ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bah60j04 |
|---|---|
| Clone Library Name | barley_pub |
>4CL1_ORYSA (P17814) 4-coumarate--CoA ligase 1 (EC 6.2.1.12) (4CL 1)| (4-coumaroyl-CoA synthase 1) Length = 564 Score = 353 bits (906), Expect = 3e-97 Identities = 165/222 (74%), Positives = 197/222 (88%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGVMLTHRSL TSVAQQVDGENPN+ DV+LC LP+FHIYSLN++++ GLR G+A+V Sbjct: 217 KGVMLTHRSLSTSVAQQVDGENPNIGLHAGDVILCALPMFHIYSLNTIMMCGLRVGAAIV 276 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKEL 362 +MR+FD+ A+++LV H +T+AP VPPIVV +AKS A DL+S+RMV+SGAAPMGK++ Sbjct: 277 VMRRFDLAAMMDLVERHRVTIAPLVPPIVVAVAKSEAAAARDLSSVRMVLSGAAPMGKDI 336 Query: 363 QDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDT 542 +DAFMAK+P AVLGQGYGMTEAGPVL+MCLAFAKEPFKVKSG+CGTVVRNA LKI+DPDT Sbjct: 337 EDAFMAKLPGAVLGQGYGMTEAGPVLSMCLAFAKEPFKVKSGACGTVVRNAELKIIDPDT 396 Query: 543 GASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 G SLGRN PGEICIRG+QIMKGYLN+PE+TKNTID +GWLHT Sbjct: 397 GKSLGRNLPGEICIRGQQIMKGYLNNPEATKNTIDAEGWLHT 438
>4CL1_TOBAC (O24145) 4-coumarate--CoA ligase 1 (EC 6.2.1.12) (4CL 1)| (4-coumaroyl-CoA synthase 1) Length = 547 Score = 347 bits (891), Expect = 1e-95 Identities = 165/222 (74%), Positives = 193/222 (86%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGVMLTH+ L+TSVAQQVDGEN NLY EDVL+C+LPLFHIYSLNS+LL GLR G+A++ Sbjct: 202 KGVMLTHKGLVTSVAQQVDGENANLYMHSEDVLMCVLPLFHIYSLNSILLCGLRVGAAIL 261 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKEL 362 IM+KFDI +EL++ + +++ PFVPPIV+ IAKSP V + DL+S+R VMSGAAP+GKEL Sbjct: 262 IMQKFDIAPFLELIQKYKVSIGPFVPPIVLAIAKSPIVDSYDLSSVRTVMSGAAPLGKEL 321 Query: 363 QDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDT 542 +DA K PNA LGQGYGMTEAGPVLAMCLAFAKEPF +KSG+CGTVVRNA +KIVDPDT Sbjct: 322 EDAVRTKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPFDIKSGACGTVVRNAEMKIVDPDT 381 Query: 543 GASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 G SL RNQPGEICIRG+QIMKGYLNDPE+T TIDK+GWLHT Sbjct: 382 GCSLPRNQPGEICIRGDQIMKGYLNDPEATTRTIDKEGWLHT 423
>4CL1_SOLTU (P31684) 4-coumarate--CoA ligase 1 (EC 6.2.1.12) (4CL 1)| (4-coumaroyl-CoA synthase 1) Length = 545 Score = 346 bits (888), Expect = 3e-95 Identities = 166/222 (74%), Positives = 191/222 (86%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGVMLTH+ L+TSVAQQVDGEN NLY +DVL+C+LPLFHIYSLNSVLL LR G+A++ Sbjct: 200 KGVMLTHKGLVTSVAQQVDGENANLYMHSDDVLMCVLPLFHIYSLNSVLLCALRVGAAIL 259 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKEL 362 IM+KFDI +EL+ H +T+ PFVPPIV+ IAKSP V DL+S+R VMSGAAP+GKEL Sbjct: 260 IMQKFDIAQFLELIPKHKVTIGPFVPPIVLAIAKSPLVDNYDLSSVRTVMSGAAPLGKEL 319 Query: 363 QDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDT 542 +DA AK PNA LGQGYGMTEAGPVLAMCLAFAKEPF +KSG+CGTVVRNA +KIVDPDT Sbjct: 320 EDAVRAKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPFDIKSGACGTVVRNAEMKIVDPDT 379 Query: 543 GASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 G SL RNQPGEICIRG+QIMKGYLNDPE+T TI+K+GWLHT Sbjct: 380 GCSLPRNQPGEICIRGDQIMKGYLNDPEATARTIEKEGWLHT 421
>4CL2_SOLTU (P31685) 4-coumarate--CoA ligase 2 (EC 6.2.1.12) (4CL 2)| (4-coumaroyl-CoA synthase 2) Length = 545 Score = 346 bits (887), Expect = 4e-95 Identities = 166/222 (74%), Positives = 191/222 (86%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGVMLTH+ L+TSVAQQVDGEN NLY +DVL+C+LPLFHIYSLNSVLL LR G+A++ Sbjct: 200 KGVMLTHKGLVTSVAQQVDGENANLYMHSDDVLMCVLPLFHIYSLNSVLLCALRVGAAIL 259 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKEL 362 IM+KFDI +EL+ H +T+ PFVPPIV+ IAKSP V DL+S+R VMSGAAP+GKEL Sbjct: 260 IMQKFDIAQFLELIPKHKVTIGPFVPPIVLAIAKSPLVHNYDLSSVRTVMSGAAPLGKEL 319 Query: 363 QDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDT 542 +DA AK PNA LGQGYGMTEAGPVLAMCLAFAKEPF +KSG+CGTVVRNA +KIVDPDT Sbjct: 320 EDAVRAKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPFDIKSGACGTVVRNAEMKIVDPDT 379 Query: 543 GASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 G SL RNQPGEICIRG+QIMKGYLNDPE+T TI+K+GWLHT Sbjct: 380 GCSLPRNQPGEICIRGDQIMKGYLNDPEATARTIEKEGWLHT 421
>4CL_VANPL (O24540) 4-coumarate--CoA ligase (EC 6.2.1.12) (4CL)| (4-coumaroyl-CoA synthase) Length = 553 Score = 345 bits (885), Expect = 7e-95 Identities = 166/222 (74%), Positives = 193/222 (86%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGVMLTH+ L+TSVAQQVDGENPNLY +DVLLC+LPLFHIYSLNSVLL GLRAGS ++ Sbjct: 206 KGVMLTHKGLVTSVAQQVDGENPNLYMHSDDVLLCVLPLFHIYSLNSVLLCGLRAGSGIL 265 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKEL 362 IM+KF+I +EL++ + +T+ PFVPPIV+ IAKS V DL+S+R VMSGAAP+GKEL Sbjct: 266 IMQKFEIVPFLELIQKYKVTIGPFVPPIVLAIAKSTVVDNYDLSSVRTVMSGAAPLGKEL 325 Query: 363 QDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDT 542 +DA AK PNA LGQGYGMTEAGPVLAMCLAFAKEPF +KSG+CGTVVRNA +KIVDP+T Sbjct: 326 EDAVRAKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPFDIKSGACGTVVRNAEMKIVDPET 385 Query: 543 GASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 G+SL RN PGEICIRG+QIMKGYLNDPE+T TIDK+GWLHT Sbjct: 386 GSSLPRNHPGEICIRGDQIMKGYLNDPEATARTIDKEGWLHT 427
>4CL2_TOBAC (O24146) 4-coumarate--CoA ligase 2 (EC 6.2.1.12) (4CL 2)| (4-coumaroyl-CoA synthase 2) Length = 542 Score = 344 bits (882), Expect = 2e-94 Identities = 165/222 (74%), Positives = 193/222 (86%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGVMLTH+ L+TSVAQQVDGENPNLY EDV+LC+LPLFHIYSLNSVLL GLR G+A++ Sbjct: 197 KGVMLTHKGLVTSVAQQVDGENPNLYIHSEDVMLCVLPLFHIYSLNSVLLCGLRVGAAIL 256 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKEL 362 IM+KFDI + +EL++ + +T+ PFVPPIV+ IAKSP V DL+S+R VMSGAAP+GKEL Sbjct: 257 IMQKFDIVSFLELIQRYKVTIGPFVPPIVLAIAKSPMVDDYDLSSVRTVMSGAAPLGKEL 316 Query: 363 QDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDT 542 +D AK PNA LGQGYGMTEAGPVLAMCLAFAKEPF++KSG+CGTVVRNA +KIVDP T Sbjct: 317 EDTVRAKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVDPKT 376 Query: 543 GASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 G SL RNQ GEICIRG+QIMKGYLNDPE+T TIDK+GWL+T Sbjct: 377 GNSLPRNQSGEICIRGDQIMKGYLNDPEATARTIDKEGWLYT 418
>4CL2_PETCR (P14913) 4-coumarate--CoA ligase 1 (EC 6.2.1.12) (4CL 1)| (4-coumaroyl-CoA synthase 1) Length = 544 Score = 341 bits (875), Expect = 1e-93 Identities = 162/222 (72%), Positives = 193/222 (86%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGVMLTH+ L+TSVAQQVDG+NPNLY EDV++C+LPLFHIYSLN+VL GLRAG ++ Sbjct: 198 KGVMLTHKGLVTSVAQQVDGDNPNLYMHSEDVMICILPLFHIYSLNAVLCCGLRAGVTIL 257 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKEL 362 IM+KFDI +EL++ + +T+ PFVPPIV+ IAKSP V DL+S+R VMSGAAP+GKEL Sbjct: 258 IMQKFDIVPFLELIQKYKVTIGPFVPPIVLAIAKSPVVDKYDLSSVRTVMSGAAPLGKEL 317 Query: 363 QDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDT 542 +DA AK PNA LGQGYGMTEAGPVLAMCLAFAKEP+++KSG+CGTVVRNA +KIVDP+T Sbjct: 318 EDAVRAKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPYEIKSGACGTVVRNAEMKIVDPET 377 Query: 543 GASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 ASL RNQ GEICIRG+QIMKGYLNDPEST+ TID++GWLHT Sbjct: 378 NASLPRNQRGEICIRGDQIMKGYLNDPESTRTTIDEEGWLHT 419
>4CL1_PETCR (P14912) 4-coumarate--CoA ligase 1 (EC 6.2.1.12) (4CL 1)| (4-coumaroyl-CoA synthase 1) Length = 544 Score = 341 bits (875), Expect = 1e-93 Identities = 162/222 (72%), Positives = 193/222 (86%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGVMLTH+ L+TSVAQQVDG+NPNLY EDV++C+LPLFHIYSLN+VL GLRAG ++ Sbjct: 198 KGVMLTHKGLVTSVAQQVDGDNPNLYMHSEDVMICILPLFHIYSLNAVLCCGLRAGVTIL 257 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKEL 362 IM+KFDI +EL++ + +T+ PFVPPIV+ IAKSP V DL+S+R VMSGAAP+GKEL Sbjct: 258 IMQKFDIVPFLELIQKYKVTIGPFVPPIVLAIAKSPVVDKYDLSSVRTVMSGAAPLGKEL 317 Query: 363 QDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDT 542 +DA AK PNA LGQGYGMTEAGPVLAMCLAFAKEP+++KSG+CGTVVRNA +KIVDP+T Sbjct: 318 EDAVRAKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPYEIKSGACGTVVRNAEMKIVDPET 377 Query: 543 GASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 ASL RNQ GEICIRG+QIMKGYLNDPEST+ TID++GWLHT Sbjct: 378 NASLPRNQRGEICIRGDQIMKGYLNDPESTRTTIDEEGWLHT 419
>4CL1_ARATH (Q42524) 4-coumarate--CoA ligase 1 (EC 6.2.1.12) (4CL 1) (At4CL1)| (4-coumaroyl-CoA synthase 1) Length = 561 Score = 335 bits (859), Expect = 7e-92 Identities = 162/222 (72%), Positives = 189/222 (85%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGVMLTH+ L+TSVAQQVDGENPNLYF +DV+LC+LP+FHIY+LNS++L GLR G+A++ Sbjct: 218 KGVMLTHKGLVTSVAQQVDGENPNLYFHSDDVILCVLPMFHIYALNSIMLCGLRVGAAIL 277 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKEL 362 IM KF+I L+EL++ +TVAP VPPIV+ IAKS + DL+SIR+V SGAAP+GKEL Sbjct: 278 IMPKFEINLLLELIQRCKVTVAPMVPPIVLAIAKSSETEKYDLSSIRVVKSGAAPLGKEL 337 Query: 363 QDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDT 542 +DA AK PNA LGQGYGMTEAGPVLAM L FAKEPF VKSG+CGTVVRNA +KIVDPDT Sbjct: 338 EDAVNAKFPNAKLGQGYGMTEAGPVLAMSLGFAKEPFPVKSGACGTVVRNAEMKIVDPDT 397 Query: 543 GASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 G SL RNQPGEICIRG QIMKGYLN+P +T TIDKDGWLHT Sbjct: 398 GDSLSRNQPGEICIRGHQIMKGYLNNPAATAETIDKDGWLHT 439
>4CL2_SOYBN (P31687) 4-coumarate--CoA ligase 2 (EC 6.2.1.12) (4CL 2)| (4-coumaroyl-CoA synthase 2) (Clone 4CL16) Length = 562 Score = 332 bits (852), Expect = 5e-91 Identities = 158/222 (71%), Positives = 193/222 (86%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV+LTH+SL TSVAQQVDGENPNLY EDVLLC+LPLFHI+SLNSVLL LRAGSA++ Sbjct: 215 KGVILTHKSLTTSVAQQVDGENPNLYLTTEDVLLCVLPLFHIFSLNSVLLCALRAGSAVL 274 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKEL 362 +M+KF+IG L+EL++ H ++VA VPP+V+ +AK+P V DL+SIR+V+SGAAP+GKEL Sbjct: 275 LMQKFEIGTLLELIQRHRVSVAMVVPPLVLALAKNPMVADFDLSSIRLVLSGAAPLGKEL 334 Query: 363 QDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDT 542 ++A ++P AVLGQGYGMTEAGPVL+MCL FAK+PF+ KSGSCGTVVRNA LK+VDP+T Sbjct: 335 EEALRNRMPQAVLGQGYGMTEAGPVLSMCLGFAKQPFQTKSGSCGTVVRNAELKVVDPET 394 Query: 543 GASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 G SLG NQPGEICIRG+QIMKGYLND +T +TID +GWLHT Sbjct: 395 GRSLGYNQPGEICIRGQQIMKGYLNDEAATASTIDSEGWLHT 436
>4CL2_ARATH (Q9S725) 4-coumarate--CoA ligase 2 (EC 6.2.1.12) (4CL 2) (At4Cl2)| (4-coumaroyl-CoA synthase 2) Length = 556 Score = 325 bits (834), Expect = 6e-89 Identities = 157/222 (70%), Positives = 187/222 (84%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGVMLTH+ L+TSVAQQVDGENPNLYF ++DV+LC+ P+FHIY+LNS++L LR G+ ++ Sbjct: 211 KGVMLTHKGLVTSVAQQVDGENPNLYFNRDDVILCVWPMFHIYALNSIMLCSLRIGATIL 270 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKEL 362 IM KF+I L+E ++ +TVA VPPIV+ IAKSP+ DL+S+RMV SGAAP+GKEL Sbjct: 271 IMPKFEITLLLEQIQRCKVTVAMVVPPIVLAIAKSPETEKYDLSSVRMVKSGAAPLGKEL 330 Query: 363 QDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDT 542 +DA AK PNA LGQGYGMTEAGPVLAM L FAKEPF VKSG+CGTVVRNA +KI+DPDT Sbjct: 331 EDAISAKFPNAKLGQGYGMTEAGPVLAMSLGFAKEPFPVKSGACGTVVRNAEMKILDPDT 390 Query: 543 GASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 G SL RN+PGEICIRG QIMKGYLNDP +T +TIDKDGWLHT Sbjct: 391 GDSLPRNKPGEICIRGNQIMKGYLNDPLATASTIDKDGWLHT 432
>4CL_PINTA (P41636) 4-coumarate--CoA ligase (EC 6.2.1.12) (4CL)| (4-coumaroyl-CoA synthase) Length = 537 Score = 322 bits (825), Expect = 6e-88 Identities = 153/222 (68%), Positives = 188/222 (84%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGVMLTH+ L++SVAQQVDGENPNLYF +DV+LC+LPLFHIYSLNSVLL LRAG+A + Sbjct: 197 KGVMLTHKGLVSSVAQQVDGENPNLYFHSDDVILCVLPLFHIYSLNSVLLCALRAGAATL 256 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKEL 362 IM+KF++ +EL++ + +TVAP VPPIV++I KSP V+ D++S+R++MSGAAP+GKEL Sbjct: 257 IMQKFNLTTCLELIQKYKVTVAPIVPPIVLDITKSPIVSQYDVSSVRIIMSGAAPLGKEL 316 Query: 363 QDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDT 542 +DA + P A+ GQGYGMTEAGPVLAM LAFAK PF VKSGSCGTVVRNA +KI+D +T Sbjct: 317 EDALRERFPKAIFGQGYGMTEAGPVLAMNLAFAKNPFPVKSGSCGTVVRNAQIKILDTET 376 Query: 543 GASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 G SL NQ GEICIRG +IMKGY+NDPEST TID++GWLHT Sbjct: 377 GESLPHNQAGEICIRGPEIMKGYINDPESTAATIDEEGWLHT 418
>4CL3_ARATH (Q9S777) 4-coumarate--CoA ligase 3 (EC 6.2.1.12) (4CL 3) (At4CL3)| (4-coumaroyl-CoA synthase 3) Length = 561 Score = 320 bits (819), Expect = 3e-87 Identities = 150/222 (67%), Positives = 188/222 (84%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV+LTH+SLITSVAQQVDG+NPNLY + DV+LC+LPLFHIYSLNSVLL LR+G+ ++ Sbjct: 221 KGVVLTHKSLITSVAQQVDGDNPNLYLKSNDVILCVLPLFHIYSLNSVLLNSLRSGATVL 280 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKEL 362 +M KF+IGAL++L++ H +T+A VPP+V+ +AK+P V + DL+S+R V+SGAAP+GKEL Sbjct: 281 LMHKFEIGALLDLIQRHRVTIAALVPPLVIALAKNPTVNSYDLSSVRFVLSGAAPLGKEL 340 Query: 363 QDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDT 542 QD+ ++P A+LGQGYGMTEAGPVL+M L FAKEP KSGSCGTVVRNA LK+V +T Sbjct: 341 QDSLRRRLPQAILGQGYGMTEAGPVLSMSLGFAKEPIPTKSGSCGTVVRNAELKVVHLET 400 Query: 543 GASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 SLG NQPGEICIRG+QIMK YLNDPE+T TID++GWLHT Sbjct: 401 RLSLGYNQPGEICIRGQQIMKEYLNDPEATSATIDEEGWLHT 442
>4CL2_ORYSA (Q42982) 4-coumarate--CoA ligase 2 (EC 6.2.1.12) (4CL 2)| (4-coumaroyl-CoA synthase 2) Length = 569 Score = 312 bits (800), Expect = 5e-85 Identities = 150/222 (67%), Positives = 184/222 (82%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV+LTHRS+++ VAQQVDGENPNL+ DV LC+LPLFHI+SLNSVLL +RAG+A+ Sbjct: 227 KGVVLTHRSVVSGVAQQVDGENPNLHMGAGDVALCVLPLFHIFSLNSVLLCAVRAGAAVA 286 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKEL 362 +M +F++GA++ + +TVA VPP+V+ +AK+P V DL+SIR+V+SGAAP+GKEL Sbjct: 287 LMPRFEMGAMLGAIERWRVTVAAVVPPLVLALAKNPFVERHDLSSIRIVLSGAAPLGKEL 346 Query: 363 QDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDT 542 +DA A++P A+ GQGYGMTEAGPVL+MC AFAKEP KSGSCGTVVRNA LK+VDPDT Sbjct: 347 EDALRARLPQAIFGQGYGMTEAGPVLSMCPAFAKEPTPAKSGSCGTVVRNAELKVVDPDT 406 Query: 543 GASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 G SLGRN PGEICIRG QIMKGYLNDPE+T TID +GWLHT Sbjct: 407 GFSLGRNLPGEICIRGPQIMKGYLNDPEATAATIDVEGWLHT 448
>4CL4_ARATH (Q9LU36) 4-coumarate--CoA ligase 4 (EC 6.2.1.12) (4CL 4) (At4CL4)| (4-coumaroyl-CoA synthase 4) (4-coumarate CoA ligase isoform 5) Length = 570 Score = 286 bits (733), Expect = 3e-77 Identities = 130/222 (58%), Positives = 178/222 (80%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGVM+TH+ L+TS+AQ+VDGENPNL F DV+LC LP+FHIY+L++++L+ +R G+A++ Sbjct: 226 KGVMITHKGLVTSIAQKVDGENPNLNFTANDVILCFLPMFHIYALDALMLSAMRTGAALL 285 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKEL 362 I+ +F++ ++EL++ + +TV P PP+V+ KSP+ DL+S+R+++SGAA + KEL Sbjct: 286 IVPRFELNLVMELIQRYKVTVVPVAPPVVLAFIKSPETERYDLSSVRIMLSGAATLKKEL 345 Query: 363 QDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDT 542 +DA K PNA+ GQGYGMTE+G V A LAFAK PFK KSG+CGTV+RNA +K+VD +T Sbjct: 346 EDAVRLKFPNAIFGQGYGMTESGTV-AKSLAFAKNPFKTKSGACGTVIRNAEMKVVDTET 404 Query: 543 GASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 G SL RN+ GEIC+RG Q+MKGYLNDPE+T TIDKDGWLHT Sbjct: 405 GISLPRNKSGEICVRGHQLMKGYLNDPEATARTIDKDGWLHT 446
>4CL1_SOYBN (P31686) 4-coumarate--CoA ligase 1 (EC 6.2.1.12) (4CL 1)| (4-coumaroyl-CoA synthase 1) (Clone 4CL14) (Fragment) Length = 293 Score = 234 bits (597), Expect = 2e-61 Identities = 113/168 (67%), Positives = 136/168 (80%) Frame = +3 Query: 165 AGSAMVIMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAA 344 A + +++M KFDI +L+ L+ H +T+AP VPPIV+ I+KSP + DL+SIR++ SG A Sbjct: 1 AKATILLMPKFDINSLLALIHKHKVTIAPVVPPIVLAISKSPDLHKYDLSSIRVLKSGGA 60 Query: 345 PMGKELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLK 524 P+GKEL+D AK PNA LGQGYGMTEAGPVL M LAFAKEP VK G+CGTVVRNA +K Sbjct: 61 PLGKELEDTLRAKFPNAKLGQGYGMTEAGPVLTMSLAFAKEPIDVKPGACGTVVRNAEMK 120 Query: 525 IVDPDTGASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 IVDP+TG SL RNQ GEICIRG+QIMKGYLND E+T+ TIDKDGWLHT Sbjct: 121 IVDPETGHSLPRNQSGEICIRGDQIMKGYLNDGEATERTIDKDGWLHT 168
>LUCI_PHOPY (P08659) Luciferin 4-monooxygenase (EC 1.13.12.7) (Luciferase)| Length = 550 Score = 119 bits (299), Expect = 6e-27 Identities = 75/222 (33%), Positives = 116/222 (52%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV L HR+ + D N + +L ++P H + + + L L G +V Sbjct: 206 KGVALPHRTACVRFSHARDPIFGNQII-PDTAILSVVPFHHGFGMFTTL-GYLICGFRVV 263 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKEL 362 +M +F+ + ++ + I A VP + AKS + DL+++ + SG AP+ KE+ Sbjct: 264 LMYRFEEELFLRSLQDYKIQSALLVPTLFSFFAKSTLIDKYDLSNLHEIASGGAPLSKEV 323 Query: 363 QDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDT 542 +A + + QGYG+TE + + +P G+ G VV K+VD DT Sbjct: 324 GEAVAKRFHLPGIRQGYGLTETTSAILITPEGDDKP-----GAVGKVVPFFEAKVVDLDT 378 Query: 543 GASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 G +LG NQ GE+C+RG IM GY+N+PE+T IDKDGWLH+ Sbjct: 379 GKTLGVNQRGELCVRGPMIMSGYVNNPEATNALIDKDGWLHS 420
>LUCI_LUCCR (P13129) Luciferin 4-monooxygenase (EC 1.13.12.7) (Luciferase)| Length = 548 Score = 119 bits (298), Expect = 8e-27 Identities = 72/222 (32%), Positives = 118/222 (53%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV LTH + +T + D N +L ++P H + + + L L G +V Sbjct: 208 KGVQLTHENTVTRFSHARDPIYGN-QVSPGTAVLTVVPFHHGFGMFTTL-GYLICGFRVV 265 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKEL 362 ++ KFD ++ ++ + T VP + + KS + DL+++ + SG AP+ KE+ Sbjct: 266 MLTKFDEETFLKTLQDYKCTSVILVPTLFAILNKSELLNKYDLSNLVEIASGGAPLSKEV 325 Query: 363 QDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDT 542 +A + + QGYG+TE + + +P G+ G VV K++D DT Sbjct: 326 GEAVARRFNLPGVRQGYGLTETTSAIIITPEGDDKP-----GASGKVVPLFKAKVIDLDT 380 Query: 543 GASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 SLG N+ GE+C++G +MKGY+N+PE+TK ID++GWLHT Sbjct: 381 KKSLGPNRRGEVCVKGPMLMKGYVNNPEATKELIDEEGWLHT 422
>LCFA_BACSU (P94547) Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase) Length = 560 Score = 116 bits (291), Expect = 5e-26 Identities = 72/224 (32%), Positives = 119/224 (53%), Gaps = 2/224 (0%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKE--DVLLCLLPLFHIYSLNSVLLAGLRAGSA 176 KGVMLTH++++ + +Y KE + +L ++P FH+Y L +V+ ++ G Sbjct: 222 KGVMLTHQNILANTEMCAAW----MYDVKEGAEKVLGIVPFFHVYGLTAVMNYSIKLGFE 277 Query: 177 MVIMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGK 356 M+++ KFD ++++ H T+ P P I + + P++ DL+SI+ +SG+A + Sbjct: 278 MILLPKFDPLETLKIIDKHKPTLFPGAPTIYIGLLHHPELQHYDLSSIKSCLSGSAALPV 337 Query: 357 ELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDP 536 E++ F K+ L +GYG++EA PV + K K GS G + I Sbjct: 338 EVKQKF-EKVTGGKLVEGYGLSEASPVTHANFIWGKN----KPGSIGCPWPSTDAAIYSE 392 Query: 537 DTGASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 +TG + GEI ++G Q+MKGY N PE T + +DGWL T Sbjct: 393 ETGELAAPYEHGEIIVKGPQVMKGYWNKPEETAAVL-RDGWLFT 435
>LUCI_LUCMI (Q26304) Luciferin 4-monooxygenase (EC 1.13.12.7) (Luciferase)| Length = 548 Score = 114 bits (285), Expect = 3e-25 Identities = 69/222 (31%), Positives = 114/222 (51%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV +TH +T + D N +L ++P H + + + L G +V Sbjct: 208 KGVRITHEGAVTRFSHAKDPIYGN-QVSPGTAILTVVPFHHGFGMFTTL-GYFACGYRVV 265 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKEL 362 ++ KFD + ++ + T VP + + KS + DL+++ + SG AP+ KE+ Sbjct: 266 MLTKFDEELFLRTLQDYKCTSVILVPTLFAILNKSELIDKFDLSNLTEIASGGAPLAKEV 325 Query: 363 QDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDT 542 +A + + QGYG+TE + +P G+ G VV +K++D DT Sbjct: 326 GEAVARRFNLPGVRQGYGLTETTSAFIITPEGDDKP-----GASGKVVPLFKVKVIDLDT 380 Query: 543 GASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 +LG N+ GEIC++G +M GY N+PE+T+ TID++GWLHT Sbjct: 381 KKTLGVNRRGEICVKGPSLMLGYSNNPEATRETIDEEGWLHT 422
>LUCI_LUCLA (Q01158) Luciferin 4-monooxygenase (EC 1.13.12.7) (Luciferase)| Length = 548 Score = 113 bits (283), Expect = 5e-25 Identities = 67/222 (30%), Positives = 118/222 (53%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV LTH + +T + D N +L ++P H + + + L L G +V Sbjct: 208 KGVQLTHENAVTRFSHARDPIYGN-QVSPGTAILTVVPFHHGFGMFTTL-GYLTCGFRIV 265 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKEL 362 ++ KFD ++ ++ + + VP + + +S + DL+++ + SG AP+ KE+ Sbjct: 266 MLTKFDEETFLKTLQDYKCSSVILVPTLFAILNRSELLDKYDLSNLVEIASGGAPLSKEI 325 Query: 363 QDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDT 542 +A + + QGYG+TE + + +P G+ G VV K++D DT Sbjct: 326 GEAVARRFNLPGVRQGYGLTETTSAIIITPEGDDKP-----GASGKVVPLFKAKVIDLDT 380 Query: 543 GASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 +LG N+ GE+C++G +MKGY+++PE+T+ ID++GWLHT Sbjct: 381 KKTLGPNRRGEVCVKGPMLMKGYVDNPEATREIIDEEGWLHT 422
>LUCI_PHOPE (Q27757) Luciferin 4-monooxygenase (EC 1.13.12.7) (Luciferase)| Length = 545 Score = 112 bits (279), Expect = 1e-24 Identities = 66/222 (29%), Positives = 112/222 (50%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGVMLTH++++ + D N +L ++P H + + + L G + Sbjct: 205 KGVMLTHKNIVARFSHCKDPTFGNA-INPTTAILTVIPFHHGFGMTTTL-GYFTCGFRVA 262 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKEL 362 +M F+ ++ ++ + + VP ++ KS V DL+ ++ + SG AP+ KE+ Sbjct: 263 LMHTFEEKLFLQSLQDYKVESTLLVPTLMAFFPKSALVEKYDLSHLKEIASGGAPLSKEI 322 Query: 363 QDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDT 542 + + + QGYG+TE + + V+ GS G +V +K+VDP T Sbjct: 323 GEMVKKRFKLNFVRQGYGLTETTSAVLIT-----PDTDVRPGSTGKIVPFHAVKVVDPTT 377 Query: 543 GASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 G LG N+ GE+ +G+ IMK Y N+ E+TK I+KDGWL + Sbjct: 378 GKILGPNETGELYFKGDMIMKSYYNNEEATKAIINKDGWLRS 419
>LCFA_ECO57 (Q8XDR6) Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase) (Acyl-CoA synthetase) Length = 561 Score = 103 bits (256), Expect = 6e-22 Identities = 71/226 (31%), Positives = 120/226 (53%), Gaps = 4/226 (1%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSL--NSVLLAGLRAGSA 176 KG MLTHR+++ ++ Q P L+ KE +++ LPL+HI++L N +L L G Sbjct: 222 KGAMLTHRNMLANLEQVNATYGPLLHPGKE-LVVTALPLYHIFALTINCLLFIEL-GGQN 279 Query: 177 MVIMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGK 356 ++I DI LV+ + + T V + + + + D +S+ + G P+ + Sbjct: 280 LLITNPRDIPGLVKELAKYPFTAITGVNTLFNALLNNKEFQQLDFSSLHLSAGGGMPVQQ 339 Query: 357 ELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVK--SGSCGTVVRNAGLKIV 530 + + ++ K+ L +GYG+TE P++++ P+ + SGS G V + K+V Sbjct: 340 VVAERWV-KLTGQYLLEGYGLTECAPLVSV------NPYDIDYHSGSIGLPVPSTEAKLV 392 Query: 531 DPDTGASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 D D + QPGE+C+RG Q+M GY P++T I K+GWLHT Sbjct: 393 DDDDN-EVSPGQPGELCVRGPQVMLGYWQRPDATDEII-KNGWLHT 436
>LCFA_ECOLI (P69451) Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase) (Acyl-CoA synthetase) Length = 561 Score = 101 bits (251), Expect = 2e-21 Identities = 70/226 (30%), Positives = 120/226 (53%), Gaps = 4/226 (1%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSL--NSVLLAGLRAGSA 176 KG MLTHR+++ ++ Q P L+ KE +++ LPL+HI++L N +L L G Sbjct: 222 KGAMLTHRNMLANLEQVNATYGPLLHPGKE-LVVTALPLYHIFALTINCLLFIEL-GGQN 279 Query: 177 MVIMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGK 356 ++I DI LV+ + + T V + + + + D +S+ + G P+ + Sbjct: 280 LLITNPRDIPGLVKELAKYPFTAITGVNTLFNALLNNKEFQQLDFSSLHLSAGGGMPVQQ 339 Query: 357 ELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVK--SGSCGTVVRNAGLKIV 530 + + ++ K+ L +GYG+TE P++++ P+ + SGS G V + K+V Sbjct: 340 VVAERWV-KLTGQYLLEGYGLTECAPLVSV------NPYDIDYHSGSIGLPVPSTEAKLV 392 Query: 531 DPDTGASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 D D + QPGE+C++G Q+M GY P++T I K+GWLHT Sbjct: 393 DDDDN-EVPPGQPGELCVKGPQVMLGYWQRPDATDEII-KNGWLHT 436
>LCFA_ECOL6 (P69452) Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase) (Acyl-CoA synthetase) Length = 561 Score = 101 bits (251), Expect = 2e-21 Identities = 70/226 (30%), Positives = 120/226 (53%), Gaps = 4/226 (1%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSL--NSVLLAGLRAGSA 176 KG MLTHR+++ ++ Q P L+ KE +++ LPL+HI++L N +L L G Sbjct: 222 KGAMLTHRNMLANLEQVNATYGPLLHPGKE-LVVTALPLYHIFALTINCLLFIEL-GGQN 279 Query: 177 MVIMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGK 356 ++I DI LV+ + + T V + + + + D +S+ + G P+ + Sbjct: 280 LLITNPRDIPGLVKELAKYPFTAITGVNTLFNALLNNKEFQQLDFSSLHLSAGGGMPVQQ 339 Query: 357 ELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVK--SGSCGTVVRNAGLKIV 530 + + ++ K+ L +GYG+TE P++++ P+ + SGS G V + K+V Sbjct: 340 VVAERWV-KLTGQYLLEGYGLTECAPLVSV------NPYDIDYHSGSIGLPVPSTEAKLV 392 Query: 531 DPDTGASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 D D + QPGE+C++G Q+M GY P++T I K+GWLHT Sbjct: 393 DDDDN-EVPPGQPGELCVKGPQVMLGYWQRPDATDEII-KNGWLHT 436
