>GLO2N_ARATH (Q9SID3) Putative hydroxyacylglutathione hydrolase 2, mitochondrial|
           precursor (EC 3.1.2.6) (Glyoxalase II) (Glx II)
          Length = 324

 Score =  231 bits (590), Expect = 1e-60
 Identities = 106/157 (67%), Positives = 131/157 (83%)
 Frame = +1

Query: 1   VFAGHQVLVMETPGHTSGHVSFYFPGSGAIFTGDTLFSLSCGKLFEGTPEQMYSSLQKIV 180
           +FAGH+V VM+TPGHT GH+S YFPGS AIFTGDT+FSLSCGKLFEGTP+QM +SLQKI 
Sbjct: 168 MFAGHEVHVMDTPGHTKGHISLYFPGSRAIFTGDTMFSLSCGKLFEGTPKQMLASLQKIT 227

Query: 181 ALPDVTKVYCGHEYTLSNSRFALSIEPGNEELQEYAASTADLRNKNTPTVPTTIAREKQC 360
           +LPD T +YCGHEYTLSNS+FALS+EP NE LQ YAA  A+LR+K  PT+PTT+  EK C
Sbjct: 228 SLPDDTSIYCGHEYTLSNSKFALSLEPNNEVLQSYAAHVAELRSKKLPTIPTTVKMEKAC 287

Query: 361 NPFLRTSSPEIKKRLSIPDHFDDARVLEVIRRAKDNF 471
           NPFLR+S+ +I++ L IP+  D+A  L +IR+AKD+F
Sbjct: 288 NPFLRSSNTDIRRALRIPEAADEAEALGIIRKAKDDF 324

>GLO2M_ARATH (O24495) Hydroxyacylglutathione hydrolase 1, mitochondrial|
           precursor (EC 3.1.2.6) (Glyoxalase II) (Glx II)
          Length = 331

 Score =  207 bits (528), Expect = 2e-53
 Identities = 97/157 (61%), Positives = 119/157 (75%)
 Frame = +1

Query: 1   VFAGHQVLVMETPGHTSGHVSFYFPGSGAIFTGDTLFSLSCGKLFEGTPEQMYSSLQKIV 180
           +FAGH+V +++TPGHT GH+SFYFPGS  IFTGD ++SLSCG L EGTPEQM SSLQKIV
Sbjct: 175 MFAGHEVRILDTPGHTQGHISFYFPGSATIFTGDLIYSLSCGTLSEGTPEQMLSSLQKIV 234

Query: 181 ALPDVTKVYCGHEYTLSNSRFALSIEPGNEELQEYAASTADLRNKNTPTVPTTIAREKQC 360
           +LPD T +YCG E T  N +FALS+EP NE LQ YA   A LR++  P++PTT+  EK C
Sbjct: 235 SLPDDTNIYCGRENTAGNLKFALSVEPKNETLQSYATRVAHLRSQGLPSIPTTVKVEKAC 294

Query: 361 NPFLRTSSPEIKKRLSIPDHFDDARVLEVIRRAKDNF 471
           NPFLR SS +I+K LSIPD   +A  L  I+RA+D F
Sbjct: 295 NPFLRISSKDIRKSLSIPDSATEAEALRRIQRARDRF 331

>GLO2_SYNY3 (P72933) Probable hydroxyacylglutathione hydrolase (EC 3.1.2.6)|
           (Glyoxalase II) (Glx II)
          Length = 257

 Score =  144 bits (363), Expect = 3e-34
 Identities = 72/161 (44%), Positives = 103/161 (63%), Gaps = 5/161 (3%)
 Frame = +1

Query: 4   FAGHQVLVMETPGHTSGHVSFYF-PGSGA----IFTGDTLFSLSCGKLFEGTPEQMYSSL 168
           FA  +  V   PGHT GH+++YF PGSG     +F GDT+F+  CG+LFEGTP QM  S+
Sbjct: 100 FADREATVYFVPGHTRGHIAYYFAPGSGETIGDLFCGDTIFAGGCGRLFEGTPAQMVQSI 159

Query: 169 QKIVALPDVTKVYCGHEYTLSNSRFALSIEPGNEELQEYAASTADLRNKNTPTVPTTIAR 348
            K+  LPD T+++C HEYTL N +FAL+++P N++LQE   +    R +   T+P+ +  
Sbjct: 160 GKLRQLPDQTRLWCAHEYTLGNLKFALTVDPSNKDLQERFQTVQGDRQRGQATIPSWLGT 219

Query: 349 EKQCNPFLRTSSPEIKKRLSIPDHFDDARVLEVIRRAKDNF 471
           EK+ NPFLR  +P I+ R+ +    + ARV   +R  KDNF
Sbjct: 220 EKRTNPFLRWDNPAIQARVGMT---EPARVFGKLRGMKDNF 257

>GLO2C_ARATH (O24496) Hydroxyacylglutathione hydrolase cytoplasmic (EC 3.1.2.6)|
           (Glyoxalase II) (Glx II)
          Length = 258

 Score =  142 bits (357), Expect = 1e-33
 Identities = 71/156 (45%), Positives = 96/156 (61%), Gaps = 5/156 (3%)
 Frame = +1

Query: 19  VLVMETPGHTSGHVSFYFPG----SGAIFTGDTLFSLSCGKLFEGTPEQMYSSL-QKIVA 183
           +L + TP HT GH+S+Y  G    + A+FTGDTLF   CGK FEGT EQMY SL   + A
Sbjct: 104 ILALHTPCHTKGHISYYVNGKEGENPAVFTGDTLFVAGCGKFFEGTAEQMYQSLCVTLAA 163

