ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | baal32b06 |
|---|---|
| Clone Library Name | barley_pub |
>BAK1_ARATH (Q94F62) BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1| precursor (EC 2.7.11.1) (BRI1-associated receptor kinase 1) (Somatic embryogenesis receptor-like kinase 3) Length = 615 Score = 293 bits (749), Expect = 2e-79 Identities = 146/161 (90%), Positives = 152/161 (94%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 ANILLDE+FEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG Sbjct: 420 ANILLDEEFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 479 Query: 181 IMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEALI 360 +MLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKK+E LVD DLQ Y + EVE LI Sbjct: 480 VMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKLEALVDVDLQGNYKDEEVEQLI 539 Query: 361 QVALLCTQGSPMDRPKMSEVVRMLEGDGLAERWEEWQKVEV 483 QVALLCTQ SPM+RPKMSEVVRMLEGDGLAERWEEWQK E+ Sbjct: 540 QVALLCTQSSPMERPKMSEVVRMLEGDGLAERWEEWQKEEM 580
>CX32_ARATH (P27450) Probable serine/threonine-protein kinase Cx32, chloroplast| precursor (EC 2.7.11.1) Length = 419 Score = 107 bits (268), Expect = 1e-23 Identities = 57/147 (38%), Positives = 91/147 (61%), Gaps = 2/147 (1%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKD-THVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGY 177 +NILLD +++A + DFGLAKL + +HVTT + GT G+ APEY++TG K+DVF + Sbjct: 222 SNILLDSNYDAKLSDFGLAKLGPADEKSHVTTRIMGTYGYAAPEYMATGHLYVKSDVFAF 281 Query: 178 GIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEK-KVEMLVDPDLQSVYVEHEVEA 354 G++LLE++TG A + R + L+DW++ L K +V+ ++D ++ Y Sbjct: 282 GVVLLEIMTGLTAHNTKRPRGQES--LVDWLRPELSNKHRVKQIMDKGIKGQYTTKVATE 339 Query: 355 LIQVALLCTQGSPMDRPKMSEVVRMLE 435 + ++ L C + P +RP M EVV +LE Sbjct: 340 MARITLSCIEPDPKNRPHMKEVVEVLE 366
>RLCK7_ARATH (Q9LQQ8) Probable serine/threonine-protein kinase RLCKVII (EC| 2.7.11.1) Length = 423 Score = 107 bits (267), Expect = 2e-23 Identities = 58/146 (39%), Positives = 91/146 (62%), Gaps = 2/146 (1%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKD-THVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGY 177 +NILL ED++ + DFGLAK+ D THV+T V GT G+ AP+Y TG+ + K+D++ + Sbjct: 234 SNILLGEDYQPKLSDFGLAKVGPSGDKTHVSTRVMGTYGYCAPDYAMTGQLTFKSDIYSF 293 Query: 178 GIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKK-VEMLVDPDLQSVYVEHEVEA 354 G++LLELITG++A D + D + L+ W + L K+++ +VDP LQ Y + Sbjct: 294 GVVLLELITGRKAIDNTKTRKDQN--LVGWARPLFKDRRNFPKMVDPLLQGQYPVRGLYQ 351 Query: 355 LIQVALLCTQGSPMDRPKMSEVVRML 432 + ++ +C Q P RP +S+VV L Sbjct: 352 ALAISAMCVQEQPTMRPVVSDVVLAL 377
>EXS_ARATH (Q9LYN8) Leucine-rich repeat receptor protein kinase EXS precursor| (EC 2.7.11.1) (Extra sporogenous cells protein) (EXCESS MICROSPOROCYTES1 protein) Length = 1192 Score = 105 bits (261), Expect = 8e-23 Identities = 54/145 (37%), Positives = 89/145 (61%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 +NILLD DFE V DFGLA+L+ ++HV+T + GT G+I PEY + +++ K DV+ +G Sbjct: 1047 SNILLDGDFEPKVADFGLARLISACESHVSTVIAGTFGYIPPEYGQSARATTKGDVYSFG 1106 Query: 181 IMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEALI 360 ++LLEL+TG+ + L+ W + + K ++DP L SV +++ L+ Sbjct: 1107 VILLELVTGKEPTG-PDFKESEGGNLVGWAIQKINQGKAVDVIDPLLVSVALKNSQLRLL 1165 Query: 361 QVALLCTQGSPMDRPKMSEVVRMLE 435 Q+A+LC +P RP M +V++ L+ Sbjct: 1166 QIAMLCLAETPAKRPNMLDVLKALK 1190
>PSKR_ARATH (Q9ZVR7) Putative phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1008 Score = 103 bits (256), Expect = 3e-22 Identities = 53/145 (36%), Positives = 88/145 (60%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 +NILLDE+F + + DFGLA+LM +THV+T + GT+G+I PEY ++ K DV+ +G Sbjct: 864 SNILLDENFNSHLADFGLARLMSPYETHVSTDLVGTLGYIPPEYGQASVATYKGDVYSFG 923 Query: 181 IMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEALI 360 ++LLEL+T +R D+ + D L+ WV + E + + DP + S + E+ ++ Sbjct: 924 VVLLELLTDKRPVDMCKPKGCRD--LISWVVKMKHESRASEVFDPLIYSKENDKEMFRVL 981 Query: 361 QVALLCTQGSPMDRPKMSEVVRMLE 435 ++A LC +P RP ++V L+ Sbjct: 982 EIACLCLSENPKQRPTTQQLVSWLD 1006
>APK1A_ARATH (Q06548) Protein kinase APK1A, chloroplast precursor (EC 2.7.11.1)| Length = 410 Score = 103 bits (256), Expect = 3e-22 Identities = 61/147 (41%), Positives = 92/147 (62%), Gaps = 2/147 (1%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKD-THVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGY 177 +NILLD ++ A + DFGLAK D +HV+T V GT G+ APEYL+TG + K+DV+ + Sbjct: 207 SNILLDSEYNAKLSDFGLAKDGPIGDKSHVSTRVMGTHGYAAPEYLATGHLTTKSDVYSF 266 Query: 178 GIMLLELITGQRAFDLARLANDDDVMLLDWVKG-LLKEKKVEMLVDPDLQSVYVEHEVEA 354 G++LLEL++G+RA D R + + + L++W K L+ ++K+ ++D LQ Y E Sbjct: 267 GVVLLELLSGRRAVDKNRPSGERN--LVEWAKPYLVNKRKIFRVIDNRLQDQYSMEEACK 324 Query: 355 LIQVALLCTQGSPMDRPKMSEVVRMLE 435 + ++L C RP MSEVV LE Sbjct: 325 VATLSLRCLTTEIKLRPNMSEVVSHLE 351
>BRL1_ARATH (Q9ZWC8) Serine/threonine-protein kinase BRI1-like 1 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 1) Length = 1166 Score = 102 bits (253), Expect = 7e-22 Identities = 53/147 (36%), Positives = 91/147 (61%), Gaps = 2/147 (1%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTA-VRGTIGHIAPEYLSTGKSSEKTDVFGY 177 +N+LLDEDFEA V DFG+A+L+ DTH++ + + GT G++ PEY + + + K DV+ Y Sbjct: 991 SNVLLDEDFEARVSDFGMARLVSALDTHLSVSTLAGTPGYVPPEYYQSFRCTAKGDVYSY 1050 Query: 178 GIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDL-QSVYVEHEVEA 354 G++LLEL++G++ D D++ L+ W K L +EK+ ++DP+L + E+ Sbjct: 1051 GVILLELLSGKKPIDPGEFGEDNN--LVGWAKQLYREKRGAEILDPELVTDKSGDVELFH 1108 Query: 355 LIQVALLCTQGSPMDRPKMSEVVRMLE 435 +++A C P RP M +++ M + Sbjct: 1109 YLKIASQCLDDRPFKRPTMIQLMAMFK 1135
>RLK5_ARATH (P47735) Receptor-like protein kinase 5 precursor (EC 2.7.11.1)| Length = 999 Score = 102 bits (253), Expect = 7e-22 Identities = 57/148 (38%), Positives = 92/148 (62%), Gaps = 3/148 (2%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAK---LMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVF 171 +NILLD D+ A V DFG+AK + K + + G+ G+IAPEY+ T + +EK+D++ Sbjct: 823 SNILLDSDYGAKVADFGIAKVGQMSGSKTPEAMSGIAGSCGYIAPEYVYTLRVNEKSDIY 882 Query: 172 GYGIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVE 351 +G++LLEL+TG++ D + L + D + WV L + +E ++DP L + E E+ Sbjct: 883 SFGVVLLELVTGKQPTD-SELGDKD---MAKWVCTALDKCGLEPVIDPKLDLKFKE-EIS 937 Query: 352 ALIQVALLCTQGSPMDRPKMSEVVRMLE 435 +I + LLCT P++RP M +VV ML+ Sbjct: 938 KVIHIGLLCTSPLPLNRPSMRKVVIMLQ 965
>APK1B_ARATH (P46573) Protein kinase APK1B, chloroplast precursor (EC 2.7.11.1)| Length = 412 Score = 102 bits (253), Expect = 7e-22 Identities = 61/147 (41%), Positives = 89/147 (60%), Gaps = 2/147 (1%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKD-THVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGY 177 +NILLD ++ A + DFGLAK D +HV+T + GT G+ APEYL+TG + K+DV+ Y Sbjct: 208 SNILLDSEYNAKLSDFGLAKDGPTGDKSHVSTRIMGTYGYAAPEYLATGHLTTKSDVYSY 267 Query: 178 GIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEK-KVEMLVDPDLQSVYVEHEVEA 354 G++LLE+++G+RA D R + L++W + LL K K+ ++D LQ Y E Sbjct: 268 GVVLLEVLSGRRAVDKNRPPGEQ--KLVEWARPLLANKRKLFRVIDNRLQDQYSMEEACK 325 Query: 355 LIQVALLCTQGSPMDRPKMSEVVRMLE 435 + +AL C RP M+EVV LE Sbjct: 326 VATLALRCLTFEIKLRPNMNEVVSHLE 352
>NORK_MEDTR (Q8L4H4) Nodulation receptor kinase precursor (EC 2.7.11.1) (Does not| make infections protein 2) (Symbiosis receptor-like kinase) (MtSYMRK) Length = 925 Score = 100 bits (250), Expect = 2e-21 Identities = 54/146 (36%), Positives = 90/146 (61%), Gaps = 1/146 (0%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYK-DTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGY 177 +NILLD+ A V DFG +K + D++V+ VRGT G++ PEY T + SEK+DVF + Sbjct: 726 SNILLDQSMCAKVADFGFSKYAPQEGDSYVSLEVRGTAGYLDPEYYKTQQLSEKSDVFSF 785 Query: 178 GIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEAL 357 G++LLE+++G+ ++ R + L++W K ++ KV+ +VDP ++ Y + + Sbjct: 786 GVVLLEIVSGREPLNIKR--PRIEWSLVEWAKPYIRASKVDEIVDPGIKGGYHAEALWRV 843 Query: 358 IQVALLCTQGSPMDRPKMSEVVRMLE 435 ++VAL C + RP M ++VR LE Sbjct: 844 VEVALQCLEPYSTYRPCMVDIVRELE 869
>NAK_ARATH (P43293) Probable serine/threonine-protein kinase NAK (EC 2.7.11.1)| Length = 389 Score = 100 bits (249), Expect = 2e-21 Identities = 58/147 (39%), Positives = 90/147 (61%), Gaps = 2/147 (1%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKD-THVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGY 177 +NILLD ++ A + DFGLA+ D +HV+T V GT G+ APEYL+TG S K+DV+ + Sbjct: 207 SNILLDSNYNAKLSDFGLARDGPMGDNSHVSTRVMGTQGYAAPEYLATGHLSVKSDVYSF 266 Query: 178 GIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEK-KVEMLVDPDLQSVYVEHEVEA 354 G++LLEL++G+RA D + + + L+DW + L K ++ ++DP LQ Y Sbjct: 267 GVVLLELLSGRRAIDKNQPVGEHN--LVDWARPYLTNKRRLLRVMDPRLQGQYSLTRALK 324 Query: 355 LIQVALLCTQGSPMDRPKMSEVVRMLE 435 + +AL C RP M+E+V+ +E Sbjct: 325 IAVLALDCISIDAKSRPTMNEIVKTME 351
>PSKR_DAUCA (Q8LPB4) Phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1021 Score = 100 bits (248), Expect = 3e-21 Identities = 54/145 (37%), Positives = 85/145 (58%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 +NILL + F A + DFGLA+L+ DTHVTT + GT+G+I PEY ++ K DV+ +G Sbjct: 873 SNILLSDTFVAHLADFGLARLILPYDTHVTTDLVGTLGYIPPEYGQASVATYKGDVYSFG 932 Query: 181 IMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEALI 360 ++LLEL+TG+R D+ + D L+ WV + EK+ + DP + E+ ++ Sbjct: 933 VVLLELLTGRRPMDVCKPRGSRD--LISWVLQMKTEKRESEIFDPFIYDKDHAEEMLLVL 990 Query: 361 QVALLCTQGSPMDRPKMSEVVRMLE 435 ++A C +P RP ++V LE Sbjct: 991 EIACRCLGENPKTRPTTQQLVSWLE 1015
>NORK_PEA (Q8LKZ1) Nodulation receptor kinase precursor (EC 2.7.11.1)| Length = 924 Score = 100 bits (248), Expect = 3e-21 Identities = 54/146 (36%), Positives = 89/146 (60%), Gaps = 1/146 (0%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYK-DTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGY 177 +NILLD A V DFG +K + D++V+ VRGT G++ PEY T + SEK+DVF + Sbjct: 725 SNILLDHSMCAKVADFGFSKYAPQEGDSYVSLEVRGTAGYLDPEYYKTQQLSEKSDVFSF 784 Query: 178 GIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEAL 357 G++LLE+++G+ ++ R + L++W K ++ KV+ +VDP ++ Y + + Sbjct: 785 GVVLLEIVSGREPLNIKR--PRVEWSLVEWAKPYIRASKVDEIVDPGIKGGYHAEALWRV 842 Query: 358 IQVALLCTQGSPMDRPKMSEVVRMLE 435 ++VAL C + RP M ++VR LE Sbjct: 843 VEVALQCLEPYSTYRPCMVDIVRELE 868
>BRL3_ARATH (Q9LJF3) Serine/threonine-protein kinase BRI1-like 3 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 3) Length = 1164 Score = 99.8 bits (247), Expect = 3e-21 Identities = 54/148 (36%), Positives = 92/148 (62%), Gaps = 3/148 (2%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTA-VRGTIGHIAPEYLSTGKSSEKTDVFGY 177 +N+LLD+DF A V DFG+A+L+ DTH++ + + GT G++ PEY + + + K DV+ Y Sbjct: 989 SNVLLDQDFVARVSDFGMARLVSALDTHLSVSTLAGTPGYVPPEYYQSFRCTAKGDVYSY 1048 Query: 178 GIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEAL 357 G++LLEL++G++ D D++ L+ W K L +EK+ ++DP+L + +VE L Sbjct: 1049 GVILLELLSGKKPIDPEEFGEDNN--LVGWAKQLYREKRGAEILDPELVT-DKSGDVELL 1105 Query: 358 --IQVALLCTQGSPMDRPKMSEVVRMLE 435 +++A C P RP M +V+ M + Sbjct: 1106 HYLKIASQCLDDRPFKRPTMIQVMTMFK 1133
>PBS1_ARATH (Q9FE20) Serine/threonine-protein kinase PBS1 (EC 2.7.11.1)| (AvrPphB susceptible protein 1) Length = 456 Score = 97.1 bits (240), Expect = 2e-20 Identities = 57/146 (39%), Positives = 85/146 (58%), Gaps = 2/146 (1%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKD-THVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGY 177 +NILLDE F + DFGLAKL D +HV+T V GT G+ APEY TG+ + K+DV+ + Sbjct: 217 SNILLDEGFHPKLSDFGLAKLGPTGDKSHVSTRVMGTYGYCAPEYAMTGQLTVKSDVYSF 276 Query: 178 GIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKE-KKVEMLVDPDLQSVYVEHEVEA 354 G++ LELITG++A D + + L+ W + L + +K L DP L+ + + Sbjct: 277 GVVFLELITGRKAIDSEMPHGEQN--LVAWARPLFNDRRKFIKLADPRLKGRFPTRALYQ 334 Query: 355 LIQVALLCTQGSPMDRPKMSEVVRML 432 + VA +C Q RP +++VV L Sbjct: 335 ALAVASMCIQEQAATRPLIADVVTAL 360
>BRI1_ARATH (O22476) BRASSINOSTEROID INSENSITIVE 1 precursor (EC 2.7.11.1)| (AtBRI1) (Brassinosteroid LRR receptor kinase) Length = 1196 Score = 95.9 bits (237), Expect = 5e-20 Identities = 56/148 (37%), Positives = 89/148 (60%), Gaps = 3/148 (2%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTA-VRGTIGHIAPEYLSTGKSSEKTDVFGY 177 +N+LLDE+ EA V DFG+A+LM DTH++ + + GT G++ PEY + + S K DV+ Y Sbjct: 1013 SNVLLDENLEARVSDFGMARLMSAMDTHLSVSTLAGTPGYVPPEYYQSFRCSTKGDVYSY 1072 Query: 178 GIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEAL 357 G++LLEL+TG+R D +++ L+ WVK K ++ + DP+L E+E L Sbjct: 1073 GVVLLELLTGKRPTDSPDFGDNN---LVGWVKQHAK-LRISDVFDPELMKEDPALEIELL 1128 Query: 358 --IQVALLCTQGSPMDRPKMSEVVRMLE 435 ++VA+ C RP M +V+ M + Sbjct: 1129 QHLKVAVACLDDRAWRRPTMVQVMAMFK 1156
>BRI1_LYCPE (Q8L899) Systemin receptor SR160 precursor (EC 2.7.11.1)| (Brassinosteroid LRR receptor kinase) Length = 1207 Score = 94.0 bits (232), Expect = 2e-19 Identities = 56/148 (37%), Positives = 89/148 (60%), Gaps = 3/148 (2%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTA-VRGTIGHIAPEYLSTGKSSEKTDVFGY 177 +N+LLDE+ EA V DFG+A+LM DTH++ + + GT G++ PEY + + S K DV+ Y Sbjct: 1018 SNVLLDENLEARVSDFGMARLMSAMDTHLSVSTLAGTPGYVPPEYYQSFRCSTKGDVYSY 1077 Query: 178 GIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEAL 357 G++LLEL+TG++ D A +++ L+ WVK L + K+ + D +L E+E L Sbjct: 1078 GVVLLELLTGKQPTDSADFGDNN---LVGWVK-LHAKGKITDVFDRELLKEDASIEIELL 1133 Query: 358 --IQVALLCTQGSPMDRPKMSEVVRMLE 435 ++VA C RP M +V+ M + Sbjct: 1134 QHLKVACACLDDRHWKRPTMIQVMAMFK 1161
>BRI1_LYCES (Q8GUQ5) Brassinosteroid LRR receptor kinase precursor (EC 2.7.11.1)| (tBRI1) (Altered brassinolide sensitivity 1) (Systemin receptor SR160) Length = 1207 Score = 94.0 bits (232), Expect = 2e-19 Identities = 56/148 (37%), Positives = 89/148 (60%), Gaps = 3/148 (2%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTA-VRGTIGHIAPEYLSTGKSSEKTDVFGY 177 +N+LLDE+ EA V DFG+A+LM DTH++ + + GT G++ PEY + + S K DV+ Y Sbjct: 1018 SNVLLDENLEARVSDFGMARLMSAMDTHLSVSTLAGTPGYVPPEYYQSFRCSTKGDVYSY 1077 Query: 178 GIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEAL 357 G++LLEL+TG++ D A +++ L+ WVK L + K+ + D +L E+E L Sbjct: 1078 GVVLLELLTGKQPTDSADFGDNN---LVGWVK-LHAKGKITDVFDRELLKEDASIEIELL 1133 Query: 358 --IQVALLCTQGSPMDRPKMSEVVRMLE 435 ++VA C RP M +V+ M + Sbjct: 1134 QHLKVACACLDDRHWKRPTMIQVMAMFK 1161
>RPK1_IPONI (P93194) Receptor-like protein kinase precursor (EC 2.7.11.1)| Length = 1109 Score = 93.2 bits (230), Expect = 3e-19 Identities = 54/149 (36%), Positives = 87/149 (58%), Gaps = 6/149 (4%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHV-TTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 NILLD D E + DFG+AKL+D T + + V+GTIG++APE T S ++DV+ YG Sbjct: 947 NILLDSDLEPHISDFGIAKLLDQSATSIPSNTVQGTIGYMAPENAFTTVKSRESDVYSYG 1006 Query: 181 IMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEK-KVEMLVDPDLQSVYVE----HE 345 ++LLELIT ++A D + D ++ WV+ + + +++ +VDP L ++ + Sbjct: 1007 VVLLELITRKKALDPSFNGETD---IVGWVRSVWTQTGEIQKIVDPSLLDELIDSSVMEQ 1063 Query: 346 VEALIQVALLCTQGSPMDRPKMSEVVRML 432 V + +AL C + RP M +VV+ L Sbjct: 1064 VTEALSLALRCAEKEVDKRPTMRDVVKQL 1092
>SIRK_ARATH (O64483) Senescence-induced receptor-like serine/threonine-protein| kinase precursor (FLG22-induced receptor-like kinase 1) Length = 876 Score = 92.4 bits (228), Expect = 6e-19 Identities = 52/145 (35%), Positives = 87/145 (60%), Gaps = 1/145 (0%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDT-HVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 NILL+E +A + DFGL++ + + ++T V G+IG++ PEY ST + +EK+DV+ G Sbjct: 702 NILLNEKLQAKMADFGLSRSFSVEGSGQISTVVAGSIGYLDPEYYSTRQMNEKSDVYSLG 761 Query: 181 IMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEALI 360 ++LLE+ITGQ A ++ + V + D V+ +L + +VD L+ Y + Sbjct: 762 VVLLEVITGQPAIASSK---TEKVHISDHVRSILANGDIRGIVDQRLRERYDVGSAWKMS 818 Query: 361 QVALLCTQGSPMDRPKMSEVVRMLE 435 ++AL CT+ + RP MS+VV L+ Sbjct: 819 EIALACTEHTSAQRPTMSQVVMELK 843
>TMK1_ARATH (P43298) Putative receptor protein kinase TMK1 precursor (EC| 2.7.11.1) Length = 942 Score = 90.5 bits (223), Expect = 2e-18 Identities = 54/160 (33%), Positives = 88/160 (55%), Gaps = 6/160 (3%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 +NILL +D A V DFGL +L + T + GT G++APEY TG+ + K DV+ +G Sbjct: 721 SNILLGDDMRAKVADFGLVRLAPEGKGSIETRIAGTFGYLAPEYAVTGRVTTKVDVYSFG 780 Query: 181 IMLLELITGQRAFDLARLANDDDVMLLDWVKGLL--KE----KKVEMLVDPDLQSVYVEH 342 ++L+ELITG+++ D ++ ++ + L+ W K + KE K ++ +D D +++ H Sbjct: 781 VILMELITGRKSLDESQ--PEESIHLVSWFKRMYINKEASFKKAIDTTIDLDEETLASVH 838 Query: 343 EVEALIQVALLCTQGSPMDRPKMSEVVRMLEGDGLAERWE 462 V ++A C P RP M V +L L E W+ Sbjct: 839 TV---AELAGHCCAREPYQRPDMGHAVNIL--SSLVELWK 873
>CLV1_ARATH (Q9SYQ8) Receptor protein kinase CLAVATA1 precursor (EC 2.7.11.1)| Length = 980 Score = 90.1 bits (222), Expect = 3e-18 Identities = 59/151 (39%), Positives = 85/151 (56%), Gaps = 8/151 (5%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAK-LMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 NILLD DFEA V DFGLAK L+D + +++ G+ G+IAPEY T K EK+DV+ +G Sbjct: 822 NILLDSDFEAHVADFGLAKFLVDGAASECMSSIAGSYGYIAPEYAYTLKVDEKSDVYSFG 881 Query: 181 IMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKE-------KKVEMLVDPDLQSVYVE 339 ++LLELI G++ + V ++ WV+ +E V +VDP L Y Sbjct: 882 VVLLELIAGKKPVG----EFGEGVDIVRWVRNTEEEITQPSDAAIVVAIVDPRLTG-YPL 936 Query: 340 HEVEALIQVALLCTQGSPMDRPKMSEVVRML 432 V + ++A++C + RP M EVV ML Sbjct: 937 TSVIHVFKIAMMCVEEEAAARPTMREVVHML 967
>SRK6_BRAOE (Q09092) Putative serine/threonine-protein kinase receptor precursor| (EC 2.7.11.1) (S-receptor kinase) (SRK) Length = 849 Score = 90.1 bits (222), Expect = 3e-18 Identities = 55/151 (36%), Positives = 86/151 (56%), Gaps = 8/151 (5%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTA-VRGTIGHIAPEYLSTGKSSEKTDVFGY 177 +NILLD++ + DFG+A++ + +T T V GT G+++PEY G SEK+DVF + Sbjct: 657 SNILLDKNMIPKISDFGMARIFERDETEANTMKVVGTYGYMSPEYAMYGIFSEKSDVFSF 716 Query: 178 GIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDL-------QSVYV 336 G+++LE+++G++ L ++D LL +V KE + +VDP + S++ Sbjct: 717 GVIVLEIVSGKKNRGFYNLDYEND--LLSYVWSRWKEGRALEIVDPVIVDSLSSQPSIFQ 774 Query: 337 EHEVEALIQVALLCTQGSPMDRPKMSEVVRM 429 EV IQ+ LLC Q RP MS VV M Sbjct: 775 PQEVLKCIQIGLLCVQELAEHRPAMSSVVWM 805
>BRL2_ARATH (Q9ZPS9) Serine/threonine-protein kinase BRI1-like 2 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 2) (Protein VASCULAR HIGHWAY 1) Length = 1143 Score = 87.4 bits (215), Expect = 2e-17 Identities = 51/160 (31%), Positives = 85/160 (53%), Gaps = 16/160 (10%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTA-VRGTIGHIAPEYLSTGKSSEKTDVFGY 177 +N+LLD+D EA V DFG+A+L+ DTH++ + + GT G++ PEY + + + K DV+ Sbjct: 970 SNVLLDQDMEARVSDFGMARLISALDTHLSVSTLAGTPGYVPPEYYQSFRCTAKGDVYSI 1029 Query: 178 GIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDL------------ 321 G+++LE+++G+R D D L+ W K +E K ++D DL Sbjct: 1030 GVVMLEILSGKRPTDKEEFG---DTNLVGWSKMKAREGKHMEVIDEDLLKEGSSESLNEK 1086 Query: 322 ---QSVYVEHEVEALIQVALLCTQGSPMDRPKMSEVVRML 432 + + E+ +++AL C P RP M +VV L Sbjct: 1087 EGFEGGVIVKEMLRYLEIALRCVDDFPSKRPNMLQVVASL 1126
