ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | baal38k22 |
|---|---|
| Clone Library Name | barley_pub |
>CTPA_SYNY3 (Q55669) Carboxyl-terminal-processing protease precursor (EC| 3.4.21.102) Length = 427 Score = 67.0 bits (162), Expect(2) = 4e-23 Identities = 38/124 (30%), Positives = 68/124 (54%) Frame = +2 Query: 203 PRNIMSFKIGSDGNLQGVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNS 382 P + ++ + G L GVG+ IN +P T +L +M + G PA+ AG+ D+++ I+G Sbjct: 99 PEQYGNLQVTTTGELSGVGLQININPETNQLEIMAPLAGSPAEEAGLQPHDQILAIDGVD 158 Query: 383 VLGLDVEAVAQRLRGRAGTTVEVKLLDGTGIERSGRIKQKEVQLSREVINLSPLSTTIIX 562 L ++ A R+RG T V +++L +G +E L+R++I+LSP++ + Sbjct: 159 TQTLSLDEAAARMRGPKNTKVSLEILS------AGTEVPQEFTLTRQLISLSPVAAQLDD 212 Query: 563 HRFG 574 R G Sbjct: 213 SRPG 216 Score = 60.5 bits (145), Expect(2) = 4e-23 Identities = 26/73 (35%), Positives = 50/73 (68%) Frame = +1 Query: 7 QRTLVEAWGLIRETFVDPTFNHQDWDQKLQQTMVEMFPLKSADAAYGKISGMVSTLGDPF 186 Q+ L+++W L+ ++++D TFNHQ+W L++ V+ PL++ + Y I M++TL +PF Sbjct: 36 QKLLLQSWRLVNQSYLDETFNHQNW-WLLREKYVKR-PLRNREETYTAIEEMLATLDEPF 93 Query: 187 TKIITPKEYHEFQ 225 T+++ P++Y Q Sbjct: 94 TRLLRPEQYGNLQ 106
>YPEB_SYNP2 (P42784) Hypothetical protein in petB 5'region (Fragment)| Length = 411 Score = 62.0 bits (149), Expect(2) = 3e-21 Identities = 35/114 (30%), Positives = 61/114 (53%) Frame = +2 Query: 203 PRNIMSFKIGSDGNLQGVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNS 382 P S K+ + G L GVG+ IN +P L V+ + G PA+ AGI D+++ I+G Sbjct: 97 PEQYRSLKVSTSGELSGVGLQINVNPEVDVLEVILPLPGSPAEAAGIEAKDQILAIDGID 156 Query: 383 VLGLDVEAVAQRLRGRAGTTVEVKLLDGTGIERSGRIKQKEVQLSREVINLSPL 544 + +E A R+RG+ G+TV + ++ + V+++R+ I L+P+ Sbjct: 157 TRNIGLEEAAARMRGKKGSTVSLT------VKSPKTDTVRTVKVTRDTIALNPV 204 Score = 59.3 bits (142), Expect(2) = 3e-21 Identities = 26/73 (35%), Positives = 45/73 (61%) Frame = +1 Query: 7 QRTLVEAWGLIRETFVDPTFNHQDWDQKLQQTMVEMFPLKSADAAYGKISGMVSTLGDPF 186 Q L++AW + + +VD TFNHQ+W Q+ + PLK+ D AY + M++ L DP+ Sbjct: 34 QDLLLQAWRYVSQAYVDETFNHQNWWLIRQKFLKR--PLKTRDEAYEAVGEMLALLDDPY 91 Query: 187 TKIITPKEYHEFQ 225 T+++ P++Y + Sbjct: 92 TRLLRPEQYRSLK 104
>CTPAL_STAES (Q8CSK8) Probable ctpA-like serine protease (EC 3.4.21.-)| Length = 491 Score = 46.6 bits (109), Expect(2) = 6e-07 Identities = 26/105 (24%), Positives = 58/105 (55%) Frame = +2 Query: 221 FKIGSDGNLQGVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDV 400 F G G+ G+G + + ++ V + + PA++AGI D + ++N +SV+G + Sbjct: 122 FNEGVSGDFVGIGAEMQKK--NEQISVTSPMKDSPAEKAGIQPKDIVTQVNHHSVVGKPL 179 Query: 401 EAVAQRLRGRAGTTVEVKLLDGTGIERSGRIKQKEVQLSREVINL 535 + V + +RG+ GT V + + G+ ++K++++ R+ I++ Sbjct: 180 DQVVKMVRGKKGTYVTLTIKRGS--------QEKDIKIKRDTIHV 216 Score = 26.2 bits (56), Expect(2) = 6e-07 Identities = 11/32 (34%), Positives = 19/32 (59%) Frame = +1 Query: 151 ISGMVSTLGDPFTKIITPKEYHEFQDRKRWEF 246 I GMV L DP+++ +T +E +F + +F Sbjct: 99 IDGMVKELKDPYSEYMTAEETKQFNEGVSGDF 130
>CTPAL_STAEQ (Q5HPB7) Probable ctpA-like serine protease (EC 3.4.21.-)| Length = 491 Score = 46.6 bits (109), Expect(2) = 6e-07 Identities = 26/105 (24%), Positives = 58/105 (55%) Frame = +2 Query: 221 FKIGSDGNLQGVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDV 400 F G G+ G+G + + ++ V + + PA++AGI D + ++N +SV+G + Sbjct: 122 FNEGVSGDFVGIGAEMQKK--NEQISVTSPMKDSPAEKAGIQPKDIVTQVNHHSVVGKPL 179 Query: 401 EAVAQRLRGRAGTTVEVKLLDGTGIERSGRIKQKEVQLSREVINL 535 + V + +RG+ GT V + + G+ ++K++++ R+ I++ Sbjct: 180 DQVVKMVRGKKGTYVTLTIKRGS--------QEKDIKIKRDTIHV 216 Score = 26.2 bits (56), Expect(2) = 6e-07 Identities = 11/32 (34%), Positives = 19/32 (59%) Frame = +1 Query: 151 ISGMVSTLGDPFTKIITPKEYHEFQDRKRWEF 246 I GMV L DP+++ +T +E +F + +F Sbjct: 99 IDGMVKELKDPYSEYMTAEETKQFNEGVSGDF 130
>CTPAL_STAAW (Q8NWR2) Probable ctpA-like serine protease (EC 3.4.21.-)| Length = 496 Score = 53.1 bits (126), Expect = 6e-07 Identities = 30/106 (28%), Positives = 59/106 (55%) Frame = +2 Query: 218 SFKIGSDGNLQGVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSVLGLD 397 SF G G+ G+G + + +++V + + G PA+RAGI D + ++NG S+ G Sbjct: 126 SFNEGVSGDFVGIGAEMQKK--NDQIMVTSPMKGSPAERAGIRPKDVITKVNGKSIKGKA 183 Query: 398 VEAVAQRLRGRAGTTVEVKLLDGTGIERSGRIKQKEVQLSREVINL 535 ++ V + +RG+ T V + + G+ ++K+V++ RE I++ Sbjct: 184 LDEVVKDVRGKENTEVTLTVQRGS--------EEKDVKIKREKIHV 221
>CTPAL_STAAS (Q6G9E1) Probable ctpA-like serine protease (EC 3.4.21.-)| Length = 496 Score = 53.1 bits (126), Expect = 6e-07 Identities = 30/106 (28%), Positives = 59/106 (55%) Frame = +2 Query: 218 SFKIGSDGNLQGVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSVLGLD 397 SF G G+ G+G + + +++V + + G PA+RAGI D + ++NG S+ G Sbjct: 126 SFNEGVSGDFVGIGAEMQKK--NDQIMVTSPMKGSPAERAGIRPKDVITKVNGKSIKGKA 183 Query: 398 VEAVAQRLRGRAGTTVEVKLLDGTGIERSGRIKQKEVQLSREVINL 535 ++ V + +RG+ T V + + G+ ++K+V++ RE I++ Sbjct: 184 LDEVVKDVRGKENTEVTLTVQRGS--------EEKDVKIKREKIHV 221
>CTPAL_STAAR (Q6GGY8) Probable ctpA-like serine protease (EC 3.4.21.-)| Length = 496 Score = 53.1 bits (126), Expect = 6e-07 Identities = 30/106 (28%), Positives = 59/106 (55%) Frame = +2 Query: 218 SFKIGSDGNLQGVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSVLGLD 397 SF G G+ G+G + + +++V + + G PA+RAGI D + ++NG S+ G Sbjct: 126 SFNEGVSGDFVGIGAEMQKK--NDQIMVTSPMKGSPAERAGIRPKDVITKVNGKSIKGKA 183 Query: 398 VEAVAQRLRGRAGTTVEVKLLDGTGIERSGRIKQKEVQLSREVINL 535 ++ V + +RG+ T V + + G+ ++K+V++ RE I++ Sbjct: 184 LDEVVKDVRGKENTEVTLTVQRGS--------EEKDVKIKREKIHV 221
>CTPAL_STAAN (Q7A5M9) Probable ctpA-like serine protease (EC 3.4.21.-)| Length = 496 Score = 53.1 bits (126), Expect = 6e-07 Identities = 30/106 (28%), Positives = 59/106 (55%) Frame = +2 Query: 218 SFKIGSDGNLQGVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSVLGLD 397 SF G G+ G+G + + +++V + + G PA+RAGI D + ++NG S+ G Sbjct: 126 SFNEGVSGDFVGIGAEMQKK--NDQIMVTSPMKGSPAERAGIRPKDVITKVNGKSIKGKA 183 Query: 398 VEAVAQRLRGRAGTTVEVKLLDGTGIERSGRIKQKEVQLSREVINL 535 ++ V + +RG+ T V + + G+ ++K+V++ RE I++ Sbjct: 184 LDEVVKDVRGKENTEVTLTVQRGS--------EEKDVKIKREKIHV 221
>CTPAL_STAAM (Q99U67) Probable ctpA-like serine protease (EC 3.4.21.-)| Length = 496 Score = 53.1 bits (126), Expect = 6e-07 Identities = 30/106 (28%), Positives = 59/106 (55%) Frame = +2 Query: 218 SFKIGSDGNLQGVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSVLGLD 397 SF G G+ G+G + + +++V + + G PA+RAGI D + ++NG S+ G Sbjct: 126 SFNEGVSGDFVGIGAEMQKK--NDQIMVTSPMKGSPAERAGIRPKDVITKVNGKSIKGKA 183 Query: 398 VEAVAQRLRGRAGTTVEVKLLDGTGIERSGRIKQKEVQLSREVINL 535 ++ V + +RG+ T V + + G+ ++K+V++ RE I++ Sbjct: 184 LDEVVKDVRGKENTEVTLTVQRGS--------EEKDVKIKREKIHV 221
>CTPAL_STAAC (Q5HG01) Probable ctpA-like serine protease (EC 3.4.21.-)| Length = 496 Score = 53.1 bits (126), Expect = 6e-07 Identities = 30/106 (28%), Positives = 59/106 (55%) Frame = +2 Query: 218 SFKIGSDGNLQGVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSVLGLD 397 SF G G+ G+G + + +++V + + G PA+RAGI D + ++NG S+ G Sbjct: 126 SFNEGVSGDFVGIGAEMQKK--NDQIMVTSPMKGSPAERAGIRPKDVITKVNGKSIKGKA 183 Query: 398 VEAVAQRLRGRAGTTVEVKLLDGTGIERSGRIKQKEVQLSREVINL 535 ++ V + +RG+ T V + + G+ ++K+V++ RE I++ Sbjct: 184 LDEVVKDVRGKENTEVTLTVQRGS--------EEKDVKIKREKIHV 221
>CTPAL_STAAB (Q2YXZ9) Probable ctpA-like serine protease (EC 3.4.21.-)| Length = 496 Score = 53.1 bits (126), Expect = 6e-07 Identities = 30/106 (28%), Positives = 59/106 (55%) Frame = +2 Query: 218 SFKIGSDGNLQGVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSVLGLD 397 SF G G+ G+G + + +++V + + G PA+RAGI D + ++NG S+ G Sbjct: 126 SFNEGVSGDFVGIGAEMQKK--NDQIMVTSPMKGSPAERAGIRPKDVITKVNGKSIKGKA 183 Query: 398 VEAVAQRLRGRAGTTVEVKLLDGTGIERSGRIKQKEVQLSREVINL 535 ++ V + +RG+ T V + + G+ ++K+V++ RE I++ Sbjct: 184 LDEVVKDVRGKENTEVTLTVQRGS--------EEKDVKIKREKIHV 221
>MPP4_HUMAN (Q96JB8) MAGUK p55 subfamily member 4 (Discs large homolog 6)| (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein) Length = 637 Score = 52.8 bits (125), Expect = 8e-07 Identities = 32/67 (47%), Positives = 40/67 (59%), Gaps = 1/67 (1%) Frame = +2 Query: 242 NLQGVGIFINRDPATGRLLVMNCIDGGPADRAGI-HEGDELVEINGNSVLGLDVEAVAQR 418 N Q +G I R TG +LV I GG A+R+G+ + GD+LVE+NG SV GLD E V Sbjct: 160 NQQPLGATIKRHEMTGDILVARIIHGGLAERSGLLYAGDKLVEVNGVSVEGLDPEQVIHI 219 Query: 419 LRGRAGT 439 L GT Sbjct: 220 LAMSRGT 226
>MPP4_MOUSE (Q6P7F1) MAGUK p55 subfamily member 4 (Discs large homolog 6)| (MDLG6) Length = 635 Score = 51.6 bits (122), Expect = 2e-06 Identities = 31/67 (46%), Positives = 39/67 (58%), Gaps = 1/67 (1%) Frame = +2 Query: 242 NLQGVGIFINRDPATGRLLVMNCIDGGPADRAGI-HEGDELVEINGNSVLGLDVEAVAQR 418 N Q +G I R TG +LV I GG +R+G+ + GD+LVE+NG SV GLD E V Sbjct: 159 NQQPLGATIKRHEITGDILVARVIHGGLVERSGLLYAGDKLVEVNGVSVEGLDPEQVIHI 218 Query: 419 LRGRAGT 439 L GT Sbjct: 219 LAMSCGT 225
>MPP3_HUMAN (Q13368) MAGUK p55 subfamily member 3 (MPP3 protein) (Discs large| homolog 3) Length = 585 Score = 50.4 bits (119), Expect = 4e-06 Identities = 31/90 (34%), Positives = 53/90 (58%), Gaps = 1/90 (1%) Frame = +2 Query: 242 NLQGVGIFINRDPATGRLLVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQR 418 N + +G I RD +G ++V + GG ADR+G +H GDEL E+NG +VL + ++Q Sbjct: 143 NKEPLGATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREVNGIAVLHKRPDEISQI 202 Query: 419 LRGRAGTTVEVKLLDGTGIERSGRIKQKEV 508 L G ++ +K++ T + R+K+ +V Sbjct: 203 LAQSQG-SITLKIIPAT--QEEDRLKESKV 229
>CTPAL_STAHJ (Q4L6D0) Probable ctpA-like serine protease (EC 3.4.21.-)| Length = 496 Score = 49.3 bits (116), Expect = 8e-06 Identities = 27/106 (25%), Positives = 60/106 (56%) Frame = +2 Query: 218 SFKIGSDGNLQGVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSVLGLD 397 SF G+ G+G + + ++++ + + PA++AGI D + +++G SV+G Sbjct: 126 SFNEDVSGDFVGIGAEMQKKDK--QIMITSPMKDSPAEKAGIQPKDVVTKVDGKSVVGKP 183 Query: 398 VEAVAQRLRGRAGTTVEVKLLDGTGIERSGRIKQKEVQLSREVINL 535 ++ V + +RG+ GTTV++ + G+ ++KE+++ R I++ Sbjct: 184 LDQVVKLVRGKEGTTVKLTIKRGS--------QEKEIKIKRGKIHV 221
>MPP3_MOUSE (O88910) MAGUK p55 subfamily member 3 (MPP3 protein) (Dlgh3| protein) Length = 568 Score = 48.9 bits (115), Expect = 1e-05 Identities = 31/90 (34%), Positives = 51/90 (56%), Gaps = 1/90 (1%) Frame = +2 Query: 242 NLQGVGIFINRDPATGRLLVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQR 418 N + +G I RD +G ++V + GG ADR+G +H GDEL E+NG +VL + ++Q Sbjct: 143 NKEPLGATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREVNGIAVLHKRPDEISQI 202 Query: 419 LRGRAGTTVEVKLLDGTGIERSGRIKQKEV 508 L G ++ +K++ T + R K +V Sbjct: 203 LAQSQG-SITLKIIPAT--QEEDRFKDSKV 229
>MPP4_RAT (Q9QYH1) MAGUK p55 subfamily member 4 (Discs large homolog 6)| (rDLG6) Length = 441 Score = 48.5 bits (114), Expect = 1e-05 Identities = 30/67 (44%), Positives = 37/67 (55%), Gaps = 1/67 (1%) Frame = +2 Query: 242 NLQGVGIFINRDPATGRLLVMNCIDGGPADRAGI-HEGDELVEINGNSVLGLDVEAVAQR 418 N Q +G I R TG +LV I GG +R G+ + GD+LVE+NG V GLD E V Sbjct: 9 NQQPLGATIKRHEITGDILVARVIHGGLVERNGLLYAGDKLVEVNGVPVEGLDPEQVIHI 68 Query: 419 LRGRAGT 439 L GT Sbjct: 69 LAMSCGT 75
>CTPAL_STAS1 (Q49XN1) Probable ctpA-like serine protease (EC 3.4.21.-)| Length = 491 Score = 46.6 bits (109), Expect = 5e-05 Identities = 28/106 (26%), Positives = 57/106 (53%) Frame = +2 Query: 218 SFKIGSDGNLQGVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSVLGLD 397 SF G+ G+G + + ++ + + + PA++AGI D + ++NG S+ G Sbjct: 121 SFNEDVSGDFVGIGAEMQKKG--NQIQITSPMKQSPAEKAGIQPKDVVTKVNGKSIKGQP 178 Query: 398 VEAVAQRLRGRAGTTVEVKLLDGTGIERSGRIKQKEVQLSREVINL 535 +EA+ +++RG+ GT V + IER G + ++ + R+ I++ Sbjct: 179 LEAIVKKVRGKQGTKVTLT------IERGG--QAHDITIKRDKIHV 216
>CTPA_BARBA (Q44879) Carboxy-terminal-processing protease precursor (EC| 3.4.21.102) (C-terminal-processing protease) Length = 434 Score = 44.3 bits (103), Expect = 3e-04 Identities = 27/99 (27%), Positives = 51/99 (51%) Frame = +2 Query: 239 GNLQGVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQR 418 G G+GI + + + V++ ID PA +AG+ GD + +I+G + G + + Sbjct: 93 GEFGGLGIEVTME--NNLIKVVSPIDDTPAAKAGVLAGDFISKIDGKQISGQTLNEAVDQ 150 Query: 419 LRGRAGTTVEVKLLDGTGIERSGRIKQKEVQLSREVINL 535 +RG AGT + + I R G K ++++ R++I + Sbjct: 151 MRGPAGTPITLT------INRFGVDKPLDIKIVRDIIKV 183
>LAP4_HUMAN (Q14160) LAP4 protein (Scribble homolog protein) (hScrib)| Length = 1630 Score = 42.7 bits (99), Expect = 8e-04 Identities = 20/55 (36%), Positives = 35/55 (63%) Frame = +2 Query: 293 LLVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKL 457 + + + GPA RAG+ GD+L+E+NG ++ G + + LRG AGT V++++ Sbjct: 758 IFISRVSEEGPAARAGVRVGDKLLEVNGVALQGAEHHEAVEALRG-AGTAVQMRV 811 Score = 32.0 bits (71), Expect = 1.4 Identities = 23/66 (34%), Positives = 31/66 (46%), Gaps = 1/66 (1%) Frame = +2 Query: 272 RDPATGRLLVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVE 448 RDP + + G A R G + G L+E+N S+LGL Q LR G T+ Sbjct: 1127 RDPTDEGIFISKVSPTGAAGRDGRLRVGLRLLEVNQQSLLGLTHGEAVQLLRS-VGDTLT 1185 Query: 449 VKLLDG 466 V + DG Sbjct: 1186 VLVCDG 1191
>PDZK1_RABIT (Q865P3) PDZ domain-containing protein 1 (CFTR-associated protein| of 70 kDa) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3) Length = 518 Score = 42.7 bits (99), Expect = 8e-04 Identities = 30/98 (30%), Positives = 51/98 (52%), Gaps = 2/98 (2%) Frame = +2 Query: 248 QGVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRG 427 Q G F+ + T LV G PA++AG+ +GD ++ ING V + V +R Sbjct: 18 QNYGFFLRIEKDTEGHLVRVIEKGSPAEKAGLQDGDRVLRINGVFVDKEEHMQVVDLVR- 76 Query: 428 RAGTTVEVKLLDGTGIERS--GRIKQKEVQLSREVINL 535 ++G V + +LDG E++ ++ KE+ SR+ +L Sbjct: 77 KSGNAVTLLVLDGNSYEKAVKKQVDLKELGQSRQEADL 114 Score = 38.9 bits (89), Expect = 0.011 Identities = 22/84 (26%), Positives = 41/84 (48%) Frame = +2 Query: 212 IMSFKIGSDGNLQGVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSVLG 391 I+ K GS G G ++ P ++ + G PA+ AG+ D ++ +NG SV Sbjct: 243 IVEMKKGSSG----YGFYLKAGPEQRGQIIKDIDSGSPAEAAGLKNNDLVIAVNGKSVEA 298 Query: 392 LDVEAVAQRLRGRAGTTVEVKLLD 463 LD + V + ++ + G + ++D Sbjct: 299 LDHDGVVELIK-KGGDQTSLLVVD 321 Score = 35.8 bits (81), Expect = 0.095 Identities = 20/63 (31%), Positives = 29/63 (46%) Frame = +2 Query: 236 DGNLQGVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQ 415 D G G +N V G PAD AG+ + D ++E+NG +VL E V Sbjct: 382 DKGENGYGFHLNAIRGLPGSFVKEVQKGSPADLAGLEDEDIIIEVNGVNVLDEPYEKVVD 441 Query: 416 RLR 424 R++ Sbjct: 442 RIQ 444 Score = 32.3 bits (72), Expect = 1.1 Identities = 20/73 (27%), Positives = 39/73 (53%) Frame = +2 Query: 326 ADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLLDGTGIERSGRIKQKE 505 A +AG+ D L+E+NG +V E V ++++ ++G + L+D E R +++ Sbjct: 169 AMKAGVLADDHLIEVNGENVEDASHEEVVEKVK-KSGNRIVFLLVDK---ETEKRHSEQK 224 Query: 506 VQLSREVINLSPL 544 ++ RE +L L Sbjct: 225 IEFRREAASLKLL 237
>PDZK1_MOUSE (Q9JIL4) PDZ domain-containing protein 1 (CFTR-associated protein| of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3) Length = 519 Score = 42.4 bits (98), Expect = 0.001 Identities = 29/95 (30%), Positives = 52/95 (54%), Gaps = 4/95 (4%) Frame = +2 Query: 248 QGVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQ--RL 421 Q G F+ + T L+ +G PA++AG+ +GD ++ ING + +D E AQ L Sbjct: 18 QNYGFFLRIEKDTDGHLIRVIEEGSPAEKAGLLDGDRVLRING---VFVDKEEHAQVVEL 74 Query: 422 RGRAGTTVEVKLLDGTGIERS--GRIKQKEVQLSR 520 ++G +V + +LDG E++ ++ KE+ S+ Sbjct: 75 VRKSGNSVTLLVLDGDSYEKAVKNQVDLKELDQSQ 109 Score = 40.4 bits (93), Expect = 0.004 Identities = 21/71 (29%), Positives = 36/71 (50%) Frame = +2 Query: 251 GVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGR 430 G G ++ P ++ + G PA+ AG+ D +V +NG SV LD + V + +R + Sbjct: 252 GYGFYLRAGPEQKGQIIKDIEPGSPAEAAGLKNNDLVVAVNGKSVEALDHDGVVEMIR-K 310 Query: 431 AGTTVEVKLLD 463 G + +LD Sbjct: 311 GGDQTTLLVLD 321 Score = 36.2 bits (82), Expect = 0.073 Identities = 14/36 (38%), Positives = 24/36 (66%) Frame = +2 Query: 317 GGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLR 424 GGPAD+AG+ D ++E+NG +V + V +R++ Sbjct: 409 GGPADKAGLENEDVIIEVNGENVQEEPYDRVVERIK 444 Score = 31.2 bits (69), Expect = 2.3 Identities = 21/75 (28%), Positives = 39/75 (52%) Frame = +2 Query: 320 GPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLLDGTGIERSGRIKQ 499 G A +AG+ D L+E+NG +V E V +++ ++G+ + L+D E + + Sbjct: 167 GVAMKAGVLADDHLIEVNGENVENASHEEVVEKVT-KSGSRIMFLLVDK---ETARCHSE 222 Query: 500 KEVQLSREVINLSPL 544 ++ Q RE +L L Sbjct: 223 QKTQFKRETASLKLL 237
