ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | baal19m17 |
|---|---|
| Clone Library Name | barley_pub |
>ASPRX_ORYSA (P42211) Aspartic proteinase precursor (EC 3.4.23.-)| Length = 496 Score = 280 bits (717), Expect = 2e-75 Identities = 141/178 (79%), Positives = 156/178 (87%) Frame = +3 Query: 54 MGQRLLLLVTTCLWAISCAVPHHASSRDGLLRINLNKRSLTHESLAAAKAARQYGALRLK 233 M +R LLLVTTCLWA+SCA+ HASS DG LR+NLNK+ L E L AAK A+Q L LK Sbjct: 1 MAKRHLLLVTTCLWALSCALLLHASS-DGFLRVNLNKKRLDKEDLTAAKLAQQGNRL-LK 58 Query: 234 SGNSDSDIVPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHP 413 +G+SDSD VPLVDYLNTQYYGVIGLG+PPQNFTVIFDTGSSNLWVPS+KCYFSIACYLH Sbjct: 59 TGSSDSDPVPLVDYLNTQYYGVIGLGSPPQNFTVIFDTGSSNLWVPSAKCYFSIACYLHS 118 Query: 414 KYRSSRSTTYKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEATRETSVSF 587 +Y S +S++YKADGE CKITYGSGAISGFFS DNVLVGDLVVKNQKFIEATRETSV+F Sbjct: 119 RYNSKKSSSYKADGETCKITYGSGAISGFFSKDNVLVGDLVVKNQKFIEATRETSVTF 176
>ASPR1_ORYSA (Q42456) Aspartic proteinase oryzasin-1 precursor (EC 3.4.23.-)| Length = 509 Score = 189 bits (479), Expect = 7e-48 Identities = 96/186 (51%), Positives = 129/186 (69%), Gaps = 8/186 (4%) Frame = +3 Query: 54 MGQRLLLLVTTCLWAISCAVPHHASSRDGLLRINLNKRSLTHESLAAAKAARQYGALRLK 233 MG R + LV + +P AS+ +GL+RI L KR + S AA+ + + GA RL Sbjct: 1 MGTRSVALVLLAAVLLQALLP--ASAAEGLVRIALKKRPIDENSRVAARLSGEEGARRLG 58 Query: 234 --------SGNSDSDIVPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYF 389 G + DIV L +Y+N QY+G IG+GTPPQ FTVIFDTGSSNLWVPS+KCYF Sbjct: 59 LRGANSLGGGGGEGDIVALKNYMNAQYFGEIGVGTPPQKFTVIFDTGSSNLWVPSAKCYF 118 Query: 390 SIACYLHPKYRSSRSTTYKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEATR 569 SIAC+ H +Y+S +S+TY+ +G+ I YG+G+I+GFFS D+V VGDLVVK+Q+FIEAT+ Sbjct: 119 SIACFFHSRYKSGQSSTYQKNGKPAAIQYGTGSIAGFFSEDSVTVGDLVVKDQEFIEATK 178 Query: 570 ETSVSF 587 E ++F Sbjct: 179 EPGLTF 184
>ASPR_HORVU (P42210) Phytepsin precursor (EC 3.4.23.40) (Aspartic proteinase)| [Contains: Phytepsin 32 kDa subunit; Phytepsin 29 kDa subunit; Phytepsin 16 kDa subunit; Phytepsin 11 kDa subunit] Length = 508 Score = 180 bits (456), Expect = 3e-45 Identities = 97/186 (52%), Positives = 126/186 (67%), Gaps = 6/186 (3%) Frame = +3 Query: 48 GTMGQRLLLLVTTCLWAISCAVPHHASSRDGLLRINLNKRSLTHESLAAA------KAAR 209 GT G L LL L + +P AS +GL+RI L KR + S A + Sbjct: 2 GTRGLALALLAAVLL--LQTVLPA-ASEAEGLVRIALKKRPIDRNSRVATGLSGGEEQPL 58 Query: 210 QYGALRLKSGNSDSDIVPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYF 389 GA L+S + DIV L +Y+N QY+G IG+GTPPQ FTVIFDTGSSNLWVPS+KCYF Sbjct: 59 LSGANPLRS-EEEGDIVALKNYMNAQYFGEIGVGTPPQKFTVIFDTGSSNLWVPSAKCYF 117 Query: 390 SIACYLHPKYRSSRSTTYKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEATR 569 SIACYLH +Y++ S+TYK +G+ I YG+G+I+G+FS D+V VGDLVVK+Q+FIEAT+ Sbjct: 118 SIACYLHSRYKAGASSTYKKNGKPAAIQYGTGSIAGYFSEDSVTVGDLVVKDQEFIEATK 177 Query: 570 ETSVSF 587 E ++F Sbjct: 178 EPGITF 183
