ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | baal6k15 |
|---|---|
| Clone Library Name | barley_pub |
>EXS_ARATH (Q9LYN8) Leucine-rich repeat receptor protein kinase EXS precursor| (EC 2.7.11.1) (Extra sporogenous cells protein) (EXCESS MICROSPOROCYTES1 protein) Length = 1192 Score = 82.0 bits (201), Expect = 1e-15 Identities = 70/228 (30%), Positives = 104/228 (45%), Gaps = 35/228 (15%) Frame = +1 Query: 1 DLQGEIPKKGVFSNASAVSLGGNSELCGGVPELHMPACPVASHRGTKIRYYLIRVLIPLF 180 +L+GE+P GV + S L GN ELCG V C + GTK+R + + Sbjct: 783 NLRGEVPSDGVCQDPSKALLSGNKELCGRVVGSD---CKI---EGTKLRSAW-GIAGLML 835 Query: 181 GFMSLVLLVYFLVLER--------------KMRRTRYE--------------SEAPLGEH 276 GF ++++ V+ L R +M +R + S PL + Sbjct: 836 GF-TIIVFVFVFSLRRWAMTKRVKQRDDPERMEESRLKGFVDQNLYFLSGSRSREPLSIN 894 Query: 277 FP-------KVSYNDLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQG 435 KV D+VEAT +FS+ N++G G +GTVY+ L K K+ + QG Sbjct: 895 IAMFEQPLLKVRLGDIVEATDHFSKKNIIGDGGFGTVYKACLPGEKTVAVKKLSEAKTQG 954 Query: 436 AERSFLSECEALRSVQHRNLVSIITACSTIDSDGSAFRALIYEFMPKG 579 R F++E E L V+H NLVS++ CS S + L+YE+M G Sbjct: 955 -NREFMAEMETLGKVKHPNLVSLLGYCSF-----SEEKLLVYEYMVNG 996
>BRL3_ARATH (Q9LJF3) Serine/threonine-protein kinase BRI1-like 3 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 3) Length = 1164 Score = 75.9 bits (185), Expect = 8e-14 Identities = 61/226 (26%), Positives = 98/226 (43%), Gaps = 33/226 (14%) Frame = +1 Query: 1 DLQGEIPKKGVFSNASAVSLGGNSELCGGVPELHMPAC-----PVASHRGTKIRYYLIRV 165 +L G IP G + NS LCG VP +P C P SH K + + Sbjct: 722 NLTGPIPFGGQLTTFPLTRYANNSGLCG-VP---LPPCSSGSRPTRSHAHPKKQSIATGM 777 Query: 166 LIPL-FGFMSLVLLVYFLVLERKMRRTRYESE---------------------------A 261 + F FM +V+L+ L RK+++ + E A Sbjct: 778 SAGIVFSFMCIVMLIMALYRARKVQKKEKQREKYIESLPTSGSSSWKLSSVHEPLSINVA 837 Query: 262 PLGEHFPKVSYNDLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAE 441 + K+++ L+EAT FS +++G G +G VY+ KL + K+ + QG + Sbjct: 838 TFEKPLRKLTFAHLLEATNGFSADSMIGSGGFGDVYKAKLADGSVVAIKKLIQVTGQG-D 896 Query: 442 RSFLSECEALRSVQHRNLVSIITACSTIDSDGSAFRALIYEFMPKG 579 R F++E E + ++HRNLV ++ C + R L+YE+M G Sbjct: 897 REFMAEMETIGKIKHRNLVPLLGYCKIGEE-----RLLVYEYMKYG 937
>BRL2_ARATH (Q9ZPS9) Serine/threonine-protein kinase BRI1-like 2 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 2) (Protein VASCULAR HIGHWAY 1) Length = 1143 Score = 72.8 bits (177), Expect = 7e-13 Identities = 60/234 (25%), Positives = 97/234 (41%), Gaps = 41/234 (17%) Frame = +1 Query: 1 DLQGEIPKKGVFSNASAVSLGGNSELCGGVPELHMPAC-------PVASHRGTKIRYYLI 159 +L G IP++G S A N LCG VP +P C P + G + ++ Sbjct: 694 ELTGPIPQRGQLSTLPATQYANNPGLCG-VP---LPECKNGNNQLPAGTEEGKRAKHGTR 749 Query: 160 R-------VLIPLFGFMSLVLLVYFLVLERKMRRTRYESE-------------------- 258 VL L S+ +L+ + + R RR +++ Sbjct: 750 AASWANSIVLGVLISAASVCILIVWAIAVRARRRDADDAKMLHSLQAVNSATTWKIEKEK 809 Query: 259 -------APLGEHFPKVSYNDLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVF 417 A K+ ++ L+EAT FS ++++G G +G V++ L K+ Sbjct: 810 EPLSINVATFQRQLRKLKFSQLIEATNGFSAASMIGHGGFGEVFKATLKDGSSVAIKKLI 869 Query: 418 NLEMQGAERSFLSECEALRSVQHRNLVSIITACSTIDSDGSAFRALIYEFMPKG 579 L QG +R F++E E L ++HRNLV ++ C + R L+YEFM G Sbjct: 870 RLSCQG-DREFMAEMETLGKIKHRNLVPLLGYCKIGEE-----RLLVYEFMQYG 917
>BRL1_ARATH (Q9ZWC8) Serine/threonine-protein kinase BRI1-like 1 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 1) Length = 1166 Score = 71.2 bits (173), Expect = 2e-12 Identities = 59/223 (26%), Positives = 94/223 (42%), Gaps = 30/223 (13%) Frame = +1 Query: 1 DLQGEIPKKGVFSNASAVSLGGNSELCGGV--PELHMPACPVASHRGTKIRYYLIRVLIP 174 +L G IP G + NS LCG P P P+ S K + V+ Sbjct: 722 NLTGPIPFGGQLTTFPVSRYANNSGLCGVPLRPCGSAPRRPITSRIHAKKQTVATAVIAG 781 Query: 175 L-FGFMSLVLLVYFLVLERKMRRTRYESE---------------------------APLG 270 + F FM V+LV L RK+++ + E A Sbjct: 782 IAFSFMCFVMLVMALYRVRKVQKKEQKREKYIESLPTSGSCSWKLSSVPEPLSINVATFE 841 Query: 271 EHFPKVSYNDLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSF 450 + K+++ L+EAT FS ++G G +G VY+ +L + K+ + QG +R F Sbjct: 842 KPLRKLTFAHLLEATNGFSAETMVGSGGFGEVYKAQLRDGSVVAIKKLIRITGQG-DREF 900 Query: 451 LSECEALRSVQHRNLVSIITACSTIDSDGSAFRALIYEFMPKG 579 ++E E + ++HRNLV ++ C + R L+YE+M G Sbjct: 901 MAEMETIGKIKHRNLVPLLGYCKVGEE-----RLLVYEYMKWG 938
>BRI1_ARATH (O22476) BRASSINOSTEROID INSENSITIVE 1 precursor (EC 2.7.11.1)| (AtBRI1) (Brassinosteroid LRR receptor kinase) Length = 1196 Score = 66.2 bits (160), Expect = 6e-11 Identities = 57/236 (24%), Positives = 94/236 (39%), Gaps = 43/236 (18%) Frame = +1 Query: 1 DLQGEIPKKGVFSNASAVSLGGNSELCGGVPELHMPACPVAS-------HRGTKIRYYLI 159 +L G IP+ G F N LCG +P C ++ R R + Sbjct: 737 NLSGPIPEMGQFETFPPAKFLNNPGLCG----YPLPRCDPSNADGYAHHQRSHGRRPASL 792 Query: 160 RVLIPLFGFMSLVLLVYFLVLERKMRRTRYESEAPLGEH--------------------- 276 + + S V + +++ R+MR+ R + EA L + Sbjct: 793 AGSVAMGLLFSFVCIFGLILVGREMRKRRRKKEAELEMYAEGHGNSGDRTANNTNWKLTG 852 Query: 277 ---------------FPKVSYNDLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVK 411 K+++ DL++AT F +L+G G +G VY+ L K Sbjct: 853 VKEALSINLAAFEKPLRKLTFADLLQATNGFHNDSLIGSGGFGDVYKAILKDGSAVAIKK 912 Query: 412 VFNLEMQGAERSFLSECEALRSVQHRNLVSIITACSTIDSDGSAFRALIYEFMPKG 579 + ++ QG +R F++E E + ++HRNLV ++ C D R L+YEFM G Sbjct: 913 LIHVSGQG-DREFMAEMETIGKIKHRNLVPLLGYCKVGDE-----RLLVYEFMKYG 962
>CLV1_ARATH (Q9SYQ8) Receptor protein kinase CLAVATA1 precursor (EC 2.7.11.1)| Length = 980 Score = 65.9 bits (159), Expect = 8e-11 Identities = 57/203 (28%), Positives = 104/203 (51%), Gaps = 10/203 (4%) Frame = +1 Query: 1 DLQGEIPKKGVFSNASAVSLGGNSELCGGVPELHMPACPV-----ASHRGTKIRYYLIRV 165 DL G +P G F + S GN+ LC +P H +CP + H T + + R+ Sbjct: 587 DLSGRVPLGGQFLVFNETSFAGNTYLC--LP--HRVSCPTRPGQTSDHNHTAL-FSPSRI 641 Query: 166 LIPLFGFMSLVLLVYFLVLERKMRRTRYESEAPLGEHFPKVSYN--DLVEATKNFSESNL 339 +I + ++ ++L+ + + ++ + +S A F K+ + D++E K E N+ Sbjct: 642 VITVIAAITGLILISVAIRQMNKKKNQ-KSLAWKLTAFQKLDFKSEDVLECLK---EENI 697 Query: 340 LGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERS---FLSECEALRSVQHRNLVSIIT 510 +GKG G VYRG + + ++VA+K L +G RS F +E + L ++HR++V ++ Sbjct: 698 IGKGGAGIVYRGSM-PNNVDVAIK--RLVGRGTGRSDHGFTAEIQTLGRIRHRHIVRLLG 754 Query: 511 ACSTIDSDGSAFRALIYEFMPKG 579 + D++ L+YE+MP G Sbjct: 755 YVANKDTN-----LLLYEYMPNG 772
>BRI1_LYCPE (Q8L899) Systemin receptor SR160 precursor (EC 2.7.11.1)| (Brassinosteroid LRR receptor kinase) Length = 1207 Score = 64.3 bits (155), Expect = 2e-10 Identities = 33/99 (33%), Positives = 56/99 (56%) Frame = +1 Query: 283 KVSYNDLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSEC 462 K+++ DL+EAT F +L+G G +G VY+ +L + K+ ++ QG +R F +E Sbjct: 875 KLTFADLLEATNGFHNDSLVGSGGFGDVYKAQLKDGSVVAIKKLIHVSGQG-DREFTAEM 933 Query: 463 EALRSVQHRNLVSIITACSTIDSDGSAFRALIYEFMPKG 579 E + ++HRNLV ++ C + R L+YE+M G Sbjct: 934 ETIGKIKHRNLVPLLGYCKVGEE-----RLLVYEYMKYG 967
>BRI1_LYCES (Q8GUQ5) Brassinosteroid LRR receptor kinase precursor (EC 2.7.11.1)| (tBRI1) (Altered brassinolide sensitivity 1) (Systemin receptor SR160) Length = 1207 Score = 64.3 bits (155), Expect = 2e-10 Identities = 33/99 (33%), Positives = 56/99 (56%) Frame = +1 Query: 283 KVSYNDLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSEC 462 K+++ DL+EAT F +L+G G +G VY+ +L + K+ ++ QG +R F +E Sbjct: 875 KLTFADLLEATNGFHNDSLVGSGGFGDVYKAQLKDGSVVAIKKLIHVSGQG-DREFTAEM 933 Query: 463 EALRSVQHRNLVSIITACSTIDSDGSAFRALIYEFMPKG 579 E + ++HRNLV ++ C + R L+YE+M G Sbjct: 934 ETIGKIKHRNLVPLLGYCKVGEE-----RLLVYEYMKYG 967
>SRK6_BRAOE (Q09092) Putative serine/threonine-protein kinase receptor| precursor (EC 2.7.11.1) (S-receptor kinase) (SRK) Length = 849 Score = 64.3 bits (155), Expect = 2e-10 Identities = 47/159 (29%), Positives = 76/159 (47%), Gaps = 29/159 (18%) Frame = +1 Query: 181 GFMSLVLLVYFLVLERKMRR----------TRYESEAPLGE------------------H 276 G L+LL+ F + +RK +R T+ P+ E Sbjct: 453 GVSVLLLLIMFCLWKRKQKRAKASAISIANTQRNQNLPMNEMVLSSKREFSGEYKFEELE 512 Query: 277 FPKVSYNDLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVK-VFNLEMQGAERSFL 453 P + +V+AT+NFS N LG+G +G VY+G+L+ K E+AVK + +QG + F+ Sbjct: 513 LPLIEMETVVKATENFSSCNKLGQGGFGIVYKGRLLDGK-EIAVKRLSKTSVQGTD-EFM 570 Query: 454 SECEALRSVQHRNLVSIITACSTIDSDGSAFRALIYEFM 570 +E + +QH NLV ++ C D + LIYE++ Sbjct: 571 NEVTLIARLQHINLVQVLGCCIEGDE-----KMLIYEYL 604
>PBS1_ARATH (Q9FE20) Serine/threonine-protein kinase PBS1 (EC 2.7.11.1)| (AvrPphB susceptible protein 1) Length = 456 Score = 62.8 bits (151), Expect = 7e-10 Identities = 37/97 (38%), Positives = 50/97 (51%) Frame = +1 Query: 289 SYNDLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSECEA 468 ++ +L AT NF LG+G +G VY+G+L VAVK + R FL E Sbjct: 75 AFRELAAATMNFHPDTFLGEGGFGRVYKGRLDSTGQVVAVKQLDRNGLQGNREFLVEVLM 134 Query: 469 LRSVQHRNLVSIITACSTIDSDGSAFRALIYEFMPKG 579 L + H NLV++I C+ D R L+YEFMP G Sbjct: 135 LSLLHHPNLVNLIGYCADGDQ-----RLLVYEFMPLG 166
>PSKR_ARATH (Q9ZVR7) Putative phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1008 Score = 62.8 bits (151), Expect = 7e-10 Identities = 64/219 (29%), Positives = 95/219 (43%), Gaps = 26/219 (11%) Frame = +1 Query: 1 DLQGEIPKKGVFSNASAVSLGGNSELCGGVPELHMPACPVASH-----RGTKIRYYLIRV 165 +L G IP G F S N LCG H C + R + R I + Sbjct: 606 NLSGVIPSGGQFQTFPNSSFESN-HLCGE----HRFPCSEGTESALIKRSRRSRGGDIGM 660 Query: 166 LIPL-FGFMSLVLLVYFLVLERKMRRTRYESEAP---------LGEHFPKV--------- 288 I + FG + L+ L+ +VL + R + E LGE K+ Sbjct: 661 AIGIAFGSVFLLTLLSLIVLRARRRSGEVDPEIEESESMNRKELGEIGSKLVVLFQSNDK 720 Query: 289 --SYNDLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSEC 462 SY+DL+++T +F ++N++G G +G VY+ L K +VA+K + + ER F +E Sbjct: 721 ELSYDDLLDSTNSFDQANIIGCGGFGMVYKATLPDGK-KVAIKKLSGDCGQIEREFEAEV 779 Query: 463 EALRSVQHRNLVSIITACSTIDSDGSAFRALIYEFMPKG 579 E L QH NLV + C + R LIY +M G Sbjct: 780 ETLSRAQHPNLVLLRGFCFYKND-----RLLIYSYMENG 813
>SIRK_ARATH (O64483) Senescence-induced receptor-like serine/threonine-protein| kinase precursor (FLG22-induced receptor-like kinase 1) Length = 876 Score = 61.6 bits (148), Expect = 2e-09 Identities = 46/140 (32%), Positives = 70/140 (50%), Gaps = 5/140 (3%) Frame = +1 Query: 166 LIPLFGFMSLVLLVYFLVLERKMRR-----TRYESEAPLGEHFPKVSYNDLVEATKNFSE 330 +IPL +V+L+ L L R+ ++ T E PL Y+++V T NF Sbjct: 519 IIPLVVVGIIVVLLTALALFRRFKKKQQRGTLGERNGPLKTAKRYFKYSEVVNITNNFER 578 Query: 331 SNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRNLVSIIT 510 ++GKG +G VY G V + +VAVKV + E + F +E + L V H NL S++ Sbjct: 579 --VIGKGGFGKVYHG--VINGEQVAVKVLSEESAQGYKEFRAEVDLLMRVHHTNLTSLVG 634 Query: 511 ACSTIDSDGSAFRALIYEFM 570 C+ I+ LIYE+M Sbjct: 635 YCNEIN-----HMVLIYEYM 649
>BAK1_ARATH (Q94F62) BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1| precursor (EC 2.7.11.1) (BRI1-associated receptor kinase 1) (Somatic embryogenesis receptor-like kinase 3) Length = 615 Score = 61.6 bits (148), Expect = 2e-09 Identities = 56/204 (27%), Positives = 87/204 (42%), Gaps = 12/204 (5%) Frame = +1 Query: 4 LQGEIPKKGVFSNASAVSLGGNSELCG-----GVPELHMPACPVASHRGTKIRYYLIRVL 168 L G+IP G FS + +S N++L P P P S+R T + Sbjct: 176 LTGDIPVNGSFSLFTPISFA-NTKLTPLPASPPPPISPTPPSPAGSNRITGAIAGGVAAG 234 Query: 169 IPLFGFMSLVLLVYFLVLERKMRRTRY-------ESEAPLGEHFPKVSYNDLVEATKNFS 327 L + + L ++ RK + + + E LG+ + S +L A+ NFS Sbjct: 235 AALLFAVPAIALAWW---RRKKPQDHFFDVPAEEDPEVHLGQ-LKRFSLRELQVASDNFS 290 Query: 328 ESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRNLVSII 507 N+LG+G +G VY+G+L L ++ QG E F +E E + HRNL+ + Sbjct: 291 NKNILGRGGFGKVYKGRLADGTLVAVKRLKEERTQGGELQFQTEVEMISMAVHRNLLRLR 350 Query: 508 TACSTIDSDGSAFRALIYEFMPKG 579 C T R L+Y +M G Sbjct: 351 GFCMT-----PTERLLVYPYMANG 369
>RPK1_IPONI (P93194) Receptor-like protein kinase precursor (EC 2.7.11.1)| Length = 1109 Score = 60.8 bits (146), Expect = 3e-09 Identities = 49/174 (28%), Positives = 76/174 (43%), Gaps = 12/174 (6%) Frame = +1 Query: 19 PKKGVFSNASAVSLGGNSELCGGVPELHMPACPVAS------------HRGTKIRYYLIR 162 P F N+S S GNS+LC P + ACP +S G + Sbjct: 707 PSLTKFLNSSPTSFSGNSDLCINCPADGL-ACPESSILRPCNMQSNTGKGGLSTLGIAMI 765 Query: 163 VLIPLFGFMSLVLLVYFLVLERKMRRTRYESEAPLGEHFPKVSYNDLVEATKNFSESNLL 342 VL L + L L FL L K A G+ N ++EAT+N ++ ++ Sbjct: 766 VLGALLFIICLFLFSAFLFLHCKKSVQEIAISAQEGDGS---LLNKVLEATENLNDKYVI 822 Query: 343 GKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRNLVSI 504 GKG++GT+Y+ L K+ K+ ++ S + E E + V+HRNL+ + Sbjct: 823 GKGAHGTIYKATLSPDKVYAVKKLVFTGIKNGSVSMVREIETIGKVRHRNLIKL 876
>RLCK7_ARATH (Q9LQQ8) Probable serine/threonine-protein kinase RLCKVII (EC| 2.7.11.1) Length = 423 Score = 60.5 bits (145), Expect = 3e-09 Identities = 36/106 (33%), Positives = 55/106 (51%), Gaps = 2/106 (1%) Frame = +1 Query: 268 GEHFPKVSYNDLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAE-- 441 G+ ++ +L EAT NF LG+G +G V++G + KL+ V + L+ G + Sbjct: 85 GKKAQTFTFQELAEATGNFRSDCFLGEGGFGKVFKGTI--EKLDQVVAIKQLDRNGVQGI 142 Query: 442 RSFLSECEALRSVQHRNLVSIITACSTIDSDGSAFRALIYEFMPKG 579 R F+ E L H NLV +I C+ D R L+YE+MP+G Sbjct: 143 REFVVEVLTLSLADHPNLVKLIGFCAEGDQ-----RLLVYEYMPQG 183
>APK1A_ARATH (Q06548) Protein kinase APK1A, chloroplast precursor (EC 2.7.11.1)| Length = 410 Score = 58.9 bits (141), Expect = 1e-08 Identities = 37/121 (30%), Positives = 58/121 (47%), Gaps = 9/121 (7%) Frame = +1 Query: 244 RYESEAPLGEHFPKVSYNDLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLE-------- 399 R E E + S+ +L AT+NF ++LG+G +G V++G + + L Sbjct: 42 RTEGEILQSPNLKSFSFAELKSATRNFRPDSVLGEGGFGCVFKGWIDEKSLTASRPGTGL 101 Query: 400 -VAVKVFNLEMQGAERSFLSECEALRSVQHRNLVSIITACSTIDSDGSAFRALIYEFMPK 576 +AVK N + + +L+E L HR+LV +I C R L+YEFMP+ Sbjct: 102 VIAVKKLNQDGWQGHQEWLAEVNYLGQFSHRHLVKLIGYCLE-----DEHRLLVYEFMPR 156 Query: 577 G 579 G Sbjct: 157 G 157
>KPRO_MAIZE (P17801) Putative receptor protein kinase ZmPK1 precursor (EC| 2.7.11.1) Length = 817 Score = 58.5 bits (140), Expect = 1e-08 Identities = 47/135 (34%), Positives = 71/135 (52%), Gaps = 4/135 (2%) Frame = +1 Query: 187 MSLVLLVYFLVLERKMRRTR-YESEA---PLGEHFPKVSYNDLVEATKNFSESNLLGKGS 354 +S + +F VL+R++R + + SE + +F + SY +LV+AT+ F LG+G Sbjct: 487 VSFISFAWFFVLKRELRPSELWASEKGYKAMTSNFRRYSYRELVKATRKFKVE--LGRGE 544 Query: 355 YGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRNLVSIITACSTIDSD 534 GTVY+G L + VAVK QG E F +E + + H NLV I C S+ Sbjct: 545 SGTVYKGVLEDDR-HVAVKKLENVRQGKE-VFQAELSVIGRINHMNLVRIWGFC----SE 598 Query: 535 GSAFRALIYEFMPKG 579 GS R L+ E++ G Sbjct: 599 GS-HRLLVSEYVENG 612
>CX32_ARATH (P27450) Probable serine/threonine-protein kinase Cx32, chloroplast| precursor (EC 2.7.11.1) Length = 419 Score = 58.2 bits (139), Expect = 2e-08 Identities = 39/106 (36%), Positives = 53/106 (50%), Gaps = 9/106 (8%) Frame = +1 Query: 289 SYNDLVEATKNFSESNLLGKGSYGTVYRG---------KLVQHKLEVAVKVFNLEMQGAE 441 ++ DL ATKNF ++LG+G +G VYRG V + VA+K N E Sbjct: 75 NFLDLKTATKNFKPDSMLGQGGFGKVYRGWVDATTLAPSRVGSGMIVAIKRLNSESVQGF 134 Query: 442 RSFLSECEALRSVQHRNLVSIITACSTIDSDGSAFRALIYEFMPKG 579 + SE L + HRNLV ++ C D + L+YEFMPKG Sbjct: 135 AEWRSEVNFLGMLSHRNLVKLLGYCRE-DKE----LLLVYEFMPKG 175
>APK1B_ARATH (P46573) Protein kinase APK1B, chloroplast precursor (EC 2.7.11.1)| Length = 412 Score = 57.4 bits (137), Expect = 3e-08 Identities = 36/121 (29%), Positives = 58/121 (47%), Gaps = 9/121 (7%) Frame = +1 Query: 244 RYESEAPLGEHFPKVSYNDLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLE-------- 399 R E E + ++ +L AT+NF ++LG+G +G+V++G + + L Sbjct: 43 RTEGEILQSPNLKSFTFAELKAATRNFRPDSVLGEGGFGSVFKGWIDEQTLTASKPGTGV 102 Query: 400 -VAVKVFNLEMQGAERSFLSECEALRSVQHRNLVSIITACSTIDSDGSAFRALIYEFMPK 576 +AVK N + + +L+E L H NLV +I C R L+YEFMP+ Sbjct: 103 VIAVKKLNQDGWQGHQEWLAEVNYLGQFSHPNLVKLIGYCLE-----DEHRLLVYEFMPR 157 Query: 577 G 579 G Sbjct: 158 G 158
>TMK1_ARATH (P43298) Putative receptor protein kinase TMK1 precursor (EC| 2.7.11.1) Length = 942 Score = 57.0 bits (136), Expect = 4e-08 Identities = 36/100 (36%), Positives = 55/100 (55%), Gaps = 2/100 (2%) Frame = +1 Query: 286 VSYNDLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAE--RSFLSE 459 +S L T NFS N+LG G +G VY+G+L ++AVK + + F SE Sbjct: 576 ISIQVLRSVTNNFSSDNILGSGGFGVVYKGEL-HDGTKIAVKRMENGVIAGKGFAEFKSE 634 Query: 460 CEALRSVQHRNLVSIITACSTIDSDGSAFRALIYEFMPKG 579 L V+HR+LV+++ C DG+ + L+YE+MP+G Sbjct: 635 IAVLTKVRHRHLVTLLGYC----LDGNE-KLLVYEYMPQG 669
>PSKR_DAUCA (Q8LPB4) Phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1021 Score = 56.6 bits (135), Expect = 5e-08 Identities = 54/216 (25%), Positives = 95/216 (43%), Gaps = 24/216 (11%) Frame = +1 Query: 4 LQGEIPKKGVFSNASAVSLGGNSELCGGVPELHMPACPVA--SHRGTKIRYYL-IRVLIP 174 L G IP F S GN LCG H C + S G+ ++ IR ++ Sbjct: 617 LSGPIPTGVQFQTFPNSSFEGNQGLCGE----HASPCHITDQSPHGSAVKSKKNIRKIVA 672 Query: 175 L-----FGFMSLVLLVYFLVLERKMR------RTRYESEAPLG----------EHFPKVS 291 + G + L+ + ++L R + E LG + ++S Sbjct: 673 VAVGTGLGTVFLLTVTLLIILRTTSRGEVDPEKKADADEIELGSRSVVLFHNKDSNNELS 732 Query: 292 YNDLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSECEAL 471 +D++++T +F+++N++G G +G VY+ L +VA+K + + +R F +E E L Sbjct: 733 LDDILKSTSSFNQANIIGCGGFGLVYKATL-PDGTKVAIKRLSGDTGQMDREFQAEVETL 791 Query: 472 RSVQHRNLVSIITACSTIDSDGSAFRALIYEFMPKG 579 QH NLV ++ C+ + + LIY +M G Sbjct: 792 SRAQHPNLVHLLGYCNYKND-----KLLIYSYMDNG 822
>NAK_ARATH (P43293) Probable serine/threonine-protein kinase NAK (EC 2.7.11.1)| Length = 389 Score = 56.2 bits (134), Expect = 7e-08 Identities = 37/121 (30%), Positives = 57/121 (47%), Gaps = 9/121 (7%) Frame = +1 Query: 244 RYESEAPLGEHFPKVSYNDLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLE-------- 399 R E E + S ++L AT+NF +++G+G +G V++G + + L Sbjct: 42 RTEGEILQNANLKNFSLSELKSATRNFRPDSVVGEGGFGCVFKGWIDESSLAPSKPGTGI 101 Query: 400 -VAVKVFNLEMQGAERSFLSECEALRSVQHRNLVSIITACSTIDSDGSAFRALIYEFMPK 576 +AVK N E R +L+E L + H NLV +I C R L+YEFM + Sbjct: 102 VIAVKRLNQEGFQGHREWLAEINYLGQLDHPNLVKLIGYCLE-----EEHRLLVYEFMTR 156 Query: 577 G 579 G Sbjct: 157 G 157
