ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | baal6i06 |
|---|---|
| Clone Library Name | barley_pub |
>C97B3_ARATH (O23365) Cytochrome P450 97B3 (EC 1.14.-.-)| Length = 580 Score = 180 bits (457), Expect = 2e-45 Identities = 90/190 (47%), Positives = 130/190 (68%), Gaps = 8/190 (4%) Frame = +1 Query: 22 GXAIFLPLYDHFLTHGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFV 201 G +FL LYD FL HGG+++L GPK+FV++SDP IA+H+LR+N+ +Y KG+LAEILE + Sbjct: 96 GKPLFLSLYDWFLEHGGIYKLAFGPKAFVVISDPIIARHVLRENAFSYDKGVLAEILEPI 155 Query: 202 MGTGLIPADGEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEI---- 369 MG GLIPAD + W++RRRAI P+ H+ ++ M+ +F S ++ K +K E E Sbjct: 156 MGKGLIPADLDTWKLRRRAITPAFHKLYLEAMVKVFSDCSEKMILKSEKLIREKETSSGE 215 Query: 370 ----VEMESLFSRLTLDVIGKAVFNYDFDSLSYDNGMVEAVYVTLREAEMRSTSPIPTWK 537 +++E+ FS L LD+IG +VFNYDF S++ ++ +++AVY TL EAE RST P W Sbjct: 216 DTIELDLEAEFSSLALDIIGLSVFNYDFGSVTKESPVIKAVYGTLFEAEHRSTFYFPYWN 275 Query: 538 IPIWKDISPR 567 P + I PR Sbjct: 276 FPPARWIVPR 285
>C97B2_SOYBN (O48921) Cytochrome P450 97B2 (EC 1.14.-.-)| Length = 576 Score = 177 bits (450), Expect = 1e-44 Identities = 92/190 (48%), Positives = 128/190 (67%), Gaps = 8/190 (4%) Frame = +1 Query: 22 GXAIFLPLYDHFLTHGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFV 201 G +F LYD FL HG +++L GPK+FV+VSDP +A+HILR+N+ +Y KG+LA+ILE + Sbjct: 91 GRPLFFSLYDWFLEHGAVYKLAFGPKAFVVVSDPIVARHILRENAFSYDKGVLADILEPI 150 Query: 202 MGTGLIPADGEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGE----- 366 MG GLIPAD + W+ RRR I P+ H ++ M+ +F S R K +K EGE Sbjct: 151 MGKGLIPADLDTWKQRRRVIAPAFHNSYLEAMVKIFTTCSERTILKFNK-LLEGEGYDGP 209 Query: 367 ---IVEMESLFSRLTLDVIGKAVFNYDFDSLSYDNGMVEAVYVTLREAEMRSTSPIPTWK 537 +++E+ FS L LD+IG VFNYDF S++ ++ +++AVY TL EAE RST IP WK Sbjct: 210 DSIELDLEAEFSSLALDIIGLGVFNYDFGSVTKESPVIKAVYGTLFEAEHRSTFYIPYWK 269 Query: 538 IPIWKDISPR 567 IP+ + I PR Sbjct: 270 IPLARWIVPR 279
>C97B1_PEA (Q43078) Cytochrome P450 97B1 (EC 1.14.-.-) (P450 97A2)| Length = 552 Score = 174 bits (440), Expect = 2e-43 Identities = 90/187 (48%), Positives = 126/187 (67%), Gaps = 8/187 (4%) Frame = +1 Query: 31 IFLPLYDHFLTHGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGT 210 +F LYD FL HG +++L GPK+FV+VSDP +A+HILR+N+ +Y KG+LA+ILE +MG Sbjct: 103 LFFSLYDWFLEHGSVYKLAFGPKAFVVVSDPIVARHILRENAFSYDKGVLADILEPIMGK 162 Query: 211 GLIPADGEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGE-------- 366 GLIPAD E W+ RRR I P H ++ M+ LF S R K+++ EGE Sbjct: 163 GLIPADLETWKQRRRVIAPGFHTSYLEAMVQLFTSCSERTVLKVNE-LLEGEGRDGQKSV 221 Query: 367 IVEMESLFSRLTLDVIGKAVFNYDFDSLSYDNGMVEAVYVTLREAEMRSTSPIPTWKIPI 546 +++E+ FS L L++IG VFNYDF S++ ++ +++AVY TL EAE RST IP WK P+ Sbjct: 222 ELDLEAEFSNLALEIIGLGVFNYDFGSVTNESPVIKAVYGTLFEAEHRSTFYIPYWKFPL 281 Query: 547 WKDISPR 567 + I PR Sbjct: 282 ARWIVPR 288
>CP2H1_CHICK (P05180) Cytochrome P450 2H1 (EC 1.14.14.1) (CYPIIH1) (PB15) (P450| PCHP3) Length = 491 Score = 57.4 bits (137), Expect = 3e-08 Identities = 29/71 (40%), Positives = 45/71 (63%), Gaps = 1/71 (1%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYS-KGILAEILEFVMGTGLIPADGEVW 240 +G +F ++LGPK V++ DI K L DN +A+S +GIL I + GTG++ ++GE W Sbjct: 64 YGPIFTIHLGPKKIVVLYGYDIVKEALIDNGEAFSGRGILPLIEKLFKGTGIVTSNGETW 123 Query: 241 RVRRRAIVPSL 273 R RR + +L Sbjct: 124 RQLRRFALTTL 134
>CP4CU_BLAGE (Q964T1) Cytochrome P450 4c21 (EC 1.14.14.1) (CYPIVC21)| Length = 501 Score = 56.2 bits (134), Expect = 6e-08 Identities = 38/133 (28%), Positives = 61/133 (45%) Frame = +1 Query: 91 GPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVRRRAIVPS 270 G + FV +S P++ + +LR N++ K L ++ +GTGL+ + G W R+ I P+ Sbjct: 77 GNRPFVNISSPELIEVVLR-NTQLIDKAFLYDLFHSWLGTGLLTSSGAKWHQHRKIITPT 135 Query: 271 LHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVFNYDFDSL 450 H + I +F + S L KL K G + S LD+I + + Sbjct: 136 FHFSILEGFITIFAEKSEILVRKLQKEVGRGPFF-IRQYVSNCALDIICETAMGTSVN-- 192 Query: 451 SYDNGMVEAVYVT 489 + D G E YVT Sbjct: 193 AQDEGFSE--YVT 203
>CP4E3_DROME (Q9VL92) Cytochrome P450 4e3 (EC 1.14.-.-) (CYPIVE3)| Length = 526 Score = 55.5 bits (132), Expect = 1e-07 Identities = 35/146 (23%), Positives = 71/146 (48%), Gaps = 1/146 (0%) Frame = +1 Query: 88 LGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVRRRAIVP 267 +G S +++++P ++IL ++ + K + ++L +G GL+ + G W R+ I P Sbjct: 75 IGYSSHIVMTNPKQLEYIL-NSQQLIQKSTIYDLLHPWLGHGLLTSFGSKWHKHRKMITP 133 Query: 268 SLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVFNYDFDS 447 S H + + + + S + +L KA+A I++ + + LTLDVI ++ Sbjct: 134 SFHFNILQDFHEVMNENSAKFMTQLKKASAGDTIIDFQEHANYLTLDVICDTAMGVPINA 193 Query: 448 LSY-DNGMVEAVYVTLREAEMRSTSP 522 + D+ +V+A MR+ P Sbjct: 194 MEQRDSSIVQAFRDMCYNINMRAFHP 219
>C94A2_VICSA (P98188) Cytochrome P450 94A2 (EC 1.14.-.-) (P450-dependent fatty| acid omega-hydroxylase) Length = 513 Score = 54.7 bits (130), Expect = 2e-07 Identities = 34/116 (29%), Positives = 57/116 (49%), Gaps = 5/116 (4%) Frame = +1 Query: 106 VIVSDPDIAKHILRDNSKAYSKGI-LAEILEFVMGTGLIPADGEVWRVRRRAIVPSLH-- 276 V + P + +HILR N Y KG+ + + +G G+ ADGE W+ +R+ + Sbjct: 89 VFTAQPAVVQHILRTNFTCYGKGLTFYQSINDFLGDGIFNADGESWKFQRQISSHEFNTR 148 Query: 277 --QKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVFNYD 438 +KFV ++ + + S RL L +A+ ++ + + RLT D I F YD Sbjct: 149 SLRKFVETVVDV--ELSDRLVPVLSQASNSQTTLDFQDILQRLTFDNICMIAFGYD 202
>C13A7_CAEEL (Q27519) Putative cytochrome P450 CYP13A7 (EC 1.14.-.-)| Length = 518 Score = 54.3 bits (129), Expect = 2e-07 Identities = 35/153 (22%), Positives = 72/153 (47%), Gaps = 8/153 (5%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHI-LRDNSKAYSKGILAEILEFVMG-------TGLI 219 +G ++ + G + +++SDP+ + ++ Y + + A + G L+ Sbjct: 64 YGPVYGITEGVEKTLVISDPEFVHEVFVKQFDNFYGRKLTA-----IQGDPNKNKRVPLV 118 Query: 220 PADGEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRL 399 A G W+ R P+ K + +++G ++ L L+KA+AEG+ ++M + Sbjct: 119 AAQGHRWKRLRTLASPTFSNKSLRKIMGTVEESVTELVRSLEKASAEGKTLDMLEYYQEF 178 Query: 400 TLDVIGKAVFNYDFDSLSYDNGMVEAVYVTLRE 498 T+D+IGK + SL + N M++ V +E Sbjct: 179 TMDIIGKMAMGQE-KSLMFRNPMLDKVKTIFKE 210
>CP4F8_HUMAN (P98187) Cytochrome P450 4F8 (EC 1.14.14.1) (CYPIVF8)| Length = 520 Score = 53.9 bits (128), Expect = 3e-07 Identities = 34/120 (28%), Positives = 64/120 (53%), Gaps = 3/120 (2%) Frame = +1 Query: 88 LGPKSFVI-VSDPDIAKHILRDNSKAYSKGILA-EILEFVMGTGLIPADGEVWRVRRRAI 261 LGP + +I + PDI + ++ + K I+ + L+ +G GL+ + G+ WR RR + Sbjct: 92 LGPITPIINLCHPDIVRSVINTSDAITDKDIVFYKTLKPWLGDGLLLSVGDKWRHHRRLL 151 Query: 262 VPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGE-IVEMESLFSRLTLDVIGKAVFNYD 438 P+ H + I +F K++ + K + A EG +++ S +TLD + K +F++D Sbjct: 152 TPAFHFNILKPYIKIFSKSANIMHAKWQRLAMEGSTCLDVFEHISLMTLDSLQKCIFSFD 211
>C6A20_DROME (Q9V773) Probable cytochrome P450 6a20 (EC 1.14.-.-) (CYPVIA20)| Length = 501 Score = 53.5 bits (127), Expect = 4e-07 Identities = 33/121 (27%), Positives = 58/121 (47%), Gaps = 2/121 (1%) Frame = +1 Query: 97 KSFVIVSDPDIAKHIL-RDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVRRRAIVPSL 273 K V+V+D D AK +L R+ K + +G+ + + L+ DG+ W+ R+ + P+ Sbjct: 79 KRMVVVTDIDFAKTVLIREFDKFHDRGVFHNERDDPLSANLVNIDGQKWKTLRQKLTPTF 138 Query: 274 HQKFVTEMIGLFGKASGRLCEKL-DKAAAEGEIVEMESLFSRLTLDVIGKAVFNYDFDSL 450 + M L + A+A+ + +E+ ++ +R T DVIG F D SL Sbjct: 139 TSGKMKTMFPTILTVGDELIRVFGETASADSDSMEITNVVARFTADVIGSCAFGLDCHSL 198 Query: 451 S 453 S Sbjct: 199 S 199
>CP6D3_MUSDO (Q964Q7) Cytochrome P450 6d3 (EC 1.14.-.-) (CYPVID3) (Pyrethroid| resistance cytochrome P450) Length = 520 Score = 53.5 bits (127), Expect = 4e-07 Identities = 34/149 (22%), Positives = 68/149 (45%), Gaps = 3/149 (2%) Frame = +1 Query: 16 RPGXAIFLPLYDHFLTHGGLFRLNLGPKSFVIVSDPDIAKHILR-DNSKAYSKGILAEIL 192 RP + LY+ F + + L K +++ D ++A+ IL D + + +GI + Sbjct: 49 RPFGLVMYDLYEKFQEQ--VVGIYLFFKPALLIRDAELARQILTSDFNSFHDRGIYVDEK 106 Query: 193 EFVMGTGLIPADGEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGE-- 366 M L +G+ WR R + PS + M +L E L+ +G+ Sbjct: 107 NDPMSANLFALEGQSWRTLRMKLTPSFSSGKLKGMFETVDDVGNKLLEYLNNQLKDGQTH 166 Query: 367 IVEMESLFSRLTLDVIGKAVFNYDFDSLS 453 +++++S+ + +D+IG +F + DS + Sbjct: 167 VLDIKSILTTYAIDIIGSVIFGLEIDSFT 195
>CP4S3_DROME (Q9VXY0) Probable cytochrome P450 4s3 (EC 1.14.-.-) (CYPIVS3)| Length = 495 Score = 53.1 bits (126), Expect = 5e-07 Identities = 42/153 (27%), Positives = 69/153 (45%), Gaps = 1/153 (0%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWR 243 HG +FR+ G V+ +DP+ K +L N++ +K E+LE +G GL+ GE W Sbjct: 63 HGPVFRIWFGKDLMVMFTDPEDIKQLL-GNNQLLTKSRNYELLEPWLGKGLLTNGGESWH 121 Query: 244 VRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKA 423 RR+ + P H + ++E + L +L + A GE ++ + LD I + Sbjct: 122 RRRKLLTPGFHFRILSEFKEPMEENCRILVRRL-RTKANGESFDIYPYITLFALDAICET 180 Query: 424 VFNY-DFDSLSYDNGMVEAVYVTLREAEMRSTS 519 L D+ V+AV R +S S Sbjct: 181 AMGIKKHAQLQSDSEYVQAVQSICRVMHKQSFS 213
>CP2BF_RAT (Q64583) Cytochrome P450 2B15 (EC 1.14.14.1) (CYPIIB15)| Length = 495 Score = 53.1 bits (126), Expect = 5e-07 Identities = 39/133 (29%), Positives = 71/133 (53%), Gaps = 6/133 (4%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYS-KGILAEILEFVMGTGLIPADGEVW 240 +G +F ++LGP+ VI+ D + L D ++A+S +G +A + V G G+I A+GE W Sbjct: 63 YGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERW 122 Query: 241 RVRRRAIVPSLH-----QKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTL 405 ++ RR + ++ ++ V E I + + L E+L K +G ++ S+F + Sbjct: 123 KILRRFSLVTMRNFGMGKRSVEERI---KEEAQCLVEELKK--YKGALLNPTSIFQSIAA 177 Query: 406 DVIGKAVFNYDFD 444 ++I VF FD Sbjct: 178 NIICSIVFGERFD 190
>CP4C1_BLADI (P29981) Cytochrome P450 4C1 (EC 1.14.14.1) (CYPIVC1)| Length = 511 Score = 52.8 bits (125), Expect = 7e-07 Identities = 39/154 (25%), Positives = 73/154 (47%), Gaps = 1/154 (0%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWR 243 +G L+R+ GP + V ++ P+ + ILRD +K K ++ + +G GL+ G W Sbjct: 70 YGPLYRIWAGPIAQVGLTRPEHVELILRD-TKHIDKSLVYSFIRPWLGEGLLTGTGAKWH 128 Query: 244 VRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKA 423 R+ I P+ H K + + +F + S L +KL ++ G+ ++ + LD+I + Sbjct: 129 SHRKMITPTFHFKILDIFVDVFVEKSEILVKKL-QSKVGGKDFDIYPFITHCALDIICET 187 Query: 424 VFNYDFDSL-SYDNGMVEAVYVTLREAEMRSTSP 522 ++ ++ V+AVY RS P Sbjct: 188 AMGIQMNAQEESESEYVKAVYEISELTMQRSVRP 221
>C4D21_DROME (Q9VLZ7) Probable cytochrome P450 4d21 (EC 1.14.-.-) (CYPIVD21)| Length = 511 Score = 52.8 bits (125), Expect = 7e-07 Identities = 43/171 (25%), Positives = 70/171 (40%), Gaps = 5/171 (2%) Frame = +1 Query: 49 DHFLTHGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPAD 228 D+F +G FRL + + + D + IL +S K L L +G GL+ + Sbjct: 62 DYFNKYGKTFRLWILGECLIYTKDLKYFESIL-SSSTLLKKAHLYRFLRDFLGDGLLLST 120 Query: 229 GEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLD 408 G W RR+ + P+ H K + + + + SG + EKL A V++ S LD Sbjct: 121 GNKWTSRRKVLAPAFHFKCLENFVEIMDRNSGIMVEKLKNYADGKTCVDLFKFVSLEALD 180 Query: 409 V-----IGKAVFNYDFDSLSYDNGMVEAVYVTLREAEMRSTSPIPTWKIPI 546 V +G V + + Y + VY+ + S S W P+ Sbjct: 181 VTTETAMGVQVNAQNEPNFPYTKALKSVVYI--ESKRLASVSMRYNWLFPL 229
>CP4E1_DROME (Q9V4T5) Probable cytochrome P450 4e1 (EC 1.14.-.-) (CYPIVE1)| Length = 531 Score = 52.8 bits (125), Expect = 7e-07 Identities = 39/155 (25%), Positives = 72/155 (46%), Gaps = 1/155 (0%) Frame = +1 Query: 76 FRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVRRR 255 FR +G S ++V++P + IL + SK + ++ +G GL+ + G W R+ Sbjct: 71 FRYWIGYYSNIMVTNPKYMEFILSSQT-LISKSDVYDLTHPWLGLGLLTSTGSKWHKHRK 129 Query: 256 AIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVFNY 435 I P+ H + + + + S + ++L K A G I + + LTLDVI Sbjct: 130 MITPAFHFNILQDFHEVMNENSTKFIDQLKKVADGGNIFDFQEEAHYLTLDVICDTAMGV 189 Query: 436 DFDSL-SYDNGMVEAVYVTLREAEMRSTSPIPTWK 537 +++ + + +V+A +MR+ SP WK Sbjct: 190 SINAMENRSSSVVQAFKDITYTIKMRAFSP---WK 221
>CP4A7_RABIT (P14581) Cytochrome P450 4A7 precursor (EC 1.14.15.3) (CYPIVA7)| (Lauric acid omega-hydroxylase) (P450-KA-2) Length = 511 Score = 52.4 bits (124), Expect = 9e-07 Identities = 35/116 (30%), Positives = 58/116 (50%), Gaps = 1/116 (0%) Frame = +1 Query: 91 GPKSFVIVSDPDIAKHIL-RDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVRRRAIVP 267 G + F+I DPD K IL R + KA + L +G GL+ +G+ W RR + P Sbjct: 92 GSELFLICYDPDYMKTILGRSDPKAR---VSYSFLAPWIGYGLLLLEGQTWFQHRRMLTP 148 Query: 268 SLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVFNY 435 + H + +GL + + +KL+K A + +E+ S +TL+ I K F++ Sbjct: 149 AFHYDILKPYVGLMVDSVQVMLDKLEKLARKDAPLEIYEHVSLMTLETIMKCAFSH 204
>CP2H2_CHICK (P20678) Cytochrome P450 2H2 (EC 1.14.14.1) (CYPIIH2) (P450 PCHP7)| Length = 491 Score = 51.6 bits (122), Expect = 2e-06 Identities = 26/71 (36%), Positives = 43/71 (60%), Gaps = 1/71 (1%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYS-KGILAEILEFVMGTGLIPADGEVW 240 +G +F ++LGPK V++ D+ K L DN +A+S +G L + GTG++ ++GE W Sbjct: 64 YGPIFTIHLGPKKVVVLYGYDVVKEALIDNGEAFSGRGNLPLFEKVFKGTGIVTSNGESW 123 Query: 241 RVRRRAIVPSL 273 R RR + +L Sbjct: 124 RQMRRFALTTL 134
>THAS_RAT (P49430) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| Length = 533 Score = 51.6 bits (122), Expect = 2e-06 Identities = 28/128 (21%), Positives = 61/128 (47%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWR 243 +G L LG + ++++SDPD+ K +L +N +S + + + ++ ++ W Sbjct: 74 YGPLCGYYLGRRMYIVISDPDMIKEVLVENFSNFSNRMASGLEPKLIADSVLMLRDRRWE 133 Query: 244 VRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKA 423 R A++ + + + EM L +A L L +AA G+ +++ + T +V+ Sbjct: 134 EVRGALMSAFSPEKLNEMTPLISQACELLLSHLKHSAASGDAFDIQRCYCCFTTNVVASV 193 Query: 424 VFNYDFDS 447 F + +S Sbjct: 194 AFGIEVNS 201
>CP4F4_RAT (P51869) Cytochrome P450 4F4 (EC 1.14.14.1) (CYPIVF4)| Length = 522 Score = 51.6 bits (122), Expect = 2e-06 Identities = 34/134 (25%), Positives = 65/134 (48%), Gaps = 3/134 (2%) Frame = +1 Query: 88 LGP-KSFVIVSDPDIAKHILRDN-SKAYSKGILAEILEFVMGTGLIPADGEVWRVRRRAI 261 LGP + + PD+ + +L + S A + I L+ +G GL+ +DG+ W RR + Sbjct: 92 LGPILPIITLCHPDVIRSVLSASASVALKEVIFYSFLKPWLGDGLLLSDGDKWSCHRRML 151 Query: 262 VPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEI-VEMESLFSRLTLDVIGKAVFNYD 438 P+ H + + +F ++ + K A+ G ++M S +TLD + K VF++D Sbjct: 152 TPAFHFNILKPYVKIFNDSTNIMHAKWQDLASGGSARLDMFKNISLMTLDSLQKCVFSFD 211 Query: 439 FDSLSYDNGMVEAV 480 + + + A+ Sbjct: 212 SNCQEKPSEYISAI 225
>CP3AO_SHEEP (Q29496) Cytochrome P450 3A24 (EC 1.14.14.1) (CYPIIIA24)| Length = 503 Score = 51.2 bits (121), Expect = 2e-06 Identities = 34/134 (25%), Positives = 63/134 (47%), Gaps = 2/134 (1%) Frame = +1 Query: 55 FLTHGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILE--FVMGTGLIPAD 228 F +G ++ + G + ++++DPD+ K +L + YS + +M + A+ Sbjct: 65 FKKYGKMWGVFEGKQPLLVITDPDVIKTVLV--KECYSVFTNRRVFGPMGIMKNAVSVAE 122 Query: 229 GEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLD 408 E W+ R + P+ + +M + GK L L K A +G+ V M+ +F ++D Sbjct: 123 DEQWKRIRTLLSPTFTSGKLKDMFPIIGKYGDVLVRNLRKEAEKGKSVNMKDIFGAYSMD 182 Query: 409 VIGKAVFNYDFDSL 450 VI F + DSL Sbjct: 183 VITSTSFGVNIDSL 196
>C4AE1_DROME (O46054) Cytochrome P450 4ae1 (EC 1.14.-.-) (CYPIVAE1)| Length = 496 Score = 51.2 bits (121), Expect = 2e-06 Identities = 28/104 (26%), Positives = 50/104 (48%) Frame = +1 Query: 169 KGILAEILEFVMGTGLIPADGEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDK 348 KG + L +G GL+ + G+ W R+ I P+ H + + + +F + S L E+L Sbjct: 102 KGTMYFALRGWLGDGLLLSRGKEWHTMRKIITPTFHFSILEQFVEVFDRQSSILVERLRT 161 Query: 349 AAAEGEIVEMESLFSRLTLDVIGKAVFNYDFDSLSYDNGMVEAV 480 + E+V + L LD+I + + D+ D+ +V AV Sbjct: 162 LSYGNEVVNIYPLVGLAALDIITETAMGVNVDAQGADSEVVHAV 205
>C6A14_DROME (Q9V4U7) Probable cytochrome P450 6a14 (EC 1.14.-.-) (CYPVIA14)| Length = 509 Score = 50.8 bits (120), Expect = 3e-06 Identities = 36/141 (25%), Positives = 62/141 (43%), Gaps = 5/141 (3%) Frame = +1 Query: 43 LYDHFLTHGGLFRLNLGPKSFVIVSDPDIAKHIL-RDNSKAYSKGILAEILEFVMGTGLI 219 +Y F G + + K +++D D K ++ +D S +G + + L Sbjct: 59 IYKKFKGQGPIAGMYTFFKRTALITDLDFIKQVMIKDFSYFQDRGAFTNPRDDPLTGHLF 118 Query: 220 PADGEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEI----VEMESL 387 +GE WR R + P + +M + RL + +DKA E ++ VE++ L Sbjct: 119 ALEGEEWRAMRHKLTPVFTSGKIKQMSKVIVDVGLRLGDAMDKAVKEAKVEEGNVEIKDL 178 Query: 388 FSRLTLDVIGKAVFNYDFDSL 450 +R T DVIG F + +SL Sbjct: 179 CARFTTDVIGSCAFGLECNSL 199
>CP4A4_RABIT (P10611) Cytochrome P450 4A4 precursor (EC 1.14.14.1) (CYPIVA4)| (Prostaglandin omega-hydroxylase) (P450-P-2) Length = 510 Score = 50.8 bits (120), Expect = 3e-06 Identities = 33/116 (28%), Positives = 59/116 (50%), Gaps = 1/116 (0%) Frame = +1 Query: 91 GPKSFVIVSDPDIAKHIL-RDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVRRRAIVP 267 G K+ ++V DPD K IL R + KA +++ +G GL+ DG+ W RR + P Sbjct: 92 GNKARLLVYDPDYLKVILGRSDPKAPRN---YKLMTPWIGYGLLLLDGQTWFQHRRMLTP 148 Query: 268 SLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVFNY 435 + H + +GL + + ++ ++ ++ +E+ S +TLD I K F+Y Sbjct: 149 AFHYDILKPYVGLMVDSVQIMLDRWEQLISQDSSLEIFQHVSLMTLDTIMKCAFSY 204