>KPRO_MAIZE (P17801) Putative receptor protein kinase ZmPK1 precursor (EC| 2.7.11.1) Length = 817 Score = 81.6 bits (200), Expect = 1e-15 Identities = 52/150 (34%), Positives = 82/150 (54%), Gaps = 7/150 (4%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYK-DTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 NILLD+ FE + DFGL KL++ T + VRGT+G+IAPE++S+ + K DV+ YG Sbjct: 663 NILLDQAFEPKITDFGLVKLLNRGGSTQNVSHVRGTLGYIAPEWVSSLPITAKVDVYSYG 722 Query: 181 IMLLELITGQRAFDLARLANDDDVMLLDWVKGLL------KEKKVEMLVDPDLQSVYVEH 342 ++LLEL+TG R +L ++ ML V+ L ++ ++ +D L Sbjct: 723 VVLLELLTGTRVSELVGGTDEVHSMLRKLVRMLSAKLEGEEQSWIDGYLDSKLNRPVNYV 782 Query: 343 EVEALIQVALLCTQGSPMDRPKMSEVVRML 432 + LI++A+ C + RP M V+ L Sbjct: 783 QARTLIKLAVSCLEEDRSKRPTMEHAVQTL 812
>CRI4_MAIZE (O24585) Putative receptor protein kinase CRINKLY4 precursor (EC| 2.7.11.1) Length = 901 Score = 79.3 bits (194), Expect = 5e-15 Identities = 46/146 (31%), Positives = 80/146 (54%), Gaps = 1/146 (0%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKD-THVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGY 177 +NIL+DED A V DFGL+ L T ++ GT+G++ PEY + K+DV+ + Sbjct: 638 SNILIDEDHNARVADFGLSILGPADSGTPLSELPAGTLGYLDPEYYRLHYLTTKSDVYSF 697 Query: 178 GIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEAL 357 G++LLE+++G++A D+ ++ +++W L+K + ++DP L ++ + Sbjct: 698 GVVLLEILSGRKAIDM----QFEEGNIVEWAVPLIKAGDIFAILDPVLSPPSDLEALKKI 753 Query: 358 IQVALLCTQGSPMDRPKMSEVVRMLE 435 VA C + DRP M +V LE Sbjct: 754 ASVACKCVRMRGKDRPSMDKVTTALE 779
>IRAK4_HUMAN (Q9NWZ3) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) (NY-REN-64 antigen) Length = 460 Score = 76.6 bits (187), Expect = 3e-14 Identities = 52/147 (35%), Positives = 84/147 (57%), Gaps = 2/147 (1%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMD-YKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGY 177 ANILLDE F A + DFGLA+ + + T +T+ + GT ++APE L G+ + K+D++ + Sbjct: 315 ANILLDEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPEALR-GEITPKSDIYSF 373 Query: 178 GIMLLELITGQRAFDLARLANDDDVMLLDWVKGLL-KEKKVEMLVDPDLQSVYVEHEVEA 354 G++LLE+ITG A D R + +LLD + + +EK +E +D + VEA Sbjct: 374 GVVLLEIITGLPAVDEHR----EPQLLLDIKEEIEDEEKTIEDYIDKKMNDA-DSTSVEA 428 Query: 355 LIQVALLCTQGSPMDRPKMSEVVRMLE 435 + VA C RP + +V ++L+ Sbjct: 429 MYSVASQCLHEKKNKRPDIKKVQQLLQ 455
>IRAK4_MOUSE (Q8R4K2) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) Length = 459 Score = 74.7 bits (182), Expect = 1e-13 Identities = 51/146 (34%), Positives = 80/146 (54%), Gaps = 1/146 (0%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMD-YKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGY 177 ANILLD+DF A + DFGLA+ T +T+ + GT ++APE L G+ + K+D++ + Sbjct: 315 ANILLDKDFTAKISDFGLARASARLAQTVMTSRIVGTTAYMAPEALR-GEITPKSDIYSF 373 Query: 178 GIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEAL 357 G++LLELITG A D N + +LLD + + E+K + S VEA+ Sbjct: 374 GVVLLELITGLAAVD----ENREPQLLLDIKEEIEDEEKTIEDYTDEKMSDADPASVEAM 429 Query: 358 IQVALLCTQGSPMDRPKMSEVVRMLE 435 A C RP +++V ++L+ Sbjct: 430 YSAASQCLHEKKNRRPDIAKVQQLLQ 455
>IRAK1_MOUSE (Q62406) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK) Length = 710 Score = 68.9 bits (167), Expect = 7e-12 Identities = 52/188 (27%), Positives = 79/188 (42%), Gaps = 34/188 (18%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHV--------TTAVRGTIGHIAPEYLSTGKSSE 156 +N+LLDE +GDFGLA+ + T+ VRGT+ ++ EY+ TG+ + Sbjct: 344 SNVLLDERLMPKLGDFGLARFSRFAGAKASQSSTVARTSTVRGTLAYLPEEYIKTGRLAV 403 Query: 157 KTDVFGYGIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKV------------- 297 TD F +G+++LE + GQRA R L D ++ +E V Sbjct: 404 DTDTFSFGVVILETLAGQRA---VRTQGAKTKYLKDLIEDEAEEAGVTLKSTQPTLWVGV 460 Query: 298 --EMLVDPDLQSVYVEHEVE-----------ALIQVALLCTQGSPMDRPKMSEVVRMLEG 438 + P +Y +H AL Q+A C RP M++V + LEG Sbjct: 461 ATDAWAAPIAAQIYKKHLDSRPGPCPPQLGLALAQLACCCMHRRAKKRPPMTQVYKRLEG 520 Query: 439 DGLAERWE 462 WE Sbjct: 521 LQAGPPWE 528
>KPEL_DROME (Q05652) Probable serine/threonine-protein kinase pelle (EC| 2.7.11.1) Length = 501 Score = 67.0 bits (162), Expect = 3e-11 Identities = 48/148 (32%), Positives = 77/148 (52%), Gaps = 3/148 (2%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTA--VRGTIGHIAPEYLSTGKSSEKTDVFG 174 ANILLD+ + +GDFGL + V V GT ++ PE+ + + S DV+ Sbjct: 350 ANILLDQCLQPKIGDFGLVREGPKSLDAVVEVNKVFGTKIYLPPEFRNFRQLSTGVDVYS 409 Query: 175 YGIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEV-E 351 +GI+LLE+ TG++ D N+ LLD+VK ++ ++E+L + E ++ Sbjct: 410 FGIVLLEVFTGRQVTDRVP-ENETKKNLLDYVKQQWRQNRMELLEKHLAAPMGKELDMCM 468 Query: 352 ALIQVALLCTQGSPMDRPKMSEVVRMLE 435 I+ L CT P DRP M+ V++ E Sbjct: 469 CAIEAGLHCTALDPQDRPSMNAVLKRFE 496
>IRAK1_HUMAN (P51617) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) Length = 712 Score = 61.2 bits (147), Expect = 1e-09 Identities = 30/80 (37%), Positives = 47/80 (58%), Gaps = 8/80 (10%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHV--------TTAVRGTIGHIAPEYLSTGKSSE 156 +N+LLDE +GDFGLA+ + + T VRGT+ ++ EY+ TG+ + Sbjct: 344 SNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAV 403 Query: 157 KTDVFGYGIMLLELITGQRA 216 TD F +G+++LE + GQRA Sbjct: 404 DTDTFSFGVVVLETLAGQRA 423
>PK1_STRTO (Q9KIG4) Serine/threonine-protein kinase PK-1 (EC 2.7.11.1)| (stoPK-1) Length = 641 Score = 58.9 bits (141), Expect = 7e-09 Identities = 27/73 (36%), Positives = 45/73 (61%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 N+L+ +D V DFGL + +D T+ T V GT+ ++APE + G + + DV+ GI Sbjct: 146 NVLIGDDGRVKVADFGLVRAVD-SVTNTTGTVLGTVSYLAPEQIEHGTADPRVDVYACGI 204 Query: 184 MLLELITGQRAFD 222 +L E++TG++ D Sbjct: 205 LLYEMLTGEKPHD 217
>CHK1_YEAST (P38147) Serine/threonine-protein kinase CHK1 (EC 2.7.11.1)| (Checkpoint kinase 1) Length = 527 Score = 57.4 bits (137), Expect = 2e-08 Identities = 34/91 (37%), Positives = 53/91 (58%), Gaps = 4/91 (4%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKD--THVTTAVRGTIGHIAPE--YLSTGKSSEKTDVF 171 NILLD++ + DFGLA KD V+ RG+ ++APE Y G +++TD++ Sbjct: 147 NILLDKNGNLKLADFGLASQFRRKDGTLRVSMDQRGSPPYMAPEVLYSEEGYYADRTDIW 206 Query: 172 GYGIMLLELITGQRAFDLARLANDDDVMLLD 264 GI+L L+TGQ ++L L N+D V ++ Sbjct: 207 SIGILLFVLLTGQTPWELPSLENEDFVFFIE 237
>TMKL1_ARATH (P33543) Putative kinase-like protein TMKL1 precursor| Length = 674 Score = 57.4 bits (137), Expect = 2e-08 Identities = 46/148 (31%), Positives = 76/148 (51%), Gaps = 4/148 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 N+L+D+ F A + +FGL K+M + + G+ APE K + ++DV+ +GI Sbjct: 505 NVLVDDFFFARLTEFGLDKIMVQAVADEIVSQAKSDGYKAPELHKMKKCNPRSDVYAFGI 564 Query: 184 MLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPD----LQSVYVEHEVE 351 +LLE++ G++ R N + V L VK + E+ + D + ++S E V Sbjct: 565 LLLEILMGKKPGKSGRNGN-EFVDLPSLVKAAVLEETTMEVFDLEAMKGIRSPMEEGLVH 623 Query: 352 ALIQVALLCTQGSPMDRPKMSEVVRMLE 435 AL ++A+ C RP M EVV+ LE Sbjct: 624 AL-KLAMGCCAPVTTVRPSMEEVVKQLE 650
>YR831_MIMIV (Q7T6Y2) Putative serine/threonine-protein kinase/receptor R831| precursor (EC 2.7.11.1) Length = 1624 Score = 57.0 bits (136), Expect = 3e-08 Identities = 45/144 (31%), Positives = 67/144 (46%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 ANIL+DE F + DFG A++ K+ + T GT APE + K EK DVF +G Sbjct: 1491 ANILVDEHFNVKIADFGFARI---KEDNTTMTRCGTPCWTAPEVIRGEKYCEKADVFSFG 1547 Query: 181 IMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEALI 360 +++ E++TG+ F + LD ++G ++ D HE LI Sbjct: 1548 VVMWEVLTGKEPFAECNFMK----VSLDILEG------GRPIIPSD-----CPHEFAKLI 1592 Query: 361 QVALLCTQGSPMDRPKMSEVVRML 432 + C RP M+EVV+ L Sbjct: 1593 K---KCWHAKAHKRPTMTEVVQQL 1613 Score = 45.8 bits (107), Expect = 6e-05 Identities = 30/75 (40%), Positives = 41/75 (54%), Gaps = 3/75 (4%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTT-AVRGTIGHIAPEYL--STGKSSEKTDVFG 174 N+LLD + V DFGL K+ D T + GTI IAPE L ST DV+ Sbjct: 913 NLLLDSKWNVKVSDFGLTKVKSELDKKKTNDNIIGTIHWIAPEILNDSTEVDYILADVYS 972 Query: 175 YGIMLLELITGQRAF 219 +GI+L EL+T ++ + Sbjct: 973 FGIILWELLTREQPY 987
>IRAK3_HUMAN (Q9Y616) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 596 Score = 55.5 bits (132), Expect = 8e-08 Identities = 41/158 (25%), Positives = 79/158 (50%), Gaps = 13/158 (8%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKD-----THVTTAVRGTIGHIAPEYLSTGKSSEKTD 165 ANILLD+ F+ + DF +A + + ++T++ + ++ EY+ GK S KTD Sbjct: 297 ANILLDDQFQPKLTDFAMAHFRSHLEHQSCTINMTSSSSKHLWYMPEEYIRQGKLSIKTD 356 Query: 166 VFGYGIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHE 345 V+ +GI+++E++TG R L + + L D ++ L++++ ++ + +++ + Sbjct: 357 VYSFGIVIMEVLTGCRVV----LDDPKHIQLRDLLRELMEKRGLDSCLS------FLDKK 406 Query: 346 V--------EALIQVALLCTQGSPMDRPKMSEVVRMLE 435 V L +A C RP M EV+ LE Sbjct: 407 VPPCPRNFSAKLFCLAGRCAATRAKLRPSMDEVLNTLE 444
>MET_RAT (P97523) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 54.3 bits (129), Expect = 2e-07 Identities = 47/144 (32%), Positives = 70/144 (48%), Gaps = 4/144 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLM---DYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFG 174 N +LDE F V DFGLA+ M +Y H T + + +A E L T K + K+DV+ Sbjct: 1210 NCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWS 1269 Query: 175 YGIMLLELIT-GQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVE 351 +G++L EL+T G + DV D LL+ ++ L+ P E+ + Sbjct: 1270 FGVLLWELMTRGAPPY--------PDVNTFDITIYLLQGRR---LLQP-------EYCPD 1311 Query: 352 ALIQVALLCTQGSPMDRPKMSEVV 423 AL +V L C RP +SE+V Sbjct: 1312 ALYEVMLKCWHPKAEMRPSVSELV 1335
>MET_MOUSE (P16056) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1379 Score = 53.9 bits (128), Expect = 2e-07 Identities = 47/144 (32%), Positives = 69/144 (47%), Gaps = 4/144 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLM---DYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFG 174 N +LDE F V DFGLA+ M +Y H T + + +A E L T K + K+DV+ Sbjct: 1207 NCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWS 1266 Query: 175 YGIMLLELIT-GQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVE 351 +G++L EL+T G + DV D LL+ ++ L+ P E+ + Sbjct: 1267 FGVLLWELMTRGAPPY--------PDVNTFDITIYLLQGRR---LLQP-------EYCPD 1308 Query: 352 ALIQVALLCTQGSPMDRPKMSEVV 423 AL +V L C RP SE+V Sbjct: 1309 ALYEVMLKCWHPKAEMRPSFSELV 1332
>PKN6_MYXXA (P54738) Serine/threonine-protein kinase pkn6 (EC 2.7.11.1)| Length = 710 Score = 53.9 bits (128), Expect = 2e-07 Identities = 26/73 (35%), Positives = 40/73 (54%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 NIL+ V DFG+AK+ +T V+G + ++ PE L + DV+ G+ Sbjct: 148 NILVSRQGAVKVVDFGIAKVAGQGHRTLTGVVKGKVAYMPPEQLQAKAMDRRVDVYALGV 207 Query: 184 MLLELITGQRAFD 222 +L EL+TG+R FD Sbjct: 208 VLYELLTGKRPFD 220
>PKN2_BACSU (O34507) Probable serine/threonine-protein kinase yloP (EC| 2.7.11.1) Length = 648 Score = 53.5 bits (127), Expect = 3e-07 Identities = 26/73 (35%), Positives = 44/73 (60%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 NIL+D V DFG+A + T +V G++ +++PE G +++K+D++ GI Sbjct: 139 NILIDHMGNIKVTDFGIATALSSTTITHTNSVLGSVHYLSPEQARGGLATKKSDIYALGI 198 Query: 184 MLLELITGQRAFD 222 +L EL+TG+ FD Sbjct: 199 VLFELLTGRIPFD 211
>MET_OTOGA (Q2QLH6) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 53.1 bits (126), Expect = 4e-07 Identities = 46/144 (31%), Positives = 69/144 (47%), Gaps = 4/144 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLM---DYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFG 174 N +LDE+F V DFGLA+ M +Y H T + + +A E L T K + K+DV+ Sbjct: 1210 NCMLDENFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWS 1269 Query: 175 YGIMLLELIT-GQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVE 351 +G++L EL+T G + DV D LL+ ++ L+ P E+ + Sbjct: 1270 FGVLLWELMTRGAPPY--------PDVNTFDITVYLLQGRR---LLQP-------EYCPD 1311 Query: 352 ALIQVALLCTQGSPMDRPKMSEVV 423 L +V L C RP SE+V Sbjct: 1312 PLYEVMLKCWHPKAEMRPSFSELV 1335
>PLK1_RAT (Q62673) Serine/threonine-protein kinase PLK1 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-1) Length = 603 Score = 52.8 bits (125), Expect = 5e-07 Identities = 43/140 (30%), Positives = 67/140 (47%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 N+ L+ED E +GDFGLA ++Y+ T + GT +IAPE LS S + DV+ G Sbjct: 181 NLFLNEDLEVKIGDFGLATKVEYEGERKKT-LCGTPNYIAPEVLSKKGHSFEVDVWSIGC 239 Query: 184 MLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEALIQ 363 ++ L+ G+ F+ + L + L+ KK E + + V +LIQ Sbjct: 240 IMYTLLVGKPPFETSCLK-----------ETYLRIKKNEYSIPKHINPV-----AASLIQ 283 Query: 364 VALLCTQGSPMDRPKMSEVV 423 L Q P RP + E++ Sbjct: 284 KML---QTDPAARPTIHELL 300
>PLK1_MOUSE (Q07832) Serine/threonine-protein kinase PLK1 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13) Length = 603 Score = 52.8 bits (125), Expect = 5e-07 Identities = 43/140 (30%), Positives = 67/140 (47%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 N+ L+ED E +GDFGLA ++Y+ T + GT +IAPE LS S + DV+ G Sbjct: 181 NLFLNEDLEVKIGDFGLATKVEYEGERKKT-LCGTPNYIAPEVLSKKGHSFEVDVWSIGC 239 Query: 184 MLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEALIQ 363 ++ L+ G+ F+ + L + L+ KK E + + V +LIQ Sbjct: 240 IMYTLLVGKPPFETSCLK-----------ETYLRIKKNEYSIPKHINPV-----AASLIQ 283 Query: 364 VALLCTQGSPMDRPKMSEVV 423 L Q P RP + E++ Sbjct: 284 KML---QTDPTARPTIHELL 300
>PLK1_HUMAN (P53350) Serine/threonine-protein kinase PLK1 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13) Length = 603 Score = 52.8 bits (125), Expect = 5e-07 Identities = 43/140 (30%), Positives = 67/140 (47%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 N+ L+ED E +GDFGLA ++Y D + GT +IAPE LS S + DV+ G Sbjct: 181 NLFLNEDLEVKIGDFGLATKVEY-DGERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGC 239 Query: 184 MLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEALIQ 363 ++ L+ G+ F+ + L + L+ KK E + + V +LIQ Sbjct: 240 IMYTLLVGKPPFETSCLK-----------ETYLRIKKNEYSIPKHINPV-----AASLIQ 283 Query: 364 VALLCTQGSPMDRPKMSEVV 423 L Q P RP ++E++ Sbjct: 284 KML---QTDPTARPTINELL 300
>MET_MICMU (Q2QL89) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 52.4 bits (124), Expect = 6e-07 Identities = 46/144 (31%), Positives = 68/144 (47%), Gaps = 4/144 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLM---DYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFG 174 N +LDE F V DFGLA+ M +Y H T + + +A E L T K + K+DV+ Sbjct: 1210 NCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWS 1269 Query: 175 YGIMLLELIT-GQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVE 351 +G++L EL+T G + DV D LL+ ++ L+ P E+ + Sbjct: 1270 FGVLLWELMTRGAPPY--------PDVNTFDITVYLLQGRR---LLQP-------EYCPD 1311 Query: 352 ALIQVALLCTQGSPMDRPKMSEVV 423 L +V L C RP SE+V Sbjct: 1312 PLYEVMLKCWHPKAEMRPSFSELV 1335
>MET_PONPY (Q2IBD8) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 52.4 bits (124), Expect = 6e-07 Identities = 46/144 (31%), Positives = 68/144 (47%), Gaps = 4/144 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLM---DYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFG 174 N +LDE F V DFGLA+ M +Y H T + + +A E L T K + K+DV+ Sbjct: 1209 NCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWS 1268 Query: 175 YGIMLLELIT-GQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVE 351 +G++L EL+T G + DV D LL+ ++ L+ P E+ + Sbjct: 1269 FGVLLWELMTRGAPPY--------PDVNTFDITVYLLQGRR---LLQP-------EYCPD 1310 Query: 352 ALIQVALLCTQGSPMDRPKMSEVV 423 L +V L C RP SE+V Sbjct: 1311 PLYEVMLKCWHPKAEMRPSFSELV 1334
>MET_PANTR (Q2QLF1) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 52.4 bits (124), Expect = 6e-07 Identities = 46/144 (31%), Positives = 68/144 (47%), Gaps = 4/144 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLM---DYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFG 174 N +LDE F V DFGLA+ M +Y H T + + +A E L T K + K+DV+ Sbjct: 1209 NCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWS 1268 Query: 175 YGIMLLELIT-GQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVE 351 +G++L EL+T G + DV D LL+ ++ L+ P E+ + Sbjct: 1269 FGVLLWELMTRGAPPY--------PDVNTFDITVYLLQGRR---LLQP-------EYCPD 1310 Query: 352 ALIQVALLCTQGSPMDRPKMSEVV 423 L +V L C RP SE+V Sbjct: 1311 PLYEVMLKCWHPKAEMRPSFSELV 1334
>LCK_HUMAN (P06239) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell-specific protein-tyrosine kinase) Length = 508 Score = 52.4 bits (124), Expect = 6e-07 Identities = 40/145 (27%), Positives = 68/145 (46%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 ANIL+ + + DFGLA+L++ + + I APE ++ G + K+DV+ +G Sbjct: 367 ANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFG 426 Query: 181 IMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEALI 360 I+L E++T R + N + + L+ + +V PD + E L Sbjct: 427 ILLTEIVTHGR-IPYPGMTNPEVIQNLE---------RGYRMVRPD-------NCPEELY 469 Query: 361 QVALLCTQGSPMDRPKMSEVVRMLE 435 Q+ LC + P DRP + +LE Sbjct: 470 QLMRLCWKERPEDRPTFDYLRSVLE 494
>MET_CALMO (Q2QLC0) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 52.4 bits (124), Expect = 6e-07 Identities = 46/144 (31%), Positives = 68/144 (47%), Gaps = 4/144 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLM---DYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFG 174 N +LDE F V DFGLA+ M +Y H T + + +A E L T K + K+DV+ Sbjct: 1209 NCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWS 1268 Query: 175 YGIMLLELIT-GQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVE 351 +G++L EL+T G + DV D LL+ ++ L+ P E+ + Sbjct: 1269 FGVLLWELMTRGAPPY--------PDVNTFDITVYLLQGRR---LLQP-------EYCPD 1310 Query: 352 ALIQVALLCTQGSPMDRPKMSEVV 423 L +V L C RP SE+V Sbjct: 1311 PLYEVMLKCWHPKAEMRPSFSELV 1334
>MET_CALJA (Q2QLG5) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 52.4 bits (124), Expect = 6e-07 Identities = 46/144 (31%), Positives = 68/144 (47%), Gaps = 4/144 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLM---DYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFG 174 N +LDE F V DFGLA+ M +Y H T + + +A E L T K + K+DV+ Sbjct: 1209 NCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWS 1268 Query: 175 YGIMLLELIT-GQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVE 351 +G++L EL+T G + DV D LL+ ++ L+ P E+ + Sbjct: 1269 FGVLLWELMTRGAPPY--------PDVNTFDITVYLLQGRR---LLQP-------EYCPD 1310 Query: 352 ALIQVALLCTQGSPMDRPKMSEVV 423 L +V L C RP SE+V Sbjct: 1311 PLYEVMLKCWHPKAEMRPSFSELV 1334
>PKNL_MYCTU (O53510) Probable serine/threonine-protein kinase pknL (EC| 2.7.11.1) Length = 399 Score = 52.0 bits (123), Expect = 8e-07 Identities = 22/72 (30%), Positives = 41/72 (56%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 NIL+ +D + + DFGL + + T + GT +++PE + G + ++DV+ G+ Sbjct: 147 NILISDDGDVKLADFGLVRAVAAASITSTGVILGTAAYLSPEQVRDGNADPRSDVYSVGV 206 Query: 184 MLLELITGQRAF 219 ++ EL+TG F Sbjct: 207 LVYELLTGHTPF 218
>PKNL_MYCBO (Q7TYY6) Probable serine/threonine-protein kinase pknL (EC| 2.7.11.1) Length = 399 Score = 52.0 bits (123), Expect = 8e-07 Identities = 22/72 (30%), Positives = 41/72 (56%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 NIL+ +D + + DFGL + + T + GT +++PE + G + ++DV+ G+ Sbjct: 147 NILISDDGDVKLADFGLVRAVAAASITSTGVILGTAAYLSPEQVRDGNADPRSDVYSVGV 206 Query: 184 MLLELITGQRAF 219 ++ EL+TG F Sbjct: 207 LVYELLTGHTPF 218
