ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | baal30o15 |
|---|---|
| Clone Library Name | barley_pub |
>CPK15_ARATH (P92937) CBL-interacting serine/threonine-protein kinase 15 (EC| 2.7.11.1) (Serine/threonine-protein kinase ATPK10) (SOS2-like protein kinase PKS3) (SOS-interacting protein 2) (SNF1-related kinase 3.1) Length = 421 Score = 246 bits (628), Expect = 5e-65 Identities = 123/217 (56%), Positives = 162/217 (74%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+DEHGNLK+SDFGLSAL + ++QDGLLHTTCGTPAYVAPE+I++ GYDG KAD+WSC Sbjct: 139 NLLLDEHGNLKISDFGLSALSDSRRQDGLLHTTCGTPAYVAPEVISRNGYDGFKADVWSC 198 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 GVILFVLLAGYLPF+DSNLME+Y+KI K +V++P W + A++LL R+LDPNPNTR++ + Sbjct: 199 GVILFVLLAGYLPFRDSNLMELYKKIGKAEVKFPNWLAPGAKRLLKRILDPNPNTRVSTE 258 Query: 377 KLIEHPWFKKGYKPAVMLGTPRASKDLNDVQAAFSTDHKDGEGSRAEQPNSPLKPASLNA 556 K+++ WF+KG + V + ++ +V A + EG+ A + +LNA Sbjct: 259 KIMKSSWFRKGLQEEV----KESVEEETEVDA-------EAEGN-ASAEKEKKRCINLNA 306 Query: 557 FDIISLSKGFDLSGLFEKDQEQKSNSRFMTQKPASAI 667 F+IISLS GFDLSGLFEK E+K RF + + AS I Sbjct: 307 FEIISLSTGFDLSGLFEKG-EEKEEMRFTSNREASEI 342
>CIPK1_ORYSA (Q6X4A2) CIPK-like protein 1 (EC 2.7.11.1) (OsCK1)| Length = 449 Score = 239 bits (610), Expect = 6e-63 Identities = 118/219 (53%), Positives = 153/219 (69%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D GNLKVSDFGLSAL E K DGLLHTTCGTP YVAPE+I +GYDG ADIWSC Sbjct: 148 NLLLDASGNLKVSDFGLSALTEQVKADGLLHTTCGTPNYVAPEVIEDRGYDGAAADIWSC 207 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 GVIL+VLLAG+LPF+D N++ +Y+KIS+ P WFS+ A+KL+ R+LDPNP TRIT+ Sbjct: 208 GVILYVLLAGFLPFEDDNIIALYKKISEAQFTCPSWFSTGAKKLITRILDPNPTTRITIS 267 Query: 377 KLIEHPWFKKGYKPAVMLGTPRASKDLNDVQAAFSTDHKDGEGSRAEQPNSPLKPASLNA 556 +++E PWFKKGYKP V + +DV AAF D E ++ +P S+NA Sbjct: 268 QILEDPWFKKGYKPPVF--DEKYETSFDDVDAAFG----DSEDRHVKEETED-QPTSMNA 320 Query: 557 FDIISLSKGFDLSGLFEKDQEQKSNSRFMTQKPASAIVS 673 F++ISL++ +L LFE +E K +RF +Q P I++ Sbjct: 321 FELISLNQALNLDNLFEAKKEYKRETRFTSQCPPKEIIT 359
>CPK11_ARATH (O22932) CBL-interacting serine/threonine-protein kinase 11 (EC| 2.7.11.1) (SOS2-like protein kinase PKS5) (SOS-interacting protein 4) (SNF1-related kinase 3.22) Length = 435 Score = 215 bits (548), Expect = 9e-56 Identities = 111/213 (52%), Positives = 143/213 (67%), Gaps = 1/213 (0%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+DE+GNLKVSDFGLSAL + + DGLLHT CGTPAYVAPEI++KKGY+G K D+WSC Sbjct: 150 NLLIDENGNLKVSDFGLSALTDQIRPDGLLHTLCGTPAYVAPEILSKKGYEGAKVDVWSC 209 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 G++LFVL+AGYLPF D N+M MY+KI KG+ R+P+W S D ++ + RLLD NP TRIT+D Sbjct: 210 GIVLFVLVAGYLPFNDPNVMNMYKKIYKGEYRFPRWMSPDLKRFVSRLLDINPETRITID 269 Query: 377 KLIEHPWFKKGYKPAVMLGTPRASKDLNDVQAAFSTDHKDGEGSRAEQPNSPLKPASLNA 556 ++++ PWF +G Q F D + E + E +K SLNA Sbjct: 270 EILKDPWFVRG----------------GFKQIKFHDD--EIEDQKVESSLEAVK--SLNA 309 Query: 557 FDIISLSKGFDLSGLFEKDQEQKSNS-RFMTQK 652 FD+IS S G DLSGLF S RF+++K Sbjct: 310 FDLISYSSGLDLSGLFAGCSNSSGESERFLSEK 342
>CPK24_ARATH (Q9LDI3) CBL-interacting serine/threonine-protein kinase 24 (EC| 2.7.11.1) (SNF1-related kinase 3.11) (SALT OVERLY SENSITIVE 2 protein) Length = 446 Score = 194 bits (493), Expect = 2e-49 Identities = 102/220 (46%), Positives = 148/220 (67%), Gaps = 1/220 (0%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D +GNLKVSDFGLSAL Q+ LL TTCGTP YVAPE+++ +GYDG ADIWSC Sbjct: 139 NLLLDTNGNLKVSDFGLSALP--QEGVELLRTTCGTPNYVAPEVLSGQGYDGSAADIWSC 196 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 GVILFV+LAGYLPF +++L +YRKI+ + P WFS++ + L+ R+LDPNP TRI + Sbjct: 197 GVILFVILAGYLPFSETDLPGLYRKINAAEFSCPPWFSAEVKFLIHRILDPNPKTRIQIQ 256 Query: 377 KLIEHPWFKKGYKPAVMLGTPRASKDLNDVQAAFSTDHKDGEGSRAEQPNSPLKPASLNA 556 + + PWF+ Y P + +L+D++A F D +G + P +NA Sbjct: 257 GIKKDPWFRLNYVP--IRAREEEEVNLDDIRAVF--DGIEGSYVAENVERNDEGPLMMNA 312 Query: 557 FDIISLSKGFDLSGLFEKDQE-QKSNSRFMTQKPASAIVS 673 F++I+LS+G +LS LF++ Q+ K +RF++++ S I++ Sbjct: 313 FEMITLSQGLNLSALFDRRQDFVKRQTRFVSRREPSEIIA 352
>CIPK1_ARATH (Q8RWC9) CBL-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (SOS2-like protein kinase PKS13) (SNF1-related kinase 3.16) Length = 444 Score = 188 bits (477), Expect = 1e-47 Identities = 96/218 (44%), Positives = 132/218 (60%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 N+L+D G++K++DFGLSAL + + DGLLHTTCG+P YVAPE++ +GYDG +DIWSC Sbjct: 148 NVLLDAKGHIKITDFGLSALPQHFRDDGLLHTTCGSPNYVAPEVLANRGYDGAASDIWSC 207 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 GVIL+V+L G LPF D NL +Y+KI KGD P+W S AR ++ R+LDPNP TRIT+ Sbjct: 208 GVILYVILTGCLPFDDRNLAVLYQKICKGDPPIPRWLSPGARTMIKRMLDPNPVTRITVV 267 Query: 377 KLIEHPWFKKGYKPAVMLGTPRASKDLNDVQAAFSTDHKDGEGSRAEQPNSPLKPASLNA 556 + WFK Y P++ D +D AFS E + P +NA Sbjct: 268 GIKASEWFKLEYIPSIPDDDDEEEVDTDD--DAFSIQELGSEEGKGSD-----SPTIINA 320 Query: 557 FDIISLSKGFDLSGLFEKDQEQKSNSRFMTQKPASAIV 670 F +I +S DLSG FE++ + RF + A ++ Sbjct: 321 FQLIGMSSFLDLSGFFEQENVSERRIRFTSNSSAKDLL 358
>BRSK1_HUMAN (Q8TDC3) BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1| kinase) (SAD1A) Length = 794 Score = 129 bits (324), Expect = 8e-30 Identities = 56/131 (42%), Positives = 87/131 (66%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+DE N++++DFG+++L Q D LL T+CG+P Y PE+I + YDG +AD+WSC Sbjct: 177 NLLLDEKNNIRIADFGMASL---QVGDSLLETSCGSPHYACPEVIKGEKYDGRRADMWSC 233 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 GVILF LL G LPF D NL ++ K+ +G P + D + LL +++ P R++++ Sbjct: 234 GVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVEPEKRLSLE 293 Query: 377 KLIEHPWFKKG 409 ++ +HPW+ G Sbjct: 294 QIQKHPWYLGG 304
>MELK_HUMAN (Q14680) Maternal embryonic leucine zipper kinase (EC 2.7.11.1)| (hMELK) (Protein kinase PK38) (hPK38) Length = 651 Score = 127 bits (319), Expect = 3e-29 Identities = 61/132 (46%), Positives = 85/132 (64%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL DE+ LK+ DFGL A + K D L T CG+ AY APE+I K Y G +AD+WS Sbjct: 137 NLLFDEYHKLKLIDFGLCAKPKGNK-DYHLQTCCGSLAYAAPELIQGKSYLGSEADVWSM 195 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 G++L+VL+ G+LPF D N+M +Y+KI +G P+W S + LL ++L +P RI+M Sbjct: 196 GILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMK 255 Query: 377 KLIEHPWFKKGY 412 L+ HPW + Y Sbjct: 256 NLLNHPWIMQDY 267
>MELK_MOUSE (Q61846) Maternal embryonic leucine zipper kinase (EC 2.7.11.1)| (Protein kinase PK38) (mPK38) Length = 643 Score = 127 bits (318), Expect = 4e-29 Identities = 61/132 (46%), Positives = 85/132 (64%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL DE+ LK+ DFGL A + K D L T CG+ AY APE+I K Y G +AD+WS Sbjct: 137 NLLFDENHKLKLIDFGLCAKPKGNK-DYHLQTCCGSLAYAAPELIQGKSYLGSEADVWSM 195 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 G++L+VL+ G+LPF D N+M +Y+KI +G P+W S + LL ++L +P RI+M Sbjct: 196 GILLYVLMCGFLPFDDDNVMALYKKIMRGKYEVPKWLSPSSILLLQQMLQVDPKKRISMR 255 Query: 377 KLIEHPWFKKGY 412 L+ HPW + Y Sbjct: 256 NLLNHPWVMQDY 267
>CDR2_SCHPO (P87050) Mitosis inducer protein kinase cdr2 (EC 2.7.11.1)| Length = 775 Score = 124 bits (311), Expect = 3e-28 Identities = 58/138 (42%), Positives = 89/138 (64%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NL +D HG++K+ +FG++++++ K LL T+CG+P Y +PEII + YDG +DIWSC Sbjct: 138 NLYLDAHGSIKIGEFGMASIQQPGK---LLQTSCGSPHYASPEIIMGRSYDGCASDIWSC 194 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 G+I F LL G LPF D N+ + K+ +G P S A+ LL R+LD + +TRITM+ Sbjct: 195 GIIFFALLTGKLPFDDDNIRSLLLKVCQGQFEMPSNISPQAQHLLYRMLDVDSSTRITME 254 Query: 377 KLIEHPWFKKGYKPAVML 430 ++ EHP+ P + + Sbjct: 255 QIREHPFLSCFVHPNISI 272
>BRSK2_HUMAN (Q8IWQ3) BR serine/threonine-protein kinase 2 (EC 2.7.11.1)| (Serine/threonine-protein kinase 29) (SAD1B) Length = 736 Score = 122 bits (307), Expect = 8e-28 Identities = 56/131 (42%), Positives = 84/131 (64%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+DE N++++DFG+++L Q D LL T+CG+P Y PE+I + YDG KAD+WSC Sbjct: 146 NLLLDEKNNIRIADFGMASL---QVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSC 202 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 GVILF LL G LPF D NL ++ K+ +G P + D + LL + + + R+T++ Sbjct: 203 GVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMSEVDAARRLTLE 262 Query: 377 KLIEHPWFKKG 409 + +H W+ G Sbjct: 263 HIQKHIWYIGG 273
>KIN1_SCHPO (P22987) Protein kinase kin1 (EC 2.7.11.1)| Length = 891 Score = 121 bits (303), Expect = 2e-27 Identities = 54/133 (40%), Positives = 87/133 (65%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 N+L+ + G++K+ DFGLS L Q + L T CG+ + APE++N + Y G + D+WS Sbjct: 271 NILISKTGDIKIIDFGLSNLYRRQSR---LRTFCGSLYFAAPELLNAQPYIGPEVDVWSF 327 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 G++L+VL+ G +PF D N+ ++ KI KG V YP + SSD + LL R+L +P R T++ Sbjct: 328 GIVLYVLVCGKVPFDDQNMSALHAKIKKGTVEYPSYLSSDCKGLLSRMLVTDPLKRATLE 387 Query: 377 KLIEHPWFKKGYK 415 +++ HPW + Y+ Sbjct: 388 EVLNHPWMIRNYE 400
>KIN11_ARATH (P92958) SNF1-related protein kinase catalytic alpha subunit KIN11| (EC 2.7.11.1) (AKIN11) (AKIN alpha1) Length = 512 Score = 120 bits (301), Expect = 4e-27 Identities = 60/130 (46%), Positives = 86/130 (66%), Gaps = 1/130 (0%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDG-LLHTTCGTPAYVAPEIINKKGYDGEKADIWS 193 NLL+D N+K++DFGLS + +DG L T+CG+P Y APE+I+ K Y G + D+WS Sbjct: 148 NLLLDSRCNIKIADFGLSNVM----RDGHFLKTSCGSPNYAAPEVISGKLYAGPEVDVWS 203 Query: 194 CGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITM 373 CGVIL+ LL G LPF D N+ +++KI G P SS+AR L+ R+L +P RIT+ Sbjct: 204 CGVILYALLCGTLPFDDENIPNLFKKIKGGIYTLPSHLSSEARDLIPRMLIVDPVKRITI 263 Query: 374 DKLIEHPWFK 403 ++ +H WF+ Sbjct: 264 PEIRQHRWFQ 273
>KIN10_ARATH (Q38997) SNF1-related protein kinase catalytic alpha subunit KIN10| (EC 2.7.11.1) (AKIN10) (AKIN alpha2) Length = 535 Score = 120 bits (301), Expect = 4e-27 Identities = 59/130 (45%), Positives = 85/130 (65%), Gaps = 1/130 (0%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDG-LLHTTCGTPAYVAPEIINKKGYDGEKADIWS 193 NLL+D N+K++DFGLS + +DG L T+CG+P Y APE+I+ K Y G + D+WS Sbjct: 170 NLLLDSKCNVKIADFGLSNIM----RDGHFLKTSCGSPNYAAPEVISGKLYAGPEVDVWS 225 Query: 194 CGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITM 373 CGVIL+ LL G LPF D N+ +++KI G P S AR L+ R+L +P R+T+ Sbjct: 226 CGVILYALLCGTLPFDDENIPNLFKKIKGGIYTLPSHLSPGARDLIPRMLVVDPMKRVTI 285 Query: 374 DKLIEHPWFK 403 ++ +HPWF+ Sbjct: 286 PEIRQHPWFQ 295
>SNF1_YEAST (P06782) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 633 Score = 119 bits (298), Expect = 8e-27 Identities = 70/218 (32%), Positives = 117/218 (53%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+DEH N+K++DFGLS + L T+CG+P Y APE+I+ K Y G + D+WSC Sbjct: 182 NLLLDEHLNVKIADFGLSNI---MTDGNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSC 238 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 GVIL+V+L LPF D ++ +++ IS G P++ S A L+ R+L NP RI++ Sbjct: 239 GVILYVMLCRRLPFDDESIPVLFKNISNGVYTLPKFLSPGAAGLIKRMLIVNPLNRISIH 298 Query: 377 KLIEHPWFKKGYKPAVMLGTPRASKDLNDVQAAFSTDHKDGEGSRAEQPNSPLKPASLNA 556 ++++ WFK P +L P K + + + KDG ++ + N Sbjct: 299 EIMQDDWFKVDL-PEYLL--PPDLKPHPEEENENNDSKKDGSSPDNDEIDD-------NL 348 Query: 557 FDIISLSKGFDLSGLFEKDQEQKSNSRFMTQKPASAIV 670 +I+S + G++ ++E + + F + A ++ Sbjct: 349 VNILSSTMGYEKDEIYESLESSEDTPAFNEIRDAYMLI 386
>SNF1_CANTR (O94168) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 619 Score = 118 bits (296), Expect = 1e-26 Identities = 58/130 (44%), Positives = 84/130 (64%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D+ N+K++DFGLS + L T+CG+P Y APE+I+ K Y G + D+WS Sbjct: 179 NLLLDDQLNVKIADFGLSNI---MTDGNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSS 235 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 GVIL+V+L G LPF D + +++KIS G P + S A+ LL R+L NP RIT+ Sbjct: 236 GVILYVMLCGRLPFDDEFIPALFKKISNGVYTLPNYLSPGAKHLLTRMLVVNPLNRITIH 295 Query: 377 KLIEHPWFKK 406 +++E WFK+ Sbjct: 296 EIMEDEWFKQ 305
>KKK1_YEAST (P34244) Probable serine/threonine-protein kinase YKL101W (EC| 2.7.11.1) Length = 1518 Score = 117 bits (294), Expect = 2e-26 Identities = 65/176 (36%), Positives = 100/176 (56%), Gaps = 14/176 (7%) Frame = +2 Query: 17 NLLVDEHGN-LKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWS 193 NLL+D+ +K++DFG++AL+ K LL T+CG+P Y +PEI+ + Y G +D+WS Sbjct: 244 NLLLDKKNRRIKIADFGMAALELPNK---LLKTSCGSPHYASPEIVMGRPYHGGPSDVWS 300 Query: 194 CGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITM 373 CG++LF LL G+LPF D N+ ++ K+ G + P SS+AR L+ ++L +P RIT Sbjct: 301 CGIVLFALLTGHLPFNDDNIKKLLLKVQSGKYQMPSNLSSEARDLISKILVIDPEKRITT 360 Query: 374 DKLIEHPWFKKGYKPAVMLGTPRASKD-------------LNDVQAAFSTDHKDGE 502 ++++HP KK V + KD LN+V + T H GE Sbjct: 361 QEILKHPLIKKYDDLPVNKVLRKMRKDNMARGKSNSDLHLLNNVSPSIVTLHSKGE 416
>KIN2_YEAST (P13186) Serine/threonine-protein kinase KIN2 (EC 2.7.11.1)| Length = 1147 Score = 117 bits (293), Expect = 3e-26 Identities = 53/132 (40%), Positives = 82/132 (62%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 N+++ G +K+ DFGLS + + +KQ LHT CG+ + APE++ + Y G + DIWS Sbjct: 253 NIMISSSGEIKIIDFGLSNIFDYRKQ---LHTFCGSLYFAAPELLKAQPYTGPEVDIWSF 309 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 G++L+VL+ G +PF D N ++ KI KG V YP S + LL R++ +P R T+ Sbjct: 310 GIVLYVLVCGKVPFDDENSSILHEKIKKGKVDYPSHLSIEVISLLTRMIVVDPLRRATLK 369 Query: 377 KLIEHPWFKKGY 412 ++EHPW +GY Sbjct: 370 NVVEHPWMNRGY 381
>SNF1_CANGA (Q00372) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 612 Score = 117 bits (292), Expect = 4e-26 Identities = 56/129 (43%), Positives = 84/129 (65%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+DEH N+K++DFGLS + L T+CG+P Y APE+I+ K Y G + D+WSC Sbjct: 166 NLLLDEHLNVKIADFGLSNI---MTDGNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSC 222 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 GVIL+V+L LPF D ++ +++ IS G P++ S A L+ R+L NP RI++ Sbjct: 223 GVILYVMLCRRLPFDDESIPVLFKNISNGVYTLPKFLSPGASDLIKRMLIVNPLNRISIH 282 Query: 377 KLIEHPWFK 403 ++++ WFK Sbjct: 283 EIMQDEWFK 291
>KIN4_YEAST (Q01919) Serine/threonine-protein kinase KIN4 (EC 2.7.11.1)| Length = 800 Score = 116 bits (291), Expect = 5e-26 Identities = 55/137 (40%), Positives = 88/137 (64%), Gaps = 8/137 (5%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPE-IINKKGYDGEKADIWS 193 NLL+D+H NL ++DFG + E + + L+ T+CG+P Y APE +++ K Y+ KAD+WS Sbjct: 180 NLLLDKHENLVITDFGF--VNEFFEDNELMKTSCGSPCYAAPELVVSTKAYEARKADVWS 237 Query: 194 CGVILFVLLAGYLPFQD-------SNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPN 352 CGVIL+ +LAGYLP+ D ++ +Y+ I++ +++P++ + R LL R+L PN Sbjct: 238 CGVILYAMLAGYLPWDDDHENPTGDDIARLYKYITQTPLKFPEYITPIPRDLLRRILVPN 297 Query: 353 PNTRITMDKLIEHPWFK 403 P RI + + H W K Sbjct: 298 PRRRINLQTIKRHVWLK 314
>SNF1_CANAL (P52497) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 620 Score = 115 bits (289), Expect = 9e-26 Identities = 62/149 (41%), Positives = 93/149 (62%), Gaps = 1/149 (0%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYV-APEIINKKGYDGEKADIWS 193 NLL+D+ N+K++DFGLS + L T+CG+P Y+ APE+I+ K Y G + D+WS Sbjct: 180 NLLLDDQLNVKIADFGLSNI---MTDGNFLKTSCGSPNYMPAPEVISGKLYAGPEVDVWS 236 Query: 194 CGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITM 373 GVIL+V+L G LPF D + +++KIS G P + S+ A+ LL R+L NP RIT+ Sbjct: 237 AGVILYVMLCGRLPFDDEFIPALFKKISNGVYTLPNYLSAGAKHLLTRMLVVNPLNRITI 296 Query: 374 DKLIEHPWFKKGYKPAVMLGTPRASKDLN 460 +++E WFK+ ++ P SK+ N Sbjct: 297 HEIMEDDWFKQDMPDYLL--PPDLSKNKN 323
>KIN1_YEAST (P13185) Protein kinase KIN1 (EC 2.7.11.1)| Length = 1064 Score = 114 bits (285), Expect = 3e-25 Identities = 51/132 (38%), Positives = 82/132 (62%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 N+++ + +K+ DFGLS + + +KQ LHT CG+ + APE++ Y G + D+WS Sbjct: 274 NIMISDSSEIKIIDFGLSNIYDSRKQ---LHTFCGSLYFAAPELLKANPYTGPEVDVWSF 330 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 GV+LFVL+ G +PF D N ++ KI +G V YPQ S + LL ++L +P R T+ Sbjct: 331 GVVLFVLVCGKVPFDDENSSVLHEKIKQGKVEYPQHLSIEVISLLSKMLVVDPKRRATLK 390 Query: 377 KLIEHPWFKKGY 412 +++EH W +G+ Sbjct: 391 QVVEHHWMVRGF 402
>AAPK2_CAEEL (Q95ZQ4) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMP-activated kinase 2) Length = 626 Score = 114 bits (284), Expect = 3e-25 Identities = 58/131 (44%), Positives = 80/131 (61%), Gaps = 1/131 (0%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDG-LLHTTCGTPAYVAPEIINKKGYDGEKADIWS 193 NLL+DE N+K++DFGLS + DG L T+CG+P Y APE+I+ K Y G + D+WS Sbjct: 215 NLLLDEQNNVKIADFGLSNIMT----DGDFLRTSCGSPNYAAPEVISGKLYAGPEVDVWS 270 Query: 194 CGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITM 373 CGVIL+ LL G LPF D ++ ++RKI G P + LL +L +P R T+ Sbjct: 271 CGVILYALLCGTLPFDDEHVPSLFRKIKSGVFPTPDFLERPIVNLLHHMLCVDPMKRATI 330 Query: 374 DKLIEHPWFKK 406 +I H WF+K Sbjct: 331 KDVIAHEWFQK 341
>AAPK2_PONPY (Q5RD00) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 113 bits (282), Expect = 6e-25 Identities = 56/131 (42%), Positives = 81/131 (61%), Gaps = 1/131 (0%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDG-LLHTTCGTPAYVAPEIINKKGYDGEKADIWS 193 N+L+D H N K++DFGLS + DG L T+CG+P Y APE+I+ + Y G + DIWS Sbjct: 144 NVLLDAHMNAKIADFGLSNIMS----DGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWS 199 Query: 194 CGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITM 373 CGVIL+ LL G LPF D ++ +++KI G P++ + LL +L +P R T+ Sbjct: 200 CGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVDPLKRATI 259 Query: 374 DKLIEHPWFKK 406 + EH WFK+ Sbjct: 260 KDIREHEWFKQ 270
>AAPK2_HUMAN (P54646) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 113 bits (282), Expect = 6e-25 Identities = 56/131 (42%), Positives = 81/131 (61%), Gaps = 1/131 (0%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDG-LLHTTCGTPAYVAPEIINKKGYDGEKADIWS 193 N+L+D H N K++DFGLS + DG L T+CG+P Y APE+I+ + Y G + DIWS Sbjct: 144 NVLLDAHMNAKIADFGLSNMMS----DGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWS 199 Query: 194 CGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITM 373 CGVIL+ LL G LPF D ++ +++KI G P++ + LL +L +P R T+ Sbjct: 200 CGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVDPLKRATI 259 Query: 374 DKLIEHPWFKK 406 + EH WFK+ Sbjct: 260 KDIREHEWFKQ 270
>MARK3_HUMAN (P27448) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| (Cdc25C-associated protein kinase 1) (cTAK1) (C-TAK1) (Serine/threonine protein kinase p78) (Ser/Thr protein kinase PAR-1) (Protein kinase STK10) Length = 776 Score = 113 bits (282), Expect = 6e-25 Identities = 70/215 (32%), Positives = 103/215 (47%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D N+K++DFG S G L T CG+P Y APE+ K YDG + D+WS Sbjct: 206 NLLLDADMNIKIADFGFSNEFTV---GGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSL 262 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 GVIL+ L++G LPF NL E+ ++ +G R P + S+D LL R L NP R T++ Sbjct: 263 GVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLE 322 Query: 377 KLIEHPWFKKGYKPAVMLGTPRASKDLNDVQAAFSTDHKDGEGSRAEQPNSPLKPASLNA 556 ++++ W G++ + D++D + D G G E+ L + Sbjct: 323 QIMKDRWINAGHEEDELKPFVEPELDISDQK---RIDIMVGMGYSQEEIQESLSKMKYDE 379 Query: 557 FDIISLSKGFDLSGLFEKDQEQKSNSRFMTQKPAS 661 L G S L D SN +P+S Sbjct: 380 ITATYLLLGRKSSELDASDSSSSSNLSLAKVRPSS 414
>SNF1_SCHPO (O74536) SNF1-like protein kinase ssp2 (EC 2.7.11.1)| Length = 576 Score = 112 bits (280), Expect = 1e-24 Identities = 54/155 (34%), Positives = 92/155 (59%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D++ N+K++DFGLS + L T+CG+P Y APE+IN K Y G + D+WSC Sbjct: 161 NLLLDDNLNVKIADFGLSNI---MTDGNFLKTSCGSPNYAAPEVINGKLYAGPEVDVWSC 217 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 G++L+V+L G LPF D + +++K++ P + S A+ L+ R++ +P RIT+ Sbjct: 218 GIVLYVMLVGRLPFDDEFIPNLFKKVNSCVYVMPDFLSPGAQSLIRRMIVADPMQRITIQ 277 Query: 377 KLIEHPWFKKGYKPAVMLGTPRASKDLNDVQAAFS 481 ++ PWF + P + + +VQ +++ Sbjct: 278 EIRRDPWFN--------VNLPDYLRPMEEVQGSYA 304
>MARK4_MOUSE (Q8CIP4) MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1)| Length = 752 Score = 111 bits (278), Expect = 2e-24 Identities = 56/151 (37%), Positives = 84/151 (55%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D N+K++DFG S + L T CG+P Y APE+ K YDG + DIWS Sbjct: 186 NLLLDAEANIKIADFGFSNEFTLGSK---LDTFCGSPPYAAPELFQGKKYDGPEVDIWSL 242 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 GVIL+ L++G LPF NL E+ ++ +G R P + S+D +L R L NP R T++ Sbjct: 243 GVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVLNPAKRCTLE 302 Query: 377 KLIEHPWFKKGYKPAVMLGTPRASKDLNDVQ 469 ++++ W GY+ + +D D + Sbjct: 303 QIMKDKWINIGYEGEELKPYTEPEEDFGDTK 333
>MARK4_HUMAN (Q96L34) MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase-like 1) Length = 752 Score = 111 bits (278), Expect = 2e-24 Identities = 56/151 (37%), Positives = 84/151 (55%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D N+K++DFG S + L T CG+P Y APE+ K YDG + DIWS Sbjct: 186 NLLLDAEANIKIADFGFSNEFTLGSK---LDTFCGSPPYAAPELFQGKKYDGPEVDIWSL 242 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 GVIL+ L++G LPF NL E+ ++ +G R P + S+D +L R L NP R T++ Sbjct: 243 GVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVLNPAKRCTLE 302 Query: 377 KLIEHPWFKKGYKPAVMLGTPRASKDLNDVQ 469 ++++ W GY+ + +D D + Sbjct: 303 QIMKDKWINIGYEGEELKPYTEPEEDFGDTK 333
>AAPK1_RAT (P54645) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 548 Score = 111 bits (277), Expect = 2e-24 Identities = 60/153 (39%), Positives = 87/153 (56%), Gaps = 1/153 (0%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDG-LLHTTCGTPAYVAPEIINKKGYDGEKADIWS 193 N+L+D H N K++DFGLS + DG L T+CG+P Y APE+I+ + Y G + DIWS Sbjct: 144 NVLLDAHMNAKIADFGLSNMMS----DGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWS 199 Query: 194 CGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITM 373 GVIL+ LL G LPF D ++ +++KI G PQ+ + LL +L +P R T+ Sbjct: 200 SGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRATI 259 Query: 374 DKLIEHPWFKKGYKPAVMLGTPRASKDLNDVQA 472 + EH WFK+ + P S + D +A Sbjct: 260 KDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEA 292
>AAPK1_PONPY (Q5RDH5) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 550 Score = 111 bits (277), Expect = 2e-24 Identities = 60/153 (39%), Positives = 87/153 (56%), Gaps = 1/153 (0%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDG-LLHTTCGTPAYVAPEIINKKGYDGEKADIWS 193 N+L+D H N K++DFGLS + DG L T+CG+P Y APE+I+ + Y G + DIWS Sbjct: 146 NVLLDAHMNAKIADFGLSNMMS----DGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWS 201 Query: 194 CGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITM 373 GVIL+ LL G LPF D ++ +++KI G PQ+ + LL +L +P R T+ Sbjct: 202 SGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRATI 261 Query: 374 DKLIEHPWFKKGYKPAVMLGTPRASKDLNDVQA 472 + EH WFK+ + P S + D +A Sbjct: 262 KDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEA 294
>AAPK1_HUMAN (Q13131) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 550 Score = 111 bits (277), Expect = 2e-24 Identities = 60/153 (39%), Positives = 87/153 (56%), Gaps = 1/153 (0%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDG-LLHTTCGTPAYVAPEIINKKGYDGEKADIWS 193 N+L+D H N K++DFGLS + DG L T+CG+P Y APE+I+ + Y G + DIWS Sbjct: 146 NVLLDAHMNAKIADFGLSNMMS----DGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWS 201 Query: 194 CGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITM 373 GVIL+ LL G LPF D ++ +++KI G PQ+ + LL +L +P R T+ Sbjct: 202 SGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRATI 261 Query: 374 DKLIEHPWFKKGYKPAVMLGTPRASKDLNDVQA 472 + EH WFK+ + P S + D +A Sbjct: 262 KDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEA 294
