ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | baal2e17 |
|---|---|
| Clone Library Name | barley_pub |
>DHGY_CUCSA (P13443) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-dependent| hydroxypyruvate reductase) (HPR) (GDH) Length = 382 Score = 220 bits (560), Expect = 2e-57 Identities = 109/149 (73%), Positives = 125/149 (83%) Frame = +3 Query: 6 PVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEV 185 PVTW+RASSM+EVLREADVISLHPVLDKTT+HL+N E L MKK+A+L+N SRGPVIDE Sbjct: 221 PVTWRRASSMDEVLREADVISLHPVLDKTTFHLVNKESLKAMKKDAILINCSRGPVIDEA 280 Query: 186 ALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNV 365 ALV+HL+ NPMFRVGLDVFEDEPYMKPGLA+MKNA++VPHIASASKWTREGMATLAALNV Sbjct: 281 ALVDHLRDNPMFRVGLDVFEDEPYMKPGLADMKNAIIVPHIASASKWTREGMATLAALNV 340 Query: 366 LVSFLGSMIWLNQSSSPCLLGAEVVVPPS 452 L G +W + + L E V PP+ Sbjct: 341 LGKIKGYPVWSDPNRVEPFLD-ENVSPPA 368
>GYAR_PYRHO (O58320) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 334 Score = 111 bits (277), Expect = 1e-24 Identities = 62/136 (45%), Positives = 84/136 (61%) Frame = +3 Query: 33 MEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN 212 +E++LRE+D + L L + TYHLIN ERL +MKK A+L+N +RG V+D ALV+ LK Sbjct: 198 LEDLLRESDFVVLAVPLTRETYHLINEERLKLMKKTAILINIARGKVVDTNALVKALKEG 257 Query: 213 PMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLVSFLGSMI 392 + GLDVFE+EPY L ++ N V+ PHI SAS REGMA L A N++ G + Sbjct: 258 WIAGAGLDVFEEEPYYNEELFKLDNVVLTPHIGSASFGAREGMAELVAKNLIAFKRGEI- 316 Query: 393 WLNQSSSPCLLGAEVV 440 P L+ EV+ Sbjct: 317 ------PPTLVNREVI 326
>GYAR_THELI (Q9C4M5) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 331 Score = 109 bits (272), Expect = 4e-24 Identities = 56/118 (47%), Positives = 76/118 (64%) Frame = +3 Query: 36 EEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANP 215 E +L+E+D ISLH L K TYH+I + L +MK A+L+N SRG V+D AL++ LK Sbjct: 199 ETLLKESDFISLHVPLTKETYHMIGEKELKLMKPNAILINTSRGAVVDTNALIKALKEGW 258 Query: 216 MFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLVSFLGSM 389 + GLDVFE+EPY L ++KN V+ PHI SA+ REGMA L A N++ G + Sbjct: 259 IAGAGLDVFEEEPYYNEELFKLKNVVLAPHIGSATHEAREGMAELVAKNLIAFAKGEI 316
>GYAR_PYRAB (Q9UYR1) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 335 Score = 109 bits (272), Expect = 4e-24 Identities = 60/136 (44%), Positives = 84/136 (61%) Frame = +3 Query: 33 MEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN 212 ++E+LRE+D + L L+K TYH+IN ERL MMK+ A+L+N +RG VID AL++ LK Sbjct: 199 LDELLRESDFVVLAVPLNKETYHMINEERLKMMKRTAILINVARGKVIDTKALIKALKEG 258 Query: 213 PMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLVSFLGSMI 392 + GLDV+E+EPY L + N V+ PHI SA+ REGMA L A N++ G + Sbjct: 259 WIAGAGLDVYEEEPYYNEELFSLDNVVLTPHIGSATFGAREGMAKLVAENLIAFKRGEV- 317 Query: 393 WLNQSSSPCLLGAEVV 440 P L+ EV+ Sbjct: 318 ------PPTLVNREVL 327
>GYAR_PYRKO (Q5JEZ2) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 333 Score = 108 bits (269), Expect = 9e-24 Identities = 61/137 (44%), Positives = 84/137 (61%) Frame = +3 Query: 30 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 209 S+E++LRE+D + L L K T ++IN ERL +MKK A+LVN +RG V+D AL++ LK Sbjct: 197 SLEDLLRESDFVVLAVPLTKETQYMINEERLRLMKKTAILVNIARGKVVDTKALMKALKE 256 Query: 210 NPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLVSFLGSM 389 + GLDV+E+EPY L +KN V+ PHI SA+ REGMA L A N++ Sbjct: 257 GWIAGAGLDVYEEEPYYNEELFSLKNVVLAPHIGSATYGAREGMAELVARNLIA------ 310 Query: 390 IWLNQSSSPCLLGAEVV 440 + N P L+ EVV Sbjct: 311 -FKNGEVPPTLVNKEVV 326
>GYAR_PYRFU (Q8U3Y2) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 336 Score = 101 bits (251), Expect = 1e-21 Identities = 58/136 (42%), Positives = 80/136 (58%) Frame = +3 Query: 33 MEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN 212 +EEVL+E+D + L L K T ++IN ERL +MK A+LVN +RG V+D AL++ LK Sbjct: 198 LEEVLKESDFVILAVPLTKETMYMINEERLKLMKPTAILVNIARGKVVDTKALIKALKEG 257 Query: 213 PMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLVSFLGSMI 392 + GLDVFE+EPY L + N V+ PHI SA+ RE MA L A N++ G + Sbjct: 258 WIAGAGLDVFEEEPYYNEELFSLDNVVLTPHIGSATFEAREAMAELVARNLIAFKRGEI- 316 Query: 393 WLNQSSSPCLLGAEVV 440 P L+ EV+ Sbjct: 317 ------PPTLVNKEVI 326
>GYAR_AERPE (Q9YAW4) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 335 Score = 95.1 bits (235), Expect = 8e-20 Identities = 58/139 (41%), Positives = 82/139 (58%), Gaps = 2/139 (1%) Frame = +3 Query: 30 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 209 S+E++LRE+D++S+H L T HLI L +MKK A+LVN RG ++D ALV+ L+ Sbjct: 198 SLEDLLRESDILSIHLPLTDETRHLIGESELKLMKKTAILVNTGRGAIVDTGALVKALRE 257 Query: 210 NPMFRVGLDVFEDEPYMKPG--LAEMKNAVVVPHIASASKWTREGMATLAALNVLVSFLG 383 + LDVFE+EP + P L KN V+ PH ASA++ TR MA +AA N++ G Sbjct: 258 GWIAAAALDVFEEEP-LNPNHPLTAFKNVVLAPHAASATRETRLRMAMMAAENLVAFAQG 316 Query: 384 SMIWLNQSSSPCLLGAEVV 440 + P L+ EVV Sbjct: 317 KV-------PPNLVNREVV 328
>TKRA_ENTAG (P58000) 2-ketogluconate reductase (EC 1.1.1.215) (2KR)| (2-ketoaldonate reductase) Length = 323 Score = 95.1 bits (235), Expect = 8e-20 Identities = 51/120 (42%), Positives = 74/120 (61%), Gaps = 1/120 (0%) Frame = +3 Query: 33 MEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN 212 ++ +LRE+D + + L + T+H+I E+LA MK A+L+NA RGPV+DE AL+ LK Sbjct: 193 LDTLLRESDFLCISLPLTEQTHHMIGREQLAKMKPSAILINAGRGPVVDEQALIAALKDK 252 Query: 213 PMFRVGLDVFEDEPY-MKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLVSFLGSM 389 + GLDVFE EP + L + N V +PHI SA+ TR GMA A N++ + G + Sbjct: 253 TIHAAGLDVFEQEPLPVDSELLTLPNVVALPHIGSATHETRYGMARDAVDNLIAALAGKV 312
>TKRA_ECOLI (P37666) 2-ketogluconate reductase (EC 1.1.1.215) (2KR)| (2-ketoaldonate reductase) Length = 324 Score = 92.0 bits (227), Expect = 6e-19 Identities = 51/124 (41%), Positives = 71/124 (57%), Gaps = 1/124 (0%) Frame = +3 Query: 21 RASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEH 200 R ++ +L+E+D + L L T+HL E+ A MK A+ +NA RGPV+DE AL+ Sbjct: 190 RYCDLDTLLQESDFVCLILPLTDETHHLFGAEQFAKMKSSAIFINAGRGPVVDENALIAA 249 Query: 201 LKANPMFRVGLDVFEDEPY-MKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLVSF 377 L+ + GLDVFE EP + L M N V VPHI SA+ TR GMA A N++ + Sbjct: 250 LQKGEIHAAGLDVFEQEPLSVDSPLLSMANVVAVPHIGSATHETRYGMAACAVDNLIDAL 309 Query: 378 LGSM 389 G + Sbjct: 310 QGKV 313
>TKRA_ECO57 (P58220) 2-ketogluconate reductase (EC 1.1.1.215) (2KR)| (2-ketoaldonate reductase) Length = 324 Score = 92.0 bits (227), Expect = 6e-19 Identities = 51/124 (41%), Positives = 71/124 (57%), Gaps = 1/124 (0%) Frame = +3 Query: 21 RASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEH 200 R ++ +L+E+D + L L T+HL E+ A MK A+ +NA RGPV+DE AL+ Sbjct: 190 RYCDLDTLLQESDFVCLILPLTDETHHLFGAEQFAKMKSSAIFINAGRGPVVDENALIAA 249 Query: 201 LKANPMFRVGLDVFEDEPY-MKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLVSF 377 L+ + GLDVFE EP + L M N V VPHI SA+ TR GMA A N++ + Sbjct: 250 LQKGEIHAAGLDVFEQEPLSVDSPLLSMANVVAVPHIGSATHETRYGMAACAVDNLIDAL 309 Query: 378 LGSM 389 G + Sbjct: 310 QGKV 313
>YEAA_SCHPO (O14075) Putative 2-hydroxyacid dehydrogenase UNK4.10 (EC 1.-.-.-)| Length = 334 Score = 86.3 bits (212), Expect = 4e-17 Identities = 44/112 (39%), Positives = 69/112 (61%) Frame = +3 Query: 30 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 209 S +++L ++DV+SL+ L+ T H+I MK+ V+VN +RG V+DE ALVE L Sbjct: 202 SFDDLLAKSDVLSLNLPLNAHTRHIIGKPEFQKMKRGIVIVNTARGAVMDEAALVEALDE 261 Query: 210 NPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNV 365 ++ GLDVFE+EP + PGL E + +++PH+ + S T+ M +NV Sbjct: 262 GIVYSAGLDVFEEEPKIHPGLLENEKVILLPHLGTNSLETQYKMECAVLMNV 313
>SERA_METTH (O27051) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 525 Score = 83.6 bits (205), Expect = 2e-16 Identities = 43/119 (36%), Positives = 68/119 (57%) Frame = +3 Query: 27 SSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLK 206 + +E +LRE+D++++H L T HLI+ + +MK A +VN +RG +IDE AL LK Sbjct: 187 TDLETLLRESDIVTIHVPLTPETRHLISEDEFKLMKDTAFIVNCARGGIIDEDALYRALK 246 Query: 207 ANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLVSFLG 383 + LDVFE+EP L E++N V+ PHI +++ + A + A + F G Sbjct: 247 DGEIAGAALDVFEEEPPEGSPLLELENVVLTPHIGASTSEAQRDAAIIVANEIKTVFQG 305
>YN14_YEAST (P53839) Putative 2-hydroxyacid dehydrogenase YNL274C (EC 1.-.-.-)| Length = 350 Score = 82.4 bits (202), Expect = 5e-16 Identities = 43/109 (39%), Positives = 65/109 (59%) Frame = +3 Query: 36 EEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANP 215 EE L+ +D++S++ L+ T+HLIN E + MK V+VN +RG VIDE A+ + L++ Sbjct: 212 EEFLKRSDIVSVNVPLNHNTHHLINAETIEKMKDGVVIVNTARGAVIDEQAMTDALRSGK 271 Query: 216 MFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALN 362 + GLDVFE EP + L M + +PH+ + S TR+ M L N Sbjct: 272 IRSAGLDVFEYEPKISKELLSMSQVLGLPHMGTHSVETRKKMEELVVEN 320
>Y1556_HAEIN (P45250) Putative 2-hydroxyacid dehydrogenase HI1556 (EC 1.-.-.-)| Length = 315 Score = 82.0 bits (201), Expect = 7e-16 Identities = 46/100 (46%), Positives = 61/100 (61%), Gaps = 5/100 (5%) Frame = +3 Query: 36 EEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANP 215 +EVL++AD+++LH L +TT LIN E L+ MKK A L+N RGP+IDE+ALV+ LK Sbjct: 191 DEVLKQADIVTLHCPLTETTKDLINAETLSKMKKGAFLINTGRGPLIDELALVDALKTGH 250 Query: 216 MFRVGLDVFEDEPYMKP-----GLAEMKNAVVVPHIASAS 320 + LDV EP K M N ++ PHIA AS Sbjct: 251 LGGAALDVMVKEPPEKDNPLILAAKTMPNLIITPHIAWAS 290
>SERA_METJA (Q58424) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 524 Score = 80.1 bits (196), Expect = 3e-15 Identities = 41/108 (37%), Positives = 64/108 (59%) Frame = +3 Query: 33 MEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN 212 + E+ + AD I+LH L T H+I E++A+MKK A++VN +RG +IDE AL E LK Sbjct: 188 INELCKRADFITLHVPLTPKTRHIIGREQIALMKKNAIIVNCARGGLIDEKALYEALKEG 247 Query: 213 PMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAA 356 + LDVFE+EP L + N + PH ++++ ++ T+ A Sbjct: 248 KIRAAALDVFEEEPPKDNPLLTLDNVIGTPHQGASTEEAQKAAGTIVA 295
