ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | baal33h11 |
|---|---|
| Clone Library Name | barley_pub |
>SAPK2_ORYSA (Q84TC6) Serine/threonine-protein kinase SAPK2 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 2) Length = 339 Score = 322 bits (825), Expect = 6e-88 Identities = 160/195 (82%), Positives = 169/195 (86%) Frame = +2 Query: 2 SKSSVLHSQPKSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEP 181 SKSS+LHSQPKSTVGTPAYIAPEVL+R+EYDGKVADVWSCGVTLYVMLVGAYPFEDPDEP Sbjct: 147 SKSSLLHSQPKSTVGTPAYIAPEVLARKEYDGKVADVWSCGVTLYVMLVGAYPFEDPDEP 206 Query: 182 KNFRKTITRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPI 361 +NFRKTITRILSVQY VPDYVR+SMECRHLLSRIFVANPEQRITI EIKNHPWFLKNLPI Sbjct: 207 RNFRKTITRILSVQYMVPDYVRVSMECRHLLSRIFVANPEQRITIPEIKNHPWFLKNLPI 266 Query: 362 EMTDEYQMSLHMVGVNAPPQSLEEIMAIIQEARIPGDGSKFAGQLSVPGLGSMELXXXXX 541 EMTDEYQMS+ M +N P Q LEEIMAIIQEAR PGDGSKF+GQ +PGLGSMEL Sbjct: 267 EMTDEYQMSVQMNDINTPSQGLEEIMAIIQEARKPGDGSKFSGQ--IPGLGSMELDDVDT 324 Query: 542 XXXXXXXXXXFVCAL 586 FVCAL Sbjct: 325 DDIDVEDSGDFVCAL 339
>SAPK1_ORYSA (Q75LR7) Serine/threonine-protein kinase SAPK1 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 1) Length = 342 Score = 301 bits (772), Expect = 8e-82 Identities = 151/196 (77%), Positives = 162/196 (82%), Gaps = 1/196 (0%) Frame = +2 Query: 2 SKSSVLHSQPKSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEP 181 SKSSVLHSQPKSTVGTPAYIAPEVLSR+EYDGKVADVWSCGVTLYVMLVGAYPFEDPD+P Sbjct: 147 SKSSVLHSQPKSTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLVGAYPFEDPDDP 206 Query: 182 KNFRKTITRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPI 361 +NFRKTITRILSVQYS+PDYVR+S +CRHLLSRIFV NPEQRITI EIKNHPWFLKNLPI Sbjct: 207 RNFRKTITRILSVQYSIPDYVRVSADCRHLLSRIFVGNPEQRITIPEIKNHPWFLKNLPI 266 Query: 362 EMTDEYQMSLHMVGVNAPPQSLEEIMAIIQEARIPGDGSKFAGQLSVPGLGSMEL-XXXX 538 EMTDEYQ S+ + +N P QSLEE+MAIIQEAR PGD K AG V LGSM+L Sbjct: 267 EMTDEYQRSMQLADMNTPSQSLEEVMAIIQEARKPGDAMKLAGAGQVACLGSMDLDDIDD 326 Query: 539 XXXXXXXXXXXFVCAL 586 FVCAL Sbjct: 327 IDDIDIENSGDFVCAL 342
>AAIP_WHEAT (Q02066) Abscisic acid-inducible protein kinase (EC 2.7.11.1)| (Fragment) Length = 332 Score = 288 bits (738), Expect = 7e-78 Identities = 144/176 (81%), Positives = 157/176 (89%), Gaps = 1/176 (0%) Frame = +2 Query: 2 SKSSVLHSQPKSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEP 181 SKSSVLHSQPKSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEP Sbjct: 137 SKSSVLHSQPKSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEP 196 Query: 182 KNFRKTITRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPI 361 +NFRKTITRILSVQYSVPDYVR+SM+C HLLSRIFV NP+QRITI EIKNHPWFLK LP+ Sbjct: 197 RNFRKTITRILSVQYSVPDYVRVSMDCIHLLSRIFVGNPQQRITIPEIKNHPWFLKRLPV 256 Query: 362 EMTDEYQMSLHMVGVNAPPQSLEEIMAIIQEARIPGDGS-KFAGQLSVPGLGSMEL 526 EMTDEYQ S+ + +N P QSLEE MAIIQEA+ PGD + AGQ++ LGSM+L Sbjct: 257 EMTDEYQRSMQLADMNTPSQSLEEAMAIIQEAQKPGDNALGVAGQVAC--LGSMDL 310
>SAPKA_ORYSA (Q75H77) Serine/threonine-protein kinase SAPK10 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 10) Length = 362 Score = 246 bits (627), Expect = 5e-65 Identities = 121/170 (71%), Positives = 136/170 (80%) Frame = +2 Query: 2 SKSSVLHSQPKSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEP 181 SKSSVLHSQPKSTVGTPAYIAPEVL ++EYDGK+ADVWSCGVTLYVMLVGAYPFEDPDEP Sbjct: 166 SKSSVLHSQPKSTVGTPAYIAPEVLLKKEYDGKIADVWSCGVTLYVMLVGAYPFEDPDEP 225 Query: 182 KNFRKTITRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPI 361 KNFRKTI RIL VQYS+PDYV IS ECR L++RIFVANP RI+I EI+NHPWFLKNLP Sbjct: 226 KNFRKTIQRILGVQYSIPDYVHISPECRDLIARIFVANPATRISIPEIRNHPWFLKNLPA 285 Query: 362 EMTDEYQMSLHMVGVNAPPQSLEEIMAIIQEARIPGDGSKFAGQLSVPGL 511 ++ D+ +MS P QS++EIM I+ EA IP GS Q GL Sbjct: 286 DLMDDSKMSSQYEEPEQPMQSMDEIMQILAEATIPAAGSGGINQFLNDGL 335
>SAPK7_ORYSA (Q7XQP4) Serine/threonine-protein kinase SAPK7 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 7) Length = 359 Score = 241 bits (615), Expect = 1e-63 Identities = 116/158 (73%), Positives = 135/158 (85%), Gaps = 3/158 (1%) Frame = +2 Query: 2 SKSSVLHSQPKSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEP 181 SKSS+LHS+PKSTVGTPAYIAPEVLSRREYDGK ADVWSCGVTLYVMLVGAYPFEDPD+P Sbjct: 147 SKSSLLHSKPKSTVGTPAYIAPEVLSRREYDGKTADVWSCGVTLYVMLVGAYPFEDPDDP 206 Query: 182 KNFRKTITRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPI 361 KNFRKTI RI+S+QY +P+YV +S +CR LLSRIFVANP +RITI+EI+NHPWFLKNLP Sbjct: 207 KNFRKTIGRIMSIQYKIPEYVHVSQDCRQLLSRIFVANPAKRITIREIRNHPWFLKNLPR 266 Query: 362 EMTDEYQMSLHMVGVNAPP---QSLEEIMAIIQEARIP 466 E+T+ Q + +AP QS+EEIM I++EAR P Sbjct: 267 ELTEAAQAMYYKKDNSAPTYSVQSVEEIMKIVEEARTP 304
>SAPK3_ORYSA (Q75V63) Serine/threonine-protein kinase SAPK3 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 3) (Protein kinase REK) Length = 334 Score = 238 bits (606), Expect = 1e-62 Identities = 112/157 (71%), Positives = 134/157 (85%) Frame = +2 Query: 2 SKSSVLHSQPKSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEP 181 SKS++LHS+PKSTVGTPAYIAPEVLSR+EYDGKVADVWSCGVTLYVMLVG+YPFEDP +P Sbjct: 148 SKSALLHSKPKSTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLVGSYPFEDPGDP 207 Query: 182 KNFRKTITRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPI 361 +NFRKTI+RIL VQYS+PDYVR+S +CR LLS+IFVA+P +RITI EIK H WFLKNLP Sbjct: 208 RNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFVADPSKRITIPEIKKHTWFLKNLPK 267 Query: 362 EMTDEYQMSLHMVGVNAPPQSLEEIMAIIQEARIPGD 472 E+++ + P Q++EEIM IIQEA++PGD Sbjct: 268 EISEREKADYKDTDAAPPTQAVEEIMRIIQEAKVPGD 304
>SAPK6_ORYSA (Q6ZI44) Serine/threonine-protein kinase SAPK6 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 6) Length = 365 Score = 236 bits (602), Expect = 4e-62 Identities = 114/162 (70%), Positives = 136/162 (83%), Gaps = 3/162 (1%) Frame = +2 Query: 2 SKSSVLHSQPKSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEP 181 SKSS+LHS+PKSTVGTPAYIAPEVLSRREYDGK+ADVWSCGVTLYVMLVGAYPFEDPD+P Sbjct: 147 SKSSLLHSKPKSTVGTPAYIAPEVLSRREYDGKMADVWSCGVTLYVMLVGAYPFEDPDDP 206 Query: 182 KNFRKTITRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPI 361 KNFRKTI RI+S+QY +P+YV IS +CR LLSRIFVANP +RITI+EI+NHPWF+KNLP Sbjct: 207 KNFRKTIGRIVSIQYKIPEYVHISQDCRQLLSRIFVANPAKRITIREIRNHPWFMKNLPR 266 Query: 362 EMTDEYQMSLHMVGVNA---PPQSLEEIMAIIQEARIPGDGS 478 E+T+ Q + +A Q+++EIM I+QEA+ P S Sbjct: 267 ELTEAAQAKYYKKDNSARTFSDQTVDEIMKIVQEAKTPPPSS 308
>SAPK9_ORYSA (Q75V57) Serine/threonine-protein kinase SAPK9 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 9) Length = 361 Score = 235 bits (599), Expect = 9e-62 Identities = 112/170 (65%), Positives = 133/170 (78%) Frame = +2 Query: 2 SKSSVLHSQPKSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEP 181 SKSSVLHSQPKSTVGTPAYIAPEVL ++EYDGK+ADVWSCGVTLYVMLVGAYPFEDP++P Sbjct: 165 SKSSVLHSQPKSTVGTPAYIAPEVLLKKEYDGKIADVWSCGVTLYVMLVGAYPFEDPEDP 224 Query: 182 KNFRKTITRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPI 361 KNFRKTI +IL VQYS+PDYV IS ECR L++RIFV NP RIT+ EIKNHPWF+KN+P Sbjct: 225 KNFRKTIQKILGVQYSIPDYVHISPECRDLITRIFVGNPASRITMPEIKNHPWFMKNIPA 284 Query: 362 EMTDEYQMSLHMVGVNAPPQSLEEIMAIIQEARIPGDGSKFAGQLSVPGL 511 ++ D+ +S + P Q++ EIM I+ EA IP G+ Q L Sbjct: 285 DLMDDGMVSNQYEEPDQPMQNMNEIMQILAEATIPAAGTSGINQFLTDSL 334
>ASK2_ARATH (P43292) Serine/threonine-protein kinase ASK2 (EC 2.7.11.1)| Length = 353 Score = 233 bits (595), Expect = 3e-61 Identities = 111/155 (71%), Positives = 131/155 (84%) Frame = +2 Query: 2 SKSSVLHSQPKSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEP 181 SKSS+LHS+PKSTVGTPAYIAPEVLSRREYDGK ADVWSCGVTLYVMLVGAYPFEDP++P Sbjct: 147 SKSSILHSRPKSTVGTPAYIAPEVLSRREYDGKHADVWSCGVTLYVMLVGAYPFEDPNDP 206 Query: 182 KNFRKTITRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPI 361 KNFRKTI RI++VQY +PDYV IS EC+HLLSRIFV N +RIT++EIKNHPW+LKNLP Sbjct: 207 KNFRKTIQRIMAVQYKIPDYVHISQECKHLLSRIFVTNSAKRITLKEIKNHPWYLKNLPK 266 Query: 362 EMTDEYQMSLHMVGVNAPPQSLEEIMAIIQEARIP 466 E+ + Q + + + QS+E+IM I+ EAR P Sbjct: 267 ELLESAQAAYYKRDTSFSLQSVEDIMKIVGEARNP 301
>SAPK5_ORYSA (Q7XKA8) Serine/threonine-protein kinase SAPK5 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 5) Length = 370 Score = 228 bits (580), Expect = 1e-59 Identities = 113/168 (67%), Positives = 132/168 (78%), Gaps = 15/168 (8%) Frame = +2 Query: 2 SKSSVLHSQPKSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEP 181 SKSS+LHS+PKSTVGTPAYIAPEVLSRREYDGK+ADVWSCGVTLYVMLVGAYPFEDP +P Sbjct: 147 SKSSLLHSRPKSTVGTPAYIAPEVLSRREYDGKLADVWSCGVTLYVMLVGAYPFEDPKDP 206 Query: 182 KNFRKTITRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPI 361 KNFRKTI+RI+SVQY +P+YV +S CRHLLSRIFVANP +RI++ EIK+HPWFLKNLP Sbjct: 207 KNFRKTISRIMSVQYKIPEYVHVSQPCRHLLSRIFVANPYKRISMGEIKSHPWFLKNLPR 266 Query: 362 EMTDEYQ---------------MSLHMVGVNAPPQSLEEIMAIIQEAR 460 E+ +E Q S PQS+E+IM I+QEA+ Sbjct: 267 ELKEEAQAVYYNRRGADHAASSASSAAAAAAFSPQSVEDIMRIVQEAQ 314
>SAPK8_ORYSA (Q7Y0B9) Serine/threonine-protein kinase SAPK8 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 8) Length = 371 Score = 227 bits (578), Expect = 2e-59 Identities = 109/155 (70%), Positives = 129/155 (83%) Frame = +2 Query: 2 SKSSVLHSQPKSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEP 181 SKSSVLHSQPKSTVGTPAYIAPEVL ++EYDGK ADVWSCGVTLYVM+VGAYPFEDP+EP Sbjct: 176 SKSSVLHSQPKSTVGTPAYIAPEVLLKKEYDGKTADVWSCGVTLYVMVVGAYPFEDPEEP 235 Query: 182 KNFRKTITRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPI 361 KNFRKTI RIL+VQYS+P+ V IS ECRHL+SRIFV +P RITI EI++H WFLKNLP Sbjct: 236 KNFRKTIQRILNVQYSIPENVDISPECRHLISRIFVGDPSLRITIPEIRSHGWFLKNLPA 295 Query: 362 EMTDEYQMSLHMVGVNAPPQSLEEIMAIIQEARIP 466 ++ D+ MS + P Q++++IM I+ EA IP Sbjct: 296 DLMDDDSMSSQYEEPDQPMQTMDQIMQILTEATIP 330
>SAPK4_ORYSA (Q5N942) Serine/threonine-protein kinase SAPK4 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 4) Length = 360 Score = 225 bits (574), Expect = 7e-59 Identities = 111/156 (71%), Positives = 129/156 (82%), Gaps = 3/156 (1%) Frame = +2 Query: 2 SKSSVLHSQPKSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEP 181 SKSSVLHS+PKS VGTPAYIAPEVLSRREYDGK+ADVWSCGVTLYVMLVGAYPFED D+P Sbjct: 147 SKSSVLHSRPKSAVGTPAYIAPEVLSRREYDGKLADVWSCGVTLYVMLVGAYPFEDQDDP 206 Query: 182 KNFRKTITRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPI 361 KN RKTI RI+SVQY +PDYV IS EC+ L++RIFV NP +RIT++EIK+HPWFLKNLP Sbjct: 207 KNIRKTIQRIMSVQYKIPDYVHISAECKQLIARIFVNNPLRRITMKEIKSHPWFLKNLPR 266 Query: 362 EMTDEYQMSLHMVGVNAP---PQSLEEIMAIIQEAR 460 E+T+ Q + + P Q+ EEIM I+QEAR Sbjct: 267 ELTETAQAMYYRRDNSVPSFSDQTSEEIMKIVQEAR 302
>ASK1_ARATH (P43291) Serine/threonine-protein kinase ASK1 (EC 2.7.11.1)| Length = 363 Score = 220 bits (561), Expect = 2e-57 Identities = 111/175 (63%), Positives = 134/175 (76%), Gaps = 1/175 (0%) Frame = +2 Query: 2 SKSSVLHSQPKSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEP 181 SKSS+LHS+PKSTVGTPAYIAPEVLSRREYDGK+ADVWSCGVTLYVMLVGAYPFED ++P Sbjct: 147 SKSSLLHSRPKSTVGTPAYIAPEVLSRREYDGKMADVWSCGVTLYVMLVGAYPFEDQEDP 206 Query: 182 KNFRKTITRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPI 361 KNFRKTI +I++VQY +PDYV IS +C++LLSRIFVAN +RITI EIK H WFLKNLP Sbjct: 207 KNFRKTIQKIMAVQYKIPDYVHISQDCKNLLSRIFVANSLKRITIAEIKKHSWFLKNLPR 266 Query: 362 EMTDEYQMS-LHMVGVNAPPQSLEEIMAIIQEARIPGDGSKFAGQLSVPGLGSME 523 E+T+ Q + Q++EEIM I+ +A+ P S+ G G G + Sbjct: 267 ELTETAQAAYFKKENPTFSLQTVEEIMKIVADAKTPPPVSRSIGGFGWGGNGDAD 321
>CPK24_ARATH (Q9LDI3) CBL-interacting serine/threonine-protein kinase 24 (EC| 2.7.11.1) (SNF1-related kinase 3.11) (SALT OVERLY SENSITIVE 2 protein) Length = 446 Score = 102 bits (255), Expect = 7e-22 Identities = 55/121 (45%), Positives = 76/121 (62%), Gaps = 1/121 (0%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 ++T GTP Y+APEVLS + YDG AD+WSCGV L+V+L G PF + D P +RK I Sbjct: 167 RTTCGTPNYVAPEVLSGQGYDGSAADIWSCGVILFVILAGYLPFSETDLPGLYRK----I 222 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWF-LKNLPIEMTDEYQMS 388 + ++S P + S E + L+ RI NP+ RI IQ IK PWF L +PI +E +++ Sbjct: 223 NAAEFSCPPW--FSAEVKFLIHRILDPNPKTRIQIQGIKKDPWFRLNYVPIRAREEEEVN 280 Query: 389 L 391 L Sbjct: 281 L 281
>SNF1_SCHPO (O74536) SNF1-like protein kinase ssp2 (EC 2.7.11.1)| Length = 576 Score = 102 bits (254), Expect = 9e-22 Identities = 53/109 (48%), Positives = 71/109 (65%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 K++ G+P Y APEV++ + Y G DVWSCG+ LYVMLVG PF+D P F+K + Sbjct: 188 KTSCGSPNYAAPEVINGKLYAGPEVDVWSCGIVLYVMLVGRLPFDDEFIPNLFKK----V 243 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLP 358 S Y +PD+ +S + L+ R+ VA+P QRITIQEI+ PWF NLP Sbjct: 244 NSCVYVMPDF--LSPGAQSLIRRMIVADPMQRITIQEIRRDPWFNVNLP 290
>KIN10_ARATH (Q38997) SNF1-related protein kinase catalytic alpha subunit KIN10| (EC 2.7.11.1) (AKIN10) (AKIN alpha2) Length = 535 Score = 95.5 bits (236), Expect = 1e-19 Identities = 48/109 (44%), Positives = 68/109 (62%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 K++ G+P Y APEV+S + Y G DVWSCGV LY +L G PF+D + P F+K I Sbjct: 197 KTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDENIPNLFKK----I 252 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLP 358 Y++P + +S R L+ R+ V +P +R+TI EI+ HPWF +LP Sbjct: 253 KGGIYTLPSH--LSPGARDLIPRMLVVDPMKRVTIPEIRQHPWFQAHLP 299
>KIN11_ARATH (P92958) SNF1-related protein kinase catalytic alpha subunit KIN11| (EC 2.7.11.1) (AKIN11) (AKIN alpha1) Length = 512 Score = 95.1 bits (235), Expect = 1e-19 Identities = 48/109 (44%), Positives = 68/109 (62%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 K++ G+P Y APEV+S + Y G DVWSCGV LY +L G PF+D + P F+K I Sbjct: 175 KTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDENIPNLFKK----I 230 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLP 358 Y++P + +S E R L+ R+ + +P +RITI EI+ H WF +LP Sbjct: 231 KGGIYTLPSH--LSSEARDLIPRMLIVDPVKRITIPEIRQHRWFQTHLP 277
>CIPK1_ORYSA (Q6X4A2) CIPK-like protein 1 (EC 2.7.11.1) (OsCK1)| Length = 449 Score = 94.7 bits (234), Expect = 2e-19 Identities = 50/114 (43%), Positives = 64/114 (56%) Frame = +2 Query: 35 STVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRIL 214 +T GTP Y+APEV+ R YDG AD+WSCGV LYV+L G PFED N +I Sbjct: 179 TTCGTPNYVAPEVIEDRGYDGAAADIWSCGVILYVLLAGFLPFED----DNIIALYKKIS 234 Query: 215 SVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPIEMTDE 376 Q++ P + S + L++RI NP RITI +I PWF K + DE Sbjct: 235 EAQFTCPSW--FSTGAKKLITRILDPNPTTRITISQILEDPWFKKGYKPPVFDE 286
>CPK11_ARATH (O22932) CBL-interacting serine/threonine-protein kinase 11 (EC| 2.7.11.1) (SOS2-like protein kinase PKS5) (SOS-interacting protein 4) (SNF1-related kinase 3.22) Length = 435 Score = 94.0 bits (232), Expect = 3e-19 Identities = 44/102 (43%), Positives = 65/102 (63%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GTPAY+APE+LS++ Y+G DVWSCG+ L+V++ G PF DP+ ++K I + Sbjct: 184 GTPAYVAPEILSKKGYEGAKVDVWSCGIVLFVLVAGYLPFNDPNVMNMYKK----IYKGE 239 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLK 349 Y P + +S + + +SR+ NPE RITI EI PWF++ Sbjct: 240 YRFPRW--MSPDLKRFVSRLLDINPETRITIDEILKDPWFVR 279
>SNF1_CANTR (O94168) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 619 Score = 93.2 bits (230), Expect = 6e-19 Identities = 50/109 (45%), Positives = 68/109 (62%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 K++ G+P Y APEV+S + Y G DVWS GV LYVML G PF+D P F+K I Sbjct: 206 KTSCGSPNYAAPEVISGKLYAGPEVDVWSSGVILYVMLCGRLPFDDEFIPALFKK----I 261 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLP 358 + Y++P+Y +S +HLL+R+ V NP RITI EI WF +++P Sbjct: 262 SNGVYTLPNY--LSPGAKHLLTRMLVVNPLNRITIHEIMEDEWFKQDMP 308
>RKIN1_SECCE (Q02723) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 502 Score = 91.3 bits (225), Expect = 2e-18 Identities = 52/119 (43%), Positives = 71/119 (59%), Gaps = 2/119 (1%) Frame = +2 Query: 8 SSVLHSQP--KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEP 181 S+V+H K++ G+ Y APEV+S + Y G DVWSCGV LY +L GA PF+D + P Sbjct: 162 SNVMHDGHFLKTSCGSLNYAAPEVISGKLYAGPEIDVWSCGVILYALLCGAVPFDDDNIP 221 Query: 182 KNFRKTITRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLP 358 F+K I Y +P Y +S R L+SR+ + +P +RITI EI+ H WF LP Sbjct: 222 NLFKK----IKGGTYILPIY--LSDLVRDLISRMLIVDPMKRITIGEIRKHSWFQNRLP 274
>SN1L2_HUMAN (Q9H0K1) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Qin-induced kinase) Length = 926 Score = 90.5 bits (223), Expect = 4e-18 Identities = 42/107 (39%), Positives = 66/107 (61%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 G+P Y APEV ++Y+G D+WS GV LYV++ GA PF+ P P R+L + Sbjct: 178 GSPPYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLP----ILRQRVLEGR 233 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPIE 364 + +P + +S +C HL+ R+ V +P +R+TI +IK H W L +P++ Sbjct: 234 FRIPYF--MSEDCEHLIRRMLVLDPSKRLTIAQIKEHKWMLIEVPVQ 278
>SN1L2_PONPY (Q5REX1) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) Length = 925 Score = 90.5 bits (223), Expect = 4e-18 Identities = 42/107 (39%), Positives = 66/107 (61%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 G+P Y APEV ++Y+G D+WS GV LYV++ GA PF+ P P R+L + Sbjct: 178 GSPPYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLP----ILRQRVLEGR 233 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPIE 364 + +P + +S +C HL+ R+ V +P +R+TI +IK H W L +P++ Sbjct: 234 FRIPYF--MSEDCEHLIRRMLVLDPSKRLTIAQIKEHKWMLIEVPVQ 278
>KKK1_YEAST (P34244) Probable serine/threonine-protein kinase YKL101W (EC| 2.7.11.1) Length = 1518 Score = 90.5 bits (223), Expect = 4e-18 Identities = 46/112 (41%), Positives = 69/112 (61%), Gaps = 2/112 (1%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 K++ G+P Y +PE++ R Y G +DVWSCG+ L+ +L G PF D N +K + ++ Sbjct: 272 KTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPFND----DNIKKLLLKV 327 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLK--NLPI 361 S +Y +P +S E R L+S+I V +PE+RIT QEI HP K +LP+ Sbjct: 328 QSGKYQMPS--NLSSEARDLISKILVIDPEKRITTQEILKHPLIKKYDDLPV 377
>SNF1_CANAL (P52497) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 620 Score = 90.1 bits (222), Expect = 5e-18 Identities = 50/110 (45%), Positives = 69/110 (62%), Gaps = 1/110 (0%) Frame = +2 Query: 32 KSTVGTPAYI-APEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITR 208 K++ G+P Y+ APEV+S + Y G DVWS GV LYVML G PF+D P F+K Sbjct: 207 KTSCGSPNYMPAPEVISGKLYAGPEVDVWSAGVILYVMLCGRLPFDDEFIPALFKK---- 262 Query: 209 ILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLP 358 I + Y++P+Y +S +HLL+R+ V NP RITI EI WF +++P Sbjct: 263 ISNGVYTLPNY--LSAGAKHLLTRMLVVNPLNRITIHEIMEDDWFKQDMP 310
>SN1L2_MOUSE (Q8CFH6) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Salt-inducible kinase 2) Length = 931 Score = 89.0 bits (219), Expect = 1e-17 Identities = 41/107 (38%), Positives = 66/107 (61%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 G+P Y APEV ++Y+G D+WS GV LYV++ GA PF+ P P R+L + Sbjct: 178 GSPPYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLP----ILRQRVLEGR 233 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPIE 364 + +P + +S +C HL+ R+ V +P +R++I +IK H W L +P++ Sbjct: 234 FRIPYF--MSEDCEHLIRRMLVLDPSKRLSIAQIKEHKWMLIEVPVQ 278
>BRSK1_HUMAN (Q8TDC3) BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1| kinase) (SAD1A) Length = 794 Score = 89.0 bits (219), Expect = 1e-17 Identities = 39/105 (37%), Positives = 68/105 (64%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 +++ G+P Y PEV+ +YDG+ AD+WSCGV L+ +LVGA PF+D N R+ + ++ Sbjct: 204 ETSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGALPFDD----DNLRQLLEKV 259 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFL 346 + +P + I +C+ LL + PE+R+++++I+ HPW+L Sbjct: 260 KRGVFHMPHF--IPPDCQSLLRGMIEVEPEKRLSLEQIQKHPWYL 302
>CPK15_ARATH (P92937) CBL-interacting serine/threonine-protein kinase 15 (EC| 2.7.11.1) (Serine/threonine-protein kinase ATPK10) (SOS2-like protein kinase PKS3) (SOS-interacting protein 2) (SNF1-related kinase 3.1) Length = 421 Score = 89.0 bits (219), Expect = 1e-17 Identities = 46/116 (39%), Positives = 66/116 (56%) Frame = +2 Query: 35 STVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRIL 214 +T GTPAY+APEV+SR YDG ADVWSCGV L+V+L G PF D N + +I Sbjct: 170 TTCGTPAYVAPEVISRNGYDGFKADVWSCGVILFVLLAGYLPFRD----SNLMELYKKIG 225 Query: 215 SVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPIEMTDEYQ 382 + P++ ++ + LL RI NP R++ ++I WF K L E+ + + Sbjct: 226 KAEVKFPNW--LAPGAKRLLKRILDPNPNTRVSTEKIMKSSWFRKGLQEEVKESVE 279
