ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | baal5a06 |
|---|---|
| Clone Library Name | barley_pub |
>2AAB_ARATH (Q38950) Serine/threonine-protein phosphatase 2A 65 kDa regulatory| subunit A beta isoform (PP2A, subunit A, beta isoform) (AtA beta) Length = 587 Score = 396 bits (1017), Expect = e-110 Identities = 202/209 (96%), Positives = 206/209 (98%) Frame = +3 Query: 3 SVRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEP 182 SVRLLAVEGCAALGKLLEPQDCV HILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEP Sbjct: 217 SVRLLAVEGCAALGKLLEPQDCVQHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEP 276 Query: 183 TRADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVR 362 TR +LVPAYVRLLRDNEAEVRIAAAGKVTKFCRIL+P++AIQHILPCVKELSSDSSQHVR Sbjct: 277 TRTELVPAYVRLLRDNEAEVRIAAAGKVTKFCRILNPEIAIQHILPCVKELSSDSSQHVR 336 Query: 363 SALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQ 542 SALASVIMGMAPVLGKDATIE LLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQ Sbjct: 337 SALASVIMGMAPVLGKDATIEHLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQ 396 Query: 543 SLLPAIVELAEDRHWRVRLAIIEYIPLLA 629 SLLPAIVELAEDRHWRVRLAIIEYIPLLA Sbjct: 397 SLLPAIVELAEDRHWRVRLAIIEYIPLLA 425 Score = 92.0 bits (227), Expect = 1e-18 Identities = 54/208 (25%), Positives = 104/208 (50%) Frame = +3 Query: 6 VRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPT 185 VR+ A ++L P+ + HILP + S D S VR +A+ + + +G + T Sbjct: 296 VRIAAAGKVTKFCRILNPEIAIQHILPCVKELSSDSSQHVRSALASVIMGMAPVLGKDAT 355 Query: 186 RADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRS 365 L+P ++ LL+D +VR+ K+ + +++ L Q +LP + EL+ D VR Sbjct: 356 IEHLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVRL 415 Query: 366 ALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQS 545 A+ I +A LG ++L + + L+D+ +R + L ++ + G + Q Sbjct: 416 AIIEYIPLLASQLGVGFFDDKLGALCMQWLQDKVHSIRDAAANNLKRLAEEFGPEWAMQH 475 Query: 546 LLPAIVELAEDRHWRVRLAIIEYIPLLA 629 ++P ++E+ + H+ R+ I+ + LLA Sbjct: 476 IVPQVLEMVNNPHYLYRMTILRAVSLLA 503 Score = 90.5 bits (223), Expect = 4e-18 Identities = 48/173 (27%), Positives = 90/173 (52%) Frame = +3 Query: 78 ILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPTRADLVPAYVRLLRDNEAEVRIAAA 257 +LP IV ++D+ WRVR + + L +G L ++ L+D +R AAA Sbjct: 398 LLPAIVELAEDRHWRVRLAIIEYIPLLASQLGVGFFDDKLGALCMQWLQDKVHSIRDAAA 457 Query: 258 GKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRSALASVIMGMAPVLGKDATIEQLLP 437 + + P+ A+QHI+P V E+ ++ R + + +APV+G + T +LLP Sbjct: 458 NNLKRLAEEFGPEWAMQHIVPQVLEMVNNPHYLYRMTILRAVSLLAPVMGSEITCSKLLP 517 Query: 438 IFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVR 596 + ++ KD P+++ N+ L + ++ ++ +++ P +VEL+ED VR Sbjct: 518 VVMTASKDRVPNIKFNVAKVLQSLIPIVDQSVVEKTIRPGLVELSEDPDVDVR 570 Score = 81.6 bits (200), Expect = 2e-15 Identities = 47/171 (27%), Positives = 84/171 (49%) Frame = +3 Query: 105 QDKSWRVRYMVANQLYELCEAVGPEPTRADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRI 284 QD VR A L + V + D++ + L +D++ VR+ A ++ Sbjct: 173 QDDMPMVRRAAATNLGKFAATVESAHLKTDVMSMFEDLTQDDQDSVRLLAVEGCAALGKL 232 Query: 285 LSPQLAIQHILPCVKELSSDSSQHVRSALASVIMGMAPVLGKDATIEQLLPIFLSLLKDE 464 L PQ +QHILP + S D S VR +A+ + + +G + T +L+P ++ LL+D Sbjct: 233 LEPQDCVQHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPTRTELVPAYVRLLRDN 292 Query: 465 FPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVRLAIIEYI 617 +VR+ K+ + +++ ++ Q +LP + EL+ D VR A+ I Sbjct: 293 EAEVRIAAAGKVTKFCRILNPEIAIQHILPCVKELSSDSSQHVRSALASVI 343 Score = 65.9 bits (159), Expect = 1e-10 Identities = 44/199 (22%), Positives = 88/199 (44%) Frame = +3 Query: 6 VRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPT 185 VR AVE +G + D V H + ++ + + W + A ++ + P+ Sbjct: 102 VREKAVESLCRVGSQMRESDLVDHFISLVKRLAAGE-WFTARVSACGVFHIAYPSAPDML 160 Query: 186 RADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRS 365 + +L Y +L +D+ VR AAA + KF + ++ ++L+ D VR Sbjct: 161 KTELRSLYTQLCQDDMPMVRRAAATNLGKFAATVESAHLKTDVMSMFEDLTQDDQDSVRL 220 Query: 366 ALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQS 545 + +L ++ +LP+ ++ +D+ VR + ++L ++ + +G + Sbjct: 221 LAVEGCAALGKLLEPQDCVQHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPTRTE 280 Query: 546 LLPAIVELAEDRHWRVRLA 602 L+PA V L D VR+A Sbjct: 281 LVPAYVRLLRDNEAEVRIA 299 Score = 38.1 bits (87), Expect = 0.022 Identities = 26/120 (21%), Positives = 49/120 (40%) Frame = +3 Query: 3 SVRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEP 182 S+R A L + P+ + HI+P ++ + + R + + L +G E Sbjct: 451 SIRDAAANNLKRLAEEFGPEWAMQHIVPQVLEMVNNPHYLYRMTILRAVSLLAPVMGSEI 510 Query: 183 TRADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVR 362 T + L+P + +D ++ A + I+ + + I P + ELS D VR Sbjct: 511 TCSKLLPVVMTASKDRVPNIKFNVAKVLQSLIPIVDQSVVEKTIRPGLVELSEDPDVDVR 570
>2AAG_ARATH (Q38951) Serine/threonine-protein phosphatase 2A 65 kDa regulatory| subunit A gamma isoform (PP2A, subunit A, gamma isoform) (AtA gamma) Length = 587 Score = 395 bits (1016), Expect = e-110 Identities = 203/209 (97%), Positives = 205/209 (98%) Frame = +3 Query: 3 SVRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEP 182 SVRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEP Sbjct: 217 SVRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEP 276 Query: 183 TRADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVR 362 TR DLVPAY RLL DNEAEVRIAAAGKVTKFCRIL+P+LAIQHILPCVKELSSDSSQHVR Sbjct: 277 TRTDLVPAYARLLCDNEAEVRIAAAGKVTKFCRILNPELAIQHILPCVKELSSDSSQHVR 336 Query: 363 SALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQ 542 SALASVIMGMAPVLGKDATIE LLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQ Sbjct: 337 SALASVIMGMAPVLGKDATIEHLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQ 396 Query: 543 SLLPAIVELAEDRHWRVRLAIIEYIPLLA 629 SLLPAIVELAEDRHWRVRLAIIEYIPLLA Sbjct: 397 SLLPAIVELAEDRHWRVRLAIIEYIPLLA 425 Score = 92.8 bits (229), Expect = 7e-19 Identities = 55/208 (26%), Positives = 104/208 (50%) Frame = +3 Query: 6 VRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPT 185 VR+ A ++L P+ + HILP + S D S VR +A+ + + +G + T Sbjct: 296 VRIAAAGKVTKFCRILNPELAIQHILPCVKELSSDSSQHVRSALASVIMGMAPVLGKDAT 355 Query: 186 RADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRS 365 L+P ++ LL+D +VR+ K+ + +++ L Q +LP + EL+ D VR Sbjct: 356 IEHLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVRL 415 Query: 366 ALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQS 545 A+ I +A LG E+L + + L+D+ +R + L ++ + G + Q Sbjct: 416 AIIEYIPLLASQLGVGFFDEKLGALCMQWLQDKVHSIREAAANNLKRLAEEFGPEWAMQH 475 Query: 546 LLPAIVELAEDRHWRVRLAIIEYIPLLA 629 ++P ++E+ + H+ R+ I+ + LLA Sbjct: 476 IVPQVLEMINNPHYLYRMTILRAVSLLA 503 Score = 87.0 bits (214), Expect = 4e-17 Identities = 47/173 (27%), Positives = 87/173 (50%) Frame = +3 Query: 78 ILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPTRADLVPAYVRLLRDNEAEVRIAAA 257 +LP IV ++D+ WRVR + + L +G L ++ L+D +R AAA Sbjct: 398 LLPAIVELAEDRHWRVRLAIIEYIPLLASQLGVGFFDEKLGALCMQWLQDKVHSIREAAA 457 Query: 258 GKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRSALASVIMGMAPVLGKDATIEQLLP 437 + + P+ A+QHI+P V E+ ++ R + + +APV+G + T +LLP Sbjct: 458 NNLKRLAEEFGPEWAMQHIVPQVLEMINNPHYLYRMTILRAVSLLAPVMGSEITCSKLLP 517 Query: 438 IFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVR 596 ++ KD P+++ N+ + + ++ ++ + P +VEL+ED VR Sbjct: 518 AVITASKDRVPNIKFNVAKMMQSLIPIVDQAVVENMIRPCLVELSEDPDVDVR 570 Score = 76.6 bits (187), Expect = 5e-14 Identities = 46/171 (26%), Positives = 80/171 (46%) Frame = +3 Query: 105 QDKSWRVRYMVANQLYELCEAVGPEPTRADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRI 284 QD VR A L + + + D++ + L +D++ VR+ A ++ Sbjct: 173 QDDMPMVRRAAATNLGKFAATIESAHLKTDIMSMFEDLTQDDQDSVRLLAVEGCAALGKL 232 Query: 285 LSPQLAIQHILPCVKELSSDSSQHVRSALASVIMGMAPVLGKDATIEQLLPIFLSLLKDE 464 L PQ + HILP + S D S VR +A+ + + +G + T L+P + LL D Sbjct: 233 LEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPTRTDLVPAYARLLCDN 292 Query: 465 FPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVRLAIIEYI 617 +VR+ K+ + +++ +L Q +LP + EL+ D VR A+ I Sbjct: 293 EAEVRIAAAGKVTKFCRILNPELAIQHILPCVKELSSDSSQHVRSALASVI 343 Score = 62.4 bits (150), Expect = 1e-09 Identities = 45/199 (22%), Positives = 85/199 (42%) Frame = +3 Query: 6 VRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPT 185 VR AV+ +G + D V H P+ S + W + A ++ + P+ Sbjct: 102 VREKAVDSLCRIGAQMRESDLVEHFTPLAKRLSAGE-WFTARVSACGIFHIAYPSAPDVL 160 Query: 186 RADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRS 365 + +L Y +L +D+ VR AAA + KF + I+ ++L+ D VR Sbjct: 161 KTELRSIYGQLCQDDMPMVRRAAATNLGKFAATIESAHLKTDIMSMFEDLTQDDQDSVRL 220 Query: 366 ALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQS 545 + +L + +LP+ ++ +D+ VR + ++L ++ + +G + Sbjct: 221 LAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPTRTD 280 Query: 546 LLPAIVELAEDRHWRVRLA 602 L+PA L D VR+A Sbjct: 281 LVPAYARLLCDNEAEVRIA 299 Score = 45.1 bits (105), Expect = 2e-04 Identities = 28/120 (23%), Positives = 50/120 (41%) Frame = +3 Query: 3 SVRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEP 182 S+R A L + P+ + HI+P ++ + + R + + L +G E Sbjct: 451 SIREAAANNLKRLAEEFGPEWAMQHIVPQVLEMINNPHYLYRMTILRAVSLLAPVMGSEI 510 Query: 183 TRADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVR 362 T + L+PA + +D ++ A + I+ + I PC+ ELS D VR Sbjct: 511 TCSKLLPAVITASKDRVPNIKFNVAKMMQSLIPIVDQAVVENMIRPCLVELSEDPDVDVR 570
>2AAA_ARATH (Q38845) Serine/threonine-protein phosphatase 2A 65 kDa regulatory| subunit A alpha isoform (PP2A, subunit A, alpha isoform) (PR-65 A) (AtA alpha) (Protein enhanced ethylene-response 1) (Protein ROOTS CURL IN NAPHTHYLPHTHALAMIC ACID 1) Length = 588 Score = 389 bits (1000), Expect = e-108 Identities = 198/209 (94%), Positives = 205/209 (98%) Frame = +3 Query: 3 SVRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEP 182 SVRLLAVEGCAALGKLLEPQDCVA ILPVIVNFSQDKSWRVRYMVANQLYELCEAVGP+ Sbjct: 217 SVRLLAVEGCAALGKLLEPQDCVARILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPDC 276 Query: 183 TRADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVR 362 TR DLVPAYVRLLRDNEAEVRIAAAGKVTKFCR+L+P+LAIQHILPCVKELSSDSSQHVR Sbjct: 277 TRTDLVPAYVRLLRDNEAEVRIAAAGKVTKFCRLLNPELAIQHILPCVKELSSDSSQHVR 336 Query: 363 SALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQ 542 SALASVIMGMAP+LGKD+TIE LLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQ Sbjct: 337 SALASVIMGMAPILGKDSTIEHLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQ 396 Query: 543 SLLPAIVELAEDRHWRVRLAIIEYIPLLA 629 SLLPAIVELAEDRHWRVRLAIIEY+PLLA Sbjct: 397 SLLPAIVELAEDRHWRVRLAIIEYVPLLA 425 Score = 89.0 bits (219), Expect = 1e-17 Identities = 53/208 (25%), Positives = 104/208 (50%) Frame = +3 Query: 6 VRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPT 185 VR+ A +LL P+ + HILP + S D S VR +A+ + + +G + T Sbjct: 296 VRIAAAGKVTKFCRLLNPELAIQHILPCVKELSSDSSQHVRSALASVIMGMAPILGKDST 355 Query: 186 RADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRS 365 L+P ++ LL+D +VR+ K+ + +++ L Q +LP + EL+ D VR Sbjct: 356 IEHLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVRL 415 Query: 366 ALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQS 545 A+ + +A LG ++L + + L+D+ +R + L ++ + G + Q Sbjct: 416 AIIEYVPLLASQLGIGFFDDKLGALCMQWLQDKVYSIREAAANNLKRLAEEFGPEWAMQH 475 Query: 546 LLPAIVELAEDRHWRVRLAIIEYIPLLA 629 L+P ++++ + H+ R+ ++ I L+A Sbjct: 476 LVPQVLDMVNNPHYLHRMMVLRAISLMA 503 Score = 81.3 bits (199), Expect = 2e-15 Identities = 45/173 (26%), Positives = 87/173 (50%) Frame = +3 Query: 78 ILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPTRADLVPAYVRLLRDNEAEVRIAAA 257 +LP IV ++D+ WRVR + + L +G L ++ L+D +R AAA Sbjct: 398 LLPAIVELAEDRHWRVRLAIIEYVPLLASQLGIGFFDDKLGALCMQWLQDKVYSIREAAA 457 Query: 258 GKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRSALASVIMGMAPVLGKDATIEQLLP 437 + + P+ A+QH++P V ++ ++ R + I MAPV+G + T + LP Sbjct: 458 NNLKRLAEEFGPEWAMQHLVPQVLDMVNNPHYLHRMMVLRAISLMAPVMGSEITCSKFLP 517 Query: 438 IFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVR 596 + + KD P+++ N+ L + ++ ++ +++ +V+L+ED VR Sbjct: 518 VVVEASKDRVPNIKFNVAKLLQSLIPIVDQSVVDKTIRQCLVDLSEDPDVDVR 570 Score = 73.9 bits (180), Expect = 4e-13 Identities = 45/165 (27%), Positives = 80/165 (48%) Frame = +3 Query: 123 VRYMVANQLYELCEAVGPEPTRADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLA 302 VR A+ L + V A+++ + L +D++ VR+ A ++L PQ Sbjct: 179 VRRAAASNLGKFATTVESTFLIAEIMTMFDDLTKDDQDSVRLLAVEGCAALGKLLEPQDC 238 Query: 303 IQHILPCVKELSSDSSQHVRSALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRL 482 + ILP + S D S VR +A+ + + +G D T L+P ++ LL+D +VR+ Sbjct: 239 VARILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPDCTRTDLVPAYVRLLRDNEAEVRI 298 Query: 483 NIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVRLAIIEYI 617 K+ + +++ +L Q +LP + EL+ D VR A+ I Sbjct: 299 AAAGKVTKFCRLLNPELAIQHILPCVKELSSDSSQHVRSALASVI 343 Score = 67.4 bits (163), Expect = 3e-11 Identities = 46/199 (23%), Positives = 88/199 (44%) Frame = +3 Query: 6 VRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPT 185 VR AVE +G ++ D V +P++ + + W + A ++ + + Sbjct: 102 VREKAVESLCKIGSQMKENDLVESFVPLVKRLAGGE-WFAARVSACGIFHVAYQGCTDVL 160 Query: 186 RADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRS 365 + +L Y +L +D+ VR AAA + KF + I I+ +L+ D VR Sbjct: 161 KTELRATYSQLCKDDMPMVRRAAASNLGKFATTVESTFLIAEIMTMFDDLTKDDQDSVRL 220 Query: 366 ALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQS 545 + +L + ++LP+ ++ +D+ VR + ++L ++ + +G D Sbjct: 221 LAVEGCAALGKLLEPQDCVARILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPDCTRTD 280 Query: 546 LLPAIVELAEDRHWRVRLA 602 L+PA V L D VR+A Sbjct: 281 LVPAYVRLLRDNEAEVRIA 299
