>HDAC1_MOUSE (O09106) Histone deacetylase 1 (HD1)|
          Length = 482

 Score = 35.4 bits (80), Expect = 0.078
 Identities = 23/84 (27%), Positives = 40/84 (47%), Gaps = 1/84 (1%)
 Frame = +3

Query: 66  DDSDLEKSDIFVHCNKRPKVADD-ANADEGGKGNEKGDTGIKKAMVVNLDDEDWLAPPPL 242
           D+ D +K       +KR    ++ +++DE G+G  K  +  KKA  V  +DE    P   
Sbjct: 397 DEEDPDKRISICSSDKRIACEEEFSDSDEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEK 456

Query: 243 KPVLSADVCKDKTMHERLKKQEVQ 314
           K V   +  K++    +  K+EV+
Sbjct: 457 KEVTEEEKTKEEKPEAKGVKEEVK 480

>HDAC1_HUMAN (Q13547) Histone deacetylase 1 (HD1)|
          Length = 482

 Score = 33.9 bits (76), Expect = 0.23
 Identities = 22/84 (26%), Positives = 40/84 (47%), Gaps = 1/84 (1%)
 Frame = +3

Query: 66  DDSDLEKSDIFVHCNKRPKVADD-ANADEGGKGNEKGDTGIKKAMVVNLDDEDWLAPPPL 242
           D+ D +K       +KR    ++ ++++E G+G  K  +  KKA  V  +DE    P   
Sbjct: 397 DEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEK 456

Query: 243 KPVLSADVCKDKTMHERLKKQEVQ 314
           K V   +  K++    +  K+EV+
Sbjct: 457 KEVTEEEKTKEEKPEAKGVKEEVK 480

>THOC1_RAT (P59924) THO complex subunit 1 (Tho1) (Nuclear matrix protein p84)|
           (Liver regeneration-related protein LRRG175)
          Length = 343

 Score = 31.6 bits (70), Expect = 1.1
 Identities = 25/102 (24%), Positives = 43/102 (42%)
 Frame = +3

Query: 66  DDSDLEKSDIFVHCNKRPKVADDANADEGGKGNEKGDTGIKKAMVVNLDDEDWLAPPPLK 245
           +D D E +D  +  N+ P V  D           K  TG +   + N  DE W    P  
Sbjct: 222 EDEDEEDNDALLKENESPDVRQD-----------KPITGERIESLTNKLDEQWKILAPYL 270

Query: 246 PVLSADVCKDKTMHERLKKQEVQKLVDDEFQKVVENVKKDML 371
            +  +D+ + +   E +KK+  Q LV  + Q+ V     +++
Sbjct: 271 EIKDSDIRQIECYSEDMKKRAKQLLVAWKDQEGVHETTDNLI 312

>SDC3_CAEEL (P34706) Zinc finger protein sdc-3|
          Length = 2150

 Score = 31.2 bits (69), Expect = 1.5
 Identities = 13/58 (22%), Positives = 31/58 (53%)
 Frame = +3

Query: 156  KGNEKGDTGIKKAMVVNLDDEDWLAPPPLKPVLSADVCKDKTMHERLKKQEVQKLVDD 329
            +G     T ++  + + ++DE+W+APP +           +   +RL+ ++ Q+++DD
Sbjct: 1692 RGESATVTNLEGPVKIEIEDENWMAPPAITET-------SRKSKKRLRAEKQQQILDD 1742

>MYO2_SACBA (Q876G9) Myosin-2 (Class V unconventional myosin MYO2) (Type V myosin|
            heavy chain MYO2) (Myosin V MYO2)
          Length = 1568

 Score = 30.4 bits (67), Expect = 2.5
 Identities = 15/40 (37%), Positives = 27/40 (67%)
 Frame = +3

Query: 252  LSADVCKDKTMHERLKKQEVQKLVDDEFQKVVENVKKDML 371
            L++ V ++K M ER+K+ +VQ     + Q+ +EN+KK+ L
Sbjct: 956  LASKVKENKEMTERIKELQVQVEESAKLQETLENMKKEHL 995

>MYO2_YEAST (P19524) Myosin-2 (Class V unconventional myosin MYO2) (Type V myosin|
            heavy chain MYO2) (Myosin V MYO2) (Cell divison control
            protein 66)
          Length = 1574

