Clone Information

BLAST Search Result

Clone Name	baal23a21
Clone Library Name	barley_pub

No.	Definition	Score (bits)	E Value
1	AFR_ARATH (Q8LAW2) Protein AFR (Protein ATTENUATED FAR-RED RESPO...	65	1e-10
2	KLHL2_MOUSE (Q8JZP3) Kelch-like protein 2	65	2e-10
3	KLHL2_HUMAN (O95198) Kelch-like protein 2 (Actin-binding protein...	65	2e-10
4	IPP_MOUSE (P28575) Actin-binding protein IPP (MIPP protein) (Mur...	61	3e-09
5	KLH18_HUMAN (O94889) Kelch-like protein 18	60	7e-09
6	IPP_HUMAN (Q9Y573) Actin-binding protein IPP (MIPP protein)	60	7e-09
7	KLH20_MOUSE (Q8VCK5) Kelch-like protein 20 (Kelch-like ECT2-inte...	59	9e-09
8	KLH20_HUMAN (Q9Y2M5) Kelch-like protein 20 (Kelch-like ECT2-inte...	59	9e-09
9	ENC1_MOUSE (O35709) Ectoderm-neural cortex 1 protein (ENC-1)	59	1e-08
10	ENC1_HUMAN (O14682) Ectoderm-neural cortex 1 protein (ENC-1) (p5...	58	2e-08
11	KLHL3_HUMAN (Q9UH77) Kelch-like protein 3	56	9e-08
12	KELC_ANOST (Q70JS2) Ring canal kelch homolog (Kelch-like protein...	56	9e-08
13	KLDC5_HUMAN (Q9P2K6) Kelch domain-containing protein 5	55	1e-07
14	KLHL5_HUMAN (Q96PQ7) Kelch-like protein 5	55	2e-07
15	KEAP1_HUMAN (Q14145) Kelch-like ECH-associated protein 1 (Cytoso...	55	2e-07
16	KLDC5_MOUSE (Q8BFQ9) Kelch domain-containing protein 5	55	2e-07
17	KLHL4_HUMAN (Q9C0H6) Kelch-like protein 4	55	2e-07
18	KELC_DROME (Q04652) Ring canal kelch protein [Contains: Kelch sh...	55	2e-07
19	GAN_HUMAN (Q9H2C0) Gigaxonin (Kelch-like protein 16)	54	4e-07
20	KLHL1_HUMAN (Q9NR64) Kelch-like protein 1	54	4e-07
21	KLHL1_MOUSE (Q9JI74) Kelch-like protein 1	54	4e-07
22	KLH14_CHICK (Q5F3N5) Kelch-like protein 14	54	5e-07
23	KLD7B_HUMAN (Q96G42) Kelch domain-containing protein 7B	54	5e-07
24	KEAP1_MOUSE (Q9Z2X8) Kelch-like ECH-associated protein 1 (Cytoso...	54	5e-07
25	KLH14_HUMAN (Q9P2G3) Kelch-like protein 14	54	5e-07
26	KEAP1_RAT (P57790) Kelch-like ECH-associated protein 1 (Cytosoli...	52	1e-06
27	KLHL7_CHICK (Q5ZI33) Kelch-like protein 7	50	5e-06
28	KLHL8_MOUSE (P59280) Kelch-like protein 8	49	1e-05
29	KLHL7_RAT (Q5XHZ6) Kelch-like protein 7	49	1e-05
30	KLHL7_MOUSE (Q8BUL5) Kelch-like protein 7	49	1e-05
31	KLHL7_HUMAN (Q8IXQ5) Kelch-like protein 7	49	1e-05
32	KBTBB_MOUSE (Q8BNW9) Kelch repeat and BTB domain-containing prot...	49	2e-05
33	KBTBB_HUMAN (O94819) Kelch repeat and BTB domain-containing prot...	49	2e-05
34	KLHL8_HUMAN (Q9P2G9) Kelch-like protein 8	48	2e-05
35	BTBD5_MOUSE (Q9CR40) BTB/POZ domain-containing protein 5	48	3e-05
36	KBTBA_RAT (Q9ER30) Kelch repeat and BTB domain-containing protei...	48	3e-05
37	KLH12_XENLA (Q6NRH0) Kelch-like protein 12	47	3e-05
38	BTBD5_HUMAN (Q9NXS3) BTB/POZ domain-containing protein 5	47	3e-05
39	KLH12_BRARE (Q5U374) Kelch-like protein 12	47	4e-05
40	KLH12_RAT (Q8R2H4) Kelch-like protein 12 (CUL3-interacting prote...	47	6e-05
41	KLH12_MOUSE (Q8BZM0) Kelch-like protein 12 (CUL3-interacting pro...	47	6e-05
42	KLH12_HUMAN (Q53G59) Kelch-like protein 12 (CUL3-interacting pro...	47	6e-05
43	KLH10_RAT (Q6JEL3) Kelch-like protein 10	46	7e-05
44	KLH10_MOUSE (Q9D5V2) Kelch-like protein 10	46	7e-05
45	KLH17_RAT (Q8K430) Kelch-like protein 17 (Actinfilin)	46	7e-05
46	KLH17_MOUSE (Q6TDP3) Kelch-like protein 17 (Actinfilin)	46	7e-05
47	KLH17_HUMAN (Q6TDP4) Kelch-like protein 17 (Actinfilin)	46	1e-04
48	KLH21_HUMAN (Q9UJP4) Kelch-like protein 21	46	1e-04
49	KLH10_HUMAN (Q6JEL2) Kelch-like protein 10	46	1e-04
50	VMT9_MYXVL (P08073) Kelch repeat protein M-T9 (M9-R polypeptide)	44	4e-04
51	KBTB7_HUMAN (Q8WVZ9) Kelch repeat and BTB domain-containing prot...	43	8e-04
52	KBTB6_HUMAN (Q86V97) Kelch repeat and BTB domain-containing prot...	43	8e-04
53	KLH13_MOUSE (Q80TF4) Kelch-like protein 13 (BTB and kelch domain...	42	0.001
54	BKLH5_HUMAN (Q96NJ5) BTB and kelch domain-containing protein 5	42	0.001
55	KLHL6_MOUSE (Q6V595) Kelch-like protein 6	42	0.001
56	KLHL6_HUMAN (Q8WZ60) Kelch-like protein 6	42	0.001
57	KLH13_HUMAN (Q9P2N7) Kelch-like protein 13 (BTB and kelch domain...	41	0.002
58	KBTBA_HUMAN (O60662) Kelch repeat and BTB domain-containing prot...	41	0.003
59	VC04_SWPVK (P32228) Protein C4	41	0.003
60	SCRA_LIMPO (Q25390) Alpha-scruin	41	0.003
61	KLD8A_MOUSE (Q91XA8) Kelch domain-containing protein 8A	41	0.003
62	KHL15_BRARE (Q6DEL7) Kelch-like protein 15	40	0.004
63	KLHL9_MOUSE (Q6ZPT1) Kelch-like protein 9	40	0.004
64	KLHL9_HUMAN (Q9P2J3) Kelch-like protein 9	40	0.004
65	VMT8_MYXVL (P22611) Kelch repeat protein M-T8	40	0.004
66	KBTB9_MOUSE (Q80T74) Kelch repeat and BTB domain-containing prot...	39	0.009
67	KBTB9_HUMAN (Q96CT2) Kelch repeat and BTB domain-containing prot...	39	0.009
68	VA55_VACCV (P24768) Kelch repeat protein A55	39	0.009
69	VA55_VACCC (P21073) Kelch repeat protein A55	39	0.009
70	SCRB_LIMPO (Q25386) Beta-scruin	39	0.012
71	VC13_SWPVK (P32206) Protein C13	38	0.027
72	KHL15_HUMAN (Q96M94) Kelch-like protein 15	37	0.045
73	KLDC3_RAT (Q6AYI2) Kelch domain-containing protein 3	37	0.045
74	KLDC3_MOUSE (Q8VEM9) Kelch domain-containing protein 3 (Protein ...	37	0.045
75	VC02_VACCV (P17371) Kelch repeat protein C2	35	0.17
76	VC02_VACCT (Q9JFG1) Kelch repeat protein C2	35	0.17
77	VC02_VACCC (P21037) Kelch repeat protein C2	35	0.17
78	VC02_RABPU (Q6RZS3) Kelch repeat protein C2	35	0.17
79	VC02_CWPXG (P87617) Kelch repeat protein C2	35	0.17
80	VC02_CAMPS (Q776A6) Kelch repeat protein C2	35	0.17
81	VC02_CAMPM (Q8V2Z3) Kelch repeat protein C2	35	0.17
82	KLDC3_HUMAN (Q9BQ90) Kelch domain-containing protein 3 (Protein ...	35	0.17
83	SPE26_CAEEL (Q10579) Spermatocyte protein spe-26	35	0.23
84	KBTB3_MOUSE (Q8BHI4) Kelch repeat and BTB domain-containing prot...	34	0.38
85	VC02_ECTVM (Q8JLI4) Kelch repeat protein C2	33	0.50
86	KEL10_CAEEL (P34569) Kelch repeat-containing protein kel-10	33	0.86
87	VF03_VACCV (P24357) Kelch repeat protein F3	32	1.1
88	VF03_VACCC (P21013) Kelch repeat protein F3	32	1.1
89	VF03_VACCA (O57174) Kelch repeat protein F3	32	1.1
90	KLD8A_HUMAN (Q8IYD2) Kelch domain-containing protein 8A	32	1.5
91	KEL2_YEAST (P50090) Kelch repeat-containing protein 2	32	1.9
92	Y939_SULTO (Q973G3) Hypothetical protein ST0939 precursor	32	1.9
93	XERC_SHEON (Q7ZAJ5) Tyrosine recombinase xerC	32	1.9
94	VB10_VACCV (Q76ZL3) Kelch repeat protein B10	31	2.5
95	VB10_VACCT (Q77TF6) Kelch repeat protein B10	31	2.5
96	VB10_VACCC (P68687) Kelch repeat protein B10	31	2.5
97	VB10_RABPU (Q6RZB9) Kelch repeat protein B10	31	2.5
98	KLD8B_RAT (Q5XIA9) Kelch domain-containing protein 8B	31	2.5
99	VB10_VACCA (O57257) Kelch repeat protein B10	31	2.5
100	YT73_CAEEL (Q11087) Hypothetical protein C01C10.3	31	3.3
101	NDUB4_MOUSE (Q9CQC7) NADH dehydrogenase [ubiquinone] 1 beta subc...	31	3.3
102	KBTB2_HUMAN (Q8IY47) Kelch repeat and BTB domain-containing prot...	31	3.3
103	LCMT2_HUMAN (O60294) Leucine carboxyl methyltransferase 2 (EC 2....	30	4.2
104	CALI_HUMAN (Q13939) Calicin	30	4.2
105	CD34_MOUSE (Q64314) Hematopoietic progenitor cell antigen CD34 p...	30	5.6
106	TEA3_SCHPO (O14248) Tip elongation aberrant protein 3 (Cell pola...	30	7.2

>AFR_ARATH (Q8LAW2) Protein AFR (Protein ATTENUATED FAR-RED RESPONSE)|
          Length = 372

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 41/178 (23%), Positives = 77/178 (43%), Gaps = 5/178 (2%)
 Frame = +2

Query: 86  CLMRVSRAEHPNLRLVCRKWSRLLSGNYYYSLRKKFGMAEEWVYVFKRDRDQ-KLSWHAF 262
           CL+R+    H   R V   W++ ++   +   ++   ++  +++VF  ++   ++ W + 
Sbjct: 40  CLLRLPYPYHALYRSVSSSWNKTITNPRFLFSKQSLSISSPYLFVFAFNKSTARIQWQSL 99

Query: 263 DPVHQLWRSLPPVPPEY---SEAVGFGCAVLSGC-YLYLFGGKDPVRGSMRHVVFYNTRT 430
           D     W  LPP+P  +   S      CA +     L++ GG D  R +    V Y   T
Sbjct: 100 DLASGRWFVLPPMPNSFTKISSPHALSCASMPRQGKLFVLGGGDVNRSA----VVYTALT 155

Query: 431 NKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEM 604
           N+W     M+  R  F S  +N  +   GG   G        E Y+P+ + W+ + ++
Sbjct: 156 NRWSCISPMMSPRTYFVSGNVNGKIMAVGGSVGGNGEATTEVESYDPDNDTWTVVKKL 213

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>KLHL2_MOUSE (Q8JZP3) Kelch-like protein 2|
          Length = 593

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 40/118 (33%), Positives = 58/118 (49%)
 Frame = +2

Query: 257 AFDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNK 436
           ++DPV   W S+  +    S     G AVL+G  LY  GG D   G +  V  YN ++N+
Sbjct: 372 SYDPVKDQWTSVANMRDRRST---LGAAVLNGL-LYAVGGFDGSTG-LSSVEAYNIKSNE 426

Query: 437 WYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMNT 610
           W+    M  +R   G  V+   LY  GG     ++ L + E YN   N W+ I+EM+T
Sbjct: 427 WFHVAPMNTRRSSVGVGVVGGLLYAVGGYDGASRQCLSTVECYNATANEWTYIAEMST 484



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 40/99 (40%), Positives = 51/99 (51%), Gaps = 3/99 (3%)
 Frame = +2

Query: 326 GFGCAVLSGCYLYLFGGKDP--VRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINN 499
           G G  VL+   LY  GG D   VR S   V  Y+  TN W +  DM   R   G C +N 
Sbjct: 488 GAGVGVLNNL-LYAVGGHDGPLVRKS---VEVYDPTTNAWRQVADMNMCRRNAGVCAVNG 543

Query: 500 CLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISE-MNTG 613
            LYV GG+ +G    L S E YNP  ++W+ +S  M+TG
Sbjct: 544 LLYVVGGD-DG-SCNLASVEYYNPTTDKWTVVSSCMSTG 580



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 36/104 (34%), Positives = 49/104 (47%), Gaps = 1/104 (0%)
 Frame = +2

Query: 299 VPPEYSEAVGFGCAVLSGCYLYLFGGKDPV-RGSMRHVVFYNTRTNKWYRAPDMLRKRHL 475
           V P  +     G  V+ G  LY  GG D   R  +  V  YN   N+W    +M  +R  
Sbjct: 430 VAPMNTRRSSVGVGVVGGL-LYAVGGYDGASRQCLSTVECYNATANEWTYIAEMSTRRSG 488

Query: 476 FGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMN 607
            G  V+NN LY  GG    + R  +S EVY+P  N W  +++MN
Sbjct: 489 AGVGVLNNLLYAVGGHDGPLVR--KSVEVYDPTTNAWRQVADMN 530



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 33/121 (27%), Positives = 52/121 (42%)
 Frame = +2

Query: 248 SWHAFDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTR 427
           S   +D   + W  +  +P     A   G   ++G    + G    +R  +R V  Y+  
Sbjct: 322 SVECYDFKEERWHQVAELPSRRCRA---GMVYMAGLVFAVGGFNGSLR--VRTVDSYDPV 376

Query: 428 TNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMN 607
            ++W    +M  +R   G+ V+N  LY  GG  +G    L S E YN   N W  ++ MN
Sbjct: 377 KDQWTSVANMRDRRSTLGAAVLNGLLYAVGG-FDG-STGLSSVEAYNIKSNEWFHVAPMN 434

Query: 608 T 610
           T
Sbjct: 435 T 435



 Score = 33.1 bits (74), Expect = 0.66
 Identities = 16/82 (19%), Positives = 44/82 (53%)
 Frame = +2

Query: 359 LYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQ 538
           + + GG+ P   ++R V  Y+ +  +W++  ++  +R   G   +   ++  GG    ++
Sbjct: 309 MVVVGGQAPK--AIRSVECYDFKEERWHQVAELPSRRCRAGMVYMAGLVFAVGGFNGSLR 366

Query: 539 RTLRSAEVYNPNRNRWSCISEM 604
             +R+ + Y+P +++W+ ++ M
Sbjct: 367 --VRTVDSYDPVKDQWTSVANM 386

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>KLHL2_HUMAN (O95198) Kelch-like protein 2 (Actin-binding protein Mayven)|
          Length = 593

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 40/118 (33%), Positives = 58/118 (49%)
 Frame = +2

Query: 257 AFDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNK 436
           ++DPV   W S+  +    S     G AVL+G  LY  GG D   G +  V  YN ++N+
Sbjct: 372 SYDPVKDQWTSVANMRDRRST---LGAAVLNGL-LYAVGGFDGSTG-LSSVEAYNIKSNE 426

Query: 437 WYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMNT 610
           W+    M  +R   G  V+   LY  GG     ++ L + E YN   N W+ I+EM+T
Sbjct: 427 WFHVAPMNTRRSSVGVGVVGGLLYAVGGYDGASRQCLSTVECYNATTNEWTYIAEMST 484



 Score = 56.6 bits (135), Expect = 6e-08
 Identities = 37/104 (35%), Positives = 50/104 (48%), Gaps = 1/104 (0%)
 Frame = +2

Query: 299 VPPEYSEAVGFGCAVLSGCYLYLFGGKDPV-RGSMRHVVFYNTRTNKWYRAPDMLRKRHL 475
           V P  +     G  V+ G  LY  GG D   R  +  V  YN  TN+W    +M  +R  
Sbjct: 430 VAPMNTRRSSVGVGVVGGL-LYAVGGYDGASRQCLSTVECYNATTNEWTYIAEMSTRRSG 488

Query: 476 FGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMN 607
            G  V+NN LY  GG    + R  +S EVY+P  N W  +++MN
Sbjct: 489 AGVGVLNNLLYAVGGHDGPLVR--KSVEVYDPTTNAWRQVADMN 530



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 40/99 (40%), Positives = 51/99 (51%), Gaps = 3/99 (3%)
 Frame = +2

Query: 326 GFGCAVLSGCYLYLFGGKDP--VRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINN 499
           G G  VL+   LY  GG D   VR S   V  Y+  TN W +  DM   R   G C +N 
Sbjct: 488 GAGVGVLNNL-LYAVGGHDGPLVRKS---VEVYDPTTNAWRQVADMNMCRRNAGVCAVNG 543

Query: 500 CLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISE-MNTG 613
            LYV GG+ +G    L S E YNP  ++W+ +S  M+TG
Sbjct: 544 LLYVVGGD-DG-SCNLASVEYYNPTTDKWTVVSSCMSTG 580



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 33/121 (27%), Positives = 52/121 (42%)
 Frame = +2

Query: 248 SWHAFDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTR 427
           S   +D   + W  +  +P     A   G   ++G    + G    +R  +R V  Y+  
Sbjct: 322 SVECYDFKEERWHQVAELPSRRCRA---GMVYMAGLVFAVGGFNGSLR--VRTVDSYDPV 376

Query: 428 TNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMN 607
            ++W    +M  +R   G+ V+N  LY  GG  +G    L S E YN   N W  ++ MN
Sbjct: 377 KDQWTSVANMRDRRSTLGAAVLNGLLYAVGG-FDG-STGLSSVEAYNIKSNEWFHVAPMN 434

Query: 608 T 610
           T
Sbjct: 435 T 435



 Score = 33.1 bits (74), Expect = 0.66
 Identities = 16/82 (19%), Positives = 44/82 (53%)
 Frame = +2

Query: 359 LYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQ 538
           + + GG+ P   ++R V  Y+ +  +W++  ++  +R   G   +   ++  GG    ++
Sbjct: 309 MVVVGGQAPK--AIRSVECYDFKEERWHQVAELPSRRCRAGMVYMAGLVFAVGGFNGSLR 366

Query: 539 RTLRSAEVYNPNRNRWSCISEM 604
             +R+ + Y+P +++W+ ++ M
Sbjct: 367 --VRTVDSYDPVKDQWTSVANM 386

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>IPP_MOUSE (P28575) Actin-binding protein IPP (MIPP protein) (Murine|
           IAP-promoted placenta-expressed protein)
          Length = 584

 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 38/125 (30%), Positives = 57/125 (45%), Gaps = 4/125 (3%)
 Frame = +2

Query: 248 SWHAFDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTR 427
           S+  +DP+ + W    P+PP  +     G A L+ C +Y  GG +  + ++  V  Y+  
Sbjct: 454 SFEVYDPLSKRWS---PLPPMGTRRAYLGVAALNDC-IYAIGGWNETQDALHTVEKYSFE 509

Query: 428 TNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEG----IQRTLRSAEVYNPNRNRWSCI 595
             KW     M   R    +  +N  LYV+GG           TL S EVYNP+ + W+ I
Sbjct: 510 EEKWVEVASMKVPRAGMCAVTVNGLLYVSGGRSSSHDFLAPGTLDSVEVYNPHSDTWTEI 569

Query: 596 SEMNT 610
             M T
Sbjct: 570 GNMIT 574



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 39/136 (28%), Positives = 58/136 (42%), Gaps = 3/136 (2%)
 Frame = +2

Query: 212 VYVFKRDRDQKL--SWHAFDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDP 385
           VY    ++D  +      +DPV + W ++  +        G G  V  G    L G    
Sbjct: 345 VYAIGGEKDSMIFDCTECYDPVTKQWTTVASMN---HPRCGLGVCVCYGAIYALGGWVGA 401

Query: 386 VRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGG-ECEGIQRTLRSAEV 562
             G+   +  ++   NKW     M   R+ FG C +   +Y  GG   EG++  LRS EV
Sbjct: 402 EIGNT--IERFDPDENKWEVVGSMAVSRYYFGCCEMQGLIYAVGGISNEGLE--LRSFEV 457

Query: 563 YNPNRNRWSCISEMNT 610
           Y+P   RWS +  M T
Sbjct: 458 YDPLSKRWSPLPPMGT 473



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 33/118 (27%), Positives = 49/118 (41%), Gaps = 3/118 (2%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVG---FGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRT 430
           FDP    W  +       S AV    FGC  + G  +Y  GG       +R    Y+  +
Sbjct: 410 FDPDENKWEVVG------SMAVSRYYFGCCEMQGL-IYAVGGISNEGLELRSFEVYDPLS 462

Query: 431 NKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEM 604
            +W   P M  +R   G   +N+C+Y  GG  E  Q  L + E Y+    +W  ++ M
Sbjct: 463 KRWSPLPPMGTRRAYLGVAALNDCIYAIGGWNE-TQDALHTVEKYSFEEEKWVEVASM 519

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>KLH18_HUMAN (O94889) Kelch-like protein 18|
          Length = 509

 Score = 59.7 bits (143), Expect = 7e-09
 Identities = 40/119 (33%), Positives = 60/119 (50%), Gaps = 2/119 (1%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMR--HVVFYNTRTN 433
           FDP+   W    P+    S     G AV++G  LY  GG D   G +R   V  YN  T+
Sbjct: 244 FDPIANCWERCRPMTTARSRV---GVAVVNGL-LYAIGGYD---GQLRLSTVEAYNPETD 296

Query: 434 KWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMNT 610
            W R   M  KR   G+ V++  +YV GG  +G   +L S E Y+P  ++W+ ++ M++
Sbjct: 297 TWTRVGSMNSKRSAMGTVVLDGQIYVCGG-YDG-NSSLSSVETYSPETDKWTVVTSMSS 353



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 29/92 (31%), Positives = 43/92 (46%)
 Frame = +2

Query: 335 CAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVA 514
           C  ++G  +Y  GG +    S+  V  ++   N W R   M   R   G  V+N  LY  
Sbjct: 218 CTSIAGL-IYAVGGLNSAGDSLNVVEVFDPIANCWERCRPMTTARSRVGVAVVNGLLYAI 276

Query: 515 GGECEGIQRTLRSAEVYNPNRNRWSCISEMNT 610
           GG  +G Q  L + E YNP  + W+ +  MN+
Sbjct: 277 GG-YDG-QLRLSTVEAYNPETDTWTRVGSMNS 306



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 36/124 (29%), Positives = 56/124 (45%), Gaps = 3/124 (2%)
 Frame = +2

Query: 248 SWHAFDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVR--GSMRHVVFYN 421
           S   + P    W  +  +    S A   G  V  G  +Y+ GG D ++   S+ H   YN
Sbjct: 334 SVETYSPETDKWTVVTSMSSNRSAA---GVTVFEG-RIYVSGGHDGLQIFSSVEH---YN 386

Query: 422 TRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGG-ECEGIQRTLRSAEVYNPNRNRWSCIS 598
             T  W+ A  ML KR   G+  + + ++V GG +  G    L  AE+Y+   ++W  I 
Sbjct: 387 HHTATWHPAAGMLNKRCRHGAASLGSKMFVCGGYDGSGF---LSIAEMYSSVADQWCLIV 443

Query: 599 EMNT 610
            M+T
Sbjct: 444 PMHT 447



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 33/110 (30%), Positives = 48/110 (43%)
 Frame = +2

Query: 257 AFDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNK 436
           A++P    W  +  +  + S     G  VL G  +Y+ GG D    S+  V  Y+  T+K
Sbjct: 290 AYNPETDTWTRVGSMNSKRS---AMGTVVLDG-QIYVCGGYDG-NSSLSSVETYSPETDK 344

Query: 437 WYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRW 586
           W     M   R   G  V    +YV+GG  +G+Q    S E YN +   W
Sbjct: 345 WTVVTSMSSNRSAAGVTVFEGRIYVSGGH-DGLQ-IFSSVEHYNHHTATW 392

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>IPP_HUMAN (Q9Y573) Actin-binding protein IPP (MIPP protein)|
          Length = 584

 Score = 59.7 bits (143), Expect = 7e-09
 Identities = 41/127 (32%), Positives = 59/127 (46%), Gaps = 6/127 (4%)
 Frame = +2

Query: 248 SWHAFDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTR 427
           S+  +DP+ + W    P+PP  +     G A L+ C +Y  GG +  + ++  V  Y+  
Sbjct: 454 SFEVYDPLSKRW---SPLPPMGTRRAYLGVAALNDC-IYSVGGWNETQDALHTVEKYSFE 509

Query: 428 TNKWYRAPDMLRKRHLFGSCV--INNCLYVAGGECEG----IQRTLRSAEVYNPNRNRWS 589
             KW     M   R   G CV  +N  LYV+GG           TL S EVYNP+ + W+
Sbjct: 510 EEKWVEVASMKVPR--AGMCVVAVNGLLYVSGGRSSSHDFLAPGTLDSVEVYNPHSDTWT 567

