>METK_BACHD (Q9K7Q9) S-adenosylmethionine synthetase (EC 2.5.1.6) (Methionine|
           adenosyltransferase) (AdoMet synthetase) (MAT)
          Length = 399

 Score = 30.4 bits (67), Expect = 1.7
 Identities = 12/27 (44%), Positives = 17/27 (62%)
 Frame = +3

Query: 108 AAYHHAGATPVAAPWRQKNQGAVLRRK 188
           AAY H G T V  PW Q ++  +LR++
Sbjct: 372 AAYGHFGRTDVELPWEQTDKAEILRQQ 398

>METH_MYCLE (Q49775) Methionine synthase (EC 2.1.1.13)|
           (5-methyltetrahydrofolate--homocysteine
           methyltransferase) (Methionine synthase, vitamin-B12
           dependent isozyme) (MS)
          Length = 1206

 Score = 29.3 bits (64), Expect = 3.8
 Identities = 15/39 (38%), Positives = 20/39 (51%)
 Frame = +3

Query: 12  VTEGGGHAPMTVMFQHTTAGAILQGTEDGVTLAAYHHAG 128
           +T+ G H P+ V     T G +L G+E G  LAA    G
Sbjct: 187 MTQAGRHIPVFVHVTVETTGTMLLGSEIGAALAAVEPLG 225

>FBXW7_DROME (Q9VZF4) F-box/WD-repeat protein 7 (F-box and WD-40 domain protein|
           7) (Protein archipelago)
          Length = 1326

 Score = 28.9 bits (63), Expect = 5.0
 Identities = 16/39 (41%), Positives = 22/39 (56%)
 Frame = -1

Query: 176 NSSLILLTPGSSYGSSSCVVIRCESNSVFCSLENSACCS 60
           + S   L  GSS G+SSC   R  S+S   S+E+S  C+
Sbjct: 450 SKSTAKLNLGSSLGASSCSQHRSGSSSTSKSMESSTSCT 488

>DLL3_RAT (O88671) Delta-like protein 3 precursor (Drosophila Delta homolog|
           3)
          Length = 589

 Score = 28.9 bits (63), Expect = 5.0
 Identities = 25/85 (29%), Positives = 31/85 (36%), Gaps = 7/85 (8%)
 Frame = -1

Query: 281 SMNCGCAHSFL*NASSQSQVTCCAMPCFQHILSA----ENSSLILLTPGSSYGSSSCVVI 114
           S  C C   F       S VTC   PCF   L       +S+ +   P +  GS+     
Sbjct: 297 SFECACPRGFYGPRCEVSGVTCADGPCFNGGLCVGGEDPDSAYVCHCPPAFQGSN----- 351

Query: 113 RCESNSVFCSL---ENSACCSMLKH 48
            CE     CSL   +N   C  L H
Sbjct: 352 -CERRVDRCSLQPCQNGGLCLDLGH 375

>TROP_HUMAN (Q12816) Trophinin (MAGE-D3 antigen)|
          Length = 1387

 Score = 28.9 bits (63), Expect = 5.0
 Identities = 25/78 (32%), Positives = 38/78 (48%), Gaps = 4/78 (5%)
 Frame = -1

Query: 389 YTIIPSTL--FTNIQSHQ--GTL*TIRCLMRLSAPWRRTSSMNCGCAHSFL*NASSQSQV 222
           + + PST   F+N  S    GTL T       S+ +   +S++ GCAHS   + SS++ +
Sbjct: 715 FGVAPSTSASFSNTASISFGGTLST-------SSSFSSAASISFGCAHSTSTSFSSEASI 767

Query: 221 TCCAMPCFQHILSAENSS 168
           +   MPC     S   SS
Sbjct: 768 SFGGMPCTSASFSGGVSS 785

>METK_BACSK (Q5WDZ8) S-adenosylmethionine synthetase (EC 2.5.1.6) (Methionine|
           adenosyltransferase) (AdoMet synthetase) (MAT)
          Length = 405

 Score = 28.9 bits (63), Expect = 5.0
 Identities = 14/31 (45%), Positives = 19/31 (61%)
 Frame = +3

Query: 108 AAYHHAGATPVAAPWRQKNQGAVLRRKDMLK 200
           AAY H G T V  PW   ++ A L ++D+LK
Sbjct: 372 AAYGHFGRTDVPLPWEATDKAAAL-KEDVLK 401

>DLL3_MOUSE (O88516) Delta-like protein 3 precursor (Drosophila Delta homolog|
           3) (M-Delta-3)
          Length = 592

 Score = 28.9 bits (63), Expect = 5.0
 Identities = 25/87 (28%), Positives = 31/87 (35%), Gaps = 7/87 (8%)
 Frame = -1

Query: 287 TSSMNCGCAHSFL*NASSQSQVTCCAMPCFQHILSA----ENSSLILLTPGSSYGSSSCV 120
           + S  C C   F       S VTC   PCF   L       +S+ +   P    GS+   
Sbjct: 291 SGSFECACPRGFYGLRCEVSGVTCADGPCFNGGLCVGGEDPDSAYVCHCPPGFQGSN--- 347

Query: 119 VIRCESNSVFCSL---ENSACCSMLKH 48
              CE     CSL   +N   C  L H
Sbjct: 348 ---CEKRVDRCSLQPCQNGGLCLDLGH 371