>MPP5_PONPY (Q5RDQ2) MAGUK p55 subfamily member 5| Length = 675 Score = 41.6 bits (96), Expect = 0.002 Identities = 20/50 (40%), Positives = 31/50 (62%), Gaps = 1/50 (2%) Frame = +2 Query: 293 LLVMNCIDGGPADRAGI-HEGDELVEINGNSVLGLDVEAVAQRLRGRAGT 439 +++ + GG A+++G+ HEGDE++EING + G DV V L GT Sbjct: 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLADMHGT 327
>MPP5_MOUSE (Q9JLB2) MAGUK p55 subfamily member 5 (Protein associated with| Lin-7 1) Length = 675 Score = 41.6 bits (96), Expect = 0.002 Identities = 20/50 (40%), Positives = 31/50 (62%), Gaps = 1/50 (2%) Frame = +2 Query: 293 LLVMNCIDGGPADRAGI-HEGDELVEINGNSVLGLDVEAVAQRLRGRAGT 439 +++ + GG A+++G+ HEGDE++EING + G DV V L GT Sbjct: 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGT 327
>MPP5_HUMAN (Q8N3R9) MAGUK p55 subfamily member 5| Length = 675 Score = 41.6 bits (96), Expect = 0.002 Identities = 20/50 (40%), Positives = 31/50 (62%), Gaps = 1/50 (2%) Frame = +2 Query: 293 LLVMNCIDGGPADRAGI-HEGDELVEINGNSVLGLDVEAVAQRLRGRAGT 439 +++ + GG A+++G+ HEGDE++EING + G DV V L GT Sbjct: 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGT 327
>PDZK1_RAT (Q9JJ40) PDZ domain-containing protein 1 (Na/Pi cotransporter| C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3) (Dietary Pi-regulated RNA-1) (Diphor-1) (C-termi Length = 523 Score = 41.2 bits (95), Expect = 0.002 Identities = 27/81 (33%), Positives = 45/81 (55%), Gaps = 2/81 (2%) Frame = +2 Query: 248 QGVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQ--RL 421 Q G F+ + T LV +G PA++AG+ +GD ++ ING + +D E AQ L Sbjct: 18 QNYGFFLRIEKDTDGHLVRVIEEGSPAEKAGLLDGDRVLRING---VFVDKEEHAQVVDL 74 Query: 422 RGRAGTTVEVKLLDGTGIERS 484 ++G +V + +LDG E++ Sbjct: 75 VRKSGNSVTLLVLDGDSYEKA 95 Score = 39.7 bits (91), Expect = 0.007 Identities = 19/64 (29%), Positives = 31/64 (48%) Frame = +2 Query: 251 GVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGR 430 G G ++ P ++ + G PA+ AG+ D +V +NG SV LD + V + +R Sbjct: 252 GYGFYLRAGPEQKGQIIKDIEPGSPAEAAGLKNNDLVVAVNGESVEALDHDGVVEMIRNG 311 Query: 431 AGTT 442 T Sbjct: 312 GDQT 315 Score = 36.2 bits (82), Expect = 0.073 Identities = 14/36 (38%), Positives = 24/36 (66%) Frame = +2 Query: 317 GGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLR 424 GGPAD+AG+ D ++E+NG +V + V +R++ Sbjct: 409 GGPADKAGLENEDIIIEVNGENVQDEPYDRVVERIK 444 Score = 29.3 bits (64), Expect = 8.9 Identities = 15/48 (31%), Positives = 28/48 (58%) Frame = +2 Query: 320 GPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLLD 463 G A +AG+ D L+E+NG +V E V +++ ++G+ + L+D Sbjct: 167 GVAMKAGVLADDHLIEVNGENVENASHEEVVEKVT-KSGSRIMFLLVD 213
>MAST2_MOUSE (Q60592) Microtubule-associated serine/threonine-protein kinase 2 (EC| 2.7.11.1) Length = 1734 Score = 41.2 bits (95), Expect = 0.002 Identities = 29/98 (29%), Positives = 48/98 (48%), Gaps = 6/98 (6%) Frame = +2 Query: 245 LQGVGIFI-NRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSVLGL-DVEAVAQR 418 L+ + +++ + D T +V + DGGPA AG+ +GD + +NG V GL E V Sbjct: 1056 LRAIRVYMGDTDVYTVHHMVWHVEDGGPASEAGLRQGDLITHVNGEPVHGLVHTEVVELV 1115 Query: 419 LRGRAGTTVEVKLLDGTGIE----RSGRIKQKEVQLSR 520 L+ ++ L+ T I+ R G K K + S+ Sbjct: 1116 LKSGNKVSISTTPLENTSIKVGPARKGSYKAKMARRSK 1153
>MAST2_HUMAN (Q6P0Q8) Microtubule-associated serine/threonine-protein kinase 2 (EC| 2.7.11.1) Length = 1798 Score = 40.8 bits (94), Expect = 0.003 Identities = 29/98 (29%), Positives = 47/98 (47%), Gaps = 6/98 (6%) Frame = +2 Query: 245 LQGVGIFI-NRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSVLGL-DVEAVAQR 418 L+ + +++ + D T +V + DGGPA AG+ +GD + +NG V GL E V Sbjct: 1118 LRAIRVYMGDSDVYTVHHMVWHVEDGGPASEAGLRQGDLITHVNGEPVHGLVHTEVVELI 1177 Query: 419 LRGRAGTTVEVKLLDGTGIE----RSGRIKQKEVQLSR 520 L+ + L+ T I+ R G K K + S+ Sbjct: 1178 LKSGNKVAISTTPLENTSIKVGPARKGSYKAKMARRSK 1215
>MPDZ_HUMAN (O75970) Multiple PDZ domain protein (Multi PDZ domain protein 1)| (Multi-PDZ-domain protein 1) Length = 2042 Score = 40.8 bits (94), Expect = 0.003 Identities = 33/105 (31%), Positives = 59/105 (56%), Gaps = 3/105 (2%) Frame = +2 Query: 179 TLSQRSSPP--RNIMSFKIGSDGNLQGVGIFINRDPATGRLLVMNCIDGGPADRAG-IHE 349 T+S S+P +++ + ++ +DG+ G GI + ATG ++V + GG AD+ G + Sbjct: 242 TISAHSNPVHWQHMETIELVNDGSGLGFGIIGGK--ATG-VIVKTILPGGVADQHGRLCS 298 Query: 350 GDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLLDGTGIERS 484 GD +++I + G+ E VAQ LR + G V++ + G ER+ Sbjct: 299 GDHILKIGDTDLAGMSSEQVAQVLR-QCGNRVKLMIARGAIEERT 342 Score = 37.4 bits (85), Expect = 0.033 Identities = 30/99 (30%), Positives = 50/99 (50%), Gaps = 3/99 (3%) Frame = +2 Query: 248 QGVGIFINRDPATGRLLVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQRLR 424 +G+G+ I + V + + GG AD G + +GD+++ +NG V EAVA L+ Sbjct: 1734 KGLGLSIVGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLK 1793 Query: 425 GRAGT-TVEV-KLLDGTGIERSGRIKQKEVQLSREVINL 535 GT T+EV ++ G+ S K+ L+ E+ L Sbjct: 1794 CSLGTVTLEVGRIKAGSSTSESLESSSKKNALASEIQGL 1832 Score = 33.1 bits (74), Expect = 0.62 Identities = 17/57 (29%), Positives = 32/57 (56%), Gaps = 1/57 (1%) Frame = +2 Query: 257 GIFINRDPATGRLLVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQRLR 424 G+ I+ + G + + + GP +G + GDEL+E+NG ++LG + + V L+ Sbjct: 564 GLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELLEVNGITLLGENHQDVVNILK 620 Score = 31.6 bits (70), Expect = 1.8 Identities = 16/60 (26%), Positives = 33/60 (55%), Gaps = 1/60 (1%) Frame = +2 Query: 275 DPATGRLLVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEV 451 DPA+ +++ + + GG A++ G + GD L+ +N ++ +E + L+G TV + Sbjct: 722 DPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEALKGAPSGTVRI 781
>MAST3_HUMAN (O60307) Microtubule-associated serine/threonine-protein kinase 3 (EC| 2.7.11.1) Length = 1309 Score = 40.4 bits (93), Expect = 0.004 Identities = 33/125 (26%), Positives = 57/125 (45%), Gaps = 17/125 (13%) Frame = +2 Query: 242 NLQGVGIFI-NRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSVLGL-DVEAVAQ 415 +L+ + +++ + D T +V + DG PA AG+ GD + ING SVLGL ++ V Sbjct: 963 SLRAIRVYMGDSDVYTVHHVVWSVEDGSPAQEAGLRAGDLITHINGESVLGLVHMDVVEL 1022 Query: 416 RLRGRAGTTVEVKLLDGTGIE---------------RSGRIKQKEVQLSREVINLSPLST 550 L+ ++ L+ T I+ RS R +++E Q R+ + Sbjct: 1023 LLKSGNKISLRTTALENTSIKVGPARKNVAKGRMARRSKRSRRRETQDRRKSLFKKISKQ 1082 Query: 551 TIIXH 565 T + H Sbjct: 1083 TSVLH 1087
>LIN2_CAEEL (P54936) Protein lin-2 (Abnormal cell lineage protein 2)| Length = 961 Score = 40.4 bits (93), Expect = 0.004 Identities = 25/63 (39%), Positives = 34/63 (53%), Gaps = 1/63 (1%) Frame = +2 Query: 251 GVGIFINRDPATGRLLVMNCIDGGPADR-AGIHEGDELVEINGNSVLGLDVEAVAQRLRG 427 G+ + +N D GR V + GG R A +H GDE+ EING SV VE++ + LR Sbjct: 558 GITLKVNED---GRCFVARIMHGGMIHRQATLHVGDEIREINGMSVANRSVESLQEMLRD 614 Query: 428 RAG 436 G Sbjct: 615 ARG 617
>USH1C_MOUSE (Q9ES64) Harmonin (Usher syndrome type-1C protein homolog) (PDZ| domain-containing protein) Length = 910 Score = 40.4 bits (93), Expect = 0.004 Identities = 22/70 (31%), Positives = 37/70 (52%), Gaps = 1/70 (1%) Frame = +2 Query: 248 QGVGIFINRDPATG-RLLVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLR 424 +G+G+ + G L + + I GG AD G+ GDE+V ING S+ E V +R Sbjct: 96 EGLGLSVRGGLEFGCGLFISHLIKGGQADSVGLQVGDEIVRINGYSISSCTHEEVINLIR 155 Query: 425 GRAGTTVEVK 454 + +++V+ Sbjct: 156 TKKTVSIKVR 165 Score = 35.0 bits (79), Expect = 0.16 Identities = 28/118 (23%), Positives = 52/118 (44%), Gaps = 6/118 (5%) Frame = +2 Query: 176 GTLSQRSSPPRNIMSFKIGSDGNLQGVGIFINRDPATGR-LLVMNCIDGGPADRAGIHEG 352 G+ R++ + + +GS +G+G I+ P + V + G + G+ G Sbjct: 200 GSPGNRTTKEKKVFISLVGS----RGLGCSISSGPIQKPGIFVSHVKPGSLSAEVGLETG 255 Query: 353 DELVEINGNSVLGLDVEAVAQRLRGRAGTTVEV-----KLLDGTGIERSGRIKQKEVQ 511 D++VE+NG LD + L+ T+ + + L T ER +Q+E+Q Sbjct: 256 DQIVEVNGIDFTNLDHKEAVNVLKSSRSLTISIVAGAGRELFMTDRERLEEARQRELQ 313 Score = 33.9 bits (76), Expect = 0.36 Identities = 22/86 (25%), Positives = 45/86 (52%), Gaps = 4/86 (4%) Frame = +2 Query: 206 RNIMSFKIGSDGNLQGVGIFINRDPATGRLLVMNCIDGGPADR-AGIHEGDELVEINGNS 382 +++ +I +G+L + + D G+++V +GG A+R G+ +GDE++ ING Sbjct: 751 KDVRLLRIKKEGSLD-LALEGGVDSPVGKVVVSAVYEGGAAERHGGVVKGDEIMAINGKI 809 Query: 383 VLG---LDVEAVAQRLRGRAGTTVEV 451 V + EA Q+ + G +++ Sbjct: 810 VTDYTLAEAEAALQKAWNQGGDWIDL 835
>USH1C_HUMAN (Q9Y6N9) Harmonin (Usher syndrome type-1C protein) (Autoimmune| enteropathy-related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen) Length = 552 Score = 40.4 bits (93), Expect = 0.004 Identities = 22/70 (31%), Positives = 37/70 (52%), Gaps = 1/70 (1%) Frame = +2 Query: 248 QGVGIFINRDPATG-RLLVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLR 424 +G+G+ + G L + + I GG AD G+ GDE+V ING S+ E V +R Sbjct: 96 EGLGLSVRGGLEFGCGLFISHLIKGGQADSVGLQVGDEIVRINGYSISSCTHEEVINLIR 155 Query: 425 GRAGTTVEVK 454 + +++V+ Sbjct: 156 TKKTVSIKVR 165 Score = 35.0 bits (79), Expect = 0.16 Identities = 27/118 (22%), Positives = 50/118 (42%), Gaps = 6/118 (5%) Frame = +2 Query: 176 GTLSQRSSPPRNIMSFKIGSDGNLQGVGIFINRDPATGR-LLVMNCIDGGPADRAGIHEG 352 G+ R + + + +GS +G+G I+ P + + + G + G+ G Sbjct: 200 GSPGNRENKEKKVFISLVGS----RGLGCSISSGPIQKPGIFISHVKPGSLSAEVGLEIG 255 Query: 353 DELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLLDG-----TGIERSGRIKQKEVQ 511 D++VE+NG LD + L+ T+ + G T ER +Q+E+Q Sbjct: 256 DQIVEVNGVDFSNLDHKEAVNVLKNSRSLTISIVAAAGRELFMTDRERLAEARQRELQ 313 Score = 29.6 bits (65), Expect = 6.8 Identities = 21/86 (24%), Positives = 44/86 (51%), Gaps = 4/86 (4%) Frame = +2 Query: 206 RNIMSFKIGSDGNLQGVGIFINRDPATGRLLVMNCIDGGPADR-AGIHEGDELVEINGNS 382 +++ +I +G+L + + D G+++V + G A+R GI +GDE++ ING Sbjct: 451 KDVRLLRIKKEGSLD-LALEGGVDSPIGKVVVSAVYERGAAERHGGIVKGDEIMAINGKI 509 Query: 383 VLG---LDVEAVAQRLRGRAGTTVEV 451 V + +A Q+ + G +++ Sbjct: 510 VTDYTLAEADAALQKAWNQGGDWIDL 535
>MPP5_BRARE (Q8JHF4) MAGUK p55 subfamily member 5 (Nagie oko protein) (MAGUK| family factor) Length = 677 Score = 40.4 bits (93), Expect = 0.004 Identities = 18/40 (45%), Positives = 28/40 (70%), Gaps = 1/40 (2%) Frame = +2 Query: 293 LLVMNCIDGGPADRAGI-HEGDELVEINGNSVLGLDVEAV 409 +++ + GG A+R+G+ HEGDE++EING + G DV V Sbjct: 280 VVISRIVKGGAAERSGLLHEGDEILEINGVEIRGKDVNEV 319
>MPDZ_MOUSE (Q8VBX6) Multiple PDZ domain protein (Multi PDZ domain protein 1)| (Multi-PDZ domain protein 1) Length = 2055 Score = 40.0 bits (92), Expect = 0.005 Identities = 31/99 (31%), Positives = 56/99 (56%), Gaps = 3/99 (3%) Frame = +2 Query: 179 TLSQRSSPP--RNIMSFKIGSDGNLQGVGIFINRDPATGRLLVMNCIDGGPADRAG-IHE 349 T+S S+P +++ + ++ +DG+ G GI + ATG ++V + GG AD+ G + Sbjct: 243 TISAHSNPMHWQHVETIELVNDGSGLGFGIIGGK--ATG-VIVKTILPGGVADQHGRLCS 299 Query: 350 GDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLLDG 466 GD +++I + G+ E VAQ LR + G V++ + G Sbjct: 300 GDHILKIGDTDLAGMSSEQVAQVLR-QCGNRVKLMIARG 337 Score = 33.1 bits (74), Expect = 0.62 Identities = 17/57 (29%), Positives = 32/57 (56%), Gaps = 1/57 (1%) Frame = +2 Query: 257 GIFINRDPATGRLLVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQRLR 424 G+ I+ + G + + + GP +G + GDEL+E+NG ++LG + + V L+ Sbjct: 557 GLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELLEVNGINLLGENHQDVVNILK 613 Score = 32.0 bits (71), Expect = 1.4 Identities = 23/70 (32%), Positives = 37/70 (52%), Gaps = 2/70 (2%) Frame = +2 Query: 248 QGVGIFINRDPATGRLLVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQRLR 424 +G+G+ I + V + + GG AD G + +GD+++ +NG V EAVA L+ Sbjct: 1719 KGLGLSIVGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRHATQEAVAALLK 1778 Query: 425 GRAG-TTVEV 451 G T+EV Sbjct: 1779 CSLGAVTLEV 1788
>MPDZ_RAT (O55164) Multiple PDZ domain protein (Multi PDZ domain protein 1)| (Multi-PDZ domain protein 1) Length = 2054 Score = 40.0 bits (92), Expect = 0.005 Identities = 31/99 (31%), Positives = 56/99 (56%), Gaps = 3/99 (3%) Frame = +2 Query: 179 TLSQRSSPP--RNIMSFKIGSDGNLQGVGIFINRDPATGRLLVMNCIDGGPADRAG-IHE 349 T+S S+P +++ + ++ +DG+ G GI + ATG ++V + GG AD+ G + Sbjct: 243 TVSAHSNPTHWQHVETIELVNDGSGLGFGIIGGK--ATG-VIVKTILPGGVADQHGRLCS 299 Query: 350 GDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLLDG 466 GD +++I + G+ E VAQ LR + G V++ + G Sbjct: 300 GDHILKIGDTDLAGMSSEQVAQVLR-QCGNRVKLMIARG 337 Score = 34.7 bits (78), Expect = 0.21 Identities = 24/70 (34%), Positives = 38/70 (54%), Gaps = 2/70 (2%) Frame = +2 Query: 248 QGVGIFINRDPATGRLLVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQRLR 424 +G+G+ I + V + + GG AD G + +GD+++ +NG V EAVA L+ Sbjct: 1718 KGLGLSIVGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLK 1777 Query: 425 GRAGT-TVEV 451 GT T+EV Sbjct: 1778 CSLGTVTLEV 1787 Score = 33.1 bits (74), Expect = 0.62 Identities = 17/57 (29%), Positives = 32/57 (56%), Gaps = 1/57 (1%) Frame = +2 Query: 257 GIFINRDPATGRLLVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQRLR 424 G+ I+ + G + + + GP +G + GDEL+E+NG ++LG + + V L+ Sbjct: 556 GLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELLEVNGINLLGENHQDVVNILK 612
>NHRF2_RABIT (Q8SQG9) Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (PDZ| domain containing protein NHERF-2) (Solute carrier family 9 isoform A3 regulatory factor 2) (Sodium-hydrogen exchanger regulatory factor 2) Length = 316 Score = 39.7 bits (91), Expect = 0.007 Identities = 21/65 (32%), Positives = 31/65 (47%) Frame = +2 Query: 248 QGVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRG 427 QG G ++ + + G PA+ A + GD LVE+NG +V G V QR++ Sbjct: 19 QGYGFHLHGEKGRRGQFIRRVEPGSPAEAAALRAGDRLVEVNGVNVEGETHHQVVQRIKA 78 Query: 428 RAGTT 442 G T Sbjct: 79 VEGET 83 Score = 37.0 bits (84), Expect = 0.043 Identities = 21/79 (26%), Positives = 36/79 (45%) Frame = +2 Query: 194 SSPPRNIMSFKIGSDGNLQGVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEIN 373 + PPR + QG G ++ D + + + G PA +G+ D L+E+N Sbjct: 141 NGPPRELRPRLCHLRKGPQGYGFNLHSDKSRPGQYIRSVDPGSPAAHSGLCAQDRLIEVN 200 Query: 374 GNSVLGLDVEAVAQRLRGR 430 G +V GL V R++ + Sbjct: 201 GQNVEGLRHAEVVARIKAK 219
>NHRF2_MOUSE (Q9JHL1) Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2)| (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP-1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3 Length = 337 Score = 39.7 bits (91), Expect = 0.007 Identities = 21/65 (32%), Positives = 31/65 (47%) Frame = +2 Query: 248 QGVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRG 427 QG G ++ + + G PA+ A + GD LVE+NG +V G V QR++ Sbjct: 19 QGYGFHLHGEKGRRGQFIRRVEPGSPAEAAALRAGDRLVEVNGVNVEGETHHQVVQRIKA 78 Query: 428 RAGTT 442 G T Sbjct: 79 VEGQT 83 Score = 37.4 bits (85), Expect = 0.033 Identities = 18/61 (29%), Positives = 31/61 (50%) Frame = +2 Query: 248 QGVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRG 427 QG G ++ D + + + G PA +G+ D L+E+NG +V GL V R++ Sbjct: 159 QGYGFNLHSDKSRPGQYIRSVDPGSPASHSGLRAQDRLIEVNGQNVEGLRHAEVVARIKA 218 Query: 428 R 430 + Sbjct: 219 Q 219
>NHRF2_HUMAN (Q15599) Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2)| (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP-1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3 Length = 337 Score = 39.7 bits (91), Expect = 0.007 Identities = 21/65 (32%), Positives = 31/65 (47%) Frame = +2 Query: 248 QGVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRG 427 QG G ++ + + G PA+ A + GD LVE+NG +V G V QR++ Sbjct: 19 QGYGFHLHGEKGRRGQFIRRVEPGSPAEAAALRAGDRLVEVNGVNVEGETHHQVVQRIKA 78 Query: 428 RAGTT 442 G T Sbjct: 79 VEGQT 83 Score = 37.7 bits (86), Expect = 0.025 Identities = 19/61 (31%), Positives = 31/61 (50%) Frame = +2 Query: 248 QGVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRG 427 QG G ++ D + + + G PA R+G+ D L+E+NG +V GL V ++ Sbjct: 159 QGYGFNLHSDKSRPGQYIRSVDPGSPAARSGLRAQDRLIEVNGQNVEGLRHAEVVASIKA 218 Query: 428 R 430 R Sbjct: 219 R 219