>MARK3_RAT (Q8VHF0) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| Length = 797 Score = 110 bits (276), Expect = 3e-24 Identities = 68/215 (31%), Positives = 103/215 (47%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D N+K++DFG S + L T CG+P Y APE+ K YDG + D+WS Sbjct: 183 NLLLDADMNIKITDFGFSNEFTVGSK---LDTFCGSPPYAAPELFQGKKYDGPEVDVWSL 239 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 GVIL+ L++G LPF NL E+ ++ +G R P + S+D LL R L NP R T++ Sbjct: 240 GVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPVKRGTLE 299 Query: 377 KLIEHPWFKKGYKPAVMLGTPRASKDLNDVQAAFSTDHKDGEGSRAEQPNSPLKPASLNA 556 ++++ W G++ + D++D + D G G E+ L + Sbjct: 300 QIMKDRWINAGHEEEELKPFVEPELDISDQK---RIDIMVGMGYSQEEIQESLSKMKYDE 356 Query: 557 FDIISLSKGFDLSGLFEKDQEQKSNSRFMTQKPAS 661 L G + L D SN +P+S Sbjct: 357 ITATYLLLGRKSAELDASDSSSSSNLSLAKVRPSS 391
>AAPK2_PIG (Q28948) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 110 bits (274), Expect = 5e-24 Identities = 55/131 (41%), Positives = 80/131 (61%), Gaps = 1/131 (0%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDG-LLHTTCGTPAYVAPEIINKKGYDGEKADIWS 193 N+L+D N K++DFGLS + DG L T+CG+P Y APE+I+ + Y G + DIWS Sbjct: 144 NVLLDAQMNAKIADFGLSNMMS----DGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWS 199 Query: 194 CGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITM 373 CGVIL+ LL G LPF D ++ +++KI G P++ + LL +L +P R T+ Sbjct: 200 CGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVDPLKRATI 259 Query: 374 DKLIEHPWFKK 406 + EH WFK+ Sbjct: 260 KDIREHEWFKQ 270
>AAPK1_CAEEL (P45894) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMP-activated kinase 1) Length = 589 Score = 110 bits (274), Expect = 5e-24 Identities = 52/129 (40%), Positives = 75/129 (58%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D + N+K++DFGLS LL T CG+P Y APE+I+ K Y G + D+WSC Sbjct: 152 NLLLDANKNIKIADFGLS---NYMTDGDLLSTACGSPNYAAPELISNKLYVGPEVDLWSC 208 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 GVIL+ +L G LPF D N+ ++ KI G P A L+ +L +P R + Sbjct: 209 GVILYAMLCGTLPFDDQNVPTLFAKIKSGRYTVPYSMEKQAADLISTMLQVDPVKRADVK 268 Query: 377 KLIEHPWFK 403 +++ H WF+ Sbjct: 269 RIVNHSWFR 277
>AAPK2_RAT (Q09137) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 109 bits (273), Expect = 7e-24 Identities = 55/131 (41%), Positives = 80/131 (61%), Gaps = 1/131 (0%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDG-LLHTTCGTPAYVAPEIINKKGYDGEKADIWS 193 N+L+D N K++DFGLS + DG L T+CG+P Y APE+I+ + Y G + DIWS Sbjct: 144 NVLLDAQMNAKIADFGLSNMMS----DGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWS 199 Query: 194 CGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITM 373 CGVIL+ LL G LPF D ++ +++KI G P++ + LL +L +P R T+ Sbjct: 200 CGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSIATLLMHMLQVDPLKRATI 259 Query: 374 DKLIEHPWFKK 406 + EH WFK+ Sbjct: 260 KDIREHEWFKQ 270
>KCC4_YEAST (P25389) Probable serine/threonine-protein kinase KCC4 (EC| 2.7.11.1) Length = 1037 Score = 109 bits (272), Expect = 9e-24 Identities = 57/134 (42%), Positives = 84/134 (62%), Gaps = 4/134 (2%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D N+K++DFG++AL Q LL T+CG+P Y APEI++ Y+G +D+WSC Sbjct: 157 NLLLDSFYNIKIADFGMAAL---QTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSC 213 Query: 197 GVILFVLLAGYLPF--QDSNLMEMYRKISKGDVRYPQ--WFSSDARKLLCRLLDPNPNTR 364 GVILF LL G LPF ++ N+ ++ K+ KG P S DA+ L+ ++L +P R Sbjct: 214 GVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQR 273 Query: 365 ITMDKLIEHPWFKK 406 I + ++ HP KK Sbjct: 274 IKIRDILSHPLLKK 287
>AAPK1_MOUSE (Q5EG47) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 548 Score = 109 bits (272), Expect = 9e-24 Identities = 59/153 (38%), Positives = 86/153 (56%), Gaps = 1/153 (0%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDG-LLHTTCGTPAYVAPEIINKKGYDGEKADIWS 193 N+L+D H N K++DFGLS + DG L T+CG+P Y APE+I+ + Y G + DIWS Sbjct: 144 NVLLDAHMNAKIADFGLSNMMS----DGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWS 199 Query: 194 CGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITM 373 GVIL+ LL G LPF D ++ +++KI G PQ+ + LL +L +P R + Sbjct: 200 SGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRAAI 259 Query: 374 DKLIEHPWFKKGYKPAVMLGTPRASKDLNDVQA 472 + EH WFK+ + P S + D +A Sbjct: 260 KDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEA 292
>MARK1_RAT (O08678) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) Length = 793 Score = 109 bits (272), Expect = 9e-24 Identities = 56/151 (37%), Positives = 86/151 (56%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D N+K++DFG S + L T CG+P Y APE+ K YDG + D+WS Sbjct: 187 NLLLDADMNIKIADFGFSNEFTVGNK---LDTFCGSPPYAAPELFQGKKYDGPEVDVWSL 243 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 GVIL+ L++G LPF NL E+ ++ +G R P + S+D LL +LL NP R +++ Sbjct: 244 GVILYTLVSGSLPFDGQNLKELRERVLRGKYRVPFYMSTDCENLLKKLLVLNPIKRGSLE 303 Query: 377 KLIEHPWFKKGYKPAVMLGTPRASKDLNDVQ 469 ++++ W G++ + DLND + Sbjct: 304 QIMKDRWMNVGHEEEELKPYSEPELDLNDAK 334
>MARK3_MOUSE (Q03141) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| (MPK-10) (ELKL motif kinase 2) Length = 753 Score = 109 bits (272), Expect = 9e-24 Identities = 68/215 (31%), Positives = 102/215 (47%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D N+K++DFG S + L T CG+P Y APE+ K YDG + D+WS Sbjct: 183 NLLLDADMNIKIADFGFSNEFTVGSK---LDTFCGSPPYAAPELFQGKKYDGPEVDVWSL 239 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 GVIL+ L++G LPF NL E+ ++ +G R P + S+D LL R L NP R T++ Sbjct: 240 GVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPVKRGTLE 299 Query: 377 KLIEHPWFKKGYKPAVMLGTPRASKDLNDVQAAFSTDHKDGEGSRAEQPNSPLKPASLNA 556 ++++ W G++ + D++D + D G G E+ L + Sbjct: 300 QIMKDRWINAGHEEDELKPFVEPELDISDQK---RIDIMVGMGYSQEEIQESLSKMKYDE 356 Query: 557 FDIISLSKGFDLSGLFEKDQEQKSNSRFMTQKPAS 661 L G + L D SN +P S Sbjct: 357 ITATYLLLGRKSAELDASDSSSSSNLSLAKVRPNS 391
>MARK1_MOUSE (Q8VHJ5) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) (ELKL motif serine/threonine-protein kinase 3) Length = 795 Score = 109 bits (272), Expect = 9e-24 Identities = 56/151 (37%), Positives = 86/151 (56%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D N+K++DFG S + L T CG+P Y APE+ K YDG + D+WS Sbjct: 187 NLLLDADMNIKIADFGFSNEFTVGNK---LDTFCGSPPYAAPELFQGKKYDGPEVDVWSL 243 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 GVIL+ L++G LPF NL E+ ++ +G R P + S+D LL +LL NP R +++ Sbjct: 244 GVILYTLVSGSLPFDGQNLKELRERVLRGKYRVPFYMSTDCENLLKKLLVLNPIKRGSLE 303 Query: 377 KLIEHPWFKKGYKPAVMLGTPRASKDLNDVQ 469 ++++ W G++ + DLND + Sbjct: 304 QIMKDRWMNVGHEEEELKPYSEPELDLNDAK 334
>RKIN1_SECCE (Q02723) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 502 Score = 109 bits (272), Expect = 9e-24 Identities = 56/130 (43%), Positives = 82/130 (63%), Gaps = 1/130 (0%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDG-LLHTTCGTPAYVAPEIINKKGYDGEKADIWS 193 NLL+D N+K++DFGLS + DG L T+CG+ Y APE+I+ K Y G + D+WS Sbjct: 145 NLLLDSKYNVKLADFGLSNVMH----DGHFLKTSCGSLNYAAPEVISGKLYAGPEIDVWS 200 Query: 194 CGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITM 373 CGVIL+ LL G +PF D N+ +++KI G P + S R L+ R+L +P RIT+ Sbjct: 201 CGVILYALLCGAVPFDDDNIPNLFKKIKGGTYILPIYLSDLVRDLISRMLIVDPMKRITI 260 Query: 374 DKLIEHPWFK 403 ++ +H WF+ Sbjct: 261 GEIRKHSWFQ 270
>YP150_YEAST (Q12152) Putative serine/threonine-protein kinase YPL150W (EC| 2.7.11.1) Length = 901 Score = 108 bits (271), Expect = 1e-23 Identities = 55/130 (42%), Positives = 83/130 (63%), Gaps = 1/130 (0%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 N+L+D++GN K++DFG + +EC + L T CGT Y+APE+I ++ YDG K DIWS Sbjct: 162 NILLDKNGNAKLTDFGFT--RECMTKT-TLETVCGTTVYMAPELIERRTYDGFKIDIWSL 218 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRY-PQWFSSDARKLLCRLLDPNPNTRITM 373 GVIL+ L+ GYLPF D + + KI + +Y + DAR L+ RLL NP R ++ Sbjct: 219 GVILYTLITGYLPFDDDDEAKTKWKIVNEEPKYDAKVIPDDARDLISRLLAKNPGERPSL 278 Query: 374 DKLIEHPWFK 403 +++ HP+ + Sbjct: 279 SQVLRHPFLQ 288
>YP141_YEAST (Q03002) Putative serine/threonine-protein kinase YPL141C (EC| 2.7.11.1) Length = 865 Score = 108 bits (271), Expect = 1e-23 Identities = 60/162 (37%), Positives = 96/162 (59%), Gaps = 8/162 (4%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPE-IINKKGYDGEKADIWS 193 NLL+D++ NL ++DFG + E ++ L+ T+CG+P Y APE +I+ + Y+ KADIWS Sbjct: 180 NLLLDKNENLVITDFGF--VNEFCSRNELMKTSCGSPCYAAPELVISAEPYEARKADIWS 237 Query: 194 CGVILFVLLAGYLPFQD-------SNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPN 352 CGVIL+ +LAGYLP+ D S++ +Y I+ +++P + R LL R+L + Sbjct: 238 CGVILYAILAGYLPWDDDPNNPEGSDIGRLYNYINSTPLKFPDYILPIPRDLLRRMLVSD 297 Query: 353 PNTRITMDKLIEHPWFKKGYKPAVMLGTPRASKDLNDVQAAF 478 P RI + ++ +H W K + + TP LN+ Q+ F Sbjct: 298 PKKRINLKQIKKHEWLKP--HSSFLSITPDEWDKLNNTQSVF 337
>GIN4_YEAST (Q12263) Serine/threonine-protein kinase GIN4 (EC 2.7.11.1)| Length = 1142 Score = 108 bits (270), Expect = 1e-23 Identities = 71/210 (33%), Positives = 115/210 (54%), Gaps = 4/210 (1%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D N+K++DFG++AL + + LL T+CG+P Y APEI++ Y G +D+WSC Sbjct: 161 NLLLDHKYNIKIADFGMAAL---ETEGKLLETSCGSPHYAAPEIVSGIPYQGFASDVWSC 217 Query: 197 GVILFVLLAGYLPF--QDSNLMEMYRKISKGDVRYP--QWFSSDARKLLCRLLDPNPNTR 364 GVILF LL G LPF +D N+ + K+ KG+ P S +A+ L+ ++L +P R Sbjct: 218 GVILFALLTGRLPFDEEDGNIRTLLLKVQKGEFEMPSDDEISREAQDLIRKILTVDPERR 277 Query: 365 ITMDKLIEHPWFKKGYKPAVMLGTPRASKDLNDVQAAFSTDHKDGEGSRAEQPNSPLKPA 544 I +++HP +K P++ R SK + + +D + + NS + Sbjct: 278 IKTRDILKHPLLQK--YPSI-----RDSKSIRGL------PREDTYLTPLSESNSSIDAT 324 Query: 545 SLNAFDIISLSKGFDLSGLFEKDQEQKSNS 634 L +++ L G D G+ EK +E +N+ Sbjct: 325 ILQ--NLVILWHGRDPEGIKEKLREPGANA 352
>NUAK1_MOUSE (Q641K5) NUAK family, SNF1-like kinase 1 (EC 2.7.11.1)| Length = 658 Score = 108 bits (269), Expect = 2e-23 Identities = 55/136 (40%), Positives = 85/136 (62%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 N+L+D++ N+K++DFGLS L + +D L T CG+P Y +PEI+N + Y G + D W+ Sbjct: 184 NILLDDNCNIKIADFGLSNLYQ---KDKFLQTFCGSPLYASPEIVNGRPYRGPEVDSWAL 240 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 GV+L+ L+ G +PF + + R+IS G+ R P SDAR L+ +L NP+ R T++ Sbjct: 241 GVLLYTLIYGTMPFDGFDHKNLIRQISSGEYREPTQ-PSDARGLIRWMLMVNPDRRATIE 299 Query: 377 KLIEHPWFKKGYKPAV 424 + H W GYK +V Sbjct: 300 DIANHWWVNWGYKSSV 315
>NUAK1_HUMAN (O60285) NUAK family, SNF1-like kinase 1 (EC 2.7.11.1)| (AMPK-related protein kinase 5) Length = 661 Score = 107 bits (268), Expect = 2e-23 Identities = 55/136 (40%), Positives = 85/136 (62%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 N+L+D++ N+K++DFGLS L + +D L T CG+P Y +PEI+N + Y G + D W+ Sbjct: 183 NILLDDNCNIKIADFGLSNLYQ---KDKFLQTFCGSPLYASPEIVNGRPYRGPEVDSWAL 239 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 GV+L+ L+ G +PF + + R+IS G+ R P SDAR L+ +L NP+ R T++ Sbjct: 240 GVLLYTLVYGTMPFDGFDHKNLIRQISSGEYREPTQ-PSDARGLIRWMLMVNPDRRATIE 298 Query: 377 KLIEHPWFKKGYKPAV 424 + H W GYK +V Sbjct: 299 DIANHWWVNWGYKSSV 314
>MARK1_HUMAN (Q9P0L2) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) Length = 795 Score = 107 bits (268), Expect = 2e-23 Identities = 55/151 (36%), Positives = 85/151 (56%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D N+K++DFG S + L T CG+P Y APE+ K YDG + D+WS Sbjct: 187 NLLLDGDMNIKIADFGFSNEFTVGNK---LDTFCGSPPYAAPELFQGKKYDGPEVDVWSL 243 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 GVIL+ L++G LPF NL E+ ++ +G R P + S+D LL +LL NP R +++ Sbjct: 244 GVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRGSLE 303 Query: 377 KLIEHPWFKKGYKPAVMLGTPRASKDLNDVQ 469 ++++ W G++ + D ND + Sbjct: 304 QIMKDRWMNVGHEEEELKPYTEPDPDFNDTK 334
>KAPA_YEAST (P06244) cAMP-dependent protein kinase type 1 (EC 2.7.11.11) (PKA| 1) (CDC25-suppressing protein kinase) (PK-25) Length = 397 Score = 107 bits (267), Expect = 3e-23 Identities = 50/135 (37%), Positives = 87/135 (64%), Gaps = 5/135 (3%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 N+L+D++G++K++DFG + + + +T CGTP Y+APE+++ K Y+ + D WS Sbjct: 215 NILLDKNGHIKITDFGFA-----KYVPDVTYTLCGTPDYIAPEVVSTKPYN-KSIDWWSF 268 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRI--- 367 G++++ +LAGY PF DSN M+ Y KI ++R+P +F+ D + LL RL+ + + R+ Sbjct: 269 GILIYEMLAGYTPFYDSNTMKTYEKILNAELRFPPFFNEDVKDLLSRLITRDLSQRLGNL 328 Query: 368 --TMDKLIEHPWFKK 406 + + HPWFK+ Sbjct: 329 QNGTEDVKNHPWFKE 343
>MARK2_RAT (O08679) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1) Length = 722 Score = 106 bits (264), Expect = 7e-23 Identities = 52/133 (39%), Positives = 80/133 (60%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D N+K++DFG S + L T CG+P Y APE+ K YDG + D+WS Sbjct: 180 NLLLDADMNIKIADFGFSNEFTFGNK---LDTFCGSPPYAAPELFQGKKYDGPEVDVWSL 236 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 GVIL+ L++G LPF NL E+ ++ +G R P + S+D LL + L NP+ R T++ Sbjct: 237 GVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLE 296 Query: 377 KLIEHPWFKKGYK 415 ++++ W G++ Sbjct: 297 QIMKDRWMNVGHE 309
>KK31_SCHPO (Q9HFF4) Probable serine/threonine-protein kinase C110.01 (EC| 2.7.11.1) Length = 1023 Score = 106 bits (264), Expect = 7e-23 Identities = 58/149 (38%), Positives = 88/149 (59%), Gaps = 20/149 (13%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSA-------LKE----CQKQDGLLHTTCGTPAYVAPEIINKKG 163 N+L+D + N+ ++DFG + L E +K D L T+CG+P Y APE++N K Sbjct: 628 NILLDTNRNIVIADFGFATTFGHFNTLSEHSLPTEKPD-LFSTSCGSPCYAAPELVNCKS 686 Query: 164 --YDGEKADIWSCGVILFVLLAGYLPFQD-------SNLMEMYRKISKGDVRYPQWFSSD 316 Y G +ADIWSCGVIL+ +LAGYLPF D N+ +YR I + +P++F S Sbjct: 687 GMYAGTQADIWSCGVILYAMLAGYLPFDDDPHNPNGENVPRLYRYICSTPLIFPEFFKSK 746 Query: 317 ARKLLCRLLDPNPNTRITMDKLIEHPWFK 403 AR +L ++L P+P R+ M ++ H + + Sbjct: 747 ARDILKKILVPDPAKRVRMSAIMNHAYLR 775
>MARK2_HUMAN (Q7KZI7) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog) Length = 788 Score = 106 bits (264), Expect = 7e-23 Identities = 52/133 (39%), Positives = 80/133 (60%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D N+K++DFG S + L T CG+P Y APE+ K YDG + D+WS Sbjct: 180 NLLLDADMNIKIADFGFSNEFTFGNK---LDTFCGSPPYAAPELFQGKKYDGPEVDVWSL 236 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 GVIL+ L++G LPF NL E+ ++ +G R P + S+D LL + L NP+ R T++ Sbjct: 237 GVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLE 296 Query: 377 KLIEHPWFKKGYK 415 ++++ W G++ Sbjct: 297 QIMKDRWMNVGHE 309
>KCC1G_HUMAN (Q96NX5) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 476 Score = 105 bits (263), Expect = 9e-23 Identities = 51/130 (39%), Positives = 79/130 (60%), Gaps = 4/130 (3%) Frame = +2 Query: 20 LLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSCG 199 L +E+ + ++DFGLS ++ Q+G++ T CGTP YVAPE++ +K Y + D WS G Sbjct: 152 LTPEENSKIMITDFGLSKME----QNGIMSTACGTPGYVAPEVLAQKPYS-KAVDCWSIG 206 Query: 200 VILFVLLAGYLPFQDSNLMEMYRKISKG--DVRYPQW--FSSDARKLLCRLLDPNPNTRI 367 VI ++LL GY PF + +++ KI +G + P W S A+ +C LL+ +PN R Sbjct: 207 VITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAKDFICHLLEKDPNERY 266 Query: 368 TMDKLIEHPW 397 T +K + HPW Sbjct: 267 TCEKALSHPW 276
>KCC1G_RAT (Q7TNJ7) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 476 Score = 105 bits (262), Expect = 1e-22 Identities = 51/130 (39%), Positives = 79/130 (60%), Gaps = 4/130 (3%) Frame = +2 Query: 20 LLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSCG 199 L +E+ + ++DFGLS ++ Q+G++ T CGTP YVAPE++ +K Y + D WS G Sbjct: 152 LTPEENSKIMITDFGLSKME----QNGVMSTACGTPGYVAPEVLAQKPYS-KAVDCWSIG 206 Query: 200 VILFVLLAGYLPFQDSNLMEMYRKISKG--DVRYPQW--FSSDARKLLCRLLDPNPNTRI 367 VI ++LL GY PF + +++ KI +G + P W S A+ +C LL+ +PN R Sbjct: 207 VITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAKDFICHLLEKDPNERY 266 Query: 368 TMDKLIEHPW 397 T +K + HPW Sbjct: 267 TCEKALRHPW 276
>KCC1G_MOUSE (Q91VB2) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 477 Score = 105 bits (262), Expect = 1e-22 Identities = 51/130 (39%), Positives = 79/130 (60%), Gaps = 4/130 (3%) Frame = +2 Query: 20 LLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSCG 199 L +E+ + ++DFGLS ++ Q+G++ T CGTP YVAPE++ +K Y + D WS G Sbjct: 152 LTPEENSKIMITDFGLSKME----QNGVMSTACGTPGYVAPEVLAQKPYS-KAVDCWSIG 206 Query: 200 VILFVLLAGYLPFQDSNLMEMYRKISKG--DVRYPQW--FSSDARKLLCRLLDPNPNTRI 367 VI ++LL GY PF + +++ KI +G + P W S A+ +C LL+ +PN R Sbjct: 207 VITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAKDFICHLLEKDPNERY 266 Query: 368 TMDKLIEHPW 397 T +K + HPW Sbjct: 267 TCEKALRHPW 276
>PLK3_HUMAN (Q9H4B4) Serine/threonine-protein kinase PLK3 (EC 2.7.11.21)| (Polo-like kinase 3) (PLK-3) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) (Proliferation-related kinase) Length = 646 Score = 105 bits (261), Expect = 2e-22 Identities = 55/134 (41%), Positives = 82/134 (61%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 N + E+ LKV DFGL+A E +Q T CGTP YVAPE++ ++G+ G +AD+WS Sbjct: 190 NFFITENMELKVGDFGLAARLEPPEQRK--KTICGTPNYVAPEVLLRQGH-GPEADVWSL 246 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 G +++ LL G PF+ ++L E YR I + P S AR+LL +L +P R ++D Sbjct: 247 GCVMYTLLCGSPPFETADLKETYRCIKQVHYTLPASLSLPARQLLAAILRASPRDRPSID 306 Query: 377 KLIEHPWFKKGYKP 418 +++ H +F KGY P Sbjct: 307 QILRHDFFTKGYTP 320
>CHK1_DROME (O61661) Serine/threonine-protein kinase grp (EC 2.7.11.1) (Protein| grapes) (Chk1 homolog) Length = 512 Score = 105 bits (261), Expect = 2e-22 Identities = 57/133 (42%), Positives = 84/133 (63%), Gaps = 6/133 (4%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+DEH N+K+SDFG++ + C+ ++ LL CGT YVAPE++ +K Y + AD+WSC Sbjct: 148 NLLLDEHDNVKISDFGMATMFRCKGKERLLDKRCGTLPYVAPEVL-QKAYHAQPADLWSC 206 Query: 197 GVILFVLLAGYLPFQ--DSNLMEM--YRKISKGDVRYPQWFSSD--ARKLLCRLLDPNPN 358 GVIL +LAG LP+ +N E +R ++ P W D A LL +LL +P Sbjct: 207 GVILVTMLAGELPWDQPSTNCTEFTNWRDNDHWQLQTP-WSKLDTLAISLLRKLLATSPG 265 Query: 359 TRITMDKLIEHPW 397 TR+T++K ++H W Sbjct: 266 TRLTLEKTLDHKW 278
>SAPK2_ORYSA (Q84TC6) Serine/threonine-protein kinase SAPK2 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 2) Length = 339 Score = 104 bits (260), Expect = 2e-22 Identities = 66/177 (37%), Positives = 94/177 (53%), Gaps = 21/177 (11%) Frame = +2 Query: 44 LKVSDFGLSALKECQKQDGLLHT----TCGTPAYVAPEIINKKGYDGEKADIWSCGVILF 211 LK+ DFG S + LLH+ T GTPAY+APE++ +K YDG+ AD+WSCGV L+ Sbjct: 139 LKICDFGYS-------KSSLLHSQPKSTVGTPAYIAPEVLARKEYDGKVADVWSCGVTLY 191 Query: 212 VLLAGYLPFQDSNLMEMYRK----ISKGDVRYPQW--FSSDARKLLCRLLDPNPNTRITM 373 V+L G PF+D + +RK I P + S + R LL R+ NP RIT+ Sbjct: 192 VMLVGAYPFEDPDEPRNFRKTITRILSVQYMVPDYVRVSMECRHLLSRIFVANPEQRITI 251 Query: 374 DKLIEHPWFKKG--------YKPAVM---LGTPRASKDLNDVQAAFSTDHKDGEGSR 511 ++ HPWF K Y+ +V + TP S+ L ++ A K G+GS+ Sbjct: 252 PEIKNHPWFLKNLPIEMTDEYQMSVQMNDINTP--SQGLEEIMAIIQEARKPGDGSK 306
>SN1L2_CHICK (Q9IA88) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Qin-induced kinase) Length = 798 Score = 104 bits (259), Expect = 3e-22 Identities = 51/129 (39%), Positives = 76/129 (58%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D + N+K++DFG K L T CG+P Y APE+ K Y+G DIWS Sbjct: 153 NLLLDANMNIKLADFGFGNF---YKSGEPLSTWCGSPPYAAPEVFEGKEYEGPHLDIWSL 209 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 GV+L+VL+ G LPF NL + +++ +G R P + S D L+ R+L +P RIT+ Sbjct: 210 GVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPYFMSEDCETLIRRMLVVDPTKRITIS 269 Query: 377 KLIEHPWFK 403 ++ +H W + Sbjct: 270 QIKQHKWMQ 278
>CDR1_SCHPO (P07334) Mitosis inducer protein kinase cdr1 (EC 2.7.11.1) (Protein| kinase nim1) Length = 593 Score = 103 bits (258), Expect = 4e-22 Identities = 52/118 (44%), Positives = 74/118 (62%) Frame = +2 Query: 44 LKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSCGVILFVLLA 223 +K++DFG++ + + D L CG+ Y+APEI++ K Y G AD+WSCGVIL+ LL+ Sbjct: 143 IKIADFGMATV---EPNDSCLENYCGSLHYLAPEIVSHKPYRGAPADVWSCGVILYSLLS 199 Query: 224 GYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMDKLIEHPW 397 LPF N +Y KI G P SS A+ LL R+LD NP+TRIT+ ++ HP+ Sbjct: 200 NKLPFGGQNTDVIYNKIRHGAYDLPSSISSAAQDLLHRMLDVNPSTRITIPEVFSHPF 257
>KS6A2_MOUSE (Q9WUT3) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (Protein-tyrosine kinase Mpk-9) (MAP kinase-activated protein kinase 1c) (M Length = 733 Score = 103 bits (257), Expect = 5e-22 Identities = 75/222 (33%), Positives = 112/222 (50%), Gaps = 20/222 (9%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 N+L+DE G++K++DFGLS KE D ++ CGT Y+APE++N++G+ + AD WS Sbjct: 189 NILLDEEGHIKITDFGLS--KEATDHDKRAYSFCGTIEYMAPEVVNRRGHT-QSADWWSF 245 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRI--- 367 GV++F +L G LPFQ + E I K + PQ+ S++A+ LL L NP R+ Sbjct: 246 GVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSAEAQSLLRALFKRNPCNRLGAG 305 Query: 368 --TMDKLIEHPWF-------------KKGYKPAVMLGTPRASKDLNDVQAAFSTDHKDGE 502 ++++ HP+F K +KPAV G P T H D E Sbjct: 306 VDGVEEIKRHPFFVTIDWNKLYRKEIKPPFKPAV--GRPE------------DTFHFDPE 351 Query: 503 GSRAEQPNSPLKPASLNAFDIISLSKGFDL--SGLFEKDQEQ 622 + +SP P S NA L +GF S L ++ +Q Sbjct: 352 FTARTPTDSPGVPPSANAH---HLFRGFSFVASSLVQEPSQQ 390 Score = 84.7 bits (208), Expect = 2e-16 Identities = 49/136 (36%), Positives = 81/136 (59%), Gaps = 10/136 (7%) Frame = +2 Query: 20 LLVDEHGN---LKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIW 190 L +DE GN +++ DFG + K+ + ++GLL T C T +VAPE++ ++GYD D+W Sbjct: 539 LYMDESGNPESIRICDFGFA--KQLRAENGLLMTPCYTANFVAPEVLKRQGYDA-ACDVW 595 Query: 191 SCGVILFVLLAGYLPF---QDSNLMEMYRKISKGDVRYP--QWFS-SDARK-LLCRLLDP 349 S G++L+ +LAG+ PF D E+ +I G W S SDA K ++ ++L Sbjct: 596 SLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDVVSKMLHV 655 Query: 350 NPNTRITMDKLIEHPW 397 +P R+T ++++HPW Sbjct: 656 DPQQRLTAVQVLKHPW 671
>SAPK1_ORYSA (Q75LR7) Serine/threonine-protein kinase SAPK1 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 1) Length = 342 Score = 103 bits (256), Expect = 6e-22 Identities = 64/173 (36%), Positives = 91/173 (52%), Gaps = 17/173 (9%) Frame = +2 Query: 44 LKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSCGVILFVLLA 223 LK+ DFG S Q +T GTPAY+APE++++K YDG+ AD+WSCGV L+V+L Sbjct: 139 LKICDFGYSKSSVLHSQP---KSTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLYVMLV 195 Query: 224 GYLPFQDSNLMEMYRK----ISKGDVRYPQW--FSSDARKLLCRLLDPNPNTRITMDKLI 385 G PF+D + +RK I P + S+D R LL R+ NP RIT+ ++ Sbjct: 196 GAYPFEDPDDPRNFRKTITRILSVQYSIPDYVRVSADCRHLLSRIFVGNPEQRITIPEIK 255 Query: 386 EHPWFKKG--------YKPAVML---GTPRASKDLNDVQAAFSTDHKDGEGSR 511 HPWF K Y+ ++ L TP S+ L +V A K G+ + Sbjct: 256 NHPWFLKNLPIEMTDEYQRSMQLADMNTP--SQSLEEVMAIIQEARKPGDAMK 306
>MARK2_MOUSE (Q05512) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1) Length = 776 Score = 103 bits (256), Expect = 6e-22 Identities = 51/133 (38%), Positives = 79/133 (59%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D N+K++DFG S + L T CG+P Y APE+ K DG + D+WS Sbjct: 180 NLLLDADMNIKIADFGFSNEFTFGNK---LDTFCGSPPYAAPELFQGKKIDGPEVDVWSL 236 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 GVIL+ L++G LPF NL E+ ++ +G R P + S+D LL + L NP+ R T++ Sbjct: 237 GVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLE 296 Query: 377 KLIEHPWFKKGYK 415 ++++ W G++ Sbjct: 297 QIMKDRWMNVGHE 309
>PLO1_SCHPO (P50528) Serine/threonine-protein kinase plo1 (EC 2.7.11.21)| Length = 683 Score = 103 bits (256), Expect = 6e-22 Identities = 53/141 (37%), Positives = 88/141 (62%), Gaps = 4/141 (2%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEII--NKKGYDGEKADIW 190 N+++DE N+K+ DFGL+AL ++ + T CGTP Y+APEI+ +K+G+ E D+W Sbjct: 168 NIMLDESNNVKIGDFGLAALLMDDEERKM--TICGTPNYIAPEILFNSKEGHSFE-VDLW 224 Query: 191 SCGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQ--WFSSDARKLLCRLLDPNPNTR 364 S GV+++ LL G PFQD + +YRKI +P S++A+ L+ LL +P+ R Sbjct: 225 SAGVVMYALLIGKPPFQDKEVKTIYRKIKANSYSFPSNVDISAEAKDLISSLLTHDPSIR 284 Query: 365 ITMDKLIEHPWFKKGYKPAVM 427 ++D +++H +F GY + + Sbjct: 285 PSIDDIVDHEFFHTGYMASTL 305
>STK6L_XENLA (Q91819) Serine/threonine-protein kinase Eg2-like (EC 2.7.11.1)| (p46XlEg22) Length = 408 Score = 103 bits (256), Expect = 6e-22 Identities = 52/130 (40%), Positives = 78/130 (60%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+ +G LK++DFG S ++ T CGT Y+ PE+I + +D EK D+WS Sbjct: 268 NLLLGSNGELKIADFGWSVHAPSSRRT----TLCGTLDYLPPEMIEGRMHD-EKVDLWSL 322 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 GV+ + L G PF+ E YR+ISK + +YP + S +A+ L+ +LL NPN R+ + Sbjct: 323 GVLCYEFLVGKPPFETDTHQETYRRISKVEFQYPPYVSEEAKDLVSKLLKHNPNHRLPLK 382 Query: 377 KLIEHPWFKK 406 ++EHPW K Sbjct: 383 GVLEHPWIVK 392