Query: 590 CISEMNT 610
            I  M T
Sbjct: 568 EIGNMIT 574



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 41/136 (30%), Positives = 60/136 (44%), Gaps = 3/136 (2%)
 Frame = +2

Query: 212 VYVFKRDRDQKL--SWHAFDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDP 385
           VY    ++D  +      +DPV + W ++  +        G G  V  G    L G    
Sbjct: 345 VYAIGGEKDSMIFDCTECYDPVTKQWTTVASMN---HPRCGLGVCVCYGAIYALGGWVGA 401

Query: 386 VRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGG-ECEGIQRTLRSAEV 562
             G+   +  ++   NKW    +M   R+ FG C +   +YV GG   EGI+  LRS EV
Sbjct: 402 EIGNT--IERFDPDENKWEVVGNMAVSRYYFGCCEMQGLIYVIGGISNEGIE--LRSFEV 457

Query: 563 YNPNRNRWSCISEMNT 610
           Y+P   RWS +  M T
Sbjct: 458 YDPLSKRWSPLPPMGT 473



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 26/92 (28%), Positives = 42/92 (45%)
 Frame = +2

Query: 329 FGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLY 508
           FGC  + G  +Y+ GG       +R    Y+  + +W   P M  +R   G   +N+C+Y
Sbjct: 430 FGCCEMQGL-IYVIGGISNEGIELRSFEVYDPLSKRWSPLPPMGTRRAYLGVAALNDCIY 488

Query: 509 VAGGECEGIQRTLRSAEVYNPNRNRWSCISEM 604
             GG  E  Q  L + E Y+    +W  ++ M
Sbjct: 489 SVGGWNE-TQDALHTVEKYSFEEEKWVEVASM 519

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>KLH20_MOUSE (Q8VCK5) Kelch-like protein 20 (Kelch-like ECT2-interacting|
           protein)
          Length = 604

 Score = 59.3 bits (142), Expect = 9e-09
 Identities = 42/117 (35%), Positives = 54/117 (46%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           +DP    W S   V P  +     G AVL G +LY  GG+D V   +  V  Y+ + NKW
Sbjct: 380 YDPKTNQWSS--DVAPTSTCRTSVGVAVLGG-FLYAVGGQDGV-SCLNIVERYDPKENKW 435

Query: 440 YRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMNT 610
            R   M  +R      V+   LY  GG  +G    L + E YNP  NRW  I+ M T
Sbjct: 436 TRVASMSTRRLGVAVAVLGGFLYAVGGS-DGTS-PLNTVERYNPQENRWHTIAPMGT 490



 Score = 56.6 bits (135), Expect = 6e-08
 Identities = 39/118 (33%), Positives = 58/118 (49%), Gaps = 1/118 (0%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           +DP    W  +  +    +  +G   AVL G +LY  GG D     +  V  YN + N+W
Sbjct: 428 YDPKENKWTRVASMS---TRRLGVAVAVLGG-FLYAVGGSDGT-SPLNTVERYNPQENRW 482

Query: 440 YR-APDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMNT 610
           +  AP   R++HL G  V  + +Y  GG  +  +  L SAE YNP  N+WS +  M +
Sbjct: 483 HTIAPMGTRRKHL-GCAVYQDMIYAVGGRDDTTE--LSSAERYNPRTNQWSPVVAMTS 537



 Score = 49.3 bits (116), Expect = 9e-06
 Identities = 34/116 (29%), Positives = 51/116 (43%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           ++P    W ++ P+          GCAV     +Y  GG+D     +     YN RTN+W
Sbjct: 475 YNPQENRWHTIAPMGTRRKH---LGCAVYQDM-IYAVGGRDDTT-ELSSAERYNPRTNQW 529

Query: 440 YRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMN 607
                M  +R   G  V+N  L   GG  +G    L++ EV++P+ N W     MN
Sbjct: 530 SPVVAMTSRRSGVGLAVVNGQLMAVGG-FDG-TTYLKTIEVFDPDANTWRLYGGMN 583



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 21/58 (36%), Positives = 32/58 (55%)
 Frame = +2

Query: 416 YNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWS 589
           Y+ +TN+W     M ++R   G  V+++ LY  GG  +G    L S E Y+P  N+WS
Sbjct: 333 YDPQTNEWRMVASMSKRRCGVGVSVLDDLLYAVGGH-DG-SSYLNSVERYDPKTNQWS 388

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>KLH20_HUMAN (Q9Y2M5) Kelch-like protein 20 (Kelch-like ECT2-interacting|
           protein) (Kelch-like protein X)
          Length = 604

 Score = 59.3 bits (142), Expect = 9e-09
 Identities = 42/117 (35%), Positives = 54/117 (46%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           +DP    W S   V P  +     G AVL G +LY  GG+D V   +  V  Y+ + NKW
Sbjct: 380 YDPKTNQWSS--DVAPTSTCRTSVGVAVLGG-FLYAVGGQDGV-SCLNIVERYDPKENKW 435

Query: 440 YRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMNT 610
            R   M  +R      V+   LY  GG  +G    L + E YNP  NRW  I+ M T
Sbjct: 436 TRVASMSTRRLGVAVAVLGGFLYAVGGS-DGTS-PLNTVERYNPQENRWHTIAPMGT 490



 Score = 56.6 bits (135), Expect = 6e-08
 Identities = 39/118 (33%), Positives = 58/118 (49%), Gaps = 1/118 (0%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           +DP    W  +  +    +  +G   AVL G +LY  GG D     +  V  YN + N+W
Sbjct: 428 YDPKENKWTRVASMS---TRRLGVAVAVLGG-FLYAVGGSDGT-SPLNTVERYNPQENRW 482

Query: 440 YR-APDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMNT 610
           +  AP   R++HL G  V  + +Y  GG  +  +  L SAE YNP  N+WS +  M +
Sbjct: 483 HTIAPMGTRRKHL-GCAVYQDMIYAVGGRDDTTE--LSSAERYNPRTNQWSPVVAMTS 537



 Score = 49.3 bits (116), Expect = 9e-06
 Identities = 34/116 (29%), Positives = 51/116 (43%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           ++P    W ++ P+          GCAV     +Y  GG+D     +     YN RTN+W
Sbjct: 475 YNPQENRWHTIAPMGTRRKH---LGCAVYQDM-IYAVGGRDDTT-ELSSAERYNPRTNQW 529

Query: 440 YRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMN 607
                M  +R   G  V+N  L   GG  +G    L++ EV++P+ N W     MN
Sbjct: 530 SPVVAMTSRRSGVGLAVVNGQLMAVGG-FDG-TTYLKTIEVFDPDANTWRLYGGMN 583



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 21/58 (36%), Positives = 32/58 (55%)
 Frame = +2

Query: 416 YNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWS 589
           Y+ +TN+W     M ++R   G  V+++ LY  GG  +G    L S E Y+P  N+WS
Sbjct: 333 YDPQTNEWRMVASMSKRRCGVGVSVLDDLLYAVGGH-DG-SSYLNSVERYDPKTNQWS 388

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>ENC1_MOUSE (O35709) Ectoderm-neural cortex 1 protein (ENC-1)|
          Length = 589

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 31/100 (31%), Positives = 49/100 (49%), Gaps = 7/100 (7%)
 Frame = +2

Query: 335 CAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVA 514
           CA+  GC +Y+ GG+    G  + V  Y+T   +W +A  ML  R   GS  + +CLYV 
Sbjct: 336 CAI--GCKVYITGGRGSENGVSKDVWVYDTLHEEWSKAAPMLVARFGHGSAELKHCLYVV 393

Query: 515 GGECEGI-------QRTLRSAEVYNPNRNRWSCISEMNTG 613
           GG              +L+  E Y+P  N+W+ ++ +  G
Sbjct: 394 GGHTAATGCLPASPSVSLKQVEQYDPTTNKWTMVAPLREG 433



 Score = 37.4 bits (85), Expect = 0.035
 Identities = 26/100 (26%), Positives = 46/100 (46%)
 Frame = +2

Query: 299 VPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLF 478
           VP    +   +  A + G  +++ GG         +   +N+ T +W +  D+  KR   
Sbjct: 474 VPATCPQPWRYTAAAVLGNQIFIMGGDTEFSACSAYK--FNSETYQWTKVGDVTAKRMSC 531

Query: 479 GSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCIS 598
            +    N LYV GG   GIQR  ++ + Y+P  + W+ I+
Sbjct: 532 HAVASGNKLYVVGGYF-GIQR-CKTLDCYDPTLDVWNSIT 569



 Score = 34.7 bits (78), Expect = 0.23
 Identities = 24/115 (20%), Positives = 46/115 (40%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           +DP    W  + P+     E V     V +   L+ FGG       +  V  Y+   N+W
Sbjct: 417 YDPTTNKWTMVAPL----REGVSNAAVVSAKLKLFAFGGTSVSHDKLPKVQCYDQCENRW 472

Query: 440 YRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEM 604
                  +      + V+ N +++ GG+ E    +  SA  +N    +W+ + ++
Sbjct: 473 SVPATCPQPWRYTAAAVLGNQIFIMGGDTE---FSACSAYKFNSETYQWTKVGDV 524

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>ENC1_HUMAN (O14682) Ectoderm-neural cortex 1 protein (ENC-1) (p53-induced|
           protein 10) (Nuclear matrix protein NRP/B)
          Length = 589

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 31/100 (31%), Positives = 49/100 (49%), Gaps = 7/100 (7%)
 Frame = +2

Query: 335 CAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVA 514
           CA+  GC +Y+ GG+    G  + V  Y+T   +W +A  ML  R   GS  + +CLYV 
Sbjct: 336 CAI--GCKVYITGGRGSENGVSKDVWVYDTLHEEWSKAAPMLVARFGHGSAELKHCLYVV 393

Query: 515 GGECEGI-------QRTLRSAEVYNPNRNRWSCISEMNTG 613
           GG              +L+  E Y+P  N+W+ ++ +  G
Sbjct: 394 GGHTAATGCLPASPSVSLKQVEHYDPTINKWTMVAPLREG 433



 Score = 37.4 bits (85), Expect = 0.035
 Identities = 26/100 (26%), Positives = 46/100 (46%)
 Frame = +2

Query: 299 VPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLF 478
           VP    +   +  A + G  +++ GG         +   +N+ T +W +  D+  KR   
Sbjct: 474 VPATCPQPWRYTAAAVLGNQIFIMGGDTEFSACSAYK--FNSETYQWTKVGDVTAKRMSC 531

Query: 479 GSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCIS 598
            +    N LYV GG   GIQR  ++ + Y+P  + W+ I+
Sbjct: 532 HAVASGNKLYVVGGYF-GIQR-CKTLDCYDPTLDVWNSIT 569



 Score = 34.3 bits (77), Expect = 0.29
 Identities = 24/115 (20%), Positives = 46/115 (40%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           +DP    W  + P+     E V     V +   L+ FGG       +  V  Y+   N+W
Sbjct: 417 YDPTINKWTMVAPL----REGVSNAAVVSAKLKLFAFGGTSVSHDKLPKVQCYDQCENRW 472

Query: 440 YRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEM 604
                  +      + V+ N +++ GG+ E    +  SA  +N    +W+ + ++
Sbjct: 473 TVPATCPQPWRYTAAAVLGNQIFIMGGDTE---FSACSAYKFNSETYQWTKVGDV 524

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>KLHL3_HUMAN (Q9UH77) Kelch-like protein 3|
          Length = 587

 Score = 55.8 bits (133), Expect = 9e-08
 Identities = 37/117 (31%), Positives = 55/117 (47%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           +D V   W S+  +    S     G AVL+   LY  GG D   G +  V  Y+ +TN+W
Sbjct: 367 YDGVKDQWTSIASMQERRST---LGAAVLNDL-LYAVGGFDGSTG-LASVEAYSYKTNEW 421

Query: 440 YRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMNT 610
           +    M  +R   G  V+   LY  GG     ++ L + E YNP  N W  +++M+T
Sbjct: 422 FFVAPMNTRRSSVGVGVVEGKLYAVGGYDGASRQCLSTVEQYNPATNEWIYVADMST 478



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 41/99 (41%), Positives = 52/99 (52%), Gaps = 3/99 (3%)
 Frame = +2

Query: 326 GFGCAVLSGCYLYLFGGKDP--VRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINN 499
           G G  VLSG  LY  GG D   VR S   V  Y+  TN W +  DM   R   G C +N 
Sbjct: 482 GAGVGVLSG-QLYATGGHDGPLVRKS---VEVYDPGTNTWKQVADMNMCRRNAGVCAVNG 537

Query: 500 CLYVAGGECEGIQRTLRSAEVYNPNRNRWSCI-SEMNTG 613
            LYV GG+ +G    L S E YNP  ++W+ + + M+TG
Sbjct: 538 LLYVVGGD-DG-SCNLASVEYYNPVTDKWTLLPTNMSTG 574



 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 36/104 (34%), Positives = 49/104 (47%), Gaps = 1/104 (0%)
 Frame = +2

Query: 299 VPPEYSEAVGFGCAVLSGCYLYLFGGKDPV-RGSMRHVVFYNTRTNKWYRAPDMLRKRHL 475
           V P  +     G  V+ G  LY  GG D   R  +  V  YN  TN+W    DM  +R  
Sbjct: 424 VAPMNTRRSSVGVGVVEG-KLYAVGGYDGASRQCLSTVEQYNPATNEWIYVADMSTRRSG 482

Query: 476 FGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMN 607
            G  V++  LY  GG    + R  +S EVY+P  N W  +++MN
Sbjct: 483 AGVGVLSGQLYATGGHDGPLVR--KSVEVYDPGTNTWKQVADMN 524



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 35/123 (28%), Positives = 54/123 (43%), Gaps = 2/123 (1%)
 Frame = +2

Query: 248 SWHAFDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMR--HVVFYN 421
           S   +D     W  +  +P     A   G   ++G ++Y  GG     GS+R   V  Y+
Sbjct: 316 SVECYDFEEDRWDQIAELPSRRCRA---GVVFMAG-HVYAVGG---FNGSLRVRTVDVYD 368

Query: 422 TRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISE 601
              ++W     M  +R   G+ V+N+ LY  GG  +G    L S E Y+   N W  ++ 
Sbjct: 369 GVKDQWTSIASMQERRSTLGAAVLNDLLYAVGG-FDG-STGLASVEAYSYKTNEWFFVAP 426

Query: 602 MNT 610
           MNT
Sbjct: 427 MNT 429

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>KELC_ANOST (Q70JS2) Ring canal kelch homolog (Kelch-like protein 1) [Contains:|
           Kelch short protein]
          Length = 1499

 Score = 55.8 bits (133), Expect = 9e-08
 Identities = 38/116 (32%), Positives = 54/116 (46%), Gaps = 1/116 (0%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPV-RGSMRHVVFYNTRTNK 436
           FDP  Q WR +  +    S     G  V++G  LY  GG D   R  +  V  YN  T+ 
Sbjct: 463 FDPKRQEWRLIASMSTRRSSV---GVGVVNGL-LYAVGGYDGASRQCLASVERYNPSTDT 518

Query: 437 WYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEM 604
           W +  +M  +R   G  V++N LY  GG    + R  +S E Y+P  N W  + +M
Sbjct: 519 WTQIAEMSARRSGAGVGVLDNILYAVGGHDGPLVR--KSVEAYDPATNTWRAVGDM 572



 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 35/116 (30%), Positives = 54/116 (46%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           +DPV   W +   +    S     G AVL+ C +Y  GG D   G +     ++ +  +W
Sbjct: 416 YDPVLDQWTTSHNMEARRST---LGVAVLNNC-IYAVGGFDGSTG-LSSAEMFDPKRQEW 470

Query: 440 YRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMN 607
                M  +R   G  V+N  LY  GG     ++ L S E YNP+ + W+ I+EM+
Sbjct: 471 RLIASMSTRRSSVGVGVVNGLLYAVGGYDGASRQCLASVERYNPSTDTWTQIAEMS 526



 Score = 52.8 bits (125), Expect = 8e-07
 Identities = 40/123 (32%), Positives = 60/123 (48%), Gaps = 2/123 (1%)
 Frame = +2

Query: 248 SWHAFDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMR--HVVFYN 421
           S   +D   + W  +  +P     A   G AVL G  +Y  GG     GS+R   V  Y+
Sbjct: 365 SVECYDLREEKWYQVAEMPTRRCRA---GLAVL-GDKVYAVGG---FNGSLRVKTVDVYD 417

Query: 422 TRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISE 601
              ++W  + +M  +R   G  V+NNC+Y  GG  +G    L SAE+++P R  W  I+ 
Sbjct: 418 PVLDQWTTSHNMEARRSTLGVAVLNNCIYAVGG-FDG-STGLSSAEMFDPKRQEWRLIAS 475

Query: 602 MNT 610
           M+T
Sbjct: 476 MST 478



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 41/121 (33%), Positives = 53/121 (43%), Gaps = 3/121 (2%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDP--VRGSMRHVVFYNTRTN 433
           ++P    W  +  +    S   G G  VL    LY  GG D   VR S   V  Y+  TN
Sbjct: 512 YNPSTDTWTQIAEMSARRS---GAGVGVLDNI-LYAVGGHDGPLVRKS---VEAYDPATN 564

Query: 434 KWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCI-SEMNT 610
            W    DM   R   G    N  LYV GG+ +G+   L S EVY+P  + W  + S M+ 
Sbjct: 565 TWRAVGDMAFCRRNAGVVAHNGMLYVVGGD-DGLS-NLASVEVYSPESDSWRILPSSMSI 622

Query: 611 G 613
           G
Sbjct: 623 G 623



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 23/82 (28%), Positives = 44/82 (53%)
 Frame = +2

Query: 359 LYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQ 538
           L + GG+ P   ++R V  Y+ R  KWY+  +M  +R   G  V+ + +Y  GG    ++
Sbjct: 352 LLVIGGQAPK--AIRSVECYDLREEKWYQVAEMPTRRCRAGLAVLGDKVYAVGGFNGSLR 409

Query: 539 RTLRSAEVYNPNRNRWSCISEM 604
             +++ +VY+P  ++W+    M
Sbjct: 410 --VKTVDVYDPVLDQWTTSHNM 429

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>KLDC5_HUMAN (Q9P2K6) Kelch domain-containing protein 5|
          Length = 505

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 29/102 (28%), Positives = 50/102 (49%)
 Frame = +2

Query: 299 VPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLF 478
           +PP+     G+G A+L   YL++ GG       +     YN  TN+W +   M +KR  F
Sbjct: 236 LPPDLVNVRGYGSAILDN-YLFIVGGYRITSQEISAAHSYNPSTNEWLQVASMNQKRSNF 294

Query: 479 GSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEM 604
               +N+ LY  GG+       + + E YNP ++ W+ ++ +
Sbjct: 295 KLVAVNSKLYAIGGQ------AVSNVECYNPEQDAWNFVAPL 330



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 36/127 (28%), Positives = 56/127 (44%), Gaps = 13/127 (10%)
 Frame = +2

Query: 266 PVHQLWRSLPPVPPEYS------EAVGFGCAVLSGCYLYLFG--GKDPVRGSMRHVVFYN 421
           P   L  S P  P + S      EA   G  VL     +L G     P +G    ++ Y 
Sbjct: 164 PQFHLLGSPPQAPGDVSLKQRLREARMTGTPVLVALGDFLGGPLAPHPYQGEPPSMLRYE 223

Query: 422 TRTNKWYRA-----PDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRW 586
             T +W+       PD++  R  +GS +++N L++ GG     Q  + +A  YNP+ N W
Sbjct: 224 EMTERWFPLANNLPPDLVNVRG-YGSAILDNYLFIVGGYRITSQE-ISAAHSYNPSTNEW 281

Query: 587 SCISEMN 607
             ++ MN
Sbjct: 282 LQVASMN 288

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>KLHL5_HUMAN (Q96PQ7) Kelch-like protein 5|
          Length = 755

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 31/84 (36%), Positives = 47/84 (55%)
 Frame = +2

Query: 359 LYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQ 538
           L+  GG D  +G+   +  Y+ RTN W    +M  +R  FG  V+++ LYV GG  +G+ 
Sbjct: 469 LFAVGGMDSTKGATS-IEKYDLRTNMWTPVANMNGRRLQFGVAVLDDKLYVVGGR-DGL- 525

Query: 539 RTLRSAEVYNPNRNRWSCISEMNT 610
           +TL + E YNP    WS +  M+T
Sbjct: 526 KTLNTVECYNPKTKTWSVMPPMST 549



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 33/105 (31%), Positives = 52/105 (49%)
 Frame = +2

Query: 296 PVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHL 475
           PV       + FG AVL    LY+ GG+D ++ ++  V  YN +T  W   P M   RH 
Sbjct: 496 PVANMNGRRLQFGVAVLDD-KLYVVGGRDGLK-TLNTVECYNPKTKTWSVMPPMSTHRHG 553

Query: 476 FGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMNT 610
            G  V+   +Y  GG  +G    L + E ++P   +W+ ++ M+T
Sbjct: 554 LGVAVLEGPMYAVGGH-DG-WSYLNTVERWDPQARQWNFVATMST 596



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 34/120 (28%), Positives = 51/120 (42%), Gaps = 4/120 (3%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           +DP  + W  +  +    S     G AVLSG  LY  GG+D     ++ V  ++  TNKW
Sbjct: 581 WDPQARQWNFVATMSTPRSTV---GVAVLSG-KLYAVGGRDG-SSCLKSVECFDPHTNKW 635

Query: 440 YRAPDMLRKRHLFGSCVINNCLYVAGGE----CEGIQRTLRSAEVYNPNRNRWSCISEMN 607
                M ++R   G    N  LY  GG          R     E Y+P  + W+ ++ M+
Sbjct: 636 TLCAQMSKRRGGVGVTTWNGLLYAIGGHDAPASNLTSRLSDCVERYDPKTDMWTAVASMS 695



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 34/127 (26%), Positives = 51/127 (40%), Gaps = 5/127 (3%)
 Frame = +2

Query: 248 SWHAFDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRH-----VV 412
           S   FDP    W     +        G G    +G  LY  GG D    ++       V 
Sbjct: 624 SVECFDPHTNKWTLCAQMSKRRG---GVGVTTWNGL-LYAIGGHDAPASNLTSRLSDCVE 679

Query: 413 FYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSC 592
            Y+ +T+ W     M   R   G C++ + LY  GG  +G Q  L + E Y+P  N W+ 
Sbjct: 680 RYDPKTDMWTAVASMSISRDAVGVCLLGDKLYAVGG-YDG-QAYLNTVEAYDPQTNEWTQ 737

Query: 593 ISEMNTG 613
           ++ +  G
Sbjct: 738 VAPLCLG 744

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>KEAP1_HUMAN (Q14145) Kelch-like ECH-associated protein 1 (Cytosolic inhibitor|
           of Nrf2) (Kelch-like protein 19)
          Length = 624

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 39/119 (32%), Positives = 55/119 (46%), Gaps = 2/119 (1%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRH--VVFYNTRTN 433
           ++P+   W    P+    +     G  V+ G ++Y  GG     G + H  V  Y    +
Sbjct: 396 YNPMTNQWSPCAPMSVPRNR---IGVGVIDG-HIYAVGGS---HGCIHHNSVERYEPERD 448

Query: 434 KWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMNT 610
           +W+    ML +R   G  V+N  LY  GG  +G  R L SAE Y P RN W  I+ MNT
Sbjct: 449 EWHLVAPMLTRRIGVGVAVLNRLLYAVGG-FDGTNR-LNSAECYYPERNEWRMITAMNT 505



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 36/115 (31%), Positives = 53/115 (46%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           ++P    W  + P+    +  +G G AVL+   LY  GG D          +Y  R N+W
Sbjct: 443 YEPERDEWHLVAPM---LTRRIGVGVAVLNRL-LYAVGGFDGTNRLNSAECYYPER-NEW 497

Query: 440 YRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEM 604
                M   R   G CV++NC+Y AGG  +G Q  L S E Y+     W+ ++ M
Sbjct: 498 RMITAMNTIRSGAGVCVLHNCIYAAGG-YDG-QDQLNSVERYDVETETWTFVAPM 550



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 36/122 (29%), Positives = 52/122 (42%)
 Frame = +2

Query: 248 SWHAFDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTR 427
           S   + P    WR +  +    S   G G  VL  C +Y  GG D  +  +  V  Y+  
Sbjct: 486 SAECYYPERNEWRMITAMNTIRS---GAGVCVLHNC-IYAAGGYDG-QDQLNSVERYDVE 540

Query: 428 TNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMN 607
           T  W     M  +R   G  V    +YV GG  +G    L S E Y+P+ + WS ++ M 
Sbjct: 541 TETWTFVAPMKHRRSALGITVHQGRIYVLGGY-DG-HTFLDSVECYDPDTDTWSEVTRMT 598

Query: 608 TG 613
           +G
Sbjct: 599 SG 600



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 26/88 (29%), Positives = 37/88 (42%), Gaps = 2/88 (2%)
 Frame = +2

Query: 350 GCYLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECE 529
           G  +Y  GG    R S+ ++  YN     W R  D+   R     CV+   LY  GG   
Sbjct: 325 GRLIYTAGGY--FRQSLSYLEAYNPSNGTWLRLADLQVPRSGLAGCVVGGLLYAVGGRNN 382

Query: 530 GIQRTLRSA--EVYNPNRNRWSCISEMN 607
                  S+  + YNP  N+WS  + M+
Sbjct: 383 SPDGNTDSSALDCYNPMTNQWSPCAPMS 410

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>KLDC5_MOUSE (Q8BFQ9) Kelch domain-containing protein 5|
          Length = 493

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 29/102 (28%), Positives = 50/102 (49%)
 Frame = +2

Query: 299 VPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLF 478
           +PP+     G+G A+L   YL++ GG       +     YN  TN+W +   M +KR  F
Sbjct: 224 LPPDLVNVRGYGSAILDN-YLFIVGGYRITSQEISAAHSYNPITNEWLQVASMNQKRSNF 282

Query: 479 GSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEM 604
               +N+ LY  GG+       + + E YNP ++ W+ ++ +
Sbjct: 283 KLVAVNSKLYAIGGQ------AVSNVECYNPEQDAWNFVAPL 318