>PDZK1_HUMAN (Q5T2W1) PDZ domain-containing protein 1 (CFTR-associated protein| of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3) Length = 519 Score = 39.3 bits (90), Expect = 0.009 Identities = 30/99 (30%), Positives = 51/99 (51%), Gaps = 2/99 (2%) Frame = +2 Query: 248 QGVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRG 427 Q G F+ + T LV PA++AG+ +GD ++ ING V + V +R Sbjct: 18 QNYGFFLRIEKDTEGHLVRVVEKCSPAEKAGLQDGDRVLRINGVFVDKEEHMQVVDLVR- 76 Query: 428 RAGTTVEVKLLDGTGIERS--GRIKQKEVQLSREVINLS 538 ++G +V + +LDG E++ R+ KE+ S++ LS Sbjct: 77 KSGNSVTLLVLDGDSYEKAVKTRVDLKELGQSQKEQGLS 115 Score = 38.1 bits (87), Expect = 0.019 Identities = 23/84 (27%), Positives = 42/84 (50%) Frame = +2 Query: 212 IMSFKIGSDGNLQGVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSVLG 391 I+ K GS+G G ++ ++ + G PA+ AG+ D +V +NG SV Sbjct: 243 IVEMKKGSNG----YGFYLRAGSEQKGQIIKDIDSGSPAEEAGLKNNDLVVAVNGESVET 298 Query: 392 LDVEAVAQRLRGRAGTTVEVKLLD 463 LD ++V + +R + G + ++D Sbjct: 299 LDHDSVVEMIR-KGGDQTSLLVVD 321 Score = 37.7 bits (86), Expect = 0.025 Identities = 19/58 (32%), Positives = 29/58 (50%) Frame = +2 Query: 251 GVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLR 424 G G +N + GGPAD AG+ + D ++E+NG +VL E V R++ Sbjct: 387 GYGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDEDVIIEVNGVNVLDEPYEKVVDRIQ 444 Score = 36.6 bits (83), Expect = 0.056 Identities = 24/75 (32%), Positives = 41/75 (54%) Frame = +2 Query: 320 GPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLLDGTGIERSGRIKQ 499 G A RAG+ D L+E+NG +V E V ++++ ++G+ V L+D E R + Sbjct: 167 GVAMRAGVLADDHLIEVNGENVEDASHEEVVEKVK-KSGSRVMFLLVDK---ETDKRHVE 222 Query: 500 KEVQLSREVINLSPL 544 +++Q RE +L L Sbjct: 223 QKIQFKRETASLKLL 237
>ZO3_MOUSE (Q9QXY1) Tight junction protein ZO-3 (Zonula occludens 3 protein)| (Zona occludens 3 protein) (Tight junction protein 3) Length = 905 Score = 39.3 bits (90), Expect = 0.009 Identities = 28/82 (34%), Positives = 38/82 (46%), Gaps = 5/82 (6%) Frame = +2 Query: 197 SPPRNIMSFKIGSDGNLQ-----GVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDEL 361 SP ++SF G+ L+ VGIF++ A G PAD GI EGDE+ Sbjct: 366 SPDTRVVSFPKGASIGLRLAGGNDVGIFVSGVQA-----------GSPADGQGIQEGDEI 414 Query: 362 VEINGNSVLGLDVEAVAQRLRG 427 +++NG L E Q L G Sbjct: 415 LQVNGMPFRNLTREEAVQFLLG 436
>INADL_HUMAN (Q8NI35) InaD-like protein (Inadl protein) (hINADL)| (Pals1-associated tight junction protein) (Protein associated to tight junctions) Length = 1801 Score = 38.9 bits (89), Expect = 0.011 Identities = 25/65 (38%), Positives = 37/65 (56%), Gaps = 1/65 (1%) Frame = +2 Query: 233 SDGNLQGVGIFINRDPATGRLLVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAV 409 +DG+ G GI + T ++V + GG ADR G + GD +++I G +V G+ E V Sbjct: 253 NDGSGLGFGIVGGK---TSGVVVRTIVPGGLADRDGRLQTGDHILKIGGTNVQGMTSEQV 309 Query: 410 AQRLR 424 AQ LR Sbjct: 310 AQVLR 314 Score = 29.6 bits (65), Expect = 6.8 Identities = 17/64 (26%), Positives = 32/64 (50%), Gaps = 1/64 (1%) Frame = +2 Query: 248 QGVGIFINRDPATGRLLVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQRLR 424 +G+G+ I + + + + GG AD G + +GD+++ +NG + E VA L+ Sbjct: 1542 RGLGLSIVGKRNGSGVFISDIVKGGAADLDGRLIQGDQILSVNGEDMRNASQETVATILK 1601 Query: 425 GRAG 436 G Sbjct: 1602 CAQG 1605 Score = 29.6 bits (65), Expect = 6.8 Identities = 14/40 (35%), Positives = 21/40 (52%), Gaps = 1/40 (2%) Frame = +2 Query: 275 DPATGRLLVMNCIDGGPADRAG-IHEGDELVEINGNSVLG 391 D G + + + GGP D G + DEL+E+NG + G Sbjct: 575 DSFDGHHYISSIVSGGPVDTLGLLQPEDELLEVNGMQLYG 614 Score = 29.3 bits (64), Expect = 8.9 Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 1/64 (1%) Frame = +2 Query: 203 PRNIMSFKIGSDGNLQGVGIFINRDPATGRLLVMNCIDGGPADRAG-IHEGDELVEINGN 379 P + ++ D N G+ + N+D + + V+ GPA G + GDEL+EIN Sbjct: 1234 PGELHIIELEKDKNGLGLSLAGNKDRSRMSIFVVGINPEGPAAADGRMRIGDELLEINNQ 1293 Query: 380 SVLG 391 + G Sbjct: 1294 ILYG 1297
>PDZK2_MOUSE (Q99MJ6) PDZ domain-containing protein 2 (Natrium-phosphate| cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2) Length = 498 Score = 38.5 bits (88), Expect = 0.015 Identities = 26/75 (34%), Positives = 40/75 (53%), Gaps = 3/75 (4%) Frame = +2 Query: 248 QGVGIFINRDPAT-GRL--LVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQR 418 +G G + + GRL + + G PAD+AG+ GD LV + G SV GL E R Sbjct: 271 EGFGFLLREEKGLDGRLGQFLWDVDPGLPADKAGMKAGDRLVAVAGESVDGLGHEETVSR 330 Query: 419 LRGRAGTTVEVKLLD 463 +R + G+ V + ++D Sbjct: 331 IRAQ-GSCVSLIVVD 344 Score = 31.2 bits (69), Expect = 2.3 Identities = 15/35 (42%), Positives = 22/35 (62%) Frame = +2 Query: 317 GGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRL 421 GG A+RAG+ G L+E+NG SV L + ++L Sbjct: 186 GGAAERAGVPPGARLLEVNGASVEKLTYNQLNRKL 220
>NOS1_RABIT (O19132) Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I)| (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS) Length = 1435 Score = 38.5 bits (88), Expect = 0.015 Identities = 21/73 (28%), Positives = 40/73 (54%), Gaps = 1/73 (1%) Frame = +2 Query: 251 GVGIFINRDPATGRLLVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQRLRG 427 G+G + + +++ + I GG A+++G I GD ++ +NG ++ L ++ + LRG Sbjct: 27 GLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQAGDIILAVNGRPLVDLSYDSALEVLRG 86 Query: 428 RAGTTVEVKLLDG 466 A T V +L G Sbjct: 87 VASETHVVLILRG 99
>NOS1_HUMAN (P29475) Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I)| (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS) Length = 1434 Score = 38.5 bits (88), Expect = 0.015 Identities = 21/73 (28%), Positives = 40/73 (54%), Gaps = 1/73 (1%) Frame = +2 Query: 251 GVGIFINRDPATGRLLVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQRLRG 427 G+G + + +++ + I GG A+++G I GD ++ +NG ++ L ++ + LRG Sbjct: 27 GLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQAGDIILAVNGRPLVDLSYDSALEVLRG 86 Query: 428 RAGTTVEVKLLDG 466 A T V +L G Sbjct: 87 IASETHVVLILRG 99
>PDZK1_PONPY (Q5RCF7) PDZ domain-containing protein 1 (Na(+)/H(+) exchanger| regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3) Length = 519 Score = 38.1 bits (87), Expect = 0.019 Identities = 23/84 (27%), Positives = 42/84 (50%) Frame = +2 Query: 212 IMSFKIGSDGNLQGVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSVLG 391 I+ K GS+G G ++ ++ + G PA+ AG+ D +V +NG SV Sbjct: 243 IVEMKKGSNG----YGFYLRAGSEQKGQIIKDIDSGSPAEEAGLKNNDLVVAVNGESVET 298 Query: 392 LDVEAVAQRLRGRAGTTVEVKLLD 463 LD ++V + +R + G + ++D Sbjct: 299 LDHDSVVEMIR-KGGDQTSLLVVD 321 Score = 38.1 bits (87), Expect = 0.019 Identities = 27/89 (30%), Positives = 46/89 (51%), Gaps = 2/89 (2%) Frame = +2 Query: 248 QGVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRG 427 Q G F+ + T LV G PA++AG+ +GD ++ IN V + V +R Sbjct: 18 QNYGFFLRIEKDTEGHLVRVVEKGSPAEKAGLQDGDRVLRINDVFVDKEEHMQVVDLVR- 76 Query: 428 RAGTTVEVKLLDGTGIERS--GRIKQKEV 508 ++G +V + +LDG E++ R+ KE+ Sbjct: 77 KSGNSVTLLVLDGDSYEKAVKTRVDLKEL 105 Score = 37.7 bits (86), Expect = 0.025 Identities = 19/58 (32%), Positives = 29/58 (50%) Frame = +2 Query: 251 GVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLR 424 G G +N + GGPAD AG+ + D ++E+NG +VL E V R++ Sbjct: 387 GYGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDEDVIIEVNGVNVLDEPYEKVVDRIQ 444 Score = 33.5 bits (75), Expect = 0.47 Identities = 22/75 (29%), Positives = 40/75 (53%) Frame = +2 Query: 320 GPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLLDGTGIERSGRIKQ 499 G A +AG+ D L+E+NG +V E V ++++ ++G+ V L+D E + Sbjct: 167 GVAMKAGVLADDHLIEVNGENVEDASHEQVVEKVK-KSGSRVMFLLVDK---ETDKHHVE 222 Query: 500 KEVQLSREVINLSPL 544 +++Q RE +L L Sbjct: 223 QKIQFKRETASLKLL 237
>LAP4_MOUSE (Q80U72) LAP4 protein (Scribble homolog protein)| Length = 1612 Score = 38.1 bits (87), Expect = 0.019 Identities = 18/55 (32%), Positives = 33/55 (60%) Frame = +2 Query: 293 LLVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKL 457 + + + GPA RAG+ GD+L+E+NG ++ + + LRG AG V++++ Sbjct: 744 IFISRVSEEGPAARAGVRVGDKLLEVNGVALQDAEHHEAVEALRG-AGAAVQMRV 797 Score = 30.4 bits (67), Expect = 4.0 Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 1/65 (1%) Frame = +2 Query: 275 DPATGRLLVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEV 451 DP + + G A R G + G L+E+N S+LGL Q LR G T+ V Sbjct: 1114 DPTDEGIFISKVSPTGAAGRDGRLRVGLRLLEVNQQSLLGLTHAEAVQLLRS-VGDTLTV 1172 Query: 452 KLLDG 466 + DG Sbjct: 1173 LVCDG 1177
>PDZK2_HUMAN (Q86UT5) PDZ domain-containing protein 2 (Intestinal and| kidney-enriched PDZ protein) (DLNB27 protein) Length = 571 Score = 37.7 bits (86), Expect = 0.025 Identities = 20/49 (40%), Positives = 30/49 (61%) Frame = +2 Query: 317 GGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLLD 463 G PA +AG+ GD LV + G SV GL E R++G+ G+ V + ++D Sbjct: 363 GLPAKKAGMQAGDRLVAVAGESVEGLGHEETVSRIQGQ-GSCVSLTVVD 410 Score = 33.1 bits (74), Expect = 0.62 Identities = 18/43 (41%), Positives = 25/43 (58%), Gaps = 1/43 (2%) Frame = +2 Query: 290 RLLVMNCIDGGPADRAGIHEGDELVEINGNSVLGL-DVEAVAQ 415 RL + GG A RAG+ GD ++E+NG V G D+E + Q Sbjct: 490 RLFISQVTPGGSAARAGLQVGDVILEVNGYPVGGQNDLERLQQ 532 Score = 30.0 bits (66), Expect = 5.2 Identities = 13/23 (56%), Positives = 17/23 (73%) Frame = +2 Query: 317 GGPADRAGIHEGDELVEINGNSV 385 GG A+RAG+ G L+E+NG SV Sbjct: 252 GGAAERAGVPPGARLLEVNGVSV 274
>SHAN1_HUMAN (Q9Y566) SH3 and multiple ankyrin repeat domains protein 1 (Shank1)| (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP) Length = 2161 Score = 37.7 bits (86), Expect = 0.025 Identities = 23/62 (37%), Positives = 36/62 (58%), Gaps = 1/62 (1%) Frame = +2 Query: 278 PATGRLLVMNCID-GGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVK 454 PA L + +D GG A RAG+ GD L+E+NG +V+ + V +R + G T+ VK Sbjct: 694 PAFPALQYLESVDEGGVAWRAGLRMGDFLIEVNGQNVVKVGHRQVVNMIR-QGGNTLMVK 752 Query: 455 LL 460 ++ Sbjct: 753 VV 754
>APBA1_RAT (O35430) Amyloid beta A4 precursor protein-binding family A member| 1 (Neuron-specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint-1) (Adapter protein X11alpha) Length = 839 Score = 37.7 bits (86), Expect = 0.025 Identities = 15/46 (32%), Positives = 32/46 (69%), Gaps = 1/46 (2%) Frame = +2 Query: 293 LLVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQRLRG 427 +++ N + GGPA+++G ++ GD+++ ING S++GL + ++G Sbjct: 685 VIIANMMHGGPAEKSGKLNIGDQIMSINGTSLVGLPLSTCQSIIKG 730 Score = 34.3 bits (77), Expect = 0.28 Identities = 15/47 (31%), Positives = 25/47 (53%) Frame = +2 Query: 296 LVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAG 436 ++ + + GG A+R G+ G ++EING SV+ E + L G Sbjct: 769 IICSLMRGGIAERGGVRVGHRIIEINGQSVVATPHEKIVHILSNAVG 815
>SHAN1_RAT (Q9WV48) SH3 and multiple ankyrin repeat domains protein 1 (Shank1)| (GKAP/SAPAP-interacting protein) (SPANK-1) (Synamon) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP) Length = 2167 Score = 37.7 bits (86), Expect = 0.025 Identities = 23/62 (37%), Positives = 36/62 (58%), Gaps = 1/62 (1%) Frame = +2 Query: 278 PATGRLLVMNCID-GGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVK 454 PA L + +D GG A RAG+ GD L+E+NG +V+ + V +R + G T+ VK Sbjct: 694 PAFPALQYLESVDEGGVAWRAGLRMGDFLIEVNGQNVVKVGHRQVVNMIR-QGGNTLMVK 752 Query: 455 LL 460 ++ Sbjct: 753 VV 754
>APBA1_HUMAN (Q02410) Amyloid beta A4 precursor protein-binding family A member| 1 (Neuron-specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint-1) (Adapter protein X11alpha) Length = 837 Score = 37.7 bits (86), Expect = 0.025 Identities = 15/46 (32%), Positives = 32/46 (69%), Gaps = 1/46 (2%) Frame = +2 Query: 293 LLVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQRLRG 427 +++ N + GGPA+++G ++ GD+++ ING S++GL + ++G Sbjct: 683 VIIANMMHGGPAEKSGKLNIGDQIMSINGTSLVGLPLSTCQSIIKG 728 Score = 34.3 bits (77), Expect = 0.28 Identities = 15/47 (31%), Positives = 25/47 (53%) Frame = +2 Query: 296 LVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAG 436 ++ + + GG A+R G+ G ++EING SV+ E + L G Sbjct: 767 IICSLMRGGIAERGGVRVGHRIIEINGQSVVATPHEKIVHILSNAVG 813
>NHRF2_RAT (Q920G2) Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2)| (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP-1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KA Length = 337 Score = 37.7 bits (86), Expect = 0.025 Identities = 21/79 (26%), Positives = 36/79 (45%) Frame = +2 Query: 194 SSPPRNIMSFKIGSDGNLQGVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEIN 373 + PPR + QG G ++ D + + + G PA +G+ D L+E+N Sbjct: 141 NGPPRELRPRLCHLRRGPQGYGFNLHSDKSRPGQYIRSVDPGSPASLSGLRAQDRLIEVN 200 Query: 374 GNSVLGLDVEAVAQRLRGR 430 G +V GL V R++ + Sbjct: 201 GQNVEGLRHAEVVARIKAQ 219 Score = 37.7 bits (86), Expect = 0.025 Identities = 20/65 (30%), Positives = 30/65 (46%) Frame = +2 Query: 248 QGVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRG 427 QG G ++ + + G PA+ A + GD LVE+NG +V G V R++ Sbjct: 19 QGYGFHLHGEKGRRGQFIRRVEPGSPAEAAALRAGDRLVEVNGVNVEGETHHQVVHRIKA 78 Query: 428 RAGTT 442 G T Sbjct: 79 VEGQT 83
>DLG2_BRARE (Q5PYH7) Discs large homolog 2 (Postsynaptic density protein 93)| (PSD-93) Length = 881 Score = 37.4 bits (85), Expect = 0.033 Identities = 27/83 (32%), Positives = 43/83 (51%), Gaps = 1/83 (1%) Frame = +2 Query: 293 LLVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLLDGT 469 + V + GGPAD +G + GD+++ +NG + G E A L+G AG TV + + Sbjct: 447 IFVSFILAGGPADLSGELRRGDQILSVNGIDLRGATHEQAAAALKG-AGQTVTI--IAQY 503 Query: 470 GIERSGRIKQKEVQLSREVINLS 538 E GR + K L +++N S Sbjct: 504 RPEEYGRFEAKIHDLREQMMNHS 526
>NEB1_RAT (O35867) Neurabin-1 (Neurabin-I) (Neural tissue-specific| F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A) (p180) (PP1bp175) Length = 1095 Score = 37.4 bits (85), Expect = 0.033 Identities = 28/98 (28%), Positives = 46/98 (46%), Gaps = 1/98 (1%) Frame = +2 Query: 209 NIMSFKIGSDGNLQGVGIFINRDPATGRLLVMNCIDGGPADRAG-IHEGDELVEINGNSV 385 +I+ +G+D L+ +GIF V +GG A R G I D++VE++G S+ Sbjct: 518 SIIGMGVGADAGLEKLGIF-----------VKTVTEGGAAQRDGRIQVNDQIVEVDGISL 566 Query: 386 LGLDVEAVAQRLRGRAGTTVEVKLLDGTGIERSGRIKQ 499 +G+ A LR G V G E+ G++ + Sbjct: 567 VGVTQNFAATVLRNTKGNVRFV-----IGREKPGQVSE 599
>NEB1_HUMAN (Q9ULJ8) Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin| binding protein I) (Protein phosphatase 1 regulatory subunit 9A) Length = 1098 Score = 37.4 bits (85), Expect = 0.033 Identities = 28/98 (28%), Positives = 46/98 (46%), Gaps = 1/98 (1%) Frame = +2 Query: 209 NIMSFKIGSDGNLQGVGIFINRDPATGRLLVMNCIDGGPADRAG-IHEGDELVEINGNSV 385 +I+ +G+D L+ +GIF V +GG A R G I D++VE++G S+ Sbjct: 517 SIIGMGVGADAGLEKLGIF-----------VKTVTEGGAAQRDGRIQVNDQIVEVDGISL 565 Query: 386 LGLDVEAVAQRLRGRAGTTVEVKLLDGTGIERSGRIKQ 499 +G+ A LR G V G E+ G++ + Sbjct: 566 VGVTQNFAATVLRNTKGNVRFV-----IGREKPGQVSE 598
>INADL_MOUSE (Q63ZW7) InaD-like protein (Inadl protein) (Pals1-associated tight| junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein) Length = 1834 Score = 37.4 bits (85), Expect = 0.033 Identities = 24/65 (36%), Positives = 36/65 (55%), Gaps = 1/65 (1%) Frame = +2 Query: 233 SDGNLQGVGIFINRDPATGRLLVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAV 409 +DG+ G GI + ++V + GG ADR G + GD +++I G +V G+ E V Sbjct: 253 NDGSGLGFGIVGGKSSG---VVVRTIVPGGLADRDGRLQTGDHILKIGGTNVQGMTSEQV 309 Query: 410 AQRLR 424 AQ LR Sbjct: 310 AQVLR 314 Score = 29.3 bits (64), Expect = 8.9 Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 1/64 (1%) Frame = +2 Query: 203 PRNIMSFKIGSDGNLQGVGIFINRDPATGRLLVMNCIDGGPADRAG-IHEGDELVEINGN 379 P + ++ D N G+ + N+D + + V+ GPA G + GDEL+EIN Sbjct: 1240 PGELHIIELEKDKNGLGLSLAGNKDRSRMSIFVVGINPEGPAAADGRMRIGDELLEINNQ 1299 Query: 380 SVLG 391 + G Sbjct: 1300 ILYG 1303
>APBA2_PONPY (Q5RD33) Amyloid beta A4 precursor protein-binding family A member| 2 Length = 749 Score = 37.0 bits (84), Expect = 0.043 Identities = 20/56 (35%), Positives = 36/56 (64%), Gaps = 1/56 (1%) Frame = +2 Query: 293 LLVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKL 457 +++ N ++GGPA R+G + GD+++ ING S++GL + ++G T +VKL Sbjct: 595 VILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQT-QVKL 649 Score = 36.6 bits (83), Expect = 0.056 Identities = 16/47 (34%), Positives = 26/47 (55%) Frame = +2 Query: 296 LVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAG 436 ++ + + GG A+R G+ G ++EING SV+ E + Q L G Sbjct: 679 IICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSVG 725
>APBA2_HUMAN (Q99767) Amyloid beta A4 precursor protein-binding family A member| 2 (Neuron-specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta) Length = 749 Score = 37.0 bits (84), Expect = 0.043 Identities = 20/56 (35%), Positives = 36/56 (64%), Gaps = 1/56 (1%) Frame = +2 Query: 293 LLVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKL 457 +++ N ++GGPA R+G + GD+++ ING S++GL + ++G T +VKL Sbjct: 595 VILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQT-QVKL 649 Score = 36.6 bits (83), Expect = 0.056 Identities = 16/47 (34%), Positives = 26/47 (55%) Frame = +2 Query: 296 LVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAG 436 ++ + + GG A+R G+ G ++EING SV+ E + Q L G Sbjct: 679 IICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSVG 725