>2AAA_PEA (P36875) Protein phosphatase PP2A regulatory subunit A (PR65)| (Fragment) Length = 395 Score = 382 bits (982), Expect = e-106 Identities = 196/209 (93%), Positives = 203/209 (97%) Frame = +3 Query: 3 SVRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEP 182 S R LAVEGCAALGKLLEPQDC+AHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGP+ Sbjct: 24 SFRFLAVEGCAALGKLLEPQDCLAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPDS 83 Query: 183 TRADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVR 362 T+ +LVPAYVRLLRDN AEVRIAAAGKV+KF RILSP+LAIQHILPCVKELS+DSSQHVR Sbjct: 84 TKTELVPAYVRLLRDNVAEVRIAAAGKVSKFSRILSPELAIQHILPCVKELSTDSSQHVR 143 Query: 363 SALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQ 542 SALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQ Sbjct: 144 SALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQ 203 Query: 543 SLLPAIVELAEDRHWRVRLAIIEYIPLLA 629 SLLPAIVELAEDRHWRVRLAIIEYIPLLA Sbjct: 204 SLLPAIVELAEDRHWRVRLAIIEYIPLLA 232 Score = 90.5 bits (223), Expect = 4e-18 Identities = 52/174 (29%), Positives = 89/174 (51%), Gaps = 1/174 (0%) Frame = +3 Query: 78 ILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPTRADLVPAYVRLLRDNEAEVRIAAA 257 +LP IV ++D+ WRVR + + L +G L ++ L+D E +R AAA Sbjct: 205 LLPAIVELAEDRHWRVRLAIIEYIPLLASQLGVGFFDDKLGALIMQWLKDKEYSIRNAAA 264 Query: 258 GKVTKFC-RILSPQLAIQHILPCVKELSSDSSQHVRSALASVIMGMAPVLGKDATIEQLL 434 V + P+ A+QHI+P V ++ +D R + I +APVLG + T LL Sbjct: 265 NNVKRLAAEEFGPEWAMQHIIPQVLDMINDPHYLYRMTILHAISLLAPVLGSEITSTNLL 324 Query: 435 PIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVR 596 P+ ++ KD P+++ N+ L + ++ ++ ++ P +VEL+ED VR Sbjct: 325 PLVVNASKDRVPNIKFNVAKVLQSLIPIVDESVVESTIRPCLVELSEDPDVDVR 378 Score = 90.1 bits (222), Expect = 5e-18 Identities = 57/211 (27%), Positives = 105/211 (49%), Gaps = 3/211 (1%) Frame = +3 Query: 6 VRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPT 185 VR+ A + ++L P+ + HILP + S D S VR +A+ + + +G + T Sbjct: 103 VRIAAAGKVSKFSRILSPELAIQHILPCVKELSTDSSQHVRSALASVIMGMAPVLGKDAT 162 Query: 186 RADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRS 365 L+P ++ LL+D +VR+ K+ + +++ L Q +LP + EL+ D VR Sbjct: 163 IEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVRL 222 Query: 366 ALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVR---LNIISKLDQVNQVIGIDLL 536 A+ I +A LG ++L + + LKD+ +R N + +L + G + Sbjct: 223 AIIEYIPLLASQLGVGFFDDKLGALIMQWLKDKEYSIRNAAANNVKRL--AAEEFGPEWA 280 Query: 537 SQSLLPAIVELAEDRHWRVRLAIIEYIPLLA 629 Q ++P ++++ D H+ R+ I+ I LLA Sbjct: 281 MQHIIPQVLDMINDPHYLYRMTILHAISLLA 311 Score = 77.4 bits (189), Expect = 3e-14 Identities = 40/144 (27%), Positives = 75/144 (52%) Frame = +3 Query: 186 RADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRS 365 + D++ + L +D++ R A ++L PQ + HILP + S D S VR Sbjct: 7 KTDIMSVFDDLTQDDQDSFRFLAVEGCAALGKLLEPQDCLAHILPVIVNFSQDKSWRVRY 66 Query: 366 ALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQS 545 +A+ + + +G D+T +L+P ++ LL+D +VR+ K+ + ++++ +L Q Sbjct: 67 MVANQLYELCEAVGPDSTKTELVPAYVRLLRDNVAEVRIAAAGKVSKFSRILSPELAIQH 126 Query: 546 LLPAIVELAEDRHWRVRLAIIEYI 617 +LP + EL+ D VR A+ I Sbjct: 127 ILPCVKELSTDSSQHVRSALASVI 150 Score = 53.9 bits (128), Expect = 4e-07 Identities = 32/145 (22%), Positives = 65/145 (44%), Gaps = 1/145 (0%) Frame = +3 Query: 87 VIVNFSQDKSWRVRYMVANQLYELC-EAVGPEPTRADLVPAYVRLLRDNEAEVRIAAAGK 263 +I+ + +DK + +R AN + L E GPE ++P + ++ D R+ Sbjct: 247 LIMQWLKDKEYSIRNAAANNVKRLAAEEFGPEWAMQHIIPQVLDMINDPHYLYRMTILHA 306 Query: 264 VTKFCRILSPQLAIQHILPCVKELSSDSSQHVRSALASVIMGMAPVLGKDATIEQLLPIF 443 ++ +L ++ ++LP V S D +++ +A V+ + P++ + + P Sbjct: 307 ISLLAPVLGSEITSTNLLPLVVNASKDRVPNIKFNVAKVLQSLIPIVDESVVESTIRPCL 366 Query: 444 LSLLKDEFPDVRLNIISKLDQVNQV 518 + L +D DVR L +QV Sbjct: 367 VELSEDPDVDVRFFASQALQSSDQV 391 Score = 45.1 bits (105), Expect = 2e-04 Identities = 25/102 (24%), Positives = 45/102 (44%) Frame = +3 Query: 57 PQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPTRADLVPAYVRLLRDNEA 236 P+ + HI+P +++ D + R + + + L +G E T +L+P V +D Sbjct: 277 PEWAMQHIIPQVLDMINDPHYLYRMTILHAISLLAPVLGSEITSTNLLPLVVNASKDRVP 336 Query: 237 EVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVR 362 ++ A + I+ + I PC+ ELS D VR Sbjct: 337 NIKFNVAKVLQSLIPIVDESVVESTIRPCLVELSEDPDVDVR 378 Score = 37.7 bits (86), Expect = 0.028 Identities = 21/83 (25%), Positives = 40/83 (48%) Frame = +3 Query: 9 RLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPTR 188 R+ + + L +L + ++LP++VN S+D+ +++ VA L L V Sbjct: 300 RMTILHAISLLAPVLGSEITSTNLLPLVVNASKDRVPNIKFNVAKVLQSLIPIVDESVVE 359 Query: 189 ADLVPAYVRLLRDNEAEVRIAAA 257 + + P V L D + +VR A+ Sbjct: 360 STIRPCLVELSEDPDVDVRFFAS 382
>2AAA_PIG (P54612) Serine/threonine-protein phosphatase 2A 65 kDa regulatory| subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform) Length = 588 Score = 256 bits (655), Expect = 3e-68 Identities = 136/213 (63%), Positives = 167/213 (78%), Gaps = 4/213 (1%) Frame = +3 Query: 3 SVRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEP 182 SVRLLAVE C + +LL +D A ++P + ++DKSWRVRYMVA++ EL +AVGPE Sbjct: 218 SVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEI 277 Query: 183 TRADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQ----LAIQHILPCVKELSSDSS 350 T+ DLVPA+ L++D EAEVR AA+ KV +FC LS + + ILPC+KEL SD++ Sbjct: 278 TKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENVIMTQILPCIKELVSDAN 337 Query: 351 QHVRSALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGID 530 QHV+SALASVIMG++P+LGKD TIE LLP+FL+ LKDE P+VRLNIIS LD VN+VIGI Sbjct: 338 QHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIR 397 Query: 531 LLSQSLLPAIVELAEDRHWRVRLAIIEYIPLLA 629 LSQSLLPAIVELAED WRVRLAIIEY+PLLA Sbjct: 398 QLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLA 430 Score = 69.3 bits (168), Expect = 9e-12 Identities = 50/199 (25%), Positives = 85/199 (42%) Frame = +3 Query: 6 VRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPT 185 VR AVE A+ P D AH +P++ + W A L+ +C Sbjct: 103 VRDKAVESLRAISHEHSPSDLEAHFVPLVKRLAGG-DWFTSRTSACGLFSVCYPRVSSAV 161 Query: 186 RADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRS 365 +A+L + L D+ VR AAA K+ +F ++L I+P L+SD VR Sbjct: 162 KAELRQYFRNLCSDDTPMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRL 221 Query: 366 ALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQS 545 + +A +L ++ ++P +D+ VR + K ++ + +G ++ Sbjct: 222 LAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTD 281 Query: 546 LLPAIVELAEDRHWRVRLA 602 L+PA L +D VR A Sbjct: 282 LVPAFQNLMKDCEAEVRAA 300 Score = 68.9 bits (167), Expect = 1e-11 Identities = 49/208 (23%), Positives = 90/208 (43%) Frame = +3 Query: 6 VRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPT 185 VRL + + +++ + +LP IV ++D WRVR + + L +G E Sbjct: 379 VRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFF 438 Query: 186 RADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRS 365 L + L D+ +R AA + K + A I+P V +S D + R Sbjct: 439 DEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATIIPKVLAMSGDPNYLHRM 498 Query: 366 ALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQS 545 I ++ V G+D T + +LP L + D +VR N+ L ++ ++ L Sbjct: 499 TTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANVRFNVAKSLQKIGPILDNSTLQSE 558 Query: 546 LLPAIVELAEDRHWRVRLAIIEYIPLLA 629 + P + +L +D+ V+ E + +L+ Sbjct: 559 VKPILEKLTQDQDVDVKYFAQEALTVLS 586 Score = 63.5 bits (153), Expect = 5e-10 Identities = 41/178 (23%), Positives = 82/178 (46%), Gaps = 4/178 (2%) Frame = +3 Query: 96 NFSQDKSWRVRYMVANQLYELCEAVGPEPTRADLVPAYVRLLRDNEAEVRIAAAGKVTKF 275 N D + VR A++L E + + + +++++P + L D + VR+ A Sbjct: 171 NLCSDDTPMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNI 230 Query: 276 CRILSPQLAIQHILPCVKELSSDSSQHVRSALASVIMGMAPVLGKDATIEQLLPIFLSLL 455 ++L + ++P +++ + D S VR +A + +G + T L+P F +L+ Sbjct: 231 AQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLM 290 Query: 456 KDEFPDVRLNIISKLDQVNQVIGID----LLSQSLLPAIVELAEDRHWRVRLAIIEYI 617 KD +VR K+ + + + D ++ +LP I EL D + V+ A+ I Sbjct: 291 KDCEAEVRAAASHKVKEFCENLSADCRENVIMTQILPCIKELVSDANQHVKSALASVI 348 Score = 59.7 bits (143), Expect = 7e-09 Identities = 45/202 (22%), Positives = 92/202 (45%) Frame = +3 Query: 24 EGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPTRADLVP 203 E C L + ILP I D + V+ +A+ + L +G + T L+P Sbjct: 307 EFCENLSADCRENVIMTQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLP 366 Query: 204 AYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRSALASVI 383 ++ L+D EVR+ + ++ + Q +LP + EL+ D+ VR A+ + Sbjct: 367 LFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYM 426 Query: 384 MGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIV 563 +A LG + E+L + ++ L D +R S L ++ + G + +++P ++ Sbjct: 427 PLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATIIPKVL 486 Query: 564 ELAEDRHWRVRLAIIEYIPLLA 629 ++ D ++ R+ + I +L+ Sbjct: 487 AMSGDPNYLHRMTTLFCINVLS 508 Score = 58.9 bits (141), Expect = 1e-08 Identities = 52/203 (25%), Positives = 86/203 (42%), Gaps = 1/203 (0%) Frame = +3 Query: 6 VRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPT 185 V L E L+ + V +LP + + + + VR L + P Sbjct: 64 VLLALAEQLGTFTTLVGGPEYVHCLLPPLESLATVEETVVRDKAVESLRAISHEHSPSDL 123 Query: 186 RADLVPAYVRLLRDNEAEVRIAAAGKVTK-FCRILSPQLAIQHILPCVKELSSDSSQHVR 362 A VP RL + R +A G + + R+ S A + + L SD + VR Sbjct: 124 EAHFVPLVKRLAGGDWFTSRTSACGLFSVCYPRVSSAVKA--ELRQYFRNLCSDDTPMVR 181 Query: 363 SALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQ 542 A AS + A VL D +++P+F +L DE VRL + + Q++ + L Sbjct: 182 RAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEA 241 Query: 543 SLLPAIVELAEDRHWRVRLAIIE 611 ++P + + AED+ WRVR + + Sbjct: 242 LVMPTLRQAAEDKSWRVRYMVAD 264 Score = 30.4 bits (67), Expect = 4.5 Identities = 17/62 (27%), Positives = 31/62 (50%) Frame = +3 Query: 432 LPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVRLAIIE 611 + + + L++E +RLN I KL + +G++ LLP + + D V LA+ E Sbjct: 12 IAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIYDED-EVLLALAE 70 Query: 612 YI 617 + Sbjct: 71 QL 72
>2AAA_MOUSE (Q76MZ3) Serine/threonine-protein phosphatase 2A 65 kDa regulatory| subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform) Length = 588 Score = 256 bits (655), Expect = 3e-68 Identities = 136/213 (63%), Positives = 167/213 (78%), Gaps = 4/213 (1%) Frame = +3 Query: 3 SVRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEP 182 SVRLLAVE C + +LL +D A ++P + ++DKSWRVRYMVA++ EL +AVGPE Sbjct: 218 SVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEI 277 Query: 183 TRADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQ----LAIQHILPCVKELSSDSS 350 T+ DLVPA+ L++D EAEVR AA+ KV +FC LS + + ILPC+KEL SD++ Sbjct: 278 TKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENVIMTQILPCIKELVSDAN 337 Query: 351 QHVRSALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGID 530 QHV+SALASVIMG++P+LGKD TIE LLP+FL+ LKDE P+VRLNIIS LD VN+VIGI Sbjct: 338 QHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIR 397 Query: 531 LLSQSLLPAIVELAEDRHWRVRLAIIEYIPLLA 629 LSQSLLPAIVELAED WRVRLAIIEY+PLLA Sbjct: 398 QLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLA 430 Score = 69.3 bits (168), Expect = 9e-12 Identities = 50/199 (25%), Positives = 85/199 (42%) Frame = +3 Query: 6 VRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPT 185 VR AVE A+ P D AH +P++ + W A L+ +C Sbjct: 103 VRDKAVESLRAISHEHSPSDLEAHFVPLVKRLAGG-DWFTSRTSACGLFSVCYPRVSSAV 161 Query: 186 RADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRS 365 +A+L + L D+ VR AAA K+ +F ++L I+P L+SD VR Sbjct: 162 KAELRQYFRNLCSDDTPMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRL 221 Query: 366 ALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQS 545 + +A +L ++ ++P +D+ VR + K ++ + +G ++ Sbjct: 222 LAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTD 281 Query: 546 LLPAIVELAEDRHWRVRLA 602 L+PA L +D VR A Sbjct: 282 LVPAFQNLMKDCEAEVRAA 300 Score = 68.9 bits (167), Expect = 1e-11 Identities = 49/208 (23%), Positives = 90/208 (43%) Frame = +3 Query: 6 VRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPT 185 VRL + + +++ + +LP IV ++D WRVR + + L +G E Sbjct: 379 VRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFF 438 Query: 186 RADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRS 365 L + L D+ +R AA + K + A I+P V +S D + R