>RLK5_ARATH (P47735) Receptor-like protein kinase 5 precursor (EC 2.7.11.1)| Length = 999 Score = 54.7 bits (130), Expect = 2e-07 Identities = 45/162 (27%), Positives = 81/162 (50%), Gaps = 12/162 (7%) Frame = +1 Query: 130 RGTKIRY-YLIRVLIPLFGFMSLVLLVYFLVLERKMRRTRYES-EAPLGEHFPKVSYNDL 303 R I Y +++ + L G + +V +V F+ RK+R + + A F K+ +++ Sbjct: 618 RSKNIGYVWILLTIFLLAGLVFVVGIVMFIAKCRKLRALKSSTLAASKWRSFHKLHFSEH 677 Query: 304 VEATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERS----------FL 453 E E N++G GS G VY+ +L ++ VAVK N ++G + F Sbjct: 678 -EIADCLDEKNVIGFGSSGKVYKVELRGGEV-VAVKKLNKSVKGGDDEYSSDSLNRDVFA 735 Query: 454 SECEALRSVQHRNLVSIITACSTIDSDGSAFRALIYEFMPKG 579 +E E L +++H+++V + CS+ D + L+YE+MP G Sbjct: 736 AEVETLGTIRHKSIVRLWCCCSSGDC-----KLLVYEYMPNG 772
>CRI4_MAIZE (O24585) Putative receptor protein kinase CRINKLY4 precursor (EC| 2.7.11.1) Length = 901 Score = 54.3 bits (129), Expect = 2e-07 Identities = 34/99 (34%), Positives = 59/99 (59%), Gaps = 2/99 (2%) Frame = +1 Query: 289 SYNDLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVK--VFNLEMQGAERSFLSEC 462 SY +L +AT FSE + +GKGS+ V++G +++ VAVK + +++ + + F +E Sbjct: 494 SYEELEQATGGFSEDSQVGKGSFSCVFKG-ILRDGTVVAVKRAIKASDVKKSSKEFHNEL 552 Query: 463 EALRSVQHRNLVSIITACSTIDSDGSAFRALIYEFMPKG 579 + L + H +L++++ C DGS R L+YEFM G Sbjct: 553 DLLSRLNHAHLLNLLGYC----EDGSE-RLLVYEFMAHG 586
>NORK_MEDTR (Q8L4H4) Nodulation receptor kinase precursor (EC 2.7.11.1) (Does| not make infections protein 2) (Symbiosis receptor-like kinase) (MtSYMRK) Length = 925 Score = 53.5 bits (127), Expect = 4e-07 Identities = 33/91 (36%), Positives = 50/91 (54%) Frame = +1 Query: 307 EATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSECEALRSVQH 486 +AT+ + L+G+G +G+VYRG L + EVAVKV + R F +E L ++QH Sbjct: 593 QATEQYK--TLIGEGGFGSVYRGTLDDGQ-EVAVKVRSSTSTQGTREFDNELNLLSAIQH 649 Query: 487 RNLVSIITACSTIDSDGSAFRALIYEFMPKG 579 NLV ++ C+ D + L+Y FM G Sbjct: 650 ENLVPLLGYCNEYDQ-----QILVYPFMSNG 675
>NORK_PEA (Q8LKZ1) Nodulation receptor kinase precursor (EC 2.7.11.1)| Length = 924 Score = 53.1 bits (126), Expect = 6e-07 Identities = 31/81 (38%), Positives = 45/81 (55%) Frame = +1 Query: 337 LLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRNLVSIITAC 516 L+G+G +G+VYRG L + EVAVKV + R F +E L ++QH NLV ++ C Sbjct: 600 LIGEGGFGSVYRGTLDDGQ-EVAVKVRSATSTQGTREFDNELNLLSAIQHENLVPLLGYC 658 Query: 517 STIDSDGSAFRALIYEFMPKG 579 + D + L+Y FM G Sbjct: 659 NEYDQ-----QILVYPFMSNG 674
>IRAK1_HUMAN (P51617) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) Length = 712 Score = 51.6 bits (122), Expect = 2e-06 Identities = 33/98 (33%), Positives = 48/98 (48%), Gaps = 4/98 (4%) Frame = +1 Query: 298 DLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVF----NLEMQGAERSFLSECE 465 ++ T NFSE +G+G +G VYR V AVK +LE ++SFL+E E Sbjct: 204 EISRGTHNFSEELKIGEGGFGCVYRA--VMRNTVYAVKRLKENADLEWTAVKQSFLTEVE 261 Query: 466 ALRSVQHRNLVSIITACSTIDSDGSAFRALIYEFMPKG 579 L +H N+V C+ + F L+Y F+P G Sbjct: 262 QLSRFRHPNIVDFAGYCAQ-----NGFYCLVYGFLPNG 294
>KPEL_DROME (Q05652) Probable serine/threonine-protein kinase pelle (EC| 2.7.11.1) Length = 501 Score = 50.4 bits (119), Expect = 4e-06 Identities = 28/84 (33%), Positives = 47/84 (55%), Gaps = 6/84 (7%) Frame = +1 Query: 271 EHFPKVSYNDLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSF 450 E ++ Y +L AT +S N LG+G +G VYRGK Q L+VA+KV N ++ Sbjct: 196 ESLLEIDYAELENATDGWSPDNRLGQGGFGDVYRGKWKQ--LDVAIKVMNYRSPNIDQKM 253 Query: 451 L------SECEALRSVQHRNLVSI 504 + +E + L S++H N++++ Sbjct: 254 VELQQSYNELKYLNSIRHDNILAL 277
>IRAK1_MOUSE (Q62406) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK) Length = 710 Score = 49.7 bits (117), Expect = 6e-06 Identities = 33/98 (33%), Positives = 48/98 (48%), Gaps = 4/98 (4%) Frame = +1 Query: 298 DLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVF----NLEMQGAERSFLSECE 465 ++ + T NFSE +G+G +G VYR V AVK +LE ++SFL+E E Sbjct: 204 EISQGTCNFSEELRIGEGGFGCVYRA--VMRNTTYAVKRLKEEADLEWTMVKQSFLTEVE 261 Query: 466 ALRSVQHRNLVSIITACSTIDSDGSAFRALIYEFMPKG 579 L +H N+V C+ S L+Y F+P G Sbjct: 262 QLSRFRHPNIVDFAGYCAE-----SGLYCLVYGFLPNG 294
>IRAK4_MOUSE (Q8R4K2) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) Length = 459 Score = 47.4 bits (111), Expect = 3e-05 Identities = 34/111 (30%), Positives = 55/111 (49%), Gaps = 10/111 (9%) Frame = +1 Query: 277 FPKVSYNDLVEATKNFSES------NLLGKGSYGTVYRGKLVQHKLEVAVK----VFNLE 426 F S+++L T NF E N +G+G +G VY+G + + VAVK + + Sbjct: 165 FHSFSFHELKSITNNFDEQPASAGGNRMGEGGFGVVYKGCV--NNTIVAVKKLGAMVEIS 222 Query: 427 MQGAERSFLSECEALRSVQHRNLVSIITACSTIDSDGSAFRALIYEFMPKG 579 + ++ F E + + + QH NLV ++ S DSD L+Y +MP G Sbjct: 223 TEELKQQFDQEIKVMATCQHENLVELLGFSS--DSDN---LCLVYAYMPNG 268
>FPS_DROME (P18106) Tyrosine-protein kinase Fps85D (EC 2.7.10.2) (dFer)| Length = 1325 Score = 47.0 bits (110), Expect = 4e-05 Identities = 23/60 (38%), Positives = 35/60 (58%), Gaps = 1/60 (1%) Frame = +1 Query: 340 LGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAE-RSFLSECEALRSVQHRNLVSIITAC 516 +G+G++G VY+ KL KL+VAVK + + + R FL E L+ H N+V +I C Sbjct: 1069 IGRGNFGDVYKAKLKSTKLDVAVKTCRMTLPDEQKRKFLQEGRILKQYDHPNIVKLIGIC 1128
>IRAK4_HUMAN (Q9NWZ3) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) (NY-REN-64 antigen) Length = 460 Score = 46.6 bits (109), Expect = 5e-05 Identities = 33/111 (29%), Positives = 53/111 (47%), Gaps = 10/111 (9%) Frame = +1 Query: 277 FPKVSYNDLVEATKNFSE------SNLLGKGSYGTVYRGKLVQHKLEVAVK----VFNLE 426 F S+ +L T NF E N +G+G +G VY+G + + VAVK + ++ Sbjct: 165 FHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYV--NNTTVAVKKLAAMVDIT 222 Query: 427 MQGAERSFLSECEALRSVQHRNLVSIITACSTIDSDGSAFRALIYEFMPKG 579 + ++ F E + + QH NLV ++ SDG L+Y +MP G Sbjct: 223 TEELKQQFDQEIKVMAKCQHENLVELL----GFSSDGDDL-CLVYVYMPNG 268
>FLK_RAT (P09760) Tyrosine-protein kinase FLK (EC 2.7.10.2) (Fragment)| Length = 323 Score = 45.1 bits (105), Expect = 1e-04 Identities = 26/69 (37%), Positives = 40/69 (57%), Gaps = 1/69 (1%) Frame = +1 Query: 316 KNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEM-QGAERSFLSECEALRSVQHRN 492 ++ S LLGKG++G VY+G L + K VAVK ++ Q + FL E + L+ H N Sbjct: 62 EDVSLGELLGKGNFGEVYKGTL-KDKTPVAVKTCKEDLPQELKIKFLQEAKILKQYDHPN 120 Query: 493 LVSIITACS 519 +V +I C+ Sbjct: 121 IVKLIGVCT 129
>MERTK_HUMAN (Q12866) Proto-oncogene tyrosine-protein kinase MER precursor (EC| 2.7.10.1) (C-mer) (Receptor tyrosine kinase MerTK) Length = 999 Score = 45.1 bits (105), Expect = 1e-04 Identities = 27/86 (31%), Positives = 41/86 (47%), Gaps = 5/86 (5%) Frame = +1 Query: 337 LLGKGSYGTVYRGKLVQH---KLEVAVKVFNLEMQGAER--SFLSECEALRSVQHRNLVS 501 +LG+G +G+V G L Q L+VAVK L+ FLSE ++ H N++ Sbjct: 592 ILGEGEFGSVMEGNLKQEDGTSLKVAVKTMKLDNSSHREIEEFLSEAACMKDFSHPNVIR 651 Query: 502 IITACSTIDSDGSAFRALIYEFMPKG 579 ++ C + S G +I FM G Sbjct: 652 LLGVCIEMSSQGIPKPMVILPFMKYG 677
>FER_HUMAN (P16591) Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2)| (p94-FER) (c-FER) Length = 822 Score = 44.7 bits (104), Expect = 2e-04 Identities = 25/62 (40%), Positives = 37/62 (59%), Gaps = 1/62 (1%) Frame = +1 Query: 337 LLGKGSYGTVYRGKLVQHKLEVAVKVFNLEM-QGAERSFLSECEALRSVQHRNLVSIITA 513 LLGKG++G VY+G L + K VAVK ++ Q + FL E + L+ H N+V +I Sbjct: 568 LLGKGNFGEVYKGTL-KDKTSVAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGV 626 Query: 514 CS 519 C+ Sbjct: 627 CT 628
>ABL_FSVHY (P10447) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 439 Score = 44.3 bits (103), Expect = 3e-04 Identities = 22/60 (36%), Positives = 32/60 (53%) Frame = +1 Query: 340 LGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRNLVSIITACS 519 LG G YG VY G ++ L VAVK + E FL E ++ ++H NLV ++ C+ Sbjct: 197 LGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVE-EFLKEAAVMKEIKHPNLVQLLGVCT 255
>PHO85_DEBHA (Q6BRY2) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 330 Score = 44.3 bits (103), Expect = 3e-04 Identities = 25/90 (27%), Positives = 47/90 (52%), Gaps = 1/90 (1%) Frame = +1 Query: 310 ATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEM-QGAERSFLSECEALRSVQH 486 ++ F + LG+G+Y TVY+G+ + VA+K NL+ +G + + E ++ + H Sbjct: 4 SSSQFQQLEKLGEGTYATVYKGRNRTNGQLVALKEINLDSEEGTPSTAIREISLMKELDH 63 Query: 487 RNLVSIITACSTIDSDGSAFRALIYEFMPK 576 N+V++ T + L++EFM K Sbjct: 64 ENIVTLYDVIHTENK-----LTLVFEFMDK 88
>BMPR2_HUMAN (Q13873) Bone morphogenetic protein receptor type-2 precursor (EC| 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II) Length = 1038 Score = 44.3 bits (103), Expect = 3e-04 Identities = 28/89 (31%), Positives = 44/89 (49%), Gaps = 2/89 (2%) Frame = +1 Query: 319 NFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSECEALR--SVQHRN 492 N L+G+G YG VY+G L + VAVKVF+ ++F++E R ++H N Sbjct: 202 NLKLLELIGRGRYGAVYKGSLDER--PVAVKVFSF---ANRQNFINEKNIYRVPLMEHDN 256 Query: 493 LVSIITACSTIDSDGSAFRALIYEFMPKG 579 + I + +DG L+ E+ P G Sbjct: 257 IARFIVGDERVTADGRMEYLLVMEYYPNG 285
>ABL1_HUMAN (P00519) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1130 Score = 44.3 bits (103), Expect = 3e-04 Identities = 22/60 (36%), Positives = 32/60 (53%) Frame = +1 Query: 340 LGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRNLVSIITACS 519 LG G YG VY G ++ L VAVK + E FL E ++ ++H NLV ++ C+ Sbjct: 248 LGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVE-EFLKEAAVMKEIKHPNLVQLLGVCT 306
>IRAK3_HUMAN (Q9Y616) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 596 Score = 44.3 bits (103), Expect = 3e-04 Identities = 32/102 (31%), Positives = 52/102 (50%), Gaps = 4/102 (3%) Frame = +1 Query: 286 VSYNDLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLE--MQGAE--RSFL 453 +S+ +++E T+NF + L+G+G VYR ++ L AVK+F E MQ + + FL Sbjct: 153 ISFQNIIEGTRNFHKDFLIGEGEIFEVYRVEI--QNLTYAVKLFKQEKKMQCKKHWKRFL 210 Query: 454 SECEALRSVQHRNLVSIITACSTIDSDGSAFRALIYEFMPKG 579 SE E L H N++ + + + LIY +M G Sbjct: 211 SELEVLLLFHHPNILELAAYFTETEK-----FCLIYPYMRNG 247
>ABL_MLVAB (P00521) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 746 Score = 44.3 bits (103), Expect = 3e-04 Identities = 22/60 (36%), Positives = 32/60 (53%) Frame = +1 Query: 340 LGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRNLVSIITACS 519 LG G YG VY G ++ L VAVK + E FL E ++ ++H NLV ++ C+ Sbjct: 134 LGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVE-EFLKEAAVMKEIKHPNLVQLLGVCT 192
>ABL1_MOUSE (P00520) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1123 Score = 44.3 bits (103), Expect = 3e-04 Identities = 22/60 (36%), Positives = 32/60 (53%) Frame = +1 Query: 340 LGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRNLVSIITACS 519 LG G YG VY G ++ L VAVK + E FL E ++ ++H NLV ++ C+ Sbjct: 248 LGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVE-EFLKEAAVMKEIKHPNLVQLLGVCT 306
>BMPR2_MOUSE (O35607) Bone morphogenetic protein receptor type-2 precursor (EC| 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II) (BRK-3) Length = 1038 Score = 43.9 bits (102), Expect = 3e-04 Identities = 28/89 (31%), Positives = 44/89 (49%), Gaps = 2/89 (2%) Frame = +1 Query: 319 NFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSECEALR--SVQHRN 492 N L+G+G YG VY+G L + VAVKVF+ ++F++E R ++H N Sbjct: 202 NLKLLELIGRGRYGAVYKGSLDER--PVAVKVFSF---ANRQNFINEKNIYRVPLMEHDN 256 Query: 493 LVSIITACSTIDSDGSAFRALIYEFMPKG 579 + I + +DG L+ E+ P G Sbjct: 257 IARFIVGDERLTADGRMEYLLVMEYYPNG 285
>MERTK_MOUSE (Q60805) Proto-oncogene tyrosine-protein kinase MER precursor (EC| 2.7.10.1) (C-mer) (Receptor tyrosine kinase MerTK) Length = 994 Score = 43.5 bits (101), Expect = 4e-04 Identities = 27/86 (31%), Positives = 41/86 (47%), Gaps = 5/86 (5%) Frame = +1 Query: 337 LLGKGSYGTVYRGKLVQH---KLEVAVKVFNLE--MQGAERSFLSECEALRSVQHRNLVS 501 +LG+G +G+V G L Q +VAVK L+ Q FLSE ++ H N++ Sbjct: 587 VLGEGEFGSVMEGNLKQEDGTSQKVAVKTMKLDNFSQREIEEFLSEAACMKDFNHPNVIR 646 Query: 502 IITACSTIDSDGSAFRALIYEFMPKG 579 ++ C + S G +I FM G Sbjct: 647 LLGVCIELSSQGIPKPMVILPFMKYG 672
>ABL2_HUMAN (P42684) Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine| leukemia viral oncogene homolog 2) (Tyrosine kinase ARG) Length = 1182 Score = 43.5 bits (101), Expect = 4e-04 Identities = 27/80 (33%), Positives = 41/80 (51%) Frame = +1 Query: 340 LGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRNLVSIITACS 519 LG G YG VY G ++ L VAVK + E FL E ++ ++H NLV ++ C Sbjct: 294 LGGGQYGEVYVGVWKKYSLTVAVKTLKEDTMEVE-EFLKEAAVMKEIKHPNLVQLLGVC- 351 Query: 520 TIDSDGSAFRALIYEFMPKG 579 T++ ++ E+MP G Sbjct: 352 TLEPP----FYIVTEYMPYG 367
>CDC2_CAEEL (P34556) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 332 Score = 43.5 bits (101), Expect = 4e-04 Identities = 29/93 (31%), Positives = 49/93 (52%), Gaps = 2/93 (2%) Frame = +1 Query: 298 DLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEM--QGAERSFLSECEAL 471 D V +F++ +G+G+YG VY+GK + VA+K LE +G + + E L Sbjct: 14 DSVYTLNDFTKLEKIGEGTYGVVYKGKNRRTNAMVAMKKIRLESEDEGVPSTAVREISLL 73 Query: 472 RSVQHRNLVSIITACSTIDSDGSAFRALIYEFM 570 + +QH N+V + + I + F LI+EF+ Sbjct: 74 KELQHPNVVGLE---AVIMQENRLF--LIFEFL 101
>ABL1_CAEEL (P03949) Tyrosine-protein kinase abl-1 (EC 2.7.10.2)| Length = 1224 Score = 43.1 bits (100), Expect = 6e-04 Identities = 21/62 (33%), Positives = 32/62 (51%) Frame = +1 Query: 334 NLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRNLVSIITA 513 N LG G YG VY G +H +AVK + FL+E ++ + H+NLV ++ Sbjct: 315 NKLGGGQYGDVYEGYWKRHDCTIAVKALKEDAMPL-HEFLAEAAIMKDLHHKNLVRLLGV 373 Query: 514 CS 519 C+ Sbjct: 374 CT 375
>YR831_MIMIV (Q7T6Y2) Putative serine/threonine-protein kinase/receptor R831| precursor (EC 2.7.11.1) Length = 1624 Score = 43.1 bits (100), Expect = 6e-04 Identities = 40/147 (27%), Positives = 62/147 (42%), Gaps = 5/147 (3%) Frame = +1 Query: 154 LIRVLIPL---FGFMSLVLLVYFLVLERKMRRTRYESEAPLGEHFPKVSYNDLVEATKNF 324 ++ +IP+ FG + L LL+ + L + T + E E Sbjct: 743 ILATVIPIACIFGLLLLTLLIVIIFLLKHRNTTNNDWEIDFSE----------------L 786 Query: 325 SESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLE--MQGAERSFLSECEALRSVQHRNLV 498 LG G YG VY K + EVAVK+ + + + ERSF E + + S++H N+V Sbjct: 787 EIGETLGTGGYGEVY--KSIWKGTEVAVKLISSKHVSKDMERSFFEEVKIMTSLRHPNVV 844 Query: 499 SIITACSTIDSDGSAFRALIYEFMPKG 579 + A S S ++ EFM G Sbjct: 845 LFMAA-----STKSPNMCIVMEFMSLG 866
>PCTK1_MOUSE (Q04735) Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 1) (CRK5) Length = 496 Score = 42.4 bits (98), Expect = 0.001 Identities = 30/109 (27%), Positives = 56/109 (51%), Gaps = 2/109 (1%) Frame = +1 Query: 256 EAPLGEHFPKVSYNDL-VEATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLE-M 429 + PL +VS +++ + + + + LG+G+Y TVY+GK VA+K LE Sbjct: 142 DKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHE 201 Query: 430 QGAERSFLSECEALRSVQHRNLVSIITACSTIDSDGSAFRALIYEFMPK 576 +GA + + E L+ ++H N+V++ T S L++E++ K Sbjct: 202 EGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKS-----LTLVFEYLDK 245
>PCTK1_HUMAN (Q00536) Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 1) Length = 496 Score = 42.4 bits (98), Expect = 0.001 Identities = 30/109 (27%), Positives = 56/109 (51%), Gaps = 2/109 (1%) Frame = +1 Query: 256 EAPLGEHFPKVSYNDL-VEATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLE-M 429 + PL +VS +++ + + + + LG+G+Y TVY+GK VA+K LE Sbjct: 142 DKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHE 201 Query: 430 QGAERSFLSECEALRSVQHRNLVSIITACSTIDSDGSAFRALIYEFMPK 576 +GA + + E L+ ++H N+V++ T S L++E++ K Sbjct: 202 EGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKS-----LTLVFEYLDK 245
>MERTK_RAT (P57097) Proto-oncogene tyrosine-protein kinase MER precursor (EC| 2.7.10.1) (C-mer) (Receptor tyrosine kinase MerTK) Length = 994 Score = 42.0 bits (97), Expect = 0.001 Identities = 26/86 (30%), Positives = 40/86 (46%), Gaps = 5/86 (5%) Frame = +1 Query: 337 LLGKGSYGTVYRGKLVQH---KLEVAVKVFNLEMQGAER--SFLSECEALRSVQHRNLVS 501 +LG+G +G+V G L Q +VAVK L+ FLSE ++ H N++ Sbjct: 587 VLGEGEFGSVMEGNLKQEDGTSQKVAVKTMKLDNFSLREIEEFLSEAACMKDFNHPNVIR 646 Query: 502 IITACSTIDSDGSAFRALIYEFMPKG 579 ++ C + S G +I FM G Sbjct: 647 LLGVCIELSSQGIPKPMVILPFMKYG 672
>CDC22_ORYSA (P29619) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| Length = 292 Score = 41.6 bits (96), Expect = 0.002 Identities = 20/65 (30%), Positives = 36/65 (55%), Gaps = 2/65 (3%) Frame = +1 Query: 316 KNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEM--QGAERSFLSECEALRSVQHR 489 + + + +G+G+YG VY+GK +A+K LE +G + + E L+ +QHR Sbjct: 2 EQYEKVEKIGEGTYGVVYKGKHRHTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHR 61 Query: 490 NLVSI 504 N+V + Sbjct: 62 NIVRL 66
>PHO85_YARLI (Q6C7U8) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 294 Score = 41.6 bits (96), Expect = 0.002 Identities = 24/92 (26%), Positives = 47/92 (51%), Gaps = 1/92 (1%) Frame = +1 Query: 304 VEATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEM-QGAERSFLSECEALRSV 480 + + F + LG+G+Y TVY+G+ VA+K NL+ +G + + E ++ + Sbjct: 1 MNTSSQFQQLEKLGEGTYATVYKGRNRTTGQLVALKEINLDSEEGTPSTAIREISLMKEL 60 Query: 481 QHRNLVSIITACSTIDSDGSAFRALIYEFMPK 576 +H N+V++ T + L++E+M K Sbjct: 61 KHENIVTLYDVIHTENK-----LNLVFEYMDK 87
>CC2H1_TRYCO (P54664) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| Length = 301 Score = 41.2 bits (95), Expect = 0.002 Identities = 20/61 (32%), Positives = 35/61 (57%), Gaps = 2/61 (3%) Frame = +1 Query: 340 LGKGSYGTVYRGKLVQHKLEVAVKVFNLEM--QGAERSFLSECEALRSVQHRNLVSIITA 513 +G+GSYG VYR + + + VA+K LE +G + + E L+ ++H N+V ++ Sbjct: 11 IGEGSYGVVYRARDITTDVIVALKRIRLESVEEGVPCTAIREISILKELRHENIVRLLDV 70 Query: 514 C 516 C Sbjct: 71 C 71
>TBK1_XENLA (Q6DFJ6) Serine/threonine-protein kinase TBK1 (EC 2.7.11.1)| Length = 725 Score = 41.2 bits (95), Expect = 0.002 Identities = 27/82 (32%), Positives = 43/82 (52%), Gaps = 1/82 (1%) Frame = +1 Query: 331 SNLLGKGSYGTVYRGKLVQHKLEVAVKVFN-LEMQGAERSFLSECEALRSVQHRNLVSII 507 S++LG+G+ VYRG+ + AVKVFN L Q + E E L+ + H+N+V + Sbjct: 12 SDILGQGATANVYRGRNKKTGDLYAVKVFNSLSFQRPADVQMREFEVLKKLNHKNIVKLF 71 Query: 508 TACSTIDSDGSAFRALIYEFMP 573 + + S + L+ EF P Sbjct: 72 ---AIEEEMSSRHKVLVMEFCP 90
