>NCX6_CAEEL (P34315) Putative sodium/calcium exchanger 6 precursor|
           (Na(+)/Ca(2+)-exchange protein 6)
          Length = 590

 Score = 38.1 bits (87), Expect = 0.019
 Identities = 21/87 (24%), Positives = 42/87 (48%), Gaps = 3/87 (3%)
 Frame = +1

Query: 130 VRDVGFFLITLVALSIMLI-VGKVTVWGAMLFVSIYVVYAFVVAANELLRKHARM--LKF 300
           +RD+ F+L+ L  L+   +    V +W  + F+ +Y++Y   V  +++L    +    K 
Sbjct: 205 IRDIAFYLVALAFLAFCFVYYDHVEIWMPITFLGVYLIYVCTVILSQILHNRHKKDEEKV 264

Query: 301 DVVTPLLPVRGSIFAQGIEEDDSVYSS 381
           D V        ++    +E+DD +Y S
Sbjct: 265 DEVK-------TVDTDSLEDDDDIYVS 284

>NCKX6_HUMAN (Q6J4K2) Sodium/potassium/calcium exchanger 6 precursor|
           (Na(+)/K(+)/Ca(2+)-exchange protein 6) (Solute carrier
           family 24 member 6)
          Length = 584

 Score = 37.4 bits (85), Expect = 0.033
 Identities = 27/96 (28%), Positives = 47/96 (48%)
 Frame = +1

Query: 121 RCFVRDVGFFLITLVALSIMLIVGKVTVWGAMLFVSIYVVYAFVVAANELLRKHARMLKF 300
           R F RD+ F+++ +    +ML  G+VT+  A+ ++ +YV Y   V     +  + R  + 
Sbjct: 200 RPFFRDIVFYMVAVFLTFLMLFRGRVTLAWALGYLGLYVFYVVTVILCTWI--YQRQRRG 257

Query: 301 DVVTPLLPVRGSIFAQGIEEDDSVYSSLLEEDTSDE 408
            +  P +PV   I +    E+D V S+    D  DE
Sbjct: 258 SLFCP-MPVTPEILSD--SEEDRVSSNTNSYDYGDE 290

>NCKX3_RAT (Q9EPQ0) Sodium/potassium/calcium exchanger 3 precursor|
           (Na(+)/K(+)/Ca(2+)-exchange protein 3) (Fragment)
          Length = 624

 Score = 36.6 bits (83), Expect = 0.056
 Identities = 19/89 (21%), Positives = 41/89 (46%)
 Frame = +1

Query: 13  GDVGLNSXXXXXXXXXXXXXXXXSLSVAEKNVQIDWRCFVRDVGFFLITLVALSIMLIVG 192
           GDVG+ +                 L   +      W C +RD  ++ +++VAL + +   
Sbjct: 157 GDVGVGTIVGSAVFNILCIIGVCGLFAGQVVALSSW-CLLRDSIYYTLSVVALIVFIYDE 215

Query: 193 KVTVWGAMLFVSIYVVYAFVVAANELLRK 279
           KV+ W +++ V +Y++Y  ++  N  + +
Sbjct: 216 KVSWWESLVLVLMYLIYIIIMKYNACIHQ 244

>NCKX3_MOUSE (Q99PD7) Sodium/potassium/calcium exchanger 3 precursor|
           (Na(+)/K(+)/Ca(2+)-exchange protein 3)
          Length = 645

 Score = 36.2 bits (82), Expect = 0.073
 Identities = 19/89 (21%), Positives = 41/89 (46%)
 Frame = +1

Query: 13  GDVGLNSXXXXXXXXXXXXXXXXSLSVAEKNVQIDWRCFVRDVGFFLITLVALSIMLIVG 192
           GDVG+ +                 L   +      W C +RD  ++ +++VAL + +   
Sbjct: 175 GDVGVGTIVGSAVFNILCIIGVCGLFAGQVVALSSW-CLLRDSIYYTLSVVALIVFIYDE 233

Query: 193 KVTVWGAMLFVSIYVVYAFVVAANELLRK 279
           KV+ W +++ V +Y++Y  ++  N  + +
Sbjct: 234 KVSWWESLVLVLMYLIYIVIMKYNACIHQ 262

>NCKX1_CHICK (Q9IAL8) Sodium/potassium/calcium exchanger 1 precursor|
           (Na(+)/K(+)/Ca(2+)-exchange protein 1) (Retinal rod
           Na-Ca+K exchanger)
          Length = 663

 Score = 35.0 bits (79), Expect = 0.16
 Identities = 13/58 (22%), Positives = 29/58 (50%)
 Frame = +1

