ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | baal1k04 |
|---|---|
| Clone Library Name | barley_pub |
>KIN11_ARATH (P92958) SNF1-related protein kinase catalytic alpha subunit KIN11| (EC 2.7.11.1) (AKIN11) (AKIN alpha1) Length = 512 Score = 289 bits (739), Expect = 5e-78 Identities = 140/158 (88%), Positives = 150/158 (94%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 L NY++GKTLGIGSFGKVKIAEH+ TGHKVAIKILNRRKIKNM+MEEKV+REIKILRLFM Sbjct: 17 LPNYKLGKTLGIGSFGKVKIAEHVVTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFM 76 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 HPHIIR YEVIE +DIYVVMEYVKSGELFDYIVEKGRLQE EAR FFQQIISGV+YCHR Sbjct: 77 HPHIIRQYEVIETTSDIYVVMEYVKSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHR 136 Query: 472 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFL 585 NMVVHRDLKPENLLLD+ C++KIADFGLSNVMRDGHFL Sbjct: 137 NMVVHRDLKPENLLLDSRCNIKIADFGLSNVMRDGHFL 174
>KIN10_ARATH (Q38997) SNF1-related protein kinase catalytic alpha subunit KIN10| (EC 2.7.11.1) (AKIN10) (AKIN alpha2) Length = 535 Score = 287 bits (734), Expect = 2e-77 Identities = 138/158 (87%), Positives = 149/158 (94%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 L NY++G+TLGIGSFG+VKIAEH TGHKVAIKILNRRKIKNM+MEEKV+REIKILRLFM Sbjct: 39 LPNYKLGRTLGIGSFGRVKIAEHALTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFM 98 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 HPHIIRLYEVIE P DIY+VMEYV SGELFDYIVEKGRLQE EAR FFQQIISGV+YCHR Sbjct: 99 HPHIIRLYEVIETPTDIYLVMEYVNSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHR 158 Query: 472 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFL 585 NMVVHRDLKPENLLLD+ C+VKIADFGLSN+MRDGHFL Sbjct: 159 NMVVHRDLKPENLLLDSKCNVKIADFGLSNIMRDGHFL 196
>RKIN1_SECCE (Q02723) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 502 Score = 239 bits (611), Expect = 3e-63 Identities = 119/171 (69%), Positives = 140/171 (81%), Gaps = 3/171 (1%) Frame = +1 Query: 82 MEAGGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVK 261 M+ GG+ LKNY +GK LG+G+F KV IAEH T HKVAIK+LNRR+++ +MEEK K Sbjct: 1 MDGGGEHSEALKNYYLGKILGVGTFAKVIIAEHKHTRHKVAIKVLNRRQMRAPEMEEKAK 60 Query: 262 REIKILRLFM---HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRF 432 REIKILRLF+ HPHIIR+YEVI P DI+VVMEY ++G+L DYI+EK RLQE EARR Sbjct: 61 REIKILRLFIDLIHPHIIRVYEVIVTPKDIFVVMEYCQNGDLLDYILEKRRLQEDEARRT 120 Query: 433 FQQIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFL 585 FQQIIS V+YCHRN VVHRDLKPENLLLD+ +VK+ADFGLSNVM DGHFL Sbjct: 121 FQQIISAVEYCHRNKVVHRDLKPENLLLDSKYNVKLADFGLSNVMHDGHFL 171
>AAPK1_RAT (P54645) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 548 Score = 224 bits (571), Expect = 1e-58 Identities = 103/156 (66%), Positives = 133/156 (85%) Frame = +1 Query: 118 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 297 +Y +G TLG+G+FGKVK+ +H TGHKVA+KILNR+KI+++D+ K++REI+ L+LF HP Sbjct: 15 HYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHP 74 Query: 298 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 477 HII+LY+VI P+DI++VMEYV GELFDYI + GRL E+E+RR FQQI+SGV YCHR+M Sbjct: 75 HIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHM 134 Query: 478 VVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFL 585 VVHRDLKPEN+LLD + + KIADFGLSN+M DG FL Sbjct: 135 VVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFL 170
>AAPK1_MOUSE (Q5EG47) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 548 Score = 224 bits (571), Expect = 1e-58 Identities = 103/156 (66%), Positives = 133/156 (85%) Frame = +1 Query: 118 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 297 +Y +G TLG+G+FGKVK+ +H TGHKVA+KILNR+KI+++D+ K++REI+ L+LF HP Sbjct: 15 HYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHP 74 Query: 298 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 477 HII+LY+VI P+DI++VMEYV GELFDYI + GRL E+E+RR FQQI+SGV YCHR+M Sbjct: 75 HIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHM 134 Query: 478 VVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFL 585 VVHRDLKPEN+LLD + + KIADFGLSN+M DG FL Sbjct: 135 VVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFL 170
>AAPK1_PONPY (Q5RDH5) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 550 Score = 224 bits (571), Expect = 1e-58 Identities = 103/156 (66%), Positives = 133/156 (85%) Frame = +1 Query: 118 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 297 +Y +G TLG+G+FGKVK+ +H TGHKVA+KILNR+KI+++D+ K++REI+ L+LF HP Sbjct: 17 HYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHP 76 Query: 298 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 477 HII+LY+VI P+DI++VMEYV GELFDYI + GRL E+E+RR FQQI+SGV YCHR+M Sbjct: 77 HIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHM 136 Query: 478 VVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFL 585 VVHRDLKPEN+LLD + + KIADFGLSN+M DG FL Sbjct: 137 VVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFL 172
>AAPK1_HUMAN (Q13131) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 550 Score = 224 bits (571), Expect = 1e-58 Identities = 103/156 (66%), Positives = 133/156 (85%) Frame = +1 Query: 118 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 297 +Y +G TLG+G+FGKVK+ +H TGHKVA+KILNR+KI+++D+ K++REI+ L+LF HP Sbjct: 17 HYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHP 76 Query: 298 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 477 HII+LY+VI P+DI++VMEYV GELFDYI + GRL E+E+RR FQQI+SGV YCHR+M Sbjct: 77 HIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHM 136 Query: 478 VVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFL 585 VVHRDLKPEN+LLD + + KIADFGLSN+M DG FL Sbjct: 137 VVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFL 172
>AAPK2_PONPY (Q5RD00) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 224 bits (570), Expect = 2e-58 Identities = 104/156 (66%), Positives = 130/156 (83%) Frame = +1 Query: 118 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 297 +Y +G TLG+G+FGKVKI EH TGHKVA+KILNR+KI+++D+ K+KREI+ L+LF HP Sbjct: 15 HYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHP 74 Query: 298 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 477 HII+LY+VI P D ++VMEYV GELFDYI + GR++E EARR FQQI+S V YCHR+M Sbjct: 75 HIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHM 134 Query: 478 VVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFL 585 VVHRDLKPEN+LLD + + KIADFGLSN+M DG FL Sbjct: 135 VVHRDLKPENVLLDAHMNAKIADFGLSNIMSDGEFL 170
>AAPK2_HUMAN (P54646) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 223 bits (568), Expect = 3e-58 Identities = 104/156 (66%), Positives = 130/156 (83%) Frame = +1 Query: 118 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 297 +Y +G TLG+G+FGKVKI EH TGHKVA+KILNR+KI+++D+ K+KREI+ L+LF HP Sbjct: 15 HYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHP 74 Query: 298 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 477 HII+LY+VI P D ++VMEYV GELFDYI + GR++E EARR FQQI+S V YCHR+M Sbjct: 75 HIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHM 134 Query: 478 VVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFL 585 VVHRDLKPEN+LLD + + KIADFGLSN+M DG FL Sbjct: 135 VVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFL 170
>AAPK2_PIG (Q28948) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 223 bits (567), Expect = 4e-58 Identities = 104/156 (66%), Positives = 129/156 (82%) Frame = +1 Query: 118 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 297 +Y +G TLG+G+FGKVKI EH TGHKVA+KILNR+KI+++D+ K+KREI+ L+LF HP Sbjct: 15 HYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHP 74 Query: 298 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 477 HII+LY+VI P D ++VMEYV GELFDYI + GR++E EARR FQQI+S V YCHR+M Sbjct: 75 HIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHM 134 Query: 478 VVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFL 585 VVHRDLKPEN+LLD + KIADFGLSN+M DG FL Sbjct: 135 VVHRDLKPENVLLDAQMNAKIADFGLSNMMSDGEFL 170
>AAPK2_RAT (Q09137) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 222 bits (565), Expect = 7e-58 Identities = 104/156 (66%), Positives = 129/156 (82%) Frame = +1 Query: 118 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 297 +Y +G TLG+G+FGKVKI EH TGHKVA+KILNR+KI+++D+ K+KREI+ L+LF HP Sbjct: 15 HYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHP 74 Query: 298 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 477 HII+LY+VI P D ++VMEYV GELFDYI + GR++E EARR FQQI+S V YCHR+M Sbjct: 75 HIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEVEARRLFQQILSAVDYCHRHM 134 Query: 478 VVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFL 585 VVHRDLKPEN+LLD + KIADFGLSN+M DG FL Sbjct: 135 VVHRDLKPENVLLDAQMNAKIADFGLSNMMSDGEFL 170
>AAPK2_CAEEL (Q95ZQ4) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMP-activated kinase 2) Length = 626 Score = 220 bits (560), Expect = 3e-57 Identities = 105/156 (67%), Positives = 131/156 (83%) Frame = +1 Query: 118 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 297 +Y + +TLG+G+FGKVK+ H T +KVA+KILNR+KIK++D+ K++REI+ L LF HP Sbjct: 86 HYILKETLGVGTFGKVKVGIHETTQYKVAVKILNRQKIKSLDVVGKIRREIQNLSLFRHP 145 Query: 298 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 477 HIIRLY+VI P+DI+++ME+V GELFDYIV+ GRL+ EARRFFQQIISGV YCHR+M Sbjct: 146 HIIRLYQVISTPSDIFMIMEHVSGGELFDYIVKHGRLKTAEARRFFQQIISGVDYCHRHM 205 Query: 478 VVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFL 585 VVHRDLKPENLLLD +VKIADFGLSN+M DG FL Sbjct: 206 VVHRDLKPENLLLDEQNNVKIADFGLSNIMTDGDFL 241
>SNF1_CANGA (Q00372) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 612 Score = 211 bits (536), Expect = 2e-54 Identities = 100/162 (61%), Positives = 132/162 (81%) Frame = +1 Query: 100 DGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKIL 279 DG+ + NY+I KTLG GSFGKVK+A H+ TG KVA+KI+N++ + DM+ +++REI L Sbjct: 32 DGSRVGNYQIVKTLGEGSFGKVKLAYHVTTGQKVALKIINKKVLAKSDMQGRIEREISYL 91 Query: 280 RLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQ 459 RL HPHII+LY+VI++ +I +V+EY ELFDYIV++ ++ EQEARRFFQQIIS V+ Sbjct: 92 RLLRHPHIIKLYDVIKSKDEIIMVIEYA-GNELFDYIVQRNKMSEQEARRFFQQIISAVE 150 Query: 460 YCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFL 585 YCHR+ +VHRDLKPENLLLD + +VKIADFGLSN+M DG+FL Sbjct: 151 YCHRHKIVHRDLKPENLLLDEHLNVKIADFGLSNIMTDGNFL 192
>SNF1_YEAST (P06782) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 633 Score = 208 bits (529), Expect = 1e-53 Identities = 100/162 (61%), Positives = 130/162 (80%) Frame = +1 Query: 100 DGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKIL 279 DG + NY+I KTLG GSFGKVK+A H TG KVA+KI+N++ + DM+ +++REI L Sbjct: 48 DGAHIGNYQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGRIEREISYL 107 Query: 280 RLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQ 459 RL HPHII+LY+VI++ +I +V+EY ELFDYIV++ ++ EQEARRFFQQIIS V+ Sbjct: 108 RLLRHPHIIKLYDVIKSKDEIIMVIEYA-GNELFDYIVQRDKMSEQEARRFFQQIISAVE 166 Query: 460 YCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFL 585 YCHR+ +VHRDLKPENLLLD + +VKIADFGLSN+M DG+FL Sbjct: 167 YCHRHKIVHRDLKPENLLLDEHLNVKIADFGLSNIMTDGNFL 208
>SNF1_CANAL (P52497) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 620 Score = 205 bits (522), Expect = 7e-53 Identities = 98/168 (58%), Positives = 132/168 (78%) Frame = +1 Query: 82 MEAGGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVK 261 ++ N + Y+I KTLG GSFGKVK+A+H+ TG KVA+KI+NR+ + DM+ +V+ Sbjct: 40 IDPAANPANRIGRYQILKTLGEGSFGKVKLAQHLGTGQKVALKIINRKTLAKSDMQGRVE 99 Query: 262 REIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQ 441 REI LRL HPHII+LY+VI++ +I +V+E+ ELFDYIV++G++ E EARRFFQQ Sbjct: 100 REISYLRLLRHPHIIKLYDVIKSKDEIIMVIEFAGK-ELFDYIVQRGKMPEDEARRFFQQ 158 Query: 442 IISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFL 585 II+ V+YCHR+ +VHRDLKPENLLLD+ +VKIADFGLSN+M DG+FL Sbjct: 159 IIAAVEYCHRHKIVHRDLKPENLLLDDQLNVKIADFGLSNIMTDGNFL 206
>SNF1_CANTR (O94168) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 619 Score = 205 bits (522), Expect = 7e-53 Identities = 98/160 (61%), Positives = 130/160 (81%) Frame = +1 Query: 106 NPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRL 285 N + Y+I KTLG GSFGKVK+A+H+ TG KVA+KI+NR+ + DM+ +V+REI LRL Sbjct: 47 NRIGRYQIIKTLGEGSFGKVKLAQHVGTGQKVALKIINRKTLAKSDMQGRVEREISYLRL 106 Query: 286 FMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYC 465 HPHII+LY+VI++ +I +V+E+ ELFDYIV++G++ E EARRFFQQII+ V+YC Sbjct: 107 LRHPHIIKLYDVIKSKDEIIMVIEFAGK-ELFDYIVQRGKMPEDEARRFFQQIIAAVEYC 165 Query: 466 HRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFL 585 HR+ +VHRDLKPENLLLD+ +VKIADFGLSN+M DG+FL Sbjct: 166 HRHKIVHRDLKPENLLLDDQLNVKIADFGLSNIMTDGNFL 205
>SNF1_SCHPO (O74536) SNF1-like protein kinase ssp2 (EC 2.7.11.1)| Length = 576 Score = 203 bits (517), Expect = 3e-52 Identities = 99/155 (63%), Positives = 122/155 (78%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 Y I +TLG GSFGKVK+A H KT KVA+K ++R+ +K DM +V+REI L+L HPH Sbjct: 34 YIIRETLGEGSFGKVKLATHYKTQQKVALKFISRQLLKKSDMHMRVEREISYLKLLRHPH 93 Query: 301 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 480 II+LY+VI P DI +V+EY GELFDYIVEK R+ E E RRFFQQII ++YCHR+ + Sbjct: 94 IIKLYDVITTPTDIVMVIEYA-GGELFDYIVEKKRMTEDEGRRFFQQIICAIEYCHRHKI 152 Query: 481 VHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFL 585 VHRDLKPENLLLD+N +VKIADFGLSN+M DG+FL Sbjct: 153 VHRDLKPENLLLDDNLNVKIADFGLSNIMTDGNFL 187
>AAPK1_CAEEL (P45894) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMP-activated kinase 1) Length = 589 Score = 187 bits (475), Expect = 2e-47 Identities = 92/156 (58%), Positives = 114/156 (73%) Frame = +1 Query: 118 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 297 N+ I +T+G G+FG VK HI+TG+ VAIKILNR ++K + K + EI L+ HP Sbjct: 23 NFVIKETIGKGAFGAVKRGTHIQTGYDVAIKILNRGRMKGLGTVNKTRNEIDNLQKLTHP 82 Query: 298 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 477 HI RL+ VI P+DI++VME V GELF YI KG L +E+RR+FQQIISGV YCH +M Sbjct: 83 HITRLFRVISTPSDIFLVMELVSGGELFSYITRKGALPIRESRRYFQQIISGVSYCHNHM 142 Query: 478 VVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFL 585 +VHRDLKPENLLLD N ++KIADFGLSN M DG L Sbjct: 143 IVHRDLKPENLLLDANKNIKIADFGLSNYMTDGDLL 178
>MARK2_RAT (O08679) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1) Length = 722 Score = 174 bits (440), Expect = 2e-43 Identities = 84/172 (48%), Positives = 125/172 (72%), Gaps = 1/172 (0%) Frame = +1 Query: 73 RWKMEAGGKDGNP-LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDME 249 R + A D P + NYR+ KT+G G+F KVK+A HI TG +VA+KI+++ ++ + ++ Sbjct: 36 RGRNSATSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQ 95 Query: 250 EKVKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARR 429 K+ RE++I+++ HP+I++L+EVIE +Y+VMEY GE+FDY+V GR++E+EAR Sbjct: 96 -KLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARA 154 Query: 430 FFQQIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFL 585 F+QI+S VQYCH+ +VHRDLK ENLLLD + ++KIADFG SN G+ L Sbjct: 155 KFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKL 206
>MARK2_HUMAN (Q7KZI7) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog) Length = 788 Score = 174 bits (440), Expect = 2e-43 Identities = 84/172 (48%), Positives = 125/172 (72%), Gaps = 1/172 (0%) Frame = +1 Query: 73 RWKMEAGGKDGNP-LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDME 249 R + A D P + NYR+ KT+G G+F KVK+A HI TG +VA+KI+++ ++ + ++ Sbjct: 36 RGRNSATSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQ 95 Query: 250 EKVKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARR 429 K+ RE++I+++ HP+I++L+EVIE +Y+VMEY GE+FDY+V GR++E+EAR Sbjct: 96 -KLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARA 154 Query: 430 FFQQIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFL 585 F+QI+S VQYCH+ +VHRDLK ENLLLD + ++KIADFG SN G+ L Sbjct: 155 KFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKL 206
>MARK1_HUMAN (Q9P0L2) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) Length = 795 Score = 173 bits (438), Expect = 4e-43 Identities = 79/156 (50%), Positives = 118/156 (75%) Frame = +1 Query: 118 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 297 NYR+ KT+G G+F KVK+A H+ TG +VA+KI+++ ++ ++ K+ RE++I+++ HP Sbjct: 59 NYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQ-KLFREVRIMKILNHP 117 Query: 298 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 477 +I++L+EVIE +Y+VMEY GE+FDY+V GR++E+EAR F+QI+S VQYCH+ Sbjct: 118 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKY 177 Query: 478 VVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFL 585 +VHRDLK ENLLLD + ++KIADFG SN G+ L Sbjct: 178 IVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKL 213
>CPK24_ARATH (Q9LDI3) CBL-interacting serine/threonine-protein kinase 24 (EC| 2.7.11.1) (SNF1-related kinase 3.11) (SALT OVERLY SENSITIVE 2 protein) Length = 446 Score = 172 bits (437), Expect = 5e-43 Identities = 79/152 (51%), Positives = 114/152 (75%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 Y +G+T+G G+F KVK A + TG VAIKI+ + I M +++KREI I+++ HP+ Sbjct: 11 YEVGRTIGEGTFAKVKFARNTDTGDNVAIKIMAKSTILKNRMVDQIKREISIMKIVRHPN 70 Query: 301 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 480 I+RLYEV+ +P+ IY+V+E+V GELFD IV KGRL+E E+R++FQQ++ V +CH V Sbjct: 71 IVRLYEVLASPSKIYIVLEFVTGGELFDRIVHKGRLEESESRKYFQQLVDAVAHCHCKGV 130 Query: 481 VHRDLKPENLLLDNNCDVKIADFGLSNVMRDG 576 HRDLKPENLLLD N ++K++DFGLS + ++G Sbjct: 131 YHRDLKPENLLLDTNGNLKVSDFGLSALPQEG 162
>MARK1_RAT (O08678) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) Length = 793 Score = 172 bits (436), Expect = 6e-43 Identities = 79/156 (50%), Positives = 118/156 (75%) Frame = +1 Query: 118 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 297 NYR+ KT+G G+F KVK+A H+ TG +VA+KI+++ ++ ++ K+ RE++I+++ HP Sbjct: 59 NYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQ-KLFREVRIMKILNHP 117 Query: 298 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 477 +I++L+EVIE +Y+VMEY GE+FDY+V GR++E+EAR F+QI+S VQYCH+ Sbjct: 118 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKC 177 Query: 478 VVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFL 585 +VHRDLK ENLLLD + ++KIADFG SN G+ L Sbjct: 178 IVHRDLKAENLLLDADMNIKIADFGFSNEFTVGNKL 213
>MARK1_MOUSE (Q8VHJ5) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) (ELKL motif serine/threonine-protein kinase 3) Length = 795 Score = 172 bits (436), Expect = 6e-43 Identities = 79/156 (50%), Positives = 118/156 (75%) Frame = +1 Query: 118 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 297 NYR+ KT+G G+F KVK+A H+ TG +VA+KI+++ ++ ++ K+ RE++I+++ HP Sbjct: 59 NYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQ-KLFREVRIMKILNHP 117 Query: 298 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 477 +I++L+EVIE +Y+VMEY GE+FDY+V GR++E+EAR F+QI+S VQYCH+ Sbjct: 118 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKC 177 Query: 478 VVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFL 585 +VHRDLK ENLLLD + ++KIADFG SN G+ L Sbjct: 178 IVHRDLKAENLLLDADMNIKIADFGFSNEFTVGNKL 213
>MARK3_MOUSE (Q03141) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| (MPK-10) (ELKL motif kinase 2) Length = 753 Score = 171 bits (433), Expect = 1e-42 Identities = 78/148 (52%), Positives = 115/148 (77%) Frame = +1 Query: 118 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 297 NYR+ KT+G G+F KVK+A HI TG +VAIKI+++ ++ ++ K+ RE++I+++ HP Sbjct: 55 NYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQ-KLFREVRIMKILNHP 113 Query: 298 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 477 +I++L+EVIE +Y++MEY GE+FDY+V GR++E+EAR F+QI+S VQYCH+ Sbjct: 114 NIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKR 173 Query: 478 VVHRDLKPENLLLDNNCDVKIADFGLSN 561 +VHRDLK ENLLLD + ++KIADFG SN Sbjct: 174 IVHRDLKAENLLLDADMNIKIADFGFSN 201
>MARK2_MOUSE (Q05512) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1) Length = 776 Score = 171 bits (432), Expect = 2e-42 Identities = 83/172 (48%), Positives = 124/172 (72%), Gaps = 1/172 (0%) Frame = +1 Query: 73 RWKMEAGGKDGNP-LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDME 249 R + A D P + NYR+ KT+G G+F KVK+A HI TG +VA+KI+++ ++ + ++ Sbjct: 36 RGRNSATSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQ 95 Query: 250 EKVKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARR 429 K+ RE++I+++ HP+I++L+EVIE +Y+VMEY GE+FDY+V GR++E+EAR Sbjct: 96 -KLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARA 154 Query: 430 FFQQIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFL 585 F+QI+ VQYCH+ +VHRDLK ENLLLD + ++KIADFG SN G+ L Sbjct: 155 KFRQIVLHVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKL 206
>MARK3_RAT (Q8VHF0) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| Length = 797 Score = 169 bits (429), Expect = 4e-42 Identities = 77/148 (52%), Positives = 114/148 (77%) Frame = +1 Query: 118 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 297 NYR+ KT+G G+F KVK+A HI TG +VAIKI+++ ++ ++ K+ RE++I+++ HP Sbjct: 55 NYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQ-KLFREVRIMKILNHP 113 Query: 298 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 477 +I++L+EVIE +Y++MEY GE+FDY+V GR++E+EAR F+QI+S VQYCH+ Sbjct: 114 NIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKR 173 Query: 478 VVHRDLKPENLLLDNNCDVKIADFGLSN 561 +VHRDLK ENLLLD + ++KI DFG SN Sbjct: 174 IVHRDLKAENLLLDADMNIKITDFGFSN 201
>NUAK1_HUMAN (O60285) NUAK family, SNF1-like kinase 1 (EC 2.7.11.1)| (AMPK-related protein kinase 5) Length = 661 Score = 167 bits (423), Expect = 2e-41 Identities = 82/155 (52%), Positives = 109/155 (70%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 Y + +TLG G++GKVK A +G VAIK + + KIK+ ++REI+I+ HPH Sbjct: 55 YELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHPH 114 Query: 301 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 480 II +YEV E I ++MEY GEL+DYI E+ RL E+E R FF+QI+S V YCH+N V Sbjct: 115 IISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNGV 174 Query: 481 VHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFL 585 VHRDLK EN+LLD+NC++KIADFGLSN+ + FL Sbjct: 175 VHRDLKLENILLDDNCNIKIADFGLSNLYQKDKFL 209
>MARK4_MOUSE (Q8CIP4) MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1)| Length = 752 Score = 167 bits (422), Expect = 3e-41 Identities = 78/148 (52%), Positives = 113/148 (76%) Frame = +1 Query: 118 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 297 NYR+ +T+G G+F KVK+A HI TG +VAIKI+++ ++ N +K+ RE++I++ HP Sbjct: 58 NYRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQL-NPSSLQKLFREVRIMKGLNHP 116 Query: 298 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 477 +I++L+EVIE +Y+VMEY +GE+FDY+V GR++E+EAR F+QI+S V YCH+ Sbjct: 117 NIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKN 176 Query: 478 VVHRDLKPENLLLDNNCDVKIADFGLSN 561 +VHRDLK ENLLLD ++KIADFG SN Sbjct: 177 IVHRDLKAENLLLDAEANIKIADFGFSN 204
>MARK4_HUMAN (Q96L34) MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase-like 1) Length = 752 Score = 167 bits (422), Expect = 3e-41 Identities = 78/148 (52%), Positives = 113/148 (76%) Frame = +1 Query: 118 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 297 NYR+ +T+G G+F KVK+A HI TG +VAIKI+++ ++ N +K+ RE++I++ HP Sbjct: 58 NYRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQL-NPSSLQKLFREVRIMKGLNHP 116 Query: 298 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 477 +I++L+EVIE +Y+VMEY +GE+FDY+V GR++E+EAR F+QI+S V YCH+ Sbjct: 117 NIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKN 176 Query: 478 VVHRDLKPENLLLDNNCDVKIADFGLSN 561 +VHRDLK ENLLLD ++KIADFG SN Sbjct: 177 IVHRDLKAENLLLDAEANIKIADFGFSN 204
>NUAK1_MOUSE (Q641K5) NUAK family, SNF1-like kinase 1 (EC 2.7.11.1)| Length = 658 Score = 166 bits (420), Expect = 5e-41 Identities = 84/156 (53%), Positives = 112/156 (71%), Gaps = 1/156 (0%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKN-MDMEEKVKREIKILRLFMHP 297 Y + +TLG G++GKVK A +G VAIK + + KIK+ +DM ++REI+I+ HP Sbjct: 56 YELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDELDMVH-IRREIEIMSSLNHP 114 Query: 298 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 477 HII +YEV E I ++MEY GEL+DYI E+ RL E+E R FF+QI+S V YCH+N Sbjct: 115 HIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNG 174 Query: 478 VVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFL 585 VVHRDLK EN+LLD+NC++KIADFGLSN+ + FL Sbjct: 175 VVHRDLKLENILLDDNCNIKIADFGLSNLYQKDKFL 210