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 23/80 (28%), Positives = 40/80 (50%), Gaps = 5/80 (6%)
 Frame = +2

Query: 383 PVRGSMRHVVFYNTRTNKWYRA-----PDMLRKRHLFGSCVINNCLYVAGGECEGIQRTL 547
           P +G    ++ Y   T +W+       PD++  R  +GS +++N L++ GG     Q  +
Sbjct: 199 PYQGEPPSMLRYEETTERWFPLANNLPPDLVNVRG-YGSAILDNYLFIVGGYRITSQE-I 256

Query: 548 RSAEVYNPNRNRWSCISEMN 607
            +A  YNP  N W  ++ MN
Sbjct: 257 SAAHSYNPITNEWLQVASMN 276

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>KLHL4_HUMAN (Q9C0H6) Kelch-like protein 4|
          Length = 718

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 32/84 (38%), Positives = 47/84 (55%)
 Frame = +2

Query: 359 LYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQ 538
           LY  GG D ++G+   +  Y+ RTN W     M  +R  FG  VI+N LYV GG  +G+ 
Sbjct: 431 LYAVGGMDAMKGTTT-IEKYDLRTNSWLHIGTMNGRRLQFGVAVIDNKLYVVGGR-DGL- 487

Query: 539 RTLRSAEVYNPNRNRWSCISEMNT 610
           +TL + E +NP    W+ +  M+T
Sbjct: 488 KTLNTVECFNPVGKIWTVMPPMST 511



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 35/116 (30%), Positives = 55/116 (47%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           F+PV ++W  +PP+    +   G G A L G  +Y  GG D     +  V  ++    +W
Sbjct: 496 FNPVGKIWTVMPPMS---THRHGLGVATLEGP-MYAVGGHDGW-SYLNTVERWDPEGRQW 550

Query: 440 YRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMN 607
                M   R   G   +NN LY  GG  +G    L+S E ++P+ N+WS  + M+
Sbjct: 551 NYVASMSTPRSTVGVVALNNKLYAIGGR-DG-SSCLKSMEYFDPHTNKWSLCAPMS 604



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 4/87 (4%)
 Frame = +2

Query: 359 LYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGE----C 526
           LY  GG+D     ++ + +++  TNKW     M ++R   G    N  LYV GG      
Sbjct: 572 LYAIGGRDG-SSCLKSMEYFDPHTNKWSLCAPMSKRRGGVGVATYNGFLYVVGGHDAPAS 630

Query: 527 EGIQRTLRSAEVYNPNRNRWSCISEMN 607
               R     E Y+P  + WS ++ ++
Sbjct: 631 NHCSRLSDCVERYDPKGDSWSTVAPLS 657



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 27/94 (28%), Positives = 46/94 (48%)
 Frame = +2

Query: 329 FGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLY 508
           FG AV+    LY+ GG+D ++ ++  V  +N     W   P M   RH  G   +   +Y
Sbjct: 469 FGVAVIDN-KLYVVGGRDGLK-TLNTVECFNPVGKIWTVMPPMSTHRHGLGVATLEGPMY 526

Query: 509 VAGGECEGIQRTLRSAEVYNPNRNRWSCISEMNT 610
             GG  +G    L + E ++P   +W+ ++ M+T
Sbjct: 527 AVGGH-DG-WSYLNTVERWDPEGRQWNYVASMST 558



 Score = 37.4 bits (85), Expect = 0.035
 Identities = 35/127 (27%), Positives = 49/127 (38%), Gaps = 5/127 (3%)
 Frame = +2

Query: 248 SWHAFDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKD-PVRGSMRH----VV 412
           S   FDP    W    P+        G G A  +G +LY+ GG D P           V 
Sbjct: 586 SMEYFDPHTNKWSLCAPMSKRRG---GVGVATYNG-FLYVVGGHDAPASNHCSRLSDCVE 641

Query: 413 FYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSC 592
            Y+ + + W     +   R     C + + LYV GG  +G    L + E Y+  RN W  
Sbjct: 642 RYDPKGDSWSTVAPLSVPRDAVAVCPLGDKLYVVGG-YDG-HTYLNTVESYDAQRNEWKE 699

Query: 593 ISEMNTG 613
              +N G
Sbjct: 700 EVPVNIG 706

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>KELC_DROME (Q04652) Ring canal kelch protein [Contains: Kelch short protein]|
          Length = 1477

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 35/117 (29%), Positives = 55/117 (47%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           +DP    W +   +    S     G AVL+GC +Y  GG D   G +     Y+ +T+ W
Sbjct: 469 YDPATDQWANCSNMEARRST---LGVAVLNGC-IYAVGGFDGTTG-LSSAEMYDPKTDIW 523

Query: 440 YRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMNT 610
                M  +R   G  V++  LY  GG     ++ L S E YNP+ + W  ++EM++
Sbjct: 524 RFIASMSTRRSSVGVGVVHGLLYAVGGYDGFTRQCLSSVERYNPDTDTWVNVAEMSS 580



 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 37/117 (31%), Positives = 53/117 (45%), Gaps = 1/117 (0%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDP-VRGSMRHVVFYNTRTNK 436
           +DP   +WR +  +    S     G  V+ G  LY  GG D   R  +  V  YN  T+ 
Sbjct: 516 YDPKTDIWRFIASMSTRRSSV---GVGVVHGL-LYAVGGYDGFTRQCLSSVERYNPDTDT 571

Query: 437 WYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMN 607
           W    +M  +R   G  V+NN LY  GG    + R  RS E Y+   N W  +++M+
Sbjct: 572 WVNVAEMSSRRSGAGVGVLNNILYAVGGHDGPMVR--RSVEAYDCETNSWRSVADMS 626



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 34/95 (35%), Positives = 50/95 (52%), Gaps = 2/95 (2%)
 Frame = +2

Query: 332 GCAVLSGCYLYLFGGKDPVRGSMR--HVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCL 505
           G +VL G  +Y  GG     GS+R   V  Y+  T++W    +M  +R   G  V+N C+
Sbjct: 443 GLSVL-GDKVYAVGG---FNGSLRVRTVDVYDPATDQWANCSNMEARRSTLGVAVLNGCI 498

Query: 506 YVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMNT 610
           Y  GG  +G    L SAE+Y+P  + W  I+ M+T
Sbjct: 499 YAVGG-FDG-TTGLSSAEMYDPKTDIWRFIASMST 531



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 26/82 (31%), Positives = 47/82 (57%)
 Frame = +2

Query: 359 LYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQ 538
           L + GG+ P   ++R V +Y+ R  KWY+A +M  +R   G  V+ + +Y  GG    ++
Sbjct: 405 LLVIGGQAPK--AIRSVEWYDLREEKWYQAAEMPNRRCRSGLSVLGDKVYAVGGFNGSLR 462

Query: 539 RTLRSAEVYNPNRNRWSCISEM 604
             +R+ +VY+P  ++W+  S M
Sbjct: 463 --VRTVDVYDPATDQWANCSNM 482



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 36/101 (35%), Positives = 45/101 (44%), Gaps = 2/101 (1%)
 Frame = +2

Query: 314 SEAVGFGCAVLSGCYLYLFGGKDPVRGSM--RHVVFYNTRTNKWYRAPDMLRKRHLFGSC 487
           S   G G  VL+   LY  GG D   G M  R V  Y+  TN W    DM   R   G  
Sbjct: 580 SRRSGAGVGVLNNI-LYAVGGHD---GPMVRRSVEAYDCETNSWRSVADMSYCRRNAGVV 635

Query: 488 VINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMNT 610
             +  LYV GG+ +G    L S EVY P+ + W  +  + T
Sbjct: 636 AHDGLLYVVGGD-DGTS-NLASVEVYCPDSDSWRILPALMT 674

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>GAN_HUMAN (Q9H2C0) Gigaxonin (Kelch-like protein 16)|
          Length = 597

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 35/110 (31%), Positives = 53/110 (48%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           +DP  QLW  L P+       +  G     G +L++FGG+D  + ++     Y+   N W
Sbjct: 299 YDPNRQLWIELAPLS---MPRINHGVLSAEG-FLFVFGGQDENKQTLSSGEKYDPDANTW 354

Query: 440 YRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWS 589
              P M   RH FG   I+  LY+ GGE +G ++ L S E Y+     W+
Sbjct: 355 TALPPMNEARHNFGIVEIDGMLYILGGE-DG-EKELISMECYDIYSKTWT 402



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 33/151 (21%), Positives = 59/151 (39%), Gaps = 9/151 (5%)
 Frame = +2

Query: 182 RKKFGMAE--EWVYVFKRDRDQK--LSWHAFDPVHQLWRSLPPVPPEYSEAVGFGCAVLS 349
           R  FG+ E    +Y+   +  +K  +S   +D   + W       P+ +     GC    
Sbjct: 364 RHNFGIVEIDGMLYILGGEDGEKELISMECYDIYSKTWTK----QPDLTMVRKIGCYAAM 419

Query: 350 GCYLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGG--- 520
              +Y  GG    +     V  Y+ RT +W     +  +R    +C +   LYV GG   
Sbjct: 420 KKKIYAMGGGSYGK-LFESVECYDPRTQQWTAICPLKERRFGAVACGVAMELYVFGGVRS 478

Query: 521 --ECEGIQRTLRSAEVYNPNRNRWSCISEMN 607
             + +G +     +E Y+    RW  +++ N
Sbjct: 479 REDAQGSEMVTCKSEFYHDEFKRWIYLNDQN 509



 Score = 35.0 bits (79), Expect = 0.17
 Identities = 32/131 (24%), Positives = 51/131 (38%), Gaps = 6/131 (4%)
 Frame = +2

Query: 233 RDQKLSWHAFDPVHQLWRSLPPVPPEYSEAV--GFGCAVLSGCYLYLFG----GKDPVRG 394
           R+Q L+      + +   ++P   P+  EA+   F     S C + + G     + P   
Sbjct: 232 REQMLNEPLVREIVKECSNIPLSQPQQGEAMLANFKPRGYSECIVTVGGEERVSRKPTAA 291

Query: 395 SMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPN 574
                  Y+     W     +   R   G       L+V GG+ E  Q TL S E Y+P+
Sbjct: 292 MRCMCPLYDPNRQLWIELAPLSMPRINHGVLSAEGFLFVFGGQDENKQ-TLSSGEKYDPD 350

Query: 575 RNRWSCISEMN 607
            N W+ +  MN
Sbjct: 351 ANTWTALPPMN 361

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>KLHL1_HUMAN (Q9NR64) Kelch-like protein 1|
          Length = 748

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 32/84 (38%), Positives = 48/84 (57%)
 Frame = +2

Query: 359 LYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQ 538
           LY  GG D  +G+   +  Y+ RTN W +A  M  +R  FG  VI++ L+V GG  +G+ 
Sbjct: 461 LYAVGGMDNNKGATT-IEKYDLRTNLWIQAGMMNGRRLQFGVAVIDDKLFVIGGR-DGL- 517

Query: 539 RTLRSAEVYNPNRNRWSCISEMNT 610
           +TL + E YNP    W+ +  M+T
Sbjct: 518 KTLNTVECYNPKTKTWTVLPPMST 541



 Score = 49.3 bits (116), Expect = 9e-06
 Identities = 35/127 (27%), Positives = 55/127 (43%), Gaps = 5/127 (3%)
 Frame = +2

Query: 248 SWHAFDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGS-----MRHVV 412
           S   +DP    W    P+        G G A   G +LY  GG D    +     + +V 
Sbjct: 616 SMEYYDPHTNKWNMCAPMCKRRG---GVGVATCDG-FLYAVGGHDAPASNHCSRLLDYVE 671

Query: 413 FYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSC 592
            Y+ +T+ W     +   R   G C++ + LY  GG  +G Q  L + E Y+P  N W+ 
Sbjct: 672 RYDPKTDTWTMVAPLSMPRDAVGVCLLGDRLYAVGG-YDG-QTYLNTMESYDPQTNEWTQ 729

Query: 593 ISEMNTG 613
           ++ +N G
Sbjct: 730 MASLNIG 736



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 28/93 (30%), Positives = 48/93 (51%)
 Frame = +2

Query: 329 FGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLY 508
           FG AV+    L++ GG+D ++ ++  V  YN +T  W   P M   RH  G  V+   +Y
Sbjct: 499 FGVAVIDD-KLFVIGGRDGLK-TLNTVECYNPKTKTWTVLPPMSTHRHGLGVTVLEGPIY 556

Query: 509 VAGGECEGIQRTLRSAEVYNPNRNRWSCISEMN 607
             GG  +G    L + E ++P   +W+ ++ M+
Sbjct: 557 AVGGH-DG-WSYLNTVERWDPQSQQWTFVASMS 587



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 32/120 (26%), Positives = 51/120 (42%), Gaps = 4/120 (3%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           +DP  Q W  +  +    S     G A L+G  LY  GG+D     +  + +Y+  TNKW
Sbjct: 573 WDPQSQQWTFVASMSIARSTV---GVAALNG-KLYSVGGRDG-SSCLSSMEYYDPHTNKW 627

Query: 440 YRAPDMLRKRHLFGSCVINNCLYVAGGE----CEGIQRTLRSAEVYNPNRNRWSCISEMN 607
                M ++R   G    +  LY  GG          R L   E Y+P  + W+ ++ ++
Sbjct: 628 NMCAPMCKRRGGVGVATCDGFLYAVGGHDAPASNHCSRLLDYVERYDPKTDTWTMVAPLS 687

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>KLHL1_MOUSE (Q9JI74) Kelch-like protein 1|
          Length = 751

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 32/84 (38%), Positives = 48/84 (57%)
 Frame = +2

Query: 359 LYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQ 538
           LY  GG D  +G+   +  Y+ RTN W +A  M  +R  FG  VI++ L+V GG  +G+ 
Sbjct: 464 LYAVGGMDNNKGATT-IEKYDLRTNLWIQAGMMNGRRLQFGVAVIDDKLFVIGGR-DGL- 520

Query: 539 RTLRSAEVYNPNRNRWSCISEMNT 610
           +TL + E YNP    W+ +  M+T
Sbjct: 521 KTLNTVECYNPKTKTWTVLPPMST 544



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 36/127 (28%), Positives = 56/127 (44%), Gaps = 5/127 (3%)
 Frame = +2

Query: 248 SWHAFDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGS-----MRHVV 412
           S   +DP    W   PP+  +     G G A   G +LY  GG D    +     + +V 
Sbjct: 619 SMEYYDPHTNKWSMCPPMCKKRG---GVGVATCDG-FLYAVGGHDAPASNHCSRLLDYVE 674

Query: 413 FYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSC 592
            Y  +T+ W     +   R   G C++ + LY  GG  +G Q  L + E Y+P  N W+ 
Sbjct: 675 RYEPKTDTWTMVAPLSMPRDAVGVCLLGDRLYAVGG-YDG-QTYLNTMESYDPQTNEWTQ 732

Query: 593 ISEMNTG 613
           ++ +N G
Sbjct: 733 MASLNIG 739



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 34/120 (28%), Positives = 51/120 (42%), Gaps = 4/120 (3%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           +DP  Q W  +  +    S     G A L+G  LY  GG+D     +  + +Y+  TNKW
Sbjct: 576 WDPQSQQWTYVASMSIARSTV---GVAALNG-KLYSVGGRDG-SSCLSSMEYYDPHTNKW 630

Query: 440 YRAPDMLRKRHLFGSCVINNCLYVAGGE----CEGIQRTLRSAEVYNPNRNRWSCISEMN 607
              P M +KR   G    +  LY  GG          R L   E Y P  + W+ ++ ++
Sbjct: 631 SMCPPMCKKRGGVGVATCDGFLYAVGGHDAPASNHCSRLLDYVERYEPKTDTWTMVAPLS 690



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 28/93 (30%), Positives = 48/93 (51%)
 Frame = +2

Query: 329 FGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLY 508
           FG AV+    L++ GG+D ++ ++  V  YN +T  W   P M   RH  G  V+   +Y
Sbjct: 502 FGVAVIDD-KLFVIGGRDGLK-TLNTVECYNPKTKTWTVLPPMSTHRHGLGVTVLEGPIY 559

Query: 509 VAGGECEGIQRTLRSAEVYNPNRNRWSCISEMN 607
             GG  +G    L + E ++P   +W+ ++ M+
Sbjct: 560 AVGGH-DG-WSYLNTVERWDPQSQQWTYVASMS 590

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>KLH14_CHICK (Q5F3N5) Kelch-like protein 14|
          Length = 622

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 37/119 (31%), Positives = 56/119 (47%), Gaps = 4/119 (3%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRH----VVFYNTR 427
           +D   + W+ L  +P  Y+ A    C V    +L++ GG+D    + +H    V  Y+ R
Sbjct: 339 YDDEKKTWKILTIMP--YNSA--HHCVVEVENFLFVLGGEDQWNPNGKHSTNFVSRYDPR 394

Query: 428 TNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEM 604
            N W + P M  +R  F +C ++  LYV GG  E     L S E YN   N W  +S +
Sbjct: 395 FNSWIQLPPMQERRASFYACRLDKNLYVIGGRNE--TGYLSSVECYNLETNEWRYVSSL 451



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 31/117 (26%), Positives = 51/117 (43%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           +DP    W  LPP+  +   A  + C +     LY+ GG++   G +  V  YN  TN+W
Sbjct: 391 YDPRFNSWIQLPPM--QERRASFYACRLDKN--LYVIGGRNET-GYLSSVECYNLETNEW 445

Query: 440 YRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMNT 610
                + +        V N  +Y++GG   G    +     Y+P  + W+   +MNT
Sbjct: 446 RYVSSLPQPLAAHAGAVHNGKIYISGGVHNG--EYVPWLYCYDPVMDVWARKQDMNT 500



 Score = 30.8 bits (68), Expect = 3.3
 Identities = 18/62 (29%), Positives = 30/62 (48%), Gaps = 2/62 (3%)
 Frame = +2

Query: 416 YNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGG-ECEGIQR-TLRSAEVYNPNRNRWS 589
           Y+   + W R  DM  KR +    V+N+ LY  GG   +G     +   E Y+P  ++W+
Sbjct: 485 YDPVMDVWARKQDMNTKRAIHTLAVMNDRLYAIGGNHLKGFSHLDVMLVECYDPKGDQWN 544

Query: 590 CI 595
            +
Sbjct: 545 IL 546

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>KLD7B_HUMAN (Q96G42) Kelch domain-containing protein 7B|
          Length = 495

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 41/125 (32%), Positives = 51/125 (40%), Gaps = 13/125 (10%)
 Frame = +2

Query: 254 HAFDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGC-------YLYLFGGKDPVRGS----- 397
           H F+P    WR L  VP E         A L GC       YL+L GG   +RGS     
Sbjct: 224 HVFNPRENTWRPLTQVPEE---------APLRGCGLCTMHNYLFLAGG---IRGSGAKAV 271

Query: 398 -MRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPN 574
               V  YN  TN W +   M + R       ++  LY  GGEC      L S E Y+P 
Sbjct: 272 CSNEVFCYNPLTNIWSQVRPMQQARAQLKLVALDGLLYAIGGEC------LYSMECYDPR 325

Query: 575 RNRWS 589
            + W+
Sbjct: 326 TDAWT 330

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>KEAP1_MOUSE (Q9Z2X8) Kelch-like ECH-associated protein 1 (Cytosolic inhibitor|
           of Nrf2)
          Length = 624

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 36/95 (37%), Positives = 47/95 (49%), Gaps = 2/95 (2%)
 Frame = +2

Query: 332 GCAVLSGCYLYLFGGKDPVRGSMRH--VVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCL 505
           G  V+ G ++Y  GG     G + H  V  Y    ++W+    ML +R   G  V+N  L
Sbjct: 417 GVGVIDG-HIYAVGGS---HGCIHHSSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLL 472

Query: 506 YVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMNT 610
           Y  GG  +G  R L SAE Y P RN W  I+ MNT
Sbjct: 473 YAVGG-FDGTNR-LNSAECYYPERNEWRMITPMNT 505



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 36/115 (31%), Positives = 53/115 (46%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           ++P    W  + P+    +  +G G AVL+   LY  GG D          +Y  R N+W
Sbjct: 443 YEPERDEWHLVAPM---LTRRIGVGVAVLNRL-LYAVGGFDGTNRLNSAECYYPER-NEW 497

Query: 440 YRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEM 604
                M   R   G CV++NC+Y AGG  +G Q  L S E Y+     W+ ++ M
Sbjct: 498 RMITPMNTIRSGAGVCVLHNCIYAAGG-YDG-QDQLNSVERYDVETETWTFVAPM 550



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 37/122 (30%), Positives = 52/122 (42%)
 Frame = +2

Query: 248 SWHAFDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTR 427
           S   + P    WR + P+    S   G G  VL  C +Y  GG D  +  +  V  Y+  
Sbjct: 486 SAECYYPERNEWRMITPMNTIRS---GAGVCVLHNC-IYAAGGYDG-QDQLNSVERYDVE 540

Query: 428 TNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMN 607
           T  W     M   R   G  V    +YV GG  +G    L S E Y+P+ + WS ++ M 
Sbjct: 541 TETWTFVAPMRHHRSALGITVHQGKIYVLGGY-DG-HTFLDSVECYDPDSDTWSEVTRMT 598

Query: 608 TG 613
           +G
Sbjct: 599 SG 600



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 38/128 (29%), Positives = 54/128 (42%), Gaps = 4/128 (3%)
 Frame = +2

Query: 239 QKLSW-HAFDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPV---RGSMRH 406
           Q LS+  A++P +  W  L  +    S   G  C V  G  LY  GG++           
Sbjct: 337 QSLSYLEAYNPSNGSWLRLADLQVPRSGLAG--CVV--GGLLYAVGGRNNSPDGNTDSSA 392

Query: 407 VVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRW 586
           +  YN  TN+W     M   R+  G  VI+  +Y  GG    I  +  S E Y P R+ W
Sbjct: 393 LDCYNPMTNQWSPCASMSVPRNRIGVGVIDGHIYAVGGSHGCIHHS--SVERYEPERDEW 450

Query: 587 SCISEMNT 610
             ++ M T
Sbjct: 451 HLVAPMLT 458



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 26/88 (29%), Positives = 37/88 (42%), Gaps = 2/88 (2%)
 Frame = +2

Query: 350 GCYLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECE 529
           G  +Y  GG    R S+ ++  YN     W R  D+   R     CV+   LY  GG   
Sbjct: 325 GRLIYTAGGY--FRQSLSYLEAYNPSNGSWLRLADLQVPRSGLAGCVVGGLLYAVGGRNN 382

Query: 530 GIQRTLRSA--EVYNPNRNRWSCISEMN 607
                  S+  + YNP  N+WS  + M+
Sbjct: 383 SPDGNTDSSALDCYNPMTNQWSPCASMS 410

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>KLH14_HUMAN (Q9P2G3) Kelch-like protein 14|
          Length = 628

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 37/119 (31%), Positives = 56/119 (47%), Gaps = 4/119 (3%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRH----VVFYNTR 427
           +D   + W+ L  +P  Y+ A    C V    +L++ GG+D    + +H    V  Y+ R
Sbjct: 345 YDDEKKTWKILTIMP--YNSA--HHCVVEVENFLFVLGGEDQWNPNGKHSTNFVSRYDPR 400

Query: 428 TNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEM 604
            N W + P M  +R  F +C ++  LYV GG  E     L S E YN   N W  +S +
Sbjct: 401 FNSWIQLPPMQERRASFYACRLDKHLYVIGGRNE--TGYLSSVECYNLETNEWRYVSSL 457



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 31/117 (26%), Positives = 52/117 (44%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           +DP    W  LPP+  +   A  + C +    +LY+ GG++   G +  V  YN  TN+W
Sbjct: 397 YDPRFNSWIQLPPM--QERRASFYACRLDK--HLYVIGGRNET-GYLSSVECYNLETNEW 451

Query: 440 YRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMNT 610
                + +        V N  +Y++GG   G    +     Y+P  + W+   +MNT
Sbjct: 452 RYVSSLPQPLAAHAGAVHNGKIYISGGVHNG--EYVPWLYCYDPVMDVWARKQDMNT 506

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>KEAP1_RAT (P57790) Kelch-like ECH-associated protein 1 (Cytosolic inhibitor|
           of Nrf2) (INrf2)
          Length = 624

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 36/95 (37%), Positives = 47/95 (49%), Gaps = 2/95 (2%)
 Frame = +2

Query: 332 GCAVLSGCYLYLFGGKDPVRGSMRH--VVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCL 505
           G  V+ G ++Y  GG     G + H  V  Y    ++W+    ML +R   G  V+N  L
Sbjct: 417 GGGVIDG-HIYAVGGS---HGCIHHSSVERYEPDRDEWHLVAPMLTRRIGVGVAVLNRLL 472

Query: 506 YVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMNT 610
           Y  GG  +G  R L SAE Y P RN W  I+ MNT
Sbjct: 473 YAVGG-FDGTNR-LNSAECYYPERNEWRMITPMNT 505



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 36/122 (29%), Positives = 53/122 (43%)
 Frame = +2

Query: 248 SWHAFDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTR 427
           S   + P    WR + P+    S   G G  VL  C +Y  GG D  +  +  V  Y+  
Sbjct: 486 SAECYYPERNEWRMITPMNTIRS---GAGVCVLHSC-IYAAGGYDG-QDQLNSVERYDVE 540

Query: 428 TNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMN 607
           T  W     M  +R   G  V    +YV GG  +G    L S E Y+P+ + WS ++ + 
Sbjct: 541 TETWTFVASMKHRRSALGIAVHQGRIYVLGGY-DG-HTFLDSVECYDPDTDTWSEVTRLT 598

Query: 608 TG 613
           +G
Sbjct: 599 SG 600



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 35/115 (30%), Positives = 53/115 (46%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           ++P    W  + P+    +  +G G AVL+   LY  GG D          +Y  R N+W
Sbjct: 443 YEPDRDEWHLVAPM---LTRRIGVGVAVLNRL-LYAVGGFDGTNRLNSAECYYPER-NEW 497