>CP311_DROME (Q9VYQ7) Probable cytochrome P450 311a1 (EC 1.14.-.-) (CYPCCCXIA1)| Length = 483 Score = 50.4 bits (119), Expect = 3e-06 Identities = 49/193 (25%), Positives = 88/193 (45%), Gaps = 9/193 (4%) Frame = +1 Query: 7 GRWRPGXA--IFLPLYDHFLTHGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGIL 180 G+ RP +F L D F G +RL LGP+ +V + + + L D + + + Sbjct: 45 GKLRPEYIFLVFTELRDRF---GATYRLRLGPQLWVFLHSAEETRQALHDPTLRKADTFM 101 Query: 181 AEILEFVMGTGLIPADGEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAE 360 LE ++G GL+ + G W +RR + P+ + + G RL +L A Sbjct: 102 Q--LEPLIGNGLLISHGAHWTRQRRLLTPAFQPQLLRSFAPAIGGHVERLVGRL--GATR 157 Query: 361 GEIVEM-ESLFSRLTLDVIGKAVFNYDFDSLSYDNG-MVEAVYVTLREAEMRSTSPI--P 528 G +E+ E LF+ L LD I D+ S D+ +++A +++ + R +P+ Sbjct: 158 GAFLEVTEPLFACL-LDAIVDTSMGAQLDTQSVDHSPIIQAFHLSSKLLFKRMINPLLSS 216 Query: 529 TW---KIPIWKDI 558 W + +W+D+ Sbjct: 217 DWIFQRTQLWRDL 229
>CP4V2_HUMAN (Q6ZWL3) Cytochrome P450 4V2 (EC 1.14.-.-)| Length = 525 Score = 50.4 bits (119), Expect = 3e-06 Identities = 38/147 (25%), Positives = 68/147 (46%), Gaps = 1/147 (0%) Frame = +1 Query: 46 YDHFLTHGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPA 225 Y H L +L +GP V + + + + IL +SK K + + LE +G GL+ + Sbjct: 80 YTEEYRHMPLLKLWVGPVPMVALYNAENVEVILT-SSKQIDKSSMYKFLEPWLGLGLLTS 138 Query: 226 DGEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTL 405 G WR RR+ + P+ H + + + + + + L +KL+K + E + L Sbjct: 139 TGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQ-EAFNCFFYITLCAL 197 Query: 406 DVIGKAVFNYDFDSLSYDNG-MVEAVY 483 D+I + + + S D+ V AVY Sbjct: 198 DIICETAMGKNIGAQSNDDSEYVRAVY 224
>CP134_DROME (Q9VG40) Probable cytochrome P450 313a4 (EC 1.14.-.-)| (CYPCCCXIIIA4) Length = 478 Score = 50.4 bits (119), Expect = 3e-06 Identities = 36/147 (24%), Positives = 63/147 (42%), Gaps = 1/147 (0%) Frame = +1 Query: 1 GRGRWRPGXAIFLPLYDHFLT-HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGI 177 G W L + FL HG LGP F+IVSDP + + I + +KGI Sbjct: 42 GMAHWLMRREDILNAFGCFLDKHGPTIFSWLGPIPFMIVSDPQVVQDIFT-SPHCVNKGI 100 Query: 178 LAEILEFVMGTGLIPADGEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAA 357 + + ++ G GL W + R+ + P+ K + + +F + + L ++L+ Sbjct: 101 IYKAVDDGAGVGLFSLKDPRWSIHRKLLNPAFGHKVLLSFLPIFNRETALLLDQLEPLQD 160 Query: 358 EGEIVEMESLFSRLTLDVIGKAVFNYD 438 +GE ++ L TL + + D Sbjct: 161 DGE-KDLIPLLQSFTLGIATQTTMGSD 186
>C86A1_ARATH (P48422) Cytochrome P450 86A1 (EC 1.14.-.-) (CYPLXXXVI)| (P450-dependent fatty acid omega-hydroxylase) Length = 513 Score = 50.4 bits (119), Expect = 3e-06 Identities = 32/122 (26%), Positives = 57/122 (46%), Gaps = 3/122 (2%) Frame = +1 Query: 103 FVIVSDPDIAKHILRDNSKAYSKGIL-AEILEFVMGTGLIPADGEVWRVRRRAIVPSLHQ 279 + + P +HIL+ Y KG + ++G G+ +DG+ W ++R+ Sbjct: 84 YTVTCHPKNVEHILKTRFDNYPKGPMWRAAFHDLLGQGIFNSDGDTWLMQRKTAALEFTT 143 Query: 280 KFVTEMIGLF--GKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVFNYDFDSLS 453 + + + + + G RL LD+A + V+++ LF RLT D I F D ++LS Sbjct: 144 RTLRQAMARWVNGTIKNRLWLILDRAVQNNKPVDLQDLFLRLTFDNICGLTFGKDPETLS 203 Query: 454 YD 459 D Sbjct: 204 LD 205
>THAS_HUMAN (P24557) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| Length = 533 Score = 50.1 bits (118), Expect = 4e-06 Identities = 32/129 (24%), Positives = 62/129 (48%), Gaps = 1/129 (0%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFV-MGTGLIPADGEVW 240 +G L LG + F+++S+PD+ K +L +N ++ +A LEF + ++ + W Sbjct: 74 YGPLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNR-MASGLEFKSVADSVLFLRDKRW 132 Query: 241 RVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGK 420 R A++ + + + EM+ L +A L L + A G+ +++ + T DV+ Sbjct: 133 EEVRGALMSAFSPEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVAS 192 Query: 421 AVFNYDFDS 447 F DS Sbjct: 193 VPFGTPVDS 201
>CP4A6_RABIT (P14580) Cytochrome P450 4A6 precursor (EC 1.14.15.3) (CYPIVA6)| (Lauric acid omega-hydroxylase) (P450-KA-1) Length = 510 Score = 50.1 bits (118), Expect = 4e-06 Identities = 31/116 (26%), Positives = 57/116 (49%), Gaps = 1/116 (0%) Frame = +1 Query: 91 GPKSFVIVSDPDIAKHIL-RDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVRRRAIVP 267 G ++ +++ DPD K IL R + KA L +G GL+ +G+ W RR + P Sbjct: 92 GSRAHLLIYDPDYMKVILGRSDPKAQGS---YRFLAPWIGYGLLLLNGQTWFQHRRMLTP 148 Query: 268 SLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVFNY 435 + H + +GL + + +K ++ ++ +E+ S +TLD I K F++ Sbjct: 149 AFHYDILKPYVGLMADSVQIMLDKWEQLVSQDSSLEVFQDISLMTLDTIMKCAFSH 204
>CP4V2_PONPY (Q5RCN6) Cytochrome P450 4V2 (EC 1.14.-.-)| Length = 525 Score = 49.7 bits (117), Expect = 6e-06 Identities = 37/147 (25%), Positives = 68/147 (46%), Gaps = 1/147 (0%) Frame = +1 Query: 46 YDHFLTHGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPA 225 Y H L +L +GP V + + + + IL +S+ K + + LE +G GL+ + Sbjct: 80 YTEEYRHMPLLKLWVGPVPMVALYNAENVEVILT-SSRQIDKSSMYKFLEPWLGLGLLTS 138 Query: 226 DGEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTL 405 G WR RR+ + P+ H + + + + + + L +KL+K + E + L Sbjct: 139 TGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHVNQ-EAFNCFFYITLCAL 197 Query: 406 DVIGKAVFNYDFDSLSYDNG-MVEAVY 483 D+I + + + S D+ V AVY Sbjct: 198 DIICETAMGKNIGAQSNDDSEYVRAVY 224
>CP4Z1_HUMAN (Q86W10) Cytochrome P450 4Z1 (EC 1.14.14.1) (CYPIVZ1)| Length = 505 Score = 49.7 bits (117), Expect = 6e-06 Identities = 30/111 (27%), Positives = 53/111 (47%) Frame = +1 Query: 103 FVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVRRRAIVPSLHQK 282 F V DPD AK +L+ + +ILE +G GL+ DG W+ R+ + P + Sbjct: 90 FFSVHDPDYAKILLKRQDP--KSAVSHKILESWVGRGLVTLDGSKWKKHRQIVKPGFNIS 147 Query: 283 FVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVFNY 435 + I + ++ + K ++ A+ +E+ S +TLD I K F++ Sbjct: 148 ILKIFITMMSESVRMMLNKWEEHIAQNSRLELFQHVSLMTLDSIMKCAFSH 198
>C94A1_VICSA (O81117) Cytochrome P450 94A1 (EC 1.14.-.-) (P450-dependent fatty| acid omega-hydroxylase) Length = 514 Score = 49.3 bits (116), Expect = 8e-06 Identities = 37/155 (23%), Positives = 63/155 (40%), Gaps = 7/155 (4%) Frame = +1 Query: 97 KSFVIVSDPDIAKHILRDNSKAYSKG-ILAEILEFVMGTGLIPADGEVWRVRRRAIVPSL 273 K +I +P +HIL++ Y KG L +GTG+ +G W+ +R+ Sbjct: 91 KRQIITGNPSTVQHILKNQFSNYQKGTTFTNTLSDFLGTGIFNTNGPNWKFQRQVASHEF 150 Query: 274 HQKFVTEMIG--LFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVFNYDFDS 447 + K + + + + + RL L + I++ + + R T D I F YD + Sbjct: 151 NTKSIRNFVEHIVDTELTNRLIPILTSSTQTNNILDFQDILQRFTFDNICNIAFGYDPEY 210 Query: 448 LSYDNG---MVEAVYVTLREAEMRSTSPIP-TWKI 540 L+ EA + R P+P WKI Sbjct: 211 LTPSTNRSKFAEAYEDATEISSKRFRLPLPIIWKI 245
>C6A23_DROME (Q9V771) Probable cytochrome P450 6a23 (EC 1.14.-.-) (CYPVIA23)| Length = 502 Score = 49.3 bits (116), Expect = 8e-06 Identities = 35/132 (26%), Positives = 64/132 (48%), Gaps = 4/132 (3%) Frame = +1 Query: 109 IVSDPDIAKHIL-RDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVRRRAIVPSLHQKF 285 +++D ++ K +L +D + ++GI ++ + L +G+ WR R + P+ Sbjct: 82 VITDLELVKRVLIKDFNHFENRGIFYNEIDDPLSATLFSIEGQKWRHLRHKLTPTFTSGK 141 Query: 286 VTEMIGLFGKASGRLCEKLDKA---AAEGEIVEMESLFSRLTLDVIGKAVFNYDFDSLSY 456 + M + K G EK+ A EG+++E+ L +R T DVIG F + +SL Sbjct: 142 MKNMFPIIVKV-GEEMEKIFSAKTTTGEGQVLEIVDLVARYTADVIGNCAFGLNCNSLQN 200 Query: 457 DNGMVEAVYVTL 492 N A +VT+ Sbjct: 201 PN----AEFVTI 208
>CP3AI_RAT (Q64581) Cytochrome P450 3A18 (EC 1.14.14.1) (CYPIIIA18)| (P450(6)beta-2) Length = 497 Score = 49.3 bits (116), Expect = 8e-06 Identities = 33/136 (24%), Positives = 65/136 (47%), Gaps = 1/136 (0%) Frame = +1 Query: 49 DHFLTHGGLFRLNLGPKSFVIVSDPDIAKHIL-RDNSKAYSKGILAEILEFVMGTGLIPA 225 D + +G ++ GP+ F+ + DP+I K +L ++ ++ + F M + + Sbjct: 63 DCYKKYGKIWGFYEGPQPFLAIMDPEIIKMVLVKECYSVFTNRRCFGPMGF-MKKAITMS 121 Query: 226 DGEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTL 405 + E W+ R + P+ + EM L + L + L + A+GE + M+ +F ++ Sbjct: 122 EDEEWKRLRTILSPTFTSGKLKEMFPLMRQYGDTLLKNLRREEAKGEPINMKDIFGAYSM 181 Query: 406 DVIGKAVFNYDFDSLS 453 DVI F + DSL+ Sbjct: 182 DVITGTSFGVNVDSLN 197
>CP4A5_RABIT (P14579) Cytochrome P450 4A5 precursor (EC 1.14.15.3) (CYPIVA5)| (Lauric acid omega-hydroxylase) Length = 511 Score = 48.9 bits (115), Expect = 1e-05 Identities = 33/115 (28%), Positives = 56/115 (48%) Frame = +1 Query: 91 GPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVRRRAIVPS 270 G K V + DPD K IL S S+G + ++ G GL+ +G+ W RR + P+ Sbjct: 92 GNKVRVQLYDPDYMKVIL-GRSDPKSRGSYTFVAPWI-GYGLLLLNGQPWFQHRRMLTPA 149 Query: 271 LHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVFNY 435 H + +GL + + +K ++ ++ +E+ S +TLD I K F+Y Sbjct: 150 FHYDILKPYVGLMVDSVQIMLDKWEQLVSQDSSLEVFQDISLMTLDTIMKCAFSY 204
>CP6B1_PAPPO (Q04552) Cytochrome P450 6B1 (EC 1.14.14.1) (CYPVIB1)| (CYP6B1V1/CYP6B1V2/ CYP6B1V3) Length = 498 Score = 48.1 bits (113), Expect = 2e-05 Identities = 37/160 (23%), Positives = 71/160 (44%), Gaps = 3/160 (1%) Frame = +1 Query: 10 RWRPGXAIFLPLYDHFLTHG--GLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYS-KGIL 180 R +P ++ +YD F G++R+ V++ D DI KH+L + ++++ +G+ Sbjct: 49 RRKPQVMVYKSIYDEFPNEKVVGIYRMTTPS---VLLRDLDIIKHVLIKDFESFADRGV- 104 Query: 181 AEILEFVMGTGLIPADGEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAE 360 E +G + ADG+ WR R P + M+ L + R +D+ + Sbjct: 105 -EFSLDGLGANIFHADGDRWRSLRNRFTPLFTSGKLKSMLPLMSQVGDRFINSIDEVSQT 163 Query: 361 GEIVEMESLFSRLTLDVIGKAVFNYDFDSLSYDNGMVEAV 480 + +L + T+ I VF L+ D GM++ + Sbjct: 164 QPEQSIHNLVQKFTMTNIAACVF-----GLNLDEGMLKTL 198
>CP3AS_BOVIN (P79102) Cytochrome P450 3A28 (EC 1.14.14.1) (CYPIIIA28)| Length = 507 Score = 48.1 bits (113), Expect = 2e-05 Identities = 38/143 (26%), Positives = 65/143 (45%), Gaps = 4/143 (2%) Frame = +1 Query: 37 LPLYDH--FLTHGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILE--FVM 204 +P +D+ F +G ++ G + + ++DPDI K +L + YS I +M Sbjct: 57 IPEFDNQCFKKYGKMWGFYEGRQPMLAITDPDIIKTVLV--KECYSVFTNRRIFGPMGIM 114 Query: 205 GTGLIPADGEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMES 384 + A E W+ R + P+ + EM + G+ L L K A +G V M+ Sbjct: 115 KYAISLAWDEQWKRIRTLLSPAFTSGKLKEMFPIIGQYGDMLVRNLRKEAEKGNPVNMKD 174 Query: 385 LFSRLTLDVIGKAVFNYDFDSLS 453 +F ++DVI F + DSL+ Sbjct: 175 MFGAYSMDVITGTAFGVNIDSLN 197
>CP2B4_RABIT (P00178) Cytochrome P450 2B4 (EC 1.14.14.1) (CYPIIB4) (P450-LM2)| (Isozyme 2) (P450 types B0 and B1) Length = 491 Score = 48.1 bits (113), Expect = 2e-05 Identities = 38/133 (28%), Positives = 69/133 (51%), Gaps = 6/133 (4%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYS-KGILAEILEFVMGTGLIPADGEVW 240 +G +F + LG + V++ D + L D ++A+S +G +A + G G+I A+GE W Sbjct: 62 YGDVFTVYLGSRPVVVLCGTDAIREALVDQAEAFSGRGKIAVVDPIFQGYGVIFANGERW 121 Query: 241 RVRRRAIVPSLH-----QKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTL 405 R RR + ++ ++ V E I + + L E+L K ++G +++ LF +T Sbjct: 122 RALRRFSLATMRDFGMGKRSVEERI---QEEARCLVEELRK--SKGALLDNTLLFHSITS 176 Query: 406 DVIGKAVFNYDFD 444 ++I VF FD Sbjct: 177 NIICSIVFGKRFD 189
>CP4F6_RAT (P51871) Cytochrome P450 4F6 (EC 1.14.14.1) (CYPIVF6)| Length = 537 Score = 47.8 bits (112), Expect = 2e-05 Identities = 24/94 (25%), Positives = 48/94 (51%), Gaps = 1/94 (1%) Frame = +1 Query: 202 MGTGLIPADGEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEI-VEM 378 +G GL+ + GE W RR + P+ H + + +F K+ + K + A+G ++M Sbjct: 132 LGDGLLMSAGEKWNHHRRLLTPAFHFDILKSYVKIFNKSVNTMHAKWQRLTAKGSARLDM 191 Query: 379 ESLFSRLTLDVIGKAVFNYDFDSLSYDNGMVEAV 480 S +TLD + K +F++D + ++ + A+ Sbjct: 192 FEHISLMTLDSLQKCIFSFDSNCQESNSEYIAAI 225
>C4G15_DROME (Q9VYY4) Cytochrome P450 4g15 (EC 1.14.-.-) (CYPIVG15)| Length = 574 Score = 47.8 bits (112), Expect = 2e-05 Identities = 31/137 (22%), Positives = 60/137 (43%), Gaps = 5/137 (3%) Frame = +1 Query: 19 PGXAIFLPLYDHFLTHGGLFRLNLGPKSFVIVSDPD-----IAKHILRDNSKAYSKGILA 183 P ++F + + ++ +GPK V + DP ++ H+ D + Y Sbjct: 64 PASSVFRTVIRKSAPFEHIAKMWIGPKLVVFIYDPRDVELLLSSHVYIDKASEY------ 117 Query: 184 EILEFVMGTGLIPADGEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEG 363 + + +G GL+ + G+ WR R+ I P+ H + I LF + S + KL A +G Sbjct: 118 KFFKPWLGDGLLISTGQKWRSHRKLIAPTFHLNVLKSFIELFNENSRNVVRKL--RAEDG 175 Query: 364 EIVEMESLFSRLTLDVI 414 + S T++++ Sbjct: 176 RTFDCHDYMSEATVEIL 192
>C4AD1_DROME (Q9V4T3) Probable cytochrome P450 4ad1 (EC 1.14.-.-) (CYPIVAD1)| Length = 516 Score = 47.8 bits (112), Expect = 2e-05 Identities = 28/116 (24%), Positives = 57/116 (49%) Frame = +1 Query: 106 VIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVRRRAIVPSLHQKF 285 +++SDP ++IL +S Y K L L +G GL+ + G W ++ P+ + Sbjct: 83 MMLSDPAEIQNILSSSSLLY-KEHLYSFLRPWLGDGLLTSSGARWLKHQKLYAPAFERSA 141 Query: 286 VTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVFNYDFDSLS 453 + + + + G+ +KLD + E+ + + L ++ TLD++ + D SL+ Sbjct: 142 IEGYLRVVHRTGGQFVQKLDVLSDTQEVFDAQELVAKCTLDIVCENATGQDSSSLN 197
>CP6B2_HELAM (Q27664) Cytochrome P450 6B2 (EC 1.14.14.1) (CYPVIB2)| Length = 504 Score = 47.4 bits (111), Expect = 3e-05 Identities = 29/128 (22%), Positives = 56/128 (43%) Frame = +1 Query: 70 GLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVR 249 G++R+ ++V D ++ KHI+ + + +S L E + +G L ADG+ WR Sbjct: 73 GIYRMT---SPCLLVRDLEVIKHIMIKDFEVFSDRGL-EFSKEGLGQNLFHADGDTWRTL 128 Query: 250 RRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVF 429 R P + M L + + + + K + + E+ +L T+ I F Sbjct: 129 RNRFTPIFTSGKLKNMFYLMNEGADNFIDHVSKECEKHQEFEIHTLLQTYTMSTISSCAF 188 Query: 430 NYDFDSLS 453 +D++S Sbjct: 189 GVSYDTIS 196
>CP2G1_RABIT (P24461) Cytochrome P450 2G1 (EC 1.14.14.1) (CYPIIG1) (P450-NMB)| (Olfactive) Length = 494 Score = 47.4 bits (111), Expect = 3e-05 Identities = 41/159 (25%), Positives = 75/159 (47%), Gaps = 6/159 (3%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYS-KGILAEILEFVMGTGLIPADGEVW 240 +G +F + +GP+ VI+ + K L D + +S +G LA + G G+ A+GE W Sbjct: 65 YGPVFTVYMGPRPVVILCGHEAVKEALVDRADEFSGRGELASVERNFQGHGVALANGERW 124 Query: 241 RVRRRAIVPSLH-----QKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTL 405 R+ RR + L ++ + E I + +G L E+ K +G ++ SR Sbjct: 125 RILRRFSLTILRDFGMGKRSIEERI---QEEAGYLLEEFRK--TKGAPIDPTFFLSRTVS 179 Query: 406 DVIGKAVFNYDFDSLSYDNGMVEAVYVTLREAEMRSTSP 522 +VI VF FD Y++ ++ + E+ + ++P Sbjct: 180 NVISSVVFGSRFD---YEDKQFLSLLRMINESFIEMSTP 215
>CP4D2_DROME (Q27589) Cytochrome P450 4d2 (EC 1.14.-.-) (CYPIVD2)| Length = 501 Score = 47.4 bits (111), Expect = 3e-05 Identities = 29/119 (24%), Positives = 59/119 (49%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWR 243 +G L+R+ + + V +DP + +L + + +K L ++L +G GL+ + G W Sbjct: 65 YGRLYRVWILHQLAVFSTDPRDIEFVL-SSQQHITKNNLYKLLNCWLGDGLLMSTGRKWH 123 Query: 244 VRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGK 420 RR+ I P+ H K + + + +F + S + E+L A + + + LD+I + Sbjct: 124 GRRKIITPTFHFKILEQFVEIFDQQSAVMVEQLQSRADGKTPINIFPVICLTALDIIAE 182
>CP4V3_MOUSE (Q9DBW0) Cytochrome P450 4V3 (EC 1.14.-.-)| Length = 525 Score = 47.4 bits (111), Expect = 3e-05 Identities = 40/160 (25%), Positives = 69/160 (43%), Gaps = 4/160 (2%) Frame = +1 Query: 16 RPGXAIF---LPLYDHFLTHGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAE 186 +P A F L Y H + +L +GP V + + + IL +SK K L + Sbjct: 67 KPNNAEFFQQLIYYTEEFRHLPIIKLWIGPVPLVALYKAENVEVILT-SSKQIDKSFLYK 125 Query: 187 ILEFVMGTGLIPADGEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGE 366 L+ +G GL+ + G WR RR+ + P+ H + + + + + L KL+K + E Sbjct: 126 FLQPWLGLGLLTSTGSKWRTRRKMLTPTFHFTILENFLDVMNEQANILVNKLEKHVNQ-E 184 Query: 367 IVEMESLFSRLTLDVIGKAVFNYDFDSLS-YDNGMVEAVY 483 + LD+I + + + S D+ V VY Sbjct: 185 AFNCFFYITLCALDIICETAMGKNIGAQSNNDSEYVRTVY 224
>CP4P3_DROME (Q9V559) Probable cytochrome P450 4p3 (EC 1.14.-.-) (CYPIVP3)| Length = 515 Score = 47.0 bits (110), Expect = 4e-05 Identities = 32/147 (21%), Positives = 63/147 (42%) Frame = +1 Query: 112 VSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVRRRAIVPSLHQKFVT 291 V D D A+ +L D + +KG + + L + TGL+ + G+ W RR+ + P+ H + Sbjct: 96 VIDADSAERVLNDPN-LINKGTIYDFLHPFLRTGLLTSTGKKWHARRKMLSPTFHFNILN 154 Query: 292 EMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVFNYDFDSLSYDNGMV 471 + +F S + E+ + I+ + + R TL+ I + D ++ Sbjct: 155 QFQEIFITESLKFLEQF--KGNDEAIISLNEVIPRFTLNSICETAMGVKLDEMAEKGDRY 212 Query: 472 EAVYVTLREAEMRSTSPIPTWKIPIWK 552 + + E +R S W ++K Sbjct: 213 RENFRQIEECFIRRMSNPLLWSDTLFK 239
