ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | baal29f21 |
|---|---|
| Clone Library Name | barley_pub |
>KC1D_ARATH (P42158) Casein kinase I isoform delta-like (EC 2.7.11.1)| (CKI-delta) Length = 450 Score = 288 bits (737), Expect = 8e-78 Identities = 136/152 (89%), Positives = 149/152 (98%) Frame = +2 Query: 131 MEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQ 310 MEPRVGNK+RLGRK+GSGSFGEIYLGTN+ TNEE+AIKLENVKTKHPQLLYESKLYR+LQ Sbjct: 1 MEPRVGNKFRLGRKIGSGSFGEIYLGTNIHTNEELAIKLENVKTKHPQLLYESKLYRILQ 60 Query: 311 GGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIH 490 GGTG+ NVKWFGVEGDYNVLVMD+LGPSLEDLF+FC+RKLSLK+VLMLADQMINRVEF H Sbjct: 61 GGTGVPNVKWFGVEGDYNVLVMDLLGPSLEDLFNFCSRKLSLKSVLMLADQMINRVEFFH 120 Query: 491 SKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 SKSFLHRD+KPDNFLMGLG+RANQVY+IDFGL Sbjct: 121 SKSFLHRDLKPDNFLMGLGRRANQVYIIDFGL 152
>KC1_TOXGO (Q6QNM1) Casein kinase I (EC 2.7.11.1)| Length = 324 Score = 248 bits (634), Expect = 7e-66 Identities = 114/152 (75%), Positives = 138/152 (90%) Frame = +2 Query: 131 MEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQ 310 ME RVG KYRLGRK+GSGSFG+IY+G N+ T +EVAIKLE++K+KHPQLLYESKLY++L Sbjct: 1 MEVRVGGKYRLGRKIGSGSFGDIYIGANILTGDEVAIKLESIKSKHPQLLYESKLYKLLA 60 Query: 311 GGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIH 490 GG GI V W+G+EGDYNV+V+D+LGPSLEDLFS CNRKLSLKTVLMLADQM+NR+EF+H Sbjct: 61 GGIGIPMVHWYGIEGDYNVMVIDLLGPSLEDLFSICNRKLSLKTVLMLADQMLNRIEFVH 120 Query: 491 SKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 SK+F+HRDIKPDNFL+G GK+ + VY+IDFGL Sbjct: 121 SKNFIHRDIKPDNFLIGRGKKMSVVYIIDFGL 152
>KC1E_MOUSE (Q9JMK2) Casein kinase I isoform epsilon (EC 2.7.11.1)| (CKI-epsilon) (CKIe) Length = 416 Score = 246 bits (629), Expect = 3e-65 Identities = 114/152 (75%), Positives = 137/152 (90%) Frame = +2 Query: 131 MEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQ 310 ME RVGNKYRLGRK+GSGSFG+IYLG N+ + EEVAIKLE VKTKHPQL ESK Y+++Q Sbjct: 1 MELRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQ 60 Query: 311 GGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIH 490 GG GI ++KW G EGDYNV+VM++LGPSLEDLF+FC+RK SLKTVL+LADQMI+R+E+IH Sbjct: 61 GGVGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH 120 Query: 491 SKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 SK+F+HRD+KPDNFLMGLGK+ N VY+IDFGL Sbjct: 121 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGL 152
>KC1E_HUMAN (P49674) Casein kinase I isoform epsilon (EC 2.7.11.1)| (CKI-epsilon) (CKIe) Length = 416 Score = 246 bits (629), Expect = 3e-65 Identities = 114/152 (75%), Positives = 137/152 (90%) Frame = +2 Query: 131 MEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQ 310 ME RVGNKYRLGRK+GSGSFG+IYLG N+ + EEVAIKLE VKTKHPQL ESK Y+++Q Sbjct: 1 MELRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQ 60 Query: 311 GGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIH 490 GG GI ++KW G EGDYNV+VM++LGPSLEDLF+FC+RK SLKTVL+LADQMI+R+E+IH Sbjct: 61 GGVGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH 120 Query: 491 SKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 SK+F+HRD+KPDNFLMGLGK+ N VY+IDFGL Sbjct: 121 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGL 152
>HHP1_SCHPO (P40235) Casein kinase I homolog hhp1 (EC 2.7.11.1)| Length = 365 Score = 245 bits (626), Expect = 6e-65 Identities = 114/152 (75%), Positives = 136/152 (89%) Frame = +2 Query: 131 MEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQ 310 ++ R+GNKYR+GRK+GSGSFG+IYLGTNV + EEVAIKLE+ + KHPQL YE ++YR+L Sbjct: 3 LDLRIGNKYRIGRKIGSGSFGDIYLGTNVVSGEEVAIKLESTRAKHPQLEYEYRVYRILS 62 Query: 311 GGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIH 490 GG GI V+WFGVE DYN +VMD+LGPSLEDLF+FCNRK SLKTVL+LADQ+I+R+EFIH Sbjct: 63 GGVGIPFVRWFGVECDYNAMVMDLLGPSLEDLFNFCNRKFSLKTVLLLADQLISRIEFIH 122 Query: 491 SKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 SKSFLHRDIKPDNFLMG+GKR NQV +IDFGL Sbjct: 123 SKSFLHRDIKPDNFLMGIGKRGNQVNIIDFGL 154
>KC1D_RAT (Q06486) Casein kinase I isoform delta (EC 2.7.11.1) (CKI-delta)| Length = 415 Score = 244 bits (623), Expect = 1e-64 Identities = 112/152 (73%), Positives = 137/152 (90%) Frame = +2 Query: 131 MEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQ 310 ME RVGN+YRLGRK+GSGSFG+IYLGT++ EEVAIKLE VKTKHPQL ESK+Y+++Q Sbjct: 1 MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQ 60 Query: 311 GGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIH 490 GG GI ++W G EGDYNV+VM++LGPSLEDLF+FC+RK SLKTVL+LADQMI+R+E+IH Sbjct: 61 GGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH 120 Query: 491 SKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 SK+F+HRD+KPDNFLMGLGK+ N VY+IDFGL Sbjct: 121 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGL 152
>KC1D_MOUSE (Q9DC28) Casein kinase I isoform delta (EC 2.7.11.1) (CKI-delta)| (CKId) Length = 415 Score = 244 bits (623), Expect = 1e-64 Identities = 112/152 (73%), Positives = 137/152 (90%) Frame = +2 Query: 131 MEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQ 310 ME RVGN+YRLGRK+GSGSFG+IYLGT++ EEVAIKLE VKTKHPQL ESK+Y+++Q Sbjct: 1 MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQ 60 Query: 311 GGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIH 490 GG GI ++W G EGDYNV+VM++LGPSLEDLF+FC+RK SLKTVL+LADQMI+R+E+IH Sbjct: 61 GGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH 120 Query: 491 SKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 SK+F+HRD+KPDNFLMGLGK+ N VY+IDFGL Sbjct: 121 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGL 152
>KC1D_HUMAN (P48730) Casein kinase I isoform delta (EC 2.7.11.1) (CKI-delta)| (CKId) Length = 415 Score = 244 bits (623), Expect = 1e-64 Identities = 112/152 (73%), Positives = 137/152 (90%) Frame = +2 Query: 131 MEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQ 310 ME RVGN+YRLGRK+GSGSFG+IYLGT++ EEVAIKLE VKTKHPQL ESK+Y+++Q Sbjct: 1 MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQ 60 Query: 311 GGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIH 490 GG GI ++W G EGDYNV+VM++LGPSLEDLF+FC+RK SLKTVL+LADQMI+R+E+IH Sbjct: 61 GGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH 120 Query: 491 SKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 SK+F+HRD+KPDNFLMGLGK+ N VY+IDFGL Sbjct: 121 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGL 152
>KIN20_CAEEL (Q20471) Casein kinase I isoform delta (EC 2.7.11.1) (Protein| kinase 20) Length = 497 Score = 243 bits (621), Expect = 2e-64 Identities = 123/192 (64%), Positives = 149/192 (77%), Gaps = 2/192 (1%) Frame = +2 Query: 17 AQTLATNLRNSSLA--QVPP*LDALNLGGGSVACVRARPPMEPRVGNKYRLGRKLGSGSF 190 A TL L + LA Q+PP L V + ME RVGN++RLGRK+GSGSF Sbjct: 152 ALTLDPTLLSHFLATQQIPPVPQPL---------VHKKAEMELRVGNRFRLGRKIGSGSF 202 Query: 191 GEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTGISNVKWFGVEGDYNVL 370 G+IYLG N+QTNEEVA+KLE VK+KHPQL ES+LYR++ GG GI ++W G EGDYNV+ Sbjct: 203 GDIYLGQNIQTNEEVAVKLECVKSKHPQLHIESRLYRIMLGGIGIPEIRWCGQEGDYNVM 262 Query: 371 VMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGK 550 VM++LGPSLEDLF+FC RK SLKTVL+LADQM++RVEFIH + ++HRDIKPDNFLMGLGK Sbjct: 263 VMELLGPSLEDLFNFCQRKFSLKTVLLLADQMLSRVEFIHCRDYIHRDIKPDNFLMGLGK 322 Query: 551 RANQVYMIDFGL 586 R N VY+IDFGL Sbjct: 323 RGNLVYIIDFGL 334
>KC1_EIMTE (Q6QNL9) Casein kinase I (EC 2.7.11.1)| Length = 335 Score = 241 bits (616), Expect = 9e-64 Identities = 108/152 (71%), Positives = 137/152 (90%) Frame = +2 Query: 131 MEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQ 310 M+ RVG KYRLGRK+GSGSFG+IYLGTN+ T +EVAIKLE+V+++HPQL+YESKLY++L Sbjct: 1 MDVRVGGKYRLGRKIGSGSFGDIYLGTNISTGDEVAIKLESVRSRHPQLIYESKLYKILT 60 Query: 311 GGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIH 490 GG GI + W+G+EGDYNV+++++LGPSLEDLFS CNRKLSLKTVLMLADQM+NR+EF+H Sbjct: 61 GGIGIPTLYWYGIEGDYNVMIIELLGPSLEDLFSICNRKLSLKTVLMLADQMLNRIEFVH 120 Query: 491 SKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 S+ F+HRDIKPDNFL+G GK+ + V+ IDFGL Sbjct: 121 SRHFIHRDIKPDNFLIGRGKKMSIVFAIDFGL 152
>DCO_DROME (O76324) Discs overgrown protein kinase (EC 2.7.11.1) (Protein| double-time) Length = 440 Score = 238 bits (607), Expect = 1e-62 Identities = 110/152 (72%), Positives = 133/152 (87%) Frame = +2 Query: 131 MEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQ 310 ME RVGNKYRLGRK+GSGSFG+IYLGT + T EEVAIKLE ++TKHPQL ESK Y+ +Q Sbjct: 1 MELRVGNKYRLGRKIGSGSFGDIYLGTTINTGEEVAIKLECIRTKHPQLHIESKFYKTMQ 60 Query: 311 GGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIH 490 GG GI + W G EGDYNV+VM++LGPSLEDLF+FC+R+ SLKTVL+LADQMI+R+++IH Sbjct: 61 GGIGIPRIIWCGSEGDYNVMVMELLGPSLEDLFNFCSRRFSLKTVLLLADQMISRIDYIH 120 Query: 491 SKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 S+ F+HRDIKPDNFLMGLGK+ N VY+IDFGL Sbjct: 121 SRDFIHRDIKPDNFLMGLGKKGNLVYIIDFGL 152
>KC1A_SHEEP (P67829) Casein kinase I isoform alpha (EC 2.7.11.1) (CKI-alpha)| (CK1) Length = 325 Score = 229 bits (583), Expect = 6e-60 Identities = 100/148 (67%), Positives = 132/148 (89%) Frame = +2 Query: 143 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 322 VG KY+L RK+GSGSFG+IYL N+ EEVA+KLE+ K +HPQLLYESKLY++LQGG G Sbjct: 13 VGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVG 72 Query: 323 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 502 I +++W+G E DYNVLVMD+LGPSLEDLF+FC+R+ ++KTVLMLADQMI+R+E++H+K+F Sbjct: 73 IPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNF 132 Query: 503 LHRDIKPDNFLMGLGKRANQVYMIDFGL 586 +HRDIKPDNFLMG+G+ N++++IDFGL Sbjct: 133 IHRDIKPDNFLMGIGRHCNKLFLIDFGL 160
>KC1A_RABIT (P67828) Casein kinase I isoform alpha (EC 2.7.11.1) (CKI-alpha)| (CK1) Length = 325 Score = 229 bits (583), Expect = 6e-60 Identities = 100/148 (67%), Positives = 132/148 (89%) Frame = +2 Query: 143 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 322 VG KY+L RK+GSGSFG+IYL N+ EEVA+KLE+ K +HPQLLYESKLY++LQGG G Sbjct: 13 VGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVG 72 Query: 323 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 502 I +++W+G E DYNVLVMD+LGPSLEDLF+FC+R+ ++KTVLMLADQMI+R+E++H+K+F Sbjct: 73 IPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNF 132 Query: 503 LHRDIKPDNFLMGLGKRANQVYMIDFGL 586 +HRDIKPDNFLMG+G+ N++++IDFGL Sbjct: 133 IHRDIKPDNFLMGIGRHCNKLFLIDFGL 160
>KC1A_BOVIN (P67827) Casein kinase I isoform alpha (EC 2.7.11.1) (CKI-alpha)| (CK1) Length = 325 Score = 229 bits (583), Expect = 6e-60 Identities = 100/148 (67%), Positives = 132/148 (89%) Frame = +2 Query: 143 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 322 VG KY+L RK+GSGSFG+IYL N+ EEVA+KLE+ K +HPQLLYESKLY++LQGG G Sbjct: 13 VGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVG 72 Query: 323 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 502 I +++W+G E DYNVLVMD+LGPSLEDLF+FC+R+ ++KTVLMLADQMI+R+E++H+K+F Sbjct: 73 IPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNF 132 Query: 503 LHRDIKPDNFLMGLGKRANQVYMIDFGL 586 +HRDIKPDNFLMG+G+ N++++IDFGL Sbjct: 133 IHRDIKPDNFLMGIGRHCNKLFLIDFGL 160
>KC1A_XENLA (P67963) Casein kinase I isoform alpha (EC 2.7.11.1) (CKI-alpha)| (CK1) Length = 337 Score = 229 bits (583), Expect = 6e-60 Identities = 100/148 (67%), Positives = 132/148 (89%) Frame = +2 Query: 143 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 322 VG KY+L RK+GSGSFG+IYL N+ EEVA+KLE+ K +HPQLLYESKLY++LQGG G Sbjct: 13 VGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVG 72 Query: 323 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 502 I +++W+G E DYNVLVMD+LGPSLEDLF+FC+R+ ++KTVLMLADQMI+R+E++H+K+F Sbjct: 73 IPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNF 132 Query: 503 LHRDIKPDNFLMGLGKRANQVYMIDFGL 586 +HRDIKPDNFLMG+G+ N++++IDFGL Sbjct: 133 IHRDIKPDNFLMGIGRHCNKLFLIDFGL 160
>KC1A_MOUSE (Q8BK63) Casein kinase I isoform alpha (EC 2.7.11.1) (CKI-alpha)| (CK1) Length = 337 Score = 229 bits (583), Expect = 6e-60 Identities = 100/148 (67%), Positives = 132/148 (89%) Frame = +2 Query: 143 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 322 VG KY+L RK+GSGSFG+IYL N+ EEVA+KLE+ K +HPQLLYESKLY++LQGG G Sbjct: 13 VGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVG 72 Query: 323 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 502 I +++W+G E DYNVLVMD+LGPSLEDLF+FC+R+ ++KTVLMLADQMI+R+E++H+K+F Sbjct: 73 IPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNF 132 Query: 503 LHRDIKPDNFLMGLGKRANQVYMIDFGL 586 +HRDIKPDNFLMG+G+ N++++IDFGL Sbjct: 133 IHRDIKPDNFLMGIGRHCNKLFLIDFGL 160
>KC1A_HUMAN (P48729) Casein kinase I isoform alpha (EC 2.7.11.1) (CKI-alpha)| (CK1) Length = 337 Score = 229 bits (583), Expect = 6e-60 Identities = 100/148 (67%), Positives = 132/148 (89%) Frame = +2 Query: 143 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 322 VG KY+L RK+GSGSFG+IYL N+ EEVA+KLE+ K +HPQLLYESKLY++LQGG G Sbjct: 13 VGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVG 72 Query: 323 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 502 I +++W+G E DYNVLVMD+LGPSLEDLF+FC+R+ ++KTVLMLADQMI+R+E++H+K+F Sbjct: 73 IPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNF 132 Query: 503 LHRDIKPDNFLMGLGKRANQVYMIDFGL 586 +HRDIKPDNFLMG+G+ N++++IDFGL Sbjct: 133 IHRDIKPDNFLMGIGRHCNKLFLIDFGL 160
>KC1A_CHICK (P67962) Casein kinase I isoform alpha (EC 2.7.11.1) (CKI-alpha)| (CK1) Length = 337 Score = 229 bits (583), Expect = 6e-60 Identities = 100/148 (67%), Positives = 132/148 (89%) Frame = +2 Query: 143 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 322 VG KY+L RK+GSGSFG+IYL N+ EEVA+KLE+ K +HPQLLYESKLY++LQGG G Sbjct: 13 VGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVG 72 Query: 323 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 502 I +++W+G E DYNVLVMD+LGPSLEDLF+FC+R+ ++KTVLMLADQMI+R+E++H+K+F Sbjct: 73 IPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNF 132 Query: 503 LHRDIKPDNFLMGLGKRANQVYMIDFGL 586 +HRDIKPDNFLMG+G+ N++++IDFGL Sbjct: 133 IHRDIKPDNFLMGIGRHCNKLFLIDFGL 160
>KC1A_RAT (P97633) Casein kinase I isoform alpha (EC 2.7.11.1) (CKI-alpha)| (CK1) Length = 325 Score = 226 bits (576), Expect = 4e-59 Identities = 99/148 (66%), Positives = 131/148 (88%) Frame = +2 Query: 143 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 322 VG KY+L RK+GSGSFG+IYL N+ EEVA+KLE+ K +HPQLLYESKLY++LQGG G Sbjct: 13 VGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVG 72 Query: 323 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 502 I +++W+G DYNVLVMD+LGPSLEDLF+FC+R+ ++KTVLMLADQMI+R+E++H+K+F Sbjct: 73 IPHIRWYGQGKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNF 132 Query: 503 LHRDIKPDNFLMGLGKRANQVYMIDFGL 586 +HRDIKPDNFLMG+G+ N++++IDFGL Sbjct: 133 IHRDIKPDNFLMGIGRHCNKLFLIDFGL 160
>KC1_PLAYO (Q7RBX5) Casein kinase I (EC 2.7.11.1)| Length = 323 Score = 224 bits (572), Expect = 1e-58 Identities = 99/152 (65%), Positives = 130/152 (85%) Frame = +2 Query: 131 MEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQ 310 ME RV NKY LG+KLGSGSFG+IY+ ++ T EE A+KLE+ ++KHPQLLYESKLY++L Sbjct: 1 MEIRVANKYALGKKLGSGSFGDIYVAKDIVTMEEFAVKLESTRSKHPQLLYESKLYKILG 60 Query: 311 GGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIH 490 GG G+ V W+G+EGD+ ++V+D+LGPSLEDLF+ CNRK SLKTVLM ADQM+NR+E++H Sbjct: 61 GGIGVPKVYWYGIEGDFTIMVLDLLGPSLEDLFTLCNRKFSLKTVLMTADQMLNRIEYVH 120 Query: 491 SKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 SK+F+HRDIKPDNFL+G GK+ +++IDFGL Sbjct: 121 SKNFIHRDIKPDNFLIGRGKKVTLIHIIDFGL 152
>KC1_PLAF7 (Q8IHZ9) Casein kinase I (EC 2.7.11.1)| Length = 323 Score = 224 bits (572), Expect = 1e-58 Identities = 99/152 (65%), Positives = 130/152 (85%) Frame = +2 Query: 131 MEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQ 310 ME RV NKY LG+KLGSGSFG+IY+ ++ T EE A+KLE+ ++KHPQLLYESKLY++L Sbjct: 1 MEIRVANKYALGKKLGSGSFGDIYVAKDIVTMEEFAVKLESTRSKHPQLLYESKLYKILG 60 Query: 311 GGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIH 490 GG G+ V W+G+EGD+ ++V+D+LGPSLEDLF+ CNRK SLKTVLM ADQM+NR+E++H Sbjct: 61 GGIGVPKVYWYGIEGDFTIMVLDLLGPSLEDLFTLCNRKFSLKTVLMTADQMLNRIEYVH 120 Query: 491 SKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 SK+F+HRDIKPDNFL+G GK+ +++IDFGL Sbjct: 121 SKNFIHRDIKPDNFLIGRGKKVTLIHIIDFGL 152
>KC1_PLAF4 (O15726) Casein kinase I (EC 2.7.11.1)| Length = 324 Score = 222 bits (566), Expect = 5e-58 Identities = 98/152 (64%), Positives = 129/152 (84%) Frame = +2 Query: 131 MEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQ 310 ME RV NKY LG+KLGSGSFG+IY+ ++ T EE A+KLE+ ++KHPQLLYESKLY++L Sbjct: 1 MEIRVANKYALGKKLGSGSFGDIYVAKDIVTMEEFAVKLESTRSKHPQLLYESKLYKILG 60 Query: 311 GGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIH 490 GG G+ V W+G+EGD+ ++V+D+LGPSLEDLF+ CNRK SLKTV M ADQM+NR+E++H Sbjct: 61 GGIGVPKVYWYGIEGDFTIMVLDLLGPSLEDLFTLCNRKFSLKTVRMTADQMLNRIEYVH 120 Query: 491 SKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 SK+F+HRDIKPDNFL+G GK+ +++IDFGL Sbjct: 121 SKNFIHRDIKPDNFLIGRGKKVTLIHIIDFGL 152
>YKL1_CAEEL (P42168) Putative casein kinase I C03C10.1 in chromosome III (EC| 2.7.11.1) Length = 341 Score = 222 bits (565), Expect = 7e-58 Identities = 98/148 (66%), Positives = 129/148 (87%) Frame = +2 Query: 143 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 322 V KY+L RK+GSGSFG+IY+ NV EEVAIKLE+ + +HPQLLYESK+YR+LQGG G Sbjct: 12 VATKYKLIRKIGSGSFGDIYVSINVTNGEEVAIKLESNRARHPQLLYESKVYRILQGGVG 71 Query: 323 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 502 I +++W+G E +YNVLVMD+LGPSLEDLF+FC+R+ ++KTVLMLADQMI R+E++H K+F Sbjct: 72 IPHIRWYGTEREYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMIGRIEYVHVKNF 131 Query: 503 LHRDIKPDNFLMGLGKRANQVYMIDFGL 586 +HRDIKPDNFLMG+G+ N++++IDFGL Sbjct: 132 IHRDIKPDNFLMGIGRHCNKLFLIDFGL 159
>KC1AL_HUMAN (Q8N752) Casein kinase I isoform alpha-like (EC 2.7.11.1)| (CKI-alpha-like) (CK1) Length = 337 Score = 221 bits (564), Expect = 9e-58 Identities = 100/148 (67%), Positives = 127/148 (85%) Frame = +2 Query: 143 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 322 VG KY+L RK+GSGSFG++YLG EEVA+KLE+ K KHPQLLYESKLY +LQGG G Sbjct: 13 VGGKYKLVRKIGSGSFGDVYLGITTTNGEEVAVKLESQKVKHPQLLYESKLYTILQGGVG 72 Query: 323 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 502 I ++ W+G E D NVLVMD+LGPSLEDLF+FC+R+ ++KTVLMLADQMI+R+E++H+K+F Sbjct: 73 IPHMHWYGQEKDNNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNF 132 Query: 503 LHRDIKPDNFLMGLGKRANQVYMIDFGL 586 LHRDIKPDNFLMG G+ N++++IDFGL Sbjct: 133 LHRDIKPDNFLMGTGRHCNKLFLIDFGL 160
>HRR25_YEAST (P29295) Casein kinase I homolog HRR25 (EC 2.7.11.1)| Length = 494 Score = 216 bits (549), Expect = 5e-56 Identities = 96/152 (63%), Positives = 131/152 (86%) Frame = +2 Query: 131 MEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQ 310 M+ RVG K+R+GRK+GSGSFG+IY GTN+ + EEVAIKLE+++++HPQL YES++YR L Sbjct: 1 MDLRVGRKFRIGRKIGSGSFGDIYHGTNLISGEEVAIKLESIRSRHPQLDYESRVYRYLS 60 Query: 311 GGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIH 490 GG GI ++WFG EG+YN +V+D+LGPSLEDLF++C+R+ S KTV+MLA QM R+++IH Sbjct: 61 GGVGIPFIRWFGREGEYNAMVIDLLGPSLEDLFNYCHRRFSFKTVIMLALQMFCRIQYIH 120 Query: 491 SKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 +SF+HRDIKPDNFLMG+G+R + V++IDFGL Sbjct: 121 GRSFIHRDIKPDNFLMGVGRRGSTVHVIDFGL 152
>KC1A_DROME (P54367) Casein kinase I isoform alpha (EC 2.7.11.1) (CKI-alpha)| (DmCK1) Length = 337 Score = 208 bits (530), Expect = 8e-54 Identities = 94/148 (63%), Positives = 122/148 (82%) Frame = +2 Query: 143 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 322 VG KYR+ RK+GSGSFG+IYLG ++Q+ EEVAIK+E+ +HPQLLYE+KLYR+L GG G Sbjct: 16 VGGKYRVIRKIGSGSFGDIYLGMSIQSGEEVAIKMESAHARHPQLLYEAKLYRILSGGVG 75 Query: 323 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 502 ++ G E ++N LVMD+LGPSLEDLF+FC R ++KTVLML DQMI R+E+IH K F Sbjct: 76 FPRIRHHGKEKNFNTLVMDLLGPSLEDLFNFCTRHFTIKTVLMLVDQMIGRLEYIHLKCF 135 Query: 503 LHRDIKPDNFLMGLGKRANQVYMIDFGL 586 +HRDIKPDNFLMG+G+ N++++IDFGL Sbjct: 136 IHRDIKPDNFLMGIGRHCNKLFLIDFGL 163
>HHP2_SCHPO (P40236) Casein kinase I homolog hhp2 (EC 2.7.11.1)| Length = 400 Score = 206 bits (524), Expect = 4e-53 Identities = 95/149 (63%), Positives = 121/149 (81%) Frame = +2 Query: 140 RVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGT 319 ++GNKYR+GRK+GSGSFG+IYLG N E+VA+KLE +K +H QL YE ++Y +L+G Sbjct: 7 KIGNKYRIGRKIGSGSFGQIYLGLNTVNGEQVAVKLEPLKARHHQLEYEFRVYNILKGNI 66 Query: 320 GISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKS 499 GI ++WFGV YN +VMD+LGPSLEDLF +C RK +LKTVL+LADQ+I+R+E++HSKS Sbjct: 67 GIPTIRWFGVTNSYNAMVMDLLGPSLEDLFCYCGRKFTLKTVLLLADQLISRIEYVHSKS 126 Query: 500 FLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 FLHRDIKPDNFLM K +N V MIDFGL Sbjct: 127 FLHRDIKPDNFLM--KKHSNVVTMIDFGL 153
>KC1B_BOVIN (P35507) Casein kinase I isoform beta (EC 2.7.11.1) (CKI-beta)| Length = 336 Score = 203 bits (517), Expect = 3e-52 Identities = 89/156 (57%), Positives = 127/156 (81%) Frame = +2 Query: 119 ARPPMEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLY 298 +RP + VG +Y+L R++G GSFG +YL ++ +E+VA+KLE+ T+ P+LL+E +LY Sbjct: 5 SRPKTDVLVGGRYKLVREIGFGSFGHVYLAIDLTNHEQVAVKLESENTRQPRLLHEKELY 64 Query: 299 RVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRV 478 LQGG GI ++W+G E DYNVLVMD+LGPSLEDLF+FC+R+ S+KTVLMLADQMI+R+ Sbjct: 65 NFLQGGVGIPQIRWYGQETDYNVLVMDLLGPSLEDLFNFCSRRFSMKTVLMLADQMISRI 124 Query: 479 EFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 E++HS++ +HRDIKPDNFLMG G + +++++DFGL Sbjct: 125 EYVHSRNLIHRDIKPDNFLMGTGPQWKKLFLVDFGL 160
>KC1A_PIG (O19175) Casein kinase I isoform alpha (EC 2.7.11.1) (CKI-alpha)| (CK1) (Fragment) Length = 125 Score = 193 bits (490), Expect = 4e-49 Identities = 83/120 (69%), Positives = 111/120 (92%) Frame = +2 Query: 227 EEVAIKLENVKTKHPQLLYESKLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDL 406 EEVA+KLE+ K +HPQLLYESKLY++LQGG GI +++W+G E DYNVLVMD+LGPSLEDL Sbjct: 2 EEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDL 61 Query: 407 FSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 F+FC+R+ ++KTVLMLADQMI+R+E++H+K+F+HRDIKPDNFLMG+G+ N++++IDFGL Sbjct: 62 FNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGL 121
>CKI2_SCHPO (P40234) Casein kinase I homolog 2 (EC 2.7.11.1)| Length = 435 Score = 167 bits (422), Expect = 3e-41 Identities = 82/150 (54%), Positives = 111/150 (74%), Gaps = 2/150 (1%) Frame = +2 Query: 143 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 322 VG YR+GRK+G GSFG I+ G N+ N+ +AIK E K++ PQL E + Y++L G G Sbjct: 8 VGVHYRVGRKIGEGSFGVIFDGMNLLNNQLIAIKFEPKKSEAPQLRDEYRTYKLLVGNAG 67 Query: 323 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 502 I NV +FG EG +N+LV+D+LGPSLEDLF +C R+ S+KTV M A QM++RV+ IH K+ Sbjct: 68 IPNVYYFGQEGLHNILVIDLLGPSLEDLFEWCGRRFSVKTVAMTAKQMLSRVQTIHEKNL 127 Query: 503 LHRDIKPDNFLMG--LGKRANQVYMIDFGL 586 ++RDIKPDNFL+G + AN VYM+DFG+ Sbjct: 128 VYRDIKPDNFLIGRPSSRNANMVYMVDFGM 157
>KC1G3_RAT (Q62763) Casein kinase I isoform gamma-3 (EC 2.7.11.1) (CKI-gamma| 3) Length = 448 Score = 166 bits (420), Expect = 5e-41 Identities = 82/150 (54%), Positives = 115/150 (76%), Gaps = 2/150 (1%) Frame = +2 Query: 143 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 322 VG +R+G+K+G G+FGE+ LG N+ TNE VAIKLE +K++ PQL E + Y+ L G G Sbjct: 39 VGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDG 98 Query: 323 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 502 I V +FG G YN +V+++LGPSLEDLF C+R SLKTVLM+A Q+I+R+E++HSK+ Sbjct: 99 IPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNL 158 Query: 503 LHRDIKPDNFLMGL-GKRANQV-YMIDFGL 586 ++RD+KP+NFL+G G +A QV ++IDFGL Sbjct: 159 IYRDVKPENFLIGRPGNKAQQVIHIIDFGL 188
>CKI1_SCHPO (P40233) Casein kinase I homolog 1 (EC 2.7.11.1)| Length = 446 Score = 166 bits (420), Expect = 5e-41 Identities = 82/150 (54%), Positives = 110/150 (73%), Gaps = 2/150 (1%) Frame = +2 Query: 143 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 322 VG Y++GR++G GSFG I+ GTN+ N++VAIK E ++ PQL E + Y++L G TG Sbjct: 8 VGVHYKVGRRIGEGSFGVIFEGTNLLNNQQVAIKFEPRRSDAPQLRDEYRTYKLLAGCTG 67 Query: 323 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 502 I NV +FG EG +N+LV+D+LGPSLEDL C RK S+KTV M A QM+ RV+ IH KS Sbjct: 68 IPNVYYFGQEGLHNILVIDLLGPSLEDLLDLCGRKFSVKTVAMAAKQMLARVQSIHEKSL 127 Query: 503 LHRDIKPDNFLMGL--GKRANQVYMIDFGL 586 ++RDIKPDNFL+G K AN +Y++DFG+ Sbjct: 128 VYRDIKPDNFLIGRPNSKNANMIYVVDFGM 157
