ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | baal32c20 |
|---|---|
| Clone Library Name | barley_pub |
>HT1_ARATH (Q2MHE4) Serine/threonine-protein kinase HT1 (EC 2.7.11.1) (High| leaf temperature protein 1) Length = 390 Score = 97.8 bits (242), Expect = 3e-20 Identities = 41/89 (46%), Positives = 62/89 (69%) Frame = +1 Query: 55 VIEHKPYDHKADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 +I+ KPY K DV+SFGI+LWEL T +P++ +TP+QAA V +K RP +P + L Sbjct: 257 MIKEKPYTRKVDVYSFGIVLWELTTALLPFQGMTPVQAAFAVAEKNERPPLPASCQPALA 316 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAE 321 L+++CW ++P++RPDFS I+ L+K E Sbjct: 317 HLIKRCWSENPSKRPDFSNIVAVLEKYDE 345
>M3KSL_DROME (Q95UN8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase) (dMLK) (Protein slipper) Length = 1161 Score = 81.3 bits (199), Expect = 3e-15 Identities = 40/88 (45%), Positives = 52/88 (59%) Frame = +1 Query: 55 VIEHKPYDHKADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 VI Y +DV+S+G+LLWEL+TG+ PY+ PL A GV L IPK Sbjct: 316 VISVSTYSKFSDVWSYGVLLWELITGETPYKGFDPLSVAYGVAVNTLTLPIPKTCPETWG 375 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIA 318 L++ CWQ DP +RP F EIL+ L+ IA Sbjct: 376 ALMKSCWQTDPHKRPGFKEILKQLESIA 403
>M3K11_HUMAN (Q16584) Mitogen-activated protein kinase kinase kinase 11 (EC| 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase) Length = 847 Score = 80.1 bits (196), Expect = 6e-15 Identities = 38/91 (41%), Positives = 53/91 (58%) Frame = +1 Query: 55 VIEHKPYDHKADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 VI+ + +DV+SFG+LLWELLTG++PY + L A GV L IP Sbjct: 293 VIKASTFSKGSDVWSFGVLLWELLTGEVPYRGIDCLAVAYGVAVNKLTLPIPSTCPEPFA 352 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEEV 327 +L+ CW QDP RPDF+ IL+ L+ + +V Sbjct: 353 QLMADCWAQDPHRRPDFASILQQLEALEAQV 383
>M3K10_HUMAN (Q02779) Mitogen-activated protein kinase kinase kinase 10 (EC| 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST) Length = 954 Score = 79.0 bits (193), Expect = 1e-14 Identities = 38/89 (42%), Positives = 50/89 (56%) Frame = +1 Query: 55 VIEHKPYDHKADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 VI + +DV+SFG+LLWELLTG++PY + L A GV L IP Sbjct: 274 VIRLSLFSKSSDVWSFGVLLWELLTGEVPYREIDALAVAYGVAMNKLTLPIPSTCPEPFA 333 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAE 321 LL++CW DP RPDF IL+ L+ I + Sbjct: 334 RLLEECWDPDPHGRPDFGSILKRLEVIEQ 362
>KYK2_DICDI (P18161) Tyrosine-protein kinase 2 (EC 2.7.10.2) (Fragment)| Length = 410 Score = 77.8 bits (190), Expect = 3e-14 Identities = 35/82 (42%), Positives = 52/82 (63%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKC 252 Y K DV+ F +++WE+LTG+IP+ L Q + V GLRP IP+ +L LL +C Sbjct: 287 YSEKVDVYCFSLVVWEILTGEIPFSDLDGSQRSAQVAYAGLRPPIPEYCDPELKLLLTQC 346 Query: 253 WQQDPAERPDFSEILEALKKIA 318 W+ DP +RP F+ I+ LK+I+ Sbjct: 347 WEADPNDRPPFTYIVNKLKEIS 368
>M3KL4_HUMAN (Q5TCX8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase 4) Length = 1036 Score = 77.4 bits (189), Expect = 4e-14 Identities = 39/94 (41%), Positives = 54/94 (57%) Frame = +1 Query: 55 VIEHKPYDHKADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 VI+ + +D++S+G+LLWELLTG++PY + L A GV L IP Sbjct: 315 VIKSSLFSKGSDIWSYGVLLWELLTGEVPYRGIDGLAVAYGVAVNKLTLPIPSTCPEPFA 374 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEEVGDE 336 +L+++CWQQDP RP F+ ILE L I V E Sbjct: 375 KLMKECWQQDPHIRPSFALILEQLTAIEGAVMTE 408
>MLTK_MOUSE (Q9ESL4) Mitogen-activated protein kinase kinase kinase MLT (EC| 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper-and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) ( Length = 802 Score = 77.0 bits (188), Expect = 5e-14 Identities = 34/90 (37%), Positives = 55/90 (61%) Frame = +1 Query: 55 VIEHKPYDHKADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 VI+ P D +S+G++LWE+LT ++P++ L LQ A VV+K R TIP + Sbjct: 177 VIQSLPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFA 236 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEE 324 ELL +CW+ D +RP F +I+ L+ ++ + Sbjct: 237 ELLHQCWEADAKKRPSFKQIISILESMSND 266
>MLTK_HUMAN (Q9NYL2) Mitogen-activated protein kinase kinase kinase MLT (EC| 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper-and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase Length = 800 Score = 77.0 bits (188), Expect = 5e-14 Identities = 34/90 (37%), Positives = 55/90 (61%) Frame = +1 Query: 55 VIEHKPYDHKADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 VI+ P D +S+G++LWE+LT ++P++ L LQ A VV+K R TIP + Sbjct: 177 VIQSLPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFA 236 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEE 324 ELL +CW+ D +RP F +I+ L+ ++ + Sbjct: 237 ELLHQCWEADAKKRPSFKQIISILESMSND 266
>M3K9_HUMAN (P80192) Mitogen-activated protein kinase kinase kinase 9 (EC| 2.7.11.25) (Mixed lineage kinase 1) Length = 1104 Score = 74.3 bits (181), Expect = 3e-13 Identities = 35/89 (39%), Positives = 49/89 (55%) Frame = +1 Query: 55 VIEHKPYDHKADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 VI + +DV+S+G+LLWELLTG++P+ + L A GV L IP Sbjct: 320 VIRASMFSKGSDVWSYGVLLWELLTGEVPFRGIDGLAVAYGVAMNKLALPIPSTCPEPFA 379 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAE 321 +L++ CW DP RP F+ IL+ L I E Sbjct: 380 KLMEDCWNPDPHSRPSFTNILDQLTTIEE 408
>FGFR4_RAT (Q498D6) Fibroblast growth factor receptor 4 precursor (EC| 2.7.10.1) (FGFR-4) Length = 800 Score = 73.2 bits (178), Expect = 7e-13 Identities = 35/90 (38%), Positives = 59/90 (65%), Gaps = 1/90 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y H++DV+SFGILLWE+ T G PY + P++ ++++G R P N ++L L+++ Sbjct: 664 YTHQSDVWSFGILLWEIFTLGGSPYPGI-PVEELFSLLREGHRMERPPNCPSELYGLMRE 722 Query: 250 CWQQDPAERPDFSEILEALKKIAEEVGDEH 339 CW P++RP F +++EAL K+ V +E+ Sbjct: 723 CWHAAPSQRPTFKQLVEALDKVLLAVSEEY 752
>YR831_MIMIV (Q7T6Y2) Putative serine/threonine-protein kinase/receptor R831| precursor (EC 2.7.11.1) Length = 1624 Score = 73.2 bits (178), Expect = 7e-13 Identities = 33/90 (36%), Positives = 57/90 (63%) Frame = +1 Query: 55 VIEHKPYDHKADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 VI + Y KADVFSFG+++WE+LTGK P+ ++ ++ +++ G RP IP + + Sbjct: 1531 VIRGEKYCEKADVFSFGVVMWEVLTGKEPFAECNFMKVSLDILEGG-RPIIPSDCPHEFA 1589 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEE 324 +L++KCW +RP +E+++ L I E+ Sbjct: 1590 KLIKKCWHAKAHKRPTMTEVVQQLMLITEQ 1619 Score = 72.4 bits (176), Expect = 1e-12 Identities = 36/81 (44%), Positives = 50/81 (61%), Gaps = 4/81 (4%) Frame = +1 Query: 85 ADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNA----HAKLTELLQKC 252 ADV+SFGI+LWELLT + PY+ +TP AV V++ G+RP I A + +L+++C Sbjct: 968 ADVYSFGIILWELLTREQPYKGMTPAAIAVSVIRDGMRPPISDEAVTAHSIEYIDLIKQC 1027 Query: 253 WQQDPAERPDFSEILEALKKI 315 W D RP F EI+ L I Sbjct: 1028 WHSDTIIRPTFLEIMTRLSNI 1048
>ILK1_HUMAN (Q13418) Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59| kDa serine/threonine-protein kinase) (p59ILK) Length = 452 Score = 72.8 bits (177), Expect = 9e-13 Identities = 34/92 (36%), Positives = 59/92 (64%), Gaps = 3/92 (3%) Frame = +1 Query: 58 IEHKPYD---HKADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAK 228 ++ KP D AD++SF +LLWEL+T ++P+ L+ ++ + V +GLRPTIP Sbjct: 361 LQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPH 420 Query: 229 LTELLQKCWQQDPAERPDFSEILEALKKIAEE 324 + +L++ C +DPA+RP F I+ L+K+ ++ Sbjct: 421 VCKLMKICMNEDPAKRPKFDMIVPILEKMQDK 452
>ILK_MOUSE (O55222) Integrin-linked protein kinase (EC 2.7.11.1)| Length = 452 Score = 72.4 bits (176), Expect = 1e-12 Identities = 33/92 (35%), Positives = 59/92 (64%), Gaps = 3/92 (3%) Frame = +1 Query: 58 IEHKPYD---HKADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAK 228 ++ KP D AD++SF +LLWEL+T ++P+ L+ ++ + V +GLRPT+P Sbjct: 361 LQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTVPPGISPH 420 Query: 229 LTELLQKCWQQDPAERPDFSEILEALKKIAEE 324 + +L++ C +DPA+RP F I+ L+K+ ++ Sbjct: 421 VCKLMKICMNEDPAKRPKFDMIVPILEKMQDK 452
>CTR1_ARATH (Q05609) Serine/threonine-protein kinase CTR1 (EC 2.7.11.1)| Length = 821 Score = 71.6 bits (174), Expect = 2e-12 Identities = 31/87 (35%), Positives = 54/87 (62%) Frame = +1 Query: 55 VIEHKPYDHKADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 V+ +P + K+DV+SFG++LWEL T + P+ L P Q V K R IP+N + ++ Sbjct: 722 VLRDEPSNEKSDVYSFGVILWELATLQQPWGNLNPAQVVAAVGFKCKRLEIPRNLNPQVA 781 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKI 315 +++ CW +P +RP F+ I++ L+ + Sbjct: 782 AIIEGCWTNEPWKRPSFATIMDLLRPL 808
>CSK_CHICK (P41239) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| Length = 450 Score = 70.9 bits (172), Expect = 3e-12 Identities = 36/90 (40%), Positives = 55/90 (61%), Gaps = 1/90 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 + K + K+DV+SFGILLWE+ + G++PY + PL+ V V+KG + P A + Sbjct: 358 LREKKFSTKSDVWSFGILLWEIYSFGRVPYPRI-PLKDVVPRVEKGYKMDPPDGCPAIVY 416 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEE 324 E+++KCW DP RP F ++ E L I E+ Sbjct: 417 EVMKKCWTLDPGHRPSFHQLREQLVHIKEK 446
>FGFR4_HUMAN (P22455) Fibroblast growth factor receptor 4 precursor (EC| 2.7.10.1) (FGFR-4) (CD334 antigen) Length = 802 Score = 70.5 bits (171), Expect = 4e-12 Identities = 34/90 (37%), Positives = 58/90 (64%), Gaps = 1/90 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y H++DV+SFGILLWE+ T G PY + P++ ++++G R P + +L L+++ Sbjct: 666 YTHQSDVWSFGILLWEIFTLGGSPYPGI-PVEELFSLLREGHRMDRPPHCPPELYGLMRE 724 Query: 250 CWQQDPAERPDFSEILEALKKIAEEVGDEH 339 CW P++RP F +++EAL K+ V +E+ Sbjct: 725 CWHAAPSQRPTFKQLVEALDKVLLAVSEEY 754
>FGFR4_MOUSE (Q03142) Fibroblast growth factor receptor 4 precursor (EC| 2.7.10.1) (FGFR-4) (Protein-tyrosine kinase receptor MPK-11) Length = 799 Score = 70.1 bits (170), Expect = 6e-12 Identities = 34/90 (37%), Positives = 58/90 (64%), Gaps = 1/90 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y H++DV+SF ILLWE+ T G PY + P++ ++++G R P N ++L L+++ Sbjct: 663 YTHQSDVWSFEILLWEIFTLGGSPYPGI-PVEELFSLLREGHRMERPPNCPSELYGLMRE 721 Query: 250 CWQQDPAERPDFSEILEALKKIAEEVGDEH 339 CW P++RP F +++EAL K+ V +E+ Sbjct: 722 CWHAAPSQRPTFKQLVEALDKVLLAVSEEY 751
>M3K12_RAT (Q63796) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 69.7 bits (169), Expect = 8e-12 Identities = 32/81 (39%), Positives = 47/81 (58%) Frame = +1 Query: 55 VIEHKPYDHKADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 VI ++P K D++SFG++LWELLTG+IPY+ + GV L +P + Sbjct: 314 VIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPDGFK 373 Query: 235 ELLQKCWQQDPAERPDFSEIL 297 LL++CW + P RP F +IL Sbjct: 374 ILLRQCWNRKPRNRPSFRQIL 394
>TXK_HUMAN (P42681) Tyrosine-protein kinase TXK (EC 2.7.10.2)| Length = 527 Score = 69.7 bits (169), Expect = 8e-12 Identities = 35/84 (41%), Positives = 53/84 (63%), Gaps = 1/84 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y K+DV+SFG+L+WE+ T GK+P+E + LQ V + +G R P A + E++ Sbjct: 443 YSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQV-VEAISEGFRLYRPHLAPMSIYEVMYS 501 Query: 250 CWQQDPAERPDFSEILEALKKIAE 321 CW + P RP F+E+L A+ +IAE Sbjct: 502 CWHEKPEGRPTFAELLRAVTEIAE 525
>ILK2_HUMAN (P57043) Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2)| Length = 452 Score = 69.7 bits (169), Expect = 8e-12 Identities = 33/92 (35%), Positives = 58/92 (63%), Gaps = 3/92 (3%) Frame = +1 Query: 58 IEHKPYD---HKADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAK 228 ++ KP D AD++SF +LLWEL+T ++P+ L+ ++ + V +GLRPTIP Sbjct: 361 LQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPH 420 Query: 229 LTELLQKCWQQDPAERPDFSEILEALKKIAEE 324 + +L++ C +DPA+R F I+ L+K+ ++ Sbjct: 421 VCKLMKICMNEDPAKRSKFDMIVPILEKMQDK 452
>TNI3K_RAT (Q7TQP6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 834 Score = 69.3 bits (168), Expect = 1e-11 Identities = 33/80 (41%), Positives = 49/80 (61%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKC 252 Y KADVFS+ + LWELLTG+IP+ +L P AA + +RP I + ++ LL + Sbjct: 641 YTIKADVFSYSLCLWELLTGEIPFAHLKPAAAAADMAYHHIRPPIGYSIPKPISSLLIRG 700 Query: 253 WQQDPAERPDFSEILEALKK 312 W P RP+FSE++ L++ Sbjct: 701 WNACPEGRPEFSEVVSKLEE 720
>M3K12_MOUSE (Q60700) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 69.3 bits (168), Expect = 1e-11 Identities = 32/81 (39%), Positives = 46/81 (56%) Frame = +1 Query: 55 VIEHKPYDHKADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 VI ++P K D++SFG++LWELLTG+IPY+ + GV L +P + Sbjct: 314 VIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPDGFK 373 Query: 235 ELLQKCWQQDPAERPDFSEIL 297 LL++CW P RP F +IL Sbjct: 374 ILLRQCWNSKPRNRPSFRQIL 394
>M3K12_HUMAN (Q12852) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 859 Score = 69.3 bits (168), Expect = 1e-11 Identities = 32/81 (39%), Positives = 46/81 (56%) Frame = +1 Query: 55 VIEHKPYDHKADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 VI ++P K D++SFG++LWELLTG+IPY+ + GV L +P + Sbjct: 281 VIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPDGFK 340 Query: 235 ELLQKCWQQDPAERPDFSEIL 297 LL++CW P RP F +IL Sbjct: 341 ILLRQCWNSKPRNRPSFRQIL 361
>TXK_MOUSE (P42682) Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18)| (Resting lymphocyte kinase) Length = 527 Score = 68.9 bits (167), Expect = 1e-11 Identities = 35/90 (38%), Positives = 53/90 (58%), Gaps = 1/90 (1%) Frame = +1 Query: 55 VIEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKL 231 V Y K+DV+SFG+L+WE+ T GK+P+E + LQ V + +G R P A + Sbjct: 437 VFHFNKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQV-VEAISQGFRLYRPHLAPMTI 495 Query: 232 TELLQKCWQQDPAERPDFSEILEALKKIAE 321 ++ CW + P RP F+E+L+ L +IAE Sbjct: 496 YRVMYSCWHESPKGRPTFAELLQVLTEIAE 525
>M3K7_HUMAN (O43318) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 606 Score = 68.9 bits (167), Expect = 1e-11 Identities = 31/85 (36%), Positives = 50/85 (58%), Gaps = 1/85 (1%) Frame = +1 Query: 55 VIEHKPYDHKADVFSFGILLWELLTGKIPYEYLT-PLQAAVGVVQKGLRPTIPKNAHAKL 231 V E Y K DVFS+GI+LWE++T + P++ + P + V G RP + KN + Sbjct: 200 VFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPI 259 Query: 232 TELLQKCWQQDPAERPDFSEILEAL 306 L+ +CW +DP++RP EI++ + Sbjct: 260 ESLMTRCWSKDPSQRPSMEEIVKIM 284
>M3K7_MOUSE (Q62073) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 579 Score = 68.9 bits (167), Expect = 1e-11 Identities = 31/85 (36%), Positives = 50/85 (58%), Gaps = 1/85 (1%) Frame = +1 Query: 55 VIEHKPYDHKADVFSFGILLWELLTGKIPYEYLT-PLQAAVGVVQKGLRPTIPKNAHAKL 231 V E Y K DVFS+GI+LWE++T + P++ + P + V G RP + KN + Sbjct: 200 VFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPI 259 Query: 232 TELLQKCWQQDPAERPDFSEILEAL 306 L+ +CW +DP++RP EI++ + Sbjct: 260 ESLMTRCWSKDPSQRPSMEEIVKIM 284
>TNI3K_MOUSE (Q5GIG6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 833 Score = 68.2 bits (165), Expect = 2e-11 Identities = 32/80 (40%), Positives = 48/80 (60%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKC 252 Y KADVFS+ + LWELL G+IP+ +L P AA + +RP I + ++ LL + Sbjct: 640 YTIKADVFSYALCLWELLIGEIPFAHLKPAAAAADMAYHHIRPPIGYSIPKPISSLLMRG 699 Query: 253 WQQDPAERPDFSEILEALKK 312 W P RP+FSE++ L++ Sbjct: 700 WNACPEGRPEFSEVVRKLEE 719
>TNI3K_HUMAN (Q59H18) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 936 Score = 67.8 bits (164), Expect = 3e-11 Identities = 32/80 (40%), Positives = 49/80 (61%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKC 252 Y KADVFS+ + LWE+LTG+IP+ +L P AA + +RP I + ++ LL + Sbjct: 743 YTIKADVFSYALCLWEILTGEIPFAHLKPAAAAADMAYHHIRPPIGYSIPKPISSLLIRG 802 Query: 253 WQQDPAERPDFSEILEALKK 312 W P RP+FSE++ L++ Sbjct: 803 WNACPEGRPEFSEVVMKLEE 822
>ITK_MOUSE (Q03526) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK) Length = 625 Score = 67.4 bits (163), Expect = 4e-11 Identities = 34/90 (37%), Positives = 54/90 (60%), Gaps = 1/90 (1%) Frame = +1 Query: 55 VIEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKL 231 V Y K+DV+SFG+L+WE+ + GKIPYE + + V + G R P+ A + Sbjct: 534 VFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEV-VEDISTGFRLYKPRLASCHV 592 Query: 232 TELLQKCWQQDPAERPDFSEILEALKKIAE 321 +++ CW++ P +RP FS++L L +IAE Sbjct: 593 YQIMNHCWKEKPEDRPPFSQLLSQLAEIAE 622
>ILK_CAVPO (P57044) Integrin-linked protein kinase (EC 2.7.11.1)| (Beta-integrin-linked kinase) Length = 451 Score = 66.6 bits (161), Expect = 6e-11 Identities = 33/92 (35%), Positives = 58/92 (63%), Gaps = 3/92 (3%) Frame = +1 Query: 58 IEHKPYD---HKADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAK 228 ++ KP D AD++SF +LLWEL+T ++P+ L+ ++ + V +G RPTIP Sbjct: 361 LQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEG-RPTIPPGISPH 419 Query: 229 LTELLQKCWQQDPAERPDFSEILEALKKIAEE 324 + +L++ C +DPA+RP F I+ L+K+ ++ Sbjct: 420 VCKLMKICMNEDPAKRPKFDMIVPILEKMQDK 451