>LCFA_SALTY (P63521) Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase) Length = 561 Score = 98.6 bits (244), Expect = 2e-20 Identities = 68/224 (30%), Positives = 115/224 (51%), Gaps = 2/224 (0%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSL--NSVLLAGLRAGSA 176 KG MLTHR+++ ++ Q P L+ KE +++ LPL+HI++L N +L L G Sbjct: 222 KGAMLTHRNMLANLEQVKATYGPLLHPGKE-LVVTALPLYHIFALTMNCLLFIEL-GGQN 279 Query: 177 MVIMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGK 356 ++I DI LV+ + + T V + + + + D +S+ + G P+ Sbjct: 280 LLITNPRDIPGLVKELAKYPFTAMTGVNTLFNALLNNKEFQQLDFSSLHLSAGGGMPVQN 339 Query: 357 ELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDP 536 + + ++ K+ L +GYG+TE P++++ SGS G V + K+VD Sbjct: 340 VVAERWV-KLTGQYLLEGYGLTECAPLVSV----NPHDIDYHSGSIGLPVPSTEAKLVDD 394 Query: 537 DTGASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 D + + GE+C++G Q+M GY P++T I KDGWLHT Sbjct: 395 DDN-EVAPGEAGELCVKGPQVMLGYWQRPDATDEII-KDGWLHT 436
>LCFA_SALTI (P63522) Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase) Length = 561 Score = 98.6 bits (244), Expect = 2e-20 Identities = 68/224 (30%), Positives = 115/224 (51%), Gaps = 2/224 (0%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSL--NSVLLAGLRAGSA 176 KG MLTHR+++ ++ Q P L+ KE +++ LPL+HI++L N +L L G Sbjct: 222 KGAMLTHRNMLANLEQVKATYGPLLHPGKE-LVVTALPLYHIFALTMNCLLFIEL-GGQN 279 Query: 177 MVIMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGK 356 ++I DI LV+ + + T V + + + + D +S+ + G P+ Sbjct: 280 LLITNPRDIPGLVKELAKYPFTAMTGVNTLFNALLNNKEFQQLDFSSLHLSAGGGMPVQN 339 Query: 357 ELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDP 536 + + ++ K+ L +GYG+TE P++++ SGS G V + K+VD Sbjct: 340 VVAERWV-KLTGQYLLEGYGLTECAPLVSV----NPHDIDYHSGSIGLPVPSTEAKLVDD 394 Query: 537 DTGASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 D + + GE+C++G Q+M GY P++T I KDGWLHT Sbjct: 395 DDN-EVAPGEAGELCVKGPQVMLGYWQRPDATDEII-KDGWLHT 436
>LCFA_YERPE (Q8ZES9) Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase) Length = 562 Score = 91.7 bits (226), Expect = 2e-18 Identities = 66/226 (29%), Positives = 120/226 (53%), Gaps = 4/226 (1%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSL--NSVLLAGLRAGSA 176 KG +LTHR++ +++ Q P L + D+++ LPL+HI++L N +L L G + Sbjct: 222 KGAILTHRNMQSNLEQAKAAYAPLLQPGR-DLVVTALPLYHIFALTVNCLLFIEL-GGRS 279 Query: 177 MVIMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGK 356 ++I DI +V+ + + T V + + + + T D +++R+ + G P+ K Sbjct: 280 LLITNPRDIPGMVKELSRYPFTAITGVNTLFNALLNNEEFTHLDFSTLRLSVGGGMPVQK 339 Query: 357 ELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVK--SGSCGTVVRNAGLKIV 530 + + + +L +GYG+TE P++ P+ +K SGS G V + +++ Sbjct: 340 AVAEKWETLTGKHLL-EGYGLTECSPLVT------GNPYDLKHYSGSIGLPVPSTDVRLR 392 Query: 531 DPDTGASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 D D G + +PGE+ +RG Q+M GY P++T + + KDGWL T Sbjct: 393 DDD-GNDVELGKPGELWVRGPQVMLGYWQRPDATDDVL-KDGWLAT 436
>LCFA_HAEIN (P46450) Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase) Length = 562 Score = 87.4 bits (215), Expect = 3e-17 Identities = 63/227 (27%), Positives = 114/227 (50%), Gaps = 5/227 (2%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNL--YFRKEDVLLCLLPLFHIYSLNSVLLAGLRAG-S 173 KG MLTH ++IT+V Q P + + R +L L PL+H+++L L L G + Sbjct: 222 KGAMLTHGNIITNVFQAKWIAEPFIGDHSRTRSAILAL-PLYHVFALTVNCLLFLELGVT 280 Query: 174 AMVIMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMG 353 A++I DI V+ ++ + V + + + D +++++ + G + Sbjct: 281 AILITNPRDIEGFVKELKKYRFEAITGVNTLFNALLNNENFKEVDFSALKLSVGGGMAIQ 340 Query: 354 KELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKV--KSGSCGTVVRNAGLKI 527 + + + ++ + +GYGMTE P++A C P V +G+ G V N +KI Sbjct: 341 QSVATRWH-ELTGCNIIEGYGMTECSPLIAAC------PINVVKHNGTIGVPVPNTDIKI 393 Query: 528 VDPDTGASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 + D G+ + GE+ ++G+Q+M+GY PE+T + KDGW+ T Sbjct: 394 IKDD-GSDAKIGEAGELWVKGDQVMRGYWQRPEATSEVL-KDGWMAT 438
>ACSL5_RAT (O88813) Long-chain-fatty-acid--CoA ligase 5 (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase 5) (LACS 5) Length = 683 Score = 81.6 bits (200), Expect = 2e-15 Identities = 73/263 (27%), Positives = 115/263 (43%), Gaps = 41/263 (15%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KG MLTH+++++++A + P EDV + LPL H++ ++ + + + Sbjct: 269 KGAMLTHQNIVSNMAAFLKFLEPIFQPTPEDVTISYLPLAHMF--ERLVQGVIFSCGGKI 326 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEI-------AKSP---------------QV 296 + DI L + ++A TV P VP ++ + AK+P +V Sbjct: 327 GFFQGDIRLLPDDMKALKPTVFPTVPRLLNRVYDKVQNEAKTPLKKFLLNLAIISKFNEV 386 Query: 297 TAGDL-------------------ASIRMVMSGAAPMGKELQDAFMAKIPNAVLGQGYGM 419 G + +R++++GAAP+ + F A + V + YG Sbjct: 387 RNGIIRRNSLWDKLVFSKIQSSLGGKVRLMITGAAPISTPVLTFFRAAMGCWVF-EAYGQ 445 Query: 420 TEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGASLGRNQPGEICIRGEQI 599 TE A C P +G GT V +K+ D N GEICI+G + Sbjct: 446 TEC---TAGC--SITSPGDWTAGHVGTPVSCNFVKLEDVADMNYFSVNNEGEICIKGNNV 500 Query: 600 MKGYLNDPESTKNTIDKDGWLHT 668 KGYL DPE T+ +DKDGWLHT Sbjct: 501 FKGYLKDPEKTQEVLDKDGWLHT 523
>ACSL5_MOUSE (Q8JZR0) Long-chain-fatty-acid--CoA ligase 5 (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase 5) (LACS 5) Length = 683 Score = 80.1 bits (196), Expect = 6e-15 Identities = 73/264 (27%), Positives = 115/264 (43%), Gaps = 42/264 (15%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAG-LRAGSAM 179 KG MLTH ++++++A + P +DV + LPL H++ L+ G L + Sbjct: 269 KGAMLTHENVVSNMAAFLKFLEPIFQPTSDDVTISYLPLAHMFER---LVQGILFSCGGK 325 Query: 180 VIMRKFDIGALVELVRAHGITVAPFVPPIVVEI-------AKSP---------------Q 293 + + DI L + ++A TV P VP ++ + AK+P + Sbjct: 326 IGFFQGDIRLLPDDMKALKPTVFPTVPRLLNRVYDKVQNEAKTPLKKFLLNLAIISKFNE 385 Query: 294 VTAGDL-------------------ASIRMVMSGAAPMGKELQDAFMAKIPNAVLGQGYG 416 V G + +R++++GAAP+ + F A + V + YG Sbjct: 386 VKNGIIRRDSLWDKLVFSKIQGSLGGKVRLMITGAAPISTPVLTFFRAAMGCWVF-EAYG 444 Query: 417 MTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGASLGRNQPGEICIRGEQ 596 TE ++ P +G GT V +K+ D N GEICI+G Sbjct: 445 QTECTGGCSIT-----SPGDWTAGHVGTPVACNFVKLEDVADMNYFSVNNEGEICIKGNN 499 Query: 597 IMKGYLNDPESTKNTIDKDGWLHT 668 + KGYL DPE T+ +DKDGWLHT Sbjct: 500 VFKGYLKDPEKTQEVLDKDGWLHT 523
>ACSL1_MOUSE (P41216) Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase 1) (LACS 1) Length = 699 Score = 79.3 bits (194), Expect = 9e-15 Identities = 64/263 (24%), Positives = 110/263 (41%), Gaps = 41/263 (15%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KG M+TH+++I + + +DVL+ LPL H++ +V+ + A + Sbjct: 285 KGAMITHQNIINDCSGFIKATESAFIASTDDVLISFLPLAHMFE--TVVECVMLCHGAKI 342 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEI----------------------AKSPQV 296 + DI L++ ++ T+ P VP ++ + K V Sbjct: 343 GFFQGDIRLLMDDLKVLQPTIFPVVPRLLNRMFDRIFGQANTSLKRWLLDFASKRKEADV 402 Query: 297 TAGDLAS-------------------IRMVMSGAAPMGKELQDAFMAKIPNAVLGQGYGM 419 +G + + +R++++GAAP+ + F+ +GYG Sbjct: 403 RSGIVRNNSLWDKLIFHKIQSSLGGKVRLMITGAAPVSATVL-TFLRTALGCQFYEGYGQ 461 Query: 420 TEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGASLGRNQPGEICIRGEQI 599 TE CL+ P +G G + +K+VD + L GE+C++G + Sbjct: 462 TEC--TAGCCLSL---PGDWTAGHVGAPMPCNYVKLVDVEEMNYLASKGEGEVCVKGANV 516 Query: 600 MKGYLNDPESTKNTIDKDGWLHT 668 KGYL DP T +DKDGWLHT Sbjct: 517 FKGYLKDPARTAEALDKDGWLHT 539
>ACSL1_CAVPO (Q9JID6) Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase 1) (LACS 1) (Palmitoyl-CoA ligase) Length = 698 Score = 79.3 bits (194), Expect = 9e-15 Identities = 61/263 (23%), Positives = 111/263 (42%), Gaps = 41/263 (15%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KG M+TH+++++ + V L D+ + LPL H+Y +L + A + Sbjct: 284 KGAMITHKNVVSDCSAFVKATEKALVLNASDIHISFLPLAHMYE--QLLQCVMLCHGAKI 341 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEI----------------------AKSPQV 296 + DI L++ ++A T+ P VP ++ + K ++ Sbjct: 342 GFFQGDIRLLMDDLKALQPTIFPVVPRLLNRMFDRIFAQANTTVKRWLLDFASKRKEAEL 401 Query: 297 TAGDLAS-------------------IRMVMSGAAPMGKELQDAFMAKIPNAVLGQGYGM 419 +G + + +R++++GAAP+ + F+ +GYG Sbjct: 402 RSGIIRNNSVWDKLIFHKIQSSLGGKVRLMVTGAAPVSATVL-TFLRAALGCQFYEGYGQ 460 Query: 420 TEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGASLGRNQPGEICIRGEQI 599 TE ++ + P +G G + +K+VD + + GE+C++G + Sbjct: 461 TECTAGCSLSV-----PGDWTAGHVGAPMPCNFIKLVDVEEMNYMAAMGEGEVCVKGPNV 515 Query: 600 MKGYLNDPESTKNTIDKDGWLHT 668 KGYL DP T +DKDGWLHT Sbjct: 516 FKGYLKDPAKTAEALDKDGWLHT 538
>MENE_BACCR (Q816I1) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 482 Score = 78.6 bits (192), Expect = 2e-14 Identities = 63/223 (28%), Positives = 110/223 (49%), Gaps = 1/223 (0%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV+LT+ + S G + NL R +D L +P+FH+ L S+L+ + G ++ Sbjct: 156 KGVILTYGNHWASAV----GSSLNLGLRDDDCWLACMPMFHVGGL-SLLMKNIMYGMRIL 210 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKEL 362 ++ K+D + + ++ G+T+ V ++ ++ + +S+R ++ G P K L Sbjct: 211 LVPKYDADFIHKALQTRGVTIISVVSKMLTDLLERLGAETYP-SSLRCMLLGGGPAPKPL 269 Query: 363 QDAFMAK-IPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPD 539 +A + K IP + Q YGMTE + A + K GS G + L+I Sbjct: 270 LEACVEKGIP---VYQTYGMTETSSQICTLSA---DYMLTKVGSAGKPLFQCQLRI--EK 321 Query: 540 TGASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 G + GEI ++G + GY N ++T+ TI ++GWLHT Sbjct: 322 DGVVVPPLVEGEIVVKGPNVTGGYFNREDATRETI-QNGWLHT 363
>MENE_BACC1 (Q72YK9) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 481 Score = 77.8 bits (190), Expect = 3e-14 Identities = 62/223 (27%), Positives = 109/223 (48%), Gaps = 1/223 (0%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV+LT+ + S G + NL R +D L +P+FH+ L S+L+ + G ++ Sbjct: 155 KGVILTYGNHWASAV----GSSLNLGLRDDDCWLACMPMFHVGGL-SLLMKNIMYGMRIL 209 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKEL 362 ++ K+D + + ++ G+T+ V ++ ++ + +S+R ++ G P K L Sbjct: 210 LVPKYDADFIHKALQTRGVTIISVVSKMLTDLLERLGAETYP-SSLRCMLLGGGPAPKPL 268 Query: 363 QDAFMAK-IPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPD 539 + + K IP + Q YGMTE + A + K GS G + L+I Sbjct: 269 LETCVEKGIP---VYQTYGMTETSSQICTLSA---DYMLTKVGSAGKPLFQCQLRI--EK 320 Query: 540 TGASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 G + GEI ++G + GY N ++T+ TI ++GWLHT Sbjct: 321 DGVVVPAFTEGEIVVKGPNVTGGYFNREDATRETI-QNGWLHT 362
>MENE_BACHK (Q6HC29) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 482 Score = 77.4 bits (189), Expect = 4e-14 Identities = 63/224 (28%), Positives = 112/224 (50%), Gaps = 2/224 (0%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV+LT+ + S G + NL R +D L +P+FH+ L S+L+ + G ++ Sbjct: 156 KGVILTYGNHWASAV----GSSLNLGLRDDDCWLACMPMFHVGGL-SLLMKNIMYGMRIL 210 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDL-ASIRMVMSGAAPMGKE 359 ++ K+D + + ++ G+T+ V ++ ++ + ++ G +S+R ++ G P K Sbjct: 211 LVPKYDADFIHKALQTRGVTIISVVSKMLTDLLE--RLGEGTYPSSLRCMLLGGGPAPKP 268 Query: 360 LQDAFMAK-IPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDP 536 L + + K IP + Q YGMTE + A + K GS G + L+I Sbjct: 269 LLETCVDKGIP---VYQTYGMTETSSQICTLSA---DYMLTKVGSAGKPLFQCQLRI--E 320 Query: 537 DTGASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 G + GEI ++G + GY N ++T+ TI ++GWLHT Sbjct: 321 KDGVVVPPFAEGEIVVKGPNVTGGYFNREDATRETI-QNGWLHT 363
>MENE_BACCZ (Q632I5) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 482 Score = 77.4 bits (189), Expect = 4e-14 Identities = 63/223 (28%), Positives = 110/223 (49%), Gaps = 1/223 (0%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV+LT+ + S G + NL R +D L +P+FH+ L S+L+ + G ++ Sbjct: 156 KGVILTYGNHWASAV----GSSFNLGLRDDDCWLACMPMFHVGGL-SLLMKNIMYGMRIL 210 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKEL 362 ++ K+D + + ++ G+T+ V ++ ++ + S+R ++ G P K L Sbjct: 211 LVPKYDADFIHKALQTRGVTIISVVSKMLTDLLERLGEETYP-PSLRCMLLGGGPAPKPL 269 Query: 363 QDAFMAK-IPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPD 539 +A + K IP + Q YGMTE + A + +K GS G + L+I Sbjct: 270 LEACVEKRIP---VYQTYGMTETSSQICTLSA---DYMLMKVGSAGKPLFQCQLRI--EK 321 Query: 540 TGASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 G + GEI ++G + GY N ++T+ TI ++GWLHT Sbjct: 322 DGVVVPPFAEGEIVVKGPNVTGGYFNREDATRETI-QNGWLHT 363
>ACSL6_MOUSE (Q91WC3) Long-chain-fatty-acid--CoA ligase 6 (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase 6) (LACS 6) Length = 697 Score = 77.0 bits (188), Expect = 5e-14 Identities = 70/263 (26%), Positives = 113/263 (42%), Gaps = 41/263 (15%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KG MLTH +++ + + ++ R++DVL+ LPL H++ V+ + + V Sbjct: 284 KGAMLTHGNVVADFSGFLKVTEKVIFPRQDDVLISFLPLAHMFE--RVIQSVVYCHGGRV 341 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIV-------------------VEIA---KSPQV 296 + DI L + ++A T+ P VP ++ +E A K +V Sbjct: 342 GFFQGDIRLLSDDMKALRPTIFPVVPRLLNRMYDKIFHQADTSLKRWLLEFAAKRKQAEV 401 Query: 297 TAGDLAS-------------------IRMVMSGAAPMGKELQDAFMAKIPNAVLGQGYGM 419 +G + + +RM+++GAAP + A + V +GYG Sbjct: 402 RSGIIRNNSIWDELFFNKIQASLGGHVRMIVTGAAPASPTVLGFLRAALGCQVY-EGYGQ 460 Query: 420 TEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGASLGRNQPGEICIRGEQI 599 TE A C P SG G + +K+VD + GEIC++G + Sbjct: 461 TEC---TAGCTFTT--PGDWTSGHVGAPLPCNHIKLVDAEELNYWTCKGEGEICVKGPNV 515 Query: 600 MKGYLNDPESTKNTIDKDGWLHT 668 KGYL D + TK +D DGWLHT Sbjct: 516 FKGYLKDEDRTKEALDSDGWLHT 538
>MENE_BACAN (Q81K97) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 481 Score = 76.6 bits (187), Expect = 6e-14 Identities = 63/224 (28%), Positives = 111/224 (49%), Gaps = 2/224 (0%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV+LT+ + S G + NL R +D L +P+FH+ L S+L+ + G ++ Sbjct: 155 KGVILTYGNHWASAV----GSSLNLGLRDDDCWLACMPMFHVGGL-SLLMKNIMYGMRIL 209 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDL-ASIRMVMSGAAPMGKE 359 ++ K+D + + ++ G+T+ V ++ ++ + ++ G +S R ++ G P K Sbjct: 210 LVPKYDADFIHKALQTRGVTIISVVSKMLTDLLE--RLGEGTYPSSFRCMLLGGGPAPKP 267 Query: 360 LQDAFMAK-IPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDP 536 L + + K IP + Q YGMTE + A + K GS G + L+I Sbjct: 268 LLETCVDKGIP---VYQTYGMTETSSQICTLSA---DYMLTKVGSAGKPLFQCQLRI--E 319 Query: 537 DTGASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 G + GEI ++G + GY N ++T+ TI ++GWLHT Sbjct: 320 KDGVVVPPFAEGEIVVKGPNVTGGYFNREDATRETI-QNGWLHT 362
>ACSL1_RAT (P18163) Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase 1) (LACS 1) (Long-chain-fatty-acid--CoA ligase, liver isozyme) Length = 699 Score = 76.6 bits (187), Expect = 6e-14 Identities = 62/263 (23%), Positives = 110/263 (41%), Gaps = 41/263 (15%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KG M+TH++++ + + EDVL+ LPL H++ +V+ + A + Sbjct: 285 KGAMVTHQNIMNDCSGFIKATESAFIASPEDVLISFLPLAHMFE--TVVECVMLCHGAKI 342 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEI----------------------AKSPQV 296 + DI L++ ++ T+ P VP ++ + K ++ Sbjct: 343 GFFQGDIRLLMDDLKVLQPTIFPVVPRLLNRMFDRIFGQANTSVKRWLLDFASKRKEAEL 402 Query: 297 TAGDLAS-------------------IRMVMSGAAPMGKELQDAFMAKIPNAVLGQGYGM 419 +G + + +R++++GAAP+ + F+ +GYG Sbjct: 403 RSGIVRNNSLWDKLIFHKIQSSLGGKVRLMITGAAPVSATVL-TFLRAALGCQFYEGYGQ 461 Query: 420 TEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGASLGRNQPGEICIRGEQI 599 TE CL+ P +G G + +K+VD + GE+C++G + Sbjct: 462 TEC--TAGCCLSL---PGDWTAGHVGAPMPCNYIKLVDVEDMNYQAAKGEGEVCVKGANV 516 Query: 600 MKGYLNDPESTKNTIDKDGWLHT 668 KGYL DP T +DKDGWLHT Sbjct: 517 FKGYLKDPARTAEALDKDGWLHT 539
>ACSL5_HUMAN (Q9ULC5) Long-chain-fatty-acid--CoA ligase 5 (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase 5) (LACS 5) Length = 683 Score = 75.9 bits (185), Expect = 1e-13 Identities = 68/263 (25%), Positives = 111/263 (42%), Gaps = 41/263 (15%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KG M+TH++++++ A + +DV + LPL H++ ++ A + + A V Sbjct: 269 KGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPLAHMFE--RIVQAVVYSCGARV 326 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEI-------AKSP---------------QV 296 + DI L + ++ T+ P VP ++ I AK+P ++ Sbjct: 327 GFFQGDIRLLADDMKTLKPTLFPAVPRLLNRIYDKVQNEAKTPLKKFLLKLAVSSKFKEL 386 Query: 297 TAGDL-------------------ASIRMVMSGAAPMGKELQDAFMAKIPNAVLGQGYGM 419 G + +R++++GAAPM + F A + V + YG Sbjct: 387 QKGIIRHDSFWDKLIFAKIQDSLGGRVRVIVTGAAPMSTSVMTFFRAAMGCQVY-EAYGQ 445 Query: 420 TEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGASLGRNQPGEICIRGEQI 599 TE L P SG G + +K+ D N GE+CI+G + Sbjct: 446 TECTGGCTFTL-----PGDWTSGHVGVPLACNYVKLEDVADMNYFTVNNEGEVCIKGTNV 500 Query: 600 MKGYLNDPESTKNTIDKDGWLHT 668 KGYL DPE T+ +D DGWLHT Sbjct: 501 FKGYLKDPEKTQEALDSDGWLHT 523
>ACSL1_HUMAN (P33121) Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase 1) (LACS 1) (Palmitoyl-CoA ligase 1) (Long-chain fatty acid CoA ligase 2) (Long-chain acyl-CoA synthetase 2) (LACS 2) (Acyl-CoA synthetase 1) (ACS1) (Pa Length = 698 Score = 75.9 bits (185), Expect = 1e-13 Identities = 62/263 (23%), Positives = 110/263 (41%), Gaps = 41/263 (15%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KG M+THR++++ + V + +D L+ LPL H++ V+ + A + Sbjct: 284 KGAMVTHRNIVSDCSAFVKATENTVNPCPDDTLISFLPLAHMFE--RVVECVMLCHGAKI 341 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEI----------------------AKSPQV 296 + DI L++ ++ TV P VP ++ + K ++ Sbjct: 342 GFFQGDIRLLMDDLKVLQPTVFPVVPRLLNRMFDRIFGQANTTLKRWLLDFASKRKEAEL 401 Query: 297 TAGDLAS-------------------IRMVMSGAAPMGKELQDAFMAKIPNAVLGQGYGM 419 +G + + +R++++GAAP+ + F+ +GYG Sbjct: 402 RSGIIRNNSLWDRLIFHKVQSSLGGRVRLMVTGAAPVSATVL-TFLRAALGCQFYEGYGQ 460 Query: 420 TEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGASLGRNQPGEICIRGEQI 599 TE CL P +G G + +K+VD + + GE+C++G + Sbjct: 461 TEC--TAGCCLTM---PGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEGEGEVCVKGPNV 515 Query: 600 MKGYLNDPESTKNTIDKDGWLHT 668 +GYL DP T +DKDGWLHT Sbjct: 516 FQGYLKDPAKTAEALDKDGWLHT 538
>MENE_ENTFA (Q838K1) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 485 Score = 75.1 bits (183), Expect = 2e-13 Identities = 67/223 (30%), Positives = 106/223 (47%), Gaps = 1/223 (0%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV+ ++ + S G N+ ED LC +PLFHI L S+++ L G ++ Sbjct: 155 KGVLQRFKNHLASAR----GTQENMGITAEDCWLCAVPLFHISGL-SIVVRQLVLGCSIR 209 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKE- 359 + KFD + + ++ TV V ++ ++ S AG AS + ++ G P+ + Sbjct: 210 LYDKFDEQQVTQDLQEGRGTVISVVATMLQQLL-SVYPEAGYSASFKGMLLGGGPIAPDK 268 Query: 360 LQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPD 539 L IP + Q YGMTE + +A E +K GS G +++ +KIVD + Sbjct: 269 LAQCEEKGIP---VIQSYGMTET---CSQVVALKFEDAALKIGSAGQPLKDMQIKIVD-E 321 Query: 540 TGASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 G Q GEI ++G ++ GYLN + K T DGW T Sbjct: 322 LGQEQPEKQVGEILLKGPNVVSGYLNQRQPEKWT--ADGWFKT 362
>FAT2_SCHPO (O74976) Putative peroxisomal-coenzyme A synthetase (EC 6.-.-.-)| Length = 512 Score = 75.1 bits (183), Expect = 2e-13 Identities = 66/224 (29%), Positives = 102/224 (45%), Gaps = 2/224 (0%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKE--DVLLCLLPLFHIYSLNSVLLAGLRAGSA 176 K V LTH++L S+ N +R + D ++PLFH++ L LL+ L +G Sbjct: 177 KVVPLTHKNLCRSI------HNITTSYRLDPRDTSYVVMPLFHVHGLLCGLLSTLASGGC 230 Query: 177 MVIMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGK 356 V+ KF + + +G T VP I + ++P L IR + S ++P+ Sbjct: 231 AVVPPKFSAHSFWKEFIQYGATWYTAVPTIHQILLRTPPPKP--LPRIRFIRSCSSPLAP 288 Query: 357 ELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDP 536 + A VL + Y MTEA + P K S G LKI+D Sbjct: 289 PVLSKLEATFRAPVL-EAYAMTEASHQMT---TNPLPPLVHKPHSVGKPF-GVELKILD- 342 Query: 537 DTGASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 G + + + GEIC+RG + KGYLN+P + K++ KD + T Sbjct: 343 QKGNEMPQGKEGEICVRGINVTKGYLNNPAANKSSFTKDRFFRT 386
>LCF2_YEAST (P39518) Long-chain-fatty-acid--CoA ligase 2 (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase 2) (Fatty acid activator 2) Length = 744 Score = 72.0 bits (175), Expect = 2e-12 Identities = 69/278 (24%), Positives = 113/278 (40%), Gaps = 56/278 (20%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQV-------DGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGL 161 KGV ++HR++ + +A D N LY +C LPL HI+ V+ L Sbjct: 308 KGVEMSHRNIASGIAFAFSTFRIPPDKRNQQLYD------MCFLPLAHIFE-RMVIAYDL 360 Query: 162 RAGSAMVIMRKFDIGALVELVRAHGITVAPFVPPIVVEI--------------------- 278 G + + K D LVE ++ VP I+ Sbjct: 361 AIGFGIGFLHKPDPTVLVEDLKILKPYAVALVPRILTRFEAGIKNALDKSTVQRNVANTI 420 Query: 279 --AKSPQVTAGD-------------------------LASIRMVMSGAAPMGKELQDAFM 377 +KS + TA L++ +++G+AP+ K+ F+ Sbjct: 421 LDSKSARFTARGGPDKSIMNFLVYHRVLIDKIRDSLGLSNNSFIITGSAPISKDTL-LFL 479 Query: 378 AKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVD-PDTGASL 554 + + QGYG+TE +CL+ EPF+ GSCG + +A ++ P+ G Sbjct: 480 RSALDIGIRQGYGLTET--FAGVCLS---EPFEKDVGSCGAIGISAECRLKSVPEMGYHA 534 Query: 555 GRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 ++ GE+ IRG Q+ + Y +P T +D+DGW T Sbjct: 535 DKDLKGELQIRGPQVFERYFKNPNETSKAVDQDGWFST 572
>CAIC_SALTI (Q8Z9L4) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 517 Score = 71.6 bits (174), Expect = 2e-12 Identities = 63/225 (28%), Positives = 101/225 (44%), Gaps = 3/225 (1%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV++TH +L + + R +DV + ++P FHI + + AGS V Sbjct: 189 KGVVITHYNLRFAGYYSAW----QIALRDDDVYMTVMPAFHIDCQCTAAMPAFSAGSTFV 244 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKEL 362 ++ K+ A + VR + TV +P ++ + P +R VM +E Sbjct: 245 LLEKYSARAFWDQVRKYQATVTECIPMMIRTLMVQPATPTDRQHHLREVMFYLNLSAQE- 303 Query: 363 QDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDT 542 +DAF + +L YGMTE + + + K + S G V + +I D D Sbjct: 304 KDAFTERFGVRLL-TSYGMTET----IVGIIGDRPGDKRRWPSIGRVGFSYEAEIRD-DQ 357 Query: 543 GASLGRNQPGEICIR---GEQIMKGYLNDPESTKNTIDKDGWLHT 668 L + GEICI+ G+ I K Y PE+T ++ +GWLHT Sbjct: 358 NRPLPAGEIGEICIKGIPGKTIFKEYYMQPEATARALEPEGWLHT 402
>CAIC_SALCH (Q57TJ0) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 517 Score = 71.6 bits (174), Expect = 2e-12 Identities = 63/225 (28%), Positives = 101/225 (44%), Gaps = 3/225 (1%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV++TH +L + + R +DV + ++P FHI + + AGS V Sbjct: 189 KGVVITHYNLRFAGYYSAW----QIALRDDDVYMTVMPAFHIDCQCTAAMPAFSAGSTFV 244 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKEL 362 ++ K+ A + VR + TV +P ++ + P +R VM +E Sbjct: 245 LLEKYSARAFWDQVRRYQATVTECIPMMIRTLMVQPAAPTDRQHHLREVMFYLNLSAQE- 303 Query: 363 QDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDT 542 +DAF + +L YGMTE + + + K + S G V + +I D D Sbjct: 304 KDAFTERFGVRLL-TSYGMTET----IVGIIGDRPGDKRRWPSIGRVGFSYEAEIRD-DQ 357 Query: 543 GASLGRNQPGEICIR---GEQIMKGYLNDPESTKNTIDKDGWLHT 668 L + GEICI+ G+ I K Y PE+T ++ +GWLHT Sbjct: 358 NRPLPAGEIGEICIKGIPGKTIFKEYYMQPEATAGALEPEGWLHT 402
>CAIC_SALPA (Q5PIL0) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 517 Score = 70.1 bits (170), Expect = 6e-12 Identities = 63/225 (28%), Positives = 100/225 (44%), Gaps = 3/225 (1%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV++TH +L + + R +DV + ++P FHI + + AGS V Sbjct: 189 KGVVITHYNLRFAGYYSAW----QIALRDDDVYMTVMPAFHIDCQCTAAMPAFSAGSTFV 244 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKEL 362 ++ K+ A VR + TV +P ++ + P +R VM +E Sbjct: 245 LLEKYSARAFWGQVRKYQATVTECIPMMIRTLMVQPAAPTDRQHHLREVMFYLNLSAQE- 303 Query: 363 QDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDT 542 +DAF + +L YGMTE + + + K + S G V + +I D D Sbjct: 304 KDAFTERFGVRLL-TSYGMTET----IVGIIGDRPGDKRRWPSIGRVGFSYEAEIRD-DQ 357 Query: 543 GASLGRNQPGEICIR---GEQIMKGYLNDPESTKNTIDKDGWLHT 668 L + GEICI+ G+ I K Y PE+T ++ +GWLHT Sbjct: 358 NRPLPAGEIGEICIKGIPGKTIFKEYYMQPEATARALEPEGWLHT 402
>MENE_OCEIH (Q8ENZ7) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 480 Score = 69.7 bits (169), Expect = 7e-12 Identities = 58/202 (28%), Positives = 88/202 (43%), Gaps = 3/202 (1%) Frame = +3 Query: 72 NLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMVIMRKFDIGALVELVRAHGITVAP 251 NL D L LPLFH+ L S +L + G + ++ KF++ + + +T+ Sbjct: 180 NLGLHDNDKWLIPLPLFHVSGL-STMLKSVIYGMPIYVLEKFEVEKVHNAIMDRKVTIVS 238 Query: 252 FVPPIVVEIAKSPQVTAGDLA---SIRMVMSGAAPMGKELQDAFMAKIPNAVLGQGYGMT 422 V +V + K G+ R ++ G P K L + AK+ N + Q YGMT Sbjct: 239 VVTVMVQRLIKR----LGNHHYPNDFRCMLLGGGPAPKSLLE--QAKLKNIPVFQSYGMT 292 Query: 423 EAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGASLGRNQPGEICIRGEQIM 602 E + + E K GS G + A LKI + NQ GEI ++G + Sbjct: 293 ETS---SQIVTLTPEDALKKIGSAGKPLFPAQLKIAHNENNP----NQIGEILVKGPMVT 345 Query: 603 KGYLNDPESTKNTIDKDGWLHT 668 KGY E+ K + + WLHT Sbjct: 346 KGYYKRAETNKEVFE-NNWLHT 366