>CP3AC_CANFA (P24463) Cytochrome P450 3A12 (EC 1.14.14.1) (CYPIIIA12)| (P450-PBD-1) Length = 503 Score = 46.6 bits (109), Expect = 5e-05 Identities = 33/136 (24%), Positives = 64/136 (47%), Gaps = 2/136 (1%) Frame = +1 Query: 55 FLTHGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFV--MGTGLIPAD 228 F +G ++ G + + ++DPD+ K +L + YS L V M + + ++ Sbjct: 65 FSKYGRMWGFYDGRQPVLAITDPDMIKTVLV--KECYSVFTNRRTLGPVGFMKSAISLSE 122 Query: 229 GEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLD 408 E W+ R + P+ + EM + G+ L L K A +G+ + ++ +F ++D Sbjct: 123 DEEWKRMRTLLSPTFTTGKLKEMFPIIGQYGDVLVNNLRKEAEKGKAINLKDVFGAYSMD 182 Query: 409 VIGKAVFNYDFDSLSY 456 VI F + DSL++ Sbjct: 183 VITSTSFGVNIDSLNH 198
>CP6B7_HELAM (O61387) Cytochrome P450 6B7 (EC 1.14.14.1) (CYPVIB7)| Length = 504 Score = 46.6 bits (109), Expect = 5e-05 Identities = 29/117 (24%), Positives = 52/117 (44%), Gaps = 1/117 (0%) Frame = +1 Query: 106 VIVSDPDIAKHILRDNSKAY-SKGILAEILEFVMGTGLIPADGEVWRVRRRAIVPSLHQK 282 ++V D + KHI+ + +A+ +G+ E + +G L ADGE WR R P Sbjct: 82 LLVRDFHVIKHIMIKDFEAFRDRGV--EFSKEGLGQNLFHADGETWRALRNRFTPIFTSG 139 Query: 283 FVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVFNYDFDSLS 453 + M L + + + + K + + E+ SL T+ I F ++S+S Sbjct: 140 KLKNMFYLMHEGADNFIDHVSKECEKKQEFEVHSLLQTYTMSTISSCAFGVSYNSIS 196
>CP6B6_HELAM (Q95031) Cytochrome P450 6B6 (EC 1.14.14.1) (CYPVIB6)| Length = 504 Score = 46.6 bits (109), Expect = 5e-05 Identities = 30/128 (23%), Positives = 56/128 (43%), Gaps = 1/128 (0%) Frame = +1 Query: 70 GLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYS-KGILAEILEFVMGTGLIPADGEVWRV 246 G++R+ ++V D ++ KHI+ + + +S +G+ E + +G+ L ADGE WR Sbjct: 73 GIYRMT---SPCLLVRDLEVIKHIMIKDFEVFSDRGV--EFSKEGLGSNLFHADGETWRA 127 Query: 247 RRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAV 426 R P M L + + + + + + E+ SL T+ I Sbjct: 128 LRNRFTPIFTSGKPKNMFYLMHEGADNFIDHVSAECEKNQEFEVHSLLQTYTMSTIAACA 187 Query: 427 FNYDFDSL 450 F +DS+ Sbjct: 188 FGISYDSI 195
>C356_FUNHE (Q8AXY5) Cytochrome P450 3A56 (EC 1.14.14.1) (CYPIIIA56)| Length = 496 Score = 46.6 bits (109), Expect = 5e-05 Identities = 30/130 (23%), Positives = 59/130 (45%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWR 243 +G ++ + G + + V+DP+I K +L ++ L + L A+ + W+ Sbjct: 67 YGKVWGIYDGRQPVLCVTDPEIIKAVLVKECLSFFTNRRNFHLNGPLYDALSVAEDDQWK 126 Query: 244 VRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKA 423 R + PS + EM + S L + K A + E ++++ F ++DV+ Sbjct: 127 RIRSVLSPSFTSGRLKEMFEIMKNHSANLIRSMKKKADKDEPLDLKEFFGSYSMDVVTST 186 Query: 424 VFNYDFDSLS 453 F+ D DSL+ Sbjct: 187 AFSVDIDSLN 196
>C4AC1_DROME (Q9VMS9) Probable cytochrome P450 4ac1 (EC 1.14.-.-) (CYPIVAC1)| Length = 509 Score = 46.2 bits (108), Expect = 6e-05 Identities = 29/135 (21%), Positives = 64/135 (47%) Frame = +1 Query: 121 PDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVRRRAIVPSLHQKFVTEMI 300 P+ A+ + + ++K +K ++ E++ +G GL+ + W RR+A+ P+ H + + Sbjct: 101 PEEAEEVFQ-STKLITKNVVYELIRPFLGDGLLISTDHKWHSRRKALTPAFHFNVLQSFL 159 Query: 301 GLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVFNYDFDSLSYDNGMVEAV 480 G+F + + L+K + E+ E+ + TL+ I + D +S N +A+ Sbjct: 160 GIFKEECKKFLNVLEK-NLDAEL-ELNQVIPPFTLNNICETALGVKLDDMSEGNEYRKAI 217 Query: 481 YVTLREAEMRSTSPI 525 + R +P+ Sbjct: 218 HAIEEVLIQRVCNPL 232
>CP4AE_MOUSE (O35728) Cytochrome P450 4A14 precursor (EC 1.14.15.3) (CYPIVA14)| (Lauric acid omega-hydroxylase 3) (P450-LA-omega 3) Length = 507 Score = 46.2 bits (108), Expect = 6e-05 Identities = 30/111 (27%), Positives = 54/111 (48%), Gaps = 1/111 (0%) Frame = +1 Query: 106 VIVSDPDIAKHIL-RDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVRRRAIVPSLHQK 282 V++ DPD K +L R + KA GI ++ G GL+ +G+ W RR + P+ H Sbjct: 94 VLLYDPDYVKVVLGRSDPKA--SGIYQFFAPWI-GYGLLLLNGKKWFQHRRMLTPAFHYD 150 Query: 283 FVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVFNY 435 + + + + + +K +K + +E+ S +TLD + K F+Y Sbjct: 151 ILKPYVKIMADSVNIMLDKWEKLDGQDHPLEIFHCVSLMTLDTVMKCAFSY 201
>CP2BB_CANFA (P24460) Cytochrome P450 2B11 (EC 1.14.14.1) (CYPIIB11) (P450| PBD-2) Length = 494 Score = 46.2 bits (108), Expect = 6e-05 Identities = 37/132 (28%), Positives = 67/132 (50%), Gaps = 6/132 (4%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYS-KGILAEILEFVMGTGLIPADGEVW 240 +G +F + LGP+ V++ D + L DN++A+S +G +A + G G++ A+GE W Sbjct: 62 YGDVFTVYLGPRRTVMLCGIDAIREALVDNAEAFSGRGKIAVVEPVFQGYGVVFANGERW 121 Query: 241 RVRRRAIVPSLH-----QKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTL 405 + RR + ++ ++ V E I + + L E+L K EG + + F +T Sbjct: 122 KTLRRFSLATMRDFGMGKRSVEERI---QEEAQCLVEELRK--TEGVLQDPTFFFHSMTA 176 Query: 406 DVIGKAVFNYDF 441 ++I VF F Sbjct: 177 NIICSIVFGKRF 188
>CP4AB_HUMAN (Q02928) Cytochrome P450 4A11 precursor (EC 1.14.15.3) (CYPIVA11)| (Fatty acid omega-hydroxylase) (P-450 HK omega) (Lauric acid omega-hydroxylase) (CYP4AII) (P450-HL-omega) Length = 519 Score = 46.2 bits (108), Expect = 6e-05 Identities = 32/116 (27%), Positives = 55/116 (47%), Gaps = 1/116 (0%) Frame = +1 Query: 91 GPKSFVIVSDPDIAKHIL-RDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVRRRAIVP 267 G K V + DPD K IL R + K++ L +G GL+ +G+ W RR + P Sbjct: 92 GGKVRVQLYDPDYMKVILGRSDPKSHGS---YRFLAPWIGYGLLLLNGQTWFQHRRMLTP 148 Query: 268 SLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVFNY 435 + H + +GL + + +K ++ + +E+ S +TLD I K F++ Sbjct: 149 AFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSH 204
>CP2B5_RABIT (P12789) Cytochrome P450 2B5 (EC 1.14.14.1) (CYPIIB5) (P450 type| B2) (P450 form HP1) Length = 491 Score = 46.2 bits (108), Expect = 6e-05 Identities = 37/133 (27%), Positives = 68/133 (51%), Gaps = 6/133 (4%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYS-KGILAEILEFVMGTGLIPADGEVW 240 +G +F + LG + V++ D + L D ++A+S +G +A + G G+ A+GE W Sbjct: 62 YGDVFTVYLGSRPVVVLCGTDAIREALVDQAEAFSGRGKIAVVDPIFQGYGVFFANGEHW 121 Query: 241 RVRRRAIVPSLH-----QKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTL 405 R RR + ++ ++ V E I + + L E+L K ++G +++ LF +T Sbjct: 122 RALRRFSLATMRDFGMGKRSVEERI---QEEARCLVEELRK--SKGALLDNTLLFHSVTS 176 Query: 406 DVIGKAVFNYDFD 444 ++I VF FD Sbjct: 177 NIICSIVFGKRFD 189
>C4AC3_DROME (Q9VMS7) Probable cytochrome P450 4ac3 (EC 1.14.-.-) (CYPIVAC3)| Length = 509 Score = 45.8 bits (107), Expect = 8e-05 Identities = 25/111 (22%), Positives = 54/111 (48%) Frame = +1 Query: 151 NSKAYSKGILAEILEFVMGTGLIPADGEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRL 330 ++K +K + E++ +G GL+ + + W RR+ + P+ H + + +F + S + Sbjct: 110 STKITTKNMSYELIRPFLGDGLLISIDQKWHTRRKTLTPAFHFNILQSFLSIFKEESKKF 169 Query: 331 CEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVFNYDFDSLSYDNGMVEAVY 483 + LDK G +E+ + + TL+ I + D +S N +A++ Sbjct: 170 IKILDKNV--GFELELNQIIPQFTLNNICETALGVKLDDMSEGNEYRKAIH 218
>C4D20_DROME (Q9W011) Probable cytochrome P450 4d20 (EC 1.14.-.-) (CYPIVD20)| Length = 510 Score = 45.4 bits (106), Expect = 1e-04 Identities = 36/151 (23%), Positives = 61/151 (40%), Gaps = 5/151 (3%) Frame = +1 Query: 49 DHFLTHGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPAD 228 + F +G FR + +S + D + IL ++ KG L E L + GL+ + Sbjct: 62 EKFDKYGKTFRFWILGESLIYTKDLQYFETIL-SSTTLLEKGQLYEYLRPFLNDGLLVST 120 Query: 229 GEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLD 408 G W RR+ + H K + + + + S + + L K A V+M S LD Sbjct: 121 GRKWHARRKIFTHAFHFKVLEHYVEIMDRHSSVMVDNLRKVADGKTAVDMLKYVSLAALD 180 Query: 409 VIGKAVFNYDFDS-----LSYDNGMVEAVYV 486 VI +A ++ Y + VY+ Sbjct: 181 VITEAAMGVQVNAQNDPDFPYIKALKSVVYI 211
>CP4X1_RAT (Q8K4D6) Cytochrome P450 4X1 (EC 1.14.14.1) (CYPIVX1)| Length = 507 Score = 45.4 bits (106), Expect = 1e-04 Identities = 31/120 (25%), Positives = 57/120 (47%), Gaps = 3/120 (2%) Frame = +1 Query: 88 LGP-KSFVIVSDPDIAKHIL-RDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVRRRAI 261 +GP ++F + DPD AK L R + K L +++ +G GL+ DG W R + Sbjct: 84 VGPFQAFFYIYDPDYAKIFLSRTDPKTQ---YLHQLMTPFLGRGLLNLDGPRWFQHRCLL 140 Query: 262 VPSLHQKFVTEMIGLFGKASGRLCEKLDKA-AAEGEIVEMESLFSRLTLDVIGKAVFNYD 438 P+ HQ + + + + + +K +K + +E+ + +TLD+I K F + Sbjct: 141 TPAFHQDILKPCVDMMAHSVNMMLDKWEKTWTTQETTIEVFEHINLMTLDIIMKCAFGQE 200
>CP3AR_ONCMY (O42563) Cytochrome P450 3A27 (EC 1.14.14.1) (CYPIIIA27)| Length = 518 Score = 45.4 bits (106), Expect = 1e-04 Identities = 22/77 (28%), Positives = 39/77 (50%) Frame = +1 Query: 223 ADGEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLT 402 A+ + WR R + PS + EM G+ + S L + K A + + +E++ F + Sbjct: 122 AEDDTWRRIRSVLSPSFTSGRLKEMFGIMKQHSSTLLSGMKKQADKDQTIEVKEFFGPYS 181 Query: 403 LDVIGKAVFNYDFDSLS 453 +DV+ F+ D DSL+ Sbjct: 182 MDVVTSTAFSVDIDSLN 198
>C330_FUNHE (Q9PVE8) Cytochrome P450 3A30 (EC 1.14.14.1) (CYPIIIA30)| Length = 496 Score = 45.1 bits (105), Expect = 1e-04 Identities = 29/130 (22%), Positives = 59/130 (45%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWR 243 +G ++ + G + + V+DP+I K +L ++ L + + A+ + W+ Sbjct: 67 YGKVWGIYDGRQPVLCVTDPEIIKAVLVKECLSFFTNRRNFRLNGPLYDAVSIAEDDQWK 126 Query: 244 VRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKA 423 R + PS + EM + S L + K A + E ++++ F ++DV+ Sbjct: 127 RIRSVLSPSFTSGRLKEMFEIMKNHSANLIRSMKKKADKDEPLDLKEFFGSYSMDVVTST 186 Query: 424 VFNYDFDSLS 453 F+ D DSL+ Sbjct: 187 AFSVDIDSLN 196
>CP133_DROME (Q9VGB3) Probable cytochrome P450 313a3 (EC 1.14.-.-)| (CYPCCCXIIIA3) Length = 492 Score = 45.1 bits (105), Expect = 1e-04 Identities = 25/93 (26%), Positives = 40/93 (43%) Frame = +1 Query: 88 LGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVRRRAIVP 267 +GP FVI DP IA+ I I ++ + G GL+ + W RR+ + P Sbjct: 73 VGPTPFVITRDPKIAEEIFLSPECLNRSSIFSKPVNSCTGDGLLSLEASKWVDRRKNLNP 132 Query: 268 SLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGE 366 + Q + + +F + L LD +GE Sbjct: 133 AFKQNVLLSFLPIFNSEAKTLVAFLDSLVGQGE 165
>CP46A_HUMAN (Q9Y6A2) Cytochrome p450 46A1 (EC 1.14.13.98) (Cholesterol| 24-hydroxylase) (CH24H) Length = 500 Score = 45.1 bits (105), Expect = 1e-04 Identities = 34/135 (25%), Positives = 64/135 (47%), Gaps = 6/135 (4%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHIL-----RDNSKAYSKGILAEILEFVMGTGLI-PA 225 +G + R+N+ K+ VIV+ P+ K L +SK Y + + E + G GL+ Sbjct: 71 YGPVVRVNVFHKTSVIVTSPESVKKFLMSTKYNKDSKMY-RALQTVFGERLFGQGLVSEC 129 Query: 226 DGEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTL 405 + E W +RR I + + + ++ F + + +L E L+ A V M+ + + + Sbjct: 130 NYERWHKQRRVIDLAFSRSSLVSLMETFNEKAEQLVEILEAKADGQTPVSMQDMLTYTAM 189 Query: 406 DVIGKAVFNYDFDSL 450 D++ KA F + L Sbjct: 190 DILAKAAFGMETSML 204
>STCS_EMENI (Q00714) Probable sterigmatocystin biosynthesis P450 monooxygenase| stcS (EC 1.14.-.-) (Cytochrome P450 59) Length = 505 Score = 45.1 bits (105), Expect = 1e-04 Identities = 38/132 (28%), Positives = 59/132 (44%), Gaps = 3/132 (2%) Frame = +1 Query: 28 AIFLPLYDHFLTHGGLFRLNLGPKS--FVIVSDPDIAKHILRDNSKAYSKGILAEILEFV 201 +I L L F G+F +N+ P S +++V+ P A I N IL LE + Sbjct: 29 SIMLKLSQKF--RSGMFYINMWPFSGTWLVVATPSGAAQIQSLNLS--KPNILRRPLETI 84 Query: 202 MG-TGLIPADGEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEM 378 G L+ GE W+ R P + ++ + L CE+L + A G + ++ Sbjct: 85 TGGPSLMSMHGETWKRWRALFNPGFNPNYLIGLAPLIADEVVVFCEQLRQKARTGTVFQL 144 Query: 379 ESLFSRLTLDVI 414 E L RLT+D I Sbjct: 145 EPLTLRLTVDTI 156
>CP343_HUMAN (Q9HB55) Cytochrome P450 3A43 (EC 1.14.14.1)| Length = 503 Score = 45.1 bits (105), Expect = 1e-04 Identities = 29/131 (22%), Positives = 62/131 (47%), Gaps = 1/131 (0%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHIL-RDNSKAYSKGILAEILEFVMGTGLIPADGEVW 240 +G ++ L G + +++ DPD+ K +L ++ ++ + + F+ + L A+ E W Sbjct: 68 YGEMWGLYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLK-SALSFAEDEEW 126 Query: 241 RVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGK 420 + R + P+ EM+ + + L L + A + + ++ F T+DVI Sbjct: 127 KRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITG 186 Query: 421 AVFNYDFDSLS 453 +F + DSL+ Sbjct: 187 TLFGVNLDSLN 197
>CP2F2_RAT (O35293) Cytochrome P450 2F2 (EC 1.14.14.-) (CYPIIF2) (Naphthalene| dehydrogenase) (Naphthalene hydroxylase) (P450-NAH-2) Length = 491 Score = 45.1 bits (105), Expect = 1e-04 Identities = 32/137 (23%), Positives = 60/137 (43%), Gaps = 10/137 (7%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYS-KGILAEILEFVMGTGLIPADGEVW 240 +G +F + LGP+ +++S K L D + +S +G F G G+ +DGE W Sbjct: 62 YGSVFTVYLGPRRVIVLSGYQTVKEALVDKGEEFSGRGSYPIFFNFTKGNGIAFSDGERW 121 Query: 241 RVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAA---------EGEIVEMESLFS 393 ++ RR F +++ FG + E++ + + EG+ + + S Sbjct: 122 KILRR---------FSVQILRNFGMGKRSIEERILEEGSFLLDVLRKTEGKPFDPVFILS 172 Query: 394 RLTLDVIGKAVFNYDFD 444 R ++I +F FD Sbjct: 173 RSVSNIICSVIFGSRFD 189
>CP3AT_PIG (P79401) Cytochrome P450 3A29 (EC 1.14.14.1) (CYPIIIA29)| Length = 503 Score = 44.7 bits (104), Expect = 2e-04 Identities = 35/137 (25%), Positives = 61/137 (44%), Gaps = 4/137 (2%) Frame = +1 Query: 55 FLTHGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEF----VMGTGLIP 222 F +G ++ + G + + V+DP++ K +L + YS + F M L Sbjct: 65 FQQYGKMWGVYDGRQPLLAVTDPNMIKSVLV--KECYS--VFTNRRSFGPLGAMRNALSL 120 Query: 223 ADGEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLT 402 A+ E W+ R + P+ + EM + L L K A +G+ V M+ +F + Sbjct: 121 AEDEEWKRIRTLLSPTFTSGKLKEMFPIISHYGDLLVSNLRKEAEKGKPVTMKDIFGAYS 180 Query: 403 LDVIGKAVFNYDFDSLS 453 +DVI F + DSL+ Sbjct: 181 MDVITSTAFGVNIDSLN 197
>CP52I_CANMA (Q12586) Cytochrome P450 52A9 (EC 1.14.14.-) (CYPLIIA9)| (Alkane-inducible P450-ALK5-A) Length = 521 Score = 44.7 bits (104), Expect = 2e-04 Identities = 35/137 (25%), Positives = 63/137 (45%), Gaps = 7/137 (5%) Frame = +1 Query: 70 GLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVR 249 G + L K ++ DP+ K IL + +S G + + ++G G+ DGE W+ Sbjct: 87 GTYLFKLFTKDVLVTKDPENIKAILATQFEDFSLGKRLDFFKPLLGYGIFTLDGEGWKHS 146 Query: 250 RRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDK--AAAEGEIVEMESLFSRLTLD----- 408 R + P +F E +G K + L K +G+ +++ LF R T+D Sbjct: 147 RAMLRP----QFAREQVG-HVKLIEPHFQSLKKHIIKNKGQFFDIQELFFRFTVDSATEF 201 Query: 409 VIGKAVFNYDFDSLSYD 459 + G++V + +S+ YD Sbjct: 202 LFGESVESLKDESIGYD 218
>CP4AC_MOUSE (Q91WL5) Cytochrome P450 4A12 (EC 1.14.14.1) (CYPIVA12)| Length = 508 Score = 44.7 bits (104), Expect = 2e-04 Identities = 31/117 (26%), Positives = 53/117 (45%), Gaps = 1/117 (0%) Frame = +1 Query: 91 GPKSFVIVSDPDIAKHIL-RDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVRRRAIVP 267 G K + V DPD K IL R + KA L +G GL+ DG+ W RR + P Sbjct: 90 GSKVRIQVYDPDYMKLILGRSDPKANGS---YRFLAPWIGRGLLLLDGQTWFQHRRMLTP 146 Query: 268 SLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVFNYD 438 + H + + + + +K ++ + +E+ + +TLD I K F+++ Sbjct: 147 AFHYDILKPYTEIMADSVRVMLDKWEQIVGQDSTLEIFRHITLMTLDTIMKCAFSHE 203
>CP4D8_DROME (Q9VS79) Cytochrome P450 4d8 (EC 1.14.-.-) (CYPIVD8)| Length = 463 Score = 44.7 bits (104), Expect = 2e-04 Identities = 28/124 (22%), Positives = 61/124 (49%) Frame = +1 Query: 49 DHFLTHGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPAD 228 ++ L G L R+ + + ++ D ++ + +L + + K + ++L +G GL+ +D Sbjct: 18 EYVLKFGHLQRVWIFNRLLIMSGDAELNEQLL-SSQEHLVKHPVYKVLGQWLGNGLLLSD 76 Query: 229 GEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLD 408 G+VW RR+ I P+ H + + + +F + S +C + A G ++ LD Sbjct: 77 GKVWHQRRKIITPTFHFSILEQFVEVFDQQS-NICVQRLAQKANGNTFDVYRSICAAALD 135 Query: 409 VIGK 420 +I + Sbjct: 136 IIAE 139
>C86A2_ARATH (O23066) Cytochrome P450 86A2 (EC 1.14.-.-)| Length = 553 Score = 44.3 bits (103), Expect = 2e-04 Identities = 35/153 (22%), Positives = 63/153 (41%), Gaps = 6/153 (3%) Frame = +1 Query: 109 IVSDPDIAKHILRDNSKAYSKGILAE-ILEFVMGTGLIPADGEVWRVRRRAIVPSLHQKF 285 + DP +H+L+ Y KG + + +G G+ +DG+ W +R+ + Sbjct: 83 VTCDPKNIEHMLKTRFDNYPKGPTWQAVFHDFLGQGIFNSDGDTWLFQRKTAALEFTTRT 142 Query: 286 VTEMIGLFGKASGRL--CEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVFNYDFDSLS-- 453 + + +G + +L C L+ A E V+++ L RLT D I F D + + Sbjct: 143 LRQAMGRWVNRGIKLRFCPILETAQNNYEPVDLQDLILRLTFDNICGLAFGKDTRTCAPG 202 Query: 454 -YDNGMVEAVYVTLREAEMRSTSPIPTWKIPIW 549 +NG A + R P W++ W Sbjct: 203 LPENGFASAFDRATEASLQRFILPEFLWRLKKW 235
>CP3AE_CAVPO (Q64417) Cytochrome P450 3A14 (EC 1.14.14.1) (CYPIIIA14)| Length = 503 Score = 44.3 bits (103), Expect = 2e-04 Identities = 27/130 (20%), Positives = 62/130 (47%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWR 243 +G ++ L GP+ + +++PD+ K +L + + + M + ++ E W+ Sbjct: 68 YGNMWGLYDGPQPVLAITEPDMIKAVLVKECYSVFTNRRSLVPVGFMKKAVSLSEDEEWK 127 Query: 244 VRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKA 423 R + P+ + EM + + L + L + A +G+ V+++ +F ++D+I Sbjct: 128 RIRTQLSPNFTSGKLKEMFPIIKQYGDVLVKNLRQEAEKGKPVQLKEIFGAYSMDIIVAT 187 Query: 424 VFNYDFDSLS 453 F + DSL+ Sbjct: 188 AFGVNVDSLN 197