>SN1L2_MOUSE (Q8CFH6) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Salt-inducible kinase 2) Length = 931 Score = 165 bits (417), Expect = 1e-40 Identities = 80/155 (51%), Positives = 110/155 (70%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 Y I TLG G+F VK+ H T +VAIKI+++ ++ +++E K+ RE++I+++ HPH Sbjct: 20 YDIEGTLGKGNFAVVKLGRHRTTKTEVAIKIIDKSQLDAVNLE-KIYREVQIMKMLDHPH 78 Query: 301 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 480 II+LY+V+E + +Y+V EY K+GE+FDY+ GRL E EARR F QI+S V YCH V Sbjct: 79 IIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKV 138 Query: 481 VHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFL 585 VHRDLK ENLLLDNN ++KIADFG N + G L Sbjct: 139 VHRDLKAENLLLDNNMNIKIADFGFGNFFKTGELL 173
>BRSK1_HUMAN (Q8TDC3) BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1| kinase) (SAD1A) Length = 794 Score = 164 bits (416), Expect = 1e-40 Identities = 80/160 (50%), Positives = 114/160 (71%) Frame = +1 Query: 85 EAGGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKR 264 E G+ + YR+ KTLG G G VK+ H TG KVAIKI+NR K+ + KV+R Sbjct: 38 EERGRHAQYVGPYRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLM-KVER 96 Query: 265 EIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQI 444 EI IL+L HPH+++L++V E +Y+V+E+V GELFDY+V+KGRL +EAR+FF+QI Sbjct: 97 EIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQI 156 Query: 445 ISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNV 564 +S + +CH + HRDLKPENLLLD +++IADFG++++ Sbjct: 157 VSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASL 196
>BRSK2_HUMAN (Q8IWQ3) BR serine/threonine-protein kinase 2 (EC 2.7.11.1)| (Serine/threonine-protein kinase 29) (SAD1B) Length = 736 Score = 164 bits (415), Expect = 2e-40 Identities = 83/166 (50%), Positives = 117/166 (70%), Gaps = 5/166 (3%) Frame = +1 Query: 82 MEAGGKDGNP-----LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDM 246 M + GKDG + YR+ KTLG G G VK+ H T KVAIKI+NR K+ + Sbjct: 1 MTSTGKDGGAQHAQYVGPYRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESVL 60 Query: 247 EEKVKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEAR 426 KV+REI IL+L HPH+++L++V E +Y+V+E+V GELFDY+V+KGRL +EAR Sbjct: 61 M-KVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEAR 119 Query: 427 RFFQQIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNV 564 +FF+QIIS + +CH + + HRDLKPENLLLD +++IADFG++++ Sbjct: 120 KFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASL 165
>SN1L2_HUMAN (Q9H0K1) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Qin-induced kinase) Length = 926 Score = 164 bits (415), Expect = 2e-40 Identities = 79/155 (50%), Positives = 110/155 (70%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 Y I TLG G+F VK+ H T +VAIKI+++ ++ +++E K+ RE++I+++ HPH Sbjct: 20 YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLE-KIYREVQIMKMLDHPH 78 Query: 301 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 480 II+LY+V+E + +Y+V EY K+GE+FDY+ GRL E EARR F QI+S V YCH + Sbjct: 79 IIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKI 138 Query: 481 VHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFL 585 VHRDLK ENLLLDNN ++KIADFG N + G L Sbjct: 139 VHRDLKAENLLLDNNMNIKIADFGFGNFFKSGELL 173
>SN1L1_HUMAN (P57059) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) Length = 783 Score = 162 bits (409), Expect = 9e-40 Identities = 75/152 (49%), Positives = 110/152 (72%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 Y I +TLG G+F VK+A H T +VAIKI+++ ++ + ++E K+ RE+++++L HPH Sbjct: 27 YDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNLE-KIYREVQLMKLLNHPH 85 Query: 301 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 480 II+LY+V+E +Y+V E+ K+GE+FDY+ G L E EAR+ F QI+S V+YCH + + Sbjct: 86 IIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHDHHI 145 Query: 481 VHRDLKPENLLLDNNCDVKIADFGLSNVMRDG 576 VHRDLK ENLLLD N D+K+ADFG N + G Sbjct: 146 VHRDLKTENLLLDGNMDIKLADFGFGNFYKSG 177
>SN1L2_PONPY (Q5REX1) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) Length = 925 Score = 162 bits (409), Expect = 9e-40 Identities = 78/155 (50%), Positives = 109/155 (70%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 Y I TLG G+F VK+ H T +VAIKI+++ ++ +++E K+ RE++I+++ HPH Sbjct: 20 YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLE-KIYREVQIMKMLDHPH 78 Query: 301 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 480 II+LY+V+E + +Y+V EY K+GE+FDY+ GRL E EARR F QI+S V YCH + Sbjct: 79 IIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKI 138 Query: 481 VHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFL 585 VHRDLK ENLLLDNN ++KIADF N + G L Sbjct: 139 VHRDLKAENLLLDNNMNIKIADFSFGNFFKSGELL 173
>CIPK1_ARATH (Q8RWC9) CBL-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (SOS2-like protein kinase PKS13) (SNF1-related kinase 3.16) Length = 444 Score = 160 bits (405), Expect = 3e-39 Identities = 77/162 (47%), Positives = 109/162 (67%) Frame = +1 Query: 73 RWKMEAGGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEE 252 R + E + G L Y +G+TLG G+FGKVK A+ +GH A+KI+++ +I +++ Sbjct: 4 RQEEEKKAEKGMRLGKYELGRTLGEGNFGKVKFAKDTVSGHSFAVKIIDKSRIADLNFSL 63 Query: 253 KVKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRF 432 ++KREI+ L++ HPHI+RL+EV+ + I +VME V GELFD IV G+L E + R+ Sbjct: 64 QIKREIRTLKMLKHPHIVRLHEVLASKTKINMVMELVTGGELFDRIVSNGKLTETDGRKM 123 Query: 433 FQQIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLS 558 FQQ+I G+ YCH V HRDLK EN+LLD +KI DFGLS Sbjct: 124 FQQLIDGISYCHSKGVFHRDLKLENVLLDAKGHIKITDFGLS 165
>SN1L1_RAT (Q9R1U5) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (Salt-inducible protein kinase) (Protein kinase KID2) Length = 776 Score = 159 bits (402), Expect = 6e-39 Identities = 73/152 (48%), Positives = 110/152 (72%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 Y + +TLG G+F VK+A H T +VAIKI+++ ++ + ++E K+ RE+++++L HP+ Sbjct: 27 YDVERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNLE-KIYREVQLMKLLNHPN 85 Query: 301 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 480 II+LY+V+E +Y+V E+ K+GE+FDY+ G L E EAR+ F QI+S V+YCH + + Sbjct: 86 IIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHNHHI 145 Query: 481 VHRDLKPENLLLDNNCDVKIADFGLSNVMRDG 576 VHRDLK ENLLLD N D+K+ADFG N + G Sbjct: 146 VHRDLKTENLLLDGNMDIKLADFGFGNFYKPG 177
>SN1L1_MOUSE (Q60670) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (HRT-20) (Myocardial SNF1-like kinase) Length = 779 Score = 159 bits (402), Expect = 6e-39 Identities = 73/152 (48%), Positives = 111/152 (73%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 Y + +TLG G+F VK+A H T +VAIKI+++ ++ + ++E K+ RE+++++L HP+ Sbjct: 27 YDVERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNLE-KIYREVQLMKLLNHPN 85 Query: 301 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 480 II+LY+V+E +Y+V E+ K+GE+FDY+ G L E EAR+ F QI+S V+YCH + + Sbjct: 86 IIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARQKFWQILSAVEYCHNHHI 145 Query: 481 VHRDLKPENLLLDNNCDVKIADFGLSNVMRDG 576 VHRDLK ENLLLD+N D+K+ADFG N + G Sbjct: 146 VHRDLKTENLLLDSNMDIKLADFGFGNFYKPG 177
>MARK3_HUMAN (P27448) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| (Cdc25C-associated protein kinase 1) (cTAK1) (C-TAK1) (Serine/threonine protein kinase p78) (Ser/Thr protein kinase PAR-1) (Protein kinase STK10) Length = 776 Score = 158 bits (399), Expect = 1e-38 Identities = 78/171 (45%), Positives = 115/171 (67%), Gaps = 23/171 (13%) Frame = +1 Query: 118 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 297 NYR+ KT+G G+F KVK+A HI TG +VAIKI+++ ++ ++ K+ RE++I+++ HP Sbjct: 55 NYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQ-KLFREVRIMKILNHP 113 Query: 298 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQ------------ 441 +I++L+EVIE +Y++MEY GE+FDY+V GR++E+EAR F+Q Sbjct: 114 NIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQGCQAGQTIKVQV 173 Query: 442 -----------IISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSN 561 I+S VQYCH+ +VHRDLK ENLLLD + ++KIADFG SN Sbjct: 174 SFDLLSLMFTFIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSN 224
>CPK15_ARATH (P92937) CBL-interacting serine/threonine-protein kinase 15 (EC| 2.7.11.1) (Serine/threonine-protein kinase ATPK10) (SOS2-like protein kinase PKS3) (SOS-interacting protein 2) (SNF1-related kinase 3.1) Length = 421 Score = 157 bits (398), Expect = 2e-38 Identities = 76/146 (52%), Positives = 106/146 (72%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 Y +GK LG G+F KV A H+KTG VAIK++++ +I + M E++KREI +RL HP+ Sbjct: 12 YEVGKFLGQGTFAKVYHARHLKTGDSVAIKVIDKERILKVGMTEQIKREISAMRLLRHPN 71 Query: 301 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 480 I+ L+EV+ + IY VME+VK GELF+ V G+L+E AR++FQQ++ V +CH V Sbjct: 72 IVELHEVMATKSKIYFVMEHVKGGELFNK-VSTGKLREDVARKYFQQLVRAVDFCHSRGV 130 Query: 481 VHRDLKPENLLLDNNCDVKIADFGLS 558 HRDLKPENLLLD + ++KI+DFGLS Sbjct: 131 CHRDLKPENLLLDEHGNLKISDFGLS 156
>SN1L2_CHICK (Q9IA88) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Qin-induced kinase) Length = 798 Score = 157 bits (397), Expect = 2e-38 Identities = 74/152 (48%), Positives = 109/152 (71%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 Y I +TLG G+F VK+A H T +VAIKI+++ ++ ++E K+ RE++I++L HPH Sbjct: 26 YDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDPSNLE-KIYREVQIMKLLNHPH 84 Query: 301 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 480 II+LY+V+E +Y+V E+ K+GE+FD++ G L E EAR+ F QI+S V+YCH + + Sbjct: 85 IIKLYQVMETKDMLYIVTEFAKNGEMFDHLTSNGHLSESEARKKFWQILSAVEYCHSHHI 144 Query: 481 VHRDLKPENLLLDNNCDVKIADFGLSNVMRDG 576 VHRDLK ENLLLD N ++K+ADFG N + G Sbjct: 145 VHRDLKTENLLLDANMNIKLADFGFGNFYKSG 176
>CPK11_ARATH (O22932) CBL-interacting serine/threonine-protein kinase 11 (EC| 2.7.11.1) (SOS2-like protein kinase PKS5) (SOS-interacting protein 4) (SNF1-related kinase 3.22) Length = 435 Score = 157 bits (396), Expect = 3e-38 Identities = 80/163 (49%), Positives = 110/163 (67%), Gaps = 3/163 (1%) Frame = +1 Query: 79 KMEAGGKDGNP--LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKI-KNMDME 249 ++ AG D N Y +GK LG G+F KV A +TG VA+KILN++K+ N + Sbjct: 5 EIAAGSGDNNDALFGKYELGKLLGCGAFAKVFHARDRRTGQSVAVKILNKKKLLTNPALA 64 Query: 250 EKVKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARR 429 +KREI I+R HP+I++L+EV+ + I+ ME+VK GELF+ I + GRL E +RR Sbjct: 65 NNIKREISIMRRLSHPNIVKLHEVMATKSKIFFAMEFVKGGELFNKISKHGRLSEDLSRR 124 Query: 430 FFQQIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLS 558 +FQQ+IS V YCH V HRDLKPENLL+D N ++K++DFGLS Sbjct: 125 YFQQLISAVGYCHARGVYHRDLKPENLLIDENGNLKVSDFGLS 167
>CIPK1_ORYSA (Q6X4A2) CIPK-like protein 1 (EC 2.7.11.1) (OsCK1)| Length = 449 Score = 156 bits (394), Expect = 5e-38 Identities = 71/146 (48%), Positives = 110/146 (75%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 Y +G+T+G G+F KV+ A++ + VAIKIL++ K++ + E+++REI ++L HP+ Sbjct: 20 YELGRTIGEGTFAKVRFAKNTENDEPVAIKILDKEKVQKHRLVEQIRREICTMKLVKHPN 79 Query: 301 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 480 ++RL+EV+ + A I++V+EYV GELF+ I GRL+E+EAR++FQQ+I+ V YCH V Sbjct: 80 VVRLFEVMGSKARIFIVLEYVTGGELFEIIATNGRLKEEEARKYFQQLINAVDYCHSRGV 139 Query: 481 VHRDLKPENLLLDNNCDVKIADFGLS 558 HRDLK ENLLLD + ++K++DFGLS Sbjct: 140 YHRDLKLENLLLDASGNLKVSDFGLS 165
>GIN4_YEAST (Q12263) Serine/threonine-protein kinase GIN4 (EC 2.7.11.1)| Length = 1142 Score = 153 bits (386), Expect = 4e-37 Identities = 75/174 (43%), Positives = 116/174 (66%), Gaps = 14/174 (8%) Frame = +1 Query: 106 NPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEK---------- 255 N + +++G+TLG+GS GKV++A + TG + A+K++++ ++ Sbjct: 14 NTIGPWKLGETLGLGSTGKVQLARNGSTGQEAAVKVISKAVFNTGNVSGTSIVGSTTPDA 73 Query: 256 ----VKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEA 423 ++REI I++L HP+++RLY+V E D+Y+V+EY + GELF+ +VE+G L E EA Sbjct: 74 LPYGIEREIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEA 133 Query: 424 RRFFQQIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFL 585 RFF+QII GV YCH +VHRDLKPENLLLD+ ++KIADFG++ + +G L Sbjct: 134 IRFFRQIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMAALETEGKLL 187
>KCC4_YEAST (P25389) Probable serine/threonine-protein kinase KCC4 (EC| 2.7.11.1) Length = 1037 Score = 151 bits (382), Expect = 1e-36 Identities = 71/174 (40%), Positives = 116/174 (66%), Gaps = 8/174 (4%) Frame = +1 Query: 88 AGGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMD-------- 243 + K + + +++G+TLG GS GKV++A+H +TGH+ A+K++++ N Sbjct: 10 SAAKPSSTIGPWKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSV 69 Query: 244 MEEKVKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEA 423 + ++REI I++L HP+++ LY+V E ++Y+++EY + GELF+ +V+ G L E+EA Sbjct: 70 LPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREA 129 Query: 424 RRFFQQIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFL 585 F+QII G+ YCH +VHRDLKPENLLLD+ ++KIADFG++ + D L Sbjct: 130 INCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDADLL 183
>MELK_MOUSE (Q61846) Maternal embryonic leucine zipper kinase (EC 2.7.11.1)| (Protein kinase PK38) (mPK38) Length = 643 Score = 139 bits (351), Expect = 5e-33 Identities = 72/148 (48%), Positives = 97/148 (65%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 LK Y + +T+G G F KVK+A H+ TG VAIKI+++ + + D+ +VK EI L+ Sbjct: 8 LKYYELYETIGTGGFAKVKLACHVLTGEMVAIKIMDKNALGS-DLP-RVKTEIDALKSLR 65 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 H HI +LY V+E I++V+EY GELFDYI+ + RL E+E R F+QI+S V Y H Sbjct: 66 HQHICQLYHVLETKNKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQILSAVAYVHS 125 Query: 472 NMVVHRDLKPENLLLDNNCDVKIADFGL 555 HRDLKPENLL D N +K+ DFGL Sbjct: 126 QGYAHRDLKPENLLFDENHKLKLIDFGL 153
>MELK_HUMAN (Q14680) Maternal embryonic leucine zipper kinase (EC 2.7.11.1)| (hMELK) (Protein kinase PK38) (hPK38) Length = 651 Score = 137 bits (346), Expect = 2e-32 Identities = 71/148 (47%), Positives = 97/148 (65%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 LK Y + +T+G G F KVK+A HI TG VAIKI+++ + + D+ ++K EI+ L+ Sbjct: 8 LKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGS-DLP-RIKTEIEALKNLR 65 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 H HI +LY V+E I++V+EY GELFDYI+ + RL E+E R F+QI+S V Y H Sbjct: 66 HQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHS 125 Query: 472 NMVVHRDLKPENLLLDNNCDVKIADFGL 555 HRDLKPENLL D +K+ DFGL Sbjct: 126 QGYAHRDLKPENLLFDEYHKLKLIDFGL 153
>KIN1_SCHPO (P22987) Protein kinase kin1 (EC 2.7.11.1)| Length = 891 Score = 135 bits (340), Expect = 9e-32 Identities = 73/169 (43%), Positives = 100/169 (59%), Gaps = 18/169 (10%) Frame = +1 Query: 118 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNR-----RKIKNMDMEEKVK------- 261 NY +GKT+G GS GKVK+A H+KTG + AIKI+ R K K E K Sbjct: 124 NYVLGKTIGAGSMGKVKVAHHLKTGEQFAIKIVTRLHPDITKAKAAASAEATKAAQSEKN 183 Query: 262 ------REIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEA 423 RE + L HP+I +V + Y+V E+V G++ DYI+ G+L+E++A Sbjct: 184 KEIRTVREAALSTLLRHPYICEARDVYITNSHYYMVFEFVDGGQMLDYIISHGKLKEKQA 243 Query: 424 RRFFQQIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMR 570 R+F +QI S + Y H+N VVHRDLK EN+L+ D+KI DFGLSN+ R Sbjct: 244 RKFVRQIGSALSYLHQNSVVHRDLKIENILISKTGDIKIIDFGLSNLYR 292
>KKK1_YEAST (P34244) Probable serine/threonine-protein kinase YKL101W (EC| 2.7.11.1) Length = 1518 Score = 135 bits (339), Expect = 1e-31 Identities = 72/182 (39%), Positives = 112/182 (61%), Gaps = 36/182 (19%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRK-----------------------I 231 +++GKTLG GS G+V++A++++TG AIKI+ ++K + Sbjct: 81 WKLGKTLGKGSSGRVRLAKNMETGQLAAIKIVPKKKAFVHCSNNGTVPNSYSSSMVTSNV 140 Query: 232 KNMDMEEK------------VKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGE 375 + + + ++REI I++L H +++ L+EV E +++Y+V+EYV GE Sbjct: 141 SSPSIASREHSNHSQTNPYGIEREIVIMKLISHTNVMALFEVWENKSELYLVLEYVDGGE 200 Query: 376 LFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMVVHRDLKPENLLLD-NNCDVKIADFG 552 LFDY+V KG+L E+EA +F+QI+ GV YCH + HRDLKPENLLLD N +KIADFG Sbjct: 201 LFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIKIADFG 260 Query: 553 LS 558 ++ Sbjct: 261 MA 262
>HUNK_PANTR (Q68UT7) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) Length = 714 Score = 133 bits (335), Expect = 3e-31 Identities = 70/150 (46%), Positives = 103/150 (68%), Gaps = 2/150 (1%) Frame = +1 Query: 118 NYRIG-KTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIK-NMDMEEKVKREIKILRLFM 291 NY IG + LG GSF KV+ H+ TG KVAIK++++++ K + + + ++RE +I ++ Sbjct: 60 NYLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIR 119 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 HP+I +L +++E Y+VME G L I EK RL+E EARR+ +Q+IS V++ HR Sbjct: 120 HPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEHLHR 179 Query: 472 NMVVHRDLKPENLLLDNNCDVKIADFGLSN 561 VVHRDLK ENLLLD + ++K+ DFGLSN Sbjct: 180 AGVVHRDLKIENLLLDEDNNIKLIDFGLSN 209
>HUNK_HUMAN (P57058) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) (Serine/threonine-protein kinase MAK-V) (B19) Length = 714 Score = 133 bits (335), Expect = 3e-31 Identities = 70/150 (46%), Positives = 103/150 (68%), Gaps = 2/150 (1%) Frame = +1 Query: 118 NYRIG-KTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIK-NMDMEEKVKREIKILRLFM 291 NY IG + LG GSF KV+ H+ TG KVAIK++++++ K + + + ++RE +I ++ Sbjct: 60 NYLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIR 119 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 HP+I +L +++E Y+VME G L I EK RL+E EARR+ +Q+IS V++ HR Sbjct: 120 HPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEHLHR 179 Query: 472 NMVVHRDLKPENLLLDNNCDVKIADFGLSN 561 VVHRDLK ENLLLD + ++K+ DFGLSN Sbjct: 180 AGVVHRDLKIENLLLDEDNNIKLIDFGLSN 209
>SNRK_RAT (Q63553) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 746 Score = 133 bits (334), Expect = 4e-31 Identities = 68/164 (41%), Positives = 106/164 (64%), Gaps = 3/164 (1%) Frame = +1 Query: 94 GKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIK 273 G DG Y + KTLG G F VK+A H+ TG KVA+K++++ K+ + + +E++ Sbjct: 7 GYDGKIAGLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLATGH-LFQEVR 65 Query: 274 ILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIV--EKGRLQEQEARRFFQQII 447 ++L HP+I+RLYEVI+ +Y+++E G++FDYI+ E+G L E A+++F QI+ Sbjct: 66 CMKLVQHPNIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEG-LNEDLAKKYFAQIV 124 Query: 448 SGVQYCHRNMVVHRDLKPENLL-LDNNCDVKIADFGLSNVMRDG 576 + YCH+ VVHRDLKPEN++ + VK+ DFG SN + G Sbjct: 125 HAISYCHKLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPG 168
>SNRK_MOUSE (Q8VDU5) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 748 Score = 133 bits (334), Expect = 4e-31 Identities = 68/164 (41%), Positives = 106/164 (64%), Gaps = 3/164 (1%) Frame = +1 Query: 94 GKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIK 273 G DG Y + KTLG G F VK+A H+ TG KVA+K++++ K+ + + +E++ Sbjct: 7 GYDGKIAGLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLATGH-LFQEVR 65 Query: 274 ILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIV--EKGRLQEQEARRFFQQII 447 ++L HP+I+RLYEVI+ +Y+++E G++FDYI+ E+G L E A+++F QI+ Sbjct: 66 CMKLVQHPNIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEG-LNEDLAKKYFAQIV 124 Query: 448 SGVQYCHRNMVVHRDLKPENLL-LDNNCDVKIADFGLSNVMRDG 576 + YCH+ VVHRDLKPEN++ + VK+ DFG SN + G Sbjct: 125 HAISYCHKLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPG 168
>SNRK_HUMAN (Q9NRH2) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 765 Score = 133 bits (334), Expect = 4e-31 Identities = 68/164 (41%), Positives = 106/164 (64%), Gaps = 3/164 (1%) Frame = +1 Query: 94 GKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIK 273 G DG Y + KTLG G F VK+A H+ TG KVA+K++++ K+ + + +E++ Sbjct: 7 GYDGKIAGLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLATGH-LFQEVR 65 Query: 274 ILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIV--EKGRLQEQEARRFFQQII 447 ++L HP+I+RLYEVI+ +Y+++E G++FDYI+ E+G L E A+++F QI+ Sbjct: 66 CMKLVQHPNIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEG-LNEDLAKKYFAQIV 124 Query: 448 SGVQYCHRNMVVHRDLKPENLL-LDNNCDVKIADFGLSNVMRDG 576 + YCH+ VVHRDLKPEN++ + VK+ DFG SN + G Sbjct: 125 HAISYCHKLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPG 168
>HUNK_MOUSE (O88866) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) (Serine/threonine-protein kinase MAK-V) Length = 714 Score = 132 bits (332), Expect = 7e-31 Identities = 70/150 (46%), Positives = 102/150 (68%), Gaps = 2/150 (1%) Frame = +1 Query: 118 NYRIG-KTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIK-NMDMEEKVKREIKILRLFM 291 NY IG + LG GSF KV+ H+ TG KVAIK++++++ K + + + ++RE +I ++ Sbjct: 60 NYLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIR 119 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 HP+I +L +++E Y+VME G L I EK RL E EARR+ +Q+IS V++ HR Sbjct: 120 HPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLDEAEARRYIRQLISAVEHLHR 179 Query: 472 NMVVHRDLKPENLLLDNNCDVKIADFGLSN 561 VVHRDLK ENLLLD + ++K+ DFGLSN Sbjct: 180 AGVVHRDLKIENLLLDEDNNIKLIDFGLSN 209
>SAPK1_ORYSA (Q75LR7) Serine/threonine-protein kinase SAPK1 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 1) Length = 342 Score = 129 bits (325), Expect = 5e-30 Identities = 68/151 (45%), Positives = 90/151 (59%), Gaps = 2/151 (1%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 ++ Y + + +G G+FG K+ + T H A+K + R + ++E V+REI R Sbjct: 1 MERYEVMRDIGSGNFGVAKLVRDVATNHLFAVKFIER----GLKIDEHVQREIMNHRSLK 56 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 HP+IIR EV+ P + +VMEY GELF+ I GR E EAR FFQQ+ISGV YCH Sbjct: 57 HPNIIRFKEVVLTPTHLAIVMEYAAGGELFERICNAGRFSEDEARFFFQQLISGVSYCHS 116 Query: 472 NMVVHRDLKPENLLLDNNCD--VKIADFGLS 558 V HRDLK EN LLD + +KI DFG S Sbjct: 117 MQVCHRDLKLENTLLDGSVTPRLKICDFGYS 147
>MYLK_DICDI (P25323) Myosin light chain kinase (EC 2.7.11.18) (MLCK)| Length = 295 Score = 128 bits (322), Expect = 1e-29 Identities = 69/154 (44%), Positives = 99/154 (64%), Gaps = 3/154 (1%) Frame = +1 Query: 115 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 294 K Y + LG G+F V + E+ +T + AIK++N+ ++ D E+ +K E+ IL+ H Sbjct: 6 KIYEFKEELGRGAFSIVYLGENKQTKQRYAIKVINKSEL-GKDYEKNLKMEVDILKKVNH 64 Query: 295 PHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRN 474 P+II L E+ + P +Y+VME V GELFD IVEKG E +A ++I+S V Y H Sbjct: 65 PNIIALKELFDTPEKLYLVMELVTGGELFDKIVEKGSYSEADAANLVKKIVSAVGYLHGL 124 Query: 475 MVVHRDLKPENLLL---DNNCDVKIADFGLSNVM 567 +VHRDLKPENLLL +N+ +V IADFGLS ++ Sbjct: 125 NIVHRDLKPENLLLKSKENHLEVAIADFGLSKII 158
>CDS1_SCHPO (Q09170) Serine/threonine-protein kinase cds1 (EC 2.7.11.1)| (Checkpoint kinase cds1) Length = 460 Score = 128 bits (322), Expect = 1e-29 Identities = 62/161 (38%), Positives = 105/161 (65%), Gaps = 5/161 (3%) Frame = +1 Query: 118 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKV----KREIKILRL 285 +Y I +TLG G+F VK+A + +G AIKI+N+RKI E++ +REI IL+ Sbjct: 166 HYEIIRTLGSGTFAVVKLAVEVNSGKWYAIKIINKRKILLTSSEKRATEMFQREIDILKS 225 Query: 286 FMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYC 465 HP +++ +E+ E ++++VMEYV+ G+L D+++ G + EQ+ + +Q++ + + Sbjct: 226 LHHPGVVQCHEIFENDDELFIVMEYVEGGDLMDFLIANGSIDEQDCKPLLKQLLETLLHL 285 Query: 466 HRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMR-DGHFL 585 H+ V HRD+KPEN+L+ N+ +KI+DFGL+ V+ G FL Sbjct: 286 HKQGVTHRDIKPENILITNDFHLKISDFGLAKVIHGTGTFL 326
>CHK2_MOUSE (Q9Z265) Serine/threonine-protein kinase Chk2 (EC 2.7.11.1)| Length = 546 Score = 126 bits (317), Expect = 4e-29 Identities = 68/157 (43%), Positives = 102/157 (64%), Gaps = 8/157 (5%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKI-----KNMDMEEKVKREIKILRL 285 Y + KTLG G+ G+VK+A KT KVAIKI+++R+ + D V+ EI+IL+ Sbjct: 224 YIMSKTLGSGACGEVKMAFERKTCQKVAIKIISKRRFALGSSREADTAPSVETEIEILKK 283 Query: 286 FMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYC 465 HP II++ +V +A D Y+V+E ++ GELFD +V RL+E + +F Q++ VQY Sbjct: 284 LNHPCIIKIKDVFDAE-DYYIVLELMEGGELFDRVVGNKRLKEATCKLYFYQMLVAVQYL 342 Query: 466 HRNMVVHRDLKPENLLL---DNNCDVKIADFGLSNVM 567 H N ++HRDLKPEN+LL + +C +KI DFG S ++ Sbjct: 343 HENGIIHRDLKPENVLLSSQEEDCLIKITDFGQSKIL 379
>SAPK2_ORYSA (Q84TC6) Serine/threonine-protein kinase SAPK2 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 2) Length = 339 Score = 126 bits (316), Expect = 5e-29 Identities = 66/151 (43%), Positives = 89/151 (58%), Gaps = 2/151 (1%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 ++ Y + K +G G+FG K+ ++T A+K + R ++E V+REI R Sbjct: 1 MERYEVIKDIGSGNFGVAKLVRDVRTKELFAVKFIER----GQKIDENVQREIMNHRSLR 56 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 HP+I+R EV+ P + +VMEY GELF+ I GR E EAR FFQQ+ISGV YCH Sbjct: 57 HPNIVRFKEVVLTPTHLAIVMEYAAGGELFERICSAGRFSEDEARFFFQQLISGVSYCHS 116 Query: 472 NMVVHRDLKPENLLLDNNC--DVKIADFGLS 558 + HRDLK EN LLD + +KI DFG S Sbjct: 117 MQICHRDLKLENTLLDGSIAPRLKICDFGYS 147