>MET_HUMAN (P08581) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 52.0 bits (123), Expect = 8e-07 Identities = 46/144 (31%), Positives = 68/144 (47%), Gaps = 4/144 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLM---DYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFG 174 N +LDE F V DFGLA+ M +Y H T + + +A E L T K + K+DV+ Sbjct: 1209 NCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWS 1268 Query: 175 YGIMLLELIT-GQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVE 351 +G++L EL+T G + DV D LL+ ++ L+ P E+ + Sbjct: 1269 FGVVLWELMTRGAPPY--------PDVNTFDITVYLLQGRR---LLQP-------EYCPD 1310 Query: 352 ALIQVALLCTQGSPMDRPKMSEVV 423 L +V L C RP SE+V Sbjct: 1311 PLYEVMLKCWHPKAEMRPSFSELV 1334
>LCK_AOTNA (Q5PXS1) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 52.0 bits (123), Expect = 8e-07 Identities = 39/145 (26%), Positives = 68/145 (46%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 ANIL+ + + DFGLA+L++ + + I APE ++ G + K+DV+ +G Sbjct: 367 ANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFG 426 Query: 181 IMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEALI 360 I+L E++T R + N + + L+ + +V PD + E L Sbjct: 427 ILLTEIVTHGR-IPYPGMTNPEVIQNLE---------RGYRMVRPD-------NCPEELY 469 Query: 361 QVALLCTQGSPMDRPKMSEVVRMLE 435 + +LC + P DRP + +LE Sbjct: 470 HLMMLCWKERPEDRPTFDYLRSVLE 494
>MET_HORSE (Q2QLA9) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 52.0 bits (123), Expect = 8e-07 Identities = 46/144 (31%), Positives = 68/144 (47%), Gaps = 4/144 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLM---DYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFG 174 N +LDE F V DFGLA+ M +Y H T + + +A E L T K + K+DV+ Sbjct: 1209 NCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWS 1268 Query: 175 YGIMLLELIT-GQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVE 351 +G++L EL+T G + DV D LL+ ++ L+ P E+ + Sbjct: 1269 FGVLLWELMTRGAPPY--------PDVNTFDITVYLLQGRR---LLQP-------EYCPD 1310 Query: 352 ALIQVALLCTQGSPMDRPKMSEVV 423 L +V L C RP SE+V Sbjct: 1311 PLYEVMLKCWHPKAELRPSFSELV 1334
>MET_CANFA (Q75ZY9) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 51.6 bits (122), Expect = 1e-06 Identities = 46/144 (31%), Positives = 68/144 (47%), Gaps = 4/144 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLM---DYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFG 174 N +LDE F V DFGLA+ M +Y H T + + +A E L T K + K+DV+ Sbjct: 1210 NCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWS 1269 Query: 175 YGIMLLELIT-GQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVE 351 +G++L EL+T G + DV D LL+ ++ L+ P E+ + Sbjct: 1270 FGVLLWELMTRGAPPY--------PDVNTFDITVYLLQGRR---LLQP-------EYCPD 1311 Query: 352 ALIQVALLCTQGSPMDRPKMSEVV 423 L +V L C RP SE+V Sbjct: 1312 PLYEVMLKCWHPRAELRPSFSELV 1335
>LCK_MOUSE (P06240) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) Length = 508 Score = 50.8 bits (120), Expect = 2e-06 Identities = 38/145 (26%), Positives = 68/145 (46%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 ANIL+ + + DFGLA+L++ + + I APE ++ G + K+DV+ +G Sbjct: 367 ANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFG 426 Query: 181 IMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEALI 360 I+L E++T R + N + + L+ + +V PD + E L Sbjct: 427 ILLTEIVTHGR-IPYPGMTNPEVIQNLE---------RGYRMVRPD-------NCPEELY 469 Query: 361 QVALLCTQGSPMDRPKMSEVVRMLE 435 + +LC + P DRP + +L+ Sbjct: 470 HLMMLCWKERPEDRPTFDYLRSVLD 494
>KYK1_DICDI (P18160) Non-receptor tyrosine kinase spore lysis A (EC 2.7.10.2)| (Tyrosine-protein kinase 1) Length = 1584 Score = 50.4 bits (119), Expect = 2e-06 Identities = 24/62 (38%), Positives = 41/62 (66%) Frame = +1 Query: 19 EDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGIMLLEL 198 +D + + DFGL++L + + +T +V G I ++APE +SEK+DV+ YG++L EL Sbjct: 1440 QDIKCKISDFGLSRLKKEQASQMTQSV-GCIPYMAPEVFKGDSNSEKSDVYSYGMVLFEL 1498 Query: 199 IT 204 +T Sbjct: 1499 LT 1500
>KRAF1_DROME (P11346) Raf homolog serine/threonine-protein kinase dRAF-1 (EC| 2.7.11.1) (Protein pole-hole) Length = 739 Score = 50.4 bits (119), Expect = 2e-06 Identities = 42/148 (28%), Positives = 70/148 (47%), Gaps = 4/148 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMD-YKDTHVTTAVRGTIGHIAPEYL---STGKSSEKTDVF 171 NI L ED +GDFGLA + G+I +APE + S ++DV+ Sbjct: 553 NIFLHEDLSVKIGDFGLATAKTRWSGEKQANQPTGSILWMAPEVIRMQELNPYSFQSDVY 612 Query: 172 GYGIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVE 351 +GI++ EL+ ++N D ++ + +GLL+ PD+ V + + Sbjct: 613 AFGIVMYELLA--ECLPYGHISNKDQILFMVG-RGLLR---------PDMSQVRSD-APQ 659 Query: 352 ALIQVALLCTQGSPMDRPKMSEVVRMLE 435 AL ++A C + +P DRP ++ MLE Sbjct: 660 ALKRLAEDCIKYTPKDRPLFRPLLNMLE 687
>M3K12_HUMAN (Q12852) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 859 Score = 50.1 bits (118), Expect = 3e-06 Identities = 25/69 (36%), Positives = 42/69 (60%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 N+L+ D + DFG +K + K T ++ A GT+ +APE + SEK D++ +G+ Sbjct: 241 NMLITYDDVVKISDFGTSKELSDKSTKMSFA--GTVAWMAPEVIRNEPVSEKVDIWSFGV 298 Query: 184 MLLELITGQ 210 +L EL+TG+ Sbjct: 299 VLWELLTGE 307
>M3K12_RAT (Q63796) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 50.1 bits (118), Expect = 3e-06 Identities = 25/69 (36%), Positives = 42/69 (60%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 N+L+ D + DFG +K + K T ++ A GT+ +APE + SEK D++ +G+ Sbjct: 274 NMLITYDDVVKISDFGTSKELSDKSTKMSFA--GTVAWMAPEVIRNEPVSEKVDIWSFGV 331 Query: 184 MLLELITGQ 210 +L EL+TG+ Sbjct: 332 VLWELLTGE 340
>M3K12_MOUSE (Q60700) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 50.1 bits (118), Expect = 3e-06 Identities = 25/69 (36%), Positives = 42/69 (60%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 N+L+ D + DFG +K + K T ++ A GT+ +APE + SEK D++ +G+ Sbjct: 274 NMLITYDDVVKISDFGTSKELSDKSTKMSFA--GTVAWMAPEVIRNEPVSEKVDIWSFGV 331 Query: 184 MLLELITGQ 210 +L EL+TG+ Sbjct: 332 VLWELLTGE 340
>HCK_MACFA (Q95M30) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 503 Score = 50.1 bits (118), Expect = 3e-06 Identities = 35/145 (24%), Positives = 68/145 (46%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 ANIL+ + DFGLA++++ + + I APE ++ G S+ K+DV+ +G Sbjct: 362 ANILVSASLVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFGSSTIKSDVWSFG 421 Query: 181 IMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEALI 360 I+L+E++T R ++N + + L+ +G + E+ E L Sbjct: 422 ILLMEIVTYGR-IPYPGMSNPEVIRALE--RGYRMPRP--------------ENCPEELY 464 Query: 361 QVALLCTQGSPMDRPKMSEVVRMLE 435 + + C + P +RP + +L+ Sbjct: 465 NIMMRCWKNRPEERPTFEYIQSVLD 489
>PKNA2_BIFLO (Q8G4G1) Probable serine/threonine-protein kinase pknA2 (EC| 2.7.11.1) Length = 757 Score = 50.1 bits (118), Expect = 3e-06 Identities = 24/73 (32%), Positives = 41/73 (56%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 NIL+++ + DFGLAK T + GT ++APE + +++ + D++ GI Sbjct: 145 NILINDRGHVQITDFGLAKAASQATLSSTGMLLGTAAYLAPEMIENNQATAQGDLYSVGI 204 Query: 184 MLLELITGQRAFD 222 M E++TG+ FD Sbjct: 205 MAWEMLTGKVPFD 217
>PKNB_LACLA (Q9CEF5) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 627 Score = 50.1 bits (118), Expect = 3e-06 Identities = 23/73 (31%), Positives = 41/73 (56%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 N+L+ V DFG+AK + T + G++ +++PE ++ ++D++ GI Sbjct: 141 NVLVSSSGTVKVTDFGIAKALSETSLTQTNTMFGSVHYLSPEQARGSNATVQSDIYAIGI 200 Query: 184 MLLELITGQRAFD 222 +L EL+TGQ FD Sbjct: 201 ILFELLTGQIPFD 213
>MET_PIG (Q2QLE0) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 50.1 bits (118), Expect = 3e-06 Identities = 45/144 (31%), Positives = 68/144 (47%), Gaps = 4/144 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLM---DYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFG 174 N +LDE F V DFGLA+ + +Y H T + + +A E L T K + K+DV+ Sbjct: 1209 NCMLDEKFTVKVADFGLARDVYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWS 1268 Query: 175 YGIMLLELIT-GQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVE 351 +G++L EL+T G + DV D LL+ ++ L+ P E+ + Sbjct: 1269 FGVLLWELMTRGAPPY--------PDVNTFDITVYLLQGRR---LLQP-------EYCPD 1310 Query: 352 ALIQVALLCTQGSPMDRPKMSEVV 423 L +V L C RP SE+V Sbjct: 1311 PLYEVMLKCWHPRAELRPSFSELV 1334
>TESK2_HUMAN (Q96S53) Dual specificity testis-specific protein kinase 2 (EC| 2.7.12.1) (Testicular protein kinase 2) Length = 571 Score = 49.3 bits (116), Expect = 5e-06 Identities = 49/150 (32%), Positives = 65/150 (43%), Gaps = 6/150 (4%) Frame = +1 Query: 4 NILLDED---FEAVVGDFGLA-KLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVF 171 N L+ D + AVV DFGLA K+ D AV G+ +APE L +EK DVF Sbjct: 181 NCLIKRDENGYSAVVADFGLAEKIPDVSMGSEKLAVVGSPFWMAPEVLRDEPYNEKADVF 240 Query: 172 GYGIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVD--PDLQSVYVEHE 345 YGI+L E+I AR+ D D + GL + M+ D PD Sbjct: 241 SYGIILCEII--------ARIQADPDYLPRTENFGLDYDAFQHMVGDCPPD--------- 283 Query: 346 VEALIQVALLCTQGSPMDRPKMSEVVRMLE 435 +Q+ C P RP E+ + LE Sbjct: 284 ---FLQLTFNCCNMDPKLRPSFVEIGKTLE 310
>BRAF1_COTJA (P34908) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (RMIL serine/threonine-protein kinase) (c-RMIL) Length = 807 Score = 49.3 bits (116), Expect = 5e-06 Identities = 41/148 (27%), Positives = 73/148 (49%), Gaps = 4/148 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMD-YKDTHVTTAVRGTIGHIAPEYL---STGKSSEKTDVF 171 NI L ED +GDFGLA + + +H + G+I +APE + S ++DV+ Sbjct: 621 NIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVY 680 Query: 172 GYGIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVE 351 +GI+L EL+TGQ + + + N D ++ + +G L PDL V + + Sbjct: 681 AFGIVLYELMTGQLPY--SNINNRDQIIFMVG-RGYL---------SPDLSKVR-SNCPK 727 Query: 352 ALIQVALLCTQGSPMDRPKMSEVVRMLE 435 A+ ++ C + +RP +++ +E Sbjct: 728 AMKRLMAECLKKKRDERPLFPQILASIE 755
>GPRK1_DROME (P32865) G protein-coupled receptor kinase 1 (EC 2.7.11.16)| Length = 700 Score = 49.3 bits (116), Expect = 5e-06 Identities = 31/74 (41%), Positives = 40/74 (54%), Gaps = 1/74 (1%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEK-TDVFGY 177 ANILLDE+ + D GLA K H + GT G++APE LS G S + D F + Sbjct: 322 ANILLDENGHIRISDLGLACDFSKKKPHASV---GTHGYMAPEVLSKGTSYDSCADWFSF 378 Query: 178 GIMLLELITGQRAF 219 G ML +L+ G F Sbjct: 379 GCMLYKLLKGHSPF 392
>PKN2_CLOPE (Q8XJL8) Probable serine/threonine protein kinase CPE1738 (EC| 2.7.11.1) Length = 685 Score = 49.3 bits (116), Expect = 5e-06 Identities = 26/73 (35%), Positives = 41/73 (56%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 NIL+ E+ V DFG+AK MD T +V G+ + +PE + +TD++ GI Sbjct: 138 NILVTEEGVVKVTDFGIAKSMDSSTIAHTNSVMGSAHYFSPEQAKGTYTDYRTDLYSLGI 197 Query: 184 MLLELITGQRAFD 222 +L E++TG F+ Sbjct: 198 VLYEMVTGVVPFN 210
>BRAF1_HUMAN (P15056) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1) Length = 766 Score = 49.3 bits (116), Expect = 5e-06 Identities = 41/148 (27%), Positives = 73/148 (49%), Gaps = 4/148 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMD-YKDTHVTTAVRGTIGHIAPEYL---STGKSSEKTDVF 171 NI L ED +GDFGLA + + +H + G+I +APE + S ++DV+ Sbjct: 581 NIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVY 640 Query: 172 GYGIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVE 351 +GI+L EL+TGQ + + + N D ++ + +G L PDL V + + Sbjct: 641 AFGIVLYELMTGQLPY--SNINNRDQIIFMVG-RGYL---------SPDLSKVR-SNCPK 687 Query: 352 ALIQVALLCTQGSPMDRPKMSEVVRMLE 435 A+ ++ C + +RP +++ +E Sbjct: 688 AMKRLMAECLKKKRDERPLFPQILASIE 715
>BRAF1_MOUSE (P28028) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Fragment) Length = 328 Score = 49.3 bits (116), Expect = 5e-06 Identities = 41/148 (27%), Positives = 73/148 (49%), Gaps = 4/148 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMD-YKDTHVTTAVRGTIGHIAPEYL---STGKSSEKTDVF 171 NI L ED +GDFGLA + + +H + G+I +APE + S ++DV+ Sbjct: 143 NIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVY 202 Query: 172 GYGIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVE 351 +GI+L EL+TGQ + + + N D ++ + +G L PDL V + + Sbjct: 203 AFGIVLYELMTGQLPY--SNINNRDQIIFMVG-RGYL---------SPDLSKVR-SNCPK 249 Query: 352 ALIQVALLCTQGSPMDRPKMSEVVRMLE 435 A+ ++ C + +RP +++ +E Sbjct: 250 AMKRLMAECLKKKRDERPLFPQILASIE 277
>NEK9_XENLA (Q7ZZC8) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)| (NimA-related protein kinase 9) (XNek9) (Nercc1 kinase) Length = 944 Score = 49.3 bits (116), Expect = 5e-06 Identities = 41/141 (29%), Positives = 65/141 (46%), Gaps = 1/141 (0%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 NI L + +GD+GLAK + + + T V GT+ +++PE K S K+D++ G Sbjct: 163 NIFLTKANLIKLGDYGLAKQLSSEYSMAETCV-GTLYYMSPEICQGVKYSFKSDIWAVGC 221 Query: 184 MLLELITGQRAFDLARLAN-DDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEALI 360 +L EL+T R FD N ++ +W GL +VY + LI Sbjct: 222 VLYELLTLTRTFDATNPLNLCVKIVQGNWAVGL-------------DNTVYTQE----LI 264 Query: 361 QVALLCTQGSPMDRPKMSEVV 423 +V C + P RP E++ Sbjct: 265 EVVHACLEQDPEKRPTADEIL 285
>EPHA3_MOUSE (P29319) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (MEK4) Length = 983 Score = 49.3 bits (116), Expect = 5e-06 Identities = 39/147 (26%), Positives = 76/147 (51%), Gaps = 3/147 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLM--DYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGY 177 NIL++ + V DFGL++++ D + + T + I +PE +S K + +DV+ Y Sbjct: 751 NILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTSPEAMSYRKFTSASDVWSY 810 Query: 178 GIMLLELIT-GQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEA 354 GI+L E+++ G+R + ++++N D + +D ++ + D + A Sbjct: 811 GIVLWEVMSYGERPY--SQMSNQDVIKAVD--------ERYRLPPPMDCPA--------A 852 Query: 355 LIQVALLCTQGSPMDRPKMSEVVRMLE 435 L Q+ L C Q +RPK ++V +L+ Sbjct: 853 LYQLMLDCWQKDRNNRPKFEQIVSILD 879
>RMIL_AVII1 (P10533) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 367 Score = 49.3 bits (116), Expect = 5e-06 Identities = 41/148 (27%), Positives = 73/148 (49%), Gaps = 4/148 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMD-YKDTHVTTAVRGTIGHIAPEYL---STGKSSEKTDVF 171 NI L ED +GDFGLA + + +H + G+I +APE + S ++DV+ Sbjct: 191 NIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVY 250 Query: 172 GYGIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVE 351 +GI+L EL+TGQ + + + N D ++ + +G L PDL V + + Sbjct: 251 AFGIVLYELMTGQLPY--SNINNRDQIIFMVG-RGYL---------SPDLSKVR-SNCPK 297 Query: 352 ALIQVALLCTQGSPMDRPKMSEVVRMLE 435 A+ ++ C + +RP +++ +E Sbjct: 298 AMKRLMAECLKKKRDERPLFPQILASIE 325
>M3K13_PONPY (Q5R8X7) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) Length = 966 Score = 49.3 bits (116), Expect = 5e-06 Identities = 24/69 (34%), Positives = 41/69 (59%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 N+L+ + DFG +K + K T ++ A GT+ +APE + SEK D++ +G+ Sbjct: 284 NVLVTHTDAVKISDFGTSKELSDKSTKMSFA--GTVAWLAPEVIRNEPVSEKVDIWSFGV 341 Query: 184 MLLELITGQ 210 +L EL+TG+ Sbjct: 342 VLWELLTGE 350
>FUSED_DROME (P23647) Serine/threonine-protein kinase fused (EC 2.7.11.1)| Length = 805 Score = 49.3 bits (116), Expect = 5e-06 Identities = 27/72 (37%), Positives = 42/72 (58%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 N+LLD++ A + DFGLA+ M THV T+++GT ++APE L+ D++ G Sbjct: 130 NVLLDKNMHAKLCDFGLARNMTL-GTHVLTSIKGTPLYMAPELLAEQPYDHHADMWSLGC 188 Query: 184 MLLELITGQRAF 219 + E + GQ F Sbjct: 189 IAYESMAGQPPF 200
>RMIL_AVEVR (P27966) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 450 Score = 49.3 bits (116), Expect = 5e-06 Identities = 41/148 (27%), Positives = 73/148 (49%), Gaps = 4/148 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMD-YKDTHVTTAVRGTIGHIAPEYL---STGKSSEKTDVF 171 NI L ED +GDFGLA + + +H + G+I +APE + S ++DV+ Sbjct: 207 NIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVY 266 Query: 172 GYGIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVE 351 +GI+L EL+TGQ + + + N D ++ + +G L PDL V + + Sbjct: 267 AFGIVLYELMTGQLPY--SNINNRDQIIFMVG-RGYL---------SPDLSKVR-SNCPK 313 Query: 352 ALIQVALLCTQGSPMDRPKMSEVVRMLE 435 A+ ++ C + +RP +++ +E Sbjct: 314 AMKRLMAECLKKKRDERPLFPQILASIE 341
>BRAF1_CHICK (Q04982) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Rmil serine/threonine-protein kinase) (c-Rmil) Length = 806 Score = 49.3 bits (116), Expect = 5e-06 Identities = 41/148 (27%), Positives = 73/148 (49%), Gaps = 4/148 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMD-YKDTHVTTAVRGTIGHIAPEYL---STGKSSEKTDVF 171 NI L ED +GDFGLA + + +H + G+I +APE + S ++DV+ Sbjct: 621 NIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVY 680 Query: 172 GYGIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVE 351 +GI+L EL+TGQ + + + N D ++ + +G L PDL V + + Sbjct: 681 AFGIVLYELMTGQLPY--SNINNRDQIIFMVG-RGYL---------SPDLSKVR-SNCPK 727 Query: 352 ALIQVALLCTQGSPMDRPKMSEVVRMLE 435 A+ ++ C + +RP +++ +E Sbjct: 728 AMKRLMAECLKKKRDERPLFPQILASIE 755
>SRK2_SPOLA (P42688) Tyrosine-protein kinase SRK2 (EC 2.7.10.2) (Fragment)| Length = 362 Score = 49.3 bits (116), Expect = 5e-06 Identities = 43/144 (29%), Positives = 66/144 (45%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 NIL+ ++ V DFGLA+L+ D + T + I APE + S K+DV+ +GI Sbjct: 219 NILVGDNNICKVADFGLARLIVSDDYNATEGAKFPIKWTAPEAALFNRFSIKSDVWSFGI 278 Query: 184 MLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEALIQ 363 ++ EL+T R ++N + + LD KG V E+L Q Sbjct: 279 LITELVTYGR-IPYPGMSNAEVLQNLD--KGYRMPCPVT--------------TPESLYQ 321 Query: 364 VALLCTQGSPMDRPKMSEVVRMLE 435 + L C + +P DRP + LE Sbjct: 322 IMLDCWKRNPADRPTFEALQWRLE 345
>SRC_AVIST (P14085) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 556 Score = 48.9 bits (115), Expect = 7e-06 Identities = 44/157 (28%), Positives = 68/157 (43%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 ANIL+ E+ V DFGLA+L++ + + I APE G+ + K+DV+ +G Sbjct: 389 ANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFG 448 Query: 181 IMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEALI 360 I+L EL T R + N + +LD V E+ M P+ E+L Sbjct: 449 ILLTELTTKGRV-PYPGMVNRE---VLDQV-----ERGYRMPCPPECP--------ESLH 491 Query: 361 QVALLCTQGSPMDRPKMSEVVRMLEGDGLAERWEEWQ 471 + C + P +RP + LE W W+ Sbjct: 492 DLMCQCWRKDPEERPTFEYLQAFLEDYLGILAWTPWE 528
>YP150_YEAST (Q12152) Putative serine/threonine-protein kinase YPL150W (EC| 2.7.11.1) Length = 901 Score = 48.9 bits (115), Expect = 7e-06 Identities = 47/142 (33%), Positives = 67/142 (47%), Gaps = 1/142 (0%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGK-SSEKTDVFGYG 180 NILLD++ A + DFG + K T T V GT ++APE + K D++ G Sbjct: 162 NILLDKNGNAKLTDFGFTRECMTKTTLET--VCGTTVYMAPELIERRTYDGFKIDIWSLG 219 Query: 181 IMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEALI 360 ++L LITG FD DDD W K + +E K + V PD + LI Sbjct: 220 VILYTLITGYLPFD------DDDEAKTKW-KIVNEEPKYDAKVIPD--------DARDLI 264 Query: 361 QVALLCTQGSPMDRPKMSEVVR 426 L +P +RP +S+V+R Sbjct: 265 SRLL---AKNPGERPSLSQVLR 283
>IRAK3_MOUSE (Q8K4B2) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 609 Score = 48.9 bits (115), Expect = 7e-06 Identities = 39/158 (24%), Positives = 73/158 (46%), Gaps = 13/158 (8%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKL-----MDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTD 165 ANILLD+ + + DF A ++T R + ++ EY+ G+ S KTD Sbjct: 310 ANILLDDQLQPKLTDFAAAHFRPNLEQQSSTINMTGGGRKHLWYMPEEYIRQGRLSVKTD 369 Query: 166 VFGYGIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHE 345 V+ +GI+++E++TG + L + V L D + L++++ ++ + +++ + Sbjct: 370 VYSFGIVIMEVLTGCKVV----LDDPKHVQLRDLLMELMEKRGLDSCLS------FLDRK 419 Query: 346 V--------EALIQVALLCTQGSPMDRPKMSEVVRMLE 435 + L +A C RP M EV+ LE Sbjct: 420 IPPCPRNFSAKLFSLAGRCVATKAKLRPTMDEVLSSLE 457