Sbjct: 439 DEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATIIPKVLAMSGDPNYLHRM 498 Query: 366 ALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQS 545 I ++ V G+D T + +LP L + D +VR N+ L ++ ++ L Sbjct: 499 TTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANVRFNVAKSLQKIGPILDNSTLQSE 558 Query: 546 LLPAIVELAEDRHWRVRLAIIEYIPLLA 629 + P + +L +D+ V+ E + +L+ Sbjct: 559 VKPILEKLTQDQDVDVKYFAQEALTVLS 586 Score = 63.5 bits (153), Expect = 5e-10 Identities = 41/178 (23%), Positives = 82/178 (46%), Gaps = 4/178 (2%) Frame = +3 Query: 96 NFSQDKSWRVRYMVANQLYELCEAVGPEPTRADLVPAYVRLLRDNEAEVRIAAAGKVTKF 275 N D + VR A++L E + + + +++++P + L D + VR+ A Sbjct: 171 NLCSDDTPMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNI 230 Query: 276 CRILSPQLAIQHILPCVKELSSDSSQHVRSALASVIMGMAPVLGKDATIEQLLPIFLSLL 455 ++L + ++P +++ + D S VR +A + +G + T L+P F +L+ Sbjct: 231 AQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLM 290 Query: 456 KDEFPDVRLNIISKLDQVNQVIGID----LLSQSLLPAIVELAEDRHWRVRLAIIEYI 617 KD +VR K+ + + + D ++ +LP I EL D + V+ A+ I Sbjct: 291 KDCEAEVRAAASHKVKEFCENLSADCRENVIMTQILPCIKELVSDANQHVKSALASVI 348 Score = 59.7 bits (143), Expect = 7e-09 Identities = 45/202 (22%), Positives = 92/202 (45%) Frame = +3 Query: 24 EGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPTRADLVP 203 E C L + ILP I D + V+ +A+ + L +G + T L+P Sbjct: 307 EFCENLSADCRENVIMTQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLP 366 Query: 204 AYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRSALASVI 383 ++ L+D EVR+ + ++ + Q +LP + EL+ D+ VR A+ + Sbjct: 367 LFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYM 426 Query: 384 MGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIV 563 +A LG + E+L + ++ L D +R S L ++ + G + +++P ++ Sbjct: 427 PLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATIIPKVL 486 Query: 564 ELAEDRHWRVRLAIIEYIPLLA 629 ++ D ++ R+ + I +L+ Sbjct: 487 AMSGDPNYLHRMTTLFCINVLS 508 Score = 58.9 bits (141), Expect = 1e-08 Identities = 52/203 (25%), Positives = 86/203 (42%), Gaps = 1/203 (0%) Frame = +3 Query: 6 VRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPT 185 V L E L+ + V +LP + + + + VR L + P Sbjct: 64 VLLALAEQLGTFTTLVGGPEYVHCLLPPLESLATVEETVVRDKAVESLRAISHEHSPSDL 123 Query: 186 RADLVPAYVRLLRDNEAEVRIAAAGKVTK-FCRILSPQLAIQHILPCVKELSSDSSQHVR 362 A VP RL + R +A G + + R+ S A + + L SD + VR Sbjct: 124 EAHFVPLVKRLAGGDWFTSRTSACGLFSVCYPRVSSAVKA--ELRQYFRNLCSDDTPMVR 181 Query: 363 SALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQ 542 A AS + A VL D +++P+F +L DE VRL + + Q++ + L Sbjct: 182 RAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEA 241 Query: 543 SLLPAIVELAEDRHWRVRLAIIE 611 ++P + + AED+ WRVR + + Sbjct: 242 LVMPTLRQAAEDKSWRVRYMVAD 264 Score = 30.4 bits (67), Expect = 4.5 Identities = 17/62 (27%), Positives = 31/62 (50%) Frame = +3 Query: 432 LPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVRLAIIE 611 + + + L++E +RLN I KL + +G++ LLP + + D V LA+ E Sbjct: 12 IAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIYDED-EVLLALAE 70 Query: 612 YI 617 + Sbjct: 71 QL 72
>2AAA_HUMAN (P30153) Serine/threonine-protein phosphatase 2A 65 kDa regulatory| subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform) (Medium tumor antigen-associated 61 kDa protein) Length = 588 Score = 254 bits (650), Expect = 1e-67 Identities = 135/213 (63%), Positives = 166/213 (77%), Gaps = 4/213 (1%) Frame = +3 Query: 3 SVRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEP 182 SVRLLAVE C + +LL +D A ++P + ++DKSW VRYMVA++ EL +AVGPE Sbjct: 218 SVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWAVRYMVADKFTELQKAVGPEI 277 Query: 183 TRADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQ----LAIQHILPCVKELSSDSS 350 T+ DLVPA+ L++D EAEVR AA+ KV +FC LS + + ILPC+KEL SD++ Sbjct: 278 TKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENVIMSQILPCIKELVSDAN 337 Query: 351 QHVRSALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGID 530 QHV+SALASVIMG++P+LGKD TIE LLP+FL+ LKDE P+VRLNIIS LD VN+VIGI Sbjct: 338 QHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIR 397 Query: 531 LLSQSLLPAIVELAEDRHWRVRLAIIEYIPLLA 629 LSQSLLPAIVELAED WRVRLAIIEY+PLLA Sbjct: 398 QLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLA 430 Score = 69.3 bits (168), Expect = 9e-12 Identities = 50/199 (25%), Positives = 85/199 (42%) Frame = +3 Query: 6 VRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPT 185 VR AVE A+ P D AH +P++ + W A L+ +C Sbjct: 103 VRDKAVESLRAISHEHSPSDLEAHFVPLVKRLAGG-DWFTSRTSACGLFSVCYPRVSSAV 161 Query: 186 RADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRS 365 +A+L + L D+ VR AAA K+ +F ++L I+P L+SD VR Sbjct: 162 KAELRQYFRNLCSDDTPMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRL 221 Query: 366 ALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQS 545 + +A +L ++ ++P +D+ VR + K ++ + +G ++ Sbjct: 222 LAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWAVRYMVADKFTELQKAVGPEITKTD 281 Query: 546 LLPAIVELAEDRHWRVRLA 602 L+PA L +D VR A Sbjct: 282 LVPAFQNLMKDCEAEVRAA 300 Score = 68.9 bits (167), Expect = 1e-11 Identities = 49/208 (23%), Positives = 90/208 (43%) Frame = +3 Query: 6 VRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPT 185 VRL + + +++ + +LP IV ++D WRVR + + L +G E Sbjct: 379 VRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFF 438 Query: 186 RADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRS 365 L + L D+ +R AA + K + A I+P V +S D + R Sbjct: 439 DEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATIIPKVLAMSGDPNYLHRM 498 Query: 366 ALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQS 545 I ++ V G+D T + +LP L + D +VR N+ L ++ ++ L Sbjct: 499 TTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANVRFNVAKSLQKIGPILDNSTLQSE 558 Query: 546 LLPAIVELAEDRHWRVRLAIIEYIPLLA 629 + P + +L +D+ V+ E + +L+ Sbjct: 559 VKPILEKLTQDQDVDVKYFAQEALTVLS 586 Score = 63.2 bits (152), Expect = 6e-10 Identities = 41/178 (23%), Positives = 82/178 (46%), Gaps = 4/178 (2%) Frame = +3 Query: 96 NFSQDKSWRVRYMVANQLYELCEAVGPEPTRADLVPAYVRLLRDNEAEVRIAAAGKVTKF 275 N D + VR A++L E + + + +++++P + L D + VR+ A Sbjct: 171 NLCSDDTPMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNI 230 Query: 276 CRILSPQLAIQHILPCVKELSSDSSQHVRSALASVIMGMAPVLGKDATIEQLLPIFLSLL 455 ++L + ++P +++ + D S VR +A + +G + T L+P F +L+ Sbjct: 231 AQLLPQEDLEALVMPTLRQAAEDKSWAVRYMVADKFTELQKAVGPEITKTDLVPAFQNLM 290 Query: 456 KDEFPDVRLNIISKLDQVNQVIGID----LLSQSLLPAIVELAEDRHWRVRLAIIEYI 617 KD +VR K+ + + + D ++ +LP I EL D + V+ A+ I Sbjct: 291 KDCEAEVRAAASHKVKEFCENLSADCRENVIMSQILPCIKELVSDANQHVKSALASVI 348 Score = 60.1 bits (144), Expect = 5e-09 Identities = 45/202 (22%), Positives = 93/202 (46%) Frame = +3 Query: 24 EGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPTRADLVP 203 E C L ++ ILP I D + V+ +A+ + L +G + T L+P Sbjct: 307 EFCENLSADCRENVIMSQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLP 366 Query: 204 AYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRSALASVI 383 ++ L+D EVR+ + ++ + Q +LP + EL+ D+ VR A+ + Sbjct: 367 LFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYM 426 Query: 384 MGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIV 563 +A LG + E+L + ++ L D +R S L ++ + G + +++P ++ Sbjct: 427 PLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATIIPKVL 486 Query: 564 ELAEDRHWRVRLAIIEYIPLLA 629 ++ D ++ R+ + I +L+ Sbjct: 487 AMSGDPNYLHRMTTLFCINVLS 508 Score = 56.6 bits (135), Expect = 6e-08 Identities = 51/203 (25%), Positives = 85/203 (41%), Gaps = 1/203 (0%) Frame = +3 Query: 6 VRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPT 185 V L E L+ + V +LP + + + + VR L + P Sbjct: 64 VLLALAEQLGTFTTLVGGPEYVHCLLPPLESLATVEETVVRDKAVESLRAISHEHSPSDL 123 Query: 186 RADLVPAYVRLLRDNEAEVRIAAAGKVTK-FCRILSPQLAIQHILPCVKELSSDSSQHVR 362 A VP RL + R +A G + + R+ S A + + L SD + VR Sbjct: 124 EAHFVPLVKRLAGGDWFTSRTSACGLFSVCYPRVSSAVKA--ELRQYFRNLCSDDTPMVR 181 Query: 363 SALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQ 542 A AS + A VL D +++P+F +L DE VRL + + Q++ + L Sbjct: 182 RAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEA 241 Query: 543 SLLPAIVELAEDRHWRVRLAIIE 611 ++P + + AED+ W VR + + Sbjct: 242 LVMPTLRQAAEDKSWAVRYMVAD 264 Score = 30.4 bits (67), Expect = 4.5 Identities = 17/62 (27%), Positives = 31/62 (50%) Frame = +3 Query: 432 LPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVRLAIIE 611 + + + L++E +RLN I KL + +G++ LLP + + D V LA+ E Sbjct: 12 IAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIYDED-EVLLALAE 70 Query: 612 YI 617 + Sbjct: 71 QL 72
>2AAB_PIG (P54613) Serine/threonine-protein phosphatase 2A 65 kDa regulatory| subunit A beta isoform (PP2A, subunit A, PR65-beta isoform) (PP2A, subunit A, R1-beta isoform) (Fragment) Length = 602 Score = 246 bits (629), Expect = 3e-65 Identities = 132/213 (61%), Positives = 163/213 (76%), Gaps = 4/213 (1%) Frame = +3 Query: 3 SVRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEP 182 SVRLLAVE C ++ +LL D A ++P + ++DKSWRVRYMVA++ EL AVGP+ Sbjct: 232 SVRLLAVEACVSIAQLLSQDDLEALVMPTLRQAAEDKSWRVRYMVADKFSELQRAVGPKI 291 Query: 183 TRADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQ----LAIQHILPCVKELSSDSS 350 T DL+PA+ LL+D EAEVR AAA KV + C L + + + ILPC+KEL SD++ Sbjct: 292 TLNDLIPAFQNLLKDCEAEVRAAAAHKVKELCENLPIEGRETIIMNQILPCIKELVSDTN 351 Query: 351 QHVRSALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGID 530 QHV+SALASVIMG++ +LGK+ TIE LLP+FL+ LKDE P+VRLNIIS LD VN+VIGI Sbjct: 352 QHVKSALASVIMGLSTILGKENTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIR 411 Query: 531 LLSQSLLPAIVELAEDRHWRVRLAIIEYIPLLA 629 LSQSLLPAIVELAED WRVRLAIIEY+PLLA Sbjct: 412 QLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLA 444 Score = 77.0 bits (188), Expect = 4e-14 Identities = 51/208 (24%), Positives = 95/208 (45%) Frame = +3 Query: 6 VRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPT 185 VRL + + +++ + +LP IV ++D WRVR + + L +G E Sbjct: 393 VRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFF 452 Query: 186 RADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRS 365 L + L D+ +R AA + K + + A I+P V +++D + R Sbjct: 453 DEKLNSLCMAWLVDHVYAIREAATNNLMKLVQKFGTEWAQNTIVPKVLVMANDPNYLHRM 512 Query: 366 ALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQS 545 I ++ G++ T +Q+LPI L + D+ +VR N+ L ++ ++ D L + Sbjct: 513 TTLFCINVLSEACGQEITTKQMLPIVLKMAGDQVANVRFNVAKSLQKIGPILDTDALQEE 572 Query: 546 LLPAIVELAEDRHWRVRLAIIEYIPLLA 629 + P + +L +D V+ E I +LA Sbjct: 573 VKPVLQKLGQDEDMDVKYFAQEAISVLA 600 Score = 67.8 bits (164), Expect = 3e-11 Identities = 43/174 (24%), Positives = 83/174 (47%), Gaps = 4/174 (2%) Frame = +3 Query: 108 DKSWRVRYMVANQLYELCEAVGPEPTRADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRIL 287 D + VR A++L E + + + ++++VP + L D + VR+ A ++L Sbjct: 189 DDTPMVRRAAASKLGEFAKVLELDSVKSEIVPLFTNLASDEQDSVRLLAVEACVSIAQLL 248 Query: 288 SPQLAIQHILPCVKELSSDSSQHVRSALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEF 467 S ++P +++ + D S VR +A + +G T+ L+P F +LLKD Sbjct: 249 SQDDLEALVMPTLRQAAEDKSWRVRYMVADKFSELQRAVGPKITLNDLIPAFQNLLKDCE 308 Query: 468 PDVRLNIISKLDQVNQVIGID----LLSQSLLPAIVELAEDRHWRVRLAIIEYI 617 +VR K+ ++ + + I+ ++ +LP I EL D + V+ A+ I Sbjct: 309 AEVRAAAAHKVKELCENLPIEGRETIIMNQILPCIKELVSDTNQHVKSALASVI 362 Score = 65.9 bits (159), Expect = 1e-10 Identities = 48/199 (24%), Positives = 83/199 (41%) Frame = +3 Query: 6 VRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPT 185 VR AVE + + P AH +P++ + W A L+ +C Sbjct: 117 VRDKAVESLRQISQEHTPVALEAHFVPLVKRLASG-DWFTSRTSACGLFSVCYPRASNAV 175 Query: 186 RADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRS 365 +A++ + L D+ VR AAA K+ +F ++L I+P L+SD VR Sbjct: 176 KAEIRQHFRSLCSDDTPMVRRAAASKLGEFAKVLELDSVKSEIVPLFTNLASDEQDSVRL 235 Query: 366 ALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQS 545 + +A +L +D ++P +D+ VR + K ++ + +G + Sbjct: 236 LAVEACVSIAQLLSQDDLEALVMPTLRQAAEDKSWRVRYMVADKFSELQRAVGPKITLND 295 Query: 546 LLPAIVELAEDRHWRVRLA 602 L+PA L +D VR A Sbjct: 296 LIPAFQNLLKDCEAEVRAA 314 Score = 64.3 bits (155), Expect = 3e-10 Identities = 47/178 (26%), Positives = 79/178 (44%) Frame = +3 Query: 78 ILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPTRADLVPAYVRLLRDNEAEVRIAAA 257 +LP + + + + VR L ++ + P A VP RL + R +A Sbjct: 102 LLPPLESLATVEETVVRDKAVESLRQISQEHTPVALEAHFVPLVKRLASGDWFTSRTSAC 161 Query: 258 GKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRSALASVIMGMAPVLGKDATIEQLLP 437 G + C + I + L SD + VR A AS + A VL D+ +++P Sbjct: 162 G-LFSVCYPRASNAVKAEIRQHFRSLCSDDTPMVRRAAASKLGEFAKVLELDSVKSEIVP 220 Query: 438 IFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVRLAIIE 611 +F +L DE VRL + + Q++ D L ++P + + AED+ WRVR + + Sbjct: 221 LFTNLASDEQDSVRLLAVEACVSIAQLLSQDDLEALVMPTLRQAAEDKSWRVRYMVAD 278 Score = 62.0 bits (149), Expect = 1e-09 Identities = 44/184 (23%), Positives = 88/184 (47%) Frame = +3 Query: 78 ILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPTRADLVPAYVRLLRDNEAEVRIAAA 257 ILP I D + V+ +A+ + L +G E T L+P ++ L+D EVR+ Sbjct: 339 ILPCIKELVSDTNQHVKSALASVIMGLSTILGKENTIEHLLPLFLAQLKDECPEVRLNII 398 Query: 258 GKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRSALASVIMGMAPVLGKDATIEQLLP 437 + ++ + Q +LP + EL+ D+ VR A+ + +A LG + E+L Sbjct: 399 SNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNS 458 Query: 438 IFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVRLAIIEYI 617 + ++ L D +R + L ++ Q G + +++P ++ +A D ++ R+ + I Sbjct: 459 LCMAWLVDHVYAIREAATNNLMKLVQKFGTEWAQNTIVPKVLVMANDPNYLHRMTTLFCI 518 Query: 618 PLLA 629 +L+ Sbjct: 519 NVLS 522 Score = 31.6 bits (70), Expect = 2.0 Identities = 23/79 (29%), Positives = 37/79 (46%), Gaps = 2/79 (2%) Frame = +3 Query: 387 GMAPVLGKDATIEQLLPIFLSL--LKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAI 560 G PV + L PI + + L++E +RLN I KL + +G++ LLP + Sbjct: 9 GTGPVAAGGDGDDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRTELLPFL 68 Query: 561 VELAEDRHWRVRLAIIEYI 617 + D V LA+ E + Sbjct: 69 TDTIYDED-EVLLALAEQL 86