>SN1L2_CHICK (Q9IA88) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Qin-induced kinase) Length = 798 Score = 88.2 bits (217), Expect = 2e-17 Identities = 49/143 (34%), Positives = 80/143 (55%), Gaps = 1/143 (0%) Frame = +2 Query: 26 QPKST-VGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTI 202 +P ST G+P Y APEV +EY+G D+WS GV LYV++ G+ PF+ P+ P R+ Sbjct: 177 EPLSTWCGSPPYAAPEVFEGKEYEGPHLDIWSLGVVLYVLVCGSLPFDGPNLP-TLRQ-- 233 Query: 203 TRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPIEMTDEYQ 382 R+L ++ +P + +S +C L+ R+ V +P +RITI +IK H W + + Sbjct: 234 -RVLEGRFRIPYF--MSEDCETLIRRMLVVDPTKRITISQIKQHKWMQADPSLRQQQSLS 290 Query: 383 MSLHMVGVNAPPQSLEEIMAIIQ 451 S+ N + E+++ I+Q Sbjct: 291 FSMQNYNSNLGDYN-EQVLGIMQ 312
>SN1L1_MOUSE (Q60670) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (HRT-20) (Myocardial SNF1-like kinase) Length = 779 Score = 87.8 bits (216), Expect = 2e-17 Identities = 50/143 (34%), Positives = 82/143 (57%), Gaps = 1/143 (0%) Frame = +2 Query: 26 QPKST-VGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTI 202 +P ST VG+P Y APEV +EY+G DVWS GV LYV++ G+ PF+ P+ P R+ Sbjct: 178 EPLSTCVGSPPYAAPEVFEGKEYEGPQLDVWSLGVVLYVLVCGSLPFDGPNLP-TLRQ-- 234 Query: 203 TRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPIEMTDEYQ 382 R+L ++ +P + +S +C L+ R+ V +P +RITI +I+ H W + + D+ Sbjct: 235 -RVLEGRFRIPFF--MSQDCETLIRRMLVVDPAKRITIAQIRQHRWMQADPTLLQQDDPA 291 Query: 383 MSLHMVGVNAPPQSLEEIMAIIQ 451 + N + E+++ I+Q Sbjct: 292 FDMQGYTSNLGDYN-EQVLGIMQ 313
>IPL1_ASHGO (Q755C4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 367 Score = 87.8 bits (216), Expect = 2e-17 Identities = 47/112 (41%), Positives = 68/112 (60%) Frame = +2 Query: 23 SQPKSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTI 202 S+ K+ GT Y++PE++ REY+ KV DVW+ GV Y +LVG+ PFE+ + ++ Sbjct: 261 SKRKTLCGTVDYLSPELIRSREYNEKV-DVWALGVLTYELLVGSPPFEEESKELTYK--- 316 Query: 203 TRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLP 358 RIL PD+V E RHL+SR+ +P RI ++E+K HPW KN P Sbjct: 317 -RILKRNLIFPDHV--DTEARHLISRLLEYDPGDRIPLKEVKKHPWIEKNKP 365
>SNRK_HUMAN (Q9NRH2) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 765 Score = 87.8 bits (216), Expect = 2e-17 Identities = 50/139 (35%), Positives = 84/139 (60%) Frame = +2 Query: 35 STVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRIL 214 ++ G+ AY APE+L EYD D+WS GV L++++ G PF++ N +T+T I+ Sbjct: 173 TSCGSLAYSAPEILLGDEYDAPAVDIWSLGVILFMLVCGQPPFQE----ANDSETLTMIM 228 Query: 215 SVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPIEMTDEYQMSLH 394 +Y+VP +V S EC+ L++R+ +P++R +++EI+NHPW L+ + +Y + L Sbjct: 229 DCKYTVPSHV--SKECKDLITRMLQRDPKRRASLEEIENHPW-LQGVDPSPATKYNIPL- 284 Query: 395 MVGVNAPPQSLEEIMAIIQ 451 V+ S EE +IIQ Sbjct: 285 ---VSYKNLSEEEHNSIIQ 300
>DUN1_YEAST (P39009) DNA damage response protein kinase DUN1 (EC 2.7.11.1)| Length = 513 Score = 87.4 bits (215), Expect = 3e-17 Identities = 45/100 (45%), Positives = 61/100 (61%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GTP+Y+APEVL+++ Y KV D+WS GV LYV L G PF D P + ++ I + Sbjct: 383 GTPSYVAPEVLTKKGYTSKV-DLWSAGVILYVCLCGFPPFSDQLGPPSLKEQILQAKYAF 441 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWF 343 YS P + +I HL+S + V NP++R I E NHPWF Sbjct: 442 YS-PYWDKIDDSVLHLISNLLVLNPDERYNIDEALNHPWF 480
>KCC4_YEAST (P25389) Probable serine/threonine-protein kinase KCC4 (EC| 2.7.11.1) Length = 1037 Score = 87.0 bits (214), Expect = 4e-17 Identities = 45/130 (34%), Positives = 75/130 (57%), Gaps = 11/130 (8%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 +++ G+P Y APE++S Y+G +DVWSCGV L+ +L G PF+ +E N R + ++ Sbjct: 184 ETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFD--EENGNVRDLLLKV 241 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWF-----------LKNLP 358 Q+ +P+ IS + + L+ +I V +P QRI I++I +HP +K+LP Sbjct: 242 QKGQFEMPNDTEISRDAQDLIGKILVVDPRQRIKIRDILSHPLLKKYQTIKDSKSIKDLP 301 Query: 359 IEMTDEYQMS 388 E T Y ++ Sbjct: 302 RENTYLYPLA 311
>SN1L1_RAT (Q9R1U5) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (Salt-inducible protein kinase) (Protein kinase KID2) Length = 776 Score = 87.0 bits (214), Expect = 4e-17 Identities = 49/143 (34%), Positives = 82/143 (57%), Gaps = 1/143 (0%) Frame = +2 Query: 26 QPKST-VGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTI 202 +P ST G+P Y APEV +EY+G D+WS GV LYV++ G+ PF+ P+ P R+ Sbjct: 178 EPLSTWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVVLYVLVCGSLPFDGPNLP-TLRQ-- 234 Query: 203 TRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPIEMTDEYQ 382 R+L ++ +P + +S +C L+ R+ V +P +RITI +I+ H W + + D+ Sbjct: 235 -RVLEGRFRIPFF--MSQDCETLIRRMLVVDPAKRITIAQIRQHRWMQADPTLLQQDDPA 291 Query: 383 MSLHMVGVNAPPQSLEEIMAIIQ 451 S+ N + E+++ I+Q Sbjct: 292 FSMQGYTSNLGDYN-EQVLGIMQ 313
>TRIB2_BOVIN (Q5GLH2) Tribbles homolog 2 (TRB-2)| Length = 343 Score = 85.9 bits (211), Expect = 9e-17 Identities = 45/101 (44%), Positives = 60/101 (59%), Gaps = 1/101 (0%) Frame = +2 Query: 44 GTPAYIAPEVLSRR-EYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSV 220 G PAY++PE+L+ Y GK ADVWS GV LY MLVG YPF D + F K I Sbjct: 214 GCPAYVSPEILNTNGSYSGKAADVWSLGVMLYTMLVGRYPFHDIEPSSLFSK----IRRG 269 Query: 221 QYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWF 343 Q+++P+ + +C L+ I P +R+T QEI +HPWF Sbjct: 270 QFNIPETLSPKAKC--LIRSILRREPSERLTSQEILDHPWF 308
>TRIB2_PONPY (Q5R669) Tribbles homolog 2 (TRB-2)| Length = 343 Score = 85.5 bits (210), Expect = 1e-16 Identities = 45/101 (44%), Positives = 60/101 (59%), Gaps = 1/101 (0%) Frame = +2 Query: 44 GTPAYIAPEVLSRR-EYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSV 220 G PAY++PE+L+ Y GK ADVWS GV LY MLVG YPF D + F K I Sbjct: 214 GCPAYVSPEILNTSGSYSGKAADVWSLGVMLYTMLVGRYPFHDIEPSSLFSK----IRRG 269 Query: 221 QYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWF 343 Q+++P+ + +C L+ I P +R+T QEI +HPWF Sbjct: 270 QFNIPETLSPKAKC--LIRSILRREPSERLTSQEILDHPWF 308
>TRIB2_MOUSE (Q8K4K3) Tribbles homolog 2 (TRB-2)| Length = 343 Score = 85.5 bits (210), Expect = 1e-16 Identities = 45/101 (44%), Positives = 60/101 (59%), Gaps = 1/101 (0%) Frame = +2 Query: 44 GTPAYIAPEVLSRR-EYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSV 220 G PAY++PE+L+ Y GK ADVWS GV LY MLVG YPF D + F K I Sbjct: 214 GCPAYVSPEILNTSGSYSGKAADVWSLGVMLYTMLVGRYPFHDIEPSSLFSK----IRRG 269 Query: 221 QYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWF 343 Q+++P+ + +C L+ I P +R+T QEI +HPWF Sbjct: 270 QFNIPETLSPKAKC--LIRSILRREPSERLTSQEILDHPWF 308
>TRIB2_HUMAN (Q92519) Tribbles homolog 2 (TRB-2)| Length = 343 Score = 85.5 bits (210), Expect = 1e-16 Identities = 45/101 (44%), Positives = 60/101 (59%), Gaps = 1/101 (0%) Frame = +2 Query: 44 GTPAYIAPEVLSRR-EYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSV 220 G PAY++PE+L+ Y GK ADVWS GV LY MLVG YPF D + F K I Sbjct: 214 GCPAYVSPEILNTSGSYSGKAADVWSLGVMLYTMLVGRYPFHDIEPSSLFSK----IRRG 269 Query: 221 QYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWF 343 Q+++P+ + +C L+ I P +R+T QEI +HPWF Sbjct: 270 QFNIPETLSPKAKC--LIRSILRREPSERLTSQEILDHPWF 308
>TRIB2_CANFA (Q28283) Tribbles homolog 2 (TRB-2)| Length = 343 Score = 85.5 bits (210), Expect = 1e-16 Identities = 45/101 (44%), Positives = 60/101 (59%), Gaps = 1/101 (0%) Frame = +2 Query: 44 GTPAYIAPEVLSRR-EYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSV 220 G PAY++PE+L+ Y GK ADVWS GV LY MLVG YPF D + F K I Sbjct: 214 GCPAYVSPEILNTSGSYSGKAADVWSLGVMLYTMLVGRYPFHDIEPSSLFSK----IRRG 269 Query: 221 QYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWF 343 Q+++P+ + +C L+ I P +R+T QEI +HPWF Sbjct: 270 QFNIPETLSPKAKC--LIRSILRREPSERLTSQEILDHPWF 308
>AAPK2_RAT (Q09137) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 85.5 bits (210), Expect = 1e-16 Identities = 43/109 (39%), Positives = 65/109 (59%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 +++ G+P Y APEV+S R Y G D+WSCGV LY +L G PF+D P F+K I Sbjct: 171 RTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKK----I 226 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLP 358 + +P+Y+ S+ LL + +P +R TI++I+ H WF ++LP Sbjct: 227 RGGVFYIPEYLNRSIAT--LLMHMLQVDPLKRATIKDIREHEWFKQDLP 273
>AAPK2_PONPY (Q5RD00) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 85.5 bits (210), Expect = 1e-16 Identities = 43/109 (39%), Positives = 65/109 (59%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 +++ G+P Y APEV+S R Y G D+WSCGV LY +L G PF+D P F+K I Sbjct: 171 RTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKK----I 226 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLP 358 + +P+Y+ S+ LL + +P +R TI++I+ H WF ++LP Sbjct: 227 RGGVFYIPEYLNRSVAT--LLMHMLQVDPLKRATIKDIREHEWFKQDLP 273
>AAPK2_PIG (Q28948) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 85.5 bits (210), Expect = 1e-16 Identities = 43/109 (39%), Positives = 65/109 (59%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 +++ G+P Y APEV+S R Y G D+WSCGV LY +L G PF+D P F+K I Sbjct: 171 RTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKK----I 226 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLP 358 + +P+Y+ S+ LL + +P +R TI++I+ H WF ++LP Sbjct: 227 RGGVFYIPEYLNRSVAT--LLMHMLQVDPLKRATIKDIREHEWFKQDLP 273
>AAPK2_HUMAN (P54646) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 85.5 bits (210), Expect = 1e-16 Identities = 43/109 (39%), Positives = 65/109 (59%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 +++ G+P Y APEV+S R Y G D+WSCGV LY +L G PF+D P F+K I Sbjct: 171 RTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKK----I 226 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLP 358 + +P+Y+ S+ LL + +P +R TI++I+ H WF ++LP Sbjct: 227 RGGVFYIPEYLNRSVAT--LLMHMLQVDPLKRATIKDIREHEWFKQDLP 273
>SN1L1_HUMAN (P57059) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) Length = 783 Score = 85.1 bits (209), Expect = 2e-16 Identities = 43/106 (40%), Positives = 67/106 (63%), Gaps = 1/106 (0%) Frame = +2 Query: 26 QPKST-VGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTI 202 +P ST G+P Y APEV +EY+G D+WS GV LYV++ G+ PF+ P+ P R+ Sbjct: 178 EPLSTWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVVLYVLVCGSLPFDGPNLP-TLRQ-- 234 Query: 203 TRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 R+L ++ +P + +S +C L+ R+ V +P +RITI +I+ H W Sbjct: 235 -RVLEGRFRIPFF--MSQDCESLIRRMLVVDPARRITIAQIRQHRW 277
>SNRK_RAT (Q63553) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 746 Score = 84.7 bits (208), Expect = 2e-16 Identities = 49/139 (35%), Positives = 83/139 (59%) Frame = +2 Query: 35 STVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRIL 214 ++ G+ AY APE+L EYD D+WS GV L++++ G PF++ N +T+T I+ Sbjct: 173 TSCGSLAYSAPEILLGDEYDAPAVDIWSLGVILFMLVCGQPPFQE----ANDSETLTMIM 228 Query: 215 SVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPIEMTDEYQMSLH 394 +Y+VP R+S CR L++R+ +P++R +++EI++HPW L+ + +Y + L Sbjct: 229 DCKYTVPP--RVSAGCRDLITRMLQRDPKRRASLEEIESHPW-LQGVDPSPATKYNIPL- 284 Query: 395 MVGVNAPPQSLEEIMAIIQ 451 V+ S EE +IIQ Sbjct: 285 ---VSYKNLSEEEHNSIIQ 300
>SNRK_MOUSE (Q8VDU5) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 748 Score = 84.7 bits (208), Expect = 2e-16 Identities = 49/139 (35%), Positives = 83/139 (59%) Frame = +2 Query: 35 STVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRIL 214 ++ G+ AY APE+L EYD D+WS GV L++++ G PF++ N +T+T I+ Sbjct: 173 TSCGSLAYSAPEILLGDEYDAPAVDIWSLGVILFMLVCGQPPFQE----ANDSETLTMIM 228 Query: 215 SVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPIEMTDEYQMSLH 394 +Y+VP R+S CR L++R+ +P++R +++EI++HPW L+ + +Y + L Sbjct: 229 DCKYTVPP--RVSAGCRDLITRMLQRDPKRRASLEEIESHPW-LQGVDPSPATKYNIPL- 284 Query: 395 MVGVNAPPQSLEEIMAIIQ 451 V+ S EE +IIQ Sbjct: 285 ---VSYKNLSEEEHNSIIQ 300
>AAPK2_CAEEL (Q95ZQ4) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMP-activated kinase 2) Length = 626 Score = 84.7 bits (208), Expect = 2e-16 Identities = 44/109 (40%), Positives = 63/109 (57%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 +++ G+P Y APEV+S + Y G DVWSCGV LY +L G PF+D P FRK I Sbjct: 242 RTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDEHVPSLFRK----I 297 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLP 358 S + PD+ + +LL + +P +R TI+++ H WF K+LP Sbjct: 298 KSGVFPTPDF--LERPIVNLLHHMLCVDPMKRATIKDVIAHEWFQKDLP 344
>KCC2A_DROME (Q00168) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) Length = 530 Score = 84.3 bits (207), Expect = 3e-16 Identities = 38/99 (38%), Positives = 62/99 (62%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GTP Y++PEVL + Y GK D+W+CGV LY++LVG PF D D+ + + + + + Sbjct: 176 GTPGYLSPEVLKKEPY-GKSVDIWACGVILYILLVGYPPFWDEDQHRLYSQ--IKAGAYD 232 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 Y P++ ++ E ++L++++ NP +RIT E HPW Sbjct: 233 YPSPEWDTVTPEAKNLINQMLTVNPNKRITAAEALKHPW 271
>KCC2B_HUMAN (Q13554) Calcium/calmodulin-dependent protein kinase type II beta| chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II beta subunit) (CaMK-II beta subunit) Length = 664 Score = 84.0 bits (206), Expect = 3e-16 Identities = 38/99 (38%), Positives = 63/99 (63%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GTP Y++PEVL + Y GK D+W+CGV LY++LVG PF D D+ K +++ + + Sbjct: 176 GTPGYLSPEVLRKEAY-GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQ--IKAGAYD 232 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 + P++ ++ E ++L++++ NP +RIT E HPW Sbjct: 233 FPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPW 271
>KCC2B_RAT (P08413) Calcium/calmodulin-dependent protein kinase type II beta| chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II beta subunit) (CaMK-II beta subunit) Length = 542 Score = 84.0 bits (206), Expect = 3e-16 Identities = 38/99 (38%), Positives = 63/99 (63%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GTP Y++PEVL + Y GK D+W+CGV LY++LVG PF D D+ K +++ + + Sbjct: 176 GTPGYLSPEVLRKEAY-GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQ--IKAGAYD 232 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 + P++ ++ E ++L++++ NP +RIT E HPW Sbjct: 233 FPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPW 271
>KCC2B_MOUSE (P28652) Calcium/calmodulin-dependent protein kinase type II beta| chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II beta subunit) (CaMK-II beta subunit) Length = 542 Score = 84.0 bits (206), Expect = 3e-16 Identities = 38/99 (38%), Positives = 63/99 (63%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GTP Y++PEVL + Y GK D+W+CGV LY++LVG PF D D+ K +++ + + Sbjct: 176 GTPGYLSPEVLRKEAY-GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQ--IKAGAYD 232 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 + P++ ++ E ++L++++ NP +RIT E HPW Sbjct: 233 FPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPW 271
>TRIB1_HUMAN (Q96RU8) Tribbles homolog 1 (TRB-1) (SKIP1) (G-protein-coupled| receptor induced protein 2) (GIG-2) Length = 372 Score = 83.6 bits (205), Expect = 4e-16 Identities = 45/101 (44%), Positives = 59/101 (58%), Gaps = 1/101 (0%) Frame = +2 Query: 44 GTPAYIAPEVLSRR-EYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSV 220 G PAY++PE+L+ Y GK ADVWS GV LY +LVG YPF D D F K I Sbjct: 244 GCPAYVSPEILNTTGTYSGKAADVWSLGVMLYTLLVGRYPFHDSDPSALFSK----IRRG 299 Query: 221 QYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWF 343 Q+ +P++ IS + R L+ + P +R+T EI HPWF Sbjct: 300 QFCIPEH--ISPKARCLIRSLLRREPSERLTAPEILLHPWF 338
>AAPK1_CAEEL (P45894) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMP-activated kinase 1) Length = 589 Score = 82.8 bits (203), Expect = 8e-16 Identities = 48/137 (35%), Positives = 74/137 (54%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 G+P Y APE++S + Y G D+WSCGV LY ML G PF+D + P F K I S + Sbjct: 183 GSPNYAAPELISNKLYVGPEVDLWSCGVILYAMLCGTLPFDDQNVPTLFAK----IKSGR 238 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPIEMTDEYQMSLHMVG 403 Y+VP + + L+S + +P +R ++ I NH WF +LP + E + +V Sbjct: 239 YTVP--YSMEKQAADLISTMLQVDPVKRADVKRIVNHSWFRIDLPYYLFPECENESSIVD 296 Query: 404 VNAPPQSLEEIMAIIQE 454 ++ QS+ E + +E Sbjct: 297 IDV-VQSVAEKFDVKEE 312
>KCC2A_MOUSE (P11798) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 82.8 bits (203), Expect = 8e-16 Identities = 38/99 (38%), Positives = 62/99 (62%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GTP Y++PEVL + Y GK D+W+CGV LY++LVG PF D D+ + +++ R + Sbjct: 175 GTPGYLSPEVLRKDPY-GKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAR--AYD 231 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 + P++ ++ E + L++++ NP +RIT E HPW Sbjct: 232 FPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPW 270
>TRIB1_MOUSE (Q8K4K4) Tribbles homolog 1 (TRB-1)| Length = 372 Score = 82.4 bits (202), Expect = 1e-15 Identities = 44/101 (43%), Positives = 59/101 (58%), Gaps = 1/101 (0%) Frame = +2 Query: 44 GTPAYIAPEVLSRR-EYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSV 220 G PAY++PE+L+ Y GK ADVWS GV LY +LVG YPF D D F K I Sbjct: 244 GCPAYVSPEILNTTGTYSGKAADVWSLGVMLYTLLVGRYPFHDSDPSALFSK----IRRG 299 Query: 221 QYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWF 343 Q+ +P++V S + R L+ + P +R+T +I HPWF Sbjct: 300 QFCIPEHV--SPKARCLIRSLLRREPSERLTAPQILLHPWF 338
>SNF1_YEAST (P06782) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 633 Score = 82.0 bits (201), Expect = 1e-15 Identities = 45/109 (41%), Positives = 62/109 (56%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 K++ G+P Y APEV+S + Y G DVWSCGV LYVML PF+D P F+ I Sbjct: 209 KTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRLPFDDESIPVLFK----NI 264 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLP 358 + Y++P + +S L+ R+ + NP RI+I EI WF +LP Sbjct: 265 SNGVYTLPKF--LSPGAAGLIKRMLIVNPLNRISIHEIMQDDWFKVDLP 311
>KCC2G_HUMAN (Q13555) Calcium/calmodulin-dependent protein kinase type II gamma| chain (EC 2.7.11.17) (CaM-kinase II gamma chain) (CaM kinase II gamma subunit) (CaMK-II gamma subunit) Length = 558 Score = 82.0 bits (201), Expect = 1e-15 Identities = 37/99 (37%), Positives = 63/99 (63%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GTP Y++PEVL + Y GK D+W+CGV LY++LVG PF D D+ K +++ + + Sbjct: 176 GTPGYLSPEVLRKDPY-GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQ--IKAGAYD 232 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 + P++ ++ E ++L++++ NP +RIT + HPW Sbjct: 233 FPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPW 271
>KCC2G_RAT (P11730) Calcium/calmodulin-dependent protein kinase type II gamma| chain (EC 2.7.11.17) (CaM-kinase II gamma chain) (CaM kinase II gamma subunit) (CaMK-II gamma subunit) Length = 527 Score = 82.0 bits (201), Expect = 1e-15 Identities = 37/99 (37%), Positives = 63/99 (63%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GTP Y++PEVL + Y GK D+W+CGV LY++LVG PF D D+ K +++ + + Sbjct: 176 GTPGYLSPEVLRKDPY-GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQ--IKAGAYD 232 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 + P++ ++ E ++L++++ NP +RIT + HPW Sbjct: 233 FPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPW 271
>KCC2G_MOUSE (Q923T9) Calcium/calmodulin-dependent protein kinase type II gamma| chain (EC 2.7.11.17) (CaM-kinase II gamma chain) (CaM kinase II gamma subunit) (CaMK-II gamma subunit) Length = 529 Score = 82.0 bits (201), Expect = 1e-15 Identities = 37/99 (37%), Positives = 63/99 (63%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GTP Y++PEVL + Y GK D+W+CGV LY++LVG PF D D+ K +++ + + Sbjct: 176 GTPGYLSPEVLRKDPY-GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQ--IKAGAYD 232 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 + P++ ++ E ++L++++ NP +RIT + HPW Sbjct: 233 FPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPW 271
>CIPK1_ARATH (Q8RWC9) CBL-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (SOS2-like protein kinase PKS13) (SNF1-related kinase 3.16) Length = 444 Score = 81.6 bits (200), Expect = 2e-15 Identities = 42/103 (40%), Positives = 59/103 (57%) Frame = +2 Query: 35 STVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRIL 214 +T G+P Y+APEVL+ R YDG +D+WSCGV LYV+L G PF+D +N +I Sbjct: 179 TTCGSPNYVAPEVLANRGYDGAASDIWSCGVILYVILTGCLPFDD----RNLAVLYQKIC 234 Query: 215 SVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWF 343 +P + +S R ++ R+ NP RIT+ IK WF Sbjct: 235 KGDPPIPRW--LSPGARTMIKRMLDPNPVTRITVVGIKASEWF 275