>PCTK1_RAT (Q63686) Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 1) Length = 496 Score = 41.2 bits (95), Expect = 0.002 Identities = 30/109 (27%), Positives = 55/109 (50%), Gaps = 2/109 (1%) Frame = +1 Query: 256 EAPLGEHFPKVSYNDL-VEATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLE-M 429 + PL VS +++ + + + + LG+G+Y TVY+GK VA+K LE Sbjct: 142 DKPLSRRLRPVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHE 201 Query: 430 QGAERSFLSECEALRSVQHRNLVSIITACSTIDSDGSAFRALIYEFMPK 576 +GA + + E L+ ++H N+V++ T S L++E++ K Sbjct: 202 EGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKS-----LTLVFEYLDK 245
>ERBB4_RAT (Q62956) Receptor tyrosine-protein kinase erbB-4 precursor (EC| 2.7.10.1) Length = 1308 Score = 41.2 bits (95), Expect = 0.002 Identities = 30/87 (34%), Positives = 44/87 (50%), Gaps = 6/87 (6%) Frame = +1 Query: 337 LLGKGSYGTVYRGKLVQH----KLEVAVKVFNLEMQG--AERSFLSECEALRSVQHRNLV 498 +LG G++GTVY+G V K+ VA+K+ N E G A F+ E + SV H +LV Sbjct: 723 VLGSGAFGTVYKGIWVPEGETVKIPVAIKILN-ETTGPKANVEFMDEALIMASVDHPHLV 781 Query: 499 SIITACSTIDSDGSAFRALIYEFMPKG 579 ++ C S L+ + MP G Sbjct: 782 RLLGVCL------SPTIQLVTQLMPHG 802
>PFTK1_MOUSE (O35495) Serine/threonine-protein kinase PFTAIRE-1 (EC 2.7.11.22)| Length = 469 Score = 40.8 bits (94), Expect = 0.003 Identities = 22/61 (36%), Positives = 36/61 (59%), Gaps = 1/61 (1%) Frame = +1 Query: 319 NFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNL-EMQGAERSFLSECEALRSVQHRNL 495 ++ + LG+GSY TVY+GK + VA+KV L E +G + + E L+ ++H N+ Sbjct: 134 SYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANI 193 Query: 496 V 498 V Sbjct: 194 V 194
>PFTK1_HUMAN (O94921) Serine/threonine-protein kinase PFTAIRE-1 (EC 2.7.11.22)| Length = 469 Score = 40.8 bits (94), Expect = 0.003 Identities = 22/61 (36%), Positives = 36/61 (59%), Gaps = 1/61 (1%) Frame = +1 Query: 319 NFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNL-EMQGAERSFLSECEALRSVQHRNL 495 ++ + LG+GSY TVY+GK + VA+KV L E +G + + E L+ ++H N+ Sbjct: 134 SYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANI 193 Query: 496 V 498 V Sbjct: 194 V 194
>IKKE_HUMAN (Q14164) Inhibitor of nuclear factor kappa-B kinase epsilon subunit| (EC 2.7.11.1) (I kappa-B kinase epsilon) (IkBKE) (IKK-epsilon) (IKK-E) (Inducible I kappa-B kinase) (IKK-i) Length = 716 Score = 40.8 bits (94), Expect = 0.003 Identities = 28/95 (29%), Positives = 50/95 (52%), Gaps = 3/95 (3%) Frame = +1 Query: 304 VEATKNF--SESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSF-LSECEALR 474 +++T N+ +LLG+G+ +VY+ + + VAVKVFN R + E E LR Sbjct: 1 MQSTANYLWHTDDLLGQGATASVYKARNKKSGELVAVKVFNTTSYLRPREVQVREFEVLR 60 Query: 475 SVQHRNLVSIITACSTIDSDGSAFRALIYEFMPKG 579 + H+N+V + + ++ GS + L+ E+ G Sbjct: 61 KLNHQNIVKLF---AVEETGGSRQKVLVMEYCSSG 92
>RYK_AVIR3 (P33497) Tyrosine-protein kinase transforming protein RYK (EC| 2.7.10.1) Length = 442 Score = 40.4 bits (93), Expect = 0.004 Identities = 27/99 (27%), Positives = 45/99 (45%), Gaps = 5/99 (5%) Frame = +1 Query: 298 DLVEATKNFSESNLLGKGSYGTVYRGKLVQHK---LEVAVKVFNLEMQGAER--SFLSEC 462 D+V S +LG+G +G+V G+L Q + +VAVK L+ FLSE Sbjct: 37 DVVIDRNALSLGKVLGEGEFGSVMEGRLSQPEGTPQKVAVKTMKLDNFSHREIEEFLSEA 96 Query: 463 EALRSVQHRNLVSIITACSTIDSDGSAFRALIYEFMPKG 579 ++ H N++ ++ C + S ++ FM G Sbjct: 97 ACIKDFDHPNVIKLLGVCIELSSQQIPKPMVVLPFMKYG 135
>CRK1_LEIME (Q06309) Cell division protein kinase 2 homolog CRK1 (EC 2.7.11.23)| Length = 301 Score = 40.4 bits (93), Expect = 0.004 Identities = 19/70 (27%), Positives = 35/70 (50%), Gaps = 2/70 (2%) Frame = +1 Query: 313 TKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNL--EMQGAERSFLSECEALRSVQH 486 T + +G+G+YG VY+ + VA+K L E +G + + E L+ ++H Sbjct: 2 TSRYERQEKIGEGTYGVVYKARDTSTAATVALKRIRLDSEEEGVPCTAIREISLLKELRH 61 Query: 487 RNLVSIITAC 516 N+V ++ C Sbjct: 62 ENIVKLLDVC 71
>PHO85_CANAL (Q9HGY5) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) (CaPHO85) Length = 326 Score = 40.4 bits (93), Expect = 0.004 Identities = 23/90 (25%), Positives = 46/90 (51%), Gaps = 1/90 (1%) Frame = +1 Query: 310 ATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEM-QGAERSFLSECEALRSVQH 486 ++ F + LG+G+Y TVY+G+ VA+K +L+ +G + + E ++ + H Sbjct: 4 SSSQFQQLEKLGEGTYATVYKGRNRATGALVALKEISLDSEEGTPSTAIREISLMKELDH 63 Query: 487 RNLVSIITACSTIDSDGSAFRALIYEFMPK 576 N+V++ T + L++E+M K Sbjct: 64 ENIVTLYDVIHTENK-----LTLVFEYMDK 88
>YSK4_HUMAN (Q56UN5) SPS1/STE20-related protein kinase YSK4 (EC 2.7.11.1)| (Regulated in COPD, protein kinase) Length = 1328 Score = 40.4 bits (93), Expect = 0.004 Identities = 27/91 (29%), Positives = 49/91 (53%), Gaps = 5/91 (5%) Frame = +1 Query: 322 FSESNLLGKGSYGTVYRGKLVQHKL----EVAVKVFN-LEMQGAERSFLSECEALRSVQH 486 +++ +LGKG+YGTVY G Q +L +VA+ N L + R E + L++++H Sbjct: 1061 WTKGEILGKGAYGTVYCGLTSQGQLIAVKQVALDTSNKLAAEKEYRKLQEEVDLLKALKH 1120 Query: 487 RNLVSIITACSTIDSDGSAFRALIYEFMPKG 579 N+V+ + C ++ ++ EF+P G Sbjct: 1121 VNIVAYLGTCLQENT-----VSIFMEFVPGG 1146
>CDC2_DICDI (P34112) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 296 Score = 40.4 bits (93), Expect = 0.004 Identities = 22/55 (40%), Positives = 30/55 (54%) Frame = +1 Query: 340 LGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRNLVSI 504 LG+G+YG VY+ K VA+K LE G + L E L+ V H N+VS+ Sbjct: 16 LGEGTYGKVYKAKEKATGRMVALKKIRLEDDGVPSTALREISLLKEVPHPNVVSL 70
>UFO_MOUSE (Q00993) Tyrosine-protein kinase receptor UFO precursor (EC| 2.7.10.1) (Adhesion-related kinase) Length = 888 Score = 40.4 bits (93), Expect = 0.004 Identities = 37/133 (27%), Positives = 58/133 (43%), Gaps = 6/133 (4%) Frame = +1 Query: 199 LLVYFLVLERKMRRTRYESEAPLG-EHFPKVSYNDLVEATKNFSESNLLGKGSYGTVYRG 375 L+V + V + RRT + LG K D++ + LG+G +G V G Sbjct: 488 LVVRYRVRKSYSRRTTEATLNSLGISEELKEKLRDVMVDRHKVALGKTLGEGEFGAVMEG 547 Query: 376 KLVQHK--LEVAVKVFNLEM--QGAERSFLSECEALRSVQHRNLVSIITAC-STIDSDGS 540 +L Q L+VAVK + + + FLSE ++ H N++ +I C D +G Sbjct: 548 QLNQDDSILKVAVKTMKIAICTRSELEDFLSEAVCMKEFDHPNVMRLIGVCFQGSDREGF 607 Query: 541 AFRALIYEFMPKG 579 +I FM G Sbjct: 608 PEPVVILPFMKHG 620
>CC2H1_TRYBB (P38973) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| Length = 301 Score = 40.0 bits (92), Expect = 0.005 Identities = 21/61 (34%), Positives = 34/61 (55%), Gaps = 2/61 (3%) Frame = +1 Query: 340 LGKGSYGTVYRGKLVQHKLEVAVKVFNLEM--QGAERSFLSECEALRSVQHRNLVSIITA 513 +G+GSYG V+R + V VAVK LE +G + + E L+ ++H N+V ++ Sbjct: 11 IGEGSYGVVFRARDVTTGTIVAVKRIRLEKEEEGVPCTAIREISILKELRHENIVRLLDV 70 Query: 514 C 516 C Sbjct: 71 C 71
>KSG2_ARATH (O23145) Shaggy-related protein kinase beta (EC 2.7.11.1)| (ASK-beta) Length = 431 Score = 40.0 bits (92), Expect = 0.005 Identities = 22/98 (22%), Positives = 50/98 (51%) Frame = +1 Query: 283 KVSYNDLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSEC 462 K ND + T ++ +++G GS+G V++ K ++ + +VA+K + + R E Sbjct: 89 KKGLNDQKDKTISYRAEHVIGTGSFGVVFQAKCLETEEKVAIKKVLQDKRYKNR----EL 144 Query: 463 EALRSVQHRNLVSIITACSTIDSDGSAFRALIYEFMPK 576 + +R + H N+V + + + + L+ E++P+ Sbjct: 145 QIMRMLDHPNVVELKHSFFSTTEKDELYLNLVLEYVPE 182
>ERBB4_HUMAN (Q15303) Receptor tyrosine-protein kinase erbB-4 precursor (EC| 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4) Length = 1308 Score = 40.0 bits (92), Expect = 0.005 Identities = 29/87 (33%), Positives = 44/87 (50%), Gaps = 6/87 (6%) Frame = +1 Query: 337 LLGKGSYGTVYRGKLVQH----KLEVAVKVFNLEMQG--AERSFLSECEALRSVQHRNLV 498 +LG G++GTVY+G V K+ VA+K+ N E G A F+ E + S+ H +LV Sbjct: 723 VLGSGAFGTVYKGIWVPEGETVKIPVAIKILN-ETTGPKANVEFMDEALIMASMDHPHLV 781 Query: 499 SIITACSTIDSDGSAFRALIYEFMPKG 579 ++ C S L+ + MP G Sbjct: 782 RLLGVCL------SPTIQLVTQLMPHG 802
>RIPK3_RAT (Q9Z2P5) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (Homocysteine respondent protein HCYP2) Length = 478 Score = 40.0 bits (92), Expect = 0.005 Identities = 22/80 (27%), Positives = 41/80 (51%) Frame = +1 Query: 340 LGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRNLVSIITACS 519 +GKG +G V+R + L+VAVK+ N + E +A+ +++H N++ ++ Sbjct: 28 VGKGGFGAVFRARHTAWNLDVAVKIVN------SKKISREVKAMVNLRHENVLLLLGVTE 81 Query: 520 TIDSDGSAFRALIYEFMPKG 579 ++ D AL+ FM G Sbjct: 82 NLEWDYVYGPALVTGFMENG 101
>SHK1_SCHPO (P50527) Serine/threonine-protein kinase pak1/shk1 (EC 2.7.11.1)| Length = 658 Score = 39.7 bits (91), Expect = 0.006 Identities = 18/56 (32%), Positives = 32/56 (57%) Frame = +1 Query: 340 LGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRNLVSII 507 +G+G+ G VY + V L VA+K N+ Q + ++E ++S H+N+V+ I Sbjct: 392 IGQGASGDVYSARQVGTNLSVAIKKMNINQQPKKEFIVNEILVMKSHHHKNIVNFI 447
>IKKE_MOUSE (Q9R0T8) Inhibitor of nuclear factor kappa-B kinase epsilon subunit| (EC 2.7.11.1) (I kappa-B kinase epsilon) (IkBKE) (IKK-epsilon) (IKK-E) (Inducible I kappa-B kinase) (IKK-i) Length = 717 Score = 39.7 bits (91), Expect = 0.006 Identities = 28/95 (29%), Positives = 50/95 (52%), Gaps = 3/95 (3%) Frame = +1 Query: 304 VEATKNF--SESNLLGKGSYGTVYRGKLVQHKLEVAVKVFN-LEMQGAERSFLSECEALR 474 +++T N+ +LLG+G+ +VY+ + + VAVKVFN + + E E LR Sbjct: 1 MQSTTNYLWHTDDLLGQGATASVYKARNKKSGEVVAVKVFNSASYRRPPEVQVREFEVLR 60 Query: 475 SVQHRNLVSIITACSTIDSDGSAFRALIYEFMPKG 579 + H+N+V + + ++ GS + LI E+ G Sbjct: 61 RLNHQNIVKLF---AVEETGGSRQKVLIMEYCSSG 92
>FES_FSVST (P00543) Tyrosine-protein kinase transforming protein Fes (EC| 2.7.10.2) Length = 477 Score = 39.7 bits (91), Expect = 0.006 Identities = 34/118 (28%), Positives = 55/118 (46%), Gaps = 5/118 (4%) Frame = +1 Query: 181 GFMSLVLLVYFLVLERKMRRTRYESEAPLGEHFPK----VSYNDLVEATKNFSESNLLGK 348 GF S+ LLV L+ R + +S L PK +++ DLV + +G+ Sbjct: 174 GFASIPLLVDHLL--RSQQPLTKKSGIVLNRAVPKDKWVLNHEDLVLGEQ-------IGR 224 Query: 349 GSYGTVYRGKLVQHKLEVAVKVFNLEM-QGAERSFLSECEALRSVQHRNLVSIITACS 519 G++G V+ G+L VAVK + + FL E + L+ H N+V +I C+ Sbjct: 225 GNFGEVFSGRLRADNTLVAVKSCRETLPPDIKAKFLQEAKILKQYSHPNIVRLIGVCT 282
>FES_FELCA (P14238) Proto-oncogene tyrosine-protein kinase FES/FPS (EC| 2.7.10.2) (C-FES) Length = 820 Score = 39.7 bits (91), Expect = 0.006 Identities = 34/118 (28%), Positives = 55/118 (46%), Gaps = 5/118 (4%) Frame = +1 Query: 181 GFMSLVLLVYFLVLERKMRRTRYESEAPLGEHFPK----VSYNDLVEATKNFSESNLLGK 348 GF S+ LLV L+ R + +S L PK +++ DLV + +G+ Sbjct: 517 GFASIPLLVDHLL--RSQQPLTKKSGIVLNRAVPKDKWVLNHEDLVLGEQ-------IGR 567 Query: 349 GSYGTVYRGKLVQHKLEVAVKVFNLEM-QGAERSFLSECEALRSVQHRNLVSIITACS 519 G++G V+ G+L VAVK + + FL E + L+ H N+V +I C+ Sbjct: 568 GNFGEVFSGRLRADNTLVAVKSCRETLPPDIKAKFLQEAKILKQYSHPNIVRLIGVCT 625
>EGFR_MOUSE (Q01279) Epidermal growth factor receptor precursor (EC 2.7.10.1)| Length = 1210 Score = 39.7 bits (91), Expect = 0.006 Identities = 42/168 (25%), Positives = 77/168 (45%), Gaps = 10/168 (5%) Frame = +1 Query: 106 PACPVASHRGTKIRYYLIRVLIPLFGFMSLVLLVYFLVLERKMRRTRYESE-----APLG 270 P+ P T I L+ +++ G + L + +V +R +RR E E P G Sbjct: 640 PSGPKIPSIATGIVGGLLFIVVVALG-IGLFMRRRHIVRKRTLRRLLQERELVEPLTPSG 698 Query: 271 EHFPKVSYNDLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQ-----G 435 E P ++ +++ T+ F + +LG G++GTVY+G + +V + V E++ Sbjct: 699 EA-PNQAHLRILKETE-FKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPK 756 Query: 436 AERSFLSECEALRSVQHRNLVSIITACSTIDSDGSAFRALIYEFMPKG 579 A + L E + SV + ++ ++ C T + LI + MP G Sbjct: 757 ANKEILDEAYVMASVDNPHVCRLLGICLT------STVQLITQLMPYG 798
>AURKC_MOUSE (O88445) Serine/threonine-protein kinase 13 (EC 2.7.11.1)| (Aurora/Ipl1/Eg2 protein 1) (Aurora-C) Length = 282 Score = 39.7 bits (91), Expect = 0.006 Identities = 21/65 (32%), Positives = 34/65 (52%), Gaps = 3/65 (4%) Frame = +1 Query: 319 NFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVF---NLEMQGAERSFLSECEALRSVQHR 489 +F LG+G +G VY +L ++ VA+KV +E +G E E E +QHR Sbjct: 15 DFEIGRPLGRGKFGRVYLARLKENHFIVALKVLFKSEIEKEGLEHQLRREVEIQAHLQHR 74 Query: 490 NLVSI 504 N++ + Sbjct: 75 NILRL 79
>ATG1_YEAST (P53104) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) (Autophagy protein 3) (Cytoplasm to vacuole targeting protein 10) Length = 897 Score = 39.7 bits (91), Expect = 0.006 Identities = 27/92 (29%), Positives = 49/92 (53%), Gaps = 4/92 (4%) Frame = +1 Query: 271 EHFPKVSYNDLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLE-VAVKVFN---LEMQGA 438 +H V++N L+ + N++ +GKGS+ TVYRG L K + VA+K + L+ + Sbjct: 8 DHTTSVNHN-LMASAGNYTAEKEIGKGSFATVYRGHLTSDKSQHVAIKEVSRAKLKNKKL 66 Query: 439 ERSFLSECEALRSVQHRNLVSIITACSTIDSD 534 + E L+ ++H ++V +I C +D Sbjct: 67 LENLEIEIAILKKIKHPHIVGLID-CERTSTD 97
>PCTK2_RAT (O35831) Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 2) Length = 523 Score = 39.7 bits (91), Expect = 0.006 Identities = 26/80 (32%), Positives = 45/80 (56%), Gaps = 1/80 (1%) Frame = +1 Query: 340 LGKGSYGTVYRGKLVQHKLEVAVKVFNLE-MQGAERSFLSECEALRSVQHRNLVSIITAC 516 LG+G+Y TVY+G+ + VA+K LE +GA + + E L+ ++H N I+T Sbjct: 198 LGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHAN---IVTLH 254 Query: 517 STIDSDGSAFRALIYEFMPK 576 + +D S L++E++ K Sbjct: 255 DIVHTDKSL--TLVFEYLDK 272
>PCTK2_MOUSE (Q8K0D0) Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 2) Length = 523 Score = 39.7 bits (91), Expect = 0.006 Identities = 26/80 (32%), Positives = 45/80 (56%), Gaps = 1/80 (1%) Frame = +1 Query: 340 LGKGSYGTVYRGKLVQHKLEVAVKVFNLE-MQGAERSFLSECEALRSVQHRNLVSIITAC 516 LG+G+Y TVY+G+ + VA+K LE +GA + + E L+ ++H N I+T Sbjct: 198 LGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHAN---IVTLH 254 Query: 517 STIDSDGSAFRALIYEFMPK 576 + +D S L++E++ K Sbjct: 255 DIVHTDKSL--TLVFEYLDK 272
>PCTK2_HUMAN (Q00537) Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 2) Length = 523 Score = 39.7 bits (91), Expect = 0.006 Identities = 26/80 (32%), Positives = 45/80 (56%), Gaps = 1/80 (1%) Frame = +1 Query: 340 LGKGSYGTVYRGKLVQHKLEVAVKVFNLE-MQGAERSFLSECEALRSVQHRNLVSIITAC 516 LG+G+Y TVY+G+ + VA+K LE +GA + + E L+ ++H N I+T Sbjct: 198 LGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHAN---IVTLH 254 Query: 517 STIDSDGSAFRALIYEFMPK 576 + +D S L++E++ K Sbjct: 255 DIVHTDKSL--TLVFEYLDK 272
>FES_FSVGA (P00542) Tyrosine-protein kinase transforming protein Fes (EC| 2.7.10.2) Length = 609 Score = 39.7 bits (91), Expect = 0.006 Identities = 34/118 (28%), Positives = 55/118 (46%), Gaps = 5/118 (4%) Frame = +1 Query: 181 GFMSLVLLVYFLVLERKMRRTRYESEAPLGEHFPK----VSYNDLVEATKNFSESNLLGK 348 GF S+ LLV L+ R + +S L PK +++ DLV + +G+ Sbjct: 306 GFASIPLLVDHLL--RSQQPLTKKSGIVLNRAVPKDKWVLNHEDLVLGEQ-------IGR 356 Query: 349 GSYGTVYRGKLVQHKLEVAVKVFNLEM-QGAERSFLSECEALRSVQHRNLVSIITACS 519 G++G V+ G+L VAVK + + FL E + L+ H N+V +I C+ Sbjct: 357 GNFGEVFSGRLRADNTLVAVKSCRETLPPDIKAKFLQEAKILKQYSHPNIVRLIGVCT 414
>ERBB_ALV (P00534) Tyrosine-protein kinase transforming protein erbB (EC| 2.7.10.1) Length = 634 Score = 39.3 bits (90), Expect = 0.008 Identities = 35/132 (26%), Positives = 63/132 (47%), Gaps = 10/132 (7%) Frame = +1 Query: 214 LVLERKMRRTRYESE-----APLGEHFPKVSYNDLVEATKNFSESNLLGKGSYGTVYRGK 378 +V +R +RR E E P GE P ++ +++ T+ F + +LG G++GTVY+G Sbjct: 93 IVRKRTLRRLLQERELVEPLTPSGEA-PNQAHLRILKETE-FKKVKVLGSGAFGTVYKGL 150 Query: 379 LVQHKLEVAVKVFNLEMQ-----GAERSFLSECEALRSVQHRNLVSIITACSTIDSDGSA 543 + +V + V E++ A + L E + SV + ++ ++ C T + Sbjct: 151 WIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLT------S 204 Query: 544 FRALIYEFMPKG 579 LI + MP G Sbjct: 205 TVQLITQLMPYG 216
>CDK2_MOUSE (P97377) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 346 Score = 39.3 bits (90), Expect = 0.008 Identities = 24/87 (27%), Positives = 45/87 (51%), Gaps = 2/87 (2%) Frame = +1 Query: 316 KNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNL--EMQGAERSFLSECEALRSVQHR 489 +NF + +G+G+YG VY+ K VA+K L E +G + + E L+ + H Sbjct: 2 ENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHP 61 Query: 490 NLVSIITACSTIDSDGSAFRALIYEFM 570 N+V ++ I ++ + L++EF+ Sbjct: 62 NIVKLL---DVIHTENKLY--LVFEFL 83
>GSK3_SCHPO (Q10452) Protein kinase gsk3 (EC 2.7.11.1) (Protein kinaae skp1)| Length = 387 Score = 39.3 bits (90), Expect = 0.008 Identities = 23/87 (26%), Positives = 47/87 (54%), Gaps = 1/87 (1%) Frame = +1 Query: 319 NFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRNLV 498 +++ S ++G GS+G V + L++ + A+K + + R E + +R ++H N+V Sbjct: 31 SYTSSKVVGSGSFGVVMQVHLIESDSKAAIKRVLQDKRFKNR----ELQIMRIMKHPNIV 86 Query: 499 SIIT-ACSTIDSDGSAFRALIYEFMPK 576 +I +T D+ + L+ EFMP+ Sbjct: 87 DLIAYYYTTGDNSDEVYLNLVLEFMPE 113
>CDK9_RAT (Q641Z4) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 372 Score = 39.3 bits (90), Expect = 0.008 Identities = 26/87 (29%), Positives = 48/87 (55%), Gaps = 2/87 (2%) Frame = +1 Query: 307 EATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVK--VFNLEMQGAERSFLSECEALRSV 480 E TK + + +G+G++G V++ K Q +VA+K + E +G + L E + L+ + Sbjct: 15 EVTK-YEKLAKIGQGTFGEVFKAKHRQTGQKVALKKVLMENEKEGFPITALREIKILQLL 73 Query: 481 QHRNLVSIITACSTIDSDGSAFRALIY 561 +H N+V++I C T S + + IY Sbjct: 74 KHENVVNLIEICRTKASPYNRCKGSIY 100
>CDK9_MOUSE (Q99J95) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 372 Score = 39.3 bits (90), Expect = 0.008 Identities = 26/87 (29%), Positives = 48/87 (55%), Gaps = 2/87 (2%) Frame = +1 Query: 307 EATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVK--VFNLEMQGAERSFLSECEALRSV 480 E TK + + +G+G++G V++ K Q +VA+K + E +G + L E + L+ + Sbjct: 15 EVTK-YEKLAKIGQGTFGEVFKAKHRQTGQKVALKKVLMENEKEGFPITALREIKILQLL 73 Query: 481 QHRNLVSIITACSTIDSDGSAFRALIY 561 +H N+V++I C T S + + IY Sbjct: 74 KHENVVNLIEICRTKASPYNRCKGSIY 100
>CDK3_HUMAN (Q00526) Cell division protein kinase 3 (EC 2.7.11.22)| Length = 305 Score = 39.3 bits (90), Expect = 0.008 Identities = 23/85 (27%), Positives = 47/85 (55%), Gaps = 2/85 (2%) Frame = +1 Query: 322 FSESNLLGKGSYGTVYRGKLVQHKLEVAVKV--FNLEMQGAERSFLSECEALRSVQHRNL 495 F + +G+G+YG VY+ K + VA+K +LEM+G + + E L+ ++H N+ Sbjct: 4 FQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKHPNI 63 Query: 496 VSIITACSTIDSDGSAFRALIYEFM 570 V ++ + ++ + L++EF+ Sbjct: 64 VRLL---DVVHNERKLY--LVFEFL 83