>CDPK4_PLAF7 (Q8IBS5) Calcium-dependent protein kinase 4 (EC 2.7.11.1)| Length = 527 Score = 125 bits (315), Expect = 7e-29 Identities = 64/152 (42%), Positives = 99/152 (65%), Gaps = 4/152 (2%) Frame = +1 Query: 115 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 294 + Y+ K LG GSFG+V ++ TGH+ AIK+++++ +K +E + RE+++L++ H Sbjct: 67 EQYKGIKILGKGSFGEVILSRDKHTGHEYAIKVISKKHVKRKTDKESLLREVELLKMLDH 126 Query: 295 PHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRN 474 +I++LYE E Y+V + GELFD I+ + R E +A R +QI+SG+ Y H+N Sbjct: 127 INIMKLYEFFEDNNYYYLVSDVYTGGELFDEIISRKRFYEIDAARIIKQILSGITYMHKN 186 Query: 475 MVVHRDLKPENLLLD----NNCDVKIADFGLS 558 VVHRDLKPEN+LL+ + +KI DFGLS Sbjct: 187 NVVHRDLKPENILLETKNKEDMIIKIIDFGLS 218
>CDPK4_PLAYO (Q7RJG2) Calcium-dependent protein kinase 4 (EC 2.7.11.1)| Length = 527 Score = 125 bits (314), Expect = 9e-29 Identities = 62/152 (40%), Positives = 100/152 (65%), Gaps = 4/152 (2%) Frame = +1 Query: 115 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 294 + Y+ K LG GSFG+V +++ TGH+ AIK+++++ +K ++ + RE+++L++ H Sbjct: 67 EQYKGIKILGKGSFGEVILSKDKHTGHEYAIKVISKKHVKRKTDKQSLLREVELLKMLDH 126 Query: 295 PHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRN 474 +I++LYE E Y+V + GELFD I+ + R E +A R +Q++SG+ Y H+N Sbjct: 127 INIMKLYEFFEDNNYYYLVSDVYSGGELFDEIISRKRFYEVDAARIIKQVLSGITYMHKN 186 Query: 475 MVVHRDLKPENLLLD----NNCDVKIADFGLS 558 VVHRDLKPEN+LL+ + +KI DFGLS Sbjct: 187 NVVHRDLKPENILLETKNKEDMIIKIIDFGLS 218
>CDPK4_PLABA (P62345) Calcium-dependent protein kinase 4 (EC 2.7.11.1) (PbCDPK4)| Length = 527 Score = 125 bits (314), Expect = 9e-29 Identities = 62/152 (40%), Positives = 100/152 (65%), Gaps = 4/152 (2%) Frame = +1 Query: 115 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 294 + Y+ K LG GSFG+V +++ TGH+ AIK+++++ +K ++ + RE+++L++ H Sbjct: 67 EQYKGIKILGKGSFGEVILSKDKHTGHEYAIKVISKKHVKRKTDKQSLLREVELLKMLDH 126 Query: 295 PHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRN 474 +I++LYE E Y+V + GELFD I+ + R E +A R +Q++SG+ Y H+N Sbjct: 127 INIMKLYEFFEDNNYYYLVSDVYSGGELFDEIISRKRFYEVDAARIIKQVLSGITYMHKN 186 Query: 475 MVVHRDLKPENLLLD----NNCDVKIADFGLS 558 VVHRDLKPEN+LL+ + +KI DFGLS Sbjct: 187 NVVHRDLKPENILLETKNKEDMIIKIIDFGLS 218
>CDR2_SCHPO (P87050) Mitosis inducer protein kinase cdr2 (EC 2.7.11.1)| Length = 775 Score = 124 bits (312), Expect = 2e-28 Identities = 56/155 (36%), Positives = 97/155 (62%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 + +G +LG G ++A+H +TG +K + + +++ E+ +LRL HP+ Sbjct: 10 WELGLSLGSGGPNSSRLAKHRETGQLAVVKPIVGWSELTSSQQARIEGELVLLRLIEHPN 69 Query: 301 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 480 +++L +VI A ++VV+EY+ GELFD ++ KG EQ+ +F QI+ G++YCH+ + Sbjct: 70 VLQLIDVISAQEQLFVVVEYMPGGELFDCMLRKGSFTEQDTAKFLWQILCGLEYCHKLHI 129 Query: 481 VHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFL 585 HRDLKPENL LD + +KI +FG++++ + G L Sbjct: 130 CHRDLKPENLYLDAHGSIKIGEFGMASIQQPGKLL 164
>SAPK9_ORYSA (Q75V57) Serine/threonine-protein kinase SAPK9 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 9) Length = 361 Score = 124 bits (311), Expect = 2e-28 Identities = 69/148 (46%), Positives = 90/148 (60%), Gaps = 2/148 (1%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 Y + K +G G+FG ++ + +G VA+K ++R + ++E V+REI R HP+ Sbjct: 22 YELVKEIGSGNFGVARLMRNRASGDLVAVKYIDRGE----KIDENVQREIINHRSLRHPN 77 Query: 301 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 480 IIR EVI P + +VMEY GELF+ I GR E EAR FFQQ+ISGV YCH V Sbjct: 78 IIRFKEVILTPTHLAIVMEYASGGELFERICSAGRFSEDEARFFFQQLISGVSYCHSMQV 137 Query: 481 VHRDLKPENLLLDNNC--DVKIADFGLS 558 HRDLK EN LLD + +KI DFG S Sbjct: 138 CHRDLKLENTLLDGSTAPRLKICDFGYS 165
>ASK2_ARATH (P43292) Serine/threonine-protein kinase ASK2 (EC 2.7.11.1)| Length = 353 Score = 123 bits (309), Expect = 3e-28 Identities = 73/152 (48%), Positives = 88/152 (57%), Gaps = 3/152 (1%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNR-RKIKNMDMEEKVKREIKILRLF 288 + Y + K LG G+FG ++ H T VA+K + R RKI +E V REI R Sbjct: 1 MDKYDVVKDLGAGNFGVARLLRHKDTKELVAMKYIERGRKI-----DENVAREIINHRSL 55 Query: 289 MHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCH 468 HP+IIR EVI P + +VMEY GELFD I GR E EAR FFQQ+I GV YCH Sbjct: 56 KHPNIIRFKEVILTPTHLAIVMEYASGGELFDRICTAGRFSEAEARYFFQQLICGVDYCH 115 Query: 469 RNMVVHRDLKPENLLLDNNCD--VKIADFGLS 558 + HRDLK EN LLD + +KI DFG S Sbjct: 116 SLQICHRDLKLENTLLDGSPAPLLKICDFGYS 147
>TSSK1_MOUSE (Q61241) Testis-specific serine/threonine-protein kinase 1 (EC| 2.7.11.1) (TSSK-1) (Testis-specific kinase 1) (TSK-1) (Serine/threonine-protein kinase 22A) Length = 364 Score = 123 bits (309), Expect = 3e-28 Identities = 63/149 (42%), Positives = 97/149 (65%), Gaps = 1/149 (0%) Frame = +1 Query: 115 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 294 + Y +G LG GS+ KVK A + VA+KI++R+K + +E+ + REI+IL + H Sbjct: 10 RGYIMGINLGEGSYAKVKSAYSERLKFNVAVKIIDRKKAPSDFLEKFLPREIEILAMLNH 69 Query: 295 PHIIRLYEVIE-APADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 I++ YE+ + +Y+VME G+L ++I +G LQE +AR+ F Q+ S ++YCH Sbjct: 70 RSIVKTYEIFATSDGKVYIVMELGVQGDLLEFIKTRGALQEDDARKKFHQLSSAIKYCHD 129 Query: 472 NMVVHRDLKPENLLLDNNCDVKIADFGLS 558 VVHRDLK ENLLLD + ++K++DFG S Sbjct: 130 LDVVHRDLKSENLLLDKDFNIKLSDFGFS 158
>CHK2_HUMAN (O96017) Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (Cds1)| Length = 543 Score = 123 bits (309), Expect = 3e-28 Identities = 68/157 (43%), Positives = 100/157 (63%), Gaps = 8/157 (5%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKI-----KNMDMEEKVKREIKILRL 285 Y + KTLG G+ G+VK+A KT KVAIKI+++RK + D V+ EI+IL+ Sbjct: 220 YIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILKK 279 Query: 286 FMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYC 465 HP II++ +A D Y+V+E ++ GELFD +V RL+E + +F Q++ VQY Sbjct: 280 LNHPCIIKIKNFFDAE-DYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQYL 338 Query: 466 HRNMVVHRDLKPENLLL---DNNCDVKIADFGLSNVM 567 H N ++HRDLKPEN+LL + +C +KI DFG S ++ Sbjct: 339 HENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKIL 375
>CDR1_SCHPO (P07334) Mitosis inducer protein kinase cdr1 (EC 2.7.11.1) (Protein| kinase nim1) Length = 593 Score = 123 bits (308), Expect = 4e-28 Identities = 68/154 (44%), Positives = 94/154 (61%), Gaps = 1/154 (0%) Frame = +1 Query: 106 NPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRL 285 N + +R+GKTLG GS V++A+H KTG AIKI+ R + EI ++RL Sbjct: 7 NTIGVWRLGKTLGTGSTSCVRLAKHAKTGDLAAIKIIPIRYAS-------IGMEILMMRL 59 Query: 286 FMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYC 465 HP+I+RLY+V +Y+ +EYV GELF YI + G L E+EA + QI+ V +C Sbjct: 60 LRHPNILRLYDVWTDHQHMYLALEYVPDGELFHYIRKHGPLSEREAAHYLSQILDAVAHC 119 Query: 466 HRNMVVHRDLKPENLLLD-NNCDVKIADFGLSNV 564 HR HRDLK EN+L+ N +KIADFG++ V Sbjct: 120 HRFRFRHRDLKLENILIKVNEQQIKIADFGMATV 153
>CHK1_XENLA (Q6DE87) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (xChk1| protein) Length = 474 Score = 123 bits (308), Expect = 4e-28 Identities = 64/153 (41%), Positives = 100/153 (65%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 ++++ + +TLG G++G+V++A + KT VA+KI++ + D E +K+EI I R+ Sbjct: 6 VEDWDLVQTLGEGAYGEVQLAVNRKTEEAVAVKIVDMTRAA--DCPENIKKEICINRMLS 63 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 H +I+R Y Y+ +EY + GELFD I + EQ+A++FFQQ+I+GV+Y H Sbjct: 64 HTNIVRFYGHRREGNIQYLFLEYCRGGELFDRIEPDVGMPEQDAQKFFQQLIAGVEYLHS 123 Query: 472 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMR 570 + HRD+KPENLLLD +KI+DFGL+ V R Sbjct: 124 IGITHRDIKPENLLLDERDQLKISDFGLATVFR 156
>KIN4_YEAST (Q01919) Serine/threonine-protein kinase KIN4 (EC 2.7.11.1)| Length = 800 Score = 122 bits (307), Expect = 6e-28 Identities = 72/153 (47%), Positives = 94/153 (61%), Gaps = 6/153 (3%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKI-----AEHIKTGHKVAIKILNRRKIK-NMDMEEKVKREIKILR 282 Y IG TLG G FGKVK+ + + +VAIK++ R IK + D E K+ REI L+ Sbjct: 46 YIIGSTLGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKKDADKEIKIYREINALK 105 Query: 283 LFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQY 462 HP+II L EV++ I +V+E+V GE + YI K RL+E A R F Q+ISGV Y Sbjct: 106 HLTHPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKRRLKESSACRLFAQLISGVNY 165 Query: 463 CHRNMVVHRDLKPENLLLDNNCDVKIADFGLSN 561 H +VHRDLK ENLLLD + ++ I DFG N Sbjct: 166 MHYKGLVHRDLKLENLLLDKHENLVITDFGFVN 198
>DAPK2_MOUSE (Q8VDF3) Death-associated protein kinase 2 (EC 2.7.11.1) (DAP| kinase 2) (DAP-kinase-related protein 1) (DRP-1) Length = 370 Score = 122 bits (306), Expect = 8e-28 Identities = 65/159 (40%), Positives = 96/159 (60%), Gaps = 7/159 (4%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDM---EEKVKREIKILRLFM 291 Y IG+ LG G F VK TG + A K + +R+ + E+++RE+ ILR + Sbjct: 23 YDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVCREEIEREVSILRQVL 82 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 HP+II L++V E D+ +++E V GELFD++ +K L E+EA F +QI+ GV Y H Sbjct: 83 HPNIITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHT 142 Query: 472 NMVVHRDLKPEN-LLLDNNC---DVKIADFGLSNVMRDG 576 + H DLKPEN +LLD N +K+ DFGL++ + DG Sbjct: 143 KKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDG 181
>KIN1_YEAST (P13185) Protein kinase KIN1 (EC 2.7.11.1)| Length = 1064 Score = 122 bits (305), Expect = 1e-27 Identities = 63/177 (35%), Positives = 102/177 (57%), Gaps = 26/177 (14%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNR----------------------- 222 L ++ +T+G GS GKVK+A+H T A+KI+NR Sbjct: 117 LGDWEFVETVGAGSMGKVKLAKHRYTNEVCAVKIVNRATKAFLHKEQMLPPPKNEQDVLE 176 Query: 223 --RKI-KNMDMEEKVKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIV 393 +K+ K + +++ RE + ++ HPHI RL+E+ Y++ EYV G+L DYI+ Sbjct: 177 RQKKLEKEISRDKRTIREASLGQILYHPHICRLFEMCTLSNHFYMLFEYVSGGQLLDYII 236 Query: 394 EKGRLQEQEARRFFQQIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNV 564 + G ++E +AR+F + I S + Y H N +VHRDLK EN+++ ++ ++KI DFGLSN+ Sbjct: 237 QHGSIREHQARKFARGIASALIYLHANNIVHRDLKIENIMISDSSEIKIIDFGLSNI 293
>KIN2_YEAST (P13186) Serine/threonine-protein kinase KIN2 (EC 2.7.11.1)| Length = 1147 Score = 121 bits (304), Expect = 1e-27 Identities = 64/177 (36%), Positives = 99/177 (55%), Gaps = 26/177 (14%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNR----------------------- 222 L ++ +T+G GS GKVK+ +H +T IKI+NR Sbjct: 96 LGDWEFLETVGAGSMGKVKLVKHRQTKEICVIKIVNRASKAYLHKQHSLPSPKNESEILE 155 Query: 223 ---RKIKNMDMEEKVKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIV 393 R K + +++ RE + ++ HPHI RL+E+ Y++ EYV G+L DYI+ Sbjct: 156 RQKRLEKEIARDKRTVREASLGQILYHPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYII 215 Query: 394 EKGRLQEQEARRFFQQIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNV 564 + G L+E AR+F + I S +QY H N +VHRDLK EN+++ ++ ++KI DFGLSN+ Sbjct: 216 QHGSLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSSGEIKIIDFGLSNI 272
>SAPK7_ORYSA (Q7XQP4) Serine/threonine-protein kinase SAPK7 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 7) Length = 359 Score = 121 bits (303), Expect = 2e-27 Identities = 67/151 (44%), Positives = 89/151 (58%), Gaps = 2/151 (1%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 ++ Y + K +G G+FG ++ + +T VA+K + R + ++E V REI R Sbjct: 1 MERYELLKDIGAGNFGVARLMRNKETKELVAMKYIPR----GLKIDENVAREIINHRSLR 56 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 HP+IIR EV+ P + +VMEY GELFD I GR E EAR FFQQ+I GV YCH Sbjct: 57 HPNIIRFKEVVVTPTHLAIVMEYAAGGELFDRICNAGRFSEDEARYFFQQLICGVSYCHF 116 Query: 472 NMVVHRDLKPENLLLDNN--CDVKIADFGLS 558 + HRDLK EN LLD + +KI DFG S Sbjct: 117 MQICHRDLKLENTLLDGSPAPRLKICDFGYS 147
>CHK1_CHICK (Q8AYC9) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 120 bits (302), Expect = 2e-27 Identities = 62/153 (40%), Positives = 100/153 (65%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 ++++ + +TLG G++G+V++A + +T VA+KI++ ++ D E +K+EI I ++ Sbjct: 6 VEDWDLVQTLGEGAYGEVQLAVNRRTEEAVAVKIVDMKRAA--DCPENIKKEICINKMLN 63 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 H ++++ Y A Y+ +EY GELFD I + E EA+RFFQQ+I+GV Y H Sbjct: 64 HENVVKFYGHRREGATQYLFLEYCSGGELFDRIEPDIGMPEPEAQRFFQQLIAGVVYLHS 123 Query: 472 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMR 570 + HRDLKPENLLLD ++KI+DFGL+ V + Sbjct: 124 MGITHRDLKPENLLLDERDNLKISDFGLATVFK 156
>SAPK3_ORYSA (Q75V63) Serine/threonine-protein kinase SAPK3 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 3) (Protein kinase REK) Length = 334 Score = 120 bits (302), Expect = 2e-27 Identities = 69/150 (46%), Positives = 87/150 (58%), Gaps = 2/150 (1%) Frame = +1 Query: 115 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 294 + Y K LG G+FG ++ ++ VA+K + R K ++E V+REI R H Sbjct: 3 ERYEALKELGAGNFGVARLVRDKRSKELVAVKYIERGK----KIDENVQREIINHRSLRH 58 Query: 295 PHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRN 474 P+IIR EV P + +VMEY GELF+ I GR E EAR FFQQ+ISGV YCH Sbjct: 59 PNIIRFKEVCLTPTHLAIVMEYAAGGELFEQICTAGRFSEDEARYFFQQLISGVSYCHSL 118 Query: 475 MVVHRDLKPENLLLDNNCD--VKIADFGLS 558 + HRDLK EN LLD + VKI DFG S Sbjct: 119 EICHRDLKLENTLLDGSPTPRVKICDFGYS 148
>KCC1D_MOUSE (Q8BW96) Calcium/calmodulin-dependent protein kinase type 1D (EC| 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) (mCKLiK) Length = 385 Score = 120 bits (302), Expect = 2e-27 Identities = 64/157 (40%), Positives = 94/157 (59%), Gaps = 3/157 (1%) Frame = +1 Query: 115 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 294 K + +TLG G+F +V +AE TG A+K + ++ +K E ++ EI +LR H Sbjct: 21 KIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGK--ESSIENEIAVLRKIKH 78 Query: 295 PHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRN 474 +I+ L ++ E+P +Y+VM+ V GELFD IVEKG E++A +Q++ V Y HR Sbjct: 79 ENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRM 138 Query: 475 MVVHRDLKPENLLL---DNNCDVKIADFGLSNVMRDG 576 +VHRDLKPENLL D + I+DFGLS + G Sbjct: 139 GIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKG 175
>KCC1D_HUMAN (Q8IU85) Calcium/calmodulin-dependent protein kinase type 1D (EC| 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) Length = 385 Score = 120 bits (302), Expect = 2e-27 Identities = 64/157 (40%), Positives = 94/157 (59%), Gaps = 3/157 (1%) Frame = +1 Query: 115 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 294 K + +TLG G+F +V +AE TG A+K + ++ +K E ++ EI +LR H Sbjct: 21 KIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGK--ESSIENEIAVLRKIKH 78 Query: 295 PHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRN 474 +I+ L ++ E+P +Y+VM+ V GELFD IVEKG E++A +Q++ V Y HR Sbjct: 79 ENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRM 138 Query: 475 MVVHRDLKPENLLL---DNNCDVKIADFGLSNVMRDG 576 +VHRDLKPENLL D + I+DFGLS + G Sbjct: 139 GIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKG 175
>SAPK4_ORYSA (Q5N942) Serine/threonine-protein kinase SAPK4 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 4) Length = 360 Score = 120 bits (302), Expect = 2e-27 Identities = 66/151 (43%), Positives = 90/151 (59%), Gaps = 2/151 (1%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 ++ Y + +G G+FG ++ + +T VA+K + R ++E V REI R Sbjct: 1 MEKYEAVRDIGSGNFGVARLMRNRETRELVAVKCIER----GHRIDENVYREIINHRSLR 56 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 HP+IIR EVI P + +VME+ GELFD I ++GR E EAR FFQQ+I GV YCH Sbjct: 57 HPNIIRFKEVILTPTHLMIVMEFAAGGELFDRICDRGRFSEDEARYFFQQLICGVSYCHH 116 Query: 472 NMVVHRDLKPENLLLDNN--CDVKIADFGLS 558 + HRDLK EN+LLD + +KI DFG S Sbjct: 117 MQICHRDLKLENVLLDGSPAPRLKICDFGYS 147
>SAPKA_ORYSA (Q75H77) Serine/threonine-protein kinase SAPK10 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 10) Length = 362 Score = 120 bits (302), Expect = 2e-27 Identities = 68/148 (45%), Positives = 86/148 (58%), Gaps = 2/148 (1%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 Y + + +G G+FG ++ G VA+K + R ++E V+REI R HP+ Sbjct: 23 YELVRDIGSGNFGVARLMRSRADGQLVAVKYIERGD----KIDENVQREIINHRSLRHPN 78 Query: 301 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 480 IIR EVI P + +VMEY GELF+ I GR E EAR FFQQ+ISGV YCH V Sbjct: 79 IIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLISGVSYCHSMQV 138 Query: 481 VHRDLKPENLLLDNNC--DVKIADFGLS 558 HRDLK EN LLD + +KI DFG S Sbjct: 139 CHRDLKLENTLLDGSTAPRLKICDFGYS 166
>STK6_XENLA (Q91820) Serine/threonine-protein kinase Eg2 (EC 2.7.11.1) (pEg2)| (p46Eg265) Length = 407 Score = 120 bits (301), Expect = 3e-27 Identities = 57/158 (36%), Positives = 98/158 (62%) Frame = +1 Query: 85 EAGGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKR 264 E G K L+++ IG+ LG G FG V +A ++ +A+K+L + +++ +E +++R Sbjct: 128 EEGKKKQWCLEDFEIGRPLGKGKFGNVYLARERESKFILALKVLFKSQLEKAGVEHQLRR 187 Query: 265 EIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQI 444 E++I HP+I+RLY + +Y++++Y GELF + + R +Q + + +Q+ Sbjct: 188 EVEIQSHLRHPNILRLYGYFHDASRVYLILDYAPGGELFRELQKCTRFDDQRSAMYIKQL 247 Query: 445 ISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLS 558 + YCH V+HRD+KPENLLL +N ++KIADFG S Sbjct: 248 AEALLYCHSKKVIHRDIKPENLLLGSNGELKIADFGWS 285
>KCC1_YEAST (P27466) Calcium/calmodulin-dependent protein kinase I (EC| 2.7.11.17) Length = 446 Score = 120 bits (301), Expect = 3e-27 Identities = 62/156 (39%), Positives = 99/156 (63%), Gaps = 4/156 (2%) Frame = +1 Query: 115 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDME-EKVKREIKILRLFM 291 K Y GKTLG G+FG V+ A++ +TG VA+KIL ++ +K ++ E + E+ IL+ Sbjct: 35 KKYVFGKTLGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLH 94 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 HP+I+ + E+ Y++ + K GELFD I++KG+ E++A R +I+S V+Y H Sbjct: 95 HPNIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVRILVEILSAVKYMHS 154 Query: 472 NMVVHRDLKPENLLLDNNCD---VKIADFGLSNVMR 570 +VHRDLKPENLL + D + +ADFG++ ++ Sbjct: 155 QNIVHRDLKPENLLYIDKSDESPLVVADFGIAKRLK 190
>DAPK1_MOUSE (Q80YE7) Death-associated protein kinase 1 (EC 2.7.11.1) (DAP| kinase 1) Length = 1442 Score = 120 bits (300), Expect = 4e-27 Identities = 66/160 (41%), Positives = 95/160 (59%), Gaps = 7/160 (4%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDM---EEKVKREIKILRLFM 291 Y G+ LG G F VK TG + A K + +R+ K+ E ++RE+ IL+ Sbjct: 13 YDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIEREVSILKEIR 72 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 HP++I L+EV E D+ +++E V GELFD++ EK L E+EA F +QI+SGV Y H Sbjct: 73 HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILSGVYYLHS 132 Query: 472 NMVVHRDLKPEN-LLLDNNCD---VKIADFGLSNVMRDGH 579 + H DLKPEN +LLD N +KI DFGL++ + G+ Sbjct: 133 LQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGN 172
>AURKB_RAT (O55099) Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-| and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora-B) Length = 343 Score = 120 bits (300), Expect = 4e-27 Identities = 58/149 (38%), Positives = 90/149 (60%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 + N+ IG+ LG G FG V +A K+ VA+KIL + +I+ +E +++REI+I Sbjct: 77 IDNFEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQIEKEGVEHQLRREIEIQAHLK 136 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 HP+I++LY IY+++EY GEL+ + + G EQ +++ + YCH+ Sbjct: 137 HPNILQLYNYFYDQQRIYLILEYAPRGELYKELQKSGTFDEQRTATIMEELSDALMYCHK 196 Query: 472 NMVVHRDLKPENLLLDNNCDVKIADFGLS 558 V+HRD+KPENLLL ++KIADFG S Sbjct: 197 KKVIHRDIKPENLLLGLQGELKIADFGWS 225
>STK6L_XENLA (Q91819) Serine/threonine-protein kinase Eg2-like (EC 2.7.11.1)| (p46XlEg22) Length = 408 Score = 120 bits (300), Expect = 4e-27 Identities = 57/158 (36%), Positives = 98/158 (62%) Frame = +1 Query: 85 EAGGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKR 264 E G K L+++ IG+ LG G FG V +A ++ +A+K+L + +++ +E +++R Sbjct: 128 EEGKKKQWCLEDFEIGRPLGKGKFGNVYLARERESKFILALKVLFKSQLEKAGVEHQLRR 187 Query: 265 EIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQI 444 E++I HP+I+RLY + +Y++++Y GELF + + R +Q + + +Q+ Sbjct: 188 EVEIQSHLRHPNILRLYGYFHDASRVYLILDYAPGGELFRELQKCTRFDDQRSALYIKQL 247 Query: 445 ISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLS 558 + YCH V+HRD+KPENLLL +N ++KIADFG S Sbjct: 248 AEALLYCHSKKVIHRDIKPENLLLGSNGELKIADFGWS 285
>DAPK3_HUMAN (O43293) Death-associated protein kinase 3 (EC 2.7.11.1) (DAP| kinase 3) (DAP-like kinase) (Dlk) (ZIP-kinase) Length = 454 Score = 120 bits (300), Expect = 4e-27 Identities = 61/161 (37%), Positives = 97/161 (60%), Gaps = 7/161 (4%) Frame = +1 Query: 118 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDM---EEKVKREIKILRLF 288 +Y +G+ LG G F V+ TG + A K + +R++ + E+++RE+ ILR Sbjct: 12 HYEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREI 71 Query: 289 MHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCH 468 HP+II L+++ E D+ +++E V GELFD++ EK L E EA +F +QI+ GV Y H Sbjct: 72 RHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLH 131 Query: 469 RNMVVHRDLKPEN-LLLDNNCD---VKIADFGLSNVMRDGH 579 + H DLKPEN +LLD N +K+ DFG+++ + G+ Sbjct: 132 SKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGN 172
>YP141_YEAST (Q03002) Putative serine/threonine-protein kinase YPL141C (EC| 2.7.11.1) Length = 865 Score = 119 bits (299), Expect = 5e-27 Identities = 70/158 (44%), Positives = 92/158 (58%), Gaps = 11/158 (6%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIA----------EHIKTGHKVAIKILNRRKIKNMDMEE-KVKRE 267 Y +G TLG G FGKVK+ +VAIK++ R I N +E K+ RE Sbjct: 41 YILGSTLGEGEFGKVKLGWPKNFSNSSNSTFDFPKQVAIKLIKRDSISNDYRKEVKIYRE 100 Query: 268 IKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQII 447 I L+ HP+I++L EV++ I +V+EY GE + YI +K RL+E A R F Q+I Sbjct: 101 INALKHLSHPNIVKLEEVLQNSRYIGIVLEYACGGEFYKYIQKKRRLKEMNACRLFSQLI 160 Query: 448 SGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSN 561 SGV Y H +VHRDLK ENLLLD N ++ I DFG N Sbjct: 161 SGVHYIHSKGLVHRDLKLENLLLDKNENLVITDFGFVN 198
>PLK4_HUMAN (O00444) Serine/threonine-protein kinase PLK4 (EC 2.7.11.21)| (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine-protein kinase 18) Length = 970 Score = 119 bits (299), Expect = 5e-27 Identities = 62/160 (38%), Positives = 98/160 (61%), Gaps = 1/160 (0%) Frame = +1 Query: 103 GNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILR 282 G ++++++G LG GSF V AE I TG +VAIK+++++ + M ++V+ E+KI Sbjct: 6 GEKIEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHC 65 Query: 283 LFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGR-LQEQEARRFFQQIISGVQ 459 HP I+ LY E +Y+V+E +GE+ Y+ + + E EAR F QII+G+ Sbjct: 66 QLKHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGML 125 Query: 460 YCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGH 579 Y H + ++HRDL NLLL N ++KIADFGL+ ++ H Sbjct: 126 YLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPH 165
>TSSK2_HUMAN (Q96PF2) Testis-specific serine/threonine-protein kinase 2 (EC| 2.7.11.1) (TSSK-2) (Testis-specific kinase 2) (TSK-2) (Serine/threonine-protein kinase 22B) (DiGeorge syndrome protein G) Length = 358 Score = 119 bits (298), Expect = 6e-27 Identities = 66/157 (42%), Positives = 97/157 (61%), Gaps = 2/157 (1%) Frame = +1 Query: 115 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 294 K Y +G LG GS+ KVK A + VA+KI++R+K +E + RE+ IL H Sbjct: 10 KGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNH 69 Query: 295 PHIIRLYEVIE-APADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 II+ YE+ E + IY++ME G+L ++I +G L E AR+ F+Q+ S V+YCH Sbjct: 70 GSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQLSSAVKYCHD 129 Query: 472 NMVVHRDLKPENLLLDNNCDVKIADFGLS-NVMRDGH 579 +VHRDLK ENLLLD + ++K++DFG S +RD + Sbjct: 130 LDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSN 166
>DAPK1_HUMAN (P53355) Death-associated protein kinase 1 (EC 2.7.11.1) (DAP| kinase 1) Length = 1432 Score = 119 bits (298), Expect = 6e-27 Identities = 65/160 (40%), Positives = 95/160 (59%), Gaps = 7/160 (4%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDM---EEKVKREIKILRLFM 291 Y G+ LG G F VK TG + A K + +R+ K+ E ++RE+ IL+ Sbjct: 13 YDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIEREVSILKEIQ 72 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 HP++I L+EV E D+ +++E V GELFD++ EK L E+EA F +QI++GV Y H Sbjct: 73 HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGVYYLHS 132 Query: 472 NMVVHRDLKPEN-LLLDNNCD---VKIADFGLSNVMRDGH 579 + H DLKPEN +LLD N +KI DFGL++ + G+ Sbjct: 133 LQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGN 172
