ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | baal4g19 |
|---|---|
| Clone Library Name | barley_pub |
>DHGY_CUCSA (P13443) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-dependent| hydroxypyruvate reductase) (HPR) (GDH) Length = 382 Score = 340 bits (871), Expect = 2e-93 Identities = 164/198 (82%), Positives = 175/198 (88%) Frame = +1 Query: 13 MAKPISIEVWNPSGKYRVVSTKSMPGTRWIKLLTDNDCRLEICTEKKTILSVDDILALIG 192 MAKP+ IEVWNP+GKYRVVSTK MPGTRWI LL + DCR+EICTEKKTILSV+DILALIG Sbjct: 1 MAKPVQIEVWNPNGKYRVVSTKPMPGTRWINLLIEQDCRVEICTEKKTILSVEDILALIG 60 Query: 193 DHCHGVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLT 372 D C GVIGQLTEDWGEVLFSAL RAGG AFSNMAVGYNNVDV+AANK G+A+GNTPGVLT Sbjct: 61 DKCDGVIGQLTEDWGEVLFSALSRAGGKAFSNMAVGYNNVDVNAANKYGVAVGNTPGVLT 120 Query: 373 ETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 552 ETT RRIVEAD+FMRAG YDGWLP+LFVGNLLKGQTVGVIGAGRIGSAY Sbjct: 121 ETTAELAASLSLAAARRIVEADEFMRAGRYDGWLPNLFVGNLLKGQTVGVIGAGRIGSAY 180 Query: 553 ARMMIEGFKMNLIYFDLY 606 ARMM+EGFKMNLIYFDLY Sbjct: 181 ARMMVEGFKMNLIYFDLY 198
>GYAR_THELI (Q9C4M5) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 331 Score = 98.2 bits (243), Expect = 2e-20 Identities = 50/106 (47%), Positives = 69/106 (65%), Gaps = 4/106 (3%) Frame = +1 Query: 292 AVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYD-- 465 AVGY+N+D++ A K GI + NTPGVLT+ T RRIVEAD F+R+G + Sbjct: 75 AVGYDNIDIEEATKRGIYVTNTPGVLTDATADLAFALLLAVARRIVEADAFVRSGEWKKS 134 Query: 466 --GWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYF 597 GW P +F+G LKG+T+G++G GRIG A A+ +GF M +IY+ Sbjct: 135 EVGWHPLMFLGYGLKGKTLGIVGFGRIGQALAK-RAKGFGMKIIYY 179
>GYAR_AERPE (Q9YAW4) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 335 Score = 90.5 bits (223), Expect = 3e-18 Identities = 48/108 (44%), Positives = 67/108 (62%), Gaps = 4/108 (3%) Frame = +1 Query: 283 SNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAG-- 456 + MAVG++N+DV+ A + GI + NTPGVLTE T RR+VEAD F+R G Sbjct: 73 AQMAVGFDNIDVECATRLGIYVTNTPGVLTEATAEFTWALILAAARRVVEADHFVRWGEW 132 Query: 457 --LYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIY 594 L GW P + +G L+G+T+G++G GRIGS A + + F M +IY Sbjct: 133 WRLRTGWHPMMMLGVELRGKTLGILGMGRIGSRVAEIG-KAFGMRIIY 179
>GYAR_PYRKO (Q5JEZ2) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 333 Score = 90.1 bits (222), Expect = 4e-18 Identities = 51/134 (38%), Positives = 74/134 (55%), Gaps = 4/134 (2%) Frame = +1 Query: 208 VIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXX 387 ++ L+E +F A R A N AVGY+N+DV+ A + GI + NTP VLT+ T Sbjct: 49 LVTMLSERIDSEVFDAAPRLRIVA--NYAVGYDNIDVEEATRRGIYVTNTPDVLTDATAD 106 Query: 388 XXXXXXXXXXRRIVEADQFMRAGLYD----GWLPHLFVGNLLKGQTVGVIGAGRIGSAYA 555 RR++EAD F R+G + W P F+G + G+T+G++G GRIG A A Sbjct: 107 FAWTLLLATARRLIEADHFTRSGEWKRRGIAWHPRWFLGYDVYGKTIGIVGFGRIGQAVA 166 Query: 556 RMMIEGFKMNLIYF 597 R GF M ++Y+ Sbjct: 167 R-RARGFGMRILYY 179
>GYAR_PYRAB (Q9UYR1) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 335 Score = 89.0 bits (219), Expect = 1e-17 Identities = 45/109 (41%), Positives = 65/109 (59%), Gaps = 4/109 (3%) Frame = +1 Query: 283 SNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLY 462 +N AVGY+N+DV+ A K GI + NTPGVLT+ T R +V+ D+F R+G + Sbjct: 73 ANYAVGYDNIDVEEATKRGIYVTNTPGVLTDATADLAFALLLATARHLVKGDKFTRSGEW 132 Query: 463 D----GWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYF 597 W P F+G + G+T+G+IG GRIG A A+ GF M ++Y+ Sbjct: 133 KKRGVAWHPKWFLGYDVYGKTIGIIGFGRIGQAIAK-RARGFDMRILYY 180
>GYAR_PYRHO (O58320) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 334 Score = 89.0 bits (219), Expect = 1e-17 Identities = 60/185 (32%), Positives = 98/185 (52%), Gaps = 4/185 (2%) Frame = +1 Query: 55 KYRVVSTKSMPGTRWIKLLTDNDCRLEICTEKKTILSVDDILALIGDHCHGVIGQLTEDW 234 K +V T+ +P IK+L D + +E+ ++K I +IL ++ L+E Sbjct: 2 KPKVFITREIPEVG-IKMLED-EFEVEVWGDEKEIPR--EILLKKVKEVDALVTMLSERI 57 Query: 235 GEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXX 414 + +F + A N AVGY+N+D++ A K GI + NTP VLT+ T Sbjct: 58 DKEVFENAPKLRIVA--NYAVGYDNIDIEEATKRGIYVTNTPDVLTDATADLAFALLLAT 115 Query: 415 XRRIVEADQFMRAGLYD----GWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKM 582 R +V+ D+F+R+G + W P F+G + G+T+G+IG GRIG A A+ +GF M Sbjct: 116 ARHVVKGDRFVRSGEWKKRGVAWHPKWFLGYDVYGKTIGIIGLGRIGQAIAK-RAKGFNM 174 Query: 583 NLIYF 597 ++Y+ Sbjct: 175 RILYY 179
>GYAR_PYRFU (Q8U3Y2) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 336 Score = 89.0 bits (219), Expect = 1e-17 Identities = 60/185 (32%), Positives = 99/185 (53%), Gaps = 4/185 (2%) Frame = +1 Query: 55 KYRVVSTKSMPGTRWIKLLTDNDCRLEICTEKKTILSVDDILALIGDHCHGVIGQLTEDW 234 K +V T+++P I +L + + +E+ E++ I + +L + D ++ L+E Sbjct: 2 KPKVFITRAIP-ENGINML-EEEFEVEVWEEEREIPR-EKLLEKVKD-VDALVTMLSERI 57 Query: 235 GEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXX 414 + +F R A N AVGY+N+DV+ A + GI + NTP VLT T Sbjct: 58 DQEVFENAPRLRIVA--NYAVGYDNIDVEEATRRGIYVTNTPDVLTNATADHAFALLLAT 115 Query: 415 XRRIVEADQFMRAGLYD----GWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKM 582 R +V+ D+F+R+G + W P F+G L G+T+G++G GRIG A AR +GF M Sbjct: 116 ARHVVKGDKFVRSGEWKRKGIAWHPKWFLGYELYGKTIGIVGFGRIGQAIAR-RAKGFNM 174 Query: 583 NLIYF 597 ++Y+ Sbjct: 175 RILYY 179
>TKRA_BACSU (O32264) Probable 2-ketogluconate reductase (EC 1.1.1.215) (2KR)| Length = 325 Score = 79.3 bits (194), Expect = 8e-15 Identities = 51/164 (31%), Positives = 73/164 (44%), Gaps = 22/164 (13%) Frame = +1 Query: 169 DDILALIGDHCHGVIGQLTEDWGEVLFSALKRAGGT----------------------AF 282 ++I A IG+HC + Q +VLF LK A G Sbjct: 14 EEIEAFIGEHCRYEVWQEDTLPSDVLFEKLKEAEGLLTSGTSGPSINRELLEHAPKLKVV 73 Query: 283 SNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLY 462 SN +VGY+N D++A + G+ +TP L +T RR+ E D+F+RAG + Sbjct: 74 SNQSVGYDNFDIEAMKERGVVGTHTPYTLDDTVADLAFSLILSSARRVAELDRFVRAGKW 133 Query: 463 DGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIY 594 G + QT+G+IG GRIG AR GF M ++Y Sbjct: 134 GTVEEEALFGIDVHHQTLGIIGMGRIGEQAARRAKFGFDMEVLY 177
>GRHPR_MOUSE (Q91Z53) Glyoxylate reductase/hydroxypyruvate reductase (EC| 1.1.1.79) Length = 328 Score = 75.5 bits (184), Expect = 1e-13 Identities = 52/173 (30%), Positives = 80/173 (46%) Frame = +1 Query: 46 PSGKYRVVSTKSMPGTRWIKLLTDNDCRLEICTEKKTILSVDDILALIGDHCHGVIGQLT 225 P+ +V T +P L DC +E I D ++G HG++ +L+ Sbjct: 3 PARLMKVFVTGPLPAEGRAALAQAADCEVEQWNSDDPIPRKDLEQGVVG--AHGLLCRLS 60 Query: 226 EDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXX 405 + + L A A S ++VG +++ +D K GI +G TPGVLT+ T Sbjct: 61 DRVDKKLLDAAG-ANLRVISTLSVGVDHLALDEIKKRGIRVGYTPGVLTDATAELAVSLL 119 Query: 406 XXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMM 564 RR+ EA + ++ G + W P G L TVG++G GRIG A AR + Sbjct: 120 LTTCRRLPEAIEEVKNGGWSSWSPLWMCGYGLSQSTVGIVGLGRIGQAIARRL 172
>DHGY_HYPME (P36234) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-dependent| hydroxypyruvate reductase) (HPR) (GDH) (Hydroxypyruvate dehydrogenase) (Glyoxylate reductase) Length = 321 Score = 73.9 bits (180), Expect = 3e-13 Identities = 47/164 (28%), Positives = 78/164 (47%), Gaps = 1/164 (0%) Frame = +1 Query: 118 NDCRLEICTEKKTILSVDDILALIGDHCHG-VIGQLTEDWGEVLFSALKRAGGTAFSNMA 294 +D ++ I +T SVD +L + + C VI ++ E+ S + Sbjct: 30 DDPKITIDEMIETAKSVDALLITLNEKCRKEVIDRIPENI-------------KCISTYS 76 Query: 295 VGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 474 +G++++D+DA GI +GN P +T T RR E ++ +R + GW Sbjct: 77 IGFDHIDLDACKARGIKVGNAPHGVTVATAEIAMLLLLGSARRAGEGEKMIRTRSWPGWE 136 Query: 475 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLY 606 P VG L +T+G+ G G IG A A+ +GF M++ YFD + Sbjct: 137 PLELVGEKLDNKTLGIYGFGSIGQALAK-RAQGFDMDIDYFDTH 179
>GRHPR_HUMAN (Q9UBQ7) Glyoxylate reductase/hydroxypyruvate reductase (EC| 1.1.1.79) Length = 328 Score = 73.2 bits (178), Expect = 6e-13 Identities = 51/168 (30%), Positives = 80/168 (47%) Frame = +1 Query: 61 RVVSTKSMPGTRWIKLLTDNDCRLEICTEKKTILSVDDILALIGDHCHGVIGQLTEDWGE 240 +V T+ +P + L DC +E + I + + + G HG++ L++ + Sbjct: 8 KVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAG--AHGLLCLLSDHVDK 65 Query: 241 VLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXR 420 + A A S M+VG +++ +D K GI +G TP VLT+TT R Sbjct: 66 RILDAAG-ANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCR 124 Query: 421 RIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMM 564 R+ EA + ++ G + W P G L TVG+IG GRIG A AR + Sbjct: 125 RLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRL 172