>KKCC2_RAT (O88831) Calcium/calmodulin-dependent protein kinase kinase 2 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta) Length = 587 Score = 81.6 bits (200), Expect = 2e-15 Identities = 47/118 (39%), Positives = 67/118 (56%), Gaps = 4/118 (3%) Frame = +2 Query: 35 STVGTPAYIAPEVLS--RREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITR 208 +TVGTPA++APE LS R+ + GK DVW+ GVTLY + G PF D + ++ Sbjct: 345 NTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMD----ERIMCLHSK 400 Query: 209 ILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKN--LPIEMTDE 376 I S PD I+ + + L++R+ NPE RI + EIK HPW ++ P+ DE Sbjct: 401 IKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWVTRHGAEPLPSEDE 458
>IPL1_CANGA (Q6FV07) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 358 Score = 81.6 bits (200), Expect = 2e-15 Identities = 42/112 (37%), Positives = 69/112 (61%) Frame = +2 Query: 23 SQPKSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTI 202 S+ K+ GT Y++PE+++ REYD +V DVW+ GV Y ++VG PFE+ + ++ Sbjct: 252 SKRKTLCGTIDYLSPEMITPREYDEQV-DVWALGVLAYELVVGVPPFEENSKELTYK--- 307 Query: 203 TRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLP 358 RIL + P+ IS + + L+S++ V + QR+++ +K HPW LKN P Sbjct: 308 -RILKCDLNFPE--SISKDAKDLISKLLVTDTTQRLSLTGVKTHPWILKNKP 356
>KKCC2_MOUSE (Q8C078) Calcium/calmodulin-dependent protein kinase kinase 2 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta) Length = 588 Score = 81.6 bits (200), Expect = 2e-15 Identities = 47/118 (39%), Positives = 67/118 (56%), Gaps = 4/118 (3%) Frame = +2 Query: 35 STVGTPAYIAPEVLS--RREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITR 208 +TVGTPA++APE LS R+ + GK DVW+ GVTLY + G PF D + ++ Sbjct: 346 NTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMD----ERIMCLHSK 401 Query: 209 ILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKN--LPIEMTDE 376 I S PD I+ + + L++R+ NPE RI + EIK HPW ++ P+ DE Sbjct: 402 IKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWVTRHGAEPLPSEDE 459
>KKCC2_HUMAN (Q96RR4) Calcium/calmodulin-dependent protein kinase kinase 2 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta) Length = 588 Score = 81.6 bits (200), Expect = 2e-15 Identities = 47/118 (39%), Positives = 67/118 (56%), Gaps = 4/118 (3%) Frame = +2 Query: 35 STVGTPAYIAPEVLS--RREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITR 208 +TVGTPA++APE LS R+ + GK DVW+ GVTLY + G PF D + ++ Sbjct: 346 NTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMD----ERIMCLHSK 401 Query: 209 ILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKN--LPIEMTDE 376 I S PD I+ + + L++R+ NPE RI + EIK HPW ++ P+ DE Sbjct: 402 IKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWVTRHGAEPLPSEDE 459
>BRSK2_HUMAN (Q8IWQ3) BR serine/threonine-protein kinase 2 (EC 2.7.11.1)| (Serine/threonine-protein kinase 29) (SAD1B) Length = 736 Score = 81.3 bits (199), Expect = 2e-15 Identities = 40/111 (36%), Positives = 68/111 (61%), Gaps = 2/111 (1%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 +++ G+P Y PEV+ +YDG+ ADVWSCGV L+ +LVGA PF+D N R+ + ++ Sbjct: 173 ETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDD----DNLRQLLEKV 228 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFL--KNLP 358 + +P + I +C+ LL + + +R+T++ I+ H W++ KN P Sbjct: 229 KRGVFHMPHF--IPPDCQSLLRGMSEVDAARRLTLEHIQKHIWYIGGKNEP 277
>KCC2D_HUMAN (Q13557) Calcium/calmodulin-dependent protein kinase type II delta| chain (EC 2.7.11.17) (CaM-kinase II delta chain) (CaM kinase II delta subunit) (CaMK-II delta subunit) Length = 499 Score = 80.9 bits (198), Expect = 3e-15 Identities = 37/99 (37%), Positives = 62/99 (62%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GTP Y++PEVL + Y GK D+W+CGV LY++LVG PF D D+ + +++ + + Sbjct: 176 GTPGYLSPEVLRKDPY-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQ--IKAGAYD 232 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 + P++ ++ E + L++++ NP +RIT E HPW Sbjct: 233 FPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPW 271
>KIN1_SCHPO (P22987) Protein kinase kin1 (EC 2.7.11.1)| Length = 891 Score = 80.9 bits (198), Expect = 3e-15 Identities = 40/110 (36%), Positives = 65/110 (59%) Frame = +2 Query: 23 SQPKSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTI 202 S+ ++ G+ + APE+L+ + Y G DVWS G+ LYV++ G PF+D +N Sbjct: 295 SRLRTFCGSLYFAAPELLNAQPYIGPEVDVWSFGIVLYVLVCGKVPFDD----QNMSALH 350 Query: 203 TRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKN 352 +I P Y +S +C+ LLSR+ V +P +R T++E+ NHPW ++N Sbjct: 351 AKIKKGTVEYPSY--LSSDCKGLLSRMLVTDPLKRATLEEVLNHPWMIRN 398
>KCC2A_RAT (P11275) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 80.9 bits (198), Expect = 3e-15 Identities = 37/99 (37%), Positives = 62/99 (62%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GTP Y++PEVL + Y GK D+W+CGV LY++LVG PF D D+ + +++ + + Sbjct: 175 GTPGYLSPEVLRKDPY-GKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQ--IKAGAYD 231 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 + P++ ++ E + L++++ NP +RIT E HPW Sbjct: 232 FPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPW 270
>KCC2A_PONPY (Q5RCC4) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 80.9 bits (198), Expect = 3e-15 Identities = 37/99 (37%), Positives = 62/99 (62%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GTP Y++PEVL + Y GK D+W+CGV LY++LVG PF D D+ + +++ + + Sbjct: 175 GTPGYLSPEVLRKDPY-GKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQ--IKAGAYD 231 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 + P++ ++ E + L++++ NP +RIT E HPW Sbjct: 232 FPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPW 270
>KCC2A_HUMAN (Q9UQM7) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 80.9 bits (198), Expect = 3e-15 Identities = 37/99 (37%), Positives = 62/99 (62%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GTP Y++PEVL + Y GK D+W+CGV LY++LVG PF D D+ + +++ + + Sbjct: 175 GTPGYLSPEVLRKDPY-GKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQ--IKAGAYD 231 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 + P++ ++ E + L++++ NP +RIT E HPW Sbjct: 232 FPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPW 270
>GIN4_YEAST (Q12263) Serine/threonine-protein kinase GIN4 (EC 2.7.11.1)| Length = 1142 Score = 80.9 bits (198), Expect = 3e-15 Identities = 38/106 (35%), Positives = 62/106 (58%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 +++ G+P Y APE++S Y G +DVWSCGV L+ +L G PF++ D N R + ++ Sbjct: 188 ETSCGSPHYAAPEIVSGIPYQGFASDVWSCGVILFALLTGRLPFDEED--GNIRTLLLKV 245 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLK 349 ++ +P IS E + L+ +I +PE+RI ++I HP K Sbjct: 246 QKGEFEMPSDDEISREAQDLIRKILTVDPERRIKTRDILKHPLLQK 291
>KCC2D_RAT (P15791) Calcium/calmodulin-dependent protein kinase type II delta| chain (EC 2.7.11.17) (CaM-kinase II delta chain) (CaM kinase II delta subunit) (CaMK-II delta subunit) Length = 533 Score = 80.9 bits (198), Expect = 3e-15 Identities = 37/99 (37%), Positives = 62/99 (62%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GTP Y++PEVL + Y GK D+W+CGV LY++LVG PF D D+ + +++ + + Sbjct: 176 GTPGYLSPEVLRKDPY-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQ--IKAGAYD 232 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 + P++ ++ E + L++++ NP +RIT E HPW Sbjct: 233 FPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPW 271
>AAPK1_PONPY (Q5RDH5) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 550 Score = 80.5 bits (197), Expect = 4e-15 Identities = 42/109 (38%), Positives = 62/109 (56%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 +++ G+P Y APEV+S R Y G D+WS GV LY +L G PF+D P F+K I Sbjct: 173 RTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGI 232 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLP 358 + P Y+ S+ LL + +P +R TI++I+ H WF ++LP Sbjct: 233 ----FYTPQYLNPSV--ISLLKHMLQVDPMKRATIKDIREHEWFKQDLP 275
>AAPK1_HUMAN (Q13131) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 550 Score = 80.5 bits (197), Expect = 4e-15 Identities = 42/109 (38%), Positives = 62/109 (56%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 +++ G+P Y APEV+S R Y G D+WS GV LY +L G PF+D P F+K I Sbjct: 173 RTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGI 232 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLP 358 + P Y+ S+ LL + +P +R TI++I+ H WF ++LP Sbjct: 233 ----FYTPQYLNPSV--ISLLKHMLQVDPMKRATIKDIREHEWFKQDLP 275
>CDR2_SCHPO (P87050) Mitosis inducer protein kinase cdr2 (EC 2.7.11.1)| Length = 775 Score = 80.5 bits (197), Expect = 4e-15 Identities = 35/103 (33%), Positives = 62/103 (60%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 +++ G+P Y +PE++ R YDG +D+WSCG+ + +L G PF+D N R + ++ Sbjct: 165 QTSCGSPHYASPEIIMGRSYDGCASDIWSCGIIFFALLTGKLPFDD----DNIRSLLLKV 220 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 Q+ +P IS + +HLL R+ + RIT+++I+ HP+ Sbjct: 221 CQGQFEMPS--NISPQAQHLLYRMLDVDSSTRITMEQIREHPF 261
>AAPK1_RAT (P54645) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 548 Score = 80.5 bits (197), Expect = 4e-15 Identities = 42/109 (38%), Positives = 62/109 (56%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 +++ G+P Y APEV+S R Y G D+WS GV LY +L G PF+D P F+K I Sbjct: 171 RTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGI 230 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLP 358 + P Y+ S+ LL + +P +R TI++I+ H WF ++LP Sbjct: 231 ----FYTPQYLNPSV--ISLLKHMLQVDPMKRATIKDIREHEWFKQDLP 273
>SNF1_CANGA (Q00372) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 612 Score = 79.7 bits (195), Expect = 6e-15 Identities = 44/108 (40%), Positives = 61/108 (56%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 K++ G+P Y APEV+S + Y G DVWSCGV LYVML PF+D P F+ I Sbjct: 193 KTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRLPFDDESIPVLFK----NI 248 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNL 355 + Y++P + +S L+ R+ + NP RI+I EI WF +L Sbjct: 249 SNGVYTLPKF--LSPGASDLIKRMLIVNPLNRISIHEIMQDEWFKVDL 294
>KIN4_YEAST (Q01919) Serine/threonine-protein kinase KIN4 (EC 2.7.11.1)| Length = 800 Score = 79.7 bits (195), Expect = 6e-15 Identities = 45/107 (42%), Positives = 60/107 (56%), Gaps = 4/107 (3%) Frame = +2 Query: 32 KSTVGTPAYIAPE-VLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDE---PKNFRKT 199 K++ G+P Y APE V+S + Y+ + ADVWSCGV LY ML G P++D E + + Sbjct: 208 KTSCGSPCYAAPELVVSTKAYEARKADVWSCGVILYAMLAGYLPWDDDHENPTGDDIARL 267 Query: 200 ITRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 I P+Y I+ R LL RI V NP +RI +Q IK H W Sbjct: 268 YKYITQTPLKFPEY--ITPIPRDLLRRILVPNPRRRINLQTIKRHVW 312
>MARK4_MOUSE (Q8CIP4) MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1)| Length = 752 Score = 78.6 bits (192), Expect = 1e-14 Identities = 40/113 (35%), Positives = 62/113 (54%) Frame = +2 Query: 2 SKSSVLHSQPKSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEP 181 S L S+ + G+P Y APE+ ++YDG D+WS GV LY ++ G+ PF+ Sbjct: 203 SNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFDG---- 258 Query: 182 KNFRKTITRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 N ++ R+L +Y VP Y +S +C +L R V NP +R T+++I W Sbjct: 259 HNLKELRERVLRGKYRVPFY--MSTDCESILRRFLVLNPAKRCTLEQIMKDKW 309
>MARK4_HUMAN (Q96L34) MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase-like 1) Length = 752 Score = 78.6 bits (192), Expect = 1e-14 Identities = 40/113 (35%), Positives = 62/113 (54%) Frame = +2 Query: 2 SKSSVLHSQPKSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEP 181 S L S+ + G+P Y APE+ ++YDG D+WS GV LY ++ G+ PF+ Sbjct: 203 SNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFDG---- 258 Query: 182 KNFRKTITRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 N ++ R+L +Y VP Y +S +C +L R V NP +R T+++I W Sbjct: 259 HNLKELRERVLRGKYRVPFY--MSTDCESILRRFLVLNPAKRCTLEQIMKDKW 309
>MARK3_RAT (Q8VHF0) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| Length = 797 Score = 78.6 bits (192), Expect = 1e-14 Identities = 45/144 (31%), Positives = 80/144 (55%), Gaps = 11/144 (7%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 G+P Y APE+ ++YDG DVWS GV LY ++ G+ PF+ +N ++ R+L + Sbjct: 214 GSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDG----QNLKELRERVLRGK 269 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWF--------LKNL---PIEMT 370 Y +P Y +S +C +LL R V NP +R T+++I W LK ++++ Sbjct: 270 YRIPFY--MSTDCENLLKRFLVLNPVKRGTLEQIMKDRWINAGHEEEELKPFVEPELDIS 327 Query: 371 DEYQMSLHMVGVNAPPQSLEEIMA 442 D+ ++ + MVG+ + ++E ++ Sbjct: 328 DQKRIDI-MVGMGYSQEEIQESLS 350
>YP141_YEAST (Q03002) Putative serine/threonine-protein kinase YPL141C (EC| 2.7.11.1) Length = 865 Score = 78.6 bits (192), Expect = 1e-14 Identities = 43/107 (40%), Positives = 65/107 (60%), Gaps = 4/107 (3%) Frame = +2 Query: 32 KSTVGTPAYIAPE-VLSRREYDGKVADVWSCGVTLYVMLVGAYPF-EDPDEPK--NFRKT 199 K++ G+P Y APE V+S Y+ + AD+WSCGV LY +L G P+ +DP+ P+ + + Sbjct: 208 KTSCGSPCYAAPELVISAEPYEARKADIWSCGVILYAILAGYLPWDDDPNNPEGSDIGRL 267 Query: 200 ITRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 I S PDY I R LL R+ V++P++RI +++IK H W Sbjct: 268 YNYINSTPLKFPDY--ILPIPRDLLRRMLVSDPKKRINLKQIKKHEW 312
>MARK3_MOUSE (Q03141) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| (MPK-10) (ELKL motif kinase 2) Length = 753 Score = 78.6 bits (192), Expect = 1e-14 Identities = 45/144 (31%), Positives = 80/144 (55%), Gaps = 11/144 (7%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 G+P Y APE+ ++YDG DVWS GV LY ++ G+ PF+ +N ++ R+L + Sbjct: 214 GSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDG----QNLKELRERVLRGK 269 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWF--------LKNL---PIEMT 370 Y +P Y +S +C +LL R V NP +R T+++I W LK ++++ Sbjct: 270 YRIPFY--MSTDCENLLKRFLVLNPVKRGTLEQIMKDRWINAGHEEDELKPFVEPELDIS 327 Query: 371 DEYQMSLHMVGVNAPPQSLEEIMA 442 D+ ++ + MVG+ + ++E ++ Sbjct: 328 DQKRIDI-MVGMGYSQEEIQESLS 350
>AAPK1_MOUSE (Q5EG47) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 548 Score = 78.6 bits (192), Expect = 1e-14 Identities = 41/109 (37%), Positives = 61/109 (55%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 +++ G+P Y APEV+S R Y G D+WS GV LY +L G PF+D P F+K I Sbjct: 171 RTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGI 230 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLP 358 + P Y+ S+ LL + +P +R I++I+ H WF ++LP Sbjct: 231 ----FYTPQYLNPSV--ISLLKHMLQVDPMKRAAIKDIREHEWFKQDLP 273
>CSKP_MOUSE (O70589) Peripheral plasma membrane protein CASK (EC 2.7.11.1)| (Calcium/calmodulin-dependent serine protein kinase) Length = 924 Score = 78.6 bits (192), Expect = 1e-14 Identities = 45/145 (31%), Positives = 75/145 (51%), Gaps = 2/145 (1%) Frame = +2 Query: 41 VGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSV 220 VGTP ++APEV+ R Y GK DVW CGV L+++L G PF E + I+ Sbjct: 180 VGTPHFMAPEVVKREPY-GKPVDVWGCGVILFILLSGCLPFYGTKE-----RLFEGIIKG 233 Query: 221 QYSV--PDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPIEMTDEYQMSLH 394 +Y + + IS + L+ R+ + +P +RIT+ E NHPW ++ D Y +H Sbjct: 234 KYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPW------LKERDRYAYKIH 287 Query: 395 MVGVNAPPQSLEEIMAIIQEARIPG 469 + P+++E++ + ++ G Sbjct: 288 L------PETVEQLRKLNARRKLKG 306
>MARK3_HUMAN (P27448) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| (Cdc25C-associated protein kinase 1) (cTAK1) (C-TAK1) (Serine/threonine protein kinase p78) (Ser/Thr protein kinase PAR-1) (Protein kinase STK10) Length = 776 Score = 78.2 bits (191), Expect = 2e-14 Identities = 45/144 (31%), Positives = 80/144 (55%), Gaps = 11/144 (7%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 G+P Y APE+ ++YDG DVWS GV LY ++ G+ PF+ +N ++ R+L + Sbjct: 237 GSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDG----QNLKELRERVLRGK 292 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWF--------LKNL---PIEMT 370 Y +P Y +S +C +LL R V NP +R T+++I W LK ++++ Sbjct: 293 YRIPFY--MSTDCENLLKRFLVLNPIKRGTLEQIMKDRWINAGHEEDELKPFVEPELDIS 350 Query: 371 DEYQMSLHMVGVNAPPQSLEEIMA 442 D+ ++ + MVG+ + ++E ++ Sbjct: 351 DQKRIDI-MVGMGYSQEEIQESLS 373
>CSKP_HUMAN (O14936) Peripheral plasma membrane protein CASK (EC 2.7.11.1)| (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog) Length = 926 Score = 77.8 bits (190), Expect = 2e-14 Identities = 45/145 (31%), Positives = 74/145 (51%), Gaps = 2/145 (1%) Frame = +2 Query: 41 VGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSV 220 VGTP ++APEV+ R Y GK DVW CGV L+++L G PF E + I+ Sbjct: 180 VGTPHFMAPEVVKREPY-GKPVDVWGCGVILFILLSGCLPFYGTKE-----RLFEGIIKG 233 Query: 221 QYSV--PDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPIEMTDEYQMSLH 394 +Y + + IS + L+ R+ + +P +RIT+ E NHPW ++ D Y +H Sbjct: 234 KYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPW------LKERDRYAYKIH 287 Query: 395 MVGVNAPPQSLEEIMAIIQEARIPG 469 + P+++E++ ++ G Sbjct: 288 L------PETVEQLRKFNARRKLKG 306
>CSKP_RAT (Q62915) Peripheral plasma membrane protein CASK (EC 2.7.11.1)| (Calcium/calmodulin-dependent serine protein kinase) Length = 909 Score = 77.8 bits (190), Expect = 2e-14 Identities = 45/145 (31%), Positives = 74/145 (51%), Gaps = 2/145 (1%) Frame = +2 Query: 41 VGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSV 220 VGTP ++APEV+ R Y GK DVW CGV L+++L G PF E + I+ Sbjct: 180 VGTPHFMAPEVVKREPY-GKPVDVWGCGVILFILLSGCLPFYGTKE-----RLFEGIIKG 233 Query: 221 QYSV--PDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPIEMTDEYQMSLH 394 +Y + + IS + L+ R+ + +P +RIT+ E NHPW ++ D Y +H Sbjct: 234 KYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPW------LKERDRYAYKIH 287 Query: 395 MVGVNAPPQSLEEIMAIIQEARIPG 469 + P+++E++ ++ G Sbjct: 288 L------PETVEQLRKFNARRKLKG 306
>MARK2_RAT (O08679) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1) Length = 722 Score = 77.4 bits (189), Expect = 3e-14 Identities = 36/99 (36%), Positives = 59/99 (59%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 G+P Y APE+ ++YDG DVWS GV LY ++ G+ PF+ +N ++ R+L + Sbjct: 211 GSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDG----QNLKELRERVLRGK 266 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 Y +P Y +S +C +LL + + NP +R T+++I W Sbjct: 267 YRIPFY--MSTDCENLLKKFLILNPSKRGTLEQIMKDRW 303
>TSSK3_MOUSE (Q9D2E1) Testis-specific serine/threonine-protein kinase 3 (EC| 2.7.11.1) (TSSK-3) (Testis-specific kinase 3) (TSK-3) (Serine/threonine-protein kinase 22C) Length = 268 Score = 77.4 bits (189), Expect = 3e-14 Identities = 42/99 (42%), Positives = 56/99 (56%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 G+ AY APEVL +D K DVWS GV LYVML + PF+D D PK + + Sbjct: 171 GSTAYAAPEVLQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQKGV---- 226 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 S P ++ IS EC+ LL R+ + R +I+E+ HPW Sbjct: 227 -SFPTHLGISTECQDLLKRLLEPDMILRPSIEEVSWHPW 264
>MARK2_HUMAN (Q7KZI7) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog) Length = 788 Score = 77.4 bits (189), Expect = 3e-14 Identities = 36/99 (36%), Positives = 59/99 (59%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 G+P Y APE+ ++YDG DVWS GV LY ++ G+ PF+ +N ++ R+L + Sbjct: 211 GSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDG----QNLKELRERVLRGK 266 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 Y +P Y +S +C +LL + + NP +R T+++I W Sbjct: 267 YRIPFY--MSTDCENLLKKFLILNPSKRGTLEQIMKDRW 303
>MAPK2_HUMAN (P49137) MAP kinase-activated protein kinase 2 (EC 2.7.11.1)| (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAPK-2) (MK2) Length = 400 Score = 77.4 bits (189), Expect = 3e-14 Identities = 43/125 (34%), Positives = 64/125 (51%), Gaps = 2/125 (1%) Frame = +2 Query: 2 SKSSVLHSQPKSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEP 181 +K + H+ + TP Y+APEVL +YD K D+WS GV +Y++L G PF Sbjct: 211 AKETTSHNSLTTPCYTPYYVAPEVLGPEKYD-KSCDMWSLGVIMYILLCGYPPFYSNHGL 269 Query: 182 KNFRKTITRILSVQYSVP--DYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNL 355 TRI QY P ++ +S E + L+ + P QR+TI E NHPW +++ Sbjct: 270 AISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQST 329 Query: 356 PIEMT 370 + T Sbjct: 330 KVPQT 334