>TKRA_BACSU (O32264) Probable 2-ketogluconate reductase (EC 1.1.1.215) (2KR)| Length = 325 Score = 77.4 bits (189), Expect = 2e-14 Identities = 43/120 (35%), Positives = 65/120 (54%), Gaps = 1/120 (0%) Frame = +3 Query: 27 SSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLK 206 + ++ +L ++D I L L TYH+I +MK A+ VN SRG +DE AL+ L+ Sbjct: 195 AELDTLLEQSDFILLITPLTDETYHMIGEREFKLMKNSAIFVNISRGKTVDEKALIRALQ 254 Query: 207 ANPMFRVGLDVFEDEPYMKPG-LAEMKNAVVVPHIASASKWTREGMATLAALNVLVSFLG 383 + GLDV+E EP + L ++ N ++PHI SA+ R M AA N+L + G Sbjct: 255 EGWIRGAGLDVYEKEPVTQDNPLLQLDNVTLLPHIGSATAKVRFNMCKQAAENMLAAIQG 314
>PDXB_PHOLL (Q7N2B2) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 375 Score = 76.3 bits (186), Expect = 4e-14 Identities = 48/124 (38%), Positives = 73/124 (58%), Gaps = 6/124 (4%) Frame = +3 Query: 30 SMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 197 S+E++++EAD+++ H L+K+ T+HL++ E L+++ +L+NASRG VID AL+ Sbjct: 160 SLEKLVKEADILTFHTPLNKSGPYKTHHLVDVELLSVLPDNRILINASRGEVIDNQALLT 219 Query: 198 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA--TLAALNVLV 371 LK RV LDV+E EP + L E+ + + PHIA +T EG A T Sbjct: 220 ALKCGKKLRVVLDVWEPEPDLSLPLLELVD-IGTPHIAG---YTLEGKARGTTQVFEAYC 275 Query: 372 SFLG 383 FLG Sbjct: 276 EFLG 279
>SERA_BACSU (P35136) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 525 Score = 76.3 bits (186), Expect = 4e-14 Identities = 48/145 (33%), Positives = 76/145 (52%), Gaps = 1/145 (0%) Frame = +3 Query: 30 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 209 + EEVL AD+I++H L K T L+N E +A KK L+N +RG +IDE AL+E L+ Sbjct: 185 TFEEVLESADIITVHTPLTKETKGLLNKETIAKTKKGVRLINCARGGIIDEAALLEALEN 244 Query: 210 NPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLVSFLGSM 389 + LDVFE EP + L + + PH+ +++K + +A + VL F + Sbjct: 245 GHVAGAALDVFEVEPPVDNKLVDHPLVIATPHLGASTKEAQLNVAAQVSEEVL-QFAKGL 303 Query: 390 IWLNQSSSPCLLGAEVV-VPPSHNI 461 ++ + P + E + P H I Sbjct: 304 PVMSAINLPAMTKDEFAKIKPYHQI 328
>DHGY_METEX (Q59516) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-dependent| hydroxypyruvate reductase) (HPR) (GDH) (Hydroxypyruvate dehydrogenase) (Glyoxylate reductase) (HPR-A) Length = 313 Score = 75.5 bits (184), Expect = 6e-14 Identities = 43/110 (39%), Positives = 65/110 (59%), Gaps = 3/110 (2%) Frame = +3 Query: 33 MEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN 212 +E +L ++DVI+LH L T ++I E+L MK+ A+L+N +RG ++DE AL++ LK Sbjct: 186 LETILTQSDVITLHVPLTPDTKNMIGAEQLKKMKRSAILINTARGGLVDEAALLQALKDG 245 Query: 213 PMFRVGLDVFEDEPYMKPGL---AEMKNAVVVPHIASASKWTREGMATLA 353 + G DV EP + A++ N +V PH+A ASK E M LA Sbjct: 246 TIGGAGFDVVAQEPPKDGNILCDADLPNLIVTPHVAWASK---EAMQILA 292
>SERA_ARATH (O04130) D-3-phosphoglycerate dehydrogenase, chloroplast precursor| (EC 1.1.1.95) (3-PGDH) Length = 624 Score = 74.3 bits (181), Expect = 1e-13 Identities = 45/121 (37%), Positives = 66/121 (54%), Gaps = 1/121 (0%) Frame = +3 Query: 30 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 209 S ++ + AD +SLH L T + N E + MKK L+N +RG VIDE ALV L A Sbjct: 268 SFDQAISTADFVSLHMPLTPATKKVFNDETFSKMKKGVRLINVARGGVIDEDALVRALDA 327 Query: 210 NPMFRVGLDVFEDEPYMKPG-LAEMKNAVVVPHIASASKWTREGMATLAALNVLVSFLGS 386 + + LDVF +EP K L + +N V PH+ +++K +EG+A A V + G Sbjct: 328 GIVAQAALDVFCEEPPSKDSRLIQHENVTVTPHLGASTKEAQEGVAIEIAEAVAGALKGE 387 Query: 387 M 389 + Sbjct: 388 L 388
>SERA_MYCLE (O33116) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 528 Score = 74.3 bits (181), Expect = 1e-13 Identities = 41/121 (33%), Positives = 67/121 (55%) Frame = +3 Query: 30 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 209 S +++L AD IS+H T LI+ E LA K ++VNA+RG ++DEVAL + +++ Sbjct: 188 SFDDLLARADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLVDEVALADAVRS 247 Query: 210 NPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLVSFLGSM 389 + GLDVF EP L E+ VV PH+ +++ ++ T A +V ++ G Sbjct: 248 GHVRAAGLDVFATEPCTDSPLFELSQVVVTPHLGASTAEAQDRAGTDVAESVRLALAGEF 307 Query: 390 I 392 + Sbjct: 308 V 308
>PDXB_PSEPK (Q88L20) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 380 Score = 72.4 bits (176), Expect = 5e-13 Identities = 50/122 (40%), Positives = 67/122 (54%), Gaps = 4/122 (3%) Frame = +3 Query: 30 SMEEVLREADVISLHPVLDK----TTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 197 S+E +L++ DVISLH L + T+HL+ +LA ++ A LVNASRGPV+D VAL E Sbjct: 159 SLETILQQCDVISLHTPLQRGGQHPTWHLLGQAQLAQLRPGAWLVNASRGPVVDNVALRE 218 Query: 198 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLVSF 377 L LDV+E EP + LA++ + PHIA S R+ T L F Sbjct: 219 LLLDREDVHAVLDVWEGEPQVDLQLADL-CTLATPHIAGYSLDGRQ-RGTARIYQALCRF 276 Query: 378 LG 383 LG Sbjct: 277 LG 278
>PDXB_VIBVY (Q7MIT6) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 377 Score = 72.4 bits (176), Expect = 5e-13 Identities = 47/126 (37%), Positives = 70/126 (55%), Gaps = 6/126 (4%) Frame = +3 Query: 27 SSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALV 194 +S++ +L+EADVI+LH + + T+HLIN E L ++ + +L+NA+RGPV+D AL Sbjct: 160 TSLDRLLQEADVITLHTPITRDGKYPTHHLINKEILNSLRADQILINAARGPVVDNQALK 219 Query: 195 EHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA--TLAALNVL 368 L+ F LDVFE EP + L + A PH+A + EG A T N Sbjct: 220 HRLQQADGFTAALDVFEFEPEVDMELLPLL-AFATPHVAG---YGLEGKARGTTMIFNSY 275 Query: 369 VSFLGS 386 F+G+ Sbjct: 276 CEFIGN 281
>PDXB_VIBVU (Q8DB36) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 377 Score = 72.4 bits (176), Expect = 5e-13 Identities = 47/126 (37%), Positives = 70/126 (55%), Gaps = 6/126 (4%) Frame = +3 Query: 27 SSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALV 194 +S++ +L+EADVI+LH + + T+HLIN E L ++ + +L+NA+RGPV+D AL Sbjct: 160 TSLDRLLQEADVITLHTPITRDGKYPTHHLINEEILNSLRADQILINAARGPVVDNQALK 219 Query: 195 EHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA--TLAALNVL 368 L+ F LDVFE EP + L + A PH+A + EG A T N Sbjct: 220 RRLQQADGFMAALDVFEFEPEVDMELLPLL-AFATPHVAG---YGLEGKARGTTMIFNSY 275 Query: 369 VSFLGS 386 F+G+ Sbjct: 276 CEFIGN 281
>SERA_MYCTU (P0A544) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 528 Score = 72.0 bits (175), Expect = 7e-13 Identities = 40/121 (33%), Positives = 65/121 (53%) Frame = +3 Query: 30 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 209 S++++L AD IS+H T LI+ E LA K ++VNA+RG ++DE AL + + Sbjct: 188 SLDDLLARADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLVDEAALADAITG 247 Query: 210 NPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLVSFLGSM 389 + GLDVF EP L E+ VV PH+ +++ ++ T A +V ++ G Sbjct: 248 GHVRAAGLDVFATEPCTDSPLFELAQVVVTPHLGASTAEAQDRAGTDVAESVRLALAGEF 307 Query: 390 I 392 + Sbjct: 308 V 308
>SERA_MYCBO (P0A545) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 528 Score = 72.0 bits (175), Expect = 7e-13 Identities = 40/121 (33%), Positives = 65/121 (53%) Frame = +3 Query: 30 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 209 S++++L AD IS+H T LI+ E LA K ++VNA+RG ++DE AL + + Sbjct: 188 SLDDLLARADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLVDEAALADAITG 247 Query: 210 NPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLVSFLGSM 389 + GLDVF EP L E+ VV PH+ +++ ++ T A +V ++ G Sbjct: 248 GHVRAAGLDVFATEPCTDSPLFELAQVVVTPHLGASTAEAQDRAGTDVAESVRLALAGEF 307 Query: 390 I 392 + Sbjct: 308 V 308
>SERA_HAEIN (P43885) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 410 Score = 71.6 bits (174), Expect = 9e-13 Identities = 41/114 (35%), Positives = 66/114 (57%), Gaps = 6/114 (5%) Frame = +3 Query: 18 KRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 197 K+ S+EE+L DV+SLH +T +L+N R+A +K+ A+L+NA+RG V+D AL + Sbjct: 193 KQVRSLEELLSSCDVVSLHVPELPSTKNLMNVARIAQLKQGAILINAARGTVVDIDALAQ 252 Query: 198 HLKANPMFRVGLDVFEDEP------YMKPGLAEMKNAVVVPHIASASKWTREGM 341 LK + +DVF EP ++ P L E N ++ PHI ++ +E + Sbjct: 253 ALKDGKLQGAAIDVFPVEPASINEEFISP-LREFDNVILTPHIGGSTAEAQENI 305
>PDXB_VIBCH (Q9KQ92) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 381 Score = 71.6 bits (174), Expect = 9e-13 Identities = 49/134 (36%), Positives = 71/134 (52%), Gaps = 6/134 (4%) Frame = +3 Query: 27 SSMEEVLREADVISLHPVLDK----TTYHLINPERLAMMKKEAVLVNASRGPVIDEVALV 194 + +E +L++ADVI+LH + + T+HLI+ L ++ + +L+NA+RGPV+D AL Sbjct: 160 TELETLLKQADVITLHTPITRGGEWPTHHLIDAAILEQLRSDQILINAARGPVVDNAALK 219 Query: 195 EHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA--TLAALNVL 368 L+ F LDVFE EP + L + A PHIA + EG A T N Sbjct: 220 ARLQQGDGFTAVLDVFEFEPQVDMELLPLL-AFATPHIAG---YGLEGKARGTTMIFNSY 275 Query: 369 VSFLGSMIWLNQSS 410 FLGS N +S Sbjct: 276 CEFLGSAHCANPAS 289
>SERA_SYNY3 (P73821) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 554 Score = 70.9 bits (172), Expect = 2e-12 Identities = 41/117 (35%), Positives = 63/117 (53%) Frame = +3 Query: 33 MEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN 212 ++ + EAD I+LH T +LIN E LA MK A ++N SRG +IDE ALV ++ Sbjct: 215 LDLLFSEADFITLHIPKTPETANLINAETLAKMKPTARIINCSRGGIIDEEALVTAIETA 274 Query: 213 PMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLVSFLG 383 + LDVF EP + L E N ++ PH+ ++++ + +A A + LG Sbjct: 275 QIGGAALDVFAQEPLGESRLREFSNVILTPHLGASTEEAQVNVAVDVAEQIRDVLLG 331
>PDXB_PSEAE (Q9I3W9) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 380 Score = 70.9 bits (172), Expect = 2e-12 Identities = 45/101 (44%), Positives = 58/101 (57%), Gaps = 4/101 (3%) Frame = +3 Query: 30 SMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 197 S+E +L EADVISLH L++ T HL++ RLA ++ LVNASRG V+D AL Sbjct: 160 SLERLLAEADVISLHTPLNRDGEHPTRHLLDEPRLAALRPGTWLVNASRGAVVDNQALRR 219 Query: 198 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 320 L+ V LDV+E EP P LA + + PHIA S Sbjct: 220 LLEGGADLEVALDVWEGEPQADPELA-ARCLIATPHIAGYS 259