>APBA2_RAT (O35431) Amyloid beta A4 precursor protein-binding family A member| 2 (Neuron-specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta) Length = 750 Score = 37.0 bits (84), Expect = 0.043 Identities = 20/56 (35%), Positives = 36/56 (64%), Gaps = 1/56 (1%) Frame = +2 Query: 293 LLVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKL 457 +++ N ++GGPA R+G + GD+++ ING S++GL + ++G T +VKL Sbjct: 596 VILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQT-QVKL 650 Score = 36.6 bits (83), Expect = 0.056 Identities = 16/47 (34%), Positives = 26/47 (55%) Frame = +2 Query: 296 LVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAG 436 ++ + + GG A+R G+ G ++EING SV+ E + Q L G Sbjct: 680 IICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSVG 726
>APBA2_MOUSE (P98084) Amyloid beta A4 precursor protein-binding family A member| 2 (Neuron-specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta) Length = 750 Score = 37.0 bits (84), Expect = 0.043 Identities = 20/56 (35%), Positives = 36/56 (64%), Gaps = 1/56 (1%) Frame = +2 Query: 293 LLVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKL 457 +++ N ++GGPA R+G + GD+++ ING S++GL + ++G T +VKL Sbjct: 596 VILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQT-QVKL 650 Score = 36.6 bits (83), Expect = 0.056 Identities = 16/47 (34%), Positives = 26/47 (55%) Frame = +2 Query: 296 LVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAG 436 ++ + + GG A+R G+ G ++EING SV+ E + Q L G Sbjct: 680 IICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSVG 726
>APBA3_HUMAN (O96018) Amyloid beta A4 precursor protein-binding family A member| 3 (Neuron-specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma) Length = 575 Score = 37.0 bits (84), Expect = 0.043 Identities = 18/44 (40%), Positives = 28/44 (63%), Gaps = 1/44 (2%) Frame = +2 Query: 296 LVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQRLR 424 ++ N + GGPA+R+G + GD L ING S++GL + A +R Sbjct: 422 VIANLLHGGPAERSGALSIGDRLTAINGTSLVGLPLAACQAAVR 465 Score = 32.3 bits (72), Expect = 1.1 Identities = 13/31 (41%), Positives = 21/31 (67%) Frame = +2 Query: 296 LVMNCIDGGPADRAGIHEGDELVEINGNSVL 388 ++ + + GG A+R GI G ++EING SV+ Sbjct: 505 IICSLLRGGIAERGGIRVGHRIIEINGQSVV 535
>NHERF_MOUSE (P70441) Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50)| (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 Length = 354 Score = 36.6 bits (83), Expect = 0.056 Identities = 23/71 (32%), Positives = 39/71 (54%) Frame = +2 Query: 317 GGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLLDGTGIERSGRIK 496 G PA+++G+ GD LVE+NG +V + V R+R A V + ++D E R+K Sbjct: 44 GSPAEKSGLLAGDRLVEVNGENVEKETHQQVVSRIRA-ALNAVRLLVVDP---ETDERLK 99 Query: 497 QKEVQLSREVI 529 + V + E++ Sbjct: 100 KLGVSIREELL 110
>APBA3_RAT (O70248) Amyloid beta A4 precursor protein-binding family A member| 3 (Neuron-specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma) Length = 569 Score = 36.6 bits (83), Expect = 0.056 Identities = 18/56 (32%), Positives = 33/56 (58%), Gaps = 4/56 (7%) Frame = +2 Query: 296 LVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDV---EAVAQRLRGRAGTTVEV 451 ++ N + GGPA+R G + GD + ING S++GL + +A + +R + T+ + Sbjct: 417 VIANLLHGGPAERCGALSIGDRVTAINGTSLVGLSLAACQAAVREVRRHSSVTLSI 472
>Y1964_AQUAE (O67776) Hypothetical zinc metalloprotease aq_1964 (EC 3.4.24.-)| Length = 429 Score = 36.6 bits (83), Expect = 0.056 Identities = 21/81 (25%), Positives = 39/81 (48%) Frame = +2 Query: 317 GGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLLDGTGIERSGRIK 496 G PAD+ GI GD ++E+NG + + + +R G +++K+L + I Sbjct: 217 GSPADQVGIKPGDLILEVNGKKI--NTWYELVEEVRKSQGKAIKLKILRNGKMIEKELIP 274 Query: 497 QKEVQLSREVINLSPLSTTII 559 K+ + I L P + T++ Sbjct: 275 AKDPKTGTYFIGLFPKTETVV 295
>MUC2_HUMAN (Q02817) Mucin-2 precursor (Intestinal mucin 2)| Length = 5179 Score = 36.6 bits (83), Expect = 0.056 Identities = 31/100 (31%), Positives = 44/100 (44%), Gaps = 2/100 (2%) Frame = -2 Query: 525 TSRDSWTSFCFILPLLSIPVPSNSFTSTVVPARPLSL*ATASTSNPKTLFPLISTSSSPS 346 TSR + + LLS P+ TST P+ P A +TS TL P ST++SP Sbjct: 4223 TSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPT---APTTTSGGHTLSPPPSTTTSPP 4279 Query: 345 CMP--ALSAGPPSMQFITSKRPVAGSLFMNMPTPCKFPSL 232 P + G S ++ + S + PTP PS+ Sbjct: 4280 GTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSI 4319 Score = 33.1 bits (74), Expect = 0.62 Identities = 25/90 (27%), Positives = 39/90 (43%), Gaps = 3/90 (3%) Frame = -2 Query: 486 PLLSIPVPSNSFTSTVVPARPLSL*ATASTSNPKTLFPLISTSSSPSCMPALSAGPPSMQ 307 P + P+ + T+T+ P S T +T+ P T P T+++PS + PP Sbjct: 1620 PPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTT 1679 Query: 306 FITS---KRPVAGSLFMNMPTPCKFPSLPI 226 +S P + M P+P PS PI Sbjct: 1680 TPSSPITTTPSPPTTTMTTPSPTTTPSSPI 1709 Score = 29.6 bits (65), Expect = 6.8 Identities = 25/86 (29%), Positives = 34/86 (39%) Frame = -2 Query: 486 PLLSIPVPSNSFTSTVVPARPLSL*ATASTSNPKTLFPLISTSSSPSCMPALSAGPPSMQ 307 P + P P + T+T P S T + S P T S +++PS P + PS Sbjct: 1660 PTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPS-SPITTTTTPSST 1718 Query: 306 FITSKRPVAGSLFMNMPTPCKFPSLP 229 S P M P+P PS P Sbjct: 1719 TTPSPPPTT----MTTPSPTTTPSPP 1740 Score = 28.9 bits (63), Expect(2) = 1.6 Identities = 22/86 (25%), Positives = 35/86 (40%) Frame = -2 Query: 486 PLLSIPVPSNSFTSTVVPARPLSL*ATASTSNPKTLFPLISTSSSPSCMPALSAGPPSMQ 307 P + P+ + T+T+ P S T +T+ P T P T+++PS + PP Sbjct: 1541 PPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPP--- 1597 Query: 306 FITSKRPVAGSLFMNMPTPCKFPSLP 229 + P + P P PS P Sbjct: 1598 --PTTTPSPPTTTTTTPPPTTTPSPP 1621 Score = 21.2 bits (43), Expect(2) = 1.6 Identities = 10/33 (30%), Positives = 13/33 (39%) Frame = -1 Query: 178 PLAWTPXXXXXXXXRLPISAGTSPPSSAEVSGP 80 P TP PI+ T+PP + S P Sbjct: 1652 PPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSP 1684
>PDZK3_RAT (Q9QZR8) PDZ domain-containing protein 3 (PDZ domain-containing| protein 2) (Plakophilin-related armadillo repeat protein-interacting PDZ protein) Length = 2766 Score = 36.2 bits (82), Expect = 0.073 Identities = 31/99 (31%), Positives = 45/99 (45%), Gaps = 11/99 (11%) Frame = +2 Query: 131 QTPPTARSAGWCPR*GTLSQRSSPPRN----------IMSFKIGSDGNLQGVGIFINRDP 280 Q PP+A G PR TL RN ++ G +L G ++ + Sbjct: 2645 QEPPSANGKGPFPR-RTLPLEPGAGRNGAAHDALCVEVLKTSAGLGLSLDGGKSSVSGE- 2702 Query: 281 ATGRLLVMNCIDGGPADRAG-IHEGDELVEINGNSVLGL 394 G L++ GG A+RAG I GDE++ ING ++GL Sbjct: 2703 --GPLVIKRVYKGGAAERAGTIEAGDEILAINGKPLVGL 2739 Score = 33.9 bits (76), Expect = 0.36 Identities = 28/90 (31%), Positives = 41/90 (45%), Gaps = 5/90 (5%) Frame = +2 Query: 251 GVGIFINRDPATGR----LLVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQ 415 G+GI ++ + R ++V +GG A R G + GDEL+ ING+ ++GL E Sbjct: 343 GLGIQVSGGRGSKRSPHAIVVTQVKEGGAAHRDGRLSLGDELLVINGHLLVGLSHEEAVA 402 Query: 416 RLRGRAGTTVEVKLLDGTGIERSGRIKQKE 505 LR G V G E S + E Sbjct: 403 ILRSATGMVQLVVASKMPGSEESQDVGSSE 432 Score = 29.3 bits (64), Expect = 8.9 Identities = 19/53 (35%), Positives = 30/53 (56%), Gaps = 4/53 (7%) Frame = +2 Query: 314 DGGPADRAGIHEGDELVEINGNSVLGLDV-EAVAQRLRGRAG---TTVEVKLL 460 +G A+ + EGDE++++NG + GL EA+ + R+G TV KLL Sbjct: 571 NGSAAEDGRLKEGDEILDVNGIPIKGLTFQEAIHTFKQIRSGLFVLTVRTKLL 623
>NHERF_HUMAN (O14745) Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50)| (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 Length = 357 Score = 36.2 bits (82), Expect = 0.073 Identities = 23/71 (32%), Positives = 40/71 (56%) Frame = +2 Query: 317 GGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLLDGTGIERSGRIK 496 G PA++AG+ GD LVE+NG +V + V R+R A V + ++D E +++ Sbjct: 44 GSPAEKAGLLAGDRLVEVNGENVEKETHQQVVSRIRA-ALNAVRLLVVDP---ETDEQLQ 99 Query: 497 QKEVQLSREVI 529 + VQ+ E++ Sbjct: 100 KLGVQVREELL 110
>CNKR2_HUMAN (Q8WXI2) Connector enhancer of kinase suppressor of ras 2| (Connector enhancer of KSR2) (CNK2) Length = 1034 Score = 35.8 bits (81), Expect = 0.095 Identities = 18/60 (30%), Positives = 35/60 (58%), Gaps = 1/60 (1%) Frame = +2 Query: 248 QGVGIFINRDPATGRLLVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQRLR 424 +G+G++I + G ++ + PADR IH GDE++++N +V+G ++ + LR Sbjct: 225 EGLGMYI-KSTYDGLHVITGTTENSPADRCKKIHAGDEVIQVNHQTVVGWQLKNLVNALR 283
>APBA3_MOUSE (O88888) Amyloid beta A4 precursor protein-binding family A member| 3 (Neuron-specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma) Length = 571 Score = 35.8 bits (81), Expect = 0.095 Identities = 17/44 (38%), Positives = 27/44 (61%), Gaps = 1/44 (2%) Frame = +2 Query: 296 LVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQRLR 424 ++ N + GGPA+R G + GD + ING S++GL + A +R Sbjct: 419 VIANLLHGGPAERCGALSIGDRVTAINGTSLVGLSLAACQAAVR 462
>EM55_FUGRU (P49697) 55 kDa erythrocyte membrane protein (p55) (Membrane| protein, palmitoylated 1) Length = 467 Score = 35.8 bits (81), Expect = 0.095 Identities = 22/58 (37%), Positives = 32/58 (55%), Gaps = 1/58 (1%) Frame = +2 Query: 290 RLLVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLL 460 R V + GG R G +HEGDE+ EING SV V+ + + L+ G V +K++ Sbjct: 95 RCSVARILHGGMIHRQGSLHEGDEIAEINGKSVANQTVDQLQKILKETNG-VVTMKII 151
>DLG2_RAT (Q63622) Discs large homolog 2 (Postynaptic density protein PSD-93)| (Channel-associated protein of synapse-110) (Chapsyn-110) Length = 852 Score = 35.8 bits (81), Expect = 0.095 Identities = 20/54 (37%), Positives = 31/54 (57%), Gaps = 1/54 (1%) Frame = +2 Query: 293 LLVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEV 451 + V + GGPAD +G + GD+++ +NG + G E A L+G AG TV + Sbjct: 444 IFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHEQAAAALKG-AGQTVTI 496
>DLG2_MOUSE (Q91XM9) Discs large homolog 2 (Postsynaptic density protein| PSD-93) (Channel-associated protein of synapse-110) (Chapsyn-110) Length = 852 Score = 35.8 bits (81), Expect = 0.095 Identities = 20/54 (37%), Positives = 31/54 (57%), Gaps = 1/54 (1%) Frame = +2 Query: 293 LLVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEV 451 + V + GGPAD +G + GD+++ +NG + G E A L+G AG TV + Sbjct: 444 IFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHEQAAAALKG-AGQTVTI 496
>PTN13_HUMAN (Q12923) Tyrosine-protein phosphatase non-receptor type 13 (EC| 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1) Length = 2485 Score = 35.8 bits (81), Expect = 0.095 Identities = 28/96 (29%), Positives = 46/96 (47%), Gaps = 5/96 (5%) Frame = +2 Query: 194 SSPPR--NIMSFKIGSDGNLQGVGIF--INRDPATGRLLVMNCIDGGPADRAG-IHEGDE 358 SSPP+ +I ++ + N G+ + +N G + V I G A+ G IH+GD Sbjct: 1358 SSPPKPGDIFEVELAKNDNSLGISVTGGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDR 1417 Query: 359 LVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLLDG 466 ++ +NG S+ G + + LR G V + L G Sbjct: 1418 VLAVNGVSLEGATHKQAVETLR-NTGQVVHLLLEKG 1452 Score = 31.2 bits (69), Expect = 2.3 Identities = 18/46 (39%), Positives = 25/46 (54%), Gaps = 1/46 (2%) Frame = +2 Query: 299 VMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQRLRGRA 433 V G PA +G I GD ++++NG S+ GL + V LRG A Sbjct: 1533 VKKLFPGQPAAESGKIDVGDVILKVNGASLKGLSQQEVISALRGTA 1578
>DLG2_HUMAN (Q15700) Discs large homolog 2 (Postsynaptic density protein| PSD-93) (Channel-associated protein of synapse-110) (Chapsyn-110) Length = 870 Score = 35.8 bits (81), Expect = 0.095 Identities = 20/54 (37%), Positives = 31/54 (57%), Gaps = 1/54 (1%) Frame = +2 Query: 293 LLVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEV 451 + V + GGPAD +G + GD+++ +NG + G E A L+G AG TV + Sbjct: 444 IFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHEQAAAALKG-AGQTVTI 496
>CNKR2_RAT (Q9Z1T4) Connector enhancer of kinase suppressor of ras 2| (Connector enhancer of KSR2) (CNK2) (Membrane-associated guanylate kinase-interacting protein) (MAGUIN) Length = 1032 Score = 35.8 bits (81), Expect = 0.095 Identities = 18/60 (30%), Positives = 35/60 (58%), Gaps = 1/60 (1%) Frame = +2 Query: 248 QGVGIFINRDPATGRLLVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQRLR 424 +G+G++I + G ++ + PADR IH GDE++++N +V+G ++ + LR Sbjct: 225 EGLGMYI-KSTYDGLHVITGTTENSPADRCKKIHAGDEVIQVNHQTVVGWQLKNLVNALR 283
>CNKR2_MOUSE (Q80YA9) Connector enhancer of kinase suppressor of ras 2| (Connector enhancer of KSR2) (CNK2) Length = 1032 Score = 35.8 bits (81), Expect = 0.095 Identities = 18/60 (30%), Positives = 35/60 (58%), Gaps = 1/60 (1%) Frame = +2 Query: 248 QGVGIFINRDPATGRLLVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQRLR 424 +G+G++I + G ++ + PADR IH GDE++++N +V+G ++ + LR Sbjct: 225 EGLGMYI-KSTYDGLHVITGTTENSPADRCKKIHAGDEVIQVNHQTVVGWQLKNLVNALR 283
>LAP4_DROME (Q7KRY7) Protein lap4 (Protein scribble) (Protein smell-impaired)| Length = 1851 Score = 35.8 bits (81), Expect = 0.095 Identities = 24/99 (24%), Positives = 46/99 (46%), Gaps = 6/99 (6%) Frame = +2 Query: 293 LLVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEV------K 454 + + + GPAD AG+ GD+++++NG V+ D Q L+ V V + Sbjct: 761 IFISRVTEAGPADLAGLKVGDKVIKVNGIVVVDADHYQAVQVLKACGAVLVLVVQREVTR 820 Query: 455 LLDGTGIERSGRIKQKEVQLSREVINLSPLSTTIIXHRF 571 L+ G + Q V+ +R ++ +P + +I R+ Sbjct: 821 LIGHPVFSEDGSVSQISVE-TRPLVADAPPAASISHERY 858
>DGP14_ARATH (Q3E6S8) Putative protease Do-like 14 (EC 3.4.21.-)| Length = 459 Score = 35.4 bits (80), Expect = 0.12 Identities = 17/44 (38%), Positives = 26/44 (59%) Frame = +2 Query: 293 LLVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLR 424 +LV I G PADRAG GD +V +G V+ + + V +R++ Sbjct: 392 VLVPTVIPGSPADRAGFKPGDVVVRFDGKPVIEIMDDRVGKRMQ 435
>PSCBP_HUMAN (O60759) Pleckstrin homology Sec7 and coiled-coil domains-binding| protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein) Length = 359 Score = 35.4 bits (80), Expect = 0.12 Identities = 23/78 (29%), Positives = 39/78 (50%) Frame = +2 Query: 296 LVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLLDGTGI 475 L+ + PA AG+ GD L ING S G + V +R +G + ++ L+GT I Sbjct: 110 LICKIQEDSPAHCAGLQAGDVLANINGVSTEGFTYKQVVDLIRS-SGNLLTIETLNGTMI 168 Query: 476 ERSGRIKQKEVQLSREVI 529 +K+ E++ +V+ Sbjct: 169 -----LKRTELEAKLQVL 181
>NHERF_RABIT (Q28619) Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50)| (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 Length = 357 Score = 35.0 bits (79), Expect = 0.16 Identities = 16/36 (44%), Positives = 23/36 (63%) Frame = +2 Query: 317 GGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLR 424 G PA++AG+ GD LVE+NG +V + V R+R Sbjct: 44 GSPAEKAGLLAGDRLVEVNGENVEKETHQQVVSRIR 79
>PZRN4_HUMAN (Q6ZMN7) PDZ domain-containing RING finger protein 4 (Ligand of| Numb-protein X 4) (SEMACAP3-like protein) Length = 1036 Score = 34.7 bits (78), Expect = 0.21 Identities = 24/79 (30%), Positives = 39/79 (49%), Gaps = 1/79 (1%) Frame = +2 Query: 281 ATGRLLVMNCIDGGPADRA-GIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKL 457 +T + V ++ GPADRA G+ D+++E+NG + E + R A + V++ Sbjct: 252 STEGIYVSKILENGPADRADGLEIHDKIMEVNGKDLSKATHEEAVEAFR-NAKEPIVVQV 310 Query: 458 LDGTGIERSGRIKQKEVQL 514 L T + R EVQL Sbjct: 311 LRRTPLSRPAYGMASEVQL 329
>NHERF_RAT (Q9JJ19) Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50)| (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 is Length = 355 Score = 34.7 bits (78), Expect = 0.21 Identities = 22/71 (30%), Positives = 39/71 (54%) Frame = +2 Query: 317 GGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLLDGTGIERSGRIK 496 G PA+++G+ GD LVE+NG +V + V R+R A V + ++D E ++K Sbjct: 44 GSPAEKSGLLAGDRLVEVNGENVEKETHQQVVSRIRA-ALNAVRLLVVDP---ETDEQLK 99 Query: 497 QKEVQLSREVI 529 + V + E++ Sbjct: 100 KLGVPIREELL 110
>DLG1L_BRARE (Q5PYH5) Discs large homolog 1-like protein (Synapse-associated| protein 97B) (SAP-97B) Length = 827 Score = 34.7 bits (78), Expect = 0.21 Identities = 26/72 (36%), Positives = 34/72 (47%), Gaps = 1/72 (1%) Frame = +2 Query: 239 GNLQGVGIFINRDPATGRLLVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQ 415 G G GIFI+ + GGPAD G + +GD LV +NG + G E A Sbjct: 419 GGEDGEGIFISF-----------ILAGGPADLCGELRKGDRLVSVNGIDLRGATHEQAAA 467 Query: 416 RLRGRAGTTVEV 451 L+ AG TV + Sbjct: 468 ALK-NAGQTVTI 478
