ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | baal33p20 |
|---|---|
| Clone Library Name | barley_pub |
>LCFA_SALTY (P63521) Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase) Length = 561 Score = 96.3 bits (238), Expect = 7e-20 Identities = 59/162 (36%), Positives = 83/162 (51%), Gaps = 2/162 (1%) Frame = +1 Query: 145 TVFTGVPTVYTRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCHR 324 T TGV T++ LL + D S L L G + + + +RW ++T Sbjct: 301 TAMTGVNTLFNALLNNKEFQQLDFSS--------LHLSAGGGMPVQNVVAERWVKLTGQY 352 Query: 325 LLERYGMTEFVMALS-NPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDG-VGELCIKSP 498 LLE YG+TE +S NP G++G P+P EAK++ DD E G GELC+K P Sbjct: 353 LLEGYGLTECAPLVSVNPHDIDYHSGSIGLPVPSTEAKLVDDDDNEVAPGEAGELCVKGP 412 Query: 499 SLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 + YW+RP+ T E I G+ TGD +DEDG+ I+ R Sbjct: 413 QVMLGYWQRPDATDE-IIKDGWLHTGDIAVMDEDGFLRIVDR 453
>LCFA_SALTI (P63522) Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase) Length = 561 Score = 96.3 bits (238), Expect = 7e-20 Identities = 59/162 (36%), Positives = 83/162 (51%), Gaps = 2/162 (1%) Frame = +1 Query: 145 TVFTGVPTVYTRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCHR 324 T TGV T++ LL + D S L L G + + + +RW ++T Sbjct: 301 TAMTGVNTLFNALLNNKEFQQLDFSS--------LHLSAGGGMPVQNVVAERWVKLTGQY 352 Query: 325 LLERYGMTEFVMALS-NPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDG-VGELCIKSP 498 LLE YG+TE +S NP G++G P+P EAK++ DD E G GELC+K P Sbjct: 353 LLEGYGLTECAPLVSVNPHDIDYHSGSIGLPVPSTEAKLVDDDDNEVAPGEAGELCVKGP 412 Query: 499 SLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 + YW+RP+ T E I G+ TGD +DEDG+ I+ R Sbjct: 413 QVMLGYWQRPDATDE-IIKDGWLHTGDIAVMDEDGFLRIVDR 453
>LCFA_ECOLI (P69451) Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase) (Acyl-CoA synthetase) Length = 561 Score = 94.7 bits (234), Expect = 2e-19 Identities = 58/162 (35%), Positives = 82/162 (50%), Gaps = 2/162 (1%) Frame = +1 Query: 145 TVFTGVPTVYTRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCHR 324 T TGV T++ LL + D S L L G + + +RW ++T Sbjct: 301 TAITGVNTLFNALLNNKEFQQLDFSS--------LHLSAGGGMPVQQVVAERWVKLTGQY 352 Query: 325 LLERYGMTEFVMALS-NPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSP 498 LLE YG+TE +S NP G++G P+P EAK++ DD E G GELC+K P Sbjct: 353 LLEGYGLTECAPLVSVNPYDIDYHSGSIGLPVPSTEAKLVDDDDNEVPPGQPGELCVKGP 412 Query: 499 SLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 + YW+RP+ T E I G+ TGD +DE+G+ I+ R Sbjct: 413 QVMLGYWQRPDATDE-IIKNGWLHTGDIAVMDEEGFLRIVDR 453
>LCFA_ECOL6 (P69452) Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase) (Acyl-CoA synthetase) Length = 561 Score = 94.7 bits (234), Expect = 2e-19 Identities = 58/162 (35%), Positives = 82/162 (50%), Gaps = 2/162 (1%) Frame = +1 Query: 145 TVFTGVPTVYTRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCHR 324 T TGV T++ LL + D S L L G + + +RW ++T Sbjct: 301 TAITGVNTLFNALLNNKEFQQLDFSS--------LHLSAGGGMPVQQVVAERWVKLTGQY 352 Query: 325 LLERYGMTEFVMALS-NPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSP 498 LLE YG+TE +S NP G++G P+P EAK++ DD E G GELC+K P Sbjct: 353 LLEGYGLTECAPLVSVNPYDIDYHSGSIGLPVPSTEAKLVDDDDNEVPPGQPGELCVKGP 412 Query: 499 SLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 + YW+RP+ T E I G+ TGD +DE+G+ I+ R Sbjct: 413 QVMLGYWQRPDATDE-IIKNGWLHTGDIAVMDEEGFLRIVDR 453
>LCFA_ECO57 (Q8XDR6) Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase) (Acyl-CoA synthetase) Length = 561 Score = 94.0 bits (232), Expect = 3e-19 Identities = 57/162 (35%), Positives = 82/162 (50%), Gaps = 2/162 (1%) Frame = +1 Query: 145 TVFTGVPTVYTRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCHR 324 T TGV T++ LL + D S L L G + + +RW ++T Sbjct: 301 TAITGVNTLFNALLNNKEFQQLDFSS--------LHLSAGGGMPVQQVVAERWVKLTGQY 352 Query: 325 LLERYGMTEFVMALS-NPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSP 498 LLE YG+TE +S NP G++G P+P EAK++ DD E G GELC++ P Sbjct: 353 LLEGYGLTECAPLVSVNPYDIDYHSGSIGLPVPSTEAKLVDDDDNEVSPGQPGELCVRGP 412 Query: 499 SLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 + YW+RP+ T E I G+ TGD +DE+G+ I+ R Sbjct: 413 QVMLGYWQRPDATDE-IIKNGWLHTGDIAVMDEEGFLRIVDR 453
>LCFA_HAEIN (P46450) Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase) Length = 562 Score = 92.0 bits (227), Expect = 1e-18 Identities = 56/159 (35%), Positives = 85/159 (53%), Gaps = 2/159 (1%) Frame = +1 Query: 154 TGVPTVYTRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCHRLLE 333 TGV T++ LL + D + L+L + G A+ + RW E+T ++E Sbjct: 306 TGVNTLFNALLNNENFKEVDFSA--------LKLSVGGGMAIQQSVATRWHELTGCNIIE 357 Query: 334 RYGMTEFVMALSN-PLHGARKEGTVGKPLPRVEAKIIMDDGTETKDG-VGELCIKSPSLF 507 YGMTE ++ P++ + GT+G P+P + KII DDG++ K G GEL +K + Sbjct: 358 GYGMTECSPLIAACPINVVKHNGTIGVPVPNTDIKIIKDDGSDAKIGEAGELWVKGDQVM 417 Query: 508 KEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 + YW+RPE T+E D G+ TGD V +DE I+ R Sbjct: 418 RGYWQRPEATSEVLKD-GWMATGDIVIMDESYSLRIVDR 455
>LCFA_BACSU (P94547) Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase) Length = 560 Score = 90.9 bits (224), Expect = 3e-18 Identities = 57/163 (34%), Positives = 89/163 (54%), Gaps = 3/163 (1%) Frame = +1 Query: 145 TVFTGVPTVYTRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCHR 324 T+F G PT+Y LL +P+ Q Y ++ + GS+ALP + +++E+VT + Sbjct: 299 TLFPGAPTIYIGLLH-----HPELQH---YDLSSIKSCLSGSAALPVEVKQKFEKVTGGK 350 Query: 325 LLERYGMTEFV-MALSNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGV--GELCIKS 495 L+E YG++E + +N + G K G++G P P +A I ++ E GE+ +K Sbjct: 351 LVEGYGLSEASPVTHANFIWGKNKPGSIGCPWPSTDAAIYSEETGELAAPYEHGEIIVKG 410 Query: 496 PSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 P + K YW +PE TA DG F TGD +DE+G+F I R Sbjct: 411 PQVMKGYWNKPEETAAVLRDGWLF-TGDMGYMDEEGFFYIADR 452
>LCFA_YERPE (Q8ZES9) Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase) Length = 562 Score = 88.6 bits (218), Expect = 1e-17 Identities = 52/162 (32%), Positives = 84/162 (51%), Gaps = 2/162 (1%) Frame = +1 Query: 145 TVFTGVPTVYTRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCHR 324 T TGV T++ LL + + D + LRL + G + + ++WE +T Sbjct: 301 TAITGVNTLFNALLNNEEFTHLDFST--------LRLSVGGGMPVQKAVAEKWETLTGKH 352 Query: 325 LLERYGMTE-FVMALSNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDG-VGELCIKSP 498 LLE YG+TE + NP G++G P+P + ++ DDG + + G GEL ++ P Sbjct: 353 LLEGYGLTECSPLVTGNPYDLKHYSGSIGLPVPSTDVRLRDDDGNDVELGKPGELWVRGP 412 Query: 499 SLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 + YW+RP+ T + + G+ TGD T+DEDG+ I+ R Sbjct: 413 QVMLGYWQRPDAT-DDVLKDGWLATGDIATMDEDGFLRIVDR 453
>FAT2_SCHPO (O74976) Putative peroxisomal-coenzyme A synthetase (EC 6.-.-.-)| Length = 512 Score = 87.8 bits (216), Expect = 2e-17 Identities = 68/211 (32%), Positives = 96/211 (45%), Gaps = 3/211 (1%) Frame = +1 Query: 1 VHGLFNALFAPLYSGSVVEFMPKFSVRGVWQRWCESYPKGTSKNDEAITVFTGVPTVYTR 180 VHGL L + L SG PKFS W+ + + T +T VPT++ Sbjct: 214 VHGLLCGLLSTLASGGCAVVPPKFSAHSFWKEFIQY----------GATWYTAVPTIHQI 263 Query: 181 LLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEFVM 360 LL+ P + ++R + SS L P++ + E +LE Y MTE Sbjct: 264 LLR-----TPPPKPL-----PRIRFIRSCSSPLAPPVLSKLEATFRAPVLEAYAMTEASH 313 Query: 361 ALS-NPLHG-ARKEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPE 531 ++ NPL K +VGKP VE KI+ G E G GE+C++ ++ K Y P Sbjct: 314 QMTTNPLPPLVHKPHSVGKPFG-VELKILDQKGNEMPQGKEGEICVRGINVTKGYLNNPA 372 Query: 532 VTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 SF FF+TGD +D+DGY I GR Sbjct: 373 ANKSSFTKDRFFRTGDEGKLDKDGYVFITGR 403
>ACSA_BACSU (P39062) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) (Acetyl-CoA synthase) Length = 572 Score = 71.2 bits (173), Expect = 2e-12 Identities = 53/172 (30%), Positives = 82/172 (47%), Gaps = 5/172 (2%) Frame = +1 Query: 142 ITVFTGVPTVYTRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCH 321 + V+ PT + L+ D M A Y LR ++ L +++ +V Sbjct: 297 VNVWYSAPTAFRMLMGAGDEM------AAKYDLTSLRHVLSVGEPLNPEVIRWGHKVFNK 350 Query: 322 RLLERYGMTEFVMAL--SNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKD-GVGELCIK 492 R+ + + MTE L + P K G++GKP+P VEA I+ + G E +G L IK Sbjct: 351 RIHDTWWMTETGSQLICNYPCMDI-KPGSMGKPIPGVEAAIVDNQGNELPPYRMGNLAIK 409 Query: 493 S--PSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIM 642 PS+ W PE F+ GG++ +GD+ +DE+GYF GR + IM Sbjct: 410 KGWPSMMHTIWNNPEKYESYFMPGGWYVSGDSAYMDEEGYFWFQGRVDDVIM 461
>TYCB_BREPA (O30408) Tyrocidine synthetase 2 (Tyrocidine synthetase II)| [Includes: ATP-dependent proline adenylase (ProA) (Proline activase); ATP-dependent phenylalanine adenylase (PheA) (Phenylalanine activase); ATP-dependent D-phenylalanine adenylase (D Length = 3587 Score = 70.5 bits (171), Expect = 4e-12 Identities = 66/219 (30%), Positives = 100/219 (45%), Gaps = 13/219 (5%) Frame = +1 Query: 22 LFAPLYSGSVVEFMPKFSVRGVWQRWCESYPKGTSKNDEAITVFTGVPTVYTRLLQGYDS 201 +F PL SG+ + + + V +QR+ E D AIT T +P Y L+ Sbjct: 2743 MFGPLLSGATLYVLSR-DVINDFQRFAEYV------RDNAITFLT-LPPTYAIYLE---- 2790 Query: 202 MNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEFVMALSNPLH 381 P+Q LR ++ SA L+ +W+E + + YG TE + + L Sbjct: 2791 --PEQ-------VPSLRTLITAGSASSVALVDKWKEKVTY--VNGYGPTESTVCAT--LW 2837 Query: 382 GARKEG-----TVGKPLPRVEAKIIMDDGTETK--DGVGELCIKSPSLFKEYWKRPEVTA 540 A+ + T+GKP+ + I+ DD + K +GELCI SL + YW RPE+TA Sbjct: 2838 KAKPDEPVETITIGKPIQNTKLYIV-DDQLQLKAPGQMGELCISGLSLARGYWNRPELTA 2896 Query: 541 ESFIDGGF------FKTGDTVTVDEDGYFIILGRTNADI 639 E F+D F ++TGD DG LGR + + Sbjct: 2897 EKFVDNPFVPGTKMYRTGDLARWLPDGTIEYLGRIDHQV 2935 Score = 48.9 bits (115), Expect = 1e-05 Identities = 59/222 (26%), Positives = 91/222 (40%), Gaps = 17/222 (7%) Frame = +1 Query: 25 FAPLYSGSVVEFMPK------FSVRGVWQRWCESYPKGTSKNDEAITVFTGVPTVYTRLL 186 F + SGS V MP ++R + W SY VF VP+++ +L Sbjct: 1706 FTLIVSGSTVVLMPDHEAKDPIALRNLIAAWECSY-----------VVF--VPSMFQAIL 1752 Query: 187 QGYDSMNPDQQSACSYAA--KQLRLMMCGSSALPSPLMKRWEEVTCHR-LLERYGMTEF- 354 + CS A + ++ +M G L L++ + + ++ YG TE Sbjct: 1753 E------------CSTPADIRSIQAVMLGGEKLSPKLVQLCKAMHPQMSVMNAYGPTESS 1800 Query: 355 VMALSNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPE 531 VMA + T+G+P+ I+ GV GE+CI L + YWK+PE Sbjct: 1801 VMATYLRDTQPDQPITIGRPIANTAIYIVDQHHQLLPVGVVGEICIGGHGLARGYWKKPE 1860 Query: 532 VTAESFIDG------GFFKTGDTVTVDEDGYFIILGRTNADI 639 +TAE F+ +KTGD DG +GR + I Sbjct: 1861 LTAEKFVANPAVPGERMYKTGDLGRWLHDGTIDFIGRVDDQI 1902 Score = 43.1 bits (100), Expect = 7e-04 Identities = 28/87 (32%), Positives = 44/87 (50%), Gaps = 8/87 (9%) Frame = +1 Query: 403 VGKPLPRVEAKIIMDDGTETKDG--VGELCIKSPSLFKEYWKRPEVTAESFIDGGF---- 564 +GKP+ I+D+G + K VGEL I ++ + Y +PE+TAE F+D + Sbjct: 782 IGKPISNTGI-YILDEGLQLKPEGIVGELYISGANVGRGYLHQPELTAEKFLDNPYQPGE 840 Query: 565 --FKTGDTVTVDEDGYFIILGRTNADI 639 ++TGD DG LGR + + Sbjct: 841 RMYRTGDLALWLPDGQLEFLGRIDHQV 867
>MENE_LACLA (Q9CHK3) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 451 Score = 70.1 bits (170), Expect = 5e-12 Identities = 58/168 (34%), Positives = 85/168 (50%), Gaps = 3/168 (1%) Frame = +1 Query: 130 NDEAITVFTGVPTVYTRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEE 309 N I + + VPT+ TR+ S N LRL++ G +P PL+K+ +E Sbjct: 215 NSGKINMVSLVPTLLTRIADKLHSNN-------------LRLILLGGEFIPQPLIKKCQE 261 Query: 310 VTCHRLLERYGMTE-FVMALS-NPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGVGEL 483 + + + YGMTE F +++ N L K +VG+PLP VE +I D GVGE+ Sbjct: 262 LGL-PIYKTYGMTESFSQSVTFNILDFPDKTSSVGRPLPGVEIEIRQAD----LAGVGEI 316 Query: 484 CIKSPSLFKEY-WKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 +KSP L K Y ++P TA F+TGD +D DG+ +L R Sbjct: 317 WLKSPMLMKAYLGQKPYGTA--------FETGDIGYLDTDGFLYLLNR 356
>TYCC_BREPA (O30409) Tyrocidine synthetase 3 (Tyrocidine synthetase III)| [Includes: ATP-dependent asparagine adenylase (AsnA) (Asparagine activase); ATP-dependent glutamine adenylase (GlnA) (Glutamine activase); ATP-dependent tyrosine adenylase (TyrA) (Ty Length = 6486 Score = 68.9 bits (167), Expect = 1e-11 Identities = 54/179 (30%), Positives = 79/179 (44%), Gaps = 10/179 (5%) Frame = +1 Query: 133 DEAITVFTGVPTVYTRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEV 312 DE IT VP++ + M SAC+ L+ + CG AL L+ R+ E Sbjct: 1729 DEKITTLQMVPSLLDLV------MTDPGWSACT----SLQRVFCGGEALTPALVSRFYET 1778 Query: 313 TCHRLLERYGMTEFVMALSN---PLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGV-GE 480 +L+ YG TE + + P +GKP+ V ++ GV GE Sbjct: 1779 QQAQLINLYGPTETTIDATYWPCPRQQEYSAIPIGKPIDNVRLYVVNASNQLQPVGVAGE 1838 Query: 481 LCIKSPSLFKEYWKRPEVTAESFID------GGFFKTGDTVTVDEDGYFIILGRTNADI 639 LCI L + YW+R E+T SF+D G ++TGD V DG+ LGR + + Sbjct: 1839 LCIAGDGLARGYWQREELTKASFVDNPFEPGGTMYRTGDMVRYLPDGHIEYLGRIDHQV 1897 Score = 63.5 bits (153), Expect = 5e-10 Identities = 65/227 (28%), Positives = 98/227 (43%), Gaps = 16/227 (7%) Frame = +1 Query: 7 GLFNALFAPLYSGSVVEFMPKFSVRGVWQRWCESYPKGTSKNDEA--ITVFTGVPTVYTR 180 G +LFAPL G+ + + + P K A +T + GVP+++ Sbjct: 5854 GFVASLFAPLLGGATCVLPQEAAAKD---------PVALKKLMAATEVTHYYGVPSLFQA 5904 Query: 181 LLQGYDSMNPDQQSACSYAA--KQLRLMMCGSSALPSPLMKRWEEVTCHRLLE---RYGM 345 +L CS QLR + G LP L+++ +E H +E YG Sbjct: 5905 ILD------------CSTTTDFNQLRCVTLGGEKLPVQLVQKTKEK--HPAIEINNEYGP 5950 Query: 346 TE--FVMALSNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEY 516 TE V +S + A + T+G+PL V+ I+ + GV GELCI L + Y Sbjct: 5951 TENSVVTTISRSIE-AGQAITIGRPLANVQVYIVDEQHHLQPIGVVGELCIGGAGLARGY 6009 Query: 517 WKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNADI 639 +PE+TAE F+ F +KTGD V DG +GR + + Sbjct: 6010 LNKPELTAEKFVANPFRPGERMYKTGDLVKWRTDGTIEYIGRADEQV 6056 Score = 53.9 bits (128), Expect = 4e-07 Identities = 46/176 (26%), Positives = 79/176 (44%), Gaps = 11/176 (6%) Frame = +1 Query: 145 TVFTGVPTVYTRLLQGYDSMNPDQQSACSYAA--KQLRLMMCGSSALPSPLMKRWEEVTC 318 T+ TGVP+++ +L+ CS A + L+ + G + + L+++ +++ Sbjct: 2772 TLMTGVPSLFQAILE------------CSTPADIRPLQTVTLGGEKITAQLVEKCKQLNP 2819 Query: 319 HRLL-ERYGMTEF-VMALSNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCI 489 ++ YG TE V+A L G T+G+P+ I+ GV GE+CI Sbjct: 2820 DLVIVNEYGPTESSVVATWQRLAGPDAAITIGRPIANTSLYIVNQYHQLQPIGVVGEICI 2879 Query: 490 KSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNADI 639 L + YW +P +T E F+ F +KTGD DG +GR + + Sbjct: 2880 GGRGLARGYWNKPALTEEKFVSHPFAAGERMYKTGDLGKWLPDGTIEYIGRIDEQV 2935 Score = 52.0 bits (123), Expect = 2e-06 Identities = 50/182 (27%), Positives = 79/182 (43%), Gaps = 16/182 (8%) Frame = +1 Query: 142 ITVFTGVPTVYTRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSP----LMKRWEE 309 IT+F P + L+ D Q++L++ G+ + P+ L+ R+ + Sbjct: 4843 ITIFEATPALIMPLMHYVYENELDMS--------QMKLLILGADSCPAEDFKTLLARFGQ 4894 Query: 310 VTCHRLLERYGMTEFVMALSNPLHG---ARKEGTV--GKPLPRVEAKIIMDDGTETKDGV 474 R++ YG+TE + S A + GTV GKPLP + ++ GV Sbjct: 4895 KM--RIINSYGVTEACIDTSYYEETDVTAIRSGTVPIGKPLPNMTMYVVDAHLNLQPVGV 4952 Query: 475 -GELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNA 633 GELCI + + Y RPE+T E F+ F ++TGD DG LGR + Sbjct: 4953 VGELCIGGAGVARGYLNRPELTEEKFVPNPFAPGERLYRTGDLAKWRADGNVEFLGRNDH 5012 Query: 634 DI 639 + Sbjct: 5013 QV 5014 Score = 45.4 bits (106), Expect = 1e-04 Identities = 41/150 (27%), Positives = 64/150 (42%), Gaps = 16/150 (10%) Frame = +1 Query: 238 AKQLRLMMCGSSALPSPLMKR-----WEEVTCHRLLERYGMTEFVMA----LSNPLHGAR 390 A +R + G LP+ L K+ E V ++ YG TE V+ L +P + Sbjct: 714 ASSIRRFIVGGENLPTKLAKQIYDHFGENV---QIFNEYGPTETVVGCMIYLYDPQTTTQ 770 Query: 391 KEGTVGKPLPRVEAKIIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESFIDGGF- 564 + +G P V+ ++ G +GE+ I + K Y+ RPE+T E FID F Sbjct: 771 ESVPIGVPADNVQLYLLDASMQPVPVGSLGEMYIAGDGVAKGYFNRPELTKEKFIDNPFR 830 Query: 565 -----FKTGDTVTVDEDGYFIILGRTNADI 639 ++TGD DG GR + + Sbjct: 831 PGTKMYRTGDLAKWLPDGNMEYAGRMDYQV 860 Score = 43.9 bits (102), Expect = 4e-04 Identities = 27/86 (31%), Positives = 41/86 (47%), Gaps = 7/86 (8%) Frame = +1 Query: 403 VGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF----- 564 +GKP+ A I+ + GV GELC+ + + Y +PE+TAE F+ F Sbjct: 3885 IGKPIANSTAYIVDGNNQPQPIGVPGELCVGGDGVARGYVNKPELTAEKFVPNPFAPGET 3944 Query: 565 -FKTGDTVTVDEDGYFIILGRTNADI 639 ++TGD DG LGR + + Sbjct: 3945 MYRTGDLARWLPDGTIEYLGRIDQQV 3970
>MENE_BACSU (P23971) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 486 Score = 68.2 bits (165), Expect = 2e-11 Identities = 59/206 (28%), Positives = 90/206 (43%), Gaps = 3/206 (1%) Frame = +1 Query: 16 NALFAPLYSGSVVEFMPKFSVRGVWQRWCESYPKGTSKNDEAITVFTGVPTVYTRLLQGY 195 +ALF + G V +FSV V S N +T+ + V T+ LL+ Sbjct: 201 SALFKSVIYGMTVVLHQRFSVSDVLH----------SINRHEVTMISAVQTMLASLLE-- 248 Query: 196 DSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEF---VMAL 366 + + C + +R ++ G P PL++ E + + YGMTE ++ L Sbjct: 249 ------ETNRCP---ESIRCILLGGGPAPLPLLEECREKG-FPVFQSYGMTETCSQIVTL 298 Query: 367 SNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAES 546 S P K G+ GKPL E KI D GE+ +K P++ K Y+ R S Sbjct: 299 S-PEFSMEKLGSAGKPLFSCEIKIERDGQVCEPYEHGEIMVKGPNVMKSYFNRESANEAS 357 Query: 547 FIDGGFFKTGDTVTVDEDGYFIILGR 624 F G+ KTGD +D +G+ +L R Sbjct: 358 F-QNGWLKTGDLGYLDNEGFLYVLDR 382
>TYCA_BREPA (P09095) Tyrocidine synthetase 1 (Tyrocidine synthetase I)| [Includes: ATP-dependent D-phenylalanine adenylase (D-PheA) (D-phenylalanine activase); Phenylalanine racemase [ATP-hydrolyzing] (EC 5.1.1.11)] Length = 1088 Score = 67.4 bits (163), Expect = 3e-11 Identities = 61/219 (27%), Positives = 100/219 (45%), Gaps = 13/219 (5%) Frame = +1 Query: 22 LFAPLYSGSVVEFMPKFSVRGVWQRWCESYPKGTSKNDEAITVFTGVPTVYTRLLQGYDS 201 +F L SG+ + + K ++ ++ S+N+ +T+ T PT T L Sbjct: 229 MFMALLSGASLYILSKQTIHDF-----AAFEHYLSENE--LTIITLPPTYLTHL------ 275 Query: 202 MNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEFVM------A 363 P++ ++ LR+M+ SA +PL+ +W++ R + YG TE + A Sbjct: 276 -TPERITS-------LRIMITAGSASSAPLVNKWKDKL--RYINAYGPTETSICATIWEA 325 Query: 364 LSNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTA 540 SN L + + +GKP+ I+ +D G GELCI L + YW RP++TA Sbjct: 326 PSNQL--SVQSVPIGKPIQNTHIYIVNEDLQLLPTGSEGELCIGGVGLARGYWNRPDLTA 383 Query: 541 ESFIDGGF------FKTGDTVTVDEDGYFIILGRTNADI 639 E F+D F ++TGD DG LGR + + Sbjct: 384 EKFVDNPFVPGEKMYRTGDLAKWLTDGTIEFLGRIDHQV 422
>AAS_ECOLI (P31119) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 719 Score = 67.0 bits (162), Expect = 5e-11 Identities = 65/223 (29%), Positives = 97/223 (43%), Gaps = 17/223 (7%) Frame = +1 Query: 7 GLFNALFAPLYSGSVVEFMP-----KFSVRGVWQRWCESYPKGTSKNDEAITVFTGVPTV 171 GL LF PL +G+ V P + V+ R C TV G T Sbjct: 420 GLTVGLFTPLLTGAEVFLYPSPLHYRIVPELVYDRSC--------------TVLFGTSTF 465 Query: 172 ---YTRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCHRLLERYG 342 Y R YD +LR ++ G+ L + W++ R+LE YG Sbjct: 466 LGHYARFANPYDFY-------------RLRYVVAGAEKLQESTKQLWQDKFGLRILEGYG 512 Query: 343 MTEFVMALSNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWK 522 +TE +S + A K GTVG+ LP ++A+++ G E G L +K P++ Y + Sbjct: 513 VTECAPVVSINVPMAAKPGTVGRILPGMDARLLSVPGIEEG---GRLQLKGPNIMNGYLR 569 Query: 523 --RPEV----TAESF---IDGGFFKTGDTVTVDEDGYFIILGR 624 +P V TAE+ ++ G++ TGD V DE G+ I GR Sbjct: 570 VEKPGVLEVPTAENVRGEMERGWYDTGDIVRFDEQGFVQIQGR 612
>AAS_ECOL6 (Q8FEA6) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 719 Score = 67.0 bits (162), Expect = 5e-11 Identities = 65/223 (29%), Positives = 97/223 (43%), Gaps = 17/223 (7%) Frame = +1 Query: 7 GLFNALFAPLYSGSVVEFMP-----KFSVRGVWQRWCESYPKGTSKNDEAITVFTGVPTV 171 GL LF PL +G+ V P + V+ R C TV G T Sbjct: 420 GLTVGLFTPLLTGAEVFLYPSPLHYRIVPELVYDRSC--------------TVLFGTSTF 465 Query: 172 ---YTRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCHRLLERYG 342 Y R YD +LR ++ G+ L + W++ R+LE YG Sbjct: 466 LGHYARFANPYDFY-------------RLRYVVAGAEKLQESTKQLWQDKFGLRILEGYG 512 Query: 343 MTEFVMALSNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWK 522 +TE +S + A K GTVG+ LP ++A+++ G E G L +K P++ Y + Sbjct: 513 VTECAPVVSINVPMAAKPGTVGRILPGMDARLLSVPGIEEG---GRLQLKGPNIMNGYLR 569 Query: 523 --RPEV----TAESF---IDGGFFKTGDTVTVDEDGYFIILGR 624 +P V TAE+ ++ G++ TGD V DE G+ I GR Sbjct: 570 VEKPGVLEVPTAENVRGEMERGWYDTGDIVRFDEQGFVQIQGR 612
>AAS_ECO57 (Q8X6J8) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 719 Score = 67.0 bits (162), Expect = 5e-11 Identities = 65/223 (29%), Positives = 97/223 (43%), Gaps = 17/223 (7%) Frame = +1 Query: 7 GLFNALFAPLYSGSVVEFMP-----KFSVRGVWQRWCESYPKGTSKNDEAITVFTGVPTV 171 GL LF PL +G+ V P + V+ R C TV G T Sbjct: 420 GLTVGLFTPLLTGAEVFLYPSPLHYRIVPELVYDRSC--------------TVLFGTSTF 465 Query: 172 ---YTRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCHRLLERYG 342 Y R YD +LR ++ G+ L + W++ R+LE YG Sbjct: 466 LGHYARFANPYDFY-------------RLRYVVAGAEKLQESTKQLWQDKFGLRILEGYG 512 Query: 343 MTEFVMALSNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWK 522 +TE +S + A K GTVG+ LP ++A+++ G E G L +K P++ Y + Sbjct: 513 VTECAPVVSINVPMAAKPGTVGRILPGMDARLLSVPGIEEG---GRLQLKGPNIMNGYLR 569 Query: 523 --RPEV----TAESF---IDGGFFKTGDTVTVDEDGYFIILGR 624 +P V TAE+ ++ G++ TGD V DE G+ I GR Sbjct: 570 VEKPGVLEVPTAENVRGEMERGWYDTGDIVRFDEQGFVQIQGR 612
>AAS_SHIFL (Q83JV7) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 719 Score = 66.2 bits (160), Expect = 8e-11 Identities = 54/176 (30%), Positives = 83/176 (47%), Gaps = 12/176 (6%) Frame = +1 Query: 133 DEAITVFTGVPTV---YTRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRW 303 D + TV G T Y R YD +LR ++ G+ L + W Sbjct: 453 DRSCTVLFGTSTFLGHYARFANPYDFY-------------RLRYVVAGAEKLQESTKQLW 499 Query: 304 EEVTCHRLLERYGMTEFVMALSNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGVGEL 483 ++ R+LE YG+TE +S + A K GTVG+ LP ++A+++ G E G L Sbjct: 500 QDKFGLRILEGYGVTECAPVVSINVPMAAKPGTVGRILPGMDARLLSVPGIEEG---GRL 556 Query: 484 CIKSPSLFKEYWK--RPEV----TAESF---IDGGFFKTGDTVTVDEDGYFIILGR 624 +K P++ Y + +P V TAE+ ++ G++ TGD V DE G+ I GR Sbjct: 557 QLKGPNIMNGYLRVEKPGVLEVPTAENVRGEMERGWYDTGDIVRFDEQGFVQIQGR 612
>AAS_SALTI (Q8Z406) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 719 Score = 65.9 bits (159), Expect = 1e-10 Identities = 63/223 (28%), Positives = 94/223 (42%), Gaps = 17/223 (7%) Frame = +1 Query: 7 GLFNALFAPLYSGSVVEFMP-----KFSVRGVWQRWCESYPKGTSKNDEAITVFTGVPTV 171 GL LF PL +G+ V P + V+ R C TV G T Sbjct: 420 GLTVGLFTPLLTGAEVFLYPSPLHYRIVPELVYDRNC--------------TVLFGTSTF 465 Query: 172 ---YTRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCHRLLERYG 342 Y R YD +LR ++ G+ L + W++ R+LE YG Sbjct: 466 LGNYARFANPYDFY-------------RLRYVVAGAEKLQESTKQLWQDKFGLRILEGYG 512 Query: 343 MTEFVMALSNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWK 522 +TE +S + A K GTVG+ LP ++A+++ G E G L +K P++ Y + Sbjct: 513 VTECAPVVSINVPMAAKPGTVGRILPGMDARLLAVPGIENG---GRLQLKGPNIMNGYLR 569 Query: 523 --RPEV-------TAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 +P V A + G++ TGD V DE+G+ I GR Sbjct: 570 VEKPGVLEVPSAENARGETERGWYDTGDIVRFDENGFVQIQGR 612
>AAS_SALPA (Q5PEN7) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 719 Score = 65.9 bits (159), Expect = 1e-10 Identities = 63/223 (28%), Positives = 94/223 (42%), Gaps = 17/223 (7%) Frame = +1 Query: 7 GLFNALFAPLYSGSVVEFMP-----KFSVRGVWQRWCESYPKGTSKNDEAITVFTGVPTV 171 GL LF PL +G+ V P + V+ R C TV G T Sbjct: 420 GLTVGLFTPLLTGAEVFLYPSPLHYRIVPELVYDRNC--------------TVLFGTSTF 465 Query: 172 ---YTRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCHRLLERYG 342 Y R YD +LR ++ G+ L + W++ R+LE YG Sbjct: 466 LGNYARFANPYDFY-------------RLRYVVAGAEKLQESTKQLWQDKFGLRILEGYG 512 Query: 343 MTEFVMALSNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWK 522 +TE +S + A K GTVG+ LP ++A+++ G E G L +K P++ Y + Sbjct: 513 VTECAPVVSINVPMAAKPGTVGRILPGMDARLLAVPGIENG---GRLQLKGPNIMNGYLR 569 Query: 523 --RPEV-------TAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 +P V A + G++ TGD V DE+G+ I GR Sbjct: 570 VEKPGVLEVPSAENARGETERGWYDTGDIVRFDENGFVQIQGR 612
>AAS_SALTY (Q8ZMA4) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 719 Score = 64.7 bits (156), Expect = 2e-10 Identities = 62/223 (27%), Positives = 94/223 (42%), Gaps = 17/223 (7%) Frame = +1 Query: 7 GLFNALFAPLYSGSVVEFMP-----KFSVRGVWQRWCESYPKGTSKNDEAITVFTGVPTV 171 GL LF PL +G+ V P + V+ R C TV G T Sbjct: 420 GLTVGLFTPLLTGAEVFLYPSPLHYRIVPELVYDRNC--------------TVLFGTSTF 465 Query: 172 ---YTRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCHRLLERYG 342 Y R YD +LR ++ G+ L + W++ R+LE YG Sbjct: 466 LGNYARFANPYDFY-------------RLRYVVAGAEKLQESTKQLWQDKFGLRILEGYG 512 Query: 343 MTEFVMALSNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWK 522 +TE +S + A K GTVG+ LP ++A+++ G E G L +K P++ Y + Sbjct: 513 VTECAPVVSINVPMAAKPGTVGRILPGMDARLLAVPGIENG---GRLQLKGPNIMNGYLR 569 Query: 523 --RPEV-------TAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 +P V + + G++ TGD V DE+G+ I GR Sbjct: 570 VEKPGVLEVPSAENSRGETERGWYDTGDIVRFDENGFVQIQGR 612
>LUCI_LUCMI (Q26304) Luciferin 4-monooxygenase (EC 1.13.12.7) (Luciferase)| Length = 548 Score = 64.3 bits (155), Expect = 3e-10 Identities = 44/122 (36%), Positives = 59/122 (48%), Gaps = 8/122 (6%) Frame = +1 Query: 283 SPLMKRWEEVTCHR-----LLERYGMTEFVMALSNPLHGARKEGTVGKPLPRVEAKIIMD 447 +PL K E R + + YG+TE A G K G GK +P + K+I D Sbjct: 319 APLAKEVGEAVARRFNLPGVRQGYGLTETTSAFIITPEGDDKPGASGKVVPLFKVKVI-D 377 Query: 448 DGTETKDGV---GELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIIL 618 T+ GV GE+C+K PSL Y PE T E+ + G+ TGD DED +F I+ Sbjct: 378 LDTKKTLGVNRRGEICVKGPSLMLGYSNNPEATRETIDEEGWLHTGDIGYYDEDEHFFIV 437 Query: 619 GR 624 R Sbjct: 438 DR 439