>CP2F1_HUMAN (P24903) Cytochrome P450 2F1 (EC 1.14.14.1) (CYPIIF1)| Length = 491 Score = 43.9 bits (102), Expect = 3e-04 Identities = 32/137 (23%), Positives = 59/137 (43%), Gaps = 10/137 (7%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYS-KGILAEILEFVMGTGLIPADGEVW 240 +G ++ ++LGP+ V++S K L D + +S +G F G G+ + G+ W Sbjct: 62 YGSMYTVHLGPRRVVVLSGYQAVKEALVDQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRW 121 Query: 241 RVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKL---------DKAAAEGEIVEMESLFS 393 +V R +F +++ FG + E++ D EGE + + S Sbjct: 122 KVLR---------QFSIQILRNFGMGKRSIEERILEEGSFLLADVRKTEGEPFDPTFVLS 172 Query: 394 RLTLDVIGKAVFNYDFD 444 R ++I +F FD Sbjct: 173 RSVSNIICSVLFGSRFD 189
>THAS_PIG (P47787) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| Length = 534 Score = 43.9 bits (102), Expect = 3e-04 Identities = 25/128 (19%), Positives = 55/128 (42%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWR 243 +G L LG + V++SDPD+ K +L + ++ + + + ++ + W Sbjct: 74 YGPLSGYYLGRRMIVVISDPDMIKQVLAEKFSNFTNRMATGLESKPVADSILFLRDKRWE 133 Query: 244 VRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKA 423 R + + K + ++ L +A L L++ A G+ +++ + T DV+ Sbjct: 134 EVRSVLTSAFSPKKLNKLTPLISQACDLLLAHLERYAESGDAFDIQRCYCCYTTDVVASV 193 Query: 424 VFNYDFDS 447 F +S Sbjct: 194 AFGTQVNS 201
>CP4F3_HUMAN (Q08477) Cytochrome P450 4F3 (EC 1.14.13.30) (CYPIVF3)| (Leukotriene-B(4) omega-hydroxylase) (Leukotriene-B(4) 20-monooxygenase) (Cytochrome P450-LTB-omega) Length = 520 Score = 43.9 bits (102), Expect = 3e-04 Identities = 24/80 (30%), Positives = 42/80 (52%), Gaps = 1/80 (1%) Frame = +1 Query: 202 MGTGLIPADGEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEI-VEM 378 +G GL+ + GE W RR + P+ H + + +F ++ + K A+EG ++M Sbjct: 132 LGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDM 191 Query: 379 ESLFSRLTLDVIGKAVFNYD 438 S +TLD + K VF++D Sbjct: 192 FEHISLMTLDSLQKCVFSFD 211
>CP132_DROME (Q9VGB4) Probable cytochrome P450 313a2 (EC 1.14.-.-)| (CYPCCCXIIIA2) Length = 493 Score = 43.9 bits (102), Expect = 3e-04 Identities = 25/101 (24%), Positives = 38/101 (37%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWR 243 HG + +G VI DP IA+ +L L MG GL+ G W Sbjct: 65 HGSTYMAWIGTTPIVITRDPKIAEKVLTSPFCINRSSQTTNALALSMGYGLLTLQGSKWM 124 Query: 244 VRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGE 366 RR+ + P+ + + +F + L D +GE Sbjct: 125 ARRKHMNPAFKHSVLLSFLPIFNAETDLLVSVFDSFVGQGE 165
>CP6A1_MUSDO (P13527) Cytochrome P450 6A1 (EC 1.14.14.1) (CYPVIA1)| Length = 509 Score = 43.9 bits (102), Expect = 3e-04 Identities = 30/122 (24%), Positives = 54/122 (44%), Gaps = 1/122 (0%) Frame = +1 Query: 88 LGPKSFVIVSDPDIAKHIL-RDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVRRRAIV 264 LG K +V D ++ K +L +D S ++G+ + + L+ +GE WR R + Sbjct: 77 LGHKPAAVVLDKELRKRVLIKDFSNFANRGLYYNEKDDPLTGHLVMVEGEKWRSLRTKLS 136 Query: 265 PSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVFNYDFD 444 P+ + M + RL E + + ++M + +R DVIG F + + Sbjct: 137 PTFTAGKMKYMYNTVLEVGQRLLEVMYEKLEVSSELDMRDILARFNTDVIGSVAFGIECN 196 Query: 445 SL 450 SL Sbjct: 197 SL 198
>CP4AC_RAT (P24464) Cytochrome P450 4A12 (EC 1.14.14.1) (CYPIVA12) (CYPIVA8)| (P450-KP1) (P450-PP1) Length = 508 Score = 43.5 bits (101), Expect = 4e-04 Identities = 29/111 (26%), Positives = 51/111 (45%), Gaps = 2/111 (1%) Frame = +1 Query: 112 VSDPDIAKHIL--RDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVRRRAIVPSLHQKF 285 V DPD K IL D +S LA + G GL+ +G+ W RR + P+ H Sbjct: 97 VYDPDYMKLILGRSDPKSHHSYRFLAPWI----GYGLLLLNGQTWFQHRRMLTPAFHYDT 152 Query: 286 VTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVFNYD 438 + +G+ + + +K ++ + +E+ + +TLD I K F+ + Sbjct: 153 LKPYVGIMADSVRIMLDKWEQIVGQDSTLEIFQHITLMTLDTIMKCAFSQE 203
>CP2G1_RAT (P10610) Cytochrome P450 2G1 (EC 1.14.14.1) (CYPIIG1) (P450-OLF1)| (Olfactive) Length = 494 Score = 43.5 bits (101), Expect = 4e-04 Identities = 39/159 (24%), Positives = 74/159 (46%), Gaps = 6/159 (3%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYS-KGILAEILEFVMGTGLIPADGEVW 240 +G +F + GP+ VI+ + K L D + +S +G + + + G GL ++GE W Sbjct: 65 YGSVFTVYFGPRPVVILCGHEAVKEALVDQADDFSGRGEMPTLEKNFQGYGLALSNGERW 124 Query: 241 RVRRRAIVPSLH-----QKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTL 405 ++ RR + L ++ + E I + +G L E+L K +G ++ SR Sbjct: 125 KILRRFSLTVLRNFGMGKRSIEERI---QEEAGYLLEELHK--VKGAPIDPTFYLSRTVS 179 Query: 406 DVIGKAVFNYDFDSLSYDNGMVEAVYVTLREAEMRSTSP 522 +VI VF FD Y++ ++ + E+ + + P Sbjct: 180 NVICSVVFGKRFD---YEDQRFRSLMKMINESFVEMSMP 215
>C13A4_CAEEL (Q27513) Putative cytochrome P450 CYP13A4 (EC 1.14.-.-)| Length = 520 Score = 43.5 bits (101), Expect = 4e-04 Identities = 31/142 (21%), Positives = 62/142 (43%), Gaps = 3/142 (2%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILR---DNSKAYSKGILAEILEFVMGTGLIPADGE 234 +G ++ + G + ++VS+P+ + DN + L+ A G Sbjct: 64 YGSIYGITEGVEKTLVVSNPEFVHEVFVKQFDNFYGRKTNPIQGDPNKNKRAHLVLAQGH 123 Query: 235 VWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVI 414 W+ R P+ K + +++ + L LD+A+A+G+ V++ + TLD+I Sbjct: 124 RWKRLRTLASPTFSNKSLRKIMSTVEETVVELMRHLDEASAKGKAVDLLDYYQEFTLDII 183 Query: 415 GKAVFNYDFDSLSYDNGMVEAV 480 G+ +SL + N M+ V Sbjct: 184 GRIAMG-QTESLMFRNPMLPKV 204
>CP2B9_MOUSE (P12790) Cytochrome P450 2B9 (EC 1.14.14.1) (CYPIIB9) (Testosterone| 16-alpha hydroxylase) (P450-16-alpha) (Clone PF26) Length = 491 Score = 43.5 bits (101), Expect = 4e-04 Identities = 35/133 (26%), Positives = 66/133 (49%), Gaps = 6/133 (4%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYS-KGILAEILEFVMGTGLIPADGEVW 240 HG +F ++LGP+ V++ + L D+++A+S +G +A + G+ A G+ W Sbjct: 62 HGDVFTVHLGPRPVVVLCGTQTIREALVDHAEAFSGRGTIAAAQLVMQDYGIFFASGQRW 121 Query: 241 RVRRRAIVPSLHQ-----KFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTL 405 + RR + ++ + + V E I + + L E+L K +G ++ LF +T Sbjct: 122 KTLRRFSLATMKEFGMGKRSVEERI---KEEAQCLVEELKK--YQGVPLDPTFLFQCITA 176 Query: 406 DVIGKAVFNYDFD 444 ++I VF FD Sbjct: 177 NIICSIVFGERFD 189
>CP6A8_DROME (Q27593) Cytochrome P450 6a8 (EC 1.14.-.-) (CYPVIA8)| Length = 506 Score = 43.1 bits (100), Expect = 5e-04 Identities = 32/120 (26%), Positives = 53/120 (44%), Gaps = 1/120 (0%) Frame = +1 Query: 94 PKSFVIVSDPDIAKHIL-RDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVRRRAIVPS 270 P +FVI D ++AK IL +D S +KGI + + L DG WR+ R + + Sbjct: 82 PAAFVI--DLELAKQILIKDFSNFSNKGIFYNEKDDPISAHLFNLDGAQWRLLRNKLSST 139 Query: 271 LHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVFNYDFDSL 450 + M + + + + ++E+ L +R T+DVIG F +SL Sbjct: 140 FTSGKMKLMYPTVVSVANEFMTVMHEKVPKNSVLEIRDLVARFTVDVIGTCAFGIQCNSL 199
>CP2F2_MOUSE (P33267) Cytochrome P450 2F2 (EC 1.14.14.-) (CYPIIF2) (Naphthalene| dehydrogenase) (Naphthalene hydroxylase) (P450-NAH-2) Length = 491 Score = 43.1 bits (100), Expect = 5e-04 Identities = 32/137 (23%), Positives = 59/137 (43%), Gaps = 10/137 (7%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYS-KGILAEILEFVMGTGLIPADGEVW 240 +G +F + LG + +++S K L D + +S +G F G G+ +DGE W Sbjct: 62 YGSVFTVYLGSRPVIVLSGYQTVKEALVDKGEEFSGRGAYPVFFNFTRGNGIAFSDGERW 121 Query: 241 RVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAA---------EGEIVEMESLFS 393 ++ RR F +++ FG + E++ + + EG+ + + S Sbjct: 122 KILRR---------FSVQILRNFGMGKRSIEERILEEGSFLLEVLRKMEGKPFDPVFILS 172 Query: 394 RLTLDVIGKAVFNYDFD 444 R ++I VF FD Sbjct: 173 RSVSNIICSVVFGSRFD 189
>CP2B2_RAT (P04167) Cytochrome P450 2B2 (EC 1.14.14.1) (CYPIIB2) (P450E) (P450| PB4) Length = 491 Score = 43.1 bits (100), Expect = 5e-04 Identities = 37/133 (27%), Positives = 67/133 (50%), Gaps = 6/133 (4%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYS-KGILAEILEFVMGTGLIPADGEVW 240 +G +F ++LGP+ V++ D K L ++ +S +G +A I G+I A+GE W Sbjct: 62 YGDVFTVHLGPRPVVMLCGTDTIKEALVGQAEDFSGRGTIAVIEPIFKEYGVIFANGERW 121 Query: 241 RVRRRAIVPSLH-----QKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTL 405 + RR + ++ ++ V E I + + L E+L K ++G ++ LF +T Sbjct: 122 KALRRFSLATMRDFGMGKRSVEERI---QEEAQCLVEELRK--SQGAPLDPTFLFQCITA 176 Query: 406 DVIGKAVFNYDFD 444 ++I VF FD Sbjct: 177 NIICSIVFGERFD 189
>CP2B1_RAT (P00176) Cytochrome P450 2B1 (EC 1.14.14.1) (CYPIIB1) (P450-B)| (P450b) (P450-PB1 and P450-PB2) (P450-LM2) Length = 491 Score = 43.1 bits (100), Expect = 5e-04 Identities = 37/133 (27%), Positives = 67/133 (50%), Gaps = 6/133 (4%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYS-KGILAEILEFVMGTGLIPADGEVW 240 +G +F ++LGP+ V++ D K L ++ +S +G +A I G+I A+GE W Sbjct: 62 YGDVFTVHLGPRPVVMLCGTDTIKEALVGQAEDFSGRGTIAVIEPIFKEYGVIFANGERW 121 Query: 241 RVRRRAIVPSLH-----QKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTL 405 + RR + ++ ++ V E I + + L E+L K ++G ++ LF +T Sbjct: 122 KALRRFSLATMRDFGMGKRSVEERI---QEEAQCLVEELRK--SQGAPLDPTFLFQCITA 176 Query: 406 DVIGKAVFNYDFD 444 ++I VF FD Sbjct: 177 NIICSIVFGERFD 189
>C6A18_DROME (Q9VB31) Probable cytochrome P450 6a18 (EC 1.14.-.-) (CYPVIA18)| Length = 507 Score = 43.1 bits (100), Expect = 5e-04 Identities = 35/126 (27%), Positives = 55/126 (43%), Gaps = 1/126 (0%) Frame = +1 Query: 76 FRLNLGPKSFVIVSDPDIAKHILRDNSKAYS-KGILAEILEFVMGTGLIPADGEVWRVRR 252 F L P +FVI D ++AK IL N ++ KGI + M L DG WR+ R Sbjct: 76 FYLFQKPAAFVI--DLELAKQILIKNFSNFTDKGIYYNEKDDPMSAHLFNLDGPQWRLLR 133 Query: 253 RAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVFN 432 + + + M + + + +E I+++ L +R T+DVIG F Sbjct: 134 SKLSSTFTSGKMKFMYPTVVSVAEEFMAVMHEKVSENSILDVRDLVARFTVDVIGTCAFG 193 Query: 433 YDFDSL 450 +SL Sbjct: 194 IKCNSL 199
>CP4P1_DROME (Q9V558) Cytochrome P450 4p1 (EC 1.14.-.-) (CYPIVP1)| Length = 513 Score = 43.1 bits (100), Expect = 5e-04 Identities = 29/146 (19%), Positives = 61/146 (41%) Frame = +1 Query: 97 KSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVRRRAIVPSLH 276 K+ + D D A+++L ++ +KG++ L + TGL+ + G+ W RR+ + P+ H Sbjct: 91 KAIYNIIDADSAENVL-NHPNLITKGLVYNFLHPFLRTGLLTSTGKKWHARRKMLTPTFH 149 Query: 277 QKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVFNYDFDSLSY 456 + + +F S + L + + + + R TL+ I + D ++ Sbjct: 150 FNILNQFQEIFKTESQKFL--LQFEGQDEVTITLHDVIPRFTLNSICETAMGVKLDEMAE 207 Query: 457 DNGMVEAVYVTLREAEMRSTSPIPTW 534 + + E +R S W Sbjct: 208 KGDRYRENFSQIEECFIRRLSNPLLW 233
>CP3AF_CAVPO (Q64406) Cytochrome P450 3A15 (EC 1.14.14.1) (CYPIIIA15)| Length = 503 Score = 42.7 bits (99), Expect = 7e-04 Identities = 27/130 (20%), Positives = 61/130 (46%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWR 243 +G ++ L GP+ + +++PD+ K +L + + + M + ++ E W+ Sbjct: 68 YGNMWGLYDGPQPVLAITEPDMIKAVLVKECYSVFTNRRSLVPVGFMKKSVSLSEDEEWK 127 Query: 244 VRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKA 423 R + P+ + EM + + L + L + A +G+ V+++ +F +D+I Sbjct: 128 RIRTQLSPNFTSGKLKEMFPIIKQYGDVLVKNLRQEAEKGKPVQLKEIFGAYGMDIIIAT 187 Query: 424 VFNYDFDSLS 453 F + DSL+ Sbjct: 188 AFGVNVDSLN 197
>CP4C3_DROME (Q9VA27) Cytochrome P450 4c3 (EC 1.14.-.-) (CYPIVC3)| Length = 535 Score = 42.7 bits (99), Expect = 7e-04 Identities = 35/142 (24%), Positives = 67/142 (47%), Gaps = 1/142 (0%) Frame = +1 Query: 61 THGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVW 240 T G+ R+ G V++ +P+ + IL ++ K +K + L +G GL+ + W Sbjct: 93 TRIGINRVWQGTAPRVLLFEPETVEPIL-NSQKFVNKSHDYDYLHPWLGEGLLTSTDRKW 151 Query: 241 RVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGK 420 RR+ + P+ H K + + I +F + S L KL E + + TLD++ + Sbjct: 152 HSRRKILTPAFHFKILDDFIDVFNEQSAVLARKL-AVEVGSEAFNLFPYVTLCTLDIVCE 210 Query: 421 -AVFNYDFDSLSYDNGMVEAVY 483 A+ + + ++ V+AVY Sbjct: 211 TAMGRRIYAQSNSESEYVKAVY 232
>C4D14_DROME (O46051) Probable cytochrome P450 4d14 (EC 1.14.-.-) (CYPIVD14)| Length = 507 Score = 42.7 bits (99), Expect = 7e-04 Identities = 26/111 (23%), Positives = 50/111 (45%) Frame = +1 Query: 88 LGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVRRRAIVP 267 LG F+ I + + + K L +L +G GL+ + G+ W RR+ I P Sbjct: 76 LGESGFMTADSKMI--EAIMSSQQTIQKNNLYSLLVNWLGDGLLISQGKKWFRRRKIITP 133 Query: 268 SLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGK 420 + H K + + + +F + S + +KL A ++ M + +D+I + Sbjct: 134 AFHFKILEDFVEVFDQQSATMVQKLYDRADGKTVINMFPVACLCAMDIIAE 184
>C6A21_DROME (Q9V774) Probable cytochrome P450 6a21 (EC 1.14.-.-) (CYPVIA21)| Length = 504 Score = 42.4 bits (98), Expect = 0.001 Identities = 29/116 (25%), Positives = 49/116 (42%), Gaps = 1/116 (0%) Frame = +1 Query: 106 VIVSDPDIAKHIL-RDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVRRRAIVPSLHQK 282 V V + +AK IL ++ +K +G + + L DG+ WR R + + Sbjct: 83 VFVLETSLAKQILIKEFNKFTDRGFFHNPEDDPLSGQLFLLDGQKWRTMRNKLSSTFTSG 142 Query: 283 FVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVFNYDFDSL 450 + M K + + + A+ +VE+ L +R T DVIG F + SL Sbjct: 143 KMKYMFPTVVKVANEFTDVFGQNVAKSPVVEVRELLARFTTDVIGTCAFGIECSSL 198
>C13A5_CAEEL (Q27514) Putative cytochrome P450 CYP13A5 (EC 1.14.-.-)| Length = 520 Score = 42.4 bits (98), Expect = 0.001 Identities = 32/142 (22%), Positives = 61/142 (42%), Gaps = 3/142 (2%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILR---DNSKAYSKGILAEILEFVMGTGLIPADGE 234 +G ++ + G + +IVS+P+ + DN + L+ A G Sbjct: 64 YGPIYGITEGVEKTLIVSNPEFVHEVFVKQFDNFYGRKTNPIQGDPNKNKRAHLVSAQGH 123 Query: 235 VWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVI 414 W+ R P+ K + +++ + L LD A+A+G+ V++ + TLD+I Sbjct: 124 RWKRLRTLSSPTFSNKNLRKIMSTVEETVVELMRHLDDASAKGKAVDLLDYYQEFTLDII 183 Query: 415 GKAVFNYDFDSLSYDNGMVEAV 480 G+ +SL + N M+ V Sbjct: 184 GRIAMG-QTESLMFRNPMLPKV 204
>C13A3_CAEEL (Q27517) Putative cytochrome P450 CYP13A3 (EC 1.14.-.-)| Length = 520 Score = 42.4 bits (98), Expect = 0.001 Identities = 30/151 (19%), Positives = 64/151 (42%), Gaps = 3/151 (1%) Frame = +1 Query: 37 LPLYDHFLTHGGLFRLNLGPKSFVIVSDPDIAKHILR---DNSKAYSKGILAEILEFVMG 207 L L D +G ++ G + ++VSDP+ + DN A + L + Sbjct: 55 LRLGDWTKEYGPMYGFTDGVEKTLVVSDPEFVHEVFVKQFDNFYARKQNPLQGDPDKDPR 114 Query: 208 TGLIPADGEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESL 387 L+ + G W+ R P+ K + ++ ++ + L+K A G+ +++ Sbjct: 115 IHLVTSQGHRWKRLRTLASPTFSNKSLRKIFSTVEESVAEMMRHLEKGTAGGKTIDILEY 174 Query: 388 FSRLTLDVIGKAVFNYDFDSLSYDNGMVEAV 480 + T+D+IGK S+ ++N ++ + Sbjct: 175 YQEFTMDIIGKIAMGQS-GSMMFENPWLDKI 204
>CP46A_MOUSE (Q9WVK8) Cytochrome p450 46A1 (EC 1.14.13.98) (Cholesterol| 24-hydroxylase) (CH24H) Length = 500 Score = 42.4 bits (98), Expect = 0.001 Identities = 33/135 (24%), Positives = 64/135 (47%), Gaps = 6/135 (4%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHIL-----RDNSKAYSKGILAEILEFVMGTGLI-PA 225 +G + R+N+ K+ VIV+ P+ K L +SK Y + + E + G GL+ Sbjct: 71 YGPVVRVNVFYKTSVIVTSPESVKKFLMSTKYNKDSKMY-RALQTVFGERLFGQGLVSEC 129 Query: 226 DGEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTL 405 D W +R+ + + + + ++ F + + +L E L+ A V M+ + + T+ Sbjct: 130 DYGRWYKQRKVMDLAFSRSSLVSLMETFNEKAEQLVEILEAKADGQTPVSMQDMLTCATI 189 Query: 406 DVIGKAVFNYDFDSL 450 D++ KA F + L Sbjct: 190 DILAKAAFGMETSML 204
>CP3AP_MOUSE (O09158) Cytochrome P450 3A25 (EC 1.14.14.1) (CYPIIIA25)| Length = 503 Score = 42.4 bits (98), Expect = 0.001 Identities = 30/136 (22%), Positives = 62/136 (45%), Gaps = 1/136 (0%) Frame = +1 Query: 49 DHFLTHGGLFRLNLGPKSFVIVSDPDIAKHIL-RDNSKAYSKGILAEILEFVMGTGLIPA 225 D + +G ++ GP+ + + DP+I K +L ++ ++ + F M + + Sbjct: 63 DCYKKYGKIWGFYEGPQPILAIMDPEIIKIVLVKECYSVFTNRRFFGPVGF-MKKAITIS 121 Query: 226 DGEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTL 405 + E W+ R + P+ + EM + + L L + +GE + M+ +F ++ Sbjct: 122 EDEEWKRLRTLLSPTFTSGKLKEMFPIMRQYGDILVRNLRREEEKGEPISMKDIFGAYSM 181 Query: 406 DVIGKAVFNYDFDSLS 453 DVI F + DSL+ Sbjct: 182 DVITGTSFGVNVDSLN 197
>CP4E2_DROME (Q27606) Cytochrome P450 4e2 (EC 1.14.-.-) (CYPIVE2)| Length = 526 Score = 42.4 bits (98), Expect = 0.001 Identities = 32/147 (21%), Positives = 63/147 (42%), Gaps = 1/147 (0%) Frame = +1 Query: 88 LGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVRRRAIVP 267 +G S V+V+ + IL + +K + ++ +G GL+ + G W R+ I P Sbjct: 75 IGTYSNVLVTSSKYLEFILSSQT-LITKSDIYQLTHPWLGLGLLTSTGSKWHKHRKMITP 133 Query: 268 SLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVFNYDFDS 447 + H + + + + S + + L AA I + + LTLDVI ++ Sbjct: 134 AFHFNILQDFHEVMNENSTKFIKHLKTVAAGDNIFDFQEQAHYLTLDVICDTAMGVSINA 193 Query: 448 L-SYDNGMVEAVYVTLREAEMRSTSPI 525 + + + +V+A MR+ P+ Sbjct: 194 MENRSSSIVQAFKDMCYNINMRAFHPL 220
>CP3A9_RAT (P51538) Cytochrome P450 3A9 (EC 1.14.14.1) (CYPIIIA9) (P450-OLF3)| (Olfactive) (3AH15) Length = 503 Score = 42.0 bits (97), Expect = 0.001 Identities = 33/140 (23%), Positives = 62/140 (44%), Gaps = 10/140 (7%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSK----------GILAEILEFVMGTG 213 +G L+ L G + + ++DPDI K +L + YS GIL + + Sbjct: 68 YGKLWGLYDGRQPVLAITDPDIIKTVLV--KECYSTFTNRRNFGPVGILKKAISI----- 120 Query: 214 LIPADGEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFS 393 ++ E W+ R + P+ + EM + + + L + + + EG+ M+ +F Sbjct: 121 ---SEDEEWKRIRALLSPTFTSGKLKEMFPIINQYTDMLVRNMRQGSEEGKPTSMKDIFG 177 Query: 394 RLTLDVIGKAVFNYDFDSLS 453 ++DVI F + DSL+ Sbjct: 178 AYSMDVITATSFGVNVDSLN 197