>CDK2_RAT (Q63699) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 39.3 bits (90), Expect = 0.008 Identities = 24/87 (27%), Positives = 45/87 (51%), Gaps = 2/87 (2%) Frame = +1 Query: 316 KNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNL--EMQGAERSFLSECEALRSVQHR 489 +NF + +G+G+YG VY+ K VA+K L E +G + + E L+ + H Sbjct: 2 ENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHP 61 Query: 490 NLVSIITACSTIDSDGSAFRALIYEFM 570 N+V ++ I ++ + L++EF+ Sbjct: 62 NIVKLL---DVIHTENKLY--LVFEFL 83
>CDK2_CRIGR (O55076) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 39.3 bits (90), Expect = 0.008 Identities = 24/87 (27%), Positives = 45/87 (51%), Gaps = 2/87 (2%) Frame = +1 Query: 316 KNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNL--EMQGAERSFLSECEALRSVQHR 489 +NF + +G+G+YG VY+ K VA+K L E +G + + E L+ + H Sbjct: 2 ENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHP 61 Query: 490 NLVSIITACSTIDSDGSAFRALIYEFM 570 N+V ++ I ++ + L++EF+ Sbjct: 62 NIVKLL---DVIHTENKLY--LVFEFL 83
>CDK2_BOVIN (Q5E9Y0) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 39.3 bits (90), Expect = 0.008 Identities = 24/87 (27%), Positives = 45/87 (51%), Gaps = 2/87 (2%) Frame = +1 Query: 316 KNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNL--EMQGAERSFLSECEALRSVQHR 489 +NF + +G+G+YG VY+ K VA+K L E +G + + E L+ + H Sbjct: 2 ENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHP 61 Query: 490 NLVSIITACSTIDSDGSAFRALIYEFM 570 N+V ++ I ++ + L++EF+ Sbjct: 62 NIVKLL---DVIHTENKLY--LVFEFL 83
>MYLK_DICDI (P25323) Myosin light chain kinase (EC 2.7.11.18) (MLCK)| Length = 295 Score = 39.3 bits (90), Expect = 0.008 Identities = 21/70 (30%), Positives = 36/70 (51%), Gaps = 2/70 (2%) Frame = +1 Query: 301 LVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGA--ERSFLSECEALR 474 + E K + LG+G++ VY G+ Q K A+KV N G E++ E + L+ Sbjct: 1 MTEVEKIYEFKEELGRGAFSIVYLGENKQTKQRYAIKVINKSELGKDYEKNLKMEVDILK 60 Query: 475 SVQHRNLVSI 504 V H N++++ Sbjct: 61 KVNHPNIIAL 70
>KOK0_YEAST (Q12236) Probable serine/threonine-protein kinase YOL100W (EC| 2.7.11.1) Length = 1081 Score = 39.3 bits (90), Expect = 0.008 Identities = 31/127 (24%), Positives = 55/127 (43%), Gaps = 7/127 (5%) Frame = +1 Query: 220 LERKMRRTRYE----SEAPLGEHFPKVSYNDLVEATKNFSESNLLGKGSYGTVYRGKLVQ 387 +E+ + + E S+ P+ + K N + + K+F +++G G+Y TV + Sbjct: 141 MEKNRNKVKIEHDSSSQKPIAKESSKAQKNIIKKGIKDFKFGSVIGDGAYSTVMLATSID 200 Query: 388 HKLEVAVKVFNLE---MQGAERSFLSECEALRSVQHRNLVSIITACSTIDSDGSAFRALI 558 K A KV N E Q + E AL+ + N S++ ST + S + + Sbjct: 201 TKKRYAAKVLNKEYLIRQKKVKYVSIEKTALQKL--NNSPSVVRLFSTFQDESSLY--FL 256 Query: 559 YEFMPKG 579 E+ P G Sbjct: 257 LEYAPNG 263
>CDK9_CAEEL (Q9TVL3) Probable cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 478 Score = 39.3 bits (90), Expect = 0.008 Identities = 30/121 (24%), Positives = 57/121 (47%), Gaps = 4/121 (3%) Frame = +1 Query: 220 LERKMRRTRYESEAPLGEHFPKVSYNDLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLE 399 LE K + + Y+ + F + +Y + + + N +G+G++G V++ + Sbjct: 58 LEVKQQLSNYQ------KLFDQATY-PFIRDVSTYEKLNKIGQGTFGEVFKARCKNTGRM 110 Query: 400 VAVK--VFNLEMQGAERSFLSECEALRSVQHRNLVSIITACS--TIDSDGSAFRALIYEF 567 VA+K + E +G + L E + L ++H N+ +I CS + + GS RA Y Sbjct: 111 VALKKILMENEKEGFPITALREVKMLEQLKHPNITDLIEVCSAKSTGTTGSKDRATFYLV 170 Query: 568 M 570 M Sbjct: 171 M 171
>CC2H3_TRYBB (P54666) Cell division control protein 2 homolog 3 (EC 2.7.11.22)| Length = 311 Score = 38.9 bits (89), Expect = 0.011 Identities = 25/85 (29%), Positives = 47/85 (55%), Gaps = 2/85 (2%) Frame = +1 Query: 322 FSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEM--QGAERSFLSECEALRSVQHRNL 495 ++ ++LG+G+YG VYR VA+K L+ +G ++ L E L+ + H N+ Sbjct: 23 YNRMDILGEGTYGVVYRAVDRATGQIVALKKVRLDRTDEGIPQTALREVSILQEIHHPNI 82 Query: 496 VSIITACSTIDSDGSAFRALIYEFM 570 V+++ I +DG + LI+E++ Sbjct: 83 VNLL---DVICADGKLY--LIFEYV 102
>ERBB_AVIER (P00535) Tyrosine-protein kinase transforming protein erbB (EC| 2.7.10.1) Length = 604 Score = 38.9 bits (89), Expect = 0.011 Identities = 34/132 (25%), Positives = 63/132 (47%), Gaps = 10/132 (7%) Frame = +1 Query: 214 LVLERKMRRTRYESE-----APLGEHFPKVSYNDLVEATKNFSESNLLGKGSYGTVYRGK 378 +V +R +RR E E P GE P ++ +++ T+ F + +LG G++GT+Y+G Sbjct: 93 IVRKRTLRRLLQERELVEPLTPSGEA-PNQAHLRILKETE-FKKVKVLGSGAFGTIYKGL 150 Query: 379 LVQHKLEVAVKVFNLEMQ-----GAERSFLSECEALRSVQHRNLVSIITACSTIDSDGSA 543 + +V + V E++ A + L E + SV + ++ ++ C T + Sbjct: 151 WIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLT------S 204 Query: 544 FRALIYEFMPKG 579 LI + MP G Sbjct: 205 TVQLITQLMPYG 216
>CDK9_CHICK (Q5ZKN1) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 372 Score = 38.9 bits (89), Expect = 0.011 Identities = 23/76 (30%), Positives = 43/76 (56%), Gaps = 2/76 (2%) Frame = +1 Query: 340 LGKGSYGTVYRGKLVQHKLEVAVK--VFNLEMQGAERSFLSECEALRSVQHRNLVSIITA 513 +G+G++G V++ K Q +VA+K + E +G + L E + L+ ++H N+V++I Sbjct: 25 IGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEI 84 Query: 514 CSTIDSDGSAFRALIY 561 C T S + + IY Sbjct: 85 CRTKASPYNRCKGSIY 100
>BUR1_YARLI (Q6C842) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 706 Score = 38.9 bits (89), Expect = 0.011 Identities = 21/97 (21%), Positives = 45/97 (46%), Gaps = 2/97 (2%) Frame = +1 Query: 289 SYNDLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVK--VFNLEMQGAERSFLSEC 462 +Y T+++ +G+G++G V+R + + K VA+K + + E +G + L E Sbjct: 27 TYYGCSNVTESYKPLGKIGEGTFGEVFRAEQITTKRHVALKKILLHSEKEGFPVTALREI 86 Query: 463 EALRSVQHRNLVSIITACSTIDSDGSAFRALIYEFMP 573 L+ ++H N++ ++ R +Y P Sbjct: 87 RILKLLRHENVIPLVDLAVERGDQSKKERGCVYMVTP 123
>PHO85_YEAST (P17157) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 305 Score = 38.9 bits (89), Expect = 0.011 Identities = 23/90 (25%), Positives = 44/90 (48%), Gaps = 1/90 (1%) Frame = +1 Query: 304 VEATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEM-QGAERSFLSECEALRSV 480 + ++ F + LG G+Y TVY+G + VA+K L+ +G + + E ++ + Sbjct: 1 MSSSSQFKQLEKLGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKEL 60 Query: 481 QHRNLVSIITACSTIDSDGSAFRALIYEFM 570 +H N+V + T + L++EFM Sbjct: 61 KHENIVRLYDVIHTENK-----LTLVFEFM 85
>CDK2_XENLA (P23437) Cell division protein kinase 2 (EC 2.7.11.22) (CDC2| homolog Eg1 protein kinase) Length = 297 Score = 38.9 bits (89), Expect = 0.011 Identities = 23/87 (26%), Positives = 46/87 (52%), Gaps = 2/87 (2%) Frame = +1 Query: 316 KNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNL--EMQGAERSFLSECEALRSVQHR 489 +NF + +G+G+YG VY+ + + VA+K L E +G + + E L+ + H Sbjct: 2 ENFQKVEKIGEGTYGVVYKARNRETGEIVALKKIRLDTETEGVPSTAIREISLLKELNHP 61 Query: 490 NLVSIITACSTIDSDGSAFRALIYEFM 570 N+V ++ I ++ + L++EF+ Sbjct: 62 NIVKLL---DVIHTENKLY--LVFEFL 83
>BTKL_DROME (P08630) Tyrosine-protein kinase Btk29A (EC 2.7.10.2) (Dsrc28C)| Length = 786 Score = 38.9 bits (89), Expect = 0.011 Identities = 22/60 (36%), Positives = 33/60 (55%) Frame = +1 Query: 340 LGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRNLVSIITACS 519 LG G +G V RGK + ++ AVK+ E +E F+ E + + +QH NLV + CS Sbjct: 532 LGSGQFGVVRRGKW-RGSIDTAVKMMK-EGTMSEDDFIEEAKVMTKLQHPNLVQLYGVCS 589
>PHO85_ASHGO (Q751E8) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 303 Score = 38.9 bits (89), Expect = 0.011 Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 1/84 (1%) Frame = +1 Query: 322 FSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEM-QGAERSFLSECEALRSVQHRNLV 498 F + LG G+Y TVY+G L VA+K L+ +G + + E ++ ++H N+V Sbjct: 9 FKQLERLGNGTYATVYKGLNKTTGLYVALKEVKLDSEEGTPSTAIREISLMKELKHENIV 68 Query: 499 SIITACSTIDSDGSAFRALIYEFM 570 + T + L++EFM Sbjct: 69 RLYDVIHTENK-----LTLVFEFM 87
>CDC2C_DROME (P23573) Cell division control protein 2 cognate (EC 2.7.11.22) (EC| 2.7.11.23) Length = 314 Score = 38.9 bits (89), Expect = 0.011 Identities = 19/64 (29%), Positives = 36/64 (56%), Gaps = 2/64 (3%) Frame = +1 Query: 319 NFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNL--EMQGAERSFLSECEALRSVQHRN 492 NF + +G+G+YG VY+ + +VA+K L E +G + + E L++++H N Sbjct: 7 NFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPN 66 Query: 493 LVSI 504 +V + Sbjct: 67 VVQL 70
>NAK1_SCHPO (O75011) Serine/threonine-protein kinase nak1 (EC 2.7.11.1) (N-rich| kinase 1) Length = 652 Score = 38.9 bits (89), Expect = 0.011 Identities = 23/67 (34%), Positives = 38/67 (56%), Gaps = 1/67 (1%) Frame = +1 Query: 310 ATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFL-SECEALRSVQH 486 A+ +++ L+G+GSYG VYRG K VA+K+ NL+ E S + E L ++ Sbjct: 6 ASSPYTKLELVGRGSYGAVYRGICNLTKETVAIKILNLDTDEDEVSDIQKEVAVLSELKQ 65 Query: 487 RNLVSII 507 ++ +II Sbjct: 66 SDVENII 72
>CDK10_HUMAN (Q15131) Cell division protein kinase 10 (EC 2.7.11.22)| (Serine/threonine-protein kinase PISSLRE) Length = 360 Score = 38.5 bits (88), Expect = 0.014 Identities = 23/67 (34%), Positives = 35/67 (52%), Gaps = 2/67 (2%) Frame = +1 Query: 310 ATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNL--EMQGAERSFLSECEALRSVQ 483 + K F + N +G+G+YG VYR + Q VA+K + E G S L E L ++ Sbjct: 35 SVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLR 94 Query: 484 HRNLVSI 504 H N+V + Sbjct: 95 HPNIVEL 101
>PAK1_HUMAN (Q13153) Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1)| (p21-activated kinase 1) (PAK-1) (P65-PAK) (Alpha-PAK) Length = 545 Score = 38.5 bits (88), Expect = 0.014 Identities = 25/95 (26%), Positives = 47/95 (49%) Frame = +1 Query: 223 ERKMRRTRYESEAPLGEHFPKVSYNDLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEV 402 E++ ++ + E L + VS D K ++ +G+G+ GTVY V EV Sbjct: 240 EKQKKKPKMSDEEILEKLRSIVSVGD---PKKKYTRFEKIGQGASGTVYTAMDVATGQEV 296 Query: 403 AVKVFNLEMQGAERSFLSECEALRSVQHRNLVSII 507 A+K NL+ Q + ++E +R ++ N+V+ + Sbjct: 297 AIKQMNLQQQPKKELIINEILVMRENKNPNIVNYL 331
>CDC22_XENLA (P24033) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| (EC 2.7.11.23) (p34 protein kinase 2) Length = 302 Score = 38.5 bits (88), Expect = 0.014 Identities = 24/85 (28%), Positives = 45/85 (52%), Gaps = 2/85 (2%) Frame = +1 Query: 322 FSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNL--EMQGAERSFLSECEALRSVQHRNL 495 +++ +G+G+YG VY+G+ VA+K L E +G + + E L+ +QH N+ Sbjct: 4 YTKIEKIGEGTYGVVYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKELQHPNI 63 Query: 496 VSIITACSTIDSDGSAFRALIYEFM 570 V ++ + D + LI+EF+ Sbjct: 64 VCLL---DVLMQDSRLY--LIFEFL 83
>CDC21_XENLA (P35567) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (p34 protein kinase 1) Length = 302 Score = 38.5 bits (88), Expect = 0.014 Identities = 24/85 (28%), Positives = 45/85 (52%), Gaps = 2/85 (2%) Frame = +1 Query: 322 FSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNL--EMQGAERSFLSECEALRSVQHRNL 495 +++ +G+G+YG VY+G+ VA+K L E +G + + E L+ +QH N+ Sbjct: 4 YTKIEKIGEGTYGVVYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKELQHPNI 63 Query: 496 VSIITACSTIDSDGSAFRALIYEFM 570 V ++ + D + LI+EF+ Sbjct: 64 VCLL---DVLMQDSRLY--LIFEFL 83
>MOS_DENAN (Q8AX01) Serine/threonine-protein kinase mos (EC 2.7.11.1) (Oocyte| maturation factor mos) (Fragment) Length = 194 Score = 38.5 bits (88), Expect = 0.014 Identities = 26/81 (32%), Positives = 40/81 (49%), Gaps = 3/81 (3%) Frame = +1 Query: 334 NLLGKGSYGTVYRGKLVQHKLEVAVKVFN---LEMQGAERSFLSECEALRSVQHRNLVSI 504 NLLG G +G+VY K H VAVK N + +SF +E +R + H N+V I Sbjct: 51 NLLGSGGFGSVY--KATYHGATVAVKQVNRCSKNHLASRQSFWAELNVVR-LDHNNVVRI 107 Query: 505 ITACSTIDSDGSAFRALIYEF 567 + A + + + +I E+ Sbjct: 108 VAASTCTPASQDSLGTIIMEY 128
>IRAK3_MOUSE (Q8K4B2) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 609 Score = 38.5 bits (88), Expect = 0.014 Identities = 26/102 (25%), Positives = 50/102 (49%), Gaps = 4/102 (3%) Frame = +1 Query: 286 VSYNDLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVF----NLEMQGAERSFL 453 +S+ ++E TK+F + L+G+G VYR + AVK+F ++++ + FL Sbjct: 166 ISFQSILEGTKHFHKDFLIGEGEIFEVYRVDI--RNQAYAVKLFKQEKKMQLKKHWKRFL 223 Query: 454 SECEALRSVQHRNLVSIITACSTIDSDGSAFRALIYEFMPKG 579 SE E L +H +++ + + + L+Y +M G Sbjct: 224 SELEVLLLFRHPHILELAAYFTETEK-----LCLVYPYMSNG 260
>PAK1_RAT (P35465) Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1)| (p21-activated kinase 1) (PAK-1) (P68-PAK) (Alpha-PAK) (Protein kinase MUK2) Length = 544 Score = 38.5 bits (88), Expect = 0.014 Identities = 25/95 (26%), Positives = 47/95 (49%) Frame = +1 Query: 223 ERKMRRTRYESEAPLGEHFPKVSYNDLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEV 402 E++ ++ + E L + VS D K ++ +G+G+ GTVY V EV Sbjct: 239 EKQKKKPKMSDEEILEKLRSIVSVGD---PKKKYTRFEKIGQGASGTVYTAMDVATGQEV 295 Query: 403 AVKVFNLEMQGAERSFLSECEALRSVQHRNLVSII 507 A+K NL+ Q + ++E +R ++ N+V+ + Sbjct: 296 AIKQMNLQQQPKKELIINEILVMRENKNPNIVNYL 330
>CSF1R_FELCA (P13369) Macrophage colony-stimulating factor 1 receptor precursor| (CSF-1-R) (EC 2.7.10.1) (Fms proto-oncogene) (c-fms) Length = 980 Score = 38.5 bits (88), Expect = 0.014 Identities = 35/138 (25%), Positives = 66/138 (47%), Gaps = 19/138 (13%) Frame = +1 Query: 163 VLIPLFGFMSLVLLVYFLVLERKMRRTRYESEAPLGEHFPKVSYNDLVEATK-------N 321 VL+ M+L+LL+ L+L + ++ +Y+ + E + SY ++ T+ Sbjct: 515 VLLTCMSIMALLLLLLLLLLYKYKQKPKYQVRWKIIESYEGNSYT-FIDPTQLPYNEKWE 573 Query: 322 FSESNL-----LGKGSYGTVYRGKLV-----QHKLEVAVKVFNLEMQGAER-SFLSECEA 468 F +NL LG G++G V L+VAVK+ E+ + +SE + Sbjct: 574 FPRNNLQFGKTLGAGAFGKVVEATAFGLGKEDAVLKVAVKMLKSTAHADEKEALMSELKI 633 Query: 469 LRSV-QHRNLVSIITACS 519 + + QH N+V+++ AC+ Sbjct: 634 MSHLGQHENIVNLLGACT 651
>CDK2_MESAU (P48963) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 38.5 bits (88), Expect = 0.014 Identities = 21/71 (29%), Positives = 36/71 (50%), Gaps = 2/71 (2%) Frame = +1 Query: 316 KNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNL--EMQGAERSFLSECEALRSVQHR 489 +NF + +G+G+YG VY+ K VA+K L E +G + + E L+ + H Sbjct: 2 ENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHP 61 Query: 490 NLVSIITACST 522 N+V ++ T Sbjct: 62 NIVKLLDVIHT 72
>MET_PONPY (Q2IBD8) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 38.5 bits (88), Expect = 0.014 Identities = 25/81 (30%), Positives = 43/81 (53%), Gaps = 4/81 (4%) Frame = +1 Query: 331 SNLLGKGSYGTVYRGKLVQH---KLEVAVKVFN-LEMQGAERSFLSECEALRSVQHRNLV 498 + ++G+G +G VY G L+ + K+ AVK N + G FL+E ++ H N++ Sbjct: 1081 NEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVL 1140 Query: 499 SIITACSTIDSDGSAFRALIY 561 S++ C + S+GS L Y Sbjct: 1141 SLLGIC--LRSEGSPLVVLPY 1159
>MET_PANTR (Q2QLF1) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 38.5 bits (88), Expect = 0.014 Identities = 25/81 (30%), Positives = 43/81 (53%), Gaps = 4/81 (4%) Frame = +1 Query: 331 SNLLGKGSYGTVYRGKLVQH---KLEVAVKVFN-LEMQGAERSFLSECEALRSVQHRNLV 498 + ++G+G +G VY G L+ + K+ AVK N + G FL+E ++ H N++ Sbjct: 1081 NEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVL 1140 Query: 499 SIITACSTIDSDGSAFRALIY 561 S++ C + S+GS L Y Sbjct: 1141 SLLGIC--LRSEGSPLVVLPY 1159
>MET_HUMAN (P08581) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 38.5 bits (88), Expect = 0.014 Identities = 25/81 (30%), Positives = 43/81 (53%), Gaps = 4/81 (4%) Frame = +1 Query: 331 SNLLGKGSYGTVYRGKLVQH---KLEVAVKVFN-LEMQGAERSFLSECEALRSVQHRNLV 498 + ++G+G +G VY G L+ + K+ AVK N + G FL+E ++ H N++ Sbjct: 1081 NEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVL 1140 Query: 499 SIITACSTIDSDGSAFRALIY 561 S++ C + S+GS L Y Sbjct: 1141 SLLGIC--LRSEGSPLVVLPY 1159
>KFMS_FSVMD (P00545) Tyrosine-protein kinase transforming protein fms (EC| 2.7.10.1) Length = 978 Score = 38.5 bits (88), Expect = 0.014 Identities = 35/138 (25%), Positives = 67/138 (48%), Gaps = 19/138 (13%) Frame = +1 Query: 163 VLIPLFGFMSLVLLVYFLVLERKMRRTRYESEAPLGEHFPKVSYNDLVEATK-------N 321 VL+ M+L+LL+ L+L + ++ +Y+ + E + SY ++ T+ Sbjct: 549 VLLTCMSIMALLLLLLLLLLYKYKQKPKYQVRWKIIESYEGNSYT-FIDPTQLPYNEKWE 607 Query: 322 FSESNLLGKGSYGTVYRGKLVQHK----------LEVAVKVFNLEMQGAER-SFLSECEA 468 F +NL + GT GK+V+ L+VAVK+ E+ + +SE + Sbjct: 608 FPRNNLQFGKTLGTGAFGKVVEATAFGLGKEDAVLKVAVKMLKSTAHADEKEALMSELKI 667 Query: 469 LRSV-QHRNLVSIITACS 519 + + QH N+V+++ AC+ Sbjct: 668 MSHLGQHENIVNLLGACT 685
>JAK_DROME (Q24592) Tyrosine-protein kinase hopscotch (EC 2.7.10.2)| Length = 1177 Score = 38.5 bits (88), Expect = 0.014 Identities = 23/64 (35%), Positives = 37/64 (57%), Gaps = 5/64 (7%) Frame = +1 Query: 322 FSESNLLGKGSYGTVYRGKLV-----QHKLEVAVKVFNLEMQGAERSFLSECEALRSVQH 486 ++ N++G+G YGTVY+G L Q + +VA+K+ N MQ F E +R++ H Sbjct: 892 YNMENMIGRGHYGTVYKGHLEFNDKDQPREQVAIKMLN-TMQ-VSTDFHREIGIMRTLSH 949 Query: 487 RNLV 498 N+V Sbjct: 950 PNIV 953
>PCTK3_PONPY (Q5RD01) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 472 Score = 38.5 bits (88), Expect = 0.014 Identities = 30/117 (25%), Positives = 61/117 (52%), Gaps = 2/117 (1%) Frame = +1 Query: 226 RKMRRTRYESEAPLGEHFPKVSYNDL-VEATKNFSESNLLGKGSYGTVYRGKLVQHKLEV 402 +K++ + PL + S +D+ + + + + LG+G+Y TV++G+ + V Sbjct: 109 QKLQMESPDLPKPLSRMSRRASLSDIGFGKLETYVKLDKLGEGTYATVFKGRSKLTENLV 168 Query: 403 AVKVFNLE-MQGAERSFLSECEALRSVQHRNLVSIITACSTIDSDGSAFRALIYEFM 570 A+K LE +GA + + E L++++H N I+T I +D S L++E++ Sbjct: 169 ALKEIRLEHEEGAPCTAIREVSLLKNLKHAN---IVTLHDLIHTDRSL--TLVFEYL 220
>PCTK3_HUMAN (Q07002) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 472 Score = 38.5 bits (88), Expect = 0.014 Identities = 30/117 (25%), Positives = 61/117 (52%), Gaps = 2/117 (1%) Frame = +1 Query: 226 RKMRRTRYESEAPLGEHFPKVSYNDL-VEATKNFSESNLLGKGSYGTVYRGKLVQHKLEV 402 +K++ + PL + S +D+ + + + + LG+G+Y TV++G+ + V Sbjct: 109 QKLQMESPDLPKPLSRMSRRASLSDIGFGKLETYVKLDKLGEGTYATVFKGRSKLMENLV 168 Query: 403 AVKVFNLE-MQGAERSFLSECEALRSVQHRNLVSIITACSTIDSDGSAFRALIYEFM 570 A+K LE +GA + + E L++++H N I+T I +D S L++E++ Sbjct: 169 ALKEIRLEHEEGAPCTAIREVSLLKNLKHAN---IVTLHDLIHTDRSL--TLVFEYL 220