>SAPK6_ORYSA (Q6ZI44) Serine/threonine-protein kinase SAPK6 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 6) Length = 365 Score = 119 bits (298), Expect = 6e-27 Identities = 66/151 (43%), Positives = 89/151 (58%), Gaps = 2/151 (1%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 ++ Y + K +G G+FG ++ + +T VA+K + R + ++E V REI R Sbjct: 1 MEKYELLKDIGSGNFGVARLMRNRETKELVAMKYIPR----GLKIDENVAREIINHRSLR 56 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 HP+IIR EV+ P + +VMEY GELFD I GR E E+R FFQQ+I GV YCH Sbjct: 57 HPNIIRFKEVVLTPTHLAIVMEYAAGGELFDRICSAGRFSEDESRYFFQQLICGVSYCHF 116 Query: 472 NMVVHRDLKPENLLLDNN--CDVKIADFGLS 558 + HRDLK EN LLD + +KI DFG S Sbjct: 117 MQICHRDLKLENTLLDGSPAPRLKICDFGYS 147
>AAIP_WHEAT (Q02066) Abscisic acid-inducible protein kinase (EC 2.7.11.1)| (Fragment) Length = 332 Score = 118 bits (296), Expect = 1e-26 Identities = 65/141 (46%), Positives = 81/141 (57%), Gaps = 2/141 (1%) Frame = +1 Query: 142 GIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPHIIRLYEV 321 G G+FG K+ ++T A+K + R ++E V+REI R HP+IIR EV Sbjct: 1 GSGNFGVAKLVRDVRTKEHFAVKFIER----GHKIDEHVQREIMNHRSLKHPNIIRFKEV 56 Query: 322 IEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMVVHRDLKP 501 + P + +VMEY GELF I GR E E R FFQQ+ISGV YCH V HRDLK Sbjct: 57 VLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFFQQLISGVSYCHSMQVCHRDLKL 116 Query: 502 ENLLLDNNC--DVKIADFGLS 558 EN LLD + +KI DFG S Sbjct: 117 ENTLLDGSVAPRLKICDFGYS 137
>DAPK2_HUMAN (Q9UIK4) Death-associated protein kinase 2 (EC 2.7.11.1) (DAP| kinase 2) (DAP-kinase-related protein 1) (DRP-1) Length = 370 Score = 118 bits (296), Expect = 1e-26 Identities = 63/159 (39%), Positives = 95/159 (59%), Gaps = 7/159 (4%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDM---EEKVKREIKILRLFM 291 Y IG+ LG G F VK TG + A K + +R+ + E+++RE+ ILR + Sbjct: 23 YDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREVSILRQVL 82 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 H ++I L++V E D+ +++E V GELFD++ +K L E+EA F +QI+ GV Y H Sbjct: 83 HHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHT 142 Query: 472 NMVVHRDLKPEN-LLLDNNC---DVKIADFGLSNVMRDG 576 + H DLKPEN +LLD N +K+ DFGL++ + DG Sbjct: 143 KKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDG 181
>KAPB_YEAST (P06245) cAMP-dependent protein kinase type 2 (EC 2.7.11.11) (PKA| 2) Length = 380 Score = 117 bits (294), Expect = 2e-26 Identities = 53/149 (35%), Positives = 93/149 (62%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 L +++I +TLG GSFG+V + + G AIK+L ++++ M E E ++L+L Sbjct: 67 LHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVE 126 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 HP +IR++ + +I++VM+Y++ GELF + + R A+ + ++I ++Y H Sbjct: 127 HPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHA 186 Query: 472 NMVVHRDLKPENLLLDNNCDVKIADFGLS 558 + +++RDLKPEN+LLD N +KI DFG + Sbjct: 187 HNIIYRDLKPENILLDRNGHIKITDFGFA 215
>DAPK3_RAT (O88764) Death-associated protein kinase 3 (EC 2.7.11.1) (DAP| kinase 3) (DAP-like kinase) (Dlk) (ZIP-kinase) Length = 448 Score = 117 bits (294), Expect = 2e-26 Identities = 61/160 (38%), Positives = 97/160 (60%), Gaps = 7/160 (4%) Frame = +1 Query: 118 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDM---EEKVKREIKILRLF 288 +Y +G+ LG G F V+ + TG + A K + +R++ + E+++RE+ ILR Sbjct: 12 HYEMGEELGSGQFAIVRKCQQKGTGMEYAAKFIKKRRLPSSRRGVSREEIEREVSILREI 71 Query: 289 MHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCH 468 HP+II L++V E D+ +++E V GELFD++ EK L E EA +F +QI+ GV Y H Sbjct: 72 RHPNIITLHDVFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLH 131 Query: 469 RNMVVHRDLKPEN-LLLDNNC---DVKIADFGLSNVMRDG 576 + H DLKPEN +LLD + +K+ DFG+++ + G Sbjct: 132 SKRIAHFDLKPENIMLLDKHAASPRIKLIDFGIAHRIEAG 171
>DAPK3_MOUSE (O54784) Death-associated protein kinase 3 (EC 2.7.11.1) (DAP| kinase 3) (DAP-like kinase) (Dlk) (ZIP-kinase) Length = 448 Score = 117 bits (294), Expect = 2e-26 Identities = 61/160 (38%), Positives = 97/160 (60%), Gaps = 7/160 (4%) Frame = +1 Query: 118 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDM---EEKVKREIKILRLF 288 +Y +G+ LG G F V+ + TG + A K + +R++ + E+++RE+ ILR Sbjct: 12 HYEMGEELGSGQFAIVRKCQQKGTGMEYAAKFIKKRRLPSSRRGVSREEIEREVSILREI 71 Query: 289 MHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCH 468 HP+II L++V E D+ +++E V GELFD++ EK L E EA +F +QI+ GV Y H Sbjct: 72 RHPNIITLHDVFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLH 131 Query: 469 RNMVVHRDLKPEN-LLLDNNC---DVKIADFGLSNVMRDG 576 + H DLKPEN +LLD + +K+ DFG+++ + G Sbjct: 132 SKRIAHFDLKPENIMLLDKHAASPRIKLIDFGIAHRIEAG 171
>TSSK1_HUMAN (Q9BXA7) Testis-specific serine/threonine-protein kinase 1 (EC| 2.7.11.1) (TSSK-1) (Testis-specific kinase 1) (TSK-1) (Serine/threonine-protein kinase 22A) Length = 367 Score = 117 bits (294), Expect = 2e-26 Identities = 63/149 (42%), Positives = 92/149 (61%), Gaps = 1/149 (0%) Frame = +1 Query: 115 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 294 + Y +G LG GS+ KVK A + VAIKI++R+K +E+ + REI+IL + H Sbjct: 10 RGYLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPREIEILAMLNH 69 Query: 295 PHIIRLYEVIEAP-ADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 II+ YE+ E +Y+VME G+L + I +G L E EAR+ F Q+ ++YCH Sbjct: 70 CSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSLAIKYCHD 129 Query: 472 NMVVHRDLKPENLLLDNNCDVKIADFGLS 558 VVHRDLK +NLLLD + ++K++DF S Sbjct: 130 LDVVHRDLKCDNLLLDKDFNIKLSDFSFS 158
>CHK1_DROME (O61661) Serine/threonine-protein kinase grp (EC 2.7.11.1) (Protein| grapes) (Chk1 homolog) Length = 512 Score = 117 bits (294), Expect = 2e-26 Identities = 57/153 (37%), Positives = 99/153 (64%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 ++ + + +TLG G++G+VK+ + +TG VA+K+++ +K + D V++E+ I ++ Sbjct: 19 VEGWTLAQTLGEGAYGEVKLLINRQTGEAVAMKMVDLKK--HPDAANSVRKEVCIQKMLQ 76 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 HI+R + + Y+ +EY GELFD I + + EA+R+F Q++SG+ Y H+ Sbjct: 77 DKHILRFFGKRSQGSVEYIFLEYAAGGELFDRIEPDVGMPQHEAQRYFTQLLSGLNYLHQ 136 Query: 472 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMR 570 + HRDLKPENLLLD + +VKI+DFG++ + R Sbjct: 137 RGIAHRDLKPENLLLDEHDNVKISDFGMATMFR 169
>KCC1_SCHPO (Q9P7I2) Calcium/calmodulin-dependent protein kinase type I (EC| 2.7.11.17) (CaMK-I) Length = 335 Score = 117 bits (294), Expect = 2e-26 Identities = 65/159 (40%), Positives = 94/159 (59%), Gaps = 5/159 (3%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRL--FMH 294 YR+G+ LG G++ V+ A HI+T A KI+N++ ++ ++ VK EI IL+ + H Sbjct: 31 YRVGRVLGGGTYATVREAVHIETNKMYAAKIMNKKMMEKK--QDFVKNEIAILKRVSYEH 88 Query: 295 PHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRN 474 P+I+ L + E ++Y++ E GELFD I KG E +A + S V+Y H N Sbjct: 89 PNILHLVDFFETVNNLYLITELATGGELFDRICAKGSFYEADAAALMRTTTSAVKYLHDN 148 Query: 475 MVVHRDLKPENLLL---DNNCDVKIADFGLSNVMRDGHF 582 +VHRDLKPENLL D N D+ IADFGLS+ D + Sbjct: 149 GIVHRDLKPENLLYRSKDPNSDLLIADFGLSHFYEDSQY 187
>PLK4_MOUSE (Q64702) Serine/threonine-protein kinase PLK4 (EC 2.7.11.21)| (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine-protein kinase 18) Length = 925 Score = 117 bits (293), Expect = 2e-26 Identities = 60/160 (37%), Positives = 98/160 (61%), Gaps = 1/160 (0%) Frame = +1 Query: 103 GNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILR 282 G ++++++G LG GSF V AE I TG +VAIK+++++ + M ++V+ E+KI Sbjct: 6 GERIEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHC 65 Query: 283 LFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGR-LQEQEARRFFQQIISGVQ 459 HP ++ LY E +Y+V+E +GE+ Y+ + + E+EAR F QII+G+ Sbjct: 66 QLKHPSVLELYNYFEDNNYVYLVLEMCHNGEMNRYLKNRMKPFSEREARHFMHQIITGML 125 Query: 460 YCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGH 579 Y H + ++HRDL N+LL N ++KIADFGL+ + H Sbjct: 126 YLHSHGILHRDLTLSNILLTRNMNIKIADFGLATQLNMPH 165
>KCC2D_RAT (P15791) Calcium/calmodulin-dependent protein kinase type II delta| chain (EC 2.7.11.17) (CaM-kinase II delta chain) (CaM kinase II delta subunit) (CaMK-II delta subunit) Length = 533 Score = 117 bits (293), Expect = 2e-26 Identities = 64/149 (42%), Positives = 91/149 (61%), Gaps = 3/149 (2%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 Y++ + LG G+F V+ I TG + A KI+N +K+ D +K++RE +I RL HP+ Sbjct: 14 YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARD-HQKLEREARICRLLKHPN 72 Query: 301 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 480 I+RL++ I Y+V + V GELF+ IV + E +A QQI+ V +CH N + Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGI 132 Query: 481 VHRDLKPENLLL---DNNCDVKIADFGLS 558 VHRDLKPENLLL VK+ADFGL+ Sbjct: 133 VHRDLKPENLLLASKSKGAAVKLADFGLA 161
>TSSK2_MOUSE (O54863) Testis-specific serine/threonine-protein kinase 2 (EC| 2.7.11.1) (TSSK-2) (Testis-specific kinase 2) (TSK-2) (Serine/threonine-protein kinase 22B) Length = 357 Score = 117 bits (293), Expect = 2e-26 Identities = 67/156 (42%), Positives = 94/156 (60%), Gaps = 2/156 (1%) Frame = +1 Query: 115 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 294 K Y +G LG GS+ KVK A + VA+KI++R+K +E + RE+ IL H Sbjct: 10 KGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNH 69 Query: 295 PHIIRLYEVIE-APADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 II+ YE+ E + IY+VME G+L +I +G L E + F+Q+ S V+YCH Sbjct: 70 RSIIKTYEIFETSDGRIYIVMELGVQGDLLTFIKCRGALHEDVGGKMFRQVSSAVKYCHD 129 Query: 472 NMVVHRDLKPENLLLDNNCDVKIADFGLS-NVMRDG 576 VVHRDLK ENLLLD + ++K++DFG S +RDG Sbjct: 130 LDVVHRDLKCENLLLDKDFNIKLSDFGFSKGCLRDG 165
>SAPK8_ORYSA (Q7Y0B9) Serine/threonine-protein kinase SAPK8 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 8) Length = 371 Score = 117 bits (293), Expect = 2e-26 Identities = 66/148 (44%), Positives = 88/148 (59%), Gaps = 2/148 (1%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 Y + + +G G+FG ++ +T VA+K + R + +++ V+REI R HP+ Sbjct: 33 YELVRDIGSGNFGVARLMRDRRTMELVAVKYIERGE----KIDDNVQREIINHRSLKHPN 88 Query: 301 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 480 IIR EVI P + +VMEY GELF+ I + R E EAR FFQQ+ISGV YCH V Sbjct: 89 IIRFKEVILTPTHLAIVMEYASGGELFERICKNVRFSEDEARYFFQQLISGVSYCHSMQV 148 Query: 481 VHRDLKPENLLLDNN--CDVKIADFGLS 558 HRDLK EN LLD + +KI DFG S Sbjct: 149 CHRDLKLENTLLDGSPAPRLKICDFGYS 176
>KCC2A_DROME (Q00168) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) Length = 530 Score = 117 bits (293), Expect = 2e-26 Identities = 67/157 (42%), Positives = 95/157 (60%), Gaps = 3/157 (1%) Frame = +1 Query: 118 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 297 NY I + LG G+F VK TG + A KI+N +K+ D + K++RE +I R HP Sbjct: 13 NYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQ-KLEREARICRKLHHP 71 Query: 298 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 477 +I+RL++ I+ Y+V + V GELF+ IV + E +A QQI+ V +CH+N Sbjct: 72 NIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNG 131 Query: 478 VVHRDLKPENLLLDNNCD---VKIADFGLSNVMRDGH 579 VVHRDLKPENLLL + VK+ADFGL+ ++ H Sbjct: 132 VVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDH 168
>AURKB_MOUSE (O70126) Serine/threonine-protein kinase 12 (EC 2.7.11.1)| (Aurora-related kinase 2) (Serine/threonine-protein kinase 5) (STK-1) (Aurora-B) Length = 345 Score = 116 bits (291), Expect = 4e-26 Identities = 57/149 (38%), Positives = 89/149 (59%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 + N+ IG+ LG G FG V +A K+ VA+KIL + +I+ +E +++REI+I Sbjct: 79 IDNFEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQIEKEGVEHQLRREIEIQAHLK 138 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 HP+I++LY IY+++EY GEL+ + + EQ +++ + YCH+ Sbjct: 139 HPNILQLYNYFYDQQRIYLILEYAPRGELYKELQKSRTFDEQRTATIMEELSDALTYCHK 198 Query: 472 NMVVHRDLKPENLLLDNNCDVKIADFGLS 558 V+HRD+KPENLLL ++KIADFG S Sbjct: 199 KKVIHRDIKPENLLLGLQGELKIADFGWS 227
>AURKC_HUMAN (Q9UQB9) Serine/threonine-protein kinase 13 (EC 2.7.11.1)| (Aurora/Ipl1/Eg2 protein 2) (Aurora/Ipl1-related kinase 3) (Aurora-C) Length = 309 Score = 116 bits (291), Expect = 4e-26 Identities = 56/147 (38%), Positives = 89/147 (60%) Frame = +1 Query: 118 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 297 ++ IG+ LG G FG V +A ++ VA+K+L + +I+ +E +++REI+I HP Sbjct: 42 DFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHP 101 Query: 298 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 477 +I+RLY +Y+++EY GEL+ + + +L EQ +++ + YCH Sbjct: 102 NILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKK 161 Query: 478 VVHRDLKPENLLLDNNCDVKIADFGLS 558 V+HRD+KPENLLL +VKIADFG S Sbjct: 162 VIHRDIKPENLLLGFRGEVKIADFGWS 188
>KCC2D_HUMAN (Q13557) Calcium/calmodulin-dependent protein kinase type II delta| chain (EC 2.7.11.17) (CaM-kinase II delta chain) (CaM kinase II delta subunit) (CaMK-II delta subunit) Length = 499 Score = 116 bits (290), Expect = 5e-26 Identities = 64/149 (42%), Positives = 90/149 (60%), Gaps = 3/149 (2%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 Y++ + LG G+F V+ I TG A KI+N +K+ D +K++RE +I RL HP+ Sbjct: 14 YQLFEELGKGAFSVVRRCMKIPTGQGYAAKIINTKKLSARD-HQKLEREARICRLLKHPN 72 Query: 301 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 480 I+RL++ I Y+V + V GELF+ IV + E +A QQI+ V +CH N + Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGI 132 Query: 481 VHRDLKPENLLL---DNNCDVKIADFGLS 558 VHRDLKPENLLL VK+ADFGL+ Sbjct: 133 VHRDLKPENLLLASKSKGAAVKLADFGLA 161
>KCC2B_RAT (P08413) Calcium/calmodulin-dependent protein kinase type II beta| chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II beta subunit) (CaMK-II beta subunit) Length = 542 Score = 116 bits (290), Expect = 5e-26 Identities = 63/149 (42%), Positives = 93/149 (62%), Gaps = 3/149 (2%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 Y++ + +G G+F V+ + TGH+ A KI+N +K+ D +K++RE +I RL H + Sbjct: 14 YQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARD-HQKLEREARICRLLKHSN 72 Query: 301 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 480 I+RL++ I Y+V + V GELF+ IV + E +A QQI+ V +CH+ V Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 132 Query: 481 VHRDLKPENLLLDNNCD---VKIADFGLS 558 VHRDLKPENLLL + C VK+ADFGL+ Sbjct: 133 VHRDLKPENLLLASKCKGAAVKLADFGLA 161
>KCC2B_MOUSE (P28652) Calcium/calmodulin-dependent protein kinase type II beta| chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II beta subunit) (CaMK-II beta subunit) Length = 542 Score = 116 bits (290), Expect = 5e-26 Identities = 63/149 (42%), Positives = 93/149 (62%), Gaps = 3/149 (2%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 Y++ + +G G+F V+ + TGH+ A KI+N +K+ D +K++RE +I RL H + Sbjct: 14 YQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARD-HQKLEREARICRLLKHSN 72 Query: 301 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 480 I+RL++ I Y+V + V GELF+ IV + E +A QQI+ V +CH+ V Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 132 Query: 481 VHRDLKPENLLLDNNCD---VKIADFGLS 558 VHRDLKPENLLL + C VK+ADFGL+ Sbjct: 133 VHRDLKPENLLLASKCKGAAVKLADFGLA 161
>ASK1_ARATH (P43291) Serine/threonine-protein kinase ASK1 (EC 2.7.11.1)| Length = 363 Score = 116 bits (290), Expect = 5e-26 Identities = 65/151 (43%), Positives = 86/151 (56%), Gaps = 2/151 (1%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 + Y + K +G G+FG ++ + + VA+K + R ++E V REI R Sbjct: 1 MDKYELVKDIGAGNFGVARLMKVKNSKELVAMKYIER----GPKIDENVAREIINHRSLR 56 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 HP+IIR EV+ P + + MEY GELF+ I GR E EAR FFQQ+ISGV YCH Sbjct: 57 HPNIIRFKEVVLTPTHLAIAMEYAAGGELFERICSAGRFSEDEARYFFQQLISGVSYCHA 116 Query: 472 NMVVHRDLKPENLLLDNN--CDVKIADFGLS 558 + HRDLK EN LLD + +KI DFG S Sbjct: 117 MQICHRDLKLENTLLDGSPAPRLKICDFGYS 147
>KCC2B_HUMAN (Q13554) Calcium/calmodulin-dependent protein kinase type II beta| chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II beta subunit) (CaMK-II beta subunit) Length = 664 Score = 116 bits (290), Expect = 5e-26 Identities = 63/149 (42%), Positives = 93/149 (62%), Gaps = 3/149 (2%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 Y++ + +G G+F V+ + TGH+ A KI+N +K+ D +K++RE +I RL H + Sbjct: 14 YQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARD-HQKLEREARICRLLKHSN 72 Query: 301 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 480 I+RL++ I Y+V + V GELF+ IV + E +A QQI+ V +CH+ V Sbjct: 73 IVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGV 132 Query: 481 VHRDLKPENLLLDNNCD---VKIADFGLS 558 VHRDLKPENLLL + C VK+ADFGL+ Sbjct: 133 VHRDLKPENLLLASKCKGAAVKLADFGLA 161
>KAPCG_HUMAN (P22612) cAMP-dependent protein kinase, gamma-catalytic subunit (EC| 2.7.11.11) (PKA C-gamma) Length = 350 Score = 115 bits (289), Expect = 7e-26 Identities = 60/158 (37%), Positives = 93/158 (58%), Gaps = 6/158 (3%) Frame = +1 Query: 103 GNPLKN------YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKR 264 GNP +N + +TLG+GSFG+V + H +TG A+KILN++K+ M E + Sbjct: 31 GNPAQNTASSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILN 90 Query: 265 EIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQI 444 E +IL+ P +++L + + +Y+VMEYV GE+F + GR E A + Q+ Sbjct: 91 EKRILQAIDFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQV 150 Query: 445 ISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLS 558 + VQY H ++HRDLKPENLL+D +++ DFG + Sbjct: 151 VLAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFA 188
>DCAK1_HUMAN (O15075) Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 1) Length = 740 Score = 115 bits (288), Expect = 9e-26 Identities = 56/155 (36%), Positives = 93/155 (60%), Gaps = 4/155 (2%) Frame = +1 Query: 115 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 294 + Y++G+T+G G+F VK T + A+KI+ + K + E ++ E+ ILR H Sbjct: 388 ERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGK--EHMIQNEVSILRRVKH 445 Query: 295 PHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRN 474 P+I+ L E ++ P ++Y+VME VK G+LFD I + E++A + S ++Y H Sbjct: 446 PNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSL 505 Query: 475 MVVHRDLKPENLLL----DNNCDVKIADFGLSNVM 567 +VHRD+KPENLL+ D + +K+ DFGL+ ++ Sbjct: 506 NIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIV 540
>KK31_SCHPO (Q9HFF4) Probable serine/threonine-protein kinase C110.01 (EC| 2.7.11.1) Length = 1023 Score = 115 bits (288), Expect = 9e-26 Identities = 66/165 (40%), Positives = 96/165 (58%), Gaps = 10/165 (6%) Frame = +1 Query: 118 NYRIGKTLGIGSFGKVKIAEHIKTGH--------KVAIKILNRRKIKNMDMEEKVKREIK 273 +Y +G+T+G G FGKVK+ + + +V IKI+ K ++ RE+ Sbjct: 491 SYILGRTIGTGEFGKVKLGWPLPKANSTIHRSTPQVVIKIV--LSTKQNCQTSRLMREVA 548 Query: 274 ILRLF--MHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQII 447 IL+ HPHI++ + ++ +V++YV GELFDYI+ + RL++ A R F Q+I Sbjct: 549 ILKGLGNNHPHIVKYLDFVKTKHHFGIVLDYVNGGELFDYILARRRLEDSVACRLFAQLI 608 Query: 448 SGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHF 582 SGV Y H VVHRDLK EN+LLD N ++ IADFG + GHF Sbjct: 609 SGVAYLHSRGVVHRDLKLENILLDTNRNIVIADFGFATTF--GHF 651
>ARK1_SCHPO (O59790) Serine/threonine-protein kinase ark1 (EC 2.7.11.1)| (Aurora-related kinase 1) Length = 355 Score = 115 bits (288), Expect = 9e-26 Identities = 55/146 (37%), Positives = 93/146 (63%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 + IGK LG G FG+V +A+ KTG VA+K L++ ++ +E++V+REI+I H + Sbjct: 89 FEIGKPLGKGKFGRVYLAKEKKTGFIVALKTLHKSELVQSKIEKQVRREIEIQSNLRHKN 148 Query: 301 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 480 I+RLY IY+++E+ GEL+ ++ R E+ A ++ Q+ + + Y H+ V Sbjct: 149 ILRLYGHFHDEKRIYLILEFAGRGELYQHLRRAKRFSEEVASKYIFQMANALSYLHKKHV 208 Query: 481 VHRDLKPENLLLDNNCDVKIADFGLS 558 +HRD+KPEN+LL + ++K++DFG S Sbjct: 209 IHRDIKPENILLGIDGEIKLSDFGWS 234
>SAPK5_ORYSA (Q7XKA8) Serine/threonine-protein kinase SAPK5 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 5) Length = 370 Score = 115 bits (288), Expect = 9e-26 Identities = 65/151 (43%), Positives = 87/151 (57%), Gaps = 2/151 (1%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 ++ Y + +G G+FG K+ + +T VA+K + R ++E V REI R Sbjct: 1 MEKYEPVREIGAGNFGVAKLMRNKETRELVAMKFIERGN----RIDENVFREIVNHRSLR 56 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 HP+IIR EV+ + +VMEY GELF+ I E GR E EAR FFQQ++ GV YCH Sbjct: 57 HPNIIRFKEVVVTGRHLAIVMEYAAGGELFERICEAGRFHEDEARYFFQQLVCGVSYCHA 116 Query: 472 NMVVHRDLKPENLLLDNN--CDVKIADFGLS 558 + HRDLK EN LLD + +KI DFG S Sbjct: 117 MQICHRDLKLENTLLDGSPAPRLKICDFGYS 147
>AURKC_MOUSE (O88445) Serine/threonine-protein kinase 13 (EC 2.7.11.1)| (Aurora/Ipl1/Eg2 protein 1) (Aurora-C) Length = 282 Score = 115 bits (287), Expect = 1e-25 Identities = 55/149 (36%), Positives = 89/149 (59%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 + ++ IG+ LG G FG+V +A + VA+K+L + +I+ +E +++RE++I Sbjct: 13 INDFEIGRPLGRGKFGRVYLARLKENHFIVALKVLFKSEIEKEGLEHQLRREVEIQAHLQ 72 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 H +I+RLY IY+++EY GEL+ + +L +Q Q++ + YCH Sbjct: 73 HRNILRLYNYFYDDTRIYLILEYAPGGELYKELQRHQKLDQQRTATIIQELSDALTYCHE 132 Query: 472 NMVVHRDLKPENLLLDNNCDVKIADFGLS 558 V+HRD+KPENLLL N +VKI+DFG S Sbjct: 133 KKVIHRDIKPENLLLGLNGEVKISDFGWS 161
>KCC1A_RAT (Q63450) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 374 Score = 115 bits (287), Expect = 1e-25 Identities = 67/174 (38%), Positives = 99/174 (56%), Gaps = 3/174 (1%) Frame = +1 Query: 73 RWKMEAGGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEE 252 RWK +D Y LG G+F +V +AE +T VAIK + ++ ++ E Sbjct: 9 RWKQAEDIRD-----IYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKKALEGK--EG 61 Query: 253 KVKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRF 432 ++ EI +L HP+I+ L ++ E+ +Y++M+ V GELFD IVEKG E++A R Sbjct: 62 SMENEIAVLHKIKHPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRL 121 Query: 433 FQQIISGVQYCHRNMVVHRDLKPENLL---LDNNCDVKIADFGLSNVMRDGHFL 585 Q++ V+Y H +VHRDLKPENLL LD + + I+DFGLS + G L Sbjct: 122 IFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPGSVL 175
>KCC1A_MOUSE (Q91YS8) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 374 Score = 115 bits (287), Expect = 1e-25 Identities = 67/174 (38%), Positives = 99/174 (56%), Gaps = 3/174 (1%) Frame = +1 Query: 73 RWKMEAGGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEE 252 RWK +D Y LG G+F +V +AE +T VAIK + ++ ++ E Sbjct: 9 RWKQAEDIRD-----IYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKKALEGK--EG 61 Query: 253 KVKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRF 432 ++ EI +L HP+I+ L ++ E+ +Y++M+ V GELFD IVEKG E++A R Sbjct: 62 SMENEIAVLHKIKHPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRL 121 Query: 433 FQQIISGVQYCHRNMVVHRDLKPENLL---LDNNCDVKIADFGLSNVMRDGHFL 585 Q++ V+Y H +VHRDLKPENLL LD + + I+DFGLS + G L Sbjct: 122 IFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPGSVL 175
>DCAK1_RAT (O08875) Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 1) (Calcium/calmodulin-dependent protein kinase type I-like CPG16) Length = 433 Score = 115 bits (287), Expect = 1e-25 Identities = 56/155 (36%), Positives = 93/155 (60%), Gaps = 4/155 (2%) Frame = +1 Query: 115 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 294 + Y++G+T+G G+F VK T + A+KI+ + K + E ++ E+ ILR H Sbjct: 81 ERYKVGRTIGDGNFAVVKECIERSTAREYALKIIKKSKCRGK--EHMIQNEVSILRRVKH 138 Query: 295 PHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRN 474 P+I+ L E ++ P ++Y+VME VK G+LFD I + E++A + S ++Y H Sbjct: 139 PNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTSKYTERDASGMLYNLASAIKYLHSL 198 Query: 475 MVVHRDLKPENLLL----DNNCDVKIADFGLSNVM 567 +VHRD+KPENLL+ D + +K+ DFGL+ ++ Sbjct: 199 NIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIV 233
>DCAK1_MOUSE (Q9JLM8) Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 1) Length = 756 Score = 115 bits (287), Expect = 1e-25 Identities = 56/155 (36%), Positives = 93/155 (60%), Gaps = 4/155 (2%) Frame = +1 Query: 115 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 294 + Y++G+T+G G+F VK T + A+KI+ + K + E ++ E+ ILR H Sbjct: 404 ERYKVGRTIGDGNFAVVKECIERSTAREYALKIIKKSKCRGK--EHMIQNEVSILRRVKH 461 Query: 295 PHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRN 474 P+I+ L E ++ P ++Y+VME VK G+LFD I + E++A + S ++Y H Sbjct: 462 PNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTSKYTERDASGMLYNLASAIKYLHSL 521 Query: 475 MVVHRDLKPENLLL----DNNCDVKIADFGLSNVM 567 +VHRD+KPENLL+ D + +K+ DFGL+ ++ Sbjct: 522 NIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIV 556