>SSP1_SCHPO (P50526) Serine/threonine-protein kinase ssp1 (EC 2.7.11.1)| Length = 652 Score = 77.4 bits (189), Expect = 3e-14 Identities = 49/111 (44%), Positives = 63/111 (56%), Gaps = 5/111 (4%) Frame = +2 Query: 38 TVGTPAYIAPEV----LSR-REYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTI 202 TVGTPA+ APE+ L R R + DVW+ GVTL+ +L G PF E + F K + Sbjct: 307 TVGTPAFFAPELCWTDLDRPRPKISEAIDVWALGVTLFCLLFGRCPFNASMEYELFDKIV 366 Query: 203 TRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNL 355 L++ S PD I E R LL R+ +PEQRIT+ E+K HPW L L Sbjct: 367 NERLNIP-STPD---IGEEGRDLLKRLLCKDPEQRITLVEVKLHPWTLDGL 413
>MAPK2_MOUSE (P49138) MAP kinase-activated protein kinase 2 (EC 2.7.11.1)| (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAPK-2) (MK2) Length = 386 Score = 77.4 bits (189), Expect = 3e-14 Identities = 43/125 (34%), Positives = 64/125 (51%), Gaps = 2/125 (1%) Frame = +2 Query: 2 SKSSVLHSQPKSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEP 181 +K + H+ + TP Y+APEVL +YD K D+WS GV +Y++L G PF Sbjct: 197 AKETTSHNSLTTPCYTPYYVAPEVLGPEKYD-KSCDMWSLGVIMYILLCGYPPFYSNHGL 255 Query: 182 KNFRKTITRILSVQYSVP--DYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNL 355 TRI QY P ++ +S E + L+ + P QR+TI E NHPW +++ Sbjct: 256 AISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQST 315 Query: 356 PIEMT 370 + T Sbjct: 316 KVPQT 320
>MAPK2_CRILO (P49136) MAP kinase-activated protein kinase 2 (EC 2.7.11.1)| (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAPK-2) (P45-54 HSP27 kinase) (Fragment) Length = 329 Score = 77.4 bits (189), Expect = 3e-14 Identities = 43/125 (34%), Positives = 64/125 (51%), Gaps = 2/125 (1%) Frame = +2 Query: 2 SKSSVLHSQPKSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEP 181 +K + H+ + TP Y+APEVL +YD K D+WS GV +Y++L G PF Sbjct: 140 AKETTSHNSLTTPCYTPYYVAPEVLGPEKYD-KSCDMWSLGVIMYILLCGYPPFYSNHGL 198 Query: 182 KNFRKTITRILSVQYSVP--DYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNL 355 TRI QY P ++ +S E + L+ + P QR+TI E NHPW +++ Sbjct: 199 AISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQST 258 Query: 356 PIEMT 370 + T Sbjct: 259 KVPQT 263
>STK6_XENLA (Q91820) Serine/threonine-protein kinase Eg2 (EC 2.7.11.1) (pEg2)| (p46Eg265) Length = 407 Score = 77.0 bits (188), Expect = 4e-14 Identities = 43/118 (36%), Positives = 64/118 (54%) Frame = +2 Query: 23 SQPKSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTI 202 S+ + GT Y+ PE++ R +D V D+WS GV Y LVG PFE + +R Sbjct: 291 SRRTTLCGTLDYLPPEMIEGRMHDETV-DLWSLGVLCYEFLVGKPPFETDTHQETYR--- 346 Query: 203 TRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPIEMTDE 376 RI V++ P YV S E R L+S++ NP R+ ++ + HPW +KN ++ DE Sbjct: 347 -RISKVEFQYPPYV--SEEARDLVSKLLKHNPNHRLPLKGVLEHPWIIKNSQLKKKDE 401
>KKCC1_HUMAN (Q8N5S9) Calcium/calmodulin-dependent protein kinase kinase 1 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-kinase kinase alpha) (CaM-KK alpha) (CaMKK alpha) (CaMKK 1) (CaM-kinase IV kinase) Length = 505 Score = 77.0 bits (188), Expect = 4e-14 Identities = 45/112 (40%), Positives = 61/112 (54%), Gaps = 2/112 (1%) Frame = +2 Query: 23 SQPKSTVGTPAYIAPEVLSR--REYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRK 196 +Q ST GTPA++APE +S + + GK DVW+ GVTLY + G PF D RK Sbjct: 305 AQLSSTAGTPAFMAPEAISDSGQSFSGKALDVWATGVTLYCFVYGKCPFIDDFILALHRK 364 Query: 197 TITRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKN 352 I + P+ IS E + L+ ++ NPE RI + +IK HPW KN Sbjct: 365 ----IKNEPVVFPEEPEISEELKDLILKMLDKNPETRIGVPDIKLHPWVTKN 412
>TSSK3_HUMAN (Q96PN8) Testis-specific serine/threonine-protein kinase 3 (EC| 2.7.11.1) (TSSK-3) (Testis-specific kinase 3) (TSK-3) (Serine/threonine-protein kinase 22C) Length = 268 Score = 76.6 bits (187), Expect = 5e-14 Identities = 41/99 (41%), Positives = 56/99 (56%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 G+ AY APEVL +D K DVWS GV LYVML + PF+D D PK + + Sbjct: 171 GSTAYAAPEVLQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQKGV---- 226 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 S P ++ IS +C+ LL R+ + R +I+E+ HPW Sbjct: 227 -SFPTHLSISADCQDLLKRLLEPDMILRPSIEEVSWHPW 264
>MARK1_MOUSE (Q8VHJ5) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) (ELKL motif serine/threonine-protein kinase 3) Length = 795 Score = 76.3 bits (186), Expect = 7e-14 Identities = 37/99 (37%), Positives = 60/99 (60%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 G+P Y APE+ ++YDG DVWS GV LY ++ G+ PF+ +N ++ R+L + Sbjct: 218 GSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDG----QNLKELRERVLRGK 273 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 Y VP Y +S +C +LL ++ V NP +R ++++I W Sbjct: 274 YRVPFY--MSTDCENLLKKLLVLNPIKRGSLEQIMKDRW 310
>MARK1_RAT (O08678) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) Length = 793 Score = 76.3 bits (186), Expect = 7e-14 Identities = 37/99 (37%), Positives = 60/99 (60%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 G+P Y APE+ ++YDG DVWS GV LY ++ G+ PF+ +N ++ R+L + Sbjct: 218 GSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDG----QNLKELRERVLRGK 273 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 Y VP Y +S +C +LL ++ V NP +R ++++I W Sbjct: 274 YRVPFY--MSTDCENLLKKLLVLNPIKRGSLEQIMKDRW 310
>KKCC1_MOUSE (Q8VBY2) Calcium/calmodulin-dependent protein kinase kinase 1 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-kinase kinase alpha) (CaM-KK alpha) (CaMKK alpha) (CaMKK 1) (CaM-kinase IV kinase) Length = 505 Score = 76.3 bits (186), Expect = 7e-14 Identities = 43/113 (38%), Positives = 65/113 (57%), Gaps = 3/113 (2%) Frame = +2 Query: 23 SQPKSTVGTPAYIAPEVLSR--REYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRK 196 +Q ST GTPA++APE +S + + GK DVW+ GVTLY + G PF D ++ Sbjct: 305 AQLSSTAGTPAFMAPEAISDSGQSFSGKALDVWATGVTLYCFVYGKCPFID-----DYIL 359 Query: 197 TITRILSVQYSV-PDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKN 352 T+ R + + V P+ +S + + L+ R+ NPE RI + +IK HPW K+ Sbjct: 360 TLHRKIKNEAVVFPEEPEVSEDLKDLILRMLDKNPETRIGVSDIKLHPWVTKH 412
>IPL1_DEBHA (Q6BVA0) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 412 Score = 75.9 bits (185), Expect = 9e-14 Identities = 38/103 (36%), Positives = 59/103 (57%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GT Y+ PE++ E+D V D+WS G+ Y LVG PFE+ D+ ++ RI V Sbjct: 309 GTLDYLPPEMIESNEHDYTV-DIWSLGILCYEFLVGKPPFEEIDKNSTYK----RIAKVD 363 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKN 352 +P + +S E L+ R+ +P++RIT+ E+ NHPW + N Sbjct: 364 LKIPSF--LSSEATDLILRLLQKSPKKRITLAEVMNHPWIMNN 404
>MARK1_HUMAN (Q9P0L2) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) Length = 795 Score = 75.9 bits (185), Expect = 9e-14 Identities = 36/99 (36%), Positives = 60/99 (60%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 G+P Y APE+ ++YDG DVWS GV LY ++ G+ PF+ +N ++ R+L + Sbjct: 218 GSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDG----QNLKELRERVLRGK 273 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 Y +P Y +S +C +LL ++ V NP +R ++++I W Sbjct: 274 YRIPFY--MSTDCENLLKKLLVLNPIKRGSLEQIMKDRW 310
>YP150_YEAST (Q12152) Putative serine/threonine-protein kinase YPL150W (EC| 2.7.11.1) Length = 901 Score = 75.9 bits (185), Expect = 9e-14 Identities = 42/120 (35%), Positives = 63/120 (52%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 ++ GT Y+APE++ RR YDG D+WS GV LY ++ G PF+D DE K K + Sbjct: 189 ETVCGTTVYMAPELIERRTYDGFKIDIWSLGVILYTLITGYLPFDDDDEAKTKWKIVNEE 248 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPIEMTDEYQMSL 391 V I + R L+SR+ NP +R ++ ++ HP FL+ + D+ Q L Sbjct: 249 PKYDAKV-----IPDDARDLISRLLAKNPGERPSLSQVLRHP-FLQPYGSVVLDQTQKIL 302
>ICL1_KLULA (Q6CWQ4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 361 Score = 75.5 bits (184), Expect = 1e-13 Identities = 40/107 (37%), Positives = 61/107 (57%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 K+ GT Y++PE++ REY+ KV DVW+ GV Y +LVG+ PFE+ + +R RI Sbjct: 255 KTLCGTIDYLSPELIKSREYNNKV-DVWALGVLTYELLVGSPPFEEDTKEMTYR----RI 309 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKN 352 L P + +S + R L+ R+ P +RI + E+K+H W N Sbjct: 310 LRCDLKFP--LNVSPQARDLIVRLLQFEPSKRIPLSEVKSHAWIANN 354
>KKCC1_RAT (P97756) Calcium/calmodulin-dependent protein kinase kinase 1 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-kinase kinase alpha) (CaM-KK alpha) (CaMKK alpha) (alpha CaMKK) (CaMKK 1) (CaM-kinase IV kinase) Length = 505 Score = 75.1 bits (183), Expect = 2e-13 Identities = 43/112 (38%), Positives = 61/112 (54%), Gaps = 2/112 (1%) Frame = +2 Query: 23 SQPKSTVGTPAYIAPEVLSR--REYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRK 196 +Q ST GTPA++APE +S + + GK DVW+ GVTLY + G PF D RK Sbjct: 305 AQLSSTAGTPAFMAPEAISDTGQSFSGKALDVWATGVTLYCFVYGKCPFIDEYILALHRK 364 Query: 197 TITRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKN 352 I + P+ +S E + L+ ++ NPE RI + +IK HPW K+ Sbjct: 365 ----IKNEAVVFPEEPEVSEELKDLILKMLDKNPETRIGVSDIKLHPWVTKH 412
>MELK_HUMAN (Q14680) Maternal embryonic leucine zipper kinase (EC 2.7.11.1)| (hMELK) (Protein kinase PK38) (hPK38) Length = 651 Score = 75.1 bits (183), Expect = 2e-13 Identities = 39/109 (35%), Positives = 66/109 (60%), Gaps = 2/109 (1%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 G+ AY APE++ + Y G ADVWS G+ LYV++ G PF+D + ++K I+ + Sbjct: 170 GSLAYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKK----IMRGK 225 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLK--NLPIE 364 Y VP + +S LL ++ +P++RI+++ + NHPW ++ N P+E Sbjct: 226 YDVPKW--LSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVE 272
>ARK1_SCHPO (O59790) Serine/threonine-protein kinase ark1 (EC 2.7.11.1)| (Aurora-related kinase 1) Length = 355 Score = 75.1 bits (183), Expect = 2e-13 Identities = 40/102 (39%), Positives = 59/102 (57%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GT Y+ PE++ +E+ KV D+WS GV Y LVGA PFED T RI V Sbjct: 247 GTLDYLPPEMVEGKEHTEKV-DLWSLGVLTYEFLVGAPPFEDMS---GHSATYKRIAKVD 302 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLK 349 +P +V + R L+SR+ NPE+R++++++ HPW +K Sbjct: 303 LKIPSFV--PPDARDLISRLLQHNPEKRMSLEQVMRHPWIVK 342
>PLK3_MOUSE (Q60806) Serine/threonine-protein kinase PLK3 (EC 2.7.11.21)| (Polo-like kinase 3) (PLK-3) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) Length = 631 Score = 74.7 bits (182), Expect = 2e-13 Identities = 43/106 (40%), Positives = 62/106 (58%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 K+ GTP Y+APEVL R+ + G ADVWS G +Y +L G+ PFE D ++T I Sbjct: 219 KTICGTPNYVAPEVLLRQGH-GPEADVWSLGCVMYTLLCGSPPFETAD----LKETYRCI 273 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLK 349 V Y++P +S+ R LL+ I A+P R +I++I H +F K Sbjct: 274 KQVHYTLP--ASLSLPARQLLAAILRASPRDRPSIEQILRHDFFTK 317
>PLK3_RAT (Q9R011) Serine/threonine-protein kinase PLK3 (EC 2.7.11.21)| (Polo-like kinase 3) (PLK-3) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) (Fragment) Length = 615 Score = 74.7 bits (182), Expect = 2e-13 Identities = 43/106 (40%), Positives = 62/106 (58%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 K+ GTP Y+APEVL R+ + G ADVWS G +Y +L G+ PFE D ++T I Sbjct: 187 KTICGTPNYVAPEVLLRQGH-GPEADVWSLGCVMYTLLCGSPPFETAD----LKETYRCI 241 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLK 349 V Y++P +S+ R LL+ I A+P R +I++I H +F K Sbjct: 242 KQVHYTLP--ASLSLPARQLLAAILRASPRDRPSIEQILRHDFFTK 285
>STK6_HUMAN (O14965) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1) (Aurora-related kinase 1) (hARK1) (Aurora-A) (Breast-tumor-amplified kinase) Length = 403 Score = 74.7 bits (182), Expect = 2e-13 Identities = 42/110 (38%), Positives = 62/110 (56%) Frame = +2 Query: 23 SQPKSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTI 202 S+ + GT Y+ PE++ R +D KV D+WS GV Y LVG PFE +++T Sbjct: 284 SRRTTLCGTLDYLPPEMIEGRMHDEKV-DLWSLGVLCYEFLVGKPPFE----ANTYQETY 338 Query: 203 TRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKN 352 RI V+++ PD+V + R L+SR+ NP QR ++E+ HPW N Sbjct: 339 KRISRVEFTFPDFV--TEGARDLISRLLKHNPSQRPMLREVLEHPWITAN 386
>STK6_MOUSE (P97477) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Aurora-family kinase 1) (Aurora/IPL1-related kinase 1) (Ipl1- and aurora-related kinase 1) (Aurora-A) (Serine/threonine-protein kinase Ayk1) Length = 395 Score = 74.3 bits (181), Expect = 3e-13 Identities = 42/110 (38%), Positives = 62/110 (56%) Frame = +2 Query: 23 SQPKSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTI 202 S+ + GT Y+ PE++ R +D KV D+WS GV Y LVG PFE +++T Sbjct: 275 SRRTTMCGTLDYLPPEMIEGRMHDEKV-DLWSLGVLCYEFLVGMPPFE----AHTYQETY 329 Query: 203 TRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKN 352 RI V+++ PD+V + R L+SR+ N QR+T+ E+ HPW N Sbjct: 330 RRISRVEFTFPDFV--TEGARDLISRLLKHNASQRLTLAEVLEHPWIKAN 377
>IPL1_YARLI (Q6C3J2) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 371 Score = 74.3 bits (181), Expect = 3e-13 Identities = 41/113 (36%), Positives = 63/113 (55%), Gaps = 1/113 (0%) Frame = +2 Query: 23 SQPKSTV-GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKT 199 S +ST+ GT Y+ PE++ R YD V DVWS G+ +Y L GA PFE EP + T Sbjct: 249 SNRRSTLCGTMDYLPPEIVQSRPYDKNV-DVWSLGILMYEFLCGAPPFE---EPGGAQAT 304 Query: 200 ITRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLP 358 RI+ + +P YV S + L+ R+ +P +R ++++ HPW ++ P Sbjct: 305 YRRIVKLDLRIPPYV--SADAADLIKRMLTLDPAKRFKLKDMHKHPWIVRLRP 355
>MARK2_MOUSE (Q05512) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1) Length = 776 Score = 74.3 bits (181), Expect = 3e-13 Identities = 35/99 (35%), Positives = 58/99 (58%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 G+P Y APE+ ++ DG DVWS GV LY ++ G+ PF+ +N ++ R+L + Sbjct: 211 GSPPYAAPELFQGKKIDGPEVDVWSLGVILYTLVSGSLPFDG----QNLKELRERVLRGK 266 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 Y +P Y +S +C +LL + + NP +R T+++I W Sbjct: 267 YRIPFY--MSTDCENLLKKFLILNPSKRGTLEQIMKDRW 303
>STK6L_XENLA (Q91819) Serine/threonine-protein kinase Eg2-like (EC 2.7.11.1)| (p46XlEg22) Length = 408 Score = 74.3 bits (181), Expect = 3e-13 Identities = 41/110 (37%), Positives = 61/110 (55%) Frame = +2 Query: 23 SQPKSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTI 202 S+ + GT Y+ PE++ R +D KV D+WS GV Y LVG PFE + +R Sbjct: 291 SRRTTLCGTLDYLPPEMIEGRMHDEKV-DLWSLGVLCYEFLVGKPPFETDTHQETYR--- 346 Query: 203 TRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKN 352 RI V++ P YV S E + L+S++ NP R+ ++ + HPW +KN Sbjct: 347 -RISKVEFQYPPYV--SEEAKDLVSKLLKHNPNHRLPLKGVLEHPWIVKN 393
>KPSH1_HUMAN (P11801) Serine/threonine-protein kinase H1 (EC 2.7.11.1) (PSK-H1)| Length = 423 Score = 73.9 bits (180), Expect = 4e-13 Identities = 38/103 (36%), Positives = 57/103 (55%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 K+T GTP YIAPEVL R+ Y V D+W+ GV Y++L G PFED + + +R+ + Sbjct: 254 KTTCGTPEYIAPEVLVRKPYTNSV-DMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGK 312 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 S YS + +S + + R+ +P R+T + HPW Sbjct: 313 YS--YSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPW 353
>PLK3_HUMAN (Q9H4B4) Serine/threonine-protein kinase PLK3 (EC 2.7.11.21)| (Polo-like kinase 3) (PLK-3) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) (Proliferation-related kinase) Length = 646 Score = 73.9 bits (180), Expect = 4e-13 Identities = 43/106 (40%), Positives = 61/106 (57%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 K+ GTP Y+APEVL R+ + G ADVWS G +Y +L G+ PFE D ++T I Sbjct: 218 KTICGTPNYVAPEVLLRQGH-GPEADVWSLGCVMYTLLCGSPPFETAD----LKETYRCI 272 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLK 349 V Y++P +S+ R LL+ I A+P R +I +I H +F K Sbjct: 273 KQVHYTLP--ASLSLPARQLLAAILRASPRDRPSIDQILRHDFFTK 316
>MAPK3_MOUSE (Q3UMW7) MAP kinase-activated protein kinase 3 (EC 2.7.11.1)| (MAPK-activated protein kinase 3) (MAPKAP kinase 3) (MAPKAPK-3) Length = 384 Score = 73.2 bits (178), Expect = 6e-13 Identities = 39/113 (34%), Positives = 61/113 (53%), Gaps = 2/113 (1%) Frame = +2 Query: 47 TPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQY 226 TP Y+APEVL +YD K D+WS GV +Y++L G PF RI QY Sbjct: 207 TPYYVAPEVLGPEKYD-KSCDMWSLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRLGQY 265 Query: 227 SVP--DYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPIEMTDEY 379 S P +++ +S + + L+ + +P +R+TI + NHPW +++ + T Y Sbjct: 266 SFPNPEWLDVSEDAKQLIRLLLKTDPTERLTIMQFMNHPWINQSMVVPQTPLY 318
>TSSK2_HUMAN (Q96PF2) Testis-specific serine/threonine-protein kinase 2 (EC| 2.7.11.1) (TSSK-2) (Testis-specific kinase 2) (TSK-2) (Serine/threonine-protein kinase 22B) (DiGeorge syndrome protein G) Length = 358 Score = 72.8 bits (177), Expect = 8e-13 Identities = 38/103 (36%), Positives = 56/103 (54%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 K+ G+ AY APEVL Y KV D+WS GV LY+M+ G+ P++D D RK + Sbjct: 173 KTFCGSAAYAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSD----IRKMLRIQ 228 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 + P ++ EC+ L+ R+ + QR+ I EI +H W Sbjct: 229 KEHRVDFPRSKNLTCECKDLIYRMLQPDVSQRLHIDEILSHSW 271
>MELK_MOUSE (Q61846) Maternal embryonic leucine zipper kinase (EC 2.7.11.1)| (Protein kinase PK38) (mPK38) Length = 643 Score = 72.8 bits (177), Expect = 8e-13 Identities = 38/109 (34%), Positives = 66/109 (60%), Gaps = 2/109 (1%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 G+ AY APE++ + Y G ADVWS G+ LYV++ G PF+D + ++K I+ + Sbjct: 170 GSLAYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKK----IMRGK 225 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLK--NLPIE 364 Y VP + +S LL ++ +P++RI+++ + NHPW ++ + P+E Sbjct: 226 YEVPKW--LSPSSILLLQQMLQVDPKKRISMRNLLNHPWVMQDYSCPVE 272
>STK6_RAT (P59241) Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Aurora-A)| (ratAurA) Length = 397 Score = 72.4 bits (176), Expect = 1e-12 Identities = 42/110 (38%), Positives = 61/110 (55%) Frame = +2 Query: 23 SQPKSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTI 202 S+ + GT Y PE++ R +D KV D+WS GV Y LVG PFE +++T Sbjct: 277 SRRTTLCGTLDYQPPEMIEGRMHDEKV-DLWSLGVLCYEFLVGMPPFE----AHTYQETY 331 Query: 203 TRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKN 352 RI V+++ PD+V + R L+SR+ N QR+T+ E+ HPW N Sbjct: 332 RRISRVEFTFPDFV--TEGARDLISRLLKHNSSQRLTLAEVLEHPWIKAN 379
>CAKI_DROME (Q24210) Calcium/calmodulin-dependent protein kinase (EC 2.7.11.17)| (CAKI) (Peripheral plasma membrane protein CaMGUK) Length = 898 Score = 72.4 bits (176), Expect = 1e-12 Identities = 38/100 (38%), Positives = 59/100 (59%) Frame = +2 Query: 41 VGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSV 220 VG P Y+APEV++RR Y GK DVW GV L+V+L G PF ++++ R + Sbjct: 182 VGCPHYMAPEVVTRRLY-GKGCDVWGAGVMLHVLLSGRLPFLGSGV--RLQQSVARG-RL 237 Query: 221 QYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 + P++ IS + L+ ++ ANP R++I E+ +HPW Sbjct: 238 SFEAPEWKSISANAKDLVMKMLAANPHHRLSITEVLDHPW 277
>KPSH1_BRARE (Q501V0) Serine/threonine-protein kinase H1 homolog (EC 2.7.11.1)| Length = 422 Score = 72.4 bits (176), Expect = 1e-12 Identities = 35/105 (33%), Positives = 59/105 (56%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 K+T GTP YIAPE+L R+ Y V D+W+ GV Y++L G PFED + + +R+ + Sbjct: 253 KTTCGTPEYIAPEILVRKPYTNAV-DMWALGVISYILLSGTMPFEDDNRMRLYRQILKGK 311 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFL 346 S +S + +S + + R+ +P +R++ + HPW + Sbjct: 312 YS--FSGEPWPSVSNLAKDFIDRVLTVDPNERLSAGQALKHPWIV 354
>CDPK_SOYBN (P28583) Calcium-dependent protein kinase SK5 (EC 2.7.11.1) (CDPK)| Length = 508 Score = 72.0 bits (175), Expect = 1e-12 Identities = 38/102 (37%), Positives = 58/102 (56%) Frame = +2 Query: 41 VGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSV 220 VG+P Y+APEVL R+ G +DVWS GV LY++L G PF EP FR+ + + + Sbjct: 196 VGSPYYVAPEVL--RKLYGPESDVWSAGVILYILLSGVPPFWAESEPGIFRQIL--LGKL 251 Query: 221 QYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFL 346 + + IS + L+ ++ NP+ R+T E+ HPW + Sbjct: 252 DFHSEPWPSISDSAKDLIRKMLDQNPKTRLTAHEVLRHPWIV 293
>MYLK_DICDI (P25323) Myosin light chain kinase (EC 2.7.11.18) (MLCK)| Length = 295 Score = 71.6 bits (174), Expect = 2e-12 Identities = 40/125 (32%), Positives = 63/125 (50%), Gaps = 2/125 (1%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 ++ GTP+Y+APEVL+ YD K D+WS GV Y++L G PF P+ F +I Sbjct: 165 QTACGTPSYVAPEVLNATGYD-KEVDMWSIGVITYILLCGFPPFYGDTVPEIFE----QI 219 Query: 212 LSVQYSVPD--YVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPIEMTDEYQM 385 + Y P+ + IS E + + ++ V + +R+ NHPW N D +M Sbjct: 220 MEANYEFPEEYWGGISKEAKDFIGKLLVVDVSKRLNATNALNHPWLKSNNSNNTIDTVKM 279 Query: 386 SLHMV 400 ++V Sbjct: 280 KEYIV 284