Query: 184 LPDVTKVYCGHEYTLSNSRFALSIEPGNEELQEYAASTADLRNKNTPTVPTTIAREKQCN 363
           LP  T+VYCGHEYT+ N  FAL++EP N ++Q+  A     R  + PT+P+T+  E + N
Sbjct: 164 LPKPTQVYCGHEYTVKNLEFALTVEPNNGKIQQKLAWARQQRQADLPTIPSTLEEELETN 223

Query: 364 PFLRTSSPEIKKRLSIPDHFDDARVLEVIRRAKDNF 471
           PF+R   PEI+++L      D  R    +R  KD +
Sbjct: 224 PFMRVDKPEIQEKLGCKSPIDTMR---EVRNKKDQW 256

>GLO2_RHOCA (P96981) Probable hydroxyacylglutathione hydrolase (EC 3.1.2.6)|
           (Glyoxalase II) (Glx II)
          Length = 256

 Score =  139 bits (351), Expect = 6e-33
 Identities = 65/149 (43%), Positives = 89/149 (59%)
 Frame = +1

Query: 25  VMETPGHTSGHVSFYFPGSGAIFTGDTLFSLSCGKLFEGTPEQMYSSLQKIVALPDVTKV 204
           V+   GHT GH+++Y PG+G +F+GD+L S  CG+LFEGTP QM+ +L ++ ALP  T+V
Sbjct: 108 VIAADGHTLGHIAWYLPGAGLLFSGDSLMSWGCGRLFEGTPAQMFDTLTRLAALPPETRV 167

Query: 205 YCGHEYTLSNSRFALSIEPGNEELQEYAASTADLRNKNTPTVPTTIAREKQCNPFLRTSS 384
             GHEYT +N RFALS+EPGN  L +       LR    P++P T+  E+  NPFLR   
Sbjct: 168 CSGHEYTAANGRFALSLEPGNGRLHDRMDRVTALRLAGEPSLPVTLGEERATNPFLRADD 227

Query: 385 PEIKKRLSIPDHFDDARVLEVIRRAKDNF 471
             ++  L +P       V    R  KD F
Sbjct: 228 AALRAALGLPGDAAPLAVFTAARARKDRF 256

>GLO2_RHOBL (P05446) Probable hydroxyacylglutathione hydrolase (EC 3.1.2.6)|
           (Glyoxalase II) (Glx II)
          Length = 255

 Score =  136 bits (342), Expect = 7e-32
 Identities = 66/150 (44%), Positives = 93/150 (62%)
 Frame = +1

Query: 22  LVMETPGHTSGHVSFYFPGSGAIFTGDTLFSLSCGKLFEGTPEQMYSSLQKIVALPDVTK 201
           +V++ PGHT GH++F+FPGS   FTGD+L +  CG+LFEGTP +M++SL K+ ALP  T 
Sbjct: 107 VVIDVPGHTRGHIAFHFPGSALAFTGDSLMAAGCGRLFEGTPAEMWASLSKLAALPPETL 166

Query: 202 VYCGHEYTLSNSRFALSIEPGNEELQEYAASTADLRNKNTPTVPTTIAREKQCNPFLRTS 381
           +  GH+Y   N RFAL++EPGN  L       +++R +    +P T+A E   NPFLR  
Sbjct: 167 ICSGHDYLDGNLRFALALEPGNPALISRQGRLSEMRREGRLPMPWTLAEELATNPFLRAP 226

Query: 382 SPEIKKRLSIPDHFDDARVLEVIRRAKDNF 471
            P++K  + +P    D  V   IR  KD F
Sbjct: 227 LPQMKAAVGLP-QASDTVVFAEIRARKDLF 255

>GLO2_ECOLI (P0AC84) Probable hydroxyacylglutathione hydrolase (EC 3.1.2.6)|
           (Glyoxalase II) (Glx II)
          Length = 251

 Score =  129 bits (324), Expect = 8e-30
 Identities = 64/128 (50%), Positives = 83/128 (64%)
 Frame = +1

Query: 10  GHQVLVMETPGHTSGHVSFYFPGSGAIFTGDTLFSLSCGKLFEGTPEQMYSSLQKIVALP 189
           GH+  V+ TPGHT GH+ ++      +F GDTLFS  CG+LFEGT  QMY SL+K+ ALP
Sbjct: 99  GHEFSVIATPGHTLGHICYF--SKPYLFCGDTLFSGGCGRLFEGTASQMYQSLKKLSALP 156

Query: 190 DVTKVYCGHEYTLSNSRFALSIEPGNEELQEYAASTADLRNKNTPTVPTTIAREKQCNPF 369
           D T V C HEYTLSN +FALSI P +  + +Y     +LR KN  T+P  +  E+Q N F
Sbjct: 157 DDTLVCCAHEYTLSNMKFALSILPHDLSINDYYRKVKELRAKNQITLPVILKNERQINVF 216

Query: 370 LRTSSPEI 393
           LRT   ++
Sbjct: 217 LRTEDIDL 224

>GLO2_ECO57 (P0AC85) Probable hydroxyacylglutathione hydrolase (EC 3.1.2.6)|
           (Glyoxalase II) (Glx II)
          Length = 251

 Score =  129 bits (324), Expect = 8e-30
 Identities = 64/128 (50%), Positives = 83/128 (64%)
 Frame = +1

Query: 10  GHQVLVMETPGHTSGHVSFYFPGSGAIFTGDTLFSLSCGKLFEGTPEQMYSSLQKIVALP 189
           GH+  V+ TPGHT GH+ ++      +F GDTLFS  CG+LFEGT  QMY SL+K+ ALP
Sbjct: 99  GHEFSVIATPGHTLGHICYF--SKPYLFCGDTLFSGGCGRLFEGTASQMYQSLKKLSALP 156

