ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | baal41k15 |
|---|---|
| Clone Library Name | barley_pub |
>DHGY_CUCSA (P13443) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-dependent| hydroxypyruvate reductase) (HPR) (GDH) Length = 382 Score = 323 bits (827), Expect = 3e-88 Identities = 157/194 (80%), Positives = 172/194 (88%) Frame = +1 Query: 1 MAVGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDG 180 MAVGY NVDV+AANK G+A+GNTPGVLTETT RRIVEAD+FMRAG YDG Sbjct: 93 MAVGYNNVDVNAANKYGVAVGNTPGVLTETTAELAASLSLAAARRIVEADEFMRAGRYDG 152 Query: 181 WLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQ 360 WLP+LFVGNLLKGQTVGVIGAGRIGSAYARMM+EGFKMNLIYFDLYQSTRLEKFVTAYG+ Sbjct: 153 WLPNLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGE 212 Query: 361 FLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNAS 540 FLKANGE PVTW+RASSM+EVLREADVISLHPVLDKTT+HL+N E L MKK+A+L+N S Sbjct: 213 FLKANGEAPVTWRRASSMDEVLREADVISLHPVLDKTTFHLVNKESLKAMKKDAILINCS 272 Query: 541 RGPVIDEVALVEHL 582 RGPVIDE ALV+HL Sbjct: 273 RGPVIDEAALVDHL 286
>GYAR_THELI (Q9C4M5) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 331 Score = 141 bits (356), Expect = 1e-33 Identities = 82/198 (41%), Positives = 114/198 (57%), Gaps = 5/198 (2%) Frame = +1 Query: 4 AVGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYD-- 177 AVGY N+D++ A K GI + NTPGVLT+ T RRIVEAD F+R+G + Sbjct: 75 AVGYDNIDIEEATKRGIYVTNTPGVLTDATADLAFALLLAVARRIVEADAFVRSGEWKKS 134 Query: 178 --GWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTA 351 GW P +F+G LKG+T+G++G GRIG A A+ +GF M +IY+ + E+ + A Sbjct: 135 EVGWHPLMFLGYGLKGKTLGIVGFGRIGQALAK-RAKGFGMKIIYYSRTRKPEAEEEIGA 193 Query: 352 -YGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVL 528 Y F E +L+E+D ISLH L K TYH+I + L +MK A+L Sbjct: 194 EYVDF-----------------ETLLKESDFISLHVPLTKETYHMIGEKELKLMKPNAIL 236 Query: 529 VNASRGPVIDEVALVEHL 582 +N SRG V+D AL++ L Sbjct: 237 INTSRGAVVDTNALIKAL 254
>GYAR_PYRAB (Q9UYR1) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 335 Score = 137 bits (344), Expect = 3e-32 Identities = 77/197 (39%), Positives = 111/197 (56%), Gaps = 4/197 (2%) Frame = +1 Query: 4 AVGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYD-- 177 AVGY N+DV+ A K GI + NTPGVLT+ T R +V+ D+F R+G + Sbjct: 76 AVGYDNIDVEEATKRGIYVTNTPGVLTDATADLAFALLLATARHLVKGDKFTRSGEWKKR 135 Query: 178 --GWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTA 351 W P F+G + G+T+G+IG GRIG A A+ GF M ++Y+ + +EK + A Sbjct: 136 GVAWHPKWFLGYDVYGKTIGIIGFGRIGQAIAKRA-RGFDMRILYYSRTRKPEVEKELNA 194 Query: 352 YGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLV 531 ++E+LRE+D + L L+K TYH+IN ERL MMK+ A+L+ Sbjct: 195 ----------------EFKPLDELLRESDFVVLAVPLNKETYHMINEERLKMMKRTAILI 238 Query: 532 NASRGPVIDEVALVEHL 582 N +RG VID AL++ L Sbjct: 239 NVARGKVIDTKALIKAL 255
>GYAR_AERPE (Q9YAW4) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 335 Score = 134 bits (338), Expect = 1e-31 Identities = 79/198 (39%), Positives = 111/198 (56%), Gaps = 4/198 (2%) Frame = +1 Query: 1 MAVGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAG---- 168 MAVG+ N+DV+ A + GI + NTPGVLTE T RR+VEAD F+R G Sbjct: 75 MAVGFDNIDVECATRLGIYVTNTPGVLTEATAEFTWALILAAARRVVEADHFVRWGEWWR 134 Query: 169 LYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVT 348 L GW P + +G L+G+T+G++G GRIGS A + + F M +IY + +EK + Sbjct: 135 LRTGWHPMMMLGVELRGKTLGILGMGRIGSRVAEIG-KAFGMRIIYHSRSRKREIEKELG 193 Query: 349 AYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVL 528 A S+E++LRE+D++S+H L T HLI L +MKK A+L Sbjct: 194 A----------------EYRSLEDLLRESDILSIHLPLTDETRHLIGESELKLMKKTAIL 237 Query: 529 VNASRGPVIDEVALVEHL 582 VN RG ++D ALV+ L Sbjct: 238 VNTGRGAIVDTGALVKAL 255
>GYAR_PYRHO (O58320) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 334 Score = 133 bits (334), Expect = 4e-31 Identities = 74/197 (37%), Positives = 111/197 (56%), Gaps = 4/197 (2%) Frame = +1 Query: 4 AVGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYD-- 177 AVGY N+D++ A K GI + NTP VLT+ T R +V+ D+F+R+G + Sbjct: 75 AVGYDNIDIEEATKRGIYVTNTPDVLTDATADLAFALLLATARHVVKGDRFVRSGEWKKR 134 Query: 178 --GWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTA 351 W P F+G + G+T+G+IG GRIG A A+ +GF M ++Y+ + +E+ + A Sbjct: 135 GVAWHPKWFLGYDVYGKTIGIIGLGRIGQAIAKRA-KGFNMRILYYSRTRKEEVERELNA 193 Query: 352 YGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLV 531 +E++LRE+D + L L + TYHLIN ERL +MKK A+L+ Sbjct: 194 ----------------EFKPLEDLLRESDFVVLAVPLTRETYHLINEERLKLMKKTAILI 237 Query: 532 NASRGPVIDEVALVEHL 582 N +RG V+D ALV+ L Sbjct: 238 NIARGKVVDTNALVKAL 254
>GYAR_PYRKO (Q5JEZ2) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 333 Score = 130 bits (327), Expect = 3e-30 Identities = 76/197 (38%), Positives = 109/197 (55%), Gaps = 4/197 (2%) Frame = +1 Query: 4 AVGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYD-- 177 AVGY N+DV+ A + GI + NTP VLT+ T RR++EAD F R+G + Sbjct: 75 AVGYDNIDVEEATRRGIYVTNTPDVLTDATADFAWTLLLATARRLIEADHFTRSGEWKRR 134 Query: 178 --GWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTA 351 W P F+G + G+T+G++G GRIG A AR GF M ++Y+ + EK + A Sbjct: 135 GIAWHPRWFLGYDVYGKTIGIVGFGRIGQAVARRA-RGFGMRILYYSRSRKPEAEKELGA 193 Query: 352 YGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLV 531 S+E++LRE+D + L L K T ++IN ERL +MKK A+LV Sbjct: 194 ----------------EFRSLEDLLRESDFVVLAVPLTKETQYMINEERLRLMKKTAILV 237 Query: 532 NASRGPVIDEVALVEHL 582 N +RG V+D AL++ L Sbjct: 238 NIARGKVVDTKALMKAL 254
>GYAR_PYRFU (Q8U3Y2) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 336 Score = 128 bits (321), Expect = 1e-29 Identities = 74/197 (37%), Positives = 109/197 (55%), Gaps = 4/197 (2%) Frame = +1 Query: 4 AVGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYD-- 177 AVGY N+DV+ A + GI + NTP VLT T R +V+ D+F+R+G + Sbjct: 75 AVGYDNIDVEEATRRGIYVTNTPDVLTNATADHAFALLLATARHVVKGDKFVRSGEWKRK 134 Query: 178 --GWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTA 351 W P F+G L G+T+G++G GRIG A AR +GF M ++Y+ + ++ EK + A Sbjct: 135 GIAWHPKWFLGYELYGKTIGIVGFGRIGQAIARRA-KGFNMRILYYSRTRKSQAEKELGA 193 Query: 352 YGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLV 531 +EEVL+E+D + L L K T ++IN ERL +MK A+LV Sbjct: 194 ----------------EYRPLEEVLKESDFVILAVPLTKETMYMINEERLKLMKPTAILV 237 Query: 532 NASRGPVIDEVALVEHL 582 N +RG V+D AL++ L Sbjct: 238 NIARGKVVDTKALIKAL 254
>TKRA_ENTAG (P58000) 2-ketogluconate reductase (EC 1.1.1.215) (2KR)| (2-ketoaldonate reductase) Length = 323 Score = 103 bits (258), Expect = 3e-22 Identities = 64/194 (32%), Positives = 100/194 (51%) Frame = +1 Query: 1 MAVGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDG 180 ++VGY N DV+A N+ GI + +TP VLTET RR+VE + ++AG + Sbjct: 72 ISVGYDNFDVEALNQRGIVLIDTPTVLTETVADTMMALVLSSARRVVEVAERVKAGEWRR 131 Query: 181 WLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQ 360 + + G + + +G++G GRIG A A+ GF M ++Y E A Sbjct: 132 SIGPDWFGIDVHHKKMGILGMGRIGLALAQRAHHGFGMPILYNARKHHEEAESRFNA--- 188 Query: 361 FLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNAS 540 + ++ +LRE+D + + L + T+H+I E+LA MK A+L+NA Sbjct: 189 -------------QYCDLDTLLRESDFLCISLPLTEQTHHMIGREQLAKMKPSAILINAG 235 Query: 541 RGPVIDEVALVEHL 582 RGPV+DE AL+ L Sbjct: 236 RGPVVDEQALIAAL 249
>TKRA_ECOLI (P37666) 2-ketogluconate reductase (EC 1.1.1.215) (2KR)| (2-ketoaldonate reductase) Length = 324 Score = 100 bits (250), Expect = 2e-21 Identities = 63/194 (32%), Positives = 95/194 (48%) Frame = +1 Query: 1 MAVGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDG 180 ++VGY N DVDA I + +TP VLTET RR+VE + ++AG + Sbjct: 73 ISVGYDNFDVDALTARKILLMHTPTVLTETVADTLMALVLSTARRVVEVAERVKAGEWTA 132 Query: 181 WLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQ 360 + + G + +T+G++G GRIG A A+ GF M ++Y E+ A Sbjct: 133 SIGPDWYGTDVHHKTLGIVGMGRIGMALAQRAHFGFNMPILYNARRHHKEAEERFNA--- 189 Query: 361 FLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNAS 540 R ++ +L+E+D + L L T+HL E+ A MK A+ +NA Sbjct: 190 -------------RYCDLDTLLQESDFVCLILPLTDETHHLFGAEQFAKMKSSAIFINAG 236 Query: 541 RGPVIDEVALVEHL 582 RGPV+DE AL+ L Sbjct: 237 RGPVVDENALIAAL 250
>TKRA_ECO57 (P58220) 2-ketogluconate reductase (EC 1.1.1.215) (2KR)| (2-ketoaldonate reductase) Length = 324 Score = 100 bits (250), Expect = 2e-21 Identities = 63/194 (32%), Positives = 95/194 (48%) Frame = +1 Query: 1 MAVGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDG 180 ++VGY N DVDA I + +TP VLTET RR+VE + ++AG + Sbjct: 73 ISVGYDNFDVDALTARKILLMHTPTVLTETVADTLMALVLSTARRVVEVAERVKAGEWTA 132 Query: 181 WLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQ 360 + + G + +T+G++G GRIG A A+ GF M ++Y E+ A Sbjct: 133 SIGPDWYGTDVHHKTLGIVGMGRIGMALAQRAHFGFNMPILYNARRHHKEAEERFNA--- 189 Query: 361 FLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNAS 540 R ++ +L+E+D + L L T+HL E+ A MK A+ +NA Sbjct: 190 -------------RYCDLDTLLQESDFVCLILPLTDETHHLFGAEQFAKMKSSAIFINAG 236 Query: 541 RGPVIDEVALVEHL 582 RGPV+DE AL+ L Sbjct: 237 RGPVVDENALIAAL 250
>TKRA_BACSU (O32264) Probable 2-ketogluconate reductase (EC 1.1.1.215) (2KR)| Length = 325 Score = 98.2 bits (243), Expect = 2e-20 Identities = 58/193 (30%), Positives = 90/193 (46%) Frame = +1 Query: 4 AVGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGW 183 +VGY N D++A + G+ +TP L +T RR+ E D+F+RAG + Sbjct: 77 SVGYDNFDIEAMKERGVVGTHTPYTLDDTVADLAFSLILSSARRVAELDRFVRAGKWGTV 136 Query: 184 LPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQF 363 G + QT+G+IG GRIG AR GF M ++Y + ++ E + Sbjct: 137 EEEALFGIDVHHQTLGIIGMGRIGEQAARRAKFGFDMEVLYHNRHRKQETEDSIGV---- 192 Query: 364 LKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASR 543 + + ++ +L ++D I L L TYH+I +MK A+ VN SR Sbjct: 193 ------------KYAELDTLLEQSDFILLITPLTDETYHMIGEREFKLMKNSAIFVNISR 240 Query: 544 GPVIDEVALVEHL 582 G +DE AL+ L Sbjct: 241 GKTVDEKALIRAL 253
>SERA_METTH (O27051) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 525 Score = 95.1 bits (235), Expect = 1e-19 Identities = 65/192 (33%), Positives = 97/192 (50%) Frame = +1 Query: 7 VGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 186 VG NVDV AA GI + N P + T R+I AD+ ++ G W Sbjct: 74 VGVDNVDVKAATDRGIMVINAPESTSITVAEHSIGLMLALARKIAIADRSVKEGK---WE 130 Query: 187 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 366 + F+G L G+T+G+IG GRIGS + + F M+++ +D Y S Sbjct: 131 KNRFMGIELNGKTLGIIGMGRIGSQVV-VRTKAFGMDIMVYDPYISK------------- 176 Query: 367 KANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRG 546 +A E VT + +E +LRE+D++++H L T HLI+ + +MK A +VN +RG Sbjct: 177 EAAEEMGVT---VTDLETLLRESDIVTIHVPLTPETRHLISEDEFKLMKDTAFIVNCARG 233 Query: 547 PVIDEVALVEHL 582 +IDE AL L Sbjct: 234 GIIDEDALYRAL 245
>SERA_BACSU (P35136) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 525 Score = 93.2 bits (230), Expect = 5e-19 Identities = 62/192 (32%), Positives = 95/192 (49%) Frame = +1 Query: 7 VGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 186 VG N+D+D A K+G+ + N P T +T R I +A+ +++ W Sbjct: 71 VGVDNIDIDEATKHGVIVINAPNGNTISTAEHTFAMISSLMRHIPQANISVKSR---EWN 127 Query: 187 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 366 +VG+ L G+T+G++G GRIGS A+ F M + FD + + K + Sbjct: 128 RTAYVGSELYGKTLGIVGLGRIGSEIAQRR-GAFGMTVHVFDPFLTEERAKKIGV----- 181 Query: 367 KANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRG 546 + + EEVL AD+I++H L K T L+N E +A KK L+N +RG Sbjct: 182 -----------NSRTFEEVLESADIITVHTPLTKETKGLLNKETIAKTKKGVRLINCARG 230 Query: 547 PVIDEVALVEHL 582 +IDE AL+E L Sbjct: 231 GIIDEAALLEAL 242
>SERA_METJA (Q58424) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 524 Score = 92.4 bits (228), Expect = 8e-19 Identities = 62/192 (32%), Positives = 94/192 (48%) Frame = +1 Query: 7 VGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 186 VG N+DV+AA + GI + N P + + R I +A ++ G +D Sbjct: 72 VGVDNIDVEAATEKGIIVVNAPDASSISVAELTMGLMLAAARNIPQATASLKRGEWDR-- 129 Query: 187 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 366 F G L G+T+GVIG GRIG + + F MN+I +D Y + + + Sbjct: 130 -KRFKGIELYGKTLGVIGLGRIGQQVVKRA-KAFGMNIIGYDPYIPKEVAESMGV----- 182 Query: 367 KANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRG 546 + + E+ + AD I+LH L T H+I E++A+MKK A++VN +RG Sbjct: 183 ----------ELVDDINELCKRADFITLHVPLTPKTRHIIGREQIALMKKNAIIVNCARG 232 Query: 547 PVIDEVALVEHL 582 +IDE AL E L Sbjct: 233 GLIDEKALYEAL 244
>SERA_ARCFU (O29445) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 527 Score = 89.4 bits (220), Expect = 7e-18 Identities = 60/190 (31%), Positives = 94/190 (49%) Frame = +1 Query: 7 VGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 186 VG N+D++AA + GI + N PG T +T R+I +AD+ ++ G W Sbjct: 72 VGVDNIDINAATQRGIVVVNAPGGNTISTAEHAIALMLAAARKIPQADRSVKEGK---WE 128 Query: 187 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 366 F+G L+G+T GVIG GR+G A+ + +MN++ +D + S Sbjct: 129 RKKFMGIELRGKTAGVIGLGRVGFEVAKRC-KALEMNVLAYDPFVS-------------- 173 Query: 367 KANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRG 546 K EQ + + +L +DVI++H K T LI + MK ++VNA+RG Sbjct: 174 KERAEQ--IGVKLVDFDTLLASSDVITVHVPRTKETIGLIGKGQFEKMKDGVIVVNAARG 231 Query: 547 PVIDEVALVE 576 ++DE AL E Sbjct: 232 GIVDEAALYE 241