>PDXB_PSESM (Q884R9) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 380 Score = 70.5 bits (171), Expect = 2e-12 Identities = 46/121 (38%), Positives = 69/121 (57%), Gaps = 4/121 (3%) Frame = +3 Query: 30 SMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 197 S++E+L+ DVISLH LDK+ T+HL++ RL +++ A L+NASRG V+D AL + Sbjct: 159 SLDEILQRCDVISLHTPLDKSGQSPTWHLLDEARLRQLRQGAWLINASRGAVVDNRALHD 218 Query: 198 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLVSF 377 + + LDV+E EP + LA++ + PHIA S R+ T L +F Sbjct: 219 VMLEREDLQAVLDVWEGEPQVNVALADL-CVIGTPHIAGYSLDGRQ-RGTAQIYQALCTF 276 Query: 378 L 380 L Sbjct: 277 L 277
>CTBP2_MOUSE (P56546) C-terminal-binding protein 2 (CtBP2)| Length = 445 Score = 69.3 bits (168), Expect = 4e-12 Identities = 42/116 (36%), Positives = 66/116 (56%), Gaps = 6/116 (5%) Frame = +3 Query: 18 KRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 197 +R +++++L ++D +SLH L++ +HLIN + M++ A LVNA+RG ++DE AL + Sbjct: 224 QRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLVDEKALAQ 283 Query: 198 HLKANPMFRVGLDVFEDEP--YMKPGLAEMKNAVVVPHIA----SASKWTREGMAT 347 LK + LDV E EP + + L + N + PH A AS RE AT Sbjct: 284 ALKEGRIRGAALDVHESEPFSFAQGPLKDAPNLICTPHTAWYSEQASLEMREAAAT 339
>CTBP2_HUMAN (P56545) C-terminal-binding protein 2 (CtBP2)| Length = 445 Score = 69.3 bits (168), Expect = 4e-12 Identities = 42/116 (36%), Positives = 66/116 (56%), Gaps = 6/116 (5%) Frame = +3 Query: 18 KRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 197 +R +++++L ++D +SLH L++ +HLIN + M++ A LVNA+RG ++DE AL + Sbjct: 224 QRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLVDEKALAQ 283 Query: 198 HLKANPMFRVGLDVFEDEP--YMKPGLAEMKNAVVVPHIA----SASKWTREGMAT 347 LK + LDV E EP + + L + N + PH A AS RE AT Sbjct: 284 ALKEGRIRGAALDVHESEPFSFAQGPLKDAPNLICTPHTAWYSEQASLEMREAAAT 339
>PDXB_WIGBR (Q8D2P6) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 68.6 bits (166), Expect = 8e-12 Identities = 46/127 (36%), Positives = 72/127 (56%), Gaps = 6/127 (4%) Frame = +3 Query: 21 RASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVA 188 + S+ E+++ +D+I+LH L + T+HLIN + L +K +L+N SRG VID + Sbjct: 156 KLKSLNEIVQNSDIITLHVPLTYSGKYPTWHLINKKILLDLKDNCILINTSRGSVIDNNS 215 Query: 189 LVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREG--MATLAALN 362 L+ LK RV LDV+E+EP + L + + + PHIA S EG T++ N Sbjct: 216 LLNILKEGKPIRVVLDVWENEPLICSKLLSLID-IGTPHIAGHS---LEGKIKGTISIFN 271 Query: 363 VLVSFLG 383 L +F+G Sbjct: 272 SLCNFVG 278
>CTBP_DROME (O46036) C-terminal-binding protein (CtBP protein) (dCtBP)| Length = 476 Score = 68.2 bits (165), Expect = 1e-11 Identities = 38/125 (30%), Positives = 68/125 (54%), Gaps = 2/125 (1%) Frame = +3 Query: 21 RASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEH 200 R +++++L ++D +SLH L++ +HLIN + M+ A LVN +RG ++D+ L Sbjct: 219 RVYTLQDLLFQSDCVSLHCTLNEHNHHLINEFTIKQMRPGAFLVNTARGGLVDDETLALA 278 Query: 201 LKANPMFRVGLDVFEDEPY--MKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLVS 374 LK + LDV E+EPY + L + N + PH A S + + +AA + + Sbjct: 279 LKQGRIRAAALDVHENEPYNVFQGALKDAPNLICTPHAAFFSDASATELREMAATEIRRA 338 Query: 375 FLGSM 389 +G++ Sbjct: 339 IVGNI 343
>SERA_ARCFU (O29445) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 527 Score = 67.4 bits (163), Expect = 2e-11 Identities = 37/112 (33%), Positives = 63/112 (56%), Gaps = 1/112 (0%) Frame = +3 Query: 36 EEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANP 215 + +L +DVI++H K T LI + MK ++VNA+RG ++DE AL E +KA Sbjct: 188 DTLLASSDVITVHVPRTKETIGLIGKGQFEKMKDGVIVVNAARGGIVDEAALYEAIKAGK 247 Query: 216 MFRVGLDVFEDEPYMKPG-LAEMKNAVVVPHIASASKWTREGMATLAALNVL 368 + LDV+E EP L ++ N V PHIA++++ + + + A +++ Sbjct: 248 VAAAALDVYEKEPPSPDNPLLKLDNVVTTPHIAASTREAQLNVGMIIAEDIV 299
>GRHPR_HUMAN (Q9UBQ7) Glyoxylate reductase/hydroxypyruvate reductase (EC| 1.1.1.79) Length = 328 Score = 67.0 bits (162), Expect = 2e-11 Identities = 43/119 (36%), Positives = 62/119 (52%), Gaps = 1/119 (0%) Frame = +3 Query: 30 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 209 S E+ ++D I + L T L N + MK+ AV +N SRG V+++ L + L + Sbjct: 201 STPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALAS 260 Query: 210 NPMFRVGLDVFEDEPY-MKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLVSFLG 383 + GLDV EP L +KN V++PHI SA+ TR M+ LAA N+L G Sbjct: 261 GKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNTMSLLAANNLLAGLRG 319
>CTBPA_XENLA (Q9YHU0) C-terminal-binding protein A (CtBP)| Length = 440 Score = 66.6 bits (161), Expect = 3e-11 Identities = 40/124 (32%), Positives = 67/124 (54%), Gaps = 2/124 (1%) Frame = +3 Query: 18 KRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 197 +R S+++++L +D ++LH L++ +HLIN + M++ A LVN +RG ++DE AL + Sbjct: 218 QRVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTIKQMRQGAFLVNTARGGLVDEKALAQ 277 Query: 198 HLKANPMFRVGLDVFEDEP--YMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLV 371 LK + LDV E EP + + L + N + PH A S+ M AA + Sbjct: 278 ALKEGRIRGAALDVHESEPFSFTQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIRR 337 Query: 372 SFLG 383 + G Sbjct: 338 AITG 341
>CTBP1_RAT (Q9Z2F5) C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1)| (C-terminal-binding protein 3) (CtBP3) (50 kDa BFA-dependent ADP-ribosylation substrate) (BARS-50) Length = 430 Score = 66.2 bits (160), Expect = 4e-11 Identities = 40/124 (32%), Positives = 67/124 (54%), Gaps = 2/124 (1%) Frame = +3 Query: 18 KRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 197 +R S+++++L +D ++LH L++ +HLIN + M++ A LVN +RG ++DE AL + Sbjct: 207 QRVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQ 266 Query: 198 HLKANPMFRVGLDVFEDEP--YMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLV 371 LK + LDV E EP + + L + N + PH A S+ M AA + Sbjct: 267 ALKEGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIRR 326 Query: 372 SFLG 383 + G Sbjct: 327 AITG 330
>CTBP1_MOUSE (O88712) C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1)| Length = 440 Score = 66.2 bits (160), Expect = 4e-11 Identities = 40/124 (32%), Positives = 67/124 (54%), Gaps = 2/124 (1%) Frame = +3 Query: 18 KRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 197 +R S+++++L +D ++LH L++ +HLIN + M++ A LVN +RG ++DE AL + Sbjct: 218 QRVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQ 277 Query: 198 HLKANPMFRVGLDVFEDEP--YMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLV 371 LK + LDV E EP + + L + N + PH A S+ M AA + Sbjct: 278 ALKEGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIRR 337 Query: 372 SFLG 383 + G Sbjct: 338 AITG 341
>CTBP1_HUMAN (Q13363) C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1)| Length = 440 Score = 66.2 bits (160), Expect = 4e-11 Identities = 40/124 (32%), Positives = 67/124 (54%), Gaps = 2/124 (1%) Frame = +3 Query: 18 KRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 197 +R S+++++L +D ++LH L++ +HLIN + M++ A LVN +RG ++DE AL + Sbjct: 218 QRVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQ 277 Query: 198 HLKANPMFRVGLDVFEDEP--YMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLV 371 LK + LDV E EP + + L + N + PH A S+ M AA + Sbjct: 278 ALKEGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIRR 337 Query: 372 SFLG 383 + G Sbjct: 338 AITG 341
>YPRB2_CORML (P0C1E9) Hypothetical protein in proB 3'region (EC 1.-.-.-)| Length = 304 Score = 65.9 bits (159), Expect = 5e-11 Identities = 43/111 (38%), Positives = 55/111 (49%), Gaps = 1/111 (0%) Frame = +3 Query: 36 EEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANP 215 E V EADV L L TY ++N E L MK AVLVN RGP+I+ LV+ L Sbjct: 175 EHVWAEADVFVLILPLTDATYQIVNAETLGKMKPSAVLVNVGRGPLINTDDLVDALNNGT 234 Query: 216 MFRVGLDVFEDEPYM-KPGLAEMKNAVVVPHIASASKWTREGMATLAALNV 365 + LDV + EP L EM N V+ PH A+ ++ R L N+ Sbjct: 235 IAGAALDVTDPEPLPDSHPLWEMDNVVITPHTANTNERIRALTGELTLRNI 285
>LDHD_TREPA (O83080) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 331 Score = 65.5 bits (158), Expect = 6e-11 Identities = 43/123 (34%), Positives = 60/123 (48%), Gaps = 14/123 (11%) Frame = +3 Query: 15 WKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALV 194 W SM+E+L +DVISLH K ++HLIN + +A MK LVN +RG VID AL+ Sbjct: 186 WLTYVSMDELLSTSDVISLHMPATKDSHHLINAKTIAQMKDGVYLVNTARGAVIDSQALL 245 Query: 195 EHLKANPMFRVGLDVFEDE-PYMKPG-------------LAEMKNAVVVPHIASASKWTR 332 + L + LD +E E PY+ L + + PHIA ++ Sbjct: 246 DSLDKGKIAGAALDAYEFEGPYIPKDNGNNPITDTVYARLVAHERIIYTPHIAFYTETAI 305 Query: 333 EGM 341 E M Sbjct: 306 ENM 308
>PDXB_SALTY (P60802) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 65.1 bits (157), Expect = 8e-11 Identities = 44/124 (35%), Positives = 66/124 (53%), Gaps = 6/124 (4%) Frame = +3 Query: 30 SMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 197 +++E+++EADV++ H L K T HL + + +K A+L+NA RGPV+D AL+ Sbjct: 160 TLDELVQEADVLTFHTPLYKDGPYKTLHLADETLIRRLKPGAILINACRGPVVDNAALLA 219 Query: 198 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA--TLAALNVLV 371 L A V LDV+E EP + L E + + HIA +T EG A T Sbjct: 220 RLNAGQPLSVVLDVWEGEPDLNVALLEAVD-IGTSHIAG---YTLEGKARGTTQVFEAYS 275 Query: 372 SFLG 383 +F+G Sbjct: 276 AFIG 279
>PDXB_SALTI (P60801) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 65.1 bits (157), Expect = 8e-11 Identities = 44/124 (35%), Positives = 66/124 (53%), Gaps = 6/124 (4%) Frame = +3 Query: 30 SMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 197 +++E+++EADV++ H L K T HL + + +K A+L+NA RGPV+D AL+ Sbjct: 160 TLDELVQEADVLTFHTPLYKDGPYKTLHLADETLIRRLKPGAILINACRGPVVDNAALLA 219 Query: 198 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA--TLAALNVLV 371 L A V LDV+E EP + L E + + HIA +T EG A T Sbjct: 220 RLNAGQPLSVVLDVWEGEPDLNVALLEAVD-IGTSHIAG---YTLEGKARGTTQVFEAYS 275 Query: 372 SFLG 383 +F+G Sbjct: 276 AFIG 279