>HTRA_BACSU (O34358) Probable serine protease do-like htrA (EC 3.4.21.-)| Length = 449 Score = 34.7 bits (78), Expect = 0.21 Identities = 28/107 (26%), Positives = 54/107 (50%), Gaps = 2/107 (1%) Frame = +2 Query: 203 PRNIMSFKIGSDGNLQGVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNS 382 P+N +G G+ G++I R+ A+G PA++AG+ D ++ + G Sbjct: 355 PQNYQEGTLGLFGSQLNKGVYI-REVASG----------SPAEKAGLKAEDIIIGLKGKE 403 Query: 383 V-LGLDVEAVAQRLRGRAGTTVEVKLL-DGTGIERSGRIKQKEVQLS 517 + G ++ + + + G TVEVK+L +G + + ++ QKE + S Sbjct: 404 IDTGSELRNILYK-DAKIGDTVEVKILRNGKEMTKKIKLDQKEEKTS 449
>PSCBP_RAT (Q5I0L6) Pleckstrin homology Sec7 and coiled-coil domain-binding| protein Length = 359 Score = 34.3 bits (77), Expect = 0.28 Identities = 22/80 (27%), Positives = 38/80 (47%), Gaps = 2/80 (2%) Frame = +2 Query: 269 NRDPATGRLLVMNCI--DGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTT 442 N++ + + M C + PA AG+ GD +NG S G + V +R +G Sbjct: 99 NQNICSSEVCTMICKVQEDSPAHCAGLQVGDIFANVNGVSTEGFTHKQVVDLIRS-SGNL 157 Query: 443 VEVKLLDGTGIERSGRIKQK 502 + ++ L+GT I R ++ K Sbjct: 158 LTIETLNGTMIHRRAELEAK 177
>PSCBP_MOUSE (Q91VY6) Pleckstrin homology Sec7 and coiled-coil domains-binding| protein (Cytohesin-binding protein HE) (Cbp) Length = 359 Score = 34.3 bits (77), Expect = 0.28 Identities = 22/80 (27%), Positives = 38/80 (47%), Gaps = 2/80 (2%) Frame = +2 Query: 269 NRDPATGRLLVMNCI--DGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTT 442 N++ + + M C + PA AG+ GD +NG S G + V +R +G Sbjct: 99 NQNICSSEVCTMICKVQEDSPAHCAGLQVGDIFANVNGVSTEGFTHKQVVDLIRS-SGNL 157 Query: 443 VEVKLLDGTGIERSGRIKQK 502 + ++ L+GT I R ++ K Sbjct: 158 LTIETLNGTMIHRRAELEAK 177
>MAGI2_RAT (O88382) Membrane-associated guanylate kinase, WW and PDZ| domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Synaptic scaffolding molecule) (S-SCAM) Length = 1277 Score = 34.3 bits (77), Expect = 0.28 Identities = 28/108 (25%), Positives = 52/108 (48%), Gaps = 16/108 (14%) Frame = +2 Query: 185 SQRSSPPRNIMSFKIGSDGNL------QGVGIFI----NRDPATGRLLVM-----NCIDG 319 S +SPP S + + + +G G I NR P +G + + IDG Sbjct: 902 SNNASPPEGFASHSLQTSDVIIHRKENEGFGFVIISSLNR-PESGATITVPHKIGRIIDG 960 Query: 320 GPADR-AGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLL 460 PADR A + GD ++ +NG S++ + + + ++ AG +V ++++ Sbjct: 961 SPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKD-AGLSVTLRII 1007 Score = 33.1 bits (74), Expect = 0.62 Identities = 30/96 (31%), Positives = 43/96 (44%), Gaps = 6/96 (6%) Frame = +2 Query: 203 PRNIMSFKIGSDGNLQGVGIFINRDPATGR-----LLVMNCIDGGPADRAG-IHEGDELV 364 P++ F + + +G G I GR L V+ + GPA R G + GD+++ Sbjct: 1134 PQDFDYFTVDMEKGAKGFGFSIRG----GREYKMDLYVLRLAEDGPAIRNGRMRVGDQII 1189 Query: 365 EINGNSVLGLDVEAVAQRLRGRAGTTVEVKLLDGTG 472 EING S + A A L G V + L GTG Sbjct: 1190 EINGESTRDM-THARAIELIKSGGRRVRLLLKRGTG 1224 Score = 31.6 bits (70), Expect = 1.8 Identities = 35/114 (30%), Positives = 53/114 (46%), Gaps = 20/114 (17%) Frame = +2 Query: 185 SQRSSPPRNIMSFKIGSDG-NLQGVGIFINR------------DPATGRLLVMNCIDGGP 325 S++ PPR SF++ S G + + + + + R D +L+ I G Sbjct: 755 SRQQVPPRT--SFRMDSSGPDYKELDVHLRRMESGFGFRILGGDEPGQPILIGAVIAMGS 812 Query: 326 ADRAG-IHEGDELVEINGNSVLG------LDVEAVAQRLRGRAGTTVEVKLLDG 466 ADR G +H GDELV ++G V G +D+ A R G+ TV K+L G Sbjct: 813 ADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAAR-NGQVNLTVRRKVLCG 865
>PDZK3_HUMAN (O15018) PDZ domain-containing protein 3 (PDZ domain-containing| protein 2) (Activated in prostate cancer protein) Length = 2839 Score = 33.9 bits (76), Expect = 0.36 Identities = 17/37 (45%), Positives = 25/37 (67%), Gaps = 1/37 (2%) Frame = +2 Query: 287 GRLLVMNCIDGGPADRAGIHE-GDELVEINGNSVLGL 394 G L++ GG A++AGI E GDE++ ING ++GL Sbjct: 2775 GPLVIKRVYKGGAAEQAGIIEAGDEILAINGKPLVGL 2811 Score = 32.7 bits (73), Expect = 0.81 Identities = 23/67 (34%), Positives = 35/67 (52%), Gaps = 5/67 (7%) Frame = +2 Query: 251 GVGIFINRDPATGR----LLVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQ 415 G+GI ++ + R ++V +GG A R G + GDEL+ ING+ ++GL E Sbjct: 343 GLGIQVSGGRGSKRSPHAIVVTQVKEGGAAHRDGRLSLGDELLVINGHLLVGLSHEEAVA 402 Query: 416 RLRGRAG 436 LR G Sbjct: 403 ILRSATG 409
>LIN7B_HUMAN (Q9HAP6) LIN-7 homolog B (LIN-7B) (hLin7B) (Mammalian LIN-seven| protein 2) (MALS-2) (Vertebrate LIN 7 homolog 2) (Veli-2 protein) (hVeli2) Length = 207 Score = 33.9 bits (76), Expect = 0.36 Identities = 18/50 (36%), Positives = 27/50 (54%), Gaps = 1/50 (2%) Frame = +2 Query: 293 LLVMNCIDGGPADR-AGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGT 439 + + I GG ADR G+ GD+L+ +NG SV G E + L+ G+ Sbjct: 117 IYISRVIPGGVADRHGGLKRGDQLLSVNGVSVEGEQHEKAVELLKAAQGS 166
>LIN10_CAEEL (O17583) Protein lin-10 (Abnormal cell lineage protein 10)| Length = 982 Score = 33.9 bits (76), Expect = 0.36 Identities = 15/47 (31%), Positives = 26/47 (55%) Frame = +2 Query: 296 LVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAG 436 ++ + + GG A+R GI G ++EING SV+ + + + L G Sbjct: 912 VICSLLRGGIAERGGIRVGHRIIEINGTSVVAVAHDRIVNMLATAVG 958
>MAGI2_MOUSE (Q9WVQ1) Membrane-associated guanylate kinase, WW and PDZ| domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1) Length = 1275 Score = 33.9 bits (76), Expect = 0.36 Identities = 28/108 (25%), Positives = 52/108 (48%), Gaps = 16/108 (14%) Frame = +2 Query: 185 SQRSSPPRNIMSFKIGSDGNL------QGVGIFI----NRDPATGRLLVM-----NCIDG 319 S +SPP S + + + +G G I NR P +G + + IDG Sbjct: 901 SSNASPPEGFASHSLQTSDVVIHRKENEGFGFVIISSLNR-PESGATITVPHKIGRIIDG 959 Query: 320 GPADR-AGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLL 460 PADR A + GD ++ +NG S++ + + + ++ AG +V ++++ Sbjct: 960 SPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKD-AGLSVTLRII 1006 Score = 33.1 bits (74), Expect = 0.62 Identities = 30/96 (31%), Positives = 43/96 (44%), Gaps = 6/96 (6%) Frame = +2 Query: 203 PRNIMSFKIGSDGNLQGVGIFINRDPATGR-----LLVMNCIDGGPADRAG-IHEGDELV 364 P++ F + + +G G I GR L V+ + GPA R G + GD+++ Sbjct: 1132 PQDFDYFTVDMEKGAKGFGFSIRG----GREYKMDLYVLRLAEDGPAIRNGRMRVGDQII 1187 Query: 365 EINGNSVLGLDVEAVAQRLRGRAGTTVEVKLLDGTG 472 EING S + A A L G V + L GTG Sbjct: 1188 EINGESTRDM-THARAIELIKSGGRRVRLLLKRGTG 1222 Score = 31.6 bits (70), Expect = 1.8 Identities = 35/114 (30%), Positives = 53/114 (46%), Gaps = 20/114 (17%) Frame = +2 Query: 185 SQRSSPPRNIMSFKIGSDG-NLQGVGIFINR------------DPATGRLLVMNCIDGGP 325 S++ PPR SF++ S G + + + + + R D +L+ I G Sbjct: 754 SRQQVPPRT--SFRMDSSGPDYKELDVHLRRMESGFGFRILGGDEPGQPILIGAVIAMGS 811 Query: 326 ADRAG-IHEGDELVEINGNSVLG------LDVEAVAQRLRGRAGTTVEVKLLDG 466 ADR G +H GDELV ++G V G +D+ A R G+ TV K+L G Sbjct: 812 ADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAAR-NGQVNLTVRRKVLCG 864
>CSKP_MOUSE (O70589) Peripheral plasma membrane protein CASK (EC 2.7.11.1)| (Calcium/calmodulin-dependent serine protein kinase) Length = 924 Score = 33.9 bits (76), Expect = 0.36 Identities = 20/49 (40%), Positives = 27/49 (55%), Gaps = 1/49 (2%) Frame = +2 Query: 296 LVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQRLRGRAGT 439 +V + GG R G +H GDE+ EING SV VE + + LR G+ Sbjct: 514 IVARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGS 562
>CSKP_RAT (Q62915) Peripheral plasma membrane protein CASK (EC 2.7.11.1)| (Calcium/calmodulin-dependent serine protein kinase) Length = 909 Score = 33.9 bits (76), Expect = 0.36 Identities = 20/49 (40%), Positives = 27/49 (55%), Gaps = 1/49 (2%) Frame = +2 Query: 296 LVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQRLRGRAGT 439 +V + GG R G +H GDE+ EING SV VE + + LR G+ Sbjct: 514 IVARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGS 562
>RPGF2_HUMAN (Q9Y4G8) Rap guanine nucleotide exchange factor 2 (Neural RAP| guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF) Length = 1499 Score = 33.9 bits (76), Expect = 0.36 Identities = 18/72 (25%), Positives = 34/72 (47%) Frame = +2 Query: 239 GNLQGVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQR 418 G+ +G GIF++ + G A AG+ GD+++E+NG + + + + Sbjct: 404 GSEKGFGIFVD-----------SVDSGSKATEAGLKRGDQILEVNGQNFENIQLSKAMEI 452 Query: 419 LRGRAGTTVEVK 454 LR ++ VK Sbjct: 453 LRNNTHLSITVK 464
>DEGP_BARHE (P54925) Probable periplasmic serine protease DO-like precursor (EC| 3.4.21.-) (Antigen htrA) Length = 503 Score = 33.9 bits (76), Expect = 0.36 Identities = 22/66 (33%), Positives = 38/66 (57%), Gaps = 1/66 (1%) Frame = +2 Query: 320 GPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRA-GTTVEVKLLDGTGIERSGRIK 496 GPA +AGI GD ++ +NG + DV +A+R+ + G TV + G+ +SG+ + Sbjct: 333 GPAAKAGIKAGDVIISVNGEKI--NDVRDLAKRIANMSPGETVTL------GVWKSGKEE 384 Query: 497 QKEVQL 514 +V+L Sbjct: 385 NIKVKL 390
>CSKP_HUMAN (O14936) Peripheral plasma membrane protein CASK (EC 2.7.11.1)| (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog) Length = 926 Score = 33.9 bits (76), Expect = 0.36 Identities = 20/49 (40%), Positives = 27/49 (55%), Gaps = 1/49 (2%) Frame = +2 Query: 296 LVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQRLRGRAGT 439 +V + GG R G +H GDE+ EING SV VE + + LR G+ Sbjct: 514 IVARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGS 562
>WHRN_HUMAN (Q9P202) Whirlin (Autosomal recessive deafness type 31 protein)| Length = 907 Score = 33.9 bits (76), Expect = 0.36 Identities = 25/105 (23%), Positives = 47/105 (44%), Gaps = 9/105 (8%) Frame = +2 Query: 167 PR*GTLSQRSSPPRNIMSFKIGSD--------GNLQGVGIFINRDPATGRLLVMNCID-G 319 P G L Q+ R+ + G D G+ + +G+ I G + + +D G Sbjct: 253 PHGGALRQQEGDRRSTLHLLQGGDEKKVNLVLGDGRSLGLTIRGGAEYGLGIYITGVDPG 312 Query: 320 GPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVK 454 A+ +G+ GD+++E+NG S L + + + L+ + VK Sbjct: 313 SEAEGSGLKVGDQILEVNGRSFLNILHDEAVRLLKSSRHLILTVK 357
>TX1B3_MOUSE (Q9DBG9) Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1)| Length = 124 Score = 33.9 bits (76), Expect = 0.36 Identities = 20/80 (25%), Positives = 38/80 (47%) Frame = +2 Query: 212 IMSFKIGSDGNLQGVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSVLG 391 I+ F IG + + D + V +GGPA+ AG+ GD+++++NG + Sbjct: 28 ILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAGLQIGDKIMQVNGWDMTM 87 Query: 392 LDVEAVAQRLRGRAGTTVEV 451 + + +RL R+ V + Sbjct: 88 VTHDQARKRLTKRSEEVVRL 107
>TX1B3_HUMAN (O14907) Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1)| (Glutaminase-interacting protein 3) Length = 124 Score = 33.9 bits (76), Expect = 0.36 Identities = 20/80 (25%), Positives = 38/80 (47%) Frame = +2 Query: 212 IMSFKIGSDGNLQGVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSVLG 391 I+ F IG + + D + V +GGPA+ AG+ GD+++++NG + Sbjct: 28 ILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAGLQIGDKIMQVNGWDMTM 87 Query: 392 LDVEAVAQRLRGRAGTTVEV 451 + + +RL R+ V + Sbjct: 88 VTHDQARKRLTKRSEEVVRL 107
>MAGI2_HUMAN (Q86UL8) Membrane-associated guanylate kinase, WW and PDZ| domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A) Length = 1455 Score = 33.9 bits (76), Expect = 0.36 Identities = 28/108 (25%), Positives = 52/108 (48%), Gaps = 16/108 (14%) Frame = +2 Query: 185 SQRSSPPRNIMSFKIGSDGNL------QGVGIFI----NRDPATGRLLVM-----NCIDG 319 S +SPP S + + + +G G I NR P +G + + IDG Sbjct: 902 SSNASPPEGFASHSLQTSDVVIHRKENEGFGFVIISSLNR-PESGSTITVPHKIGRIIDG 960 Query: 320 GPADR-AGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLL 460 PADR A + GD ++ +NG S++ + + + ++ AG +V ++++ Sbjct: 961 SPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKD-AGLSVTLRII 1007 Score = 33.1 bits (74), Expect = 0.62 Identities = 30/96 (31%), Positives = 43/96 (44%), Gaps = 6/96 (6%) Frame = +2 Query: 203 PRNIMSFKIGSDGNLQGVGIFINRDPATGR-----LLVMNCIDGGPADRAG-IHEGDELV 364 P++ F + + +G G I GR L V+ + GPA R G + GD+++ Sbjct: 1140 PQDFDYFTVDMEKGAKGFGFSIRG----GREYKMDLYVLRLAEDGPAIRNGRMRVGDQII 1195 Query: 365 EINGNSVLGLDVEAVAQRLRGRAGTTVEVKLLDGTG 472 EING S + A A L G V + L GTG Sbjct: 1196 EINGESTRDM-THARAIELIKSGGRRVRLLLKRGTG 1230 Score = 31.6 bits (70), Expect = 1.8 Identities = 35/114 (30%), Positives = 53/114 (46%), Gaps = 20/114 (17%) Frame = +2 Query: 185 SQRSSPPRNIMSFKIGSDG-NLQGVGIFINR------------DPATGRLLVMNCIDGGP 325 S++ PPR SF++ S G + + + + + R D +L+ I G Sbjct: 755 SRQQVPPRT--SFRMDSSGPDYKELDVHLRRMESGFGFRILGGDEPGQPILIGAVIAMGS 812 Query: 326 ADRAG-IHEGDELVEINGNSVLG------LDVEAVAQRLRGRAGTTVEVKLLDG 466 ADR G +H GDELV ++G V G +D+ A R G+ TV K+L G Sbjct: 813 ADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAAR-NGQVNLTVRRKVLCG 865
>MUC1_YEAST (P08640) Mucin-like protein 1 precursor| Length = 1367 Score = 27.7 bits (60), Expect(2) = 0.40 Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 1/81 (1%) Frame = -2 Query: 474 IPVPSNSFT-STVVPARPLSL*ATASTSNPKTLFPLISTSSSPSCMPALSAGPPSMQFIT 298 +P PS+S T S+ PA S T S+S P T +T SS + +P P S + Sbjct: 512 VPTPSSSTTESSSAPAPTPSSSTTESSSAPVT---SSTTESSSAPVPT----PSSSTTES 564 Query: 297 SKRPVAGSLFMNMPTPCKFPS 235 S PV S + P PS Sbjct: 565 SSTPVTSSTTESSSAPVPTPS 585 Score = 26.2 bits (56), Expect(2) = 2.3 Identities = 25/80 (31%), Positives = 36/80 (45%) Frame = -2 Query: 474 IPVPSNSFTSTVVPARPLSL*ATASTSNPKTLFPLISTSSSPSCMPALSAGPPSMQFITS 295 +P PS+S T + + P++ T S+S P P ST+ S S A + P S +S Sbjct: 485 VPTPSSSTTES--SSAPVTSSTTESSSAPVPT-PSSSTTESSS---APAPTPSSSTTESS 538 Query: 294 KRPVAGSLFMNMPTPCKFPS 235 PV S + P PS Sbjct: 539 SAPVTSSTTESSSAPVPTPS 558 Score = 24.6 bits (52), Expect(2) = 0.40 Identities = 16/59 (27%), Positives = 23/59 (38%) Frame = -1 Query: 253 PLQIPIASDLETHDIPWG**SL*KGPLAWTPXXXXXXXXRLPISAGTSPPSSAEVSGPS 77 P+ P +S E+ P A TP P+++ T+ SSA V PS Sbjct: 595 PVPTPSSSTTESSSAP-----------APTPSSSTTESSSAPVTSSTTESSSAPVPTPS 642 Score = 23.5 bits (49), Expect(2) = 2.3 Identities = 10/30 (33%), Positives = 14/30 (46%) Frame = -1 Query: 166 TPXXXXXXXXRLPISAGTSPPSSAEVSGPS 77 TP P+++ T+ SSA V PS Sbjct: 556 TPSSSTTESSSTPVTSSTTESSSAPVPTPS 585
>Y1582_MYCLE (Q9CBU4) Hypothetical zinc metalloprotease ML1582 (EC 3.4.24.-)| Length = 404 Score = 33.5 bits (75), Expect = 0.47 Identities = 22/58 (37%), Positives = 29/58 (50%), Gaps = 1/58 (1%) Frame = +2 Query: 305 NCIDGGPADRAGIHEGDELVEINGNSVLGL-DVEAVAQRLRGRAGTTVEVKLLDGTGI 475 NC GPA AG+ GD +V+I +V D+ AV ++L G E DGT I Sbjct: 152 NCTGPGPAALAGLRAGDVVVKIGDTTVSTFDDMAAVVRKLHGTVPIVFE---RDGTAI 206
>LIN7B_RAT (Q9Z252) LIN-7 homolog B (LIN-7B) (Mammalian LIN-seven protein 2)| (MALS-2) (Vertebrate LIN 7 homolog 2) (Veli-2 protein) Length = 207 Score = 33.5 bits (75), Expect = 0.47 Identities = 18/50 (36%), Positives = 27/50 (54%), Gaps = 1/50 (2%) Frame = +2 Query: 293 LLVMNCIDGGPADR-AGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGT 439 + + I GG ADR G+ GD+L+ +NG SV G E + L+ G+ Sbjct: 117 IYISRVIPGGVADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGS 166
>LIN7B_MOUSE (O88951) LIN-7 homolog B (LIN-7B) (Mammalian LIN-seven protein 2)| (MALS-2) (Vertebrate LIN 7 homolog 2) (Veli-2 protein) Length = 207 Score = 33.5 bits (75), Expect = 0.47 Identities = 18/50 (36%), Positives = 27/50 (54%), Gaps = 1/50 (2%) Frame = +2 Query: 293 LLVMNCIDGGPADR-AGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGT 439 + + I GG ADR G+ GD+L+ +NG SV G E + L+ G+ Sbjct: 117 IYISRVIPGGVADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGS 166
>PARD3_HUMAN (Q8TEW0) Partitioning-defective 3 homolog (PARD-3) (PAR-3)| (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2-5) (PAR3-alpha) Length = 1356 Score = 33.5 bits (75), Expect = 0.47 Identities = 32/116 (27%), Positives = 49/116 (42%), Gaps = 20/116 (17%) Frame = +2 Query: 137 PPTARSAGWCPR*GTLSQRSSPPRNIMSFKIGSDGNLQGVGIFIN--------------- 271 P +A +G P S +S P+N+ S + S N + +G +N Sbjct: 422 PHSAHPSGKPP-----SAPASAPQNVFSTTVSSGYNTKKIGKRLNIQLKKGTEGLGFSIT 476 Query: 272 -RDPATGR---LLVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQRLR 424 RD G + V N + G A + G + GD L+E+NG ++G E V LR Sbjct: 477 SRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLVGKSQEEVVSLLR 532 Score = 32.3 bits (72), Expect = 1.1 Identities = 22/85 (25%), Positives = 42/85 (49%), Gaps = 7/85 (8%) Frame = +2 Query: 206 RNIMSFKIG-SDGNLQGVGIFIN-----RDPATGRLLVMNCIDGGPADRAG-IHEGDELV 364 R ++F++ +D G+G+ + + A + V + I+GG A + G + D+L+ Sbjct: 584 REFLTFEVPLNDSGSAGLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQLI 643 Query: 365 EINGNSVLGLDVEAVAQRLRGRAGT 439 +NG S+LG + + LR T Sbjct: 644 AVNGESLLGKTNQDAMETLRRSMST 668