>PLK4_HUMAN (O00444) Serine/threonine-protein kinase PLK4 (EC 2.7.11.21)| (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine-protein kinase 18) Length = 970 Score = 71.6 bits (174), Expect = 2e-12 Identities = 37/118 (31%), Positives = 66/118 (55%) Frame = +2 Query: 20 HSQPKSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKT 199 H + + GTP YI+PE+ +R + G +DVWS G Y +L+G PF D D KN T Sbjct: 165 HEKHYTLCGTPNYISPEIATRSAH-GLESDVWSLGCMFYTLLIGRPPF-DTDTVKN---T 219 Query: 200 ITRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPIEMTD 373 + +++ Y +P + +S+E + L+ ++ NP R+++ + +HP+ +N + D Sbjct: 220 LNKVVLADYEMPTF--LSIEAKDLIHQLLRRNPADRLSLSSVLDHPFMSRNSSTKSKD 275
>KPSH1_MOUSE (Q91YA2) Serine/threonine-protein kinase H1 (EC 2.7.11.1) (PSK-H1)| Length = 423 Score = 71.6 bits (174), Expect = 2e-12 Identities = 37/103 (35%), Positives = 56/103 (54%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 K+T GTP YIAPEVL R+ Y V D+W+ GV Y++L G PFED + + +R+ + Sbjct: 254 KTTCGTPEYIAPEVLVRKPYTNSV-DMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGK 312 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 S Y + +S + + R+ +P R+T + HPW Sbjct: 313 YS--YLGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPW 353
>TRIB3_HUMAN (Q96RU7) Tribbles homolog 3 (TRB-3) (Neuronal cell death-inducible| putative kinase) (p65-interacting inhibitor of NF-kappaB) (SINK) Length = 358 Score = 70.9 bits (172), Expect = 3e-12 Identities = 43/109 (39%), Positives = 59/109 (54%), Gaps = 2/109 (1%) Frame = +2 Query: 50 PAYIAPEVLSRR-EYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQY 226 PAY+ PE+LS R Y GK ADVWS GV L+ ML G YPF+D + F K I Y Sbjct: 223 PAYVGPEILSSRASYSGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGK----IRRGAY 278 Query: 227 SVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKN-LPIEMT 370 ++P +S R L+ + P +R+T I HPW ++ +P+ T Sbjct: 279 ALP--AGLSAPARCLVRCLLRREPAERLTATGILLHPWLRQDPMPLAPT 325
>IPL1_YEAST (P38991) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) (Increase-in-ploidy protein 1) Length = 367 Score = 70.9 bits (172), Expect = 3e-12 Identities = 35/109 (32%), Positives = 63/109 (57%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 K+ GT Y++PE++ REYD + D W+ GV + +L GA PFE+ + ++ RI Sbjct: 259 KTVCGTIDYLSPEMVESREYDHTI-DAWALGVLAFELLTGAPPFEEEMKDTTYK----RI 313 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLP 358 ++ +P IS + + L+ ++ +P+ R+ + ++K HPW L+N P Sbjct: 314 AALDIKMPS--NISQDAQDLILKLLKYDPKDRMRLGDVKMHPWILRNKP 360
>KPSH1_PINFU (Q4KTY1) Serine/threonine-protein kinase H1 homolog (EC 2.7.11.1)| Length = 415 Score = 70.5 bits (171), Expect = 4e-12 Identities = 32/107 (29%), Positives = 62/107 (57%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 ++T GTP YIAPE+++R+ Y +V D+W+ GV Y++L G PF+D ++ + +R + Sbjct: 234 RTTCGTPEYIAPEIIARKPYMCQV-DMWAVGVITYILLSGTMPFDDENKTRLYRLILKAK 292 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKN 352 S Y+ + +S + + + ++ V +P R++ + H W + N Sbjct: 293 YS--YAGEHWKDVSAQAKDFIDKLLVVSPGDRLSAADALKHQWLISN 337
>CHK1_HUMAN (O14757) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 70.5 bits (171), Expect = 4e-12 Identities = 39/104 (37%), Positives = 56/104 (53%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GT Y+APE+L RRE+ + DVWSCG+ L ML G P+ D+P + + + + Sbjct: 169 GTLPYVAPELLKRREFHAEPVDVWSCGIVLTAMLAGELPW---DQPSDSCQEYSDWKEKK 225 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNL 355 + + +I LL +I V NP RITI +IK W+ K L Sbjct: 226 TYLNPWKKIDSAPLALLHKILVENPSARITIPDIKKDRWYNKPL 269
>KPCT_HUMAN (Q04759) Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)| Length = 706 Score = 70.5 bits (171), Expect = 4e-12 Identities = 42/102 (41%), Positives = 60/102 (58%), Gaps = 2/102 (1%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GTP YIAPE+L ++Y+ V D WS GV LY ML+G PF DE + F S++ Sbjct: 541 GTPDYIAPEILLGQKYNHSV-DWWSFGVLLYEMLIGQSPFHGQDEEELFH-------SIR 592 Query: 224 YSVPDYVR-ISMECRHLLSRIFVANPEQRITIQ-EIKNHPWF 343 P Y R + E + LL ++FV PE+R+ ++ +I+ HP F Sbjct: 593 MDNPFYPRWLEKEAKDLLVKLFVREPEKRLGVRGDIRQHPLF 634
>MAPK3_RAT (Q66H84) MAP kinase-activated protein kinase 3 (EC 2.7.11.1)| (MAPK-activated protein kinase 3) (MAPKAP kinase 3) (MAPKAPK-3) Length = 384 Score = 70.5 bits (171), Expect = 4e-12 Identities = 37/110 (33%), Positives = 58/110 (52%), Gaps = 2/110 (1%) Frame = +2 Query: 47 TPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQY 226 TP Y+APEVL +YD K D+WS GV +Y++L G PF RI QY Sbjct: 207 TPYYVAPEVLGPEKYD-KSCDMWSLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRLGQY 265 Query: 227 SVP--DYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPIEMT 370 P ++ +S + + L+ + +P +R+TI + NHPW +++ + T Sbjct: 266 GFPKPEWADVSEDAKQLIRLLLKTDPTERLTIMQFMNHPWINQSMEVPQT 315
>KAPA_YEAST (P06244) cAMP-dependent protein kinase type 1 (EC 2.7.11.11) (PKA| 1) (CDC25-suppressing protein kinase) (PK-25) Length = 397 Score = 70.5 bits (171), Expect = 4e-12 Identities = 41/105 (39%), Positives = 59/105 (56%), Gaps = 5/105 (4%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GTP YIAPEV+S + Y+ K D WS G+ +Y ML G PF D N KT +IL+ + Sbjct: 244 GTPDYIAPEVVSTKPYN-KSIDWWSFGILIYEMLAGYTPFYD----SNTMKTYEKILNAE 298 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRI-----TIQEIKNHPWF 343 P + + + + LLSR+ + QR+ +++KNHPWF Sbjct: 299 LRFPPF--FNEDVKDLLSRLITRDLSQRLGNLQNGTEDVKNHPWF 341
>PLO1_SCHPO (P50528) Serine/threonine-protein kinase plo1 (EC 2.7.11.21)| Length = 683 Score = 70.5 bits (171), Expect = 4e-12 Identities = 39/101 (38%), Positives = 58/101 (57%), Gaps = 1/101 (0%) Frame = +2 Query: 44 GTPAYIAPEVL-SRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSV 220 GTP YIAPE+L + +E D+WS GV +Y +L+G PF+D + +RK I + Sbjct: 200 GTPNYIAPEILFNSKEGHSFEVDLWSAGVVMYALLIGKPPFQDKEVKTIYRK----IKAN 255 Query: 221 QYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWF 343 YS P V IS E + L+S + +P R +I +I +H +F Sbjct: 256 SYSFPSNVDISAEAKDLISSLLTHDPSIRPSIDDIVDHEFF 296
>KCC1B_RAT (O70150) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase homolog) Length = 343 Score = 70.1 bits (170), Expect = 5e-12 Identities = 34/99 (34%), Positives = 55/99 (55%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GTP Y+APE+L ++ Y GK DVW+ GV Y++L G PF D +P+ F + + S + Sbjct: 174 GTPGYVAPELLEQKPY-GKAVDVWALGVISYILLCGYPPFYDESDPELFSQILR--ASYE 230 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 + P + IS + + + +P++R T Q+ H W Sbjct: 231 FDSPFWDDISESAKDFIRHLLERDPQKRFTCQQALQHLW 269
>KCC1B_MOUSE (Q9QYK9) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase homolog) Length = 343 Score = 70.1 bits (170), Expect = 5e-12 Identities = 34/99 (34%), Positives = 55/99 (55%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GTP Y+APE+L ++ Y GK DVW+ GV Y++L G PF D +P+ F + + S + Sbjct: 174 GTPGYVAPELLEQKPY-GKAVDVWALGVISYILLCGYPPFYDESDPELFSQILR--ASYE 230 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 + P + IS + + + +P++R T Q+ H W Sbjct: 231 FDSPFWDDISESAKDFIRHLLERDPQKRFTCQQALQHLW 269
>KCC1B_HUMAN (Q6P2M8) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase) Length = 343 Score = 70.1 bits (170), Expect = 5e-12 Identities = 34/99 (34%), Positives = 55/99 (55%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GTP Y+APE+L ++ Y GK DVW+ GV Y++L G PF D +P+ F + + S + Sbjct: 174 GTPGYVAPELLEQKPY-GKAVDVWALGVISYILLCGYPPFYDESDPELFSQILR--ASYE 230 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 + P + IS + + + +P++R T Q+ H W Sbjct: 231 FDSPFWDDISESAKDFIRHLLERDPQKRFTCQQALRHLW 269
>TSSK1_HUMAN (Q9BXA7) Testis-specific serine/threonine-protein kinase 1 (EC| 2.7.11.1) (TSSK-1) (Testis-specific kinase 1) (TSK-1) (Serine/threonine-protein kinase 22A) Length = 367 Score = 70.1 bits (170), Expect = 5e-12 Identities = 36/103 (34%), Positives = 57/103 (55%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 K+ G+PAY APEVL Y KV D+WS GV LY+M+ G+ P++D N +K + Sbjct: 173 KTFCGSPAYAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDD----SNIKKMLRIQ 228 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 + + P ++ EC+ L+ + + +R+ I EI +H W Sbjct: 229 KEHRVNFPRSKHLTGECKDLIYHMLQPDVNRRLHIDEILSHCW 271
>KCC1A_RAT (Q63450) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 374 Score = 70.1 bits (170), Expect = 5e-12 Identities = 34/99 (34%), Positives = 54/99 (54%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GTP Y+APEVL+++ Y K D WS GV Y++L G PF D ++ K F + + + Sbjct: 180 GTPGYVAPEVLAQKPYS-KAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILK--AEYE 236 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 + P + IS + + + +PE+R T ++ HPW Sbjct: 237 FDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPW 275
>KCC1A_MOUSE (Q91YS8) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 374 Score = 70.1 bits (170), Expect = 5e-12 Identities = 34/99 (34%), Positives = 54/99 (54%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GTP Y+APEVL+++ Y K D WS GV Y++L G PF D ++ K F + + + Sbjct: 180 GTPGYVAPEVLAQKPYS-KAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILK--AEYE 236 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 + P + IS + + + +PE+R T ++ HPW Sbjct: 237 FDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPW 275
>KCC1A_HUMAN (Q14012) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 370 Score = 70.1 bits (170), Expect = 5e-12 Identities = 34/99 (34%), Positives = 54/99 (54%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GTP Y+APEVL+++ Y K D WS GV Y++L G PF D ++ K F + + + Sbjct: 180 GTPGYVAPEVLAQKPYS-KAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILK--AEYE 236 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 + P + IS + + + +PE+R T ++ HPW Sbjct: 237 FDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPW 275
>MAPK3_HUMAN (Q16644) MAP kinase-activated protein kinase 3 (EC 2.7.11.1)| (MAPK-activated protein kinase 3) (MAPKAP kinase 3) (MAPKAPK-3) (Chromosome 3p kinase) (3pK) Length = 382 Score = 69.7 bits (169), Expect = 7e-12 Identities = 37/110 (33%), Positives = 58/110 (52%), Gaps = 2/110 (1%) Frame = +2 Query: 47 TPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQY 226 TP Y+APEVL +YD K D+WS GV +Y++L G PF RI QY Sbjct: 205 TPYYVAPEVLGPEKYD-KSCDMWSLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRLGQY 263 Query: 227 SVP--DYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPIEMT 370 P ++ +S + + L+ + +P +R+TI + NHPW +++ + T Sbjct: 264 GFPNPEWSEVSEDAKQLIRLLLKTDPTERLTITQFMNHPWINQSMVVPQT 313
>MAPK3_BOVIN (Q3SYZ2) MAP kinase-activated protein kinase 3 (EC 2.7.11.1)| (MAPK-activated protein kinase 3) (MAPKAP kinase 3) (MAPKAPK-3) Length = 384 Score = 69.7 bits (169), Expect = 7e-12 Identities = 37/110 (33%), Positives = 58/110 (52%), Gaps = 2/110 (1%) Frame = +2 Query: 47 TPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQY 226 TP Y+APEVL +YD K D+WS GV +Y++L G PF RI QY Sbjct: 207 TPYYVAPEVLGPEKYD-KSCDMWSLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRLGQY 265 Query: 227 SVP--DYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPIEMT 370 P ++ +S + + L+ + +P +R+TI + NHPW +++ + T Sbjct: 266 GFPSPEWSEVSEDAKQLIRLLLKTDPTERLTITQFMNHPWINQSMVVPQT 315
>KPCT_MOUSE (Q02111) Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)| Length = 707 Score = 69.3 bits (168), Expect = 9e-12 Identities = 41/102 (40%), Positives = 60/102 (58%), Gaps = 2/102 (1%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GTP YIAPE+L ++Y+ V D WS GV +Y ML+G PF DE + F S++ Sbjct: 541 GTPDYIAPEILLGQKYNHSV-DWWSFGVLVYEMLIGQSPFHGQDEEELFH-------SIR 592 Query: 224 YSVPDYVR-ISMECRHLLSRIFVANPEQRITIQ-EIKNHPWF 343 P Y R + E + LL ++FV PE+R+ ++ +I+ HP F Sbjct: 593 MDNPFYPRWLEREAKDLLVKLFVREPEKRLGVRGDIRQHPLF 634
>CHK1_RAT (Q91ZN7) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 69.3 bits (168), Expect = 9e-12 Identities = 38/104 (36%), Positives = 56/104 (53%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GT Y+APE+L R+E+ + DVWSCG+ L ML G P+ D+P + + + + Sbjct: 169 GTLPYVAPELLKRKEFHAEPVDVWSCGIVLTAMLAGELPW---DQPSDSCQEYSDWKEKK 225 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNL 355 + + +I LL +I V NP RITI +IK W+ K L Sbjct: 226 TYLNPWKKIDSAPLALLHKILVENPSARITIPDIKKDRWYNKPL 269
>TRIB3_RAT (Q9WTQ6) Tribbles homolog 3 (TRB-3) (Neuronal cell death-inducible| putative kinase) Length = 349 Score = 69.3 bits (168), Expect = 9e-12 Identities = 38/98 (38%), Positives = 53/98 (54%), Gaps = 1/98 (1%) Frame = +2 Query: 50 PAYIAPEVLSRR-EYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQY 226 PAY+ PE+LS R Y G+ ADVWS GV L+ ML G YPF+D + F K I + Sbjct: 218 PAYVGPEILSSRPSYSGRAADVWSLGVALFTMLAGRYPFQDSEPALLFGK----IRRGTF 273 Query: 227 SVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 ++P+ + S C L+ + P +R+ I HPW Sbjct: 274 ALPEGLSASARC--LIRCLLRREPSERLVALGILLHPW 309
>PLK4_MOUSE (Q64702) Serine/threonine-protein kinase PLK4 (EC 2.7.11.21)| (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine-protein kinase 18) Length = 925 Score = 69.3 bits (168), Expect = 9e-12 Identities = 35/111 (31%), Positives = 63/111 (56%) Frame = +2 Query: 20 HSQPKSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKT 199 H + + GTP YI+PE+ +R + G +D+WS G Y +L+G PF D D KN T Sbjct: 165 HEKHYTLCGTPNYISPEIATRSAH-GLESDIWSLGCMFYTLLIGRPPF-DTDTVKN---T 219 Query: 200 ITRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKN 352 + +++ Y +P + +S E + L+ ++ NP R+++ + +HP+ +N Sbjct: 220 LNKVVLADYEMPAF--LSREAQDLIHQLLRRNPADRLSLSSVLDHPFMSRN 268
>KK31_SCHPO (Q9HFF4) Probable serine/threonine-protein kinase C110.01 (EC| 2.7.11.1) Length = 1023 Score = 69.3 bits (168), Expect = 9e-12 Identities = 38/114 (33%), Positives = 63/114 (55%), Gaps = 5/114 (4%) Frame = +2 Query: 35 STVGTPAYIAPEVLSRRE--YDGKVADVWSCGVTLYVMLVGAYPF-EDPDEP--KNFRKT 199 ++ G+P Y APE+++ + Y G AD+WSCGV LY ML G PF +DP P +N + Sbjct: 669 TSCGSPCYAAPELVNCKSGMYAGTQADIWSCGVILYAMLAGYLPFDDDPHNPNGENVPRL 728 Query: 200 ITRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPI 361 I S P++ + + R +L +I V +P +R+ + I NH + ++ + Sbjct: 729 YRYICSTPLIFPEFFK--SKARDILKKILVPDPAKRVRMSAIMNHAYLRSHVSL 780
>CDPK1_ORYSA (P53682) Calcium-dependent protein kinase, isoform 1 (EC 2.7.11.1)| (CDPK 1) Length = 534 Score = 68.9 bits (167), Expect = 1e-11 Identities = 36/107 (33%), Positives = 55/107 (51%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 + VG+P YIAPEVL +R G AD+W+ GV LYV+L G PF + + K + Sbjct: 232 REVVGSPYYIAPEVLEKRY--GPEADIWTAGVILYVLLTGVPPFWADTQSGIYEKVLDG- 288 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKN 352 + + + RIS + L+ ++ P +R+ E+ HPW N Sbjct: 289 -RIDFKSNRWPRISDSAKDLIKKMLCPYPSERLKAHEVLKHPWICDN 334
>KS6A2_MOUSE (Q9WUT3) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (Protein-tyrosine kinase Mpk-9) (MAP kinase-activated protein kinase 1c) (M Length = 733 Score = 68.9 bits (167), Expect = 1e-11 Identities = 39/121 (32%), Positives = 67/121 (55%), Gaps = 3/121 (2%) Frame = +2 Query: 47 TPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFED-PDEPKNFRKTITRILSVQ 223 T ++APEVL R+ YD DVWS G+ LY ML G PF + PD+ + + RI S + Sbjct: 574 TANFVAPEVLKRQGYDA-ACDVWSLGILLYTMLAGFTPFANGPDDTPE--EILARIGSGK 630 Query: 224 YSVP--DYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPIEMTDEYQMSLHM 397 Y++ ++ IS + ++S++ +P+QR+T ++ HPW + + + +H+ Sbjct: 631 YALSGGNWDSISDAAKDVVSKMLHVDPQQRLTAVQVLKHPWIVNREYLSQNQLSRQDVHL 690 Query: 398 V 400 V Sbjct: 691 V 691 Score = 65.9 bits (159), Expect = 1e-10 Identities = 40/109 (36%), Positives = 63/109 (57%), Gaps = 5/109 (4%) Frame = +2 Query: 35 STVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRIL 214 S GT Y+APEV++RR + + AD WS GV ++ ML G+ PF+ D ++T+ IL Sbjct: 218 SFCGTIEYMAPEVVNRRGHT-QSADWWSFGVLMFEMLTGSLPFQGKDR----KETMALIL 272 Query: 215 SVQYSVPDYVRISMECRHLLSRIFVANPEQRI-----TIQEIKNHPWFL 346 + +P + +S E + LL +F NP R+ ++EIK HP+F+ Sbjct: 273 KAKLGMPQF--LSAEAQSLLRALFKRNPCNRLGAGVDGVEEIKRHPFFV 319
>KS6A3_MOUSE (P18654) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B) Length = 740 Score = 68.6 bits (166), Expect = 1e-11 Identities = 47/137 (34%), Positives = 73/137 (53%), Gaps = 6/137 (4%) Frame = +2 Query: 2 SKSSVLHSQPK-STVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDE 178 SK S+ H + S GT Y+APEV++RR + + AD WS GV ++ ML G PF+ D Sbjct: 215 SKESIDHEKKAYSFCGTVEYMAPEVVNRRGHT-QSADWWSFGVLMFEMLTGTLPFQGKDR 273 Query: 179 PKNFRKTITRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRI-----TIQEIKNHPWF 343 ++T+T IL + +P + +S E + LL +F NP R+ ++EIK H +F Sbjct: 274 ----KETMTMILKAKLGMPQF--LSPEAQSLLRMLFKRNPANRLGAGPDGVEEIKRHSFF 327 Query: 344 LKNLPIEMTDEYQMSLH 394 I+ Y+ +H Sbjct: 328 ---STIDWNKLYRREIH 341 Score = 63.5 bits (153), Expect = 5e-10 Identities = 37/103 (35%), Positives = 58/103 (56%), Gaps = 3/103 (2%) Frame = +2 Query: 47 TPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFED-PDEPKNFRKTITRILSVQ 223 T ++APEVL R+ YD D+WS GV LY ML G PF + PD+ + + RI S + Sbjct: 581 TANFVAPEVLKRQGYDA-ACDIWSLGVLLYTMLTGYTPFANGPDDTP--EEILARIGSGK 637 Query: 224 YSVPD--YVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFL 346 +S+ + +S + L+S++ +P QR+T + HPW + Sbjct: 638 FSLSGGYWNSVSDTAKDLVSKMLHVDPHQRLTAALVLRHPWIV 680
>KS6A3_HUMAN (P51812) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protei Length = 740 Score = 68.6 bits (166), Expect = 1e-11 Identities = 47/137 (34%), Positives = 73/137 (53%), Gaps = 6/137 (4%) Frame = +2 Query: 2 SKSSVLHSQPK-STVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDE 178 SK S+ H + S GT Y+APEV++RR + + AD WS GV ++ ML G PF+ D Sbjct: 215 SKESIDHEKKAYSFCGTVEYMAPEVVNRRGHT-QSADWWSFGVLMFEMLTGTLPFQGKDR 273 Query: 179 PKNFRKTITRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRI-----TIQEIKNHPWF 343 ++T+T IL + +P + +S E + LL +F NP R+ ++EIK H +F Sbjct: 274 ----KETMTMILKAKLGMPQF--LSPEAQSLLRMLFKRNPANRLGAGPDGVEEIKRHSFF 327 Query: 344 LKNLPIEMTDEYQMSLH 394 I+ Y+ +H Sbjct: 328 ---STIDWNKLYRREIH 341 Score = 63.5 bits (153), Expect = 5e-10 Identities = 37/103 (35%), Positives = 58/103 (56%), Gaps = 3/103 (2%) Frame = +2 Query: 47 TPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFED-PDEPKNFRKTITRILSVQ 223 T ++APEVL R+ YD D+WS GV LY ML G PF + PD+ + + RI S + Sbjct: 581 TANFVAPEVLKRQGYDA-ACDIWSLGVLLYTMLTGYTPFANGPDDTP--EEILARIGSGK 637 Query: 224 YSVPD--YVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFL 346 +S+ + +S + L+S++ +P QR+T + HPW + Sbjct: 638 FSLSGGYWNSVSDTAKDLVSKMLHVDPHQRLTAALVLRHPWIV 680
>CDR1_SCHPO (P07334) Mitosis inducer protein kinase cdr1 (EC 2.7.11.1) (Protein| kinase nim1) Length = 593 Score = 68.2 bits (165), Expect = 2e-11 Identities = 39/101 (38%), Positives = 54/101 (53%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 G+ Y+APE++S + Y G ADVWSCGV LY +L PF +N +I Sbjct: 165 GSLHYLAPEIVSHKPYRGAPADVWSCGVILYSLLSNKLPFGG----QNTDVIYNKIRHGA 220 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFL 346 Y +P IS + LL R+ NP RITI E+ +HP+ + Sbjct: 221 YDLPS--SISSAAQDLLHRMLDVNPSTRITIPEVFSHPFLM 259
>KCC1D_MOUSE (Q8BW96) Calcium/calmodulin-dependent protein kinase type 1D (EC| 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) (mCKLiK) Length = 385 Score = 68.2 bits (165), Expect = 2e-11 Identities = 33/99 (33%), Positives = 53/99 (53%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GTP Y+APEVL+++ Y K D WS GV Y++L G PF D ++ K F + + + Sbjct: 183 GTPGYVAPEVLAQKPYS-KAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILK--AEYE 239 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 + P + IS + + + +P +R T ++ HPW Sbjct: 240 FDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPW 278
>KCC1D_HUMAN (Q8IU85) Calcium/calmodulin-dependent protein kinase type 1D (EC| 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) Length = 385 Score = 68.2 bits (165), Expect = 2e-11 Identities = 33/99 (33%), Positives = 53/99 (53%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GTP Y+APEVL+++ Y K D WS GV Y++L G PF D ++ K F + + + Sbjct: 183 GTPGYVAPEVLAQKPYS-KAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILK--AEYE 239 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 + P + IS + + + +P +R T ++ HPW Sbjct: 240 FDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPW 278
