGSMAIILSHN 477 Query: 618 RPSMPILS 641 RPS + + Sbjct: 478 RPSSTVFA 485
>KPYK_METJA (Q57572) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 447 Score = 130 bits (326), Expect = 5e-30 Identities = 72/196 (36%), Positives = 110/196 (56%) Frame = +3 Query: 54 VLGEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIFK 233 ++ E+ ++SK+E +EG+ N +I +SD MVARGDLG+E+P+E I QK ++ Sbjct: 188 IISEYKGDCEVISKIETKEGLKNIKEIARESDGVMVARGDLGVEVPIENIPIEQKNILRI 247 Query: 234 CNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAVQ 413 N G +TATQ+L+SMI +P PTRAE TD+ANA+ DGTDC+MLS ET G YP A++ Sbjct: 248 ANRYGILSITATQILDSMINNPFPTRAEVTDIANAIYDGTDCLMLSNETTIGKYPIEAIK 307 Query: 414 TMAKICLQAESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGGT 593 + K+ A+ + + E L + L++ T G Sbjct: 308 VLNKVAKVADEHYE-----EFGDRVCLEVESIDEGLVYAVYELYKKLNTKLVITPTYSGR 362 Query: 594 TARLVAKYRPSMPILS 641 TA+L++K R + I++ Sbjct: 363 TAKLISKLRINSKIIA 378
>KPYK_METEX (O05118) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 483 Score = 130 bits (326), Expect = 5e-30 Identities = 73/188 (38%), Positives = 111/188 (59%) Frame = +3 Query: 81 MLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIFKCNIQGKPVV 260 ++M+K+E + + D+I+ SD MVARGDLG+E+P+E++ QK + GKPVV Sbjct: 218 LVMAKIEKPQALTRLDEIIEISDGIMVARGDLGVEMPLEQVPGVQKRITRVARRLGKPVV 277 Query: 261 TATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAVQTMAKICLQA 440 ATQMLESMI SP PTRAE +DVA AV +G D VMLS E+AAG +P A+ TM +I Q Sbjct: 278 VATQMLESMITSPVPTRAEVSDVATAVYEGADAVMLSAESAAGDFPVEAIGTMNRIAEQV 337 Query: 441 ESCVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGGTTARLVAKYR 620 E Y ++ +++A++A + + I+ T G+T +A+ R Sbjct: 338 ERDALYWSILMAQRSEPEPTAS--DAIAAAAHQIVEALSLRSIMAWTHSGSTVLRLARAR 395 Query: 621 PSMPILSV 644 P+ ++++ Sbjct: 396 PNASVIAL 403
>KPYK_THEAC (P32044) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 544 Score = 127 bits (318), Expect = 4e-29 Identities = 71/193 (36%), Positives = 113/193 (58%), Gaps = 2/193 (1%) Frame = +3 Query: 84 LMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIFKCNIQGKPVVT 263 ++SK+E + G+ N ++I+ SD MVARGDLG+E+P++++ AQK +I + G + Sbjct: 199 IISKIETKSGLDNIEEIVKSSDGIMVARGDLGVELPLKEVVLAQKHIIKTAHEDGDFTIV 258 Query: 264 ATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAVQTMAKICLQAE 443 ATQ+LESM+ + PTRAE +D+ NA++D D +MLS E+A G YP AV+T+ ++ E Sbjct: 259 ATQVLESMVNNSSPTRAEISDITNAIIDNADALMLSEESAIGKYPVQAVRTLKEVSDYVE 318 Query: 444 SCV--DYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGGTTARLVAKY 617 V D S FK S+A +A ++ K+ I+ LT G+T R+++ Sbjct: 319 DKVSFDSSYYFKGNTIAY--------SVARAAKILSDDIKSDGIVALTHTGSTVRMISSL 370 Query: 618 RPSMPILSVVVPE 656 RP + + V E Sbjct: 371 RPKAMVYAATVSE 383