>SRC2_XENLA (P13116) Tyrosine-protein kinase Src-2 (EC 2.7.10.2) (p60-Src-2)| Length = 531 Score = 48.9 bits (115), Expect = 7e-06 Identities = 43/145 (29%), Positives = 65/145 (44%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 ANIL+ E+ V DFGLA+L++ + + I APE G+ + K+DV+ +G Sbjct: 388 ANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFG 447 Query: 181 IMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEALI 360 I+L EL T R + N + +LD V E+ M PD E+L Sbjct: 448 ILLTELTTKGRV-PYPGMVNRE---VLDQV-----ERGYRMPCPPDCP--------ESLH 490 Query: 361 QVALLCTQGSPMDRPKMSEVVRMLE 435 + C + P +RP + LE Sbjct: 491 DLMFQCWRKDPEERPTFEYLQAFLE 515
>SRC1_XENLA (P13115) Tyrosine-protein kinase Src-1 (EC 2.7.10.2) (p60-Src-1)| Length = 531 Score = 48.9 bits (115), Expect = 7e-06 Identities = 43/145 (29%), Positives = 65/145 (44%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 ANIL+ E+ V DFGLA+L++ + + I APE G+ + K+DV+ +G Sbjct: 388 ANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFG 447 Query: 181 IMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEALI 360 I+L EL T R + N + +LD V E+ M PD E+L Sbjct: 448 ILLTELTTKGRV-PYPGMVNRE---VLDQV-----ERGYRMPCPPDCP--------ESLH 490 Query: 361 QVALLCTQGSPMDRPKMSEVVRMLE 435 + C + P +RP + LE Sbjct: 491 DLMFQCWRKDPEERPTFEYLQAFLE 515
>M3K13_HUMAN (O43283) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase) Length = 966 Score = 48.9 bits (115), Expect = 7e-06 Identities = 24/69 (34%), Positives = 41/69 (59%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 N+L+ + DFG +K + K T ++ A GT+ +APE + SEK D++ +G+ Sbjct: 284 NVLVTHTDAVKISDFGTSKELSDKSTKMSFA--GTVAWMAPEVIRNEPVSEKVDIWSFGV 341 Query: 184 MLLELITGQ 210 +L EL+TG+ Sbjct: 342 VLWELLTGE 350
>YRK_CHICK (Q02977) Proto-oncogene tyrosine-protein kinase Yrk (EC 2.7.10.2)| (p60-Yrk) (Yes-related kinase) Length = 535 Score = 48.5 bits (114), Expect = 9e-06 Identities = 26/71 (36%), Positives = 41/71 (57%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 ANIL+ ++ + DFGLA+L++ + + I APE GK + K+DV+ +G Sbjct: 392 ANILVGDNLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALFGKFTIKSDVWSFG 451 Query: 181 IMLLELITGQR 213 I+L EL+T R Sbjct: 452 ILLTELVTKGR 462
>NEK8_MOUSE (Q91ZR4) Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never| in mitosis A-related kinase 8) (NimA-related protein kinase 8) Length = 698 Score = 48.5 bits (114), Expect = 9e-06 Identities = 30/78 (38%), Positives = 47/78 (60%), Gaps = 1/78 (1%) Frame = +1 Query: 4 NILLDEDFEAV-VGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 NILLD+ V +GDFG++K++ K T V GT +I+PE ++K+D++ G Sbjct: 133 NILLDKHRMVVKIGDFGISKILSSKSKAYT--VVGTPCYISPELCEGKPYNQKSDIWALG 190 Query: 181 IMLLELITGQRAFDLARL 234 +L EL + +RAF+ A L Sbjct: 191 CVLYELASLKRAFEAANL 208
>NEK8_HUMAN (Q86SG6) Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never| in mitosis A-related kinase 8) (NimA-related protein kinase 8) (NIMA-related kinase 12a) Length = 692 Score = 48.5 bits (114), Expect = 9e-06 Identities = 30/78 (38%), Positives = 47/78 (60%), Gaps = 1/78 (1%) Frame = +1 Query: 4 NILLDEDFEAV-VGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 NILLD+ V +GDFG++K++ K T V GT +I+PE ++K+D++ G Sbjct: 133 NILLDKHRMVVKIGDFGISKILSSKSKAYT--VVGTPCYISPELCEGKPYNQKSDIWALG 190 Query: 181 IMLLELITGQRAFDLARL 234 +L EL + +RAF+ A L Sbjct: 191 CVLYELASLKRAFEAANL 208
>EPHA4_MOUSE (Q03137) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK) (MPK-3) Length = 986 Score = 48.5 bits (114), Expect = 9e-06 Identities = 39/147 (26%), Positives = 74/147 (50%), Gaps = 3/147 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLM--DYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGY 177 NIL++ + V DFG+++++ D + + T + I APE ++ K + +DV+ Y Sbjct: 751 NILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSY 810 Query: 178 GIMLLELIT-GQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEA 354 GI++ E+++ G+R + D+ D +K + + ++ +D + A Sbjct: 811 GIVMWEVMSYGERPYW--------DMSNQDVIKAIEEGYRLPPPMDCPI----------A 852 Query: 355 LIQVALLCTQGSPMDRPKMSEVVRMLE 435 L Q+ L C Q DRPK ++V ML+ Sbjct: 853 LHQLMLDCWQKERSDRPKFGQIVNMLD 879
>EPHA4_HUMAN (P54764) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8) Length = 986 Score = 48.5 bits (114), Expect = 9e-06 Identities = 39/147 (26%), Positives = 74/147 (50%), Gaps = 3/147 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLM--DYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGY 177 NIL++ + V DFG+++++ D + + T + I APE ++ K + +DV+ Y Sbjct: 751 NILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSY 810 Query: 178 GIMLLELIT-GQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEA 354 GI++ E+++ G+R + D+ D +K + + ++ +D + A Sbjct: 811 GIVMWEVMSYGERPYW--------DMSNQDVIKAIEEGYRLPPPMDCPI----------A 852 Query: 355 LIQVALLCTQGSPMDRPKMSEVVRMLE 435 L Q+ L C Q DRPK ++V ML+ Sbjct: 853 LHQLMLDCWQKERSDRPKFGQIVNMLD 879
>EPHA4_CHICK (Q07496) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK8) Length = 986 Score = 48.5 bits (114), Expect = 9e-06 Identities = 39/147 (26%), Positives = 74/147 (50%), Gaps = 3/147 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLM--DYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGY 177 NIL++ + V DFG+++++ D + + T + I APE ++ K + +DV+ Y Sbjct: 751 NILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSY 810 Query: 178 GIMLLELIT-GQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEA 354 GI++ E+++ G+R + D+ D +K + + ++ +D + A Sbjct: 811 GIVMWEVMSYGERPYW--------DMSNQDVIKAIEEGYRLPPPMDCPI----------A 852 Query: 355 LIQVALLCTQGSPMDRPKMSEVVRMLE 435 L Q+ L C Q DRPK ++V ML+ Sbjct: 853 LHQLMLDCWQKERSDRPKFGQIVNMLD 879
>TESK2_RAT (Q924U5) Dual specificity testis-specific protein kinase 2 (EC| 2.7.12.1) (Testicular protein kinase 2) Length = 570 Score = 48.5 bits (114), Expect = 9e-06 Identities = 46/148 (31%), Positives = 62/148 (41%), Gaps = 4/148 (2%) Frame = +1 Query: 4 NILLDED---FEAVVGDFGLA-KLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVF 171 N L+ D + AVV DFGLA K+ D AV G+ +APE L +EK DVF Sbjct: 181 NCLIKRDENGYSAVVADFGLAEKIPDASIGSEKLAVVGSPFWMAPEVLRDEPYNEKADVF 240 Query: 172 GYGIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVE 351 YGI+L E+I AR+ D D + + +D D V Sbjct: 241 SYGIILCEII--------ARIQADPDYL----------PRTENFGLDYDAFQHMVGDCPS 282 Query: 352 ALIQVALLCTQGSPMDRPKMSEVVRMLE 435 +Q+ C P RP E+ + LE Sbjct: 283 DFLQLTFNCCNMDPKLRPSFEEIGKTLE 310
>TNI3K_RAT (Q7TQP6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 834 Score = 48.5 bits (114), Expect = 9e-06 Identities = 29/73 (39%), Positives = 40/73 (54%), Gaps = 1/73 (1%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPE-YLSTGKSSEKTDVFGYG 180 NILL ED AVV DFG ++ + D T G + +APE + + + K DVF Y Sbjct: 592 NILLYEDGHAVVADFGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYS 651 Query: 181 IMLLELITGQRAF 219 + L EL+TG+ F Sbjct: 652 LCLWELLTGEIPF 664
>SRC_RSVPA (P31693) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 522 Score = 48.1 bits (113), Expect = 1e-05 Identities = 27/71 (38%), Positives = 40/71 (56%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 ANIL+ E+ V DFGLA+L++ + R + APE G+ + K+DV+ +G Sbjct: 386 ANILVGENLVCKVADFGLARLIEDNEYTARPGARFPVKWTAPEAALYGRFTIKSDVWSFG 445 Query: 181 IMLLELITGQR 213 I+L EL T R Sbjct: 446 ILLTELTTKGR 456
>EPA4B_XENLA (Q91694) Ephrin type-A receptor 4-B precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor PAG) (Pagliaccio) Length = 985 Score = 48.1 bits (113), Expect = 1e-05 Identities = 39/147 (26%), Positives = 74/147 (50%), Gaps = 3/147 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLM--DYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGY 177 NIL++ + V DFG+++++ D + + T + I APE ++ K + +DV+ Y Sbjct: 750 NILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSY 809 Query: 178 GIMLLELIT-GQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEA 354 GI++ E+++ G+R + D+ D +K + + ++ +D + A Sbjct: 810 GIVMWEVMSYGERPYW--------DMSNQDVIKAIEEGYRLPPPMDCPI----------A 851 Query: 355 LIQVALLCTQGSPMDRPKMSEVVRMLE 435 L Q+ L C Q DRPK ++V ML+ Sbjct: 852 LHQLMLDCWQKDRSDRPKFGQIVSMLD 878
>JIL1_DROME (Q9V3I5) Chromosomal serine/threonine-protein kinase JIL-1 (EC| 2.7.11.1) Length = 1207 Score = 48.1 bits (113), Expect = 1e-05 Identities = 25/74 (33%), Positives = 43/74 (58%), Gaps = 2/74 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKT--DVFGY 177 NILLD + V+ DFGL+K++ ++ + + GT+ ++APE + TG + D + Sbjct: 394 NILLDGEGHIVLSDFGLSKILTAENEYRAHSFCGTLEYMAPEIIRTGPPGHDSAVDWWSV 453 Query: 178 GIMLLELITGQRAF 219 G++ EL+TG F Sbjct: 454 GVLTFELLTGASPF 467 Score = 32.7 bits (73), Expect = 0.53 Identities = 39/150 (26%), Positives = 62/150 (41%), Gaps = 10/150 (6%) Frame = +1 Query: 4 NILLD--EDFEAVVGDFGLA----KLMDYKDTHVTTAVRGTIGHIAPEYLSTGKS---SE 156 NI+ + ED + DFG A + +KD R T+ + PE L+ S Sbjct: 744 NIMFENREDRTVKLIDFGSACYNNRFKSWKDKP-----RYTLDYAPPEMLADANLVTYSP 798 Query: 157 KTDVFGYGIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDP-DLQSVY 333 D++G G L ++ G R + N+DDV D E + M + +S+ Sbjct: 799 AVDIYGLGATLYTMLVGHRPYR----QNEDDV---DHSAAAHHELRKRMRRGTFNQRSMR 851 Query: 334 VEHEVEALIQVALLCTQGSPMDRPKMSEVV 423 E A + C Q P DRP +S+++ Sbjct: 852 WESASPAFRHLVSWCLQRDPADRPTLSDIL 881
>EPA4A_XENLA (Q91845) Ephrin type-A receptor 4-A precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK-1) (xSEK-1) Length = 986 Score = 48.1 bits (113), Expect = 1e-05 Identities = 39/147 (26%), Positives = 74/147 (50%), Gaps = 3/147 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLM--DYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGY 177 NIL++ + V DFG+++++ D + + T + I APE ++ K + +DV+ Y Sbjct: 750 NILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSY 809 Query: 178 GIMLLELIT-GQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEA 354 GI++ E+++ G+R + D+ D +K + + ++ +D + A Sbjct: 810 GIVMWEVMSYGERPYW--------DMSNQDVIKAIEEGYRLPPPMDCPI----------A 851 Query: 355 LIQVALLCTQGSPMDRPKMSEVVRMLE 435 L Q+ L C Q DRPK ++V ML+ Sbjct: 852 LHQLMLDCWQKERSDRPKFGQIVSMLD 878
>SPKA_SYNY3 (Q9FAB3) Serine/threonine-protein kinase A (EC 2.7.11.1)| Length = 521 Score = 48.1 bits (113), Expect = 1e-05 Identities = 25/74 (33%), Positives = 45/74 (60%), Gaps = 4/74 (5%) Frame = +1 Query: 1 ANILLDED---FEAV-VGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDV 168 +N+LL ED E V + DFG+AKL+ + T A GT+ + +PE + + ++D+ Sbjct: 152 SNVLLVEDPALGELVKILDFGIAKLVQAAEESKTQAFMGTLAYCSPEQMEGKELDSRSDI 211 Query: 169 FGYGIMLLELITGQ 210 + G+M+ E++TG+ Sbjct: 212 YSLGVMMYEMLTGE 225
>KPC4_DROME (P83099) Putative protein kinase C, delta type homolog (EC| 2.7.11.13) Length = 643 Score = 48.1 bits (113), Expect = 1e-05 Identities = 24/72 (33%), Positives = 40/72 (55%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 N+LLD + + DFG+ KL Y D + GT ++APE + K ++ D + +G+ Sbjct: 444 NVLLDYEGHVRIADFGMCKLQIYLDK-TADSFCGTPDYMAPEIIKGEKYNQNVDWWSFGV 502 Query: 184 MLLELITGQRAF 219 +L E++ GQ F Sbjct: 503 LLYEMLIGQSPF 514
>TNI3K_HUMAN (Q59H18) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 936 Score = 47.8 bits (112), Expect = 2e-05 Identities = 28/73 (38%), Positives = 40/73 (54%), Gaps = 1/73 (1%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPE-YLSTGKSSEKTDVFGYG 180 NILL ED AVV DFG ++ + D T G + +APE + + + K DVF Y Sbjct: 694 NILLYEDGHAVVADFGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYA 753 Query: 181 IMLLELITGQRAF 219 + L E++TG+ F Sbjct: 754 LCLWEILTGEIPF 766
>ABL1_MOUSE (P00520) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1123 Score = 47.8 bits (112), Expect = 2e-05 Identities = 39/145 (26%), Positives = 64/145 (44%), Gaps = 1/145 (0%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 N L+ E+ V DFGL++LM + I APE L+ K S K+DV+ +G+ Sbjct: 368 NCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGV 427 Query: 184 MLLELIT-GQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEALI 360 +L E+ T G + L+ +V L++ D + E E + Sbjct: 428 LLWEIATYGMSPYPGIDLS------------------QVYELLEKDYRMERPEGCPEKVY 469 Query: 361 QVALLCTQGSPMDRPKMSEVVRMLE 435 ++ C Q +P DRP +E+ + E Sbjct: 470 ELMRACWQWNPSDRPSFAEIHQAFE 494
>EPHA5_HUMAN (P54756) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein-tyrosine kinase HEK7) Length = 1037 Score = 47.8 bits (112), Expect = 2e-05 Identities = 40/147 (27%), Positives = 71/147 (48%), Gaps = 3/147 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLM--DYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGY 177 NIL++ + V DFGL++++ D + + T + I APE ++ K + +DV+ Y Sbjct: 805 NILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSY 864 Query: 178 GIMLLELIT-GQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEA 354 GI++ E+++ G+R + + N D + + E+ + D + A Sbjct: 865 GIVMWEVVSYGERPY--WEMTNQDVIKAV--------EEGYRLPSPMDCPA--------A 906 Query: 355 LIQVALLCTQGSPMDRPKMSEVVRMLE 435 L Q+ L C Q RPK E+V ML+ Sbjct: 907 LYQLMLDCWQKERNSRPKFDEIVNMLD 933
>FGR_MOUSE (P14234) Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2)| (P55-FGR) (C-FGR) Length = 517 Score = 47.8 bits (112), Expect = 2e-05 Identities = 27/71 (38%), Positives = 41/71 (57%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 ANIL+ E + DFGLA+L++ + + + I APE G+ + K+DV+ +G Sbjct: 374 ANILVGEYLICKIADFGLARLIEDNEYNPQQGTKFPIKWTAPEAALFGRFTVKSDVWSFG 433 Query: 181 IMLLELITGQR 213 I+L ELIT R Sbjct: 434 ILLTELITKGR 444
>ABL1_HUMAN (P00519) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1130 Score = 47.8 bits (112), Expect = 2e-05 Identities = 39/145 (26%), Positives = 64/145 (44%), Gaps = 1/145 (0%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 N L+ E+ V DFGL++LM + I APE L+ K S K+DV+ +G+ Sbjct: 368 NCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGV 427 Query: 184 MLLELIT-GQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEALI 360 +L E+ T G + L+ +V L++ D + E E + Sbjct: 428 LLWEIATYGMSPYPGIDLS------------------QVYELLEKDYRMERPEGCPEKVY 469 Query: 361 QVALLCTQGSPMDRPKMSEVVRMLE 435 ++ C Q +P DRP +E+ + E Sbjct: 470 ELMRACWQWNPSDRPSFAEIHQAFE 494
>KPCT_HUMAN (Q04759) Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)| Length = 706 Score = 47.8 bits (112), Expect = 2e-05 Identities = 33/108 (30%), Positives = 51/108 (47%), Gaps = 6/108 (5%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 NILLD+D + DFG+ K D T GT +IAPE L K + D + +G+ Sbjct: 509 NILLDKDGHIKIADFGMCKENMLGDAKTNTFC-GTPDYIAPEILLGQKYNHSVDWWSFGV 567 Query: 184 MLLELITGQRAF------DLARLANDDDVMLLDWVKGLLKEKKVEMLV 309 +L E++ GQ F +L D+ W++ K+ V++ V Sbjct: 568 LLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWLEKEAKDLLVKLFV 615
>JAK3_HUMAN (P52333) Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3)| (JAK-3) (Leukocyte janus kinase) (L-JAK) Length = 1124 Score = 47.8 bits (112), Expect = 2e-05 Identities = 48/152 (31%), Positives = 72/152 (47%), Gaps = 8/152 (5%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDY-KDTHVTTAV-RGTIGHIAPEYLSTGKSSEKTDVFGY 177 NIL++ + + DFGLAKL+ KD +V + I APE LS S ++DV+ + Sbjct: 954 NILVESEAHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSF 1013 Query: 178 GIMLLELIT------GQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVE 339 G++L EL T A L + + DV L + LL+E + + P + Sbjct: 1014 GVVLYELFTYCDKSCSPSAEFLRMMGCERDVPALCRLLELLEEGQ-RLPAPPACPA---- 1068 Query: 340 HEVEALIQVALLCTQGSPMDRPKMSEVVRMLE 435 EV L++ LC SP DRP S + L+ Sbjct: 1069 -EVHELMK---LCWAPSPQDRPSFSALGPQLD 1096
>M3LK7_DROME (P83104) Putative mitogen-activated protein kinase kinase kinase| 7-like (EC 2.7.11.25) Length = 393 Score = 47.8 bits (112), Expect = 2e-05 Identities = 41/143 (28%), Positives = 69/143 (48%), Gaps = 1/143 (0%) Frame = +1 Query: 7 ILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGIM 186 +L ++ + + DFGLA M T + +GT+ ++APE + K + K DV+ +GIM Sbjct: 140 LLYNQHEDLKICDFGLATDMSNNKTDM----QGTLRYMAPEAIKHLKYTAKCDVYSFGIM 195 Query: 187 LLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEM-LVDPDLQSVYVEHEVEALIQ 363 L EL+T Q + + L N + + +K + +K+ M V D E + Q Sbjct: 196 LWELMTRQLPY--SHLENPNSQYAI--MKAISSGEKLPMEAVRSDCP--------EGIKQ 243 Query: 364 VALLCTQGSPMDRPKMSEVVRML 432 + C +P RP M E+ + L Sbjct: 244 LMECCMDINPEKRPSMKEIEKFL 266
>PKAA_STRCO (P54739) Serine/threonine protein kinase pkaA (EC 2.7.11.1)| Length = 543 Score = 47.8 bits (112), Expect = 2e-05 Identities = 27/76 (35%), Positives = 41/76 (53%), Gaps = 3/76 (3%) Frame = +1 Query: 1 ANILLDE---DFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVF 171 AN+LL + + ++ DFG+A+L D T GT ++APE + DV+ Sbjct: 146 ANVLLKQTGGEMHPMLTDFGIARLADSPGLTRTHEFVGTPAYVAPESAEGRPQTSAVDVY 205 Query: 172 GYGIMLLELITGQRAF 219 G GI+L EL+TG+ F Sbjct: 206 GAGILLYELVTGRPPF 221
>ABL_MLVAB (P00521) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 746 Score = 47.8 bits (112), Expect = 2e-05 Identities = 39/145 (26%), Positives = 64/145 (44%), Gaps = 1/145 (0%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 N L+ E+ V DFGL++LM + I APE L+ K S K+DV+ +G+ Sbjct: 254 NCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGV 313 Query: 184 MLLELIT-GQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEALI 360 +L E+ T G + L+ +V L++ D + E E + Sbjct: 314 LLWEIATYGMSPYPGIDLS------------------QVYELLEKDYRMERPEGCPEKVY 355 Query: 361 QVALLCTQGSPMDRPKMSEVVRMLE 435 ++ C Q +P DRP +E+ + E Sbjct: 356 ELMRACWQWNPSDRPSFAEIHQAFE 380
>EPHA5_MOUSE (Q60629) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7) Length = 877 Score = 47.8 bits (112), Expect = 2e-05 Identities = 40/147 (27%), Positives = 71/147 (48%), Gaps = 3/147 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLM--DYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGY 177 NIL++ + V DFGL++++ D + + T + I APE ++ K + +DV+ Y Sbjct: 644 NILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSY 703 Query: 178 GIMLLELIT-GQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEA 354 GI++ E+++ G+R + + N D + + E+ + D + A Sbjct: 704 GIVMWEVVSYGERPY--WEMTNQDVIKAV--------EEGYRLPSPMDCPA--------A 745 Query: 355 LIQVALLCTQGSPMDRPKMSEVVRMLE 435 L Q+ L C Q RPK E+V ML+ Sbjct: 746 LYQLMLDCWQKDRNSRPKFDEIVNMLD 772
>SRC_CHICK (P00523) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 532 Score = 47.4 bits (111), Expect = 2e-05 Identities = 27/71 (38%), Positives = 40/71 (56%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 ANIL+ E+ V DFGLA+L++ + + I APE G+ + K+DV+ +G Sbjct: 389 ANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFG 448 Query: 181 IMLLELITGQR 213 I+L EL T R Sbjct: 449 ILLTELTTKGR 459
>SRC_RSVSE (P63185) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 47.4 bits (111), Expect = 2e-05 Identities = 27/71 (38%), Positives = 40/71 (56%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 ANIL+ E+ V DFGLA+L++ + + I APE G+ + K+DV+ +G Sbjct: 389 ANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFG 448 Query: 181 IMLLELITGQR 213 I+L EL T R Sbjct: 449 ILLTELTTKGR 459
>SRC_RSVSA (P00524) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 47.4 bits (111), Expect = 2e-05 Identities = 27/71 (38%), Positives = 40/71 (56%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 ANIL+ E+ V DFGLA+L++ + + I APE G+ + K+DV+ +G Sbjct: 389 ANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFG 448 Query: 181 IMLLELITGQR 213 I+L EL T R Sbjct: 449 ILLTELTTKGR 459