>TKRA_ECOLI (P37666) 2-ketogluconate reductase (EC 1.1.1.215) (2KR)| (2-ketoaldonate reductase) Length = 324 Score = 69.3 bits (168), Expect = 8e-12 Identities = 38/106 (35%), Positives = 58/106 (54%) Frame = +1 Query: 277 AFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAG 456 A S ++VGY+N DVDA I + +TP VLTET RR+VE + ++AG Sbjct: 69 ATSTISVGYDNFDVDALTARKILLMHTPTVLTETVADTLMALVLSTARRVVEVAERVKAG 128 Query: 457 LYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIY 594 + + + G + +T+G++G GRIG A A+ GF M ++Y Sbjct: 129 EWTASIGPDWYGTDVHHKTLGIVGMGRIGMALAQRAHFGFNMPILY 174
>TKRA_ECO57 (P58220) 2-ketogluconate reductase (EC 1.1.1.215) (2KR)| (2-ketoaldonate reductase) Length = 324 Score = 69.3 bits (168), Expect = 8e-12 Identities = 38/106 (35%), Positives = 58/106 (54%) Frame = +1 Query: 277 AFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAG 456 A S ++VGY+N DVDA I + +TP VLTET RR+VE + ++AG Sbjct: 69 ATSTISVGYDNFDVDALTARKILLMHTPTVLTETVADTLMALVLSTARRVVEVAERVKAG 128 Query: 457 LYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIY 594 + + + G + +T+G++G GRIG A A+ GF M ++Y Sbjct: 129 EWTASIGPDWYGTDVHHKTLGIVGMGRIGMALAQRAHFGFNMPILY 174
>TKRA_ENTAG (P58000) 2-ketogluconate reductase (EC 1.1.1.215) (2KR)| (2-ketoaldonate reductase) Length = 323 Score = 68.9 bits (167), Expect = 1e-11 Identities = 38/106 (35%), Positives = 60/106 (56%) Frame = +1 Query: 277 AFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAG 456 A S ++VGY+N DV+A N+ GI + +TP VLTET RR+VE + ++AG Sbjct: 68 AASTISVGYDNFDVEALNQRGIVLIDTPTVLTETVADTMMALVLSSARRVVEVAERVKAG 127 Query: 457 LYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIY 594 + + + G + + +G++G GRIG A A+ GF M ++Y Sbjct: 128 EWRRSIGPDWFGIDVHHKKMGILGMGRIGLALAQRAHHGFGMPILY 173
>SERA_ARCFU (O29445) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 527 Score = 65.1 bits (157), Expect = 2e-10 Identities = 47/154 (30%), Positives = 80/154 (51%), Gaps = 2/154 (1%) Frame = +1 Query: 145 EKKTILSVDDILALIGDHCHGVIGQLTEDWGEVLFSA--LKRAGGTAFSNMAVGYNNVDV 318 E KT +S ++++ + + V+ T+ EV+ +A LK G VG +N+D+ Sbjct: 25 EVKTGMSREELIREVPKYEAIVVRSQTKVDAEVIQAAKNLKIIG-----RAGVGVDNIDI 79 Query: 319 DAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNL 498 +AA + GI + N PG T +T R+I +AD+ ++ G W F+G Sbjct: 80 NAATQRGIVVVNAPGGNTISTAEHAIALMLAAARKIPQADRSVKEG---KWERKKFMGIE 136 Query: 499 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFD 600 L+G+T GVIG GR+G A+ + +MN++ +D Sbjct: 137 LRGKTAGVIGLGRVGFEVAK-RCKALEMNVLAYD 169
>YGDH_SCHPO (O94574) Putative 2-hydroxyacid dehydrogenase C1773.17c (EC| 1.-.-.-) Length = 340 Score = 61.6 bits (148), Expect = 2e-09 Identities = 36/96 (37%), Positives = 51/96 (53%) Frame = +1 Query: 280 FSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGL 459 F A GYNNVDVD A +NG+ + NTP TE T R EA+Q +R G Sbjct: 87 FVTGAAGYNNVDVDWATRNGVYVANTPNGPTEGTANMNLMLFMCTLRGAREAEQSLRLG- 145 Query: 460 YDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMI 567 W +L + + G+ VG+IG G IG ++A+ ++ Sbjct: 146 --KWRQNLSLTDDPYGKRVGIIGMGAIGKSFAQKIL 179
>SERA_MYCLE (O33116) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 528 Score = 60.8 bits (146), Expect = 3e-09 Identities = 38/104 (36%), Positives = 51/104 (49%) Frame = +1 Query: 295 VGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 474 VG +NVDVDAA G+ + N P + R+I EAD +RA + W Sbjct: 74 VGLDNVDVDAATARGVLVVNAPTSNIHSAAEHALALLLAASRQIAEADASLRAHI---WK 130 Query: 475 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLY 606 F G + G+TVGV+G GRIG A I F ++I +D Y Sbjct: 131 RSSFSGTEIFGKTVGVVGLGRIGQLVA-ARIAAFGAHVIAYDPY 173
>SERA_METTH (O27051) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 525 Score = 60.8 bits (146), Expect = 3e-09 Identities = 45/151 (29%), Positives = 74/151 (49%) Frame = +1 Query: 154 TILSVDDILALIGDHCHGVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANK 333 T ++ +++L I D V+ T+ EV+ +A + + VG +NVDV AA Sbjct: 30 TTITPEELLDAIKDFDAIVVRSRTKVTREVIEAAPRLK---IIARAGVGVDNVDVKAATD 86 Query: 334 NGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQT 513 GI + N P + T R+I AD+ ++ G W + F+G L G+T Sbjct: 87 RGIMVINAPESTSITVAEHSIGLMLALARKIAIADRSVKEG---KWEKNRFMGIELNGKT 143 Query: 514 VGVIGAGRIGSAYARMMIEGFKMNLIYFDLY 606 +G+IG GRIGS + + F M+++ +D Y Sbjct: 144 LGIIGMGRIGSQVV-VRTKAFGMDIMVYDPY 173
>LDHD_ECOLI (P52643) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH)| (Fermentative lactate dehydrogenase) Length = 329 Score = 60.1 bits (144), Expect = 5e-09 Identities = 44/136 (32%), Positives = 62/136 (45%) Frame = +1 Query: 199 CHGVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTET 378 C V + +D + LK+ G + G+NNVD+DAA + G+ + P E Sbjct: 45 CEAVCIFVNDDGSRPVLEELKKHGVKYIALRCAGFNNVDLDAAKELGLKVVRVPAYDPEA 104 Query: 379 TXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYAR 558 RRI A Q R + L L G + G+T GVIG G+IG A R Sbjct: 105 VAEHAIGMMMTLNRRIHRAYQRTRDANFS--LEGL-TGFTMYGKTAGVIGTGKIGVAMLR 161 Query: 559 MMIEGFKMNLIYFDLY 606 +++GF M L+ FD Y Sbjct: 162 -ILKGFGMRLLAFDPY 176
>PTXD_PSEST (O69054) Phosphonate dehydrogenase (EC 1.20.1.1) (NAD-dependent| phosphite dehydrogenase) Length = 336 Score = 59.7 bits (143), Expect = 6e-09 Identities = 35/101 (34%), Positives = 50/101 (49%) Frame = +1 Query: 298 GYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 477 G++N DVDA G+ + P +LT T R + AD F+R+G + GW P Sbjct: 77 GFDNFDVDACTARGVWLTFVPDLLTVPTAELAIGLAVGLGRHLRAADAFVRSGEFQGWQP 136 Query: 478 HLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFD 600 F G L TVG++G G IG A A ++G+ L Y + Sbjct: 137 Q-FYGTGLDNATVGILGMGAIGLAMAD-RLQGWGATLQYHE 175
>SERA_ARATH (O04130) D-3-phosphoglycerate dehydrogenase, chloroplast precursor| (EC 1.1.1.95) (3-PGDH) Length = 624 Score = 59.7 bits (143), Expect = 6e-09 Identities = 52/194 (26%), Positives = 86/194 (44%), Gaps = 5/194 (2%) Frame = +1 Query: 40 WNPS-GKYRVVSTKSM--PGTRWIKLLTDNDCRLEICTE--KKTILSVDDILALIGDHCH 204 +NP+ K R++ T+ + G ++ D DC ++ E KK + D ++ G Sbjct: 76 YNPTLPKPRILVTEKLGEAGVNLLREFGDVDCSYDLSPEDLKKKVAESDALIVRSGT--- 132 Query: 205 GVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTX 384 ++T + E LK G VG +NVD+ AA ++G + N P T Sbjct: 133 ----KVTREVFEAAKGRLKVVG-----RAGVGIDNVDLQAATEHGCLVVNAPTANTVAAA 183 Query: 385 XXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMM 564 R + +AD ++AG W +VG L G+T+ V+G G++G+ AR Sbjct: 184 EHGIALLASMARNVAQADASIKAG---KWERSKYVGVSLVGKTLAVMGFGKVGTEVAR-R 239 Query: 565 IEGFKMNLIYFDLY 606 +G M +I D Y Sbjct: 240 AKGLGMTVISHDPY 253
>DDH_HAEIN (P44501) 2-hydroxyacid dehydrogenase homolog (EC 1.1.1.-)| Length = 331 Score = 58.5 bits (140), Expect = 1e-08 Identities = 42/138 (30%), Positives = 64/138 (46%) Frame = +1 Query: 187 IGDHCHGVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGV 366 + +HC V + ++ + L G + G+NNVD+ AA + GI + P Sbjct: 41 LAEHCEVVCIFVNDNGSRKVLEKLAALGVKIVALRCAGFNNVDLKAAQELGIQVVRVPAY 100 Query: 367 LTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGS 546 E RRI A Q R + L L +G + G+TVGVIG G+IG Sbjct: 101 SPEAVAEHTIGLMMTLNRRIHRAYQRTREANFS--LEGL-IGFNMYGRTVGVIGTGKIGI 157 Query: 547 AYARMMIEGFKMNLIYFD 600 A R +++GF MN++ +D Sbjct: 158 AVMR-ILKGFGMNILAYD 174
>SERA_HUMAN (O43175) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 58.2 bits (139), Expect = 2e-08 Identities = 45/152 (29%), Positives = 74/152 (48%), Gaps = 1/152 (0%) Frame = +1 Query: 148 KKTILSVDDILALIGDHCHG-VIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDA 324 +K LS ++++A + D C G ++ T+ +V+ +A K G +NVD++A Sbjct: 31 EKQNLSKEELIAELQD-CEGLIVRSATKVTADVINAAEKLQ---VVGRAGTGVDNVDLEA 86 Query: 325 ANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLK 504 A + GI + NTP + + R+I +A M+ G W F+G L Sbjct: 87 ATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGK---WERKKFMGTELN 143 Query: 505 GQTVGVIGAGRIGSAYARMMIEGFKMNLIYFD 600 G+T+G++G GRIG A M + F M I +D Sbjct: 144 GKTLGILGLGRIGREVATRM-QSFGMKTIGYD 174