>CAIC_SALTY (Q8ZRX4) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 517 Score = 63.9 bits (154), Expect = 4e-10 Identities = 40/106 (37%), Positives = 59/106 (55%), Gaps = 5/106 (4%) Frame = +1 Query: 322 RLLERYGMTEFVMALSNPLHG-ARKEGTVGKPLPRVEAKIIMDDGTETKDG-VGELCIKS 495 RLL YGMTE ++ + G R+ ++G+ EA+I D G +GE+CIK Sbjct: 314 RLLTSYGMTETIVGIIGDRPGDKRRWPSIGRVGFSYEAEIRDDQNRPLPAGEIGEICIKG 373 Query: 496 ---PSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 ++FKEY+ +PE TA++ G+ TGD+ DEDGYF + R Sbjct: 374 IPGKTIFKEYYMQPEATAKALEPEGWLHTGDSGYQDEDGYFYFVDR 419
>AAS_YERPS (Q667F1) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 718 Score = 63.9 bits (154), Expect = 4e-10 Identities = 65/225 (28%), Positives = 98/225 (43%), Gaps = 19/225 (8%) Frame = +1 Query: 7 GLFNALFAPLYSGSVVEFMP-----KFSVRGVWQRWCESYPKGTSKNDEAITVFTGVPTV 171 GL LF PL +GS V P + V+ R C TV G T Sbjct: 420 GLTVGLFTPLMTGSRVFLYPSPLHYRVVPELVYDRNC--------------TVLFGTSTF 465 Query: 172 ---YTRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCHRLLERYG 342 Y R YD ++R ++ G+ L + W++ R+LE YG Sbjct: 466 LGNYARFAHPYDFA-------------RVRYVVAGAEKLAESTKQIWQDKFGIRILEGYG 512 Query: 343 MTEF--VMALSNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEY 516 +TE V+A++ P+ A K TVG+ LP +EA++I G G L ++ P++ + Y Sbjct: 513 VTECAPVVAINVPM--AAKVNTVGRILPGMEARLINVPGIAQG---GRLQLRGPNIMRGY 567 Query: 517 WK--RPEV-------TAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 + P V A+ +D ++ TGD VT+DE G+ I GR Sbjct: 568 LRVENPGVLEQPSAENAQGELDANWYDTGDIVTLDEQGFCAIRGR 612
>AAS_YERPE (Q74RZ6) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 718 Score = 63.9 bits (154), Expect = 4e-10 Identities = 65/225 (28%), Positives = 98/225 (43%), Gaps = 19/225 (8%) Frame = +1 Query: 7 GLFNALFAPLYSGSVVEFMP-----KFSVRGVWQRWCESYPKGTSKNDEAITVFTGVPTV 171 GL LF PL +GS V P + V+ R C TV G T Sbjct: 420 GLTVGLFTPLMTGSRVFLYPSPLHYRVVPELVYDRNC--------------TVLFGTSTF 465 Query: 172 ---YTRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCHRLLERYG 342 Y R YD ++R ++ G+ L + W++ R+LE YG Sbjct: 466 LGNYARFAHPYDFA-------------RVRYVVAGAEKLAESTKQIWQDKFGIRILEGYG 512 Query: 343 MTEF--VMALSNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEY 516 +TE V+A++ P+ A K TVG+ LP +EA++I G G L ++ P++ + Y Sbjct: 513 VTECAPVVAINVPM--AAKVNTVGRILPGMEARLINVPGIAQG---GRLQLRGPNIMRGY 567 Query: 517 WK--RPEV-------TAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 + P V A+ +D ++ TGD VT+DE G+ I GR Sbjct: 568 LRVENPGVLEQPSAENAQGELDANWYDTGDIVTLDEQGFCAIRGR 612
>LUCI_LUCLA (Q01158) Luciferin 4-monooxygenase (EC 1.13.12.7) (Luciferase)| Length = 548 Score = 63.5 bits (153), Expect = 5e-10 Identities = 42/121 (34%), Positives = 59/121 (48%), Gaps = 7/121 (5%) Frame = +1 Query: 283 SPLMKRWEEVTCHR-----LLERYGMTEFVMALSNPLHGARKEGTVGKPLPRVEAKIIMD 447 +PL K E R + + YG+TE A+ G K G GK +P +AK+I Sbjct: 319 APLSKEIGEAVARRFNLPGVRQGYGLTETTSAIIITPEGDDKPGASGKVVPLFKAKVIDL 378 Query: 448 DGTET--KDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILG 621 D +T + GE+C+K P L K Y PE T E + G+ TGD DE+ +F I+ Sbjct: 379 DTKKTLGPNRRGEVCVKGPMLMKGYVDNPEATREIIDEEGWLHTGDIGYYDEEKHFFIVD 438 Query: 622 R 624 R Sbjct: 439 R 439
>CAIC_SALTI (Q8Z9L4) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 517 Score = 63.5 bits (153), Expect = 5e-10 Identities = 40/106 (37%), Positives = 58/106 (54%), Gaps = 5/106 (4%) Frame = +1 Query: 322 RLLERYGMTEFVMALSNPLHG-ARKEGTVGKPLPRVEAKIIMDDGTETKDG-VGELCIKS 495 RLL YGMTE ++ + G R+ ++G+ EA+I D G +GE+CIK Sbjct: 314 RLLTSYGMTETIVGIIGDRPGDKRRWPSIGRVGFSYEAEIRDDQNRPLPAGEIGEICIKG 373 Query: 496 ---PSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 ++FKEY+ +PE TA + G+ TGD+ DEDGYF + R Sbjct: 374 IPGKTIFKEYYMQPEATARALEPEGWLHTGDSGYQDEDGYFYFVDR 419
>CAIC_SALPA (Q5PIL0) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 517 Score = 63.5 bits (153), Expect = 5e-10 Identities = 40/106 (37%), Positives = 58/106 (54%), Gaps = 5/106 (4%) Frame = +1 Query: 322 RLLERYGMTEFVMALSNPLHG-ARKEGTVGKPLPRVEAKIIMDDGTETKDG-VGELCIKS 495 RLL YGMTE ++ + G R+ ++G+ EA+I D G +GE+CIK Sbjct: 314 RLLTSYGMTETIVGIIGDRPGDKRRWPSIGRVGFSYEAEIRDDQNRPLPAGEIGEICIKG 373 Query: 496 ---PSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 ++FKEY+ +PE TA + G+ TGD+ DEDGYF + R Sbjct: 374 IPGKTIFKEYYMQPEATARALEPEGWLHTGDSGYQDEDGYFYFVDR 419
>GRSA_BREBE (P0C062) Gramicidin S synthetase 1 (Gramicidin S synthetase I)| [Includes: ATP-dependent D-phenylalanine adenylase (D-PheA) (D-phenylalanine activase); Phenylalanine racemase [ATP-hydrolyzing] (EC 5.1.1.11)] Length = 1098 Score = 63.5 bits (153), Expect = 5e-10 Identities = 56/183 (30%), Positives = 82/183 (44%), Gaps = 13/183 (7%) Frame = +1 Query: 130 NDEAITVFTGVPTVYTRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEE 309 N + ITV T PT L D + S L+ GS+ PS L+ +W+E Sbjct: 270 NQKEITVITLPPTYVVHL---------DPERILSIQT----LITAGSATSPS-LVNKWKE 315 Query: 310 VTCHRLLERYGMTEFVMALSNPLHGARKEGT-----VGKPLPRVEAKIIMDDGTETKD-- 468 + + YG TE + + + A KE T +G P+ + I+ D+ + K Sbjct: 316 KVTY--INAYGPTETTICATTWV--ATKETTGHSVPIGAPIQNTQIYIV-DENLQLKSVG 370 Query: 469 GVGELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTN 630 GELCI L + YWKRPE+T++ F+D F +KTGD DG LGR + Sbjct: 371 EAGELCIGGEGLARGYWKRPELTSQKFVDNPFVPGEKLYKTGDQARWLPDGNIEYLGRID 430 Query: 631 ADI 639 + Sbjct: 431 NQV 433
>CAIC_SALCH (Q57TJ0) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 517 Score = 62.8 bits (151), Expect = 8e-10 Identities = 40/106 (37%), Positives = 58/106 (54%), Gaps = 5/106 (4%) Frame = +1 Query: 322 RLLERYGMTEFVMALSNPLHG-ARKEGTVGKPLPRVEAKIIMDDGTETKDG-VGELCIKS 495 RLL YGMTE ++ + G R+ ++G+ EA+I D G +GE+CIK Sbjct: 314 RLLTSYGMTETIVGIIGDRPGDKRRWPSIGRVGFSYEAEIRDDQNRPLPAGEIGEICIKG 373 Query: 496 ---PSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 ++FKEY+ +PE TA + G+ TGD+ DEDGYF + R Sbjct: 374 IPGKTIFKEYYMQPEATAGALEPEGWLHTGDSGYQDEDGYFYFVDR 419
>AAS_PHOLL (Q7N7A9) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 639 Score = 62.8 bits (151), Expect = 8e-10 Identities = 52/146 (35%), Positives = 75/146 (51%), Gaps = 11/146 (7%) Frame = +1 Query: 220 SACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEF--VMALSNPLHGARK 393 SA Y +LR ++ G L + W++ R+LE YGMTE V+AL+ P+ K Sbjct: 472 SAHPYDFARLRCVIAGIEKLAENTKQIWQDKFGIRILEGYGMTECAPVIALNVPM--MAK 529 Query: 394 EGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKR--------PEVTAE-S 546 GTVG+ LP +E ++I G K G G L ++ P++ K Y + P V E Sbjct: 530 VGTVGRILPAMEFRLIPIAG--IKQG-GRLQLRGPNMMKGYLRMEDPNHLEPPAVKDEHG 586 Query: 547 FIDGGFFKTGDTVTVDEDGYFIILGR 624 I + TGD V++DE G+ ILGR Sbjct: 587 NIQFDWLDTGDIVSIDEQGFCTILGR 612
>LUCI_LUCCR (P13129) Luciferin 4-monooxygenase (EC 1.13.12.7) (Luciferase)| Length = 548 Score = 62.4 bits (150), Expect = 1e-09 Identities = 41/121 (33%), Positives = 59/121 (48%), Gaps = 7/121 (5%) Frame = +1 Query: 283 SPLMKRWEEVTCHR-----LLERYGMTEFVMALSNPLHGARKEGTVGKPLPRVEAKIIMD 447 +PL K E R + + YG+TE A+ G K G GK +P +AK+I Sbjct: 319 APLSKEVGEAVARRFNLPGVRQGYGLTETTSAIIITPEGDDKPGASGKVVPLFKAKVIDL 378 Query: 448 DGTET--KDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILG 621 D ++ + GE+C+K P L K Y PE T E + G+ TGD DE+ +F I+ Sbjct: 379 DTKKSLGPNRRGEVCVKGPMLMKGYVNNPEATKELIDEEGWLHTGDIGYYDEEKHFFIVD 438 Query: 622 R 624 R Sbjct: 439 R 439
>FADK_ECOLI (P38135) Short-chain-fatty-acid--CoA ligase (EC 6.2.1.-) (Acyl-CoA| synthetase) Length = 548 Score = 62.4 bits (150), Expect = 1e-09 Identities = 46/149 (30%), Positives = 74/149 (49%), Gaps = 5/149 (3%) Frame = +1 Query: 193 YDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEF----VM 360 YD +N ++ +A LR +CG + +P + + ++ +LL YG TE V+ Sbjct: 289 YDLLNVLEKQPADLSA--LRFFLCGGTTIPKKVARECQQRGI-KLLSVYGSTESSPHAVV 345 Query: 361 ALSNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVT 537 L +PL +R T G VE K++ D G GE + P++F Y+ PE+T Sbjct: 346 NLDDPL--SRFMHTDGYAAAGVEIKVVDDARKTLPPGCEGEEASRGPNVFMGYFDEPELT 403 Query: 538 AESFIDGGFFKTGDTVTVDEDGYFIILGR 624 A + + G++ +GD +DE GY I GR Sbjct: 404 ARALDEEGWYYSGDLCRMDEAGYIKITGR 432
>GRSA_ANEMI (P0C061) Gramicidin S synthetase 1 (Gramicidin S synthetase I)| [Includes: ATP-dependent D-phenylalanine adenylase (D-PheA) (D-phenylalanine activase); Phenylalanine racemase [ATP-hydrolyzing] (EC 5.1.1.11)] Length = 1098 Score = 62.0 bits (149), Expect = 1e-09 Identities = 53/181 (29%), Positives = 79/181 (43%), Gaps = 11/181 (6%) Frame = +1 Query: 130 NDEAITVFTGVPTVYTRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEE 309 N + ITV T PT L D + S L+ GS+ PS L+ +W+E Sbjct: 270 NQKEITVITLPPTYVVHL---------DPERILSIQT----LITAGSATSPS-LVNKWKE 315 Query: 310 VTCHRLLERYGMTEFVMALSNPLHGARKEG---TVGKPLPRVEAKIIMDDGTETKD--GV 474 + + YG TE + + + G +G P+ + I+ D+ + K Sbjct: 316 KVTY--INAYGPTETTICATTWVATKETIGHSVPIGAPIQNTQIYIV-DENLQLKSVGEA 372 Query: 475 GELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNAD 636 GELCI L + YWKRPE+T++ F+D F +KTGD DG LGR + Sbjct: 373 GELCIGGEGLARGYWKRPELTSQKFVDNPFVPGEKLYKTGDQARWLSDGNIEYLGRIDNQ 432 Query: 637 I 639 + Sbjct: 433 V 433
>MENE_OCEIH (Q8ENZ7) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 480 Score = 61.6 bits (148), Expect = 2e-09 Identities = 54/212 (25%), Positives = 92/212 (43%), Gaps = 2/212 (0%) Frame = +1 Query: 1 VHGLFNALFAPLYSGSVVEFMPKFSVRGVWQRWCESYPKGTSKNDEAITVFTGVPTVYTR 180 V GL L + +Y G + + KF V V + D +T+ + V + R Sbjct: 198 VSGLSTMLKSVIY-GMPIYVLEKFEVEKVHN----------AIMDRKVTIVSVVTVMVQR 246 Query: 181 LLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEFVM 360 L++ + + R M+ G P L+++ ++ + + YGMTE Sbjct: 247 LIKRLGN---------HHYPNDFRCMLLGGGPAPKSLLEQ-AKLKNIPVFQSYGMTETSS 296 Query: 361 ALSN--PLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEV 534 + P +K G+ GKPL + KI ++ + +GE+ +K P + K Y+KR E Sbjct: 297 QIVTLTPEDALKKIGSAGKPLFPAQLKIAHNENNPNQ--IGEILVKGPMVTKGYYKRAET 354 Query: 535 TAESFIDGGFFKTGDTVTVDEDGYFIILGRTN 630 E F + + TGD +DE GY ++ R N Sbjct: 355 NKEVF-ENNWLHTGDMGYLDEQGYLYVVDRRN 385
>GRSB_ANEMI (P0C063) Gramicidin S synthetase 2 (Gramicidin S synthetase II)| [Includes: ATP-dependent proline adenylase (ProA) (Proline activase); ATP-dependent valine adenylase (ValA) (Valine activase); ATP-dependent ornithine adenylase (OrnA) (Ornithine Length = 4450 Score = 61.6 bits (148), Expect = 2e-09 Identities = 60/223 (26%), Positives = 97/223 (43%), Gaps = 12/223 (5%) Frame = +1 Query: 7 GLFNALFAPLYSGSVVEFMPKFSVRGVWQRWCESYPKGTSK--NDEAITVFTGVPTVYTR 180 G +LFAP+ +G+ +PK P K E IT + GVP++++ Sbjct: 3782 GFVASLFAPILAGAT-SVLPKEEEA--------KDPVALKKLIASEEITHYYGVPSLFSA 3832 Query: 181 LLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCH-RLLERYGMTE-- 351 +L S + + LR + G LP+ ++K+ +E + YG TE Sbjct: 3833 ILDVSSSKD----------LQNLRCVTLGGEKLPAQIVKKIKEKNKEIEVNNEYGPTENS 3882 Query: 352 FVMALSNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRP 528 V + + +E T+G+PL V+ I+ + GV GELCI L + Y +P Sbjct: 3883 VVTTIMRDIQ-VEQEITIGRPLSNVDVYIVNCNHQLQPVGVVGELCIGGQGLARGYLNKP 3941 Query: 529 EVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNADI 639 E+TA+ F+ F +KTGD DG +GR + + Sbjct: 3942 ELTADKFVVNPFVPGERMYKTGDLAKWRSDGMIEYVGRVDEQV 3984 Score = 50.4 bits (119), Expect = 4e-06 Identities = 50/182 (27%), Positives = 77/182 (42%), Gaps = 16/182 (8%) Frame = +1 Query: 142 ITVFTGVPTVYTRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALP----SPLMKRWEE 309 IT+F P + L++ D QL++++ GS + L+ R+ Sbjct: 2776 ITIFEATPALVIPLMEYIYEQKLD--------ISQLQILIVGSDSCSMEDFKTLVSRFGS 2827 Query: 310 VTCHRLLERYGMTEFVMALS---NPLHGARKEGTV--GKPLPRVEAKIIMDDGTETKDGV 474 R++ YG+TE + S PL GTV GKP ++ I+ GV Sbjct: 2828 TI--RIVNSYGVTEACIDSSYYEQPLSSLHVTGTVPIGKPYANMKMYIMNQYLQIQPVGV 2885 Query: 475 -GELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNA 633 GELCI + + Y RP++TAE F+ F ++TGD DG LGR + Sbjct: 2886 IGELCIGGAGVARGYLNRPDLTAEKFVPNPFVPGEKLYRTGDLARWMPDGNVEFLGRNDH 2945 Query: 634 DI 639 + Sbjct: 2946 QV 2947 Score = 33.9 bits (76), Expect = 0.42 Identities = 25/86 (29%), Positives = 37/86 (43%), Gaps = 7/86 (8%) Frame = +1 Query: 403 VGKPLPRVEAKIIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESFIDGGF----- 564 +GKP+ I+ + G VGEL I ++ + Y E+TAE F F Sbjct: 780 IGKPISNTWIYILDQEQQLQPQGIVGELYISGANVGRGYLNNQELTAEKFFADPFRPNER 839 Query: 565 -FKTGDTVTVDEDGYFIILGRTNADI 639 ++TGD DG LGR + + Sbjct: 840 MYRTGDLARWLPDGNIEFLGRADHQV 865
>LUCI_PHOPY (P08659) Luciferin 4-monooxygenase (EC 1.13.12.7) (Luciferase)| Length = 550 Score = 60.8 bits (146), Expect = 3e-09 Identities = 42/122 (34%), Positives = 58/122 (47%), Gaps = 8/122 (6%) Frame = +1 Query: 283 SPLMKRWEEVTCHR-----LLERYGMTEFVMALSNPLHGARKEGTVGKPLPRVEAKIIMD 447 +PL K E R + + YG+TE A+ G K G VGK +P EAK++ Sbjct: 317 APLSKEVGEAVAKRFHLPGIRQGYGLTETTSAILITPEGDDKPGAVGKVVPFFEAKVVDL 376 Query: 448 DGTETKDGV---GELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIIL 618 D +T GV GELC++ P + Y PE T G+ +GD DED +F I+ Sbjct: 377 DTGKTL-GVNQRGELCVRGPMIMSGYVNNPEATNALIDKDGWLHSGDIAYWDEDEHFFIV 435 Query: 619 GR 624 R Sbjct: 436 DR 437
>FAD11_MYCTU (Q10776) Putative fatty-acid--CoA ligase fadD11 (EC 6.2.1.-)| (Acyl-CoA synthetase) Length = 571 Score = 60.5 bits (145), Expect = 4e-09 Identities = 41/129 (31%), Positives = 64/129 (49%), Gaps = 2/129 (1%) Frame = +1 Query: 244 QLRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEF--VMALSNPLHGARKEGTVGKPL 417 +LR + G++ +P + + + + E +GM+E V S+P G + GTVGK L Sbjct: 299 ELRWALSGAAPIPKETLAFFAGIGIP-IAEIWGMSELSCVATASHPRDG--RLGTVGKLL 355 Query: 418 PRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDE 597 P ++ KI D GE ++ P + K Y K P TAE+ G+ TGD +D Sbjct: 356 PGLQGKIAED---------GEYLVRGPLVMKGYRKEPAKTAEAIDSDGWLHTGDVFDIDS 406 Query: 598 DGYFIILGR 624 DGY ++ R Sbjct: 407 DGYLRVVDR 415
>GRSB_BREBE (P0C064) Gramicidin S synthetase 2 (Gramicidin S synthetase II)| [Includes: ATP-dependent proline adenylase (ProA) (Proline activase); ATP-dependent valine adenylase (ValA) (Valine activase); ATP-dependent ornithine adenylase (OrnA) (Ornithine Length = 4449 Score = 59.7 bits (143), Expect = 7e-09 Identities = 60/223 (26%), Positives = 96/223 (43%), Gaps = 12/223 (5%) Frame = +1 Query: 7 GLFNALFAPLYSGSVVEFMPKFSVRGVWQRWCESYPKGTSK--NDEAITVFTGVPTVYTR 180 G +LFAP+ +G+ +PK P K E IT + GVP++++ Sbjct: 3781 GFVASLFAPILAGAT-SVLPKEEEA--------KDPVALKKLIASEEITHYYGVPSLFSA 3831 Query: 181 LLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCH-RLLERYGMTE-- 351 +L S + + LR + G LP+ ++K+ +E + YG TE Sbjct: 3832 ILDVSSSKD----------LQNLRCVTLGGEKLPAQIVKKIKEKNKEIEVNNEYGPTENS 3881 Query: 352 FVMALSNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRP 528 V + + +E T+G PL V+ I+ + GV GELCI L + Y +P Sbjct: 3882 VVTTIMRDIQ-VEQEITIGCPLSNVDVYIVNCNHQLQPVGVVGELCIGGQGLARGYLNKP 3940 Query: 529 EVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNADI 639 E+TA+ F+ F +KTGD DG +GR + + Sbjct: 3941 ELTADKFVVNPFVPGERMYKTGDLAKWRSDGMIEYVGRVDEQV 3983 Score = 50.4 bits (119), Expect = 4e-06 Identities = 50/182 (27%), Positives = 77/182 (42%), Gaps = 16/182 (8%) Frame = +1 Query: 142 ITVFTGVPTVYTRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALP----SPLMKRWEE 309 IT+F P + L++ D QL++++ GS + L+ R+ Sbjct: 2774 ITIFEATPALVIPLMEYIYEQKLD--------ISQLQILIVGSDSCSMEDFKTLVSRFGS 2825 Query: 310 VTCHRLLERYGMTEFVMALS---NPLHGARKEGTV--GKPLPRVEAKIIMDDGTETKDGV 474 R++ YG+TE + S PL GTV GKP ++ I+ GV Sbjct: 2826 TI--RIVNSYGVTEACIDSSYYEQPLSSLHVTGTVPIGKPYANMKMYIMNQYLQIQPVGV 2883 Query: 475 -GELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNA 633 GELCI + + Y RP++TAE F+ F ++TGD DG LGR + Sbjct: 2884 IGELCIGGAGVARGYLNRPDLTAEKFVPNPFVPGEKLYRTGDLARWMPDGNVEFLGRNDH 2943 Query: 634 DI 639 + Sbjct: 2944 QV 2945 Score = 33.9 bits (76), Expect = 0.42 Identities = 25/86 (29%), Positives = 37/86 (43%), Gaps = 7/86 (8%) Frame = +1 Query: 403 VGKPLPRVEAKIIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESFIDGGF----- 564 +GKP+ I+ + G VGEL I ++ + Y E+TAE F F Sbjct: 780 IGKPISNTWIYILDQEQQLQPQGIVGELYISGANVGRGYLNNQELTAEKFFADPFRPNER 839 Query: 565 -FKTGDTVTVDEDGYFIILGRTNADI 639 ++TGD DG LGR + + Sbjct: 840 MYRTGDLARWLPDGNIEFLGRADHQV 865
>AAS_ERWCT (Q6D107) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 738 Score = 59.7 bits (143), Expect = 7e-09 Identities = 45/142 (31%), Positives = 74/142 (52%), Gaps = 11/142 (7%) Frame = +1 Query: 232 YAAKQLRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEF--VMALSNPLHGARKEGTV 405 Y +LR ++ G+ L + W++ R+LE YG+TE V+A++ P+ A K +V Sbjct: 476 YDFARLRYVVAGAEKLSETTRQVWQDKFGIRILEGYGVTECAPVVAINVPM--ATKIHSV 533 Query: 406 GKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWK--RPEV-------TAESFIDG 558 G LP +E+++I G G L ++ P++ K Y + P V AE + Sbjct: 534 GLLLPEMESRLITVPGITRG---GRLQLRGPNIMKGYLRVENPGVLETPAAENAEGELQQ 590 Query: 559 GFFKTGDTVTVDEDGYFIILGR 624 G++ TGD V +DE G+ I+GR Sbjct: 591 GWYDTGDIVELDERGFCTIIGR 612
>BACC_BACLI (O68008) Bacitracin synthetase 3 (BA3) [Includes: ATP-dependent| isoleucine adenylase (IleA) (Isoleucine activase); ATP-dependent D-phenylalanine adenylase (D-PheA) (D-phenylalanine activase); ATP-dependent histidine adenylase (HisA) (Histidine Length = 6359 Score = 59.3 bits (142), Expect = 9e-09 Identities = 41/141 (29%), Positives = 65/141 (46%), Gaps = 8/141 (5%) Frame = +1 Query: 241 KQLRLMMCGSSALPSPLMKRWEEVTCHRL-LERYGMTEFVMALSNPLHGARKEGTVGKPL 417 + L++++ SA L KRW +RL + YG TE + + ++ +G P+ Sbjct: 1751 ENLKVIVSAGSACSEELAKRWSG---NRLFINAYGPTETTVCATAGIYEGSGRPHIGSPI 1807 Query: 418 PRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTG 576 ++ + GV GELC+ SL + Y RPE+TAE FI F ++TG Sbjct: 1808 ANTNVYVLDQNQKPVPTGVVGELCVGGMSLARGYLNRPELTAEKFISHPFASGERLYRTG 1867 Query: 577 DTVTVDEDGYFIILGRTNADI 639 D DG+ LGR + + Sbjct: 1868 DLARWLPDGHLEFLGRIDHQV 1888 Score = 49.7 bits (117), Expect = 7e-06 Identities = 43/145 (29%), Positives = 61/145 (42%), Gaps = 11/145 (7%) Frame = +1 Query: 238 AKQLRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEFVMALS----NPLHGARKEGTV 405 AK ++ + G A + K V +L+ YG TE + + N + + + Sbjct: 712 AKLRKIFLGGERASIPHVRKVLNHVGRDKLIHVYGPTESTVYATYYFINEIDDEAETIPI 771 Query: 406 GKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF------ 564 G PL I+ + G GV GELCI L K Y R E+TAE FI F Sbjct: 772 GSPLANTSVLIMDEAGKLLPIGVPGELCIAGDGLSKGYLNREELTAEKFIPHPFIPGERL 831 Query: 565 FKTGDTVTVDEDGYFIILGRTNADI 639 +KTGD DG +GR + + Sbjct: 832 YKTGDLAKWLPDGNIEFIGRIDHQV 856 Score = 46.2 bits (108), Expect = 8e-05 Identities = 38/148 (25%), Positives = 67/148 (45%), Gaps = 13/148 (8%) Frame = +1 Query: 235 AAKQLRLMMCGSSALPSPLMKRWEEVTCHRL--LERYGMTEFVMALSNPLHGARKEGTVG 408 + ++ ++ G L + L K E H + YG TE V+ + A + V Sbjct: 5795 SGSSIKRLIVGGEDLKTELAKEITERFHHNIEIYNEYGPTETVVGCMIYQYDAGWDRQVS 5854 Query: 409 KPLPRVEAKI---IMDDGTETKD-GV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF--- 564 P+ + + + I+D+ E + G+ GEL I + K Y +PE+T+E F+ F Sbjct: 5855 VPIGKPASNVQLYILDERQEVQPVGIAGELYISGDGVAKGYLNKPELTSEKFLPNPFLPG 5914 Query: 565 ---FKTGDTVTVDEDGYFIILGRTNADI 639 ++TGD + DG+ LGR + + Sbjct: 5915 ERMYRTGDLAKMRPDGHIEYLGRIDHQV 5942 Score = 45.4 bits (106), Expect = 1e-04 Identities = 41/173 (23%), Positives = 70/173 (40%), Gaps = 8/173 (4%) Frame = +1 Query: 145 TVFTGVPTVYTRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCHR 324 T VP+ Y LL + D + + + G S + + +E++ + Sbjct: 3231 TNLLAVPSFYLNLLDTIEQPLDDLRF----------VTVAGEGFNESLIRQHFEKLPNVK 3280 Query: 325 LLERYGMTE-FVMALSNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSP 498 L YG TE V + L ++ +G+P+ + I+ + G GELC+ Sbjct: 3281 LFNEYGPTENSVCSTRGELRKDDEKVVIGRPISNHKVYILNHNQQLLPLGTPGELCLSGE 3340 Query: 499 SLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNADI 639 L + Y RP++T E F+ F ++TGD DG LGR + + Sbjct: 3341 GLARGYLNRPDLTLEKFVPNPFAPGESMYRTGDLARFLPDGQIEYLGRIDHQV 3393 Score = 44.7 bits (104), Expect = 2e-04 Identities = 37/145 (25%), Positives = 66/145 (45%), Gaps = 14/145 (9%) Frame = +1 Query: 247 LRLMMCGSSALPSPLMKR-WEEVTCHRLLERYGMTEF----VMALSNPLH--GARKEGTV 405 LRL++ G + + ++ + + H ++ YG TE V + +P H ++ + Sbjct: 4292 LRLVVLGGEMINTRDVETFYNQYPDHVVMNHYGPTETTIGSVFKVIDPEHLDSFKECPVI 4351 Query: 406 GKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF------ 564 G P+ A ++ ++ +GV GELCI + Y RP+ T E FI+ F Sbjct: 4352 GTPIHNTNAYVLDENMKLLPEGVYGELCIAGAGVTGGYVNRPDETKEKFIENPFAPHTKM 4411 Query: 565 FKTGDTVTVDEDGYFIILGRTNADI 639 ++TGD DG + GR + + Sbjct: 4412 YRTGDLARRLSDGNIELAGRIDTQV 4436
>CAIC_PROSL (Q8GB18) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 518 Score = 58.9 bits (141), Expect = 1e-08 Identities = 36/107 (33%), Positives = 60/107 (56%), Gaps = 5/107 (4%) Frame = +1 Query: 322 RLLERYGMTEFVMALSNPLHG-ARKEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKS 495 RLL +GMTE ++ L G R+ ++G+P +A+I + +GV GE+C+K Sbjct: 315 RLLTSHGMTETIVGLIGDRPGDKRRWPSIGRPGFCYQAQIRDKQNQQVPNGVVGEICVKG 374 Query: 496 PS---LFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRT 627 + LFKEY+ RP+ T ++ G+ TGD D++G+F + R+ Sbjct: 375 EAGKTLFKEYYNRPDATEKALEPDGWLHTGDYGYRDDEGFFYFVDRS 421
>MENE_BACCZ (Q632I5) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 482 Score = 58.2 bits (139), Expect = 2e-08 Identities = 41/129 (31%), Positives = 64/129 (49%), Gaps = 3/129 (2%) Frame = +1 Query: 247 LRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEF---VMALSNPLHGARKEGTVGKPL 417 LR M+ G P PL++ E + + YGMTE + LS + K G+ GKPL Sbjct: 255 LRCMLLGGGPAPKPLLEACVEKRIP-VYQTYGMTETSSQICTLSAD-YMLMKVGSAGKPL 312 Query: 418 PRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDE 597 + + +I D GE+ +K P++ Y+ R + T E+ I G+ TGD +DE Sbjct: 313 FQCQLRIEKDGVVVPPFAEGEIVVKGPNVTGGYFNREDATRET-IQNGWLHTGDLGYLDE 371 Query: 598 DGYFIILGR 624 +G+ +L R Sbjct: 372 EGFLYVLDR 380
>DHBE_BACSU (P40871) 2,3-dihydroxybenzoate-AMP ligase (EC 6.3.2.-)| (Dihydroxybenzoic acid-activating enzyme) Length = 539 Score = 57.0 bits (136), Expect = 5e-08 Identities = 47/173 (27%), Positives = 76/173 (43%), Gaps = 5/173 (2%) Frame = +1 Query: 136 EAITVFTGVPTVYTRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVT 315 E +T+ VP + + S D S L+++ G + + +R + V Sbjct: 271 EKVTITALVPPLAMVWMDAASSRRDDLSS--------LQVLQVGGAKFSAEAARRVKAVF 322 Query: 316 CHRLLERYGMTEFVM---ALSNPLHGARKEGTVGKPL-PRVEAKIIMDDGTETKDG-VGE 480 L + +GM E ++ L +P T GKP+ P E ++ D + K G G Sbjct: 323 GCTLQQVFGMAEGLVNYTRLDDPEEII--VNTQGKPMSPYDEMRVWDDHDRDVKPGETGH 380 Query: 481 LCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADI 639 L + P + Y+K E A SF + GF++TGD V + DGY ++ GR I Sbjct: 381 LLTRGPYTIRGYYKAEEHNAASFTEDGFYRTGDIVRLTRDGYIVVEGRAKDQI 433
>MENE_BACC1 (Q72YK9) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 481 Score = 57.0 bits (136), Expect = 5e-08 Identities = 41/129 (31%), Positives = 64/129 (49%), Gaps = 3/129 (2%) Frame = +1 Query: 247 LRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEF---VMALSNPLHGARKEGTVGKPL 417 LR M+ G P PL++ E + + YGMTE + LS + K G+ GKPL Sbjct: 254 LRCMLLGGGPAPKPLLETCVEKGIP-VYQTYGMTETSSQICTLSAD-YMLTKVGSAGKPL 311 Query: 418 PRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDE 597 + + +I D GE+ +K P++ Y+ R + T E+ I G+ TGD +DE Sbjct: 312 FQCQLRIEKDGVVVPAFTEGEIVVKGPNVTGGYFNREDATRET-IQNGWLHTGDIGYLDE 370 Query: 598 DGYFIILGR 624 +G+ +L R Sbjct: 371 EGFLYVLDR 379
>CAIC_ECOL6 (Q8FLA5) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 522 Score = 56.6 bits (135), Expect = 6e-08 Identities = 38/106 (35%), Positives = 57/106 (53%), Gaps = 5/106 (4%) Frame = +1 Query: 322 RLLERYGMTEFVMALSNPLHG-ARKEGTVGKPLPRVEAKIIMDDGTETKDG-VGELCIKS 495 RLL YGMTE ++ + G R+ ++G+ EA+I D G +GE+CIK Sbjct: 319 RLLTSYGMTETIVGIIGDRPGDKRRWPSIGRAGFCYEAEIRDDHNRPLPAGELGEICIKG 378 Query: 496 ---PSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 ++FKEY+ P+ TA+ G+ TGDT DE+G+F + R Sbjct: 379 VPGKTIFKEYFLNPKATAKVLEADGWLHTGDTGYRDEEGFFYFVDR 424
>CAIC_ECO57 (Q8XA34) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 522 Score = 56.6 bits (135), Expect = 6e-08 Identities = 37/106 (34%), Positives = 57/106 (53%), Gaps = 5/106 (4%) Frame = +1 Query: 322 RLLERYGMTEFVMALSNPLHG-ARKEGTVGKPLPRVEAKIIMDDGTETKDG-VGELCIKS 495 RLL YGMTE ++ + G R+ ++G+ +A+I D G +GE+CIK Sbjct: 319 RLLTSYGMTETIVGIIGDRPGDKRRWPSIGRAGFCYDAEIRDDHNRPLPAGEIGEICIKG 378 Query: 496 ---PSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 ++FKEY+ P+ TA+ G+ TGDT DE+G+F + R Sbjct: 379 VPGKTIFKEYFLNPKATAKVLEADGWLHTGDTGYRDEEGFFYFIDR 424
>LCF4_YEAST (P47912) Long-chain-fatty-acid--CoA ligase 4 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 4) (Fatty acid activator 4) Length = 694 Score = 56.6 bits (135), Expect = 6e-08 Identities = 43/130 (33%), Positives = 61/130 (46%), Gaps = 4/130 (3%) Frame = +1 Query: 247 LRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEFVM--ALSNPLHGARKEGTVGKPLP 420 LR ++ G SA+ K + C L+ YG+TE V + P H G G + Sbjct: 423 LRFILNGGSAISIDAQKFLSNLLCPMLIG-YGLTEGVANACVLEPEHF--DYGIAGDLVG 479 Query: 421 RVEAKII--MDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVD 594 + AK++ D G K+ GEL K + EY+K PE TA +F D G+F+TGD Sbjct: 480 TITAKLVDVEDLGYFAKNNQGELLFKGAPICSEYYKNPEETAAAFTDDGWFRTGDIAEWT 539 Query: 595 EDGYFIILGR 624 G I+ R Sbjct: 540 PKGQVKIIDR 549