>CYPR1_CYNCA (P40782) Cyprosin precursor (EC 3.4.23.-) (Fragment)| Length = 473 Score = 173 bits (438), Expect = 4e-43 Identities = 82/147 (55%), Positives = 109/147 (74%) Frame = +3 Query: 147 RINLNKRSLTHESLAAAKAARQYGALRLKSGNSDSDIVPLVDYLNTQYYGVIGLGTPPQN 326 ++N+ H A A R+YG +R +SD +++ L +Y++ QY+G IG+GTPPQ Sbjct: 5 KVNILNHPGEHAGSNDANARRKYG-VRGNFRDSDGELIALKNYMDAQYFGEIGIGTPPQK 63 Query: 327 FTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSSRSTTYKADGENCKITYGSGAISGFFS 506 FTVIFDTGSSNLWVPSSKCYFS+AC H KYRS+ STTYK +G++ I YG+G+ISGFFS Sbjct: 64 FTVIFDTGSSNLWVPSSKCYFSVACLFHSKYRSTDSTTYKKNGKSAAIQYGTGSISGFFS 123 Query: 507 NDNVLVGDLVVKNQKFIEATRETSVSF 587 D+V +GDL+VK Q FIEAT+E ++F Sbjct: 124 QDSVKLGDLLVKEQDFIEATKEPGITF 150
>ASPR_CUCPE (O04057) Aspartic proteinase precursor (EC 3.4.23.-)| Length = 513 Score = 172 bits (435), Expect = 8e-43 Identities = 91/166 (54%), Positives = 115/166 (69%), Gaps = 11/166 (6%) Frame = +3 Query: 123 ASSRDGLLRINLNKRSLTHESLAAAK-----------AARQYGALRLKSGNSDSDIVPLV 269 ++S DGLLR+ L K L E+ AA+ A R+Y +SD+DIV L Sbjct: 24 SASNDGLLRVGLKKIKLDPENRLAARVESKDAEILKAAFRKYNPKGNLGESSDTDIVALK 83 Query: 270 DYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSSRSTTYKA 449 +YL+ QYYG I +GTPPQ FTVIFDTGSSNLWV +C FS+AC+ H +Y+SSRS++YK Sbjct: 84 NYLDAQYYGEIAIGTPPQKFTVIFDTGSSNLWV-LCECLFSVACHFHARYKSSRSSSYKK 142 Query: 450 DGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEATRETSVSF 587 +G + I YG+GA+SGFFS DNV VGDLVVK Q FIEATRE S++F Sbjct: 143 NGTSASIRYGTGAVSGFFSYDNVKVGDLVVKEQVFIEATREPSLTF 188
>CARP_NEUCR (Q01294) Vacuolar protease A precursor (EC 3.4.23.-)| Length = 396 Score = 135 bits (341), Expect = 7e-32 Identities = 62/110 (56%), Positives = 82/110 (74%) Frame = +3 Query: 258 VPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSSRST 437 VP+ +++N QY+ I +GTPPQ F V+ DTGSSNLWVPSS+C SIACYLH KY SS S+ Sbjct: 75 VPITNFMNAQYFSEITIGTPPQTFKVVLDTGSSNLWVPSSQCG-SIACYLHNKYESSESS 133 Query: 438 TYKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEATRETSVSF 587 TYK +G + KI YGSG++SGF S D + +GD+ + +Q F EAT E ++F Sbjct: 134 TYKKNGTSFKIEYGSGSLSGFVSQDRMTIGDITINDQLFAEATSEPGLAF 183
>CATD_CHICK (Q05744) Cathepsin D precursor (EC 3.4.23.5) [Contains: Cathepsin D| light chain; Cathepsin D heavy chain] Length = 398 Score = 130 bits (328), Expect = 2e-30 Identities = 74/160 (46%), Positives = 101/160 (63%), Gaps = 11/160 (6%) Frame = +3 Query: 141 LLRINLNKRSLTHESLAAA-------KAARQYGALRLKSGNSD-SDIVP--LVDYLNTQY 290 L+RI L K + T L A Q+ L+ K G +D ++ P L +Y++ QY Sbjct: 21 LIRIPLTKFTSTRRMLTEVGSEIPDMNAITQF--LKFKLGFADLAEPTPEILKNYMDAQY 78 Query: 291 YGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCY-FSIACYLHPKYRSSRSTTYKADGENCK 467 YG IG+GTPPQ FTV+FDTGSSNLWVPS C+ IAC LH KY +S+S+TY +G Sbjct: 79 YGEIGIGTPPQKFTVVFDTGSSNLWVPSVHCHLLDIACLLHHKYDASKSSTYVENGTEFA 138 Query: 468 ITYGSGAISGFFSNDNVLVGDLVVKNQKFIEATRETSVSF 587 I YG+G++SGF S D V +G+L +KNQ F EA ++ ++F Sbjct: 139 IHYGTGSLSGFLSQDTVTLGNLKIKNQIFGEAVKQPGITF 178