>SERA_MOUSE (Q61753) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| (A10) Length = 532 Score = 57.8 bits (138), Expect = 2e-08 Identities = 44/152 (28%), Positives = 75/152 (49%), Gaps = 1/152 (0%) Frame = +1 Query: 148 KKTILSVDDILALIGDHCHG-VIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDA 324 +K LS ++++A + D C G ++ T+ +V+ +A K G +NVD++A Sbjct: 31 EKQNLSKEELIAELQD-CEGLIVRSATKVTADVINAAEKLQ---VVGRAGTGVDNVDLEA 86 Query: 325 ANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLK 504 A + GI + NTP + + R+I +A M+ G +D F+G L Sbjct: 87 ATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWDR---KKFMGTELN 143 Query: 505 GQTVGVIGAGRIGSAYARMMIEGFKMNLIYFD 600 G+T+G++G GRIG A M + F M + +D Sbjct: 144 GKTLGILGLGRIGREVATRM-QSFGMKTVGYD 174
>SERA_MACFA (Q60HD7) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 57.8 bits (138), Expect = 2e-08 Identities = 44/152 (28%), Positives = 74/152 (48%), Gaps = 1/152 (0%) Frame = +1 Query: 148 KKTILSVDDILALIGDHCHG-VIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDA 324 +K LS ++++A + D C G ++ T+ +V+ +A K G +NVD++A Sbjct: 31 EKQNLSKEELIAELQD-CEGLIVRSATKVTADVINAAEKLQ---VVGRAGTGVDNVDLEA 86 Query: 325 ANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLK 504 A + G+ + NTP + + R+I +A M+ G W F+G L Sbjct: 87 ATRKGVLVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGK---WERKKFMGTELN 143 Query: 505 GQTVGVIGAGRIGSAYARMMIEGFKMNLIYFD 600 G+T+G++G GRIG A M + F M I +D Sbjct: 144 GKTLGILGLGRIGREVATRM-QSFGMKTIGYD 174
>LDHD_PEDAC (Q59642) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 331 Score = 57.4 bits (137), Expect = 3e-08 Identities = 45/134 (33%), Positives = 59/134 (44%) Frame = +1 Query: 205 GVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTX 384 GV+ + + LF + G AFS VG +NV DA KN I I N P Sbjct: 47 GVVAYQQKPYTADLFDKMHEFGIHAFSLRNVGLDNVPADALKKNDIKISNVPAYSPRAIA 106 Query: 385 XXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMM 564 R+I E + M G Y W P +G L TVGVIG GRIG A A + Sbjct: 107 ELSVTQLLALLRKIPEFEYKMAHGDY-RWEPD--IGLELNQMTVGVIGTGRIGRA-AIDI 162 Query: 565 IEGFKMNLIYFDLY 606 + F +I +D++ Sbjct: 163 FKPFGAKVIAYDVF 176
>SERA_RAT (O08651) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 57.4 bits (137), Expect = 3e-08 Identities = 43/152 (28%), Positives = 75/152 (49%), Gaps = 1/152 (0%) Frame = +1 Query: 148 KKTILSVDDILALIGDHCHG-VIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDA 324 +K LS ++++A + D C G ++ T+ +V+ +A K G +NVD++A Sbjct: 31 EKQNLSKEELIAELQD-CEGLIVRSATKVTADVINAAEKLQ---VVGRAGTGVDNVDLEA 86 Query: 325 ANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLK 504 A + G+ + NTP + + R+I +A M+ G +D F+G L Sbjct: 87 ATRKGVLVMNTPNGNSLSAAELTCGMLMCLARQIPQATASMKDGKWDR---KKFMGTELN 143 Query: 505 GQTVGVIGAGRIGSAYARMMIEGFKMNLIYFD 600 G+T+G++G GRIG A M + F M + +D Sbjct: 144 GKTLGILGLGRIGREVAARM-QAFGMKTVGYD 174
>SERA_METJA (Q58424) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 524 Score = 56.2 bits (134), Expect = 7e-08 Identities = 46/154 (29%), Positives = 70/154 (45%) Frame = +1 Query: 145 EKKTILSVDDILALIGDHCHGVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDA 324 E T L+ +++L I D V+ T+ +V+ A K VG +N+DV+A Sbjct: 25 EVATGLTKEELLEKIKDADVLVVRSGTKVTRDVIEKAEKLK---VIGRAGVGVDNIDVEA 81 Query: 325 ANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLK 504 A + GI + N P + + R I +A ++ G W F G L Sbjct: 82 ATEKGIIVVNAPDASSISVAELTMGLMLAAARNIPQATASLKRG---EWDRKRFKGIELY 138 Query: 505 GQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLY 606 G+T+GVIG GRIG + + F MN+I +D Y Sbjct: 139 GKTLGVIGLGRIGQQVVK-RAKAFGMNIIGYDPY 171
>CTBPB_XENLA (Q9W758) C-terminal-binding protein B (TCF-3 corepressor CtBP)| (XCtBP) Length = 437 Score = 56.2 bits (134), Expect = 7e-08 Identities = 51/187 (27%), Positives = 82/187 (43%), Gaps = 12/187 (6%) Frame = +1 Query: 82 MPGTRWIKLLTDNDCRLEICTEKKTILSVDDILALIGDHCHGVIGQLTEDWGEVLFSA-- 255 MP + LL DC +E+ K + +V A H + L+E G +++ Sbjct: 27 MPVRPLVALLDGRDCTIEMPI-LKDVATVAFCDAQSTQEIHEKV--LSEAVGALMYHTIT 83 Query: 256 LKRAGGTAFSNMAV------GYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXX 417 L R F + + GY+N+D+ +A + GIA+ N P E T Sbjct: 84 LSREDLEKFKALRIIIKIGSGYDNIDIKSAAELGIAVCNIPSASVEETADSTLCHILNLY 143 Query: 418 RRIVEADQFMRAGLYDGWLPHL--FVGNL--LKGQTVGVIGAGRIGSAYARMMIEGFKMN 585 RR+ Q MR G + + G ++G+T+G+IG GRIG A A + + F Sbjct: 144 RRVTWLHQAMREGNRPASVEQIREVAGGAARIRGETLGIIGLGRIGQAVA-LRAKAFNFT 202 Query: 586 LIYFDLY 606 +I++D Y Sbjct: 203 VIFYDPY 209
>SERA_PONPY (Q5R7M2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 55.5 bits (132), Expect = 1e-07 Identities = 44/146 (30%), Positives = 71/146 (48%), Gaps = 2/146 (1%) Frame = +1 Query: 148 KKTILSVDDILALIGDHCHG-VIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDA 324 +K LS ++++A + D C G ++ T+ +V+ +A K G +NVD++A Sbjct: 31 EKQNLSKEELIAELQD-CEGLIVRSATKVTADVINAAEKLQ---VVGRAGTGVDNVDLEA 86 Query: 325 ANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLK 504 A + GI + NTP + + R+I +A M+ G W F+G L Sbjct: 87 ATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGK---WERKKFMGTELN 143 Query: 505 GQTVGVIGAGRIGSAYA-RMMIEGFK 579 G+T+G++G GRIG A RM G K Sbjct: 144 GKTLGILGLGRIGREVAIRMQSLGMK 169
>SERA_BOVIN (Q5EAD2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 55.5 bits (132), Expect = 1e-07 Identities = 43/152 (28%), Positives = 73/152 (48%), Gaps = 1/152 (0%) Frame = +1 Query: 148 KKTILSVDDILALIGDHCHG-VIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDA 324 +K LS ++++A + D C G ++ T+ +++ +A K G +NVD++A Sbjct: 31 EKQNLSKEELIAELQD-CEGLIVRSATKVTSDIINAAEKLQ---VVGRAGTGVDNVDLEA 86 Query: 325 ANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLK 504 A + GI + NTP + + R+I +A M+ G W F+G L Sbjct: 87 ATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQAAASMKDGK---WERKKFMGTELN 143 Query: 505 GQTVGVIGAGRIGSAYARMMIEGFKMNLIYFD 600 G+ +G++G GRIG A M + F M I +D Sbjct: 144 GKVLGILGLGRIGREVATRM-QSFGMKTIGYD 174
>LDHD_LACHE (P30901) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 336 Score = 55.1 bits (131), Expect = 2e-07 Identities = 41/134 (30%), Positives = 59/134 (44%) Frame = +1 Query: 205 GVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTX 384 GV+ D+ AL AG T S VG +N+D+D A + G I N P Sbjct: 48 GVVVYQQLDYTADTLQALADAGVTKMSLRNVGVDNIDMDKAKELGFQITNVPVYSPNAIA 107 Query: 385 XXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMM 564 R+ D+ M A W P +G ++ Q VGV+G G IG + R+M Sbjct: 108 EHAAIQAARVLRQDKRMDEKM-AKRDLRWAP--TIGREVRDQVVGVVGTGHIGQVFMRIM 164 Query: 565 IEGFKMNLIYFDLY 606 EGF +I +D++ Sbjct: 165 -EGFGAKVIAYDIF 177
>SERA_MYCTU (P0A544) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 528 Score = 55.1 bits (131), Expect = 2e-07 Identities = 44/146 (30%), Positives = 64/146 (43%) Frame = +1 Query: 169 DDILALIGDHCHGVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAI 348 D +LA + + ++ T EVL +A K + VG +NVDVDAA G+ + Sbjct: 35 DKLLAAVPEADALLVRSATTVDAEVLAAAPKLK---IVARAGVGLDNVDVDAATARGVLV 91 Query: 349 GNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIG 528 N P + R+I AD +R W F G + G+TVGV+G Sbjct: 92 VNAPTSNIHSAAEHALALLLAASRQIPAADASLRE---HTWKRSSFSGTEIFGKTVGVVG 148 Query: 529 AGRIGSAYARMMIEGFKMNLIYFDLY 606 GRIG A+ I F ++ +D Y Sbjct: 149 LGRIGQLVAQ-RIAAFGAYVVAYDPY 173
>SERA_MYCBO (P0A545) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 528 Score = 55.1 bits (131), Expect = 2e-07 Identities = 44/146 (30%), Positives = 64/146 (43%) Frame = +1 Query: 169 DDILALIGDHCHGVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAI 348 D +LA + + ++ T EVL +A K + VG +NVDVDAA G+ + Sbjct: 35 DKLLAAVPEADALLVRSATTVDAEVLAAAPKLK---IVARAGVGLDNVDVDAATARGVLV 91 Query: 349 GNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIG 528 N P + R+I AD +R W F G + G+TVGV+G Sbjct: 92 VNAPTSNIHSAAEHALALLLAASRQIPAADASLRE---HTWKRSSFSGTEIFGKTVGVVG 148 Query: 529 AGRIGSAYARMMIEGFKMNLIYFDLY 606 GRIG A+ I F ++ +D Y Sbjct: 149 LGRIGQLVAQ-RIAAFGAYVVAYDPY 173