>CTBPB_XENLA (Q9W758) C-terminal-binding protein B (TCF-3 corepressor CtBP)| (XCtBP) Length = 437 Score = 89.0 bits (219), Expect = 9e-18 Identities = 58/195 (29%), Positives = 98/195 (50%), Gaps = 4/195 (2%) Frame = +1 Query: 10 GYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 189 GY N+D+ +A + GIA+ N P E T RR+ Q MR G + Sbjct: 104 GYDNIDIKSAAELGIAVCNIPSASVEETADSTLCHILNLYRRVTWLHQAMREGNRPASVE 163 Query: 190 HL--FVGNL--LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYG 357 + G ++G+T+G+IG GRIG A A + + F +I++D Y + +E+ + Sbjct: 164 QIREVAGGAARIRGETLGIIGLGRIGQAVA-LRAKAFNFTVIFYDPYLADGVERSLGL-- 220 Query: 358 QFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 537 +R ++++E+L +D I+LH L++ +HLIN + M++ LVN Sbjct: 221 -------------QRMATLQELLMHSDCITLHCNLNEHNHHLINDFTIKQMRQGCFLVNT 267 Query: 538 SRGPVIDEVALVEHL 582 +RG ++DE AL + L Sbjct: 268 ARGGLVDEKALAQAL 282
>DDH_ZYMMO (P30799) 2-hydroxyacid dehydrogenase homolog (EC 1.1.1.-)| Length = 331 Score = 88.2 bits (217), Expect = 2e-17 Identities = 63/197 (31%), Positives = 90/197 (45%), Gaps = 6/197 (3%) Frame = +1 Query: 10 GYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRI------VEADQFMRAGL 171 GY NVD+DAA K I + P + R+I V + F GL Sbjct: 78 GYNNVDLDAAKKLNIKVVRVPAYSPYSVAEYAVGMLLTLNRQISRGLKRVRENNFSLEGL 137 Query: 172 YDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTA 351 +G + +TVG+IG G IGS +A +M GF N+I + + L K V Sbjct: 138 ---------IGLDVHDKTVGIIGVGHIGSVFAHIMTHGFGANVIAYKPHPDPELAKKVGF 188 Query: 352 YGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLV 531 R +S++EV+ +D+ISLH L +H+IN E LA KK LV Sbjct: 189 ----------------RFTSLDEVIETSDIISLHCPLTPENHHMINEETLARAKKGFYLV 232 Query: 532 NASRGPVIDEVALVEHL 582 N SRG ++D A+++ L Sbjct: 233 NTSRGGLVDTKAVIKSL 249
>PTXD_PSEST (O69054) Phosphonate dehydrogenase (EC 1.20.1.1) (NAD-dependent| phosphite dehydrogenase) Length = 336 Score = 87.0 bits (214), Expect = 3e-17 Identities = 61/191 (31%), Positives = 91/191 (47%) Frame = +1 Query: 10 GYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 189 G+ N DVDA G+ + P +LT T R + AD F+R+G + GW P Sbjct: 77 GFDNFDVDACTARGVWLTFVPDLLTVPTAELAIGLAVGLGRHLRAADAFVRSGEFQGWQP 136 Query: 190 HLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLK 369 F G L TVG++G G IG A A + +G+ L Y + + L Sbjct: 137 Q-FYGTGLDNATVGILGMGAIGLAMADRL-QGWGATLQYHE--------------AKALD 180 Query: 370 ANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGP 549 EQ + ++ + E+ +D I L L+ T HL+N E LA+++ A+LVN RG Sbjct: 181 TQTEQRLGLRQVAC-SELFASSDFILLALPLNADTQHLVNAELLALVRPGALLVNPCRGS 239 Query: 550 VIDEVALVEHL 582 V+DE A++ L Sbjct: 240 VVDEAAVLAAL 250
>CTBP1_RAT (Q9Z2F5) C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1)| (C-terminal-binding protein 3) (CtBP3) (50 kDa BFA-dependent ADP-ribosylation substrate) (BARS-50) Length = 430 Score = 86.3 bits (212), Expect = 6e-17 Identities = 58/195 (29%), Positives = 98/195 (50%), Gaps = 4/195 (2%) Frame = +1 Query: 10 GYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 189 G+ N+D+ +A GIA+ N P E T RR Q +R G + Sbjct: 90 GFDNIDIKSAGDLGIAVCNVPAASVEETADSTLCHILNLYRRTTWLHQALREGTRVQSVE 149 Query: 190 HLFV----GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYG 357 + ++G+T+G+IG GR+G A A + + F N++++D Y S +E+ Sbjct: 150 QIREVASGAARIRGETLGIIGLGRVGQAVA-LRAKAFGFNVLFYDPYLSDGIER------ 202 Query: 358 QFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 537 A G Q R S+++++L +D ++LH L++ +HLIN + M++ A LVN Sbjct: 203 ----ALGLQ-----RVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNT 253 Query: 538 SRGPVIDEVALVEHL 582 +RG ++DE AL + L Sbjct: 254 ARGGLVDEKALAQAL 268
>CTBP1_MOUSE (O88712) C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1)| Length = 440 Score = 86.3 bits (212), Expect = 6e-17 Identities = 58/195 (29%), Positives = 98/195 (50%), Gaps = 4/195 (2%) Frame = +1 Query: 10 GYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 189 G+ N+D+ +A GIA+ N P E T RR Q +R G + Sbjct: 101 GFDNIDIKSAGDLGIAVCNVPAASVEETADSTLCHILNLYRRTTWLHQALREGTRVQSVE 160 Query: 190 HLFV----GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYG 357 + ++G+T+G+IG GR+G A A + + F N++++D Y S +E+ Sbjct: 161 QIREVASGAARIRGETLGIIGLGRVGQAVA-LRAKAFGFNVLFYDPYLSDGIER------ 213 Query: 358 QFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 537 A G Q R S+++++L +D ++LH L++ +HLIN + M++ A LVN Sbjct: 214 ----ALGLQ-----RVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNT 264 Query: 538 SRGPVIDEVALVEHL 582 +RG ++DE AL + L Sbjct: 265 ARGGLVDEKALAQAL 279
>SERA_MYCLE (O33116) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 528 Score = 86.3 bits (212), Expect = 6e-17 Identities = 63/190 (33%), Positives = 86/190 (45%) Frame = +1 Query: 7 VGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 186 VG NVDVDAA G+ + N P + R+I EAD +RA + W Sbjct: 74 VGLDNVDVDAATARGVLVVNAPTSNIHSAAEHALALLLAASRQIAEADASLRAHI---WK 130 Query: 187 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 366 F G + G+TVGV+G GRIG A I F ++I +D Y Sbjct: 131 RSSFSGTEIFGKTVGVVGLGRIGQLVAAR-IAAFGAHVIAYDPYV--------------- 174 Query: 367 KANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRG 546 A S +++L AD IS+H T LI+ E LA K ++VNA+RG Sbjct: 175 -APARAAQLGIELMSFDDLLARADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARG 233 Query: 547 PVIDEVALVE 576 ++DEVAL + Sbjct: 234 GLVDEVALAD 243
>CTBP1_HUMAN (Q13363) C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1)| Length = 440 Score = 85.9 bits (211), Expect = 8e-17 Identities = 58/195 (29%), Positives = 98/195 (50%), Gaps = 4/195 (2%) Frame = +1 Query: 10 GYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 189 G+ N+D+ +A GIA+ N P E T RR Q +R G + Sbjct: 101 GFDNIDIKSAGDLGIAVCNVPAASVEETADSTLCHILNLYRRATWLHQALREGTRVQSVE 160 Query: 190 HLFV----GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYG 357 + ++G+T+G+IG GR+G A A + + F N++++D Y S +E+ Sbjct: 161 QIREVASGAARIRGETLGIIGLGRVGQAVA-LRAKAFGFNVLFYDPYLSDGVER------ 213 Query: 358 QFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 537 A G Q R S+++++L +D ++LH L++ +HLIN + M++ A LVN Sbjct: 214 ----ALGLQ-----RVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNT 264 Query: 538 SRGPVIDEVALVEHL 582 +RG ++DE AL + L Sbjct: 265 ARGGLVDEKALAQAL 279
>CTBPA_XENLA (Q9YHU0) C-terminal-binding protein A (CtBP)| Length = 440 Score = 85.1 bits (209), Expect = 1e-16 Identities = 58/195 (29%), Positives = 97/195 (49%), Gaps = 4/195 (2%) Frame = +1 Query: 10 GYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 189 G+ N+D+ +A GIA+ N P E T RR Q +R G + Sbjct: 101 GFDNIDIKSAGDLGIAVCNVPAASVEETADSTMCHILNLYRRTTWLHQALREGTRVQSVE 160 Query: 190 HLFV----GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYG 357 + ++G+T+G+IG GR+G A A + + F N+ ++D Y S +E+ Sbjct: 161 QIREVASGAARIRGETLGIIGLGRVGQAVA-LRAKTFGFNVFFYDPYLSDGIER------ 213 Query: 358 QFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 537 A G Q R S+++++L +D ++LH L++ +HLIN + M++ A LVN Sbjct: 214 ----ALGLQ-----RVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTIKQMRQGAFLVNT 264 Query: 538 SRGPVIDEVALVEHL 582 +RG ++DE AL + L Sbjct: 265 ARGGLVDEKALAQAL 279
>LDHD_LACDE (P26297) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 332 Score = 85.1 bits (209), Expect = 1e-16 Identities = 57/193 (29%), Positives = 95/193 (49%), Gaps = 1/193 (0%) Frame = +1 Query: 7 VGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYD-GW 183 VG N+D+ A + G I N P R+ D+ + +D W Sbjct: 78 VGVDNIDMAKAKELGFQITNVPVYSPNAIAEHAAIQAARILRQAKAMDE--KVARHDLRW 135 Query: 184 LPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQF 363 P +G ++ Q VGV+G G IG + ++M EGF +I +D++++ LEK G + Sbjct: 136 APT--IGREVRDQVVGVVGTGHIGQVFMQIM-EGFGAKVIAYDIFRNPELEK----KGYY 188 Query: 364 LKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASR 543 + S++++ ++ADVISLH H+IN + +A MK++ V+VN SR Sbjct: 189 V-------------DSLDDLYKQADVISLHVPDVPANVHMINDKSIAKMKQDVVIVNVSR 235 Query: 544 GPVIDEVALVEHL 582 GP++D A++ L Sbjct: 236 GPLVDTDAVIRGL 248
>CTBP2_MOUSE (P56546) C-terminal-binding protein 2 (CtBP2)| Length = 445 Score = 84.7 bits (208), Expect = 2e-16 Identities = 58/195 (29%), Positives = 97/195 (49%), Gaps = 4/195 (2%) Frame = +1 Query: 10 GYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 189 GY NVD+ AA + GIA+ N P E T RR Q +R G + Sbjct: 107 GYDNVDIKAAGELGIAVCNIPSAAVEETADSTVCHILNLYRRNTWLYQALREGTRVQSVE 166 Query: 190 HLFV----GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYG 357 + ++G+T+G+IG GR G A A + + F ++I++D Y +E+ + Sbjct: 167 QIREVASGAARIRGETLGLIGFGRTGQAVA-VRAKAFGFSVIFYDPYLQDGIERSLGV-- 223 Query: 358 QFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 537 +R +++++L ++D +SLH L++ +HLIN + M++ A LVNA Sbjct: 224 -------------QRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNA 270 Query: 538 SRGPVIDEVALVEHL 582 +RG ++DE AL + L Sbjct: 271 ARGGLVDEKALAQAL 285
>CTBP2_HUMAN (P56545) C-terminal-binding protein 2 (CtBP2)| Length = 445 Score = 84.7 bits (208), Expect = 2e-16 Identities = 58/195 (29%), Positives = 97/195 (49%), Gaps = 4/195 (2%) Frame = +1 Query: 10 GYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 189 GY NVD+ AA + GIA+ N P E T RR Q +R G + Sbjct: 107 GYDNVDIKAAGELGIAVCNIPSAAVEETADSTICHILNLYRRNTWLYQALREGTRVQSVE 166 Query: 190 HLFV----GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYG 357 + ++G+T+G+IG GR G A A + + F ++I++D Y +E+ + Sbjct: 167 QIREVASGAARIRGETLGLIGFGRTGQAVA-VRAKAFGFSVIFYDPYLQDGIERSLGV-- 223 Query: 358 QFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 537 +R +++++L ++D +SLH L++ +HLIN + M++ A LVNA Sbjct: 224 -------------QRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNA 270 Query: 538 SRGPVIDEVALVEHL 582 +RG ++DE AL + L Sbjct: 271 ARGGLVDEKALAQAL 285
>LDHD_ECOLI (P52643) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH)| (Fermentative lactate dehydrogenase) Length = 329 Score = 83.6 bits (205), Expect = 4e-16 Identities = 63/191 (32%), Positives = 85/191 (44%) Frame = +1 Query: 10 GYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 189 G+ NVD+DAA + G+ + P E RRI A Q R + L Sbjct: 78 GFNNVDLDAAKELGLKVVRVPAYDPEAVAEHAIGMMMTLNRRIHRAYQRTRDANFS--LE 135 Query: 190 HLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLK 369 L G + G+T GVIG G+IG A R++ +GF M L+ FD Y S + Y Sbjct: 136 GL-TGFTMYGKTAGVIGTGKIGVAMLRIL-KGFGMRLLAFDPYPSAAALELGVEY----- 188 Query: 370 ANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGP 549 + + E+DVISLH L YHL+N MK ++VN SRG Sbjct: 189 ------------VDLPTLFSESDVISLHCPLTPENYHLLNEAAFEQMKNGVMIVNTSRGA 236 Query: 550 VIDEVALVEHL 582 +ID A +E L Sbjct: 237 LIDSQAAIEAL 247
>LDHD_STAAR (Q6GDS2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 83.2 bits (204), Expect = 5e-16 Identities = 59/189 (31%), Positives = 95/189 (50%) Frame = +1 Query: 10 GYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 189 G+ D+D A K+ I I N P ET RR + ++ ++A + W Sbjct: 79 GFDMYDLDLAKKHNIVISNVPSYSPETIAEYSVSIALQLVRRFPDIERRVQAHDFT-WQA 137 Query: 190 HLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLK 369 + + +K TV +IG GRIG+A A++ GF + +D Y + L+ FL Sbjct: 138 EI-MSKPVKNMTVAIIGTGRIGAATAKIYA-GFGATITAYDAYPNKDLD--------FL- 186 Query: 370 ANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGP 549 T+K S++E +++AD+ISLH +K +YHL + +KK A+LVNA+RG Sbjct: 187 -------TYK--DSVKEAIKDADIISLHVPANKESYHLFDKTMFDHVKKGAILVNAARGA 237 Query: 550 VIDEVALVE 576 VI+ L++ Sbjct: 238 VINTPDLID 246
>LDHD_LACHE (P30901) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 336 Score = 83.2 bits (204), Expect = 5e-16 Identities = 59/192 (30%), Positives = 92/192 (47%) Frame = +1 Query: 7 VGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 186 VG N+D+D A + G I N P R+ D+ M A W Sbjct: 78 VGVDNIDMDKAKELGFQITNVPVYSPNAIAEHAAIQAARVLRQDKRMDEKM-AKRDLRWA 136 Query: 187 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 366 P +G ++ Q VGV+G G IG + R+M EGF +I +D++++ LEK G ++ Sbjct: 137 PT--IGREVRDQVVGVVGTGHIGQVFMRIM-EGFGAKVIAYDIFKNPELEK----KGYYV 189 Query: 367 KANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRG 546 S++++ ++ADVISLH H+IN + +A MK V+VN SRG Sbjct: 190 -------------DSLDDLYKQADVISLHVPDVPANVHMINDKSIAEMKDGVVIVNCSRG 236 Query: 547 PVIDEVALVEHL 582 ++D A++ L Sbjct: 237 RLVDTDAVIRGL 248