Query: 190 DVTKVYCGHEYTLSNSRFALSIEPGNEELQEYAASTADLRNKNTPTVPTTIAREKQCNPF 369
           D T V C HEYTLSN +FALSI P +  + +Y     +LR KN  T+P  +  E+Q N F
Sbjct: 157 DDTLVCCAHEYTLSNMKFALSILPHDLSINDYYRKVKELRAKNQITLPVILKNERQINVF 216

Query: 370 LRTSSPEI 393
           LRT   ++
Sbjct: 217 LRTEDIDL 224

>GLO2_MOUSE (Q99KB8) Hydroxyacylglutathione hydrolase (EC 3.1.2.6) (Glyoxalase|
           II) (Glx II)
          Length = 260

 Score =  129 bits (323), Expect = 1e-29
 Identities = 68/157 (43%), Positives = 93/157 (59%), Gaps = 6/157 (3%)
 Frame = +1

Query: 19  VLVMETPGHTSGHVSFYF--PGSG---AIFTGDTLFSLSCGKLFEGTPEQMYSSLQKIVA 183
           V  + TP HTSGH+ ++   PGS    A+FTGDTLF   CGK +EGT ++MY +L +++ 
Sbjct: 102 VKCLSTPCHTSGHICYFVSKPGSSEPSAVFTGDTLFVAGCGKFYEGTADEMYKALLEVLG 161

Query: 184 -LPDVTKVYCGHEYTLSNSRFALSIEPGNEELQEYAASTADLRNKNTPTVPTTIAREKQC 360
            LP  TKVYCGHEYT++N +FA  +EPGN  +QE  A   +      PTVP+T+A E   
Sbjct: 162 RLPPDTKVYCGHEYTVNNLKFARHVEPGNAAIQEKLAWAKEKYAIGEPTVPSTLAEEFTY 221

Query: 361 NPFLRTSSPEIKKRLSIPDHFDDARVLEVIRRAKDNF 471
           NPF+R     +++        D    +  IRR KD F
Sbjct: 222 NPFMRVKEKTVQQHAG---ETDPVTTMRAIRREKDQF 255

>GLO2_RAT (O35952) Hydroxyacylglutathione hydrolase (EC 3.1.2.6) (Glyoxalase|
           II) (Glx II) (Round spermatid protein RSP29)
          Length = 260

 Score =  126 bits (316), Expect = 7e-29
 Identities = 67/157 (42%), Positives = 92/157 (58%), Gaps = 6/157 (3%)
 Frame = +1

Query: 19  VLVMETPGHTSGHVSFYF--PGSG---AIFTGDTLFSLSCGKLFEGTPEQMYSSLQKIVA 183
           V  + TP HTSGH+ ++   PGS    A+FTGDTLF   CGK +EGT ++MY +L +++ 
Sbjct: 102 VKCLSTPCHTSGHICYFVSKPGSSEPSAVFTGDTLFVAGCGKFYEGTADEMYKALLEVLG 161

Query: 184 -LPDVTKVYCGHEYTLSNSRFALSIEPGNEELQEYAASTADLRNKNTPTVPTTIAREKQC 360
            LP  TKV CGHEYT++N +FA  +EPGN  +QE  A   +      PTVP+T+A E   
Sbjct: 162 RLPPDTKVICGHEYTVNNLKFARHVEPGNTAVQEKLAWAKEKNAIGEPTVPSTLAEEFTY 221

Query: 361 NPFLRTSSPEIKKRLSIPDHFDDARVLEVIRRAKDNF 471
           NPF+R     +++        D    +  IRR KD F
Sbjct: 222 NPFMRVKEKTVQQHAG---ETDPVTTMRAIRREKDQF 255

>GLO2_HUMAN (Q16775) Hydroxyacylglutathione hydrolase (EC 3.1.2.6) (Glyoxalase|
           II) (GLX II)
          Length = 260

 Score =  121 bits (304), Expect = 2e-27
 Identities = 62/157 (39%), Positives = 91/157 (57%), Gaps = 6/157 (3%)
 Frame = +1

Query: 19  VLVMETPGHTSGHVSFYFPGSG-----AIFTGDTLFSLSCGKLFEGTPEQMYSSLQKIVA 183
           V  + TP HTSGH+ ++    G     A+FTGDTLF   CGK +EGT ++M  +L +++ 
Sbjct: 102 VKCLATPCHTSGHICYFVSKPGGSEPPAVFTGDTLFVAGCGKFYEGTADEMCKALLEVLG 161

Query: 184 -LPDVTKVYCGHEYTLSNSRFALSIEPGNEELQEYAASTADLRNKNTPTVPTTIAREKQC 360
            LP  T+VYCGHEYT++N +FA  +EPGN  ++E  A   +  +   PTVP+T+A E   
Sbjct: 162 RLPPDTRVYCGHEYTINNLKFARHVEPGNAAIREKLAWAKEKYSIGEPTVPSTLAEEFTY 221

Query: 361 NPFLRTSSPEIKKRLSIPDHFDDARVLEVIRRAKDNF 471
           NPF+R     +++        D    +  +RR KD F
Sbjct: 222 NPFMRVREKTVQQHAG---ETDPVTTMRAVRREKDQF 255

>GLO2_SCHMA (Q26547) Probable hydroxyacylglutathione hydrolase (EC 3.1.2.6)|
           (Glyoxalase II) (Glx II)
          Length = 240