>NAPSA_MOUSE (O09043) Napsin-A precursor (EC 3.4.23.-) (Kidney-derived aspartic| protease-like protein) (KDAP-1) (KAP) Length = 419 Score = 129 bits (325), Expect = 5e-30 Identities = 72/175 (41%), Positives = 101/175 (57%), Gaps = 2/175 (1%) Frame = +3 Query: 69 LLLVTTCLWAISCAVPHHASSRDGLLRINLNKRSLTHESLAAAKAARQYGAL-RLKSGNS 245 LLL+ CL + P A L+R+ L + L H L Q L R + Sbjct: 4 LLLLLLCL-LLGNLEPEEAK----LIRVPLQRIHLGHRILNPLNGWEQLAELSRTSTSGG 58 Query: 246 DSDIVPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHPKYR 422 + VPL ++NTQY+G IGLGTPPQNFTV+FDTGSSNLWVPS++C +FS+AC+ H ++ Sbjct: 59 NPSFVPLSKFMNTQYFGTIGLGTPPQNFTVVFDTGSSNLWVPSTRCHFFSLACWFHHRFN 118 Query: 423 SSRSTTYKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEATRETSVSF 587 S++++ +G I YG+G +SG S DN+ +G + F EA E S+ F Sbjct: 119 PKASSSFRPNGTKFAIQYGTGRLSGILSQDNLTIGGIHDAFVTFGEALWEPSLIF 173
>CARP_YEAST (P07267) Saccharopepsin precursor (EC 3.4.23.25) (Aspartate| protease) (Proteinase A) (Proteinase YSCA) Length = 405 Score = 129 bits (324), Expect = 6e-30 Identities = 61/110 (55%), Positives = 78/110 (70%) Frame = +3 Query: 258 VPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSSRST 437 VPL +YLN QYY I LGTPPQNF VI DTGSSNLWVPS++C S+AC+LH KY S+ Sbjct: 81 VPLTNYLNAQYYTDITLGTPPQNFKVILDTGSSNLWVPSNEC-GSLACFLHSKYDHEASS 139 Query: 438 TYKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEATRETSVSF 587 +YKA+G I YG+G++ G+ S D + +GDL + Q F EAT E ++F Sbjct: 140 SYKANGTEFAIQYGTGSLEGYISQDTLSIGDLTIPKQDFAEATSEPGLTF 189
>CATD_CLUHA (Q9DEX3) Cathepsin D precursor (EC 3.4.23.5)| Length = 396 Score = 127 bits (319), Expect = 2e-29 Identities = 71/164 (43%), Positives = 100/164 (60%), Gaps = 9/164 (5%) Frame = +3 Query: 123 ASSRDGLLRINLNK-----RSLTHESLAAAKAARQYGALRLKSGNSDSDIVP---LVDYL 278 A + D ++RI L K R+L+ L + +L+ G S+ L +Y+ Sbjct: 13 AWTSDAIVRIPLKKFRSIRRTLSDSGLNVEQLLAGTNSLQHNQGFPSSNAPTPETLKNYM 72 Query: 279 NTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFS-IACYLHPKYRSSRSTTYKADG 455 + QYYG IGLGTP Q FTV+FDTGSSNLW+PS C F+ IAC LH KY ++S+TY +G Sbjct: 73 DAQYYGEIGLGTPVQMFTVVFDTGSSNLWLPSIHCSFTDIACLLHHKYNGAKSSTYVKNG 132 Query: 456 ENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEATRETSVSF 587 I YGSG++SG+ S D+ +GD+VV+ Q F EA ++ V+F Sbjct: 133 TEFAIQYGSGSLSGYLSQDSCTIGDIVVEKQLFGEAIKQPGVAF 176