>FES_MOUSE (P16879) Proto-oncogene tyrosine-protein kinase Fes/Fps (EC| 2.7.10.2) (C-Fes) Length = 820 Score = 38.5 bits (88), Expect = 0.014 Identities = 36/135 (26%), Positives = 62/135 (45%), Gaps = 10/135 (7%) Frame = +1 Query: 145 RYYLIRVLIPLF-----GFMSLVLLVYFLVLERKMRRTRYESEAPLGEHFPK----VSYN 297 R+++I+ L L+ GF S+ LL+ L+ ++ + S L PK + + Sbjct: 500 RHFIIQSLDNLYRLEGDGFPSIPLLITHLLSSQQPLTKK--SGVVLFRAVPKDKWVLKHE 557 Query: 298 DLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEM-QGAERSFLSECEALR 474 DLV + +G+G++G V+ G+L VAVK + + FL E L+ Sbjct: 558 DLVLGEQ-------IGRGNFGEVFSGRLRADNTPVAVKSCRETLPPDLKAKFLQEARILK 610 Query: 475 SVQHRNLVSIITACS 519 H N+V +I C+ Sbjct: 611 QYNHPNIVRLIGVCT 625
>MET_PIG (Q2QLE0) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 38.5 bits (88), Expect = 0.014 Identities = 25/81 (30%), Positives = 43/81 (53%), Gaps = 4/81 (4%) Frame = +1 Query: 331 SNLLGKGSYGTVYRGKLVQH---KLEVAVKVFN-LEMQGAERSFLSECEALRSVQHRNLV 498 + ++G+G +G VY G L+ + K+ AVK N + G FL+E ++ H N++ Sbjct: 1081 NEVIGRGHFGCVYHGTLLDNDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVL 1140 Query: 499 SIITACSTIDSDGSAFRALIY 561 S++ C + S+GS L Y Sbjct: 1141 SLLGIC--LRSEGSPLVVLPY 1159
>MET_HORSE (Q2QLA9) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 38.5 bits (88), Expect = 0.014 Identities = 25/81 (30%), Positives = 43/81 (53%), Gaps = 4/81 (4%) Frame = +1 Query: 331 SNLLGKGSYGTVYRGKLVQH---KLEVAVKVFN-LEMQGAERSFLSECEALRSVQHRNLV 498 + ++G+G +G VY G L+ + K+ AVK N + G FL+E ++ H N++ Sbjct: 1081 NEVIGRGHFGCVYHGTLLDNDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVL 1140 Query: 499 SIITACSTIDSDGSAFRALIY 561 S++ C + S+GS L Y Sbjct: 1141 SLLGIC--LRSEGSPLVVLPY 1159
>MET_CALMO (Q2QLC0) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 38.5 bits (88), Expect = 0.014 Identities = 25/81 (30%), Positives = 43/81 (53%), Gaps = 4/81 (4%) Frame = +1 Query: 331 SNLLGKGSYGTVYRGKLVQH---KLEVAVKVFN-LEMQGAERSFLSECEALRSVQHRNLV 498 + ++G+G +G VY G L+ + K+ AVK N + G FL+E ++ H N++ Sbjct: 1081 NEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVL 1140 Query: 499 SIITACSTIDSDGSAFRALIY 561 S++ C + S+GS L Y Sbjct: 1141 SLLGIC--LRSEGSPLVVLPY 1159
>MET_CALJA (Q2QLG5) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 38.5 bits (88), Expect = 0.014 Identities = 25/81 (30%), Positives = 43/81 (53%), Gaps = 4/81 (4%) Frame = +1 Query: 331 SNLLGKGSYGTVYRGKLVQH---KLEVAVKVFN-LEMQGAERSFLSECEALRSVQHRNLV 498 + ++G+G +G VY G L+ + K+ AVK N + G FL+E ++ H N++ Sbjct: 1081 NEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVL 1140 Query: 499 SIITACSTIDSDGSAFRALIY 561 S++ C + S+GS L Y Sbjct: 1141 SLLGIC--LRSEGSPLVVLPY 1159
>UFO_HUMAN (P30530) Tyrosine-protein kinase receptor UFO precursor (EC| 2.7.10.1) (AXL oncogene) Length = 887 Score = 38.5 bits (88), Expect = 0.014 Identities = 38/134 (28%), Positives = 60/134 (44%), Gaps = 7/134 (5%) Frame = +1 Query: 199 LLVYFLVLERKMRRTRYESEAPLG-EHFPKVSYNDLVEATKNFSESNLLGKGSYGTVYRG 375 L+V + V + RRT + LG K D++ + LG+G +G V G Sbjct: 487 LVVRYRVRKSYSRRTTEATLNSLGISEELKEKLRDVMVDRHKVALGKTLGEGEFGAVMEG 546 Query: 376 KLVQHK--LEVAVKVFNLEM--QGAERSFLSECEALRSVQHRNLVSIITACSTIDSDGSA 543 +L Q L+VAVK + + + FLSE ++ H N++ +I C S+ + Sbjct: 547 QLNQDDSILKVAVKTMKIAICTRSELEDFLSEAVCMKEFDHPNVMRLIGVCFQ-GSERES 605 Query: 544 FRA--LIYEFMPKG 579 F A +I FM G Sbjct: 606 FPAPVVILPFMKHG 619
>MET_OTOGA (Q2QLH6) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 38.5 bits (88), Expect = 0.014 Identities = 25/81 (30%), Positives = 43/81 (53%), Gaps = 4/81 (4%) Frame = +1 Query: 331 SNLLGKGSYGTVYRGKLVQH---KLEVAVKVFN-LEMQGAERSFLSECEALRSVQHRNLV 498 + ++G+G +G VY G L+ + K+ AVK N + G FL+E ++ H N++ Sbjct: 1082 NEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVL 1141 Query: 499 SIITACSTIDSDGSAFRALIY 561 S++ C + S+GS L Y Sbjct: 1142 SLLGIC--LRSEGSPLVVLPY 1160
>MET_MICMU (Q2QL89) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 38.5 bits (88), Expect = 0.014 Identities = 25/81 (30%), Positives = 43/81 (53%), Gaps = 4/81 (4%) Frame = +1 Query: 331 SNLLGKGSYGTVYRGKLVQH---KLEVAVKVFN-LEMQGAERSFLSECEALRSVQHRNLV 498 + ++G+G +G VY G L+ + K+ AVK N + G FL+E ++ H N++ Sbjct: 1082 NEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVL 1141 Query: 499 SIITACSTIDSDGSAFRALIY 561 S++ C + S+GS L Y Sbjct: 1142 SLLGIC--LRSEGSPLVVLPY 1160
>MET_CANFA (Q75ZY9) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 38.5 bits (88), Expect = 0.014 Identities = 25/81 (30%), Positives = 43/81 (53%), Gaps = 4/81 (4%) Frame = +1 Query: 331 SNLLGKGSYGTVYRGKLVQH---KLEVAVKVFN-LEMQGAERSFLSECEALRSVQHRNLV 498 + ++G+G +G VY G L+ + K+ AVK N + G FL+E ++ H N++ Sbjct: 1082 NEVIGRGHFGCVYHGTLLDNDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVL 1141 Query: 499 SIITACSTIDSDGSAFRALIY 561 S++ C + S+GS L Y Sbjct: 1142 SLLGIC--LRSEGSPLVVLPY 1160
>KSR2_HUMAN (Q6VAB6) Kinase suppressor of ras-2 (hKSR2)| Length = 829 Score = 38.5 bits (88), Expect = 0.014 Identities = 21/62 (33%), Positives = 35/62 (56%), Gaps = 2/62 (3%) Frame = +1 Query: 337 LLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAE--RSFLSECEALRSVQHRNLVSIIT 510 L+GKG +G VY G+ EVA+++ ++E + ++F E A R +H N+V + Sbjct: 550 LIGKGRFGQVYHGR---WHGEVAIRLIDIERDNEDQLKAFKREVMAYRQTRHENVVLFMG 606 Query: 511 AC 516 AC Sbjct: 607 AC 608
>ERBB_AVIEU (P11273) Tyrosine-protein kinase transforming protein erbB (EC| 2.7.10.1) Length = 540 Score = 38.5 bits (88), Expect = 0.014 Identities = 35/132 (26%), Positives = 63/132 (47%), Gaps = 10/132 (7%) Frame = +1 Query: 214 LVLERKMRRTRYESE-----APLGEHFPKVSYNDLVEATKNFSESNLLGKGSYGTVYRGK 378 +V +R +RR E E P GE P ++ +++ T+ F + +LG G++GTVY+G Sbjct: 93 IVRKRTLRRLLQERELVEPLTPSGEA-PNQAHLRILKETE-FKKVKVLGFGAFGTVYKGL 150 Query: 379 LVQHKLEVAVKVFNLEMQ-----GAERSFLSECEALRSVQHRNLVSIITACSTIDSDGSA 543 + +V + V E++ A + L E + SV + ++ ++ C T + Sbjct: 151 WIPEGEKVTIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLT------S 204 Query: 544 FRALIYEFMPKG 579 LI + MP G Sbjct: 205 TVQLITQLMPYG 216
>XMRK_XIPMA (P13388) Melanoma receptor tyrosine-protein kinase precursor (EC| 2.7.10.1) Length = 1167 Score = 38.1 bits (87), Expect = 0.018 Identities = 37/145 (25%), Positives = 67/145 (46%), Gaps = 16/145 (11%) Frame = +1 Query: 193 LVLLVYFLVLERKMRRTR-----------YESEAPLGEHFPKVSYNDLVEATKNFSESNL 339 + LL+ L+ R+++R R E P G+ P ++ +++ T+ F + + Sbjct: 658 VALLIVVLLRRRRIKRKRTIRCLLQEKELVEPLTPSGQA-PNQAFLRILKETE-FKKDRV 715 Query: 340 LGKGSYGTVYRGKL----VQHKLEVAVKVF-NLEMQGAERSFLSECEALRSVQHRNLVSI 504 LG G++GTVY+G ++ VA+KV + L E + SV H ++ + Sbjct: 716 LGSGAFGTVYKGLWNPDGENIRIPVAIKVLREATSPKVNQEVLDEAYVMASVDHPHVCRL 775 Query: 505 ITACSTIDSDGSAFRALIYEFMPKG 579 + C T SA + L+ + MP G Sbjct: 776 LGICLT-----SAVQ-LVTQLMPYG 794
>EGFR_HUMAN (P00533) Epidermal growth factor receptor precursor (EC 2.7.10.1)| (Receptor tyrosine-protein kinase ErbB-1) Length = 1210 Score = 38.1 bits (87), Expect = 0.018 Identities = 39/152 (25%), Positives = 71/152 (46%), Gaps = 10/152 (6%) Frame = +1 Query: 154 LIRVLIPLFGFMSLVLLVYFLVLERKMRRTRYESE-----APLGEHFPKVSYNDLVEATK 318 L+ +L+ G + L + +V +R +RR E E P GE P + +++ T+ Sbjct: 654 LLLLLVVALG-IGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEA-PNQALLRILKETE 711 Query: 319 NFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQ-----GAERSFLSECEALRSVQ 483 F + +LG G++GTVY+G + +V + V E++ A + L E + SV Sbjct: 712 -FKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVD 770 Query: 484 HRNLVSIITACSTIDSDGSAFRALIYEFMPKG 579 + ++ ++ C T + LI + MP G Sbjct: 771 NPHVCRLLGICLT------STVQLITQLMPFG 796
>ABL_DROME (P00522) Tyrosine-protein kinase Abl (EC 2.7.10.2) (Abelson| protein) (D-ash) Length = 1620 Score = 38.1 bits (87), Expect = 0.018 Identities = 22/60 (36%), Positives = 31/60 (51%) Frame = +1 Query: 340 LGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRNLVSIITACS 519 LG G YG VY ++ VAVK E A + FL E ++ ++H NLV +I C+ Sbjct: 377 LGGGQYGEVYEAVWKRYGNTVAVKTLK-EDTMALKDFLEEAAIMKEMKHPNLVQLIGVCT 435
>PAK1_MOUSE (O88643) Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1)| (p21-activated kinase 1) (PAK-1) (P65-PAK) (Alpha-PAK) (CDC42/RAC effector kinase PAK-A) Length = 545 Score = 38.1 bits (87), Expect = 0.018 Identities = 25/95 (26%), Positives = 47/95 (49%) Frame = +1 Query: 223 ERKMRRTRYESEAPLGEHFPKVSYNDLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEV 402 E++ ++ + E L + VS D K ++ +G+G+ GTVY V EV Sbjct: 240 EKQKKKPKMSDEEILEKLRSIVSVGD---PKKKYTPFEKIGQGASGTVYTAMDVATGQEV 296 Query: 403 AVKVFNLEMQGAERSFLSECEALRSVQHRNLVSII 507 A+K NL+ Q + ++E +R ++ N+V+ + Sbjct: 297 AIKQMNLQQQPKKELIINEILVMRENKNPNIVNYL 331
>CDC2_HUMAN (P06493) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 38.1 bits (87), Expect = 0.018 Identities = 19/65 (29%), Positives = 38/65 (58%), Gaps = 2/65 (3%) Frame = +1 Query: 316 KNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEM--QGAERSFLSECEALRSVQHR 489 +++++ +G+G+YG VY+G+ VA+K LE +G + + E L+ ++H Sbjct: 2 EDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHP 61 Query: 490 NLVSI 504 N+VS+ Sbjct: 62 NIVSL 66
>CDC2_BOVIN (P48734) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 38.1 bits (87), Expect = 0.018 Identities = 19/65 (29%), Positives = 38/65 (58%), Gaps = 2/65 (3%) Frame = +1 Query: 316 KNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEM--QGAERSFLSECEALRSVQHR 489 +++++ +G+G+YG VY+G+ VA+K LE +G + + E L+ ++H Sbjct: 2 EDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHP 61 Query: 490 NLVSI 504 N+VS+ Sbjct: 62 NIVSL 66
>WNK4_RAT (Q7TPK6) Serine/threonine-protein kinase WNK4 (EC 2.7.11.1)| (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4) Length = 1222 Score = 38.1 bits (87), Expect = 0.018 Identities = 27/82 (32%), Positives = 42/82 (51%), Gaps = 2/82 (2%) Frame = +1 Query: 340 LGKGSYGTVYRGKLVQHKLEVA-VKVFNLEMQGAERS-FLSECEALRSVQHRNLVSIITA 513 +G+GS+ TVYRG +EVA ++ ++ AER F E E L+ +QH N+V + Sbjct: 177 IGRGSFKTVYRGLDTDTTVEVAWCELQTRKLSRAERQRFSEEVEMLKGLQHPNIVRFYDS 236 Query: 514 CSTIDSDGSAFRALIYEFMPKG 579 ++ G L+ E M G Sbjct: 237 WKSV-LRGQVCIVLVTELMTSG 257
>WNK4_MOUSE (Q80UE6) Serine/threonine-protein kinase WNK4 (EC 2.7.11.1)| (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4) Length = 1222 Score = 38.1 bits (87), Expect = 0.018 Identities = 27/82 (32%), Positives = 42/82 (51%), Gaps = 2/82 (2%) Frame = +1 Query: 340 LGKGSYGTVYRGKLVQHKLEVA-VKVFNLEMQGAERS-FLSECEALRSVQHRNLVSIITA 513 +G+GS+ TVYRG +EVA ++ ++ AER F E E L+ +QH N+V + Sbjct: 177 IGRGSFKTVYRGLDTDTTVEVAWCELQTRKLSRAERQRFSEEVEMLKGLQHPNIVRFYDS 236 Query: 514 CSTIDSDGSAFRALIYEFMPKG 579 ++ G L+ E M G Sbjct: 237 WKSV-LRGQVCIVLVTELMTSG 257
>FES_HUMAN (P07332) Proto-oncogene tyrosine-protein kinase Fes/Fps (EC| 2.7.10.2) (C-Fes) Length = 822 Score = 38.1 bits (87), Expect = 0.018 Identities = 38/135 (28%), Positives = 64/135 (47%), Gaps = 10/135 (7%) Frame = +1 Query: 145 RYYLIRVLIPLF-----GFMSLVLLVYFLVLERKMRRTRYESEAPLGEHFPK----VSYN 297 R+++I+ L L+ GF S+ LL+ L L + T+ +S L PK +++ Sbjct: 502 RHFIIQSLDNLYRLEGEGFPSIPLLIDHL-LSTQQPLTK-KSGVVLHRAVPKDKWVLNHE 559 Query: 298 DLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEM-QGAERSFLSECEALR 474 DLV + +G+G++G V+ G+L VAVK + + FL E L+ Sbjct: 560 DLVLGEQ-------IGRGNFGEVFSGRLRADNTLVAVKSCRETLPPDLKAKFLQEARILK 612 Query: 475 SVQHRNLVSIITACS 519 H N+V +I C+ Sbjct: 613 QYSHPNIVRLIGVCT 627
>EPB1B_XENLA (Q91736) Ephrin type-B receptor 1-B (EC 2.7.10.1) (Tyrosine-protein| kinase receptor XELK) (Fragment) Length = 902 Score = 38.1 bits (87), Expect = 0.018 Identities = 24/85 (28%), Positives = 43/85 (50%), Gaps = 13/85 (15%) Frame = +1 Query: 289 SYNDLVEATKNFSES---------NLLGKGSYGTVYRGKL-VQHKLEVAVKVFNLEMQGA 438 +Y D EA + F++ ++G G +G VY+G+L + K E++V + L+ + Sbjct: 517 TYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPSKREISVAIKTLKAGYS 576 Query: 439 E---RSFLSECEALRSVQHRNLVSI 504 E R FLSE + H N++ + Sbjct: 577 EKQRRDFLSEASIMGQFDHPNIIRL 601
>CDK2_HUMAN (P24941) Cell division protein kinase 2 (EC 2.7.11.22) (p33 protein| kinase) Length = 298 Score = 38.1 bits (87), Expect = 0.018 Identities = 23/87 (26%), Positives = 45/87 (51%), Gaps = 2/87 (2%) Frame = +1 Query: 316 KNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNL--EMQGAERSFLSECEALRSVQHR 489 +NF + +G+G+YG VY+ + VA+K L E +G + + E L+ + H Sbjct: 2 ENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHP 61 Query: 490 NLVSIITACSTIDSDGSAFRALIYEFM 570 N+V ++ I ++ + L++EF+ Sbjct: 62 NIVKLL---DVIHTENKLY--LVFEFL 83
>WNK4_HUMAN (Q96J92) Serine/threonine-protein kinase WNK4 (EC 2.7.11.1)| (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4) Length = 1243 Score = 38.1 bits (87), Expect = 0.018 Identities = 27/82 (32%), Positives = 42/82 (51%), Gaps = 2/82 (2%) Frame = +1 Query: 340 LGKGSYGTVYRGKLVQHKLEVA-VKVFNLEMQGAERS-FLSECEALRSVQHRNLVSIITA 513 +G+GS+ TVYRG +EVA ++ ++ AER F E E L+ +QH N+V + Sbjct: 180 IGRGSFKTVYRGLDTDTTVEVAWCELQTRKLSRAERQRFSEEVEMLKGLQHPNIVRFYDS 239 Query: 514 CSTIDSDGSAFRALIYEFMPKG 579 ++ G L+ E M G Sbjct: 240 WKSV-LRGQVCIVLVTELMTSG 260
>PAK3_PONPY (Q7YQL3) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) Length = 559 Score = 38.1 bits (87), Expect = 0.018 Identities = 24/95 (25%), Positives = 48/95 (50%) Frame = +1 Query: 223 ERKMRRTRYESEAPLGEHFPKVSYNDLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEV 402 +R+ ++++ E L + VS D K ++ +G+G+ GTVY + EV Sbjct: 253 DRQRKKSKMTDEEILEKLRSIVSVGD---PKKKYTRFEKIGQGASGTVYTALDIATGQEV 309 Query: 403 AVKVFNLEMQGAERSFLSECEALRSVQHRNLVSII 507 A+K NL+ Q + ++E +R ++ N+V+ + Sbjct: 310 AIKQMNLQQQPKKELIINEILVMRENKNPNIVNYL 344
>PAK3_PANTR (Q7YQL4) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) Length = 559 Score = 38.1 bits (87), Expect = 0.018 Identities = 24/95 (25%), Positives = 48/95 (50%) Frame = +1 Query: 223 ERKMRRTRYESEAPLGEHFPKVSYNDLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEV 402 +R+ ++++ E L + VS D K ++ +G+G+ GTVY + EV Sbjct: 253 DRQRKKSKMTDEEILEKLRSIVSVGD---PKKKYTRFEKIGQGASGTVYTALDIATGQEV 309 Query: 403 AVKVFNLEMQGAERSFLSECEALRSVQHRNLVSII 507 A+K NL+ Q + ++E +R ++ N+V+ + Sbjct: 310 AIKQMNLQQQPKKELIINEILVMRENKNPNIVNYL 344
>PAK3_MOUSE (Q61036) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) (Beta-PAK) (CDC42/RAC effector kinase PAK-B) Length = 559 Score = 38.1 bits (87), Expect = 0.018 Identities = 24/95 (25%), Positives = 48/95 (50%) Frame = +1 Query: 223 ERKMRRTRYESEAPLGEHFPKVSYNDLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEV 402 +R+ ++++ E L + VS D K ++ +G+G+ GTVY + EV Sbjct: 253 DRQRKKSKMTDEEILEKLRSIVSVGD---PKKKYTRFEKIGQGASGTVYTALDIATGQEV 309 Query: 403 AVKVFNLEMQGAERSFLSECEALRSVQHRNLVSII 507 A+K NL+ Q + ++E +R ++ N+V+ + Sbjct: 310 AIKQMNLQQQPKKELIINEILVMRENKNPNIVNYL 344
>PAK3_HUMAN (O75914) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) (Beta-PAK) (Oligophrenin-3) Length = 559 Score = 38.1 bits (87), Expect = 0.018 Identities = 24/95 (25%), Positives = 48/95 (50%) Frame = +1 Query: 223 ERKMRRTRYESEAPLGEHFPKVSYNDLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEV 402 +R+ ++++ E L + VS D K ++ +G+G+ GTVY + EV Sbjct: 253 DRQRKKSKMTDEEILEKLRSIVSVGD---PKKKYTRFEKIGQGASGTVYTALDIATGQEV 309 Query: 403 AVKVFNLEMQGAERSFLSECEALRSVQHRNLVSII 507 A+K NL+ Q + ++E +R ++ N+V+ + Sbjct: 310 AIKQMNLQQQPKKELIINEILVMRENKNPNIVNYL 344
>EPB1A_XENLA (Q91571) Ephrin type-B receptor 1-A precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor XEK) Length = 985 Score = 38.1 bits (87), Expect = 0.018 Identities = 24/85 (28%), Positives = 43/85 (50%), Gaps = 13/85 (15%) Frame = +1 Query: 289 SYNDLVEATKNFSES---------NLLGKGSYGTVYRGKL-VQHKLEVAVKVFNLEMQGA 438 +Y D EA + F++ ++G G +G VY+G+L + K E++V + L+ + Sbjct: 600 TYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPSKREISVAIKTLKAGYS 659 Query: 439 E---RSFLSECEALRSVQHRNLVSI 504 E R FLSE + H N++ + Sbjct: 660 EKQRRDFLSEASIMGQFDHPNIIRL 684
>PAK3_RAT (Q62829) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) (Beta-PAK) (p65-PAK) Length = 544 Score = 38.1 bits (87), Expect = 0.018 Identities = 24/95 (25%), Positives = 48/95 (50%) Frame = +1 Query: 223 ERKMRRTRYESEAPLGEHFPKVSYNDLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEV 402 +R+ ++++ E L + VS D K ++ +G+G+ GTVY + EV Sbjct: 238 DRQRKKSKMTDEEILEKLRSIVSVGD---PKKKYTRFEKIGQGASGTVYTALDIATGQEV 294 Query: 403 AVKVFNLEMQGAERSFLSECEALRSVQHRNLVSII 507 A+K NL+ Q + ++E +R ++ N+V+ + Sbjct: 295 AIKQMNLQQQPKKELIINEILVMRENKNPNIVNYL 329
>ATG1_BOTCI (Q6H9I1) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) (Botryotinia fuckeliana putative kinase exons 1-3) Length = 952 Score = 37.7 bits (86), Expect = 0.024 Identities = 22/65 (33%), Positives = 38/65 (58%), Gaps = 2/65 (3%) Frame = +1 Query: 319 NFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEM--QGAERSFLSECEALRSVQHRN 492 +F+ + +GKGS+ TVYRG + VA+K NL + + + E E L+S+ H + Sbjct: 22 SFTINEQIGKGSFATVYRGTHMPSGNLVAIKSVNLSRLNKKLKDNLYVEIEILKSLYHPH 81 Query: 493 LVSII 507 +V++I Sbjct: 82 IVALI 86
>CSF1R_HUMAN (P07333) Macrophage colony-stimulating factor 1 receptor precursor| (CSF-1-R) (EC 2.7.10.1) (Fms proto-oncogene) (c-fms) (CD115 antigen) Length = 972 Score = 37.7 bits (86), Expect = 0.024 Identities = 34/138 (24%), Positives = 66/138 (47%), Gaps = 19/138 (13%) Frame = +1 Query: 163 VLIPLFGFMSLVLLVYFLVLERKMRRTRYESEAPLGEHFPKVSYNDLVEATK-------N 321 V++ M+L+LL+ L+L + ++ +Y+ + E + SY ++ T+ Sbjct: 518 VVVACMSIMALLLLLLLLLLYKYKQKPKYQVRWKIIESYEGNSYT-FIDPTQLPYNEKWE 576 Query: 322 FSESNL-----LGKGSYGTVYRGKLV-----QHKLEVAVKVFNLEMQGAER-SFLSECEA 468 F +NL LG G++G V L+VAVK+ E+ + +SE + Sbjct: 577 FPRNNLQFGKTLGAGAFGKVVEATAFGLGKEDAVLKVAVKMLKSTAHADEKEALMSELKI 636 Query: 469 LRSV-QHRNLVSIITACS 519 + + QH N+V+++ AC+ Sbjct: 637 MSHLGQHENIVNLLGACT 654