>PTXD_PSEST (O69054) Phosphonate dehydrogenase (EC 1.20.1.1) (NAD-dependent| phosphite dehydrogenase) Length = 336 Score = 65.1 bits (157), Expect = 8e-11 Identities = 42/130 (32%), Positives = 64/130 (49%), Gaps = 8/130 (6%) Frame = +3 Query: 21 RASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEH 200 R + E+ +D I L L+ T HL+N E LA+++ A+LVN RG V+DE A++ Sbjct: 190 RQVACSELFASSDFILLALPLNADTQHLVNAELLALVRPGALLVNPCRGSVVDEAAVLAA 249 Query: 201 LKANPMFRVGLDVFEDEPYMK--------PGLAEMKNAVVVPHIASASKWTREGMATLAA 356 L+ + DVFE E + + P L N + PHI SA + R + AA Sbjct: 250 LERGQLGGYAADVFEMEDWARADRPRLIDPALLAHPNTLFTPHIGSAVRAVRLEIERCAA 309 Query: 357 LNVLVSFLGS 386 N++ G+ Sbjct: 310 QNIIQVLAGA 319
>DDH_ZYMMO (P30799) 2-hydroxyacid dehydrogenase homolog (EC 1.1.1.-)| Length = 331 Score = 65.1 bits (157), Expect = 8e-11 Identities = 33/77 (42%), Positives = 49/77 (63%) Frame = +3 Query: 21 RASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEH 200 R +S++EV+ +D+ISLH L +H+IN E LA KK LVN SRG ++D A+++ Sbjct: 189 RFTSLDEVIETSDIISLHCPLTPENHHMINEETLARAKKGFYLVNTSRGGLVDTKAVIKS 248 Query: 201 LKANPMFRVGLDVFEDE 251 LKA + DV+E+E Sbjct: 249 LKAKHLGGYAADVYEEE 265
>Y2355_CORGL (P0C1E8) Hypothetical protein Cgl2355/cg2587 (EC 1.-.-.-)| Length = 304 Score = 64.7 bits (156), Expect = 1e-10 Identities = 42/111 (37%), Positives = 55/111 (49%), Gaps = 1/111 (0%) Frame = +3 Query: 36 EEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANP 215 E V EADV L L TY ++N E L MK AV+VN RGP+I+ LV+ L Sbjct: 175 EHVWAEADVFVLILPLTDATYQIVNAETLGKMKPSAVVVNVGRGPLINTDDLVDALNNGT 234 Query: 216 MFRVGLDVFEDEPYM-KPGLAEMKNAVVVPHIASASKWTREGMATLAALNV 365 + LDV + EP L EM N V+ PH A+ ++ R L N+ Sbjct: 235 IAGAALDVTDPEPLPDSHPLWEMDNVVITPHTANTNERIRALTGELTLRNI 285
>CTBPB_XENLA (Q9W758) C-terminal-binding protein B (TCF-3 corepressor CtBP)| (XCtBP) Length = 437 Score = 64.7 bits (156), Expect = 1e-10 Identities = 35/100 (35%), Positives = 58/100 (58%), Gaps = 2/100 (2%) Frame = +3 Query: 18 KRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 197 +R ++++E+L +D I+LH L++ +HLIN + M++ LVN +RG ++DE AL + Sbjct: 221 QRMATLQELLMHSDCITLHCNLNEHNHHLINDFTIKQMRQGCFLVNTARGGLVDEKALAQ 280 Query: 198 HLKANPMFRVGLDVFEDEP--YMKPGLAEMKNAVVVPHIA 311 LK + LDV E EP + + L + N + PH A Sbjct: 281 ALKDGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHTA 320
>GRHPR_MOUSE (Q91Z53) Glyoxylate reductase/hydroxypyruvate reductase (EC| 1.1.1.79) Length = 328 Score = 63.9 bits (154), Expect = 2e-10 Identities = 41/117 (35%), Positives = 62/117 (52%), Gaps = 2/117 (1%) Frame = +3 Query: 39 EVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPM 218 ++ E+D I + L T L + + MK A+ +N SRG V+++ L + L + + Sbjct: 204 QLAAESDFIVVSCSLTPDTMGLCSKDFFQKMKNTAIFINISRGDVVNQEDLYQALASGQI 263 Query: 219 FRVGLDVFEDEPYMKPG--LAEMKNAVVVPHIASASKWTREGMATLAALNVLVSFLG 383 GLDV EP + P L +KN V++PHI SA+ TR M+ LAA N+L G Sbjct: 264 AAAGLDVTTPEP-LPPSHPLLTLKNCVILPHIGSATYKTRNTMSLLAANNLLAGLRG 319
>PDXB_YERPS (Q668W7) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 375 Score = 63.5 bits (153), Expect = 2e-10 Identities = 42/109 (38%), Positives = 63/109 (57%), Gaps = 5/109 (4%) Frame = +3 Query: 33 MEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEH 200 +E+++READV++ H L+KT + H+ + E LA + +L+NA RG V+D AL+ Sbjct: 161 LEKLVREADVLTFHTPLNKTGAYQSLHMADDELLAALPDGRILINACRGAVVDNAALLRA 220 Query: 201 LKANPMFRVGLDVFEDEPYMK-PGLAEMKNAVVVPHIASASKWTREGMA 344 L+ V LDV+E EP + P LA + + PHIA +T EG A Sbjct: 221 LEKGKKLSVVLDVWEPEPDLSLPLLARVD--IGTPHIAG---YTLEGKA 264
>PDXB_YERPE (Q8D0U3) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 375 Score = 63.5 bits (153), Expect = 2e-10 Identities = 42/109 (38%), Positives = 63/109 (57%), Gaps = 5/109 (4%) Frame = +3 Query: 33 MEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEH 200 +E+++READV++ H L+KT + H+ + E LA + +L+NA RG V+D AL+ Sbjct: 161 LEKLVREADVLTFHTPLNKTGAYQSLHMADDELLAALPDGRILINACRGAVVDNAALLRA 220 Query: 201 LKANPMFRVGLDVFEDEPYMK-PGLAEMKNAVVVPHIASASKWTREGMA 344 L+ V LDV+E EP + P LA + + PHIA +T EG A Sbjct: 221 LEKGKKLSVVLDVWEPEPDLSLPLLARVD--IGTPHIAG---YTLEGKA 264
>LDHD_LACDE (P26297) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 332 Score = 63.5 bits (153), Expect = 2e-10 Identities = 29/74 (39%), Positives = 49/74 (66%) Frame = +3 Query: 30 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 209 S++++ ++ADVISLH H+IN + +A MK++ V+VN SRGP++D A++ L + Sbjct: 191 SLDDLYKQADVISLHVPDVPANVHMINDKSIAKMKQDVVIVNVSRGPLVDTDAVIRGLDS 250 Query: 210 NPMFRVGLDVFEDE 251 +F +DV+E E Sbjct: 251 GKVFGYAMDVYEGE 264
>SERA_SCHPO (P87228) Putative D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95)| (3-PGDH) Length = 466 Score = 63.5 bits (153), Expect = 2e-10 Identities = 37/115 (32%), Positives = 59/115 (51%), Gaps = 13/115 (11%) Frame = +3 Query: 18 KRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 197 K+ SS+ E+L AD +SLH T ++I+ + A MK+ + L+NASRG V+D ALV+ Sbjct: 236 KQLSSLPELLHRADFVSLHVPASPETKNMISSKEFAAMKEGSYLINASRGTVVDIPALVD 295 Query: 198 HLKANPMFRVGLDVFEDEP-------------YMKPGLAEMKNAVVVPHIASASK 323 K+ + +DV+ EP L KN ++ PHI +++ Sbjct: 296 ASKSGKIAGAAIDVYPSEPAGNGKDKFVDSLNSWTSELTHCKNIILTPHIGGSTE 350
>PDXB_VIBPA (Q87MN8) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 377 Score = 63.2 bits (152), Expect = 3e-10 Identities = 35/97 (36%), Positives = 57/97 (58%), Gaps = 4/97 (4%) Frame = +3 Query: 33 MEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEH 200 + E++ ++D+I+LH + K T+HLI+ + L ++ + +L+NA+RGPV+D AL + Sbjct: 162 LAELIEQSDIITLHTPITKDGLHPTHHLIDEKVLNGLRGDQILINAARGPVVDNQALKQR 221 Query: 201 LKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIA 311 L F LDVFE EP + L + A PH+A Sbjct: 222 LMKQDGFTAALDVFEFEPEVDMELLPLL-AFATPHVA 257
>PDXB_SHEON (Q8ECR2) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 376 Score = 62.0 bits (149), Expect = 7e-10 Identities = 39/101 (38%), Positives = 54/101 (53%), Gaps = 4/101 (3%) Frame = +3 Query: 30 SMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 197 S+E +L+EAD+ISLH + +T T HL + RL +K L+N RG VID AL++ Sbjct: 161 SLETLLQEADIISLHVPITRTGEHKTLHLFDEARLMSLKANIWLINCCRGDVIDNQALIK 220 Query: 198 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 320 + ++ LDV+E EP P L PHIA S Sbjct: 221 VKQQRDDLKLVLDVWEGEPNPMPELVPFAE-FATPHIAGYS 260
>YGDH_SCHPO (O94574) Putative 2-hydroxyacid dehydrogenase C1773.17c (EC| 1.-.-.-) Length = 340 Score = 61.6 bits (148), Expect = 9e-10 Identities = 32/100 (32%), Positives = 54/100 (54%) Frame = +3 Query: 30 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 209 S +E+L +DVIS++ L T+ LI+ + MK ++N +RG +I+E A ++ +K+ Sbjct: 207 SFDELLSSSDVISINCPLTPATHDLISTKEFEKMKDGVYIINTARGAIINEDAFIKAIKS 266 Query: 210 NPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWT 329 + R GLDVF +EP E + PH + +T Sbjct: 267 GKVARAGLDVFLNEPTPNKFWLECDKVTIQPHCGVYTNFT 306
>SERA_SHIFL (P0A9T3) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 409 Score = 61.6 bits (148), Expect = 9e-10 Identities = 33/109 (30%), Positives = 63/109 (57%), Gaps = 6/109 (5%) Frame = +3 Query: 33 MEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN 212 + ++L +DV+SLH + +T +++ + +++MK ++L+NASRG V+D AL + L + Sbjct: 196 LSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASK 255 Query: 213 PMFRVGLDVFEDE------PYMKPGLAEMKNAVVVPHIASASKWTREGM 341 + +DVF E P+ P L E N ++ PHI +++ +E + Sbjct: 256 HLAGAAIDVFPTEPATNSDPFTSP-LCEFDNVLLTPHIGGSTQEAQENI 303
>SERA_ECOLI (P0A9T0) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 409 Score = 61.6 bits (148), Expect = 9e-10 Identities = 33/109 (30%), Positives = 63/109 (57%), Gaps = 6/109 (5%) Frame = +3 Query: 33 MEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN 212 + ++L +DV+SLH + +T +++ + +++MK ++L+NASRG V+D AL + L + Sbjct: 196 LSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASK 255 Query: 213 PMFRVGLDVFEDE------PYMKPGLAEMKNAVVVPHIASASKWTREGM 341 + +DVF E P+ P L E N ++ PHI +++ +E + Sbjct: 256 HLAGAAIDVFPTEPATNSDPFTSP-LCEFDNVLLTPHIGGSTQEAQENI 303
>SERA_ECOL6 (P0A9T1) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 409 Score = 61.6 bits (148), Expect = 9e-10 Identities = 33/109 (30%), Positives = 63/109 (57%), Gaps = 6/109 (5%) Frame = +3 Query: 33 MEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN 212 + ++L +DV+SLH + +T +++ + +++MK ++L+NASRG V+D AL + L + Sbjct: 196 LSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASK 255 Query: 213 PMFRVGLDVFEDE------PYMKPGLAEMKNAVVVPHIASASKWTREGM 341 + +DVF E P+ P L E N ++ PHI +++ +E + Sbjct: 256 HLAGAAIDVFPTEPATNSDPFTSP-LCEFDNVLLTPHIGGSTQEAQENI 303
>SERA_ECO57 (P0A9T2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 409 Score = 61.6 bits (148), Expect = 9e-10 Identities = 33/109 (30%), Positives = 63/109 (57%), Gaps = 6/109 (5%) Frame = +3 Query: 33 MEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN 212 + ++L +DV+SLH + +T +++ + +++MK ++L+NASRG V+D AL + L + Sbjct: 196 LSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASK 255 Query: 213 PMFRVGLDVFEDE------PYMKPGLAEMKNAVVVPHIASASKWTREGM 341 + +DVF E P+ P L E N ++ PHI +++ +E + Sbjct: 256 HLAGAAIDVFPTEPATNSDPFTSP-LCEFDNVLLTPHIGGSTQEAQENI 303
>SERA_YEAST (P40054) D-3-phosphoglycerate dehydrogenase 1 (EC 1.1.1.95) (3-PGDH| 1) Length = 469 Score = 61.6 bits (148), Expect = 9e-10 Identities = 35/118 (29%), Positives = 64/118 (54%), Gaps = 14/118 (11%) Frame = +3 Query: 12 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 191 T ++ S+++E+L ++D ++LH T +++ + A MK A ++NASRG V+D +L Sbjct: 237 TARQVSTLDELLNKSDFVTLHVPATPETEKMLSAPQFAAMKDGAYVINASRGTVVDIPSL 296 Query: 192 VEHLKANPMFRVGLDVFEDEPYMKPG--------------LAEMKNAVVVPHIASASK 323 ++ +KAN + LDV+ EP K G L + N ++ PHI +++ Sbjct: 297 IQAVKANKIAGAALDVYPHEP-AKNGEGSFNDELNSWTSELVSLPNIILTPHIGGSTE 353