>CARPV_CANAL (P10977) Vacuolar aspartic protease precursor (EC 3.4.23.-)| (Aspartate protease) (ACP) Length = 419 Score = 121 bits (304), Expect = 1e-27 Identities = 61/119 (51%), Positives = 77/119 (64%) Frame = +3 Query: 231 KSGNSDSDIVPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLH 410 K G D+ PL +YLN QY+ I +GTP Q F VI DTGSSNLWVPS C S+AC+LH Sbjct: 88 KGGKYDA---PLTNYLNAQYFTEIQIGTPGQPFKVILDTGSSNLWVPSQDCT-SLACFLH 143 Query: 411 PKYRSSRSTTYKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEATRETSVSF 587 KY S+TYK +G I YGSG++ G+ S D + +GDLV+ Q F EAT E ++F Sbjct: 144 AKYDHDASSTYKVNGSEFSIQYGSGSMEGYISQDVLTIGDLVIPGQDFAEATSEPGLAF 202
>ASPP_AEDAE (Q03168) Lysosomal aspartic protease precursor (EC 3.4.23.-)| Length = 387 Score = 121 bits (303), Expect = 2e-27 Identities = 57/110 (51%), Positives = 77/110 (70%), Gaps = 1/110 (0%) Frame = +3 Query: 261 PLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYF-SIACYLHPKYRSSRST 437 PL +YL+ QYYG I +GTPPQ+F V+FDTGSSNLWVPS +C F +IAC +H KY + +S+ Sbjct: 59 PLSNYLDAQYYGAITIGTPPQSFKVVFDTGSSNLWVPSKECSFTNIACLMHNKYNAKKSS 118 Query: 438 TYKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEATRETSVSF 587 T++ +G I YGSG++SG+ S D V +G + V Q F EA E + F Sbjct: 119 TFEKNGTAFHIQYGSGSLSGYLSTDTVGLGGVSVTKQTFAEAINEPGLVF 168
>RENI_CANFA (Q6DYE7) Renin precursor (EC 3.4.23.15) (Angiotensinogenase)| Length = 403 Score = 119 bits (299), Expect = 5e-27 Identities = 64/122 (52%), Positives = 79/122 (64%), Gaps = 1/122 (0%) Frame = +3 Query: 225 RLKSGNSDSDIVPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCY-FSIAC 401 RL SGNS S +V L +YL+TQYYG IG+GTPPQ F V+FDTGS+NLWVPS++C AC Sbjct: 65 RLSSGNSTSPVV-LTNYLDTQYYGEIGIGTPPQTFKVVFDTGSANLWVPSTRCSPLYTAC 123 Query: 402 YLHPKYRSSRSTTYKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEATRETSV 581 +H Y SS S++Y +G I YGSG + GF S D V VG + V Q F E T + Sbjct: 124 EIHCLYDSSESSSYMENGTTFTIRYGSGKVKGFLSQDMVTVGGITV-TQTFGEVTELPLI 182 Query: 582 SF 587 F Sbjct: 183 PF 184
>CATD_RAT (P24268) Cathepsin D precursor (EC 3.4.23.5) [Contains: Cathepsin D| 12 kDa light chain; Cathepsin D 9 kDa light chain; Cathepsin D 34 kDa heavy chain; Cathepsin D 30 kDa heavy chain] Length = 407 Score = 118 bits (296), Expect = 1e-26 Identities = 61/115 (53%), Positives = 78/115 (67%), Gaps = 7/115 (6%) Frame = +3 Query: 264 LVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHPKYRSSRSTT 440 L +YL+ QYYG IG+GTPPQ FTV+FDTGSSNLWVPS C IAC++H KY S +S+T Sbjct: 71 LKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSST 130 Query: 441 YKADGENCKITYGSGAISGFFSNDNVLV------GDLVVKNQKFIEATRETSVSF 587 Y +G + I YGSG++SG+ S D V V G + V+ Q F EAT++ V F Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVF 185