>SRC_RSVP (P00526) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 47.4 bits (111), Expect = 2e-05 Identities = 27/71 (38%), Positives = 40/71 (56%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 ANIL+ E+ V DFGLA+L++ + + I APE G+ + K+DV+ +G Sbjct: 389 ANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFG 448 Query: 181 IMLLELITGQR 213 I+L EL T R Sbjct: 449 ILLTELTTKGR 459
>SRC_RSVH1 (P25020) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 47.4 bits (111), Expect = 2e-05 Identities = 27/71 (38%), Positives = 40/71 (56%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 ANIL+ E+ V DFGLA+L++ + + I APE G+ + K+DV+ +G Sbjct: 389 ANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFG 448 Query: 181 IMLLELITGQR 213 I+L EL T R Sbjct: 449 ILLTELTTKGR 459
>SRC_AVISR (P00525) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 47.4 bits (111), Expect = 2e-05 Identities = 27/71 (38%), Positives = 40/71 (56%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 ANIL+ E+ V DFGLA+L++ + + I APE G+ + K+DV+ +G Sbjct: 389 ANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFG 448 Query: 181 IMLLELITGQR 213 I+L EL T R Sbjct: 449 ILLTELTTKGR 459
>HCK_HUMAN (P08631) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p59-HCK/p60-HCK) (Hemopoietic cell kinase) Length = 525 Score = 47.4 bits (111), Expect = 2e-05 Identities = 34/145 (23%), Positives = 67/145 (46%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 ANIL+ + DFGLA++++ + + I APE ++ G + K+DV+ +G Sbjct: 384 ANILVSASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFG 443 Query: 181 IMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEALI 360 I+L+E++T R ++N + + L+ +G + E+ E L Sbjct: 444 ILLMEIVTYGR-IPYPGMSNPEVIRALE--RGYRMPRP--------------ENCPEELY 486 Query: 361 QVALLCTQGSPMDRPKMSEVVRMLE 435 + + C + P +RP + +L+ Sbjct: 487 NIMMRCWKNRPEERPTFEYIQSVLD 511
>SRC_AVIS2 (P15054) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 586 Score = 47.4 bits (111), Expect = 2e-05 Identities = 27/71 (38%), Positives = 40/71 (56%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 ANIL+ E+ V DFGLA+L++ + + I APE G+ + K+DV+ +G Sbjct: 389 ANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFG 448 Query: 181 IMLLELITGQR 213 I+L EL T R Sbjct: 449 ILLTELTTKGR 459
>SRC_RAT (Q9WUD9) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 535 Score = 47.4 bits (111), Expect = 2e-05 Identities = 27/71 (38%), Positives = 40/71 (56%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 ANIL+ E+ V DFGLA+L++ + + I APE G+ + K+DV+ +G Sbjct: 392 ANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFG 451 Query: 181 IMLLELITGQR 213 I+L EL T R Sbjct: 452 ILLTELTTKGR 462
>SRC_HUMAN (P12931) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 535 Score = 47.4 bits (111), Expect = 2e-05 Identities = 27/71 (38%), Positives = 40/71 (56%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 ANIL+ E+ V DFGLA+L++ + + I APE G+ + K+DV+ +G Sbjct: 392 ANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFG 451 Query: 181 IMLLELITGQR 213 I+L EL T R Sbjct: 452 ILLTELTTKGR 462
>LCK_SAISC (Q95KR7) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 47.4 bits (111), Expect = 2e-05 Identities = 23/71 (32%), Positives = 41/71 (57%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 ANIL+ + + DFGLA+L++ + + I APE ++ G + K+DV+ +G Sbjct: 367 ANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFG 426 Query: 181 IMLLELITGQR 213 I++ E++T R Sbjct: 427 ILMTEIVTHGR 437
>SRC_AVISS (P14084) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 567 Score = 47.4 bits (111), Expect = 2e-05 Identities = 27/71 (38%), Positives = 40/71 (56%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 ANIL+ E+ V DFGLA+L++ + + I APE G+ + K+DV+ +G Sbjct: 389 ANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFG 448 Query: 181 IMLLELITGQR 213 I+L EL T R Sbjct: 449 ILLTELTTKGR 459
>FIN1_SCHPO (O13839) G2-specific protein kinase fin1 (EC 2.7.11.1)| Length = 722 Score = 47.4 bits (111), Expect = 2e-05 Identities = 27/67 (40%), Positives = 43/67 (64%), Gaps = 1/67 (1%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHV-TTAVRGTIGHIAPEYLSTGKSSEKTDVFGY 177 ANI LDE+ +GDFGL+KL+D +T V T + GT +++PE + + S K+DV+ Sbjct: 155 ANIFLDENNSVKLGDFGLSKLLD--NTRVFTQSYVGTPYYMSPEIIRSSPYSAKSDVWAL 212 Query: 178 GIMLLEL 198 G ++ E+ Sbjct: 213 GCVIFEI 219
>YES_AVISY (P00527) Tyrosine-protein kinase transforming protein YES (EC| 2.7.10.2) (Fragment) Length = 528 Score = 47.4 bits (111), Expect = 2e-05 Identities = 25/71 (35%), Positives = 41/71 (57%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 ANIL+ ++ + DFGLA+L++ + + I APE G+ + K+DV+ +G Sbjct: 390 ANILVGDNLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFG 449 Query: 181 IMLLELITGQR 213 I+L EL+T R Sbjct: 450 ILLTELVTKGR 460
>YES_CHICK (P09324) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 540 Score = 47.4 bits (111), Expect = 2e-05 Identities = 25/71 (35%), Positives = 41/71 (57%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 ANIL+ ++ + DFGLA+L++ + + I APE G+ + K+DV+ +G Sbjct: 397 ANILVGDNLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFG 456 Query: 181 IMLLELITGQR 213 I+L EL+T R Sbjct: 457 ILLTELVTKGR 467
>SRC_MOUSE (P05480) Neuronal proto-oncogene tyrosine-protein kinase Src (EC| 2.7.10.2) (p60-Src) (c-Src) (pp60c-src) Length = 540 Score = 47.4 bits (111), Expect = 2e-05 Identities = 27/71 (38%), Positives = 40/71 (56%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 ANIL+ E+ V DFGLA+L++ + + I APE G+ + K+DV+ +G Sbjct: 397 ANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFG 456 Query: 181 IMLLELITGQR 213 I+L EL T R Sbjct: 457 ILLTELTTKGR 467
>FYN_XIPHE (P27446) Proto-oncogene tyrosine-protein kinase FYN (EC 2.7.10.2)| (P59-FYN) Length = 536 Score = 47.4 bits (111), Expect = 2e-05 Identities = 25/71 (35%), Positives = 41/71 (57%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 ANIL+ ++ + DFGLA+L++ + + I APE G+ + K+DV+ +G Sbjct: 393 ANILVGDNLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFG 452 Query: 181 IMLLELITGQR 213 I+L EL+T R Sbjct: 453 ILLTELVTKGR 463
>TESK2_MOUSE (Q8VCT9) Dual specificity testis-specific protein kinase 2 (EC| 2.7.12.1) (Testicular protein kinase 2) Length = 570 Score = 47.4 bits (111), Expect = 2e-05 Identities = 45/148 (30%), Positives = 62/148 (41%), Gaps = 4/148 (2%) Frame = +1 Query: 4 NILLDED---FEAVVGDFGLA-KLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVF 171 N L+ D + AVV DFGLA K+ D AV G+ +APE L +EK DVF Sbjct: 181 NCLIKRDENGYSAVVADFGLAEKIPDASIGREKLAVVGSPFWMAPEVLRDEPYNEKADVF 240 Query: 172 GYGIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVE 351 YGI+L E+I AR+ D D + + +D D V Sbjct: 241 SYGIILCEII--------ARIQADPDYL----------PRTENFGLDYDAFQNMVGDCPS 282 Query: 352 ALIQVALLCTQGSPMDRPKMSEVVRMLE 435 +Q+ C P RP E+ + L+ Sbjct: 283 DFLQLTFNCCNMDPKLRPSFEEIGKTLK 310
>KPC3_CAEEL (Q19266) Protein kinase C-like 3 (EC 2.7.11.13) (Atypical protein| kinase C-3) (aPKC3) Length = 597 Score = 47.4 bits (111), Expect = 2e-05 Identities = 23/82 (28%), Positives = 45/82 (54%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 N+L+D + + D+G+ K + KD +T+ GT +IAPE L + D + G+ Sbjct: 382 NVLIDAEGHIKLTDYGMCK-ENIKDGDLTSTFCGTPNYIAPEILRGDEYGFSVDWWALGV 440 Query: 184 MLLELITGQRAFDLARLANDDD 249 ++ E++ G+ FD+ + N ++ Sbjct: 441 LMFEMMAGRSPFDIVGMQNSEE 462
>EPHA2_MOUSE (Q03145) Ephrin type-A receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2) Length = 977 Score = 47.4 bits (111), Expect = 2e-05 Identities = 38/147 (25%), Positives = 71/147 (48%), Gaps = 3/147 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLM--DYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGY 177 NIL++ + V DFGL++++ D + T+ T+ + I APE +S K + +DV+ Y Sbjct: 745 NILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGGKIPIRWTAPEAISYRKFTSASDVWSY 804 Query: 178 GIMLLELIT-GQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEA 354 GI++ E++T G+R + W L +V ++ + A Sbjct: 805 GIVMWEVMTYGERPY---------------WE---LSNHEVMKAINDGFRLPTPMDCPSA 846 Query: 355 LIQVALLCTQGSPMDRPKMSEVVRMLE 435 + Q+ + C Q RPK +++V +L+ Sbjct: 847 IYQLMMQCWQQERSRRPKFADIVSILD 873
>CPK11_ARATH (O22932) CBL-interacting serine/threonine-protein kinase 11 (EC| 2.7.11.1) (SOS2-like protein kinase PKS5) (SOS-interacting protein 4) (SNF1-related kinase 3.22) Length = 435 Score = 47.0 bits (110), Expect = 3e-05 Identities = 37/109 (33%), Positives = 55/109 (50%), Gaps = 2/109 (1%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMD-YKDTHVTTAVRGTIGHIAPEYLS-TGKSSEKTDVFGY 177 N+L+DE+ V DFGL+ L D + + + GT ++APE LS G K DV+ Sbjct: 150 NLLIDENGNLKVSDFGLSALTDQIRPDGLLHTLCGTPAYVAPEILSKKGYEGAKVDVWSC 209 Query: 178 GIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQ 324 GI+L L+ G F ND +VM + + K E + + PDL+ Sbjct: 210 GIVLFVLVAGYLPF------NDPNVMNM-YKKIYKGEYRFPRWMSPDLK 251
>LCK_CHICK (P42683) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (Protein-tyrosine kinase C-TKL) (p56tk1) Length = 507 Score = 47.0 bits (110), Expect = 3e-05 Identities = 24/68 (35%), Positives = 40/68 (58%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 ANIL+ E + DFGLA+L++ + + I APE ++ G + K+DV+ +G Sbjct: 366 ANILVSEALCCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFG 425 Query: 181 IMLLELIT 204 I+L E++T Sbjct: 426 ILLTEIVT 433
>YES_XIPHE (P27447) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 543 Score = 47.0 bits (110), Expect = 3e-05 Identities = 25/71 (35%), Positives = 41/71 (57%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 ANIL+ ++ + DFGLA+L++ + + I APE G+ + K+DV+ +G Sbjct: 400 ANILVADNLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFG 459 Query: 181 IMLLELITGQR 213 I+L EL+T R Sbjct: 460 ILLTELVTKGR 470
>KPC1_CAEEL (P34722) Protein kinase C-like 1 (EC 2.7.11.13) (PKC)| (Tetradecanoyl phorbol acetate resistant protein 1) Length = 704 Score = 47.0 bits (110), Expect = 3e-05 Identities = 22/72 (30%), Positives = 40/72 (55%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 N+LLD D + DFG+AK ++ + + GT +I+PE + +E D + +G+ Sbjct: 504 NVLLDCDGHIKLADFGMAKTEMNRENGMASTFCGTPDYISPEIIKGQLYNEAVDFWSFGV 563 Query: 184 MLLELITGQRAF 219 ++ E++ GQ F Sbjct: 564 LMYEMLVGQSPF 575
>NEK8_BRARE (Q90XC2) Serine/threonine-protein kinase Nek8 (EC 2.7.11.1)| (NimA-related protein kinase 8) Length = 697 Score = 47.0 bits (110), Expect = 3e-05 Identities = 30/78 (38%), Positives = 47/78 (60%), Gaps = 1/78 (1%) Frame = +1 Query: 4 NILLDEDFEAV-VGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 NILLD+ V +GDFG++K++ K T V GT +I+PE ++K+D++ G Sbjct: 133 NILLDKHQMIVKIGDFGISKILVSKSKAYT--VVGTPCYISPELCEGKPYNQKSDIWALG 190 Query: 181 IMLLELITGQRAFDLARL 234 +L EL + +RAF+ A L Sbjct: 191 CVLYELASLKRAFEAANL 208
>KPCD_RAT (P09215) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 673 Score = 47.0 bits (110), Expect = 3e-05 Identities = 25/72 (34%), Positives = 40/72 (55%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 N++LD+D + DFG+ K + + +T GT +IAPE L K S D + +G+ Sbjct: 476 NVMLDKDGHIKIADFGMCKENIFGENRASTFC-GTPDYIAPEILQGLKYSFSVDWWSFGV 534 Query: 184 MLLELITGQRAF 219 +L E++ GQ F Sbjct: 535 LLYEMLIGQSPF 546
>GPRK2_DROME (P32866) G protein-coupled receptor kinase 2 (EC 2.7.11.16)| Length = 714 Score = 47.0 bits (110), Expect = 3e-05 Identities = 25/76 (32%), Positives = 41/76 (53%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 NILLD+ + D GLA ++ + + GT+G++APE + K + D F +G Sbjct: 440 NILLDDHGHVRISDLGLA--VEIPEGEMVRGRVGTVGYMAPEVIDNEKYAFSPDWFSFGC 497 Query: 184 MLLELITGQRAFDLAR 231 +L E+I GQ F + + Sbjct: 498 LLYEMIEGQAPFRMRK 513
>EPHA6_MOUSE (Q62413) Ephrin type-A receptor 6 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2) Length = 1035 Score = 47.0 bits (110), Expect = 3e-05 Identities = 40/147 (27%), Positives = 72/147 (48%), Gaps = 3/147 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLM--DYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGY 177 NIL++ + V DFGL++++ D + + TT + I APE ++ K S +D + Y Sbjct: 802 NILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDAWSY 861 Query: 178 GIMLLELIT-GQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEA 354 GI++ E+++ G+R + ++N D ++ ++ L M P LQ Sbjct: 862 GIVMWEVMSYGERPY--WEMSNQDVILSIEEGYRL----PAPMGCPPSLQ---------- 905 Query: 355 LIQVALLCTQGSPMDRPKMSEVVRMLE 435 Q+ L C Q RPK +++V L+ Sbjct: 906 --QLMLHCWQKERNHRPKFTDIVSFLD 930
>PKN5_MYXXA (P54737) Serine/threonine-protein kinase pkn5 (EC 2.7.11.1)| Length = 380 Score = 47.0 bits (110), Expect = 3e-05 Identities = 26/76 (34%), Positives = 46/76 (60%), Gaps = 2/76 (2%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVR--GTIGHIAPEYLSTGKSSEKTDVFG 174 +NI++D+D + + DFGLAK + D +T A + GT ++APE + + D++ Sbjct: 248 SNIMVDDDRQVRLMDFGLAKFL-ADDAAITEAGKLVGTYRYMAPEQILGEPLDGRADLYS 306 Query: 175 YGIMLLELITGQRAFD 222 G++L EL++G+ FD Sbjct: 307 LGVILYELLSGRPPFD 322
>NEK1_HUMAN (Q96PY6) Serine/threonine-protein kinase Nek1 (EC 2.7.11.1)| (NimA-related protein kinase 1) (NY-REN-55 antigen) Length = 1258 Score = 47.0 bits (110), Expect = 3e-05 Identities = 37/161 (22%), Positives = 78/161 (48%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 NI L +D +GDFG+A++++ T + GT +++PE + K+D++ G Sbjct: 133 NIFLTKDGTVQLGDFGIARVLNSTVELARTCI-GTPYYLSPEICENKPYNNKSDIWALGC 191 Query: 184 MLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEALIQ 363 +L EL T + AF+ + N ++L + G S++ +++ +L+ Sbjct: 192 VLYELCTLKHAFEAGSMKN----LVLKIISGSFPP-----------VSLHYSYDLRSLVS 236 Query: 364 VALLCTQGSPMDRPKMSEVVRMLEGDGLAERWEEWQKVEVV 486 + +P DRP ++ + LE +A+R E++ +++ Sbjct: 237 QLF---KRNPRDRPSVNSI---LEKGFIAKRIEKFLSPQLI 271
>KPCD_CANFA (Q5PU49) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 674 Score = 47.0 bits (110), Expect = 3e-05 Identities = 25/72 (34%), Positives = 40/72 (55%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 N++LD+D + DFG+ K + + +T GT +IAPE L K S D + +G+ Sbjct: 476 NVMLDQDGHIKIADFGMCKENIFGEKQASTFC-GTPDYIAPEILQGLKYSFSVDWWSFGV 534 Query: 184 MLLELITGQRAF 219 +L E++ GQ F Sbjct: 535 LLYEMLIGQSPF 546
>HCK_RAT (P50545) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 502 Score = 47.0 bits (110), Expect = 3e-05 Identities = 22/68 (32%), Positives = 40/68 (58%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 ANIL+ + DFGLA++++ + + I APE ++ G + K+DV+ +G Sbjct: 361 ANILVSASLVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFG 420 Query: 181 IMLLELIT 204 I+L+E++T Sbjct: 421 ILLMEIVT 428
>ARBK2_HUMAN (P35626) Beta-adrenergic receptor kinase 2 (EC 2.7.11.15)| (Beta-ARK-2) (G-protein-coupled receptor kinase 3) Length = 688 Score = 47.0 bits (110), Expect = 3e-05 Identities = 30/74 (40%), Positives = 39/74 (52%), Gaps = 1/74 (1%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKT-DVFGY 177 ANILLDE A + D GLA K H + GT G++APE L G + + + D F Sbjct: 321 ANILLDEHGHARISDLGLACDFSKKKPHASV---GTHGYMAPEVLQKGTAYDSSADWFSL 377 Query: 178 GIMLLELITGQRAF 219 G ML +L+ G F Sbjct: 378 GCMLFKLLRGHSPF 391
>HCK_MOUSE (P08103) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK) Length = 523 Score = 47.0 bits (110), Expect = 3e-05 Identities = 22/68 (32%), Positives = 40/68 (58%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 ANIL+ + DFGLA++++ + + I APE ++ G + K+DV+ +G Sbjct: 382 ANILVSASLVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFG 441 Query: 181 IMLLELIT 204 I+L+E++T Sbjct: 442 ILLMEIVT 449
>PKNA_MYCTU (P65726) Probable serine/threonine-protein kinase pknA (EC| 2.7.11.1) Length = 431 Score = 47.0 bits (110), Expect = 3e-05 Identities = 25/72 (34%), Positives = 39/72 (54%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 NIL+ + + DFG+AK +D T V GT +IAPE +S +DV+ G+ Sbjct: 146 NILITPTGQVKITDFGIAKAVDAAPVTQTGMVMGTAQYIAPEQALGHDASPASDVYSLGV 205 Query: 184 MLLELITGQRAF 219 + E ++G+R F Sbjct: 206 VGYEAVSGKRPF 217
>PKNA_MYCBO (P65727) Probable serine/threonine-protein kinase pknA (EC| 2.7.11.1) Length = 431 Score = 47.0 bits (110), Expect = 3e-05 Identities = 25/72 (34%), Positives = 39/72 (54%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 NIL+ + + DFG+AK +D T V GT +IAPE +S +DV+ G+ Sbjct: 146 NILITPTGQVKITDFGIAKAVDAAPVTQTGMVMGTAQYIAPEQALGHDASPASDVYSLGV 205 Query: 184 MLLELITGQRAF 219 + E ++G+R F Sbjct: 206 VGYEAVSGKRPF 217
>PLK1_XENTR (P62205) Serine/threonine-protein kinase PLK1 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-1) (Plx1) Length = 598 Score = 47.0 bits (110), Expect = 3e-05 Identities = 25/77 (32%), Positives = 43/77 (55%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 N+ L+++ E +GDFGLA ++Y D + GT +IAPE L S + D++ G Sbjct: 172 NLFLNDEMEVKIGDFGLATKVEY-DGERKKTLCGTPNYIAPEVLGKKGHSFEVDIWSIGC 230 Query: 184 MLLELITGQRAFDLARL 234 ++ L+ G+ F+ + L Sbjct: 231 IMYTLLVGKPPFETSCL 247
>PLK1_XENLA (P70032) Serine/threonine-protein kinase PLK1 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-1) (Plx1) Length = 598 Score = 47.0 bits (110), Expect = 3e-05 Identities = 25/77 (32%), Positives = 43/77 (55%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 N+ L+++ E +GDFGLA ++Y D + GT +IAPE L S + D++ G Sbjct: 172 NLFLNDEMEVKIGDFGLATKVEY-DGERKKTLCGTPNYIAPEVLGKKGHSFEVDIWSIGC 230 Query: 184 MLLELITGQRAFDLARL 234 ++ L+ G+ F+ + L Sbjct: 231 IMYTLLVGKPPFETSCL 247
>KS6A4_MOUSE (Q9Z2B9) Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (RSK-like protein kinase) (RLSK) Length = 773 Score = 47.0 bits (110), Expect = 3e-05 Identities = 28/75 (37%), Positives = 42/75 (56%), Gaps = 1/75 (1%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYL-STGKSSEKTDVFGYG 180 N+LLD + V+ DFGL+K ++ T + GTI ++APE + S + D + G Sbjct: 166 NVLLDSEGHIVLTDFGLSKEFLTEEKERTFSFCGTIEYMAPEIIRSKAGHGKAVDWWSLG 225 Query: 181 IMLLELITGQRAFDL 225 I+L EL+TG F L Sbjct: 226 ILLFELLTGASPFTL 240 Score = 32.3 bits (72), Expect = 0.69 Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 3/75 (4%) Frame = +1 Query: 4 NILLDEDFEAV---VGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFG 174 NIL +D + DFG A+L T+ + APE L+ E D++ Sbjct: 535 NILYADDTPGAPVKIIDFGFARLRPQSPAEPMQTPCFTLQYAAPELLAQQGYDESCDLWS 594 Query: 175 YGIMLLELITGQRAF 219 G++L +++GQ F Sbjct: 595 LGVILYMMLSGQVPF 609
>ABL_FSVHY (P10447) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 439 Score = 47.0 bits (110), Expect = 3e-05 Identities = 44/143 (30%), Positives = 68/143 (47%), Gaps = 4/143 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGT---IGHIAPEYLSTGKSSEKTDVFG 174 N L+ E+ V DFGL++LM DT+ TA GT I APE L+ K S K+DV+ Sbjct: 317 NCLVGENHLVKVADFGLSRLMT-GDTY--TAHAGTKFPIKWTAPESLAYNKFSIKSDVWA 373 Query: 175 YGIMLLELIT-GQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVE 351 +G++L E+ T G + L+ +V L++ D + E E Sbjct: 374 FGVLLWEIATYGMSPYPGIDLS------------------QVYELLEKDYRMERPEGCPE 415 Query: 352 ALIQVALLCTQGSPMDRPKMSEV 420 + ++ C Q +P DRP +E+ Sbjct: 416 KVYELMRACWQWNPSDRPAFAEI 438