>TEC_HUMAN (P42680) Tyrosine-protein kinase Tec (EC 2.7.10.2)| Length = 631 Score = 65.9 bits (159), Expect = 1e-10 Identities = 32/90 (35%), Positives = 55/90 (61%), Gaps = 1/90 (1%) Frame = +1 Query: 55 VIEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKL 231 V + + K+DV+SFG+L+WE+ T G++P+E T + V +V +G R PK A + Sbjct: 536 VFNYSRFSSKSDVWSFGVLMWEVFTEGRMPFEKYTNYEV-VTMVTRGHRLYQPKLASNYV 594 Query: 232 TELLQKCWQQDPAERPDFSEILEALKKIAE 321 E++ +CWQ+ P RP F ++L + ++ E Sbjct: 595 YEVMLRCWQEKPEGRPSFEDLLRTIDELVE 624
>PTK7_CHICK (Q91048) Tyrosine-protein kinase-like 7 precursor (Kinase-like| protein) Length = 1051 Score = 65.9 bits (159), Expect = 1e-10 Identities = 30/79 (37%), Positives = 49/79 (62%), Gaps = 1/79 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 + K+DV+SFG+L+WE+ T G++PY L + G+ + P+ ++LT+L+Q+ Sbjct: 964 FSTKSDVWSFGVLMWEVFTQGEMPYAPLADDEVLAGLKSGKTKLPQPEGCPSRLTKLMQR 1023 Query: 250 CWQQDPAERPDFSEILEAL 306 CW P +RP FSE+ AL Sbjct: 1024 CWAPSPKDRPSFSELAAAL 1042
>ITK_HUMAN (Q08881) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT) Length = 620 Score = 65.9 bits (159), Expect = 1e-10 Identities = 34/90 (37%), Positives = 53/90 (58%), Gaps = 1/90 (1%) Frame = +1 Query: 55 VIEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKL 231 V Y K+DV+SFG+L+WE+ + GKIPYE + + V + G R P+ A + Sbjct: 529 VFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEV-VEDISTGFRLYKPRLASTHV 587 Query: 232 TELLQKCWQQDPAERPDFSEILEALKKIAE 321 +++ CW++ P +RP FS +L L +IAE Sbjct: 588 YQIMNHCWKERPEDRPAFSRLLRQLAEIAE 617
>PHY1_CERPU (P25848) Light-sensor Protein kinase [Includes: Phytochrome; Protein| kinase (EC 2.7.11.1)] Length = 1307 Score = 65.9 bits (159), Expect = 1e-10 Identities = 30/79 (37%), Positives = 48/79 (60%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKC 252 Y K+DV+SFG++ +E+LTG +P+ +V +G+RP +P + +L L+ C Sbjct: 1205 YPLKSDVYSFGMVCYEVLTGDVPFPEEKNPNNVKRMVLEGVRPDLPAHCPIELKALITDC 1264 Query: 253 WQQDPAERPDFSEILEALK 309 W QDP +RP F+ I + LK Sbjct: 1265 WNQDPLKRPSFAVICQKLK 1283
>CSK_HUMAN (P41240) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| (Protein-tyrosine kinase CYL) Length = 450 Score = 65.5 bits (158), Expect = 1e-10 Identities = 33/87 (37%), Positives = 52/87 (59%), Gaps = 1/87 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 + K + K+DV+SFGILLWE+ + G++PY + PL+ V V+KG + P + Sbjct: 358 LREKKFSTKSDVWSFGILLWEIYSFGRVPYPRI-PLKDVVPRVEKGYKMDAPDGCPPAVY 416 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKI 315 E+++ CW D A RP F ++ E L+ I Sbjct: 417 EVMKNCWHLDAAMRPSFLQLREQLEHI 443
>KYK1_DICDI (P18160) Non-receptor tyrosine kinase spore lysis A (EC 2.7.10.2)| (Tyrosine-protein kinase 1) Length = 1584 Score = 65.5 bits (158), Expect = 1e-10 Identities = 29/81 (35%), Positives = 50/81 (61%) Frame = +1 Query: 82 KADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 261 K+DV+S+G++L+ELLT P + + P++ A + RP IP +K E+L +CW Sbjct: 1485 KSDVYSYGMVLFELLTSDEPQQDMKPMKMAHLAAYESYRPPIPLTTSSKWKEILTQCWDS 1544 Query: 262 DPAERPDFSEILEALKKIAEE 324 +P RP F +I+ LK++ ++ Sbjct: 1545 NPDSRPTFKQIIVHLKEMEDQ 1565
>ABL2_HUMAN (P42684) Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine| leukemia viral oncogene homolog 2) (Tyrosine kinase ARG) Length = 1182 Score = 65.1 bits (157), Expect = 2e-10 Identities = 35/100 (35%), Positives = 58/100 (58%), Gaps = 7/100 (7%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 + + + K+DV++FG+LLWE+ T G PY + L +++KG R P+ K+ Sbjct: 457 LAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGID-LSQVYDLLEKGYRMEQPEGCPPKVY 515 Query: 235 ELLQKCWQQDPAERPDFSEILEALK------KIAEEVGDE 336 EL++ CW+ PA+RP F+E +A + I+EEV +E Sbjct: 516 ELMRACWKWSPADRPSFAETHQAFETMFHDSSISEEVAEE 555
>M3K13_PONPY (Q5R8X7) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) Length = 966 Score = 64.7 bits (156), Expect = 2e-10 Identities = 32/91 (35%), Positives = 48/91 (52%) Frame = +1 Query: 55 VIEHKPYDHKADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 VI ++P K D++SFG++LWELLTG+IPY+ + GV L +P Sbjct: 324 VIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFK 383 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEEV 327 L+++ WQ P RP F + L L + +V Sbjct: 384 ILMKQTWQSKPRNRPSFRQTLMHLDIASADV 414
>M3K13_HUMAN (O43283) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase) Length = 966 Score = 64.7 bits (156), Expect = 2e-10 Identities = 32/91 (35%), Positives = 48/91 (52%) Frame = +1 Query: 55 VIEHKPYDHKADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 VI ++P K D++SFG++LWELLTG+IPY+ + GV L +P Sbjct: 324 VIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFK 383 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEEV 327 L+++ WQ P RP F + L L + +V Sbjct: 384 ILMKQTWQSKPRNRPSFRQTLMHLDIASADV 414
>BTK_CHICK (Q8JH64) Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton's| tyrosine kinase) Length = 657 Score = 64.3 bits (155), Expect = 3e-10 Identities = 32/91 (35%), Positives = 54/91 (59%), Gaps = 1/91 (1%) Frame = +1 Query: 55 VIEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKL 231 V+ + + K+DV+SFG+L+WE+ + GK+PYE + V+Q GLR P+ A ++ Sbjct: 566 VLLYSKFSSKSDVWSFGVLMWEVYSLGKMPYERFNNSETTEHVIQ-GLRLYRPQQASERV 624 Query: 232 TELLQKCWQQDPAERPDFSEILEALKKIAEE 324 ++ CW + ERP FS +L ++ I +E Sbjct: 625 YAIMYSCWHEKAEERPTFSALLGSIVDITDE 655
>CSK_RAT (P32577) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| Length = 450 Score = 64.3 bits (155), Expect = 3e-10 Identities = 32/87 (36%), Positives = 52/87 (59%), Gaps = 1/87 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 + K + K+DV+SFGILLWE+ + G++PY + PL+ V V+KG + P + Sbjct: 358 LREKKFSTKSDVWSFGILLWEIYSFGRVPYPRI-PLKDVVPRVEKGYKMDAPDGCPPAVY 416 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKI 315 ++++ CW D A RP F ++ E L+ I Sbjct: 417 DVMKNCWHLDAATRPTFLQLREQLEHI 443
>CEK3_CHICK (P18461) Tyrosine kinase receptor CEK3 precursor (EC 2.7.10.1)| Length = 823 Score = 63.9 bits (154), Expect = 4e-10 Identities = 30/82 (36%), Positives = 53/82 (64%), Gaps = 1/82 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y H++DV+SFG+L+WE+ T G PY + P++ ++++G R P N +L +++ Sbjct: 682 YTHQSDVWSFGVLMWEIFTLGGSPYPGI-PVEELFKLLKEGHRMDKPANCTNELYMMMRD 740 Query: 250 CWQQDPAERPDFSEILEALKKI 315 CWQ P++RP F +++E L +I Sbjct: 741 CWQAVPSQRPTFKQLVEDLDRI 762
>TEC_MOUSE (P24604) Tyrosine-protein kinase Tec (EC 2.7.10.2)| Length = 630 Score = 63.9 bits (154), Expect = 4e-10 Identities = 32/90 (35%), Positives = 54/90 (60%), Gaps = 1/90 (1%) Frame = +1 Query: 55 VIEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKL 231 V + + K+DV+SFG+L+WE+ T G++P+E T + V +V +G R PK A L Sbjct: 535 VFNYSRFSSKSDVWSFGVLMWEIFTEGRMPFEKNTNYEV-VTMVTRGHRLHRPKLATKYL 593 Query: 232 TELLQKCWQQDPAERPDFSEILEALKKIAE 321 E++ +CWQ+ P RP ++L + ++ E Sbjct: 594 YEVMLRCWQERPEGRPSLEDLLRTIDELVE 623
>RYK1_DROME (Q27324) Tyrosine-protein kinase Drl precursor (EC 2.7.10.1)| (Protein derailed) Length = 610 Score = 63.9 bits (154), Expect = 4e-10 Identities = 35/107 (32%), Positives = 57/107 (53%), Gaps = 1/107 (0%) Frame = +1 Query: 10 LGRREYDLTNFYLL*VIEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQ 186 LG EY + L ++ Y+ +DV+SFG+L+WE+ T GK+PY + P + ++ Sbjct: 501 LGDGEYRPIKWLSLEALQKSHYNEGSDVWSFGVLMWEMCTLGKLPYAEIDPYEME-HYLK 559 Query: 187 KGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFSEILEALKKIAEEV 327 G R P N +L ++ CW PAERP FS++ L + ++ Sbjct: 560 DGYRLAQPFNCPDELFTIMAYCWASMPAERPSFSQLQICLSEFHTQI 606
>VGFR1_RAT (P53767) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) Length = 1336 Score = 63.9 bits (154), Expect = 4e-10 Identities = 32/95 (33%), Positives = 57/95 (60%), Gaps = 1/95 (1%) Frame = +1 Query: 67 KPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELL 243 K Y K+DV+S+G+LLWE+ + G PY + + +++G+R P+ A ++ +++ Sbjct: 1074 KVYSTKSDVWSYGVLLWEIFSLGGSPYPGVQMDEDFCSRLKEGMRMRTPEYATPEIYQIM 1133 Query: 244 QKCWQQDPAERPDFSEILEALKKIAEEVGDEHDGK 348 CW +DP ERP F+E++E L + + + DGK Sbjct: 1134 LDCWHKDPKERPRFAELVEKLGDLL-QANVQQDGK 1167
>FGFR1_DROME (Q07407) Fibroblast growth factor receptor homolog 1 precursor (EC| 2.7.10.1) (Protein heartless) Length = 729 Score = 63.9 bits (154), Expect = 4e-10 Identities = 32/96 (33%), Positives = 54/96 (56%), Gaps = 1/96 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 ++ K YD K+DV+S+GILLWE++T G+ PY + + + G R P + Sbjct: 605 LQEKFYDSKSDVWSYGILLWEIMTYGQQPYPTIMSAEELYTYLMSGQRMEKPAKCSMNIY 664 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEEVGDEHD 342 L+++CW + +RP F+EI+E + K+ + D D Sbjct: 665 ILMRQCWHFNADDRPPFTEIVEYMDKLLQTKEDYLD 700
>MATK_HUMAN (P42679) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase) Length = 507 Score = 63.9 bits (154), Expect = 4e-10 Identities = 31/92 (33%), Positives = 52/92 (56%), Gaps = 1/92 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 ++H + K+DV+SFG+LLWE+ + G+ PY ++ L+ V+KG R P+ + Sbjct: 396 LKHGKFTSKSDVWSFGVLLWEVFSYGRAPYPKMS-LKEVSEAVEKGYRMEPPEGCPGPVH 454 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEEVG 330 L+ CW+ +PA RP F ++ E L + G Sbjct: 455 VLMSSCWEAEPARRPPFRKLAEKLARELRSAG 486
>VGFR1_MOUSE (P35969) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) (Embryonic receptor kinase 2) Length = 1333 Score = 63.9 bits (154), Expect = 4e-10 Identities = 32/95 (33%), Positives = 57/95 (60%), Gaps = 1/95 (1%) Frame = +1 Query: 67 KPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELL 243 K Y K+DV+S+G+LLWE+ + G PY + + +++G+R P+ A ++ +++ Sbjct: 1074 KVYSTKSDVWSYGVLLWEIFSLGGSPYPGVQMDEDFCSRLKEGMRMRTPEYATPEIYQIM 1133 Query: 244 QKCWQQDPAERPDFSEILEALKKIAEEVGDEHDGK 348 CW +DP ERP F+E++E L + + + DGK Sbjct: 1134 LDCWHKDPKERPRFAELVEKLGDLL-QANVQQDGK 1167
>ABL_MLVAB (P00521) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 746 Score = 63.5 bits (153), Expect = 5e-10 Identities = 33/96 (34%), Positives = 58/96 (60%), Gaps = 3/96 (3%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 + + + K+DV++FG+LLWE+ T G PY + L +++K R P+ K+ Sbjct: 297 LAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGID-LSQVYELLEKDYRMERPEGCPEKVY 355 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEE--VGDE 336 EL++ CWQ +P++RP F+EI +A + + +E + DE Sbjct: 356 ELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDE 391
>ABL1_MOUSE (P00520) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1123 Score = 63.5 bits (153), Expect = 5e-10 Identities = 33/96 (34%), Positives = 58/96 (60%), Gaps = 3/96 (3%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 + + + K+DV++FG+LLWE+ T G PY + L +++K R P+ K+ Sbjct: 411 LAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGID-LSQVYELLEKDYRMERPEGCPEKVY 469 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEE--VGDE 336 EL++ CWQ +P++RP F+EI +A + + +E + DE Sbjct: 470 ELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDE 505
>ABL1_HUMAN (P00519) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1130 Score = 63.5 bits (153), Expect = 5e-10 Identities = 33/96 (34%), Positives = 58/96 (60%), Gaps = 3/96 (3%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 + + + K+DV++FG+LLWE+ T G PY + L +++K R P+ K+ Sbjct: 411 LAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGID-LSQVYELLEKDYRMERPEGCPEKVY 469 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEE--VGDE 336 EL++ CWQ +P++RP F+EI +A + + +E + DE Sbjct: 470 ELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDE 505
>RON_HUMAN (Q04912) Macrophage-stimulating protein receptor precursor (EC| 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain] Length = 1400 Score = 63.5 bits (153), Expect = 5e-10 Identities = 33/87 (37%), Positives = 52/87 (59%), Gaps = 1/87 (1%) Frame = +1 Query: 82 KADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQ 258 K+DV+SFG+LLWELLT G PY ++ P + Q G R P+ L +++Q+CW+ Sbjct: 1267 KSDVWSFGVLLWELLTRGAPPYRHIDPFDLTHFLAQ-GRRLPQPEYCPDSLYQVMQQCWE 1325 Query: 259 QDPAERPDFSEILEALKKIAEEVGDEH 339 DPA RP F ++ +++I + +H Sbjct: 1326 ADPAVRPTFRVLVGEVEQIVSALLGDH 1352
>EPHAA_HUMAN (Q5JZY3) Ephrin type-A receptor 10 precursor (EC 2.7.10.1)| Length = 1008 Score = 63.2 bits (152), Expect = 7e-10 Identities = 32/85 (37%), Positives = 51/85 (60%), Gaps = 1/85 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 + +DV+SFGI++WE++ G+ PY ++ Q + V+ G R P+N L L+ Sbjct: 823 FSSASDVWSFGIIMWEVMAFGERPYWDMSG-QDVIKAVEDGFRLPPPRNCPNLLHRLMLD 881 Query: 250 CWQQDPAERPDFSEILEALKKIAEE 324 CWQ+DP ERP FS+I L K+ ++ Sbjct: 882 CWQKDPGERPRFSQIHSILSKMVQD 906
>MATK_MOUSE (P41242) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK) Length = 505 Score = 63.2 bits (152), Expect = 7e-10 Identities = 32/87 (36%), Positives = 50/87 (57%), Gaps = 1/87 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 + K+DV+SFG+LLWE+ + G+ PY ++ L+ V+KG R P + L+ Sbjct: 399 FSSKSDVWSFGVLLWEVFSYGRAPYPKMS-LKEVSEAVEKGYRMEPPDGCPGSVHTLMGS 457 Query: 250 CWQQDPAERPDFSEILEALKKIAEEVG 330 CW+ +PA RP F +I+E L + VG Sbjct: 458 CWEAEPARRPPFRKIVEKLGRELRSVG 484
>FGFR1_XENLA (P22182) Fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) Length = 812 Score = 63.2 bits (152), Expect = 7e-10 Identities = 30/82 (36%), Positives = 53/82 (64%), Gaps = 1/82 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y H++DV+SFG+LLWE+ T G PY + P++ ++++G R P N +L +++ Sbjct: 671 YTHQSDVWSFGVLLWEIFTLGGSPYPGV-PMEELFKLLKEGHRMDKPTNCTNELYMMMKD 729 Query: 250 CWQQDPAERPDFSEILEALKKI 315 CW P++RP F++++E L +I Sbjct: 730 CWHAMPSQRPTFNQLVEDLDRI 751
>BTKL_DROME (P08630) Tyrosine-protein kinase Btk29A (EC 2.7.10.2) (Dsrc28C)| Length = 786 Score = 62.8 bits (151), Expect = 9e-10 Identities = 30/94 (31%), Positives = 57/94 (60%), Gaps = 1/94 (1%) Frame = +1 Query: 55 VIEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKL 231 V+ + + K+DV+++G+L+WE+ T GK+PY L + V VQ+G+ PK+ ++ Sbjct: 694 VLNYTRFSSKSDVWAYGVLMWEIFTCGKMPYGRLKNTEV-VERVQRGIILEKPKSCAKEI 752 Query: 232 TELLQKCWQQDPAERPDFSEILEALKKIAEEVGD 333 ++++ CW P ERP F +++ L +A+ + D Sbjct: 753 YDVMKLCWSHGPEERPAFRVLMDQLALVAQTLTD 786
>FGFR1_MOUSE (P16092) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) Length = 822 Score = 62.8 bits (151), Expect = 9e-10 Identities = 30/82 (36%), Positives = 52/82 (63%), Gaps = 1/82 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y H++DV+SFG+LLWE+ T G PY + P++ ++++G R P N +L +++ Sbjct: 677 YTHQSDVWSFGVLLWEIFTLGGSPYPGV-PVEELFKLLKEGHRMDKPSNCTNELYMMMRD 735 Query: 250 CWQQDPAERPDFSEILEALKKI 315 CW P++RP F +++E L +I Sbjct: 736 CWHAVPSQRPTFKQLVEDLDRI 757
>FGFR1_HUMAN (P11362) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (Fms-like tyrosine kinase 2) (c-fgr) (CD331 antigen) Length = 822 Score = 62.8 bits (151), Expect = 9e-10 Identities = 30/82 (36%), Positives = 52/82 (63%), Gaps = 1/82 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y H++DV+SFG+LLWE+ T G PY + P++ ++++G R P N +L +++ Sbjct: 677 YTHQSDVWSFGVLLWEIFTLGGSPYPGV-PVEELFKLLKEGHRMDKPSNCTNELYMMMRD 735 Query: 250 CWQQDPAERPDFSEILEALKKI 315 CW P++RP F +++E L +I Sbjct: 736 CWHAVPSQRPTFKQLVEDLDRI 757
>KIT_BOVIN (P43481) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 977 Score = 62.8 bits (151), Expect = 9e-10 Identities = 28/85 (32%), Positives = 52/85 (61%), Gaps = 1/85 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y ++DV+S+GI LWEL + G PY + ++++G R P++A A++ ++++ Sbjct: 847 YTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKT 906 Query: 250 CWQQDPAERPDFSEILEALKKIAEE 324 CW DP +RP F +I++ ++K E Sbjct: 907 CWDADPLKRPTFKQIVQLIEKQISE 931
>RON_MOUSE (Q62190) Macrophage-stimulating protein receptor precursor (EC| 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating prote Length = 1378 Score = 62.8 bits (151), Expect = 9e-10 Identities = 35/88 (39%), Positives = 53/88 (60%), Gaps = 2/88 (2%) Frame = +1 Query: 82 KADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQ 258 K+DV+SFG+LLWELLT G PY ++ P + + Q G R P+ L ++ +CW+ Sbjct: 1244 KSDVWSFGVLLWELLTRGAPPYPHIDPFDLSHFLAQ-GRRLPQPEYCPDSLYHVMLRCWE 1302 Query: 259 QDPAERPDF-SEILEALKKIAEEVGDEH 339 DPA RP F + +LE + +A +GD + Sbjct: 1303 ADPAARPTFRALVLEVKQVVASLLGDHY 1330
>KIT_CAPHI (Q28317) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 978 Score = 62.8 bits (151), Expect = 9e-10 Identities = 28/85 (32%), Positives = 52/85 (61%), Gaps = 1/85 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y ++DV+S+GI LWEL + G PY + ++++G R P++A A++ ++++ Sbjct: 848 YTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKT 907 Query: 250 CWQQDPAERPDFSEILEALKKIAEE 324 CW DP +RP F +I++ ++K E Sbjct: 908 CWDADPLKRPTFKQIVQLIEKQISE 932
>FGFR1_CHICK (P21804) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) Length = 819 Score = 62.8 bits (151), Expect = 9e-10 Identities = 30/82 (36%), Positives = 52/82 (63%), Gaps = 1/82 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y H++DV+SFG+LLWE+ T G PY + P++ ++++G R P N +L +++ Sbjct: 675 YTHQSDVWSFGVLLWEIFTLGGSPYPGV-PVEELFKLLKEGHRMDKPSNCTNELYMMMRD 733 Query: 250 CWQQDPAERPDFSEILEALKKI 315 CW P++RP F +++E L +I Sbjct: 734 CWHAVPSQRPTFKQLVEDLDRI 755