>METK_MYCPA (Q741G5) S-adenosylmethionine synthetase (EC 2.5.1.6) (Methionine|
           adenosyltransferase) (AdoMet synthetase) (MAT)
          Length = 403

 Score = 28.5 bits (62), Expect = 6.6
 Identities = 13/26 (50%), Positives = 15/26 (57%)
 Frame = +3

Query: 108 AAYHHAGATPVAAPWRQKNQGAVLRR 185
           AAY H G T V  PW Q N+   L+R
Sbjct: 376 AAYGHFGRTDVELPWEQLNKVDELKR 401

>BRCA1_MACMU (Q6J6I9) Breast cancer type 1 susceptibility protein homolog|
          Length = 1863

 Score = 28.5 bits (62), Expect = 6.6
 Identities = 19/58 (32%), Positives = 30/58 (51%)
 Frame = -1

Query: 245  NASSQSQVTCCAMPCFQHILSAENSSLILLTPGSSYGSSSCVVIRCESNSVFCSLENS 72
            N SS+ +     +PCFQH+L  + S++   T   S  ++ C+    E N    SL+NS
Sbjct: 1215 NLSSEDE----ELPCFQHLLFGKVSNIPSQTTRHSTVATECLSKNTEEN--LLSLKNS 1266

>NLTP4_ORYSA (Q42976) Nonspecific lipid-transfer protein 4 precursor (LTP 4)|
          Length = 121

 Score = 28.1 bits (61), Expect = 8.6
 Identities = 22/77 (28%), Positives = 30/77 (38%)
 Frame = -1

Query: 242 ASSQSQVTCCAMPCFQHILSAENSSLILLTPGSSYGSSSCVVIRCESNSVFCSLENSACC 63
           A S   VT    PC  +++  E          SS  SS C  +R  +     S +    C
Sbjct: 29  AVSCGDVTSSIAPCLSYVMGRE----------SSPSSSCCSGVRTLNGKASSSADRRTAC 78

Query: 62  SMLKHNGHGSMTSAFCN 12
           S LK     +M S+F N
Sbjct: 79  SCLK-----NMASSFRN 90

>DLL3_HUMAN (Q9NYJ7) Delta-like protein 3 precursor (Drosophila Delta homolog|
           3)
          Length = 618

 Score = 28.1 bits (61), Expect = 8.6
 Identities = 26/85 (30%), Positives = 31/85 (36%), Gaps = 7/85 (8%)
 Frame = -1

Query: 281 SMNCGCAHSFL*NASSQSQVTCCAMPCFQHIL----SAENSSLILLTPGSSYGSSSCVVI 114
           S  C C   F       S VTC   PCF   L    +  +S+ I   P    GS+     
Sbjct: 295 SFECTCPRGFYGLRCEVSGVTCADGPCFNGGLCVGGADPDSAYICHCPPGFQGSN----- 349

Query: 113 RCESNSVFCSLE---NSACCSMLKH 48
            CE     CSL+   N   C  L H
Sbjct: 350 -CEKRVDRCSLQPCRNGGLCLDLGH 373

>DCDA_ACTPA (O69203) Diaminopimelate decarboxylase (EC 4.1.1.20) (DAP|
           decarboxylase)
          Length = 437

 Score = 28.1 bits (61), Expect = 8.6
 Identities = 20/53 (37%), Positives = 26/53 (49%), Gaps = 12/53 (22%)
 Frame = +3

Query: 12  VTEGGGHAPMTVMFQHTTAGAIL-------QGTEDGVTLA-----AYHHAGAT 134
           V  GG  AP+TV+ +H  AG +L       +    G  LA     AYHHA A+
Sbjct: 350 VRRGGRRAPVTVVGRHCEAGDVLAEDVPLPEDVRAGDLLAVPVTGAYHHALAS 402

>METK_MYCLE (Q9CCQ4) S-adenosylmethionine synthetase (EC 2.5.1.6) (Methionine|
           adenosyltransferase) (AdoMet synthetase) (MAT)
          Length = 403

 Score = 28.1 bits (61), Expect = 8.6
 Identities = 13/26 (50%), Positives = 15/26 (57%)
 Frame = +3

Query: 108 AAYHHAGATPVAAPWRQKNQGAVLRR 185
           AAY H G T V  PW Q N+   L+R
Sbjct: 376 AAYGHFGRTDVELPWEQLNKVDDLKR 401

>ASX_DROME (Q9V727) Polycomb protein Asx (Additional sex combs)|
          Length = 1669

 Score = 28.1 bits (61), Expect = 8.6
 Identities = 23/71 (32%), Positives = 32/71 (45%), Gaps = 8/71 (11%)
 Frame = -1

Query: 260 HSFL*NASSQSQVTCCAMPCFQHILSAENSSLILL------TPGSSYGSSSCVVIRCESN 99
           H+F  ++SS +  T  A    +H    E+S L +       TP SS  S+SC      S 
Sbjct: 633 HNFFTSSSSSNTATTAANKLEEHSDKPEDSPLPIASSISGSTPASSITSTSCTSSSSSSA 692

Query: 98  SV--FCSLENS 72
           S+   CS  NS
Sbjct: 693 SMSSSCSSSNS 703


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,169,605
Number of Sequences: 219361
Number of extensions: 911409
Number of successful extensions: 3531
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 3409
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3530
length of database: 80,573,946
effective HSP length: 100
effective length of database: 58,637,846
effective search space used: 2228238148
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)