>RIPK3_RAT (Q9Z2P5) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (Homocysteine respondent protein HCYP2) Length = 478 Score = 46.6 bits (109), Expect = 4e-05 Identities = 24/76 (31%), Positives = 45/76 (59%), Gaps = 4/76 (5%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVR---GTIGHIAPEYLST-GKSSEKTDV 168 +N+LLD + A + DFGL+ + + R GT+ ++APE L GK+S+ +DV Sbjct: 147 SNVLLDLELHAKLADFGLSTFQGGSQSGSGSGSRDSGGTLAYLAPELLDNDGKASKASDV 206 Query: 169 FGYGIMLLELITGQRA 216 + +G+++ ++ G+ A Sbjct: 207 YSFGVLVWTVLAGREA 222
>LYN_MOUSE (P25911) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 46.6 bits (109), Expect = 4e-05 Identities = 36/127 (28%), Positives = 59/127 (46%), Gaps = 17/127 (13%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 AN+L+ E + DFGLA++++ + + I APE ++ G + K+DV+ +G Sbjct: 370 ANVLVSESLMCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFG 429 Query: 181 IMLLELITG-----------------QRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLV 309 I+L E++T + + + R+ N D L D +K KEK E Sbjct: 430 ILLYEIVTYGKIPYPGRTNADVMSALSQGYRMPRMENCPD-ELYDIMKMCWKEKAEERPT 488 Query: 310 DPDLQSV 330 LQSV Sbjct: 489 FDYLQSV 495
>EPHA5_CHICK (P54755) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK7) Length = 1013 Score = 46.6 bits (109), Expect = 4e-05 Identities = 40/147 (27%), Positives = 71/147 (48%), Gaps = 3/147 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLM--DYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGY 177 NIL++ + V DFGL++++ D + + T + I APE ++ K + +DV+ Y Sbjct: 781 NILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSY 840 Query: 178 GIMLLELIT-GQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEA 354 GI++ E+++ G+R + + N D + + E+ + D + A Sbjct: 841 GIVMWEVMSYGERPY--WEMTNQDVIKAV--------EEGYRLPSPMDCPA--------A 882 Query: 355 LIQVALLCTQGSPMDRPKMSEVVRMLE 435 L Q+ L C Q RPK E+V ML+ Sbjct: 883 LYQLMLDCWQKDRNSRPKFDEIVSMLD 909
>SRC64_DROME (P00528) Tyrosine-protein kinase Src64B (EC 2.7.10.2) (Dsrc64)| Length = 552 Score = 46.6 bits (109), Expect = 4e-05 Identities = 26/67 (38%), Positives = 40/67 (59%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 N+L+ E+ A + DFGLA+++ + R + APE + GK S K+DV+ YGI Sbjct: 409 NVLIGENNVAKICDFGLARVIADDEYCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYGI 468 Query: 184 MLLELIT 204 +L+EL T Sbjct: 469 LLMELFT 475
>KPC1_DROME (P05130) Protein kinase C, brain isozyme (EC 2.7.11.13) (PKC)| (dPKC53E(BR)) Length = 679 Score = 46.6 bits (109), Expect = 4e-05 Identities = 26/73 (35%), Positives = 37/73 (50%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 N+LLD D + DFG+ K D T GT +IAPE + + D + YG+ Sbjct: 479 NVLLDADGHVKIADFGMCKENIVGDK-TTKTFCGTPDYIAPEIILYQPYGKSVDWWAYGV 537 Query: 184 MLLELITGQRAFD 222 +L E++ GQ FD Sbjct: 538 LLYEMLVGQPPFD 550
>KS6A4_HUMAN (O75676) Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (Ribosomal protein kinase B) (RSKB) Length = 772 Score = 46.6 bits (109), Expect = 4e-05 Identities = 28/75 (37%), Positives = 42/75 (56%), Gaps = 1/75 (1%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEK-TDVFGYG 180 N+LLD + V+ DFGL+K ++ T + GTI ++APE + + K D + G Sbjct: 166 NVLLDSEGHIVLTDFGLSKEFLTEEKERTFSFCGTIEYMAPEIIRSKTGHGKAVDWWSLG 225 Query: 181 IMLLELITGQRAFDL 225 I+L EL+TG F L Sbjct: 226 ILLFELLTGASPFTL 240 Score = 30.4 bits (67), Expect = 2.6 Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 3/75 (4%) Frame = +1 Query: 4 NILLDEDFEAV---VGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFG 174 NIL +D + DFG A+L T+ + APE L+ E D++ Sbjct: 535 NILYADDTPGAPVKIIDFGFARLRPQSPGVPMQTPCFTLQYAAPELLAQQGYDESCDLWS 594 Query: 175 YGIMLLELITGQRAF 219 G++L +++GQ F Sbjct: 595 LGVILYMMLSGQVPF 609
>FGR_FSVGR (P00544) Tyrosine-protein kinase transforming protein Fgr (EC| 2.7.10.2) Length = 545 Score = 46.6 bits (109), Expect = 4e-05 Identities = 26/71 (36%), Positives = 41/71 (57%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 ANIL+ E + DFGLA+L++ + + + I APE G+ + K+DV+ +G Sbjct: 409 ANILVGERLVCKIADFGLARLIEDNEYNPRQGAKFPIKWTAPEAALFGRFTIKSDVWSFG 468 Query: 181 IMLLELITGQR 213 I+L ELI+ R Sbjct: 469 ILLTELISKGR 479
>KPC1B_CAEEL (P34885) Protein kinase C-like 1B (EC 2.7.11.13) (PKC1B)| Length = 707 Score = 46.6 bits (109), Expect = 4e-05 Identities = 31/95 (32%), Positives = 48/95 (50%), Gaps = 6/95 (6%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 NILLD + + DFG+ K KD ++T+ GT +IAPE L + D + G+ Sbjct: 507 NILLDAEGHCRLADFGMCKEGINKD-NLTSTFCGTPDYIAPEILQEMEYGVSVDWWALGV 565 Query: 184 MLLELITGQRAF------DLARLANDDDVMLLDWV 270 ++ E++ GQ F DL +DDV+ W+ Sbjct: 566 LMYEMMAGQPPFEADNEDDLFEAILNDDVLYPVWL 600
>EPHA6_RAT (P54758) Ephrin type-A receptor 6 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2) Length = 1035 Score = 46.6 bits (109), Expect = 4e-05 Identities = 40/147 (27%), Positives = 72/147 (48%), Gaps = 3/147 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLM--DYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGY 177 NIL++ + V DFGL++++ D + + TT + I APE ++ K S +DV+ Y Sbjct: 802 NILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDVWSY 861 Query: 178 GIMLLELIT-GQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEA 354 GI++ E+++ G+R + ++N D ++ ++ L M P L Sbjct: 862 GIVMWEVMSYGERPY--WEMSNQDVILSIEEGYRL----PAPMGCPPSLH---------- 905 Query: 355 LIQVALLCTQGSPMDRPKMSEVVRMLE 435 Q+ L C Q RPK +++V L+ Sbjct: 906 --QLMLHCWQKERNHRPKFTDIVSFLD 930
>EPHA5_RAT (P54757) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) Length = 1005 Score = 46.6 bits (109), Expect = 4e-05 Identities = 39/147 (26%), Positives = 71/147 (48%), Gaps = 3/147 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLM--DYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGY 177 NIL++ + V DFGL++++ D + + T + I APE ++ K + +DV+ Y Sbjct: 807 NILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSY 866 Query: 178 GIMLLELIT-GQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEA 354 GI++ E+++ G+R + + N D + + E+ + D + A Sbjct: 867 GIVMWEVVSYGERPY--WEMTNQDVIKAV--------EEGYRLPSPMDCPA--------A 908 Query: 355 LIQVALLCTQGSPMDRPKMSEVVRMLE 435 L Q+ L C Q RPK ++V ML+ Sbjct: 909 LYQLMLDCWQKDRNSRPKFDDIVNMLD 935
>MATK_RAT (P41243) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase BATK) Length = 467 Score = 46.6 bits (109), Expect = 4e-05 Identities = 29/71 (40%), Positives = 40/71 (56%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 NIL+ ED A V DFGLAK K + R + APE L G+ S K+DV+ +G+ Sbjct: 316 NILVSEDLVAKVSDFGLAKAELRKGLDSS---RLPVKWTAPEALKNGRFSSKSDVWSFGV 372 Query: 184 MLLELITGQRA 216 +L E+ + RA Sbjct: 373 LLWEVFSYGRA 383
>MATK_MOUSE (P41242) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK) Length = 505 Score = 46.6 bits (109), Expect = 4e-05 Identities = 28/71 (39%), Positives = 40/71 (56%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 NIL+ ED A V DFGLAK + + R + APE L G+ S K+DV+ +G+ Sbjct: 355 NILVSEDLVAKVSDFGLAKA----ERKGLDSSRLPVKWTAPEALKNGRFSSKSDVWSFGV 410 Query: 184 MLLELITGQRA 216 +L E+ + RA Sbjct: 411 LLWEVFSYGRA 421
>EPHA3_BRARE (O13146) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ZEK1) (EPH-like kinase 1) Length = 981 Score = 46.6 bits (109), Expect = 4e-05 Identities = 39/147 (26%), Positives = 73/147 (49%), Gaps = 3/147 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLM--DYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGY 177 NIL++ + V DFGL++++ D + + T + I APE ++ K + +DV+ Y Sbjct: 756 NILVNRNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAITYRKFTSASDVWSY 815 Query: 178 GIMLLELIT-GQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEA 354 GI++ E+I+ G+R + ++N D + +D +G ++ V Sbjct: 816 GIVMWEVISYGERPY--WEMSNQDVIKAVD--EGYRLPAPMDCPV--------------V 857 Query: 355 LIQVALLCTQGSPMDRPKMSEVVRMLE 435 L Q+ L C + + DRPK ++V L+ Sbjct: 858 LHQLMLDCWEKNRSDRPKFGQIVNTLD 884
>CDS1_SCHPO (Q09170) Serine/threonine-protein kinase cds1 (EC 2.7.11.1)| (Checkpoint kinase cds1) Length = 460 Score = 46.6 bits (109), Expect = 4e-05 Identities = 27/78 (34%), Positives = 42/78 (53%), Gaps = 6/78 (7%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLST------GKSSEKTD 165 NIL+ DF + DFGLAK++ T + T GT+G++APE L + G +K D Sbjct: 299 NILITNDFHLKISDFGLAKVIHGTGTFLETFC-GTMGYLAPEVLKSKNVNLDGGYDDKVD 357 Query: 166 VFGYGIMLLELITGQRAF 219 ++ G +L ++T F Sbjct: 358 IWSLGCVLYVMLTASIPF 375
>KPCD_HUMAN (Q05655) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 676 Score = 46.6 bits (109), Expect = 4e-05 Identities = 25/72 (34%), Positives = 40/72 (55%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 N+LLD D + DFG+ K + ++ +T GT +IAPE L K + D + +G+ Sbjct: 478 NVLLDRDGHIKIADFGMCKENIFGESRASTFC-GTPDYIAPEILQGLKYTFSVDWWSFGV 536 Query: 184 MLLELITGQRAF 219 +L E++ GQ F Sbjct: 537 LLYEMLIGQSPF 548
>PKNA_MYCLE (P54743) Probable serine/threonine-protein kinase pknA (EC| 2.7.11.1) Length = 437 Score = 46.6 bits (109), Expect = 4e-05 Identities = 24/72 (33%), Positives = 40/72 (55%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 NIL+ + + DFG+AK +D T V GT +IAPE ++ +DV+ G+ Sbjct: 146 NILITPTGQVKITDFGIAKAVDAAPVTQTGMVMGTAQYIAPEQALGHDATPASDVYSLGV 205 Query: 184 MLLELITGQRAF 219 + E+++G+R F Sbjct: 206 IGYEVVSGKRPF 217
>KAPC_YEAST (P05986) cAMP-dependent protein kinase type 3 (EC 2.7.11.11) (PKA| 3) Length = 398 Score = 46.2 bits (108), Expect = 5e-05 Identities = 25/72 (34%), Positives = 41/72 (56%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 NILLD++ + DFG AK + VT + GT +IAPE +ST ++ D + +G+ Sbjct: 216 NILLDKNGHIKITDFGFAKYVP----DVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGV 271 Query: 184 MLLELITGQRAF 219 ++ E++ G F Sbjct: 272 LIYEMLAGYTPF 283
>KAPA_YEAST (P06244) cAMP-dependent protein kinase type 1 (EC 2.7.11.11) (PKA| 1) (CDC25-suppressing protein kinase) (PK-25) Length = 397 Score = 46.2 bits (108), Expect = 5e-05 Identities = 26/72 (36%), Positives = 41/72 (56%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 NILLD++ + DFG AK + VT + GT +IAPE +ST ++ D + +GI Sbjct: 215 NILLDKNGHIKITDFGFAKYVP----DVTYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGI 270 Query: 184 MLLELITGQRAF 219 ++ E++ G F Sbjct: 271 LIYEMLAGYTPF 282
>ANKK1_MOUSE (Q8BZ25) Ankyrin repeat and protein kinase domain-containing| protein 1 (EC 2.7.11.1) Length = 745 Score = 46.2 bits (108), Expect = 5e-05 Identities = 41/141 (29%), Positives = 69/141 (48%), Gaps = 7/141 (4%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMD---YKDTHVTTAVRGTIGHIAPE-YLSTGKS-SEKTDV 168 NILLD + + DFGL+K M+ K +A+RGT+ +I PE +L K+ + DV Sbjct: 162 NILLDNNMHVKISDFGLSKWMEQSTQKQYIERSALRGTLSYIPPEMFLENNKAPGPEYDV 221 Query: 169 FGYGIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVE--H 342 + + I++ E++T ++ + A L N +++ +V + P LQ V E Sbjct: 222 YSFAIVIWEILTQKKPY--AGL-NMMTIII-----------RVAAGMRPSLQDVSDEWPE 267 Query: 343 EVEALIQVALLCTQGSPMDRP 405 EV ++ + C P RP Sbjct: 268 EVHQMVNLMKRCWDQDPKKRP 288
>CTR1_ARATH (Q05609) Serine/threonine-protein kinase CTR1 (EC 2.7.11.1)| Length = 821 Score = 46.2 bits (108), Expect = 5e-05 Identities = 39/144 (27%), Positives = 72/144 (50%), Gaps = 1/144 (0%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTT-AVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 N+L+D+ + V DFGL++L T +++ + GT +APE L S+EK+DV+ +G Sbjct: 681 NLLVDKKYTVKVCDFGLSRLK--ASTFLSSKSAAGTPEWMAPEVLRDEPSNEKSDVYSFG 738 Query: 181 IMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEALI 360 ++L EL T Q+ + N + ++ V K ++ ++P +V A+I Sbjct: 739 VILWELATLQQPW-----GNLNPAQVVAAVGFKCKRLEIPRNLNP---------QVAAII 784 Query: 361 QVALLCTQGSPMDRPKMSEVVRML 432 + C P RP + ++ +L Sbjct: 785 EG---CWTNEPWKRPSFATIMDLL 805
>KPCT_MOUSE (Q02111) Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)| Length = 707 Score = 46.2 bits (108), Expect = 5e-05 Identities = 32/108 (29%), Positives = 50/108 (46%), Gaps = 6/108 (5%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 NILLD D + DFG+ K D T GT +IAPE L K + D + +G+ Sbjct: 509 NILLDRDGHIKIADFGMCKENMLGDAKTNTFC-GTPDYIAPEILLGQKYNHSVDWWSFGV 567 Query: 184 MLLELITGQRAF------DLARLANDDDVMLLDWVKGLLKEKKVEMLV 309 ++ E++ GQ F +L D+ W++ K+ V++ V Sbjct: 568 LVYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWLEREAKDLLVKLFV 615
>KPCA_RAT (P05696) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 46.2 bits (108), Expect = 5e-05 Identities = 24/73 (32%), Positives = 38/73 (52%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 N++LD + + DFG+ K D T GT +IAPE ++ + D + YG+ Sbjct: 467 NVMLDSEGHIKIADFGMCK-EHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGV 525 Query: 184 MLLELITGQRAFD 222 +L E++ GQ FD Sbjct: 526 LLYEMLAGQPPFD 538
>KPCA_RABIT (P10102) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 46.2 bits (108), Expect = 5e-05 Identities = 24/73 (32%), Positives = 38/73 (52%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 N++LD + + DFG+ K D T GT +IAPE ++ + D + YG+ Sbjct: 467 NVMLDSEGHIKIADFGMCK-EHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGV 525 Query: 184 MLLELITGQRAFD 222 +L E++ GQ FD Sbjct: 526 LLYEMLAGQPPFD 538
>KPCA_HUMAN (P17252) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 46.2 bits (108), Expect = 5e-05 Identities = 24/73 (32%), Positives = 38/73 (52%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 N++LD + + DFG+ K D T GT +IAPE ++ + D + YG+ Sbjct: 467 NVMLDSEGHIKIADFGMCK-EHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGV 525 Query: 184 MLLELITGQRAFD 222 +L E++ GQ FD Sbjct: 526 LLYEMLAGQPPFD 538
>KPCA_BOVIN (P04409) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 46.2 bits (108), Expect = 5e-05 Identities = 24/73 (32%), Positives = 38/73 (52%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 N++LD + + DFG+ K D T GT +IAPE ++ + D + YG+ Sbjct: 467 NVMLDSEGHIKIADFGMCK-EHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGV 525 Query: 184 MLLELITGQRAFD 222 +L E++ GQ FD Sbjct: 526 LLYEMLAGQPPFD 538
>YES_XENLA (P10936) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 536 Score = 46.2 bits (108), Expect = 5e-05 Identities = 36/145 (24%), Positives = 65/145 (44%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 ANIL+ ++ + DFGLA+L++ + + I APE G+ + K+DV+ +G Sbjct: 393 ANILVGDNLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFG 452 Query: 181 IMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEALI 360 I+L EL+ R G++ + +E V+ + + E+L Sbjct: 453 ILLTELVAKGRV----------------PYPGMVNREVLEQ-VERGYRMPCPQRCPESLH 495 Query: 361 QVALLCTQGSPMDRPKMSEVVRMLE 435 ++ LC + P +RP + LE Sbjct: 496 ELMKLCWKKDPDERPTFEYIQSFLE 520
>FGR_HUMAN (P09769) Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2)| (P55-FGR) (C-FGR) Length = 529 Score = 46.2 bits (108), Expect = 5e-05 Identities = 27/71 (38%), Positives = 40/71 (56%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 ANIL+ E + DFGLA+L+ + + + I APE G+ + K+DV+ +G Sbjct: 386 ANILVGERLACKIADFGLARLIKDDEYNPCQGSKFPIKWTAPEAALFGRFTIKSDVWSFG 445 Query: 181 IMLLELITGQR 213 I+L ELIT R Sbjct: 446 ILLTELITKGR 456
>LYN_RAT (Q07014) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 46.2 bits (108), Expect = 5e-05 Identities = 22/68 (32%), Positives = 40/68 (58%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 AN+L+ E + DFGLA++++ + + I APE ++ G + K+DV+ +G Sbjct: 370 ANVLVSESLMCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFG 429 Query: 181 IMLLELIT 204 I+L E++T Sbjct: 430 ILLYEIVT 437
>LYN_HUMAN (P07948) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 46.2 bits (108), Expect = 5e-05 Identities = 22/68 (32%), Positives = 40/68 (58%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 AN+L+ E + DFGLA++++ + + I APE ++ G + K+DV+ +G Sbjct: 370 ANVLVSESLMCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFG 429 Query: 181 IMLLELIT 204 I+L E++T Sbjct: 430 ILLYEIVT 437
>TNI3K_MOUSE (Q5GIG6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 833 Score = 46.2 bits (108), Expect = 5e-05 Identities = 28/73 (38%), Positives = 39/73 (53%), Gaps = 1/73 (1%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPE-YLSTGKSSEKTDVFGYG 180 NILL ED AVV DFG ++ + D T G + +APE + + + K DVF Y Sbjct: 591 NILLYEDGHAVVADFGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYA 650 Query: 181 IMLLELITGQRAF 219 + L EL+ G+ F Sbjct: 651 LCLWELLIGEIPF 663
>YES_HUMAN (P07947) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 542 Score = 46.2 bits (108), Expect = 5e-05 Identities = 25/71 (35%), Positives = 40/71 (56%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 ANIL+ E+ + DFGLA+L++ + + I APE G+ + K+DV+ +G Sbjct: 399 ANILVGENLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFG 458 Query: 181 IMLLELITGQR 213 I+ EL+T R Sbjct: 459 ILQTELVTKGR 469
>E2AK2_HUMAN (P19525) Interferon-induced, double-stranded RNA-activated protein| kinase (EC 2.7.11.1) (Interferon-inducible RNA-dependent protein kinase) (Protein kinase RNA-activated) (PKR) (p68 kinase) (P1/eIF-2A protein kinase) Length = 551 Score = 45.8 bits (107), Expect = 6e-05 Identities = 37/145 (25%), Positives = 67/145 (46%), Gaps = 1/145 (0%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 +NI L + + +GDFGL + K+ T +GT+ +++PE +S+ ++ D++ G Sbjct: 418 SNIFLVDTKQVKIGDFGLVTSL--KNDGKRTRSKGTLRYMSPEQISSQDYGKEVDLYALG 475 Query: 181 IMLLELI-TGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEAL 357 ++L EL+ AF+ ++ D L D + + +KK + L+ L Sbjct: 476 LILAELLHVCDTAFETSKFFTD----LRDGIISDIFDKKEKTLLQKLLSK---------- 521 Query: 358 IQVALLCTQGSPMDRPKMSEVVRML 432 P DRP SE++R L Sbjct: 522 ----------KPEDRPNTSEILRTL 536
>FGFR1_DROME (Q07407) Fibroblast growth factor receptor homolog 1 precursor (EC| 2.7.10.1) (Protein heartless) Length = 729 Score = 45.8 bits (107), Expect = 6e-05 Identities = 43/162 (26%), Positives = 76/162 (46%), Gaps = 2/162 (1%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTH-VTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 N+L+ +D+ + DFGLA+ + D + T R I +APE L K+DV+ YG Sbjct: 561 NVLVSDDYVLKIADFGLARDIQSTDYYRKNTNGRLPIKWMAPESLQEKFYDSKSDVWSYG 620 Query: 181 IMLLELIT-GQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEAL 357 I+L E++T GQ+ + A + L+ + + K K M ++Y+ Sbjct: 621 ILLWEIMTYGQQPYPTIMSAEELYTYLMSGQR-MEKPAKCSM-------NIYI------- 665 Query: 358 IQVALLCTQGSPMDRPKMSEVVRMLEGDGLAERWEEWQKVEV 483 + C + DRP +E+V + D L + E++ V++ Sbjct: 666 --LMRQCWHFNADDRPPFTEIVEYM--DKLLQTKEDYLDVDI 703
>TESK1_HUMAN (Q15569) Dual specificity testis-specific protein kinase 1 (EC| 2.7.12.1) (Testicular protein kinase 1) Length = 626 Score = 45.8 bits (107), Expect = 6e-05 Identities = 31/65 (47%), Positives = 38/65 (58%), Gaps = 3/65 (4%) Frame = +1 Query: 16 DEDFEAVVGDFGLA-KLMDYKD--THVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGIM 186 D F AVVGDFGLA K+ Y++ AV G+ +APE L EK DVF +GI+ Sbjct: 187 DRGFTAVVGDFGLAEKIPVYREGARKEPLAVVGSPYWMAPEVLRGELYDEKADVFAFGIV 246 Query: 187 LLELI 201 L ELI Sbjct: 247 LCELI 251
>NEK1_MOUSE (P51954) Serine/threonine-protein kinase Nek1 (EC 2.7.11.1)| (NimA-related protein kinase 1) Length = 1203 Score = 45.8 bits (107), Expect = 6e-05 Identities = 37/161 (22%), Positives = 77/161 (47%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 NI L +D +GDFG+A++++ T + GT +++PE + K+D++ G Sbjct: 133 NIFLTKDGTVQLGDFGIARVLNSTVELARTCI-GTPYYLSPEICENKPYNNKSDIWALGC 191 Query: 184 MLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEALIQ 363 +L EL T + AF+ + N ++L + G S + +++ +L+ Sbjct: 192 VLYELCTLKHAFEAGNMKN----LVLKIISGSFPP-----------VSPHYSYDLRSLLS 236 Query: 364 VALLCTQGSPMDRPKMSEVVRMLEGDGLAERWEEWQKVEVV 486 + +P DRP ++ + LE +A+R E++ +++ Sbjct: 237 QLF---KRNPRDRPSVNSI---LEKGFIAKRIEKFLSPQLI 271