>DDH_HAEIN (P44501) 2-hydroxyacid dehydrogenase homolog (EC 1.1.1.-)| Length = 331 Score = 83.2 bits (204), Expect = 5e-16 Identities = 61/191 (31%), Positives = 96/191 (50%) Frame = +1 Query: 10 GYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 189 G+ NVD+ AA + GI + P E RRI A Q R + L Sbjct: 78 GFNNVDLKAAQELGIQVVRVPAYSPEAVAEHTIGLMMTLNRRIHRAYQRTREANFS--LE 135 Query: 190 HLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLK 369 L +G + G+TVGVIG G+IG A R++ +GF MN++ +D +++ +E+ GQ+++ Sbjct: 136 GL-IGFNMYGRTVGVIGTGKIGIAVMRIL-KGFGMNILAYDPFKNPVVEELG---GQYVE 190 Query: 370 ANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGP 549 ++E+ ++ VI+LH YHL+N E A MK ++VN SRG Sbjct: 191 --------------LDELYAKSHVITLHCPATPENYHLLNCEAFAKMKDGVMIVNTSRGS 236 Query: 550 VIDEVALVEHL 582 +ID A ++ L Sbjct: 237 LIDTQAAIDAL 247
>LDHD_STAAW (Q8NUT2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 82.4 bits (202), Expect = 9e-16 Identities = 59/188 (31%), Positives = 94/188 (50%) Frame = +1 Query: 10 GYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 189 G+ D+D A K+ I I N P ET RR + ++ ++A + W Sbjct: 79 GFDMYDLDLAKKHNIVISNVPSYSPETIAEYSVSIALQLVRRFPDIERRVQAHDFT-WQA 137 Query: 190 HLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLK 369 + + +K TV +IG GRIG+A A++ GF + +D Y + L+ FL Sbjct: 138 EI-MSKPVKNMTVAIIGTGRIGAATAKIYA-GFGATITAYDAYPNKDLD--------FL- 186 Query: 370 ANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGP 549 T+K S++E +++AD+ISLH +K +YHL + +KK A+LVNA+RG Sbjct: 187 -------TYK--DSVKEAIKDADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGA 237 Query: 550 VIDEVALV 573 VI+ L+ Sbjct: 238 VINTPDLI 245
>LDHD_STAAU (P72357) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 82.4 bits (202), Expect = 9e-16 Identities = 59/188 (31%), Positives = 94/188 (50%) Frame = +1 Query: 10 GYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 189 G+ D+D A K+ I I N P ET RR + ++ ++A + W Sbjct: 79 GFDMYDLDLAKKHNIVISNVPSYSPETIAEYSVSIALQLVRRFPDIERRVQAHDFT-WQA 137 Query: 190 HLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLK 369 + + +K TV +IG GRIG+A A++ GF + +D Y + L+ FL Sbjct: 138 EI-MSKPVKNMTVAIIGTGRIGAATAKIYA-GFGATITAYDAYPNKDLD--------FL- 186 Query: 370 ANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGP 549 T+K S++E +++AD+ISLH +K +YHL + +KK A+LVNA+RG Sbjct: 187 -------TYK--DSVKEAIKDADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGA 237 Query: 550 VIDEVALV 573 VI+ L+ Sbjct: 238 VINTPDLI 245
>LDHD_STAAS (Q6G6F1) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 82.4 bits (202), Expect = 9e-16 Identities = 59/188 (31%), Positives = 94/188 (50%) Frame = +1 Query: 10 GYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 189 G+ D+D A K+ I I N P ET RR + ++ ++A + W Sbjct: 79 GFDMYDLDLAKKHNIVISNVPSYSPETIAEYSVSIALQLVRRFPDIERRVQAHDFT-WQA 137 Query: 190 HLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLK 369 + + +K TV +IG GRIG+A A++ GF + +D Y + L+ FL Sbjct: 138 EI-MSKPVKNMTVAIIGTGRIGAATAKIYA-GFGATITAYDAYPNKDLD--------FL- 186 Query: 370 ANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGP 549 T+K S++E +++AD+ISLH +K +YHL + +KK A+LVNA+RG Sbjct: 187 -------TYK--DSVKEAIKDADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGA 237 Query: 550 VIDEVALV 573 VI+ L+ Sbjct: 238 VINTPDLI 245
>LDHD_STAAC (Q5HD29) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 82.4 bits (202), Expect = 9e-16 Identities = 59/188 (31%), Positives = 94/188 (50%) Frame = +1 Query: 10 GYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 189 G+ D+D A K+ I I N P ET RR + ++ ++A + W Sbjct: 79 GFDMYDLDLAKKHNIVISNVPSYSPETIAEYSVSIALQLVRRFPDIERRVQAHDFT-WQA 137 Query: 190 HLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLK 369 + + +K TV +IG GRIG+A A++ GF + +D Y + L+ FL Sbjct: 138 EI-MSKPVKNMTVAIIGTGRIGAATAKIYA-GFGATITAYDAYPNKDLD--------FL- 186 Query: 370 ANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGP 549 T+K S++E +++AD+ISLH +K +YHL + +KK A+LVNA+RG Sbjct: 187 -------TYK--DSVKEAIKDADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGA 237 Query: 550 VIDEVALV 573 VI+ L+ Sbjct: 238 VINTPDLI 245
>LDHD_STAAN (P99116) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 82.0 bits (201), Expect = 1e-15 Identities = 59/188 (31%), Positives = 91/188 (48%) Frame = +1 Query: 10 GYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 189 G+ D+D A K+ I I N P ET RR + ++ R +D Sbjct: 79 GFDMYDLDLAKKHNIVISNVPSYSPETIAEYSVSIALQLVRRFPDIER--RVQTHDFTWQ 136 Query: 190 HLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLK 369 + +K TV +IG GRIG+A A++ GF + +D Y + L+ FL Sbjct: 137 AEIMSKPVKNMTVAIIGTGRIGAATAKIYA-GFGATITAYDAYPNKDLD--------FL- 186 Query: 370 ANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGP 549 T+K S++E +++AD+ISLH +K +YHL + +KK A+LVNA+RG Sbjct: 187 -------TYK--DSVKEAIKDADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGA 237 Query: 550 VIDEVALV 573 VI+ L+ Sbjct: 238 VINTPDLI 245
>LDHD_STAAM (P63940) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 82.0 bits (201), Expect = 1e-15 Identities = 59/188 (31%), Positives = 91/188 (48%) Frame = +1 Query: 10 GYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 189 G+ D+D A K+ I I N P ET RR + ++ R +D Sbjct: 79 GFDMYDLDLAKKHNIVISNVPSYSPETIAEYSVSIALQLVRRFPDIER--RVQTHDFTWQ 136 Query: 190 HLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLK 369 + +K TV +IG GRIG+A A++ GF + +D Y + L+ FL Sbjct: 137 AEIMSKPVKNMTVAIIGTGRIGAATAKIYA-GFGATITAYDAYPNKDLD--------FL- 186 Query: 370 ANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGP 549 T+K S++E +++AD+ISLH +K +YHL + +KK A+LVNA+RG Sbjct: 187 -------TYK--DSVKEAIKDADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGA 237 Query: 550 VIDEVALV 573 VI+ L+ Sbjct: 238 VINTPDLI 245
>SERA_ARATH (O04130) D-3-phosphoglycerate dehydrogenase, chloroplast precursor| (EC 1.1.1.95) (3-PGDH) Length = 624 Score = 82.0 bits (201), Expect = 1e-15 Identities = 62/192 (32%), Positives = 88/192 (45%) Frame = +1 Query: 7 VGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 186 VG NVD+ AA ++G + N P T R + +AD ++AG W Sbjct: 154 VGIDNVDLQAATEHGCLVVNAPTANTVAAAEHGIALLASMARNVAQADASIKAGK---WE 210 Query: 187 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 366 +VG L G+T+ V+G G++G+ AR +G M +I D Y A Sbjct: 211 RSKYVGVSLVGKTLAVMGFGKVGTEVARRA-KGLGMTVISHDPY----------APADRA 259 Query: 367 KANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRG 546 +A G V S ++ + AD +SLH L T + N E + MKK L+N +RG Sbjct: 260 RALGVDLV------SFDQAISTADFVSLHMPLTPATKKVFNDETFSKMKKGVRLINVARG 313 Query: 547 PVIDEVALVEHL 582 VIDE ALV L Sbjct: 314 GVIDEDALVRAL 325
>DHGY_HYPME (P36234) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-dependent| hydroxypyruvate reductase) (HPR) (GDH) (Hydroxypyruvate dehydrogenase) (Glyoxylate reductase) Length = 321 Score = 82.0 bits (201), Expect = 1e-15 Identities = 50/193 (25%), Positives = 90/193 (46%) Frame = +1 Query: 4 AVGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGW 183 ++G+ ++D+DA GI +GN P +T T RR E ++ +R + GW Sbjct: 76 SIGFDHIDLDACKARGIKVGNAPHGVTVATAEIAMLLLLGSARRAGEGEKMIRTRSWPGW 135 Query: 184 LPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQF 363 P VG L +T+G+ G G IG A A+ +GF M++ YFD ++++ Sbjct: 136 EPLELVGEKLDNKTLGIYGFGSIGQALAK-RAQGFDMDIDYFDTHRAS------------ 182 Query: 364 LKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASR 543 ++ E S++ +L + SL+ T + N + + + A++VN +R Sbjct: 183 --SSDEASYQATFHDSLDSLLSVSQFFSLNAPSTPETRYFFNKATIKSLPQGAIVVNTAR 240 Query: 544 GPVIDEVALVEHL 582 G ++D +V L Sbjct: 241 GDLVDNELVVAAL 253
>YGDH_SCHPO (O94574) Putative 2-hydroxyacid dehydrogenase C1773.17c (EC| 1.-.-.-) Length = 340 Score = 80.9 bits (198), Expect = 2e-15 Identities = 58/191 (30%), Positives = 92/191 (48%) Frame = +1 Query: 4 AVGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGW 183 A GY NVDVD A +NG+ + NTP TE T R EA+Q +R G W Sbjct: 91 AAGYNNVDVDWATRNGVYVANTPNGPTEGTANMNLMLFMCTLRGAREAEQSLRLG---KW 147 Query: 184 LPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQF 363 +L + + G+ VG+IG G IG ++A+ ++ ++Y + RLE Sbjct: 148 RQNLSLTDDPYGKRVGIIGMGAIGKSFAQKILP-LGCEIVY---HNRNRLEA-------- 195 Query: 364 LKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASR 543 E+ S +E+L +DVIS++ L T+ LI+ + MK ++N +R Sbjct: 196 ----EEEKRLGASFVSFDELLSSSDVISINCPLTPATHDLISTKEFEKMKDGVYIINTAR 251 Query: 544 GPVIDEVALVE 576 G +I+E A ++ Sbjct: 252 GAIINEDAFIK 262
>GRHPR_HUMAN (Q9UBQ7) Glyoxylate reductase/hydroxypyruvate reductase (EC| 1.1.1.79) Length = 328 Score = 80.1 bits (196), Expect = 4e-15 Identities = 59/194 (30%), Positives = 88/194 (45%) Frame = +1 Query: 1 MAVGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDG 180 M+VG ++ +D K GI +G TP VLT+TT RR+ EA + ++ G + Sbjct: 81 MSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTS 140 Query: 181 WLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQ 360 W P G L TVG+IG GRIG A AR + +Y + R E+ + Sbjct: 141 WKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTG--RQPRPEEAAEFQAE 198 Query: 361 FLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNAS 540 F+ S E+ ++D I + L T L N + MK+ AV +N S Sbjct: 199 FV--------------STPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINIS 244 Query: 541 RGPVIDEVALVEHL 582 RG V+++ L + L Sbjct: 245 RGDVVNQDDLYQAL 258
>SERA_MYCTU (P0A544) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 528 Score = 79.0 bits (193), Expect = 9e-15 Identities = 61/190 (32%), Positives = 85/190 (44%) Frame = +1 Query: 7 VGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 186 VG NVDVDAA G+ + N P + R+I AD +R W Sbjct: 74 VGLDNVDVDAATARGVLVVNAPTSNIHSAAEHALALLLAASRQIPAADASLREHT---WK 130 Query: 187 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 366 F G + G+TVGV+G GRIG A+ I F ++ +D Y S Sbjct: 131 RSSFSGTEIFGKTVGVVGLGRIGQLVAQR-IAAFGAYVVAYDPYVSP------------- 176 Query: 367 KANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRG 546 A Q S++++L AD IS+H T LI+ E LA K ++VNA+RG Sbjct: 177 -ARAAQ--LGIELLSLDDLLARADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARG 233 Query: 547 PVIDEVALVE 576 ++DE AL + Sbjct: 234 GLVDEAALAD 243
>SERA_MYCBO (P0A545) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 528 Score = 79.0 bits (193), Expect = 9e-15 Identities = 61/190 (32%), Positives = 85/190 (44%) Frame = +1 Query: 7 VGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 186 VG NVDVDAA G+ + N P + R+I AD +R W Sbjct: 74 VGLDNVDVDAATARGVLVVNAPTSNIHSAAEHALALLLAASRQIPAADASLREHT---WK 130 Query: 187 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 366 F G + G+TVGV+G GRIG A+ I F ++ +D Y S Sbjct: 131 RSSFSGTEIFGKTVGVVGLGRIGQLVAQR-IAAFGAYVVAYDPYVSP------------- 176 Query: 367 KANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRG 546 A Q S++++L AD IS+H T LI+ E LA K ++VNA+RG Sbjct: 177 -ARAAQ--LGIELLSLDDLLARADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARG 233 Query: 547 PVIDEVALVE 576 ++DE AL + Sbjct: 234 GLVDEAALAD 243
>LDHD_PEDAC (Q59642) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 331 Score = 78.6 bits (192), Expect = 1e-14 Identities = 59/192 (30%), Positives = 91/192 (47%) Frame = +1 Query: 7 VGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 186 VG NV DA KN I I N P R+I E + M G Y W Sbjct: 77 VGLDNVPADALKKNDIKISNVPAYSPRAIAELSVTQLLALLRKIPEFEYKMAHGDYR-WE 135 Query: 187 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 366 P +G L TVGVIG GRIG A A + + F +I +D++++ LEK G ++ Sbjct: 136 PD--IGLELNQMTVGVIGTGRIGRA-AIDIFKPFGAKVIAYDVFRNPALEK----EGMYV 188 Query: 367 KANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRG 546 ++EE+ ++A+VI+LH K YH+++ + M+ ++N +RG Sbjct: 189 -------------DTLEELYQQANVITLHVPALKDNYHMLDEKAFGQMQDGTFILNFARG 235 Query: 547 PVIDEVALVEHL 582 ++D AL++ L Sbjct: 236 TLVDTPALLKAL 247
>LDHD_TREPA (O83080) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 331 Score = 78.2 bits (191), Expect = 2e-14 Identities = 57/191 (29%), Positives = 86/191 (45%) Frame = +1 Query: 10 GYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 189 G+ + K+GI + N P R E + F+R + P Sbjct: 79 GFDMYNATLLKKHGIRLTNVPSYSPNAIGEYALAAALQLTRHAREIETFVRKRDFRWQKP 138 Query: 190 HLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLK 369 L L+ VG++G GRIG A AR+ +G ++ FD Y + ++++T Sbjct: 139 IL--SKELRCSRVGILGTGRIGQAAARLF-KGVGAQVVGFDPYPNDAAKEWLTYV----- 190 Query: 370 ANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGP 549 SM+E+L +DVISLH K ++HLIN + +A MK LVN +RG Sbjct: 191 -------------SMDELLSTSDVISLHMPATKDSHHLINAKTIAQMKDGVYLVNTARGA 237 Query: 550 VIDEVALVEHL 582 VID AL++ L Sbjct: 238 VIDSQALLDSL 248
>CTBP_DROME (O46036) C-terminal-binding protein (CtBP protein) (dCtBP)| Length = 476 Score = 76.6 bits (187), Expect = 5e-14 Identities = 56/198 (28%), Positives = 90/198 (45%), Gaps = 11/198 (5%) Frame = +1 Query: 10 GYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 189 G N+DV AA + GIA+ N PG E RR +R G Sbjct: 101 GTDNIDVKAAGELGIAVCNVPGYGVEEVADTTMCLILNLYRRTYWLANMVREG------- 153 Query: 190 HLFVGN-----------LLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLE 336 F G ++G T+G++G GRIGSA A + + F N+I++D Y ++ Sbjct: 154 KKFTGPEQVREAAHGCARIRGDTLGLVGLGRIGSAVA-LRAKAFGFNVIFYDPYLPDGID 212 Query: 337 KFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKK 516 K + R +++++L ++D +SLH L++ +HLIN + M+ Sbjct: 213 KSLGL---------------TRVYTLQDLLFQSDCVSLHCTLNEHNHHLINEFTIKQMRP 257 Query: 517 EAVLVNASRGPVIDEVAL 570 A LVN +RG ++D+ L Sbjct: 258 GAFLVNTARGGLVDDETL 275