>KC1G3_BOVIN (P35509) Casein kinase I isoform gamma-3 (EC 2.7.11.1) (CKI-gamma| 3) (Fragment) Length = 276 Score = 164 bits (416), Expect = 1e-40 Identities = 81/150 (54%), Positives = 114/150 (76%), Gaps = 2/150 (1%) Frame = +2 Query: 143 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 322 VG +R+G+K+G G+FGE+ LG N+ TNE VAIKLE +K++ PQL E + Y+ L G G Sbjct: 25 VGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDG 84 Query: 323 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 502 I V +FG G YN +V+++LGPSLEDLF C+R SLKTVLM+A Q+I+R+E++HSK+ Sbjct: 85 IPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNL 144 Query: 503 LHRDIKPDNFLMGL-GKRANQV-YMIDFGL 586 ++RD+KP+NFL+G G + QV ++IDFGL Sbjct: 145 IYRDVKPENFLIGRPGNKTQQVIHIIDFGL 174
>KC1G3_HUMAN (Q9Y6M4) Casein kinase I isoform gamma-3 (EC 2.7.11.1) (CKI-gamma| 3) Length = 447 Score = 164 bits (416), Expect = 1e-40 Identities = 81/150 (54%), Positives = 114/150 (76%), Gaps = 2/150 (1%) Frame = +2 Query: 143 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 322 VG +R+G+K+G G+FGE+ LG N+ TNE VAIKLE +K++ PQL E + Y+ L G G Sbjct: 39 VGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDG 98 Query: 323 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 502 I V +FG G YN +V+++LGPSLEDLF C+R SLKTVLM+A Q+I+R+E++HSK+ Sbjct: 99 IPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNL 158 Query: 503 LHRDIKPDNFLMGL-GKRANQV-YMIDFGL 586 ++RD+KP+NFL+G G + QV ++IDFGL Sbjct: 159 IYRDVKPENFLIGRPGNKTQQVIHIIDFGL 188
>KC1G2_RAT (Q62762) Casein kinase I isoform gamma-2 (EC 2.7.11.1) (CKI-gamma| 2) Length = 415 Score = 163 bits (412), Expect = 4e-40 Identities = 77/150 (51%), Positives = 112/150 (74%), Gaps = 2/150 (1%) Frame = +2 Query: 143 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 322 VG +R+G+K+G G+FGE+ LG N+ TNE VAIKLE +K++ PQL E + Y+ L G Sbjct: 42 VGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSTTEG 101 Query: 323 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 502 + V +FG G YN +V+++LGPSLEDLF C+R +LKTVLM+A Q+I R+E++H+KS Sbjct: 102 VPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSL 161 Query: 503 LHRDIKPDNFLMGL--GKRANQVYMIDFGL 586 ++RD+KP+NFL+G KR + +++IDFGL Sbjct: 162 IYRDVKPENFLVGRPGSKRQHSIHIIDFGL 191
>KC1G2_MOUSE (Q8BVP5) Casein kinase I isoform gamma-2 (EC 2.7.11.1) (CKI-gamma| 2) Length = 415 Score = 163 bits (412), Expect = 4e-40 Identities = 77/150 (51%), Positives = 112/150 (74%), Gaps = 2/150 (1%) Frame = +2 Query: 143 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 322 VG +R+G+K+G G+FGE+ LG N+ TNE VAIKLE +K++ PQL E + Y+ L G Sbjct: 42 VGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSTTEG 101 Query: 323 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 502 + V +FG G YN +V+++LGPSLEDLF C+R +LKTVLM+A Q+I R+E++H+KS Sbjct: 102 VPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSL 161 Query: 503 LHRDIKPDNFLMGL--GKRANQVYMIDFGL 586 ++RD+KP+NFL+G KR + +++IDFGL Sbjct: 162 IYRDVKPENFLVGRPGSKRQHSIHIIDFGL 191
>KC1G2_HUMAN (P78368) Casein kinase I isoform gamma-2 (EC 2.7.11.1) (CKI-gamma| 2) Length = 415 Score = 162 bits (411), Expect = 5e-40 Identities = 77/150 (51%), Positives = 112/150 (74%), Gaps = 2/150 (1%) Frame = +2 Query: 143 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 322 VG +R+G+K+G G+FGE+ LG N+ TNE VAIKLE +K++ PQL E + Y+ L G Sbjct: 42 VGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSATEG 101 Query: 323 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 502 + V +FG G YN +V+++LGPSLEDLF C+R +LKTVLM+A Q+I R+E++H+KS Sbjct: 102 VPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSL 161 Query: 503 LHRDIKPDNFLMGL--GKRANQVYMIDFGL 586 ++RD+KP+NFL+G KR + +++IDFGL Sbjct: 162 IYRDVKPENFLVGRPGTKRQHAIHIIDFGL 191
>CKI3_SCHPO (O74135) Casein kinase I homolog 3 (EC 2.7.11.1)| Length = 439 Score = 160 bits (405), Expect = 3e-39 Identities = 76/150 (50%), Positives = 108/150 (72%), Gaps = 2/150 (1%) Frame = +2 Query: 143 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 322 VG YR+G+K+G GSFG ++ G N+ N+ +A+K E+ K++ PQL E Y++L G G Sbjct: 11 VGVHYRVGKKIGEGSFGMLFQGVNLINNQPIALKFESRKSEVPQLRDEYLTYKLLMGLPG 70 Query: 323 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 502 I +V ++G EG YN+LVMD+LGPSLEDLF +C R+ S KTV M+A QMI R++ +H + F Sbjct: 71 IPSVYYYGQEGMYNLLVMDLLGPSLEDLFDYCGRRFSPKTVAMIAKQMITRIQSVHERHF 130 Query: 503 LHRDIKPDNFLMGL--GKRANQVYMIDFGL 586 ++RDIKPDNFL+G K N +Y +DFG+ Sbjct: 131 IYRDIKPDNFLIGFPGSKTENVIYAVDFGM 160
>KC1G1_MOUSE (Q8BTH8) Casein kinase I isoform gamma-1 (EC 2.7.11.1) (CKI-gamma| 1) Length = 459 Score = 159 bits (403), Expect = 4e-39 Identities = 76/151 (50%), Positives = 114/151 (75%), Gaps = 3/151 (1%) Frame = +2 Query: 143 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVL-QGGT 319 VG +R+G+K+G G+FGE+ LG N+ TNE VAIKLE +K++ PQL E + Y+ L G Sbjct: 40 VGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAGE 99 Query: 320 GISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKS 499 G+ V +FG G YN +V+++LGPSLEDLF C+R +LKTVLM+A Q+++R+E++HSK+ Sbjct: 100 GLPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKN 159 Query: 500 FLHRDIKPDNFLMGL--GKRANQVYMIDFGL 586 ++RD+KP+NFL+G K+ + +++IDFGL Sbjct: 160 LIYRDVKPENFLIGRQGNKKEHVIHIIDFGL 190
>KC1G1_RAT (Q62761) Casein kinase I isoform gamma-1 (EC 2.7.11.1) (CKI-gamma| 1) Length = 390 Score = 159 bits (403), Expect = 4e-39 Identities = 76/151 (50%), Positives = 114/151 (75%), Gaps = 3/151 (1%) Frame = +2 Query: 143 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVL-QGGT 319 VG +R+G+K+G G+FGE+ LG N+ TNE VAIKLE +K++ PQL E + Y+ L G Sbjct: 40 VGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAGE 99 Query: 320 GISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKS 499 G+ V +FG G YN +V+++LGPSLEDLF C+R +LKTVLM+A Q+++R+E++HSK+ Sbjct: 100 GLPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKN 159 Query: 500 FLHRDIKPDNFLMGL--GKRANQVYMIDFGL 586 ++RD+KP+NFL+G K+ + +++IDFGL Sbjct: 160 LIYRDVKPENFLIGRQGNKKEHVIHIIDFGL 190
>KC1G1_HUMAN (Q9HCP0) Casein kinase I isoform gamma-1 (EC 2.7.11.1) (CKI-gamma| 1) Length = 422 Score = 159 bits (403), Expect = 4e-39 Identities = 76/151 (50%), Positives = 114/151 (75%), Gaps = 3/151 (1%) Frame = +2 Query: 143 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVL-QGGT 319 VG +R+G+K+G G+FGE+ LG N+ TNE VAIKLE +K++ PQL E + Y+ L G Sbjct: 40 VGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAGE 99 Query: 320 GISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKS 499 G+ V +FG G YN +V+++LGPSLEDLF C+R +LKTVLM+A Q+++R+E++HSK+ Sbjct: 100 GLPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKN 159 Query: 500 FLHRDIKPDNFLMGL--GKRANQVYMIDFGL 586 ++RD+KP+NFL+G K+ + +++IDFGL Sbjct: 160 LIYRDVKPENFLIGRQGNKKEHVIHIIDFGL 190
>RAG8_KLULA (P40230) Casein kinase I homolog RAG8 (EC 2.7.11.1)| Length = 536 Score = 151 bits (382), Expect = 1e-36 Identities = 75/150 (50%), Positives = 104/150 (69%), Gaps = 2/150 (1%) Frame = +2 Query: 143 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 322 VG Y++G+K+G GSFG ++ G N+ N VAIK E KT PQL E + Y++L G G Sbjct: 73 VGLHYKIGKKIGEGSFGVLFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEG 132 Query: 323 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 502 I +FG EG +N+LV+D+LGPSLEDLF +C R+ S+KTV+ +A QMI +E +H Sbjct: 133 IPQAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHDL 192 Query: 503 LHRDIKPDNFLMGLGKR--ANQVYMIDFGL 586 ++RDIKPDNFL+G + AN V++IDFG+ Sbjct: 193 IYRDIKPDNFLIGRPNQPDANMVHLIDFGM 222
>KC12_YEAST (P23292) Casein kinase I homolog 2 (EC 2.7.11.1)| Length = 546 Score = 150 bits (378), Expect = 3e-36 Identities = 75/150 (50%), Positives = 107/150 (71%), Gaps = 2/150 (1%) Frame = +2 Query: 143 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 322 VG Y++G+K+G GSFG ++ GTN+ VAIK E KT+ PQL E + Y++L G G Sbjct: 72 VGLHYKIGKKIGEGSFGVLFEGTNMINGLPVAIKFEPRKTEAPQLKDEYRTYKILAGTPG 131 Query: 323 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 502 I +FG EG +N+LV+D+LGPSLEDLF +C R+ S+KTV+ +A QMI +E +H+ Sbjct: 132 IPQEYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSVKTVVQVAVQMITLIEDLHAHDL 191 Query: 503 LHRDIKPDNFLMGLGKR--ANQVYMIDFGL 586 ++RDIKPDNFL+G + AN+V++IDFG+ Sbjct: 192 IYRDIKPDNFLIGRPGQPDANKVHLIDFGM 221
>KC11_YEAST (P23291) Casein kinase I homolog 1 (EC 2.7.11.1)| Length = 538 Score = 150 bits (378), Expect = 3e-36 Identities = 75/150 (50%), Positives = 105/150 (70%), Gaps = 2/150 (1%) Frame = +2 Query: 143 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 322 VG Y++G+K+G GSFG ++ GTN+ VAIK E KT+ PQL E K Y++L G Sbjct: 65 VGLHYKIGKKIGEGSFGVLFEGTNMINGVPVAIKFEPRKTEAPQLRDEYKTYKILNGTPN 124 Query: 323 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 502 I +FG EG +N+LV+D+LGPSLEDLF +C RK S+KTV+ +A QMI +E +H+ Sbjct: 125 IPYAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRKFSVKTVVQVAVQMITLIEDLHAHDL 184 Query: 503 LHRDIKPDNFLMGLGKR--ANQVYMIDFGL 586 ++RDIKPDNFL+G + AN +++IDFG+ Sbjct: 185 IYRDIKPDNFLIGRPGQPDANNIHLIDFGM 214
>KC13_YEAST (P39962) Casein kinase I homolog 3 (EC 2.7.11.1)| Length = 524 Score = 137 bits (344), Expect = 3e-32 Identities = 77/183 (42%), Positives = 102/183 (55%), Gaps = 35/183 (19%) Frame = +2 Query: 143 VGNKYRLGRKLGSGSFGEIYLGTNV-----------------QTNEEVAIKLENVKTKHP 271 VG Y +G K+G GSFG I+ G N+ NE VAIK E + P Sbjct: 10 VGIHYAVGPKIGEGSFGVIFEGENILHSCQAQTGSKRDSSIIMANEPVAIKFEPRHSDAP 69 Query: 272 QLLYESKLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLM 451 QL E + YR+L G GI + +FG EG +N+L++D+LGPSLEDLF +C RK S+KT M Sbjct: 70 QLRDEFRAYRILNGCVGIPHAYYFGQEGMHNILIIDLLGPSLEDLFEWCGRKFSVKTTCM 129 Query: 452 LADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKR------------------ANQVYMID 577 +A QMI+RV IH ++RDIKPDNFL+ +R N +YM+D Sbjct: 130 VAKQMIDRVRAIHDHDLIYRDIKPDNFLISQYQRISPEGKVIKSCASSSNNDPNLIYMVD 189 Query: 578 FGL 586 FG+ Sbjct: 190 FGM 192
>TTBK1_HUMAN (Q5TCY1) Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau| kinase) Length = 1321 Score = 96.3 bits (238), Expect = 6e-20 Identities = 62/167 (37%), Positives = 89/167 (53%), Gaps = 2/167 (1%) Frame = +2 Query: 92 GGGSVACVRARPPMEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHP 271 GGG A + P V +++++ +K+G G FGEIY ++ T E VA+K+E+ + Sbjct: 16 GGGEQADIL---PANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQ 72 Query: 272 QLLYESKLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNR-KLSLKTVL 448 L E + + LQG + G +N +VM + G +L DL R +L T L Sbjct: 73 VLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTL 132 Query: 449 MLADQMINRVEFIHSKSFLHRDIKPDNFLMG-LGKRANQVYMIDFGL 586 L Q++ +E IHS FLHRDIKP NF MG L + YM+DFGL Sbjct: 133 RLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGL 179
>TTBK2_HUMAN (Q6IQ55) Tau-tubulin kinase 2 (EC 2.7.11.1)| Length = 1244 Score = 94.4 bits (233), Expect = 2e-19 Identities = 56/150 (37%), Positives = 82/150 (54%), Gaps = 2/150 (1%) Frame = +2 Query: 143 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 322 V ++++ RK+G G FGEIY ++ T E VA+K+E+ + L E + + LQG Sbjct: 17 VKERWKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDH 76 Query: 323 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNR-KLSLKTVLMLADQMINRVEFIHSKS 499 + G +N +VM + G +L DL +R ++ T L L Q++ +E IHS Sbjct: 77 VCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVG 136 Query: 500 FLHRDIKPDNFLMG-LGKRANQVYMIDFGL 586 FLHRDIKP NF MG + YM+DFGL Sbjct: 137 FLHRDIKPSNFAMGRFPSTCRKCYMLDFGL 166
>TTBK2_MOUSE (Q3UVR3) Tau-tubulin kinase 2| Length = 1243 Score = 93.2 bits (230), Expect = 5e-19 Identities = 55/150 (36%), Positives = 82/150 (54%), Gaps = 2/150 (1%) Frame = +2 Query: 143 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 322 V ++++ RK+G G FGEIY ++ T E VA+K+E+ + L E + + LQG Sbjct: 17 VKERWKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDH 76 Query: 323 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNR-KLSLKTVLMLADQMINRVEFIHSKS 499 + G +N +VM + G +L DL +R ++ T L L Q++ +E IHS Sbjct: 77 VCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGKQILESIESIHSVG 136 Query: 500 FLHRDIKPDNFLMG-LGKRANQVYMIDFGL 586 FLHRDIKP NF MG + +M+DFGL Sbjct: 137 FLHRDIKPSNFAMGRFPSTCRKCFMLDFGL 166
>YKL2_CAEEL (P42169) Putative casein kinase I C03C10.2 in chromosome III (EC| 2.7.11.1) Length = 363 Score = 75.1 bits (183), Expect = 1e-13 Identities = 47/156 (30%), Positives = 89/156 (57%), Gaps = 10/156 (6%) Frame = +2 Query: 149 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLE-----NVKTKHPQLLYESKLYRVLQG 313 N++ + +G+G +G+I++ +V+ N+E A+K+E V TK +++ E ++ +QG Sbjct: 70 NRWSIEGVIGNGGYGQIFMVMDVKKNDERAMKIEPKLRAEVITK--RMIMEQQVLMKMQG 127 Query: 314 GTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNR----KLSLKTVLMLADQMINRVE 481 T I + G +N ++M +L ++ D F R +LS +TV +A Q +N ++ Sbjct: 128 KTHIPTMYASGFNDQFNFIIMQLLSMNVGD---FRKRSPLGRLSKETVGRIAYQTLNALK 184 Query: 482 FIHSKSFLHRDIKPDNFLMGL-GKRANQVYMIDFGL 586 IH ++HRD+KP N G+ + + +Y++DFGL Sbjct: 185 DIHDMGYVHRDVKPANICFGVHAQNRHILYLLDFGL 220
>PKN2_MYXXA (P54736) Serine/threonine-protein kinase pkn2 (EC 2.7.11.1)| Length = 830 Score = 69.7 bits (169), Expect = 6e-12 Identities = 50/152 (32%), Positives = 76/152 (50%), Gaps = 7/152 (4%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQ------LLYESKLYRVLQG 313 ++R+ R LGSG GE+YLG V +VAIK+ + H Q E++L ++ Sbjct: 12 RFRVLRPLGSGGMGEVYLGEQVSLGRKVAIKVLH-HDLHAQAGMAERFKREARLLSAVEH 70 Query: 314 GTGISNVKWFGVEGDYNVLVMD-VLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIH 490 + V FG GD+ LVM+ V G SL D+ + + L L Q+ + IH Sbjct: 71 PAVVRIVD-FGESGDHACLVMEFVEGESLYDVLT--PGPMPPGRALPLLQQLAEGLAAIH 127 Query: 491 SKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 K +HRD+KP+N + R Q ++DFG+ Sbjct: 128 DKGIIHRDLKPENVFISKSARGEQARLLDFGI 159
>VRK2_HUMAN (Q86Y07) Serine/threonine-protein kinase VRK2 (EC 2.7.11.1)| (Vaccinia-related kinase 2) Length = 508 Score = 68.2 bits (165), Expect = 2e-11 Identities = 54/170 (31%), Positives = 82/170 (48%), Gaps = 23/170 (13%) Frame = +2 Query: 146 GNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVK-TKHPQLLYESKLYR------- 301 GN++ LG+K+GSG FG IYL E+ A + V+ ++ L E K Y+ Sbjct: 26 GNQWVLGKKIGSGGFGLIYLAFPTNKPEKDARHVVKVEYQENGPLFSELKFYQRVAKKDC 85 Query: 302 ---------------VLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSL 436 L G+G++ K Y +VM+ LG L+ + S N Sbjct: 86 IKKWIERKQLDYLGIPLFYGSGLTEFKG----RSYRFMVMERLGIDLQKI-SGQNGTFKK 140 Query: 437 KTVLMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 TVL L +M++ +E+IH ++H DIK N L+G K +QVY+ D+GL Sbjct: 141 STVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLGY-KNPDQVYLADYGL 189
>PAK1_CAEEL (Q17850) Serine/threonine-protein kinase pak-1 (EC 2.7.11.1)| (p21-activated kinase 1) (PAK1) (CePAK) Length = 572 Score = 67.8 bits (164), Expect = 2e-11 Identities = 46/152 (30%), Positives = 80/152 (52%), Gaps = 5/152 (3%) Frame = +2 Query: 143 VGN---KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKT--KHPQLLYESKLYRVL 307 +GN KYR K+GSG+ G +Y + T EVAIK N+K K ++ E + R Sbjct: 288 IGNPDRKYRKVDKIGSGASGSVYTAIEISTEAEVAIKQMNLKDQPKKELIINEILVMREN 347 Query: 308 QGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFI 487 + ++ + + V + V++ + G SL D+ + C + + + + +++ +EF+ Sbjct: 348 KHANIVNYLDSYLVCDELWVVMEYLAGGSLTDVVTECQMEDGI--IAAVCREVLQALEFL 405 Query: 488 HSKSFLHRDIKPDNFLMGLGKRANQVYMIDFG 583 HS+ +HRDIK DN L+G+ V + DFG Sbjct: 406 HSRHVIHRDIKSDNILLGMD---GSVKLTDFG 434
>PIM1_BRARE (Q9YHZ5) Serine/threonine-protein kinase Pim-1 (EC 2.7.11.1)| Length = 310 Score = 67.4 bits (163), Expect = 3e-11 Identities = 52/163 (31%), Positives = 79/163 (48%), Gaps = 19/163 (11%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK---LENVK--TKHP----QLLYESKLYRV 304 +Y +G LGSG FG +Y G + ++VAIK + ++ +K P + E L + Sbjct: 29 QYTMGNLLGSGGFGSVYSGHRISDGQKVAIKQISRDRIQQWSKMPGEVNPVPNEIALLQS 88 Query: 305 LQGGTG--------ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVL--ML 454 L GG+G I + WF + G ++V + +DLF F + L L Sbjct: 89 LGGGSGSVPGHRGIIRMLDWFEIPGQEYLIVFE-KPQHCQDLFDFITERGRLDESLARRF 147 Query: 455 ADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFG 583 Q+I V+F HSK +HRDIK +N L + R + +IDFG Sbjct: 148 LKQVIEAVQFCHSKGIVHRDIKDENIL--VDTRTGDIKVIDFG 188
>VRK1_MOUSE (Q80X41) Serine/threonine-protein kinase VRK1 (EC 2.7.11.1)| (Vaccinia-related kinase 1) (Serine/threonine-protein kinase 51PK) Length = 440 Score = 67.0 bits (162), Expect = 4e-11 Identities = 49/168 (29%), Positives = 84/168 (50%), Gaps = 23/168 (13%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLG-TN----VQTNEEVAIKLENVKTKHPQLLYESKLYR----- 301 +++LG +G G FG IYL TN V ++ +K+E + + L E K Y+ Sbjct: 36 EWKLGLPIGQGGFGCIYLADTNSSKPVGSDAPCVVKVE--PSDNGPLFTELKFYQRAAKP 93 Query: 302 -VLQGGTGISNVKWFGVEG------------DYNVLVMDVLGPSLEDLFSFCNRKLSLKT 442 +Q +K+ GV Y ++MD G L+ ++ ++ S KT Sbjct: 94 EQIQKWIRTHKLKYLGVPKYWGSGLHDKNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKT 153 Query: 443 VLMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 VL L+ ++++ +E+IH ++H DIK N L+ K +QVY++D+GL Sbjct: 154 VLQLSLRILDILEYIHEHEYVHGDIKASNLLLS-HKNPDQVYLVDYGL 200
>VRK1_HUMAN (Q99986) Serine/threonine-protein kinase VRK1 (EC 2.7.11.1)| (Vaccinia-related kinase 1) Length = 396 Score = 66.6 bits (161), Expect = 5e-11 Identities = 47/167 (28%), Positives = 81/167 (48%), Gaps = 22/167 (13%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQ----LLYESKLYR------ 301 ++++G +G G FG IYL ++ ++E V V P L E K Y+ Sbjct: 36 EWKVGLPIGQGGFGCIYLA-DMNSSESVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPE 94 Query: 302 VLQGGTGISNVKWFGVEG------------DYNVLVMDVLGPSLEDLFSFCNRKLSLKTV 445 +Q +K+ GV Y ++MD G L+ ++ ++ S KTV Sbjct: 95 QIQKWIRTRKLKYLGVPKYWGSGLHDKNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTV 154 Query: 446 LMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 L L+ ++++ +E+IH ++H DIK N L+ K +QVY++D+GL Sbjct: 155 LQLSLRILDILEYIHEHEYVHGDIKASNLLLNY-KNPDQVYLVDYGL 200
>KCC2_YEAST (P22517) Calcium/calmodulin-dependent protein kinase II (EC| 2.7.11.17) Length = 447 Score = 66.2 bits (160), Expect = 7e-11 Identities = 45/150 (30%), Positives = 74/150 (49%), Gaps = 6/150 (4%) Frame = +2 Query: 155 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHP-----QLLYES-KLYRVLQGG 316 Y GR LG+GSFG + + TNE+VAIK+ K Q+LYE + + L Sbjct: 47 YIFGRTLGAGSFGVVRQARKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLSHP 106 Query: 317 TGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSK 496 +S WF + + ++ G L D + + V ++ Q++ VE++HSK Sbjct: 107 NIVSFKDWFESKDKFYIVTQLATGGELFDRILSRGKFTEVDAVEIIV-QILGAVEYMHSK 165 Query: 497 SFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 + +HRD+KP+N L + + + DFG+ Sbjct: 166 NVVHRDLKPENVLYVDKSENSPLVIADFGI 195
>V212_FOWPV (Q9J523) Probable serine/threonine-protein kinase FPV212 (EC| 2.7.11.1) Length = 303 Score = 65.9 bits (159), Expect = 8e-11 Identities = 52/171 (30%), Positives = 85/171 (49%), Gaps = 19/171 (11%) Frame = +2 Query: 131 MEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLY-RVL 307 +E NK+ LG++LGSG FG +Y + + K+E ++ L E Y RV+ Sbjct: 17 LEDITKNKWILGKQLGSGGFGLVYQVSCKSKEIDCVAKIELKESGG--LFCEINFYNRVM 74 Query: 308 QGGT--------------GISNVKWFGV----EGDYNVLVMDVLGPSLEDLFSFCNRKLS 433 + T GI + FG+ +Y ++ LG LE++ S K + Sbjct: 75 KNKTSLDTWMKEQKIDYIGIPSFHGFGITIYKNVEYRFAIIQRLGRDLENILSE-KEKFN 133 Query: 434 LKTVLMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 + + LA ++++ ++FIHSK F H DIK N L GK ++VY++D+GL Sbjct: 134 ITVIKKLAIKILDILKFIHSKEFSHGDIKAGNIL--FGKDDDKVYLVDYGL 182
>VRK1_BRARE (Q7ZUS1) Serine/threonine-protein kinase VRK1 (EC 2.7.11.1)| (Vaccinia-related kinase 1) Length = 425 Score = 65.1 bits (157), Expect = 1e-10 Identities = 48/168 (28%), Positives = 77/168 (45%), Gaps = 23/168 (13%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLGTN-----VQTNEEVAIKLENVKTKHPQLLYESKLYR----- 301 K++LG +G G FG +YL V + IK+E + + L E K Y Sbjct: 37 KWKLGSAVGQGGFGLLYLANEDSSGPVTADAPYVIKVE--PSDNGPLFSELKFYMRAAKP 94 Query: 302 -VLQGGTGISNVKWFGVEG------------DYNVLVMDVLGPSLEDLFSFCNRKLSLKT 442 ++ +++ GV Y +VMD G L+ LF +K S K Sbjct: 95 DLIGAWMKSKKMEYLGVPKYWGSGFHEKNGKRYRFMVMDRFGTDLQKLFEGNGKKFSRKL 154 Query: 443 VLMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 VL L ++++ +E+IH ++H DIK N L+ NQV+++D+GL Sbjct: 155 VLQLGLRLLDILEYIHDHEYVHADIKASNLLLSY-TNPNQVFLVDYGL 201
>MARK4_MOUSE (Q8CIP4) MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1)| Length = 752 Score = 64.7 bits (156), Expect = 2e-10 Identities = 51/171 (29%), Positives = 88/171 (51%), Gaps = 5/171 (2%) Frame = +2 Query: 86 NLGGGSVACVRARPPMEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTK 265 +LG + + P +P VGN YRL R +G G+F ++ L ++ T EVAIK+ + Sbjct: 37 SLGARCRNSIASCPEEQPHVGN-YRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQL 95 Query: 266 HPQLLYESKLYRVLQGGTGISN---VKWFGVEGDYNVLVMDVLGPSLEDLFSF--CNRKL 430 +P L KL+R ++ G+++ VK F V L + + S ++F + + ++ Sbjct: 96 NPSSL--QKLFREVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRM 153 Query: 431 SLKTVLMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFG 583 K Q+++ V + H K+ +HRD+K +N L L AN + + DFG Sbjct: 154 KEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLL--LDAEAN-IKIADFG 201
>MARK4_HUMAN (Q96L34) MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase-like 1) Length = 752 Score = 64.7 bits (156), Expect = 2e-10 Identities = 51/171 (29%), Positives = 88/171 (51%), Gaps = 5/171 (2%) Frame = +2 Query: 86 NLGGGSVACVRARPPMEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTK 265 +LG + + P +P VGN YRL R +G G+F ++ L ++ T EVAIK+ + Sbjct: 37 SLGARCRNSIASCPEEQPHVGN-YRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQL 95 Query: 266 HPQLLYESKLYRVLQGGTGISN---VKWFGVEGDYNVLVMDVLGPSLEDLFSF--CNRKL 430 +P L KL+R ++ G+++ VK F V L + + S ++F + + ++ Sbjct: 96 NPSSL--QKLFREVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRM 153 Query: 431 SLKTVLMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFG 583 K Q+++ V + H K+ +HRD+K +N L L AN + + DFG Sbjct: 154 KEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLL--LDAEAN-IKIADFG 201
>CDC7_HUMAN (O00311) Cell division cycle 7-related protein kinase (EC 2.7.11.1)| (CDC7-related kinase) (HsCdc7) (huCdc7) Length = 574 Score = 63.5 bits (153), Expect = 4e-10 Identities = 45/154 (29%), Positives = 75/154 (48%), Gaps = 4/154 (2%) Frame = +2 Query: 137 PRVGNKYRLGRKLGSGSFGEIYLGT---NVQTNEEVAIKLENVKTKHP-QLLYESKLYRV 304 P++ N +++ K+G G+F +YL T V E++A+K + T HP ++ E + V Sbjct: 52 PQLSNVFKIEDKIGEGTFSSVYLATAQLQVGPEEKIALK-HLIPTSHPIRIAAELQCLTV 110 Query: 305 LQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEF 484 G + VK+ + D+ V+ M L E N LS + V + ++ Sbjct: 111 AGGQDNVMGVKYCFRKNDHVVIAMPYL--EHESFLDILN-SLSFQEVREYMLNLFKALKR 167 Query: 485 IHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 IH +HRD+KP NFL +R + ++DFGL Sbjct: 168 IHQFGIVHRDVKPSNFL--YNRRLKKYALVDFGL 199
>PKND_CHLTR (O84303) Serine/threonine-protein kinase pknD (EC 2.7.11.1)| Length = 934 Score = 62.8 bits (151), Expect = 7e-10 Identities = 50/166 (30%), Positives = 79/166 (47%), Gaps = 22/166 (13%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-----LENVKTKHPQLLYESKL------- 295 +Y L R +G G GE+YL + + VA+K L + L E+K+ Sbjct: 3 RYELIRLIGKGGMGEVYLAHDKACSRRVALKRIREDLSGNALLRQRFLREAKIAADLIHP 62 Query: 296 -----YRVLQGGTGI----SNVKWFGVEGDY-NVLVMDVLGPSLEDLFSFCNRKLSLKTV 445 Y + G + ++ F ++ +V +VL LE+ K S+K+ Sbjct: 63 GIVPVYSICSDGEAVYYTMPYIEGFSLKSLLKSVWQKEVLSKELEE-------KTSVKSF 115 Query: 446 LMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFG 583 L + D++ VE+IHSK LHRD+KPDN L+GL +V +ID+G Sbjct: 116 LPIFDKICATVEYIHSKGVLHRDLKPDNILLGL---FGEVVIIDWG 158
>CSK2A_DICDI (Q02720) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II alpha| subunit) Length = 337 Score = 62.4 bits (150), Expect = 9e-10 Identities = 43/146 (29%), Positives = 78/146 (53%), Gaps = 2/146 (1%) Frame = +2 Query: 155 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVLQGGTGISN 331 Y + RK+G G + E++ G N++ NE+ IK L+ VK K ++ E K+ + L GG I Sbjct: 47 YEIIRKIGRGKYSEVFEGANIKNNEKCVIKVLKPVKKK--KIKREIKILQNLCGGPNI-- 102 Query: 332 VKWFGVEGDYNVLVMDVLGPSLEDL-FSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLH 508 + + V D ++ + + F + L+ V ++++ ++F HS +H Sbjct: 103 ITLYDVVRDPQSKTPSLIFEYINNTDFKHLSPTLTDFDVRYYIRELLHALDFCHSNGIMH 162 Query: 509 RDIKPDNFLMGLGKRANQVYMIDFGL 586 RD+KP N ++ KR ++Y+ID+GL Sbjct: 163 RDVKPSNVMIDHQKR--KLYLIDWGL 186
>PKN1_MYXXA (P33973) Serine/threonine-protein kinase pkn1 (EC 2.7.11.1)| Length = 693 Score = 62.4 bits (150), Expect = 9e-10 Identities = 53/184 (28%), Positives = 91/184 (49%), Gaps = 11/184 (5%) Frame = +2 Query: 68 P*LDALNLGGGSVACVRARPPME---PRVG---NKYRLGRKLGSGSFGEIYLGTNVQTNE 229 P L ++ G A R P +E P VG +RL R+LG G G +YLG +V Sbjct: 24 PTLVRADVRAGGTAHPRCAPVVEAQDPLVGVRCGSFRLVRRLGRGGMGAVYLGEHVSIGS 83 Query: 230 EVAIKLENVK-TKHPQLL--YESKLYRV-LQGGTGISNVKWFGVEGDYNVLVMDVLGPSL 397 VA+K+ + T +P+L+ + ++ V L G I ++ L+M+ L + Sbjct: 84 RVAVKVLHAHLTMYPELVQRFHAEARAVNLIGHENIVSIFDMDATPPRPYLIMEFLDGA- 142 Query: 398 EDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRDIKPDN-FLMGLGKRANQVYMI 574 L ++ L+ V+ + Q+ + ++ H++ +HRD+KPDN FL+ A V ++ Sbjct: 143 -PLSAWVGTPLAAGAVVSVLSQVCDALQAAHARGIVHRDLKPDNIFLVRRNGNAPFVKVL 201 Query: 575 DFGL 586 DFG+ Sbjct: 202 DFGI 205