>SAPK6_ORYSA (Q6ZI44) Serine/threonine-protein kinase SAPK6 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 6) Length = 365 Score = 102 bits (255), Expect = 8e-22 Identities = 55/131 (41%), Positives = 80/131 (61%), Gaps = 10/131 (7%) Frame = +2 Query: 44 LKVSDFGLSALKECQKQDGLLHT----TCGTPAYVAPEIINKKGYDGEKADIWSCGVILF 211 LK+ DFG S + LLH+ T GTPAY+APE+++++ YDG+ AD+WSCGV L+ Sbjct: 139 LKICDFGYS-------KSSLLHSKPKSTVGTPAYIAPEVLSRREYDGKMADVWSCGVTLY 191 Query: 212 VLLAGYLPFQDSNLMEMYRK----ISKGDVRYPQW--FSSDARKLLCRLLDPNPNTRITM 373 V+L G PF+D + + +RK I + P++ S D R+LL R+ NP RIT+ Sbjct: 192 VMLVGAYPFEDPDDPKNFRKTIGRIVSIQYKIPEYVHISQDCRQLLSRIFVANPAKRITI 251 Query: 374 DKLIEHPWFKK 406 ++ HPWF K Sbjct: 252 REIRNHPWFMK 262
>KS6A2_HUMAN (Q15349) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (MAP kinase-activated protein kinase 1c) (MAPKAPK1C) Length = 733 Score = 102 bits (255), Expect = 8e-22 Identities = 75/222 (33%), Positives = 111/222 (50%), Gaps = 20/222 (9%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 N+L+DE G++K++DFGLS KE D ++ CGT Y+APE++N++G+ + AD WS Sbjct: 189 NILLDEEGHIKITDFGLS--KEAIDHDKRAYSFCGTIEYMAPEVVNRRGHT-QSADWWSF 245 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRI--- 367 GV++F +L G LPFQ + E I K + PQ+ S +A+ LL L NP R+ Sbjct: 246 GVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQSLLRALFKRNPCNRLGAG 305 Query: 368 --TMDKLIEHPWF-------------KKGYKPAVMLGTPRASKDLNDVQAAFSTDHKDGE 502 ++++ HP+F K +KPAV G P T H D E Sbjct: 306 IDGVEEIKRHPFFVTIDWNTLYRKEIKPPFKPAV--GRPE------------DTFHFDPE 351 Query: 503 GSRAEQPNSPLKPASLNAFDIISLSKGFDL--SGLFEKDQEQ 622 + +SP P S NA L +GF S L ++ +Q Sbjct: 352 FTARTPTDSPGVPPSANAH---HLFRGFSFVASSLIQEPSQQ 390 Score = 80.9 bits (198), Expect = 3e-15 Identities = 49/133 (36%), Positives = 79/133 (59%), Gaps = 10/133 (7%) Frame = +2 Query: 29 DEHGN---LKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSCG 199 DE G+ ++V DFG + K+ + +GLL T C T +VAPE++ ++GYD DIWS G Sbjct: 542 DESGSPESIRVCDFGFA--KQLRAGNGLLMTPCYTANFVAPEVLKRQGYDA-ACDIWSLG 598 Query: 200 VILFVLLAGYLPF---QDSNLMEMYRKISKGDVRYP--QWFS-SDARK-LLCRLLDPNPN 358 ++L+ +LAG+ PF D E+ +I G W S SDA K ++ ++L +P+ Sbjct: 599 ILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDVVSKMLHVDPH 658 Query: 359 TRITMDKLIEHPW 397 R+T ++++HPW Sbjct: 659 QRLTAMQVLKHPW 671
>PLK3_MOUSE (Q60806) Serine/threonine-protein kinase PLK3 (EC 2.7.11.21)| (Polo-like kinase 3) (PLK-3) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) Length = 631 Score = 102 bits (254), Expect = 1e-21 Identities = 53/134 (39%), Positives = 82/134 (61%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 N + ++ LKV DFGL+A E +Q T CGTP YVAPE++ ++G+ G +AD+WS Sbjct: 191 NFFITDNMELKVGDFGLAARLEPPEQRK--KTICGTPNYVAPEVLLRQGH-GPEADVWSL 247 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 G +++ LL G PF+ ++L E YR I + P S AR+LL +L +P R +++ Sbjct: 248 GCVMYTLLCGSPPFETADLKETYRCIKQVHYTLPASLSLPARQLLAAILRASPRDRPSIE 307 Query: 377 KLIEHPWFKKGYKP 418 +++ H +F KGY P Sbjct: 308 QILRHDFFTKGYTP 321
>SN1L2_HUMAN (Q9H0K1) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Qin-induced kinase) Length = 926 Score = 102 bits (254), Expect = 1e-21 Identities = 50/127 (39%), Positives = 77/127 (60%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D + N+K++DFG K LL T CG+P Y APE+ + Y+G + DIWS Sbjct: 147 NLLLDNNMNIKIADFGFGNFF---KSGELLATWCGSPPYAAPEVFEGQQYEGPQLDIWSM 203 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 GV+L+VL+ G LPF L + +++ +G R P + S D L+ R+L +P+ R+T+ Sbjct: 204 GVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPSKRLTIA 263 Query: 377 KLIEHPW 397 ++ EH W Sbjct: 264 QIKEHKW 270
>PLK3_RAT (Q9R011) Serine/threonine-protein kinase PLK3 (EC 2.7.11.21)| (Polo-like kinase 3) (PLK-3) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) (Fragment) Length = 615 Score = 102 bits (254), Expect = 1e-21 Identities = 53/134 (39%), Positives = 82/134 (61%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 N + ++ LKV DFGL+A E +Q T CGTP YVAPE++ ++G+ G +AD+WS Sbjct: 159 NFFITDNMELKVGDFGLAARLEPPEQRK--KTICGTPNYVAPEVLLRQGH-GPEADVWSL 215 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 G +++ LL G PF+ ++L E YR I + P S AR+LL +L +P R +++ Sbjct: 216 GCVMYTLLCGSPPFETADLKETYRCIKQVHYTLPASLSLPARQLLAAILRASPRDRPSIE 275 Query: 377 KLIEHPWFKKGYKP 418 +++ H +F KGY P Sbjct: 276 QILRHDFFTKGYTP 289
>SAPK7_ORYSA (Q7XQP4) Serine/threonine-protein kinase SAPK7 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 7) Length = 359 Score = 102 bits (254), Expect = 1e-21 Identities = 55/131 (41%), Positives = 80/131 (61%), Gaps = 10/131 (7%) Frame = +2 Query: 44 LKVSDFGLSALKECQKQDGLLHT----TCGTPAYVAPEIINKKGYDGEKADIWSCGVILF 211 LK+ DFG S + LLH+ T GTPAY+APE+++++ YDG+ AD+WSCGV L+ Sbjct: 139 LKICDFGYS-------KSSLLHSKPKSTVGTPAYIAPEVLSRREYDGKTADVWSCGVTLY 191 Query: 212 VLLAGYLPFQDSNLMEMYRK----ISKGDVRYPQW--FSSDARKLLCRLLDPNPNTRITM 373 V+L G PF+D + + +RK I + P++ S D R+LL R+ NP RIT+ Sbjct: 192 VMLVGAYPFEDPDDPKNFRKTIGRIMSIQYKIPEYVHVSQDCRQLLSRIFVANPAKRITI 251 Query: 374 DKLIEHPWFKK 406 ++ HPWF K Sbjct: 252 REIRNHPWFLK 262
>STK6_XENLA (Q91820) Serine/threonine-protein kinase Eg2 (EC 2.7.11.1) (pEg2)| (p46Eg265) Length = 407 Score = 101 bits (252), Expect = 2e-21 Identities = 52/130 (40%), Positives = 77/130 (59%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+ +G LK++DFG S ++ T CGT Y+ PE+I + +D E D+WS Sbjct: 268 NLLLGSNGELKIADFGWSVHAPSSRRT----TLCGTLDYLPPEMIEGRMHD-ETVDLWSL 322 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 GV+ + L G PF+ E YR+ISK + +YP + S +AR L+ +LL NPN R+ + Sbjct: 323 GVLCYEFLVGKPPFETDTHQETYRRISKVEFQYPPYVSEEARDLVSKLLKHNPNHRLPLK 382 Query: 377 KLIEHPWFKK 406 ++EHPW K Sbjct: 383 GVLEHPWIIK 392
>SN1L1_HUMAN (P57059) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) Length = 783 Score = 100 bits (250), Expect = 3e-21 Identities = 50/129 (38%), Positives = 77/129 (59%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D + ++K++DFG K L T CG+P Y APE+ K Y+G + DIWS Sbjct: 154 NLLLDGNMDIKLADFGFGNF---YKSGEPLSTWCGSPPYAAPEVFEGKEYEGPQLDIWSL 210 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 GV+L+VL+ G LPF NL + +++ +G R P + S D L+ R+L +P RIT+ Sbjct: 211 GVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCESLIRRMLVVDPARRITIA 270 Query: 377 KLIEHPWFK 403 ++ +H W + Sbjct: 271 QIRQHRWMR 279
>SAPK9_ORYSA (Q75V57) Serine/threonine-protein kinase SAPK9 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 9) Length = 361 Score = 100 bits (250), Expect = 3e-21 Identities = 55/134 (41%), Positives = 75/134 (55%), Gaps = 6/134 (4%) Frame = +2 Query: 44 LKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSCGVILFVLLA 223 LK+ DFG S Q +T GTPAY+APE++ KK YDG+ AD+WSCGV L+V+L Sbjct: 157 LKICDFGYSKSSVLHSQP---KSTVGTPAYIAPEVLLKKEYDGKIADVWSCGVTLYVMLV 213 Query: 224 GYLPFQD----SNLMEMYRKISKGDVRYPQW--FSSDARKLLCRLLDPNPNTRITMDKLI 385 G PF+D N + +KI P + S + R L+ R+ NP +RITM ++ Sbjct: 214 GAYPFEDPEDPKNFRKTIQKILGVQYSIPDYVHISPECRDLITRIFVGNPASRITMPEIK 273 Query: 386 EHPWFKKGYKPAVM 427 HPWF K +M Sbjct: 274 NHPWFMKNIPADLM 287
>SN1L2_MOUSE (Q8CFH6) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Salt-inducible kinase 2) Length = 931 Score = 100 bits (249), Expect = 4e-21 Identities = 49/127 (38%), Positives = 77/127 (60%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D + N+K++DFG K LL T CG+P Y APE+ + Y+G + DIWS Sbjct: 147 NLLLDNNMNIKIADFGFGNFF---KTGELLATWCGSPPYAAPEVFEGQQYEGPQLDIWSM 203 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 GV+L+VL+ G LPF L + +++ +G R P + S D L+ R+L +P+ R+++ Sbjct: 204 GVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPSKRLSIA 263 Query: 377 KLIEHPW 397 ++ EH W Sbjct: 264 QIKEHKW 270
>TSSK1_HUMAN (Q9BXA7) Testis-specific serine/threonine-protein kinase 1 (EC| 2.7.11.1) (TSSK-1) (Testis-specific kinase 1) (TSK-1) (Serine/threonine-protein kinase 22A) Length = 367 Score = 100 bits (249), Expect = 4e-21 Identities = 59/183 (32%), Positives = 98/183 (53%), Gaps = 6/183 (3%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDG----LLHTTCGTPAYVAPEIINKKGYDGEKAD 184 NLL+D+ N+K+SDF S K C + D L T CG+PAY APE++ Y + D Sbjct: 141 NLLLDKDFNIKLSDFSFS--KRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIPYQPKVYD 198 Query: 185 IWSCGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYP--QWFSSDARKLLCRLLDPNPN 358 IWS GVIL++++ G +P+ DSN+ +M R + V +P + + + + L+ +L P+ N Sbjct: 199 IWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKHLTGECKDLIYHMLQPDVN 258 Query: 359 TRITMDKLIEHPWFKKGYKPAVMLGTPRASKDLNDVQAAFSTDHKDGEGSRAEQPNSPLK 538 R+ +D+++ H W + + G+P + +K+GE SR +P + Sbjct: 259 RRLHIDEILSHCWMQPKAR-----GSPSVA------------INKEGESSRGTEPLWTPE 301 Query: 539 PAS 547 P S Sbjct: 302 PGS 304
>CHK1_XENLA (Q6DE87) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (xChk1| protein) Length = 474 Score = 100 bits (248), Expect = 5e-21 Identities = 65/208 (31%), Positives = 107/208 (51%), Gaps = 15/208 (7%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+DE LK+SDFGL+ + ++ LL+ CGT YVAPE+I + + + D+WSC Sbjct: 135 NLLLDERDQLKISDFGLATVFRHNGKERLLNKMCGTLPYVAPELIKSRAFHADPVDVWSC 194 Query: 197 GVILFVLLAGYLPF-QDSNLMEMYRKISKGDVRYPQW--FSSDARKLLCRLLDPNPNTRI 367 G++L +LAG LP+ Q + + + Y + + W S+ LLC++L NP +RI Sbjct: 195 GIVLTAMLAGELPWDQPNEVCQEYCDWKEKNHYLTPWKKISATPLALLCKMLTENPQSRI 254 Query: 368 TMDKLIEHPWF----KKGYKPAVML--GTPRASKDLNDVQAAFSTDH------KDGEGSR 511 T+ + + WF KKG K + ++ G+ +S +++ H K S Sbjct: 255 TIPDIKKDRWFTEIIKKGLKRSRVISGGSSDSSVLCKQIRSDIDISHFSHSEEKTALSST 314 Query: 512 AEQPNSPLKPASLNAFDIISLSKGFDLS 595 +P + L N+ I +L +G +S Sbjct: 315 QPEPRTALATWDSNSSYIDNLVQGKGIS 342
>SN1L1_RAT (Q9R1U5) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (Salt-inducible protein kinase) (Protein kinase KID2) Length = 776 Score = 99.8 bits (247), Expect = 7e-21 Identities = 50/129 (38%), Positives = 77/129 (59%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D + ++K++DFG K L T CG+P Y APE+ K Y+G + DIWS Sbjct: 154 NLLLDGNMDIKLADFGFGNF---YKPGEPLSTWCGSPPYAAPEVFEGKEYEGPQLDIWSL 210 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 GV+L+VL+ G LPF NL + +++ +G R P + S D L+ R+L +P RIT+ Sbjct: 211 GVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCETLIRRMLVVDPAKRITIA 270 Query: 377 KLIEHPWFK 403 ++ +H W + Sbjct: 271 QIRQHRWMQ 279
>PLK2_RAT (Q9R012) Serine/threonine-protein kinase PLK2 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-2) (Serine/threonine-protein kinase SNK) (Serum-inducible kinase) Length = 682 Score = 99.8 bits (247), Expect = 7e-21 Identities = 50/134 (37%), Positives = 80/134 (59%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 N ++E LKV DFGL+A E + T CGTP Y++PE++NK+G+ G ++DIW+ Sbjct: 207 NFFINEAMELKVGDFGLAARLE--PLEHRRRTICGTPNYLSPEVLNKQGH-GCESDIWAL 263 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 G +++ +L G PF+ +NL E YR I + P + A+ L+ +L NP R ++D Sbjct: 264 GCVMYTMLLGRPPFETTNLKETYRCIREARYTMPSSLLAPAKHLIASMLSKNPEDRPSLD 323 Query: 377 KLIEHPWFKKGYKP 418 +I H +F +G+ P Sbjct: 324 DIIRHDFFLQGFTP 337
>PLK2_MOUSE (P53351) Serine/threonine-protein kinase PLK2 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-2) (Serine/threonine-protein kinase SNK) (Serum-inducible kinase) Length = 682 Score = 99.8 bits (247), Expect = 7e-21 Identities = 50/134 (37%), Positives = 80/134 (59%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 N ++E LKV DFGL+A E + T CGTP Y++PE++NK+G+ G ++DIW+ Sbjct: 207 NFFINEAMELKVGDFGLAARLE--PLEHRRRTICGTPNYLSPEVLNKQGH-GCESDIWAL 263 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 G +++ +L G PF+ +NL E YR I + P + A+ L+ +L NP R ++D Sbjct: 264 GCVMYTMLLGRPPFETTNLKETYRCIREARYTMPSSLLAPAKHLIASMLSKNPEDRPSLD 323 Query: 377 KLIEHPWFKKGYKP 418 +I H +F +G+ P Sbjct: 324 DIIRHDFFLQGFTP 337
>SAPKA_ORYSA (Q75H77) Serine/threonine-protein kinase SAPK10 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 10) Length = 362 Score = 99.8 bits (247), Expect = 7e-21 Identities = 57/146 (39%), Positives = 84/146 (57%), Gaps = 6/146 (4%) Frame = +2 Query: 44 LKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSCGVILFVLLA 223 LK+ DFG S Q +T GTPAY+APE++ KK YDG+ AD+WSCGV L+V+L Sbjct: 158 LKICDFGYSKSSVLHSQP---KSTVGTPAYIAPEVLLKKEYDGKIADVWSCGVTLYVMLV 214 Query: 224 GYLPFQDSNLMEMYRKISKG--DVRY--PQW--FSSDARKLLCRLLDPNPNTRITMDKLI 385 G PF+D + + +RK + V+Y P + S + R L+ R+ NP TRI++ ++ Sbjct: 215 GAYPFEDPDEPKNFRKTIQRILGVQYSIPDYVHISPECRDLIARIFVANPATRISIPEIR 274 Query: 386 EHPWFKKGYKPAVMLGTPRASKDLND 463 HPWF K PA ++ + S + Sbjct: 275 NHPWFLKNL-PADLMDDSKMSSQYEE 299
>PLK2_HUMAN (Q9NYY3) Serine/threonine-protein kinase PLK2 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-2) (Serine/threonine-protein kinase SNK) (Serum-inducible kinase) Length = 685 Score = 99.8 bits (247), Expect = 7e-21 Identities = 50/134 (37%), Positives = 80/134 (59%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 N ++E LKV DFGL+A E + T CGTP Y++PE++NK+G+ G ++DIW+ Sbjct: 210 NFFINEAMELKVGDFGLAARLE--PLEHRRRTICGTPNYLSPEVLNKQGH-GCESDIWAL 266 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 G +++ +L G PF+ +NL E YR I + P + A+ L+ +L NP R ++D Sbjct: 267 GCVMYTMLLGRPPFETTNLKETYRCIREARYTMPSSLLAPAKHLIASMLSKNPEDRPSLD 326 Query: 377 KLIEHPWFKKGYKP 418 +I H +F +G+ P Sbjct: 327 DIIRHDFFLQGFTP 340
>KKCC2_MOUSE (Q8C078) Calcium/calmodulin-dependent protein kinase kinase 2 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta) Length = 588 Score = 99.8 bits (247), Expect = 7e-21 Identities = 50/131 (38%), Positives = 80/131 (61%), Gaps = 4/131 (3%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIIN--KKGYDGEKADIW 190 NLLV E G++K++DFG+S E + D LL T GTPA++APE ++ +K + G+ D+W Sbjct: 317 NLLVGEDGHIKIADFGVS--NEFKGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVW 374 Query: 191 SCGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQW--FSSDARKLLCRLLDPNPNTR 364 + GV L+ + G PF D +M ++ KI + +P + D + L+ R+LD NP +R Sbjct: 375 AMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESR 434 Query: 365 ITMDKLIEHPW 397 I + ++ HPW Sbjct: 435 IVVPEIKLHPW 445
>KKCC2_HUMAN (Q96RR4) Calcium/calmodulin-dependent protein kinase kinase 2 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta) Length = 588 Score = 99.8 bits (247), Expect = 7e-21 Identities = 50/131 (38%), Positives = 80/131 (61%), Gaps = 4/131 (3%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIIN--KKGYDGEKADIW 190 NLLV E G++K++DFG+S E + D LL T GTPA++APE ++ +K + G+ D+W Sbjct: 317 NLLVGEDGHIKIADFGVS--NEFKGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVW 374 Query: 191 SCGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQW--FSSDARKLLCRLLDPNPNTR 364 + GV L+ + G PF D +M ++ KI + +P + D + L+ R+LD NP +R Sbjct: 375 AMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESR 434 Query: 365 ITMDKLIEHPW 397 I + ++ HPW Sbjct: 435 IVVPEIKLHPW 445
>STK6_MOUSE (P97477) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Aurora-family kinase 1) (Aurora/IPL1-related kinase 1) (Ipl1- and aurora-related kinase 1) (Aurora-A) (Serine/threonine-protein kinase Ayk1) Length = 395 Score = 99.8 bits (247), Expect = 7e-21 Identities = 50/129 (38%), Positives = 77/129 (59%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+ +G LK++DFG S ++ T CGT Y+ PE+I + +D EK D+WS Sbjct: 252 NLLLGSNGELKIADFGWSVHAPSSRRT----TMCGTLDYLPPEMIEGRMHD-EKVDLWSL 306 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 GV+ + L G PF+ E YR+IS+ + +P + + AR L+ RLL N + R+T+ Sbjct: 307 GVLCYEFLVGMPPFEAHTYQETYRRISRVEFTFPDFVTEGARDLISRLLKHNASQRLTLA 366 Query: 377 KLIEHPWFK 403 +++EHPW K Sbjct: 367 EVLEHPWIK 375
>KAPB_YEAST (P06245) cAMP-dependent protein kinase type 2 (EC 2.7.11.11) (PKA| 2) Length = 380 Score = 99.8 bits (247), Expect = 7e-21 Identities = 54/135 (40%), Positives = 80/135 (59%), Gaps = 5/135 (3%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 N+L+D +G++K++DFG + KE Q + T CGTP Y+APE+I K Y+ + D WS Sbjct: 198 NILLDRNGHIKITDFGFA--KEVQT---VTWTLCGTPDYIAPEVITTKPYN-KSVDWWSL 251 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRI--- 367 GV+++ +LAGY PF D+ M+ Y KI +G V YP +F D LL +L+ + RI Sbjct: 252 GVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYPPYFHPDVVDLLSKLITADLTRRIGNL 311 Query: 368 --TMDKLIEHPWFKK 406 + HPWF + Sbjct: 312 QSGSRDIKAHPWFSE 326
>KKCC2_RAT (O88831) Calcium/calmodulin-dependent protein kinase kinase 2 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta) Length = 587 Score = 99.8 bits (247), Expect = 7e-21 Identities = 50/131 (38%), Positives = 80/131 (61%), Gaps = 4/131 (3%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIIN--KKGYDGEKADIW 190 NLLV E G++K++DFG+S E + D LL T GTPA++APE ++ +K + G+ D+W Sbjct: 316 NLLVGEDGHIKIADFGVS--NEFKGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVW 373 Query: 191 SCGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQW--FSSDARKLLCRLLDPNPNTR 364 + GV L+ + G PF D +M ++ KI + +P + D + L+ R+LD NP +R Sbjct: 374 AMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESR 433 Query: 365 ITMDKLIEHPW 397 I + ++ HPW Sbjct: 434 IVVPEIKLHPW 444
>KAPC_YEAST (P05986) cAMP-dependent protein kinase type 3 (EC 2.7.11.11) (PKA| 3) Length = 398 Score = 99.4 bits (246), Expect = 9e-21 Identities = 47/135 (34%), Positives = 85/135 (62%), Gaps = 5/135 (3%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 N+L+D++G++K++DFG + + + +T CGTP Y+APE+++ K Y+ + D WS Sbjct: 216 NILLDKNGHIKITDFGFA-----KYVPDVTYTLCGTPDYIAPEVVSTKPYN-KSVDWWSF 269 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRI--- 367 GV+++ +LAGY PF +SN M+ Y I ++++P +F DA+ LL +L+ + + R+ Sbjct: 270 GVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFFHPDAQDLLKKLITRDLSERLGNL 329 Query: 368 --TMDKLIEHPWFKK 406 + + HPWF + Sbjct: 330 QNGSEDVKNHPWFNE 344
>KKCC1_MOUSE (Q8VBY2) Calcium/calmodulin-dependent protein kinase kinase 1 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-kinase kinase alpha) (CaM-KK alpha) (CaMKK alpha) (CaMKK 1) (CaM-kinase IV kinase) Length = 505 Score = 99.4 bits (246), Expect = 9e-21 Identities = 51/134 (38%), Positives = 81/134 (60%), Gaps = 4/134 (2%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKG--YDGEKADIW 190 NLL+ + G++K++DFG+S + + D L +T GTPA++APE I+ G + G+ D+W Sbjct: 280 NLLLGDDGHVKIADFGVS--NQFEGNDAQLSSTAGTPAFMAPEAISDSGQSFSGKALDVW 337 Query: 191 SCGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQ--WFSSDARKLLCRLLDPNPNTR 364 + GV L+ + G PF D ++ ++RKI V +P+ S D + L+ R+LD NP TR Sbjct: 338 ATGVTLYCFVYGKCPFIDDYILTLHRKIKNEAVVFPEEPEVSEDLKDLILRMLDKNPETR 397 Query: 365 ITMDKLIEHPWFKK 406 I + + HPW K Sbjct: 398 IGVSDIKLHPWVTK 411
>KCC1A_RAT (Q63450) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 374 Score = 99.0 bits (245), Expect = 1e-20 Identities = 48/128 (37%), Positives = 76/128 (59%), Gaps = 4/128 (3%) Frame = +2 Query: 26 VDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSCGVI 205 +DE + +SDFGLS +++ +L T CGTP YVAPE++ +K Y + D WS GVI Sbjct: 152 LDEDSKIMISDFGLSKMED---PGSVLSTACGTPGYVAPEVLAQKPYS-KAVDCWSIGVI 207 Query: 206 LFVLLAGYLPFQDSNLMEMYRKISKGDVRY--PQW--FSSDARKLLCRLLDPNPNTRITM 373 ++LL GY PF D N +++ +I K + + P W S A+ + L++ +P R T Sbjct: 208 AYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTC 267 Query: 374 DKLIEHPW 397 ++ ++HPW Sbjct: 268 EQALQHPW 275
>KCC1A_MOUSE (Q91YS8) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 374 Score = 99.0 bits (245), Expect = 1e-20 Identities = 48/128 (37%), Positives = 76/128 (59%), Gaps = 4/128 (3%) Frame = +2 Query: 26 VDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSCGVI 205 +DE + +SDFGLS +++ +L T CGTP YVAPE++ +K Y + D WS GVI Sbjct: 152 LDEDSKIMISDFGLSKMED---PGSVLSTACGTPGYVAPEVLAQKPYS-KAVDCWSIGVI 207 Query: 206 LFVLLAGYLPFQDSNLMEMYRKISKGDVRY--PQW--FSSDARKLLCRLLDPNPNTRITM 373 ++LL GY PF D N +++ +I K + + P W S A+ + L++ +P R T Sbjct: 208 AYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTC 267 Query: 374 DKLIEHPW 397 ++ ++HPW Sbjct: 268 EQALQHPW 275
>SAPK3_ORYSA (Q75V63) Serine/threonine-protein kinase SAPK3 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 3) (Protein kinase REK) Length = 334 Score = 99.0 bits (245), Expect = 1e-20 Identities = 61/154 (39%), Positives = 90/154 (58%), Gaps = 10/154 (6%) Frame = +2 Query: 44 LKVSDFGLSALKECQKQDGLLHT----TCGTPAYVAPEIINKKGYDGEKADIWSCGVILF 211 +K+ DFG S + LLH+ T GTPAY+APE++++K YDG+ AD+WSCGV L+ Sbjct: 140 VKICDFGYS-------KSALLHSKPKSTVGTPAYIAPEVLSRKEYDGKVADVWSCGVTLY 192 Query: 212 VLLAGYLPFQDSNLMEMYRK-ISK-GDVRY--PQW--FSSDARKLLCRLLDPNPNTRITM 373 V+L G PF+D +RK IS+ V+Y P + SSD R+LL ++ +P+ RIT+ Sbjct: 193 VMLVGSYPFEDPGDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFVADPSKRITI 252 Query: 374 DKLIEHPWFKKGYKPAVMLGTPRASKDLNDVQAA 475 ++ +H WF K + + R D D AA Sbjct: 253 PEIKKHTWFLKNLPKEI---SEREKADYKDTDAA 283
>SAPK5_ORYSA (Q7XKA8) Serine/threonine-protein kinase SAPK5 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 5) Length = 370 Score = 99.0 bits (245), Expect = 1e-20 Identities = 53/131 (40%), Positives = 76/131 (58%), Gaps = 10/131 (7%) Frame = +2 Query: 44 LKVSDFGLSALKECQKQDGLLHT----TCGTPAYVAPEIINKKGYDGEKADIWSCGVILF 211 LK+ DFG S + LLH+ T GTPAY+APE+++++ YDG+ AD+WSCGV L+ Sbjct: 139 LKICDFGYS-------KSSLLHSRPKSTVGTPAYIAPEVLSRREYDGKLADVWSCGVTLY 191 Query: 212 VLLAGYLPFQD----SNLMEMYRKISKGDVRYPQW--FSSDARKLLCRLLDPNPNTRITM 373 V+L G PF+D N + +I + P++ S R LL R+ NP RI+M Sbjct: 192 VMLVGAYPFEDPKDPKNFRKTISRIMSVQYKIPEYVHVSQPCRHLLSRIFVANPYKRISM 251 Query: 374 DKLIEHPWFKK 406 ++ HPWF K Sbjct: 252 GEIKSHPWFLK 262
>KCC1A_HUMAN (Q14012) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 370 Score = 99.0 bits (245), Expect = 1e-20 Identities = 48/128 (37%), Positives = 76/128 (59%), Gaps = 4/128 (3%) Frame = +2 Query: 26 VDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSCGVI 205 +DE + +SDFGLS +++ +L T CGTP YVAPE++ +K Y + D WS GVI Sbjct: 152 LDEDSKIMISDFGLSKMED---PGSVLSTACGTPGYVAPEVLAQKPYS-KAVDCWSIGVI 207 Query: 206 LFVLLAGYLPFQDSNLMEMYRKISKGDVRY--PQW--FSSDARKLLCRLLDPNPNTRITM 373 ++LL GY PF D N +++ +I K + + P W S A+ + L++ +P R T Sbjct: 208 AYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTC 267 Query: 374 DKLIEHPW 397 ++ ++HPW Sbjct: 268 EQALQHPW 275
>KAPB_SCHPO (P40376) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) Length = 512 Score = 99.0 bits (245), Expect = 1e-20 Identities = 57/135 (42%), Positives = 78/135 (57%), Gaps = 6/135 (4%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D G+LK+ DFG + T CGTP Y+APEII+ K Y+ + AD WS Sbjct: 329 NLLLDRFGHLKIVDFGFAKRVSTSN----CCTLCGTPDYLAPEIISLKPYN-KAADWWSL 383 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRI--- 367 G+++F +LAGY PF N M++Y I +G V YP +FS + LL LL + R Sbjct: 384 GILIFEMLAGYPPFYSENPMKLYENILEGKVNYPSYFSPASIDLLSHLLQRDITCRYGNL 443 Query: 368 ---TMDKLIEHPWFK 403 +MD +I HPWF+ Sbjct: 444 KDGSMD-IIMHPWFR 457
>PHKG2_RAT (P31325) Phosphorylase b kinase gamma catalytic chain, testis/liver| isoform (EC 2.7.11.19) (PHK-gamma-T) (Phosphorylase kinase gamma subunit 2) Length = 406 Score = 98.6 bits (244), Expect = 2e-20 Identities = 57/147 (38%), Positives = 89/147 (60%), Gaps = 13/147 (8%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDG-LLHTTCGTPAYVAPEIIN------KKGYDGE 175 N+L+D++ +++SDFG S C + G L CGTP Y+APEI+ GY G+ Sbjct: 158 NILLDDNMQIRLSDFGFS----CHLEPGEKLRELCGTPGYLAPEILKCSMDETHPGY-GK 212 Query: 176 KADIWSCGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRY--PQW--FSSDARKLLCRLL 343 + D+W+CGVILF LLAG PF + M R I +G ++ P+W S+ + L+ +LL Sbjct: 213 EVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSPEWDDRSNTVKDLIAKLL 272 Query: 344 DPNPNTRITMDKLIEHPWFK--KGYKP 418 +PN R+T ++ ++HP+F+ KG +P Sbjct: 273 QVDPNARLTAEQALQHPFFERCKGSQP 299