>PKN1_THETN (Q8R9T6) Probable serine/threonine-protein kinase Sps1 (EC| 2.7.11.1) Length = 625 Score = 45.8 bits (107), Expect = 6e-05 Identities = 24/73 (32%), Positives = 40/73 (54%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 NIL+ ++ V DFG+A+ + T V GT + +PE E+TD++ GI Sbjct: 139 NILVTDEDVVKVTDFGIARAANGATITYTGDVIGTAYYFSPEQAKGSIVDERTDIYSLGI 198 Query: 184 MLLELITGQRAFD 222 +L E++TG+ F+ Sbjct: 199 VLFEMLTGKVPFE 211
>KS6AA_CHICK (P18652) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 752 Score = 45.8 bits (107), Expect = 6e-05 Identities = 25/73 (34%), Positives = 43/73 (58%), Gaps = 1/73 (1%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAK-LMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 NILLDE+ + DFGL+K +D++ + GT+ ++APE ++ S D + YG Sbjct: 210 NILLDEEGHIKLTDFGLSKEAIDHEKKAYSFC--GTVEYMAPEVVNRQGHSHSADWWSYG 267 Query: 181 IMLLELITGQRAF 219 +++ E++TG F Sbjct: 268 VLMFEMLTGSLPF 280
>GRK2_CAEEL (Q09639) G protein-coupled receptor kinase 2 (EC 2.7.11.16)| Length = 707 Score = 45.8 bits (107), Expect = 6e-05 Identities = 30/74 (40%), Positives = 40/74 (54%), Gaps = 1/74 (1%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKT-DVFGY 177 ANILLDE+ V D GLA K H + GT G++APE L+ G + + + D F Sbjct: 322 ANILLDENGHVRVSDLGLACDYSKKKPHASV---GTHGYMAPEVLAKGVAYDSSADWFSL 378 Query: 178 GIMLLELITGQRAF 219 G ML +L+ G F Sbjct: 379 GCMLYKLLKGHSPF 392
>KPCD_MOUSE (P28867) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 674 Score = 45.8 bits (107), Expect = 6e-05 Identities = 25/72 (34%), Positives = 39/72 (54%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 N++LD D + DFG+ K + + +T GT +IAPE L K S D + +G+ Sbjct: 476 NVMLDRDGHIKIADFGMCKENIFGEGRASTFC-GTPDYIAPEILQGLKYSFSVDWWSFGV 534 Query: 184 MLLELITGQRAF 219 +L E++ GQ F Sbjct: 535 LLYEMLIGQSPF 546
>TESK1_MOUSE (O70146) Dual specificity testis-specific protein kinase 1 (EC| 2.7.12.1) (Testicular protein kinase 1) Length = 627 Score = 45.8 bits (107), Expect = 6e-05 Identities = 31/65 (47%), Positives = 38/65 (58%), Gaps = 3/65 (4%) Frame = +1 Query: 16 DEDFEAVVGDFGLA-KLMDYKD--THVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGIM 186 D F AVVGDFGLA K+ Y++ AV G+ +APE L EK DVF +GI+ Sbjct: 182 DRGFTAVVGDFGLAEKIPVYREGTRKEPLAVVGSPYWMAPEVLRGELYDEKADVFAFGIV 241 Query: 187 LLELI 201 L ELI Sbjct: 242 LCELI 246
>YES_MOUSE (Q04736) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 540 Score = 45.8 bits (107), Expect = 6e-05 Identities = 25/71 (35%), Positives = 40/71 (56%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 ANIL+ E+ + DFGLA+L++ + + I APE G+ + K+DV+ +G Sbjct: 397 ANILVGENLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFG 456 Query: 181 IMLLELITGQR 213 I+ EL+T R Sbjct: 457 ILQTELVTKGR 467
>PKN1_COREF (Q8FUI5) Probable serine/threonine protein kinase CE0033 (EC| 2.7.11.1) Length = 660 Score = 45.8 bits (107), Expect = 6e-05 Identities = 25/76 (32%), Positives = 44/76 (57%), Gaps = 2/76 (2%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVT--TAVRGTIGHIAPEYLSTGKSSEKTDVFG 174 ANI+++ V DFG+A+ +D + +T AV GT +++PE + ++DV+ Sbjct: 140 ANIMINNTGGVKVMDFGIARALDDSTSAMTQTAAVIGTAQYLSPEQARGKPADARSDVYA 199 Query: 175 YGIMLLELITGQRAFD 222 G +L EL+TG+ F+ Sbjct: 200 AGCVLYELVTGRPPFE 215
>KS6AA_XENLA (P10665) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 733 Score = 45.8 bits (107), Expect = 6e-05 Identities = 25/73 (34%), Positives = 43/73 (58%), Gaps = 1/73 (1%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAK-LMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 NILLDE+ + DFGL+K +D++ + GT+ ++APE ++ S D + YG Sbjct: 192 NILLDEEGHIKLTDFGLSKEAIDHEKKAYSFC--GTVEYMAPEVVNRQGHSHSADWWSYG 249 Query: 181 IMLLELITGQRAF 219 +++ E++TG F Sbjct: 250 VLMFEMLTGSLPF 262 Score = 29.3 bits (64), Expect = 5.8 Identities = 25/77 (32%), Positives = 39/77 (50%), Gaps = 4/77 (5%) Frame = +1 Query: 1 ANIL-LDE--DFEAV-VGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDV 168 +NIL +DE D E++ + DFG AK + + + T T +APE L E D+ Sbjct: 537 SNILYVDESGDPESIRICDFGFAKQLRADNGLLMTPCY-TANFVAPEVLKRQGYDEGCDI 595 Query: 169 FGYGIMLLELITGQRAF 219 + GI+L ++ G F Sbjct: 596 WSLGILLYTMLAGYTPF 612
>KS6A2_MOUSE (Q9WUT3) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (Protein-tyrosine kinase Mpk-9) (MAP kinase-activated protein kinase 1c) (M Length = 733 Score = 45.8 bits (107), Expect = 6e-05 Identities = 24/72 (33%), Positives = 41/72 (56%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 NILLDE+ + DFGL+K D + GTI ++APE ++ ++ D + +G+ Sbjct: 189 NILLDEEGHIKITDFGLSKEATDHDKRAYSFC-GTIEYMAPEVVNRRGHTQSADWWSFGV 247 Query: 184 MLLELITGQRAF 219 ++ E++TG F Sbjct: 248 LMFEMLTGSLPF 259
>EPHA2_HUMAN (P29317) Ephrin type-A receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) Length = 976 Score = 45.8 bits (107), Expect = 6e-05 Identities = 37/147 (25%), Positives = 71/147 (48%), Gaps = 3/147 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLM--DYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGY 177 NIL++ + V DFGL++++ D + T+ T+ + I APE +S K + +DV+ + Sbjct: 744 NILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGGKIPIRWTAPEAISYRKFTSASDVWSF 803 Query: 178 GIMLLELIT-GQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEA 354 GI++ E++T G+R + W L +V ++ + A Sbjct: 804 GIVMWEVMTYGERPY---------------WE---LSNHEVMKAINDGFRLPTPMDCPSA 845 Query: 355 LIQVALLCTQGSPMDRPKMSEVVRMLE 435 + Q+ + C Q RPK +++V +L+ Sbjct: 846 IYQLMMQCWQQERARRPKFADIVSILD 872
>KS6A1_HUMAN (Q15418) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 45.8 bits (107), Expect = 6e-05 Identities = 25/73 (34%), Positives = 43/73 (58%), Gaps = 1/73 (1%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAK-LMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 NILLDE+ + DFGL+K +D++ + GT+ ++APE ++ S D + YG Sbjct: 192 NILLDEEGHIKLTDFGLSKEAIDHEKKAYSFC--GTVEYMAPEVVNRQGHSHSADWWSYG 249 Query: 181 IMLLELITGQRAF 219 +++ E++TG F Sbjct: 250 VLMFEMLTGSLPF 262 Score = 29.6 bits (65), Expect = 4.4 Identities = 18/59 (30%), Positives = 28/59 (47%) Frame = +1 Query: 43 DFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGIMLLELITGQRAF 219 DFG AK + ++ + T T +APE L E D++ GI+L ++ G F Sbjct: 557 DFGFAKQLRAENGLLMTPCY-TANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPF 614
>TOPK_BRARE (Q6DHU8) T-lymphokine-activated killer cell-originated protein| kinase homolog (EC 2.7.12.2) (PDZ-binding kinase) Length = 339 Score = 45.8 bits (107), Expect = 6e-05 Identities = 40/167 (23%), Positives = 80/167 (47%), Gaps = 6/167 (3%) Frame = +1 Query: 4 NILLDEDFEAV-VGDFGLAKLMDYKDTHVTTAVRGTIGHIA---PEYLSTGKSSEKTDVF 171 N+++ DFE++ + D G++ +D ++ V+ IG E L G ++K D+F Sbjct: 175 NVVIKGDFESIKICDVGVSLPLD-ENMQVSDPKAHYIGTEPWKPKEALEDGVITDKADIF 233 Query: 172 GYGIMLLELIT-GQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVD-PDLQSVYVEHE 345 YG+ L E++T ++ D+D + + ++ E L P L +V + Sbjct: 234 AYGLTLWEMMTLSVPHLEMLDTEGDEDDDDESFEEDFDEDAYYERLGSRPALDAVTLGGS 293 Query: 346 VEALIQVALLCTQGSPMDRPKMSEVVRMLEGDGLAERWEEWQKVEVV 486 + ++++ LCT+ P RP + +V++LE + + Q EV+ Sbjct: 294 YQRMVELFCLCTEEDPQKRPSAAHIVQVLESNSQLSK----QNTEVI 336
>MATK_HUMAN (P42679) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase) Length = 507 Score = 45.8 bits (107), Expect = 6e-05 Identities = 28/71 (39%), Positives = 40/71 (56%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 NIL+ ED A V DFGLAK + + R + APE L GK + K+DV+ +G+ Sbjct: 357 NILVSEDLVAKVSDFGLAKA----ERKGLDSSRLPVKWTAPEALKHGKFTSKSDVWSFGV 412 Query: 184 MLLELITGQRA 216 +L E+ + RA Sbjct: 413 LLWEVFSYGRA 423
>KPC2_CAEEL (P90980) Protein kinase C-like 2 (EC 2.7.11.13) (PKC2)| Length = 682 Score = 45.8 bits (107), Expect = 6e-05 Identities = 24/73 (32%), Positives = 38/73 (52%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 N++L+ D + DFG+ K + D T GT +IAPE + + D + YG+ Sbjct: 477 NVMLERDGHIKITDFGMCKENIFGDA-TTKTFCGTPDYIAPEIILYQPYGKSVDWWAYGV 535 Query: 184 MLLELITGQRAFD 222 +L E++ GQ FD Sbjct: 536 LLFEMLAGQPPFD 548
>NEK2_MOUSE (O35942) Serine/threonine-protein kinase Nek2 (EC 2.7.11.1)| (NimA-related protein kinase 2) Length = 443 Score = 45.4 bits (106), Expect = 8e-05 Identities = 23/66 (34%), Positives = 39/66 (59%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 AN+ LD +GDFGLA+++++ DT GT +++PE +S +EK+D++ Sbjct: 145 ANVFLDSKHNVKLGDFGLARILNH-DTSFAKTFVGTPYYMSPEQMSCLSYNEKSDIWSLA 203 Query: 181 IMLLEL 198 +L EL Sbjct: 204 CLLYEL 209
>NEK9_HUMAN (Q8TD19) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)| (NimA-related protein kinase 9) (Never in mitosis A-related kinase 9) (Nercc1 kinase) (NIMA-related kinase 8) (Nek8) Length = 979 Score = 45.4 bits (106), Expect = 8e-05 Identities = 40/140 (28%), Positives = 66/140 (47%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 NI L + +GD+GLAK ++ + + T V GT +++PE K + K+D++ G Sbjct: 181 NIFLTKANLIKLGDYGLAKKLNSEYSMAETLV-GTPYYMSPELCQGVKYNFKSDIWAVGC 239 Query: 184 MLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEALIQ 363 ++ EL+T +R FD N + + V+G+ M VD S+ LIQ Sbjct: 240 VIFELLTLKRTFDATNPLN----LCVKIVQGIR-----AMEVDSSQYSL-------ELIQ 283 Query: 364 VALLCTQGSPMDRPKMSEVV 423 + C P RP E++ Sbjct: 284 MVHSCLDQDPEQRPTADELL 303
>RIPK5_HUMAN (Q6XUX3) Receptor-interacting serine/threonine-protein kinase 5 (EC| 2.7.11.1) (Dusty protein kinase) (Dusty PK) (RIP-homologous kinase) Length = 929 Score = 45.4 bits (106), Expect = 8e-05 Identities = 43/149 (28%), Positives = 66/149 (44%), Gaps = 4/149 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 N+LLD+ A + D G K + ++ ++ GT H+APE L TGK DV+ +GI Sbjct: 782 NVLLDKQNRAKITDLGFCK----PEAMMSGSIVGTPIHMAPE-LFTGKYDNSVDVYAFGI 836 Query: 184 MLLELITGQ----RAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVE 351 + + +G AF+ R A+ D + W V P+ V+ E Sbjct: 837 LFWYICSGSVKLPEAFE--RCASKDHL----W-------NNVRRGARPERLPVFDEE--- 880 Query: 352 ALIQVALLCTQGSPMDRPKMSEVVRMLEG 438 Q+ C G P+ RP + V ML+G Sbjct: 881 -CWQLMEACWDGDPLKRPLLGIVQPMLQG 908
>RIPK5_PANTR (Q4VSN5) Receptor-interacting serine/threonine-protein kinase 5 (EC| 2.7.11.1) (Dusty protein kinase) (Dusty PK) Length = 930 Score = 45.4 bits (106), Expect = 8e-05 Identities = 43/149 (28%), Positives = 66/149 (44%), Gaps = 4/149 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 N+LLD+ A + D G K + ++ ++ GT H+APE L TGK DV+ +GI Sbjct: 783 NVLLDKQNRAKITDLGFCK----PEAMMSGSIVGTPIHMAPE-LFTGKYDNSVDVYAFGI 837 Query: 184 MLLELITGQ----RAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVE 351 + + +G AF+ R A+ D + W V P+ V+ E Sbjct: 838 LFWYICSGSVKLPEAFE--RCASKDHL----W-------NNVRRGARPERLPVFDEE--- 881 Query: 352 ALIQVALLCTQGSPMDRPKMSEVVRMLEG 438 Q+ C G P+ RP + V ML+G Sbjct: 882 -CWQLMEACWDGDPLKRPLLGIVQPMLQG 909
>FYN_MOUSE (P39688) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 45.4 bits (106), Expect = 8e-05 Identities = 25/71 (35%), Positives = 39/71 (54%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 ANIL+ + DFGLA+L++ + + I APE G+ + K+DV+ +G Sbjct: 390 ANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFG 449 Query: 181 IMLLELITGQR 213 I+L EL+T R Sbjct: 450 ILLTELVTKGR 460
>FYN_CHICK (Q05876) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 45.4 bits (106), Expect = 8e-05 Identities = 25/71 (35%), Positives = 39/71 (54%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 ANIL+ + DFGLA+L++ + + I APE G+ + K+DV+ +G Sbjct: 390 ANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFG 449 Query: 181 IMLLELITGQR 213 I+L EL+T R Sbjct: 450 ILLTELVTKGR 460
>RAF1_CHICK (P05625) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (RAF-1) (C-RAF) (MIL proto-oncogene serine/threonine-protein kinase) (C-MIL) Length = 647 Score = 45.4 bits (106), Expect = 8e-05 Identities = 38/148 (25%), Positives = 70/148 (47%), Gaps = 4/148 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMD-YKDTHVTTAVRGTIGHIAPEYLSTGKS---SEKTDVF 171 NI L E +GDFGLA + + + G+I +APE + S S ++DV+ Sbjct: 473 NIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSILWMAPEVIRMQDSNPFSFQSDVY 532 Query: 172 GYGIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVE 351 YGI+L EL+TG+ + + + N D ++ + PDL +Y ++ + Sbjct: 533 SYGIVLYELMTGELPY--SHINNRDQIIFM----------VGRGYASPDLSKLY-KNCPK 579 Query: 352 ALIQVALLCTQGSPMDRPKMSEVVRMLE 435 A+ ++ C + +RP +++ +E Sbjct: 580 AMKRLVADCLKKVREERPLFPQILSSIE 607
>POLO_DROME (P52304) Serine/threonine-protein kinase polo (EC 2.7.11.21)| Length = 576 Score = 45.4 bits (106), Expect = 8e-05 Identities = 25/77 (32%), Positives = 42/77 (54%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 N+ L++ +GDFGLA ++Y+ T + GT +IAPE L+ S + D++ G Sbjct: 153 NLFLNDLLHVKIGDFGLATRIEYEGERKKT-LCGTPNYIAPEILTKKGHSFEVDIWSIGC 211 Query: 184 MLLELITGQRAFDLARL 234 ++ L+ GQ F+ L Sbjct: 212 VMYTLLVGQPPFETKTL 228
>ARBK2_BOVIN (P26818) Beta-adrenergic receptor kinase 2 (EC 2.7.11.15)| (Beta-ARK-2) (G-protein-coupled receptor kinase 3) Length = 688 Score = 45.4 bits (106), Expect = 8e-05 Identities = 29/74 (39%), Positives = 38/74 (51%), Gaps = 1/74 (1%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKT-DVFGY 177 ANILLDE + D GLA K H + GT G++APE L G + + + D F Sbjct: 321 ANILLDEHGHVRISDLGLACDFSKKKPHASV---GTHGYMAPEVLQKGTAYDSSADWFSL 377 Query: 178 GIMLLELITGQRAF 219 G ML +L+ G F Sbjct: 378 GCMLFKLLRGHSPF 391
>KPC2_APLCA (Q16975) Calcium-independent protein kinase C (EC 2.7.11.13) (APL| II) Length = 743 Score = 45.4 bits (106), Expect = 8e-05 Identities = 30/95 (31%), Positives = 44/95 (46%), Gaps = 6/95 (6%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 NILLD + + DFG+ K + +T GT +IAPE L K D + G+ Sbjct: 532 NILLDAEGHCKIADFGMCK-EGMTENKLTQTFCGTPDYIAPEILQELKYDASVDWWALGV 590 Query: 184 MLLELITGQRAF------DLARLANDDDVMLLDWV 270 ++ E++ GQ F DL DDV+ W+ Sbjct: 591 LMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWL 625
>FYN_XENLA (P13406) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 536 Score = 45.4 bits (106), Expect = 8e-05 Identities = 25/71 (35%), Positives = 39/71 (54%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 ANIL+ + DFGLA+L++ + + I APE G+ + K+DV+ +G Sbjct: 393 ANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFG 452 Query: 181 IMLLELITGQR 213 I+L EL+T R Sbjct: 453 ILLTELVTKGR 463
>FYN_HUMAN (P06241) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) (Protooncogene Syn) (SLK) Length = 536 Score = 45.4 bits (106), Expect = 8e-05 Identities = 25/71 (35%), Positives = 39/71 (54%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 ANIL+ + DFGLA+L++ + + I APE G+ + K+DV+ +G Sbjct: 393 ANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFG 452 Query: 181 IMLLELITGQR 213 I+L EL+T R Sbjct: 453 ILLTELVTKGR 463
>BYR2_SCHPO (P28829) Protein kinase byr2 (EC 2.7.11.25) (Protein kinase ste8)| (MAPK kinase kinase) (MAPKKK) Length = 659 Score = 45.4 bits (106), Expect = 8e-05 Identities = 22/78 (28%), Positives = 44/78 (56%), Gaps = 5/78 (6%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTT-----AVRGTIGHIAPEYLSTGKSSEKTD 165 ANIL+D + + DFG++K ++ T T + +G+ +APE + +EKTD Sbjct: 526 ANILVDNKGKIKISDFGISKKLELNSTSTKTGGARPSFQGSSFWMAPEVVKQTMHTEKTD 585 Query: 166 VFGYGIMLLELITGQRAF 219 ++ G +++E++T + + Sbjct: 586 IWSLGCLVIEMLTSKHPY 603
>EPA4A_BRARE (O13148) Ephrin type-A receptor 4a (EC 2.7.10.1) (Tyrosine-protein| kinase receptor ZEK2) (EPH-like kinase 2) (Fragment) Length = 292 Score = 45.4 bits (106), Expect = 8e-05 Identities = 40/156 (25%), Positives = 76/156 (48%), Gaps = 12/156 (7%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLM--DYKDTHVTTAVRGT---------IGHIAPEYLSTGKS 150 NIL++ + V DFG+++++ D + T + GT I APE ++ K Sbjct: 125 NILVNSNLVCKVSDFGMSRVLEEDPDAAYTTREITGTYQSQGGKIPIRWTAPEAITYRKF 184 Query: 151 SEKTDVFGYGIMLLELIT-GQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQS 327 + +DV+ YGI++ E+++ G+R + D+ D +K + + ++ +D + Sbjct: 185 TSASDVWSYGIVMWEVMSYGERPYW--------DMSNQDVIKAIEEGYRLPPPMDCPV-- 234 Query: 328 VYVEHEVEALIQVALLCTQGSPMDRPKMSEVVRMLE 435 +L Q+ L C Q +RPK S++V ML+ Sbjct: 235 --------SLHQLMLDCWQKERAERPKFSQIVNMLD 262
>NEK2_HUMAN (P51955) Serine/threonine-protein kinase Nek2 (EC 2.7.11.1)| (NimA-related protein kinase 2) (NimA-like protein kinase 1) (HSPK 21) Length = 445 Score = 45.4 bits (106), Expect = 8e-05 Identities = 23/66 (34%), Positives = 41/66 (62%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 AN+ LD +GDFGLA+++++ + T V GT +++PE ++ +EK+D++ G Sbjct: 145 ANVFLDGKQNVKLGDFGLARILNHDTSFAKTFV-GTPYYMSPEQMNRMSYNEKSDIWSLG 203 Query: 181 IMLLEL 198 +L EL Sbjct: 204 CLLYEL 209
>KPK1_ARATH (P42818) Serine/threonine-protein kinase AtPK1/AtPK6 (EC 2.7.11.1)| Length = 465 Score = 45.4 bits (106), Expect = 8e-05 Identities = 24/72 (33%), Positives = 43/72 (59%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 NIL+D D ++ DFGLAK ++++ + ++ GT ++APE + + D + GI Sbjct: 262 NILMDTDGHVMLTDFGLAK--EFEENTRSNSMCGTTEYMAPEIVRGKGHDKAADWWSVGI 319 Query: 184 MLLELITGQRAF 219 +L E++TG+ F Sbjct: 320 LLYEMLTGKPPF 331
>PLO1_SCHPO (P50528) Serine/threonine-protein kinase plo1 (EC 2.7.11.21)| Length = 683 Score = 45.4 bits (106), Expect = 8e-05 Identities = 29/75 (38%), Positives = 44/75 (58%), Gaps = 3/75 (4%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAK-LMDYKDTHVTTAVRGTIGHIAPEYLSTGKS--SEKTDVFG 174 NI+LDE +GDFGLA LMD ++ +T + GT +IAPE L K S + D++ Sbjct: 168 NIMLDESNNVKIGDFGLAALLMDDEERKMT--ICGTPNYIAPEILFNSKEGHSFEVDLWS 225 Query: 175 YGIMLLELITGQRAF 219 G+++ L+ G+ F Sbjct: 226 AGVVMYALLIGKPPF 240
>KPCZ_RAT (P09217) Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)| Length = 592 Score = 45.1 bits (105), Expect = 1e-04 Identities = 32/120 (26%), Positives = 61/120 (50%), Gaps = 1/120 (0%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKL-MDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 N+LLD D + D+G+ K + DT T+ GT +IAPE L + D + G Sbjct: 381 NVLLDADGHIKLTDYGMCKEGLGPGDT--TSTFCGTPNYIAPEILRGEEYGFSVDWWALG 438 Query: 181 IMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEALI 360 +++ E++ G+ FD+ + ++ D+ D++ ++ EK + + P SV H ++ + Sbjct: 439 VLMFEMMAGRSPFDI--ITDNPDMNTEDYLFQVILEKPIRI---PRFLSVKASHVLKGFL 493
>KPCZ_MOUSE (Q02956) Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)| Length = 592 Score = 45.1 bits (105), Expect = 1e-04 Identities = 32/120 (26%), Positives = 61/120 (50%), Gaps = 1/120 (0%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKL-MDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 N+LLD D + D+G+ K + DT T+ GT +IAPE L + D + G Sbjct: 381 NVLLDADGHIKLTDYGMCKEGLGPGDT--TSTFCGTPNYIAPEILRGEEYGFSVDWWALG 438 Query: 181 IMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEALI 360 +++ E++ G+ FD+ + ++ D+ D++ ++ EK + + P SV H ++ + Sbjct: 439 VLMFEMMAGRSPFDI--ITDNPDMNTEDYLFQVILEKPIRI---PRFLSVKASHVLKGFL 493
>KPCZ_HUMAN (Q05513) Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)| Length = 592 Score = 45.1 bits (105), Expect = 1e-04 Identities = 32/120 (26%), Positives = 61/120 (50%), Gaps = 1/120 (0%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKL-MDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 N+LLD D + D+G+ K + DT T+ GT +IAPE L + D + G Sbjct: 381 NVLLDADGHIKLTDYGMCKEGLGPGDT--TSTFCGTPNYIAPEILRGEEYGFSVDWWALG 438 Query: 181 IMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEALI 360 +++ E++ G+ FD+ + ++ D+ D++ ++ EK + + P SV H ++ + Sbjct: 439 VLMFEMMAGRSPFDI--ITDNPDMNTEDYLFQVILEKPIRI---PRFLSVKASHVLKGFL 493