Query: 440 YRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEM 604
                M   R   G CV+++C+Y AGG  +G Q  L S E Y+     W+ ++ M
Sbjct: 498 RMITPMNTIRSGAGVCVLHSCIYAAGG-YDG-QDQLNSVERYDVETETWTFVASM 550



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 37/128 (28%), Positives = 55/128 (42%), Gaps = 4/128 (3%)
 Frame = +2

Query: 239 QKLSW-HAFDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPV---RGSMRH 406
           Q LS+  A++P +  W  L  +    S   G  C V  G  LY  GG++           
Sbjct: 337 QSLSYLEAYNPSNGSWLRLADLQVPRSGLAG--CVV--GGLLYAVGGRNNSPDGNTDSSA 392

Query: 407 VVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRW 586
           +  YN  TN+W     +   R+  G  VI+  +Y  GG    I  +  S E Y P+R+ W
Sbjct: 393 LDCYNPMTNQWSPCASLSVPRNRSGGGVIDGHIYAVGGSHGCIHHS--SVERYEPDRDEW 450

Query: 587 SCISEMNT 610
             ++ M T
Sbjct: 451 HLVAPMLT 458



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 25/82 (30%), Positives = 34/82 (41%), Gaps = 2/82 (2%)
 Frame = +2

Query: 350 GCYLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECE 529
           G  +Y  GG    R S+ ++  YN     W R  D+   R     CV+   LY  GG   
Sbjct: 325 GRLIYTAGGY--FRQSLSYLEAYNPSNGSWLRLADLQVPRSGLAGCVVGGLLYAVGGRNN 382

Query: 530 GIQRTLRSA--EVYNPNRNRWS 589
                  S+  + YNP  N+WS
Sbjct: 383 SPDGNTDSSALDCYNPMTNQWS 404

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>KLHL7_CHICK (Q5ZI33) Kelch-like protein 7|
          Length = 586

 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 36/119 (30%), Positives = 51/119 (42%), Gaps = 4/119 (3%)
 Frame = +2

Query: 260 FDPVHQLWRSL--PPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTN 433
           ++ V   W S   PP P +   A    CA      +Y  GG +    ++     Y+TRT 
Sbjct: 355 YNVVKDSWYSKLGPPTPRDSLAA----CAAEGK--IYTSGGSEVGNSALYLFECYDTRTE 408

Query: 434 KWYRAPDMLRKRHLFGSCVINNCLYVAGGECEG--IQRTLRSAEVYNPNRNRWSCISEM 604
            W+  P ML +R   G    N  +YV GG       +R L S EVY+P    W+ +  M
Sbjct: 409 SWHTKPSMLTQRCSHGMVEANGLIYVCGGSLGNNVSRRVLNSCEVYDPATETWTELCPM 467



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 18/53 (33%), Positives = 29/53 (54%)
 Frame = +2

Query: 281 WRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           W+ + P+P    + V   CA + G  +Y+  G   V G + H++ YNT T+KW
Sbjct: 508 WKMVSPMP---WKGVTVKCAAV-GSIVYVLAGFQGV-GRLGHILEYNTETDKW 555



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 28/119 (23%), Positives = 51/119 (42%)
 Frame = +2

Query: 248 SWHAFDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTR 427
           S   +DP  + W  L P+     EA      V     ++  GG++ + G + +V +Y+ +
Sbjct: 450 SCEVYDPATETWTELCPM----IEARKNHGLVFVKDKIFAVGGQNGL-GGLDNVEYYDIK 504

Query: 428 TNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEM 604
            N+W     M  K        + + +YV  G  +G+ R     E YN   ++W   S++
Sbjct: 505 MNEWKMVSPMPWKGVTVKCAAVGSIVYVLAG-FQGVGRLGHILE-YNTETDKWIANSKV 561

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>KLHL8_MOUSE (P59280) Kelch-like protein 8|
          Length = 629

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 32/104 (30%), Positives = 49/104 (47%)
 Frame = +2

Query: 299 VPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLF 478
           V P  +   G G   L   ++Y  GG D V  S+  V  Y+   +KW    +M ++R   
Sbjct: 452 VAPMNTPRGGVGSVALIN-HVYAVGGNDGV-ASLSSVERYHPHLDKWIEVKEMGQRRAGN 509

Query: 479 GSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMNT 610
           G   ++ CLYV GG  +     L S E Y+P  N+W  ++ + T
Sbjct: 510 GVSELHGCLYVVGGFDD--NSPLSSVERYDPRSNKWDYVAALTT 551



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 24/84 (28%), Positives = 40/84 (47%)
 Frame = +2

Query: 359 LYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQ 538
           L+  GG+       R +  Y+   N W+  P+M  +R   G   +   +Y  GG  +G +
Sbjct: 329 LFCVGGRGGSGDPFRSIECYSINKNSWFFGPEMNSRRRHVGVISVEGKVYAVGGH-DGNE 387

Query: 539 RTLRSAEVYNPNRNRWSCISEMNT 610
             L S E+++P  N+W   + MNT
Sbjct: 388 H-LGSMEMFDPLTNKWMMKASMNT 410



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 33/119 (27%), Positives = 52/119 (43%)
 Frame = +2

Query: 248 SWHAFDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTR 427
           S   FDP+   W     +    ++  G   A L G  +Y  GG D        V  Y+  
Sbjct: 391 SMEMFDPLTNKWMMKASMN---TKRRGIALASLGGP-IYAIGGLDD-NTCFSDVERYDIE 445

Query: 428 TNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEM 604
           +++W     M   R   GS  + N +Y  GG  +G+  +L S E Y+P+ ++W  + EM
Sbjct: 446 SDQWSTVAPMNTPRGGVGSVALINHVYAVGGN-DGV-ASLSSVERYHPHLDKWIEVKEM 502



 Score = 37.4 bits (85), Expect = 0.035
 Identities = 25/94 (26%), Positives = 41/94 (43%)
 Frame = +2

Query: 326 GFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCL 505
           G G + L GC LY+ GG D     +  V  Y+ R+NKW     +   R   G   +   +
Sbjct: 508 GNGVSELHGC-LYVVGGFDD-NSPLSSVERYDPRSNKWDYVAALTTPRGGVGIATVMGKI 565

Query: 506 YVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMN 607
           +  GG        L + E ++P  N+W  +  ++
Sbjct: 566 FAVGG--HNGNAYLNTVEAFDPVLNKWELVGPVS 597



 Score = 32.7 bits (73), Expect = 0.86
 Identities = 24/86 (27%), Positives = 35/86 (40%), Gaps = 2/86 (2%)
 Frame = +2

Query: 359 LYLFGGKDPVR--GSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEG 532
           +Y  GG D     GSM     ++  TNKW     M  KR       +   +Y  GG  + 
Sbjct: 377 VYAVGGHDGNEHLGSME---MFDPLTNKWMMKASMNTKRRGIALASLGGPIYAIGGLDDN 433

Query: 533 IQRTLRSAEVYNPNRNRWSCISEMNT 610
                   E Y+   ++WS ++ MNT
Sbjct: 434 T--CFSDVERYDIESDQWSTVAPMNT 457

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>KLHL7_RAT (Q5XHZ6) Kelch-like protein 7|
          Length = 586

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 36/119 (30%), Positives = 50/119 (42%), Gaps = 4/119 (3%)
 Frame = +2

Query: 260 FDPVHQLWRSL--PPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTN 433
           ++ V   W S   PP P +   A    CA      +Y  GG +    ++     Y+TRT 
Sbjct: 355 YNVVKDSWYSKLGPPTPRDSLAA----CAAEGK--IYTSGGSEVGNSALYLFECYDTRTE 408

Query: 434 KWYRAPDMLRKRHLFGSCVINNCLYVAGGECEG--IQRTLRSAEVYNPNRNRWSCISEM 604
            W+  P ML +R   G    N  +YV GG        R L S EVY+P    W+ +  M
Sbjct: 409 SWHTKPSMLTQRCSHGMVEANGLIYVCGGSLGNNVSGRVLSSCEVYDPATETWTELCSM 467



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 18/53 (33%), Positives = 28/53 (52%)
 Frame = +2

Query: 281 WRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           W+ + P+P      V   CA + G  +Y+  G   V G + H++ YNT T+KW
Sbjct: 508 WKMVSPMP---WRGVTVKCAAV-GSVIYVLAGFQGV-GRLGHILEYNTETDKW 555



 Score = 29.3 bits (64), Expect = 9.5
 Identities = 25/120 (20%), Positives = 51/120 (42%), Gaps = 1/120 (0%)
 Frame = +2

Query: 248 SWHAFDPVHQLWRSL-PPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNT 424
           S   +DP  + W  L   + P  +  +     V     ++  GG++ + G + +V +Y+ 
Sbjct: 450 SCEVYDPATETWTELCSMIEPRKNHGL-----VFVKDKIFAVGGQNGL-GGLDNVEYYDI 503

Query: 425 RTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEM 604
           + N+W     M  +        + + +YV  G  +G+ R     E YN   ++W   S++
Sbjct: 504 KLNEWKMVSPMPWRGVTVKCAAVGSVIYVLAG-FQGVGRLGHILE-YNTETDKWVANSKV 561

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>KLHL7_MOUSE (Q8BUL5) Kelch-like protein 7|
          Length = 586

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 36/119 (30%), Positives = 50/119 (42%), Gaps = 4/119 (3%)
 Frame = +2

Query: 260 FDPVHQLWRSL--PPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTN 433
           ++ V   W S   PP P +   A    CA      +Y  GG +    ++     Y+TRT 
Sbjct: 355 YNVVKDSWYSKLGPPTPRDSLAA----CAAEGK--IYTSGGSEVGNSALYLFECYDTRTE 408

Query: 434 KWYRAPDMLRKRHLFGSCVINNCLYVAGGECEG--IQRTLRSAEVYNPNRNRWSCISEM 604
            W+  P ML +R   G    N  +YV GG        R L S EVY+P    W+ +  M
Sbjct: 409 SWHTKPSMLTQRCSHGMVEANGLIYVCGGSLGNNVSGRVLSSCEVYDPATETWTELCSM 467



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 18/53 (33%), Positives = 28/53 (52%)
 Frame = +2

Query: 281 WRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           W+ + P+P      V   CA + G  +Y+  G   V G + H++ YNT T+KW
Sbjct: 508 WKMVSPMP---WRGVTVKCAAV-GSVIYVLAGFQGV-GRLGHILEYNTETDKW 555



 Score = 29.3 bits (64), Expect = 9.5
 Identities = 25/120 (20%), Positives = 51/120 (42%), Gaps = 1/120 (0%)
 Frame = +2

Query: 248 SWHAFDPVHQLWRSL-PPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNT 424
           S   +DP  + W  L   + P  +  +     V     ++  GG++ + G + +V +Y+ 
Sbjct: 450 SCEVYDPATETWTELCSMIEPRKNHGL-----VFVKDKIFAVGGQNGL-GGLDNVEYYDI 503

Query: 425 RTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEM 604
           + N+W     M  +        + + +YV  G  +G+ R     E YN   ++W   S++
Sbjct: 504 KLNEWKMVSPMPWRGVTVKCAAVGSVIYVLAG-FQGVGRLGHILE-YNTETDKWIANSKV 561

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>KLHL7_HUMAN (Q8IXQ5) Kelch-like protein 7|
          Length = 586

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 36/119 (30%), Positives = 50/119 (42%), Gaps = 4/119 (3%)
 Frame = +2

Query: 260 FDPVHQLWRSL--PPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTN 433
           ++ V   W S   PP P +   A    CA      +Y  GG +    ++     Y+TRT 
Sbjct: 355 YNVVKDSWYSKLGPPTPRDSLAA----CAAEGK--IYTSGGSEVGNSALYLFECYDTRTE 408

Query: 434 KWYRAPDMLRKRHLFGSCVINNCLYVAGGECEG--IQRTLRSAEVYNPNRNRWSCISEM 604
            W+  P ML +R   G    N  +YV GG        R L S EVY+P    W+ +  M
Sbjct: 409 SWHTKPSMLTQRCSHGMVEANGLIYVCGGSLGNNVSGRVLNSCEVYDPATETWTELCPM 467



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 18/53 (33%), Positives = 29/53 (54%)
 Frame = +2

Query: 281 WRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           W+ + P+P    + V   CA + G  +Y+  G   V G + H++ YNT T+KW
Sbjct: 508 WKMVSPMP---WKGVTVKCAAV-GSIVYVLAGFQGV-GRLGHILEYNTETDKW 555



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 28/119 (23%), Positives = 51/119 (42%)
 Frame = +2

Query: 248 SWHAFDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTR 427
           S   +DP  + W  L P+     EA      V     ++  GG++ + G + +V +Y+ +
Sbjct: 450 SCEVYDPATETWTELCPM----IEARKNHGLVFVKDKIFAVGGQNGL-GGLDNVEYYDIK 504

Query: 428 TNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEM 604
            N+W     M  K        + + +YV  G  +G+ R     E YN   ++W   S++
Sbjct: 505 LNEWKMVSPMPWKGVTVKCAAVGSIVYVLAG-FQGVGRLGHILE-YNTETDKWVANSKV 561

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>KBTBB_MOUSE (Q8BNW9) Kelch repeat and BTB domain-containing protein 11|
          Length = 633

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 36/116 (31%), Positives = 51/116 (43%), Gaps = 5/116 (4%)
 Frame = +2

Query: 281 WRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMR-----HVVFYNTRTNKWYR 445
           WR L  +P E + A G G  VL   YL++ GG  P     R      V  YN  T+ W  
Sbjct: 343 WRELTRLP-EGAPARGCGLCVLFN-YLFVAGGVAPAGPDGRARPSDQVYCYNPVTDSWST 400

Query: 446 APDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMNTG 613
              + + R       ++  LY  GGEC      L S E Y+P  +RW+ ++ +  G
Sbjct: 401 VRPLRQARSQVQLLALDGHLYAVGGEC------LLSVERYDPRADRWTAVAPLPRG 450

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>KBTBB_HUMAN (O94819) Kelch repeat and BTB domain-containing protein 11 (Kelch|
           domain-containing protein 7B)
          Length = 623

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 36/116 (31%), Positives = 51/116 (43%), Gaps = 5/116 (4%)
 Frame = +2

Query: 281 WRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMR-----HVVFYNTRTNKWYR 445
           WR L  +P E + A G G  VL   YL++ GG  P     R      V  YN  T+ W  
Sbjct: 337 WRELTRLP-EGAPARGCGLCVLYN-YLFVAGGVAPAGPDGRARPSDQVFCYNPATDSWSA 394

Query: 446 APDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMNTG 613
              + + R       ++  LY  GGEC      L S E Y+P  +RW+ ++ +  G
Sbjct: 395 VRPLRQARSQLRLLALDGHLYAVGGEC------LLSVERYDPRADRWAPVAPLPRG 444

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>KLHL8_HUMAN (Q9P2G9) Kelch-like protein 8|
          Length = 620

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 31/104 (29%), Positives = 50/104 (48%)
 Frame = +2

Query: 299 VPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLF 478
           V P  +   G G   L   ++Y  GG D +  S+  V  Y+   +KW    +M ++R   
Sbjct: 443 VAPMNTPRGGVGSVALVN-HVYAVGGNDGM-ASLSSVERYDPHLDKWIEVKEMGQRRAGN 500

Query: 479 GSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMNT 610
           G   ++ CLYV GG  +  +  L S E Y+P  N+W  ++ + T
Sbjct: 501 GVSKLHGCLYVVGGFDDNSR--LSSVERYDPRSNKWDYVAALTT 542



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 24/84 (28%), Positives = 40/84 (47%)
 Frame = +2

Query: 359 LYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQ 538
           L+  GG+       R +  Y+   N W+  P+M  +R   G   +   +Y  GG  +G +
Sbjct: 320 LFCVGGRGGSGDPFRSIECYSINKNSWFFGPEMNSRRRHVGVISVEGKVYAVGGH-DGNE 378

Query: 539 RTLRSAEVYNPNRNRWSCISEMNT 610
             L S E+++P  N+W   + MNT
Sbjct: 379 H-LGSMEMFDPLTNKWMMKASMNT 401



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 26/94 (27%), Positives = 41/94 (43%)
 Frame = +2

Query: 326 GFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCL 505
           G G + L GC LY+ GG D     +  V  Y+ R+NKW     +   R   G   +   +
Sbjct: 499 GNGVSKLHGC-LYVVGGFDD-NSRLSSVERYDPRSNKWDYVAALTTPRGGVGIATVMGKI 556

Query: 506 YVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMN 607
           +  GG        L + E ++P  NRW  +  ++
Sbjct: 557 FAVGG--HNGNAYLNTVEAFDPVLNRWELVGSVS 588



 Score = 38.5 bits (88), Expect = 0.016
 Identities = 33/119 (27%), Positives = 52/119 (43%)
 Frame = +2

Query: 248 SWHAFDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTR 427
           S   FDP+   W     +    ++  G   A L G  +Y  GG D        V  Y+  
Sbjct: 382 SMEMFDPLTNKWMMKASMN---TKRRGIALASLGGP-IYAIGGLDD-NTCFNDVERYDIE 436

Query: 428 TNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEM 604
           +++W     M   R   GS  + N +Y  GG  +G+  +L S E Y+P+ ++W  + EM
Sbjct: 437 SDQWSTVAPMNTPRGGVGSVALVNHVYAVGGN-DGM-ASLSSVERYDPHLDKWIEVKEM 493



 Score = 33.1 bits (74), Expect = 0.66
 Identities = 24/86 (27%), Positives = 35/86 (40%), Gaps = 2/86 (2%)
 Frame = +2

Query: 359 LYLFGGKDPVR--GSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEG 532
           +Y  GG D     GSM     ++  TNKW     M  KR       +   +Y  GG  + 
Sbjct: 368 VYAVGGHDGNEHLGSME---MFDPLTNKWMMKASMNTKRRGIALASLGGPIYAIGGLDDN 424

Query: 533 IQRTLRSAEVYNPNRNRWSCISEMNT 610
                   E Y+   ++WS ++ MNT
Sbjct: 425 T--CFNDVERYDIESDQWSTVAPMNT 448

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>BTBD5_MOUSE (Q9CR40) BTB/POZ domain-containing protein 5|
          Length = 571

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 36/107 (33%), Positives = 48/107 (44%)
 Frame = +2

Query: 284 RSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLR 463
           R   PV P  +    F  AVL G  LY  GG  P    M  V  Y+   + W     M  
Sbjct: 411 RQWQPVAPMTTTRSCFAAAVLDGM-LYAIGGYGPAH--MNSVERYDPSKDSWEMVAPMAD 467

Query: 464 KRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEM 604
           KR  FG  V+   ++V GG   G+   L S E Y+P++N+W+    M
Sbjct: 468 KRIHFGVGVMLGFIFVVGGH-NGVSH-LSSIERYDPHQNQWTVCRPM 512



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 29/109 (26%), Positives = 50/109 (45%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           +DP    W  + P+     + + FG  V+ G ++++ GG + V   +  +  Y+   N+W
Sbjct: 452 YDPSKDSWEMVAPMA---DKRIHFGVGVMLG-FIFVVGGHNGV-SHLSSIERYDPHQNQW 506

Query: 440 YRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRW 586
                M   R   G+ VI+N LYV GG        L + + Y+P  + W
Sbjct: 507 TVCRPMKEPRTGVGAAVIDNYLYVVGGHSG--SSYLNTVQKYDPISDTW 553



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 24/85 (28%), Positives = 41/85 (48%), Gaps = 6/85 (7%)
 Frame = +2

Query: 371 GGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQ--RT 544
           GGK  +   +  V  Y  + + W     +   R+ FG CV++  ++V GG    ++   T
Sbjct: 289 GGKSGLFACLDSVEMYFPQNDSWIGLAPLNIPRYEFGICVLDQKVFVIGGIETSVRPGMT 348

Query: 545 LR----SAEVYNPNRNRWSCISEMN 607
           +R    S E +NP+ N W+ +  MN
Sbjct: 349 VRKHENSVECWNPDTNTWTSLERMN 373

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>KBTBA_RAT (Q9ER30) Kelch repeat and BTB domain-containing protein 10|
           (Kelch-related protein 1) (Kel-like protein 23)
           (Sarcosin)
          Length = 606

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 41/138 (29%), Positives = 65/138 (47%), Gaps = 5/138 (3%)
 Frame = +2

Query: 212 VYVFKRDRDQKLSWHAF--DPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKD- 382
           +YV + ++DQ L  + F  D V   W  LPP+P   S    FG   +    +Y+  GKD 
Sbjct: 353 LYVDEENKDQPLQSYFFQLDNVSSEWVGLPPLP---SARCLFGLGEVDD-KIYVVAGKDL 408

Query: 383 PVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVI--NNCLYVAGGECEGIQRTLRSA 556
               S+  V+ Y+    KW    ++  K  ++G  VI  N  +Y  GG+ +  + T R  
Sbjct: 409 QTEASLDSVLCYDPVAAKWSEVKNLPIK--VYGHNVISHNGMIYCLGGKTDDKKCTNR-V 465

Query: 557 EVYNPNRNRWSCISEMNT 610
            +YNP +  W  ++ M T
Sbjct: 466 FIYNPKKGDWKDLAPMKT 483



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 38/149 (25%), Positives = 62/149 (41%), Gaps = 7/149 (4%)
 Frame = +2

Query: 176 SLRKKFGMAE--EWVYVFK-RDRDQKLSWHA---FDPVHQLWRSLPPVPPEYSEAVGFGC 337
           S R  FG+ E  + +YV   +D   + S  +   +DPV   W  +  +P +      +G 
Sbjct: 386 SARCLFGLGEVDDKIYVVAGKDLQTEASLDSVLCYDPVAAKWSEVKNLPIKV-----YGH 440

Query: 338 AVLS-GCYLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVA 514
            V+S    +Y  GGK   +     V  YN +   W     M   R +FG  +    + +A
Sbjct: 441 NVISHNGMIYCLGGKTDDKKCTNRVFIYNPKKGDWKDLAPMKTPRSMFGVAIHKGKIVIA 500

Query: 515 GGECEGIQRTLRSAEVYNPNRNRWSCISE 601
           GG  E       S E ++   N+W  ++E
Sbjct: 501 GGVTE--DGLSASVEAFDLKTNKWEVMTE 527

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>KLH12_XENLA (Q6NRH0) Kelch-like protein 12|
          Length = 564

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 34/119 (28%), Positives = 57/119 (47%), Gaps = 2/119 (1%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVR--GSMRHVVFYNTRTN 433
           +DP  Q W  LP +  +      +   V  G  +Y+ GG D      S+  + + +    
Sbjct: 298 YDPKTQEWSVLPSITRKRR----YVATVSLGDRVYVIGGYDGRSRLSSVECLDYTSEEDG 353

Query: 434 KWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMNT 610
            WY    M  +R L G+  + + +YV+GG  +G +R   S E Y+PN ++WS + +M T
Sbjct: 354 VWYSVAPMNVRRGLAGATTLGDMIYVSGG-FDGSRRH-TSMERYDPNIDQWSMLGDMQT 410



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 34/117 (29%), Positives = 54/117 (46%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           +DP    W  + P+  + S   G G ++L+  ++Y+ GG D     +  V  YN RT+ W
Sbjct: 442 YDPHTGHWSHVTPMATKRS---GAGVSLLND-HIYVVGGFDGT-AHLSSVEAYNIRTDSW 496

Query: 440 YRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMNT 610
                M   R   G+ V+   LY   G  +G    L S E Y+P  + W+ ++ M T
Sbjct: 497 TTMTSMTTPRCYVGATVLRGRLYAIAG-YDG-NSLLNSVECYDPLIDSWAVVTSMAT 551



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 35/121 (28%), Positives = 52/121 (42%)
 Frame = +2

Query: 248 SWHAFDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTR 427
           S   +DP    W  L  +    +   G G  V +G  +Y  GG D +   +  V  Y+  
Sbjct: 391 SMERYDPNIDQWSMLGDMQ---TAREGAGLVVANGV-IYCLGGYDGLN-ILSSVERYDPH 445

Query: 428 TNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMN 607
           T  W     M  KR   G  ++N+ +YV GG  +G    L S E YN   + W+ ++ M 
Sbjct: 446 TGHWSHVTPMATKRSGAGVSLLNDHIYVVGG-FDGTAH-LSSVEAYNIRTDSWTTMTSMT 503

Query: 608 T 610
           T
Sbjct: 504 T 504



 Score = 29.6 bits (65), Expect = 7.2
 Identities = 15/54 (27%), Positives = 26/54 (48%)
 Frame = +2

Query: 359 LYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGG 520
           L + GG    +  +  V  Y+ +T +W   P + RKR    +  + + +YV GG
Sbjct: 279 LLVIGGFGSQQSPIDIVEKYDPKTQEWSVLPSITRKRRYVATVSLGDRVYVIGG 332

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>BTBD5_HUMAN (Q9NXS3) BTB/POZ domain-containing protein 5|
          Length = 571

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 35/107 (32%), Positives = 48/107 (44%)
 Frame = +2

Query: 284 RSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLR 463
           R   PV P  +    F  AVL G  +Y  GG  P    M  V  Y+   + W     M  
Sbjct: 411 RKWQPVAPMTTTRSCFAAAVLDGM-IYAIGGYGPAH--MNSVERYDPSKDSWEMVASMAD 467

Query: 464 KRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEM 604
           KR  FG  V+   ++V GG   G+   L S E Y+P++N+W+    M
Sbjct: 468 KRIHFGVGVMLGFIFVVGGH-NGVSH-LSSIERYDPHQNQWTVCRPM 512



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 25/85 (29%), Positives = 41/85 (48%), Gaps = 6/85 (7%)
 Frame = +2

Query: 371 GGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQR--T 544
           GGK  +   +  V  Y  + + W     +   R+ FG CV++  +YV GG    ++   T
Sbjct: 289 GGKSGLFACLDSVEMYFPQNDSWIGLAPLNIPRYEFGICVLDQKVYVIGGIATNVRPGVT 348

Query: 545 LR----SAEVYNPNRNRWSCISEMN 607
           +R    S E +NP+ N W+ +  MN
Sbjct: 349 IRKHENSVECWNPDTNTWTSLERMN 373



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 28/109 (25%), Positives = 49/109 (44%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           +DP    W  +  +     + + FG  V+ G ++++ GG + V   +  +  Y+   N+W
Sbjct: 452 YDPSKDSWEMVASMA---DKRIHFGVGVMLG-FIFVVGGHNGV-SHLSSIERYDPHQNQW 506