>2AAB_MOUSE (Q7TNP2) Serine/threonine-protein phosphatase 2A 65 kDa regulatory| subunit A beta isoform (PP2A, subunit A, PR65-beta isoform) (PP2A, subunit A, R1-beta isoform) Length = 601 Score = 245 bits (626), Expect = 7e-65 Identities = 133/213 (62%), Positives = 164/213 (76%), Gaps = 4/213 (1%) Frame = +3 Query: 3 SVRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEP 182 SVRLLAVE C ++ +LL +D A ++P + ++DKSWRVRYMVA++ EL +AVGP+ Sbjct: 231 SVRLLAVEACVSIAQLLSQEDLEALVIPTLRQAAEDKSWRVRYMVADKFSELQKAVGPKI 290 Query: 183 TRADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQ----LAIQHILPCVKELSSDSS 350 +DL+PA+ LLRD EAEVR AAA KV + C L + + + ILP +KEL SD+S Sbjct: 291 ALSDLIPAFQSLLRDCEAEVRAAAAHKVRELCENLPAEGRETVIMNQILPYIKELVSDTS 350 Query: 351 QHVRSALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGID 530 QHV+SALASVIMG++ VLGK+ TIE LLP+FL+ LKDE P+VRLNIIS LD VN+VIGI Sbjct: 351 QHVKSALASVIMGLSTVLGKENTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIR 410 Query: 531 LLSQSLLPAIVELAEDRHWRVRLAIIEYIPLLA 629 LSQSLLPAIVELAED WRVRLAIIEY+PLLA Sbjct: 411 QLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLA 443 Score = 76.3 bits (186), Expect = 7e-14 Identities = 51/208 (24%), Positives = 94/208 (45%) Frame = +3 Query: 6 VRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPT 185 VRL + + +++ + +LP IV ++D WRVR + + L +G E Sbjct: 392 VRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFF 451 Query: 186 RADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRS 365 L + L D+ +R AA + K + + A I+P V +++D + R Sbjct: 452 DEKLNSLCMAWLVDHVYAIREAATNNLMKLVQKFGTEWAQNTIVPKVLVMANDPNYLHRM 511 Query: 366 ALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQS 545 I ++ GK+ T +Q+LPI L + D+ +VR N+ L ++ ++ + L Sbjct: 512 TTLFCINALSEACGKEITTKQMLPIVLKMAGDQVANVRFNVAKSLQKIGPILDTNALQGE 571 Query: 546 LLPAIVELAEDRHWRVRLAIIEYIPLLA 629 + P + +L +D V+ E I +LA Sbjct: 572 VKPVLQKLGQDEDMDVKYFAQEAISVLA 599 Score = 62.8 bits (151), Expect = 8e-10 Identities = 45/184 (24%), Positives = 87/184 (47%) Frame = +3 Query: 78 ILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPTRADLVPAYVRLLRDNEAEVRIAAA 257 ILP I D S V+ +A+ + L +G E T L+P ++ L+D EVR+ Sbjct: 338 ILPYIKELVSDTSQHVKSALASVIMGLSTVLGKENTIEHLLPLFLAQLKDECPEVRLNII 397 Query: 258 GKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRSALASVIMGMAPVLGKDATIEQLLP 437 + ++ + Q +LP + EL+ D+ VR A+ + +A LG + E+L Sbjct: 398 SNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNS 457 Query: 438 IFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVRLAIIEYI 617 + ++ L D +R + L ++ Q G + +++P ++ +A D ++ R+ + I Sbjct: 458 LCMAWLVDHVYAIREAATNNLMKLVQKFGTEWAQNTIVPKVLVMANDPNYLHRMTTLFCI 517 Query: 618 PLLA 629 L+ Sbjct: 518 NALS 521 Score = 61.6 bits (148), Expect = 2e-09 Identities = 46/199 (23%), Positives = 82/199 (41%) Frame = +3 Query: 6 VRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPT 185 VR AVE + + P AH +P++ + W + A L+ +C Sbjct: 116 VRDKAVESLRQISQEHTPVALEAHFVPLVKRLASG-DWFMSRTSACGLFSVCYPRASNAV 174 Query: 186 RADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRS 365 +A++ + L D+ R AAA K+ +F ++L I+P L+SD VR Sbjct: 175 KAEIRQHFRSLCSDDTPMERRAAASKLGEFAKVLELDSVKTEIVPLFTNLASDEQDSVRL 234 Query: 366 ALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQS 545 + +A +L ++ ++P +D+ VR + K ++ + +G + Sbjct: 235 LAVEACVSIAQLLSQEDLEALVIPTLRQAAEDKSWRVRYMVADKFSELQKAVGPKIALSD 294 Query: 546 LLPAIVELAEDRHWRVRLA 602 L+PA L D VR A Sbjct: 295 LIPAFQSLLRDCEAEVRAA 313 Score = 60.5 bits (145), Expect = 4e-09 Identities = 39/168 (23%), Positives = 77/168 (45%), Gaps = 4/168 (2%) Frame = +3 Query: 126 RYMVANQLYELCEAVGPEPTRADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAI 305 R A++L E + + + + ++VP + L D + VR+ A ++LS + Sbjct: 194 RRAAASKLGEFAKVLELDSVKTEIVPLFTNLASDEQDSVRLLAVEACVSIAQLLSQEDLE 253 Query: 306 QHILPCVKELSSDSSQHVRSALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLN 485 ++P +++ + D S VR +A + +G + L+P F SLL+D +VR Sbjct: 254 ALVIPTLRQAAEDKSWRVRYMVADKFSELQKAVGPKIALSDLIPAFQSLLRDCEAEVRAA 313 Query: 486 IISKLDQVNQVIGID----LLSQSLLPAIVELAEDRHWRVRLAIIEYI 617 K+ ++ + + + ++ +LP I EL D V+ A+ I Sbjct: 314 AAHKVRELCENLPAEGRETVIMNQILPYIKELVSDTSQHVKSALASVI 361 Score = 59.7 bits (143), Expect = 7e-09 Identities = 45/178 (25%), Positives = 78/178 (43%) Frame = +3 Query: 78 ILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPTRADLVPAYVRLLRDNEAEVRIAAA 257 +LP + + + + VR L ++ + P A VP RL + R +A Sbjct: 101 LLPPLESLATVEETVVRDKAVESLRQISQEHTPVALEAHFVPLVKRLASGDWFMSRTSAC 160 Query: 258 GKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRSALASVIMGMAPVLGKDATIEQLLP 437 G + C + I + L SD + R A AS + A VL D+ +++P Sbjct: 161 G-LFSVCYPRASNAVKAEIRQHFRSLCSDDTPMERRAAASKLGEFAKVLELDSVKTEIVP 219 Query: 438 IFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVRLAIIE 611 +F +L DE VRL + + Q++ + L ++P + + AED+ WRVR + + Sbjct: 220 LFTNLASDEQDSVRLLAVEACVSIAQLLSQEDLEALVIPTLRQAAEDKSWRVRYMVAD 277 Score = 30.0 bits (66), Expect = 5.9 Identities = 17/62 (27%), Positives = 31/62 (50%) Frame = +3 Query: 432 LPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVRLAIIE 611 + + + L++E +RLN I KL + +G++ LLP + + D V LA+ E Sbjct: 25 IAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRTELLPFLTDTIYDED-EVLLALAE 83 Query: 612 YI 617 + Sbjct: 84 QL 85
>2AAB_RAT (Q4QQT4) Serine/threonine-protein phosphatase 2A 65 kDa regulatory| subunit A beta isoform (PP2A, subunit A, PR65-beta isoform) (PP2A, subunit A, R1-beta isoform) Length = 601 Score = 243 bits (621), Expect = 3e-64 Identities = 132/213 (61%), Positives = 163/213 (76%), Gaps = 4/213 (1%) Frame = +3 Query: 3 SVRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEP 182 SVRLLAVE C ++ +LL D A ++P + ++DKSWRVRYMVA++ EL +AVGP+ Sbjct: 231 SVRLLAVEACVSIAQLLSQDDLEALVMPTLRQAAEDKSWRVRYMVADKFSELQKAVGPKI 290 Query: 183 TRADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQ----LAIQHILPCVKELSSDSS 350 +DL+PA+ LLRD EAEVR AAA KV + C L + + + ILP +KEL SD++ Sbjct: 291 ALSDLIPAFQSLLRDCEAEVRAAAAHKVRELCENLPTEGRETVIMNQILPYIKELVSDTN 350 Query: 351 QHVRSALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGID 530 QHV+SALASVIMG++ VLGK+ TIE LLP+FL+ LKDE P+VRLNIIS LD VN+VIGI Sbjct: 351 QHVKSALASVIMGLSTVLGKENTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIR 410 Query: 531 LLSQSLLPAIVELAEDRHWRVRLAIIEYIPLLA 629 LSQSLLPAIVELAED WRVRLAIIEY+PLLA Sbjct: 411 QLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLA 443 Score = 76.3 bits (186), Expect = 7e-14 Identities = 51/208 (24%), Positives = 94/208 (45%) Frame = +3 Query: 6 VRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPT 185 VRL + + +++ + +LP IV ++D WRVR + + L +G E Sbjct: 392 VRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFF 451 Query: 186 RADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRS 365 L + L D+ +R AA + K + + A I+P V +++D + R Sbjct: 452 DEKLNSLCMAWLVDHVYAIREAATNNLMKLVQKFGTEWAQNTIVPKVLVMANDPNYLHRM 511 Query: 366 ALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQS 545 I ++ GK+ T +Q+LPI L + D+ +VR N+ L ++ ++ + L Sbjct: 512 TTLFCINALSEACGKEITTKQMLPIVLKMAGDQVANVRFNVAKSLQKIGPILDTNALQGE 571 Query: 546 LLPAIVELAEDRHWRVRLAIIEYIPLLA 629 + P + +L +D V+ E I +LA Sbjct: 572 VKPVLQKLGQDEDMDVKYFAQEAISVLA 599 Score = 65.1 bits (157), Expect = 2e-10 Identities = 48/199 (24%), Positives = 82/199 (41%) Frame = +3 Query: 6 VRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPT 185 VR AVE + + P AH +P++ + W A L+ +C Sbjct: 116 VRDKAVESLRQISQEHTPVALEAHFVPLVKRLASG-DWFTSRTSACGLFSVCYPRASNAV 174 Query: 186 RADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRS 365 +A++ + L D+ VR AAA K+ +F ++L I+P L+SD VR Sbjct: 175 KAEIRQHFRSLCSDDTPMVRRAAASKLGEFAKVLELDSVKTEIVPLFTNLASDEQDSVRL 234 Query: 366 ALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQS 545 + +A +L +D ++P +D+ VR + K ++ + +G + Sbjct: 235 LAVEACVSIAQLLSQDDLEALVMPTLRQAAEDKSWRVRYMVADKFSELQKAVGPKIALSD 294 Query: 546 LLPAIVELAEDRHWRVRLA 602 L+PA L D VR A Sbjct: 295 LIPAFQSLLRDCEAEVRAA 313 Score = 63.9 bits (154), Expect = 4e-10 Identities = 47/178 (26%), Positives = 79/178 (44%) Frame = +3 Query: 78 ILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPTRADLVPAYVRLLRDNEAEVRIAAA 257 +LP + + + + VR L ++ + P A VP RL + R +A Sbjct: 101 LLPPLESLATVEETVVRDKAVESLRQISQEHTPVALEAHFVPLVKRLASGDWFTSRTSAC 160 Query: 258 GKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRSALASVIMGMAPVLGKDATIEQLLP 437 G + C + I + L SD + VR A AS + A VL D+ +++P Sbjct: 161 G-LFSVCYPRASNAVKAEIRQHFRSLCSDDTPMVRRAAASKLGEFAKVLELDSVKTEIVP 219 Query: 438 IFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVRLAIIE 611 +F +L DE VRL + + Q++ D L ++P + + AED+ WRVR + + Sbjct: 220 LFTNLASDEQDSVRLLAVEACVSIAQLLSQDDLEALVMPTLRQAAEDKSWRVRYMVAD 277 Score = 62.4 bits (150), Expect = 1e-09 Identities = 41/174 (23%), Positives = 80/174 (45%), Gaps = 4/174 (2%) Frame = +3 Query: 108 DKSWRVRYMVANQLYELCEAVGPEPTRADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRIL 287 D + VR A++L E + + + + ++VP + L D + VR+ A ++L Sbjct: 188 DDTPMVRRAAASKLGEFAKVLELDSVKTEIVPLFTNLASDEQDSVRLLAVEACVSIAQLL 247 Query: 288 SPQLAIQHILPCVKELSSDSSQHVRSALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEF 467 S ++P +++ + D S VR +A + +G + L+P F SLL+D Sbjct: 248 SQDDLEALVMPTLRQAAEDKSWRVRYMVADKFSELQKAVGPKIALSDLIPAFQSLLRDCE 307 Query: 468 PDVRLNIISKLDQVNQVIGID----LLSQSLLPAIVELAEDRHWRVRLAIIEYI 617 +VR K+ ++ + + + ++ +LP I EL D + V+ A+ I Sbjct: 308 AEVRAAAAHKVRELCENLPTEGRETVIMNQILPYIKELVSDTNQHVKSALASVI 361 Score = 61.6 bits (148), Expect = 2e-09 Identities = 44/184 (23%), Positives = 87/184 (47%) Frame = +3 Query: 78 ILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPTRADLVPAYVRLLRDNEAEVRIAAA 257 ILP I D + V+ +A+ + L +G E T L+P ++ L+D EVR+ Sbjct: 338 ILPYIKELVSDTNQHVKSALASVIMGLSTVLGKENTIEHLLPLFLAQLKDECPEVRLNII 397 Query: 258 GKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRSALASVIMGMAPVLGKDATIEQLLP 437 + ++ + Q +LP + EL+ D+ VR A+ + +A LG + E+L Sbjct: 398 SNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNS 457 Query: 438 IFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVRLAIIEYI 617 + ++ L D +R + L ++ Q G + +++P ++ +A D ++ R+ + I Sbjct: 458 LCMAWLVDHVYAIREAATNNLMKLVQKFGTEWAQNTIVPKVLVMANDPNYLHRMTTLFCI 517 Query: 618 PLLA 629 L+ Sbjct: 518 NALS 521 Score = 30.0 bits (66), Expect = 5.9 Identities = 17/62 (27%), Positives = 31/62 (50%) Frame = +3 Query: 432 LPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVRLAIIE 611 + + + L++E +RLN I KL + +G++ LLP + + D V LA+ E Sbjct: 25 IAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRTELLPFLTDTIYDED-EVLLALAE 83 Query: 612 YI 617 + Sbjct: 84 QL 85