>CP6A9_DROME (Q27594) Cytochrome P450 6a9 (EC 1.14.-.-) (CYPVIA9)| Length = 504 Score = 42.0 bits (97), Expect = 0.001 Identities = 35/146 (23%), Positives = 59/146 (40%), Gaps = 1/146 (0%) Frame = +1 Query: 16 RPGXAIFLPLYDHFLTHGGLFRLNLGPKSFVIVSDPDIAKHIL-RDNSKAYSKGILAEIL 192 R AI++ Y+ F G + ++V D +AK IL ++ +K +G Sbjct: 53 RSFSAIWMDYYNKFRGTGPFAGFYWFQRPGILVLDISLAKLILIKEFNKFTDRGFYHNTE 112 Query: 193 EFVMGTGLIPADGEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIV 372 + + L DG+ W+ R + + + M K E +A + IV Sbjct: 113 DDPLSGQLFLLDGQKWKSMRSKLSYTFTSGKMKYMFPTVVKVGHEFIEVFGQAMEKSPIV 172 Query: 373 EMESLFSRLTLDVIGKAVFNYDFDSL 450 E+ + +R T DVIG F + SL Sbjct: 173 EVRDILARFTTDVIGTCAFGIECSSL 198
>C505_FUSOX (Q9Y8G7) Bifunctional P-450:NADPH-P450 reductase (Fatty acid| omega-hydroxylase) (P450foxy) [Includes: Cytochrome P450 505 (EC 1.14.14.1); NADPH--cytochrome P450 reductase (EC 1.6.2.4)] Length = 1066 Score = 42.0 bits (97), Expect = 0.001 Identities = 41/159 (25%), Positives = 69/159 (43%), Gaps = 5/159 (3%) Frame = +1 Query: 61 THGGLFRLNLGPKSFVIVSDPDIAKHILRDNS-KAYSKGILAEILEFVMGTGLIPA--DG 231 T+G +FRL LG K+ + VS + + + K K +L+++ E V GL A D Sbjct: 36 TYGPIFRLRLGAKAPIFVSSNSLINEVCDEKRFKKTLKSVLSQVREGV-HDGLFTAFEDE 94 Query: 232 EVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDV 411 W R +VP+ + M + +LC K + I + F+RL LD Sbjct: 95 PNWGKAHRILVPAFGPLSIRGMFPEMHDIATQLCMKFARHGPRTPI-DTSDNFTRLALDT 153 Query: 412 IGKAVFNYDFDSLSYD--NGMVEAVYVTLREAEMRSTSP 522 + ++ F S + + +EA+ L E+ R+ P Sbjct: 154 LALCAMDFRFYSYYKEELHPFIEAMGDFLTESGNRNRRP 192
>C71AR_ARATH (O65438) Cytochrome P450 71A27 (EC 1.14.-.-)| Length = 499 Score = 42.0 bits (97), Expect = 0.001 Identities = 31/128 (24%), Positives = 59/128 (46%), Gaps = 4/128 (3%) Frame = +1 Query: 43 LYDHFLTHGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTG--- 213 L+ L +G L L+ G ++VS PD+ I++ + ++ ++ + M G Sbjct: 57 LHSLSLRYGPLMLLHFGRVPVLVVSCPDVTNDIMKTHDLKFANRPKSKAINIFMEGGRDI 116 Query: 214 LIPADGEVWR-VRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLF 390 + GE W+ ++ +V L+ K V L + + EKL++A++ V + L Sbjct: 117 IFGPYGEDWKSMKSLGVVHLLNNKMVRSFENLREEEIKVMTEKLEEASSSSSSVNLSKLL 176 Query: 391 SRLTLDVI 414 LT D+I Sbjct: 177 MTLTNDII 184
>CP132_MYCTU (P77900) Putative cytochrome P450 132 (EC 1.14.-.-)| Length = 461 Score = 41.6 bits (96), Expect = 0.002 Identities = 29/124 (23%), Positives = 49/124 (39%) Frame = +1 Query: 79 RLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVRRRA 258 R + FV +S PD H+L + Y K + G L+ +G+ W R A Sbjct: 48 RFRCAGRRFVSISHPDYVDHVLHEARLKYVKSDEYGPIRATAGLNLLTDEGDSWARHRGA 107 Query: 259 IVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVFNYD 438 + + ++ + ++GL + A G +M TL V+ A+F+ D Sbjct: 108 LNSTFARRHLRGLVGLMIDP----IADVTAARVPGAQFDMHQSMVETTLRVVANALFSQD 163 Query: 439 FDSL 450 F L Sbjct: 164 FGPL 167
>CP132_MYCBO (P59954) Putative cytochrome P450 132 (EC 1.14.-.-)| Length = 461 Score = 41.6 bits (96), Expect = 0.002 Identities = 29/124 (23%), Positives = 49/124 (39%) Frame = +1 Query: 79 RLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVRRRA 258 R + FV +S PD H+L + Y K + G L+ +G+ W R A Sbjct: 48 RFRCAGRRFVSISHPDYVDHVLHEARLKYVKSDEYGPIRATAGLNLLTDEGDSWARHRGA 107 Query: 259 IVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVFNYD 438 + + ++ + ++GL + A G +M TL V+ A+F+ D Sbjct: 108 LNSTFARRHLRGLVGLMIDP----IADVTAALVPGAQFDMHQSMVETTLRVVANALFSQD 163 Query: 439 FDSL 450 F L Sbjct: 164 FGPL 167
>CP3A6_RABIT (P11707) Cytochrome P450 3A6 (EC 1.14.14.1) (CYPIIIA6) (P450-3C)| Length = 501 Score = 41.6 bits (96), Expect = 0.002 Identities = 31/133 (23%), Positives = 64/133 (48%), Gaps = 4/133 (3%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEF----VMGTGLIPADG 231 +G ++ L G + ++++DPD+ K +L + YS + F M + ++ Sbjct: 66 YGKMWGLFDGRQPLMVITDPDMIKTVLV--KECYS--VFTNRRSFGPVGFMKKAVSISED 121 Query: 232 EVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDV 411 E W+ R + P+ + EM+ + + L + L + A +G+ V+++ +F ++DV Sbjct: 122 EDWKRVRTLLSPTFTSGKLKEMLPIIAQYGDVLVKNLRQEAEKGKPVDLKEIFGAYSMDV 181 Query: 412 IGKAVFNYDFDSL 450 I F + DSL Sbjct: 182 ITGTSFGVNIDSL 194
>CP2BA_MOUSE (P12791) Cytochrome P450 2B10 (EC 1.14.14.1) (CYPIIB10)| (Testosterone 16-alpha hydroxylase) (P450-16-alpha) (Clone PF3/46) Length = 500 Score = 41.6 bits (96), Expect = 0.002 Identities = 36/133 (27%), Positives = 68/133 (51%), Gaps = 6/133 (4%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYS-KGILAEILEFVMGTGLIPADGEVW 240 +G +F ++LGP+ V++ D + L ++A+S +G +A + G+I A+GE W Sbjct: 62 YGDVFTVHLGPRPVVMLCGTDTIREALVGQAEAFSGRGTVAVVEPTFKEYGVIFANGERW 121 Query: 241 RVRRRAIVPSLH-----QKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTL 405 + RR + ++ ++ V E I + + L E+L K ++G ++ LF +T Sbjct: 122 KTLRRFSLATMRDFGMGKRSVEERI---QEEAQCLVEELRK--SQGAPLDPTFLFQCITA 176 Query: 406 DVIGKAVFNYDFD 444 +VI VF F+ Sbjct: 177 NVICSIVFGERFE 189
>CYPE_BACSU (O08336) Probable bifunctional P-450:NADPH-P450 reductase 2| [Includes: Cytochrome P450 102 (EC 1.14.14.1); NADPH--cytochrome P450 reductase (EC 1.6.2.4)] Length = 1054 Score = 41.6 bits (96), Expect = 0.002 Identities = 43/155 (27%), Positives = 71/155 (45%), Gaps = 6/155 (3%) Frame = +1 Query: 67 GGLFRLNLGPKSFVIVSDPDIAKHILRDN--SKAYSKGILAEILEFVMGTGLIPA--DGE 234 G +FR + S V VS ++ + + K KG L ++ EF G GL + Sbjct: 39 GPIFRFDFPGVSSVFVSGHNLVAEVCDEKRFDKNLGKG-LQKVREFG-GDGLFTSWTHEP 96 Query: 235 VWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVI 414 W+ R ++PS QK + + + +L +K + EI + + +RLTLD I Sbjct: 97 NWQKAHRILLPSFSQKAMKGYHSMMLDIATQLIQKWSRLNPNEEIDVADDM-TRLTLDTI 155 Query: 415 GKAVFNYDFDSLSYD--NGMVEAVYVTLREAEMRS 513 G FNY F+S D + + ++ L+EA +S Sbjct: 156 GLCGFNYRFNSFYRDSQHPFITSMLRALKEAMNQS 190
>CP2F5_GORGO (Q8WNE1) Cytochrome P450 2F5 (EC 1.14.14.1) (CYPIIF5) (CYP4502F5)| Length = 491 Score = 41.6 bits (96), Expect = 0.002 Identities = 31/137 (22%), Positives = 59/137 (43%), Gaps = 10/137 (7%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYS-KGILAEILEFVMGTGLIPADGEVW 240 +G ++ ++LGP+ V++S K L D + +S + F G G+ ++G+ W Sbjct: 62 YGSMYTVHLGPRRVVVLSGYQAVKEALVDQGEEFSGRRDFPAFFNFTKGNGIAFSNGDRW 121 Query: 241 RVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKL---------DKAAAEGEIVEMESLFS 393 +V RR F +++ FG + E++ + EGE + + S Sbjct: 122 KVLRR---------FSIQILRNFGMGKRSIEERILEEGSFLLAELRKTEGEPFDPTFVLS 172 Query: 394 RLTLDVIGKAVFNYDFD 444 R ++I +F FD Sbjct: 173 RSVSNIICSVLFGSRFD 189
>CP2BK_MOUSE (Q62397) Cytochrome P450 2B20 (EC 1.14.14.1) (CYPIIB20) (P24)| (Fragment) Length = 470 Score = 41.2 bits (95), Expect = 0.002 Identities = 35/133 (26%), Positives = 68/133 (51%), Gaps = 6/133 (4%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYS-KGILAEILEFVMGTGLIPADGEVW 240 +G +F ++LGP+ V++ D + L ++A+S +G +A + G+I A+GE W Sbjct: 62 YGDVFTVHLGPRPVVMLCGTDTIREALVGQAEAFSGRGTVAVVEPTFKEYGVIFANGERW 121 Query: 241 RVRRRAIVPSLH-----QKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTL 405 + RR + ++ ++ V E I + + L E+L K ++G ++ LF +T Sbjct: 122 KTLRRFSLATMRDFGMGKRSVEERI---QEEAQCLVEELRK--SQGAPLDPTFLFQCITA 176 Query: 406 DVIGKAVFNYDFD 444 ++I VF F+ Sbjct: 177 NIICSIVFGERFE 189
>C340_ORYLA (Q98T91) Cytochrome P450 3A40 (EC 1.14.14.1)| Length = 502 Score = 41.2 bits (95), Expect = 0.002 Identities = 21/77 (27%), Positives = 37/77 (48%) Frame = +1 Query: 223 ADGEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLT 402 A+ + W+ R + PS + EM + S L + + K + E +EM+ F + Sbjct: 121 AEDDQWKRIRSVLSPSFTSGRLKEMFDIMKHHSANLIQSMKKKVDKDEPLEMKEYFGPYS 180 Query: 403 LDVIGKAVFNYDFDSLS 453 +DV+ F+ D DSL+ Sbjct: 181 MDVVTSTAFSVDIDSLN 197
>C71AG_ARATH (Q9FH66) Cytochrome P450 71A16 (EC 1.14.-.-)| Length = 497 Score = 41.2 bits (95), Expect = 0.002 Identities = 34/158 (21%), Positives = 64/158 (40%), Gaps = 4/158 (2%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTG---LIPADGE 234 HG L L G +IVS D+A +++ + ++ + + + G + GE Sbjct: 63 HGPLMLLRFGRVPVLIVSSADVAHDVMKTHDLKFANRPITKSAHKISNGGRDLVFAPYGE 122 Query: 235 VWR-VRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDV 411 WR V+ + L K V + L E L++A+ V + L + + D+ Sbjct: 123 YWRNVKSLCTIHLLSNKMVQSSEKRREEEITLLMETLEEASLSSSSVNLSKLITNMVSDI 182 Query: 412 IGKAVFNYDFDSLSYDNGMVEAVYVTLREAEMRSTSPI 525 +GK V + S + G ++ +T + SP+ Sbjct: 183 MGKVVLGKKY---SGEEGTIDVKTITKSFLDAVGLSPV 217
>CP52M_DEBHA (Q9Y758) Cytochrome P450 52A13 (EC 1.14.14.-) (Alkane hydroxylase| 2) (Alkane-inducible p450alk 2) (DH-ALK2) Length = 519 Score = 40.8 bits (94), Expect = 0.003 Identities = 28/115 (24%), Positives = 52/115 (45%) Frame = +1 Query: 106 VIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVRRRAIVPSLHQKF 285 +I DP+ K +L ++ G + ++G G+ DG W+ R + P ++ Sbjct: 98 IITRDPENMKAVLATQFNDFALGTRHAHFKPLLGDGIFTLDGNGWKQSRSMLRPQFSREQ 157 Query: 286 VTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVFNYDFDSL 450 V + L RL + + A+GE + ++ LF +LT+D + +F SL Sbjct: 158 VAHVQALEPHLQ-RLAKHI--RLADGETINIQDLFFKLTVDTATEFLFGQSVYSL 209
>CP3AD_MOUSE (Q64464) Cytochrome P450 3A13 (EC 1.14.14.1) (CYPIIIA13)| Length = 503 Score = 40.8 bits (94), Expect = 0.003 Identities = 31/138 (22%), Positives = 61/138 (44%), Gaps = 8/138 (5%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRD-------NSKAYSK-GILAEILEFVMGTGLI 219 +G ++ L G + + ++DPDI K +L N + + GIL + + Sbjct: 68 YGKMWGLYDGRQPVLAITDPDIIKTVLVKECYSTFTNRRRFGPVGILKKAISI------- 120 Query: 220 PADGEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRL 399 ++ E W+ R + P+ + EM + + + L + + EG+ M+ +F Sbjct: 121 -SENEEWKRIRALLSPTFTSGRLKEMFPIINQFTDVLVRNMRQGLGEGKPTSMKDIFGAY 179 Query: 400 TLDVIGKAVFNYDFDSLS 453 ++DVI F + DSL+ Sbjct: 180 SMDVITATSFGVNIDSLN 197
>CP4D1_DROSI (O16805) Cytochrome P450 4d1 (EC 1.14.-.-) (CYPIVD1)| Length = 512 Score = 40.4 bits (93), Expect = 0.004 Identities = 26/90 (28%), Positives = 45/90 (50%), Gaps = 3/90 (3%) Frame = +1 Query: 88 LGPKSFVIVSDP---DIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVRRRA 258 LGP+ V++ +P ++ LR N KA + LE + GL+ + G W RR+ Sbjct: 78 LGPELNVLMGNPKDVEVVLGTLRFNDKAGEY----KALEPWLKEGLLVSRGRKWHKRRKI 133 Query: 259 IVPSLHQKFVTEMIGLFGKASGRLCEKLDK 348 I P+ H K + + + +F K S L +++ Sbjct: 134 ITPAFHFKILDQFVDVFEKGSRDLLRNMEQ 163
>CP3A4_HUMAN (P08684) Cytochrome P450 3A4 (EC 1.14.13.67) (Quinine| 3-monooxygenase) (CYPIIIA4) (Nifedipine oxidase) (Taurochenodeoxycholate 6-alpha-hydroxylase) (EC 1.14.13.97) (NF-25) (P450-PCN1) Length = 502 Score = 40.4 bits (93), Expect = 0.004 Identities = 30/125 (24%), Positives = 57/125 (45%), Gaps = 4/125 (3%) Frame = +1 Query: 91 GPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEF----VMGTGLIPADGEVWRVRRRA 258 G + + ++DPD+ K +L + YS + F M + + A+ E W+ R Sbjct: 76 GQQPVLAITDPDMIKTVLV--KECYS--VFTNRRPFGPVGFMKSAISIAEDEEWKRLRSL 131 Query: 259 IVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVFNYD 438 + P+ + EM+ + + L L + A G+ V ++ +F ++DVI F + Sbjct: 132 LSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVN 191 Query: 439 FDSLS 453 DSL+ Sbjct: 192 IDSLN 196
>CP52E_CANMA (P24458) Cytochrome P450 52A5 (EC 1.14.14.-) (CYPLIIA5)| (Alkane-inducible P450-ALK2-A) (CYP52A3-B) Length = 523 Score = 40.4 bits (93), Expect = 0.004 Identities = 35/146 (23%), Positives = 62/146 (42%), Gaps = 6/146 (4%) Frame = +1 Query: 40 PLYDHFLTHGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLI 219 P + ++T G+ ++ V+ DP+ K +L ++ G + ++G G+ Sbjct: 86 PHHSFYMTVAGMLKI-------VLTVDPENIKAVLATQFNDFALGARHAHFDPLLGDGIF 138 Query: 220 PADGEVWRVRRRAIVPSL------HQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEME 381 DGE W+ R + P H K + + + K KL+K GE +++ Sbjct: 139 TLDGEGWKHSRAMLRPQFAREQIAHVKALEPHVQVLAKQI-----KLNK----GETFDLQ 189 Query: 382 SLFSRLTLDVIGKAVFNYDFDSLSYD 459 LF R T+D + +F SL YD Sbjct: 190 ELFFRFTVDTATEFLFGESVHSL-YD 214
>CP3AH_CAVPO (Q64409) Cytochrome P450 3A17 (EC 1.14.14.1) (CYPIIIA17)| Length = 503 Score = 40.0 bits (92), Expect = 0.005 Identities = 27/130 (20%), Positives = 59/130 (45%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWR 243 +G ++ L GP+ + +++PD+ K +L + + M L + E W+ Sbjct: 68 YGNMWGLYDGPRPVLSITEPDMIKAVLVKECYSVFTNRRSIFPAGFMKKALSISKDEEWK 127 Query: 244 VRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKA 423 R + + + EM + + L + L + A +G+ V+++ +F ++D+I Sbjct: 128 RIRTQLSQNFTSGKLKEMFPIIKQYGDVLVKNLRQEAEKGKPVQLKEIFGAYSMDIIIAT 187 Query: 424 VFNYDFDSLS 453 F + DSL+ Sbjct: 188 AFGVNVDSLN 197
>CP4D1_DROME (P33269) Cytochrome P450 4d1 (EC 1.14.-.-) (CYPIVD1)| Length = 512 Score = 40.0 bits (92), Expect = 0.005 Identities = 26/90 (28%), Positives = 45/90 (50%), Gaps = 3/90 (3%) Frame = +1 Query: 88 LGPKSFVIVSDP---DIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVRRRA 258 LGP+ V++ +P ++ LR N KA + LE + GL+ + G W RR+ Sbjct: 78 LGPELNVLMGNPKDVEVVLGTLRFNDKAGEY----KALEPWLKEGLLVSRGRKWHKRRKI 133 Query: 259 IVPSLHQKFVTEMIGLFGKASGRLCEKLDK 348 I P+ H K + + + +F K S L +++ Sbjct: 134 ITPAFHFKILDQFVEVFEKGSRDLLRNMEQ 163
>C13A1_CAEEL (Q27520) Putative cytochrome P450 CYP13A1 (EC 1.14.-.-)| Length = 519 Score = 40.0 bits (92), Expect = 0.005 Identities = 30/141 (21%), Positives = 58/141 (41%), Gaps = 3/141 (2%) Frame = +1 Query: 67 GGLFRLNLGPKSFVIVSDPDIAKHIL---RDNSKAYSKGILAEILEFVMGTGLIPADGEV 237 G ++ G +++SDP++ + DN + + E T L A G Sbjct: 66 GKIYGFTEGTLKTLVISDPELVHEVFVTQYDNFYGRKRNPIQGDSEKEKRTNLFAAQGFR 125 Query: 238 WRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIG 417 W+ R P+ + ++ ++ L ++K +A G+ ++M + TLDVIG Sbjct: 126 WKRLRAISSPTFSNSSLRKLYQTVEDSALELLRHIEKQSAGGKQIDMLKFYQEFTLDVIG 185 Query: 418 KAVFNYDFDSLSYDNGMVEAV 480 + DS + N ++ V Sbjct: 186 RIAMG-QTDSQMFKNPIMPIV 205
>C13A8_CAEEL (Q27516) Putative cytochrome P450 CYP13A8 (EC 1.14.-.-)| Length = 509 Score = 40.0 bits (92), Expect = 0.005 Identities = 29/142 (20%), Positives = 60/142 (42%), Gaps = 3/142 (2%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHIL---RDNSKAYSKGILAEILEFVMGTGLIPADGE 234 +G ++ G + +++SDPD+ + IL DN + + ++ A G Sbjct: 59 YGKIYGFTEGMQKVMVISDPDLVQEILVKQYDNFYGRKHNPVQGDPDKDKDIHIVGAQGF 118 Query: 235 VWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVI 414 W+ R P+ + +++ ++ L +KL + + G+ V M + T DVI Sbjct: 119 RWKRLRTITAPAFSNGSIKKVLTTMEDSTQELMKKLREESENGKAVNMHLFYQEYTFDVI 178 Query: 415 GKAVFNYDFDSLSYDNGMVEAV 480 + DS + N +++ V Sbjct: 179 SRVAMGQP-DSQMFKNPLLKDV 199
>CP312_DROME (Q9VVN6) Probable cytochrome P450 312a1 (EC 1.14.-.-) (CYPCCCXIIA1)| Length = 510 Score = 40.0 bits (92), Expect = 0.005 Identities = 22/81 (27%), Positives = 37/81 (45%) Frame = +1 Query: 211 GLIPADGEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLF 390 GL + E W RR+ ++P+ + + + + +F K S L + K A G+ ++ L Sbjct: 118 GLFTSGFEKWSHRRKIVMPAFNYTMIKQFVAVFEKQSRILLTNVAKFAESGDQIDFLQLI 177 Query: 391 SRLTLDVIGKAVFNYDFDSLS 453 S TLD I + S S Sbjct: 178 SCFTLDTICETALGVSVGSQS 198
>C82A4_SOYBN (O49859) Cytochrome P450 82A4 (EC 1.14.-.-) (P450 CP9)| Length = 525 Score = 39.7 bits (91), Expect = 0.006 Identities = 24/73 (32%), Positives = 38/73 (52%), Gaps = 3/73 (4%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYS---KGILAEILEFVMGTGLIPADGE 234 HG LF + LG K ++VSD ++A+ N A S K ++AE++ + L+ G Sbjct: 73 HGPLFTIKLGAKKALVVSDWEMARECFTTNDVAVSARPKLLVAELMCYNNAMLLVAPYGP 132 Query: 235 VWRVRRRAIVPSL 273 WR R+ IV + Sbjct: 133 YWRELRKIIVTEI 145
>CP3AL_CALJA (O18993) Cytochrome P450 3A21 (EC 1.14.14.1) (CYPIIIA21) (P450| CM3A-10) Length = 503 Score = 39.7 bits (91), Expect = 0.006 Identities = 29/131 (22%), Positives = 62/131 (47%), Gaps = 1/131 (0%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHIL-RDNSKAYSKGILAEILEFVMGTGLIPADGEVW 240 +G ++ + G + + ++DP+I K +L ++ ++ + F+ I D E W Sbjct: 68 YGKMWGIYDGRQPVLAITDPNIIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAQDDE-W 126 Query: 241 RVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGK 420 + R + P+ + EM+ + + L L + A +G+ + M+ +F ++DVI Sbjct: 127 KRIRSLLSPTFTSGKLKEMVPIIAQYGEVLVRNLRREAEKGKPINMKDIFGAYSMDVITG 186 Query: 421 AVFNYDFDSLS 453 F + DSL+ Sbjct: 187 TSFGVNIDSLN 197
>CP2B3_RAT (P13107) Cytochrome P450 2B3 (EC 1.14.14.1) (CYPIIB3)| Length = 491 Score = 39.7 bits (91), Expect = 0.006 Identities = 34/133 (25%), Positives = 64/133 (48%), Gaps = 6/133 (4%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYS-KGILAEILEFVMGTGLIPADGEVW 240 HG +F + GP+ V++ + L D+++A+S +GI+A + + G+ + E W Sbjct: 62 HGDVFTVYFGPRPVVMLCGTQTIREALVDHAEAFSGRGIIAVLQPIMQEYGVSFVNEERW 121 Query: 241 RVRRRAIVPSLH-----QKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTL 405 ++ RR V ++ ++ V + I K L E+L +G ++ LF +T Sbjct: 122 KILRRLFVATMRDFGIGKQSVEDQIKEEAKC---LVEELKN--HQGVSLDPTFLFQCVTG 176 Query: 406 DVIGKAVFNYDFD 444 ++I VF FD Sbjct: 177 NIICSIVFGERFD 189