Query: 106 VQIDWRCFVRDVGFFLITLVALSIMLIVGKVTVWGAMLFVSIYVVYAFVVAANELLRK 279
           + + W    RD+ F+++ L+ L +  +   +  W ++L ++ Y  Y F +  N  L +
Sbjct: 227 LHLTWWPLFRDISFYIVDLLMLILFFLDSVIDWWESLLLLTAYATYVFTMKHNVSLEQ 284

>NCKX1_HUMAN (O60721) Sodium/potassium/calcium exchanger 1|
           (Na(+)/K(+)/Ca(2+)-exchange protein 1) (Retinal rod
           Na-Ca+K exchanger)
          Length = 1099

 Score = 34.3 bits (77), Expect = 0.28
 Identities = 13/54 (24%), Positives = 27/54 (50%)
 Frame = +1

Query: 106 VQIDWRCFVRDVGFFLITLVALSIMLIVGKVTVWGAMLFVSIYVVYAFVVAANE 267
           + + W    RDV F+++ L+ L +  +   +  W ++L +  Y  Y F +  N+
Sbjct: 551 LNLTWWPLFRDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYVFTMKWNK 604

>NCKX2_HUMAN (Q9UI40) Sodium/potassium/calcium exchanger 2 precursor|
           (Na(+)/K(+)/Ca(2+)-exchange protein 2) (Retinal cone
           Na-Ca+K exchanger) (Solute carrier family 24 member 2)
          Length = 661

 Score = 34.3 bits (77), Expect = 0.28
 Identities = 14/63 (22%), Positives = 30/63 (47%)
 Frame = +1

Query: 106 VQIDWRCFVRDVGFFLITLVALSIMLIVGKVTVWGAMLFVSIYVVYAFVVAANELLRKHA 285
           + + W    RDV F+++ L+ L I  +   +  W ++L ++ Y  Y   +  N  + K  
Sbjct: 231 LNLTWWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFCYVVFMKFNVQVEKWV 290

Query: 286 RML 294
           + +
Sbjct: 291 KQM 293

>NCKX1_RAT (Q9QZM6) Sodium/potassium/calcium exchanger 1|
           (Na(+)/K(+)/Ca(2+)-exchange protein 1) (Retinal rod
           Na-Ca+K exchanger)
          Length = 1181

 Score = 34.3 bits (77), Expect = 0.28
 Identities = 13/58 (22%), Positives = 29/58 (50%)
 Frame = +1

Query: 106 VQIDWRCFVRDVGFFLITLVALSIMLIVGKVTVWGAMLFVSIYVVYAFVVAANELLRK 279
           + + W    RDV F+++ L  L +  +   +  W ++L +  Y +Y F +  N+ + +
Sbjct: 518 LNLTWWPLFRDVSFYILDLSMLIVFFLDSLIAWWESLLLLLAYALYVFTMKWNKQIER 575

>NCKX6_MOUSE (Q925Q3) Sodium/potassium/calcium exchanger 6 precursor|
           (Na(+)/K(+)/Ca(2+)-exchange protein 6) (Solute carrier
           family 24 member 6)
          Length = 585

 Score = 33.9 bits (76), Expect = 0.36
 Identities = 13/45 (28%), Positives = 27/45 (60%)
 Frame = +1

Query: 121 RCFVRDVGFFLITLVALSIMLIVGKVTVWGAMLFVSIYVVYAFVV 255
           R F+RD+ F+++ +      L +G++T+  A+ ++ +YV Y   V
Sbjct: 200 RPFLRDIAFYMVAVFLTFTALYLGRITLTWALGYLGLYVFYVVTV 244

>NCKX2_RAT (O54701) Sodium/potassium/calcium exchanger 2 precursor|
           (Na(+)/K(+)/Ca(2+)-exchange protein 2) (Retinal cone
           Na-Ca+K exchanger)
          Length = 670

 Score = 33.5 bits (75), Expect = 0.47
 Identities = 13/63 (20%), Positives = 30/63 (47%)
 Frame = +1

Query: 106 VQIDWRCFVRDVGFFLITLVALSIMLIVGKVTVWGAMLFVSIYVVYAFVVAANELLRKHA 285
           + + W    RDV F+++ L+ L I  +   +  W ++L ++ Y  Y   +  N  + +  
Sbjct: 232 LNLTWWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFAYVVFMKFNVQVERWV 291

Query: 286 RML 294
           + +
Sbjct: 292 KQM 294

>CYA1_DROME (P32870) Ca(2+)/calmodulin-responsive adenylate cyclase (EC 4.6.1.1)|
            (ATP pyrophosphate-lyase) (Protein rutabaga)
          Length = 2248