>LCK_CHICK (P42683) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (Protein-tyrosine kinase C-TKL) (p56tk1) Length = 507 Score = 62.8 bits (151), Expect = 9e-10 Identities = 35/102 (34%), Positives = 61/102 (59%), Gaps = 1/102 (0%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I + + K+DV+SFGILL E++T G+IPY +T + + +++G R P N +L Sbjct: 410 INYGTFTIKSDVWSFGILLTEIVTYGRIPYPGMTNPEV-IQNLERGYRMPQPDNCPQELY 468 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEEVGDEHDGKHKDK 360 EL+ +CW++ P ERP F E +K + E+ +G+++ + Sbjct: 469 ELMMQCWKEQPEERPTF----EYMKSVLEDFFTATEGQYQQQ 506
>KIT_HUMAN (P10721) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen) Length = 976 Score = 62.8 bits (151), Expect = 9e-10 Identities = 28/85 (32%), Positives = 52/85 (61%), Gaps = 1/85 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y ++DV+S+GI LWEL + G PY + ++++G R P++A A++ ++++ Sbjct: 846 YTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKT 905 Query: 250 CWQQDPAERPDFSEILEALKKIAEE 324 CW DP +RP F +I++ ++K E Sbjct: 906 CWDADPLKRPTFKQIVQLIEKQISE 930
>FGFR3_HUMAN (P22607) Fibroblast growth factor receptor 3 precursor (EC| 2.7.10.1) (FGFR-3) (CD333 antigen) Length = 806 Score = 62.8 bits (151), Expect = 9e-10 Identities = 29/82 (35%), Positives = 52/82 (63%), Gaps = 1/82 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y H++DV+SFG+LLWE+ T G PY + P++ ++++G R P N L ++++ Sbjct: 671 YTHQSDVWSFGVLLWEIFTLGGSPYPGI-PVEELFKLLKEGHRMDKPANCTHDLYMIMRE 729 Query: 250 CWQQDPAERPDFSEILEALKKI 315 CW P++RP F +++E L ++ Sbjct: 730 CWHAAPSQRPTFKQLVEDLDRV 751
>FLK_RAT (P09760) Tyrosine-protein kinase FLK (EC 2.7.10.2) (Fragment)| Length = 323 Score = 62.8 bits (151), Expect = 9e-10 Identities = 32/86 (37%), Positives = 51/86 (59%), Gaps = 1/86 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y ++DV+SFGILLWE + G PY +T QA V ++G R + P+N ++ ++ K Sbjct: 238 YSSESDVWSFGILLWETFSLGVCPYPGMTNQQAREQV-ERGYRMSAPQNCPEEIFTIMMK 296 Query: 250 CWQQDPAERPDFSEILEALKKIAEEV 327 CW P RP FS++ + L I +++ Sbjct: 297 CWDYKPENRPKFSDLHKELTAIKKKI 322
>PGFRB_CANFA (Q6QNF3) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1103 Score = 62.4 bits (150), Expect = 1e-09 Identities = 31/85 (36%), Positives = 51/85 (60%), Gaps = 1/85 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y +DV+SFGILLWE+ T G PY L + +++G R P +A ++ E++QK Sbjct: 880 YTTLSDVWSFGILLWEIFTLGGTPYPELPMNEQFYNAIKRGYRMAQPAHASDEIYEIMQK 939 Query: 250 CWQQDPAERPDFSEILEALKKIAEE 324 CW++ RP FS+++ L+++ E Sbjct: 940 CWEEKFEIRPPFSQLVLLLERLLGE 964
>KIT_FELCA (Q28889) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 978 Score = 62.4 bits (150), Expect = 1e-09 Identities = 27/81 (33%), Positives = 51/81 (62%), Gaps = 1/81 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y ++DV+S+GI LWEL + G PY + ++++G R P++A A++ ++++ Sbjct: 847 YTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKT 906 Query: 250 CWQQDPAERPDFSEILEALKK 312 CW DP +RP F +I++ ++K Sbjct: 907 CWDADPLKRPTFKQIVQLIEK 927
>PGFRB_RAT (Q05030) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1097 Score = 62.4 bits (150), Expect = 1e-09 Identities = 31/85 (36%), Positives = 50/85 (58%), Gaps = 1/85 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y +DV+SFGILLWE+ T G PY L +++G R P +A ++ E++QK Sbjct: 879 YTTLSDVWSFGILLWEIFTLGGTPYPELPMNDQFYNAIKRGYRMAQPAHASDEIYEIMQK 938 Query: 250 CWQQDPAERPDFSEILEALKKIAEE 324 CW++ RP FS+++ L+++ E Sbjct: 939 CWEEKFETRPPFSQLVLLLERLLGE 963
>KIT_CANFA (O97799) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 975 Score = 62.4 bits (150), Expect = 1e-09 Identities = 27/81 (33%), Positives = 51/81 (62%), Gaps = 1/81 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y ++DV+S+GI LWEL + G PY + ++++G R P++A A++ ++++ Sbjct: 845 YTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKT 904 Query: 250 CWQQDPAERPDFSEILEALKK 312 CW DP +RP F +I++ ++K Sbjct: 905 CWDADPLKRPTFKQIVQLIEK 925
>VGFR1_HUMAN (P17948) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Vascular permeability factor receptor) (Tyrosine-protein kinase receptor FLT) (Flt-1) (Tyrosine-protein kinase FRT) (Fms-like tyrosine kinase 1) Length = 1338 Score = 62.4 bits (150), Expect = 1e-09 Identities = 31/95 (32%), Positives = 57/95 (60%), Gaps = 1/95 (1%) Frame = +1 Query: 67 KPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELL 243 K Y K+DV+S+G+LLWE+ + G PY + + +++G+R P+ + ++ +++ Sbjct: 1074 KIYSTKSDVWSYGVLLWEIFSLGGSPYPGVQMDEDFCSRLREGMRMRAPEYSTPEIYQIM 1133 Query: 244 QKCWQQDPAERPDFSEILEALKKIAEEVGDEHDGK 348 CW +DP ERP F+E++E L + + + DGK Sbjct: 1134 LDCWHRDPKERPRFAELVEKLGDLL-QANVQQDGK 1167
>KIT_FSVHZ (P04048) Tyrosine-protein kinase transforming protein kit (EC| 2.7.10.1) Length = 370 Score = 62.4 bits (150), Expect = 1e-09 Identities = 27/81 (33%), Positives = 51/81 (62%), Gaps = 1/81 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y ++DV+S+GI LWEL + G PY + ++++G R P++A A++ ++++ Sbjct: 284 YTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKT 343 Query: 250 CWQQDPAERPDFSEILEALKK 312 CW DP +RP F +I++ ++K Sbjct: 344 CWDADPLKRPTFKQIVQLIEK 364
>PGFRB_HUMAN (P09619) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) (CD140b antigen) Length = 1106 Score = 62.4 bits (150), Expect = 1e-09 Identities = 31/85 (36%), Positives = 51/85 (60%), Gaps = 1/85 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y +DV+SFGILLWE+ T G PY L + +++G R P +A ++ E++QK Sbjct: 880 YTTLSDVWSFGILLWEIFTLGGTPYPELPMNEQFYNAIKRGYRMAQPAHASDEIYEIMQK 939 Query: 250 CWQQDPAERPDFSEILEALKKIAEE 324 CW++ RP FS+++ L+++ E Sbjct: 940 CWEEKFEIRPPFSQLVLLLERLLGE 964
>CEK2_CHICK (P18460) Tyrosine kinase receptor CEK2 precursor (EC 2.7.10.1)| Length = 806 Score = 62.4 bits (150), Expect = 1e-09 Identities = 29/82 (35%), Positives = 52/82 (63%), Gaps = 1/82 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y H++DV+SFG+LLWE+ T G PY + P++ ++++G R P N L ++++ Sbjct: 665 YTHQSDVWSFGVLLWEIFTLGGSPYPGI-PVEELFKLLKEGHRMDKPANCTHDLYMIMRE 723 Query: 250 CWQQDPAERPDFSEILEALKKI 315 CW P++RP F +++E L ++ Sbjct: 724 CWHAVPSQRPTFKQLVEDLDRV 745
>PGFRB_MOUSE (P05622) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1098 Score = 62.4 bits (150), Expect = 1e-09 Identities = 31/85 (36%), Positives = 50/85 (58%), Gaps = 1/85 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y +DV+SFGILLWE+ T G PY L +++G R P +A ++ E++QK Sbjct: 879 YTTLSDVWSFGILLWEIFTLGGTPYPELPMNDQFYNAIKRGYRMAQPAHASDEIYEIMQK 938 Query: 250 CWQQDPAERPDFSEILEALKKIAEE 324 CW++ RP FS+++ L+++ E Sbjct: 939 CWEEKFETRPPFSQLVLLLERLLGE 963
>TIE2_BRARE (O73791) Tyrosine-protein kinase receptor Tie-2 precursor (EC| 2.7.10.1) Length = 1116 Score = 62.0 bits (149), Expect = 2e-09 Identities = 33/90 (36%), Positives = 55/90 (61%), Gaps = 1/90 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 + + Y +DV+S+G+LLWE+++ G PY +T + + G R P N ++ Sbjct: 1002 LNYSVYTTNSDVWSYGVLLWEVVSLGGTPYCGMTCAEL-YEKLPLGFRLEKPLNCDDEVY 1060 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEE 324 EL+Q+CW++ P ERP FS+IL +L ++ EE Sbjct: 1061 ELMQQCWREKPFERPSFSQILLSLGRMLEE 1090
>TIE1_BRARE (O73792) Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)| (Fragment) Length = 184 Score = 62.0 bits (149), Expect = 2e-09 Identities = 33/89 (37%), Positives = 54/89 (60%), Gaps = 1/89 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 + + Y K+DV+SFG+LLWE+++ G PY +T + + Q G R P+N ++ Sbjct: 71 LNYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQ-GYRMEQPRNCDDEVY 129 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAE 321 EL+++CW+ P ERP FS+I L ++ E Sbjct: 130 ELMRQCWRDRPYERPPFSQISVQLNRMQE 158
>FGFR2_MOUSE (P21803) Fibroblast growth factor receptor 2 precursor (EC| 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor) Length = 821 Score = 62.0 bits (149), Expect = 2e-09 Identities = 29/82 (35%), Positives = 52/82 (63%), Gaps = 1/82 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y H++DV+SFG+L+WE+ T G PY + P++ ++++G R P N +L +++ Sbjct: 680 YTHQSDVWSFGVLMWEIFTLGGSPYPGI-PVEELFKLLKEGHRMDKPTNCTNELYMMMRD 738 Query: 250 CWQQDPAERPDFSEILEALKKI 315 CW P++RP F +++E L +I Sbjct: 739 CWHAVPSQRPTFKQLVEDLDRI 760
>FGFR2_HUMAN (P21802) Fibroblast growth factor receptor 2 precursor (EC| 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor 2) (CD332 antigen) Length = 821 Score = 62.0 bits (149), Expect = 2e-09 Identities = 29/82 (35%), Positives = 52/82 (63%), Gaps = 1/82 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y H++DV+SFG+L+WE+ T G PY + P++ ++++G R P N +L +++ Sbjct: 680 YTHQSDVWSFGVLMWEIFTLGGSPYPGI-PVEELFKLLKEGHRMDKPANCTNELYMMMRD 738 Query: 250 CWQQDPAERPDFSEILEALKKI 315 CW P++RP F +++E L +I Sbjct: 739 CWHAVPSQRPTFKQLVEDLDRI 760
>KIT_MOUSE (P05532) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 975 Score = 62.0 bits (149), Expect = 2e-09 Identities = 26/81 (32%), Positives = 51/81 (62%), Gaps = 1/81 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y ++DV+S+GI LWEL + G PY + ++++G R P++A A++ ++++ Sbjct: 844 YTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMVSPEHAPAEMYDVMKT 903 Query: 250 CWQQDPAERPDFSEILEALKK 312 CW DP +RP F ++++ ++K Sbjct: 904 CWDADPLKRPTFKQVVQLIEK 924
>FGFR2_DROME (Q09147) Fibroblast growth factor receptor homolog 2 precursor (EC| 2.7.10.1) (Protein breathless) (dFGF-R1) Length = 1052 Score = 62.0 bits (149), Expect = 2e-09 Identities = 28/103 (27%), Positives = 55/103 (53%), Gaps = 1/103 (0%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 ++ K YD ++DV+S+G+LLWE++T G PY ++ + + G R P + Sbjct: 913 LQEKKYDSQSDVWSYGVLLWEIMTYGDQPYPHILSAEELYSYLITGQRMEKPAKCSLNIY 972 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEEVGDEHDGKHKDKS 363 ++++CW + RP F+E++E+ I ++ + + D S Sbjct: 973 VVMRQCWHFESCARPTFAELVESFDGILQQASSNPNDAYLDLS 1015
>MATK_RAT (P41243) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase BATK) Length = 467 Score = 62.0 bits (149), Expect = 2e-09 Identities = 31/87 (35%), Positives = 51/87 (58%), Gaps = 1/87 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 + K+DV+SFG+LLWE+ + G+ PY ++ L+ V+KG R P + + L+ Sbjct: 361 FSSKSDVWSFGVLLWEVFSYGRAPYPKMS-LKEVSEAVEKGYRMEPPDSCPGPVHTLMGS 419 Query: 250 CWQQDPAERPDFSEILEALKKIAEEVG 330 CW+ +P+ RP F +I+E L + VG Sbjct: 420 CWEAEPSRRPPFRKIVEKLGRELRSVG 446
>FER_HUMAN (P16591) Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2)| (p94-FER) (c-FER) Length = 822 Score = 61.6 bits (148), Expect = 2e-09 Identities = 32/86 (37%), Positives = 51/86 (59%), Gaps = 1/86 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y ++DV+SFGILLWE + G PY +T QA V ++G R + P++ +++++ K Sbjct: 737 YSSESDVWSFGILLWETFSLGVCPYPGMTNQQAREQV-ERGYRMSAPQHCPEDISKIMMK 795 Query: 250 CWQQDPAERPDFSEILEALKKIAEEV 327 CW P RP FSE+ + L I ++ Sbjct: 796 CWDYKPENRPKFSELQKELTIIKRKL 821
>EPHA7_MOUSE (Q61772) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1) Length = 998 Score = 61.6 bits (148), Expect = 2e-09 Identities = 30/87 (34%), Positives = 56/87 (64%), Gaps = 1/87 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I+++ + +DV+S+GI++WE+++ G+ PY ++ Q + +++G R P + A L Sbjct: 808 IQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSN-QDVIKAIEEGYRLPAPMDCPAGLH 866 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKI 315 +L+ CWQ+D AERP F +I+ L K+ Sbjct: 867 QLMLDCWQKDRAERPKFEQIVGILDKM 893
>CAD96_DROME (Q9VBW3) Tyrosine kinase receptor Cad96Ca precursor (EC 2.7.10.1)| (Cadherin 96Ca) (Tyrosine kinase receptor HD-14) Length = 773 Score = 61.6 bits (148), Expect = 2e-09 Identities = 30/79 (37%), Positives = 49/79 (62%), Gaps = 1/79 (1%) Frame = +1 Query: 82 KADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQ 258 K+D++SFGIL+WE++T G PY ++ + V+ G R P++ +L ++ CW Sbjct: 667 KSDIWSFGILMWEIVTLGSTPYPGISAADV-MRKVRDGYRLEKPEHCRRELYNIMYYCWS 725 Query: 259 QDPAERPDFSEILEALKKI 315 DP ERP F+EI++ L K+ Sbjct: 726 HDPQERPLFAEIIQMLDKL 744
>ERBB_AVIEU (P11273) Tyrosine-protein kinase transforming protein erbB (EC| 2.7.10.1) Length = 540 Score = 61.6 bits (148), Expect = 2e-09 Identities = 31/90 (34%), Positives = 50/90 (55%), Gaps = 1/90 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I H+ Y H++DV+S+G+ +WEL+T G PY+ + P V++KG R P + Sbjct: 306 ILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGI-PASEISSVLEKGERLPQPPICTIDVY 364 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEE 324 ++ KCW D RP F E++ K+A + Sbjct: 365 MIMVKCWMSDADSRPKFRELIAEFSKMARD 394
>TIE2_HUMAN (Q02763) Angiopoietin-1 receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen) Length = 1124 Score = 61.2 bits (147), Expect = 3e-09 Identities = 31/90 (34%), Positives = 56/90 (62%), Gaps = 1/90 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 + + Y +DV+S+G+LLWE+++ G PY +T + + Q G R P N ++ Sbjct: 1010 LNYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQ-GYRLEKPLNCDDEVY 1068 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEE 324 +L+++CW++ P ERP F++IL +L ++ EE Sbjct: 1069 DLMRQCWREKPYERPSFAQILVSLNRMLEE 1098
>RET_MOUSE (P35546) Proto-oncogene tyrosine-protein kinase receptor ret| precursor (EC 2.7.10.1) (C-ret) Length = 1115 Score = 61.2 bits (147), Expect = 3e-09 Identities = 32/91 (35%), Positives = 56/91 (61%), Gaps = 1/91 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y ++DV+SFG+LLWE++T G PY + P + +++ G R P N ++ L+ + Sbjct: 929 YTTQSDVWSFGVLLWEIVTLGGNPYPGIPP-ERLFNLLKTGHRMERPDNCSEEMYRLMLQ 987 Query: 250 CWQQDPAERPDFSEILEALKKIAEEVGDEHD 342 CW+Q+P +RP F++I + L+K+ + D D Sbjct: 988 CWKQEPDKRPVFADISKDLEKMMVKSRDYLD 1018
>FGFR2_XENLA (Q03364) Fibroblast growth factor receptor 2 precursor (EC| 2.7.10.1) (FGFR-2) Length = 813 Score = 61.2 bits (147), Expect = 3e-09 Identities = 29/82 (35%), Positives = 51/82 (62%), Gaps = 1/82 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y H++DV+SFG+L+WE+ T G PY + P++ ++++G R P N +L +++ Sbjct: 670 YTHQSDVWSFGVLMWEIFTLGGSPYPGI-PVEELFKLLKEGHRMDKPANCTNELYMMMRD 728 Query: 250 CWQQDPAERPDFSEILEALKKI 315 CW P+ RP F +++E L +I Sbjct: 729 CWHAIPSHRPTFKQLVEDLDRI 750
>TIE2_MOUSE (Q02858) Angiopoietin-1 receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen) Length = 1122 Score = 61.2 bits (147), Expect = 3e-09 Identities = 31/90 (34%), Positives = 56/90 (62%), Gaps = 1/90 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 + + Y +DV+S+G+LLWE+++ G PY +T + + Q G R P N ++ Sbjct: 1008 LNYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQ-GYRLEKPLNCDDEVY 1066 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEE 324 +L+++CW++ P ERP F++IL +L ++ EE Sbjct: 1067 DLMRQCWREKPYERPSFAQILVSLNRMLEE 1096
>TIE2_BOVIN (Q06807) Angiopoietin-1 receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TIE-2) (CD202b antigen) Length = 1125 Score = 61.2 bits (147), Expect = 3e-09 Identities = 31/90 (34%), Positives = 56/90 (62%), Gaps = 1/90 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 + + Y +DV+S+G+LLWE+++ G PY +T + + Q G R P N ++ Sbjct: 1011 LNYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQ-GYRLEKPLNCDDEVY 1069 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEE 324 +L+++CW++ P ERP F++IL +L ++ EE Sbjct: 1070 DLMRQCWREKPYERPSFAQILVSLNRMLEE 1099
>FYN_XIPHE (P27446) Proto-oncogene tyrosine-protein kinase FYN (EC 2.7.10.2)| (P59-FYN) Length = 536 Score = 61.2 bits (147), Expect = 3e-09 Identities = 34/75 (45%), Positives = 51/75 (68%), Gaps = 1/75 (1%) Frame = +1 Query: 82 KADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQ 258 K+DV+SFGILL EL+T G++PY + + + V++G R P++ A L EL+ +CW+ Sbjct: 445 KSDVWSFGILLTELVTKGRVPYPGMNNREV-LEQVERGYRMPCPQDCPASLHELMLQCWK 503 Query: 259 QDPAERPDFSEILEA 303 +DP ERP F E L+A Sbjct: 504 KDPEERPTF-EYLQA 517
>BTK_HUMAN (Q06187) Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton's| tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) Length = 658 Score = 60.8 bits (146), Expect = 4e-09 Identities = 30/91 (32%), Positives = 52/91 (57%), Gaps = 1/91 (1%) Frame = +1 Query: 55 VIEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKL 231 V+ + + K+D+++FG+L+WE+ + GK+PYE T + A + Q GLR P A K+ Sbjct: 567 VLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQ-GLRLYRPHLASEKV 625 Query: 232 TELLQKCWQQDPAERPDFSEILEALKKIAEE 324 ++ CW + ERP F +L + + +E Sbjct: 626 YTIMYSCWHEKADERPTFKILLSNILDVMDE 656
>FGFR3_MOUSE (Q61851) Fibroblast growth factor receptor 3 precursor (EC| 2.7.10.1) (FGFR-3) (Heparin-binding growth factor receptor) Length = 801 Score = 60.8 bits (146), Expect = 4e-09 Identities = 29/83 (34%), Positives = 52/83 (62%), Gaps = 2/83 (2%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT--GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQ 246 Y H++DV+SFG+LLWE+ T G PY + P++ ++++G R P + L +++ Sbjct: 665 YTHQSDVWSFGVLLWEIFTPGGPSPYPGI-PVEELFKLLKEGHRMDKPASCTHDLYMIMR 723 Query: 247 KCWQQDPAERPDFSEILEALKKI 315 +CW P++RP F +++E L +I Sbjct: 724 ECWHAVPSQRPTFKQLVEDLDRI 746