>SNF1_CANGA (Q00372) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 612 Score = 62.4 bits (150), Expect = 9e-10 Identities = 51/169 (30%), Positives = 81/169 (47%), Gaps = 20/169 (11%) Frame = +2 Query: 140 RVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKT------------------- 262 RVGN Y++ + LG GSFG++ L +V T ++VA+K+ N K Sbjct: 35 RVGN-YQIVKTLGEGSFGKVKLAYHVTTGQKVALKIINKKVLAKSDMQGRIEREISYLRL 93 Query: 263 -KHPQLLYESKLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLK 439 +HP ++ KLY V++ D ++V++ G L D + K+S + Sbjct: 94 LRHPHII---KLYDVIK-------------SKDEIIMVIEYAGNELFD-YIVQRNKMSEQ 136 Query: 440 TVLMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 Q+I+ VE+ H +HRD+KP+N L L + N V + DFGL Sbjct: 137 EARRFFQQIISAVEYCHRHKIVHRDLKPENLL--LDEHLN-VKIADFGL 182
>CSK2A_CAEEL (P18334) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II alpha| subunit) Length = 360 Score = 62.0 bits (149), Expect = 1e-09 Identities = 45/153 (29%), Positives = 79/153 (51%), Gaps = 9/153 (5%) Frame = +2 Query: 155 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVLQGGTGISN 331 Y+L RKLG G + E++ G + T+E+V +K L+ VK K ++ E K+ L+GGT I Sbjct: 38 YQLVRKLGRGKYSEVFEGFKMSTDEKVVVKILKPVKKK--KIKREIKILENLRGGTNIIT 95 Query: 332 VKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLAD--------QMINRVEFI 487 + +V D + + +F N + L+D +++ ++F Sbjct: 96 LL---------DVVKDPISRTPALIFEHVNNSDFKQLYQTLSDYDIRYYLYELLKALDFC 146 Query: 488 HSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 HS+ +HRD+KP N ++ KR ++ +ID+GL Sbjct: 147 HSQGIMHRDVKPHNVMIDAEKR--ELRLIDWGL 177
>YOO3_CAEEL (P34635) Putative serine/threonine-protein kinase ZK507.3 (EC| 2.7.11.1) Length = 374 Score = 61.6 bits (148), Expect = 2e-09 Identities = 30/83 (36%), Positives = 47/83 (56%), Gaps = 1/83 (1%) Frame = +2 Query: 341 FGVEGDYNVLVMDVLGPSLEDL-FSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRDI 517 FG + +VM ++GPSLE+L + + T+L Q + + H FLHRDI Sbjct: 100 FGQSPVWKWIVMTIVGPSLEELKMKYKPSDIPPSTILQCGLQTMKAIHDFHQIGFLHRDI 159 Query: 518 KPDNFLMGLGKRANQVYMIDFGL 586 KP N+ +G G ++ +Y++DFGL Sbjct: 160 KPANYCIGYGSKSETIYVLDFGL 182
>CSK22_MOUSE (O54833) Casein kinase II subunit alpha' (EC 2.7.11.1) (CK II)| Length = 350 Score = 61.6 bits (148), Expect = 2e-09 Identities = 47/161 (29%), Positives = 81/161 (50%), Gaps = 11/161 (6%) Frame = +2 Query: 137 PRVGNK--YRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVL 307 P GN+ Y+L RKLG G + E++ N+ NE V +K L+ VK K ++ E K+ L Sbjct: 32 PSWGNQDDYQLVRKLGRGKYSEVFEAINITNNERVVVKILKPVKKK--KIKREVKILENL 89 Query: 308 QGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLAD--------Q 463 +GGT I +K V D + + +F + N + +L D + Sbjct: 90 RGGTNI--IKLIDT-------VKDPVSKTPALVFEYINNTDFKQLYQILTDFDIRFYMYE 140 Query: 464 MINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 ++ +++ HSK +HRD+KP N + + + ++ +ID+GL Sbjct: 141 LLKALDYCHSKGIMHRDVKPHNVM--IDHQQKKLRLIDWGL 179
>CSK22_HUMAN (P19784) Casein kinase II subunit alpha' (EC 2.7.11.1) (CK II)| Length = 350 Score = 61.6 bits (148), Expect = 2e-09 Identities = 47/161 (29%), Positives = 81/161 (50%), Gaps = 11/161 (6%) Frame = +2 Query: 137 PRVGNK--YRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVL 307 P GN+ Y+L RKLG G + E++ N+ NE V +K L+ VK K ++ E K+ L Sbjct: 32 PSWGNQDDYQLVRKLGRGKYSEVFEAINITNNERVVVKILKPVKKK--KIKREVKILENL 89 Query: 308 QGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLAD--------Q 463 +GGT I +K V D + + +F + N + +L D + Sbjct: 90 RGGTNI--IKLIDT-------VKDPVSKTPALVFEYINNTDFKQLYQILTDFDIRFYMYE 140 Query: 464 MINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 ++ +++ HSK +HRD+KP N + + + ++ +ID+GL Sbjct: 141 LLKALDYCHSKGIMHRDVKPHNVM--IDHQQKKLRLIDWGL 179
>CSK22_BOVIN (P20427) Casein kinase II subunit alpha' (EC 2.7.11.1) (CK II)| Length = 350 Score = 61.6 bits (148), Expect = 2e-09 Identities = 47/161 (29%), Positives = 81/161 (50%), Gaps = 11/161 (6%) Frame = +2 Query: 137 PRVGNK--YRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVL 307 P GN+ Y+L RKLG G + E++ N+ NE V +K L+ VK K ++ E K+ L Sbjct: 32 PSWGNQDDYQLVRKLGRGKYSEVFEAINITNNERVVVKILKPVKKK--KIKREVKILENL 89 Query: 308 QGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLAD--------Q 463 +GGT I +K V D + + +F + N + +L D + Sbjct: 90 RGGTNI--IKLIDT-------VKDPVSKTPALVFEYINNTDFKQLYQILTDFDIRFYMYE 140 Query: 464 MINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 ++ +++ HSK +HRD+KP N + + + ++ +ID+GL Sbjct: 141 LLKALDYCHSKGIMHRDVKPHNVM--IDHQQKKLRLIDWGL 179
>YOO1_CAEEL (P34633) Putative serine/threonine-protein kinase ZK507.1 (EC| 2.7.11.1) Length = 331 Score = 61.6 bits (148), Expect = 2e-09 Identities = 30/83 (36%), Positives = 47/83 (56%), Gaps = 1/83 (1%) Frame = +2 Query: 341 FGVEGDYNVLVMDVLGPSLEDL-FSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRDI 517 FG + +VM ++GPSLE+L + + T+L Q + + H FLHRDI Sbjct: 58 FGQSPVWKWIVMTIVGPSLEELKMKYKPSDIPPSTILQCGLQTMKAIHDFHQIGFLHRDI 117 Query: 518 KPDNFLMGLGKRANQVYMIDFGL 586 KP N+ +G G ++ +Y++DFGL Sbjct: 118 KPANYCIGYGSKSETIYVLDFGL 140
>PKND_CHLMU (Q9PK92) Serine/threonine-protein kinase pknD (EC 2.7.11.1)| Length = 934 Score = 61.2 bits (147), Expect = 2e-09 Identities = 49/167 (29%), Positives = 78/167 (46%), Gaps = 23/167 (13%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-----LENVKTKHPQLLYESKL------- 295 +Y L R +G G GE+YL + + VA+K L + + L E+K+ Sbjct: 3 RYELIRLIGRGGMGEVYLAHDKACSRRVALKKIREDLSDNPLLRKRFLREAKIAADLIHP 62 Query: 296 -----YRVLQGGTGISNVKWFGVEGDY------NVLVMDVLGPSLEDLFSFCNRKLSLKT 442 Y + G + + +EG +V ++L LE+ K S+K Sbjct: 63 GIVPVYSICSDGESVYYTMPY-IEGFSLKHLLKSVWQKEILSKELEE-------KTSVKA 114 Query: 443 VLMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFG 583 L + D++ VE+IHSK LHRD+KPDN L+GL +V ++D+G Sbjct: 115 FLPIFDKICATVEYIHSKGVLHRDLKPDNILLGL---FGEVVIVDWG 158
>CSK22_CHICK (P21869) Casein kinase II subunit alpha' (EC 2.7.11.1) (CK II)| Length = 350 Score = 60.8 bits (146), Expect = 3e-09 Identities = 46/161 (28%), Positives = 80/161 (49%), Gaps = 11/161 (6%) Frame = +2 Query: 137 PRVGNK--YRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVL 307 P GN+ Y+L RKLG G + E++ N+ NE V +K L+ VK K ++ E K+ L Sbjct: 32 PSWGNQDDYQLVRKLGRGKYSEVFEAINITNNERVVVKILKPVKKK--KIKREVKILENL 89 Query: 308 QGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLAD--------Q 463 +GGT I N+ V D + + +F + N + +L D + Sbjct: 90 RGGTNIINL---------IDTVKDPVSKTPALVFEYINNTDFKQLYQILTDFDIRFYMYE 140 Query: 464 MINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 ++ +++ HS +HRD+KP N + + + ++ +ID+GL Sbjct: 141 LLKALDYCHSMGIMHRDVKPHNVM--IDHQQKKLRLIDWGL 179
>STE20_YEAST (Q03497) Serine/threonine-protein kinase STE20 (EC 2.7.11.1)| Length = 939 Score = 60.8 bits (146), Expect = 3e-09 Identities = 44/147 (29%), Positives = 79/147 (53%), Gaps = 3/147 (2%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTGISN 331 KY K+G G+ G +Y + TN VAIK N++ + + L +++ V++G + Sbjct: 619 KYANLVKIGQGASGGVYTAYEIGTNVSVAIKQMNLEKQPKKELIINEIL-VMKGSKHPNI 677 Query: 332 VKW---FGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 502 V + + ++GD V++ + G SL D+ + C L+ + + + ++ +EF+HSK Sbjct: 678 VNFIDSYVLKGDLWVIMEYMEGGSLTDVVTHCI--LTEGQIGAVCRETLSGLEFLHSKGV 735 Query: 503 LHRDIKPDNFLMGLGKRANQVYMIDFG 583 LHRDIK DN L+ + + + DFG Sbjct: 736 LHRDIKSDNILLSM---EGDIKLTDFG 759
>VPK1_VACCV (P16913) Serine/threonine-protein kinase 1 (EC 2.7.11.1) (Vaccinia| protein kinase 1) Length = 300 Score = 60.5 bits (145), Expect = 4e-09 Identities = 44/164 (26%), Positives = 82/164 (50%), Gaps = 18/164 (10%) Frame = +2 Query: 149 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLY-RVLQGGT-- 319 N++ +G +G G FG IY TN + +K+E + L E Y RVL+ Sbjct: 14 NQWVVGPLIGKGGFGSIYT-TN---DNNYVVKIE--PKANGSLFTEQAFYTRVLKPSVIE 67 Query: 320 -----------GISNVKWFG----VEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLML 454 G+ K FG + +Y LV++ LG L+ + N +L ++V+++ Sbjct: 68 EWKKSHNIKHVGLITCKAFGLYKSINVEYRFLVINRLGADLDAVIRANNNRLPKRSVMLI 127 Query: 455 ADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 +++N ++F+H + + H DIK N ++ + N++Y++D+GL Sbjct: 128 GIEILNTIQFMHEQGYSHGDIKASNIVLDQIDK-NKLYLVDYGL 170
>VPK1_VACCA (O57252) Serine/threonine-protein kinase 1 (EC 2.7.11.1) (Vaccinia| protein kinase 1) Length = 300 Score = 60.5 bits (145), Expect = 4e-09 Identities = 44/164 (26%), Positives = 82/164 (50%), Gaps = 18/164 (10%) Frame = +2 Query: 149 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLY-RVLQGGT-- 319 N++ +G +G G FG IY TN + +K+E + L E Y RVL+ Sbjct: 14 NQWVVGPLIGKGGFGSIYT-TN---DNNYVVKIE--PKANGSLFTEQAFYTRVLKPSVIE 67 Query: 320 -----------GISNVKWFG----VEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLML 454 G+ K FG + +Y LV++ LG L+ + N +L ++V+++ Sbjct: 68 EWKKSHNIKHVGLITCKAFGLYKSINVEYRFLVINRLGADLDAVIRANNNRLPKRSVMLI 127 Query: 455 ADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 +++N ++F+H + + H DIK N ++ + N++Y++D+GL Sbjct: 128 GIEILNTIQFMHEQGYSHGDIKASNIVLDQIDK-NKLYLVDYGL 170
>PAK1_HUMAN (Q13153) Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1)| (p21-activated kinase 1) (PAK-1) (P65-PAK) (Alpha-PAK) Length = 545 Score = 60.1 bits (144), Expect = 5e-09 Identities = 44/146 (30%), Positives = 74/146 (50%), Gaps = 2/146 (1%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQG-GTGIS 328 KY K+G G+ G +Y +V T +EVAIK N++ + + L +++ + + I Sbjct: 269 KYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIV 328 Query: 329 NVKWFGVEGDYNVLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFL 505 N + GD +VM+ L G SL D+ + + + + + + +EF+HS + Sbjct: 329 NYLDSYLVGDELWVVMEYLAGGSLTDVVT--ETCMDEGQIAAVCRECLQALEFLHSNQVI 386 Query: 506 HRDIKPDNFLMGLGKRANQVYMIDFG 583 HRDIK DN L+G+ V + DFG Sbjct: 387 HRDIKSDNILLGMD---GSVKLTDFG 409
>PAK1_RAT (P35465) Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1)| (p21-activated kinase 1) (PAK-1) (P68-PAK) (Alpha-PAK) (Protein kinase MUK2) Length = 544 Score = 60.1 bits (144), Expect = 5e-09 Identities = 44/146 (30%), Positives = 74/146 (50%), Gaps = 2/146 (1%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQG-GTGIS 328 KY K+G G+ G +Y +V T +EVAIK N++ + + L +++ + + I Sbjct: 268 KYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIV 327 Query: 329 NVKWFGVEGDYNVLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFL 505 N + GD +VM+ L G SL D+ + + + + + + +EF+HS + Sbjct: 328 NYLDSYLVGDELWVVMEYLAGGSLTDVVT--ETCMDEGQIAAVCRECLQALEFLHSNQVI 385 Query: 506 HRDIKPDNFLMGLGKRANQVYMIDFG 583 HRDIK DN L+G+ V + DFG Sbjct: 386 HRDIKSDNILLGMD---GSVKLTDFG 408
>CDPK4_PLAYO (Q7RJG2) Calcium-dependent protein kinase 4 (EC 2.7.11.1)| Length = 527 Score = 60.1 bits (144), Expect = 5e-09 Identities = 44/153 (28%), Positives = 78/153 (50%), Gaps = 8/153 (5%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVK-----TKHPQLLYESKLYRVLQGG 316 +Y+ + LG GSFGE+ L + T E AIK+ + K T LL E +L ++L Sbjct: 68 QYKGIKILGKGSFGEVILSKDKHTGHEYAIKVISKKHVKRKTDKQSLLREVELLKMLDH- 126 Query: 317 TGISNVKWFGVEGDYNVLVMDVL--GPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIH 490 I + F + +Y LV DV G +++ S ++ + Q+++ + ++H Sbjct: 127 INIMKLYEFFEDNNYYYLVSDVYSGGELFDEIIS--RKRFYEVDAARIIKQVLSGITYMH 184 Query: 491 SKSFLHRDIKPDNFLMGLGKRANQVY-MIDFGL 586 + +HRD+KP+N L+ + + + +IDFGL Sbjct: 185 KNNVVHRDLKPENILLETKNKEDMIIKIIDFGL 217
>CDPK4_PLABA (P62345) Calcium-dependent protein kinase 4 (EC 2.7.11.1) (PbCDPK4)| Length = 527 Score = 60.1 bits (144), Expect = 5e-09 Identities = 44/153 (28%), Positives = 78/153 (50%), Gaps = 8/153 (5%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVK-----TKHPQLLYESKLYRVLQGG 316 +Y+ + LG GSFGE+ L + T E AIK+ + K T LL E +L ++L Sbjct: 68 QYKGIKILGKGSFGEVILSKDKHTGHEYAIKVISKKHVKRKTDKQSLLREVELLKMLDH- 126 Query: 317 TGISNVKWFGVEGDYNVLVMDVL--GPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIH 490 I + F + +Y LV DV G +++ S ++ + Q+++ + ++H Sbjct: 127 INIMKLYEFFEDNNYYYLVSDVYSGGELFDEIIS--RKRFYEVDAARIIKQVLSGITYMH 184 Query: 491 SKSFLHRDIKPDNFLMGLGKRANQVY-MIDFGL 586 + +HRD+KP+N L+ + + + +IDFGL Sbjct: 185 KNNVVHRDLKPENILLETKNKEDMIIKIIDFGL 217
>CDPK2_PLAF7 (Q8ICR0) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (PfCDPK2)| Length = 508 Score = 60.1 bits (144), Expect = 5e-09 Identities = 46/168 (27%), Positives = 80/168 (47%), Gaps = 19/168 (11%) Frame = +2 Query: 140 RVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK------LENV-----------KTKH 268 ++ +KY + KLG G++G +Y G + TN+ AIK L+N+ K H Sbjct: 66 KLEDKYIIDEKLGQGTYGCVYKGIDKVTNQLYAIKEEKKDRLKNINRFFQEIEIMKKLDH 125 Query: 269 PQLLYESKLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFC--NRKLSLKT 442 P ++ KLY + +Y L+M++ S +LF N + K Sbjct: 126 PNIV---KLYETYEND-------------NYIYLIMELC--SGRELFDSIIENGSFTEKN 167 Query: 443 VLMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 + Q+ + + ++HS + +HRD+KP+NFL + + + +IDFGL Sbjct: 168 AATIMKQIFSAIFYLHSLNIVHRDLKPENFLFQSENKDSLLKIIDFGL 215
>VPK1_VACCC (P20505) Serine/threonine-protein kinase 1 (EC 2.7.11.1) (Vaccinia| protein kinase 1) Length = 300 Score = 60.1 bits (144), Expect = 5e-09 Identities = 44/164 (26%), Positives = 82/164 (50%), Gaps = 18/164 (10%) Frame = +2 Query: 149 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLY-RVLQGGT-- 319 N++ +G +G G FG IY TN + +K+E + L E Y RVL+ Sbjct: 14 NQWVVGPLIGKGGFGSIYT-TN---DNNYVVKIE--PKANGSLFTEQAFYTRVLKPSVIE 67 Query: 320 -----------GISNVKWFG----VEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLML 454 G+ K FG + +Y LV++ LG L+ + N +L ++V+++ Sbjct: 68 EWKKSHNIKHVGLITCKAFGLYKSINVEYRFLVINRLGVDLDAVIRANNNRLPKRSVMLI 127 Query: 455 ADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 +++N ++F+H + + H DIK N ++ + N++Y++D+GL Sbjct: 128 GIEILNTIQFMHEQGYSHGDIKASNIVLDQIDK-NKLYLVDYGL 170
>KCC1_YEAST (P27466) Calcium/calmodulin-dependent protein kinase I (EC| 2.7.11.17) Length = 446 Score = 60.1 bits (144), Expect = 5e-09 Identities = 38/151 (25%), Positives = 75/151 (49%), Gaps = 6/151 (3%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK------LENVKTKHPQLLYESKLYRVLQG 313 KY G+ LG+G+FG + N +T E+VA+K L+ K + L E + + L Sbjct: 36 KYVFGKTLGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLHH 95 Query: 314 GTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHS 493 ++ WF + + ++ G L D K + + + + ++++ V+++HS Sbjct: 96 PNIVAFKDWFESKDKFYIITQLAKGGELFDRI-LKKGKFTEEDAVRILVEILSAVKYMHS 154 Query: 494 KSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 ++ +HRD+KP+N L + + + DFG+ Sbjct: 155 QNIVHRDLKPENLLYIDKSDESPLVVADFGI 185
>CIPK1_ORYSA (Q6X4A2) CIPK-like protein 1 (EC 2.7.11.1) (OsCK1)| Length = 449 Score = 60.1 bits (144), Expect = 5e-09 Identities = 46/160 (28%), Positives = 82/160 (51%), Gaps = 6/160 (3%) Frame = +2 Query: 125 PPMEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKL---ENVKTKH---PQLLYE 286 P ++ RVG KY LGR +G G+F ++ N + +E VAIK+ E V+ KH Q+ E Sbjct: 11 PKVKRRVG-KYELGRTIGEGTFAKVRFAKNTENDEPVAIKILDKEKVQ-KHRLVEQIRRE 68 Query: 287 SKLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQM 466 ++++ + + G + +++ V G L ++ + N +L + Q+ Sbjct: 69 ICTMKLVKHPNVVRLFEVMGSKARIFIVLEYVTGGELFEIIA-TNGRLKEEEARKYFQQL 127 Query: 467 INRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 IN V++ HS+ HRD+K +N L+ + + + DFGL Sbjct: 128 INAVDYCHSRGVYHRDLKLENLLL---DASGNLKVSDFGL 164
>CDPK2_PLAFK (O15865) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (PfCDPK2)| Length = 512 Score = 60.1 bits (144), Expect = 5e-09 Identities = 46/168 (27%), Positives = 80/168 (47%), Gaps = 19/168 (11%) Frame = +2 Query: 140 RVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK------LENV-----------KTKH 268 ++ +KY + KLG G++G +Y G + TN+ AIK L+N+ K H Sbjct: 66 KLEDKYIIDEKLGQGTYGCVYKGIDKVTNQLYAIKEEKKDRLKNINRFFQEIEIMKKLDH 125 Query: 269 PQLLYESKLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFC--NRKLSLKT 442 P ++ KLY + +Y L+M++ S +LF N + K Sbjct: 126 PNIV---KLYETYEND-------------NYIYLIMELC--SGRELFDSIIENGSFTEKN 167 Query: 443 VLMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 + Q+ + + ++HS + +HRD+KP+NFL + + + +IDFGL Sbjct: 168 AATIMKQIFSAIFYLHSLNIVHRDLKPENFLFQSENKDSLLKIIDFGL 215
>PAK1_MOUSE (O88643) Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1)| (p21-activated kinase 1) (PAK-1) (P65-PAK) (Alpha-PAK) (CDC42/RAC effector kinase PAK-A) Length = 545 Score = 59.7 bits (143), Expect = 6e-09 Identities = 44/146 (30%), Positives = 74/146 (50%), Gaps = 2/146 (1%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQG-GTGIS 328 KY K+G G+ G +Y +V T +EVAIK N++ + + L +++ + + I Sbjct: 269 KYTPFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIV 328 Query: 329 NVKWFGVEGDYNVLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFL 505 N + GD +VM+ L G SL D+ + + + + + + +EF+HS + Sbjct: 329 NYLDSYLVGDELWVVMEYLAGGSLTDVVT--ETCMDEGQIAAVCRECLQALEFLHSNQVI 386 Query: 506 HRDIKPDNFLMGLGKRANQVYMIDFG 583 HRDIK DN L+G+ V + DFG Sbjct: 387 HRDIKSDNILLGMD---GSVKLTDFG 409
>YMX8_CAEEL (P34516) Putative serine/threonine-protein kinase K06H7.1 (EC| 2.7.11.1) Length = 346 Score = 59.7 bits (143), Expect = 6e-09 Identities = 41/152 (26%), Positives = 77/152 (50%), Gaps = 4/152 (2%) Frame = +2 Query: 143 VGNKYRLGRKLGSGSFGEIY-LGTNVQTNEEVAIKLENVKTKHPQLL-YESKLYRVLQGG 316 VG +Y++ +KLG G G ++ + + + A+K+E +L E ++ L Sbjct: 16 VGKRYKVVQKLGEGGCGSVFKVEDTSEKGQHYALKVEFKSQDAGNILKMEVQILSQLISK 75 Query: 317 TGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSK 496 ++ G + Y+ +VM +LG SL+ L L++ T + + ++ ++ +H Sbjct: 76 KHVAKCVASGKKERYSYMVMTLLGESLDSLLKKHGPFLNVSTQVRIGICILFGIKQVHDI 135 Query: 497 SFLHRDIKPDNFLMGLGKRANQVY--MIDFGL 586 +LHRD+KP N MG A++ Y ++DFGL Sbjct: 136 GYLHRDLKPANVAMGCKGSADERYFLVLDFGL 167
>CDPK4_PLAF7 (Q8IBS5) Calcium-dependent protein kinase 4 (EC 2.7.11.1)| Length = 527 Score = 59.7 bits (143), Expect = 6e-09 Identities = 44/153 (28%), Positives = 78/153 (50%), Gaps = 8/153 (5%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVK-----TKHPQLLYESKLYRVLQGG 316 +Y+ + LG GSFGE+ L + T E AIK+ + K T LL E +L ++L Sbjct: 68 QYKGIKILGKGSFGEVILSRDKHTGHEYAIKVISKKHVKRKTDKESLLREVELLKMLDH- 126 Query: 317 TGISNVKWFGVEGDYNVLVMDVL--GPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIH 490 I + F + +Y LV DV G +++ S ++ + Q+++ + ++H Sbjct: 127 INIMKLYEFFEDNNYYYLVSDVYTGGELFDEIIS--RKRFYEIDAARIIKQILSGITYMH 184 Query: 491 SKSFLHRDIKPDNFLMGLGKRANQVY-MIDFGL 586 + +HRD+KP+N L+ + + + +IDFGL Sbjct: 185 KNNVVHRDLKPENILLETKNKEDMIIKIIDFGL 217
>CSK2A_THEPA (P28547) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II)| Length = 348 Score = 59.7 bits (143), Expect = 6e-09 Identities = 43/150 (28%), Positives = 77/150 (51%), Gaps = 2/150 (1%) Frame = +2 Query: 143 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVLQGGT 319 V + Y + RK+G G F E++ G N T ++ IK L+ VK K ++ E K+ + L+GG Sbjct: 51 VPDSYEIVRKIGRGKFSEVFEGINTVTKDKCVIKILKPVKKK--KIKREIKILQNLRGGP 108 Query: 320 GISNVKWFGVEGDYNVLVMDVLGPSLEDL-FSFCNRKLSLKTVLMLADQMINRVEFIHSK 496 I +K + D ++ + + F LS++ + Q++ + + HS+ Sbjct: 109 NI--IKLLDIVKDPQSRTPSLIFEHVNNTDFKTLYPTLSIQDIKYYIYQLLKAMNYCHSQ 166 Query: 497 SFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 +HRDIKP N ++ K+ + +ID+GL Sbjct: 167 GIMHRDIKPHNVMIDHEKKI--LRLIDWGL 194
>NHK1_DROME (Q7KRY6) Nucleosomal histone kinase 1 (EC 2.7.11.1) (Protein| baellchen) Length = 599 Score = 59.7 bits (143), Expect = 6e-09 Identities = 48/170 (28%), Positives = 76/170 (44%), Gaps = 25/170 (14%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLGTNV-QTNEEVAIKLE----------------NVKTKH-PQL 277 ++R+G +G G FGEIY V + N + +K E N K + Q Sbjct: 46 QWRIGPSIGVGGFGEIYAACKVGEKNYDAVVKCEPHGNGPLFVEMHFYLRNAKLEDIKQF 105 Query: 278 LYESKL------YRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLK 439 + + L Y + G ++ K + +VM G L ++L Sbjct: 106 MQKHGLKSLGMPYILANGSVEVNGEK-------HRFIVMPRYGSDLTKFLEQNGKRLPEG 158 Query: 440 TVLMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGK-RANQVYMIDFGL 586 TV LA QM++ +++HS ++H D+K N L+GL K A Q Y++DFGL Sbjct: 159 TVYRLAIQMLDVYQYMHSNGYVHADLKAANILLGLEKGGAAQAYLVDFGL 208
>AAPK1_CAEEL (P45894) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMP-activated kinase 1) Length = 589 Score = 59.3 bits (142), Expect = 8e-09 Identities = 47/171 (27%), Positives = 81/171 (47%), Gaps = 22/171 (12%) Frame = +2 Query: 140 RVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLEN--------------------VK 259 ++GN + + +G G+FG + GT++QT +VAIK+ N K Sbjct: 20 KIGN-FVIKETIGKGAFGAVKRGTHIQTGYDVAIKILNRGRMKGLGTVNKTRNEIDNLQK 78 Query: 260 TKHPQLLYESKLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRK--LS 433 HP + ++L+RV+ + I LVM+++ +LFS+ RK L Sbjct: 79 LTHPHI---TRLFRVISTPSDI-------------FLVMELVSGG--ELFSYITRKGALP 120 Query: 434 LKTVLMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 ++ Q+I+ V + H+ +HRD+KP+N L+ K + + DFGL Sbjct: 121 IRESRRYFQQIISGVSYCHNHMIVHRDLKPENLLLDANK---NIKIADFGL 168
>SNF1_CANTR (O94168) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 619 Score = 59.3 bits (142), Expect = 8e-09 Identities = 52/178 (29%), Positives = 80/178 (44%), Gaps = 25/178 (14%) Frame = +2 Query: 128 PMEPRVGNKYRLGR-----KLGSGSFGEIYLGTNVQTNEEVAIKLENVKT---------- 262 P++P V R+GR LG GSFG++ L +V T ++VA+K+ N KT Sbjct: 38 PIDPNVNPANRIGRYQIIKTLGEGSFGKVKLAQHVGTGQKVALKIINRKTLAKSDMQGRV 97 Query: 263 ----------KHPQLLYESKLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFS 412 +HP ++ KLY V++ D ++V++ G L D + Sbjct: 98 EREISYLRLLRHPHII---KLYDVIK-------------SKDEIIMVIEFAGKELFD-YI 140 Query: 413 FCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 K+ Q+I VE+ H +HRD+KP+N L L + N V + DFGL Sbjct: 141 VQRGKMPEDEARRFFQQIIAAVEYCHRHKIVHRDLKPENLL--LDDQLN-VKIADFGL 195
>PIM1_RAT (P26794) Proto-oncogene serine/threonine-protein kinase Pim-1 (EC| 2.7.11.1) Length = 313 Score = 59.3 bits (142), Expect = 8e-09 Identities = 54/180 (30%), Positives = 89/180 (49%), Gaps = 14/180 (7%) Frame = +2 Query: 86 NLGGGSVACVRARPPMEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK------- 244 +L +A + + P+E ++Y++G LGSG FG +Y G V N VAIK Sbjct: 19 DLHANKLAPGKEKEPLE----SQYQVGPLLGSGGFGSVYSGIRVADNLPVAIKHVEKDRI 74 Query: 245 -----LENVKTKHPQLLYESKLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLF 409 L N T+ P + L +V G +G+ + + D VL+++ P ++DLF Sbjct: 75 SDWGELPN-GTRVPMEVV--LLKKVSSGFSGVIRLLDWFERPDSFVLILERPEP-VQDLF 130 Query: 410 SFCNRKLSLKTVLMLAD--QMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFG 583 F + +L+ L + Q++ V H+ LHRDIK +N L+ L + ++ +IDFG Sbjct: 131 DFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNR--GELKLIDFG 188
>VPK1_VARV (P33800) Serine/threonine-protein kinase 1 (EC 2.7.11.1)| Length = 300 Score = 58.9 bits (141), Expect = 1e-08 Identities = 41/164 (25%), Positives = 80/164 (48%), Gaps = 18/164 (10%) Frame = +2 Query: 149 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLY-RVLQ----- 310 N++ +G +G G FG IY + +K+E + L E Y RVL+ Sbjct: 14 NQWVVGPLIGKGGFGSIY----TTNDNNYVVKIE--PKANGSLFTEQAFYTRVLKPSVIE 67 Query: 311 --------GGTGISNVKWFG----VEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLML 454 G+ K FG + +Y LV++ LG L+ + N +L ++V+++ Sbjct: 68 EWKKSHHISHVGVITCKAFGLYKSINTEYRFLVINRLGVDLDAVIRANNNRLPKRSVMLV 127 Query: 455 ADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 +++N ++F+H + + H +IK N ++ + N++Y++D+GL Sbjct: 128 GIEILNTIQFMHEQGYSHGNIKASNIVLDQMDK-NKLYLVDYGL 170
>CDK9_CHICK (Q5ZKN1) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 372 Score = 58.9 bits (141), Expect = 1e-08 Identities = 46/157 (29%), Positives = 77/157 (49%), Gaps = 11/157 (7%) Frame = +2 Query: 149 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK---LENVKTKHP-QLLYESKLYRVLQGG 316 +KY K+G G+FGE++ + QT ++VA+K +EN K P L E K+ ++L+ Sbjct: 17 SKYEKLAKIGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLLKHE 76 Query: 317 TGISNVKWFGVEGD-YN------VLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINR 475 ++ ++ + YN LV D L L S + K +L + + ++N Sbjct: 77 NVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNTHVKFTLSEIKKVMQMLLNG 136 Query: 476 VEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 + +IH LHRD+K N L+ R + + DFGL Sbjct: 137 LYYIHRNKILHRDMKAANVLI---TRDGVLKLADFGL 170