>STK6_RAT (P59241) Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Aurora-A)| (ratAurA) Length = 397 Score = 98.6 bits (244), Expect = 2e-20 Identities = 50/129 (38%), Positives = 76/129 (58%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+ +G LK++DFG S ++ T CGT Y PE+I + +D EK D+WS Sbjct: 254 NLLLGSNGELKIADFGWSVHAPSSRRT----TLCGTLDYQPPEMIEGRMHD-EKVDLWSL 308 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 GV+ + L G PF+ E YR+IS+ + +P + + AR L+ RLL N + R+T+ Sbjct: 309 GVLCYEFLVGMPPFEAHTYQETYRRISRVEFTFPDFVTEGARDLISRLLKHNSSQRLTLA 368 Query: 377 KLIEHPWFK 403 +++EHPW K Sbjct: 369 EVLEHPWIK 377
>SAPK4_ORYSA (Q5N942) Serine/threonine-protein kinase SAPK4 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 4) Length = 360 Score = 98.6 bits (244), Expect = 2e-20 Identities = 50/131 (38%), Positives = 79/131 (60%), Gaps = 10/131 (7%) Frame = +2 Query: 44 LKVSDFGLSALKECQKQDGLLHT----TCGTPAYVAPEIINKKGYDGEKADIWSCGVILF 211 LK+ DFG S + +LH+ GTPAY+APE+++++ YDG+ AD+WSCGV L+ Sbjct: 139 LKICDFGYS-------KSSVLHSRPKSAVGTPAYIAPEVLSRREYDGKLADVWSCGVTLY 191 Query: 212 VLLAGYLPFQD----SNLMEMYRKISKGDVRYPQW--FSSDARKLLCRLLDPNPNTRITM 373 V+L G PF+D N+ + ++I + P + S++ ++L+ R+ NP RITM Sbjct: 192 VMLVGAYPFEDQDDPKNIRKTIQRIMSVQYKIPDYVHISAECKQLIARIFVNNPLRRITM 251 Query: 374 DKLIEHPWFKK 406 ++ HPWF K Sbjct: 252 KEIKSHPWFLK 262
>KS6A6_HUMAN (Q9UK32) Ribosomal protein S6 kinase alpha-6 (EC 2.7.11.1)| (S6K-alpha 6) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4) Length = 745 Score = 98.6 bits (244), Expect = 2e-20 Identities = 72/198 (36%), Positives = 106/198 (53%), Gaps = 8/198 (4%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 N+L+DE G++K++DFGLS KE Q+ ++ CGT Y+APE++N++G+ + AD WS Sbjct: 203 NILLDEIGHIKLTDFGLS--KESVDQEKKAYSFCGTVEYMAPEVVNRRGHS-QSADWWSY 259 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRI--- 367 GV++F +L G LPFQ + E I K + PQ+ S++A+ LL L NP R+ Sbjct: 260 GVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSAEAQSLLRMLFKRNPANRLGSE 319 Query: 368 TMDKLIEHPWF-----KKGYKPAVMLGTPRASKDLNDVQAAFSTDHKDGEGSRAEQPNSP 532 ++++ H +F K YK V AS +D T D E + +SP Sbjct: 320 GVEEIKRHLFFANIDWDKLYKREVQPPFKPASGKPDD------TFCFDPEFTAKTPKDSP 373 Query: 533 LKPASLNAFDIISLSKGF 586 PAS NA L KGF Sbjct: 374 GLPASANAH---QLFKGF 388 Score = 77.0 bits (188), Expect = 5e-14 Identities = 43/126 (34%), Positives = 73/126 (57%), Gaps = 7/126 (5%) Frame = +2 Query: 41 NLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSCGVILFVLL 220 ++++ DFG + K+ + ++GLL T C T +VAPE++ ++GYD DIWS GV+ + +L Sbjct: 560 SIRICDFGFA--KQLRGENGLLLTPCYTANFVAPEVLMQQGYDA-ACDIWSLGVLFYTML 616 Query: 221 AGYLPF---QDSNLMEMYRKISKG--DVRYPQW--FSSDARKLLCRLLDPNPNTRITMDK 379 AGY PF + E+ +I G + W S A+ LL +L +P+ R T ++ Sbjct: 617 AGYTPFANGPNDTPEEILLRIGNGKFSLSGGNWDNISDGAKDLLSHMLHMDPHQRYTAEQ 676 Query: 380 LIEHPW 397 +++H W Sbjct: 677 ILKHSW 682
>PK2_DICDI (P28178) Protein kinase 2 (EC 2.7.11.1)| Length = 479 Score = 98.2 bits (243), Expect = 2e-20 Identities = 59/173 (34%), Positives = 93/173 (53%), Gaps = 16/173 (9%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 N+L+D G++ ++DFGLS K+ + DG T CGTP Y+APE++N G+ G D WS Sbjct: 281 NILLDSEGHICITDFGLS--KKIETTDGTF-TFCGTPEYLAPEVLNGHGH-GCAVDWWSL 336 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITM- 373 G +L+ +L G PF N+ MY+KI G+++ P + S +A+ LL LL + R+ Sbjct: 337 GTLLYEMLTGLPPFYSQNVSTMYQKILNGELKIPTYISPEAKSLLEGLLTREVDKRLGTK 396 Query: 374 --DKLIEHPWFKK-------------GYKPAVMLGTPRASKDLNDVQAAFSTD 487 ++ +HPWFK +KP V GT D++ + F+ + Sbjct: 397 GGGEVKQHPWFKNIDWEKLDRKEVEVHFKPKVKSGT-----DISQIDPVFTQE 444
>KAPC_DICDI (P34099) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) Length = 648 Score = 97.8 bits (242), Expect = 3e-20 Identities = 51/133 (38%), Positives = 77/133 (57%), Gaps = 5/133 (3%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D G++K++DFG + ++ + T CGTP Y+APEII KG+ G+ D W+ Sbjct: 464 NLLIDNQGHIKITDFGFA-----KRVEDRTFTLCGTPEYLAPEIIQSKGH-GKAVDWWAL 517 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 G+++F +LAGY PF D + +Y KI G + +P F DA+ L+ RLL + R+ Sbjct: 518 GILIFEMLAGYPPFYDDDTFAIYNKILAGRITFPLGFDVDAKDLIKRLLTADRTRRLGAL 577 Query: 377 K-----LIEHPWF 400 K + H WF Sbjct: 578 KDGALDVKNHRWF 590
>PLK1_MOUSE (Q07832) Serine/threonine-protein kinase PLK1 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13) Length = 603 Score = 97.8 bits (242), Expect = 3e-20 Identities = 51/135 (37%), Positives = 79/135 (58%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NL ++E +K+ DFGL+ E + + T CGTP Y+APE+++KKG+ E D+WS Sbjct: 181 NLFLNEDLEVKIGDFGLATKVEYEGERK--KTLCGTPNYIAPEVLSKKGHSFE-VDVWSI 237 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 G I++ LL G PF+ S L E Y +I K + P+ + A L+ ++L +P R T+ Sbjct: 238 GCIMYTLLVGKPPFETSCLKETYLRIKKNEYSIPKHINPVAASLIQKMLQTDPTARPTIH 297 Query: 377 KLIEHPWFKKGYKPA 421 +L+ +F GY PA Sbjct: 298 ELLNDEFFTSGYIPA 312
>PLK1_HUMAN (P53350) Serine/threonine-protein kinase PLK1 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13) Length = 603 Score = 97.8 bits (242), Expect = 3e-20 Identities = 51/135 (37%), Positives = 79/135 (58%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NL ++E +K+ DFGL+ E + T CGTP Y+APE+++KKG+ E D+WS Sbjct: 181 NLFLNEDLEVKIGDFGLATKVEYDGERK--KTLCGTPNYIAPEVLSKKGHSFE-VDVWSI 237 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 G I++ LL G PF+ S L E Y +I K + P+ + A L+ ++L +P R T++ Sbjct: 238 GCIMYTLLVGKPPFETSCLKETYLRIKKNEYSIPKHINPVAASLIQKMLQTDPTARPTIN 297 Query: 377 KLIEHPWFKKGYKPA 421 +L+ +F GY PA Sbjct: 298 ELLNDEFFTSGYIPA 312
>CHK1_RAT (Q91ZN7) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 97.8 bits (242), Expect = 3e-20 Identities = 51/133 (38%), Positives = 78/133 (58%), Gaps = 3/133 (2%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+DE NLK+SDFGL+ + ++ LL+ CGT YVAPE++ +K + E D+WSC Sbjct: 135 NLLLDERDNLKISDFGLATVFRHNNRERLLNKMCGTLPYVAPELLKRKEFHAEPVDVWSC 194 Query: 197 GVILFVLLAGYLPF-QDSNLMEMYRKISKGDVRYPQWFSSDAR--KLLCRLLDPNPNTRI 367 G++L +LAG LP+ Q S+ + Y + W D+ LL ++L NP+ RI Sbjct: 195 GIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARI 254 Query: 368 TMDKLIEHPWFKK 406 T+ + + W+ K Sbjct: 255 TIPDIKKDRWYNK 267
>CHK1_HUMAN (O14757) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 97.8 bits (242), Expect = 3e-20 Identities = 51/136 (37%), Positives = 79/136 (58%), Gaps = 3/136 (2%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+DE NLK+SDFGL+ + ++ LL+ CGT YVAPE++ ++ + E D+WSC Sbjct: 135 NLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSC 194 Query: 197 GVILFVLLAGYLPF-QDSNLMEMYRKISKGDVRYPQWFSSDAR--KLLCRLLDPNPNTRI 367 G++L +LAG LP+ Q S+ + Y + W D+ LL ++L NP+ RI Sbjct: 195 GIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARI 254 Query: 368 TMDKLIEHPWFKKGYK 415 T+ + + W+ K K Sbjct: 255 TIPDIKKDRWYNKPLK 270
>KCC1D_MOUSE (Q8BW96) Calcium/calmodulin-dependent protein kinase type 1D (EC| 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) (mCKLiK) Length = 385 Score = 97.4 bits (241), Expect = 3e-20 Identities = 48/127 (37%), Positives = 74/127 (58%), Gaps = 4/127 (3%) Frame = +2 Query: 29 DEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSCGVIL 208 DE + +SDFGLS + + + ++ T CGTP YVAPE++ +K Y + D WS GVI Sbjct: 156 DEESKIMISDFGLSKM---EGKGDVMSTACGTPGYVAPEVLAQKPYS-KAVDCWSIGVIA 211 Query: 209 FVLLAGYLPFQDSNLMEMYRKISKGDVRY--PQW--FSSDARKLLCRLLDPNPNTRITMD 376 ++LL GY PF D N +++ +I K + + P W S A+ + L++ +PN R T + Sbjct: 212 YILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCE 271 Query: 377 KLIEHPW 397 + HPW Sbjct: 272 QAARHPW 278
>KCC1D_HUMAN (Q8IU85) Calcium/calmodulin-dependent protein kinase type 1D (EC| 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) Length = 385 Score = 97.4 bits (241), Expect = 3e-20 Identities = 48/127 (37%), Positives = 74/127 (58%), Gaps = 4/127 (3%) Frame = +2 Query: 29 DEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSCGVIL 208 DE + +SDFGLS + + + ++ T CGTP YVAPE++ +K Y + D WS GVI Sbjct: 156 DEESKIMISDFGLSKM---EGKGDVMSTACGTPGYVAPEVLAQKPYS-KAVDCWSIGVIA 211 Query: 209 FVLLAGYLPFQDSNLMEMYRKISKGDVRY--PQW--FSSDARKLLCRLLDPNPNTRITMD 376 ++LL GY PF D N +++ +I K + + P W S A+ + L++ +PN R T + Sbjct: 212 YILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCE 271 Query: 377 KLIEHPW 397 + HPW Sbjct: 272 QAARHPW 278
>PHKG2_HUMAN (P15735) Phosphorylase b kinase gamma catalytic chain, testis/liver| isoform (EC 2.7.11.19) (PHK-gamma-T) (Phosphorylase kinase gamma subunit 2) (PSK-C3) Length = 406 Score = 97.4 bits (241), Expect = 3e-20 Identities = 55/141 (39%), Positives = 85/141 (60%), Gaps = 11/141 (7%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDG-LLHTTCGTPAYVAPEIIN------KKGYDGE 175 N+L+D++ +++SDFG S C + G L CGTP Y+APEI+ GY G+ Sbjct: 158 NILLDDNMQIRLSDFGFS----CHLEPGEKLRELCGTPGYLAPEILKCSMDETHPGY-GK 212 Query: 176 KADIWSCGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRY--PQW--FSSDARKLLCRLL 343 + D+W+CGVILF LLAG PF + M R I +G ++ P+W SS + L+ RLL Sbjct: 213 EVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSPEWDDRSSTVKDLISRLL 272 Query: 344 DPNPNTRITMDKLIEHPWFKK 406 +P R+T ++ ++HP+F++ Sbjct: 273 QVDPEARLTAEQALQHPFFER 293
>KPSH1_BRARE (Q501V0) Serine/threonine-protein kinase H1 homolog (EC 2.7.11.1)| Length = 422 Score = 97.1 bits (240), Expect = 4e-20 Identities = 59/187 (31%), Positives = 104/187 (55%), Gaps = 6/187 (3%) Frame = +2 Query: 44 LKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSCGVILFVLLA 223 + ++DFGL++ ++ + + L+ TTCGTP Y+APEI+ +K Y D+W+ GVI ++LL+ Sbjct: 233 IMITDFGLASTRK-KGDECLMKTTCGTPEYIAPEILVRKPYTNA-VDMWALGVISYILLS 290 Query: 224 GYLPFQDSNLMEMYRKISKGDVRY--PQW--FSSDARKLLCRLLDPNPNTRITMDKLIEH 391 G +PF+D N M +YR+I KG + W S+ A+ + R+L +PN R++ + ++H Sbjct: 291 GTMPFEDDNRMRLYRQILKGKYSFSGEPWPSVSNLAKDFIDRVLTVDPNERLSAGQALKH 350 Query: 392 PWFKKGYKPAVMLGTPRASKDLNDVQAAFSTDH--KDGEGSRAEQPNSPLKPASLNAFDI 565 PW + M R S N ++ A S H K + +R+ + K L ++ Sbjct: 351 PWIVSMAASSSMKNLHR-SISQNLLKRASSRCHSTKSSQSARSSRSTKSSKARRLREKEL 409 Query: 566 ISLSKGF 586 L++ + Sbjct: 410 RELNRRY 416
>KKCC1_HUMAN (Q8N5S9) Calcium/calmodulin-dependent protein kinase kinase 1 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-kinase kinase alpha) (CaM-KK alpha) (CaMKK alpha) (CaMKK 1) (CaM-kinase IV kinase) Length = 505 Score = 97.1 bits (240), Expect = 4e-20 Identities = 51/139 (36%), Positives = 84/139 (60%), Gaps = 5/139 (3%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKG--YDGEKADIW 190 NLL+ + G++K++DFG+S + + D L +T GTPA++APE I+ G + G+ D+W Sbjct: 280 NLLLGDDGHVKIADFGVS--NQFEGNDAQLSSTAGTPAFMAPEAISDSGQSFSGKALDVW 337 Query: 191 SCGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQ--WFSSDARKLLCRLLDPNPNTR 364 + GV L+ + G PF D ++ ++RKI V +P+ S + + L+ ++LD NP TR Sbjct: 338 ATGVTLYCFVYGKCPFIDDFILALHRKIKNEPVVFPEEPEISEELKDLILKMLDKNPETR 397 Query: 365 ITMDKLIEHPWF-KKGYKP 418 I + + HPW K G +P Sbjct: 398 IGVPDIKLHPWVTKNGEEP 416
>PLK1_RAT (Q62673) Serine/threonine-protein kinase PLK1 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-1) Length = 603 Score = 97.1 bits (240), Expect = 4e-20 Identities = 51/135 (37%), Positives = 79/135 (58%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NL ++E +K+ DFGL+ E + + T CGTP Y+APE+++KKG+ E D+WS Sbjct: 181 NLFLNEDLEVKIGDFGLATKVEYEGERK--KTLCGTPNYIAPEVLSKKGHSFE-VDVWSI 237 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 G I++ LL G PF+ S L E Y +I K + P+ + A L+ ++L +P R T+ Sbjct: 238 GCIMYTLLVGKPPFETSCLKETYLRIKKNEYSIPKHINPVAASLIQKMLQTDPAARPTIH 297 Query: 377 KLIEHPWFKKGYKPA 421 +L+ +F GY PA Sbjct: 298 ELLNDEFFTSGYIPA 312
>PLK1_XENLA (P70032) Serine/threonine-protein kinase PLK1 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-1) (Plx1) Length = 598 Score = 97.1 bits (240), Expect = 4e-20 Identities = 51/135 (37%), Positives = 78/135 (57%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NL +++ +K+ DFGL+ E + T CGTP Y+APE++ KKG+ E DIWS Sbjct: 172 NLFLNDEMEVKIGDFGLATKVEYDGERK--KTLCGTPNYIAPEVLGKKGHSFE-VDIWSI 228 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 G I++ LL G PF+ S L E Y +I K + P+ + A L+ ++L +P +R T+D Sbjct: 229 GCIMYTLLVGKPPFETSCLKETYMRIKKNEYSIPKHINPVAAALIQKMLRSDPTSRPTID 288 Query: 377 KLIEHPWFKKGYKPA 421 L+ +F GY P+ Sbjct: 289 DLLNDEFFTSGYIPS 303
>AAIP_WHEAT (Q02066) Abscisic acid-inducible protein kinase (EC 2.7.11.1)| (Fragment) Length = 332 Score = 96.7 bits (239), Expect = 6e-20 Identities = 57/147 (38%), Positives = 79/147 (53%), Gaps = 6/147 (4%) Frame = +2 Query: 44 LKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSCGVILFVLLA 223 LK+ DFG S Q +T GTPAY+APE+++++ YDG+ AD+WSCGV L+V+L Sbjct: 129 LKICDFGYSKSSVLHSQP---KSTVGTPAYIAPEVLSRREYDGKVADVWSCGVTLYVMLV 185 Query: 224 GYLPFQDSNLMEMYRK----ISKGDVRYPQW--FSSDARKLLCRLLDPNPNTRITMDKLI 385 G PF+D + +RK I P + S D LL R+ NP RIT+ ++ Sbjct: 186 GAYPFEDPDEPRNFRKTITRILSVQYSVPDYVRVSMDCIHLLSRIFVGNPQQRITIPEIK 245 Query: 386 EHPWFKKGYKPAVMLGTPRASKDLNDV 466 HPWF K P M + S L D+ Sbjct: 246 NHPWFLKRL-PVEMTDEYQRSMQLADM 271
>ASK2_ARATH (P43292) Serine/threonine-protein kinase ASK2 (EC 2.7.11.1)| Length = 353 Score = 96.7 bits (239), Expect = 6e-20 Identities = 54/145 (37%), Positives = 84/145 (57%), Gaps = 10/145 (6%) Frame = +2 Query: 44 LKVSDFGLSALKECQKQDGLLHT----TCGTPAYVAPEIINKKGYDGEKADIWSCGVILF 211 LK+ DFG S + +LH+ T GTPAY+APE+++++ YDG+ AD+WSCGV L+ Sbjct: 139 LKICDFGYS-------KSSILHSRPKSTVGTPAYIAPEVLSRREYDGKHADVWSCGVTLY 191 Query: 212 VLLAGYLPFQDSNLMEMYRK----ISKGDVRYPQW--FSSDARKLLCRLLDPNPNTRITM 373 V+L G PF+D N + +RK I + P + S + + LL R+ N RIT+ Sbjct: 192 VMLVGAYPFEDPNDPKNFRKTIQRIMAVQYKIPDYVHISQECKHLLSRIFVTNSAKRITL 251 Query: 374 DKLIEHPWFKKGYKPAVMLGTPRAS 448 ++ HPW+ K P +L + +A+ Sbjct: 252 KEIKNHPWYLKNL-PKELLESAQAA 275
>SN1L1_MOUSE (Q60670) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (HRT-20) (Myocardial SNF1-like kinase) Length = 779 Score = 96.7 bits (239), Expect = 6e-20 Identities = 48/129 (37%), Positives = 76/129 (58%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D + ++K++DFG K L T G+P Y APE+ K Y+G + D+WS Sbjct: 154 NLLLDSNMDIKLADFGFGNF---YKPGEPLSTCVGSPPYAAPEVFEGKEYEGPQLDVWSL 210 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 GV+L+VL+ G LPF NL + +++ +G R P + S D L+ R+L +P RIT+ Sbjct: 211 GVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCETLIRRMLVVDPAKRITIA 270 Query: 377 KLIEHPWFK 403 ++ +H W + Sbjct: 271 QIRQHRWMQ 279
>KKCC1_RAT (P97756) Calcium/calmodulin-dependent protein kinase kinase 1 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-kinase kinase alpha) (CaM-KK alpha) (CaMKK alpha) (alpha CaMKK) (CaMKK 1) (CaM-kinase IV kinase) Length = 505 Score = 96.3 bits (238), Expect = 8e-20 Identities = 49/134 (36%), Positives = 81/134 (60%), Gaps = 4/134 (2%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKG--YDGEKADIW 190 NLL+ + G++K++DFG+S + + D L +T GTPA++APE I+ G + G+ D+W Sbjct: 280 NLLLGDDGHVKIADFGVS--NQFEGNDAQLSSTAGTPAFMAPEAISDTGQSFSGKALDVW 337 Query: 191 SCGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQ--WFSSDARKLLCRLLDPNPNTR 364 + GV L+ + G PF D ++ ++RKI V +P+ S + + L+ ++LD NP TR Sbjct: 338 ATGVTLYCFVYGKCPFIDEYILALHRKIKNEAVVFPEEPEVSEELKDLILKMLDKNPETR 397 Query: 365 ITMDKLIEHPWFKK 406 I + + HPW K Sbjct: 398 IGVSDIKLHPWVTK 411
>AURKC_HUMAN (Q9UQB9) Serine/threonine-protein kinase 13 (EC 2.7.11.1)| (Aurora/Ipl1/Eg2 protein 2) (Aurora/Ipl1-related kinase 3) (Aurora-C) Length = 309 Score = 96.3 bits (238), Expect = 8e-20 Identities = 51/127 (40%), Positives = 75/127 (59%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+ G +K++DFG S ++ T CGT Y+ PE+I + YD EK D+W Sbjct: 171 NLLLGFRGEVKIADFGWSVHTPSLRRK----TMCGTLDYLPPEMIEGRTYD-EKVDLWCI 225 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 GV+ + LL GY PF+ ++ E YR+I K DVR+P AR L+ RLL P R+ + Sbjct: 226 GVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDLISRLLRYQPLERLPLA 285 Query: 377 KLIEHPW 397 ++++HPW Sbjct: 286 QILKHPW 292
>KRAC_DICDI (P54644) RAC-family serine/threonine-protein kinase homolog (EC| 2.7.11.1) Length = 444 Score = 96.3 bits (238), Expect = 8e-20 Identities = 54/136 (39%), Positives = 82/136 (60%), Gaps = 7/136 (5%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTT------CGTPAYVAPEIINKKGYDGEK 178 NLL+ G++ ++DFGL ++GLL T CGTP Y+APE++ GY G++ Sbjct: 248 NLLLTNEGHICMTDFGLC-------KEGLLTPTDKTGTFCGTPEYLAPEVLQGNGY-GKQ 299 Query: 179 ADIWSCGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPN 358 D WS G +L+ +L G PF + ++ EMYRKI + +P + S DAR LL +LL+ +P Sbjct: 300 VDWWSFGSLLYEMLTGLPPFYNQDVQEMYRKIMMEKLSFPHFISPDARSLLEQLLERDPE 359 Query: 359 TRITMDKLIE-HPWFK 403 R+ LI+ HP+F+ Sbjct: 360 KRLADPNLIKRHPFFR 375
>DCAK2_HUMAN (Q8N568) Serine/threonine-protein kinase DCAMKL2 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 2) Length = 766 Score = 96.3 bits (238), Expect = 8e-20 Identities = 55/137 (40%), Positives = 83/137 (60%), Gaps = 10/137 (7%) Frame = +2 Query: 17 NLLVDEHGN----LKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKAD 184 NLLV E+ + LK+ DFGL+ + E G L+T CGTP YVAPEII + GY G K D Sbjct: 520 NLLVCEYPDGTKSLKLGDFGLATVVE-----GPLYTVCGTPTYVAPEIIAETGY-GLKVD 573 Query: 185 IWSCGVILFVLLAGYLPFQDSNLM--EMYRKISKGDVRY--PQW--FSSDARKLLCRLLD 346 IW+ GVI ++LL G+ PF+ N + +++ +I G + + P W + A++L+ ++L Sbjct: 574 IWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQMLQ 633 Query: 347 PNPNTRITMDKLIEHPW 397 N R T +++ HPW Sbjct: 634 VNVEARCTAGQILSHPW 650
>PLK1_XENTR (P62205) Serine/threonine-protein kinase PLK1 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-1) (Plx1) Length = 598 Score = 96.3 bits (238), Expect = 8e-20 Identities = 51/135 (37%), Positives = 77/135 (57%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NL +++ +K+ DFGL+ E + T CGTP Y+APE++ KKG+ E DIWS Sbjct: 172 NLFLNDEMEVKIGDFGLATKVEYDGERK--KTLCGTPNYIAPEVLGKKGHSFE-VDIWSI 228 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 G I++ LL G PF+ S L E Y +I K + P+ + A L+ ++L P +R T+D Sbjct: 229 GCIMYTLLVGKPPFETSCLKETYMRIKKNEYSVPKHINPMATALIQKMLRSEPTSRPTID 288 Query: 377 KLIEHPWFKKGYKPA 421 L+ +F GY P+ Sbjct: 289 DLLNDEFFTTGYIPS 303
>CHK1_CHICK (Q8AYC9) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 95.9 bits (237), Expect = 1e-19 Identities = 61/186 (32%), Positives = 94/186 (50%), Gaps = 19/186 (10%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+DE NLK+SDFGL+ + + ++ LL+ CGT YVAPE++ + + E D+W+C Sbjct: 135 NLLLDERDNLKISDFGLATVFKHNGRERLLNKMCGTLPYVAPELLRRPEFRAEPVDVWAC 194 Query: 197 GVILFVLLAGYLPF-QDSNLMEMYRKISKGDVRYPQWFSSDAR--KLLCRLLDPNPNTRI 367 GV+L +LAG LP+ Q S+ + Y + W D+ LL ++L NP RI Sbjct: 195 GVVLTAMLAGELPWDQPSDSCQEYSDWKERKTYLAPWRKIDSAPLALLHKILTENPTARI 254 Query: 368 TMDKLIEHPWF----KKGYK------------PAVMLGTPRASKDLNDVQAAFSTDHKDG 499 T+ + + W+ KKG K P + R+ D + V++A D Sbjct: 255 TIPDIKKDRWYCRPLKKGTKRGRVSSGGVTESPGALPKHIRSDTDFSPVKSALGEDKASY 314 Query: 500 EGSRAE 517 S+ E Sbjct: 315 STSQPE 320
>TSSK1_MOUSE (Q61241) Testis-specific serine/threonine-protein kinase 1 (EC| 2.7.11.1) (TSSK-1) (Testis-specific kinase 1) (TSK-1) (Serine/threonine-protein kinase 22A) Length = 364 Score = 95.9 bits (237), Expect = 1e-19 Identities = 58/176 (32%), Positives = 97/176 (55%), Gaps = 6/176 (3%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDG----LLHTTCGTPAYVAPEIINKKGYDGEKAD 184 NLL+D+ N+K+SDFG S K C + D L T CG+ AY APE++ Y + D Sbjct: 141 NLLLDKDFNIKLSDFGFS--KRCLRDDSGRLILSKTFCGSAAYAAPEVLQGIPYQPKVYD 198 Query: 185 IWSCGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYP--QWFSSDARKLLCRLLDPNPN 358 IWS GVIL++++ G +P+ DSN+ ++ R + V +P + + + + L+ R+L P+ N Sbjct: 199 IWSLGVILYIMVCGSMPYDDSNIKKL-RIQKEHRVNFPRSKHLTGECKDLIYRMLQPDVN 257 Query: 359 TRITMDKLIEHPWFKKGYKPAVMLGTPRASKDLNDVQAAFSTDHKDGEGSRAEQPN 526 R+ +D+++ H W + P+A + +K+GE SRA +P+ Sbjct: 258 RRLHIDEILNHCWVQ-----------PKAR------GLSSGAINKEGESSRATEPS 296
>KCC2G_MOUSE (Q923T9) Calcium/calmodulin-dependent protein kinase type II gamma| chain (EC 2.7.11.17) (CaM-kinase II gamma chain) (CaM kinase II gamma subunit) (CaMK-II gamma subunit) Length = 529 Score = 95.9 bits (237), Expect = 1e-19 Identities = 49/122 (40%), Positives = 77/122 (63%), Gaps = 4/122 (3%) Frame = +2 Query: 44 LKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSCGVILFVLLA 223 +K++DFGL+ E Q + GTP Y++PE++ K Y G+ DIW+CGVIL++LL Sbjct: 153 VKLADFGLAI--EVQGEQQAWFGFAGTPGYLSPEVLRKDPY-GKPVDIWACGVILYILLV 209 Query: 224 GYLPFQDSNLMEMYRKISKG--DVRYPQW--FSSDARKLLCRLLDPNPNTRITMDKLIEH 391 GY PF D + ++Y++I G D P+W + +A+ L+ ++L NP RIT D+ ++H Sbjct: 210 GYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKH 269 Query: 392 PW 397 PW Sbjct: 270 PW 271
>KCC2G_HUMAN (Q13555) Calcium/calmodulin-dependent protein kinase type II gamma| chain (EC 2.7.11.17) (CaM-kinase II gamma chain) (CaM kinase II gamma subunit) (CaMK-II gamma subunit) Length = 558 Score = 95.9 bits (237), Expect = 1e-19 Identities = 49/122 (40%), Positives = 77/122 (63%), Gaps = 4/122 (3%) Frame = +2 Query: 44 LKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSCGVILFVLLA 223 +K++DFGL+ E Q + GTP Y++PE++ K Y G+ DIW+CGVIL++LL Sbjct: 153 VKLADFGLAI--EVQGEQQAWFGFAGTPGYLSPEVLRKDPY-GKPVDIWACGVILYILLV 209 Query: 224 GYLPFQDSNLMEMYRKISKG--DVRYPQW--FSSDARKLLCRLLDPNPNTRITMDKLIEH 391 GY PF D + ++Y++I G D P+W + +A+ L+ ++L NP RIT D+ ++H Sbjct: 210 GYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKH 269 Query: 392 PW 397 PW Sbjct: 270 PW 271
>ASK1_ARATH (P43291) Serine/threonine-protein kinase ASK1 (EC 2.7.11.1)| Length = 363 Score = 95.9 bits (237), Expect = 1e-19 Identities = 52/131 (39%), Positives = 76/131 (58%), Gaps = 10/131 (7%) Frame = +2 Query: 44 LKVSDFGLSALKECQKQDGLLHT----TCGTPAYVAPEIINKKGYDGEKADIWSCGVILF 211 LK+ DFG S + LLH+ T GTPAY+APE+++++ YDG+ AD+WSCGV L+ Sbjct: 139 LKICDFGYS-------KSSLLHSRPKSTVGTPAYIAPEVLSRREYDGKMADVWSCGVTLY 191 Query: 212 VLLAGYLPFQD----SNLMEMYRKISKGDVRYPQW--FSSDARKLLCRLLDPNPNTRITM 373 V+L G PF+D N + +KI + P + S D + LL R+ N RIT+ Sbjct: 192 VMLVGAYPFEDQEDPKNFRKTIQKIMAVQYKIPDYVHISQDCKNLLSRIFVANSLKRITI 251 Query: 374 DKLIEHPWFKK 406 ++ +H WF K Sbjct: 252 AEIKKHSWFLK 262
>DCAK2_MOUSE (Q6PGN3) Serine/threonine-protein kinase DCAMKL2 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 2) Length = 756 Score = 95.9 bits (237), Expect = 1e-19 Identities = 54/137 (39%), Positives = 83/137 (60%), Gaps = 10/137 (7%) Frame = +2 Query: 17 NLLVDEHGN----LKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKAD 184 NLLV E+ + LK+ DFGL+ + E G L+T CGTP YVAPEII + GY G K D Sbjct: 519 NLLVCEYPDGTKSLKLGDFGLATVVE-----GPLYTVCGTPTYVAPEIIAETGY-GLKVD 572 Query: 185 IWSCGVILFVLLAGYLPFQDSNLM--EMYRKISKGDVRY--PQW--FSSDARKLLCRLLD 346 +W+ GVI ++LL G+ PF+ N + +++ +I G + + P W + A++L+ ++L Sbjct: 573 VWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQMLQ 632 Query: 347 PNPNTRITMDKLIEHPW 397 N R T +++ HPW Sbjct: 633 VNVEARCTAGEILSHPW 649
>KCC2G_RAT (P11730) Calcium/calmodulin-dependent protein kinase type II gamma| chain (EC 2.7.11.17) (CaM-kinase II gamma chain) (CaM kinase II gamma subunit) (CaMK-II gamma subunit) Length = 527 Score = 95.9 bits (237), Expect = 1e-19 Identities = 49/122 (40%), Positives = 77/122 (63%), Gaps = 4/122 (3%) Frame = +2 Query: 44 LKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSCGVILFVLLA 223 +K++DFGL+ E Q + GTP Y++PE++ K Y G+ DIW+CGVIL++LL Sbjct: 153 VKLADFGLAI--EVQGEQQAWFGFAGTPGYLSPEVLRKDPY-GKPVDIWACGVILYILLV 209 Query: 224 GYLPFQDSNLMEMYRKISKG--DVRYPQW--FSSDARKLLCRLLDPNPNTRITMDKLIEH 391 GY PF D + ++Y++I G D P+W + +A+ L+ ++L NP RIT D+ ++H Sbjct: 210 GYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKH 269 Query: 392 PW 397 PW Sbjct: 270 PW 271