>SERA_BACSU (P35136) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 525 Score = 54.3 bits (129), Expect = 3e-07 Identities = 33/102 (32%), Positives = 53/102 (51%) Frame = +1 Query: 295 VGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 474 VG +N+D+D A K+G+ + N P T +T R I +A+ +++ W Sbjct: 71 VGVDNIDIDEATKHGVIVINAPNGNTISTAEHTFAMISSLMRHIPQANISVKSR---EWN 127 Query: 475 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFD 600 +VG+ L G+T+G++G GRIGS A+ F M + FD Sbjct: 128 RTAYVGSELYGKTLGIVGLGRIGSEIAQRR-GAFGMTVHVFD 168
>DDH_ZYMMO (P30799) 2-hydroxyacid dehydrogenase homolog (EC 1.1.1.-)| Length = 331 Score = 50.8 bits (120), Expect = 3e-06 Identities = 34/106 (32%), Positives = 47/106 (44%), Gaps = 6/106 (5%) Frame = +1 Query: 298 GYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRI------VEADQFMRAGL 459 GYNNVD+DAA K I + P + R+I V + F GL Sbjct: 78 GYNNVDLDAAKKLNIKVVRVPAYSPYSVAEYAVGMLLTLNRQISRGLKRVRENNFSLEGL 137 Query: 460 YDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYF 597 +G + +TVG+IG G IGS +A +M GF N+I + Sbjct: 138 ---------IGLDVHDKTVGIIGVGHIGSVFAHIMTHGFGANVIAY 174
>LDHD_STRA5 (Q8E0N5) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 50.4 bits (119), Expect = 4e-06 Identities = 34/134 (25%), Positives = 59/134 (44%) Frame = +1 Query: 205 GVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTX 384 G+ E + ++ LK G + + G + +++ A ++GI I N P E+ Sbjct: 47 GIANAQIEPLDDAIYPLLKEMGIKQIAQRSAGVDMYNLELAKQHGIIISNVPSYSPESIA 106 Query: 385 XXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMM 564 R++ +R + LP G +L TV +IG GRIG A A+ + Sbjct: 107 EFTVTIALNLIRKVELIRANVREQNFSWTLP--IRGRVLGNMTVAIIGTGRIGLATAK-I 163 Query: 565 IEGFKMNLIYFDLY 606 +GF +I +D+Y Sbjct: 164 FKGFGCRVIGYDIY 177
>CTBP1_MOUSE (O88712) C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1)| Length = 440 Score = 50.4 bits (119), Expect = 4e-06 Identities = 30/107 (28%), Positives = 51/107 (47%), Gaps = 4/107 (3%) Frame = +1 Query: 298 GYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 477 G++N+D+ +A GIA+ N P E T RR Q +R G + Sbjct: 101 GFDNIDIKSAGDLGIAVCNVPAASVEETADSTLCHILNLYRRTTWLHQALREGTRVQSVE 160 Query: 478 HL----FVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLY 606 + ++G+T+G+IG GR+G A A + + F N++++D Y Sbjct: 161 QIREVASGAARIRGETLGIIGLGRVGQAVA-LRAKAFGFNVLFYDPY 206
>CTBP1_HUMAN (Q13363) C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1)| Length = 440 Score = 50.4 bits (119), Expect = 4e-06 Identities = 30/107 (28%), Positives = 51/107 (47%), Gaps = 4/107 (3%) Frame = +1 Query: 298 GYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 477 G++N+D+ +A GIA+ N P E T RR Q +R G + Sbjct: 101 GFDNIDIKSAGDLGIAVCNVPAASVEETADSTLCHILNLYRRATWLHQALREGTRVQSVE 160 Query: 478 HL----FVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLY 606 + ++G+T+G+IG GR+G A A + + F N++++D Y Sbjct: 161 QIREVASGAARIRGETLGIIGLGRVGQAVA-LRAKAFGFNVLFYDPY 206
>CTBP1_RAT (Q9Z2F5) C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1)| (C-terminal-binding protein 3) (CtBP3) (50 kDa BFA-dependent ADP-ribosylation substrate) (BARS-50) Length = 430 Score = 50.4 bits (119), Expect = 4e-06 Identities = 30/107 (28%), Positives = 51/107 (47%), Gaps = 4/107 (3%) Frame = +1 Query: 298 GYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 477 G++N+D+ +A GIA+ N P E T RR Q +R G + Sbjct: 90 GFDNIDIKSAGDLGIAVCNVPAASVEETADSTLCHILNLYRRTTWLHQALREGTRVQSVE 149 Query: 478 HL----FVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLY 606 + ++G+T+G+IG GR+G A A + + F N++++D Y Sbjct: 150 QIREVASGAARIRGETLGIIGLGRVGQAVA-LRAKAFGFNVLFYDPY 195
>LDHD_STAAW (Q8NUT2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 49.7 bits (117), Expect = 7e-06 Identities = 35/131 (26%), Positives = 59/131 (45%) Frame = +1 Query: 214 GQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXX 393 G+L +D ++ L+ G + G++ D+D A K+ I I N P ET Sbjct: 55 GKLEDD----VYPKLESYGIKQIAQRTAGFDMYDLDLAKKHNIVISNVPSYSPETIAEYS 110 Query: 394 XXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEG 573 RR + ++ ++A +D + +K TV +IG GRIG+A A+ + G Sbjct: 111 VSIALQLVRRFPDIERRVQA--HDFTWQAEIMSKPVKNMTVAIIGTGRIGAATAK-IYAG 167 Query: 574 FKMNLIYFDLY 606 F + +D Y Sbjct: 168 FGATITAYDAY 178
>LDHD_STAAS (Q6G6F1) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 49.7 bits (117), Expect = 7e-06 Identities = 35/131 (26%), Positives = 59/131 (45%) Frame = +1 Query: 214 GQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXX 393 G+L +D ++ L+ G + G++ D+D A K+ I I N P ET Sbjct: 55 GKLEDD----VYPKLESYGIKQIAQRTAGFDMYDLDLAKKHNIVISNVPSYSPETIAEYS 110 Query: 394 XXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEG 573 RR + ++ ++A +D + +K TV +IG GRIG+A A+ + G Sbjct: 111 VSIALQLVRRFPDIERRVQA--HDFTWQAEIMSKPVKNMTVAIIGTGRIGAATAK-IYAG 167 Query: 574 FKMNLIYFDLY 606 F + +D Y Sbjct: 168 FGATITAYDAY 178
>CTBPA_XENLA (Q9YHU0) C-terminal-binding protein A (CtBP)| Length = 440 Score = 48.9 bits (115), Expect = 1e-05 Identities = 30/107 (28%), Positives = 50/107 (46%), Gaps = 4/107 (3%) Frame = +1 Query: 298 GYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 477 G++N+D+ +A GIA+ N P E T RR Q +R G + Sbjct: 101 GFDNIDIKSAGDLGIAVCNVPAASVEETADSTMCHILNLYRRTTWLHQALREGTRVQSVE 160 Query: 478 HL----FVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLY 606 + ++G+T+G+IG GR+G A A + + F N+ ++D Y Sbjct: 161 QIREVASGAARIRGETLGIIGLGRVGQAVA-LRAKTFGFNVFFYDPY 206
>LDHD_LACDE (P26297) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 332 Score = 48.9 bits (115), Expect = 1e-05 Identities = 38/143 (26%), Positives = 60/143 (41%), Gaps = 1/143 (0%) Frame = +1 Query: 181 ALIGDHCHGVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTP 360 A + GV+ D+ AL G T S VG +N+D+ A + G I N P Sbjct: 40 AALAKGADGVVVYQQLDYTAETLQALADNGITKMSLRNVGVDNIDMAKAKELGFQITNVP 99 Query: 361 GVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYD-GWLPHLFVGNLLKGQTVGVIGAGR 537 R+ D+ + +D W P +G ++ Q VGV+G G Sbjct: 100 VYSPNAIAEHAAIQAARILRQAKAMDE--KVARHDLRWAPT--IGREVRDQVVGVVGTGH 155 Query: 538 IGSAYARMMIEGFKMNLIYFDLY 606 IG + ++M EGF +I +D++ Sbjct: 156 IGQVFMQIM-EGFGAKVIAYDIF 177
>LDHD_STAAU (P72357) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 48.9 bits (115), Expect = 1e-05 Identities = 35/131 (26%), Positives = 58/131 (44%) Frame = +1 Query: 214 GQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXX 393 G+L D ++ L+ G + G++ D+D A K+ I I N P ET Sbjct: 55 GKLEND----VYPKLESYGIKQIAQRTAGFDMYDLDLAKKHNIVISNVPSYSPETIAEYS 110 Query: 394 XXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEG 573 RR + ++ ++A +D + +K TV +IG GRIG+A A+ + G Sbjct: 111 VSIALQLVRRFPDIERRVQA--HDFTWQAEIMSKPVKNMTVAIIGTGRIGAATAK-IYAG 167 Query: 574 FKMNLIYFDLY 606 F + +D Y Sbjct: 168 FGATITAYDAY 178
>LDHD_STAAR (Q6GDS2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 48.9 bits (115), Expect = 1e-05 Identities = 35/131 (26%), Positives = 58/131 (44%) Frame = +1 Query: 214 GQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXX 393 G+L D ++ L+ G + G++ D+D A K+ I I N P ET Sbjct: 55 GKLEND----VYPKLESYGIKQIAQRTAGFDMYDLDLAKKHNIVISNVPSYSPETIAEYS 110 Query: 394 XXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEG 573 RR + ++ ++A +D + +K TV +IG GRIG+A A+ + G Sbjct: 111 VSIALQLVRRFPDIERRVQA--HDFTWQAEIMSKPVKNMTVAIIGTGRIGAATAK-IYAG 167 Query: 574 FKMNLIYFDLY 606 F + +D Y Sbjct: 168 FGATITAYDAY 178
>LDHD_STAAC (Q5HD29) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 48.9 bits (115), Expect = 1e-05 Identities = 35/131 (26%), Positives = 58/131 (44%) Frame = +1 Query: 214 GQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXX 393 G+L D ++ L+ G + G++ D+D A K+ I I N P ET Sbjct: 55 GKLEND----VYPKLESYGIKQIAQRTAGFDMYDLDLAKKHNIVISNVPSYSPETIAEYS 110 Query: 394 XXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEG 573 RR + ++ ++A +D + +K TV +IG GRIG+A A+ + G Sbjct: 111 VSIALQLVRRFPDIERRVQA--HDFTWQAEIMSKPVKNMTVAIIGTGRIGAATAK-IYAG 167 Query: 574 FKMNLIYFDLY 606 F + +D Y Sbjct: 168 FGATITAYDAY 178