>GRHPR_MOUSE (Q91Z53) Glyoxylate reductase/hydroxypyruvate reductase (EC| 1.1.1.79) Length = 328 Score = 76.3 bits (186), Expect = 6e-14 Identities = 59/200 (29%), Positives = 86/200 (43%), Gaps = 6/200 (3%) Frame = +1 Query: 1 MAVGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDG 180 ++VG ++ +D K GI +G TPGVLT+ T RR+ EA + ++ G + Sbjct: 81 LSVGVDHLALDEIKKRGIRVGYTPGVLTDATAELAVSLLLTTCRRLPEAIEEVKNGGWSS 140 Query: 181 WLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQ 360 W P G L TVG++G GRIG A AR RL+ F Q Sbjct: 141 WSPLWMCGYGLSQSTVGIVGLGRIGQAIAR-------------------RLKPFGV---Q 178 Query: 361 FLKANGEQPVTWKRASSMEE------VLREADVISLHPVLDKTTYHLINPERLAMMKKEA 522 G QP + A E + E+D I + L T L + + MK A Sbjct: 179 RFLYTGRQPRPQEAAEFQAEFVPIAQLAAESDFIVVSCSLTPDTMGLCSKDFFQKMKNTA 238 Query: 523 VLVNASRGPVIDEVALVEHL 582 + +N SRG V+++ L + L Sbjct: 239 IFINISRGDVVNQEDLYQAL 258
>LDHD_STAES (Q8CN22) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 75.9 bits (185), Expect = 8e-14 Identities = 54/189 (28%), Positives = 90/189 (47%) Frame = +1 Query: 10 GYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 189 G+ D++ A K+ I I N P ET R+ ++ ++A + P Sbjct: 79 GFDMYDLELAKKHEIIISNIPSYSPETIAEYSVSIALQLVRKFPTIEKRVQAHNFTWASP 138 Query: 190 HLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLK 369 + +K TV +IG GRIG+A ++ GF ++ +D Y + L FL+ Sbjct: 139 --IMSRPVKNMTVAIIGTGRIGAATGKIYA-GFGARVVGYDAYPNHSLS--------FLE 187 Query: 370 ANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGP 549 ++E+ +++AD+ISLH +K ++HL + +KK AVLVNA+RG Sbjct: 188 YK----------ETVEDAIKDADIISLHVPANKDSFHLFDNNMFKNVKKGAVLVNAARGA 237 Query: 550 VIDEVALVE 576 VI+ L+E Sbjct: 238 VINTPDLIE 246
>LDHD_STAEQ (Q5HLA0) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 75.9 bits (185), Expect = 8e-14 Identities = 54/189 (28%), Positives = 90/189 (47%) Frame = +1 Query: 10 GYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 189 G+ D++ A K+ I I N P ET R+ ++ ++A + P Sbjct: 79 GFDMYDLELAKKHEIIISNIPSYSPETIAEYSVSIALQLVRKFPTIEKRVQAHNFTWASP 138 Query: 190 HLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLK 369 + +K TV +IG GRIG+A ++ GF ++ +D Y + L FL+ Sbjct: 139 --IMSRPVKNMTVAIIGTGRIGAATGKIYA-GFGARVVGYDAYPNHSLS--------FLE 187 Query: 370 ANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGP 549 ++E+ +++AD+ISLH +K ++HL + +KK AVLVNA+RG Sbjct: 188 YK----------ETVEDAIKDADIISLHVPANKDSFHLFDNNMFKNVKKGAVLVNAARGA 237 Query: 550 VIDEVALVE 576 VI+ L+E Sbjct: 238 VINTPDLIE 246
>SERA_HAEIN (P43885) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 410 Score = 75.5 bits (184), Expect = 1e-13 Identities = 53/192 (27%), Positives = 92/192 (47%) Frame = +1 Query: 7 VGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 186 +G VD++AA GI + N P T + R + +A+ + G+ W Sbjct: 85 IGTNQVDLNAAKARGIPVFNAPFSNTRSVAELVLGEILLLMRNVPQANAEVHRGV---WN 141 Query: 187 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 366 + ++G+ +G+IG G IGS + ++ E M++ ++D+ L Sbjct: 142 KSATGSHEVRGKKLGIIGYGHIGSQLS-IIAESLGMDVYFYDIENKLPLGNA-------- 192 Query: 367 KANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRG 546 K+ S+EE+L DV+SLH +T +L+N R+A +K+ A+L+NA+RG Sbjct: 193 ----------KQVRSLEELLSSCDVVSLHVPELPSTKNLMNVARIAQLKQGAILINAARG 242 Query: 547 PVIDEVALVEHL 582 V+D AL + L Sbjct: 243 TVVDIDALAQAL 254
>SERA_SYNY3 (P73821) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 554 Score = 75.1 bits (183), Expect = 1e-13 Identities = 57/189 (30%), Positives = 86/189 (45%) Frame = +1 Query: 7 VGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 186 VG N+DV AA + GI + N+P T R I +A++ ++ W Sbjct: 100 VGVDNIDVPAATRQGIVVVNSPEGNTIAAAEHALAMMMALARHIPDANKSVKESK---WE 156 Query: 187 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 366 F+G + +T+GV+G G+IGS A + + M L+ +D + S + Sbjct: 157 RKQFIGTEVYKKTLGVVGLGKIGSHVAGVA-KAMGMKLLAYDPFISQERADQIGC----- 210 Query: 367 KANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRG 546 ++ + EAD I+LH T +LIN E LA MK A ++N SRG Sbjct: 211 -----------TLVDLDLLFSEADFITLHIPKTPETANLINAETLAKMKPTARIINCSRG 259 Query: 547 PVIDEVALV 573 +IDE ALV Sbjct: 260 GIIDEEALV 268
>YN14_YEAST (P53839) Putative 2-hydroxyacid dehydrogenase YNL274C (EC 1.-.-.-)| Length = 350 Score = 74.3 bits (181), Expect = 2e-13 Identities = 57/194 (29%), Positives = 89/194 (45%), Gaps = 3/194 (1%) Frame = +1 Query: 10 GYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 189 GY +DV+ K I + N P +++ T R ++ + G + P Sbjct: 92 GYDQIDVEPFKKRHIQVANVPDLVSNATADTHVFLLLGALRNFGIGNRRLIEGNWPEAGP 151 Query: 190 HLF--VGNLLKGQTVGVIGAGRIGSAYA-RMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQ 360 G +G+TVG++G GRIG R+ GF+ N IY + +Q E+ Y Sbjct: 152 ACGSPFGYDPEGKTVGILGLGRIGRCILERLKPFGFE-NFIYHNRHQLPSEEEHGCEYVG 210 Query: 361 FLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNAS 540 F EE L+ +D++S++ L+ T+HLIN E + MK V+VN + Sbjct: 211 F-----------------EEFLKRSDIVSVNVPLNHNTHHLINAETIEKMKDGVVIVNTA 253 Query: 541 RGPVIDEVALVEHL 582 RG VIDE A+ + L Sbjct: 254 RGAVIDEQAMTDAL 267
>Y1556_HAEIN (P45250) Putative 2-hydroxyacid dehydrogenase HI1556 (EC 1.-.-.-)| Length = 315 Score = 73.6 bits (179), Expect = 4e-13 Identities = 58/199 (29%), Positives = 90/199 (45%), Gaps = 6/199 (3%) Frame = +1 Query: 4 AVGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGW 183 A G NVD+ AA + GIA+ N G + T + ++R W Sbjct: 72 ATGTNNVDLVAAEEMGIAVRNVTGYSSTTVPEHVIGLIFSLKHSLAG---WLRDQTEAKW 128 Query: 184 LPHL------FVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFV 345 + ++G T+GV G G +G+ R+ M ++Y + +T + Sbjct: 129 AESKQFCYFDYPITDVRGSTLGVFGKGCLGTEVGRLA-NAVGMKVLYAEHKDATVCREGY 187 Query: 346 TAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAV 525 T + +EVL++AD+++LH L +TT LIN E L+ MKK A Sbjct: 188 TPF--------------------DEVLKQADIVTLHCPLTETTKDLINAETLSKMKKGAF 227 Query: 526 LVNASRGPVIDEVALVEHL 582 L+N RGP+IDE+ALV+ L Sbjct: 228 LINTGRGPLIDELALVDAL 246
>LDHD_LACPE (P26298) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 332 Score = 73.6 bits (179), Expect = 4e-13 Identities = 55/192 (28%), Positives = 88/192 (45%) Frame = +1 Query: 7 VGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 186 VG N+DV G+ I N P R+ ++ + + W Sbjct: 78 VGVDNLDVPTVKARGLNISNVPAYSPNAIAELSVTQLMQLLRQTPMFNKKLAKQDFR-WA 136 Query: 187 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 366 P + L TVGVIG GRIG A A + +GF +I +D+Y++ LEK G ++ Sbjct: 137 PD--IAKELNTMTVGVIGTGRIGRA-AIDIFKGFGAKVIGYDVYRNAELEK----EGMYV 189 Query: 367 KANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRG 546 +++E+ +ADVI+LH K YH++N + + MK A ++N +RG Sbjct: 190 -------------DTLDELYAQADVITLHVPALKDNYHMLNADAFSKMKDGAYILNFARG 236 Query: 547 PVIDEVALVEHL 582 +ID L++ L Sbjct: 237 TLIDSEDLIKAL 248
>SERA_HUMAN (O43175) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 73.6 bits (179), Expect = 4e-13 Identities = 58/191 (30%), Positives = 88/191 (46%) Frame = +1 Query: 10 GYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 189 G NVD++AA + GI + NTP + + R+I +A M+ G W Sbjct: 78 GVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGK---WER 134 Query: 190 HLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLK 369 F+G L G+T+G++G GRIG A M + F M I +D S + Sbjct: 135 KKFMGTELNGKTLGILGLGRIGREVATRM-QSFGMKTIGYDPIISPEVSA---------- 183 Query: 370 ANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGP 549 + G Q + +EE+ D I++H L +T L+N A KK +VN +RG Sbjct: 184 SFGVQQLP------LEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGG 237 Query: 550 VIDEVALVEHL 582 ++DE AL+ L Sbjct: 238 IVDEGALLRAL 248
>SERA_SCHPO (P87228) Putative D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95)| (3-PGDH) Length = 466 Score = 73.2 bits (178), Expect = 5e-13 Identities = 51/190 (26%), Positives = 92/190 (48%) Frame = +1 Query: 7 VGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 186 +G VD+D A + GIA+ N+P + + R++ + + G ++ Sbjct: 128 IGTNQVDLDFAAERGIAVFNSPYANSRSVAELVIGYIISLARQVGDRSLELHRGEWNKVS 187 Query: 187 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 366 + ++G+T+G+IG G IGS + ++ E ++++Y+D+ L Sbjct: 188 SGCWE---IRGKTLGIIGYGHIGSQLS-VLAEAMGLHVVYYDILPIMPLGSA-------- 235 Query: 367 KANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRG 546 K+ SS+ E+L AD +SLH T ++I+ + A MK+ + L+NASRG Sbjct: 236 ----------KQLSSLPELLHRADFVSLHVPASPETKNMISSKEFAAMKEGSYLINASRG 285 Query: 547 PVIDEVALVE 576 V+D ALV+ Sbjct: 286 TVVDIPALVD 295
>SERA_MOUSE (Q61753) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| (A10) Length = 532 Score = 73.2 bits (178), Expect = 5e-13 Identities = 56/191 (29%), Positives = 89/191 (46%) Frame = +1 Query: 10 GYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 189 G NVD++AA + GI + NTP + + R+I +A M+ G +D Sbjct: 78 GVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWDR--- 134 Query: 190 HLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLK 369 F+G L G+T+G++G GRIG A M + F M + +D S + ++G Sbjct: 135 KKFMGTELNGKTLGILGLGRIGREVATRM-QSFGMKTVGYDPIISPEV---AASFGV--- 187 Query: 370 ANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGP 549 + +EE+ D I++H L +T L+N A KK +VN +RG Sbjct: 188 ----------QQLPLEEIWPLCDFITVHTPLLPSTTGLLNDSTFAQCKKGVRVVNCARGG 237 Query: 550 VIDEVALVEHL 582 ++DE AL+ L Sbjct: 238 IVDEGALLRAL 248
>SERA_MACFA (Q60HD7) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 73.2 bits (178), Expect = 5e-13 Identities = 57/191 (29%), Positives = 88/191 (46%) Frame = +1 Query: 10 GYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 189 G NVD++AA + G+ + NTP + + R+I +A M+ G W Sbjct: 78 GVDNVDLEAATRKGVLVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGK---WER 134 Query: 190 HLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLK 369 F+G L G+T+G++G GRIG A M + F M I +D S + Sbjct: 135 KKFMGTELNGKTLGILGLGRIGREVATRM-QSFGMKTIGYDPIISPEVSA---------- 183 Query: 370 ANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGP 549 + G Q + +EE+ D I++H L +T L+N A KK +VN +RG Sbjct: 184 SFGVQQLP------LEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGG 237 Query: 550 VIDEVALVEHL 582 ++DE AL+ L Sbjct: 238 IVDEGALLRAL 248
>LDHD_LACPL (Q88VJ2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH)| Length = 332 Score = 73.2 bits (178), Expect = 5e-13 Identities = 55/192 (28%), Positives = 88/192 (45%) Frame = +1 Query: 7 VGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 186 VG N+DV G+ I N P R+ ++ + + W Sbjct: 78 VGVDNLDVPTVKARGLNISNVPAYSPNAIAELSVTQLMQLLRQTPLFNKKLAKQDFR-WA 136 Query: 187 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 366 P + L TVGVIG GRIG A A + +GF +I +D+Y++ LEK G ++ Sbjct: 137 PD--IAKELNTMTVGVIGTGRIGRA-AIDIFKGFGAKVIGYDVYRNAELEK----EGMYV 189 Query: 367 KANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRG 546 +++E+ +ADVI+LH K YH++N + + MK A ++N +RG Sbjct: 190 -------------DTLDELYAQADVITLHVPALKDNYHMLNADAFSKMKDGAYILNFARG 236 Query: 547 PVIDEVALVEHL 582 +ID L++ L Sbjct: 237 TLIDSEDLIKAL 248
>SERA_RAT (O08651) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 72.8 bits (177), Expect = 7e-13 Identities = 55/191 (28%), Positives = 89/191 (46%) Frame = +1 Query: 10 GYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 189 G NVD++AA + G+ + NTP + + R+I +A M+ G +D Sbjct: 78 GVDNVDLEAATRKGVLVMNTPNGNSLSAAELTCGMLMCLARQIPQATASMKDGKWDR--- 134 Query: 190 HLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLK 369 F+G L G+T+G++G GRIG A M + F M + +D S + ++G Sbjct: 135 KKFMGTELNGKTLGILGLGRIGREVAARM-QAFGMKTVGYDPIISPEV---AASFGV--- 187 Query: 370 ANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGP 549 + +EE+ D I++H L +T L+N A KK +VN +RG Sbjct: 188 ----------QQLPLEEIWPLCDFITVHTPLLPSTTGLLNDSTFAQCKKGVRVVNCARGG 237 Query: 550 VIDEVALVEHL 582 ++DE AL+ L Sbjct: 238 IVDEGALLRAL 248
>LDHD_STRP1 (Q99ZM2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 71.2 bits (173), Expect = 2e-12 Identities = 54/186 (29%), Positives = 86/186 (46%) Frame = +1 Query: 25 DVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLPHLFVG 204 ++D A +N I I N P E+ R + + ++ + LP G Sbjct: 83 NLDLATENDIIITNVPSYSPESIAEFTVTIVLNLIRHVELIRENVKKQNFTWGLP--IRG 140 Query: 205 NLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQ 384 +L TV +IG GRIG A A++ +GF ++ +D+YQS K V Y + Sbjct: 141 RVLGDMTVAIIGTGRIGLATAKIF-KGFGCKVVGYDIYQSDAA-KAVLDYKE-------- 190 Query: 385 PVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEV 564 S+EE +++AD++SLH HL N + KK A+L+N +RG VI+ Sbjct: 191 --------SVEEAIKDADLVSLHMPPTAENTHLFNSDLFKSFKKGAILMNMARGAVIETQ 242 Query: 565 ALVEHL 582 L++ L Sbjct: 243 DLLDAL 248