>PHKG2_MOUSE (Q9DB30) Phosphorylase b kinase gamma catalytic chain, testis/liver| isoform (EC 2.7.11.19) (PHK-gamma-T) (Phosphorylase kinase gamma subunit 2) Length = 406 Score = 95.9 bits (237), Expect = 1e-19 Identities = 52/140 (37%), Positives = 85/140 (60%), Gaps = 10/140 (7%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIIN------KKGYDGEK 178 N+L+D++ +++SDFG S E ++ L CGTP Y+APEI+ GY G++ Sbjct: 158 NILLDDNMQIRLSDFGFSCHLEAGEK---LRELCGTPGYLAPEILKCSMDETHPGY-GKE 213 Query: 179 ADIWSCGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRY--PQW--FSSDARKLLCRLLD 346 D+W+CGVILF LLAG PF + M R I +G ++ P+W S+ + L+ +LL Sbjct: 214 VDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFTSPEWDDCSNTVKDLISKLLQ 273 Query: 347 PNPNTRITMDKLIEHPWFKK 406 +P R+T ++ ++HP+F++ Sbjct: 274 VDPEARLTAEQALQHPFFER 293
>KAPCA_SHEEP (Q9MZD9) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 95.5 bits (236), Expect = 1e-19 Identities = 52/133 (39%), Positives = 78/133 (58%), Gaps = 5/133 (3%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D+ G ++V+DFG + ++ G T CGTP Y+APEII KGY+ + D W+ Sbjct: 171 NLLIDQQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEIILSKGYN-KAVDWWAL 224 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPN-----PNT 361 GV+++ + AGY PF +++Y KI G VR+P FSSD + LL LL + N Sbjct: 225 GVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNL 284 Query: 362 RITMDKLIEHPWF 400 + ++ + H WF Sbjct: 285 KNGVNDIKNHKWF 297
>KAPCA_RAT (P27791) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 95.5 bits (236), Expect = 1e-19 Identities = 52/133 (39%), Positives = 78/133 (58%), Gaps = 5/133 (3%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D+ G ++V+DFG + ++ G T CGTP Y+APEII KGY+ + D W+ Sbjct: 171 NLLIDQQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEIILSKGYN-KAVDWWAL 224 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPN-----PNT 361 GV+++ + AGY PF +++Y KI G VR+P FSSD + LL LL + N Sbjct: 225 GVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNL 284 Query: 362 RITMDKLIEHPWF 400 + ++ + H WF Sbjct: 285 KNGVNDIKNHKWF 297
>KAPCA_PIG (P36887) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 95.5 bits (236), Expect = 1e-19 Identities = 52/133 (39%), Positives = 78/133 (58%), Gaps = 5/133 (3%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D+ G ++V+DFG + ++ G T CGTP Y+APEII KGY+ + D W+ Sbjct: 171 NLLIDQQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEIILSKGYN-KAVDWWAL 224 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPN-----PNT 361 GV+++ + AGY PF +++Y KI G VR+P FSSD + LL LL + N Sbjct: 225 GVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNL 284 Query: 362 RITMDKLIEHPWF 400 + ++ + H WF Sbjct: 285 KNGVNDIKNHKWF 297
>KAPCA_MOUSE (P05132) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 95.5 bits (236), Expect = 1e-19 Identities = 52/133 (39%), Positives = 78/133 (58%), Gaps = 5/133 (3%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D+ G ++V+DFG + ++ G T CGTP Y+APEII KGY+ + D W+ Sbjct: 171 NLLIDQQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEIILSKGYN-KAVDWWAL 224 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPN-----PNT 361 GV+++ + AGY PF +++Y KI G VR+P FSSD + LL LL + N Sbjct: 225 GVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNL 284 Query: 362 RITMDKLIEHPWF 400 + ++ + H WF Sbjct: 285 KNGVNDIKNHKWF 297
>KAPCA_HUMAN (P17612) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 95.5 bits (236), Expect = 1e-19 Identities = 52/133 (39%), Positives = 78/133 (58%), Gaps = 5/133 (3%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D+ G ++V+DFG + ++ G T CGTP Y+APEII KGY+ + D W+ Sbjct: 171 NLLIDQQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEIILSKGYN-KAVDWWAL 224 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPN-----PNT 361 GV+++ + AGY PF +++Y KI G VR+P FSSD + LL LL + N Sbjct: 225 GVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNL 284 Query: 362 RITMDKLIEHPWF 400 + ++ + H WF Sbjct: 285 KNGVNDIKNHKWF 297
>KAPCA_CRIGR (P25321) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 95.5 bits (236), Expect = 1e-19 Identities = 52/133 (39%), Positives = 78/133 (58%), Gaps = 5/133 (3%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D+ G ++V+DFG + ++ G T CGTP Y+APEII KGY+ + D W+ Sbjct: 171 NLLIDQQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEIILSKGYN-KAVDWWAL 224 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPN-----PNT 361 GV+++ + AGY PF +++Y KI G VR+P FSSD + LL LL + N Sbjct: 225 GVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNL 284 Query: 362 RITMDKLIEHPWF 400 + ++ + H WF Sbjct: 285 KNGVNDIKNHKWF 297
>KAPCA_BOVIN (P00517) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 95.5 bits (236), Expect = 1e-19 Identities = 52/133 (39%), Positives = 78/133 (58%), Gaps = 5/133 (3%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D+ G ++V+DFG + ++ G T CGTP Y+APEII KGY+ + D W+ Sbjct: 171 NLLIDQQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEIILSKGYN-KAVDWWAL 224 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPN-----PNT 361 GV+++ + AGY PF +++Y KI G VR+P FSSD + LL LL + N Sbjct: 225 GVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNL 284 Query: 362 RITMDKLIEHPWF 400 + ++ + H WF Sbjct: 285 KNGVNDIKNHKWF 297
>KCC2A_DROME (Q00168) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) Length = 530 Score = 95.5 bits (236), Expect = 1e-19 Identities = 49/122 (40%), Positives = 75/122 (61%), Gaps = 4/122 (3%) Frame = +2 Query: 44 LKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSCGVILFVLLA 223 +K++DFGL+ E Q GTP Y++PE++ K+ Y G+ DIW+CGVIL++LL Sbjct: 153 VKLADFGLAI--EVQGDHQAWFGFAGTPGYLSPEVLKKEPY-GKSVDIWACGVILYILLV 209 Query: 224 GYLPFQDSNLMEMYRKISKGDVRY--PQW--FSSDARKLLCRLLDPNPNTRITMDKLIEH 391 GY PF D + +Y +I G Y P+W + +A+ L+ ++L NPN RIT + ++H Sbjct: 210 GYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKRITAAEALKH 269 Query: 392 PW 397 PW Sbjct: 270 PW 271
>PHKG1_RABIT (P00518) Phosphorylase b kinase gamma catalytic chain, skeletal| muscle isoform (EC 2.7.11.19) (Phosphorylase kinase gamma subunit 1) Length = 386 Score = 95.5 bits (236), Expect = 1e-19 Identities = 59/153 (38%), Positives = 86/153 (56%), Gaps = 11/153 (7%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDG-LLHTTCGTPAYVAPEII------NKKGYDGE 175 N+L+D+ N+K++DFG S CQ G L CGTP+Y+APEII N GY G+ Sbjct: 154 NILLDDDMNIKLTDFGFS----CQLDPGEKLREVCGTPSYLAPEIIECSMNDNHPGY-GK 208 Query: 176 KADIWSCGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRY--PQW--FSSDARKLLCRLL 343 + D+WS GVI++ LLAG PF M M R I G+ ++ P+W +S + L+ R L Sbjct: 209 EVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSDTVKDLVSRFL 268 Query: 344 DPNPNTRITMDKLIEHPWFKKGYKPAVMLGTPR 442 P R T ++ + HP+F++ V +PR Sbjct: 269 VVQPQKRYTAEEALAHPFFQQYVVEEVRHFSPR 301
>PHKG1_HUMAN (Q16816) Phosphorylase b kinase gamma catalytic chain, skeletal| muscle isoform (EC 2.7.11.19) (Phosphorylase kinase gamma subunit 1) Length = 386 Score = 95.5 bits (236), Expect = 1e-19 Identities = 58/153 (37%), Positives = 88/153 (57%), Gaps = 11/153 (7%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDG-LLHTTCGTPAYVAPEII------NKKGYDGE 175 N+L+D++ N+K++DFG S CQ + G L CGTP+Y+APEII + GY G+ Sbjct: 154 NILLDDNMNIKLTDFGFS----CQLEPGERLREVCGTPSYLAPEIIECSMNEDHPGY-GK 208 Query: 176 KADIWSCGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRY--PQW--FSSDARKLLCRLL 343 + D+WS GVI++ LLAG PF M M R I G+ ++ P+W +S + L+ R L Sbjct: 209 EVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSDTVKDLVSRFL 268 Query: 344 DPNPNTRITMDKLIEHPWFKKGYKPAVMLGTPR 442 P R T ++ + HP+F++ V +PR Sbjct: 269 VVQPQNRYTAEEALAHPFFQQYLVEEVRHFSPR 301
>CHK1_MOUSE (O35280) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 95.5 bits (236), Expect = 1e-19 Identities = 50/133 (37%), Positives = 77/133 (57%), Gaps = 3/133 (2%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+DE NLK+SDFGL+ + ++ LL+ CGT YVAPE++ +K + E D+WSC Sbjct: 135 NLLLDERDNLKISDFGLATVFRHNNRERLLNKMCGTLPYVAPELLKRKEFHAEPVDVWSC 194 Query: 197 GVILFVLLAGYLPF-QDSNLMEMYRKISKGDVRYPQWFSSDAR--KLLCRLLDPNPNTRI 367 G++L +LAG LP+ Q S+ + Y + W D+ LL ++L P+ RI Sbjct: 195 GIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVETPSARI 254 Query: 368 TMDKLIEHPWFKK 406 T+ + + W+ K Sbjct: 255 TIPDIKKDRWYNK 267
>SN1L2_PONPY (Q5REX1) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) Length = 925 Score = 95.5 bits (236), Expect = 1e-19 Identities = 48/127 (37%), Positives = 75/127 (59%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D + N+K++DF K LL T G+P Y APE+ + Y+G + DIWS Sbjct: 147 NLLLDNNMNIKIADFSFGNFF---KSGELLATWRGSPPYAAPEVFEGQQYEGPQLDIWSM 203 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 GV+L+VL+ G LPF L + +++ +G R P + S D L+ R+L +P+ R+T+ Sbjct: 204 GVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPSKRLTIA 263 Query: 377 KLIEHPW 397 ++ EH W Sbjct: 264 QIKEHKW 270
>KAPCA_CANFA (Q8MJ44) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 349 Score = 95.5 bits (236), Expect = 1e-19 Identities = 52/133 (39%), Positives = 78/133 (58%), Gaps = 5/133 (3%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D+ G ++V+DFG + ++ G T CGTP Y+APEII KGY+ + D W+ Sbjct: 170 NLLIDQQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEIILSKGYN-KAVDWWAL 223 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPN-----PNT 361 GV+++ + AGY PF +++Y KI G VR+P FSSD + LL LL + N Sbjct: 224 GVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNL 283 Query: 362 RITMDKLIEHPWF 400 + ++ + H WF Sbjct: 284 KNGVNDIKNHKWF 296
>STK6_HUMAN (O14965) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1) (Aurora-related kinase 1) (hARK1) (Aurora-A) (Breast-tumor-amplified kinase) Length = 403 Score = 95.5 bits (236), Expect = 1e-19 Identities = 53/146 (36%), Positives = 81/146 (55%), Gaps = 1/146 (0%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+ G LK++DFG S ++ T CGT Y+ PE+I + +D EK D+WS Sbjct: 261 NLLLGSAGELKIADFGWSVHAPSSRRT----TLCGTLDYLPPEMIEGRMHD-EKVDLWSL 315 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 GV+ + L G PF+ + E Y++IS+ + +P + + AR L+ RLL NP+ R + Sbjct: 316 GVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLR 375 Query: 377 KLIEHPWF-KKGYKPAVMLGTPRASK 451 +++EHPW KP+ ASK Sbjct: 376 EVLEHPWITANSSKPSNCQNKESASK 401
>KS6A3_MOUSE (P18654) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B) Length = 740 Score = 94.7 bits (234), Expect = 2e-19 Identities = 68/212 (32%), Positives = 107/212 (50%), Gaps = 10/212 (4%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 N+L+DE G++K++DFGLS KE + ++ CGT Y+APE++N++G+ + AD WS Sbjct: 198 NILLDEEGHIKLTDFGLS--KESIDHEKKAYSFCGTVEYMAPEVVNRRGHT-QSADWWSF 254 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRI--- 367 GV++F +L G LPFQ + E I K + PQ+ S +A+ LL L NP R+ Sbjct: 255 GVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLRMLFKRNPANRLGAG 314 Query: 368 --TMDKLIEHPWF-----KKGYKPAVMLGTPRASKDLNDVQAAFSTDHKDGEGSRAEQPN 526 ++++ H +F K Y+ + A+ D T + D E + + Sbjct: 315 PDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPED------TFYFDPEFTAKTPKD 368 Query: 527 SPLKPASLNAFDIISLSKGFDLSGLFEKDQEQ 622 SP P S NA L +GF + D+ Q Sbjct: 369 SPGIPPSANAH---QLFRGFSFVAITSDDESQ 397 Score = 87.4 bits (215), Expect = 3e-17 Identities = 50/136 (36%), Positives = 77/136 (56%), Gaps = 10/136 (7%) Frame = +2 Query: 20 LLVDEHGN---LKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIW 190 L VDE GN +++ DFG + K+ + ++GLL T C T +VAPE++ ++GYD DIW Sbjct: 546 LYVDESGNPESIRICDFGFA--KQLRAENGLLMTPCYTANFVAPEVLKRQGYDA-ACDIW 602 Query: 191 SCGVILFVLLAGYLPF---QDSNLMEMYRKISKGDVR----YPQWFSSDARKLLCRLLDP 349 S GV+L+ +L GY PF D E+ +I G Y S A+ L+ ++L Sbjct: 603 SLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKMLHV 662 Query: 350 NPNTRITMDKLIEHPW 397 +P+ R+T ++ HPW Sbjct: 663 DPHQRLTAALVLRHPW 678
>KS6A3_HUMAN (P51812) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protei Length = 740 Score = 94.7 bits (234), Expect = 2e-19 Identities = 68/212 (32%), Positives = 107/212 (50%), Gaps = 10/212 (4%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 N+L+DE G++K++DFGLS KE + ++ CGT Y+APE++N++G+ + AD WS Sbjct: 198 NILLDEEGHIKLTDFGLS--KESIDHEKKAYSFCGTVEYMAPEVVNRRGHT-QSADWWSF 254 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRI--- 367 GV++F +L G LPFQ + E I K + PQ+ S +A+ LL L NP R+ Sbjct: 255 GVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLRMLFKRNPANRLGAG 314 Query: 368 --TMDKLIEHPWF-----KKGYKPAVMLGTPRASKDLNDVQAAFSTDHKDGEGSRAEQPN 526 ++++ H +F K Y+ + A+ D T + D E + + Sbjct: 315 PDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPED------TFYFDPEFTAKTPKD 368 Query: 527 SPLKPASLNAFDIISLSKGFDLSGLFEKDQEQ 622 SP P S NA L +GF + D+ Q Sbjct: 369 SPGIPPSANAH---QLFRGFSFVAITSDDESQ 397 Score = 87.4 bits (215), Expect = 3e-17 Identities = 50/136 (36%), Positives = 77/136 (56%), Gaps = 10/136 (7%) Frame = +2 Query: 20 LLVDEHGN---LKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIW 190 L VDE GN +++ DFG + K+ + ++GLL T C T +VAPE++ ++GYD DIW Sbjct: 546 LYVDESGNPESIRICDFGFA--KQLRAENGLLMTPCYTANFVAPEVLKRQGYDA-ACDIW 602 Query: 191 SCGVILFVLLAGYLPF---QDSNLMEMYRKISKGDVR----YPQWFSSDARKLLCRLLDP 349 S GV+L+ +L GY PF D E+ +I G Y S A+ L+ ++L Sbjct: 603 SLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKMLHV 662 Query: 350 NPNTRITMDKLIEHPW 397 +P+ R+T ++ HPW Sbjct: 663 DPHQRLTAALVLRHPW 678
>DCAK1_RAT (O08875) Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 1) (Calcium/calmodulin-dependent protein kinase type I-like CPG16) Length = 433 Score = 94.4 bits (233), Expect = 3e-19 Identities = 58/137 (42%), Positives = 83/137 (60%), Gaps = 10/137 (7%) Frame = +2 Query: 17 NLLVDEHGN----LKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKAD 184 NLLV EH + LK+ DFGL+ + DG L+T CGTP YVAPEII + GY G K D Sbjct: 209 NLLVYEHQDGSKSLKLGDFGLATIV-----DGPLYTVCGTPTYVAPEIIAETGY-GLKVD 262 Query: 185 IWSCGVILFVLLAGYLPFQDS--NLMEMYRKISKGDVRYPQ--W--FSSDARKLLCRLLD 346 IW+ GVI ++LL G+ PF+ S + ++ +I G V +P W S A++L+ +L Sbjct: 263 IWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELINMMLL 322 Query: 347 PNPNTRITMDKLIEHPW 397 N + R + +++EHPW Sbjct: 323 VNVDQRFSAVQVLEHPW 339
>DCAK1_MOUSE (Q9JLM8) Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 1) Length = 756 Score = 94.4 bits (233), Expect = 3e-19 Identities = 58/137 (42%), Positives = 83/137 (60%), Gaps = 10/137 (7%) Frame = +2 Query: 17 NLLVDEHGN----LKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKAD 184 NLLV EH + LK+ DFGL+ + DG L+T CGTP YVAPEII + GY G K D Sbjct: 532 NLLVYEHQDGSKSLKLGDFGLATIV-----DGPLYTVCGTPTYVAPEIIAETGY-GLKVD 585 Query: 185 IWSCGVILFVLLAGYLPFQDS--NLMEMYRKISKGDVRYPQ--W--FSSDARKLLCRLLD 346 IW+ GVI ++LL G+ PF+ S + ++ +I G V +P W S A++L+ +L Sbjct: 586 IWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELINMMLL 645 Query: 347 PNPNTRITMDKLIEHPW 397 N + R + +++EHPW Sbjct: 646 VNVDQRFSAVQVLEHPW 662
>KAPB2_BOVIN (P24256) cAMP-dependent protein kinase, beta-2-catalytic subunit| (EC 2.7.11.11) (PKA C-beta-2) Length = 397 Score = 94.0 bits (232), Expect = 4e-19 Identities = 52/133 (39%), Positives = 76/133 (57%), Gaps = 5/133 (3%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D G ++V+DFG + ++ G T CGTP Y+APEII KGY+ + D W+ Sbjct: 218 NLLIDHQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEIILSKGYN-KAVDWWAL 271 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPN-----PNT 361 GV+++ + AGY PF +++Y KI G VR+P FSSD + LL LL + N Sbjct: 272 GVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNL 331 Query: 362 RITMDKLIEHPWF 400 + + + H WF Sbjct: 332 KNGVSDIKTHKWF 344
>KAPCB_RAT (P68182) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 94.0 bits (232), Expect = 4e-19 Identities = 52/133 (39%), Positives = 76/133 (57%), Gaps = 5/133 (3%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D G ++V+DFG + ++ G T CGTP Y+APEII KGY+ + D W+ Sbjct: 171 NLLIDHQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEIILSKGYN-KAVDWWAL 224 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPN-----PNT 361 GV+++ + AGY PF +++Y KI G VR+P FSSD + LL LL + N Sbjct: 225 GVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNL 284 Query: 362 RITMDKLIEHPWF 400 + + + H WF Sbjct: 285 KNGVSDIKTHKWF 297
>KAPCB_PIG (P05383) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 94.0 bits (232), Expect = 4e-19 Identities = 52/133 (39%), Positives = 76/133 (57%), Gaps = 5/133 (3%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D G ++V+DFG + ++ G T CGTP Y+APEII KGY+ + D W+ Sbjct: 171 NLLIDHQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEIILSKGYN-KAVDWWAL 224 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPN-----PNT 361 GV+++ + AGY PF +++Y KI G VR+P FSSD + LL LL + N Sbjct: 225 GVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNL 284 Query: 362 RITMDKLIEHPWF 400 + + + H WF Sbjct: 285 KNGVSDIKTHKWF 297
>KAPCB_MOUSE (P68181) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 94.0 bits (232), Expect = 4e-19 Identities = 52/133 (39%), Positives = 76/133 (57%), Gaps = 5/133 (3%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D G ++V+DFG + ++ G T CGTP Y+APEII KGY+ + D W+ Sbjct: 171 NLLIDHQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEIILSKGYN-KAVDWWAL 224 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPN-----PNT 361 GV+++ + AGY PF +++Y KI G VR+P FSSD + LL LL + N Sbjct: 225 GVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNL 284 Query: 362 RITMDKLIEHPWF 400 + + + H WF Sbjct: 285 KNGVSDIKTHKWF 297
>KAPCB_HUMAN (P22694) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 94.0 bits (232), Expect = 4e-19 Identities = 52/133 (39%), Positives = 76/133 (57%), Gaps = 5/133 (3%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D G ++V+DFG + ++ G T CGTP Y+APEII KGY+ + D W+ Sbjct: 171 NLLIDHQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEIILSKGYN-KAVDWWAL 224 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPN-----PNT 361 GV+++ + AGY PF +++Y KI G VR+P FSSD + LL LL + N Sbjct: 225 GVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNL 284 Query: 362 RITMDKLIEHPWF 400 + + + H WF Sbjct: 285 KNGVSDIKTHKWF 297
>KAPCB_CRIGR (P68180) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 94.0 bits (232), Expect = 4e-19 Identities = 52/133 (39%), Positives = 76/133 (57%), Gaps = 5/133 (3%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D G ++V+DFG + ++ G T CGTP Y+APEII KGY+ + D W+ Sbjct: 171 NLLIDHQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEIILSKGYN-KAVDWWAL 224 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPN-----PNT 361 GV+++ + AGY PF +++Y KI G VR+P FSSD + LL LL + N Sbjct: 225 GVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNL 284 Query: 362 RITMDKLIEHPWF 400 + + + H WF Sbjct: 285 KNGVSDIKTHKWF 297
>KAPB1_BOVIN (P05131) cAMP-dependent protein kinase, beta-1-catalytic subunit| (EC 2.7.11.11) (PKA C-beta-1) Length = 350 Score = 94.0 bits (232), Expect = 4e-19 Identities = 52/133 (39%), Positives = 76/133 (57%), Gaps = 5/133 (3%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D G ++V+DFG + ++ G T CGTP Y+APEII KGY+ + D W+ Sbjct: 171 NLLIDHQGYIQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEIILSKGYN-KAVDWWAL 224 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPN-----PNT 361 GV+++ + AGY PF +++Y KI G VR+P FSSD + LL LL + N Sbjct: 225 GVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNL 284 Query: 362 RITMDKLIEHPWF 400 + + + H WF Sbjct: 285 KNGVSDIKTHKWF 297
>KCC2B_RAT (P08413) Calcium/calmodulin-dependent protein kinase type II beta| chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II beta subunit) (CaMK-II beta subunit) Length = 542 Score = 94.0 bits (232), Expect = 4e-19 Identities = 48/122 (39%), Positives = 76/122 (62%), Gaps = 4/122 (3%) Frame = +2 Query: 44 LKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSCGVILFVLLA 223 +K++DFGL+ E Q GTP Y++PE++ K+ Y G+ DIW+CGVIL++LL Sbjct: 153 VKLADFGLAI--EVQGDQQAWFGFAGTPGYLSPEVLRKEAY-GKPVDIWACGVILYILLV 209 Query: 224 GYLPFQDSNLMEMYRKISKG--DVRYPQW--FSSDARKLLCRLLDPNPNTRITMDKLIEH 391 GY PF D + ++Y++I G D P+W + +A+ L+ ++L NP RIT + ++H Sbjct: 210 GYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKH 269 Query: 392 PW 397 PW Sbjct: 270 PW 271
>KCC2B_MOUSE (P28652) Calcium/calmodulin-dependent protein kinase type II beta| chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II beta subunit) (CaMK-II beta subunit) Length = 542 Score = 94.0 bits (232), Expect = 4e-19 Identities = 48/122 (39%), Positives = 76/122 (62%), Gaps = 4/122 (3%) Frame = +2 Query: 44 LKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSCGVILFVLLA 223 +K++DFGL+ E Q GTP Y++PE++ K+ Y G+ DIW+CGVIL++LL Sbjct: 153 VKLADFGLAI--EVQGDQQAWFGFAGTPGYLSPEVLRKEAY-GKPVDIWACGVILYILLV 209 Query: 224 GYLPFQDSNLMEMYRKISKG--DVRYPQW--FSSDARKLLCRLLDPNPNTRITMDKLIEH 391 GY PF D + ++Y++I G D P+W + +A+ L+ ++L NP RIT + ++H Sbjct: 210 GYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKH 269 Query: 392 PW 397 PW Sbjct: 270 PW 271
>KPSH1_MOUSE (Q91YA2) Serine/threonine-protein kinase H1 (EC 2.7.11.1) (PSK-H1)| Length = 423 Score = 94.0 bits (232), Expect = 4e-19 Identities = 47/120 (39%), Positives = 76/120 (63%), Gaps = 4/120 (3%) Frame = +2 Query: 50 VSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSCGVILFVLLAGY 229 ++DFGL++ ++ + D L+ TTCGTP Y+APE++ +K Y D+W+ GVI ++LL+G Sbjct: 236 ITDFGLASARK-KGDDCLMKTTCGTPEYIAPEVLVRKPYTNS-VDMWALGVIAYILLSGT 293 Query: 230 LPFQDSNLMEMYRKISKGDVRY--PQW--FSSDARKLLCRLLDPNPNTRITMDKLIEHPW 397 +PF+D N +YR+I +G Y W S+ A+ + RLL +P R+T + + HPW Sbjct: 294 MPFEDDNRTRLYRQILRGKYSYLGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPW 353
>KPSH1_HUMAN (P11801) Serine/threonine-protein kinase H1 (EC 2.7.11.1) (PSK-H1)| Length = 423 Score = 94.0 bits (232), Expect = 4e-19 Identities = 47/120 (39%), Positives = 76/120 (63%), Gaps = 4/120 (3%) Frame = +2 Query: 50 VSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSCGVILFVLLAGY 229 ++DFGL++ ++ + D L+ TTCGTP Y+APE++ +K Y D+W+ GVI ++LL+G Sbjct: 236 ITDFGLASARK-KGDDCLMKTTCGTPEYIAPEVLVRKPYTNS-VDMWALGVIAYILLSGT 293 Query: 230 LPFQDSNLMEMYRKISKGDVRY--PQW--FSSDARKLLCRLLDPNPNTRITMDKLIEHPW 397 +PF+D N +YR+I +G Y W S+ A+ + RLL +P R+T + + HPW Sbjct: 294 MPFEDDNRTRLYRQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPW 353
>KPC3_DROME (P13678) Protein kinase C (EC 2.7.11.13) (PKC) (dPKC98F)| Length = 634 Score = 94.0 bits (232), Expect = 4e-19 Identities = 51/137 (37%), Positives = 83/137 (60%), Gaps = 7/137 (5%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQK--QDGLLHTT-CGTPAYVAPEIINKKGYDGEKADI 187 N+L+D+ G+ K++DFG+ C++ +G+L TT CGTP Y+APEI+ ++ Y G D Sbjct: 432 NILLDQEGHCKLADFGM-----CKEGIMNGMLTTTFCGTPDYIAPEILKEQEY-GASVDW 485 Query: 188 WSCGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRI 367 W+ GV+++ ++AG PF+ N E++ I DV YP W S +A +L L NP R+ Sbjct: 486 WALGVLMYEMMAGQPPFEADNEDELFDSIMHDDVLYPVWLSREAVSILKGFLTKNPEQRL 545 Query: 368 ----TMDKLIEHPWFKK 406 +++ +HP+F K Sbjct: 546 GCTGDENEIRKHPFFAK 562
>KCC2B_HUMAN (Q13554) Calcium/calmodulin-dependent protein kinase type II beta| chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II beta subunit) (CaMK-II beta subunit) Length = 664 Score = 94.0 bits (232), Expect = 4e-19 Identities = 48/122 (39%), Positives = 76/122 (62%), Gaps = 4/122 (3%) Frame = +2 Query: 44 LKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSCGVILFVLLA 223 +K++DFGL+ E Q GTP Y++PE++ K+ Y G+ DIW+CGVIL++LL Sbjct: 153 VKLADFGLAI--EVQGDQQAWFGFAGTPGYLSPEVLRKEAY-GKPVDIWACGVILYILLV 209 Query: 224 GYLPFQDSNLMEMYRKISKG--DVRYPQW--FSSDARKLLCRLLDPNPNTRITMDKLIEH 391 GY PF D + ++Y++I G D P+W + +A+ L+ ++L NP RIT + ++H Sbjct: 210 GYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKH 269 Query: 392 PW 397 PW Sbjct: 270 PW 271