>MDE3_SCHPO (O43077) Sporulation protein kinase mde3 (EC 2.7.11.1)| (Mei4-dependent protein 3) Length = 559 Score = 58.9 bits (141), Expect = 1e-08 Identities = 49/140 (35%), Positives = 75/140 (53%), Gaps = 10/140 (7%) Frame = +2 Query: 149 NKYRLGRKLGSGSFGEIYLGTNVQTN---EEVAIK-LENV---KTKHPQL-LYESKLYRV 304 ++Y + +KLG GSFG +YL + N E VA+K L+N K KH L L ES R Sbjct: 19 DRYLVKQKLGDGSFGTVYLAQRKEKNGLYETVAVKKLKNSSKPKPKHELLKLRESLALRK 78 Query: 305 LQGGTGISNVKWFGVEGDYNV-LVMDVLGPSLEDLFSFCNRKLSLK-TVLMLADQMINRV 478 + + ++ ++ N+ LVM+ + +L LF +L K T + Q+I+ + Sbjct: 79 ISKHPCLIDLLETFMDPYRNIFLVMEFMDCNLFQLFKRRQGRLFTKETAFNILLQIISGI 138 Query: 479 EFIHSKSFLHRDIKPDNFLM 538 E IH F+HRDIKP+N L+ Sbjct: 139 EHIHKHGFMHRDIKPENILV 158
>PKN1_THETN (Q8R9T6) Probable serine/threonine-protein kinase Sps1 (EC| 2.7.11.1) Length = 625 Score = 58.9 bits (141), Expect = 1e-08 Identities = 43/154 (27%), Positives = 72/154 (46%), Gaps = 6/154 (3%) Frame = +2 Query: 143 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTG 322 +GN+Y + K+G G ++Y N VAIK+ + + + K R Q Sbjct: 6 LGNRYEILEKIGEGGMAKVYKAKCHLLNRIVAIKILRPEFAADEN-FVKKFKRESQAAAS 64 Query: 323 ISNVKWFGV-----EGDYNVLVMD-VLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEF 484 +S+ G+ EGD +VM+ V G +L++L L +K + +A Q+ ++ Sbjct: 65 LSHPNIVGIYDVGQEGDIYYIVMEYVKGRTLKELIRENGGPLEVKRAVEIASQVCRALDH 124 Query: 485 IHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 H +HRDIKP N L+ + V + DFG+ Sbjct: 125 AHKNKIIHRDIKPQNILV---TDEDVVKVTDFGI 155
>PIM1_HUMAN (P11309) Proto-oncogene serine/threonine-protein kinase Pim-1 (EC| 2.7.11.1) Length = 404 Score = 58.9 bits (141), Expect = 1e-08 Identities = 52/170 (30%), Positives = 85/170 (50%), Gaps = 14/170 (8%) Frame = +2 Query: 116 RARPPMEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK------------LENVK 259 + + P+E ++Y++G LGSG FG +Y G V N VAIK L N Sbjct: 120 KEKEPLE----SQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPN-G 174 Query: 260 TKHPQLLYESKLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLK 439 T+ P + L +V G +G+ + + D VL+++ P ++DLF F + +L+ Sbjct: 175 TRVPMEVV--LLKKVSSGFSGVIRLLDWFERPDSFVLILERPEP-VQDLFDFITERGALQ 231 Query: 440 TVLMLAD--QMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFG 583 L + Q++ V H+ LHRDIK +N L+ L + ++ +IDFG Sbjct: 232 EELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNR--GELKLIDFG 279
>CDC7_MOUSE (Q9Z0H0) Cell division cycle 7-related protein kinase (EC 2.7.11.1)| (CDC7-related kinase) (muCdc7) Length = 564 Score = 58.5 bits (140), Expect = 1e-08 Identities = 44/153 (28%), Positives = 74/153 (48%), Gaps = 3/153 (1%) Frame = +2 Query: 137 PRVGNKYRLGRKLGSGSFGEIYLGT-NVQTNEEVAIKLEN-VKTKHP-QLLYESKLYRVL 307 P++ N ++ K+G G+F +YL T +Q E I L++ + T HP ++ E + V Sbjct: 46 PQLVNVSKIKDKIGEGTFSSVYLATAQLQEGHEEKIALKHLIPTSHPMRIAAELQCLTVA 105 Query: 308 QGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFI 487 G + +K+ + D+ V+ M L E N LS + V + ++ I Sbjct: 106 GGQDNVMGLKYCFRKNDHVVIAMPYL--EHESFLDILN-SLSFQEVREYMYNLFVALKRI 162 Query: 488 HSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 H +HRD+KP NFL +R + ++DFGL Sbjct: 163 HQFGIVHRDVKPSNFL--YNRRLKKYALVDFGL 193
>GSK3H_DROME (P83101) Putative glycogen synthase kinase-3 homolog (EC 2.7.11.26)| (GSK-3) (Protein gasket) Length = 501 Score = 58.5 bits (140), Expect = 1e-08 Identities = 49/154 (31%), Positives = 76/154 (49%), Gaps = 11/154 (7%) Frame = +2 Query: 155 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIK--LENVKTKHPQLLYESKLYRVLQGGTGIS 328 Y + +G+GSFG ++ V +NE VAIK L++ + K+ +L KL I Sbjct: 33 YTDAKVVGNGSFGVVFQAKMVPSNEMVAIKKVLQDRRFKNRELQIMRKLRH-----DNII 87 Query: 329 NVKWF----GVEGD--YNVLVMDVLGPSL---EDLFSFCNRKLSLKTVLMLADQMINRVE 481 +KWF G + D Y LVM+ L +L E ++ + L + V + Q++ + Sbjct: 88 TLKWFFFSSGEKRDEVYLNLVMEFLPETLYKVERQYARAKQTLPVNFVRLYMYQLLRSMG 147 Query: 482 FIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFG 583 ++HS F HRDIKP N L L + + DFG Sbjct: 148 YLHSLGFCHRDIKPQNML--LDSETGVLKLCDFG 179
>PAK3_RAT (Q62829) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) (Beta-PAK) (p65-PAK) Length = 544 Score = 58.5 bits (140), Expect = 1e-08 Identities = 42/146 (28%), Positives = 74/146 (50%), Gaps = 2/146 (1%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQG-GTGIS 328 KY K+G G+ G +Y ++ T +EVAIK N++ + + L +++ + + I Sbjct: 267 KYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIV 326 Query: 329 NVKWFGVEGDYNVLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFL 505 N + GD +VM+ L G SL D+ + + + + + + ++F+HS + Sbjct: 327 NYLDSYLVGDELWVVMEYLAGGSLTDVVT--ETCMDEGQIAAVCRECLQALDFLHSNQVI 384 Query: 506 HRDIKPDNFLMGLGKRANQVYMIDFG 583 HRDIK DN L+G+ V + DFG Sbjct: 385 HRDIKSDNILLGMD---GSVKLTDFG 407
>CSK23_ARATH (O64817) Probable casein kinase II subunit alpha (EC 2.7.11.1) (CK| II) Length = 333 Score = 58.5 bits (140), Expect = 1e-08 Identities = 42/146 (28%), Positives = 76/146 (52%), Gaps = 2/146 (1%) Frame = +2 Query: 155 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVLQGGTGISN 331 Y + RK+G G + E++ G NV TNE IK L+ VK K ++ E K+ + L GG I Sbjct: 34 YEVVRKVGRGKYSEVFEGKNVNTNERCVIKILKPVKKK--KIKREIKILQNLCGGPNI-- 89 Query: 332 VKWFGVEGDYNVLVMDVLGPSLEDL-FSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLH 508 VK + + D + ++ + + F L+ + +++ ++F HS+ +H Sbjct: 90 VKLYDIVRDEHSKTPSLVFEFVNSVDFKVLYPTLTDYDIRYYIYELLKALDFCHSQGIMH 149 Query: 509 RDIKPDNFLMGLGKRANQVYMIDFGL 586 RD+KP N + + + ++ +ID+GL Sbjct: 150 RDVKPHNVM--IDHQLRKLRLIDWGL 173
>CDK9_XENTR (Q6GLD8) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 376 Score = 58.5 bits (140), Expect = 1e-08 Identities = 47/161 (29%), Positives = 76/161 (47%), Gaps = 15/161 (9%) Frame = +2 Query: 149 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK---LENVKTKHP-QLLYESKLYRVLQGG 316 +KY K+G G+FGE++ + QT ++VA+K +EN K P L E K+ ++L+ Sbjct: 17 SKYERLAKIGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLLKHE 76 Query: 317 TGISNV-----KWFGVEGDYN------VLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQ 463 ++ + K YN LV D L L S + K +L + + Sbjct: 77 NVVNLIEICRTKISPTANQYNRCKGTIFLVFDFCEHDLAGLLSNAHVKFTLSEIKKVMQM 136 Query: 464 MINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 ++N + +IH LHRD+K N L+ R + + DFGL Sbjct: 137 LLNGLYYIHRNKILHRDMKAANVLI---TRDGVLKLADFGL 174
>CDK9A_XENLA (Q4V862) Cell division protein kinase 9-A (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9-A) Length = 376 Score = 58.5 bits (140), Expect = 1e-08 Identities = 47/161 (29%), Positives = 76/161 (47%), Gaps = 15/161 (9%) Frame = +2 Query: 149 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK---LENVKTKHP-QLLYESKLYRVLQGG 316 +KY K+G G+FGE++ + QT ++VA+K +EN K P L E K+ ++L+ Sbjct: 17 SKYERLAKIGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLLKHE 76 Query: 317 TGISNV-----KWFGVEGDYN------VLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQ 463 ++ + K YN LV D L L S + K +L + + Sbjct: 77 NVVNLIEICRTKVSPTANQYNRCKGTIFLVFDFCEHDLAGLLSNAHVKFTLSEIKKVMQM 136 Query: 464 MINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 ++N + +IH LHRD+K N L+ R + + DFGL Sbjct: 137 LLNGLYYIHRNKILHRDMKAANVLI---TRDGVLKLADFGL 174
>KC47_ORYSA (P29620) CDC2+/CDC28-related protein kinase R2 (EC 2.7.11.22)| Length = 424 Score = 58.5 bits (140), Expect = 1e-08 Identities = 47/153 (30%), Positives = 72/153 (47%), Gaps = 4/153 (2%) Frame = +2 Query: 140 RVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENV-KTKHP---QLLYESKLYRVL 307 RV ++Y LG G++G ++ + +T VAIK + K K L E KL + L Sbjct: 14 RVADRYLKREVLGEGTYGVVFKAVDTKTGNTVAIKKIRLGKYKEGVNFTALREIKLLKEL 73 Query: 308 QGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFI 487 + I + F +G+ + LV + + LE + N LS M+ + F Sbjct: 74 KDSNIIELIDAFPYKGNLH-LVFEFMETDLEAVIRDRNIVLSPADTKSYIQMMLKGLAFC 132 Query: 488 HSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 H K LHRD+KP+N L+G Q+ + DFGL Sbjct: 133 HKKWVLHRDMKPNNLLIGAD---GQLKLADFGL 162
>PAK3_PONPY (Q7YQL3) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) Length = 559 Score = 58.5 bits (140), Expect = 1e-08 Identities = 42/146 (28%), Positives = 74/146 (50%), Gaps = 2/146 (1%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQG-GTGIS 328 KY K+G G+ G +Y ++ T +EVAIK N++ + + L +++ + + I Sbjct: 282 KYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIV 341 Query: 329 NVKWFGVEGDYNVLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFL 505 N + GD +VM+ L G SL D+ + + + + + + ++F+HS + Sbjct: 342 NYLDSYLVGDELWVVMEYLAGGSLTDVVT--ETCMDEGQIAAVCRECLQALDFLHSNQVI 399 Query: 506 HRDIKPDNFLMGLGKRANQVYMIDFG 583 HRDIK DN L+G+ V + DFG Sbjct: 400 HRDIKSDNILLGMD---GSVKLTDFG 422
>PAK3_PANTR (Q7YQL4) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) Length = 559 Score = 58.5 bits (140), Expect = 1e-08 Identities = 42/146 (28%), Positives = 74/146 (50%), Gaps = 2/146 (1%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQG-GTGIS 328 KY K+G G+ G +Y ++ T +EVAIK N++ + + L +++ + + I Sbjct: 282 KYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIV 341 Query: 329 NVKWFGVEGDYNVLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFL 505 N + GD +VM+ L G SL D+ + + + + + + ++F+HS + Sbjct: 342 NYLDSYLVGDELWVVMEYLAGGSLTDVVT--ETCMDEGQIAAVCRECLQALDFLHSNQVI 399 Query: 506 HRDIKPDNFLMGLGKRANQVYMIDFG 583 HRDIK DN L+G+ V + DFG Sbjct: 400 HRDIKSDNILLGMD---GSVKLTDFG 422
>PAK3_MOUSE (Q61036) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) (Beta-PAK) (CDC42/RAC effector kinase PAK-B) Length = 559 Score = 58.5 bits (140), Expect = 1e-08 Identities = 42/146 (28%), Positives = 74/146 (50%), Gaps = 2/146 (1%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQG-GTGIS 328 KY K+G G+ G +Y ++ T +EVAIK N++ + + L +++ + + I Sbjct: 282 KYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIV 341 Query: 329 NVKWFGVEGDYNVLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFL 505 N + GD +VM+ L G SL D+ + + + + + + ++F+HS + Sbjct: 342 NYLDSYLVGDELWVVMEYLAGGSLTDVVT--ETCMDEGQIAAVCRECLQALDFLHSNQVI 399 Query: 506 HRDIKPDNFLMGLGKRANQVYMIDFG 583 HRDIK DN L+G+ V + DFG Sbjct: 400 HRDIKSDNILLGMD---GSVKLTDFG 422
>PAK3_HUMAN (O75914) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) (Beta-PAK) (Oligophrenin-3) Length = 559 Score = 58.5 bits (140), Expect = 1e-08 Identities = 42/146 (28%), Positives = 74/146 (50%), Gaps = 2/146 (1%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQG-GTGIS 328 KY K+G G+ G +Y ++ T +EVAIK N++ + + L +++ + + I Sbjct: 282 KYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIV 341 Query: 329 NVKWFGVEGDYNVLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFL 505 N + GD +VM+ L G SL D+ + + + + + + ++F+HS + Sbjct: 342 NYLDSYLVGDELWVVMEYLAGGSLTDVVT--ETCMDEGQIAAVCRECLQALDFLHSNQVI 399 Query: 506 HRDIKPDNFLMGLGKRANQVYMIDFG 583 HRDIK DN L+G+ V + DFG Sbjct: 400 HRDIKSDNILLGMD---GSVKLTDFG 422
>CSK2A_THEAN (Q4U925) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II)| (TaCKIIalpha) Length = 348 Score = 58.5 bits (140), Expect = 1e-08 Identities = 42/150 (28%), Positives = 77/150 (51%), Gaps = 2/150 (1%) Frame = +2 Query: 143 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVLQGGT 319 V + Y + RK+G G F E++ G N T ++ IK L+ VK K ++ E K+ + L+GG Sbjct: 51 VPDSYEIVRKIGRGKFSEVFEGLNTVTKDKCVIKILKPVKKK--KIKREIKILQNLRGGP 108 Query: 320 GISNVKWFGVEGDYNVLVMDVLGPSLEDL-FSFCNRKLSLKTVLMLADQMINRVEFIHSK 496 I +K + D ++ + + F L+++ + Q++ + + HS+ Sbjct: 109 NI--IKLLDIVKDPQSRTPSLIFEHVNNTDFKTLYPTLTIQDIKYYIYQLLKAMNYCHSQ 166 Query: 497 SFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 +HRDIKP N ++ K+ + +ID+GL Sbjct: 167 GIMHRDIKPHNVMIDHEKKI--LRLIDWGL 194
>VRK2_MOUSE (Q8BN21) Serine/threonine-protein kinase VRK2 (EC 2.7.11.1)| (Vaccinia-related kinase 2) Length = 503 Score = 58.5 bits (140), Expect = 1e-08 Identities = 54/170 (31%), Positives = 78/170 (45%), Gaps = 23/170 (13%) Frame = +2 Query: 146 GNKYRLGRKLGSGSFGEIYLG--TNVQTNE-EVAIKLENVKTKHPQLLYESKLYRVLQGG 316 GN++ LG+ +GSG FG IYL TN + IKLE ++ L E K Y+ Sbjct: 26 GNRWALGKMIGSGGFGLIYLAFPTNKPNKDARHVIKLEY--QENGPLFSELKFYQRAAKR 83 Query: 317 TGISNVKW----------------FGVEG----DYNVLVMDVLGPSLEDLFSFCNRKLSL 436 I KW FG+ Y +VM+ LG L+ L N Sbjct: 84 ECIQ--KWIQQRKLDYLGIPVFYGFGLTDFKGRSYRFMVMERLGIDLQKLLDQ-NGGFKK 140 Query: 437 KTVLMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 TVL L +M++ +E+IH ++H DIK N L+ ++VY+ D+GL Sbjct: 141 LTVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLDF-TNPDRVYLADYGL 189
>PIM1_FELCA (Q95LJ0) Proto-oncogene serine/threonine-protein kinase pim-1 (EC| 2.7.11.1) Length = 313 Score = 58.5 bits (140), Expect = 1e-08 Identities = 52/170 (30%), Positives = 85/170 (50%), Gaps = 14/170 (8%) Frame = +2 Query: 116 RARPPMEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK------------LENVK 259 + + P+E ++Y++G LGSG FG +Y G V N VAIK L N Sbjct: 29 KEKEPLE----SQYQVGPLLGSGGFGSVYSGIRVADNLPVAIKHVEKDRISDWGELPN-G 83 Query: 260 TKHPQLLYESKLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLK 439 T+ P + L +V G +G+ + + D VL+++ P ++DLF F + +L+ Sbjct: 84 TRVPMEVV--LLKKVSSGFSGVIRLLDWFERPDSFVLILERPEP-VQDLFDFITERGALQ 140 Query: 440 TVLMLAD--QMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFG 583 L + Q++ V H+ LHRDIK +N L+ L + ++ +IDFG Sbjct: 141 EELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNR--GELKLIDFG 188
>TAOK3_PONPY (Q5R4F3) Serine/threonine-protein kinase TAO3 (EC 2.7.11.1)| (Thousand and one amino acid protein 3) Length = 898 Score = 58.5 bits (140), Expect = 1e-08 Identities = 44/143 (30%), Positives = 65/143 (45%), Gaps = 5/143 (3%) Frame = +2 Query: 170 KLGSGSFGEIYLGTNVQTNEEVAIKL-----ENVKTKHPQLLYESKLYRVLQGGTGISNV 334 ++G GSFG +Y TN TNE VAIK + K +L E K R L+ I Sbjct: 29 EIGHGSFGAVYFATNAHTNEVVAIKKMSYSGKQTHEKWQDILKEVKFLRQLKHPNTI-EY 87 Query: 335 KWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRD 514 K ++ LVM+ S DL + L + + ++ + ++HS + +HRD Sbjct: 88 KGCYLKEHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAITHGALHGLAYLHSHALIHRD 147 Query: 515 IKPDNFLMGLGKRANQVYMIDFG 583 IK N L+ QV + DFG Sbjct: 148 IKAGNILL---TEPGQVKLADFG 167
>BRSK1_HUMAN (Q8TDC3) BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1| kinase) (SAD1A) Length = 794 Score = 58.2 bits (139), Expect = 2e-08 Identities = 52/178 (29%), Positives = 82/178 (46%), Gaps = 3/178 (1%) Frame = +2 Query: 62 VPP*LDALNLGGGSVACVRARPPMEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAI 241 VP D + GGG R VG YRL + LG G G + LG + T ++VAI Sbjct: 20 VPERKDEVAGGGGEEEEAEERGRHAQYVG-PYRLEKTLGKGQTGLVKLGVHCITGQKVAI 78 Query: 242 KLEN-VKTKHPQLLYESKLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFC 418 K+ N K L+ + +L+ +K V + L + + S +LF + Sbjct: 79 KIVNREKLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYL 138 Query: 419 NRK--LSLKTVLMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 +K L+ K Q+++ ++F HS S HRD+KP+N L+ N + + DFG+ Sbjct: 139 VKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLL---DEKNNIRIADFGM 193
>PAK2_RAT (Q64303) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) (Gamma-PAK) (p62-PAK) Length = 524 Score = 58.2 bits (139), Expect = 2e-08 Identities = 44/146 (30%), Positives = 70/146 (47%), Gaps = 2/146 (1%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENV-KTKHPQLLYESKLYRVLQGGTGIS 328 KY K+G G+ G ++ T+V +EVAIK N+ K +L+ L I Sbjct: 248 KYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKELKNPNIV 307 Query: 329 NVKWFGVEGDYNVLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFL 505 N + GD +VM+ L G SL D+ + + + + + + +EF+H+ + Sbjct: 308 NFLDSYLVGDELFVVMEYLAGGSLTDVVT--ETCMDEAQIAAVCRECLQALEFLHANQVI 365 Query: 506 HRDIKPDNFLMGLGKRANQVYMIDFG 583 HRDIK DN L+G+ V + DFG Sbjct: 366 HRDIKSDNVLLGM---EGSVKLTDFG 388
>PAK2_RABIT (Q29502) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) (Gamma-PAK) (p21-activated protein kinase I) (PAKI) Length = 524 Score = 58.2 bits (139), Expect = 2e-08 Identities = 44/146 (30%), Positives = 70/146 (47%), Gaps = 2/146 (1%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENV-KTKHPQLLYESKLYRVLQGGTGIS 328 KY K+G G+ G ++ T+V +EVAIK N+ K +L+ L I Sbjct: 248 KYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKELKNPNIV 307 Query: 329 NVKWFGVEGDYNVLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFL 505 N + GD +VM+ L G SL D+ + + + + + + +EF+H+ + Sbjct: 308 NFLDSYLVGDELFVVMEYLAGGSLTDVVT--ETCMDEAQIAAVCRECLQALEFLHANQVI 365 Query: 506 HRDIKPDNFLMGLGKRANQVYMIDFG 583 HRDIK DN L+G+ V + DFG Sbjct: 366 HRDIKSDNVLLGM---EGSVKLTDFG 388
>PAK2_MOUSE (Q8CIN4) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) Length = 524 Score = 58.2 bits (139), Expect = 2e-08 Identities = 44/146 (30%), Positives = 70/146 (47%), Gaps = 2/146 (1%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENV-KTKHPQLLYESKLYRVLQGGTGIS 328 KY K+G G+ G ++ T+V +EVAIK N+ K +L+ L I Sbjct: 248 KYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKELKNPNIV 307 Query: 329 NVKWFGVEGDYNVLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFL 505 N + GD +VM+ L G SL D+ + + + + + + +EF+H+ + Sbjct: 308 NFLDSYLVGDELFVVMEYLAGGSLTDVVT--ETCMDEAQIAAVCRECLQALEFLHANQVI 365 Query: 506 HRDIKPDNFLMGLGKRANQVYMIDFG 583 HRDIK DN L+G+ V + DFG Sbjct: 366 HRDIKSDNVLLGM---EGSVKLTDFG 388
>PAK2_HUMAN (Q13177) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) (PAK65) (Gamma-PAK) (S6/H4 kinase) Length = 524 Score = 58.2 bits (139), Expect = 2e-08 Identities = 44/146 (30%), Positives = 70/146 (47%), Gaps = 2/146 (1%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENV-KTKHPQLLYESKLYRVLQGGTGIS 328 KY K+G G+ G ++ T+V +EVAIK N+ K +L+ L I Sbjct: 248 KYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKELKNPNIV 307 Query: 329 NVKWFGVEGDYNVLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFL 505 N + GD +VM+ L G SL D+ + + + + + + +EF+H+ + Sbjct: 308 NFLDSYLVGDELFVVMEYLAGGSLTDVVT--ETCMDEAQIAAVCRECLQALEFLHANQVI 365 Query: 506 HRDIKPDNFLMGLGKRANQVYMIDFG 583 HRDIK DN L+G+ V + DFG Sbjct: 366 HRDIKSDNVLLGM---EGSVKLTDFG 388
>PIM1_BOVIN (Q9N0P9) Proto-oncogene serine/threonine-protein kinase pim-1 (EC| 2.7.11.1) Length = 313 Score = 58.2 bits (139), Expect = 2e-08 Identities = 52/170 (30%), Positives = 84/170 (49%), Gaps = 14/170 (8%) Frame = +2 Query: 116 RARPPMEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK------------LENVK 259 + + P+E ++Y++G LGSG FG +Y G V N VAIK L N Sbjct: 29 KEKEPLE----SQYQVGPLLGSGGFGSVYSGIRVADNLPVAIKHVEKDRISDWGELPN-G 83 Query: 260 TKHPQLLYESKLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLK 439 T+ P + L +V G +G+ + + D VL+++ P ++DLF F + +L+ Sbjct: 84 TRVPMEVV--LLKKVSSGFSGVIRLLDWFERPDSFVLILERPEP-VQDLFDFITERGALQ 140 Query: 440 TVLMLAD--QMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFG 583 L + Q++ V H LHRDIK +N L+ L + ++ +IDFG Sbjct: 141 EELARSFFWQVLEAVRHCHDCGVLHRDIKDENILIDLNR--GELKLIDFG 188
>KPK2_PLAFK (Q02595) Probable serine/threonine-protein kinase 2 (EC 2.7.11.1)| Length = 510 Score = 58.2 bits (139), Expect = 2e-08 Identities = 44/156 (28%), Positives = 75/156 (48%), Gaps = 10/156 (6%) Frame = +2 Query: 149 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVLQGGTGI 325 N Y L +K+G GSF Y+GTN+ V +K ++ K K + E ++ R + I Sbjct: 109 NVYVLNKKIGKGSFSTAYIGTNILYGNRVVVKEVDKSKVKESNVYTEIEVLRKVMHKYII 168 Query: 326 SNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNR---------KLSLKTVLMLADQMINRV 478 + + EG + LV++ L +LF + N K ++K VL+ + Sbjct: 169 KLISAYEQEG-FVYLVLEYLKGG--ELFEYLNNNGPYTEQVAKKAMKRVLI-------AL 218 Query: 479 EFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 E +HS +HRD+K +N ++ + + +IDFGL Sbjct: 219 EALHSNGVVHRDLKMENLMLENPNDPSSLKIIDFGL 254
>CDPK1_ORYSA (P53682) Calcium-dependent protein kinase, isoform 1 (EC 2.7.11.1)| (CDPK 1) Length = 534 Score = 57.8 bits (138), Expect = 2e-08 Identities = 47/157 (29%), Positives = 73/157 (46%), Gaps = 7/157 (4%) Frame = +2 Query: 137 PRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKL---ENVK--TKHPQLLYESKLYR 301 P V Y LGR+LG G FG+ YL T + T + A K N++ + + E ++ Sbjct: 67 PNVRELYTLGRELGQGQFGKTYLCTEISTGCQYACKTILKSNLRCVSDIEDVRREIQIMH 126 Query: 302 VLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRK--LSLKTVLMLADQMINR 475 L G I +K + +VM++ +LFS ++ S + L ++ Sbjct: 127 HLSGQKNIVTIKDTYEDEQAVHIVMELCAGG--ELFSKIQKRGHYSERKAAELIKIIVGI 184 Query: 476 VEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 +E HS +HRD+KP+NFL+ V IDFGL Sbjct: 185 IETCHSHGVMHRDLKPENFLLLDADDEFSVKAIDFGL 221
>ICK_HUMAN (Q9UPZ9) Serine/threonine-protein kinase ICK (EC 2.7.11.22)| (Intestinal cell kinase) (hICK) (MAK-related kinase) (MRK) (Laryngeal cancer kinase 2) (LCK2) Length = 632 Score = 57.8 bits (138), Expect = 2e-08 Identities = 43/150 (28%), Positives = 71/150 (47%), Gaps = 4/150 (2%) Frame = +2 Query: 149 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKT---KHPQLLYESKLYRVLQGGT 319 N+Y R+LG G++G + LG ++++ E +AIK K + L E K + L Sbjct: 2 NRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHAN 61 Query: 320 GISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKS 499 + +K E D+ + + + +L L N+ + + Q++ + FIH Sbjct: 62 -VVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHG 120 Query: 500 FLHRDIKPDNFL-MGLGKRANQVYMIDFGL 586 F HRD+KP+N L MG V + DFGL Sbjct: 121 FFHRDLKPENLLCMG----PELVKIADFGL 146
>SNF1_YEAST (P06782) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 633 Score = 57.8 bits (138), Expect = 2e-08 Identities = 48/168 (28%), Positives = 79/168 (47%), Gaps = 20/168 (11%) Frame = +2 Query: 143 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKT-------------------- 262 +GN Y++ + LG GSFG++ L + T ++VA+K+ N K Sbjct: 52 IGN-YQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLL 110 Query: 263 KHPQLLYESKLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKT 442 +HP ++ KLY V++ I ++V++ G L D + K+S + Sbjct: 111 RHPHII---KLYDVIKSKDEI-------------IMVIEYAGNELFD-YIVQRDKMSEQE 153 Query: 443 VLMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 Q+I+ VE+ H +HRD+KP+N L L + N V + DFGL Sbjct: 154 ARRFFQQIISAVEYCHRHKIVHRDLKPENLL--LDEHLN-VKIADFGL 198
>ARK1_SCHPO (O59790) Serine/threonine-protein kinase ark1 (EC 2.7.11.1)| (Aurora-related kinase 1) Length = 355 Score = 57.8 bits (138), Expect = 2e-08 Identities = 43/154 (27%), Positives = 74/154 (48%), Gaps = 11/154 (7%) Frame = +2 Query: 155 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTGI-SN 331 + +G+ LG G FG +YL +T VA+K T H L +SK+ + ++ I SN Sbjct: 89 FEIGKPLGKGKFGRVYLAKEKKTGFIVALK-----TLHKSELVQSKIEKQVRREIEIQSN 143 Query: 332 VKWFGVEGDYN--------VLVMDVLGPSLEDLFSFCNR--KLSLKTVLMLADQMINRVE 481 ++ + Y L+++ G +L+ R + S + QM N + Sbjct: 144 LRHKNILRLYGHFHDEKRIYLILEFAGRG--ELYQHLRRAKRFSEEVASKYIFQMANALS 201 Query: 482 FIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFG 583 ++H K +HRDIKP+N L+G+ ++ + DFG Sbjct: 202 YLHKKHVIHRDIKPENILLGID---GEIKLSDFG 232
>CSK2A_SPOFR (O76484) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II alpha| subunit) Length = 353 Score = 57.4 bits (137), Expect = 3e-08 Identities = 42/153 (27%), Positives = 76/153 (49%), Gaps = 9/153 (5%) Frame = +2 Query: 155 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVLQGGTGISN 331 Y+L RKLG G + E++ N+ NE+ +K L+ VK K ++ E K+ L+GGT I Sbjct: 39 YQLVRKLGRGKYSEVFEAINITNNEKCVVKILKPVKKK--KIKREIKILENLRGGTNIIT 96 Query: 332 VKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLAD--------QMINRVEFI 487 ++ +V D + + +F N + L+D +++ +++ Sbjct: 97 LQ---------AVVKDPVSRTPALIFEHVNNTDFKQLYQTLSDYDIRYYLYELLKALDYC 147 Query: 488 HSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 HS +HRD+KP N ++ R ++ +ID+GL Sbjct: 148 HSMGIMHRDVKPHNVMIDHDHR--KLRLIDWGL 178
>CDK9_RAT (Q641Z4) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 372 Score = 57.4 bits (137), Expect = 3e-08 Identities = 46/156 (29%), Positives = 75/156 (48%), Gaps = 11/156 (7%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK---LENVKTKHP-QLLYESKLYRVLQGGT 319 KY K+G G+FGE++ + QT ++VA+K +EN K P L E K+ ++L+ Sbjct: 18 KYEKLAKIGQGTFGEVFKAKHRQTGQKVALKKVLMENEKEGFPITALREIKILQLLKHEN 77 Query: 320 GISNVKWFGVEGD-YN------VLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRV 478 ++ ++ + YN LV D L L S K +L + + ++N + Sbjct: 78 VVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLLNGL 137 Query: 479 EFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 +IH LHRD+K N L+ R + + DFGL Sbjct: 138 YYIHRNKILHRDMKAANVLI---TRDGVLKLADFGL 170
>CDK9_MOUSE (Q99J95) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 372 Score = 57.4 bits (137), Expect = 3e-08 Identities = 46/156 (29%), Positives = 75/156 (48%), Gaps = 11/156 (7%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK---LENVKTKHP-QLLYESKLYRVLQGGT 319 KY K+G G+FGE++ + QT ++VA+K +EN K P L E K+ ++L+ Sbjct: 18 KYEKLAKIGQGTFGEVFKAKHRQTGQKVALKKVLMENEKEGFPITALREIKILQLLKHEN 77 Query: 320 GISNVKWFGVEGD-YN------VLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRV 478 ++ ++ + YN LV D L L S K +L + + ++N + Sbjct: 78 VVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLLNGL 137 Query: 479 EFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 +IH LHRD+K N L+ R + + DFGL Sbjct: 138 YYIHRNKILHRDMKAANVLI---TRDGVLKLADFGL 170