>RET_HUMAN (P07949) Proto-oncogene tyrosine-protein kinase receptor ret| precursor (EC 2.7.10.1) (C-ret) Length = 1114 Score = 60.8 bits (146), Expect = 4e-09 Identities = 30/82 (36%), Positives = 53/82 (64%), Gaps = 1/82 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y ++DV+SFG+LLWE++T G PY + P + +++ G R P N ++ L+ + Sbjct: 928 YTTQSDVWSFGVLLWEIVTLGGNPYPGIPP-ERLFNLLKTGHRMERPDNCSEEMYRLMLQ 986 Query: 250 CWQQDPAERPDFSEILEALKKI 315 CW+Q+P +RP F++I + L+K+ Sbjct: 987 CWKQEPDKRPVFADISKDLEKM 1008
>EPHA2_HUMAN (P29317) Ephrin type-A receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) Length = 976 Score = 60.8 bits (146), Expect = 4e-09 Identities = 29/87 (33%), Positives = 54/87 (62%), Gaps = 1/87 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I ++ + +DV+SFGI++WE++T G+ PY L+ + + + G R P + + + Sbjct: 789 ISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEV-MKAINDGFRLPTPMDCPSAIY 847 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKI 315 +L+ +CWQQ+ A RP F++I+ L K+ Sbjct: 848 QLMMQCWQQERARRPKFADIVSILDKL 874
>ERBB_AVIER (P00535) Tyrosine-protein kinase transforming protein erbB (EC| 2.7.10.1) Length = 604 Score = 60.5 bits (145), Expect = 5e-09 Identities = 31/90 (34%), Positives = 50/90 (55%), Gaps = 1/90 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I H+ Y H++DV+S+G+ +WEL+T G PY+ + P V++KG R P + Sbjct: 306 ILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGI-PASEISSVLEKGERLPQPPICTIDVY 364 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEE 324 ++ KCW D RP F E++ K+A + Sbjct: 365 MIMVKCWMIDADSRPKFRELIAEFSKMARD 394
>ERBB_ALV (P00534) Tyrosine-protein kinase transforming protein erbB (EC| 2.7.10.1) Length = 634 Score = 60.5 bits (145), Expect = 5e-09 Identities = 31/90 (34%), Positives = 50/90 (55%), Gaps = 1/90 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I H+ Y H++DV+S+G+ +WEL+T G PY+ + P V++KG R P + Sbjct: 306 ILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGI-PASEISSVLEKGERLPQPPICTIDVY 364 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEE 324 ++ KCW D RP F E++ K+A + Sbjct: 365 MIMVKCWMIDADSRPKFRELIAEFSKMARD 394
>EPA4A_BRARE (O13148) Ephrin type-A receptor 4a (EC 2.7.10.1) (Tyrosine-protein| kinase receptor ZEK2) (EPH-like kinase 2) (Fragment) Length = 292 Score = 60.1 bits (144), Expect = 6e-09 Identities = 29/87 (33%), Positives = 55/87 (63%), Gaps = 1/87 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I ++ + +DV+S+GI++WE+++ G+ PY ++ Q + +++G R P + L Sbjct: 179 ITYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSN-QDVIKAIEEGYRLPPPMDCPVSLH 237 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKI 315 +L+ CWQ++ AERP FS+I+ L K+ Sbjct: 238 QLMLDCWQKERAERPKFSQIVNMLDKL 264
>BTK_MOUSE (P35991) Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton's| tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB) Length = 658 Score = 60.1 bits (144), Expect = 6e-09 Identities = 29/91 (31%), Positives = 52/91 (57%), Gaps = 1/91 (1%) Frame = +1 Query: 55 VIEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKL 231 V+ + + K+D+++FG+L+WE+ + GK+PYE T + A + Q GLR P A ++ Sbjct: 567 VLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQ-GLRLYRPHLASERV 625 Query: 232 TELLQKCWQQDPAERPDFSEILEALKKIAEE 324 ++ CW + ERP F +L + + +E Sbjct: 626 YTIMYSCWHEKADERPSFKILLSNILDVMDE 656
>BMX_MOUSE (P97504) Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2)| (Bone marrow tyrosine kinase gene in chromosome X protein homolog) Length = 651 Score = 60.1 bits (144), Expect = 6e-09 Identities = 31/91 (34%), Positives = 53/91 (58%), Gaps = 1/91 (1%) Frame = +1 Query: 55 VIEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKL 231 V + Y K+DV++FGIL+WE+ + GK PY+ + V V Q G R P+ A + Sbjct: 559 VFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSEVVVKVSQ-GHRLYRPQLASDTI 617 Query: 232 TELLQKCWQQDPAERPDFSEILEALKKIAEE 324 +++ CW + P +RP F ++L A++ + E+ Sbjct: 618 YQIMYSCWHELPEKRPTFQQLLSAIEPLREQ 648
>EPHA7_RAT (P54759) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) Length = 998 Score = 60.1 bits (144), Expect = 6e-09 Identities = 29/87 (33%), Positives = 56/87 (64%), Gaps = 1/87 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I+++ + +DV+S+GI++WE+++ G+ PY ++ Q + +++G R P + A L Sbjct: 808 IQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSN-QDVIKAIEEGYRLPAPMDCPAGLH 866 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKI 315 +L+ CWQ++ AERP F +I+ L K+ Sbjct: 867 QLMLDCWQKERAERPKFEQIVGILDKM 893
>EPHA7_HUMAN (Q15375) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein-tyrosine kinase HEK11) Length = 998 Score = 60.1 bits (144), Expect = 6e-09 Identities = 29/87 (33%), Positives = 56/87 (64%), Gaps = 1/87 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I+++ + +DV+S+GI++WE+++ G+ PY ++ Q + +++G R P + A L Sbjct: 808 IQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSN-QDVIKAIEEGYRLPAPMDCPAGLH 866 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKI 315 +L+ CWQ++ AERP F +I+ L K+ Sbjct: 867 QLMLDCWQKERAERPKFEQIVGILDKM 893
>TIE1_MOUSE (Q06806) Tyrosine-protein kinase receptor Tie-1 precursor (EC| 2.7.10.1) Length = 1134 Score = 60.1 bits (144), Expect = 6e-09 Identities = 32/89 (35%), Positives = 54/89 (60%), Gaps = 1/89 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 + + Y K+DV+SFG+LLWE+++ G PY +T + + Q G R P+N ++ Sbjct: 1021 LNYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQ-GYRMEQPRNCDDEVY 1079 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAE 321 EL+++CW+ P ERP F++I L ++ E Sbjct: 1080 ELMRQCWRDRPYERPPFAQIALQLGRMLE 1108
>TIE1_HUMAN (P35590) Tyrosine-protein kinase receptor Tie-1 precursor (EC| 2.7.10.1) Length = 1138 Score = 60.1 bits (144), Expect = 6e-09 Identities = 32/89 (35%), Positives = 54/89 (60%), Gaps = 1/89 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 + + Y K+DV+SFG+LLWE+++ G PY +T + + Q G R P+N ++ Sbjct: 1025 LNYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQ-GYRMEQPRNCDDEVY 1083 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAE 321 EL+++CW+ P ERP F++I L ++ E Sbjct: 1084 ELMRQCWRDRPYERPPFAQIALQLGRMLE 1112
>SRC42_DROME (Q9V9J3) Tyrosine-protein kinase Src42A (EC 2.7.10.2) (Dsrc41)| Length = 517 Score = 59.7 bits (143), Expect = 8e-09 Identities = 31/78 (39%), Positives = 46/78 (58%), Gaps = 1/78 (1%) Frame = +1 Query: 64 HKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTEL 240 + + K+DV+SFGILL EL+T G+IPY +T + V + G R P N +L E+ Sbjct: 420 YSKFSIKSDVWSFGILLTELVTYGRIPYPGMTNAEVLTQV-EHGYRMPQPPNCEPRLYEI 478 Query: 241 LQKCWQQDPAERPDFSEI 294 + +CW +DP RP F + Sbjct: 479 MLECWHKDPMRRPTFETL 496
>EPHA3_RAT (O08680) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor REK4) (TYRO-4) Length = 984 Score = 59.7 bits (143), Expect = 8e-09 Identities = 30/90 (33%), Positives = 53/90 (58%), Gaps = 1/90 (1%) Frame = +1 Query: 64 HKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTEL 240 ++ + +DV+S+GI+LWE+++ G+ PY ++ Q + V +G R +P + A L +L Sbjct: 799 YRKFTSASDVWSYGIVLWEVMSYGERPYWEMSN-QDVIKAVDEGYRLPLPMDCPAALYQL 857 Query: 241 LQKCWQQDPAERPDFSEILEALKKIAEEVG 330 + CWQ+D RP F +I+ L K+ G Sbjct: 858 MLDCWQKDRNNRPKFEQIVSILDKLIRNPG 887
>EPHA5_CHICK (P54755) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK7) Length = 1013 Score = 59.7 bits (143), Expect = 8e-09 Identities = 31/87 (35%), Positives = 52/87 (59%), Gaps = 1/87 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I + + +DV+S+GI++WE+++ G+ PY +T Q + V++G R P + A L Sbjct: 826 IAFRKFTSASDVWSYGIVMWEVMSYGERPYWEMTN-QDVIKAVEEGYRLPSPMDCPAALY 884 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKI 315 +L+ CWQ+D RP F EI+ L K+ Sbjct: 885 QLMLDCWQKDRNSRPKFDEIVSMLDKL 911
>EGFR_HUMAN (P00533) Epidermal growth factor receptor precursor (EC 2.7.10.1)| (Receptor tyrosine-protein kinase ErbB-1) Length = 1210 Score = 59.3 bits (142), Expect = 1e-08 Identities = 30/90 (33%), Positives = 50/90 (55%), Gaps = 1/90 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I H+ Y H++DV+S+G+ +WEL+T G PY+ + P +++KG R P + Sbjct: 886 ILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGI-PASEISSILEKGERLPQPPICTIDVY 944 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEE 324 ++ KCW D RP F E++ K+A + Sbjct: 945 MIMVKCWMIDADSRPKFRELIIEFSKMARD 974
>RYK_MOUSE (Q01887) Tyrosine-protein kinase RYK precursor (EC 2.7.10.1)| (Kinase VIK) (NYK-R) (Met-related kinase) Length = 594 Score = 59.3 bits (142), Expect = 1e-08 Identities = 33/108 (30%), Positives = 56/108 (51%), Gaps = 1/108 (0%) Frame = +1 Query: 10 LGRREYDLTNFYLL*VIEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQ 186 LG E + L + + + +DV++FG+ LWEL+T G+ PY + P + A ++ Sbjct: 485 LGDNENRPVRWMALESLVNNEFSSASDVWAFGVTLWELMTLGQTPYVDIDPFEMAA-YLK 543 Query: 187 KGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFSEILEALKKIAEEVG 330 G R P N +L ++ CW DP ERP F ++++ L + +G Sbjct: 544 DGYRIAQPINCPDELFAVMACCWALDPEERPKFQQLVQCLTEFHAALG 591
>FGFR1_RAT (Q04589) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) Length = 822 Score = 59.3 bits (142), Expect = 1e-08 Identities = 29/82 (35%), Positives = 51/82 (62%), Gaps = 1/82 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y H++DV+SFG+LLWE+ T G P + P++ ++++G R P N +L +++ Sbjct: 677 YTHQSDVWSFGVLLWEIFTLGGSPNPGV-PVEELFKLLKEGHRMDKPSNCTNELYMMMRD 735 Query: 250 CWQQDPAERPDFSEILEALKKI 315 CW P++RP F +++E L +I Sbjct: 736 CWNAVPSQRPTFKQLVEDLDRI 757
>RYK_HUMAN (P34925) Tyrosine-protein kinase RYK precursor (EC 2.7.10.1)| Length = 604 Score = 59.3 bits (142), Expect = 1e-08 Identities = 33/108 (30%), Positives = 56/108 (51%), Gaps = 1/108 (0%) Frame = +1 Query: 10 LGRREYDLTNFYLL*VIEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQ 186 LG E + L + + + +DV++FG+ LWEL+T G+ PY + P + A ++ Sbjct: 495 LGDNENRPVRWMALESLVNNEFSSASDVWAFGVTLWELMTLGQTPYVDIDPFEMAA-YLK 553 Query: 187 KGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFSEILEALKKIAEEVG 330 G R P N +L ++ CW DP ERP F ++++ L + +G Sbjct: 554 DGYRIAQPINCPDELFAVMACCWALDPEERPKFQQLVQCLTEFHAALG 601
>INSRR_CAVPO (P14617) Insulin receptor-related protein precursor (EC 2.7.10.1)| (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] Length = 1300 Score = 59.3 bits (142), Expect = 1e-08 Identities = 30/77 (38%), Positives = 50/77 (64%), Gaps = 1/77 (1%) Frame = +1 Query: 85 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 261 +DV+SFG++LWE++T + PY+ L+ Q V+ G+ + H +L EL+ CWQQ Sbjct: 1173 SDVWSFGVVLWEIVTLAEQPYQGLSNEQVLKFVMDGGVLEELEDCPH-QLQELMSSCWQQ 1231 Query: 262 DPAERPDFSEILEALKK 312 +P RP F++IL +++K Sbjct: 1232 NPRLRPTFTQILNSIQK 1248
>FPS_AVISP (P00541) Tyrosine-protein kinase transforming protein Fps (EC| 2.7.10.2) Length = 533 Score = 59.3 bits (142), Expect = 1e-08 Identities = 30/79 (37%), Positives = 45/79 (56%), Gaps = 1/79 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y ++DV+SFGILLWE + G +PY L+ Q + Q G+R P+ + L+Q+ Sbjct: 448 YSSESDVWSFGILLWEAFSLGAVPYANLSNQQTREAIEQ-GVRLEPPEQCPEDVYRLMQR 506 Query: 250 CWQQDPAERPDFSEILEAL 306 CW+ DP RP F + + L Sbjct: 507 CWEYDPRRRPSFGAVHQDL 525
>EPHA5_MOUSE (Q60629) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7) Length = 877 Score = 59.3 bits (142), Expect = 1e-08 Identities = 31/87 (35%), Positives = 52/87 (59%), Gaps = 1/87 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I + + +DV+S+GI++WE+++ G+ PY +T Q + V++G R P + A L Sbjct: 689 IAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTN-QDVIKAVEEGYRLPSPMDCPAALY 747 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKI 315 +L+ CWQ+D RP F EI+ L K+ Sbjct: 748 QLMLDCWQKDRNSRPKFDEIVNMLDKL 774
>EGFR_MOUSE (Q01279) Epidermal growth factor receptor precursor (EC 2.7.10.1)| Length = 1210 Score = 58.9 bits (141), Expect = 1e-08 Identities = 30/90 (33%), Positives = 50/90 (55%), Gaps = 1/90 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I H+ Y H++DV+S+G+ +WEL+T G PY+ + P +++KG R P + Sbjct: 888 ILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGI-PASDISSILEKGERLPQPPICTIDVY 946 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEE 324 ++ KCW D RP F E++ K+A + Sbjct: 947 MIMVKCWMIDADSRPKFRELILEFSKMARD 976
>CSK_MOUSE (P41241) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| (Protein-tyrosine kinase MPK-2) (p50CSK) Length = 450 Score = 58.9 bits (141), Expect = 1e-08 Identities = 31/87 (35%), Positives = 51/87 (58%), Gaps = 1/87 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 + K + K+DV+SFGILLWE+ + G++PY + PL+ V V+KG + P + Sbjct: 358 LREKKFSTKSDVWSFGILLWEIYSFGRVPYPRI-PLKDVVPRVEKGYKMDAPDGCPPAVY 416 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKI 315 ++++ C D A RP F ++ E L+ I Sbjct: 417 DVMKNCSHLDAATRPTFLQLREQLEHI 443
>YES_AVISY (P00527) Tyrosine-protein kinase transforming protein YES (EC| 2.7.10.2) (Fragment) Length = 528 Score = 58.9 bits (141), Expect = 1e-08 Identities = 32/77 (41%), Positives = 48/77 (62%), Gaps = 1/77 (1%) Frame = +1 Query: 82 KADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQ 258 K+DV+SFGILL EL+T G++PY + + + V++G R P+ L EL++ CW+ Sbjct: 442 KSDVWSFGILLTELVTKGRVPYPGMVNREV-LEQVERGYRMPCPQGCPESLHELMKLCWK 500 Query: 259 QDPAERPDFSEILEALK 309 +DP ERP F I L+ Sbjct: 501 KDPDERPTFEYIQSFLE 517
>EPHA3_HUMAN (P29320) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4) Length = 983 Score = 58.9 bits (141), Expect = 1e-08 Identities = 31/92 (33%), Positives = 53/92 (57%), Gaps = 1/92 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I ++ + +DV+S+GI+LWE+++ G+ PY ++ Q + V +G R P + A L Sbjct: 796 IAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSN-QDVIKAVDEGYRLPPPMDCPAALY 854 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEEVG 330 +L+ CWQ+D RP F +I+ L K+ G Sbjct: 855 QLMLDCWQKDRNNRPKFEQIVSILDKLIRNPG 886
>ABL_FSVHY (P10447) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 439 Score = 58.9 bits (141), Expect = 1e-08 Identities = 29/80 (36%), Positives = 49/80 (61%), Gaps = 1/80 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 + + + K+DV++FG+LLWE+ T G PY + L +++K R P+ K+ Sbjct: 360 LAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGID-LSQVYELLEKDYRMERPEGCPEKVY 418 Query: 235 ELLQKCWQQDPAERPDFSEI 294 EL++ CWQ +P++RP F+EI Sbjct: 419 ELMRACWQWNPSDRPAFAEI 438
>YES_CHICK (P09324) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 540 Score = 58.9 bits (141), Expect = 1e-08 Identities = 32/77 (41%), Positives = 48/77 (62%), Gaps = 1/77 (1%) Frame = +1 Query: 82 KADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQ 258 K+DV+SFGILL EL+T G++PY + + + V++G R P+ L EL++ CW+ Sbjct: 449 KSDVWSFGILLTELVTKGRVPYPGMVNREV-LEQVERGYRMPCPQGCPESLHELMKLCWK 507 Query: 259 QDPAERPDFSEILEALK 309 +DP ERP F I L+ Sbjct: 508 KDPDERPTFEYIQSFLE 524
>XMRK_XIPMA (P13388) Melanoma receptor tyrosine-protein kinase precursor (EC| 2.7.10.1) Length = 1167 Score = 58.9 bits (141), Expect = 1e-08 Identities = 28/85 (32%), Positives = 50/85 (58%), Gaps = 1/85 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y H++DV+S+G+ +WEL+T G PY+ + P + V++ G R P ++ ++ K Sbjct: 889 YTHQSDVWSYGVTVWELMTFGSKPYDGI-PAKEIASVLENGERLPQPPICTIEVYMIILK 947 Query: 250 CWQQDPAERPDFSEILEALKKIAEE 324 CW DP+ RP F E++ ++A + Sbjct: 948 CWMIDPSSRPRFRELVGEFSQMARD 972
>FPS_FUJSV (P00530) Tyrosine-protein kinase transforming protein FPS (EC| 2.7.10.2) Length = 873 Score = 58.9 bits (141), Expect = 1e-08 Identities = 30/79 (37%), Positives = 45/79 (56%), Gaps = 1/79 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y ++DV+SFGILLWE + G +PY L+ Q + Q G+R P+ + L+Q+ Sbjct: 788 YSSESDVWSFGILLWEAFSLGAVPYANLSNQQTREAIEQ-GVRLEPPEQCPEDVYRLMQR 846 Query: 250 CWQQDPAERPDFSEILEAL 306 CW+ DP RP F + + L Sbjct: 847 CWEYDPHRRPSFGAVHQDL 865
>IGF1R_HUMAN (P08069) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 recepto Length = 1367 Score = 58.5 bits (140), Expect = 2e-08 Identities = 32/80 (40%), Positives = 49/80 (61%), Gaps = 1/80 (1%) Frame = +1 Query: 85 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 261 +DV+SFG++LWE+ T + PY+ L+ Q V++ GL P N L EL++ CWQ Sbjct: 1193 SDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDK-PDNCPDMLFELMRMCWQY 1251 Query: 262 DPAERPDFSEILEALKKIAE 321 +P RP F EI+ ++K+ E Sbjct: 1252 NPKMRPSFLEIISSIKEEME 1271