Query: 440 YRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRW 586
                M   R   G+ VI+N LYV GG        L + + Y+P  + W
Sbjct: 507 TVCRPMKEPRTGVGAAVIDNYLYVVGGHSG--SSYLNTVQKYDPISDTW 553

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>KLH12_BRARE (Q5U374) Kelch-like protein 12|
          Length = 564

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 37/121 (30%), Positives = 53/121 (43%)
 Frame = +2

Query: 248 SWHAFDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTR 427
           S   +DP    W  L  +    +   G G  V SG  +Y  GG D +   +  V  Y+  
Sbjct: 391 SMERYDPNIDQWSMLGDMQ---TAREGAGLVVASGL-IYCLGGYDGLN-ILNSVERYDPH 445

Query: 428 TNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMN 607
           T  W     M  KR   G  ++N+ +YV GG  +G    L S EVYN   + W+ ++ M 
Sbjct: 446 TGHWTSVTPMANKRSGAGVALLNDHIYVVGG-FDGTAH-LSSVEVYNIRTDYWTTVANMT 503

Query: 608 T 610
           T
Sbjct: 504 T 504



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 33/119 (27%), Positives = 55/119 (46%), Gaps = 2/119 (1%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVR--GSMRHVVFYNTRTN 433
           +DP  + W  LP +  +      +   V     +Y+ GG D      S+  + +      
Sbjct: 298 YDPKTREWSFLPNIARKRR----YVATVALNDRVYVIGGYDGRSRLSSVECLDYTADEDG 353

Query: 434 KWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMNT 610
            WY    M  +R L G+  + + +YVAGG  +G +R   S E Y+PN ++WS + +M T
Sbjct: 354 VWYSVATMNVRRGLAGATTLGDMIYVAGG-FDGSRRH-TSMERYDPNIDQWSMLGDMQT 410



 Score = 33.1 bits (74), Expect = 0.66
 Identities = 16/54 (29%), Positives = 28/54 (51%)
 Frame = +2

Query: 359 LYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGG 520
           L + GG    +  +  V  Y+ +T +W   P++ RKR    +  +N+ +YV GG
Sbjct: 279 LLVIGGFGSQQSPIDIVEKYDPKTREWSFLPNIARKRRYVATVALNDRVYVIGG 332

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>KLH12_RAT (Q8R2H4) Kelch-like protein 12 (CUL3-interacting protein 1)|
          Length = 568

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 35/117 (29%), Positives = 54/117 (46%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           +DP    W ++ P+  + S   G G A+L+  ++Y+ GG D     +  V  YN RT+ W
Sbjct: 446 YDPHTGHWTNVTPMATKRS---GAGVALLND-HIYVVGGFDGT-AHLSSVEAYNIRTDSW 500

Query: 440 YRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMNT 610
                M   R   G+ V+   LY   G  +G    L S E Y+P  + W  ++ M T
Sbjct: 501 TTVTSMTTPRCYVGATVLRGRLYAIAG-YDG-NSLLSSIECYDPIIDSWEVVASMGT 555



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 36/121 (29%), Positives = 52/121 (42%)
 Frame = +2

Query: 248 SWHAFDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTR 427
           S   +DP    W  L  +    +   G G  V SG  +Y  GG D +   +  V  Y+  
Sbjct: 395 SMERYDPNIDQWSMLGDMQ---TAREGAGLVVASGI-IYCLGGYDGLN-ILNSVEKYDPH 449

Query: 428 TNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMN 607
           T  W     M  KR   G  ++N+ +YV GG  +G    L S E YN   + W+ ++ M 
Sbjct: 450 TGHWTNVTPMATKRSGAGVALLNDHIYVVGG-FDGTAH-LSSVEAYNIRTDSWTTVTSMT 507

Query: 608 T 610
           T
Sbjct: 508 T 508



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 33/119 (27%), Positives = 56/119 (47%), Gaps = 2/119 (1%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVR--GSMRHVVFYNTRTN 433
           +DP  Q W  LP +  +      +  +V     +Y+ GG D      S+  + +      
Sbjct: 302 YDPKTQEWSFLPSITRKRR----YVASVSLHDRIYVIGGYDGRSRLSSVECLDYTADEDG 357

Query: 434 KWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMNT 610
            WY    M  +R L G+  + + +YV+GG  +G +R   S E Y+PN ++WS + +M T
Sbjct: 358 VWYSVAPMNVRRGLAGATTLGDMIYVSGG-FDGSRRH-TSMERYDPNIDQWSMLGDMQT 414



 Score = 31.2 bits (69), Expect = 2.5
 Identities = 16/54 (29%), Positives = 27/54 (50%)
 Frame = +2

Query: 359 LYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGG 520
           L + GG    +  +  V  Y+ +T +W   P + RKR    S  +++ +YV GG
Sbjct: 283 LLVVGGFGSQQSPIDVVEKYDPKTQEWSFLPSITRKRRYVASVSLHDRIYVIGG 336

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>KLH12_MOUSE (Q8BZM0) Kelch-like protein 12 (CUL3-interacting protein 1)|
          Length = 568

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 35/117 (29%), Positives = 54/117 (46%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           +DP    W ++ P+  + S   G G A+L+  ++Y+ GG D     +  V  YN RT+ W
Sbjct: 446 YDPHTGHWTNVTPMATKRS---GAGVALLND-HIYVVGGFDGT-AHLSSVEAYNIRTDSW 500

Query: 440 YRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMNT 610
                M   R   G+ V+   LY   G  +G    L S E Y+P  + W  ++ M T
Sbjct: 501 TTVTSMTTPRCYVGATVLRGRLYAIAG-YDG-NSLLSSIECYDPIIDSWEVVASMGT 555



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 36/121 (29%), Positives = 52/121 (42%)
 Frame = +2

Query: 248 SWHAFDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTR 427
           S   +DP    W  L  +    +   G G  V SG  +Y  GG D +   +  V  Y+  
Sbjct: 395 SMERYDPNIDQWSMLGDMQ---TAREGAGLVVASGI-IYCLGGYDGLN-ILNSVEKYDPH 449

Query: 428 TNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMN 607
           T  W     M  KR   G  ++N+ +YV GG  +G    L S E YN   + W+ ++ M 
Sbjct: 450 TGHWTNVTPMATKRSGAGVALLNDHIYVVGG-FDGTAH-LSSVEAYNIRTDSWTTVTSMT 507

Query: 608 T 610
           T
Sbjct: 508 T 508



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 33/119 (27%), Positives = 56/119 (47%), Gaps = 2/119 (1%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVR--GSMRHVVFYNTRTN 433
           +DP  Q W  LP +  +      +  +V     +Y+ GG D      S+  + +      
Sbjct: 302 YDPKTQEWSFLPSITRKRR----YVASVSLHDRIYVIGGYDGRSRLSSVECLDYTADEDG 357

Query: 434 KWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMNT 610
            WY    M  +R L G+  + + +YV+GG  +G +R   S E Y+PN ++WS + +M T
Sbjct: 358 VWYSVAPMNVRRGLAGATTLGDMIYVSGG-FDGSRRH-TSMERYDPNIDQWSMLGDMQT 414



 Score = 31.2 bits (69), Expect = 2.5
 Identities = 16/54 (29%), Positives = 27/54 (50%)
 Frame = +2

Query: 359 LYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGG 520
           L + GG    +  +  V  Y+ +T +W   P + RKR    S  +++ +YV GG
Sbjct: 283 LLVVGGFGSQQSPIDVVEKYDPKTQEWSFLPSITRKRRYVASVSLHDRIYVIGG 336

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>KLH12_HUMAN (Q53G59) Kelch-like protein 12 (CUL3-interacting protein 1)|
          Length = 568

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 35/117 (29%), Positives = 54/117 (46%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           +DP    W ++ P+  + S   G G A+L+  ++Y+ GG D     +  V  YN RT+ W
Sbjct: 446 YDPHTGHWTNVTPMATKRS---GAGVALLND-HIYVVGGFDGT-AHLSSVEAYNIRTDSW 500

Query: 440 YRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMNT 610
                M   R   G+ V+   LY   G  +G    L S E Y+P  + W  ++ M T
Sbjct: 501 TTVTSMTTPRCYVGATVLRGRLYAIAG-YDG-NSLLSSIECYDPIIDSWEVVTSMGT 555



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 36/121 (29%), Positives = 52/121 (42%)
 Frame = +2

Query: 248 SWHAFDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTR 427
           S   +DP    W  L  +    +   G G  V SG  +Y  GG D +   +  V  Y+  
Sbjct: 395 SMERYDPNIDQWSMLGDMQ---TAREGAGLVVASGV-IYCLGGYDGLN-ILNSVEKYDPH 449

Query: 428 TNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMN 607
           T  W     M  KR   G  ++N+ +YV GG  +G    L S E YN   + W+ ++ M 
Sbjct: 450 TGHWTNVTPMATKRSGAGVALLNDHIYVVGG-FDGTAH-LSSVEAYNIRTDSWTTVTSMT 507

Query: 608 T 610
           T
Sbjct: 508 T 508



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 33/119 (27%), Positives = 56/119 (47%), Gaps = 2/119 (1%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVR--GSMRHVVFYNTRTN 433
           +DP  Q W  LP +  +      +  +V     +Y+ GG D      S+  + +      
Sbjct: 302 YDPKTQEWSFLPSITRKRR----YVASVSLHDRIYVIGGYDGRSRLSSVECLDYTADEDG 357

Query: 434 KWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMNT 610
            WY    M  +R L G+  + + +YV+GG  +G +R   S E Y+PN ++WS + +M T
Sbjct: 358 VWYSVAPMNVRRGLAGATTLGDMIYVSGG-FDGSRRH-TSMERYDPNIDQWSMLGDMQT 414



 Score = 31.2 bits (69), Expect = 2.5
 Identities = 16/54 (29%), Positives = 27/54 (50%)
 Frame = +2

Query: 359 LYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGG 520
           L + GG    +  +  V  Y+ +T +W   P + RKR    S  +++ +YV GG
Sbjct: 283 LLVVGGFGSQQSPIDVVEKYDPKTQEWSFLPSITRKRRYVASVSLHDRIYVIGG 336

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>KLH10_RAT (Q6JEL3) Kelch-like protein 10|
          Length = 608

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 37/122 (30%), Positives = 55/122 (45%), Gaps = 5/122 (4%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDP-VRGSMRHVVFYNTRTNK 436
           FDPV + W  + P+   +S        VLS  ++Y  GG D  VR  +     Y   TN+
Sbjct: 359 FDPVKKTWHQVAPM---HSRRCYVSVTVLSN-FIYAMGGFDGYVR--LNTAERYEPETNQ 412

Query: 437 WYRAPDMLRKRHLFGSCVINNCLYVAGG----ECEGIQRTLRSAEVYNPNRNRWSCISEM 604
           W     M  +R    +  +   +Y+ GG    EC      L +AEVYN   N+W+ I+ M
Sbjct: 413 WTLIAPMHEQRSDASATTLYGKVYICGGFNGNEC------LFTAEVYNTESNQWTVIAPM 466

Query: 605 NT 610
            +
Sbjct: 467 RS 468



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 35/115 (30%), Positives = 50/115 (43%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           ++P    W  + P+  + S+A       L G  +Y+ GG +         V YNT +N+W
Sbjct: 406 YEPETNQWTLIAPMHEQRSDA---SATTLYG-KVYICGGFNGNECLFTAEV-YNTESNQW 460

Query: 440 YRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEM 604
                M  +R   G       +Y  GG  +G  R LRSAE Y+P  N W  I  M
Sbjct: 461 TVIAPMRSRRSGIGVIAYGEHVYAVGG-FDGANR-LRSAEAYSPVANTWRTIPTM 513



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 29/103 (28%), Positives = 44/103 (42%)
 Frame = +2

Query: 299 VPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLF 478
           + P  S   G G  +  G ++Y  GG D     +R    Y+   N W   P M   R  F
Sbjct: 463 IAPMRSRRSGIG-VIAYGEHVYAVGGFDGAN-RLRSAEAYSPVANTWRTIPTMFNPRSNF 520

Query: 479 GSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMN 607
           G  V+++ L+V GG   G   T  + E Y+   + W    +M+
Sbjct: 521 GIEVVDDLLFVVGG-FNGFTTTF-NVECYDEKTDEWYDAHDMS 561



 Score = 37.7 bits (86), Expect = 0.027
 Identities = 24/82 (29%), Positives = 41/82 (50%)
 Frame = +2

Query: 248 SWHAFDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTR 427
           S  A+ PV   WR++P +   ++    FG  V+    L++ GG +    +  +V  Y+ +
Sbjct: 496 SAEAYSPVANTWRTIPTM---FNPRSNFGIEVVDDL-LFVVGGFNGFTTTF-NVECYDEK 550

Query: 428 TNKWYRAPDMLRKRHLFGSCVI 493
           T++WY A DM   R     CV+
Sbjct: 551 TDEWYDAHDMSIYRSALSCCVV 572

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>KLH10_MOUSE (Q9D5V2) Kelch-like protein 10|
          Length = 608

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 37/122 (30%), Positives = 55/122 (45%), Gaps = 5/122 (4%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDP-VRGSMRHVVFYNTRTNK 436
           FDPV + W  + P+   +S        VLS  ++Y  GG D  VR  +     Y   TN+
Sbjct: 359 FDPVKKTWHQVAPM---HSRRCYVSVTVLSN-FIYAMGGFDGYVR--LNTAERYEPETNQ 412

Query: 437 WYRAPDMLRKRHLFGSCVINNCLYVAGG----ECEGIQRTLRSAEVYNPNRNRWSCISEM 604
           W     M  +R    +  +   +Y+ GG    EC      L +AEVYN   N+W+ I+ M
Sbjct: 413 WTLIAPMHEQRSDASATTLYGKVYICGGFNGNEC------LFTAEVYNTESNQWTVIAPM 466

Query: 605 NT 610
            +
Sbjct: 467 RS 468



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 35/115 (30%), Positives = 50/115 (43%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           ++P    W  + P+  + S+A       L G  +Y+ GG +         V YNT +N+W
Sbjct: 406 YEPETNQWTLIAPMHEQRSDA---SATTLYG-KVYICGGFNGNECLFTAEV-YNTESNQW 460

Query: 440 YRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEM 604
                M  +R   G       +Y  GG  +G  R LRSAE Y+P  N W  I  M
Sbjct: 461 TVIAPMRSRRSGIGVIAYGEHVYAVGG-FDGANR-LRSAEAYSPVANTWRTIPTM 513



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 29/103 (28%), Positives = 44/103 (42%)
 Frame = +2

Query: 299 VPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLF 478
           + P  S   G G  +  G ++Y  GG D     +R    Y+   N W   P M   R  F
Sbjct: 463 IAPMRSRRSGIG-VIAYGEHVYAVGGFDGAN-RLRSAEAYSPVANTWRTIPTMFNPRSNF 520

Query: 479 GSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMN 607
           G  V+++ L+V GG   G   T  + E Y+   + W    +M+
Sbjct: 521 GIEVVDDLLFVVGG-FNGFTTTF-NVECYDEKTDEWYDAHDMS 561



 Score = 37.7 bits (86), Expect = 0.027
 Identities = 24/82 (29%), Positives = 41/82 (50%)
 Frame = +2

Query: 248 SWHAFDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTR 427
           S  A+ PV   WR++P +   ++    FG  V+    L++ GG +    +  +V  Y+ +
Sbjct: 496 SAEAYSPVANTWRTIPTM---FNPRSNFGIEVVDDL-LFVVGGFNGFTTTF-NVECYDEK 550

Query: 428 TNKWYRAPDMLRKRHLFGSCVI 493
           T++WY A DM   R     CV+
Sbjct: 551 TDEWYDAHDMSIYRSALSCCVV 572

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>KLH17_RAT (Q8K430) Kelch-like protein 17 (Actinfilin)|
          Length = 640

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 36/108 (33%), Positives = 46/108 (42%)
 Frame = +2

Query: 287 SLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRK 466
           S  PV    S     G AVL G  LY+ GG D     +  V  Y+T+   W     M  +
Sbjct: 507 SWTPVASMLSRRSSAGVAVLEGA-LYVAGGNDGT-SCLNSVERYSTKAGAWESVAPMNIR 564

Query: 467 RHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMNT 610
           R       ++  LY  GG  +G   +L S E YNP  N+W   S M T
Sbjct: 565 RSTHDLVAMDGWLYAVGGN-DG-SSSLNSIEKYNPRTNKWVAASCMFT 610



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 35/116 (30%), Positives = 47/116 (40%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           +DP+   W S+  +            A L G  LY  GG D     +  V  Y  + N W
Sbjct: 454 YDPLTGTWTSIAAMSTRRRYV---RVATLDG-NLYAVGGYDS-SSHLATVEKYEPQVNSW 508

Query: 440 YRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMN 607
                ML +R   G  V+   LYVAGG  +G    L S E Y+     W  ++ MN
Sbjct: 509 TPVASMLSRRSSAGVAVLEGALYVAGGN-DGTS-CLNSVERYSTKAGAWESVAPMN 562



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 30/87 (34%), Positives = 40/87 (45%)
 Frame = +2

Query: 350 GCYLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECE 529
           G  LY  GG D     +  V  Y+  TN W     M  +R   G   ++  LY AGG  +
Sbjct: 386 GNRLYAVGGYDGT-SDLATVESYDPVTNTWQPEVSMGTRRSCLGVAALHGLLYAAGG-YD 443

Query: 530 GIQRTLRSAEVYNPNRNRWSCISEMNT 610
           G    L SAE Y+P    W+ I+ M+T
Sbjct: 444 GAS-CLNSAERYDPLTGTWTSIAAMST 469



 Score = 38.5 bits (88), Expect = 0.016
 Identities = 22/65 (33%), Positives = 31/65 (47%)
 Frame = +2

Query: 416 YNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCI 595
           Y+TRT++W+    M  +R   G   + N LY  GG  +G    L + E Y+P  N W   
Sbjct: 360 YDTRTDRWHVVASMSTRRARVGVAAVGNRLYAVGG-YDGTS-DLATVESYDPVTNTWQPE 417

Query: 596 SEMNT 610
             M T
Sbjct: 418 VSMGT 422



 Score = 33.9 bits (76), Expect = 0.38
 Identities = 18/46 (39%), Positives = 23/46 (50%)
 Frame = +2

Query: 356 YLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVI 493
           +LY  GG D    S+  +  YN RTNKW  A  M  +R   G  V+
Sbjct: 576 WLYAVGGNDG-SSSLNSIEKYNPRTNKWVAASCMFTRRSSVGVAVL 620

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>KLH17_MOUSE (Q6TDP3) Kelch-like protein 17 (Actinfilin)|
          Length = 640

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 36/108 (33%), Positives = 46/108 (42%)
 Frame = +2

Query: 287 SLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRK 466
           S  PV    S     G AVL G  LY+ GG D     +  V  Y+T+   W     M  +
Sbjct: 507 SWTPVASMLSRRSSAGVAVLEGA-LYVAGGNDGT-SCLNSVERYSTKAGAWESVAPMNIR 564

Query: 467 RHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMNT 610
           R       ++  LY  GG  +G   +L S E YNP  N+W   S M T
Sbjct: 565 RSTHDLVAMDGWLYAVGGN-DG-SSSLNSIEKYNPRTNKWVAASCMFT 610



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 35/116 (30%), Positives = 47/116 (40%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           +DP+   W S+  +            A L G  LY  GG D     +  V  Y  + N W
Sbjct: 454 YDPLTGTWTSIAAMSTRRRYV---RVATLDG-NLYAVGGYDS-SSHLATVEKYEPQVNSW 508

Query: 440 YRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMN 607
                ML +R   G  V+   LYVAGG  +G    L S E Y+     W  ++ MN
Sbjct: 509 TPVASMLSRRSSAGVAVLEGALYVAGGN-DGTS-CLNSVERYSTKAGAWESVAPMN 562



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 30/87 (34%), Positives = 40/87 (45%)
 Frame = +2

Query: 350 GCYLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECE 529
           G  LY  GG D     +  V  Y+  TN W     M  +R   G   ++  LY AGG  +
Sbjct: 386 GNRLYAVGGYDGT-SDLATVESYDPVTNTWQPEVSMGTRRSCLGVAALHGLLYAAGG-YD 443

Query: 530 GIQRTLRSAEVYNPNRNRWSCISEMNT 610
           G    L SAE Y+P    W+ I+ M+T
Sbjct: 444 GAS-CLNSAERYDPLTGTWTSIAAMST 469



 Score = 38.5 bits (88), Expect = 0.016
 Identities = 22/65 (33%), Positives = 31/65 (47%)
 Frame = +2

Query: 416 YNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCI 595
           Y+TRT++W+    M  +R   G   + N LY  GG  +G    L + E Y+P  N W   
Sbjct: 360 YDTRTDRWHVVASMSTRRARVGVAAVGNRLYAVGG-YDGTS-DLATVESYDPVTNTWQPE 417

Query: 596 SEMNT 610
             M T
Sbjct: 418 VSMGT 422



 Score = 33.9 bits (76), Expect = 0.38
 Identities = 18/46 (39%), Positives = 23/46 (50%)
 Frame = +2

Query: 356 YLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVI 493
           +LY  GG D    S+  +  YN RTNKW  A  M  +R   G  V+
Sbjct: 576 WLYAVGGNDG-SSSLNSIEKYNPRTNKWVAASCMFTRRSSVGVAVL 620

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>KLH17_HUMAN (Q6TDP4) Kelch-like protein 17 (Actinfilin)|
          Length = 642

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 36/116 (31%), Positives = 48/116 (41%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           +DP+   W S+  +            A L G  LY  GG D     +  V  Y  + N W
Sbjct: 456 YDPLTGTWTSVAAMSTRRRYV---RVATLDG-NLYAVGGYDS-SSHLATVEKYEPQVNVW 510

Query: 440 YRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMN 607
                ML +R   G  V+   LYVAGG  +G    L S E Y+P    W  ++ MN
Sbjct: 511 SPVASMLSRRSSAGVAVLEGALYVAGGN-DGTS-CLNSVERYSPKAGAWESVAPMN 564



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 36/117 (30%), Positives = 49/117 (41%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           ++P   +W    PV    S     G AVL G  LY+ GG D     +  V  Y+ +   W
Sbjct: 503 YEPQVNVWS---PVASMLSRRSSAGVAVLEGA-LYVAGGNDGT-SCLNSVERYSPKAGAW 557

Query: 440 YRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMNT 610
                M  +R       ++  LY  GG  +G   +L S E YNP  N+W   S M T
Sbjct: 558 ESVAPMNIRRSTHDLVAMDGWLYAVGGN-DG-SSSLNSIEKYNPRTNKWVAASCMFT 612



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 29/87 (33%), Positives = 40/87 (45%)
 Frame = +2

Query: 350 GCYLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECE 529
           G  LY  GG D     +  V  Y+  TN W     M  +R   G   ++  LY AGG  +
Sbjct: 388 GNRLYAVGGYDGT-SDLATVESYDPVTNTWQPEVSMGTRRSCLGVAALHGLLYSAGG-YD 445

Query: 530 GIQRTLRSAEVYNPNRNRWSCISEMNT 610
           G    L SAE Y+P    W+ ++ M+T
Sbjct: 446 GAS-CLNSAERYDPLTGTWTSVAAMST 471



 Score = 38.5 bits (88), Expect = 0.016
 Identities = 22/65 (33%), Positives = 31/65 (47%)
 Frame = +2

Query: 416 YNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCI 595
           Y+TRT++W+    M  +R   G   + N LY  GG  +G    L + E Y+P  N W   
Sbjct: 362 YDTRTDRWHVVASMSTRRARVGVAAVGNRLYAVGG-YDGTS-DLATVESYDPVTNTWQPE 419

Query: 596 SEMNT 610
             M T
Sbjct: 420 VSMGT 424



 Score = 34.3 bits (77), Expect = 0.29
 Identities = 24/78 (30%), Positives = 33/78 (42%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           + P    W S+ P+    S         + G +LY  GG D    S+  +  YN RTNKW
Sbjct: 550 YSPKAGAWESVAPMNIRRST---HDLVAMDG-WLYAVGGNDG-SSSLNSIEKYNPRTNKW 604

Query: 440 YRAPDMLRKRHLFGSCVI 493
             A  M  +R   G  V+
Sbjct: 605 VAASCMFTRRSSVGVAVL 622

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>KLH21_HUMAN (Q9UJP4) Kelch-like protein 21|
          Length = 539

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 40/146 (27%), Positives = 66/146 (45%), Gaps = 5/146 (3%)
 Frame = +2

Query: 182 RKKFGMAEEWVYV--FKRDRDQKLSWHAFDPVHQLWRSLPPVPPEYSEAVGFGCAVLS-G 352
           R   G+AE  V V    +D D+ ++   ++P    WR L     E+ + +G G ++++ G
Sbjct: 279 RPSTGLAEILVLVGGCDQDCDELVTVDCYNPQTGQWRYLA----EFPDHLGGGYSIVALG 334

Query: 353 CYLYLFGGKDPVRGSMRH--VVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGEC 526
             +Y+ GG D   GS  +  V  YN+  N+W     ML+ R    S V++  LYV   + 
Sbjct: 335 NDIYVTGGSD---GSRLYDCVWRYNSSVNEWAEVAPMLKAREYHSSSVLDGLLYVVAAD- 390

Query: 527 EGIQRTLRSAEVYNPNRNRWSCISEM 604
                   S E Y+   + W  +  M
Sbjct: 391 --------STERYDHTTDSWEALQPM 408

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>KLH10_HUMAN (Q6JEL2) Kelch-like protein 10|
          Length = 608

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 37/122 (30%), Positives = 55/122 (45%), Gaps = 5/122 (4%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDP-VRGSMRHVVFYNTRTNK 436
           FDPV + W  + P+   +S        VL G ++Y  GG D  VR  +     Y   TN+
Sbjct: 359 FDPVKKTWHQVAPM---HSRRCYVSVTVL-GNFIYAMGGFDGYVR--LNTAERYEPETNQ 412