>CDK5_RAT (Q03114) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) Length = 292 Score = 57.4 bits (137), Expect = 3e-08 Identities = 43/155 (27%), Positives = 72/155 (46%), Gaps = 10/155 (6%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK----------LENVKTKHPQLLYESKLYR 301 KY K+G G++G ++ N +T+E VA+K + + + LL E K Sbjct: 3 KYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKN 62 Query: 302 VLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVE 481 +++ + + K LV + L+ F CN L + V L Q++ + Sbjct: 63 IVRLHDVLHSDKKL-------TLVFEFCDQDLKKYFDSCNGDLDPEIVKSLLFQLLKGLG 115 Query: 482 FIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 F HS++ LHRD+KP N L+ R ++ + DFGL Sbjct: 116 FCHSRNVLHRDLKPQNLLI---NRNGELKLADFGL 147
>ICK_RAT (Q62726) Serine/threonine-protein kinase ICK (EC 2.7.11.22)| (Intestinal cell kinase) (MAK-related kinase) (MRK) Length = 629 Score = 57.0 bits (136), Expect = 4e-08 Identities = 43/150 (28%), Positives = 71/150 (47%), Gaps = 4/150 (2%) Frame = +2 Query: 149 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKT---KHPQLLYESKLYRVLQGGT 319 N+Y ++LG G++G + LG ++++ E +AIK K + L E K + L Sbjct: 2 NRYTTIKQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHAN 61 Query: 320 GISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKS 499 I +K E D+ + + + +L L N+ + + Q++ + FIH Sbjct: 62 -IVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHG 120 Query: 500 FLHRDIKPDNFL-MGLGKRANQVYMIDFGL 586 F HRD+KP+N L MG V + DFGL Sbjct: 121 FFHRDLKPENLLCMG----PELVKIADFGL 146
>ICK_MOUSE (Q9JKV2) Serine/threonine-protein kinase ICK (EC 2.7.11.22)| (Intestinal cell kinase) (mICK) (MAK-related kinase) (MRK) Length = 629 Score = 57.0 bits (136), Expect = 4e-08 Identities = 43/150 (28%), Positives = 71/150 (47%), Gaps = 4/150 (2%) Frame = +2 Query: 149 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKT---KHPQLLYESKLYRVLQGGT 319 N+Y ++LG G++G + LG ++++ E +AIK K + L E K + L Sbjct: 2 NRYTTIKQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHAN 61 Query: 320 GISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKS 499 I +K E D+ + + + +L L N+ + + Q++ + FIH Sbjct: 62 -IVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHG 120 Query: 500 FLHRDIKPDNFL-MGLGKRANQVYMIDFGL 586 F HRD+KP+N L MG V + DFGL Sbjct: 121 FFHRDLKPENLLCMG----PELVKIADFGL 146
>PKN2_CLOAB (Q97IC2) Probable serine/threonine protein kinase CAC1728 (EC| 2.7.11.1) Length = 657 Score = 57.0 bits (136), Expect = 4e-08 Identities = 36/137 (26%), Positives = 67/137 (48%), Gaps = 5/137 (3%) Frame = +2 Query: 143 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVLQG-- 313 + N+Y++ ++G G +Y + N VA+K L++ T+ + +++ K Sbjct: 6 LSNRYKIEEEIGVGGTAVVYKAMDTLLNRHVAVKVLKHEFTEDEEFVFKFKREASAAARI 65 Query: 314 -GTGISNVKWFGVEGDYNVLVMD-VLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFI 487 I N+ G +G+ N +VM+ V G +L+ L N K+ ++ A Q+ + F Sbjct: 66 ANANIVNIYDVGADGNVNYIVMEYVAGKTLKKLIKE-NGKIEFNKIIDYATQIAKALNFA 124 Query: 488 HSKSFLHRDIKPDNFLM 538 H +HRDIKP N ++ Sbjct: 125 HKNGIVHRDIKPHNIMV 141
>PIT1_SCHPO (O14132) Sporulation protein kinase pit1 (EC 2.7.11.1)| Length = 650 Score = 56.6 bits (135), Expect = 5e-08 Identities = 45/153 (29%), Positives = 79/153 (51%), Gaps = 9/153 (5%) Frame = +2 Query: 155 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRV-----LQGGT 319 Y + RK+G G+FG +YL T ++EV + ++++K K ++ ++L V L Sbjct: 36 YNVVRKVGDGTFGSVYLATTKTPSKEV-VAIKSMKKKLAKVSDATRLREVHSLLRLSENE 94 Query: 320 GISNVKWFGVEGDYNV-LVMDVLGPSLEDLFSFC-NRKLSLKTVLMLADQMINRVEFIHS 493 I N+ ++ + +VM+ L +L L S N L+L+ V + Q+ + IH+ Sbjct: 95 NIVNIFDLYIDQFRCLHIVMEFLDCNLYQLISTRKNDPLTLEQVQDIMRQIFKGLNHIHT 154 Query: 494 KSFLHRDIKPDNFLMGLGKRAN--QVYMIDFGL 586 F HRD+KP+N L+ ++ V + DFGL Sbjct: 155 NGFFHRDMKPENILISSNSDSSSFNVKIADFGL 187
>PIM1_MOUSE (P06803) Proto-oncogene serine/threonine-protein kinase Pim-1 (EC| 2.7.11.1) Length = 397 Score = 56.6 bits (135), Expect = 5e-08 Identities = 51/170 (30%), Positives = 81/170 (47%), Gaps = 14/170 (8%) Frame = +2 Query: 116 RARPPMEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK------------LENVK 259 + + P+E ++Y++G LGSG FG +Y G V N VAIK L N Sbjct: 113 KEKEPLE----SQYQVGPLLGSGGFGSVYSGIRVADNLPVAIKHVEKDRISDWGELPNGT 168 Query: 260 TKHPQLLYESKLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLK 439 +++ K+ G I + WF D VL+++ P ++DLF F + +L+ Sbjct: 169 RVPMEVVLLKKVSSDFSG--VIRLLDWF-ERPDSFVLILERPEP-VQDLFDFITERGALQ 224 Query: 440 TVLMLAD--QMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFG 583 L Q++ V H+ LHRDIK +N L+ L + ++ +IDFG Sbjct: 225 EDLARGFFWQVLEAVRHCHNCGVLHRDIKDENILIDLSR--GEIKLIDFG 272
>TAOK3_HUMAN (Q9H2K8) Serine/threonine-protein kinase TAO3 (EC 2.7.11.1)| (Thousand and one amino acid protein 3) (Jun kinase-inhibitory kinase) (JNK/SAPK-inhibitory kinase) (Dendritic cell-derived protein kinase) (Cutaneous T-cell lymphoma tumor antigen H Length = 898 Score = 56.6 bits (135), Expect = 5e-08 Identities = 43/143 (30%), Positives = 65/143 (45%), Gaps = 5/143 (3%) Frame = +2 Query: 170 KLGSGSFGEIYLGTNVQTNEEVAIKL-----ENVKTKHPQLLYESKLYRVLQGGTGISNV 334 ++G GSFG +Y TN T+E VAIK + K +L E K R L+ I Sbjct: 29 EIGHGSFGAVYFATNAHTSEVVAIKKMSYSGKQTHEKWQDILKEVKFLRQLKHPNTI-EY 87 Query: 335 KWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRD 514 K ++ LVM+ S DL + L + + ++ + ++HS + +HRD Sbjct: 88 KGCYLKEHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAITHGALHGLAYLHSHALIHRD 147 Query: 515 IKPDNFLMGLGKRANQVYMIDFG 583 IK N L+ QV + DFG Sbjct: 148 IKAGNILL---TEPGQVKLADFG 167
>KIN11_ARATH (P92958) SNF1-related protein kinase catalytic alpha subunit KIN11| (EC 2.7.11.1) (AKIN11) (AKIN alpha1) Length = 512 Score = 56.6 bits (135), Expect = 5e-08 Identities = 45/149 (30%), Positives = 71/149 (47%), Gaps = 5/149 (3%) Frame = +2 Query: 155 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVK-----TKHPQLLYESKLYRVLQGGT 319 Y+LG+ LG GSFG++ + +V T +VAIK+ N + ++ E K+ R+ Sbjct: 20 YKLGKTLGIGSFGKVKIAEHVVTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFMHPH 79 Query: 320 GISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKS 499 I + D V++ V L D + +L Q+I+ VE+ H Sbjct: 80 IIRQYEVIETTSDIYVVMEYVKSGELFD-YIVEKGRLQEDEARNFFQQIISGVEYCHRNM 138 Query: 500 FLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 +HRD+KP+N L L R N + + DFGL Sbjct: 139 VVHRDLKPENLL--LDSRCN-IKIADFGL 164
>SNF1_CANAL (P52497) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 620 Score = 56.2 bits (134), Expect = 7e-08 Identities = 50/178 (28%), Positives = 79/178 (44%), Gaps = 25/178 (14%) Frame = +2 Query: 128 PMEPRVGNKYRLGR-----KLGSGSFGEIYLGTNVQTNEEVAIKLENVKT---------- 262 P++P R+GR LG GSFG++ L ++ T ++VA+K+ N KT Sbjct: 39 PIDPAANPANRIGRYQILKTLGEGSFGKVKLAQHLGTGQKVALKIINRKTLAKSDMQGRV 98 Query: 263 ----------KHPQLLYESKLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFS 412 +HP ++ KLY V++ D ++V++ G L D + Sbjct: 99 EREISYLRLLRHPHII---KLYDVIK-------------SKDEIIMVIEFAGKELFD-YI 141 Query: 413 FCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 K+ Q+I VE+ H +HRD+KP+N L L + N V + DFGL Sbjct: 142 VQRGKMPEDEARRFFQQIIAAVEYCHRHKIVHRDLKPENLL--LDDQLN-VKIADFGL 196
>CDK9B_XENLA (Q7ZX42) Cell division protein kinase 9-B (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9-B) Length = 376 Score = 56.2 bits (134), Expect = 7e-08 Identities = 46/161 (28%), Positives = 75/161 (46%), Gaps = 15/161 (9%) Frame = +2 Query: 149 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK---LENVKTKHP-QLLYESKLYRVLQGG 316 +KY K+G G+FGE++ + QT ++VA+K +EN K P L E K+ ++L+ Sbjct: 17 SKYERLAKIGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLLKHE 76 Query: 317 TGISNV-----KWFGVEGDYN------VLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQ 463 + + K YN LV D L L S + K ++ + + Sbjct: 77 NVVHLIEICRNKISPTANQYNRCKGTIFLVFDFCEHDLAGLLSNAHVKFTVAEIKKVMQM 136 Query: 464 MINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 ++N + +IH LHRD+K N L+ R + + DFGL Sbjct: 137 LLNGLYYIHRNKILHRDMKAANVLI---TRDGVLKLADFGL 174
>CDK9_HUMAN (P50750) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) (Serine/threonine-protein kinase PITALRE) (C-2K) (Cell division cycle 2-like protein kinase 4) Length = 372 Score = 56.2 bits (134), Expect = 7e-08 Identities = 45/157 (28%), Positives = 76/157 (48%), Gaps = 11/157 (7%) Frame = +2 Query: 149 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK---LENVKTKHP-QLLYESKLYRVLQGG 316 +KY K+G G+FGE++ + +T ++VA+K +EN K P L E K+ ++L+ Sbjct: 17 SKYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREIKILQLLKHE 76 Query: 317 TGISNVKWFGVEGD-YN------VLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINR 475 ++ ++ + YN LV D L L S K +L + + ++N Sbjct: 77 NVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLLNG 136 Query: 476 VEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 + +IH LHRD+K N L+ R + + DFGL Sbjct: 137 LYYIHRNKILHRDMKAANVLI---TRDGVLKLADFGL 170
>CSK2A_SCHPO (P40231) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II alpha| subunit) Length = 332 Score = 56.2 bits (134), Expect = 7e-08 Identities = 38/147 (25%), Positives = 75/147 (51%), Gaps = 1/147 (0%) Frame = +2 Query: 149 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTGIS 328 + Y + RK+G G + E++ G NV N + IK+ K+ ++ E K+ + L GG I Sbjct: 41 DNYEIIRKVGRGKYSEVFEGLNVLNNSKCIIKVLK-PVKYKKIKREIKILQNLAGGPNI- 98 Query: 329 NVKWFGVEGDYNVLVMDVLGPSLEDL-FSFCNRKLSLKTVLMLADQMINRVEFIHSKSFL 505 + + D ++ ++++ F LS + + +++ ++F HS+ + Sbjct: 99 -ISLLDIVRDPESKTPSLIFEFVDNIDFRTLYPTLSDYDIRYYSYELLKALDFCHSRGIM 157 Query: 506 HRDIKPDNFLMGLGKRANQVYMIDFGL 586 HRD+KP N ++ KR ++ +ID+GL Sbjct: 158 HRDVKPHNVMIDHKKR--KLRLIDWGL 182
>TAOK3_RAT (Q53UA7) Serine/threonine-protein kinase TAO3 (EC 2.7.11.1)| (Thousand and one amino acid protein 3) (Jun kinase-inhibitory kinase) (JNK/SAPK-inhibitory kinase) (Axotomy-related gene 357 protein) Length = 898 Score = 56.2 bits (134), Expect = 7e-08 Identities = 42/142 (29%), Positives = 65/142 (45%), Gaps = 4/142 (2%) Frame = +2 Query: 170 KLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYES--KLYRVLQGGTGISNVKWF 343 ++G GSFG +Y TN TNE VAIK + K ++ K R LQ + +++ Sbjct: 29 EIGHGSFGAVYFATNAHTNEVVAIKKMSYSGKQTHEKWQDILKEVRFLQQLKHPNTIEYK 88 Query: 344 G--VEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRDI 517 G ++ LVM+ S DL + L + + + + ++H S +HRDI Sbjct: 89 GCYLKEHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAITHGALQGLAYLHFHSLIHRDI 148 Query: 518 KPDNFLMGLGKRANQVYMIDFG 583 K N L+ QV + DFG Sbjct: 149 KAGNILL---TEPGQVKLADFG 167
>PKNX_STRCO (Q9XA16) Probable serine/threonine-protein kinase SCO3848 (EC| 2.7.11.1) Length = 673 Score = 55.8 bits (133), Expect = 9e-08 Identities = 47/160 (29%), Positives = 79/160 (49%), Gaps = 11/160 (6%) Frame = +2 Query: 140 RVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVLQGG 316 R+G +Y LG LG G E+Y + + +VA+K L + P ++++ R Q Sbjct: 6 RLGGRYELGPVLGRGGMAEVYHAHDTRLGRQVAVKTLRADLARDPS--FQARFRREAQSA 63 Query: 317 TGISN---VKWFGVEGDY--NV----LVMD-VLGPSLEDLFSFCNRKLSLKTVLMLADQM 466 +++ V + DY NV +VM+ V G +L +L RKL + L + + Sbjct: 64 ASLNHPAIVAVYDTGEDYIDNVSIPYIVMEYVDGSTLRELL-HSGRKLLPERTLEMTIGI 122 Query: 467 INRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 + +E+ H +HRDIKP N ++ R QV ++DFG+ Sbjct: 123 LQALEYSHRAGIVHRDIKPANVML---TRNGQVKVMDFGI 159
>KCC2D_RAT (P15791) Calcium/calmodulin-dependent protein kinase type II delta| chain (EC 2.7.11.17) (CaM-kinase II delta chain) (CaM kinase II delta subunit) (CaMK-II delta subunit) Length = 533 Score = 55.8 bits (133), Expect = 9e-08 Identities = 42/155 (27%), Positives = 72/155 (46%), Gaps = 6/155 (3%) Frame = +2 Query: 140 RVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKT----KHPQLLYESKLYRVL 307 R ++Y+L +LG G+F + + T +E A K+ N K H +L E+++ R+L Sbjct: 9 RFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLL 68 Query: 308 QGGTGISNVKWFGVEGDYNVLVMDVL--GPSLEDLFSFCNRKLSLKTVLMLADQMINRVE 481 + + EG ++ LV D++ G ED+ + S Q++ V Sbjct: 69 KHPNIVRLHDSISEEG-FHYLVFDLVTGGELFEDIVA--REYYSEADASHCIQQILESVN 125 Query: 482 FIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 H +HRD+KP+N L+ + V + DFGL Sbjct: 126 HCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGL 160
>SPKD_SYNY3 (P54735) Serine/threonine-protein kinase D (EC 2.7.11.1)| Length = 505 Score = 55.8 bits (133), Expect = 9e-08 Identities = 44/164 (26%), Positives = 81/164 (49%), Gaps = 13/164 (7%) Frame = +2 Query: 131 MEPRVGNKYRLGRKLGSGSFGEIYLG--TNVQTNEEVAIKL-------ENVKTKHPQLLY 283 M +V ++Y + + LGSG FG+ +L T + + + V IK N T+ Q L+ Sbjct: 1 MNVQVLDRYEIVKSLGSGGFGDTFLAKDTQIPSQKLVVIKRLKPANANSNTSTELIQKLF 60 Query: 284 ESKLYRVLQGGTGISNV----KWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLM 451 E + + G S + +F + ++ ++ + G SL ++ + + KT+L Sbjct: 61 EKEASVLEDLGEHNSQIPKLYSYFSNDNEFYLVQEYIQGVSLNEIAPISSEQA--KTIL- 117 Query: 452 LADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFG 583 ++ +++IHSK +HRDIKP+N + L + +IDFG Sbjct: 118 --SSLLTTLKYIHSKGIIHRDIKPENII--LRDSDHLPVLIDFG 157
>CDK9_BOVIN (Q5EAB2) Cell division protein kinase 9 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent kinase 9) Length = 372 Score = 55.8 bits (133), Expect = 9e-08 Identities = 45/156 (28%), Positives = 75/156 (48%), Gaps = 11/156 (7%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK---LENVKTKHP-QLLYESKLYRVLQGGT 319 KY K+G G+FGE++ + +T ++VA+K +EN K P L E K+ ++L+ Sbjct: 18 KYEKLAKIGQGTFGEVFKAKHRKTGQKVALKKVLMENEKEGFPITALREIKILQLLKHEN 77 Query: 320 GISNVKWFGVEGD-YN------VLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRV 478 ++ ++ + YN LV D L L S K +L + + ++N + Sbjct: 78 VVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLLNGL 137 Query: 479 EFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 +IH LHRD+K N L+ R + + DFGL Sbjct: 138 YYIHRNKILHRDMKAANVLI---TRDGVLKLADFGL 170
>CDK5_MOUSE (P49615) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) (CRK6) Length = 292 Score = 55.8 bits (133), Expect = 9e-08 Identities = 42/155 (27%), Positives = 71/155 (45%), Gaps = 10/155 (6%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK----------LENVKTKHPQLLYESKLYR 301 KY K+G G++G ++ N +T+E VA+K + + + LL E K Sbjct: 3 KYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKN 62 Query: 302 VLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVE 481 +++ + + K LV + L+ F CN L + V Q++ + Sbjct: 63 IVRLHDVLHSDKKL-------TLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLG 115 Query: 482 FIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 F HS++ LHRD+KP N L+ R ++ + DFGL Sbjct: 116 FCHSRNVLHRDLKPQNLLI---NRNGELKLADFGL 147
>CDK5_HUMAN (Q00535) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) Length = 292 Score = 55.8 bits (133), Expect = 9e-08 Identities = 42/155 (27%), Positives = 71/155 (45%), Gaps = 10/155 (6%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK----------LENVKTKHPQLLYESKLYR 301 KY K+G G++G ++ N +T+E VA+K + + + LL E K Sbjct: 3 KYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKN 62 Query: 302 VLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVE 481 +++ + + K LV + L+ F CN L + V Q++ + Sbjct: 63 IVRLHDVLHSDKKL-------TLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLG 115 Query: 482 FIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 F HS++ LHRD+KP N L+ R ++ + DFGL Sbjct: 116 FCHSRNVLHRDLKPQNLLI---NRNGELKLADFGL 147
>CDK5_BOVIN (Q02399) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Proline-directed protein kinase 33 kDa subunit) (PDPK) Length = 292 Score = 55.8 bits (133), Expect = 9e-08 Identities = 42/155 (27%), Positives = 71/155 (45%), Gaps = 10/155 (6%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK----------LENVKTKHPQLLYESKLYR 301 KY K+G G++G ++ N +T+E VA+K + + + LL E K Sbjct: 3 KYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKN 62 Query: 302 VLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVE 481 +++ + + K LV + L+ F CN L + V Q++ + Sbjct: 63 IVRLHDVLHSDKKL-------TLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLG 115 Query: 482 FIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 F HS++ LHRD+KP N L+ R ++ + DFGL Sbjct: 116 FCHSRNVLHRDLKPQNLLI---NRNGELKLADFGL 147
>BRSK2_HUMAN (Q8IWQ3) BR serine/threonine-protein kinase 2 (EC 2.7.11.1)| (Serine/threonine-protein kinase 29) (SAD1B) Length = 736 Score = 55.8 bits (133), Expect = 9e-08 Identities = 44/147 (29%), Positives = 72/147 (48%), Gaps = 3/147 (2%) Frame = +2 Query: 155 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLEN-VKTKHPQLLYESKLYRVLQGGTGISN 331 YRL + LG G G + LG + T ++VAIK+ N K L+ + +L+ Sbjct: 19 YRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESVLMKVEREIAILKLIEHPHV 78 Query: 332 VKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRK--LSLKTVLMLADQMINRVEFIHSKSFL 505 +K V + L + + S +LF + +K L+ K Q+I+ ++F HS S Sbjct: 79 LKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSIC 138 Query: 506 HRDIKPDNFLMGLGKRANQVYMIDFGL 586 HRD+KP+N L+ N + + DFG+ Sbjct: 139 HRDLKPENLLL---DEKNNIRIADFGM 162
>HUNK_PANTR (Q68UT7) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) Length = 714 Score = 55.8 bits (133), Expect = 9e-08 Identities = 46/157 (29%), Positives = 75/157 (47%), Gaps = 8/157 (5%) Frame = +2 Query: 140 RVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKH------PQLLYESKLYR 301 RVGN RKLG GSF ++ G +V T E+VAIK+ + K L E ++ + Sbjct: 57 RVGNYLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQ 116 Query: 302 VLQGGTGISNVKWFGVEGDYNVLVMDVL--GPSLEDLFSFCNRKLSLKTVLMLADQMINR 475 +++ + E Y LVM++ G + ++ ++L Q+I+ Sbjct: 117 MIRHPNITQLLDILETENSY-YLVMELCPGGNLMHKIYE--KKRLEESEARRYIRQLISA 173 Query: 476 VEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 VE +H +HRD+K +N L+ N + +IDFGL Sbjct: 174 VEHLHRAGVVHRDLKIENLLL---DEDNNIKLIDFGL 207
>HUNK_HUMAN (P57058) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) (Serine/threonine-protein kinase MAK-V) (B19) Length = 714 Score = 55.8 bits (133), Expect = 9e-08 Identities = 46/157 (29%), Positives = 75/157 (47%), Gaps = 8/157 (5%) Frame = +2 Query: 140 RVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKH------PQLLYESKLYR 301 RVGN RKLG GSF ++ G +V T E+VAIK+ + K L E ++ + Sbjct: 57 RVGNYLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQ 116 Query: 302 VLQGGTGISNVKWFGVEGDYNVLVMDVL--GPSLEDLFSFCNRKLSLKTVLMLADQMINR 475 +++ + E Y LVM++ G + ++ ++L Q+I+ Sbjct: 117 MIRHPNITQLLDILETENSY-YLVMELCPGGNLMHKIYE--KKRLEESEARRYIRQLISA 173 Query: 476 VEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 VE +H +HRD+K +N L+ N + +IDFGL Sbjct: 174 VEHLHRAGVVHRDLKIENLLL---DEDNNIKLIDFGL 207
>CDC7_YEAST (P06243) Cell division control protein 7 (EC 2.7.11.1)| Length = 507 Score = 55.8 bits (133), Expect = 9e-08 Identities = 47/164 (28%), Positives = 73/164 (44%), Gaps = 14/164 (8%) Frame = +2 Query: 137 PRVGNKYRLGRKLGSGSFGEIYLGTNVQT--------------NEEVAIKLENVKTKHPQ 274 P + N+Y+L K+G G+F +Y ++ + VA+K V T PQ Sbjct: 27 PGIENEYKLIDKIGEGTFSSVYKAKDITGKITKKFASHFWNYGSNYVALKKIYV-TSSPQ 85 Query: 275 LLYESKLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLML 454 +Y +L TG S V V+ VL + F R L +K + Sbjct: 86 RIYNE--LNLLYIMTGSSRVAPLCDAKRVRDQVIAVLPYYPHEEFRTFYRDLPIKGIKKY 143 Query: 455 ADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 +++ ++F+HSK +HRDIKP NFL L + ++DFGL Sbjct: 144 IWELLRALKFVHSKGIIHRDIKPTNFLFNL--ELGRGVLVDFGL 185
>CC2H1_TRYCO (P54664) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| Length = 301 Score = 55.5 bits (132), Expect = 1e-07 Identities = 41/152 (26%), Positives = 74/152 (48%), Gaps = 4/152 (2%) Frame = +2 Query: 143 VGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK---LENVKTKHP-QLLYESKLYRVLQ 310 +G++Y+ K+G GS+G +Y ++ T+ VA+K LE+V+ P + E + + L+ Sbjct: 1 MGSRYQRLEKIGEGSYGVVYRARDITTDVIVALKRIRLESVEEGVPCTAIREISILKELR 60 Query: 311 GGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIH 490 + + E N LV + + L+ + L T+ ++ V F H Sbjct: 61 HENIVRLLDVCHSENRLN-LVFEYMEMDLKKYMDRASGNLDPATIQEFMRSLLKGVRFCH 119 Query: 491 SKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 ++ LHRD+KP N L+ R ++ + DFGL Sbjct: 120 ERNVLHRDLKPPNLLI---SREKELKLADFGL 148
>CSK2A_DROME (P08181) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II alpha| subunit) Length = 335 Score = 55.5 bits (132), Expect = 1e-07 Identities = 42/153 (27%), Positives = 74/153 (48%), Gaps = 9/153 (5%) Frame = +2 Query: 155 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVLQGGTGISN 331 Y+L RKLG G + E++ N+ T E+ +K L+ VK K ++ E K+ L+GGT I Sbjct: 36 YQLVRKLGRGKYSEVFEAINITTTEKCVVKILKPVKKK--KIKREIKILENLRGGTNIIT 93 Query: 332 VKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLAD--------QMINRVEFI 487 + +V D + + +F N + L D +++ +++ Sbjct: 94 LL---------AVVKDPVSRTPALIFEHVNNTDFKQLYQTLTDYEIRYYLFELLKALDYC 144 Query: 488 HSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 HS +HRD+KP N ++ R ++ +ID+GL Sbjct: 145 HSMGIMHRDVKPHNVMIDHENR--KLRLIDWGL 175
>MARK1_MOUSE (Q8VHJ5) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) (ELKL motif serine/threonine-protein kinase 3) Length = 795 Score = 55.5 bits (132), Expect = 1e-07 Identities = 41/156 (26%), Positives = 78/156 (50%), Gaps = 6/156 (3%) Frame = +2 Query: 134 EPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHP----QLLYESKLYR 301 +P +GN YRL + +G G+F ++ L +V T EVA+K+ + +P +L E ++ + Sbjct: 54 QPHIGN-YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMK 112 Query: 302 VLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSF--CNRKLSLKTVLMLADQMINR 475 +L + VK F V L + + S ++F + + ++ K Q+++ Sbjct: 113 ILNHP---NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSA 169 Query: 476 VEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFG 583 V++ H K +HRD+K +N L+ + + DFG Sbjct: 170 VQYCHQKCIVHRDLKAENLLLDADM---NIKIADFG 202
>KPCD2_HUMAN (Q9BZL6) Serine/threonine-protein kinase D2 (EC 2.7.11.13)| (nPKC-D2) Length = 878 Score = 55.5 bits (132), Expect = 1e-07 Identities = 44/143 (30%), Positives = 73/143 (51%), Gaps = 6/143 (4%) Frame = +2 Query: 173 LGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHP-----QLLYESKLYRVLQGGTGISNVK 337 LGSG FG +Y G + +T +VA+K+ + K + P QL E + + L+ GI N++ Sbjct: 557 LGSGQFGVVYGGKHRKTGRDVAVKVID-KLRFPTKQESQLRNEVAILQSLRH-PGIVNLE 614 Query: 338 WFGVEGDYNVLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRD 514 + +VM+ L G LE + S +L + L Q++ + +H K+ +H D Sbjct: 615 CMFETPEKVFVVMEKLHGDMLEMILSSEKGRLPERLTKFLITQILVALRHLHFKNIVHCD 674 Query: 515 IKPDNFLMGLGKRANQVYMIDFG 583 +KP+N L+ QV + DFG Sbjct: 675 LKPENVLLASADPFPQVKLCDFG 697
>CDK5_XENLA (P51166) Cell division protein kinase 5 (EC 2.7.11.22) (Neuronal| cyclin-dependent kinase 5) Length = 292 Score = 55.5 bits (132), Expect = 1e-07 Identities = 42/155 (27%), Positives = 70/155 (45%), Gaps = 10/155 (6%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK----------LENVKTKHPQLLYESKLYR 301 KY K+G G++G ++ N T+E VA+K + + + LL E K Sbjct: 3 KYEKLEKIGEGTYGTVFKAKNRDTHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKN 62 Query: 302 VLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVE 481 +++ + + K LV + L+ F CN L + V Q++ + Sbjct: 63 IVRLHDVLHSDKKL-------TLVFEFCDQDLKKYFDSCNGDLDPEIVKSFMYQLLKGLA 115 Query: 482 FIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 F HS++ LHRD+KP N L+ R ++ + DFGL Sbjct: 116 FCHSRNVLHRDLKPQNLLI---NRNGELKLADFGL 147
>MARK1_RAT (O08678) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) Length = 793 Score = 55.5 bits (132), Expect = 1e-07 Identities = 41/156 (26%), Positives = 78/156 (50%), Gaps = 6/156 (3%) Frame = +2 Query: 134 EPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHP----QLLYESKLYR 301 +P +GN YRL + +G G+F ++ L +V T EVA+K+ + +P +L E ++ + Sbjct: 54 QPHIGN-YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMK 112 Query: 302 VLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSF--CNRKLSLKTVLMLADQMINR 475 +L + VK F V L + + S ++F + + ++ K Q+++ Sbjct: 113 ILNHP---NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSA 169 Query: 476 VEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFG 583 V++ H K +HRD+K +N L+ + + DFG Sbjct: 170 VQYCHQKCIVHRDLKAENLLLDADM---NIKIADFG 202