>SER33_YEAST (P40510) D-3-phosphoglycerate dehydrogenase 2 (EC 1.1.1.95) (3-PGDH| 2) Length = 469 Score = 61.6 bits (148), Expect = 9e-10 Identities = 35/118 (29%), Positives = 64/118 (54%), Gaps = 14/118 (11%) Frame = +3 Query: 12 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 191 T ++ S+++E+L ++D ++LH T +++ + A MK A ++NASRG V+D +L Sbjct: 237 TARQVSTLDELLNKSDFVTLHVPATPETEKMLSAPQFAAMKDGAYVINASRGTVVDIPSL 296 Query: 192 VEHLKANPMFRVGLDVFEDEPYMKPG--------------LAEMKNAVVVPHIASASK 323 ++ +KAN + LDV+ EP K G L + N ++ PHI +++ Sbjct: 297 IQAVKANKIAGAALDVYPHEP-AKNGEGSFNDELNSWTSELVSLPNIILTPHIGGSTE 353
>SERA_RAT (O08651) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 61.2 bits (147), Expect = 1e-09 Identities = 32/97 (32%), Positives = 53/97 (54%) Frame = +3 Query: 33 MEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN 212 +EE+ D I++H L +T L+N A KK +VN +RG ++DE AL+ L++ Sbjct: 192 LEEIWPLCDFITVHTPLLPSTTGLLNDSTFAQCKKGVRVVNCARGGIVDEGALLRALQSG 251 Query: 213 PMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASK 323 LDVF +EP L + +N + PH+ +++K Sbjct: 252 QCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTK 288
>SERA_MOUSE (Q61753) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| (A10) Length = 532 Score = 61.2 bits (147), Expect = 1e-09 Identities = 32/97 (32%), Positives = 53/97 (54%) Frame = +3 Query: 33 MEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN 212 +EE+ D I++H L +T L+N A KK +VN +RG ++DE AL+ L++ Sbjct: 192 LEEIWPLCDFITVHTPLLPSTTGLLNDSTFAQCKKGVRVVNCARGGIVDEGALLRALQSG 251 Query: 213 PMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASK 323 LDVF +EP L + +N + PH+ +++K Sbjct: 252 QCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTK 288
>SERA_MACFA (Q60HD7) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 61.2 bits (147), Expect = 1e-09 Identities = 32/97 (32%), Positives = 53/97 (54%) Frame = +3 Query: 33 MEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN 212 +EE+ D I++H L +T L+N A KK +VN +RG ++DE AL+ L++ Sbjct: 192 LEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSG 251 Query: 213 PMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASK 323 LDVF +EP L + +N + PH+ +++K Sbjct: 252 QCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTK 288
>SERA_HUMAN (O43175) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 61.2 bits (147), Expect = 1e-09 Identities = 32/97 (32%), Positives = 53/97 (54%) Frame = +3 Query: 33 MEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN 212 +EE+ D I++H L +T L+N A KK +VN +RG ++DE AL+ L++ Sbjct: 192 LEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSG 251 Query: 213 PMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASK 323 LDVF +EP L + +N + PH+ +++K Sbjct: 252 QCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTK 288
>SERA_PONPY (Q5R7M2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 60.8 bits (146), Expect = 2e-09 Identities = 32/97 (32%), Positives = 53/97 (54%) Frame = +3 Query: 33 MEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN 212 +EE+ D I++H L +T L+N A KK +VN +RG ++DE AL+ L++ Sbjct: 192 LEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSG 251 Query: 213 PMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASK 323 LDVF +EP L + +N + PH+ +++K Sbjct: 252 QCAGAALDVFTEEPPRGRALVDHENVISCPHLGASTK 288
>DHGY_HYPME (P36234) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-dependent| hydroxypyruvate reductase) (HPR) (GDH) (Hydroxypyruvate dehydrogenase) (Glyoxylate reductase) Length = 321 Score = 60.8 bits (146), Expect = 2e-09 Identities = 32/105 (30%), Positives = 54/105 (51%) Frame = +3 Query: 30 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 209 S++ +L + SL+ T + N + + + A++VN +RG ++D +V L+A Sbjct: 196 SLDSLLSVSQFFSLNAPSTPETRYFFNKATIKSLPQGAIVVNTARGDLVDNELVVAALEA 255 Query: 210 NPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 344 + G DVF EP + G ++ N + PHI SA+ RE MA Sbjct: 256 GRLAYAGFDVFAGEPNINEGYYDLPNTFLFPHIGSAATQAREDMA 300
>VANH_ENTFC (Q05709) D-specific alpha-keto acid dehydrogenase (EC 1.1.1.-)| (Vancomycin resistance protein vanH) Length = 322 Score = 60.5 bits (145), Expect = 2e-09 Identities = 34/106 (32%), Positives = 57/106 (53%), Gaps = 14/106 (13%) Frame = +3 Query: 36 EEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANP 215 +E+L+ +D+++LH L+ T+++I+ E++ MK+ A L+N RGP++D LV+ L+ Sbjct: 189 DELLQNSDIVTLHVPLNTDTHYIISHEQIQRMKQGAFLINTGRGPLVDTYELVKALENGK 248 Query: 216 MFRVGLDVFEDEP-------YMKP-------GLAEMKNAVVVPHIA 311 + LDV E E KP L M N ++ PH A Sbjct: 249 LGGAALDVLEGEEEFFYSDCTQKPIDNQFLLKLQRMPNVIITPHTA 294
>PDXB_ECOL6 (Q8FFH2) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 60.5 bits (145), Expect = 2e-09 Identities = 42/124 (33%), Positives = 64/124 (51%), Gaps = 6/124 (4%) Frame = +3 Query: 30 SMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 197 S++E+++ AD+++ H L K T HL + + + +K A+L+NA RG V+D AL+ Sbjct: 160 SLDELVQHADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALLT 219 Query: 198 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA--TLAALNVLV 371 L V LDV+E EP + L + K + PHIA +T EG A T Sbjct: 220 CLNEGQKLSVVLDVWEGEPELNVELLK-KVDIGTPHIAG---YTLEGKARGTTQVFEAYS 275 Query: 372 SFLG 383 F+G Sbjct: 276 KFIG 279
>SERA_BOVIN (Q5EAD2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 60.1 bits (144), Expect = 3e-09 Identities = 31/97 (31%), Positives = 52/97 (53%) Frame = +3 Query: 33 MEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN 212 +E++ D I++H L +T L+N A KK +VN +RG ++DE AL+ L++ Sbjct: 192 LEQIWPLCDFITVHTPLLPSTTGLLNDSTFAQCKKGVCVVNCARGGIVDEGALLRALQSG 251 Query: 213 PMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASK 323 LDVF +EP L +N + PH+ +++K Sbjct: 252 QCAGAALDVFTEEPPRDRALVNHENVISCPHLGASTK 288
>LDHD_ECOLI (P52643) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH)| (Fermentative lactate dehydrogenase) Length = 329 Score = 60.1 bits (144), Expect = 3e-09 Identities = 30/67 (44%), Positives = 41/67 (61%) Frame = +3 Query: 51 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 230 E+DVISLH L YHL+N MK ++VN SRG +ID A +E LK + +G Sbjct: 197 ESDVISLHCPLTPENYHLLNEAAFEQMKNGVMIVNTSRGALIDSQAAIEALKNQKIGSLG 256 Query: 231 LDVFEDE 251 +DV+E+E Sbjct: 257 MDVYENE 263
>PDXB_SHIFL (Q83QR1) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 59.7 bits (143), Expect = 4e-09 Identities = 42/124 (33%), Positives = 63/124 (50%), Gaps = 6/124 (4%) Frame = +3 Query: 30 SMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 197 S++E+++ AD+++ H L K T HL + + + +K A+L+NA RG V+D AL+ Sbjct: 160 SLDELVQRADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALLT 219 Query: 198 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA--TLAALNVLV 371 L V LDV+E EP + L K + PHIA +T EG A T Sbjct: 220 CLNEGQKLSVVLDVWEGEPELNVELL-TKVDIGTPHIAG---YTLEGKARGTTQVFEAYS 275 Query: 372 SFLG 383 F+G Sbjct: 276 KFIG 279
>PDXB_ERWCT (Q6D2N5) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 59.7 bits (143), Expect = 4e-09 Identities = 42/125 (33%), Positives = 64/125 (51%), Gaps = 6/125 (4%) Frame = +3 Query: 30 SMEEVLREADVISLHPVL----DKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 197 S+E ++R+AD+++LH L T+HL++ L +L+NA RGPV+D AL+E Sbjct: 160 SLETLVRDADILTLHTPLYLDGPYRTHHLVDATVLNAFADGRILINACRGPVVDNAALLE 219 Query: 198 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA--TLAALNVLV 371 L+ V LDV+E EP + L + + HIA +T EG A T Sbjct: 220 ALQQGKKLSVILDVWEPEPGLSTDLLARVD-IGTAHIAG---YTLEGKARGTTQVFEAWS 275 Query: 372 SFLGS 386 F+G+ Sbjct: 276 EFIGT 280
>PDXB_ECO57 (Q8XCR0) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 59.7 bits (143), Expect = 4e-09 Identities = 42/124 (33%), Positives = 63/124 (50%), Gaps = 6/124 (4%) Frame = +3 Query: 30 SMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 197 S++E+++ AD+++ H L K T HL + + + +K A+L+NA RG V+D AL+ Sbjct: 160 SLDELVQRADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALLT 219 Query: 198 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA--TLAALNVLV 371 L V LDV+E EP + L K + PHIA +T EG A T Sbjct: 220 CLNEGQKLSVVLDVWEGEPELNVELL-TKVDIGTPHIAG---YTLEGKARGTTQVFEAYS 275 Query: 372 SFLG 383 F+G Sbjct: 276 KFIG 279
>VANH_ENTFA (Q47748) D-specific alpha-keto acid dehydrogenase (EC 1.1.1.-)| (Vancomycin B-type resistance protein vanHB) Length = 323 Score = 59.7 bits (143), Expect = 4e-09 Identities = 34/108 (31%), Positives = 55/108 (50%), Gaps = 15/108 (13%) Frame = +3 Query: 33 MEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN 212 ++E+L+ +D+++LH L T HLI ++ MK+ A L+N RG ++D +LVE L + Sbjct: 189 LDELLKNSDIVTLHVPLCADTRHLIGQRQIGEMKQGAFLINTGRGALVDTGSLVEALGSG 248 Query: 213 PMFRVGLDVFE---------------DEPYMKPGLAEMKNAVVVPHIA 311 + LDV E D P++ L M N ++ PH A Sbjct: 249 KLGGAALDVLEGEDQFVYTDCSQKVLDHPFLSQ-LLRMPNVIITPHTA 295
>DHD2_LACPA (P17584) D-2-hydroxyisocaproate dehydrogenase (EC 1.1.1.-)| (D-HICDH) Length = 333 Score = 59.3 bits (142), Expect = 5e-09 Identities = 42/132 (31%), Positives = 70/132 (53%), Gaps = 15/132 (11%) Frame = +3 Query: 30 SMEEVLREADVISLH-PVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLK 206 S+E++ +++DVI LH P +++ T H+IN +MK A+++N +R +ID A++ +LK Sbjct: 190 SLEDLFKQSDVIDLHVPGIEQNT-HIINEAAFNLMKPGAIVINTARPNLIDTQAMLSNLK 248 Query: 207 ANPMFRVGLDVFEDEPYMKPGLAE--------------MKNAVVVPHIASASKWTREGMA 344 + + VG+D +E E LA+ M N V+ PHIA ++ M Sbjct: 249 SGKLAGVGIDTYEYETEDLLNLAKHGSFKDPLWDELLGMPNVVLSPHIAYYTETAVHNMV 308 Query: 345 TLAALNVLVSFL 380 +L LV FL Sbjct: 309 YF-SLQHLVDFL 319