>TSSK4_HUMAN (Q6SA08) Testis-specific serine/threonine-protein kinase 4 (EC| 2.7.11.1) (TSSK-4) (Testis-specific kinase 4) (TSK-4) (Serine/threonine-protein kinase 22E) Length = 328 Score = 115 bits (287), Expect = 1e-25 Identities = 53/149 (35%), Positives = 94/149 (63%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 Y +GK +G GS+G V A + K VA+KI++++K + + + + REI+++++ H + Sbjct: 25 YEVGKAIGHGSYGSVYEAFYTKQKVMVAVKIISKKKASDDYLNKFLPREIQVMKVLRHKY 84 Query: 301 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 480 +I Y IE+ + +Y+++E + G++ ++I G E A ++F Q+ G+ Y H + Sbjct: 85 LINFYRAIESTSRVYIILELAQGGDVLEWIQRYGACSEPLAGKWFSQLTLGIAYLHSKSI 144 Query: 481 VHRDLKPENLLLDNNCDVKIADFGLSNVM 567 VHRDLK ENLLLD +VKI+DFG + ++ Sbjct: 145 VHRDLKLENLLLDKWENVKISDFGFAKMV 173
>ICL1_KLULA (Q6CWQ4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 361 Score = 114 bits (286), Expect = 2e-25 Identities = 56/155 (36%), Positives = 92/155 (59%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 L+++ IGK LG G FGKV +H +TG A+K + +++I ++++ +RE++I F Sbjct: 97 LQDFEIGKILGKGKFGKVYCVKHRETGLICALKAMEKKEIVQYTIQKQFRREVEIQGSFK 156 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 H ++ +LY +Y++MEYV GEL+ ++ G L E A F Q+ + + Y H Sbjct: 157 HKNLTQLYGFFYDEKRVYLLMEYVYYGELYKFLKNNGPLNETLASYFVYQMANALDYMHS 216 Query: 472 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDG 576 ++HRD+KPEN+L+ N +K+ DFG S DG Sbjct: 217 KNILHRDIKPENILIGFNNTIKLTDFGWSVYNEDG 251
>STK6_MOUSE (P97477) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Aurora-family kinase 1) (Aurora/IPL1-related kinase 1) (Ipl1- and aurora-related kinase 1) (Aurora-A) (Serine/threonine-protein kinase Ayk1) Length = 395 Score = 114 bits (286), Expect = 2e-25 Identities = 51/149 (34%), Positives = 93/149 (62%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 L+++ IG+ LG G FG V +A ++ +A+K+L + +++ ++E +++RE++I Sbjct: 121 LEDFDIGRPLGKGKFGNVYLARERQSKFILALKVLFKTQLEKANVEHQLRREVEIQSHLR 180 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 HP+I+RLY +Y+++EY G ++ + + + EQ + ++ + + YCH Sbjct: 181 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHS 240 Query: 472 NMVVHRDLKPENLLLDNNCDVKIADFGLS 558 V+HRD+KPENLLL +N ++KIADFG S Sbjct: 241 KRVIHRDIKPENLLLGSNGELKIADFGWS 269
>CHK1_MOUSE (O35280) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 114 bits (286), Expect = 2e-25 Identities = 59/153 (38%), Positives = 99/153 (64%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 ++++ + +TLG G++G+V++A + T VA+KI++ ++ +D E +K+EI I ++ Sbjct: 6 VEDWDLVQTLGEGAYGEVQLAVNRITEEAVAVKIVDMKRA--IDCPENIKKEICINKMLS 63 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 H ++++ Y Y+ +EY GELFD I + EQ+A+RFF Q+++GV Y H Sbjct: 64 HENVVKFYGHRREGHIQYLFLEYCSGGELFDRIEPDIGMPEQDAQRFFHQLMAGVVYLHG 123 Query: 472 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMR 570 + HRD+KPENLLLD ++KI+DFGL+ V R Sbjct: 124 IGITHRDIKPENLLLDERDNLKISDFGLATVFR 156
>TSSK4_MOUSE (Q9D411) Testis-specific serine/threonine-protein kinase 4 (EC| 2.7.11.1) (TSSK-4) (Testis-specific kinase 4) (TSK-4) Length = 328 Score = 114 bits (286), Expect = 2e-25 Identities = 53/149 (35%), Positives = 93/149 (62%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 Y +GK +G GS+G V A + K VA+KI++++K + + + REI+++++ H + Sbjct: 25 YEVGKIIGHGSYGTVYEAYYTKQKVMVAVKIISKKKASEDYLNKFLPREIQVMKVLRHKY 84 Query: 301 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 480 +I Y+ IE + +Y+++E + G++ ++I G E A ++F Q+ G+ Y H + Sbjct: 85 LINFYQAIETTSRVYIILELAQGGDVLEWIQRYGACAETLAGKWFSQMALGIAYLHSKGI 144 Query: 481 VHRDLKPENLLLDNNCDVKIADFGLSNVM 567 VHRDLK ENLLLD +VKI+DFG + ++ Sbjct: 145 VHRDLKLENLLLDKRENVKISDFGFAKMV 173
>CHK1_RAT (Q91ZN7) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 114 bits (285), Expect = 2e-25 Identities = 59/153 (38%), Positives = 99/153 (64%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 ++++ + +TLG G++G+V++A + T VA+KI++ ++ +D E +K+EI I ++ Sbjct: 6 VEDWDLVQTLGEGAYGEVQLAVNRITEEAVAVKIVDMKRA--IDCPENIKKEICINKMLN 63 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 H ++++ Y Y+ +EY GELFD I + EQ+A+RFF Q+++GV Y H Sbjct: 64 HENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEQDAQRFFHQLMAGVVYLHG 123 Query: 472 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMR 570 + HRD+KPENLLLD ++KI+DFGL+ V R Sbjct: 124 IGITHRDIKPENLLLDERDNLKISDFGLATVFR 156
>KCC1A_HUMAN (Q14012) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 370 Score = 114 bits (285), Expect = 2e-25 Identities = 67/174 (38%), Positives = 98/174 (56%), Gaps = 3/174 (1%) Frame = +1 Query: 73 RWKMEAGGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEE 252 RWK +D Y LG G+F +V +AE +T VAIK + + ++ E Sbjct: 9 RWKQAEDIRD-----IYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGK--EG 61 Query: 253 KVKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRF 432 ++ EI +L HP+I+ L ++ E+ +Y++M+ V GELFD IVEKG E++A R Sbjct: 62 SMENEIAVLHKIKHPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRL 121 Query: 433 FQQIISGVQYCHRNMVVHRDLKPENLL---LDNNCDVKIADFGLSNVMRDGHFL 585 Q++ V+Y H +VHRDLKPENLL LD + + I+DFGLS + G L Sbjct: 122 IFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPGSVL 175
>KCC1B_RAT (O70150) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase homolog) Length = 343 Score = 114 bits (284), Expect = 3e-25 Identities = 59/151 (39%), Positives = 92/151 (60%), Gaps = 3/151 (1%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 Y I + LG G+F +V +A+ + H VA+K + ++ ++ E V+ EI +LR HP+ Sbjct: 15 YEIREKLGSGAFSEVMLAQERGSAHLVALKCIPKKALRGK--EALVENEIAVLRRISHPN 72 Query: 301 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 480 I+ L +V E+P+ +Y+ ME V GELFD I+E+G E++A Q++ V Y H + Sbjct: 73 IVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGI 132 Query: 481 VHRDLKPENLLLD---NNCDVKIADFGLSNV 564 VHRDLKPENLL + + ++DFGLS + Sbjct: 133 VHRDLKPENLLYATPFEDSKIMVSDFGLSKI 163
>KCC1B_MOUSE (Q9QYK9) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase homolog) Length = 343 Score = 114 bits (284), Expect = 3e-25 Identities = 59/151 (39%), Positives = 92/151 (60%), Gaps = 3/151 (1%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 Y I + LG G+F +V +A+ + H VA+K + ++ ++ E V+ EI +LR HP+ Sbjct: 15 YEIREKLGSGAFSEVMLAQERGSAHLVALKCIPKKALRGK--EALVENEIAVLRRISHPN 72 Query: 301 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 480 I+ L +V E+P+ +Y+ ME V GELFD I+E+G E++A Q++ V Y H + Sbjct: 73 IVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGI 132 Query: 481 VHRDLKPENLLLD---NNCDVKIADFGLSNV 564 VHRDLKPENLL + + ++DFGLS + Sbjct: 133 VHRDLKPENLLYATPFEDSKIMVSDFGLSKI 163
>AURKB_HUMAN (Q96GD4) Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-| and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (Aurora-related kinase 2) (STK-1) (Aurora-B) Length = 344 Score = 114 bits (284), Expect = 3e-25 Identities = 56/149 (37%), Positives = 88/149 (59%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 + ++ IG+ LG G FG V +A K+ VA+K+L + +I+ +E +++REI+I Sbjct: 74 IDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLH 133 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 HP+I+RLY IY+++EY GEL+ + + EQ +++ + YCH Sbjct: 134 HPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHG 193 Query: 472 NMVVHRDLKPENLLLDNNCDVKIADFGLS 558 V+HRD+KPENLLL ++KIADFG S Sbjct: 194 KKVIHRDIKPENLLLGLKGELKIADFGWS 222
>SSP1_SCHPO (P50526) Serine/threonine-protein kinase ssp1 (EC 2.7.11.1)| Length = 652 Score = 114 bits (284), Expect = 3e-25 Identities = 62/164 (37%), Positives = 100/164 (60%), Gaps = 9/164 (5%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRR-------KIKNMDMEEKVKREI 270 + +Y I K LG G GKVK+ T +AIKI+ + + +EKV+REI Sbjct: 132 INHYEIIKELGRGMHGKVKLGRDTVTRELLAIKIIPKTERRPKLGRANASSQKEKVRREI 191 Query: 271 KILRLFMHPHIIRLYEVIEAPAD--IYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQI 444 IL+ +HP+++RL EVI+ P+ +Y+V+EY+ GE+ + L EAR++F+ + Sbjct: 192 AILKKCVHPNVVRLREVIDDPSSTKVYLVLEYMSGGEVPWTDCDSPVLSISEARQYFRDV 251 Query: 445 ISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDG 576 + G++Y H ++HRD+KP NLLL+++ VKI+DFG+S + G Sbjct: 252 VLGLEYLHYQGIIHRDIKPANLLLNSSNCVKISDFGVSYIANAG 295
>KAPCG_MACMU (O62846) cAMP-dependent protein kinase, gamma-catalytic subunit (EC| 2.7.11.11) (PKA C-gamma) (Fragment) Length = 208 Score = 114 bits (284), Expect = 3e-25 Identities = 57/158 (36%), Positives = 94/158 (59%), Gaps = 6/158 (3%) Frame = +1 Query: 103 GNPLKN------YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKR 264 GNP +N + KTLG GS+G+V + H +TG+ A+KIL+++K+ + E Sbjct: 30 GNPAQNTASSDQFERLKTLGTGSYGRVMLVRHRETGNHYAMKILDKQKVVRLKQVEHTLN 89 Query: 265 EIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQI 444 E +IL+ P +++L + +++Y+VMEYV GE+F ++ GR E +A + Q+ Sbjct: 90 EKRILQAINFPFLVKLQFSFKDNSNLYLVMEYVPGGEMFSHLRRVGRFSEPQACFYAAQV 149 Query: 445 ISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLS 558 + QY H ++HRDLKPENLL+D +++ DFG + Sbjct: 150 VLAFQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFA 187
>STK6_RAT (P59241) Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Aurora-A)| (ratAurA) Length = 397 Score = 113 bits (283), Expect = 4e-25 Identities = 54/160 (33%), Positives = 95/160 (59%) Frame = +1 Query: 79 KMEAGGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKV 258 K E K L+++ IG+ LG G FG V +A ++ +A+K+L + +++ +E ++ Sbjct: 112 KTEDSKKRQWTLEDFDIGRPLGKGKFGNVYLAREKQSKFILALKVLFKVQLEKAGVEHQL 171 Query: 259 KREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQ 438 +RE++I HP+I+RLY +Y+++EY G ++ + + + EQ + Sbjct: 172 RREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYIT 231 Query: 439 QIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLS 558 ++ + + YCH V+HRD+KPENLLL +N ++KIADFG S Sbjct: 232 ELANALSYCHSKRVIHRDIKPENLLLGSNGELKIADFGWS 271
>KCC1B_HUMAN (Q6P2M8) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase) Length = 343 Score = 113 bits (283), Expect = 4e-25 Identities = 59/151 (39%), Positives = 92/151 (60%), Gaps = 3/151 (1%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 Y I + LG G+F +V +A+ + H VA+K + ++ ++ E V+ EI +LR HP+ Sbjct: 15 YEIRERLGSGAFSEVVLAQERGSAHLVALKCIPKKALRGK--EALVENEIAVLRRISHPN 72 Query: 301 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 480 I+ L +V E+P+ +Y+ ME V GELFD I+E+G E++A Q++ V Y H + Sbjct: 73 IVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGI 132 Query: 481 VHRDLKPENLLLD---NNCDVKIADFGLSNV 564 VHRDLKPENLL + + ++DFGLS + Sbjct: 133 VHRDLKPENLLYATPFEDSKIMVSDFGLSKI 163
>TSSK3_MOUSE (Q9D2E1) Testis-specific serine/threonine-protein kinase 3 (EC| 2.7.11.1) (TSSK-3) (Testis-specific kinase 3) (TSK-3) (Serine/threonine-protein kinase 22C) Length = 268 Score = 113 bits (282), Expect = 5e-25 Identities = 60/150 (40%), Positives = 96/150 (64%), Gaps = 1/150 (0%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 Y++GKT+G G++ KVK A K KVAIKI+++ ++ + RE++I+R H + Sbjct: 10 YQLGKTIGEGTYSKVKEAFSKKHQRKVAIKIIDKMGGPEEFIQRFLPRELQIVRTLDHKN 69 Query: 301 IIRLYEVIE-APADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 477 II++YE++E A IY+VME + G++FD ++ G L E A+ F+Q++ ++YCH Sbjct: 70 IIQVYEMLESADGKIYLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGCG 129 Query: 478 VVHRDLKPENLLLDNNCDVKIADFGLSNVM 567 V HRDLK EN LL ++K+ DFG + V+ Sbjct: 130 VAHRDLKCENALL-QGFNLKLTDFGFAKVL 158
>KAPCA_BOVIN (P00517) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 113 bits (282), Expect = 5e-25 Identities = 54/142 (38%), Positives = 90/142 (63%) Frame = +1 Query: 133 KTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPHIIRL 312 KTLG GSFG+V + +H++TG+ A+KIL+++K+ + E E +IL+ P +++L Sbjct: 47 KTLGTGSFGRVMLVKHMETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKL 106 Query: 313 YEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMVVHRD 492 + +++Y+VMEYV GE+F ++ GR E AR + QI+ +Y H +++RD Sbjct: 107 EFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRD 166 Query: 493 LKPENLLLDNNCDVKIADFGLS 558 LKPENLL+D +++ DFG + Sbjct: 167 LKPENLLIDQQGYIQVTDFGFA 188
>KPK2_PLAFK (Q02595) Probable serine/threonine-protein kinase 2 (EC 2.7.11.1)| Length = 510 Score = 112 bits (281), Expect = 6e-25 Identities = 60/152 (39%), Positives = 94/152 (61%), Gaps = 3/152 (1%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 Y + K +G GSF I +I G++V +K +++ K+K E V EI++LR MH + Sbjct: 111 YVLNKKIGKGSFSTAYIGTNILYGNRVVVKEVDKSKVK----ESNVYTEIEVLRKVMHKY 166 Query: 301 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 480 II+L E +Y+V+EY+K GELF+Y+ G EQ A++ ++++ ++ H N V Sbjct: 167 IIKLISAYEQEGFVYLVLEYLKGGELFEYLNNNGPYTEQVAKKAMKRVLIALEALHSNGV 226 Query: 481 VHRDLKPENLLLDNNCD---VKIADFGLSNVM 567 VHRDLK ENL+L+N D +KI DFGL++ + Sbjct: 227 VHRDLKMENLMLENPNDPSSLKIIDFGLASFL 258
>KCC2A_RAT (P11275) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 112 bits (281), Expect = 6e-25 Identities = 61/151 (40%), Positives = 92/151 (60%), Gaps = 3/151 (1%) Frame = +1 Query: 115 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 294 + Y++ + LG G+F V+ + G + A KI+N +K+ D +K++RE +I RL H Sbjct: 11 EEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARD-HQKLEREARICRLLKH 69 Query: 295 PHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRN 474 P+I+RL++ I Y++ + V GELF+ IV + E +A QQI+ V +CH+ Sbjct: 70 PNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQM 129 Query: 475 MVVHRDLKPENLLLDN---NCDVKIADFGLS 558 VVHRDLKPENLLL + VK+ADFGL+ Sbjct: 130 GVVHRDLKPENLLLASKLKGAAVKLADFGLA 160
>KCC2A_PONPY (Q5RCC4) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 112 bits (281), Expect = 6e-25 Identities = 61/151 (40%), Positives = 92/151 (60%), Gaps = 3/151 (1%) Frame = +1 Query: 115 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 294 + Y++ + LG G+F V+ + G + A KI+N +K+ D +K++RE +I RL H Sbjct: 11 EEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARD-HQKLEREARICRLLKH 69 Query: 295 PHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRN 474 P+I+RL++ I Y++ + V GELF+ IV + E +A QQI+ V +CH+ Sbjct: 70 PNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQM 129 Query: 475 MVVHRDLKPENLLLDN---NCDVKIADFGLS 558 VVHRDLKPENLLL + VK+ADFGL+ Sbjct: 130 GVVHRDLKPENLLLASKLKGAAVKLADFGLA 160
>KCC2A_HUMAN (Q9UQM7) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 112 bits (281), Expect = 6e-25 Identities = 61/151 (40%), Positives = 92/151 (60%), Gaps = 3/151 (1%) Frame = +1 Query: 115 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 294 + Y++ + LG G+F V+ + G + A KI+N +K+ D +K++RE +I RL H Sbjct: 11 EEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARD-HQKLEREARICRLLKH 69 Query: 295 PHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRN 474 P+I+RL++ I Y++ + V GELF+ IV + E +A QQI+ V +CH+ Sbjct: 70 PNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQM 129 Query: 475 MVVHRDLKPENLLLDN---NCDVKIADFGLS 558 VVHRDLKPENLLL + VK+ADFGL+ Sbjct: 130 GVVHRDLKPENLLLASKLKGAAVKLADFGLA 160
>KAPB2_BOVIN (P24256) cAMP-dependent protein kinase, beta-2-catalytic subunit| (EC 2.7.11.11) (PKA C-beta-2) Length = 397 Score = 112 bits (281), Expect = 6e-25 Identities = 58/162 (35%), Positives = 96/162 (59%) Frame = +1 Query: 73 RWKMEAGGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEE 252 +W+ A G L+++ KTLG GSFG+V + +H T A+KIL+++K+ + E Sbjct: 76 KWENPAPNNAG--LEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIE 133 Query: 253 KVKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRF 432 E +IL+ P ++RL + +++Y+VMEYV GE+F ++ GR E AR + Sbjct: 134 HTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFY 193 Query: 433 FQQIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLS 558 QI+ +Y H +++RDLKPENLL+D+ +++ DFG + Sbjct: 194 AAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFA 235
>KAPCA_HUMAN (P17612) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 112 bits (281), Expect = 6e-25 Identities = 57/160 (35%), Positives = 96/160 (60%) Frame = +1 Query: 79 KMEAGGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKV 258 K E+ ++ L + KTLG GSFG+V + +H +TG+ A+KIL+++K+ + E Sbjct: 29 KWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHT 88 Query: 259 KREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQ 438 E +IL+ P +++L + +++Y+VMEYV GE+F ++ GR E AR + Sbjct: 89 LNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAA 148 Query: 439 QIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLS 558 QI+ +Y H +++RDLKPENLL+D +++ DFG + Sbjct: 149 QIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFA 188
>KAPCA_CRIGR (P25321) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 112 bits (281), Expect = 6e-25 Identities = 57/160 (35%), Positives = 97/160 (60%) Frame = +1 Query: 79 KMEAGGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKV 258 K E+ ++ L ++ KTLG GSFG+V + +H +TG+ A+KIL+++K+ + E Sbjct: 29 KWESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHT 88 Query: 259 KREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQ 438 E +IL+ P +++L + +++Y+VMEYV GE+F ++ GR E AR + Sbjct: 89 LNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAA 148 Query: 439 QIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLS 558 QI+ +Y H +++RDLKPENLL+D +++ DFG + Sbjct: 149 QIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFA 188
>KAPB1_BOVIN (P05131) cAMP-dependent protein kinase, beta-1-catalytic subunit| (EC 2.7.11.11) (PKA C-beta-1) Length = 350 Score = 112 bits (281), Expect = 6e-25 Identities = 58/162 (35%), Positives = 96/162 (59%) Frame = +1 Query: 73 RWKMEAGGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEE 252 +W+ A G L+++ KTLG GSFG+V + +H T A+KIL+++K+ + E Sbjct: 29 KWENPAPNNAG--LEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIE 86 Query: 253 KVKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRF 432 E +IL+ P ++RL + +++Y+VMEYV GE+F ++ GR E AR + Sbjct: 87 HTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFY 146 Query: 433 FQQIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLS 558 QI+ +Y H +++RDLKPENLL+D+ +++ DFG + Sbjct: 147 AAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFA 188
>DCAK2_MOUSE (Q6PGN3) Serine/threonine-protein kinase DCAMKL2 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 2) Length = 756 Score = 112 bits (281), Expect = 6e-25 Identities = 61/156 (39%), Positives = 91/156 (58%), Gaps = 4/156 (2%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 L+ YRIGK +G G+F VK TG + A+KI++ K K E ++ E+ ILR Sbjct: 390 LEKYRIGKVIGDGNFAVVKECVDRYTGKEFALKIID--KAKCCGKEHLIENEVSILRRVK 447 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 HP+II L E +E D+++VME VK G+LFD I + E++ + + ++Y H Sbjct: 448 HPNIIMLVEEMETATDLFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHS 507 Query: 472 NMVVHRDLKPENLLL----DNNCDVKIADFGLSNVM 567 +VHRD+KPENLL+ D +K+ DFGL+ V+ Sbjct: 508 LSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVV 543
>CHK1_HUMAN (O14757) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 112 bits (280), Expect = 8e-25 Identities = 58/153 (37%), Positives = 98/153 (64%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 ++++ + +TLG G++G+V++A + T VA+KI++ ++ +D E +K+EI I ++ Sbjct: 6 VEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRA--VDCPENIKKEICINKMLN 63 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 H ++++ Y Y+ +EY GELFD I + E +A+RFF Q+++GV Y H Sbjct: 64 HENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHG 123 Query: 472 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMR 570 + HRD+KPENLLLD ++KI+DFGL+ V R Sbjct: 124 IGITHRDIKPENLLLDERDNLKISDFGLATVFR 156
>KAPCA_SHEEP (Q9MZD9) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 112 bits (280), Expect = 8e-25 Identities = 54/142 (38%), Positives = 89/142 (62%) Frame = +1 Query: 133 KTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPHIIRL 312 KTLG GSFG+V + +H +TG+ A+KIL+++K+ + E E +IL+ P +++L Sbjct: 47 KTLGTGSFGRVMLVKHTETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKL 106 Query: 313 YEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMVVHRD 492 + +++Y+VMEYV GE+F ++ GR E AR + QI+ +Y H +++RD Sbjct: 107 EFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRD 166 Query: 493 LKPENLLLDNNCDVKIADFGLS 558 LKPENLL+D +++ DFG + Sbjct: 167 LKPENLLIDQQGYIQVTDFGFA 188
>KAPCA_PIG (P36887) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 112 bits (279), Expect = 1e-24 Identities = 54/142 (38%), Positives = 89/142 (62%) Frame = +1 Query: 133 KTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPHIIRL 312 KTLG GSFG+V + +H +TG+ A+KIL+++K+ + E E +IL+ P +++L Sbjct: 47 KTLGTGSFGRVMLVKHKETGNHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKL 106 Query: 313 YEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMVVHRD 492 + +++Y+VMEYV GE+F ++ GR E AR + QI+ +Y H +++RD Sbjct: 107 EYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRD 166 Query: 493 LKPENLLLDNNCDVKIADFGLS 558 LKPENLL+D +++ DFG + Sbjct: 167 LKPENLLIDQQGYIQVTDFGFA 188
>CDPK3_ORYSA (P53684) Calcium-dependent protein kinase, isoform 11 (EC 2.7.11.1)| (CDPK 11) Length = 542 Score = 112 bits (279), Expect = 1e-24 Identities = 65/166 (39%), Positives = 95/166 (57%), Gaps = 4/166 (2%) Frame = +1 Query: 91 GGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREI 270 G K + ++Y IG+ LG G FG + I TG + A K + +RK+ + E V+REI Sbjct: 69 GRKTADLREHYIIGRKLGQGQFGTTYLCTEINTGCEYACKTIPKRKLITKEDVEDVRREI 128 Query: 271 KILR-LFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQII 447 +I+ L H +++ + +V E +++VME GELFD I EKG E++A + I+ Sbjct: 129 QIMHHLSGHKNVVAIKDVYEDGQAVHIVMELCAGGELFDRIQEKGHYSERKAAELIRIIV 188 Query: 448 SGVQYCHRNMVVHRDLKPENLLL---DNNCDVKIADFGLSNVMRDG 576 S V CH V+HRDLKPEN LL D++ +K DFGLS + G Sbjct: 189 SIVAMCHSLGVMHRDLKPENFLLLDKDDDLSIKAIDFGLSVFFKPG 234
>STK6_HUMAN (O14965) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1) (Aurora-related kinase 1) (hARK1) (Aurora-A) (Breast-tumor-amplified kinase) Length = 403 Score = 112 bits (279), Expect = 1e-24 Identities = 53/160 (33%), Positives = 94/160 (58%) Frame = +1 Query: 79 KMEAGGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKV 258 K E K L+++ IG+ LG G FG V +A ++ +A+K+L + +++ +E ++ Sbjct: 119 KNEESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQL 178 Query: 259 KREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQ 438 +RE++I HP+I+RLY +Y+++EY G ++ + + + EQ + Sbjct: 179 RREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYIT 238 Query: 439 QIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLS 558 ++ + + YCH V+HRD+KPENLLL + ++KIADFG S Sbjct: 239 ELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS 278
>KAPCA_CANFA (Q8MJ44) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 349 Score = 111 bits (278), Expect = 1e-24 Identities = 54/142 (38%), Positives = 89/142 (62%) Frame = +1 Query: 133 KTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPHIIRL 312 KTLG GSFG+V + +H +TG+ A+KIL+++K+ + E E +IL+ P +++L Sbjct: 46 KTLGTGSFGRVMLVKHKETGNHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKL 105 Query: 313 YEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMVVHRD 492 + +++Y+VMEYV GE+F ++ GR E AR + QI+ +Y H +++RD Sbjct: 106 EFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRD 165 Query: 493 LKPENLLLDNNCDVKIADFGLS 558 LKPENLL+D +++ DFG + Sbjct: 166 LKPENLLIDQQGYIQVTDFGFA 187
>KAPCB_PIG (P05383) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 111 bits (278), Expect = 1e-24 Identities = 58/162 (35%), Positives = 96/162 (59%) Frame = +1 Query: 73 RWKMEAGGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEE 252 +W+ A G L+++ KTLG GSFG+V + +H T A+KIL+++K+ + E Sbjct: 29 KWENPAPNNAG--LEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIE 86 Query: 253 KVKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRF 432 E +IL+ P ++RL + +++Y+VMEYV GE+F ++ GR E AR + Sbjct: 87 HTLNEKRILQAVNFPFLVRLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFY 146 Query: 433 FQQIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLS 558 QI+ +Y H +++RDLKPENLL+D+ +++ DFG + Sbjct: 147 AAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFA 188
>KAPCB_HUMAN (P22694) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 111 bits (278), Expect = 1e-24 Identities = 57/160 (35%), Positives = 95/160 (59%) Frame = +1 Query: 79 KMEAGGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKV 258 K E ++ L+++ KTLG GSFG+V + +H T A+KIL+++K+ + E Sbjct: 29 KWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHT 88 Query: 259 KREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQ 438 E +IL+ P ++RL + +++Y+VMEYV GE+F ++ GR E AR + Sbjct: 89 LNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAA 148 Query: 439 QIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLS 558 QI+ +Y H +++RDLKPENLL+D+ +++ DFG + Sbjct: 149 QIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFA 188