>TSSK2_MOUSE (O54863) Testis-specific serine/threonine-protein kinase 2 (EC| 2.7.11.1) (TSSK-2) (Testis-specific kinase 2) (TSK-2) (Serine/threonine-protein kinase 22B) Length = 357 Score = 67.8 bits (164), Expect = 3e-11 Identities = 39/113 (34%), Positives = 58/113 (51%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 K+ G+ AY APEV Y KV D+WS GV LY+M+ G+ P++D D K + R+ Sbjct: 173 KTFCGSAAYAAPEVRQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIKKLRIQKEHRV 232 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPIEMT 370 P ++ EC+ L+ RI + +R+ I EI +H W P M+ Sbjct: 233 -----DFPRSKNLTGECKDLIYRILQPDVNRRLHIDEILSHSWLQPPKPKAMS 280
>ST17A_RABIT (Q9GM70) Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP| kinase-related apoptosis-inducing protein kinase 1) (rDRAK1) Length = 397 Score = 67.8 bits (164), Expect = 3e-11 Identities = 38/109 (34%), Positives = 55/109 (50%), Gaps = 2/109 (1%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYD--GKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIT 205 + +GTP Y+APE+LS YD D+WS GV YVML G PF ++ + F Sbjct: 204 REIMGTPEYVAPEILS---YDPISMATDMWSIGVLTYVMLTGISPFLGDNKQETFLNISQ 260 Query: 206 RILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKN 352 LS YS ++ +S + ++ V PE R T +E HPW ++ Sbjct: 261 MNLS--YSEEEFDTVSESAVDFIKKLLVKKPEDRATAEECLKHPWLTQS 307
>TSSK1_MOUSE (Q61241) Testis-specific serine/threonine-protein kinase 1 (EC| 2.7.11.1) (TSSK-1) (Testis-specific kinase 1) (TSK-1) (Serine/threonine-protein kinase 22A) Length = 364 Score = 67.8 bits (164), Expect = 3e-11 Identities = 37/103 (35%), Positives = 57/103 (55%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 K+ G+ AY APEVL Y KV D+WS GV LY+M+ G+ P++D + K + R+ Sbjct: 173 KTFCGSAAYAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKLRIQKEHRV 232 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 + P ++ EC+ L+ R+ + +R+ I EI NH W Sbjct: 233 -----NFPRSKHLTGECKDLIYRMLQPDVNRRLHIDEILNHCW 270
>CDPK1_ARATH (Q06850) Calcium-dependent protein kinase, isoform AK1 (EC| 2.7.11.1) (CDPK) Length = 610 Score = 67.8 bits (164), Expect = 3e-11 Identities = 36/100 (36%), Positives = 57/100 (57%) Frame = +2 Query: 41 VGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSV 220 VG+P Y+APEVL +R G ADVWS GV +Y++L G PF E F + + + Sbjct: 312 VGSPYYVAPEVLRKRY--GPEADVWSAGVIVYILLSGVPPFWAETEQGIFEQVLHG--DL 367 Query: 221 QYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 +S + IS + L+ ++ V +P++R+T ++ HPW Sbjct: 368 DFSSDPWPSISESAKDLVRKMLVRDPKKRLTAHQVLCHPW 407
>TRIB3_MOUSE (Q8K4K2) Tribbles homolog 3 (TRB-3) (Neuronal cell death-inducible| putative kinase) Length = 354 Score = 67.8 bits (164), Expect = 3e-11 Identities = 39/98 (39%), Positives = 52/98 (53%), Gaps = 1/98 (1%) Frame = +2 Query: 50 PAYIAPEVLSRR-EYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQY 226 PAY+ PE+LS R Y GK ADVWS GV L+ ML G YPF D + F K I + Sbjct: 223 PAYVGPEILSSRPSYSGKAADVWSLGVALFTMLAGRYPFHDSEPVLLFGK----IRRGTF 278 Query: 227 SVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 ++P+ +S R L+ + P +R+ I HPW Sbjct: 279 ALPE--GLSAPARCLIRCLLRKEPSERLVALGILLHPW 314
>ST17A_HUMAN (Q9UEE5) Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP| kinase-related apoptosis-inducing protein kinase 1) Length = 414 Score = 67.4 bits (163), Expect = 3e-11 Identities = 42/137 (30%), Positives = 64/137 (46%), Gaps = 2/137 (1%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYD--GKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIT 205 + +GTP Y+APE+LS YD D+WS GV YVML G PF D+ + F Sbjct: 221 REIMGTPEYVAPEILS---YDPISMATDMWSIGVLTYVMLTGISPFLGNDKQETFLNISQ 277 Query: 206 RILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPIEMTDEYQM 385 +++ YS ++ +S + + V PE R T +E HPW ++ E + + Sbjct: 278 --MNLSYSEEEFDVLSESAVDFIRTLLVKKPEDRATAEECLKHPWLTQSSIQEPSFRMEK 335 Query: 386 SLHMVGVNAPPQSLEEI 436 +L S+ EI Sbjct: 336 ALEEANALQEGHSVPEI 352
>CDPK2_PLAF7 (Q8ICR0) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (PfCDPK2)| Length = 508 Score = 67.4 bits (163), Expect = 3e-11 Identities = 36/99 (36%), Positives = 57/99 (57%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GTP Y+AP+VL + YD K D+WS GV +Y +L G PF + + +K + Sbjct: 230 GTPYYVAPQVLDGK-YDKK-CDIWSSGVIMYTLLCGYPPFYGDTDNEVLKKV--KKGEFC 285 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 + D+ IS + ++L++++ NP +R TI+E NHPW Sbjct: 286 FYENDWGSISSDAKNLITKLLTYNPNERCTIEEALNHPW 324
>PK2_DICDI (P28178) Protein kinase 2 (EC 2.7.11.1)| Length = 479 Score = 67.4 bits (163), Expect = 3e-11 Identities = 43/120 (35%), Positives = 62/120 (51%), Gaps = 3/120 (2%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GTP Y+APEVL+ + G D WS G LY ML G PF +N +IL+ + Sbjct: 312 GTPEYLAPEVLNGHGH-GCAVDWWSLGTLLYEMLTGLPPFYS----QNVSTMYQKILNGE 366 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQ---EIKNHPWFLKNLPIEMTDEYQMSLH 394 +P Y IS E + LL + ++R+ + E+K HPWF KN+ E D ++ +H Sbjct: 367 LKIPTY--ISPEAKSLLEGLLTREVDKRLGTKGGGEVKQHPWF-KNIDWEKLDRKEVEVH 423
>PIM1_BOVIN (Q9N0P9) Proto-oncogene serine/threonine-protein kinase pim-1 (EC| 2.7.11.1) Length = 313 Score = 67.4 bits (163), Expect = 3e-11 Identities = 40/114 (35%), Positives = 53/114 (46%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GT Y PE + Y G+ A VWS G+ LY M+ G PFE +E V+ Sbjct: 203 GTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEE------------IVR 250 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPIEMTDEYQM 385 V R+S EC+HL+ P R T +EI+NHPW L + T E + Sbjct: 251 GQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHL 304
>KS6A2_HUMAN (Q15349) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (MAP kinase-activated protein kinase 1c) (MAPKAPK1C) Length = 733 Score = 67.4 bits (163), Expect = 3e-11 Identities = 38/121 (31%), Positives = 66/121 (54%), Gaps = 3/121 (2%) Frame = +2 Query: 47 TPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFED-PDEPKNFRKTITRILSVQ 223 T ++APEVL R+ YD D+WS G+ LY ML G PF + PD+ + + RI S + Sbjct: 574 TANFVAPEVLKRQGYDA-ACDIWSLGILLYTMLAGFTPFANGPDDTPE--EILARIGSGK 630 Query: 224 YSVP--DYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPIEMTDEYQMSLHM 397 Y++ ++ IS + ++S++ +P QR+T ++ HPW + + + +H+ Sbjct: 631 YALSGGNWDSISDAAKDVVSKMLHVDPHQRLTAMQVLKHPWVVNREYLSPNQLSRQDVHL 690 Query: 398 V 400 V Sbjct: 691 V 691 Score = 66.2 bits (160), Expect = 7e-11 Identities = 43/121 (35%), Positives = 69/121 (57%), Gaps = 6/121 (4%) Frame = +2 Query: 2 SKSSVLHSQPK-STVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDE 178 SK ++ H + S GT Y+APEV++RR + + AD WS GV ++ ML G+ PF+ D Sbjct: 206 SKEAIDHDKRAYSFCGTIEYMAPEVVNRRGHT-QSADWWSFGVLMFEMLTGSLPFQGKDR 264 Query: 179 PKNFRKTITRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRI-----TIQEIKNHPWF 343 ++T+ IL + +P + +S E + LL +F NP R+ ++EIK HP+F Sbjct: 265 ----KETMALILKAKLGMPQF--LSGEAQSLLRALFKRNPCNRLGAGIDGVEEIKRHPFF 318 Query: 344 L 346 + Sbjct: 319 V 319
>KS6A1_RAT (Q63531) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 67.4 bits (163), Expect = 3e-11 Identities = 39/122 (31%), Positives = 67/122 (54%), Gaps = 4/122 (3%) Frame = +2 Query: 47 TPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFED--PDEPKNFRKTITRILSV 220 T ++APEVL R+ YD + D+WS GV LY ML G PF + D P+ +TRI S Sbjct: 577 TANFVAPEVLKRQGYD-EGCDIWSLGVLLYTMLAGYTPFANGPSDTPEEI---LTRISSG 632 Query: 221 QYSVP--DYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPIEMTDEYQMSLH 394 ++++ ++ +S + L+S++ +P QR+T +++ HPW + + + L Sbjct: 633 KFTLSGGNWNTVSETAKDLVSKMLHVDPHQRLTAKQVLQHPWITQKDKLPQSQLSHQDLQ 692 Query: 395 MV 400 +V Sbjct: 693 LV 694 Score = 62.0 bits (149), Expect = 1e-09 Identities = 41/120 (34%), Positives = 66/120 (55%), Gaps = 6/120 (5%) Frame = +2 Query: 2 SKSSVLHSQPK-STVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDE 178 SK ++ H + S GT Y+APEV++R+ + AD WS GV ++ ML G+ PF+ D Sbjct: 209 SKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHTHS-ADWWSYGVLMFEMLTGSLPFQGKDR 267 Query: 179 PKNFRKTITRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRI-----TIQEIKNHPWF 343 ++T+T IL + +P + +S E + LL +F NP R+ +EIK H ++ Sbjct: 268 ----KETMTLILKAKLGMPQF--LSTEAQSLLRALFKRNPANRLGSGPDGAEEIKRHIFY 321
>CDPK2_PLAFK (O15865) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (PfCDPK2)| Length = 512 Score = 67.4 bits (163), Expect = 3e-11 Identities = 36/99 (36%), Positives = 57/99 (57%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GTP Y+AP+VL + YD K D+WS GV +Y +L G PF + + +K + Sbjct: 230 GTPYYVAPQVLDGK-YDKK-CDIWSSGVIMYTLLCGYPPFYGDTDNEVLKKV--KKGEFC 285 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 + D+ IS + ++L++++ NP +R TI+E NHPW Sbjct: 286 FYENDWGSISSDAKNLITKLLTYNPNERCTIEEALNHPW 324
>CDPK_DAUCA (P28582) Calcium-dependent protein kinase (EC 2.7.11.1) (CDPK)| Length = 532 Score = 67.4 bits (163), Expect = 3e-11 Identities = 46/157 (29%), Positives = 75/157 (47%), Gaps = 5/157 (3%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 ++ VG+ Y+APEVL RR Y GK D+WS GV LY++L G PF +E F + + Sbjct: 240 RNIVGSAYYVAPEVL-RRSY-GKEIDIWSAGVILYILLSGVPPFWAENEKGIFDAILEGV 297 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWF-----LKNLPIEMTDE 376 + + + +S + L+ ++ +P +RIT ++ +HPW + PI+ Sbjct: 298 --IDFESEPWPSVSNSAKDLVRKMLTQDPRRRITSAQVLDHPWMREGGEASDKPIDSAVL 355 Query: 377 YQMSLHMVGVNAPPQSLEEIMAIIQEARIPGDGSKFA 487 +M +L+ I + E I G S FA Sbjct: 356 SRMKQFRAMNKLKQLALKVIAESLSEEEIKGLKSMFA 392
>PIM1_HUMAN (P11309) Proto-oncogene serine/threonine-protein kinase Pim-1 (EC| 2.7.11.1) Length = 404 Score = 67.0 bits (162), Expect = 4e-11 Identities = 39/114 (34%), Positives = 53/114 (46%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GT Y PE + Y G+ A VWS G+ LY M+ G PFE +E ++ Sbjct: 294 GTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEE------------IIR 341 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPIEMTDEYQM 385 V R+S EC+HL+ P R T +EI+NHPW L + T E + Sbjct: 342 GQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHL 395
>ST38L_MOUSE (Q7TSE6) Serine/threonine-protein kinase 38-like (EC 2.7.11.1)| (NDR2 protein kinase) (Nuclear Dbf2-related kinase 2) Length = 464 Score = 67.0 bits (162), Expect = 4e-11 Identities = 42/106 (39%), Positives = 62/106 (58%), Gaps = 3/106 (2%) Frame = +2 Query: 35 STVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRIL 214 STVGTP YIAPEV + Y+ K+ D WS GV +Y ML+G PF + +RK ++ Sbjct: 282 STVGTPDYIAPEVFMQTGYN-KLCDWWSLGVIMYEMLIGFPPFCSETPQETYRKVMSWKE 340 Query: 215 SVQYSVPDYVRISMECRHLLSRIFVANPEQRI---TIQEIKNHPWF 343 ++ + P V +S + + L+ R F + E RI ++EIK HP+F Sbjct: 341 TLAF--PPEVPVSEKAKDLILR-FCTDSENRIGNGGVEEIKGHPFF 383
>CHK1_MOUSE (O35280) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 67.0 bits (162), Expect = 4e-11 Identities = 37/104 (35%), Positives = 55/104 (52%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GT Y+APE+L R+E+ + DVWSCG+ L ML G P+ D+P + + + + Sbjct: 169 GTLPYVAPELLKRKEFHAEPVDVWSCGIVLTAMLAGELPW---DQPSDSCQEYSDWKEKK 225 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNL 355 + + +I LL +I V P RITI +IK W+ K L Sbjct: 226 TYLNPWKKIDSAPLALLHKILVETPSARITIPDIKKDRWYNKPL 269
>POLO_DROME (P52304) Serine/threonine-protein kinase polo (EC 2.7.11.21)| Length = 576 Score = 67.0 bits (162), Expect = 4e-11 Identities = 40/112 (35%), Positives = 61/112 (54%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 K+ GTP YIAPE+L+++ + +V D+WS G +Y +LVG PF E K + T ++I Sbjct: 181 KTLCGTPNYIAPEILTKKGHSFEV-DIWSIGCVMYTLLVGQPPF----ETKTLKDTYSKI 235 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPIEM 367 +Y VP Y+R ++ + NPE R I ++ N FLK + M Sbjct: 236 KKCEYRVPSYLR--KPAADMVIAMLQPNPESRPAIGQLLNFE-FLKGSKVPM 284
>KS6AA_CHICK (P18652) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 752 Score = 66.6 bits (161), Expect = 6e-11 Identities = 39/102 (38%), Positives = 61/102 (59%), Gaps = 4/102 (3%) Frame = +2 Query: 47 TPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFED--PDEPKNFRKTITRILSV 220 T ++APEVL R+ YD + D+WS GV LY ML G PF + D P+ + +TRI Sbjct: 594 TANFVAPEVLKRQGYD-EGCDIWSLGVLLYTMLAGCTPFANGPSDTPE---EILTRIGGG 649 Query: 221 QYSV--PDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 ++SV ++ IS + L+S++ +P QR+T +++ HPW Sbjct: 650 KFSVNGGNWDTISDVAKDLVSKMLHVDPHQRLTAKQVLQHPW 691 Score = 66.2 bits (160), Expect = 7e-11 Identities = 42/120 (35%), Positives = 67/120 (55%), Gaps = 6/120 (5%) Frame = +2 Query: 2 SKSSVLHSQPK-STVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDE 178 SK ++ H + S GT Y+APEV++R+ + AD WS GV ++ ML G+ PF+ D Sbjct: 227 SKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHS-ADWWSYGVLMFEMLTGSLPFQGKDR 285 Query: 179 PKNFRKTITRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRI-----TIQEIKNHPWF 343 ++T+T IL + +P + +S E + LL +F NP R+ +EIK HP++ Sbjct: 286 ----KETMTLILKAKLGMPQF--LSAEAQSLLRALFKRNPANRLGSGPDGAEEIKRHPFY 339
>PLK2_HUMAN (Q9NYY3) Serine/threonine-protein kinase PLK2 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-2) (Serine/threonine-protein kinase SNK) (Serum-inducible kinase) Length = 685 Score = 66.6 bits (161), Expect = 6e-11 Identities = 35/111 (31%), Positives = 64/111 (57%) Frame = +2 Query: 17 LHSQPKSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRK 196 L + ++ GTP Y++PEVL+++ + G +D+W+ G +Y ML+G PF E N ++ Sbjct: 233 LEHRRRTICGTPNYLSPEVLNKQGH-GCESDIWALGCVMYTMLLGRPPF----ETTNLKE 287 Query: 197 TITRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLK 349 T I +Y++P + +HL++ + NPE R ++ +I H +FL+ Sbjct: 288 TYRCIREARYTMPS--SLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFFLQ 336
>KPCD_HUMAN (Q05655) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 676 Score = 66.6 bits (161), Expect = 6e-11 Identities = 42/109 (38%), Positives = 59/109 (54%), Gaps = 2/109 (1%) Frame = +2 Query: 23 SQPKSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTI 202 S+ + GTP YIAPE+L +Y V D WS GV LY ML+G PF DE + F Sbjct: 503 SRASTFCGTPDYIAPEILQGLKYTFSV-DWWSFGVLLYEMLIGQSPFHGDDEDELFE--- 558 Query: 203 TRILSVQYSVPDYVR-ISMECRHLLSRIFVANPEQRITIQ-EIKNHPWF 343 S++ P Y R I+ E + +L ++F P +R+ + IK HP+F Sbjct: 559 ----SIRVDTPHYPRWITKESKDILEKLFEREPTKRLGMTGNIKIHPFF 603
>PLK1_RAT (Q62673) Serine/threonine-protein kinase PLK1 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-1) Length = 603 Score = 66.6 bits (161), Expect = 6e-11 Identities = 40/104 (38%), Positives = 59/104 (56%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 K+ GTP YIAPEVLS++ + +V DVWS G +Y +LVG PF E ++T RI Sbjct: 209 KTLCGTPNYIAPEVLSKKGHSFEV-DVWSIGCIMYTLLVGKPPF----ETSCLKETYLRI 263 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWF 343 +YS+P + I+ L+ ++ +P R TI E+ N +F Sbjct: 264 KKNEYSIPKH--INPVAASLIQKMLQTDPAARPTIHELLNDEFF 305
>PLK1_MOUSE (Q07832) Serine/threonine-protein kinase PLK1 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13) Length = 603 Score = 66.6 bits (161), Expect = 6e-11 Identities = 40/104 (38%), Positives = 59/104 (56%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 K+ GTP YIAPEVLS++ + +V DVWS G +Y +LVG PF E ++T RI Sbjct: 209 KTLCGTPNYIAPEVLSKKGHSFEV-DVWSIGCIMYTLLVGKPPF----ETSCLKETYLRI 263 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWF 343 +YS+P + I+ L+ ++ +P R TI E+ N +F Sbjct: 264 KKNEYSIPKH--INPVAASLIQKMLQTDPTARPTIHELLNDEFF 305
>PLK1_HUMAN (P53350) Serine/threonine-protein kinase PLK1 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13) Length = 603 Score = 66.6 bits (161), Expect = 6e-11 Identities = 40/104 (38%), Positives = 59/104 (56%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 K+ GTP YIAPEVLS++ + +V DVWS G +Y +LVG PF E ++T RI Sbjct: 209 KTLCGTPNYIAPEVLSKKGHSFEV-DVWSIGCIMYTLLVGKPPF----ETSCLKETYLRI 263 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWF 343 +YS+P + I+ L+ ++ +P R TI E+ N +F Sbjct: 264 KKNEYSIPKH--INPVAASLIQKMLQTDPTARPTINELLNDEFF 305
>PLK2_RAT (Q9R012) Serine/threonine-protein kinase PLK2 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-2) (Serine/threonine-protein kinase SNK) (Serum-inducible kinase) Length = 682 Score = 66.6 bits (161), Expect = 6e-11 Identities = 35/111 (31%), Positives = 64/111 (57%) Frame = +2 Query: 17 LHSQPKSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRK 196 L + ++ GTP Y++PEVL+++ + G +D+W+ G +Y ML+G PF E N ++ Sbjct: 230 LEHRRRTICGTPNYLSPEVLNKQGH-GCESDIWALGCVMYTMLLGRPPF----ETTNLKE 284 Query: 197 TITRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLK 349 T I +Y++P + +HL++ + NPE R ++ +I H +FL+ Sbjct: 285 TYRCIREARYTMPS--SLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFFLQ 333
>PLK2_MOUSE (P53351) Serine/threonine-protein kinase PLK2 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-2) (Serine/threonine-protein kinase SNK) (Serum-inducible kinase) Length = 682 Score = 66.6 bits (161), Expect = 6e-11 Identities = 35/111 (31%), Positives = 64/111 (57%) Frame = +2 Query: 17 LHSQPKSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRK 196 L + ++ GTP Y++PEVL+++ + G +D+W+ G +Y ML+G PF E N ++ Sbjct: 230 LEHRRRTICGTPNYLSPEVLNKQGH-GCESDIWALGCVMYTMLLGRPPF----ETTNLKE 284 Query: 197 TITRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLK 349 T I +Y++P + +HL++ + NPE R ++ +I H +FL+ Sbjct: 285 TYRCIREARYTMPS--SLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFFLQ 333
>KPCD_MOUSE (P28867) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 674 Score = 66.6 bits (161), Expect = 6e-11 Identities = 39/102 (38%), Positives = 58/102 (56%), Gaps = 2/102 (1%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GTP YIAPE+L +Y V D WS GV LY ML+G PF DE + F S++ Sbjct: 508 GTPDYIAPEILQGLKYSFSV-DWWSFGVLLYEMLIGQSPFHGDDEDELFE-------SIR 559 Query: 224 YSVPDYVR-ISMECRHLLSRIFVANPEQRITIQ-EIKNHPWF 343 P Y R I+ E + ++ ++F +P++R+ + I+ HP+F Sbjct: 560 VDTPHYPRWITKESKDIMEKLFERDPDKRLGVTGNIRIHPFF 601
>DAPK1_HUMAN (P53355) Death-associated protein kinase 1 (EC 2.7.11.1) (DAP| kinase 1) Length = 1432 Score = 66.6 bits (161), Expect = 6e-11 Identities = 35/105 (33%), Positives = 59/105 (56%), Gaps = 2/105 (1%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 K+ GTP ++APE+++ G AD+WS GV Y++L GA PF + ++T+ + Sbjct: 175 KNIFGTPEFVAPEIVNYEPL-GLEADMWSIGVITYILLSGASPFLGDTK----QETLANV 229 Query: 212 LSVQYSVPD--YVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 +V Y D + S + + R+ V +P++R+TIQ+ HPW Sbjct: 230 SAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPW 274
>AURKC_HUMAN (Q9UQB9) Serine/threonine-protein kinase 13 (EC 2.7.11.1)| (Aurora/Ipl1/Eg2 protein 2) (Aurora/Ipl1-related kinase 3) (Aurora-C) Length = 309 Score = 66.2 bits (160), Expect = 7e-11 Identities = 38/103 (36%), Positives = 55/103 (53%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 K+ GT Y+ PE++ R YD KV D+W GV Y +LVG PFE + +R RI Sbjct: 197 KTMCGTLDYLPPEMIEGRTYDEKV-DLWCIGVLCYELLVGYPPFESASHSETYR----RI 251 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 L V P + + + R L+SR+ P +R+ + +I HPW Sbjct: 252 LKVDVRFP--LSMPLGARDLISRLLRYQPLERLPLAQILKHPW 292
>NUAK1_MOUSE (Q641K5) NUAK family, SNF1-like kinase 1 (EC 2.7.11.1)| Length = 658 Score = 66.2 bits (160), Expect = 7e-11 Identities = 34/99 (34%), Positives = 54/99 (54%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 G+P Y +PE+++ R Y G D W+ GV LY ++ G PF+ D + I +I S + Sbjct: 215 GSPLYASPEIVNGRPYRGPEVDSWALGVLLYTLIYGTMPFDGFDH----KNLIRQISSGE 270 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 Y P + R L+ + + NP++R TI++I NH W Sbjct: 271 YREPTQ---PSDARGLIRWMLMVNPDRRATIEDIANHWW 306
>ST38L_HUMAN (Q9Y2H1) Serine/threonine-protein kinase 38-like (EC 2.7.11.1)| (NDR2 protein kinase) (Nuclear Dbf2-related kinase 2) Length = 464 Score = 66.2 bits (160), Expect = 7e-11 Identities = 43/106 (40%), Positives = 61/106 (57%), Gaps = 3/106 (2%) Frame = +2 Query: 35 STVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRIL 214 STVGTP YIAPEV + Y+ K+ D WS GV +Y ML+G PF + +RK + Sbjct: 282 STVGTPDYIAPEVFMQTGYN-KLCDWWSLGVIMYEMLIGYPPFCSETPQETYRKVMNWKE 340 Query: 215 SVQYSVPDYVRISMECRHLLSRIFVANPEQRI---TIQEIKNHPWF 343 ++ + P V IS + + L+ R F + E RI ++EIK HP+F Sbjct: 341 TLVF--PPEVPISEKAKDLILR-FCIDSENRIGNSGVEEIKGHPFF 383