>TAOK1_RAT (O88664) Serine/threonine-protein kinase TAO1 (EC 2.7.11.1)| (Thousand and one amino acid protein 1) Length = 1001 Score = 55.5 bits (132), Expect = 1e-07 Identities = 41/143 (28%), Positives = 68/143 (47%), Gaps = 4/143 (2%) Frame = +2 Query: 167 RKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYES--KLYRVLQGGTGISNVKW 340 R++G GSFG +Y +V+TNE VAIK + K ++ K + LQ +++++ Sbjct: 32 REIGHGSFGAVYFARDVRTNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRIKHPNSIEY 91 Query: 341 FG--VEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRD 514 G + LVM+ S DL + L + + + + ++HS + +HRD Sbjct: 92 KGCYLREHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAITHGALQGLAYLHSHTMIHRD 151 Query: 515 IKPDNFLMGLGKRANQVYMIDFG 583 IK N L+ QV + DFG Sbjct: 152 IKAGNILL---TEPGQVKLADFG 171
>TAOK1_MOUSE (Q5F2E8) Serine/threonine-protein kinase TAO1 (EC 2.7.11.1)| (Thousand and one amino acid protein 1) Length = 1001 Score = 55.5 bits (132), Expect = 1e-07 Identities = 41/143 (28%), Positives = 68/143 (47%), Gaps = 4/143 (2%) Frame = +2 Query: 167 RKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYES--KLYRVLQGGTGISNVKW 340 R++G GSFG +Y +V+TNE VAIK + K ++ K + LQ +++++ Sbjct: 32 REIGHGSFGAVYFARDVRTNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRIKHPNSIEY 91 Query: 341 FG--VEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRD 514 G + LVM+ S DL + L + + + + ++HS + +HRD Sbjct: 92 KGCYLREHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAITHGALQGLAYLHSHTMIHRD 151 Query: 515 IKPDNFLMGLGKRANQVYMIDFG 583 IK N L+ QV + DFG Sbjct: 152 IKAGNILL---TEPGQVKLADFG 171
>TAOK1_HUMAN (Q7L7X3) Serine/threonine-protein kinase TAO1 (EC 2.7.11.1)| (Thousand and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B) Length = 1001 Score = 55.5 bits (132), Expect = 1e-07 Identities = 41/143 (28%), Positives = 68/143 (47%), Gaps = 4/143 (2%) Frame = +2 Query: 167 RKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYES--KLYRVLQGGTGISNVKW 340 R++G GSFG +Y +V+TNE VAIK + K ++ K + LQ +++++ Sbjct: 32 REIGHGSFGAVYFARDVRTNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRIKHPNSIEY 91 Query: 341 FG--VEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRD 514 G + LVM+ S DL + L + + + + ++HS + +HRD Sbjct: 92 KGCYLREHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAITHGALQGLAYLHSHTMIHRD 151 Query: 515 IKPDNFLMGLGKRANQVYMIDFG 583 IK N L+ QV + DFG Sbjct: 152 IKAGNILL---TEPGQVKLADFG 171
>HUNK_MOUSE (O88866) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) (Serine/threonine-protein kinase MAK-V) Length = 714 Score = 55.5 bits (132), Expect = 1e-07 Identities = 46/157 (29%), Positives = 75/157 (47%), Gaps = 8/157 (5%) Frame = +2 Query: 140 RVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKH------PQLLYESKLYR 301 RVGN RKLG GSF ++ G +V T E+VAIK+ + K L E ++ + Sbjct: 57 RVGNYLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQ 116 Query: 302 VLQGGTGISNVKWFGVEGDYNVLVMDVL--GPSLEDLFSFCNRKLSLKTVLMLADQMINR 475 +++ + E Y LVM++ G + ++ ++L Q+I+ Sbjct: 117 MIRHPNITQLLDILETENSY-YLVMELCPGGNLMHKIYE--KKRLDEAEARRYIRQLISA 173 Query: 476 VEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 VE +H +HRD+K +N L+ N + +IDFGL Sbjct: 174 VEHLHRAGVVHRDLKIENLLL---DEDNNIKLIDFGL 207
>CCRK_HUMAN (Q8IZL9) Cell cycle-related kinase (EC 2.7.11.22)| (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) Length = 346 Score = 55.1 bits (131), Expect = 1e-07 Identities = 39/150 (26%), Positives = 72/150 (48%), Gaps = 4/150 (2%) Frame = +2 Query: 149 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK---LENVKTKHP-QLLYESKLYRVLQGG 316 ++Y + ++G G+ G ++ +V+T E VA+K L ++ P Q L E K + ++ Sbjct: 2 DQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMEDN 61 Query: 317 TGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSK 496 + +K G VL + + L ++ R L+ V ++ V F H+ Sbjct: 62 QYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHAN 121 Query: 497 SFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 + +HRD+KP N L+ + Q+ + DFGL Sbjct: 122 NIVHRDLKPANLLI---SASGQLKIADFGL 148
>TAOK3_XENLA (Q6DD27) Serine/threonine-protein kinase TAO3 (EC 2.7.11.1)| (Thousand and one amino acid protein 3) Length = 896 Score = 55.1 bits (131), Expect = 1e-07 Identities = 41/143 (28%), Positives = 65/143 (45%), Gaps = 5/143 (3%) Frame = +2 Query: 170 KLGSGSFGEIYLGTNVQTNEEVAIKL-----ENVKTKHPQLLYESKLYRVLQGGTGISNV 334 ++G GSFG +Y TN TNE VA+K + + K ++ E K + L+ I Sbjct: 29 EIGHGSFGAVYFATNSTTNEIVAVKKMSYSGKQMNEKWQDIIKEVKFLQQLKHPNTI-EY 87 Query: 335 KWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRD 514 K ++ LVM+ S DL + L + + + + ++HS + +HRD Sbjct: 88 KGCYLKDHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAITHGALQGLAYLHSHNMIHRD 147 Query: 515 IKPDNFLMGLGKRANQVYMIDFG 583 IK N L+ QV + DFG Sbjct: 148 IKAGNILL---TEPGQVKLADFG 167
>BCK1_YEAST (Q01389) Serine/threonine-protein kinase BCK1/SLK1/SSP31 (EC| 2.7.11.1) Length = 1478 Score = 55.1 bits (131), Expect = 1e-07 Identities = 42/156 (26%), Positives = 73/156 (46%), Gaps = 21/156 (13%) Frame = +2 Query: 164 GRKLGSGSFGEIYLGTNVQTNEEVAIKLENV---KTKHPQLLYESKLYR----VLQGGTG 322 G +G GSFG +YL NV T E +A+K V +++ +L + R L+ Sbjct: 1178 GEMIGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDH 1237 Query: 323 ISNVKWFGVEGD---YNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHS 493 ++ V++ G E Y++ + V G S+ L R + L Q++ + ++HS Sbjct: 1238 LNIVQYLGFENKNNIYSLFLEYVAGGSVGSLIRMYGR-FDEPLIKHLTTQVLKGLAYLHS 1296 Query: 494 KSFLHRDIKPDNFLM-----------GLGKRANQVY 568 K LHRD+K DN L+ G+ +++ +Y Sbjct: 1297 KGILHRDMKADNLLLDQDGICKISDFGISRKSKDIY 1332
>TAOK3_MOUSE (Q8BYC6) Serine/threonine-protein kinase TAO3 (EC 2.7.11.1)| (Thousand and one amino acid protein 3) Length = 898 Score = 55.1 bits (131), Expect = 1e-07 Identities = 42/143 (29%), Positives = 63/143 (44%), Gaps = 5/143 (3%) Frame = +2 Query: 170 KLGSGSFGEIYLGTNVQTNEEVAIKL-----ENVKTKHPQLLYESKLYRVLQGGTGISNV 334 ++G GSFG +Y TN TNE VA+K + K +L E K + L+ I Sbjct: 29 EIGHGSFGAVYFATNAHTNEVVAVKKMSYSGKQTHEKWQDILKEVKFLQQLKHPNTI-EY 87 Query: 335 KWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRD 514 K ++ LVM+ S DL + L + + + + ++H S +HRD Sbjct: 88 KGCYLKEHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAITHGALQGLAYLHFHSLIHRD 147 Query: 515 IKPDNFLMGLGKRANQVYMIDFG 583 IK N L+ QV + DFG Sbjct: 148 IKAGNILL---TEPGQVKLADFG 167
>KIN10_ARATH (Q38997) SNF1-related protein kinase catalytic alpha subunit KIN10| (EC 2.7.11.1) (AKIN10) (AKIN alpha2) Length = 535 Score = 55.1 bits (131), Expect = 1e-07 Identities = 49/166 (29%), Positives = 73/166 (43%), Gaps = 22/166 (13%) Frame = +2 Query: 155 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKT--------------------KHPQ 274 Y+LGR LG GSFG + + + T +VAIK+ N + HP Sbjct: 42 YKLGRTLGIGSFGRVKIAEHALTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFMHPH 101 Query: 275 LLYESKLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRK--LSLKTVL 448 ++ +LY V++ T I LVM+ + +LF + K L Sbjct: 102 II---RLYEVIETPTDI-------------YLVMEYVNSG--ELFDYIVEKGRLQEDEAR 143 Query: 449 MLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 Q+I+ VE+ H +HRD+KP+N L L + N V + DFGL Sbjct: 144 NFFQQIISGVEYCHRNMVVHRDLKPENLL--LDSKCN-VKIADFGL 186
>PKN2_BACSU (O34507) Probable serine/threonine-protein kinase yloP (EC| 2.7.11.1) Length = 648 Score = 55.1 bits (131), Expect = 1e-07 Identities = 39/155 (25%), Positives = 72/155 (46%), Gaps = 6/155 (3%) Frame = +2 Query: 140 RVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGT 319 R+ +Y++ R +G G +YL ++ + EVAIK+ + + R Q + Sbjct: 6 RISGRYQILRVIGGGGMANVYLAEDIILDREVAIKILRFDYANDNEFIR-RFRREAQSAS 64 Query: 320 GISN-----VKWFGVEGDYNVLVMD-VLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVE 481 + + + G E D +VM+ V G +L++ + N L K L + +Q+++ + Sbjct: 65 SLDHPNIVSIYDLGEEDDIYYIVMEYVEGMTLKEYIT-ANGPLHPKEALNIMEQIVSAIA 123 Query: 482 FIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 H +HRDIKP N L+ + + DFG+ Sbjct: 124 HAHQNQIVHRDIKPHNILI---DHMGNIKVTDFGI 155
>KCC1_EMENI (Q00771) Calcium/calmodulin-dependent protein kinase (EC 2.7.11.17)| (CMPK) Length = 414 Score = 54.7 bits (130), Expect = 2e-07 Identities = 39/148 (26%), Positives = 71/148 (47%), Gaps = 4/148 (2%) Frame = +2 Query: 155 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIKL---ENVKTKHPQLLYESKLYRVLQGGTGI 325 YR GR LG+G++G + ++ +VA+K+ NV+ + E L + L + Sbjct: 23 YRFGRTLGAGTYGIVREADC--SSGKVAVKIILKRNVRGNERMVYDELDLLQKLNHPHIV 80 Query: 326 SNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNR-KLSLKTVLMLADQMINRVEFIHSKSF 502 V WF + + ++ G L D C K + K Q+++ V ++H ++ Sbjct: 81 HFVDWFESKDKFYIVTQLATGGELFD--RICEYGKFTEKDASQTIRQVLDAVNYLHQRNI 138 Query: 503 LHRDIKPDNFLMGLGKRANQVYMIDFGL 586 +HRD+KP+N L +Q+ + DFG+ Sbjct: 139 VHRDLKPENLLYLTRDLDSQLVLADFGI 166
>KPCD3_MOUSE (Q8K1Y2) Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein| kinase C nu type) (nPKC-nu) Length = 889 Score = 54.7 bits (130), Expect = 2e-07 Identities = 44/143 (30%), Positives = 73/143 (51%), Gaps = 6/143 (4%) Frame = +2 Query: 173 LGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHP-----QLLYESKLYRVLQGGTGISNVK 337 LGSG FG +Y G + +T +VAIK+ + K + P QL E + + L GI N++ Sbjct: 581 LGSGQFGIVYGGKHRKTGRDVAIKVID-KMRFPTKQESQLRNEVAILQNLHH-PGIVNLE 638 Query: 338 WFGVEGDYNVLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRD 514 + +VM+ L G LE + S +L + + Q++ + +H K+ +H D Sbjct: 639 CMFETPERVFVVMEKLHGDMLEMILSSEKSRLPERITKFMVTQILVALRNLHFKNIVHCD 698 Query: 515 IKPDNFLMGLGKRANQVYMIDFG 583 +KP+N L+ + QV + DFG Sbjct: 699 LKPENVLLASAEPFPQVKLCDFG 721
>CDPK1_PLAYO (Q7RAH3) Calcium-dependent protein kinase 1 (EC 2.7.11.1)| Length = 534 Score = 54.7 bits (130), Expect = 2e-07 Identities = 45/170 (26%), Positives = 77/170 (45%), Gaps = 19/170 (11%) Frame = +2 Query: 134 EPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKL---------------ENVKTKH 268 E ++G Y RKLGSG++GE+ L + E AIK+ +N++ H Sbjct: 49 EGKIGESYFKVRKLGSGAYGEVLLCKEKNGHSEKAIKVIKKSQFDKGRYNDDNKNIEKFH 108 Query: 269 PQLLYESKLYRVLQGGTGISNVKWFGVEGD--YNVLVMDVL--GPSLEDLFSFCNRKLSL 436 ++ E L + L + +K F V D Y LV + G E + + K Sbjct: 109 EEIYNEISLLKSLDHP---NIIKLFDVFEDKKYFYLVTEFYEGGELFEQIIN--RHKFDE 163 Query: 437 KTVLMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 + Q+++ + ++H + +HRDIKP+N L+ + ++DFGL Sbjct: 164 CDAANIMKQILSGICYLHKHNIVHRDIKPENILLENKNSLLNIKIVDFGL 213
>MARK3_MOUSE (Q03141) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| (MPK-10) (ELKL motif kinase 2) Length = 753 Score = 54.7 bits (130), Expect = 2e-07 Identities = 41/156 (26%), Positives = 78/156 (50%), Gaps = 6/156 (3%) Frame = +2 Query: 134 EPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHP----QLLYESKLYR 301 +P +GN YRL + +G G+F ++ L ++ T EVAIK+ + +P +L E ++ + Sbjct: 50 QPHIGN-YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMK 108 Query: 302 VLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSF--CNRKLSLKTVLMLADQMINR 475 +L + VK F V L + + S ++F + + ++ K Q+++ Sbjct: 109 ILNHP---NIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSA 165 Query: 476 VEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFG 583 V++ H K +HRD+K +N L+ + + DFG Sbjct: 166 VQYCHQKRIVHRDLKAENLLLDADM---NIKIADFG 198
>PKNA_MYCTU (P65726) Probable serine/threonine-protein kinase pknA (EC| 2.7.11.1) Length = 431 Score = 54.7 bits (130), Expect = 2e-07 Identities = 47/167 (28%), Positives = 81/167 (48%), Gaps = 15/167 (8%) Frame = +2 Query: 131 MEPRVG----NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKL 295 M PRVG +YRL R + +G G+++ + + VA+K L++ + P+ + + Sbjct: 1 MSPRVGVTLSGRYRLQRLIATGGMGQVWEAVDNRLGRRVAVKVLKSEFSSDPEFIERFRA 60 Query: 296 YR---VLQGGTGISNVKWFGV-----EGDYNVLVMDVLGPSLEDLFSFCNR--KLSLKTV 445 + GI++V +G EG LVM+++ E L S R +LSL+ Sbjct: 61 EARTTAMLNHPGIASVHDYGESQMNGEGRTAYLVMELVNG--EPLNSVLKRTGRLSLRHA 118 Query: 446 LMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 L + +Q ++ H+ +HRD+KP N L+ QV + DFG+ Sbjct: 119 LDMLEQTGRALQIAHAAGLVHRDVKPGNILI---TPTGQVKITDFGI 162
>PKNA_MYCBO (P65727) Probable serine/threonine-protein kinase pknA (EC| 2.7.11.1) Length = 431 Score = 54.7 bits (130), Expect = 2e-07 Identities = 47/167 (28%), Positives = 81/167 (48%), Gaps = 15/167 (8%) Frame = +2 Query: 131 MEPRVG----NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKL 295 M PRVG +YRL R + +G G+++ + + VA+K L++ + P+ + + Sbjct: 1 MSPRVGVTLSGRYRLQRLIATGGMGQVWEAVDNRLGRRVAVKVLKSEFSSDPEFIERFRA 60 Query: 296 YR---VLQGGTGISNVKWFGV-----EGDYNVLVMDVLGPSLEDLFSFCNR--KLSLKTV 445 + GI++V +G EG LVM+++ E L S R +LSL+ Sbjct: 61 EARTTAMLNHPGIASVHDYGESQMNGEGRTAYLVMELVNG--EPLNSVLKRTGRLSLRHA 118 Query: 446 LMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 L + +Q ++ H+ +HRD+KP N L+ QV + DFG+ Sbjct: 119 LDMLEQTGRALQIAHAAGLVHRDVKPGNILI---TPTGQVKITDFGI 162
>CHK2_HUMAN (O96017) Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (Cds1)| Length = 543 Score = 54.7 bits (130), Expect = 2e-07 Identities = 41/155 (26%), Positives = 75/155 (48%), Gaps = 10/155 (6%) Frame = +2 Query: 149 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKL--------ENVKTKHPQLLYESKL--Y 298 ++Y + + LGSG+ GE+ L +T ++VAIK+ + + P L E+++ Sbjct: 218 DEYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEIL 277 Query: 299 RVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRV 478 + L I +F E Y VL + G + + N++L T + QM+ V Sbjct: 278 KKLNHPCIIKIKNFFDAEDYYIVLELMEGGELFDKVVG--NKRLKEATCKLYFYQMLLAV 335 Query: 479 EFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFG 583 +++H +HRD+KP+N L+ + + + DFG Sbjct: 336 QYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFG 370
>MARK1_HUMAN (Q9P0L2) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) Length = 795 Score = 54.7 bits (130), Expect = 2e-07 Identities = 38/141 (26%), Positives = 73/141 (51%), Gaps = 6/141 (4%) Frame = +2 Query: 134 EPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHP----QLLYESKLYR 301 +P +GN YRL + +G G+F ++ L +V T EVA+K+ + +P +L E ++ + Sbjct: 54 QPHIGN-YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMK 112 Query: 302 VLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSF--CNRKLSLKTVLMLADQMINR 475 +L + VK F V L + + S ++F + + ++ K Q+++ Sbjct: 113 ILNHP---NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSA 169 Query: 476 VEFIHSKSFLHRDIKPDNFLM 538 V++ H K +HRD+K +N L+ Sbjct: 170 VQYCHQKYIVHRDLKAENLLL 190
>PKND_CHLCV (Q822K5) Serine/threonine-protein kinase pknD (EC 2.7.11.1)| Length = 930 Score = 54.7 bits (130), Expect = 2e-07 Identities = 45/160 (28%), Positives = 80/160 (50%), Gaps = 16/160 (10%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-----LENVKTKHPQLLYESKLYRVLQGG 316 +Y + R +G G GE+YL + + +VA+K L + + + L E+K+ L Sbjct: 3 RYDIIRMIGKGGMGEVYLAYDPVCSRKVALKRIREDLSDNELLKKRFLREAKIAADLVH- 61 Query: 317 TGISNVKWFGVEGDYNVLVMDVL-GPSLEDLFSF---CN-------RKLSLKTVLMLADQ 463 G+ V + D M + G +L+ L C+ + S+ T L + + Sbjct: 62 PGVVPVFTICSDSDPVYYTMPYIEGYTLKSLLKSVWQCDSLPKDLAEQTSVATFLSIFHK 121 Query: 464 MINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFG 583 + + VE++HS+ LHRD+KPDN L+GL ++V ++D+G Sbjct: 122 ICSTVEYVHSRGILHRDLKPDNILLGL---FSEVVILDWG 158
>MARK3_RAT (Q8VHF0) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| Length = 797 Score = 54.7 bits (130), Expect = 2e-07 Identities = 41/156 (26%), Positives = 78/156 (50%), Gaps = 6/156 (3%) Frame = +2 Query: 134 EPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHP----QLLYESKLYR 301 +P +GN YRL + +G G+F ++ L ++ T EVAIK+ + +P +L E ++ + Sbjct: 50 QPHIGN-YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMK 108 Query: 302 VLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSF--CNRKLSLKTVLMLADQMINR 475 +L + VK F V L + + S ++F + + ++ K Q+++ Sbjct: 109 ILNHP---NIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSA 165 Query: 476 VEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFG 583 V++ H K +HRD+K +N L+ + + DFG Sbjct: 166 VQYCHQKRIVHRDLKAENLLLDADM---NIKITDFG 198
>KPCD3_HUMAN (O94806) Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein| kinase C nu type) (nPKC-nu) (Protein kinase EPK2) Length = 890 Score = 54.7 bits (130), Expect = 2e-07 Identities = 44/143 (30%), Positives = 73/143 (51%), Gaps = 6/143 (4%) Frame = +2 Query: 173 LGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHP-----QLLYESKLYRVLQGGTGISNVK 337 LGSG FG +Y G + +T +VAIK+ + K + P QL E + + L GI N++ Sbjct: 582 LGSGQFGIVYGGKHRKTGRDVAIKVID-KMRFPTKQESQLRNEVAILQNLHH-PGIVNLE 639 Query: 338 WFGVEGDYNVLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRD 514 + +VM+ L G LE + S +L + + Q++ + +H K+ +H D Sbjct: 640 CMFETPERVFVVMEKLHGDMLEMILSSEKSRLPERITKFMVTQILVALRNLHFKNIVHCD 699 Query: 515 IKPDNFLMGLGKRANQVYMIDFG 583 +KP+N L+ + QV + DFG Sbjct: 700 LKPENVLLASAEPFPQVKLCDFG 722
>PKNA_MYCLE (P54743) Probable serine/threonine-protein kinase pknA (EC| 2.7.11.1) Length = 437 Score = 54.3 bits (129), Expect = 3e-07 Identities = 46/167 (27%), Positives = 80/167 (47%), Gaps = 15/167 (8%) Frame = +2 Query: 131 MEPRVG----NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKL 295 M PR+G +YRL R + +G G+++ + + VA+K L+ + P+ + + Sbjct: 1 MSPRIGVMLSGRYRLHRLIATGGMGQVWEAVDSRLGRRVAVKVLKGEFSSDPEFIERFRA 60 Query: 296 YR---VLQGGTGISNVKWFGV-----EGDYNVLVMDVLGPSLEDLFSFCNR--KLSLKTV 445 + GI++V +G EG LVM+++ E L S R +LSL+ Sbjct: 61 EARTTAMLNHPGIASVHDYGESHMDGEGRTAYLVMELVNG--EPLNSVLKRTGRLSLRHA 118 Query: 446 LMLADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 L + +Q ++ H+ +HRD+KP N L+ QV + DFG+ Sbjct: 119 LDMLEQTGRALQIAHAAGLVHRDVKPGNILI---TPTGQVKITDFGI 162
>MAK_RAT (P20793) Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male| germ cell-associated kinase) Length = 622 Score = 54.3 bits (129), Expect = 3e-07 Identities = 44/150 (29%), Positives = 69/150 (46%), Gaps = 4/150 (2%) Frame = +2 Query: 149 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKT---KHPQLLYESKLYRVLQGGT 319 N+Y R+LG G++G + +G + ++ E VAIK K L E K + L Sbjct: 2 NRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHAN 61 Query: 320 GISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKS 499 I +K E D+ + + + +L L N+ + + Q++ + FIH Sbjct: 62 VIK-LKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHG 120 Query: 500 FLHRDIKPDNFL-MGLGKRANQVYMIDFGL 586 F HRD+KP+N L MG V + DFGL Sbjct: 121 FFHRDMKPENLLCMG----PELVKIADFGL 146
>CSK22_ARATH (Q08466) Casein kinase II subunit alpha-2 (EC 2.7.11.1) (CK II)| Length = 333 Score = 54.3 bits (129), Expect = 3e-07 Identities = 41/146 (28%), Positives = 73/146 (50%), Gaps = 2/146 (1%) Frame = +2 Query: 155 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVLQGGTGISN 331 Y + RK+G G + E++ G N+ NE+ IK L+ VK K ++ E K+ + L GG I Sbjct: 34 YEVVRKVGRGKYSEVFEGINMNNNEKCIIKILKPVKKK--KIRREIKILQNLCGGPNI-- 89 Query: 332 VKWFGVEGDYNVLVMDVLGPSLEDL-FSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLH 508 VK V D + ++ + F L+ + +++ ++F HS+ +H Sbjct: 90 VKLLDVVRDQHSKTPSLIFEYVNSTDFKVLYPTLTDYDIRYYIYELLKALDFCHSQGIMH 149 Query: 509 RDIKPDNFLMGLGKRANQVYMIDFGL 586 RD+KP N + + ++ +ID+GL Sbjct: 150 RDVKPHNVM--IDHELRKLRLIDWGL 173
>CDPK3_ORYSA (P53684) Calcium-dependent protein kinase, isoform 11 (EC 2.7.11.1)| (CDPK 11) Length = 542 Score = 54.3 bits (129), Expect = 3e-07 Identities = 46/151 (30%), Positives = 68/151 (45%), Gaps = 7/151 (4%) Frame = +2 Query: 155 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIKL---ENVKTKH--PQLLYESKLYRVLQGGT 319 Y +GRKLG G FG YL T + T E A K + TK + E ++ L G Sbjct: 79 YIIGRKLGQGQFGTTYLCTEINTGCEYACKTIPKRKLITKEDVEDVRREIQIMHHLSGHK 138 Query: 320 GISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRK--LSLKTVLMLADQMINRVEFIHS 493 + +K +G +VM++ +LF K S + L +++ V HS Sbjct: 139 NVVAIKDVYEDGQAVHIVMELCAGG--ELFDRIQEKGHYSERKAAELIRIIVSIVAMCHS 196 Query: 494 KSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 +HRD+KP+NFL+ + IDFGL Sbjct: 197 LGVMHRDLKPENFLLLDKDDDLSIKAIDFGL 227
>AURKB_MOUSE (O70126) Serine/threonine-protein kinase 12 (EC 2.7.11.1)| (Aurora-related kinase 2) (Serine/threonine-protein kinase 5) (STK-1) (Aurora-B) Length = 345 Score = 54.3 bits (129), Expect = 3e-07 Identities = 54/200 (27%), Positives = 90/200 (45%), Gaps = 10/200 (5%) Frame = +2 Query: 14 PAQTLATNLRNSSLAQ---VPP*LDALNLGGGSVACVRARPPMEPRVGNKYRLGRKLGSG 184 PA T A L N S +Q P A N GS A + +P + + +GR LG G Sbjct: 33 PATTSALALVNRSNSQSTAAPGQKLAENKSQGSTAS-QGSQNKQPFTIDNFEIGRPLGKG 91 Query: 185 SFGEIYLGTNVQTNEEVAIKL------ENVKTKHPQLLYESKLYRVLQGGTGISNVKWF- 343 FG +YL ++ VA+K+ E +H QL E ++ L+ + +F Sbjct: 92 KFGNVYLAREKKSRFIVALKILFKSQIEKEGVEH-QLRREIEIQAHLKHPNILQLYNYFY 150 Query: 344 GVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRDIKP 523 + Y +L G ++L +R + + +++ + + + H K +HRDIKP Sbjct: 151 DQQRIYLILEYAPRGELYKELQK--SRTFDEQRTATIMEELSDALTYCHKKKVIHRDIKP 208 Query: 524 DNFLMGLGKRANQVYMIDFG 583 +N L+GL ++ + DFG Sbjct: 209 ENLLLGL---QGELKIADFG 225
>CSK2A_MAIZE (P28523) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II)| (CK2-alpha) Length = 332 Score = 54.3 bits (129), Expect = 3e-07 Identities = 40/146 (27%), Positives = 74/146 (50%), Gaps = 2/146 (1%) Frame = +2 Query: 155 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVLQGGTGISN 331 Y + RK+G G + E++ G NV NE+ IK L+ VK K ++ E K+ + L GG I Sbjct: 34 YEVVRKVGRGKYSEVFEGINVNNNEKCIIKILKPVKKK--KIKREIKILQNLCGGPNI-- 89 Query: 332 VKWFGVEGDYNVLVMDVLGPSLEDL-FSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLH 508 VK + D + ++ + + F L+ + +++ +++ HS+ +H Sbjct: 90 VKLLDIVRDQHSKTPSLIFEYVNNTDFKVLYPTLTDYDIRYYIYELLKALDYCHSQGIMH 149 Query: 509 RDIKPDNFLMGLGKRANQVYMIDFGL 586 RD+KP N + + ++ +ID+GL Sbjct: 150 RDVKPHNVM--IDHELRKLRLIDWGL 173
>MAK_HUMAN (P20794) Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male| germ cell-associated kinase) Length = 623 Score = 54.3 bits (129), Expect = 3e-07 Identities = 44/150 (29%), Positives = 69/150 (46%), Gaps = 4/150 (2%) Frame = +2 Query: 149 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKT---KHPQLLYESKLYRVLQGGT 319 N+Y R+LG G++G + +G + ++ E VAIK K L E K + L Sbjct: 2 NRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHAN 61 Query: 320 GISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKS 499 I +K E D+ + + + +L L N+ + + Q++ + FIH Sbjct: 62 VIK-LKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHG 120 Query: 500 FLHRDIKPDNFL-MGLGKRANQVYMIDFGL 586 F HRD+KP+N L MG V + DFGL Sbjct: 121 FFHRDMKPENLLCMG----PELVKIADFGL 146
>AAPK1_PONPY (Q5RDH5) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 550 Score = 54.3 bits (129), Expect = 3e-07 Identities = 46/154 (29%), Positives = 78/154 (50%), Gaps = 5/154 (3%) Frame = +2 Query: 140 RVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGT 319 R+G+ Y LG LG G+FG++ +G + T +VA+K+ N + K L K+ R +Q Sbjct: 14 RIGH-YILGDTLGVGTFGKVKVGKHELTGHKVAVKILN-RQKIRSLDVVGKIRREIQNLK 71 Query: 320 GISN---VKWFGVEGDYNVLVMDVLGPSLEDLFSFC--NRKLSLKTVLMLADQMINRVEF 484 + +K + V + + M + S +LF + N +L K L Q+++ V++ Sbjct: 72 LFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDY 131 Query: 485 IHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 H +HRD+KP+N L+ A + DFGL Sbjct: 132 CHRHMVVHRDLKPENVLLDAHMNAK---IADFGL 162
>CDK4_XENLA (Q91727) Cell division protein kinase 4 (EC 2.7.11.22)| (Cyclin-dependent kinase 4) Length = 319 Score = 54.3 bits (129), Expect = 3e-07 Identities = 46/164 (28%), Positives = 79/164 (48%), Gaps = 12/164 (7%) Frame = +2 Query: 131 MEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQL----LYESKLY 298 M + +Y ++G G++G +Y ++Q+ + VA+K V+T L + E L Sbjct: 1 MSKEMKGQYEPVAEIGVGAYGTVYKARDLQSGKFVALKNVRVQTNENGLPLSTVREVTLL 60 Query: 299 RVLQGGTGISNVKWFGV----EGDYNVLVMDVLGPSLEDLFSFCNRK----LSLKTVLML 454 + L+ + VK V D V V +DL ++ ++ L L+T+ L Sbjct: 61 KRLEHFDHPNIVKLMDVCASARTDRETKVTLVFEHVDQDLKTYLSKVPPPGLPLETIKDL 120 Query: 455 ADQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 Q ++ +EF+H +HRD+KP+N L+ G QV + DFGL Sbjct: 121 MKQFLSGLEFLHLNCIVHRDLKPENILVTSG---GQVKLADFGL 161
>PKNA_ANASP (P54734) Serine/threonine-protein kinase pknA (EC 2.7.11.1)| Length = 564 Score = 53.9 bits (128), Expect = 3e-07 Identities = 52/169 (30%), Positives = 81/169 (47%), Gaps = 18/169 (10%) Frame = +2 Query: 131 MEPRVGNKYRLGRKLGSGSFGEIYLGTNVQ--TNEEVAIKLENVKTKHPQL--LYESKLY 298 ME + N+YR+ + LGSG FGE +L + Q +N +K +PQ+ L + + Sbjct: 1 MEQLLDNRYRVIKTLGSGGFGETFLAEDSQMPSNRRCVVKQLRPIHNNPQIYQLVQERFQ 60 Query: 299 R---VLQ-----GGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVL-- 448 R +L+ G + +F + V+ V G +L KL + VL Sbjct: 61 REAAILEDLGSYSGQIPTLYAYFQSNTQFYVVQEWVEGDTL-------TAKLKQQGVLSE 113 Query: 449 -MLADQMINR---VEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFG 583 + D +IN +E++HSK +HRDIKPDN + L R + +IDFG Sbjct: 114 SAVRDILINLLPVLEYVHSKRIIHRDIKPDNII--LRHRDGKPVLIDFG 160