>KCC1_METAN (O14408) Calcium/calmodulin-dependent protein kinase (EC 2.7.11.17)| Length = 382 Score = 111 bits (278), Expect = 1e-24 Identities = 60/152 (39%), Positives = 94/152 (61%), Gaps = 3/152 (1%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 Y+ G+TLG G++G V+ A+ KVAIKI+ ++ +K E+ V E+ +L+ HPH Sbjct: 23 YKFGRTLGAGTYGVVREADG--PSGKVAIKIILKKNVKGN--EKMVYAELDMLQRLTHPH 78 Query: 301 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 480 I++ + E+ Y+V + GELFD I ++G+ E +A + +QI++ V Y H N V Sbjct: 79 IVKFVDWFESRDKFYIVTQLATGGELFDRICDQGKFTEVDASQTIRQIMTAVDYLHDNDV 138 Query: 481 VHRDLKPENLLL---DNNCDVKIADFGLSNVM 567 VHRDLKPENLL D + D+ +ADFG++ + Sbjct: 139 VHRDLKPENLLYVTRDPDSDLVLADFGITKTL 170
>KCC2_YEAST (P22517) Calcium/calmodulin-dependent protein kinase II (EC| 2.7.11.17) Length = 447 Score = 111 bits (278), Expect = 1e-24 Identities = 59/155 (38%), Positives = 91/155 (58%), Gaps = 4/155 (2%) Frame = +1 Query: 118 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDME-EKVKREIKILRLFMH 294 NY G+TLG GSFG V+ A + T VAIKIL ++ ++ +++ + + E+ IL+ H Sbjct: 46 NYIFGRTLGAGSFGVVRQARKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLSH 105 Query: 295 PHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRN 474 P+I+ + E+ Y+V + GELFD I+ +G+ E +A QI+ V+Y H Sbjct: 106 PNIVSFKDWFESKDKFYIVTQLATGGELFDRILSRGKFTEVDAVEIIVQILGAVEYMHSK 165 Query: 475 MVVHRDLKPENLLL---DNNCDVKIADFGLSNVMR 570 VVHRDLKPEN+L N + IADFG++ ++ Sbjct: 166 NVVHRDLKPENVLYVDKSENSPLVIADFGIAKQLK 200
>TSSK3_HUMAN (Q96PN8) Testis-specific serine/threonine-protein kinase 3 (EC| 2.7.11.1) (TSSK-3) (Testis-specific kinase 3) (TSK-3) (Serine/threonine-protein kinase 22C) Length = 268 Score = 111 bits (277), Expect = 2e-24 Identities = 59/154 (38%), Positives = 96/154 (62%), Gaps = 1/154 (0%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 Y++GKT+G G++ KVK A K KVAIK++++ ++ + RE++I+R H + Sbjct: 10 YQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRFLPRELQIVRTLDHKN 69 Query: 301 IIRLYEVIE-APADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 477 II++YE++E A I +VME + G++FD ++ G L E A+ F+Q++ ++YCH Sbjct: 70 IIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGCG 129 Query: 478 VVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGH 579 V HRDLK EN LL ++K+ DFG + V+ H Sbjct: 130 VAHRDLKCENALL-QGFNLKLTDFGFAKVLPKSH 162
>CDPK1_PLAYO (Q7RAH3) Calcium-dependent protein kinase 1 (EC 2.7.11.1)| Length = 534 Score = 111 bits (277), Expect = 2e-24 Identities = 61/169 (36%), Positives = 105/169 (62%), Gaps = 14/169 (8%) Frame = +1 Query: 97 KDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGH-KVAIKILNRRKI---------KNMD- 243 K+G ++Y + LG G++G+V + + K GH + AIK++ + + KN++ Sbjct: 48 KEGKIGESYFKVRKLGSGAYGEVLLCKE-KNGHSEKAIKVIKKSQFDKGRYNDDNKNIEK 106 Query: 244 MEEKVKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEA 423 E++ EI +L+ HP+II+L++V E Y+V E+ + GELF+ I+ + + E +A Sbjct: 107 FHEEIYNEISLLKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQIINRHKFDECDA 166 Query: 424 RRFFQQIISGVQYCHRNMVVHRDLKPENLLLDNN---CDVKIADFGLSN 561 +QI+SG+ Y H++ +VHRD+KPEN+LL+N ++KI DFGLS+ Sbjct: 167 ANIMKQILSGICYLHKHNIVHRDIKPENILLENKNSLLNIKIVDFGLSS 215
>IPL1_ASHGO (Q755C4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 367 Score = 111 bits (277), Expect = 2e-24 Identities = 54/171 (31%), Positives = 96/171 (56%), Gaps = 5/171 (2%) Frame = +1 Query: 79 KMEAGGKDGNPLKN-----YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMD 243 K AGG + L+N + IGK LG G FG+V HI++G A+K + ++ I + Sbjct: 90 KARAGGVPLSKLQNLKLADFEIGKVLGKGKFGRVYCVRHIESGFVCALKAMEKKDIIQYN 149 Query: 244 MEEKVKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEA 423 +E++ +RE++I HP++ +LY +Y++MEY+ +GEL+ ++ + + A Sbjct: 150 IEKQFRREVEIQSSLRHPNLTQLYGYFHDEKRVYLLMEYLVNGELYKHLKGRSHFNDVVA 209 Query: 424 RRFFQQIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDG 576 + Q+ + Y H ++HRD+KPEN+++ N +K+ DFG S + G Sbjct: 210 SYYVYQMADALDYMHERNILHRDIKPENIIIGFNNTIKLTDFGWSVITPKG 260
>KAPC_DICDI (P34099) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) Length = 648 Score = 111 bits (277), Expect = 2e-24 Identities = 53/157 (33%), Positives = 90/157 (57%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 LK ++ + LG G+FGKV + ++ K G A+K LN+ + + E + E IL Sbjct: 333 LKEFKQIRVLGTGTFGKVYLIQNTKDGCYYAMKCLNKAYVVQLKQVEHLNSEKSILSSIH 392 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 HP I+ LY+ + +Y++ EYV GE+F ++ + + A+ + +I+ +++ H+ Sbjct: 393 HPFIVNLYQAFQDEKKLYLLFEYVAGGEVFTHLRKSMKFSNSTAKFYAAEIVLALEFLHK 452 Query: 472 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHF 582 +V+RDLKPENLL+DN +KI DFG + + D F Sbjct: 453 QNIVYRDLKPENLLIDNQGHIKITDFGFAKRVEDRTF 489
>KCC2A_MOUSE (P11798) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 110 bits (276), Expect = 2e-24 Identities = 60/151 (39%), Positives = 91/151 (60%), Gaps = 3/151 (1%) Frame = +1 Query: 115 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 294 + Y++ + LG G+F V+ + G + KI+N +K+ D +K++RE +I RL H Sbjct: 11 EEYQLFEELGKGAFSVVRRCVKVLAGQEYPAKIINTKKLSARD-HQKLEREARICRLLKH 69 Query: 295 PHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRN 474 P+I+RL++ I Y++ + V GELF+ IV + E +A QQI+ V +CH+ Sbjct: 70 PNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQM 129 Query: 475 MVVHRDLKPENLLLDN---NCDVKIADFGLS 558 VVHRDLKPENLLL + VK+ADFGL+ Sbjct: 130 GVVHRDLKPENLLLASKLKGAAVKLADFGLA 160
>RAD53_YEAST (P22216) Serine/threonine-protein kinase RAD53 (EC 2.7.11.1)| (Serine-protein kinase 1) Length = 821 Score = 110 bits (276), Expect = 2e-24 Identities = 62/156 (39%), Positives = 93/156 (59%), Gaps = 3/156 (1%) Frame = +1 Query: 127 IGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRK-IKNMDMEEKVKREIKILRLFMHPHI 303 I + +G G+F VK A TG A+KI+++RK I NMD V RE+++L+ HP I Sbjct: 200 IDEVVGQGAFATVKKAIERTTGKTFAVKIISKRKVIGNMD---GVTRELEVLQKLNHPRI 256 Query: 304 IRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMVV 483 +RL E Y+VME+V G+L D++ G + E R +QI++ ++Y H + Sbjct: 257 VRLKGFYEDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGREISRQILTAIKYIHSMGIS 316 Query: 484 HRDLKPENLLL--DNNCDVKIADFGLSNVMRDGHFL 585 HRDLKP+N+L+ D+ VKI DFGL+ V +G F+ Sbjct: 317 HRDLKPDNILIEQDDPVLVKITDFGLAKVQGNGSFM 352
>KAPCB_RAT (P68182) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 110 bits (275), Expect = 3e-24 Identities = 55/149 (36%), Positives = 91/149 (61%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 L+++ KTLG GSFG+V + +H T A+KIL+++K+ + E E +IL+ Sbjct: 40 LEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVE 99 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 P ++RL + +++Y+VMEYV GE+F ++ GR E AR + QI+ +Y H Sbjct: 100 FPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS 159 Query: 472 NMVVHRDLKPENLLLDNNCDVKIADFGLS 558 +++RDLKPENLL+D+ +++ DFG + Sbjct: 160 LDLIYRDLKPENLLIDHQGYIQVTDFGFA 188
>KAPCB_MOUSE (P68181) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 110 bits (275), Expect = 3e-24 Identities = 55/149 (36%), Positives = 91/149 (61%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 L+++ KTLG GSFG+V + +H T A+KIL+++K+ + E E +IL+ Sbjct: 40 LEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVE 99 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 P ++RL + +++Y+VMEYV GE+F ++ GR E AR + QI+ +Y H Sbjct: 100 FPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS 159 Query: 472 NMVVHRDLKPENLLLDNNCDVKIADFGLS 558 +++RDLKPENLL+D+ +++ DFG + Sbjct: 160 LDLIYRDLKPENLLIDHQGYIQVTDFGFA 188
>KAPCB_CRIGR (P68180) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 110 bits (275), Expect = 3e-24 Identities = 55/149 (36%), Positives = 91/149 (61%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 L+++ KTLG GSFG+V + +H T A+KIL+++K+ + E E +IL+ Sbjct: 40 LEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVE 99 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 P ++RL + +++Y+VMEYV GE+F ++ GR E AR + QI+ +Y H Sbjct: 100 FPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS 159 Query: 472 NMVVHRDLKPENLLLDNNCDVKIADFGLS 558 +++RDLKPENLL+D+ +++ DFG + Sbjct: 160 LDLIYRDLKPENLLIDHQGYIQVTDFGFA 188
>KAPCA_MOUSE (P05132) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 110 bits (275), Expect = 3e-24 Identities = 56/160 (35%), Positives = 95/160 (59%) Frame = +1 Query: 79 KMEAGGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKV 258 K E ++ L + KTLG GSFG+V + +H ++G+ A+KIL+++K+ + E Sbjct: 29 KWETPSQNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHT 88 Query: 259 KREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQ 438 E +IL+ P +++L + +++Y+VMEYV GE+F ++ GR E AR + Sbjct: 89 LNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAA 148 Query: 439 QIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLS 558 QI+ +Y H +++RDLKPENLL+D +++ DFG + Sbjct: 149 QIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFA 188
>PHKG2_HUMAN (P15735) Phosphorylase b kinase gamma catalytic chain, testis/liver| isoform (EC 2.7.11.19) (PHK-gamma-T) (Phosphorylase kinase gamma subunit 2) (PSK-C3) Length = 406 Score = 110 bits (275), Expect = 3e-24 Identities = 59/155 (38%), Positives = 92/155 (59%), Gaps = 6/155 (3%) Frame = +1 Query: 139 LGIGSFGKVKIAEHIKTGHKVAIKILN----RRKIKNMD-MEEKVKREIKILRLFM-HPH 300 +G G V+ H TGH+ A+KI+ R + ++ + E +RE ILR HPH Sbjct: 30 IGRGVSSVVRRCVHRATGHEFAVKIMEVTAERLSPEQLEEVREATRRETHILRQVAGHPH 89 Query: 301 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 480 II L + E+ + +++V + ++ GELFDY+ EK L E+E R + ++ V + H N + Sbjct: 90 IITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHANNI 149 Query: 481 VHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFL 585 VHRDLKPEN+LLD+N ++++DFG S + G L Sbjct: 150 VHRDLKPENILLDDNMQIRLSDFGFSCHLEPGEKL 184
>KAPCA_RAT (P27791) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 110 bits (274), Expect = 4e-24 Identities = 53/142 (37%), Positives = 89/142 (62%) Frame = +1 Query: 133 KTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPHIIRL 312 KTLG GSFG+V + +H ++G+ A+KIL+++K+ + E E +IL+ P +++L Sbjct: 47 KTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKL 106 Query: 313 YEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMVVHRD 492 + +++Y+VMEYV GE+F ++ GR E AR + QI+ +Y H +++RD Sbjct: 107 EFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRD 166 Query: 493 LKPENLLLDNNCDVKIADFGLS 558 LKPENLL+D +++ DFG + Sbjct: 167 LKPENLLIDQQGYIQVTDFGFA 188
>DCAK2_HUMAN (Q8N568) Serine/threonine-protein kinase DCAMKL2 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 2) Length = 766 Score = 110 bits (274), Expect = 4e-24 Identities = 59/156 (37%), Positives = 91/156 (58%), Gaps = 4/156 (2%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 L+ Y+IGK +G G+F VK TG + A+KI++ K K E ++ E+ ILR Sbjct: 391 LEKYKIGKVIGDGNFAVVKECIDRSTGKEFALKIID--KAKCCGKEHLIENEVSILRRVK 448 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 HP+II L E +E ++++VME VK G+LFD I + E++ + + ++Y H Sbjct: 449 HPNIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHG 508 Query: 472 NMVVHRDLKPENLLL----DNNCDVKIADFGLSNVM 567 +VHRD+KPENLL+ D +K+ DFGL+ V+ Sbjct: 509 LSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVV 544
>CDPK1_PLAFK (P62343) Calcium-dependent protein kinase 1 (EC 2.7.11.1) (PfCPK)| (PfCDPK1) Length = 523 Score = 109 bits (273), Expect = 5e-24 Identities = 60/171 (35%), Positives = 102/171 (59%), Gaps = 16/171 (9%) Frame = +1 Query: 97 KDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGH-KVAIKILNRRKIKNMD---------- 243 K+G ++Y + LG G++G+V + K GH + AIK++ + + M Sbjct: 47 KEGKIGESYFKVRKLGSGAYGEVLLCRE-KHGHGEKAIKVIKKSQFDKMKYSITNKIECD 105 Query: 244 --MEEKVKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQ 417 + E++ EI +L+ HP+II+L++V E Y+V E+ + GELF+ I+ + + E Sbjct: 106 DKIHEEIYNEISLLKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQIINRHKFDEC 165 Query: 418 EARRFFQQIISGVQYCHRNMVVHRDLKPENLLLDNN---CDVKIADFGLSN 561 +A +QI+SG+ Y H++ +VHRD+KPEN+LL+N ++KI DFGLS+ Sbjct: 166 DAANIMKQILSGICYLHKHNIVHRDIKPENILLENKHSLLNIKIVDFGLSS 216
>CDPK1_PLAF7 (P62344) Calcium-dependent protein kinase 1 (EC 2.7.11.1)| Length = 523 Score = 109 bits (273), Expect = 5e-24 Identities = 60/171 (35%), Positives = 102/171 (59%), Gaps = 16/171 (9%) Frame = +1 Query: 97 KDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGH-KVAIKILNRRKIKNMD---------- 243 K+G ++Y + LG G++G+V + K GH + AIK++ + + M Sbjct: 47 KEGKIGESYFKVRKLGSGAYGEVLLCRE-KHGHGEKAIKVIKKSQFDKMKYSITNKIECD 105 Query: 244 --MEEKVKREIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQ 417 + E++ EI +L+ HP+II+L++V E Y+V E+ + GELF+ I+ + + E Sbjct: 106 DKIHEEIYNEISLLKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQIINRHKFDEC 165 Query: 418 EARRFFQQIISGVQYCHRNMVVHRDLKPENLLLDNN---CDVKIADFGLSN 561 +A +QI+SG+ Y H++ +VHRD+KPEN+LL+N ++KI DFGLS+ Sbjct: 166 DAANIMKQILSGICYLHKHNIVHRDIKPENILLENKHSLLNIKIVDFGLSS 216
>IPL1_DEBHA (Q6BVA0) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 412 Score = 109 bits (273), Expect = 5e-24 Identities = 50/149 (33%), Positives = 89/149 (59%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 L ++ IGK LG G GKV +H +G+ A+K++ ++ + ++ +E+ +REI+I + Sbjct: 145 LDDFEIGKVLGKGKLGKVYCVKHKTSGYIAALKVMAKKDLIDLKLEKNFRREIEIQSNLI 204 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 HP I RLY ++Y+++EY GEL+ ++ + R + A + Q+ + Y H Sbjct: 205 HPKISRLYGFFYDHKNVYLILEYSIHGELYHHLKVQRRFNDATASHYIYQVALALDYLHT 264 Query: 472 NMVVHRDLKPENLLLDNNCDVKIADFGLS 558 ++HRD+KPEN+LL + +K++DFG S Sbjct: 265 KHIIHRDIKPENILLSTDNCIKLSDFGWS 293
>KCC4_MOUSE (P08414) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) Length = 469 Score = 109 bits (273), Expect = 5e-24 Identities = 66/162 (40%), Positives = 94/162 (58%), Gaps = 4/162 (2%) Frame = +1 Query: 94 GKDGNPLKNY-RIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREI 270 G + +PL ++ + LG G+ V + T A+K+L + K + V+ EI Sbjct: 32 GSNRDPLGDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKKI-----VRTEI 86 Query: 271 KILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIIS 450 +L HP+II+L E+ E P +I +V+E V GELFD IVEKG E++AR +QI+ Sbjct: 87 GVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDARDAVKQILE 146 Query: 451 GVQYCHRNMVVHRDLKPENLLLDN---NCDVKIADFGLSNVM 567 V Y H N +VHRDLKPENLL + +KIADFGLS ++ Sbjct: 147 AVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIV 188
>PDPK1_HUMAN (O15530) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (hPDK1) Length = 556 Score = 109 bits (272), Expect = 7e-24 Identities = 54/151 (35%), Positives = 86/151 (56%) Frame = +1 Query: 115 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 294 ++++ GK LG GSF V +A + T + AIKIL +R I + V RE ++ H Sbjct: 80 EDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDH 139 Query: 295 PHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRN 474 P ++LY + +Y + Y K+GEL YI + G E R + +I+S ++Y H Sbjct: 140 PFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGK 199 Query: 475 MVVHRDLKPENLLLDNNCDVKIADFGLSNVM 567 ++HRDLKPEN+LL+ + ++I DFG + V+ Sbjct: 200 GIIHRDLKPENILLNEDMHIQITDFGTAKVL 230
>IPL1_CANGA (Q6FV07) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 358 Score = 109 bits (272), Expect = 7e-24 Identities = 54/155 (34%), Positives = 91/155 (58%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 LK++ +G+ LG G FGKV H K+G A+K + + +I ++ +++KRE+ I Sbjct: 97 LKDFEVGRKLGKGKFGKVYCVRHKKSGFICALKAIEKNEILQFNLLKQLKREVDIQLGMD 156 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 HP+II+LY +Y++ME+ +GEL+ + G + A + QI + Y H+ Sbjct: 157 HPNIIKLYAHFHDEKRVYLLMEHSINGELYKSLKNNGPFNDVLASHYIYQIADALHYMHK 216 Query: 472 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDG 576 ++HRD+KPEN+L+ + VK+ADFG S + +G Sbjct: 217 KRIIHRDVKPENVLIGFDNVVKLADFGWSILNPEG 251
>PDPK1_RAT (O55173) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (Protein kinase B kinase) (PkB kinase) Length = 559 Score = 109 bits (272), Expect = 7e-24 Identities = 54/151 (35%), Positives = 86/151 (56%) Frame = +1 Query: 115 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 294 ++++ GK LG GSF V +A + T + AIKIL +R I + V RE ++ H Sbjct: 83 EDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDH 142 Query: 295 PHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRN 474 P ++LY + +Y + Y K+GEL YI + G E R + +I+S ++Y H Sbjct: 143 PFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGK 202 Query: 475 MVVHRDLKPENLLLDNNCDVKIADFGLSNVM 567 ++HRDLKPEN+LL+ + ++I DFG + V+ Sbjct: 203 GIIHRDLKPENILLNEDMHIQITDFGTAKVL 233
>PDPK1_MOUSE (Q9Z2A0) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (mPDK1) Length = 559 Score = 109 bits (272), Expect = 7e-24 Identities = 54/151 (35%), Positives = 86/151 (56%) Frame = +1 Query: 115 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMH 294 ++++ GK LG GSF V +A + T + AIKIL +R I + V RE ++ H Sbjct: 83 EDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDH 142 Query: 295 PHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRN 474 P ++LY + +Y + Y K+GEL YI + G E R + +I+S ++Y H Sbjct: 143 PFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGK 202 Query: 475 MVVHRDLKPENLLLDNNCDVKIADFGLSNVM 567 ++HRDLKPEN+LL+ + ++I DFG + V+ Sbjct: 203 GIIHRDLKPENILLNEDMHIQITDFGTAKVL 233
>KDC2_DROME (P16912) Protein kinase DC2 (EC 2.7.11.1)| Length = 583 Score = 108 bits (271), Expect = 9e-24 Identities = 56/154 (36%), Positives = 91/154 (59%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 L +Y+I KT+G G+FG+V + + A+KIL ++ + E VK E ILR Sbjct: 271 LDDYQIIKTVGTGTFGRVCLCRDRISEKYCAMKILAMTEVIRLKQIEHVKNERNILREIR 330 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 HP +I L + +++Y++ +YV GELF Y+ G+ Q + + +I+S ++Y H Sbjct: 331 HPFVISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGKFTSQTSNFYAAEIVSALEYLHS 390 Query: 472 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRD 573 +V+RDLKPENLL++ + +KI DFG + +RD Sbjct: 391 LQIVYRDLKPENLLINRDGHLKITDFGFAKKLRD 424
>KAPL_APLCA (P21901) Spermatozoon-associated protein kinase (EC 2.7.11.1) (SAK)| (C-APL-B) Length = 351 Score = 108 bits (271), Expect = 9e-24 Identities = 59/158 (37%), Positives = 92/158 (58%), Gaps = 2/158 (1%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHK--VAIKILNRRKIKNMDMEEKVKREIKILRL 285 ++NY + +TLG GSFG+V +++H + AIKILN+ K+ M E E +IL Sbjct: 39 IRNYTLIRTLGSGSFGRVMLSQHGGDNPQKCYAIKILNKEKVVKMKQVEHTMNEKRILLS 98 Query: 286 FMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYC 465 P ++R + ++Y+VME+V GELF + +KGRL E + Q+ +QY Sbjct: 99 IGSPFVVRCLNAFKDTTNLYMVMEFVNGGELFHLLRKKGRLPEYWCTFYAAQVTMALQYL 158 Query: 466 HRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGH 579 H +++RDLKPEN+LLD+ +K+ DFG ++ GH Sbjct: 159 HNCSLLYRDLKPENILLDHLGYLKVTDFGFDRRVQ-GH 195
>IPL1_YARLI (Q6C3J2) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 371 Score = 108 bits (271), Expect = 9e-24 Identities = 52/149 (34%), Positives = 89/149 (59%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 L ++ IGK LG G FGKV + + KTG A+K + ++++ ++E++ +RE++I Sbjct: 96 LDDFEIGKALGKGKFGKVYLVKDKKTGFVSALKCMEKKELVEGNVEKQFRREVEIQSNLR 155 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 H +++RL+ +Y+++EYV GEL+ + + R E A + Q+ + Y H Sbjct: 156 HTNVLRLFGHFHDKDRVYLILEYVVHGELYKLLRNQKRFTESTASSYIYQMSEALLYLHG 215 Query: 472 NMVVHRDLKPENLLLDNNCDVKIADFGLS 558 ++HRD+KPEN+LL N +KI+DFG S Sbjct: 216 KNIIHRDIKPENILLHFNDTIKISDFGWS 244
>KCC1_EMENI (Q00771) Calcium/calmodulin-dependent protein kinase (EC 2.7.11.17)| (CMPK) Length = 414 Score = 108 bits (270), Expect = 1e-23 Identities = 57/152 (37%), Positives = 92/152 (60%), Gaps = 3/152 (1%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 YR G+TLG G++G V+ A+ + KVA+KI+ +R ++ E V E+ +L+ HPH Sbjct: 23 YRFGRTLGAGTYGIVREADC--SSGKVAVKIILKRNVRGN--ERMVYDELDLLQKLNHPH 78 Query: 301 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 480 I+ + E+ Y+V + GELFD I E G+ E++A + +Q++ V Y H+ + Sbjct: 79 IVHFVDWFESKDKFYIVTQLATGGELFDRICEYGKFTEKDASQTIRQVLDAVNYLHQRNI 138 Query: 481 VHRDLKPENLLL---DNNCDVKIADFGLSNVM 567 VHRDLKPENLL D + + +ADFG++ ++ Sbjct: 139 VHRDLKPENLLYLTRDLDSQLVLADFGIAKML 170
>KPSH1_MOUSE (Q91YA2) Serine/threonine-protein kinase H1 (EC 2.7.11.1) (PSK-H1)| Length = 423 Score = 108 bits (269), Expect = 1e-23 Identities = 61/155 (39%), Positives = 87/155 (56%), Gaps = 3/155 (1%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 Y I +G GSF +V EH T AIK++ + K + E + E+++LR H + Sbjct: 97 YDIKALIGRGSFSRVVRVEHRATRQPYAIKMI---ETKYREGREVCESELRVLRRVRHAN 153 Query: 301 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 480 II+L EV E +Y+VME GELFD I+ KG E++A R Q ++ GV+Y H + Sbjct: 154 IIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGI 213 Query: 481 VHRDLKPENLLL---DNNCDVKIADFGLSNVMRDG 576 HRDLKPENLL + + I DFGL++ + G Sbjct: 214 THRDLKPENLLYYHPGTDSKIIITDFGLASARKKG 248
>KPSH1_HUMAN (P11801) Serine/threonine-protein kinase H1 (EC 2.7.11.1) (PSK-H1)| Length = 423 Score = 108 bits (269), Expect = 1e-23 Identities = 61/155 (39%), Positives = 87/155 (56%), Gaps = 3/155 (1%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 Y I +G GSF +V EH T AIK++ + K + E + E+++LR H + Sbjct: 97 YDIKALIGRGSFSRVVRVEHRATRQPYAIKMI---ETKYREGREVCESELRVLRRVRHAN 153 Query: 301 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 480 II+L EV E +Y+VME GELFD I+ KG E++A R Q ++ GV+Y H + Sbjct: 154 IIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGI 213 Query: 481 VHRDLKPENLLL---DNNCDVKIADFGLSNVMRDG 576 HRDLKPENLL + + I DFGL++ + G Sbjct: 214 THRDLKPENLLYYHPGTDSKIIITDFGLASARKKG 248
>PHKG2_MOUSE (Q9DB30) Phosphorylase b kinase gamma catalytic chain, testis/liver| isoform (EC 2.7.11.19) (PHK-gamma-T) (Phosphorylase kinase gamma subunit 2) Length = 406 Score = 108 bits (269), Expect = 1e-23 Identities = 57/155 (36%), Positives = 93/155 (60%), Gaps = 6/155 (3%) Frame = +1 Query: 139 LGIGSFGKVKIAEHIKTGHKVAIKILN----RRKIKNMD-MEEKVKREIKILRLFM-HPH 300 +G G V+ H TG + A+KI+ R ++ ++ + + +RE+ ILR HPH Sbjct: 30 IGRGVSSVVRRCVHRATGDEFAVKIMEVSAERLSLEQLEEVRDATRREMHILRQVAGHPH 89 Query: 301 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 480 II L + E+ + +++V + ++ GELFDY+ EK L E+E R + ++ V + H N + Sbjct: 90 IITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHANNI 149 Query: 481 VHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFL 585 VHRDLKPEN+LLD+N ++++DFG S + G L Sbjct: 150 VHRDLKPENILLDDNMQIRLSDFGFSCHLEAGEKL 184
>KAPC_DROME (P12370) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) (PKA C) Length = 352 Score = 108 bits (269), Expect = 1e-23 Identities = 53/142 (37%), Positives = 87/142 (61%) Frame = +1 Query: 133 KTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPHIIRL 312 KTLG GSFG+V I +H T A+KIL+++K+ + E E +IL+ P ++ L Sbjct: 49 KTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVSL 108 Query: 313 YEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMVVHRD 492 + +++Y+V+EYV GE+F ++ + GR E +R + QI+ +Y H +++RD Sbjct: 109 RYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRD 168 Query: 493 LKPENLLLDNNCDVKIADFGLS 558 LKPENLL+D+ +K+ DFG + Sbjct: 169 LKPENLLIDSQGYLKVTDFGFA 190
>PHKG2_RAT (P31325) Phosphorylase b kinase gamma catalytic chain, testis/liver| isoform (EC 2.7.11.19) (PHK-gamma-T) (Phosphorylase kinase gamma subunit 2) Length = 406 Score = 107 bits (268), Expect = 2e-23 Identities = 57/155 (36%), Positives = 93/155 (60%), Gaps = 6/155 (3%) Frame = +1 Query: 139 LGIGSFGKVKIAEHIKTGHKVAIKILN----RRKIKNMD-MEEKVKREIKILRLFM-HPH 300 +G G V+ H TG + A+KI+ R ++ ++ + + +RE+ ILR HPH Sbjct: 30 IGRGVSSVVRRCVHRATGDEFAVKIMEVSAERLSLEQLEEVRDATRREMHILRQVAGHPH 89 Query: 301 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 480 II L + E+ + +++V + ++ GELFDY+ EK L E+E R + ++ V + H N + Sbjct: 90 IITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVNFLHVNNI 149 Query: 481 VHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFL 585 VHRDLKPEN+LLD+N ++++DFG S + G L Sbjct: 150 VHRDLKPENILLDDNMQIRLSDFGFSCHLEPGEKL 184
>KAPC_YEAST (P05986) cAMP-dependent protein kinase type 3 (EC 2.7.11.11) (PKA| 3) Length = 398 Score = 107 bits (268), Expect = 2e-23 Identities = 51/154 (33%), Positives = 87/154 (56%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 L +++I +TLG GSFG+V + G A+K L + I + E E ++L + Sbjct: 85 LSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVS 144 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 HP IIR++ + +++VM+Y++ GELF + + R A+ + ++ ++Y H Sbjct: 145 HPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHS 204 Query: 472 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRD 573 +++RDLKPEN+LLD N +KI DFG + + D Sbjct: 205 KDIIYRDLKPENILLDKNGHIKITDFGFAKYVPD 238