>LCF3_YEAST (P39002) Long-chain-fatty-acid--CoA ligase 3 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 3) (Fatty acid activator 3) Length = 694 Score = 56.6 bits (135), Expect = 6e-08 Identities = 45/130 (34%), Positives = 64/130 (49%), Gaps = 4/130 (3%) Frame = +1 Query: 247 LRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEFVM--ALSNPLHGARKEGTVGKPLP 420 L+ +M G SA+ K + V C ++ YG+TE V + P H + G VG + Sbjct: 423 LKYIMNGGSAISIDAQKFFSIVLCPMIIG-YGLTETVANACVLEPDHF--EYGIVGDLVG 479 Query: 421 RVEAKII--MDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVD 594 V AK++ D G K+ GEL +K + EY+K P TA SF G+F+TGD V Sbjct: 480 SVTAKLVDVKDLGYYAKNNQGELLLKGAPVCSEYYKNPIETAVSFTYDGWFRTGDIVEWT 539 Query: 595 EDGYFIILGR 624 G I+ R Sbjct: 540 PKGQLKIIDR 549
>BACA_BACLI (O68006) Bacitracin synthetase 1 (BA1) [Includes: ATP-dependent| isoleucine adenylase (IleA) (Isoleucine activase); ATP-dependent cysteine adenylase (CysA) (Cysteine activase); ATP-dependent leucine adenylase (LeuA) (Leucine activase); ATP-depe Length = 5255 Score = 56.6 bits (135), Expect = 6e-08 Identities = 38/115 (33%), Positives = 57/115 (49%), Gaps = 8/115 (6%) Frame = +1 Query: 319 HRLLERYGMTE-FVMALSNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIK 492 ++++ YG TE V+A S P+ + + +GKP+ V+ I+ D G GELCI Sbjct: 2397 YQIVNNYGPTENTVVATSFPIDKSHQNIPIGKPIDNVKVYILNKDLQLCPLGASGELCIA 2456 Query: 493 SPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNADI 639 L + Y RPE+T E FI F ++TGD + DG LGR + + Sbjct: 2457 GEGLARGYVNRPELTREKFIGNPFVPGERMYRTGDLAKMLPDGNIQFLGRVDQQV 2511 Score = 50.4 bits (119), Expect = 4e-06 Identities = 43/145 (29%), Positives = 62/145 (42%), Gaps = 11/145 (7%) Frame = +1 Query: 238 AKQLRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEFVMALS----NPLHGARKEGTV 405 AK +++ G A + K + V +L+ YG TE + + N + + + Sbjct: 4917 AKLRKILFGGERASIPHVRKVLDHVGRDKLIHVYGPTESTVYATYYFINEIDDEAETIPI 4976 Query: 406 GKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF------ 564 G PL I+ + G GV GELCI L K Y R E+TAE FI F Sbjct: 4977 GSPLANTSVLIMDEAGKLLPIGVPGELCIAGDGLSKGYLNREELTAEKFIPHPFIPGERL 5036 Query: 565 FKTGDTVTVDEDGYFIILGRTNADI 639 +KTGD DG +GR + + Sbjct: 5037 YKTGDLAKWLPDGNIEFIGRIDHQV 5061 Score = 48.9 bits (115), Expect = 1e-05 Identities = 39/129 (30%), Positives = 60/129 (46%), Gaps = 12/129 (9%) Frame = +1 Query: 289 LMKRWEEVTCHRLLERYGMTEF-VMALSNPLHGARKEGT----VGKPLPRVEAKIIMDDG 453 L ++ ++C+ + YG TE V A S+ + + T +G+PL I+ + Sbjct: 3425 LFHKFPNLSCN-ITNVYGPTECCVDAASHQIESGKVPQTPSIPIGRPLLNTSIYIVDKEL 3483 Query: 454 TETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFI 612 G+ GELCI + + Y RPE+TAE F+D F +KTGD DG Sbjct: 3484 RPLPVGIAGELCIAGEGVARGYVNRPELTAEKFVDHPFEPGKKMYKTGDLAMWLPDGQIE 3543 Query: 613 ILGRTNADI 639 LGR + + Sbjct: 3544 FLGRADHQV 3552 Score = 48.1 bits (113), Expect = 2e-05 Identities = 41/141 (29%), Positives = 59/141 (41%), Gaps = 11/141 (7%) Frame = +1 Query: 250 RLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEFVMALS----NPLHGARKEGTVGKPL 417 +++ G A + K V +L+ YG TE + + N + + +G PL Sbjct: 294 KILFGGERASIPHVRKVLNHVGRDKLIHVYGPTESTVYATYYFINEIDDEAETIPIGSPL 353 Query: 418 PRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTG 576 I+ + G GV GELCI L K Y R E+TAE FI F +KTG Sbjct: 354 ANTSVLIMDEAGKLVPIGVPGELCIAGDGLSKGYLNREELTAEKFIPHPFIPGERLYKTG 413 Query: 577 DTVTVDEDGYFIILGRTNADI 639 D DG +GR + + Sbjct: 414 DLAKWLPDGNIEFIGRIDHQV 434 Score = 39.7 bits (91), Expect = 0.008 Identities = 46/181 (25%), Positives = 74/181 (40%), Gaps = 13/181 (7%) Frame = +1 Query: 136 EAITVFTGVPTVYTRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSS----ALPSPLMKRW 303 E IT++ VP + Y PD + LRL++ LP+ + K + Sbjct: 1303 ERITIWNSVPAIMGMTADVY----PDNE-----LNHHLRLILLSGDWIPLQLPATIKKTF 1353 Query: 304 EEVTCHRLLERYGMTE-FVMALSNPLHGARKEGT---VGKPLPRVEAKIIMDDGTETKDG 471 + ++ G TE + ++ P+ ++ GKPL + ++ + G Sbjct: 1354 KNA---EVISLGGATEGSIWSIYYPIQKVEEDWKSIPYGKPLANQKIYVLNQNKQLCPVG 1410 Query: 472 V-GELCIKSPSLFKEYWKRPEVTAESFID----GGFFKTGDTVTVDEDGYFIILGRTNAD 636 V GEL I + Y E T SFI G +KTGD + EDGY LGR ++ Sbjct: 1411 VEGELYIGGAGVASGYIHDQEKTEHSFIQHQELGYIYKTGDYGVLKEDGYVEFLGRKDSQ 1470 Query: 637 I 639 + Sbjct: 1471 V 1471
>4CL3_ARATH (Q9S777) 4-coumarate--CoA ligase 3 (EC 6.2.1.12) (4CL 3) (At4CL3)| (4-coumaroyl-CoA synthase 3) Length = 561 Score = 56.6 bits (135), Expect = 6e-08 Identities = 58/219 (26%), Positives = 91/219 (41%), Gaps = 11/219 (5%) Frame = +1 Query: 1 VHGLFNALFAPLYSGSVVEFMPKFSVRGVWQRWCESYPKGTSKNDEAITVFTGVPTVYTR 180 ++ L + L L SG+ V M KF + + +T+ VP + Sbjct: 262 IYSLNSVLLNSLRSGATVLLMHKFEIGALLDLI----------QRHRVTIAALVPPLVIA 311 Query: 181 LLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCHRLL-ERYGMTEFV 357 L + NP + SY +R ++ G++ L L +L + YGMTE Sbjct: 312 LAK-----NP---TVNSYDLSSVRFVLSGAAPLGKELQDSLRRRLPQAILGQGYGMTEAG 363 Query: 358 MALSNPLHGAR-----KEGTVGKPLPRVEAKIIMDDGTETKDGVG-----ELCIKSPSLF 507 LS L A+ K G+ G + E K++ ET+ +G E+CI+ + Sbjct: 364 PVLSMSLGFAKEPIPTKSGSCGTVVRNAELKVVH---LETRLSLGYNQPGEICIRGQQIM 420 Query: 508 KEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 KEY PE T+ + + G+ TGD VDED I+ R Sbjct: 421 KEYLNDPEATSATIDEEGWLHTGDIGYVDEDDEIFIVDR 459
>MENE_LISIN (Q92AY8) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 467 Score = 56.6 bits (135), Expect = 6e-08 Identities = 37/102 (36%), Positives = 53/102 (51%), Gaps = 2/102 (1%) Frame = +1 Query: 325 LLERYGMTEFVMALSN--PLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSP 498 L++ +GMTE + P K G+ GK L E KI D GE+ +K P Sbjct: 275 LVQSFGMTETASQIVTLPPKDALNKIGSSGKALFPAEVKIADD---------GEILLKGP 325 Query: 499 SLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 S+ Y + TA++FID G+FKTGD +DE+G+ +L R Sbjct: 326 SITPGYLHNEKATAKAFID-GWFKTGDIGYLDEEGFLFVLER 366
>MENE_BACHK (Q6HC29) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 482 Score = 56.6 bits (135), Expect = 6e-08 Identities = 40/129 (31%), Positives = 64/129 (49%), Gaps = 3/129 (2%) Frame = +1 Query: 247 LRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEF---VMALSNPLHGARKEGTVGKPL 417 LR M+ G P PL++ + + + YGMTE + LS + K G+ GKPL Sbjct: 255 LRCMLLGGGPAPKPLLETCVDKGIP-VYQTYGMTETSSQICTLSAD-YMLTKVGSAGKPL 312 Query: 418 PRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDE 597 + + +I D GE+ +K P++ Y+ R + T E+ I G+ TGD +DE Sbjct: 313 FQCQLRIEKDGVVVPPFAEGEIVVKGPNVTGGYFNREDATRET-IQNGWLHTGDLGYLDE 371 Query: 598 DGYFIILGR 624 +G+ +L R Sbjct: 372 EGFLYVLDR 380
>MENE_BACCR (Q816I1) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 482 Score = 56.2 bits (134), Expect = 8e-08 Identities = 41/129 (31%), Positives = 64/129 (49%), Gaps = 3/129 (2%) Frame = +1 Query: 247 LRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEF---VMALSNPLHGARKEGTVGKPL 417 LR M+ G P PL++ E + + YGMTE + LS + K G+ GKPL Sbjct: 255 LRCMLLGGGPAPKPLLEACVEKGIP-VYQTYGMTETSSQICTLSAD-YMLTKVGSAGKPL 312 Query: 418 PRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDE 597 + + +I D GE+ +K P++ Y+ R + T E+ I G+ TGD +DE Sbjct: 313 FQCQLRIEKDGVVVPPLVEGEIVVKGPNVTGGYFNREDATRET-IQNGWLHTGDLGYLDE 371 Query: 598 DGYFIILGR 624 +G+ +L R Sbjct: 372 EGFLYVLDR 380
>LGRB_BREPA (Q70LM6) Linear gramicidin synthetase subunit B [Includes:| ATP-dependent alanine adenylase (AlaA) (Alanine activase); ATP-dependent D-leucine adenylase (D-LeuA) (D-leucine activase); Leucine racemase [ATP-hydrolyzing] (EC 5.1.1.-); ATP-depende Length = 5162 Score = 56.2 bits (134), Expect = 8e-08 Identities = 50/175 (28%), Positives = 75/175 (42%), Gaps = 13/175 (7%) Frame = +1 Query: 154 TGVPTVYTRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCHRLLE 333 T V V + L+ D + QQ + LR + A+PS L+ + E +LE Sbjct: 692 THVNFVPSMLIPFVDYVRDQQQES------PLRYIFAAGEAMPSELVGKVYEALPGVILE 745 Query: 334 R-YGMTEFVMALSNPLHGARKEGT-----VGKPLPRVEAKIIMDDGTETKDGV-GELCIK 492 YG TE + + + K+ +GKPL ++ I+ G GV GELCI Sbjct: 746 NIYGPTESTIYATK--YSLAKDSQDVLVPIGKPLANIQTHIVNKHGQLQPVGVPGELCIA 803 Query: 493 SPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNADI 639 SL + YW +T E F+ F ++TGD +DG LGR + + Sbjct: 804 GASLARGYWNNEALTNEKFVPHPFAAGQRMYRTGDLARYRQDGNIEYLGRIDHQV 858 Score = 48.9 bits (115), Expect = 1e-05 Identities = 35/118 (29%), Positives = 57/118 (48%), Gaps = 13/118 (11%) Frame = +1 Query: 325 LLERYGMTEFVMALSN---PLHGARKEG-TVGKPLPRVEAKIIMDDGTETKDGV-GELCI 489 L+ +YG TE + + P+ G R+ T+G+P+ V ++ ++ GV GEL I Sbjct: 1801 LVNQYGPTENTVVATAGAVPVLGERESAPTIGRPIDNVSVYVLDENRQPVPVGVVGELYI 1860 Query: 490 KSPSLFKEYWKRPEVTAESFIDGGF--------FKTGDTVTVDEDGYFIILGRTNADI 639 SL + Y RP++T SF+ F ++TGD V DG +GR + + Sbjct: 1861 GGKSLARGYRNRPDLTEASFVPNPFSPIEGARMYRTGDLVRYAADGSIEFIGRADDQV 1918 Score = 47.0 bits (110), Expect = 5e-05 Identities = 31/95 (32%), Positives = 46/95 (48%), Gaps = 9/95 (9%) Frame = +1 Query: 382 GARKEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFI-- 552 GA+ E T+G+PL +A ++ G+ GEL + L + Y KRP++TAE F+ Sbjct: 3339 GAKTEPTIGRPLANTQAYVLDAKLQPVPLGLPGELYLGGDGLARGYLKRPKMTAERFLPN 3398 Query: 553 ------DGGFFKTGDTVTVDEDGYFIILGRTNADI 639 D + TGD V DG LGR + + Sbjct: 3399 PFHPDPDARMYSTGDLVRYLPDGQLEYLGRIDHQV 3433 Score = 44.7 bits (104), Expect = 2e-04 Identities = 37/144 (25%), Positives = 62/144 (43%), Gaps = 13/144 (9%) Frame = +1 Query: 247 LRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTE-FVMALSNPLHGARKEG---TVGKP 414 +R ++ G + P +K+ E+ ++ YG TE NP+ + +G+P Sbjct: 4350 VRQLLVGGDIVSVPHVKKALEIAGLTVINGYGPTENTTFTCCNPVTVMPESAHTFPIGRP 4409 Query: 415 LPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF--------F 567 + A ++ GV GEL I L + Y RP++TAE F+ F + Sbjct: 4410 IKNTTAYVLDRHMQPVPIGVTGELYIGGDGLAEGYLNRPDLTAERFVPNPFATDQAARLY 4469 Query: 568 KTGDTVTVDEDGYFIILGRTNADI 639 +TGD V DG +GR + + Sbjct: 4470 RTGDLVRYLPDGLIEFIGRLDNQV 4493
>ACSL1_RAT (P18163) Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 1) (LACS 1) (Long-chain-fatty-acid--CoA ligase, liver isozyme) Length = 699 Score = 55.8 bits (133), Expect = 1e-07 Identities = 35/114 (30%), Positives = 55/114 (48%), Gaps = 2/114 (1%) Frame = +1 Query: 244 QLRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEFVMALSNPLHGARKEGTVGKPLPR 423 ++RLM+ G++ + + ++ + E YG TE L G G VG P+P Sbjct: 428 KVRLMITGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLSLPGDWTAGHVGAPMPC 487 Query: 424 VEAKII--MDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGD 579 K++ D + G GE+C+K ++FK Y K P TAE+ G+ TGD Sbjct: 488 NYIKLVDVEDMNYQAAKGEGEVCVKGANVFKGYLKDPARTAEALDKDGWLHTGD 541
>ACSL1_CAVPO (Q9JID6) Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 1) (LACS 1) (Palmitoyl-CoA ligase) Length = 698 Score = 55.8 bits (133), Expect = 1e-07 Identities = 35/114 (30%), Positives = 56/114 (49%), Gaps = 2/114 (1%) Frame = +1 Query: 244 QLRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEFVMALSNPLHGARKEGTVGKPLPR 423 ++RLM+ G++ + + ++ + E YG TE S + G G VG P+P Sbjct: 427 KVRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCSLSVPGDWTAGHVGAPMPC 486 Query: 424 VEAKIIMDDGTE--TKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGD 579 K++ + G GE+C+K P++FK Y K P TAE+ G+ TGD Sbjct: 487 NFIKLVDVEEMNYMAAMGEGEVCVKGPNVFKGYLKDPAKTAEALDKDGWLHTGD 540
>4CL2_ORYSA (Q42982) 4-coumarate--CoA ligase 2 (EC 6.2.1.12) (4CL 2)| (4-coumaroyl-CoA synthase 2) Length = 569 Score = 55.8 bits (133), Expect = 1e-07 Identities = 59/223 (26%), Positives = 96/223 (43%), Gaps = 15/223 (6%) Frame = +1 Query: 1 VHGLFNALFAPLYSGSVVEFMPKF---SVRGVWQRWCESYPKGTSKNDEAITVFTGVPTV 171 + L + L + +G+ V MP+F ++ G +RW +TV VP + Sbjct: 268 IFSLNSVLLCAVRAGAAVALMPRFEMGAMLGAIERW-------------RVTVAAVVPPL 314 Query: 172 YTRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCHRLLER----- 336 L + NP + + +R+++ G++ PL K E+ RL + Sbjct: 315 VLALAK-----NPFVER---HDLSSIRIVLSGAA----PLGKELEDALRARLPQAIFGQG 362 Query: 337 YGMTEFVMALSNPLHGAR-----KEGTVGKPLPRVEAKIIMDDGTET--KDGVGELCIKS 495 YGMTE LS A+ K G+ G + E K++ D + ++ GE+CI+ Sbjct: 363 YGMTEAGPVLSMCPAFAKEPTPAKSGSCGTVVRNAELKVVDPDTGFSLGRNLPGEICIRG 422 Query: 496 PSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 P + K Y PE TA + G+ TGD VD+D I+ R Sbjct: 423 PQIMKGYLNDPEATAATIDVEGWLHTGDIGYVDDDDEVFIVDR 465
>LGRA_BREPA (Q70LM7) Linear gramicidin synthetase subunit A [Includes:| ATP-dependent valine/leucine adenylase (Val/LeuA) (Valine/leucine activase); ATP-dependent glycine adenylase (GlyA) (Glycine activase)] Length = 2273 Score = 55.5 bits (132), Expect = 1e-07 Identities = 50/145 (34%), Positives = 66/145 (45%), Gaps = 11/145 (7%) Frame = +1 Query: 238 AKQLRLMMCGSSALPSPLMKRWEEVTCHRLLER-YGMTEFVMALSN-PLHGARKEGTV-- 405 A +LR ++ A+P L+ + EV LE YG TE + S L +E V Sbjct: 1475 ANRLRYILACGEAMPDELVPKVYEVLPEVKLENIYGPTEATIYASRYSLAKGSQESPVPI 1534 Query: 406 GKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESF----IDGG--F 564 GKPLP II G GV GELCI SL + Y P +T E F ++ G Sbjct: 1535 GKPLPNYRMYIINRHGQLQPIGVPGELCIAGASLARGYLNNPALTEEKFTPHPLEKGERI 1594 Query: 565 FKTGDTVTVDEDGYFIILGRTNADI 639 ++TGD EDG LGR + + Sbjct: 1595 YRTGDLARYREDGNIEYLGRMDHQV 1619 Score = 42.7 bits (99), Expect = 0.001 Identities = 37/119 (31%), Positives = 52/119 (43%), Gaps = 7/119 (5%) Frame = +1 Query: 289 LMKRWEEVTCHRLLERYGMTEF-VMALSNPLHGARKEGTVGKPLPRVEAKIIMDDGTETK 465 ++K+ E ++L YG TE +M + +GKP+ R I+ + Sbjct: 464 VLKKIERNGTYKLYNGYGPTECTIMVTMFEVDKPYANIPIGKPIDRTRILILDEALALQP 523 Query: 466 DGV-GELCIKSPSLFKEYWKRPEVTAESFI-----DGGFFKTGDTVTVDEDGYFIILGR 624 GV GEL I L + Y RPE+TAE FI ++TGD DG LGR Sbjct: 524 IGVAGELFIVGEGLGRGYLNRPELTAEKFIVHPQTGERMYRTGDRARFLPDGNIEFLGR 582
>CAIC_SHIFL (Q83MG9) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 522 Score = 55.5 bits (132), Expect = 1e-07 Identities = 37/106 (34%), Positives = 57/106 (53%), Gaps = 5/106 (4%) Frame = +1 Query: 322 RLLERYGMTEFVMAL-SNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDG-VGELCIKS 495 RLL YGMTE ++ + + R+ ++G+ EA+I D G +GE+CIK Sbjct: 319 RLLTSYGMTETIVGIIGDRPSDKRRWPSIGRAGFCYEAEIRDDHNRPLPAGEIGEICIKG 378 Query: 496 ---PSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 ++FKEY+ P+ TA+ G+ TGDT DE+G+F + R Sbjct: 379 VPGKTIFKEYFLNPKATAKVLEADGWLHTGDTGYRDEEGFFYFVDR 424
>LCF1_SCHPO (O60135) Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 1) (Fatty acid activator 1) Length = 676 Score = 55.5 bits (132), Expect = 1e-07 Identities = 43/133 (32%), Positives = 66/133 (49%), Gaps = 6/133 (4%) Frame = +1 Query: 244 QLRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEFVMA--LSNPLHGARKEGTVGKPL 417 +LR + G SAL SP KR+ + +L YG+TE A + NP + + G L Sbjct: 403 RLRYTLSGGSAL-SPDTKRFLSIVLCPMLIGYGLTEISAAAMVQNPAC-FNLDDSAGSLL 460 Query: 418 PRVEAKII-MDDGTETKDGV---GELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTV 585 P E K++ ++G G GE+ ++ PSL + Y R + ESF G+F+TGD Sbjct: 461 PCTEMKLVDCEEGNYNSHGHPPRGEIWLRGPSLTRGYLNRDKENKESFTPDGWFRTGDVG 520 Query: 586 TVDEDGYFIILGR 624 + +G I+ R Sbjct: 521 ELTPEGLLRIIDR 533
>ENTE_ECOLI (P10378) Enterobactin synthetase component E (Enterochelin synthase| E) [Includes: 2,3-dihydroxybenzoate-AMP ligase (EC 2.7.7.58) (Dihydroxybenzoic acid-activating enzyme); S-dihydroxybenzoyltransferase (EC 2.3.1.-)] Length = 536 Score = 55.5 bits (132), Expect = 1e-07 Identities = 41/135 (30%), Positives = 67/135 (49%), Gaps = 4/135 (2%) Frame = +1 Query: 247 LRLMMCGSSALPSPLMKRWE-EVTCHRLLERYGMTEFVMALSNPLHGARKE-GTVGKPL- 417 L+L+ G + L + L R E+ C +L + +GM E ++ + A K T G P+ Sbjct: 302 LKLLQVGGARLSATLAARIPAEIGC-QLQQVFGMAEGLVNYTRLDDSAEKIIHTQGYPMC 360 Query: 418 PRVEAKIIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVD 594 P E + +G G VG L + P F+ Y+K P+ A +F GF+ +GD +++D Sbjct: 361 PDDEVWVADAEGNPLPQGEVGRLMTRGPYTFRGYYKSPQHNASAFDANGFYCSGDLISID 420 Query: 595 EDGYFIILGRTNADI 639 +GY + GR I Sbjct: 421 PEGYITVQGREKDQI 435
>ENTE_ECO57 (Q8XBV3) Enterobactin synthetase component E (Enterochelin synthase| E) [Includes: 2,3-dihydroxybenzoate-AMP ligase (EC 2.7.7.58) (Dihydroxybenzoic acid-activating enzyme); S-dihydroxybenzoyltransferase (EC 2.3.1.-)] Length = 536 Score = 55.5 bits (132), Expect = 1e-07 Identities = 41/135 (30%), Positives = 67/135 (49%), Gaps = 4/135 (2%) Frame = +1 Query: 247 LRLMMCGSSALPSPLMKRWE-EVTCHRLLERYGMTEFVMALSNPLHGARKE-GTVGKPL- 417 L+L+ G + L + L R E+ C +L + +GM E ++ + A K T G P+ Sbjct: 302 LKLLQVGGARLSATLAARIPAEIGC-QLQQVFGMAEGLVNYTRLDDSAEKIIHTQGYPMC 360 Query: 418 PRVEAKIIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVD 594 P E + +G G VG L + P F+ Y+K P+ A +F GF+ +GD +++D Sbjct: 361 PDDEVWVADAEGNPLPQGEVGRLMTRGPYTFRGYYKSPQHNASAFDANGFYCSGDLISID 420 Query: 595 EDGYFIILGRTNADI 639 +GY + GR I Sbjct: 421 PEGYITVQGREKDQI 435
>ACSL5_HUMAN (Q9ULC5) Long-chain-fatty-acid--CoA ligase 5 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 5) (LACS 5) Length = 683 Score = 55.1 bits (131), Expect = 2e-07 Identities = 35/114 (30%), Positives = 58/114 (50%), Gaps = 2/114 (1%) Frame = +1 Query: 244 QLRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEFVMALSNPLHGARKEGTVGKPLP- 420 ++R+++ G++ + + +M + ++ E YG TE + L G G VG PL Sbjct: 412 RVRVIVTGAAPMSTSVMTFFRAAMGCQVYEAYGQTECTGGCTFTLPGDWTSGHVGVPLAC 471 Query: 421 -RVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGD 579 V+ + + D T + GE+CIK ++FK Y K PE T E+ G+ TGD Sbjct: 472 NYVKLEDVADMNYFTVNNEGEVCIKGTNVFKGYLKDPEKTQEALDSDGWLHTGD 525
>4CL_PINTA (P41636) 4-coumarate--CoA ligase (EC 6.2.1.12) (4CL)| (4-coumaroyl-CoA synthase) Length = 537 Score = 55.1 bits (131), Expect = 2e-07 Identities = 42/143 (29%), Positives = 67/143 (46%), Gaps = 12/143 (8%) Frame = +1 Query: 232 YAAKQLRLMMCGSSALPSPLMKRWEEVTCHRLLER-----YGMTEFVMALSNPLHGAR-- 390 Y +R++M G++ PL K E+ R + YGMTE L+ L A+ Sbjct: 297 YDVSSVRIIMSGAA----PLGKELEDALRERFPKAIFGQGYGMTEAGPVLAMNLAFAKNP 352 Query: 391 ---KEGTVGKPLPRVEAKIIMDDGTET--KDGVGELCIKSPSLFKEYWKRPEVTAESFID 555 K G+ G + + KI+ + E+ + GE+CI+ P + K Y PE TA + + Sbjct: 353 FPVKSGSCGTVVRNAQIKILDTETGESLPHNQAGEICIRGPEIMKGYINDPESTAATIDE 412 Query: 556 GGFFKTGDTVTVDEDGYFIILGR 624 G+ TGD +D+D I+ R Sbjct: 413 EGWLHTGDVEYIDDDEEIFIVDR 435
>LCFH_HAEIN (P44446) Putative long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase) (LACS) Length = 607 Score = 55.1 bits (131), Expect = 2e-07 Identities = 36/127 (28%), Positives = 61/127 (48%) Frame = +1 Query: 244 QLRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEFVMALSNPLHGARKEGTVGKPLPR 423 ++++M CG + L + + + + L YGMTE +S ++G +P+ Sbjct: 350 RIKMMPCGGAKLEPAIGLFFHAIGINIKLG-YGMTETTATVSCWHDFQFNPNSIGTLMPK 408 Query: 424 VEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDG 603 E KI ++ E+ ++ + K Y+K+PE TA++F + GF KTGD DE G Sbjct: 409 AEVKIGENN---------EILVRGGMVMKGYYKKPEETAQAFTEDGFLKTGDAGEFDEQG 459 Query: 604 YFIILGR 624 I R Sbjct: 460 NLFITDR 466
>MENE_BACAN (Q81K97) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 481 Score = 55.1 bits (131), Expect = 2e-07 Identities = 39/128 (30%), Positives = 63/128 (49%), Gaps = 3/128 (2%) Frame = +1 Query: 250 RLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEF---VMALSNPLHGARKEGTVGKPLP 420 R M+ G P PL++ + + + YGMTE + LS + K G+ GKPL Sbjct: 255 RCMLLGGGPAPKPLLETCVDKGIP-VYQTYGMTETSSQICTLSAD-YMLTKVGSAGKPLF 312 Query: 421 RVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDED 600 + + +I D GE+ +K P++ Y+ R + T E+ I G+ TGD +DE+ Sbjct: 313 QCQLRIEKDGVVVPPFAEGEIVVKGPNVTGGYFNREDATRET-IQNGWLHTGDLGYLDEE 371 Query: 601 GYFIILGR 624 G+ +L R Sbjct: 372 GFLYVLDR 379
>ACSL1_HUMAN (P33121) Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 1) (LACS 1) (Palmitoyl-CoA ligase 1) (Long-chain fatty acid CoA ligase 2) (Long-chain acyl-CoA synthetase 2) (LACS 2) (Acyl-CoA synthetase 1) (ACS1) (Pa Length = 698 Score = 54.7 bits (130), Expect = 2e-07 Identities = 33/114 (28%), Positives = 56/114 (49%), Gaps = 2/114 (1%) Frame = +1 Query: 244 QLRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEFVMALSNPLHGARKEGTVGKPLPR 423 ++RLM+ G++ + + ++ + E YG TE + G G VG P+P Sbjct: 427 RVRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPC 486 Query: 424 VEAKIIMDDGTE--TKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGD 579 K++ + +G GE+C+K P++F+ Y K P TAE+ G+ TGD Sbjct: 487 NLIKLVDVEEMNYMAAEGEGEVCVKGPNVFQGYLKDPAKTAEALDKDGWLHTGD 540
>CAIC_ECOLI (P31552) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 522 Score = 54.7 bits (130), Expect = 2e-07 Identities = 37/106 (34%), Positives = 56/106 (52%), Gaps = 5/106 (4%) Frame = +1 Query: 322 RLLERYGMTEFVMALSNPLHG-ARKEGTVGKPLPRVEAKIIMDDGTETKDG-VGELCIKS 495 RLL YGMTE ++ + G R+ ++G+ EA+I D G +GE+CIK Sbjct: 319 RLLTSYGMTETIVGIIGDRPGDKRRWPSIGRVGFCYEAEIRDDHNRPLPAGEIGEICIKG 378 Query: 496 ---PSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 ++FKEY+ P+ TA+ G+ TGDT DE+ +F + R Sbjct: 379 IPGKTIFKEYFLNPQATAKVLEADGWLHTGDTGYRDEEDFFYFVDR 424
>4CL1_ARATH (Q42524) 4-coumarate--CoA ligase 1 (EC 6.2.1.12) (4CL 1) (At4CL1)| (4-coumaroyl-CoA synthase 1) Length = 561 Score = 54.7 bits (130), Expect = 2e-07 Identities = 54/222 (24%), Positives = 95/222 (42%), Gaps = 14/222 (6%) Frame = +1 Query: 1 VHGLFNALFAPLYSGSVVEFMPKFSVRGVWQ--RWCESYPKGTSKNDEAITVFTGVPTVY 174 ++ L + + L G+ + MPKF + + + + C+ +TV VP + Sbjct: 259 IYALNSIMLCGLRVGAAILIMPKFEINLLLELIQRCK------------VTVAPMVPPIV 306 Query: 175 TRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCHR-----LLERY 339 + + ++ D S +R++ G++ PL K E+ + L + Y Sbjct: 307 LAIAKSSETEKYDLSS--------IRVVKSGAA----PLGKELEDAVNAKFPNAKLGQGY 354 Query: 340 GMTEFVMALSNPLHGAR-----KEGTVGKPLPRVEAKIIMDDGTET--KDGVGELCIKSP 498 GMTE L+ L A+ K G G + E KI+ D ++ ++ GE+CI+ Sbjct: 355 GMTEAGPVLAMSLGFAKEPFPVKSGACGTVVRNAEMKIVDPDTGDSLSRNQPGEICIRGH 414 Query: 499 SLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 + K Y P TAE+ G+ TGD +D+D I+ R Sbjct: 415 QIMKGYLNNPAATAETIDKDGWLHTGDIGLIDDDDELFIVDR 456
>MENE_LISMF (Q71YZ5) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 467 Score = 54.7 bits (130), Expect = 2e-07 Identities = 36/102 (35%), Positives = 51/102 (50%), Gaps = 2/102 (1%) Frame = +1 Query: 325 LLERYGMTEFVMALSN--PLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSP 498 L++ +GMTE + P K G+ GK L E KI D GE+ +K P Sbjct: 275 LVQSFGMTETASQIVTLPPKDALNKIGSSGKALFPAEVKIADD---------GEILLKGP 325 Query: 499 SLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 S+ Y + T SF+D G+FKTGD +DE+G+ +L R Sbjct: 326 SITPGYLHNKKATEASFVD-GWFKTGDIGYLDEEGFLFVLER 366
>ACSA_HELPY (O25686) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 662 Score = 54.3 bits (129), Expect = 3e-07 Identities = 58/222 (26%), Positives = 103/222 (46%), Gaps = 19/222 (8%) Frame = +1 Query: 22 LFAPLYSGS---VVEFMPKFSVRGVWQRWCESYPKGTSKNDEAITVFTGVPTVYTRLLQG 192 ++ PL G+ ++E + G W R E Y + F PT R+L Sbjct: 323 VYGPLACGATTLILEGTMSYPDYGRWWRMIEEY---------RVDKFYTSPTAI-RMLHA 372 Query: 193 YDSMNPDQQSACSYAAKQLRLMMCGSSALP-SPLMKRW--EEVTCHR--LLERYGMTEFV 357 P + Y + L+++ G+ P +P +W E++ + +++ + TE Sbjct: 373 KGENEPSK-----YNLESLKVL--GTVGEPINPTAWKWFYEKIGNSKCSIVDTWWQTETG 425 Query: 358 MALSNPLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSP--SLFKEYWK 522 + +PL GA + PLP + A+++ +DGT+TK G G LCI P S+ + W Sbjct: 426 GHIISPLPGATPIRASCATLPLPGIHAEVLNEDGTKTKPGEQGFLCITKPWPSMIRNIWG 485 Query: 523 RPEVTAESF-----IDGGF-FKTGDTVTVDEDGYFIILGRTN 630 + +S+ ++G + + +GD VDE+GY I+GRT+ Sbjct: 486 DEKRYIDSYFSQIKLNGEYVYLSGDGAIVDENGYITIIGRTD 527
>ACSA_PASMU (Q9CMW1) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 653 Score = 53.9 bits (128), Expect = 4e-07 Identities = 53/175 (30%), Positives = 83/175 (47%), Gaps = 12/175 (6%) Frame = +1 Query: 142 ITVFTGVPTVYTRLLQGYDSMNPDQQSACSYAAKQLRLM-MCGSSALPSPLMKRWEEVTC 318 I VF PT+ L + D + P++ Y LRL+ G PS M +E V Sbjct: 354 INVFYTSPTLIRSLTRLGDHI-PNK-----YDLSSLRLLGSVGEPINPSAWMWFYEVVGK 407 Query: 319 HR--LLERYGMTEFVMALSNPLHG--ARKEGTVGKPLPRVEAKIIMDDGTETK-DGVGEL 483 R +++ + TE + P+ G A K G+ PLP + A+++ ++G + + G L Sbjct: 408 SRCPIVDTWWQTETGSIMLAPIPGVTATKPGSCTLPLPGIMAEVLDENGQKCAVEQGGAL 467 Query: 484 CIKSP--SLFKEYWKRPEVTAESFID----GGFFKTGDTVTVDEDGYFIILGRTN 630 IK P S+ + W PE ++ G ++ GD D+DGYF ILGRT+ Sbjct: 468 AIKRPFPSMLRTIWNDPERYKSTYFPAEYGGKYYIAGDNAHRDKDGYFWILGRTD 522
>FAT2_YEAST (P38137) Peroxisomal-coenzyme A synthetase (EC 6.-.-.-)| Length = 543 Score = 53.9 bits (128), Expect = 4e-07 Identities = 41/131 (31%), Positives = 63/131 (48%), Gaps = 5/131 (3%) Frame = +1 Query: 247 LRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTE--FVMALSNPLHGARKEGTVGKPLP 420 +R + SSAL + E+ +LE Y MTE M +N G RK GTVG+ P Sbjct: 304 IRFIRSCSSALAPATFHKLEKEFNAPVLEAYAMTEASHQMTSNNLPPGKRKPGTVGQ--P 361 Query: 421 RVEAKIIMDDGTET--KDGVGELCIKSPSLFKEYWKRPEVTAESFID-GGFFKTGDTVTV 591 + +I+DD VGE+ I+ ++ Y P+ E+F +F+TGD Sbjct: 362 QGVTVVILDDNDNVLPPGKVGEVSIRGENVTLGYANNPKANKENFTKRENYFRTGDQGYF 421 Query: 592 DEDGYFIILGR 624 D +G+ ++ GR Sbjct: 422 DPEGFLVLTGR 432