>KS6AA_CHICK (P18652) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 752 Score = 93.6 bits (231), Expect = 5e-19 Identities = 55/154 (35%), Positives = 86/154 (55%), Gaps = 18/154 (11%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 N+L+DE G++K++DFGLS KE + ++ CGT Y+APE++N++G+ AD WS Sbjct: 210 NILLDEEGHIKLTDFGLS--KEAIDHEKKAYSFCGTVEYMAPEVVNRQGHS-HSADWWSY 266 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRI--- 367 GV++F +L G LPFQ + E I K + PQ+ S++A+ LL L NP R+ Sbjct: 267 GVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSAEAQSLLRALFKRNPANRLGSG 326 Query: 368 --TMDKLIEHPWF-------------KKGYKPAV 424 +++ HP++ K +KPAV Sbjct: 327 PDGAEEIKRHPFYSTIDWNKLYRREIKPPFKPAV 360 Score = 90.1 bits (222), Expect = 5e-18 Identities = 60/184 (32%), Positives = 99/184 (53%), Gaps = 10/184 (5%) Frame = +2 Query: 20 LLVDEHGN---LKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIW 190 L VDE GN +++ DFG + K+ + ++GLL T C T +VAPE++ ++GYD E DIW Sbjct: 559 LYVDESGNPESIRICDFGFA--KQLRAENGLLMTPCYTANFVAPEVLKRQGYD-EGCDIW 615 Query: 191 SCGVILFVLLAGYLPFQD---SNLMEMYRKISKG--DVRYPQW--FSSDARKLLCRLLDP 349 S GV+L+ +LAG PF + E+ +I G V W S A+ L+ ++L Sbjct: 616 SLGVLLYTMLAGCTPFANGPSDTPEEILTRIGGGKFSVNGGNWDTISDVAKDLVSKMLHV 675 Query: 350 NPNTRITMDKLIEHPWFKKGYKPAVMLGTPRASKDLNDVQAAFSTDHKDGEGSRAEQPNS 529 +P+ R+T ++++HPW + K ++ P++ + DVQ + +P+ Sbjct: 676 DPHQRLTAKQVLQHPWITQ--KDSL----PQSQLNYQDVQLVKGAMAATYSALNSSKPSP 729 Query: 530 PLKP 541 LKP Sbjct: 730 QLKP 733
>ARK1_SCHPO (O59790) Serine/threonine-protein kinase ark1 (EC 2.7.11.1)| (Aurora-related kinase 1) Length = 355 Score = 93.6 bits (231), Expect = 5e-19 Identities = 49/131 (37%), Positives = 77/131 (58%), Gaps = 1/131 (0%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 N+L+ G +K+SDFG S ++ T CGT Y+ PE++ K + EK D+WS Sbjct: 217 NILLGIDGEIKLSDFGWSVHAPSNRRT----TLCGTLDYLPPEMVEGKEHT-EKVDLWSL 271 Query: 197 GVILFVLLAGYLPFQD-SNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITM 373 GV+ + L G PF+D S Y++I+K D++ P + DAR L+ RLL NP R+++ Sbjct: 272 GVLTYEFLVGAPPFEDMSGHSATYKRIAKVDLKIPSFVPPDARDLISRLLQHNPEKRMSL 331 Query: 374 DKLIEHPWFKK 406 ++++ HPW K Sbjct: 332 EQVMRHPWIVK 342
>KS6A1_RAT (Q63531) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1) (S6K-alpha| 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 93.6 bits (231), Expect = 5e-19 Identities = 64/185 (34%), Positives = 100/185 (54%), Gaps = 11/185 (5%) Frame = +2 Query: 20 LLVDEHGN---LKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIW 190 L VDE GN L++ DFG + K+ + ++GLL T C T +VAPE++ ++GYD E DIW Sbjct: 542 LYVDESGNPECLRICDFGFA--KQLRAENGLLMTPCYTANFVAPEVLKRQGYD-EGCDIW 598 Query: 191 SCGVILFVLLAGYLPFQD---SNLMEMYRKISKGDVRYP--QW--FSSDARKLLCRLLDP 349 S GV+L+ +LAGY PF + E+ +IS G W S A+ L+ ++L Sbjct: 599 SLGVLLYTMLAGYTPFANGPSDTPEEILTRISSGKFTLSGGNWNTVSETAKDLVSKMLHV 658 Query: 350 NPNTRITMDKLIEHPWF-KKGYKPAVMLGTPRASKDLNDVQAAFSTDHKDGEGSRAEQPN 526 +P+ R+T ++++HPW +K P L + +DL V+ + + S+ P Sbjct: 659 DPHQRLTAKQVLQHPWITQKDKLPQSQL----SHQDLQLVKGGMAATYSALSSSK---PT 711 Query: 527 SPLKP 541 LKP Sbjct: 712 PQLKP 716 Score = 93.6 bits (231), Expect = 5e-19 Identities = 75/238 (31%), Positives = 116/238 (48%), Gaps = 20/238 (8%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 N+L+DE G++K++DFGLS KE + ++ CGT Y+APE++N++G+ AD WS Sbjct: 192 NILLDEEGHIKLTDFGLS--KEAIDHEKKAYSFCGTVEYMAPEVVNRQGHT-HSADWWSY 248 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRI--- 367 GV++F +L G LPFQ + E I K + PQ+ S++A+ LL L NP R+ Sbjct: 249 GVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSTEAQSLLRALFKRNPANRLGSG 308 Query: 368 --TMDKLIEHPWF-------------KKGYKPAVMLGTPRASKDLNDVQAAFSTDHKDGE 502 +++ H ++ K +KPAV A D T + D E Sbjct: 309 PDGAEEIKRHIFYSTIDWNKLYRREIKPPFKPAV------AQPD--------DTFYFDTE 354 Query: 503 GSRAEQPNSPLKPASLNAFDIISLSKGFDL--SGLFEKDQEQKSNSRFMTQKPASAIV 670 + +SP P S A L +GF +GL E D + ++ TQ P ++V Sbjct: 355 FTSRTPRDSPGIPPSAGAH---QLFRGFSFVATGLMEDDSKPRA-----TQAPLHSVV 404
>KS6A_CAEEL (Q21734) Putative ribosomal protein S6 kinase alpha (EC 2.7.11.1)| Length = 784 Score = 93.6 bits (231), Expect = 5e-19 Identities = 60/188 (31%), Positives = 98/188 (52%), Gaps = 5/188 (2%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 N+L+D G++KV+DFGLS KE + ++ CGT Y+APE+IN++G+ AD WS Sbjct: 234 NILLDADGHIKVTDFGLS--KEAIDSEKKTYSFCGTVEYMAPEVINRRGHS-MAADFWSL 290 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRI--- 367 GV++F +L G+LPFQ + + +I K + P + + +A+ LL L N R+ Sbjct: 291 GVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMPHFLTQEAQSLLRALFKRNSQNRLGAG 350 Query: 368 --TMDKLIEHPWFKKGYKPAVMLGTPRASKDLNDVQAAFSTDHKDGEGSRAEQPNSPLKP 541 ++++ H +F K +L + ST + D E ++ +SP P Sbjct: 351 PDGVEEIKRHAFFAK-IDFVKLLNKEIDPPFKPALSTVDSTSYFDPEFTKRTPKDSPALP 409 Query: 542 ASLNAFDI 565 AS N +I Sbjct: 410 ASANGHEI 417 Score = 86.7 bits (213), Expect = 6e-17 Identities = 52/181 (28%), Positives = 96/181 (53%), Gaps = 9/181 (4%) Frame = +2 Query: 41 NLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSCGVILFVLL 220 +L++ DFG + K+ + ++G+L T C T +VAPE++ K+GYD D+WS GV+L +L Sbjct: 589 SLRIVDFGFA--KQSRAENGMLMTPCYTAQFVAPEVLRKQGYD-RSCDVWSLGVLLHTML 645 Query: 221 AGYLPF---QDSNLMEMYRKISKGDV--RYPQW--FSSDARKLLCRLLDPNPNTRITMDK 379 G PF + ++ +++ G + +P W S +A+ L+ ++LD +PN R+T + Sbjct: 646 TGCTPFAMGPNDTPDQILQRVGDGKISMTHPVWDTISDEAKDLVRKMLDVDPNRRVTAKQ 705 Query: 380 LIEHPWF--KKGYKPAVMLGTPRASKDLNDVQAAFSTDHKDGEGSRAEQPNSPLKPASLN 553 ++H W K+ + D+ +V+ A +K + A P+ L+P + Sbjct: 706 ALQHKWIGQKEALPDRPIQSEQVGELDMQNVKVALEQTYK----AIASAPSVQLRPVGSS 761 Query: 554 A 556 A Sbjct: 762 A 762
>PLK3_CAEEL (Q20845) Serine/threonine-protein kinase plk-3 (EC 2.7.11.21)| (Polo-like kinase 3) Length = 615 Score = 93.6 bits (231), Expect = 5e-19 Identities = 52/134 (38%), Positives = 79/134 (58%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NL ++EH +K+ DFGL+ C+K + + T GTP Y+APE++N+ G+ E DIW+ Sbjct: 163 NLFLNEHLQVKIGDFGLATF--CEKNEKKM-TRGGTPNYIAPEVLNETGHAFE-VDIWAI 218 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 G IL+VLL G PF+ + E Y +I D P+ S A +L+ LLDP P+ R T + Sbjct: 219 GCILYVLLFGSPPFESRRVQETYVRIKNNDYVVPENASPTANRLIRSLLDPVPDRRPTAE 278 Query: 377 KLIEHPWFKKGYKP 418 ++ +FK +P Sbjct: 279 AVLLDQFFKTTIEP 292
>CHK1_SCHPO (P34208) Serine/threonine-protein kinase chk1 (EC 2.7.11.1)| (Checkpoint kinase 1) Length = 496 Score = 93.2 bits (230), Expect = 6e-19 Identities = 70/224 (31%), Positives = 113/224 (50%), Gaps = 25/224 (11%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 N+L+D +GNLK+SDFG ++L + + LL++ G+P Y APEI + YDG K D+WSC Sbjct: 142 NILLDYNGNLKISDFGFASLFSYKGKSRLLNSPVGSPPYAAPEITQQ--YDGSKVDVWSC 199 Query: 197 GVILFVLLAGYLPFQD--SNLME--MYRKISKGDVRYP-QWFSSDARKLLCRLLDPNPNT 361 G+ILF LL G P+ + SN + +Y+K + +P S A ++ +L +P Sbjct: 200 GIILFALLLGNTPWDEAISNTGDYLLYKKQCERPSYHPWNLLSPGAYSIITGMLRSDPFK 259 Query: 362 RITMDKLIEHPWF--------KKG-YKPAVMLGTPRASK---DLNDVQAAFSTDHKDGEG 505 R ++ +++HPW K G V L + K DL+ + A S ++ G Sbjct: 260 RYSVKHVVQHPWLTSSTPFRTKNGNCADPVALASRLMLKLRIDLDKPRLASSRASQNDSG 319 Query: 506 SRAEQP----NSPLKPASLNAFDIIS----LSKGFDLSGLFEKD 613 QP N + + + +S L+K D++ + EKD Sbjct: 320 FSMTQPAFKKNDQKELDRVEVYGALSQPVQLNKNIDVTEILEKD 363
>KS6AA_XENLA (P10665) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 733 Score = 93.2 bits (230), Expect = 6e-19 Identities = 48/117 (41%), Positives = 73/117 (62%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 N+L+DE G++K++DFGLS KE + ++ CGT Y+APE++N++G+ AD WS Sbjct: 192 NILLDEEGHIKLTDFGLS--KEAIDHEKKAYSFCGTVEYMAPEVVNRQGHS-HSADWWSY 248 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRI 367 GV++F +L G LPFQ + E I K + PQ+ S++A+ LL L NP R+ Sbjct: 249 GVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSNEAQSLLRALFKRNPTNRL 305 Score = 89.0 bits (219), Expect = 1e-17 Identities = 60/188 (31%), Positives = 102/188 (54%), Gaps = 11/188 (5%) Frame = +2 Query: 20 LLVDEHGN---LKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIW 190 L VDE G+ +++ DFG + K+ + +GLL T C T +VAPE++ ++GYD E DIW Sbjct: 540 LYVDESGDPESIRICDFGFA--KQLRADNGLLMTPCYTANFVAPEVLKRQGYD-EGCDIW 596 Query: 191 SCGVILFVLLAGYLPFQD---SNLMEMYRKISKG--DVRYPQW--FSSDARKLLCRLLDP 349 S G++L+ +LAGY PF + E+ +I G +R W S+ A+ L+ R+L Sbjct: 597 SLGILLYTMLAGYTPFANGLGDTPEEILARIGSGKFTLRGGNWNTVSAAAKDLVSRMLHV 656 Query: 350 NPNTRITMDKLIEHPWF-KKGYKPAVMLGTPRASKDLNDVQAAFSTDHKDGEGSRAEQPN 526 +P+ R+T ++++H W K+ P L +D++ V+ A + + S+ Sbjct: 657 DPHKRLTAKQVLQHEWITKRDALPQSQLN----RQDVHLVKGAMAATYSALNSSKPTPLL 712 Query: 527 SPLKPASL 550 P+K + L Sbjct: 713 QPIKSSIL 720
>PHKG1_RAT (P13286) Phosphorylase b kinase gamma catalytic chain, skeletal| muscle isoform (EC 2.7.11.19) (Phosphorylase kinase gamma subunit 1) Length = 387 Score = 93.2 bits (230), Expect = 6e-19 Identities = 58/153 (37%), Positives = 86/153 (56%), Gaps = 11/153 (7%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDG-LLHTTCGTPAYVAPEIIN------KKGYDGE 175 N+L+D++ N+K++DFG S CQ Q G L CGTP+Y+APEII GY G+ Sbjct: 154 NILLDDNMNIKLTDFGFS----CQLQPGEKLREVCGTPSYLAPEIIQCSMDEGHPGY-GK 208 Query: 176 KADIWSCGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRY--PQW--FSSDARKLLCRLL 343 + D+WS GVI++ LLAG PF M M R I G ++ P+W +S + L+ R L Sbjct: 209 EVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMDGKYQFGSPEWDDYSDTVKDLVSRFL 268 Query: 344 DPNPNTRITMDKLIEHPWFKKGYKPAVMLGTPR 442 P R + ++ + HP+F++ V +PR Sbjct: 269 VVQPQDRCSAEEALAHPFFQEYVVEEVRHFSPR 301
>PHKG1_MOUSE (P07934) Phosphorylase b kinase gamma catalytic chain, skeletal| muscle isoform (EC 2.7.11.19) (Phosphorylase kinase gamma subunit 1) Length = 387 Score = 93.2 bits (230), Expect = 6e-19 Identities = 58/153 (37%), Positives = 86/153 (56%), Gaps = 11/153 (7%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDG-LLHTTCGTPAYVAPEIIN------KKGYDGE 175 N+L+D++ N+K++DFG S CQ Q G L CGTP+Y+APEII GY G+ Sbjct: 154 NILLDDNMNIKLTDFGFS----CQLQPGEKLREVCGTPSYLAPEIIQCSMDDGHPGY-GK 208 Query: 176 KADIWSCGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRY--PQW--FSSDARKLLCRLL 343 + D+WS GVI++ LLAG PF M M R I G ++ P+W +S + L+ R L Sbjct: 209 EVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMDGKYQFGSPEWDDYSDTVKDLVSRFL 268 Query: 344 DPNPNTRITMDKLIEHPWFKKGYKPAVMLGTPR 442 P R + ++ + HP+F++ V +PR Sbjct: 269 VVQPQDRCSAEEALAHPFFQEYVVEEVRHFSPR 301
>POLO_DROME (P52304) Serine/threonine-protein kinase polo (EC 2.7.11.21)| Length = 576 Score = 93.2 bits (230), Expect = 6e-19 Identities = 51/138 (36%), Positives = 78/138 (56%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NL +++ ++K+ DFGL+ E + + T CGTP Y+APEI+ KKG+ E DIWS Sbjct: 153 NLFLNDLLHVKIGDFGLATRIEYEGERK--KTLCGTPNYIAPEILTKKGHSFE-VDIWSI 209 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 G +++ LL G PF+ L + Y KI K + R P + A ++ +L PNP +R + Sbjct: 210 GCVMYTLLVGQPPFETKTLKDTYSKIKKCEYRVPSYLRKPAADMVIAMLQPNPESRPAIG 269 Query: 377 KLIEHPWFKKGYKPAVML 430 +L+ F KG K + L Sbjct: 270 QLLNFE-FLKGSKVPMFL 286
>CHK1_USTMA (P0C198) Serine/threonine-protein kinase CHK1 (EC 2.7.11.1)| (Checkpoint kinase 1) Length = 662 Score = 93.2 bits (230), Expect = 6e-19 Identities = 50/134 (37%), Positives = 77/134 (57%), Gaps = 4/134 (2%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 N+L+D GNLK++DFGL ++ + + ++ L CG+ Y+APE +N K Y GE D+WS Sbjct: 198 NMLLDAEGNLKIADFGLCSVYKYKGKERELTGACGSLPYIAPE-MNGKPYRGEPVDVWSS 256 Query: 197 GVILFVLLAGYLPFQD-SNLMEMYRKISKGDV-RYPQW--FSSDARKLLCRLLDPNPNTR 364 GV+LF +L G P+ + ++ Y G + Y W DA LL +++ P P R Sbjct: 257 GVVLFAMLVGSTPWDEPTSRSPEYSAYRTGKLFEYDPWPRIPQDALSLLKKMMHPTPEKR 316 Query: 365 ITMDKLIEHPWFKK 406 IT + + H WFK+ Sbjct: 317 ITFEGIRRHRWFKR 330
>KS6A1_MOUSE (P18653) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1) (S6K-alpha| 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 724 Score = 93.2 bits (230), Expect = 6e-19 Identities = 62/185 (33%), Positives = 100/185 (54%), Gaps = 11/185 (5%) Frame = +2 Query: 20 LLVDEHGN---LKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIW 190 L VDE GN L++ DFG + K+ + ++GLL T C T +VAPE++ ++GYD E DIW Sbjct: 531 LYVDESGNPECLRICDFGFA--KQLRAENGLLMTPCYTANFVAPEVLKRQGYD-EGCDIW 587 Query: 191 SCGVILFVLLAGYLPFQD---SNLMEMYRKISKGDVRYP--QW--FSSDARKLLCRLLDP 349 S G++L+ +LAGY PF + E+ +I G W S A+ L+ ++L Sbjct: 588 SLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTLSGGNWNTVSETAKDLVSKMLHV 647 Query: 350 NPNTRITMDKLIEHPWF-KKGYKPAVMLGTPRASKDLNDVQAAFSTDHKDGEGSRAEQPN 526 +P+ R+T ++++HPW +K P L + +DL V+ A + + + +P Sbjct: 648 DPHQRLTAKQVLQHPWITQKDKLPQSQL----SHQDLQLVKGAMAATY---SALNSSKPT 700 Query: 527 SPLKP 541 LKP Sbjct: 701 PQLKP 705 Score = 70.5 bits (171), Expect = 4e-12 Identities = 68/238 (28%), Positives = 108/238 (45%), Gaps = 20/238 (8%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 N+L+DE G++K++DFGLS KE + ++ CGT Y+APE++N++G+ AD WS Sbjct: 192 NILLDEEGHIKLTDFGLS--KEAIDHEKKAYSFCGTVEYMAPEVVNRQGHT-HSADWWSY 248 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRI--- 367 GV++ + E I K + PQ+ S++A+ LL L NP R+ Sbjct: 249 GVLM-----------GKDRKETMTLILKAKLGMPQFLSTEAQSLLRALFKRNPANRLGSG 297 Query: 368 --TMDKLIEHPWF-------------KKGYKPAVMLGTPRASKDLNDVQAAFSTDHKDGE 502 +++ H ++ K +KPAV A D T + D E Sbjct: 298 PDGAEEIKRHIFYSTIDWNKLYRREIKPPFKPAV------AQPD--------DTFYFDTE 343 Query: 503 GSRAEQPNSPLKPASLNAFDIISLSKGFDL--SGLFEKDQEQKSNSRFMTQKPASAIV 670 + +SP P S A L +GF +GL E D + ++ TQ P ++V Sbjct: 344 FTSRTPRDSPGIPPSAGAH---QLFRGFSFVATGLMEDDGKPRT-----TQAPLHSVV 393
>DCAK1_HUMAN (O15075) Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 1) Length = 740 Score = 93.2 bits (230), Expect = 6e-19 Identities = 57/137 (41%), Positives = 83/137 (60%), Gaps = 10/137 (7%) Frame = +2 Query: 17 NLLVDEHGN----LKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKAD 184 NLLV EH + LK+ DFGL+ + DG L+T CGTP YVAPEII + GY G K D Sbjct: 516 NLLVYEHQDGSKSLKLGDFGLATIV-----DGPLYTVCGTPTYVAPEIIAETGY-GLKVD 569 Query: 185 IWSCGVILFVLLAGYLPFQDS--NLMEMYRKISKGDVRYPQ--W--FSSDARKLLCRLLD 346 IW+ GVI ++LL G+ PF+ S + ++ +I G V +P W S A++L+ +L Sbjct: 570 IWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLL 629 Query: 347 PNPNTRITMDKLIEHPW 397 + + R + +++EHPW Sbjct: 630 VDVDQRFSAVQVLEHPW 646
>KAPC_DROME (P12370) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) (PKA C) Length = 352 Score = 92.8 bits (229), Expect = 8e-19 Identities = 52/133 (39%), Positives = 75/133 (56%), Gaps = 5/133 (3%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D G LKV+DFG + ++ G T CGTP Y+APEII KGY+ + D W+ Sbjct: 173 NLLIDSQGYLKVTDFGFA-----KRVKGRTWTLCGTPEYLAPEIILSKGYN-KAVDWWAL 226 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPN-----PNT 361 GV+++ + AGY PF +++Y KI G VR+P F SD + LL LL + N Sbjct: 227 GVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSDLKDLLRNLLQVDLTKRYGNL 286 Query: 362 RITMDKLIEHPWF 400 + ++ + WF Sbjct: 287 KAGVNDIKNQKWF 299
>KC61_SCHPO (Q9UU87) Probable serine/threonine-protein kinase C1919.01 (EC| 2.7.11.1) Length = 354 Score = 92.8 bits (229), Expect = 8e-19 Identities = 51/129 (39%), Positives = 75/129 (58%), Gaps = 2/129 (1%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINK--KGYDGEKADIW 190 N+L E+ NL V DFGL+ E +DG + GTPA++APE+ + K G+ DIW Sbjct: 205 NILFKENNNLCVIDFGLA---EFLPKDGFVKPASGTPAFMAPELFDNELKKIKGKPLDIW 261 Query: 191 SCGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRIT 370 S GV L+V+ PF S +++M I + P + +SD RKLL R L+ NP RIT Sbjct: 262 SMGVTLYVIAFAEFPFNGSTILDMINVIKGKSLMIPAYCNSDLRKLLERCLEKNPEKRIT 321 Query: 371 MDKLIEHPW 397 +++L+ P+ Sbjct: 322 IEELLRDPF 330
>KS6A1_HUMAN (Q15418) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1) (S6K-alpha| 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 92.8 bits (229), Expect = 8e-19 Identities = 62/185 (33%), Positives = 100/185 (54%), Gaps = 11/185 (5%) Frame = +2 Query: 20 LLVDEHGN---LKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIW 190 L VDE GN L++ DFG + K+ + ++GLL T C T +VAPE++ ++GYD E DIW Sbjct: 542 LYVDESGNPECLRICDFGFA--KQLRAENGLLMTPCYTANFVAPEVLKRQGYD-EGCDIW 598 Query: 191 SCGVILFVLLAGYLPFQD---SNLMEMYRKISKGDVRYP--QW--FSSDARKLLCRLLDP 349 S G++L+ +LAGY PF + E+ +I G W S A+ L+ ++L Sbjct: 599 SLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTLSGGNWNTVSETAKDLVSKMLHV 658 Query: 350 NPNTRITMDKLIEHPWF-KKGYKPAVMLGTPRASKDLNDVQAAFSTDHKDGEGSRAEQPN 526 +P+ R+T ++++HPW +K P L + +DL V+ A + + + +P Sbjct: 659 DPHQRLTAKQVLQHPWVTQKDKLPQSQL----SHQDLQLVKGAMAATY---SALNSSKPT 711 Query: 527 SPLKP 541 LKP Sbjct: 712 PQLKP 716 Score = 92.4 bits (228), Expect = 1e-18 Identities = 48/117 (41%), Positives = 73/117 (62%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 N+L+DE G++K++DFGLS KE + ++ CGT Y+APE++N++G+ AD WS Sbjct: 192 NILLDEEGHIKLTDFGLS--KEAIDHEKKAYSFCGTVEYMAPEVVNRQGHS-HSADWWSY 248 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRI 367 GV++F +L G LPFQ + E I K + PQ+ S++A+ LL L NP R+ Sbjct: 249 GVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSTEAQSLLRALFKRNPANRL 305
>PLK2_CAEEL (Q9N2L7) Serine/threonine-protein kinase plk-2 (EC 2.7.11.21)| (Polo-like kinase 2) Length = 632 Score = 92.8 bits (229), Expect = 8e-19 Identities = 50/135 (37%), Positives = 77/135 (57%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NL +++ +K+ DFGL+ + D T CGTP Y+APE++NK G+ E D+W+ Sbjct: 164 NLFLNDELQVKIGDFGLATTCD---NDERKKTLCGTPNYIAPEVLNKIGHSFE-VDLWAI 219 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 G IL++LL G+ PF+ +L E Y +I + P S+ A +L+ LLDP P+ R Sbjct: 220 GCILYILLFGHPPFESKSLEETYSRIKNNNYVIPTSASAAASQLIRVLLDPVPSRRPNAR 279 Query: 377 KLIEHPWFKKGYKPA 421 + +FK G+ PA Sbjct: 280 AVCRDHFFKSGFMPA 294
>TSSK2_HUMAN (Q96PF2) Testis-specific serine/threonine-protein kinase 2 (EC| 2.7.11.1) (TSSK-2) (Testis-specific kinase 2) (TSK-2) (Serine/threonine-protein kinase 22B) (DiGeorge syndrome protein G) Length = 358 Score = 92.8 bits (229), Expect = 8e-19 Identities = 47/135 (34%), Positives = 81/135 (60%), Gaps = 6/135 (4%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDG----LLHTTCGTPAYVAPEIINKKGYDGEKAD 184 NLL+D+ N+K+SDFG S K C + L T CG+ AY APE++ Y + D Sbjct: 141 NLLLDKDFNIKLSDFGFS--KRCLRDSNGRIILSKTFCGSAAYAAPEVLQSIPYQPKVYD 198 Query: 185 IWSCGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQW--FSSDARKLLCRLLDPNPN 358 IWS GVIL++++ G +P+ DS++ +M R + V +P+ + + + L+ R+L P+ + Sbjct: 199 IWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKNLTCECKDLIYRMLQPDVS 258 Query: 359 TRITMDKLIEHPWFK 403 R+ +D+++ H W + Sbjct: 259 QRLHIDEILSHSWLQ 273
>SAPK8_ORYSA (Q7Y0B9) Serine/threonine-protein kinase SAPK8 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 8) Length = 371 Score = 92.4 bits (228), Expect = 1e-18 Identities = 61/171 (35%), Positives = 91/171 (53%), Gaps = 6/171 (3%) Frame = +2 Query: 44 LKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSCGVILFVLLA 223 LK+ DFG S Q +T GTPAY+APE++ KK YDG+ AD+WSCGV L+V++ Sbjct: 168 LKICDFGYSKSSVLHSQP---KSTVGTPAYIAPEVLLKKEYDGKTADVWSCGVTLYVMVV 224 Query: 224 GYLPFQDSNLMEMYRKISKG--DVRY--PQ--WFSSDARKLLCRLLDPNPNTRITMDKLI 385 G PF+D + +RK + +V+Y P+ S + R L+ R+ +P+ RIT+ ++ Sbjct: 225 GAYPFEDPEEPKNFRKTIQRILNVQYSIPENVDISPECRHLISRIFVGDPSLRITIPEIR 284 Query: 386 EHPWFKKGYKPAVMLGTPRASKDLNDVQAAFSTDHKDGEGSRAEQPNSPLK 538 H WF K PA DL D D S+ E+P+ P++ Sbjct: 285 SHGWFLKNL-PA----------DLMD---------DDSMSSQYEEPDQPMQ 315
>TRIB1_HUMAN (Q96RU8) Tribbles homolog 1 (TRB-1) (SKIP1) (G-protein-coupled| receptor induced protein 2) (GIG-2) Length = 372 Score = 92.4 bits (228), Expect = 1e-18 Identities = 46/110 (41%), Positives = 66/110 (60%), Gaps = 1/110 (0%) Frame = +2 Query: 92 QDGLLHTTCGTPAYVAPEIINKKG-YDGEKADIWSCGVILFVLLAGYLPFQDSNLMEMYR 268 +D L G PAYV+PEI+N G Y G+ AD+WS GV+L+ LL G PF DS+ ++ Sbjct: 235 EDDALSDKHGCPAYVSPEILNTTGTYSGKAADVWSLGVMLYTLLVGRYPFHDSDPSALFS 294 Query: 269 KISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMDKLIEHPWFKKGYKP 418 KI +G P+ S AR L+ LL P+ R+T +++ HPWF+ +P Sbjct: 295 KIRRGQFCIPEHISPKARCLIRSLLRREPSERLTAPEILLHPWFESVLEP 344
>STK33_HUMAN (Q9BYT3) Serine/threonine-protein kinase 33 (EC 2.7.11.1)| Length = 514 Score = 92.0 bits (227), Expect = 1e-18 Identities = 64/222 (28%), Positives = 119/222 (53%), Gaps = 8/222 (3%) Frame = +2 Query: 23 LVDEHG----NLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIW 190 L+D++ N+KV+DFGL A+K+ + + +L TCGTP Y+APE+I+ Y ++ DIW Sbjct: 250 LIDDNNEINLNIKVTDFGL-AVKKQSRSEAMLQATCGTPIYMAPEVISAHDYS-QQCDIW 307 Query: 191 SCGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQ--W--FSSDARKLLCRLLDPNPN 358 S GV++++LL G PF S+ +++ I KG++ + W S A+ +L +L+ +P Sbjct: 308 SIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQLMKVDPA 367 Query: 359 TRITMDKLIEHPWFKKGYKPAVMLGTPRASKDLNDVQAAFSTDHKDGEGSRAEQPNSPLK 538 RIT +L+++ W G K L + R + L ++ + + + E + E+ N P Sbjct: 368 HRITAKELLDNQWL-TGNK----LSSVRPTNVL-EMMKEWKNNPESVEENTTEEKNKPST 421 Query: 539 PASLNAFDIISLSKGFDLSGLFEKDQEQKSNSRFMTQKPASA 664 L ++ + ++E+K ++ + Q PA++ Sbjct: 422 EEKLKSYQPWG---NVPDANYTSDEEEEKQSTAYEKQFPATS 460
>MYLK_DICDI (P25323) Myosin light chain kinase (EC 2.7.11.18) (MLCK)| Length = 295 Score = 92.0 bits (227), Expect = 1e-18 Identities = 49/136 (36%), Positives = 80/136 (58%), Gaps = 7/136 (5%) Frame = +2 Query: 17 NLLV---DEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADI 187 NLL+ + H + ++DFGLS + Q ++ T CGTP+YVAPE++N GYD E D+ Sbjct: 135 NLLLKSKENHLEVAIADFGLSKIIG---QTLVMQTACGTPSYVAPEVLNATGYDKE-VDM 190 Query: 188 WSCGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQ--W--FSSDARKLLCRLLDPNP 355 WS GVI ++LL G+ PF + E++ +I + + +P+ W S +A+ + +LL + Sbjct: 191 WSIGVITYILLCGFPPFYGDTVPEIFEQIMEANYEFPEEYWGGISKEAKDFIGKLLVVDV 250 Query: 356 NTRITMDKLIEHPWFK 403 + R+ + HPW K Sbjct: 251 SKRLNATNALNHPWLK 266
>KCC2A_RAT (P11275) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 92.0 bits (227), Expect = 1e-18 Identities = 47/122 (38%), Positives = 77/122 (63%), Gaps = 4/122 (3%) Frame = +2 Query: 44 LKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSCGVILFVLLA 223 +K++DFGL+ E ++Q GTP Y++PE++ K Y G+ D+W+CGVIL++LL Sbjct: 152 VKLADFGLAIEVEGEQQAWF--GFAGTPGYLSPEVLRKDPY-GKPVDLWACGVILYILLV 208 Query: 224 GYLPFQDSNLMEMYRKISKG--DVRYPQW--FSSDARKLLCRLLDPNPNTRITMDKLIEH 391 GY PF D + +Y++I G D P+W + +A+ L+ ++L NP+ RIT + ++H Sbjct: 209 GYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKH 268 Query: 392 PW 397 PW Sbjct: 269 PW 270
>KCC2A_PONPY (Q5RCC4) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 92.0 bits (227), Expect = 1e-18 Identities = 47/122 (38%), Positives = 77/122 (63%), Gaps = 4/122 (3%) Frame = +2 Query: 44 LKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSCGVILFVLLA 223 +K++DFGL+ E ++Q GTP Y++PE++ K Y G+ D+W+CGVIL++LL Sbjct: 152 VKLADFGLAIEVEGEQQAWF--GFAGTPGYLSPEVLRKDPY-GKPVDLWACGVILYILLV 208 Query: 224 GYLPFQDSNLMEMYRKISKG--DVRYPQW--FSSDARKLLCRLLDPNPNTRITMDKLIEH 391 GY PF D + +Y++I G D P+W + +A+ L+ ++L NP+ RIT + ++H Sbjct: 209 GYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKH 268 Query: 392 PW 397 PW Sbjct: 269 PW 270
>KCC2A_HUMAN (Q9UQM7) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 92.0 bits (227), Expect = 1e-18 Identities = 47/122 (38%), Positives = 77/122 (63%), Gaps = 4/122 (3%) Frame = +2 Query: 44 LKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSCGVILFVLLA 223 +K++DFGL+ E ++Q GTP Y++PE++ K Y G+ D+W+CGVIL++LL Sbjct: 152 VKLADFGLAIEVEGEQQAWF--GFAGTPGYLSPEVLRKDPY-GKPVDLWACGVILYILLV 208 Query: 224 GYLPFQDSNLMEMYRKISKG--DVRYPQW--FSSDARKLLCRLLDPNPNTRITMDKLIEH 391 GY PF D + +Y++I G D P+W + +A+ L+ ++L NP+ RIT + ++H Sbjct: 209 GYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKH 268 Query: 392 PW 397 PW Sbjct: 269 PW 270
>KS6AB_XENLA (P10666) Ribosomal protein S6 kinase 2 beta (EC 2.7.11.1)| (Ribosomal protein S6 kinase II beta) (S6KII-beta) (P90-RSK) Length = 629 Score = 92.0 bits (227), Expect = 1e-18 Identities = 51/133 (38%), Positives = 79/133 (59%), Gaps = 5/133 (3%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 N+L+DE G++K++DFGLS KE + ++ CGT Y+APE++N++G+ AD WS Sbjct: 192 NILLDEEGHIKLTDFGLS--KEAIDHEKKAYSFCGTVEYMAPEVVNRQGHS-HGADWWSY 248 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRI--- 367 GV++F +L G LPFQ + E I K + PQ+ S++A+ LL L N R+ Sbjct: 249 GVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSNEAQSLLRALFKRNATNRLGSG 308 Query: 368 --TMDKLIEHPWF 400 ++L HP+F Sbjct: 309 VEGAEELKRHPFF 321 Score = 72.4 bits (176), Expect = 1e-12 Identities = 36/76 (47%), Positives = 53/76 (69%), Gaps = 3/76 (3%) Frame = +2 Query: 20 LLVDEHGN---LKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIW 190 L VDE G+ +++ DFG S K+ + ++GLL T C T +VAPE++ ++GYD E DIW Sbjct: 540 LYVDESGDPESIRICDFGFS--KQLRAENGLLMTPCYTANFVAPEVLKRQGYD-EGCDIW 596 Query: 191 SCGVILFVLLAGYLPF 238 S G++L+ +LAGY PF Sbjct: 597 SLGILLYTMLAGYTPF 612