>EPHA2_MOUSE (Q03145) Ephrin type-A receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2) Length = 977 Score = 58.5 bits (140), Expect = 2e-08 Identities = 27/87 (31%), Positives = 54/87 (62%), Gaps = 1/87 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I ++ + +DV+S+GI++WE++T G+ PY L+ + + + G R P + + + Sbjct: 790 ISYRKFTSASDVWSYGIVMWEVMTYGERPYWELSNHEV-MKAINDGFRLPTPMDCPSAIY 848 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKI 315 +L+ +CWQQ+ + RP F++I+ L K+ Sbjct: 849 QLMMQCWQQERSRRPKFADIVSILDKL 875
>BMX_HUMAN (P51813) Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2)| (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38) Length = 675 Score = 58.5 bits (140), Expect = 2e-08 Identities = 32/96 (33%), Positives = 55/96 (57%), Gaps = 1/96 (1%) Frame = +1 Query: 55 VIEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKL 231 V + Y K+DV++FGIL+WE+ + GK PY+ Q + V Q G R P A + Sbjct: 583 VFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSQVVLKVSQ-GHRLYRPHLASDTI 641 Query: 232 TELLQKCWQQDPAERPDFSEILEALKKIAEEVGDEH 339 +++ CW + P +RP F ++L +++ + E+ D+H Sbjct: 642 YQIMYSCWHELPEKRPTFQQLLSSIEPLREK--DKH 675
>FES_MOUSE (P16879) Proto-oncogene tyrosine-protein kinase Fes/Fps (EC| 2.7.10.2) (C-Fes) Length = 820 Score = 58.5 bits (140), Expect = 2e-08 Identities = 33/82 (40%), Positives = 46/82 (56%), Gaps = 1/82 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y ++DV+SFGILLWE + G PY LT Q V+KG R P+ + L+++ Sbjct: 735 YSSESDVWSFGILLWETFSLGASPYPNLTNQQTRE-FVEKGHRLPCPELCPDAVFRLMEQ 793 Query: 250 CWQQDPAERPDFSEILEALKKI 315 CW +P +RP FS I + L I Sbjct: 794 CWAYEPGQRPSFSIICQELHSI 815
>EPHA7_CHICK (O42422) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEPHA7) (Tyrosine-protein kinase receptor CEK11) Length = 993 Score = 58.5 bits (140), Expect = 2e-08 Identities = 28/87 (32%), Positives = 55/87 (63%), Gaps = 1/87 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I+++ + +DV+S+GI++WE+++ G+ PY ++ Q + +++G R P + A L Sbjct: 803 IQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSN-QDVIKAIEEGYRLPAPMDCPAGLH 861 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKI 315 +L+ CWQ++ ERP F +I+ L K+ Sbjct: 862 QLMLDCWQKERGERPKFEQIVGILDKM 888
>VGFR3_MOUSE (P35917) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1363 Score = 58.5 bits (140), Expect = 2e-08 Identities = 30/97 (30%), Positives = 53/97 (54%), Gaps = 1/97 (1%) Frame = +1 Query: 67 KPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELL 243 K Y ++DV+SFG+LLWE+ + G PY + + ++ G R P+ A + ++ Sbjct: 1089 KVYTTQSDVWSFGVLLWEIFSLGASPYPGVQINEEFCQRLKDGTRMRAPELATPAIRHIM 1148 Query: 244 QKCWQQDPAERPDFSEILEALKKIAEEVGDEHDGKHK 354 Q CW DP RP FS+++E L + + G + + + + Sbjct: 1149 QSCWSGDPKARPAFSDLVEILGDLLQGGGWQEEEEER 1185
>VGFR2_BRARE (Q8AXB3) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Receptor tyrosine kinase flk-1) Length = 1302 Score = 58.5 bits (140), Expect = 2e-08 Identities = 29/96 (30%), Positives = 57/96 (59%), Gaps = 1/96 (1%) Frame = +1 Query: 67 KPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELL 243 K Y ++DV+SFG+L+WE+ + G PY L + +++G R P+ + +++ + + Sbjct: 1055 KIYTTQSDVWSFGVLMWEIFSLGASPYPGLHIDEEFCCRLKEGTRMKAPEYSSSEIYQTM 1114 Query: 244 QKCWQQDPAERPDFSEILEALKKIAEEVGDEHDGKH 351 CW +P++RP F+E++E L + + + +GKH Sbjct: 1115 LDCWHGEPSQRPTFTELVERLGDLL-QASVQQEGKH 1149
>EPHA5_RAT (P54757) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) Length = 1005 Score = 58.2 bits (139), Expect = 2e-08 Identities = 30/87 (34%), Positives = 52/87 (59%), Gaps = 1/87 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I + + +DV+S+GI++WE+++ G+ PY +T Q + V++G R P + A L Sbjct: 852 IAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTN-QDVIKAVEEGYRLPSPMDCPAALY 910 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKI 315 +L+ CWQ+D RP F +I+ L K+ Sbjct: 911 QLMLDCWQKDRNSRPKFDDIVNMLDKL 937
>FES_HUMAN (P07332) Proto-oncogene tyrosine-protein kinase Fes/Fps (EC| 2.7.10.2) (C-Fes) Length = 822 Score = 58.2 bits (139), Expect = 2e-08 Identities = 32/82 (39%), Positives = 47/82 (57%), Gaps = 1/82 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y ++DV+SFGILLWE + G PY L+ Q V+KG R P+ + L+++ Sbjct: 737 YSSESDVWSFGILLWETFSLGASPYPNLSNQQTRE-FVEKGGRLPCPELCPDAVFRLMEQ 795 Query: 250 CWQQDPAERPDFSEILEALKKI 315 CW +P +RP FS I + L+ I Sbjct: 796 CWAYEPGQRPSFSTIYQELQSI 817
>EPHA8_RAT (P29321) Ephrin type-A receptor 8 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor EEK) (EPH- and ELK-related kinase) (Fragment) Length = 372 Score = 58.2 bits (139), Expect = 2e-08 Identities = 29/87 (33%), Positives = 50/87 (57%), Gaps = 1/87 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I + + +DV+SFG+++WE+L G+ PY +T Q + V++G R P L Sbjct: 177 IAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTN-QDVISSVEEGYRLPAPMGCPRALH 235 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKI 315 +L+ CW +D A+RP FS ++ L+ + Sbjct: 236 QLMLDCWHKDRAQRPRFSHVVSVLEAL 262
>FES_FSVGA (P00542) Tyrosine-protein kinase transforming protein Fes (EC| 2.7.10.2) Length = 609 Score = 58.2 bits (139), Expect = 2e-08 Identities = 32/82 (39%), Positives = 47/82 (57%), Gaps = 1/82 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y ++DV+SFGILLWE + G PY L+ Q V+KG R P+ + L+++ Sbjct: 524 YSSESDVWSFGILLWETFSLGASPYPNLSNQQTRE-FVEKGGRLPCPELCPDAVFRLMEQ 582 Query: 250 CWQQDPAERPDFSEILEALKKI 315 CW +P +RP FS I + L+ I Sbjct: 583 CWAYEPGQRPSFSAIYQELQSI 604
>SEA_AVIET (P23049) Tyrosine-protein kinase transforming protein SEA (EC| 2.7.10.2) Length = 370 Score = 58.2 bits (139), Expect = 2e-08 Identities = 32/95 (33%), Positives = 52/95 (54%), Gaps = 1/95 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 ++ + + K+DV+SFG+L+WELLT G PY + P A + +G R P+ L Sbjct: 237 LQTQKFTTKSDVWSFGVLMWELLTRGASPYPEVDPYDMA-RYLLRGRRLPQPQPCPDTLY 295 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEEVGDEH 339 ++ CW P ERP FS ++ L+++ + EH Sbjct: 296 GVMLSCWAPTPEERPSFSGLVCELERVLASLEGEH 330
>FES_FELCA (P14238) Proto-oncogene tyrosine-protein kinase FES/FPS (EC| 2.7.10.2) (C-FES) Length = 820 Score = 58.2 bits (139), Expect = 2e-08 Identities = 32/82 (39%), Positives = 47/82 (57%), Gaps = 1/82 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y ++DV+SFGILLWE + G PY L+ Q V+KG R P+ + L+++ Sbjct: 735 YSSESDVWSFGILLWETFSLGASPYPNLSNQQTRE-FVEKGGRLPCPELCPDAVFRLMEQ 793 Query: 250 CWQQDPAERPDFSEILEALKKI 315 CW +P +RP FS I + L+ I Sbjct: 794 CWAYEPGQRPSFSAIYQELQSI 815
>VGFR3_RAT (Q91ZT1) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1363 Score = 58.2 bits (139), Expect = 2e-08 Identities = 30/89 (33%), Positives = 49/89 (55%), Gaps = 1/89 (1%) Frame = +1 Query: 67 KPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELL 243 K Y ++DV+SFG+LLWE+ + G PY + + ++ G R P+ A + ++ Sbjct: 1089 KVYTTQSDVWSFGVLLWEIFSLGASPYPGVQINEEFCQRLKDGTRMRAPELATPAIRHIM 1148 Query: 244 QKCWQQDPAERPDFSEILEALKKIAEEVG 330 Q CW DP RP FS+++E L + + G Sbjct: 1149 QSCWSGDPKARPAFSDLVEILGDLLQGGG 1177
>FYN_XENLA (P13406) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 536 Score = 58.2 bits (139), Expect = 2e-08 Identities = 30/69 (43%), Positives = 45/69 (65%), Gaps = 1/69 (1%) Frame = +1 Query: 82 KADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQ 258 K+DV+SFGILL EL+T G++PY + + + V++G R P++ L EL+ CW+ Sbjct: 445 KSDVWSFGILLTELVTKGRVPYPGMNNREV-LEQVERGYRMPCPQDCPISLHELMLNCWK 503 Query: 259 QDPAERPDF 285 +DP ERP F Sbjct: 504 KDPEERPTF 512
>M3K7_DROME (Q9V3Q6) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (TGF-beta-activated kinase 1) (dTAK1) Length = 678 Score = 57.8 bits (138), Expect = 3e-08 Identities = 26/90 (28%), Positives = 47/90 (52%) Frame = +1 Query: 55 VIEHKPYDHKADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 V E Y K D+FS+ I+LWE+L+ K P++ + + KG RP + ++ Sbjct: 184 VFEGSKYTEKCDIFSWAIVLWEVLSRKQPFKGIDNAYTIQWKIYKGERPPLLTTCPKRIE 243 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEE 324 +L+ CW+ P +RP I+ + +I ++ Sbjct: 244 DLMTACWKTVPEDRPSMQYIVGVMHEIVKD 273
>ANKK1_HUMAN (Q8NFD2) Ankyrin repeat and protein kinase domain-containing| protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288) Length = 765 Score = 57.8 bits (138), Expect = 3e-08 Identities = 30/78 (38%), Positives = 46/78 (58%), Gaps = 7/78 (8%) Frame = +1 Query: 82 KADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTI-------PKNAHAKLTEL 240 K DV+SF I++WELLT K PY + + V G+RP++ P A ++ +L Sbjct: 206 KYDVYSFAIVIWELLTQKKPYSGFNMMMIIIRVA-AGMRPSLQPVSDQWPSEAQ-QMVDL 263 Query: 241 LQKCWQQDPAERPDFSEI 294 +++CW QDP +RP F +I Sbjct: 264 MKRCWDQDPKKRPCFLDI 281
>INSR_AEDAE (Q93105) Insulin-like receptor precursor (EC 2.7.10.1) (MIR)| [Contains: Insulin-like receptor alpha chain; Insulin-like receptor beta chain] Length = 1390 Score = 57.8 bits (138), Expect = 3e-08 Identities = 30/79 (37%), Positives = 44/79 (55%), Gaps = 1/79 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 + +DVFS+G++LWE+ T PY+ LT Q V+ G+ P+N L L+++ Sbjct: 1216 FSSSSDVFSYGVVLWEMATLASQPYQGLTNDQVLRYVIDGGVMER-PENCPDNLYNLMRR 1274 Query: 250 CWQQDPAERPDFSEILEAL 306 CWQ P RP F EI+ L Sbjct: 1275 CWQHRPTARPTFMEIISEL 1293
>ALK_MOUSE (P97793) ALK tyrosine kinase receptor precursor (EC 2.7.10.1)| (Anaplastic lymphoma kinase) (CD246 antigen) Length = 1621 Score = 57.8 bits (138), Expect = 3e-08 Identities = 29/85 (34%), Positives = 48/85 (56%), Gaps = 1/85 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 + K D +SFG+LLWE+ + G +PY + Q + V G R PKN + ++ + Sbjct: 1310 FTSKTDTWSFGVLLWEIFSLGYMPYPSKSN-QEVLEFVTSGGRMDPPKNCPGPVYRIMTQ 1368 Query: 250 CWQQDPAERPDFSEILEALKKIAEE 324 CWQ P +RP+F+ ILE ++ ++ Sbjct: 1369 CWQHQPEDRPNFAIILERIEYCTQD 1393
>VGFR2_MOUSE (P35918) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) (Kinase NYK) Length = 1367 Score = 57.8 bits (138), Expect = 3e-08 Identities = 30/93 (32%), Positives = 52/93 (55%), Gaps = 1/93 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y ++DV+SFG+LLWE+ + G PY + + +++G R P ++ + + Sbjct: 1080 YTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLD 1139 Query: 250 CWQQDPAERPDFSEILEALKKIAEEVGDEHDGK 348 CW +DP +RP FSE++E L + + + DGK Sbjct: 1140 CWHEDPNQRPSFSELVEHLGNLL-QANAQQDGK 1171
>TIE1_BOVIN (Q06805) Tyrosine-protein kinase receptor Tie-1 precursor (EC| 2.7.10.1) Length = 1136 Score = 57.8 bits (138), Expect = 3e-08 Identities = 31/89 (34%), Positives = 53/89 (59%), Gaps = 1/89 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 + + Y K+DV+SFG+LLWE+++ G PY +T + + Q R P+N ++ Sbjct: 1023 LNYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQ-AYRMEQPRNCDDEVY 1081 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAE 321 EL+++CW+ P ERP F++I L ++ E Sbjct: 1082 ELMRQCWRDRPYERPPFAQIALQLGRMLE 1110
>KIT_CHICK (Q08156) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 960 Score = 57.8 bits (138), Expect = 3e-08 Identities = 25/81 (30%), Positives = 50/81 (61%), Gaps = 1/81 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y ++DV+S+GILLWEL + G PY + ++++G R P+ + ++ ++++ Sbjct: 831 YTFESDVWSYGILLWELFSLGSSPYPGMPVDSKFYKMIKEGYRMFSPECSPPEMYDIMKS 890 Query: 250 CWQQDPAERPDFSEILEALKK 312 CW DP +RP F +I++ +++ Sbjct: 891 CWDADPLQRPTFKQIVQLIEQ 911
>ALK_HUMAN (Q9UM73) ALK tyrosine kinase receptor precursor (EC 2.7.10.1)| (Anaplastic lymphoma kinase) (CD246 antigen) Length = 1620 Score = 57.8 bits (138), Expect = 3e-08 Identities = 29/85 (34%), Positives = 48/85 (56%), Gaps = 1/85 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 + K D +SFG+LLWE+ + G +PY + Q + V G R PKN + ++ + Sbjct: 1306 FTSKTDTWSFGVLLWEIFSLGYMPYPSKSN-QEVLEFVTSGGRMDPPKNCPGPVYRIMTQ 1364 Query: 250 CWQQDPAERPDFSEILEALKKIAEE 324 CWQ P +RP+F+ ILE ++ ++ Sbjct: 1365 CWQHQPEDRPNFAIILERIEYCTQD 1389
>ABL_DROME (P00522) Tyrosine-protein kinase Abl (EC 2.7.10.2) (Abelson| protein) (D-ash) Length = 1620 Score = 57.8 bits (138), Expect = 3e-08 Identities = 30/90 (33%), Positives = 50/90 (55%), Gaps = 1/90 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 + + + K+DV++FG+LLWE+ T G PY + L + KG R P ++ Sbjct: 540 LAYNKFSTKSDVWAFGVLLWEIATYGMSPYPAID-LTDVYHKLDKGYRMERPPGCPPEVY 598 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEE 324 +L+++CWQ D +RP F I AL+ + +E Sbjct: 599 DLMRQCWQWDATDRPTFKSIHHALEHMFQE 628
>FYN_HUMAN (P06241) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) (Protooncogene Syn) (SLK) Length = 536 Score = 57.8 bits (138), Expect = 3e-08 Identities = 31/77 (40%), Positives = 48/77 (62%), Gaps = 1/77 (1%) Frame = +1 Query: 82 KADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQ 258 K+DV+SFGILL EL+T G++PY + + + V++G R P++ L EL+ CW+ Sbjct: 445 KSDVWSFGILLTELVTKGRVPYPGMNNREV-LEQVERGYRMPCPQDCPISLHELMIHCWK 503 Query: 259 QDPAERPDFSEILEALK 309 +DP ERP F + L+ Sbjct: 504 KDPEERPTFEYLQSFLE 520
>EPHA5_HUMAN (P54756) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein-tyrosine kinase HEK7) Length = 1037 Score = 57.8 bits (138), Expect = 3e-08 Identities = 30/87 (34%), Positives = 52/87 (59%), Gaps = 1/87 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I + + +DV+S+GI++WE+++ G+ PY +T Q + V++G R P + A L Sbjct: 850 IAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTN-QDVIKAVEEGYRLPSPMDCPAALY 908 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKI 315 +L+ CWQ++ RP F EI+ L K+ Sbjct: 909 QLMLDCWQKERNSRPKFDEIVNMLDKL 935
>LTK_MOUSE (P08923) Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1)| Length = 888 Score = 57.4 bits (137), Expect = 4e-08 Identities = 29/85 (34%), Positives = 46/85 (54%), Gaps = 1/85 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 + K D +SFG+LLWE+ + G +PY T Q + + G R P+N + ++ + Sbjct: 696 FTSKTDSWSFGVLLWEIFSLGYMPYPGHTN-QEVLDFIATGNRMDPPRNCPGPVYRIMTQ 754 Query: 250 CWQQDPAERPDFSEILEALKKIAEE 324 CWQ P RPDF ILE ++ ++ Sbjct: 755 CWQHQPELRPDFGSILERIQYCTQD 779
>FAK1_XENLA (Q91738) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| Length = 1068 Score = 57.4 bits (137), Expect = 4e-08 Identities = 30/90 (33%), Positives = 48/90 (53%), Gaps = 1/90 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I + + +DV+ FG+ +WE+L G P++ + +G ++ G R +P N L Sbjct: 607 INFRRFTSASDVWMFGVCMWEILMYGVKPFQGVKN-NDVIGRIENGERLPMPPNCPPTLY 665 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEE 324 L+ KCW DP+ RP F+E+ L I EE Sbjct: 666 SLMTKCWAYDPSRRPRFTELKAQLSTILEE 695
>FAK1_CHICK (Q00944) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| Length = 1053 Score = 57.4 bits (137), Expect = 4e-08 Identities = 30/90 (33%), Positives = 48/90 (53%), Gaps = 1/90 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I + + +DV+ FG+ +WE+L G P++ + +G ++ G R +P N L Sbjct: 594 INFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKN-NDVIGRIENGERLPMPPNCPPTLY 652 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEE 324 L+ KCW DP+ RP F+E+ L I EE Sbjct: 653 SLMTKCWAYDPSRRPRFTELKAQLSTILEE 682
>BRAF1_COTJA (P34908) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (RMIL serine/threonine-protein kinase) (c-RMIL) Length = 807 Score = 57.4 bits (137), Expect = 4e-08 Identities = 30/97 (30%), Positives = 56/97 (57%), Gaps = 4/97 (4%) Frame = +1 Query: 61 EHKPYDHKADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKG-LRPTIPK---NAHAK 228 + PY ++DV++FGI+L+EL+TG++PY + + +V +G L P + K N Sbjct: 669 DKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKA 728 Query: 229 LTELLQKCWQQDPAERPDFSEILEALKKIAEEVGDEH 339 + L+ +C ++ ERP F +IL +++ +A + H Sbjct: 729 MKRLMAECLKKKRDERPLFPQILASIELLARSLPKIH 765
>RMIL_AVEVR (P27966) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 450 Score = 57.4 bits (137), Expect = 4e-08 Identities = 30/97 (30%), Positives = 56/97 (57%), Gaps = 4/97 (4%) Frame = +1 Query: 61 EHKPYDHKADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKG-LRPTIPK---NAHAK 228 + PY ++DV++FGI+L+EL+TG++PY + + +V +G L P + K N Sbjct: 255 DKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKA 314 Query: 229 LTELLQKCWQQDPAERPDFSEILEALKKIAEEVGDEH 339 + L+ +C ++ ERP F +IL +++ +A + H Sbjct: 315 MKRLMAECLKKKRDERPLFPQILASIELLARSLPKIH 351
>LCK_HUMAN (P06239) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell-specific protein-tyrosine kinase) Length = 508 Score = 57.4 bits (137), Expect = 4e-08 Identities = 32/100 (32%), Positives = 60/100 (60%), Gaps = 1/100 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I + + K+DV+SFGILL E++T G+IPY +T + + +++G R P N +L Sbjct: 411 INYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEV-IQNLERGYRMVRPDNCPEELY 469 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEEVGDEHDGKHK 354 +L++ CW++ P +RP F + L+ + E+ +G+++ Sbjct: 470 QLMRLCWKERPEDRPTF----DYLRSVLEDFFTATEGQYQ 505
>FAK1_RAT (O35346) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| Length = 1055 Score = 57.4 bits (137), Expect = 4e-08 Identities = 30/90 (33%), Positives = 48/90 (53%), Gaps = 1/90 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I + + +DV+ FG+ +WE+L G P++ + +G ++ G R +P N L Sbjct: 594 INFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKN-NDVIGRIENGERLPMPPNCPPTLY 652 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEE 324 L+ KCW DP+ RP F+E+ L I EE Sbjct: 653 SLMTKCWAYDPSRRPRFTELKAQLSTILEE 682