>LIN7C_RAT (Q792I0) LIN-7 homolog C (LIN-7C) (Mammalian LIN-seven protein 3)| (MALS-3) (Vertebrate LIN 7 homolog 3) (Veli-3 protein) Length = 197 Score = 33.1 bits (74), Expect = 0.62 Identities = 21/57 (36%), Positives = 31/57 (54%), Gaps = 1/57 (1%) Frame = +2 Query: 293 LLVMNCIDGGPADR-AGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLL 460 + + I GG ADR G+ GD+L+ +NG SV G E + L+ G +VKL+ Sbjct: 117 IYISRIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQG---KVKLV 170
>LIN7C_MOUSE (O88952) LIN-7 homolog C (LIN-7C) (mLin7C) (Mammalian LIN-seven| protein 3) (MALS-3) (Vertebrate LIN 7 homolog 3) (Veli-3 protein) Length = 197 Score = 33.1 bits (74), Expect = 0.62 Identities = 21/57 (36%), Positives = 31/57 (54%), Gaps = 1/57 (1%) Frame = +2 Query: 293 LLVMNCIDGGPADR-AGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLL 460 + + I GG ADR G+ GD+L+ +NG SV G E + L+ G +VKL+ Sbjct: 117 IYISRIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQG---KVKLV 170
>LIN7C_HUMAN (Q9NUP9) LIN-7 homolog C (LIN-7C) (Mammalian LIN-seven protein 3)| (MALS-3) (Vertebrate LIN 7 homolog 3) (Veli-3 protein) Length = 197 Score = 33.1 bits (74), Expect = 0.62 Identities = 21/57 (36%), Positives = 31/57 (54%), Gaps = 1/57 (1%) Frame = +2 Query: 293 LLVMNCIDGGPADR-AGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLL 460 + + I GG ADR G+ GD+L+ +NG SV G E + L+ G +VKL+ Sbjct: 117 IYISRIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQG---KVKLV 170
>GRIP1_MOUSE (Q925T6) Glutamate receptor-interacting protein 1 (GRIP1 protein)| Length = 1127 Score = 33.1 bits (74), Expect = 0.62 Identities = 21/70 (30%), Positives = 37/70 (52%), Gaps = 1/70 (1%) Frame = +2 Query: 293 LLVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLLDGT 469 +++ + GG A+R G IH GD ++ IN +S+ G + L+ AG TV +K+ T Sbjct: 696 IIISSLTKGGLAERTGAIHIGDRILAINSSSLKGKPLSEAIHLLQ-MAGETVTLKIKKQT 754 Query: 470 GIERSGRIKQ 499 + + K+ Sbjct: 755 DAQSASSPKK 764
>MPP2_MOUSE (Q9WV34) MAGUK p55 subfamily member 2 (MPP2 protein) (Dlgh2| protein) Length = 552 Score = 33.1 bits (74), Expect = 0.62 Identities = 18/54 (33%), Positives = 30/54 (55%), Gaps = 1/54 (1%) Frame = +2 Query: 287 GRLLVMNCIDGGPADRAGI-HEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTV 445 G L++ + GG + G+ H GD + E+NG V G D A+ + LR +G+ + Sbjct: 160 GELVIARILHGGMVAQQGLLHVGDIIKEVNGQPV-GSDPRALQELLRSASGSVI 212
>GRIP1_HUMAN (Q9Y3R0) Glutamate receptor-interacting protein 1 (GRIP1 protein)| Length = 1128 Score = 33.1 bits (74), Expect = 0.62 Identities = 21/70 (30%), Positives = 37/70 (52%), Gaps = 1/70 (1%) Frame = +2 Query: 293 LLVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLLDGT 469 +++ + GG A+R G IH GD ++ IN +S+ G + L+ AG TV +K+ T Sbjct: 697 IIISSLTKGGLAERTGAIHIGDRILAINSSSLKGKPLSEAIHLLQ-MAGETVTLKIKKQT 755 Query: 470 GIERSGRIKQ 499 + + K+ Sbjct: 756 DAQSASSPKK 765
>PTN13_MOUSE (Q64512) Tyrosine-protein phosphatase non-receptor type 13 (EC| 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36) Length = 2453 Score = 33.1 bits (74), Expect = 0.62 Identities = 29/97 (29%), Positives = 49/97 (50%), Gaps = 6/97 (6%) Frame = +2 Query: 194 SSPPRNIMSFKIG---SDGNLQGVGIF--INRDPATGRLLVMNCIDGGPADRAG-IHEGD 355 +SPP+ +F++ +DG+L G+ + +N G + V I G A+ G IH+GD Sbjct: 1347 ASPPKPGDTFEVELAKTDGSL-GISVTGGVNTSVRHGGIYVKAIIPKGAAESDGRIHKGD 1405 Query: 356 ELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLLDG 466 ++ +NG S+ G + + LR G V + L G Sbjct: 1406 RVLAVNGVSLEGATHKQAVETLR-NTGQVVHLLLEKG 1441 Score = 30.8 bits (68), Expect = 3.1 Identities = 27/89 (30%), Positives = 42/89 (47%), Gaps = 8/89 (8%) Frame = +2 Query: 218 SFKIGSDGNLQGVGIFINRDP------ATGRLL-VMNCIDGGPADRAG-IHEGDELVEIN 373 +F++ N G+G +R+ G ++ V G PA +G I GD ++++N Sbjct: 1489 TFEVKLFKNSSGLGFSFSREDNLIPEQINGSIVRVKKLFPGQPAAESGKIDVGDVILKVN 1548 Query: 374 GNSVLGLDVEAVAQRLRGRAGTTVEVKLL 460 G + GL + V LR GT EV LL Sbjct: 1549 GAPLKGLSQQDVISALR---GTAPEVSLL 1574
>MPP2_HUMAN (Q14168) MAGUK p55 subfamily member 2 (MPP2 protein) (Discs large| homolog 2) Length = 576 Score = 33.1 bits (74), Expect = 0.62 Identities = 18/54 (33%), Positives = 30/54 (55%), Gaps = 1/54 (1%) Frame = +2 Query: 287 GRLLVMNCIDGGPADRAGI-HEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTV 445 G L++ + GG + G+ H GD + E+NG V G D A+ + LR +G+ + Sbjct: 184 GELVIARILHGGMVAQQGLLHVGDIIKEVNGQPV-GSDPRALQELLRNASGSVI 236
>WHRN_MOUSE (Q80VW5) Whirlin| Length = 906 Score = 33.1 bits (74), Expect = 0.62 Identities = 25/105 (23%), Positives = 46/105 (43%), Gaps = 9/105 (8%) Frame = +2 Query: 167 PR*GTLSQRSSPPRNIMSFKIGSD--------GNLQGVGIFINRDPATGRLLVMNCID-G 319 P TL QR R+ + D G+ + +G+ I G + + +D G Sbjct: 254 PHGSTLRQREDDRRSTLHLLQSGDEKKVNLVLGDGRSLGLTIRGGAEYGLGIYITGVDPG 313 Query: 320 GPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVK 454 A+ +G+ GD+++E+NG S L + + + L+ + VK Sbjct: 314 SEAESSGLKVGDQILEVNGRSFLNILHDEAVKLLKSSRHLILTVK 358
>GRIP1_RAT (P97879) Glutamate receptor-interacting protein 1 (GRIP1 protein)| (AMPA receptor-interacting protein GRIP1) Length = 1112 Score = 32.7 bits (73), Expect = 0.81 Identities = 21/70 (30%), Positives = 37/70 (52%), Gaps = 1/70 (1%) Frame = +2 Query: 293 LLVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLLDGT 469 +++ + GG A+R G IH GD ++ IN +S+ G + L+ AG TV +K+ T Sbjct: 696 IIISSLTKGGLAERTGAIHIGDRILAINSSSLKGKPLSEAIHLLQ-MAGETVTLKIKKQT 754 Query: 470 GIERSGRIKQ 499 + + K+ Sbjct: 755 DAQPASSPKK 764
>RHPN1_MOUSE (Q61085) Rhophilin-1 (GTP-Rho-binding protein 1)| Length = 643 Score = 32.7 bits (73), Expect = 0.81 Identities = 24/72 (33%), Positives = 36/72 (50%), Gaps = 8/72 (11%) Frame = +2 Query: 293 LLVMNCIDGGPADRAGIHEGDELVEINGNSV-LGLDVEAVAQ-RLRGRAGTTVEVKLL-- 460 +L+ + GG A+ AG+ EGD +V +NG +E V Q R G G +++V L Sbjct: 520 VLIAAVVPGGQAESAGLKEGDYIVSVNGQPCKWWKHLEVVTQLRSMGEEGVSLQVVSLLP 579 Query: 461 ----DGTGIERS 484 GTG R+ Sbjct: 580 SPEPRGTGPRRA 591
>PAR3L_HUMAN (Q8TEW8) Amyotrophic lateral sclerosis 2 chromosome region| candidate gene 19 protein (Partitioning-defective 3-like protein) (PAR3-L protein) (PAR3-beta) Length = 1205 Score = 32.7 bits (73), Expect = 0.81 Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 5/78 (6%) Frame = +2 Query: 206 RNIMSFKIGSDGNLQGVGI-FINRDPAT---GRLLVMNCIDGGPADRAG-IHEGDELVEI 370 +N KI +G+G + RD + G + V N + G A + G + GD ++E+ Sbjct: 377 KNAKKIKIDLKKGPEGLGFTVVTRDSSIHGPGPIFVKNILPKGAAIKDGRLQSGDRILEV 436 Query: 371 NGNSVLGLDVEAVAQRLR 424 NG V G E + LR Sbjct: 437 NGRDVTGRTQEELVAMLR 454 Score = 30.8 bits (68), Expect = 3.1 Identities = 20/70 (28%), Positives = 35/70 (50%), Gaps = 6/70 (8%) Frame = +2 Query: 233 SDGNLQGVGIFI--NRDPATGR---LLVMNCIDGGPADRAG-IHEGDELVEINGNSVLGL 394 +D G+G+ + N+ TG + + + I GG A + G + D+L+ +NG S+LG Sbjct: 502 NDSGSAGLGVSLKGNKSRETGTDLGIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGK 561 Query: 395 DVEAVAQRLR 424 + LR Sbjct: 562 SNHEAMETLR 571
>SYA_MYCLE (Q9CCT0) Alanyl-tRNA synthetase (EC 6.1.1.7) (Alanine--tRNA ligase)| (AlaRS) Length = 908 Score = 32.7 bits (73), Expect = 0.81 Identities = 25/64 (39%), Positives = 32/64 (50%), Gaps = 3/64 (4%) Frame = +2 Query: 311 IDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKL-LDGTGI--ER 481 +D GP + G E I G V G V VA +RG+AG T V+L LD T + E Sbjct: 462 VDAGPTEFTGFDELTTEARILGIFVEGKRVPVVAHAVRGQAGITNRVELVLDRTPLYAES 521 Query: 482 SGRI 493 G+I Sbjct: 522 GGQI 525
>RPGF2_MOUSE (Q8CHG7) Rap guanine nucleotide exchange factor 2 (Neural RAP| guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (Fragment) Length = 1138 Score = 32.3 bits (72), Expect = 1.1 Identities = 19/72 (26%), Positives = 35/72 (48%) Frame = +2 Query: 239 GNLQGVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQR 418 G+ +G GIF++ V +C A AG+ GD+++E+NG + + + + Sbjct: 46 GSEKGFGIFVDS--------VDSC---SKATEAGLKRGDQILEVNGQNFENIQLSKAMEI 94 Query: 419 LRGRAGTTVEVK 454 LR ++ VK Sbjct: 95 LRNNTHLSITVK 106
>DEGP_CHLTR (P18584) Probable serine protease do-like precursor (EC 3.4.21.-)| (59 kDa immunogenic protein) (SK59) Length = 497 Score = 32.3 bits (72), Expect = 1.1 Identities = 22/62 (35%), Positives = 33/62 (53%), Gaps = 1/62 (1%) Frame = +2 Query: 296 LVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLL-DGTG 472 LV + + G PA++AG+ + D +V NG V L A L GT V +K++ +G Sbjct: 326 LVTDVVKGSPAEKAGLRQEDVIVAYNGKEVESLSALRNAISLM-MPGTRVVLKIVREGKT 384 Query: 473 IE 478 IE Sbjct: 385 IE 386
>CAKI_DROME (Q24210) Calcium/calmodulin-dependent protein kinase (EC 2.7.11.17)| (CAKI) (Peripheral plasma membrane protein CaMGUK) Length = 898 Score = 32.3 bits (72), Expect = 1.1 Identities = 20/52 (38%), Positives = 27/52 (51%), Gaps = 1/52 (1%) Frame = +2 Query: 287 GRLLVMNCIDGGPADR-AGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGT 439 GR +V + GG R A +H GDE+ EING V V + + LR G+ Sbjct: 516 GRCIVARIMHGGMIHRQATLHVGDEIREINGQPVQHQSVGQLQRMLREARGS 567
>PARD3_RAT (Q9Z340) Partitioning-defective 3 homolog (PARD-3) (PAR-3)| (Atypical PKC isotype-specific-interacting protein) (ASIP) (Atypical PKC-specific-binding protein) (ASBP) Length = 1337 Score = 32.3 bits (72), Expect = 1.1 Identities = 22/85 (25%), Positives = 42/85 (49%), Gaps = 7/85 (8%) Frame = +2 Query: 206 RNIMSFKIG-SDGNLQGVGIFIN-----RDPATGRLLVMNCIDGGPADRAG-IHEGDELV 364 R ++F++ +D G+G+ + + A + V + I+GG A + G + D+L+ Sbjct: 584 REFLTFEVPLNDSGSAGLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQLI 643 Query: 365 EINGNSVLGLDVEAVAQRLRGRAGT 439 +NG S+LG + + LR T Sbjct: 644 AVNGESLLGKANQEAMETLRRSMST 668 Score = 32.3 bits (72), Expect = 1.1 Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 20/94 (21%) Frame = +2 Query: 203 PRNIMSFKIGSDGNLQGVGIFIN----------------RDPATGR---LLVMNCIDGGP 325 P N++S +GS N + VG +N RD G + V N + G Sbjct: 439 PPNVLSTSVGSVYNTKRVGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPRGA 498 Query: 326 ADRAG-IHEGDELVEINGNSVLGLDVEAVAQRLR 424 A + G + GD L+E+NG + G E V LR Sbjct: 499 AIQDGRLKAGDRLIEVNGVDLAGKSQEEVVSLLR 532
>Y3649_PSEAE (Q9HXY3) Hypothetical zinc metalloprotease PA3649 (EC 3.4.24.-)| Length = 450 Score = 32.3 bits (72), Expect = 1.1 Identities = 19/47 (40%), Positives = 27/47 (57%) Frame = +2 Query: 320 GPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLL 460 GPA AG+ GD L I+G +V D + V +R R G V++K+L Sbjct: 233 GPAQAAGLKLGDRLQSIDGIAV--DDWQQVVDSVRARPGQRVQLKVL 277
>ZO3_HUMAN (O95049) Tight junction protein ZO-3 (Zonula occludens 3 protein)| (Zona occludens 3 protein) (Tight junction protein 3) Length = 933 Score = 32.3 bits (72), Expect = 1.1 Identities = 25/82 (30%), Positives = 35/82 (42%), Gaps = 5/82 (6%) Frame = +2 Query: 197 SPPRNIMSFKIGSDGNLQ-----GVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDEL 361 SP ++ F G L+ VGIF++ A G PAD GI EGD++ Sbjct: 392 SPDTRVVRFLKGKSIGLRLAGGNDVGIFVSGVQA-----------GSPADGQGIQEGDQI 440 Query: 362 VEINGNSVLGLDVEAVAQRLRG 427 +++N L E Q L G Sbjct: 441 LQVNDVPFQNLTREEAVQFLLG 462
>LIMK2_MOUSE (O54785) LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2)| Length = 638 Score = 32.3 bits (72), Expect = 1.1 Identities = 16/39 (41%), Positives = 22/39 (56%) Frame = +2 Query: 323 PADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGT 439 P +R IH GD ++EING V L VE V ++ + T Sbjct: 192 PNNRNAIHPGDRILEINGTPVRTLRVEEVEDAIKQTSQT 230
>DEGP_RHIME (Q52894) Probable serine protease do-like precursor (EC 3.4.21.-)| Length = 504 Score = 32.3 bits (72), Expect = 1.1 Identities = 21/55 (38%), Positives = 30/55 (54%), Gaps = 1/55 (1%) Frame = +2 Query: 296 LVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRG-RAGTTVEVKL 457 LV+ G P ++AGI GD + +NG V D +A+R+ R G+T EV L Sbjct: 323 LVVEPQAGSPGEKAGIKNGDVVTALNGEPV--KDPRDLARRVAALRPGSTAEVTL 375
>PARD3_MOUSE (Q99NH2) Partitioning-defective 3 homolog (PARD-3) (PAR-3)| (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP) Length = 1333 Score = 32.3 bits (72), Expect = 1.1 Identities = 22/85 (25%), Positives = 42/85 (49%), Gaps = 7/85 (8%) Frame = +2 Query: 206 RNIMSFKIG-SDGNLQGVGIFIN-----RDPATGRLLVMNCIDGGPADRAG-IHEGDELV 364 R ++F++ +D G+G+ + + A + V + I+GG A + G + D+L+ Sbjct: 584 REFLTFEVPLNDSGSAGLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQLI 643 Query: 365 EINGNSVLGLDVEAVAQRLRGRAGT 439 +NG S+LG + + LR T Sbjct: 644 AVNGESLLGKANQEAMETLRRSMST 668 Score = 30.4 bits (67), Expect = 4.0 Identities = 27/94 (28%), Positives = 40/94 (42%), Gaps = 20/94 (21%) Frame = +2 Query: 203 PRNIMSFKIGSDGNLQGVGIFIN----------------RDPATGR---LLVMNCIDGGP 325 P +++S +GS N + VG +N RD G + V N + G Sbjct: 439 PPSVLSTNVGSVYNTKKVGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPRGA 498 Query: 326 ADRAG-IHEGDELVEINGNSVLGLDVEAVAQRLR 424 A + G + GD L+E+NG + G E V LR Sbjct: 499 AIQDGRLKAGDRLIEVNGVDLAGKSQEEVVSLLR 532
>PAR6_CAEEL (Q9NAN2) Partitioning defective protein 6| Length = 309 Score = 32.3 bits (72), Expect = 1.1 Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 1/77 (1%) Frame = +2 Query: 206 RNIMSFKIGSDGNLQGVGIFINRDPATGRLLVMNCIDGGPADRAGI-HEGDELVEINGNS 382 R+ S ++ G ++ GIFI+R +DGG A+ G+ DE++E+NG Sbjct: 173 RDGTSVRVTERGVVKVSGIFISR-----------LVDGGLAESTGLLGVNDEVLEVNGIE 221 Query: 383 VLGLDVEAVAQRLRGRA 433 VLG ++ V + A Sbjct: 222 VLGKTLDQVTDMMVANA 238
>ARHGB_RAT (Q9ES67) Rho guanine nucleotide exchange factor 11 (RhoGEF| glutamate transport modulator GTRAP48) Length = 1527 Score = 32.3 bits (72), Expect = 1.1 Identities = 13/31 (41%), Positives = 21/31 (67%) Frame = +2 Query: 293 LLVMNCIDGGPADRAGIHEGDELVEINGNSV 385 +LV + GG A +AG+ EGD ++++NG V Sbjct: 84 VLVQSVRPGGAAMKAGVKEGDRIIKVNGTMV 114
>ARHGB_HUMAN (O15085) Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF)| Length = 1522 Score = 32.3 bits (72), Expect = 1.1 Identities = 13/31 (41%), Positives = 21/31 (67%) Frame = +2 Query: 293 LLVMNCIDGGPADRAGIHEGDELVEINGNSV 385 +LV + GG A +AG+ EGD ++++NG V Sbjct: 67 VLVQSVRPGGAAMKAGVKEGDRIIKVNGTMV 97
>PDZK7_PONPY (Q5RBI7) PDZ domain-containing protein 7| Length = 528 Score = 32.0 bits (71), Expect = 1.4 Identities = 18/63 (28%), Positives = 33/63 (52%) Frame = +2 Query: 239 GNLQGVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQR 418 G+ G+GIF+++ +G A+RAG+ GD++ E+NG S+ + + + Sbjct: 104 GSEHGLGIFVSKVE-----------EGSSAERAGLCVGDKITEVNGLSLESTTMGSAVKV 152 Query: 419 LRG 427 L G Sbjct: 153 LTG 155
>PMS1_SCHPO (P54280) DNA mismatch repair protein pms1| Length = 794 Score = 32.0 bits (71), Expect = 1.4 Identities = 22/91 (24%), Positives = 38/91 (41%) Frame = -2 Query: 489 LPLLSIPVPSNSFTSTVVPARPLSL*ATASTSNPKTLFPLISTSSSPSCMPALSAGPPSM 310 L +S P+P ++ + PL+ TAS+ K L ++S+ S + + P Sbjct: 412 LAQVSKPLPERLQKDSMRRSSPLNEKVTASSERMKKKLALFASSTDTSMQKTIDSSFPLK 471 Query: 309 QFITSKRPVAGSLFMNMPTPCKFPSLPILKL 217 Q I +L +N P+P P + L Sbjct: 472 QPINKPSSNPNNLLLNDPSPASTPVAKTINL 502
>Y638_RHILO (Q98MC1) Hypothetical zinc metalloprotease mll0638 (EC 3.4.24.-)| Length = 367 Score = 31.6 bits (70), Expect = 1.8 Identities = 22/50 (44%), Positives = 28/50 (56%), Gaps = 2/50 (4%) Frame = +2 Query: 323 PADRAGIHEGDELVEINGNSVLGLDVEAVAQRL-RGRAGTTVE-VKLLDG 466 PA +AGI GD V ++G+ V + QRL GRAG T+ V L DG Sbjct: 149 PAAKAGIQPGDRFVSVDGSKV---ETFGDVQRLVSGRAGDTITFVMLRDG 195
>Y1318_LISMO (Q8Y7G3) Hypothetical zinc metalloprotease Lmo1318 (EC 3.4.24.-)| Length = 420 Score = 31.6 bits (70), Expect = 1.8 Identities = 20/69 (28%), Positives = 33/69 (47%) Frame = +2 Query: 305 NCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLLDGTGIERS 484 N + G A AG+ +GDE++ ING + Q + G T++ K IER Sbjct: 207 NVLPDGAAAEAGLKKGDEVLSINGKETKSW--TDIVQNVSENPGKTLDFK------IERD 258 Query: 485 GRIKQKEVQ 511 G+ + +V+ Sbjct: 259 GKTQDIDVK 267
>LIMK2_RAT (P53670) LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2)| Length = 638 Score = 31.6 bits (70), Expect = 1.8 Identities = 16/39 (41%), Positives = 21/39 (53%) Frame = +2 Query: 323 PADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGT 439 P +R IH GD ++EING V L VE V + + T Sbjct: 192 PNNRNAIHPGDRILEINGTPVRTLRVEEVEDAINQTSQT 230