>2AAB_HUMAN (P30154) Serine/threonine-protein phosphatase 2A 65 kDa regulatory| subunit A beta isoform (PP2A, subunit A, PR65-beta isoform) (PP2A, subunit A, R1-beta isoform) Length = 601 Score = 237 bits (604), Expect = 2e-62 Identities = 129/213 (60%), Positives = 161/213 (75%), Gaps = 4/213 (1%) Frame = +3 Query: 3 SVRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEP 182 SVRLLAVE C ++ +LL D ++P + ++DKSWRVRYMVA++ EL +A+GP+ Sbjct: 231 SVRLLAVEACVSIAQLLSQDDLETLVMPTLRQAAEDKSWRVRYMVADRFSELQKAMGPKI 290 Query: 183 TRADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQ----LAIQHILPCVKELSSDSS 350 T DL+PA+ LL+D EAEVR AAA KV + L + + + ILP +KEL SD++ Sbjct: 291 TLNDLIPAFQNLLKDCEAEVRAAAAHKVKELGENLPIEDRETIIMNQILPYIKELVSDTN 350 Query: 351 QHVRSALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGID 530 QHV+SALASVIMG++ +LGK+ TIE LLP+FL+ LKDE PDVRLNIIS LD VN+VIGI Sbjct: 351 QHVKSALASVIMGLSTILGKENTIEHLLPLFLAQLKDECPDVRLNIISNLDCVNEVIGIR 410 Query: 531 LLSQSLLPAIVELAEDRHWRVRLAIIEYIPLLA 629 LSQSLLPAIVELAED WRVRLAIIEY+PLLA Sbjct: 411 QLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLA 443 Score = 74.7 bits (182), Expect = 2e-13 Identities = 50/208 (24%), Positives = 94/208 (45%) Frame = +3 Query: 6 VRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPT 185 VRL + + +++ + +LP IV ++D WRVR + + L +G E Sbjct: 392 VRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFF 451 Query: 186 RADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRS 365 L + L D+ +R AA + K + + A I+P V +++D + R Sbjct: 452 DEKLNSLCMAWLVDHVYAIREAATNNLMKLVQKFGTEWAQNTIVPKVLVMANDPNYLHRM 511 Query: 366 ALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQS 545 I ++ G++ T +Q+LPI L + D+ +VR N+ L ++ ++ + L Sbjct: 512 TTLFCINALSEACGQEITTKQMLPIVLKMAGDQVANVRFNVAKSLQKIGPILDTNALQGE 571 Query: 546 LLPAIVELAEDRHWRVRLAIIEYIPLLA 629 + P + +L +D V+ E I +LA Sbjct: 572 VKPVLQKLGQDEDMDVKYFAQEAISVLA 599 Score = 68.2 bits (165), Expect = 2e-11 Identities = 43/174 (24%), Positives = 83/174 (47%), Gaps = 4/174 (2%) Frame = +3 Query: 108 DKSWRVRYMVANQLYELCEAVGPEPTRADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRIL 287 D + VR A++L E + + + ++++VP + L D + VR+ A ++L Sbjct: 188 DDTPMVRRAAASKLGEFAKVLELDSVKSEIVPLFTSLASDEQDSVRLLAVEACVSIAQLL 247 Query: 288 SPQLAIQHILPCVKELSSDSSQHVRSALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEF 467 S ++P +++ + D S VR +A + +G T+ L+P F +LLKD Sbjct: 248 SQDDLETLVMPTLRQAAEDKSWRVRYMVADRFSELQKAMGPKITLNDLIPAFQNLLKDCE 307 Query: 468 PDVRLNIISKLDQVNQVIGID----LLSQSLLPAIVELAEDRHWRVRLAIIEYI 617 +VR K+ ++ + + I+ ++ +LP I EL D + V+ A+ I Sbjct: 308 AEVRAAAAHKVKELGENLPIEDRETIIMNQILPYIKELVSDTNQHVKSALASVI 361 Score = 64.7 bits (156), Expect = 2e-10 Identities = 48/178 (26%), Positives = 78/178 (43%) Frame = +3 Query: 78 ILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPTRADLVPAYVRLLRDNEAEVRIAAA 257 +LP + N + + VR L ++ + P A VP RL + R +A Sbjct: 101 LLPPLENLATVEETVVRDKAVESLRQISQEHTPVALEAYFVPLVKRLASGDWFTSRTSAC 160 Query: 258 GKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRSALASVIMGMAPVLGKDATIEQLLP 437 G + C + + L SD + VR A AS + A VL D+ +++P Sbjct: 161 G-LFSVCYPRASNAVKAETRQQFRSLCSDDTPMVRRAAASKLGEFAKVLELDSVKSEIVP 219 Query: 438 IFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVRLAIIE 611 +F SL DE VRL + + Q++ D L ++P + + AED+ WRVR + + Sbjct: 220 LFTSLASDEQDSVRLLAVEACVSIAQLLSQDDLETLVMPTLRQAAEDKSWRVRYMVAD 277 Score = 62.0 bits (149), Expect = 1e-09 Identities = 50/212 (23%), Positives = 97/212 (45%), Gaps = 4/212 (1%) Frame = +3 Query: 6 VRLLAVEGCAALGKLLEPQD----CVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVG 173 VR A LG+ L +D + ILP I D + V+ +A+ + L +G Sbjct: 310 VRAAAAHKVKELGENLPIEDRETIIMNQILPYIKELVSDTNQHVKSALASVIMGLSTILG 369 Query: 174 PEPTRADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQ 353 E T L+P ++ L+D +VR+ + ++ + Q +LP + EL+ D+ Sbjct: 370 KENTIEHLLPLFLAQLKDECPDVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKW 429 Query: 354 HVRSALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDL 533 VR A+ + +A LG + E+L + ++ L D +R + L ++ Q G + Sbjct: 430 RVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATNNLMKLVQKFGTEW 489 Query: 534 LSQSLLPAIVELAEDRHWRVRLAIIEYIPLLA 629 +++P ++ +A D ++ R+ + I L+ Sbjct: 490 AQNTIVPKVLVMANDPNYLHRMTTLFCINALS 521 Score = 60.8 bits (146), Expect = 3e-09 Identities = 46/199 (23%), Positives = 82/199 (41%) Frame = +3 Query: 6 VRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPT 185 VR AVE + + P A+ +P++ + W A L+ +C Sbjct: 116 VRDKAVESLRQISQEHTPVALEAYFVPLVKRLASG-DWFTSRTSACGLFSVCYPRASNAV 174 Query: 186 RADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRS 365 +A+ + L D+ VR AAA K+ +F ++L I+P L+SD VR Sbjct: 175 KAETRQQFRSLCSDDTPMVRRAAASKLGEFAKVLELDSVKSEIVPLFTSLASDEQDSVRL 234 Query: 366 ALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQS 545 + +A +L +D ++P +D+ VR + + ++ + +G + Sbjct: 235 LAVEACVSIAQLLSQDDLETLVMPTLRQAAEDKSWRVRYMVADRFSELQKAMGPKITLND 294 Query: 546 LLPAIVELAEDRHWRVRLA 602 L+PA L +D VR A Sbjct: 295 LIPAFQNLLKDCEAEVRAA 313 Score = 30.4 bits (67), Expect = 4.5 Identities = 17/62 (27%), Positives = 31/62 (50%) Frame = +3 Query: 432 LPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVRLAIIE 611 + + + L++E +RLN I KL + +G++ LLP + + D V LA+ E Sbjct: 25 IAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIYDED-EVLLALAE 83 Query: 612 YI 617 + Sbjct: 84 QL 85
>2AAA_DROME (P36179) Serine/threonine-protein phosphatase PP2A 65 kDa| regulatory subunit (Protein phosphatase PP2A regulatory subunit A) (PR65) Length = 590 Score = 236 bits (603), Expect = 3e-62 Identities = 133/214 (62%), Positives = 157/214 (73%), Gaps = 5/214 (2%) Frame = +3 Query: 3 SVRLLAVEGCAALGKLLEPQDCVAH-ILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPE 179 SVRLLAVE C +LL PQD V H +LP + + D SWRVRYMVA + +L +AVGPE Sbjct: 220 SVRLLAVEACVTSAQLL-PQDDVEHLVLPTLRQCASDSSWRVRYMVAEKFVDLQKAVGPE 278 Query: 180 PTRADLVPAYVRLLRDNEAEVRIAAAGKVTKFC----RILSPQLAIQHILPCVKELSSDS 347 TR DLVPA+ LL+D EAEVR A A KV FC ++ Q+ + ILP V++L SD Sbjct: 279 ITRVDLVPAFQYLLKDAEAEVRAAVATKVKDFCANLDKVNQVQIILSSILPYVRDLVSDP 338 Query: 348 SQHVRSALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGI 527 + HV+SALASVIMG++P+LG T+EQLLP+FL LKDE P+VRLNIIS LD VN VIGI Sbjct: 339 NPHVKSALASVIMGLSPMLGAYQTVEQLLPLFLIQLKDECPEVRLNIISNLDCVNDVIGI 398 Query: 528 DLLSQSLLPAIVELAEDRHWRVRLAIIEYIPLLA 629 LSQSLLPAIVELAED WRVRLAIIEY+P LA Sbjct: 399 QQLSQSLLPAIVELAEDSKWRVRLAIIEYMPALA 432 Score = 85.5 bits (210), Expect = 1e-16 Identities = 58/179 (32%), Positives = 98/179 (54%), Gaps = 8/179 (4%) Frame = +3 Query: 105 QDKSWRVRYMVANQLYELCEAVGPEPTRADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRI 284 QD++ VR AN+L E + V E ++DL+P +V+L +D++ VR+ A ++ Sbjct: 176 QDETPMVRRAAANKLGEFAKVVETEYLKSDLIPNFVQLAQDDQDSVRLLAVEACVTSAQL 235 Query: 285 LSPQLAIQH-ILPCVKELSSDSSQHVRSALASVIMGMAPVLGKDATIEQLLPIFLSLLKD 461 L PQ ++H +LP +++ +SDSS VR +A + + +G + T L+P F LLKD Sbjct: 236 L-PQDDVEHLVLPTLRQCASDSSWRVRYMVAEKFVDLQKAVGPEITRVDLVPAFQYLLKD 294 Query: 462 EFPDVRLNIISK-------LDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVRLAIIEYI 617 +VR + +K LD+VNQV ++ S+LP + +L D + V+ A+ I Sbjct: 295 AEAEVRAAVATKVKDFCANLDKVNQV---QIILSSILPYVRDLVSDPNPHVKSALASVI 350 Score = 67.4 bits (163), Expect = 3e-11 Identities = 46/200 (23%), Positives = 97/200 (48%) Frame = +3 Query: 30 CAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPTRADLVPAY 209 CA L K+ + Q ++ ILP + + D + V+ +A+ + L +G T L+P + Sbjct: 311 CANLDKVNQVQIILSSILPYVRDLVSDPNPHVKSALASVIMGLSPMLGAYQTVEQLLPLF 370 Query: 210 VRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRSALASVIMG 389 + L+D EVR+ + ++ Q Q +LP + EL+ DS VR A+ + Sbjct: 371 LIQLKDECPEVRLNIISNLDCVNDVIGIQQLSQSLLPAIVELAEDSKWRVRLAIIEYMPA 430 Query: 390 MAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVEL 569 +A LG++ ++L + + L D +R + ++ + G Q+++P I+ + Sbjct: 431 LAGQLGQEFFDQKLRGLCMGWLNDHVYAIREAATLNMKKLVEQFGAPWAEQAIIPMILVM 490 Query: 570 AEDRHWRVRLAIIEYIPLLA 629 + ++++ R+ + + +LA Sbjct: 491 SRNKNYLHRMTCLFCLNVLA 510 Score = 64.7 bits (156), Expect = 2e-10 Identities = 47/191 (24%), Positives = 80/191 (41%) Frame = +3 Query: 6 VRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPT 185 VRL + + ++ Q +LP IV ++D WRVR + + L +G E Sbjct: 381 VRLNIISNLDCVNDVIGIQQLSQSLLPAIVELAEDSKWRVRLAIIEYMPALAGQLGQEFF 440 Query: 186 RADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRS 365 L + L D+ +R AA + K A Q I+P + +S + + R Sbjct: 441 DQKLRGLCMGWLNDHVYAIREAATLNMKKLVEQFGAPWAEQAIIPMILVMSRNKNYLHRM 500 Query: 366 ALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQS 545 + +A V G D T + LLP L L D +VR N+ L +++ + ++ Sbjct: 501 TCLFCLNVLAEVCGTDITTKLLLPTVLLLAADPVANVRFNVAKTLQKISPFLEASVIDAQ 560 Query: 546 LLPAIVELAED 578 + P + +L D Sbjct: 561 VKPTLDKLNTD 571 Score = 50.1 bits (118), Expect = 6e-06 Identities = 49/202 (24%), Positives = 84/202 (41%) Frame = +3 Query: 6 VRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPT 185 +RL +++ + + L + + ++P + D+ V +A+QL VG Sbjct: 28 LRLNSIKKLSTIALALGEERTRSELIPFLTETIYDED-EVLLALADQLGNFTSLVGGPEF 86 Query: 186 RADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRS 365 L+P L E VR A + S Q H++P ++ L S R+ Sbjct: 87 AMYLIPPLESLATVEETVVRDKAVESLRTVAAEHSAQDLEIHVVPTLQRLVSGDWFTSRT 146 Query: 366 ALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQS 545 + + P + + E L F L +DE P VR +KL + +V+ + L Sbjct: 147 SACGLFSVCYPRVTQPVKAE-LRANFRKLCQDETPMVRRAAANKLGEFAKVVETEYLKSD 205 Query: 546 LLPAIVELAEDRHWRVRLAIIE 611 L+P V+LA+D VRL +E Sbjct: 206 LIPNFVQLAQDDQDSVRLLAVE 227 Score = 48.1 bits (113), Expect = 2e-05 Identities = 43/165 (26%), Positives = 73/165 (44%), Gaps = 5/165 (3%) Frame = +3 Query: 132 MVANQLYELCEAVGPEPTRADL----VPAYVRLLRDNEAEVRIAAAGKVTK-FCRILSPQ 296 +V ++ E V E + DL VP RL+ + R +A G + + R+ P Sbjct: 104 VVRDKAVESLRTVAAEHSAQDLEIHVVPTLQRLVSGDWFTSRTSACGLFSVCYPRVTQPV 163 Query: 297 LAIQHILPCVKELSSDSSQHVRSALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDV 476 A + ++L D + VR A A+ + A V+ + L+P F+ L +D+ V Sbjct: 164 KA--ELRANFRKLCQDETPMVRRAAANKLGEFAKVVETEYLKSDLIPNFVQLAQDDQDSV 221 Query: 477 RLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVRLAIIE 611 RL + Q++ D + +LP + + A D WRVR + E Sbjct: 222 RLLAVEACVTSAQLLPQDDVEHLVLPTLRQCASDSSWRVRYMVAE 266 Score = 41.6 bits (96), Expect = 0.002 Identities = 29/106 (27%), Positives = 49/106 (46%) Frame = +3 Query: 78 ILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPTRADLVPAYVRLLRDNEAEVRIAAA 257 I+P+I+ S++K++ R L L E G + T L+P + L D A VR A Sbjct: 483 IIPMILVMSRNKNYLHRMTCLFCLNVLAEVCGTDITTKLLLPTVLLLAADPVANVRFNVA 542 Query: 258 GKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRSALASVIMGMA 395 + K L + + P + +L++D+ V+ A I G+A Sbjct: 543 KTLQKISPFLEASVIDAQVKPTLDKLNTDTDVDVKHFAAQAIAGIA 588
>2AAA_SCHPO (Q9UT08) Protein phosphatase PP2A regulatory subunit A (PR65)| (Protein phosphatase 2A 65 kDa regulatory subunit) Length = 590 Score = 209 bits (531), Expect = 7e-54 Identities = 109/210 (51%), Positives = 150/210 (71%), Gaps = 1/210 (0%) Frame = +3 Query: 3 SVRLLAVEGCAALGKLLEPQDCVAH-ILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPE 179 SVRLL+ + +L ++L+ + H +L + +F D SWR RYMVA +L + VGP Sbjct: 220 SVRLLSFDIMVSLAEVLKSDSEIRHYLLQPLRSFVSDSSWRTRYMVAANFVKLAKVVGPS 279 Query: 180 PTRADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHV 359 + +L+ +V L++D E EVR A A ++ FC +L ++ ++ I+P ++EL +D +QHV Sbjct: 280 LIKDELIKPFVLLMKDTEQEVRRAIATQIPGFCELLDKRIVLEEIIPVIQELINDPAQHV 339 Query: 360 RSALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLS 539 R+AL I +AP LGK+ T E LLP+FL LLKDE P+VRLNIISKL+ VN+V+GI+LLS Sbjct: 340 RAALGMNIGALAPQLGKEKTTEYLLPMFLELLKDENPEVRLNIISKLEVVNKVVGIELLS 399 Query: 540 QSLLPAIVELAEDRHWRVRLAIIEYIPLLA 629 QSLLPAIV LAED+ WRVRLAII+YIPLLA Sbjct: 400 QSLLPAIVTLAEDKQWRVRLAIIDYIPLLA 429 Score = 77.4 bits (189), Expect = 3e-14 Identities = 50/198 (25%), Positives = 97/198 (48%), Gaps = 4/198 (2%) Frame = +3 Query: 45 KLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPTRADLVPAYVRLLR 224 +LL+ + + I+PVI D + VR + + L +G E T L+P ++ LL+ Sbjct: 313 ELLDKRIVLEEIIPVIQELINDPAQHVRAALGMNIGALAPQLGKEKTTEYLLPMFLELLK 372 Query: 225 DNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRSALASVIMGMAPVL 404 D EVR+ K+ +++ +L Q +LP + L+ D VR A+ I +A L Sbjct: 373 DENPEVRLNIISKLEVVNKVVGIELLSQSLLPAIVTLAEDKQWRVRLAIIDYIPLLAQQL 432 Query: 405 GKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRH 584 G + E++ + +S L+D +R I L ++ ++ G++ +++++P + + + Sbjct: 433 GVEFFNEKMGNLCMSWLEDHVYSIREAAIKNLRKLTEIFGLEWATETIIPKFLAMRSHPN 492 Query: 585 WRVRL----AIIEYIPLL 626 + R+ AI E P L Sbjct: 493 YLYRMTTIFAISEIAPAL 510 Score = 69.3 bits (168), Expect = 9e-12 Identities = 46/195 (23%), Positives = 86/195 (44%), Gaps = 4/195 (2%) Frame = +3 Query: 6 VRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPT 185 VRL + + K++ + +LP IV ++DK WRVR + + + L + +G E Sbjct: 378 VRLNIISKLEVVNKVVGIELLSQSLLPAIVTLAEDKQWRVRLAIIDYIPLLAQQLGVEFF 437 Query: 186 RADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRS 365 + + L D+ +R AA + K I + A + I+P + S + R Sbjct: 438 NEKMGNLCMSWLEDHVYSIREAAIKNLRKLTEIFGLEWATETIIPKFLAMRSHPNYLYRM 497 Query: 366 ALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGI----DL 533 I +AP L + +Q+LP L+ D P++R N+ + + V+ + Sbjct: 498 TTIFAISEIAPALNAEVIEKQILPTLEQLVNDPIPNIRFNVAKAFEVLKPVLAAGGDSTV 557 Query: 534 LSQSLLPAIVELAED 578 Q ++P + +L +D Sbjct: 558 YEQQIIPLLEQLTKD 572 Score = 41.6 bits (96), Expect = 0.002 Identities = 51/239 (21%), Positives = 85/239 (35%), Gaps = 40/239 (16%) Frame = +3 Query: 9 RLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPTR 188 RL A+E + + L P+ ++P + D+ V +A+QL + VG Sbjct: 28 RLNALERLSTIALALGPERTRDELIPFLDESIDDED-EVLSALADQLGNFVDYVGGPEYA 86 Query: 189 ADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSS--------- 341 L+ L E VR A + K C LS + Q+ +P V+ LS+ Sbjct: 87 HVLLSPLENLAATEETVVRDKAVDSLNKVCICLSQEQLEQYFVPLVQRLSTAEWFTSRAS 146 Query: 342 ------------------------------DSSQHVRSALASVIMGMAPVLGKDATIEQL 431 D + VR A+ ++ K I++ Sbjct: 147 SAGLYCAAYSQSENPAVKVSLRQSFSHLCHDEAPMVRRPAATNCAKFVFLVTKQEAIDEF 206 Query: 432 LPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDL-LSQSLLPAIVELAEDRHWRVRLAI 605 +P+F SL D+ VRL + + +V+ D + LL + D WR R + Sbjct: 207 IPLFNSLSNDDQDSVRLLSFDIMVSLAEVLKSDSEIRHYLLQPLRSFVSDSSWRTRYMV 265 Score = 32.3 bits (72), Expect = 1.2 Identities = 34/172 (19%), Positives = 61/172 (35%), Gaps = 2/172 (1%) Frame = +3 Query: 3 SVRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEP 182 S+R A++ L ++ + I+P + ++ R + E+ A+ E Sbjct: 455 SIREAAIKNLRKLTEIFGLEWATETIIPKFLAMRSHPNYLYRMTTIFAISEIAPALNAEV 514 Query: 183 TRADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVR 362 ++P +L+ D +R V K +L P LA Sbjct: 515 IEKQILPTLEQLVNDPIPNIRF----NVAKAFEVLKPVLA-------------------- 550 Query: 363 SALASVIMGMAPVLGKDATI--EQLLPIFLSLLKDEFPDVRLNIISKLDQVN 512 G D+T+ +Q++P+ L KD PDV+ L+Q N Sbjct: 551 -------------AGGDSTVYEQQIIPLLEQLTKDNDPDVQYFATQALEQTN 589