>PIM2_MOUSE (Q62070) Serine/threonine-protein kinase Pim-2 (EC 2.7.11.1)| Length = 370 Score = 53.9 bits (128), Expect = 3e-07 Identities = 46/158 (29%), Positives = 74/158 (46%), Gaps = 14/158 (8%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKL---------ENVKTKHPQLLYESKLYRV 304 +YRLG LG G FG ++ G V +VAIK+ V L + L++V Sbjct: 90 EYRLGPLLGKGGFGTVFAGHRVTDRRQVAIKVISRNRVLGWSTVSDSVTCPLEVALLWKV 149 Query: 305 LQGGTG---ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRK--LSLKTVLMLADQMI 469 +G I + WF + +LV++ P+ +DLF + K L Q++ Sbjct: 150 GEGNGHPGVIRLLDWFETPEGF-MLVLERPMPA-QDLFDYITEKGPLGESCSRSFFTQVV 207 Query: 470 NRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFG 583 V+ H++ +HRDIK +N L+ L + + +IDFG Sbjct: 208 AAVQHCHARGVVHRDIKDENILIDLCR--GSIKLIDFG 243
>M3K2_MOUSE (Q61083) Mitogen-activated protein kinase kinase kinase 2 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2) Length = 619 Score = 53.9 bits (128), Expect = 3e-07 Identities = 39/146 (26%), Positives = 64/146 (43%), Gaps = 9/146 (6%) Frame = +2 Query: 125 PPMEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKL--- 295 P PR +RLG+ LG G+FG +YL +V T E+A+K + P+ E Sbjct: 346 PSRSPRAPTNWRLGKLLGQGAFGRVYLCYDVDTGRELAVKQVQFNPESPETSKEVNALEC 405 Query: 296 -YRVLQGGTGISNVKWFGVEGDYNVLVMDVL-----GPSLEDLFSFCNRKLSLKTVLMLA 457 ++L+ V+++G D + + G S++D L+ Sbjct: 406 EIQLLKNLLHERIVQYYGCLRDPQEKTLSIFMELSPGGSIKDQLK-AYGALTENVTRKYT 464 Query: 458 DQMINRVEFIHSKSFLHRDIKPDNFL 535 Q++ V ++HS +HRDIK N L Sbjct: 465 RQILEGVHYLHSNMIVHRDIKGANIL 490
>CSK21_RAT (P19139) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II)| Length = 391 Score = 53.9 bits (128), Expect = 3e-07 Identities = 42/153 (27%), Positives = 74/153 (48%), Gaps = 9/153 (5%) Frame = +2 Query: 155 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVLQGGTGISN 331 Y+L RKLG G + E++ N+ NE+V +K L+ VK K ++ E K+ L+GG I Sbjct: 39 YQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKK--KIKREIKILENLRGGPNIIT 96 Query: 332 VKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLAD--------QMINRVEFI 487 + +V D + + +F N + L D +++ +++ Sbjct: 97 LA---------DIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYC 147 Query: 488 HSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 HS +HRD+KP N ++ R ++ +ID+GL Sbjct: 148 HSMGIMHRDVKPHNVMIDHEHR--KLRLIDWGL 178
>CSK21_MOUSE (Q60737) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II)| Length = 391 Score = 53.9 bits (128), Expect = 3e-07 Identities = 42/153 (27%), Positives = 74/153 (48%), Gaps = 9/153 (5%) Frame = +2 Query: 155 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVLQGGTGISN 331 Y+L RKLG G + E++ N+ NE+V +K L+ VK K ++ E K+ L+GG I Sbjct: 39 YQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKK--KIKREIKILENLRGGPNIIT 96 Query: 332 VKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLAD--------QMINRVEFI 487 + +V D + + +F N + L D +++ +++ Sbjct: 97 LA---------DIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYC 147 Query: 488 HSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 HS +HRD+KP N ++ R ++ +ID+GL Sbjct: 148 HSMGIMHRDVKPHNVMIDHEHR--KLRLIDWGL 178
>CSK21_HUMAN (P68400) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II)| Length = 391 Score = 53.9 bits (128), Expect = 3e-07 Identities = 42/153 (27%), Positives = 74/153 (48%), Gaps = 9/153 (5%) Frame = +2 Query: 155 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVLQGGTGISN 331 Y+L RKLG G + E++ N+ NE+V +K L+ VK K ++ E K+ L+GG I Sbjct: 39 YQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKK--KIKREIKILENLRGGPNIIT 96 Query: 332 VKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLAD--------QMINRVEFI 487 + +V D + + +F N + L D +++ +++ Sbjct: 97 LA---------DIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYC 147 Query: 488 HSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 HS +HRD+KP N ++ R ++ +ID+GL Sbjct: 148 HSMGIMHRDVKPHNVMIDHEHR--KLRLIDWGL 178
>CSK21_CHICK (P21868) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II)| Length = 391 Score = 53.9 bits (128), Expect = 3e-07 Identities = 42/153 (27%), Positives = 74/153 (48%), Gaps = 9/153 (5%) Frame = +2 Query: 155 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVLQGGTGISN 331 Y+L RKLG G + E++ N+ NE+V +K L+ VK K ++ E K+ L+GG I Sbjct: 39 YQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKK--KIKREIKILENLRGGPNIIT 96 Query: 332 VKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLAD--------QMINRVEFI 487 + +V D + + +F N + L D +++ +++ Sbjct: 97 LA---------DIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYC 147 Query: 488 HSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 HS +HRD+KP N ++ R ++ +ID+GL Sbjct: 148 HSMGIMHRDVKPHNVMIDHEHR--KLRLIDWGL 178
>CSK21_BOVIN (P68399) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II)| Length = 391 Score = 53.9 bits (128), Expect = 3e-07 Identities = 42/153 (27%), Positives = 74/153 (48%), Gaps = 9/153 (5%) Frame = +2 Query: 155 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVLQGGTGISN 331 Y+L RKLG G + E++ N+ NE+V +K L+ VK K ++ E K+ L+GG I Sbjct: 39 YQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKK--KIKREIKILENLRGGPNIIT 96 Query: 332 VKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLAD--------QMINRVEFI 487 + +V D + + +F N + L D +++ +++ Sbjct: 97 LA---------DIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYC 147 Query: 488 HSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 HS +HRD+KP N ++ R ++ +ID+GL Sbjct: 148 HSMGIMHRDVKPHNVMIDHEHR--KLRLIDWGL 178
>AURKC_HUMAN (Q9UQB9) Serine/threonine-protein kinase 13 (EC 2.7.11.1)| (Aurora/Ipl1/Eg2 protein 2) (Aurora/Ipl1-related kinase 3) (Aurora-C) Length = 309 Score = 53.9 bits (128), Expect = 3e-07 Identities = 43/160 (26%), Positives = 74/160 (46%), Gaps = 7/160 (4%) Frame = +2 Query: 125 PPMEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK------LENVKTKHPQLLYE 286 P M + + +GR LG G FG +YL +++ VA+K +E +H QL E Sbjct: 33 PAMRRLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEH-QLRRE 91 Query: 287 SKLYRVLQGGTGISNVKWF-GVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQ 463 ++ LQ + +F Y +L G ++L + KL + + ++ Sbjct: 92 IEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQK--SEKLDEQRTATIIEE 149 Query: 464 MINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFG 583 + + + + H K +HRDIKP+N L+G +V + DFG Sbjct: 150 LADALTYCHDKKVIHRDIKPENLLLGF---RGEVKIADFG 186
>RIPK5_BRARE (Q4VSN1) Receptor-interacting serine/threonine-protein kinase 5 (EC| 2.7.11.1) (Dusty protein kinase) (Dusty PK) Length = 885 Score = 53.9 bits (128), Expect = 3e-07 Identities = 42/141 (29%), Positives = 68/141 (48%), Gaps = 6/141 (4%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKH-PQLLYESKLYRVLQGGTGI 325 K +LGR+LG G +G +YL + A+K + KH L E R L + Sbjct: 613 KPKLGRELGRGQYGVVYLCDSWAGRHPCALKSVVPPDDKHWNDLALEFHYTRSLPKHERL 672 Query: 326 SNVKWFGVEGDYN----VLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHS 493 N+ ++ Y+ + V+ ++ DL++ LSLK L++A ++ + F+HS Sbjct: 673 VNLHGSVIDHSYSGGSSIAVLLIMERLHRDLYTGLKAGLSLKERLLIALDVVEGIRFLHS 732 Query: 494 KSFLHRDIKPDNFLMGLGKRA 556 + LHRDIK N L+ RA Sbjct: 733 QGLLHRDIKLKNVLLDKQNRA 753
>CSK22_XENLA (P28020) Casein kinase II subunit alpha' (EC 2.7.11.1) (CK II)| Length = 392 Score = 53.9 bits (128), Expect = 3e-07 Identities = 42/153 (27%), Positives = 74/153 (48%), Gaps = 9/153 (5%) Frame = +2 Query: 155 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVLQGGTGISN 331 Y+L RKLG G + E++ N+ NE+V +K L+ VK K ++ E K+ L+GG I Sbjct: 39 YQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKK--KIKREIKILENLRGGPNIIT 96 Query: 332 VKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLAD--------QMINRVEFI 487 + +V D + + +F N + L D +++ +++ Sbjct: 97 LA---------DIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYC 147 Query: 488 HSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 HS +HRD+KP N ++ R ++ +ID+GL Sbjct: 148 HSMGIMHRDVKPHNVMIDHEHR--KLRLIDWGL 178
>ROCK1_RABIT (O77819) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (cAMP-dependent protein kinase ROCK-I) (CePKA) (Corneal epithelial Rho-associated-Ser/Thr kinase 1) (HEB Length = 1354 Score = 53.5 bits (127), Expect = 4e-07 Identities = 38/148 (25%), Positives = 70/148 (47%), Gaps = 5/148 (3%) Frame = +2 Query: 155 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIKL----ENVKTKHPQLLYESKLYRVLQGGTG 322 Y + + +G G+FGE+ L + T + A+KL E +K +E + Sbjct: 76 YEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPW 135 Query: 323 ISNVKWFGVEGDYNVLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKS 499 + + + + Y +VM+ + G L +L S N + K +++ ++ IHS Sbjct: 136 VVQLFYAFQDDRYLYMVMEYMPGGDLVNLMS--NYDVPEKWARFYTAEVVLALDAIHSMG 193 Query: 500 FLHRDIKPDNFLMGLGKRANQVYMIDFG 583 F+HRD+KPDN L+ ++ + + DFG Sbjct: 194 FIHRDVKPDNMLL---DKSGHLKLADFG 218
>ROCK1_MOUSE (P70335) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) Length = 1354 Score = 53.5 bits (127), Expect = 4e-07 Identities = 38/148 (25%), Positives = 70/148 (47%), Gaps = 5/148 (3%) Frame = +2 Query: 155 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIKL----ENVKTKHPQLLYESKLYRVLQGGTG 322 Y + + +G G+FGE+ L + T + A+KL E +K +E + Sbjct: 76 YEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPW 135 Query: 323 ISNVKWFGVEGDYNVLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKS 499 + + + + Y +VM+ + G L +L S N + K +++ ++ IHS Sbjct: 136 VVQLFYAFQDDRYLYMVMEYMPGGDLVNLMS--NYDVPEKWARFYTAEVVLALDAIHSMG 193 Query: 500 FLHRDIKPDNFLMGLGKRANQVYMIDFG 583 F+HRD+KPDN L+ ++ + + DFG Sbjct: 194 FIHRDVKPDNMLL---DKSGHLKLADFG 218
>ROCK1_HUMAN (Q13464) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen) Length = 1354 Score = 53.5 bits (127), Expect = 4e-07 Identities = 38/148 (25%), Positives = 70/148 (47%), Gaps = 5/148 (3%) Frame = +2 Query: 155 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIKL----ENVKTKHPQLLYESKLYRVLQGGTG 322 Y + + +G G+FGE+ L + T + A+KL E +K +E + Sbjct: 76 YEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPW 135 Query: 323 ISNVKWFGVEGDYNVLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKS 499 + + + + Y +VM+ + G L +L S N + K +++ ++ IHS Sbjct: 136 VVQLFYAFQDDRYLYMVMEYMPGGDLVNLMS--NYDVPEKWARFYTAEVVLALDAIHSMG 193 Query: 500 FLHRDIKPDNFLMGLGKRANQVYMIDFG 583 F+HRD+KPDN L+ ++ + + DFG Sbjct: 194 FIHRDVKPDNMLL---DKSGHLKLADFG 218
>MAK_MOUSE (Q04859) Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male| germ cell-associated kinase) (Protein kinase RCK) Length = 622 Score = 53.5 bits (127), Expect = 4e-07 Identities = 44/150 (29%), Positives = 69/150 (46%), Gaps = 4/150 (2%) Frame = +2 Query: 149 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKT---KHPQLLYESKLYRVLQGGT 319 N+Y ++LG G++G + +G + ++ E VAIK K L E K + L Sbjct: 2 NRYTTMKQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHAN 61 Query: 320 GISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKS 499 I +K E D+ V + + +L L N+ + + Q++ + FIH Sbjct: 62 VIK-LKEVIRENDHLYFVFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHG 120 Query: 500 FLHRDIKPDNFL-MGLGKRANQVYMIDFGL 586 F HRD+KP+N L MG V + DFGL Sbjct: 121 FFHRDMKPENLLCMG----PELVKIADFGL 146
>CCRK_RAT (Q4KM34) Cell cycle-related kinase (EC 2.7.11.22)| Length = 346 Score = 53.5 bits (127), Expect = 4e-07 Identities = 39/150 (26%), Positives = 72/150 (48%), Gaps = 4/150 (2%) Frame = +2 Query: 149 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK---LENVKTKHP-QLLYESKLYRVLQGG 316 ++Y + ++G G+ G ++ +V+T E VA+K L ++ P Q L E K + ++ Sbjct: 2 DQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQALREIKALQEIEDS 61 Query: 317 TGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSK 496 + +K G VL + + L ++ R L+ V ++ V F H+ Sbjct: 62 QYVVQLKAVFPHGAGFVLAFEFMLSDLAEVVRHAQRPLAPAQVKSYLQMLLKGVAFCHAN 121 Query: 497 SFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 + +HRD+KP N L+ + Q+ + DFGL Sbjct: 122 NIVHRDLKPANLLI---SASGQLKIADFGL 148
>CCRK_MOUSE (Q9JHU3) Cell cycle-related kinase (EC 2.7.11.22)| (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) (CDK-related protein kinase PNQLARE) Length = 346 Score = 53.5 bits (127), Expect = 4e-07 Identities = 39/150 (26%), Positives = 72/150 (48%), Gaps = 4/150 (2%) Frame = +2 Query: 149 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK---LENVKTKHP-QLLYESKLYRVLQGG 316 ++Y + ++G G+ G ++ +V+T E VA+K L ++ P Q L E K + ++ Sbjct: 2 DQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQALREIKALQEIEDS 61 Query: 317 TGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSK 496 + +K G VL + + L ++ R L+ V ++ V F H+ Sbjct: 62 QYVVQLKAVFPHGAGFVLAFEFMLSDLAEVVRHAQRPLAPAQVKSYLQMLLKGVAFCHAN 121 Query: 497 SFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 + +HRD+KP N L+ + Q+ + DFGL Sbjct: 122 NIVHRDLKPANLLI---SASGQLKIADFGL 148
>CSK21_ARATH (Q08467) Casein kinase II subunit alpha-1 (EC 2.7.11.1) (CK II)| Length = 333 Score = 53.5 bits (127), Expect = 4e-07 Identities = 41/146 (28%), Positives = 73/146 (50%), Gaps = 2/146 (1%) Frame = +2 Query: 155 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVLQGGTGISN 331 Y + RK+G G + E++ G NV + E+ IK L+ VK K ++ E K+ + L GG I Sbjct: 34 YEVVRKVGRGKYSEVFEGINVNSKEKCIIKILKPVKKK--KIRREIKILQNLCGGPNI-- 89 Query: 332 VKWFGVEGDYNVLVMDVLGPSLEDL-FSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLH 508 VK V D + ++ + F L+ + +++ ++F HS+ +H Sbjct: 90 VKLLDVVRDQHSKTPSLIFEYVNSTDFKVLYPTLTDYDIRYYIYELLKALDFCHSQGIMH 149 Query: 509 RDIKPDNFLMGLGKRANQVYMIDFGL 586 RD+KP N + + ++ +ID+GL Sbjct: 150 RDVKPHNVM--IDHELRKLRLIDWGL 173
>KCC1_METAN (O14408) Calcium/calmodulin-dependent protein kinase (EC 2.7.11.17)| Length = 382 Score = 53.5 bits (127), Expect = 4e-07 Identities = 38/150 (25%), Positives = 70/150 (46%), Gaps = 4/150 (2%) Frame = +2 Query: 149 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKL---ENVKTKHPQLLYESKLYRVLQGGT 319 +KY+ GR LG+G++G + + +VAIK+ +NVK + E + + L Sbjct: 21 SKYKFGRTLGAGTYGVVREADG--PSGKVAIKIILKKNVKGNEKMVYAELDMLQRLTHPH 78 Query: 320 GISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNR-KLSLKTVLMLADQMINRVEFIHSK 496 + V WF + ++ G L D C++ K + Q++ V+++H Sbjct: 79 IVKFVDWFESRDKFYIVTQLATGGELFD--RICDQGKFTEVDASQTIRQIMTAVDYLHDN 136 Query: 497 SFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 +HRD+KP+N L + + + DFG+ Sbjct: 137 DVVHRDLKPENLLYVTRDPDSDLVLADFGI 166
>STK6_HUMAN (O14965) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1) (Aurora-related kinase 1) (hARK1) (Aurora-A) (Breast-tumor-amplified kinase) Length = 403 Score = 53.5 bits (127), Expect = 4e-07 Identities = 43/150 (28%), Positives = 68/150 (45%), Gaps = 7/150 (4%) Frame = +2 Query: 155 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIK------LENVKTKHPQLLYESKLYRVLQGG 316 + +GR LG G FG +YL Q+ +A+K LE +H QL E ++ L+ Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEH-QLRREVEIQSHLRHP 191 Query: 317 TGISNVKWF-GVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHS 493 + +F Y +L LG +L K + ++ N + + HS Sbjct: 192 NILRLYGYFHDATRVYLILEYAPLGTVYRELQKLS--KFDEQRTATYITELANALSYCHS 249 Query: 494 KSFLHRDIKPDNFLMGLGKRANQVYMIDFG 583 K +HRDIKP+N L+G A ++ + DFG Sbjct: 250 KRVIHRDIKPENLLLG---SAGELKIADFG 276
>AURKC_MOUSE (O88445) Serine/threonine-protein kinase 13 (EC 2.7.11.1)| (Aurora/Ipl1/Eg2 protein 1) (Aurora-C) Length = 282 Score = 53.5 bits (127), Expect = 4e-07 Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 8/153 (5%) Frame = +2 Query: 149 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK------LENVKTKHPQLLYESKLYRVLQ 310 N + +GR LG G FG +YL + + VA+K +E +H QL E ++ LQ Sbjct: 14 NDFEIGRPLGRGKFGRVYLARLKENHFIVALKVLFKSEIEKEGLEH-QLRREVEIQAHLQ 72 Query: 311 GGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNR--KLSLKTVLMLADQMINRVEF 484 + +F D + ++ P E L+ R KL + + ++ + + + Sbjct: 73 HRNILRLYNYF--YDDTRIYLILEYAPGGE-LYKELQRHQKLDQQRTATIIQELSDALTY 129 Query: 485 IHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFG 583 H K +HRDIKP+N L+GL +V + DFG Sbjct: 130 CHEKKVIHRDIKPENLLLGLN---GEVKISDFG 159
>ROCK1_RAT (Q63644) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (p150 RhoA-binding kinase ROK beta) (Liver regeneration-related protein LRRG199) Length = 1369 Score = 53.5 bits (127), Expect = 4e-07 Identities = 38/148 (25%), Positives = 70/148 (47%), Gaps = 5/148 (3%) Frame = +2 Query: 155 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIKL----ENVKTKHPQLLYESKLYRVLQGGTG 322 Y + + +G G+FGE+ L + T + A+KL E +K +E + Sbjct: 76 YEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPW 135 Query: 323 ISNVKWFGVEGDYNVLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKS 499 + + + + Y +VM+ + G L +L S N + K +++ ++ IHS Sbjct: 136 VVQLFYAFQDDRYLYMVMEYMPGGDLVNLMS--NYDVPEKWARFYTAEVVLALDAIHSMG 193 Query: 500 FLHRDIKPDNFLMGLGKRANQVYMIDFG 583 F+HRD+KPDN L+ ++ + + DFG Sbjct: 194 FIHRDVKPDNMLL---DKSGHLKLADFG 218
>CCRK_MACMU (Q5EDC3) Cell cycle-related kinase (EC 2.7.11.22)| (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) Length = 243 Score = 53.5 bits (127), Expect = 4e-07 Identities = 39/150 (26%), Positives = 71/150 (47%), Gaps = 4/150 (2%) Frame = +2 Query: 149 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK---LENVKTKHP-QLLYESKLYRVLQGG 316 ++Y + ++G G+ G ++ +V+T E VA+K L ++ P Q L E K + + Sbjct: 2 DQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMGDN 61 Query: 317 TGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSK 496 + +K G VL + + L ++ R L+ V ++ V F H+ Sbjct: 62 QYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHAN 121 Query: 497 SFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 + +HRD+KP N L+ + Q+ + DFGL Sbjct: 122 NIVHRDLKPANLLI---SASGQLKIADFGL 148
>DUN1_YEAST (P39009) DNA damage response protein kinase DUN1 (EC 2.7.11.1)| Length = 513 Score = 53.5 bits (127), Expect = 4e-07 Identities = 42/171 (24%), Positives = 83/171 (48%), Gaps = 25/171 (14%) Frame = +2 Query: 149 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKT-----KHPQLLYESKLYRVLQG 313 +KY LG++LG+G + + N +T ++VA+K+ + + K+ Q E+ + +Q Sbjct: 198 DKYLLGKELGAGHYALVKEAKNKKTGQQVAVKIFHAQQNDDQKKNKQFREETNILMRVQH 257 Query: 314 GTGISNVKWFGVEGDYNVLVMDVLGPSLED--LFSFCNRKLSLKT--VLMLADQMINRVE 481 ++ + F + + ++ ++D LF RK L+ L Q++ ++ Sbjct: 258 PNIVNLLDSFVEPISKSQIQKYLVLEKIDDGELFERIVRKTCLRQDESKALFKQLLTGLK 317 Query: 482 FIHSKSFLHRDIKPDNFLMGLGKRAN----------------QVYMIDFGL 586 ++H ++ +HRDIKP+N L+ + +R N QV + DFGL Sbjct: 318 YLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGL 368
>ICL1_KLULA (Q6CWQ4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 361 Score = 53.5 bits (127), Expect = 4e-07 Identities = 42/148 (28%), Positives = 71/148 (47%), Gaps = 5/148 (3%) Frame = +2 Query: 155 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRV--LQGGTGIS 328 + +G+ LG G FG++Y + +T A+K K + Q + + R +QG Sbjct: 100 FEIGKILGKGKFGKVYCVKHRETGLICALKAME-KKEIVQYTIQKQFRREVEIQGSFKHK 158 Query: 329 NV-KWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLM--LADQMINRVEFIHSKS 499 N+ + +G D + + + +L+ F L L QM N ++++HSK+ Sbjct: 159 NLTQLYGFFYDEKRVYLLMEYVYYGELYKFLKNNGPLNETLASYFVYQMANALDYMHSKN 218 Query: 500 FLHRDIKPDNFLMGLGKRANQVYMIDFG 583 LHRDIKP+N L+G N + + DFG Sbjct: 219 ILHRDIKPENILIGFN---NTIKLTDFG 243
>AFC3_ARATH (P51568) Serine/threonine-protein kinase AFC3 (EC 2.7.12.1)| Length = 400 Score = 53.5 bits (127), Expect = 4e-07 Identities = 40/138 (28%), Positives = 69/138 (50%), Gaps = 9/138 (6%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKL-ENVKTKHPQLLYE----SKLYRVLQGG 316 +Y++ K+G G+FG + + T E VAIK+ ++K + E KL + +G Sbjct: 70 RYKILSKMGEGTFGRVLECWDRDTKEYVAIKIIRSIKKYRDAAMIEIDVLQKLVKSDKGR 129 Query: 317 TGISNVK-WFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLAD---QMINRVEF 484 T +K WF ++ +V + LGPSL D K S + ++ D Q++ V + Sbjct: 130 TRCVQMKNWFDYR-NHICIVFEKLGPSLFDFLK--RNKYSAFPLALVRDFGCQLLESVAY 186 Query: 485 IHSKSFLHRDIKPDNFLM 538 +H +H D+KP+N L+ Sbjct: 187 MHELQLVHTDLKPENILL 204
>KPCD1_HUMAN (Q15139) Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1)| (Protein kinase D) (Protein kinase C mu type) (nPKC-mu) Length = 912 Score = 53.5 bits (127), Expect = 4e-07 Identities = 44/143 (30%), Positives = 71/143 (49%), Gaps = 6/143 (4%) Frame = +2 Query: 173 LGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHP-----QLLYESKLYRVLQGGTGISNVK 337 LGSG FG +Y G + +T +VAIK+ + K + P QL E + + L G+ N++ Sbjct: 589 LGSGQFGIVYGGKHRKTGRDVAIKIID-KLRFPTKQESQLRNEVAILQNLHH-PGVVNLE 646 Query: 338 WFGVEGDYNVLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRD 514 + +VM+ L G LE + S +L L Q++ + +H K+ +H D Sbjct: 647 CMFETPERVFVVMEKLHGDMLEMILSSEKGRLPEHITKFLITQILVALRHLHFKNIVHCD 706 Query: 515 IKPDNFLMGLGKRANQVYMIDFG 583 +KP+N L+ QV + DFG Sbjct: 707 LKPENVLLASADPFPQVKLCDFG 729
>MELK_HUMAN (Q14680) Maternal embryonic leucine zipper kinase (EC 2.7.11.1)| (hMELK) (Protein kinase PK38) (hPK38) Length = 651 Score = 53.5 bits (127), Expect = 4e-07 Identities = 43/153 (28%), Positives = 76/153 (49%), Gaps = 9/153 (5%) Frame = +2 Query: 155 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTGISNV 334 Y L +G+G F ++ L ++ T E VAIK+ + T S L R+ + N+ Sbjct: 11 YELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNT------LGSDLPRIKTEIEALKNL 64 Query: 335 KWFGVEGDYNVL-----VMDVL----GPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFI 487 + + Y+VL + VL G L D + +LS + ++ Q+++ V ++ Sbjct: 65 RHQHICQLYHVLETANKIFMVLEYCPGGELFD-YIISQDRLSEEETRVVFRQIVSAVAYV 123 Query: 488 HSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 HS+ + HRD+KP+N L +++ +IDFGL Sbjct: 124 HSQGYAHRDLKPENLLF---DEYHKLKLIDFGL 153
>PIM3_HUMAN (Q86V86) Serine/threonine-protein kinase Pim-3 (EC 2.7.11.1)| Length = 326 Score = 53.1 bits (126), Expect = 6e-07 Identities = 49/157 (31%), Positives = 75/157 (47%), Gaps = 14/157 (8%) Frame = +2 Query: 155 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQ--------LLYESKLYRVLQ 310 Y++G LGSG FG +Y G+ + VA+K VK + + + E L R + Sbjct: 40 YQVGAVLGSGGFGTVYAGSRIADGLPVAVK-HVVKERVTEWGSLGGATVPLEVVLLRKVG 98 Query: 311 GGTGISNV----KWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVL--MLADQMIN 472 G V WF D +LV++ P+ +DLF F + +L L Q++ Sbjct: 99 AAGGARGVIRLLDWF-ERPDGFLLVLERPEPA-QDLFDFITERGALDEPLARRFFAQVLA 156 Query: 473 RVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFG 583 V HS +HRDIK +N L+ L R+ ++ +IDFG Sbjct: 157 AVRHCHSCGVVHRDIKDENLLVDL--RSGELKLIDFG 191
>M3K2_HUMAN (Q9Y2U5) Mitogen-activated protein kinase kinase kinase 2 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2) Length = 619 Score = 53.1 bits (126), Expect = 6e-07 Identities = 43/162 (26%), Positives = 70/162 (43%), Gaps = 9/162 (5%) Frame = +2 Query: 125 PPMEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKL--- 295 P PR +RLG+ LG G+FG +YL +V T E+A+K P+ E Sbjct: 346 PSRSPRAPTNWRLGKLLGQGAFGRVYLCYDVDTGRELAVKQVQFDPDSPETSKEVNALEC 405 Query: 296 -YRVLQGGTGISNVKWFGV-----EGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLA 457 ++L+ V+++G E ++ + + G S++D L+ Sbjct: 406 EIQLLKNLLHERIVQYYGCLRDPQEKTLSIFMEYMPGGSIKDQLK-AYGALTENVTRKYT 464 Query: 458 DQMINRVEFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFG 583 Q++ V ++HS +HRDIK N L V + DFG Sbjct: 465 RQILEGVHYLHSNMIVHRDIKGANILR---DSTGNVKLGDFG 503
>KCC2D_HUMAN (Q13557) Calcium/calmodulin-dependent protein kinase type II delta| chain (EC 2.7.11.17) (CaM-kinase II delta chain) (CaM kinase II delta subunit) (CaMK-II delta subunit) Length = 499 Score = 53.1 bits (126), Expect = 6e-07 Identities = 41/155 (26%), Positives = 71/155 (45%), Gaps = 6/155 (3%) Frame = +2 Query: 140 RVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKT----KHPQLLYESKLYRVL 307 R ++Y+L +LG G+F + + T + A K+ N K H +L E+++ R+L Sbjct: 9 RFTDEYQLFEELGKGAFSVVRRCMKIPTGQGYAAKIINTKKLSARDHQKLEREARICRLL 68 Query: 308 QGGTGISNVKWFGVEGDYNVLVMDVL--GPSLEDLFSFCNRKLSLKTVLMLADQMINRVE 481 + + EG ++ LV D++ G ED+ + S Q++ V Sbjct: 69 KHPNIVRLHDSISEEG-FHYLVFDLVTGGELFEDIVA--REYYSEADASHCIQQILESVN 125 Query: 482 FIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 H +HRD+KP+N L+ + V + DFGL Sbjct: 126 HCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGL 160
>SPK1_CAEBR (Q61IS6) Serine/threonine-protein kinase spk-1 (EC 2.7.11.1)| Length = 771 Score = 53.1 bits (126), Expect = 6e-07 Identities = 42/148 (28%), Positives = 71/148 (47%), Gaps = 14/148 (9%) Frame = +2 Query: 149 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQL-LYESKLYRVLQGG--- 316 ++Y + RKLG G F ++L + Q A+K+ + + L E KL ++G Sbjct: 132 SRYHVIRKLGWGHFSTVWLAWDTQEKRFTAMKIVKSAEHYTEAALDEIKLLLSVRGADPE 191 Query: 317 -TGISNVKWF-------GVEGDYNVLVMDVLGPSLEDLFSFCN-RKLSLKTVLMLADQMI 469 TG V G+ G + +V +VLG +L L N R L L+ V + Q++ Sbjct: 192 DTGCHKVVQLLDEFTVTGINGQHVAMVFEVLGCNLLKLIIRSNYRGLHLEQVRKICKQIL 251 Query: 470 NRVEFIHSK-SFLHRDIKPDNFLMGLGK 550 + ++H K +H DIKP+N L+ + + Sbjct: 252 EALRYMHEKCGIIHTDIKPENVLITMSR 279