>LDHD_STRA3 (Q8E6A9) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 48.5 bits (114), Expect = 1e-05 Identities = 32/123 (26%), Positives = 56/123 (45%) Frame = +1 Query: 238 EVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXX 417 + ++ LK G + + G + +++ A ++GI I N P E+ Sbjct: 58 DAIYPLLKEMGIKQIAQRSAGVDMYNLELAKQHGIIISNVPSYSPESIAEFTVTIALNLI 117 Query: 418 RRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYF 597 R++ +R + LP G +L TV +IG GRIG A A+ + +GF +I + Sbjct: 118 RKVELIRANVREQNFSWTLP--IRGRVLGNMTVAIIGTGRIGLATAK-IFKGFGCRVIGY 174 Query: 598 DLY 606 D+Y Sbjct: 175 DIY 177
>LDHD_STAAN (P99116) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 48.5 bits (114), Expect = 1e-05 Identities = 35/131 (26%), Positives = 56/131 (42%) Frame = +1 Query: 214 GQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXX 393 G+L D ++ L+ G + G++ D+D A K+ I I N P ET Sbjct: 55 GKLEND----VYPKLESYGIKQIAQRTAGFDMYDLDLAKKHNIVISNVPSYSPETIAEYS 110 Query: 394 XXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEG 573 RR + ++ R +D + +K TV +IG GRIG+A A+ + G Sbjct: 111 VSIALQLVRRFPDIER--RVQTHDFTWQAEIMSKPVKNMTVAIIGTGRIGAATAK-IYAG 167 Query: 574 FKMNLIYFDLY 606 F + +D Y Sbjct: 168 FGATITAYDAY 178
>LDHD_STAAM (P63940) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 48.5 bits (114), Expect = 1e-05 Identities = 35/131 (26%), Positives = 56/131 (42%) Frame = +1 Query: 214 GQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXX 393 G+L D ++ L+ G + G++ D+D A K+ I I N P ET Sbjct: 55 GKLEND----VYPKLESYGIKQIAQRTAGFDMYDLDLAKKHNIVISNVPSYSPETIAEYS 110 Query: 394 XXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEG 573 RR + ++ R +D + +K TV +IG GRIG+A A+ + G Sbjct: 111 VSIALQLVRRFPDIER--RVQTHDFTWQAEIMSKPVKNMTVAIIGTGRIGAATAK-IYAG 167 Query: 574 FKMNLIYFDLY 606 F + +D Y Sbjct: 168 FGATITAYDAY 178
>CTBP2_MOUSE (P56546) C-terminal-binding protein 2 (CtBP2)| Length = 445 Score = 48.5 bits (114), Expect = 1e-05 Identities = 33/107 (30%), Positives = 51/107 (47%), Gaps = 4/107 (3%) Frame = +1 Query: 298 GYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 477 GY+NVD+ AA + GIA+ N P E T RR Q +R G + Sbjct: 107 GYDNVDIKAAGELGIAVCNIPSAAVEETADSTVCHILNLYRRNTWLYQALREGTRVQSVE 166 Query: 478 HL----FVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLY 606 + ++G+T+G+IG GR G A A + + F ++I++D Y Sbjct: 167 QIREVASGAARIRGETLGLIGFGRTGQAVA-VRAKAFGFSVIFYDPY 212
>CTBP2_HUMAN (P56545) C-terminal-binding protein 2 (CtBP2)| Length = 445 Score = 48.5 bits (114), Expect = 1e-05 Identities = 33/107 (30%), Positives = 51/107 (47%), Gaps = 4/107 (3%) Frame = +1 Query: 298 GYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 477 GY+NVD+ AA + GIA+ N P E T RR Q +R G + Sbjct: 107 GYDNVDIKAAGELGIAVCNIPSAAVEETADSTICHILNLYRRNTWLYQALREGTRVQSVE 166 Query: 478 HL----FVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLY 606 + ++G+T+G+IG GR G A A + + F ++I++D Y Sbjct: 167 QIREVASGAARIRGETLGLIGFGRTGQAVA-VRAKAFGFSVIFYDPY 212
>CTBP_DROME (O46036) C-terminal-binding protein (CtBP protein) (dCtBP)| Length = 476 Score = 47.8 bits (112), Expect = 3e-05 Identities = 35/114 (30%), Positives = 50/114 (43%), Gaps = 11/114 (9%) Frame = +1 Query: 298 GYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 477 G +N+DV AA + GIA+ N PG E RR +R G Sbjct: 101 GTDNIDVKAAGELGIAVCNVPGYGVEEVADTTMCLILNLYRRTYWLANMVREG------- 153 Query: 478 HLFVG-----------NLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLY 606 F G ++G T+G++G GRIGSA A + + F N+I++D Y Sbjct: 154 KKFTGPEQVREAAHGCARIRGDTLGLVGLGRIGSAVA-LRAKAFGFNVIFYDPY 206
>SERA_SYNY3 (P73821) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 554 Score = 47.4 bits (111), Expect = 3e-05 Identities = 30/102 (29%), Positives = 50/102 (49%) Frame = +1 Query: 295 VGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 474 VG +N+DV AA + GI + N+P T R I +A++ ++ W Sbjct: 100 VGVDNIDVPAATRQGIVVVNSPEGNTIAAAEHALAMMMALARHIPDANKSVKE---SKWE 156 Query: 475 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFD 600 F+G + +T+GV+G G+IGS A + + M L+ +D Sbjct: 157 RKQFIGTEVYKKTLGVVGLGKIGSHVAG-VAKAMGMKLLAYD 197
>DHD2_LACPA (P17584) D-2-hydroxyisocaproate dehydrogenase (EC 1.1.1.-)| (D-HICDH) Length = 333 Score = 47.4 bits (111), Expect = 3e-05 Identities = 35/134 (26%), Positives = 56/134 (41%) Frame = +1 Query: 205 GVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTX 384 G+ T + +F + G + VG +N+D+ A + GI + N P Sbjct: 47 GINSLQTTPYAAGVFEKMHAYGIKFLTIRNVGTDNIDMTAMKQYGIRLSNVPAYSPAAIA 106 Query: 385 XXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMM 564 R + + ++AG Y+ F+G L QTVGV+G G IG A + Sbjct: 107 EFALTDTLYLLRNMGKVQAQLQAGDYEK--AGTFIGKELGQQTVGVMGTGHIGQV-AIKL 163 Query: 565 IEGFKMNLIYFDLY 606 +GF +I +D Y Sbjct: 164 FKGFGAKVIAYDPY 177
>LDHD_LEUMC (P51011) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 331 Score = 46.2 bits (108), Expect = 7e-05 Identities = 39/127 (30%), Positives = 53/127 (41%), Gaps = 1/127 (0%) Frame = +1 Query: 229 DWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXX 408 D+ +AL G T S VG +N+D DAA + I N P Sbjct: 56 DYTRETLTALANVGVTNLSLRNVGTDNIDFDAAREFNFNISNVPVYSPNAIAEHSMLQLS 115 Query: 409 XXXRRIVEAD-QFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMN 585 RR D + + L W P G ++ QTVGVIG G IG A +++GF Sbjct: 116 RLLRRTKALDAKIAKRDL--RWAP--TTGREMRMQTVGVIGTGHIGRV-AINILKGFGAK 170 Query: 586 LIYFDLY 606 +I +D Y Sbjct: 171 VIAYDKY 177
>LDHD_STAES (Q8CN22) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 46.2 bits (108), Expect = 7e-05 Identities = 38/158 (24%), Positives = 67/158 (42%), Gaps = 3/158 (1%) Frame = +1 Query: 142 TEKKTILSVDDILALIGDHCHGVIGQLTEDWGEV---LFSALKRAGGTAFSNMAVGYNNV 312 T +LSVD + D G T +G++ ++ L+ G + G++ Sbjct: 29 TTSTELLSVDTV-----DQLKDYDGVTTMQFGKLEPEVYPKLESYGIKQIAQRTAGFDMY 83 Query: 313 DVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVG 492 D++ A K+ I I N P ET R+ ++ ++A + P + Sbjct: 84 DLELAKKHEIIISNIPSYSPETIAEYSVSIALQLVRKFPTIEKRVQAHNFTWASP--IMS 141 Query: 493 NLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLY 606 +K TV +IG GRIG+A + + GF ++ +D Y Sbjct: 142 RPVKNMTVAIIGTGRIGAATGK-IYAGFGARVVGYDAY 178
>LDHD_STAEQ (Q5HLA0) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 46.2 bits (108), Expect = 7e-05 Identities = 38/158 (24%), Positives = 67/158 (42%), Gaps = 3/158 (1%) Frame = +1 Query: 142 TEKKTILSVDDILALIGDHCHGVIGQLTEDWGEV---LFSALKRAGGTAFSNMAVGYNNV 312 T +LSVD + D G T +G++ ++ L+ G + G++ Sbjct: 29 TTSTELLSVDTV-----DQLKDYDGVTTMQFGKLEPEVYPKLESYGIKQIAQRTAGFDMY 83 Query: 313 DVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVG 492 D++ A K+ I I N P ET R+ ++ ++A + P + Sbjct: 84 DLELAKKHEIIISNIPSYSPETIAEYSVSIALQLVRKFPTIEKRVQAHNFTWASP--IMS 141 Query: 493 NLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLY 606 +K TV +IG GRIG+A + + GF ++ +D Y Sbjct: 142 RPVKNMTVAIIGTGRIGAATGK-IYAGFGARVVGYDAY 178
>SERA_SCHPO (P87228) Putative D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95)| (3-PGDH) Length = 466 Score = 44.7 bits (104), Expect = 2e-04 Identities = 38/154 (24%), Positives = 72/154 (46%), Gaps = 3/154 (1%) Frame = +1 Query: 151 KTILSVDDILALI-GDHCHGVIGQ--LTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVD 321 KT +S DD++ I G H G+ + LT E S + +G N VD+D Sbjct: 83 KTSMSEDDLVEKIKGVHAIGIRSKTRLTRRVLEAADSLI------VIGCFCIGTNQVDLD 136 Query: 322 AANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLL 501 A + GIA+ N+P + + R++ + + G ++ + + Sbjct: 137 FAAERGIAVFNSPYANSRSVAELVIGYIISLARQVGDRSLELHRGEWNKVSSGCWE---I 193 Query: 502 KGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDL 603 +G+T+G+IG G IGS + ++ E ++++Y+D+ Sbjct: 194 RGKTLGIIGYGHIGSQLS-VLAEAMGLHVVYYDI 226
>VANH_ENTFA (Q47748) D-specific alpha-keto acid dehydrogenase (EC 1.1.1.-)| (Vancomycin B-type resistance protein vanHB) Length = 323 Score = 44.7 bits (104), Expect = 2e-04 Identities = 38/147 (25%), Positives = 61/147 (41%) Frame = +1 Query: 160 LSVDDILALIGDHCHGVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNG 339 +S D+ G+ C V G +E E AL++ G S ++G N++D AA + G Sbjct: 38 ISADNAKLAAGNQCISV-GHKSEV-SEATILALRKVGVKYISTRSIGCNHIDTTAAERMG 95 Query: 340 IAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVG 519 I++G + + I A + A + G L+ TVG Sbjct: 96 ISVGT----VAYSPDSVADYALMLMLMAIRGAKSTIHAVAQQNFRLDCVRGKELRDMTVG 151 Query: 520 VIGAGRIGSAYARMMIEGFKMNLIYFD 600 VIG G IG A + + GF ++ +D Sbjct: 152 VIGTGHIGQAVVK-RLRGFGCRVLAYD 177