>CSF1R_RAT (Q00495) Macrophage colony-stimulating factor 1 receptor precursor| (CSF-1-R) (EC 2.7.10.1) (Fms proto-oncogene) (c-fms) Length = 978 Score = 37.7 bits (86), Expect = 0.024 Identities = 34/138 (24%), Positives = 66/138 (47%), Gaps = 19/138 (13%) Frame = +1 Query: 163 VLIPLFGFMSLVLLVYFLVLERKMRRTRYESEAPLGEHFPKVSYNDLVEATK-------N 321 V++ MSL++L+ L+L + ++ +Y+ + E + SY ++ T+ Sbjct: 516 VVVACMSVMSLLVLLLLLLLYKYKQKPKYQVRWKIIERYEGNSYT-FIDPTQLPYNEKWE 574 Query: 322 FSESNL-----LGKGSYGTVYRGKLV-----QHKLEVAVKVFNLEMQGAER-SFLSECEA 468 F +NL LG G++G V L+VAVK+ E+ + +SE + Sbjct: 575 FPRNNLQFGKTLGAGAFGKVVEATAFGLGKEDAVLKVAVKMLKSTAHADEKEALMSELKI 634 Query: 469 LRSV-QHRNLVSIITACS 519 + + QH N+V+++ AC+ Sbjct: 635 MSHLGQHENIVNLLGACT 652
>CDK9_BOVIN (Q5EAB2) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 372 Score = 37.7 bits (86), Expect = 0.024 Identities = 25/87 (28%), Positives = 48/87 (55%), Gaps = 2/87 (2%) Frame = +1 Query: 307 EATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVK--VFNLEMQGAERSFLSECEALRSV 480 E TK + + +G+G++G V++ K + +VA+K + E +G + L E + L+ + Sbjct: 15 EVTK-YEKLAKIGQGTFGEVFKAKHRKTGQKVALKKVLMENEKEGFPITALREIKILQLL 73 Query: 481 QHRNLVSIITACSTIDSDGSAFRALIY 561 +H N+V++I C T S + + IY Sbjct: 74 KHENVVNLIEICRTKASPYNRCKGSIY 100
>CSF1R_MOUSE (P09581) Macrophage colony-stimulating factor 1 receptor precursor| (CSF-1-R) (EC 2.7.10.1) (Fms proto-oncogene) (c-fms) Length = 977 Score = 37.7 bits (86), Expect = 0.024 Identities = 34/138 (24%), Positives = 66/138 (47%), Gaps = 19/138 (13%) Frame = +1 Query: 163 VLIPLFGFMSLVLLVYFLVLERKMRRTRYESEAPLGEHFPKVSYNDLVEATK-------N 321 V++ MSL++L+ L+L + ++ +Y+ + E + SY ++ T+ Sbjct: 516 VVVACMSVMSLLVLLLLLLLYKYKQKPKYQVRWKIIERYEGNSYT-FIDPTQLPYNEKWE 574 Query: 322 FSESNL-----LGKGSYGTVYRGKLV-----QHKLEVAVKVFNLEMQGAER-SFLSECEA 468 F +NL LG G++G V L+VAVK+ E+ + +SE + Sbjct: 575 FPRNNLQFGKTLGAGAFGKVVEATAFGLGKEDAVLKVAVKMLKSTAHADEKEALMSELKI 634 Query: 469 LRSV-QHRNLVSIITACS 519 + + QH N+V+++ AC+ Sbjct: 635 MSHLGQHENIVNLLGACT 652
>MLTK_MOUSE (Q9ESL4) Mitogen-activated protein kinase kinase kinase MLT (EC| 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper-and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) ( Length = 802 Score = 37.7 bits (86), Expect = 0.024 Identities = 27/79 (34%), Positives = 40/79 (50%), Gaps = 1/79 (1%) Frame = +1 Query: 265 LGEHFPKVSYNDLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAV-KVFNLEMQGAE 441 LG F ++ ++DL F E+ G GS+G+VYR K + EVAV K+ +E Sbjct: 4 LGASFVQIKFDDL-----QFFEN--CGGGSFGSVYRAKWISQDKEVAVKKLLKIE----- 51 Query: 442 RSFLSECEALRSVQHRNLV 498 E E L + HRN++ Sbjct: 52 ----KEAEILSVLSHRNII 66
>MET_MOUSE (P16056) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1379 Score = 37.7 bits (86), Expect = 0.024 Identities = 26/81 (32%), Positives = 43/81 (53%), Gaps = 4/81 (4%) Frame = +1 Query: 331 SNLLGKGSYGTVYRGKLVQH---KLEVAVKVFNLEMQGAERS-FLSECEALRSVQHRNLV 498 + ++G+G +G VY G L+ + K+ AVK N E S FL+E ++ H N++ Sbjct: 1079 NEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIEEVSQFLTEGIIMKDFSHPNVL 1138 Query: 499 SIITACSTIDSDGSAFRALIY 561 S++ C + S+GS L Y Sbjct: 1139 SLLGIC--LRSEGSPLVVLPY 1157
>PLK4_MOUSE (Q64702) Serine/threonine-protein kinase PLK4 (EC 2.7.11.21)| (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine-protein kinase 18) Length = 925 Score = 37.7 bits (86), Expect = 0.024 Identities = 17/38 (44%), Positives = 25/38 (65%) Frame = +1 Query: 307 EATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFN 420 E ++F NLLGKGS+ VYR + + LEVA+K+ + Sbjct: 7 ERIEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMID 44
>PLK4_HUMAN (O00444) Serine/threonine-protein kinase PLK4 (EC 2.7.11.21)| (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine-protein kinase 18) Length = 970 Score = 37.7 bits (86), Expect = 0.024 Identities = 17/38 (44%), Positives = 25/38 (65%) Frame = +1 Query: 307 EATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFN 420 E ++F NLLGKGS+ VYR + + LEVA+K+ + Sbjct: 7 EKIEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMID 44
>PAK1_CAEEL (Q17850) Serine/threonine-protein kinase pak-1 (EC 2.7.11.1)| (p21-activated kinase 1) (PAK1) (CePAK) Length = 572 Score = 37.7 bits (86), Expect = 0.024 Identities = 18/71 (25%), Positives = 38/71 (53%) Frame = +1 Query: 316 KNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRNL 495 + + + + +G G+ G+VY + + EVA+K NL+ Q + ++E +R +H N+ Sbjct: 293 RKYRKVDKIGSGASGSVYTAIEISTEAEVAIKQMNLKDQPKKELIINEILVMRENKHANI 352 Query: 496 VSIITACSTID 528 V+ + + D Sbjct: 353 VNYLDSYLVCD 363
>NTRK1_RAT (P35739) High affinity nerve growth factor receptor precursor (EC| 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (p140-TrkA) (Slow nerve growth factor receptor) (Trk-A) Length = 799 Score = 37.7 bits (86), Expect = 0.024 Identities = 24/85 (28%), Positives = 42/85 (49%), Gaps = 5/85 (5%) Frame = +1 Query: 340 LGKGSYGTVYRGKLV-----QHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRNLVSI 504 LG+G++G V+ + Q K+ VAVK + A + F E E L +QH+++V Sbjct: 519 LGEGAFGKVFLAECYNLLNDQDKMLVAVKALKETSENARQDFHREAELLTMLQHQHIVRF 578 Query: 505 ITACSTIDSDGSAFRALIYEFMPKG 579 C ++G +++E+M G Sbjct: 579 FGVC----TEGGPL-LMVFEYMRHG 598
>MLTK_HUMAN (Q9NYL2) Mitogen-activated protein kinase kinase kinase MLT (EC| 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper-and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase Length = 800 Score = 37.7 bits (86), Expect = 0.024 Identities = 27/79 (34%), Positives = 40/79 (50%), Gaps = 1/79 (1%) Frame = +1 Query: 265 LGEHFPKVSYNDLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAV-KVFNLEMQGAE 441 LG F ++ ++DL F E+ G GS+G+VYR K + EVAV K+ +E Sbjct: 4 LGASFVQIKFDDL-----QFFEN--CGGGSFGSVYRAKWISQDKEVAVKKLLKIE----- 51 Query: 442 RSFLSECEALRSVQHRNLV 498 E E L + HRN++ Sbjct: 52 ----KEAEILSVLSHRNII 66
>TSSK4_MOUSE (Q9D411) Testis-specific serine/threonine-protein kinase 4 (EC| 2.7.11.1) (TSSK-4) (Testis-specific kinase 4) (TSK-4) Length = 328 Score = 37.7 bits (86), Expect = 0.024 Identities = 20/70 (28%), Positives = 37/70 (52%), Gaps = 3/70 (4%) Frame = +1 Query: 322 FSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAE--RSFL-SECEALRSVQHRN 492 + ++G GSYGTVY + K+ VAVK+ + + + FL E + ++ ++H+ Sbjct: 25 YEVGKIIGHGSYGTVYEAYYTKQKVMVAVKIISKKKASEDYLNKFLPREIQVMKVLRHKY 84 Query: 493 LVSIITACST 522 L++ A T Sbjct: 85 LINFYQAIET 94
>CDC22_MEDSA (Q05006) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| Length = 294 Score = 37.4 bits (85), Expect = 0.031 Identities = 18/65 (27%), Positives = 35/65 (53%), Gaps = 2/65 (3%) Frame = +1 Query: 316 KNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEM--QGAERSFLSECEALRSVQHR 489 + + + +G+G+YG VY+ + +A+K LE +G + + E L+ +QHR Sbjct: 2 EQYEKVEKIGEGTYGVVYKARDRATNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHR 61 Query: 490 NLVSI 504 N+V + Sbjct: 62 NIVRL 66
>MATK_RAT (P41243) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase BATK) Length = 467 Score = 37.4 bits (85), Expect = 0.031 Identities = 20/56 (35%), Positives = 34/56 (60%) Frame = +1 Query: 340 LGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRNLVSII 507 +G+G +G V +G+ + K VAVK N++ ++FL E + +QHRNLV ++ Sbjct: 200 IGEGEFGAVLQGEYLGQK--VAVK--NIKCDVTAQAFLDETAVMTKLQHRNLVRLL 251
>AAPK1_CAEEL (P45894) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMP-activated kinase 1) Length = 589 Score = 37.4 bits (85), Expect = 0.031 Identities = 20/71 (28%), Positives = 36/71 (50%), Gaps = 3/71 (4%) Frame = +1 Query: 319 NFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFN---LEMQGAERSFLSECEALRSVQHR 489 NF +GKG++G V RG +Q +VA+K+ N ++ G +E + L+ + H Sbjct: 23 NFVIKETIGKGAFGAVKRGTHIQTGYDVAIKILNRGRMKGLGTVNKTRNEIDNLQKLTHP 82 Query: 490 NLVSIITACST 522 ++ + ST Sbjct: 83 HITRLFRVIST 93
>RON_HUMAN (Q04912) Macrophage-stimulating protein receptor precursor (EC| 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain] Length = 1400 Score = 37.4 bits (85), Expect = 0.031 Identities = 21/62 (33%), Positives = 39/62 (62%), Gaps = 5/62 (8%) Frame = +1 Query: 337 LLGKGSYGTVYRGKLV---QHKLEVAVKVFN--LEMQGAERSFLSECEALRSVQHRNLVS 501 ++GKG +G VY G+ + Q++++ A+K + EMQ E +FL E +R + H N+++ Sbjct: 1087 VIGKGHFGVVYHGEYIDQAQNRIQCAIKSLSRITEMQQVE-AFLREGLLMRGLNHPNVLA 1145 Query: 502 II 507 +I Sbjct: 1146 LI 1147
>NTRK3_HUMAN (Q16288) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C) Length = 839 Score = 37.4 bits (85), Expect = 0.031 Identities = 24/85 (28%), Positives = 40/85 (47%), Gaps = 5/85 (5%) Frame = +1 Query: 340 LGKGSYGTVYRGKL-----VQHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRNLVSI 504 LG+G++G V+ + + K+ VAVK A + F E E L ++QH ++V Sbjct: 544 LGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKF 603 Query: 505 ITACSTIDSDGSAFRALIYEFMPKG 579 C DG +++E+M G Sbjct: 604 YGVC----GDGDPL-IMVFEYMKHG 623
>MDS1_YEAST (P38615) Serine/threonine-protein kinase MDS1/RIM11 (EC 2.7.11.1)| Length = 370 Score = 37.4 bits (85), Expect = 0.031 Identities = 25/99 (25%), Positives = 48/99 (48%) Frame = +1 Query: 280 PKVSYNDLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSE 459 P + ND V+ + F + ++G GS+G V+ + + +VA+K + + R E Sbjct: 27 PTIDPNDPVQIS--FPTTEVVGHGSFGVVFATVIQETNEKVAIKKVLQDKRFKNR----E 80 Query: 460 CEALRSVQHRNLVSIITACSTIDSDGSAFRALIYEFMPK 576 E ++ + H N++ + DS + LI E+MP+ Sbjct: 81 LEIMKMLSHINIIDLKYFFYERDSQDEIYLNLILEYMPQ 119
>NTRK2_CHICK (Q91987) BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (Trk-B) Length = 818 Score = 37.4 bits (85), Expect = 0.031 Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 5/85 (5%) Frame = +1 Query: 340 LGKGSYGTVYRGKLV-----QHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRNLVSI 504 LG+G++G V+ + Q K+ VAVK A + F E E L ++QH ++V Sbjct: 540 LGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNARKDFHREAELLTNLQHEHIVKF 599 Query: 505 ITACSTIDSDGSAFRALIYEFMPKG 579 C D +++E+M G Sbjct: 600 YGVCVEGDP-----LIMVFEYMKHG 619
>M3K5_HUMAN (Q99683) Mitogen-activated protein kinase kinase kinase 5 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5) (Apoptosis signal-regulating kinase 1) (ASK-1) Length = 1374 Score = 37.4 bits (85), Expect = 0.031 Identities = 24/98 (24%), Positives = 48/98 (48%), Gaps = 3/98 (3%) Frame = +1 Query: 295 NDLVEATKNFSESN---LLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSECE 465 +DL+E + E+ +LGKG+YG VY G+ + +++ +A+K + E Sbjct: 668 SDLLEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIA 727 Query: 466 ALRSVQHRNLVSIITACSTIDSDGSAFRALIYEFMPKG 579 + ++H+N+V + + S + F + E +P G Sbjct: 728 LHKHLKHKNIVQYLGSFSE-----NGFIKIFMEQVPGG 760
>NTRK2_HUMAN (Q16620) BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB) (Trk-B) Length = 822 Score = 37.4 bits (85), Expect = 0.031 Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 5/85 (5%) Frame = +1 Query: 340 LGKGSYGTVYRGKLV-----QHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRNLVSI 504 LG+G++G V+ + Q K+ VAVK A + F E E L ++QH ++V Sbjct: 544 LGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNARKDFHREAELLTNLQHEHIVKF 603 Query: 505 ITACSTIDSDGSAFRALIYEFMPKG 579 C D +++E+M G Sbjct: 604 YGVCVEGDP-----LIMVFEYMKHG 623
>CDC7_SCHPO (P41892) Cell division control protein 7 (EC 2.7.11.1)| Length = 1062 Score = 37.4 bits (85), Expect = 0.031 Identities = 24/66 (36%), Positives = 39/66 (59%), Gaps = 2/66 (3%) Frame = +1 Query: 340 LGKGSYGTVYRGKLVQHKLEVAVKVFNL-EMQGAERSFLS-ECEALRSVQHRNLVSIITA 513 LGKG++G VYRG +++ VAVK L +M ++ S + E + L+++ H N+V + Sbjct: 15 LGKGAFGAVYRGLNIKNGETVAVKKVKLSKMLKSDLSVIKMEIDLLKNLDHPNIVKYRGS 74 Query: 514 CSTIDS 531 T DS Sbjct: 75 YQTNDS 80
>NTRK1_HUMAN (P04629) High affinity nerve growth factor receptor precursor (EC| 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1 transforming tyrosine kinase protein) (p140-TrkA) (Trk-A) Length = 796 Score = 37.4 bits (85), Expect = 0.031 Identities = 24/85 (28%), Positives = 42/85 (49%), Gaps = 5/85 (5%) Frame = +1 Query: 340 LGKGSYGTVYRGKL-----VQHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRNLVSI 504 LG+G++G V+ + Q K+ VAVK + A + F E E L +QH+++V Sbjct: 516 LGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRF 575 Query: 505 ITACSTIDSDGSAFRALIYEFMPKG 579 C ++G +++E+M G Sbjct: 576 FGVC----TEGRPL-LMVFEYMRHG 595
>PHO85_KLULA (Q92241) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 304 Score = 37.4 bits (85), Expect = 0.031 Identities = 23/88 (26%), Positives = 42/88 (47%), Gaps = 1/88 (1%) Frame = +1 Query: 310 ATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEM-QGAERSFLSECEALRSVQH 486 A F + +G G+Y TVY+G + VA+K L+ +G + + E ++ ++H Sbjct: 3 APSQFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKH 62 Query: 487 RNLVSIITACSTIDSDGSAFRALIYEFM 570 N+V + T + L++EFM Sbjct: 63 DNIVRLFDVIHTENK-----LTLVFEFM 85
>NTRK2_RAT (Q63604) BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B) Length = 821 Score = 37.4 bits (85), Expect = 0.031 Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 5/85 (5%) Frame = +1 Query: 340 LGKGSYGTVYRGKLV-----QHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRNLVSI 504 LG+G++G V+ + Q K+ VAVK A + F E E L ++QH ++V Sbjct: 543 LGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNARKDFHREAELLTNLQHEHIVKF 602 Query: 505 ITACSTIDSDGSAFRALIYEFMPKG 579 C D +++E+M G Sbjct: 603 YGVCVEGDP-----LIMVFEYMKHG 622
>NTRK2_MOUSE (P15209) BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B) Length = 821 Score = 37.4 bits (85), Expect = 0.031 Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 5/85 (5%) Frame = +1 Query: 340 LGKGSYGTVYRGKLV-----QHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRNLVSI 504 LG+G++G V+ + Q K+ VAVK A + F E E L ++QH ++V Sbjct: 543 LGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNARKDFHREAELLTNLQHEHIVKF 602 Query: 505 ITACSTIDSDGSAFRALIYEFMPKG 579 C D +++E+M G Sbjct: 603 YGVCVEGDP-----LIMVFEYMKHG 622
>FAK2_MOUSE (Q9QVP9) Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal| adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinas Length = 1009 Score = 37.4 bits (85), Expect = 0.031 Identities = 20/63 (31%), Positives = 35/63 (55%), Gaps = 4/63 (6%) Frame = +1 Query: 331 SNLLGKGSYGTVYRGKLVQH---KLEVAVKVFNLE-MQGAERSFLSECEALRSVQHRNLV 498 + +LG+G +G VY G H K+ VAVK + Q + F+SE ++++ H ++V Sbjct: 428 NRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTQDNKEKFMSEAVIMKNLDHPHIV 487 Query: 499 SII 507 +I Sbjct: 488 KLI 490
>CDK7_MOUSE (Q03147) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (Protein-tyrosine kinase MPK-7) (CR4 protein kinas Length = 346 Score = 37.4 bits (85), Expect = 0.031 Identities = 20/77 (25%), Positives = 37/77 (48%), Gaps = 5/77 (6%) Frame = +1 Query: 298 DLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNL-----EMQGAERSFLSEC 462 D+ K + + + LG+G + TVY+ + VA+K L G R+ L E Sbjct: 4 DVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREI 63 Query: 463 EALRSVQHRNLVSIITA 513 + L+ + H N++ ++ A Sbjct: 64 KLLQELSHPNIIGLLDA 80
>CDK7_HUMAN (P50613) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (STK1) (CAK1) Length = 346 Score = 37.4 bits (85), Expect = 0.031 Identities = 20/77 (25%), Positives = 37/77 (48%), Gaps = 5/77 (6%) Frame = +1 Query: 298 DLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNL-----EMQGAERSFLSEC 462 D+ K + + + LG+G + TVY+ + VA+K L G R+ L E Sbjct: 4 DVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREI 63 Query: 463 EALRSVQHRNLVSIITA 513 + L+ + H N++ ++ A Sbjct: 64 KLLQELSHPNIIGLLDA 80
>BUR1_CANGA (Q6FQ83) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 667 Score = 37.4 bits (85), Expect = 0.031 Identities = 19/65 (29%), Positives = 37/65 (56%), Gaps = 2/65 (3%) Frame = +1 Query: 319 NFSESNLLGKGSYGTVYRGKLVQHKLEVAVK--VFNLEMQGAERSFLSECEALRSVQHRN 492 N+ E LG+G++G VY+G +Q + +VA+K + N E + E L+ + H+N Sbjct: 59 NYKEEEKLGQGTFGEVYKGLHLQTQRKVAMKRIIVNQENDLFPITAQREITILKRLNHKN 118 Query: 493 LVSII 507 ++ ++ Sbjct: 119 IIKLL 123
>PR2_DROME (Q9I7F7) Tyrosine-protein kinase PR2 (EC 2.7.10.2)| Length = 1337 Score = 37.4 bits (85), Expect = 0.031 Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 3/86 (3%) Frame = +1 Query: 283 KVSYNDLVEATKNFSESNLLGKGSYGTVYRGKLVQ--HKLEVAVKVFNLE-MQGAERSFL 453 KV N + + S + LG G +G V +G +++VA+K E MQ FL Sbjct: 120 KVPNNKHIIPADSISVNKQLGTGEFGIVQQGVWSNGNERIQVAIKCLCRERMQSNPMEFL 179 Query: 454 SECEALRSVQHRNLVSIITACSTIDS 531 E + S++H N+V + DS Sbjct: 180 KEAAIMHSIEHENIVRLYGVVLATDS 205
>NTRK3_SAIBB (Q5IS82) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) Length = 825 Score = 37.4 bits (85), Expect = 0.031 Identities = 24/85 (28%), Positives = 40/85 (47%), Gaps = 5/85 (5%) Frame = +1 Query: 340 LGKGSYGTVYRGKL-----VQHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRNLVSI 504 LG+G++G V+ + + K+ VAVK A + F E E L ++QH ++V Sbjct: 544 LGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKF 603 Query: 505 ITACSTIDSDGSAFRALIYEFMPKG 579 C DG +++E+M G Sbjct: 604 YGVC----GDGDPL-IMVFEYMKHG 623
>NTRK3_RAT (Q03351) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C) Length = 864 Score = 37.4 bits (85), Expect = 0.031 Identities = 24/85 (28%), Positives = 40/85 (47%), Gaps = 5/85 (5%) Frame = +1 Query: 340 LGKGSYGTVYRGKL-----VQHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRNLVSI 504 LG+G++G V+ + + K+ VAVK A + F E E L ++QH ++V Sbjct: 544 LGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKF 603 Query: 505 ITACSTIDSDGSAFRALIYEFMPKG 579 C DG +++E+M G Sbjct: 604 YGVC----GDGDPL-IMVFEYMKHG 623