>FAK1_MOUSE (P34152) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| Length = 1090 Score = 57.4 bits (137), Expect = 4e-08 Identities = 30/90 (33%), Positives = 48/90 (53%), Gaps = 1/90 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I + + +DV+ FG+ +WE+L G P++ + +G ++ G R +P N L Sbjct: 632 INFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKN-NDVIGRIENGERLPMPPNCPPTLY 690 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEE 324 L+ KCW DP+ RP F+E+ L I EE Sbjct: 691 SLMTKCWAYDPSRRPRFTELKAQLSTILEE 720
>RMIL_AVII1 (P10533) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 367 Score = 57.4 bits (137), Expect = 4e-08 Identities = 30/97 (30%), Positives = 56/97 (57%), Gaps = 4/97 (4%) Frame = +1 Query: 61 EHKPYDHKADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKG-LRPTIPK---NAHAK 228 + PY ++DV++FGI+L+EL+TG++PY + + +V +G L P + K N Sbjct: 239 DKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKA 298 Query: 229 LTELLQKCWQQDPAERPDFSEILEALKKIAEEVGDEH 339 + L+ +C ++ ERP F +IL +++ +A + H Sbjct: 299 MKRLMAECLKKKRDERPLFPQILASIELLARSLPKIH 335
>FAK1_HUMAN (Q05397) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| (Protein-tyrosine kinase 2) Length = 1052 Score = 57.4 bits (137), Expect = 4e-08 Identities = 30/90 (33%), Positives = 48/90 (53%), Gaps = 1/90 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I + + +DV+ FG+ +WE+L G P++ + +G ++ G R +P N L Sbjct: 594 INFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKN-NDVIGRIENGERLPMPPNCPPTLY 652 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEE 324 L+ KCW DP+ RP F+E+ L I EE Sbjct: 653 SLMTKCWAYDPSRRPRFTELKAQLSTILEE 682
>IGF1R_BOVIN (Q05688) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] (F Length = 640 Score = 57.4 bits (137), Expect = 4e-08 Identities = 31/76 (40%), Positives = 47/76 (61%), Gaps = 1/76 (1%) Frame = +1 Query: 85 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 261 +DV+SFG++LWE+ T + PY+ L+ Q V++ GL P N L EL++ CWQ Sbjct: 466 SDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDK-PDNCPDMLFELMRMCWQY 524 Query: 262 DPAERPDFSEILEALK 309 +P RP F EI+ ++K Sbjct: 525 NPKMRPSFLEIISSVK 540
>BRAF1_HUMAN (P15056) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1) Length = 766 Score = 57.4 bits (137), Expect = 4e-08 Identities = 30/97 (30%), Positives = 56/97 (57%), Gaps = 4/97 (4%) Frame = +1 Query: 61 EHKPYDHKADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKG-LRPTIPK---NAHAK 228 + PY ++DV++FGI+L+EL+TG++PY + + +V +G L P + K N Sbjct: 629 DKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKA 688 Query: 229 LTELLQKCWQQDPAERPDFSEILEALKKIAEEVGDEH 339 + L+ +C ++ ERP F +IL +++ +A + H Sbjct: 689 MKRLMAECLKKKRDERPLFPQILASIELLARSLPKIH 725
>RYK2_DROME (Q9V422) Tyrosine-protein kinase Dnt precursor (EC 2.7.10.1)| (Protein doughnut) Length = 584 Score = 57.4 bits (137), Expect = 4e-08 Identities = 32/107 (29%), Positives = 54/107 (50%), Gaps = 1/107 (0%) Frame = +1 Query: 10 LGRREYDLTNFYLL*VIEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQ 186 LG E + L ++HK + +D ++FG+L+WEL T K PY + P + ++ Sbjct: 475 LGDSENRPVKWMSLEALQHKQFSEASDSWAFGVLMWELCTSAKQPYAEVDPFEME-HYLK 533 Query: 187 KGLRPTIPKNAHAKLTELLQKCWQQDPAERPDFSEILEALKKIAEEV 327 G R P N +L ++ CW PAERP F+++ L + ++ Sbjct: 534 DGYRLAQPFNCPDELFTIMAYCWALLPAERPTFAQLQSCLSEFYSQI 580
>FYN_MOUSE (P39688) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 57.4 bits (137), Expect = 4e-08 Identities = 30/69 (43%), Positives = 45/69 (65%), Gaps = 1/69 (1%) Frame = +1 Query: 82 KADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQ 258 K+DV+SFGILL EL+T G++PY + + + V++G R P++ L EL+ CW+ Sbjct: 442 KSDVWSFGILLTELVTKGRVPYPGMNNREV-LEQVERGYRMPCPQDCPISLHELMIHCWK 500 Query: 259 QDPAERPDF 285 +DP ERP F Sbjct: 501 KDPEERPTF 509
>FYN_CHICK (Q05876) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 57.4 bits (137), Expect = 4e-08 Identities = 30/69 (43%), Positives = 45/69 (65%), Gaps = 1/69 (1%) Frame = +1 Query: 82 KADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQ 258 K+DV+SFGILL EL+T G++PY + + + V++G R P++ L EL+ CW+ Sbjct: 442 KSDVWSFGILLTELVTKGRVPYPGMNNREV-LEQVERGYRMPCPQDCPISLHELMIHCWK 500 Query: 259 QDPAERPDF 285 +DP ERP F Sbjct: 501 KDPEERPTF 509
>BRAF1_MOUSE (P28028) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Fragment) Length = 328 Score = 57.4 bits (137), Expect = 4e-08 Identities = 30/97 (30%), Positives = 56/97 (57%), Gaps = 4/97 (4%) Frame = +1 Query: 61 EHKPYDHKADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKG-LRPTIPK---NAHAK 228 + PY ++DV++FGI+L+EL+TG++PY + + +V +G L P + K N Sbjct: 191 DKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKA 250 Query: 229 LTELLQKCWQQDPAERPDFSEILEALKKIAEEVGDEH 339 + L+ +C ++ ERP F +IL +++ +A + H Sbjct: 251 MKRLMAECLKKKRDERPLFPQILASIELLARSLPKIH 287
>BRAF1_CHICK (Q04982) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Rmil serine/threonine-protein kinase) (c-Rmil) Length = 806 Score = 57.4 bits (137), Expect = 4e-08 Identities = 30/97 (30%), Positives = 56/97 (57%), Gaps = 4/97 (4%) Frame = +1 Query: 61 EHKPYDHKADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKG-LRPTIPK---NAHAK 228 + PY ++DV++FGI+L+EL+TG++PY + + +V +G L P + K N Sbjct: 669 DKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKA 728 Query: 229 LTELLQKCWQQDPAERPDFSEILEALKKIAEEVGDEH 339 + L+ +C ++ ERP F +IL +++ +A + H Sbjct: 729 MKRLMAECLKKKRDERPLFPQILASIELLARSLPKIH 765
>ANPRB_HUMAN (P20594) Atrial natriuretic peptide receptor B precursor (ANP-B)| (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor) Length = 1047 Score = 57.4 bits (137), Expect = 4e-08 Identities = 37/92 (40%), Positives = 52/92 (56%), Gaps = 9/92 (9%) Frame = +1 Query: 82 KADVFSFGILLWELLTGKIPYEYLTPLQAA----VGVVQKGLRPTI-PKNAHAKLTE--- 237 KADV+SFGI+L E+ P+ YL L + V V+ G RP P +L E Sbjct: 704 KADVYSFGIILQEIALRSGPF-YLEGLDLSPKEIVQKVRNGQRPYFRPSIDRTQLNEELV 762 Query: 238 -LLQKCWQQDPAERPDFSEILEALKKIAEEVG 330 L+++CW QDPAERPDF +I +++ +E G Sbjct: 763 LLMERCWAQDPAERPDFGQIKGFIRRFNKEGG 794
>ANPRB_BOVIN (P46197) Atrial natriuretic peptide receptor B precursor (ANP-B)| (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor) Length = 1047 Score = 57.4 bits (137), Expect = 4e-08 Identities = 37/92 (40%), Positives = 52/92 (56%), Gaps = 9/92 (9%) Frame = +1 Query: 82 KADVFSFGILLWELLTGKIPYEYLTPLQAA----VGVVQKGLRPTI-PKNAHAKLTE--- 237 KADV+SFGI+L E+ P+ YL L + V V+ G RP P +L E Sbjct: 704 KADVYSFGIILQEIALRSGPF-YLEGLDLSPKEIVQKVRNGQRPYFRPSIDRTQLNEELV 762 Query: 238 -LLQKCWQQDPAERPDFSEILEALKKIAEEVG 330 L+++CW QDPAERPDF +I +++ +E G Sbjct: 763 LLMERCWAQDPAERPDFGQIKGFIRRFNKEGG 794
>MET_MOUSE (P16056) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1379 Score = 57.0 bits (136), Expect = 5e-08 Identities = 32/95 (33%), Positives = 50/95 (52%), Gaps = 1/95 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 ++ + + K+DV+SFG+LLWEL+T G PY + + ++Q G R P+ L Sbjct: 1253 LQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITIYLLQ-GRRLLQPEYCPDALY 1311 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEEVGDEH 339 E++ KCW RP FSE++ + I EH Sbjct: 1312 EVMLKCWHPKAEMRPSFSELVSRISSIFSTFIGEH 1346
>MET_CALMO (Q2QLC0) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 57.0 bits (136), Expect = 5e-08 Identities = 33/95 (34%), Positives = 50/95 (52%), Gaps = 1/95 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 ++ + + K+DV+SFG+LLWEL+T G PY + V ++Q G R P+ L Sbjct: 1255 LQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQ-GRRLLQPEYCPDPLY 1313 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEEVGDEH 339 E++ KCW RP FSE++ + I EH Sbjct: 1314 EVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEH 1348
>MET_CALJA (Q2QLG5) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 57.0 bits (136), Expect = 5e-08 Identities = 33/95 (34%), Positives = 50/95 (52%), Gaps = 1/95 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 ++ + + K+DV+SFG+LLWEL+T G PY + V ++Q G R P+ L Sbjct: 1255 LQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQ-GRRLLQPEYCPDPLY 1313 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEEVGDEH 339 E++ KCW RP FSE++ + I EH Sbjct: 1314 EVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEH 1348
>MET_PONPY (Q2IBD8) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 57.0 bits (136), Expect = 5e-08 Identities = 33/95 (34%), Positives = 50/95 (52%), Gaps = 1/95 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 ++ + + K+DV+SFG+LLWEL+T G PY + V ++Q G R P+ L Sbjct: 1255 LQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQ-GRRLLQPEYCPDPLY 1313 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEEVGDEH 339 E++ KCW RP FSE++ + I EH Sbjct: 1314 EVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEH 1348
>MET_PANTR (Q2QLF1) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 57.0 bits (136), Expect = 5e-08 Identities = 33/95 (34%), Positives = 50/95 (52%), Gaps = 1/95 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 ++ + + K+DV+SFG+LLWEL+T G PY + V ++Q G R P+ L Sbjct: 1255 LQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQ-GRRLLQPEYCPDPLY 1313 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEEVGDEH 339 E++ KCW RP FSE++ + I EH Sbjct: 1314 EVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEH 1348
>IGF1R_MOUSE (Q60751) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1373 Score = 57.0 bits (136), Expect = 5e-08 Identities = 31/76 (40%), Positives = 47/76 (61%), Gaps = 1/76 (1%) Frame = +1 Query: 85 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 261 +DV+SFG++LWE+ T + PY+ L+ Q V++ GL P N L EL++ CWQ Sbjct: 1195 SDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDK-PDNCPDMLFELMRMCWQY 1253 Query: 262 DPAERPDFSEILEALK 309 +P RP F EI+ ++K Sbjct: 1254 NPKMRPSFLEIIGSIK 1269
>MET_OTOGA (Q2QLH6) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 57.0 bits (136), Expect = 5e-08 Identities = 33/95 (34%), Positives = 50/95 (52%), Gaps = 1/95 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 ++ + + K+DV+SFG+LLWEL+T G PY + V ++Q G R P+ L Sbjct: 1256 LQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQ-GRRLLQPEYCPDPLY 1314 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEEVGDEH 339 E++ KCW RP FSE++ + I EH Sbjct: 1315 EVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEH 1349
>MET_MICMU (Q2QL89) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 57.0 bits (136), Expect = 5e-08 Identities = 33/95 (34%), Positives = 50/95 (52%), Gaps = 1/95 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 ++ + + K+DV+SFG+LLWEL+T G PY + V ++Q G R P+ L Sbjct: 1256 LQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQ-GRRLLQPEYCPDPLY 1314 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEEVGDEH 339 E++ KCW RP FSE++ + I EH Sbjct: 1315 EVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEH 1349
>IGF1R_RAT (P24062) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1370 Score = 57.0 bits (136), Expect = 5e-08 Identities = 31/76 (40%), Positives = 47/76 (61%), Gaps = 1/76 (1%) Frame = +1 Query: 85 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 261 +DV+SFG++LWE+ T + PY+ L+ Q V++ GL P N L EL++ CWQ Sbjct: 1194 SDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDK-PDNCPDMLFELMRMCWQY 1252 Query: 262 DPAERPDFSEILEALK 309 +P RP F EI+ ++K Sbjct: 1253 NPKMRPSFLEIIGSIK 1268
>HCK_HUMAN (P08631) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p59-HCK/p60-HCK) (Hemopoietic cell kinase) Length = 525 Score = 57.0 bits (136), Expect = 5e-08 Identities = 29/76 (38%), Positives = 47/76 (61%), Gaps = 1/76 (1%) Frame = +1 Query: 82 KADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQ 258 K+DV+SFGILL E++T G+IPY ++ + + +++G R P+N +L ++ +CW+ Sbjct: 436 KSDVWSFGILLMEIVTYGRIPYPGMSNPEV-IRALERGYRMPRPENCPEELYNIMMRCWK 494 Query: 259 QDPAERPDFSEILEAL 306 P ERP F I L Sbjct: 495 NRPEERPTFEYIQSVL 510
>EPHA3_CHICK (P29318) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (CEK4) Length = 983 Score = 57.0 bits (136), Expect = 5e-08 Identities = 29/87 (33%), Positives = 51/87 (58%), Gaps = 1/87 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I ++ + +D +S+GI+LWE+++ G+ PY ++ Q + V +G R P + A L Sbjct: 796 IAYRKFTSASDAWSYGIVLWEVMSYGERPYWEMS-FQDVIKAVDEGYRLPPPMDCPAALY 854 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKI 315 +L+ CWQ+D RP F +I+ L K+ Sbjct: 855 QLMLDCWQKDRNNRPKFEQIVSILDKL 881
>ROS_HUMAN (P08922) Proto-oncogene tyrosine-protein kinase ROS precursor (EC| 2.7.10.1) (c-ros-1) Length = 2347 Score = 57.0 bits (136), Expect = 5e-08 Identities = 32/77 (41%), Positives = 45/77 (58%), Gaps = 1/77 (1%) Frame = +1 Query: 82 KADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQ 258 ++DV+SFGIL+WE+LT G PY + L + VQ G R P+N L L+ +CW Sbjct: 2141 QSDVWSFGILIWEILTLGHQPYPAHSNLDV-LNYVQTGGRLEPPRNCPDDLWNLMTQCWA 2199 Query: 259 QDPAERPDFSEILEALK 309 Q+P +RP F I L+ Sbjct: 2200 QEPDQRPTFHRIQNQLQ 2216
>HCK_MACFA (Q95M30) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 503 Score = 57.0 bits (136), Expect = 5e-08 Identities = 29/76 (38%), Positives = 47/76 (61%), Gaps = 1/76 (1%) Frame = +1 Query: 82 KADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQ 258 K+DV+SFGILL E++T G+IPY ++ + + +++G R P+N +L ++ +CW+ Sbjct: 414 KSDVWSFGILLMEIVTYGRIPYPGMSNPEV-IRALERGYRMPRPENCPEELYNIMMRCWK 472 Query: 259 QDPAERPDFSEILEAL 306 P ERP F I L Sbjct: 473 NRPEERPTFEYIQSVL 488
>YES_XENLA (P10936) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 536 Score = 57.0 bits (136), Expect = 5e-08 Identities = 31/77 (40%), Positives = 47/77 (61%), Gaps = 1/77 (1%) Frame = +1 Query: 82 KADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQ 258 K+DV+SFGILL EL+ G++PY + + + V++G R P+ L EL++ CW+ Sbjct: 445 KSDVWSFGILLTELVAKGRVPYPGMVNREV-LEQVERGYRMPCPQRCPESLHELMKLCWK 503 Query: 259 QDPAERPDFSEILEALK 309 +DP ERP F I L+ Sbjct: 504 KDPDERPTFEYIQSFLE 520
>YES_XIPHE (P27447) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 543 Score = 57.0 bits (136), Expect = 5e-08 Identities = 30/77 (38%), Positives = 48/77 (62%), Gaps = 1/77 (1%) Frame = +1 Query: 82 KADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQ 258 K+DV+SFGILL EL+T G++PY + + + V +G R P+ L E++++CW+ Sbjct: 452 KSDVWSFGILLTELVTKGRVPYPGMVNREV-LEQVDRGYRMPCPQGCPESLHEMMRQCWK 510 Query: 259 QDPAERPDFSEILEALK 309 ++P ERP F I L+ Sbjct: 511 KEPDERPTFEYIQSFLE 527
>EPA4B_XENLA (Q91694) Ephrin type-A receptor 4-B precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor PAG) (Pagliaccio) Length = 985 Score = 57.0 bits (136), Expect = 5e-08 Identities = 27/87 (31%), Positives = 54/87 (62%), Gaps = 1/87 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I ++ + +DV+S+GI++WE+++ G+ PY ++ Q + +++G R P + L Sbjct: 795 IAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSN-QDVIKAIEEGYRLPPPMDCPIALH 853 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKI 315 +L+ CWQ+D ++RP F +I+ L K+ Sbjct: 854 QLMLDCWQKDRSDRPKFGQIVSMLDKL 880
>MET_HORSE (Q2QLA9) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 56.6 bits (135), Expect = 7e-08 Identities = 33/95 (34%), Positives = 50/95 (52%), Gaps = 1/95 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 ++ + + K+DV+SFG+LLWEL+T G PY + V ++Q G R P+ L Sbjct: 1255 LQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQ-GRRLLQPEYCPDPLY 1313 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEEVGDEH 339 E++ KCW RP FSE++ + I EH Sbjct: 1314 EVMLKCWHPKAELRPSFSELVSRISAIFSTFIGEH 1348
>EPHA8_HUMAN (P29322) Ephrin type-A receptor 8 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3) Length = 1005 Score = 56.6 bits (135), Expect = 7e-08 Identities = 29/84 (34%), Positives = 49/84 (58%), Gaps = 1/84 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I + + +DV+SFG+++WE+L G+ PY +T + + V++G R P L Sbjct: 810 IAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTN-RDVISSVEEGYRLPAPMGCPHALH 868 Query: 235 ELLQKCWQQDPAERPDFSEILEAL 306 +L+ CW +D A+RP FS+I+ L Sbjct: 869 QLMLDCWHKDRAQRPRFSQIVSVL 892
>VGFR3_HUMAN (P35916) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1298 Score = 56.6 bits (135), Expect = 7e-08 Identities = 30/89 (33%), Positives = 48/89 (53%), Gaps = 1/89 (1%) Frame = +1 Query: 67 KPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELL 243 K Y ++DV+SFG+LLWE+ + G PY + + ++ G R P+ A + ++ Sbjct: 1089 KVYTTQSDVWSFGVLLWEIFSLGASPYPGVQINEEFCQRLRDGTRMRAPELATPAIRRIM 1148 Query: 244 QKCWQQDPAERPDFSEILEALKKIAEEVG 330 CW DP RP FSE++E L + + G Sbjct: 1149 LNCWSGDPKARPAFSELVEILGDLLQGRG 1177