 Score =  120 bits (301), Expect = 4e-27
 Identities = 63/149 (42%), Positives = 87/149 (58%), Gaps = 6/149 (4%)
 Frame = +1

Query: 43  HTSGHVSFYFPGS-----GAIFTGDTLFSLSCGKLFEGTPEQMYSSLQKIVA-LPDVTKV 204
           HT+GH+ +          GA+FTGDTLF   CG+ FEGT EQM+ +L ++++ LP  TKV
Sbjct: 95  HTTGHICYLVTEENSTKEGAVFTGDTLFLGGCGRFFEGTAEQMFKALIEVLSKLPTTTKV 154

Query: 205 YCGHEYTLSNSRFALSIEPGNEELQEYAASTADLRNKNTPTVPTTIAREKQCNPFLRTSS 384
           YCGHEYT+ N  F L++EP NE L+    +   LR  N  +VP TI  E   NP +R S 
Sbjct: 155 YCGHEYTVKNLEFGLTVEPKNEALKHRLEAVKRLRASNQASVPGTIGEELATNPLMRVSE 214

Query: 385 PEIKKRLSIPDHFDDARVLEVIRRAKDNF 471
           P++   L+     D  + ++ IR  KD F
Sbjct: 215 PDV---LAHAKTTDPIKAMKTIREEKDRF 240

>GLO2_CALJA (Q28333) Hydroxyacylglutathione hydrolase (EC 3.1.2.6) (Glyoxalase|
           II) (Glx II) (Germ cell-specific protein)
          Length = 260

 Score =  116 bits (290), Expect = 7e-26
 Identities = 60/157 (38%), Positives = 88/157 (56%), Gaps = 6/157 (3%)
 Frame = +1

Query: 19  VLVMETPGHTSGHVSFYFPGSG-----AIFTGDTLFSLSCGKLFEGTPEQMYSSLQKIVA 183
           V  + TP HTSGH+ ++    G     A+FTGDTLF   CGK +EGT ++M  +L +++ 
Sbjct: 102 VKCLSTPCHTSGHICYFVTKPGGSQPPAVFTGDTLFVAGCGKFYEGTADEMCKALLEVLG 161

Query: 184 -LPDVTKVYCGHEYTLSNSRFALSIEPGNEELQEYAASTADLRNKNTPTVPTTIAREKQC 360
             P  T+VYCGHEYT++N +FA  +E GN  +QE  A   +  +   P VP+T+A E   
Sbjct: 162 RFPPDTRVYCGHEYTINNLKFARHVESGNAAVQEKLAWAKEKYSIGEPAVPSTLAEEFTY 221

Query: 361 NPFLRTSSPEIKKRLSIPDHFDDARVLEVIRRAKDNF 471
           NPF+R     +++        D    +  +RR KD F
Sbjct: 222 NPFMRVREKTVQQHAG---ETDPVPTMRAVRREKDQF 255

>GLO2_BUCAP (Q08889) Probable hydroxyacylglutathione hydrolase (EC 3.1.2.6)|
           (Glyoxalase II) (Glx II)
          Length = 250

 Score =  113 bits (282), Expect = 6e-25
 Identities = 60/152 (39%), Positives = 90/152 (59%)
 Frame = +1

Query: 16  QVLVMETPGHTSGHVSFYFPGSGAIFTGDTLFSLSCGKLFEGTPEQMYSSLQKIVALPDV 195
           ++ V  TPGHT GHVS+Y      IF GDTLFS  CG++F+     MY S+  I +LP  
Sbjct: 101 EIHVFLTPGHTLGHVSYYL--KPYIFCGDTLFSGGCGRVFKNKFFDMYQSINFIKSLPKK 158

Query: 196 TKVYCGHEYTLSNSRFALSIEPGNEELQEYAASTADLRNKNTPTVPTTIAREKQCNPFLR 375
           T + C HEYTLSN  FA+SI P ++++++Y        ++N  ++P ++  EK+ N FLR
Sbjct: 159 TILCCSHEYTLSNLNFAMSILPFDKKIKKYYKKIKKHISQNKTSLPVSLETEKKINIFLR 218

Query: 376 TSSPEIKKRLSIPDHFDDARVLEVIRRAKDNF 471
           T+   IKK + +        V  ++R+ KD+F
Sbjct: 219 TNEKTIKKAMGLKKDTSSFEVFILLRKEKDDF 250

>GLO2_BUCAI (P57336) Probable hydroxyacylglutathione hydrolase (EC 3.1.2.6)|
           (Glyoxalase II) (GLX II)
          Length = 251

 Score =  107 bits (266), Expect = 4e-23
 Identities = 59/147 (40%), Positives = 84/147 (57%)
 Frame = +1

Query: 25  VMETPGHTSGHVSFYFPGSGAIFTGDTLFSLSCGKLFEGTPEQMYSSLQKIVALPDVTKV 204
           V  TPGHTSGHVS+Y      IF GDTLFS  CG++F+    +MY S++ I +LPD T +
Sbjct: 104 VFFTPGHTSGHVSYY--SQPYIFCGDTLFSAGCGRVFKNKHLEMYRSIKIISSLPDSTLL 161

Query: 205 YCGHEYTLSNSRFALSIEPGNEELQEYAASTADLRNKNTPTVPTTIAREKQCNPFLRTSS 384
            C HEYTLSN +F++ I P +  ++ Y             ++P+ I  EK+ N FLRT+ 
Sbjct: 162 CCSHEYTLSNLQFSMFILPNDNFIKLYLKKIEIKLKLGQSSLPSYIFFEKKINLFLRTND 221