>ACSL6_HUMAN (Q9UKU0) Long-chain-fatty-acid--CoA ligase 6 (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase 6) (LACS 6) Length = 697 Score = 69.7 bits (169), Expect = 7e-12 Identities = 73/266 (27%), Positives = 110/266 (41%), Gaps = 44/266 (16%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYS--LNSVLLA-GLRAGS 173 KG MLTH +++ + + DV + LPL H++ + SV+ G R G Sbjct: 284 KGAMLTHGNVVADFSGFLKVTESQWAPTCADVHISYLPLAHMFERMVQSVVYCHGGRVG- 342 Query: 174 AMVIMRKFDIGALVELVRAHGITVAPFVPPIV-------------------VEIA---KS 287 + DI L + ++A T+ P VP ++ +E A K Sbjct: 343 ----FFQGDIRLLSDDMKALCPTIFPVVPRLLNRMYDKIFSQANTPLKRWLLEFAAKRKQ 398 Query: 288 PQVTAGDLAS-------------------IRMVMSGAAPMGKELQDAFMAKIPNAVLGQG 410 +V +G + + +RM+++GAAP + A + V +G Sbjct: 399 AEVRSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVY-EG 457 Query: 411 YGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGASLGRNQPGEICIRG 590 YG TE A C P SG G + +K+VD + GEIC+RG Sbjct: 458 YGQTEC---TAGCTFTT--PGDWTSGHVGAPLPCNHIKLVDVEELNYWACKGEGEICVRG 512 Query: 591 EQIMKGYLNDPESTKNTIDKDGWLHT 668 + KGYL DP+ TK +D DGWLHT Sbjct: 513 PNVFKGYLKDPDRTKEALDSDGWLHT 538
>CAIC_SALTY (Q8ZRX4) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 517 Score = 69.7 bits (169), Expect = 7e-12 Identities = 61/225 (27%), Positives = 101/225 (44%), Gaps = 3/225 (1%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV++TH +L + + R +DV + ++P FHI + + AGS V Sbjct: 189 KGVVITHYNLRFAGYYSAW----QIALRDDDVYMTVMPAFHIDCQCTAAMPAFSAGSTFV 244 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKEL 362 ++ K+ A + VR + TV +P ++ + P +R VM + ++ Sbjct: 245 LLEKYSARAFWDQVRKYQATVTECIPMMIRTLMVQPAAPTDRQHHLREVMF-YLNLSEQE 303 Query: 363 QDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDT 542 +D F + +L YGMTE + + + K + S G V + +I D D Sbjct: 304 KDDFTERFGVRLL-TSYGMTET----IVGIIGDRPGDKRRWPSIGRVGFSYEAEIRD-DQ 357 Query: 543 GASLGRNQPGEICIR---GEQIMKGYLNDPESTKNTIDKDGWLHT 668 L + GEICI+ G+ I K Y PE+T ++ +GWLHT Sbjct: 358 NRPLPAGEIGEICIKGIPGKTIFKEYYMQPEATAKALEPEGWLHT 402
>MENE_STAES (Q8CS21) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 474 Score = 67.4 bits (163), Expect = 4e-11 Identities = 54/203 (26%), Positives = 96/203 (47%) Frame = +3 Query: 60 GENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMVIMRKFDIGALVELVRAHGI 239 G +L F + V L +LP++HI L SV+L + G + +++KF ++ ++ + I Sbjct: 163 GCKQSLGFEQNTVWLSVLPIYHISGL-SVILRAVIEGFTVRLVKKFQTDDMLTQIKTYPI 221 Query: 240 TVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKELQDAFMAKIPNAVLGQGYGM 419 T VP + + + L I ++ GA + ++ AF ++P + +GM Sbjct: 222 THMSLVPQTLKWLMDAGLTQPFSLEKI--LLGGAKLSPQLIEQAFAYRLP---VYNSFGM 276 Query: 420 TEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGASLGRNQPGEICIRGEQI 599 TE + L + + K + + G N +KI +P+ GE+ I+GE + Sbjct: 277 TET---CSQFLTASPQMLKERFDTVGKTSENVEVKIKNPNAYGH------GELLIKGENV 327 Query: 600 MKGYLNDPESTKNTIDKDGWLHT 668 M GYL P+ K+T D DG+ T Sbjct: 328 MNGYLY-PKYLKDTFDNDGYFQT 349
>CAIC_ECOLI (P31552) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 522 Score = 67.4 bits (163), Expect = 4e-11 Identities = 62/225 (27%), Positives = 101/225 (44%), Gaps = 3/225 (1%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV++TH +L + R +DV L ++P FHI + +A AG+ V Sbjct: 194 KGVVITHYNLRFAGYYSAW----QCALRDDDVYLTVMPAFHIDCQCTAAMAAFSAGATFV 249 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKEL 362 ++ K+ A V+ + TV +P ++ + P +R VM + ++ Sbjct: 250 LVEKYSARAFWGQVQKYRATVTECIPMMIRTLMVQPPSANDQQHRLREVMF-YLNLSEQE 308 Query: 363 QDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDT 542 +DAF + +L YGMTE + + + K + S G V +I D D Sbjct: 309 KDAFCERFGVRLL-TSYGMTET----IVGIIGDRPGDKRRWPSIGRVGFCYEAEIRD-DH 362 Query: 543 GASLGRNQPGEICIR---GEQIMKGYLNDPESTKNTIDKDGWLHT 668 L + GEICI+ G+ I K Y +P++T ++ DGWLHT Sbjct: 363 NRPLPAGEIGEICIKGIPGKTIFKEYFLNPQATAKVLEADGWLHT 407
>ACSL6_RAT (P33124) Long-chain-fatty-acid--CoA ligase 6 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 6) (LACS 6) (Long-chain-fatty-acid--CoA ligase, brain isozyme) Length = 697 Score = 65.5 bits (158), Expect = 1e-10 Identities = 41/117 (35%), Positives = 57/117 (48%) Frame = +3 Query: 318 IRMVMSGAAPMGKELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCG 497 +RM+++GAAP + A + V +GYG TE A C P SG G Sbjct: 428 VRMIVTGAAPASPTVLGFLRAALGCQVY-EGYGQTEC---TAGCTFTT--PGDWTSGHVG 481 Query: 498 TVVRNAGLKIVDPDTGASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 + +K+VD + GEIC++G + KGYL D + TK +D DGWLHT Sbjct: 482 APLPCNHIKLVDAEELNYWTSKGEGEICVKGPNVFKGYLKDEDRTKEALDSDGWLHT 538
>CAIC_ECOL6 (Q8FLA5) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 522 Score = 65.1 bits (157), Expect = 2e-10 Identities = 59/227 (25%), Positives = 99/227 (43%), Gaps = 5/227 (2%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV++TH +L + R +DV L ++P FHI + +A AG+ V Sbjct: 194 KGVVITHYNLRFAGYYSAW----QCALRDDDVYLTVMPAFHIDCQCTAAMAAFSAGATFV 249 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKEL 362 ++ K+ A V+ + T+ +P ++ + P +R VM + ++ Sbjct: 250 LVEKYSARAFWGQVQKYRATITECIPMMIRTLMVQPLSANDQQHRLREVMF-YLNLSEQE 308 Query: 363 QDAFMAKIPNAVLGQGYGMTE--AGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDP 536 +DAF + +L YGMTE G + + P ++G C + Sbjct: 309 KDAFCERFSVRLL-TSYGMTETIVGIIGDRPGDKRRWPSIGRAGFCYEAE-------IRD 360 Query: 537 DTGASLGRNQPGEICIR---GEQIMKGYLNDPESTKNTIDKDGWLHT 668 D L + GEICI+ G+ I K Y +P++T ++ DGWLHT Sbjct: 361 DHNRPLPAGELGEICIKGVPGKTIFKEYFLNPKATAKVLEADGWLHT 407
>MENE_STAEQ (Q5HNB2) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 474 Score = 64.3 bits (155), Expect = 3e-10 Identities = 53/203 (26%), Positives = 95/203 (46%) Frame = +3 Query: 60 GENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMVIMRKFDIGALVELVRAHGI 239 G +L F + V L +LP++HI L SV+L + G + +++KF ++ ++ + I Sbjct: 163 GCKQSLGFEQNTVWLSVLPIYHISGL-SVILRAVIEGFTVRLVKKFQTDDMLTQIKTYPI 221 Query: 240 TVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKELQDAFMAKIPNAVLGQGYGM 419 T VP + + + L I ++ GA + ++ A ++P + +GM Sbjct: 222 THMSLVPQTLKWLMDAGLTQPFSLEKI--LLGGAKLSPQLIEQALTYRLP---VYNSFGM 276 Query: 420 TEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGASLGRNQPGEICIRGEQI 599 TE + L + + K + + G N +KI +P+ GE+ I+GE + Sbjct: 277 TET---CSQFLTASPQMLKERFDTVGKPSENVEVKIKNPNAYGH------GELLIKGENV 327 Query: 600 MKGYLNDPESTKNTIDKDGWLHT 668 M GYL P+ K+T D DG+ T Sbjct: 328 MNGYLY-PKYLKDTFDNDGYFQT 349
>FADK_ECOLI (P38135) Short-chain-fatty-acid--CoA ligase (EC 6.2.1.-) (Acyl-CoA| synthetase) Length = 548 Score = 64.3 bits (155), Expect = 3e-10 Identities = 54/222 (24%), Positives = 91/222 (40%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGVMLTH +++ S L +DV + PL H + A G+ V Sbjct: 204 KGVMLTHNNILASERAYC----ARLNLTWQDVFMMPAPLGHATGFLHGVTAPFLIGARSV 259 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKEL 362 ++ F A + L+ T P V ++ + DL+++R + G + K++ Sbjct: 260 LLDIFTPDACLALLEQQRCTCMLGATPFVYDLLNVLEKQPADLSALRFFLCGGTTIPKKV 319 Query: 363 QDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDT 542 + L YG TE+ P + L +P + G +K+VD D Sbjct: 320 ARECQQR--GIKLLSVYGSTESSPHAVVNL---DDPLSRFMHTDGYAAAGVEIKVVD-DA 373 Query: 543 GASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 +L GE RG + GY ++PE T +D++GW ++ Sbjct: 374 RKTLPPGCEGEEASRGPNVFMGYFDEPELTARALDEEGWYYS 415
>AAS_PHOLL (Q7N7A9) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 639 Score = 63.2 bits (152), Expect = 7e-10 Identities = 61/220 (27%), Positives = 94/220 (42%), Gaps = 3/220 (1%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV+ +H SL+ +V Q + F D + LPLFH + L L L +GS + Sbjct: 381 KGVVHSHASLLANVEQIKTITD----FNPLDRFMSSLPLFHAFGLTVGLFTPLLSGSRIF 436 Query: 183 IM-RKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKE 359 + + ELV TV + A S D A +R V++G + + Sbjct: 437 LYPNPLHYRVVPELVYECNCTVLLGTSSFLENYAYSAHPY--DFARLRCVIAGIEKLAEN 494 Query: 360 LQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPD 539 + + K +L +GYGMTE PV+A+ P K G+ G ++ +++ Sbjct: 495 TKQIWQDKFGIRIL-EGYGMTECAPVIAL-----NVPMMAKVGTVGRILPAMEFRLI--- 545 Query: 540 TGASLGRNQPGEICIRGEQIMKGYL--NDPESTKNTIDKD 653 G Q G + +RG +MKGYL DP + KD Sbjct: 546 --PIAGIKQGGRLQLRGPNMMKGYLRMEDPNHLEPPAVKD 583
>CAIC_ECO57 (Q8XA34) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 522 Score = 63.2 bits (152), Expect = 7e-10 Identities = 59/225 (26%), Positives = 99/225 (44%), Gaps = 3/225 (1%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV++TH +L + R +DV L ++P FHI + +A AG+ V Sbjct: 194 KGVVITHYNLRFAGYYSAW----QCALRDDDVYLTVMPAFHIDCQCTAAMAAFSAGATFV 249 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKEL 362 ++ K+ A V+ + T+ +P ++ + P +R VM + ++ Sbjct: 250 LVEKYSARAFWGQVQKYRATITECIPMMIRTLMVQPPSANDRQHRLREVMF-YLNLSEQE 308 Query: 363 QDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDT 542 +D F + +L YGMTE + + + K + S G +I D D Sbjct: 309 KDTFCERFGVRLL-TSYGMTET----IVGIIGDRPGDKRRWPSIGRAGFCYDAEIRD-DH 362 Query: 543 GASLGRNQPGEICIR---GEQIMKGYLNDPESTKNTIDKDGWLHT 668 L + GEICI+ G+ I K Y +P++T ++ DGWLHT Sbjct: 363 NRPLPAGEIGEICIKGVPGKTIFKEYFLNPKATAKVLEADGWLHT 407
>MENE_BACSU (P23971) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 486 Score = 62.8 bits (151), Expect = 9e-10 Identities = 56/200 (28%), Positives = 90/200 (45%), Gaps = 1/200 (0%) Frame = +3 Query: 72 NLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMVIMRKFDIGALVELVRAHGITVAP 251 NL ++D L LPLFHI L S L + G +V+ ++F + ++ + H +T+ Sbjct: 179 NLGITEQDRWLIALPLFHISGL-SALFKSVIYGMTVVLHQRFSVSDVLHSINRHEVTMIS 237 Query: 252 FVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKELQDAFMAKIPNAVLGQGYGMTEA- 428 V ++ + + T SIR ++ G P L + K + Q YGMTE Sbjct: 238 AVQTMLASLLEE---TNRCPESIRCILLGGGPAPLPLLEECREK--GFPVFQSYGMTETC 292 Query: 429 GPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGASLGRNQPGEICIRGEQIMKG 608 ++ + F+ E K GS G + + +KI G + GEI ++G +MK Sbjct: 293 SQIVTLSPEFSME----KLGSAGKPLFSCEIKI--ERDGQVCEPYEHGEIMVKGPNVMKS 346 Query: 609 YLNDPESTKNTIDKDGWLHT 668 Y N ES ++GWL T Sbjct: 347 YFN-RESANEASFQNGWLKT 365
>CAIC_SHIFL (Q83MG9) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 522 Score = 62.8 bits (151), Expect = 9e-10 Identities = 57/227 (25%), Positives = 98/227 (43%), Gaps = 5/227 (2%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV++TH +L + R +DV + ++P FHI + +A AG+ V Sbjct: 194 KGVVITHYNLRFAGYYSAW----QCALRDDDVYMTVMPAFHIDCQCTAAMAAFSAGATFV 249 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKEL 362 ++ K+ A + + T+ +P ++ + P +R VM + ++ Sbjct: 250 LVEKYSARAFWGQAQKYRATITECIPMMIRTLMVQPPSANDRQHRLREVMF-YLNLSEQE 308 Query: 363 QDAFMAKIPNAVLGQGYGMTE--AGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDP 536 +DAF + +L YGMTE G + + P ++G C + Sbjct: 309 KDAFCERFGVRLL-TSYGMTETIVGIIGDRPSDKRRWPSIGRAGFCYEAE-------IRD 360 Query: 537 DTGASLGRNQPGEICIR---GEQIMKGYLNDPESTKNTIDKDGWLHT 668 D L + GEICI+ G+ I K Y +P++T ++ DGWLHT Sbjct: 361 DHNRPLPAGEIGEICIKGVPGKTIFKEYFLNPKATAKVLEADGWLHT 407
>MENE_LISIN (Q92AY8) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 467 Score = 62.4 bits (150), Expect = 1e-09 Identities = 59/223 (26%), Positives = 99/223 (44%), Gaps = 1/223 (0%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGVM T+ + S V NL ++D LC +P+FHI L S+++ + G + Sbjct: 152 KGVMQTYENHWWSAVSSV----LNLGLTEKDSWLCAVPIFHISGL-SIMMRSVIYGIPVY 206 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDL-ASIRMVMSGAAPMGKE 359 + FD + +L+ + I+ V ++ + K + G ++R V+ G P K Sbjct: 207 LEEHFDEEKITQLLESGKISTISVVTSMLERLLK---IQGGSYHPNVRTVLLGGGPANKA 263 Query: 360 LQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPD 539 + + + K + L Q +GMTE + + + K GS G + A +KI D Sbjct: 264 VLE--ICKQRDIPLVQSFGMTETA---SQIVTLPPKDALNKIGSSGKALFPAEVKIAD-- 316 Query: 540 TGASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 GEI ++G I GYL++ ++T DGW T Sbjct: 317 ---------DGEILLKGPSITPGYLHNEKATAKAF-IDGWFKT 349
>FAD11_MYCTU (Q10776) Putative fatty-acid--CoA ligase fadD11 (EC 6.2.1.-)| (Acyl-CoA synthetase) Length = 571 Score = 62.0 bits (149), Expect = 2e-09 Identities = 46/141 (32%), Positives = 66/141 (46%), Gaps = 6/141 (4%) Frame = +3 Query: 264 IVVEIAKSPQVTAGDL------ASIRMVMSGAAPMGKELQDAFMAKIPNAVLGQGYGMTE 425 +V E AK+ ++ L +R +SGAAP+ KE AF A I + + +GM+E Sbjct: 276 LVAEWAKADELVLSKLRERLGFGELRWALSGAAPIPKETL-AFFAGI-GIPIAEIWGMSE 333 Query: 426 AGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGASLGRNQPGEICIRGEQIMK 605 C+A A P + G+ G ++ KI + GE +RG +MK Sbjct: 334 LS-----CVATASHPRDGRLGTVGKLLPGLQGKIAED-----------GEYLVRGPLVMK 377 Query: 606 GYLNDPESTKNTIDKDGWLHT 668 GY +P T ID DGWLHT Sbjct: 378 GYRKEPAKTAEAIDSDGWLHT 398
>CAIC_PROSL (Q8GB18) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 518 Score = 62.0 bits (149), Expect = 2e-09 Identities = 61/225 (27%), Positives = 101/225 (44%), Gaps = 3/225 (1%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV++TH +L +A L R++D+ L ++P FHI + L G+ +V Sbjct: 190 KGVVITHYNL--RIAGYYSSWQNAL--REDDIYLTVMPAFHIDCQCTASLPAYSVGATIV 245 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKEL 362 ++ K+ A + + + TV +P ++ P +R VMS KE Sbjct: 246 LLEKYSARASWKQILKYQATVTECIPMMMRTSMAQPVSPDEKQHKLREVMSYLNLADKE- 304 Query: 363 QDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDT 542 +DA + ++ N L +GMTE + L + K + S G +I D Sbjct: 305 KDASIERL-NVRLLTSHGMTET----IVGLIGDRPGDKRRWPSIGRPGFCYQAQIRDKQN 359 Query: 543 GASLGRNQPGEICIRGEQ---IMKGYLNDPESTKNTIDKDGWLHT 668 + GEIC++GE + K Y N P++T+ ++ DGWLHT Sbjct: 360 -QQVPNGVVGEICVKGEAGKTLFKEYYNRPDATEKALEPDGWLHT 403
>MENE_LISMF (Q71YZ5) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 467 Score = 61.2 bits (147), Expect = 3e-09 Identities = 58/223 (26%), Positives = 102/223 (45%), Gaps = 1/223 (0%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV+ T+ + S V NL ++D LC +P+FHI L S+++ + G + Sbjct: 152 KGVVQTYENHWWSAVASV----LNLGLTEKDSWLCAVPIFHISGL-SIMMRSVIYGIPVY 206 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDL-ASIRMVMSGAAPMGKE 359 + FD + +L+ + I+ V ++ + K + +G ++R V+ G P K Sbjct: 207 LEEHFDEEKITQLLESGKISTISVVTSMLERLLK---IHSGSYHPNVRTVLLGGGPASKA 263 Query: 360 LQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPD 539 + + + K + L Q +GMTE + + + K GS G + A +KI D Sbjct: 264 VLE--ICKQRDIPLVQSFGMTETA---SQIVTLPPKDALNKIGSSGKALFPAEVKIAD-- 316 Query: 540 TGASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 GEI ++G I GYL++ ++T+ + DGW T Sbjct: 317 ---------DGEILLKGPSITPGYLHNKKATEASF-VDGWFKT 349
>MENE_LISMO (P58730) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 467 Score = 60.1 bits (144), Expect = 6e-09 Identities = 56/223 (25%), Positives = 101/223 (45%), Gaps = 1/223 (0%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV+ T+ + S V NL ++D LC +P+FHI L S+++ + G + Sbjct: 152 KGVIQTYENHWWSAVASV----LNLGLTEKDSWLCAVPIFHISGL-SIMMRSVIYGIPVY 206 Query: 183 IMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDL-ASIRMVMSGAAPMGKE 359 + FD + +L+ + ++ V ++ + K + G ++R ++ G P K Sbjct: 207 LEEHFDEEKITQLLESGKVSTISVVTSMLERLLK---IHGGSYHPNVRTILLGGGPASKT 263 Query: 360 LQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPD 539 + + + K + L Q +GMTE + + + K GS G + A +KI D Sbjct: 264 VLE--ICKQRDIPLVQSFGMTETA---SQIVTLPPKDALNKIGSSGKALFPAEVKIAD-- 316 Query: 540 TGASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 GEI ++G I GYL++ ++T+ + DGW T Sbjct: 317 ---------DGEILLKGPSITPGYLHNKKATEASF-VDGWFKT 349
>AAS_YERPS (Q667F1) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 718 Score = 59.3 bits (142), Expect = 1e-08 Identities = 55/205 (26%), Positives = 89/205 (43%), Gaps = 1/205 (0%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV+ +H SL+ +V Q + F D + LPLFH + L L L GS + Sbjct: 381 KGVVHSHASLLANVEQIRTIAD----FTPRDRFMSSLPLFHAFGLTVGLFTPLMTGSRVF 436 Query: 183 IM-RKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKE 359 + + ELV TV + A+ D A +R V++GA + + Sbjct: 437 LYPSPLHYRVVPELVYDRNCTVLFGTSTFLGNYARFAH--PYDFARVRYVVAGAEKLAES 494 Query: 360 LQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPD 539 + + K +L +GYG+TE PV+A+ P K + G ++ ++++ Sbjct: 495 TKQIWQDKFGIRIL-EGYGVTECAPVVAI-----NVPMAAKVNTVGRILPGMEARLINVP 548 Query: 540 TGASLGRNQPGEICIRGEQIMKGYL 614 G Q G + +RG IM+GYL Sbjct: 549 -----GIAQGGRLQLRGPNIMRGYL 568
>AAS_YERPE (Q74RZ6) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 718 Score = 59.3 bits (142), Expect = 1e-08 Identities = 55/205 (26%), Positives = 89/205 (43%), Gaps = 1/205 (0%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV+ +H SL+ +V Q + F D + LPLFH + L L L GS + Sbjct: 381 KGVVHSHASLLANVEQIRTIAD----FTPRDRFMSSLPLFHAFGLTVGLFTPLMTGSRVF 436 Query: 183 IM-RKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKE 359 + + ELV TV + A+ D A +R V++GA + + Sbjct: 437 LYPSPLHYRVVPELVYDRNCTVLFGTSTFLGNYARFAH--PYDFARVRYVVAGAEKLAES 494 Query: 360 LQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPD 539 + + K +L +GYG+TE PV+A+ P K + G ++ ++++ Sbjct: 495 TKQIWQDKFGIRIL-EGYGVTECAPVVAI-----NVPMAAKVNTVGRILPGMEARLINVP 548 Query: 540 TGASLGRNQPGEICIRGEQIMKGYL 614 G Q G + +RG IM+GYL Sbjct: 549 -----GIAQGGRLQLRGPNIMRGYL 568
>AAS_ERWCT (Q6D107) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 738 Score = 56.6 bits (135), Expect = 7e-08 Identities = 56/205 (27%), Positives = 89/205 (43%), Gaps = 1/205 (0%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV+ +H SL+ +V Q + F D + LPLFH + L LL L G+ + Sbjct: 381 KGVVHSHDSLLANVEQIRTVAD----FTPGDRFMSALPLFHAFGLTVGLLTPLITGARVF 436 Query: 183 IM-RKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKE 359 + + ELV TV + A+ D A +R V++GA + + Sbjct: 437 LYPSPLHYRIVPELVYDQNCTVLFGTSTFLGNYARFAH--PYDFARLRYVVAGAEKLSET 494 Query: 360 LQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPD 539 + + K +L +GYG+TE PV+A+ P K S G ++ +++ Sbjct: 495 TRQVWQDKFGIRIL-EGYGVTECAPVVAI-----NVPMATKIHSVGLLLPEMESRLITVP 548 Query: 540 TGASLGRNQPGEICIRGEQIMKGYL 614 G + G + +RG IMKGYL Sbjct: 549 -----GITRGGRLQLRGPNIMKGYL 568
>GRSB_BREBE (P0C064) Gramicidin S synthetase 2 (Gramicidin S synthetase II)| [Includes: ATP-dependent proline adenylase (ProA) (Proline activase); ATP-dependent valine adenylase (ValA) (Valine activase); ATP-dependent ornithine adenylase (OrnA) (Ornithine Length = 4449 Score = 55.5 bits (132), Expect = 1e-07 Identities = 53/214 (24%), Positives = 94/214 (43%), Gaps = 3/214 (1%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGVM+ HR++I V +N N +ED + +L + L G+ + Sbjct: 1661 KGVMVEHRNVIRLV------KNTNYVQVREDDRIIQTGAIGFDALTFEVFGSLLHGAELY 1714 Query: 183 IMRK---FDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMG 353 + K D L + ++A+ IT+ P+ ++++ + L S+ ++ G A Sbjct: 1715 PVTKDVLLDAEKLHKFLQANQITIMWLTSPLFNQLSQGTEEMFAGLRSL--IVGGDALSP 1772 Query: 354 KELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVD 533 K + + K PN + GYG TE + C KE + G + N+ + I+D Sbjct: 1773 KHINNV-KRKCPNLTMWNGYGPTE-NTTFSTCFLIDKE--YDDNIPIGKAISNSTVYIMD 1828 Query: 534 PDTGASLGRNQPGEICIRGEQIMKGYLNDPESTK 635 G PGE+C+ G+ + +GY+N P T+ Sbjct: 1829 R-YGQLQPVGVPGELCVGGDGVARGYMNQPALTE 1861 Score = 42.7 bits (99), Expect = 0.001 Identities = 55/220 (25%), Positives = 95/220 (43%), Gaps = 10/220 (4%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGVM+ H+S+I + + + F D L + F + L A + AG+ V Sbjct: 3743 KGVMIEHQSIINCLQWRKE----EYEFGPGDTALQVFS-FAFDGFVASLFAPILAGATSV 3797 Query: 183 IMRKF---DIGALVELVRAHGITVAPFVPPI---VVEIAKSPQVTAGDLASIRMVMSGAA 344 + ++ D AL +L+ + IT VP + +++++ S DL ++R V G Sbjct: 3798 LPKEEEAKDPVALKKLIASEEITHYYGVPSLFSAILDVSSSK-----DLQNLRCVTLGGE 3852 Query: 345 PMGKELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLK 524 + ++ K + YG TE V + E + + G + N + Sbjct: 3853 KLPAQIVKKIKEKNKEIEVNNEYGPTENSVVTTIMRDIQVE----QEITIGCPLSNVDVY 3908 Query: 525 IVDPDTGASLGRNQP----GEICIRGEQIMKGYLNDPEST 632 IV+ + + QP GE+CI G+ + +GYLN PE T Sbjct: 3909 IVNCNH-----QLQPVGVVGELCIGGQGLARGYLNKPELT 3943
>GRSB_ANEMI (P0C063) Gramicidin S synthetase 2 (Gramicidin S synthetase II)| [Includes: ATP-dependent proline adenylase (ProA) (Proline activase); ATP-dependent valine adenylase (ValA) (Valine activase); ATP-dependent ornithine adenylase (OrnA) (Ornithine Length = 4450 Score = 55.5 bits (132), Expect = 1e-07 Identities = 53/214 (24%), Positives = 94/214 (43%), Gaps = 3/214 (1%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGVM+ HR++I V +N N +ED + +L + L G+ + Sbjct: 1661 KGVMVEHRNVIRLV------KNTNYVQVREDDRIIQTGAIGFDALTFEVFGSLLHGAELY 1714 Query: 183 IMRK---FDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMG 353 + K D L + ++A+ IT+ P+ ++++ + L S+ ++ G A Sbjct: 1715 PVTKDVLLDAEKLHKFLQANQITIMWLTSPLFNQLSQGTEEMFAGLRSL--IVGGDALSP 1772 Query: 354 KELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVD 533 K + + K PN + GYG TE + C KE + G + N+ + I+D Sbjct: 1773 KHINNV-KRKCPNLTMWNGYGPTE-NTTFSTCFLIDKE--YDDNIPIGKAISNSTVYIMD 1828 Query: 534 PDTGASLGRNQPGEICIRGEQIMKGYLNDPESTK 635 G PGE+C+ G+ + +GY+N P T+ Sbjct: 1829 R-YGQLQPVGVPGELCVGGDGVARGYMNQPALTE 1861 Score = 42.7 bits (99), Expect = 0.001 Identities = 55/220 (25%), Positives = 95/220 (43%), Gaps = 10/220 (4%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGVM+ H+S+I + + + F D L + F + L A + AG+ V Sbjct: 3744 KGVMIEHQSIINCLQWRKE----EYEFGPGDTALQVFS-FAFDGFVASLFAPILAGATSV 3798 Query: 183 IMRKF---DIGALVELVRAHGITVAPFVPPI---VVEIAKSPQVTAGDLASIRMVMSGAA 344 + ++ D AL +L+ + IT VP + +++++ S DL ++R V G Sbjct: 3799 LPKEEEAKDPVALKKLIASEEITHYYGVPSLFSAILDVSSSK-----DLQNLRCVTLGGE 3853 Query: 345 PMGKELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLK 524 + ++ K + YG TE V + E + + G + N + Sbjct: 3854 KLPAQIVKKIKEKNKEIEVNNEYGPTENSVVTTIMRDIQVE----QEITIGRPLSNVDVY 3909 Query: 525 IVDPDTGASLGRNQP----GEICIRGEQIMKGYLNDPEST 632 IV+ + + QP GE+CI G+ + +GYLN PE T Sbjct: 3910 IVNCNH-----QLQPVGVVGELCIGGQGLARGYLNKPELT 3944
>PPS3_BACSU (P39847) Peptide synthetase 3| Length = 2555 Score = 55.1 bits (131), Expect = 2e-07 Identities = 50/220 (22%), Positives = 88/220 (40%), Gaps = 3/220 (1%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV + HR ++ + G ++D+++ S+ + L SA + Sbjct: 620 KGVAVEHRQAVSFLT----GMQHQFRLSEDDIVMVKTSFSFDASVWQLFWWALSGASAYL 675 Query: 183 IMRKF--DIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTA-GDLASIRMVMSGAAPMG 353 + + D +V+ + +T A F+P ++ ++ D S++ V +G P+ Sbjct: 676 LPPGWEKDSALIVQAIHQENVTTAHFIPAMLNSFLDQAEIERLSDRTSLKRVFAGGEPLA 735 Query: 354 KELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVD 533 F + +P L GYG TEA A + + G V A L ++D Sbjct: 736 PRTAARFASVLPQVSLIHGYGPTEATVDAAFYVLDPERDRDRLRIPIGKPVPGARLYVLD 795 Query: 534 PDTGASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKD 653 P A GE+ I G + +GYLN P T+ +D Sbjct: 796 PHL-AVQPSGVAGELYIAGAGVARGYLNRPALTEERFLED 834 Score = 36.6 bits (83), Expect = 0.070 Identities = 52/216 (24%), Positives = 86/216 (39%), Gaps = 5/216 (2%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPN-LYFRKEDVLLCLLPL-FHIYSLNSVLLAGLRAGSA 176 KGVM+ RS+I V +N N + F ED LL + F + S + L G+A Sbjct: 1661 KGVMIEQRSVIRLV------KNSNYITFTPEDRLLMTSSIGFDVGSFE--IFGPLLNGAA 1712 Query: 177 MVIMRK---FDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAP 347 + + + D L + GIT + + + + T + ++ ++ G Sbjct: 1713 LHLSDQQTFLDSHQLKRYIEHQGITTIWLTSSLFNHLTEQNEQT---FSQLKHLIIGGEA 1769 Query: 348 MGKELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKI 527 + + P + GYG TE + CL K S G V N+ I Sbjct: 1770 LSPSHVNRIRNVCPEVSIWNGYGPTE-NTTFSTCLHIQKT--YELSIPIGRPVGNSTAFI 1826 Query: 528 VDPDTGASLGRNQPGEICIRGEQIMKGYLNDPESTK 635 ++ G GE+C+ G+ + +GYL P+ TK Sbjct: 1827 LN-QWGVLQPVGAVGELCVGGDGVARGYLGRPDLTK 1861
>PPS1_BACSU (P39845) Peptide synthetase 1| Length = 2561 Score = 54.7 bits (130), Expect = 2e-07 Identities = 50/220 (22%), Positives = 88/220 (40%), Gaps = 3/220 (1%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV + HR ++ + G ++D+++ S+ + L SA + Sbjct: 614 KGVAVEHRQAVSFLT----GMQHQFPLSEDDIVMVKTSFSFDASVWQLFWWSLSGASAYL 669 Query: 183 IMRKF--DIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTA-GDLASIRMVMSGAAPMG 353 + + D +V+ + +T A F+P ++ ++ D S++ V +G P+ Sbjct: 670 LPPGWEKDSALIVQAIHQENVTTAHFIPAMLNSFLDQAEIERLSDRTSLKRVFAGGEPLA 729 Query: 354 KELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVD 533 F + +P L GYG TEA A + + G V A L ++D Sbjct: 730 PRTAARFASVLPQVSLIHGYGPTEATVDAAFYVLDPERDRDRLRIPIGKPVPGARLYVLD 789 Query: 534 PDTGASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKD 653 P A GE+ I G + +GYLN P T+ +D Sbjct: 790 PHL-AVQPSGVAGELYIAGAGVARGYLNRPALTEERFLED 828