Query: 437 WYRAPDMLRKRHLFGSCVINNCLYVAGG----ECEGIQRTLRSAEVYNPNRNRWSCISEM 604
           W     M  +R    +  +   +Y+ GG    EC      L +AEVYN   N+W+ I+ M
Sbjct: 413 WTLIAPMHEQRSDASATTLYGKVYICGGFNGNEC------LFTAEVYNTESNQWTVIAPM 466

Query: 605 NT 610
            +
Sbjct: 467 RS 468



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 35/115 (30%), Positives = 50/115 (43%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           ++P    W  + P+  + S+A       L G  +Y+ GG +         V YNT +N+W
Sbjct: 406 YEPETNQWTLIAPMHEQRSDA---SATTLYG-KVYICGGFNGNECLFTAEV-YNTESNQW 460

Query: 440 YRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEM 604
                M  +R   G       +Y  GG  +G  R LRSAE Y+P  N W  I  M
Sbjct: 461 TVIAPMRSRRSGIGVIAYGEHVYAVGG-FDGANR-LRSAEAYSPVANTWRTIPTM 513



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 29/103 (28%), Positives = 44/103 (42%)
 Frame = +2

Query: 299 VPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLF 478
           + P  S   G G  +  G ++Y  GG D     +R    Y+   N W   P M   R  F
Sbjct: 463 IAPMRSRRSGIG-VIAYGEHVYAVGGFDGAN-RLRSAEAYSPVANTWRTIPTMFNPRSNF 520

Query: 479 GSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMN 607
           G  V+++ L+V GG   G   T  + E Y+   + W    +M+
Sbjct: 521 GIEVVDDLLFVVGG-FNGFTTTF-NVECYDEKTDEWYDAHDMS 561



 Score = 37.7 bits (86), Expect = 0.027
 Identities = 24/82 (29%), Positives = 41/82 (50%)
 Frame = +2

Query: 248 SWHAFDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTR 427
           S  A+ PV   WR++P +   ++    FG  V+    L++ GG +    +  +V  Y+ +
Sbjct: 496 SAEAYSPVANTWRTIPTM---FNPRSNFGIEVVDDL-LFVVGGFNGFTTTF-NVECYDEK 550

Query: 428 TNKWYRAPDMLRKRHLFGSCVI 493
           T++WY A DM   R     CV+
Sbjct: 551 TDEWYDAHDMSIYRSALSCCVV 572

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>VMT9_MYXVL (P08073) Kelch repeat protein M-T9 (M9-R polypeptide)|
          Length = 509

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 26/87 (29%), Positives = 35/87 (40%)
 Frame = +2

Query: 281 WRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDML 460
           W S+ P+P   S A      V+    LY  GG+        HV  Y   +  W R  DM 
Sbjct: 395 WMSMEPLPEPRSGAT----TVVYNNRLYCIGGRIHGGAYTNHVYNYLDESRTWERVGDMA 450

Query: 461 RKRHLFGSCVINNCLYVAGGECEGIQR 541
             R     CV N  +YV GG    +++
Sbjct: 451 NVRRNPSCCVYNKAIYVLGGNTNAVEK 477



 Score = 38.1 bits (87), Expect = 0.020
 Identities = 19/60 (31%), Positives = 30/60 (50%)
 Frame = +2

Query: 407 VVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRW 586
           V+ Y+  TN++   P+M   R    +C++N  +YV GG  E   R + S E + P    W
Sbjct: 290 VLAYDLLTNEYSLMPEMGHYRRNASACIVNGYIYVVGGVDEE-NRLIGSVEYWQPGMEEW 348



 Score = 29.6 bits (65), Expect = 7.2
 Identities = 21/77 (27%), Positives = 32/77 (41%)
 Frame = +2

Query: 356 YLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGI 535
           Y+Y+ GG D     +  V ++     +W+ AP +         C  N  L++ GG  +  
Sbjct: 321 YIYVVGGVDEENRLIGSVEYWQPGMEEWHDAPYLQANVETATVCYRNE-LWIVGGTVDLY 379

Query: 536 QRTLRSAEVYNPNRNRW 586
             T  SA V     NRW
Sbjct: 380 HPTFISA-VKKLTDNRW 395

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>KBTB7_HUMAN (Q8WVZ9) Kelch repeat and BTB domain-containing protein 7|
          Length = 684

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 28/93 (30%), Positives = 45/93 (48%), Gaps = 2/93 (2%)
 Frame = +2

Query: 326 GFGCAVLSGCYLYLFGGKDPVRG-SMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNC 502
           G   A L+G Y+Y+ GG+DP+ G  ++ V  Y+ + N+W     +    + F   V+ N 
Sbjct: 427 GMDVAYLNG-YIYILGGRDPITGVKLKEVECYSVQRNQWALVAPVPHSFYSFELIVVQNY 485

Query: 503 LYVAGGECEGIQRTLRSAEVYNPNRNRW-SCIS 598
           LY         +R L     Y+P+ N W +C S
Sbjct: 486 LYAVNS-----KRML----CYDPSHNMWLNCAS 509



 Score = 34.3 bits (77), Expect = 0.29
 Identities = 16/61 (26%), Positives = 26/61 (42%)
 Frame = +2

Query: 416 YNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCI 595
           Y    N W +  D L  R       +N  +Y+ GG        L+  E Y+  RN+W+ +
Sbjct: 408 YKPAQNSWQQLADRLLCREGMDVAYLNGYIYILGGRDPITGVKLKEVECYSVQRNQWALV 467

Query: 596 S 598
           +
Sbjct: 468 A 468

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>KBTB6_HUMAN (Q86V97) Kelch repeat and BTB domain-containing protein 6|
          Length = 674

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 27/93 (29%), Positives = 42/93 (45%), Gaps = 2/93 (2%)
 Frame = +2

Query: 326 GFGCAVLSGCYLYLFGGKDPVRG-SMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNC 502
           G   A L+G Y+Y+ GG+DP+ G  ++ V  YN + N+W     +      F   VI + 
Sbjct: 427 GMDVAYLNG-YIYILGGRDPITGVKLKEVECYNVKRNQWALVAPLPHSFLSFDLMVIRDY 485

Query: 503 LYVAGGECEGIQRTLRSAEVYNPNRNRW-SCIS 598
           LY             +    Y+P+ N W  C+S
Sbjct: 486 LYALNS---------KRMFCYDPSHNMWLKCVS 509



 Score = 36.6 bits (83), Expect = 0.059
 Identities = 17/63 (26%), Positives = 27/63 (42%)
 Frame = +2

Query: 416 YNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCI 595
           Y    N W +  D L  R       +N  +Y+ GG        L+  E YN  RN+W+ +
Sbjct: 408 YKPAQNSWQQLADRLLCREGMDVAYLNGYIYILGGRDPITGVKLKEVECYNVKRNQWALV 467

Query: 596 SEM 604
           + +
Sbjct: 468 APL 470

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>KLH13_MOUSE (Q80TF4) Kelch-like protein 13 (BTB and kelch domain-containing|
           protein 2)
          Length = 604

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 30/120 (25%), Positives = 49/120 (40%), Gaps = 5/120 (4%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRH-----VVFYNT 424
           FDP    W    P+    +   G  C    G  LY+ GG    RG+  +       +Y+ 
Sbjct: 457 FDPDTDKWTQKAPM----TTVRGLHCMCTVGDRLYVIGGNH-FRGTSDYDDVLSCEYYSP 511

Query: 425 RTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEM 604
             ++W     MLR +   G  V  N +YV GG     +  +   + Y+P +N W  + ++
Sbjct: 512 ILDQWTPIASMLRGQSDVGVAVFENKIYVVGGYSWNNRCMVEIVQKYDPEKNEWHKVFDL 571



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 30/118 (25%), Positives = 53/118 (44%), Gaps = 1/118 (0%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           FDP +  W  +  +     +   F  + L G +LY  GG++   G +  V  YN RTN+W
Sbjct: 363 FDPRYNKWIQVASLN---EKRTFFHLSALKG-FLYAVGGRNAA-GELPTVECYNPRTNEW 417

Query: 440 YRAPDMLRKRHLFGSCVINNCLYVAGG-ECEGIQRTLRSAEVYNPNRNRWSCISEMNT 610
                M    +     V    +Y++GG   +  Q+ L     ++P+ ++W+  + M T
Sbjct: 418 TYVAKMNEPHYGHAGTVYGGVMYISGGITHDTFQKELM---CFDPDTDKWTQKAPMTT 472



 Score = 36.6 bits (83), Expect = 0.059
 Identities = 25/92 (27%), Positives = 41/92 (44%), Gaps = 9/92 (9%)
 Frame = +2

Query: 365 LFGGKDPVRGSMRHVVF------YNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGG-- 520
           ++GG   + G + H  F      ++  T+KW +   M   R L   C + + LYV GG  
Sbjct: 434 VYGGVMYISGGITHDTFQKELMCFDPDTDKWTQKAPMTTVRGLHCMCTVGDRLYVIGGNH 493

Query: 521 -ECEGIQRTLRSAEVYNPNRNRWSCISEMNTG 613
                    + S E Y+P  ++W+ I+ M  G
Sbjct: 494 FRGTSDYDDVLSCEYYSPILDQWTPIASMLRG 525



 Score = 36.2 bits (82), Expect = 0.077
 Identities = 18/67 (26%), Positives = 33/67 (49%), Gaps = 3/67 (4%)
 Frame = +2

Query: 416 YNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEV---YNPNRNRW 586
           Y+ +T++W     M   R+  G  VI N LYV GG+     +   + +    ++P  N+W
Sbjct: 311 YDEKTHEWKSLAPMDAPRYQHGIAVIGNFLYVVGGQSNYDTKGKTAVDTVFRFDPRYNKW 370

Query: 587 SCISEMN 607
             ++ +N
Sbjct: 371 IQVASLN 377

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>BKLH5_HUMAN (Q96NJ5) BTB and kelch domain-containing protein 5|
          Length = 620

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 26/83 (31%), Positives = 37/83 (44%)
 Frame = +2

Query: 356 YLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGI 535
           YLY  GG++ +R  +  V  Y  + NKW       R        V +  L+++GG     
Sbjct: 399 YLYAVGGRNELRQVLPTVERYCPKKNKWTFVQSFDRSLSCHAGYVADGLLWISGGVTNTA 458

Query: 536 QRTLRSAEVYNPNRNRWSCISEM 604
           Q   R   VY PN+N+W   S M
Sbjct: 459 QYQNR-LMVYEPNQNKWISRSPM 480



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 29/113 (25%), Positives = 50/113 (44%), Gaps = 4/113 (3%)
 Frame = +2

Query: 281 WRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGK-DPVRG---SMRHVVFYNTRTNKWYRA 448
           W  L  +P   S      C  + G +L++ GG+ +   G   ++R    Y+ R+N W   
Sbjct: 326 WSELASMPVGRSHH----CVAVMGDFLFVAGGEVEHASGRTCAVRTACRYDPRSNSWAEI 381

Query: 449 PDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMN 607
             M   R  F    +   LY  GG  E +++ L + E Y P +N+W+ +   +
Sbjct: 382 APMKNCREHFVLGAMEEYLYAVGGRNE-LRQVLPTVERYCPKKNKWTFVQSFD 433



 Score = 34.7 bits (78), Expect = 0.23
 Identities = 22/89 (24%), Positives = 38/89 (42%), Gaps = 4/89 (4%)
 Frame = +2

Query: 359 LYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGG---ECE 529
           L++ GG          ++ Y    NKW     ML++R       +   LYV GG   +  
Sbjct: 448 LWISGGVTNTAQYQNRLMVYEPNQNKWISRSPMLQRRVYHSMAAVQRKLYVLGGNDLDYN 507

Query: 530 GIQRTLRSAEVYNPNRNRWS-CISEMNTG 613
             +  +R  + YN + ++W+ C   + TG
Sbjct: 508 NDRILVRHIDSYNIDTDQWTRCNFNLLTG 536

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>KLHL6_MOUSE (Q6V595) Kelch-like protein 6|
          Length = 610

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 45/158 (28%), Positives = 65/158 (41%), Gaps = 13/158 (8%)
 Frame = +2

Query: 155 LSGNYYYSLRKKFGMAEEWVYVFK------RDRDQKLSWHAFDPVHQLWRSLPPVP---- 304
           LSGN   S R K  M E    VF       +D          DP+ +    +  +P    
Sbjct: 288 LSGNEIISERTKPRMHEFQSEVFMIIGGCTKDERFVAEVTCLDPLRRSRLEVAKLPLTEH 347

Query: 305 ---PEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHL 475
               E  + V F C  L    +Y+ GGK+    +   V  YN+  NKW +   +   R  
Sbjct: 348 ELESENKKWVEFACVTLKN-EVYISGGKE----TQHDVWKYNSSINKWIQIEYLNIGRWR 402

Query: 476 FGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWS 589
               V+   +YV GG  +G+QR + + E Y+P  N WS
Sbjct: 403 HKMVVLGGKVYVLGG-FDGLQR-INNVETYDPFHNCWS 438



 Score = 37.4 bits (85), Expect = 0.035
 Identities = 25/116 (21%), Positives = 45/116 (38%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           +DP H  W    P+    S       A      LY+ GG    + +     +Y+  TNKW
Sbjct: 430 YDPFHNCWSEAAPLHVHVSSFA----ATSHKKKLYVIGGGPNGKLATDKTQWYDPSTNKW 485

Query: 440 YRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMN 607
                M  +     +    + +YV GG        +R+   Y+P  + W  +++++
Sbjct: 486 VLKSAMPVEAKCINAVSFQDHIYVVGG-------AMRALYAYSPLEDSWCLVTQLS 534



 Score = 32.7 bits (73), Expect = 0.86
 Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 2/98 (2%)
 Frame = +2

Query: 242 KLSWHAFDPVHQLW--RSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVF 415
           K  W  +DP    W  +S  PV  +   AV F        ++Y+ GG      +MR +  
Sbjct: 474 KTQW--YDPSTNKWVLKSAMPVEAKCINAVSFQD------HIYVVGG------AMRALYA 519

Query: 416 YNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECE 529
           Y+   + W     +  +R   G    NN LY+ GG  E
Sbjct: 520 YSPLEDSWCLVTQLSHERASCGIAPCNNKLYITGGRDE 557

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>KLHL6_HUMAN (Q8WZ60) Kelch-like protein 6|
          Length = 610

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 45/158 (28%), Positives = 65/158 (41%), Gaps = 13/158 (8%)
 Frame = +2

Query: 155 LSGNYYYSLRKKFGMAEEWVYVFK------RDRDQKLSWHAFDPVHQLWRSLPPVP---- 304
           LSGN   S R K  M E    VF       +D          DP+ +    +  +P    
Sbjct: 288 LSGNEIISERTKPRMHEFQSEVFMIIGGCTKDERFVAEVTCLDPLRRSRLEVAKLPLTEH 347

Query: 305 ---PEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHL 475
               E  + V F C  L    +Y+ GGK+    +   V  YN+  NKW +   +   R  
Sbjct: 348 ELESENKKWVEFACVTLKN-EVYISGGKE----TQHDVWKYNSSINKWIQIEYLNIGRWR 402

Query: 476 FGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWS 589
               V+   +YV GG  +G+QR + + E Y+P  N WS
Sbjct: 403 HKMVVLGGKVYVIGG-FDGLQR-INNVETYDPFHNCWS 438



 Score = 30.0 bits (66), Expect = 5.6
 Identities = 24/92 (26%), Positives = 37/92 (40%), Gaps = 2/92 (2%)
 Frame = +2

Query: 260 FDPVHQLW--RSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTN 433
           +DP    W  ++  PV  +   AV F   +      Y+ GG      +MR +  Y+   +
Sbjct: 478 YDPSTNKWSLKAAMPVEAKCINAVSFRDRI------YVVGG------AMRALYAYSPLED 525

Query: 434 KWYRAPDMLRKRHLFGSCVINNCLYVAGGECE 529
            W     +  +R   G    NN LY+ GG  E
Sbjct: 526 SWCLVTQLSHERASCGIAPCNNRLYITGGRDE 557

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>KLH13_HUMAN (Q9P2N7) Kelch-like protein 13 (BTB and kelch domain-containing|
           protein 2)
          Length = 604

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 31/118 (26%), Positives = 52/118 (44%), Gaps = 1/118 (0%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           FDP +  W  +  +     +   F  + L G YLY  GG++   G +  V  YN RTN+W
Sbjct: 363 FDPRYNKWMQVASLN---EKRTFFHLSALKG-YLYAVGGRNAA-GELPTVECYNPRTNEW 417

Query: 440 YRAPDMLRKRHLFGSCVINNCLYVAGG-ECEGIQRTLRSAEVYNPNRNRWSCISEMNT 610
                M    +     V    +Y++GG   +  Q+ L     ++P+ ++W   + M T
Sbjct: 418 TYVAKMSEPHYGHAGTVYGGVMYISGGITHDTFQKELM---CFDPDTDKWIQKAPMTT 472



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 29/120 (24%), Positives = 50/120 (41%), Gaps = 5/120 (4%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRH-----VVFYNT 424
           FDP    W    P+    +   G  C    G  LY+ GG    RG+  +       +Y+ 
Sbjct: 457 FDPDTDKWIQKAPM----TTVRGLHCMCTVGERLYVIGGNH-FRGTSDYDDVLSCEYYSP 511

Query: 425 RTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEM 604
             ++W     MLR +   G  V  N +YV GG     +  +   + Y+P+++ W  + ++
Sbjct: 512 ILDQWTPIAAMLRGQSDVGVAVFENKIYVVGGYSWNNRCMVEIVQKYDPDKDEWHKVFDL 571



 Score = 36.2 bits (82), Expect = 0.077
 Identities = 25/92 (27%), Positives = 40/92 (43%), Gaps = 9/92 (9%)
 Frame = +2

Query: 365 LFGGKDPVRGSMRHVVF------YNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGG-- 520
           ++GG   + G + H  F      ++  T+KW +   M   R L   C +   LYV GG  
Sbjct: 434 VYGGVMYISGGITHDTFQKELMCFDPDTDKWIQKAPMTTVRGLHCMCTVGERLYVIGGNH 493

Query: 521 -ECEGIQRTLRSAEVYNPNRNRWSCISEMNTG 613
                    + S E Y+P  ++W+ I+ M  G
Sbjct: 494 FRGTSDYDDVLSCEYYSPILDQWTPIAAMLRG 525



 Score = 34.7 bits (78), Expect = 0.23
 Identities = 17/67 (25%), Positives = 32/67 (47%), Gaps = 3/67 (4%)
 Frame = +2

Query: 416 YNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEV---YNPNRNRW 586
           Y+ + ++W     M   R+  G  VI N LYV GG+     +   + +    ++P  N+W
Sbjct: 311 YDEKAHEWKSLAPMDAPRYQHGIAVIGNFLYVVGGQSNYDTKGKTAVDTVFRFDPRYNKW 370

Query: 587 SCISEMN 607
             ++ +N
Sbjct: 371 MQVASLN 377

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>KBTBA_HUMAN (O60662) Kelch repeat and BTB domain-containing protein 10|
           (Kelch-related protein 1) (Kel-like protein 23)
           (Sarcosin)
          Length = 606

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 38/149 (25%), Positives = 62/149 (41%), Gaps = 7/149 (4%)
 Frame = +2

Query: 176 SLRKKFGMAE--EWVYVFK-RDRDQKLSWHA---FDPVHQLWRSLPPVPPEYSEAVGFGC 337
           S R  FG+ E  + +YV   +D   + S  +   +DPV   W  +  +P +      +G 
Sbjct: 386 SARCLFGLGEVDDKIYVVAGKDLQTEASLDSVLCYDPVAAKWNEVKKLPIKV-----YGH 440

Query: 338 AVLSGC-YLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVA 514
            V+S    +Y  GGK   +     V  +N +   W     M   R +FG  V    + +A
Sbjct: 441 NVISHKGMIYCLGGKTDDKKCTNRVFIFNPKKGDWKDLAPMKIPRSMFGVAVHKGKIVIA 500

Query: 515 GGECEGIQRTLRSAEVYNPNRNRWSCISE 601
           GG  E       S E ++   N+W  ++E
Sbjct: 501 GGVTE--DGLSASVEAFDLTTNKWDVMTE 527



 Score = 29.6 bits (65), Expect = 7.2
 Identities = 14/58 (24%), Positives = 30/58 (51%)
 Frame = +2

Query: 431 NKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEM 604
           ++W   P +   R LFG   +++ +YV  G+    + +L S   Y+P   +W+ + ++
Sbjct: 376 SEWVGLPPLPSARCLFGLGEVDDKIYVVAGKDLQTEASLDSVLCYDPVAAKWNEVKKL 433

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>VC04_SWPVK (P32228) Protein C4|
          Length = 530

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 27/87 (31%), Positives = 41/87 (47%), Gaps = 4/87 (4%)
 Frame = +2

Query: 356 YLYLFGGK-DPVRGSMRH---VVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGE 523
           ++Y  GG+ D    S+ H   V  Y++R + W    +   KR    SCV NN LY+ GG 
Sbjct: 435 FIYCIGGRIDTPHISIEHTNDVYIYSSRDDCWKYLSNTNVKRSFCLSCVFNNELYIIGG- 493

Query: 524 CEGIQRTLRSAEVYNPNRNRWSCISEM 604
                    S E YN  +N W  ++++
Sbjct: 494 -----YNTNSVEKYNKLKNTWKRLNDI 515



 Score = 34.7 bits (78), Expect = 0.23
 Identities = 27/92 (29%), Positives = 37/92 (40%), Gaps = 6/92 (6%)
 Frame = +2

Query: 329 FGC-----AVLSGCYLYLFGGKDPVRGSM-RHVVFYNTRTNKWYRAPDMLRKRHLFGSCV 490
           FGC      V     LY+ GGK   RG   + V+ YN +   W   P++   R+    CV
Sbjct: 271 FGCKTHFSVVYLNSILYIIGGKK--RGYFTKEVLSYNIKNKLWCYEPELNYFRYDTSVCV 328

Query: 491 INNCLYVAGGECEGIQRTLRSAEVYNPNRNRW 586
            N  +Y  GG+      T    E + P    W
Sbjct: 329 SNGMIYSIGGKDTNGYMT-NIVEFWKPEWKSW 359

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>SCRA_LIMPO (Q25390) Alpha-scruin|
          Length = 918

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 36/123 (29%), Positives = 48/123 (39%), Gaps = 8/123 (6%)
 Frame = +2

Query: 260 FDPVHQLWR--SLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDP-VR--GSM---RHVVF 415
           + P+   W      P P  Y  A  +  A+      Y+ GG DP VR  G M   +    
Sbjct: 614 YHPLKDRWEFFGYMPQPRNYHAAAYYRSAI------YITGGYDPDVRTWGEMVATKTTFV 667

Query: 416 YNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCI 595
           Y   +  W R  DM   R      V N+ LY  GG  + I R + S E Y+   N W+  
Sbjct: 668 YELASKNWTRMGDMRCARSHHSLLVFNDVLYAIGGR-DDIGRLVSSVESYDHESNEWTME 726

Query: 596 SEM 604
             M
Sbjct: 727 KSM 729



 Score = 33.1 bits (74), Expect = 0.66
 Identities = 25/95 (26%), Positives = 41/95 (43%), Gaps = 8/95 (8%)
 Frame = +2

Query: 260  FDPVHQLWRSLPPVPPEYSEAVG--FGCAVLSGCYLYLFGGKDPVRGSMRHVV------F 415
            +DPV + W    P+       +G  FG A +    ++L GG  P      ++V       
Sbjct: 768  YDPVFKHWVDGRPL------RIGRAFGNAAVCDNKIWLCGGAAPSTDENNYLVSVPAIDV 821

Query: 416  YNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGG 520
            Y+  T +W +   +   RH      + +CLY+AGG
Sbjct: 822  YDEETMEWKQKTSLGCPRHSAIVVALESCLYIAGG 856

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>KLD8A_MOUSE (Q91XA8) Kelch domain-containing protein 8A|
          Length = 350

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 27/113 (23%), Positives = 52/113 (46%), Gaps = 4/113 (3%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           +D +  +W SL P+P     A  F    L G  +Y+ GG+   + ++     ++  +  W
Sbjct: 148 YDMLKDMWVSLAPMPTPRYAATSF----LRGSKIYVLGGRQS-KYAVNAFEVFDIESRSW 202

Query: 440 YRAPDMLRKRHLFGSCVINNCLYVAGGECEG----IQRTLRSAEVYNPNRNRW 586
            + P++  KR       ++N LY  GG  +G      + LR+ +V++  +  W
Sbjct: 203 TKFPNIPCKRAFSSFVTLDNHLYSLGGLRQGRLYRQPKFLRTMDVFDMEQGGW 255



 Score = 31.2 bits (69), Expect = 2.5
 Identities = 14/40 (35%), Positives = 18/40 (45%)
 Frame = +2

Query: 416 YNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGI 535
           ++   NKW   P M   R    S V  NCL   GG  +G+
Sbjct: 299 FHPEKNKWEALPPMPTPRCACSSIVFKNCLLAVGGVSQGL 338



 Score = 31.2 bits (69), Expect = 2.5
 Identities = 33/130 (25%), Positives = 56/130 (43%), Gaps = 9/130 (6%)
 Frame = +2

Query: 248 SWHAFDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVR-----GSMRHVV 412
           ++  FD   + W   P +P + +    F   V    +LY  GG    R       +R + 
Sbjct: 191 AFEVFDIESRSWTKFPNIPCKRA----FSSFVTLDNHLYSLGGLRQGRLYRQPKFLRTMD 246

Query: 413 FYNTRTNKWYRAPD--MLRKRHL-FGSCVINNCLYVAGGECEGIQRT-LRSAEVYNPNRN 580
            ++     W +      L+KR   F +  ++  + VAGG   G Q T L +AE ++P +N
Sbjct: 247 VFDMEQGGWLKMERSFFLKKRRADFVAGGLSGRVIVAGGL--GNQPTVLETAEAFHPEKN 304