 Score = 30.4 bits (67), Expect = 2.5
 Identities = 15/40 (37%), Positives = 27/40 (67%)
 Frame = +3

Query: 252  LSADVCKDKTMHERLKKQEVQKLVDDEFQKVVENVKKDML 371
            L++ V ++K M ER+K+ +VQ     + Q+ +EN+KK+ L
Sbjct: 954  LASKVKENKEMTERIKELQVQVEESAKLQETLENMKKEHL 993

>NIFD_METTH (O27605) Nitrogenase molybdenum-iron protein alpha chain (EC|
           1.18.6.1) (Nitrogenase component I) (Dinitrogenase)
          Length = 469

 Score = 30.0 bits (66), Expect = 3.3
 Identities = 21/74 (28%), Positives = 38/74 (51%), Gaps = 12/74 (16%)
 Frame = +3

Query: 186 KKAMVVNLDDEDWLAPPPLKPVLSADVCKDKTM------HERLKKQ--EVQKLVDD---- 329
           KK  V +   ++W  P PL+  L  +V    TM      +E++KK+  E   +VDD    
Sbjct: 337 KKVWVFSGGPKNWHLPRPLEDELGMEVVAVSTMFEHEDGYEKIKKRVGENTVIVDDPNSL 396

Query: 330 EFQKVVENVKKDML 371
           E ++++E  + D++
Sbjct: 397 ELEEIIEKYRPDII 410

>SPT6_YEAST (P23615) Transcription initiation protein SPT6|
          Length = 1451

 Score = 30.0 bits (66), Expect = 3.3
 Identities = 19/77 (24%), Positives = 37/77 (48%)
 Frame = +3

Query: 123 VADDANADEGGKGNEKGDTGIKKAMVVNLDDEDWLAPPPLKPVLSADVCKDKTMHERLKK 302
           V D +  DE    +E     +++  +VN DDE+     P        + K +  H+R ++
Sbjct: 36  VFDSSEEDEDIDEDEDEARKVQEGFIVNDDDEN---EDP-----GTSISKKRRKHKRRER 87

Query: 303 QEVQKLVDDEFQKVVEN 353
           +E  +L +D+   ++EN
Sbjct: 88  EEDDRLSEDDLDLLMEN 104

>CWC27_YARLI (Q6CGK4) Peptidyl-prolyl isomerase CWC27 (EC 5.2.1.8)|
          Length = 356

 Score = 30.0 bits (66), Expect = 3.3
 Identities = 29/92 (31%), Positives = 40/92 (43%), Gaps = 4/92 (4%)
 Frame = +3

Query: 120 KVADDANADEGGKGNEKGDTGI----KKAMVVNLDDEDWLAPPPLKPVLSADVCKDKTMH 287
           K   DA AD   + N+ G        K+ + VN DD+D       +PV +          
Sbjct: 172 KAGADAGADAESRENKSGSRDRPKKPKRKLQVNHDDDD-----DEEPVFT---------- 216

Query: 288 ERLKKQEVQKLVDDEFQKVVENVKKDMLAKKP 383
               K+ V KLV+D+F+K   NV     AKKP
Sbjct: 217 ----KKSVSKLVEDKFKKDNTNV-----AKKP 239

>DNM3B_MOUSE (O88509) DNA (cytosine-5)-methyltransferase 3B (EC 2.1.1.37)|
           (Dnmt3b) (DNA methyltransferase MmuIIIB) (DNA MTase
           MmuIIIB) (M.MmuIIIB)
          Length = 859

 Score = 30.0 bits (66), Expect = 3.3
 Identities = 19/65 (29%), Positives = 34/65 (52%), Gaps = 11/65 (16%)
 Frame = +3

Query: 165 EKGDTGIKKAMVVN-------LDDEDWLAPPPLKPVLSADVCKDKT----MHERLKKQEV 311
           E+G +G ++ ++VN        D +D  +PP L+ + +  VC  +T       RL K+EV
Sbjct: 11  EEGASGYEECIIVNGNFSDQSSDTKDAPSPPVLEAICTEPVCTPETRGRRSSSRLSKREV 70