>KPYA_RICCO (Q43117) Pyruvate kinase isozyme A, chloroplast precursor (EC| 2.7.1.40) Length = 583 Score = 126 bits (317), Expect = 5e-29 Identities = 68/191 (35%), Positives = 109/191 (57%), Gaps = 3/191 (1%) Frame = +3 Query: 78 IMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIFKCNIQGKPV 257 I +++K+E+ + + N ++I+ SD MVARGDLG +IP+E++ AQ+ ++ C KPV Sbjct: 326 IAVIAKIESIDSLKNLEEIIRASDGAMVARGDLGAQIPLEQVPSAQQNIVQVCRQLNKPV 385 Query: 258 VTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAVQTMAKICLQ 437 + A+Q+LESMI+ P PTRAE DV+ AV D +MLSGE+A G YPE A+ + + ++ Sbjct: 386 IVASQLLESMIEYPTPTRAEVADVSEAVRQRADALMLSGESAMGQYPEKALAVLRSVSVR 445 Query: 438 AESC---VDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGGTTARLV 608 E + + E + +SA + AN+ + V T+ G A L+ Sbjct: 446 IEKWWREEKHHEAMELPAIGSTYSDSISEEICNSAAKMANNLGVDALFVYTKDGHMASLL 505 Query: 609 AKYRPSMPILS 641 ++ RP PI + Sbjct: 506 SRCRPDCPIFA 516
>KPYK_MYCPN (P78031) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 508 Score = 123 bits (309), Expect = 4e-28 Identities = 67/132 (50%), Positives = 87/132 (65%) Frame = +3 Query: 63 EHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIFKCNI 242 ++AK + L++K+E+ + N D I+ SD MVARGDLG+EIP K+ Y Q+ MI C Sbjct: 239 KNAKHVKLIAKIESNHALNNIDGIIKASDGIMVARGDLGLEIPYYKVPYWQRYMIKACRF 298 Query: 243 QGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAVQTMA 422 K V+TATQML+S+ K+ +PTRAE TDV AV G D MLSGETA GA+P AV M Sbjct: 299 FNKRVITATQMLDSLEKNIQPTRAEVTDVYFAVDRGNDATMLSGETANGAFPLNAVYVMK 358 Query: 423 KICLQAESCVDY 458 I Q+E+ DY Sbjct: 359 MIDKQSETFFDY 370
>KPYA_TOBAC (Q40545) Pyruvate kinase isozyme A, chloroplast precursor (EC| 2.7.1.40) Length = 593 Score = 123 bits (309), Expect = 4e-28 Identities = 67/191 (35%), Positives = 109/191 (57%), Gaps = 3/191 (1%) Frame = +3 Query: 78 IMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIFKCNIQGKPV 257 I +++K+E+ + + N ++I+ SD MVARGDLG +IP+E++ Q+ ++ C +PV Sbjct: 336 ISVIAKIESIDSLKNLEEIIQASDGAMVARGDLGAQIPLEQVPSEQQKIVQICRQLNRPV 395 Query: 258 VTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAVQTMAKICLQ 437 + A+Q+LESMI+ P PTRAE DV+ AV D +MLSGE+A G +PE A+ + + L+ Sbjct: 396 IVASQLLESMIEYPIPTRAEVADVSEAVRQRGDALMLSGESAMGQFPEKALTVLRSVSLR 455 Query: 438 AESC---VDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSAKATLILVLTRGGTTARLV 608 E V + E + +SA + AN+ + + V T+ G A L+ Sbjct: 456 IERMWREQKRHEVIELPSIASSFSDSISEEICNSAAKMANNLEVDALFVYTKNGHMASLL 515 Query: 609 AKYRPSMPILS 641 ++ RP PI + Sbjct: 516 SRCRPDCPIFA 526
>KPYK_MYCGE (P47458) Pyruvate kinase (EC 2.7.1.40) (PK)| Length = 508 Score = 120 bits (301), Expect = 4e-27 Identities = 64/132 (48%), Positives = 86/132 (65%) Frame = +3 Query: 63 EHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIFKCNI 242 ++A + +++K+E+ + N D I+ SD MVARGDLG+EIP ++ Y Q+ MI C Sbjct: 239 KNASGVKIIAKIESNHALNNIDKIIKASDGIMVARGDLGLEIPYYQVPYWQRYMIKACRF 298 Query: 243 QGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAVQTMA 422 K +TATQML+S+ K+ +PTRAE TDV AV G D MLSGETA+G YP AV M Sbjct: 299 FNKRSITATQMLDSLEKNIQPTRAEVTDVYFAVDRGNDATMLSGETASGLYPLNAVAVMQ 358 Query: 423 KICLQAESCVDY 458 KI Q+E+ DY Sbjct: 359 KIDKQSETFFDY 370
>OR2W3_HUMAN (Q7Z3T1) Olfactory receptor 2W3 (Olfactory receptor OR1-49)| Length = 314 Score = 32.3 bits (72), Expect = 1.3 Identities = 15/43 (34%), Positives = 25/43 (58%) Frame = -3 Query: 139 ARISSKLATPSWFSTFDISIIDLACSPSTXPDLHKXLNPCEQT 11 +R+ L TP +F +S +DL+ + S+ P L LN C++T Sbjct: 49 SRLDPHLHTPMYFFLAHLSFLDLSFTTSSIPQLLYNLNGCDKT 91