>TYCB_BREPA (O30408) Tyrocidine synthetase 2 (Tyrocidine synthetase II)| [Includes: ATP-dependent proline adenylase (ProA) (Proline activase); ATP-dependent phenylalanine adenylase (PheA) (Phenylalanine activase); ATP-dependent D-phenylalanine adenylase (D Length = 3587 Score = 54.3 bits (129), Expect = 3e-07 Identities = 60/213 (28%), Positives = 92/213 (43%), Gaps = 3/213 (1%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGVM+ HR ++ SV D ++ ++ L L F ++L L + +GS +V Sbjct: 1662 KGVMVEHRGIVNSVTWNRDEFALSV---RDSGTLSLSFAFDAFALTFFTL--IVSGSTVV 1716 Query: 183 IMRKFDIG---ALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMG 353 +M + AL L+ A + FVP + I + T D+ SI+ VM G + Sbjct: 1717 LMPDHEAKDPIALRNLIAAWECSYVVFVPSMFQAILECS--TPADIRSIQAVMLGGEKLS 1774 Query: 354 KELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVD 533 +L A P + YG TE+ V+A L + + + G + N + IVD Sbjct: 1775 PKLVQLCKAMHPQMSVMNAYGPTESS-VMATYLRDTQPDQPI---TIGRPIANTAIYIVD 1830 Query: 534 PDTGASLGRNQPGEICIRGEQIMKGYLNDPEST 632 L GEICI G + +GY PE T Sbjct: 1831 QHHQL-LPVGVVGEICIGGHGLARGYWKKPELT 1862 Score = 45.8 bits (107), Expect = 1e-04 Identities = 40/145 (27%), Positives = 61/145 (42%) Frame = +3 Query: 198 DIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKELQDAFM 377 D E VR + IT P + + + S+R +++ + L D + Sbjct: 2763 DFQRFAEYVRDNAITFLTLPPTYAIYLEPE------QVPSLRTLITAGSASSVALVDKWK 2816 Query: 378 AKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGASLG 557 K+ GYG TE+ + A EP V++ + G ++N L IVD D Sbjct: 2817 EKVTYV---NGYGPTESTVCATLWKAKPDEP--VETITIGKPIQNTKLYIVD-DQLQLKA 2870 Query: 558 RNQPGEICIRGEQIMKGYLNDPEST 632 Q GE+CI G + +GY N PE T Sbjct: 2871 PGQMGELCISGLSLARGYWNRPELT 2895
>AAS_SALTY (Q8ZMA4) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 719 Score = 53.5 bits (127), Expect = 6e-07 Identities = 51/205 (24%), Positives = 88/205 (42%), Gaps = 1/205 (0%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV+ +H+S++ +V Q + F D + LPLFH + L L L G+ + Sbjct: 381 KGVVHSHKSILANVEQIKTIAD----FTANDRFMSALPLFHSFGLTVGLFTPLLTGAEVF 436 Query: 183 IMRK-FDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKE 359 + + ELV TV + A+ D +R V++GA + + Sbjct: 437 LYPSPLHYRIVPELVYDRNCTVLFGTSTFLGNYARF--ANPYDFYRLRYVVAGAEKLQES 494 Query: 360 LQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPD 539 + + K +L +GYG+TE PV+++ P K G+ G ++ +++ Sbjct: 495 TKQLWQDKFGLRIL-EGYGVTECAPVVSI-----NVPMAAKPGTVGRILPGMDARLL--- 545 Query: 540 TGASLGRNQPGEICIRGEQIMKGYL 614 A G G + ++G IM GYL Sbjct: 546 --AVPGIENGGRLQLKGPNIMNGYL 568
>AAS_SALTI (Q8Z406) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 719 Score = 53.5 bits (127), Expect = 6e-07 Identities = 51/205 (24%), Positives = 88/205 (42%), Gaps = 1/205 (0%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV+ +H+S++ +V Q + F D + LPLFH + L L L G+ + Sbjct: 381 KGVVHSHKSILANVEQIKTIAD----FTANDRFMSALPLFHSFGLTVGLFTPLLTGAEVF 436 Query: 183 IMRK-FDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKE 359 + + ELV TV + A+ D +R V++GA + + Sbjct: 437 LYPSPLHYRIVPELVYDRNCTVLFGTSTFLGNYARF--ANPYDFYRLRYVVAGAEKLQES 494 Query: 360 LQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPD 539 + + K +L +GYG+TE PV+++ P K G+ G ++ +++ Sbjct: 495 TKQLWQDKFGLRIL-EGYGVTECAPVVSI-----NVPMAAKPGTVGRILPGMDARLL--- 545 Query: 540 TGASLGRNQPGEICIRGEQIMKGYL 614 A G G + ++G IM GYL Sbjct: 546 --AVPGIENGGRLQLKGPNIMNGYL 568
>AAS_SALPA (Q5PEN7) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 719 Score = 53.5 bits (127), Expect = 6e-07 Identities = 51/205 (24%), Positives = 88/205 (42%), Gaps = 1/205 (0%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV+ +H+S++ +V Q + F D + LPLFH + L L L G+ + Sbjct: 381 KGVVHSHKSILANVEQIKTIAD----FTANDRFMSALPLFHSFGLTVGLFTPLLTGAEVF 436 Query: 183 IMRK-FDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKE 359 + + ELV TV + A+ D +R V++GA + + Sbjct: 437 LYPSPLHYRIVPELVYDRNCTVLFGTSTFLGNYARF--ANPYDFYRLRYVVAGAEKLQES 494 Query: 360 LQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPD 539 + + K +L +GYG+TE PV+++ P K G+ G ++ +++ Sbjct: 495 TKQLWQDKFGLRIL-EGYGVTECAPVVSI-----NVPMAAKPGTVGRILPGMDARLL--- 545 Query: 540 TGASLGRNQPGEICIRGEQIMKGYL 614 A G G + ++G IM GYL Sbjct: 546 --AVPGIENGGRLQLKGPNIMNGYL 568
>AAS_ECOLI (P31119) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 719 Score = 53.5 bits (127), Expect = 6e-07 Identities = 50/205 (24%), Positives = 88/205 (42%), Gaps = 1/205 (0%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV+ +H+S++ +V Q + F D + LPLFH + L L L G+ + Sbjct: 381 KGVVHSHKSILANVEQIKTIAD----FTTNDRFMSALPLFHSFGLTVGLFTPLLTGAEVF 436 Query: 183 IMRK-FDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKE 359 + + ELV TV + A+ D +R V++GA + + Sbjct: 437 LYPSPLHYRIVPELVYDRSCTVLFGTSTFLGHYARF--ANPYDFYRLRYVVAGAEKLQES 494 Query: 360 LQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPD 539 + + K +L +GYG+TE PV+++ P K G+ G ++ +++ Sbjct: 495 TKQLWQDKFGLRIL-EGYGVTECAPVVSI-----NVPMAAKPGTVGRILPGMDARLLSVP 548 Query: 540 TGASLGRNQPGEICIRGEQIMKGYL 614 G + G + ++G IM GYL Sbjct: 549 -----GIEEGGRLQLKGPNIMNGYL 568
>AAS_ECOL6 (Q8FEA6) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 719 Score = 53.5 bits (127), Expect = 6e-07 Identities = 50/205 (24%), Positives = 88/205 (42%), Gaps = 1/205 (0%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV+ +H+S++ +V Q + F D + LPLFH + L L L G+ + Sbjct: 381 KGVVHSHKSILANVEQIKTIAD----FTTNDRFMSALPLFHSFGLTVGLFTPLLTGAEVF 436 Query: 183 IMRK-FDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKE 359 + + ELV TV + A+ D +R V++GA + + Sbjct: 437 LYPSPLHYRIVPELVYDRSCTVLFGTSTFLGHYARF--ANPYDFYRLRYVVAGAEKLQES 494 Query: 360 LQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPD 539 + + K +L +GYG+TE PV+++ P K G+ G ++ +++ Sbjct: 495 TKQLWQDKFGLRIL-EGYGVTECAPVVSI-----NVPMAAKPGTVGRILPGMDARLLSVP 548 Query: 540 TGASLGRNQPGEICIRGEQIMKGYL 614 G + G + ++G IM GYL Sbjct: 549 -----GIEEGGRLQLKGPNIMNGYL 568
>AAS_ECO57 (Q8X6J8) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 719 Score = 53.5 bits (127), Expect = 6e-07 Identities = 50/205 (24%), Positives = 88/205 (42%), Gaps = 1/205 (0%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV+ +H+S++ +V Q + F D + LPLFH + L L L G+ + Sbjct: 381 KGVVHSHKSILANVEQIKTIAD----FTTNDRFMSALPLFHSFGLTVGLFTPLLTGAEVF 436 Query: 183 IMRK-FDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKE 359 + + ELV TV + A+ D +R V++GA + + Sbjct: 437 LYPSPLHYRIVPELVYDRSCTVLFGTSTFLGHYARF--ANPYDFYRLRYVVAGAEKLQES 494 Query: 360 LQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPD 539 + + K +L +GYG+TE PV+++ P K G+ G ++ +++ Sbjct: 495 TKQLWQDKFGLRIL-EGYGVTECAPVVSI-----NVPMAAKPGTVGRILPGMDARLLSVP 548 Query: 540 TGASLGRNQPGEICIRGEQIMKGYL 614 G + G + ++G IM GYL Sbjct: 549 -----GIEEGGRLQLKGPNIMNGYL 568
>DLTA_LISMF (Q721J2) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 510 Score = 52.8 bits (125), Expect = 9e-07 Identities = 33/105 (31%), Positives = 49/105 (46%) Frame = +3 Query: 318 IRMVMSGAAPMGKELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCG 497 IR + G + K+ + + P+AV+ YG TEA + + S G Sbjct: 269 IRFLFCGEV-LAKKTASELLNRFPDAVIYNTYGPTEATVAVTQVKVTREVIDAYPSLPLG 327 Query: 498 TVVRNAGLKIVDPDTGASLGRNQPGEICIRGEQIMKGYLNDPEST 632 + + L IVD +TG L + GEI + G + KGYLN+PE T Sbjct: 328 VIKPDMRLHIVDQETGEVLPEGEKGEIVLIGASVSKGYLNEPEKT 372
>BACC_BACLI (O68008) Bacitracin synthetase 3 (BA3) [Includes: ATP-dependent| isoleucine adenylase (IleA) (Isoleucine activase); ATP-dependent D-phenylalanine adenylase (D-PheA) (D-phenylalanine activase); ATP-dependent histidine adenylase (HisA) (Histidine Length = 6359 Score = 52.4 bits (124), Expect = 1e-06 Identities = 54/218 (24%), Positives = 93/218 (42%), Gaps = 8/218 (3%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDV------LLCLLPLFHIYSLNSVLLAGLR 164 KGVM+ H+S++ + LY+RK+ +P F S + L Sbjct: 3155 KGVMVNHQSIVNT-----------LYWRKQSYGYSTADATLQVPSFSFDSSVEDIFTTLI 3203 Query: 165 AGSAMVIMRKFDIGA--LVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSG 338 +G+ +V++R + ++ ++R H T VP + + + + DL + + G Sbjct: 3204 SGAKLVLIRDLRMNPREIIGVLRTHKATNLLAVPSFYLNLLDTIEQPLDDLRFVTVAGEG 3263 Query: 339 AAPMGKELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAG 518 + L K+PN L YG TE V + K+ KV G + N Sbjct: 3264 ---FNESLIRQHFEKLPNVKLFNEYGPTE-NSVCSTRGELRKDDEKVV---IGRPISNHK 3316 Query: 519 LKIVDPDTGASLGRNQPGEICIRGEQIMKGYLNDPEST 632 + I++ + L PGE+C+ GE + +GYLN P+ T Sbjct: 3317 VYILNHNQQL-LPLGTPGELCLSGEGLARGYLNRPDLT 3353 Score = 49.3 bits (116), Expect = 1e-05 Identities = 54/222 (24%), Positives = 95/222 (42%), Gaps = 11/222 (4%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLL----CLLPLFHIYSLN-SVLLAGLRA 167 KGV + H +++ N +F KE L +L + + L + + + L + Sbjct: 4188 KGVFVRHGNVV----------NYTTWFMKEAGLTENDKAMLVSSYAFDLGYTSIFSALLS 4237 Query: 168 GSAMVIMRK---FDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGD-LASIRMVMS 335 GS + I RK + ++ ++ +GIT P + P +A A++R+V+ Sbjct: 4238 GSELHIARKECYTNAHRALKYIKENGITYIKLTPSLFNIFVNDPGFSAEKPCATLRLVVL 4297 Query: 336 GAAPMGKELQDAFMAKIPNAVLGQGYGMTEA--GPVLAMCLAFAKEPFKVKSGSCGTVVR 509 G + + F + P+ V+ YG TE G V + + FK + GT + Sbjct: 4298 GGEMINTRDVETFYNQYPDHVVMNHYGPTETTIGSVFKVIDPEHLDSFK-ECPVIGTPIH 4356 Query: 510 NAGLKIVDPDTGASLGRNQPGEICIRGEQIMKGYLNDPESTK 635 N ++D + L GE+CI G + GY+N P+ TK Sbjct: 4357 NTNAYVLDENMKL-LPEGVYGELCIAGAGVTGGYVNRPDETK 4397 Score = 43.9 bits (102), Expect = 4e-04 Identities = 54/217 (24%), Positives = 91/217 (41%), Gaps = 7/217 (3%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV+ H S V +N N ED + L + + L G+++V Sbjct: 615 KGVVTPHYSAARVV------KNTNYIDITEDDAILQLSNYSFDGSVFDIFGALLNGASLV 668 Query: 183 IMRK---FDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMG 353 ++ K + L E+++ ++V + +A + G LA +R + G G Sbjct: 669 LIEKETVLNTHELAEVIKKEQVSVMFITTALFNTLA---DINIGCLAKLRKIFLG----G 721 Query: 354 KELQDAFMAKIPNAV----LGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGL 521 + + K+ N V L YG TE+ V A + + ++ G+ + N + Sbjct: 722 ERASIPHVRKVLNHVGRDKLIHVYGPTES-TVYATYYFINEIDDEAETIPIGSPLANTSV 780 Query: 522 KIVDPDTGASLGRNQPGEICIRGEQIMKGYLNDPEST 632 I+D + G L PGE+CI G+ + KGYLN E T Sbjct: 781 LIMD-EAGKLLPIGVPGELCIAGDGLSKGYLNREELT 816 Score = 43.5 bits (101), Expect = 6e-04 Identities = 41/169 (24%), Positives = 77/169 (45%), Gaps = 7/169 (4%) Frame = +3 Query: 147 LLAGLRAGSAMVIMRKFDI---GALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLAS 317 + L AGSA+V+ R+ ++ L +R + IT A +PP V+++ + L + Sbjct: 1699 IFPALAAGSALVLGRQEEMMPGQPLTSFLRQYNITHAT-LPPTVLDV-----LNESGLEN 1752 Query: 318 IRMVMSGAAPMGKELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGS-- 491 +++++S + +EL + N + YG TE +C + GS Sbjct: 1753 LKVIVSAGSACSEELAKRWSG---NRLFINAYGPTET----TVCATAG-----IYEGSGR 1800 Query: 492 --CGTVVRNAGLKIVDPDTGASLGRNQPGEICIRGEQIMKGYLNDPEST 632 G+ + N + ++D + + GE+C+ G + +GYLN PE T Sbjct: 1801 PHIGSPIANTNVYVLDQNQ-KPVPTGVVGELCVGGMSLARGYLNRPELT 1848
>AAS_SHIFL (Q83JV7) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 719 Score = 52.4 bits (124), Expect = 1e-06 Identities = 49/205 (23%), Positives = 88/205 (42%), Gaps = 1/205 (0%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV+ +H+S++ +V Q + F D + LPLFH + L L L G+ + Sbjct: 381 KGVVHSHKSILANVEQIKTIAD----FTTNDRFMSALPLFHSFGLTVGLFTPLLTGAEVF 436 Query: 183 IMRK-FDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKE 359 + + +LV TV + A+ D +R V++GA + + Sbjct: 437 LYPSPLHYRIVPDLVYDRSCTVLFGTSTFLGHYARF--ANPYDFYRLRYVVAGAEKLQES 494 Query: 360 LQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPD 539 + + K +L +GYG+TE PV+++ P K G+ G ++ +++ Sbjct: 495 TKQLWQDKFGLRIL-EGYGVTECAPVVSI-----NVPMAAKPGTVGRILPGMDARLLSVP 548 Query: 540 TGASLGRNQPGEICIRGEQIMKGYL 614 G + G + ++G IM GYL Sbjct: 549 -----GIEEGGRLQLKGPNIMNGYL 568
>MENE_STAAR (Q6GFR0) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 492 Score = 52.0 bits (123), Expect = 2e-06 Identities = 48/191 (25%), Positives = 84/191 (43%) Frame = +3 Query: 60 GENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMVIMRKFDIGALVELVRAHGI 239 G +L F ++ L +LP++HI L SVLL + G + I+ KF+ ++ +++ I Sbjct: 192 GCKESLGFDRDTNWLSVLPIYHISGL-SVLLRAVIEGFTVRIVDKFNAEQILTMIKNERI 250 Query: 240 TVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKELQDAFMAKIPNAVLGQGYGM 419 T VP + + + DL I ++ GA ++ A +P + +GM Sbjct: 251 THISLVPQTLNWLMQQGLHEPYDLQKI--LLGGAKLSASMIETALQYNLP---IYNSFGM 305 Query: 420 TEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGASLGRNQPGEICIRGEQI 599 TE + L E + + G N +KI +P+ + GE+ I+G + Sbjct: 306 TET---CSQFLTATPEMLHARPDTVGMPSANVDVKIKNPN------KKGHGELMIKGANV 356 Query: 600 MKGYLNDPEST 632 M GYL + T Sbjct: 357 MNGYLYPTDLT 367
>LCF3_YEAST (P39002) Long-chain-fatty-acid--CoA ligase 3 (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase 3) (Fatty acid activator 3) Length = 694 Score = 52.0 bits (123), Expect = 2e-06 Identities = 61/267 (22%), Positives = 100/267 (37%), Gaps = 45/267 (16%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSL---------NSVLLA 155 KGV+LTH ++++ +A G N + D +L LPL HI+ L N +L Sbjct: 278 KGVVLTHYNIVSGIAGV--GHNVFGWIGSTDRVLSFLPLAHIFELVFEFEAFYWNGILGY 335 Query: 156 GLRAGSAMVIMRK-------------FDIGALVELVRAHGITVAPFVPPIVVEI------ 278 G R + A+ E VR + + P++ +I Sbjct: 336 GSVKTLTNTSTRNCKGDLVEFKPTIMIGVAAVWETVRKAILEKISDLTPVLQKIFWSAYS 395 Query: 279 -----------------AKSPQVTAGDLASIRMVMSGAAPMGKELQDAFMAKIPNAVLGQ 407 K Q T G L + +M+G + + + Q F + ++G Sbjct: 396 MKEKSVPCTGFLSRMVFKKVRQATGGHL---KYIMNGGSAISIDAQKFFSIVLCPMIIG- 451 Query: 408 GYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGASLGRNQPGEICIR 587 YG+TE + A EP + G G +V + K+VD +N GE+ ++ Sbjct: 452 -YGLTET-----VANACVLEPDHFEYGIVGDLVGSVTAKLVDVKDLGYYAKNNQGELLLK 505 Query: 588 GEQIMKGYLNDPESTKNTIDKDGWLHT 668 G + Y +P T + DGW T Sbjct: 506 GAPVCSEYYKNPIETAVSFTYDGWFRT 532
>DLTA_LISMO (Q8Y8D4) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 510 Score = 51.6 bits (122), Expect = 2e-06 Identities = 30/95 (31%), Positives = 45/95 (47%) Frame = +3 Query: 348 MGKELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKI 527 + K+ + + P+AV+ YG TEA + + S G + + L I Sbjct: 278 LAKKTASELLDRFPDAVIYNTYGPTEATVAVTQVKVTREIIDAYPSLPLGVIKPDMRLHI 337 Query: 528 VDPDTGASLGRNQPGEICIRGEQIMKGYLNDPEST 632 VD +TG L + GEI + G + KGYLN+PE T Sbjct: 338 VDQETGEVLPEGEKGEIVLIGASVSKGYLNEPEKT 372
>DLTA_LISIN (Q92D47) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 510 Score = 51.6 bits (122), Expect = 2e-06 Identities = 30/95 (31%), Positives = 45/95 (47%) Frame = +3 Query: 348 MGKELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKI 527 + K+ + + P+AV+ YG TEA + + S G + + L I Sbjct: 278 LAKKTASELLDRFPDAVIYNTYGPTEATVAVTQVKVTRELIDAYPSLPLGVIKPDMRLHI 337 Query: 528 VDPDTGASLGRNQPGEICIRGEQIMKGYLNDPEST 632 VD +TG L + GEI + G + KGYLN+PE T Sbjct: 338 VDQETGEILPEGEKGEIILIGASVSKGYLNEPEKT 372
>MENE_LACLA (Q9CHK3) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 451 Score = 51.2 bits (121), Expect = 3e-06 Identities = 51/219 (23%), Positives = 94/219 (42%), Gaps = 11/219 (5%) Frame = +3 Query: 42 VAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMVIMRKFDIGALVEL 221 ++ V L D L +LP+FH+ L S+++ L ++ ++ KFD L+E+ Sbjct: 155 ISNHVKASKETLGAYDNDNWLVILPMFHVSGL-SIIMRTLYNATSATVVDKFDENQLLEM 213 Query: 222 VRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGA----APMGKELQDAFMAKIP 389 + + I + VP ++ IA ++R+++ G P+ K+ Q+ + Sbjct: 214 INSGKINMVSLVPTLLTRIADKLHSN-----NLRLILLGGEFIPQPLIKKCQELGLP--- 265 Query: 390 NAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGASLGRNQP 569 + + YGMTE+ + + F F K+ S G + ++I D Sbjct: 266 ---IYKTYGMTES---FSQSVTFNILDFPDKTSSVGRPLPGVEIEIRQADLAG------V 313 Query: 570 GEICIRGEQIMKGYLND-PESTK------NTIDKDGWLH 665 GEI ++ +MK YL P T +D DG+L+ Sbjct: 314 GEIWLKSPMLMKAYLGQKPYGTAFETGDIGYLDTDGFLY 352
>LCF1_YEAST (P30624) Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase 1) (Fatty acid activator 1) Length = 700 Score = 50.8 bits (120), Expect = 4e-06 Identities = 60/270 (22%), Positives = 106/270 (39%), Gaps = 48/270 (17%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNL--YFRKEDVLLCLLPLFHIYSLNSVLLA---GLRA 167 KGV+L H +++ V G + N+ + D ++C LPL HI+ L LL+ G Sbjct: 278 KGVVLKHSNVVAGVG----GASLNVLKFVGNTDRVICFLPLAHIFELVFELLSFYWGACI 333 Query: 168 GSAMVI-------------MRKFD------IGALVELVRA---HGITVAPFVPPIVVEIA 281 G A V +++F + A+ E VR + I PF+ + A Sbjct: 334 GYATVKTLTSSSVRNCQGDLQEFKPTIMVGVAAVWETVRKGILNQIDNLPFLTKKIFWTA 393 Query: 282 KSPQVTAGDL---------------------ASIRMVMSGAAPMGKELQDAFMAKIPNAV 398 + ++ L +R +++G +P+ ++ Q+ I + Sbjct: 394 YNTKLNMQRLHIPGGGALGNLVFKKIRTATGGQLRYLLNGGSPISRDAQEFITNLICPML 453 Query: 399 LGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGASLGRNQPGEI 578 +G YG+TE + +P + G G + +K+VD + +N GE+ Sbjct: 454 IG--YGLTETCASTTIL-----DPANFELGVAGDLTGCVTVKLVDVEELGYFAKNNQGEV 506 Query: 579 CIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 I G + Y + E T + DGW T Sbjct: 507 WITGANVTPEYYKNEEETSQALTSDGWFKT 536
>MENE_STAAN (P63526) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 492 Score = 49.7 bits (117), Expect = 8e-06 Identities = 47/191 (24%), Positives = 84/191 (43%) Frame = +3 Query: 60 GENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMVIMRKFDIGALVELVRAHGI 239 G +L F ++ L +LP++HI L SVLL + G + I+ KF+ ++ +++ I Sbjct: 192 GCKESLGFDRDTNWLSVLPIYHISGL-SVLLRAVIEGFTVRIVDKFNAEQILTMIKNERI 250 Query: 240 TVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKELQDAFMAKIPNAVLGQGYGM 419 T VP + + + +L I ++ GA ++ A +P + +GM Sbjct: 251 THISLVPQTLNWLMQQGLHEPYNLQKI--LLGGAKLSATMIETALQYNLP---IYNSFGM 305 Query: 420 TEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGASLGRNQPGEICIRGEQI 599 TE + L E + + G N +KI +P+ + GE+ I+G + Sbjct: 306 TET---CSQFLTATPEMLHARPDTVGMPSANVDVKIKNPN------KEGHGELMIKGANV 356 Query: 600 MKGYLNDPEST 632 M GYL + T Sbjct: 357 MNGYLYPTDLT 367
>MENE_STAAM (P63525) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 492 Score = 49.7 bits (117), Expect = 8e-06 Identities = 47/191 (24%), Positives = 84/191 (43%) Frame = +3 Query: 60 GENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMVIMRKFDIGALVELVRAHGI 239 G +L F ++ L +LP++HI L SVLL + G + I+ KF+ ++ +++ I Sbjct: 192 GCKESLGFDRDTNWLSVLPIYHISGL-SVLLRAVIEGFTVRIVDKFNAEQILTMIKNERI 250 Query: 240 TVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKELQDAFMAKIPNAVLGQGYGM 419 T VP + + + +L I ++ GA ++ A +P + +GM Sbjct: 251 THISLVPQTLNWLMQQGLHEPYNLQKI--LLGGAKLSATMIETALQYNLP---IYNSFGM 305 Query: 420 TEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGASLGRNQPGEICIRGEQI 599 TE + L E + + G N +KI +P+ + GE+ I+G + Sbjct: 306 TET---CSQFLTATPEMLHARPDTVGMPSANVDVKIKNPN------KEGHGELMIKGANV 356 Query: 600 MKGYLNDPEST 632 M GYL + T Sbjct: 357 MNGYLYPTDLT 367
>PPS2_BACSU (P39846) Peptide synthetase 2| Length = 2560 Score = 49.7 bits (117), Expect = 8e-06 Identities = 62/226 (27%), Positives = 96/226 (42%), Gaps = 6/226 (2%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLN-SV--LLAGLRAGS 173 KGV++ HR++I+ + Q N F EDV LFH Y + SV + L GS Sbjct: 1656 KGVIVEHRNVISLLKHQ----NLPFEFNHEDVWT----LFHSYCFDFSVWEMFGALLNGS 1707 Query: 174 AMVIMRKF---DIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAA 344 +V++ K D A L++ +TV P + Q D +IR V+ G Sbjct: 1708 TLVVVSKETARDPQAFRLLLKKERVTVLNQTPTAFYGLMLEDQ-NHTDHLNIRYVIFGGE 1766 Query: 345 PMGKELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLK 524 + L ++ K P+ L YG+TE + A + K KS + G + Sbjct: 1767 ALQPGLLQSWNEKYPHTDLINMYGITETTVHVTFKKLSAADIAKNKS-NIGRPLSTLQAH 1825 Query: 525 IVDPDTGASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWL 662 ++D PGE+ I GE + +GYLN E T + + +L Sbjct: 1826 VMDAHMNLQ-PTGVPGELYIGGEGVARGYLNRDELTADRFVSNPYL 1870 Score = 38.5 bits (88), Expect = 0.018 Identities = 46/226 (20%), Positives = 93/226 (41%), Gaps = 6/226 (2%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV++ H +A + ++D+ L L + S L L +G+ ++ Sbjct: 623 KGVLVDHHG----IANTLQWRREEYSMTEQDISLHLFSYVFDGCVTS-LFTPLLSGACVL 677 Query: 183 IM---RKFDIGALVELVRAHGIT---VAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAA 344 + D+ AL + + ++ + P + +++E+ +TA D S+R+V Sbjct: 678 LTTDDEAKDVLALKRKIARYKVSHMIIVPSLYRVLLEV-----MTADDAKSLRIVTFAGE 732 Query: 345 PMGKELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLK 524 + +L + P+A L YG TE ++ + K + + G +RN + Sbjct: 733 AVTPDLLELNQIICPSAELANEYGPTEN----SVATTILRHLNKKERITIGHPIRNTKVF 788 Query: 525 IVDPDTGASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWL 662 ++ + +G GE+CI G + +GY E T+ +L Sbjct: 789 VLHGNQMQPIGA--AGELCISGAGLARGYYKQQELTQKAFSDHPFL 832
>VIBE_VIBCH (O07899) Vibriobactin-specific 2,3-dihydroxybenzoate-AMP ligase (EC| 6.3.2.-) (Dihydroxybenzoic acid-activating enzyme) Length = 543 Score = 49.7 bits (117), Expect = 8e-06 Identities = 54/221 (24%), Positives = 92/221 (41%), Gaps = 4/221 (1%) Frame = +3 Query: 18 THRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLR-AGSAMVIMRK 194 TH SV V+ F + LC+LP H + L+S G+ AG +V+ + Sbjct: 207 THNDYAYSVTASVE----ICRFDQHTRYLCVLPAAHNFPLSSPGALGVFWAGGCVVLSQD 262 Query: 195 FDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKELQDAF 374 +L+ H ITV VPP+ + + + DL+S+ V G G + +A Sbjct: 263 ASPQHAFKLIEQHKITVTALVPPLALLWMDHAEKSTYDLSSLHFVQVG----GAKFSEAA 318 Query: 375 MAKIPNAV---LGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTG 545 ++P A+ L Q +GM E G V L + E G + + L +VD + G Sbjct: 319 ARRLPKALGCQLQQVFGMAE-GLVNYTRLDDSAELIATTQGR--PISAHDQLLVVD-EQG 374 Query: 546 ASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 + + G + +G ++GY + + + G+ T Sbjct: 375 QPVASGEEGYLLTQGPYTIRGYYRADQHNQRAFNAQGFYIT 415
>FAT2_YEAST (P38137) Peroxisomal-coenzyme A synthetase (EC 6.-.-.-)| Length = 543 Score = 49.3 bits (116), Expect = 1e-05 Identities = 50/183 (27%), Positives = 80/183 (43%), Gaps = 2/183 (1%) Frame = +3 Query: 108 LLPLFHIYSLNSVLLAGLRAGSAMVIMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKS 287 ++PLFH++ L VLL+ R ++V+ F + + VP I + + Sbjct: 236 VMPLFHVHGLIGVLLSTFRTQGSVVVPDGFHPKLFWDQFVKYNCNWFSCVPTISMIMLNM 295 Query: 288 PQVTA-GDLASIRMVMSGAAPMG-KELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFA 461 P+ + IR S AP +L+ F NA + + Y MTEA + + Sbjct: 296 PKPNPFPHIRFIRSCSSALAPATFHKLEKEF-----NAPVLEAYAMTEASHQMT---SNN 347 Query: 462 KEPFKVKSGSCGTVVRNAGLKIVDPDTGASLGRNQPGEICIRGEQIMKGYLNDPESTKNT 641 P K K G+ G + + I+D D L + GE+ IRGE + GY N+P++ K Sbjct: 348 LPPGKRKPGTVGQP-QGVTVVILD-DNDNVLPPGKVGEVSIRGENVTLGYANNPKANKEN 405 Query: 642 IDK 650 K Sbjct: 406 FTK 408
>MENE_STAAW (Q8NVZ4) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 492 Score = 49.3 bits (116), Expect = 1e-05 Identities = 47/191 (24%), Positives = 84/191 (43%) Frame = +3 Query: 60 GENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMVIMRKFDIGALVELVRAHGI 239 G +L F ++ L +LP++HI L SVLL + G + I+ KF+ ++ +++ I Sbjct: 192 GCKESLGFDRDTNWLSVLPIYHISGL-SVLLRAVIEGFTVRIVDKFNAEQILTIIKNERI 250 Query: 240 TVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKELQDAFMAKIPNAVLGQGYGM 419 T VP + + + +L I ++ GA ++ A +P + +GM Sbjct: 251 THISLVPQTLNWLMQQGLHEPYNLQKI--LLGGAKLSATLIETALQYNLP---IYNSFGM 305 Query: 420 TEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGASLGRNQPGEICIRGEQI 599 TE + L E + + G N +KI +P+ + GE+ I+G + Sbjct: 306 TET---CSQFLTATPEMLHARPDTVGMPSANVDVKIKNPN------KEGHGELMIKGANV 356 Query: 600 MKGYLNDPEST 632 M GYL + T Sbjct: 357 MNGYLYPTDLT 367
>MENE_STAAS (Q6G8D6) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 492 Score = 49.3 bits (116), Expect = 1e-05 Identities = 47/191 (24%), Positives = 84/191 (43%) Frame = +3 Query: 60 GENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMVIMRKFDIGALVELVRAHGI 239 G +L F ++ L +LP++HI L SVLL + G + I+ KF+ ++ +++ I Sbjct: 192 GCKESLGFDRDTNWLSVLPIYHISGL-SVLLRAVIEGFTVRIVDKFNAEQILTIIKNERI 250 Query: 240 TVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKELQDAFMAKIPNAVLGQGYGM 419 T VP + + + +L I ++ GA ++ A +P + +GM Sbjct: 251 THISLVPQTLNWLMQQGLHEPYNLQKI--LLGGAKLSATLIETALQYNLP---IYNSFGM 305 Query: 420 TEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGASLGRNQPGEICIRGEQI 599 TE + L E + + G N +KI +P+ + GE+ I+G + Sbjct: 306 TET---CSQFLTATPEMLHARPDTVGMPSANVDVKIKNPN------KEGHGELMIKGANV 356 Query: 600 MKGYLNDPEST 632 M GYL + T Sbjct: 357 MNGYLYPTDLT 367
>LCF4_YEAST (P47912) Long-chain-fatty-acid--CoA ligase 4 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 4) (Fatty acid activator 4) Length = 694 Score = 48.5 bits (114), Expect = 2e-05 Identities = 35/126 (27%), Positives = 56/126 (44%) Frame = +3 Query: 291 QVTAGDLASIRMVMSGAAPMGKELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEP 470 + T G+L R +++G + + + Q F++ + +L GYG+TE + A EP Sbjct: 417 EATGGNL---RFILNGGSAISIDAQK-FLSNLLCPML-IGYGLTEG-----VANACVLEP 466 Query: 471 FKVKSGSCGTVVRNAGLKIVDPDTGASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDK 650 G G +V K+VD + +N GE+ +G I Y +PE T Sbjct: 467 EHFDYGIAGDLVGTITAKLVDVEDLGYFAKNNQGELLFKGAPICSEYYKNPEETAAAFTD 526 Query: 651 DGWLHT 668 DGW T Sbjct: 527 DGWFRT 532