>ACSL1_MOUSE (P41216) Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 1) (LACS 1) Length = 699 Score = 53.5 bits (127), Expect = 5e-07 Identities = 34/114 (29%), Positives = 54/114 (47%), Gaps = 2/114 (1%) Frame = +1 Query: 244 QLRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEFVMALSNPLHGARKEGTVGKPLPR 423 ++RLM+ G++ + + ++ + E YG TE L G G VG P+P Sbjct: 428 KVRLMITGAAPVSATVLTFLRTALGCQFYEGYGQTECTAGCCLSLPGDWTAGHVGAPMPC 487 Query: 424 VEAKIIMDDGTE--TKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGD 579 K++ + G GE+C+K ++FK Y K P TAE+ G+ TGD Sbjct: 488 NYVKLVDVEEMNYLASKGEGEVCVKGANVFKGYLKDPARTAEALDKDGWLHTGD 541
>ACSL5_RAT (O88813) Long-chain-fatty-acid--CoA ligase 5 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 5) (LACS 5) Length = 683 Score = 53.5 bits (127), Expect = 5e-07 Identities = 35/114 (30%), Positives = 56/114 (49%), Gaps = 2/114 (1%) Frame = +1 Query: 244 QLRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEFVMALSNPLHGARKEGTVGKPLPR 423 ++RLM+ G++ + +P++ + + E YG TE S G G VG P+ Sbjct: 412 KVRLMITGAAPISTPVLTFFRAAMGCWVFEAYGQTECTAGCSITSPGDWTAGHVGTPVSC 471 Query: 424 --VEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGD 579 V+ + + D + + GE+CIK ++FK Y K PE T E G+ TGD Sbjct: 472 NFVKLEDVADMNYFSVNNEGEICIKGNNVFKGYLKDPEKTQEVLDKDGWLHTGD 525
>MENE_LISMO (P58730) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 467 Score = 53.5 bits (127), Expect = 5e-07 Identities = 35/102 (34%), Positives = 51/102 (50%), Gaps = 2/102 (1%) Frame = +1 Query: 325 LLERYGMTEFVMALSN--PLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSP 498 L++ +GMTE + P K G+ GK L E KI D GE+ +K P Sbjct: 275 LVQSFGMTETASQIVTLPPKDALNKIGSSGKALFPAEVKIADD---------GEILLKGP 325 Query: 499 SLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 S+ Y + T SF+D G+FKTGD +DE+G+ ++ R Sbjct: 326 SITPGYLHNKKATEASFVD-GWFKTGDIGYLDEEGFLFVVER 366
>PPS2_BACSU (P39846) Peptide synthetase 2| Length = 2560 Score = 53.5 bits (127), Expect = 5e-07 Identities = 57/217 (26%), Positives = 92/217 (42%), Gaps = 11/217 (5%) Frame = +1 Query: 7 GLFNALFAPLYSGSVVEFMPKFSVRGVW--QRWCESYPKGTSKNDEAITVFTGVPTVYTR 180 G +LF PL SG+ V + V +R Y ++ VP++Y Sbjct: 661 GCVTSLFTPLLSGACVLLTTDDEAKDVLALKRKIARYK---------VSHMIIVPSLYRV 711 Query: 181 LLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCH--RLLERYGMTEF 354 LL+ M D AK LR++ A+ L++ ++ C L YG TE Sbjct: 712 LLE---VMTADD-------AKSLRIVTFAGEAVTPDLLEL-NQIICPSAELANEYGPTEN 760 Query: 355 VMALSNPLHGARKEG-TVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPE 531 +A + H +KE T+G P+ + ++ + + GELCI L + Y+K+ E Sbjct: 761 SVATTILRHLNKKERITIGHPIRNTKVFVLHGNQMQPIGAAGELCISGAGLARGYYKQQE 820 Query: 532 VTAESFIDGGF------FKTGDTVTVDEDGYFIILGR 624 +T ++F D F ++TGD DG +GR Sbjct: 821 LTQKAFSDHPFLEGERLYRTGDAGRFLPDGTIEYIGR 857
>ALKK_PSEOL (Q00594) Medium-chain-fatty-acid--CoA ligase (EC 6.2.1.-)| (Medium-chain acyl-CoA synthetase) Length = 546 Score = 53.5 bits (127), Expect = 5e-07 Identities = 49/179 (27%), Positives = 79/179 (44%), Gaps = 16/179 (8%) Frame = +1 Query: 136 EAITVFTGVPTVYTRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVT 315 E +++ GVP V+ LL QS L ++ G SA P+ +++ + ++ Sbjct: 267 EGVSIALGVPVVWQGLLAAQAGNGSKSQS--------LTRVVVGGSACPASMIREFNDIY 318 Query: 316 CHRLLERYGMTE---FVMALSNPLH----------GARKEGTVGKPLPRVEAKIIMDDGT 456 ++ +GMTE F A + H RK + G+P VE KI+ D+G Sbjct: 319 GVEVIHAWGMTELSPFGTANTPLAHHVDLSPDEKLSLRK--SQGRPPYGVELKIVNDEGI 376 Query: 457 ET-KDG--VGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 +DG G L + + K+Y+ S + G+F TGD T+D DG+ I R Sbjct: 377 RLPEDGRSKGNLMARGHWVIKDYFHSDP---GSTLSDGWFSTGDVATIDSDGFMTICDR 432
>4CL2_SOLTU (P31685) 4-coumarate--CoA ligase 2 (EC 6.2.1.12) (4CL 2)| (4-coumaroyl-CoA synthase 2) Length = 545 Score = 53.5 bits (127), Expect = 5e-07 Identities = 57/220 (25%), Positives = 92/220 (41%), Gaps = 12/220 (5%) Frame = +1 Query: 1 VHGLFNALFAPLYSGSVVEFMPKFSVRGVWQRWCESYPKGTSKNDEAITVFTGVPTVYTR 180 ++ L + L L G+ + M KF + ++ E PK +T+ VP + Sbjct: 241 IYSLNSVLLCALRVGAAILIMQKFDIA----QFLELIPK------HKVTIGPFVPPIVLA 290 Query: 181 LLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCHR-----LLERYGM 345 + + N D S +R +M G++ PL K E+ + L + YGM Sbjct: 291 IAKSPLVHNYDLSS--------VRTVMSGAA----PLGKELEDAVRAKFPNAKLGQGYGM 338 Query: 346 TEFVMALSNPLHGAR-----KEGTVGKPLPRVEAKIIMDDG--TETKDGVGELCIKSPSL 504 TE L+ L A+ K G G + E KI+ D + ++ GE+CI+ + Sbjct: 339 TEAGPVLAMCLAFAKEPFDIKSGACGTVVRNAEMKIVDPDTGCSLPRNQPGEICIRGDQI 398 Query: 505 FKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 K Y PE TA + G+ TGD +D+D I+ R Sbjct: 399 MKGYLNDPEATARTIEKEGWLHTGDIGFIDDDDELFIVDR 438
>4CL1_SOLTU (P31684) 4-coumarate--CoA ligase 1 (EC 6.2.1.12) (4CL 1)| (4-coumaroyl-CoA synthase 1) Length = 545 Score = 53.1 bits (126), Expect = 7e-07 Identities = 57/220 (25%), Positives = 92/220 (41%), Gaps = 12/220 (5%) Frame = +1 Query: 1 VHGLFNALFAPLYSGSVVEFMPKFSVRGVWQRWCESYPKGTSKNDEAITVFTGVPTVYTR 180 ++ L + L L G+ + M KF + ++ E PK +T+ VP + Sbjct: 241 IYSLNSVLLCALRVGAAILIMQKFDIA----QFLELIPK------HKVTIGPFVPPIVLA 290 Query: 181 LLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCHR-----LLERYGM 345 + + N D S +R +M G++ PL K E+ + L + YGM Sbjct: 291 IAKSPLVDNYDLSS--------VRTVMSGAA----PLGKELEDAVRAKFPNAKLGQGYGM 338 Query: 346 TEFVMALSNPLHGAR-----KEGTVGKPLPRVEAKIIMDDG--TETKDGVGELCIKSPSL 504 TE L+ L A+ K G G + E KI+ D + ++ GE+CI+ + Sbjct: 339 TEAGPVLAMCLAFAKEPFDIKSGACGTVVRNAEMKIVDPDTGCSLPRNQPGEICIRGDQI 398 Query: 505 FKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 K Y PE TA + G+ TGD +D+D I+ R Sbjct: 399 MKGYLNDPEATARTIEKEGWLHTGDIGFIDDDDELFIVDR 438
>ACSL5_MOUSE (Q8JZR0) Long-chain-fatty-acid--CoA ligase 5 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 5) (LACS 5) Length = 683 Score = 52.8 bits (125), Expect = 9e-07 Identities = 35/114 (30%), Positives = 56/114 (49%), Gaps = 2/114 (1%) Frame = +1 Query: 244 QLRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEFVMALSNPLHGARKEGTVGKPLPR 423 ++RLM+ G++ + +P++ + + E YG TE S G G VG P+ Sbjct: 412 KVRLMITGAAPISTPVLTFFRAAMGCWVFEAYGQTECTGGCSITSPGDWTAGHVGTPVAC 471 Query: 424 --VEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGD 579 V+ + + D + + GE+CIK ++FK Y K PE T E G+ TGD Sbjct: 472 NFVKLEDVADMNYFSVNNEGEICIKGNNVFKGYLKDPEKTQEVLDKDGWLHTGD 525
>SRFAA_BACSU (P27206) Surfactin synthetase subunit 1| Length = 3588 Score = 52.8 bits (125), Expect = 9e-07 Identities = 41/141 (29%), Positives = 63/141 (44%), Gaps = 11/141 (7%) Frame = +1 Query: 250 RLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEF-VMALSNPLHGARKEGT---VGKPL 417 ++M G A + K + V +LL YG +E V A +P+ + +GKP+ Sbjct: 1763 KIMFGGERASVEHVRKALQTVGKGKLLHMYGPSESTVFATYHPVDELEEHTLSVPIGKPV 1822 Query: 418 PRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTG 576 E I+ G G+ GELC+ L K Y+ RPE+T E F+ F +KTG Sbjct: 1823 SNTEVYILDRTGHVQPAGIAGELCVTGEGLVKGYYNRPELTEEKFVPHPFTSGERMYKTG 1882 Query: 577 DTVTVDEDGYFIILGRTNADI 639 D +G +GR + + Sbjct: 1883 DLARWLPNGTIEFIGRIDHQV 1903 Score = 44.7 bits (104), Expect = 2e-04 Identities = 54/195 (27%), Positives = 80/195 (41%), Gaps = 19/195 (9%) Frame = +1 Query: 112 PKGTSKNDEAITVFTGVPTVYTRLLQGYDSMNPDQQSACSYAAKQLRLMMCG----SSAL 279 PK T N A+T + ++ G + +A + +L+ M+ G SS + Sbjct: 674 PKKTVTNGAALTAYYRKNSI--EATDGTPAHLQMLAAAGDFEGLKLKHMLIGGEGLSSVV 731 Query: 280 PSPLMKRWEEV-TCHRLLERYGMTEFVMALSNPLHGARKEGTV-------GKPLPRVEAK 435 L+K ++E T RL YG TE + S +H E V GK L Sbjct: 732 ADKLLKLFKEAGTAPRLTNVYGPTETCVDAS--VHPVIPENAVQSAYVPIGKALGNNRLY 789 Query: 436 IIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVD 594 I+ G +GV GEL I + + Y PE+T E F+ F ++TGD V Sbjct: 790 ILDQKGRLQPEGVAGELYIAGDGVGRGYLHLPELTEEKFLQDPFVPGDRMYRTGDVVRWL 849 Query: 595 EDGYFIILGRTNADI 639 DG LGR + + Sbjct: 850 PDGTIEYLGREDDQV 864
>ACSL6_RAT (P33124) Long-chain-fatty-acid--CoA ligase 6 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 6) (LACS 6) (Long-chain-fatty-acid--CoA ligase, brain isozyme) Length = 697 Score = 52.4 bits (124), Expect = 1e-06 Identities = 32/90 (35%), Positives = 44/90 (48%), Gaps = 4/90 (4%) Frame = +1 Query: 322 RLLERYGMTEFVMALSNPLHGARKEGTVGKPLPRVEAKIIMDDGTE----TKDGVGELCI 489 ++ E YG TE + G G VG PLP K++ D E T G GE+C+ Sbjct: 453 QVYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLV--DAEELNYWTSKGEGEICV 510 Query: 490 KSPSLFKEYWKRPEVTAESFIDGGFFKTGD 579 K P++FK Y K + T E+ G+ TGD Sbjct: 511 KGPNVFKGYLKDEDRTKEALDSDGWLHTGD 540
>DHBF_BACSU (P45745) Dimodular nonribosomal peptide synthetase| Length = 2378 Score = 52.4 bits (124), Expect = 1e-06 Identities = 54/217 (24%), Positives = 97/217 (44%), Gaps = 11/217 (5%) Frame = +1 Query: 22 LFAPLYSGSVVEFMPKFSVRGVWQRWCESYPKGTSKNDEAITVFTGVPTVYTRLLQGYDS 201 L+ PL SG+ + K ++R E + I + PT++ L+ + Sbjct: 663 LYLPLISGAQIVIAKKETIR-------EPQALAQMIENFDINIMQATPTLWHALV----T 711 Query: 202 MNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEFVM--ALSNP 375 P++ + LR+++ G ALPS L++ +++ C + YG TE + A + Sbjct: 712 SEPEK-------LRGLRVLV-GGEALPSGLLQELQDLHCS-VTNLYGPTETTIWSAAAFL 762 Query: 376 LHGARKEGTVGKPLPRVEAKIIMDDGTETKDG--VGELCIKSPSLFKEYWKRPEVTAESF 549 G + +GKP+ + ++D+G + VGEL I L + Y+ RP++TAE F Sbjct: 763 EEGLKGVPPIGKPIWNTQV-YVLDNGLQPVPPGVVGELYIAGTGLARGYFHRPDLTAERF 821 Query: 550 IDGGF-------FKTGDTVTVDEDGYFIILGRTNADI 639 + + ++TGD DG +GR + I Sbjct: 822 VADPYGPPGTRMYRTGDQARWRADGSLDYIGRADHQI 858
>MENE_ENTFA (Q838K1) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 485 Score = 52.4 bits (124), Expect = 1e-06 Identities = 47/164 (28%), Positives = 78/164 (47%), Gaps = 4/164 (2%) Frame = +1 Query: 145 TVFTGVPTVYTRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCHR 324 TV + V T+ +LL Y Y+A +++ G P L + E+ Sbjct: 229 TVISVVATMLQQLLSVYPE--------AGYSASFKGMLLGGGPIAPDKLAQCEEKGI--P 278 Query: 325 LLERYGMTEF---VMALSNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDG-VGELCIK 492 +++ YGMTE V+AL A K G+ G+PL ++ KI+ + G E + VGE+ +K Sbjct: 279 VIQSYGMTETCSQVVALKFE-DAALKIGSAGQPLKDMQIKIVDELGQEQPEKQVGEILLK 337 Query: 493 SPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 P++ Y + + E + G+FKTGD +D Y ++ R Sbjct: 338 GPNVVSGYLNQRQ--PEKWTADGWFKTGDMGYLDAQSYLYLVSR 379
>LGRC_BREPA (Q70LM5) Linear gramicidin synthetase subunit C [Includes:| ATP-dependent valine adenylase (ValA) (Valine activase); ATP-dependent D-valine adenylase (D-ValA) (D-valine activase); Valine racemase [ATP-hydrolyzing] (EC 5.1.1.-); ATP-dependent tr Length = 7756 Score = 52.0 bits (123), Expect = 2e-06 Identities = 35/118 (29%), Positives = 58/118 (49%), Gaps = 13/118 (11%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPL----HGARKEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCI 489 L+ +YG TE + + + G ++G+P+ V+ I+ + GV GEL I Sbjct: 6977 LVNQYGPTENAVVATAGIVAVQAGQVTPPSIGRPIDNVQVYILDEQRQPVPIGVTGELYI 7036 Query: 490 KSPSLFKEYWKRPEVTAESFIDGGF--------FKTGDTVTVDEDGYFIILGRTNADI 639 SL + Y+KRP++T E F+D F ++TGD V DG +GR++ + Sbjct: 7037 AGSSLARGYYKRPDLTQERFVDNPFTANRGAKMYRTGDLVRYLPDGQIEFIGRSDDQV 7094 Score = 52.0 bits (123), Expect = 2e-06 Identities = 42/140 (30%), Positives = 62/140 (44%), Gaps = 9/140 (6%) Frame = +1 Query: 247 LRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEFVMALSNPLHGA-RKEGTVGKPLPR 423 L+ ++ G A L+ R+ + + YG TE + + L A K +G+PL Sbjct: 3317 LQTLIVGGEAPSRELVARYADR--RQFFNCYGPTEATVCSTMMLCNAGMKSAPIGRPLAN 3374 Query: 424 VEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF-------FKTGD 579 ++ + GV GEL I L + YW RPE+TAE FI F ++TGD Sbjct: 3375 ATLYVLDANQKPVPVGVPGELYIGGKGLARGYWNRPELTAERFIAHPFGAKGERLYRTGD 3434 Query: 580 TVTVDEDGYFIILGRTNADI 639 V DG LGR + + Sbjct: 3435 LVRYLPDGNLEFLGRIDTQV 3454 Score = 50.4 bits (119), Expect = 4e-06 Identities = 42/140 (30%), Positives = 61/140 (43%), Gaps = 9/140 (6%) Frame = +1 Query: 247 LRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEF-VMALSNPLHGARKEGTVGKPLPR 423 LR ++ G A L+ R+ T + + YG TE V A K +G+P+ Sbjct: 5896 LRTIIVGGEAPSRELVARY--ATGRQFINCYGPTETTVTATLKHCQDDGKNPPIGRPIAN 5953 Query: 424 VEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFI-------DGGFFKTGD 579 ++ GV GEL I + + YW RPE+TAE FI D ++TGD Sbjct: 5954 TTVYVLDAHLQPVPIGVPGELYIGGKGVARGYWNRPELTAERFIADPFGQADERLYRTGD 6013 Query: 580 TVTVDEDGYFIILGRTNADI 639 V E+G LGR + + Sbjct: 6014 LVRYLENGELEFLGRIDDQV 6033 Score = 42.7 bits (99), Expect = 0.001 Identities = 33/118 (27%), Positives = 53/118 (44%), Gaps = 13/118 (11%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPL----HGARKEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCI 489 L +YG TE + + + G ++G+P+ V+ ++ + GV GEL I Sbjct: 4393 LANQYGPTENAVVATAGIVPAAAGQVSAPSIGRPIDNVQVYVLDEKLQPVPIGVAGELYI 4452 Query: 490 KSPSLFKEYWKRPEVTAESFIDGGF--------FKTGDTVTVDEDGYFIILGRTNADI 639 SL + Y RP++T E FI + +KTGD V DG +GR + + Sbjct: 4453 AGDSLARGYLHRPDLTRERFIANPYGQKAGARMYKTGDLVRYLPDGNIEFIGRADDQV 4510 Score = 41.6 bits (96), Expect = 0.002 Identities = 36/144 (25%), Positives = 61/144 (42%), Gaps = 13/144 (9%) Frame = +1 Query: 247 LRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTE-FVMALSNPLHGARKEGT---VGKP 414 +R ++ G + P +++ + ++ YG TE P+ +E T +G+P Sbjct: 1791 VRQLLVGGDVVSVPHVRKVLALDGVTVINGYGPTENTTFTCCYPVTELAEEITSFPIGRP 1850 Query: 415 LPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF--------F 567 + ++ + GV GEL I L Y PE+TAE F+D F + Sbjct: 1851 ISNTTVYVLDKNRQPVPLGVAGELYIGGDGLASGYLNNPELTAERFVDNPFDPQKASRLY 1910 Query: 568 KTGDTVTVDEDGYFIILGRTNADI 639 +TGD V DG +GR + + Sbjct: 1911 RTGDLVRYLPDGAIEFIGRIDNQV 1934 Score = 30.8 bits (68), Expect = 3.6 Identities = 31/144 (21%), Positives = 58/144 (40%), Gaps = 13/144 (9%) Frame = +1 Query: 247 LRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTE-FVMALSNPLHGARKEGT---VGKP 414 +R ++ G + P +++ + ++ YG TE P+ ++ T +G+P Sbjct: 726 VRQLLVGGDVVSVPHVRKVLALGGVTVINGYGPTENTTFTCCYPVTELSEDITSFPIGRP 785 Query: 415 LPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF--------F 567 + ++ G GEL I L Y E+TAE F++ F + Sbjct: 786 ISNTTVYVLDKHKQPVPYGAAGELYIGGDGLALGYLNNAELTAERFVENPFDPQKGSRLY 845 Query: 568 KTGDTVTVDEDGYFIILGRTNADI 639 +TGD V +G +GR + + Sbjct: 846 RTGDLVRYLPNGTIEFIGRIDNQV 869
>ACSL6_MOUSE (Q91WC3) Long-chain-fatty-acid--CoA ligase 6 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 6) (LACS 6) Length = 697 Score = 51.2 bits (121), Expect = 3e-06 Identities = 32/90 (35%), Positives = 44/90 (48%), Gaps = 4/90 (4%) Frame = +1 Query: 322 RLLERYGMTEFVMALSNPLHGARKEGTVGKPLPRVEAKIIMDDGTE----TKDGVGELCI 489 ++ E YG TE + G G VG PLP K++ D E T G GE+C+ Sbjct: 453 QVYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLV--DAEELNYWTCKGEGEICV 510 Query: 490 KSPSLFKEYWKRPEVTAESFIDGGFFKTGD 579 K P++FK Y K + T E+ G+ TGD Sbjct: 511 KGPNVFKGYLKDEDRTKEALDSDGWLHTGD 540
>MENE_STAEQ (Q5HNB2) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 474 Score = 51.2 bits (121), Expect = 3e-06 Identities = 41/130 (31%), Positives = 63/130 (48%), Gaps = 4/130 (3%) Frame = +1 Query: 247 LRLMMCGSSALPSPLMKRWEEVTCHRL--LERYGMTEFVMAL--SNPLHGARKEGTVGKP 414 L ++ G + L L+ E+ +RL +GMTE ++P + TVGKP Sbjct: 245 LEKILLGGAKLSPQLI---EQALTYRLPVYNSFGMTETCSQFLTASPQMLKERFDTVGKP 301 Query: 415 LPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVD 594 VE KI + G GEL IK ++ Y P+ ++F + G+F+TGD +D Sbjct: 302 SENVEVKIKNPNAY----GHGELLIKGENVMNGYLY-PKYLKDTFDNDGYFQTGDIAEID 356 Query: 595 EDGYFIILGR 624 ++GY II R Sbjct: 357 DEGYVIIYDR 366
>4CL2_ARATH (Q9S725) 4-coumarate--CoA ligase 2 (EC 6.2.1.12) (4CL 2) (At4Cl2)| (4-coumaroyl-CoA synthase 2) Length = 556 Score = 51.2 bits (121), Expect = 3e-06 Identities = 52/220 (23%), Positives = 93/220 (42%), Gaps = 12/220 (5%) Frame = +1 Query: 1 VHGLFNALFAPLYSGSVVEFMPKFSVRGVWQRWCESYPKGTSKNDEAITVFTGVPTVYTR 180 ++ L + + L G+ + MPKF + + ++ +TV VP + Sbjct: 252 IYALNSIMLCSLRIGATILIMPKFEITLLLEQIQRC----------KVTVAMVVPPIVLA 301 Query: 181 LLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCHR-----LLERYGM 345 + + +P+ + Y +R++ G++ PL K E+ + L + YGM Sbjct: 302 IAK-----SPETEK---YDLSSVRMVKSGAA----PLGKELEDAISAKFPNAKLGQGYGM 349 Query: 346 TEFVMALSNPLHGAR-----KEGTVGKPLPRVEAKIIMDDGTET--KDGVGELCIKSPSL 504 TE L+ L A+ K G G + E KI+ D ++ ++ GE+CI+ + Sbjct: 350 TEAGPVLAMSLGFAKEPFPVKSGACGTVVRNAEMKILDPDTGDSLPRNKPGEICIRGNQI 409 Query: 505 FKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 K Y P TA + G+ TGD +D+D I+ R Sbjct: 410 MKGYLNDPLATASTIDKDGWLHTGDVGFIDDDDELFIVDR 449
>4CL1_TOBAC (O24145) 4-coumarate--CoA ligase 1 (EC 6.2.1.12) (4CL 1)| (4-coumaroyl-CoA synthase 1) Length = 547 Score = 51.2 bits (121), Expect = 3e-06 Identities = 43/144 (29%), Positives = 64/144 (44%), Gaps = 12/144 (8%) Frame = +1 Query: 229 SYAAKQLRLMMCGSSALPSPLMKRWEEVTCHR-----LLERYGMTEFVMALSNPLHGAR- 390 SY +R +M G++ PL K E+ + L + YGMTE L+ L A+ Sbjct: 301 SYDLSSVRTVMSGAA----PLGKELEDAVRTKFPNAKLGQGYGMTEAGPVLAMCLAFAKE 356 Query: 391 ----KEGTVGKPLPRVEAKIIMDDG--TETKDGVGELCIKSPSLFKEYWKRPEVTAESFI 552 K G G + E KI+ D + ++ GE+CI+ + K Y PE T + Sbjct: 357 PFDIKSGACGTVVRNAEMKIVDPDTGCSLPRNQPGEICIRGDQIMKGYLNDPEATTRTID 416 Query: 553 DGGFFKTGDTVTVDEDGYFIILGR 624 G+ TGD +DED I+ R Sbjct: 417 KEGWLHTGDIGFIDEDDELFIVDR 440
>ACSL6_HUMAN (Q9UKU0) Long-chain-fatty-acid--CoA ligase 6 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 6) (LACS 6) Length = 697 Score = 50.8 bits (120), Expect = 3e-06 Identities = 31/90 (34%), Positives = 44/90 (48%), Gaps = 4/90 (4%) Frame = +1 Query: 322 RLLERYGMTEFVMALSNPLHGARKEGTVGKPLPRVEAKIIMDDGTETK----DGVGELCI 489 ++ E YG TE + G G VG PLP K++ D E G GE+C+ Sbjct: 453 QVYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLV--DVEELNYWACKGEGEICV 510 Query: 490 KSPSLFKEYWKRPEVTAESFIDGGFFKTGD 579 + P++FK Y K P+ T E+ G+ TGD Sbjct: 511 RGPNVFKGYLKDPDRTKEALDSDGWLHTGD 540
>LGRD_BREPA (Q70LM4) Linear gramicidin synthetase subunit D [Includes:| ATP-dependent tryptophan adenylase (TrpA) (Tryptophan activase); ATP-dependent D-leucine adenylase (D-LeuA) (D-Leucine activase); Leucine racemase [ATP-hydrolyzing] (EC 5.1.1.-); ATP-d Length = 5085 Score = 50.8 bits (120), Expect = 3e-06 Identities = 41/135 (30%), Positives = 59/135 (43%), Gaps = 9/135 (6%) Frame = +1 Query: 247 LRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEFVMA-LSNPLHGARKEGTVGKPLPR 423 L ++ G A L+ R+ T + YG TE + + L T+G+P P Sbjct: 3301 LAVLEVGGDACSRELVARY--ATGRKFFNCYGPTEATVGTVIKQLTLDDDTPTIGRPFPN 3358 Query: 424 VEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF-------FKTGD 579 + ++ + GV GEL I L + YW RPE+TAE F+ F ++TGD Sbjct: 3359 TKLYVLDQNRKPVPVGVPGELYIGGECLARGYWNRPELTAERFVANPFGQPGERLYRTGD 3418 Query: 580 TVTVDEDGYFIILGR 624 V DG LGR Sbjct: 3419 LVRYLPDGNVDYLGR 3433 Score = 50.4 bits (119), Expect = 4e-06 Identities = 40/140 (28%), Positives = 60/140 (42%), Gaps = 9/140 (6%) Frame = +1 Query: 247 LRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEFVMALSNPL-HGARKEGTVGKPLPR 423 L ++ G A L+ R+ + YG TE + + L +G+P+ Sbjct: 717 LHTLIVGGEAPSRELVARY--APGRQFFNCYGPTEATVCSTMMLCQAGMNNPPIGRPIAN 774 Query: 424 VEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF-------FKTGD 579 ++ + GV GEL I L + YW RPE+TAESFI F ++TGD Sbjct: 775 ATVYVLDANLNPVPVGVPGELYIGGKGLARGYWNRPELTAESFIPHPFGTAGERLYRTGD 834 Query: 580 TVTVDEDGYFIILGRTNADI 639 V +DG LGR + + Sbjct: 835 LVRYRQDGNLEFLGRIDHQV 854 Score = 43.1 bits (100), Expect = 7e-04 Identities = 34/115 (29%), Positives = 52/115 (45%), Gaps = 13/115 (11%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPL----HGARKEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCI 489 L+ +YG TE + + + G T+G+P+ V+ I+ GV GEL I Sbjct: 1798 LVNQYGPTENTVVATAGIVPKEAGQTAAPTIGRPIDNVQVYILDAHRQPVPVGVSGELYI 1857 Query: 490 KSPSLFKEYWKRPEVTAESFIDGGF--------FKTGDTVTVDEDGYFIILGRTN 630 SL + Y RP++T E F+ F ++TGD V DG +GR + Sbjct: 1858 GGSSLARGYLNRPDLTQERFVAHPFTEKAGARLYRTGDLVRSLPDGSIEFIGRAD 1912 Score = 42.4 bits (98), Expect = 0.001 Identities = 31/116 (26%), Positives = 51/116 (43%), Gaps = 10/116 (8%) Frame = +1 Query: 322 RLLERYGMTEFVMALSNPL--HGARKEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIK 492 ++ YG TE + ++ + GA E +G+P ++ GV GEL + Sbjct: 4378 KVFNLYGPTEDTVYSTHAIVTKGATNEPLIGRPQFNTHVFVLDSHRKPVPVGVPGELYLS 4437 Query: 493 SPSLFKEYWKRPEVTAESFIDGGF-------FKTGDTVTVDEDGYFIILGRTNADI 639 L + Y RP++TAE F+ F ++TGD V DG +GR + + Sbjct: 4438 GSGLARGYLHRPDLTAERFVQNPFREPGARMYRTGDLVRYLPDGNLQFVGRVDYQV 4493
>ACSA_CAMJE (Q9PMD2) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 657 Score = 50.4 bits (119), Expect = 4e-06 Identities = 61/220 (27%), Positives = 95/220 (43%), Gaps = 17/220 (7%) Frame = +1 Query: 22 LFAPLYSGSVV---EFMPKFSVRGVWQRWCESYPKGTSKNDEAITVFTGVPTVYTRLLQG 192 ++ PL G+ E P + G W R E Y I+ F PT R+L Sbjct: 317 VYGPLACGATTIMHEGTPTYPNSGRWWRMIEEYQ---------ISKFYTSPTAI-RMLHA 366 Query: 193 YDSMNPDQQSACSYAAKQLRLM-MCGSSALPSPLMKRWEEV--TCHRLLERYGMTEFVMA 363 D+ N ++ Y L ++ G PS ++E+ T +++ + TE Sbjct: 367 -DAPNEPRK----YDLSTLEVLGTVGEPINPSAWKWFYDEIGGTKSPIVDTWWQTETGGH 421 Query: 364 LSNPLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSP--SLFKEYWKRP 528 + PL GA K G PLP + A++I ++G + +G G LCI P S+ + W Sbjct: 422 MITPLPGATPLKPGCATLPLPGIFAEVIDEEGNKKDEGEDGLLCITKPWPSMIRGIWGND 481 Query: 529 EVTAESFI-----DG-GFFKTGDTVTVDEDGYFIILGRTN 630 E ES+ DG + +GD D++GY I GRT+ Sbjct: 482 ERYIESYFSQAKKDGKAVYFSGDGAFYDKNGYITITGRTD 521
>ACSA_NITEU (Q82SI5) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 655 Score = 50.1 bits (118), Expect = 6e-06 Identities = 48/176 (27%), Positives = 76/176 (43%), Gaps = 13/176 (7%) Frame = +1 Query: 142 ITVFTGVPTVYTRLLQGYDSMNPDQQSACSYAAKQLRLM-MCGSSALPSPLMKRWEEVTC 318 IT F PT L++ + Y LRL+ G P M + V Sbjct: 356 ITTFYTAPTAIRSLIKLGSDL------PAKYDLSSLRLLGSVGEPINPEAWMWYYTVVGQ 409 Query: 319 HR--LLERYGMTEFVMALSNPLHGA--RKEGTVGKPLPRVEAKIIMDDGTETKDGVGE-L 483 R +++ + TE + P GA K G+ PLP ++A ++ + G + G G L Sbjct: 410 SRCPVVDTWWQTETGCHMIAPAPGAISTKPGSCTLPLPGIDAAVVDETGHPVEQGKGGFL 469 Query: 484 CIKSP--SLFKEYWKRPEVTAESFID-----GGFFKTGDTVTVDEDGYFIILGRTN 630 IK P S+ + W PE +++ G ++ GD+ D+DGYF I+GR + Sbjct: 470 VIKRPFPSMLRTLWNDPERFRKTYFPTDIAGGRYYLAGDSAHRDQDGYFWIMGRVD 525
>4CL2_SOYBN (P31687) 4-coumarate--CoA ligase 2 (EC 6.2.1.12) (4CL 2)| (4-coumaroyl-CoA synthase 2) (Clone 4CL16) Length = 562 Score = 50.1 bits (118), Expect = 6e-06 Identities = 59/221 (26%), Positives = 90/221 (40%), Gaps = 13/221 (5%) Frame = +1 Query: 1 VHGLFNALFAPLYSGSVVEFMPKFSVRGVWQRWCESYPKGTSKNDEAITVFTGVPTVYTR 180 + L + L L +GS V M KF + G + + ++V VP + Sbjct: 256 IFSLNSVLLCALRAGSAVLLMQKFEI-GTLLELIQRH---------RVSVAMVVPPLVLA 305 Query: 181 LLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCHRLLER-----YGM 345 L + NP + +RL++ G++ PL K EE +R+ + YGM Sbjct: 306 LAK-----NP---MVADFDLSSIRLVLSGAA----PLGKELEEALRNRMPQAVLGQGYGM 353 Query: 346 TEFVMALSNPLHGAR-----KEGTVGKPLPRVEAKIIMDDGTETKDGV---GELCIKSPS 501 TE LS L A+ K G+ G + E K++ D T G GE+CI+ Sbjct: 354 TEAGPVLSMCLGFAKQPFQTKSGSCGTVVRNAELKVV-DPETGRSLGYNQPGEICIRGQQ 412 Query: 502 LFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 + K Y TA + G+ TGD VD+D I+ R Sbjct: 413 IMKGYLNDEAATASTIDSEGWLHTGDVGYVDDDDEIFIVDR 453
>MENE_STAAW (Q8NVZ4) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 492 Score = 50.1 bits (118), Expect = 6e-06 Identities = 34/100 (34%), Positives = 48/100 (48%), Gaps = 4/100 (4%) Frame = +1 Query: 337 YGMTE----FVMALSNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSL 504 +GMTE F+ A LH + TVG P V+ KI K+G GEL IK ++ Sbjct: 303 FGMTETCSQFLTATPEMLHA--RPDTVGMPSANVDVKI----KNPNKEGHGELMIKGANV 356 Query: 505 FKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 Y ++T + G+F TGD +D +GY +I R Sbjct: 357 MNGYLYPTDLTGT--FENGYFNTGDIAEIDHEGYVMIYDR 394
>MENE_STAAU (Q53634) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 492 Score = 50.1 bits (118), Expect = 6e-06 Identities = 34/100 (34%), Positives = 48/100 (48%), Gaps = 4/100 (4%) Frame = +1 Query: 337 YGMTE----FVMALSNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSL 504 +GMTE F+ A LH + TVG P V+ KI K+G GEL IK ++ Sbjct: 303 FGMTETCSQFLTATPEMLHA--RPDTVGMPSANVDVKI----KNPNKEGHGELMIKGANV 356 Query: 505 FKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 Y ++T + G+F TGD +D +GY +I R Sbjct: 357 MNVYLYPTDLTGT--FENGYFNTGDIAEIDHEGYVMIYDR 394
>MENE_STAAS (Q6G8D6) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 492 Score = 50.1 bits (118), Expect = 6e-06 Identities = 34/100 (34%), Positives = 48/100 (48%), Gaps = 4/100 (4%) Frame = +1 Query: 337 YGMTE----FVMALSNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSL 504 +GMTE F+ A LH + TVG P V+ KI K+G GEL IK ++ Sbjct: 303 FGMTETCSQFLTATPEMLHA--RPDTVGMPSANVDVKI----KNPNKEGHGELMIKGANV 356 Query: 505 FKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 Y ++T + G+F TGD +D +GY +I R Sbjct: 357 MNGYLYPTDLTGT--FENGYFNTGDIAEIDHEGYVMIYDR 394
>MENE_STAAN (P63526) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 492 Score = 50.1 bits (118), Expect = 6e-06 Identities = 34/100 (34%), Positives = 48/100 (48%), Gaps = 4/100 (4%) Frame = +1 Query: 337 YGMTE----FVMALSNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSL 504 +GMTE F+ A LH + TVG P V+ KI K+G GEL IK ++ Sbjct: 303 FGMTETCSQFLTATPEMLHA--RPDTVGMPSANVDVKI----KNPNKEGHGELMIKGANV 356 Query: 505 FKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 Y ++T + G+F TGD +D +GY +I R Sbjct: 357 MNGYLYPTDLTGT--FENGYFNTGDIAEIDHEGYVMIYDR 394