>LDHD_STRA5 (Q8E0N5) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 71.2 bits (173), Expect = 2e-12 Identities = 51/193 (26%), Positives = 87/193 (45%) Frame = +1 Query: 4 AVGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGW 183 + G +++ A ++GI I N P E+ R++ +R + Sbjct: 76 SAGVDMYNLELAKQHGIIISNVPSYSPESIAEFTVTIALNLIRKVELIRANVREQNFSWT 135 Query: 184 LPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQF 363 LP G +L TV +IG GRIG A A++ +GF +I +D+Y + + + Sbjct: 136 LP--IRGRVLGNMTVAIIGTGRIGLATAKIF-KGFGCRVIGYDIYHNPMADGIL------ 186 Query: 364 LKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASR 543 + +S+EE + EAD++SLH HL N + KK A+L+N +R Sbjct: 187 -----------EYVNSVEEAVEEADLVSLHMPPTAENTHLFNLDMFKQFKKGAILMNMAR 235 Query: 544 GPVIDEVALVEHL 582 G +++ L+E L Sbjct: 236 GALVETKDLLEAL 248
>SERA_BOVIN (Q5EAD2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 70.9 bits (172), Expect = 3e-12 Identities = 56/191 (29%), Positives = 87/191 (45%) Frame = +1 Query: 10 GYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 189 G NVD++AA + GI + NTP + + R+I +A M+ G W Sbjct: 78 GVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQAAASMKDGK---WER 134 Query: 190 HLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLK 369 F+G L G+ +G++G GRIG A M + F M I +D S + Sbjct: 135 KKFMGTELNGKVLGILGLGRIGREVATRM-QSFGMKTIGYDPIISPEVSA---------- 183 Query: 370 ANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGP 549 + G Q + +E++ D I++H L +T L+N A KK +VN +RG Sbjct: 184 SFGVQQLP------LEQIWPLCDFITVHTPLLPSTTGLLNDSTFAQCKKGVCVVNCARGG 237 Query: 550 VIDEVALVEHL 582 ++DE AL+ L Sbjct: 238 IVDEGALLRAL 248
>SERA_PONPY (Q5R7M2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 70.5 bits (171), Expect = 3e-12 Identities = 57/191 (29%), Positives = 87/191 (45%) Frame = +1 Query: 10 GYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 189 G NVD++AA + GI + NTP + + R+I +A M+ G W Sbjct: 78 GVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGK---WER 134 Query: 190 HLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLK 369 F+G L G+T+G++G GRIG A M + M I +D S + Sbjct: 135 KKFMGTELNGKTLGILGLGRIGREVAIRM-QSLGMKTIGYDPIISPEVSA---------- 183 Query: 370 ANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGP 549 + G Q + +EE+ D I++H L +T L+N A KK +VN +RG Sbjct: 184 SFGVQQLP------LEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGG 237 Query: 550 VIDEVALVEHL 582 ++DE AL+ L Sbjct: 238 IVDEGALLRAL 248
>LDHD_STRA3 (Q8E6A9) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 69.7 bits (169), Expect = 6e-12 Identities = 50/193 (25%), Positives = 87/193 (45%) Frame = +1 Query: 4 AVGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGW 183 + G +++ A ++GI I N P E+ R++ +R + Sbjct: 76 SAGVDMYNLELAKQHGIIISNVPSYSPESIAEFTVTIALNLIRKVELIRANVREQNFSWT 135 Query: 184 LPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQF 363 LP G +L TV +IG GRIG A A++ +GF +I +D+Y + + + Sbjct: 136 LP--IRGRVLGNMTVAIIGTGRIGLATAKIF-KGFGCRVIGYDIYHNPMADGIL------ 186 Query: 364 LKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASR 543 + +S+EE + +AD++SLH HL N + KK A+L+N +R Sbjct: 187 -----------EYVNSVEEAVEKADLVSLHMPPTAENTHLFNLDMFKQFKKGAILMNMAR 235 Query: 544 GPVIDEVALVEHL 582 G +++ L+E L Sbjct: 236 GALVETKDLLEAL 248
>DHD2_LACPA (P17584) D-2-hydroxyisocaproate dehydrogenase (EC 1.1.1.-)| (D-HICDH) Length = 333 Score = 69.3 bits (168), Expect = 8e-12 Identities = 54/193 (27%), Positives = 89/193 (46%), Gaps = 1/193 (0%) Frame = +1 Query: 7 VGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 186 VG N+D+ A + GI + N P R + + ++AG Y+ Sbjct: 77 VGTDNIDMTAMKQYGIRLSNVPAYSPAAIAEFALTDTLYLLRNMGKVQAQLQAGDYEK-- 134 Query: 187 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 366 F+G L QTVGV+G G IG A + +GF +I +D Y Sbjct: 135 AGTFIGKELGQQTVGVMGTGHIGQV-AIKLFKGFGAKVIAYDPYPM-------------- 179 Query: 367 KANGEQPVTWKRASSMEEVLREADVISLH-PVLDKTTYHLINPERLAMMKKEAVLVNASR 543 G+ P S+E++ +++DVI LH P +++ T H+IN +MK A+++N +R Sbjct: 180 --KGDHPDF--DYVSLEDLFKQSDVIDLHVPGIEQNT-HIINEAAFNLMKPGAIVINTAR 234 Query: 544 GPVIDEVALVEHL 582 +ID A++ +L Sbjct: 235 PNLIDTQAMLSNL 247
>LDHD_LEUMC (P51011) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 331 Score = 69.3 bits (168), Expect = 8e-12 Identities = 57/193 (29%), Positives = 89/193 (46%), Gaps = 1/193 (0%) Frame = +1 Query: 7 VGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEAD-QFMRAGLYDGW 183 VG N+D DAA + I N P RR D + + L W Sbjct: 78 VGTDNIDFDAAREFNFNISNVPVYSPNAIAEHSMLQLSRLLRRTKALDAKIAKRDLR--W 135 Query: 184 LPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQF 363 P G ++ QTVGVIG G IG A +++GF +I +D Y + L+ A G + Sbjct: 136 APT--TGREMRMQTVGVIGTGHIGRV-AINILKGFGAKVIAYDKYPNAELQ----AEGLY 188 Query: 364 LKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASR 543 + +++E+ +AD ISL+ +HLIN + +A MK V++NA+R Sbjct: 189 V-------------DTLDELYAQADAISLYVPGVPENHHLINADAIAKMKDGVVIMNAAR 235 Query: 544 GPVIDEVALVEHL 582 G ++D A+++ L Sbjct: 236 GNLMDIDAIIDGL 248
>FDH_NEUCR (Q07103) Formate dehydrogenase (EC 1.2.1.2) (NAD-dependent formate| dehydrogenase) (FDH) Length = 375 Score = 69.3 bits (168), Expect = 8e-12 Identities = 54/195 (27%), Positives = 90/195 (46%), Gaps = 3/195 (1%) Frame = +1 Query: 7 VGYXNVDVDAANKN--GIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDG 180 +G +VD++AANK GI + G + R V A + ++ G +D Sbjct: 94 IGSDHVDLNAANKTNGGITVAEVTGSNVVSVAEHVLMTILVLVRNFVPAHEQIQEGRWD- 152 Query: 181 WLPHLFVGNL-LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYG 357 + L+G+ VG +G GRIG R + L+Y+D YQ EK Sbjct: 153 -VAEAAKNEFDLEGKVVGTVGVGRIGERVLRRLKPFDCKELLYYD-YQPLSAEK------ 204 Query: 358 QFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 537 E + +R + +EE+L + DV++++ L + T L N E ++ MKK + LVN Sbjct: 205 -------EAEIGCRRVADLEEMLAQCDVVTINCPLHEKTQGLFNKELISKMKKGSWLVNT 257 Query: 538 SRGPVIDEVALVEHL 582 +RG ++ + + E L Sbjct: 258 ARGAIVVKEDVAEAL 272
>SERA_YEAST (P40054) D-3-phosphoglycerate dehydrogenase 1 (EC 1.1.1.95) (3-PGDH| 1) Length = 469 Score = 69.3 bits (168), Expect = 8e-12 Identities = 46/190 (24%), Positives = 94/190 (49%) Frame = +1 Query: 7 VGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 186 +G VD+D A GIA+ N+P + + R++ + + G ++ Sbjct: 131 IGTNQVDLDYATSRGIAVFNSPFSNSRSVAELVIAEIISLARQLGDRSIELHTGTWNKVA 190 Query: 187 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 366 + ++G+T+G+IG G IGS + ++ E ++++Y+D+ + A G Sbjct: 191 ARCWE---VRGKTLGIIGYGHIGSQLS-VLAEAMGLHVLYYDIVT-------IMALG--- 236 Query: 367 KANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRG 546 T ++ S+++E+L ++D ++LH T +++ + A MK A ++NASRG Sbjct: 237 --------TARQVSTLDELLNKSDFVTLHVPATPETEKMLSAPQFAAMKDGAYVINASRG 288 Query: 547 PVIDEVALVE 576 V+D +L++ Sbjct: 289 TVVDIPSLIQ 298
>PDXB_VIBVU (Q8DB36) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 377 Score = 68.9 bits (167), Expect = 1e-11 Identities = 42/125 (33%), Positives = 71/125 (56%), Gaps = 4/125 (3%) Frame = +1 Query: 220 QTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWK 399 QTVG+IGAG++GS Y + ++G + ++ D F + G++ + Sbjct: 118 QTVGIIGAGQVGS-YLQQCLQGIGIKVLIND---------------PFKQEEGDE----R 157 Query: 400 RASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVA 567 +S++ +L+EADVI+LH + + T+HLIN E L ++ + +L+NA+RGPV+D A Sbjct: 158 EFTSLDRLLQEADVITLHTPITRDGKYPTHHLINEEILNSLRADQILINAARGPVVDNQA 217 Query: 568 LVEHL 582 L L Sbjct: 218 LKRRL 222
>PDXB_VIBVY (Q7MIT6) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 377 Score = 68.6 bits (166), Expect = 1e-11 Identities = 41/125 (32%), Positives = 71/125 (56%), Gaps = 4/125 (3%) Frame = +1 Query: 220 QTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWK 399 QTVG++GAG++GS Y + ++G + ++ D F + G++ + Sbjct: 118 QTVGIVGAGQVGS-YLQQCLQGIGIKVLIND---------------PFKQEEGDE----R 157 Query: 400 RASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVA 567 +S++ +L+EADVI+LH + + T+HLIN E L ++ + +L+NA+RGPV+D A Sbjct: 158 EFTSLDRLLQEADVITLHTPITRDGKYPTHHLINKEILNSLRADQILINAARGPVVDNQA 217 Query: 568 LVEHL 582 L L Sbjct: 218 LKHRL 222
>YEAA_SCHPO (O14075) Putative 2-hydroxyacid dehydrogenase UNK4.10 (EC 1.-.-.-)| Length = 334 Score = 67.8 bits (164), Expect = 2e-11 Identities = 52/198 (26%), Positives = 88/198 (44%), Gaps = 4/198 (2%) Frame = +1 Query: 1 MAVGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYD- 177 + GY VDV A GI + + P + + T R + G+++ Sbjct: 87 LGAGYETVDVAACTARGIQVSHVPKAVDDATADVGIFLMLGALRGFNQ-------GIFEL 139 Query: 178 ---GWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVT 348 W + + +G+T+G++G G IG A+ F M ++Y + T L + Sbjct: 140 HKNNWNANCKPSHDPEGKTLGILGLGGIGKTMAKRA-RAFDMKIVY---HNRTPLPEEEA 195 Query: 349 AYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVL 528 +F+ S +++L ++DV+SL+ L+ T H+I MK+ V+ Sbjct: 196 EGAEFV--------------SFDDLLAKSDVLSLNLPLNAHTRHIIGKPEFQKMKRGIVI 241 Query: 529 VNASRGPVIDEVALVEHL 582 VN +RG V+DE ALVE L Sbjct: 242 VNTARGAVMDEAALVEAL 259
>SERA_SHIFL (P0A9T3) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 409 Score = 67.0 bits (162), Expect = 4e-11 Identities = 50/192 (26%), Positives = 89/192 (46%) Frame = +1 Query: 7 VGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 186 +G VD+DAA K GI + N P T + R + EA+ G+++ Sbjct: 83 IGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLA 142 Query: 187 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 366 F +G+ +G+IG G IG+ ++ E M + ++D+ L Sbjct: 143 AGSFEA---RGKKLGIIGYGHIGTQLG-ILAESLGMYVYFYDIENKLPL----------- 187 Query: 367 KANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRG 546 N Q + ++L +DV+SLH + +T +++ + +++MK ++L+NASRG Sbjct: 188 -GNATQ------VQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRG 240 Query: 547 PVIDEVALVEHL 582 V+D AL + L Sbjct: 241 TVVDIPALCDAL 252
>SERA_ECOLI (P0A9T0) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 409 Score = 67.0 bits (162), Expect = 4e-11 Identities = 50/192 (26%), Positives = 89/192 (46%) Frame = +1 Query: 7 VGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 186 +G VD+DAA K GI + N P T + R + EA+ G+++ Sbjct: 83 IGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLA 142 Query: 187 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 366 F +G+ +G+IG G IG+ ++ E M + ++D+ L Sbjct: 143 AGSFEA---RGKKLGIIGYGHIGTQLG-ILAESLGMYVYFYDIENKLPL----------- 187 Query: 367 KANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRG 546 N Q + ++L +DV+SLH + +T +++ + +++MK ++L+NASRG Sbjct: 188 -GNATQ------VQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRG 240 Query: 547 PVIDEVALVEHL 582 V+D AL + L Sbjct: 241 TVVDIPALCDAL 252
>SERA_ECOL6 (P0A9T1) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 409 Score = 67.0 bits (162), Expect = 4e-11 Identities = 50/192 (26%), Positives = 89/192 (46%) Frame = +1 Query: 7 VGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 186 +G VD+DAA K GI + N P T + R + EA+ G+++ Sbjct: 83 IGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLA 142 Query: 187 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 366 F +G+ +G+IG G IG+ ++ E M + ++D+ L Sbjct: 143 AGSFEA---RGKKLGIIGYGHIGTQLG-ILAESLGMYVYFYDIENKLPL----------- 187 Query: 367 KANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRG 546 N Q + ++L +DV+SLH + +T +++ + +++MK ++L+NASRG Sbjct: 188 -GNATQ------VQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRG 240 Query: 547 PVIDEVALVEHL 582 V+D AL + L Sbjct: 241 TVVDIPALCDAL 252
>SERA_ECO57 (P0A9T2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 409 Score = 67.0 bits (162), Expect = 4e-11 Identities = 50/192 (26%), Positives = 89/192 (46%) Frame = +1 Query: 7 VGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 186 +G VD+DAA K GI + N P T + R + EA+ G+++ Sbjct: 83 IGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLA 142 Query: 187 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 366 F +G+ +G+IG G IG+ ++ E M + ++D+ L Sbjct: 143 AGSFEA---RGKKLGIIGYGHIGTQLG-ILAESLGMYVYFYDIENKLPL----------- 187 Query: 367 KANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRG 546 N Q + ++L +DV+SLH + +T +++ + +++MK ++L+NASRG Sbjct: 188 -GNATQ------VQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRG 240 Query: 547 PVIDEVALVEHL 582 V+D AL + L Sbjct: 241 TVVDIPALCDAL 252
>SER33_YEAST (P40510) D-3-phosphoglycerate dehydrogenase 2 (EC 1.1.1.95) (3-PGDH| 2) Length = 469 Score = 65.5 bits (158), Expect = 1e-10 Identities = 45/190 (23%), Positives = 93/190 (48%) Frame = +1 Query: 7 VGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 186 +G VD+ A GIA+ N+P + + R++ + + G ++ Sbjct: 131 IGTNQVDLKYAASKGIAVFNSPFSNSRSVAELVIGEIISLARQLGDRSIELHTGTWNKVA 190 Query: 187 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 366 + ++G+T+G+IG G IGS + ++ E ++++Y+D+ + A G Sbjct: 191 ARCWE---VRGKTLGIIGYGHIGSQLS-VLAEAMGLHVLYYDIVT-------IMALG--- 236 Query: 367 KANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRG 546 T ++ S+++E+L ++D ++LH T +++ + A MK A ++NASRG Sbjct: 237 --------TARQVSTLDELLNKSDFVTLHVPATPETEKMLSAPQFAAMKDGAYVINASRG 288 Query: 547 PVIDEVALVE 576 V+D +L++ Sbjct: 289 TVVDIPSLIQ 298