>SERA_YEAST (P40054) D-3-phosphoglycerate dehydrogenase 1 (EC 1.1.1.95) (3-PGDH| 1) Length = 469 Score = 43.9 bits (102), Expect = 4e-04 Identities = 25/103 (24%), Positives = 52/103 (50%) Frame = +1 Query: 295 VGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 474 +G N VD+D A GIA+ N+P + + R++ + + G ++ Sbjct: 131 IGTNQVDLDYATSRGIAVFNSPFSNSRSVAELVIAEIISLARQLGDRSIELHTGTWNKVA 190 Query: 475 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDL 603 + ++G+T+G+IG G IGS + ++ E ++++Y+D+ Sbjct: 191 ARCWE---VRGKTLGIIGYGHIGSQLS-VLAEAMGLHVLYYDI 229
>LDHD_STRP1 (Q99ZM2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 43.5 bits (101), Expect = 5e-04 Identities = 30/123 (24%), Positives = 54/123 (43%) Frame = +1 Query: 238 EVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXX 417 + ++ LK G + + + ++D A +N I I N P E+ Sbjct: 58 DAIYPLLKEMGIKQIAQHSASVDMYNLDLATENDIIITNVPSYSPESIAEFTVTIVLNLI 117 Query: 418 RRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYF 597 R + + ++ + LP G +L TV +IG GRIG A A+ + +GF ++ + Sbjct: 118 RHVELIRENVKKQNFTWGLP--IRGRVLGDMTVAIIGTGRIGLATAK-IFKGFGCKVVGY 174 Query: 598 DLY 606 D+Y Sbjct: 175 DIY 177
>SERA_SHIFL (P0A9T3) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 409 Score = 43.1 bits (100), Expect = 6e-04 Identities = 30/110 (27%), Positives = 51/110 (46%), Gaps = 1/110 (0%) Frame = +1 Query: 277 AFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAG 456 A +G N VD+DAA K GI + N P T + R + EA+ G Sbjct: 77 AIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRG 136 Query: 457 LYDGWLPHLFVGNL-LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDL 603 +++ L G+ +G+ +G+IG G IG+ ++ E M + ++D+ Sbjct: 137 VWN----KLAAGSFEARGKKLGIIGYGHIGTQLG-ILAESLGMYVYFYDI 181
>SERA_ECOLI (P0A9T0) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 409 Score = 43.1 bits (100), Expect = 6e-04 Identities = 30/110 (27%), Positives = 51/110 (46%), Gaps = 1/110 (0%) Frame = +1 Query: 277 AFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAG 456 A +G N VD+DAA K GI + N P T + R + EA+ G Sbjct: 77 AIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRG 136 Query: 457 LYDGWLPHLFVGNL-LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDL 603 +++ L G+ +G+ +G+IG G IG+ ++ E M + ++D+ Sbjct: 137 VWN----KLAAGSFEARGKKLGIIGYGHIGTQLG-ILAESLGMYVYFYDI 181
>SERA_ECOL6 (P0A9T1) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 409 Score = 43.1 bits (100), Expect = 6e-04 Identities = 30/110 (27%), Positives = 51/110 (46%), Gaps = 1/110 (0%) Frame = +1 Query: 277 AFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAG 456 A +G N VD+DAA K GI + N P T + R + EA+ G Sbjct: 77 AIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRG 136 Query: 457 LYDGWLPHLFVGNL-LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDL 603 +++ L G+ +G+ +G+IG G IG+ ++ E M + ++D+ Sbjct: 137 VWN----KLAAGSFEARGKKLGIIGYGHIGTQLG-ILAESLGMYVYFYDI 181
>SERA_ECO57 (P0A9T2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 409 Score = 43.1 bits (100), Expect = 6e-04 Identities = 30/110 (27%), Positives = 51/110 (46%), Gaps = 1/110 (0%) Frame = +1 Query: 277 AFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAG 456 A +G N VD+DAA K GI + N P T + R + EA+ G Sbjct: 77 AIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRG 136 Query: 457 LYDGWLPHLFVGNL-LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDL 603 +++ L G+ +G+ +G+IG G IG+ ++ E M + ++D+ Sbjct: 137 VWN----KLAAGSFEARGKKLGIIGYGHIGTQLG-ILAESLGMYVYFYDI 181
>SERA_HAEIN (P43885) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 410 Score = 42.7 bits (99), Expect = 8e-04 Identities = 26/103 (25%), Positives = 50/103 (48%) Frame = +1 Query: 295 VGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 474 +G N VD++AA GI + N P T + R + +A+ + G+ W Sbjct: 85 IGTNQVDLNAAKARGIPVFNAPFSNTRSVAELVLGEILLLMRNVPQANAEVHRGV---WN 141 Query: 475 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDL 603 + ++G+ +G+IG G IGS + ++ E M++ ++D+ Sbjct: 142 KSATGSHEVRGKKLGIIGYGHIGSQLS-IIAESLGMDVYFYDI 183
>SER33_YEAST (P40510) D-3-phosphoglycerate dehydrogenase 2 (EC 1.1.1.95) (3-PGDH| 2) Length = 469 Score = 40.4 bits (93), Expect = 0.004 Identities = 40/172 (23%), Positives = 77/172 (44%), Gaps = 4/172 (2%) Frame = +1 Query: 100 IKLLTDNDCRLEICTEKKTILSVDDILALIGD-HCHGVIGQ--LTEDWGEVLFSALKRAG 270 IK+ D ++E K+ L D+++ I D H G+ + LTE L+ A Sbjct: 72 IKIFKDQGYQVEF---HKSSLPEDELIEKIKDVHAIGIRSKTRLTE-------KILQHAR 121 Query: 271 G-TAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFM 447 +G N VD+ A GIA+ N+P + + R++ + + Sbjct: 122 NLVCIGCFCIGTNQVDLKYAASKGIAVFNSPFSNSRSVAELVIGEIISLARQLGDRSIEL 181 Query: 448 RAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDL 603 G ++ + ++G+T+G+IG G IGS + ++ E ++++Y+D+ Sbjct: 182 HTGTWNKVAARCWE---VRGKTLGIIGYGHIGSQLS-VLAEAMGLHVLYYDI 229
>VANH_ENTFC (Q05709) D-specific alpha-keto acid dehydrogenase (EC 1.1.1.-)| (Vancomycin resistance protein vanH) Length = 322 Score = 40.0 bits (92), Expect = 0.005 Identities = 35/118 (29%), Positives = 50/118 (42%), Gaps = 5/118 (4%) Frame = +1 Query: 211 IGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGN---TPGVLTETT 381 +G +E +L ALKRAG S ++G N++D AA + GI + N +P + + T Sbjct: 53 VGHKSEISASILL-ALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAYSPDSVADYT 111 Query: 382 XXXXXXXXXXXXR--RIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSA 549 R VE F G +L TVGV+G G+IG A Sbjct: 112 MMLILMAVRNVKSIVRSVEKHDFRLDS---------DRGKVLSDMTVGVVGTGQIGKA 160
>LDHD_LACPE (P26298) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 332 Score = 40.0 bits (92), Expect = 0.005 Identities = 34/127 (26%), Positives = 52/127 (40%) Frame = +1 Query: 226 EDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXX 405 +D+ + + L G S VG +N+DV G+ I N P Sbjct: 55 KDYTAEVLNKLADEGVKNISLRNVGVDNLDVPTVKARGLNISNVPAYSPNAIAELSVTQL 114 Query: 406 XXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMN 585 R+ ++ + + W P + L TVGVIG GRIG A A + +GF Sbjct: 115 MQLLRQTPMFNKKLAKQDFR-WAPD--IAKELNTMTVGVIGTGRIGRA-AIDIFKGFGAK 170 Query: 586 LIYFDLY 606 +I +D+Y Sbjct: 171 VIGYDVY 177
>LDHD_LACPL (Q88VJ2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH)| Length = 332 Score = 39.7 bits (91), Expect = 0.007 Identities = 34/127 (26%), Positives = 52/127 (40%) Frame = +1 Query: 226 EDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXX 405 +D+ + + L G S VG +N+DV G+ I N P Sbjct: 55 KDYTAEVLNKLADEGVKNISLRNVGVDNLDVPTVKARGLNISNVPAYSPNAIAELSVTQL 114 Query: 406 XXXXRRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMN 585 R+ ++ + + W P + L TVGVIG GRIG A A + +GF Sbjct: 115 MQLLRQTPLFNKKLAKQDFR-WAPD--IAKELNTMTVGVIGTGRIGRA-AIDIFKGFGAK 170 Query: 586 LIYFDLY 606 +I +D+Y Sbjct: 171 VIGYDVY 177
>LDHD_TREPA (O83080) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 331 Score = 38.1 bits (87), Expect = 0.020 Identities = 28/108 (25%), Positives = 43/108 (39%) Frame = +1 Query: 283 SNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLY 462 S G++ + K+GI + N P R E + F+R + Sbjct: 74 STRTAGFDMYNATLLKKHGIRLTNVPSYSPNAIGEYALAAALQLTRHAREIETFVRKRDF 133 Query: 463 DGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLY 606 P L L+ VG++G GRIG A AR + +G ++ FD Y Sbjct: 134 RWQKPIL--SKELRCSRVGILGTGRIGQAAAR-LFKGVGAQVVGFDPY 178
>FDH_NEUCR (Q07103) Formate dehydrogenase (EC 1.2.1.2) (NAD-dependent formate| dehydrogenase) (FDH) Length = 375 Score = 37.4 bits (85), Expect = 0.034 Identities = 28/105 (26%), Positives = 46/105 (43%), Gaps = 3/105 (2%) Frame = +1 Query: 295 VGYNNVDVDAANKN--GIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDG 468 +G ++VD++AANK GI + G + R V A + ++ G +D Sbjct: 94 IGSDHVDLNAANKTNGGITVAEVTGSNVVSVAEHVLMTILVLVRNFVPAHEQIQEGRWD- 152 Query: 469 WLPHLFVGNL-LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFD 600 + L+G+ VG +G GRIG R + L+Y+D Sbjct: 153 -VAEAAKNEFDLEGKVVGTVGVGRIGERVLRRLKPFDCKELLYYD 196