>MENE_STAAM (P63525) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 492 Score = 50.1 bits (118), Expect = 6e-06 Identities = 34/100 (34%), Positives = 48/100 (48%), Gaps = 4/100 (4%) Frame = +1 Query: 337 YGMTE----FVMALSNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSL 504 +GMTE F+ A LH + TVG P V+ KI K+G GEL IK ++ Sbjct: 303 FGMTETCSQFLTATPEMLHA--RPDTVGMPSANVDVKI----KNPNKEGHGELMIKGANV 356 Query: 505 FKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 Y ++T + G+F TGD +D +GY +I R Sbjct: 357 MNGYLYPTDLTGT--FENGYFNTGDIAEIDHEGYVMIYDR 394
>MENE_STAAC (Q5HEY2) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 492 Score = 50.1 bits (118), Expect = 6e-06 Identities = 34/100 (34%), Positives = 48/100 (48%), Gaps = 4/100 (4%) Frame = +1 Query: 337 YGMTE----FVMALSNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSL 504 +GMTE F+ A LH + TVG P V+ KI K+G GEL IK ++ Sbjct: 303 FGMTETCSQFLTATPEMLHA--RPDTVGMPSANVDVKI----KNPNKEGHGELMIKGANV 356 Query: 505 FKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 Y ++T + G+F TGD +D +GY +I R Sbjct: 357 MNVYLYPTDLTGT--FENGYFNTGDIAEIDHEGYVMIYDR 394
>4CL_VANPL (O24540) 4-coumarate--CoA ligase (EC 6.2.1.12) (4CL)| (4-coumaroyl-CoA synthase) Length = 553 Score = 49.7 bits (117), Expect = 7e-06 Identities = 41/144 (28%), Positives = 65/144 (45%), Gaps = 12/144 (8%) Frame = +1 Query: 229 SYAAKQLRLMMCGSSALPSPLMKRWEEVTCHR-----LLERYGMTEFVMALSNPLHGAR- 390 +Y +R +M G++ PL K E+ + L + YGMTE L+ L A+ Sbjct: 305 NYDLSSVRTVMSGAA----PLGKELEDAVRAKFPNAKLGQGYGMTEAGPVLAMCLAFAKE 360 Query: 391 ----KEGTVGKPLPRVEAKIIMDDGTET--KDGVGELCIKSPSLFKEYWKRPEVTAESFI 552 K G G + E KI+ + + ++ GE+CI+ + K Y PE TA + Sbjct: 361 PFDIKSGACGTVVRNAEMKIVDPETGSSLPRNHPGEICIRGDQIMKGYLNDPEATARTID 420 Query: 553 DGGFFKTGDTVTVDEDGYFIILGR 624 G+ TGD +D+D I+ R Sbjct: 421 KEGWLHTGDIGYIDDDDELFIVDR 444
>ACSA_MYCTU (O69635) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 651 Score = 49.3 bits (116), Expect = 1e-05 Identities = 57/187 (30%), Positives = 83/187 (44%), Gaps = 20/187 (10%) Frame = +1 Query: 142 ITVFTGVPTVYTRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALP-SPLMKRWEEVTC 318 +T++ PT+ R+ + PD S+ LRL+ GS P +P RW Sbjct: 351 VTIYYTAPTLI-RMFMKWGREIPD-----SHDLSSLRLL--GSVGEPINPEAWRWYRDVI 402 Query: 319 HR----LLERYGMTEFVMALSNPLHG--ARKEGTVGKPLPRVEAKIIMDDG------TET 462 L++ + TE A+ +PL G A K G+ PLP + AKI+ D G TE Sbjct: 403 GGGRTPLVDTWWQTETGSAMISPLPGIAAAKPGSAMTPLPGISAKIVDDHGDPLPPHTEG 462 Query: 463 KDGV-GELCIKSP--SLFKEYWKRPEVTAES----FIDGGFFKTGDTVTVDEDGYFIILG 621 V G L + P S+ + W P S F D G++ GD +D DG +LG Sbjct: 463 AQHVTGYLVLDQPWPSMLRGIWGDPARYWHSYWSKFSDKGYYFAGDGARIDPDGAIWVLG 522 Query: 622 RTNADIM 642 R + D+M Sbjct: 523 RID-DVM 528
>ACSA_MYCBO (P59871) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 651 Score = 49.3 bits (116), Expect = 1e-05 Identities = 57/187 (30%), Positives = 83/187 (44%), Gaps = 20/187 (10%) Frame = +1 Query: 142 ITVFTGVPTVYTRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALP-SPLMKRWEEVTC 318 +T++ PT+ R+ + PD S+ LRL+ GS P +P RW Sbjct: 351 VTIYYTAPTLI-RMFMKWGREIPD-----SHDLSSLRLL--GSVGEPINPEAWRWYRDVI 402 Query: 319 HR----LLERYGMTEFVMALSNPLHG--ARKEGTVGKPLPRVEAKIIMDDG------TET 462 L++ + TE A+ +PL G A K G+ PLP + AKI+ D G TE Sbjct: 403 GGGRTPLVDTWWQTETGSAMISPLPGIAAAKPGSAMTPLPGISAKIVDDHGDPLPPHTEG 462 Query: 463 KDGV-GELCIKSP--SLFKEYWKRPEVTAES----FIDGGFFKTGDTVTVDEDGYFIILG 621 V G L + P S+ + W P S F D G++ GD +D DG +LG Sbjct: 463 AQHVTGYLVLDQPWPSMLRGIWGDPARYWHSYWSKFSDKGYYFAGDGARIDPDGAIWVLG 522 Query: 622 RTNADIM 642 R + D+M Sbjct: 523 RID-DVM 528
>DLTA_STRP6 (Q5XBN5) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 512 Score = 49.3 bits (116), Expect = 1e-05 Identities = 39/134 (29%), Positives = 57/134 (42%), Gaps = 9/134 (6%) Frame = +1 Query: 265 GSSALPSPLMKRWEEVTCHRLLERYGMTEFVMALS-----NPLHGARKEGTVGKPLPRVE 429 G S K +E +++ YG TE +ALS + +G P P Sbjct: 272 GEELTVSTARKLFERFPSAKIINAYGPTEATVALSAIEITREMVDNYTRLPIGYPKPDSP 331 Query: 430 AKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFI---DGGFFKTGDTVTVDE 597 II +DG E G GE+ + P++ K Y PE TAE+F + TGD ++ E Sbjct: 332 TYIIDEDGKELSSGEQGEIIVTGPAVSKGYLNNPEKTAEAFFTFKGQPAYHTGDIGSLTE 391 Query: 598 DGYFIILGRTNADI 639 D + GR + I Sbjct: 392 DNILLYGGRLDFQI 405
>DLTA_STRP3 (Q8K744) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 512 Score = 49.3 bits (116), Expect = 1e-05 Identities = 39/134 (29%), Positives = 57/134 (42%), Gaps = 9/134 (6%) Frame = +1 Query: 265 GSSALPSPLMKRWEEVTCHRLLERYGMTEFVMALS-----NPLHGARKEGTVGKPLPRVE 429 G S K +E +++ YG TE +ALS + +G P P Sbjct: 272 GEELTVSTARKLFERFPSAKIINAYGPTEATVALSAIEITREMVDNYTRLPIGYPKPDSP 331 Query: 430 AKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFI---DGGFFKTGDTVTVDE 597 II +DG E G GE+ + P++ K Y PE TAE+F + TGD ++ E Sbjct: 332 TYIIDEDGKELSSGEQGEIIVTGPAVSKGYLNNPEKTAEAFFTFKGQPAYHTGDIGSLTE 391 Query: 598 DGYFIILGRTNADI 639 D + GR + I Sbjct: 392 DNILLYGGRLDFQI 405
>DLTA_STRP1 (Q99ZA6) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 512 Score = 49.3 bits (116), Expect = 1e-05 Identities = 39/134 (29%), Positives = 57/134 (42%), Gaps = 9/134 (6%) Frame = +1 Query: 265 GSSALPSPLMKRWEEVTCHRLLERYGMTEFVMALS-----NPLHGARKEGTVGKPLPRVE 429 G S K +E +++ YG TE +ALS + +G P P Sbjct: 272 GEELTVSTARKLFERFPSAKIINAYGPTEATVALSAIEITREMVDNYTRLPIGYPKPDSP 331 Query: 430 AKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFI---DGGFFKTGDTVTVDE 597 II +DG E G GE+ + P++ K Y PE TAE+F + TGD ++ E Sbjct: 332 TYIIDEDGKELSSGEQGEIIVTGPAVSKGYLNNPEKTAEAFFTFKGQPAYHTGDIGSLTE 391 Query: 598 DGYFIILGRTNADI 639 D + GR + I Sbjct: 392 DNILLYGGRLDFQI 405
>DLTA_STRP8 (Q8P0J9) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 512 Score = 48.9 bits (115), Expect = 1e-05 Identities = 39/134 (29%), Positives = 57/134 (42%), Gaps = 9/134 (6%) Frame = +1 Query: 265 GSSALPSPLMKRWEEVTCHRLLERYGMTEFVMALS-----NPLHGARKEGTVGKPLPRVE 429 G S K +E +++ YG TE +ALS + +G P P Sbjct: 272 GEELTVSTARKLFERFPSAKIINAYGPTEATVALSAIEITREMVDNYTRLPIGYPKPDSP 331 Query: 430 AKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFI---DGGFFKTGDTVTVDE 597 II +DG E G GE+ + P++ K Y PE TAE+F + TGD ++ E Sbjct: 332 TYIIDEDGKELASGEQGEIIVTGPAVSKGYLNNPEKTAEAFFTFKGQPAYHTGDIGSLTE 391 Query: 598 DGYFIILGRTNADI 639 D + GR + I Sbjct: 392 DNILLYGGRLDFQI 405
>MENE_STAAR (Q6GFR0) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 492 Score = 48.9 bits (115), Expect = 1e-05 Identities = 34/100 (34%), Positives = 47/100 (47%), Gaps = 4/100 (4%) Frame = +1 Query: 337 YGMTE----FVMALSNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSL 504 +GMTE F+ A LH + TVG P V+ KI K G GEL IK ++ Sbjct: 303 FGMTETCSQFLTATPEMLHA--RPDTVGMPSANVDVKI----KNPNKKGHGELMIKGANV 356 Query: 505 FKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 Y ++T + G+F TGD +D +GY +I R Sbjct: 357 MNGYLYPTDLTGT--FENGYFNTGDIAEIDHEGYVMIYDR 394
>4CL1_ORYSA (P17814) 4-coumarate--CoA ligase 1 (EC 6.2.1.12) (4CL 1)| (4-coumaroyl-CoA synthase 1) Length = 564 Score = 48.9 bits (115), Expect = 1e-05 Identities = 42/148 (28%), Positives = 68/148 (45%), Gaps = 12/148 (8%) Frame = +1 Query: 217 QSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCHRLL-----ERYGMTEFVMALSNPLH 381 ++A + +R+++ G++ P+ K E+ +L + YGMTE LS L Sbjct: 312 EAAAARDLSSVRMVLSGAA----PMGKDIEDAFMAKLPGAVLGQGYGMTEAGPVLSMCLA 367 Query: 382 GAR-----KEGTVGKPLPRVEAKIIMDDGTET--KDGVGELCIKSPSLFKEYWKRPEVTA 540 A+ K G G + E KII D ++ ++ GE+CI+ + K Y PE T Sbjct: 368 FAKEPFKVKSGACGTVVRNAELKIIDPDTGKSLGRNLPGEICIRGQQIMKGYLNNPEATK 427 Query: 541 ESFIDGGFFKTGDTVTVDEDGYFIILGR 624 + G+ TGD VD+D I+ R Sbjct: 428 NTIDAEGWLHTGDIGYVDDDDEIFIVDR 455
>4CL2_TOBAC (O24146) 4-coumarate--CoA ligase 2 (EC 6.2.1.12) (4CL 2)| (4-coumaroyl-CoA synthase 2) Length = 542 Score = 48.5 bits (114), Expect = 2e-05 Identities = 41/143 (28%), Positives = 63/143 (44%), Gaps = 12/143 (8%) Frame = +1 Query: 232 YAAKQLRLMMCGSSALPSPLMKRWEEVTCHR-----LLERYGMTEFVMALSNPLHGAR-- 390 Y +R +M G++ PL K E+ + L + YGMTE L+ L A+ Sbjct: 297 YDLSSVRTVMSGAA----PLGKELEDTVRAKFPNAKLGQGYGMTEAGPVLAMCLAFAKEP 352 Query: 391 ---KEGTVGKPLPRVEAKII--MDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFID 555 K G G + E KI+ + ++ GE+CI+ + K Y PE TA + Sbjct: 353 FEIKSGACGTVVRNAEMKIVDPKTGNSLPRNQSGEICIRGDQIMKGYLNDPEATARTIDK 412 Query: 556 GGFFKTGDTVTVDEDGYFIILGR 624 G+ TGD +D+D I+ R Sbjct: 413 EGWLYTGDIGYIDDDDELFIVDR 435
>PKSJ_BACSU (P40806) Putative polyketide synthase pksJ (PKS)| Length = 5045 Score = 48.1 bits (113), Expect = 2e-05 Identities = 38/136 (27%), Positives = 59/136 (43%), Gaps = 8/136 (5%) Frame = +1 Query: 256 MMCGSSALPSPLMKRWEEVTCHRLLERYGMTEF-VMALSNPLHGARKEGTVGKPLPRVEA 432 ++CG ALP L KR+ T +G TE + + ++ T+G+P+ + Sbjct: 1419 ILCGGEALPETL-KRYFLDTGSEAWNMFGPTETTIWSAVQRINVECSHATIGRPIANTQI 1477 Query: 433 KIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTV 591 I GV GELCI + K Y+K+ E+T FID F ++TGD Sbjct: 1478 YITDSQLAPVPAGVPGELCIAGDGVAKGYYKKEELTDSRFIDNPFEPGSKLYRTGDMARW 1537 Query: 592 DEDGYFIILGRTNADI 639 G +GR + + Sbjct: 1538 LTGGRIEYIGRIDNQV 1553 Score = 42.7 bits (99), Expect = 0.001 Identities = 23/81 (28%), Positives = 42/81 (51%), Gaps = 1/81 (1%) Frame = +1 Query: 403 VGKPLPRVEAKIIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGD 579 +G P+P +I+ D ++G +G + S+ Y++RP++ F + G+F+TGD Sbjct: 376 IGSPIPGFSMRIVNDHNELVEEGEIGRFQVSGLSVTSGYYQRPDLNESVFTEDGWFETGD 435 Query: 580 TVTVDEDGYFIILGRTNADIM 642 + +G I GRT I+ Sbjct: 436 LGFL-RNGRLTITGRTKDAII 455
>MENE_STAES (Q8CS21) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 474 Score = 48.1 bits (113), Expect = 2e-05 Identities = 40/130 (30%), Positives = 62/130 (47%), Gaps = 4/130 (3%) Frame = +1 Query: 247 LRLMMCGSSALPSPLMKRWEEVTCHRL--LERYGMTEFVMAL--SNPLHGARKEGTVGKP 414 L ++ G + L L+ E+ +RL +GMTE ++P + TVGK Sbjct: 245 LEKILLGGAKLSPQLI---EQAFAYRLPVYNSFGMTETCSQFLTASPQMLKERFDTVGKT 301 Query: 415 LPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVD 594 VE KI + G GEL IK ++ Y P+ ++F + G+F+TGD +D Sbjct: 302 SENVEVKIKNPNAY----GHGELLIKGENVMNGYLY-PKYLKDTFDNDGYFQTGDIAEID 356 Query: 595 EDGYFIILGR 624 ++GY II R Sbjct: 357 DEGYVIIYDR 366
>4CL4_ARATH (Q9LU36) 4-coumarate--CoA ligase 4 (EC 6.2.1.12) (4CL 4) (At4CL4)| (4-coumaroyl-CoA synthase 4) (4-coumarate CoA ligase isoform 5) Length = 570 Score = 48.1 bits (113), Expect = 2e-05 Identities = 40/143 (27%), Positives = 61/143 (42%), Gaps = 12/143 (8%) Frame = +1 Query: 232 YAAKQLRLMMCGSSALPSPLMKRWEEVTCHRLL-ERYGMTEF------VMALSNPLHGAR 390 Y +R+M+ G++ L L + + + YGMTE + NP Sbjct: 326 YDLSSVRIMLSGAATLKKELEDAVRLKFPNAIFGQGYGMTESGTVAKSLAFAKNPFK--T 383 Query: 391 KEGTVGKPLPRVEAKIIMDDGTET-----KDGVGELCIKSPSLFKEYWKRPEVTAESFID 555 K G G + E K++ TET ++ GE+C++ L K Y PE TA + Sbjct: 384 KSGACGTVIRNAEMKVV---DTETGISLPRNKSGEICVRGHQLMKGYLNDPEATARTIDK 440 Query: 556 GGFFKTGDTVTVDEDGYFIILGR 624 G+ TGD VD+D I+ R Sbjct: 441 DGWLHTGDIGFVDDDDEIFIVDR 463
>ORA_PLAFN (P16405) Octapeptide-repeat antigen (ORA) (Fragment)| Length = 701 Score = 47.8 bits (112), Expect = 3e-05 Identities = 22/51 (43%), Positives = 32/51 (62%) Frame = +1 Query: 475 GELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRT 627 GEL IKS S+F Y+ E T +F + G+FKTGD V ++++G L R+ Sbjct: 436 GELLIKSDSMFSGYFLEKESTEHAFTNDGYFKTGDIVQINDNGSLTFLDRS 486
>4CL2_PETCR (P14913) 4-coumarate--CoA ligase 1 (EC 6.2.1.12) (4CL 1)| (4-coumaroyl-CoA synthase 1) Length = 544 Score = 47.4 bits (111), Expect = 4e-05 Identities = 40/143 (27%), Positives = 64/143 (44%), Gaps = 12/143 (8%) Frame = +1 Query: 232 YAAKQLRLMMCGSSALPSPLMKRWEEVTCHR-----LLERYGMTEFVMALSNPLHGAR-- 390 Y +R +M G++ PL K E+ + L + YGMTE L+ L A+ Sbjct: 298 YDLSSVRTVMSGAA----PLGKELEDAVRAKFPNAKLGQGYGMTEAGPVLAMCLAFAKEP 353 Query: 391 ---KEGTVGKPLPRVEAKIIMDDGTET--KDGVGELCIKSPSLFKEYWKRPEVTAESFID 555 K G G + E KI+ + + ++ GE+CI+ + K Y PE T + + Sbjct: 354 YEIKSGACGTVVRNAEMKIVDPETNASLPRNQRGEICIRGDQIMKGYLNDPESTRTTIDE 413 Query: 556 GGFFKTGDTVTVDEDGYFIILGR 624 G+ TGD +D+D I+ R Sbjct: 414 EGWLHTGDIGFIDDDDELFIVDR 436
>4CL1_PETCR (P14912) 4-coumarate--CoA ligase 1 (EC 6.2.1.12) (4CL 1)| (4-coumaroyl-CoA synthase 1) Length = 544 Score = 47.4 bits (111), Expect = 4e-05 Identities = 40/143 (27%), Positives = 64/143 (44%), Gaps = 12/143 (8%) Frame = +1 Query: 232 YAAKQLRLMMCGSSALPSPLMKRWEEVTCHR-----LLERYGMTEFVMALSNPLHGAR-- 390 Y +R +M G++ PL K E+ + L + YGMTE L+ L A+ Sbjct: 298 YDLSSVRTVMSGAA----PLGKELEDAVRAKFPNAKLGQGYGMTEAGPVLAMCLAFAKEP 353 Query: 391 ---KEGTVGKPLPRVEAKIIMDDGTET--KDGVGELCIKSPSLFKEYWKRPEVTAESFID 555 K G G + E KI+ + + ++ GE+CI+ + K Y PE T + + Sbjct: 354 YEIKSGACGTVVRNAEMKIVDPETNASLPRNQRGEICIRGDQIMKGYLNDPESTRTTIDE 413 Query: 556 GGFFKTGDTVTVDEDGYFIILGR 624 G+ TGD +D+D I+ R Sbjct: 414 EGWLHTGDIGFIDDDDELFIVDR 436
>ACSA_PYRAE (O93730) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 670 Score = 47.0 bits (110), Expect = 5e-05 Identities = 30/85 (35%), Positives = 41/85 (48%), Gaps = 5/85 (5%) Frame = +1 Query: 391 KEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSP--SLFKEYWKRPEVTAESFIDG- 558 K GT G PLP E ++ ++G GV G L IK P + W PE +++ Sbjct: 450 KPGTNGPPLPGFEVDVVDENGNPAPPGVKGYLVIKKPWPGMLHGIWGDPERYIKTYWSRF 509 Query: 559 -GFFKTGDTVTVDEDGYFIILGRTN 630 G F GD D+DGY +LGR + Sbjct: 510 PGMFYAGDYAIKDKDGYIWVLGRAD 534
>DLTA_LACRH (P35854) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 506 Score = 47.0 bits (110), Expect = 5e-05 Identities = 37/140 (26%), Positives = 60/140 (42%), Gaps = 12/140 (8%) Frame = +1 Query: 256 MMCGSSAL---PSPLMKRWEEVTCHRLLERYGMTEFV-----MALSNPLHGARKEGTVGK 411 + CG + L+ R+ + T + YG TE MA++ + +G Sbjct: 267 LFCGEELVNKTAQALITRFPKATVYNT---YGPTEATVAVTGMAITQAIVDQYPRLPIGY 323 Query: 412 PLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGG---FFKTGD 579 P ++ + G + G GEL I PS+ K Y P+ TA +F G +++GD Sbjct: 324 AKPDTNVYVVDEQGEQVSAGTEGELMIVGPSVSKGYLNNPDKTAAAFFKAGNQRGYRSGD 383 Query: 580 TVTVDEDGYFIILGRTNADI 639 VT+ DG GRT+ + Sbjct: 384 LVTMTADGMVFYRGRTDFQV 403
>ENTF_ECOLI (P11454) Enterobactin synthetase component F (EC 2.7.7.-)| (Enterochelin synthase F) (Serine-activating enzyme) (Seryl-AMP ligase) Length = 1293 Score = 46.6 bits (109), Expect = 6e-05 Identities = 41/142 (28%), Positives = 67/142 (47%), Gaps = 14/142 (9%) Frame = +1 Query: 247 LRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEFVMALS-NPLHG---ARKEGT---V 405 L+ + C ALP+ L + W+++T L YG TE + +S P G A+ G+ + Sbjct: 716 LKQVFCSGEALPADLCREWQQLTGAPLHNLYGPTEAAVDVSWYPAFGEELAQVRGSSVPI 775 Query: 406 GKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF------ 564 G P+ +I+ GV G+L + L + Y RP++TA FI F Sbjct: 776 GYPVWNTGLRILDAMMHPVPPGVAGDLYLTGIQLAQGYLGRPDLTASRFIADPFAPGERM 835 Query: 565 FKTGDTVTVDEDGYFIILGRTN 630 ++TGD ++G LGR++ Sbjct: 836 YRTGDVARWLDNGAVEYLGRSD 857
>ENTF_ECO57 (Q8XBV9) Enterobactin synthetase component F (EC 2.7.7.-)| (Enterochelin synthase F) (Serine-activating enzyme) (Seryl-AMP ligase) Length = 1293 Score = 46.6 bits (109), Expect = 6e-05 Identities = 41/142 (28%), Positives = 67/142 (47%), Gaps = 14/142 (9%) Frame = +1 Query: 247 LRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEFVMALS-NPLHG---ARKEGT---V 405 L+ + C ALP+ L + W+++T L YG TE + +S P G A+ G+ + Sbjct: 716 LKQVFCSGEALPADLCREWQQLTGAPLHNLYGPTEAAVDVSWYPAFGEELAQVRGSSVPI 775 Query: 406 GKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF------ 564 G P+ +I+ GV G+L + L + Y RP++TA FI F Sbjct: 776 GYPVWNTGLRILDAMMHPVPPGVAGDLYLTGIQLAQGYLGRPDLTASRFIADPFVPGERM 835 Query: 565 FKTGDTVTVDEDGYFIILGRTN 630 ++TGD ++G LGR++ Sbjct: 836 YRTGDVARWLDNGAVEYLGRSD 857
>DLTA_STRR6 (P0A399) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 516 Score = 46.6 bits (109), Expect = 6e-05 Identities = 34/115 (29%), Positives = 55/115 (47%), Gaps = 9/115 (7%) Frame = +1 Query: 322 RLLERYGMTEFVMALS-----NPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGV-GEL 483 R++ YG TE +ALS + + K +G II ++G + +G GE+ Sbjct: 295 RIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADSPTFIIDEEGNKLPNGEQGEI 354 Query: 484 CIKSPSLFKEYWKRPEVTAESFI---DGGFFKTGDTVTVDEDGYFIILGRTNADI 639 + P++ K Y PE TAE+F D + TGD T+ ++G + GR + I Sbjct: 355 IVSGPAVSKGYMNNPEKTAEAFFEFEDLPAYHTGDVGTMTDEGLLLYGGRMDFQI 409
>DLTA_STRPN (P0A398) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 516 Score = 46.6 bits (109), Expect = 6e-05 Identities = 34/115 (29%), Positives = 55/115 (47%), Gaps = 9/115 (7%) Frame = +1 Query: 322 RLLERYGMTEFVMALS-----NPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGV-GEL 483 R++ YG TE +ALS + + K +G II ++G + +G GE+ Sbjct: 295 RIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADSPTFIIDEEGNKLPNGEQGEI 354 Query: 484 CIKSPSLFKEYWKRPEVTAESFI---DGGFFKTGDTVTVDEDGYFIILGRTNADI 639 + P++ K Y PE TAE+F D + TGD T+ ++G + GR + I Sbjct: 355 IVSGPAVSKGYMNNPEKTAEAFFEFEDLPAYHTGDVGTMTDEGLLLYGGRMDFQI 409
>ENTF_SHIFL (P29698) Enterobactin synthetase component F (EC 2.7.7.-)| (Enterochelin synthase F) (Serine-activating enzyme) (Seryl-AMP ligase) Length = 1281 Score = 46.6 bits (109), Expect = 6e-05 Identities = 41/142 (28%), Positives = 67/142 (47%), Gaps = 14/142 (9%) Frame = +1 Query: 247 LRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEFVMALS-NPLHG---ARKEGT---V 405 L+ + C ALP+ L + W+++T L YG TE + +S P G A+ G+ + Sbjct: 720 LKQVFCSGEALPADLCREWQQLTGAPLHNLYGPTEAAVDVSWYPAFGEELAQVRGSSVPI 779 Query: 406 GKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF------ 564 G P+ +I+ GV G+L + L + Y RP++TA FI F Sbjct: 780 GYPVWNTGLRILDAMMHPVPPGVAGDLYLTGIQLAQGYLGRPDLTASRFIADPFAPGERM 839 Query: 565 FKTGDTVTVDEDGYFIILGRTN 630 ++TGD ++G LGR++ Sbjct: 840 YRTGDVARWLDNGAVEYLGRSD 861
>LCF1_YEAST (P30624) Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 1) (Fatty acid activator 1) Length = 700 Score = 45.4 bits (106), Expect = 1e-04 Identities = 38/130 (29%), Positives = 62/130 (47%), Gaps = 3/130 (2%) Frame = +1 Query: 244 QLRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEFVMALSNPLHGARKE-GTVGKPLP 420 QLR ++ G S + + + C L+ YG+TE A + L A E G G Sbjct: 426 QLRYLLNGGSPISRDAQEFITNLICPMLIG-YGLTE-TCASTTILDPANFELGVAGDLTG 483 Query: 421 RVEAKIIMDD--GTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVD 594 V K++ + G K+ GE+ I ++ EY+K E T+++ G+FKTGD + Sbjct: 484 CVTVKLVDVEELGYFAKNNQGEVWITGANVTPEYYKNEEETSQALTSDGWFKTGDIGEWE 543 Query: 595 EDGYFIILGR 624 +G+ I+ R Sbjct: 544 ANGHLKIIDR 553
>ACSA_CHLTE (Q8KBY0) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 659 Score = 45.4 bits (106), Expect = 1e-04 Identities = 36/111 (32%), Positives = 57/111 (51%), Gaps = 9/111 (8%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLHGAR--KEGTVGKPLPRVEAKIIMDDGT--ETKDGVGELCIK 492 +++ + TE + +P+ GA K GT +PLP + ++ DGT +G G L +K Sbjct: 421 IVDTWWQTETGGIMISPMPGATPTKPGTATRPLPGIMVDVVRKDGTPCNANEG-GYLVVK 479 Query: 493 SP--SLFKEYW---KRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTN 630 P S+ + + +R E T S G +F TGD D+DGY I+GR + Sbjct: 480 RPWPSMLRTIYGDNERYEKTYWSEFPGMYF-TGDGARKDDDGYIWIMGRVD 529
>ACSA_LEPIN (Q8EYG2) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 661 Score = 45.4 bits (106), Expect = 1e-04 Identities = 34/111 (30%), Positives = 55/111 (49%), Gaps = 9/111 (8%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLHGA--RKEGTVGKPLPRVEAKIIMDDGTETKDG---VGELCI 489 +++ + TE + L GA +K G+ P V+ ++ +DG E D G LCI Sbjct: 418 IVDTWWQTETGSIMITALPGAIPQKPGSATLPFFGVQPVLVDNDGKEITDKGEVSGNLCI 477 Query: 490 KSP--SLFKEYWKRPEVTAESFIDG--GFFKTGDTVTVDEDGYFIILGRTN 630 K P S+ + + P+ E++ G++ TGD D+DGYF I GR + Sbjct: 478 KGPWPSMMRGVYGDPKRFFETYFSQFKGYYFTGDGARRDKDGYFWITGRVD 528
>ACSA_LEPIC (Q72LY9) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 661 Score = 45.4 bits (106), Expect = 1e-04 Identities = 34/111 (30%), Positives = 55/111 (49%), Gaps = 9/111 (8%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLHGA--RKEGTVGKPLPRVEAKIIMDDGTETKDG---VGELCI 489 +++ + TE + L GA +K G+ P V+ ++ +DG E D G LCI Sbjct: 418 IVDTWWQTETGSIMITALPGAIPQKPGSATLPFFGVQPVLVDNDGKEITDKGEVSGNLCI 477 Query: 490 KSP--SLFKEYWKRPEVTAESFIDG--GFFKTGDTVTVDEDGYFIILGRTN 630 K P S+ + + P+ E++ G++ TGD D+DGYF I GR + Sbjct: 478 KGPWPSMMRGVYGDPKRFFETYFSQFKGYYFTGDGARRDKDGYFWITGRVD 528
>ACS1_YEAST (Q01574) Acetyl-coenzyme A synthetase 1 (EC 6.2.1.1) (Acetate--CoA| ligase 1) (Acyl-activating enzyme 1) Length = 713 Score = 45.4 bits (106), Expect = 1e-04 Identities = 33/113 (29%), Positives = 55/113 (48%), Gaps = 11/113 (9%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLHGA---RKEGTVGKPLPRVEAKIIMDDGT----ETKDGVGEL 483 +++ Y TE L PL G K G+ P ++A +++D T T G L Sbjct: 465 IVDTYWQTESGSHLVTPLAGGVTPMKPGSASFPFFGIDA-VVLDPNTGEELNTSHAEGVL 523 Query: 484 CIKS--PSLFKEYWKRPEVTAESFIDG--GFFKTGDTVTVDEDGYFIILGRTN 630 +K+ PS + WK + +++++ G++ TGD D+DGY ILGR + Sbjct: 524 AVKAAWPSFARTIWKNHDRYLDTYLNPYPGYYFTGDGAAKDKDGYIWILGRVD 576
>VIBE_VIBCH (O07899) Vibriobactin-specific 2,3-dihydroxybenzoate-AMP ligase (EC| 6.3.2.-) (Dihydroxybenzoic acid-activating enzyme) Length = 543 Score = 45.1 bits (105), Expect = 2e-04 Identities = 33/146 (22%), Positives = 61/146 (41%), Gaps = 3/146 (2%) Frame = +1 Query: 211 DQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEFVMALSNPLHGAR 390 D +Y L + G + +R + +L + +GM E ++ + A Sbjct: 292 DHAEKSTYDLSSLHFVQVGGAKFSEAAARRLPKALGCQLQQVFGMAEGLVNYTRLDDSAE 351 Query: 391 KEGTV-GKPLPRVEAKIIMDD-GTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGG 561 T G+P+ + +++D+ G G G L + P + Y++ + +F G Sbjct: 352 LIATTQGRPISAHDQLLVVDEQGQPVASGEEGYLLTQGPYTIRGYYRADQHNQRAFNAQG 411 Query: 562 FFKTGDTVTVDEDGYFIILGRTNADI 639 F+ TGD V + +GY I+ GR I Sbjct: 412 FYITGDKVKLSSEGYVIVTGRAKDQI 437
>LUCI_PHOPE (Q27757) Luciferin 4-monooxygenase (EC 1.13.12.7) (Luciferase)| Length = 545 Score = 45.1 bits (105), Expect = 2e-04 Identities = 35/123 (28%), Positives = 54/123 (43%), Gaps = 9/123 (7%) Frame = +1 Query: 283 SPLMKRWEEVTCHR-----LLERYGMTEFVMALSNPLHGARKEGTVGKPLPRVEAKIIMD 447 +PL K E+ R + + YG+TE A+ + G+ GK +P K++ Sbjct: 316 APLSKEIGEMVKKRFKLNFVRQGYGLTETTSAVLITPDTDVRPGSTGKIVPFHAVKVV-- 373 Query: 448 DGTETK----DGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFII 615 D T K + GEL K + K Y+ E T G+ ++GD D DG+F I Sbjct: 374 DPTTGKILGPNETGELYFKGDMIMKSYYNNEEATKAIINKDGWLRSGDIAYYDNDGHFYI 433 Query: 616 LGR 624 + R Sbjct: 434 VDR 436
>ACSA_STRAW (Q82EL5) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 652 Score = 44.7 bits (104), Expect = 2e-04 Identities = 31/114 (27%), Positives = 57/114 (50%), Gaps = 8/114 (7%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKS- 495 +++ + TE + +PL G K G+ +PLP + A ++ D+ E +G G + + Sbjct: 410 IVDTWWQTETGAMMISPLPGVTETKPGSAQRPLPGISATVVDDEAREVPNGGGGYLVLTE 469 Query: 496 --PSLFKEYWKRPEVTAESF---IDGGFFKTGDTVTVDEDGYFIILGRTNADIM 642 PS+ + W + +++ +G +F GD DEDG +LGR + D+M Sbjct: 470 PWPSMLRTIWGDDQRFLDTYWSRFEGKYF-AGDGAKKDEDGDIWLLGRVD-DVM 521
>LCF2_YEAST (P39518) Long-chain-fatty-acid--CoA ligase 2 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 2) (Fatty acid activator 2) Length = 744 Score = 44.7 bits (104), Expect = 2e-04 Identities = 20/54 (37%), Positives = 31/54 (57%) Frame = +1 Query: 463 KDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 KD GEL I+ P +F+ Y+K P T+++ G+F TGD +D G ++ R Sbjct: 536 KDLKGELQIRGPQVFERYFKNPNETSKAVDQDGWFSTGDVAFIDGKGRISVIDR 589
>ACVS_NOCLA (P27743) N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase| (EC 6.3.2.26) (Delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase) (ACV synthetase) (ACVS) Length = 3649 Score = 44.3 bits (103), Expect = 3e-04 Identities = 36/120 (30%), Positives = 51/120 (42%), Gaps = 15/120 (12%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLH----GARKEGTVGKPLPRVEAKIIMDDGTETKDG-VGELCI 489 +L YG TE + N +H G T+G PL ++ D G VGEL + Sbjct: 2683 ILNAYGTTE--TTVYNTVHRFEPGDAYRNTLGAPLGNTRLYVLGDGMKLLPTGAVGELYL 2740 Query: 490 KSPSLFKEYWKRPEVTAESFIDGGF----------FKTGDTVTVDEDGYFIILGRTNADI 639 + + Y RPE+T E F+ F ++TGD V DG LGR +A + Sbjct: 2741 AGDCVTEGYLHRPELTRERFLPNPFAAESGRFPMIYRTGDVVRRGPDGELQYLGRNDAQV 2800 Score = 38.5 bits (88), Expect = 0.017 Identities = 38/146 (26%), Positives = 64/146 (43%), Gaps = 19/146 (13%) Frame = +1 Query: 250 RLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTE--FVMALSN--PLHGARKEGTVGKPL 417 RL++ G S L ++ E R++ Y TE FV A+ P R++ ++G+PL Sbjct: 519 RLLLVGEELTASGL-RQLREKFAGRVVNEYAFTEAAFVTAVKEFGPGVTERRDRSIGRPL 577 Query: 418 PRVEAKIIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESFI-------------- 552 V+ ++ + G +GEL I + Y R ++TAE F Sbjct: 578 RNVKWYVLSQGLKQLPIGAIGELYIGGCGVAPGYLNRDDLTAERFTANPFQTEEEKARGR 637 Query: 553 DGGFFKTGDTVTVDEDGYFIILGRTN 630 +G ++TGD V +G +GR + Sbjct: 638 NGRLYRTGDLARVLLNGEVEFMGRAD 663 Score = 37.0 bits (84), Expect = 0.050 Identities = 43/188 (22%), Positives = 71/188 (37%), Gaps = 18/188 (9%) Frame = +1 Query: 130 NDEAITVFTGVPTVYTRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEE 309 NDE +T +G P+V + L Y S A R+ G P+ + Sbjct: 1581 NDEQVTYLSGTPSVLS--LYDYSS-----------ATSLTRIDAIGED-FTEPVFAKIRG 1626 Query: 310 VTCHRLLERYGMTEFVMALSN---PLHGARKEGTVGKPLPRVEAKIIMDDGTETK-DGVG 477 ++ YG TE + P R ++G P+ + ++ G+G Sbjct: 1627 TFPGLIINGYGPTEISITSHKRPYPPDVHRVNKSIGFPVANTKCHVLNKAMKPVPVGGIG 1686 Query: 478 ELCIKSPSLFKEYWKRPEVTAESFIDGGF--------------FKTGDTVTVDEDGYFII 615 EL I + + Y R ++TA+ F++ F +KTGD V +G Sbjct: 1687 ELYIGGIGVTRGYLNREDLTADRFVENPFQTAEERRLGENGRLYKTGDLVRWLPNGEVEY 1746 Query: 616 LGRTNADI 639 LGRT+ + Sbjct: 1747 LGRTDLQV 1754