>KCC1G_MOUSE (Q91VB2) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 477 Score = 107 bits (267), Expect = 3e-23 Identities = 58/160 (36%), Positives = 92/160 (57%), Gaps = 3/160 (1%) Frame = +1 Query: 106 NPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRL 285 N K + + LG G+F +V + + TG A+K + + + ++ EI +L+ Sbjct: 18 NIRKTFIFMEVLGSGAFSEVFLVKQRVTGKLFALKCIKKSPAFR---DSSLENEIAVLKR 74 Query: 286 FMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYC 465 H +I+ L ++ E+ Y+VM+ V GELFD I+E+G E++A QQ++S V+Y Sbjct: 75 IKHENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYL 134 Query: 466 HRNMVVHRDLKPENLLL---DNNCDVKIADFGLSNVMRDG 576 H N +VHRDLKPENLL + N + I DFGLS + ++G Sbjct: 135 HENGIVHRDLKPENLLYLTPEENSKIMITDFGLSKMEQNG 174
>LOK_DROME (O61267) Ovarian-specific serine/threonine-protein kinase Lok (EC| 2.7.11.1) (Protein loki) (dMNK) Length = 476 Score = 107 bits (267), Expect = 3e-23 Identities = 49/161 (30%), Positives = 97/161 (60%), Gaps = 9/161 (5%) Frame = +1 Query: 115 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIK------NMDMEEKVKREIKI 276 K Y + + LG G++G V++ +T + A+KI+ + + N ++V E KI Sbjct: 172 KTYYVNRKLGSGAYGLVRLVYDTRTCQQFAMKIVKKNMLSGARPSTNFSDPDRVLNEAKI 231 Query: 277 LRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGV 456 ++ HP ++R++++++ P +Y+V+E+++ G+L + I+ L E ++ +F Q+ V Sbjct: 232 MKNLSHPCVVRMHDIVDKPDSVYMVLEFMRGGDLLNRIISNKLLSEDISKLYFYQMCHAV 291 Query: 457 QYCHRNMVVHRDLKPENLLLDNNCD---VKIADFGLSNVMR 570 +Y H + HRDLKP+N+LL+ N + +K++DFGLS ++ Sbjct: 292 KYLHDRGITHRDLKPDNVLLETNDEETLLKVSDFGLSKFVQ 332
>KCC1G_RAT (Q7TNJ7) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 476 Score = 107 bits (267), Expect = 3e-23 Identities = 58/160 (36%), Positives = 92/160 (57%), Gaps = 3/160 (1%) Frame = +1 Query: 106 NPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRL 285 N K + + LG G+F +V + + TG A+K + + + ++ EI +L+ Sbjct: 18 NIRKTFIFMEVLGSGAFSEVFLVKQRVTGKLFALKCIKKSPAFR---DSSLENEIAVLKR 74 Query: 286 FMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYC 465 H +I+ L ++ E+ Y+VM+ V GELFD I+E+G E++A QQ++S V+Y Sbjct: 75 IKHENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYL 134 Query: 466 HRNMVVHRDLKPENLLL---DNNCDVKIADFGLSNVMRDG 576 H N +VHRDLKPENLL + N + I DFGLS + ++G Sbjct: 135 HENGIVHRDLKPENLLYLTPEENSKIMITDFGLSKMEQNG 174
>KCC1G_HUMAN (Q96NX5) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 476 Score = 107 bits (267), Expect = 3e-23 Identities = 58/160 (36%), Positives = 92/160 (57%), Gaps = 3/160 (1%) Frame = +1 Query: 106 NPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRL 285 N K + + LG G+F +V + + TG A+K + + + ++ EI +L+ Sbjct: 18 NIRKTFIFMEVLGSGAFSEVFLVKQRLTGKLFALKCIKKSPAFR---DSSLENEIAVLKK 74 Query: 286 FMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYC 465 H +I+ L ++ E+ Y+VM+ V GELFD I+E+G E++A QQ++S V+Y Sbjct: 75 IKHENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYL 134 Query: 466 HRNMVVHRDLKPENLLL---DNNCDVKIADFGLSNVMRDG 576 H N +VHRDLKPENLL + N + I DFGLS + ++G Sbjct: 135 HENGIVHRDLKPENLLYLTPEENSKIMITDFGLSKMEQNG 174
>KCC2G_MOUSE (Q923T9) Calcium/calmodulin-dependent protein kinase type II gamma| chain (EC 2.7.11.17) (CaM-kinase II gamma chain) (CaM kinase II gamma subunit) (CaMK-II gamma subunit) Length = 529 Score = 107 bits (267), Expect = 3e-23 Identities = 59/150 (39%), Positives = 91/150 (60%), Gaps = 3/150 (2%) Frame = +1 Query: 118 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 297 +Y++ + LG G+F V+ + + A KI+N +K+ D +K++RE +I RL HP Sbjct: 13 DYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARD-HQKLEREARICRLLKHP 71 Query: 298 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 477 +I+RL++ I Y+V + V GELF+ IV + E +A QI+ V + H++ Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHD 131 Query: 478 VVHRDLKPENLLLDNNCD---VKIADFGLS 558 +VHRDLKPENLLL + C VK+ADFGL+ Sbjct: 132 IVHRDLKPENLLLASKCKGAAVKLADFGLA 161
>KCC2G_HUMAN (Q13555) Calcium/calmodulin-dependent protein kinase type II gamma| chain (EC 2.7.11.17) (CaM-kinase II gamma chain) (CaM kinase II gamma subunit) (CaMK-II gamma subunit) Length = 558 Score = 107 bits (267), Expect = 3e-23 Identities = 59/150 (39%), Positives = 91/150 (60%), Gaps = 3/150 (2%) Frame = +1 Query: 118 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 297 +Y++ + LG G+F V+ + + A KI+N +K+ D +K++RE +I RL HP Sbjct: 13 DYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARD-HQKLEREARICRLLKHP 71 Query: 298 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 477 +I+RL++ I Y+V + V GELF+ IV + E +A QI+ V + H++ Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHD 131 Query: 478 VVHRDLKPENLLLDNNCD---VKIADFGLS 558 +VHRDLKPENLLL + C VK+ADFGL+ Sbjct: 132 IVHRDLKPENLLLASKCKGAAVKLADFGLA 161
>KCC2G_RAT (P11730) Calcium/calmodulin-dependent protein kinase type II gamma| chain (EC 2.7.11.17) (CaM-kinase II gamma chain) (CaM kinase II gamma subunit) (CaMK-II gamma subunit) Length = 527 Score = 107 bits (267), Expect = 3e-23 Identities = 59/150 (39%), Positives = 91/150 (60%), Gaps = 3/150 (2%) Frame = +1 Query: 118 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 297 +Y++ + LG G+F V+ + + A KI+N +K+ D +K++RE +I RL HP Sbjct: 13 DYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARD-HQKLEREARICRLLKHP 71 Query: 298 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 477 +I+RL++ I Y+V + V GELF+ IV + E +A QI+ V + H++ Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHD 131 Query: 478 VVHRDLKPENLLLDNNCD---VKIADFGLS 558 +VHRDLKPENLLL + C VK+ADFGL+ Sbjct: 132 IVHRDLKPENLLLASKCKGAAVKLADFGLA 161
>KCC4_RAT (P13234) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) (Calspermin) Length = 474 Score = 107 bits (267), Expect = 3e-23 Identities = 65/162 (40%), Positives = 92/162 (56%), Gaps = 4/162 (2%) Frame = +1 Query: 94 GKDGNPLKNY-RIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREI 270 G +PL ++ + LG G+ V + T A+K+L + K + V+ EI Sbjct: 32 GSKRDPLSDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKKI-----VRTEI 86 Query: 271 KILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIIS 450 +L HP+II+L E+ E P +I +V+E V GELFD IVEKG E++A +QI+ Sbjct: 87 GVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILE 146 Query: 451 GVQYCHRNMVVHRDLKPENLLLDN---NCDVKIADFGLSNVM 567 V Y H N +VHRDLKPENLL + +KIADFGLS ++ Sbjct: 147 AVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIV 188
>KAPC_CAEEL (P21137) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) (PKA C) Length = 404 Score = 107 bits (266), Expect = 3e-23 Identities = 50/142 (35%), Positives = 89/142 (62%) Frame = +1 Query: 133 KTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPHIIRL 312 KTLG GSFG+V + +H ++G+ A+KIL+++K+ + E E +IL+ P ++ + Sbjct: 85 KTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNM 144 Query: 313 YEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMVVHRD 492 + +++Y+V+E++ GE+F ++ GR E +R + QI+ +Y H +++RD Sbjct: 145 TFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRD 204 Query: 493 LKPENLLLDNNCDVKIADFGLS 558 LKPENLL+D+ +KI DFG + Sbjct: 205 LKPENLLIDSTGYLKITDFGFA 226
>KAPA_YEAST (P06244) cAMP-dependent protein kinase type 1 (EC 2.7.11.11) (PKA| 1) (CDC25-suppressing protein kinase) (PK-25) Length = 397 Score = 107 bits (266), Expect = 3e-23 Identities = 50/154 (32%), Positives = 88/154 (57%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 L++++I +TLG GSFG+V + G A+K+L + + + E E +L + Sbjct: 84 LQDFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVT 143 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 HP IIR++ + I+++M+Y++ GELF + + R A+ + ++ ++Y H Sbjct: 144 HPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHS 203 Query: 472 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRD 573 +++RDLKPEN+LLD N +KI DFG + + D Sbjct: 204 KDIIYRDLKPENILLDKNGHIKITDFGFAKYVPD 237
>IPL1_YEAST (P38991) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) (Increase-in-ploidy protein 1) Length = 367 Score = 107 bits (266), Expect = 3e-23 Identities = 48/149 (32%), Positives = 88/149 (59%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 L ++ +GK LG G FGKV H TG+ A+K++ + +I +++++ +RE++I Sbjct: 101 LDDFELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKYNLQKQFRREVEIQTSLN 160 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 HP++ + Y +Y++MEY+ +GE++ + G + A + QI + + Y H+ Sbjct: 161 HPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALDYMHK 220 Query: 472 NMVVHRDLKPENLLLDNNCDVKIADFGLS 558 ++HRD+KPEN+L+ N +K+ DFG S Sbjct: 221 KNIIHRDIKPENILIGFNNVIKLTDFGWS 249
>PKN2_BACSU (O34507) Probable serine/threonine-protein kinase yloP (EC| 2.7.11.1) Length = 648 Score = 107 bits (266), Expect = 3e-23 Identities = 52/149 (34%), Positives = 87/149 (58%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 Y+I + +G G V +AE I +VAIKIL + + + +RE + HP+ Sbjct: 11 YQILRVIGGGGMANVYLAEDIILDREVAIKILRFDYANDNEFIRRFRREAQSASSLDHPN 70 Query: 301 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 480 I+ +Y++ E Y+VMEYV+ L +YI G L +EA +QI+S + + H+N + Sbjct: 71 IVSIYDLGEEDDIYYIVMEYVEGMTLKEYITANGPLHPKEALNIMEQIVSAIAHAHQNQI 130 Query: 481 VHRDLKPENLLLDNNCDVKIADFGLSNVM 567 VHRD+KP N+L+D+ ++K+ DFG++ + Sbjct: 131 VHRDIKPHNILIDHMGNIKVTDFGIATAL 159
>PIM1_BRARE (Q9YHZ5) Serine/threonine-protein kinase Pim-1 (EC 2.7.11.1)| Length = 310 Score = 106 bits (265), Expect = 4e-23 Identities = 63/171 (36%), Positives = 91/171 (53%), Gaps = 15/171 (8%) Frame = +1 Query: 115 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDME----EKVKREIKILR 282 K Y +G LG G FG V I G KVAIK ++R +I+ V EI +L+ Sbjct: 28 KQYTMGNLLGSGGFGSVYSGHRISDGQKVAIKQISRDRIQQWSKMPGEVNPVPNEIALLQ 87 Query: 283 LFM--------HPHIIRLYEVIEAPADIYVVM--EYVKSGELFDYIVEKGRLQEQEARRF 432 H IIR+ + E P Y+++ + +LFD+I E+GRL E ARRF Sbjct: 88 SLGGGSGSVPGHRGIIRMLDWFEIPGQEYLIVFEKPQHCQDLFDFITERGRLDESLARRF 147 Query: 433 FQQIISGVQYCHRNMVVHRDLKPENLLLDNNC-DVKIADFGLSNVMRDGHF 582 +Q+I VQ+CH +VHRD+K EN+L+D D+K+ DFG ++D + Sbjct: 148 LKQVIEAVQFCHSKGIVHRDIKDENILVDTRTGDIKVIDFGSGATLKDSMY 198
>DUN1_YEAST (P39009) DNA damage response protein kinase DUN1 (EC 2.7.11.1)| Length = 513 Score = 106 bits (265), Expect = 4e-23 Identities = 59/178 (33%), Positives = 97/178 (54%), Gaps = 24/178 (13%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 Y +GK LG G + VK A++ KTG +VA+KI + ++ + ++ + E IL HP+ Sbjct: 200 YLLGKELGAGHYALVKEAKNKKTGQQVAVKIFHAQQNDDQKKNKQFREETNILMRVQHPN 259 Query: 301 IIRLYEVIEAPADI-----YVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYC 465 I+ L + P Y+V+E + GELF+ IV K L++ E++ F+Q+++G++Y Sbjct: 260 IVNLLDSFVEPISKSQIQKYLVLEKIDDGELFERIVRKTCLRQDESKALFKQLLTGLKYL 319 Query: 466 HRNMVVHRDLKPENLLL-------------------DNNCDVKIADFGLSNVMRDGHF 582 H ++HRD+KPEN+LL + + VKIADFGL+ + F Sbjct: 320 HEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGEMQF 377
>STK33_HUMAN (Q9BYT3) Serine/threonine-protein kinase 33 (EC 2.7.11.1)| Length = 514 Score = 106 bits (264), Expect = 6e-23 Identities = 62/155 (40%), Positives = 89/155 (57%), Gaps = 9/155 (5%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 Y G+ LG GSFG V A +T K AIK +N+ K + ++ ++RE+ IL+ H H Sbjct: 116 YTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVK-LLEREVNILKSVKHEH 174 Query: 301 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 480 II L +V E P +Y+VME + GEL + + KG E E R Q + S + Y H N + Sbjct: 175 IIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDI 234 Query: 481 VHRDLKPENLLL------DN---NCDVKIADFGLS 558 VHRDLK EN+++ DN N ++K+ DFGL+ Sbjct: 235 VHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLA 269
>PRKX_HUMAN (P51817) Serine/threonine-protein kinase PRKX (EC 2.7.11.1)| (Protein kinase PKX1) Length = 358 Score = 106 bits (264), Expect = 6e-23 Identities = 51/154 (33%), Positives = 87/154 (56%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 L+++ T+G G+FG+V + + H A+K+++ + + E+ V E +L+ Sbjct: 46 LQDFDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQEQHVHNEKSVLKEVS 105 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 HP +IRL+ +Y++MEYV GELF Y+ +GR + +II ++Y H Sbjct: 106 HPFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGLFYSAEIICAIEYLHS 165 Query: 472 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRD 573 +V+RDLKPEN+LLD + +K+ DFG + + D Sbjct: 166 KEIVYRDLKPENILLDRDGHIKLTDFGFAKKLVD 199
>KPSH1_PINFU (Q4KTY1) Serine/threonine-protein kinase H1 homolog (EC 2.7.11.1)| Length = 415 Score = 106 bits (264), Expect = 6e-23 Identities = 61/153 (39%), Positives = 86/153 (56%), Gaps = 3/153 (1%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 Y I +G G+F KV EH T AIK+++R + K E + E+ +LR H + Sbjct: 80 YDIKALIGRGNFSKVVRVEHRVTKQPYAIKMIDRVQGK-----EVFESEVAVLRRVKHSY 134 Query: 301 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 480 II+L EV E +Y+VME GELFD I+ KG E++A R ++ GV+Y H + Sbjct: 135 IIQLIEVFETKDKVYMVMELATGGELFDRIIAKGSFTERDATRVLNMVLDGVKYLHGLGI 194 Query: 481 VHRDLKPENLLL---DNNCDVKIADFGLSNVMR 570 HRDLKPENLL ++ + I DFGLS+ + Sbjct: 195 THRDLKPENLLYYHPGHDSKIMITDFGLSSTRK 227
>KSG1_SCHPO (Q12701) Serine/threonine-protein kinase ksg1 (EC 2.7.11.1)| Length = 592 Score = 106 bits (264), Expect = 6e-23 Identities = 56/157 (35%), Positives = 88/157 (56%), Gaps = 1/157 (0%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 + +++ G+ LG GS+ V A T + AIK+L++R I E+ V E + L + Sbjct: 96 VSDFKFGEILGEGSYSTVLTATENSTKREYAIKVLDKRHIIKEKKEKYVNIEKEALCILS 155 Query: 292 -HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCH 468 HP I+L+ + ++Y V+ ++GEL DYI + GR E A+ + I+ + Y H Sbjct: 156 KHPGFIKLFYTFQDAHNLYFVLSLARNGELLDYINKLGRFNEICAQYYAALIVDSIDYMH 215 Query: 469 RNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGH 579 V+HRDLKPEN+LLD+N KI DFG + ++ H Sbjct: 216 GRGVIHRDLKPENILLDDNMRTKITDFGSAKILNSSH 252
>KPSH1_BRARE (Q501V0) Serine/threonine-protein kinase H1 homolog (EC 2.7.11.1)| Length = 422 Score = 105 bits (263), Expect = 7e-23 Identities = 60/155 (38%), Positives = 87/155 (56%), Gaps = 3/155 (1%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 Y I +G GSF +V EH T AIK++ R + ++ E E+ +LR H + Sbjct: 96 YDIKALIGRGSFSRVVRVEHRSTRQPYAIKMIETRYREGREVCES---ELCVLRRVRHTN 152 Query: 301 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 480 II+L EV E +Y+VME GELFD I+ +G E++A R Q ++ GV+Y H + Sbjct: 153 IIQLMEVFETAERVYMVMELATGGELFDRIITRGSFTERDATRVLQMVLDGVKYLHTLGI 212 Query: 481 VHRDLKPENLLLDN---NCDVKIADFGLSNVMRDG 576 HRDLKPENLL + + + I DFGL++ + G Sbjct: 213 THRDLKPENLLYYHPGADSKIMITDFGLASTRKKG 247
>TSSK6_MOUSE (Q925K9) Testis-specific serine/threonine-protein kinase 6 (EC| 2.7.11.1) (TSSK-6) (Small serine/threonine kinase) (Serine/threonine-protein kinase SSTK) Length = 273 Score = 105 bits (263), Expect = 7e-23 Identities = 60/146 (41%), Positives = 89/146 (60%), Gaps = 2/146 (1%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 Y++G+T+G GS+ KVK+A K VAIK+++RR+ + + + RE+ ILR HPH Sbjct: 12 YKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRELSILRGVRHPH 71 Query: 301 IIRLYEVIEA-PADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 477 I+ ++E IE +Y+VME + +L + GR+ +AR F QI V+Y H + Sbjct: 72 IVHVFEFIEVCNGKLYIVMEAAAT-DLLQAVQRNGRIPGSQARELFSQIAGAVRYLHDHH 130 Query: 478 VVHRDLKPENLLLD-NNCDVKIADFG 552 +VHRDLK EN+LL + VKI DFG Sbjct: 131 LVHRDLKCENVLLSPDERRVKITDFG 156
>CDPK2_MAIZE (P49101) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (CDPK 2)| Length = 513 Score = 105 bits (263), Expect = 7e-23 Identities = 59/156 (37%), Positives = 89/156 (57%), Gaps = 4/156 (2%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILR-LFMHP 297 Y GK LG G FG + I +G + A K +++RK+ + E ++REI+I++ L P Sbjct: 65 YSFGKELGRGQFGVTYLCTEIASGRQYACKSISKRKLVSKADREDIRREIQIMQHLSGQP 124 Query: 298 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 477 +I+ E ++++VVME GELFD I+ KG E+ A + +++ V CH Sbjct: 125 NIVEFRGAYEDKSNVHVVMELCAGGELFDRIIAKGHYTERAAATICRAVVNVVNICHFMG 184 Query: 478 VVHRDLKPENLLL---DNNCDVKIADFGLSNVMRDG 576 V+HRDLKPEN LL + N +K DFGLS + +G Sbjct: 185 VMHRDLKPENFLLATMEENAMLKATDFGLSVFIEEG 220
>KCC4_HUMAN (Q16566) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) Length = 473 Score = 105 bits (263), Expect = 7e-23 Identities = 62/152 (40%), Positives = 87/152 (57%), Gaps = 3/152 (1%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 + + LG G+ V + T A+K+L + K + V+ EI +L HP+ Sbjct: 46 FEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKKI-----VRTEIGVLLRLSHPN 100 Query: 301 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 480 II+L E+ E P +I +V+E V GELFD IVEKG E++A +QI+ V Y H N + Sbjct: 101 IIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHENGI 160 Query: 481 VHRDLKPENLLLDN---NCDVKIADFGLSNVM 567 VHRDLKPENLL + +KIADFGLS ++ Sbjct: 161 VHRDLKPENLLYATPAPDAPLKIADFGLSKIV 192
>PIM2_MOUSE (Q62070) Serine/threonine-protein kinase Pim-2 (EC 2.7.11.1)| Length = 370 Score = 105 bits (262), Expect = 1e-22 Identities = 62/171 (36%), Positives = 96/171 (56%), Gaps = 10/171 (5%) Frame = +1 Query: 91 GGKDGNPLK-NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMD-MEEKVKR 264 GGKD + YR+G LG G FG V + +VAIK+++R ++ + + V Sbjct: 80 GGKDRAAFEAEYRLGPLLGKGGFGTVFAGHRVTDRRQVAIKVISRNRVLGWSTVSDSVTC 139 Query: 265 EIKILRLFM------HPHIIRLYEVIEAPADIYVVMEY-VKSGELFDYIVEKGRLQEQEA 423 +++ L+ HP +IRL + E P +V+E + + +LFDYI EKG L E + Sbjct: 140 PLEVALLWKVGEGNGHPGVIRLLDWFETPEGFMLVLERPMPAQDLFDYITEKGPLGESCS 199 Query: 424 RRFFQQIISGVQYCHRNMVVHRDLKPENLLLD-NNCDVKIADFGLSNVMRD 573 R FF Q+++ VQ+CH VVHRD+K EN+L+D +K+ DFG ++ D Sbjct: 200 RSFFTQVVAAVQHCHARGVVHRDIKDENILIDLCRGSIKLIDFGSGALLHD 250
>CDPK_DAUCA (P28582) Calcium-dependent protein kinase (EC 2.7.11.1) (CDPK)| Length = 532 Score = 104 bits (260), Expect = 2e-22 Identities = 62/156 (39%), Positives = 89/156 (57%), Gaps = 4/156 (2%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILR-LFMHP 297 Y +GK LG G FG V +G A K + +RK+ + + +E +KREI+IL+ L P Sbjct: 81 YTLGKELGRGQFGCVYQCTENSSGQLYACKSILKRKLVSKNDKEDIKREIQILQHLSGQP 140 Query: 298 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 477 +I+ V E +++VME GELFD I+ +G E+ A +QI++ V CH Sbjct: 141 NIVEFKGVFEDRQSVHLVMELCAGGELFDRIIAQGHYSERAAATICRQIVNVVHVCHFMG 200 Query: 478 VVHRDLKPENLLL---DNNCDVKIADFGLSNVMRDG 576 V+HRDLKPEN LL D + +K DFGLS + +G Sbjct: 201 VMHRDLKPENFLLSSKDKDAMLKATDFGLSVFIEEG 236
>CDPK_SOYBN (P28583) Calcium-dependent protein kinase SK5 (EC 2.7.11.1) (CDPK)| Length = 508 Score = 104 bits (260), Expect = 2e-22 Identities = 60/156 (38%), Positives = 88/156 (56%), Gaps = 4/156 (2%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILR-LFMHP 297 Y +G+ LG G FG +G K A K + +RK+ + E V REI+I+ L H Sbjct: 34 YEVGRKLGQGQFGTTFECTRRASGGKFACKSIPKRKLLCKEDYEDVWREIQIMHHLSEHA 93 Query: 298 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 477 +++R+ E +++VME + GELFD IV+KG E++A R + I+ V+ CH Sbjct: 94 NVVRIEGTYEDSTAVHLVMELCEGGELFDRIVQKGHYSERQAARLIKTIVEVVEACHSLG 153 Query: 478 VVHRDLKPENLL---LDNNCDVKIADFGLSNVMRDG 576 V+HRDLKPEN L +D + +K DFGLS + G Sbjct: 154 VMHRDLKPENFLFDTIDEDAKLKATDFGLSVFYKPG 189
>YP150_YEAST (Q12152) Putative serine/threonine-protein kinase YPL150W (EC| 2.7.11.1) Length = 901 Score = 104 bits (259), Expect = 2e-22 Identities = 57/147 (38%), Positives = 82/147 (55%) Frame = +1 Query: 118 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 297 NY+I K +G GSFGKV +A H T KV +K ++ + + RE+ R F P Sbjct: 40 NYKILKQIGEGSFGKVYLALHRPTHRKVCLKTSDKN-------DPNIVREVFYHRQFDFP 92 Query: 298 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 477 +I +LYEVI + +++ +EY EL+D+++ R+ E F QI V Y H Sbjct: 93 YITKLYEVIVTESKVWMALEYCPGKELYDHLLSLRRISLLECGELFAQISGAVYYAHSMH 152 Query: 478 VVHRDLKPENLLLDNNCDVKIADFGLS 558 VHRDLK EN+LLD N + K+ DFG + Sbjct: 153 CVHRDLKLENILLDKNGNAKLTDFGFT 179
>KGS9_YEAST (P43637) Probable serine/threonine-protein kinase YGL179C (EC| 2.7.11.1) Length = 560 Score = 103 bits (258), Expect = 3e-22 Identities = 60/165 (36%), Positives = 96/165 (58%), Gaps = 16/165 (9%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNR-RKIKNMDMEEKVK-----REIK 273 L N+ I TLG G +GKVK+A + TG VAIKILNR K ++ KV+ +EI+ Sbjct: 47 LNNFEILATLGNGQYGKVKLARDLGTGALVAIKILNRFEKRSGYSLQLKVENPRVNQEIE 106 Query: 274 ILRLFMHPHIIRLYEVIEAPAD--IYVVMEYVKSG--------ELFDYIVEKGRLQEQEA 423 +++ H +++ LYE++ P +Y+V+EY G ++ V L Q++ Sbjct: 107 VMKRCHHENVVELYEILNDPESTKVYLVLEYCSRGPVKWCPENKMEIKAVGPSILTFQQS 166 Query: 424 RRFFQQIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLS 558 R+ ++SG++Y H + HRD+KP NLL+ +N VKI+DFG++ Sbjct: 167 RKVVLDVVSGLEYLHSQGITHRDIKPSNLLISSNGTVKISDFGVA 211
>CDPK2_ORYSA (P53683) Calcium-dependent protein kinase, isoform 2 (EC 2.7.11.1)| (CDPK 2) Length = 533 Score = 103 bits (258), Expect = 3e-22 Identities = 58/156 (37%), Positives = 90/156 (57%), Gaps = 4/156 (2%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILR-LFMHP 297 Y +GK LG G FG + I +G + A K +++RK+ + +E ++REI+I++ L Sbjct: 85 YSLGKELGRGQFGVTYLCTEIASGKQYACKSISKRKLVSKADKEDIRREIQIMQHLSGQQ 144 Query: 298 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 477 +I+ E ++++VVME GELFD I+ KG E+ A + +++ V CH Sbjct: 145 NIVEFRGAYEDKSNVHVVMELCAGGELFDRIIAKGHYSERAAATICRAVVNVVNICHFMG 204 Query: 478 VVHRDLKPENLLL---DNNCDVKIADFGLSNVMRDG 576 V+HRDLKPEN LL + N +K DFGLS + +G Sbjct: 205 VMHRDLKPENFLLATKEENAMLKATDFGLSVFIEEG 240
>PRKY_HUMAN (O43930) Serine/threonine-protein kinase PRKY (EC 2.7.11.1)| Length = 277 Score = 103 bits (257), Expect = 4e-22 Identities = 49/146 (33%), Positives = 81/146 (55%) Frame = +1 Query: 136 TLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPHIIRLY 315 T+G G+FG+V + + H A+K+++ + E+ V E +L+ HP +IRL+ Sbjct: 54 TMGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRRKQEQHVHNEKSVLKEVSHPFLIRLF 113 Query: 316 EVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMVVHRDL 495 +Y++MEYV GELF Y+ +G + +II ++Y H +V+RDL Sbjct: 114 WTWHEERFLYMLMEYVPGGELFSYLRNRGHFSSTTGLFYSAEIICAIEYLHSKEIVYRDL 173 Query: 496 KPENLLLDNNCDVKIADFGLSNVMRD 573 KPEN+LLD + +K+ DFG + + D Sbjct: 174 KPENILLDRDGHIKLTDFGFAKKLVD 199
>TSSK6_HUMAN (Q9BXA6) Testis-specific serine/threonine-protein kinase 6 (EC| 2.7.11.1) (TSSK-6) (Small serine/threonine kinase) (Serine/threonine-protein kinase SSTK) Length = 273 Score = 103 bits (256), Expect = 5e-22 Identities = 59/146 (40%), Positives = 89/146 (60%), Gaps = 2/146 (1%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 Y++G+T+G GS+ KVK+A K VAIK+++RR+ + + + RE+ ILR HPH Sbjct: 12 YKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRELSILRGVRHPH 71 Query: 301 IIRLYEVIEA-PADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNM 477 I+ ++E IE +Y+VME + +L + GR+ +AR F QI V+Y H + Sbjct: 72 IVHVFEFIEVCNGKLYIVMEAAAT-DLLQAVQRNGRIPGVQARDLFAQIAGAVRYLHDHH 130 Query: 478 VVHRDLKPENLLLD-NNCDVKIADFG 552 +VHRDLK EN+LL + VK+ DFG Sbjct: 131 LVHRDLKCENVLLSPDERRVKLTDFG 156
>CRK_DAUCA (P53681) CDPK-related protein kinase (EC 2.7.11.1) (PK421)| Length = 602 Score = 103 bits (256), Expect = 5e-22 Identities = 59/158 (37%), Positives = 93/158 (58%), Gaps = 8/158 (5%) Frame = +1 Query: 121 YRIGKTLGIGSFG---KVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILR-LF 288 + +G+ +G G FG + K + G VA+K++ + K+ E V+RE+KILR L Sbjct: 148 FEVGEEVGRGHFGYTCRAKFKKGEFKGQDVAVKVIPKAKMTTAIAIEDVRREVKILRALT 207 Query: 289 MHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKG-RLQEQEARRFFQQIISGVQYC 465 H ++++ Y+ E ++YVVME + GEL D I+ +G + E +A+ QI++ V +C Sbjct: 208 GHNNLVQFYDAFEDHTNVYVVMELCEGGELLDRILSRGGKYTEDDAKAVMIQILNVVAFC 267 Query: 466 HRNMVVHRDLKPENLLL---DNNCDVKIADFGLSNVMR 570 H VVHRDLKPEN L D + +K DFGLS+ ++ Sbjct: 268 HLQGVVHRDLKPENFLFKSKDEDSQLKAIDFGLSDYVK 305
>KAPB_SCHPO (P40376) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) Length = 512 Score = 103 bits (256), Expect = 5e-22 Identities = 55/154 (35%), Positives = 88/154 (57%) Frame = +1 Query: 97 KDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKI 276 KD ++++ +TLG GSFG+V + + AIK+L ++KI +M E E I Sbjct: 193 KDRYGIQDFNFLQTLGTGSFGRVHLVQSNHNRLYYAIKVLEKKKIVDMKQIEHTCDERYI 252 Query: 277 LRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGV 456 L HP I L+ + ++++VM++ + GELF + + R E+ A+ + ++I + Sbjct: 253 LSRVQHPFITILWGTFQDAKNLFMVMDFAEGGELFSLLRKCHRFPEKVAKFYAAEVILAL 312 Query: 457 QYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLS 558 Y H N +V+RDLKPENLLLD +KI DFG + Sbjct: 313 DYLHHNQIVYRDLKPENLLLDRFGHLKIVDFGFA 346