>RL10_SYNPX (Q7U3T8) 50S ribosomal protein L10| Length = 175 Score = 31.6 bits (70), Expect = 2.2 Identities = 12/55 (21%), Positives = 30/55 (54%) Frame = +3 Query: 42 RSGKVLGEHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIF 206 R+G + + K+ ++ ++ +N D +L ++AF++ +GD+G + + F Sbjct: 46 RAGNAVCKVTKNTLMRRAIDGDSAWSNLDSLLTGTNAFVLIKGDVGAGVKAVQAF 100
>VSM5_TRYBB (P26333) Variant surface glycoprotein MITAT 1.5 precursor (VSG 118)| Length = 474 Score = 31.2 bits (69), Expect = 2.9 Identities = 27/96 (28%), Positives = 41/96 (42%), Gaps = 1/96 (1%) Frame = +3 Query: 270 QMLESMIKSPRPTRAEATDVAN-AVLDGTDCVMLSGETAAGAYPELAVQTMAKICLQAES 446 Q +++ K + +A A AN A L T+ + L AA P T +A+ Sbjct: 31 QKAQAICKMSKELKATAMRAANDAKLKITEILELENVFAA-MIPNATKGT------EADG 83 Query: 447 CVDYSAVFKXXXXXXXXXXXXLESLASSAVRTANSA 554 C DY+AVF + +LA SA + A +A Sbjct: 84 CTDYNAVFLEANNTAAETVSKIATLAESATKAAGAA 119
>KPC1_YEAST (P24583) Protein kinase C-like 1 (EC 2.7.11.13) (PKC 1)| Length = 1151 Score = 30.4 bits (67), Expect = 4.9 Identities = 31/134 (23%), Positives = 53/134 (39%), Gaps = 6/134 (4%) Frame = +3 Query: 63 EHAKSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIFYAQKVMIFKCNI 242 +H +S M K E+ + D I A++ R +IPVEK + + K N Sbjct: 222 DHIQSPMFARKPESYVTIKIDDTIKARTKPSRNDRWSEDFQIPVEKGNEIEITVYDKVND 281 Query: 243 QGKPVVTATQMLESMIKSPRPTRAEATDV------ANAVLDGTDCVMLSGETAAGAYPEL 404 PV +L + + R +A T+ A+ + G+ G T Y Sbjct: 282 SLIPVAIMWLLLSDIAEEIRKKKAGQTNEQQGWVNASNINGGSSLASEEGSTLTSTYSNS 341 Query: 405 AVQTMAKICLQAES 446 A+Q+ + +Q E+ Sbjct: 342 AIQSTSAKNVQGEN 355
>RL10_SYNS9 (Q3AUJ7) 50S ribosomal protein L10| Length = 175 Score = 30.0 bits (66), Expect = 6.4 Identities = 11/45 (24%), Positives = 25/45 (55%) Frame = +3 Query: 72 KSIMLMSKVENQEGVANFDDILAQSDAFMVARGDLGMEIPVEKIF 206 K+ ++ ++ AN D +L ++AF++ +GD+G + + F Sbjct: 56 KNTLMRRAIDGDSSWANLDSLLTGTNAFVLVKGDVGAGVKAVRSF 100
>ILVB_SCHPO (P36620) Acetolactate synthase, mitochondrial precursor (EC| 2.2.1.6) (Acetohydroxy-acid synthase) (ALS) (AHAS) Length = 669 Score = 29.6 bits (65), Expect = 8.3 Identities = 29/109 (26%), Positives = 46/109 (42%) Frame = +3 Query: 321 TDVANAVLDGTDCVMLSGETAAGAYPELAVQTMAKICLQAESCVDYSAVFKXXXXXXXXX 500 T +A+A+ DGT V+ SG+ A A A Q + + + SC ++ + K Sbjct: 167 TPIADALADGTPLVVFSGQVATSAIGSDAFQEADMVGI-SRSCTKWNVMVK--------D 217 Query: 501 XXXLESLASSAVRTANSAKATLILVLTRGGTTARLVAKYRPSMPILSVV 647 L A A S + +LV TA ++ + +PILS V Sbjct: 218 VADLPRRIDEAFEIATSGRPGPVLVDLPKDVTASVL---KEPIPILSSV 263 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 96,754,201 Number of Sequences: 219361 Number of extensions: 1986072 Number of successful extensions: 5375 Number of sequences better than 10.0: 84 Number of HSP's better than 10.0 without gapping: 5161 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5351 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 6314008338 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