>LDHD_STAES (Q8CN22) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 58.9 bits (141), Expect = 6e-09 Identities = 35/109 (32%), Positives = 58/109 (53%), Gaps = 15/109 (13%) Frame = +3 Query: 30 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 209 ++E+ +++AD+ISLH +K ++HL + +KK AVLVNA+RG VI+ L+E + Sbjct: 191 TVEDAIKDADIISLHVPANKDSFHLFDNNMFKNVKKGAVLVNAARGAVINTPDLIEAVNN 250 Query: 210 NPMFRVGLDVFE---------------DEPYMKPGLAEMKNAVVVPHIA 311 + +D +E D+P + L +N +V PHIA Sbjct: 251 GTLSGAAIDTYENEANYFTFDCSNQTIDDPILL-DLIRNENILVTPHIA 298
>LDHD_STAEQ (Q5HLA0) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 58.9 bits (141), Expect = 6e-09 Identities = 35/109 (32%), Positives = 58/109 (53%), Gaps = 15/109 (13%) Frame = +3 Query: 30 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 209 ++E+ +++AD+ISLH +K ++HL + +KK AVLVNA+RG VI+ L+E + Sbjct: 191 TVEDAIKDADIISLHVPANKDSFHLFDNNMFKNVKKGAVLVNAARGAVINTPDLIEAVNN 250 Query: 210 NPMFRVGLDVFE---------------DEPYMKPGLAEMKNAVVVPHIA 311 + +D +E D+P + L +N +V PHIA Sbjct: 251 GTLSGAAIDTYENEANYFTFDCSNQTIDDPILL-DLIRNENILVTPHIA 298
>LDHD_STAAR (Q6GDS2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 58.9 bits (141), Expect = 6e-09 Identities = 34/108 (31%), Positives = 56/108 (51%), Gaps = 14/108 (12%) Frame = +3 Query: 30 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 209 S++E +++AD+ISLH +K +YHL + +KK A+LVNA+RG VI+ L++ + Sbjct: 191 SVKEAIKDADIISLHVPANKESYHLFDKTMFDHVKKGAILVNAARGAVINTPDLIDAVND 250 Query: 210 NPMFRVGLDVFEDEPYMKPG--------------LAEMKNAVVVPHIA 311 + +D +E+E L E + +V PHIA Sbjct: 251 GTLLGAAIDTYENEAAYFTNDWTNKDIDDKTLLELIEHERILVTPHIA 298
>PDXB_COXBU (Q83AR8) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 366 Score = 58.5 bits (140), Expect = 8e-09 Identities = 42/97 (43%), Positives = 55/97 (56%), Gaps = 4/97 (4%) Frame = +3 Query: 45 LREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN 212 L D++ LH L KT TYHLI+ L M+K +VL+NA RG VID AL L+ + Sbjct: 165 LANVDLVCLHTPLVKTGNFPTYHLIDNRFLKMLKPGSVLLNAGRGAVIDNNAL---LQCD 221 Query: 213 PMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASK 323 + LDV+E+EP + L E K + PHIA SK Sbjct: 222 HVITC-LDVWENEPTVNLQLLE-KTTIATPHIAGYSK 256
>LDHD_STAAW (Q8NUT2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 57.8 bits (138), Expect = 1e-08 Identities = 34/108 (31%), Positives = 55/108 (50%), Gaps = 14/108 (12%) Frame = +3 Query: 30 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 209 S++E +++AD+ISLH +K +YHL + +KK A+LVNA+RG VI+ L+ + Sbjct: 191 SVKEAIKDADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVND 250 Query: 210 NPMFRVGLDVFEDEPYMKPG--------------LAEMKNAVVVPHIA 311 + +D +E+E L E + +V PHIA Sbjct: 251 GTLLGAAIDTYENEAAYFTNDWTNKDIDDKTLLELIEHERILVTPHIA 298
>LDHD_STAAU (P72357) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 57.8 bits (138), Expect = 1e-08 Identities = 34/108 (31%), Positives = 55/108 (50%), Gaps = 14/108 (12%) Frame = +3 Query: 30 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 209 S++E +++AD+ISLH +K +YHL + +KK A+LVNA+RG VI+ L+ + Sbjct: 191 SVKEAIKDADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVND 250 Query: 210 NPMFRVGLDVFEDEPYMKPG--------------LAEMKNAVVVPHIA 311 + +D +E+E L E + +V PHIA Sbjct: 251 GTLLGAAIDTYENEAAYFTNDWTNKDIDDKTLLELIEHERILVTPHIA 298
>LDHD_STAAS (Q6G6F1) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 57.8 bits (138), Expect = 1e-08 Identities = 34/108 (31%), Positives = 55/108 (50%), Gaps = 14/108 (12%) Frame = +3 Query: 30 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 209 S++E +++AD+ISLH +K +YHL + +KK A+LVNA+RG VI+ L+ + Sbjct: 191 SVKEAIKDADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVND 250 Query: 210 NPMFRVGLDVFEDEPYMKPG--------------LAEMKNAVVVPHIA 311 + +D +E+E L E + +V PHIA Sbjct: 251 GTLLGAAIDTYENEAAYFTNDWTNKDIDDKTLLELIEHERILVTPHIA 298
>LDHD_STAAN (P99116) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 57.8 bits (138), Expect = 1e-08 Identities = 34/108 (31%), Positives = 55/108 (50%), Gaps = 14/108 (12%) Frame = +3 Query: 30 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 209 S++E +++AD+ISLH +K +YHL + +KK A+LVNA+RG VI+ L+ + Sbjct: 191 SVKEAIKDADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVND 250 Query: 210 NPMFRVGLDVFEDEPYMKPG--------------LAEMKNAVVVPHIA 311 + +D +E+E L E + +V PHIA Sbjct: 251 GTLLGAAIDTYENEAAYFTNDWTNKDIDDKTLLELIEHERILVTPHIA 298
>LDHD_STAAM (P63940) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 57.8 bits (138), Expect = 1e-08 Identities = 34/108 (31%), Positives = 55/108 (50%), Gaps = 14/108 (12%) Frame = +3 Query: 30 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 209 S++E +++AD+ISLH +K +YHL + +KK A+LVNA+RG VI+ L+ + Sbjct: 191 SVKEAIKDADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVND 250 Query: 210 NPMFRVGLDVFEDEPYMKPG--------------LAEMKNAVVVPHIA 311 + +D +E+E L E + +V PHIA Sbjct: 251 GTLLGAAIDTYENEAAYFTNDWTNKDIDDKTLLELIEHERILVTPHIA 298
>LDHD_STAAC (Q5HD29) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 57.8 bits (138), Expect = 1e-08 Identities = 34/108 (31%), Positives = 55/108 (50%), Gaps = 14/108 (12%) Frame = +3 Query: 30 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 209 S++E +++AD+ISLH +K +YHL + +KK A+LVNA+RG VI+ L+ + Sbjct: 191 SVKEAIKDADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVND 250 Query: 210 NPMFRVGLDVFEDEPYMKPG--------------LAEMKNAVVVPHIA 311 + +D +E+E L E + +V PHIA Sbjct: 251 GTLLGAAIDTYENEAAYFTNDWTNKDIDDKTLLELIEHERILVTPHIA 298
>PDXB_ECOLI (P05459) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 57.4 bits (137), Expect = 2e-08 Identities = 41/124 (33%), Positives = 63/124 (50%), Gaps = 6/124 (4%) Frame = +3 Query: 30 SMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 197 S++E+++ AD+++ H L K T HL + + + +K A+L+NA RG V+D AL+ Sbjct: 160 SLDELVQRADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALLT 219 Query: 198 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA--TLAALNVLV 371 L V LDV+E EP + L + K + HIA +T EG A T Sbjct: 220 CLNEGQKLSVVLDVWEGEPELNVELLK-KVDIGTSHIAG---YTLEGKARGTTQVFEAYS 275 Query: 372 SFLG 383 F+G Sbjct: 276 KFIG 279
>LDHD_LACHE (P30901) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 336 Score = 57.4 bits (137), Expect = 2e-08 Identities = 28/74 (37%), Positives = 46/74 (62%) Frame = +3 Query: 30 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 209 S++++ ++ADVISLH H+IN + +A MK V+VN SRG ++D A++ L + Sbjct: 191 SLDDLYKQADVISLHVPDVPANVHMINDKSIAEMKDGVVIVNCSRGRLVDTDAVIRGLDS 250 Query: 210 NPMFRVGLDVFEDE 251 +F +D +EDE Sbjct: 251 GKIFGFVMDTYEDE 264
>DDH_HAEIN (P44501) 2-hydroxyacid dehydrogenase homolog (EC 1.1.1.-)| Length = 331 Score = 57.4 bits (137), Expect = 2e-08 Identities = 28/73 (38%), Positives = 45/73 (61%) Frame = +3 Query: 33 MEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN 212 ++E+ ++ VI+LH YHL+N E A MK ++VN SRG +ID A ++ LK Sbjct: 191 LDELYAKSHVITLHCPATPENYHLLNCEAFAKMKDGVMIVNTSRGSLIDTQAAIDALKQR 250 Query: 213 PMFRVGLDVFEDE 251 + +G+DV+E+E Sbjct: 251 KIGALGMDVYENE 263
>PDXB_PHOPR (Q6LNU2) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 391 Score = 56.6 bits (135), Expect = 3e-08 Identities = 37/103 (35%), Positives = 57/103 (55%), Gaps = 9/103 (8%) Frame = +3 Query: 30 SMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 197 S+E + + DVI++H + K T+HLIN + ++ +A+L+NA+RGPV D AL + Sbjct: 161 SLEAIKAQCDVITVHTPITKDGEYPTHHLINEAFIDALQPDAILINAARGPVTDNQALKK 220 Query: 198 HLKAN-----PMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIA 311 L+ + LDVFE EP++ L + A PHIA Sbjct: 221 ALQLSQSGLGKKLTAVLDVFEFEPHVDLELLPLL-AFATPHIA 262
>PDXB_SHEVI (Q56733) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| (Fragment) Length = 274 Score = 56.2 bits (134), Expect = 4e-08 Identities = 37/101 (36%), Positives = 55/101 (54%), Gaps = 4/101 (3%) Frame = +3 Query: 30 SMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 197 S++E++ DVISLH + KT T++L + RL +K L+N RG VID AL++ Sbjct: 47 SLDELIARCDVISLHVPIIKTGEHKTWYLFDETRLNSLKPGTWLLNCCRGEVIDNRALIK 106 Query: 198 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 320 + P ++ LDV+E EP L + + PHIA S Sbjct: 107 VKQQRPDIKLVLDVWEGEPNPMHELIPLVE-LATPHIAGYS 146
>LDHD_LEUMC (P51011) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 331 Score = 56.2 bits (134), Expect = 4e-08 Identities = 34/108 (31%), Positives = 60/108 (55%), Gaps = 14/108 (12%) Frame = +3 Query: 30 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 209 +++E+ +AD ISL+ +HLIN + +A MK V++NA+RG ++D A+++ L + Sbjct: 191 TLDELYAQADAISLYVPGVPENHHLINADAIAKMKDGVVIMNAARGNLMDIDAIIDGLNS 250 Query: 210 NPMFRVGLDVFEDEP--YMKPGLAE------------MKNAVVVPHIA 311 + G+DV+E+E MK GL + +N ++ PH A Sbjct: 251 GKISDFGMDVYENEVACSMKIGLVKNSPDAKIADLIARENVMITPHTA 298
>PDXB_BACTN (Q8A2E4) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 348 Score = 55.8 bits (133), Expect = 5e-08 Identities = 35/102 (34%), Positives = 56/102 (54%), Gaps = 4/102 (3%) Frame = +3 Query: 27 SSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALV 194 +S+E++ E D+I+ H L K TYHL + ++++ V++N SRG VI+ AL+ Sbjct: 160 TSLEKIAEECDIITFHVPLYKEGKYKTYHLADGNFFRSLQRKPVVINTSRGEVIETNALL 219 Query: 195 EHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 320 E + + +DV+E EP + L E K + PHIA S Sbjct: 220 EAINNGIISDAVIDVWEHEPEINRELLE-KVLIGTPHIAGYS 260
>PDXB_SHESP (Q56731) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| (Fragment) Length = 274 Score = 55.5 bits (132), Expect = 7e-08 Identities = 37/101 (36%), Positives = 55/101 (54%), Gaps = 4/101 (3%) Frame = +3 Query: 30 SMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 197 S++E++ DVISLH + KT T++L + RL +K+ L+N RG VID AL++ Sbjct: 47 SLDELIACCDVISLHVPITKTGEHKTWYLFDEARLNSLKQGTWLLNCCRGEVIDNQALIK 106 Query: 198 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 320 P ++ LDV+E EP L + + PHIA S Sbjct: 107 VKLERPDIKLVLDVWEGEPNPMHELIPLVE-LATPHIAGYS 146