Query: 385 PEIKKRLSIPDHFDDARVLEVIRRAKD 465
             +KK + +     D  V + +R  KD
Sbjct: 222 NYVKKSIGLKSTCTDFEVFKRLRLKKD 248

>GLO2_BUCBP (Q89AN4) Probable hydroxyacylglutathione hydrolase (EC 3.1.2.6)|
           (Glyoxalase II) (Glx II)
          Length = 249

 Score = 97.1 bits (240), Expect = 5e-20
 Identities = 49/129 (37%), Positives = 79/129 (61%)
 Frame = +1

Query: 25  VMETPGHTSGHVSFYFPGSGAIFTGDTLFSLSCGKLFEGTPEQMYSSLQKIVALPDVTKV 204
           ++ TPGHT+GH ++Y P    +F GD++FS  CG++  G   +MY+SL+ I  LP+ T +
Sbjct: 104 IIPTPGHTNGHTAYYCPPF--LFCGDSIFSGGCGRVKNGMMIKMYNSLRTISKLPNDTLI 161

Query: 205 YCGHEYTLSNSRFALSIEPGNEELQEYAASTADLRNKNTPTVPTTIAREKQCNPFLRTSS 384
           YC HEYT SN  F   I P N  +  Y  +    ++K   T+P+T+  EK+ NPFL+ ++
Sbjct: 162 YCSHEYTRSNLEFFKKIFPKNLNILNYYNNIK--KSKTQCTLPSTLKIEKKINPFLQLNN 219

Query: 385 PEIKKRLSI 411
             ++ ++ I
Sbjct: 220 TNLRHQVKI 228

>GLO2_HAEIN (P71374) Probable hydroxyacylglutathione hydrolase (EC 3.1.2.6)|
           (Glyoxalase II) (Glx II)
          Length = 238

 Score = 89.7 bits (221), Expect = 7e-18
 Identities = 50/133 (37%), Positives = 73/133 (54%), Gaps = 5/133 (3%)
 Frame = +1

Query: 7   AGHQVLVMETPGHTSGHVSFYFPGSGAIFTGDTLFSLSCGKLFEGTPEQMYSSLQKIVAL 186
           A +Q+ V+ T GHT  HVSF       +F GD LFS  CG++F G    M+  LQ++  L
Sbjct: 96  ANYQIDVIPTGGHTKQHVSFLVDNH--LFCGDALFSAGCGRVFTGNYALMFEGLQRLNTL 153

Query: 187 PDVTKVYCGHEYTLSNSRFALSIEPGNEELQEYAASTADL-----RNKNTPTVPTTIARE 351
           PD T V   HEYTL N  FA ++      +++ A     +     R +N P++PTT+  E
Sbjct: 154 PDETIVCPAHEYTLGNLAFAETVLVDKSAVEKSAVEKQRIFVETQRAENKPSLPTTLKLE 213

Query: 352 KQCNPFLRTSSPE 390
           ++ NPFL+  + E
Sbjct: 214 REINPFLQAKTLE 226

>GLO2_YEAST (Q05584) Hydroxyacylglutathione hydrolase, cytoplasmic isozyme (EC|
           3.1.2.6) (Glyoxalase II) (Glx II)
          Length = 274

 Score = 73.6 bits (179), Expect = 5e-13
 Identities = 48/167 (28%), Positives = 81/167 (48%), Gaps = 17/167 (10%)
 Frame = +1

Query: 16  QVLVMETPGHTSGHVSFYFPG----SGAIFTGDTLFSLSCGKLFEGTPEQMYSSLQKIVA 183
           ++  + TP HT   + +Y          IFTGDTLF+  CG+ FEGT E+M  +L   + 
Sbjct: 112 EITCIRTPCHTRDSICYYVKDPTTDERCIFTGDTLFTAGCGRFFEGTGEEMDIALNNSIL 171

Query: 184 LP------DVTKVYCGHEYTLSNSRFALSIEP------GNEELQEYAASTADLRNKNTPT 327
                     T+VY GHEYT  N +F   I P        +EL+++ +       +    
Sbjct: 172 ETVGRQNWSKTRVYPGHEYTSDNVKFVRKIYPQVGENKALDELEQFCSKHEVTAGR---- 227

Query: 328 VPTTIAREKQCNPFLRTSSPEIKKRLSIPDH-FDDARVLEVIRRAKD 465
              T+  E + NPF+R   P+++K     ++ +D A++++ +R  K+
Sbjct: 228 --FTLKDEVEFNPFMRLEDPKVQKAAGDTNNSWDRAQIMDKLRAMKN 272

>GLO4_YEAST (Q12320) Hydroxyacylglutathione hydrolase, mitochondrial precursor|
           (EC 3.1.2.6) (Glyoxalase II) (Glx II)
          Length = 285

 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 49/164 (29%), Positives = 76/164 (46%), Gaps = 14/164 (8%)
 Frame = +1

Query: 16  QVLVMETPGHTSGHVSFYFP----GSGAIFTGDTLFSLSCGKLFEGTPEQMYSSLQKIVA 183
           +V  + TP HT   + +Y      G   IFTGDTLF   CG+ FEGT   M  +L +I+ 
Sbjct: 122 RVTCIRTPCHTKDSICYYIKDLETGEQCIFTGDTLFIAGCGRFFEGTGRDMDMALNQIML 181

Query: 184 LP------DVTKVYCGHEYTLSNSRF-ALSIEPGNEELQEYAASTADLRNKNTPTVPTTI 342
                   +  K+Y GHEYT  N  F    I     + +E+ A     ++    T   T+
Sbjct: 182 RAVGETNWNKVKIYPGHEYTKGNVSFIRAKIYSDIGQNKEFDALEQYCKSNECTTGHFTL 241