>2AAA_CAEEL (Q09543) Probable serine/threonine-protein phosphatase PP2A| regulatory subunit (Protein phosphatase PP2A regulatory subunit A) Length = 590 Score = 192 bits (489), Expect = 5e-49 Identities = 106/213 (49%), Positives = 140/213 (65%), Gaps = 4/213 (1%) Frame = +3 Query: 3 SVRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEP 182 SVRLL VE A G LL+ + I P+++ DKSWRVRYMVA +L E+ +G + Sbjct: 221 SVRLLTVESAIAFGTLLDKANKKKLIEPILIELFDDKSWRVRYMVAEKLIEIQNVLGEDM 280 Query: 183 TRADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQ----LAIQHILPCVKELSSDSS 350 LV Y LL+D E EVR AA ++ +F L + +L KEL +D + Sbjct: 281 DTTHLVNMYTNLLKDPEGEVRCAATQRLQEFALNLPEDKRQNIICNSLLNVAKELVTDGN 340 Query: 351 QHVRSALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGID 530 Q V+S LA VIMG+AP++GK+ T+ +LLPI++ LL D+ P+VRLNIIS LD+VN+VIG Sbjct: 341 QLVKSELAGVIMGLAPLIGKEQTVSELLPIYMQLLNDQTPEVRLNIISSLDKVNEVIGAA 400 Query: 531 LLSQSLLPAIVELAEDRHWRVRLAIIEYIPLLA 629 LS SLLPAIV LAED WRVRLAI++++PLLA Sbjct: 401 QLSTSLLPAIVGLAEDGKWRVRLAIVQFMPLLA 433 Score = 70.9 bits (172), Expect = 3e-12 Identities = 43/197 (21%), Positives = 94/197 (47%) Frame = +3 Query: 6 VRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPT 185 VRL + + +++ +LP IV ++D WRVR + + L +G E Sbjct: 382 VRLNIISSLDKVNEVIGAAQLSTSLLPAIVGLAEDGKWRVRLAIVQFMPLLASQLGQEFF 441 Query: 186 RADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRS 365 L+P + L D+ +R A+ + + + Q A +I+P +++L D++ R Sbjct: 442 DEKLLPLCLNWLTDHVFSIREASTLIMKELTQKFGGQWASTNIVPKMQKLQKDTNYLQRM 501 Query: 366 ALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQS 545 + ++ + ++ +++++PI L++D+ P+VR N L ++ + + L+ Sbjct: 502 TCLFCLNTLSEAMTQEQILKEIMPIVKDLVEDDVPNVRFNAAKSLKRIGKNLTPSTLTSE 561 Query: 546 LLPAIVELAEDRHWRVR 596 + P + +L +D + VR Sbjct: 562 VKPLLEKLGKDSDFDVR 578 Score = 67.8 bits (164), Expect = 3e-11 Identities = 52/203 (25%), Positives = 94/203 (46%), Gaps = 10/203 (4%) Frame = +3 Query: 30 CAALGKLLE-----PQDCVAHI-----LPVIVNFSQDKSWRVRYMVANQLYELCEAVGPE 179 CAA +L E P+D +I L V D + V+ +A + L +G E Sbjct: 302 CAATQRLQEFALNLPEDKRQNIICNSLLNVAKELVTDGNQLVKSELAGVIMGLAPLIGKE 361 Query: 180 PTRADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHV 359 T ++L+P Y++LL D EVR+ + K ++ +LP + L+ D V Sbjct: 362 QTVSELLPIYMQLLNDQTPEVRLNIISSLDKVNEVIGAAQLSTSLLPAIVGLAEDGKWRV 421 Query: 360 RSALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLS 539 R A+ + +A LG++ E+LLP+ L+ L D +R + ++ Q G S Sbjct: 422 RLAIVQFMPLLASQLGQEFFDEKLLPLCLNWLTDHVFSIREASTLIMKELTQKFGGQWAS 481 Query: 540 QSLLPAIVELAEDRHWRVRLAII 608 +++P + +L +D ++ R+ + Sbjct: 482 TNIVPKMQKLQKDTNYLQRMTCL 504 Score = 52.0 bits (123), Expect = 1e-06 Identities = 45/199 (22%), Positives = 79/199 (39%) Frame = +3 Query: 6 VRLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPT 185 VR AVE + H +P++ + + R + V P Sbjct: 106 VRDKAVESLRKIADKHSSASLEEHFVPMLRRLATGDWFTSRTSACGLFSVVYPRVSPA-I 164 Query: 186 RADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRS 365 +++L + L RD+ VR AAA K+ +F ++ I+ + + +L D VR Sbjct: 165 KSELKSMFRTLCRDDTPMVRRAAAAKLGEFAKVFEKTAVIEGLHSSLTDLHVDEQDSVRL 224 Query: 366 ALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQS 545 + +L K + + PI + L D+ VR + KL ++ V+G D+ + Sbjct: 225 LTVESAIAFGTLLDKANKKKLIEPILIELFDDKSWRVRYMVAEKLIEIQNVLGEDMDTTH 284 Query: 546 LLPAIVELAEDRHWRVRLA 602 L+ L +D VR A Sbjct: 285 LVNMYTNLLKDPEGEVRCA 303 Score = 42.0 bits (97), Expect = 0.001 Identities = 45/179 (25%), Positives = 73/179 (40%), Gaps = 4/179 (2%) Frame = +3 Query: 105 QDKSWRVRYMVANQLYELCEAVGPEPTRADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRI 284 +D + VR A +L E + L + L D + VR+ F + Sbjct: 177 RDDTPMVRRAAAAKLGEFAKVFEKTAVIEGLHSSLTDLHVDEQDSVRLLTVESAIAFGTL 236 Query: 285 LSPQLAIQHILPCVKELSSDSSQHVRSALASVIMGMAPVLGKDATIEQLLPIFLSLLKDE 464 L + I P + EL D S VR +A ++ + VLG+D L+ ++ +LLKD Sbjct: 237 LDKANKKKLIEPILIELFDDKSWRVRYMVAEKLIEIQNVLGEDMDTTHLVNMYTNLLKDP 296 Query: 465 FPDVRLNIISKLDQVNQVIGID----LLSQSLLPAIVELAEDRHWRVRLAIIEYIPLLA 629 +VR +L + + D ++ SLL EL D + V+ + I LA Sbjct: 297 EGEVRCAATQRLQEFALNLPEDKRQNIICNSLLNVAKELVTDGNQLVKSELAGVIMGLA 355
>2AAA_YEAST (P31383) Protein phosphatase PP2A regulatory subunit A (PR65)| Length = 635 Score = 175 bits (443), Expect = 1e-43 Identities = 102/214 (47%), Positives = 136/214 (63%), Gaps = 5/214 (2%) Frame = +3 Query: 3 SVRLLAVEGCAALGKLLEPQDCVAH---ILPVIVNFSQDKSWRVRYMVANQLYELCEAVG 173 SV+ LAV+ ++ K + +H +L V D++WRVRYM A++ +L Sbjct: 253 SVKFLAVDCLISILKFFNAKGDESHTQDLLNSAVKLIGDEAWRVRYMAADRFSDLASQFS 312 Query: 174 PEPTRAD-LVPAYVRLLRDNEAEVRIAAAGKVTKFCRILS-PQLAIQHILPCVKELSSDS 347 D LV ++ L DNE +VR A A +V+ F + L+ P + + ILP V+ LS D Sbjct: 313 SNQAYIDELVQPFLNLCEDNEGDVREAVAKQVSGFAKFLNDPSIILNKILPAVQNLSMDE 372 Query: 348 SQHVRSALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGI 527 S+ VRSALAS I + +L KD I LPI L++L+DEFPDVRLNII+ L VN VIGI Sbjct: 373 SETVRSALASKITNIVLLLNKDQVINNFLPILLNMLRDEFPDVRLNIIASLKVVNDVIGI 432 Query: 528 DLLSQSLLPAIVELAEDRHWRVRLAIIEYIPLLA 629 +LLS SLLPAI ELA+D +WRVR+AIIEYIP+LA Sbjct: 433 ELLSDSLLPAITELAKDVNWRVRMAIIEYIPILA 466 Score = 64.7 bits (156), Expect = 2e-10 Identities = 41/173 (23%), Positives = 82/173 (47%) Frame = +3 Query: 48 LLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPTRADLVPAYVRLLRD 227 L +P + ILP + N S D+S VR +A+++ + + + + +P + +LRD Sbjct: 351 LNDPSIILNKILPAVQNLSMDESETVRSALASKITNIVLLLNKDQVINNFLPILLNMLRD 410 Query: 228 NEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRSALASVIMGMAPVLG 407 +VR+ + ++ +L +LP + EL+ D + VR A+ I +A LG Sbjct: 411 EFPDVRLNIIASLKVVNDVIGIELLSDSLLPAITELAKDVNWRVRMAIIEYIPILAEQLG 470 Query: 408 KDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVE 566 +QL + LS L D +R ++ L ++ ++ G D ++ +++ Sbjct: 471 MQFFDQQLSDLCLSWLWDTVYSIREAAVNNLKRLTEIFGSDWCRDEIISRLLK 523 Score = 56.6 bits (135), Expect = 6e-08 Identities = 41/175 (23%), Positives = 74/175 (42%), Gaps = 8/175 (4%) Frame = +3 Query: 78 ILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPTRADLVPAYVRLLRDNEAEVRIAAA 257 +LP I ++D +WRVR + + L E +G + L + L D +R AA Sbjct: 439 LLPAITELAKDVNWRVRMAIIEYIPILAEQLGMQFFDQQLSDLCLSWLWDTVYSIREAAV 498 Query: 258 GKVTKFCRILSPQLAIQHILPCVKELSSDSSQHV--RSALASVIMGMAPVLGKDATIEQL 431 + + I I+ + + ++ R + S + + PV+ D EQL Sbjct: 499 NNLKRLTEIFGSDWCRDEIISRLLKFDLQLLENFVSRFTILSALTTLVPVVSLDVVTEQL 558 Query: 432 LPIFLSLLKDEFPDVRLNIISKLDQVNQVIGID------LLSQSLLPAIVELAED 578 LP L D P++R N+ + +V+ D L+ ++LP++ L +D Sbjct: 559 LPFISHLADDGVPNIRFNVAKSYAVIVKVLIKDEAKYDALIKNTILPSLQTLFQD 613 Score = 52.0 bits (123), Expect = 1e-06 Identities = 39/167 (23%), Positives = 76/167 (45%) Frame = +3 Query: 126 RYMVANQLYELCEAVGPEPTRADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAI 305 R +L + A+GPE TR +L+P + +D+E EV A ++ KF + Sbjct: 54 RVEAMKKLDTIALALGPERTRNELIPFLTEVAQDDEDEVFAVLAEQLGKFVPYIGGPQYA 113 Query: 306 QHILPCVKELSSDSSQHVRSALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLN 485 +LP ++ L+S VR + +A L ++ +P+ L ++ +++ Sbjct: 114 TILLPVLEILASAEETLVREKAVDSLNNVAQELSQEQLFSDFVPLIEHLATADWFSSKVS 173 Query: 486 IISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVRLAIIEYIPLL 626 V I D L +++L ++LA+D V+ A+ + +P+L Sbjct: 174 ACGLFKSVIVRIKDDSLRKNILALYLQLAQDDTPMVKRAVGKNLPIL 220 Score = 43.5 bits (101), Expect = 5e-04 Identities = 42/193 (21%), Positives = 81/193 (41%) Frame = +3 Query: 9 RLLAVEGCAALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPTR 188 R+ A++ + L P+ ++P + +QD V ++A QL + +G Sbjct: 54 RVEAMKKLDTIALALGPERTRNELIPFLTEVAQDDEDEVFAVLAEQLGKFVPYIGGPQYA 113 Query: 189 ADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRSA 368 L+P L E VR A + + LS + +P ++ L++ + + Sbjct: 114 TILLPVLEILASAEETLVREKAVDSLNNVAQELSQEQLFSDFVPLIEHLATADWFSSKVS 173 Query: 369 LASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSL 548 + + + D+ + +L ++L L +D+ P V+ + K N I IDLL+Q+L Sbjct: 174 ACGLFKSVIVRIKDDSLRKNILALYLQLAQDDTPMVK-RAVGK----NLPILIDLLTQNL 228 Query: 549 LPAIVELAEDRHW 587 L+ D W Sbjct: 229 -----GLSTDEDW 236
>PP4R1_RAT (Q8VI02) Serine/threonine-protein phosphatase 4 regulatory subunit| 1 Length = 951 Score = 57.0 bits (136), Expect = 5e-08 Identities = 54/196 (27%), Positives = 90/196 (45%), Gaps = 10/196 (5%) Frame = +3 Query: 54 EPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYEL---CEAVGPEPTRAD---LVPAYVR 215 E +DC+A +L I + D VR + Q+ + C+ P A L+P VR Sbjct: 80 EERDCIA-VLERISRLADDSEPTVRAELMEQVPHIALFCQENRPSIPYAFSKYLLPIVVR 138 Query: 216 LLRDNEAEVR-IAAAGKVTKFCRILSPQLAIQ-HILPCVKELSS-DSSQHVRSALASVIM 386 L D +VR + A + + L +L ++ + P + +L++ DS+ V++ +++ Sbjct: 139 YLADQNNQVRKTSQAALLALLEQELIERLDVETKVCPVLIDLTAPDSNDDVKTEAVAIMC 198 Query: 387 GMAPVLGKDATIEQLLPIFLSLLKD-EFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIV 563 MAP++GKD T +LP F + D VR + + V+G + LLP Sbjct: 199 KMAPMVGKDITERLILPRFCEMCCDCRMFHVRKVCAANFGDICSVVGQQATEEMLLPRFF 258 Query: 564 ELAEDRHWRVRLAIIE 611 +L D W VR A E Sbjct: 259 QLCSDNVWGVRKACAE 274 Score = 50.8 bits (120), Expect = 3e-06 Identities = 36/128 (28%), Positives = 65/128 (50%), Gaps = 2/128 (1%) Frame = +3 Query: 102 SQDKSWRVRYMVANQLYELCEAVGPEPTRADLVPAYVRLLRDNEAEVRIAAAGKVTKFCR 281 + D W+VR +A ++EL +G + T ADLVP + L+D + EVRI + F + Sbjct: 673 ASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKDLD-EVRIGVLKHLHDFLK 731 Query: 282 ILSPQLAIQHILPCVKELSSDSSQH--VRSALASVIMGMAPVLGKDATIEQLLPIFLSLL 455 +L +++ + L +D+S++ R+ LA ++ + + + L PI L+L Sbjct: 732 LLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILLLELYSPRDVYDYLRPIALNLC 791 Query: 456 KDEFPDVR 479 D+ VR Sbjct: 792 ADKVSSVR 799 Score = 48.9 bits (115), Expect = 1e-05 Identities = 39/131 (29%), Positives = 62/131 (47%), Gaps = 9/131 (6%) Frame = +3 Query: 261 KVTKFCRILSPQLAI---QHILPCVKE----LSSDSSQHVRSALASVIMGMAPVLGKDAT 419 ++ K C P +A+ + C++E L+SD VR LA I +A +LG T Sbjct: 641 EIAKHCAYSLPGVALTLGRQNWHCLRETYETLASDMQWKVRRTLAFSIHELAVILGDQLT 700 Query: 420 IEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSL--LPAIVELAEDRHWRV 593 L+PIF LKD +VR+ ++ L +++ ID + L L + R+WR Sbjct: 701 AADLVPIFNGFLKD-LDEVRIGVLKHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRF 759 Query: 594 RLAIIEYIPLL 626 R + E + LL Sbjct: 760 RAELAEQLILL 770 Score = 35.0 bits (79), Expect = 0.18 Identities = 35/138 (25%), Positives = 53/138 (38%), Gaps = 6/138 (4%) Frame = +3 Query: 111 KSWRVRYMVANQLYELCEAVGPEPTRADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILS 290 ++WR R +A QL L E P L P + L D + VR + V++ + L Sbjct: 755 RNWRFRAELAEQLILLLELYSPRDVYDYLRPIALNLCADKVSSVRWISYKLVSEMVKKLH 814 Query: 291 ----PQLAIQHILPCVKELSSDSSQHVRSALASVIMGMAP--VLGKDATIEQLLPIFLSL 452 P ++ I V+ R A V + L D L+P L+L Sbjct: 815 MATPPTFGVELINELVENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTL 874 Query: 453 LKDEFPDVRLNIISKLDQ 506 D P+VR+ + L Q Sbjct: 875 ANDRVPNVRVLLAKTLRQ 892
>PP4R1_HUMAN (Q8TF05) Serine/threonine-protein phosphatase 4 regulatory subunit| 1 Length = 950 Score = 55.5 bits (132), Expect = 1e-07 Identities = 53/196 (27%), Positives = 89/196 (45%), Gaps = 10/196 (5%) Frame = +3 Query: 54 EPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYEL---CEAVGPEPTRAD---LVPAYVR 215 + +DC+A +L I + D VR + Q+ + C+ P A L+P VR Sbjct: 80 DERDCIA-VLERISRLADDSEPTVRAELMEQVPHIALFCQENRPSIPYAFSKFLLPIVVR 138 Query: 216 LLRDNEAEVR-IAAAGKVTKFCRILSPQLAIQ-HILPCVKELSS-DSSQHVRSALASVIM 386 L D +VR + A + + L + ++ + P + EL++ DS+ V++ +++ Sbjct: 139 YLADQNNQVRKTSQAALLALLEQELIERFDVETKVCPVLIELTAPDSNDDVKTEAVAIMC 198 Query: 387 GMAPVLGKDATIEQLLPIFLSLLKD-EFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIV 563 MAP++GKD T +LP F + D VR + + V+G + LLP Sbjct: 199 KMAPMVGKDITERLILPRFCEMCCDCRMFHVRKVCAANFGDICSVVGQQATEEMLLPRFF 258 Query: 564 ELAEDRHWRVRLAIIE 611 +L D W VR A E Sbjct: 259 QLCSDNVWGVRKACAE 274 Score = 51.6 bits (122), Expect = 2e-06 Identities = 41/157 (26%), Positives = 76/157 (48%), Gaps = 10/157 (6%) Frame = +3 Query: 102 SQDKSWRVRYMVANQLYELCEAVGPEPTRADLVPAYVRLLRDNEAEVRIAAAGKVTKFCR 281 + D W+VR +A ++EL +G + T ADLVP + L+D + EVRI + F + Sbjct: 672 ASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKDLD-EVRIGVLKHLHDFLK 730 Query: 282 ILSPQLAIQHILPCVKELSSDSSQH--VRSALASVIMGMAPVLGKDATIEQLLPIFLSLL 455 +L +++ + L +D+S++ R+ LA ++ + + + L PI L+L Sbjct: 731 LLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILLLELYSPRDVYDYLRPIALNLC 790 Query: 456 KDEFPDVR-------LNIISKLDQVN-QVIGIDLLSQ 542 D+ VR ++ KL G+DL+++ Sbjct: 791 ADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINE 827 Score = 48.9 bits (115), Expect = 1e-05 Identities = 39/131 (29%), Positives = 62/131 (47%), Gaps = 9/131 (6%) Frame = +3 Query: 261 KVTKFCRILSPQLAI---QHILPCVKE----LSSDSSQHVRSALASVIMGMAPVLGKDAT 419 ++ K C P +A+ + C++E L+SD VR LA I +A +LG T Sbjct: 640 EIAKHCAYSLPGVALTLGRQNWHCLRETYETLASDMQWKVRRTLAFSIHELAVILGDQLT 699 Query: 420 IEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSL--LPAIVELAEDRHWRV 593 L+PIF LKD +VR+ ++ L +++ ID + L L + R+WR Sbjct: 700 AADLVPIFNGFLKD-LDEVRIGVLKHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRF 758 Query: 594 RLAIIEYIPLL 626 R + E + LL Sbjct: 759 RAELAEQLILL 769 Score = 34.3 bits (77), Expect = 0.31 Identities = 35/138 (25%), Positives = 52/138 (37%), Gaps = 6/138 (4%) Frame = +3 Query: 111 KSWRVRYMVANQLYELCEAVGPEPTRADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILS 290 ++WR R +A QL L E P L P + L D + VR + V++ + L Sbjct: 754 RNWRFRAELAEQLILLLELYSPRDVYDYLRPIALNLCADKVSSVRWISYKLVSEMVKKLH 813 Query: 291 ----PQLAIQHILPCVKELSSDSSQHVRSALASVIMGMAP--VLGKDATIEQLLPIFLSL 452 P + I V+ R A V + L D L+P L+L Sbjct: 814 AATPPTFGVDLINELVENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTL 873 Query: 453 LKDEFPDVRLNIISKLDQ 506 D P+VR+ + L Q Sbjct: 874 ANDRVPNVRVLLAKTLRQ 891