>ROS_CHICK (P08941) Proto-oncogene tyrosine-protein kinase ROS precursor (EC| 2.7.10.1) (c-ros-1) Length = 2311 Score = 56.6 bits (135), Expect = 7e-08 Identities = 30/82 (36%), Positives = 49/82 (59%), Gaps = 1/82 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 + + +DV++FG+L+WE LT G+ PY L+ ++ + V+ G R P N + +L+ + Sbjct: 2155 FTNHSDVWAFGVLVWETLTLGQQPYPGLSNIEV-LHHVRSGGRLESPNNCPDDIRDLMTR 2213 Query: 250 CWQQDPAERPDFSEILEALKKI 315 CW QDP RP F I L++I Sbjct: 2214 CWAQDPHNRPTFFYIQHKLQEI 2235
>EPHB2_HUMAN (P29323) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen) Length = 1055 Score = 56.6 bits (135), Expect = 7e-08 Identities = 27/87 (31%), Positives = 53/87 (60%), Gaps = 1/87 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I+++ + +DV+S+GI++WE+++ G+ PY +T Q + +++ R P + + L Sbjct: 798 IQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTN-QDVINAIEQDYRLPPPMDCPSALH 856 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKI 315 +L+ CWQ+D RP F +I+ L K+ Sbjct: 857 QLMLDCWQKDRNHRPKFGQIVNTLDKM 883
>SRC2_XENLA (P13116) Tyrosine-protein kinase Src-2 (EC 2.7.10.2) (p60-Src-2)| Length = 531 Score = 56.6 bits (135), Expect = 7e-08 Identities = 32/75 (42%), Positives = 48/75 (64%), Gaps = 1/75 (1%) Frame = +1 Query: 82 KADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQ 258 K+DV+SFGILL EL T G++PY + + + V++G R P + L +L+ +CW+ Sbjct: 440 KSDVWSFGILLTELTTKGRVPYPGMVNREV-LDQVERGYRMPCPPDCPESLHDLMFQCWR 498 Query: 259 QDPAERPDFSEILEA 303 +DP ERP F E L+A Sbjct: 499 KDPEERPTF-EYLQA 512
>SRC1_XENLA (P13115) Tyrosine-protein kinase Src-1 (EC 2.7.10.2) (p60-Src-1)| Length = 531 Score = 56.6 bits (135), Expect = 7e-08 Identities = 32/75 (42%), Positives = 48/75 (64%), Gaps = 1/75 (1%) Frame = +1 Query: 82 KADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQ 258 K+DV+SFGILL EL T G++PY + + + V++G R P + L +L+ +CW+ Sbjct: 440 KSDVWSFGILLTELTTKGRVPYPGMVNREV-LDQVERGYRMPCPPDCPESLHDLMFQCWR 498 Query: 259 QDPAERPDFSEILEA 303 +DP ERP F E L+A Sbjct: 499 KDPEERPTF-EYLQA 512
>EPHA3_MOUSE (P29319) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (MEK4) Length = 983 Score = 56.6 bits (135), Expect = 7e-08 Identities = 29/92 (31%), Positives = 52/92 (56%), Gaps = 1/92 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 + ++ + +DV+S+GI+LWE+++ G+ PY ++ Q + V + R P + A L Sbjct: 796 MSYRKFTSASDVWSYGIVLWEVMSYGERPYSQMSN-QDVIKAVDERYRLPPPMDCPAALY 854 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEEVG 330 +L+ CWQ+D RP F +I+ L K+ G Sbjct: 855 QLMLDCWQKDRNNRPKFEQIVSILDKLIRNPG 886
>ANKK1_MOUSE (Q8BZ25) Ankyrin repeat and protein kinase domain-containing| protein 1 (EC 2.7.11.1) Length = 745 Score = 56.6 bits (135), Expect = 7e-08 Identities = 28/76 (36%), Positives = 45/76 (59%), Gaps = 7/76 (9%) Frame = +1 Query: 88 DVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTI-------PKNAHAKLTELLQ 246 DV+SF I++WE+LT K PY L + + V G+RP++ P+ H ++ L++ Sbjct: 220 DVYSFAIVIWEILTQKKPYAGLNMMTIIIRVA-AGMRPSLQDVSDEWPEEVH-QMVNLMK 277 Query: 247 KCWQQDPAERPDFSEI 294 +CW QDP +RP F + Sbjct: 278 RCWDQDPKKRPCFLNV 293
>SRK4_SPOLA (P42690) Tyrosine-protein kinase isoform SRK4 (EC 2.7.10.2)| Length = 506 Score = 56.6 bits (135), Expect = 7e-08 Identities = 34/93 (36%), Positives = 53/93 (56%), Gaps = 1/93 (1%) Frame = +1 Query: 82 KADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQ 258 K+DV+SFGI+L+E++T G+ PY +T Q + +Q+ R P KL ++ CW+ Sbjct: 415 KSDVWSFGIVLYEVITYGRFPYPGMTNAQV-LEQIQQSYRMPRPMGCPEKLYAIMMDCWR 473 Query: 259 QDPAERPDFSEILEALKKIAEEVGDEHDGKHKD 357 +DPA RP F + L++ GD D +KD Sbjct: 474 EDPASRPTFETLSWQLEEFF-TTGD--DAGYKD 503
>ROS_AVISU (P00529) Tyrosine-protein kinase transforming protein ros (EC| 2.7.10.1) Length = 402 Score = 56.6 bits (135), Expect = 7e-08 Identities = 30/82 (36%), Positives = 49/82 (59%), Gaps = 1/82 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 + + +DV++FG+L+WE LT G+ PY L+ ++ + V+ G R P N + +L+ + Sbjct: 292 FTNHSDVWAFGVLVWETLTLGQQPYPGLSNIEV-LHHVRSGGRLESPNNCPDDIRDLMTR 350 Query: 250 CWQQDPAERPDFSEILEALKKI 315 CW QDP RP F I L++I Sbjct: 351 CWAQDPHNRPTFFYIQHKLQEI 372
>FES_FSVST (P00543) Tyrosine-protein kinase transforming protein Fes (EC| 2.7.10.2) Length = 477 Score = 56.6 bits (135), Expect = 7e-08 Identities = 31/82 (37%), Positives = 46/82 (56%), Gaps = 1/82 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y ++DV+SFGILLWE + G PY L+ Q V+KG R P+ + L+++ Sbjct: 392 YSSESDVWSFGILLWETFSLGASPYPNLSNQQTRE-FVEKGGRLPCPELCPDAVFRLMEQ 450 Query: 250 CWQQDPAERPDFSEILEALKKI 315 CW +P +RP FS + L+ I Sbjct: 451 CWAYEPGQRPSFSAFYQELQSI 472
>KIN16_CAEEL (P34892) Receptor-like tyrosine-protein kinase kin-16 precursor (EC| 2.7.10.1) Length = 495 Score = 56.6 bits (135), Expect = 7e-08 Identities = 28/77 (36%), Positives = 47/77 (61%), Gaps = 1/77 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 + K+DV+SFGI L+E+ T G++PY + P + + G R P++ H +L +L++ Sbjct: 377 FTEKSDVWSFGICLYEIFTLGQLPYPDV-PSERIYEYMHSGRRCPQPQHCHVELYDLMKL 435 Query: 250 CWQQDPAERPDFSEILE 300 CW + P RP+FS +E Sbjct: 436 CWHEKPELRPNFSNCVE 452
>EPHB2_MOUSE (P54763) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3) Length = 994 Score = 56.6 bits (135), Expect = 7e-08 Identities = 27/87 (31%), Positives = 53/87 (60%), Gaps = 1/87 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I+++ + +DV+S+GI++WE+++ G+ PY +T Q + +++ R P + + L Sbjct: 806 IQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTN-QDVINAIEQDYRLPPPMDCPSALH 864 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKI 315 +L+ CWQ+D RP F +I+ L K+ Sbjct: 865 QLMLDCWQKDRNHRPKFGQIVNTLDKM 891
>MET_PIG (Q2QLE0) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 56.2 bits (134), Expect = 9e-08 Identities = 33/95 (34%), Positives = 50/95 (52%), Gaps = 1/95 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 ++ + + K+DV+SFG+LLWEL+T G PY + V ++Q G R P+ L Sbjct: 1255 LQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQ-GRRLLQPEYCPDPLY 1313 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEEVGDEH 339 E++ KCW RP FSE++ + I EH Sbjct: 1314 EVMLKCWHPRAELRPSFSELVSRISAIFSTFIGEH 1348
>SRMS_MOUSE (Q62270) Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70)| Length = 496 Score = 56.2 bits (134), Expect = 9e-08 Identities = 31/85 (36%), Positives = 51/85 (60%), Gaps = 1/85 (1%) Frame = +1 Query: 64 HKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTEL 240 ++ + K+DV+SFGILL+E+ T G+ PYE +T + + + +G R P A++ L Sbjct: 404 YRVFSQKSDVWSFGILLYEVFTYGQCPYEGMTNHET-LQQISRGYRLPRPAVCPAEVYVL 462 Query: 241 LQKCWQQDPAERPDFSEILEALKKI 315 + +CW+ P ERP F+ + E L I Sbjct: 463 MVECWKGSPEERPTFAILREKLNAI 487
>PGFRA_HUMAN (P16234) Alpha platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-alpha) (CD140a antigen) Length = 1089 Score = 56.2 bits (134), Expect = 9e-08 Identities = 30/82 (36%), Positives = 47/82 (57%), Gaps = 4/82 (4%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y +DV+S+GILLWE+ + G PY + ++ G R P +A +++ E++ K Sbjct: 872 YTTLSDVWSYGILLWEIFSLGGTPYPGMMVDSTFYNKIKSGYRMAKPDHATSEVYEIMVK 931 Query: 250 CWQQDPAERPDF---SEILEAL 306 CW +P +RP F SEI+E L Sbjct: 932 CWNSEPEKRPSFYHLSEIVENL 953
>MET_CANFA (Q75ZY9) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 56.2 bits (134), Expect = 9e-08 Identities = 33/95 (34%), Positives = 50/95 (52%), Gaps = 1/95 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 ++ + + K+DV+SFG+LLWEL+T G PY + V ++Q G R P+ L Sbjct: 1256 LQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQ-GRRLLQPEYCPDPLY 1314 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEEVGDEH 339 E++ KCW RP FSE++ + I EH Sbjct: 1315 EVMLKCWHPRAELRPSFSELVSRISAIFSTFIGEH 1349
>LCK_SAISC (Q95KR7) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 56.2 bits (134), Expect = 9e-08 Identities = 31/100 (31%), Positives = 60/100 (60%), Gaps = 1/100 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I + + K+DV+SFGIL+ E++T G+IPY +T + + +++G R P N +L Sbjct: 411 INYGTFTIKSDVWSFGILMTEIVTHGRIPYPGMTNPEV-IQNLERGYRMPRPDNCPEELY 469 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEEVGDEHDGKHK 354 +L+ +CW++ P +RP F + L+ + E+ +G+++ Sbjct: 470 KLMMQCWRERPDDRPTF----DYLRSVLEDFFTATEGQYQ 505
>LCK_AOTNA (Q5PXS1) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 56.2 bits (134), Expect = 9e-08 Identities = 32/100 (32%), Positives = 58/100 (58%), Gaps = 1/100 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I + + K+DV+SFGILL E++T G+IPY +T + + +++G R P N +L Sbjct: 411 INYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEV-IQNLERGYRMVRPDNCPEELY 469 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEEVGDEHDGKHK 354 L+ CW++ P +RP F + L+ + E+ +G+++ Sbjct: 470 HLMMLCWKERPEDRPTF----DYLRSVLEDFFTATEGQYQ 505
>IGF1R_XENLA (O73798) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (xIGF-1R) (xIGFR) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1358 Score = 56.2 bits (134), Expect = 9e-08 Identities = 30/76 (39%), Positives = 47/76 (61%), Gaps = 1/76 (1%) Frame = +1 Query: 85 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 261 +DV+SFG++LWE+ T + PY+ ++ Q V++ GL P N L EL++ CWQ Sbjct: 1189 SDVWSFGVVLWEIATLAEQPYQGMSNEQVLRFVMEGGLLEK-PDNCPDMLFELMRMCWQF 1247 Query: 262 DPAERPDFSEILEALK 309 +P RP F EI+ ++K Sbjct: 1248 NPKMRPSFLEIISSIK 1263
>SRC_AVIST (P14085) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 556 Score = 56.2 bits (134), Expect = 9e-08 Identities = 32/75 (42%), Positives = 47/75 (62%), Gaps = 1/75 (1%) Frame = +1 Query: 82 KADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQ 258 K+DV+SFGILL EL T G++PY + + + V++G R P L +L+ +CW+ Sbjct: 441 KSDVWSFGILLTELTTKGRVPYPGMVNREV-LDQVERGYRMPCPPECPESLHDLMCQCWR 499 Query: 259 QDPAERPDFSEILEA 303 +DP ERP F E L+A Sbjct: 500 KDPEERPTF-EYLQA 513
>SRC_AVISS (P14084) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 567 Score = 56.2 bits (134), Expect = 9e-08 Identities = 32/75 (42%), Positives = 47/75 (62%), Gaps = 1/75 (1%) Frame = +1 Query: 82 KADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQ 258 K+DV+SFGILL EL T G++PY + + + V++G R P L +L+ +CW+ Sbjct: 441 KSDVWSFGILLTELTTKGRVPYPGMVNREV-LDQVERGYRMPCPPECPESLHDLMCQCWR 499 Query: 259 QDPAERPDFSEILEA 303 +DP ERP F E L+A Sbjct: 500 KDPEERPTF-EYLQA 513
>EPHB1_RAT (P09759) Ephrin type-B receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-2) (ELK) Length = 984 Score = 56.2 bits (134), Expect = 9e-08 Identities = 28/87 (32%), Positives = 53/87 (60%), Gaps = 1/87 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I ++ + +DV+S+GI++WE+++ G+ PY ++ Q + +++ R P + A L Sbjct: 796 IAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSN-QDVINAIEQDYRLPPPMDCPAALH 854 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKI 315 +L+ CWQ+D RP F+EI+ L K+ Sbjct: 855 QLMLDCWQKDRNSRPRFAEIVNTLDKM 881
>EPHB1_HUMAN (P54762) Ephrin type-B receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK) Length = 984 Score = 56.2 bits (134), Expect = 9e-08 Identities = 28/87 (32%), Positives = 53/87 (60%), Gaps = 1/87 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I ++ + +DV+S+GI++WE+++ G+ PY ++ Q + +++ R P + A L Sbjct: 796 IAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSN-QDVINAIEQDYRLPPPMDCPAALH 854 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKI 315 +L+ CWQ+D RP F+EI+ L K+ Sbjct: 855 QLMLDCWQKDRNSRPRFAEIVNTLDKM 881
>YES_HUMAN (P07947) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 542 Score = 56.2 bits (134), Expect = 9e-08 Identities = 31/77 (40%), Positives = 46/77 (59%), Gaps = 1/77 (1%) Frame = +1 Query: 82 KADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQ 258 K+DV+SFGIL EL+T G++PY + + + V++G R P+ L EL+ CW+ Sbjct: 451 KSDVWSFGILQTELVTKGRVPYPGMVNREV-LEQVERGYRMPCPQGCPESLHELMNLCWK 509 Query: 259 QDPAERPDFSEILEALK 309 +DP ERP F I L+ Sbjct: 510 KDPDERPTFEYIQSFLE 526
>YES_MOUSE (Q04736) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 540 Score = 56.2 bits (134), Expect = 9e-08 Identities = 31/77 (40%), Positives = 46/77 (59%), Gaps = 1/77 (1%) Frame = +1 Query: 82 KADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQ 258 K+DV+SFGIL EL+T G++PY + + + V++G R P+ L EL+ CW+ Sbjct: 449 KSDVWSFGILQTELVTKGRVPYPGMVNREV-LEQVERGYRMPCPQGCPESLHELMNLCWK 507 Query: 259 QDPAERPDFSEILEALK 309 +DP ERP F I L+ Sbjct: 508 KDPDERPTFEYIQSFLE 524
>EPB1B_XENLA (Q91736) Ephrin type-B receptor 1-B (EC 2.7.10.1) (Tyrosine-protein| kinase receptor XELK) (Fragment) Length = 902 Score = 56.2 bits (134), Expect = 9e-08 Identities = 28/87 (32%), Positives = 52/87 (59%), Gaps = 1/87 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I ++ + +DV+S+GI++WE+++ G+ PY ++ Q + +++ R P + A L Sbjct: 714 IRYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSN-QDVINAIEQDYRLPPPMDCPAALH 772 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKI 315 +L+ CWQ+D RP F EI+ L K+ Sbjct: 773 QLMLDCWQKDRNSRPRFGEIVNTLDKM 799
>SRC_AVIS2 (P15054) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 586 Score = 56.2 bits (134), Expect = 9e-08 Identities = 32/75 (42%), Positives = 47/75 (62%), Gaps = 1/75 (1%) Frame = +1 Query: 82 KADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQ 258 K+DV+SFGILL EL T G++PY + + + V++G R P L +L+ +CW+ Sbjct: 441 KSDVWSFGILLTELTTKGRVPYPGMVNREV-LDQVERGYRMPCPPECPESLHDLMCQCWR 499 Query: 259 QDPAERPDFSEILEA 303 +DP ERP F E L+A Sbjct: 500 KDPEERPTF-EYLQA 513
>EPHA8_MOUSE (O09127) Ephrin type-A receptor 8 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) Length = 1004 Score = 56.2 bits (134), Expect = 9e-08 Identities = 28/84 (33%), Positives = 48/84 (57%), Gaps = 1/84 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I + + +DV+SFG+++WE+L G+ PY +T Q + V++G R P L Sbjct: 809 IAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTN-QDVISSVEEGYRLPAPMGCPRALH 867 Query: 235 ELLQKCWQQDPAERPDFSEILEAL 306 +L+ CW +D A+RP F+ ++ L Sbjct: 868 QLMLDCWHKDRAQRPRFAHVVSVL 891
>SRMS_HUMAN (Q9H3Y6) Tyrosine-protein kinase Srms (EC 2.7.10.2)| Length = 488 Score = 56.2 bits (134), Expect = 9e-08 Identities = 30/85 (35%), Positives = 50/85 (58%), Gaps = 1/85 (1%) Frame = +1 Query: 64 HKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTEL 240 ++ + K+DV+SFG+LL E+ T G+ PYE +T + + + +G R P A++ L Sbjct: 400 YRVFSQKSDVWSFGVLLHEVFTYGQCPYEGMTNHET-LQQIMRGYRLPRPAACPAEVYVL 458 Query: 241 LQKCWQQDPAERPDFSEILEALKKI 315 + +CW+ P ERP F+ + E L I Sbjct: 459 MLECWRSSPEERPSFATLREKLHAI 483
>SRC_CHICK (P00523) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 532 Score = 56.2 bits (134), Expect = 9e-08 Identities = 32/75 (42%), Positives = 47/75 (62%), Gaps = 1/75 (1%) Frame = +1 Query: 82 KADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQ 258 K+DV+SFGILL EL T G++PY + + + V++G R P L +L+ +CW+ Sbjct: 441 KSDVWSFGILLTELTTKGRVPYPGMVNREV-LDQVERGYRMPCPPECPESLHDLMCQCWR 499 Query: 259 QDPAERPDFSEILEA 303 +DP ERP F E L+A Sbjct: 500 KDPEERPTF-EYLQA 513
>MET_HUMAN (P08581) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 55.8 bits (133), Expect = 1e-07 Identities = 32/95 (33%), Positives = 50/95 (52%), Gaps = 1/95 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 ++ + + K+DV+SFG++LWEL+T G PY + V ++Q G R P+ L Sbjct: 1255 LQTQKFTTKSDVWSFGVVLWELMTRGAPPYPDVNTFDITVYLLQ-GRRLLQPEYCPDPLY 1313 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKIAEEVGDEH 339 E++ KCW RP FSE++ + I EH Sbjct: 1314 EVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEH 1348
>FRK_HUMAN (P42685) Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear| tyrosine protein kinase RAK) Length = 505 Score = 55.8 bits (133), Expect = 1e-07 Identities = 28/80 (35%), Positives = 46/80 (57%), Gaps = 1/80 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I + K+DV+SFGILL+E++T GK+PY +T Q + ++ + R P N + Sbjct: 405 IRSNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQ-VIQMLAQNYRLPQPSNCPQQFY 463 Query: 235 ELLQKCWQQDPAERPDFSEI 294 ++ +CW +P ERP F + Sbjct: 464 NIMLECWNAEPKERPTFETL 483
>RIPK1_MOUSE (Q60855) Receptor-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein) Length = 656 Score = 55.8 bits (133), Expect = 1e-07 Identities = 30/87 (34%), Positives = 48/87 (55%), Gaps = 3/87 (3%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIP---KNAHAK 228 I KP + K+DV+SFGI+LW + K PYE + + V ++ G RP + + + Sbjct: 202 INAKPTE-KSDVYSFGIVLWAIFAKKEPYENVICTEQFVICIKSGNRPNVEEILEYCPRE 260 Query: 229 LTELLQKCWQQDPAERPDFSEILEALK 309 + L+++CWQ P +RP F I E + Sbjct: 261 IISLMERCWQAIPEDRPTFLGIEEEFR 287
>EPHA1_HUMAN (P21709) Ephrin type-A receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH) Length = 976 Score = 55.8 bits (133), Expect = 1e-07 Identities = 30/87 (34%), Positives = 51/87 (58%), Gaps = 1/87 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I H+ + +DV+SFGI++WE+L+ G PY ++ Q + ++ G R P + A L Sbjct: 798 IAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSN-QEVMKSIEDGYRLPPPVDCPAPLY 856 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKI 315 EL++ CW D A RP F ++ L+++ Sbjct: 857 ELMKNCWAYDRARRPHFQKLQAHLEQL 883