>CP3A3_HUMAN (P05184) Cytochrome P450 3A3 (EC 1.14.14.1) (CYPIIIA3) (HLp)| Length = 503 Score = 39.3 bits (90), Expect = 0.008 Identities = 30/123 (24%), Positives = 57/123 (46%), Gaps = 2/123 (1%) Frame = +1 Query: 91 GPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFV--MGTGLIPADGEVWRVRRRAIV 264 G + + ++DPD+ K +L + YS E V M + + A+ E W+ R + Sbjct: 76 GQQPVLAITDPDMIKLVLV--KECYSVFTNREPFGPVGFMKSAISIAEDEEWKRLRSLLS 133 Query: 265 PSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVFNYDFD 444 P+ + EM+ + + L L + G+ V ++ +F ++DVI + F + D Sbjct: 134 PTFTSGKLKEMVPIIAQYGDVLVRNLRRERETGKPVTLKDVFGAYSMDVITSSSFGVNVD 193 Query: 445 SLS 453 SL+ Sbjct: 194 SLN 196
>CP6B5_PAPGL (Q95036) Cytochrome P450 6B5 (EC 1.14.14.1) (CYPVIB5) (CYP6B5V1)| (Fragment) Length = 476 Score = 39.3 bits (90), Expect = 0.008 Identities = 25/114 (21%), Positives = 50/114 (43%), Gaps = 1/114 (0%) Frame = +1 Query: 106 VIVSDPDIAKHIL-RDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVRRRAIVPSLHQK 282 +++ D D+ KH++ +D +G+ E E +G + ADG+ WRV R+ P Sbjct: 80 LLLRDLDVIKHVMIKDFDLFNDRGV--EFSEEGLGLNIFHADGDRWRVLRQCFTPLFTSG 137 Query: 283 FVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVFNYDFD 444 + M+ L + + ++K + ++ L + T+ I F + D Sbjct: 138 KLKNMLNLMSDRGDKFIKMVEKICDKEPEQQIIPLVRKFTMASITTCAFGMELD 191
>CP3A5_HUMAN (P20815) Cytochrome P450 3A5 (EC 1.14.14.1) (CYPIIIA5) (P450-PCN3)| (HLp2) Length = 502 Score = 39.3 bits (90), Expect = 0.008 Identities = 31/132 (23%), Positives = 60/132 (45%), Gaps = 2/132 (1%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFV--MGTGLIPADGEV 237 +G ++ G + ++DPD+ + +L + YS L V M + + A+ E Sbjct: 68 YGKMWGTYEGQLPVLAITDPDVIRTVLV--KECYSVFTNRRSLGPVGFMKSAISLAEDEE 125 Query: 238 WRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIG 417 W+ R + P+ + EM + + L L + A +G+ V ++ +F ++DVI Sbjct: 126 WKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDVIT 185 Query: 418 KAVFNYDFDSLS 453 F + DSL+ Sbjct: 186 GTSFGVNIDSLN 197
>CP131_DROME (Q9VFJ0) Probable cytochrome P450 313a1 (EC 1.14.-.-)| (CYPCCCXIIIA1) Length = 492 Score = 38.9 bits (89), Expect = 0.010 Identities = 23/94 (24%), Positives = 36/94 (38%) Frame = +1 Query: 88 LGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVRRRAIVP 267 +GP F++ DP + + I + + MG GL+ W RR+ P Sbjct: 73 MGPVPFIVTRDPKVVEDIFSSPDCHNKSQHIVNAITSCMGNGLLGKQDPHWLDRRKHFNP 132 Query: 268 SLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEI 369 S Q + +F + L LD +GEI Sbjct: 133 SFKQDLLLSFFHIFDAETKVLMNLLDTYVDKGEI 166
>CP6B4_PAPGL (Q27902) Cytochrome P450 6B4 (EC 1.14.14.1) (CYPVIB4)| (CYP6B4V1/CYP6B4V2) Length = 500 Score = 38.9 bits (89), Expect = 0.010 Identities = 25/114 (21%), Positives = 50/114 (43%), Gaps = 1/114 (0%) Frame = +1 Query: 106 VIVSDPDIAKHIL-RDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVRRRAIVPSLHQK 282 +++ D D+ KH++ +D +G+ E E +G + ADG+ WRV R+ P Sbjct: 80 LLLRDLDVIKHVMIKDFDLFNDRGV--EFSEEGLGLNIFHADGDRWRVLRQCFTPLFTSG 137 Query: 283 FVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVFNYDFD 444 + M+ L + + ++K + ++ L + T+ I F + D Sbjct: 138 KLKNMLNLMSDRGDKFIKMVEKFCDKEPEQQIIPLVRKFTMASITTCAFGMELD 191
>CP3A8_MACFA (P33268) Cytochrome P450 3A8 (EC 1.14.14.1) (CYPIIIA8) (P450-MKNF2)| (P-450-MK2) Length = 503 Score = 38.9 bits (89), Expect = 0.010 Identities = 30/125 (24%), Positives = 56/125 (44%), Gaps = 4/125 (3%) Frame = +1 Query: 91 GPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEF----VMGTGLIPADGEVWRVRRRA 258 G + + ++DP++ K +L + YS + F M + A+ E W+ R Sbjct: 77 GRQPVLAITDPNMIKTVLV--KECYS--VFTNRRPFGPVGFMKNAISIAEDEEWKRIRSL 132 Query: 259 IVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVFNYD 438 + P+ + EM+ + K L L + A G+ V ++ +F ++DVI F + Sbjct: 133 LSPTFTSGKLKEMVPIIAKYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVN 192 Query: 439 FDSLS 453 DSL+ Sbjct: 193 IDSLN 197
>CP2F3_CAPHI (O18809) Cytochrome P450 2F3 (EC 1.14.14.1) (CYPIIF3)| Length = 491 Score = 38.9 bits (89), Expect = 0.010 Identities = 33/162 (20%), Positives = 68/162 (41%), Gaps = 10/162 (6%) Frame = +1 Query: 67 GGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYS-KGILAEILEFVMGTGLIPADGEVWR 243 G ++ + LGP+ V++S K L D ++ +S +G F G G+ ++G+ W+ Sbjct: 63 GAVYTVYLGPRRVVVLSGYQAVKEALVDQAEEFSGRGDYPAFFNFTKGNGIAFSNGDRWK 122 Query: 244 VRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKL---------DKAAAEGEIVEMESLFSR 396 R K+ +++ FG + E++ + +G+ + + SR Sbjct: 123 ALR---------KYSLQILRNFGMGKRTIEERILEEGHFLLEELRKTQGKPFDPTFVVSR 173 Query: 397 LTLDVIGKAVFNYDFDSLSYDNGMVEAVYVTLREAEMRSTSP 522 ++I +F FD YD+ + + + E +SP Sbjct: 174 SVSNIICSVIFGSRFD---YDDDRLLTIIHLINENFQIMSSP 212
>CP3A2_RAT (P05183) Cytochrome P450 3A2 (EC 1.14.14.1) (CYPIIIA2) (P450-PCN2)| (P450/6-beta-A) (Testosterone 6-beta-hydroxylase) Length = 504 Score = 38.5 bits (88), Expect = 0.013 Identities = 23/85 (27%), Positives = 40/85 (47%) Frame = +1 Query: 199 VMGTGLIPADGEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEM 378 +MG + A E W+ R + P+ + EM + + L + L + A G+ V M Sbjct: 113 IMGKAVSVAKDEEWKRYRALLSPTFTSGRLKEMFPIIEQYGDILVKYLKQEAETGKPVTM 172 Query: 379 ESLFSRLTLDVIGKAVFNYDFDSLS 453 + +F ++DVI F + DSL+ Sbjct: 173 KKVFGAYSMDVITSTSFGVNVDSLN 197
>CP3A1_RAT (P04800) Cytochrome P450 3A1 (EC 1.14.14.1) (CYPIIIA1) (P450-PCN1)| Length = 504 Score = 38.5 bits (88), Expect = 0.013 Identities = 23/85 (27%), Positives = 40/85 (47%) Frame = +1 Query: 199 VMGTGLIPADGEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEM 378 +MG + A E W+ R + P+ + EM + + L + L + A G+ V M Sbjct: 113 IMGKAVSVAKDEEWKRYRALLSPTFTSGRLKEMFPIIEQYGDILVKYLKQEAETGKPVTM 172 Query: 379 ESLFSRLTLDVIGKAVFNYDFDSLS 453 + +F ++DVI F + DSL+ Sbjct: 173 KKVFGAYSMDVITSTSFGVNVDSLN 197
>CPXB_BACME (P14779) Bifunctional P-450:NADPH-P450 reductase (Cytochrome| P450(BM-3)) (P450BM-3) [Includes: Cytochrome P450 102 (EC 1.14.14.1); NADPH--cytochrome P450 reductase (EC 1.6.2.4)] Length = 1048 Score = 38.5 bits (88), Expect = 0.013 Identities = 29/99 (29%), Positives = 50/99 (50%), Gaps = 5/99 (5%) Frame = +1 Query: 178 LAEILEFVM---GTGLIPA--DGEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKL 342 L++ L+FV G GL + + W+ ++PS Q+ + + + +L +K Sbjct: 71 LSQALKFVRDFAGDGLFTSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKW 130 Query: 343 DKAAAEGEIVEMESLFSRLTLDVIGKAVFNYDFDSLSYD 459 ++ A+ E +E+ +RLTLD IG FNY F+S D Sbjct: 131 ERLNAD-EHIEVPEDMTRLTLDTIGLCGFNYRFNSFYRD 168
>CP52C_CANMA (P16496) Cytochrome P450 52A3 (EC 1.14.14.-) (CYPLIIA3)| (Alkane-inducible P450-ALK1-A) (P450-CM1) (CYP52A3-A) (Cytochrome P-450ALK) Length = 522 Score = 38.5 bits (88), Expect = 0.013 Identities = 32/129 (24%), Positives = 54/129 (41%), Gaps = 6/129 (4%) Frame = +1 Query: 91 GPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVRRRAIVPS 270 G V DP+ K +L ++ G + ++G G+ DGE W++ R + P Sbjct: 95 GVLKIVFTVDPENIKAVLATQFNDFALGARHAHFDPLLGDGIFTLDGEGWKLSRAMLRPQ 154 Query: 271 L------HQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVFN 432 H K + + + K KL+K G+ +++ LF R T+D + +F Sbjct: 155 FAREQIAHVKALEPHVQILAKQI-----KLNK----GKTFDLQELFFRFTVDTATEFLFG 205 Query: 433 YDFDSLSYD 459 SL YD Sbjct: 206 ESVHSL-YD 213
>CP6B3_PAPPO (Q27756) Cytochrome P450 6B3 (EC 1.14.14.1) (CYPVIB4)| (CYP6B3V1/CYP6B3V2) Length = 498 Score = 38.1 bits (87), Expect = 0.017 Identities = 32/148 (21%), Positives = 57/148 (38%), Gaps = 3/148 (2%) Frame = +1 Query: 10 RWRPGXAIFLPLYDHFLTHG--GLFRLNLGPKSFVIVSDPDIAKHI-LRDNSKAYSKGIL 180 R +P ++ +YD F G++R+ V++ D DI KH+ +D +G+ Sbjct: 49 RRKPQVMVYKSIYDEFPNEKVVGIYRMTTPS---VLLRDLDIIKHVPTKDFEPFADRGV- 104 Query: 181 AEILEFVMGTGLIPADGEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAE 360 E +G + ADG+ WR R P + M+ L + + D+ + Sbjct: 105 -EFSLDGLGANIFHADGDRWRSLRNRFTPLFTSGKLKTMLPLMSQVGDKFINTSDEVSQT 163 Query: 361 GEIVEMESLFSRLTLDVIGKAVFNYDFD 444 + L T+ I F + D Sbjct: 164 KSEQSIHDLVQIFTITNIAACAFGLNLD 191
>CP9E2_BLAGE (Q964T2) Cytochrome P450 9e2 (EC 1.14.-.-) (CYPIXE2)| Length = 533 Score = 38.1 bits (87), Expect = 0.017 Identities = 35/146 (23%), Positives = 64/146 (43%), Gaps = 17/146 (11%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAY--SKGILAEILEFVMGTGLIPADGEV 237 +GG+F + P +++ DP++ K + + + + + ++E E + G L G Sbjct: 75 YGGMFEF-MNP--VLVLRDPELIKMVTVKDFEYFLDHRAPISEEAEPMFGKNLFNLRGHR 131 Query: 238 WRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLD-------------KAAAEGEI--V 372 W+ R + P+ + M L + +L E L K EG++ V Sbjct: 132 WKEMRSTLSPAFTSSKMKNMFVLVSECGKQLGEFLMECSRDKNKKTEGCKIEREGDLLTV 191 Query: 373 EMESLFSRLTLDVIGKAVFNYDFDSL 450 E++ L++R T DVI + F DSL Sbjct: 192 ELKDLYTRYTNDVIATSAFGIGCDSL 217
>CP6K1_BLAGE (Q964R0) Cytochrome P450 6k1 (EC 1.14.-.-) (CYPVIK1)| Length = 524 Score = 37.7 bits (86), Expect = 0.023 Identities = 27/120 (22%), Positives = 54/120 (45%), Gaps = 1/120 (0%) Frame = +1 Query: 106 VIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGT-GLIPADGEVWRVRRRAIVPSLHQK 282 +++ DP+I KH+L + A+S + +G+ L +G W+ R + P+ Sbjct: 87 ILIKDPNIIKHVLVKDFNAFSDRHASAAESDTLGSQNLFTLNGAPWKYLRVKLSPTFTSG 146 Query: 283 FVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVFNYDFDSLSYDN 462 + +M L + +L + L K + +E++ ++ DVI F + +SL N Sbjct: 147 RMKKMYPLVESCAKQLQDYL-KENCNTKAIEVKETTAKYATDVISTCAFGIESNSLKDPN 205
>CP52T_CANMA (Q12585) Cytochrome P450 52D1 (EC 1.14.14.-) (CYPLIID1)| (Alkane-inducible P450-ALK4) Length = 505 Score = 37.7 bits (86), Expect = 0.023 Identities = 29/116 (25%), Positives = 53/116 (45%) Frame = +1 Query: 106 VIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVRRRAIVPSLHQKF 285 ++ DP K +L +S G+ E ++G G+ +DGE W+ R + P + Sbjct: 89 ILTRDPVNIKAMLAVQFDEFSLGLRYNQFEPLLGNGIFTSDGEPWKHSRIMLRPQFIKSQ 148 Query: 286 VTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVFNYDFDSLS 453 V+ + L + L +K + A ++++LF R TLD + +F SL+ Sbjct: 149 VSHVNRL--EPHFNLLQK-NITAQTDNYFDIQTLFFRFTLDTATEFLFGQSVHSLN 201
>CP52J_CANMA (Q12588) Cytochrome P450 52A10 (EC 1.14.14.-) (CYPLIIA10)| (Alkane-inducible P450-ALK7) Length = 519 Score = 37.7 bits (86), Expect = 0.023 Identities = 30/130 (23%), Positives = 54/130 (41%), Gaps = 6/130 (4%) Frame = +1 Query: 103 FVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVRRRAIVPSLHQK 282 F+ DP+ K +L Y+ G L ++G G+ DG W+ R + P + Sbjct: 96 FIATKDPENIKAMLATQFNEYTLGQRLNFLAPLLGKGIFTLDGNGWKHSRAMLRP----Q 151 Query: 283 FVTEMIGLFGKASGRL-CEKLDKAAAEGEIVEMESLFSRLTLD-----VIGKAVFNYDFD 444 F + IG K +G +++ LF R T+D + G++V + + Sbjct: 152 FSRDQIGHVKMLEPHFQLLKKHIIKNKGTFFDIQELFFRFTVDSATEFLFGESVSSLKDE 211 Query: 445 SLSYDNGMVE 474 S+ YD ++ Sbjct: 212 SIGYDQEEID 221
>CP341_MOUSE (Q9JMA7) Cytochrome P450 3A41 (EC 1.14.14.1)| Length = 504 Score = 37.4 bits (85), Expect = 0.030 Identities = 34/154 (22%), Positives = 68/154 (44%), Gaps = 4/154 (2%) Frame = +1 Query: 4 RGRWRPGXAIFLPLYDHFLTHGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILA 183 +G W+ + Y+ + GLF G +++DP++ K++L + +S + Sbjct: 55 KGLWK----FDMECYEKYGKTWGLFD---GQMPLFVITDPEMIKNVLV--KECFS--VFT 103 Query: 184 EILEF----VMGTGLIPADGEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKA 351 EF +M + + E W+ R + P+ + EM + + L + L + Sbjct: 104 NRREFGPVGIMSKAISISKDEEWKRYRALLSPTFTSGKLKEMFPVIEQYGDILVKYLMQE 163 Query: 352 AAEGEIVEMESLFSRLTLDVIGKAVFNYDFDSLS 453 A +G+ V M+ + ++DVI F + DSL+ Sbjct: 164 AEKGKPVTMKDVLGAYSIDVITSTSFGVNVDSLN 197
>CP3A7_HUMAN (P24462) Cytochrome P450 3A7 (EC 1.14.14.1) (CYPIIIA7) (P450-HFLA)| Length = 503 Score = 37.4 bits (85), Expect = 0.030 Identities = 29/118 (24%), Positives = 52/118 (44%), Gaps = 4/118 (3%) Frame = +1 Query: 112 VSDPDIAKHILRDNSKAYSKGILAEILEF----VMGTGLIPADGEVWRVRRRAIVPSLHQ 279 ++DPD+ K +L + YS + F M + A+ E W+ R + P+ Sbjct: 84 ITDPDMIKTVLV--KECYS--VFTNRRPFGPVGFMKNAISIAEDEEWKRIRSLLSPTFTS 139 Query: 280 KFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVFNYDFDSLS 453 + EM+ + + L L + A G+ V ++ +F ++DVI F DSL+ Sbjct: 140 GKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVITSTSFGVSIDSLN 197
>C71AK_ARATH (Q9T0K2) Cytochrome P450 71A20 (EC 1.14.-.-)| Length = 495 Score = 37.4 bits (85), Expect = 0.030 Identities = 36/169 (21%), Positives = 70/169 (41%), Gaps = 10/169 (5%) Frame = +1 Query: 58 LTHGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTG---LIPAD 228 L +G L L+ G +IVS D+A +++ + + ++++ ++ G Sbjct: 59 LRYGPLMLLHFGRTPVLIVSSADVAHDVMKTHDLVCANRPKTKVVDKILSGGRDVAFAPY 118 Query: 229 GEVWRVRRRAIVPS-LHQKFVTEMIGLFGKASGRLCEKLDKAAAEG--EIVEMESLFSRL 399 GE WR + + + L+ K V + + R+ EKL+KA+ V + + L Sbjct: 119 GEYWRQMKSICIQNLLNNKMVRSYEKIREEEIKRMIEKLEKASCSSSPSPVNLSQILMTL 178 Query: 400 TLDVIGKAVFNYDF----DSLSYDNGMVEAVYVTLREAEMRSTSPIPTW 534 T D+I + + D + +N +V L E + P +W Sbjct: 179 TNDIICRVALGRKYSGKKDGIDVEN-IVRTFAALLGEFPVGEYIPSLSW 226
>CYPD_BACSU (O08394) Probable bifunctional P-450:NADPH-P450 reductase 1| [Includes: Cytochrome P450 102 (EC 1.14.14.1); NADPH--cytochrome P450 reductase (EC 1.6.2.4)] Length = 1061 Score = 37.4 bits (85), Expect = 0.030 Identities = 36/147 (24%), Positives = 67/147 (45%), Gaps = 9/147 (6%) Frame = +1 Query: 67 GGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYS-KGILAEILEFVMGTGLIPA--DGEV 237 G +F+++ + ++VS ++ K + + S +G L ++ F G GL + Sbjct: 39 GPIFQIHTPAGTTIVVSGHELVKEVCDEERFDKSIEGALEKVRAF-SGDGLFTSWTHEPN 97 Query: 238 WRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIG 417 WR ++P+ Q+ + + + +L +K + E V++ +RLTLD IG Sbjct: 98 WRKAHNILMPTFSQRAMKDYHEKMVDIAVQLIQKWARLNPN-EAVDVPGDMTRLTLDTIG 156 Query: 418 KAVFNYDFDSL------SYDNGMVEAV 480 FNY F+S + N MV A+ Sbjct: 157 LCGFNYRFNSYYRETPHPFINSMVRAL 183
>C13AA_CAEEL (Q09653) Putative cytochrome P450 CYP13A10 (EC 1.14.-.-)| Length = 519 Score = 37.4 bits (85), Expect = 0.030 Identities = 33/152 (21%), Positives = 62/152 (40%), Gaps = 3/152 (1%) Frame = +1 Query: 34 FLPLYDHFLTHGGLFRLNLGPKSFVIVSDPDIAKHIL---RDNSKAYSKGILAEILEFVM 204 +L + D +G ++ G +IVSD DI + I DN + E Sbjct: 54 YLQIRDWTKLYGPIYGYTEGTIKTLIVSDIDIVRQIFVEQYDNFYGRKLNPIQGDPEKDE 113 Query: 205 GTGLIPADGEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMES 384 T L A G W+ R P+ + ++ ++ L +++ +EG+ ++M Sbjct: 114 RTNLFSAQGFRWKRLRAISSPTFSNNSLRKINVTVEDSAMELLRHIEEQTSEGQQIDMLQ 173 Query: 385 LFSRLTLDVIGKAVFNYDFDSLSYDNGMVEAV 480 + T+D IG+ DS + N +++ V Sbjct: 174 FYQEFTMDTIGRIAMG-QTDSQMFKNPLLKFV 204
>CP270_RAT (P19225) Cytochrome P450 2C70 (EC 1.14.14.1) (CYPIIC70) (P-450Md)| (P450 P49) Length = 489 Score = 37.0 bits (84), Expect = 0.039 Identities = 19/65 (29%), Positives = 37/65 (56%), Gaps = 1/65 (1%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFV-MGTGLIPADGEVW 240 +G +F + LG K V++ ++ K L D + +S + + +L V G G++ ++GE+W Sbjct: 61 YGPVFTMYLGMKPTVVLYGYEVLKEALIDRGEEFSDKMHSSMLSKVSQGLGIVFSNGEIW 120 Query: 241 RVRRR 255 + RR Sbjct: 121 KQTRR 125
>C6A13_DROME (Q9V4U9) Probable cytochrome P450 6a13 (EC 1.14.-.-) (CYPVIA13)| Length = 493 Score = 36.6 bits (83), Expect = 0.051 Identities = 35/120 (29%), Positives = 54/120 (45%), Gaps = 2/120 (1%) Frame = +1 Query: 97 KSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVRRRAIVPSLH 276 KS I+ I ++RD S +G+ + + + L+ DG WR R+ +L Sbjct: 78 KSLFIMDLELIRDIMIRDFSSFADRGLFHNVRDDPLTGNLLFLDGPEWRWLRQ----NLT 133 Query: 277 QKFVTEMIGLFGKASGRLCEKLDKAA--AEGEIVEMESLFSRLTLDVIGKAVFNYDFDSL 450 Q F + + + EKL +A GEI E + L +R T DVIG F + +SL Sbjct: 134 QVFTSGKMKFMFPNMVEVGEKLTQACRLQVGEI-EAKDLCARFTTDVIGSCAFGLECNSL 192
>CP318_DROME (Q9VYQ5) Probable cytochrome P450 318a1 (EC 1.14.-.-)| (CYPCCCXVIIIA1) Length = 536 Score = 36.6 bits (83), Expect = 0.051 Identities = 24/105 (22%), Positives = 44/105 (41%), Gaps = 4/105 (3%) Frame = +1 Query: 196 FVMGTGLIPADGEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLD-KAAAEGEIV 372 F + GL+ A G+ W++RR+ + P+ V +F ++ E+ + G+ V Sbjct: 109 FFVRRGLLHARGQKWKLRRKQLNPAFSHNIVASFFDVFNSVGNQMVEQFQTQTNLHGQAV 168 Query: 373 EM---ESLFSRLTLDVIGKAVFNYDFDSLSYDNGMVEAVYVTLRE 498 + E L SR L+V + + D+ + Y L E Sbjct: 169 KFTAAEDLLSRAVLEVSCLTIMGTPTNFTQLDDAHIAHSYKRLLE 213
>CP391_DROME (Q9VQD2) Probable cytochrome P450 309a1 (EC 1.14.-.-) (CYPCCCIXA1)| Length = 529 Score = 36.6 bits (83), Expect = 0.051 Identities = 30/123 (24%), Positives = 56/123 (45%), Gaps = 7/123 (5%) Frame = +1 Query: 106 VIVSDPDIAKHILRDNSKAYSKGILAEIL------EFVMGTGLIPADGEVWRVRRRAIVP 267 ++V DP +A IL D + I + + ++V G+ A G+ W+ R V Sbjct: 109 LLVLDPALAHEILVDKFSHFRDTITSSFVGHNPDDKYVAGSPFFSA-GDKWKRLRSENVG 167 Query: 268 SLHQKFVTEMIGLFGKASGRLCEKLDKAAAE-GEIVEMESLFSRLTLDVIGKAVFNYDFD 444 L + ++ ++ +L E +++A E G+I+E L R T + + ++ D Sbjct: 168 GLTPSRLKMAYSIWEQSGRKLVEYIERARREQGDIIETRDLAYRFTANAMADFIWGIDAG 227 Query: 445 SLS 453 SLS Sbjct: 228 SLS 230