>FDH_EMENI (Q03134) Probable formate dehydrogenase (EC 1.2.1.2) (NAD-dependent| formate dehydrogenase) (FDH) Length = 377 Score = 37.0 bits (84), Expect = 0.044 Identities = 30/106 (28%), Positives = 43/106 (40%), Gaps = 4/106 (3%) Frame = +1 Query: 295 VGYNNVDVDAANKN--GIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDG 468 +G ++VD+DAANK GI + G + R V A +R G Sbjct: 89 IGSDHVDLDAANKTNGGITVAEVTGSNVVSVAEHVVMTILLLVRNFVPAHDQIRNG---D 145 Query: 469 WLPHLFVGNL--LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFD 600 W N L+ + VG +G GRIG R + L+Y+D Sbjct: 146 WNVAAVAKNEFDLENKVVGTVGVGRIGERVLRRLKPFDCKELLYYD 191
>YEAA_SCHPO (O14075) Putative 2-hydroxyacid dehydrogenase UNK4.10 (EC 1.-.-.-)| Length = 334 Score = 35.8 bits (81), Expect = 0.099 Identities = 24/107 (22%), Positives = 43/107 (40%), Gaps = 4/107 (3%) Frame = +1 Query: 286 NMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYD 465 ++ GY VDV A GI + + P + + T R G+++ Sbjct: 86 HLGAGYETVDVAACTARGIQVSHVPKAVDDATADVGIFLMLGALRG-------FNQGIFE 138 Query: 466 ----GWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIY 594 W + + +G+T+G++G G IG A+ F M ++Y Sbjct: 139 LHKNNWNANCKPSHDPEGKTLGILGLGGIGKTMAK-RARAFDMKIVY 184
>YN14_YEAST (P53839) Putative 2-hydroxyacid dehydrogenase YNL274C (EC 1.-.-.-)| Length = 350 Score = 35.4 bits (80), Expect = 0.13 Identities = 29/109 (26%), Positives = 47/109 (43%), Gaps = 3/109 (2%) Frame = +1 Query: 277 AFSNMAVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAG 456 A + GY+ +DV+ K I + N P +++ T R ++ + G Sbjct: 85 AVCHTGAGYDQIDVEPFKKRHIQVANVPDLVSNATADTHVFLLLGALRNFGIGNRRLIEG 144 Query: 457 LYDGWLPHLF--VGNLLKGQTVGVIGAGRIGSA-YARMMIEGFKMNLIY 594 + P G +G+TVG++G GRIG R+ GF+ N IY Sbjct: 145 NWPEAGPACGSPFGYDPEGKTVGILGLGRIGRCILERLKPFGFE-NFIY 192
>FDH_SOLTU (Q07511) Formate dehydrogenase, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase) (FDH) Length = 381 Score = 35.0 bits (79), Expect = 0.17 Identities = 27/103 (26%), Positives = 46/103 (44%), Gaps = 1/103 (0%) Frame = +1 Query: 295 VGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYD-GW 471 +G ++VD+ AA G+ + G T + R + + G ++ Sbjct: 125 IGSDHVDLKAAAAAGLTVAEVTGSNTVSVAEDELMRILILVRNFLPGHHQVINGEWNVAA 184 Query: 472 LPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFD 600 + H L+G+TVG +GAGRIG + ++ F NL+Y D Sbjct: 185 IAHRAYD--LEGKTVGTVGAGRIGRLLLQ-RLKPFNCNLLYHD 224
>FDH2_ORYSA (Q67U69) Formate dehydrogenase 2, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase 2) (FDH 2) Length = 378 Score = 34.7 bits (78), Expect = 0.22 Identities = 27/103 (26%), Positives = 46/103 (44%), Gaps = 1/103 (0%) Frame = +1 Query: 295 VGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYD-GW 471 VG +++D+ AA G+ + G T + R + + G ++ Sbjct: 122 VGSDHIDLPAAAAAGLTVAEITGSNTVSVAEDQLMRILLLLRNFLPGHHQIVNGEWNVAG 181 Query: 472 LPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFD 600 + H L+G+TVG +GAGRIG + ++ F NL+Y D Sbjct: 182 IAHRTYD--LEGKTVGTVGAGRIGRLLLQ-RLKPFNCNLMYHD 221
>FDH1_ORYSA (Q9SXP2) Formate dehydrogenase 1, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase 1) (FDH 1) Length = 376 Score = 34.7 bits (78), Expect = 0.22 Identities = 26/102 (25%), Positives = 46/102 (45%) Frame = +1 Query: 295 VGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 474 +G +++D+ AA G+ + G T + R + Q + G ++ Sbjct: 120 IGSDHIDLPAAAAAGLTVAEVTGSNTVSVAEDELMRILILLRNFLPGYQQVVHGEWNV-A 178 Query: 475 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFD 600 + L+G+TVG +GAGRIG + ++ F NL+Y D Sbjct: 179 GIAYRAYDLEGKTVGTVGAGRIGRLLLQ-RLKPFNCNLLYHD 219
>FDH_HORVU (Q9ZRI8) Formate dehydrogenase, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase) (FDH) Length = 377 Score = 34.7 bits (78), Expect = 0.22 Identities = 26/103 (25%), Positives = 46/103 (44%), Gaps = 1/103 (0%) Frame = +1 Query: 295 VGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYD-GW 471 +G +++D+ AA G+ + G T + R + Q + G ++ Sbjct: 121 IGSDHIDLPAAAAAGLTVARVTGSNTVSVAEDELMRILILLRNFLPGYQQVVKGEWNVAG 180 Query: 472 LPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFD 600 + H L+G+TVG +GAGR G + ++ F NL+Y D Sbjct: 181 IAHRAYD--LEGKTVGTVGAGRYGRLLLQ-RLKPFNCNLLYHD 220
>FDH_ARATH (Q9S7E4) Formate dehydrogenase, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase) (FDH) Length = 384 Score = 32.7 bits (73), Expect = 0.84 Identities = 15/34 (44%), Positives = 23/34 (67%) Frame = +1 Query: 499 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFD 600 L+G+T+G +GAGRIG + ++ F NL+Y D Sbjct: 195 LEGKTIGTVGAGRIGKLLLQ-RLKPFGCNLLYHD 227
>HSP1_SAISC (Q9GKQ1) Sperm protamine P1| Length = 49 Score = 31.6 bits (70), Expect = 1.9 Identities = 17/37 (45%), Positives = 20/37 (54%) Frame = -3 Query: 355 CCRWRCRSCWQHRRQRCCTRQPYC*RLSHQRA*GQRR 245 CCR R RS RR+RC TR+ C R R +RR Sbjct: 5 CCRSRSRSRCYRRRRRCRTRRRRCCRRRRARRCCRRR 41
>Y1598_METJA (Q58993) UPF0284 protein MJ1598| Length = 350 Score = 31.2 bits (69), Expect = 2.4 Identities = 23/71 (32%), Positives = 33/71 (46%) Frame = +1 Query: 163 SVDDILALIGDHCHGVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNVDVDAANKNGI 342 SV D+L +GD V+ L + E + AGGT S + ++ +KN I Sbjct: 204 SVFDVLNAVGDKMMPVVAGLAISFAERNKPVIL-AGGTQMSAVLAVIKEINKKVLDKNLI 262 Query: 343 AIGNTPGVLTE 375 AIG T VL + Sbjct: 263 AIGTTEFVLND 273
>FDH_PICAN (P33677) Formate dehydrogenase (EC 1.2.1.2) (NAD-dependent formate| dehydrogenase) (FDH) Length = 361 Score = 31.2 bits (69), Expect = 2.4 Identities = 25/106 (23%), Positives = 46/106 (43%), Gaps = 4/106 (3%) Frame = +1 Query: 295 VGYNNVDVDAANKNG--IAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDG 468 VG +++D+D N++G I++ G + R V A + + +G G Sbjct: 92 VGSDHIDLDYINQSGRDISVLEVTGSNVVSVAEHVVMTMLVLVRNFVPAHEQIISG---G 148 Query: 469 WLPHLFVGNL--LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFD 600 W + ++G+ + IGAGRIG ++ L+Y+D Sbjct: 149 WNVAEIAKDSFDIEGKVIATIGAGRIGYRVLERLVAFNPKELLYYD 194
>HSP1_RAT (P10118) Sperm protamine P1 (Cysteine-rich protamine)| Length = 50 Score = 30.8 bits (68), Expect = 3.2 Identities = 15/38 (39%), Positives = 22/38 (57%) Frame = -3 Query: 355 CCRWRCRSCWQHRRQRCCTRQPYC*RLSHQRA*GQRRA 242 CCR + RS + RR+RC R+ C R +R +RR+ Sbjct: 5 CCRSKSRSRCRRRRRRCRRRRRRCCRRRRRRCCRRRRS 42
>HSP1_PAPCY (Q7JIX8) Sperm protamine P1| Length = 50 Score = 30.8 bits (68), Expect = 3.2 Identities = 15/37 (40%), Positives = 20/37 (54%) Frame = -3 Query: 349 RWRCRSCWQHRRQRCCTRQPYC*RLSHQRA*GQRRAL 239 R+RC C R RCC R+ C R +R +RRA+ Sbjct: 2 RYRC--CRSQSRSRCCRRRRRCRRRRRRRCRARRRAM 36
>HSP1_MOUSE (P02319) Sperm protamine P1 (Cysteine-rich protamine)| Length = 50 Score = 30.8 bits (68), Expect = 3.2 Identities = 15/38 (39%), Positives = 22/38 (57%) Frame = -3 Query: 355 CCRWRCRSCWQHRRQRCCTRQPYC*RLSHQRA*GQRRA 242 CCR + RS + RR+RC R+ C R +R +RR+ Sbjct: 5 CCRSKSRSRCRRRRRRCRRRRRRCCRRRRRRCCRRRRS 42
>HSP1_MACMU (Q9GJU4) Sperm protamine P1| Length = 50 Score = 30.8 bits (68), Expect = 3.2 Identities = 15/37 (40%), Positives = 20/37 (54%) Frame = -3 Query: 349 RWRCRSCWQHRRQRCCTRQPYC*RLSHQRA*GQRRAL 239 R+RC C R RCC R+ C R +R +RRA+ Sbjct: 2 RYRC--CRSQSRSRCCRRRRRCRRRRRRRCRARRRAM 36
>DHGY_METEX (Q59516) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-dependent| hydroxypyruvate reductase) (HPR) (GDH) (Hydroxypyruvate dehydrogenase) (Glyoxylate reductase) (HPR-A) Length = 313 Score = 30.8 bits (68), Expect = 3.2 Identities = 27/108 (25%), Positives = 43/108 (39%), Gaps = 3/108 (2%) Frame = +1 Query: 292 AVGYNNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGW 471 A G + VD AA GI + N T R IV +R G ++ Sbjct: 72 ATGTDVVDKAAAKAQGITVVNIRNYAFNTVPEHVVGLMFALRRAIVPYANSVRRGDWNKS 131 Query: 472 LPHLFVGNLL---KGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLY 606 + + G T+G+IG G +G + A+ E M ++ FD++ Sbjct: 132 KQFCYFDYPIYDIAGSTLGIIGYGALGKSIAK-RAEALGMKVLAFDVF 178