>AURKB_RAT (O55099) Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-| and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora-B) Length = 343 Score = 66.2 bits (160), Expect = 7e-11 Identities = 32/107 (29%), Positives = 58/107 (54%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 K+ GT Y+ PE++ R ++ ++ D+W GV Y ++VG PFE P + +R+ + Sbjct: 234 KTMCGTLDYLPPEMIEGRMHN-EMVDLWCIGVLCYELMVGNPPFESPSHSETYRRIVKVD 292 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKN 352 L S+P + + L+S++ NP QR+ ++++ HPW N Sbjct: 293 LKFPSSMP------LGAKDLISKLLKHNPSQRLPLEQVSAHPWVRAN 333
>KCC1G_HUMAN (Q96NX5) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 476 Score = 66.2 bits (160), Expect = 7e-11 Identities = 34/99 (34%), Positives = 53/99 (53%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GTP Y+APEVL+++ Y K D WS GV Y++L G PF + E K F K + + Sbjct: 181 GTPGYVAPEVLAQKPYS-KAVDCWSIGVITYILLCGYPPFYEETESKLFEK--IKEGYYE 237 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 + P + IS + + + +P +R T ++ +HPW Sbjct: 238 FESPFWDDISESAKDFICHLLEKDPNERYTCEKALSHPW 276
>KS6A1_MOUSE (P18653) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 724 Score = 66.2 bits (160), Expect = 7e-11 Identities = 38/122 (31%), Positives = 67/122 (54%), Gaps = 4/122 (3%) Frame = +2 Query: 47 TPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFED--PDEPKNFRKTITRILSV 220 T ++APEVL R+ YD + D+WS G+ LY ML G PF + D P+ +TRI S Sbjct: 566 TANFVAPEVLKRQGYD-EGCDIWSLGILLYTMLAGYTPFANGPSDTPEEI---LTRIGSG 621 Query: 221 QYSVP--DYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPIEMTDEYQMSLH 394 ++++ ++ +S + L+S++ +P QR+T +++ HPW + + + L Sbjct: 622 KFTLSGGNWNTVSETAKDLVSKMLHVDPHQRLTAKQVLQHPWITQKDKLPQSQLSHQDLQ 681 Query: 395 MV 400 +V Sbjct: 682 LV 683 Score = 45.1 bits (105), Expect = 2e-04 Identities = 38/120 (31%), Positives = 61/120 (50%), Gaps = 6/120 (5%) Frame = +2 Query: 2 SKSSVLHSQPK-STVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDE 178 SK ++ H + S GT Y+APEV++R+ + AD WS GV L+G Sbjct: 209 SKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHTHS-ADWWSYGV-----LMG--------- 253 Query: 179 PKNFRKTITRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRI-----TIQEIKNHPWF 343 K+ ++T+T IL + +P + +S E + LL +F NP R+ +EIK H ++ Sbjct: 254 -KDRKETMTLILKAKLGMPQF--LSTEAQSLLRALFKRNPANRLGSGPDGAEEIKRHIFY 310
>DCAK2_MOUSE (Q6PGN3) Serine/threonine-protein kinase DCAMKL2 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 2) Length = 756 Score = 65.9 bits (159), Expect = 1e-10 Identities = 47/173 (27%), Positives = 84/173 (48%), Gaps = 10/173 (5%) Frame = +2 Query: 8 SSVLHSQPKSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKN 187 ++V+ + GTP Y+APE+++ Y KV DVW+ GV Y++L G PF + + Sbjct: 540 ATVVEGPLYTVCGTPTYVAPEIIAETGYGLKV-DVWAAGVITYILLCGFPPFRSENNLQ- 597 Query: 188 FRKTITRILS--VQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFL----- 346 +IL+ +++ P + I+ + L+S++ N E R T EI +HPW Sbjct: 598 -EDLFDQILAGKLEFPAPYWDNITDSAKELISQMLQVNVEARCTAGEILSHPWVSDDASQ 656 Query: 347 -KNLPIEMTDEYQMSLHMVGVNAPPQ--SLEEIMAIIQEARIPGDGSKFAGQL 496 N+ E+T + + + NA P+ S +++I + +G F +L Sbjct: 657 ENNMQAEVTGKLKQHFN----NALPKQNSTTTGVSVIMNTALDKEGQIFCSKL 705
>KSG1_SCHPO (Q12701) Serine/threonine-protein kinase ksg1 (EC 2.7.11.1)| Length = 592 Score = 65.9 bits (159), Expect = 1e-10 Identities = 38/104 (36%), Positives = 58/104 (55%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 +S VGT Y++PEVLS + G +D+W+ G L+ ML G PF +E F+ I Sbjct: 270 RSFVGTARYVSPEVLSDK-IAGTASDIWAFGCILFQMLAGKPPFVAGNEYLTFQS----I 324 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWF 343 L + Y +P IS L+ ++ V +P+ R+T+ EI HP+F Sbjct: 325 LHLSYEIPP--DISDVASDLIKKLLVLDPKDRLTVDEIHQHPFF 366
>KCC1G_RAT (Q7TNJ7) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 476 Score = 65.9 bits (159), Expect = 1e-10 Identities = 34/99 (34%), Positives = 52/99 (52%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GTP Y+APEVL+++ Y K D WS GV Y++L G PF + E K F K + + Sbjct: 181 GTPGYVAPEVLAQKPYS-KAVDCWSIGVITYILLCGYPPFYEETESKLFEK--IKEGYYE 237 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 + P + IS + + + +P +R T ++ HPW Sbjct: 238 FESPFWDDISESAKDFICHLLEKDPNERYTCEKALRHPW 276
>STK11_XENLA (Q91604) Serine/threonine-protein kinase 11 (EC 2.7.11.1)| (Serine/threonine-protein kinase XEEK1) (Egg and embryo kinase 1) Length = 432 Score = 65.9 bits (159), Expect = 1e-10 Identities = 40/114 (35%), Positives = 59/114 (51%), Gaps = 5/114 (4%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRRE-YDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITR 208 +++ G+PA+ PE+ + + + G D+WS GVTLY + G YPFE N K Sbjct: 214 RTSQGSPAFQPPEIANGLDTFSGFKVDIWSAGVTLYNITTGLYPFEG----DNIYKLFEN 269 Query: 209 ILSVQYSVPDYVRISMECRHLLSRIFVA----NPEQRITIQEIKNHPWFLKNLP 358 I YS+P+ EC LLS + +P +R +IQ+I+ H WF K P Sbjct: 270 IGKGDYSIPE------ECGPLLSDLLRGMLEYDPAKRFSIQQIRQHNWFRKKHP 317
>PIM1_RAT (P26794) Proto-oncogene serine/threonine-protein kinase Pim-1 (EC| 2.7.11.1) Length = 313 Score = 65.9 bits (159), Expect = 1e-10 Identities = 39/114 (34%), Positives = 53/114 (46%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GT Y PE + Y G+ A VWS G+ LY M+ G PFE +E V+ Sbjct: 203 GTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEE------------IVK 250 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPIEMTDEYQM 385 V R+S EC+HL+ P R + +EI+NHPW L + T E + Sbjct: 251 GQVYFRQRVSSECQHLIRWCLSLRPSDRPSFEEIQNHPWMQDVLLPQATAEIHL 304
>KCC1G_MOUSE (Q91VB2) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 477 Score = 65.9 bits (159), Expect = 1e-10 Identities = 34/99 (34%), Positives = 52/99 (52%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GTP Y+APEVL+++ Y K D WS GV Y++L G PF + E K F K + + Sbjct: 181 GTPGYVAPEVLAQKPYS-KAVDCWSIGVITYILLCGYPPFYEETESKLFEK--IKEGYYE 237 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 + P + IS + + + +P +R T ++ HPW Sbjct: 238 FESPFWDDISESAKDFICHLLEKDPNERYTCEKALRHPW 276
>KS6A_CAEEL (Q21734) Putative ribosomal protein S6 kinase alpha (EC 2.7.11.1)| Length = 784 Score = 65.9 bits (159), Expect = 1e-10 Identities = 40/110 (36%), Positives = 61/110 (55%), Gaps = 5/110 (4%) Frame = +2 Query: 35 STVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRIL 214 S GT Y+APEV++RR + AD WS GV ++ ML G PF+ D T+T+IL Sbjct: 263 SFCGTVEYMAPEVINRRGHS-MAADFWSLGVLMFEMLTGHLPFQGRDR----NDTMTQIL 317 Query: 215 SVQYSVPDYVRISMECRHLLSRIFVANPEQRI-----TIQEIKNHPWFLK 349 + S+P + ++ E + LL +F N + R+ ++EIK H +F K Sbjct: 318 KAKLSMPHF--LTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAK 365 Score = 55.8 bits (133), Expect = 1e-07 Identities = 38/128 (29%), Positives = 67/128 (52%), Gaps = 8/128 (6%) Frame = +2 Query: 47 TPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFE-DPDEPKNFRKTITRILSVQ 223 T ++APEVL ++ YD + DVWS GV L+ ML G PF P++ + + + R+ + Sbjct: 614 TAQFVAPEVLRKQGYD-RSCDVWSLGVLLHTMLTGCTPFAMGPNDTPD--QILQRVGDGK 670 Query: 224 YSV--PDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWF-----LKNLPIEMTDEYQ 382 S+ P + IS E + L+ ++ +P +R+T ++ H W L + PI+ + Sbjct: 671 ISMTHPVWDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQSEQVGE 730 Query: 383 MSLHMVGV 406 + + V V Sbjct: 731 LDMQNVKV 738
>NUAK1_HUMAN (O60285) NUAK family, SNF1-like kinase 1 (EC 2.7.11.1)| (AMPK-related protein kinase 5) Length = 661 Score = 65.9 bits (159), Expect = 1e-10 Identities = 34/99 (34%), Positives = 54/99 (54%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 G+P Y +PE+++ R Y G D W+ GV LY ++ G PF+ D + I +I S + Sbjct: 214 GSPLYASPEIVNGRPYRGPEVDSWALGVLLYTLVYGTMPFDGFDH----KNLIRQISSGE 269 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 Y P + R L+ + + NP++R TI++I NH W Sbjct: 270 YREPTQ---PSDARGLIRWMLMVNPDRRATIEDIANHWW 305
>KS6A1_HUMAN (Q15418) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 65.9 bits (159), Expect = 1e-10 Identities = 38/122 (31%), Positives = 67/122 (54%), Gaps = 4/122 (3%) Frame = +2 Query: 47 TPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFED--PDEPKNFRKTITRILSV 220 T ++APEVL R+ YD + D+WS G+ LY ML G PF + D P+ +TRI S Sbjct: 577 TANFVAPEVLKRQGYD-EGCDIWSLGILLYTMLAGYTPFANGPSDTPEEI---LTRIGSG 632 Query: 221 QYSVP--DYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPIEMTDEYQMSLH 394 ++++ ++ +S + L+S++ +P QR+T +++ HPW + + + L Sbjct: 633 KFTLSGGNWNTVSETAKDLVSKMLHVDPHQRLTAKQVLQHPWVTQKDKLPQSQLSHQDLQ 692 Query: 395 MV 400 +V Sbjct: 693 LV 694 Score = 62.8 bits (151), Expect = 8e-10 Identities = 41/120 (34%), Positives = 66/120 (55%), Gaps = 6/120 (5%) Frame = +2 Query: 2 SKSSVLHSQPK-STVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDE 178 SK ++ H + S GT Y+APEV++R+ + AD WS GV ++ ML G+ PF+ D Sbjct: 209 SKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHS-ADWWSYGVLMFEMLTGSLPFQGKDR 267 Query: 179 PKNFRKTITRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRI-----TIQEIKNHPWF 343 ++T+T IL + +P + +S E + LL +F NP R+ +EIK H ++ Sbjct: 268 ----KETMTLILKAKLGMPQF--LSTEAQSLLRALFKRNPANRLGSGPDGAEEIKRHVFY 321
>KRAC_DICDI (P54644) RAC-family serine/threonine-protein kinase homolog (EC| 2.7.11.1) Length = 444 Score = 65.5 bits (158), Expect = 1e-10 Identities = 42/101 (41%), Positives = 56/101 (55%), Gaps = 1/101 (0%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GTP Y+APEVL Y GK D WS G LY ML G PF + D + +RK I+ + Sbjct: 281 GTPEYLAPEVLQGNGY-GKQVDWWSFGSLLYEMLTGLPPFYNQDVQEMYRK----IMMEK 335 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQE-IKNHPWF 343 S P + IS + R LL ++ +PE+R+ IK HP+F Sbjct: 336 LSFPHF--ISPDARSLLEQLLERDPEKRLADPNLIKRHPFF 374
>TSSK4_MOUSE (Q9D411) Testis-specific serine/threonine-protein kinase 4 (EC| 2.7.11.1) (TSSK-4) (Testis-specific kinase 4) (TSK-4) Length = 328 Score = 65.5 bits (158), Expect = 1e-10 Identities = 36/114 (31%), Positives = 63/114 (55%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 G+ AY PE+L Y+ ++D WS GV LY ++V PF+D + K R+T + Sbjct: 200 GSFAYACPEILLGLPYNPFLSDTWSMGVILYTLVVARLPFDDTNLKKLLRET-----QKE 254 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPIEMTDEYQM 385 + P + IS EC++L+ ++ + +R TI ++ PW LK P + ++E ++ Sbjct: 255 VTFPANLTISQECKNLILQL-LRQSTKRATILDVLRDPWMLKFQPEQPSNEIRL 307
>GAD8_SCHPO (Q9P7J8) Serine/threonine-protein kinase gad8 (EC 2.7.11.1)| Length = 569 Score = 65.5 bits (158), Expect = 1e-10 Identities = 42/103 (40%), Positives = 55/103 (53%), Gaps = 3/103 (2%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GTP Y+APE+L Y KV D W+ GV LY M+ G PF D +N + +IL Sbjct: 390 GTPEYLAPELLLGHGYT-KVVDWWTLGVLLYEMITGLPPFYD----ENINEMYRKILQDP 444 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRI---TIQEIKNHPWF 343 PD I + + LLS + PE+R+ QEIKNHP+F Sbjct: 445 LRFPD--NIDEKAKDLLSGLLTRAPEKRLGSGGAQEIKNHPFF 485
>KPCD_RAT (P09215) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 673 Score = 65.5 bits (158), Expect = 1e-10 Identities = 39/102 (38%), Positives = 57/102 (55%), Gaps = 2/102 (1%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GTP YIAPE+L +Y V D WS GV LY ML+G PF DE + F S++ Sbjct: 508 GTPDYIAPEILQGLKYSFSV-DWWSFGVLLYEMLIGQSPFHGDDEDELFE-------SIR 559 Query: 224 YSVPDYVR-ISMECRHLLSRIFVANPEQRITIQ-EIKNHPWF 343 P Y R I+ E + ++ ++F +P +R+ + I+ HP+F Sbjct: 560 VDTPHYPRWITKESKDIMEKLFERDPAKRLGVTGNIRLHPFF 601
>KCC4_RAT (P13234) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) (Calspermin) Length = 474 Score = 65.5 bits (158), Expect = 1e-10 Identities = 35/105 (33%), Positives = 57/105 (54%), Gaps = 2/105 (1%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 K+ GTP Y APE+L Y G D+WS G+ Y++L G PF D + + RI Sbjct: 195 KTVCGTPGYCAPEILRGCAY-GPEVDMWSVGIITYILLCGFEPFYDE---RGDQFMFRRI 250 Query: 212 LSVQYSV--PDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 L+ +Y P + +S+ + L+ ++ V +P++R+T + HPW Sbjct: 251 LNCEYYFISPWWDEVSLNAKDLVKKLIVLDPKKRLTTFQALQHPW 295
>PIM1_FELCA (Q95LJ0) Proto-oncogene serine/threonine-protein kinase pim-1 (EC| 2.7.11.1) Length = 313 Score = 65.5 bits (158), Expect = 1e-10 Identities = 38/114 (33%), Positives = 53/114 (46%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GT Y PE + Y G+ A VWS G+ LY M+ G PFE +E ++ Sbjct: 203 GTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEE------------IIR 250 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPIEMTDEYQM 385 V R+S EC+HL+ P R + +EI+NHPW L + T E + Sbjct: 251 GQVFFRQRVSSECQHLIRWCLALRPSDRPSFEEIQNHPWMQDVLLPQETAEIHL 304
>KCC4_MOUSE (P08414) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) Length = 469 Score = 65.5 bits (158), Expect = 1e-10 Identities = 35/105 (33%), Positives = 57/105 (54%), Gaps = 2/105 (1%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 K+ GTP Y APE+L Y G D+WS G+ Y++L G PF D + + RI Sbjct: 195 KTVCGTPGYCAPEILRGCAY-GPEVDMWSVGIITYILLCGFEPFYDE---RGDQFMFRRI 250 Query: 212 LSVQYSV--PDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 L+ +Y P + +S+ + L+ ++ V +P++R+T + HPW Sbjct: 251 LNCEYYFISPWWDEVSLNAKDLVKKLIVLDPKKRLTTFQALQHPW 295
>IPL1_CANAL (Q59S66) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 530 Score = 65.5 bits (158), Expect = 1e-10 Identities = 34/105 (32%), Positives = 58/105 (55%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GT Y+ PE++ + +D V D+W+ G+ Y +LVG PFE N T +I V Sbjct: 425 GTLDYLPPEMIESKSHDFSV-DIWALGILCYELLVGKPPFE----AINRNITYEKIAKVD 479 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLP 358 P + ++ L+S++ V +P +R++++E+ NH W +KN P Sbjct: 480 IKYPS--NLDVDAIDLISKLVVKDPNKRLSLKEVLNHNWIIKNKP 522
>KIN1_YEAST (P13185) Protein kinase KIN1 (EC 2.7.11.1)| Length = 1064 Score = 65.1 bits (157), Expect = 2e-10 Identities = 36/126 (28%), Positives = 66/126 (52%), Gaps = 4/126 (3%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 G+ + APE+L Y G DVWS GV L+V++ G PF+D +N +I + Sbjct: 305 GSLYFAAPELLKANPYTGPEVDVWSFGVVLFVLVCGKVPFDD----ENSSVLHEKIKQGK 360 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNL----PIEMTDEYQMSL 391 P + +S+E LLS++ V +P++R T++++ H W ++ P + +++ Sbjct: 361 VEYPQH--LSIEVISLLSKMLVVDPKRRATLKQVVEHHWMVRGFNGPPPSYLPKRVPLTI 418 Query: 392 HMVGVN 409 M+ +N Sbjct: 419 EMLDIN 424
>KCC4_HUMAN (Q16566) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) Length = 473 Score = 65.1 bits (157), Expect = 2e-10 Identities = 35/105 (33%), Positives = 57/105 (54%), Gaps = 2/105 (1%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 K+ GTP Y APE+L Y G D+WS G+ Y++L G PF D + + RI Sbjct: 199 KTVCGTPGYCAPEILRGCAY-GPEVDMWSVGIITYILLCGFEPFYDE---RGDQFMFRRI 254 Query: 212 LSVQYSV--PDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 L+ +Y P + +S+ + L+ ++ V +P++R+T + HPW Sbjct: 255 LNCEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPW 299
>ATG1_NEUCR (Q7RX99) Serine/threonine-protein kinase atg-1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 932 Score = 65.1 bits (157), Expect = 2e-10 Identities = 37/118 (31%), Positives = 65/118 (55%) Frame = +2 Query: 23 SQPKSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTI 202 S ++ G+P Y+APE+L +YD K AD+WS G LY M+ G PF+ + + RK Sbjct: 226 SLAETLCGSPLYMAPEILRYEKYDAK-ADLWSVGTVLYEMVTGRPPFKASNHVELLRKIE 284 Query: 203 TRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPIEMTDE 376 + ++++ V S E + L+ + NP +RI+ +++ NHP + +P + D+ Sbjct: 285 SSGDVIKFTRESVV--SQEMKGLIRALLKKNPVERISFEDLFNHPVVTEPIPGLVEDD 340
>PIM3_XENLA (Q91822) Serine/threonine-protein kinase Pim-3 (EC 2.7.11.1)| (Pim-1) Length = 323 Score = 65.1 bits (157), Expect = 2e-10 Identities = 37/102 (36%), Positives = 47/102 (46%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GT Y PE + Y G+ A VWS GV LY M+ G PFE +E R R Sbjct: 204 GTRVYSPPEWVRYHRYHGRSATVWSLGVLLYDMVYGDIPFEQDEEIVRVRLCFRR----- 258 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLK 349 RIS EC+ L+ P R T+++I +HPW K Sbjct: 259 -------RISTECQQLIKWCLSLRPSDRPTLEQIFDHPWMCK 293
>PKH1_YEAST (Q03407) Serine/threonine-protein kinase PKH1 (EC 2.7.11.1)| (3-phosphoinositide-dependent protein kinase 1) Length = 766 Score = 64.7 bits (156), Expect = 2e-10 Identities = 36/109 (33%), Positives = 62/109 (56%) Frame = +2 Query: 17 LHSQPKSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRK 196 L+++ KS VGT Y++PE+L+ D + D+W+ G LY ML G PF+ +E F+K Sbjct: 290 LYAKSKSFVGTAEYVSPELLNDNYTDSR-CDIWAFGCILYQMLAGKPPFKAANEYLTFQK 348 Query: 197 TITRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWF 343 ++ +QY+ + L+ ++ V +P R+TI++IK H +F Sbjct: 349 ----VMKIQYAFT--AGFPQIVKDLVKKLLVRDPNDRLTIKQIKAHLFF 391
>KPSH2_HUMAN (Q96QS6) Serine/threonine-protein kinase H2 (EC 2.7.11.1) (PSK-H2)| Length = 385 Score = 64.7 bits (156), Expect = 2e-10 Identities = 33/105 (31%), Positives = 55/105 (52%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 K+ GTP YIAPEVL R+ Y V D+W+ GV Y +L G PF+D + + +RK + Sbjct: 220 KTLCGTPEYIAPEVLLRKPYTSAV-DMWALGVITYALLSGFLPFDDESQTRLYRKILKG- 277 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFL 346 Y+ + IS + + ++ + R++ + +HPW + Sbjct: 278 -KYNYTGEPWPSISHLAKDFIDKLLILEAGHRMSAGQALDHPWVI 321
>KOIA_SCHPO (Q9Y7J6) Putative serine/threonine-protein kinase C1778.10c (EC| 2.7.11.1) Length = 550 Score = 64.7 bits (156), Expect = 2e-10 Identities = 38/105 (36%), Positives = 58/105 (55%) Frame = +2 Query: 29 PKSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITR 208 P S VGT Y+APE+LSR+ K +D+W+ +Y M+VG+ PF + F+K Sbjct: 217 PSSFVGTAEYVAPELLSRQVVS-KSSDLWAFACVVYQMIVGSPPFHGSNPNNIFKK---- 271 Query: 209 ILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWF 343 I+S++Y +P + + L S +F P R T Q+IK P+F Sbjct: 272 IMSLEYELPKL--LPPDIVPLFSHLFRIQPSDRSTTQQIKQFPFF 314
>DAPK1_MOUSE (Q80YE7) Death-associated protein kinase 1 (EC 2.7.11.1) (DAP| kinase 1) Length = 1442 Score = 64.7 bits (156), Expect = 2e-10 Identities = 34/105 (32%), Positives = 59/105 (56%), Gaps = 2/105 (1%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 K+ GTP ++APE+++ G AD+WS GV Y++L GA PF + ++T+ + Sbjct: 175 KNIFGTPEFVAPEIVNYEPL-GLEADMWSIGVITYILLSGASPFLGDTK----QETLANV 229 Query: 212 LSVQYSVPD--YVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 +V Y + + S + + R+ V +P++R+TIQ+ HPW Sbjct: 230 SAVNYDFEEEFFRNTSTLAKDFIRRLLVKDPKKRMTIQDSLQHPW 274
>CHK1_XENLA (Q6DE87) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (xChk1| protein) Length = 474 Score = 64.7 bits (156), Expect = 2e-10 Identities = 34/100 (34%), Positives = 50/100 (50%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GT Y+APE++ R + DVWSCG+ L ML G P+ D+P + Sbjct: 169 GTLPYVAPELIKSRAFHADPVDVWSCGIVLTAMLAGELPW---DQPNEVCQEYCDWKEKN 225 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWF 343 + + + +IS LL ++ NP+ RITI +IK WF Sbjct: 226 HYLTPWKKISATPLALLCKMLTENPQSRITIPDIKKDRWF 265
>CDPK2_ORYSA (P53683) Calcium-dependent protein kinase, isoform 2 (EC 2.7.11.1)| (CDPK 2) Length = 533 Score = 64.7 bits (156), Expect = 2e-10 Identities = 37/103 (35%), Positives = 55/103 (53%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 + VG+ Y+APEVL RR Y GK DVWS GV LY++L G PF E F + Sbjct: 244 RDIVGSAYYVAPEVL-RRNY-GKEIDVWSAGVILYILLSGVPPFWAETEKGIFDAILQG- 300 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 + + + IS + L+ ++ +P++RIT ++ HPW Sbjct: 301 -EIDFESQPWPSISESAKDLVRKMLTQDPKKRITSAQVLQHPW 342
>AURKB_MOUSE (O70126) Serine/threonine-protein kinase 12 (EC 2.7.11.1)| (Aurora-related kinase 2) (Serine/threonine-protein kinase 5) (STK-1) (Aurora-B) Length = 345 Score = 64.7 bits (156), Expect = 2e-10 Identities = 34/107 (31%), Positives = 56/107 (52%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 K+ GT Y+ PE++ R ++ ++ D+W GV Y ++VG PFE P + +R+ + Sbjct: 236 KTMCGTLDYLPPEMIEGRMHN-EMVDLWCIGVLCYELMVGNPPFESPSHSETYRRIVKVD 294 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKN 352 L SVP + L+S++ NP QR+ + E+ HPW N Sbjct: 295 LKFPSSVPS------GAQDLISKLLKHNPWQRLPLAEVAAHPWVRAN 335
>TSSK6_MOUSE (Q925K9) Testis-specific serine/threonine-protein kinase 6 (EC| 2.7.11.1) (TSSK-6) (Small serine/threonine kinase) (Serine/threonine-protein kinase SSTK) Length = 273 Score = 64.3 bits (155), Expect = 3e-10 Identities = 35/99 (35%), Positives = 52/99 (52%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 G+ AY +PEVL YD K DVWS GV LYVM+ G PF+D D R+ +L Sbjct: 173 GSAAYASPEVLLGIPYDPKKYDVWSLGVVLYVMVTGCMPFDDSDIAGLPRRQKRGVL--- 229 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 PD + +S C+ L++ + +P R + ++ + W Sbjct: 230 --YPDGLELSERCKSLIAELLQFSPSARPSAGQVARNGW 266