Query: 343 AREKQCNPFLRTSSPEIKKRLSIPD---HFDDARVLEVIRRAKD 465
             E   NPF+R     +  RL++ D    +  + V++ +R+ K+
Sbjct: 242 RDELGYNPFMRLDDRAV--RLAVGDTAGTYPRSVVMQELRKLKN 283

>GLO2O_ARATH (Q9C8L4) Putative hydroxyacylglutathione hydrolase 3, mitochondrial|
           precursor (EC 3.1.2.6) (Glyoxalase II) (Glx II)
          Length = 256

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 35/103 (33%), Positives = 48/103 (46%), Gaps = 10/103 (9%)
 Frame = +1

Query: 25  VMETPGHTSGHVSFYFPGSGA-------IFTGDTLFSLSCGK--LFEGTPEQMYSSL-QK 174
           V  TPGHT+G V+ Y  G GA        FTGD +    CG+    EG+ +Q+Y S+  +
Sbjct: 122 VRATPGHTAGCVT-YVTGEGADQPQPRMAFTGDAVLIRGCGRTDFQEGSSDQLYESVHSQ 180

Query: 175 IVALPDVTKVYCGHEYTLSNSRFALSIEPGNEELQEYAASTAD 303
           I  LP  T +Y  H+Y          +    EE+Q     T D
Sbjct: 181 IFTLPKDTLIYPAHDYK------GFEVSTVGEEMQHNPRLTKD 217

>Y493_MYCLE (Q49649) Hypothetical protein ML0493|
          Length = 218

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 29/70 (41%), Positives = 40/70 (57%), Gaps = 4/70 (5%)
 Frame = +1

Query: 19  VLVMETPGHTSGHVSFYFPG-SGAIFTGDTLFSLSCGK--LFEGTPEQMYSSL-QKIVAL 186
           V V  TPGHT G V F+    +  + TGDTLF  + G+  LF G+   +Y S+ +K++ L
Sbjct: 130 VNVDHTPGHTRGSVCFWVAADTDVVLTGDTLFERTIGRTDLFGGSGRDLYRSIVEKLLVL 189

Query: 187 PDVTKVYCGH 216
            D T V  GH
Sbjct: 190 DDKTVVLPGH 199

>YQGX_BACSU (P54501) Hypothetical protein yqgX|
          Length = 211

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 24/64 (37%), Positives = 37/64 (57%), Gaps = 3/64 (4%)
 Frame = +1

Query: 34  TPGHTSGHVSFYFPGSGAIFTGDTLFSLSCGK--LFEGTPEQMYSSL-QKIVALPDVTKV 204
           TPGH+ G VS+Y   +  + +GD LF    G+  L  G  E + +S+ +K++ LP+ T V
Sbjct: 127 TPGHSPGSVSYYVKDADLVISGDVLFQGGIGRTDLIGGNQETLLTSIHEKLLTLPEHTLV 186

Query: 205 YCGH 216
             GH
Sbjct: 187 LSGH 190

>ETHE1_MOUSE (Q9DCM0) ETHE1 protein, mitochondrial precursor (EC 3.-.-.-)|
           (Ethylmalonic encephalopathy protein 1 homolog)
           (Hepatoma subtracted clone one protein)
          Length = 254

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 24/66 (36%), Positives = 34/66 (51%), Gaps = 3/66 (4%)
 Frame = +1

Query: 34  TPGHTSGHVSFYFPGSGAIFTGDTLFSLSCGK--LFEGTPEQMYSSL-QKIVALPDVTKV 204
           +PGHT G V+F        FTGD L    CG+    +G  + +Y S+ +KI  LP    +
Sbjct: 132 SPGHTPGCVTFVLNDQSMAFTGDALLIRGCGRTDFQQGCAKTLYHSVHEKIFTLPGNCLI 191

Query: 205 YCGHEY 222
           Y  H+Y
Sbjct: 192 YPAHDY 197

>ETHE1_HUMAN (O95571) ETHE1 protein, mitochondrial precursor (EC 3.-.-.-)|
           (Ethylmalonic encephalopathy protein 1) (Hepatoma
           subtracted clone one protein)
          Length = 254

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 24/66 (36%), Positives = 34/66 (51%), Gaps = 3/66 (4%)
 Frame = +1

Query: 34  TPGHTSGHVSFYFPGSGAIFTGDTLFSLSCGK--LFEGTPEQMYSSL-QKIVALPDVTKV 204
           +PGHT G V+F        FTGD L    CG+    +G  + +Y S+ +KI  LP    +
Sbjct: 132 SPGHTPGCVTFVLNDHSMAFTGDALLIRGCGRTDFQQGCAKTLYHSVHEKIFTLPGDCLI 191

Query: 205 YCGHEY 222
           Y  H+Y
Sbjct: 192 YPAHDY 197

>Y2135_AQUAE (O67893) Hypothetical protein aq_2135|
          Length = 211

 Score = 40.0 bits (92), Expect = 0.007
 Identities = 27/77 (35%), Positives = 38/77 (49%), Gaps = 5/77 (6%)
 Frame = +1

Query: 25  VMETPGHTSGHVSFYFPGSGAIFTGDTLFSLSCGK--LFEGTPEQMYSSLQKIVA-LPDV 195
           V+ TPGHT G    Y      +  GD LF  S G+  L  G   ++  S+++++  LP  
Sbjct: 123 VLHTPGHTPGLCCLYEEKRRVLIAGDLLFKGSVGRWDLPGGNLVELKKSVKRVLTELPQD 182