>CATEB_XENLA (Q805F2) Cathepsin E-B precursor (EC 3.4.23.34)| Length = 397 Score = 117 bits (293), Expect = 2e-26 Identities = 55/116 (47%), Positives = 80/116 (68%) Frame = +3 Query: 240 NSDSDIVPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKY 419 N + PL++Y++ QY+G I +GTPPQNFTVIFDTGSSNLWVPS C S AC H ++ Sbjct: 58 NDQAPSEPLINYMDVQYFGEISIGTPPQNFTVIFDTGSSNLWVPSVYC-ISPACAQHNRF 116 Query: 420 RSSRSTTYKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEATRETSVSF 587 + S+TY+++G N + YG+G++SG D+V V ++V+NQ+F E+ E +F Sbjct: 117 QPQLSSTYESNGNNFSLQYGTGSLSGVIGIDSVTVEGILVQNQQFGESVSEPGSTF 172
>RENI1_MOUSE (P06281) Renin-1 precursor (EC 3.4.23.15) (Angiotensinogenase)| (Kidney renin) Length = 402 Score = 117 bits (292), Expect = 3e-26 Identities = 60/111 (54%), Positives = 74/111 (66%), Gaps = 1/111 (0%) Frame = +3 Query: 258 VPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHPKYRSSRS 434 V L +YLNTQYYG IG+GTPPQ F VIFDTGS+NLWVPS+KC +AC +H Y SS S Sbjct: 74 VVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDS 133 Query: 435 TTYKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEATRETSVSF 587 ++Y +G + I YGSG + GF S D+V VG + V Q F E T + F Sbjct: 134 SSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITV-TQTFGEVTELPLIPF 183
>CATD_HUMAN (P07339) Cathepsin D precursor (EC 3.4.23.5) [Contains: Cathepsin D| light chain; Cathepsin D heavy chain] Length = 412 Score = 117 bits (292), Expect = 3e-26 Identities = 59/120 (49%), Positives = 79/120 (65%), Gaps = 12/120 (10%) Frame = +3 Query: 264 LVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHPKYRSSRSTT 440 L +Y++ QYYG IG+GTPPQ FTV+FDTGSSNLWVPS C IAC++H KY S +S+T Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130 Query: 441 YKADGENCKITYGSGAISGFFSNDNVLV-----------GDLVVKNQKFIEATRETSVSF 587 Y +G + I YGSG++SG+ S D V V G + V+ Q F EAT++ ++F Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITF 190
>RENI2_MOUSE (P00796) Renin-2 precursor (EC 3.4.23.15) (Angiotensinogenase)| (Submandibular gland renin) [Contains: Renin-2 heavy chain; Renin-2 light chain] Length = 401 Score = 116 bits (290), Expect = 5e-26 Identities = 59/111 (53%), Positives = 75/111 (67%), Gaps = 1/111 (0%) Frame = +3 Query: 258 VPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHPKYRSSRS 434 V L +YLN+QYYG IG+GTPPQ F VIFDTGS+NLWVPS+KC +AC +H Y SS S Sbjct: 73 VVLTNYLNSQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDS 132 Query: 435 TTYKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEATRETSVSF 587 ++Y +G++ I YGSG + GF S D+V VG + V Q F E T + F Sbjct: 133 SSYMENGDDFTIHYGSGRVKGFLSQDSVTVGGITV-TQTFGEVTELPLIPF 182
>CATD_CANFA (Q4LAL9) Cathepsin D precursor (EC 3.4.23.5)| Length = 410 Score = 115 bits (289), Expect = 7e-26 Identities = 58/118 (49%), Positives = 78/118 (66%), Gaps = 10/118 (8%) Frame = +3 Query: 264 LVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHPKYRSSRSTT 440 L +Y++ QYYG IG+GTPPQ FTV+FDTGSSNLWVPS C IAC++H KY S +S+T Sbjct: 71 LRNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSGKSST 130 Query: 441 YKADGENCKITYGSGAISGFFSNDNVLV---------GDLVVKNQKFIEATRETSVSF 587 Y +G + I YGSG++SG+ S D V V + V+ Q F EAT++ ++F Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSALSGLAGIKVERQTFGEATKQPGITF 188