>CBK1_YEAST (P53894) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1) (Cell| wall biosynthesis kinase) Length = 756 Score = 64.3 bits (155), Expect = 3e-10 Identities = 40/107 (37%), Positives = 60/107 (56%), Gaps = 4/107 (3%) Frame = +2 Query: 35 STVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRIL 214 STVGTP YIAPE+ + Y G+ D WS G +Y L+G PF + +RK + Sbjct: 570 STVGTPDYIAPEIFLYQGY-GQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQ 628 Query: 215 SVQYSVPDYVRISMECRHLLSRIFVANPEQRI----TIQEIKNHPWF 343 ++Q+ PD + IS E L+ R+ + + +QR+ EIK+HP+F Sbjct: 629 TLQF--PDDIHISYEAEDLIRRL-LTHADQRLGRHGGADEIKSHPFF 672
>CHK1_CHICK (Q8AYC9) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 64.3 bits (155), Expect = 3e-10 Identities = 39/108 (36%), Positives = 56/108 (51%), Gaps = 4/108 (3%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDP----DEPKNFRKTITRI 211 GT Y+APE+L R E+ + DVW+CGV L ML G P++ P E ++++ T Sbjct: 169 GTLPYVAPELLRRPEFRAEPVDVWACGVVLTAMLAGELPWDQPSDSCQEYSDWKERKT-- 226 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNL 355 Y P + +I LL +I NP RITI +IK W+ + L Sbjct: 227 ----YLAP-WRKIDSAPLALLHKILTENPTARITIPDIKKDRWYCRPL 269
>CDS1_SCHPO (Q09170) Serine/threonine-protein kinase cds1 (EC 2.7.11.1)| (Checkpoint kinase cds1) Length = 460 Score = 64.3 bits (155), Expect = 3e-10 Identities = 42/108 (38%), Positives = 54/108 (50%), Gaps = 8/108 (7%) Frame = +2 Query: 44 GTPAYIAPEVLSRRE------YDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIT 205 GT Y+APEVL + YD KV D+WS G LYVML + PF + K I Sbjct: 331 GTMGYLAPEVLKSKNVNLDGGYDDKV-DIWSLGCVLYVMLTASIPFASSSQAK----CIE 385 Query: 206 RILSVQYSVPDYVR--ISMECRHLLSRIFVANPEQRITIQEIKNHPWF 343 I Y + + IS E L++R+ NPE+RI+ E HPWF Sbjct: 386 LISKGAYPIEPLLENEISEEGIDLINRMLEINPEKRISESEALQHPWF 433
>KPCD1_MOUSE (Q62101) Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1)| (Protein kinase D) (Protein kinase C mu type) (nPKC-mu) Length = 918 Score = 64.3 bits (155), Expect = 3e-10 Identities = 36/104 (34%), Positives = 55/104 (52%), Gaps = 1/104 (0%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPF-EDPDEPKNFRKTITR 208 +S VGTPAY+APEVL + Y+ + D+WS GV +YV L G +PF ED D + Sbjct: 747 RSVVGTPAYLAPEVLRNKGYN-RSLDMWSVGVIIYVSLSGTFPFNEDEDIHDQIQNA--- 802 Query: 209 ILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 + Y + IS E L++ + +R ++ + +HPW Sbjct: 803 --AFMYPPNPWKEISHEAIDLINNLLQVKMRKRYSVDKTLSHPW 844
>KPCD1_HUMAN (Q15139) Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1)| (Protein kinase D) (Protein kinase C mu type) (nPKC-mu) Length = 912 Score = 64.3 bits (155), Expect = 3e-10 Identities = 36/104 (34%), Positives = 55/104 (52%), Gaps = 1/104 (0%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPF-EDPDEPKNFRKTITR 208 +S VGTPAY+APEVL + Y+ + D+WS GV +YV L G +PF ED D + Sbjct: 741 RSVVGTPAYLAPEVLRNKGYN-RSLDMWSVGVIIYVSLSGTFPFNEDEDIHDQIQNA--- 796 Query: 209 ILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 + Y + IS E L++ + +R ++ + +HPW Sbjct: 797 --AFMYPPNPWKEISHEAIDLINNLLQVKMRKRYSVDKTLSHPW 838
>KS6AA_XENLA (P10665) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 733 Score = 64.3 bits (155), Expect = 3e-10 Identities = 37/122 (30%), Positives = 67/122 (54%), Gaps = 4/122 (3%) Frame = +2 Query: 47 TPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDP--DEPKNFRKTITRILSV 220 T ++APEVL R+ YD + D+WS G+ LY ML G PF + D P+ + RI S Sbjct: 575 TANFVAPEVLKRQGYD-EGCDIWSLGILLYTMLAGYTPFANGLGDTPEEI---LARIGSG 630 Query: 221 QYSVP--DYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPIEMTDEYQMSLH 394 ++++ ++ +S + L+SR+ +P +R+T +++ H W K + + + +H Sbjct: 631 KFTLRGGNWNTVSAAAKDLVSRMLHVDPHKRLTAKQVLQHEWITKRDALPQSQLNRQDVH 690 Query: 395 MV 400 +V Sbjct: 691 LV 692 Score = 63.9 bits (154), Expect = 4e-10 Identities = 42/120 (35%), Positives = 66/120 (55%), Gaps = 6/120 (5%) Frame = +2 Query: 2 SKSSVLHSQPK-STVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDE 178 SK ++ H + S GT Y+APEV++R+ + AD WS GV ++ ML G+ PF+ D Sbjct: 209 SKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHS-ADWWSYGVLMFEMLTGSLPFQGKDR 267 Query: 179 PKNFRKTITRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRI-----TIQEIKNHPWF 343 ++T+T IL + +P + +S E + LL +F NP R+ +EIK P+F Sbjct: 268 ----KETMTLILKAKLGMPQF--LSNEAQSLLRALFKRNPTNRLGSAMEGAEEIKRQPFF 321
>KAPB_YEAST (P06245) cAMP-dependent protein kinase type 2 (EC 2.7.11.11) (PKA| 2) Length = 380 Score = 64.3 bits (155), Expect = 3e-10 Identities = 41/106 (38%), Positives = 57/106 (53%), Gaps = 6/106 (5%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIT-RILSV 220 GTP YIAPEV++ + Y+ K D WS GV +Y ML G PF D K + K + +++ Sbjct: 227 GTPDYIAPEVITTKPYN-KSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYP 285 Query: 221 QYSVPDYVRISMECRHLLSRIFVANPEQRI-----TIQEIKNHPWF 343 Y PD V LLS++ A+ +RI ++IK HPWF Sbjct: 286 PYFHPDVV-------DLLSKLITADLTRRIGNLQSGSRDIKAHPWF 324
>CHK2_MOUSE (Q9Z265) Serine/threonine-protein kinase Chk2 (EC 2.7.11.1)| Length = 546 Score = 64.3 bits (155), Expect = 3e-10 Identities = 37/107 (34%), Positives = 59/107 (55%), Gaps = 4/107 (3%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDG--KVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIT 205 ++ GTP Y+APEVL G + D WS GV L++ L G PF + + + IT Sbjct: 386 RTLCGTPTYLAPEVLVSNGTAGYSRAVDCWSLGVILFICLSGYPPFSEHKTQVSLKDQIT 445 Query: 206 RILSVQYS-VPD-YVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 S +Y+ +P+ + +S E L+ ++ V +P+ R+T +E NHPW Sbjct: 446 ---SGKYNFIPEVWTDVSEEALDLVKKLLVVDPKARLTTEEALNHPW 489
>KIN2_YEAST (P13186) Serine/threonine-protein kinase KIN2 (EC 2.7.11.1)| Length = 1147 Score = 63.9 bits (154), Expect = 4e-10 Identities = 33/99 (33%), Positives = 55/99 (55%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 G+ + APE+L + Y G D+WS G+ LYV++ G PF+D +N +I + Sbjct: 284 GSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPFDD----ENSSILHEKIKKGK 339 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 P + +S+E LL+R+ V +P +R T++ + HPW Sbjct: 340 VDYPSH--LSIEVISLLTRMIVVDPLRRATLKNVVEHPW 376
>KS6A6_HUMAN (Q9UK32) Ribosomal protein S6 kinase alpha-6 (EC 2.7.11.1)| (S6K-alpha 6) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4) Length = 745 Score = 63.9 bits (154), Expect = 4e-10 Identities = 43/118 (36%), Positives = 64/118 (54%), Gaps = 4/118 (3%) Frame = +2 Query: 2 SKSSV-LHSQPKSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDE 178 SK SV + S GT Y+APEV++RR + + AD WS GV ++ ML G PF+ D Sbjct: 220 SKESVDQEKKAYSFCGTVEYMAPEVVNRRGHS-QSADWWSYGVLMFEMLTGTLPFQGKDR 278 Query: 179 PKNFRKTITRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRI---TIQEIKNHPWF 343 +T+ IL + +P + +S E + LL +F NP R+ ++EIK H +F Sbjct: 279 ----NETMNMILKAKLGMPQF--LSAEAQSLLRMLFKRNPANRLGSEGVEEIKRHLFF 330 Score = 57.0 bits (136), Expect = 4e-08 Identities = 36/102 (35%), Positives = 56/102 (54%), Gaps = 4/102 (3%) Frame = +2 Query: 47 TPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFED--PDEPKNFRKTITRILSV 220 T ++APEVL ++ YD D+WS GV Y ML G PF + D P+ + + RI + Sbjct: 585 TANFVAPEVLMQQGYDA-ACDIWSLGVLFYTMLAGYTPFANGPNDTPE---EILLRIGNG 640 Query: 221 QYSVP--DYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 ++S+ ++ IS + LLS + +P QR T ++I H W Sbjct: 641 KFSLSGGNWDNISDGAKDLLSHMLHMDPHQRYTAEQILKHSW 682
>KN8R_YEAST (P53739) Probable serine/threonine-protein kinase YNR047W (EC| 2.7.11.1) Length = 893 Score = 63.9 bits (154), Expect = 4e-10 Identities = 38/109 (34%), Positives = 57/109 (52%), Gaps = 4/109 (3%) Frame = +2 Query: 35 STVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRIL 214 S VGT YIAPEV+ + V D W+ G+ +Y ML G PF+ N +T T IL Sbjct: 676 SFVGTEEYIAPEVIRGNGHTAAV-DWWTLGILIYEMLFGFTPFKG----DNTNETFTNIL 730 Query: 215 SVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQ----EIKNHPWFLK 349 + S P+ IS C+ L+ ++ N +R+ + ++K HP+F K Sbjct: 731 KNEVSFPNNNEISRTCKDLIKKLLTKNESKRLGCKMGAADVKKHPFFKK 779
>KAPC_YEAST (P05986) cAMP-dependent protein kinase type 3 (EC 2.7.11.11) (PKA| 3) Length = 398 Score = 63.9 bits (154), Expect = 4e-10 Identities = 38/105 (36%), Positives = 56/105 (53%), Gaps = 5/105 (4%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 GTP YIAPEV+S + Y+ K D WS GV +Y ML G PF + N KT IL+ + Sbjct: 245 GTPDYIAPEVVSTKPYN-KSVDWWSFGVLIYEMLAGYTPFYN----SNTMKTYENILNAE 299 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRI-----TIQEIKNHPWF 343 P + + + LL ++ + +R+ +++KNHPWF Sbjct: 300 LKFPPF--FHPDAQDLLKKLITRDLSERLGNLQNGSEDVKNHPWF 342
>PIM1_MOUSE (P06803) Proto-oncogene serine/threonine-protein kinase Pim-1 (EC| 2.7.11.1) Length = 397 Score = 63.9 bits (154), Expect = 4e-10 Identities = 38/118 (32%), Positives = 53/118 (44%), Gaps = 4/118 (3%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDE----PKNFRKTITRI 211 GT Y PE + Y G+ A VWS G+ LY M+ G PFE +E FR+T Sbjct: 287 GTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIKGQVFFRQT---- 342 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPIEMTDEYQM 385 +S EC+HL+ P R + +EI+NHPW +L + E + Sbjct: 343 ------------VSSECQHLIKWCLSLRPSDRPSFEEIRNHPWMQGDLLPQAASEIHL 388
>CDPK3_ORYSA (P53684) Calcium-dependent protein kinase, isoform 11 (EC 2.7.11.1)| (CDPK 11) Length = 542 Score = 63.9 bits (154), Expect = 4e-10 Identities = 35/104 (33%), Positives = 54/104 (51%) Frame = +2 Query: 41 VGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSV 220 VG+P Y+APEVL +R G +DVWS GV LYV+L G PF + F + + Sbjct: 241 VGSPYYVAPEVLHKRY--GPESDVWSAGVILYVLLSGVPPFWAETQQGIFDAVLKG--HI 296 Query: 221 QYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKN 352 + + +IS + L+ ++ P +R+ E+ HPW +N Sbjct: 297 DFQSDPWPKISDSAKDLIRKMLSHCPSERLKAHEVLRHPWICEN 340
>LATS2_MOUSE (Q7TSJ6) Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large| tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein) Length = 1042 Score = 63.5 bits (153), Expect = 5e-10 Identities = 42/105 (40%), Positives = 59/105 (56%), Gaps = 2/105 (1%) Frame = +2 Query: 35 STVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRIL 214 S VGTP YIAPEVL R+ Y ++ D WS GV L+ MLVG PF P + K I Sbjct: 830 SLVGTPNYIAPEVLLRKGYT-QLCDWWSVGVILFEMLVGQPPFLAPTPTETQLKVINWES 888 Query: 215 SVQYSVPDYVRISMECRHLLSRIFVANPEQ--RITIQEIKNHPWF 343 ++ +P VR+S E R L++++ A + R ++K HP+F Sbjct: 889 TLH--IPTQVRLSAEARDLITKLCCAADCRLGRDGADDLKAHPFF 931
>PLK1_XENTR (P62205) Serine/threonine-protein kinase PLK1 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-1) (Plx1) Length = 598 Score = 63.5 bits (153), Expect = 5e-10 Identities = 38/104 (36%), Positives = 58/104 (55%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 K+ GTP YIAPEVL ++ + +V D+WS G +Y +LVG PF E ++T RI Sbjct: 200 KTLCGTPNYIAPEVLGKKGHSFEV-DIWSIGCIMYTLLVGKPPF----ETSCLKETYMRI 254 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWF 343 +YSVP + I+ L+ ++ + P R TI ++ N +F Sbjct: 255 KKNEYSVPKH--INPMATALIQKMLRSEPTSRPTIDDLLNDEFF 296
>PLK1_XENLA (P70032) Serine/threonine-protein kinase PLK1 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-1) (Plx1) Length = 598 Score = 63.5 bits (153), Expect = 5e-10 Identities = 37/104 (35%), Positives = 59/104 (56%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 K+ GTP YIAPEVL ++ + +V D+WS G +Y +LVG PF E ++T RI Sbjct: 200 KTLCGTPNYIAPEVLGKKGHSFEV-DIWSIGCIMYTLLVGKPPF----ETSCLKETYMRI 254 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWF 343 +YS+P + I+ L+ ++ ++P R TI ++ N +F Sbjct: 255 KKNEYSIPKH--INPVAAALIQKMLRSDPTSRPTIDDLLNDEFF 296
>KC61_SCHPO (Q9UU87) Probable serine/threonine-protein kinase C1919.01 (EC| 2.7.11.1) Length = 354 Score = 63.5 bits (153), Expect = 5e-10 Identities = 38/105 (36%), Positives = 53/105 (50%), Gaps = 2/105 (1%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSR--REYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIT 205 K GTPA++APE+ ++ GK D+WS GVTLYV+ +PF I Sbjct: 232 KPASGTPAFMAPELFDNELKKIKGKPLDIWSMGVTLYVIAFAEFPFNG----STILDMIN 287 Query: 206 RILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 I +P Y + + R LL R NPE+RITI+E+ P+ Sbjct: 288 VIKGKSLMIPAY--CNSDLRKLLERCLEKNPEKRITIEELLRDPF 330
>CBK1_ASHGO (Q754N7) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1)| Length = 719 Score = 63.5 bits (153), Expect = 5e-10 Identities = 40/105 (38%), Positives = 56/105 (53%), Gaps = 2/105 (1%) Frame = +2 Query: 35 STVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRIL 214 STVGTP YIAPE+ + Y G+ D WS G +Y L+G PF + +RK + Sbjct: 530 STVGTPDYIAPEIFLYQGY-GQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQ 588 Query: 215 SVQYSVPDYVRISMECRHLLSRIFVANPEQ--RITIQEIKNHPWF 343 ++ + PD + IS E L+ R+ E+ R EIKNHP+F Sbjct: 589 TLVF--PDDIHISYEAEDLIRRLLSHADERLGRHGANEIKNHPFF 631
>PHKG1_RABIT (P00518) Phosphorylase b kinase gamma catalytic chain, skeletal| muscle isoform (EC 2.7.11.19) (Phosphorylase kinase gamma subunit 1) Length = 386 Score = 63.5 bits (153), Expect = 5e-10 Identities = 35/109 (32%), Positives = 57/109 (52%), Gaps = 5/109 (4%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYD-----GKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRK 196 + GTP+Y+APE++ D GK D+WS GV +Y +L G+ PF + R Sbjct: 181 REVCGTPSYLAPEIIECSMNDNHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRM 240 Query: 197 TITRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWF 343 ++ + Q+ P++ S + L+SR V P++R T +E HP+F Sbjct: 241 IMSG--NYQFGSPEWDDYSDTVKDLVSRFLVVQPQKRYTAEEALAHPFF 287
>CDPK4_PLAYO (Q7RJG2) Calcium-dependent protein kinase 4 (EC 2.7.11.1)| Length = 527 Score = 63.5 bits (153), Expect = 5e-10 Identities = 35/103 (33%), Positives = 55/103 (53%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 K +GT YIAP+VL YD K D+WSCGV LY++L G PF +E +K T Sbjct: 228 KDKIGTAYYIAPDVL-HGTYDEK-CDIWSCGVILYILLSGCPPFNGSNEYDILKKVETG- 284 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 + +P + +IS + + L+ ++ + RI+ ++ H W Sbjct: 285 -KYTFDLPQFKKISDKAKDLIKKMLMYTSAVRISARDALEHEW 326
>CDPK4_PLABA (P62345) Calcium-dependent protein kinase 4 (EC 2.7.11.1) (PbCDPK4)| Length = 527 Score = 63.5 bits (153), Expect = 5e-10 Identities = 35/103 (33%), Positives = 55/103 (53%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 K +GT YIAP+VL YD K D+WSCGV LY++L G PF +E +K T Sbjct: 228 KDKIGTAYYIAPDVL-HGTYDEK-CDIWSCGVILYILLSGCPPFNGSNEYDILKKVETG- 284 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 + +P + +IS + + L+ ++ + RI+ ++ H W Sbjct: 285 -KYTFDLPQFKKISDKAKDLIKKMLMYTSAVRISARDALEHEW 326
>PHKG2_HUMAN (P15735) Phosphorylase b kinase gamma catalytic chain, testis/liver| isoform (EC 2.7.11.19) (PHK-gamma-T) (Phosphorylase kinase gamma subunit 2) (PSK-C3) Length = 406 Score = 63.5 bits (153), Expect = 5e-10 Identities = 35/105 (33%), Positives = 56/105 (53%), Gaps = 5/105 (4%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYD-----GKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITR 208 GTP Y+APE+L + GK D+W+CGV L+ +L G+ PF + R + Sbjct: 189 GTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEG 248 Query: 209 ILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWF 343 Q+S P++ S + L+SR+ +PE R+T ++ HP+F Sbjct: 249 --QYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTAEQALQHPFF 291
>KOK0_YEAST (Q12236) Probable serine/threonine-protein kinase YOL100W (EC| 2.7.11.1) Length = 1081 Score = 63.2 bits (152), Expect = 6e-10 Identities = 39/110 (35%), Positives = 64/110 (58%), Gaps = 1/110 (0%) Frame = +2 Query: 17 LHSQPKSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRK 196 L ++ KS VGT Y++PE+L+ D + D+W+ G L+ M+ G PF+ +E F+K Sbjct: 342 LSTRSKSFVGTAEYVSPELLNDSFTDYR-CDIWAFGCILFQMIAGKPPFKATNEYLTFQK 400 Query: 197 TITRILSVQYS-VPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWF 343 ++ VQY+ P + I R L+ +I V N ++R+TI +IK H +F Sbjct: 401 ----VMKVQYAFTPGFPLI---IRDLVKKILVKNLDRRLTISQIKEHHFF 443
>ATG1_MAGGR (Q52EB3) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 982 Score = 63.2 bits (152), Expect = 6e-10 Identities = 37/118 (31%), Positives = 60/118 (50%) Frame = +2 Query: 23 SQPKSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTI 202 S ++ G+P Y+APE+L YD K AD+WS G L+ M+VG PF + + RK Sbjct: 221 SLAETLCGSPLYMAPEILRYERYDAK-ADLWSVGTVLFEMIVGRPPFRASNHVELLRKIE 279 Query: 203 TRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLKNLPIEMTDE 376 +++ P IS E + L + NP +RI+ + HP + ++P + D+ Sbjct: 280 AAEDVIKF--PRETTISSEMKGLTRALLKRNPVERISFENFFAHPVIISSIPGLVEDD 335
>KPCD3_MOUSE (Q8K1Y2) Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein| kinase C nu type) (nPKC-nu) Length = 889 Score = 63.2 bits (152), Expect = 6e-10 Identities = 36/103 (34%), Positives = 57/103 (55%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 +S VGTPAY+APEVL + Y+ + D+WS GV +YV L G +PF + DE N + + Sbjct: 733 RSVVGTPAYLAPEVLRSKGYN-RSLDMWSVGVIVYVSLSGTFPFNE-DEDINDQ---IQN 787 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 + Y + IS E L++ + +R ++ + +HPW Sbjct: 788 AAFMYPPNPWREISSEAIDLINNLLQVKMRKRYSVDKSLSHPW 830
>CBK1_CANGA (Q6FP74) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1)| Length = 773 Score = 63.2 bits (152), Expect = 6e-10 Identities = 41/107 (38%), Positives = 60/107 (56%), Gaps = 4/107 (3%) Frame = +2 Query: 35 STVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRIL 214 STVGTP YIAPE+ + Y G+ D WS G +Y L+G PF + +RK + Sbjct: 584 STVGTPDYIAPEIFLYQGY-GQDCDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQ 642 Query: 215 SVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQ----EIKNHPWF 343 ++Q+ P+ V IS E L+ R+ + + QR+ Q EIK+HP+F Sbjct: 643 TLQF--PEDVHISYEAEDLIRRL-LTHSNQRLGRQGGADEIKSHPFF 686
>KPCD3_HUMAN (O94806) Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein| kinase C nu type) (nPKC-nu) (Protein kinase EPK2) Length = 890 Score = 62.8 bits (151), Expect = 8e-10 Identities = 36/103 (34%), Positives = 57/103 (55%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRI 211 +S VGTPAY+APEVL + Y+ + D+WS GV +YV L G +PF + DE N + + Sbjct: 734 RSVVGTPAYLAPEVLRSKGYNRSL-DMWSVGVIIYVSLSGTFPFNE-DEDINDQ---IQN 788 Query: 212 LSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPW 340 + Y + IS E L++ + +R ++ + +HPW Sbjct: 789 AAFMYPPNPWREISGEAIDLINNLLQVKMRKRYSVDKSLSHPW 831
>CHK1_USTMA (P0C198) Serine/threonine-protein kinase CHK1 (EC 2.7.11.1)| (Checkpoint kinase 1) Length = 662 Score = 62.8 bits (151), Expect = 8e-10 Identities = 35/100 (35%), Positives = 53/100 (53%) Frame = +2 Query: 44 GTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTITRILSVQ 223 G+ YIAPE ++ + Y G+ DVWS GV L+ MLVG+ P+++P + Sbjct: 232 GSLPYIAPE-MNGKPYRGEPVDVWSSGVVLFAMLVGSTPWDEPTSRSPEYSAYRTGKLFE 290 Query: 224 YSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWF 343 Y + RI + LL ++ PE+RIT + I+ H WF Sbjct: 291 YD--PWPRIPQDALSLLKKMMHPTPEKRITFEGIRRHRWF 328
>CDPK1_PLAFK (P62343) Calcium-dependent protein kinase 1 (EC 2.7.11.1) (PfCPK)| (PfCDPK1) Length = 523 Score = 62.8 bits (151), Expect = 8e-10 Identities = 41/109 (37%), Positives = 56/109 (51%), Gaps = 3/109 (2%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPF---EDPDEPKNFRKTI 202 + +GT YIAPEVL R++Y+ K DVWSCGV LY++L G PF D D K K Sbjct: 225 RDRLGTAYYIAPEVL-RKKYNEK-CDVWSCGVILYILLCGYPPFGGQNDQDIIKKVEKG- 281 Query: 203 TRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLK 349 + D+ IS E + L+ + + +RIT +E N W K Sbjct: 282 ----KYYFDFNDWKNISEEAKELIKLMLTYDYNKRITAKEALNSKWIKK 326
>CDPK1_PLAF7 (P62344) Calcium-dependent protein kinase 1 (EC 2.7.11.1)| Length = 523 Score = 62.8 bits (151), Expect = 8e-10 Identities = 41/109 (37%), Positives = 56/109 (51%), Gaps = 3/109 (2%) Frame = +2 Query: 32 KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLVGAYPF---EDPDEPKNFRKTI 202 + +GT YIAPEVL R++Y+ K DVWSCGV LY++L G PF D D K K Sbjct: 225 RDRLGTAYYIAPEVL-RKKYNEK-CDVWSCGVILYILLCGYPPFGGQNDQDIIKKVEKG- 281 Query: 203 TRILSVQYSVPDYVRISMECRHLLSRIFVANPEQRITIQEIKNHPWFLK 349 + D+ IS E + L+ + + +RIT +E N W K Sbjct: 282 ----KYYFDFNDWKNISEEAKELIKLMLTYDYNKRITAKEALNSKWIKK 326 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 89,603,730 Number of Sequences: 219361 Number of extensions: 1880043 Number of successful extensions: 8336 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 7009 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 7500 length of database: 80,573,946 effective HSP length: 107 effective length of database: 57,102,319 effective search space used: 5767334219 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