>DHGY_METEX (Q59516) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-dependent| hydroxypyruvate reductase) (HPR) (GDH) (Hydroxypyruvate dehydrogenase) (Glyoxylate reductase) (HPR-A) Length = 313 Score = 64.3 bits (155), Expect = 2e-10 Identities = 52/196 (26%), Positives = 83/196 (42%), Gaps = 3/196 (1%) Frame = +1 Query: 4 AVGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGW 183 A G VD AA GI + N T R IV +R G ++ Sbjct: 72 ATGTDVVDKAAAKAQGITVVNIRNYAFNTVPEHVVGLMFALRRAIVPYANSVRRGDWNKS 131 Query: 184 LPHLFVGNLL---KGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAY 354 + + G T+G+IG G +G + A+ E M ++ FD++ L Sbjct: 132 KQFCYFDYPIYDIAGSTLGIIGYGALGKSIAKRA-EALGMKVLAFDVFPQDGLV------ 184 Query: 355 GQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVN 534 +E +L ++DVI+LH L T ++I E+L MK+ A+L+N Sbjct: 185 ------------------DLETILTQSDVITLHVPLTPDTKNMIGAEQLKKMKRSAILIN 226 Query: 535 ASRGPVIDEVALVEHL 582 +RG ++DE AL++ L Sbjct: 227 TARGGLVDEAALLQAL 242
>VANH_ENTFA (Q47748) D-specific alpha-keto acid dehydrogenase (EC 1.1.1.-)| (Vancomycin B-type resistance protein vanHB) Length = 323 Score = 62.4 bits (150), Expect = 9e-10 Identities = 50/193 (25%), Positives = 82/193 (42%) Frame = +1 Query: 4 AVGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGW 183 ++G ++D AA + GI++G + + I A + A + Sbjct: 80 SIGCNHIDTTAAERMGISVGT----VAYSPDSVADYALMLMLMAIRGAKSTIHAVAQQNF 135 Query: 184 LPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQF 363 G L+ TVGVIG G IG A + + GF ++ +D K Y Q Sbjct: 136 RLDCVRGKELRDMTVGVIGTGHIGQAVVKRL-RGFGCRVLAYD-----NSRKIEADYVQ- 188 Query: 364 LKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASR 543 ++E+L+ +D+++LH L T HLI ++ MK+ A L+N R Sbjct: 189 ----------------LDELLKNSDIVTLHVPLCADTRHLIGQRQIGEMKQGAFLINTGR 232 Query: 544 GPVIDEVALVEHL 582 G ++D +LVE L Sbjct: 233 GALVDTGSLVEAL 245
>FDH1_ORYSA (Q9SXP2) Formate dehydrogenase 1, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase 1) (FDH 1) Length = 376 Score = 62.4 bits (150), Expect = 9e-10 Identities = 51/191 (26%), Positives = 87/191 (45%), Gaps = 1/191 (0%) Frame = +1 Query: 7 VGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 186 +G ++D+ AA G+ + G T + R + Q + G ++ Sbjct: 120 IGSDHIDLPAAAAAGLTVAEVTGSNTVSVAEDELMRILILLRNFLPGYQQVVHGEWNV-A 178 Query: 187 PHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFD-LYQSTRLEKFVTAYGQF 363 + L+G+TVG +GAGRIG + + + F NL+Y D L LEK + A Sbjct: 179 GIAYRAYDLEGKTVGTVGAGRIGRLLLQRL-KPFNCNLLYHDRLKIDPELEKEIGA---- 233 Query: 364 LKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASR 543 K ++ +L + DVI ++ L + T + N ER+A MKK ++VN +R Sbjct: 234 -----------KYEEDLDAMLPKCDVIVINTPLTEKTRGMFNKERIAKMKKGVIIVNNAR 282 Query: 544 GPVIDEVALVE 576 G ++D A+ + Sbjct: 283 GAIMDTQAVAD 293
>FDH_HORVU (Q9ZRI8) Formate dehydrogenase, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase) (FDH) Length = 377 Score = 62.0 bits (149), Expect = 1e-09 Identities = 49/192 (25%), Positives = 88/192 (45%), Gaps = 2/192 (1%) Frame = +1 Query: 7 VGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYD-GW 183 +G ++D+ AA G+ + G T + R + Q + G ++ Sbjct: 121 IGSDHIDLPAAAAAGLTVARVTGSNTVSVAEDELMRILILLRNFLPGYQQVVKGEWNVAG 180 Query: 184 LPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQ-STRLEKFVTAYGQ 360 + H L+G+TVG +GAGR G + + + F NL+Y D Q + LEK + A Sbjct: 181 IAHRAYD--LEGKTVGTVGAGRYGRLLLQRL-KPFNCNLLYHDRLQINPELEKEIGA--- 234 Query: 361 FLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNAS 540 K ++ +L + DV+ ++ L + T + N E++A MKK ++VN + Sbjct: 235 ------------KFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNA 282 Query: 541 RGPVIDEVALVE 576 RG ++D A+ + Sbjct: 283 RGAIMDTQAVAD 294
>PDXB_VIBCH (Q9KQ92) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 381 Score = 61.6 bits (148), Expect = 2e-09 Identities = 39/125 (31%), Positives = 68/125 (54%), Gaps = 4/125 (3%) Frame = +1 Query: 220 QTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWK 399 +TVG+IGAG++GS Y + G M ++ D + +A G++ + Sbjct: 118 KTVGIIGAGQVGS-YLAKCLSGIGMKVLLNDPPK---------------QAQGDE----R 157 Query: 400 RASSMEEVLREADVISLHPVLDK----TTYHLINPERLAMMKKEAVLVNASRGPVIDEVA 567 + +E +L++ADVI+LH + + T+HLI+ L ++ + +L+NA+RGPV+D A Sbjct: 158 EFTELETLLKQADVITLHTPITRGGEWPTHHLIDAAILEQLRSDQILINAARGPVVDNAA 217 Query: 568 LVEHL 582 L L Sbjct: 218 LKARL 222
>FDH_SOLTU (Q07511) Formate dehydrogenase, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase) (FDH) Length = 381 Score = 60.5 bits (145), Expect = 3e-09 Identities = 48/192 (25%), Positives = 89/192 (46%), Gaps = 2/192 (1%) Frame = +1 Query: 7 VGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYD-GW 183 +G +VD+ AA G+ + G T + R + + G ++ Sbjct: 125 IGSDHVDLKAAAAAGLTVAEVTGSNTVSVAEDELMRILILVRNFLPGHHQVINGEWNVAA 184 Query: 184 LPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFD-LYQSTRLEKFVTAYGQ 360 + H L+G+TVG +GAGRIG + + + F NL+Y D L + LE + A Sbjct: 185 IAHRAYD--LEGKTVGTVGAGRIGRLLLQRL-KPFNCNLLYHDRLKMDSELENQIGA--- 238 Query: 361 FLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNAS 540 K ++++L + D++ ++ L + T + + ER+A +KK ++VN + Sbjct: 239 ------------KFEEDLDKMLSKCDIVVINTPLTEKTKGMFDKERIAKLKKGVLIVNNA 286 Query: 541 RGPVIDEVALVE 576 RG ++D A+V+ Sbjct: 287 RGAIMDTQAVVD 298
>FDH2_ORYSA (Q67U69) Formate dehydrogenase 2, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase 2) (FDH 2) Length = 378 Score = 60.1 bits (144), Expect = 5e-09 Identities = 50/192 (26%), Positives = 86/192 (44%), Gaps = 2/192 (1%) Frame = +1 Query: 7 VGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYD-GW 183 VG ++D+ AA G+ + G T + R + + G ++ Sbjct: 122 VGSDHIDLPAAAAAGLTVAEITGSNTVSVAEDQLMRILLLLRNFLPGHHQIVNGEWNVAG 181 Query: 184 LPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQ-STRLEKFVTAYGQ 360 + H L+G+TVG +GAGRIG + + + F NL+Y D + LEK + A Sbjct: 182 IAHRTYD--LEGKTVGTVGAGRIGRLLLQRL-KPFNCNLMYHDRVKIDPELEKEIGA--- 235 Query: 361 FLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNAS 540 K ++ +L + DV+ ++ L + T + N ER+A MKK +VN + Sbjct: 236 ------------KYEEDLDAMLPKCDVVVINMPLTEKTRGMFNKERIAKMKKGVTIVNNA 283 Query: 541 RGPVIDEVALVE 576 RG ++D A+ + Sbjct: 284 RGAIMDTQAVAD 295
>VANH_ENTFC (Q05709) D-specific alpha-keto acid dehydrogenase (EC 1.1.1.-)| (Vancomycin resistance protein vanH) Length = 322 Score = 60.1 bits (144), Expect = 5e-09 Identities = 37/127 (29%), Positives = 65/127 (51%) Frame = +1 Query: 202 GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGE 381 G +L TVGV+G G+IG A + GF ++ + +S + Y F Sbjct: 141 GKVLSDMTVGVVGTGQIGKAVIERL-RGFGCKVLAYSRSRSIEVN-----YVPF------ 188 Query: 382 QPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDE 561 +E+L+ +D+++LH L+ T+++I+ E++ MK+ A L+N RGP++D Sbjct: 189 -----------DELLQNSDIVTLHVPLNTDTHYIISHEQIQRMKQGAFLINTGRGPLVDT 237 Query: 562 VALVEHL 582 LV+ L Sbjct: 238 YELVKAL 244
>PDXB_PSEPK (Q88L20) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 380 Score = 59.7 bits (143), Expect = 6e-09 Identities = 46/132 (34%), Positives = 67/132 (50%), Gaps = 5/132 (3%) Frame = +1 Query: 202 GNLLKGQTVGVIGAGRIGSAYARMMIE-GFKMNLIYFDLYQSTRLEKFVTAYGQFLKANG 378 G L + GV+GAG +G R++ G+K+ L+ L Q+ +V Sbjct: 111 GVALPERVYGVVGAGEVGGRLVRVLHGLGWKV-LVCDPLRQAAEGGDYV----------- 158 Query: 379 EQPVTWKRASSMEEVLREADVISLHPVLDK----TTYHLINPERLAMMKKEAVLVNASRG 546 S+E +L++ DVISLH L + T+HL+ +LA ++ A LVNASRG Sbjct: 159 ----------SLETILQQCDVISLHTPLQRGGQHPTWHLLGQAQLAQLRPGAWLVNASRG 208 Query: 547 PVIDEVALVEHL 582 PV+D VAL E L Sbjct: 209 PVVDNVALRELL 220
>PDXB_SHEON (Q8ECR2) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 376 Score = 59.7 bits (143), Expect = 6e-09 Identities = 42/126 (33%), Positives = 66/126 (52%), Gaps = 4/126 (3%) Frame = +1 Query: 211 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 390 L+G+ VG++GAG GSA A+ + E F + ++ D + +A G+ Sbjct: 115 LRGKVVGIVGAGNTGSATAKCL-EAFGIKVLLNDPIK---------------EAEGDP-- 156 Query: 391 TWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVID 558 + S+E +L+EAD+ISLH + +T T HL + RL +K L+N RG VID Sbjct: 157 --RDFVSLETLLQEADIISLHVPITRTGEHKTLHLFDEARLMSLKANIWLINCCRGDVID 214 Query: 559 EVALVE 576 AL++ Sbjct: 215 NQALIK 220
>PDXB_VIBPA (Q87MN8) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 377 Score = 58.9 bits (141), Expect = 1e-08 Identities = 37/125 (29%), Positives = 69/125 (55%), Gaps = 4/125 (3%) Frame = +1 Query: 220 QTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWK 399 +TVG+IGAG++GS Y ++G +N++ D + K P ++ Sbjct: 118 KTVGIIGAGQVGS-YLEKCLKGMGINVLINDPF----------------KQEAGDPRSF- 159 Query: 400 RASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVA 567 + + E++ ++D+I+LH + K T+HLI+ + L ++ + +L+NA+RGPV+D A Sbjct: 160 --TPLAELIEQSDIITLHTPITKDGLHPTHHLIDEKVLNGLRGDQILINAARGPVVDNQA 217 Query: 568 LVEHL 582 L + L Sbjct: 218 LKQRL 222
>PDXB_PHOLL (Q7N2B2) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 375 Score = 58.5 bits (140), Expect = 1e-08 Identities = 40/129 (31%), Positives = 69/129 (53%), Gaps = 5/129 (3%) Frame = +1 Query: 211 LKGQTVGVIGAGRIGSAYA-RMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQP 387 LK + VG++G G +GS A R+ + G + L R ++ G+ Sbjct: 114 LKDKVVGIVGVGNVGSRLAERLAVLGIRTLLC-----DPPRADR------------GDAG 156 Query: 388 VTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVI 555 W S+E++++EAD+++ H L+K+ T+HL++ E L+++ +L+NASRG VI Sbjct: 157 EFW----SLEKLVKEADILTFHTPLNKSGPYKTHHLVDVELLSVLPDNRILINASRGEVI 212 Query: 556 DEVALVEHL 582 D AL+ L Sbjct: 213 DNQALLTAL 221
>PDXB_PSESM (Q884R9) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 380 Score = 58.2 bits (139), Expect = 2e-08 Identities = 44/125 (35%), Positives = 66/125 (52%), Gaps = 5/125 (4%) Frame = +1 Query: 211 LKGQTVGVIGAGRIGSAY-ARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQP 387 L+ +T GV+GAG++G A + G+K+ L+ QS FV Sbjct: 114 LRQRTYGVVGAGQVGGRLIAVLKALGWKV-LVCDPPRQSAEGGDFV-------------- 158 Query: 388 VTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVI 555 S++E+L+ DVISLH LDK+ T+HL++ RL +++ A L+NASRG V+ Sbjct: 159 -------SLDEILQRCDVISLHTPLDKSGQSPTWHLLDEARLRQLRQGAWLINASRGAVV 211 Query: 556 DEVAL 570 D AL Sbjct: 212 DNRAL 216
>FDH_ARATH (Q9S7E4) Formate dehydrogenase, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase) (FDH) Length = 384 Score = 57.4 bits (137), Expect = 3e-08 Identities = 38/123 (30%), Positives = 64/123 (52%), Gaps = 1/123 (0%) Frame = +1 Query: 211 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFD-LYQSTRLEKFVTAYGQFLKANGEQP 387 L+G+T+G +GAGRIG + + + F NL+Y D L + LEK A Sbjct: 195 LEGKTIGTVGAGRIGKLLLQRL-KPFGCNLLYHDRLQMAPELEKETGA------------ 241 Query: 388 VTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVA 567 K + E+L + DVI ++ L + T + N E + +KK ++VN +RG +++ A Sbjct: 242 ---KFVEDLNEMLPKCDVIVINMPLTEKTRGMFNKELIGKLKKGVLIVNNARGAIMERQA 298 Query: 568 LVE 576 +V+ Sbjct: 299 VVD 301
>FDH_PICAN (P33677) Formate dehydrogenase (EC 1.2.1.2) (NAD-dependent formate| dehydrogenase) (FDH) Length = 361 Score = 57.0 bits (136), Expect = 4e-08 Identities = 48/186 (25%), Positives = 84/186 (45%), Gaps = 4/186 (2%) Frame = +1 Query: 7 VGYXNVDVDAANKNG--IAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDG 180 VG ++D+D N++G I++ G + R V A + + +G G Sbjct: 92 VGSDHIDLDYINQSGRDISVLEVTGSNVVSVAEHVVMTMLVLVRNFVPAHEQIISG---G 148 Query: 181 WLPHLFVGNL--LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAY 354 W + ++G+ + IGAGRIG ++ L+Y+D YQS Sbjct: 149 WNVAEIAKDSFDIEGKVIATIGAGRIGYRVLERLVAFNPKELLYYD-YQS---------- 197 Query: 355 GQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVN 534 L E+ V +R ++E++ +AD+++++ L + L+N E L KK A LVN Sbjct: 198 ---LSKEAEEKVGARRVHDIKELVAQADIVTINCPLHAGSKGLVNAELLKHFKKGAWLVN 254 Query: 535 ASRGPV 552 +RG + Sbjct: 255 TARGAI 260
>FDH_EMENI (Q03134) Probable formate dehydrogenase (EC 1.2.1.2) (NAD-dependent| formate dehydrogenase) (FDH) Length = 377 Score = 57.0 bits (136), Expect = 4e-08 Identities = 56/213 (26%), Positives = 88/213 (41%), Gaps = 21/213 (9%) Frame = +1 Query: 7 VGYXNVDVDAANKN--GIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDG 180 +G +VD+DAANK GI + G + R V A +R G Sbjct: 89 IGSDHVDLDAANKTNGGITVAEVTGSNVVSVAEHVVMTILLLVRNFVPAHDQIRNG---D 145 Query: 181 WLPHLFVGNL--LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAY 354 W N L+ + VG +G GRIG R + L+Y+D YQ R E Sbjct: 146 WNVAAVAKNEFDLENKVVGTVGVGRIGERVLRRLKPFDCKELLYYD-YQPLRPEV----- 199 Query: 355 GQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMK------- 513 E+ + +R S+EE++ + DV++++ L + T L N E ++ MK Sbjct: 200 --------EKEIGARRVDSLEEMVSQCDVVTINCPLHEKTRGLFNKELISKMKPGKSALL 251 Query: 514 ----------KEAVLVNASRGPVIDEVALVEHL 582 K + LVN +RG ++ + + E L Sbjct: 252 YLIIPMLMYHKGSWLVNTARGAIVVKEDVAEAL 284