>4CL1_SOYBN (P31686) 4-coumarate--CoA ligase 1 (EC 6.2.1.12) (4CL 1)| (4-coumaroyl-CoA synthase 1) (Clone 4CL14) (Fragment) Length = 293 Score = 43.9 bits (102), Expect = 4e-04 Identities = 44/173 (25%), Positives = 72/173 (41%), Gaps = 12/173 (6%) Frame = +1 Query: 142 ITVFTGVPTVYTRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCH 321 +T+ VP + + S +PD Y +R++ G + PL K E+ Sbjct: 25 VTIAPVVPPIVLAI-----SKSPDLHK---YDLSSIRVLKSGGA----PLGKELEDTLRA 72 Query: 322 R-----LLERYGMTEFVMALSNPLHGAR-----KEGTVGKPLPRVEAKIIMDDGTET--K 465 + L + YGMTE L+ L A+ K G G + E KI+ + + + Sbjct: 73 KFPNAKLGQGYGMTEAGPVLTMSLAFAKEPIDVKPGACGTVVRNAEMKIVDPETGHSLPR 132 Query: 466 DGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 + GE+CI+ + K Y E T + G+ TGD +D+D I+ R Sbjct: 133 NQSGEICIRGDQIMKGYLNDGEATERTIDKDGWLHTGDIGYIDDDDELFIVDR 185
>SRFAB_BACSU (Q04747) Surfactin synthetase subunit 2| Length = 3587 Score = 43.9 bits (102), Expect = 4e-04 Identities = 37/148 (25%), Positives = 64/148 (43%), Gaps = 15/148 (10%) Frame = +1 Query: 241 KQLRLMMCGSSALPSPLMKRWEEVTCH-RLLERYGMTEFVMA-------LSNPLHGARKE 396 + LRL++ G + + + ++ H + YG TE + L P K Sbjct: 1760 ESLRLIVLGGEKIIPTDVIAFRKMYGHTEFINHYGPTEATIGAIAGRVDLYEP-DAFAKR 1818 Query: 397 GTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF--- 564 T+G+P+ A ++ + G G+L I L + Y RP++TAE F++ + Sbjct: 1819 PTIGRPIANAGALVLNEALKLVPPGASGQLYITGQGLARGYLNRPQLTAERFVENPYSPG 1878 Query: 565 ---FKTGDTVTVDEDGYFIILGRTNADI 639 +KTGD V DG +GR + + Sbjct: 1879 SLMYKTGDVVRRLSDGTLAFIGRADDQV 1906 Score = 37.4 bits (85), Expect = 0.038 Identities = 36/141 (25%), Positives = 62/141 (43%), Gaps = 10/141 (7%) Frame = +1 Query: 247 LRLMMCGSSALPSPLMKRWEEVTCH-RLLERYGMTEFVMALSNPLHGARKEGTV--GKPL 417 LR ++ G AL ++ + ++ + L YG TE ++ L G++ GKP+ Sbjct: 721 LRHLIIGGDALVPHIVSKVKQASPSLSLWNGYGPTENTTFSTSFLIDREYGGSIPIGKPI 780 Query: 418 PRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTG 576 A I+ + G GELC+ + + Y PE+T + F++ F ++TG Sbjct: 781 GNSTAYIMDEQQCLQPIGAPGELCVGGIGVARGYVNLPELTEKQFLEDPFRPGERIYRTG 840 Query: 577 DTVTVDEDGYFIILGRTNADI 639 D DG LGR + + Sbjct: 841 DLARWLPDGNIEFLGRIDNQV 861
>ACVS2_PENCH (P26046) N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine| synthase (EC 6.3.2.26) (Delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase) (ACV synthetase) (ACVS) Length = 3791 Score = 43.1 bits (100), Expect = 7e-04 Identities = 40/126 (31%), Positives = 55/126 (43%), Gaps = 19/126 (15%) Frame = +1 Query: 319 HRLLERYGMTE--FVMALS--NPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGV-GEL 483 +R+L YG TE FV AL +P RK+ ++G+P+ V+ I+ G GEL Sbjct: 614 NRILNEYGFTESAFVTALKIFDP-ESTRKDTSLGRPVRNVKCYILNPSLKRVPIGATGEL 672 Query: 484 CIKSPSLFKEYWKRPEVTAESFIDGGF--------------FKTGDTVTVDEDGYFIILG 621 I + K Y RPE+T FI F +KTGD +G LG Sbjct: 673 HIGGLGISKGYLNRPELTPHRFIPNPFQTDCEKQLGINSLMYKTGDLARWLPNGEVEYLG 732 Query: 622 RTNADI 639 R + I Sbjct: 733 RADFQI 738 Score = 40.4 bits (93), Expect = 0.005 Identities = 34/131 (25%), Positives = 54/131 (41%), Gaps = 18/131 (13%) Frame = +1 Query: 247 LRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEFVMALSN---PLHGARKEGTVGKPL 417 LR + C A P+ + E ++ YG TE + P R + ++G+ + Sbjct: 1680 LRRVDCVGEAFSEPVFDKIRETFHGLVINGYGPTEVSITTHKRLYPFPERRMDKSIGQQV 1739 Query: 418 PRVEAKIIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESFIDGGF---------- 564 + ++ +D T G VGEL + + + Y R +VTAE FI F Sbjct: 1740 HNSTSYVLNEDMKRTPIGAVGELYLGGEGVVRGYHNRADVTAERFIPNPFQSEEDKREGR 1799 Query: 565 ----FKTGDTV 585 +KTGD V Sbjct: 1800 NSRLYKTGDLV 1810
>ACSA_STRCO (Q9X928) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 651 Score = 43.1 bits (100), Expect = 7e-04 Identities = 30/114 (26%), Positives = 56/114 (49%), Gaps = 8/114 (7%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKS- 495 +++ + TE + PL G K G+ +PLP + A ++ D+ E +G G + + Sbjct: 410 VVDTWWQTETGAMMITPLPGVTHAKPGSAQRPLPGISATVVDDEANEVPNGGGGYLVLTE 469 Query: 496 --PSLFKEYWKRPEVTAESF---IDGGFFKTGDTVTVDEDGYFIILGRTNADIM 642 PS+ + W + +++ +G +F GD D+DG +LGR + D+M Sbjct: 470 PWPSMLRTIWGDDQRFIDTYWSRFEGKYF-AGDGAKKDDDGDIWLLGRVD-DVM 521
>ACS1_CANGA (Q6FLU2) Acetyl-coenzyme A synthetase 1 (EC 6.2.1.1) (Acetate--CoA| ligase 1) (Acyl-activating enzyme 1) Length = 704 Score = 43.1 bits (100), Expect = 7e-04 Identities = 36/113 (31%), Positives = 54/113 (47%), Gaps = 11/113 (9%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLHGA---RKEGTVGKPLPRVEAKIIMDD--GTETKDGVGE--L 483 +++ Y TE L PL G K G+ P +E +I+D G E D E L Sbjct: 456 IVDTYWQTESGSHLVTPLAGGVTPMKPGSASLPFFGIET-VILDPTTGEEINDSHAEGVL 514 Query: 484 CIKSP--SLFKEYWKRPEVTAESFIDG--GFFKTGDTVTVDEDGYFIILGRTN 630 IK P S + WK + +++++ G++ TGD D+DGY ILGR + Sbjct: 515 AIKRPWPSFARTIWKNHDRFLDTYLNPYKGYYFTGDGAARDKDGYIWILGRVD 567
>ACVS1_PENCH (P19787) N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine| synthase (EC 6.3.2.26) (Delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase) (ACV synthetase) (ACVS) Length = 3746 Score = 43.1 bits (100), Expect = 7e-04 Identities = 40/126 (31%), Positives = 55/126 (43%), Gaps = 19/126 (15%) Frame = +1 Query: 319 HRLLERYGMTE--FVMALS--NPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGV-GEL 483 +R+L YG TE FV AL +P RK+ ++G+P+ V+ I+ G GEL Sbjct: 584 NRILNEYGFTESAFVTALKIFDP-ESTRKDTSLGRPVRNVKCYILNPSLKRVPIGATGEL 642 Query: 484 CIKSPSLFKEYWKRPEVTAESFIDGGF--------------FKTGDTVTVDEDGYFIILG 621 I + K Y RPE+T FI F +KTGD +G LG Sbjct: 643 HIGGLGISKGYLNRPELTPHRFIPNPFQTDCEKQLGINSLMYKTGDLARWLPNGEVEYLG 702 Query: 622 RTNADI 639 R + I Sbjct: 703 RADFQI 708 Score = 40.4 bits (93), Expect = 0.005 Identities = 34/131 (25%), Positives = 54/131 (41%), Gaps = 18/131 (13%) Frame = +1 Query: 247 LRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEFVMALSN---PLHGARKEGTVGKPL 417 LR + C A P+ + E ++ YG TE + P R + ++G+ + Sbjct: 1648 LRRVDCVGEAFSEPVFDKIRETFHGLVINGYGPTEVSITTHKRLYPFPERRMDKSIGQQV 1707 Query: 418 PRVEAKIIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESFIDGGF---------- 564 + ++ +D T G VGEL + + + Y R +VTAE FI F Sbjct: 1708 HNSTSYVLNEDMKRTPIGSVGELYLGGEGVVRGYHNRADVTAERFIPNPFQSEEDKREGR 1767 Query: 565 ----FKTGDTV 585 +KTGD V Sbjct: 1768 NSRLYKTGDLV 1778
>ACSA_METSO (P27095) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 672 Score = 42.4 bits (98), Expect = 0.001 Identities = 49/181 (27%), Positives = 75/181 (41%), Gaps = 17/181 (9%) Frame = +1 Query: 133 DEAITVFTGVPTVYTRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALP-SPLMKRWEE 309 D +TV PT R+ + PD+ Y LRL+ GS P +P W Sbjct: 372 DHKVTVLYTAPTA-VRMFMKQGAEWPDK-----YDLSSLRLL--GSVGEPINPEAWMWYR 423 Query: 310 VTCHR----LLERYGMTEFVMALSNPLH-GARKEGTVGKPLPRVEAKIIMDDGTETKDGV 474 R +++ + TE L++PL K G+ PLP + I+ ++G E G Sbjct: 424 EHIGRGELQIMDTWWQTETGTFLNSPLPITPLKPGSCTFPLPGYDISILDEEGNEVPLGS 483 Query: 475 GELCIKS---PSLFKEYWKRPEVTAESF------IDG--GFFKTGDTVTVDEDGYFIILG 621 G + PS+ + +W E + + + G G + GD D+DGYF I G Sbjct: 484 GGNIVALKPYPSMLRAFWGDKERFMKEYWQFYWDVPGRRGVYLAGDKAQRDKDGYFFIQG 543 Query: 622 R 624 R Sbjct: 544 R 544
>SRFAC_BACSU (Q08787) Surfactin synthetase subunit 3| Length = 1274 Score = 42.4 bits (98), Expect = 0.001 Identities = 39/145 (26%), Positives = 63/145 (43%), Gaps = 12/145 (8%) Frame = +1 Query: 241 KQLRLMMCGSSALPSPLMKRWEEVTCH-RLLERYGMTE-FVMALSNPLHGARKEGT---V 405 K LR ++ G P +++ + +L+ YG TE V A ++ +H + + Sbjct: 720 KGLRCILFGGERASVPHVRKALRIMGPGKLINCYGPTEGTVFATAHVVHDLPDSISSLPI 779 Query: 406 GKPLPRVEAKIIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESFIDGGF------ 564 GKP+ I+ + G VGELCI + K Y R ++T E FI+ F Sbjct: 780 GKPISNASVYILNEQSQLQPFGAVGELCISGMGVSKGYVNRADLTKEKFIENPFKPGETL 839 Query: 565 FKTGDTVTVDEDGYFIILGRTNADI 639 ++TGD DG GR + + Sbjct: 840 YRTGDLARWLPDGTIEYAGRIDDQV 864
>DLTA_LACPL (Q88VM6) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 508 Score = 42.0 bits (97), Expect = 0.002 Identities = 56/226 (24%), Positives = 93/226 (41%), Gaps = 18/226 (7%) Frame = +1 Query: 16 NALFAPLYSG--SVVEFMPKFSVRGVWQRWCESYPKGTSKNDEAITVFTGVPTVYTRLLQ 189 N+L P YS SV++ P ++ G + PK + D+ +F +PT+ + Sbjct: 188 NSLSQPPYSFDLSVMDVYPTLALGGTLY----ALPKAVT--DDFKQLFAALPTLPINVWV 241 Query: 190 GYDSMNPDQQSACSYAAKQL----RLMMCGSSAL---PSPLMKRWEEVTCHRLLERYGMT 348 S + A+ L + CG + L KR+ + R+ YG T Sbjct: 242 STPSFMDICLLEPKFNAENLPTLTHFLFCGEELTHKTAATLKKRFPDA---RIFNTYGPT 298 Query: 349 EFVMA-----LSNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFK 510 E +A +++ +G ++ ++G +G GEL I PS+ K Sbjct: 299 ETCVAVTQIEITDAALAQYDRLPIGYAKADTRILVVDENGEAVPNGTEGELIIAGPSVSK 358 Query: 511 EYWKRPEVTAESF--IDG-GFFKTGDTVTVDEDGYFIILGRTNADI 639 Y E TA++F +DG + +GD T+D DG F GR + I Sbjct: 359 GYLNNSEKTAKAFFELDGQPAYHSGDIGTMDADGLFRYRGRVDFQI 404
>SID2_USTMA (O43103) Ferrichrome siderophore peptide synthetase (EC 6.-.-.-)| Length = 3947 Score = 42.0 bits (97), Expect = 0.002 Identities = 38/140 (27%), Positives = 60/140 (42%), Gaps = 9/140 (6%) Frame = +1 Query: 244 QLRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEFVMALSNPLHGARKEGT---VGKP 414 +L +M G + S ++ W L+ +G TE + N L ++ T +G Sbjct: 2744 RLEWLMSGGDVIDSRVVDEWNHAK-RLLINAWGPTE--ATIGNTLGQVKRGATRNLIGGV 2800 Query: 415 LPRVEAKIIMDDGTET--KDGVGELCIKSPSLFKEYWKRPEVTAESFI---DG-GFFKTG 576 P ++ ++ T +GEL + P L Y+ R E+TAE FI DG ++TG Sbjct: 2801 YPSSSMFVLDENSTRILPSGAIGELAVGGPQLADCYYGREELTAEKFILLEDGTRVYRTG 2860 Query: 577 DTVTVDEDGYFIILGRTNAD 636 D D LGR +D Sbjct: 2861 DLGRFLVDDTVECLGRIGSD 2880
>ACS2_ASHGO (Q750T7) Acetyl-coenzyme A synthetase 2 (EC 6.2.1.1) (Acetate--CoA| ligase 2) (Acyl-activating enzyme 2) Length = 687 Score = 41.6 bits (96), Expect = 0.002 Identities = 36/104 (34%), Positives = 48/104 (46%), Gaps = 9/104 (8%) Frame = +1 Query: 346 TEFVMALSNPLHGA--RKEGTVGKPLPRVEAKII---MDDGTETKDGVGELCIKSP--SL 504 TE L PL GA K G+ P + A II D E D G L IKSP S+ Sbjct: 430 TESGSHLIAPLAGAIPTKPGSATVPFFGINACIIDPVTGDELEGNDVEGVLAIKSPWPSM 489 Query: 505 FKEYWKRPEVTAESFIDG--GFFKTGDTVTVDEDGYFIILGRTN 630 + W + E+++ G++ TGD D DGY+ I GR + Sbjct: 490 ARSVWNNHDRYIETYLKPYPGYYFTGDGAGRDHDGYYWIRGRVD 533
>ACSA_DEIRA (Q9RRL7) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 649 Score = 41.6 bits (96), Expect = 0.002 Identities = 53/215 (24%), Positives = 88/215 (40%), Gaps = 11/215 (5%) Frame = +1 Query: 19 ALFAPLYSGSVVEFMPKFSVRGVWQRWCESYPKGTSKNDEAITVFTGVPTVYTRLLQGYD 198 +++ PL +G+ V + W R+ + K +T+ PT +Q D Sbjct: 322 SVYGPLLNGATVVMYEGAPNQPDWGRFWDIVQK------HRVTILYTAPTAIRSFMQHGD 375 Query: 199 SMNPDQQSACSYAAKQLRLM-MCGSSALPSPLMKRWEEVTCHR--LLERYGMTEFVMALS 369 + P + Y LRL+ G P M + + R +++ + TE + Sbjct: 376 EI-PGR-----YDLASLRLLGSVGEPINPEAWMWYYRVIGGERCPVVDTWWQTETGSIML 429 Query: 370 NPLHGA--RKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKS---PSLFKEYWKRPEV 534 L GA K G+ G P+ VE ++ DG E D G L + PS+ + + E Sbjct: 430 TTLPGAFPSKPGSAGLPMFGVEPALMTRDGEEIGDDDGGLLVIKRPWPSMLRTVYGDDER 489 Query: 535 TAESF---IDGGFFKTGDTVTVDEDGYFIILGRTN 630 +S+ I +F GD D DGY+ I+GR + Sbjct: 490 YRKSYWGEIPHVYF-AGDGARRDHDGYYTIVGRVD 523
>ACSA2_PSEAE (Q9HV66) Acetyl-coenzyme A synthetase 2 (EC 6.2.1.1) (Acetate--CoA| ligase 2) (Acyl-activating enzyme 2) Length = 645 Score = 41.6 bits (96), Expect = 0.002 Identities = 50/176 (28%), Positives = 81/176 (46%), Gaps = 13/176 (7%) Frame = +1 Query: 142 ITVFTGVPTVYTRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALP-SPLMKRWE---- 306 + +F PT L++ D+ P +Q++ S LRL+ GS P +P W Sbjct: 348 VNIFYTAPTAIRALMREGDA--PVRQTSRS----SLRLL--GSVGEPINPEAWEWYYQVV 399 Query: 307 -EVTCHRLLERYGMTEFVMALSNPLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKD-GV 474 E C +L+ + TE L PL GA K G+ +P V+ ++ + G E G Sbjct: 400 GEKRCP-ILDTWWQTETGSILITPLPGATALKPGSATRPFFGVQPVLLDEKGKEIDGAGS 458 Query: 475 GELCIKS--PSLFKEYWKRPEVTAESFIDG--GFFKTGDTVTVDEDGYFIILGRTN 630 G L IK+ PS + + + +++ G++ +GD DEDGY+ I GR + Sbjct: 459 GVLAIKASWPSQIRSVYGDHQRMIDTYFKPYPGYYFSGDGARRDEDGYYWITGRVD 514
>ACS1_KLULA (O60011) Acetyl-coenzyme A synthetase 1 (EC 6.2.1.1) (Acetate--CoA| ligase 1) (Acyl-activating enzyme 1) Length = 707 Score = 41.2 bits (95), Expect = 0.003 Identities = 45/178 (25%), Positives = 74/178 (41%), Gaps = 15/178 (8%) Frame = +1 Query: 142 ITVFTGVPTVYTRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCH 321 +T F PT L + DS ++ K LR + + + + + + E Sbjct: 401 VTQFYVAPTALRLLKRAGDSFTE------GFSLKSLRSLGSVGEPIAAEVWEWYSEKIGK 454 Query: 322 R---LLERYGMTEFVMALSNPLHGAR---KEGTVGKPLPRVEAKIIMDDGTETKDGVGE- 480 +++ Y TE L PL G K G P ++ ++ D T + GE Sbjct: 455 NELPIVDTYWQTESGSHLVTPLAGGATPMKPGAAAFPFFGIDLAVL--DPTTGIEQTGEH 512 Query: 481 ----LCIKSP--SLFKEYWKRPEVTAESFIDG--GFFKTGDTVTVDEDGYFIILGRTN 630 L IK P S + WK + ++++ G++ TGD V D+DG+F ILGR + Sbjct: 513 AEGVLAIKRPWPSFARTIWKNNDRFLDTYLKPYPGYYFTGDGVARDKDGFFWILGRVD 570
>BAIB_EUBSP (P19409) Bile acid-coenzyme A ligase (EC 6.-.-.-)| Length = 520 Score = 41.2 bits (95), Expect = 0.003 Identities = 36/130 (27%), Positives = 62/130 (47%), Gaps = 8/130 (6%) Frame = +1 Query: 259 MCGSSALPSPLMKR-WEEVTC-HRLLERYGMTEFV-MALSNPLHGARKEGTVGKPLPRVE 429 +C + + SP +K+ W ++ ++ E Y MTE + + + G++G+P+ + Sbjct: 292 LCHTGGVCSPWLKQIWIDLLGPEKIYEMYSMTECIGLTCIRGDEWVKHPGSIGRPVGDSK 351 Query: 430 AKIIMDDGTETKD-GVGELCIKSPS--LFKEY--WKRPEVTAESFIDGGFFKTGDTVTVD 594 I ++G E +GE+ + +P+ L EY W+ EV +GGF GD VD Sbjct: 352 VSIRDENGKEVAPFEIGEIYMTAPASYLVTEYINWEPLEVK-----EGGFRSVGDIGYVD 406 Query: 595 EDGYFIILGR 624 E GY R Sbjct: 407 EQGYLYFSDR 416
>ACS2_CANAL (Q8NJN3) Acetyl-coenzyme A synthetase 2 (EC 6.2.1.1) (Acetate--CoA| ligase 2) (Acyl-activating enzyme 2) (Fragment) Length = 581 Score = 40.8 bits (94), Expect = 0.003 Identities = 46/155 (29%), Positives = 67/155 (43%), Gaps = 16/155 (10%) Frame = +1 Query: 214 QQSACSYAAKQLRLMMCGSSALP-SPLMKRWEEV-----TCHRLLERYGMTEFVMALSNP 375 +Q Y LR + GS P SP + W CH + + Y TE L P Sbjct: 384 EQEIVKYDLSSLRTL--GSVGEPISPDIWEWYNEFVGKNQCH-ISDTYWQTESGSHLIAP 440 Query: 376 LHGA--RKEGTVGKPLPRVEAKIIMDDGT----ETKDGVGELCIKS--PSLFKEYWKRPE 531 L G K G+ P ++A +I D T E D G L IK PS+ + +K Sbjct: 441 LAGVVPNKPGSASYPFFGIDAALI-DPVTGVEIEGNDAEGVLAIKDHWPSMARTVYKNHT 499 Query: 532 VTAESFIDG--GFFKTGDTVTVDEDGYFIILGRTN 630 +++++ G++ TGD D DGY+ I GR + Sbjct: 500 KYMDTYMNPYPGYYFTGDGAARDHDGYYWIRGRVD 534
>ACSA_SYNY3 (Q55404) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 653 Score = 40.4 bits (93), Expect = 0.005 Identities = 33/118 (27%), Positives = 55/118 (46%), Gaps = 16/118 (13%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLHGA--RKEGTVGKPLPRVEAKIIMDDGTETK-DGVGELCIKS 495 +++ + TE + PL GA K G+ KP P + A+I+ DG + D G L IK Sbjct: 414 IVDTWWQTETGGIMLTPLPGAIPTKPGSCTKPFPGIVAEIVDLDGNPVESDQGGFLVIKQ 473 Query: 496 P--SLFKE-----------YWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTN 630 P S+ ++ YW+ + ++ + GD D+DGYF ++GR + Sbjct: 474 PWPSMIRDVYGDTDRFRHTYWEHIQPKEGQYL----YFAGDGARRDKDGYFWVMGRVD 527
>PPS3_BACSU (P39847) Peptide synthetase 3| Length = 2555 Score = 40.4 bits (93), Expect = 0.005 Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 7/86 (8%) Frame = +1 Query: 403 VGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF----- 564 +GKP+P ++ GV GEL I + + Y RP +T E F++ F Sbjct: 782 IGKPVPGARLYVLDPHLAVQPSGVAGELYIAGAGVARGYLNRPALTEERFLEDPFYLGER 841 Query: 565 -FKTGDTVTVDEDGYFIILGRTNADI 639 +KTGD DG LGRT+ + Sbjct: 842 MYKTGDVARWLPDGNVEFLGRTDDQV 867 Score = 38.5 bits (88), Expect = 0.017 Identities = 39/143 (27%), Positives = 60/143 (41%), Gaps = 11/143 (7%) Frame = +1 Query: 244 QLRLMMCGSSALPSPLMKRWEEVTCH-RLLERYGMTEFVMALSNPLHGARKEGT---VGK 411 QL+ ++ G AL + R V + YG TE S LH + +G+ Sbjct: 1759 QLKHLIIGGEALSPSHVNRIRNVCPEVSIWNGYGPTENT-TFSTCLHIQKTYELSIPIGR 1817 Query: 412 PLPRVEAKIIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESFIDGGF------FK 570 P+ A I+ G G VGELC+ + + Y RP++T E F+ F ++ Sbjct: 1818 PVGNSTAFILNQWGVLQPVGAVGELCVGGDGVARGYLGRPDLTKEKFVPHPFAPGDRLYR 1877 Query: 571 TGDTVTVDEDGYFIILGRTNADI 639 TGD DG +GR + + Sbjct: 1878 TGDLARWLSDGTIEYVGRIDDQV 1900
>DLTA_STRMU (Q53526) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 516 Score = 40.4 bits (93), Expect = 0.005 Identities = 32/115 (27%), Positives = 54/115 (46%), Gaps = 9/115 (7%) Frame = +1 Query: 322 RLLERYGMTEFVMALS-----NPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGV-GEL 483 R++ YG TE +ALS + + K +G P II + G + +G GE+ Sbjct: 295 RIVNAYGPTEATVALSALAVTDKMLETCKRLPIGYTKPDSPTFIIDESGHKLANGQQGEI 354 Query: 484 CIKSPSLFKEYWKRPEVTAESFIDG---GFFKTGDTVTVDEDGYFIILGRTNADI 639 + P++ K Y PE TA +F + + TGD ++ ++G + GR + I Sbjct: 355 IVSGPAVSKGYLNNPERTAAAFFEFEGLPAYHTGDLGSMTDEGLLLYGGRMDFQI 409
>ACVS_CEPAC (P25464) N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase| (EC 6.3.2.26) (Delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase) (ACV synthetase) (ACVS) Length = 3712 Score = 40.4 bits (93), Expect = 0.005 Identities = 38/153 (24%), Positives = 60/153 (39%), Gaps = 22/153 (14%) Frame = +1 Query: 247 LRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEFVMALSN---PLHGARKEGTVGKPL 417 LR + C A P+ + E ++ YG TE + P R + ++G L Sbjct: 1622 LRRVDCVGEAFSEPVFDKIRETFPGLIINGYGPTEVSITTHKRPYPFPERRTDKSIGCQL 1681 Query: 418 PRVEAKIIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESFIDGGF---------- 564 + ++ DD G VGEL + + + Y RP++TA+ F F Sbjct: 1682 DNSTSYVLNDDMKRVPIGAVGELYLGGDGVARGYHNRPDLTADRFPANPFQTEQERLEGR 1741 Query: 565 ----FKTGDTV----TVDEDGYFIILGRTNADI 639 +KTGD V + DG LGR + + Sbjct: 1742 NARLYKTGDLVRWIHNANGDGEIEYLGRNDFQV 1774
>PPS1_BACSU (P39845) Peptide synthetase 1| Length = 2561 Score = 40.4 bits (93), Expect = 0.005 Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 7/86 (8%) Frame = +1 Query: 403 VGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF----- 564 +GKP+P ++ GV GEL I + + Y RP +T E F++ F Sbjct: 776 IGKPVPGARLYVLDPHLAVQPSGVAGELYIAGAGVARGYLNRPALTEERFLEDPFYPGER 835 Query: 565 -FKTGDTVTVDEDGYFIILGRTNADI 639 +KTGD DG LGRT+ + Sbjct: 836 MYKTGDVARWLPDGNVEFLGRTDDQV 861
>DLTA_STRA5 (P59591) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 511 Score = 40.0 bits (92), Expect = 0.006 Identities = 32/115 (27%), Positives = 54/115 (46%), Gaps = 9/115 (7%) Frame = +1 Query: 322 RLLERYGMTEFVMALS-----NPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGV-GEL 483 R++ YG TE +ALS + + K +G +I ++G + +G GE+ Sbjct: 291 RIVNAYGPTEATVALSAVAITDEMLETCKRLPIGYTKDDSPTYVIDEEGHKLPNGEQGEI 350 Query: 484 CIKSPSLFKEYWKRPEVTAESFIDG---GFFKTGDTVTVDEDGYFIILGRTNADI 639 I P++ K Y PE TAE+F + TGD ++ ++G + GR + I Sbjct: 351 IIAGPAVSKGYLNNPEKTAEAFFQFEGLPAYHTGDLGSMTDEGLLLYGGRMDFQI 405
>DLTA_STRA3 (Q8VM67) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 511 Score = 40.0 bits (92), Expect = 0.006 Identities = 32/115 (27%), Positives = 54/115 (46%), Gaps = 9/115 (7%) Frame = +1 Query: 322 RLLERYGMTEFVMALS-----NPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGV-GEL 483 R++ YG TE +ALS + + K +G +I ++G + +G GE+ Sbjct: 291 RIVNAYGPTEATVALSAVAITDEMLETCKRLPIGYTKDDSPTYVIDEEGHKLPNGEQGEI 350 Query: 484 CIKSPSLFKEYWKRPEVTAESFIDG---GFFKTGDTVTVDEDGYFIILGRTNADI 639 I P++ K Y PE TAE+F + TGD ++ ++G + GR + I Sbjct: 351 IIAGPAVSKGYLNNPEKTAEAFFQFEGLPAYHTGDLGSMTDEGLLLYGGRMDFQI 405
>ACVS_EMENI (P27742) N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine| synthase (EC 6.3.2.26) (Delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase) (ACV synthetase) (ACVS) Length = 3770 Score = 39.7 bits (91), Expect = 0.008 Identities = 38/123 (30%), Positives = 53/123 (43%), Gaps = 18/123 (14%) Frame = +1 Query: 325 LLERYGMTE--FVMALSNPLHG-ARKEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIK 492 +L YG TE FV AL+ G AR ++G+P+ V+ I+ G GEL I Sbjct: 613 ILNEYGFTESAFVTALNVFEPGSARNNTSLGRPVRNVKCYILNKSLKRVPIGATGELHIG 672 Query: 493 SPSLFKEYWKRPEVTAESFIDGGF--------------FKTGDTVTVDEDGYFIILGRTN 630 + K Y RP++T + FI F +KTGD +G LGR + Sbjct: 673 GLGISKGYLNRPDLTPQRFIPNPFQTDHEKELGLNQLMYKTGDLARWLPNGEIEYLGRAD 732 Query: 631 ADI 639 I Sbjct: 733 FQI 735 Score = 38.5 bits (88), Expect = 0.017 Identities = 36/151 (23%), Positives = 60/151 (39%), Gaps = 20/151 (13%) Frame = +1 Query: 247 LRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEFVMALSN---PLHGARKEGTVGKPL 417 LR + C A P+ + + ++ YG TE + P R + ++G+ + Sbjct: 1674 LRRVDCVGEAFSQPVFDQIRDTFQGLIINGYGPTEISITTHKRLYPFPERRTDKSIGQQI 1733 Query: 418 PRVEAKIIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESFIDGGF---------- 564 + ++ D G VGEL + + + Y RPEVTAE F+ F Sbjct: 1734 GNSTSYVLNADMKRVPIGAVGELYLGGEGVARGYHNRPEVTAERFLRNPFQTDSERQNGR 1793 Query: 565 ----FKTGDTV--TVDEDGYFIILGRTNADI 639 ++TGD V +G LGR + + Sbjct: 1794 NSRLYRTGDLVRWIPGSNGEIEYLGRNDFQV 1824
>ACS2_KLULA (Q9Y7B5) Acetyl-coenzyme A synthetase 2 (EC 6.2.1.1) (Acetate--CoA| ligase 2) (Acyl-activating enzyme 2) Length = 684 Score = 39.3 bits (90), Expect = 0.010 Identities = 63/221 (28%), Positives = 92/221 (41%), Gaps = 17/221 (7%) Frame = +1 Query: 19 ALFAPLYSGS---VVEFMPKFSVRGVWQRWCESYPKGTSKNDEAITVFTGVPTVYTRLLQ 189 AL+ PL G+ + E P + G + R E + T F PT RL++ Sbjct: 331 ALYGPLTLGTATIIFESTPAYPDYGRYWRIIERH---------RATHFYVAPTAL-RLIK 380 Query: 190 GYDSMNPDQQSACSYAAKQLRLMMCGSSALP-SPLMKRW--EEVTCHR--LLERYGMTEF 354 ++ Y LR++ GS P SP + W E+V + + + TE Sbjct: 381 -----RVGEEEIAKYDTSSLRVL--GSVGEPISPDLWEWYHEKVGKNNCVICDTMWQTES 433 Query: 355 VMALSNPLHGA--RKEGTVGKPLPRVEAKIIMD-DGTETK--DGVGELCIKSP--SLFKE 513 L PL GA K G+ P + A II G E K D G L +KSP S+ + Sbjct: 434 GSHLIAPLAGAVPTKPGSATVPFFGINACIIDPVSGEELKGNDVEGVLAVKSPWPSMARS 493 Query: 514 YWKRPEVTAESFIDG--GFFKTGDTVTVDEDGYFIILGRTN 630 W E+++ G++ TGD D DGY+ I GR + Sbjct: 494 VWNNHARYFETYLKPYPGYYFTGDGAGRDHDGYYWIRGRVD 534
>DLTA_BACSU (P39581) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 503 Score = 39.3 bits (90), Expect = 0.010 Identities = 36/137 (26%), Positives = 61/137 (44%), Gaps = 9/137 (6%) Frame = +1 Query: 256 MMCGSSALPSPLMKRWEEVTCHRLLERYGMTEFVMA-----LSNPLHGARKEGTVGKPLP 420 M CG S E ++ YG TE +A ++N + + VG P Sbjct: 266 MFCGEVLPVSVAKALLERFPKAKIFNTYGPTEATVAVTSVEITNDVISRSESLPVGFAKP 325 Query: 421 RVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFI--DGGF-FKTGDTVT 588 + I+ ++G +G GE+ I PS+ + Y PE+T ++F +G + ++TGD Sbjct: 326 DMNIFIMDEEGQPLPEGEKGEIVIAGPSVSRGYLGEPELTEKAFFSHEGQWAYRTGDAGF 385 Query: 589 VDEDGYFIILGRTNADI 639 + +DG GR + I Sbjct: 386 I-QDGQIFCQGRLDFQI 401
>HTS1_COCCA (Q01886) HC-toxin synthetase (EC 6.3.2.-) (HTS)| Length = 5218 Score = 38.9 bits (89), Expect = 0.013 Identities = 26/67 (38%), Positives = 33/67 (49%), Gaps = 11/67 (16%) Frame = +1 Query: 472 VGELCIKSPSLFKEYWKRPEVTAESF----IDG-------GFFKTGDTVTVDEDGYFIIL 618 VGELCI++PSL + Y PE T SF +D ++TGD V DG L Sbjct: 3317 VGELCIEAPSLARCYLANPERTEYSFPSTVLDNWQTKKGTRVYRTGDLVRYASDGTLDFL 3376 Query: 619 GRTNADI 639 GR + I Sbjct: 3377 GRKDGQI 3383 Score = 38.5 bits (88), Expect = 0.017 Identities = 24/67 (35%), Positives = 31/67 (46%), Gaps = 11/67 (16%) Frame = +1 Query: 472 VGELCIKSPSLFKEYWKRPEVTAESFI-----------DGGFFKTGDTVTVDEDGYFIIL 618 VGEL I+ L + Y PE TAE FI + +KTGD V DG I + Sbjct: 2165 VGELIIEGSILCRGYLNDPERTAEVFIRSPSWLHDLRPNSTLYKTGDLVRYSADGKIIFI 2224 Query: 619 GRTNADI 639 GR + + Sbjct: 2225 GRKDTQV 2231 Score = 36.2 bits (82), Expect = 0.085 Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 16/72 (22%) Frame = +1 Query: 472 VGELCIKSPSLFKEYWKRPEVTAESFIDG----------------GFFKTGDTVTVDEDG 603 +GEL I+S L +Y RP+ T +F+ F++TGD V +DG Sbjct: 547 IGELLIESGHLADKYLNRPDRTEAAFLSDLPWIPNYEGDSVRRGRRFYRTGDLVRYCDDG 606 Query: 604 YFIILGRTNADI 639 I +GR++ I Sbjct: 607 SLICVGRSDTQI 618
>ACSA2_RHIME (Q92KX2) Acetyl-coenzyme A synthetase 2 (EC 6.2.1.1) (Acetate--CoA| ligase 2) (Acyl-activating enzyme 2) Length = 649 Score = 38.9 bits (89), Expect = 0.013 Identities = 34/110 (30%), Positives = 52/110 (47%), Gaps = 8/110 (7%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGV--GELCIK 492 +++ + TE L PL GA K G+ +P V+ +I+ DG + DG G LCI Sbjct: 409 VVDTWWQTETGGILITPLPGATDLKPGSATRPFFGVQPQIVDSDG-KVVDGAADGNLCIT 467 Query: 493 S--PSLFKEYWKRPEVTAESFIDG--GFFKTGDTVTVDEDGYFIILGRTN 630 P + + E +++ G + TGD DEDGY+ I GR + Sbjct: 468 DSWPGQMRTVYGDHERFIQTYFSTYKGKYFTGDGCRRDEDGYYWITGRVD 517
>MENE_ECOLI (P37353) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 451 Score = 38.5 bits (88), Expect = 0.017 Identities = 48/197 (24%), Positives = 86/197 (43%), Gaps = 9/197 (4%) Frame = +1 Query: 61 MPKFSV--RGVWQRWCESYPKGTSKNDEAI-------TVFTGVPTVYTRLLQGYDSMNPD 213 +P F V +G+ RW + + T ++ + + T + VPT RLL S++ Sbjct: 182 LPLFHVSGQGIMWRWLYAGARMTVRDKQPLEQMLAGCTHASLVPTQLWRLLVNRSSVS-- 239 Query: 214 QQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEFVMALSNPLHGARK 393 L+ ++ G +A+P L ++ E R YG+TEF + A Sbjct: 240 -----------LKAVLLGGAAIPVELTEQAREQGI-RCFCGYGLTEFASTVC--AKEADG 285 Query: 394 EGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKT 573 VG PLP E KI+ + E+ +++ S+ + YW+ ++ + D G++ T Sbjct: 286 LADVGSPLPGREVKIVNN----------EVWLRAASMAEGYWRNGQLVS-LVNDEGWYAT 334 Query: 574 GDTVTVDEDGYFIILGR 624 D + +G I+GR Sbjct: 335 RDRGEM-HNGKLTIVGR 350