>PKSJ_BACSU (P40806) Putative polyketide synthase pksJ (PKS)| Length = 5045 Score = 47.4 bits (111), Expect = 4e-05 Identities = 49/237 (20%), Positives = 99/237 (41%), Gaps = 15/237 (6%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAG---- 170 K VML HR++++ V + + F +ED+ +P H+ + + L + G Sbjct: 203 KAVMLNHRNIMSMVKGIIQMQG----FTREDITFNWMPFDHVGGIGMLHLRDVYLGCQEI 258 Query: 171 ---SAMVIMRKFDIGALVELVRAHGITVAP-FVPPIVVEIAKSPQVTAGDLASIRMVMSG 338 S ++M ++ RA +T AP F +V + A+ + DL+S+R +++G Sbjct: 259 NVSSETILMEPLKWLDWIDHYRA-SVTWAPNFAFGLVTDFAEEIKDKKWDLSSMRYMLNG 317 Query: 339 A----APMGKELQDAFMAK-IPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSG--SCG 497 A +G+ + + +P + +GM+E + F + G Sbjct: 318 GEAMVAKVGRRILELLEPHGLPADAIRPAWGMSETSSGVIFSHEFTRAGTSDDDHFVEIG 377 Query: 498 TVVRNAGLKIVDPDTGASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 + + ++IV+ D + + G + G + GY P+ ++ +DGW T Sbjct: 378 SPIPGFSMRIVN-DHNELVEEGEIGRFQVSGLSVTSGYYQRPDLNESVFTEDGWFET 433 Score = 31.2 bits (69), Expect = 2.9 Identities = 48/212 (22%), Positives = 82/212 (38%), Gaps = 2/212 (0%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGVM+ H++L + GE P L ED +L + + + L ++ + Sbjct: 1317 KGVMIPHKALTNFLVSM--GETPGL--TAEDKMLAVTTYCFDIAALELFLPLIKGAHCYI 1372 Query: 183 IMRKF--DIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGK 356 + D+ L +RA TV P + S S++++ G A + + Sbjct: 1373 CQTEHTKDVEKLKRDIRAIKPTVMQATPATWKMLFYSGWENE---ESVKILCGGEA-LPE 1428 Query: 357 ELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDP 536 L+ F+ A +G TE + A + + + G + N + I D Sbjct: 1429 TLKRYFLDTGSEA--WNMFGPTET----TIWSAVQRINVECSHATIGRPIANTQIYITDS 1482 Query: 537 DTGASLGRNQPGEICIRGEQIMKGYLNDPEST 632 A + PGE+CI G+ + KGY E T Sbjct: 1483 QL-APVPAGVPGELCIAGDGVAKGYYKKEELT 1513
>BACB_BACLI (O68007) Bacitracin synthetase 2 (BA2) [Includes: ATP-dependent| lysine adenylase (LysA) (Lysine activase); ATP-dependent D-ornithine adenylase (D-OrnA) (D-ornithine activase); Ornithine racemase (EC 5.1.1.12)] Length = 2607 Score = 47.4 bits (111), Expect = 4e-05 Identities = 59/227 (25%), Positives = 97/227 (42%), Gaps = 9/227 (3%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGVM THR+++ VD + + D +L ++ F + + + L +V Sbjct: 673 KGVMTTHRNVV----HYVDAFTKRIPLSEHDTVLQVVS-FSFDAFSEEVYPILACSGRLV 727 Query: 183 IMRK---FDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMG 353 I RK +I LV+ + + +T+ P ++ EI K+ +T ++ + G Sbjct: 728 ISRKVSDLNIDELVKTIGKYRVTLVSCSPLLLNEIDKNQHLTFHP--QMKFISGGDVLKF 785 Query: 354 KELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVD 533 + +++ I A + YG TEA V A + K S G + N + I D Sbjct: 786 EYVENI----IKGADVYNSYGPTEA-TVCATYYQLSSADRKKTSIPIGKPLSNYKVYIAD 840 Query: 534 PDTGASLGRNQP----GEICIRGEQIMKGYLNDPESTKN--TIDKDG 656 GR QP GE+ I GE + +GYLN TK +D+ G Sbjct: 841 -----QYGRPQPVGVPGELLIGGEGVARGYLNHETLTKAAFVVDESG 882 Score = 46.6 bits (109), Expect = 7e-05 Identities = 56/228 (24%), Positives = 98/228 (42%), Gaps = 17/228 (7%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCL-LPLFHIYSLNSVLLAG-----LR 164 KGVM+ HR++I + + +RK L + L + S++ + AG L Sbjct: 1706 KGVMVEHRNII----------HAHYTWRKHYELASFSVNLLQLASMSFDVFAGDLCRSLL 1755 Query: 165 AGSAMVIMR---KFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMS 335 G M I+ K ++ L +++ +GI + P +++ + K D +S+++++ Sbjct: 1756 NGGTMYIVPDDVKLEMNLLYDMINKYGIHMLESTPSLIIPLMKYIDHHKLDFSSMKLLIM 1815 Query: 336 GAAPMG----KELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTV 503 G+ K L + F ++ + YG+TEA ++ + G Sbjct: 1816 GSDTCTIKDYKWLVERFGQRMR---IINSYGVTEASVDSGYYEEALDRIPEIANTPIGKP 1872 Query: 504 VRNAGLKIVDPDTGASLGRNQP----GEICIRGEQIMKGYLNDPESTK 635 + N I+DP QP GE+ I GE I +GYLN PE TK Sbjct: 1873 LDNTAFYILDPSLNP-----QPVGVYGELYIGGEGIARGYLNKPELTK 1915
>TYCC_BREPA (O30409) Tyrocidine synthetase 3 (Tyrocidine synthetase III)| [Includes: ATP-dependent asparagine adenylase (AsnA) (Asparagine activase); ATP-dependent glutamine adenylase (GlnA) (Glutamine activase); ATP-dependent tyrosine adenylase (TyrA) (Ty Length = 6486 Score = 47.0 bits (110), Expect = 5e-05 Identities = 54/223 (24%), Positives = 94/223 (42%), Gaps = 12/223 (5%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV++ HRS D + + + V L + F L G +V Sbjct: 4766 KGVVIEHRSYANVAFAWKDEYHLDSF----PVRLLQMASFAFDVSTGDFARALLTGGQLV 4821 Query: 183 IMR---KFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMG 353 I K D +L E +R H IT+ P +++ + D++ +++++ GA Sbjct: 4822 ICPNGVKMDPASLYETIRRHEITIFEATPALIMPLMHYVYENELDMSQMKLLILGADSCP 4881 Query: 354 KELQDAFMAKIPNAV-LGQGYGMTEAGPVLAMCLAFAKEP--FKVKSGSC--GTVVRNAG 518 E +A+ + + YG+TEA + ++ +E ++SG+ G + N Sbjct: 4882 AEDFKTLLARFGQKMRIINSYGVTEA----CIDTSYYEETDVTAIRSGTVPIGKPLPNMT 4937 Query: 519 LKIVDPDTGASLGRNQP----GEICIRGEQIMKGYLNDPESTK 635 + +VD QP GE+CI G + +GYLN PE T+ Sbjct: 4938 MYVVDAHLNL-----QPVGVVGELCIGGAGVARGYLNRPELTE 4975 Score = 46.6 bits (109), Expect = 7e-05 Identities = 49/219 (22%), Positives = 91/219 (41%), Gaps = 9/219 (4%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGVM+ HR++ V + N +E + ++ + L G+++ Sbjct: 3731 KGVMVEHRNVTRLVM------HTNYVQVRESDRMIQTGAIGFDAMTFEIFGALLHGASLY 3784 Query: 183 IMRK---FDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMG 353 ++ K D L + +R + IT P+ +++ Q S+R ++ G + Sbjct: 3785 LVSKDVLLDAEKLGDFLRTNQITTMWLTSPLFNQLS---QDNPAMFDSLRALIVGGEALS 3841 Query: 354 KELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVD 533 + + + +P+ + GYG TE + C + E + G + N+ IVD Sbjct: 3842 PKHINRVKSALPDLEIWNGYGPTE-NTTFSTC--YLIEQHFEEQIPIGKPIANSTAYIVD 3898 Query: 534 PDTGASLGRNQP------GEICIRGEQIMKGYLNDPEST 632 G NQP GE+C+ G+ + +GY+N PE T Sbjct: 3899 -------GNNQPQPIGVPGELCVGGDGVARGYVNKPELT 3930 Score = 42.7 bits (99), Expect = 0.001 Identities = 58/220 (26%), Positives = 88/220 (40%), Gaps = 10/220 (4%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGVM+ H+ ++ + + D F D L + F + L A L G+ V Sbjct: 5816 KGVMIPHQGIVNCLQWRRDEYG----FGPSDKALQVFS-FAFDGFVASLFAPLLGGATCV 5870 Query: 183 IMRKF---DIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMG 353 + ++ D AL +L+ A +T VP + I T D +R V G + Sbjct: 5871 LPQEAAAKDPVALKKLMAATEVTHYYGVPSLFQAILDCSTTT--DFNQLRCVTLGGEKLP 5928 Query: 354 KELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVR---NAGLK 524 +L K P + YG TE V + + +++G T+ R N + Sbjct: 5929 VQLVQKTKEKHPAIEINNEYGPTENSVVTTISRS-------IEAGQAITIGRPLANVQVY 5981 Query: 525 IVDPDTGASLGRNQP----GEICIRGEQIMKGYLNDPEST 632 IVD QP GE+CI G + +GYLN PE T Sbjct: 5982 IVDEQHHL-----QPIGVVGELCIGGAGLARGYLNKPELT 6016 Score = 40.8 bits (94), Expect = 0.004 Identities = 55/218 (25%), Positives = 92/218 (42%), Gaps = 7/218 (3%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGVM+ HR ++ +V + + R LL L F + L+ + +G+ +V Sbjct: 2695 KGVMVEHRGIVNNVLWKKAEYQMKVGDRS---LLSLSFAFDAFVLS--FFTPVLSGATVV 2749 Query: 183 IMRKF---DIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMG 353 + D +L +L+ A T+ VP + I + T D+ ++ V G + Sbjct: 2750 LAEDEEAKDPVSLKKLIAASRCTLMTGVPSLFQAILECS--TPADIRPLQTVTLGGEKIT 2807 Query: 354 KELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVD 533 +L + P+ V+ YG TE+ V+A A + + G + N L IV+ Sbjct: 2808 AQLVEKCKQLNPDLVIVNEYGPTESS-VVATWQRLAGPDAAI---TIGRPIANTSLYIVN 2863 Query: 534 PDTGASLGRNQP----GEICIRGEQIMKGYLNDPESTK 635 + QP GEICI G + +GY N P T+ Sbjct: 2864 -----QYHQLQPIGVVGEICIGGRGLARGYWNKPALTE 2896 Score = 37.7 bits (86), Expect = 0.031 Identities = 50/223 (22%), Positives = 93/223 (41%), Gaps = 12/223 (5%) Frame = +3 Query: 3 KGVMLTHRSLITSV--AQQVDGENPNLYFRKEDVLLCLLPLFHIYSLN---SVLLAGLRA 167 KG M+TH+ L+ + A +V + + F PL+ S + + + L + Sbjct: 620 KGAMITHQGLVNYIWWANKVYVQGEAVDF----------PLYSSISFDLTVTSIFTPLLS 669 Query: 168 GSAMVIMRKFD-IGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGA- 341 G+ + + R D + ++++++ + + + P + K + G +SIR + G Sbjct: 670 GNTIHVYRGADKVQVILDIIKDNKVGIIKLTPTHL----KLIEHIDGKASSIRRFIVGGE 725 Query: 342 ---APMGKELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSC--GTVV 506 + K++ D F N + YG TE + C+ + +P S G Sbjct: 726 NLPTKLAKQIYDHFGE---NVQIFNEYGPTET---VVGCMIYLYDPQTTTQESVPIGVPA 779 Query: 507 RNAGLKIVDPDTGASLGRNQPGEICIRGEQIMKGYLNDPESTK 635 N L ++D + GE+ I G+ + KGY N PE TK Sbjct: 780 DNVQLYLLDASM-QPVPVGSLGEMYIAGDGVAKGYFNRPELTK 821 Score = 32.7 bits (73), Expect = 1.0 Identities = 51/218 (23%), Positives = 84/218 (38%), Gaps = 7/218 (3%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGVM++H+++ + + ED +L P S+ L L G +V Sbjct: 1656 KGVMISHQAICNHMLWMRE----TFPLTTEDAVLQKTPFSFDASVWEFYLP-LITGGQLV 1710 Query: 183 IMRKF---DIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMG 353 + + DI + L+R IT VP ++ + P +A S++ V G + Sbjct: 1711 LAKPDGHRDIAYMTRLIRDEKITTLQMVPSLLDLVMTDPGWSA--CTSLQRVFCGGEALT 1768 Query: 354 KELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVD 533 L F + A L YG TE ++ + G + N L +V+ Sbjct: 1769 PALVSRFY-ETQQAQLINLYGPTETTIDATYWPCPRQQEYSAIP--IGKPIDNVRLYVVN 1825 Query: 534 PDTGASLGRNQP----GEICIRGEQIMKGYLNDPESTK 635 + QP GE+CI G+ + +GY E TK Sbjct: 1826 ASN-----QLQPVGVAGELCIAGDGLARGYWQREELTK 1858
>MENE_STAAU (Q53634) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 492 Score = 46.2 bits (108), Expect = 9e-05 Identities = 46/191 (24%), Positives = 83/191 (43%) Frame = +3 Query: 60 GENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMVIMRKFDIGALVELVRAHGI 239 G +L F ++ L +LP++HI L SVLL + G + I+ KF+ ++ +++ I Sbjct: 192 GCKESLGFDRDTNWLSVLPIYHISGL-SVLLRAVIEGFTVRIVDKFNAEQILTMIKNERI 250 Query: 240 TVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKELQDAFMAKIPNAVLGQGYGM 419 T VP + + + +L I ++ GA ++ A +P + +GM Sbjct: 251 THISLVPQTLNWLMQQGLHEPYNLQKI--LLGGAKLSATMIETALQYNLP---IYNSFGM 305 Query: 420 TEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGASLGRNQPGEICIRGEQI 599 TE + L E + + G N +KI +P+ + GE+ I+G + Sbjct: 306 TE---TCSQFLTATPEMLHARPDTVGMPSANVDVKIKNPN------KEGHGELMIKGANV 356 Query: 600 MKGYLNDPEST 632 M YL + T Sbjct: 357 MNVYLYPTDLT 367
>MENE_STAAC (Q5HEY2) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 492 Score = 46.2 bits (108), Expect = 9e-05 Identities = 46/191 (24%), Positives = 83/191 (43%) Frame = +3 Query: 60 GENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMVIMRKFDIGALVELVRAHGI 239 G +L F ++ L +LP++HI L SVLL + G + I+ KF+ ++ +++ I Sbjct: 192 GCKESLGFDRDTNWLSVLPIYHISGL-SVLLRAVIEGFTVRIVDKFNAEQILTMIKNERI 250 Query: 240 TVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKELQDAFMAKIPNAVLGQGYGM 419 T VP + + + +L I ++ GA ++ A +P + +GM Sbjct: 251 THISLVPQTLNWLMQQGLHEPYNLQKI--LLGGAKLSATMIETALQYNLP---IYNSFGM 305 Query: 420 TEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGASLGRNQPGEICIRGEQI 599 TE + L E + + G N +KI +P+ + GE+ I+G + Sbjct: 306 TE---TCSQFLTATPEMLHARPDTVGMPSANVDVKIKNPN------KEGHGELMIKGANV 356 Query: 600 MKGYLNDPEST 632 M YL + T Sbjct: 357 MNVYLYPTDLT 367
>LGRA_BREPA (Q70LM7) Linear gramicidin synthetase subunit A [Includes:| ATP-dependent valine/leucine adenylase (Val/LeuA) (Valine/leucine activase); ATP-dependent glycine adenylase (GlyA) (Glycine activase)] Length = 2273 Score = 46.2 bits (108), Expect = 9e-05 Identities = 54/215 (25%), Positives = 96/215 (44%), Gaps = 4/215 (1%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGVM+ H +L+ +V + E P L ++D L L +I+ ++ + G G + Sbjct: 1376 KGVMIEHGALL-NVLHGMQDEYPLL---QDDAFL--LKTTYIFDISVAEIFGWVPGRGKL 1429 Query: 183 IMRKFDIG----ALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPM 350 ++ + + A+ + V GIT FVP +++ + + + +R +++ M Sbjct: 1430 VILEPEAEKNPKAIWQAVVGAGITHINFVPSMLIPFVEYLEGRT-EANRLRYILACGEAM 1488 Query: 351 GKELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIV 530 EL +P L YG TEA + A + AK + G + N + I+ Sbjct: 1489 PDELVPKVYEVLPEVKLENIYGPTEA-TIYASRYSLAKGS-QESPVPIGKPLPNYRMYII 1546 Query: 531 DPDTGASLGRNQPGEICIRGEQIMKGYLNDPESTK 635 + G PGE+CI G + +GYLN+P T+ Sbjct: 1547 NRH-GQLQPIGVPGELCIAGASLARGYLNNPALTE 1580 Score = 38.9 bits (89), Expect = 0.014 Identities = 59/219 (26%), Positives = 95/219 (43%), Gaps = 9/219 (4%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLL---AGLRAGS 173 KGVM+ H +L+ + P D L ++ +S + L L AG+ Sbjct: 358 KGVMIEHHNLVNFC----EWYRPYFGVTPADKAL----VYSSFSFDGSALDIFTHLLAGA 409 Query: 174 AMVIM---RKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAA 344 A+ I+ RK+D+ AL + GIT++ ++P E Q D S R+V++G Sbjct: 410 ALHIVPSERKYDLDALNDYCNQEGITIS-YLPTGAAE-----QFMQMDNQSFRVVITGGD 463 Query: 345 PMGKELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLA---FAKEPFKVKSGSCGTVVRNA 515 + K+++ K+ N GYG TE ++ M +A P G + Sbjct: 464 VL-KKIERNGTYKLYN-----GYGPTECTIMVTMFEVDKPYANIPI-------GKPIDRT 510 Query: 516 GLKIVDPDTGASLGRNQPGEICIRGEQIMKGYLNDPEST 632 + I+D + A GE+ I GE + +GYLN PE T Sbjct: 511 RILILD-EALALQPIGVAGELFIVGEGLGRGYLNRPELT 548
>S27A5_HUMAN (Q9Y2P5) Bile acyl-CoA synthetase (EC 6.2.1.7) (BACS) (Bile acid| CoA ligase) (BA-CoA ligase) (BAL) (Cholate--CoA ligase) (Very long-chain acyl-CoA synthetase homolog 2) (VLCSH2) (VLCS-H2) (Very long chain acyl-CoA synthetase-related protein) Length = 690 Score = 46.2 bits (108), Expect = 9e-05 Identities = 28/112 (25%), Positives = 52/112 (46%) Frame = +3 Query: 90 EDVLLCLLPLFHIYSLNSVLLAGLRAGSAMVIMRKFDIGALVELVRAHGITVAPFVPPIV 269 +DV+ +LPL+H+ L +L L G+ V+ KF + R HG+TV +V ++ Sbjct: 327 DDVVYTVLPLYHVMGLVVGILGCLDLGATCVLAPKFSTSCFWDDCRQHGVTVILYVGELL 386 Query: 270 VEIAKSPQVTAGDLASIRMVMSGAAPMGKELQDAFMAKIPNAVLGQGYGMTE 425 + PQ ++R+ M + ++ + F + + + YG TE Sbjct: 387 RYLCNIPQQPEDRTHTVRLAMGNG--LRADVWETFQQRFGPIRIWEVYGSTE 436
>ENTE_ECO57 (Q8XBV3) Enterobactin synthetase component E (Enterochelin synthase| E) [Includes: 2,3-dihydroxybenzoate-AMP ligase (EC 2.7.7.58) (Dihydroxybenzoic acid-activating enzyme); S-dihydroxybenzoyltransferase (EC 2.3.1.-)] Length = 536 Score = 46.2 bits (108), Expect = 9e-05 Identities = 52/226 (23%), Positives = 87/226 (38%), Gaps = 12/226 (5%) Frame = +3 Query: 18 THRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGL-RAGSAMVIMRK 194 TH SV + V+ F ++ LC +P H Y+++S G+ AG +V+ Sbjct: 203 THNDYYYSVRRSVE----ICQFTQQTRYLCAIPAAHNYAMSSPGSLGVFLAGGTVVLAAD 258 Query: 195 FDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGD----LASIRMVMSGAAPMGKEL 362 L+ H I V VPP V ++ +T G+ LAS++++ G A + L Sbjct: 259 PSATLCFPLIEKHQINVTALVPPAVSLWLQA--LTEGESRAQLASLKLLQVGGARLSATL 316 Query: 363 QDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPD- 539 A+I L Q +GM E + S ++ G + D Sbjct: 317 AARIPAEI-GCQLQQVFGMAE-----------GLVNYTRLDDSAEKIIHTQGYPMCPDDE 364 Query: 540 ------TGASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGW 659 G L + + G + RG +GY P+ + D +G+ Sbjct: 365 VWVADAEGNPLPQGEVGRLMTRGPYTFRGYYKSPQHNASAFDANGF 410
>ACVS2_PENCH (P26046) N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase| (EC 6.3.2.26) (Delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase) (ACV synthetase) (ACVS) Length = 3791 Score = 45.4 bits (106), Expect = 2e-04 Identities = 60/220 (27%), Positives = 94/220 (42%), Gaps = 10/220 (4%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQ-----VDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRA 167 KG+ H +++ S+ V G++ E +LL +F + + L+A + Sbjct: 491 KGIFKQHTNVVNSITDLSARYGVAGQH------HEAILLFSACVFEPF-VRQTLMALVNG 543 Query: 168 GSAMVI--MRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGA 341 VI + K+D L+ +R H IT ++ E S D S+ ++ Sbjct: 544 HLLAVINDVEKYDADTLLPFIRRHSITYLNGTASVLQEYDFS------DCPSLNRIILVG 597 Query: 342 APMGKELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGL 521 + + A + N +L + YG TE+ V A+ + F E + K S G VRN Sbjct: 598 ENLTEARYLALRQRFKNRILNE-YGFTESAFVTALKI-FDPESTR-KDTSLGRPVRNVKC 654 Query: 522 KIVDPDTGASLGR---NQPGEICIRGEQIMKGYLNDPEST 632 I++P SL R GE+ I G I KGYLN PE T Sbjct: 655 YILNP----SLKRVPIGATGELHIGGLGISKGYLNRPELT 690
>LCFH_HAEIN (P44446) Putative long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase) (LACS) Length = 607 Score = 45.4 bits (106), Expect = 2e-04 Identities = 39/117 (33%), Positives = 52/117 (44%) Frame = +3 Query: 318 IRMVMSGAAPMGKELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCG 497 I+M+ G A + + F A N LG YGMTE ++ F P S G Sbjct: 351 IKMMPCGGAKLEPAIGLFFHAIGINIKLG--YGMTETTATVSCWHDFQFNP-----NSIG 403 Query: 498 TVVRNAGLKIVDPDTGASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 T++ A +KI G N EI +RG +MKGY PE T +DG+L T Sbjct: 404 TLMPKAEVKI---------GENN--EILVRGGMVMKGYYKKPEETAQAFTEDGFLKT 449
>ACVS1_PENCH (P19787) N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase| (EC 6.3.2.26) (Delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase) (ACV synthetase) (ACVS) Length = 3746 Score = 45.4 bits (106), Expect = 2e-04 Identities = 60/220 (27%), Positives = 94/220 (42%), Gaps = 10/220 (4%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQ-----VDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRA 167 KG+ H +++ S+ V G++ E +LL +F + + L+A + Sbjct: 461 KGIFKQHTNVVNSITDLSARYGVAGQH------HEAILLFSACVFEPF-VRQTLMALVNG 513 Query: 168 GSAMVI--MRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGA 341 VI + K+D L+ +R H IT ++ E S D S+ ++ Sbjct: 514 HLLAVINDVEKYDADTLLPFIRRHSITYLNGTASVLQEYDFS------DCPSLNRIILVG 567 Query: 342 APMGKELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGL 521 + + A + N +L + YG TE+ V A+ + F E + K S G VRN Sbjct: 568 ENLTEARYLALRQRFKNRILNE-YGFTESAFVTALKI-FDPESTR-KDTSLGRPVRNVKC 624 Query: 522 KIVDPDTGASLGR---NQPGEICIRGEQIMKGYLNDPEST 632 I++P SL R GE+ I G I KGYLN PE T Sbjct: 625 YILNP----SLKRVPIGATGELHIGGLGISKGYLNRPELT 660
>FAD21_MYCTU (P63523) Putative fatty-acid--CoA ligase fadD21 (EC 6.2.1.-)| (Acyl-CoA synthetase) Length = 578 Score = 45.1 bits (105), Expect = 2e-04 Identities = 58/247 (23%), Positives = 99/247 (40%), Gaps = 35/247 (14%) Frame = +3 Query: 6 GVMLTHRSLITSVAQQVDGE--NPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAM 179 GVM++HR+L + Q + + N + ++ LP +H L ++A + G Sbjct: 179 GVMISHRNLQANFQQLMSNYFGDRNGVAPPDTTIVSWLPFYHDMGLVLGIIAPILGGYRS 238 Query: 180 VIMRKFDIGALVELVR-----AHGITVAPFVPPIVVEIAKSPQVTAG----DLASIRMVM 332 + + L R A+G P E+A A DL ++ + Sbjct: 239 ELTSP--LAFLQRPARWLHSLANGSPSWSAAPNFAFELAVRKTTDADIEGLDLGNVLGIT 296 Query: 333 SGAAPMGKELQDAFMAKIP-----NAVLGQGYGMTEAGPVLAMCLAFAK------EPFKV 479 SGA + F + ++ YG+ EA +A + K EP K+ Sbjct: 297 SGAERVHPNTLSRFCNRFAPYNFREDMIRPSYGLAEATLYVASRNSGDKPEVVYFEPDKL 356 Query: 480 KSGSC-------GTVVRNAGL------KIVDPDTGASLGRNQPGEICIRGEQIMKGYLND 620 +GS GT + + G+ +IVDPDT GEI ++G+ + +GY N Sbjct: 357 STGSANRCEPKTGTPLLSYGMPTSPTVRIVDPDTCIECPAGTIGEIWVKGDNVAEGYWNK 416 Query: 621 PESTKNT 641 P+ T++T Sbjct: 417 PDETRHT 423
>FAD21_MYCBO (P63524) Putative fatty-acid--CoA ligase fadD21 (EC 6.2.1.-)| (Acyl-CoA synthetase) Length = 578 Score = 45.1 bits (105), Expect = 2e-04 Identities = 58/247 (23%), Positives = 99/247 (40%), Gaps = 35/247 (14%) Frame = +3 Query: 6 GVMLTHRSLITSVAQQVDGE--NPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAM 179 GVM++HR+L + Q + + N + ++ LP +H L ++A + G Sbjct: 179 GVMISHRNLQANFQQLMSNYFGDRNGVAPPDTTIVSWLPFYHDMGLVLGIIAPILGGYRS 238 Query: 180 VIMRKFDIGALVELVR-----AHGITVAPFVPPIVVEIAKSPQVTAG----DLASIRMVM 332 + + L R A+G P E+A A DL ++ + Sbjct: 239 ELTSP--LAFLQRPARWLHSLANGSPSWSAAPNFAFELAVRKTTDADIEGLDLGNVLGIT 296 Query: 333 SGAAPMGKELQDAFMAKIP-----NAVLGQGYGMTEAGPVLAMCLAFAK------EPFKV 479 SGA + F + ++ YG+ EA +A + K EP K+ Sbjct: 297 SGAERVHPNTLSRFCNRFAPYNFREDMIRPSYGLAEATLYVASRNSGDKPEVVYFEPDKL 356 Query: 480 KSGSC-------GTVVRNAGL------KIVDPDTGASLGRNQPGEICIRGEQIMKGYLND 620 +GS GT + + G+ +IVDPDT GEI ++G+ + +GY N Sbjct: 357 STGSANRCEPKTGTPLLSYGMPTSPTVRIVDPDTCIECPAGTIGEIWVKGDNVAEGYWNK 416 Query: 621 PESTKNT 641 P+ T++T Sbjct: 417 PDETRHT 423
>LGRB_BREPA (Q70LM6) Linear gramicidin synthetase subunit B [Includes:| ATP-dependent alanine adenylase (AlaA) (Alanine activase); ATP-dependent D-leucine adenylase (D-LeuA) (D-leucine activase); Leucine racemase [ATP-hydrolyzing] (EC 5.1.1.-); ATP-depende Length = 5162 Score = 44.7 bits (104), Expect = 3e-04 Identities = 54/216 (25%), Positives = 91/216 (42%), Gaps = 6/216 (2%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGVM+ H SL+ + + LY E+ LL + + ++ + G GS + Sbjct: 615 KGVMIEHASLLNIIFALQE-----LYPLLENDAY-LLKTTYTFDVSVAEIFGWILGSGRL 668 Query: 183 IMRKFDIGA------LVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAA 344 ++ D GA + E + HG+T FVP +++ + + + +R + + Sbjct: 669 VI--LDPGAEKEPAHIWETMVNHGVTHVNFVPSMLIPFVDYVRDQQQE-SPLRYIFAAGE 725 Query: 345 PMGKELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLK 524 M EL +P +L YG TE+ + A + AK+ V G + N Sbjct: 726 AMPSELVGKVYEALPGVILENIYGPTES-TIYATKYSLAKDSQDVLV-PIGKPLANIQTH 783 Query: 525 IVDPDTGASLGRNQPGEICIRGEQIMKGYLNDPEST 632 IV+ G PGE+CI G + +GY N+ T Sbjct: 784 IVNKH-GQLQPVGVPGELCIAGASLARGYWNNEALT 818 Score = 33.1 bits (74), Expect = 0.78 Identities = 33/134 (24%), Positives = 61/134 (45%) Frame = +3 Query: 234 GITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKELQDAFMAKIPNAVLGQGY 413 GIT++ P+ + P T A++R +++G G L A +P ++ Q Y Sbjct: 1754 GITISFLPTPLAENLLPLPWPTG---AALRYMLTG----GDTLHQYPTADVPFTLVNQ-Y 1805 Query: 414 GMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGASLGRNQPGEICIRGE 593 G TE V+A A + + + G + N + ++D + + GE+ I G+ Sbjct: 1806 GPTE-NTVVATAGAVPVLGERESAPTIGRPIDNVSVYVLD-ENRQPVPVGVVGELYIGGK 1863 Query: 594 QIMKGYLNDPESTK 635 + +GY N P+ T+ Sbjct: 1864 SLARGYRNRPDLTE 1877
>ENTE_ECOLI (P10378) Enterobactin synthetase component E (Enterochelin synthase| E) [Includes: 2,3-dihydroxybenzoate-AMP ligase (EC 2.7.7.58) (Dihydroxybenzoic acid-activating enzyme); S-dihydroxybenzoyltransferase (EC 2.3.1.-)] Length = 536 Score = 44.7 bits (104), Expect = 3e-04 Identities = 49/224 (21%), Positives = 84/224 (37%), Gaps = 10/224 (4%) Frame = +3 Query: 18 THRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGL-RAGSAMVIMRK 194 TH SV + V+ F ++ LC +P H Y+++S G+ AG +V+ Sbjct: 203 THNDYYYSVRRSVE----ICQFTQQTRYLCAIPAAHNYAMSSPGSLGVFLAGGTVVLAAD 258 Query: 195 FDIGALVELVRAHGITVAPFVPPIVVEIAKS--PQVTAGDLASIRMVMSGAAPMGKELQD 368 L+ H + V VPP V ++ + LAS++++ G A + L Sbjct: 259 PSATLCFPLIEKHQVNVTALVPPAVSLWLQALIEGESRAQLASLKLLQVGGARLSATLAA 318 Query: 369 AFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPD--- 539 A+I L Q +GM E + S ++ G + D Sbjct: 319 RIPAEI-GCQLQQVFGMAE-----------GLVNYTRLDDSAEKIIHTQGYPMCPDDEVW 366 Query: 540 ----TGASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGW 659 G L + + G + RG +GY P+ + D +G+ Sbjct: 367 VADAEGNPLPQGEVGRLMTRGPYTFRGYYKSPQHNASAFDANGF 410
>DHBE_BACSU (P40871) 2,3-dihydroxybenzoate-AMP ligase (EC 6.3.2.-)| (Dihydroxybenzoic acid-activating enzyme) Length = 539 Score = 44.7 bits (104), Expect = 3e-04 Identities = 48/218 (22%), Positives = 84/218 (38%), Gaps = 1/218 (0%) Frame = +3 Query: 18 THRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAG-LRAGSAMVIMRK 194 TH I S+ + V+ + V L LP+ H Y L+S + G L AG +V+ Sbjct: 203 THDDYIYSLKRSVEV----CWLDHSTVYLAALPMAHNYPLSSPGVLGVLYAGGRVVLSPS 258 Query: 195 FDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKELQDAF 374 L+ +T+ VPP+ + + DL+S++++ G A E Sbjct: 259 PSPDDAFPLIEREKVTITALVPPLAMVWMDAASSRRDDLSSLQVLQVGGAKFSAEAARRV 318 Query: 375 MAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGASL 554 A + L Q +GM E + +P ++ + G + V D + Sbjct: 319 KA-VFGCTLQQVFGMAEG----LVNYTRLDDPEEIIVNTQGKPMSPYDEMRVWDDHDRDV 373 Query: 555 GRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 + G + RG ++GY E + +DG+ T Sbjct: 374 KPGETGHLLTRGPYTIRGYYKAEEHNAASFTEDGFYRT 411
>LCF1_SCHPO (O60135) Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 1) (Fatty acid activator 1) Length = 676 Score = 44.7 bits (104), Expect = 3e-04 Identities = 28/89 (31%), Positives = 43/89 (48%), Gaps = 2/89 (2%) Frame = +3 Query: 408 GYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGASLGRNQP--GEIC 581 GYG+TE + A + F + S G+++ +K+VD + G P GEI Sbjct: 432 GYGLTE---ISAAAMVQNPACFNLDD-SAGSLLPCTEMKLVDCEEGNYNSHGHPPRGEIW 487 Query: 582 IRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 +RG + +GYLN + K + DGW T Sbjct: 488 LRGPSLTRGYLNRDKENKESFTPDGWFRT 516