>NTRK3_PANTR (Q5IS37) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) Length = 825 Score = 37.4 bits (85), Expect = 0.031 Identities = 24/85 (28%), Positives = 40/85 (47%), Gaps = 5/85 (5%) Frame = +1 Query: 340 LGKGSYGTVYRGKL-----VQHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRNLVSI 504 LG+G++G V+ + + K+ VAVK A + F E E L ++QH ++V Sbjct: 544 LGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKF 603 Query: 505 ITACSTIDSDGSAFRALIYEFMPKG 579 C DG +++E+M G Sbjct: 604 YGVC----GDGDPL-IMVFEYMKHG 623
>NTRK3_MACFA (Q5IFJ9) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) Length = 825 Score = 37.4 bits (85), Expect = 0.031 Identities = 24/85 (28%), Positives = 40/85 (47%), Gaps = 5/85 (5%) Frame = +1 Query: 340 LGKGSYGTVYRGKL-----VQHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRNLVSI 504 LG+G++G V+ + + K+ VAVK A + F E E L ++QH ++V Sbjct: 544 LGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKF 603 Query: 505 ITACSTIDSDGSAFRALIYEFMPKG 579 C DG +++E+M G Sbjct: 604 YGVC----GDGDPL-IMVFEYMKHG 623
>MATK_MOUSE (P41242) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK) Length = 505 Score = 37.4 bits (85), Expect = 0.031 Identities = 20/56 (35%), Positives = 34/56 (60%) Frame = +1 Query: 340 LGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRNLVSII 507 +G+G +G V +G+ + K VAVK N++ ++FL E + +QHRNLV ++ Sbjct: 239 IGEGEFGAVLQGEYLGQK--VAVK--NIKCDVTAQAFLDETAVMTKLQHRNLVRLL 290
>ERBB2_RAT (P06494) Receptor tyrosine-protein kinase erbB-2 precursor (EC| 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Epidermal growth factor receptor-related protein) Length = 1257 Score = 37.4 bits (85), Expect = 0.031 Identities = 44/179 (24%), Positives = 79/179 (44%), Gaps = 17/179 (9%) Frame = +1 Query: 94 ELHMPACPVASHRGTKIRYYLIRVLIPLFGFMSLVLLVYFLVLERK-------MRRTRYE 252 +L CP A R + + + +I ++ + F+ LV++V L+ R+ MRR E Sbjct: 638 DLDERGCP-AEQRASPVTF-IIATVVGVLLFLILVVVVGILIKRRRQKIRKYTMRRLLQE 695 Query: 253 SE-----APLGEHFPKVSYNDLVEATKNFSESNLLGKGSYGTVYRGKLVQH----KLEVA 405 +E P G P + +++ T+ + +LG G++GTVY+G + K+ VA Sbjct: 696 TELVEPLTPSGA-MPNQAQMRILKETE-LRKVKVLGSGAFGTVYKGIWIPDGENVKIPVA 753 Query: 406 VKVFNLEMQ-GAERSFLSECEALRSVQHRNLVSIITACSTIDSDGSAFRALIYEFMPKG 579 +KV A + L E + V + ++ C T + L+ + MP G Sbjct: 754 IKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLT------STVQLVTQLMPYG 806
>CDK9_XENTR (Q6GLD8) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 376 Score = 37.4 bits (85), Expect = 0.031 Identities = 20/63 (31%), Positives = 38/63 (60%), Gaps = 2/63 (3%) Frame = +1 Query: 340 LGKGSYGTVYRGKLVQHKLEVAVK--VFNLEMQGAERSFLSECEALRSVQHRNLVSIITA 513 +G+G++G V++ K Q +VA+K + E +G + L E + L+ ++H N+V++I Sbjct: 25 IGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEI 84 Query: 514 CST 522 C T Sbjct: 85 CRT 87
>CDK9A_XENLA (Q4V862) Cell division protein kinase 9-A (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9-A) Length = 376 Score = 37.4 bits (85), Expect = 0.031 Identities = 20/63 (31%), Positives = 38/63 (60%), Gaps = 2/63 (3%) Frame = +1 Query: 340 LGKGSYGTVYRGKLVQHKLEVAVK--VFNLEMQGAERSFLSECEALRSVQHRNLVSIITA 513 +G+G++G V++ K Q +VA+K + E +G + L E + L+ ++H N+V++I Sbjct: 25 IGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEI 84 Query: 514 CST 522 C T Sbjct: 85 CRT 87
>ROR1_DROME (Q24488) Tyrosine-protein kinase transmembrane receptor Ror| precursor (EC 2.7.10.1) (dRor) Length = 685 Score = 37.4 bits (85), Expect = 0.031 Identities = 19/60 (31%), Positives = 38/60 (63%), Gaps = 4/60 (6%) Frame = +1 Query: 340 LGKGSYGTVYRGKLVQ-HKLEVAVKVFNLEMQGA---ERSFLSECEALRSVQHRNLVSII 507 LG+G++G VY+G+L+Q +K + V + L+ + ++ F E E + ++H+N+V I+ Sbjct: 416 LGEGAFGKVYKGQLLQPNKTTITVAIKALKENASVKTQQDFKREIELISDLKHQNIVCIL 475
>LRRK2_MOUSE (Q5S006) Leucine-rich repeat serine/threonine-protein kinase 2 (EC| 2.7.11.1) Length = 2527 Score = 37.0 bits (84), Expect = 0.041 Identities = 29/81 (35%), Positives = 39/81 (48%) Frame = +1 Query: 337 LLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRNLVSIITAC 516 LLG GS+G+VYR EVAVK+FN + R E L + H +L+S++ A Sbjct: 1884 LLGDGSFGSVYRA--AYEGEEVAVKIFN--KHTSLRLLRQELVVLCHLHHPSLISLLAA- 1938 Query: 517 STIDSDGSAFRALIYEFMPKG 579 G R L+ E KG Sbjct: 1939 ------GIRPRMLVMELASKG 1953
>LRRK2_HUMAN (Q5S007) Leucine-rich repeat serine/threonine-protein kinase 2 (EC| 2.7.11.1) (Dardarin) Length = 2527 Score = 37.0 bits (84), Expect = 0.041 Identities = 29/81 (35%), Positives = 39/81 (48%) Frame = +1 Query: 337 LLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRNLVSIITAC 516 LLG GS+G+VYR EVAVK+FN + R E L + H +L+S++ A Sbjct: 1884 LLGDGSFGSVYRA--AYEGEEVAVKIFN--KHTSLRLLRQELVVLCHLHHPSLISLLAA- 1938 Query: 517 STIDSDGSAFRALIYEFMPKG 579 G R L+ E KG Sbjct: 1939 ------GIRPRMLVMELASKG 1953
>ARAF_HUMAN (P10398) A-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (A-raf-1) (Proto-oncogene Pks) Length = 606 Score = 37.0 bits (84), Expect = 0.041 Identities = 21/55 (38%), Positives = 34/55 (61%), Gaps = 2/55 (3%) Frame = +1 Query: 340 LGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAE--RSFLSECEALRSVQHRNLV 498 +G GS+GTV+RG+ +VAVKV + AE ++F +E + LR +H N++ Sbjct: 316 IGTGSFGTVFRGR---WHGDVAVKVLKVSQPTAEQAQAFKNEMQVLRKTRHVNIL 367
>TRK1_LYMST (O76997) Putative neurotrophin receptor LTRK 1 precursor (EC| 2.7.10.1) Length = 794 Score = 37.0 bits (84), Expect = 0.041 Identities = 25/87 (28%), Positives = 42/87 (48%), Gaps = 6/87 (6%) Frame = +1 Query: 337 LLGKGSYGTVYRGK---LVQHKLEVAVKVFNLE---MQGAERSFLSECEALRSVQHRNLV 498 ++G+G++G V+ G L+Q V V L+ +R F E E L +++H N+V Sbjct: 509 VIGEGAFGRVFLGTCAHLIQKNEFAIVAVKTLKGSCSDSLKRDFEREAEMLATIEHANIV 568 Query: 499 SIITACSTIDSDGSAFRALIYEFMPKG 579 + C+ D +I+EFM G Sbjct: 569 TFYGVCTESDQ-----WMMIFEFMENG 590
>PAK2_RABIT (Q29502) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) (Gamma-PAK) (p21-activated protein kinase I) (PAKI) Length = 524 Score = 37.0 bits (84), Expect = 0.041 Identities = 22/95 (23%), Positives = 49/95 (51%) Frame = +1 Query: 223 ERKMRRTRYESEAPLGEHFPKVSYNDLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEV 402 +++ ++T+ E + + VS D K ++ +G+G+ GTV+ V EV Sbjct: 219 DKQKKKTKMTDEEIMEKLRTIVSIGD---PKKKYTRYEKIGQGASGTVFTATDVALGQEV 275 Query: 403 AVKVFNLEMQGAERSFLSECEALRSVQHRNLVSII 507 A+K NL+ Q + ++E ++ +++ N+V+ + Sbjct: 276 AIKQINLQKQPKKELIINEILVMKELKNPNIVNFL 310
>TGFR1_RAT (P80204) TGF-beta receptor type-1 precursor (EC 2.7.11.30)| (TGF-beta receptor type I) (TGFR-1) (TGF-beta type I receptor) (Serine/threonine-protein kinase receptor R4) (SKR4) Length = 501 Score = 37.0 bits (84), Expect = 0.041 Identities = 24/60 (40%), Positives = 35/60 (58%), Gaps = 2/60 (3%) Frame = +1 Query: 340 LGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSECEALRSV--QHRNLVSIITA 513 +GKG +G V+RGK EVAVK+F+ ERS+ E E ++V +H N++ I A Sbjct: 209 IGKGRFGEVWRGK--WRGEEVAVKIFS---SREERSWFREAEIYQTVMLRHENILGFIAA 263
>TGFR1_MOUSE (Q64729) TGF-beta receptor type-1 precursor (EC 2.7.11.30)| (TGF-beta receptor type I) (TGFR-1) (TGF-beta type I receptor) (ESK2) Length = 503 Score = 37.0 bits (84), Expect = 0.041 Identities = 24/60 (40%), Positives = 35/60 (58%), Gaps = 2/60 (3%) Frame = +1 Query: 340 LGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSECEALRSV--QHRNLVSIITA 513 +GKG +G V+RGK EVAVK+F+ ERS+ E E ++V +H N++ I A Sbjct: 211 IGKGRFGEVWRGK--WRGEEVAVKIFS---SREERSWFREAEIYQTVMLRHENILGFIAA 265
>TGFR1_HUMAN (P36897) TGF-beta receptor type-1 precursor (EC 2.7.11.30)| (TGF-beta receptor type I) (TGFR-1) (TGF-beta type I receptor) (Serine/threonine-protein kinase receptor R4) (SKR4) (Activin receptor-like kinase 5) (ALK-5) Length = 503 Score = 37.0 bits (84), Expect = 0.041 Identities = 24/60 (40%), Positives = 35/60 (58%), Gaps = 2/60 (3%) Frame = +1 Query: 340 LGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSECEALRSV--QHRNLVSIITA 513 +GKG +G V+RGK EVAVK+F+ ERS+ E E ++V +H N++ I A Sbjct: 211 IGKGRFGEVWRGK--WRGEEVAVKIFS---SREERSWFREAEIYQTVMLRHENILGFIAA 265
>NTRK3_CHICK (Q91044) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (Trk-C) Length = 827 Score = 37.0 bits (84), Expect = 0.041 Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 5/85 (5%) Frame = +1 Query: 340 LGKGSYGTVYRGKL-----VQHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRNLVSI 504 LG+G++G V+ + K+ VAVK A + F E E L ++QH ++V Sbjct: 546 LGEGAFGKVFLAECYNLSPTNDKMLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKF 605 Query: 505 ITACSTIDSDGSAFRALIYEFMPKG 579 C DG +++E+M G Sbjct: 606 YGVC----GDGDPL-IMVFEYMKHG 625
>PCTK3_RAT (O35832) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 451 Score = 37.0 bits (84), Expect = 0.041 Identities = 25/78 (32%), Positives = 44/78 (56%), Gaps = 1/78 (1%) Frame = +1 Query: 340 LGKGSYGTVYRGKLVQHKLEVAVKVFNLE-MQGAERSFLSECEALRSVQHRNLVSIITAC 516 LG+G+Y TV++G+ + VA+K LE +GA + + E L+ ++H N I+T Sbjct: 127 LGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHAN---IVTLH 183 Query: 517 STIDSDGSAFRALIYEFM 570 I +D S L++E++ Sbjct: 184 DLIHTDRSL--TLVFEYL 199
>PCTK3_MOUSE (Q04899) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 451 Score = 37.0 bits (84), Expect = 0.041 Identities = 25/78 (32%), Positives = 44/78 (56%), Gaps = 1/78 (1%) Frame = +1 Query: 340 LGKGSYGTVYRGKLVQHKLEVAVKVFNLE-MQGAERSFLSECEALRSVQHRNLVSIITAC 516 LG+G+Y TV++G+ + VA+K LE +GA + + E L+ ++H N I+T Sbjct: 127 LGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHAN---IVTLH 183 Query: 517 STIDSDGSAFRALIYEFM 570 I +D S L++E++ Sbjct: 184 DLIHTDRSL--TLVFEYL 199
>GSK31_SCHPO (Q9URT9) Protein kinase gsk31 (EC 2.7.11.1)| Length = 381 Score = 37.0 bits (84), Expect = 0.041 Identities = 25/89 (28%), Positives = 44/89 (49%), Gaps = 1/89 (1%) Frame = +1 Query: 313 TKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRN 492 T ++ +LG GS+G V + KLV +AVK + + R E + +R++ H N Sbjct: 22 TISYEPCRVLGSGSFGVVIQAKLVGTPGFIAVKRVLQDKRYKNR----ELQIMRAISHPN 77 Query: 493 LVSIITACSTID-SDGSAFRALIYEFMPK 576 ++ +I T + S L+ E+MP+ Sbjct: 78 IIKLIAFFHTHNPSKDETHLCLLLEYMPE 106
>CDC21_MEDSA (P24923) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (Fragment) Length = 291 Score = 37.0 bits (84), Expect = 0.041 Identities = 22/79 (27%), Positives = 42/79 (53%), Gaps = 2/79 (2%) Frame = +1 Query: 340 LGKGSYGTVYRGKLVQHKLEVAVKVFNLEM--QGAERSFLSECEALRSVQHRNLVSIITA 513 +G+G+YG VY+ + +A+K LE +G + + E L+ +QHRN+V + Sbjct: 7 IGEGTYGVVYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHRNIVRL--- 63 Query: 514 CSTIDSDGSAFRALIYEFM 570 + SD + L++E++ Sbjct: 64 QDVVHSDKRLY--LVFEYL 80
>PHO85_CANGA (Q6FKD4) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 302 Score = 37.0 bits (84), Expect = 0.041 Identities = 22/88 (25%), Positives = 43/88 (48%), Gaps = 1/88 (1%) Frame = +1 Query: 310 ATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEM-QGAERSFLSECEALRSVQH 486 ++ F + LG G+Y TVY+G + VA+K L+ +G + + E ++ ++H Sbjct: 2 SSSQFKQLEKLGNGTYATVYKGLNKSTGVYVALKEVKLDSEEGTPSTAIREISLMKELKH 61 Query: 487 RNLVSIITACSTIDSDGSAFRALIYEFM 570 N+V + T + L++E+M Sbjct: 62 DNIVRLYDVIHTENK-----LTLVFEYM 84
>CDPK3_PLAYO (Q7RAV5) Calcium-dependent protein kinase 3 (EC 2.7.11.1)| Length = 538 Score = 37.0 bits (84), Expect = 0.041 Identities = 22/74 (29%), Positives = 40/74 (54%) Frame = +1 Query: 286 VSYNDLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSECE 465 +S+ +E N SE L GKG+YG VY+ K++ AVKV + + F E + Sbjct: 101 LSFTGNLEDFYNLSEEPL-GKGTYGCVYKATDKLLKIQRAVKVVSKKKLKNIPRFRQEID 159 Query: 466 ALRSVQHRNLVSII 507 ++++ H N++ ++ Sbjct: 160 IMKNLDHPNVIKLL 173
>CDK5_DROME (P48609) Cell division protein kinase 5 homolog (EC 2.7.11.22)| Length = 294 Score = 37.0 bits (84), Expect = 0.041 Identities = 20/66 (30%), Positives = 38/66 (57%), Gaps = 2/66 (3%) Frame = +1 Query: 316 KNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEM--QGAERSFLSECEALRSVQHR 489 + + + +G+G+YGTV++G+ VA+K L+ +G S L E L+ ++H+ Sbjct: 2 QKYDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELKHK 61 Query: 490 NLVSII 507 N+V +I Sbjct: 62 NIVRLI 67
>CDC2_VIGAC (Q41639) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 37.0 bits (84), Expect = 0.041 Identities = 18/65 (27%), Positives = 35/65 (53%), Gaps = 2/65 (3%) Frame = +1 Query: 316 KNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEM--QGAERSFLSECEALRSVQHR 489 + + + +G+G+YG VY+ + +A+K LE +G + + E L+ +QHR Sbjct: 2 EQYEKVEKIGEGTYGVVYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHR 61 Query: 490 NLVSI 504 N+V + Sbjct: 62 NIVRL 66
>MET_RAT (P97523) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 37.0 bits (84), Expect = 0.041 Identities = 26/81 (32%), Positives = 42/81 (51%), Gaps = 4/81 (4%) Frame = +1 Query: 331 SNLLGKGSYGTVYRGKLVQ---HKLEVAVKVFNLEMQGAERS-FLSECEALRSVQHRNLV 498 + ++G+G +G VY G L+ K+ AVK N E S FL+E ++ H N++ Sbjct: 1082 NEVIGRGHFGCVYHGTLLDSDGKKIHCAVKSLNRITDIEEVSQFLTEGIIMKDFSHPNVL 1141 Query: 499 SIITACSTIDSDGSAFRALIY 561 S++ C + S+GS L Y Sbjct: 1142 SLLGIC--LRSEGSPLVVLPY 1160
>KPK2_PLAFK (Q02595) Probable serine/threonine-protein kinase 2 (EC 2.7.11.1)| Length = 510 Score = 36.6 bits (83), Expect = 0.053 Identities = 22/74 (29%), Positives = 39/74 (52%) Frame = +1 Query: 340 LGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRNLVSIITACS 519 +GKGS+ T Y G + + V VK + + + E + +E E LR V H+ ++ +I+A Sbjct: 117 IGKGSFSTAYIGTNILYGNRVVVKEVD-KSKVKESNVYTEIEVLRKVMHKYIIKLISA-- 173 Query: 520 TIDSDGSAFRALIY 561 + +G + L Y Sbjct: 174 -YEQEGFVYLVLEY 186
>ARAF_PIG (O19004) A-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (A-Raf-1) Length = 606 Score = 36.6 bits (83), Expect = 0.053 Identities = 21/55 (38%), Positives = 34/55 (61%), Gaps = 2/55 (3%) Frame = +1 Query: 340 LGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAE--RSFLSECEALRSVQHRNLV 498 +G GS+GTV+RG+ +VAVKV + AE ++F +E + LR +H N++ Sbjct: 316 IGTGSFGTVFRGR---WHGDVAVKVLKVAQPTAEQAQAFKNEMQVLRKTRHVNIL 367
>ARAF_RAT (P14056) A-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) Length = 604 Score = 36.6 bits (83), Expect = 0.053 Identities = 21/55 (38%), Positives = 34/55 (61%), Gaps = 2/55 (3%) Frame = +1 Query: 340 LGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAE--RSFLSECEALRSVQHRNLV 498 +G GS+GTV+RG+ +VAVKV + AE ++F +E + LR +H N++ Sbjct: 314 IGTGSFGTVFRGR---WHGDVAVKVLKVAQPTAEQAQAFKNEMQVLRKTRHVNIL 365
>ARAF_MOUSE (P04627) A-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) Length = 604 Score = 36.6 bits (83), Expect = 0.053 Identities = 21/55 (38%), Positives = 34/55 (61%), Gaps = 2/55 (3%) Frame = +1 Query: 340 LGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAE--RSFLSECEALRSVQHRNLV 498 +G GS+GTV+RG+ +VAVKV + AE ++F +E + LR +H N++ Sbjct: 314 IGTGSFGTVFRGR---WHGDVAVKVLKVAQPTAEQAQAFKNEMQVLRKTRHVNIL 365
>KCC2_SCHPO (O42844) Calcium/calmodulin-dependent protein kinase type II (EC| 2.7.11.17) (CAM kinase II) Length = 504 Score = 36.6 bits (83), Expect = 0.053 Identities = 22/65 (33%), Positives = 33/65 (50%), Gaps = 2/65 (3%) Frame = +1 Query: 340 LGKGSYGTVYRGKLVQHKLEVAVKVF-NLEMQGAER-SFLSECEALRSVQHRNLVSIITA 513 LG G++ VY+ + K VAVKV EM +R E +R V+H+N+V++ Sbjct: 71 LGDGAFSQVYKAYSIDRKEHVAVKVIRKYEMNKKQRQGVFKEVNIMRRVKHKNVVNLFDF 130 Query: 514 CSTID 528 T D Sbjct: 131 VETED 135
>CDC2_PONPY (Q5RCH1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 36.6 bits (83), Expect = 0.053 Identities = 18/65 (27%), Positives = 37/65 (56%), Gaps = 2/65 (3%) Frame = +1 Query: 316 KNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEM--QGAERSFLSECEALRSVQHR 489 +++++ +G+G+YG VY+G+ V +K LE +G + + E L+ ++H Sbjct: 2 EDYTKIEKIGEGTYGVVYKGRHKTTGQVVTMKKIRLESEEEGVPSTAIREISLLKELRHP 61 Query: 490 NLVSI 504 N+VS+ Sbjct: 62 NIVSL 66
>CDC2_DROME (P23572) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 297 Score = 36.6 bits (83), Expect = 0.053 Identities = 19/65 (29%), Positives = 36/65 (55%), Gaps = 2/65 (3%) Frame = +1 Query: 316 KNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEM--QGAERSFLSECEALRSVQHR 489 ++F + +G+G+YG VY+G+ VA+K LE +G + + E L+ ++H Sbjct: 2 EDFEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKHE 61 Query: 490 NLVSI 504 N+V + Sbjct: 62 NIVCL 66
>EPHB1_RAT (P09759) Ephrin type-B receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-2) (ELK) Length = 984 Score = 36.6 bits (83), Expect = 0.053 Identities = 24/85 (28%), Positives = 42/85 (49%), Gaps = 13/85 (15%) Frame = +1 Query: 289 SYNDLVEATKNFSES---------NLLGKGSYGTVYRGKL-VQHKLEVAVKVFNLEMQGA 438 +Y D EA + F++ ++G G +G VY+G+L + K E+ V + L+ + Sbjct: 599 TYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYS 658 Query: 439 E---RSFLSECEALRSVQHRNLVSI 504 E R FLSE + H N++ + Sbjct: 659 EKQRRDFLSEASIMGQFDHPNIIRL 683
>EPHB1_HUMAN (P54762) Ephrin type-B receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK) Length = 984 Score = 36.6 bits (83), Expect = 0.053 Identities = 24/85 (28%), Positives = 42/85 (49%), Gaps = 13/85 (15%) Frame = +1 Query: 289 SYNDLVEATKNFSES---------NLLGKGSYGTVYRGKL-VQHKLEVAVKVFNLEMQGA 438 +Y D EA + F++ ++G G +G VY+G+L + K E+ V + L+ + Sbjct: 599 TYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYS 658 Query: 439 E---RSFLSECEALRSVQHRNLVSI 504 E R FLSE + H N++ + Sbjct: 659 EKQRRDFLSEASIMGQFDHPNIIRL 683
>EPHB1_CHICK (Q07494) Ephrin type-B receptor 1 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor EPH-2) (Tyrosine kinase CEK6 receptor) (Fragment) Length = 984 Score = 36.6 bits (83), Expect = 0.053 Identities = 24/85 (28%), Positives = 42/85 (49%), Gaps = 13/85 (15%) Frame = +1 Query: 289 SYNDLVEATKNFSES---------NLLGKGSYGTVYRGKL-VQHKLEVAVKVFNLEMQGA 438 +Y D EA + F++ ++G G +G VY+G+L + K E+ V + L+ + Sbjct: 599 TYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYS 658 Query: 439 E---RSFLSECEALRSVQHRNLVSI 504 E R FLSE + H N++ + Sbjct: 659 EKQRRDFLSEASIMGQFDHPNIIRL 683