>ACSA_CRYPV (Q27549) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 694 Score = 38.1 bits (87), Expect = 0.022 Identities = 60/225 (26%), Positives = 93/225 (41%), Gaps = 19/225 (8%) Frame = +1 Query: 22 LFAPLYSGS---VVEFMPKFSVRGVWQRWCESYPKGTSKNDEAITVFTGVPTVYTRLLQ- 189 ++APL +G + E +P + G + E + IT F PT L + Sbjct: 353 VYAPLCNGITTLIFEGVPTYPNAGRYWEMVERH---------RITHFYAAPTAIRTLKRL 403 Query: 190 GYDSMNPDQQSACSYAAKQLRLMMCGSSALP-SPLMKRWE-----EVTCHRLLERYGMTE 351 G D + +S+ L + GS P +P RW E C +++ Y TE Sbjct: 404 GDDFVKKHDRSS---------LRVLGSVGEPINPSAWRWYHSVVGEERCS-IVDTYWQTE 453 Query: 352 FVMALSNPLHGA--RKEGTVGKPLPRVEAKIIMDDGTETKDGVGE--LCIKS--PSLFKE 513 + P+ G K G+ P +E I+ D + DG G LCIK+ P +F+ Sbjct: 454 TGGIVIAPIPGCFDTKPGSATFPFFGIEPAILDPDTGKEIDGPGSGVLCIKNSWPGMFRG 513 Query: 514 YWKRP---EVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADI 639 + E+ + F ++ TGD V D+DGY I GR + I Sbjct: 514 IFGAHYLHEIYTKPFPK--YYFTGDGVLRDQDGYLWITGRIDDTI 556
>ACSA_RHOBA (P59872) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 671 Score = 38.1 bits (87), Expect = 0.022 Identities = 30/107 (28%), Positives = 49/107 (45%), Gaps = 7/107 (6%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLHGAR--KEGTVGKPLPRVEAKIIMDDGTET-KDGVGELCIKS 495 +++ + TE + +PL G K G+ +PLP V I+ + G + G+LCI Sbjct: 437 IVDTWWQTETGGIMMSPLPGITPTKPGSCTRPLPGVVPSIVDELGNSVDSEHGGKLCISQ 496 Query: 496 P--SLFKEYWKRPEVTAESFIDG--GFFKTGDTVTVDEDGYFIILGR 624 P + + + E E + + TGD D DGY+ I+GR Sbjct: 497 PWPGMLRGIYGDEERFVEQYWSDVPDKYLTGDNARCDTDGYYWIMGR 543
>ACS1_DEBHA (Q6BQF2) Acetyl-coenzyme A synthetase 1 (EC 6.2.1.1) (Acetate--CoA| ligase 1) (Acyl-activating enzyme 1) Length = 671 Score = 37.7 bits (86), Expect = 0.029 Identities = 35/114 (30%), Positives = 55/114 (48%), Gaps = 9/114 (7%) Frame = +1 Query: 316 CHRLLERYGMTEFVMALSNPLHGAR--KEGTVGKPLPRVEAKIIMD-DGTETK--DGVGE 480 CH +++ Y TE + PL G K G+ P ++AKI+ G E K D G Sbjct: 425 CH-IVDTYWQTESGSHMLAPLAGITPTKPGSASLPCFGIDAKILDPVSGKELKENDVEGV 483 Query: 481 LCIKS--PSLFKEYWKRPEVTAESFIDG--GFFKTGDTVTVDEDGYFIILGRTN 630 LC+KS PS+ + + E+++ + +GD D DG++ ILGR + Sbjct: 484 LCVKSCWPSISRGIYNDYARFIETYLKPYPNHYFSGDGAARDVDGFYWILGRVD 537
>BACB_BACLI (O68007) Bacitracin synthetase 2 (BA2) [Includes: ATP-dependent| lysine adenylase (LysA) (Lysine activase); ATP-dependent D-ornithine adenylase (D-OrnA) (D-ornithine activase); Ornithine racemase (EC 5.1.1.12)] Length = 2607 Score = 37.4 bits (85), Expect = 0.038 Identities = 27/86 (31%), Positives = 37/86 (43%), Gaps = 7/86 (8%) Frame = +1 Query: 403 VGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFI------DGG 561 +GKPL I+ GV GEL I + + Y +PE+T E F+ G Sbjct: 1869 IGKPLDNTAFYILDPSLNPQPVGVYGELYIGGEGIARGYLNKPELTKERFVPNRFAAGGN 1928 Query: 562 FFKTGDTVTVDEDGYFIILGRTNADI 639 +KTGD DG LGR + + Sbjct: 1929 MYKTGDLARWLPDGNVEFLGRIDHQV 1954
>ACSA_BRAJA (Q89WV5) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 648 Score = 37.4 bits (85), Expect = 0.038 Identities = 50/177 (28%), Positives = 76/177 (42%), Gaps = 14/177 (7%) Frame = +1 Query: 142 ITVFTGVPTVYTRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALP-SPLMKRWE---- 306 + F PT L+QG D P ++++ + L + GS P +P W Sbjct: 348 VNTFYTAPTAIRALMQGGDE--PVKKTS------RASLRLLGSVGEPINPEAWEWYHRVV 399 Query: 307 -EVTCHRLLERYGMTEFVMALSNPLHGARK--EGTVGKPLPRVEAKIIMDDGTETK-DGV 474 E C +++ + TE L PL GA K G+ +P V +I+ DG + + Sbjct: 400 GEDRCP-IVDTWWQTETGGILITPLPGATKLKPGSATQPFFGVVPEIVDADGKVLEGETT 458 Query: 475 GELCIKS--PSLFKEYW---KRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTN 630 G LC+ P + + + R E T S G +F TGD D DGY+ I GR + Sbjct: 459 GNLCLTRAWPGMMRTVYGDHARFEQTYFSTYKGKYF-TGDGCRRDADGYYWITGRVD 514
>ACSA_SCHPO (P78773) Probable acetyl-coenzyme A synthetase (EC 6.2.1.1)| (Acetate--CoA ligase) (Acyl-activating enzyme) Length = 662 Score = 37.0 bits (84), Expect = 0.050 Identities = 29/88 (32%), Positives = 45/88 (51%), Gaps = 8/88 (9%) Frame = +1 Query: 391 KEGTVGKPLPRVEAKIIMDDGT----ETKDGVGELCIKSP--SLFKEYWKRPEVTAESFI 552 K G+ P ++A +I+D T E D G L I+SP S + W+ + ++++ Sbjct: 441 KPGSATLPFFGIDA-VIIDPLTGKIIEGNDVEGVLAIRSPWPSAARTVWRGHDRYIDTYL 499 Query: 553 DG--GFFKTGDTVTVDEDGYFIILGRTN 630 GF+ TGD T D+DGY I GR + Sbjct: 500 KPYPGFYFTGDGATRDKDGYIWIRGRVD 527
>ACVS_STRCL (Q01757) N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine| synthase (EC 6.3.2.26) (Delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase) (ACV synthetase) (ACVS) (Fragment) Length = 805 Score = 36.6 bits (83), Expect = 0.065 Identities = 35/146 (23%), Positives = 64/146 (43%), Gaps = 19/146 (13%) Frame = +1 Query: 250 RLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTE--FVMALSNPLHGA--RKEGTVGKPL 417 RL++ G L + +++ E R++ Y TE FV A+ G R + ++G+P+ Sbjct: 534 RLLLVGEE-LTAAGLRQLRERFSGRIVNEYAFTEAAFVTAVKKFAPGVTERADRSIGRPV 592 Query: 418 PRVEAKIIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESFIDGGF---------- 564 V+ ++ D G +GEL I + Y R ++TAE F+ + Sbjct: 593 RNVKWYVLSQDLKRLPVGAIGELYIGGCGVAPGYLNRDDLTAERFLTNPYASEQDRARGT 652 Query: 565 ----FKTGDTVTVDEDGYFIILGRTN 630 ++TGD + G +GR++ Sbjct: 653 NARIYRTGDLARMLPSGEVEFMGRSD 678
>ACSA_CAUCR (Q9A2I0) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 647 Score = 36.2 bits (82), Expect = 0.085 Identities = 33/110 (30%), Positives = 52/110 (47%), Gaps = 8/110 (7%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGV--GELCIK 492 +++ + TE L PL GA K G+ KPLP V+ +++ +G + DG G L I Sbjct: 408 IVDTWWQTETGGMLITPLPGATALKPGSASKPLPGVKPQLVDAEG-KFLDGATEGNLVIT 466 Query: 493 S--PSLFKEYWKRPEVTAESFIDG--GFFKTGDTVTVDEDGYFIILGRTN 630 P + + + E++ G + TGD D DGY+ I GR + Sbjct: 467 DSWPGQMRTVYGDHQRFFETYFSTYPGKYFTGDGCRRDADGYYWITGRVD 516
>ACSA_AGRT5 (Q8UBV5) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 651 Score = 36.2 bits (82), Expect = 0.085 Identities = 33/111 (29%), Positives = 56/111 (50%), Gaps = 9/111 (8%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCI-- 489 +++ + TE L +PL GA K G+ +P V+ +++ +G + G LCI Sbjct: 409 IVDTWWQTETGGILISPLPGATDLKPGSATRPFFGVQPQLVDAEGNVLEGPADGNLCIID 468 Query: 490 ----KSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTN 630 +S S++ ++ + + T S G +F TGD DEDGY+ I GR + Sbjct: 469 SWPGQSRSVYGDHQRFVD-TYFSTYKGKYF-TGDGCRRDEDGYYWITGRVD 517
>Y3568_PSEAE (P28812) Hypothetical protein PA3568| Length = 628 Score = 36.2 bits (82), Expect = 0.085 Identities = 32/152 (21%), Positives = 62/152 (40%), Gaps = 10/152 (6%) Frame = +1 Query: 205 NPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEFVMALSNPLHG 384 +P + Y LR + L S EE T + + + TE ++ P G Sbjct: 344 DPHGERVKRYDLGSLRHLFLAGEKLDSSTQHWLEEHTGRPVHDHWWQTETGWPVTAPCIG 403 Query: 385 AR----KEGTVGKPLPRVEAKIIMDDGTE---TKDGVGELCIK-SPSLFKEYWKRPEVTA 540 + G+ + +P +++ D+G + G + + P + W Sbjct: 404 IAGHDLRAGSTNRAVPGYHVQVLDDEGRPLGANRQGAIVIALPLPPGCAQTLWGDHPRYL 463 Query: 541 ESFIDG--GFFKTGDTVTVDEDGYFIILGRTN 630 ++++ G++ TGD +DEDG+ I+GRT+ Sbjct: 464 QAYLGNYPGYYHTGDGGYLDEDGFVYIMGRTD 495
>LYS2_ASHGO (Q75BB3) L-aminoadipate-semialdehyde dehydrogenase large subunit| (EC 1.2.1.31) (Alpha-aminoadipate reductase) (Alpha-AR) Length = 1385 Score = 36.2 bits (82), Expect = 0.085 Identities = 31/112 (27%), Positives = 46/112 (41%), Gaps = 8/112 (7%) Frame = +1 Query: 292 MKRWEEVTCHRLLE---RYGMTEFVMALSNP--LHGARKEGTVGKPLPRVEAKIIMDDGT 456 +K W +TC LE +Y E SNP L + G+ + V+ I+ Sbjct: 551 LKTWPLLTCTAHLEPSVQYRYFEVQSCCSNPSYLDNVKSITPAGRGMHNVQLLIVNRHDR 610 Query: 457 ETKDG---VGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDG 603 G VGE+ +++ L + Y PE+ E FID F G +D G Sbjct: 611 TKLCGIGEVGEIYVRAGGLSEGYRGLPEINKEKFIDNWFVDAGHWGGLDLSG 662
>ACSA_RHOCA (O68040) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 656 Score = 36.2 bits (82), Expect = 0.085 Identities = 31/112 (27%), Positives = 51/112 (45%), Gaps = 10/112 (8%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGV----GELC 486 +++ + TE + PL GA K G+ P V+ +++D T + G G LC Sbjct: 414 IVDTFWQTETGGHMITPLPGATPTKPGSATNPFFGVKP-VVLDPQTAVRIGEVECEGVLC 472 Query: 487 IKS--PSLFKEYWKRPEVTAESFIDG--GFFKTGDTVTVDEDGYFIILGRTN 630 I P + W + E++ G++ TGD D+DGY+ I GR + Sbjct: 473 ISDSWPGQMRTVWGDHDRFQETYFGQYRGYYFTGDGCRRDKDGYYWITGRVD 524
>ACS2_YEAST (P52910) Acetyl-coenzyme A synthetase 2 (EC 6.2.1.1) (Acetate--CoA| ligase 2) (Acyl-activating enzyme 2) Length = 683 Score = 35.8 bits (81), Expect = 0.11 Identities = 35/105 (33%), Positives = 48/105 (45%), Gaps = 10/105 (9%) Frame = +1 Query: 346 TEFVMALSNPLHGA--RKEGTVGKPLPRVEAKIIMDDGT----ETKDGVGELCIKSP--S 501 TE L PL GA K G+ P + A II D T E D G L +KSP S Sbjct: 430 TESGSHLIAPLAGAVPTKPGSATVPFFGINACII-DPVTGVELEGNDVEGVLAVKSPWPS 488 Query: 502 LFKEYWKRPEVTAESFIDG--GFFKTGDTVTVDEDGYFIILGRTN 630 + + W + ++++ G + TGD D DGY+ I GR + Sbjct: 489 MARSVWNHHDRYMDTYLKPYPGHYFTGDGAGRDHDGYYWIRGRVD 533
>ACSA_BRUSU (Q8FYQ3) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 651 Score = 35.8 bits (81), Expect = 0.11 Identities = 31/110 (28%), Positives = 53/110 (48%), Gaps = 8/110 (7%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGV--GELCIK 492 +++ + TE L PL GA K G+ +P V+ ++ ++G ++GV G LCI Sbjct: 409 IVDTWWQTENGGILITPLPGATDLKPGSATRPFFGVKPVLVDNEGN-VQEGVADGNLCIS 467 Query: 493 S--PSLFKEYWKRPEVTAESFIDG--GFFKTGDTVTVDEDGYFIILGRTN 630 P + + + E++ G + +GD DEDGY+ I GR + Sbjct: 468 DSWPGQMRTVYGDHKRFIETYFSTYKGMYFSGDGCRRDEDGYYWITGRVD 517
>ACSA_BRUME (Q8YJ48) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 651 Score = 35.8 bits (81), Expect = 0.11 Identities = 31/110 (28%), Positives = 53/110 (48%), Gaps = 8/110 (7%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGV--GELCIK 492 +++ + TE L PL GA K G+ +P V+ ++ ++G ++GV G LCI Sbjct: 409 IVDTWWQTENGGILITPLPGATDLKPGSATRPFFGVKPVLVDNEGN-VQEGVADGNLCIS 467 Query: 493 S--PSLFKEYWKRPEVTAESFIDG--GFFKTGDTVTVDEDGYFIILGRTN 630 P + + + E++ G + +GD DEDGY+ I GR + Sbjct: 468 DSWPGQMRTVYGDHKRFIETYFSTYKGMYFSGDGCRRDEDGYYWITGRVD 517
>FAD28_MYCBO (Q02278) Putative fatty-acid--CoA ligase fadD28 (EC 6.2.1.-)| (Acyl-CoA synthetase) Length = 580 Score = 35.8 bits (81), Expect = 0.11 Identities = 28/100 (28%), Positives = 45/100 (45%), Gaps = 14/100 (14%) Frame = +1 Query: 367 SNPLHGARKEGTVGKPLPRVEAKIIMDDGT--ETKDG-VGELCIKSPSLFKEYWKRPEVT 537 + P G + LPR I+D T E DG VGE+ + ++ YW++P+ + Sbjct: 362 AKPCAGGGATSLISYMLPRSPIVRIVDSDTCIECPDGTVGEIWVHGDNVANGYWQKPDES 421 Query: 538 AESF-----------IDGGFFKTGDTVTVDEDGYFIILGR 624 +F +G + +TGD+ V DG I+GR Sbjct: 422 ERTFGGKIVTPSPGTPEGPWLRTGDSGFV-TDGKMFIIGR 460
>ACSL3_MOUSE (Q9CZW4) Long-chain-fatty-acid--CoA ligase 3 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 3) (LACS 3) Length = 720 Score = 35.8 bits (81), Expect = 0.11 Identities = 35/135 (25%), Positives = 56/135 (41%), Gaps = 9/135 (6%) Frame = +1 Query: 247 LRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEFVMALSNPLHGARKEGTVGKPLPRV 426 +RL++CG + L + + C + + YG+TE A + G VG PL Sbjct: 445 IRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLTESTGAGTITEVWDYNTGRVGAPLVCC 504 Query: 427 EAKI-IMDDG----TETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDG----GFFKTGD 579 E K+ ++G T+ GE+ I ++ Y+K T F + + TGD Sbjct: 505 EIKLKNWEEGGYFNTDKPHPRGEILIGGQNVTMGYYKNEAKTKTDFFEDENGQRWLCTGD 564 Query: 580 TVTVDEDGYFIILGR 624 D DG I+ R Sbjct: 565 IGEFDPDGCLKIIDR 579
>FAD21_MYCTU (P63523) Putative fatty-acid--CoA ligase fadD21 (EC 6.2.1.-)| (Acyl-CoA synthetase) Length = 578 Score = 35.8 bits (81), Expect = 0.11 Identities = 17/59 (28%), Positives = 30/59 (50%), Gaps = 11/59 (18%) Frame = +1 Query: 472 VGELCIKSPSLFKEYWKRPEVTAESF-----------IDGGFFKTGDTVTVDEDGYFII 615 +GE+ +K ++ + YW +P+ T +F DG + +TGD + ED FI+ Sbjct: 399 IGEIWVKGDNVAEGYWNKPDETRHTFGAMLVHPSAGTPDGSWLRTGDLGFLSEDEMFIV 457
>FAD21_MYCBO (P63524) Putative fatty-acid--CoA ligase fadD21 (EC 6.2.1.-)| (Acyl-CoA synthetase) Length = 578 Score = 35.8 bits (81), Expect = 0.11 Identities = 17/59 (28%), Positives = 30/59 (50%), Gaps = 11/59 (18%) Frame = +1 Query: 472 VGELCIKSPSLFKEYWKRPEVTAESF-----------IDGGFFKTGDTVTVDEDGYFII 615 +GE+ +K ++ + YW +P+ T +F DG + +TGD + ED FI+ Sbjct: 399 IGEIWVKGDNVAEGYWNKPDETRHTFGAMLVHPSAGTPDGSWLRTGDLGFLSEDEMFIV 457
>ACS2_CANGA (Q6FXI2) Acetyl-coenzyme A synthetase 2 (EC 6.2.1.1) (Acetate--CoA| ligase 2) (Acyl-activating enzyme 2) Length = 683 Score = 35.4 bits (80), Expect = 0.15 Identities = 33/109 (30%), Positives = 51/109 (46%), Gaps = 9/109 (8%) Frame = +1 Query: 331 ERYGMTEFVMALSNPLHGA--RKEGTVGKPLPRVEAKIIMD-DGTETK--DGVGELCIKS 495 + + TE L P+ GA K G+ P ++A II G E + D G L +KS Sbjct: 426 DTFWQTESGSHLIAPMAGAIPTKPGSTTLPFFGIDACIIDPVSGVEIEGNDVEGVLAVKS 485 Query: 496 P--SLFKEYWKRPEVTAESFIDG--GFFKTGDTVTVDEDGYFIILGRTN 630 P S+ + W ++++ G++ TGD D DGY+ I GR + Sbjct: 486 PWPSMARSVWNDHVRYVDTYMKPYPGYYFTGDGAGRDHDGYYWIRGRVD 534
>S27A3_MOUSE (O88561) Long-chain fatty acid transport protein 3 (EC 6.2.1.-)| (Fatty acid transport protein 3) (FATP-3) (Solute carrier family 27 member 3) Length = 667 Score = 35.4 bits (80), Expect = 0.15 Identities = 51/224 (22%), Positives = 76/224 (33%), Gaps = 25/224 (11%) Frame = +1 Query: 43 GSVVEFMPKFSVRGVWQRWCESYPKGTSKNDEAITVFTGVPTVYTRLLQGYDSMNPDQQS 222 G+ V PKFS W C+ + +TVF Y L Y P ++ Sbjct: 330 GATVVLKPKFSASQFWDD-CQKH---------RVTVFQ-----YIGELCRYLVNQPPSKA 374 Query: 223 ACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEFVMALSN---------- 372 C + + + GS P + ++LE YGMTE +A N Sbjct: 375 ECDHKVR----LAVGSGLRPDTWERFLRRFGPLQILETYGMTEGNVATFNYTGRQGAVGR 430 Query: 373 ---------PLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKR 525 P R + G+P+ + + E V + +SP F Y Sbjct: 431 ASWLYKHIFPFSLIRYDVMTGEPIRNAQGHCMTTSPGEPGLLVAPVSQQSP--FLGYAGA 488 Query: 526 PEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNADI 639 PE+ + + F F TGD + DE G+ RT I Sbjct: 489 PELAKDKLLKDVFWSGDVFFNTGDLLVCDEQGFLHFHDRTGDTI 532
>ACS2_ZYGBA (Q96VC7) Acetyl-coenzyme A synthetase 2 (EC 6.2.1.1) (Acetate--CoA| ligase 2) (Acyl-activating enzyme 2) Length = 675 Score = 35.0 bits (79), Expect = 0.19 Identities = 34/104 (32%), Positives = 49/104 (47%), Gaps = 9/104 (8%) Frame = +1 Query: 346 TEFVMALSNPLHGA--RKEGTVGKPLPRVEAKIIMD-DGTETK--DGVGELCIKS--PSL 504 TE L P GA K G+ P V+A II G E + D G L +KS PS+ Sbjct: 430 TESGSHLIAPQAGAVPTKPGSATVPFFGVDACIIDPVTGIELQGNDVEGVLAVKSSWPSM 489 Query: 505 FKEYWKRPEVTAESFIDG--GFFKTGDTVTVDEDGYFIILGRTN 630 + W+ ++++ G++ TGD D DGY+ I GR + Sbjct: 490 ARSVWQNHHRYVDTYLKPYPGYYFTGDGAGRDHDGYYWIRGRVD 533
>ACSA_PENCH (P36333) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 669 Score = 34.7 bits (78), Expect = 0.25 Identities = 31/111 (27%), Positives = 48/111 (43%), Gaps = 9/111 (8%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLHGAR--KEGTVGKPLPRVEAKIIMDDGTET---KDGVGELCI 489 + + Y TE + PL G K G+ P +E II E D G L Sbjct: 426 ICDTYWQTETGSHVITPLGGITPTKPGSASLPFFGIEPAIIDPVSGEEIVGNDVEGVLAF 485 Query: 490 KSP--SLFKEYWKRPEVTAESFID--GGFFKTGDTVTVDEDGYFIILGRTN 630 K P S+ + W + +++++ G++ TGD D DGY+ I GR + Sbjct: 486 KQPWPSMARTVWGAHKRYMDTYLNVYKGYYFTGDGAGRDHDGYYWIRGRVD 536
>ACSA1_PSEAE (Q9I558) Acetyl-coenzyme A synthetase 1 (EC 6.2.1.1) (Acetate--CoA| ligase 1) (Acyl-activating enzyme 1) Length = 651 Score = 34.7 bits (78), Expect = 0.25 Identities = 31/111 (27%), Positives = 52/111 (46%), Gaps = 9/111 (8%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCI-- 489 +++ + TE L PL GA K G+ KP V ++ + G + G L I Sbjct: 409 IVDTWWQTETGACLMTPLPGAHAMKPGSAAKPFFGVVPALVDNLGNLIEGAAEGNLVILD 468 Query: 490 ----KSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTN 630 ++ +LF ++ + + ++F G + TGD DEDGY+ I GR + Sbjct: 469 SWPGQARTLFGDHDRFVDTYFKTF--KGMYFTGDGARRDEDGYYWITGRVD 517
>ACS2_DEBHA (Q6BS00) Acetyl-coenzyme A synthetase 2 (EC 6.2.1.1) (Acetate--CoA| ligase 2) (Acyl-activating enzyme 2) Length = 679 Score = 34.7 bits (78), Expect = 0.25 Identities = 43/154 (27%), Positives = 68/154 (44%), Gaps = 15/154 (9%) Frame = +1 Query: 214 QQSACSYAAKQLRLMMCGSSALP-SPLMKRW--EEV---TCHRLLERYGMTEFVMALSNP 375 +Q Y LR + GS P SP + W E+V CH + + Y TE P Sbjct: 384 EQEIEKYDLSSLRTL--GSVGEPISPDIWEWYNEKVGKGQCH-VTDTYWQTESGSHFIAP 440 Query: 376 LHGA--RKEGTVGKPLPRVEAKIIMD-DGTETK--DGVGELCIKS--PSLFKEYWKRPEV 534 + G K G+ P ++ +I G E + D G L +K PS+ + +K Sbjct: 441 IAGVVPNKPGSAAVPFFGIQTCLIDPVSGIEIQGNDVEGVLAVKDTWPSMARSVYKNHTK 500 Query: 535 TAESFIDG--GFFKTGDTVTVDEDGYFIILGRTN 630 +++++ G++ TGD D DGY+ I GR + Sbjct: 501 YMDTYLNPYPGYYFTGDGAARDHDGYYWIRGRVD 534
>ACSA_DROME (Q9VP61) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) (Acetyl-CoA synthetase) (ACS) (AceCS) Length = 670 Score = 34.7 bits (78), Expect = 0.25 Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 7/109 (6%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLHGAR--KEGTVGKPLPRVEAKIIMDDGTETK-DGVGELCIKS 495 +++ + TE + PL GA K G+ P V+ ++ + G E K +G G L Sbjct: 430 IVDTFWQTETGGHVITPLPGATPMKPGSASFPFFGVKPTLLDECGIEIKGEGEGYLVFSQ 489 Query: 496 P--SLFKEYWKRPEVTAESFIDG--GFFKTGDTVTVDEDGYFIILGRTN 630 P + + + E +++ G++ TGD D DGY I GR + Sbjct: 490 PWPGMMRTLYNNHERFEDTYFSKFPGYYCTGDGARRDADGYLWITGRVD 538
>ACSL3_RAT (Q63151) Long-chain-fatty-acid--CoA ligase 3 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 3) (LACS 3) (Brain acyl-CoA synthtase II) Length = 720 Score = 34.7 bits (78), Expect = 0.25 Identities = 34/135 (25%), Positives = 56/135 (41%), Gaps = 9/135 (6%) Frame = +1 Query: 247 LRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEFVMALSNPLHGARKEGTVGKPLPRV 426 +R+++CG + L + + C + + YG+TE A + G VG PL Sbjct: 445 IRVLLCGGAPLSATTQRFMNICFCCPVGQGYGLTESTGAGTITEVWDYNTGRVGAPLVCC 504 Query: 427 EAKI-IMDDG----TETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDG----GFFKTGD 579 E K+ ++G T+ GE+ I ++ Y+K T F + + TGD Sbjct: 505 EIKLKNWEEGGYFNTDKPHPRGEILIGGQNVTMGYYKNEAKTKADFFEDENGQRWLCTGD 564 Query: 580 TVTVDEDGYFIILGR 624 D DG I+ R Sbjct: 565 IGEFDPDGCLKIIDR 579
>ACSL3_HUMAN (O95573) Long-chain-fatty-acid--CoA ligase 3 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 3) (LACS 3) Length = 720 Score = 34.7 bits (78), Expect = 0.25 Identities = 35/135 (25%), Positives = 56/135 (41%), Gaps = 9/135 (6%) Frame = +1 Query: 247 LRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEFVMALSNPLHGARKEGTVGKPLPRV 426 +RL++CG + L + + C + + YG+TE A + G VG PL Sbjct: 445 IRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLTESAGAGTISEVWDYNTGRVGAPLVCC 504 Query: 427 EAKI-IMDDG----TETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDG----GFFKTGD 579 E K+ ++G T+ GE+ I S+ Y+K T F + + TGD Sbjct: 505 EIKLKNWEEGGYFNTDKPHPRGEILIGGQSVTMGYYKNEAKTKADFSEDENGQRWLCTGD 564 Query: 580 TVTVDEDGYFIILGR 624 + DG I+ R Sbjct: 565 IGEFEPDGCLKIIDR 579
>ACSA_PHYBL (Q01576) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 672 Score = 34.3 bits (77), Expect = 0.32 Identities = 29/111 (26%), Positives = 48/111 (43%), Gaps = 9/111 (8%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKD-----GVGELCI 489 +++ Y TE + +PL GA LP ++ D T K+ G L I Sbjct: 423 VVDTYWQTETGSIIVSPLPGATPTKPGSATLPFFGIDPVLLDPTTGKELTATGQTGVLAI 482 Query: 490 KSP--SLFKEYWKRPEVTAESFIDG--GFFKTGDTVTVDEDGYFIILGRTN 630 + P S+ + + E+++ G++ TGD D+DGY I GR + Sbjct: 483 RKPRPSMARSVYNNHSRFVETYLKPYPGYYFTGDGALRDDDGYIWIRGRVD 533
>FAD21_MYCLE (P54200) Putative fatty-acid--CoA ligase fadD21 (EC 6.2.1.-)| (Acyl-CoA synthetase) Length = 579 Score = 34.3 bits (77), Expect = 0.32 Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 12/85 (14%) Frame = +1 Query: 397 GTVGKPLPRVEAKIIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESF-------- 549 GT P+ R+ + D E G VGE+ + ++ + YW +PE T +F Sbjct: 377 GTPKSPIVRI---VDSDTCIECPTGRVGEIWLHGDNVAEGYWHKPEETQRTFGGKLANPS 433 Query: 550 ---IDGGFFKTGDTVTVDEDGYFII 615 +G + +TGD + ED FI+ Sbjct: 434 PGTPEGPWLRTGDLGFISEDELFIV 458
>ACSA_SYNEL (Q8DKH2) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 656 Score = 34.3 bits (77), Expect = 0.32 Identities = 53/222 (23%), Positives = 90/222 (40%), Gaps = 19/222 (8%) Frame = +1 Query: 22 LFAPLYSGSVV---EFMPKFSVRGVWQRWCESYPKGTSKNDEAITVFTGVPTVYTRLLQG 192 ++ PL +G+ E P+ S G + E Y +T+F PT ++ Sbjct: 324 VYGPLSNGATTLMYEGAPRPSNPGCFWDVIEKY---------GVTIFYTAPTA----IRA 370 Query: 193 YDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCHR--LLERYGMTEFVMAL 366 + M A ++ +L L G P M + + R +++ + TE + Sbjct: 371 FIKMGEHLPRARDLSSLRL-LGTVGEPINPEAWMWYYRVIGGERCPIVDTWWQTETGGHM 429 Query: 367 SNPLHGA--RKEGTVGKPLPRVEAKIIMDDGTETKDGVGE---LCIKSP--SLFKEYWKR 525 L GA K G+ KP P + A ++ +G GV E L I+ P + + + Sbjct: 430 ITSLPGALPMKPGSASKPFPGILADVVDLEGNPV--GVNEGGYLVIRHPWPGMMRTVYGD 487 Query: 526 PEVTAESFI------DGGFFK-TGDTVTVDEDGYFIILGRTN 630 P+ ++ DG +F GD DEDGYF ++GR + Sbjct: 488 PDRFRRTYWEHIPPRDGQYFYFAGDGARRDEDGYFWVMGRVD 529
>ACSL4_HUMAN (O60488) Long-chain-fatty-acid--CoA ligase 4 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 4) (LACS 4) Length = 711 Score = 33.9 bits (76), Expect = 0.42 Identities = 41/136 (30%), Positives = 60/136 (44%), Gaps = 10/136 (7%) Frame = +1 Query: 247 LRLMMCGSSALPSPLMKRWEEVT-CHRLLERYGMTEFVMALSNPLHGARKEGTVGKPLPR 423 +R+M+ G + L SP R+ V C + + YG+TE A + G VG PL Sbjct: 436 VRMMLSGGAPL-SPQTHRFMNVCFCCPIGQGYGLTESCGAGTVTEVTDYTTGRVGAPLIC 494 Query: 424 VEAKII--MDDGTETKDGV---GELCIKSPSLFKEYWKRPEVTAESF-IDGG---FFKTG 576 E K+ + G D GE+ I ++ Y+K E TAE + +D +F TG Sbjct: 495 CEIKLKDWQEGGYTINDKPNPRGEIVIGGQNISMGYFKNEEKTAEDYSVDENGQRWFCTG 554 Query: 577 DTVTVDEDGYFIILGR 624 D DG I+ R Sbjct: 555 DIGEFHPDGCLQIIDR 570
>ACS1_CANAL (O94049) Acetyl-coenzyme A synthetase 1 (EC 6.2.1.1) (Acetate--CoA| ligase 1) (Acyl-activating enzyme 1) Length = 675 Score = 33.9 bits (76), Expect = 0.42 Identities = 32/111 (28%), Positives = 51/111 (45%), Gaps = 9/111 (8%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLHGAR--KEGTVGKPLPRVEAKII-MDDGTETKDG--VGELCI 489 +++ Y TE L PL G K G+ P V+ KI+ G E D G L I Sbjct: 429 IVDTYWQTESGSHLLTPLAGITPTKPGSASLPFFGVDPKILDPTTGEELPDNDVEGVLAI 488 Query: 490 KS--PSLFKEYWKRPEVTAESFID--GGFFKTGDTVTVDEDGYFIILGRTN 630 KS PS+ + + ++++ ++ +GD D DG++ ILGR + Sbjct: 489 KSAWPSITRGIYNDYNRFIDTYLAPYANYYFSGDGAARDRDGFYWILGRVD 539
>ACSL4_RAT (O35547) Long-chain-fatty-acid--CoA ligase 4 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 4) (LACS 4) Length = 670 Score = 33.9 bits (76), Expect = 0.42 Identities = 41/136 (30%), Positives = 60/136 (44%), Gaps = 10/136 (7%) Frame = +1 Query: 247 LRLMMCGSSALPSPLMKRWEEVT-CHRLLERYGMTEFVMALSNPLHGARKEGTVGKPLPR 423 +R+M+ G + L SP R+ V C + + YG+TE A + G VG PL Sbjct: 395 VRMMLSGGAPL-SPQTHRFMNVCFCCPIGQGYGLTESCGAGTVTEVTDYTTGRVGAPLIC 453 Query: 424 VEAKII--MDDGTETKDGV---GELCIKSPSLFKEYWKRPEVTAESF-IDGG---FFKTG 576 E K+ + G D GE+ I ++ Y+K E TAE + +D +F TG Sbjct: 454 CEIKLKDWQEGGYTVHDKPNPRGEIVIGGQNISMGYFKNEEKTAEDYSVDENGQRWFCTG 513 Query: 577 DTVTVDEDGYFIILGR 624 D DG I+ R Sbjct: 514 DIGEFHPDGCLQIIDR 529
>DLTA_LISMF (Q721J2) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 510 Score = 33.9 bits (76), Expect = 0.42 Identities = 37/144 (25%), Positives = 64/144 (44%), Gaps = 13/144 (9%) Frame = +1 Query: 247 LRLMMCG---SSALPSPLMKRWEEVTCHRLLERYGMTEFVMALSN-----PLHGARKEGT 402 +R + CG + S L+ R+ + + YG TE +A++ + A Sbjct: 269 IRFLFCGEVLAKKTASELLNRFPDAVIYNT---YGPTEATVAVTQVKVTREVIDAYPSLP 325 Query: 403 VGKPLPRVEAKII-MDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFID-GGF--F 567 +G P + I+ + G +G GE+ + S+ K Y PE T + F D G+ + Sbjct: 326 LGVIKPDMRLHIVDQETGEVLPEGEKGEIVLIGASVSKGYLNEPEKTDQVFFDYKGYQAY 385 Query: 568 KTGDTVTVDEDGYFIILGRTNADI 639 +TGD+ + +DGY GR + I Sbjct: 386 RTGDSGII-KDGYLFFQGRLDFQI 408
>ACSA_VIBVY (Q7MGU3) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 650 Score = 33.9 bits (76), Expect = 0.42 Identities = 32/111 (28%), Positives = 50/111 (45%), Gaps = 9/111 (8%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGVGE----LC 486 +++ + TE L PL GA K G+ +P V+ ++ + G +D E + Sbjct: 409 IVDTWWQTETGGILITPLPGATALKPGSATRPFFGVQPALVDNMGNVIEDQAAEGNLVIL 468 Query: 487 IKSPSLFKEYW---KRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTN 630 P + + +R E T S G +F TGD DEDGY+ I GR + Sbjct: 469 DSWPGQMRTVYGDHERFEQTYFSTFKGMYF-TGDGARRDEDGYYWITGRVD 518
>ACSA_VIBVU (Q8DCZ9) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 650 Score = 33.9 bits (76), Expect = 0.42 Identities = 32/111 (28%), Positives = 50/111 (45%), Gaps = 9/111 (8%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGVGE----LC 486 +++ + TE L PL GA K G+ +P V+ ++ + G +D E + Sbjct: 409 IVDTWWQTETGGILITPLPGATALKPGSATRPFFGVQPALVDNMGNVIEDQAAEGNLVIL 468 Query: 487 IKSPSLFKEYW---KRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTN 630 P + + +R E T S G +F TGD DEDGY+ I GR + Sbjct: 469 DSWPGQMRTVYGDHERFEQTYFSTFKGMYF-TGDGARRDEDGYYWITGRVD 518
>ACSA_HUMAN (Q9NR19) Acetyl-coenzyme A synthetase, cytoplasmic (EC 6.2.1.1)| (Acetate--CoA ligase) (Acyl-activating enzyme) (Acetyl-CoA synthetase) (ACS) (AceCS) (Acyl-CoA synthetase short-chain family member 2) Length = 701 Score = 33.5 bits (75), Expect = 0.55 Identities = 29/107 (27%), Positives = 48/107 (44%), Gaps = 7/107 (6%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLHGAR--KEGTVGKPLPRVEAKIIMDDGTETK-DGVGELCIKS 495 +++ + TE + PL GA K G+ P V I+ + G E + + G L K Sbjct: 461 IVDTFWQTETGGHMLTPLPGATPMKPGSATFPFFGVAPAILNESGEELEGEAEGYLVFKQ 520 Query: 496 P--SLFKEYWKRPEVTAESFIDG--GFFKTGDTVTVDEDGYFIILGR 624 P + + + E ++ G++ TGD D+DGY+ I GR Sbjct: 521 PWPGIMRTVYGNHERFETTYFKKFPGYYVTGDGCQRDQDGYYWITGR 567