>EM55_MOUSE (P70290) 55 kDa erythrocyte membrane protein (p55) (Membrane| protein, palmitoylated 1) (Palmytoylated protein p55) Length = 466 Score = 31.6 bits (70), Expect = 1.8 Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 1/47 (2%) Frame = +2 Query: 299 VMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQRLRGRAG 436 V + GG R G +H GDE++EING +V V+ + + ++ G Sbjct: 96 VARILHGGMIHRQGSLHVGDEILEINGTNVTNHSVDQLQKAMKETKG 142
>EM55_HUMAN (Q00013) 55 kDa erythrocyte membrane protein (p55) (Membrane| protein, palmitoylated 1) Length = 466 Score = 31.6 bits (70), Expect = 1.8 Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 1/47 (2%) Frame = +2 Query: 299 VMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQRLRGRAG 436 V + GG R G +H GDE++EING +V V+ + + ++ G Sbjct: 96 VARILHGGMIHRQGSLHVGDEILEINGTNVTNHSVDQLQKAMKETKG 142
>DLG1_BRARE (Q5PYH6) Disks large homolog 1 (Synapse-associated protein 97A)| (SAP-97A) Length = 873 Score = 31.6 bits (70), Expect = 1.8 Identities = 24/72 (33%), Positives = 33/72 (45%), Gaps = 1/72 (1%) Frame = +2 Query: 239 GNLQGVGIFINRDPATGRLLVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQ 415 G G GIFI+ + GGPAD G + +GD +V +NG + E A Sbjct: 490 GGEDGEGIFISF-----------ILAGGPADLCGELRKGDRIVSVNGVDLRSATHEQAAA 538 Query: 416 RLRGRAGTTVEV 451 L+ AG TV + Sbjct: 539 ALK-NAGQTVTI 549
>ZO3_CANFA (O62683) Tight junction protein ZO-3 (Zonula occludens 3 protein)| (Zona occludens 3 protein) (Tight junction protein 3) Length = 898 Score = 31.2 bits (69), Expect = 2.3 Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 5/80 (6%) Frame = +2 Query: 197 SPPRNIMSFKIGSDGNLQ-----GVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDEL 361 SP ++ F G+ L+ VGIF++ +G PAD GI EGD++ Sbjct: 367 SPDSRVVRFHKGTTIGLRLAGGNDVGIFVS-----------GVQEGSPADGQGIQEGDQI 415 Query: 362 VEINGNSVLGLDVEAVAQRL 421 +++N L E Q L Sbjct: 416 LQVNDVPFRNLTREEAVQFL 435
>Y2869_MYCTU (O33351) Hypothetical zinc metalloprotease Rv2869c/MT2937 (EC| 3.4.24.-) Length = 404 Score = 31.2 bits (69), Expect = 2.3 Identities = 21/56 (37%), Positives = 26/56 (46%) Frame = +2 Query: 308 CIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLLDGTGI 475 C GPA AGI GD +V++ V D A A +R G+ V DGT I Sbjct: 153 CTGPGPAALAGIRSGDVVVKVGDTPVSSFDEMAAA--VRKSHGSVPIVVERDGTAI 206
>PURL_THETN (Q8RBK5) Phosphoribosylformylglycinamidine synthase II (EC 6.3.5.3)| (FGAM synthase II) Length = 733 Score = 31.2 bits (69), Expect = 2.3 Identities = 13/37 (35%), Positives = 24/37 (64%), Gaps = 1/37 (2%) Frame = +2 Query: 323 PADRAGIHEGDELV-EINGNSVLGLDVEAVAQRLRGR 430 PA + G+ EG ++V ++NG ++ L +E + + RGR Sbjct: 689 PAQKVGVVEGKDIVIDVNGKRIIDLPLEVLEESWRGR 725
>FIBP_ADE31 (P36848) Fiber protein (pIV)| Length = 556 Score = 31.2 bits (69), Expect = 2.3 Identities = 29/90 (32%), Positives = 42/90 (46%), Gaps = 5/90 (5%) Frame = -2 Query: 471 PVPSNSFTSTVVPARPLSL*ATASTSNPKTLFPLISTSSSPSCMPALSAGPPSMQF---- 304 P+P S T+ + PLS+ A+A T N T+ P +T+ S S + A + Q Sbjct: 94 PLPHTSQGLTLSWSAPLSVKASALTLN--TMAPFTTTNESLSLVTAPPITVEASQLGLAS 151 Query: 303 -ITSKRPVAGSLFMNMPTPCKFPSLPILKL 217 TSK G+L ++P P PS L L Sbjct: 152 CSTSKLRGGGNLGFHLPAPFVVPSSNALTL 181
>DEGP_CHLMU (Q9PL97) Probable serine protease do-like precursor (EC 3.4.21.-)| Length = 497 Score = 31.2 bits (69), Expect = 2.3 Identities = 21/62 (33%), Positives = 33/62 (53%), Gaps = 1/62 (1%) Frame = +2 Query: 296 LVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLL-DGTG 472 L+ + + G PA++AG+ + D +V NG V L A L GT V +K++ +G Sbjct: 326 LITDVVKGSPAEKAGLRQEDVIVAYNGKEVESLSALRNAISLM-MPGTRVVLKVVREGKF 384 Query: 473 IE 478 IE Sbjct: 385 IE 386
>MAST1_MOUSE (Q9R1L5) Microtubule-associated serine/threonine-protein kinase 1 (EC| 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase) Length = 1566 Score = 31.2 bits (69), Expect = 2.3 Identities = 13/33 (39%), Positives = 20/33 (60%) Frame = +2 Query: 296 LVMNCIDGGPADRAGIHEGDELVEINGNSVLGL 394 +V + +GGPA AG+ GD + +NG V G+ Sbjct: 1000 IVWHVEEGGPAQEAGLCAGDLITHVNGEPVHGM 1032
>GRASP_RAT (Q8R4T5) General receptor for phosphoinositides 1-associated| scaffold protein (GRP1-associated scaffold protein) (Tamalin) (95 kDa postsynaptic density protein discs-large ZO-1 domain-containing protein) (PSD-95 PDZ domain-containing protein) Length = 394 Score = 31.2 bits (69), Expect = 2.3 Identities = 15/57 (26%), Positives = 30/57 (52%) Frame = +2 Query: 314 DGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLLDGTGIERS 484 + PA AG+ GD + +NG +V G+ + ++ +G + ++ L GT I ++ Sbjct: 139 ESSPAQLAGLTPGDTIASVNGLNVEGIRHREIVDIIKA-SGNVLRLETLYGTSIRKA 194
>WHRN_RAT (Q810W9) Whirlin (CASK-interacting protein CIP98)| Length = 920 Score = 31.2 bits (69), Expect = 2.3 Identities = 24/105 (22%), Positives = 45/105 (42%), Gaps = 9/105 (8%) Frame = +2 Query: 167 PR*GTLSQRSSPPRNIMSFKIGSD--------GNLQGVGIFINRDPATGRLLVMNCID-G 319 P TL Q R+ + D G+ + +G+ I G + + +D G Sbjct: 252 PHGSTLRQHEDDRRSALHLLQSGDEKKVNLVLGDGRSLGLTIRGGAEYGLGIYITGVDPG 311 Query: 320 GPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVK 454 A+ +G+ GD+++E+NG S L + + + L+ + VK Sbjct: 312 SEAESSGLKVGDQILEVNGRSFLSILHDEAVKLLKSSRHLILTVK 356
>GRASP_MOUSE (Q9JJA9) General receptor for phosphoinositides 1-associated| scaffold protein (GRP1-associated scaffold protein) Length = 392 Score = 31.2 bits (69), Expect = 2.3 Identities = 15/57 (26%), Positives = 30/57 (52%) Frame = +2 Query: 314 DGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLLDGTGIERS 484 + PA AG+ GD + +NG +V G+ + ++ +G + ++ L GT I ++ Sbjct: 139 ESSPAQLAGLTPGDTIASVNGLNVEGIRHREIVDIIKA-SGNVLRLETLYGTSIRKA 194
>MAGI1_MOUSE (Q6RHR9) Membrane-associated guanylate kinase, WW and PDZ| domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) Length = 1471 Score = 31.2 bits (69), Expect = 2.3 Identities = 19/61 (31%), Positives = 31/61 (50%), Gaps = 1/61 (1%) Frame = +2 Query: 293 LLVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLLDGT 469 L V+ + GPA+R G + GDE++EING + + + ++ G V + L G Sbjct: 1156 LYVLRLAEDGPAERCGKMRIGDEILEINGETTKNMKHSRAIELIK-NGGRRVRLFLRRGD 1214 Query: 470 G 472 G Sbjct: 1215 G 1215
>DEGP_CHLPN (Q9Z6T0) Probable serine protease do-like precursor (EC 3.4.21.-)| Length = 488 Score = 31.2 bits (69), Expect = 2.3 Identities = 13/35 (37%), Positives = 21/35 (60%) Frame = +2 Query: 296 LVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDV 400 LV + + G PAD+AG+ + D ++ NG V L + Sbjct: 317 LVTDVVKGSPADKAGLKQEDVIIAYNGKEVDSLSM 351
>MAGI1_HUMAN (Q96QZ7) Membrane-associated guanylate kinase, WW and PDZ| domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containi Length = 1491 Score = 31.2 bits (69), Expect = 2.3 Identities = 19/61 (31%), Positives = 31/61 (50%), Gaps = 1/61 (1%) Frame = +2 Query: 293 LLVMNCIDGGPADRAG-IHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLLDGT 469 L V+ + GPA+R G + GDE++EING + + + ++ G V + L G Sbjct: 1176 LYVLRLAEDGPAERCGKMRIGDEILEINGETTKNMKHSRAIELIK-NGGRRVRLFLKRGD 1234 Query: 470 G 472 G Sbjct: 1235 G 1235
>LIMK2_HUMAN (P53671) LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2)| Length = 638 Score = 31.2 bits (69), Expect = 2.3 Identities = 15/29 (51%), Positives = 18/29 (62%) Frame = +2 Query: 323 PADRAGIHEGDELVEINGNSVLGLDVEAV 409 P +R IH GD ++EING V L VE V Sbjct: 192 PNNRNAIHPGDRILEINGTPVRTLRVEEV 220
>GRASP_HUMAN (Q7Z6J2) General receptor for phosphoinositides 1-associated| scaffold protein (GRP1-associated scaffold protein) Length = 395 Score = 31.2 bits (69), Expect = 2.3 Identities = 15/57 (26%), Positives = 30/57 (52%) Frame = +2 Query: 314 DGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLLDGTGIERS 484 + PA AG+ GD + +NG +V G+ + ++ +G + ++ L GT I ++ Sbjct: 140 ESSPAQLAGLTPGDTIASVNGLNVEGIRHREIVDIIKA-SGNVLRLETLYGTSIRKA 195
>DSBD_VIBPA (Q87KW0) Thiol:disulfide interchange protein dsbD precursor (EC| 1.8.1.8) (Protein-disulfide reductase) (Disulfide reductase) Length = 613 Score = 31.2 bits (69), Expect = 2.3 Identities = 34/129 (26%), Positives = 52/129 (40%), Gaps = 9/129 (6%) Frame = -2 Query: 540 GERLITSRDSWTSFCFILPLLSIPVPSNSFTSTV----VPARPLSL*ATASTSNPKTLFP 373 G R+I F P + +P ++FT+++ V +P +TA+ + P Sbjct: 125 GARVIVQYQGCAKAGFCYPPETRIIPIDAFTASIADSAVATKPTQ--STANNNQTNATSP 182 Query: 372 LISTSSSPSCMPALSAGPPSMQFITSKRPVAGSLFMNMP-----TPCKFPSLPILKLMIF 208 STS S + PA S+ + LF+ + TPC P PIL I Sbjct: 183 TASTSVSSNNTPAPVTEQDSLAANLADNWWTPLLFLALGVGLAFTPCVLPMYPIL-TSIV 241 Query: 207 LGGDDLCER 181 LG L +R Sbjct: 242 LGSGKLSQR 250
>RLM1_YEAST (Q12224) Transcription factor RLM1| Length = 676 Score = 31.2 bits (69), Expect = 2.3 Identities = 19/66 (28%), Positives = 38/66 (57%), Gaps = 6/66 (9%) Frame = -2 Query: 486 PLLSIPVPSNSFTS-TVVPARPLSL*ATASTSNPKTLFPLI-----STSSSPSCMPALSA 325 P+L + +P+N+F+S + +P+ P S +T++ N ++ S SS S + A ++ Sbjct: 322 PVLRVRIPNNNFSSNSAIPSEPSSASSTSANGNSMGSSQIMKENKTSRSSKISPLSASAS 381 Query: 324 GPPSMQ 307 GP ++Q Sbjct: 382 GPLTLQ 387
>PDZK7_HUMAN (Q9H5P4) PDZ domain-containing protein 7| Length = 517 Score = 31.2 bits (69), Expect = 2.3 Identities = 16/49 (32%), Positives = 28/49 (57%) Frame = +2 Query: 239 GNLQGVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSV 385 G+ G+GIF+++ +G A+RAG+ GD++ E+NG S+ Sbjct: 104 GSEHGLGIFVSKVE-----------EGSSAERAGLCVGDKITEVNGLSL 141
>MAST1_RAT (Q810W7) Microtubule-associated serine/threonine-protein kinase 1 (EC| 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase) Length = 1570 Score = 31.2 bits (69), Expect = 2.3 Identities = 13/33 (39%), Positives = 20/33 (60%) Frame = +2 Query: 296 LVMNCIDGGPADRAGIHEGDELVEINGNSVLGL 394 +V + +GGPA AG+ GD + +NG V G+ Sbjct: 1001 IVWHVEEGGPAQEAGLCAGDLITHVNGEPVHGM 1033
>MAST1_HUMAN (Q9Y2H9) Microtubule-associated serine/threonine-protein kinase 1 (EC| 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase) Length = 1570 Score = 31.2 bits (69), Expect = 2.3 Identities = 13/33 (39%), Positives = 20/33 (60%) Frame = +2 Query: 296 LVMNCIDGGPADRAGIHEGDELVEINGNSVLGL 394 +V + +GGPA AG+ GD + +NG V G+ Sbjct: 999 IVWHVEEGGPAQEAGLCAGDLITHVNGEPVHGM 1031
>Y1693_CLOPE (Q8XJR2) Hypothetical zinc metalloprotease CPE1693 (EC 3.4.24.-)| Length = 335 Score = 30.8 bits (68), Expect = 3.1 Identities = 17/59 (28%), Positives = 29/59 (49%) Frame = +2 Query: 299 VMNCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLLDGTGI 475 V + + PA GI +GDE ++I+GN + D + L G VE+++ G + Sbjct: 120 VASVVPNSPAQEIGIEQGDEFLKIDGNKIHTTDDFRMGLAL--AKGNPVELEIKRGNDV 176
>RGS12_HUMAN (O14924) Regulator of G-protein signaling 12 (RGS12)| Length = 1447 Score = 30.8 bits (68), Expect = 3.1 Identities = 17/59 (28%), Positives = 32/59 (54%), Gaps = 1/59 (1%) Frame = +2 Query: 299 VMNCI-DGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLLDGTG 472 V++C+ G PAD G+ GD+++ +N +V E V +L G+ + + + +G G Sbjct: 43 VLSCVMRGSPADFVGLRAGDQILAVNEINVKKASHEDVV-KLIGKCSGVLHMVIAEGVG 100
>PDXS_MYCLE (O07145) Pyridoxal biosynthesis lyase pdxS (EC 4.-.-.-)| Length = 307 Score = 30.8 bits (68), Expect = 3.1 Identities = 20/77 (25%), Positives = 37/77 (48%), Gaps = 3/77 (3%) Frame = +2 Query: 194 SSPPRNIMSFKIGSDGNLQGVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEIN 373 ++P M ++G++G G GIF + DPA ++ + D L +++ Sbjct: 229 ATPADAAMMMQLGAEGIFVGSGIFKSSDPAQRAAAIVKA-------TTFYDDPDVLAKVS 281 Query: 374 ---GNSVLGLDVEAVAQ 415 G ++ G+DVE +AQ Sbjct: 282 RGLGEAMAGIDVEQIAQ 298
>GOPC_HUMAN (Q9HD26) Golgi-associated PDZ and coiled-coil motif-containing| protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma) Length = 462 Score = 30.8 bits (68), Expect = 3.1 Identities = 22/66 (33%), Positives = 33/66 (50%), Gaps = 2/66 (3%) Frame = +2 Query: 185 SQRSSPPRNIMSFKIGSDGNLQGVGIFINRDPATG-RLLVMNCIDGGPADRAG-IHEGDE 358 SQ P R ++ K + +G+GI I G +L+ G PADR G +H GD Sbjct: 280 SQGVGPIRKVLLLK----EDHEGLGISITGGKEHGVPILISEIHPGQPADRCGGLHVGDA 335 Query: 359 LVEING 376 ++ +NG Sbjct: 336 ILAVNG 341
>Y161_RICPR (Q9ZE02) Hypothetical zinc metalloprotease RP161 (EC 3.4.24.-)| Length = 359 Score = 30.8 bits (68), Expect = 3.1 Identities = 11/30 (36%), Positives = 21/30 (70%) Frame = +2 Query: 296 LVMNCIDGGPADRAGIHEGDELVEINGNSV 385 ++ + + PA+RAG+ EGD++V++N V Sbjct: 132 IIGDVVAASPAERAGLKEGDKIVKVNNKYV 161
>WSP1_SCHPO (O36027) Wiskott-Aldrich syndrome homolog protein 1| Length = 574 Score = 30.8 bits (68), Expect = 3.1 Identities = 23/82 (28%), Positives = 30/82 (36%), Gaps = 4/82 (4%) Frame = -2 Query: 471 PVPSNSFTSTVVPARP----LSL*ATASTSNPKTLFPLISTSSSPSCMPALSAGPPSMQF 304 P P + PA P S +T P +L P S PS P+L G P+ Sbjct: 389 PAPPPAIPGRSAPALPPLGNASRTSTPPVPTPPSLPPSAPPSLPPSAPPSLPMGAPAAPP 448 Query: 303 ITSKRPVAGSLFMNMPTPCKFP 238 + P+A L MP P Sbjct: 449 LPPSAPIAPPLPAGMPAAPPLP 470
>SHAN2_RAT (Q9QX74) SH3 and multiple ankyrin repeat domains protein 2 (Shank2)| (Proline-rich synapse-associated protein 1) (ProSAP1) (Cortactin-binding protein 1) (CortBP1) (GKAP/SAPAP-interacting protein) (SPANK-3) Length = 1474 Score = 30.8 bits (68), Expect = 3.1 Identities = 20/65 (30%), Positives = 35/65 (53%), Gaps = 1/65 (1%) Frame = +2 Query: 278 PATGRLLVMNCID-GGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVK 454 PA L + +D GG A +AG+ GD L+E+N +V+ + V +R + G + +K Sbjct: 279 PAFPALQYLESVDEGGVAWQAGLRTGDFLIEVNNENVVKVGHRQVVNMIR-QGGNHLVLK 337 Query: 455 LLDGT 469 ++ T Sbjct: 338 VVTVT 342
>SHAN2_HUMAN (Q9UPX8) SH3 and multiple ankyrin repeat domains protein 2 (Shank2)| Length = 1253 Score = 30.8 bits (68), Expect = 3.1 Identities = 20/65 (30%), Positives = 35/65 (53%), Gaps = 1/65 (1%) Frame = +2 Query: 278 PATGRLLVMNCID-GGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVK 454 PA L + +D GG A +AG+ GD L+E+N +V+ + V +R + G + +K Sbjct: 68 PAFPALQYLESVDEGGVAWQAGLRTGDFLIEVNNENVVKVGHRQVVNMIR-QGGNHLVLK 126 Query: 455 LLDGT 469 ++ T Sbjct: 127 VVTVT 131
>GOPC_MOUSE (Q8BH60) Golgi-associated PDZ and coiled-coil motif-containing| protein (PDZ protein interacting specifically with TC10) (PIST) Length = 463 Score = 30.8 bits (68), Expect = 3.1 Identities = 22/66 (33%), Positives = 33/66 (50%), Gaps = 2/66 (3%) Frame = +2 Query: 185 SQRSSPPRNIMSFKIGSDGNLQGVGIFINRDPATG-RLLVMNCIDGGPADRAG-IHEGDE 358 SQ P R ++ K + +G+GI I G +L+ G PADR G +H GD Sbjct: 281 SQGVGPIRKVLLLK----EDHEGLGISITGGKEHGVPILISEIHPGQPADRCGGLHVGDA 336 Query: 359 LVEING 376 ++ +NG Sbjct: 337 ILAVNG 342
>CUT20_SCHPO (O42839) 20S cyclosome/APC complex protein cut20 (Cell untimely| torn protein 20) Length = 719 Score = 30.4 bits (67), Expect = 4.0 Identities = 19/81 (23%), Positives = 39/81 (48%) Frame = +2 Query: 260 IFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGT 439 +F +D L++ ++ +G H G + E+ G+S+L + T Sbjct: 570 LFFRKDTPNIFLIISQLMENTMLPVSGCHFGLDYAELLGSSLLDF-----------QPAT 618 Query: 440 TVEVKLLDGTGIERSGRIKQK 502 +++KLL+G+ I G++K+K Sbjct: 619 VLDMKLLNGSSILILGKLKEK 639
>RET_MOUSE (P35546) Proto-oncogene tyrosine-protein kinase receptor ret| precursor (EC 2.7.10.1) (C-ret) Length = 1115 Score = 30.4 bits (67), Expect = 4.0 Identities = 21/52 (40%), Positives = 27/52 (51%), Gaps = 1/52 (1%) Frame = +2 Query: 374 GNSVLGLDVEAVAQRLRGRAG-TTVEVKLLDGTGIERSGRIKQKEVQLSREV 526 G G V+A A RL+GRAG TTV VK+L + R E L ++V Sbjct: 732 GEGEFGKVVKATAFRLKGRAGYTTVAVKMLKENASQSELRDLLSEFNLLKQV 783
>Y1355_LISIN (Q92C36) Hypothetical zinc metalloprotease Lin1355 (EC 3.4.24.-)| Length = 420 Score = 30.4 bits (67), Expect = 4.0 Identities = 19/69 (27%), Positives = 34/69 (49%) Frame = +2 Query: 305 NCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLLDGTGIERS 484 N + G A +AG+ +GDE++ ING + Q + G T++ K I+R Sbjct: 207 NIMPDGAAAQAGLEKGDEVLSINGKETKSW--TDIVQSVSENPGKTLDFK------IDRD 258 Query: 485 GRIKQKEVQ 511 G+ + +V+ Sbjct: 259 GKTQDIDVK 267
>PPDK_FLATR (P22221) Pyruvate, phosphate dikinase, chloroplast precursor (EC| 2.7.9.1) (Pyruvate, orthophosphate dikinase) Length = 953 Score = 30.4 bits (67), Expect = 4.0 Identities = 12/27 (44%), Positives = 16/27 (59%) Frame = +2 Query: 209 NIMSFKIGSDGNLQGVGIFINRDPATG 289 NI S G+ GN G G+ R+P+TG Sbjct: 318 NIQSMVFGNMGNTSGTGVLFTRNPSTG 344
>PPDK_FLABI (Q39735) Pyruvate, phosphate dikinase, chloroplast precursor (EC| 2.7.9.1) (Pyruvate, orthophosphate dikinase) (Cold-sensitive pyruvate, orthophosphate dikinase) Length = 953 Score = 30.4 bits (67), Expect = 4.0 Identities = 12/27 (44%), Positives = 16/27 (59%) Frame = +2 Query: 209 NIMSFKIGSDGNLQGVGIFINRDPATG 289 NI S G+ GN G G+ R+P+TG Sbjct: 318 NIQSMVFGNMGNTSGTGVLFTRNPSTG 344