Query: 581 RWSCISEMNT 610
           +W  +  M T
Sbjct: 305 KWEALPPMPT 314



 Score = 30.0 bits (66), Expect = 5.6
 Identities = 24/103 (23%), Positives = 41/103 (39%), Gaps = 1/103 (0%)
 Frame = +2

Query: 281 WRSLPPVPPEYSEAVGFGCAVL-SGCYLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDM 457
           W+ L P+P          C++L +G  +Y  GG D     M     Y+   ++W   P +
Sbjct: 11  WKRLAPLPSRRVY-----CSLLETGGQVYAIGGCDDNGVPMDCFEVYSPEADQWTSLPSL 65

Query: 458 LRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRW 586
              R       +   + V GG     Q  ++  E+YN +  +W
Sbjct: 66  PTARAGVAITALGKRIMVIGGVGTN-QLPVKVVEMYNIDEGKW 107

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>KHL15_BRARE (Q6DEL7) Kelch-like protein 15|
          Length = 604

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 45/161 (27%), Positives = 64/161 (39%), Gaps = 21/161 (13%)
 Frame = +2

Query: 194 GMAEEWVY-VFKRDRDQKL-SWHAFDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYL 367
           G+  +++Y V  R RD+   S   +D V   W  + P P       G    VL+G  LY+
Sbjct: 375 GVIGKYIYAVAGRTRDETFYSTERYDIVEDKWEFVDPYPVN---KYGHEGTVLNG-KLYI 430

Query: 368 FGGKDPVRGSMRHVVF---------YNTR-----TNKWYRAPDMLRKRHLFGSCVINNCL 505
            GG      S +  VF         + TR     TN W     M   R        N  L
Sbjct: 431 TGGITSSSTSKQVCVFDPGREGSSEHRTRRTPILTNCWENKSKMNYARCFHKMISHNGKL 490

Query: 506 YVAGGECEGIQRTLRS-----AEVYNPNRNRWSCISEMNTG 613
           YV GG C  ++ +  S      EVY+P  + W+ ++ M  G
Sbjct: 491 YVFGGVCVILRASFESQGCPSTEVYDPETDEWTILASMPIG 531

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>KLHL9_MOUSE (Q6ZPT1) Kelch-like protein 9|
          Length = 617

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 29/120 (24%), Positives = 49/120 (40%), Gaps = 5/120 (4%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRH-----VVFYNT 424
           FDP    W    P+    +   G  C    G  LY+ GG    RG+  +       +Y+ 
Sbjct: 466 FDPDTDKWTQKAPM----TTVRGLHCMCTVGDKLYVIGGNH-FRGTSDYDDVLSCEYYSP 520

Query: 425 RTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEM 604
             ++W     MLR +   G  V  N +YV GG     +  +   + Y+P ++ W  + ++
Sbjct: 521 TLDQWTPIAAMLRGQSDVGVAVFENKIYVVGGYSWNNRCMVEIVQKYDPEKDEWHKVFDL 580



 Score = 37.7 bits (86), Expect = 0.027
 Identities = 26/92 (28%), Positives = 40/92 (43%), Gaps = 9/92 (9%)
 Frame = +2

Query: 365 LFGGKDPVRGSMRHVVFYNTR------TNKWYRAPDMLRKRHLFGSCVINNCLYVAGGEC 526
           ++GG   + G + H  F N        T+KW +   M   R L   C + + LYV GG  
Sbjct: 443 VYGGLMYISGGITHDTFQNELMCFDPDTDKWTQKAPMTTVRGLHCMCTVGDKLYVIGGNH 502

Query: 527 ---EGIQRTLRSAEVYNPNRNRWSCISEMNTG 613
                    + S E Y+P  ++W+ I+ M  G
Sbjct: 503 FRGTSDYDDVLSCEYYSPTLDQWTPIAAMLRG 534



 Score = 37.4 bits (85), Expect = 0.035
 Identities = 29/118 (24%), Positives = 50/118 (42%), Gaps = 1/118 (0%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           FDP +  W  +  +     +   F  + L G +LY  GG+    G +  V  YN R N+W
Sbjct: 372 FDPRYNKWMQVASLN---EKRTFFHLSALKG-HLYAVGGRSAA-GELATVECYNPRMNEW 426

Query: 440 YRAPDMLRKRHLFGSCVINNCLYVAGG-ECEGIQRTLRSAEVYNPNRNRWSCISEMNT 610
                M    +     V    +Y++GG   +  Q  L     ++P+ ++W+  + M T
Sbjct: 427 SYVAKMSEPHYGHAGTVYGGLMYISGGITHDTFQNELM---CFDPDTDKWTQKAPMTT 481



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 18/67 (26%), Positives = 31/67 (46%), Gaps = 3/67 (4%)
 Frame = +2

Query: 416 YNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEV---YNPNRNRW 586
           Y+ R  +W     M   R+  G  VI N LYV GG+     +   + +    ++P  N+W
Sbjct: 320 YDERAQEWKSLAPMDAPRYQHGIAVIGNFLYVVGGQSNYDTKGKTAVDTVFRFDPRYNKW 379

Query: 587 SCISEMN 607
             ++ +N
Sbjct: 380 MQVASLN 386

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>KLHL9_HUMAN (Q9P2J3) Kelch-like protein 9|
          Length = 617

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 29/120 (24%), Positives = 49/120 (40%), Gaps = 5/120 (4%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRH-----VVFYNT 424
           FDP    W    P+    +   G  C    G  LY+ GG    RG+  +       +Y+ 
Sbjct: 466 FDPDTDKWMQKAPM----TTVRGLHCMCTVGDKLYVIGGNH-FRGTSDYDDVLSCEYYSP 520

Query: 425 RTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEM 604
             ++W     MLR +   G  V  N +YV GG     +  +   + Y+P ++ W  + ++
Sbjct: 521 TLDQWTPIAAMLRGQSDVGVAVFENKIYVVGGYSWNNRCMVEIVQKYDPEKDEWHKVFDL 580



 Score = 38.1 bits (87), Expect = 0.020
 Identities = 26/92 (28%), Positives = 40/92 (43%), Gaps = 9/92 (9%)
 Frame = +2

Query: 365 LFGGKDPVRGSMRHVVFYNTR------TNKWYRAPDMLRKRHLFGSCVINNCLYVAGGEC 526
           ++GG   + G + H  F N        T+KW +   M   R L   C + + LYV GG  
Sbjct: 443 VYGGLMYISGGITHDTFQNELMCFDPDTDKWMQKAPMTTVRGLHCMCTVGDKLYVIGGNH 502

Query: 527 ---EGIQRTLRSAEVYNPNRNRWSCISEMNTG 613
                    + S E Y+P  ++W+ I+ M  G
Sbjct: 503 FRGTSDYDDVLSCEYYSPTLDQWTPIAAMLRG 534



 Score = 36.6 bits (83), Expect = 0.059
 Identities = 29/118 (24%), Positives = 49/118 (41%), Gaps = 1/118 (0%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           FDP +  W  +  +     +   F  + L G +LY  GG+    G +  V  YN R N+W
Sbjct: 372 FDPRYNKWMQVASLN---EKRTFFHLSALKG-HLYAVGGRSAA-GELATVECYNPRMNEW 426

Query: 440 YRAPDMLRKRHLFGSCVINNCLYVAGG-ECEGIQRTLRSAEVYNPNRNRWSCISEMNT 610
                M    +     V    +Y++GG   +  Q  L     ++P+ ++W   + M T
Sbjct: 427 SYVAKMSEPHYGHAGTVYGGLMYISGGITHDTFQNELM---CFDPDTDKWMQKAPMTT 481



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 18/67 (26%), Positives = 31/67 (46%), Gaps = 3/67 (4%)
 Frame = +2

Query: 416 YNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEV---YNPNRNRW 586
           Y+ R  +W     M   R+  G  VI N LYV GG+     +   + +    ++P  N+W
Sbjct: 320 YDERAQEWRSLAPMDAPRYQHGIAVIGNFLYVVGGQSNYDTKGKTAVDTVFRFDPRYNKW 379

Query: 587 SCISEMN 607
             ++ +N
Sbjct: 380 MQVASLN 386

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>VMT8_MYXVL (P22611) Kelch repeat protein M-T8|
          Length = 515

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 1/84 (1%)
 Frame = +2

Query: 338 AVLSGCYLYLFGGK-DPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVA 514
           AV     LY  GGK D V    R V+ Y+ + N W R P++   R    +  I  C+Y+ 
Sbjct: 274 AVCMNDVLYFAGGKLDAV--PTRQVLSYDVKANTWSRQPNLSEFRSDAAAYAIGGCIYII 331

Query: 515 GGECEGIQRTLRSAEVYNPNRNRW 586
           GG  +   R   +   + P  +RW
Sbjct: 332 GG-YDANDRPTNTTLYWRPGYDRW 354



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 19/88 (21%), Positives = 37/88 (42%)
 Frame = +2

Query: 257 AFDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNK 436
           ++D     W   P +    S+A  +    + GC +Y+ GG D         +++    ++
Sbjct: 298 SYDVKANTWSRQPNLSEFRSDAAAYA---IGGC-IYIIGGYDANDRPTNTTLYWRPGYDR 353

Query: 437 WYRAPDMLRKRHLFGSCVINNCLYVAGG 520
           WYR P ++       +    N ++V GG
Sbjct: 354 WYRGPTLVEAVAETSAVCYKNEIWVLGG 381

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>KBTB9_MOUSE (Q80T74) Kelch repeat and BTB domain-containing protein 9|
          Length = 655

 Score = 39.3 bits (90), Expect = 0.009
 Identities = 26/79 (32%), Positives = 36/79 (45%)
 Frame = +2

Query: 359 LYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQ 538
           +Y  GG   V G++ HV  Y+T TN+W     + +  H   + V    +YV GG  E   
Sbjct: 465 IYTLGGLG-VAGNVDHVERYDTITNQWEAVAPLPKAVHSAAATVCGGKIYVFGGVNEA-G 522

Query: 539 RTLRSAEVYNPNRNRWSCI 595
           R     + Y P  N WS I
Sbjct: 523 RAAGVLQSYVPQTNTWSFI 541



 Score = 36.2 bits (82), Expect = 0.077
 Identities = 24/116 (20%), Positives = 47/116 (40%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           +D +   W ++ P+P    +AV    A + G  +Y+FGG +    +   +  Y  +TN W
Sbjct: 483 YDTITNQWEAVAPLP----KAVHSAAATVCGGKIYVFGGVNEAGRAAGVLQSYVPQTNTW 538

Query: 440 YRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMN 607
                 +       +  +N  +++ GG         R+  +Y+P +        MN
Sbjct: 539 SFIESPMIDNKYAPAVTLNGFVFILGG------AYARATTIYDPEKGNIKAGPNMN 588

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>KBTB9_HUMAN (Q96CT2) Kelch repeat and BTB domain-containing protein 9|
          Length = 655

 Score = 39.3 bits (90), Expect = 0.009
 Identities = 26/79 (32%), Positives = 36/79 (45%)
 Frame = +2

Query: 359 LYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQ 538
           +Y  GG   V G++ HV  Y+T TN+W     + +  H   + V    +YV GG  E   
Sbjct: 465 IYTLGGLG-VAGNVDHVERYDTITNQWEAVAPLPKAVHSAAATVCGGKIYVFGGVNEA-G 522

Query: 539 RTLRSAEVYNPNRNRWSCI 595
           R     + Y P  N WS I
Sbjct: 523 RAAGVLQSYVPQTNTWSFI 541



 Score = 36.2 bits (82), Expect = 0.077
 Identities = 24/116 (20%), Positives = 47/116 (40%)
 Frame = +2

Query: 260 FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW 439
           +D +   W ++ P+P    +AV    A + G  +Y+FGG +    +   +  Y  +TN W
Sbjct: 483 YDTITNQWEAVAPLP----KAVHSAAATVCGGKIYVFGGVNEAGRAAGVLQSYVPQTNTW 538

Query: 440 YRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMN 607
                 +       +  +N  +++ GG         R+  +Y+P +        MN
Sbjct: 539 SFIESPMIDNKYAPAVTLNGFVFILGG------AYARATTIYDPEKGNIKAGPNMN 588

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>VA55_VACCV (P24768) Kelch repeat protein A55|
          Length = 564

 Score = 39.3 bits (90), Expect = 0.009
 Identities = 26/93 (27%), Positives = 40/93 (43%), Gaps = 1/93 (1%)
 Frame = +2

Query: 329 FGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW-YRAPDMLRKRHLFGSCVINNCL 505
           F  AVL    +Y+ GG D        V+ YNT TN W Y  P++   R   G    +  +
Sbjct: 290 FAVAVLDNI-IYMMGGYDQSPYRSSKVIAYNTCTNSWIYDIPELKYPRSNCGGLADDEYI 348

Query: 506 YVAGGECEGIQRTLRSAEVYNPNRNRWSCISEM 604
           Y  GG  +       S + + P++  W   ++M
Sbjct: 349 YCIGGIRDQDSSLTSSIDKWKPSKPYWQKYAKM 381

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>VA55_VACCC (P21073) Kelch repeat protein A55|
          Length = 564

 Score = 39.3 bits (90), Expect = 0.009
 Identities = 26/93 (27%), Positives = 40/93 (43%), Gaps = 1/93 (1%)
 Frame = +2

Query: 329 FGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKW-YRAPDMLRKRHLFGSCVINNCL 505
           F  AVL    +Y+ GG D        V+ YNT TN W Y  P++   R   G    +  +
Sbjct: 290 FAVAVLDNI-IYMMGGYDQSPYRSSKVIAYNTCTNSWIYDIPELKYPRSNCGGLADDEYI 348

Query: 506 YVAGGECEGIQRTLRSAEVYNPNRNRWSCISEM 604
           Y  GG  +       S + + P++  W   ++M
Sbjct: 349 YCIGGIRDQDSSLTSSIDKWKPSKPYWQKYAKM 381

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>SCRB_LIMPO (Q25386) Beta-scruin|
          Length = 916

 Score = 38.9 bits (89), Expect = 0.012
 Identities = 28/83 (33%), Positives = 38/83 (45%), Gaps = 6/83 (7%)
 Frame = +2

Query: 359 LYLFGGKDP-VR--GSM---RHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGG 520
           +Y+ GG DP +R  G M   +    Y   +NKW R  DM   R      V N+ +YV GG
Sbjct: 639 IYVTGGCDPHIRCWGEMVATKMTFVYRLSSNKWTRVADMHSARSHHSMVVFNDSIYVIGG 698

Query: 521 ECEGIQRTLRSAEVYNPNRNRWS 589
             +   R   S E Y P  + W+
Sbjct: 699 R-DDSGRLSASVESYVPALDEWN 720



 Score = 37.4 bits (85), Expect = 0.035
 Identities = 29/121 (23%), Positives = 50/121 (41%), Gaps = 6/121 (4%)
 Frame = +2

Query: 260  FDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVV------FYN 421
            +DPV + W S  P+      A  FG AV+    ++L GG  P +    ++V       Y+
Sbjct: 766  YDPVFKHWVSGKPL----RIARAFGSAVVCDDKIWLCGGAAPSQDENNYLVSIPAIDVYD 821

Query: 422  TRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISE 601
                +W +   +   RH      + +CLY+ GG        +   E+Y  + +    I E
Sbjct: 822  NEALEWIQKATLSCPRHSSVVVALESCLYLIGGINSHELSAINRNELYTTDSDTVQSIRE 881

Query: 602  M 604
            +
Sbjct: 882  L 882



 Score = 37.4 bits (85), Expect = 0.035
 Identities = 25/88 (28%), Positives = 45/88 (51%), Gaps = 6/88 (6%)
 Frame = +2

Query: 359 LYLFGGKDP---VRGSMR--HVVFYNTRTNK-WYRAPDMLRKRHLFGSCVINNCLYVAGG 520
           +YLFGG +P   ++G M+     F  T   K W R  DM   R   G  +++  ++V GG
Sbjct: 135 VYLFGGYNPLHCIKGKMQATSTTFQLTLDVKQWRRRADMPSARAHHGVTIMDERIFVFGG 194

Query: 521 ECEGIQRTLRSAEVYNPNRNRWSCISEM 604
           + +     + S E+Y P  ++W+ ++ +
Sbjct: 195 K-DSNGNIIASVEMYEPELDQWTSLASI 221



 Score = 33.9 bits (76), Expect = 0.38
 Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 7/83 (8%)
 Frame = +2

Query: 359 LYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINN--CLYVAGG---E 523
           +++FGGKD     +  V  Y    ++W     +     L GS V NN   +YV GG   +
Sbjct: 189 IFVFGGKDSNGNIIASVEMYEPELDQWTSLASI--PEPLMGSAVTNNEGLIYVVGGLTTK 246

Query: 524 CEGIQRTLRSAEVY--NPNRNRW 586
            E  Q  + S ++Y  +P  N+W
Sbjct: 247 KEKNQEGVLSNKIYCFDPLNNKW 269



 Score = 30.0 bits (66), Expect = 5.6
 Identities = 20/84 (23%), Positives = 37/84 (44%), Gaps = 6/84 (7%)
 Frame = +2

Query: 377 KDPVRGSMRHVVF-YNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGG-----ECEGIQ 538
           +DP+  S    VF Y+   ++W     M   R+   +      +YV GG      C G  
Sbjct: 596 QDPMNVSYGRSVFQYHPLKDRWEFFGFMSLPRNHHAAAYYRGAIYVTGGCDPHIRCWGEM 655

Query: 539 RTLRSAEVYNPNRNRWSCISEMNT 610
              +   VY  + N+W+ +++M++
Sbjct: 656 VATKMTFVYRLSSNKWTRVADMHS 679

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>VC13_SWPVK (P32206) Protein C13|
          Length = 500

 Score = 37.7 bits (86), Expect = 0.027
 Identities = 23/83 (27%), Positives = 37/83 (44%)
 Frame = +2

Query: 338 AVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAG 517
           +VL    LYL GG +     +  +   +TR+      P +L  R   G  +  N +YV G
Sbjct: 295 SVLMNDILYLIGGINKSLDPVSDITSVDTRSFIELHTPPLLHPRKCPGVAIFKNRIYVVG 354

Query: 518 GECEGIQRTLRSAEVYNPNRNRW 586
           G   G    L++ E ++P   +W
Sbjct: 355 G--IGYDGPLKTVESWSPGEQQW 375



 Score = 33.9 bits (76), Expect = 0.38
 Identities = 25/85 (29%), Positives = 41/85 (48%), Gaps = 2/85 (2%)
 Frame = +2

Query: 359 LYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVI--NNCLYVAGGECEG 532
           +Y+ GG     G ++ V  ++    +W     +L+ R  F  C+I  +N LYV GG    
Sbjct: 350 IYVVGGIG-YDGPLKTVESWSPGEQQWREEVPLLQPR--FNPCIIGTDNDLYVVGG---- 402

Query: 533 IQRTLRSAEVYNPNRNRWSCISEMN 607
           I    ++ E+Y+   N WS  + MN
Sbjct: 403 ISEDDKTIEIYSYEENTWSIGNAMN 427



 Score = 30.8 bits (68), Expect = 3.3
 Identities = 28/116 (24%), Positives = 51/116 (43%), Gaps = 5/116 (4%)
 Frame = +2

Query: 257 AFDPVHQLWRS-LPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTN 433
           ++ P  Q WR  +P + P ++      C + +   LY+ GG   +    + +  Y+   N
Sbjct: 367 SWSPGEQQWREEVPLLQPRFNP-----CIIGTDNDLYVVGG---ISEDDKTIEIYSYEEN 418

Query: 434 KWYRAPDMLRKRHLFGSCVI--NNCLYVAGGEC--EGIQRTLRSAEVYNPNRNRWS 589
            W    + +   H FG C+   +  +Y+ GG    + I       E YNP+ N+W+
Sbjct: 419 TW-SIGNAMNYSH-FGGCIAYHHGYIYMIGGLSFIDNIH-VFTMVEKYNPHSNKWT 471

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>KHL15_HUMAN (Q96M94) Kelch-like protein 15|
          Length = 604

 Score = 37.0 bits (84), Expect = 0.045
 Identities = 41/161 (25%), Positives = 63/161 (39%), Gaps = 21/161 (13%)
 Frame = +2

Query: 194 GMAEEWVY-VFKRDRDQKL-SWHAFDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYL 367
           G+  +++Y V  R RD+   S   +D  +  W  + P P       G    VL+   L++
Sbjct: 375 GVIGKFIYAVAGRTRDETFYSTERYDITNDKWEFVDPYPVN---KYGHEGTVLNN-KLFI 430

Query: 368 FGGKDPVRGSMRHVVFYNTR--------------TNKWYRAPDMLRKRHLFGSCVINNCL 505
            GG      S +  VF  ++              TN W     M   R        N  L
Sbjct: 431 TGGITSSSTSKQVCVFDPSKEGTIEQRTRRTQVVTNCWENKSKMNYARCFHKMISYNGKL 490

Query: 506 YVAGGECEGIQRTLRS-----AEVYNPNRNRWSCISEMNTG 613
           YV GG C  ++ +  S      EVYNP  ++W+ ++ M  G
Sbjct: 491 YVFGGVCVILRASFESQGCPSTEVYNPETDQWTILASMPIG 531

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>KLDC3_RAT (Q6AYI2) Kelch domain-containing protein 3|
          Length = 382

 Score = 37.0 bits (84), Expect = 0.045
 Identities = 25/104 (24%), Positives = 47/104 (45%), Gaps = 10/104 (9%)
 Frame = +2

Query: 239 QKLSWHAFDPVHQLWRSLPPVPPEYSEA------VGFG-CAVLSGCYLYLFGGKDPVRGS 397
           +++  H F+ V   W  LPPV P           + +G   VL    ++L+GG++   G+
Sbjct: 42  RQIDVHIFNAVSLRWTKLPPVRPAVRGQAPVVPYMRYGHSTVLIDDTVFLWGGRNDTEGA 101

Query: 398 MRHVVFYNTRTNKWYR---APDMLRKRHLFGSCVINNCLYVAGG 520
              +  ++  T+KW     +  +   R    +CV+   +Y+ GG
Sbjct: 102 CNVLYAFDVNTHKWSTPRVSGTVPGARDGHSACVLGKIMYIFGG 145



 Score = 33.1 bits (74), Expect = 0.66
 Identities = 27/109 (24%), Positives = 39/109 (35%), Gaps = 14/109 (12%)
 Frame = +2

Query: 329 FGCAVLSGCYLYLFGGKDPVRGSMR--------HVVFYNTRTNKWYRAP------DMLRK 466
           F  A + G ++Y+FGG+    G            +  ++TRT  W   P      +  R 
Sbjct: 182 FHSATMLGNHMYVFGGRADRFGPFHSNNEIYCNRIRVFDTRTEAWLDCPHTPVLPEGRRS 241

Query: 467 RHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMNTG 613
              FG    N  LY+ GG    + R       +NP    W  I     G
Sbjct: 242 HSAFG---YNGELYIFGGYNARLNRHFHDLWKFNPGSFTWKKIEPKGKG 287

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>KLDC3_MOUSE (Q8VEM9) Kelch domain-containing protein 3 (Protein Peas) (Testis|
           intracellular mediator protein)
          Length = 382

 Score = 37.0 bits (84), Expect = 0.045
 Identities = 25/104 (24%), Positives = 47/104 (45%), Gaps = 10/104 (9%)
 Frame = +2

Query: 239 QKLSWHAFDPVHQLWRSLPPVPPEYSEA------VGFG-CAVLSGCYLYLFGGKDPVRGS 397
           +++  H F+ V   W  LPPV P           + +G   VL    ++L+GG++   G+
Sbjct: 42  RQIDVHIFNAVSLRWTKLPPVRPAVRGQAPVVPYMRYGHSTVLIDDTVFLWGGRNDTEGA 101

Query: 398 MRHVVFYNTRTNKWYR---APDMLRKRHLFGSCVINNCLYVAGG 520
              +  ++  T+KW     +  +   R    +CV+   +Y+ GG
Sbjct: 102 CNVLYAFDVNTHKWSTPRVSGTVPGARDGHSACVLGKIMYIFGG 145



 Score = 33.1 bits (74), Expect = 0.66
 Identities = 27/109 (24%), Positives = 39/109 (35%), Gaps = 14/109 (12%)
 Frame = +2

Query: 329 FGCAVLSGCYLYLFGGKDPVRGSMR--------HVVFYNTRTNKWYRAP------DMLRK 466
           F  A + G ++Y+FGG+    G            +  ++TRT  W   P      +  R 
Sbjct: 182 FHSATMLGNHMYVFGGRADRFGPFHSNNEIYCNRIRVFDTRTEAWLDCPHTPVLPEGRRS 241

Query: 467 RHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMNTG 613
              FG    N  LY+ GG    + R       +NP    W  I     G
Sbjct: 242 HSAFG---YNGELYIFGGYNARLNRHFHDLWKFNPGSFTWKKIEPKGKG 287

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>VC02_VACCV (P17371) Kelch repeat protein C2|
          Length = 512

 Score = 35.0 bits (79), Expect = 0.17
 Identities = 16/53 (30%), Positives = 29/53 (54%)
 Frame = +2

Query: 428 TNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRW 586
           T+KW R P+++  R+   S  +N+ +YV GG     ++ +   +V    +NRW
Sbjct: 331 TSKWIRLPNLITPRYSGASVFVNDDIYVMGGVYTTYEKYVVLNDVECFTKNRW 383



 Score = 30.0 bits (66), Expect = 5.6
 Identities = 16/68 (23%), Positives = 31/68 (45%)
 Frame = +2

Query: 407 VVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRW 586
           +  Y+ RT  W    +    R  + + V++NCLY+ GG      R + S    +    +W
Sbjct: 232 ITHYSPRTEYWTIVGNT--DRQFYNANVLHNCLYIIGGMIN--NRHVYSVSRVDLETKKW 287

Query: 587 SCISEMNT 610
             ++ M++
Sbjct: 288 KTVTNMSS 295

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>VC02_VACCT (Q9JFG1) Kelch repeat protein C2|
          Length = 512

 Score = 35.0 bits (79), Expect = 0.17
 Identities = 16/53 (30%), Positives = 29/53 (54%)
 Frame = +2