>ACSL4_RAT (O35547) Long-chain-fatty-acid--CoA ligase 4 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 4) (LACS 4) Length = 670 Score = 44.3 bits (103), Expect = 3e-04 Identities = 37/122 (30%), Positives = 57/122 (46%), Gaps = 8/122 (6%) Frame = +3 Query: 315 SIRMVMSGAAPMGKELQDAFMAKIPNAVLGQGYGMTE---AGPVLAMCLAFAKEPFKVKS 485 ++RM++SG AP+ + FM +GQGYG+TE AG V E + Sbjct: 394 NVRMMLSGGAPLSPQTH-RFMNVCFCCPIGQGYGLTESCGAGTVT--------EVTDYTT 444 Query: 486 GSCGTVVRNAGLKIVDPDTGASLGRNQP---GEICIRGEQIMKGYLNDPESTKN--TIDK 650 G G + +K+ D G ++P GEI I G+ I GY + E T ++D+ Sbjct: 445 GRVGAPLICCEIKLKDWQEGGYTVHDKPNPRGEIVIGGQNISMGYFKNEEKTAEDYSVDE 504 Query: 651 DG 656 +G Sbjct: 505 NG 506
>S27A5_MOUSE (Q4LDG0) Bile acyl-CoA synthetase (EC 6.2.1.7) (BACS) (Bile acid| CoA ligase) (BA-CoA ligase) (BAL) (Cholate--CoA ligase) (Very long chain acyl-CoA synthetase-related protein) (VLACS-related) (VLACSR) (Fatty acid transport protein 5) (FATP-5) Length = 689 Score = 43.9 bits (102), Expect = 4e-04 Identities = 28/99 (28%), Positives = 45/99 (45%), Gaps = 2/99 (2%) Frame = +3 Query: 84 RKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMVIMRKFDIGALVELVRAHGITVAPFVPP 263 R +DV+ +LPL+H L L L+ G+ V+ KF R HG+TV +V Sbjct: 324 RADDVVYDVLPLYHTIGLVLGFLGCLQVGATCVLAPKFSASRFWAECRQHGVTVILYVGE 383 Query: 264 IVVEIAKSPQVTAGDLASIRMVMSGA--APMGKELQDAF 374 I+ + P+ + ++R+ M A + K Q F Sbjct: 384 ILRYLCNVPEQPEDKIHTVRLAMGNGLRANVWKNFQQRF 422
>ACSL4_HUMAN (O60488) Long-chain-fatty-acid--CoA ligase 4 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 4) (LACS 4) Length = 711 Score = 43.9 bits (102), Expect = 4e-04 Identities = 37/122 (30%), Positives = 57/122 (46%), Gaps = 8/122 (6%) Frame = +3 Query: 315 SIRMVMSGAAPMGKELQDAFMAKIPNAVLGQGYGMTE---AGPVLAMCLAFAKEPFKVKS 485 ++RM++SG AP+ + FM +GQGYG+TE AG V E + Sbjct: 435 NVRMMLSGGAPLSPQTH-RFMNVCFCCPIGQGYGLTESCGAGTVT--------EVTDYTT 485 Query: 486 GSCGTVVRNAGLKIVDPDTGASLGRNQP---GEICIRGEQIMKGYLNDPESTKN--TIDK 650 G G + +K+ D G ++P GEI I G+ I GY + E T ++D+ Sbjct: 486 GRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVIGGQNISMGYFKNEEKTAEDYSVDE 545 Query: 651 DG 656 +G Sbjct: 546 NG 547
>BACA_BACLI (O68006) Bacitracin synthetase 1 (BA1) [Includes: ATP-dependent| isoleucine adenylase (IleA) (Isoleucine activase); ATP-dependent cysteine adenylase (CysA) (Cysteine activase); ATP-dependent leucine adenylase (LeuA) (Leucine activase); ATP-depe Length = 5255 Score = 43.5 bits (101), Expect = 6e-04 Identities = 55/217 (25%), Positives = 91/217 (41%), Gaps = 7/217 (3%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLN-SVLLAGLRAGSAM 179 KGVM+ H S V V G N +Y + L L +I+ + + A L G + Sbjct: 3304 KGVMIEHHS----VNNLVHGLNERIYQHLDAHLNVALVAPYIFDASVKQIFAALLFGHTL 3359 Query: 180 VIMRK---FDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLA-SIRMVMSGAAP 347 I+ + +D +L+E + I V+ P + +A V +L ++ ++ G Sbjct: 3360 CIVPRETAWDAMSLIEYYSKNNINVSDMTPAHLNMLA---YVDKTELEFDVKELIVGGDA 3416 Query: 348 MGKELQDAFMAKIPNAV--LGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGL 521 + ++ K PN + YG TE A + + + S G + N + Sbjct: 3417 LTPDVIGGLFHKFPNLSCNITNVYGPTECCVDAASHQIESGKVPQTPSIPIGRPLLNTSI 3476 Query: 522 KIVDPDTGASLGRNQPGEICIRGEQIMKGYLNDPEST 632 IVD + L GE+CI GE + +GY+N PE T Sbjct: 3477 YIVDKEL-RPLPVGIAGELCIAGEGVARGYVNRPELT 3512 Score = 42.4 bits (98), Expect = 0.001 Identities = 56/222 (25%), Positives = 95/222 (42%), Gaps = 11/222 (4%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVD----GENPNLYFRKEDVLLCLLPLFHIYSLNSV---LLAGL 161 KGVM+ H+SLI + G+N N ++ S ++ L + Sbjct: 2282 KGVMIEHQSLINLCSWHQSCFEVGQNDNS------------SIYASISFDAFVWELFPYI 2329 Query: 162 RAGSAMVIMR---KFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVM 332 AG+ + ++ + D+ L H IT++ F+P V E Q TA D S+R ++ Sbjct: 2330 TAGATVHVLNQETRLDVEKLNRYFHDHHITIS-FLPTPVCE-----QFTALDNHSLRTLL 2383 Query: 333 SGAAPMGKELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRN 512 +G + + ++ + YG TE V+A K + G + N Sbjct: 2384 TGGDKLNVFKEKSYQ-------IVNNYGPTE-NTVVATSFPIDKSHQNIPIGK---PIDN 2432 Query: 513 AGLKIVDPDTG-ASLGRNQPGEICIRGEQIMKGYLNDPESTK 635 + I++ D LG + GE+CI GE + +GY+N PE T+ Sbjct: 2433 VKVYILNKDLQLCPLGAS--GELCIAGEGLARGYVNRPELTR 2472 Score = 41.6 bits (96), Expect = 0.002 Identities = 51/212 (24%), Positives = 89/212 (41%), Gaps = 2/212 (0%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV++ H S A +V + DV+L L S+ + A L S ++ Sbjct: 4820 KGVVIPHYS-----AARVVKNTNYIDITGNDVILQLSNYSFDGSVFDIFGALLNGASLVL 4874 Query: 183 IMRKFDIGA--LVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGK 356 I ++ + L E+++ ++V + +A + G LA +R ++ G Sbjct: 4875 IEKETVLNTHELAEVIKKEQVSVMFITTALFNTLA---DINIGCLAKLRKILFGGERASI 4931 Query: 357 ELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDP 536 + + L YG TE+ V A + + ++ G+ + N + I+D Sbjct: 4932 PHVRKVLDHVGRDKLIHVYGPTES-TVYATYYFINEIDDEAETIPIGSPLANTSVLIMD- 4989 Query: 537 DTGASLGRNQPGEICIRGEQIMKGYLNDPEST 632 + G L PGE+CI G+ + KGYLN E T Sbjct: 4990 EAGKLLPIGVPGELCIAGDGLSKGYLNREELT 5021 Score = 41.6 bits (96), Expect = 0.002 Identities = 53/217 (24%), Positives = 93/217 (42%), Gaps = 7/217 (3%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV+ H S+I V +N N ED ++ L + + L G+++V Sbjct: 193 KGVITPHYSVIRVV------QNTNYIDITEDNVILQLSNYSFDGSVFDIFGALLNGASLV 246 Query: 183 IMRK---FDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMG 353 ++ K +I L + ++V + IA + L+++R ++ G G Sbjct: 247 MIEKEALLNINRLGSAINEEKVSVMFITTALFNMIA---DIHVDCLSNLRKILFG----G 299 Query: 354 KELQDAFMAKIPNAV----LGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGL 521 + + K+ N V L YG TE+ V A + + ++ G+ + N + Sbjct: 300 ERASIPHVRKVLNHVGRDKLIHVYGPTES-TVYATYYFINEIDDEAETIPIGSPLANTSV 358 Query: 522 KIVDPDTGASLGRNQPGEICIRGEQIMKGYLNDPEST 632 I+D + G + PGE+CI G+ + KGYLN E T Sbjct: 359 LIMD-EAGKLVPIGVPGELCIAGDGLSKGYLNREELT 394
>HTS1_COCCA (Q01886) HC-toxin synthetase (EC 6.3.2.-) (HTS)| Length = 5218 Score = 43.1 bits (100), Expect = 7e-04 Identities = 56/224 (25%), Positives = 88/224 (39%), Gaps = 5/224 (2%) Frame = +3 Query: 3 KGVMLTHR--SLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSA 176 KGV++ HR SL + + G N + L+ L + I++ VL AG G Sbjct: 3142 KGVVMEHRAWSLGFTCHAEYMGFNSCTRILQFSSLMFDLSILEIWA---VLYAG---GCL 3195 Query: 177 MVIMRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGK 356 + K + L + R + I P I + DL +I PM + Sbjct: 3196 FIPSDKERVNNLQDFTRINDINTVFLTPSI------GKLLNPKDLPNISFAGFIGEPMTR 3249 Query: 357 ELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDP 536 L DA+ +P L YG TEA ++ P S + G + A + +V+P Sbjct: 3250 SLIDAWT--LPGRRLVNSYGPTEACVLVTAREISPTAPHDKPSSNIGHAL-GANIWVVEP 3306 Query: 537 DTGASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDK---DGW 659 A + GE+CI + + YL +PE T+ + D W Sbjct: 3307 QRTALVPIGAVGELCIEAPSLARCYLANPERTEYSFPSTVLDNW 3350 Score = 38.9 bits (89), Expect = 0.014 Identities = 48/175 (27%), Positives = 65/175 (37%), Gaps = 6/175 (3%) Frame = +3 Query: 159 LRAGSAMVIMRKFDIG--ALVELVRAHGITVAPFVPPIVVEIAKS--PQVTAGDLASIRM 326 L G + I R+ D + + +G+T A P + + + P + A +A + Sbjct: 2039 LAVGGCLCIPREEDRNPAGITTFINRYGVTWAGITPSLALHLDPDAVPTLKALCVAGEPL 2098 Query: 327 VMSGAAPMGKELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVV 506 MS K L M YG TEA C+A G Sbjct: 2099 SMSVVTVWSKRLNLINM-----------YGPTEA---TVACIANQVTCTTTTVSDIGRGY 2144 Query: 507 RNAGLKIVDPDTGASLGR-NQPGEICIRGEQIMKGYLNDPESTKNT-IDKDGWLH 665 R A +V PD SL GE+ I G + +GYLNDPE T I WLH Sbjct: 2145 R-ATTWVVQPDNHNSLVPIGAVGELIIEGSILCRGYLNDPERTAEVFIRSPSWLH 2198
>DLTA_STRMU (Q53526) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 516 Score = 43.1 bits (100), Expect = 7e-04 Identities = 28/84 (33%), Positives = 39/84 (46%) Frame = +3 Query: 381 KIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGASLGR 560 + P A + YG TEA L+ K K G ++ I+D ++G L Sbjct: 290 RFPQARIVNAYGPTEATVALSALAVTDKMLETCKRLPIGYTKPDSPTFIID-ESGHKLAN 348 Query: 561 NQPGEICIRGEQIMKGYLNDPEST 632 Q GEI + G + KGYLN+PE T Sbjct: 349 GQQGEIIVSGPAVSKGYLNNPERT 372
>ACVS_CEPAC (P25464) N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase| (EC 6.3.2.26) (Delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase) (ACV synthetase) (ACVS) Length = 3712 Score = 42.7 bits (99), Expect = 0.001 Identities = 58/226 (25%), Positives = 94/226 (41%), Gaps = 15/226 (6%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQ-----VDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRA 167 KG+ H S++ S+ V GE +D ++ + + +L L Sbjct: 431 KGIYKEHTSVVNSITDLSARYGVAGE--------DDEVILVFSAYVFEPFVRQMLMALTT 482 Query: 168 GSAMVIMR---KFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASI-RMVMS 335 G+++ I+ KFD L+ ++ H +T ++ E G S+ RM++ Sbjct: 483 GNSLAIISDEDKFDPDTLIPFIQKHKVTYIHATSSVLQEY------DFGSCPSLKRMILV 536 Query: 336 G---AAPMGKELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVV 506 G P + L+ F ++I N YG TE+ V A L + + K S G V Sbjct: 537 GENLTEPRYEALRQRFKSRILNE-----YGFTESAFVTA--LNIFEPTSQRKDMSLGRPV 589 Query: 507 RNAGLKIVDPDTGASLGR---NQPGEICIRGEQIMKGYLNDPESTK 635 RN I+D A+L R GE+ I G I +GY+N E T+ Sbjct: 590 RNVKCYILD----ANLKRVPIGVTGELHIGGLGISRGYMNREELTR 631
>LGRD_BREPA (Q70LM4) Linear gramicidin synthetase subunit D [Includes:| ATP-dependent tryptophan adenylase (TrpA) (Tryptophan activase); ATP-dependent D-leucine adenylase (D-LeuA) (D-Leucine activase); Leucine racemase [ATP-hydrolyzing] (EC 5.1.1.-); ATP-d Length = 5085 Score = 42.4 bits (98), Expect = 0.001 Identities = 54/213 (25%), Positives = 92/213 (43%), Gaps = 3/213 (1%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGVM+ H S I +D + + +L S++ V++A L AG+ +V Sbjct: 620 KGVMIEHHSAINLAYALIDAFD----IQPTSRVLQFTSFSFDVSVSEVVMA-LLAGATLV 674 Query: 183 IMRKFDI---GALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMG 353 I + + L+++++ IT V + +A P DL ++ ++ G AP Sbjct: 675 IEDRESLLPGPELIQVLQEQRITTVSMVSSV---LAALPDADLPDLHTL--IVGGEAP-S 728 Query: 354 KELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVD 533 +EL + P YG TEA M L A + + G + NA + ++D Sbjct: 729 RELVARYA---PGRQFFNCYGPTEATVCSTMMLCQAG----MNNPPIGRPIANATVYVLD 781 Query: 534 PDTGASLGRNQPGEICIRGEQIMKGYLNDPEST 632 + + PGE+ I G+ + +GY N PE T Sbjct: 782 ANLNP-VPVGVPGELYIGGKGLARGYWNRPELT 813 Score = 35.0 bits (79), Expect = 0.20 Identities = 42/142 (29%), Positives = 66/142 (46%), Gaps = 6/142 (4%) Frame = +3 Query: 228 AHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKELQDAFMAKIPNAVLGQ 407 A ITV+ F+P + E + + GD A +R +++G G +L KIP ++ Q Sbjct: 1749 ASNITVS-FLPTPLTESMLALE-WPGDTA-LRYMLTG----GDKLHHYPSEKIPFTLVNQ 1801 Query: 408 GYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGASLGRNQP------ 569 YG TE V+A KE + + + G + N + I+D QP Sbjct: 1802 -YGPTE-NTVVATAGIVPKEAGQTAAPTIGRPIDNVQVYILD-------AHRQPVPVGVS 1852 Query: 570 GEICIRGEQIMKGYLNDPESTK 635 GE+ I G + +GYLN P+ T+ Sbjct: 1853 GELYIGGSSLARGYLNRPDLTQ 1874
>ACSL3_HUMAN (O95573) Long-chain-fatty-acid--CoA ligase 3 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 3) (LACS 3) Length = 720 Score = 42.4 bits (98), Expect = 0.001 Identities = 31/116 (26%), Positives = 53/116 (45%), Gaps = 3/116 (2%) Frame = +3 Query: 315 SIRMVMSGAAPMGKELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSC 494 +IR+++ G AP+ Q FM +GQGYG+TE+ + E + +G Sbjct: 444 NIRLLLCGGAPLSATTQ-RFMNICFCCPVGQGYGLTESAGAGTI-----SEVWDYNTGRV 497 Query: 495 GTVVRNAGLKIVDPDTGASLGRNQP---GEICIRGEQIMKGYLNDPESTKNTIDKD 653 G + +K+ + + G ++P GEI I G+ + GY + TK +D Sbjct: 498 GAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQSVTMGYYKNEAKTKADFSED 553
>LGRC_BREPA (Q70LM5) Linear gramicidin synthetase subunit C [Includes:| ATP-dependent valine adenylase (ValA) (Valine activase); ATP-dependent D-valine adenylase (D-ValA) (D-valine activase); Valine racemase [ATP-hydrolyzing] (EC 5.1.1.-); ATP-dependent tr Length = 7756 Score = 42.4 bits (98), Expect = 0.001 Identities = 51/213 (23%), Positives = 91/213 (42%), Gaps = 3/213 (1%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGVM+ H S++ ++ + +L S++ +++A L AG+A+V Sbjct: 3220 KGVMVEHHSVVNLAHALIEA----FRIQPSSRVLQFTSFSFDVSVSEIVMA-LLAGAALV 3274 Query: 183 IMRKFDI---GALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMG 353 I + + L+ +++ IT V ++ + A DL ++ ++ G Sbjct: 3275 IEDREVLLPGPELISVLQQKRITTVSMVSSVLAALP------AADLPDLQTLIVGGEAPS 3328 Query: 354 KELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVD 533 +EL + + YG TEA M L A +KS G + NA L ++D Sbjct: 3329 RELVARYADR---RQFFNCYGPTEATVCSTMMLCNAG----MKSAPIGRPLANATLYVLD 3381 Query: 534 PDTGASLGRNQPGEICIRGEQIMKGYLNDPEST 632 + + PGE+ I G+ + +GY N PE T Sbjct: 3382 ANQ-KPVPVGVPGELYIGGKGLARGYWNRPELT 3413 Score = 35.8 bits (81), Expect = 0.12 Identities = 53/220 (24%), Positives = 83/220 (37%), Gaps = 10/220 (4%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQ-----QVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRA 167 KGVM+ HRS+I Q+D + L F F S ++ L A Sbjct: 5799 KGVMIEHRSVINLAYDLIRHFQIDATSRVLQFIS----------FSFDVSVSEIVMSLLA 5848 Query: 168 GSAMVIMRKFDIGALVELVRA---HGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSG 338 G+ +VI + + EL+R IT V ++ + ++ DL +R ++ G Sbjct: 5849 GATLVIEDRESLLPGPELIRVLQEQRITTFAMVSSVLAALPEA------DLPDLRTIIVG 5902 Query: 339 AAPMGKELQDAFMAKIPNAVLGQGYGMTEAG--PVLAMCLAFAKEPFKVKSGSCGTVVRN 512 +EL + YG TE L C K P G + N Sbjct: 5903 GEAPSRELVARYAT---GRQFINCYGPTETTVTATLKHCQDDGKNP------PIGRPIAN 5953 Query: 513 AGLKIVDPDTGASLGRNQPGEICIRGEQIMKGYLNDPEST 632 + ++D + PGE+ I G+ + +GY N PE T Sbjct: 5954 TTVYVLDAHL-QPVPIGVPGELYIGGKGVARGYWNRPELT 5992 Score = 34.7 bits (78), Expect = 0.27 Identities = 37/136 (27%), Positives = 65/136 (47%) Frame = +3 Query: 228 AHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKELQDAFMAKIPNAVLGQ 407 A GIT++ F+P + E + + + A +R +++G G +L D A +P VL Sbjct: 4344 ASGITIS-FLPTPLAERLLTLEWPSD--AKLRYMLTG----GDKLHDYPPATLP-FVLAN 4395 Query: 408 GYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGASLGRNQPGEICIR 587 YG TE V+A +V + S G + N + ++D + GE+ I Sbjct: 4396 QYGPTE-NAVVATAGIVPAAAGQVSAPSIGRPIDNVQVYVLDEKL-QPVPIGVAGELYIA 4453 Query: 588 GEQIMKGYLNDPESTK 635 G+ + +GYL+ P+ T+ Sbjct: 4454 GDSLARGYLHRPDLTR 4469 Score = 33.5 bits (75), Expect = 0.59 Identities = 38/136 (27%), Positives = 63/136 (46%) Frame = +3 Query: 228 AHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKELQDAFMAKIPNAVLGQ 407 A GIT++ F+P + E S V A++R V++G G +L +P ++ Q Sbjct: 6928 AEGITIS-FLPTPLAESMLS--VDWPSHAALRYVLTG----GDKLHHYPAEHVPFTLVNQ 6980 Query: 408 GYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGASLGRNQPGEICIR 587 YG TE V+A A + +V S G + N + I+D + + GE+ I Sbjct: 6981 -YGPTE-NAVVATAGIVAVQAGQVTPPSIGRPIDNVQVYILD-EQRQPVPIGVTGELYIA 7037 Query: 588 GEQIMKGYLNDPESTK 635 G + +GY P+ T+ Sbjct: 7038 GSSLARGYYKRPDLTQ 7053 Score = 33.5 bits (75), Expect = 0.59 Identities = 46/213 (21%), Positives = 83/213 (38%), Gaps = 3/213 (1%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV++ HR ++ V +N N E+ + + + L G+ +V Sbjct: 1693 KGVLVAHRGIVRLV------KNTNYVTITEEDVFLQASTVSFDAATFEIWGALLNGAKLV 1746 Query: 183 IMRKFDIGALVELVRA---HGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMG 353 +M D+ +L EL A H +T + + A L +R ++ G + Sbjct: 1747 LMPP-DLPSLDELGEAIVQHKVTTLWLTAGLFSIMVDH---NADYLRGVRQLLVGGDVVS 1802 Query: 354 KELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVD 533 +A + + GYG TE C + ++ S G + N + ++D Sbjct: 1803 VPHVRKVLA-LDGVTVINGYGPTE-NTTFTCCYPVTELAEEITSFPIGRPISNTTVYVLD 1860 Query: 534 PDTGASLGRNQPGEICIRGEQIMKGYLNDPEST 632 + + GE+ I G+ + GYLN+PE T Sbjct: 1861 KNR-QPVPLGVAGELYIGGDGLASGYLNNPELT 1892
>DLTA_STRR6 (P0A399) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 516 Score = 42.0 bits (97), Expect = 0.002 Identities = 26/84 (30%), Positives = 40/84 (47%) Frame = +3 Query: 381 KIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGASLGR 560 + PNA + YG TEA L+ + +K G ++ I+D + G L Sbjct: 290 RFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADSPTFIIDEE-GNKLPN 348 Query: 561 NQPGEICIRGEQIMKGYLNDPEST 632 + GEI + G + KGY+N+PE T Sbjct: 349 GEQGEIIVSGPAVSKGYMNNPEKT 372
>DLTA_STRPN (P0A398) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 516 Score = 42.0 bits (97), Expect = 0.002 Identities = 26/84 (30%), Positives = 40/84 (47%) Frame = +3 Query: 381 KIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGASLGR 560 + PNA + YG TEA L+ + +K G ++ I+D + G L Sbjct: 290 RFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADSPTFIIDEE-GNKLPN 348 Query: 561 NQPGEICIRGEQIMKGYLNDPEST 632 + GEI + G + KGY+N+PE T Sbjct: 349 GEQGEIIVSGPAVSKGYMNNPEKT 372
>ACSL4_MOUSE (Q9QUJ7) Long-chain-fatty-acid--CoA ligase 4 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 4) (LACS 4) (mACS4) Length = 711 Score = 41.6 bits (96), Expect = 0.002 Identities = 36/122 (29%), Positives = 55/122 (45%), Gaps = 8/122 (6%) Frame = +3 Query: 315 SIRMVMSGAAPMGKELQDAFMAKIPNAVLGQGYGMTE---AGPVLAMCLAFAKEPFKVKS 485 ++RM++ G AP+ + FM +GQGYG+TE AG V E + Sbjct: 435 NVRMMLYGGAPLSPQTH-RFMNVCLCCPIGQGYGLTESCGAGTVT--------EVTDYTT 485 Query: 486 GSCGTVVRNAGLKIVDPDTGASLGRNQP---GEICIRGEQIMKGYLNDPESTKN--TIDK 650 G G + +K+ D G ++P GEI I G+ I GY + E T +D+ Sbjct: 486 GRVGAPLICCEIKLKDWQEGGYTVHDKPNPRGEIVIGGQNISMGYFKNEEKTAEDYCVDE 545 Query: 651 DG 656 +G Sbjct: 546 NG 547
>SID2_USTMA (O43103) Ferrichrome siderophore peptide synthetase (EC 6.-.-.-)| Length = 3947 Score = 41.6 bits (96), Expect = 0.002 Identities = 54/216 (25%), Positives = 97/216 (44%), Gaps = 6/216 (2%) Frame = +3 Query: 3 KGVMLTHRSLITSVA---QQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGS 173 KG +LT +L +V + E P + + L F ++ L L LR G+ Sbjct: 1557 KGCLLTQANLAAAVEGFYYNYEKEAPGSFESRARFLARSAEAFDVHLLEIFL--SLRVGA 1614 Query: 174 AMVI-MRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPM 350 +V R + + + +T A VP + +K ++ + S+R+++ G + Sbjct: 1615 TIVTGPRALIHDDIAKTMSTLEVTHACVVPSLF--FSKGKRIEPSVVPSLRVLIIGGEAL 1672 Query: 351 GKELQDAFMAK-IPNAVLGQGYGMTEAGPVLAMCLAFAKE-PFKVKSGSCGTVVRNAGLK 524 ++L + ++ V+ YG +EA ++ K P + + GT + LK Sbjct: 1673 TQDLCQIWGSEGSERPVVLNAYGPSEATIGNSVARVSKKSRPSNIGAPFPGT--QYLVLK 1730 Query: 525 IVDPDTGASLGRNQPGEICIRGEQIMKGYLNDPEST 632 V+ +L R +PGE+ I GEQ+ KGYLN P+S+ Sbjct: 1731 DVNGQLVPTL-RGEPGELYIGGEQVAKGYLNRPDSS 1765
>ACSL3_MOUSE (Q9CZW4) Long-chain-fatty-acid--CoA ligase 3 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 3) (LACS 3) Length = 720 Score = 41.6 bits (96), Expect = 0.002 Identities = 37/128 (28%), Positives = 59/128 (46%), Gaps = 10/128 (7%) Frame = +3 Query: 315 SIRMVMSGAAPMGKELQDAFMAKIPNAVLGQGYGMTE---AGPVLAMCLAFAKEPFKVKS 485 +IR+++ G AP+ Q FM +GQGYG+TE AG + E + + Sbjct: 444 NIRLLLCGGAPLSATTQ-RFMNICFCCPVGQGYGLTESTGAGTIT--------EVWDYNT 494 Query: 486 GSCGTVVRNAGLKIVDPDTGASLGRNQP---GEICIRGEQIMKGYLNDPESTKNTI--DK 650 G G + +K+ + + G ++P GEI I G+ + GY + TK D+ Sbjct: 495 GRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQNVTMGYYKNEAKTKTDFFEDE 554 Query: 651 DG--WLHT 668 +G WL T Sbjct: 555 NGQRWLCT 562
>SRFAA_BACSU (P27206) Surfactin synthetase subunit 1| Length = 3588 Score = 41.6 bits (96), Expect = 0.002 Identities = 55/232 (23%), Positives = 92/232 (39%), Gaps = 15/232 (6%) Frame = +3 Query: 3 KGVMLTHRSL--ITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSA 176 KGVM+ HR + + QQ ++P + + + LP FH + + A L G Sbjct: 615 KGVMIEHRQVHHLVESLQQTIYQSPT-----QTLPMAFLPPFHFDASVKQIFASLLLGQT 669 Query: 177 MVIMRKFDI---GALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRM--VMSGA 341 + I+ K + AL R + I P + +A AGD +++ ++ G Sbjct: 670 LYIVPKKTVTNGAALTAYYRKNSIEATDGTPAHLQMLA-----AAGDFEGLKLKHMLIGG 724 Query: 342 APMGKELQDAFMAKIPNAV----LGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVR 509 + + D + A L YG TE ++ + + G + Sbjct: 725 EGLSSVVADKLLKLFKEAGTAPRLTNVYGPTETCVDASVHPVIPENAVQSAYVPIGKALG 784 Query: 510 NAGLKIVDPDTGASLGRNQP----GEICIRGEQIMKGYLNDPESTKNTIDKD 653 N L I+D GR QP GE+ I G+ + +GYL+ PE T+ +D Sbjct: 785 NNRLYILDQK-----GRLQPEGVAGELYIAGDGVGRGYLHLPELTEEKFLQD 831 Score = 39.3 bits (90), Expect = 0.011 Identities = 49/215 (22%), Positives = 90/215 (41%), Gaps = 4/215 (1%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLP-LFHIYSLNSVLLAGLRAGSAM 179 KG ++TH +++ +V E L ++D +L L +F + + + L G+ + Sbjct: 1662 KGNIVTHANILRTVK-----ETNYLSITEQDTILGLSNYVFDAFMFD--MFGSLLNGAKL 1714 Query: 180 VIMRK---FDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPM 350 V++ K D+ L ++ I++ + + + L+++R +M G Sbjct: 1715 VLIPKETVLDMARLSRVIERENISILMITTALFHLLV---DLNPACLSTLRKIMFGGERA 1771 Query: 351 GKELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIV 530 E + + L YG +E+ V A + S G V N + I+ Sbjct: 1772 SVEHVRKALQTVGKGKLLHMYGPSES-TVFATYHPVDELEEHTLSVPIGKPVSNTEVYIL 1830 Query: 531 DPDTGASLGRNQPGEICIRGEQIMKGYLNDPESTK 635 D TG GE+C+ GE ++KGY N PE T+ Sbjct: 1831 DR-TGHVQPAGIAGELCVTGEGLVKGYYNRPELTE 1864 Score = 32.3 bits (72), Expect = 1.3 Identities = 33/147 (22%), Positives = 60/147 (40%) Frame = +3 Query: 192 KFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKELQDA 371 + DI L + +G+T+ F+P + E Q + S+R++++G + + ++ Sbjct: 2769 RLDIVRLNDYFETNGVTIT-FLPTQLAE-----QFMELENTSLRVLLTGGDKLKRAVKKP 2822 Query: 372 FMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGAS 551 + L YG TE V +E S S G + N + I+ Sbjct: 2823 Y-------TLVNNYGPTENTVVATSAEIHPEEG----SLSIGRAIANTRVYILGEGNQVQ 2871 Query: 552 LGRNQPGEICIRGEQIMKGYLNDPEST 632 GE+C+ G + +GYLN + T Sbjct: 2872 -PEGVAGELCVAGRGLARGYLNREDET 2897
>ACSL3_RAT (Q63151) Long-chain-fatty-acid--CoA ligase 3 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 3) (LACS 3) (Brain acyl-CoA synthtase II) Length = 720 Score = 40.4 bits (93), Expect = 0.005 Identities = 37/128 (28%), Positives = 59/128 (46%), Gaps = 10/128 (7%) Frame = +3 Query: 315 SIRMVMSGAAPMGKELQDAFMAKIPNAVLGQGYGMTE---AGPVLAMCLAFAKEPFKVKS 485 +IR+++ G AP+ Q FM +GQGYG+TE AG + E + + Sbjct: 444 NIRVLLCGGAPLSATTQ-RFMNICFCCPVGQGYGLTESTGAGTIT--------EVWDYNT 494 Query: 486 GSCGTVVRNAGLKIVDPDTGASLGRNQP---GEICIRGEQIMKGYLNDPESTKNTI--DK 650 G G + +K+ + + G ++P GEI I G+ + GY + TK D+ Sbjct: 495 GRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQNVTMGYYKNEAKTKADFFEDE 554 Query: 651 DG--WLHT 668 +G WL T Sbjct: 555 NGQRWLCT 562
>ESYN_FUSEQ (Q00869) Enniatin synthetase [Includes: N-methylcyclopeptide| synthetase (EC 6.3.2.-); S-adenosyl-L-methionine-dependent N-methyltransferase (EC 2.1.1.-)] Length = 3131 Score = 40.4 bits (93), Expect = 0.005 Identities = 51/216 (23%), Positives = 92/216 (42%), Gaps = 4/216 (1%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFH--IYSLNSVLLAGLRAGSA 176 KGVM+ HR+++ + V +N + + P F I+ +N +LL G G+ Sbjct: 1716 KGVMIEHRAIV----RLVKSDNFPGFPSPARMSNVFNPAFDGAIWEINWMLLNG---GTV 1768 Query: 177 MVI--MRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPM 350 + I + D L + + A F P ++ + +L + ++ G Sbjct: 1769 VCIDYLTTLDGKELAAVFAKERVNAAFFAPAMLKLYLVDAREALKNLDFL--IVGGERFD 1826 Query: 351 GKELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIV 530 KE +A + + YG TEAG +++ C K+ G + N+G ++ Sbjct: 1827 TKEAVEAM--PLVRGKIANIYGPTEAG-IISTCYNIPKDEAYTNGVPIGGSIYNSGAYVM 1883 Query: 531 DPDTGASLGRNQPGEICIRGEQIMKGYLNDPESTKN 638 DP+ +G GE+ + G+ + +GY N PE KN Sbjct: 1884 DPNQQL-VGLGVMGELVVTGDGVGRGYTN-PELNKN 1917
>SRFAB_BACSU (Q04747) Surfactin synthetase subunit 2| Length = 3587 Score = 40.0 bits (92), Expect = 0.006 Identities = 48/220 (21%), Positives = 85/220 (38%), Gaps = 3/220 (1%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGVM+ H+S++ V +N E+ + + + L G+A+ Sbjct: 622 KGVMIEHKSILRLV------KNAGYVPVTEEDAMAQTGAVSFDAGTFEVFGALLNGAALY 675 Query: 183 IMRK---FDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMG 353 ++K D +R IT P+ ++A AG ++R ++ G + Sbjct: 676 PVKKRHVLDAKQFAAFLREQSITTMWLTSPLFNQLAAKD---AGMFGTLRHLIIGGDALV 732 Query: 354 KELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVD 533 + P+ L GYG TE +F + S G + N+ I+D Sbjct: 733 PHIVSKVKQASPSLSLWNGYGPTEN---TTFSTSFLIDREYGGSIPIGKPIGNSTAYIMD 789 Query: 534 PDTGASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKD 653 + PGE+C+ G + +GY+N PE T+ +D Sbjct: 790 -EQQCLQPIGAPGELCVGGIGVARGYVNLPELTEKQFLED 828 Score = 32.3 bits (72), Expect = 1.3 Identities = 33/147 (22%), Positives = 60/147 (40%) Frame = +3 Query: 192 KFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKELQDA 371 + DI L + +G+T+ F+P + E Q + S+R++++G + + ++ Sbjct: 2768 RLDIVRLNDYFETNGVTIT-FLPTQLAE-----QFMELENTSLRVLLTGGDKLKRAVKKP 2821 Query: 372 FMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGAS 551 + L YG TE V +E S S G + N + I+ Sbjct: 2822 Y-------TLVNNYGPTENTVVATSAEIHPEEG----SLSIGRAIANTRVYILGEGNQVQ 2870 Query: 552 LGRNQPGEICIRGEQIMKGYLNDPEST 632 GE+C+ G + +GYLN + T Sbjct: 2871 -PEGVAGELCVAGRGLARGYLNREDET 2896