>AURKB_MOUSE (O70126) Serine/threonine-protein kinase 12 (EC 2.7.11.1)| (Aurora-related kinase 2) (Serine/threonine-protein kinase 5) (STK-1) (Aurora-B) Length = 345 Score = 36.6 bits (83), Expect = 0.053 Identities = 19/65 (29%), Positives = 32/65 (49%), Gaps = 3/65 (4%) Frame = +1 Query: 319 NFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVF---NLEMQGAERSFLSECEALRSVQHR 489 NF LGKG +G VY + + + VA+K+ +E +G E E E ++H Sbjct: 81 NFEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQIEKEGVEHQLRREIEIQAHLKHP 140 Query: 490 NLVSI 504 N++ + Sbjct: 141 NILQL 145
>AURKB_RAT (O55099) Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-| and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora-B) Length = 343 Score = 36.6 bits (83), Expect = 0.053 Identities = 19/65 (29%), Positives = 32/65 (49%), Gaps = 3/65 (4%) Frame = +1 Query: 319 NFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVF---NLEMQGAERSFLSECEALRSVQHR 489 NF LGKG +G VY + + + VA+K+ +E +G E E E ++H Sbjct: 79 NFEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQIEKEGVEHQLRREIEIQAHLKHP 138 Query: 490 NLVSI 504 N++ + Sbjct: 139 NILQL 143
>CDC2_RANDY (Q9W739) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 302 Score = 36.6 bits (83), Expect = 0.053 Identities = 24/85 (28%), Positives = 44/85 (51%), Gaps = 2/85 (2%) Frame = +1 Query: 322 FSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNL--EMQGAERSFLSECEALRSVQHRNL 495 +++ +G+G+YG VY+G VA+K L E +G + + E L+ +QH N+ Sbjct: 4 YAKIEKIGEGTYGVVYKGVHKATGQIVAMKKIRLENEEEGVPSTAIREISLLKELQHPNI 63 Query: 496 VSIITACSTIDSDGSAFRALIYEFM 570 V ++ + D + LI+EF+ Sbjct: 64 VCLL---DVLMQDSRLY--LIFEFL 83
>CDC2_CARAU (P51958) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 302 Score = 36.6 bits (83), Expect = 0.053 Identities = 19/58 (32%), Positives = 33/58 (56%), Gaps = 2/58 (3%) Frame = +1 Query: 340 LGKGSYGTVYRGKLVQHKLEVAVKVFNLEM--QGAERSFLSECEALRSVQHRNLVSII 507 +G+G+YG VY+G+ VA+K LE +G + + E L+ +QH N+V ++ Sbjct: 10 IGEGTYGVVYKGRNKTTGQVVAMKKIRLESEEEGVPSTAVREISLLKELQHPNVVRLL 67
>CDC2_VIGUN (P52389) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 36.6 bits (83), Expect = 0.053 Identities = 18/65 (27%), Positives = 35/65 (53%), Gaps = 2/65 (3%) Frame = +1 Query: 316 KNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQ--GAERSFLSECEALRSVQHR 489 + + + +G+G+YG VY+ + +A+K LE + G + + E L+ +QHR Sbjct: 2 EQYEKVEKIGEGTYGVVYKARDRVTDETIALKKIRLEQEDEGVPSTAIREISLLKEMQHR 61 Query: 490 NLVSI 504 N+V + Sbjct: 62 NIVRL 66
>BMR1B_HUMAN (O00238) Bone morphogenetic protein receptor type IB precursor (EC| 2.7.11.30) (CDw293 antigen) Length = 502 Score = 36.6 bits (83), Expect = 0.053 Identities = 42/145 (28%), Positives = 61/145 (42%), Gaps = 22/145 (15%) Frame = +1 Query: 145 RYYLIRVLIPLFGFMSLVLLVYFLVLERKMRRTRYESEAPLGEHF--PKVSYNDLVEATK 318 R LI V + + ++L YF +R+ R RY E + P S DL+E ++ Sbjct: 126 RALLISVTVCSLLLVLIILFCYFRY-KRQETRPRYSIGLEQDETYIPPGESLRDLIEQSQ 184 Query: 319 NFSESNLL------------------GKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAER 444 + + L GKG YG V+ GK K VAVKVF E Sbjct: 185 SSGSGSGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMGKWRGEK--VAVKVF---FTTEEA 239 Query: 445 SFLSECEALRSV--QHRNLVSIITA 513 S+ E E ++V +H N++ I A Sbjct: 240 SWFRETEIYQTVLMRHENILGFIAA 264
>ATG1_CRYNE (Q5K8D3) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 988 Score = 36.6 bits (83), Expect = 0.053 Identities = 21/77 (27%), Positives = 42/77 (54%), Gaps = 2/77 (2%) Frame = +1 Query: 307 EATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAE--RSFLSECEALRSV 480 E N+ +G+GS+ TVY+G + ++ +A+K + + ++ + SE L+ + Sbjct: 22 ERIGNYVVGAEIGRGSFATVYKGYRSKTRVPIAIKAVSRQKLTSKLLENLESEINILKVI 81 Query: 481 QHRNLVSIITACSTIDS 531 HRN+V+ +T C D+ Sbjct: 82 NHRNIVA-LTDCFKNDT 97
>STE20_YEAST (Q03497) Serine/threonine-protein kinase STE20 (EC 2.7.11.1)| Length = 939 Score = 36.6 bits (83), Expect = 0.053 Identities = 21/76 (27%), Positives = 37/76 (48%) Frame = +1 Query: 280 PKVSYNDLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSE 459 P Y +LV+ +G+G+ G VY + + VA+K NLE Q + ++E Sbjct: 616 PSTKYANLVK----------IGQGASGGVYTAYEIGTNVSVAIKQMNLEKQPKKELIINE 665 Query: 460 CEALRSVQHRNLVSII 507 ++ +H N+V+ I Sbjct: 666 ILVMKGSKHPNIVNFI 681
>CDC2_EMENI (Q00646) Cell division control protein 2 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent protein kinase) Length = 323 Score = 36.6 bits (83), Expect = 0.053 Identities = 23/88 (26%), Positives = 47/88 (53%), Gaps = 3/88 (3%) Frame = +1 Query: 316 KNFSESNLLGKGSYGTVYRGKLVQHKLE-VAVKVFNLEM--QGAERSFLSECEALRSVQH 486 +N+ + +G+G+YG VY+ + + H VA+K LE +G + + E L+ + Sbjct: 2 ENYQKIEKIGEGTYGVVYKARELTHPNRIVALKKIRLEAEDEGVPSTAIREISLLKEMND 61 Query: 487 RNLVSIITACSTIDSDGSAFRALIYEFM 570 N+V ++ + + +DG L++EF+ Sbjct: 62 PNIVRLL---NIVHADGHKL-YLVFEFL 85
>BUR1_ASHGO (Q75D46) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 753 Score = 36.6 bits (83), Expect = 0.053 Identities = 22/69 (31%), Positives = 38/69 (55%), Gaps = 6/69 (8%) Frame = +1 Query: 319 NFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQG------AERSFLSECEALRSV 480 N+ E LG+G++G VYRG + + +VA+K ++ + A+R E L+ + Sbjct: 55 NYKEEKKLGQGTFGEVYRGVHLATQRQVAMKKILVKTENDLFPITAQR----EITILKRL 110 Query: 481 QHRNLVSII 507 HRN+V +I Sbjct: 111 NHRNVVQLI 119
>NTRK3_PIG (P24786) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C) Length = 825 Score = 36.6 bits (83), Expect = 0.053 Identities = 24/85 (28%), Positives = 40/85 (47%), Gaps = 5/85 (5%) Frame = +1 Query: 340 LGKGSYGTVYRGKL-----VQHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRNLVSI 504 LG+G++G V+ + + K+ VAVK A + F E E L ++QH ++V Sbjct: 544 LGEGAFGKVFLAECYNLSPTKVKMLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKF 603 Query: 505 ITACSTIDSDGSAFRALIYEFMPKG 579 C DG +++E+M G Sbjct: 604 YGVC----GDGDPL-IMVFEYMKHG 623
>KSG9_ARATH (Q39012) Shaggy-related protein kinase iota (EC 2.7.11.1)| (ASK-iota) Length = 407 Score = 36.2 bits (82), Expect = 0.070 Identities = 21/88 (23%), Positives = 44/88 (50%) Frame = +1 Query: 313 TKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRN 492 T ++ ++G GS+G V++ K ++ VA+K + + R E + +R + H N Sbjct: 67 TISYMAERVVGTGSFGIVFQAKCLETGESVAIKKVLQDRRYKNR----ELQLMRPMDHPN 122 Query: 493 LVSIITACSTIDSDGSAFRALIYEFMPK 576 ++S+ + S F L+ E++P+ Sbjct: 123 VISLKHCFFSTTSRDELFLNLVMEYVPE 150
>E2AK1_SCHPO (O13889) Eukaryotic translation initiation factor 2-alpha kinase 1| (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor 1) Length = 704 Score = 36.2 bits (82), Expect = 0.070 Identities = 20/67 (29%), Positives = 33/67 (49%), Gaps = 2/67 (2%) Frame = +1 Query: 319 NFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERS--FLSECEALRSVQHRN 492 +F E LLGKG YG+VY+ + +E A+K L ++ S E L + H N Sbjct: 223 DFEELELLGKGGYGSVYKARNKFDGVEYALKKIPLRLRSFSTSSNIFRESRTLARLNHPN 282 Query: 493 LVSIITA 513 ++ ++ Sbjct: 283 VIRFFSS 289
>TBK1_MOUSE (Q9WUN2) Serine/threonine-protein kinase TBK1 (EC 2.7.11.1)| (TANK-binding kinase 1) (T2K) Length = 729 Score = 36.2 bits (82), Expect = 0.070 Identities = 25/84 (29%), Positives = 43/84 (51%), Gaps = 1/84 (1%) Frame = +1 Query: 331 SNLLGKGSYGTVYRGKLVQHKLEVAVKVF-NLEMQGAERSFLSECEALRSVQHRNLVSII 507 S++LG+G+ V+RG+ + AVKVF N+ + E E L+ + H+N+V + Sbjct: 12 SDILGQGATANVFRGRHKKTGDLYAVKVFNNISFLRPVDVQMREFEVLKKLNHKNIVKLF 71 Query: 508 TACSTIDSDGSAFRALIYEFMPKG 579 + + + + LI EF P G Sbjct: 72 ---AIEEETTTRHKVLIMEFCPCG 92
>PEF1_SCHPO (O74456) Serine/threonine-protein kinase pef1 (EC 2.7.11.22)| (Cyclin-dependent kinase pef1) (PHO85 homolog) Length = 288 Score = 36.2 bits (82), Expect = 0.070 Identities = 22/87 (25%), Positives = 44/87 (50%), Gaps = 1/87 (1%) Frame = +1 Query: 319 NFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEM-QGAERSFLSECEALRSVQHRNL 495 N+ LG+G+Y VY+G+ VA+KV ++ +G + + E ++ ++H N+ Sbjct: 2 NYQRLEKLGEGTYAHVYKGQNRVTGEIVALKVIRIDADEGTPSTAIREISLMKELRHPNI 61 Query: 496 VSIITACSTIDSDGSAFRALIYEFMPK 576 +S+ T + L++E+M K Sbjct: 62 MSLSDVLQTENK-----LMLVFEYMEK 83
>CDC2_RAT (P39951) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 36.2 bits (82), Expect = 0.070 Identities = 19/57 (33%), Positives = 33/57 (57%), Gaps = 2/57 (3%) Frame = +1 Query: 340 LGKGSYGTVYRGKLVQHKLEVAVKVFNLEM--QGAERSFLSECEALRSVQHRNLVSI 504 +G+G+YG VY+G+ VA+K LE +G + + E L+ ++H N+VS+ Sbjct: 10 IGEGTYGVVYKGRHRTTGQIVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSL 66
>CDC2_AJECA (P54119) Cell division control protein 2 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent protein kinase) Length = 324 Score = 36.2 bits (82), Expect = 0.070 Identities = 23/88 (26%), Positives = 47/88 (53%), Gaps = 3/88 (3%) Frame = +1 Query: 316 KNFSESNLLGKGSYGTVYRGKLVQHKLE-VAVKVFNLEM--QGAERSFLSECEALRSVQH 486 +N+ + +G+G+YG VY+ + + H VA+K LE +G + + E L+ + Sbjct: 2 ENYQKIEKIGEGTYGVVYKARDLTHPNRIVALKKIRLEAEDEGVPSTAIREISLLKEMHD 61 Query: 487 RNLVSIITACSTIDSDGSAFRALIYEFM 570 N+V ++ + + +DG L++EF+ Sbjct: 62 PNIVRLL---NIVHADGHKL-YLVFEFL 85
>PAK2_RAT (Q64303) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) (Gamma-PAK) (p62-PAK) Length = 524 Score = 36.2 bits (82), Expect = 0.070 Identities = 17/64 (26%), Positives = 36/64 (56%) Frame = +1 Query: 316 KNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRNL 495 K ++ +G+G+ GTV+ V EVA+K NL+ Q + ++E ++ +++ N+ Sbjct: 247 KKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKELKNPNI 306 Query: 496 VSII 507 V+ + Sbjct: 307 VNFL 310
>PAK2_MOUSE (Q8CIN4) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) Length = 524 Score = 36.2 bits (82), Expect = 0.070 Identities = 17/64 (26%), Positives = 36/64 (56%) Frame = +1 Query: 316 KNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRNL 495 K ++ +G+G+ GTV+ V EVA+K NL+ Q + ++E ++ +++ N+ Sbjct: 247 KKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKELKNPNI 306 Query: 496 VSII 507 V+ + Sbjct: 307 VNFL 310
>PAK2_HUMAN (Q13177) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) (PAK65) (Gamma-PAK) (S6/H4 kinase) Length = 524 Score = 36.2 bits (82), Expect = 0.070 Identities = 17/64 (26%), Positives = 36/64 (56%) Frame = +1 Query: 316 KNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRNL 495 K ++ +G+G+ GTV+ V EVA+K NL+ Q + ++E ++ +++ N+ Sbjct: 247 KKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKELKNPNI 306 Query: 496 VSII 507 V+ + Sbjct: 307 VNFL 310
>GSK3H_DROME (P83101) Putative glycogen synthase kinase-3 homolog (EC 2.7.11.26)| (GSK-3) (Protein gasket) Length = 501 Score = 36.2 bits (82), Expect = 0.070 Identities = 20/87 (22%), Positives = 48/87 (55%), Gaps = 1/87 (1%) Frame = +1 Query: 319 NFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRNLV 498 +++++ ++G GS+G V++ K+V VA+K + + R E + +R ++H N++ Sbjct: 32 SYTDAKVVGNGSFGVVFQAKMVPSNEMVAIKKVLQDRRFKNR----ELQIMRKLRHDNII 87 Query: 499 SI-ITACSTIDSDGSAFRALIYEFMPK 576 ++ S+ + + L+ EF+P+ Sbjct: 88 TLKWFFFSSGEKRDEVYLNLVMEFLPE 114
>CDK9_HUMAN (P50750) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) (Serine/threonine-protein kinase PITALRE) (C-2K) (Cell division cycle 2-like protein kinase 4) Length = 372 Score = 36.2 bits (82), Expect = 0.070 Identities = 21/76 (27%), Positives = 43/76 (56%), Gaps = 2/76 (2%) Frame = +1 Query: 340 LGKGSYGTVYRGKLVQHKLEVAVK--VFNLEMQGAERSFLSECEALRSVQHRNLVSIITA 513 +G+G++G V++ + + +VA+K + E +G + L E + L+ ++H N+V++I Sbjct: 25 IGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEI 84 Query: 514 CSTIDSDGSAFRALIY 561 C T S + + IY Sbjct: 85 CRTKASPYNRCKGSIY 100
>RIPK3_HUMAN (Q9Y572) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) Length = 518 Score = 36.2 bits (82), Expect = 0.070 Identities = 27/106 (25%), Positives = 48/106 (45%) Frame = +1 Query: 262 PLGEHFPKVSYNDLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAE 441 P G P VS +L L+GK +GTV+R + + +VAVK+ N Sbjct: 8 PSGAPAPLVSIEEL-------ENQELVGKDGFGTVFRAQHRKWGYDVAVKIVN------S 54 Query: 442 RSFLSECEALRSVQHRNLVSIITACSTIDSDGSAFRALIYEFMPKG 579 ++ E +A+ S+ + ++ + ++ D AL+ +FM G Sbjct: 55 KAISREVKAMASLDNEFVLRLEGVIEKVNWDQDPKPALVTKFMENG 100
>CDK7_XENLA (P20911) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (40 kDa protein kinase) (P40 MO15) (CDC2/CDK2,4-activating kinase) Length = 352 Score = 36.2 bits (82), Expect = 0.070 Identities = 20/77 (25%), Positives = 37/77 (48%), Gaps = 5/77 (6%) Frame = +1 Query: 298 DLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNL-----EMQGAERSFLSEC 462 D+ K + + + LG+G + TVY+ + VA+K L G R+ L E Sbjct: 10 DVRSRAKQYEKLDFLGEGQFATVYKARDKNTDRIVAIKKIKLGHRAEANDGINRTALREI 69 Query: 463 EALRSVQHRNLVSIITA 513 + L+ + H N++ ++ A Sbjct: 70 KLLQELSHPNIIGLLDA 86
>UNC51_CAEEL (Q23023) Serine/threonine-protein kinase unc-51 (EC 2.7.11.1)| (Uncoordinated protein 51) Length = 856 Score = 36.2 bits (82), Expect = 0.070 Identities = 21/72 (29%), Positives = 39/72 (54%), Gaps = 5/72 (6%) Frame = +1 Query: 322 FSESNLLGKGSYGTVYRGKLVQH-KLEVAVKVFNLEMQGAERSFLSE----CEALRSVQH 486 +S+ +LLG G++ VYRG+ V + VA+K + ++ L++ + L S++H Sbjct: 9 YSKRDLLGHGAFAIVYRGRYVDRTDVPVAIKAIAKKNISKSKNLLTKEIKILKELSSLKH 68 Query: 487 RNLVSIITACST 522 NLV ++ T Sbjct: 69 ENLVGLLKCTET 80
>ATG1_KLULA (Q6CSX2) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 831 Score = 36.2 bits (82), Expect = 0.070 Identities = 21/77 (27%), Positives = 40/77 (51%), Gaps = 3/77 (3%) Frame = +1 Query: 313 TKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFN---LEMQGAERSFLSECEALRSVQ 483 T+N+S +GKGS+ VY+G ++ +A+K + L+ + + E L+ ++ Sbjct: 18 TENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSKLKNKKLLENLEVEIAILKKIK 77 Query: 484 HRNLVSIITACSTIDSD 534 H ++V +I C SD Sbjct: 78 HPHIVGLID-CERTSSD 93
>E2AK1_RABIT (P33279) Eukaryotic translation initiation factor 2-alpha kinase 1| (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Heme-controlled repressor) (HCR) (Hemin-sensitive initiation factor Length = 626 Score = 36.2 bits (82), Expect = 0.070 Identities = 26/71 (36%), Positives = 41/71 (57%), Gaps = 7/71 (9%) Frame = +1 Query: 322 FSESNLLGKGSYGTVYRGKLVQHKLE---VAVKVFNLEMQGAERS----FLSECEALRSV 480 F E ++LGKG YG VY+ V++KL+ A+K + ++GA ++ L E + L + Sbjct: 170 FEELSILGKGGYGRVYK---VRNKLDGQYYAIK--KILIKGATKTDCMKVLREVKVLAGL 224 Query: 481 QHRNLVSIITA 513 QH N+V TA Sbjct: 225 QHPNIVGYHTA 235
>TBK1_HUMAN (Q9UHD2) Serine/threonine-protein kinase TBK1 (EC 2.7.11.1)| (TANK-binding kinase 1) (T2K) (NF-kappa-B-activating kinase) Length = 729 Score = 35.8 bits (81), Expect = 0.091 Identities = 24/84 (28%), Positives = 43/84 (51%), Gaps = 1/84 (1%) Frame = +1 Query: 331 SNLLGKGSYGTVYRGKLVQHKLEVAVKVF-NLEMQGAERSFLSECEALRSVQHRNLVSII 507 S++LG+G+ V+RG+ + A+KVF N+ + E E L+ + H+N+V + Sbjct: 12 SDILGQGATANVFRGRHKKTGDLFAIKVFNNISFLRPVDVQMREFEVLKKLNHKNIVKLF 71 Query: 508 TACSTIDSDGSAFRALIYEFMPKG 579 + + + + LI EF P G Sbjct: 72 ---AIEEETTTRHKVLIMEFCPCG 92
>E2AK3_DROME (Q9NIV1) Eukaryotic translation initiation factor 2-alpha kinase| precursor (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (PERK) (PEK) (DmPEK) Length = 1162 Score = 35.8 bits (81), Expect = 0.091 Identities = 25/89 (28%), Positives = 38/89 (42%), Gaps = 1/89 (1%) Frame = +1 Query: 235 RRTRYESEAPLGEHFPKVSYNDLVEATKNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKV 414 +RT ES GEH+ +D F LG+G +G V+ K + A+K Sbjct: 620 QRTISESTTHSGEHYTSRFQSD-------FELMQCLGRGGFGVVFEAKNKLDENRYAIKR 672 Query: 415 FNL-EMQGAERSFLSECEALRSVQHRNLV 498 L + + + L E L S +H N+V Sbjct: 673 ITLPNKESSRQRVLREARTLASCEHHNIV 701
>CDK2_CARAU (P43450) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 35.8 bits (81), Expect = 0.091 Identities = 23/87 (26%), Positives = 44/87 (50%), Gaps = 2/87 (2%) Frame = +1 Query: 316 KNFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNL--EMQGAERSFLSECEALRSVQHR 489 ++F + +G+G+YG VY+ K VA+K L E +G + + E L+ + H Sbjct: 2 ESFQKVEKIGEGTYGVVYKAKNKVTGETVALKKIRLDTETEGVPSTAIREISLLKELNHP 61 Query: 490 NLVSIITACSTIDSDGSAFRALIYEFM 570 N+V + I ++ + L++EF+ Sbjct: 62 NIVKL---HDVIHTENKLY--LVFEFL 83
>SGG_DROME (P18431) Protein kinase shaggy (EC 2.7.11.1) (Protein zeste-white| 3) Length = 1067 Score = 35.8 bits (81), Expect = 0.091 Identities = 21/87 (24%), Positives = 47/87 (54%), Gaps = 1/87 (1%) Frame = +1 Query: 319 NFSESNLLGKGSYGTVYRGKLVQHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRNLV 498 +++++ ++G GS+G V++ KL VA+K + + R E + +R ++H N+V Sbjct: 606 SYTDTKVIGNGSFGVVFQAKLCDTGELVAIKKVLQDRRFKNR----ELQIMRKLEHCNIV 661 Query: 499 SII-TACSTIDSDGSAFRALIYEFMPK 576 ++ S+ + F L+ E++P+ Sbjct: 662 KLLYFFYSSGEKRDEVFLNLVLEYIPE 688
>CDC2_MOUSE (P11440) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 35.8 bits (81), Expect = 0.091 Identities = 19/57 (33%), Positives = 33/57 (57%), Gaps = 2/57 (3%) Frame = +1 Query: 340 LGKGSYGTVYRGKLVQHKLEVAVKVFNLEM--QGAERSFLSECEALRSVQHRNLVSI 504 +G+G+YG VY+G+ VA+K LE +G + + E L+ ++H N+VS+ Sbjct: 10 IGEGTYGVVYKGRHRVTGQIVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSL 66
>NTRK1_CHICK (Q91009) High affinity nerve growth factor receptor precursor (EC| 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (Trk-A) (Fragment) Length = 778 Score = 35.8 bits (81), Expect = 0.091 Identities = 24/85 (28%), Positives = 38/85 (44%), Gaps = 5/85 (5%) Frame = +1 Query: 340 LGKGSYGTVYRGKLV-----QHKLEVAVKVFNLEMQGAERSFLSECEALRSVQHRNLVSI 504 LG+G++G V+ + Q K VAVK + A F E E L +QH ++V Sbjct: 499 LGEGAFGKVFLAECSHLLPEQEKTLVAVKALKEVTENARLDFQREAELLTVLQHEHIVKF 558 Query: 505 ITACSTIDSDGSAFRALIYEFMPKG 579 C+ D +++E+M G Sbjct: 559 YGVCTEGDP-----LIMVFEYMKHG 578 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 84,995,350 Number of Sequences: 219361 Number of extensions: 1740155 Number of successful extensions: 5863 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 5610 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5777 length of database: 80,573,946 effective HSP length: 106 effective length of database: 57,321,680 effective search space used: 4929664480 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