>FUSED_DROME (P23647) Serine/threonine-protein kinase fused (EC 2.7.11.1)| Length = 805 Score = 103 bits (256), Expect = 5e-22 Identities = 55/155 (35%), Positives = 86/155 (55%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 + Y + +G GSFG V A VAIK++++R +++ ++RE I Sbjct: 1 MNRYAVSSLVGQGSFGCVYKATRKDDSKVVAIKVISKRGRATKELKN-LRRECDIQARLK 59 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 HPH+I + E E+ D++VV E+ +L Y+ G + E+ ARR ++S + Y H Sbjct: 60 HPHVIEMIESFESKTDLFVVTEFALM-DLHRYLSYNGAMGEEPARRVTGHLVSALYYLHS 118 Query: 472 NMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDG 576 N ++HRDLKP+N+LLD N K+ DFGL+ M G Sbjct: 119 NRILHRDLKPQNVLLDKNMHAKLCDFGLARNMTLG 153
>ZYG1_CAEBR (Q621J7) Probable serine/threonine-protein kinase zyg-1 (EC| 2.7.11.1) (Zygote defective protein 1) Length = 709 Score = 102 bits (255), Expect = 6e-22 Identities = 57/161 (35%), Positives = 90/161 (55%), Gaps = 4/161 (2%) Frame = +1 Query: 88 AGGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKRE 267 +GGK G L +++ + +G G FG V A+ + G KVAIK KI N + ++K E Sbjct: 2 SGGKSGTKLSSFQNLQQIGQGGFGVVYSAQR-ENGEKVAIK-----KIGNAASQTRIKEE 55 Query: 268 IKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQII 447 IK ++L H +I++ YE + Y+VME + G L DY+ +KG L + A +Q+I Sbjct: 56 IKTMKLLRHRNIVQFYETFFENGETYLVMELCEGGSLMDYVKQKGPLDDSTAVHILRQLI 115 Query: 448 SGVQYCHRNMVVHRDLKPENLLL----DNNCDVKIADFGLS 558 + V+Y H ++HRDL N+ + + VK+ DFGL+ Sbjct: 116 AAVKYIHDENILHRDLSAGNVFIKDATKSTITVKLGDFGLA 156
>IPL1_CANAL (Q59S66) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 530 Score = 102 bits (254), Expect = 8e-22 Identities = 49/149 (32%), Positives = 89/149 (59%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 L ++ GK LG G G+V +H ++G A+K++++ +I N+ +E+ ++REI+I Sbjct: 241 LDDFEFGKILGKGKLGRVYCVKHKQSGLIFALKVMSKSEIMNLKLEKSLRREIEIQSNLY 300 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 H +I RLY +IY+++EY GEL+ ++ + R A + QI + + H+ Sbjct: 301 HINITRLYSWFHDSINIYLLLEYSIEGELYTHLKKLKRFDNIMASNYIFQITQALIFLHQ 360 Query: 472 NMVVHRDLKPENLLLDNNCDVKIADFGLS 558 ++HRDLKPEN+++ + +K++DFG S Sbjct: 361 RGIIHRDLKPENIMISLDNQLKLSDFGWS 389
>CDPK1_ORYSA (P53682) Calcium-dependent protein kinase, isoform 1 (EC 2.7.11.1)| (CDPK 1) Length = 534 Score = 102 bits (253), Expect = 1e-21 Identities = 60/166 (36%), Positives = 91/166 (54%), Gaps = 4/166 (2%) Frame = +1 Query: 91 GGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREI 270 G K N + Y +G+ LG G FGK + I TG + A K + + ++ + E V+REI Sbjct: 63 GYKTPNVRELYTLGRELGQGQFGKTYLCTEISTGCQYACKTILKSNLRCVSDIEDVRREI 122 Query: 271 KILR-LFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQII 447 +I+ L +I+ + + E +++VME GELF I ++G E++A + I+ Sbjct: 123 QIMHHLSGQKNIVTIKDTYEDEQAVHIVMELCAGGELFSKIQKRGHYSERKAAELIKIIV 182 Query: 448 SGVQYCHRNMVVHRDLKPENLLL---DNNCDVKIADFGLSNVMRDG 576 ++ CH + V+HRDLKPEN LL D+ VK DFGLS R G Sbjct: 183 GIIETCHSHGVMHRDLKPENFLLLDADDEFSVKAIDFGLSVFFRPG 228
>M3K2_HUMAN (Q9Y2U5) Mitogen-activated protein kinase kinase kinase 2 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2) Length = 619 Score = 102 bits (253), Expect = 1e-21 Identities = 53/151 (35%), Positives = 89/151 (58%), Gaps = 4/151 (2%) Frame = +1 Query: 118 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEE--KVKREIKILRLFM 291 N+R+GK LG G+FG+V + + TG ++A+K + +E ++ EI++L+ + Sbjct: 355 NWRLGKLLGQGAFGRVYLCYDVDTGRELAVKQVQFDPDSPETSKEVNALECEIQLLKNLL 414 Query: 292 HPHIIRLYEVIEAPAD--IYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYC 465 H I++ Y + P + + + MEY+ G + D + G L E R++ +QI+ GV Y Sbjct: 415 HERIVQYYGCLRDPQEKTLSIFMEYMPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYL 474 Query: 466 HRNMVVHRDLKPENLLLDNNCDVKIADFGLS 558 H NM+VHRD+K N+L D+ +VK+ DFG S Sbjct: 475 HSNMIVHRDIKGANILRDSTGNVKLGDFGAS 505
>KPC4_DROME (P83099) Putative protein kinase C, delta type homolog (EC| 2.7.11.13) Length = 643 Score = 101 bits (252), Expect = 1e-21 Identities = 58/153 (37%), Positives = 89/153 (58%), Gaps = 6/153 (3%) Frame = +1 Query: 115 KNYRIGK-----TLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKIL 279 KNY + LG GSFGKV +AE T + AIK L + + D + E K+L Sbjct: 308 KNYSVDDFHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDVDSTLIERKVL 367 Query: 280 RL-FMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGV 456 L HP++ L+ + + ++ VMEY+ G+L +I E GR E+ AR + +IISG+ Sbjct: 368 ALGTKHPYLCHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGRFSEERARFYGAEIISGL 427 Query: 457 QYCHRNMVVHRDLKPENLLLDNNCDVKIADFGL 555 ++ H+ +++RDLK +N+LLD V+IADFG+ Sbjct: 428 KFLHKKGIIYRDLKLDNVLLDYEGHVRIADFGM 460
>MASTL_MOUSE (Q8C0P0) Microtubule-associated serine/threonine-protein| kinase-like (EC 2.7.11.1) Length = 865 Score = 101 bits (252), Expect = 1e-21 Identities = 48/151 (31%), Positives = 90/151 (59%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 ++ + I K + G+FGKV + + K G A+K++ + + N +M +V+ E L L Sbjct: 31 IEEFTIVKPISRGAFGKVYLGQ--KGGKLYAVKVVKKADMVNKNMTHQVQAERDALALSK 88 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 P ++ LY +++ ++IY++MEY+ G++ + G E+ A ++ ++ + Y HR Sbjct: 89 SPFVVHLYYSLQSASNIYLIMEYLIGGDVKSLLHIYGYFDEEMAIKYISEVALALDYLHR 148 Query: 472 NMVVHRDLKPENLLLDNNCDVKIADFGLSNV 564 + ++HRDLKP+N+L+ N +K+ DFGLS V Sbjct: 149 HGIIHRDLKPDNMLISNEGHIKLTDFGLSKV 179
>PRKX_MOUSE (Q922R0) Serine/threonine-protein kinase PRKX (EC 2.7.11.1)| (PKA-related protein kinase) Length = 355 Score = 101 bits (252), Expect = 1e-21 Identities = 53/160 (33%), Positives = 93/160 (58%), Gaps = 1/160 (0%) Frame = +1 Query: 97 KDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKV-AIKILNRRKIKNMDMEEKVKREIK 273 K G+ L+++ T+G G+FG+V + + KTG + A+KI++ + + E+ V+ E Sbjct: 38 KAGHSLQDWDTIATVGTGTFGRVNLVKE-KTGRQYCALKIMSIPDVIRLKQEQHVQNEKA 96 Query: 274 ILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISG 453 +L+ HP +I+L +Y++ME+V GELF Y+ +GR + + +I+ Sbjct: 97 VLKEINHPFLIKLLWTGHDNRFLYMLMEFVPGGELFTYLRNRGRFSSVASVFYATEIVCA 156 Query: 454 VQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRD 573 ++Y H +V+RDLKPEN+LLD +K+ DFG + + D Sbjct: 157 IEYLHSKEIVYRDLKPENILLDREGHIKLTDFGFAKKLVD 196
>KOK0_YEAST (Q12236) Probable serine/threonine-protein kinase YOL100W (EC| 2.7.11.1) Length = 1081 Score = 101 bits (251), Expect = 2e-21 Identities = 48/158 (30%), Positives = 89/158 (56%), Gaps = 6/158 (3%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNR------RKIKNMDMEEKVKREIK 273 +K+++ G +G G++ V +A I T + A K+LN+ +K+K + +E+ Sbjct: 176 IKDFKFGSVIGDGAYSTVMLATSIDTKKRYAAKVLNKEYLIRQKKVKYVSIEKTA----- 230 Query: 274 ILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISG 453 + +L P ++RL+ + + +Y ++EY +G+ + + G L E AR + QII Sbjct: 231 LQKLNNSPSVVRLFSTFQDESSLYFLLEYAPNGDFLSLMKKYGSLDETCARYYAAQIIDA 290 Query: 454 VQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVM 567 + Y H N ++HRD+KPEN+LLD +K+ DFG + ++ Sbjct: 291 IDYLHSNGIIHRDIKPENILLDGEMKIKLTDFGTAKLL 328
>STK11_HUMAN (Q15831) Serine/threonine-protein kinase 11 (EC 2.7.11.1)| (Serine/threonine-protein kinase LKB1) (NY-REN-19 antigen) Length = 433 Score = 100 bits (250), Expect = 2e-21 Identities = 59/154 (38%), Positives = 95/154 (61%), Gaps = 5/154 (3%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNM-DMEEKVKREIKILRLFMHP 297 Y +G LG GS+GKVK +T + A+KIL ++K++ + + E VK+EI++LR H Sbjct: 49 YLMGDLLGEGSYGKVKEVLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHK 108 Query: 298 HIIRLYEVI--EAPADIYVVMEYVKSG--ELFDYIVEKGRLQEQEARRFFQQIISGVQYC 465 ++I+L +V+ E +Y+VMEY G E+ D + EK R +A +F Q+I G++Y Sbjct: 109 NVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDSVPEK-RFPVCQAHGYFCQLIDGLEYL 167 Query: 466 HRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVM 567 H +VH+D+KP NLLL +KI+D G++ + Sbjct: 168 HSQGIVHKDIKPGNLLLTTGGTLKISDLGVAEAL 201
>KS6A5_CHICK (Q5F3L1) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1)| Length = 789 Score = 100 bits (250), Expect = 2e-21 Identities = 61/163 (37%), Positives = 92/163 (56%), Gaps = 7/163 (4%) Frame = +1 Query: 97 KDGNPLKNYRIG---KTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKRE 267 KD ++Y + K LG GSF + H KT + A+KI+++R ME +RE Sbjct: 405 KDSPFFQHYELDLKEKPLGEGSFSICRKCLHKKTSQEYAVKIISKR------MEANTQRE 458 Query: 268 IKILRLFM-HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQI 444 I L+L HP++++L+EV ++VME +K GEL + I +K E EA +++ Sbjct: 459 ITALKLCEGHPNVVKLHEVYHDQLHTFLVMELLKGGELLERIQKKQHFSETEASHIMRRL 518 Query: 445 ISGVQYCHRNMVVHRDLKPENLLL---DNNCDVKIADFGLSNV 564 +S V + H VVHRDLKPENLL +N ++KI DFG + + Sbjct: 519 VSAVSHMHDVGVVHRDLKPENLLFTDETDNSEIKIIDFGFARL 561 Score = 86.3 bits (212), Expect = 6e-17 Identities = 42/154 (27%), Positives = 89/154 (57%), Gaps = 5/154 (3%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIK---TGHKVAIKILNRRKI-KNMDMEEKVKREIKIL 279 ++N+ + K LG G++GKV + + G A+K+L + I + E + E ++L Sbjct: 36 IENFELLKVLGTGAYGKVFLVRKVSGHDAGKLYAMKVLKKATIVQKAKTTEHTRTERQVL 95 Query: 280 R-LFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGV 456 + P ++ L+ + ++++++Y+ GELF ++ ++ R E E + + +I+ + Sbjct: 96 EHIRQSPFLVTLHYAFQTDTKLHLILDYINGGELFTHLSQRERFSENEVQIYIGEIVLAL 155 Query: 457 QYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLS 558 ++ H+ +++RD+K EN+LLD++ V + DFGLS Sbjct: 156 EHLHKLGIIYRDIKLENILLDSDGHVVLTDFGLS 189
>RIM15_YEAST (P43565) Serine/threonine-protein kinase RIM15 (EC 2.7.11.1)| Length = 1770 Score = 100 bits (249), Expect = 3e-21 Identities = 55/150 (36%), Positives = 88/150 (58%), Gaps = 1/150 (0%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 +K+Y I K + G++G V +A TG AIK+L + + + VK E I+ + Sbjct: 791 IKDYDILKPISKGAYGSVYLARKKLTGDYFAIKVLRKSDMIAKNQVTNVKSERAIMMVQS 850 Query: 292 H-PHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCH 468 P++ RL+ + ++++VMEY+ G+L I G L +Q A+++ +I+ GV H Sbjct: 851 DKPYVARLFASFQNKDNLFLVMEYLPGGDLATLIKMMGYLPDQWAKQYLTEIVVGVNDMH 910 Query: 469 RNMVVHRDLKPENLLLDNNCDVKIADFGLS 558 +N ++H DLKPENLL+DN VK+ DFGLS Sbjct: 911 QNGIIHHDLKPENLLIDNAGHVKLTDFGLS 940
>MASTL_HUMAN (Q96GX5) Microtubule-associated serine/threonine-protein| kinase-like (EC 2.7.11.1) Length = 879 Score = 100 bits (249), Expect = 3e-21 Identities = 49/151 (32%), Positives = 89/151 (58%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 ++ + I K + G+FGKV + + K G A+K++ + + N +M +V+ E L L Sbjct: 32 IEEFSIVKPISRGAFGKVYLGQ--KGGKLYAVKVVKKADMINKNMTHQVQAERDALALSK 89 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 P I+ LY +++ ++Y+VMEY+ G++ + G E+ A ++ ++ + Y HR Sbjct: 90 SPFIVHLYYSLQSANNVYLVMEYLIGGDVKSLLHIYGYFDEEMAVKYISEVALALDYLHR 149 Query: 472 NMVVHRDLKPENLLLDNNCDVKIADFGLSNV 564 + ++HRDLKP+N+L+ N +K+ DFGLS V Sbjct: 150 HGIIHRDLKPDNMLISNEGHIKLTDFGLSKV 180
>PKD1_DICDI (P34100) Developmentally-regulated protein kinase 1 (EC 2.7.11.1)| (Fragment) Length = 416 Score = 100 bits (249), Expect = 3e-21 Identities = 48/149 (32%), Positives = 77/149 (51%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFM 291 + ++ +LG GSFG K+ H +G K L R I + +E V EI I+ Sbjct: 33 ISDFNFYGSLGSGSFGTAKLCRHRGSGLFFCSKTLRRETIVHEKHKEHVNNEINIMLNIS 92 Query: 292 HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHR 471 HP+I++ Y P I+ +MEY +LF ++ EQ + +I+ ++Y H Sbjct: 93 HPYIVKTYSTFNTPTKIHFIMEYAGKKDLFHHLRANKCFTEQTTKLIVAEIVLAIEYLHA 152 Query: 472 NMVVHRDLKPENLLLDNNCDVKIADFGLS 558 +++RDLKPEN+L+D +K+ DFG S Sbjct: 153 ENIIYRDLKPENILIDEKGHIKLTDFGFS 181
>CDPK2_PLAF7 (Q8ICR0) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (PfCDPK2)| Length = 508 Score = 100 bits (249), Expect = 3e-21 Identities = 62/157 (39%), Positives = 88/157 (56%), Gaps = 3/157 (1%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 Y I + LG G++G V T AIK + ++KN++ + +EI+I++ HP+ Sbjct: 71 YIIDEKLGQGTYGCVYKGIDKVTNQLYAIKEEKKDRLKNIN---RFFQEIEIMKKLDHPN 127 Query: 301 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 480 I++LYE E IY++ME ELFD I+E G E+ A +QI S + Y H + Sbjct: 128 IVKLYETYENDNYIYLIMELCSGRELFDSIIENGSFTEKNAATIMKQIFSAIFYLHSLNI 187 Query: 481 VHRDLKPENLLLDN-NCD--VKIADFGLSNVMRDGHF 582 VHRDLKPEN L + N D +KI DFGLS + G F Sbjct: 188 VHRDLKPENFLFQSENKDSLLKIIDFGLSKNLGTGEF 224
>KKCC2_HUMAN (Q96RR4) Calcium/calmodulin-dependent protein kinase kinase 2 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta) Length = 588 Score = 100 bits (249), Expect = 3e-21 Identities = 60/182 (32%), Positives = 98/182 (53%), Gaps = 25/182 (13%) Frame = +1 Query: 91 GGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRK-------------- 228 G +D L Y + +G GS+G VK+A + A+K+L+++K Sbjct: 155 GMQDCVQLNQYTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPR 214 Query: 229 ---------IKNMDMEEKVKREIKILRLFMHPHIIRLYEVIEAPAD--IYVVMEYVKSGE 375 I+ E+V +EI IL+ HP++++L EV++ P + +Y+V E V G Sbjct: 215 GTRPAPGGCIQPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGP 274 Query: 376 LFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGL 555 + + K L E +AR +FQ +I G++Y H ++HRD+KP NLL+ + +KIADFG+ Sbjct: 275 VMEVPTLKP-LSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGV 333 Query: 556 SN 561 SN Sbjct: 334 SN 335
>CDPK2_PLAFK (O15865) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (PfCDPK2)| Length = 512 Score = 100 bits (249), Expect = 3e-21 Identities = 62/157 (39%), Positives = 88/157 (56%), Gaps = 3/157 (1%) Frame = +1 Query: 121 YRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPH 300 Y I + LG G++G V T AIK + ++KN++ + +EI+I++ HP+ Sbjct: 71 YIIDEKLGQGTYGCVYKGIDKVTNQLYAIKEEKKDRLKNIN---RFFQEIEIMKKLDHPN 127 Query: 301 IIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMV 480 I++LYE E IY++ME ELFD I+E G E+ A +QI S + Y H + Sbjct: 128 IVKLYETYENDNYIYLIMELCSGRELFDSIIENGSFTEKNAATIMKQIFSAIFYLHSLNI 187 Query: 481 VHRDLKPENLLLDN-NCD--VKIADFGLSNVMRDGHF 582 VHRDLKPEN L + N D +KI DFGLS + G F Sbjct: 188 VHRDLKPENFLFQSENKDSLLKIIDFGLSKNLGTGEF 224
>KKCC2_RAT (O88831) Calcium/calmodulin-dependent protein kinase kinase 2 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta) Length = 587 Score = 100 bits (248), Expect = 4e-21 Identities = 60/182 (32%), Positives = 98/182 (53%), Gaps = 25/182 (13%) Frame = +1 Query: 91 GGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRK-------------- 228 G +D L Y + +G GS+G VK+A + A+K+L+++K Sbjct: 154 GLQDCVQLNQYTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPR 213 Query: 229 ---------IKNMDMEEKVKREIKILRLFMHPHIIRLYEVIEAPAD--IYVVMEYVKSGE 375 I+ E+V +EI IL+ HP++++L EV++ P + +Y+V E V G Sbjct: 214 GTRPAPGGCIQPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGP 273 Query: 376 LFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGL 555 + + K L E +AR +FQ +I G++Y H ++HRD+KP NLL+ + +KIADFG+ Sbjct: 274 VMEVPTLKP-LSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGV 332 Query: 556 SN 561 SN Sbjct: 333 SN 334
>KKCC2_MOUSE (Q8C078) Calcium/calmodulin-dependent protein kinase kinase 2 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta) Length = 588 Score = 100 bits (248), Expect = 4e-21 Identities = 60/182 (32%), Positives = 98/182 (53%), Gaps = 25/182 (13%) Frame = +1 Query: 91 GGKDGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRK-------------- 228 G +D L Y + +G GS+G VK+A + A+K+L+++K Sbjct: 155 GLQDCVQLNQYTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPR 214 Query: 229 ---------IKNMDMEEKVKREIKILRLFMHPHIIRLYEVIEAPAD--IYVVMEYVKSGE 375 I+ E+V +EI IL+ HP++++L EV++ P + +Y+V E V G Sbjct: 215 GARPAPGGCIQPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGP 274 Query: 376 LFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGL 555 + + K L E +AR +FQ +I G++Y H ++HRD+KP NLL+ + +KIADFG+ Sbjct: 275 VMEVPTLKP-LSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGV 333 Query: 556 SN 561 SN Sbjct: 334 SN 335
>ULK2_HUMAN (Q8IYT8) Serine/threonine-protein kinase ULK2 (EC 2.7.11.1)| (Unc-51-like kinase 2) Length = 1036 Score = 99.8 bits (247), Expect = 5e-21 Identities = 56/153 (36%), Positives = 86/153 (56%), Gaps = 10/153 (6%) Frame = +1 Query: 139 LGIGSFGKVKIAEHI-KTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPHIIRLY 315 +G G+F V H KT +VAIK +N++ + + + +EIKIL+ H +I+ LY Sbjct: 15 VGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQI--LLGKEIKILKELQHENIVALY 72 Query: 316 EVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMVVHRDL 495 +V E P +++VMEY G+L DY+ KG L E R F QI + ++ H ++HRDL Sbjct: 73 DVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMRILHSKGIIHRDL 132 Query: 496 KPENLLLD---------NNCDVKIADFGLSNVM 567 KP+N+LL + +KIADFG + + Sbjct: 133 KPQNILLSYANRRKSSVSGIRIKIADFGFARYL 165
>PHKG1_HUMAN (Q16816) Phosphorylase b kinase gamma catalytic chain, skeletal| muscle isoform (EC 2.7.11.19) (Phosphorylase kinase gamma subunit 1) Length = 386 Score = 99.8 bits (247), Expect = 5e-21 Identities = 56/164 (34%), Positives = 91/164 (55%), Gaps = 7/164 (4%) Frame = +1 Query: 115 KNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNM------DMEEKVKREIKI 276 +NY + LG G V+ H T + A+K+++ + ++ E +E+ I Sbjct: 17 ENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEVDI 76 Query: 277 LRLFM-HPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISG 453 LR HP+II+L + E ++V + +K GELFDY+ EK L E+E R+ + ++ Sbjct: 77 LRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALLEV 136 Query: 454 VQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFL 585 + H+ +VHRDLKPEN+LLD+N ++K+ DFG S + G L Sbjct: 137 ICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGERL 180
>ULK2_MOUSE (Q9QY01) Serine/threonine-protein kinase ULK2 (EC 2.7.11.1)| (Unc-51-like kinase 2) (Serine/threonine-protein kinase Unc51.2) Length = 1037 Score = 99.8 bits (247), Expect = 5e-21 Identities = 56/153 (36%), Positives = 86/153 (56%), Gaps = 10/153 (6%) Frame = +1 Query: 139 LGIGSFGKVKIAEHI-KTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHPHIIRLY 315 +G G+F V H KT +VAIK +N++ + + + +EIKIL+ H +I+ LY Sbjct: 15 VGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQI--LLGKEIKILKELQHENIVALY 72 Query: 316 EVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYCHRNMVVHRDL 495 +V E P +++VMEY G+L DY+ KG L E R F QI + ++ H ++HRDL Sbjct: 73 DVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMRILHSKGIIHRDL 132 Query: 496 KPENLLLD---------NNCDVKIADFGLSNVM 567 KP+N+LL + +KIADFG + + Sbjct: 133 KPQNILLSYANRRKSNVSGIRIKIADFGFARYL 165
>PHKG1_RAT (P13286) Phosphorylase b kinase gamma catalytic chain, skeletal| muscle isoform (EC 2.7.11.19) (Phosphorylase kinase gamma subunit 1) Length = 387 Score = 99.4 bits (246), Expect = 7e-21 Identities = 58/167 (34%), Positives = 94/167 (56%), Gaps = 7/167 (4%) Frame = +1 Query: 106 NPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRR------KIKNMDMEEKVKRE 267 N +NY + LG G V+ H T + A+KI++ + ++ E +E Sbjct: 14 NFYENYEPKEILGRGVSSVVRRCIHKPTCQEYAVKIIDITGGGSFSSEEVQELREATLKE 73 Query: 268 IKIL-RLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQI 444 + IL ++ HP+II+L + E ++V + +K GELFDY+ EK L E+E R+ + + Sbjct: 74 VDILQKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLTEKETRKIMRAL 133 Query: 445 ISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLSNVMRDGHFL 585 + V H+ +VHRDLKPEN+LLD+N ++K+ DFG S ++ G L Sbjct: 134 LEVVCTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLQPGEKL 180
>PAK1_YEAST (P38990) Serine/threonine-protein kinase PAK1 (EC 2.7.11.1)| Length = 1142 Score = 99.4 bits (246), Expect = 7e-21 Identities = 61/170 (35%), Positives = 93/170 (54%), Gaps = 21/170 (12%) Frame = +1 Query: 112 LKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKN-----------MDMEEKV 258 L Y I K LG G GKVK+A I + VAIKI++R + K + +K+ Sbjct: 130 LNTYEIIKELGHGQHGKVKLARDILSKQLVAIKIVDRHEKKQRKFFTFIKSSKISENDKI 189 Query: 259 KREIKILRLFMHPHIIRLYEVIE--APADIYVVMEYVKSGELF----DYIVEKGR----L 408 KREI I++ H H+++L EV++ IY+V+EY GE+ D + + L Sbjct: 190 KREIAIMKKCHHKHVVQLIEVLDDLKSRKIYLVLEYCSRGEVKWCPPDCMESDAKGPSLL 249 Query: 409 QEQEARRFFQQIISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLS 558 QE R + ++ G++Y H ++HRD+KP NLL+ + VKI+DFG+S Sbjct: 250 SFQETREILRGVVLGLEYLHYQGIIHRDIKPANLLISGDGTVKISDFGVS 299
>M3K2_MOUSE (Q61083) Mitogen-activated protein kinase kinase kinase 2 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2) Length = 619 Score = 99.4 bits (246), Expect = 7e-21 Identities = 51/151 (33%), Positives = 87/151 (57%), Gaps = 4/151 (2%) Frame = +1 Query: 118 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKIL--NRRKIKNMDMEEKVKREIKILRLFM 291 N+R+GK LG G+FG+V + + TG ++A+K + N + ++ EI++L+ + Sbjct: 355 NWRLGKLLGQGAFGRVYLCYDVDTGRELAVKQVQFNPESPETSKEVNALECEIQLLKNLL 414 Query: 292 HPHIIRLYEVIEAPAD--IYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQYC 465 H I++ Y + P + + + ME G + D + G L E R++ +QI+ GV Y Sbjct: 415 HERIVQYYGCLRDPQEKTLSIFMELSPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYL 474 Query: 466 HRNMVVHRDLKPENLLLDNNCDVKIADFGLS 558 H NM+VHRD+K N+L D+ ++K+ DFG S Sbjct: 475 HSNMIVHRDIKGANILRDSTGNIKLGDFGAS 505
>KS6A_CAEEL (Q21734) Putative ribosomal protein S6 kinase alpha (EC 2.7.11.1)| Length = 784 Score = 99.4 bits (246), Expect = 7e-21 Identities = 49/158 (31%), Positives = 94/158 (59%), Gaps = 3/158 (1%) Frame = +1 Query: 94 GKDGNPLKNYRIGKTLGIGSFGKVKIAEHIK---TGHKVAIKILNRRKIKNMDMEEKVKR 264 G+ +P + + + K LG GSFGKV + ++ +GH A+K+L + +K D ++ K Sbjct: 96 GEKADP-RQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLKVRD-RQRTKL 153 Query: 265 EIKILRLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQI 444 E IL HP I++L+ + +Y+++++++ G+LF + ++ E + + + ++ Sbjct: 154 ERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYLAEL 213 Query: 445 ISGVQYCHRNMVVHRDLKPENLLLDNNCDVKIADFGLS 558 +++ H +V+RDLKPEN+LLD + +K+ DFGLS Sbjct: 214 TLALEHLHSLGIVYRDLKPENILLDADGHIKVTDFGLS 251 Score = 68.2 bits (165), Expect = 2e-11 Identities = 47/156 (30%), Positives = 75/156 (48%), Gaps = 5/156 (3%) Frame = +1 Query: 118 NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKILRLFMHP 297 +Y I + +G G+ V + T K A+KI+ + D E+V +LR H Sbjct: 453 DYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVF---DATEEVDI---LLRHSHHQ 506 Query: 298 HIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRL-QEQEARRFFQQIISGVQYCHRN 474 +++L++V E IY++ E + GEL D +V K L E+E +++ VQY H Sbjct: 507 FVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLNAVQYLHSQ 566 Query: 475 MVVHRDLKPENLLL----DNNCDVKIADFGLSNVMR 570 V HRDL N+L + ++I DFG + R Sbjct: 567 QVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSR 602
>PIM2_HUMAN (Q9P1W9) Serine/threonine-protein kinase Pim-2 (EC 2.7.11.1)| (Pim-2h) Length = 311 Score = 99.4 bits (246), Expect = 7e-21 Identities = 61/172 (35%), Positives = 94/172 (54%), Gaps = 11/172 (6%) Frame = +1 Query: 91 GGKDGNPLK-NYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMD-MEEKVKR 264 GGKD + YR+G LG G FG V + +VAIK++ R ++ + + V Sbjct: 21 GGKDREAFEAEYRLGPLLGKGGFGTVFAGHRLTDRLQVAIKVIPRNRVLGWSPLSDSVTC 80 Query: 265 EIKILRLFM------HPHIIRLYEVIEAPADIYVVMEY-VKSGELFDYIVEKGRLQEQEA 423 +++ L+ HP +IRL + E +V+E + + +LFDYI EKG L E + Sbjct: 81 PLEVALLWKVGAGGGHPGVIRLLDWFETQEGFMLVLERPLPAQDLFDYITEKGPLGEGPS 140 Query: 424 RRFFQQIISGVQYCHRNMVVHRDLKPENLLLD--NNCDVKIADFGLSNVMRD 573 R FF Q+++ +Q+CH VVHRD+K EN+L+D C K+ DFG ++ D Sbjct: 141 RCFFGQVVAAIQHCHSRGVVHRDIKDENILIDLRRGC-AKLIDFGSGALLHD 191
>KPSH2_HUMAN (Q96QS6) Serine/threonine-protein kinase H2 (EC 2.7.11.1) (PSK-H2)| Length = 385 Score = 99.4 bits (246), Expect = 7e-21 Identities = 55/156 (35%), Positives = 81/156 (51%), Gaps = 3/156 (1%) Frame = +1 Query: 100 DGNPLKNYRIGKTLGIGSFGKVKIAEHIKTGHKVAIKILNRRKIKNMDMEEKVKREIKIL 279 D L Y I +G GSF +V E T AIK++ R+ + E E+ +L Sbjct: 56 DPRVLARYDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREG---REACVSELSVL 112 Query: 280 RLFMHPHIIRLYEVIEAPADIYVVMEYVKSGELFDYIVEKGRLQEQEARRFFQQIISGVQ 459 R H +I++L E+ E +Y+VME GELFD ++ +G E++A R Q + G++ Sbjct: 113 RRVSHRYIVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIR 172 Query: 460 YCHRNMVVHRDLKPENLLL---DNNCDVKIADFGLS 558 Y H + HR+LKPENLL + I DFGL+ Sbjct: 173 YLHALQITHRNLKPENLLYYHPGEESKILITDFGLA 208 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 79,577,754 Number of Sequences: 219361 Number of extensions: 1677115 Number of successful extensions: 8930 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 7043 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 7367 length of database: 80,573,946 effective HSP length: 106 effective length of database: 57,321,680 effective search space used: 5101629520 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