 Score = 33.1 bits (74), Expect = 0.62
 Identities = 19/59 (32%), Positives = 28/59 (47%)
 Frame = -3

Query: 412  PPHHLYPPQEVNCKQNHPPLFLVRRYFPSQEAMV*LHQTSASVRASLIAHLQQPQMHKP 236
            PPHHL+    +N  Q HPP F    Y   +E+   LH +S +  A ++     P+   P
Sbjct: 1431 PPHHLHSNLNLNQSQ-HPPSFTSLGYGQCRESEPLLHASSVAPVAKIMPMQHAPKYEPP 1488

>NCKX6_RAT (Q6AXS0) Sodium/potassium/calcium exchanger 6 precursor|
           (Na(+)/K(+)/Ca(2+)-exchange protein 6) (Solute carrier
           family 24 member 6)
          Length = 585

 Score = 32.7 bits (73), Expect = 0.81
 Identities = 13/45 (28%), Positives = 27/45 (60%)
 Frame = +1

Query: 121 RCFVRDVGFFLITLVALSIMLIVGKVTVWGAMLFVSIYVVYAFVV 255
           R F+RD+ F+++ +      L +G++T+  A+ ++ +YV Y   V
Sbjct: 200 RPFLRDITFYMVAVFLTFTALYLGRITLVWALGYLGLYVFYVVTV 244

>NCKX4_HUMAN (Q8NFF2) Sodium/potassium/calcium exchanger 4 precursor|
           (Na(+)/K(+)/Ca(2+)-exchange protein 4) (Solute carrier
           family 24 member 4)
          Length = 605

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 11/53 (20%), Positives = 28/53 (52%)
 Frame = +1

Query: 106 VQIDWRCFVRDVGFFLITLVALSIMLIVGKVTVWGAMLFVSIYVVYAFVVAAN 264
           V++ W    RD  ++ I+++ L + +   ++  W  ++ + +YV Y  ++  N
Sbjct: 179 VRLTWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILYVFYILIMKYN 231

>NCKX1_BOVIN (Q28139) Sodium/potassium/calcium exchanger 1|
           (Na(+)/K(+)/Ca(2+)-exchange protein 1) (Retinal rod
           Na-Ca+K exchanger)
          Length = 1216

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 13/56 (23%), Positives = 27/56 (48%)
 Frame = +1

Query: 106 VQIDWRCFVRDVGFFLITLVALSIMLIVGKVTVWGAMLFVSIYVVYAFVVAANELL 273
           + + W    RD+ F++  L+ L +  +   +  W ++L +  Y  Y F +  N+ L
Sbjct: 545 LNLTWWPLFRDITFYIFDLMMLILFFLDSLIAWWESVLLLLAYAFYVFTMKWNQQL 600

>NCKX4_MOUSE (Q8CGQ8) Sodium/potassium/calcium exchanger 4 precursor|
           (Na(+)/K(+)/Ca(2+)-exchange protein 4)
          Length = 605

 Score = 32.0 bits (71), Expect = 1.4
 Identities = 18/110 (16%), Positives = 45/110 (40%)
 Frame = +1

Query: 106 VQIDWRCFVRDVGFFLITLVALSIMLIVGKVTVWGAMLFVSIYVVYAFVVAANELLRKHA 285
           V++ W    RD  ++ ++++ L   +   ++  W  ++ + +YV Y  ++  N       
Sbjct: 179 VRLTWWAVCRDSVYYTLSVIVLIAFIYDEEIVWWEGLVLIILYVFYILIMKYN------M 232

Query: 286 RMLKFDVVTPLLPVRGSIFAQGIEEDDSVYSSLLEEDTSDEAAQVNTSLP 435
           +M  F          G+  +  +E+ + +Y    ++ +     QV    P
Sbjct: 233 KMQTFFTTKQKSIANGNPVSNELEDGNDLYDGSYDDPSVPLLGQVKEKPP 282

>POU47_BRARE (P79746) POU domain protein ZP-47|
          Length = 378

 Score = 31.6 bits (70), Expect = 1.8
 Identities = 14/33 (42%), Positives = 16/33 (48%)
 Frame = -1

Query: 237 HIDRHKQHSSPDGHLPDDQHNRQCHQGDQEESN 139
           H D H  H S  GH P  QH  Q HQ   + S+
Sbjct: 168 HEDHHSPHLSDHGH-PPSQHQHQSHQSHHDHSD 199