>HMWP2_YEREN (P48633) High-molecular-weight protein 2 (HMWP2)| Length = 2035 Score = 39.7 bits (91), Expect = 0.008 Identities = 58/233 (24%), Positives = 95/233 (40%), Gaps = 11/233 (4%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV+++HR + + N D +L L L S+ + LRAG A+V Sbjct: 720 KGVVISHRGALNTCCDI----NTRYQVGPHDRVLALSALHFDLSVYDIF-GVLRAGGALV 774 Query: 183 IM---RKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLA-SIRMVMSGAAPM 350 ++ ++ D A EL++ H +T+ VP + + + A ++R VM + Sbjct: 775 MVMENQRRDPHAWCELIQRHQVTLWNSVPALFDMLLTWCEGFADATPENLRAVMLSGDWI 834 Query: 351 GKELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIV 530 G +L + A P G TEA + + P +S G + N ++V Sbjct: 835 GLDLPARYRAFRPQGQFIAMGGATEAS-IWSNACEIHDVPAHWRSIPYGFPLTNQRYRVV 893 Query: 531 DPDTGASLGRNQP----GEICIRGEQIMKGYLND---PESTKNTIDKDGWLHT 668 D GR+ P GE+ I G + +GY ND E T+ + W T Sbjct: 894 D-----ERGRDCPDWVSGELWIGGIGVAEGYFNDSLRSEQQFLTLPDERWYRT 941
>DLTA_STRA5 (P59591) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 511 Score = 39.7 bits (91), Expect = 0.008 Identities = 28/85 (32%), Positives = 41/85 (48%), Gaps = 1/85 (1%) Frame = +3 Query: 381 KIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKV-KSGSCGTVVRNAGLKIVDPDTGASLG 557 + P A + YG TEA L+ +A E + K G ++ ++D + G L Sbjct: 286 RFPKARIVNAYGPTEATVALS-AVAITDEMLETCKRLPIGYTKDDSPTYVIDEE-GHKLP 343 Query: 558 RNQPGEICIRGEQIMKGYLNDPEST 632 + GEI I G + KGYLN+PE T Sbjct: 344 NGEQGEIIIAGPAVSKGYLNNPEKT 368
>DLTA_STRA3 (Q8VM67) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 511 Score = 39.7 bits (91), Expect = 0.008 Identities = 28/85 (32%), Positives = 41/85 (48%), Gaps = 1/85 (1%) Frame = +3 Query: 381 KIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKV-KSGSCGTVVRNAGLKIVDPDTGASLG 557 + P A + YG TEA L+ +A E + K G ++ ++D + G L Sbjct: 286 RFPKARIVNAYGPTEATVALS-AVAITDEMLETCKRLPIGYTKDDSPTYVIDEE-GHKLP 343 Query: 558 RNQPGEICIRGEQIMKGYLNDPEST 632 + GEI I G + KGYLN+PE T Sbjct: 344 NGEQGEIIIAGPAVSKGYLNNPEKT 368
>FAD25_MYCTU (Q50586) Putative fatty-acid--CoA ligase fadD25 (EC 6.2.1.-)| (Acyl-CoA synthetase) Length = 583 Score = 39.3 bits (90), Expect = 0.011 Identities = 57/249 (22%), Positives = 103/249 (41%), Gaps = 37/249 (14%) Frame = +3 Query: 6 GVMLTHRSLITSVAQQVDGENPNLYFRKE---DVLLCLLPLFHIYSLNSVLLAGLRAGSA 176 GVM+++++L + +Q+ +Y + ++ LP +H L+ + AG Sbjct: 184 GVMVSNKNLFANF-EQIMTSYYGVYGKVAPPGSTVVSWLPFYHDMGFVLGLILPILAGIP 242 Query: 177 MVIMRKFDIGAL------VELVRAHGI--TVAP-FVPPIVVEIAKSPQVTAGDLASIRMV 329 V+ IG L ++++ ++ + T AP F + K + DL + + Sbjct: 243 AVLTSP--IGFLQRPARWIQMLASNTLAFTAAPNFAFDLASRKTKDEDMEGLDLGGVHGI 300 Query: 330 MSGAAPMGKELQDAFMAKI------PNAVLGQGYGMTEAGPVLAMCLAFAK------EPF 473 ++G+ + F+ + P A+ YGM EA +A A +P Sbjct: 301 LNGSERVQPVTLKRFIDRFAPFNLDPKAIR-PSYGMAEATVYVATRKAGQPPKIVQFDPQ 359 Query: 474 KVKSGSC-------GTVVRNAGL------KIVDPDTGASLGRNQPGEICIRGEQIMKGYL 614 K+ G GT + + G+ +IVDPDTG GEI + G+ + GY Sbjct: 360 KLPDGQAERTESDGGTPLVSYGIVDTQLVRIVDPDTGIERPAGTIGEIWVHGDNVAIGYW 419 Query: 615 NDPESTKNT 641 PE+T+ T Sbjct: 420 QKPEATERT 428
>FAT1_YEAST (P38225) Very long-chain fatty acid transport protein| Length = 669 Score = 39.3 bits (90), Expect = 0.011 Identities = 51/231 (22%), Positives = 91/231 (39%), Gaps = 25/231 (10%) Frame = +3 Query: 36 TSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMVIMRKFDIGALV 215 +SV QV G L+ E + +PLFH + A L G + + KF Sbjct: 274 SSVGCQVFGHV--LHMTNESTVFTAMPLFHSTAALLGACAILSHGGCLALSHKFSASTFW 331 Query: 216 ELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKELQDAFMAKIPNA 395 + V G T +V + + +P + +++ + ++ F + Sbjct: 332 KQVYLTGATHIQYVGEVCRYLLHTPISKYEKMHKVKVAYGNG--LRPDIWQDFRKRFNIE 389 Query: 396 VLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSC---GTVVR-----NAGLKIVDPDTGAS 551 V+G+ Y TEA F K F + G+C GT+++ L +DP+ + Sbjct: 390 VIGEFYAATEAP---FATTTFQKGDFGI--GACRNYGTIIQWFLSFQQTLVRMDPNDDSV 444 Query: 552 LGRN-----------QPGEICIR------GEQIMKGYLNDPESTKNTIDKD 653 + RN +PGE+ +R E +GYL + + TK+ + +D Sbjct: 445 IYRNSKGFCEVAPVGEPGEMLMRIFFPKKPETSFQGYLGNAKETKSKVVRD 495
>DLTA_STRP8 (Q8P0J9) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 512 Score = 39.3 bits (90), Expect = 0.011 Identities = 26/84 (30%), Positives = 38/84 (45%) Frame = +3 Query: 381 KIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGASLGR 560 + P+A + YG TEA L+ + G ++ I+D D G L Sbjct: 286 RFPSAKIINAYGPTEATVALSAIEITREMVDNYTRLPIGYPKPDSPTYIIDED-GKELAS 344 Query: 561 NQPGEICIRGEQIMKGYLNDPEST 632 + GEI + G + KGYLN+PE T Sbjct: 345 GEQGEIIVTGPAVSKGYLNNPEKT 368
>DLTA_STRP6 (Q5XBN5) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 512 Score = 39.3 bits (90), Expect = 0.011 Identities = 26/84 (30%), Positives = 38/84 (45%) Frame = +3 Query: 381 KIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGASLGR 560 + P+A + YG TEA L+ + G ++ I+D D G L Sbjct: 286 RFPSAKIINAYGPTEATVALSAIEITREMVDNYTRLPIGYPKPDSPTYIIDED-GKELSS 344 Query: 561 NQPGEICIRGEQIMKGYLNDPEST 632 + GEI + G + KGYLN+PE T Sbjct: 345 GEQGEIIVTGPAVSKGYLNNPEKT 368
>DLTA_STRP3 (Q8K744) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 512 Score = 39.3 bits (90), Expect = 0.011 Identities = 26/84 (30%), Positives = 38/84 (45%) Frame = +3 Query: 381 KIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGASLGR 560 + P+A + YG TEA L+ + G ++ I+D D G L Sbjct: 286 RFPSAKIINAYGPTEATVALSAIEITREMVDNYTRLPIGYPKPDSPTYIIDED-GKELSS 344 Query: 561 NQPGEICIRGEQIMKGYLNDPEST 632 + GEI + G + KGYLN+PE T Sbjct: 345 GEQGEIIVTGPAVSKGYLNNPEKT 368
>DLTA_STRP1 (Q99ZA6) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 512 Score = 39.3 bits (90), Expect = 0.011 Identities = 26/84 (30%), Positives = 38/84 (45%) Frame = +3 Query: 381 KIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGASLGR 560 + P+A + YG TEA L+ + G ++ I+D D G L Sbjct: 286 RFPSAKIINAYGPTEATVALSAIEITREMVDNYTRLPIGYPKPDSPTYIIDED-GKELSS 344 Query: 561 NQPGEICIRGEQIMKGYLNDPEST 632 + GEI + G + KGYLN+PE T Sbjct: 345 GEQGEIIVTGPAVSKGYLNNPEKT 368
>S27A3_HUMAN (Q5K4L6) Long-chain fatty acid transport protein 3 (EC 6.2.1.-)| (Fatty acid transport protein 3) (FATP-3) (Very long-chain acyl-CoA synthetase homolog 3) (VLCS-3) (Solute carrier family 27 member 3) Length = 683 Score = 38.9 bits (89), Expect = 0.014 Identities = 28/114 (24%), Positives = 53/114 (46%), Gaps = 1/114 (0%) Frame = +3 Query: 87 KEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMVIMRKFDIGALVELVRAHGITVAPFVPPI 266 +EDV+ LPL+H+ ++ + G+ +V+ KF G E + H +TV ++ + Sbjct: 319 QEDVIYLALPLYHMSGSLLGIVGCMGIGATVVLKSKFSAGQFWEDCQQHRVTVFQYIGEL 378 Query: 267 VVEIAKSPQVTAGDLASIRM-VMSGAAPMGKELQDAFMAKIPNAVLGQGYGMTE 425 + P A +R+ V SG P + + F+ + + + YG+TE Sbjct: 379 CRYLVNQPPSKAERGHKVRLAVGSGLRP---DTWERFVRRFGPLQVLETYGLTE 429
>DLTA_BACSU (P39581) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 503 Score = 38.5 bits (88), Expect = 0.018 Identities = 34/142 (23%), Positives = 55/142 (38%) Frame = +3 Query: 210 LVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKELQDAFMAKIP 389 L E ++ G+ V P V P + L M + + A + + P Sbjct: 226 LFEELKKSGLNVWTSTPSFVQMCLMDPGFSQDLLPHADTFMFCGEVLPVSVAKALLERFP 285 Query: 390 NAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGASLGRNQP 569 A + YG TEA + + +S G + + I+D + G L + Sbjct: 286 KAKIFNTYGPTEATVAVTSVEITNDVISRSESLPVGFAKPDMNIFIMDEE-GQPLPEGEK 344 Query: 570 GEICIRGEQIMKGYLNDPESTK 635 GEI I G + +GYL +PE T+ Sbjct: 345 GEIVIAGPSVSRGYLGEPELTE 366
>FAD21_MYCLE (P54200) Putative fatty-acid--CoA ligase fadD21 (EC 6.2.1.-)| (Acyl-CoA synthetase) Length = 579 Score = 38.1 bits (87), Expect = 0.024 Identities = 50/245 (20%), Positives = 93/245 (37%), Gaps = 33/245 (13%) Frame = +3 Query: 6 GVMLTHRSLITSVAQ-QVDGENPNLYFRKEDV-LLCLLPLFHIYSLNSVLLAGLRAG--- 170 GVM+THR+L+ + Q D P D+ ++ LP +H L ++A + G Sbjct: 180 GVMVTHRNLMVNFQQLMADYFAPTNGVAPLDLTIVSWLPFYHDMGLVLGVVAPILGGWRS 239 Query: 171 ---SAMVIMRKFDIGALVELVRAHGITVAP-FVPPIVVEIAKSPQVTAGDLASIRMVMSG 338 S + +++ +H + P F + + DL + + ++SG Sbjct: 240 ELTSPISFLQRPARWIQAMATSSHPFSAGPNFAFELAARRTSDADIAGLDLGACQGIISG 299 Query: 339 AAPMGKELQDAFMAK-----------IPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKS 485 + + + F + +P+ L +G + P + EP K+ Sbjct: 300 SERIHPATLNRFSDRFARINFRDDMMLPSYGLAEGTVYAASRPKGSSPEVVYFEPAKLSE 359 Query: 486 GSCGTVVRNAG-------------LKIVDPDTGASLGRNQPGEICIRGEQIMKGYLNDPE 626 G+ G ++IVD DT + GEI + G+ + +GY + PE Sbjct: 360 GTVKRCEARTGAPLLSYGTPKSPIVRIVDSDTCIECPTGRVGEIWLHGDNVAEGYWHKPE 419 Query: 627 STKNT 641 T+ T Sbjct: 420 ETQRT 424
>FAD28_MYCBO (Q02278) Putative fatty-acid--CoA ligase fadD28 (EC 6.2.1.-)| (Acyl-CoA synthetase) Length = 580 Score = 38.1 bits (87), Expect = 0.024 Identities = 56/251 (22%), Positives = 93/251 (37%), Gaps = 39/251 (15%) Frame = +3 Query: 6 GVMLTHRSLITSVAQQVDGENPNLYFRKED-------VLLCLLPLFHIYSLNSVLLAGLR 164 GV+++H+++ + Q + G YF D L+ LP +H L + A + Sbjct: 180 GVVMSHQNVRVNFEQLMSG-----YFADTDGIPPPNSALVSWLPFYHDMGLVIGICAPIL 234 Query: 165 AGSAMVIMRKFDI----GALVELVRA--HGITVAP-FVPPIVVEIAKSPQVTAGDLASIR 323 G V+ + L+ + H + AP F + + DL +I Sbjct: 235 GGYPAVLTSPVSFLQRPARWMHLMASDFHAFSAAPNFAFELAARRTTDDDMAGRDLGNIL 294 Query: 324 MVMSGA----APMGKELQDAFMA-KIPNAVLGQGYGMTEAGPVLAMCLAFAKEP----FK 476 ++SG+ A K D F + V+ YG+ EA +A + P F Sbjct: 295 TILSGSERVQAATIKRFADRFARFNLQERVIRPSYGLAEATVYVATSKP-GQPPETVDFD 353 Query: 477 VKSGSCGTVVRNAG----------------LKIVDPDTGASLGRNQPGEICIRGEQIMKG 608 +S S G AG ++IVD DT GEI + G+ + G Sbjct: 354 TESLSAGHAKPCAGGGATSLISYMLPRSPIVRIVDSDTCIECPDGTVGEIWVHGDNVANG 413 Query: 609 YLNDPESTKNT 641 Y P+ ++ T Sbjct: 414 YWQKPDESERT 424
>TYCA_BREPA (P09095) Tyrocidine synthetase 1 (Tyrocidine synthetase I)| [Includes: ATP-dependent D-phenylalanine adenylase (D-PheA) (D-phenylalanine activase); Phenylalanine racemase [ATP-hydrolyzing] (EC 5.1.1.11)] Length = 1088 Score = 38.1 bits (87), Expect = 0.024 Identities = 36/165 (21%), Positives = 68/165 (41%), Gaps = 3/165 (1%) Frame = +3 Query: 147 LLAGLRAGSAMVIMRK---FDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLAS 317 + L +G+++ I+ K D A + + +T+ P + + T + S Sbjct: 229 MFMALLSGASLYILSKQTIHDFAAFEHYLSENELTIITLPPTYLTHL------TPERITS 282 Query: 318 IRMVMSGAAPMGKELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCG 497 +R++++ + L + + K+ YG TE + A V+S G Sbjct: 283 LRIMITAGSASSAPLVNKWKDKLRYI---NAYGPTETS-ICATIWEAPSNQLSVQSVPIG 338 Query: 498 TVVRNAGLKIVDPDTGASLGRNQPGEICIRGEQIMKGYLNDPEST 632 ++N + IV+ D L GE+CI G + +GY N P+ T Sbjct: 339 KPIQNTHIYIVNEDLQL-LPTGSEGELCIGGVGLARGYWNRPDLT 382
>ORA_PLAFN (P16405) Octapeptide-repeat antigen (ORA) (Fragment)| Length = 701 Score = 37.4 bits (85), Expect = 0.041 Identities = 27/117 (23%), Positives = 55/117 (47%), Gaps = 2/117 (1%) Frame = +3 Query: 324 MVMSGAAPMGKELQDAFMAKIPNAVLGQGYGMTEA-GPVLAMCLAFAKEPFKVKSGSCGT 500 ++++G + E+ + ++ + N QGYG+TE+ GP+ F ++ + S G Sbjct: 359 VILNGGGKLSPEVAEG-LSVLLNVKYYQGYGLTESTGPI------FLQDVDDCNTESMGV 411 Query: 501 VVR-NAGLKIVDPDTGASLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 V + K+ + + GE+ I+ + + GY + EST++ DG+ T Sbjct: 412 AVSPSTRYKVRTWEIYKATDTIPKGELLIKSDSMFSGYFLEKESTEHAFTNDGYFKT 468
>S27A3_MOUSE (O88561) Long-chain fatty acid transport protein 3 (EC 6.2.1.-)| (Fatty acid transport protein 3) (FATP-3) (Solute carrier family 27 member 3) Length = 667 Score = 37.4 bits (85), Expect = 0.041 Identities = 28/114 (24%), Positives = 52/114 (45%), Gaps = 1/114 (0%) Frame = +3 Query: 87 KEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMVIMRKFDIGALVELVRAHGITVAPFVPPI 266 +EDV+ LPL+H+ ++ L G+ +V+ KF + + H +TV ++ + Sbjct: 303 QEDVIYLALPLYHMSGSLLGIVGCLGIGATVVLKPKFSASQFWDDCQKHRVTVFQYIGEL 362 Query: 267 VVEIAKSPQVTAGDLASIRM-VMSGAAPMGKELQDAFMAKIPNAVLGQGYGMTE 425 + P A +R+ V SG P + + F+ + + + YGMTE Sbjct: 363 CRYLVNQPPSKAECDHKVRLAVGSGLRP---DTWERFLRRFGPLQILETYGMTE 413
>FAD26_MYCTU (Q10976) Putative fatty-acid--CoA ligase fadD26 (EC 6.2.1.-)| (Acyl-CoA synthetase) Length = 583 Score = 37.0 bits (84), Expect = 0.054 Identities = 56/249 (22%), Positives = 97/249 (38%), Gaps = 35/249 (14%) Frame = +3 Query: 6 GVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMVI 185 GV+++H ++I +V Q + G + ++ LPL+H L + A L A ++ Sbjct: 182 GVIVSHTNVIANVTQSMYGYFGDPAKIPTGTVVSWLPLYHDMGLILGICAPLVARRRAML 241 Query: 186 MRKFDI----GALVELVRAHG--ITVAP-FVPPIVVEIAKSPQVTAGDLASIRMVMSGAA 344 M ++L+ G + AP F + V + DL + ++SG+ Sbjct: 242 MSPMSFLRRPARWMQLLATSGRCFSAAPNFAFELAVRRTSDQDMAGLDLRDVVGIVSGSE 301 Query: 345 PMGKELQDAFMAKI------PNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVK-------- 482 + F+ + P A+ YG+ EA +A A A P V+ Sbjct: 302 RIHVATVRRFIERFAPYNLSPTAIR-PSYGLAEATLYVAAPEAGAA-PKTVRFDYEQLTA 359 Query: 483 --------SGSCGTVVRNAG------LKIVDPDTGASLGRNQPGEICIRGEQIMKGYLND 620 GS GT + + G ++IV+P+T GEI + G+ + GY Sbjct: 360 GQARPCGTDGSVGTELISYGSPDPSSVRIVNPETMVENPPGVVGEIWVHGDHVTMGYWQK 419 Query: 621 PESTKNTID 647 P+ T D Sbjct: 420 PKQTAQVFD 428
>GRSA_ANEMI (P0C061) Gramicidin S synthetase 1 (Gramicidin S synthetase I)| [Includes: ATP-dependent D-phenylalanine adenylase (D-PheA) (D-phenylalanine activase); Phenylalanine racemase [ATP-hydrolyzing] (EC 5.1.1.11)] Length = 1098 Score = 36.2 bits (82), Expect = 0.092 Identities = 43/166 (25%), Positives = 71/166 (42%), Gaps = 4/166 (2%) Frame = +3 Query: 147 LLAGLRAGSAMVIMRKFDIGALVEL---VRAHGITVAPFVPPIVVEIAKSPQVTAGDLAS 317 + L G+++ I+ K I V+ + ITV P VV + P+ + S Sbjct: 241 MFMALLTGASLYIILKDTINDFVKFEQYINQKEITVITLPPTYVVHL--DPE----RILS 294 Query: 318 IRMVMSGAAPMGKELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCG 497 I+ +++ + L + + K+ YG TE + A KE S G Sbjct: 295 IQTLITAGSATSPSLVNKWKEKVTYI---NAYGPTET-TICATTWVATKETIG-HSVPIG 349 Query: 498 TVVRNAGLKIVDPDTGA-SLGRNQPGEICIRGEQIMKGYLNDPEST 632 ++N + IVD + S+G + GE+CI GE + +GY PE T Sbjct: 350 APIQNTQIYIVDENLQLKSVG--EAGELCIGGEGLARGYWKRPELT 393
>DLTA_LACRH (P35854) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 506 Score = 35.8 bits (81), Expect = 0.12 Identities = 25/96 (26%), Positives = 39/96 (40%) Frame = +3 Query: 369 AFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGA 548 A + + P A + YG TEA + + G + + +VD + G Sbjct: 280 ALITRFPKATVYNTYGPTEATVAVTGMAITQAIVDQYPRLPIGYAKPDTNVYVVD-EQGE 338 Query: 549 SLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDG 656 + GE+ I G + KGYLN+P+ T K G Sbjct: 339 QVSAGTEGELMIVGPSVSKGYLNNPDKTAAAFFKAG 374
>ACVS_EMENI (P27742) N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase| (EC 6.3.2.26) (Delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase) (ACV synthetase) (ACVS) Length = 3770 Score = 35.8 bits (81), Expect = 0.12 Identities = 55/222 (24%), Positives = 92/222 (41%), Gaps = 12/222 (5%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQ-----VDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRA 167 KG++ H +++ S+ V G++ E +LL +F + +L L Sbjct: 488 KGILKQHTNVVNSITDLSARYGVTGDH------HEAILLFSAYVFEPFVRQ--MLMALVN 539 Query: 168 GSAMVIM---RKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSG 338 G + ++ K+D L+ +R H IT ++ E S S++ ++ Sbjct: 540 GHLLAMVDDAEKYDAEKLIPFIREHKITYLNGTASVLQEYDFS------SCPSLKRLILV 593 Query: 339 AAPMGKELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSG-SCGTVVRNA 515 + + A N +L + YG TE+ V A+ + EP ++ S G VRN Sbjct: 594 GENLTESRYLALRRHFKNCILNE-YGFTESAFVTALNVF---EPGSARNNTSLGRPVRNV 649 Query: 516 GLKIVDPDTGASLGR---NQPGEICIRGEQIMKGYLNDPEST 632 I++ SL R GE+ I G I KGYLN P+ T Sbjct: 650 KCYILNK----SLKRVPIGATGELHIGGLGISKGYLNRPDLT 687
>GRSA_BREBE (P0C062) Gramicidin S synthetase 1 (Gramicidin S synthetase I)| [Includes: ATP-dependent D-phenylalanine adenylase (D-PheA) (D-phenylalanine activase); Phenylalanine racemase [ATP-hydrolyzing] (EC 5.1.1.11)] Length = 1098 Score = 35.4 bits (80), Expect = 0.16 Identities = 43/166 (25%), Positives = 71/166 (42%), Gaps = 4/166 (2%) Frame = +3 Query: 147 LLAGLRAGSAMVIMRKFDIGALVEL---VRAHGITVAPFVPPIVVEIAKSPQVTAGDLAS 317 + L G+++ I+ K I V+ + ITV P VV + P+ + S Sbjct: 241 MFMALLTGASLYIILKDTINDFVKFEQYINQKEITVITLPPTYVVHL--DPE----RILS 294 Query: 318 IRMVMSGAAPMGKELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCG 497 I+ +++ + L + + K+ YG TE + A KE S G Sbjct: 295 IQTLITAGSATSPSLVNKWKEKVTYI---NAYGPTET-TICATTWVATKETTG-HSVPIG 349 Query: 498 TVVRNAGLKIVDPDTGA-SLGRNQPGEICIRGEQIMKGYLNDPEST 632 ++N + IVD + S+G + GE+CI GE + +GY PE T Sbjct: 350 APIQNTQIYIVDENLQLKSVG--EAGELCIGGEGLARGYWKRPELT 393
>MUC1_YEAST (P08640) Mucin-like protein 1 precursor| Length = 1367 Score = 35.0 bits (79), Expect = 0.20 Identities = 38/154 (24%), Positives = 68/154 (44%) Frame = -2 Query: 547 APVSGSTILSPALRTTVPHDPDLTLNGSLANARHMASTGPASVIPYPCPSTALGILAMKA 368 APV+ ST S + P T + S +ST +S P P PS++ ++ Sbjct: 750 APVTSSTTESSSAPVPTPSS-STTESSSAPVPTPSSSTTESSSAPVPTPSSS----TTES 804 Query: 367 SCSSLPMGAAPDMTMRMDARSPAVTWGLLAISTTMGGTKGATVMPCARTSSTSAPMSNLR 188 S + +P P + + + +P+ T S+T + + T S+SAP+S+ Sbjct: 805 SVAPVP---TPSSSSNITSSAPSST---PFSSSTESSSVPVPTPSSSTTESSSAPVSSST 858 Query: 187 MITIADPARSPASSTELSE*MWNSGSRHSSTSSF 86 + P +P+SS+ ++ +S S+T SF Sbjct: 859 TESSVAPVPTPSSSSNITSSAPSSIPFSSTTESF 892 Score = 31.6 bits (70), Expect = 2.3 Identities = 37/152 (24%), Positives = 65/152 (42%), Gaps = 17/152 (11%) Frame = -2 Query: 547 APVSGST-------ILSPALRTT----VPHDPDLTLNGSLANARHMASTGPASVIPYPCP 401 APV+ ST + +P+ TT P + ++A +ST +S P P P Sbjct: 498 APVTSSTTESSSAPVPTPSSSTTESSSAPAPTPSSSTTESSSAPVTSSTTESSSAPVPTP 557 Query: 400 STALG------ILAMKASCSSLPMGAAPDMTMRMDARSPAVTWGLLAISTTMGGTKGATV 239 S++ + + SS P+ P + + +P T + STT + A Sbjct: 558 SSSTTESSSTPVTSSTTESSSAPV-PTPSSSTTESSSAPVPT---PSSSTTESSSAPAPT 613 Query: 238 MPCARTSSTSAPMSNLRMITIADPARSPASST 143 + T S+SAP+++ + + P +P+SST Sbjct: 614 PSSSTTESSSAPVTSSTTESSSAPVPTPSSST 645 Score = 29.6 bits (65), Expect = 8.6 Identities = 35/152 (23%), Positives = 61/152 (40%), Gaps = 17/152 (11%) Frame = -2 Query: 547 APVSGSTILSPALRTTVPHDPDLTLNGSLANARHMASTGPASVIPYPCPSTALG------ 386 APV+ ST S + P T + S +ST +S P P PS++ Sbjct: 624 APVTSSTTESSSAPVPTPSS-STTESSSAPVPTPSSSTTESSSAPVPTPSSSTTESSSAP 682 Query: 385 ILAMKASCSSLPMGAA-----------PDMTMRMDARSPAVTWGLLAISTTMGGTKGATV 239 + + SS P+ ++ P + + +P T + STT + Sbjct: 683 VTSSTTESSSAPVTSSTTESSSAPVPTPSSSTTESSSAPVPT---PSSSTTESSSAPVPT 739 Query: 238 MPCARTSSTSAPMSNLRMITIADPARSPASST 143 + T S+SAP+++ + + P +P+SST Sbjct: 740 PSSSTTESSSAPVTSSTTESSSAPVPTPSSST 771
>ANGR_VIBAN (P19828) Protein angR| Length = 1048 Score = 34.3 bits (77), Expect = 0.35 Identities = 54/237 (22%), Positives = 99/237 (41%), Gaps = 15/237 (6%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPL---FHIYSLNSVLLAGLRAGS 173 KGV+++H+ + + N K D +L L L +Y + +L AG G+ Sbjct: 609 KGVVISHQGALNTCI----AINRRYQIGKNDRVLALSALHFDLSVYDIFGLLSAG---GT 661 Query: 174 AMVI--MRKFDIGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLA--SIRMVMSGA 341 +++ + + D A + + H +T+ VP + ++ + +A +R+ M Sbjct: 662 IVLVSELERRDPIAWCQAIEEHNVTMWNSVPALF-DMLLTYATCFNSIAPSKLRLTMLSG 720 Query: 342 APMGKELQDAFMA-KIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAG 518 +G +L + ++ + G G TEA + + K P + +S G + Sbjct: 721 DWIGLDLPQRYRNYRVDGQFIAMG-GATEAS-IWSNVFDVEKVPMEWRSIPYGYPLPRQQ 778 Query: 519 LKIVDPDTGASLGRNQP----GEICIRGEQIMKGYLNDPESTKNT---IDKDGWLHT 668 ++VD LGR+ P GE+ I G+ I GY +D T+ ID W T Sbjct: 779 YRVVD-----DLGRDCPDWVAGELWIGGDGIALGYFDDELKTQAQFLHIDGHAWYRT 830
>SRFAC_BACSU (Q08787) Surfactin synthetase subunit 3| Length = 1274 Score = 33.9 bits (76), Expect = 0.45 Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 4/79 (5%) Frame = +3 Query: 411 YGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGASLGRNQP----GEI 578 YG TE G V A P + S G + NA + I++ + + QP GE+ Sbjct: 753 YGPTE-GTVFATAHVVHDLPDSISSLPIGKPISNASVYILNEQS-----QLQPFGAVGEL 806 Query: 579 CIRGEQIMKGYLNDPESTK 635 CI G + KGY+N + TK Sbjct: 807 CISGMGVSKGYVNRADLTK 825
>S27A5_RAT (Q9ES38) Bile acyl-CoA synthetase (EC 6.2.1.7) (BACS) (Bile acid| CoA ligase) (BA-CoA ligase) (BAL) (Cholate--CoA ligase) (Very long chain acyl-CoA synthetase-related protein) (VLACS-related) (VLACSR) (Fatty acid transport protein 5) (FATP-5) (S Length = 690 Score = 33.5 bits (75), Expect = 0.59 Identities = 24/112 (21%), Positives = 48/112 (42%) Frame = +3 Query: 90 EDVLLCLLPLFHIYSLNSVLLAGLRAGSAMVIMRKFDIGALVELVRAHGITVAPFVPPIV 269 +DV+ +LPL+H L +L L+ G+ V+ KF R + +TV +V ++ Sbjct: 327 DDVVYNVLPLYHSMGLVLGVLGCLQLGATCVLAPKFSASRYWAECRQYSVTVVLYVGEVL 386 Query: 270 VEIAKSPQVTAGDLASIRMVMSGAAPMGKELQDAFMAKIPNAVLGQGYGMTE 425 + P ++R + + ++ + F + + + YG TE Sbjct: 387 RYLCNVPGQPEDKKHTVRFALGNG--LRADVWENFQQRFGPIQIWELYGSTE 436
>WNK1_MOUSE (P83741) Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein| kinase with no lysine 1) (Protein kinase, lysine-deficient 1) Length = 2377 Score = 33.1 bits (74), Expect = 0.78 Identities = 38/157 (24%), Positives = 72/157 (45%), Gaps = 11/157 (7%) Frame = -2 Query: 472 NGSLANARHMASTGPASVIPYPCPSTALGILAMKASCSSLPMGAAP-----DMTMRMDAR 308 N + N HMA GP + P+ + +A S+P+ ++P M+ + Sbjct: 1315 NTAPPNFNHMA--GP-TFSPFLASIAGVQTVAASTPSVSVPITSSPLNDISTSVMQSETA 1371 Query: 307 SPAVTWGLLAISTTMGG---TKGATVMPCARTSSTSAPMSNLRM---ITIADPARSPASS 146 P G++ ++TT G + G T M + + ++S+ +S+ + +T++ P++ +S Sbjct: 1372 LPTEK-GIVGVTTTSTGVVASGGLTTMSVSESPTSSSAVSSSTVPAVVTVSTPSQPVQAS 1430 Query: 145 TELSE*MWNSGSRHSSTSSFLKYRFGFSPSTCCATLV 35 T SGS SST SF F + +T ++V Sbjct: 1431 T--------SGSIASSTGSFPPGTFSTTTATTMGSVV 1459
>FAD33_MYCTU (P0A4X8) Putative fatty-acid--CoA ligase fadD33 (EC 6.2.1.-)| (Acyl-CoA synthetase) Length = 521 Score = 33.1 bits (74), Expect = 0.78 Identities = 53/212 (25%), Positives = 83/212 (39%), Gaps = 20/212 (9%) Frame = +3 Query: 93 DVLLCLLPLFHIYSLNSVLLAGLRAGSAMVIMRKFDIGAL----VELVRAHG--ITVAP- 251 DV LPL+H L VL A L AG+ + + A + + G +T AP Sbjct: 194 DVGCSWLPLYHDMGLAFVLSAAL-AGAPLWLAPTTAFTASPFRWLSWLSDSGATMTAAPN 252 Query: 252 FVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKELQDAFMAKIPNAVLGQGYGMTEAG 431 F ++ + A+ +V+ DL ++R+ ++G P+ + F + G + G Sbjct: 253 FAYNLIGKYAR--RVSEVDLGALRVTLNGGEPVDCDGLTRFAEAMAPFGFDAGAVLPSYG 310 Query: 432 PVLAMCLAFAKEPF------KVKSGS-------CGTVVRNAGLKIVDPDTGASLGRNQPG 572 + C P +V GS G + ++I D A + G Sbjct: 311 LAESTCAVTVPVPGIGLLADRVIDGSGAHKHAVLGNPIPGMEVRISCGDQAAGNASREIG 370 Query: 573 EICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 EI IRG +M GYL + ID D W T Sbjct: 371 EIEIRGASMMAGYLG-----QQPIDPDDWFAT 397
>FAD33_MYCBO (P0A4X9) Putative fatty-acid--CoA ligase fadD33 (EC 6.2.1.-)| (Acyl-CoA synthetase) Length = 521 Score = 33.1 bits (74), Expect = 0.78 Identities = 53/212 (25%), Positives = 83/212 (39%), Gaps = 20/212 (9%) Frame = +3 Query: 93 DVLLCLLPLFHIYSLNSVLLAGLRAGSAMVIMRKFDIGAL----VELVRAHG--ITVAP- 251 DV LPL+H L VL A L AG+ + + A + + G +T AP Sbjct: 194 DVGCSWLPLYHDMGLAFVLSAAL-AGAPLWLAPTTAFTASPFRWLSWLSDSGATMTAAPN 252 Query: 252 FVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMGKELQDAFMAKIPNAVLGQGYGMTEAG 431 F ++ + A+ +V+ DL ++R+ ++G P+ + F + G + G Sbjct: 253 FAYNLIGKYAR--RVSEVDLGALRVTLNGGEPVDCDGLTRFAEAMAPFGFDAGAVLPSYG 310 Query: 432 PVLAMCLAFAKEPF------KVKSGS-------CGTVVRNAGLKIVDPDTGASLGRNQPG 572 + C P +V GS G + ++I D A + G Sbjct: 311 LAESTCAVTVPVPGIGLLADRVIDGSGAHKHAVLGNPIPGMEVRISCGDQAAGNASREIG 370 Query: 573 EICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 EI IRG +M GYL + ID D W T Sbjct: 371 EIEIRGASMMAGYLG-----QQPIDPDDWFAT 397
>S27A2_HUMAN (O14975) Very-long-chain acyl-CoA synthetase (EC 6.2.1.-) (VLCS)| (Very-long-chain-fatty-acid-CoA ligase) (VLACS) (THCA-CoA ligase) (Fatty-acid-coenzyme A ligase, very long-chain 1) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Fatty acid Length = 620 Score = 32.7 bits (73), Expect = 1.0 Identities = 16/70 (22%), Positives = 34/70 (48%) Frame = +3 Query: 84 RKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMVIMRKFDIGALVELVRAHGITVAPFVPP 263 + +DV+ LP +H +L + + AG+ + + KF + R + +TV ++ Sbjct: 255 KADDVIYITLPFYHSAALLIGIHGCIVAGATLALRTKFSASQFWDDCRKYNVTVIQYIGE 314 Query: 264 IVVEIAKSPQ 293 ++ + SPQ Sbjct: 315 LLRYLCNSPQ 324
>VGP3_EBVP3 (P68344) Envelope glycoprotein GP340 (Membrane antigen) (MA)| Length = 886 Score = 32.3 bits (72), Expect = 1.3 Identities = 32/154 (20%), Positives = 59/154 (38%), Gaps = 4/154 (2%) Frame = -2 Query: 544 PVSGSTILSPALRTTVPHDPDLTLNG----SLANARHMASTGPASVIPYPCPSTALGILA 377 P +T +PA+ T P+ TL S +T P + P P+ + L Sbjct: 516 PTPNATSPTPAVTTPTPNATSPTLGKTSPTSAVTTPTPNATSPTPAVTTPTPNATIPTLG 575 Query: 376 MKASCSSLPMGAAPDMTMRMDARSPAVTWGLLAISTTMGGTKGATVMPCARTSSTSAPMS 197 + S++ + + SP + T+GGT V+ ++TSA + Sbjct: 576 KTSPTSAVTTPTPNATSPTVGETSPQAN----TTNHTLGGTSSTPVVTSPPKNATSAVTT 631 Query: 196 NLRMITIADPARSPASSTELSE*MWNSGSRHSST 95 IT + + + +SE + S S +S++ Sbjct: 632 GQHNITSSSTSSMSLRPSSISETLSPSTSDNSTS 665