>HSP1_NATMI (Q8WNZ4) Sperm protamine P1| Length = 49 Score = 30.4 bits (67), Expect = 4.2 Identities = 14/31 (45%), Positives = 19/31 (61%) Frame = -3 Query: 355 CCRWRCRSCWQHRRQRCCTRQPYC*RLSHQR 263 CCR + RS + RR+RC TR+ C R +R Sbjct: 5 CCRSQSRSRCRRRRRRCRTRRRRCCRRRRRR 35
>LGUL_VIBPA (P46235) Probable lactoylglutathione lyase (EC 4.4.1.5)| (Methylglyoxalase) (Aldoketomutase) (Glyoxalase I) (Glx I) (Ketone-aldehyde mutase) (S-D-lactoylglutathione methylglyoxal lyase) Length = 138 Score = 30.4 bits (67), Expect = 4.2 Identities = 13/41 (31%), Positives = 24/41 (58%) Frame = +1 Query: 190 GDHCHGVIGQLTEDWGEVLFSALKRAGGTAFSNMAVGYNNV 312 GD G + +LT +WG+ + GTAF ++A+G +++ Sbjct: 50 GDESQGAVIELTYNWGKTEYDL-----GTAFGHIAIGVDDI 85
>HSP1_COLBA (Q8MJT0) Sperm protamine P1| Length = 50 Score = 30.0 bits (66), Expect = 5.4 Identities = 15/37 (40%), Positives = 19/37 (51%) Frame = -3 Query: 349 RWRCRSCWQHRRQRCCTRQPYC*RLSHQRA*GQRRAL 239 R+RC C R RCC R+ C R QR +R A+ Sbjct: 2 RYRC--CRSQSRSRCCRRRRRCRRRRRQRCRARRTAM 36
>LX12B_HUMAN (O75342) Arachidonate 12-lipoxygenase, 12R type (EC 1.13.11.-)| (Epidermis-type lipoxygenase 12) (12R-lipoxygenase) (12R-LOX) Length = 701 Score = 30.0 bits (66), Expect = 5.4 Identities = 13/30 (43%), Positives = 17/30 (56%) Frame = -1 Query: 312 NVVVPDSHIAEGCPTSALEGREEHFPPVLC 223 N+ + D I EG PT L GR++H LC Sbjct: 312 NIYLADYRIMEGIPTVELSGRKQHHCAPLC 341
>PDXB_SHEON (Q8ECR2) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 376 Score = 30.0 bits (66), Expect = 5.4 Identities = 14/34 (41%), Positives = 23/34 (67%) Frame = +1 Query: 499 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFD 600 L+G+ VG++GAG GSA A+ +E F + ++ D Sbjct: 115 LRGKVVGIVGAGNTGSATAK-CLEAFGIKVLLND 147
>HSP1_NATST (Q8WNZ3) Sperm protamine P1| Length = 49 Score = 29.6 bits (65), Expect = 7.1 Identities = 14/31 (45%), Positives = 19/31 (61%) Frame = -3 Query: 355 CCRWRCRSCWQHRRQRCCTRQPYC*RLSHQR 263 CCR + RS + RR+RC TR+ C R +R Sbjct: 5 CCRSQSRSRCRPRRRRCRTRRRRCCRRRRRR 35
>YGY3_HALSQ (P21561) Hypothetical 50.6 kDa protein in the 5'region of gyrA and| gyrB (ORF 3) Length = 437 Score = 29.6 bits (65), Expect = 7.1 Identities = 23/65 (35%), Positives = 27/65 (41%) Frame = +3 Query: 36 GVEPKRQVPRGEHQVHAWHPLDQAPH*QRLPP*DMHGEEDHPLRRRHPGSHRRSLPRCHR 215 G P+RQ R E HA P + P P R R G+HRR L + R Sbjct: 151 GAHPRRQRLR-EQPRHAGRPRRRQP----------------PRRGRSRGTHRRHLRQAPR 193 Query: 216 PANRG 230 PA RG Sbjct: 194 PAVRG 198
>GPH_RHILO (Q98ML8) Phosphoglycolate phosphatase (EC 3.1.3.18) (PGPase) (PGP)| Length = 227 Score = 29.6 bits (65), Expect = 7.1 Identities = 25/78 (32%), Positives = 36/78 (46%), Gaps = 5/78 (6%) Frame = +1 Query: 130 LEICTEKKTILSVDDILAL-IGDHCHGVIGQLTEDWGEV----LFSALKRAGGTAFSNMA 294 L ICT K S+ I AL + H + GQ T + + L ++ AGG A + Sbjct: 109 LAICTNKYEANSLALIEALGLTRHFAAIAGQDTFAFRKPDPRHLTETIRLAGGDAHRALM 168 Query: 295 VGYNNVDVDAANKNGIAI 348 VG + D+D A GI + Sbjct: 169 VGDSQTDIDTAKAAGIPV 186
>CO6A2_MOUSE (Q02788) Collagen alpha-2(VI) chain precursor| Length = 1029 Score = 29.6 bits (65), Expect = 7.1 Identities = 15/40 (37%), Positives = 22/40 (55%) Frame = +1 Query: 31 IEVWNPSGKYRVVSTKSMPGTRWIKLLTDNDCRLEICTEK 150 +EV++P G R TKS+ G R + T DC L T++ Sbjct: 115 VEVFSPPGSDRASFTKSLQGIRSFRRGTFTDCALANMTQQ 154
>PDXB_VIBVU (Q8DB36) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 377 Score = 29.6 bits (65), Expect = 7.1 Identities = 13/31 (41%), Positives = 22/31 (70%) Frame = +1 Query: 508 QTVGVIGAGRIGSAYARMMIEGFKMNLIYFD 600 QTVG+IGAG++GS Y + ++G + ++ D Sbjct: 118 QTVGIIGAGQVGS-YLQQCLQGIGIKVLIND 147
>PDXB_SHEVI (Q56733) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| (Fragment) Length = 274 Score = 29.6 bits (65), Expect = 7.1 Identities = 12/22 (54%), Positives = 17/22 (77%) Frame = +1 Query: 499 LKGQTVGVIGAGRIGSAYARMM 564 LK +TVG++GAG GSA A+ + Sbjct: 2 LKDKTVGIVGAGNTGSAVAKCL 23
>PDXB_SHESP (Q56731) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| (Fragment) Length = 274 Score = 29.6 bits (65), Expect = 7.1 Identities = 12/22 (54%), Positives = 17/22 (77%) Frame = +1 Query: 499 LKGQTVGVIGAGRIGSAYARMM 564 LK +TVG++GAG GSA A+ + Sbjct: 2 LKDKTVGIVGAGNTGSAVAKCL 23
>MDH_GLOVI (Q7NHJ3) Malate dehydrogenase (EC 1.1.1.37)| Length = 325 Score = 29.6 bits (65), Expect = 7.1 Identities = 11/30 (36%), Positives = 21/30 (70%) Frame = +1 Query: 514 VGVIGAGRIGSAYARMMIEGFKMNLIYFDL 603 V ++GAG +GSA A+ +I+G +++ D+ Sbjct: 11 VSILGAGNVGSALAQRLIQGNVADVVLLDI 40
>PDXB_VIBVY (Q7MIT6) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 377 Score = 29.3 bits (64), Expect = 9.3 Identities = 12/31 (38%), Positives = 22/31 (70%) Frame = +1 Query: 508 QTVGVIGAGRIGSAYARMMIEGFKMNLIYFD 600 QTVG++GAG++GS Y + ++G + ++ D Sbjct: 118 QTVGIVGAGQVGS-YLQQCLQGIGIKVLIND 147
>PDXB_VIBPA (Q87MN8) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 377 Score = 29.3 bits (64), Expect = 9.3 Identities = 13/31 (41%), Positives = 22/31 (70%) Frame = +1 Query: 508 QTVGVIGAGRIGSAYARMMIEGFKMNLIYFD 600 +TVG+IGAG++GS Y ++G +N++ D Sbjct: 118 KTVGIIGAGQVGS-YLEKCLKGMGINVLIND 147
>GID_STAAW (P64236) tRNA uridine 5-carboxymethylaminomethyl modification| enzyme gid Length = 435 Score = 29.3 bits (64), Expect = 9.3 Identities = 17/29 (58%), Positives = 19/29 (65%), Gaps = 1/29 (3%) Frame = +1 Query: 508 QTVGVIGAGRIGSAYARMMIE-GFKMNLI 591 QTV VIGAG GS A + E G K+NLI Sbjct: 3 QTVNVIGAGLAGSEAAYQLAERGIKVNLI 31
>GID_STAAS (Q6G9W2) tRNA uridine 5-carboxymethylaminomethyl modification| enzyme gid Length = 435 Score = 29.3 bits (64), Expect = 9.3 Identities = 17/29 (58%), Positives = 19/29 (65%), Gaps = 1/29 (3%) Frame = +1 Query: 508 QTVGVIGAGRIGSAYARMMIE-GFKMNLI 591 QTV VIGAG GS A + E G K+NLI Sbjct: 3 QTVNVIGAGLAGSEAAYQLAERGIKVNLI 31
>GID_STAAN (P64235) tRNA uridine 5-carboxymethylaminomethyl modification| enzyme gid Length = 435 Score = 29.3 bits (64), Expect = 9.3 Identities = 17/29 (58%), Positives = 19/29 (65%), Gaps = 1/29 (3%) Frame = +1 Query: 508 QTVGVIGAGRIGSAYARMMIE-GFKMNLI 591 QTV VIGAG GS A + E G K+NLI Sbjct: 3 QTVNVIGAGLAGSEAAYQLAERGIKVNLI 31
>GID_STAAM (P64234) tRNA uridine 5-carboxymethylaminomethyl modification| enzyme gid Length = 435 Score = 29.3 bits (64), Expect = 9.3 Identities = 17/29 (58%), Positives = 19/29 (65%), Gaps = 1/29 (3%) Frame = +1 Query: 508 QTVGVIGAGRIGSAYARMMIE-GFKMNLI 591 QTV VIGAG GS A + E G K+NLI Sbjct: 3 QTVNVIGAGLAGSEAAYQLAERGIKVNLI 31
>GID_STAAC (Q5HGI1) tRNA uridine 5-carboxymethylaminomethyl modification| enzyme gid Length = 435 Score = 29.3 bits (64), Expect = 9.3 Identities = 17/29 (58%), Positives = 19/29 (65%), Gaps = 1/29 (3%) Frame = +1 Query: 508 QTVGVIGAGRIGSAYARMMIE-GFKMNLI 591 QTV VIGAG GS A + E G K+NLI Sbjct: 3 QTVNVIGAGLAGSEAAYQLAERGIKVNLI 31
>CHEB2_RALEJ (Q46PH7) Chemotaxis response regulator protein-glutamate| methylesterase 2 (EC 3.1.1.61) Length = 356 Score = 29.3 bits (64), Expect = 9.3 Identities = 20/78 (25%), Positives = 36/78 (46%) Frame = -2 Query: 266 ARLRAEKSTSPQSSVSWPMTPWQ*SPMRARMSSTERMVFFSVHISRRQSLSVRSLIQRVP 87 A RA +PQ++ P TP +R+ + STE+++ +++ L+ P Sbjct: 131 AASRARVRQAPQAASGTPATPM----LRSPLLSTEKLIILGASTGGTEAIK-DFLMPLPP 185 Query: 86 GMDLVLTTRYLPLGFHTS 33 VL +++P GF S Sbjct: 186 DSPAVLIVQHMPAGFTRS 203
>MYSA_DROME (P05661) Myosin heavy chain, muscle| Length = 1962 Score = 29.3 bits (64), Expect = 9.3 Identities = 24/79 (30%), Positives = 42/79 (53%), Gaps = 4/79 (5%) Frame = +1 Query: 58 YRVVSTKSMPGTRWIKLLTDNDCRLEICTE-KKTILSVDDILAL-IGDHCHGVIGQLTED 231 Y+++S S+PG + I LLTDN I ++ K T+ S+DD + D ++G ++ Sbjct: 286 YQIMSG-SVPGVKDICLLTDNIYDYHIVSQGKVTVASIDDAEEFSLTDQAFDILGFTKQE 344 Query: 232 WGEV--LFSALKRAGGTAF 282 +V + +A+ GG F Sbjct: 345 KEDVYRITAAVMHMGGMKF 363 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 82,423,689 Number of Sequences: 219361 Number of extensions: 1661410 Number of successful extensions: 6027 Number of sequences better than 10.0: 111 Number of HSP's better than 10.0 without gapping: 5703 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5961 length of database: 80,573,946 effective HSP length: 107 effective length of database: 57,102,319 effective search space used: 5367617986 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