>C4D10_DROMT (O18596) Cytochrome P450 4d10 (EC 1.14.-.-) (CYPIVD10)| Length = 513 Score = 36.6 bits (83), Expect = 0.051 Identities = 27/117 (23%), Positives = 51/117 (43%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWR 243 + G F+L +G +++ P + +L +S+ K + L + GL+ + G W Sbjct: 77 YDGTFKLKMGSNFSLMMFQPRDIEVVL-GSSQLLDKAVEYSFLRGWLNDGLLLSGGRKWH 135 Query: 244 VRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVI 414 RR+ I P+ H + + +F + + L K + G ++ TLDVI Sbjct: 136 RRRKIITPAFHFRILESYDEIFDRQTRLLIHKWQQTL--GHSFDLGHDVHLFTLDVI 190
>CP3AA_MESAU (Q64148) Cytochrome P450 3A10 (EC 1.14.13.94) (CYPIIIA10)| (Lithocholate 6-beta-hydroxylase) (6 beta-hydroxylase) Length = 503 Score = 36.2 bits (82), Expect = 0.066 Identities = 30/132 (22%), Positives = 57/132 (43%), Gaps = 2/132 (1%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFV--MGTGLIPADGEV 237 +G ++ G + ++DP+I K +L + YS V M + + E Sbjct: 68 YGKIWGFYDGRVPVLAIADPEIIKTVLV--KECYSNFTNRRSFGPVGFMKKSITISKDEE 125 Query: 238 WRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIG 417 W+ R + P+ + EM + G+ L + L + +G+ V M+ + ++DVI Sbjct: 126 WKRLRTLLSPAFTSGKLKEMFPIIGQYGDTLVKNLRREEEKGKPVNMKEILGAYSMDVIT 185 Query: 418 KAVFNYDFDSLS 453 F + DSL+ Sbjct: 186 GTSFGVNVDSLN 197
>CP2CU_RABIT (Q29510) Cytochrome P450 2C30 (EC 1.14.14.1) (CYPIIC30)| Length = 489 Score = 36.2 bits (82), Expect = 0.066 Identities = 17/65 (26%), Positives = 33/65 (50%), Gaps = 1/65 (1%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILE-FVMGTGLIPADGEVW 240 +G +F + G K V++ + K L D+ + +S + + + + G GL + GE+W Sbjct: 61 YGPVFTVYFGTKPSVVLHGYEAVKEALVDHGEEFSGRVTVPVFDRYAQGAGLFASQGELW 120 Query: 241 RVRRR 255 + RR Sbjct: 121 KETRR 125
>CP52K_CANMA (Q12589) Cytochrome P450 52A11 (EC 1.14.14.-) (CYPLIIA11)| (Alkane-inducible P450-ALK8) Length = 519 Score = 36.2 bits (82), Expect = 0.066 Identities = 29/129 (22%), Positives = 57/129 (44%), Gaps = 5/129 (3%) Frame = +1 Query: 103 FVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVRRRAIVPSLHQK 282 F+ DP+ K +L ++ G ++G G+ DGE W+ R + P + Sbjct: 96 FIATKDPENIKAMLATQFNDFTLGQRLSYFAPLLGKGIFTLDGEGWKHSRAMLRPQFSRD 155 Query: 283 FVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLD-----VIGKAVFNYDFDS 447 V + L + +L +K +G +++ LF R T+D + G++V + +S Sbjct: 156 QVGHVKML--EPHFQLLKK-HIIKNKGSFFDIQELFFRFTVDSATEFLFGESVSSLKDES 212 Query: 448 LSYDNGMVE 474 + YD ++ Sbjct: 213 IGYDQEEID 221
>CP3AV_MESAU (O70537) Cytochrome P450 3A31 (EC 1.14.14.1) (CYPIIIA31) (P450| SH3A-1) Length = 501 Score = 35.8 bits (81), Expect = 0.087 Identities = 31/134 (23%), Positives = 59/134 (44%), Gaps = 4/134 (2%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEF----VMGTGLIPADG 231 +G ++ L G + V+D ++ K++L + YS I +F +M + + Sbjct: 68 YGKIWGLFEGQRPLFTVTDTEMIKNVLV--KECYS--IFTNRRDFGPVGIMSKAVSISKD 123 Query: 232 EVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDV 411 E W+ R + P+ + EM + + L + L + A +G V + +F ++DV Sbjct: 124 EEWKRIRALLSPTFTSGKLKEMFPIIEQYGDILVKFLRREAEKGNPVTTKEVFGAYSMDV 183 Query: 412 IGKAVFNYDFDSLS 453 I F DSL+ Sbjct: 184 ITSTAFGVSVDSLN 197
>CP4G1_DROME (Q9V3S0) Cytochrome P450 4g1 (EC 1.14.-.-) (CYPIVG1)| Length = 556 Score = 35.8 bits (81), Expect = 0.087 Identities = 18/70 (25%), Positives = 35/70 (50%) Frame = +1 Query: 205 GTGLIPADGEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMES 384 G GL+ ++G WR R+ I P+ HQ + + F S + ++ A G+ ++ Sbjct: 137 GDGLLISNGHHWRHHRKMIAPTFHQSILKSFVPTFVDHSKAVVARMGLEA--GKSFDVHD 194 Query: 385 LFSRLTLDVI 414 S+ T+D++ Sbjct: 195 YMSQTTVDIL 204
>CP3AG_MOUSE (Q64481) Cytochrome P450 3A16 (EC 1.14.14.1) (CYPIIIA16)| Length = 504 Score = 35.4 bits (80), Expect = 0.11 Identities = 31/150 (20%), Positives = 62/150 (41%) Frame = +1 Query: 4 RGRWRPGXAIFLPLYDHFLTHGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILA 183 +G W+ + Y+ + GLF G +++DP+ K++L + Sbjct: 55 KGLWK----FDMECYEKYGKTWGLFD---GQIPLFVITDPETIKNVLVKECFSVFTNRQD 107 Query: 184 EILEFVMGTGLIPADGEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEG 363 +M + A E W+ R + P+ + EM + + L + L + A +G Sbjct: 108 FFPVGIMSKSISLAKDEEWKRYRALLSPTFTSGNLKEMFPVIEQYGDILVKYLRQEAEKG 167 Query: 364 EIVEMESLFSRLTLDVIGKAVFNYDFDSLS 453 + V ++ + ++DVI F + DSL+ Sbjct: 168 KPVAVKDVLGAYSMDVIISTTFGVNIDSLN 197
>CP2J5_MOUSE (O54749) Cytochrome P450 2J5 (EC 1.14.14.1) (CYPIIJ5) (Arachidonic| acid epoxygenase) Length = 501 Score = 35.4 bits (80), Expect = 0.11 Identities = 18/71 (25%), Positives = 36/71 (50%), Gaps = 1/71 (1%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMG-TGLIPADGEVW 240 +G +F L LG V+VS + K + + + + + E + G GL+ ++G+ W Sbjct: 75 YGNVFSLELGQSPVVVVSGLPLIKEMFTHLDQNFVNRFMTPVRERITGKNGLVVSNGQTW 134 Query: 241 RVRRRAIVPSL 273 + +RR + +L Sbjct: 135 KEQRRLALMAL 145
>C13A2_CAEEL (Q27518) Putative cytochrome P450 CYP13A2 (EC 1.14.-.-)| Length = 515 Score = 35.4 bits (80), Expect = 0.11 Identities = 32/142 (22%), Positives = 57/142 (40%), Gaps = 3/142 (2%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILR---DNSKAYSKGILAEILEFVMGTGLIPADGE 234 +G ++ G + ++V+DP + I DN + E L+ A G Sbjct: 66 YGKVYGYTDGTQRTLVVADPAMVHEIFVKQFDNFYGRKLNPIQGNPEKEQRVHLLAAQGY 125 Query: 235 VWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVI 414 W+ R S + +M ++ L ++K A GE ++M + T+DVI Sbjct: 126 RWKRLRTISSQSFSNASLKKMKRTVEDSALELLRHIEKQTAGGEQIDMLRFYQEYTMDVI 185 Query: 415 GKAVFNYDFDSLSYDNGMVEAV 480 G+ DS+ + N +V V Sbjct: 186 GRFAMG-QTDSMMFKNPIVNVV 206
>CP52L_DEBHA (Q9Y757) Cytochrome P450 52A12 (EC 1.14.14.-) (Alkane hydroxylase| 1) (Alkane-inducible p450alk 1) (DH-ALK2) Length = 519 Score = 35.0 bits (79), Expect = 0.15 Identities = 29/131 (22%), Positives = 52/131 (39%), Gaps = 6/131 (4%) Frame = +1 Query: 76 FRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVRRR 255 F + + +P+ K +L ++ G + ++G G+ DG W+ R Sbjct: 86 FSFRIAGTPVISTKNPENIKALLATQFSDFALGTRHAQFKPLLGDGIFTLDGSGWKHSRA 145 Query: 256 AIVPSL------HQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIG 417 + P H K + I + K R A+G +++SLF RLT+D Sbjct: 146 MLRPQFAREQVAHVKSLEPHIQMLAKHVRR---------AKGGAFDVQSLFFRLTVDSAT 196 Query: 418 KAVFNYDFDSL 450 + +F +SL Sbjct: 197 EFLFGESVESL 207
>CP2CK_MACFA (P33262) Cytochrome P450 2C20 (EC 1.14.14.1) (CYPIIC20)| (P450-MKMP13) (P450-MK1) Length = 490 Score = 34.7 bits (78), Expect = 0.19 Identities = 20/71 (28%), Positives = 37/71 (52%), Gaps = 1/71 (1%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYS-KGILAEILEFVMGTGLIPADGEVW 240 +G +F + G V++ + K L DN++ +S +GIL G G+I ++G+ W Sbjct: 61 YGPVFTVYFGMNPVVVLHGYETVKEALIDNAEEFSGRGILPISERITNGLGIISSNGKRW 120 Query: 241 RVRRRAIVPSL 273 + RR + +L Sbjct: 121 KETRRFSLTTL 131
>CP308_DROME (Q9VWR2) Probable cytochrome P450 308a1 (EC 1.14.-.-)| (CYPCCCVIIIA1) Length = 490 Score = 34.3 bits (77), Expect = 0.25 Identities = 35/137 (25%), Positives = 58/137 (42%), Gaps = 10/137 (7%) Frame = +1 Query: 58 LTHGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKA----------YSKGILAEILEFVMG 207 L + G +RL P ++V D ++ + IL + A + + +LA F+ Sbjct: 65 LKYVGFYRLFNEPA--ILVRDQELLRQILVGRNFADCADNAVYVDHQRDVLASHNPFI-- 120 Query: 208 TGLIPADGEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESL 387 A+G+ WRV R +VP V + + +A C+ L G E + L Sbjct: 121 -----ANGDRWRVLRADLVPLFTPSRVRQTLPHVARA----CQLLRDQVPLGRF-EAKDL 170 Query: 388 FSRLTLDVIGKAVFNYD 438 +R TL V+ A+F D Sbjct: 171 ATRYTLQVVASAIFGLD 187
>CP17A_ORYLA (P70085) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 517 Score = 34.3 bits (77), Expect = 0.25 Identities = 35/161 (21%), Positives = 61/161 (37%), Gaps = 22/161 (13%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGE--- 234 +G + L +G +IV+ A+ +L + ++ + + G A G+ Sbjct: 65 YGQTYSLKMGSHQVIIVNHHAHAREVLLKRGRTFAGRPRTVTTDVLTRDGKDIAFGDYSA 124 Query: 235 VWRVRRRAIVPSLHQKFVTEMIGLFGKASGRL-----------CEKLDKAAAEGEIVEME 381 WR H+K V + +FG+ S L C L +AAA G +++ Sbjct: 125 TWR---------FHRKIVHGALCMFGEGSASLQRIICTEAQSLCSTLSEAAATGLALDLS 175 Query: 382 SLFSRLTLDVIGKAVFNYDFD--------SLSYDNGMVEAV 480 +R +VI FN + L Y G+V+ V Sbjct: 176 PELTRAVTNVICSLCFNSSYSRGDPEFEAMLRYSQGIVDTV 216
>C76C1_ARATH (O64636) Cytochrome P450 76C1 (EC 1.14.-.-)| Length = 512 Score = 34.3 bits (77), Expect = 0.25 Identities = 28/134 (20%), Positives = 58/134 (43%), Gaps = 5/134 (3%) Frame = +1 Query: 61 THGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYS----KGILAEILEFVMGTGLIPAD 228 T+G + L LG + V+++ P+ A+ +LR + + S + I +P+ Sbjct: 68 TYGPVMSLKLGSLNTVVIASPEAAREVLRTHDQILSARSPTNAVRSINHQDASLVWLPSS 127 Query: 229 GEVWR-VRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTL 405 WR +RR ++ L + + L L + +++ E V++ + TL Sbjct: 128 SARWRLLRRLSVTQLLSPQRIEATKALRMNKVKELVSFISESSDREESVDISRVAFITTL 187 Query: 406 DVIGKAVFNYDFDS 447 ++I +F+ D S Sbjct: 188 NIISNILFSVDLGS 201
>C99A1_SORBI (O48957) Cytochrome P450 CYP99A1 (EC 1.14.-.-) (Fragment)| Length = 519 Score = 34.3 bits (77), Expect = 0.25 Identities = 23/81 (28%), Positives = 39/81 (48%), Gaps = 4/81 (4%) Frame = +1 Query: 43 LYDHFLTHGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKG---ILAEILEF-VMGT 210 L D + HG + L LG V++S P A+ +LRD ++ ++A+I+ + M Sbjct: 52 LRDLAMKHGPVMYLRLGQVDAVVISSPAAAQEVLRDKDTTFASRPSLLVADIILYGSMDM 111 Query: 211 GLIPADGEVWRVRRRAIVPSL 273 P G WR+ R+ + L Sbjct: 112 SFAPYGGN-WRMLRKLCMSEL 131
>CP18A_DROME (Q95078) Cytochrome P450 18a1 (EC 1.14.-.-) (CYPXVIIIA1)| Length = 538 Score = 33.9 bits (76), Expect = 0.33 Identities = 28/122 (22%), Positives = 59/122 (48%), Gaps = 5/122 (4%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWR 243 +G LF LG + V++SD + + R + ++ ++ + G G+I + G++W+ Sbjct: 84 YGSLFSTRLGSQLTVVMSDYKMIRECFR--REEFTGRPDTPFMQTLNGYGIINSTGKLWK 141 Query: 244 VRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDK-----AAAEGEIVEMESLFSRLTLD 408 +RR + L Q +T M + R+ ++ + A++G+ V+M + S + Sbjct: 142 DQRRFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSN 201 Query: 409 VI 414 VI Sbjct: 202 VI 203
>CP3AB_MOUSE (Q64459) Cytochrome P450 3A11 (EC 1.14.14.1) (CYPIIIA11)| (P-450IIIAM1) (P-450UT) Length = 504 Score = 33.5 bits (75), Expect = 0.43 Identities = 29/134 (21%), Positives = 60/134 (44%), Gaps = 4/134 (2%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEF----VMGTGLIPADG 231 +G + L G + V+DP+ K++L + +S + +F +M + + Sbjct: 68 YGKTWGLFDGQTPLLAVTDPETIKNVLV--KECFS--VFTNRRDFGPVGIMSKAISISKD 123 Query: 232 EVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDV 411 + W+ R + P+ + EM + + L + L + A +G+ V M+ + ++DV Sbjct: 124 DEWKRYRALLSPTFTSGKLKEMFPVIEQYGDILVKYLRQKAKKGKPVTMKDVLGAYSMDV 183 Query: 412 IGKAVFNYDFDSLS 453 I F + DSL+ Sbjct: 184 ITSTSFGVNVDSLN 197
>CP2CN_RAT (P24470) Cytochrome P450 2C23 (EC 1.14.14.1) (CYPIIC23)| (Arachidonic acid epoxygenase) Length = 494 Score = 33.5 bits (75), Expect = 0.43 Identities = 20/65 (30%), Positives = 34/65 (52%), Gaps = 1/65 (1%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKH-ILRDNSKAYSKGILAEILEFVMGTGLIPADGEVW 240 +G ++ L G V++ D+ K +L+ + +G L I + G GLI ++GE W Sbjct: 65 YGPVYTLYFGTSPTVVLHGYDVVKEALLQQGDEFLGRGPLPIIEDTHKGYGLIFSNGERW 124 Query: 241 RVRRR 255 +V RR Sbjct: 125 KVMRR 129
>CP2J1_RABIT (P52786) Cytochrome P450 2J1 (EC 1.14.14.1) (CYPIIJ1) (P-450IB)| Length = 500 Score = 33.5 bits (75), Expect = 0.43 Identities = 24/80 (30%), Positives = 39/80 (48%), Gaps = 1/80 (1%) Frame = +1 Query: 37 LPLYDHFLTHGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILE-FVMGTG 213 L L +G LF L+L KS VIV+ + K +L + + + I E G Sbjct: 65 LQLQQFVKKYGNLFCLDLAGKSIVIVTGLPLIKEVLVHMDQNFINRPVPPIRERSFKKNG 124 Query: 214 LIPADGEVWRVRRRAIVPSL 273 LI + G++W+ +RR + +L Sbjct: 125 LIMSSGQLWKEQRRFALMTL 144
>CP2J6_MOUSE (O54750) Cytochrome P450 2J6 (EC 1.14.14.1) (CYPIIJ6) (Arachidonic| acid epoxygenase) Length = 501 Score = 33.1 bits (74), Expect = 0.56 Identities = 24/99 (24%), Positives = 46/99 (46%), Gaps = 1/99 (1%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMG-TGLIPADGEVW 240 +G +F LNLG + V+++ + K L + L+ + E + GLI + G++W Sbjct: 75 YGNIFSLNLGDITSVVITGLPLIKEALTQMEQNIMNRPLSVMQERISNKNGLIFSSGQIW 134 Query: 241 RVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAA 357 + +RR + +L FG L E++ + A+ Sbjct: 135 KEQRRFALMTLRN---------FGLGKKSLEERMQEEAS 164
>CP17A_SQUAC (Q92113) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 33.1 bits (74), Expect = 0.56 Identities = 29/117 (24%), Positives = 51/117 (43%), Gaps = 4/117 (3%) Frame = +1 Query: 61 THGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTG----LIPAD 228 T+G LF L +GP V++++ AK +L K ++ G + + ++ G Sbjct: 64 TYGNLFSLMMGPHYAVVINNHQHAKEVLLKKGKIFA-GRPSMVTTDLLSRGGKDIAFGKY 122 Query: 229 GEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRL 399 G W+ R+ ++ +LH LFG S + + + + E M S F RL Sbjct: 123 GPAWKFHRKLVLSALH---------LFGDGSAGIEKMICQ-----EATSMCSTFERL 165
>C71AJ_ARATH (Q9T0K0) Cytochrome P450 71A19 (EC 1.14.-.-)| Length = 490 Score = 32.7 bits (73), Expect = 0.73 Identities = 31/136 (22%), Positives = 57/136 (41%), Gaps = 6/136 (4%) Frame = +1 Query: 58 LTHGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTG---LIPAD 228 L +G L L+ G +IVS D+A IL+ + ++++ ++ G Sbjct: 62 LRYGPLMLLHFGRTPVLIVSSADVAHDILKTYDVICANRPKTKVIDKILRGGRDVAFAPY 121 Query: 229 GEVWRVRRRAIVPS-LHQKFVTEMIGLFGKASGRLCEKLDKAA--AEGEIVEMESLFSRL 399 GE W+ + + + L K V + + EK++ A+ + V + LF L Sbjct: 122 GEYWKQMKSICIQNLLSNKMVRSYKKIREDEIKLMIEKVENASSCSPPSPVNLSQLFMTL 181 Query: 400 TLDVIGKAVFNYDFDS 447 T D+I +A + S Sbjct: 182 TNDIICRAALGRKYSS 197
>C13A6_CAEEL (Q27515) Putative cytochrome P450 CYP13A6 (EC 1.14.-.-)| Length = 518 Score = 32.7 bits (73), Expect = 0.73 Identities = 24/132 (18%), Positives = 53/132 (40%), Gaps = 3/132 (2%) Frame = +1 Query: 34 FLPLYDHFLTHGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEIL---EFVM 204 FL D +G ++ GP+ +I+S+P++ I + + L I+ E Sbjct: 52 FLKYRDWTKQYGPVYGFTEGPQQTMIISEPEMVNEIFKKQFDNFYGRKLRPIIGDPEKDK 111 Query: 205 GTGLIPADGEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMES 384 + G+ W+ R PS + ++ + + +++ + E ++M Sbjct: 112 RVNIFSTQGKRWKRLRTLSSPSFSNNSLRKVRNSVQECGTEILWNIEQKVRKNEDIDMLI 171 Query: 385 LFSRLTLDVIGK 420 ++ TL VI + Sbjct: 172 VYQEYTLGVISR 183
>CP4P2_DROME (Q9V557) Probable cytochrome P450 4p2 (EC 1.14.-.-) (CYPIVP2)| Length = 520 Score = 32.7 bits (73), Expect = 0.73 Identities = 25/123 (20%), Positives = 54/123 (43%) Frame = +1 Query: 85 NLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVRRRAIV 264 ++G +F ++ D A +IL ++ +KG++ L + TG++ A + W RR + Sbjct: 90 SMGFSNFNVI-DAHNAANIL-NHPNLITKGVIYNFLHPFLRTGVLTATEKKWHTRRSMLT 147 Query: 265 PSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVFNYDFD 444 + H + + +F S + + +V ++ SR TL+ I + D Sbjct: 148 RTFHLDILNQFQEIFIAESLKFVSQFQ--GQNEVVVSLKDRISRFTLNSICETAMGIKLD 205 Query: 445 SLS 453 ++ Sbjct: 206 EMA 208
>C11B1_MESAU (P97720) Cytochrome P450 11B1, mitochondrial precursor (EC| 1.14.15.4) (CYPXIB1) (P450C11) (Steroid 11-beta-hydroxylase) Length = 499 Score = 32.7 bits (73), Expect = 0.73 Identities = 42/193 (21%), Positives = 77/193 (39%), Gaps = 18/193 (9%) Frame = +1 Query: 31 IFLPLYDHFLTHGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGIL----AEILEF 198 + L +++ F G +FR ++G V V P++A+ + + +S S+ +L A Sbjct: 64 LHLEMHEAFRELGPIFRYSMGRTQVVYVMLPEVAEKVFQADSTQPSRTLLEPWVAHREHR 123 Query: 199 VMGTGLIPADGEVWRVRRRAIVPSL-----HQKFVTEMIGLFGKASGRLCEKLDKAAAEG 363 + G+ +G WR R I P + QKFV M+ + + +K A A G Sbjct: 124 GLSRGVFLLNGPEWRFNRLRINPHMLSPKAVQKFV-PMVDMVARDFLEFLKKKVLANAHG 182 Query: 364 EI-VEMESLFSRLTLDVIGKAVFNYDFDSLSYDNGMVEAVYVTLREAEMRST-------S 519 + + S T++ +F L D +V + M++T S Sbjct: 183 SLSMNFYSSMFNYTIEASHFVLFGERLGLLGDDLNSGSLKFVNALNSIMKTTPQLMLLPS 242 Query: 520 PIPTW-KIPIWKD 555 + W +WK+ Sbjct: 243 GLTRWISTRVWKE 255
>CP138_MYCTU (P63717) Putative cytochrome P450 138 (EC 1.14.-.-)| Length = 441 Score = 32.3 bits (72), Expect = 0.96 Identities = 28/109 (25%), Positives = 49/109 (44%), Gaps = 1/109 (0%) Frame = +1 Query: 106 VIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPA-DGEVWRVRRRAIVPSLHQK 282 V+V+DP +A+ + S G + L + G+G + A DG+ R RRR + P H K Sbjct: 61 VVVADPQLARQVF--TSSPEELGNIQPNLSRMFGSGSVFALDGDDHRRRRRLLAPPFHGK 118 Query: 283 FVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVF 429 + + + + R + A + M +TL+ I +A+F Sbjct: 119 SMKNYETIIEEETLRETANWPQGQAFATLPSM----MHITLNAILRAIF 163
>CP138_MYCBO (P63718) Putative cytochrome P450 138 (EC 1.14.-.-)| Length = 441 Score = 32.3 bits (72), Expect = 0.96 Identities = 28/109 (25%), Positives = 49/109 (44%), Gaps = 1/109 (0%) Frame = +1 Query: 106 VIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPA-DGEVWRVRRRAIVPSLHQK 282 V+V+DP +A+ + S G + L + G+G + A DG+ R RRR + P H K Sbjct: 61 VVVADPQLARQVF--TSSPEELGNIQPNLSRMFGSGSVFALDGDDHRRRRRLLAPPFHGK 118 Query: 283 FVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVF 429 + + + + R + A + M +TL+ I +A+F Sbjct: 119 SMKNYETIIEEETLRETANWPQGQAFATLPSM----MHITLNAILRAIF 163