>PP4R1_MOUSE (Q8K2V1) Serine/threonine-protein phosphatase 4 regulatory subunit| 1 Length = 951 Score = 54.3 bits (129), Expect = 3e-07 Identities = 52/196 (26%), Positives = 89/196 (45%), Gaps = 10/196 (5%) Frame = +3 Query: 54 EPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYEL---CEAVGPEPTRAD---LVPAYVR 215 + +DC+A +L I + D VR + Q+ + C+ P A L+P VR Sbjct: 80 DERDCIA-VLERISRLADDSEPTVRAELMEQVPHIALFCQENRPSIPYAFSKYLLPIVVR 138 Query: 216 LLRDNEAEVR-IAAAGKVTKFCRILSPQLAIQ-HILPCVKELSS-DSSQHVRSALASVIM 386 L D +VR + A + + L + ++ + P + +L++ DS+ V++ +++ Sbjct: 139 YLADQNNQVRKTSQAALLALLEQELIERFDVETKVCPVLIDLTAPDSNDDVKTEAVAIMC 198 Query: 387 GMAPVLGKDATIEQLLPIFLSLLKD-EFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIV 563 MAP++GKD T +LP F + D VR + + V+G + LLP Sbjct: 199 KMAPMVGKDITERLILPRFCEMCCDCRMFHVRKVCAANFGDICSVVGQQATEEMLLPRFF 258 Query: 564 ELAEDRHWRVRLAIIE 611 +L D W VR A E Sbjct: 259 QLCSDNVWGVRKACAE 274 Score = 51.6 bits (122), Expect = 2e-06 Identities = 41/157 (26%), Positives = 76/157 (48%), Gaps = 10/157 (6%) Frame = +3 Query: 102 SQDKSWRVRYMVANQLYELCEAVGPEPTRADLVPAYVRLLRDNEAEVRIAAAGKVTKFCR 281 + D W+VR +A ++EL +G + T ADLVP + L+D + EVRI + F + Sbjct: 673 ASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKDLD-EVRIGVLKHLHDFLK 731 Query: 282 ILSPQLAIQHILPCVKELSSDSSQH--VRSALASVIMGMAPVLGKDATIEQLLPIFLSLL 455 +L +++ + L +D+S++ R+ LA ++ + + + L PI L+L Sbjct: 732 LLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILLLELYSPRDVYDYLRPIALNLC 791 Query: 456 KDEFPDVR-------LNIISKLDQVN-QVIGIDLLSQ 542 D+ VR ++ KL G+DL+++ Sbjct: 792 ADKVSSVRWISYKLVSEMVKKLHTATPPTFGVDLINE 828 Score = 48.9 bits (115), Expect = 1e-05 Identities = 39/131 (29%), Positives = 62/131 (47%), Gaps = 9/131 (6%) Frame = +3 Query: 261 KVTKFCRILSPQLAI---QHILPCVKE----LSSDSSQHVRSALASVIMGMAPVLGKDAT 419 ++ K C P +A+ + C++E L+SD VR LA I +A +LG T Sbjct: 641 EIAKHCAYSLPGVALTLGRQNWHCLRETYETLASDMQWKVRRTLAFSIHELAVILGDQLT 700 Query: 420 IEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSL--LPAIVELAEDRHWRV 593 L+PIF LKD +VR+ ++ L +++ ID + L L + R+WR Sbjct: 701 AADLVPIFNGFLKD-LDEVRIGVLKHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRF 759 Query: 594 RLAIIEYIPLL 626 R + E + LL Sbjct: 760 RAELAEQLILL 770 Score = 34.3 bits (77), Expect = 0.31 Identities = 35/138 (25%), Positives = 52/138 (37%), Gaps = 6/138 (4%) Frame = +3 Query: 111 KSWRVRYMVANQLYELCEAVGPEPTRADLVPAYVRLLRDNEAEVRIAAAGKVTKFCRILS 290 ++WR R +A QL L E P L P + L D + VR + V++ + L Sbjct: 755 RNWRFRAELAEQLILLLELYSPRDVYDYLRPIALNLCADKVSSVRWISYKLVSEMVKKLH 814 Query: 291 ----PQLAIQHILPCVKELSSDSSQHVRSALASVIMGMAP--VLGKDATIEQLLPIFLSL 452 P + I V+ R A V + L D L+P L+L Sbjct: 815 TATPPTFGVDLINELVENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTL 874 Query: 453 LKDEFPDVRLNIISKLDQ 506 D P+VR+ + L Q Sbjct: 875 ANDRVPNVRVLLAKTLRQ 892
>PP4RL_HUMAN (Q9P1A2) Serine/threonine-protein phosphatase 4 regulatory subunit| 1-like Length = 438 Score = 47.8 bits (112), Expect = 3e-05 Identities = 34/128 (26%), Positives = 64/128 (50%), Gaps = 2/128 (1%) Frame = +3 Query: 102 SQDKSWRVRYMVANQLYELCEAVGPEPTRADLVPAYVRLLRDNEAEVRIAAAGKVTKFCR 281 + D W+VR +A ++EL +G + T ADLVP + L+D + EVRI + F + Sbjct: 162 ASDVQWKVRRALAFSIHELAVILGDQLTAADLVPIFNGFLKDLD-EVRIGVLRHLYDFLK 220 Query: 282 ILSPQLAIQHILPCVKELSSDSSQH--VRSALASVIMGMAPVLGKDATIEQLLPIFLSLL 455 +L ++ + + +D+S++ R LA ++ + + + + L+ I L L Sbjct: 221 LLHEDKRRDYLYQLQEFVVTDNSRNWRFRYELAEQLILILELYSPNDVYDYLMHIALKLC 280 Query: 456 KDEFPDVR 479 D+ +VR Sbjct: 281 ADQVSEVR 288 Score = 45.4 bits (106), Expect = 1e-04 Identities = 39/130 (30%), Positives = 60/130 (46%), Gaps = 9/130 (6%) Frame = +3 Query: 264 VTKFCRILSPQLAI---QHILPCVKE----LSSDSSQHVRSALASVIMGMAPVLGKDATI 422 + K C P +A+ + C+K+ L+SD VR ALA I +A +LG T Sbjct: 131 IAKHCAYSLPGVALTLGRQNWHCLKDTYETLASDVQWKVRRALAFSIHELAVILGDQLTA 190 Query: 423 EQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSL--LPAIVELAEDRHWRVR 596 L+PIF LKD +VR+ ++ L +++ D L L V R+WR R Sbjct: 191 ADLVPIFNGFLKD-LDEVRIGVLRHLYDFLKLLHEDKRRDYLYQLQEFVVTDNSRNWRFR 249 Query: 597 LAIIEYIPLL 626 + E + L+ Sbjct: 250 YELAEQLILI 259 Score = 42.0 bits (97), Expect = 0.001 Identities = 38/139 (27%), Positives = 57/139 (41%), Gaps = 6/139 (4%) Frame = +3 Query: 111 KSWRVRYMVANQLYELCEAVGPEPTRADLVPAYVRLLRDNEAEVRIAAAGKVT----KFC 278 ++WR RY +A QL + E P L+ ++L D +EVR + V KF Sbjct: 244 RNWRFRYELAEQLILILELYSPNDVYDYLMHIALKLCADQVSEVRWISFKLVVAILQKFY 303 Query: 279 RILSPQLAIQHILPCVKELSSDSSQHVRSALASVIMGMAP--VLGKDATIEQLLPIFLSL 452 L + I + S R A A + + + D +E LLP LSL Sbjct: 304 SNSESALGLNFINELIIRFRHCSKWVGRQAFAFICQAVVSKECVPVDQFMEHLLPSLLSL 363 Query: 453 LKDEFPDVRLNIISKLDQV 509 D P+VR+ + L Q+ Sbjct: 364 ASDPVPNVRVLLAKALRQM 382
>PI3R4_PONPY (Q5R9I3) Phosphoinositide 3-kinase regulatory subunit 4 (EC| 2.7.11.1) (PI3-kinase regulatory subunit 4) Length = 1357 Score = 46.6 bits (109), Expect = 6e-05 Identities = 34/117 (29%), Positives = 56/117 (47%), Gaps = 6/117 (5%) Frame = +3 Query: 297 LAIQHILPCVKELSSDSSQHVRSALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDV 476 + + I C++ L S + A +I+ +AP LG + ++++ P L D P V Sbjct: 376 ILVSVITSCLQTLKYYDS---KLAALELILHLAPRLGVEILLDRITPYLLHFSNDSVPRV 432 Query: 477 RLNIISKLDQVNQVI------GIDLLSQSLLPAIVELAEDRHWRVRLAIIEYIPLLA 629 R + L +V ++ I++ + +LP I LA+D VRLA E I LLA Sbjct: 433 RAEALRTLTKVLALVKEVPRNDINIYPEYILPGIAHLAQDDATIVRLAYAENIALLA 489
>PI3R4_MOUSE (Q8VD65) Phosphoinositide 3-kinase regulatory subunit 4 (EC| 2.7.11.1) (PI3-kinase regulatory subunit 4) Length = 1357 Score = 45.8 bits (107), Expect = 1e-04 Identities = 33/112 (29%), Positives = 54/112 (48%), Gaps = 6/112 (5%) Frame = +3 Query: 312 ILPCVKELSSDSSQHVRSALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNII 491 I C++ L S S + A +I+ +AP L + ++++ P L D P VR + Sbjct: 381 ITSCLQTLKSCDS---KLAALELILHLAPRLSVEILLDRITPYLLHFSNDSVPRVRAEAL 437 Query: 492 SKLDQVNQVI------GIDLLSQSLLPAIVELAEDRHWRVRLAIIEYIPLLA 629 L +V ++ +++ + +LP I LA+D VRLA E I LLA Sbjct: 438 RTLTKVLALVQEVPRNDVNIYPEYILPGIAHLAQDDATIVRLAYAENIALLA 489
>PI3R4_HUMAN (Q99570) Phosphoinositide 3-kinase regulatory subunit 4 (EC| 2.7.11.1) (PI3-kinase regulatory subunit 4) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Length = 1357 Score = 44.3 bits (103), Expect = 3e-04 Identities = 33/117 (28%), Positives = 55/117 (47%), Gaps = 6/117 (5%) Frame = +3 Query: 297 LAIQHILPCVKELSSDSSQHVRSALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDV 476 + + I C++ L S + A +I+ +AP L + ++++ P L D P V Sbjct: 376 ILVSVITSCLQTLKYCDS---KLAALELILHLAPRLSVEILLDRITPYLLHFSNDSVPRV 432 Query: 477 RLNIISKLDQVNQVI------GIDLLSQSLLPAIVELAEDRHWRVRLAIIEYIPLLA 629 R + L +V ++ I++ + +LP I LA+D VRLA E I LLA Sbjct: 433 RAEALRTLTKVLALVKEVPRNDINIYPEYILPGIAHLAQDDATIVRLAYAENIALLA 489
>PI3R4_RAT (P0C0R5) Phosphoinositide 3-kinase regulatory subunit 4 (EC| 2.7.11.1) (PI3-kinase regulatory subunit 4) Length = 1357 Score = 43.9 bits (102), Expect = 4e-04 Identities = 32/112 (28%), Positives = 54/112 (48%), Gaps = 6/112 (5%) Frame = +3 Query: 312 ILPCVKELSSDSSQHVRSALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNII 491 I C++ L S S + A +I+ +AP L + ++++ P L + P VR + Sbjct: 381 ITSCLQTLKSCDS---KLAALELILHLAPRLSVEILLDRITPYLLHFSNNSVPRVRAEAL 437 Query: 492 SKLDQVNQVI------GIDLLSQSLLPAIVELAEDRHWRVRLAIIEYIPLLA 629 L +V ++ +++ + +LP I LA+D VRLA E I LLA Sbjct: 438 RTLTKVLALVQEVPRNDVNIYPEYILPGIAHLAQDDATIVRLAYAENIALLA 489
>IMB1_HUMAN (Q14974) Importin beta-1 subunit (Karyopherin beta-1 subunit)| (Nuclear factor P97) (Importin 90) Length = 876 Score = 41.6 bits (96), Expect = 0.002 Identities = 28/89 (31%), Positives = 42/89 (47%), Gaps = 5/89 (5%) Frame = +3 Query: 63 DCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPTR-----ADLVPAYVRLLRD 227 D V H+LP I ++ W RY A + C GPEP++ +P + L++D Sbjct: 362 DIVPHVLPFIKEHIKNPDW--RYRDAAVMAFGCILEGPEPSQLKPLVIQAMPTLIELMKD 419 Query: 228 NEAEVRIAAAGKVTKFCRILSPQLAIQHI 314 VR AA V + C +L P+ AI + Sbjct: 420 PSVVVRDTAAWTVGRICELL-PEAAINDV 447
>IMB1_RAT (P52296) Importin beta-1 subunit (Karyopherin beta-1 subunit)| (Nuclear factor P97) Length = 875 Score = 40.0 bits (92), Expect = 0.006 Identities = 26/89 (29%), Positives = 39/89 (43%), Gaps = 5/89 (5%) Frame = +3 Query: 63 DCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPTR-----ADLVPAYVRLLRD 227 D V H+LP I ++ WR R + E GPEP + +P + L++D Sbjct: 361 DIVPHVLPFIKEHIKNPDWRYRDAAVMAFGSILE--GPEPNQLKPLVIQAMPTLIELMKD 418 Query: 228 NEAEVRIAAAGKVTKFCRILSPQLAIQHI 314 VR A V + C +L P+ AI + Sbjct: 419 PSVVVRDTTAWTVGRICELL-PEAAINDV 446
>IMB1_MOUSE (P70168) Importin beta-1 subunit (Karyopherin beta-1 subunit)| (Nuclear factor P97) (Pore targeting complex 97 kDa subunit) (PTAC97) (SCG) Length = 876 Score = 39.7 bits (91), Expect = 0.007 Identities = 26/89 (29%), Positives = 39/89 (43%), Gaps = 5/89 (5%) Frame = +3 Query: 63 DCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPTR-----ADLVPAYVRLLRD 227 D V H+LP I ++ WR R + E GPEP + +P + L++D Sbjct: 362 DIVPHVLPFIKEHIKNPDWRYRDAAVVAFGSILE--GPEPNQLKPLVIQAMPTLIELMKD 419 Query: 228 NEAEVRIAAAGKVTKFCRILSPQLAIQHI 314 VR A V + C +L P+ AI + Sbjct: 420 PSVVVRDTTAWTVGRICELL-PEAAINDV 447
>GCN1_YEAST (P33892) Translational activator GCN1| Length = 2672 Score = 39.3 bits (90), Expect = 0.010 Identities = 40/189 (21%), Positives = 89/189 (47%), Gaps = 5/189 (2%) Frame = +3 Query: 69 VAHILPVIVNFSQDKSWRVR----YMVANQLYELCEAVGPEPTRADLVPAYVRLLRDNEA 236 V ++PV V+ + +WR + ++ N Y + + + +VP V +L D+ Sbjct: 1445 VKKLIPVAVSNLDEIAWRTKRGSVQLLGNMAY--LDPTQLSASLSTIVPEIVGVLNDSHK 1502 Query: 237 EVRIAAAGKVTKFCRIL-SPQLAIQHILPCVKELSSDSSQHVRSALASVIMGMAPVLGKD 413 EVR AA + +F ++ +P+ IQ ++P + + D +++ AL S+I Sbjct: 1503 EVRKAADESLKRFGEVIRNPE--IQKLVPVLLQAIGDPTKYTEEALDSLIQTQFVHYIDG 1560 Query: 414 ATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRV 593 + L + + ++ D NI K ++ + I + ++ L+P + +L ++ V Sbjct: 1561 PS----LALIIHIIHRGMHDRSANIKRKACKIVGNMAILVDTKDLIPYLQQLIDE----V 1612 Query: 594 RLAIIEYIP 620 +A+++ +P Sbjct: 1613 EIAMVDPVP 1621
>SF3B1_SCHPO (Q10178) U2 snRNP component prp10| Length = 1188 Score = 38.9 bits (89), Expect = 0.013 Identities = 24/103 (23%), Positives = 54/103 (52%), Gaps = 6/103 (5%) Frame = +3 Query: 339 SDSSQHVRSALASVIMGMAPVL---GKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQV 509 ++ S +VR A ++ + VL G++A + +L + L +E+P+V +I+ + + Sbjct: 825 NNKSANVREQAADLVSSITIVLKACGEEALMRKLGVVLYEYLGEEYPEVLGSILGAIKAI 884 Query: 510 NQVIGIDLLS---QSLLPAIVELAEDRHWRVRLAIIEYIPLLA 629 V+G+ + + LLP + + +RH +V+ I+ + +A Sbjct: 885 VSVVGMSSMQPPIRDLLPRLTPILRNRHEKVQENTIDLVGKIA 927
>VPS15_PICPA (Q9UVG6) Putative serine/threonine-protein kinase VPS15 (EC| 2.7.11.1) (Vacuolar protein sorting protein 15) Length = 1339 Score = 37.4 bits (85), Expect = 0.037 Identities = 22/83 (26%), Positives = 41/83 (49%) Frame = +3 Query: 330 ELSSDSSQHVRSALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQV 509 +L D + +L I+ +A V GKD T + +L ++ L D ++R+ I + + Sbjct: 536 QLLIDPDSSAKISLLKNILPLASVFGKDKTNDIILSHMITYLNDPDENLRVAFIESILGL 595 Query: 510 NQVIGIDLLSQSLLPAIVELAED 578 + +GI L +LP +V+ D Sbjct: 596 SIFVGITSLENYILPLLVQTLTD 618 Score = 37.4 bits (85), Expect = 0.037 Identities = 37/184 (20%), Positives = 79/184 (42%), Gaps = 15/184 (8%) Frame = +3 Query: 12 LLAVEGCAALGKLLEPQDCVAHILPVIVNF-SQDKSWRVRYMVANQL----------YEL 158 LL V+ + L+ P+ +ILP + +F S K +R + A L YE+ Sbjct: 458 LLLVDYLTPVNVLIFPE----YILPKLASFLSTTKGSYMRMIFATILPHLAKTALKFYEM 513 Query: 159 CEAVGPEPTRADLVPAY----VRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCV 326 +G + +L+ + ++LL D ++ +I+ + + IL + Sbjct: 514 AILLGSHVEKFELLKNFENLTIQLLIDPDSSAKISLLKNILPLASVFGKDKTNDIILSHM 573 Query: 327 KELSSDSSQHVRSALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQ 506 +D +++R A I+G++ +G + +LP+ + L D V +N++ + Sbjct: 574 ITYLNDPDENLRVAFIESILGLSIFVGITSLENYILPLLVQTLTDNSEIVVVNVLRSFAE 633 Query: 507 VNQV 518 +N + Sbjct: 634 LNNL 637