>VGP3_EBVA8 (P68343) Envelope glycoprotein GP340 (Membrane antigen) (MA)| Length = 886 Score = 32.3 bits (72), Expect = 1.3 Identities = 32/154 (20%), Positives = 59/154 (38%), Gaps = 4/154 (2%) Frame = -2 Query: 544 PVSGSTILSPALRTTVPHDPDLTLNG----SLANARHMASTGPASVIPYPCPSTALGILA 377 P +T +PA+ T P+ TL S +T P + P P+ + L Sbjct: 516 PTPNATSPTPAVTTPTPNATSPTLGKTSPTSAVTTPTPNATSPTPAVTTPTPNATIPTLG 575 Query: 376 MKASCSSLPMGAAPDMTMRMDARSPAVTWGLLAISTTMGGTKGATVMPCARTSSTSAPMS 197 + S++ + + SP + T+GGT V+ ++TSA + Sbjct: 576 KTSPTSAVTTPTPNATSPTVGETSPQAN----TTNHTLGGTSSTPVVTSPPKNATSAVTT 631 Query: 196 NLRMITIADPARSPASSTELSE*MWNSGSRHSST 95 IT + + + +SE + S S +S++ Sbjct: 632 GQHNITSSSTSSMSLRPSSISETLSPSTSDNSTS 665
>VID21_CRYNE (Q5KL22) Chromatin modification-related protein VID21| Length = 985 Score = 32.3 bits (72), Expect = 1.3 Identities = 34/143 (23%), Positives = 51/143 (35%), Gaps = 9/143 (6%) Frame = -2 Query: 547 APVSGSTILSPALRTTVP----HDPDLTLNGSLANARHMASTGPASVIPYPCPSTALGIL 380 AP G + P L + P PDL G+ GP+ + P P P+ + Sbjct: 780 APSMGGNLQPPQLGVSSPFAQSRTPDLPAEGA----------GPSGINPTPSPAMQAAAI 829 Query: 379 AMKASCSSLPMGAAPDMTMRMDARSPAVTWGLLAISTTMG---GTKGATVMPC--ARTSS 215 ++S MG AP + R P IS+ M G MP A+T Sbjct: 830 GAQSSPQIATMGRAPSNNVPPHLRVPNAGTSSPQISSPMALPQGIPNGAGMPVQGAQTQG 889 Query: 214 TSAPMSNLRMITIADPARSPASS 146 P + + T+ + A+S Sbjct: 890 IQIPAAMMNNATVQQLLATLAAS 912
>HR4_DROME (Q9W539) Hormone receptor 4 (dHR4)| Length = 1518 Score = 32.3 bits (72), Expect = 1.3 Identities = 49/181 (27%), Positives = 69/181 (38%), Gaps = 14/181 (7%) Frame = -2 Query: 541 VSGSTILSPALRTTVPHDPDLTLNGSLANARHMASTGPASVIPYPCPSTALGILAMKASC 362 ++ ++ SP L P P L +GS AS G + +P P Sbjct: 38 IADTSTSSPDL--LAPMSPKLCDSGSAG-----ASLGASLPLPLALP------------- 77 Query: 361 SSLPMGAAPDMTMRMD--ARSPAVTWGLLAISTTMGGTKGATVM------------PCAR 224 LPM M++ + A S AVT L A+ + T GA PC Sbjct: 78 --LPMALPLPMSLPLPLTAASSAVTVSLAAVVAAVAETGGAGAGGAGTAVTASGAGPCVS 135 Query: 223 TSSTSAPMSNLRMITIADPARSPASSTELSE*MWNSGSRHSSTSSFLKYRFGFSPSTCCA 44 TSST+A A + +S++ LS +S S SSTSS S +TC A Sbjct: 136 TSSTTA-------------AAATSSTSSLSSSSSSSSSTSSSTSSASPTAGASSTATCPA 182 Query: 43 T 41 + Sbjct: 183 S 183
>DLTA_STAAU (P68877) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 485 Score = 32.0 bits (71), Expect = 1.7 Identities = 24/100 (24%), Positives = 41/100 (41%) Frame = +3 Query: 369 AFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGA 548 A +++ P+A + YG TEA V + +E + + L + GA Sbjct: 272 ALVSRFPSATIYNTYGPTEA-TVAVTSIQITQE----------ILDQYPTLPVGVERLGA 320 Query: 549 SLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 L GE+ I G+ + GYL + + T + D + T Sbjct: 321 RLSTTDDGELVIEGQSVSLGYLKNDQKTAEVFNFDDGIRT 360
>DLTA_STAAR (Q6GIF6) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 485 Score = 32.0 bits (71), Expect = 1.7 Identities = 24/100 (24%), Positives = 41/100 (41%) Frame = +3 Query: 369 AFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGA 548 A +++ P+A + YG TEA V + +E + + L + GA Sbjct: 272 ALVSRFPSATIYNTYGPTEA-TVAVTSIQITQE----------ILDQYPTLPVGVERPGA 320 Query: 549 SLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 L GE+ I G+ + GYL + + T + D + T Sbjct: 321 RLSTTDEGELVIEGQSVSLGYLKNDQKTAEVFNFDDGIRT 360
>DLTA_STAAN (P99107) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 485 Score = 32.0 bits (71), Expect = 1.7 Identities = 24/100 (24%), Positives = 41/100 (41%) Frame = +3 Query: 369 AFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGA 548 A +++ P+A + YG TEA V + +E + + L + GA Sbjct: 272 ALVSRFPSATIYNTYGPTEA-TVAVTSIQITQE----------ILDQYPTLPVGVERLGA 320 Query: 549 SLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 L GE+ I G+ + GYL + + T + D + T Sbjct: 321 RLSTTDDGELVIEGQSVSLGYLKNDQKTAEVFNFDDGIRT 360
>DLTA_STAAM (P68876) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 485 Score = 32.0 bits (71), Expect = 1.7 Identities = 24/100 (24%), Positives = 41/100 (41%) Frame = +3 Query: 369 AFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGA 548 A +++ P+A + YG TEA V + +E + + L + GA Sbjct: 272 ALVSRFPSATIYNTYGPTEA-TVAVTSIQITQE----------ILDQYPTLPVGVERLGA 320 Query: 549 SLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 L GE+ I G+ + GYL + + T + D + T Sbjct: 321 RLSTTDDGELVIEGQSVSLGYLKNDQKTAEVFNFDDGIRT 360
>NCF1_BOVIN (O77774) Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH| oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) Length = 392 Score = 32.0 bits (71), Expect = 1.7 Identities = 15/51 (29%), Positives = 28/51 (54%) Frame = -1 Query: 227 AHQLHQRADVELAHDHHRRPGAQPRQQHRVERVDVEQRQQAQQHVLLPEVQ 75 AH +HQR+ L+ D +RR + QQ R +R + ++ + A + P+ + Sbjct: 309 AHSIHQRSRKRLSQDTYRRNSVRFMQQRRHQRPEPQRSRSALREQQQPKTE 359
>MOT3_YEAST (P54785) Transcriptional activator/repressor MOT3 (Modulator of| transcription protein 3) (Hypoxic gene repressor protein 7) Length = 490 Score = 31.6 bits (70), Expect = 2.3 Identities = 16/39 (41%), Positives = 22/39 (56%), Gaps = 3/39 (7%) Frame = -1 Query: 185 DHHRRPGAQPRQQHRVERVDVEQRQ---QAQQHVLLPEV 78 DHH + Q RQQH+ ++ +Q Q Q QQH +L V Sbjct: 4 DHHLQQQQQQRQQHQQQQHQQQQHQHQHQQQQHTILQNV 42
>ILVX_BACSU (Q04789) Acetolactate synthase (EC 2.2.1.6) (Acetohydroxy-acid| synthase) (ALS) Length = 571 Score = 31.6 bits (70), Expect = 2.3 Identities = 32/122 (26%), Positives = 52/122 (42%), Gaps = 10/122 (8%) Frame = +3 Query: 288 PQVTAGDLASIRMVMSGAAP-MGKELQDAFMA--------KIPNAVLGQGYGMTEAGPVL 440 PQ ++ + + V + AAP +G DA A K+P ++G G EA + Sbjct: 172 PQDVVNEVTNTKNVRAVAAPKLGPAADDAISAAIAKIQTAKLPVVLVGMKGGRPEAIKAV 231 Query: 441 AMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTG-ASLGRNQPGEICIRGEQIMKGYLN 617 L + PF + GT+ R+ + D G L RNQPG++ + ++ Sbjct: 232 RKLLKKVQLPFVETYQAAGTLSRD----LEDQYFGRIGLFRNQPGDLLLEQADVVLTIGY 287 Query: 618 DP 623 DP Sbjct: 288 DP 289
>VID21_NEUCR (Q7SBU6) Chromatin modification-related protein vid-21| Length = 2189 Score = 31.6 bits (70), Expect = 2.3 Identities = 20/56 (35%), Positives = 29/56 (51%), Gaps = 6/56 (10%) Frame = -1 Query: 230 RAHQLHQRADVELAHD------HHRRPGAQPRQQHRVERVDVEQRQQAQQHVLLPE 81 +AHQ Q+A ++ H R G Q +Q H+V++ Q QQAQQ V P+ Sbjct: 2100 QAHQ-PQQASQQVQHGLVGQQGQQNRQGQQGQQSHQVQQAQQPQVQQAQQPVATPQ 2154
>S27A2_MOUSE (O35488) Very-long-chain acyl-CoA synthetase (EC 6.2.1.-) (VLCS)| (Very-long-chain-fatty-acid-CoA ligase) (VLACS) (THCA-CoA ligase) (Fatty-acid-coenzyme A ligase, very long-chain 1) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Fatty acid Length = 620 Score = 31.6 bits (70), Expect = 2.3 Identities = 15/68 (22%), Positives = 33/68 (48%) Frame = +3 Query: 90 EDVLLCLLPLFHIYSLNSVLLAGLRAGSAMVIMRKFDIGALVELVRAHGITVAPFVPPIV 269 +DV+ +PL+H +L L + G+ + + KF + R + +TV ++ ++ Sbjct: 257 QDVIYTTMPLYHSAALMIGLHGCIVVGATLALRSKFSASQFWDDCRKYNVTVIQYIGELL 316 Query: 270 VEIAKSPQ 293 + +PQ Sbjct: 317 RYLCNTPQ 324
>DLTA_LACPL (Q88VM6) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 508 Score = 31.2 bits (69), Expect = 2.9 Identities = 27/124 (21%), Positives = 49/124 (39%), Gaps = 1/124 (0%) Frame = +3 Query: 288 PQVTAGDLASIRMVMSGAAPMGKELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKE 467 P+ A +L ++ + + + + P+A + YG TE + Sbjct: 254 PKFNAENLPTLTHFLFCGEELTHKTAATLKKRFPDARIFNTYGPTETCVAVTQIEITDAA 313 Query: 468 PFKVKSGSCGTVVRNAGLKIVDPDTGASLGRNQPGEICIRGEQIMKGYLNDPEST-KNTI 644 + G + + +VD + G ++ GE+ I G + KGYLN+ E T K Sbjct: 314 LAQYDRLPIGYAKADTRILVVD-ENGEAVPNGTEGELIIAGPSVSKGYLNNSEKTAKAFF 372 Query: 645 DKDG 656 + DG Sbjct: 373 ELDG 376
>PO121_MOUSE (Q8K3Z9) Nuclear envelope pore membrane protein POM 121 (Pore| membrane protein of 121 kDa) Length = 1200 Score = 31.2 bits (69), Expect = 2.9 Identities = 56/234 (23%), Positives = 92/234 (39%), Gaps = 35/234 (14%) Frame = -2 Query: 598 ICSPRMQISPGWFRPREAPVSG------------STILSPALRTTVPHDPDLTLNGSLAN 455 + +P +P P +P++G +T L A +++ D +G ++ Sbjct: 596 VAAPSPPKTPSLLAPLVSPLAGPLASTSSDSKPAATFLGLASASSITPLTDSKSSG-VSQ 654 Query: 454 ARHMASTGPASVI--PYPCPSTALGILAMKASCSSL----PMGAAPDMTMRMDARSPAVT 293 A ST PAS P P PS G+L+ AS SSL P A+P A + + Sbjct: 655 AEQSVST-PASTASSPTPKPSMLFGMLSPPASSSSLATPAPACASPMFKPIFPATPKSES 713 Query: 292 WGLLAISTTMGGTKGATVMP--CARTSSTSAPMSNLRMITIADPARSP---------ASS 146 L S++ T ++ P A T+ T P+ + A P +P A++ Sbjct: 714 DSPLPSSSSAATTASSSTAPPTAASTTPTFKPIFDKMEPFTAMPLSTPFSLKQTTATATT 773 Query: 145 TELSE*MWNSGSRHSST------SSFLKYRFGFSPSTCCATLVMRLRCVSMTPL 2 T S ++ +ST +S K FGF +T +T + S + L Sbjct: 774 TATSAPLFTGLGTATSTVASGTAASASKPVFGFGVTTAASTASSTMTSTSQSVL 827
>DLTA_STAAW (P68878) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 485 Score = 30.8 bits (68), Expect = 3.8 Identities = 24/100 (24%), Positives = 40/100 (40%) Frame = +3 Query: 369 AFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGA 548 A + + P+A + YG TEA V + +E + + L + GA Sbjct: 272 ALVNRFPSATIYNTYGPTEA-TVAVTSIQITQE----------ILDQYPTLPVGVERPGA 320 Query: 549 SLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 L GE+ I G+ + GYL + + T + D + T Sbjct: 321 RLSTTDEGELVIEGQSVSLGYLKNDQKTAEVFNFDDGIRT 360
>DLTA_STAAS (Q6GAZ4) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 485 Score = 30.8 bits (68), Expect = 3.8 Identities = 24/100 (24%), Positives = 40/100 (40%) Frame = +3 Query: 369 AFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGA 548 A + + P+A + YG TEA V + +E + + L + GA Sbjct: 272 ALVNRFPSATIYNTYGPTEA-TVAVTSIQITQE----------ILDQYPTLPVGVERPGA 320 Query: 549 SLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 L GE+ I G+ + GYL + + T + D + T Sbjct: 321 RLSTTDEGELVIEGQSVSLGYLKNDQKTAEVFNFDDGIRT 360
>DLTA_STAAC (Q5HHF2) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 485 Score = 30.8 bits (68), Expect = 3.8 Identities = 24/100 (24%), Positives = 40/100 (40%) Frame = +3 Query: 369 AFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGA 548 A + + P+A + YG TEA V + +E + + L + GA Sbjct: 272 ALVNRFPSATIYNTYGPTEA-TVAVTSIQITQE----------ILDQYPTLPVGVERPGA 320 Query: 549 SLGRNQPGEICIRGEQIMKGYLNDPESTKNTIDKDGWLHT 668 L GE+ I G+ + GYL + + T + D + T Sbjct: 321 RLSTTDEGELVIEGQSVSLGYLKNDQKTAEVFNFDDGIRT 360
>DHMH_PARVE (P23006) Methylamine dehydrogenase heavy chain precursor (EC| 1.4.99.3) (MADH) Length = 426 Score = 30.8 bits (68), Expect = 3.8 Identities = 25/87 (28%), Positives = 37/87 (42%), Gaps = 7/87 (8%) Frame = -2 Query: 391 LGILAMKASCSSLPMGAAPDMTMRMDARSPAVTWGLLAISTTMGGTKGATVMPCARTSST 212 L ++ +CS+L +GAA T + +PA T A T G +GA A + Sbjct: 12 LTLIGATLACSALALGAAQAQTEPAEPEAPAETAAADAAGQT-EGQRGAAEAAAALAAGE 70 Query: 211 S-------APMSNLRMITIADPARSPA 152 + AP + R + I DPA A Sbjct: 71 ADEPVILEAPAPDARRVYIQDPAHFAA 97
>ATG15_ASPFU (Q4X180) Putative lipase atg15 (EC 3.1.1.3) (Autophagy-related| protein 15) Length = 650 Score = 30.8 bits (68), Expect = 3.8 Identities = 19/60 (31%), Positives = 28/60 (46%), Gaps = 2/60 (3%) Frame = -2 Query: 571 PGWFRPREAPVSGSTILSPALRTTVPHDPDLTLN--GSLANARHMASTGPASVIPYPCPS 398 PGWF R+ P + ++I S T+ DP A H ++GP++ PY PS Sbjct: 567 PGWFGCRDPPSTTASITSSPSTTSTCDDPGFFWGCYDESTTATHPITSGPSA--PYSTPS 624
>HWP1_CANAL (P46593) Hyphal wall protein 1 (Cell elongation protein 2)| Length = 634 Score = 30.8 bits (68), Expect = 3.8 Identities = 32/149 (21%), Positives = 65/149 (43%), Gaps = 8/149 (5%) Frame = -2 Query: 556 PREAPVSGSTILSPALRTTVPHDPDLTLNGSLANARHMASTGPASVIPYPCPSTALGILA 377 P + +T PA TT + + S + AST P S +P P+T++ + Sbjct: 189 PEKPTTPATTPNIPATTTTSESSSSSSSSSSSTTPKTSASTTPESSVPATTPNTSVPTTS 248 Query: 376 MKASC------SSLPM--GAAPDMTMRMDARSPAVTWGLLAISTTMGGTKGATVMPCART 221 +++ SS+P+ G++ T + +PA T ++ TT TK ++ T Sbjct: 249 SESTTPATSPESSVPVTSGSSILATTSESSSAPATTPN-TSVPTTTTETKSSS------T 301 Query: 220 SSTSAPMSNLRMITIADPARSPASSTELS 134 T+ + ++T+ + S + +E++ Sbjct: 302 PLTTTTEHDTTVVTVTSCSNSVCTESEVT 330
>DLTA_LACLA (Q9CG49) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 499 Score = 30.8 bits (68), Expect = 3.8 Identities = 47/228 (20%), Positives = 80/228 (35%), Gaps = 6/228 (2%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPLFHIYSLNSVLLAGLRAGSAMV 182 KGV ++H +L+T N + +L L F + + L L G ++ Sbjct: 160 KGVEVSHDNLVTFTNWM---NNDFMKIENNQILSQALYSFDLSIFS--LYPSLTTGGTLI 214 Query: 183 IMRKFD---IGALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAAPMG 353 + + + L E + I P V P T + + + + Sbjct: 215 SLSRDETTNFKLLFERLNKTVINTWISTPSFVDICLLDPSFTEKEHPQLVQFILCGEELT 274 Query: 354 KELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVD 533 K+ + + P+A + YG TEA ++ + + G LKI+D Sbjct: 275 KKTAEKLLTAFPSANIYNTYGPTEATGAISSVKITKELLTENDRVPIGFAKPGVDLKIMD 334 Query: 534 PDTGASLGRNQPGEICIRGEQIMKGYLNDPESTKN---TIDKDGWLHT 668 EI I G+ + KGY +PE T+ T+D HT Sbjct: 335 K------------EIIIVGDSVAKGYFENPEKTEQAFFTVDGKPAYHT 370
>AP180_HUMAN (O60641) Clathrin coat assembly protein AP180 (Clathrin| coat-associated protein AP180) (91 kDa synaptosomal-associated protein) Length = 907 Score = 30.4 bits (67), Expect = 5.0 Identities = 32/121 (26%), Positives = 45/121 (37%), Gaps = 3/121 (2%) Frame = -2 Query: 556 PREAPVSGSTILSPALRTTVPHDPDLTLNGSLANARHMASTGPASVIPYPCPSTALGILA 377 P EAP + +PA T V L+ N S G A P L + A Sbjct: 448 PGEAPAASEGAAAPATPTPVA----AALDACSGNDPFAPSEGSAEAAP------ELDLFA 497 Query: 376 MKASCSSLPMGAAPDMT---MRMDARSPAVTWGLLAISTTMGGTKGATVMPCARTSSTSA 206 MK +S+P+ T + A SPA A +TT T + ++T+A Sbjct: 498 MKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTA 557 Query: 205 P 203 P Sbjct: 558 P 558
>TARA_HUMAN (Q9H2D6) TRIO and F-actin-binding protein (Protein Tara)| (Trio-associated repeat on actin) Length = 2365 Score = 30.4 bits (67), Expect = 5.0 Identities = 48/192 (25%), Positives = 73/192 (38%), Gaps = 34/192 (17%) Frame = -2 Query: 559 RPREAPVSGSTILSPALRTTVP----------------------HDPDLTLNGSLANARH 446 RPRE P + S+ +P+L T P H L L+ RH Sbjct: 177 RPREGPRADSSQRAPSLLTRSPVGGDAAGQKKEDTGGGGRSAGQHWARLRGESGLSLERH 236 Query: 445 MAS-TGPASVIPYPCP-------STALGILAMKASCSSLPMGAAPD-MTMRMDARSPAVT 293 ++ T +S+ P+ P S A A AS +P ++P +T R +R+ + Sbjct: 237 RSTLTQASSMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPHRITQRDTSRASSTQ 296 Query: 292 WGLLAISTTMGGTKGA--TVMPCARTSSTSAPMSNLRMITIADP-ARSPASSTELSE*MW 122 + S+T T A T R SST P A SP+ ST+L Sbjct: 297 QEISRASSTQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQLDNPRT 356 Query: 121 NSGSRHSSTSSF 86 +S + + +SF Sbjct: 357 SSTQQDNPQTSF 368
>DHBF_BACSU (P45745) Dimodular nonribosomal peptide synthetase| Length = 2378 Score = 30.4 bits (67), Expect = 5.0 Identities = 57/223 (25%), Positives = 94/223 (42%), Gaps = 13/223 (5%) Frame = +3 Query: 3 KGVMLTHRSLITSVAQQVDGENPNLYFRKEDVLLCLLPL-FHIYSLNSVLLAGLRAGSAM 179 KGV++T +SL + + + +ED LL + + F I +L L L +G+ + Sbjct: 620 KGVVVTQKSLSNFLLSMQEAFS----LGEEDRLLAVTTVAFDISALE--LYLPLISGAQI 673 Query: 180 VIMRKFDIG---ALVELVRAHGITVAPFVPPIVVEIAKSPQVTAGDLASIRMVMSGAA-P 347 VI +K I AL +++ I + P + + S L +R+++ G A P Sbjct: 674 VIAKKETIREPQALAQMIENFDINIMQATPTLWHALVTSEPEK---LRGLRVLVGGEALP 730 Query: 348 MG--KELQDAFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKE------PFKVKSGSCGTV 503 G +ELQD + + N YG TE + AF +E P + Sbjct: 731 SGLLQELQDLHCS-VTNL-----YGPTET--TIWSAAAFLEEGLKGVPPIGKPIWNTQVY 782 Query: 504 VRNAGLKIVDPDTGASLGRNQPGEICIRGEQIMKGYLNDPEST 632 V + GL+ V P GE+ I G + +GY + P+ T Sbjct: 783 VLDNGLQPVPPGV--------VGELYIAGTGLARGYFHRPDLT 817
>YRHG_BACSU (O05399) Hypothetical transport protein yrhG| Length = 266 Score = 30.4 bits (67), Expect = 5.0 Identities = 30/132 (22%), Positives = 55/132 (41%), Gaps = 14/132 (10%) Frame = +3 Query: 135 LNSVLLAGLRAGSAMVIMRKFDIGALVELVRAHG-----ITVAPFVPPIVVEIAKSPQVT 299 L S+L+ G G+ + + DI + +L + G I A F +++ + ++ Sbjct: 25 LPSLLVLGFLGGAFIALGYLLDIRVIGDLPKEWGSLSSLIGAAVFPVGLILVVLAGAELI 84 Query: 300 AGDLASIRMVMSGAAPMGKELQDAF-MAKIPNAV--------LGQGYGMTEAGPVLAMCL 452 G++ S+ M + KEL + + I N + G G+TE GP L + Sbjct: 85 TGNMMSVAMALFSRKISVKELAINWGIVTIMNLIGALFVAYFFGHLVGLTETGPYLEKTI 144 Query: 453 AFAKEPFKVKSG 488 A A+ + G Sbjct: 145 AVAQGKLDMSFG 156
>FOXC1_HUMAN (Q12948) Forkhead box protein C1 (Forkhead-related protein FKHL7)| (Forkhead-related transcription factor 3) (FREAC-3) Length = 553 Score = 30.4 bits (67), Expect = 5.0 Identities = 32/132 (24%), Positives = 51/132 (38%), Gaps = 15/132 (11%) Frame = -2 Query: 556 PREAPVSGSTILSPALRTTVPHDPDLTLN----GSLANARHMASTGPASVIPYPCPST-- 395 P A SGS P + + L+ GSL +AR ++ G S P P PS Sbjct: 242 PAAALGSGSAAAVPKIESPDSSSSSLSSGSSPPGSLPSARPLSLDGADSAPPPPAPSAPP 301 Query: 394 -----ALGILAMKASCSSLPMGAAPDMTMRMDARSPAVTWGLLAISTTMG----GTKGAT 242 + + S P AA +++ + A + A + +A +G G Sbjct: 302 PHHSQGFSVDNIMTSLRGSPQSAAAELSSGLLASAAASSRAGIAPPLALGAYSPGQSSLY 361 Query: 241 VMPCARTSSTSA 206 PC++TSS + Sbjct: 362 SSPCSQTSSAGS 373
>COHA1_CANFA (Q9N281) Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen| 2) (180 kDa bullous pemphigoid antigen 2) (Fragment) Length = 709 Score = 30.0 bits (66), Expect = 6.6 Identities = 29/111 (26%), Positives = 48/111 (43%), Gaps = 4/111 (3%) Frame = -2 Query: 520 SPALRTTVPHDPDLTLNGSLANARHMASTGPA---SVIPYPCPSTALGILAMKASCSSLP 350 SPA +T+P+ P T G + RH G + S YP A +S Sbjct: 85 SPA--STLPNSPGSTFEGKIHITRHGTYEGSSSGNSSPEYPRKEFA------SSSTRGRS 136 Query: 349 MGAAPDMTMRMDARSPAVTWGLL-AISTTMGGTKGATVMPCARTSSTSAPM 200 ++ +R+ + SP+ W L + + G++ A+V P R SS + P+ Sbjct: 137 QTRESEIRVRLQSASPSTRWTELDDVKRLLKGSRSASVSP-TRDSSNTLPI 186
>EP400_MOUSE (Q8CHI8) E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa| SWI2/SNF2-related protein) (Domino homolog) (mDomino) Length = 3072 Score = 30.0 bits (66), Expect = 6.6 Identities = 27/97 (27%), Positives = 46/97 (47%), Gaps = 2/97 (2%) Frame = -2 Query: 418 IPYPCPSTALGILAMKASCSSLPMGAAPDMTMRMDARSPAVTWGLLAISTTMGGTKGA-- 245 IP P PS + SS P A P + + M ++ T L + + T+ T+ Sbjct: 637 IPAPLPSQL-------PAPSSQP--AQPALHVPMPGKAQMQTSQLSSQTQTVASTRPPLD 687 Query: 244 TVMPCARTSSTSAPMSNLRMITIADPARSPASSTELS 134 + PC R+ TS+ S+L ++ + P SPA S+ ++ Sbjct: 688 SAQPCQRSLPTSSSSSSLVPVSGSGPGPSPARSSPVN 724
>KCNH2_RABIT (Q8WNY2) Potassium voltage-gated channel subfamily H member 2| (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (RERG) (ra-erg) (Ether-a-go-go-related protein 1) (Eag-related protein 1) Length = 1161 Score = 30.0 bits (66), Expect = 6.6 Identities = 45/193 (23%), Positives = 72/193 (37%), Gaps = 2/193 (1%) Frame = -2 Query: 577 ISPGWFRPREAPVSGSTILSPALRTTVPHDPDLTLNGSLANARHMASTGPASVIPYPCPS 398 + PG AP G+ ++ L P L L+ A H+A GPA Sbjct: 180 VRPGGAGGAGAP--GAVVVDVDLTPAAPSSESLALDEVPAMDNHVAGLGPAE-------- 229 Query: 397 TALGILAMKASCSSLPMGAA--PDMTMRMDARSPAVTWGLLAISTTMGGTKGATVMPCAR 224 A+ SCS P +A P ++R + +P + +++ T A+V R Sbjct: 230 ---ERRALVGSCSPPPPVSAPGPHPSLRAHSLNPDASGSSCSLARTRSRESCASV----R 282 Query: 223 TSSTSAPMSNLRMITIADPARSPASSTELSE*MWNSGSRHSSTSSFLKYRFGFSPSTCCA 44 +S++ + +R + P RH+ST + R G ST + Sbjct: 283 RASSADDIEAMRAGALPPP------------------PRHASTGAMHPLRSGLLNSTSDS 324 Query: 43 TLVMRLRCVSMTP 5 LV R R +S P Sbjct: 325 DLV-RYRTISKIP 336
>BMP2K_HUMAN (Q9NSY1) BMP-2-inducible protein kinase (EC 2.7.11.1) (BIKe)| Length = 1161 Score = 30.0 bits (66), Expect = 6.6 Identities = 15/45 (33%), Positives = 25/45 (55%) Frame = -1 Query: 230 RAHQLHQRADVELAHDHHRRPGAQPRQQHRVERVDVEQRQQAQQH 96 R QLH ++ H H ++ Q +QQ + ++ +Q+QQ QQH Sbjct: 447 RLQQLH----LQHRHPHQQQQQQQQQQQQQQQQQQQQQQQQQQQH 487
>PQE1_CAEEL (Q10124) Putative RNA exonuclease pqe-1 (PolyQ enhancer protein 1)| Length = 1647 Score = 30.0 bits (66), Expect = 6.6 Identities = 21/66 (31%), Positives = 27/66 (40%) Frame = -2 Query: 496 PHDPDLTLNGSLANARHMASTGPASVIPYPCPSTALGILAMKASCSSLPMGAAPDMTMRM 317 P + L N N + + P V P+ P ALG P GAAP MT + Sbjct: 281 PANAQLAQNAQQRNPQQVPM--PQGVAPHHIPPQALG-----------PHGAAPQMTQQA 327 Query: 316 DARSPA 299 AR P+ Sbjct: 328 PARGPS 333
>FOXK1_MOUSE (P42128) Forkhead box protein K1 (Myocyte nuclear factor) (MNF)| Length = 617 Score = 30.0 bits (66), Expect = 6.6 Identities = 35/155 (22%), Positives = 60/155 (38%), Gaps = 12/155 (7%) Frame = -2 Query: 592 SPRMQISPGWFRPREAPVSGSTILSPALRTTVPHDPDLTLNGSLANARHMASTGPAS--- 422 SP PG PR + + LS + +PHDPDL + + + P S Sbjct: 401 SPASPTHPGLMSPRSSGLQTPECLSRE-GSPIPHDPDLGSKLASVPEYRYSQSAPGSPVS 459 Query: 421 -------VIPYPCPSTALGILAMKAS--CSSLPMGAAPDMTMRMDARSPAVTWGLLAIST 269 V P P A + M AS S P G A + + ++P VT ++ + T Sbjct: 460 AQPVIMAVPPRPSNLVAKPVAYMPASIVTSQQPSGHA----IHVVQQAPTVT--MVRVVT 513 Query: 268 TMGGTKGATVMPCARTSSTSAPMSNLRMITIADPA 164 T + ++ ++ TS + ++ + + A Sbjct: 514 TSANSANGYILASQGSTGTSHDTAGTAVLDLGNEA 548
>MSH7_ARATH (Q9SMV7) DNA mismatch repair protein MSH6-2 (AtMsh6-2) (MutS homolog| 7) Length = 1109 Score = 29.6 bits (65), Expect = 8.6 Identities = 27/92 (29%), Positives = 36/92 (39%), Gaps = 19/92 (20%) Frame = +3 Query: 210 LVELVRAHGITVAPFVPPIVVEIAKSPQVTA-------------------GDLASIRMVM 332 LVE V+ + A P+ E A P+VT+ DL + + Sbjct: 954 LVEKVQCR-MLFATHYHPLTKEFASHPRVTSKHMACAFKSRSDYQPRGCDQDLVFLYRLT 1012 Query: 333 SGAAPMGKELQDAFMAKIPNAVLGQGYGMTEA 428 GA P LQ A MA IPN V+ G +A Sbjct: 1013 EGACPESYGLQVALMAGIPNQVVETASGAAQA 1044
>ACKA_NOCFA (Q5YNP4) Acetate kinase (EC 2.7.2.1) (Acetokinase)| Length = 402 Score = 29.6 bits (65), Expect = 8.6 Identities = 15/36 (41%), Positives = 20/36 (55%), Gaps = 1/36 (2%) Frame = -1 Query: 569 GLVPAEGGA-GVGVDDLEPGVAHHRAARPGLDLERL 465 GL P EG G DL+PG+ H A G D++R+ Sbjct: 232 GLTPLEGLVMGTRGGDLDPGILGHLARAAGFDVDRI 267
>SOX30_MOUSE (Q8CGW4) Transcription factor SOX-30| Length = 782 Score = 29.6 bits (65), Expect = 8.6 Identities = 44/179 (24%), Positives = 70/179 (39%), Gaps = 8/179 (4%) Frame = -2 Query: 571 PGW-FRPREAPVSGSTILSPALRTTVPHDPDLTLNGSLANARHMASTGPASVIPYPCPST 395 PGW ++PR P R P +G+ N + ST P ++ PY P+ Sbjct: 431 PGWVYQPR-----------PGKRKRFPLSVSNVFSGTTQN---IISTNPTTIYPYRSPTY 476 Query: 394 ALGILAMKASCSSLPMGAAPDMTMRMDARSPAV--TWGLLAISTTMGGTKGATVMPCART 221 ++ I ++ + + P+G AP + +PAV + ++ T V P + T Sbjct: 477 SVVIPGLQNTITH-PVGEAPP---AIQLPTPAVQRPSPITLFQPSVSSTGPVAVPPPSLT 532 Query: 220 SSTSAPMSNLRMITIADPARSPASSTELSE*MWNSGSRHSST-----SSFLKYRFGFSP 59 S P + D R P+ S+ S GS S+T +S RF SP Sbjct: 533 PRPSLPPQRFSGPSQTDIHRLPSGSSR-SVKRSTPGSLESTTRIPAGASTAHARFATSP 590
>DLTA_STAES (Q8CT93) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 485 Score = 29.6 bits (65), Expect = 8.6 Identities = 23/88 (26%), Positives = 36/88 (40%) Frame = +3 Query: 369 AFMAKIPNAVLGQGYGMTEAGPVLAMCLAFAKEPFKVKSGSCGTVVRNAGLKIVDPDTGA 548 A + + PN+++ YG TEA V + +E + V R G Sbjct: 272 ALVERFPNSMIYNTYGPTEA-TVAVTSIQITEEILNQYNPLPVGVAR----------PGT 320 Query: 549 SLGRNQPGEICIRGEQIMKGYLNDPEST 632 L + GE+ I G+ + GYL + E T Sbjct: 321 KLFATEEGELVIEGQSVSLGYLKNEEKT 348
>CYLN2_HUMAN (Q9UDT6) Cytoplasmic linker protein 2 (Cytoplasmic linker protein| 115) (CLIP-115) (Williams-Beuren syndrome chromosome region 4 protein) Length = 1046 Score = 29.6 bits (65), Expect = 8.6 Identities = 19/55 (34%), Positives = 26/55 (47%), Gaps = 8/55 (14%) Frame = -1 Query: 221 QLHQRADVELAHDHHRRPGAQPRQQ--------HRVERVDVEQRQQAQQHVLLPE 81 Q H RA +E+ HR + + Q H +E++DVE R QAQ L E Sbjct: 700 QRHWRAQLEVQASQHRLELQEAQDQRRDAELRVHELEKLDVEYRGQAQAIEFLKE 754
>ODD_DROME (P23803) Protein odd-skipped| Length = 392 Score = 29.6 bits (65), Expect = 8.6 Identities = 19/61 (31%), Positives = 30/61 (49%), Gaps = 3/61 (4%) Frame = -1 Query: 227 AHQLHQRADVELAHDHHRRPGAQPRQQHRV---ERVDVEQRQQAQQHVLLPEVQVRVLSV 57 A QLH R +AH ++ Q +QQHR+ + +Q Q QQ+ + P ++V Sbjct: 70 ATQLHMR---HMAHYQQQQQQQQQQQQHRLWLQMQQQQQQHQAPQQYPVYPTASADPVAV 126 Query: 56 H 54 H Sbjct: 127 H 127
>POLG_PEV9U (O41174) Genome polyprotein [Contains: Coat protein VP4 (P1A); Coat| protein VP2 (P1B); Coat protein VP3 (P1C); Coat protein VP1 (P1D); Picornain 2A (EC 3.4.22.29) (Core protein P2A); Core protein P2B; Core protein P2C; Core protein P3A; Genome Length = 2167 Score = 29.6 bits (65), Expect = 8.6 Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 2/73 (2%) Frame = -2 Query: 421 VIPYPCPSTA--LGILAMKASCSSLPMGAAPDMTMRMDARSPAVTWGLLAISTTMGGTKG 248 VIP PSTA L LA + + S + PD+T ++P T AIS+ + G Sbjct: 513 VIPPDFPSTAYILCFLAAQPNFSLRILKDRPDITQTAALQAPVETALNSAISSVIAGITA 572 Query: 247 ATVMPCARTSSTS 209 P + STS Sbjct: 573 QDTQPSSHNISTS 585 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 72,447,272 Number of Sequences: 219361 Number of extensions: 1418751 Number of successful extensions: 6541 Number of sequences better than 10.0: 202 Number of HSP's better than 10.0 without gapping: 5888 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6360 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 6484657212 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