>PDXB_PSEAE (Q9I3W9) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 380 Score = 55.1 bits (131), Expect = 1e-07 Identities = 42/124 (33%), Positives = 62/124 (50%), Gaps = 4/124 (3%) Frame = +1 Query: 211 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 390 L +T GV+GAG++G ++ G ++ D + R G+F+ Sbjct: 114 LAERTYGVVGAGQVGGRLVEVL-RGLGWKVLVCDPPRQAREPD-----GEFV-------- 159 Query: 391 TWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVID 558 S+E +L EADVISLH L++ T HL++ RLA ++ LVNASRG V+D Sbjct: 160 ------SLERLLAEADVISLHTPLNRDGEHPTRHLLDEPRLAALRPGTWLVNASRGAVVD 213 Query: 559 EVAL 570 AL Sbjct: 214 NQAL 217
>PDXB_YERPS (Q668W7) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 375 Score = 55.1 bits (131), Expect = 1e-07 Identities = 41/132 (31%), Positives = 65/132 (49%), Gaps = 5/132 (3%) Frame = +1 Query: 202 GNLLKGQTVGVIGAGRIGSAY-ARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANG 378 G L+ +TVG+IG G +GS AR+ G + L R ++ G Sbjct: 111 GFQLRDKTVGIIGVGNVGSRLNARLQALGVRTLLC-----DPPRADR------------G 153 Query: 379 EQPVTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRG 546 + W +E+++READV++ H L+KT + H+ + E LA + +L+NA RG Sbjct: 154 DNEAFWP----LEKLVREADVLTFHTPLNKTGAYQSLHMADDELLAALPDGRILINACRG 209 Query: 547 PVIDEVALVEHL 582 V+D AL+ L Sbjct: 210 AVVDNAALLRAL 221
>PDXB_YERPE (Q8D0U3) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 375 Score = 55.1 bits (131), Expect = 1e-07 Identities = 41/132 (31%), Positives = 65/132 (49%), Gaps = 5/132 (3%) Frame = +1 Query: 202 GNLLKGQTVGVIGAGRIGSAY-ARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANG 378 G L+ +TVG+IG G +GS AR+ G + L R ++ G Sbjct: 111 GFQLRDKTVGIIGVGNVGSRLNARLQALGVRTLLC-----DPPRADR------------G 153 Query: 379 EQPVTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRG 546 + W +E+++READV++ H L+KT + H+ + E LA + +L+NA RG Sbjct: 154 DNEAFWP----LEKLVREADVLTFHTPLNKTGAYQSLHMADDELLAALPDGRILINACRG 209 Query: 547 PVIDEVALVEHL 582 V+D AL+ L Sbjct: 210 AVVDNAALLRAL 221
>PDXB_SALTY (P60802) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 54.3 bits (129), Expect = 3e-07 Identities = 37/131 (28%), Positives = 66/131 (50%), Gaps = 4/131 (3%) Frame = +1 Query: 202 GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGE 381 G L+ +T+G++G G +GS + +E + + D ++ R ++ G F Sbjct: 111 GFSLRDRTIGIVGVGNVGSRL-QTRLEALGIRTLLCDPPRAARGDE-----GDF------ 158 Query: 382 QPVTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGP 549 +++E+++EADV++ H L K T HL + + +K A+L+NA RGP Sbjct: 159 --------RTLDELVQEADVLTFHTPLYKDGPYKTLHLADETLIRRLKPGAILINACRGP 210 Query: 550 VIDEVALVEHL 582 V+D AL+ L Sbjct: 211 VVDNAALLARL 221
>PDXB_SALTI (P60801) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 54.3 bits (129), Expect = 3e-07 Identities = 37/131 (28%), Positives = 66/131 (50%), Gaps = 4/131 (3%) Frame = +1 Query: 202 GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGE 381 G L+ +T+G++G G +GS + +E + + D ++ R ++ G F Sbjct: 111 GFSLRDRTIGIVGVGNVGSRL-QTRLEALGIRTLLCDPPRAARGDE-----GDF------ 158 Query: 382 QPVTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGP 549 +++E+++EADV++ H L K T HL + + +K A+L+NA RGP Sbjct: 159 --------RTLDELVQEADVLTFHTPLYKDGPYKTLHLADETLIRRLKPGAILINACRGP 210 Query: 550 VIDEVALVEHL 582 V+D AL+ L Sbjct: 211 VVDNAALLARL 221
>PDXB_SHESP (Q56731) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| (Fragment) Length = 274 Score = 53.9 bits (128), Expect = 3e-07 Identities = 39/126 (30%), Positives = 62/126 (49%), Gaps = 4/126 (3%) Frame = +1 Query: 211 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 390 LK +TVG++GAG GSA A+ + L++ + Q + F+ Sbjct: 2 LKDKTVGIVGAGNTGSAVAKCLQAYGVTVLLHDPVIQDSDPRDFI--------------- 46 Query: 391 TWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVID 558 S++E++ DVISLH + KT T++L + RL +K+ L+N RG VID Sbjct: 47 ------SLDELIACCDVISLHVPITKTGEHKTWYLFDEARLNSLKQGTWLLNCCRGEVID 100 Query: 559 EVALVE 576 AL++ Sbjct: 101 NQALIK 106
>PDXB_SHEVI (Q56733) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| (Fragment) Length = 274 Score = 53.5 bits (127), Expect = 4e-07 Identities = 39/126 (30%), Positives = 61/126 (48%), Gaps = 4/126 (3%) Frame = +1 Query: 211 LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPV 390 LK +TVG++GAG GSA A+ + L++ + Q + F+ Sbjct: 2 LKDKTVGIVGAGNTGSAVAKCLQAYGVTVLLHDPVIQDSDPRDFI--------------- 46 Query: 391 TWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVID 558 S++E++ DVISLH + KT T++L + RL +K L+N RG VID Sbjct: 47 ------SLDELIARCDVISLHVPIIKTGEHKTWYLFDETRLNSLKPGTWLLNCCRGEVID 100 Query: 559 EVALVE 576 AL++ Sbjct: 101 NRALIK 106
>PDXB_PHOPR (Q6LNU2) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 391 Score = 53.1 bits (126), Expect = 6e-07 Identities = 36/125 (28%), Positives = 62/125 (49%), Gaps = 4/125 (3%) Frame = +1 Query: 220 QTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWK 399 +T+G+IGAG +GS Y ++ + + D + EQ + Sbjct: 118 KTIGIIGAGNVGS-YLAQCLDALGIPYLLNDPIK-------------------EQEGDTR 157 Query: 400 RASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVA 567 + S+E + + DVI++H + K T+HLIN + ++ +A+L+NA+RGPV D A Sbjct: 158 QFHSLEAIKAQCDVITVHTPITKDGEYPTHHLINEAFIDALQPDAILINAARGPVTDNQA 217 Query: 568 LVEHL 582 L + L Sbjct: 218 LKKAL 222
>FDH_PSESR (P33160) Formate dehydrogenase (EC 1.2.1.2) (NAD-dependent formate| dehydrogenase) (FDH) Length = 400 Score = 52.4 bits (124), Expect = 1e-06 Identities = 50/194 (25%), Positives = 85/194 (43%), Gaps = 2/194 (1%) Frame = +1 Query: 7 VGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWL 186 +G +VD+ +A + + + + R + + ++ R G GW Sbjct: 122 IGSDHVDLQSAIDRNVTVAEVTYCNSISVAEHVVMMILSLVRNYLPSHEWARKG---GWN 178 Query: 187 PHLFVGNL--LKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQ 360 V + L+ VG + AGRIG A R + F ++L Y D + RL + V Sbjct: 179 IADCVSHAYDLEAMHVGTVAAGRIGLAVLRRLAP-FDVHLHYTDRH---RLPESVEK--- 231 Query: 361 FLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNAS 540 E +TW ++ E++ DV++L+ L T H+IN E L + K+ A +VN + Sbjct: 232 ------ELNLTWH--ATREDMYPVCDVVTLNCPLHPETEHMINDETLKLFKRGAYIVNTA 283 Query: 541 RGPVIDEVALVEHL 582 RG + D A+ L Sbjct: 284 RGKLCDRDAVARAL 297
>PDXB_BACTN (Q8A2E4) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 348 Score = 52.4 bits (124), Expect = 1e-06 Identities = 39/122 (31%), Positives = 64/122 (52%), Gaps = 4/122 (3%) Frame = +1 Query: 223 TVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKR 402 T+G+IG G +GS A++ + F M ++ DL R EK E +T+ Sbjct: 119 TIGIIGVGNVGSKVAKVA-QDFGMRVLLNDL---PREEK-------------EGNITF-- 159 Query: 403 ASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 570 +S+E++ E D+I+ H L K TYHL + ++++ V++N SRG VI+ AL Sbjct: 160 -TSLEKIAEECDIITFHVPLYKEGKYKTYHLADGNFFRSLQRKPVVINTSRGEVIETNAL 218 Query: 571 VE 576 +E Sbjct: 219 LE 220
>FDH2_YEAST (Q08987) Formate dehydrogenase 2 (EC 1.2.1.2) (NAD-dependent| formate dehydrogenase 2) Length = 376 Score = 52.0 bits (123), Expect = 1e-06 Identities = 45/184 (24%), Positives = 80/184 (43%), Gaps = 2/184 (1%) Frame = +1 Query: 7 VGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYD--G 180 VG +VD++AAN+ I + G + R Q G +D G Sbjct: 97 VGSDHVDLEAANERKITVTEVTGSNVVSVAEHVMATILVLIRNYNGGHQQAINGEWDIAG 156 Query: 181 WLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQ 360 + + L+ + + +GAGRIG ++ L+Y+D YQ E Sbjct: 157 VAKNEYD---LEDKIISTVGAGRIGYRVLERLVAFNPKKLLYYD-YQELPAEAINRLNEA 212 Query: 361 FLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNAS 540 NG + +R +E+++ ++DV++++ L K + L N + ++ MK A LVN + Sbjct: 213 SKLFNGRGDIV-QRVEKLEDMVAQSDVVTINCPLHKDSRGLFNKKLISHMKDGAYLVNTA 271 Query: 541 RGPV 552 RG + Sbjct: 272 RGAI 275
>FDH1_YEAST (Q08911) Formate dehydrogenase 1 (EC 1.2.1.2) (NAD-dependent| formate dehydrogenase 1) Length = 376 Score = 52.0 bits (123), Expect = 1e-06 Identities = 45/184 (24%), Positives = 80/184 (43%), Gaps = 2/184 (1%) Frame = +1 Query: 7 VGYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYD--G 180 VG +VD++AAN+ I + G + R Q G +D G Sbjct: 97 VGSDHVDLEAANERKITVTEVTGSNVVSVAEHVMATILVLIRNYNGGHQQAINGEWDIAG 156 Query: 181 WLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQ 360 + + L+ + + +GAGRIG ++ L+Y+D YQ E Sbjct: 157 VAKNEYD---LEDKIISTVGAGRIGYRVLERLVAFNPKKLLYYD-YQELPAEAINRLNEA 212 Query: 361 FLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNAS 540 NG + +R +E+++ ++DV++++ L K + L N + ++ MK A LVN + Sbjct: 213 SKLFNGRGDIV-QRVEKLEDMVAQSDVVTINCPLHKDSRGLFNKKLISHMKDGAYLVNTA 271 Query: 541 RGPV 552 RG + Sbjct: 272 RGAI 275
>PDXB_ERWCT (Q6D2N5) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 51.2 bits (121), Expect = 2e-06 Identities = 53/196 (27%), Positives = 78/196 (39%), Gaps = 5/196 (2%) Frame = +1 Query: 10 GYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 189 G +VD N NGIA PG + E D F Sbjct: 68 GTDHVDDTWLNANGIAFSAAPGC----NAIAVVEYVFSSLLMLAERDGFQ---------- 113 Query: 190 HLFVGNLLKGQTVGVIGAGRIGSAY-ARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 366 L+ +TVG++G G +G R+ G K L D ++ R + G FL Sbjct: 114 -------LRDKTVGIVGVGNVGRRLDTRLKAWGVKTLLC--DPPRADRGDA-----GDFL 159 Query: 367 KANGEQPVTWKRASSMEEVLREADVISLHPVL----DKTTYHLINPERLAMMKKEAVLVN 534 S+E ++R+AD+++LH L T+HL++ L +L+N Sbjct: 160 --------------SLETLVRDADILTLHTPLYLDGPYRTHHLVDATVLNAFADGRILIN 205 Query: 535 ASRGPVIDEVALVEHL 582 A RGPV+D AL+E L Sbjct: 206 ACRGPVVDNAALLEAL 221
>PDXB_BLOFL (Q7VRU9) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 372 Score = 49.3 bits (116), Expect = 8e-06 Identities = 35/121 (28%), Positives = 68/121 (56%), Gaps = 5/121 (4%) Frame = +1 Query: 211 LKGQTVGVIGAGRIGSA-YARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQP 387 L+ +TVG+IG G IG+ Y R+ G ++ + +D Y+S K + ++ Sbjct: 114 LRDKTVGIIGVGNIGNLLYQRLNSLG--VHTLLYDPYKS--------------KCDTDR- 156 Query: 388 VTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVI 555 ++WK S++ ++ ++D+++LH L T T+H+IN + L + ++L+N SRG V+ Sbjct: 157 MSWK---SLDILVSKSDILTLHVPLTYTGAYPTWHMINKDILDALPSNSILINTSRGAVV 213 Query: 556 D 558 + Sbjct: 214 N 214
>PDXB_WIGBR (Q8D2P6) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 47.8 bits (112), Expect = 2e-05 Identities = 51/196 (26%), Positives = 80/196 (40%), Gaps = 5/196 (2%) Frame = +1 Query: 10 GYXNVDVDAANKNGIAIGNTPGVLTETTXXXXXXXXXXXXRRIVEADQFMRAGLYDGWLP 189 G +VDVD KN I PG + A+ + LY + Sbjct: 68 GKDHVDVDWLKKNKINFDFAPGC-----------------NSVAVAEYVFSSMLYFAYRD 110 Query: 190 HLFVGNLLKGQTVGVIGAGRIGSAYARMMIE-GFKMNLIYFDLYQSTRLEKFVTAYGQFL 366 +LLK +TVG++G G IG + + G K L L + + Sbjct: 111 KF---SLLK-KTVGIVGFGNIGKCLNKKLSAIGVKTILCDPILEEKNNI----------- 155 Query: 367 KANGEQPVTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVN 534 + S+ E+++ +D+I+LH L + T+HLIN + L +K +L+N Sbjct: 156 -----------KLKSLNEIVQNSDIITLHVPLTYSGKYPTWHLINKKILLDLKDNCILIN 204 Query: 535 ASRGPVIDEVALVEHL 582 SRG VID +L+ L Sbjct: 205 TSRGSVIDNNSLLNIL 220
>YPRB2_CORML (P0C1E9) Hypothetical protein in proB 3'region (EC 1.-.-.-)| Length = 304 Score = 47.4 bits (111), Expect = 3e-05 Identities = 27/56 (48%), Positives = 32/56 (57%) Frame = +1 Query: 415 EEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHL 582 E V EADV L L TY ++N E L MK AVLVN RGP+I+ LV+ L Sbjct: 175 EHVWAEADVFVLILPLTDATYQIVNAETLGKMKPSAVLVNVGRGPLINTDDLVDAL 230
>PDXB_SHIFL (Q83QR1) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 46.6 bits (109), Expect = 5e-05 Identities = 34/128 (26%), Positives = 62/128 (48%), Gaps = 4/128 (3%) Frame = +1 Query: 202 GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGE 381 G L +TVG++G G +G + +E + + D ++ R ++ G F Sbjct: 111 GFSLHDRTVGIVGVGNVGRRL-QARLEALGIKTLLCDPPRADRGDE-----GDF------ 158 Query: 382 QPVTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGP 549 S++E+++ AD+++ H L K T HL + + + +K A+L+NA RG Sbjct: 159 --------RSLDELVQRADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGA 210 Query: 550 VIDEVALV 573 V+D AL+ Sbjct: 211 VVDNTALL 218
>Y2355_CORGL (P0C1E8) Hypothetical protein Cgl2355/cg2587 (EC 1.-.-.-)| Length = 304 Score = 46.2 bits (108), Expect = 7e-05 Identities = 26/56 (46%), Positives = 32/56 (57%) Frame = +1 Query: 415 EEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHL 582 E V EADV L L TY ++N E L MK AV+VN RGP+I+ LV+ L Sbjct: 175 EHVWAEADVFVLILPLTDATYQIVNAETLGKMKPSAVVVNVGRGPLINTDDLVDAL 230