>YAQ5_SCHPO (Q10105) Putative translational activator C18G6.05c (GCN1 homolog)| Length = 2670 Score = 36.2 bits (82), Expect = 0.082 Identities = 47/205 (22%), Positives = 87/205 (42%), Gaps = 12/205 (5%) Frame = +3 Query: 39 LGKLLEPQDCVAHI---LPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPTRADLVPAY 209 + L EP++ ++ +P + D R A L L E +G E L+P Sbjct: 1626 MASLTEPENLAVYLESLMPRLREVLIDPVPDTRATAAKALGSLIEKLG-EKKFPTLIPEL 1684 Query: 210 VRLLRDNEAEV-RIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRSALASVIM 386 +LR +EV R AA +++ L ++ +LP + + +S H+R + S+++ Sbjct: 1685 FNVLRSECSEVDRQGAAQGLSEILAGLG-LARLEDVLPEILKNTSSPVPHIRESFISLLI 1743 Query: 387 GMAPVLGK--DATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIG------IDLLSQ 542 + G + + +P LS L D D L + L ++ +DLL Sbjct: 1744 YLPATFGSRFQPYLARAIPPILSGLAD---DSELVQTASLRAAKMIVNNYATKSVDLL-- 1798 Query: 543 SLLPAIVELAEDRHWRVRLAIIEYI 617 LP + + D WR+RL+ ++ + Sbjct: 1799 --LPELEKGLFDNAWRIRLSSVQLV 1821 Score = 31.6 bits (70), Expect = 2.0 Identities = 35/168 (20%), Positives = 72/168 (42%), Gaps = 2/168 (1%) Frame = +3 Query: 81 LPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPTRADLVPAYVRLLRDNEAEVRIAAAG 260 L +++ Q+ + R + A + + + EP DL+P + DN EVR A Sbjct: 1406 LSELISNRQNATHRQVALFAVEAFSRILGIYFEPYLPDLLPLLLTSFGDNANEVREATMD 1465 Query: 261 KVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRSALASVIMGMAPVLGKDATI--EQLL 434 V + LS ++ +LP + + ++ + + A ++ M+ + K ++ ++ Sbjct: 1466 AVKQIMSQLS-AFGVKLLLPTLLDGLNEYNWRSKKASVEILGLMSYMAPKQLSVFLPTII 1524 Query: 435 PIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAED 578 P +L D VR L + VI + Q+L+P +++ D Sbjct: 1525 PKLSEVLTDSHSQVRNTANKSLLRFGDVISNPEI-QTLVPTLLKALSD 1571 Score = 29.6 bits (65), Expect = 7.7 Identities = 29/114 (25%), Positives = 58/114 (50%), Gaps = 7/114 (6%) Frame = +3 Query: 309 HILPCVKELSSD--SSQHVRSALASVIMGMAPVLGK--DATIEQLLPIFLSLLKDEFPDV 476 +IL + EL S+ ++ H + AL +V + +LG + + LLP+ L+ D +V Sbjct: 1401 NILDSLSELISNRQNATHRQVALFAV-EAFSRILGIYFEPYLPDLLPLLLTSFGDNANEV 1459 Query: 477 RLNIISKLDQVNQVI---GIDLLSQSLLPAIVELAEDRHWRVRLAIIEYIPLLA 629 R + + Q+ + G+ LL LP +++ + +WR + A +E + L++ Sbjct: 1460 REATMDAVKQIMSQLSAFGVKLL----LPTLLDGLNEYNWRSKKASVEILGLMS 1509
>TOR2_SCHPO (Q9Y7K2) Phosphatidylinositol 3-kinase tor2 (EC 2.7.1.137)| (PtdIns-3-kinase tor2) (PI3-kinase tor2) (PI3K tor2) Length = 2337 Score = 36.2 bits (82), Expect = 0.082 Identities = 26/79 (32%), Positives = 41/79 (51%), Gaps = 2/79 (2%) Frame = +3 Query: 33 AALGKLLEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPE--PTRADLVPA 206 AA +L+E V IL +++ ++D S V + N L E+C+ G P DL+P Sbjct: 634 AAAPRLIESH--VEPILQILLPKAKDSSSIVAASIVNSLGEICQISGEVIVPFIKDLMPL 691 Query: 207 YVRLLRDNEAEVRIAAAGK 263 + L+D + +R AAA K Sbjct: 692 IIEALQDQSSPIRRAAALK 710
>IMB_DROME (O18388) Importin beta subunit (Karyopherin beta-4 subunit)| (Protein ketel) Length = 884 Score = 35.0 bits (79), Expect = 0.18 Identities = 30/103 (29%), Positives = 45/103 (43%), Gaps = 9/103 (8%) Frame = +3 Query: 63 DCVAHILPVIVNFSQDKSWRVR---YMVANQLYELCEAVGPEPTRADLVPAYVRLLRDNE 233 + V H+LP I + +WR R M + E +P +P +RL+ D+ Sbjct: 368 EIVPHVLPFIKENIESPNWRFRDAAVMTFGSVLNGLETNTLKPLVEQAMPTLIRLMYDSS 427 Query: 234 AEVRIAAAGKVTKFCRILSPQLAI-----QHILPC-VKELSSD 344 VR A + C I+ P+ AI Q +L C VK L S+ Sbjct: 428 VIVRDTIAWTFGRICDII-PEAAINETYLQTLLECFVKSLKSE 469
>SF3B1_MOUSE (Q99NB9) Splicing factor 3B subunit 1 (Spliceosome-associated protein| 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit) Length = 1304 Score = 33.9 bits (76), Expect = 0.41 Identities = 27/104 (25%), Positives = 53/104 (50%), Gaps = 7/104 (6%) Frame = +3 Query: 339 SDSSQHVRSALASVIMGMAPVLGKDATIEQLLP----IFLSLLKDEFPDVRLNIISKLDQ 506 ++ S VR A +I A V+ K E+L+ + L +E+P+V +I+ L Sbjct: 941 NNKSAKVRQQAADLISRTAVVM-KTCQEEKLMGHLGVVLYEYLGEEYPEVLGSILGALKA 999 Query: 507 VNQVIGIDLLS---QSLLPAIVELAEDRHWRVRLAIIEYIPLLA 629 + VIG+ ++ + LLP + + ++RH +V+ I+ + +A Sbjct: 1000 IVNVIGMHKMTPPIKDLLPRLTPILKNRHEKVQENCIDLVGRIA 1043
>SF3B1_HUMAN (O75533) Splicing factor 3B subunit 1 (Spliceosome-associated protein| 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit) Length = 1304 Score = 33.9 bits (76), Expect = 0.41 Identities = 27/104 (25%), Positives = 53/104 (50%), Gaps = 7/104 (6%) Frame = +3 Query: 339 SDSSQHVRSALASVIMGMAPVLGKDATIEQLLP----IFLSLLKDEFPDVRLNIISKLDQ 506 ++ S VR A +I A V+ K E+L+ + L +E+P+V +I+ L Sbjct: 941 NNKSAKVRQQAADLISRTAVVM-KTCQEEKLMGHLGVVLYEYLGEEYPEVLGSILGALKA 999 Query: 507 VNQVIGIDLLS---QSLLPAIVELAEDRHWRVRLAIIEYIPLLA 629 + VIG+ ++ + LLP + + ++RH +V+ I+ + +A Sbjct: 1000 IVNVIGMHKMTPPIKDLLPRLTPILKNRHEKVQENCIDLVGRIA 1043
>SF3B1_XENLA (O57683) Splicing factor 3B subunit 1 (Spliceosome-associated protein| 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit) (146 kDa nuclear protein) Length = 1307 Score = 33.9 bits (76), Expect = 0.41 Identities = 27/104 (25%), Positives = 53/104 (50%), Gaps = 7/104 (6%) Frame = +3 Query: 339 SDSSQHVRSALASVIMGMAPVLGKDATIEQLLP----IFLSLLKDEFPDVRLNIISKLDQ 506 ++ S VR A +I A V+ K E+L+ + L +E+P+V +I+ L Sbjct: 944 NNKSAKVRQQAADLISRTAVVM-KTCQEEKLMGHLGVVLYEYLGEEYPEVLGSILGALKA 1002 Query: 507 VNQVIGIDLLS---QSLLPAIVELAEDRHWRVRLAIIEYIPLLA 629 + VIG+ ++ + LLP + + ++RH +V+ I+ + +A Sbjct: 1003 IVNVIGMHKMTPPIKDLLPRLTPILKNRHEKVQENCIDLVGRIA 1046
>YIBA_ECOLI (P0ADK6) Protein yibA| Length = 280 Score = 33.5 bits (75), Expect = 0.53 Identities = 39/133 (29%), Positives = 58/133 (43%), Gaps = 3/133 (2%) Frame = +3 Query: 219 LRDNEAEVRIAAAGKVTKFCR---ILSPQLAIQHILPCVKELSSDSSQHVRSALASVIMG 389 L D A VR A + C+ I SP++ Q + D S +VR A A I Sbjct: 100 LNDKSACVRATAIESTAQRCKKNPIYSPKIVEQSQITAF-----DKSTNVRRATAFAIS- 153 Query: 390 MAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVEL 569 V+ ATI P+ ++LLKD DVR N + +N+ D+ VE+ Sbjct: 154 ---VINDKATI----PLLINLLKDPNGDVR-NWAAFAININKYDNSDIRD-----CFVEM 200 Query: 570 AEDRHWRVRLAII 608 +D++ VR+ I Sbjct: 201 LQDKNEEVRIEAI 213
>YIBA_ECO57 (P0ADK7) Protein yibA| Length = 280 Score = 33.5 bits (75), Expect = 0.53 Identities = 39/133 (29%), Positives = 58/133 (43%), Gaps = 3/133 (2%) Frame = +3 Query: 219 LRDNEAEVRIAAAGKVTKFCR---ILSPQLAIQHILPCVKELSSDSSQHVRSALASVIMG 389 L D A VR A + C+ I SP++ Q + D S +VR A A I Sbjct: 100 LNDKSACVRATAIESTAQRCKKNPIYSPKIVEQSQITAF-----DKSTNVRRATAFAIS- 153 Query: 390 MAPVLGKDATIEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVEL 569 V+ ATI P+ ++LLKD DVR N + +N+ D+ VE+ Sbjct: 154 ---VINDKATI----PLLINLLKDPNGDVR-NWAAFAININKYDNSDIRD-----CFVEM 200 Query: 570 AEDRHWRVRLAII 608 +D++ VR+ I Sbjct: 201 LQDKNEEVRIEAI 213
>IMB4_SCHPO (O60100) Probable importin beta-4 subunit (Karyopherin beta-4| subunit) (Importin 123) Length = 1067 Score = 32.7 bits (73), Expect = 0.91 Identities = 33/130 (25%), Positives = 62/130 (47%), Gaps = 6/130 (4%) Frame = +3 Query: 84 PVIVNFSQDKSWRVRYMVANQLYELCEAVGPE--PTRADLVPAYVRLLRDNEAEVRIAAA 257 P IV + K+ R M + E+ + P D+ ++ L D+E EVR AA Sbjct: 856 PQIVKYYMSKNGNERAMAVACVGEVAGGIESAITPFTRDVFSLFMAALEDSEGEVRSNAA 915 Query: 258 GKVTKFCRILSPQLAIQHILPCVKELSSDSSQHV-RSALASVIMGMAPVLGKDAT---IE 425 + C+ + L+ ++ L +++L +Q V R+AL + I ++ ++ + ++ Sbjct: 916 YSMGLLCQFSTEDLSSEY-LNILQKLQPFFTQEVFRTALDNAIGCISRLILHNQNAIPVD 974 Query: 426 QLLPIFLSLL 455 Q+LPI S L Sbjct: 975 QVLPIVFSKL 984
>HRJ97_HUMAN (Q86Y56) Heat repeats-containing protein FLJ20397| Length = 855 Score = 32.7 bits (73), Expect = 0.91 Identities = 31/99 (31%), Positives = 47/99 (47%), Gaps = 4/99 (4%) Frame = +3 Query: 195 LVPAYVRLLRDNEAEVRIAA---AGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRS 365 L+ ++ + +VR+AA G V F S + H + L D Q VR Sbjct: 208 LIGPLMQTISHQHWKVRVAAIEATGAVIHFGNGKSVDDVLSHF---AQRLFDDVPQ-VRR 263 Query: 366 ALASVIMGMAPVL-GKDATIEQLLPIFLSLLKDEFPDVR 479 A+ASV+ G L + + +L+P+ LS L DE P+VR Sbjct: 264 AVASVVGGWLLCLRDRYSFFHKLIPLLLSSLNDEVPEVR 302
>K0562_HUMAN (O60308) Protein KIAA0562| Length = 925 Score = 31.2 bits (69), Expect = 2.6 Identities = 17/54 (31%), Positives = 29/54 (53%) Frame = +3 Query: 51 LEPQDCVAHILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPTRADLVPAYV 212 LE CV +PV++ + D S R+R AN + E+ A+ E ++P+Y+ Sbjct: 520 LETAHCVERTIPVLLTRTGDSSARLRVTAANFIQEM--ALFKEVKSLQIIPSYL 571
>E13B_NICPL (P23431) Glucan endo-1,3-beta-glucosidase, basic vacuolar isoform| precursor (EC 3.2.1.39) ((1->3)-beta-glucan endohydrolase) ((1->3)-beta-glucanase) (Beta-1,3-endoglucanase, basic) Length = 365 Score = 30.0 bits (66), Expect = 5.9 Identities = 13/39 (33%), Positives = 25/39 (64%) Frame = +3 Query: 453 LKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVEL 569 +KD +PDV++ I+ ++++ V G L+ L PA+V + Sbjct: 111 VKDFWPDVKIKYIAVGNEISPVTGTSYLTSFLTPAMVNI 149
>E13F_TOBAC (P27666) Glucan endo-1,3-beta-glucosidase, basic vacuolar isoform| GLB precursor (EC 3.2.1.39) ((1->3)-beta-glucan endohydrolase) ((1->3)-beta-glucanase) (Beta-1,3-endoglucanase, basic) (Glucanase GLB) Length = 370 Score = 30.0 bits (66), Expect = 5.9 Identities = 13/39 (33%), Positives = 25/39 (64%) Frame = +3 Query: 453 LKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVEL 569 +KD +PDV++ I+ ++++ V G L+ L PA+V + Sbjct: 111 VKDFWPDVKIKYIAVGNEISPVTGTSYLTSFLTPAMVNI 149
>E13E_TOBAC (P23546) Glucan endo-1,3-beta-glucosidase, basic vacuolar isoform| GGIB50 precursor (EC 3.2.1.39) ((1->3)-beta-glucan endohydrolase) ((1->3)-beta-glucanase) (Beta-1,3-endoglucanase, basic) (Glucanase GLA) Length = 370 Score = 30.0 bits (66), Expect = 5.9 Identities = 13/39 (33%), Positives = 25/39 (64%) Frame = +3 Query: 453 LKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVEL 569 +KD +PDV++ I+ ++++ V G L+ L PA+V + Sbjct: 111 VKDFWPDVKIKYIAVGNEISPVTGTSYLTSFLTPAMVNI 149
>DYH5_HUMAN (Q8TE73) Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy| chain 5) (HL1) Length = 4624 Score = 30.0 bits (66), Expect = 5.9 Identities = 14/61 (22%), Positives = 35/61 (57%) Frame = +3 Query: 303 IQHILPCVKELSSDSSQHVRSALASVIMGMAPVLGKDATIEQLLPIFLSLLKDEFPDVRL 482 +++IL ++ L + + ++++M + + I++ P+FLSL++D FP++ L Sbjct: 2155 LRNILSVLRTLGAAKRANPMDTESTIVMRVLRDMNLSKLIDEDEPLFLSLIEDLFPNILL 2214 Query: 483 N 485 + Sbjct: 2215 D 2215
>E13B_TOBAC (P15797) Glucan endo-1,3-beta-glucosidase, basic vacuolar isoform| precursor (EC 3.2.1.39) ((1->3)-beta-glucan endohydrolase) ((1->3)-beta-glucanase) (Beta-1,3-endoglucanase, basic) Length = 371 Score = 30.0 bits (66), Expect = 5.9 Identities = 13/39 (33%), Positives = 25/39 (64%) Frame = +3 Query: 453 LKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVEL 569 +KD +PDV++ I+ ++++ V G L+ L PA+V + Sbjct: 112 VKDFWPDVKIKYIAVGNEISPVTGTSYLTSFLTPAMVNI 150
>PUTA_KLEAE (O52485) Bifunctional protein putA [Includes: Proline dehydrogenase| (EC 1.5.99.8) (Proline oxidase); Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) (P5C dehydrogenase)] Length = 1312 Score = 29.6 bits (65), Expect = 7.7 Identities = 23/71 (32%), Positives = 33/71 (46%) Frame = +3 Query: 210 VRLLRDNEAEVRIAAAGKVTKFCRILSPQLAIQHILPCVKELSSDSSQHVRSALASVIMG 389 V + DNE + I A + C +L P A+Q L K+L + S+ +R A A + Sbjct: 1193 VLCVADNEQDALIQLAAVLAVGCEVLWPDSALQRDL--AKKLPREVSERIRFAKAEQL-- 1248 Query: 390 MAPVLGKDATI 422 PV DA I Sbjct: 1249 --PVQAFDAVI 1257
>YAT2_SCHPO (Q10149) Hypothetical protein C1D4.02c in chromosome I| Length = 345 Score = 29.6 bits (65), Expect = 7.7 Identities = 17/67 (25%), Positives = 35/67 (52%), Gaps = 5/67 (7%) Frame = +3 Query: 438 IFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAE-----DRHWRVRLA 602 +F++LL+D P+V L + S Q+ + + I + S + +++ A D W + L Sbjct: 66 MFMALLRDSSPEVTLEVFSLKGQITRKVNIKINSDEKIGMVLQWASIAPAVDAIWHI-LN 124 Query: 603 IIEYIPL 623 +I+ P+ Sbjct: 125 VIDDSPV 131
>HEATR_HUMAN (Q9H583) HEAT repeat-containing protein 1 (Protein BAP28)| Length = 2144 Score = 29.6 bits (65), Expect = 7.7 Identities = 22/100 (22%), Positives = 41/100 (41%), Gaps = 22/100 (22%) Frame = +3 Query: 306 QHILPCVKELS--------------------SDSSQHVRSALASVIMGMAPVLGKD--AT 419 +H++PC+ + S DSS VR A ++ +A L ++ Sbjct: 2043 KHLIPCIAQFSVAMADDSLWKPLNYQILLKTRDSSPKVRFAALITVLALAEKLKENYIVL 2102 Query: 420 IEQLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLS 539 + + +P L++DE +V + Q+ V+G L S Sbjct: 2103 LPESIPFLAELMEDECEEVEHQCQKTIQQLETVLGEPLQS 2142 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 91,186,555 Number of Sequences: 219361 Number of extensions: 1843411 Number of successful extensions: 5008 Number of sequences better than 10.0: 48 Number of HSP's better than 10.0 without gapping: 4657 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4913 length of database: 80,573,946 effective HSP length: 107 effective length of database: 57,102,319 effective search space used: 5824436538 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