>LDHD_STRP1 (Q99ZM2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 54.3 bits (129), Expect = 1e-07 Identities = 29/78 (37%), Positives = 46/78 (58%), Gaps = 1/78 (1%) Frame = +3 Query: 30 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 209 S+EE +++AD++SLH HL N + KK A+L+N +RG VI+ L++ L A Sbjct: 191 SVEEAIKDADLVSLHMPPTAENTHLFNSDLFKSFKKGAILMNMARGAVIETQDLLDALDA 250 Query: 210 NPMFRVGLDVFEDE-PYM 260 + G+D +E E PY+ Sbjct: 251 GLLSGAGIDTYEFEGPYI 268
>LDHD_PEDAC (Q59642) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 331 Score = 52.8 bits (125), Expect = 4e-07 Identities = 32/125 (25%), Positives = 62/125 (49%), Gaps = 14/125 (11%) Frame = +3 Query: 30 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 209 ++EE+ ++A+VI+LH K YH+++ + M+ ++N +RG ++D AL++ L + Sbjct: 190 TLEELYQQANVITLHVPALKDNYHMLDEKAFGQMQDGTFILNFARGTLVDTPALLKALDS 249 Query: 210 NPMFRVGLDVFE-----------DEPYMKP---GLAEMKNAVVVPHIASASKWTREGMAT 347 + LD +E D+P P L +N ++ PH A ++ + M Sbjct: 250 GKVAGAALDTYENEVGIFDVDHGDQPIDDPVFNDLMSRRNVMITPHAAFYTRPAVKNMVQ 309 Query: 348 LAALN 362 +A N Sbjct: 310 IALDN 314
>LDHD_STRA5 (Q8E0N5) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 52.0 bits (123), Expect = 7e-07 Identities = 28/79 (35%), Positives = 45/79 (56%), Gaps = 1/79 (1%) Frame = +3 Query: 27 SSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLK 206 +S+EE + EAD++SLH HL N + KK A+L+N +RG +++ L+E L Sbjct: 190 NSVEEAVEEADLVSLHMPPTAENTHLFNLDMFKQFKKGAILMNMARGALVETKDLLEALD 249 Query: 207 ANPMFRVGLDVFEDE-PYM 260 + G+D +E E PY+ Sbjct: 250 QGLLEGAGIDTYEFEGPYI 268
>LDHD_LACPL (Q88VJ2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH)| Length = 332 Score = 52.0 bits (123), Expect = 7e-07 Identities = 25/74 (33%), Positives = 44/74 (59%) Frame = +3 Query: 30 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 209 +++E+ +ADVI+LH K YH++N + + MK A ++N +RG +ID L++ L + Sbjct: 191 TLDELYAQADVITLHVPALKDNYHMLNADAFSKMKDGAYILNFARGTLIDSEDLIKALDS 250 Query: 210 NPMFRVGLDVFEDE 251 + LD +E E Sbjct: 251 GKVAGAALDTYEYE 264
>PDXB_BLOFL (Q7VRU9) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 372 Score = 51.6 bits (122), Expect = 1e-06 Identities = 33/108 (30%), Positives = 59/108 (54%), Gaps = 4/108 (3%) Frame = +3 Query: 9 VTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVI 176 ++WK S++ ++ ++D+++LH L T T+H+IN + L + ++L+N SRG V+ Sbjct: 157 MSWK---SLDILVSKSDILTLHVPLTYTGAYPTWHMINKDILDALPSNSILINTSRGAVV 213 Query: 177 DEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 320 + L+ L+ V LDV+E EP + L + + HIA S Sbjct: 214 NNDDLLAILRCGKKINVILDVWESEPKLSLPLLSYVD-IGTAHIAGYS 260
>FDH_NEUCR (Q07103) Formate dehydrogenase (EC 1.2.1.2) (NAD-dependent formate| dehydrogenase) (FDH) Length = 375 Score = 51.2 bits (121), Expect = 1e-06 Identities = 33/107 (30%), Positives = 59/107 (55%), Gaps = 6/107 (5%) Frame = +3 Query: 18 KRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 197 +R + +EE+L + DV++++ L + T L N E ++ MKK + LVN +RG ++ + + E Sbjct: 211 RRVADLEEMLAQCDVVTINCPLHEKTQGLFNKELISKMKKGSWLVNTARGAIVVKEDVAE 270 Query: 198 HLKANPMFRVGLDVFEDEPYMKP-GLAEMKNA-----VVVPHIASAS 320 LK+ + G DV+ +P + L KN +VPH++ S Sbjct: 271 ALKSGHLRGYGGDVWFPQPAPQDHPLRYAKNPFGGGNAMVPHMSGTS 317
>FDH1_ORYSA (Q9SXP2) Formate dehydrogenase 1, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase 1) (FDH 1) Length = 376 Score = 50.8 bits (120), Expect = 2e-06 Identities = 30/102 (29%), Positives = 53/102 (51%), Gaps = 1/102 (0%) Frame = +3 Query: 18 KRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 197 K ++ +L + DVI ++ L + T + N ER+A MKK ++VN +RG ++D A+ + Sbjct: 234 KYEEDLDAMLPKCDVIVINTPLTEKTRGMFNKERIAKMKKGVIIVNNARGAIMDTQAVAD 293 Query: 198 HLKANPMFRVGLDVFEDEPYMKP-GLAEMKNAVVVPHIASAS 320 + + G DV+ +P K M N + PHI+ + Sbjct: 294 ACSSGQVAGYGGDVWFPQPAPKDHPWRYMPNHAMTPHISGTT 335
>LDHD_STRA3 (Q8E6A9) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 50.4 bits (119), Expect = 2e-06 Identities = 27/79 (34%), Positives = 45/79 (56%), Gaps = 1/79 (1%) Frame = +3 Query: 27 SSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLK 206 +S+EE + +AD++SLH HL N + KK A+L+N +RG +++ L+E L Sbjct: 190 NSVEEAVEKADLVSLHMPPTAENTHLFNLDMFKQFKKGAILMNMARGALVETKDLLEALD 249 Query: 207 ANPMFRVGLDVFEDE-PYM 260 + G+D +E E PY+ Sbjct: 250 QGLLEGAGIDTYEFEGPYI 268
>YP113_YEAST (Q02961) Putative 2-hydroxyacid dehydrogenase YPL113C (EC 1.-.-.-)| Length = 396 Score = 49.3 bits (116), Expect = 5e-06 Identities = 35/104 (33%), Positives = 51/104 (49%), Gaps = 1/104 (0%) Frame = +3 Query: 6 PVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEV 185 P TWK A D+I L +T ++IN + LA K +VN RG IDE Sbjct: 271 PNTWKNA----------DLIILALPSTASTNNIINRKSLAWCKDGVRIVNVGRGTCIDED 320 Query: 186 ALVEHLKANPMFRVGLDVFE-DEPYMKPGLAEMKNAVVVPHIAS 314 L++ L++ + GLDVF+ +E +K L + +PHI S Sbjct: 321 VLLDALESGKVASCGLDVFKNEETRVKQELLRRWDVTALPHIGS 364
>FDH_HORVU (Q9ZRI8) Formate dehydrogenase, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase) (FDH) Length = 377 Score = 48.5 bits (114), Expect = 8e-06 Identities = 28/102 (27%), Positives = 53/102 (51%), Gaps = 1/102 (0%) Frame = +3 Query: 18 KRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 197 K ++ +L + DV+ ++ L + T + N E++A MKK ++VN +RG ++D A+ + Sbjct: 235 KFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVAD 294 Query: 198 HLKANPMFRVGLDVFEDEPYMKP-GLAEMKNAVVVPHIASAS 320 + + G DV+ +P K M N + PHI+ + Sbjct: 295 ACSSGHIAGYGGDVWFPQPAPKDHPWRYMPNHAMTPHISGTT 336
>LDHD_LACPE (P26298) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 332 Score = 48.5 bits (114), Expect = 8e-06 Identities = 24/74 (32%), Positives = 43/74 (58%) Frame = +3 Query: 30 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 209 +++E+ +ADVI+LH K YH++N + + MK A ++N +RG +ID L++ L + Sbjct: 191 TLDELYAQADVITLHVPALKDNYHMLNADAFSKMKDGAYILNFARGTLIDSEDLIKALDS 250 Query: 210 NPMFRVGLDVFEDE 251 + L +E E Sbjct: 251 GKVAGAALVTYEYE 264
>YGT5_YEAST (P53100) Putative 2-hydroxyacid dehydrogenase YGL185C (EC 1.-.-.-)| Length = 379 Score = 46.6 bits (109), Expect = 3e-05 Identities = 30/93 (32%), Positives = 44/93 (47%), Gaps = 1/93 (1%) Frame = +3 Query: 93 TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGL 272 T HLIN + L +LVN RG ++D A+ + L + +GLDVF EP + + Sbjct: 270 TEHLINRKFLEHCNPGLILVNLGRGKILDLRAVSDALVTGRINHLGLDVFNKEPEIDEKI 329 Query: 273 AEMKNAV-VVPHIASASKWTREGMATLAALNVL 368 + PH+ SA+K E LA +L Sbjct: 330 RSSDRLTSITPHLGSATKDVFEQSCELALTRIL 362
>FDH_SOLTU (Q07511) Formate dehydrogenase, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase) (FDH) Length = 381 Score = 46.6 bits (109), Expect = 3e-05 Identities = 26/102 (25%), Positives = 54/102 (52%), Gaps = 1/102 (0%) Frame = +3 Query: 18 KRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 197 K ++++L + D++ ++ L + T + + ER+A +KK ++VN +RG ++D A+V+ Sbjct: 239 KFEEDLDKMLSKCDIVVINTPLTEKTKGMFDKERIAKLKKGVLIVNNARGAIMDTQAVVD 298 Query: 198 HLKANPMFRVGLDVFEDEPYMKP-GLAEMKNAVVVPHIASAS 320 + + DV+ +P K M N + PHI+ + Sbjct: 299 ACNSGHIAGYSGDVWYPQPAPKDHPWRYMPNQAMTPHISGTT 340
>FDH2_ORYSA (Q67U69) Formate dehydrogenase 2, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase 2) (FDH 2) Length = 378 Score = 46.2 bits (108), Expect = 4e-05 Identities = 28/102 (27%), Positives = 51/102 (50%), Gaps = 1/102 (0%) Frame = +3 Query: 18 KRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 197 K ++ +L + DV+ ++ L + T + N ER+A MKK +VN +RG ++D A+ + Sbjct: 236 KYEEDLDAMLPKCDVVVINMPLTEKTRGMFNKERIAKMKKGVTIVNNARGAIMDTQAVAD 295 Query: 198 HLKANPMFRVGLDVFEDEPYMKP-GLAEMKNAVVVPHIASAS 320 + + G DV+ +P K M N + PH + + Sbjct: 296 ACASGHVAGYGGDVWFPQPAPKDHPWRYMPNHAMTPHCSGTT 337
>FDH_ARATH (Q9S7E4) Formate dehydrogenase, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase) (FDH) Length = 384 Score = 44.7 bits (104), Expect = 1e-04 Identities = 26/102 (25%), Positives = 53/102 (51%), Gaps = 1/102 (0%) Frame = +3 Query: 18 KRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 197 K + E+L + DVI ++ L + T + N E + +KK ++VN +RG +++ A+V+ Sbjct: 242 KFVEDLNEMLPKCDVIVINMPLTEKTRGMFNKELIGKLKKGVLIVNNARGAIMERQAVVD 301 Query: 198 HLKANPMFRVGLDVFEDEPYMKP-GLAEMKNAVVVPHIASAS 320 +++ + DV++ +P K M N + PH + + Sbjct: 302 AVESGHIGGYSGDVWDPQPAPKDHPWRYMPNQAMTPHTSGTT 343
>FDH_PSESR (P33160) Formate dehydrogenase (EC 1.2.1.2) (NAD-dependent formate| dehydrogenase) (FDH) Length = 400 Score = 44.7 bits (104), Expect = 1e-04 Identities = 26/85 (30%), Positives = 46/85 (54%) Frame = +3 Query: 9 VTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVA 188 +TW ++ E++ DV++L+ L T H+IN E L + K+ A +VN +RG + D A Sbjct: 235 LTWH--ATREDMYPVCDVVTLNCPLHPETEHMINDETLKLFKRGAYIVNTARGKLCDRDA 292 Query: 189 LVEHLKANPMFRVGLDVFEDEPYMK 263 + L++ + DV+ +P K Sbjct: 293 VARALESGRLAGYAGDVWFPQPAPK 317
>FDH2_YEAST (Q08987) Formate dehydrogenase 2 (EC 1.2.1.2) (NAD-dependent| formate dehydrogenase 2) Length = 376 Score = 44.7 bits (104), Expect = 1e-04 Identities = 23/82 (28%), Positives = 47/82 (57%) Frame = +3 Query: 18 KRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 197 +R +E+++ ++DV++++ L K + L N + ++ MK A LVN +RG + + E Sbjct: 224 QRVEKLEDMVAQSDVVTINCPLHKDSRGLFNKKLISHMKDGAYLVNTARGAICVAEDVAE 283 Query: 198 HLKANPMFRVGLDVFEDEPYMK 263 +K+ + G DV++ +P K Sbjct: 284 AVKSGKLAGYGGDVWDKQPAPK 305
>FDH1_YEAST (Q08911) Formate dehydrogenase 1 (EC 1.2.1.2) (NAD-dependent| formate dehydrogenase 1) Length = 376 Score = 44.7 bits (104), Expect = 1e-04 Identities = 23/82 (28%), Positives = 47/82 (57%) Frame = +3 Query: 18 KRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 197 +R +E+++ ++DV++++ L K + L N + ++ MK A LVN +RG + + E Sbjct: 224 QRVEKLEDMVAQSDVVTINCPLHKDSRGLFNKKLISHMKDGAYLVNTARGAICVAEDVAE 283 Query: 198 HLKANPMFRVGLDVFEDEPYMK 263 +K+ + G DV++ +P K Sbjct: 284 AVKSGKLAGYGGDVWDKQPAPK 305