>Y203_RICCN (Q92J66) Hypothetical zinc metalloprotease RC0203 (EC 3.4.24.-)| Length = 358 Score = 30.0 bits (66), Expect = 5.2 Identities = 11/30 (36%), Positives = 20/30 (66%) Frame = +2 Query: 296 LVMNCIDGGPADRAGIHEGDELVEINGNSV 385 ++ N + PA+RA + GD++V++N SV Sbjct: 130 IIGNVVASSPAERADLRAGDKIVKVNDKSV 159
>MPP6_HUMAN (Q9NZW5) MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1)| (VAM-1) Length = 540 Score = 30.0 bits (66), Expect = 5.2 Identities = 19/57 (33%), Positives = 35/57 (61%), Gaps = 1/57 (1%) Frame = +2 Query: 293 LLVMNCIDGGPADRAGI-HEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLL 460 L++ + GG DR G+ H GD + E+NG+ V G + + + + L+ +G +V +K+L Sbjct: 152 LVIARILHGGMIDRQGLLHVGDIIKEVNGHEV-GNNPKELQELLKNISG-SVTLKIL 206
>LIN7A_MOUSE (Q8JZS0) LIN-7 homolog A (LIN-7A) (mLin-7) (Mammalian LIN-seven| protein 1) (MALS-1) (Vertebrate LIN 7 homolog 1) (Veli-1 protein) Length = 233 Score = 30.0 bits (66), Expect = 5.2 Identities = 16/45 (35%), Positives = 25/45 (55%), Gaps = 1/45 (2%) Frame = +2 Query: 293 LLVMNCIDGGPADR-AGIHEGDELVEINGNSVLGLDVEAVAQRLR 424 + + I GG A+R G+ GD+L+ +NG SV G E + L+ Sbjct: 132 IYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLK 176
>LIN7A_HUMAN (O14910) LIN-7 homolog A (LIN-7A) (hLin-7) (Mammalian LIN-seven| protein 1) (MALS-1) (Vertebrate LIN 7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33) Length = 233 Score = 30.0 bits (66), Expect = 5.2 Identities = 16/45 (35%), Positives = 25/45 (55%), Gaps = 1/45 (2%) Frame = +2 Query: 293 LLVMNCIDGGPADR-AGIHEGDELVEINGNSVLGLDVEAVAQRLR 424 + + I GG A+R G+ GD+L+ +NG SV G E + L+ Sbjct: 132 IYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLK 176
>ODPX_HUMAN (O00330) Pyruvate dehydrogenase protein X component, mitochondrial| precursor (Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex) (Lipoyl-containing pyruvate dehydrogenase complex component X) (E3-binding protein) Length = 501 Score = 30.0 bits (66), Expect = 5.2 Identities = 15/44 (34%), Positives = 21/44 (47%) Frame = -2 Query: 444 TVVPARPLSL*ATASTSNPKTLFPLISTSSSPSCMPALSAGPPS 313 T P P L ATA S P+ + P +ST P+ + + P S Sbjct: 238 TATPTAPSPLQATAGPSYPRPVIPPVSTPGQPNAVGTFTEIPAS 281
>MPP6_MOUSE (Q9JLB0) MAGUK p55 subfamily member 6 (Protein associated with| Lin-7 2) (Dlgh4 protein) (P55T protein) Length = 553 Score = 30.0 bits (66), Expect = 5.2 Identities = 19/57 (33%), Positives = 35/57 (61%), Gaps = 1/57 (1%) Frame = +2 Query: 293 LLVMNCIDGGPADRAGI-HEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLL 460 L++ + GG DR G+ H GD + E+NG+ V G + + + + L+ +G +V +K+L Sbjct: 151 LVIARILHGGMIDRQGLLHVGDIIKEVNGHEV-GNNPKELQELLKNISG-SVTLKIL 205
>TFR1_CRIGR (Q07891) Transferrin receptor protein 1 (TfR1) (TR) (TfR) (Trfr)| Length = 757 Score = 30.0 bits (66), Expect = 5.2 Identities = 21/56 (37%), Positives = 27/56 (48%), Gaps = 1/56 (1%) Frame = -2 Query: 411 ATASTSNPKTL-FPLISTSSSPSCMPALSAGPPSMQFITSKRPVAGSLFMNMPTPC 247 A T +P T FP + + P P+ S+G PS+ T R A LF NM T C Sbjct: 298 AHLGTGDPYTPGFPSFNHTQFP---PSQSSGLPSIPVQTISRKAAEKLFQNMETNC 350
>SYNP2_MOUSE (Q91YE8) Synaptopodin-2 (Myopodin)| Length = 1087 Score = 30.0 bits (66), Expect = 5.2 Identities = 14/34 (41%), Positives = 19/34 (55%) Frame = +2 Query: 326 ADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRG 427 A +G+ EGDE+V INGN L V + + G Sbjct: 42 ASGSGLREGDEVVSINGNPCADLTYPEVIKLMEG 75
>MUC15_BOVIN (Q8MI01) Mucin-15 precursor (PASIII) (PAS3) (Glycoprotein C)| (Glycoprotein 4) (Component II) Length = 330 Score = 30.0 bits (66), Expect = 5.2 Identities = 17/43 (39%), Positives = 20/43 (46%) Frame = -2 Query: 366 STSSSPSCMPALSAGPPSMQFITSKRPVAGSLFMNMPTPCKFP 238 ++S SPS MP LS PS SK P S+ N P P Sbjct: 94 NSSRSPSLMPTLSPRSPSTHSFVSKLPWNSSIADNSLLPASAP 136
>TEGU_EBV (P03186) Large tegument protein| Length = 3149 Score = 30.0 bits (66), Expect = 5.2 Identities = 22/60 (36%), Positives = 29/60 (48%) Frame = -2 Query: 492 ILPLLSIPVPSNSFTSTVVPARPLSL*ATASTSNPKTLFPLISTSSSPSCMPALSAGPPS 313 I+P P+PS SFTS PA S A T++P P S++P+ SA P S Sbjct: 300 IIPYNLRPLPSRSFTSDSFPAARYS---PAKTNSP----PSSPASAAPASAAPASAAPAS 352
>RHPN1_HUMAN (Q8TCX5) Rhophilin-1 (GTP-Rho-binding protein 1)| Length = 695 Score = 30.0 bits (66), Expect = 5.2 Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 2/69 (2%) Frame = +2 Query: 251 GVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLR-- 424 G G+ + D +L+ I G A AG+ EGD +V +NG V L+ Sbjct: 547 GFGLTLRGDSP---VLIAAVIPGSQAAAAGLKEGDYIVSVNGQPCRWWRHAEVVTELKAA 603 Query: 425 GRAGTTVEV 451 G AG +++V Sbjct: 604 GEAGASLQV 612
>LIN7A_RAT (Q9Z250) LIN-7 homolog A (LIN-7A) (Mammalian LIN-seven protein 1)| (MALS-1) (Vertebrate LIN 7 homolog 1) (Veli-1 protein) Length = 232 Score = 30.0 bits (66), Expect = 5.2 Identities = 16/45 (35%), Positives = 25/45 (55%), Gaps = 1/45 (2%) Frame = +2 Query: 293 LLVMNCIDGGPADR-AGIHEGDELVEINGNSVLGLDVEAVAQRLR 424 + + I GG A+R G+ GD+L+ +NG SV G E + L+ Sbjct: 132 IYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLK 176
>HTRA1_HUMAN (Q92743) Serine protease HTRA1 precursor (EC 3.4.21.-) (L56)| Length = 480 Score = 29.6 bits (65), Expect = 6.8 Identities = 15/41 (36%), Positives = 23/41 (56%), Gaps = 1/41 (2%) Frame = +2 Query: 299 VMNCIDGGPADRAGIHEGDELVEINGNSVLGL-DVEAVAQR 418 ++ I PA+ G+ E D ++ ING SV+ DV V +R Sbjct: 414 IIEVIPDTPAEAGGLKENDVIISINGQSVVSANDVSDVIKR 454
>DEGP_BRUSU (P0A3Z5) Probable serine protease do-like precursor (EC 3.4.21.-)| Length = 513 Score = 29.6 bits (65), Expect = 6.8 Identities = 12/24 (50%), Positives = 16/24 (66%) Frame = +2 Query: 314 DGGPADRAGIHEGDELVEINGNSV 385 D GPA +AGI GD + +NG +V Sbjct: 342 DDGPAAKAGIKAGDVITAVNGETV 365
>DEGP_BRUME (Q8YG32) Probable serine protease do-like precursor (EC 3.4.21.-)| Length = 513 Score = 29.6 bits (65), Expect = 6.8 Identities = 12/24 (50%), Positives = 16/24 (66%) Frame = +2 Query: 314 DGGPADRAGIHEGDELVEINGNSV 385 D GPA +AGI GD + +NG +V Sbjct: 342 DDGPAAKAGIKAGDVITAVNGETV 365
>DEGP_BRUAB (P0C114) Probable serine protease do-like precursor (EC 3.4.21.-)| Length = 513 Score = 29.6 bits (65), Expect = 6.8 Identities = 12/24 (50%), Positives = 16/24 (66%) Frame = +2 Query: 314 DGGPADRAGIHEGDELVEINGNSV 385 D GPA +AGI GD + +NG +V Sbjct: 342 DDGPAAKAGIKAGDVITAVNGETV 365
>DEGP_BRUA2 (Q2YMX6) Probable serine protease do-like precursor (EC 3.4.21.-)| Length = 513 Score = 29.6 bits (65), Expect = 6.8 Identities = 12/24 (50%), Positives = 16/24 (66%) Frame = +2 Query: 314 DGGPADRAGIHEGDELVEINGNSV 385 D GPA +AGI GD + +NG +V Sbjct: 342 DDGPAAKAGIKAGDVITAVNGETV 365
>K1849_HUMAN (Q96JH8) Protein KIAA1849| Length = 1073 Score = 29.6 bits (65), Expect = 6.8 Identities = 14/35 (40%), Positives = 22/35 (62%), Gaps = 1/35 (2%) Frame = +2 Query: 293 LLVMNCIDGGPADRAG-IHEGDELVEINGNSVLGL 394 L + + G PA G + GD ++E+NG+S+LGL Sbjct: 1001 LYIQTLLPGSPAAADGRLSLGDRILEVNGSSLLGL 1035
>SOP2_CAEEL (Q965H3) Polycomb protein sop-2 (Suppressor of pal-1 protein 2)| Length = 735 Score = 29.6 bits (65), Expect = 6.8 Identities = 22/73 (30%), Positives = 33/73 (45%) Frame = -2 Query: 438 VPARPLSL*ATASTSNPKTLFPLISTSSSPSCMPALSAGPPSMQFITSKRPVAGSLFMNM 259 +P R + +T+ K P STSSSP PA A P S S R + +F Sbjct: 464 IPKRSEAAPEVPATATTKEAPP--STSSSPPDAPATPATPASSDSRDSPRKIRAMIFSLT 521 Query: 258 PTPCKFPSLPILK 220 +P + + P+L+ Sbjct: 522 GSPPESETPPVLQ 534
>SN1L2_HUMAN (Q9H0K1) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Qin-induced kinase) Length = 926 Score = 29.6 bits (65), Expect = 6.8 Identities = 24/101 (23%), Positives = 39/101 (38%), Gaps = 13/101 (12%) Frame = -2 Query: 501 FCFILPLLSIPVPSNS---FTSTVVPARPLSL*ATASTSNPKTLFPLISTSSS------- 352 F PL + PS+ ++ + + + L STS P+ PL + Sbjct: 768 FSLTQPLSPVLEPSSEQMQYSPFLSQYQEMQLQPLPSTSGPRAAPPLPTQLQQQQPPPPP 827 Query: 351 ---PSCMPALSAGPPSMQFITSKRPVAGSLFMNMPTPCKFP 238 P P + P + T + P A S + PTPC++P Sbjct: 828 PPPPPRQPGAAPAPLQFSYQTCELPSAASPAPDYPTPCQYP 868
>ENH2_HUMAN (Q9N2J9) HERV-H_3q26 provirus ancestral Env polyprotein precursor| (Envelope polyprotein) (Env protein HERV-H/p60) (HERV-H/env60) [Contains: Surface protein (SU); Transmembrane protein (TM)] Length = 563 Score = 29.6 bits (65), Expect = 6.8 Identities = 19/58 (32%), Positives = 30/58 (51%), Gaps = 5/58 (8%) Frame = -2 Query: 360 SSSPSCMPALSAGPPSMQFITSKRPVAGSLFMNMPTPCKFPS-----LPILKLMIFLG 202 SS+ C+PA G ++ F+TSK A +P P P+ +P++ LM+ LG Sbjct: 343 SSTYMCLPANWTGTCTLVFLTSKIQFANGT-EELPVPLMTPTRQKRVIPLIPLMVGLG 399
>YVTA_BACSU (Q9R9I1) Probable serine protease yvtA (EC 3.4.21.-)| Length = 458 Score = 29.6 bits (65), Expect = 6.8 Identities = 29/112 (25%), Positives = 48/112 (42%), Gaps = 2/112 (1%) Frame = +2 Query: 194 SSPPRNIMSFKIGSDGNLQGVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEIN 373 S P +G G+ G G+++ A PA++AGI D +V++N Sbjct: 360 SQVPETYQENTLGLFGDQLGKGVYVKEVQANS-----------PAEKAGIKSEDVIVKLN 408 Query: 374 GNSVLGLDVEAVAQRLRGRAGTTVEVKLLDGTGIE--RSGRIKQKEVQLSRE 523 G DVE+ A R ++K+ D T I+ R G+ K L+++ Sbjct: 409 GK-----DVESSADI---RQILYKDLKVGDKTTIQVLRKGKTKTLNATLTKQ 452
>NU153_HUMAN (P49790) Nuclear pore complex protein Nup153 (Nucleoporin Nup153)| (153 kDa nucleoporin) Length = 1475 Score = 29.6 bits (65), Expect = 6.8 Identities = 22/63 (34%), Positives = 27/63 (42%), Gaps = 14/63 (22%) Frame = -2 Query: 408 TASTSNPKTLFPLISTSSSPSCMPALSAG------------PPSMQFI--TSKRPVAGSL 271 TA K +F ++ SSS S PA SAG PP F+ S PV+ S Sbjct: 1180 TADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSA 1239 Query: 270 FMN 262 F N Sbjct: 1240 FGN 1242
>CRCB1_SYMTH (Q67S17) Protein crcB homolog 1| Length = 124 Score = 29.6 bits (65), Expect = 6.8 Identities = 26/64 (40%), Positives = 30/64 (46%) Frame = +2 Query: 281 ATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVKLL 460 A RLLV IDG P RA G V I G+ +LGL V GR EVK++ Sbjct: 14 AVARLLVGAWIDGRPGGRA-FPWGTFAVNIAGSLLLGLLTGLVV----GRGWLAPEVKVV 68 Query: 461 DGTG 472 G G Sbjct: 69 LGAG 72
>TLE4_RAT (Q07141) Transducin-like enhancer protein 4 (ESP2 protein)| Length = 741 Score = 29.3 bits (64), Expect = 8.9 Identities = 17/57 (29%), Positives = 28/57 (49%) Frame = -2 Query: 405 ASTSNPKTLFPLISTSSSPSCMPALSAGPPSMQFITSKRPVAGSLFMNMPTPCKFPS 235 ++T P+T P ++S+P P + PP + P+A SL M PC +P+ Sbjct: 291 SNTPTPRTDAPTPGSNSTPGLRP-VPGKPPGVD------PLASSLRTPMAVPCPYPT 340
>ARHGC_HUMAN (Q9NZN5) Rho guanine nucleotide exchange factor 12| (Leukemia-associated RhoGEF) Length = 1544 Score = 29.3 bits (64), Expect = 8.9 Identities = 14/45 (31%), Positives = 25/45 (55%) Frame = +2 Query: 251 GVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSV 385 G G+ ++ D + V + + G A RAG+ GD ++++NG V Sbjct: 81 GFGLTVSGD---NPVFVQSVKEDGAAMRAGVQTGDRIIKVNGTLV 122
>ZDH24_HUMAN (Q6UX98) Probable palmitoyltransferase ZDHHC24 (EC 2.3.1.-) (Zinc| finger DHHC domain-containing protein 24) (DHHC-24) Length = 284 Score = 29.3 bits (64), Expect = 8.9 Identities = 11/20 (55%), Positives = 13/20 (65%) Frame = +1 Query: 238 WEFARGWHIHK*GPCHRTLA 297 WE+ARG H + GPCH A Sbjct: 228 WEWARGQHSYDLGPCHNLQA 247
>YCX9_CHLVU (O20173) Hypothetical 27.9 kDa protein in trnR-minE intergenic| region (ORF249) Length = 249 Score = 29.3 bits (64), Expect = 8.9 Identities = 31/102 (30%), Positives = 45/102 (44%), Gaps = 7/102 (6%) Frame = -2 Query: 501 FCFILPLLSIPVPS--NSFTSTVVPARPLS-----L*ATASTSNPKTLFPLISTSSSPSC 343 F ++P S+P S + +ST+ P R L A+ S S KT ST SS Sbjct: 55 FLLMVPSTSVPNASLESGQSSTISPRRQKESSIPVLQASGSVSANKTFQ---STESSALH 111 Query: 342 MPALSAGPPSMQFITSKRPVAGSLFMNMPTPCKFPSLPILKL 217 P S+ + + IT +RP +G + P+L LKL Sbjct: 112 QPKSSSSERTGKIITRQRPHSGPTSPRVTPGELLPTLEALKL 153
>SHAN3_RAT (Q9JLU4) SH3 and multiple ankyrin repeat domains 3 (Shank3)| (Proline-rich synapse associated protein 2) (ProSAP2) (SPANK-2) Length = 1815 Score = 29.3 bits (64), Expect = 8.9 Identities = 20/65 (30%), Positives = 36/65 (55%), Gaps = 1/65 (1%) Frame = +2 Query: 278 PATGRLLVMNCID-GGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGTTVEVK 454 PA L + +D G A +AG+ GD L+E+NG +V+ + + V +R + G + +K Sbjct: 676 PAFPALQYLESVDVEGVAWKAGLRTGDFLIEVNGVNVVKVGHKQVVGLIR-QGGNRLVMK 734 Query: 455 LLDGT 469 ++ T Sbjct: 735 VVSVT 739
>LIMK2_CHICK (P53666) LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2)| Length = 642 Score = 29.3 bits (64), Expect = 8.9 Identities = 19/54 (35%), Positives = 28/54 (51%), Gaps = 1/54 (1%) Frame = +2 Query: 281 ATG-RLLVMNCIDGGPADRAGIHEGDELVEINGNSVLGLDVEAVAQRLRGRAGT 439 ATG ++ +N + P R IH D ++EING + L VE V +R + T Sbjct: 177 ATGVQVKEVNRMHISPDVRNAIHPADRILEINGAPIRTLQVEEVEDLIRKTSQT 230
>TLE4_MOUSE (Q62441) Transducin-like enhancer protein 4 (Groucho-related| protein 4) (Grg-4) Length = 766 Score = 29.3 bits (64), Expect = 8.9 Identities = 17/57 (29%), Positives = 28/57 (49%) Frame = -2 Query: 405 ASTSNPKTLFPLISTSSSPSCMPALSAGPPSMQFITSKRPVAGSLFMNMPTPCKFPS 235 ++T P+T P ++S+P P + PP + P+A SL M PC +P+ Sbjct: 316 SNTPTPRTDAPTPGSNSTPGLRP-VPGKPPGVD------PLASSLRTPMAVPCPYPT 365
>TLE4_HUMAN (Q04727) Transducin-like enhancer protein 4| Length = 766 Score = 29.3 bits (64), Expect = 8.9 Identities = 17/57 (29%), Positives = 28/57 (49%) Frame = -2 Query: 405 ASTSNPKTLFPLISTSSSPSCMPALSAGPPSMQFITSKRPVAGSLFMNMPTPCKFPS 235 ++T P+T P ++S+P P + PP + P+A SL M PC +P+ Sbjct: 316 SNTPTPRTDAPTPGSNSTPGLRP-VPGKPPGVD------PLASSLRTPMAVPCPYPT 365
>PDXS_MYCPA (Q73WF0) Pyridoxal biosynthesis lyase pdxS (EC 4.-.-.-)| Length = 303 Score = 29.3 bits (64), Expect = 8.9 Identities = 19/77 (24%), Positives = 38/77 (49%), Gaps = 3/77 (3%) Frame = +2 Query: 194 SSPPRNIMSFKIGSDGNLQGVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEIN 373 ++P M ++G++G G GIF + DPA ++ + D L +++ Sbjct: 225 ATPADAAMMMQLGAEGVFVGSGIFKSGDPAQRAAAIVKA-------TTFYDDPDVLAKVS 277 Query: 374 ---GNSVLGLDVEAVAQ 415 G +++G++VE +AQ Sbjct: 278 RGLGEAMVGINVEQIAQ 294
>PAR6A_RAT (Q6B4M5) Partitioning defective 6 homolog alpha (PAR-6 alpha)| (PAR-6A) (PAR-6) Length = 346 Score = 29.3 bits (64), Expect = 8.9 Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 1/73 (1%) Frame = +2 Query: 206 RNIMSFKIGSDGNLQGVGIFINRDPATGRLLVMNCIDGGPADRAGIHE-GDELVEINGNS 382 R+ MS ++ G + GIFI+R + GG A+ G+ DE++E+NG Sbjct: 174 RDGMSVRVAPQGLERVPGIFISR-----------LVRGGLAESTGLLAVSDEILEVNGIE 222 Query: 383 VLGLDVEAVAQRL 421 V G ++ V + Sbjct: 223 VAGKTLDQVTDMM 235
>PAR6A_MOUSE (Q9Z101) Partitioning defective 6 homolog alpha (PAR-6 alpha)| (PAR-6A) (PAR-6) Length = 346 Score = 29.3 bits (64), Expect = 8.9 Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 1/73 (1%) Frame = +2 Query: 206 RNIMSFKIGSDGNLQGVGIFINRDPATGRLLVMNCIDGGPADRAGIHE-GDELVEINGNS 382 R+ MS ++ G + GIFI+R + GG A+ G+ DE++E+NG Sbjct: 174 RDGMSVRVAPQGLERVPGIFISR-----------LVRGGLAESTGLLAVSDEILEVNGIE 222 Query: 383 VLGLDVEAVAQRL 421 V G ++ V + Sbjct: 223 VAGKTLDQVTDMM 235
>PAR6A_HUMAN (Q9NPB6) Partitioning defective 6 homolog alpha (PAR-6 alpha)| (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40) Length = 346 Score = 29.3 bits (64), Expect = 8.9 Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 1/73 (1%) Frame = +2 Query: 206 RNIMSFKIGSDGNLQGVGIFINRDPATGRLLVMNCIDGGPADRAGIHE-GDELVEINGNS 382 R+ MS ++ G + GIFI+R + GG A+ G+ DE++E+NG Sbjct: 174 RDGMSVRVAPQGLERVPGIFISR-----------LVRGGLAESTGLLAVSDEILEVNGIE 222 Query: 383 VLGLDVEAVAQRL 421 V G ++ V + Sbjct: 223 VAGKTLDQVTDMM 235
>ARHGC_MOUSE (Q8R4H2) Rho guanine nucleotide exchange factor 12| (Leukemia-associated RhoGEF) Length = 1543 Score = 29.3 bits (64), Expect = 8.9 Identities = 14/45 (31%), Positives = 25/45 (55%) Frame = +2 Query: 251 GVGIFINRDPATGRLLVMNCIDGGPADRAGIHEGDELVEINGNSV 385 G G+ ++ D + V + + G A RAG+ GD ++++NG V Sbjct: 81 GFGLTVSGD---NPVFVQSVKEDGAAMRAGVQTGDRIIKVNGTLV 122 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 84,427,116 Number of Sequences: 219361 Number of extensions: 1754310 Number of successful extensions: 5628 Number of sequences better than 10.0: 209 Number of HSP's better than 10.0 without gapping: 5280 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5609 length of database: 80,573,946 effective HSP length: 106 effective length of database: 57,321,680 effective search space used: 5158951200 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