Query: 312 QKLVD 326
             L++
Sbjct: 71  SSLLN 75

>TOP1_METJA (Q59046) DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)|
           (Omega-protein) (Relaxing enzyme) (Untwisting enzyme)
           (Swivelase)
          Length = 761

 Score = 29.6 bits (65), Expect = 4.3
 Identities = 21/60 (35%), Positives = 30/60 (50%)
 Frame = +3

Query: 222 WLAPPPLKPVLSADVCKDKTMHERLKKQEVQKLVDDEFQKVVENVKKDMLAKKPPEPIVL 401
           W+    LK  L A   K+K  +E+  K   +K+ D++  KVVE +KK     KP  P  L
Sbjct: 224 WVIEALLKDNLKAIHEKEKFWNEKEAKNVYEKIKDEKSAKVVE-IKKTKRKLKPLPPFDL 282

>KTN1_CHICK (Q90631) Kinectin|
          Length = 1364

 Score = 29.6 bits (65), Expect = 4.3
 Identities = 31/127 (24%), Positives = 49/127 (38%)
 Frame = +3

Query: 15  EPLFDYSRVQPTIDFCFDDSDLEKSDIFVHCNKRPKVADDANADEGGKGNEKGDTGIKKA 194
           E L+D    +   D  F  +  +K       NK+ K A + N  E    +   D  +  A
Sbjct: 31  ETLYDEVLAKQKRDLKFPPTKSDKKKTEKKKNKK-KEAQNGNIHESDSESTPRDFKLSDA 89

Query: 195 MVVNLDDEDWLAPPPLKPVLSADVCKDKTMHERLKKQEVQKLVDDEFQKVVENVKKDMLA 374
           +     DE+ +AP PL    ++       + ER KK++ QK   D+         K    
Sbjct: 90  LGT---DEEQVAPVPLSATEAS-----AGIRERKKKEKKQKAAQDDHVTKESEGSKSSGK 141

Query: 375 KKPPEPI 395
           K  P P+
Sbjct: 142 KVEPVPV 148

>UVRB_STAHJ (Q4L4I5) UvrABC system protein B (Protein uvrB) (Excinuclease ABC|
           subunit B)
          Length = 661

 Score = 29.6 bits (65), Expect = 4.3
 Identities = 15/40 (37%), Positives = 27/40 (67%)
 Frame = +3

Query: 249 VLSADVCKDKTMHERLKKQEVQKLVDDEFQKVVENVKKDM 368
           V+SA V  D+T +E+ + +  +K+   E QK +EN++K+M
Sbjct: 597 VISATVDNDET-NEKQQTELPKKMTKKERQKTIENIEKEM 635

>VPS27_YEAST (P40343) Vacuolar protein sorting-associated protein VPS27|
          Length = 622

 Score = 29.3 bits (64), Expect = 5.6
 Identities = 26/114 (22%), Positives = 50/114 (43%), Gaps = 3/114 (2%)
 Frame = +3

Query: 18  PLFDYSRVQPT--IDFCFDDSDLEKSDIFVHCNKRPKVADDANADEGGKGNEKGDTGIKK 191
           PL D    +P    D CF+D DL++ D      K  K       D      E  +  I+K
Sbjct: 209 PLPDLGIYEPVRVCDSCFEDYDLKRHD---DSKKSKKHRHKRKKDRDYSTPEDEEELIRK 265

Query: 192 AMVVNL-DDEDWLAPPPLKPVLSADVCKDKTMHERLKKQEVQKLVDDEFQKVVE 350
           A+ ++L +  +  +  P+ PV+ +           +K+QE+++  D + +  ++
Sbjct: 266 AIELSLKESRNSASSEPIVPVVES--------KNEVKRQEIEEEEDPDLKAAIQ 311

>MPP10_YEAST (P47083) U3 small nucleolar ribonucleoprotein protein MPP10|
          Length = 593

 Score = 29.3 bits (64), Expect = 5.6
 Identities = 29/112 (25%), Positives = 49/112 (43%), Gaps = 6/112 (5%)
 Frame = +3