>FDH_PICAN (P33677) Formate dehydrogenase (EC 1.2.1.2) (NAD-dependent formate| dehydrogenase) (FDH) Length = 361 Score = 39.7 bits (91), Expect = 0.004 Identities = 23/82 (28%), Positives = 44/82 (53%) Frame = +3 Query: 18 KRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 197 +R ++E++ +AD+++++ L + L+N E L KK A LVN +RG + + Sbjct: 209 RRVHDIKELVAQADIVTINCPLHAGSKGLVNAELLKHFKKGAWLVNTARGAICVAEDVAA 268 Query: 198 HLKANPMFRVGLDVFEDEPYMK 263 +K+ + G DV+ +P K Sbjct: 269 AVKSGQLRGYGGDVWFPQPAPK 290
>FDH_EMENI (Q03134) Probable formate dehydrogenase (EC 1.2.1.2) (NAD-dependent| formate dehydrogenase) (FDH) Length = 377 Score = 39.7 bits (91), Expect = 0.004 Identities = 27/99 (27%), Positives = 49/99 (49%), Gaps = 17/99 (17%) Frame = +3 Query: 18 KRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMK-----------------KEAV 146 +R S+EE++ + DV++++ L + T L N E ++ MK K + Sbjct: 206 RRVDSLEEMVSQCDVVTINCPLHEKTRGLFNKELISKMKPGKSALLYLIIPMLMYHKGSW 265 Query: 147 LVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMK 263 LVN +RG ++ + + E LK+ + G DV+ +P K Sbjct: 266 LVNTARGAIVVKEDVAEALKSGHLRGYGGDVWFPQPAPK 304
>YCDW_ECOLI (P75913) Putative 2-hydroxyacid dehydrogenase ycdW (EC 1.-.-.-)| Length = 325 Score = 32.3 bits (72), Expect = 0.61 Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 1/78 (1%) Frame = +3 Query: 93 TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPY-MKPG 269 T +IN + L + A L+N +RG + E L+ L + + LDVF EP + Sbjct: 217 TVGIINQQLLEKLPDGAYLLNLARGVHVVEDDLLAALDSGKVKGAMLDVFNREPLPPESP 276 Query: 270 LAEMKNAVVVPHIASASK 323 L + + PH+A+ ++ Sbjct: 277 LWQHPRVTITPHVAAITR 294
>FAT_DROME (P33450) Cadherin-related tumor suppressor precursor (Protein fat)| Length = 5147 Score = 30.0 bits (66), Expect = 3.0 Identities = 15/39 (38%), Positives = 23/39 (58%) Frame = +3 Query: 9 VTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLA 125 +T RASS+ + +DV P D TTY++ PER++ Sbjct: 2572 ITEPRASSVNLTISVSDVNDNIPKFDSTTYNVAVPERIS 2610
>NUOL_BUCAI (P57262) NADH-quinone oxidoreductase chain L (EC 1.6.99.5) (NADH| dehydrogenase I, chain L) (NDH-1, chain L) Length = 614 Score = 29.6 bits (65), Expect = 3.9 Identities = 13/50 (26%), Positives = 24/50 (48%) Frame = -1 Query: 211 LALRCSTSATSSITGPRLAFTSTASFFIIASRSGFIRWYVVLSSTGCRLI 62 ++ R S + I L T +F+++ + +G++RWYV G I Sbjct: 555 ISKRLSADPLNKIINYFLKVTQIFNFYLLKTSNGYVRWYVASMILGINFI 604
>WSC2_YEAST (P53832) Cell wall integrity and stress response component 2| precursor Length = 503 Score = 29.6 bits (65), Expect = 3.9 Identities = 28/102 (27%), Positives = 40/102 (39%) Frame = -1 Query: 442 TTTSAPNKHGLLD*LSHIIDPRKLTSTFRAASVAIPSRVHLDADAM*GTTTAFFISASPG 263 T+T K +H TST ++S S + + TT+ ++S Sbjct: 147 TSTKLDTKTSTSSSATHSSSSSSTTSTTTSSSETTTSSSSSSSSSSTSTTSTTSTTSSTT 206 Query: 262 FM*GSSSKTSRPTRNMGLALRCSTSATSSITGPRLAFTSTAS 137 S S TS T + ST ATSS T + TSTA+ Sbjct: 207 STSSSPSTTSSSTSASSSSETSSTQATSSSTTSTSSSTSTAT 248
>FIP1_PONPY (Q5RAA7) Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1)| Length = 588 Score = 29.3 bits (64), Expect = 5.1 Identities = 11/19 (57%), Positives = 14/19 (73%) Frame = +3 Query: 213 PMFRVGLDVFEDEPYMKPG 269 P+ V LD FED+P+ KPG Sbjct: 136 PLLEVDLDSFEDKPWRKPG 154
>FIP1_HUMAN (Q6UN15) Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1)| (Factor interacting with PAP) (hFip1) (Rearranged in hypereosinophilia) Length = 594 Score = 29.3 bits (64), Expect = 5.1 Identities = 11/19 (57%), Positives = 14/19 (73%) Frame = +3 Query: 213 PMFRVGLDVFEDEPYMKPG 269 P+ V LD FED+P+ KPG Sbjct: 151 PLLEVDLDSFEDKPWRKPG 169
>FIP1_RAT (Q5U317) Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1)| Length = 536 Score = 29.3 bits (64), Expect = 5.1 Identities = 11/19 (57%), Positives = 14/19 (73%) Frame = +3 Query: 213 PMFRVGLDVFEDEPYMKPG 269 P+ V LD FED+P+ KPG Sbjct: 150 PLLEVDLDSFEDKPWRKPG 168
>COBT_ECOLI (P36562) Nicotinate-nucleotide--dimethylbenzimidazole| phosphoribosyltransferase (EC 2.4.2.21) (NN:DBI PRT) (N(1)-alpha-phosphoribosyltransferase) Length = 359 Score = 29.3 bits (64), Expect = 5.1 Identities = 23/79 (29%), Positives = 31/79 (39%), Gaps = 2/79 (2%) Frame = +3 Query: 141 AVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPY--MKPGLAEMKNAVVVPHIAS 314 A L P I + HL A R+ L EPY M+ L E A + I Sbjct: 271 AALAACQMSPAIKPYLIPSHLSAEKGARIALSHLGLEPYLNMEMRLGEGSGAALAMPIIE 330 Query: 315 ASKWTREGMATLAALNVLV 371 A+ M LAA N+++ Sbjct: 331 AACAIYNNMGELAASNIVL 349
>FIP1_MOUSE (Q9D824) Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1)| Length = 581 Score = 29.3 bits (64), Expect = 5.1 Identities = 11/19 (57%), Positives = 14/19 (73%) Frame = +3 Query: 213 PMFRVGLDVFEDEPYMKPG 269 P+ V LD FED+P+ KPG Sbjct: 150 PLLEVDLDSFEDKPWRKPG 168
>CBID_SYNEL (Q8DKT8) Putative cobalt-precorrin-6A synthase [deacetylating] (EC| 2.1.1.-) Length = 367 Score = 29.3 bits (64), Expect = 5.1 Identities = 14/39 (35%), Positives = 20/39 (51%) Frame = -3 Query: 257 VRLILKNIEADTEHGVSLEVLHQCNLVDHRATARVHQHC 141 V LK +E H + + H + +D RATA +H HC Sbjct: 291 VEAALKFLERMVPHVLPEILSHIAHRIDQRATAYIHAHC 329
>NUP82_YEAST (P40368) Nucleoporin NUP82 (Nuclear pore protein NUP82)| Length = 713 Score = 29.3 bits (64), Expect = 5.1 Identities = 20/66 (30%), Positives = 31/66 (46%) Frame = -1 Query: 208 ALRCSTSATSSITGPRLAFTSTASFFIIASRSGFIRWYVVLSSTGCRLITSASLRTSSML 29 AL ++ S+ PR F+S I+ + IRWY VL+ + L S + +L Sbjct: 9 ALPIFQASLSASQSPRYIFSSQNGTRIVFIQDNIIRWYNVLTDS---LYHSLNFSRHLVL 65 Query: 28 EALFHV 11 + FHV Sbjct: 66 DDTFHV 71
>NADB_NEIMB (Q9K107) L-aspartate oxidase (EC 1.4.3.16) (LASPO) (Quinolinate| synthetase B) Length = 502 Score = 28.9 bits (63), Expect = 6.7 Identities = 17/54 (31%), Positives = 24/54 (44%) Frame = -3 Query: 299 HDDGILHLSQPWLHVRLILKNIEADTEHGVSLEVLHQCNLVDHRATARVHQHCL 138 H D L+ + R I I T+ VSL++ HQ R +H+HCL Sbjct: 266 HYDRRAELAPRDIVARAIAAEIAKQTQDFVSLDISHQPAAFVRRHFPSIHRHCL 319
>NADB_NEIMA (Q9JSX4) L-aspartate oxidase (EC 1.4.3.16) (LASPO) (Quinolinate| synthetase B) Length = 502 Score = 28.9 bits (63), Expect = 6.7 Identities = 17/54 (31%), Positives = 24/54 (44%) Frame = -3 Query: 299 HDDGILHLSQPWLHVRLILKNIEADTEHGVSLEVLHQCNLVDHRATARVHQHCL 138 H D L+ + R I I T+ VSL++ HQ R +H+HCL Sbjct: 266 HYDRRAELAPRDIVARAIAAEIAKQTQDFVSLDISHQPAAFVRRHFPSIHRHCL 319
>COBT_SHIFL (Q83R14) Nicotinate-nucleotide--dimethylbenzimidazole| phosphoribosyltransferase (EC 2.4.2.21) (NN:DBI PRT) (N(1)-alpha-phosphoribosyltransferase) Length = 359 Score = 28.9 bits (63), Expect = 6.7 Identities = 23/79 (29%), Positives = 30/79 (37%), Gaps = 2/79 (2%) Frame = +3 Query: 141 AVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPY--MKPGLAEMKNAVVVPHIAS 314 A L P I + HL A R+ L EPY M L E A + I Sbjct: 271 AALAACQMSPAIKPYLIPSHLSAEKGARIALSHLGLEPYLNMDMRLGEGSGAALAMSIIE 330 Query: 315 ASKWTREGMATLAALNVLV 371 A+ M LAA N+++ Sbjct: 331 AACAIYNNMGELAASNIVL 349
>COBT_ECOL6 (Q8FGA5) Nicotinate-nucleotide--dimethylbenzimidazole| phosphoribosyltransferase (EC 2.4.2.21) (NN:DBI PRT) (N(1)-alpha-phosphoribosyltransferase) Length = 359 Score = 28.9 bits (63), Expect = 6.7 Identities = 23/79 (29%), Positives = 30/79 (37%), Gaps = 2/79 (2%) Frame = +3 Query: 141 AVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPY--MKPGLAEMKNAVVVPHIAS 314 A L P I + HL A R+ L EPY M L E A + I Sbjct: 271 AALAACQMSPAIKPYLIPSHLSAEKGARIALSHLGLEPYLNMDMRLGEGSGAALAMSIIE 330 Query: 315 ASKWTREGMATLAALNVLV 371 A+ M LAA N+++ Sbjct: 331 AACAIYNNMGELAASNIVL 349
>SYA_THET8 (P74941) Alanyl-tRNA synthetase (EC 6.1.1.7) (Alanine--tRNA ligase)| (AlaRS) Length = 882 Score = 28.9 bits (63), Expect = 6.7 Identities = 26/81 (32%), Positives = 38/81 (46%), Gaps = 2/81 (2%) Frame = +3 Query: 15 WKRASSMEEVLREADVISLHPVLDKTTYH--LINPERLAMMKKEAVLVNASRGPVIDEVA 188 W+R ++ +E LR D+ ++ TY L N KKEA+L Sbjct: 61 WRRVTTCQECLRVGDIENVGRTSRHNTYFEMLGNFSFGDYFKKEAILWAWE--------F 112 Query: 189 LVEHLKANPMFRVGLDVFEDE 251 L EHLK +P R+ + VFED+ Sbjct: 113 LTEHLKLDP-GRLWVTVFEDD 132
>DP87_DICDI (Q04503) Prespore protein DP87 precursor| Length = 555 Score = 28.9 bits (63), Expect = 6.7 Identities = 21/66 (31%), Positives = 26/66 (39%), Gaps = 6/66 (9%) Frame = -3 Query: 320 GRRCNVRHDDGILHLSQPWLHVRLILKNIEADTEHGVSLEVLHQCNLVDHRATARV---- 153 G C V H DG ++ PW H + EHG +C LV HR R Sbjct: 165 GSACCVPHHDGCGNIQCPWGHYCV--------NEHG-------KCRLVPHRPPPRPPVDQ 209 Query: 152 --HQHC 141 +QHC Sbjct: 210 CRNQHC 215
>CARD9_RAT (Q9EPY0) Caspase recruitment domain-containing protein 9 (rCARD9)| Length = 536 Score = 28.5 bits (62), Expect = 8.7 Identities = 17/50 (34%), Positives = 24/50 (48%), Gaps = 7/50 (14%) Frame = -3 Query: 149 QHCLLLHH-------RQPLWVYQVVRRLVKHRVQAYHIGLPEDLLHAGSP 21 +H L L H ++ LW Q R L++ RVQ + + E LH SP Sbjct: 229 KHTLKLRHAMEQRPSQELLWDLQQERDLLQARVQELEVSVQEGKLHRNSP 278
>EP400_HUMAN (Q96L91) E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa| SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein) Length = 3160 Score = 28.5 bits (62), Expect = 8.7 Identities = 17/52 (32%), Positives = 24/52 (46%) Frame = -2 Query: 318 TQMQCEARRRHSSSQPALASCKAHPQKHRGRHGTWG*P*GAPPVQPRRSPGH 163 +Q A R +S + A+ AHP K R + G PP QP ++P H Sbjct: 1527 SQASASAPRHQPASASSTAASPAHPAKLRAQTTAQAFTPGQPPPQP-QAPSH 1577 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 67,756,907 Number of Sequences: 219361 Number of extensions: 1370716 Number of successful extensions: 4408 Number of sequences better than 10.0: 135 Number of HSP's better than 10.0 without gapping: 4249 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4375 length of database: 80,573,946 effective HSP length: 102 effective length of database: 58,199,124 effective search space used: 2968155324 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