>KPC1_CAEEL (P34722) Protein kinase C-like 1 (EC 2.7.11.13) (PKC)| (Tetradecanoyl phorbol acetate resistant protein 1) Length = 704 Score = 92.0 bits (227), Expect = 1e-18 Identities = 48/126 (38%), Positives = 75/126 (59%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 N+L+D G++K++DFG+ A E +++G+ T CGTP Y++PEII + Y+ E D WS Sbjct: 504 NVLLDCDGHIKLADFGM-AKTEMNRENGMASTFCGTPDYISPEIIKGQLYN-EAVDFWSF 561 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 GV+++ +L G PF E++ I +P+ S +A K L L D NPNTR+ M Sbjct: 562 GVLMYEMLVGQSPFHGEGEDELFDSILNERPYFPKTISKEAAKCLSALFDRNPNTRLGMP 621 Query: 377 KLIEHP 394 + + P Sbjct: 622 ECPDGP 627
>PLK1_CAEEL (P34331) Serine/threonine-protein kinase plk-1 (EC 2.7.11.21)| (Polo-like kinase 1) Length = 649 Score = 92.0 bits (227), Expect = 1e-18 Identities = 48/134 (35%), Positives = 75/134 (55%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NL +++ +K+ DFGL+ ++ T CGTP Y+APE++NK G+ E DIW+ Sbjct: 167 NLFLNDDLVVKIGDFGLATTVNGDERK---KTLCGTPNYIAPEVLNKAGHSFE-VDIWAV 222 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 G IL++LL G PF+ +L E Y +I + P + A L+ ++LDP P R T Sbjct: 223 GCILYILLFGQPPFESKSLEETYSRIRHNNYTIPSIATQPAASLIRKMLDPEPTRRPTAK 282 Query: 377 KLIEHPWFKKGYKP 418 ++ +FK G+ P Sbjct: 283 QVQRDGFFKSGFMP 296
>CHK1_YEAST (P38147) Serine/threonine-protein kinase CHK1 (EC 2.7.11.1)| (Checkpoint kinase 1) Length = 527 Score = 92.0 bits (227), Expect = 1e-18 Identities = 49/136 (36%), Positives = 88/136 (64%), Gaps = 9/136 (6%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTC---GTPAYVAPEII-NKKGYDGEKAD 184 N+L+D++GNLK++DFGL++ + +++DG L + G+P Y+APE++ +++GY ++ D Sbjct: 147 NILLDKNGNLKLADFGLAS--QFRRKDGTLRVSMDQRGSPPYMAPEVLYSEEGYYADRTD 204 Query: 185 IWSCGVILFVLLAGYLPFQDSNLME---MYRKISKGDVRYPQWFSSDAR--KLLCRLLDP 349 IWS G++LFVLL G P++ +L ++ + G++ + W + LL ++L P Sbjct: 205 IWSIGILLFVLLTGQTPWELPSLENEDFVFFIENDGNLNWGPWSKIEFTHLNLLRKILQP 264 Query: 350 NPNTRITMDKLIEHPW 397 +PN R+T+ L HPW Sbjct: 265 DPNKRVTLKALKLHPW 280
>YPK1_YEAST (P12688) Serine/threonine-protein kinase YPK1 (EC 2.7.11.1)| Length = 680 Score = 92.0 bits (227), Expect = 1e-18 Identities = 56/152 (36%), Positives = 83/152 (54%), Gaps = 16/152 (10%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 N+L+D G++ + DFGL L K D T CGTP Y+APE++ GY + D W+ Sbjct: 475 NILLDYQGHIALCDFGLCKLN--MKDDDKTDTFCGTPEYLAPELLLGLGYT-KAVDWWTL 531 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRI--- 367 GV+L+ +L G P+ D ++ +MY+KI + + +P F DA+ LL LL +P R+ Sbjct: 532 GVLLYEMLTGLPPYYDEDVPKMYKKILQEPLVFPDGFDRDAKDLLIGLLSRDPTRRLGYN 591 Query: 368 TMDKLIEHPWFK---------KG----YKPAV 424 D++ HP+F KG YKPAV Sbjct: 592 GADEIRNHPFFSQLSWKRLLMKGYIPPYKPAV 623
>YPK2_YEAST (P18961) Serine/threonine-protein kinase YPK2/YKR2 (EC 2.7.11.1)| Length = 677 Score = 91.7 bits (226), Expect = 2e-18 Identities = 52/146 (35%), Positives = 82/146 (56%), Gaps = 12/146 (8%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 N+L+D G++ + DFGL L K + T CGTP Y+APEI+ +GY + D W+ Sbjct: 472 NILLDYQGHIALCDFGLCKLN--MKDNDKTDTFCGTPEYLAPEILLGQGYT-KTVDWWTL 528 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITM- 373 G++L+ ++ G P+ D N+ MY+KI + + +P F A+ LL LL +P+ R+ + Sbjct: 529 GILLYEMMTGLPPYYDENVPVMYKKILQQPLLFPDGFDPAAKDLLIGLLSRDPSRRLGVN 588 Query: 374 --DKLIEHPWFK---------KGYKP 418 D++ HP+FK KGY P Sbjct: 589 GTDEIRNHPFFKDISWKKLLLKGYIP 614
>KCC2D_RAT (P15791) Calcium/calmodulin-dependent protein kinase type II delta| chain (EC 2.7.11.17) (CaM-kinase II delta chain) (CaM kinase II delta subunit) (CaMK-II delta subunit) Length = 533 Score = 91.3 bits (225), Expect = 2e-18 Identities = 47/122 (38%), Positives = 74/122 (60%), Gaps = 4/122 (3%) Frame = +2 Query: 44 LKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSCGVILFVLLA 223 +K++DFGL+ E Q GTP Y++PE++ K Y G+ D+W+CGVIL++LL Sbjct: 153 VKLADFGLAI--EVQGDQQAWFGFAGTPGYLSPEVLRKDPY-GKPVDMWACGVILYILLV 209 Query: 224 GYLPFQDSNLMEMYRKISKG--DVRYPQW--FSSDARKLLCRLLDPNPNTRITMDKLIEH 391 GY PF D + +Y++I G D P+W + +A+ L+ ++L NP RIT + ++H Sbjct: 210 GYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKH 269 Query: 392 PW 397 PW Sbjct: 270 PW 271
>KCC2D_HUMAN (Q13557) Calcium/calmodulin-dependent protein kinase type II delta| chain (EC 2.7.11.17) (CaM-kinase II delta chain) (CaM kinase II delta subunit) (CaMK-II delta subunit) Length = 499 Score = 91.3 bits (225), Expect = 2e-18 Identities = 47/122 (38%), Positives = 74/122 (60%), Gaps = 4/122 (3%) Frame = +2 Query: 44 LKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSCGVILFVLLA 223 +K++DFGL+ E Q GTP Y++PE++ K Y G+ D+W+CGVIL++LL Sbjct: 153 VKLADFGLAI--EVQGDQQAWFGFAGTPGYLSPEVLRKDPY-GKPVDMWACGVILYILLV 209 Query: 224 GYLPFQDSNLMEMYRKISKG--DVRYPQW--FSSDARKLLCRLLDPNPNTRITMDKLIEH 391 GY PF D + +Y++I G D P+W + +A+ L+ ++L NP RIT + ++H Sbjct: 210 GYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKH 269 Query: 392 PW 397 PW Sbjct: 270 PW 271
>TRIB1_MOUSE (Q8K4K4) Tribbles homolog 1 (TRB-1)| Length = 372 Score = 91.3 bits (225), Expect = 2e-18 Identities = 46/110 (41%), Positives = 66/110 (60%), Gaps = 1/110 (0%) Frame = +2 Query: 92 QDGLLHTTCGTPAYVAPEIINKKG-YDGEKADIWSCGVILFVLLAGYLPFQDSNLMEMYR 268 +D L G PAYV+PEI+N G Y G+ AD+WS GV+L+ LL G PF DS+ ++ Sbjct: 235 EDDALSDKHGCPAYVSPEILNTTGTYSGKAADVWSLGVMLYTLLVGRYPFHDSDPSALFS 294 Query: 269 KISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMDKLIEHPWFKKGYKP 418 KI +G P+ S AR L+ LL P+ R+T +++ HPWF+ +P Sbjct: 295 KIRRGQFCIPEHVSPKARCLIRSLLRREPSERLTAPQILLHPWFEYVLEP 344
>AKT3_MOUSE (Q9WUA6) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) Length = 479 Score = 90.9 bits (224), Expect = 3e-18 Identities = 44/117 (37%), Positives = 72/117 (61%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NL++D+ G++K++DFGL KE + T CGTP Y+APE++ Y G D W Sbjct: 276 NLMLDKDGHIKITDFGLC--KEGITDAATMKTFCGTPEYLAPEVLEDNDY-GRAVDWWGL 332 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRI 367 GV+++ ++ G LPF + + +++ I D+++P+ SSDA+ LL LL +PN R+ Sbjct: 333 GVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKDPNKRL 389
>AKT3_HUMAN (Q9Y243) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) (STK-2) Length = 479 Score = 90.9 bits (224), Expect = 3e-18 Identities = 44/117 (37%), Positives = 72/117 (61%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NL++D+ G++K++DFGL KE + T CGTP Y+APE++ Y G D W Sbjct: 276 NLMLDKDGHIKITDFGLC--KEGITDAATMKTFCGTPEYLAPEVLEDNDY-GRAVDWWGL 332 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRI 367 GV+++ ++ G LPF + + +++ I D+++P+ SSDA+ LL LL +PN R+ Sbjct: 333 GVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKDPNKRL 389
>KAPCG_HUMAN (P22612) cAMP-dependent protein kinase, gamma-catalytic subunit (EC| 2.7.11.11) (PKA C-gamma) Length = 350 Score = 90.9 bits (224), Expect = 3e-18 Identities = 51/133 (38%), Positives = 75/133 (56%), Gaps = 5/133 (3%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D+ G L+V+DFG + ++ G T CGTP Y+APEII KGY+ + D W+ Sbjct: 171 NLLIDQQGYLQVTDFGFA-----KRVKGRTWTLCGTPEYLAPEIILSKGYN-KAVDWWAL 224 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPN-----PNT 361 GV+++ + G+ PF +++Y KI G VR+P SSD + LL LL + N Sbjct: 225 GVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNL 284 Query: 362 RITMDKLIEHPWF 400 R + + H WF Sbjct: 285 RNGVGDIKNHKWF 297
>CDPK2_PLAF7 (Q8ICR0) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (PfCDPK2)| Length = 508 Score = 90.9 bits (224), Expect = 3e-18 Identities = 54/123 (43%), Positives = 75/123 (60%), Gaps = 5/123 (4%) Frame = +2 Query: 44 LKVSDFGLSALKECQKQDGLLHTT-CGTPAYVAPEIINKKGYDGEKADIWSCGVILFVLL 220 LK+ DFGLS G TT GTP YVAP++++ K YD +K DIWS GVI++ LL Sbjct: 208 LKIIDFGLSK----NLGTGEFTTTKAGTPYYVAPQVLDGK-YD-KKCDIWSSGVIMYTLL 261 Query: 221 AGYLPFQDSNLMEMYRKISKGDVRYPQ--W--FSSDARKLLCRLLDPNPNTRITMDKLIE 388 GY PF E+ +K+ KG+ + + W SSDA+ L+ +LL NPN R T+++ + Sbjct: 262 CGYPPFYGDTDNEVLKKVKKGEFCFYENDWGSISSDAKNLITKLLTYNPNERCTIEEALN 321 Query: 389 HPW 397 HPW Sbjct: 322 HPW 324
>KAPC_CAEEL (P21137) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) (PKA C) Length = 404 Score = 90.9 bits (224), Expect = 3e-18 Identities = 50/133 (37%), Positives = 76/133 (57%), Gaps = 5/133 (3%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+D G LK++DFG + ++ G T CGTP Y+APEII KGY+ + D W+ Sbjct: 209 NLLIDSTGYLKITDFGFA-----KRVKGRTWTLCGTPEYLAPEIILSKGYN-KAVDWWAL 262 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPN-----PNT 361 GV+++ + AGY PF +++Y KI G V++P FS++ + LL LL + N Sbjct: 263 GVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVDLTKRYGNL 322 Query: 362 RITMDKLIEHPWF 400 + + + H WF Sbjct: 323 KNGVADIKNHKWF 335
>AKT3_RAT (Q63484) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) Length = 454 Score = 90.9 bits (224), Expect = 3e-18 Identities = 44/117 (37%), Positives = 72/117 (61%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NL++D+ G++K++DFGL KE + T CGTP Y+APE++ Y G D W Sbjct: 276 NLMLDKDGHIKITDFGLC--KEGITDAATMKTFCGTPEYLAPEVLEDNDY-GRAVDWWGL 332 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRI 367 GV+++ ++ G LPF + + +++ I D+++P+ SSDA+ LL LL +PN R+ Sbjct: 333 GVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKDPNKRL 389
>CDPK2_PLAFK (O15865) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (PfCDPK2)| Length = 512 Score = 90.9 bits (224), Expect = 3e-18 Identities = 54/123 (43%), Positives = 75/123 (60%), Gaps = 5/123 (4%) Frame = +2 Query: 44 LKVSDFGLSALKECQKQDGLLHTT-CGTPAYVAPEIINKKGYDGEKADIWSCGVILFVLL 220 LK+ DFGLS G TT GTP YVAP++++ K YD +K DIWS GVI++ LL Sbjct: 208 LKIIDFGLSK----NLGTGEFTTTKAGTPYYVAPQVLDGK-YD-KKCDIWSSGVIMYTLL 261 Query: 221 AGYLPFQDSNLMEMYRKISKGDVRYPQ--W--FSSDARKLLCRLLDPNPNTRITMDKLIE 388 GY PF E+ +K+ KG+ + + W SSDA+ L+ +LL NPN R T+++ + Sbjct: 262 CGYPPFYGDTDNEVLKKVKKGEFCFYENDWGSISSDAKNLITKLLTYNPNERCTIEEALN 321 Query: 389 HPW 397 HPW Sbjct: 322 HPW 324
>AURKC_MOUSE (O88445) Serine/threonine-protein kinase 13 (EC 2.7.11.1)| (Aurora/Ipl1/Eg2 protein 1) (Aurora-C) Length = 282 Score = 90.5 bits (223), Expect = 4e-18 Identities = 46/130 (35%), Positives = 79/130 (60%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+ +G +K+SDFG S ++ T CGT Y+ PE+I +K Y+ E D+W Sbjct: 144 NLLLGLNGEVKISDFGWSVHTPSLRRK----TMCGTLDYLPPEMIAQKPYN-EMVDLWCI 198 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 GV+ + LL G PF+ S E YR+I + D ++P + A+ L+ +LL +P+ R+++ Sbjct: 199 GVLCYELLVGKPPFESSTSSETYRRIRQVDFKFPSSVPAGAQDLISKLLRYHPSERLSLA 258 Query: 377 KLIEHPWFKK 406 ++++HPW ++ Sbjct: 259 QVLKHPWVRE 268
>KPC2_APLCA (Q16975) Calcium-independent protein kinase C (EC 2.7.11.13) (APL| II) Length = 743 Score = 90.5 bits (223), Expect = 4e-18 Identities = 47/135 (34%), Positives = 75/135 (55%), Gaps = 7/135 (5%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 N+L+D G+ K++DFG+ KE ++ L T CGTP Y+APEI+ + YD D W+ Sbjct: 532 NILLDAEGHCKIADFGMC--KEGMTENKLTQTFCGTPDYIAPEILQELKYDAS-VDWWAL 588 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRI--- 367 GV+++ ++AG PF+ N +++ I DV YP W S +A +L + NP R+ Sbjct: 589 GVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKGFMTKNPAKRLGCV 648 Query: 368 ----TMDKLIEHPWF 400 ++ HP+F Sbjct: 649 TTQGCEKAILVHPFF 663
>KPCE_MOUSE (P16054) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 737 Score = 90.1 bits (222), Expect = 5e-18 Identities = 49/140 (35%), Positives = 81/140 (57%), Gaps = 10/140 (7%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQK--QDGLLHTT-CGTPAYVAPEIINKKGYDGEKADI 187 N+L+D G+ K++DFG+ C++ +G+ TT CGTP Y+APEI+ + Y G D Sbjct: 537 NILLDAEGHCKLADFGM-----CKEGIMNGVTTTTFCGTPDYIAPEILQELEY-GPSVDW 590 Query: 188 WSCGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRI 367 W+ GV+++ ++AG PF+ N +++ I DV YP W S +A +L + NP+ R+ Sbjct: 591 WALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFMTKNPHKRL 650 Query: 368 TM-------DKLIEHPWFKK 406 D + +HP+FK+ Sbjct: 651 GCVAAQNGEDAIKQHPFFKE 670
>KPCL_MOUSE (P23298) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 683 Score = 90.1 bits (222), Expect = 5e-18 Identities = 48/137 (35%), Positives = 77/137 (56%), Gaps = 7/137 (5%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTT-CGTPAYVAPEIINKKGYDGEKADIWS 193 N+L+D G+ K++DFG+ C +G+ T CGTP Y+APEI+ + Y G D W+ Sbjct: 484 NVLLDHEGHCKLADFGMCKEGIC---NGVTTATFCGTPDYIAPEILQEMLY-GPAVDWWA 539 Query: 194 CGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITM 373 GV+L+ +L G+ PF+ N +++ I +V YP W DAR +L + NP R+ Sbjct: 540 MGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHEDARGILKSFMTKNPTMRLGS 599 Query: 374 ------DKLIEHPWFKK 406 +++ HP+FK+ Sbjct: 600 LTQGGEHEILRHPFFKE 616
>KCC1B_RAT (O70150) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase homolog) Length = 343 Score = 90.1 bits (222), Expect = 5e-18 Identities = 47/126 (37%), Positives = 72/126 (57%), Gaps = 4/126 (3%) Frame = +2 Query: 32 EHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSCGVILF 211 E + VSDFGLS ++ +L T CGTP YVAPE++ +K Y G+ D+W+ GVI + Sbjct: 149 EDSKIMVSDFGLSKIQA----GNMLGTACGTPGYVAPELLEQKPY-GKAVDVWALGVISY 203 Query: 212 VLLAGYLPFQDSNLMEMYRKISKGDVRY--PQW--FSSDARKLLCRLLDPNPNTRITMDK 379 +LL GY PF D + E++ +I + + P W S A+ + LL+ +P R T + Sbjct: 204 ILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDFIRHLLERDPQKRFTCQQ 263 Query: 380 LIEHPW 397 ++H W Sbjct: 264 ALQHLW 269
>KCC1B_MOUSE (Q9QYK9) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase homolog) Length = 343 Score = 90.1 bits (222), Expect = 5e-18 Identities = 47/126 (37%), Positives = 72/126 (57%), Gaps = 4/126 (3%) Frame = +2 Query: 32 EHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSCGVILF 211 E + VSDFGLS ++ +L T CGTP YVAPE++ +K Y G+ D+W+ GVI + Sbjct: 149 EDSKIMVSDFGLSKIQA----GNMLGTACGTPGYVAPELLEQKPY-GKAVDVWALGVISY 203 Query: 212 VLLAGYLPFQDSNLMEMYRKISKGDVRY--PQW--FSSDARKLLCRLLDPNPNTRITMDK 379 +LL GY PF D + E++ +I + + P W S A+ + LL+ +P R T + Sbjct: 204 ILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDFIRHLLERDPQKRFTCQQ 263 Query: 380 LIEHPW 397 ++H W Sbjct: 264 ALQHLW 269
>IPL1_ASHGO (Q755C4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 367 Score = 90.1 bits (222), Expect = 5e-18 Identities = 43/130 (33%), Positives = 79/130 (60%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 N+++ + +K++DFG S + + T CGT Y++PE+I + Y+ EK D+W+ Sbjct: 237 NIIIGFNNTIKLTDFGWSVITP---KGSKRKTLCGTVDYLSPELIRSREYN-EKVDVWAL 292 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 GV+ + LL G PF++ + Y++I K ++ +P ++AR L+ RLL+ +P RI + Sbjct: 293 GVLTYELLVGSPPFEEESKELTYKRILKRNLIFPDHVDTEARHLISRLLEYDPGDRIPLK 352 Query: 377 KLIEHPWFKK 406 ++ +HPW +K Sbjct: 353 EVKKHPWIEK 362
>KPCE_HUMAN (Q02156) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 737 Score = 89.7 bits (221), Expect = 7e-18 Identities = 48/142 (33%), Positives = 80/142 (56%), Gaps = 12/142 (8%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLH-----TTCGTPAYVAPEIINKKGYDGEKA 181 N+L+D G+ K++DFG+ ++G+L+ T CGTP Y+APEI+ + Y G Sbjct: 537 NILLDAEGHCKLADFGMC-------KEGILNGVTTTTFCGTPDYIAPEILQELEY-GPSV 588 Query: 182 DIWSCGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNT 361 D W+ GV+++ ++AG PF+ N +++ I DV YP W S +A +L + NP+ Sbjct: 589 DWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFMTKNPHK 648 Query: 362 RITM-------DKLIEHPWFKK 406 R+ D + +HP+FK+ Sbjct: 649 RLGCVASQNGEDAIKQHPFFKE 670
>KPC1B_CAEEL (P34885) Protein kinase C-like 1B (EC 2.7.11.13) (PKC1B)| Length = 707 Score = 89.7 bits (221), Expect = 7e-18 Identities = 47/137 (34%), Positives = 76/137 (55%), Gaps = 7/137 (5%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 N+L+D G+ +++DFG+ KE +D L T CGTP Y+APEI+ + Y G D W+ Sbjct: 507 NILLDAEGHCRLADFGMC--KEGINKDNLTSTFCGTPDYIAPEILQEMEY-GVSVDWWAL 563 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITM- 373 GV+++ ++AG PF+ N +++ I DV YP W S +A +L + N R+ Sbjct: 564 GVLMYEMMAGQPPFEADNEDDLFEAILNDDVLYPVWLSKEAVNILKAFMTKNAGKRLGCV 623 Query: 374 ------DKLIEHPWFKK 406 D + HP+F++ Sbjct: 624 VSQGGEDAIRAHPFFRE 640
>KPCE_RABIT (P10830) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 736 Score = 89.7 bits (221), Expect = 7e-18 Identities = 48/142 (33%), Positives = 80/142 (56%), Gaps = 12/142 (8%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLH-----TTCGTPAYVAPEIINKKGYDGEKA 181 N+L+D G+ K++DFG+ ++G+L+ T CGTP Y+APEI+ + Y G Sbjct: 536 NILLDAEGHCKLADFGMC-------KEGILNGVTTTTFCGTPDYIAPEILQELEY-GPSV 587 Query: 182 DIWSCGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNT 361 D W+ GV+++ ++AG PF+ N +++ I DV YP W S +A +L + NP+ Sbjct: 588 DWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFMTKNPHK 647 Query: 362 RITM-------DKLIEHPWFKK 406 R+ D + +HP+FK+ Sbjct: 648 RLGCVAAQNGEDAIKQHPFFKE 669
>PLK4_HUMAN (O00444) Serine/threonine-protein kinase PLK4 (EC 2.7.11.21)| (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine-protein kinase 18) Length = 970 Score = 89.7 bits (221), Expect = 7e-18 Identities = 47/158 (29%), Positives = 84/158 (53%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+ + N+K++DFGL+ + + +T CGTP Y++PEI + + G ++D+WS Sbjct: 141 NLLLTRNMNIKIADFGLATQLKMPHEKH--YTLCGTPNYISPEIATRSAH-GLESDVWSL 197 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 G + + LL G PF + K+ D P + S +A+ L+ +LL NP R+++ Sbjct: 198 GCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPTFLSIEAKDLIHQLLRRNPADRLSLS 257 Query: 377 KLIEHPWFKKGYKPAVMLGTPRASKDLNDVQAAFSTDH 490 +++HP+ + + SKDL V+ + + H Sbjct: 258 SVLDHPFMSR--------NSSTKSKDLGTVEDSIDSGH 287
>PLK4_MOUSE (Q64702) Serine/threonine-protein kinase PLK4 (EC 2.7.11.21)| (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine-protein kinase 18) Length = 925 Score = 89.7 bits (221), Expect = 7e-18 Identities = 47/158 (29%), Positives = 83/158 (52%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 N+L+ + N+K++DFGL+ + +T CGTP Y++PEI + + G ++DIWS Sbjct: 141 NILLTRNMNIKIADFGLATQLNMPHEKH--YTLCGTPNYISPEIATRSAH-GLESDIWSL 197 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 G + + LL G PF + K+ D P + S +A+ L+ +LL NP R+++ Sbjct: 198 GCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPAFLSREAQDLIHQLLRRNPADRLSLS 257 Query: 377 KLIEHPWFKKGYKPAVMLGTPRASKDLNDVQAAFSTDH 490 +++HP+ + P SKD+ V+ + + H Sbjct: 258 SVLDHPFMSRNPSP--------KSKDVGTVEDSMDSGH 287
>CDPK1_PLAFK (P62343) Calcium-dependent protein kinase 1 (EC 2.7.11.1) (PfCPK)| (PfCDPK1) Length = 523 Score = 89.7 bits (221), Expect = 7e-18 Identities = 52/135 (38%), Positives = 77/135 (57%), Gaps = 6/135 (4%) Frame = +2 Query: 20 LLVDEHG--NLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWS 193 LL ++H N+K+ DFGLS+ +D L GT Y+APE++ KK EK D+WS Sbjct: 197 LLENKHSLLNIKIVDFGLSSFFS---KDNKLRDRLGTAYYIAPEVLRKKY--NEKCDVWS 251 Query: 194 CGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYP--QW--FSSDARKLLCRLLDPNPNT 361 CGVIL++LL GY PF N ++ +K+ KG + W S +A++L+ +L + N Sbjct: 252 CGVILYILLCGYPPFGGQNDQDIIKKVEKGKYYFDFNDWKNISEEAKELIKLMLTYDYNK 311 Query: 362 RITMDKLIEHPWFKK 406 RIT + + W KK Sbjct: 312 RITAKEALNSKWIKK 326
>CDPK1_PLAF7 (P62344) Calcium-dependent protein kinase 1 (EC 2.7.11.1)| Length = 523 Score = 89.7 bits (221), Expect = 7e-18 Identities = 52/135 (38%), Positives = 77/135 (57%), Gaps = 6/135 (4%) Frame = +2 Query: 20 LLVDEHG--NLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWS 193 LL ++H N+K+ DFGLS+ +D L GT Y+APE++ KK EK D+WS Sbjct: 197 LLENKHSLLNIKIVDFGLSSFFS---KDNKLRDRLGTAYYIAPEVLRKKY--NEKCDVWS 251 Query: 194 CGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYP--QW--FSSDARKLLCRLLDPNPNT 361 CGVIL++LL GY PF N ++ +K+ KG + W S +A++L+ +L + N Sbjct: 252 CGVILYILLCGYPPFGGQNDQDIIKKVEKGKYYFDFNDWKNISEEAKELIKLMLTYDYNK 311 Query: 362 RITMDKLIEHPWFKK 406 RIT + + W KK Sbjct: 312 RITAKEALNSKWIKK 326
>IPL1_DEBHA (Q6BVA0) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 412 Score = 89.7 bits (221), Expect = 7e-18 Identities = 46/127 (36%), Positives = 73/127 (57%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 N+L+ +K+SDFG S +K T CGT Y+ PE+I +D DIWS Sbjct: 276 NILLSTDNCIKLSDFGWS-VKSLPSSSTKRLTICGTLDYLPPEMIESNEHD-YTVDIWSL 333 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 G++ + L G PF++ + Y++I+K D++ P + SS+A L+ RLL +P RIT+ Sbjct: 334 GILCYEFLVGKPPFEEIDKNSTYKRIAKVDLKIPSFLSSEATDLILRLLQKSPKKRITLA 393 Query: 377 KLIEHPW 397 +++ HPW Sbjct: 394 EVMNHPW 400
>KS6A5_HUMAN (O75582) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RSKL) Length = 802 Score = 89.4 bits (220), Expect = 9e-18 Identities = 56/143 (39%), Positives = 80/143 (55%), Gaps = 13/143 (9%) Frame = +2 Query: 20 LLVDEHGNL--KVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWS 193 L DE+ NL K+ DFG + LK Q L T C T Y APE++N+ GYD E D+WS Sbjct: 551 LFTDENDNLEIKIIDFGFARLKPPDNQP--LKTPCFTLHYAAPELLNQNGYD-ESCDLWS 607 Query: 194 CGVILFVLLAGYLPFQD-------SNLMEMYRKISKGDVRY--PQW--FSSDARKLLCRL 340 GVIL+ +L+G +PFQ ++ +E+ +KI KGD + W S +A+ L+ L Sbjct: 608 LGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKDLIQGL 667 Query: 341 LDPNPNTRITMDKLIEHPWFKKG 409 L +PN R+ M L + W + G Sbjct: 668 LTVDPNKRLKMSGLRYNEWLQDG 690 Score = 74.3 bits (181), Expect = 3e-13 Identities = 48/140 (34%), Positives = 81/140 (57%), Gaps = 10/140 (7%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKA-DIWS 193 N+L+D +G++ ++DFGLS + + ++ CGT Y+AP+I+ +KA D WS Sbjct: 182 NILLDSNGHVVLTDFGLSKEFVADETERA-YSFCGTIEYMAPDIVRGGDSGHDKAVDWWS 240 Query: 194 CGVILFVLLAGYLPF----QDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNT 361 GV+++ LL G PF + ++ E+ R+I K + YPQ S+ A+ L+ RLL +P Sbjct: 241 LGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKDLIQRLLMKDPKK 300 Query: 362 RI-----TMDKLIEHPWFKK 406 R+ D++ EH +F+K Sbjct: 301 RLGCGPRDADEIKEHLFFQK 320
>SCK1_SCHPO (P50530) Serine/threonine-protein kinase sck1 (EC 2.7.11.1)| Length = 696 Score = 89.4 bits (220), Expect = 9e-18 Identities = 52/134 (38%), Positives = 80/134 (59%), Gaps = 6/134 (4%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEI-INKKGYDGEKADIWS 193 N+L+D G++ + DFGLS K + +T CGT Y+APE+ + KGY ++ D WS Sbjct: 433 NILLDADGHIALCDFGLS--KANLSANATTNTFCGTTEYLAPEVLLEDKGYT-KQVDFWS 489 Query: 194 CGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQW-FSSDARKLLCRLLDPNPNTRI- 367 GV++F + G+ PF ++ +MYR I+ G VR+P+ SS+ R + LL+ NPN R+ Sbjct: 490 LGVLVFEMCCGWSPFYAPDVQQMYRNIAFGKVRFPKGVLSSEGRSFVRGLLNRNPNHRLG 549 Query: 368 ---TMDKLIEHPWF 400 +L EHP+F Sbjct: 550 AVADTTELKEHPFF 563
>KCC1B_HUMAN (Q6P2M8) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase) Length = 343 Score = 89.4 bits (220), Expect = 9e-18 Identities = 47/126 (37%), Positives = 71/126 (56%), Gaps = 4/126 (3%) Frame = +2 Query: 32 EHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSCGVILF 211 E + VSDFGLS ++ +L T CGTP YVAPE++ +K Y G+ D+W+ GVI + Sbjct: 149 EDSKIMVSDFGLSKIQA----GNMLGTACGTPGYVAPELLEQKPY-GKAVDVWALGVISY 203 Query: 212 VLLAGYLPFQDSNLMEMYRKISKGDVRY--PQW--FSSDARKLLCRLLDPNPNTRITMDK 379 +LL GY PF D + E++ +I + + P W S A+ + LL+ +P R T + Sbjct: 204 ILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDFIRHLLERDPQKRFTCQQ 263 Query: 380 LIEHPW 397 + H W Sbjct: 264 ALRHLW 269
>LOK_DROME (O61267) Ovarian-specific serine/threonine-protein kinase Lok (EC| 2.7.11.1) (Protein loki) (dMNK) Length = 476 Score = 89.4 bits (220), Expect = 9e-18 Identities = 52/131 (39%), Positives = 75/131 (57%), Gaps = 6/131 (4%) Frame = +2 Query: 29 DEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDG--EKADIWSCGV 202 DE LKVSDFGLS + +D ++ T CGTP YVAPE++ G + +K DIWS GV Sbjct: 315 DEETLLKVSDFGLSKFVQ---KDSVMRTLCGTPLYVAPEVLITGGREAYTKKVDIWSLGV 371 Query: 203 ILFVLLAGYLPFQDSNLMEMYRKISKGDVRY--PQW--FSSDARKLLCRLLDPNPNTRIT 370 +LF L+G LPF D ++I KG Y P W S A+ L+ ++L +P R + Sbjct: 372 VLFTCLSGTLPFSDEYGTPAAQQIKKGRFAYGHPSWKSVSQRAKLLINQMLIVDPERRPS 431 Query: 371 MDKLIEHPWFK 403 +D +++ W + Sbjct: 432 IDDVLQSSWLR 442