Query: 196 TKVYCGH--EYTLSNSR 240
           T V CGH  E T+   R
Sbjct: 183 TLVICGHYDETTIGQER 199

>Y1663_HAEIN (Q57544) Hypothetical protein HI1663|
          Length = 212

 Score = 39.7 bits (91), Expect = 0.009
 Identities = 34/128 (26%), Positives = 47/128 (36%), Gaps = 3/128 (2%)
 Frame = +1

Query: 10  GHQVLVMETPGHTSGHVSFYFPGSGAIFTGDTLFSLSCGKLF--EGTPEQMYSSLQ-KIV 180
           G    ++  PGHT GH+ F        FTGD LF    G+     G  E + SS++ K++
Sbjct: 121 GFNFEILHLPGHTPGHIGFIEHEKKVAFTGDVLFQGGIGRTDFPRGDYETLISSIRTKLL 180

Query: 181 ALPDVTKVYCGHEYTLSNSRFALSIEPGNEELQEYAASTADLRNKNTPTVPTTIAREKQC 360
            L D   +  GH                                       TTI +EK+ 
Sbjct: 181 PLNDDIIIIAGHGSY------------------------------------TTIGQEKRS 204

Query: 361 NPFLRTSS 384
           NPFL + S
Sbjct: 205 NPFLNSKS 212

>Y888_METJA (Q58298) Hypothetical protein MJ0888|
          Length = 206

 Score = 39.3 bits (90), Expect = 0.011
 Identities = 24/69 (34%), Positives = 39/69 (56%), Gaps = 5/69 (7%)
 Frame = +1

Query: 25  VMETPGHTSGHVSFYFPGSGAIFTGDTLFSLSCGK--LFEGTPEQMYSS---LQKIVALP 189
           ++ TPGHT G +S  +  S  + TGDT+F+   G+  L  G   Q+ +S   L++I    
Sbjct: 124 IIRTPGHTYGSISIIYENS--LITGDTIFAYGVGRWDLPTGDVIQLRNSINLLERIANER 181

Query: 190 DVTKVYCGH 216
           ++ K+Y GH
Sbjct: 182 NIDKLYPGH 190

>Y2612_MYCBO (P64262) Hypothetical protein Mb2612c|
          Length = 224

 Score = 38.5 bits (88), Expect = 0.020
 Identities = 28/77 (36%), Positives = 37/77 (48%), Gaps = 8/77 (10%)
 Frame = +1

Query: 10  GHQVLVMETPGHTSGHVSFYF-----PGSGAIFTGDTLFSLSCGK--LFEGTPEQMYSSL 168
           G  V +  TPGHT G V F            +FTGDTLF  + G+  L  G+   +  S+
Sbjct: 127 GISVNIDHTPGHTRGSVVFRVLQATNNDKDIVFTGDTLFERAIGRTDLAGGSGRDLLRSI 186

Query: 169 -QKIVALPDVTKVYCGH 216
             K++ L D T V  GH
Sbjct: 187 VDKLLVLDDSTVVLPGH 203

>Y2581_MYCTU (P64261) Hypothetical protein Rv2581c/MT2658|
          Length = 224

 Score = 38.5 bits (88), Expect = 0.020
 Identities = 28/77 (36%), Positives = 37/77 (48%), Gaps = 8/77 (10%)
 Frame = +1

Query: 10  GHQVLVMETPGHTSGHVSFYF-----PGSGAIFTGDTLFSLSCGK--LFEGTPEQMYSSL 168
           G  V +  TPGHT G V F            +FTGDTLF  + G+  L  G+   +  S+
Sbjct: 127 GISVNIDHTPGHTRGSVVFRVLQATNNDKDIVFTGDTLFERAIGRTDLAGGSGRDLLRSI 186

Query: 169 -QKIVALPDVTKVYCGH 216
             K++ L D T V  GH
Sbjct: 187 VDKLLVLDDSTVVLPGH 203

>YCBL_ECOLI (P75849) Hypothetical protein ycbL|
          Length = 215

 Score = 36.2 bits (82), Expect = 0.097
 Identities = 22/67 (32%), Positives = 34/67 (50%), Gaps = 3/67 (4%)
 Frame = +1

Query: 25  VMETPGHTSGHVSFYFPGSGAIFTGDTLFSLSCGK--LFEGTPEQMYSSLQ-KIVALPDV 195
           V+  PGHT GHV F+   +  + +GD +F    G+     G   Q+ SS++ K++ L D 
Sbjct: 126 VLHCPGHTPGHVVFFDDRAKLLISGDVIFKGGVGRSDFPRGDHNQLISSIKDKLLPLGDD 185

Query: 196 TKVYCGH 216
                GH
Sbjct: 186 VIFIPGH 192

>FKBP3_DEBHA (Q6BSE7) FK506-binding protein 3 (EC 5.2.1.8) (Peptidyl-prolyl|
           cis-trans isomerase) (PPIase) (Rotamase)
          Length = 437

 Score = 33.1 bits (74), Expect = 0.82
 Identities = 20/56 (35%), Positives = 26/56 (46%)
 Frame = +1

Query: 187 PDVTKVYCGHEYTLSNSRFALSIEPGNEELQEYAASTADLRNKNTPTVPTTIAREK 354
           PD  ++  G EY L +   A  IE   EEL E  A  +  RN   P  PT+   +K
Sbjct: 199 PDEDEIIGGEEYDLDDLEDASDIENKIEELVEEEAQGSKKRNAEEPEAPTSKKSKK 254