>ACSL4_MOUSE (Q9QUJ7) Long-chain-fatty-acid--CoA ligase 4 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 4) (LACS 4) (mACS4) Length = 711 Score = 33.5 bits (75), Expect = 0.55 Identities = 41/136 (30%), Positives = 60/136 (44%), Gaps = 10/136 (7%) Frame = +1 Query: 247 LRLMMCGSSALPSPLMKRWEEVT-CHRLLERYGMTEFVMALSNPLHGARKEGTVGKPLPR 423 +R+M+ G + L SP R+ V C + + YG+TE A + G VG PL Sbjct: 436 VRMMLYGGAPL-SPQTHRFMNVCLCCPIGQGYGLTESCGAGTVTEVTDYTTGRVGAPLIC 494 Query: 424 VEAKII--MDDGTETKDGV---GELCIKSPSLFKEYWKRPEVTAESF-IDGG---FFKTG 576 E K+ + G D GE+ I ++ Y+K E TAE + +D +F TG Sbjct: 495 CEIKLKDWQEGGYTVHDKPNPRGEIVIGGQNISMGYFKNEEKTAEDYCVDENGQRWFCTG 554 Query: 577 DTVTVDEDGYFIILGR 624 D DG I+ R Sbjct: 555 DIGEFHPDGCLQIIDR 570
>ACS1_ASHGO (Q758X0) Acetyl-coenzyme A synthetase 1 (EC 6.2.1.1) (Acetate--CoA| ligase 1) (Acyl-activating enzyme 1) Length = 694 Score = 33.5 bits (75), Expect = 0.55 Identities = 46/216 (21%), Positives = 82/216 (37%), Gaps = 13/216 (6%) Frame = +1 Query: 22 LFAPLYSGSVVEFMPKFSVRGVWQRWCESYPKGTSKNDEAITVFTGVPTVYTRLLQGYDS 201 ++ PL+SG + R+ + K ++T F PT L + DS Sbjct: 354 VYGPLFSGCTTVVFEGTPAYPSYSRYWDIIDK------YSVTQFYVAPTALRLLKRAGDS 407 Query: 202 MNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCHR---LLERYGMTEFVMALSN 372 Y+ + LR + + + + + + V R +++ Y TE L Sbjct: 408 Y------VDGYSLRTLRSLGTVGEPIAAEVWEWYYTVIGKREIPVIDTYWQTESGAHLVT 461 Query: 373 PLHGAR---KEGTVGKPLPRVEAKIIMDDGTETKDGV---GELCIKSP--SLFKEYWKRP 528 PL G K G+ P ++ I+ E G G L +K P S + W Sbjct: 462 PLAGGSTPMKPGSASFPFFGIDLAILDPQTGEELLGPNVEGVLAVKQPWPSFTRTIWNNH 521 Query: 529 EVTAESFIDG--GFFKTGDTVTVDEDGYFIILGRTN 630 + +++++ G++ GD D G+ ILGR + Sbjct: 522 DRYLDTYLNPYKGYYFAGDGAARDSQGFIWILGRVD 557
>ACSA_SHEON (Q8EDK3) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 650 Score = 33.5 bits (75), Expect = 0.55 Identities = 43/155 (27%), Positives = 65/155 (41%), Gaps = 12/155 (7%) Frame = +1 Query: 202 MNPDQQSACSYAAKQLRLMMCGSSALP-SPLMKRW-EEVTCHR---LLERYGMTEFVMAL 366 M +Q Y LR+M GS P +P RW EV H +++ + TE L Sbjct: 365 MAEGKQHFDKYNGSSLRIM--GSVGEPINPEAWRWYHEVIGHEHCPIVDTWWQTETGGIL 422 Query: 367 SNPLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKS--PSLFKEYWKRPE 531 PL GA K G+ +P V+ ++ + G + G L + P + + E Sbjct: 423 ITPLPGATDTKPGSATRPFFGVQPALVDNMGNILEGATEGNLVLLDSWPGQMRTVYGDHE 482 Query: 532 VTAESFIDG--GFFKTGDTVTVDEDGYFIILGRTN 630 ++ G + TGD DEDGY+ I GR + Sbjct: 483 RFVLTYFKTFRGMYFTGDGARRDEDGYYWITGRVD 517
>VRAA_STAAW (Q7A1Q0) Putative long chain fatty acid CoA ligase vraA (EC| 6.2.1.-) (Acyl-CoA synthetase) Length = 458 Score = 33.1 bits (74), Expect = 0.72 Identities = 30/100 (30%), Positives = 45/100 (45%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSL 504 L+E +G +E +S L+ +VG P VE K D +G+G +CIKS + Sbjct: 266 LIEFFGTSE-TSFISYNLNQQAPVESVGVLFPNVELKTTNHD----HNGIGTICIKSNMM 320 Query: 505 FKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 F Y V+ + + +F T D V E Y + GR Sbjct: 321 FSGY-----VSEQCINNDEWFVTNDNGYVKEQ-YLYLTGR 354
>VRAA_STAAU (Q9KWK5) Putative long chain fatty acid CoA ligase vraA (EC| 6.2.1.-) (Acyl-CoA synthetase) Length = 458 Score = 33.1 bits (74), Expect = 0.72 Identities = 30/100 (30%), Positives = 45/100 (45%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSL 504 L+E +G +E +S L+ +VG P VE K D +G+G +CIKS + Sbjct: 266 LIEFFGTSE-TSFISYNLNQQAPVESVGVLFPNVELKTTNHD----HNGIGTICIKSNMM 320 Query: 505 FKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 F Y V+ + + +F T D V E Y + GR Sbjct: 321 FSGY-----VSEQCINNDEWFVTNDNGYVKEQ-YLYLTGR 354
>VRAA_STAAS (Q6GBR2) Putative long chain fatty acid CoA ligase vraA (EC| 6.2.1.-) (Acyl-CoA synthetase) Length = 458 Score = 33.1 bits (74), Expect = 0.72 Identities = 30/100 (30%), Positives = 45/100 (45%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSL 504 L+E +G +E +S L+ +VG P VE K D +G+G +CIKS + Sbjct: 266 LIEFFGTSE-TSFISYNLNQQAPVESVGVLFPNVELKTTNHD----HNGIGTICIKSNMM 320 Query: 505 FKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 F Y V+ + + +F T D V E Y + GR Sbjct: 321 FSGY-----VSEQCINNDEWFVTNDNGYVKEQ-YLYLTGR 354
>VRAA_STAAR (Q6GJ94) Putative long chain fatty acid CoA ligase vraA (EC| 6.2.1.-) (Acyl-CoA synthetase) Length = 458 Score = 33.1 bits (74), Expect = 0.72 Identities = 40/155 (25%), Positives = 61/155 (39%) Frame = +1 Query: 160 VPTVYTRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCHRLLERY 339 VPT+ LL Y++ + Q S G S K + L+E + Sbjct: 222 VPTMIKSLLLVYNNEHTIQSFFSS-----------GDKLYSSIFKKIKNQANDINLIEFF 270 Query: 340 GMTEFVMALSNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYW 519 G +E +S L+ +VG P VE K D +G+G +C+KS +F Y Sbjct: 271 GTSE-TSFISYNLNQQAPVESVGVLFPNVELKTTNHD----HNGIGTICVKSNMMFSGY- 324 Query: 520 KRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 V+ + + +F T D V E Y + GR Sbjct: 325 ----VSEQCINNDEWFVTNDNGYVKEQ-YLYLTGR 354
>VRAA_STAAN (Q7A769) Putative long chain fatty acid CoA ligase vraA (EC| 6.2.1.-) (Acyl-CoA synthetase) Length = 458 Score = 33.1 bits (74), Expect = 0.72 Identities = 30/100 (30%), Positives = 45/100 (45%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSL 504 L+E +G +E +S L+ +VG P VE K D +G+G +CIKS + Sbjct: 266 LIEFFGTSE-TSFISYNLNQQAPVESVGVLFPNVELKTTNHD----HNGIGTICIKSNMM 320 Query: 505 FKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 F Y V+ + + +F T D V E Y + GR Sbjct: 321 FSGY-----VSEQCINNDEWFVTNDNGYVKEQ-YLYLTGR 354
>VRAA_STAAM (Q99W34) Putative long chain fatty acid CoA ligase vraA (EC| 6.2.1.-) (Acyl-CoA synthetase) Length = 458 Score = 33.1 bits (74), Expect = 0.72 Identities = 30/100 (30%), Positives = 45/100 (45%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSL 504 L+E +G +E +S L+ +VG P VE K D +G+G +CIKS + Sbjct: 266 LIEFFGTSE-TSFISYNLNQQAPVESVGVLFPNVELKTTNHD----HNGIGTICIKSNMM 320 Query: 505 FKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 F Y V+ + + +F T D V E Y + GR Sbjct: 321 FSGY-----VSEQCINNDEWFVTNDNGYVKEQ-YLYLTGR 354
>VRAA_STAAC (Q5HIA1) Putative long chain fatty acid CoA ligase vraA (EC| 6.2.1.-) (Acyl-CoA synthetase) Length = 458 Score = 33.1 bits (74), Expect = 0.72 Identities = 30/100 (30%), Positives = 45/100 (45%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSL 504 L+E +G +E +S L+ +VG P VE K D +G+G +CIKS + Sbjct: 266 LIEFFGTSE-TSFISYNLNQQAPVESVGVLFPNVELKTTNHD----HNGIGTICIKSNMM 320 Query: 505 FKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 F Y V+ + + +F T D V E Y + GR Sbjct: 321 FSGY-----VSEQCINNDEWFVTNDNGYVKEQ-YLYLTGR 354
>ACSA_EMENI (P16928) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 670 Score = 33.1 bits (74), Expect = 0.72 Identities = 30/111 (27%), Positives = 47/111 (42%), Gaps = 9/111 (8%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDG---VGELCI 489 + + Y TE + PL G K G+ P +E II E G G L Sbjct: 426 ICDTYWQTETGSNVITPLAGVTPTKPGSASLPFFGIEPAIIDPVSGEEISGNDVEGVLAF 485 Query: 490 KSP--SLFKEYWKRPEVTAESFID--GGFFKTGDTVTVDEDGYFIILGRTN 630 K P S+ + W + ++++ G++ TGD D +GY+ I GR + Sbjct: 486 KQPWPSMARTVWGAHKRYMDTYLQVYKGYYFTGDGAGRDHEGYYWIRGRVD 536
>DLTA_LISMO (Q8Y8D4) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 510 Score = 33.1 bits (74), Expect = 0.72 Identities = 37/143 (25%), Positives = 63/143 (44%), Gaps = 13/143 (9%) Frame = +1 Query: 250 RLMMCG---SSALPSPLMKRWEEVTCHRLLERYGMTEFVMALSN-----PLHGARKEGTV 405 R + CG + S L+ R+ + + YG TE +A++ + A + Sbjct: 270 RFLFCGEVLAKKTASELLDRFPDAVIYNT---YGPTEATVAVTQVKVTREIIDAYPSLPL 326 Query: 406 GKPLPRVEAKII-MDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFID-GGF--FK 570 G P + I+ + G +G GE+ + S+ K Y PE T + F D G+ ++ Sbjct: 327 GVIKPDMRLHIVDQETGEVLPEGEKGEIVLIGASVSKGYLNEPEKTDQVFFDYKGYQAYR 386 Query: 571 TGDTVTVDEDGYFIILGRTNADI 639 TGD+ + +DGY GR + I Sbjct: 387 TGDSGII-KDGYLFFQGRLDFQI 408
>ACSA2_PSEPK (Q88DW6) Acetyl-coenzyme A synthetase 2 (EC 6.2.1.1) (Acetate--CoA| ligase 2) (Acyl-activating enzyme 2) Length = 644 Score = 32.7 bits (73), Expect = 0.94 Identities = 46/173 (26%), Positives = 77/173 (44%), Gaps = 12/173 (6%) Frame = +1 Query: 142 ITVFTGVPTVYTRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALP-SPLMKRW--EEV 312 + +F PT L++ + P Q S + K LRL+ GS P +P W EEV Sbjct: 347 VNIFYTAPTALRALMR--EGSAPLQ----STSRKSLRLL--GSVGEPINPEAWEWYFEEV 398 Query: 313 TCHR--LLERYGMTEFVMALSNPLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKD-GVG 477 R +++ + TE + PL G + K G +P+ V+ ++ + G + G G Sbjct: 399 GQKRCPIVDTWWQTETGGIMLTPLPGTQSLKPGCATQPMFGVQPVLLDEKGKLIEGPGAG 458 Query: 478 ELCIKS--PSLFKEYWKRPEVTAESFIDG--GFFKTGDTVTVDEDGYFIILGR 624 L IK+ P + + + +++ G++ TGD D DG + I GR Sbjct: 459 VLAIKASWPGQIRSVYGDHQRMVDTYFKPLPGYYFTGDGARRDADGDYWITGR 511
>PRPE_SALTY (P55912) Propionate--CoA ligase (EC 6.2.1.17) (Propionyl-CoA| synthetase) Length = 628 Score = 32.7 bits (73), Expect = 0.94 Identities = 55/220 (25%), Positives = 83/220 (37%), Gaps = 17/220 (7%) Frame = +1 Query: 22 LFAPLYSGS---VVEFMPKFSVRGVWQRWCESYPKGTSKN-DEAITVFTGVPTVYTRLLQ 189 ++APL +G V E +P + GVW + E Y + AI V PT R Sbjct: 293 VYAPLLAGMATIVYEGLPTYPDCGVWWKIVEKYQVNRMFSAPTAIRVLKKFPTAQIR--- 349 Query: 190 GYDSMNPDQQSACSYAAKQLRLMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEF---VM 360 N D S L + L P E +++ Y TE +M Sbjct: 350 -----NHDLSS--------LEALYLAGEPLDEPTASWVTETLGVPVIDNYWQTESGWPIM 396 Query: 361 ALSNPLHGARKE-GTVGKPLPRVEAKIIMDDGTETKDGVGE---LCIKSP---SLFKEYW 519 AL+ L G+ G P+ +++ ++ T G+ E L I+ P + W Sbjct: 397 ALARALDDRPSRLGSPGVPMYGYNVQLL-NEVTGEPCGINEKGMLVIEGPLPPGCIQTIW 455 Query: 520 ---KRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTN 630 R T S + + T D D +GY+ ILGRT+ Sbjct: 456 GDDARFVKTYWSLFNRQVYATFDWGIRDAEGYYFILGRTD 495
>ACSA_COPCI (O13440) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 661 Score = 32.7 bits (73), Expect = 0.94 Identities = 55/220 (25%), Positives = 88/220 (40%), Gaps = 17/220 (7%) Frame = +1 Query: 22 LFAPLYSGSVVEFMPKFSVRGVWQRWCESYPKGTSKNDEAITVFTGVPTVYTRLLQ--GY 195 ++ PL G+ V R+ E+ K +T F PT RLL+ G+ Sbjct: 323 VYGPLAIGATTTVFESTPVYPTPSRYWETVEK------YKLTQFYSAPTAI-RLLRRLGH 375 Query: 196 DSMNPDQQSACSYAAKQLRLMMCGSSALP-SPLMKRW--EEV--TCHRLLERYGMTEFVM 360 + +N S+ L + GS P +P W E V T +++ + TE Sbjct: 376 EHVNKHDLSS---------LRVLGSVGEPINPEAWHWYNEHVGKTECAIVDTFWQTETGS 426 Query: 361 ALSNPLHGA--RKEGTVGKPLPRVEAKIIMD------DGTETKDGVGELCIKSPSLFKEY 516 + P GA K G P +E I+ +G + +GV + PS+ + Sbjct: 427 IVVTPFPGAIETKPGAATVPFFGIEPAILEPTTGKVLEGNDV-EGVLTIAHPWPSIARTI 485 Query: 517 WKRPEVTAESFIDG--GFFKTGDTVTVDEDGYFIILGRTN 630 + + E+++ G+F TGD DEDGY I GR + Sbjct: 486 YGDHQRYLETYMKPYPGYFYTGDGAARDEDGYIWIKGRVD 525
>ACSA_YERPE (Q8D1G8) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 652 Score = 32.7 bits (73), Expect = 0.94 Identities = 34/112 (30%), Positives = 57/112 (50%), Gaps = 10/112 (8%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGV--GELCI- 489 +++ + TE + PL GA K G+ +P V+ ++ D+ ++GV G L I Sbjct: 409 IVDTWWQTETGGFMITPLPGATELKAGSATRPFFGVQPALV-DNLGNPQEGVAEGNLVIT 467 Query: 490 -----KSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTN 630 ++ +LF ++ +R E T S G +F +GD DEDGY+ I GR + Sbjct: 468 DSWPGQARTLFGDH-ERFEQTYFSTFKGMYF-SGDGARRDEDGYYWITGRVD 517
>DLTA_LISIN (Q92D47) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 510 Score = 32.7 bits (73), Expect = 0.94 Identities = 38/143 (26%), Positives = 62/143 (43%), Gaps = 13/143 (9%) Frame = +1 Query: 250 RLMMCG---SSALPSPLMKRWEEVTCHRLLERYGMTEFVMALSN-----PLHGARKEGTV 405 R + CG + S L+ R+ + + YG TE +A++ L A + Sbjct: 270 RFLFCGEVLAKKTASELLDRFPDAVIYNT---YGPTEATVAVTQVKVTRELIDAYPSLPL 326 Query: 406 GKPLPRVEAKII-MDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFID-GGF--FK 570 G P + I+ + G +G GE+ + S+ K Y PE T + F D G+ + Sbjct: 327 GVIKPDMRLHIVDQETGEILPEGEKGEIILIGASVSKGYLNEPEKTDQVFFDYKGYQAYH 386 Query: 571 TGDTVTVDEDGYFIILGRTNADI 639 TGD+ + +DGY GR + I Sbjct: 387 TGDSGVI-KDGYLFFQGRLDFQI 408
>ACSA1_PSEPK (Q88EH6) Acetyl-coenzyme A synthetase 1 (EC 6.2.1.1) (Acetate--CoA| ligase 1) (Acyl-activating enzyme 1) Length = 653 Score = 32.3 bits (72), Expect = 1.2 Identities = 33/112 (29%), Positives = 54/112 (48%), Gaps = 10/112 (8%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGV--GELCI- 489 +++ + TE L +PL GA K G+ +P V ++ D+ DG G L I Sbjct: 409 IVDTWWQTETGGILISPLPGATGLKPGSATRPFFGVVPALV-DNLGNLIDGAAEGNLVIL 467 Query: 490 -----KSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTN 630 +S SL+ ++ + + ++F G + TGD DEDGY+ I GR + Sbjct: 468 DSWPGQSRSLYGDHDRFVDTYFKTF--RGMYFTGDGARRDEDGYYWITGRVD 517
>ACSA_RHILO (Q98ET8) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 651 Score = 32.3 bits (72), Expect = 1.2 Identities = 28/109 (25%), Positives = 49/109 (44%), Gaps = 7/109 (6%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKS 495 +++ + TE L PL GA K G+ +P V+ +++ +G + G LCI Sbjct: 410 IVDTWWQTETGGILITPLPGATDLKAGSATRPFFGVKPQLVDGEGKVLEGAADGNLCITD 469 Query: 496 --PSLFKEYWKRPEVTAESFIDG--GFFKTGDTVTVDEDGYFIILGRTN 630 P + + + +++ G + TGD D DGY+ I GR + Sbjct: 470 SWPGQMRTVYGDHDRFVQTYFSTYKGKYFTGDGCRRDADGYYWITGRVD 518
>ACSA_MOUSE (Q9QXG4) Acetyl-coenzyme A synthetase, cytoplasmic (EC 6.2.1.1)| (Acetate--CoA ligase) (Acyl-activating enzyme) (Acetyl-CoA synthetase) (ACS) (AceCS) (Acyl-CoA synthetase short-chain family member 2) Length = 701 Score = 32.0 bits (71), Expect = 1.6 Identities = 28/109 (25%), Positives = 49/109 (44%), Gaps = 9/109 (8%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLHGAR--KEGTVGKPLPRVEAKIIMDDGTETK-DGVGELCIKS 495 +++ + TE + PL GA K G+ P V + + + G E + + G L K Sbjct: 461 IVDTFWQTETGGHMLTPLPGATPMKPGSASFPFFGVALQSLNESGEELEGEAEGYLVFKQ 520 Query: 496 P------SLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGR 624 P +++ + + + F G++ TGD D+DGY+ I GR Sbjct: 521 PWPGIMRTVYGNHTRFETTYFKKF--PGYYVTGDGCRRDQDGYYWITGR 567
>ACSA_VIBCH (Q9KV59) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 649 Score = 32.0 bits (71), Expect = 1.6 Identities = 34/111 (30%), Positives = 50/111 (45%), Gaps = 9/111 (8%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGVGE----LC 486 +++ + TE L PL GA K G+ +P V+ ++ D+ E +G E L Sbjct: 409 IVDTWWQTETGGILITPLPGATALKPGSATRPFFGVQPALV-DNMGEIVEGATEGNLVLL 467 Query: 487 IKSPSLFKEYW---KRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTN 630 P + + R E T S G +F TGD DEDGY+ I GR + Sbjct: 468 DSWPGQMRTVYGDHDRFEQTYFSTFKGMYF-TGDGARRDEDGYYWITGRVD 517
>ACSA_XANAC (Q8PF09) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 647 Score = 32.0 bits (71), Expect = 1.6 Identities = 48/176 (27%), Positives = 78/176 (44%), Gaps = 13/176 (7%) Frame = +1 Query: 142 ITVFTGVPTVYTRLLQGYDSMNPDQQSACSYAAKQLRLMMCGSSALP-SPLMKRW--EEV 312 +T+F PT L++ D +P ++++ K LRL+ GS P +P RW E V Sbjct: 350 VTIFYTAPTAIRALMR--DGADPVKKTS----RKSLRLL--GSVGEPINPEAWRWYYEVV 401 Query: 313 TCHR--LLERYGMTEFVMALSNPLHGA--RKEGTVGKPLPRVEAKIIMDDGTETKDGVGE 480 R +++ + TE L +PL GA K G+ P V+ ++ +G + +G E Sbjct: 402 GDSRCPIVDTWWQTETGGILISPLAGAVDLKPGSATLPFFGVQPALVDAEG-KILEGATE 460 Query: 481 LCIKSPSLFKEYWKRPEVTAESFIDG------GFFKTGDTVTVDEDGYFIILGRTN 630 + + + + FID G + TGD D DGY+ I GR + Sbjct: 461 GNLVLLDSWPGQMRSVYGDHQRFIDTYFRTYPGSYFTGDGCRRDADGYYWITGRVD 516
>ACSA_NEUCR (P16929) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 667 Score = 32.0 bits (71), Expect = 1.6 Identities = 27/112 (24%), Positives = 48/112 (42%), Gaps = 9/112 (8%) Frame = +1 Query: 322 RLLERYGMTEFVMALSNPLHGAR--KEGTVGKPLPRVEAKII---MDDGTETKDGVGELC 486 ++ + Y TE + PL G K G+ P +E ++ + D G L Sbjct: 423 QICDTYWQTETGSNVITPLAGVTPTKPGSASFPFFGIEPALVDPVTGEEIHGNDVEGVLA 482 Query: 487 IKSP--SLFKEYWKRPEVTAESFID--GGFFKTGDTVTVDEDGYFIILGRTN 630 K P S+ + W + E+++ G++ TGD D +G++ I GR + Sbjct: 483 FKQPWPSMARTVWGAHKRYMETYLHVYKGYYFTGDGAARDHEGFYWIRGRVD 534
>PUR2_METAC (Q8TKT6) Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (GARS)| (Glycinamide ribonucleotide synthetase) (Phosphoribosylglycinamide synthetase) Length = 441 Score = 32.0 bits (71), Expect = 1.6 Identities = 24/85 (28%), Positives = 37/85 (43%) Frame = +1 Query: 304 EEVTCHRLLERYGMTEFVMALSNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGVGEL 483 EE H +E+ G V + L G + +G LP ++A KD EL Sbjct: 131 EEAPAHAFIEKLGD---VAVKPSGLTGGKGVKVMGDQLPDLKA---------AKDYTSEL 178 Query: 484 CIKSPSLFKEYWKRPEVTAESFIDG 558 K P + +E + E T ++F+DG Sbjct: 179 LEKGPVVIEERFIGEEFTLQAFVDG 203
>ACSA_VIBPA (Q87KU7) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 650 Score = 32.0 bits (71), Expect = 1.6 Identities = 32/111 (28%), Positives = 50/111 (45%), Gaps = 9/111 (8%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGVGE----LC 486 +++ + TE L PL GA K G+ +P V+ ++ + G +D V E + Sbjct: 409 IVDTWWQTETGGILIAPLPGATDLKPGSATRPFFGVQPALVDNMGNILEDTVAEGNLVIL 468 Query: 487 IKSPSLFKEYW---KRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTN 630 P + + +R E T S G +F T D DEDGY+ I GR + Sbjct: 469 DSWPGQMRTVYGDHERFEQTYFSTFKGMYF-TSDGARRDEDGYYWITGRVD 518
>ACSA_ECOLI (P27550) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 652 Score = 31.6 bits (70), Expect = 2.1 Identities = 31/111 (27%), Positives = 54/111 (48%), Gaps = 9/111 (8%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCI-- 489 +++ + TE + PL GA K G+ +P V+ ++ ++G + G L I Sbjct: 409 VVDTWWQTETGGFMITPLPGATELKAGSATRPFFGVQPALVDNEGNPLEGATEGSLVITD 468 Query: 490 ----KSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTN 630 ++ +LF ++ +R E T S +F +GD DEDGY+ I GR + Sbjct: 469 SWPGQARTLFGDH-ERFEQTYFSTFKNMYF-SGDGARRDEDGYYWITGRVD 517
>ACSA_ECOL6 (Q8FAY8) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 652 Score = 31.6 bits (70), Expect = 2.1 Identities = 31/111 (27%), Positives = 54/111 (48%), Gaps = 9/111 (8%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCI-- 489 +++ + TE + PL GA K G+ +P V+ ++ ++G + G L I Sbjct: 409 VVDTWWQTETGGFMITPLPGATELKAGSATRPFFGVQPALVDNEGNPLEGATEGSLVITD 468 Query: 490 ----KSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTN 630 ++ +LF ++ +R E T S +F +GD DEDGY+ I GR + Sbjct: 469 SWPGQARTLFGDH-ERFEQTYFSTFKNMYF-SGDGARRDEDGYYWITGRVD 517
>SYFB_STRCO (O88054) Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20)| (Phenylalanine--tRNA ligase beta chain) (PheRS) Length = 840 Score = 31.2 bits (69), Expect = 2.7 Identities = 38/143 (26%), Positives = 60/143 (41%), Gaps = 4/143 (2%) Frame = +1 Query: 73 SVRGVWQRWCESYPKGTSKNDEAITVFTGVPTVYTRLLQGYDSMNPDQQSACSYAAKQLR 252 S+RGV + +Y G D A+ G P Y GY D + A+ + Sbjct: 180 SIRGVARETAIAY--GLPLRDPALLDVPG-PNAY-----GYPVKIADPTGCDRFTARTVT 231 Query: 253 LMMCGSSALPSPLMKRWEEVTCHRLLERYGMTEFVMA-LSNPLHGARK---EGTVGKPLP 420 + + + P L +R ++V + +T +VM L PLH + +GT+G Sbjct: 232 GLSAEARS-PIWLQRRLQKVGMRPISLAVDVTNYVMMELGQPLHAYDRSLVQGTIGVRRA 290 Query: 421 RVEAKIIMDDGTETKDGVGELCI 489 + KI+ DGTE K +L I Sbjct: 291 QEGEKIVTLDGTERKLHAEDLVI 313
>ACSA_AGRRH (Q9KWA3) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 652 Score = 31.2 bits (69), Expect = 2.7 Identities = 30/111 (27%), Positives = 54/111 (48%), Gaps = 9/111 (8%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCI-- 489 +++ + TE + PL GA K G+ +P + +++ +G + G LCI Sbjct: 409 VVDTWWQTETGGIMITPLPGATDLKPGSATRPFFGIRPELVDAEGKLIEGAADGNLCIAD 468 Query: 490 ----KSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTN 630 ++ S++ ++ +R T S +G +F TGD D DGY+ I GR + Sbjct: 469 SWPGQARSVYGDH-ERFIQTYFSTYEGKYF-TGDGCRRDADGYYWITGRVD 517
>FAD26_MYCTU (Q10976) Putative fatty-acid--CoA ligase fadD26 (EC 6.2.1.-)| (Acyl-CoA synthetase) Length = 583 Score = 31.2 bits (69), Expect = 2.7 Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 11/62 (17%) Frame = +1 Query: 472 VGELCIKSPSLFKEYWKRPEVTAESF-----------IDGGFFKTGDTVTVDEDGYFIIL 618 VGE+ + + YW++P+ TA+ F +G + +TGD + V DG I+ Sbjct: 402 VGEIWVHGDHVTMGYWQKPKQTAQVFDAKLVDPAPAAPEGPWLRTGD-LGVISDGELFIM 460 Query: 619 GR 624 GR Sbjct: 461 GR 462
>ACSA_PRB01 (Q9F7R5) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 641 Score = 30.8 bits (68), Expect = 3.6 Identities = 29/111 (26%), Positives = 49/111 (44%), Gaps = 9/111 (8%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLHGAR--KEGTVGKPLPRVEAKIIMDDGTETK-DGVGELCIKS 495 +++ + TE L +P+ G K G+ P V+ + + G + G L I+ Sbjct: 402 VIDTWWQTETGSVLISPIAGITPTKPGSATLPFFGVKPSLYDEHGNTLEGSNAGNLVIEQ 461 Query: 496 --PSLFKEYWKRPEVTAESFIDGGFFK----TGDTVTVDEDGYFIILGRTN 630 PS + + + +++ G +K TGD DEDGYF I GR + Sbjct: 462 SWPSQIRSIYGDHQRMIDTYF--GMYKDIYFTGDGARRDEDGYFWITGRVD 510
>ACSA_PSESM (Q885K7) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 651 Score = 30.8 bits (68), Expect = 3.6 Identities = 30/111 (27%), Positives = 53/111 (47%), Gaps = 9/111 (8%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCI-- 489 +++ + TE L +PL GA K G+ +P V ++ + G + G L I Sbjct: 409 IVDTWWQTETGGILISPLPGATALKPGSATRPFFGVIPALVDNLGNLIEGAAEGNLVILD 468 Query: 490 ----KSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTN 630 +S +L+ ++ + + ++F G + TGD DEDGY+ I GR + Sbjct: 469 SWPGQSRTLYGDHDRFVDTYFKTF--RGMYFTGDGARRDEDGYYWITGRVD 517
>FAD25_MYCTU (Q50586) Putative fatty-acid--CoA ligase fadD25 (EC 6.2.1.-)| (Acyl-CoA synthetase) Length = 583 Score = 30.8 bits (68), Expect = 3.6 Identities = 21/72 (29%), Positives = 34/72 (47%), Gaps = 12/72 (16%) Frame = +1 Query: 445 DDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESFI-----------DGGFFKTGDTVT 588 D G E G +GE+ + ++ YW++PE T +F G + +TGD+ Sbjct: 394 DTGIERPAGTIGEIWVHGDNVAIGYWQKPEATERTFSATIVNPSEGTPAGPWLRTGDSGF 453 Query: 589 VDEDGYFIILGR 624 + E G I+GR Sbjct: 454 LSE-GELFIMGR 464
>AKR1_SACKL (Q875S9) Palmitoyltransferase AKR1 (EC 2.3.1.-) (Ankyrin| repeat-containing protein AKR1) Length = 737 Score = 30.4 bits (67), Expect = 4.7 Identities = 16/47 (34%), Positives = 21/47 (44%) Frame = -3 Query: 549 K*FCSNLWSFPVLFEKGWTFNTELTDSIFSFCTIIHNDLGLNTWKRF 409 K FC + W + K F+ L FC I+ND+GL K F Sbjct: 449 KHFCISTWVRKPIRSKFSNFSRALVTRFDHFCPWIYNDIGLRNHKTF 495
>ACSA_SALTY (Q8ZKF6) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 652 Score = 30.4 bits (67), Expect = 4.7 Identities = 31/111 (27%), Positives = 54/111 (48%), Gaps = 9/111 (8%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLHGA--RKEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCI-- 489 +++ + TE + PL GA K G+ +P V+ ++ ++G + G L I Sbjct: 409 VVDTWWQTETGGFMITPLPGAIELKAGSATRPFFGVQPALVDNEGHPQEGATEGNLVITD 468 Query: 490 ----KSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTN 630 ++ +LF ++ +R E T S +F +GD DEDGY+ I GR + Sbjct: 469 SWPGQARTLFGDH-ERFEQTYFSTFKNMYF-SGDGARRDEDGYYWITGRVD 517
>ACSA_SALTI (Q8Z1R0) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 652 Score = 30.4 bits (67), Expect = 4.7 Identities = 31/111 (27%), Positives = 54/111 (48%), Gaps = 9/111 (8%) Frame = +1 Query: 325 LLERYGMTEFVMALSNPLHGA--RKEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCI-- 489 +++ + TE + PL GA K G+ +P V+ ++ ++G + G L I Sbjct: 409 VVDTWWQTETGGFMITPLPGAIELKAGSATRPFFGVQPALVDNEGHPQEGATEGNLVITD 468 Query: 490 ----KSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTN 630 ++ +LF ++ +R E T S +F +GD DEDGY+ I GR + Sbjct: 469 SWPGQARTLFGDH-ERFEQTYFSTFKNMYF-SGDGARRDEDGYYWITGRVD 517
>PUR2_METMA (Q8Q0J2) Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (GARS)| (Glycinamide ribonucleotide synthetase) (Phosphoribosylglycinamide synthetase) Length = 435 Score = 30.0 bits (66), Expect = 6.1 Identities = 22/85 (25%), Positives = 37/85 (43%) Frame = +1 Query: 304 EEVTCHRLLERYGMTEFVMALSNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGVGEL 483 EE H +E+ G V + L G + +G LP ++A ++ EL Sbjct: 131 EEAPAHAFIEKLGD---VAVKPSGLTGGKGVKVMGDQLPDIKA---------AREYTSEL 178 Query: 484 CIKSPSLFKEYWKRPEVTAESFIDG 558 K P + +E + E T ++F+DG Sbjct: 179 LEKGPVVIEERFIGEEFTLQAFVDG 203
>AKR1_SACCA (Q876A6) Palmitoyltransferase AKR1 (EC 2.3.1.-) (Ankyrin| repeat-containing protein AKR1) (Fragments) Length = 742 Score = 30.0 bits (66), Expect = 6.1 Identities = 17/47 (36%), Positives = 19/47 (40%) Frame = -3 Query: 549 K*FCSNLWSFPVLFEKGWTFNTELTDSIFSFCTIIHNDLGLNTWKRF 409 K FC W L T NT FC I+ND+GL K F Sbjct: 439 KNFCLETWIRKPLRSHFSTLNTHNVARFDHFCPWIYNDIGLKNHKNF 485
>ASTE_VIBCH (Q9KSL4) Succinylglutamate desuccinylase (EC 3.1.-.-)| Length = 342 Score = 29.6 bits (65), Expect = 8.0 Identities = 14/44 (31%), Positives = 23/44 (52%), Gaps = 4/44 (9%) Frame = +2 Query: 359 WHCLIHCMVHGKKVQSVNLF----HVLRPRSLWMMVQKLKMESV 478 WH +HC + G K S + H +R RSL +++ +E+V Sbjct: 150 WHLDLHCAIRGSKHYSFAVSPKARHPVRSRSLMQFIEQAHIEAV 193
>DGA1_ASHGO (Q75BY0) Diacylglycerol O-acyltransferase 1 (EC 2.3.1.20)| Length = 461 Score = 29.6 bits (65), Expect = 8.0 Identities = 12/46 (26%), Positives = 21/46 (45%) Frame = +1 Query: 28 APLYSGSVVEFMPKFSVRGVWQRWCESYPKGTSKNDEAITVFTGVP 165 +P G V + P+ +W+ +CE YP K+++ F P Sbjct: 145 SPANGGVVRRYSPRLRSLALWRYYCEYYPISLHKSEDLAPTFVPDP 190 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 98,524,363 Number of Sequences: 219361 Number of extensions: 2135956 Number of successful extensions: 5756 Number of sequences better than 10.0: 243 Number of HSP's better than 10.0 without gapping: 5420 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5646 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 6029593548 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