>AAPK1_HUMAN (Q13131) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 550 Score = 53.1 bits (126), Expect = 6e-07 Identities = 44/149 (29%), Positives = 74/149 (49%), Gaps = 5/149 (3%) Frame = +2 Query: 155 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTGISN- 331 Y LG LG G+FG++ +G + T +VA+K+ N + K L K+ R +Q + Sbjct: 18 YILGDTLGVGTFGKVKVGKHELTGHKVAVKILN-RQKIRSLDVVGKIRREIQNLKLFRHP 76 Query: 332 --VKWFGVEGDYNVLVMDVLGPSLEDLFSFC--NRKLSLKTVLMLADQMINRVEFIHSKS 499 +K + V + + M + S +LF + N +L K L Q+++ V++ H Sbjct: 77 HIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHM 136 Query: 500 FLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 +HRD+KP+N L+ A + DFGL Sbjct: 137 VVHRDLKPENVLLDAHMNAK---IADFGL 162
>LKH1_SCHPO (Q10156) Dual specificity protein kinase lkh1 (EC 2.7.12.1)| Length = 575 Score = 53.1 bits (126), Expect = 6e-07 Identities = 39/140 (27%), Positives = 66/140 (47%), Gaps = 7/140 (5%) Frame = +2 Query: 140 RVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQL-LYESKLYRVLQGG 316 + N+Y + R LG G+FG++ + T AIK+ K+ + L E ++ + + Sbjct: 242 KFANRYTVVRLLGHGTFGKVIQCYDQSTGRHCAIKVTRAIPKYREASLIELRVLQTIAHS 301 Query: 317 TGISNVKWFGVEG--DYN---VLVMDVLGPSLEDLFSFCNR-KLSLKTVLMLADQMINRV 478 + K + DY +V D+ G S+ D N LK + ML+ Q+ V Sbjct: 302 DPTNENKCIQLRDYFDYRKHICIVTDLFGWSVFDFLKNNNYIPFPLKHIQMLSQQLFKSV 361 Query: 479 EFIHSKSFLHRDIKPDNFLM 538 F+HS +H D+KP+N L+ Sbjct: 362 AFLHSLGLVHTDLKPENVLL 381
>AAPK1_RAT (P54645) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 548 Score = 53.1 bits (126), Expect = 6e-07 Identities = 44/149 (29%), Positives = 74/149 (49%), Gaps = 5/149 (3%) Frame = +2 Query: 155 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTGISN- 331 Y LG LG G+FG++ +G + T +VA+K+ N + K L K+ R +Q + Sbjct: 16 YILGDTLGVGTFGKVKVGKHELTGHKVAVKILN-RQKIRSLDVVGKIRREIQNLKLFRHP 74 Query: 332 --VKWFGVEGDYNVLVMDVLGPSLEDLFSFC--NRKLSLKTVLMLADQMINRVEFIHSKS 499 +K + V + + M + S +LF + N +L K L Q+++ V++ H Sbjct: 75 HIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHM 134 Query: 500 FLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 +HRD+KP+N L+ A + DFGL Sbjct: 135 VVHRDLKPENVLLDAHMNAK---IADFGL 160
>AAPK1_MOUSE (Q5EG47) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 548 Score = 53.1 bits (126), Expect = 6e-07 Identities = 44/149 (29%), Positives = 74/149 (49%), Gaps = 5/149 (3%) Frame = +2 Query: 155 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTGISN- 331 Y LG LG G+FG++ +G + T +VA+K+ N + K L K+ R +Q + Sbjct: 16 YILGDTLGVGTFGKVKVGKHELTGHKVAVKILN-RQKIRSLDVVGKIRREIQNLKLFRHP 74 Query: 332 --VKWFGVEGDYNVLVMDVLGPSLEDLFSFC--NRKLSLKTVLMLADQMINRVEFIHSKS 499 +K + V + + M + S +LF + N +L K L Q+++ V++ H Sbjct: 75 HIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHM 134 Query: 500 FLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 +HRD+KP+N L+ A + DFGL Sbjct: 135 VVHRDLKPENVLLDAHMNAK---IADFGL 160
>KCC2G_MOUSE (Q923T9) Calcium/calmodulin-dependent protein kinase type II gamma| chain (EC 2.7.11.17) (CaM-kinase II gamma chain) (CaM kinase II gamma subunit) (CaMK-II gamma subunit) Length = 529 Score = 52.8 bits (125), Expect = 7e-07 Identities = 42/155 (27%), Positives = 71/155 (45%), Gaps = 6/155 (3%) Frame = +2 Query: 140 RVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKT----KHPQLLYESKLYRVL 307 R + Y+L +LG G+F + + +E A K+ N K H +L E+++ R+L Sbjct: 9 RFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLL 68 Query: 308 QGGTGISNVKWFGVEGDYNVLVMDVL--GPSLEDLFSFCNRKLSLKTVLMLADQMINRVE 481 + + EG ++ LV D++ G ED+ + S Q++ V Sbjct: 69 KHPNIVRLHDSISEEG-FHYLVFDLVTGGELFEDIVA--REYYSEADASHCIHQILESVN 125 Query: 482 FIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 IH +HRD+KP+N L+ + V + DFGL Sbjct: 126 HIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGL 160
>ULK1_HUMAN (O75385) Serine/threonine-protein kinase ULK1 (EC 2.7.11.1)| (Unc-51-like kinase 1) Length = 1050 Score = 52.8 bits (125), Expect = 7e-07 Identities = 50/168 (29%), Positives = 79/168 (47%), Gaps = 17/168 (10%) Frame = +2 Query: 131 MEPRVGN-----KYRLGRK--LGSGSFGEIYLGTNVQTNE-EVAIKLENVKTKHPQLLYE 286 MEP G K+ RK +G G+F ++ G + + ++ EVA+K N K Sbjct: 1 MEPGRGGTETVGKFEFSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLL 60 Query: 287 SKLYRVLQGGTGISNVKWFGVEGDYN--VLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLA 457 K ++L+ + V + + N LVM+ G L D + R LS T+ + Sbjct: 61 GKEIKILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLAD-YLHAMRTLSEDTIRLFL 119 Query: 458 DQMINRVEFIHSKSFLHRDIKPDNFLMG--LGKRAN----QVYMIDFG 583 Q+ + +HSK +HRD+KP N L+ G+RAN +V + DFG Sbjct: 120 QQIAGAMRLLHSKGIIHRDLKPQNILLSNPAGRRANPNSIRVKIADFG 167
>KCC2G_HUMAN (Q13555) Calcium/calmodulin-dependent protein kinase type II gamma| chain (EC 2.7.11.17) (CaM-kinase II gamma chain) (CaM kinase II gamma subunit) (CaMK-II gamma subunit) Length = 558 Score = 52.8 bits (125), Expect = 7e-07 Identities = 42/155 (27%), Positives = 71/155 (45%), Gaps = 6/155 (3%) Frame = +2 Query: 140 RVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKT----KHPQLLYESKLYRVL 307 R + Y+L +LG G+F + + +E A K+ N K H +L E+++ R+L Sbjct: 9 RFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLL 68 Query: 308 QGGTGISNVKWFGVEGDYNVLVMDVL--GPSLEDLFSFCNRKLSLKTVLMLADQMINRVE 481 + + EG ++ LV D++ G ED+ + S Q++ V Sbjct: 69 KHPNIVRLHDSISEEG-FHYLVFDLVTGGELFEDIVA--REYYSEADASHCIHQILESVN 125 Query: 482 FIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 IH +HRD+KP+N L+ + V + DFGL Sbjct: 126 HIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGL 160
>KCC2G_RAT (P11730) Calcium/calmodulin-dependent protein kinase type II gamma| chain (EC 2.7.11.17) (CaM-kinase II gamma chain) (CaM kinase II gamma subunit) (CaMK-II gamma subunit) Length = 527 Score = 52.8 bits (125), Expect = 7e-07 Identities = 42/155 (27%), Positives = 71/155 (45%), Gaps = 6/155 (3%) Frame = +2 Query: 140 RVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKT----KHPQLLYESKLYRVL 307 R + Y+L +LG G+F + + +E A K+ N K H +L E+++ R+L Sbjct: 9 RFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLL 68 Query: 308 QGGTGISNVKWFGVEGDYNVLVMDVL--GPSLEDLFSFCNRKLSLKTVLMLADQMINRVE 481 + + EG ++ LV D++ G ED+ + S Q++ V Sbjct: 69 KHPNIVRLHDSISEEG-FHYLVFDLVTGGELFEDIVA--REYYSEADASHCIHQILESVN 125 Query: 482 FIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 IH +HRD+KP+N L+ + V + DFGL Sbjct: 126 HIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGL 160
>AFC2_ARATH (P51567) Serine/threonine-protein kinase AFC2 (EC 2.7.12.1)| Length = 427 Score = 52.8 bits (125), Expect = 7e-07 Identities = 37/136 (27%), Positives = 68/136 (50%), Gaps = 7/136 (5%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKL-ENVKTKHPQLLYESKLYRVL----QGG 316 +Y++ K+G G+FG++ + + E VA+K+ VK + E ++ + L +GG Sbjct: 97 RYKIYSKMGEGTFGQVLECWDRERKEMVAVKIVRGVKKYREAAMIEIEMLQQLGKHDKGG 156 Query: 317 TGISNVK-WFGVEGDYNVLVMDVLGPSLEDLFSFCN-RKLSLKTVLMLADQMINRVEFIH 490 ++ WF ++ +V + LG SL D N R + V + Q++ V F+H Sbjct: 157 NRCVQIRNWFDYR-NHICIVFEKLGSSLYDFLRKNNYRSFPIDLVREIGWQLLECVAFMH 215 Query: 491 SKSFLHRDIKPDNFLM 538 +H D+KP+N L+ Sbjct: 216 DLRMIHTDLKPENILL 231
>TLK2_MOUSE (O55047) Serine/threonine-protein kinase tousled-like 2 (EC| 2.7.11.1) (Tousled-like kinase 2) Length = 718 Score = 52.8 bits (125), Expect = 7e-07 Identities = 35/161 (21%), Positives = 73/161 (45%), Gaps = 11/161 (6%) Frame = +2 Query: 137 PRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKL---------ENVKTKHPQLLYES 289 P + ++Y L LG G F E+Y ++ VA+K+ E + H E Sbjct: 402 PTLNDRYLLLHLLGRGGFSEVYKAFDLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREY 461 Query: 290 KLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMI 469 ++++ L + +F ++ D V++ + D + ++ +S K + Q++ Sbjct: 462 RIHKELDHPRIVKLYDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQIV 521 Query: 470 NRVEFIHS--KSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 N +++++ +H D+KP N L+ G ++ + DFGL Sbjct: 522 NALKYLNEIKPPIIHYDLKPGNILLVNGTACGEIKITDFGL 562
>TLK2_HUMAN (Q86UE8) Serine/threonine-protein kinase tousled-like 2 (EC| 2.7.11.1) (Tousled-like kinase 2) (PKU-alpha) Length = 772 Score = 52.8 bits (125), Expect = 7e-07 Identities = 35/161 (21%), Positives = 73/161 (45%), Gaps = 11/161 (6%) Frame = +2 Query: 137 PRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKL---------ENVKTKHPQLLYES 289 P + ++Y L LG G F E+Y ++ VA+K+ E + H E Sbjct: 456 PTLNDRYLLLHLLGRGGFSEVYKAFDLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREY 515 Query: 290 KLYRVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMI 469 ++++ L + +F ++ D V++ + D + ++ +S K + Q++ Sbjct: 516 RIHKELDHPRIVKLYDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQIV 575 Query: 470 NRVEFIHS--KSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 N +++++ +H D+KP N L+ G ++ + DFGL Sbjct: 576 NALKYLNEIKPPIIHYDLKPGNILLVNGTACGEIKITDFGL 616
>MYLK_DICDI (P25323) Myosin light chain kinase (EC 2.7.11.18) (MLCK)| Length = 295 Score = 52.8 bits (125), Expect = 7e-07 Identities = 40/148 (27%), Positives = 67/148 (45%), Gaps = 4/148 (2%) Frame = +2 Query: 155 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENV----KTKHPQLLYESKLYRVLQGGTG 322 Y +LG G+F +YLG N QT + AIK+ N K L E + + + Sbjct: 8 YEFKEELGRGAFSIVYLGENKQTKQRYAIKVINKSELGKDYEKNLKMEVDILKKVNHPNI 67 Query: 323 ISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSF 502 I+ + F +++ V G L D S L ++++ V ++H + Sbjct: 68 IALKELFDTPEKLYLVMELVTGGELFDKIVE-KGSYSEADAANLVKKIVSAVGYLHGLNI 126 Query: 503 LHRDIKPDNFLMGLGKRANQVYMIDFGL 586 +HRD+KP+N L+ + +V + DFGL Sbjct: 127 VHRDLKPENLLLKSKENHLEVAIADFGL 154
>BYR2_SCHPO (P28829) Protein kinase byr2 (EC 2.7.11.25) (Protein kinase ste8)| (MAPK kinase kinase) (MAPKKK) Length = 659 Score = 52.8 bits (125), Expect = 7e-07 Identities = 46/155 (29%), Positives = 79/155 (50%), Gaps = 10/155 (6%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK---LENV---KTKHPQLLYE-SKLYRVLQ 310 K+ G +GSGSFG++YLG N + E +A+K L++V K +H +LL + +LQ Sbjct: 393 KWIRGALIGSGSFGQVYLGMNASSGELMAVKQVILDSVSESKDRHAKLLDALAGEIALLQ 452 Query: 311 GGTGISNVKWFG--VEGDY-NVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVE 481 + V++ G + D+ N+ + V G S+ L + V Q + +E Sbjct: 453 ELSHEHIVQYLGSNLNSDHLNIFLEYVPGGSVAGLLTMYG-SFEETLVKNFIKQTLKGLE 511 Query: 482 FIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 ++HS+ +HRDIK N L+ ++ + DFG+ Sbjct: 512 YLHSRGIVHRDIKGANILV---DNKGKIKISDFGI 543
>MARK2_HUMAN (Q7KZI7) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog) Length = 788 Score = 52.4 bits (124), Expect = 1e-06 Identities = 38/153 (24%), Positives = 76/153 (49%), Gaps = 3/153 (1%) Frame = +2 Query: 134 EPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVLQ 310 +P +GN YRL + +G G+F ++ L ++ T +EVA+K ++ + L + R+++ Sbjct: 47 QPHIGN-YRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMK 105 Query: 311 GGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSF--CNRKLSLKTVLMLADQMINRVEF 484 + VK F V L + + S ++F + + ++ K Q+++ V++ Sbjct: 106 VLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQY 165 Query: 485 IHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFG 583 H K +HRD+K +N L+ + + DFG Sbjct: 166 CHQKFIVHRDLKAENLLLDADM---NIKIADFG 195
>BRAF1_MOUSE (P28028) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Fragment) Length = 328 Score = 52.4 bits (124), Expect = 1e-06 Identities = 35/129 (27%), Positives = 63/129 (48%), Gaps = 3/129 (2%) Frame = +2 Query: 161 LGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTGISNVKW 340 +G+++GSGSFG +Y G + + +VA+K+ NV PQ L K + T N+ Sbjct: 21 VGQRIGSGSFGTVYKG---KWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILL 77 Query: 341 F---GVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHR 511 F + ++ G SL K + ++ +A Q ++++H+KS +HR Sbjct: 78 FMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHR 137 Query: 512 DIKPDNFLM 538 D+K +N + Sbjct: 138 DLKSNNIFL 146
>AAPK2_CAEEL (Q95ZQ4) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMP-activated kinase 2) Length = 626 Score = 52.4 bits (124), Expect = 1e-06 Identities = 43/149 (28%), Positives = 74/149 (49%), Gaps = 5/149 (3%) Frame = +2 Query: 155 YRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTGISN- 331 Y L LG G+FG++ +G + T +VA+K+ N + K L K+ R +Q + + Sbjct: 87 YILKETLGVGTFGKVKVGIHETTQYKVAVKILN-RQKIKSLDVVGKIRREIQNLSLFRHP 145 Query: 332 --VKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTV--LMLADQMINRVEFIHSKS 499 ++ + V + + M + S +LF + + LKT Q+I+ V++ H Sbjct: 146 HIIRLYQVISTPSDIFMIMEHVSGGELFDYIVKHGRLKTAEARRFFQQIISGVDYCHRHM 205 Query: 500 FLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 +HRD+KP+N L+ N V + DFGL Sbjct: 206 VVHRDLKPENLLL---DEQNNVKIADFGL 231
>RMIL_AVEVR (P27966) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 450 Score = 52.4 bits (124), Expect = 1e-06 Identities = 35/129 (27%), Positives = 63/129 (48%), Gaps = 3/129 (2%) Frame = +2 Query: 161 LGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTGISNVKW 340 +G+++GSGSFG +Y G + + +VA+K+ NV PQ L K + T N+ Sbjct: 85 VGQRIGSGSFGTVYKG---KWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILL 141 Query: 341 F---GVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHR 511 F + ++ G SL K + ++ +A Q ++++H+KS +HR Sbjct: 142 FMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHR 201 Query: 512 DIKPDNFLM 538 D+K +N + Sbjct: 202 DLKSNNIFL 210
>RIPK5_CHICK (Q6XUX0) Receptor-interacting serine/threonine-protein kinase 5 (EC| 2.7.11.1) (Dusty protein kinase) (Dusty PK) Length = 930 Score = 52.4 bits (124), Expect = 1e-06 Identities = 41/141 (29%), Positives = 69/141 (48%), Gaps = 6/141 (4%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKH-PQLLYESKLYRVLQGGTGI 325 K +LGR+LG G +G +YL + + A+K + KH L E R LQ + Sbjct: 652 KPKLGRELGRGQYGVVYLCDSWGGHFPCALKSVVPPDEKHWNDLALEFHYMRSLQSHERL 711 Query: 326 ----SNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHS 493 +V +G G ++ V+ ++ DL++ L L+T L +A ++ + ++HS Sbjct: 712 VDLHGSVIDYGYGGGSSIAVLLIMERLHRDLYTGLKAGLELETRLQIALDVVEGIRYLHS 771 Query: 494 KSFLHRDIKPDNFLMGLGKRA 556 + +HRDIK N L+ RA Sbjct: 772 QGLVHRDIKLKNVLLDKKNRA 792
>STK36_MOUSE (Q69ZM6) Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused| homolog) Length = 1268 Score = 52.4 bits (124), Expect = 1e-06 Identities = 45/154 (29%), Positives = 67/154 (43%), Gaps = 10/154 (6%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTGISN 331 KY + +G GSFG +Y G + + VA+K P+L K R LQ I Sbjct: 3 KYHVLEMIGEGSFGRVYKGRKKYSAQVVALKFI------PKLGRSEKELRNLQREIEIMR 56 Query: 332 VKWF--------GVEGDYNVLVMDVLGPSLEDLFSFC--NRKLSLKTVLMLADQMINRVE 481 W E D V+V+ +LF + KL V +A Q+++ + Sbjct: 57 GLWHPNIVHMLDSFETDKEVVVVTDYAEG--ELFQILEDDGKLPEDQVQAIAAQLVSALY 114 Query: 482 FIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFG 583 ++HS LHRD+KP N L+ G + + DFG Sbjct: 115 YLHSHRILHRDMKPQNILLAKG---GGIKLCDFG 145
>MARK2_RAT (O08679) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1) Length = 722 Score = 52.4 bits (124), Expect = 1e-06 Identities = 38/153 (24%), Positives = 76/153 (49%), Gaps = 3/153 (1%) Frame = +2 Query: 134 EPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVLQ 310 +P +GN YRL + +G G+F ++ L ++ T +EVA+K ++ + L + R+++ Sbjct: 47 QPHIGN-YRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMK 105 Query: 311 GGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSF--CNRKLSLKTVLMLADQMINRVEF 484 + VK F V L + + S ++F + + ++ K Q+++ V++ Sbjct: 106 VLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQY 165 Query: 485 IHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFG 583 H K +HRD+K +N L+ + + DFG Sbjct: 166 CHQKFIVHRDLKAENLLLDADM---NIKIADFG 195
>CDC2H_DICDI (P34117) CDC2-like serine/threonine-protein kinase CRP (EC| 2.7.11.22) (EC 2.7.11.23) Length = 292 Score = 52.4 bits (124), Expect = 1e-06 Identities = 41/149 (27%), Positives = 66/149 (44%), Gaps = 4/149 (2%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQL----LYESKLYRVLQGGT 319 KY KLG G++G + N +T E VA+K + ++ + + E L + L+ Sbjct: 3 KYSKIEKLGEGTYGIVNKAKNRETGEIVALKRIRLDSEDEGVPCTAIREISLLKELKHPN 62 Query: 320 GISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKS 499 + E LV + L L+ C ++S T+ Q++ V F H Sbjct: 63 IVRLHDVIHTERKLT-LVFEYLDQDLKKYLDECGGEISKPTIKSFMYQLLKGVAFCHDHR 121 Query: 500 FLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 LHRD+KP N L+ R ++ + DFGL Sbjct: 122 VLHRDLKPQNLLI---NRKGELKLADFGL 147
>BRAF1_HUMAN (P15056) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1) Length = 766 Score = 52.4 bits (124), Expect = 1e-06 Identities = 35/129 (27%), Positives = 63/129 (48%), Gaps = 3/129 (2%) Frame = +2 Query: 161 LGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTGISNVKW 340 +G+++GSGSFG +Y G + + +VA+K+ NV PQ L K + T N+ Sbjct: 459 VGQRIGSGSFGTVYKG---KWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILL 515 Query: 341 F---GVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHR 511 F + ++ G SL K + ++ +A Q ++++H+KS +HR Sbjct: 516 FMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHR 575 Query: 512 DIKPDNFLM 538 D+K +N + Sbjct: 576 DLKSNNIFL 584
>TAOK3_CHICK (Q9I9E0) Serine/threonine-protein kinase TAO3 (EC 2.7.11.1)| (Thousand and one amino acid protein 3) (Kinase from chicken) Length = 898 Score = 52.4 bits (124), Expect = 1e-06 Identities = 40/143 (27%), Positives = 63/143 (44%), Gaps = 5/143 (3%) Frame = +2 Query: 170 KLGSGSFGEIYLGTNVQTNEEVAIKL-----ENVKTKHPQLLYESKLYRVLQGGTGISNV 334 ++G GSFG +Y TN TNE VA+K + K ++ E K + L+ I Sbjct: 29 EIGHGSFGAVYFATNSHTNEVVAVKKMSYSGKQTNEKWQDIIKEVKFLQQLKHPNTI-EY 87 Query: 335 KWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHRD 514 K ++ LVM+ S D+ + L + + + + ++HS +HRD Sbjct: 88 KGCYLKEHTAWLVMEYCLGSASDMLEVHKKPLQEVEIAAITHGALQGLAYLHSHCKIHRD 147 Query: 515 IKPDNFLMGLGKRANQVYMIDFG 583 IK N L+ QV + DFG Sbjct: 148 IKAGNILL---TEPGQVKLADFG 167
>RMIL_AVII1 (P10533) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 367 Score = 52.4 bits (124), Expect = 1e-06 Identities = 35/129 (27%), Positives = 63/129 (48%), Gaps = 3/129 (2%) Frame = +2 Query: 161 LGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTGISNVKW 340 +G+++GSGSFG +Y G + + +VA+K+ NV PQ L K + T N+ Sbjct: 69 VGQRIGSGSFGTVYKG---KWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILL 125 Query: 341 F---GVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHR 511 F + ++ G SL K + ++ +A Q ++++H+KS +HR Sbjct: 126 FMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHR 185 Query: 512 DIKPDNFLM 538 D+K +N + Sbjct: 186 DLKSNNIFL 194
>PASK_MOUSE (Q8CEE6) PAS domain-containing serine/threonine-protein kinase (EC| 2.7.11.1) (PAS-kinase) (PASKIN) Length = 1383 Score = 52.4 bits (124), Expect = 1e-06 Identities = 43/155 (27%), Positives = 74/155 (47%), Gaps = 11/155 (7%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK-LENVKTKHPQLLYESKLYRVLQGGTGIS 328 KY LGSG+FG ++ + N+EV +K ++ K + + KL RV +S Sbjct: 1058 KYNTISPLGSGAFGFVWTAVEKECNKEVVVKFIKKEKVLEDCWIEDPKLGRVTLEIAILS 1117 Query: 329 NVKWFGV--------EGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVL--MLADQMINRV 478 V + ++ LVM+ G + DLF+F + L L + Q+++ V Sbjct: 1118 KVDHANIIKVLDIFENQEFFQLVMEKHGSGM-DLFAFIDHHPCLDEPLASFIFRQLVSAV 1176 Query: 479 EFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFG 583 ++HS+ +HRDIK +N ++ + +IDFG Sbjct: 1177 GYLHSQGIIHRDIKDENIVIA---EDFTIKLIDFG 1208
>CHK2_MOUSE (Q9Z265) Serine/threonine-protein kinase Chk2 (EC 2.7.11.1)| Length = 546 Score = 52.4 bits (124), Expect = 1e-06 Identities = 39/155 (25%), Positives = 73/155 (47%), Gaps = 10/155 (6%) Frame = +2 Query: 149 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKT----------KHPQLLYESKLY 298 ++Y + + LGSG+ GE+ + +T ++VAIK+ + + P + E ++ Sbjct: 222 DEYIMSKTLGSGACGEVKMAFERKTCQKVAIKIISKRRFALGSSREADTAPSVETEIEIL 281 Query: 299 RVLQGGTGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRV 478 + L I F E Y VL + G + + N++L T + QM+ V Sbjct: 282 KKLNHPCIIKIKDVFDAEDYYIVLELMEGGELFDRVVG--NKRLKEATCKLYFYQMLVAV 339 Query: 479 EFIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFG 583 +++H +HRD+KP+N L+ + + + DFG Sbjct: 340 QYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFG 374
>BRAF1_COTJA (P34908) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (RMIL serine/threonine-protein kinase) (c-RMIL) Length = 807 Score = 52.4 bits (124), Expect = 1e-06 Identities = 35/129 (27%), Positives = 63/129 (48%), Gaps = 3/129 (2%) Frame = +2 Query: 161 LGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTGISNVKW 340 +G+++GSGSFG +Y G + + +VA+K+ NV PQ L K + T N+ Sbjct: 499 VGQRIGSGSFGTVYKG---KWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILL 555 Query: 341 F---GVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHR 511 F + ++ G SL K + ++ +A Q ++++H+KS +HR Sbjct: 556 FMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHR 615 Query: 512 DIKPDNFLM 538 D+K +N + Sbjct: 616 DLKSNNIFL 624
>SID1_SCHPO (O14305) Serine/threonine-protein kinase sid1 (EC 2.7.11.1)| (STE20-like kinase sid1) Length = 471 Score = 52.4 bits (124), Expect = 1e-06 Identities = 40/155 (25%), Positives = 79/155 (50%), Gaps = 3/155 (1%) Frame = +2 Query: 131 MEPRVGNKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQ 310 M P N Y L RKLGSGSFG ++ + + +AIK +++T + + +L Sbjct: 1 MYPLNANSYTLLRKLGSGSFGVVWKARENVSGDIIAIKQIDLETGIDDITDIEQEVFMLS 60 Query: 311 GGTGISNVKWFG--VEGDYNVLVMDVL-GPSLEDLFSFCNRKLSLKTVLMLADQMINRVE 481 + ++++G V+G ++M+ + G S+ L +L+ + + ++ +++ + Sbjct: 61 NCNSSNVIQYYGCFVDGYTLWILMEHMDGGSVSGLLKM--GRLNEQVISIILREVLYGLN 118 Query: 482 FIHSKSFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 ++H ++ +HRDIK N L L V + DFG+ Sbjct: 119 YLHGQNKIHRDIKAANIL--LSSSTGNVKLADFGV 151
>BRAF1_CHICK (Q04982) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Rmil serine/threonine-protein kinase) (c-Rmil) Length = 806 Score = 52.4 bits (124), Expect = 1e-06 Identities = 35/129 (27%), Positives = 63/129 (48%), Gaps = 3/129 (2%) Frame = +2 Query: 161 LGRKLGSGSFGEIYLGTNVQTNEEVAIKLENVKTKHPQLLYESKLYRVLQGGTGISNVKW 340 +G+++GSGSFG +Y G + + +VA+K+ NV PQ L K + T N+ Sbjct: 499 VGQRIGSGSFGTVYKG---KWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILL 555 Query: 341 F---GVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKSFLHR 511 F + ++ G SL K + ++ +A Q ++++H+KS +HR Sbjct: 556 FMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHR 615 Query: 512 DIKPDNFLM 538 D+K +N + Sbjct: 616 DLKSNNIFL 624
>STK36_PONPY (Q5RAJ5) Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused| homolog) Length = 1315 Score = 52.0 bits (123), Expect = 1e-06 Identities = 41/148 (27%), Positives = 70/148 (47%), Gaps = 4/148 (2%) Frame = +2 Query: 152 KYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK----LENVKTKHPQLLYESKLYRVLQGGT 319 KY + +G GSFG +Y G + + VA+K L + + L E ++ R L+ Sbjct: 3 KYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRHPN 62 Query: 320 GISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSKS 499 + + F + + V+ G L+ L + KL V +A Q+++ + ++HS Sbjct: 63 IVHMLDSFETDKEVVVVTDYAEGELLQILED--DGKLPEDQVQAIAAQLVSALYYLHSHR 120 Query: 500 FLHRDIKPDNFLMGLGKRANQVYMIDFG 583 LHRD+KP N L+ G + + DFG Sbjct: 121 ILHRDMKPQNILLAKG---GGIKLCDFG 145
>CCRK_PONPY (Q5R7I7) Cell cycle-related kinase (EC 2.7.11.22)| Length = 346 Score = 52.0 bits (123), Expect = 1e-06 Identities = 38/150 (25%), Positives = 71/150 (47%), Gaps = 4/150 (2%) Frame = +2 Query: 149 NKYRLGRKLGSGSFGEIYLGTNVQTNEEVAIK---LENVKTKHP-QLLYESKLYRVLQGG 316 ++Y + ++G G+ G ++ +V+T E VA+K L ++ P Q L E K + ++ Sbjct: 2 DQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQALREIKALQEMEDN 61 Query: 317 TGISNVKWFGVEGDYNVLVMDVLGPSLEDLFSFCNRKLSLKTVLMLADQMINRVEFIHSK 496 + +K VL + + L ++ R L+ V ++ V F H+ Sbjct: 62 QYVVQLKAVFPHSAGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVSFCHAN 121 Query: 497 SFLHRDIKPDNFLMGLGKRANQVYMIDFGL 586 + +HRD+KP N L+ + Q+ + DFGL Sbjct: 122 NIVHRDLKPANLLI---SASGQLKIADFGL 148 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 76,026,165 Number of Sequences: 219361 Number of extensions: 1399178 Number of successful extensions: 7442 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 6047 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6505 length of database: 80,573,946 effective HSP length: 106 effective length of database: 57,321,680 effective search space used: 5101629520 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