>CATEA_XENLA (Q805F3) Cathepsin E-A precursor (EC 3.4.23.34)| Length = 397 Score = 115 bits (287), Expect = 1e-25 Identities = 54/116 (46%), Positives = 79/116 (68%) Frame = +3 Query: 240 NSDSDIVPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKY 419 N + PL++Y++ +Y+G I +GTPPQNFTVIFDTGSSNLWVPS C S AC H ++ Sbjct: 58 NDQAPSEPLINYMDVEYFGEISVGTPPQNFTVIFDTGSSNLWVPSVYC-ISQACAQHDRF 116 Query: 420 RSSRSTTYKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEATRETSVSF 587 + S+TY+++G N + YG+G++SG D V V ++V+NQ+F E+ E +F Sbjct: 117 QPQLSSTYESNGNNFSLQYGTGSLSGVIGIDAVTVEGILVQNQQFGESVSEPGSTF 172
>CATD_PIG (P00795) Cathepsin D precursor (EC 3.4.23.5) [Contains: Cathepsin D| light chain; Cathepsin D heavy chain] Length = 345 Score = 115 bits (287), Expect = 1e-25 Identities = 57/119 (47%), Positives = 79/119 (66%), Gaps = 11/119 (9%) Frame = +3 Query: 264 LVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHPKYRSSRSTT 440 L +Y++ QYYG IG+GTPPQ FTV+FDTGSSNLWVPS C IAC++H KY S +S+T Sbjct: 7 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSGKSST 66 Query: 441 YKADGENCKITYGSGAISGFFSNDNVL----------VGDLVVKNQKFIEATRETSVSF 587 Y +G I YGSG++SG+ S+ + + VG + V+ Q F EAT++ ++F Sbjct: 67 YVKNGTTFAIHYGSGSLSGYLSSQDTVSVPCNSALSGVGGIKVERQTFGEATKQPGLTF 125
>NAPSA_HUMAN (O96009) Napsin-A precursor (EC 3.4.23.-) (Napsin-1) (NAPA)| (TA01/TA02) (Aspartyl protease 4) (Asp 4) (ASP4) Length = 420 Score = 114 bits (286), Expect = 2e-25 Identities = 63/153 (41%), Positives = 89/153 (58%), Gaps = 4/153 (2%) Frame = +3 Query: 141 LLRINLNKRSLTHESLAAAKAARQYGALRLKSGNSDSD---IVPLVDYLNTQYYGVIGLG 311 L+RI L++ L + R+ L S D VPL +Y + QY+G IGLG Sbjct: 26 LIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQYFGEIGLG 85 Query: 312 TPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHPKYRSSRSTTYKADGENCKITYGSGA 488 TPPQNFTV FDTGSSNLWVPS +C +FS+ C+LH ++ S++++A+G I YG+G Sbjct: 86 TPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFAIQYGTGR 145 Query: 489 ISGFFSNDNVLVGDLVVKNQKFIEATRETSVSF 587 + G S D + +G + + F EA E S+ F Sbjct: 146 VDGILSEDKLTIGGIKGASVIFGEALWEPSLVF 178
>CATD_SHEEP (Q9MZS8) Cathepsin D precursor (EC 3.4.23.5) (Fragment)| Length = 365 Score = 114 bits (286), Expect = 2e-25 Identities = 58/118 (49%), Positives = 76/118 (64%), Gaps = 10/118 (8%) Frame = +3 Query: 264 LVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHPKYRSSRSTT 440 L +Y++ QYYG IG+GTPPQ FTV+FDTGS+NLWVPS C IAC++H KY S +S+T Sbjct: 46 LTNYMDAQYYGEIGIGTPPQCFTVVFDTGSANLWVPSIHCKLLDIACWVHHKYNSDKSST 105 Query: 441 YKADGENCKITYGSGAISGFFSNDNVLV---------GDLVVKNQKFIEATRETSVSF 587 Y +G I YGSG++SG+ S D V V G + V+ Q F EA ++ V F Sbjct: 106 YVKNGTTFDIHYGSGSLSGYLSQDTVSVPCNPSSSSPGGVTVQRQTFGEAIKQPGVVF 163