>PDXB_ECOLI (P05459) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 46.2 bits (108), Expect = 7e-05 Identities = 34/128 (26%), Positives = 62/128 (48%), Gaps = 4/128 (3%) Frame = +1 Query: 202 GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGE 381 G L +TVG++G G +G + +E + + D ++ R ++ G F Sbjct: 111 GFSLYDRTVGIVGVGNVGRRL-QARLEALGIKTLLCDPPRADRGDE-----GDF------ 158 Query: 382 QPVTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGP 549 S++E+++ AD+++ H L K T HL + + + +K A+L+NA RG Sbjct: 159 --------RSLDELVQRADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGA 210 Query: 550 VIDEVALV 573 V+D AL+ Sbjct: 211 VVDNTALL 218
>PDXB_ECOL6 (Q8FFH2) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 46.2 bits (108), Expect = 7e-05 Identities = 34/128 (26%), Positives = 62/128 (48%), Gaps = 4/128 (3%) Frame = +1 Query: 202 GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGE 381 G L +TVG++G G +G + +E + + D ++ R ++ G F Sbjct: 111 GFSLHERTVGIVGVGNVGRRL-QARLEALGIKTLLCDPPRADRGDE-----GDF------ 158 Query: 382 QPVTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGP 549 S++E+++ AD+++ H L K T HL + + + +K A+L+NA RG Sbjct: 159 --------RSLDELVQHADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGA 210 Query: 550 VIDEVALV 573 V+D AL+ Sbjct: 211 VVDNTALL 218
>PDXB_COXBU (Q83AR8) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 366 Score = 45.1 bits (105), Expect = 2e-04 Identities = 26/55 (47%), Positives = 34/55 (61%), Gaps = 4/55 (7%) Frame = +1 Query: 424 LREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 576 L D++ LH L KT TYHLI+ L M+K +VL+NA RG VID AL++ Sbjct: 165 LANVDLVCLHTPLVKTGNFPTYHLIDNRFLKMLKPGSVLLNAGRGAVIDNNALLQ 219
>PDXB_ECO57 (Q8XCR0) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 43.1 bits (100), Expect = 6e-04 Identities = 33/128 (25%), Positives = 61/128 (47%), Gaps = 4/128 (3%) Frame = +1 Query: 202 GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGE 381 G L +TVG++G G +G + +E + + D ++ ++ G F Sbjct: 111 GFSLHERTVGIVGVGNVGRR-LQARLEALGIKTLLCDPPRADCGDE-----GDF------ 158 Query: 382 QPVTWKRASSMEEVLREADVISLHPVLDK----TTYHLINPERLAMMKKEAVLVNASRGP 549 S++E+++ AD+++ H L K T HL + + + +K A+L+NA RG Sbjct: 159 --------RSLDELVQRADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGA 210 Query: 550 VIDEVALV 573 V+D AL+ Sbjct: 211 VVDNTALL 218
>YP113_YEAST (Q02961) Putative 2-hydroxyacid dehydrogenase YPL113C (EC 1.-.-.-)| Length = 396 Score = 42.0 bits (97), Expect = 0.001 Identities = 32/117 (27%), Positives = 55/117 (47%) Frame = +1 Query: 232 VIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASS 411 ++G G IG + + F M++ Y+ ++ ++K + Y ++ + P TWK A Sbjct: 222 ILGFGSIGQNIGSNLHKVFNMSIEYYK--RTGPVQKSLLDYNAKYHSDLDDPNTWKNA-- 277 Query: 412 MEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHL 582 D+I L +T ++IN + LA K +VN RG IDE L++ L Sbjct: 278 --------DLIILALPSTASTNNIINRKSLAWCKDGVRIVNVGRGTCIDEDVLLDAL 326
>PDXB_PORGI (Q7MV70) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 377 Score = 39.7 bits (91), Expect = 0.006 Identities = 38/135 (28%), Positives = 58/135 (42%), Gaps = 11/135 (8%) Frame = +1 Query: 202 GNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYG-QFL---- 366 G LK + +G++G G +G L++ +AYG +FL Sbjct: 119 GFSLKEKVMGIVGVGHVGG-----------------------ELKRLASAYGMEFLLCDP 155 Query: 367 -KANGEQPVTWKRASSMEEVLREADVISLHPVL----DKTTYHLINPERL-AMMKKEAVL 528 ++ EQ ++ S + E + D+IS H L TYHLI L + K +L Sbjct: 156 PRSEAEQDNSFLPLSRLVE---QCDIISFHVPLTHEDPHATYHLIGEAFLRSCADKRPIL 212 Query: 529 VNASRGPVIDEVALV 573 +NA RG V D AL+ Sbjct: 213 INACRGAVADTQALI 227
>RGYR_THEMA (O51934) Reverse gyrase [Includes: Helicase (EC 3.6.1.-);| Topoisomerase (EC 5.99.1.3)] Length = 1104 Score = 31.6 bits (70), Expect = 1.7 Identities = 19/67 (28%), Positives = 34/67 (50%) Frame = +1 Query: 238 GAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSME 417 G GR S YA+++ F+ +Y D Y+ R +F +LK E+ VT + +E Sbjct: 1015 GIGR-PSTYAKIVEVLFRRGYVYEDKYKRVRPTRFGVMVYSYLKERYEKYVTEETTRRLE 1073 Query: 418 EVLREAD 438 E++ + + Sbjct: 1074 EIMDKVE 1080
>FAT_DROME (P33450) Cadherin-related tumor suppressor precursor (Protein fat)| Length = 5147 Score = 31.6 bits (70), Expect = 1.7 Identities = 18/65 (27%), Positives = 33/65 (50%) Frame = +1 Query: 310 DLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLIN 489 ++ +T L++ T+ + +T RASS+ + +DV P D TTY++ Sbjct: 2546 EISTATTLDREETSVYHLTLMAQDSSITEPRASSVNLTISVSDVNDNIPKFDSTTYNVAV 2605 Query: 490 PERLA 504 PER++ Sbjct: 2606 PERIS 2610
>MDH_GLOVI (Q7NHJ3) Malate dehydrogenase (EC 1.1.1.37)| Length = 325 Score = 30.0 bits (66), Expect = 5.0 Identities = 11/32 (34%), Positives = 22/32 (68%) Frame = +1 Query: 226 VGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQ 321 V ++GAG +GSA A+ +I+G +++ D+ + Sbjct: 11 VSILGAGNVGSALAQRLIQGNVADVVLLDIVE 42
>NODX_RHILV (P08888) Nodulation protein 10 (Nodulation protein X) (Probable| sugar acetylase) Length = 367 Score = 30.0 bits (66), Expect = 5.0 Identities = 22/85 (25%), Positives = 37/85 (43%), Gaps = 7/85 (8%) Frame = -3 Query: 554 ITGPRLAFTSTASFFIIASRSGFIRWYVVLSSTGCRLITSASLRTSSMLEALFHVTGCSP 375 +T + +S ASFF+ S F +V ++ L+ + L + +L+ LF+ T Sbjct: 67 VTDSYIRSSSAASFFVKRSLRIFPALFVNIAVMELALLVTGGLNVTGILQYLFYFTVYIL 126 Query: 374 LAFRNW-------PYAVTNFSSRVD 321 A R W PY ++ F D Sbjct: 127 TAARIWAVYFTYEPYTMSGFYGASD 151
>PYRB_BUCAI (P57450) Aspartate carbamoyltransferase catalytic chain (EC| 2.1.3.2) (Aspartate transcarbamylase) (ATCase) Length = 310 Score = 30.0 bits (66), Expect = 5.0 Identities = 28/124 (22%), Positives = 55/124 (44%), Gaps = 11/124 (8%) Frame = +1 Query: 226 VGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRA 405 VG + GR + + + + FK N YF + ++ ++ ++ + WKR Sbjct: 161 VGDLKYGRTVHSLTQALAK-FKHNKFYFISPDALKMPNYIN------NMLDKKEIYWKRH 213 Query: 406 SSMEEVLREADVISLHPV----LDKTTYHLINPERLAMMKKEAVLVNASRG-------PV 552 +++EE++ E D++ + + LD T Y + + + A+L NA P Sbjct: 214 NNIEEIISEIDILYMTRIQKERLDSTEY---ANAKSKFVLRAAILKNARNNMKILHPLPR 270 Query: 553 IDEV 564 IDE+ Sbjct: 271 IDEI 274
>MDH1_AQUAE (O67655) Malate dehydrogenase 1 (EC 1.1.1.37)| Length = 335 Score = 29.6 bits (65), Expect = 6.6 Identities = 17/49 (34%), Positives = 26/49 (53%) Frame = +1 Query: 220 QTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFL 366 +TV VIGAG +G A +++ N+ FDL + T + F G+ L Sbjct: 5 KTVAVIGAGNVGEHVASLILLKNLANVKMFDLPRKTEEKVFEPVKGKAL 53
>GPDA_BACSK (Q5WGU2) Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94)| (NAD(P)H-dependent glycerol-3-phosphate dehydrogenase) Length = 340 Score = 29.6 bits (65), Expect = 6.6 Identities = 33/112 (29%), Positives = 52/112 (46%), Gaps = 3/112 (2%) Frame = +1 Query: 220 QTVGVIGAGRIGSAYARMMIE-GFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTW 396 Q + VIGAG GSA A ++ + G + L+ Q L + T + N E P T Sbjct: 2 QKIAVIGAGSWGSALAMVLADNGHDVRLVGRRQEQMDELNERHT--NESYLPNIELPTTI 59 Query: 397 KRASSMEEVLR--EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRG 546 + + MEE L EA V+ + + T I P ++K +++AS+G Sbjct: 60 RGYTGMEEALGGVEAIVLVVPTKAMRETVRKIVP----YLQKAVPVIHASKG 107
>SAHH_SYNY3 (P74008) Adenosylhomocysteinase (EC 3.3.1.1)| (S-adenosyl-L-homocysteine hydrolase) (AdoHcyase) Length = 425 Score = 29.6 bits (65), Expect = 6.6 Identities = 26/110 (23%), Positives = 44/110 (40%) Frame = +1 Query: 208 LLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQP 387 LL G+T+ V G G G A M +G ++I ++ +E + + Sbjct: 211 LLAGKTIVVAGYGWCGKGVA-MRAKGMGADVIVTEISPVPAIEAAMDGF----------- 258 Query: 388 VTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 537 R M E + D+ + H+I PE A+MK A++ N+ Sbjct: 259 ----RVMPMAEAAHQGDIF----ITVTGNKHVIRPEHFAVMKDGAIVCNS 300
>ILVC_NEIMB (Q9JYI2) Ketol-acid reductoisomerase (EC 1.1.1.86)| (Acetohydroxy-acid isomeroreductase) (Alpha-keto-beta-hydroxylacil reductoisomerase) Length = 337 Score = 29.3 bits (64), Expect = 8.6 Identities = 32/111 (28%), Positives = 55/111 (49%) Frame = +1 Query: 205 NLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQ 384 +L+KG+TV +IG G G A+A + + +N++ L Q + +K A G +K Sbjct: 12 SLIKGKTVAIIGYGSQGHAHAANLKDS-GVNVV-IGLRQGSSWKK-AEAAGHVVK----- 63 Query: 385 PVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 537 ++ E +EADV+ L + D+T + + E A +K+ A L A Sbjct: 64 --------TVAEATKEADVVML-LLPDETMPAVYHAEVTANLKEGATLAFA 105
>ILVC_NEIMA (Q9JTI3) Ketol-acid reductoisomerase (EC 1.1.1.86)| (Acetohydroxy-acid isomeroreductase) (Alpha-keto-beta-hydroxylacil reductoisomerase) Length = 337 Score = 29.3 bits (64), Expect = 8.6 Identities = 32/111 (28%), Positives = 55/111 (49%) Frame = +1 Query: 205 NLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQ 384 +L+KG+TV +IG G G A+A + + +N++ L Q + +K A G +K Sbjct: 12 SLIKGKTVAIIGYGSQGHAHAANLKDS-GVNVV-IGLRQGSSWKK-AEAAGHVVK----- 63 Query: 385 PVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 537 ++ E +EADV+ L + D+T + + E A +K+ A L A Sbjct: 64 --------TVAEATKEADVVML-LLPDETMPAVYHAEVAANLKEGATLAFA 105
>SAHH_METKA (P58855) Adenosylhomocysteinase (EC 3.3.1.1)| (S-adenosyl-L-homocysteine hydrolase) (AdoHcyase) Length = 424 Score = 29.3 bits (64), Expect = 8.6 Identities = 32/125 (25%), Positives = 46/125 (36%), Gaps = 1/125 (0%) Frame = +1 Query: 208 LLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQP 387 LL G+TV V+G G G AR G N+I ++ +E + Sbjct: 209 LLAGKTVVVVGYGWCGRGIAR-RARGLGANVIVVEVDPIKAMEAIFDGF----------- 256 Query: 388 VTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPV-IDEV 564 R M+ E D+ + +I E + MK +L NA V ID+ Sbjct: 257 ----RVMPMDRAAEEGDIF----ITATGNRDVIRGEHIEKMKDGVILANAGHFDVEIDKE 308 Query: 565 ALVEH 579 L EH Sbjct: 309 YLEEH 313
>NUOL_BUCAI (P57262) NADH-quinone oxidoreductase chain L (EC 1.6.99.5) (NADH| dehydrogenase I, chain L) (NDH-1, chain L) Length = 614 Score = 29.3 bits (64), Expect = 8.6 Identities = 13/47 (27%), Positives = 22/47 (46%) Frame = -3 Query: 581 RCSTSATSSITGPRLAFTSTASFFIIASRSGFIRWYVVLSSTGCRLI 441 R S + I L T +F+++ + +G++RWYV G I Sbjct: 558 RLSADPLNKIINYFLKVTQIFNFYLLKTSNGYVRWYVASMILGINFI 604
>LDH_BACSU (P13714) L-lactate dehydrogenase (EC 1.1.1.27) (L-LDH)| Length = 320 Score = 29.3 bits (64), Expect = 8.6 Identities = 24/77 (31%), Positives = 41/77 (53%), Gaps = 2/77 (2%) Frame = +1 Query: 226 VGVIGAGRIGSAYARMMI-EGFKMNLIYFDLYQSTRL-EKFVTAYGQFLKANGEQPVTWK 399 V +IGAG +GS+YA +I +G L+ D+ + + + +G KA G QPV K Sbjct: 8 VALIGAGFVGSSYAFALINQGITDELVVIDVNKEKAMGDVMDLPHG---KAFGLQPV--K 62 Query: 400 RASSMEEVLREADVISL 450 + E ++AD++ + Sbjct: 63 TSYGTYEDCKDADIVCI 79
>SYM_ANASP (Q8Z068) Methionyl-tRNA synthetase (EC 6.1.1.10) (Methionine--tRNA| ligase) (MetRS) Length = 530 Score = 29.3 bits (64), Expect = 8.6 Identities = 18/43 (41%), Positives = 22/43 (51%), Gaps = 4/43 (9%) Frame = -2 Query: 429 PEDLLHAGSPLPC----HGLLTVSFQELAICCDEFLEPCGLVQ 313 P LL AG PLP HG LT Q++ ++P GLVQ Sbjct: 281 PAMLLSAGLPLPDRVFGHGFLTKDGQKMGKSLGNTVDPVGLVQ 323
>GID_STAAW (P64236) tRNA uridine 5-carboxymethylaminomethyl modification| enzyme gid Length = 435 Score = 29.3 bits (64), Expect = 8.6 Identities = 17/29 (58%), Positives = 19/29 (65%), Gaps = 1/29 (3%) Frame = +1 Query: 220 QTVGVIGAGRIGSAYARMMIE-GFKMNLI 303 QTV VIGAG GS A + E G K+NLI Sbjct: 3 QTVNVIGAGLAGSEAAYQLAERGIKVNLI 31
>GID_STAAS (Q6G9W2) tRNA uridine 5-carboxymethylaminomethyl modification| enzyme gid Length = 435 Score = 29.3 bits (64), Expect = 8.6 Identities = 17/29 (58%), Positives = 19/29 (65%), Gaps = 1/29 (3%) Frame = +1 Query: 220 QTVGVIGAGRIGSAYARMMIE-GFKMNLI 303 QTV VIGAG GS A + E G K+NLI Sbjct: 3 QTVNVIGAGLAGSEAAYQLAERGIKVNLI 31
>GID_STAAN (P64235) tRNA uridine 5-carboxymethylaminomethyl modification| enzyme gid Length = 435 Score = 29.3 bits (64), Expect = 8.6 Identities = 17/29 (58%), Positives = 19/29 (65%), Gaps = 1/29 (3%) Frame = +1 Query: 220 QTVGVIGAGRIGSAYARMMIE-GFKMNLI 303 QTV VIGAG GS A + E G K+NLI Sbjct: 3 QTVNVIGAGLAGSEAAYQLAERGIKVNLI 31
>GID_STAAM (P64234) tRNA uridine 5-carboxymethylaminomethyl modification| enzyme gid Length = 435 Score = 29.3 bits (64), Expect = 8.6 Identities = 17/29 (58%), Positives = 19/29 (65%), Gaps = 1/29 (3%) Frame = +1 Query: 220 QTVGVIGAGRIGSAYARMMIE-GFKMNLI 303 QTV VIGAG GS A + E G K+NLI Sbjct: 3 QTVNVIGAGLAGSEAAYQLAERGIKVNLI 31
>GID_STAAC (Q5HGI1) tRNA uridine 5-carboxymethylaminomethyl modification| enzyme gid Length = 435 Score = 29.3 bits (64), Expect = 8.6 Identities = 17/29 (58%), Positives = 19/29 (65%), Gaps = 1/29 (3%) Frame = +1 Query: 220 QTVGVIGAGRIGSAYARMMIE-GFKMNLI 303 QTV VIGAG GS A + E G K+NLI Sbjct: 3 QTVNVIGAGLAGSEAAYQLAERGIKVNLI 31 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 77,331,078 Number of Sequences: 219361 Number of extensions: 1491552 Number of successful extensions: 5114 Number of sequences better than 10.0: 135 Number of HSP's better than 10.0 without gapping: 4815 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4940 length of database: 80,573,946 effective HSP length: 106 effective length of database: 57,321,680 effective search space used: 4986986160 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