>C71B4_ARATH (O65786) Cytochrome P450 71B4 (EC 1.14.-.-)| Length = 504 Score = 32.3 bits (72), Expect = 0.96 Identities = 38/172 (22%), Positives = 74/172 (43%), Gaps = 9/172 (5%) Frame = +1 Query: 43 LYDHFLTHGGLFRLNLGPKSFVIVSDPDIAKHILRDNS-KAYSKGILAEILEFV-----M 204 L+D HG + L LG V++S + A+ L+ + + S+ I F + Sbjct: 56 LHDLSKKHGPVMHLRLGFAPMVVISSSEAAEEALKTHDLECCSRPITMASRVFSRNGKDI 115 Query: 205 GTGLIPADGEVWR-VRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEME 381 G G+ G+ WR +R+ ++ K V + + + + +KL + A++ V++ Sbjct: 116 GFGVY---GDEWRELRKLSVREFFSVKKVQSFKYIREEENDLMIKKLKELASKQSPVDLS 172 Query: 382 SLFSRLTLDVIGKAVFNYD-FDSLSYDNGMV-EAVYVTLREAEMRSTSPIPT 531 + LT +I + F FD+ D + E ++ +L R + PT Sbjct: 173 KILFGLTASIIFRTAFGQSFFDNKHVDQESIKELMFESLSNMTFRFSDFFPT 224
>CP52G_CANTR (P30609) Cytochrome P450 52A7 (EC 1.14.14.-) (CYPLIIA7)| (Alkane-inducible P450-ALK4) Length = 507 Score = 32.3 bits (72), Expect = 0.96 Identities = 25/115 (21%), Positives = 48/115 (41%) Frame = +1 Query: 106 VIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVRRRAIVPSLHQKF 285 + DP+ K +L +S G + + ++G G+ DGE W+ R + P +F Sbjct: 91 IFTRDPENIKALLATQFNDFSLGGRIKFFKPLLGYGIFTLDGEGWKHSRAMLRP----QF 146 Query: 286 VTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVFNYDFDSL 450 E + + K + + +++ LF R T+D + +F +SL Sbjct: 147 AREQLPMSPSLEPHFNVKA-YPQEQRWVFDIQELFFRFTVDSATEFLFGESVNSL 200
>CP2C7_RAT (P05179) Cytochrome P450 2C7 (EC 1.14.14.1) (CYPIIC7) (P450F)| (PTF1) Length = 490 Score = 32.3 bits (72), Expect = 0.96 Identities = 20/66 (30%), Positives = 33/66 (50%), Gaps = 1/66 (1%) Frame = +1 Query: 61 THGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYS-KGILAEILEFVMGTGLIPADGEV 237 T+G +F L LG + VI+ + K L DN + +S +G G G++ ++G Sbjct: 60 TYGPVFTLYLGSQPTVILHGYEAIKEALIDNGEKFSGRGSYPMNENVTKGFGIVFSNGNR 119 Query: 238 WRVRRR 255 W+ RR Sbjct: 120 WKEMRR 125
>CP306_DROME (Q9VWR5) Cytochrome P450 306a1 (EC 1.14.-.-) (CYPCCCVIA1) (Phantom| protein) (Dmphm) Length = 574 Score = 32.3 bits (72), Expect = 0.96 Identities = 25/100 (25%), Positives = 44/100 (44%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWR 243 +GG+F L +G V++SD + + R + + L + G G+I A ++WR Sbjct: 80 YGGIFELKMGRVPTVVLSDAALVRDFFRRDVMT-GRAPLYLTHGIMGGFGIICAQEDIWR 138 Query: 244 VRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEG 363 RR + L +T + G L +L++ A G Sbjct: 139 HARRETIDWLKALGMT-------RRPGELRARLERRIARG 171
>GAT1_YEAST (P43574) Transcriptional regulatory protein GAT1| Length = 510 Score = 32.3 bits (72), Expect = 0.96 Identities = 33/117 (28%), Positives = 48/117 (41%), Gaps = 6/117 (5%) Frame = -3 Query: 503 SASRSVTYTASTIPLSYDNESKS*LNTAFPMTSNVSRENKDSISTISPSAAALSNFSHSR 324 SAS+ ++ AS P D S + F T+N+ N +SI+ +N SH+ Sbjct: 175 SASQRASHNASGFPNFLDTSCSSSFDDHFIFTNNLPFLNNNSIN---------NNHSHNS 225 Query: 323 PEAFPKRPIISVTNF*CNDGTMARRRT------RQTSPSAGIRPVPITNSSISARIP 171 I + TN N T A T R SPS ++P NSS+ + P Sbjct: 226 SHNNNSPSIANNTNANTNTNTSASTNTNSPLLRRNPSPSI-VKPGSRRNSSVRKKKP 281
>CP2J2_HUMAN (P51589) Cytochrome P450 2J2 (EC 1.14.14.1) (CYPIIJ2) (Arachidonic| acid epoxygenase) Length = 502 Score = 32.0 bits (71), Expect = 1.3 Identities = 19/71 (26%), Positives = 35/71 (49%), Gaps = 1/71 (1%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMG-TGLIPADGEVW 240 +G LF L LG S V+++ + K L + + + + E + GLI + G+ W Sbjct: 75 YGNLFSLELGDISAVLITGLPLIKEALIHMDQNFGNRPVTPMREHIFKKNGLIMSSGQAW 134 Query: 241 RVRRRAIVPSL 273 + +RR + +L Sbjct: 135 KEQRRFTLTAL 145
>C76B1_HELTU (O23976) Cytochrome P450 76B1 (EC 1.14.-.-) (7-ethoxycoumarin| O-deethylase) (ECOD) (Phenylurea dealkylase) Length = 490 Score = 31.6 bits (70), Expect = 1.6 Identities = 36/173 (20%), Positives = 67/173 (38%), Gaps = 5/173 (2%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVM----GTGLIPADG 231 HG + L LG + +++S A+ +L+ A+S + + + + Sbjct: 59 HGPIMSLQLGQITTLVISSATAAEEVLKKQDLAFSTRNVPDAVRAYNHERHSISFLHVCT 118 Query: 232 EVWRVRRRAIVPSLHQKFVTEMIG-LFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLD 408 E WR RR + ++ E L K L KAA E V + R +L+ Sbjct: 119 E-WRTLRRIVSSNIFSNSSLEAKQHLRSKKVEELIAYCRKAALSNENVHIGRAAFRTSLN 177 Query: 409 VIGKAVFNYDFDSLSYDNGMVEAVYVTLREAEMRSTSPIPTWKIPIWKDISPR 567 ++ +F+ D D+G +T + T+ + + P+ K I P+ Sbjct: 178 LLSNTIFSKDLTDPYEDSGKEFREVITNIMVDSAKTNLVDVF--PVLKKIDPQ 228
>MEGF6_RAT (O88281) Multiple epidermal growth factor-like domains 6 precursor| (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3) Length = 1574 Score = 31.6 bits (70), Expect = 1.6 Identities = 17/52 (32%), Positives = 23/52 (44%), Gaps = 14/52 (26%) Frame = +3 Query: 180 CRNTGVCD---GHGSDPS*WGGLACSTAC-----------HCTIIASEVCNR 293 CRN G CD G + P W GLAC C +C+ + +C+R Sbjct: 1052 CRNGGRCDPILGQCTCPEGWTGLACENECLPGHYAAGCQLNCSCLHGGICDR 1103
>CP9C1_DROME (Q9W130) Cytochrome P450 9c1 (EC 1.14.-.-) (CYPIXC1)| Length = 522 Score = 31.2 bits (69), Expect = 2.1 Identities = 29/125 (23%), Positives = 53/125 (42%), Gaps = 8/125 (6%) Frame = +1 Query: 112 VSDPDIAKHILRDNSKAYS---KGILAEILEF-VMGTGLIPADGEVWRVRRRAIVPSLHQ 279 +SDP++ + + N ++ KGI + V+ L+ W+ R + P+ Sbjct: 85 LSDPELIRQVGIKNFDTFTNHRKGITEGFNDTSVISKSLLSLRDRRWKQMRSTLTPTFTS 144 Query: 280 KFVTEMIGLFG----KASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVFNYDFDS 447 + +M L +A + +LD +E +E++ F+R T DVI A F +S Sbjct: 145 LKIRQMFELIHFCNVEAVDFVQRQLDAGTSE---LELKDFFTRYTNDVIATAAFGIQVNS 201 Query: 448 LSYDN 462 N Sbjct: 202 FKDPN 206
>CP27B_MOUSE (O35084) 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial| precursor (EC 1.14.13.13) (Cytochrome P450 subfamily XXVIIB polypeptide 1) (Cytochrome p450 27B1) (Calcidiol 1-monooxygenase) (25-OHD-1 alpha-hydroxylase) (25-hydroxyvitamin D(3) Length = 507 Score = 31.2 bits (69), Expect = 2.1 Identities = 20/74 (27%), Positives = 33/74 (44%), Gaps = 4/74 (5%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEF----VMGTGLIPADG 231 +G ++ + G V V+DP + + +LR S + + E GL+ ADG Sbjct: 72 YGPIWSGSFGTLRTVYVADPTLVEQLLRQESHCPERCSFSSWAEHRRRHQRACGLLTADG 131 Query: 232 EVWRVRRRAIVPSL 273 E W+ R + P L Sbjct: 132 EEWQRLRSLLAPLL 145
>CP135_DROME (Q9VGB5) Probable cytochrome P450 313a5 (EC 1.14.-.-)| (CYPCCCXIIIA5) Length = 487 Score = 31.2 bits (69), Expect = 2.1 Identities = 17/94 (18%), Positives = 38/94 (40%) Frame = +1 Query: 88 LGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWRVRRRAIVP 267 +G ++ +P I + I + + ++ + + +G GL+ W RR+ ++P Sbjct: 72 IGLTPVLVTCEPKILEDIFTSPNCSNRSSVVDKAISSCLGLGLLTLKNNHWNERRKLLLP 131 Query: 268 SLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEI 369 S V + + + L L + G+I Sbjct: 132 SFKNNAVLSFVPVLNNEANFLVTLLAEFVDGGDI 165
>FBPC_STRCO (O86751) Ferric cations import ATP-binding protein fbpC (EC| 3.6.3.30) Length = 348 Score = 30.8 bits (68), Expect = 2.8 Identities = 36/145 (24%), Positives = 64/145 (44%), Gaps = 11/145 (7%) Frame = +1 Query: 142 LRDNSKAYSKGILAEILEFVMGTGLIP------ADGEVWRVR-RRAIVPSLHQKFVTEMI 300 +R S+A + +AE+L+ V G + GE RV RA+ P + E + Sbjct: 104 MRGASRAEQQARVAELLQLVGLPGAARRSVAALSGGEQQRVALARALAPRPRLLMLDEPL 163 Query: 301 GLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTLDVIGKAVFNYDFDSLSYDNGMVEAV 480 G +LD++ E +VE+ LF RL V+ ++++D G A+ Sbjct: 164 G-----------QLDRSLRERLVVELRELFGRLGTTVL----------AVTHDQGEAFAL 202 Query: 481 ---YVTLREAEM-RSTSPIPTWKIP 543 V +R+ + +S +P+ W+ P Sbjct: 203 ADRVVVMRDGRIAQSGTPLEVWQRP 227
>MEGF6_MOUSE (Q80V70) Multiple epidermal growth factor-like domains 6 (EGF-like| domain-containing protein 3) (Multiple EGF-like domain protein 3) (Fragment) Length = 656 Score = 30.8 bits (68), Expect = 2.8 Identities = 17/52 (32%), Positives = 22/52 (42%), Gaps = 14/52 (26%) Frame = +3 Query: 180 CRNTGVCD---GHGSDPS*WGGLACSTAC-----------HCTIIASEVCNR 293 CRN G CD G + P W GLAC C +C+ + C+R Sbjct: 134 CRNGGSCDPILGQCTCPEGWTGLACENECLPGHHGAGCRLNCSCLNGGTCDR 185
>CP2E1_MESAU (P51581) Cytochrome P450 2E1 (EC 1.14.14.1) (CYPIIE1) (P450-J)| Length = 493 Score = 30.4 bits (67), Expect = 3.6 Identities = 17/63 (26%), Positives = 30/63 (47%) Frame = +1 Query: 67 GGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWRV 246 G +F L+LG K V++ K +L ++ +S + + M G+I +G W+ Sbjct: 65 GPVFTLHLGSKRIVVLHGYKAVKEVLLNHKNEFSGRGDIPVFQEYMNKGIIFNNGPTWKD 124 Query: 247 RRR 255 RR Sbjct: 125 VRR 127
>HEM6_SYNY3 (P72848) Coproporphyrinogen 3 oxidase, aerobic (EC 1.3.3.3)| (Coproporphyrinogen III oxidase, aerobic) (Coproporphyrinogenase) (Coprogen oxidase) Length = 340 Score = 30.4 bits (67), Expect = 3.6 Identities = 16/58 (27%), Positives = 23/58 (39%) Frame = -2 Query: 267 WYNGTPSNTPNLPISWDQTRAHHKLQYFCKNTLGISLGVVPQDMLSYIWIRDDDERLG 94 W+ G TP P + D HH L+ C T G V + Y +++ E G Sbjct: 136 WFGGGADLTPYYPFAEDAAHFHHTLKNACDQTHGEFYPVFKRWCDEYFYLKHRQEMRG 193
>CP27B_RAT (O35132) 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial| precursor (EC 1.14.13.13) (Cytochrome P450 subfamily XXVIIB polypeptide 1) (Cytochrome p450 27B1) (Calcidiol 1-monooxygenase) (25-OHD-1 alpha-hydroxylase) (25-hydroxyvitamin D(3) 1 Length = 501 Score = 30.4 bits (67), Expect = 3.6 Identities = 20/74 (27%), Positives = 33/74 (44%), Gaps = 4/74 (5%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEF----VMGTGLIPADG 231 +G ++ + G V V+DP + + +LR S + + E GL+ ADG Sbjct: 65 YGPIWSGSFGTLRTVYVADPALVEQLLRQESHCPERCSFSSWSEHRRRHQRACGLLTADG 124 Query: 232 EVWRVRRRAIVPSL 273 E W+ R + P L Sbjct: 125 EEWQRLRSLLAPLL 138
>CP270_MOUSE (Q91W64) Cytochrome P450 2C70 (EC 1.14.14.1) (CYPIIC70)| Length = 489 Score = 30.4 bits (67), Expect = 3.6 Identities = 30/141 (21%), Positives = 54/141 (38%), Gaps = 14/141 (9%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFV-MGTGLIPADGEVW 240 +G +F + LG K V++ K L D +S + +L G G++ ++GE W Sbjct: 61 YGPVFTVYLGMKPTVVLHGYKAMKEALIDQGDEFSDKTDSSLLSRTSQGLGIVFSNGETW 120 Query: 241 RVRRRAIVPSLH-------------QKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEME 381 + RR + L Q+ + M+ K +G C+ Sbjct: 121 KQTRRFSLMVLRSMGMGKKTIEDRIQEEILYMLDALRKTNGSPCDP-------------S 167 Query: 382 SLFSRLTLDVIGKAVFNYDFD 444 L + + +VI +F + FD Sbjct: 168 FLLACVPCNVISTVIFQHRFD 188
>C71E1_SORBI (O48958) Cytochrome P450 71E1 (EC 1.14.13.68)| (4-hydroxyphenylacetaldehyde oxime monooxygenase) Length = 531 Score = 30.4 bits (67), Expect = 3.6 Identities = 34/137 (24%), Positives = 56/137 (40%), Gaps = 6/137 (4%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDN-----SKAYSKGILAEILEFVMGTGLIPAD 228 +G + +L LG V+VS + A+ +L+ + S+ S G + + G P Sbjct: 86 YGPVMQLRLGTVPTVVVSSAEAAREVLKVHDVDCCSRPASPGP-KRLSYDLKNVGFAPY- 143 Query: 229 GEVWRVRRRAI-VPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGEIVEMESLFSRLTL 405 GE WR R+ + L + V + RL LD+AAA + + LT Sbjct: 144 GEYWREMRKLFALELLSMRRVKAACYAREQEMDRLVADLDRAAASKASIVLNDHVFALTD 203 Query: 406 DVIGKAVFNYDFDSLSY 456 +IG F + S + Sbjct: 204 GIIGTVAFGNIYASKQF 220
>CP2C3_RABIT (P00182) Cytochrome P450 2C3 (EC 1.14.14.1) (CYPIIC3) (P450 PBC3)| (P450 form 3B) Length = 489 Score = 30.0 bits (66), Expect = 4.8 Identities = 18/65 (27%), Positives = 30/65 (46%), Gaps = 1/65 (1%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYS-KGILAEILEFVMGTGLIPADGEVW 240 +G +F L G K V++ + L D + +S +GI G G++ + GE W Sbjct: 61 YGSIFTLYFGMKPAVVLYGYEGVIEALIDRGEEFSGRGIFPVFDRVTKGLGIVFSSGEKW 120 Query: 241 RVRRR 255 + RR Sbjct: 121 KETRR 125
>CHS2_USTMA (P30599) Chitin synthase 2 (EC 2.4.1.16) (Chitin-UDP| acetyl-glucosaminyl transferase 2) Length = 1074 Score = 29.6 bits (65), Expect = 6.2 Identities = 31/124 (25%), Positives = 56/124 (45%), Gaps = 3/124 (2%) Frame = -3 Query: 503 SASRSVTYTASTIPLSYDNESKS*LNTAFPMTSNVS--RENKDSISTISPSAAALSNFSH 330 S SRSV++T P +Y N+ P+ SN+S R+ D + PS+++ + + Sbjct: 74 SGSRSVSHT----PAAYTNQGIP------PVPSNLSAARQRSDPSQALPPSSSSYAQDAF 123 Query: 329 SRPEAFPKRPIISVTNF*CNDGTMARRRTRQTSPSAGI-RPVPITNSSISARIPLE*ALE 153 SRP R + N + + T+P+A + P P+ S P + +++ Sbjct: 124 SRPSYSSHRNAPNAPNS-NHPSRWDPNASYDTAPTAPLYDPAPLPGSGQLDADPSQHSID 182 Query: 152 LSLR 141 L +R Sbjct: 183 LGVR 186
>CP8B1_RABIT (O02766) Cytochrome P450 8B1 (EC 1.14.13.95) (CYPVIIIB1)| (7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase) (Sterol 12-alpha-hydroxylase) (7-alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase) Length = 499 Score = 29.6 bits (65), Expect = 6.2 Identities = 15/50 (30%), Positives = 26/50 (52%), Gaps = 5/50 (10%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSK-----AYSKGILAEILEF 198 HG +F + LG + F V DP IL+D + Y+KG++ ++ + Sbjct: 62 HGDVFTVQLGGQYFTFVMDPVSFGPILKDGQRKLDFVEYAKGLVLKVFGY 111
>C76C2_ARATH (O64637) Cytochrome P450 76C2 (EC 1.14.-.-)| Length = 512 Score = 29.6 bits (65), Expect = 6.2 Identities = 29/153 (18%), Positives = 61/153 (39%), Gaps = 6/153 (3%) Frame = +1 Query: 61 THGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSK----GILAEILEFVMGTGLIPAD 228 T+G + L G + V+V+ P+ A+ +LR + S + I + +P Sbjct: 68 TYGPIMSLKFGSLNTVVVTSPEAAREVLRTYDQILSSRTPTNSIRSINHDKVSVVWLPPS 127 Query: 229 GEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGR-LCEKLDKAAAEGEIVEMESLFSRLTL 405 WR+ R+ L E + + L + +++ E V++ L Sbjct: 128 SSRWRLLRKLSATQLFSPQRIEATKTLRENKVKELVSFMSESSEREEAVDISRATFITAL 187 Query: 406 DVIGKAVFNYDFDSL-SYDNGMVEAVYVTLREA 501 ++I +F+ D + S +G+ + + + EA Sbjct: 188 NIISNILFSVDLGNYDSNKSGVFQDTVIGVMEA 220
>AUR1_CANAL (O13332) Aureobasidin A resistance protein homolog| Length = 471 Score = 29.6 bits (65), Expect = 6.2 Identities = 22/67 (32%), Positives = 34/67 (50%), Gaps = 6/67 (8%) Frame = -3 Query: 464 PLSYD------NESKS*LNTAFPMTSNVSRENKDSISTISPSAAALSNFSHSRPEAFPKR 303 PLSY+ N+++S L T S VS + +P A +SNFS SR + + Sbjct: 357 PLSYNYIPVNSNDNESRLYTRVYQESQVSPPQRAE----TPEAFEMSNFSRSRQSSKTQV 412 Query: 302 PIISVTN 282 P+ ++TN Sbjct: 413 PLSNLTN 419
>MSH6_YEAST (Q03834) MutS protein homolog 6| Length = 1242 Score = 29.6 bits (65), Expect = 6.2 Identities = 20/62 (32%), Positives = 28/62 (45%) Frame = -3 Query: 491 SVTYTASTIPLSYDNESKS*LNTAFPMTSNVSRENKDSISTISPSAAALSNFSHSRPEAF 312 S+ T S SY+ S P T N+SR+N S + + + N SHS+P A Sbjct: 209 SLAETTSKKKFSYNTSHSS-----SPFTRNISRDNSKKKSRPNQAPSRSYNPSHSQPSAT 263 Query: 311 PK 306 K Sbjct: 264 SK 265
>SYS_BRAJA (Q89L00) Seryl-tRNA synthetase (EC 6.1.1.11) (Serine--tRNA ligase)| (SerRS) Length = 443 Score = 29.3 bits (64), Expect = 8.1 Identities = 20/72 (27%), Positives = 32/72 (44%), Gaps = 2/72 (2%) Frame = +1 Query: 193 EFVMGTGLIPA--DGEVWRVRRRAIVPSLHQKFVTEMIGLFGKASGRLCEKLDKAAAEGE 366 E + GTG +P D + W ++ + H++ TE +GL A L A Sbjct: 204 EVMFGTGQLPKFEDDQFWAIKGELLASPDHERLKTERLGLIPTAEVSLTN-----LARES 258 Query: 367 IVEMESLFSRLT 402 I++ + L RLT Sbjct: 259 ILDEKQLPMRLT 270
>ALG12_HUMAN (Q9BV10) Dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl-alpha-1,| 6-mannosyltransferase (EC 2.4.1.-) (Mannosyltransferase ALG12 homolog) (hALG12) (Membrane protein SB87) Length = 488 Score = 29.3 bits (64), Expect = 8.1 Identities = 23/69 (33%), Positives = 31/69 (44%) Frame = +1 Query: 37 LPLYDHFLTHGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYSKGILAEILEFVMGTGL 216 L YDH G + R LGP + S P + L + SK YS+ I+ +L + GL Sbjct: 52 LEQYDHLEFPGVVPRTFLGPVVIAVFSSPAVYVLSLLEMSKFYSQLIVRGVLGLGVIFGL 111 Query: 217 IPADGEVWR 243 EV R Sbjct: 112 WTLQKEVRR 120
>CP303_DROME (Q9V399) Probable cytochrome P450 303a1 (EC 1.14.-.-) (CYPCCCIIIA1)| Length = 503 Score = 29.3 bits (64), Expect = 8.1 Identities = 19/69 (27%), Positives = 32/69 (46%), Gaps = 1/69 (1%) Frame = +1 Query: 70 GLFRLNLGPKSFVIVSDPD-IAKHILRDNSKAYSKGILAEILEFVMGTGLIPADGEVWRV 246 G + L +G VI D I++ + ++ GI + F G++ DGE+W Sbjct: 69 GFYGLKIGKDKVVIAYTNDAISEMMTNEDIDGRPDGIFYRLRTFNSRLGVLLTDGEMWVE 128 Query: 247 RRRAIVPSL 273 +RR I+ L Sbjct: 129 QRRFILRHL 137
>C71C1_MAIZE (Q43250) Cytochrome P450 71C1 (EC 1.14.-.-) (Benzoxazineless 4)| Length = 535 Score = 29.3 bits (64), Expect = 8.1 Identities = 16/69 (23%), Positives = 31/69 (44%), Gaps = 3/69 (4%) Frame = +1 Query: 64 HGGLFRLNLGPKSFVIVSDPDIAKHILRDNSKAYS---KGILAEILEFVMGTGLIPADGE 234 H GL + +G ++VS P A+ +LR + + + +A+I+ + G Sbjct: 89 HNGLMLVQVGAVPTIVVSTPQAAEAVLRTHDHVLASRPRNPVADIIRYNSTDVAFAPYGV 148 Query: 235 VWRVRRRAI 261 WR R+ + Sbjct: 149 YWRTARKVV 157 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 86,388,973 Number of Sequences: 219361 Number of extensions: 1901461 Number of successful extensions: 5662 Number of sequences better than 10.0: 202 Number of HSP's better than 10.0 without gapping: 5457 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5635 length of database: 80,573,946 effective HSP length: 106 effective length of database: 57,321,680 effective search space used: 4700377760 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