Query: 428 TNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRW 586
           T+KW R P+++  R+   S  +N+ +YV GG     ++ +   +V    +NRW
Sbjct: 331 TSKWIRLPNLITPRYSGASVFVNDDIYVMGGVYTTYEKYVVLNDVECFTKNRW 383



 Score = 30.0 bits (66), Expect = 5.6
 Identities = 16/68 (23%), Positives = 31/68 (45%)
 Frame = +2

Query: 407 VVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRW 586
           +  Y+ RT  W    +    R  + + V++NCLY+ GG      R + S    +    +W
Sbjct: 232 ITHYSPRTEYWTIVGNT--DRQFYNANVLHNCLYIIGGMIN--NRHVYSVSRVDLETKKW 287

Query: 587 SCISEMNT 610
             ++ M++
Sbjct: 288 KTVTNMSS 295



 Score = 29.3 bits (64), Expect = 9.5
 Identities = 21/64 (32%), Positives = 28/64 (43%)
 Frame = +2

Query: 329 FGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLY 508
           +   VL  C LY+ GG    R  +  V   +  T KW    +M   +    +CV N  LY
Sbjct: 253 YNANVLHNC-LYIIGGMINNR-HVYSVSRVDLETKKWKTVTNMSSLKSEVSTCVNNGKLY 310

Query: 509 VAGG 520
           V GG
Sbjct: 311 VIGG 314

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>VC02_VACCC (P21037) Kelch repeat protein C2|
          Length = 512

 Score = 35.0 bits (79), Expect = 0.17
 Identities = 16/53 (30%), Positives = 29/53 (54%)
 Frame = +2

Query: 428 TNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRW 586
           T+KW R P+++  R+   S  +N+ +YV GG     ++ +   +V    +NRW
Sbjct: 331 TSKWIRLPNLITPRYSGASVFVNDDIYVMGGVYTTYEKYVVLNDVECFTKNRW 383



 Score = 30.0 bits (66), Expect = 5.6
 Identities = 16/68 (23%), Positives = 31/68 (45%)
 Frame = +2

Query: 407 VVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRW 586
           +  Y+ RT  W    +    R  + + V++NCLY+ GG      R + S    +    +W
Sbjct: 232 ITHYSPRTEYWTIVGNT--DRQFYNANVLHNCLYIIGGMIN--NRHVYSVSRVDLETKKW 287

Query: 587 SCISEMNT 610
             ++ M++
Sbjct: 288 KTVTNMSS 295

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>VC02_RABPU (Q6RZS3) Kelch repeat protein C2|
          Length = 512

 Score = 35.0 bits (79), Expect = 0.17
 Identities = 16/53 (30%), Positives = 29/53 (54%)
 Frame = +2

Query: 428 TNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRW 586
           T+KW R P+++  R+   S  +N+ +YV GG     ++ +   +V    +NRW
Sbjct: 331 TSKWIRLPNLITPRYSGASVFVNDDIYVMGGVYTTYEKYVVLNDVECFTKNRW 383



 Score = 30.0 bits (66), Expect = 5.6
 Identities = 16/68 (23%), Positives = 31/68 (45%)
 Frame = +2

Query: 407 VVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRW 586
           +  Y+ RT  W    +    R  + + V++NCLY+ GG      R + S    +    +W
Sbjct: 232 ITHYSPRTEYWTIVGNT--DRQFYNANVLHNCLYIIGGMIN--NRHVYSVSRVDLETKKW 287

Query: 587 SCISEMNT 610
             ++ M++
Sbjct: 288 KTVTNMSS 295



 Score = 29.3 bits (64), Expect = 9.5
 Identities = 21/64 (32%), Positives = 28/64 (43%)
 Frame = +2

Query: 329 FGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLY 508
           +   VL  C LY+ GG    R  +  V   +  T KW    +M   +    +CV N  LY
Sbjct: 253 YNANVLHNC-LYIIGGMINNR-HVYSVSRVDLETKKWKTVTNMSSLKSEVSTCVNNGKLY 310

Query: 509 VAGG 520
           V GG
Sbjct: 311 VIGG 314

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>VC02_CWPXG (P87617) Kelch repeat protein C2|
          Length = 512

 Score = 35.0 bits (79), Expect = 0.17
 Identities = 16/53 (30%), Positives = 29/53 (54%)
 Frame = +2

Query: 428 TNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRW 586
           T+KW R P+++  R+   S  +N+ +YV GG     ++ +   +V    +NRW
Sbjct: 331 TSKWIRLPNLITPRYSGASVFVNDDIYVMGGVYTTYEKYVVLNDVECFTKNRW 383



 Score = 30.0 bits (66), Expect = 5.6
 Identities = 16/68 (23%), Positives = 31/68 (45%)
 Frame = +2

Query: 407 VVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRW 586
           +  Y+ RT  W    +    R  + + V++NCLY+ GG      R + S    +    +W
Sbjct: 232 ITHYSPRTEYWTIVGNT--DRQFYNANVLHNCLYIIGGMIN--NRHVYSVSRVDLKTKKW 287

Query: 587 SCISEMNT 610
             ++ M++
Sbjct: 288 KTVTNMSS 295

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>VC02_CAMPS (Q776A6) Kelch repeat protein C2|
          Length = 512

 Score = 35.0 bits (79), Expect = 0.17
 Identities = 16/53 (30%), Positives = 29/53 (54%)
 Frame = +2

Query: 428 TNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRW 586
           T+KW R P+++  R+   S  +N+ +YV GG     ++ +   +V    +NRW
Sbjct: 331 TSKWIRLPNLITPRYSGASVFVNDDIYVMGGVYTTYEKYVVLNDVECFTKNRW 383

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>VC02_CAMPM (Q8V2Z3) Kelch repeat protein C2|
          Length = 512

 Score = 35.0 bits (79), Expect = 0.17
 Identities = 16/53 (30%), Positives = 29/53 (54%)
 Frame = +2

Query: 428 TNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRW 586
           T+KW R P+++  R+   S  +N+ +YV GG     ++ +   +V    +NRW
Sbjct: 331 TSKWIRLPNLITPRYSGASVFVNDDIYVMGGVYTTYEKYVVLNDVECFTKNRW 383

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>KLDC3_HUMAN (Q9BQ90) Kelch domain-containing protein 3 (Protein Peas) (Testis|
           intracellular mediator protein)
          Length = 382

 Score = 35.0 bits (79), Expect = 0.17
 Identities = 24/105 (22%), Positives = 45/105 (42%), Gaps = 11/105 (10%)
 Frame = +2

Query: 239 QKLSWHAFDPVHQLWRSLPPV--------PPEYSEAVGFGCAVLSGCYLYLFGGKDPVRG 394
           +++  H F+ V   W  LPPV        P       G    ++    L L+GG++   G
Sbjct: 42  RQIDVHIFNAVSLRWTKLPPVKSAIRGQAPVVPYMRYGHSTVLIDDTVL-LWGGRNDTEG 100

Query: 395 SMRHVVFYNTRTNKWYR---APDMLRKRHLFGSCVINNCLYVAGG 520
           +   +  ++  T+KW+    +  +   R    +CV+   +Y+ GG
Sbjct: 101 ACNVLYAFDVNTHKWFTPRVSGTVPGARDGHSACVLGKIMYIFGG 145



 Score = 32.7 bits (73), Expect = 0.86
 Identities = 27/109 (24%), Positives = 39/109 (35%), Gaps = 14/109 (12%)
 Frame = +2

Query: 329 FGCAVLSGCYLYLFGGKDPVRGSM--------RHVVFYNTRTNKWYRA------PDMLRK 466
           F  A + G ++Y+FGG+    G            +  ++TRT  W         P+  R 
Sbjct: 182 FHSATMLGSHMYVFGGRADRFGPFHSNNEIYCNRIRVFDTRTEAWLDCPPTPVLPEGRRS 241

Query: 467 RHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSCISEMNTG 613
              FG    N  LY+ GG    + R       +NP    W  I     G
Sbjct: 242 HSAFG---YNGELYIFGGYNARLNRHFHDLWKFNPVSFTWKKIEPKGKG 287

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>SPE26_CAEEL (Q10579) Spermatocyte protein spe-26|
          Length = 570

 Score = 34.7 bits (78), Expect = 0.23
 Identities = 27/84 (32%), Positives = 39/84 (46%), Gaps = 7/84 (8%)
 Frame = +2

Query: 359 LYLFGGKD-------PVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAG 517
           +Y+FGG++        VR     V  ++ +TNKW     +   R    + V  N +YV+G
Sbjct: 342 IYVFGGQNFREITRTAVRSRTGEV--FDPKTNKWTETASLSDMRSDCAAEVFENQIYVSG 399

Query: 518 GECEGIQRTLRSAEVYNPNRNRWS 589
           G        L S EVYNP  N +S
Sbjct: 400 G--FNGDMILASVEVYNPIGNVFS 421

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>KBTB3_MOUSE (Q8BHI4) Kelch repeat and BTB domain-containing protein 3 (BTB and|
           kelch domain-containing protein 3)
          Length = 607

 Score = 33.9 bits (76), Expect = 0.38
 Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 2/68 (2%)
 Frame = +2

Query: 416 YNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQ--RTLRSAEVYNPNRNRWS 589
           Y    N+++    M   R +  S +  N L+V GG+  G Q  ++L   E YNP    W+
Sbjct: 372 YCPAKNEFFCVSAMKTPRTMHTSVMALNRLFVIGGKTRGSQDIKSLLDVESYNPLSREWT 431

Query: 590 CISEMNTG 613
            +S +  G
Sbjct: 432 SVSPLPRG 439

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>VC02_ECTVM (Q8JLI4) Kelch repeat protein C2|
          Length = 512

 Score = 33.5 bits (75), Expect = 0.50
 Identities = 20/76 (26%), Positives = 36/76 (47%)
 Frame = +2

Query: 359 LYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQ 538
           LY+ GG +    S     +     +KW R P+++  R+   S  +N+ +YV GG     +
Sbjct: 309 LYVIGGLE-FSISTAVAEYLKHGASKWIRLPNLITPRYSGASVFVNDDIYVMGGVYTTYE 367

Query: 539 RTLRSAEVYNPNRNRW 586
           + +   +V    +NRW
Sbjct: 368 KYVVLNDVECFTKNRW 383



 Score = 30.0 bits (66), Expect = 5.6
 Identities = 21/64 (32%), Positives = 29/64 (45%)
 Frame = +2

Query: 329 FGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLY 508
           +   VL  C LY+ GG    R  +  V   + +T KW    +M   +    +CV N  LY
Sbjct: 253 YNANVLHNC-LYIIGGMINNR-HVYSVSRVDLKTKKWKTVTNMSSLKSEVSTCVNNGKLY 310

Query: 509 VAGG 520
           V GG
Sbjct: 311 VIGG 314



 Score = 30.0 bits (66), Expect = 5.6
 Identities = 16/68 (23%), Positives = 31/68 (45%)
 Frame = +2

Query: 407 VVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRW 586
           +  Y+ RT  W    +    R  + + V++NCLY+ GG      R + S    +    +W
Sbjct: 232 ITHYSPRTEYWTIVGNT--DRQFYNANVLHNCLYIIGGMIN--NRHVYSVSRVDLKTKKW 287

Query: 587 SCISEMNT 610
             ++ M++
Sbjct: 288 KTVTNMSS 295

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>KEL10_CAEEL (P34569) Kelch repeat-containing protein kel-10|
          Length = 566

 Score = 32.7 bits (73), Expect = 0.86
 Identities = 24/86 (27%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
 Frame = +2

Query: 359 LYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNC----LYVAGGEC 526
           L ++GG +  +   +  V ++  T +W    +M  KR    S  IN+     L  A G  
Sbjct: 305 LIVYGGFNGTQ-QFQTTVLFDLSTKEWRSGANMNDKRCYVTSARINDSHGRPLIFACGGM 363

Query: 527 EGIQRTLRSAEVYNPNRNRWSCISEM 604
            G+ R L++AE+Y+   ++WS ++ M
Sbjct: 364 NGVSR-LKTAEMYDYRADQWSEVANM 388

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>VF03_VACCV (P24357) Kelch repeat protein F3|
          Length = 480

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 27/97 (27%), Positives = 40/97 (41%)
 Frame = +2

Query: 296 PVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHL 475
           P+PP  S  + +   + +   LY+ GG        R   F+      W   P +L+ R  
Sbjct: 301 PIPPMNSPRL-YASGIPANNKLYVVGGLPNPTSVERW--FHGDAA--WVNMPSLLKPRCN 355

Query: 476 FGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRW 586
                INN +YV GG  E    T  + E   PN ++W
Sbjct: 356 PAVASINNVIYVMGGHSE----TDTTTEYLLPNHDQW 388

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>VF03_VACCC (P21013) Kelch repeat protein F3|
          Length = 480

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 27/97 (27%), Positives = 40/97 (41%)
 Frame = +2

Query: 296 PVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHL 475
           P+PP  S  + +   + +   LY+ GG        R   F+      W   P +L+ R  
Sbjct: 301 PIPPMNSPRL-YATGIPANNKLYVVGGLPNPTSVERW--FHGDAA--WVNMPSLLKPRCN 355

Query: 476 FGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRW 586
                INN +YV GG  E    T  + E   PN ++W
Sbjct: 356 PAVASINNVIYVMGGHSE----TDTTTEYLLPNHDQW 388

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>VF03_VACCA (O57174) Kelch repeat protein F3|
          Length = 476

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 27/97 (27%), Positives = 40/97 (41%)
 Frame = +2

Query: 296 PVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHL 475
           P+PP  S  + +   + +   LY+ GG        R   F+      W   P +L+ R  
Sbjct: 297 PIPPMNSPRL-YASGIPANNKLYVVGGLPNPTSVERW--FHGDAA--WVNMPSLLKPRCN 351

Query: 476 FGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRW 586
                INN +YV GG  E    T  + E   PN ++W
Sbjct: 352 PAVASINNVIYVMGGHSE----TDTTTEYLLPNHDQW 384

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>KLD8A_HUMAN (Q8IYD2) Kelch domain-containing protein 8A|
          Length = 350

 Score = 32.0 bits (71), Expect = 1.5
 Identities = 35/130 (26%), Positives = 56/130 (43%), Gaps = 9/130 (6%)
 Frame = +2

Query: 248 SWHAFDPVHQLWRSLPPVPPEYSEAVGFGCAVLSGCYLYLFGGKDPVR-----GSMRHVV 412
           ++  FD   + W   P +P  Y  A  F   V    +LY  GG    R       +R + 
Sbjct: 191 AFEVFDIETRSWTKFPNIP--YKRA--FSSFVTLDNHLYSLGGLRQGRLYRQPKFLRTMD 246

Query: 413 FYNTRTNKWYRAPD--MLRKRHL-FGSCVINNCLYVAGGECEGIQRT-LRSAEVYNPNRN 580
            ++     W +      L+KR   F +  ++  + VAGG   G Q T L +AE ++P +N
Sbjct: 247 VFDMEQGGWLKMERSFFLKKRRADFVAGSLSGRVIVAGGL--GNQPTVLETAEAFHPGKN 304

Query: 581 RWSCISEMNT 610
           +W  +  M T
Sbjct: 305 KWEILPAMPT 314



 Score = 29.6 bits (65), Expect = 7.2
 Identities = 14/35 (40%), Positives = 17/35 (48%)
 Frame = +2

Query: 431 NKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGI 535
           NKW   P M   R    S V+ NCL   GG  +G+
Sbjct: 304 NKWEILPAMPTPRCACSSIVVKNCLLAVGGVNQGL 338

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>KEL2_YEAST (P50090) Kelch repeat-containing protein 2|
          Length = 882

 Score = 31.6 bits (70), Expect = 1.9
 Identities = 21/86 (24%), Positives = 33/86 (38%), Gaps = 3/86 (3%)
 Frame = +2

Query: 209 WVYVFKRDRDQKLSWHAFDPVHQLWRSLPPV---PPEYSEAVGFGCAVLSGCYLYLFGGK 379
           WV+  +  +      + +DP    W  +      PP   E      +V+    + + GGK
Sbjct: 270 WVFGGETPKTISNDTYRYDPAQSEWSKVKTTGEKPPPIQEHA----SVVYKHLMCVLGGK 325

Query: 380 DPVRGSMRHVVFYNTRTNKWYRAPDM 457
           D        V F N  + KWY+ P M
Sbjct: 326 DTHNAYSNDVYFLNLLSLKWYKLPRM 351

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>Y939_SULTO (Q973G3) Hypothetical protein ST0939 precursor|
          Length = 709

 Score = 31.6 bits (70), Expect = 1.9
 Identities = 17/54 (31%), Positives = 24/54 (44%)
 Frame = +2

Query: 359 LYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGG 520
           ++L GG++     +  V  Y      WY  P +       G+ V NN LYV GG
Sbjct: 50  IFLIGGENLYSTPVNSVYVYEN--GSWYLGPSLPFSLSSAGATVCNNTLYVVGG 101

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>XERC_SHEON (Q7ZAJ5) Tyrosine recombinase xerC|
          Length = 299

 Score = 31.6 bits (70), Expect = 1.9
 Identities = 15/33 (45%), Positives = 21/33 (63%), Gaps = 1/33 (3%)
 Frame = +1

Query: 409 RVLQYSDKQ-VVPGSRYATEAALIWLLCHKQLP 504
           RVL   +K+ +VP  RYA +A   WL C +Q+P
Sbjct: 167 RVLGKGNKERIVPVGRYAIDAISAWLECRRQIP 199

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>VB10_VACCV (Q76ZL3) Kelch repeat protein B10|
          Length = 166

 Score = 31.2 bits (69), Expect = 2.5
 Identities = 13/32 (40%), Positives = 17/32 (53%)
 Frame = +2

Query: 416 YNTRTNKWYRAPDMLRKRHLFGSCVINNCLYV 511
           YN RTNKW+     + K  +   C +NN  YV
Sbjct: 102 YNPRTNKWFDISYTIYKISISSLCKLNNVFYV 133

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>VB10_VACCT (Q77TF6) Kelch repeat protein B10|
          Length = 166

 Score = 31.2 bits (69), Expect = 2.5
 Identities = 13/32 (40%), Positives = 17/32 (53%)
 Frame = +2

Query: 416 YNTRTNKWYRAPDMLRKRHLFGSCVINNCLYV 511
           YN RTNKW+     + K  +   C +NN  YV
Sbjct: 102 YNPRTNKWFDISYTIYKISISSLCKLNNVFYV 133

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>VB10_VACCC (P68687) Kelch repeat protein B10|
          Length = 166

 Score = 31.2 bits (69), Expect = 2.5
 Identities = 13/32 (40%), Positives = 17/32 (53%)
 Frame = +2

Query: 416 YNTRTNKWYRAPDMLRKRHLFGSCVINNCLYV 511
           YN RTNKW+     + K  +   C +NN  YV
Sbjct: 102 YNPRTNKWFDISYTIYKISISSLCKLNNVFYV 133

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>VB10_RABPU (Q6RZB9) Kelch repeat protein B10|
          Length = 166

 Score = 31.2 bits (69), Expect = 2.5
 Identities = 13/32 (40%), Positives = 17/32 (53%)
 Frame = +2

Query: 416 YNTRTNKWYRAPDMLRKRHLFGSCVINNCLYV 511
           YN RTNKW+     + K  +   C +NN  YV
Sbjct: 102 YNPRTNKWFDISYTIYKISISSLCKLNNVFYV 133

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>KLD8B_RAT (Q5XIA9) Kelch domain-containing protein 8B|
          Length = 354

 Score = 31.2 bits (69), Expect = 2.5
 Identities = 15/54 (27%), Positives = 24/54 (44%)
 Frame = +2

Query: 359 LYLFGGKDPVRGSMRHVVFYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGG 520
           +Y  GG  P       V+ Y +R ++W   P M    +   + +  N +YV GG
Sbjct: 129 VYALGGMGPDTAPQAQVLVYESRRDRWLSLPSMPTPCYGASTFLHGNKIYVLGG 182

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>VB10_VACCA (O57257) Kelch repeat protein B10|
          Length = 158

 Score = 31.2 bits (69), Expect = 2.5
 Identities = 13/32 (40%), Positives = 17/32 (53%)
 Frame = +2

Query: 416 YNTRTNKWYRAPDMLRKRHLFGSCVINNCLYV 511
           YN RTNKW+     + K  +   C +NN  YV
Sbjct: 102 YNPRTNKWFDISYTIYKISISSLCKLNNVFYV 133

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>YT73_CAEEL (Q11087) Hypothetical protein C01C10.3|
          Length = 391

 Score = 30.8 bits (68), Expect = 3.3
 Identities = 21/69 (30%), Positives = 33/69 (47%)
 Frame = +3

Query: 51  FCLAFLMTWLFHV*CGFLEPSTLIFVWSVENGADFYLGITITRCGRNLAWQKNGFTSSKG 230
           F L    T LF+    +LE      V +  N    ++G T+T  G NLA    G+   K 
Sbjct: 67  FPLMLFSTPLFN----YLEHKLCAMVNAHWNAVSVFVGATVTEYGTNLA----GYAEEKC 118

Query: 231 IVIRNYLGM 257
           +++ N+LG+
Sbjct: 119 LLLANHLGL 127

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>NDUB4_MOUSE (Q9CQC7) NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit|
           4 (EC 1.6.5.3) (EC 1.6.99.3) (NADH-ubiquinone
           oxidoreductase B15 subunit) (Complex I-B15) (CI-B15)
          Length = 128

 Score = 30.8 bits (68), Expect = 3.3
 Identities = 22/61 (36%), Positives = 26/61 (42%), Gaps = 11/61 (18%)
 Frame = +2

Query: 95  RVSRAEHPNLRLVCRKWSRLLSGNYYYSLRKK-----------FGMAEEWVYVFKRDRDQ 241
           RVS  E P L     +W+   S N Y + R             FG    W YVFK DRD+
Sbjct: 55  RVSHIEDPALI----RWTYARSANIYPNFRPTPKNSLLGAVAGFGPLIFWYYVFKTDRDR 110

Query: 242 K 244
           K
Sbjct: 111 K 111

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>KBTB2_HUMAN (Q8IY47) Kelch repeat and BTB domain-containing protein 2 (BTB and|
           kelch domain-containing protein 1)
          Length = 623

 Score = 30.8 bits (68), Expect = 3.3
 Identities = 14/64 (21%), Positives = 29/64 (45%)
 Frame = +2

Query: 413 FYNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLRSAEVYNPNRNRWSC 592
           +++ + N W+    ML  R           +Y  GG+  G +   R+ E Y+  ++ W+ 
Sbjct: 352 WFDAQQNTWFPKTPMLFVRIKPSLVCCEGYIYAIGGDSVGGELNRRTVERYDTEKDEWTM 411

Query: 593 ISEM 604
           +S +
Sbjct: 412 VSPL 415

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>LCMT2_HUMAN (O60294) Leucine carboxyl methyltransferase 2 (EC 2.1.1.-)|
           (p21WAF1/CIP1 promoter-interacting protein)
          Length = 686

 Score = 30.4 bits (67), Expect = 4.2
 Identities = 16/58 (27%), Positives = 26/58 (44%), Gaps = 3/58 (5%)
 Frame = +2

Query: 356 YLYLFGGKDPVRGSMRHVVFYNTRTNKWYRAP---DMLRKRHLFGSCVINNCLYVAGG 520
           YL+++GG+  V   +    F +  T  W R P   ++   RH   +C       +AGG
Sbjct: 494 YLFVYGGRSVVEPVLSDWHFLHVGTMAWVRIPVEGEVPEARHSHSACTWQGGALIAGG 551

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>CALI_HUMAN (Q13939) Calicin|
          Length = 588

 Score = 30.4 bits (67), Expect = 4.2
 Identities = 20/81 (24%), Positives = 35/81 (43%), Gaps = 1/81 (1%)
 Frame = +2

Query: 374 GKDPVRGSMRHVVF-YNTRTNKWYRAPDMLRKRHLFGSCVINNCLYVAGGECEGIQRTLR 550
           G     G     VF Y  + N W +  DM  +     +      +Y++GG  E I   L+
Sbjct: 285 GGQKAHGQFNDGVFAYIIQENLWMKLSDMPYRAAALSATSAGRYIYISGGTTEQIS-GLK 343

Query: 551 SAEVYNPNRNRWSCISEMNTG 613
           +A  Y+ + N W+ + ++  G
Sbjct: 344 TAWRYDMDDNSWTKLPDLPIG 364

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>CD34_MOUSE (Q64314) Hematopoietic progenitor cell antigen CD34 precursor|
          Length = 382

 Score = 30.0 bits (66), Expect = 5.6
 Identities = 17/42 (40%), Positives = 26/42 (61%), Gaps = 1/42 (2%)
 Frame = -3

Query: 392 LVLGLCLQISTNSSH*E-QRNQSPQLLNTLVEREEATSRAGA 270
           L  G+CL++S  SS  E ++ +   L+  L E+EEA + AGA
Sbjct: 182 LAQGICLELSEASSCEEFKKEKGEDLIQILCEKEEAEADAGA 223

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>TEA3_SCHPO (O14248) Tip elongation aberrant protein 3 (Cell polarity protein|
           tea3)
          Length = 1125

 Score = 29.6 bits (65), Expect = 7.2
 Identities = 21/72 (29%), Positives = 33/72 (45%), Gaps = 8/72 (11%)
 Frame = +2

Query: 341 VLSGCYLYLFGGKDPVRGSMRHV-----VFYNTRTNKWYRAPD---MLRKRHLFGSCVIN 496
           V S   +YLFGG D    S   V       YN ++N+W        +   R      +++
Sbjct: 119 VCSADTIYLFGGCDSETDSTFEVGDNSLYAYNFKSNQWNLVSTQSPLPSPRTGHSMLLVD 178

Query: 497 NCLYVAGGECEG 532
           + L++ GGEC+G
Sbjct: 179 SKLWIFGGECQG 190


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 95,958,030
Number of Sequences: 219361
Number of extensions: 2216071
Number of successful extensions: 6341
Number of sequences better than 10.0: 106
Number of HSP's better than 10.0 without gapping: 5728
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6192
length of database: 80,573,946
effective HSP length: 107
effective length of database: 57,102,319
effective search space used: 5481822624
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

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full-length cDNA and EST

Clone Information

BLAST Search Result