Query: 75  DLEKSDIFVHCNKRPKVADDANADEGGKGNEKGDTGIKKAMVVNLDDE------DWLAPP 236
           DLEK       N+    A+D+N  E  +G+E  D    + M  + ++E      D+   P
Sbjct: 189 DLEKF------NRDTLAAEDSN--EASEGSEDEDIDYFQDMPSDDEEEEAIYYEDFFDKP 240

Query: 237 PLKPVLSADVCKDKTMHERLKKQEVQKLVDDEFQKVVENVKKDMLAKKPPEP 392
             +PV      KD         +E ++L ++E    ++ VK D+ A +  EP
Sbjct: 241 TKEPVKKHSDVKD--------PKEDEELDEEEHDSAMDKVKLDLFADEEDEP 284

>ERCC5_XENLA (P14629) DNA-repair protein complementing XP-G cells homolog|
            (Xeroderma pigmentosum group G-complementing protein
            homolog)
          Length = 1196

 Score = 29.3 bits (64), Expect = 5.6
 Identities = 17/58 (29%), Positives = 26/58 (44%)
 Frame = +3

Query: 132  DANADEGGKGNEKGDTGIKKAMVVNLDDEDWLAPPPLKPVLSADVCKDKTMHERLKKQ 305
            D  +  G  G +K    ++ +   + DDED       KPV      K KTM E +K++
Sbjct: 1141 DKQSQSGIVGRQKASNKVESSS--SSDDEDRTVMVTAKPVFQGKKTKSKTMKETVKRK 1196

>PHF2_HUMAN (O75151) PHD finger protein 2 (GRC5)|
          Length = 1101

 Score = 28.9 bits (63), Expect = 7.3
 Identities = 18/47 (38%), Positives = 23/47 (48%), Gaps = 8/47 (17%)
 Frame = +3

Query: 21  LFDYSRVQPTIDFCFDDSDL--------EKSDIFVHCNKRPKVADDA 137
           L DY   Q  +D CF DSD         E + IF   +K+ K +DDA
Sbjct: 856 LDDYEEEQDHLDACFKDSDYVYPSLESDEDNPIFKSRSKKRKGSDDA 902

>ASPM_CANFA (P62286) Abnormal spindle-like microcephaly-associated protein|
           homolog (Fragment)
          Length = 3452

 Score = 28.9 bits (63), Expect = 7.3
 Identities = 16/48 (33%), Positives = 26/48 (54%), Gaps = 8/48 (16%)
 Frame = +3

Query: 243 KPVLSADVCKDKTMHERLKKQEVQK--------LVDDEFQKVVENVKK 362
           +P+LSA + K K+   R  ++E  K         V  EF+KV +N+K+
Sbjct: 484 RPILSATITKRKSNFTRENQKETNKPKAKRCLNSVAGEFEKVTDNIKE 531

>NAC_METJA (Q57728) Nascent polypeptide-associated complex protein|
          Length = 128

 Score = 28.5 bits (62), Expect = 9.6
 Identities = 18/62 (29%), Positives = 32/62 (51%)
 Frame = +3

Query: 159 GNEKGDTGIKKAMVVNLDDEDWLAPPPLKPVLSADVCKDKTMHERLKKQEVQKLVDDEFQ 338
           G E  D  ++K + V  DDE+W+   P   V+     K  ++  + KK + +K+ ++E  
Sbjct: 22  GMETEDLDVRKVIFV-FDDEEWVFEEPKVQVMDILGVKTYSITGKPKKIKKEKVEEEEEV 80

Query: 339 KV 344
           KV
Sbjct: 81  KV 82

>Y06P_BPT4 (P39223) Hypothetical 23.8 kDa protein in e-segB intergenic region|
          Length = 202

 Score = 28.5 bits (62), Expect = 9.6
 Identities = 16/44 (36%), Positives = 25/44 (56%), Gaps = 5/44 (11%)
 Frame = +3

Query: 264 VCKDKTMHER---LKKQEVQKLVDDEFQKVVE--NVKKDMLAKK 380
           +   +T HE    L K+ +  +VDD F K+VE  N + D+L +K
Sbjct: 142 IVDSETKHENKRILSKRNILNIVDDLFDKLVENPNFESDLLLEK 185