>NCKX2_CHICK (Q9IAL7) Sodium/potassium/calcium exchanger 2 precursor|
           (Na(+)/K(+)/Ca(2+)-exchange protein 2) (Retinal cone
           Na-Ca+K exchanger)
          Length = 651

 Score = 31.2 bits (69), Expect = 2.3
 Identities = 17/73 (23%), Positives = 32/73 (43%), Gaps = 4/73 (5%)
 Frame = +1

Query: 106 VQIDWRCFVRDVGFFLITLVALSIMLIVGKVTVWGAMLFVSIYVVYA----FVVAANELL 273
           + + W    RDV F+++ L+ L I  +   +  W ++  ++ Y  Y     F V   E +
Sbjct: 233 LNLTWWPLFRDVSFYIVDLILLIIFFLDNLIMWWESLTLLTAYFCYVTFMKFNVQVEEWV 292

Query: 274 RKHARMLKFDVVT 312
           +K     K +  T
Sbjct: 293 KKVLNRNKVEKAT 305

>ELAD_ECOLI (Q47013) Protein elaD|
          Length = 402

 Score = 30.8 bits (68), Expect = 3.1
 Identities = 25/70 (35%), Positives = 34/70 (48%), Gaps = 4/70 (5%)
 Frame = -1

Query: 240 NHIDRHKQHSSPDGHLPDDQH---NRQCHQGDQEESNIPHKAPPINLHILLRDGQRHS-P 73
           NH DR K++S+ + +  D QH   NR C+     ++NI H     NL I      +HS P
Sbjct: 341 NHADRFKKYSAEEQYEIDFQHRLANRNCYLDKYGDANINHYYR--NLEI------KHSQP 392

Query: 72  NNDAGNKHRS 43
            N A  K  S
Sbjct: 393 KNRASGKRVS 402

>ATKA_ALIAC (Q9XE11) Potassium-transporting ATPase A chain (EC 3.6.3.12)|
           (Potassium-translocating ATPase A chain) (ATP
           phosphohydrolase [potassium-transporting] A chain)
           (Potassium-binding and translocating subunit A)
          Length = 562

 Score = 30.4 bits (67), Expect = 4.0
 Identities = 18/60 (30%), Positives = 27/60 (45%), Gaps = 8/60 (13%)
 Frame = +1

Query: 118 WRCFVRDVGFFLITLVAL--------SIMLIVGKVTVWGAMLFVSIYVVYAFVVAANELL 273
           W C +  +G  LI    +        S  L +   T+ GA+L    Y+VYA+  A N +L
Sbjct: 254 WTCILEIMGMGLIPTALVFTAGHFLRSRRLAIVLCTLLGAILLAGAYIVYAYEAAGNPIL 313

>NO75_SOYBN (P08297) Early nodulin 75 precursor (N-75) (NGM-75)|
          Length = 309

 Score = 30.4 bits (67), Expect = 4.0
 Identities = 18/55 (32%), Positives = 21/55 (38%)
 Frame = -3

Query: 520 HSNPTMACQANHLSPDLSR*PHEKPTSTVAMMCLPGPPHHLYPPQEVNCKQNHPP 356
           H NP    Q  H  P   + PHEKP           PPH   PP+     +  PP
Sbjct: 109 HENPPPEHQPPHEKPPEHQPPHEKPPPEYE------PPHEKPPPEYQPPHEKPPP 157

>CUT_DROME (P10180) Homeobox protein cut|
          Length = 2175

 Score = 30.0 bits (66), Expect = 5.2
 Identities = 18/59 (30%), Positives = 24/59 (40%)
 Frame = -1

Query: 210 SPDGHLPDDQHNRQCHQGDQEESNIPHKAPPINLHILLRDGQRHSPNNDAGNKHRSAQH 34
           S D H    QH++Q HQ  Q+     H     + H L +     S +N A N H    H
Sbjct: 661 SEDAHHQQQQHHQQQHQHQQQHHQQQHLHQQ-HHHHLQQQPNSGSNSNPASNDHHHGHH 718

>SO_DROME (Q27350) Protein sine oculis|
          Length = 416

 Score = 30.0 bits (66), Expect = 5.2
 Identities = 23/74 (31%), Positives = 34/74 (45%)
 Frame = -1

Query: 231 DRHKQHSSPDGHLPDDQHNRQCHQGDQEESNIPHKAPPINLHILLRDGQRHSPNNDAGNK 52
           DR  +H   DG   D QH       + E S +P ++     H   +  Q+HSP N +GN 
Sbjct: 273 DRAAEHK--DGST-DKQHLDSSSDSEMEGSMLPSQSAQ---HQQQQQQQQHSPGNSSGNN 326