>KPCI_BRARE (Q90XF2) Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota)| (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (Heart and soul protein) Length = 588 Score = 45.1 bits (105), Expect = 1e-04 Identities = 25/100 (25%), Positives = 51/100 (51%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 N+LLD + + D+G+ K + T+ GT +IAPE L D + G+ Sbjct: 375 NVLLDSEGHIKLTDYGMCK-EGLRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGV 433 Query: 184 MLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEM 303 ++ E++ G+ FD+ +++ D D++ ++ EK++ + Sbjct: 434 LMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRI 473
>KS6A5_MOUSE (Q8C050) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RLSK) Length = 863 Score = 45.1 bits (105), Expect = 1e-04 Identities = 26/74 (35%), Positives = 41/74 (55%), Gaps = 2/74 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKS--SEKTDVFGY 177 NILLD + V+ DFGL+K +T + GTI ++AP+ + G S + D + Sbjct: 181 NILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIVRGGDSGHDKAVDWWSL 240 Query: 178 GIMLLELITGQRAF 219 G+++ EL+TG F Sbjct: 241 GVLMYELLTGASPF 254 Score = 35.4 bits (80), Expect = 0.081 Identities = 36/133 (27%), Positives = 61/133 (45%) Frame = +1 Query: 16 DEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGIMLLE 195 +++ E V DFG A+L + + T T+ + APE L+ E D++ G++L Sbjct: 620 NDNLEIKVIDFGFARLKPPDNQPLKTPCF-TLHYAAPELLTHNGYDESCDLWSLGVILYT 678 Query: 196 LITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEALIQVALL 375 +++GQ F ++D + V+ + K KK + + + V E + LIQ L Sbjct: 679 MLSGQVPFQ----SHDRSLTCTSAVEIMKKIKKGDFSFEGEAWK-NVSQEAKDLIQGLLT 733 Query: 376 CTQGSPMDRPKMS 414 P R KMS Sbjct: 734 V---DPNKRLKMS 743
>KPK19_ARATH (Q39030) Serine/threonine-protein kinase AtPK19 (EC 2.7.11.1)| (Ribosomal-protein S6 kinase homolog) Length = 471 Score = 45.1 bits (105), Expect = 1e-04 Identities = 24/72 (33%), Positives = 43/72 (59%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 NIL+D D ++ DFGLAK ++++ + ++ GT ++APE + + D + GI Sbjct: 268 NILMDVDGHVMLTDFGLAK--EFEENTRSNSMCGTTEYMAPEIVRGKGHDKAADWWSVGI 325 Query: 184 MLLELITGQRAF 219 +L E++TG+ F Sbjct: 326 LLYEMLTGKPPF 337
>KPCI_PONPY (Q5R4K9) Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota)| Length = 587 Score = 45.1 bits (105), Expect = 1e-04 Identities = 25/100 (25%), Positives = 51/100 (51%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 N+LLD + + D+G+ K + T+ GT +IAPE L D + G+ Sbjct: 374 NVLLDSEGHIKLTDYGMCK-EGLRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGV 432 Query: 184 MLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEM 303 ++ E++ G+ FD+ +++ D D++ ++ EK++ + Sbjct: 433 LMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRI 472
>KPCI_HUMAN (P41743) Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota)| (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (PRKC-lambda/iota) Length = 587 Score = 45.1 bits (105), Expect = 1e-04 Identities = 25/100 (25%), Positives = 51/100 (51%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 N+LLD + + D+G+ K + T+ GT +IAPE L D + G+ Sbjct: 374 NVLLDSEGHIKLTDYGMCK-EGLRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGV 432 Query: 184 MLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEM 303 ++ E++ G+ FD+ +++ D D++ ++ EK++ + Sbjct: 433 LMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRI 472
>SRC42_DROME (Q9V9J3) Tyrosine-protein kinase Src42A (EC 2.7.10.2) (Dsrc41)| Length = 517 Score = 45.1 bits (105), Expect = 1e-04 Identities = 24/67 (35%), Positives = 37/67 (55%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 N+L+ + + DFGLA+L+ + R I APE + K S K+DV+ +GI Sbjct: 375 NVLVGDGNIVKIADFGLARLIKEDEYEARVGARFPIKWTAPEAANYSKFSIKSDVWSFGI 434 Query: 184 MLLELIT 204 +L EL+T Sbjct: 435 LLTELVT 441
>RAF1_HUMAN (P04049) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 45.1 bits (105), Expect = 1e-04 Identities = 36/148 (24%), Positives = 69/148 (46%), Gaps = 4/148 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMD-YKDTHVTTAVRGTIGHIAPEYL---STGKSSEKTDVF 171 NI L E +GDFGLA + + + G++ +APE + S ++DV+ Sbjct: 473 NIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVY 532 Query: 172 GYGIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVE 351 YGI+L EL+TG+ + + + N D ++ + PDL +Y ++ + Sbjct: 533 SYGIVLYELMTGELPY--SHINNRDQIIFM----------VGRGYASPDLSKLY-KNCPK 579 Query: 352 ALIQVALLCTQGSPMDRPKMSEVVRMLE 435 A+ ++ C + +RP +++ +E Sbjct: 580 AMKRLVADCVKKVKEERPLFPQILSSIE 607
>KS6AB_XENLA (P10666) Ribosomal protein S6 kinase 2 beta (EC 2.7.11.1)| (Ribosomal protein S6 kinase II beta) (S6KII-beta) (P90-RSK) Length = 629 Score = 45.1 bits (105), Expect = 1e-04 Identities = 25/73 (34%), Positives = 43/73 (58%), Gaps = 1/73 (1%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAK-LMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 NILLDE+ + DFGL+K +D++ + GT+ ++APE ++ S D + YG Sbjct: 192 NILLDEEGHIKLTDFGLSKEAIDHEKKAYSFC--GTVEYMAPEVVNRQGHSHGADWWSYG 249 Query: 181 IMLLELITGQRAF 219 +++ E++TG F Sbjct: 250 VLMFEMLTGSLPF 262 Score = 28.9 bits (63), Expect = 7.6 Identities = 24/77 (31%), Positives = 40/77 (51%), Gaps = 4/77 (5%) Frame = +1 Query: 1 ANIL-LDE--DFEAV-VGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDV 168 +NIL +DE D E++ + DFG +K + ++ + T T +APE L E D+ Sbjct: 537 SNILYVDESGDPESIRICDFGFSKQLRAENGLLMTPCY-TANFVAPEVLKRQGYDEGCDI 595 Query: 169 FGYGIMLLELITGQRAF 219 + GI+L ++ G F Sbjct: 596 WSLGILLYTMLAGYTPF 612
>KPCZ_RABIT (O19111) Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)| Length = 591 Score = 45.1 bits (105), Expect = 1e-04 Identities = 32/120 (26%), Positives = 61/120 (50%), Gaps = 1/120 (0%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKL-MDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 N+LLD D + D+G+ K + DT T+ GT +IAPE L + D + G Sbjct: 380 NVLLDADGHIKLTDYGMCKEGLGPGDT--TSTFCGTPNYIAPEILRGEEYGFSVDWWALG 437 Query: 181 IMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEALI 360 +++ E++ G+ FD+ + ++ D+ D++ ++ EK + + P SV H ++ + Sbjct: 438 VLMFEMMAGRSPFDI--ITDNPDMNTEDYLFQVILEKPIRI---PRFLSVKASHVLKGFL 492
>EPHA3_HUMAN (P29320) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4) Length = 983 Score = 45.1 bits (105), Expect = 1e-04 Identities = 38/147 (25%), Positives = 73/147 (49%), Gaps = 3/147 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLM--DYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGY 177 NIL++ + V DFGL++++ D + + T + I +PE ++ K + +DV+ Y Sbjct: 751 NILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTSPEAIAYRKFTSASDVWSY 810 Query: 178 GIMLLELIT-GQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEA 354 GI+L E+++ G+R + ++N D + +D +G ++ A Sbjct: 811 GIVLWEVMSYGERPY--WEMSNQDVIKAVD--EGYRLPPPMDCPA--------------A 852 Query: 355 LIQVALLCTQGSPMDRPKMSEVVRMLE 435 L Q+ L C Q +RPK ++V +L+ Sbjct: 853 LYQLMLDCWQKDRNNRPKFEQIVSILD 879
>ARBK1_RAT (P26817) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein-coupled receptor kinase 2) Length = 689 Score = 45.1 bits (105), Expect = 1e-04 Identities = 29/74 (39%), Positives = 38/74 (51%), Gaps = 1/74 (1%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKT-DVFGY 177 ANILLDE + D GLA K H + GT G++APE L G + + + D F Sbjct: 321 ANILLDEHGHVRISDLGLACDFSKKKPHASV---GTHGYMAPEVLQKGVAYDSSADWFSL 377 Query: 178 GIMLLELITGQRAF 219 G ML +L+ G F Sbjct: 378 GCMLFKLLRGHSPF 391
>ARBK1_MESAU (Q64682) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein-coupled receptor kinase 2) Length = 689 Score = 45.1 bits (105), Expect = 1e-04 Identities = 29/74 (39%), Positives = 38/74 (51%), Gaps = 1/74 (1%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKT-DVFGY 177 ANILLDE + D GLA K H + GT G++APE L G + + + D F Sbjct: 321 ANILLDEHGHVRISDLGLACDFSKKKPHASV---GTHGYMAPEVLQKGVAYDSSADWFSL 377 Query: 178 GIMLLELITGQRAF 219 G ML +L+ G F Sbjct: 378 GCMLFKLLRGHSPF 391
>ARBK1_HUMAN (P25098) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein coupled receptor kinase 2) Length = 689 Score = 45.1 bits (105), Expect = 1e-04 Identities = 29/74 (39%), Positives = 38/74 (51%), Gaps = 1/74 (1%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKT-DVFGY 177 ANILLDE + D GLA K H + GT G++APE L G + + + D F Sbjct: 321 ANILLDEHGHVRISDLGLACDFSKKKPHASV---GTHGYMAPEVLQKGVAYDSSADWFSL 377 Query: 178 GIMLLELITGQRAF 219 G ML +L+ G F Sbjct: 378 GCMLFKLLRGHSPF 391
>ARBK1_BOVIN (P21146) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein-coupled receptor kinase 2) Length = 689 Score = 45.1 bits (105), Expect = 1e-04 Identities = 29/74 (39%), Positives = 38/74 (51%), Gaps = 1/74 (1%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKT-DVFGY 177 ANILLDE + D GLA K H + GT G++APE L G + + + D F Sbjct: 321 ANILLDEHGHVRISDLGLACDFSKKKPHASV---GTHGYMAPEVLQKGVAYDSSADWFSL 377 Query: 178 GIMLLELITGQRAF 219 G ML +L+ G F Sbjct: 378 GCMLFKLLRGHSPF 391
>TESK1_RAT (Q63572) Dual specificity testis-specific protein kinase 1 (EC| 2.7.12.1) (Testicular protein kinase 1) Length = 628 Score = 45.1 bits (105), Expect = 1e-04 Identities = 31/65 (47%), Positives = 38/65 (58%), Gaps = 3/65 (4%) Frame = +1 Query: 16 DEDFEAVVGDFGLA-KLMDYKD--THVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGIM 186 D F AVVGDFGLA K+ Y++ AV G+ +APE L EK DVF +GI+ Sbjct: 182 DGGFTAVVGDFGLAEKIPVYREGARKEPLAVVGSPYWMAPEVLRGELYDEKADVFAFGIV 241 Query: 187 LLELI 201 L ELI Sbjct: 242 LCELI 246
>KS6A5_HUMAN (O75582) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RSKL) Length = 802 Score = 45.1 bits (105), Expect = 1e-04 Identities = 26/74 (35%), Positives = 41/74 (55%), Gaps = 2/74 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKS--SEKTDVFGY 177 NILLD + V+ DFGL+K +T + GTI ++AP+ + G S + D + Sbjct: 182 NILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIVRGGDSGHDKAVDWWSL 241 Query: 178 GIMLLELITGQRAF 219 G+++ EL+TG F Sbjct: 242 GVLMYELLTGASPF 255 Score = 35.4 bits (80), Expect = 0.081 Identities = 35/133 (26%), Positives = 61/133 (45%) Frame = +1 Query: 16 DEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGIMLLE 195 +++ E + DFG A+L + + T T+ + APE L+ E D++ G++L Sbjct: 556 NDNLEIKIIDFGFARLKPPDNQPLKTPCF-TLHYAAPELLNQNGYDESCDLWSLGVILYT 614 Query: 196 LITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVEALIQVALL 375 +++GQ F ++D + V+ + K KK + + + V E + LIQ L Sbjct: 615 MLSGQVPFQ----SHDRSLTCTSAVEIMKKIKKGDFSFEGEAWK-NVSQEAKDLIQGLLT 669 Query: 376 CTQGSPMDRPKMS 414 P R KMS Sbjct: 670 V---DPNKRLKMS 679
>ANKK1_HUMAN (Q8NFD2) Ankyrin repeat and protein kinase domain-containing| protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288) Length = 765 Score = 45.1 bits (105), Expect = 1e-04 Identities = 27/78 (34%), Positives = 48/78 (61%), Gaps = 6/78 (7%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHV----TTAVRGTIGHIAPE-YLSTGKS-SEKTD 165 NILLD + + DFGL+K M+ + T + +A+RG + +I PE +L + K+ K D Sbjct: 150 NILLDSNMHVKISDFGLSKWME-QSTRMQYIERSALRGMLSYIPPEMFLESNKAPGPKYD 208 Query: 166 VFGYGIMLLELITGQRAF 219 V+ + I++ EL+T ++ + Sbjct: 209 VYSFAIVIWELLTQKKPY 226
>KS6A2_HUMAN (Q15349) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (MAP kinase-activated protein kinase 1c) (MAPKAPK1C) Length = 733 Score = 45.1 bits (105), Expect = 1e-04 Identities = 24/72 (33%), Positives = 41/72 (56%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 NILLDE+ + DFGL+K D + GTI ++APE ++ ++ D + +G+ Sbjct: 189 NILLDEEGHIKITDFGLSKEAIDHDKRAYSFC-GTIEYMAPEVVNRRGHTQSADWWSFGV 247 Query: 184 MLLELITGQRAF 219 ++ E++TG F Sbjct: 248 LMFEMLTGSLPF 259
>GRK1_CAEEL (Q09537) G protein-coupled receptor kinase 1 (EC 2.7.11.16)| Length = 642 Score = 45.1 bits (105), Expect = 1e-04 Identities = 25/72 (34%), Positives = 39/72 (54%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 NILLD+ + D GLA ++ KD GT+G++APE + + S D +G G Sbjct: 333 NILLDDFGHVRISDLGLA--VEIKDNEPIKGRVGTVGYMAPEIVKNERYSYGVDWWGVGC 390 Query: 184 MLLELITGQRAF 219 ++ E+I G+ F Sbjct: 391 LIYEMIEGKAPF 402
>PKN2_CLOAB (Q97IC2) Probable serine/threonine protein kinase CAC1728 (EC| 2.7.11.1) Length = 657 Score = 45.1 bits (105), Expect = 1e-04 Identities = 23/73 (31%), Positives = 40/73 (54%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 NI++ +D V DFG+AK + T V G+ +++PE +TD++ +GI Sbjct: 138 NIMVTDDDIIKVTDFGIAKASNESTITTTNKVVGSAHYLSPEQAQGIPVDCRTDIYSFGI 197 Query: 184 MLLELITGQRAFD 222 +L E+ TG+ +D Sbjct: 198 VLYEMATGKVPYD 210
>RIPK1_MOUSE (Q60855) Receptor-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein) Length = 656 Score = 45.1 bits (105), Expect = 1e-04 Identities = 38/149 (25%), Positives = 70/149 (46%), Gaps = 15/149 (10%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLA---------KLMDYKDTHVTTAVR----GTIGHIAPEYLS-- 138 NIL+D DF + D G+A K D K V++ + GT+ ++APE+L+ Sbjct: 143 NILVDRDFHIKIADLGVASFKTWSKLTKEKDNKQKEVSSTTKKNNGGTLYYMAPEHLNDI 202 Query: 139 TGKSSEKTDVFGYGIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPD 318 K +EK+DV+ +GI+L + + + ++V+ + +K P+ Sbjct: 203 NAKPTEKSDVYSFGIVLWAIFAKKEPY--------ENVICTEQFVICIKSGN-----RPN 249 Query: 319 LQSVYVEHEVEALIQVALLCTQGSPMDRP 405 ++ + +E+ +I + C Q P DRP Sbjct: 250 VEEI-LEYCPREIISLMERCWQAIPEDRP 277
>KPCI_MOUSE (Q62074) Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota)| (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) Length = 586 Score = 45.1 bits (105), Expect = 1e-04 Identities = 25/100 (25%), Positives = 51/100 (51%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 N+LLD + + D+G+ K + T+ GT +IAPE L D + G+ Sbjct: 373 NVLLDSEGHIKLTDYGMCK-EGLRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGV 431 Query: 184 MLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEM 303 ++ E++ G+ FD+ +++ D D++ ++ EK++ + Sbjct: 432 LMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRI 471
>RIPK5_CANFA (Q4VSN4) Receptor-interacting serine/threonine-protein kinase 5 (EC| 2.7.11.1) (Dusty protein kinase) (Dusty PK) Length = 931 Score = 44.7 bits (104), Expect = 1e-04 Identities = 43/149 (28%), Positives = 65/149 (43%), Gaps = 4/149 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 N+LLD+ A + D G K + ++ ++ GT H+APE L TGK DV+ +GI Sbjct: 784 NVLLDKQNRAKITDLGFCK----PEAMMSGSIVGTPIHMAPE-LFTGKYDNSVDVYAFGI 838 Query: 184 MLLELITGQ----RAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVE 351 + + +G AF+ R A+ D + W V P+ V+ E Sbjct: 839 LFWYICSGSVKLPEAFE--RCASKDHL----W-------NNVRRGARPERLPVFDEE--- 882 Query: 352 ALIQVALLCTQGSPMDRPKMSEVVRMLEG 438 Q+ C G P RP + V ML+G Sbjct: 883 -CWQLMEACWDGDPSQRPLLGIVQPMLQG 910
>RAF1_RAT (P11345) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 44.7 bits (104), Expect = 1e-04 Identities = 36/148 (24%), Positives = 69/148 (46%), Gaps = 4/148 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMD-YKDTHVTTAVRGTIGHIAPEYL---STGKSSEKTDVF 171 NI L E +GDFGLA + + + G++ +APE + S ++DV+ Sbjct: 473 NIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVY 532 Query: 172 GYGIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVE 351 YGI+L EL+TG+ + + + N D ++ + PDL +Y ++ + Sbjct: 533 SYGIVLYELMTGELPY--SHINNRDQIIFM----------VGRGYASPDLSRLY-KNCPK 579 Query: 352 ALIQVALLCTQGSPMDRPKMSEVVRMLE 435 A+ ++ C + +RP +++ +E Sbjct: 580 AMKRLVADCVKKVKEERPLFPQILSSIE 607
>YES_CANFA (Q28923) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 538 Score = 44.7 bits (104), Expect = 1e-04 Identities = 25/71 (35%), Positives = 39/71 (54%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 ANIL+ E+ + DFGLA+L++ + + I APE G+ + K+DV+ +G Sbjct: 395 ANILVGENLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFG 454 Query: 181 IMLLELITGQR 213 I+ EL T R Sbjct: 455 ILQTELTTKGR 465
>PLK1_CAEEL (P34331) Serine/threonine-protein kinase plk-1 (EC 2.7.11.21)| (Polo-like kinase 1) Length = 649 Score = 44.7 bits (104), Expect = 1e-04 Identities = 25/73 (34%), Positives = 40/73 (54%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 N+ L++D +GDFGLA ++ + T GT +IAPE L+ S + D++ G Sbjct: 167 NLFLNDDLVVKIGDFGLATTVNGDERKKTLC--GTPNYIAPEVLNKAGHSFEVDIWAVGC 224 Query: 184 MLLELITGQRAFD 222 +L L+ GQ F+ Sbjct: 225 ILYILLFGQPPFE 237
>ARBK1_MOUSE (Q99MK8) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein-coupled receptor kinase 2) Length = 689 Score = 44.7 bits (104), Expect = 1e-04 Identities = 29/74 (39%), Positives = 38/74 (51%), Gaps = 1/74 (1%) Frame = +1 Query: 1 ANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKT-DVFGY 177 ANILLDE + D GLA K H + GT G++APE L G + + + D F Sbjct: 321 ANILLDEHGHVRISDLGLACDFSKKRPHASV---GTHGYMAPEVLQKGVAYDSSADWFSL 377 Query: 178 GIMLLELITGQRAF 219 G ML +L+ G F Sbjct: 378 GCMLFKLLRGHSPF 391
>CLA4_CANAL (O14427) Serine/threonine-protein kinase CLA4 (EC 2.7.11.1)| Length = 971 Score = 44.7 bits (104), Expect = 1e-04 Identities = 35/104 (33%), Positives = 52/104 (50%), Gaps = 3/104 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGL-AKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 180 N+LLD + DFG AKL D ++ T GT +APE + + EK DV+ G Sbjct: 808 NVLLDAYGNVKITDFGFCAKLTDQRNKRATMV--GTPYWMAPEVVKQKEYDEKVDVWSLG 865 Query: 181 IMLLELITGQRAFDLARLANDDDVMLLDWV--KGLLKEKKVEML 306 IM +E+I G+ + N++ + L + G K KK E+L Sbjct: 866 IMTIEMIEGEPPY-----LNEEPLKALYLIATNGTPKLKKPELL 904
>RIPK5_BOVIN (Q4TVR5) Receptor-interacting serine/threonine-protein kinase 5 (EC| 2.7.11.1) (Dusty protein kinase) (Dusty PK) Length = 928 Score = 44.7 bits (104), Expect = 1e-04 Identities = 43/149 (28%), Positives = 65/149 (43%), Gaps = 4/149 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 183 N+LLD+ A + D G K + ++ ++ GT H+APE L TGK DV+ +GI Sbjct: 781 NVLLDKQNRAKITDLGFCK----PEAMMSGSIVGTPIHMAPE-LFTGKYDNSVDVYAFGI 835 Query: 184 MLLELITGQ----RAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSVYVEHEVE 351 + + +G AF+ R A+ D + W V P+ V+ E Sbjct: 836 LFWYICSGSVKLPEAFE--RCASKDHL----W-------NNVRRGARPERLPVFDEE--- 879 Query: 352 ALIQVALLCTQGSPMDRPKMSEVVRMLEG 438 Q+ C G P RP + V ML+G Sbjct: 880 -CWQLMEACWDGDPSQRPLLGIVQPMLQG 907
>JAK3_RAT (Q63272) Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3)| (JAK-3) Length = 1100 Score = 44.7 bits (104), Expect = 1e-04 Identities = 26/69 (37%), Positives = 38/69 (55%), Gaps = 2/69 (2%) Frame = +1 Query: 4 NILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGT--IGHIAPEYLSTGKSSEKTDVFGY 177 NIL++ + + DFGLAKL+ + V G I APE LS S ++DV+ + Sbjct: 950 NILVESEAHVKIADFGLAKLLPLGKDYYVVRVPGQSPIFWYAPESLSDNIFSRQSDVWSF 1009 Query: 178 GIMLLELIT 204 G++L EL T Sbjct: 1010 GVVLYELFT 1018 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 52,613,006 Number of Sequences: 219361 Number of extensions: 922779 Number of successful extensions: 5386 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 4751 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4952 length of database: 80,573,946 effective HSP length: 103 effective length of database: 57,979,763 effective search space used: 3362826254 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