>RIPK4_HUMAN (P57078) Receptor-interacting serine/threonine-protein kinase 4 (EC| 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase) Length = 832 Score = 55.8 bits (133), Expect = 1e-07 Identities = 30/77 (38%), Positives = 42/77 (54%), Gaps = 6/77 (7%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAK------LT 234 +D K DV+SF I++W +LT K P+ + + V KG RP +P A+ L Sbjct: 200 FDTKHDVYSFAIVIWGVLTQKKPFADEKNILHIMVKVVKGHRPELPPVCRARPRACSHLI 259 Query: 235 ELLQKCWQQDPAERPDF 285 L+Q+CWQ DP RP F Sbjct: 260 RLMQRCWQGDPRVRPTF 276
>YES_CANFA (Q28923) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 538 Score = 55.5 bits (132), Expect = 1e-07 Identities = 31/77 (40%), Positives = 45/77 (58%), Gaps = 1/77 (1%) Frame = +1 Query: 82 KADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQ 258 K+DV+SFGIL EL T G++PY + + + V++G R P+ L EL+ CW+ Sbjct: 447 KSDVWSFGILQTELTTKGRVPYPGMVNREV-LEQVERGYRMPCPQGCPESLHELMNLCWK 505 Query: 259 QDPAERPDFSEILEALK 309 +DP ERP F I L+ Sbjct: 506 KDPDERPTFEYIQSFLE 522
>FAK2_RAT (P70600) Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal| adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) Length = 1009 Score = 55.5 bits (132), Expect = 1e-07 Identities = 29/87 (33%), Positives = 52/87 (59%), Gaps = 1/87 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I + + +DV+ F + +WE+L+ GK P+ +L + +GV++KG R P+ L Sbjct: 597 INFRRFTTASDVWMFAVCMWEILSFGKQPFFWLEN-KDVIGVLEKGDRLPKPELCPPVLY 655 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKI 315 L+ +CW DP++RP F+E++ +L I Sbjct: 656 TLMTRCWDYDPSDRPRFTELVCSLSDI 682
>FAK2_MOUSE (Q9QVP9) Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal| adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinas Length = 1009 Score = 55.5 bits (132), Expect = 1e-07 Identities = 29/87 (33%), Positives = 52/87 (59%), Gaps = 1/87 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I + + +DV+ F + +WE+L+ GK P+ +L + +GV++KG R P+ L Sbjct: 597 INFRRFTTASDVWMFAVCMWEILSFGKQPFFWLEN-KDVIGVLEKGDRLPKPELCPPVLY 655 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKI 315 L+ +CW DP++RP F+E++ +L I Sbjct: 656 TLMTRCWDYDPSDRPRFTELVCSLSDI 682
>M3LK7_DROME (P83104) Putative mitogen-activated protein kinase kinase kinase| 7-like (EC 2.7.11.25) Length = 393 Score = 55.5 bits (132), Expect = 1e-07 Identities = 31/99 (31%), Positives = 51/99 (51%), Gaps = 6/99 (6%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLTGKIPYEYLT------PLQAAVGVVQKGLRPTIPKNA 219 I+H Y K DV+SFGI+LWEL+T ++PY +L + A+ +K + + Sbjct: 178 IKHLKYTAKCDVYSFGIMLWELMTRQLPYSHLENPNSQYAIMKAISSGEKLPMEAVRSDC 237 Query: 220 HAKLTELLQKCWQQDPAERPDFSEILEALKKIAEEVGDE 336 + +L++ C +P +RP EI + L + E DE Sbjct: 238 PEGIKQLMECCMDINPEKRPSMKEIEKFLGEQYESGTDE 276
>EPHA4_MOUSE (Q03137) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK) (MPK-3) Length = 986 Score = 55.5 bits (132), Expect = 1e-07 Identities = 26/87 (29%), Positives = 54/87 (62%), Gaps = 1/87 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I ++ + +DV+S+GI++WE+++ G+ PY ++ Q + +++G R P + L Sbjct: 796 IAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSN-QDVIKAIEEGYRLPPPMDCPIALH 854 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKI 315 +L+ CWQ++ ++RP F +I+ L K+ Sbjct: 855 QLMLDCWQKERSDRPKFGQIVNMLDKL 881
>EPHA4_HUMAN (P54764) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8) Length = 986 Score = 55.5 bits (132), Expect = 1e-07 Identities = 26/87 (29%), Positives = 54/87 (62%), Gaps = 1/87 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I ++ + +DV+S+GI++WE+++ G+ PY ++ Q + +++G R P + L Sbjct: 796 IAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSN-QDVIKAIEEGYRLPPPMDCPIALH 854 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKI 315 +L+ CWQ++ ++RP F +I+ L K+ Sbjct: 855 QLMLDCWQKERSDRPKFGQIVNMLDKL 881
>EPHA4_CHICK (Q07496) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK8) Length = 986 Score = 55.5 bits (132), Expect = 1e-07 Identities = 26/87 (29%), Positives = 54/87 (62%), Gaps = 1/87 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I ++ + +DV+S+GI++WE+++ G+ PY ++ Q + +++G R P + L Sbjct: 796 IAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSN-QDVIKAIEEGYRLPPPMDCPIALH 854 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKI 315 +L+ CWQ++ ++RP F +I+ L K+ Sbjct: 855 QLMLDCWQKERSDRPKFGQIVNMLDKL 881
>EPA4A_XENLA (Q91845) Ephrin type-A receptor 4-A precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK-1) (xSEK-1) Length = 986 Score = 55.5 bits (132), Expect = 1e-07 Identities = 26/87 (29%), Positives = 54/87 (62%), Gaps = 1/87 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I ++ + +DV+S+GI++WE+++ G+ PY ++ Q + +++G R P + L Sbjct: 795 IAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSN-QDVIKAIEEGYRLPPPMDCPIALH 853 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKI 315 +L+ CWQ++ ++RP F +I+ L K+ Sbjct: 854 QLMLDCWQKERSDRPKFGQIVSMLDKL 880
>SRK1_SPOLA (P42686) Tyrosine-protein kinase isoform SRK1 (EC 2.7.10.2)| Length = 505 Score = 55.5 bits (132), Expect = 1e-07 Identities = 27/84 (32%), Positives = 49/84 (58%), Gaps = 1/84 (1%) Frame = +1 Query: 82 KADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQ 258 K+DV+SFG++L+E++T G+ PY +T + + +Q+ R P N + +++ CW+ Sbjct: 415 KSDVWSFGVVLYEIITYGRFPYPGMTNPEV-LEKIQQNYRMPCPANCPKQFHDIMLDCWR 473 Query: 259 QDPAERPDFSEILEALKKIAEEVG 330 +DPA RP F + L++ G Sbjct: 474 EDPASRPTFETLQWQLEEFFNSEG 497
>LCK_MOUSE (P06240) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) Length = 508 Score = 55.5 bits (132), Expect = 1e-07 Identities = 30/84 (35%), Positives = 49/84 (58%), Gaps = 1/84 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I + + K+DV+SFGILL E++T G+IPY +T + + +++G R P N +L Sbjct: 411 INYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEV-IQNLERGYRMVRPDNCPEELY 469 Query: 235 ELLQKCWQQDPAERPDFSEILEAL 306 L+ CW++ P +RP F + L Sbjct: 470 HLMMLCWKERPEDRPTFDYLRSVL 493
>VGFR2_HUMAN (P35968) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Kinase insert domain receptor) (Protein-tyrosine kinase receptor Flk-1) (CD309 antigen) Length = 1356 Score = 55.5 bits (132), Expect = 1e-07 Identities = 29/93 (31%), Positives = 52/93 (55%), Gaps = 1/93 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y ++DV+SFG+LLWE+ + G PY + + +++G R P ++ + + Sbjct: 1082 YTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLD 1141 Query: 250 CWQQDPAERPDFSEILEALKKIAEEVGDEHDGK 348 CW +P++RP FSE++E L + + + DGK Sbjct: 1142 CWHGEPSQRPTFSELVEHLGNLL-QANAQQDGK 1173
>SRC_RSVSE (P63185) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 55.5 bits (132), Expect = 1e-07 Identities = 32/75 (42%), Positives = 47/75 (62%), Gaps = 1/75 (1%) Frame = +1 Query: 82 KADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQ 258 K+DV+SFGILL EL T G++PY + + + V++G R P L +L+ +CW+ Sbjct: 441 KSDVWSFGILLTELTTKGRVPYPGMGNGEV-LDRVERGYRMPCPPECPESLHDLMSQCWR 499 Query: 259 QDPAERPDFSEILEA 303 +DP ERP F E L+A Sbjct: 500 RDPEERPTF-EYLQA 513
>SRC_RSVP (P00526) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 55.5 bits (132), Expect = 1e-07 Identities = 29/69 (42%), Positives = 43/69 (62%), Gaps = 1/69 (1%) Frame = +1 Query: 82 KADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQ 258 K+DV+SFGILL EL T G++PY + + + V++G R P L +L+ +CW+ Sbjct: 441 KSDVWSFGILLTELTTKGRVPYPGMVNREV-LDQVERGYRMPCPPECPESLHDLMCQCWR 499 Query: 259 QDPAERPDF 285 +DP ERP F Sbjct: 500 KDPEERPTF 508
>KFMS_FSVMD (P00545) Tyrosine-protein kinase transforming protein fms (EC| 2.7.10.1) Length = 978 Score = 55.5 bits (132), Expect = 1e-07 Identities = 29/85 (34%), Positives = 46/85 (54%), Gaps = 1/85 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y ++DV+S+GILLWE+ + G PY + +V+ G + P A + ++Q Sbjct: 864 YTVQSDVWSYGILLWEIFSLGLNPYPGILVNSKFYKLVKDGYQMAQPAFAPKNIYSIMQA 923 Query: 250 CWQQDPAERPDFSEILEALKKIAEE 324 CW +P RP F +I L+K A+E Sbjct: 924 CWALEPTRRPTFQQICSLLQKQAQE 948
>INSR_XENLA (Q9PVZ4) Insulin receptor precursor (EC 2.7.10.1) (IR) (Xe-InsR)| (XTK-1b) [Contains: Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1362 Score = 55.5 bits (132), Expect = 1e-07 Identities = 30/76 (39%), Positives = 46/76 (60%), Gaps = 1/76 (1%) Frame = +1 Query: 85 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 261 +DV+SFG++LWE+ + + PY+ L+ Q V+ G P+N +L L+Q CWQ Sbjct: 1206 SDVWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGSLDH-PENCPPRLHSLMQMCWQY 1264 Query: 262 DPAERPDFSEILEALK 309 +P RP F EI++ LK Sbjct: 1265 NPKMRPTFLEIIDMLK 1280
>EPHA1_MOUSE (Q60750) Ephrin type-A receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ESK) Length = 977 Score = 55.5 bits (132), Expect = 1e-07 Identities = 30/87 (34%), Positives = 51/87 (58%), Gaps = 1/87 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I H+ + +DV+SFGI++WE+L+ G PY ++ Q + ++ G R P + A L Sbjct: 799 IAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSN-QEVMKSIEDGYRLPPPVDCPAPLY 857 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKI 315 EL++ CW D A RP F ++ L+++ Sbjct: 858 ELMKNCWAYDRARRPHFLQLQAHLEQL 884
>CSF1R_FELCA (P13369) Macrophage colony-stimulating factor 1 receptor precursor| (CSF-1-R) (EC 2.7.10.1) (Fms proto-oncogene) (c-fms) Length = 980 Score = 55.5 bits (132), Expect = 1e-07 Identities = 29/85 (34%), Positives = 46/85 (54%), Gaps = 1/85 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y ++DV+S+GILLWE+ + G PY + +V+ G + P A + ++Q Sbjct: 830 YTVQSDVWSYGILLWEIFSLGLNPYPGILVNSKFYKLVKDGYQMAQPAFAPKNIYSIMQA 889 Query: 250 CWQQDPAERPDFSEILEALKKIAEE 324 CW +P RP F +I L+K A+E Sbjct: 890 CWALEPTRRPTFQQICSLLQKQAQE 914
>EPHB2_COTJA (Q90344) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor QEK5) Length = 987 Score = 55.5 bits (132), Expect = 1e-07 Identities = 27/87 (31%), Positives = 52/87 (59%), Gaps = 1/87 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I+++ + +DV+S+GI++WE+++ G+ PY +T Q + +++ R P + L Sbjct: 799 IQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTN-QDVINAIEQDYRLPPPMDCPNALH 857 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKI 315 +L+ CWQ+D RP F +I+ L K+ Sbjct: 858 QLMLDCWQKDRNHRPKFGQIVNTLDKM 884
>EPHB2_CHICK (P28693) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK5) Length = 1004 Score = 55.5 bits (132), Expect = 1e-07 Identities = 27/87 (31%), Positives = 52/87 (59%), Gaps = 1/87 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 I+++ + +DV+S+GI++WE+++ G+ PY +T Q + +++ R P + L Sbjct: 816 IQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTN-QDVINAIEQDYRLPPPMDCPNALH 874 Query: 235 ELLQKCWQQDPAERPDFSEILEALKKI 315 +L+ CWQ+D RP F +I+ L K+ Sbjct: 875 QLMLDCWQKDRNHRPKFGQIVNTLDKM 901
>MERTK_RAT (P57097) Proto-oncogene tyrosine-protein kinase MER precursor (EC| 2.7.10.1) (C-mer) (Receptor tyrosine kinase MerTK) Length = 994 Score = 55.5 bits (132), Expect = 1e-07 Identities = 30/91 (32%), Positives = 49/91 (53%), Gaps = 1/91 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y K+DV++FG+ +WE+ T G PY + + + G R P++ L E++ Sbjct: 772 YTSKSDVWAFGVTMWEIATRGMTPYPGVQNHEM-YDYLLHGHRLKQPEDCLDDLYEIMYS 830 Query: 250 CWQQDPAERPDFSEILEALKKIAEEVGDEHD 342 CW DP +RP FS + L+K++E + D D Sbjct: 831 CWSADPLDRPTFSVLRLQLEKLSESLPDAQD 861
>VGFR2_COTJA (P52583) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Endothelial kinase receptor EK1) (Quek 1) (Quek1) Length = 1348 Score = 55.1 bits (131), Expect = 2e-07 Identities = 30/93 (32%), Positives = 50/93 (53%), Gaps = 1/93 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y ++DV+SFG+LLWE+ + G PY + + +++G R P ++ + + Sbjct: 1075 YTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLD 1134 Query: 250 CWQQDPAERPDFSEILEALKKIAEEVGDEHDGK 348 CW DP +RP FSE++E L + + DGK Sbjct: 1135 CWHGDPKQRPTFSELVEHLGNLL-QANVRQDGK 1166
>SRC_RSVPA (P31693) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 522 Score = 55.1 bits (131), Expect = 2e-07 Identities = 32/75 (42%), Positives = 47/75 (62%), Gaps = 1/75 (1%) Frame = +1 Query: 82 KADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQ 258 K+DV+SFGILL EL T G++PY + + + V++G R P L +L+ +CW+ Sbjct: 438 KSDVWSFGILLTELTTKGRVPYPGMVNGEV-LDRVERGYRMPCPPECPESLHDLMCQCWR 496 Query: 259 QDPAERPDFSEILEA 303 +DP ERP F E L+A Sbjct: 497 KDPEERPTF-EYLQA 510
>PKN2_CLOAB (Q97IC2) Probable serine/threonine protein kinase CAC1728 (EC| 2.7.11.1) Length = 657 Score = 55.1 bits (131), Expect = 2e-07 Identities = 30/95 (31%), Positives = 55/95 (57%), Gaps = 4/95 (4%) Frame = +1 Query: 70 PYDHKADVFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRP--TIPKNAHAKLTELL 243 P D + D++SFGI+L+E+ TGK+PY+ TP+ A+ +Q P + K+ L +++ Sbjct: 185 PVDCRTDIYSFGIVLYEMATGKVPYDADTPVSIALKHIQDAAVPPNELNKDIPIALNKMI 244 Query: 244 QKCWQQDPAER-PDFSEILEALKKIAEE-VGDEHD 342 +C ++ P R + +EIL+ L + V D+ + Sbjct: 245 LRCIEKKPENRYQNANEILDELSNVKNNYVNDDEE 279
>CSF1R_HUMAN (P07333) Macrophage colony-stimulating factor 1 receptor precursor| (CSF-1-R) (EC 2.7.10.1) (Fms proto-oncogene) (c-fms) (CD115 antigen) Length = 972 Score = 55.1 bits (131), Expect = 2e-07 Identities = 30/91 (32%), Positives = 48/91 (52%), Gaps = 1/91 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y ++DV+S+GILLWE+ + G PY + +V+ G + P A + ++Q Sbjct: 832 YTVQSDVWSYGILLWEIFSLGLNPYPGILVNSKFYKLVKDGYQMAQPAFAPKNIYSIMQA 891 Query: 250 CWQQDPAERPDFSEILEALKKIAEEVGDEHD 342 CW +P RP F +I L++ A+E E D Sbjct: 892 CWALEPTHRPTFQQICSFLQEQAQEDRRERD 922
>PTK7_HUMAN (Q13308) Tyrosine-protein kinase-like 7 precursor (Colon carcinoma| kinase 4) (CCK-4) Length = 1070 Score = 55.1 bits (131), Expect = 2e-07 Identities = 31/85 (36%), Positives = 48/85 (56%), Gaps = 7/85 (8%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPY------EYLTPLQAAVGVVQKGLRPTIPKNAHAKL 231 + K+DV++ G+L+WE+ T G++P+ E L LQA + + P+ +KL Sbjct: 983 FSTKSDVWASGVLMWEVFTHGEMPHGGQADDEVLADLQAGKARLPQ------PEGCPSKL 1036 Query: 232 TELLQKCWQQDPAERPDFSEILEAL 306 L+Q+CW P +RP FSEI AL Sbjct: 1037 YRLMQRCWALSPKDRPSFSEIASAL 1061
>LET23_CAEEL (P24348) Receptor tyrosine-protein kinase let-23 precursor (EC| 2.7.10.1) (Lethal protein 23) Length = 1367 Score = 55.1 bits (131), Expect = 2e-07 Identities = 27/84 (32%), Positives = 46/84 (54%), Gaps = 1/84 (1%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y H +DV++FG+ WE++T G+ PY+ ++ + ++ G R + P N L + L + Sbjct: 1108 YTHASDVWAFGVTCWEIITFGQSPYQGMST-DSIHNFLKDGNRLSQPPNCSQDLYQELLR 1166 Query: 250 CWQQDPAERPDFSEILEALKKIAE 321 CW DP RP F + E K+ + Sbjct: 1167 CWMADPKSRPGFEILYERFKEFCK 1190
>PGFRA_XENLA (P26619) Alpha platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-alpha) Length = 1087 Score = 55.1 bits (131), Expect = 2e-07 Identities = 29/82 (35%), Positives = 47/82 (57%), Gaps = 4/82 (4%) Frame = +1 Query: 73 YDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 249 Y +DV+SFGILLWE+ + G PY + ++ G R P +A ++ +++ K Sbjct: 872 YTTLSDVWSFGILLWEIFSLGGTPYPGMIVDSTFYNKIKSGYRMAKPDHATHEVYDIMVK 931 Query: 250 CWQQDPAERPDF---SEILEAL 306 CW +P +RP F S+I+E+L Sbjct: 932 CWNSEPEKRPSFRHLSDIVESL 953
>TOR_DROME (P18475) Tyrosine-protein kinase receptor torso precursor (EC| 2.7.10.1) Length = 923 Score = 55.1 bits (131), Expect = 2e-07 Identities = 27/84 (32%), Positives = 50/84 (59%), Gaps = 1/84 (1%) Frame = +1 Query: 58 IEHKPYDHKADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLT 234 + H+ Y ++DV+SFG+LL+E+ T G +PY ++P + ++++G R P+ ++ Sbjct: 791 LTHQVYTSQSDVWSFGVLLYEITTLGGMPYPSVSPSDL-LQLLRQGHRMKRPEGCTQEMF 849 Query: 235 ELLQKCWQQDPAERPDFSEILEAL 306 L++ CW P+ RP FS + L Sbjct: 850 SLMESCWSSVPSHRPTFSALKHRL 873
>INSRR_HUMAN (P14616) Insulin receptor-related protein precursor (EC 2.7.10.1)| (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] Length = 1297 Score = 55.1 bits (131), Expect = 2e-07 Identities = 27/77 (35%), Positives = 50/77 (64%), Gaps = 1/77 (1%) Frame = +1 Query: 85 ADVFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQ 261 +DV+SFG++LWE++T + PY+ L+ Q V+ G+ + + +L EL+ +CWQ Sbjct: 1173 SDVWSFGVVLWEIVTLAEQPYQGLSNEQVLKFVMDGGVLEEL-EGCPLQLQELMSRCWQP 1231 Query: 262 DPAERPDFSEILEALKK 312 +P RP F+ IL+++++ Sbjct: 1232 NPRLRPSFTHILDSIQE 1248 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 97,511,439 Number of Sequences: 219361 Number of extensions: 2002564 Number of successful extensions: 6705 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 5978 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6220 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 6598423128 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