Query: 51  HRSAQHAVQPHIPA 10
           +   Q  +Q H+ A
Sbjct: 327 NGLHQQQLQ-HVAA 339

>RNC_HUMAN (Q9NRR4) Ribonuclease III (EC 3.1.26.3) (RNase III) (Drosha) (p241)|
          Length = 1374

 Score = 29.6 bits (65), Expect = 6.8
 Identities = 12/24 (50%), Positives = 14/24 (58%)
 Frame = -3

Query: 418 PGPPHHLYPPQEVNCKQNHPPLFL 347
           PG  HH +PP   N  QN+P  FL
Sbjct: 170 PGYSHHNFPPPSFNSFQNNPSSFL 193

>KLC2_HUMAN (Q9H0B6) Kinesin light chain 2 (KLC 2)|
          Length = 622

 Score = 29.6 bits (65), Expect = 6.8
 Identities = 17/67 (25%), Positives = 31/67 (46%), Gaps = 1/67 (1%)
 Frame = +1

Query: 355 EEDDSVYSSLLEEDTSDEAAQVN-TSLPQWMWASHVAIYSNQGRDGSPDRPLWGWNEEGR 531
           ++ +++Y  +L      E   VN  + P WM A       ++ RD +P      W +  +
Sbjct: 383 QDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREESKDKRRDSAPYGEYGSWYKACK 442

Query: 532 VDTSTLN 552
           VD+ T+N
Sbjct: 443 VDSPTVN 449

>NO75_LUPLU (Q06841) Early nodulin 75 protein (N-75) (NGM-75) (Fragment)|
          Length = 434

 Score = 29.3 bits (64), Expect = 8.9
 Identities = 17/56 (30%), Positives = 22/56 (39%)
 Frame = -3

Query: 520 HSNPTMACQANHLSPDLSR*PHEKPTSTVAMMCLPGPPHHLYPPQEVNCKQNHPPL 353
           H  P +     H  P +   P+EKP        L  PP H  PP E +     PP+
Sbjct: 111 HEKPPIEYSPPHEKPPVHEPPYEKPP-------LVHPPPHDKPPIEYHPPHEKPPI 159

>HXABA_BRARE (Q9DDU0) Homeobox protein Hox-A11a|
          Length = 284

 Score = 29.3 bits (64), Expect = 8.9
 Identities = 16/47 (34%), Positives = 21/47 (44%)
 Frame = -3

Query: 415 GPPHHLYPPQEVNCKQNHPPLFLVRRYFPSQEAMV*LHQTSASVRAS 275
           GP  H YP ++   K+  P +  V   FP   A    H TS +  AS
Sbjct: 78  GPLAHCYPSEDSVHKECLPAVTTVGEMFPKNNASAYYHSTSNTTSAS 124

>GBF_DICDI (P36417) G-box-binding factor (GBF)|
          Length = 708

 Score = 29.3 bits (64), Expect = 8.9
 Identities = 18/67 (26%), Positives = 28/67 (41%), Gaps = 5/67 (7%)
 Frame = -1

Query: 228 RHKQHSSPD-----GHLPDDQHNRQCHQGDQEESNIPHKAPPINLHILLRDGQRHSPNND 64
           +H QHS P            QHN+Q HQ  Q +  +  + P      L   G  ++ NN+
Sbjct: 222 QHHQHSQPQQQHQHNQQQQHQHNQQQHQQQQNQIQMVPQQP----QSLSNSGNNNNNNNN 277

Query: 63  AGNKHRS 43
             N + +
Sbjct: 278 NNNSNNN 284

>INVO_RAT (P48998) Involucrin|
          Length = 568

 Score = 29.3 bits (64), Expect = 8.9
 Identities = 19/72 (26%), Positives = 30/72 (41%)
 Frame = -1

Query: 231 DRHKQHSSPDGHLPDDQHNRQCHQGDQEESNIPHKAPPINLHILLRDGQRHSPNNDAGNK 52
           ++ K H  P+ HL   QH        Q E     K+P   LH L +  + H P+     K
Sbjct: 357 EKQKLHD-PELHLGKQQHQESQESELQVEKKQHEKSPEPELH-LGKQQELHEPDMTEDQK 414

Query: 51  HRSAQHAVQPHI 16
            + + H  + H+
Sbjct: 415 EKQSLHEPELHL 426


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 84,452,926
Number of Sequences: 219361
Number of extensions: 1816251
Number of successful extensions: 5477
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 5246
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5472
length of database: 80,573,946
effective HSP length: 106
effective length of database: 57,321,680
effective search space used: 5158951200
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)