>RENI_PANTR (P60016) Renin precursor (EC 3.4.23.15) (Angiotensinogenase)| Length = 406 Score = 114 bits (285), Expect = 2e-25 Identities = 69/177 (38%), Positives = 99/177 (55%), Gaps = 3/177 (1%) Frame = +3 Query: 66 LLLLVTTCLWAISCAVPHHASSRDGLLRINLNKRSLTHESLAAAKAARQYGA--LRLKSG 239 LLLL +C + + R L R+ + SL + A+ ++ RL G Sbjct: 13 LLLLWGSCTFGLPTDTT--TFKRIFLKRMPSIRESLKERGVDMARLGPEWSQPMKRLTLG 70 Query: 240 NSDSDIVPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHPK 416 N+ S ++ L +Y++TQYYG IG+GTPPQ F V+FDTGSSN+WVPSSKC AC H Sbjct: 71 NTTSSVI-LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKL 129 Query: 417 YRSSRSTTYKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEATRETSVSF 587 + +S S++YK +G + Y +G +SGF S D + VG + V Q F E T ++ F Sbjct: 130 FDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVTEMPALPF 185
>RENI_MACMU (Q6DLW5) Renin precursor (EC 3.4.23.15) (Angiotensinogenase)| Length = 406 Score = 114 bits (285), Expect = 2e-25 Identities = 69/177 (38%), Positives = 99/177 (55%), Gaps = 3/177 (1%) Frame = +3 Query: 66 LLLLVTTCLWAISCAVPHHASSRDGLLRINLNKRSLTHESLAAAKAARQYGA--LRLKSG 239 LLLL +C + + R L R+ + SL + A+ ++ RL G Sbjct: 13 LLLLWGSCTFGLPTDTT--TFKRIFLKRMPSIRESLKERGVDMARLGPEWSQPMKRLALG 70 Query: 240 NSDSDIVPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHPK 416 N+ S ++ L +Y++TQYYG IG+GTPPQ F V+FDTGSSN+WVPSSKC AC H Sbjct: 71 NTTSSVI-LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKL 129 Query: 417 YRSSRSTTYKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEATRETSVSF 587 + +S S++YK +G + Y +G +SGF S D + VG + V Q F E T ++ F Sbjct: 130 FDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVTEMPALPF 185
>RENI_MACFA (Q6DLS0) Renin precursor (EC 3.4.23.15) (Angiotensinogenase)| Length = 406 Score = 114 bits (285), Expect = 2e-25 Identities = 69/177 (38%), Positives = 99/177 (55%), Gaps = 3/177 (1%) Frame = +3 Query: 66 LLLLVTTCLWAISCAVPHHASSRDGLLRINLNKRSLTHESLAAAKAARQYGA--LRLKSG 239 LLLL +C + + R L R+ + SL + A+ ++ RL G Sbjct: 13 LLLLWGSCTFGLPTDTT--TFKRIFLKRMPSIRESLKERGVDMARLGPEWSQPMKRLALG 70 Query: 240 NSDSDIVPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHPK 416 N+ S ++ L +Y++TQYYG IG+GTPPQ F V+FDTGSSN+WVPSSKC AC H Sbjct: 71 NTTSSVI-LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKL 129 Query: 417 YRSSRSTTYKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEATRETSVSF 587 + +S S++YK +G + Y +G +SGF S D + VG + V Q F E T ++ F Sbjct: 130 FDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVTEMPALPF 185