>KPCE_RAT (P09216) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 737 Score = 89.4 bits (220), Expect = 9e-18 Identities = 48/142 (33%), Positives = 80/142 (56%), Gaps = 12/142 (8%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLH-----TTCGTPAYVAPEIINKKGYDGEKA 181 N+L+D G+ K++DFG+ ++G+L+ T CGTP Y+APEI+ + Y G Sbjct: 537 NILLDAEGHSKLADFGMC-------KEGILNGVTTTTFCGTPDYIAPEILQELEY-GPSV 588 Query: 182 DIWSCGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNT 361 D W+ GV+++ ++AG PF+ N +++ I DV YP W S +A +L + NP+ Sbjct: 589 DWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFMTKNPHK 648 Query: 362 RITM-------DKLIEHPWFKK 406 R+ D + +HP+FK+ Sbjct: 649 RLGCVAAQNGEDAIKQHPFFKE 670
>KCC2A_MOUSE (P11798) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 89.0 bits (219), Expect = 1e-17 Identities = 46/122 (37%), Positives = 76/122 (62%), Gaps = 4/122 (3%) Frame = +2 Query: 44 LKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSCGVILFVLLA 223 +K++DFGL+ E ++Q GTP Y++PE++ K Y G+ D+W+CGVIL++LL Sbjct: 152 VKLADFGLAIEVEGEQQRWF--GFAGTPGYLSPEVLRKDPY-GKPVDLWACGVILYILLV 208 Query: 224 GYLPFQDSNLMEMYRKISKG--DVRYPQW--FSSDARKLLCRLLDPNPNTRITMDKLIEH 391 GY PF D + +Y++I D P+W + +A+ L+ ++L NP+ RIT + ++H Sbjct: 209 GYPPFWDEDQHRLYQQIKARAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKH 268 Query: 392 PW 397 PW Sbjct: 269 PW 270
>CDS1_SCHPO (Q09170) Serine/threonine-protein kinase cds1 (EC 2.7.11.1)| (Checkpoint kinase cds1) Length = 460 Score = 89.0 bits (219), Expect = 1e-17 Identities = 53/140 (37%), Positives = 76/140 (54%), Gaps = 12/140 (8%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKK------GYDGEK 178 N+L+ +LK+SDFGL+ K L T CGT Y+APE++ K GYD +K Sbjct: 299 NILITNDFHLKISDFGLA--KVIHGTGTFLETFCGTMGYLAPEVLKSKNVNLDGGYD-DK 355 Query: 179 ADIWSCGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYP------QWFSSDARKLLCRL 340 DIWS G +L+V+L +PF S+ + ISKG YP S + L+ R+ Sbjct: 356 VDIWSLGCVLYVMLTASIPFASSSQAKCIELISKG--AYPIEPLLENEISEEGIDLINRM 413 Query: 341 LDPNPNTRITMDKLIEHPWF 400 L+ NP RI+ + ++HPWF Sbjct: 414 LEINPEKRISESEALQHPWF 433
>TRIB2_PONPY (Q5R669) Tribbles homolog 2 (TRB-2)| Length = 343 Score = 88.6 bits (218), Expect = 2e-17 Identities = 41/107 (38%), Positives = 62/107 (57%), Gaps = 1/107 (0%) Frame = +2 Query: 95 DGLLHTTCGTPAYVAPEIINKKG-YDGEKADIWSCGVILFVLLAGYLPFQDSNLMEMYRK 271 D L G PAYV+PEI+N G Y G+ AD+WS GV+L+ +L G PF D ++ K Sbjct: 206 DDSLSDKHGCPAYVSPEILNTSGSYSGKAADVWSLGVMLYTMLVGRYPFHDIEPSSLFSK 265 Query: 272 ISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMDKLIEHPWFKKGY 412 I +G P+ S A+ L+ +L P+ R+T ++++HPWF + Sbjct: 266 IRRGQFNIPETLSPKAKCLIRSILRREPSERLTSQEILDHPWFSTDF 312
>TRIB2_MOUSE (Q8K4K3) Tribbles homolog 2 (TRB-2)| Length = 343 Score = 88.6 bits (218), Expect = 2e-17 Identities = 41/107 (38%), Positives = 62/107 (57%), Gaps = 1/107 (0%) Frame = +2 Query: 95 DGLLHTTCGTPAYVAPEIINKKG-YDGEKADIWSCGVILFVLLAGYLPFQDSNLMEMYRK 271 D L G PAYV+PEI+N G Y G+ AD+WS GV+L+ +L G PF D ++ K Sbjct: 206 DDSLSDKHGCPAYVSPEILNTSGSYSGKAADVWSLGVMLYTMLVGRYPFHDIEPSSLFSK 265 Query: 272 ISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMDKLIEHPWFKKGY 412 I +G P+ S A+ L+ +L P+ R+T ++++HPWF + Sbjct: 266 IRRGQFNIPETLSPKAKCLIRSILRREPSERLTSQEILDHPWFSTDF 312
>TRIB2_HUMAN (Q92519) Tribbles homolog 2 (TRB-2)| Length = 343 Score = 88.6 bits (218), Expect = 2e-17 Identities = 41/107 (38%), Positives = 62/107 (57%), Gaps = 1/107 (0%) Frame = +2 Query: 95 DGLLHTTCGTPAYVAPEIINKKG-YDGEKADIWSCGVILFVLLAGYLPFQDSNLMEMYRK 271 D L G PAYV+PEI+N G Y G+ AD+WS GV+L+ +L G PF D ++ K Sbjct: 206 DDSLSDKHGCPAYVSPEILNTSGSYSGKAADVWSLGVMLYTMLVGRYPFHDIEPSSLFSK 265 Query: 272 ISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMDKLIEHPWFKKGY 412 I +G P+ S A+ L+ +L P+ R+T ++++HPWF + Sbjct: 266 IRRGQFNIPETLSPKAKCLIRSILRREPSERLTSQEILDHPWFSTDF 312
>TRIB2_CANFA (Q28283) Tribbles homolog 2 (TRB-2)| Length = 343 Score = 88.6 bits (218), Expect = 2e-17 Identities = 41/107 (38%), Positives = 62/107 (57%), Gaps = 1/107 (0%) Frame = +2 Query: 95 DGLLHTTCGTPAYVAPEIINKKG-YDGEKADIWSCGVILFVLLAGYLPFQDSNLMEMYRK 271 D L G PAYV+PEI+N G Y G+ AD+WS GV+L+ +L G PF D ++ K Sbjct: 206 DDSLSDKHGCPAYVSPEILNTSGSYSGKAADVWSLGVMLYTMLVGRYPFHDIEPSSLFSK 265 Query: 272 ISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMDKLIEHPWFKKGY 412 I +G P+ S A+ L+ +L P+ R+T ++++HPWF + Sbjct: 266 IRRGQFNIPETLSPKAKCLIRSILRREPSERLTSQEILDHPWFSTDF 312
>TRIB2_BOVIN (Q5GLH2) Tribbles homolog 2 (TRB-2)| Length = 343 Score = 88.6 bits (218), Expect = 2e-17 Identities = 41/107 (38%), Positives = 62/107 (57%), Gaps = 1/107 (0%) Frame = +2 Query: 95 DGLLHTTCGTPAYVAPEIINKKG-YDGEKADIWSCGVILFVLLAGYLPFQDSNLMEMYRK 271 D L G PAYV+PEI+N G Y G+ AD+WS GV+L+ +L G PF D ++ K Sbjct: 206 DDSLSDKHGCPAYVSPEILNTNGSYSGKAADVWSLGVMLYTMLVGRYPFHDIEPSSLFSK 265 Query: 272 ISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMDKLIEHPWFKKGY 412 I +G P+ S A+ L+ +L P+ R+T ++++HPWF + Sbjct: 266 IRRGQFNIPETLSPKAKCLIRSILRREPSERLTSQEILDHPWFSTDF 312
>KPCT_HUMAN (Q04759) Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)| Length = 706 Score = 88.6 bits (218), Expect = 2e-17 Identities = 46/131 (35%), Positives = 75/131 (57%), Gaps = 1/131 (0%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 N+L+D+ G++K++DFG+ KE D +T CGTP Y+APEI+ + Y+ D WS Sbjct: 509 NILLDKDGHIKIADFGMC--KENMLGDAKTNTFCGTPDYIAPEILLGQKYN-HSVDWWSF 565 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRI-TM 373 GV+L+ +L G PF + E++ I + YP+W +A+ LL +L P R+ Sbjct: 566 GVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWLEKEAKDLLVKLFVREPEKRLGVR 625 Query: 374 DKLIEHPWFKK 406 + +HP F++ Sbjct: 626 GDIRQHPLFRE 636
>TSSK2_MOUSE (O54863) Testis-specific serine/threonine-protein kinase 2 (EC| 2.7.11.1) (TSSK-2) (Testis-specific kinase 2) (TSK-2) (Serine/threonine-protein kinase 22B) Length = 357 Score = 88.6 bits (218), Expect = 2e-17 Identities = 48/140 (34%), Positives = 83/140 (59%), Gaps = 3/140 (2%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLS--ALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIW 190 NLL+D+ N+K+SDFG S L++ + L T CG+ AY APE+ Y + DIW Sbjct: 141 NLLLDKDFNIKLSDFGFSKGCLRDGSGRIVLSKTFCGSAAYAAPEVRQGIPYQPKVYDIW 200 Query: 191 SCGVILFVLLAGYLPFQDSNLMEM-YRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRI 367 S GVIL++++ G +P+ DS++ ++ +K + D + + + + L+ R+L P+ N R+ Sbjct: 201 SLGVILYIMVCGSMPYDDSDIKKLRIQKEHRVDFPRSKNLTGECKDLIYRILQPDVNRRL 260 Query: 368 TMDKLIEHPWFKKGYKPAVM 427 +D+++ H W + KP M Sbjct: 261 HIDEILSHSWLQPP-KPKAM 279
>AKT1_BOVIN (Q01314) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) Length = 480 Score = 88.2 bits (217), Expect = 2e-17 Identities = 42/117 (35%), Positives = 71/117 (60%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NL++D+ G++K++DFGL KE K + T CGTP Y+APE++ Y G D W Sbjct: 279 NLMLDKDGHIKITDFGLC--KEGIKDGATMKTFCGTPEYLAPEVLEDNDY-GRAVDWWGL 335 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRI 367 GV+++ ++ G LPF + + +++ I ++R+P+ S +A+ LL LL +P R+ Sbjct: 336 GVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLSPEAKSLLSGLLKKDPKQRL 392
>KPCL_RAT (Q64617) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 683 Score = 87.8 bits (216), Expect = 3e-17 Identities = 47/137 (34%), Positives = 76/137 (55%), Gaps = 7/137 (5%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTT-CGTPAYVAPEIINKKGYDGEKADIWS 193 N+L+D G+ K++DFG+ C +G+ T CGTP Y+APEI+ + Y G D W+ Sbjct: 484 NVLLDHEGHCKLADFGMCKEGIC---NGVTTATFCGTPDYIAPEILQEMLY-GPAVDWWA 539 Query: 194 CGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITM 373 GV+L+ +L G+ PF+ N +++ I +V YP W DA +L + NP R+ Sbjct: 540 MGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHEDATGILKSFMTKNPTMRLGS 599 Query: 374 ------DKLIEHPWFKK 406 +++ HP+FK+ Sbjct: 600 LTQGGEHEILRHPFFKE 616
>HUNK_MOUSE (O88866) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) (Serine/threonine-protein kinase MAK-V) Length = 714 Score = 87.8 bits (216), Expect = 3e-17 Identities = 50/135 (37%), Positives = 74/135 (54%), Gaps = 3/135 (2%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+DE N+K+ DFGLS T CG+PAY APE++ +K Y G K D+WS Sbjct: 191 NLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLARKKY-GPKIDVWSI 249 Query: 197 GVILFVLLAGYLPF--QDSNLMEMYRK-ISKGDVRYPQWFSSDARKLLCRLLDPNPNTRI 367 GV ++ +L G LPF + +L +Y+K + K P S+ A L LL+P+P R Sbjct: 250 GVNMYAMLTGTLPFTVEPFSLRALYQKMVDKAMNPLPTQLSTGAVNFLRSLLEPDPVKRP 309 Query: 368 TMDKLIEHPWFKKGY 412 + + + + W + Y Sbjct: 310 NIQQALANRWLNENY 324
>SNRK_HUMAN (Q9NRH2) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 765 Score = 87.4 bits (215), Expect = 3e-17 Identities = 46/125 (36%), Positives = 71/125 (56%) Frame = +2 Query: 29 DEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSCGVIL 208 ++ G +K++DFG S + K+ L T+CG+ AY APEI+ YD DIWS GVIL Sbjct: 149 EKQGLVKLTDFGFSNKFQPGKK---LTTSCGSLAYSAPEILLGDEYDAPAVDIWSLGVIL 205 Query: 209 FVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMDKLIE 388 F+L+ G PFQ++N E I P S + + L+ R+L +P R +++++ Sbjct: 206 FMLVCGQPPFQEANDSETLTMIMDCKYTVPSHVSKECKDLITRMLQRDPKRRASLEEIEN 265 Query: 389 HPWFK 403 HPW + Sbjct: 266 HPWLQ 270
>HUNK_PANTR (Q68UT7) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) Length = 714 Score = 87.4 bits (215), Expect = 3e-17 Identities = 49/135 (36%), Positives = 75/135 (55%), Gaps = 3/135 (2%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+DE N+K+ DFGLS T CG+PAY APE++ +K Y G K D+WS Sbjct: 191 NLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLARKKY-GPKIDVWSI 249 Query: 197 GVILFVLLAGYLPF--QDSNLMEMYRKISKGDVR-YPQWFSSDARKLLCRLLDPNPNTRI 367 GV ++ +L G LPF + +L +Y+K+ ++ P S+ A L LL+P+P R Sbjct: 250 GVNMYAMLTGTLPFTVEPFSLRALYQKMVDKEMNPLPTQLSTGAISFLRSLLEPDPVKRP 309 Query: 368 TMDKLIEHPWFKKGY 412 + + + + W + Y Sbjct: 310 NIQQALANRWLNENY 324
>HUNK_HUMAN (P57058) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) (Serine/threonine-protein kinase MAK-V) (B19) Length = 714 Score = 87.4 bits (215), Expect = 3e-17 Identities = 49/135 (36%), Positives = 75/135 (55%), Gaps = 3/135 (2%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+DE N+K+ DFGLS T CG+PAY APE++ +K Y G K D+WS Sbjct: 191 NLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLARKKY-GPKIDVWSI 249 Query: 197 GVILFVLLAGYLPF--QDSNLMEMYRKISKGDVR-YPQWFSSDARKLLCRLLDPNPNTRI 367 GV ++ +L G LPF + +L +Y+K+ ++ P S+ A L LL+P+P R Sbjct: 250 GVNMYAMLTGTLPFTVEPFSLRALYQKMVDKEMNPLPTQLSTGAISFLRSLLEPDPVKRP 309 Query: 368 TMDKLIEHPWFKKGY 412 + + + + W + Y Sbjct: 310 NIQQALANRWLNENY 324
>AKT2_RAT (P47197) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 87.4 bits (215), Expect = 3e-17 Identities = 44/133 (33%), Positives = 76/133 (57%), Gaps = 5/133 (3%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NL++D+ G++K++DFGLS KE + T CGTP Y+APE++ Y G D W Sbjct: 280 NLMLDKDGHIKITDFGLS--KEGISDGATMKTFCGTPEYLAPEVLEDNDY-GRAVDWWGL 336 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRI--- 367 GV+++ ++ G LPF + + ++ I ++R+P+ +A+ LL LL +P R+ Sbjct: 337 GVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLGPEAKSLLAGLLKKDPKQRLGGG 396 Query: 368 --TMDKLIEHPWF 400 +++EH +F Sbjct: 397 PSDAKEVMEHRFF 409
>KPCL_HUMAN (P24723) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 682 Score = 87.0 bits (214), Expect = 5e-17 Identities = 47/137 (34%), Positives = 75/137 (54%), Gaps = 7/137 (5%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTT-CGTPAYVAPEIINKKGYDGEKADIWS 193 N+L+D G+ K++DFG+ C +G+ T CGTP Y+APEI+ + Y G D W+ Sbjct: 483 NVLLDHEGHCKLADFGMCKEGIC---NGVTTATFCGTPDYIAPEILQEMLY-GPAVDWWA 538 Query: 194 CGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITM 373 GV+L+ +L G+ PF+ N +++ I +V YP W DA +L + NP R+ Sbjct: 539 MGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHEDATGILKSFMTKNPTMRLGS 598 Query: 374 ------DKLIEHPWFKK 406 ++ HP+FK+ Sbjct: 599 LTQGGEHAILRHPFFKE 615
>CDPK_SOYBN (P28583) Calcium-dependent protein kinase SK5 (EC 2.7.11.1) (CDPK)| Length = 508 Score = 87.0 bits (214), Expect = 5e-17 Identities = 49/128 (38%), Positives = 72/128 (56%), Gaps = 4/128 (3%) Frame = +2 Query: 26 VDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSCGVI 205 +DE LK +DFGLS K G+P YVAPE++ K G ++D+WS GVI Sbjct: 169 IDEDAKLKATDFGLSVF---YKPGESFCDVVGSPYYVAPEVLRK--LYGPESDVWSAGVI 223 Query: 206 LFVLLAGYLPFQDSNLMEMYRKISKG--DVRYPQW--FSSDARKLLCRLLDPNPNTRITM 373 L++LL+G PF + ++R+I G D W S A+ L+ ++LD NP TR+T Sbjct: 224 LYILLSGVPPFWAESEPGIFRQILLGKLDFHSEPWPSISDSAKDLIRKMLDQNPKTRLTA 283 Query: 374 DKLIEHPW 397 +++ HPW Sbjct: 284 HEVLRHPW 291
>AKT2_HUMAN (P31751) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 87.0 bits (214), Expect = 5e-17 Identities = 44/133 (33%), Positives = 76/133 (57%), Gaps = 5/133 (3%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NL++D+ G++K++DFGL KE + T CGTP Y+APE++ Y G D W Sbjct: 280 NLMLDKDGHIKITDFGLC--KEGISDGATMKTFCGTPEYLAPEVLEDNDY-GRAVDWWGL 336 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRI--- 367 GV+++ ++ G LPF + + ++ I ++R+P+ S +A+ LL LL +P R+ Sbjct: 337 GVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGG 396 Query: 368 --TMDKLIEHPWF 400 +++EH +F Sbjct: 397 PSDAKEVMEHRFF 409
>SNRK_MOUSE (Q8VDU5) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 748 Score = 87.0 bits (214), Expect = 5e-17 Identities = 47/125 (37%), Positives = 71/125 (56%) Frame = +2 Query: 29 DEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSCGVIL 208 ++ G +K++DFG S + K+ L T+CG+ AY APEI+ YD DIWS GVIL Sbjct: 149 EKQGLVKLTDFGFSNKFQPGKK---LTTSCGSLAYSAPEILLGDEYDAPAVDIWSLGVIL 205 Query: 209 FVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMDKLIE 388 F+L+ G PFQ++N E I P S+ R L+ R+L +P R +++++ Sbjct: 206 FMLVCGQPPFQEANDSETLTMIMDCKYTVPPRVSAGCRDLITRMLQRDPKRRASLEEIES 265 Query: 389 HPWFK 403 HPW + Sbjct: 266 HPWLQ 270
>KS6A5_CHICK (Q5F3L1) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1)| Length = 789 Score = 87.0 bits (214), Expect = 5e-17 Identities = 55/143 (38%), Positives = 78/143 (54%), Gaps = 13/143 (9%) Frame = +2 Query: 20 LLVDEHGN--LKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWS 193 L DE N +K+ DFG + LK Q L T C T Y APE+ N GYD E D+WS Sbjct: 541 LFTDETDNSEIKIIDFGFARLKPPDNQP--LKTPCFTLHYAAPELFNHNGYD-ESCDLWS 597 Query: 194 CGVILFVLLAGYLPFQD-------SNLMEMYRKISKGDVRY--PQW--FSSDARKLLCRL 340 GVIL+ +L+G +PFQ ++ +E+ +KI KG+ + W S +A++L+ L Sbjct: 598 LGVILYTMLSGQVPFQSQDKSLTCTSALEIMKKIKKGEFSFEGEAWKNVSEEAKELIQGL 657 Query: 341 LDPNPNTRITMDKLIEHPWFKKG 409 L +PN RI M L + W + G Sbjct: 658 LTVDPNKRIKMSSLRYNEWLQDG 680 Score = 73.2 bits (178), Expect = 7e-13 Identities = 45/139 (32%), Positives = 81/139 (58%), Gaps = 10/139 (7%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKA-DIWS 193 N+L+D G++ ++DFGLS + ++ ++ CGT Y+AP+I+ +KA D WS Sbjct: 172 NILLDSDGHVVLTDFGLSK-EFLTDENERAYSFCGTIEYMAPDIVRGGDTGHDKAVDWWS 230 Query: 194 CGVILFVLLAGYLPF----QDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNT 361 GV+++ LL G PF + ++ E+ R+I K + YPQ S+ ++ ++ RLL +P Sbjct: 231 VGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALSKDIIQRLLMKDPKK 290 Query: 362 RI-----TMDKLIEHPWFK 403 R+ D++ +HP+F+ Sbjct: 291 RLGCGPTDADEIKQHPFFQ 309
>AURKB_HUMAN (Q96GD4) Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-| and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (Aurora-related kinase 2) (STK-1) (Aurora-B) Length = 344 Score = 87.0 bits (214), Expect = 5e-17 Identities = 46/129 (35%), Positives = 76/129 (58%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NLL+ G LK++DFG S ++ T CGT Y+ PE+I + ++ EK D+W Sbjct: 205 NLLLGLKGELKIADFGWSVHAPSLRRK----TMCGTLDYLPPEMIEGRMHN-EKVDLWCI 259 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMD 376 GV+ + LL G PF+ ++ E YR+I K D+++P + A+ L+ +LL NP+ R+ + Sbjct: 260 GVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPTGAQDLISKLLRHNPSERLPLA 319 Query: 377 KLIEHPWFK 403 ++ HPW + Sbjct: 320 QVSAHPWVR 328
>SNRK_RAT (Q63553) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 746 Score = 87.0 bits (214), Expect = 5e-17 Identities = 47/125 (37%), Positives = 71/125 (56%) Frame = +2 Query: 29 DEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSCGVIL 208 ++ G +K++DFG S + K+ L T+CG+ AY APEI+ YD DIWS GVIL Sbjct: 149 EKQGLVKLTDFGFSNKFQPGKK---LTTSCGSLAYSAPEILLGDEYDAPAVDIWSLGVIL 205 Query: 209 FVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRITMDKLIE 388 F+L+ G PFQ++N E I P S+ R L+ R+L +P R +++++ Sbjct: 206 FMLVCGQPPFQEANDSETLTMIMDCKYTVPPRVSAGCRDLITRMLQRDPKRRASLEEIES 265 Query: 389 HPWFK 403 HPW + Sbjct: 266 HPWLQ 270
>KS6A5_PONPY (Q5R4K3) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1)| Length = 802 Score = 86.7 bits (213), Expect = 6e-17 Identities = 55/143 (38%), Positives = 79/143 (55%), Gaps = 13/143 (9%) Frame = +2 Query: 20 LLVDEHGNL--KVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWS 193 L DE+ NL K+ DFG + K Q L T C T Y APE++N+ GYD E D+WS Sbjct: 551 LFTDENDNLEIKIIDFGFARPKPPDNQP--LKTPCFTLHYAAPELLNQNGYD-ESCDLWS 607 Query: 194 CGVILFVLLAGYLPFQD-------SNLMEMYRKISKGDVRY--PQW--FSSDARKLLCRL 340 GVIL+ +L+G +PFQ ++ +E+ +KI KGD + W S +A+ L+ L Sbjct: 608 LGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKDLIQGL 667 Query: 341 LDPNPNTRITMDKLIEHPWFKKG 409 L +PN R+ M L + W + G Sbjct: 668 LTVDPNKRLKMSGLRYNEWLQDG 690 Score = 72.8 bits (177), Expect = 9e-13 Identities = 47/140 (33%), Positives = 80/140 (57%), Gaps = 10/140 (7%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKA-DIWS 193 N+L+D +G++ ++DFGLS + + ++ CGT Y+AP+I+ +KA D WS Sbjct: 182 NILLDSNGHVMLTDFGLSKEFVADETERA-YSFCGTIEYMAPDIVRGGDSGHDKAVDWWS 240 Query: 194 CGVILFVLLAGYLPF----QDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNT 361 GV+++ LL G PF + ++ E+ R+I K + YPQ S+ A+ L+ LL +P Sbjct: 241 LGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKDLIQHLLMKDPKK 300 Query: 362 RI-----TMDKLIEHPWFKK 406 R+ D++ EH +F+K Sbjct: 301 RLGCGPRDADEIKEHLFFQK 320
>TSSK3_HUMAN (Q96PN8) Testis-specific serine/threonine-protein kinase 3 (EC| 2.7.11.1) (TSSK-3) (Testis-specific kinase 3) (TSK-3) (Serine/threonine-protein kinase 22C) Length = 268 Score = 86.7 bits (213), Expect = 6e-17 Identities = 46/121 (38%), Positives = 76/121 (62%), Gaps = 2/121 (1%) Frame = +2 Query: 41 NLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSCGVILFVLL 220 NLK++DFG + + ++ L T CG+ AY APE++ +D +K D+WS GV+L+V+L Sbjct: 146 NLKLTDFGFAKVLPKSHRE-LSQTFCGSTAYAAPEVLQGIPHDSKKGDVWSMGVVLYVML 204 Query: 221 AGYLPFQDSNLMEMYRKISKGDVRYPQW--FSSDARKLLCRLLDPNPNTRITMDKLIEHP 394 LPF D+++ +M + KG V +P S+D + LL RLL+P+ R +++++ HP Sbjct: 205 CASLPFDDTDIPKMLWQQQKG-VSFPTHLSISADCQDLLKRLLEPDMILRPSIEEVSWHP 263 Query: 395 W 397 W Sbjct: 264 W 264
>KS6A5_MOUSE (Q8C050) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RLSK) Length = 863 Score = 86.7 bits (213), Expect = 6e-17 Identities = 56/143 (39%), Positives = 78/143 (54%), Gaps = 13/143 (9%) Frame = +2 Query: 20 LLVDEHGNL--KVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWS 193 L DE+ NL KV DFG + LK Q L T C T Y APE++ GYD E D+WS Sbjct: 615 LFTDENDNLEIKVIDFGFARLKPPDNQP--LKTPCFTLHYAAPELLTHNGYD-ESCDLWS 671 Query: 194 CGVILFVLLAGYLPFQD-------SNLMEMYRKISKGDVRY--PQW--FSSDARKLLCRL 340 GVIL+ +L+G +PFQ ++ +E+ +KI KGD + W S +A+ L+ L Sbjct: 672 LGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKDLIQGL 731 Query: 341 LDPNPNTRITMDKLIEHPWFKKG 409 L +PN R+ M L + W + G Sbjct: 732 LTVDPNKRLKMSGLRYNEWLQDG 754 Score = 73.9 bits (180), Expect = 4e-13 Identities = 48/140 (34%), Positives = 81/140 (57%), Gaps = 10/140 (7%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKA-DIWS 193 N+L+D +G++ ++DFGLS + + ++ CGT Y+AP+I+ +KA D WS Sbjct: 181 NILLDSNGHVVLTDFGLSKEFVADETERA-YSFCGTIEYMAPDIVRGGDSGHDKAVDWWS 239 Query: 194 CGVILFVLLAGYLPF----QDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNT 361 GV+++ LL G PF + ++ E+ R+I K + YPQ S+ A+ LL RLL +P Sbjct: 240 LGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSTVAKDLLQRLLMKDPKK 299 Query: 362 RI-----TMDKLIEHPWFKK 406 R+ +++ EH +F+K Sbjct: 300 RLGCGPRDAEEIKEHLFFEK 319
>AKT_MLVAT (P31748) AKT kinase transforming protein (EC 2.7.11.1)| Length = 501 Score = 86.7 bits (213), Expect = 6e-17 Identities = 41/117 (35%), Positives = 70/117 (59%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NL++D+ G++K++DFGL KE K + T CGTP Y+APE++ Y G D W Sbjct: 300 NLMLDKDGHIKITDFGLC--KEGIKDGATMKTFCGTPEYLAPEVLEDNDY-GRAVDWWGL 356 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRI 367 GV+++ ++ G LPF + + +++ I ++R+P+ +A+ LL LL +P R+ Sbjct: 357 GVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPTQRL 413
>KPSH1_PINFU (Q4KTY1) Serine/threonine-protein kinase H1 homolog (EC 2.7.11.1)| Length = 415 Score = 86.7 bits (213), Expect = 6e-17 Identities = 56/178 (31%), Positives = 93/178 (52%), Gaps = 8/178 (4%) Frame = +2 Query: 17 NLLVDEHGN---LKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADI 187 NLL G+ + ++DFGLS+ ++ + + TTCGTP Y+APEII +K Y + D+ Sbjct: 203 NLLYYHPGHDSKIMITDFGLSSTRK--GPENFMRTTCGTPEYIAPEIIARKPYMCQ-VDM 259 Query: 188 WSCGVILFVLLAGYLPFQDSNLMEMYRKISKGDVRY--PQW--FSSDARKLLCRLLDPNP 355 W+ GVI ++LL+G +PF D N +YR I K Y W S+ A+ + +LL +P Sbjct: 260 WAVGVITYILLSGTMPFDDENKTRLYRLILKAKYSYAGEHWKDVSAQAKDFIDKLLVVSP 319 Query: 356 NTRITMDKLIEHPWFKKGYKPAVMLGTPRA-SKDLNDVQAAFSTDHKDGEGSRAEQPN 526 R++ ++H W + R S++L Q+ + K + +R+ + N Sbjct: 320 GDRLSAADALKHQWLISNAASSSNKNLHRTISQNLIHRQSTRANSTKSAKSTRSTKSN 377
>AKT1_RAT (P47196) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) Length = 480 Score = 86.7 bits (213), Expect = 6e-17 Identities = 41/117 (35%), Positives = 70/117 (59%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NL++D+ G++K++DFGL KE K + T CGTP Y+APE++ Y G D W Sbjct: 279 NLMLDKDGHIKITDFGLC--KEGIKDGATMKTFCGTPEYLAPEVLEDNDY-GRAVDWWGL 335 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRI 367 GV+++ ++ G LPF + + +++ I ++R+P+ +A+ LL LL +P R+ Sbjct: 336 GVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPTQRL 392
>AKT1_HUMAN (P31749) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) (C-AKT) Length = 480 Score = 86.7 bits (213), Expect = 6e-17 Identities = 41/117 (35%), Positives = 70/117 (59%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 NL++D+ G++K++DFGL KE K + T CGTP Y+APE++ Y G D W Sbjct: 279 NLMLDKDGHIKITDFGLC--KEGIKDGATMKTFCGTPEYLAPEVLEDNDY-GRAVDWWGL 335 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRI 367 GV+++ ++ G LPF + + +++ I ++R+P+ +A+ LL LL +P R+ Sbjct: 336 GVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRL 392
>KPCT_MOUSE (Q02111) Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)| Length = 707 Score = 86.7 bits (213), Expect = 6e-17 Identities = 45/131 (34%), Positives = 74/131 (56%), Gaps = 1/131 (0%) Frame = +2 Query: 17 NLLVDEHGNLKVSDFGLSALKECQKQDGLLHTTCGTPAYVAPEIINKKGYDGEKADIWSC 196 N+L+D G++K++DFG+ KE D +T CGTP Y+APEI+ + Y+ D WS Sbjct: 509 NILLDRDGHIKIADFGMC--KENMLGDAKTNTFCGTPDYIAPEILLGQKYN-HSVDWWSF 565 Query: 197 GVILFVLLAGYLPFQDSNLMEMYRKISKGDVRYPQWFSSDARKLLCRLLDPNPNTRI-TM 373 GV+++ +L G PF + E++ I + YP+W +A+ LL +L P R+ Sbjct: 566 GVLVYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWLEREAKDLLVKLFVREPEKRLGVR 625 Query: 374 DKLIEHPWFKK 406 + +HP F++ Sbjct: 626 GDIRQHPLFRE 636 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 110,486,111 Number of Sequences: 219361 Number of extensions: 2550346 Number of successful extensions: 10439 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 8284 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 8777 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 6541540170 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