>Y1000_PSEAE (P20581) Hypothetical protein PA1000|
          Length = 301

 Score = 33.1 bits (74), Expect = 0.82
 Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 5/73 (6%)
 Frame = +1

Query: 13  HQVLVMETPGHTSGHVSFYFPGSGAIFTGDTL--FSLSCG---KLFEGTPEQMYSSLQKI 177
           H++ V+E  GH+  HV FY      +F GD L  F  + G    L     E    SL+++
Sbjct: 149 HRLQVIEAHGHSDDHVVFYDVRRRRLFCGDALGEFDEAEGVWRPLVFDDMEAYLESLERL 208

Query: 178 VALPDVTKVYCGH 216
             LP + ++  GH
Sbjct: 209 QRLPTLLQLIPGH 221

>ESYN_GIBPU (Q00868) Enniatin synthetase [Includes: N-methylcyclopeptide|
           synthetase (EC 6.3.2.-);
           S-adenosyl-L-methionine-dependent N-methyltransferase
           (EC 2.1.1.-)] (Fragment)
          Length = 983

 Score = 26.9 bits (58), Expect(2) = 1.1
 Identities = 10/30 (33%), Positives = 20/30 (66%)
 Frame = +3

Query: 318 YTNGANNNCEREAVQSFLEDLKSRDKEKAV 407
           +T G NNN  ++ V+  +++L+ R++E  V
Sbjct: 583 HTLGTNNNATKDRVRQKVQELEDREEESLV 612



 Score = 24.3 bits (51), Expect(2) = 1.1
 Identities = 9/37 (24%), Positives = 21/37 (56%)
 Frame = +1

Query: 142 TPEQMYSSLQKIVALPDVTKVYCGHEYTLSNSRFALS 252
           TPE +   +  ++A+P V +++ G   + + +R  L+
Sbjct: 542 TPEYLTEVIDGLIAIPSVKRIFLGDIRSYATNRHFLA 578

>ESYN_FUSEQ (Q00869) Enniatin synthetase [Includes: N-methylcyclopeptide|
            synthetase (EC 6.3.2.-);
            S-adenosyl-L-methionine-dependent N-methyltransferase (EC
            2.1.1.-)]
          Length = 3131

 Score = 26.2 bits (56), Expect(2) = 3.6
 Identities = 9/27 (33%), Positives = 19/27 (70%)
 Frame = +3

Query: 318  YTNGANNNCEREAVQSFLEDLKSRDKE 398
            +T G NNN  ++ V+  +++L+ R++E
Sbjct: 2206 HTLGTNNNATKDRVRQKIQELEDREEE 2232



 Score = 23.1 bits (48), Expect(2) = 3.6
 Identities = 7/24 (29%), Positives = 15/24 (62%)
 Frame = +1

Query: 142  TPEQMYSSLQKIVALPDVTKVYCG 213
            TPE +   +  ++A+P V +++ G
Sbjct: 2165 TPEYLAEVIDGLIAIPSVKRIFLG 2188

>VID28_YEAST (P40547) Vacuolar import and degradation protein VID28|
           (Glucose-induced degradation protein 5)
          Length = 921

 Score = 30.0 bits (66), Expect = 6.9
 Identities = 18/52 (34%), Positives = 27/52 (51%), Gaps = 3/52 (5%)
 Frame = +1

Query: 514 HLFE---KQKWTKNPARPQQKERMEGNVYSLMFLECFGENLSRIVCSLHRVL 660
           +LFE   K+    NP   QQK+ MEG +Y ++ L    EN  ++V     +L
Sbjct: 690 YLFEFLAKKMRLLNPLDTQQKKAMEGILYIIVNLAAVNENKKQLVIEQDEIL 741

>PAK3_MOUSE (Q61036) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)|
           (p21-activated kinase 3) (PAK-3) (Beta-PAK) (CDC42/RAC
           effector kinase PAK-B)
          Length = 559

 Score = 29.6 bits (65), Expect = 9.1
 Identities = 30/101 (29%), Positives = 46/101 (45%), Gaps = 13/101 (12%)
 Frame = +1

Query: 91  FTGDTLFSLSC-GKLFEGTPEQMYSSLQ-----------KIVALPDVTKVYCGHEYTLSN 234
           FT D   S  C GKL EG PEQ    LQ              A+ DV K Y   E T++N
Sbjct: 91  FTPDLYGSQMCPGKLPEGIPEQWARLLQTSNITKLEQKKNPQAVLDVLKFYDSKE-TVNN 149

Query: 235 SRFALSIEPGNEELQEY-AASTADLRNKNTPTVPTTIAREK 354
            ++ +S   G++    Y AA  ++ +  + P +   ++ E+
Sbjct: 150 QKY-MSFTSGDKSAHGYIAAHQSNTKTASEPPLAPPVSEEE 189

>YFLN_BACSU (O34409) Protein yflN|
          Length = 264

 Score = 29.6 bits (65), Expect = 9.1
 Identities = 11/33 (33%), Positives = 18/33 (54%)
 Frame = +1

Query: 34  TPGHTSGHVSFYFPGSGAIFTGDTLFSLSCGKL 132
           TPGHT GH+S +      +  GD + ++   K+
Sbjct: 166 TPGHTPGHISLFRDDGRVLVAGDAVITVEQEKM 198


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 103,644,769
Number of Sequences: 219361
Number of extensions: 2247773
Number of successful extensions: 5744
Number of sequences better than 10.0: 37
Number of HSP's better than 10.0 without gapping: 5537
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5718
length of database: 80,573,946
effective HSP length: 109
effective length of database: 56,663,597
effective search space used: 6856295237
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)