>SYT_THETN (Q8R9A4) Threonyl-tRNA synthetase (EC 6.1.1.3) (Threonine--tRNA|
           ligase) (ThrRS)
          Length = 644

 Score = 28.5 bits (62), Expect = 9.6
 Identities = 17/63 (26%), Positives = 34/63 (53%), Gaps = 2/63 (3%)
 Frame = +3

Query: 222 WLAPPPLK--PVLSADVCKDKTMHERLKKQEVQKLVDDEFQKVVENVKKDMLAKKPPEPI 395
           WLAP  ++  P+        + ++ERL++ +++  +DD  +K+   +++  L K P   I
Sbjct: 543 WLAPVQVRVLPISEKHHEYARKVYERLQEHDIRVELDDRNEKIGYKIREAQLQKIPYMLI 602

Query: 396 VLD 404
           V D
Sbjct: 603 VGD 605

>TBP7_YEAST (P40340) TAT-binding homolog 7|
          Length = 1379

 Score = 28.5 bits (62), Expect = 9.6
 Identities = 26/113 (23%), Positives = 46/113 (40%)
 Frame = +3

Query: 27  DYSRVQPTIDFCFDDSDLEKSDIFVHCNKRPKVADDANADEGGKGNEKGDTGIKKAMVVN 206
           +Y+ ++   DF  DD  ++K +  V          D  +DE    N+KGD          
Sbjct: 45  NYAEIEKVFDFLEDDQVMDKDETPV----------DVTSDEHHNNNQKGDD--------E 86

Query: 207 LDDEDWLAPPPLKPVLSADVCKDKTMHERLKKQEVQKLVDDEFQKVVENVKKD 365
            DD D ++P       +A   ++ T    L+K++     +D+     E+V  D
Sbjct: 87  DDDVDLVSPHE-----NARTNEELTNERNLRKRKAHDPEEDDESFHEEDVDDD 134

>LRRC6_HUMAN (Q86X45) Leucine-rich repeat-containing protein 6 (Leucine-rich|
           testis-specific protein) (Testis-specific leucine-rich
           repeat protein)
          Length = 466

 Score = 28.5 bits (62), Expect = 9.6
 Identities = 34/163 (20%), Positives = 67/163 (41%), Gaps = 29/163 (17%)
 Frame = +3

Query: 3   SEELEPLFDYSRVQPTIDFCFDDSDLEKSDIFVHCNKRPKVADDA---NADEGGKGNEKG 173
           SE ++ L DYS ++P I       + EK     HC KR K+ ++A   + +E    +++ 
Sbjct: 153 SERIKALQDYSVIEPQI------REQEKD----HCLKRAKLKEEAQRKHQEEDKNEDKRS 202

Query: 174 DTGIK-------KAMVVNLDDEDWLAPPPL-------------------KPVLSADVCKD 275
           + G          A + +L+ +D L  P +                   KP L     + 
Sbjct: 203 NAGFDGRWYTDINATLSSLESKDHLQAPDIEEHNTKKLDNSEDDLEFWNKPCLFTPESRL 262

Query: 276 KTMHERLKKQEVQKLVDDEFQKVVENVKKDMLAKKPPEPIVLD 404
           +T+    K+++ Q+ + ++ +KV           KPP  ++ +
Sbjct: 263 ETLRHMEKQRKKQEKLSEKKKKV-----------KPPRTLITE 294

>SYT_RHOBA (Q7UJ52) Threonyl-tRNA synthetase (EC 6.1.1.3) (Threonine--tRNA|
           ligase) (ThrRS)
          Length = 743

 Score = 28.5 bits (62), Expect = 9.6
 Identities = 12/31 (38%), Positives = 21/31 (67%)
 Frame = +3

Query: 312 QKLVDDEFQKVVENVKKDMLAKKPPEPIVLD 404
           +K+ +D+F K+   +KK + AK+P E  VL+
Sbjct: 131 EKISEDDFPKIEAEIKKIIKAKEPFERFVLE 161


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,750,591
Number of Sequences: 219361
Number of extensions: 788851
Number of successful extensions: 3309
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 3220
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3301
length of database: 80,573,946
effective HSP length: 103
effective length of database: 57,979,763
effective search space used: 3246866728
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)