>RENI_HUMAN (P00797) Renin precursor (EC 3.4.23.15) (Angiotensinogenase)| Length = 406 Score = 114 bits (285), Expect = 2e-25 Identities = 69/177 (38%), Positives = 99/177 (55%), Gaps = 3/177 (1%) Frame = +3 Query: 66 LLLLVTTCLWAISCAVPHHASSRDGLLRINLNKRSLTHESLAAAKAARQYGA--LRLKSG 239 LLLL +C + + R L R+ + SL + A+ ++ RL G Sbjct: 13 LLLLWGSCTFGLPTDTT--TFKRIFLKRMPSIRESLKERGVDMARLGPEWSQPMKRLTLG 70 Query: 240 NSDSDIVPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHPK 416 N+ S ++ L +Y++TQYYG IG+GTPPQ F V+FDTGSSN+WVPSSKC AC H Sbjct: 71 NTTSSVI-LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKL 129 Query: 417 YRSSRSTTYKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEATRETSVSF 587 + +S S++YK +G + Y +G +SGF S D + VG + V Q F E T ++ F Sbjct: 130 FDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVTEMPALPF 185
>CATD_MOUSE (P18242) Cathepsin D precursor (EC 3.4.23.5)| Length = 410 Score = 113 bits (283), Expect = 4e-25 Identities = 59/118 (50%), Positives = 77/118 (65%), Gaps = 10/118 (8%) Frame = +3 Query: 264 LVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHPKYRSSRSTT 440 L +YL+ QYYG IG+GTPPQ FTV+FDTGSSNLWVPS C IAC++H KY S +S+T Sbjct: 71 LKNYLDAQYYGDIGIGTPPQCFTVVFDTGSSNLWVPSIHCKILDIACWVHHKYNSDKSST 130 Query: 441 YKADGENCKITYGSGAISGFFSNDNVLV---------GDLVVKNQKFIEATRETSVSF 587 Y +G + I YGSG++SG+ S D V V + V+ Q F EAT++ + F Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDQSKARGIKVEKQIFGEATKQPGIVF 188
>RENI_RAT (P08424) Renin precursor (EC 3.4.23.15) (Angiotensinogenase)| Length = 402 Score = 113 bits (282), Expect = 5e-25 Identities = 74/179 (41%), Positives = 101/179 (56%), Gaps = 5/179 (2%) Frame = +3 Query: 66 LLLLVTTCLWAISCAVPHHASSRDGLL--RINLNKRSLTHESLAAAKAARQYGALRLKSG 239 LLLL T+C S ++P +S +L ++ + L + + + ++G KS Sbjct: 11 LLLLWTSC----SFSLPTDTASFGRILLKKMPSVREILEERGVDMTRISAEWGEFIKKSS 66 Query: 240 --NSDSDIVPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLH 410 N S +V L +YL+TQYYG IG+GTP Q F VIFDTGS+NLWVPS+KC AC +H Sbjct: 67 FTNVTSPVV-LTNYLDTQYYGEIGIGTPSQTFKVIFDTGSANLWVPSTKCGPLYTACEIH 125 Query: 411 PKYRSSRSTTYKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEATRETSVSF 587 Y SS S++Y +G I YGSG + GF S D V VG ++V Q F E T + F Sbjct: 126 NLYDSSESSSYMENGTEFTIHYGSGKVKGFLSQDVVTVGGIIV-TQTFGEVTELPLIPF 183
>CATD_BOVIN (P80209) Cathepsin D precursor (EC 3.4.23.5)| Length = 390 Score = 113 bits (282), Expect = 5e-25 Identities = 58/118 (49%), Positives = 75/118 (63%), Gaps = 10/118 (8%) Frame = +3 Query: 264 LVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKC-YFSIACYLHPKYRSSRSTT 440 L +Y++ QYYG IG+GTPPQ FTV+FDTGS+NLWVPS C IAC+ H KY S +S+T Sbjct: 51 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSANLWVPSIHCKLLDIACWTHRKYNSDKSST 110 Query: 441 YKADGENCKITYGSGAISGFFSNDNVLV---------GDLVVKNQKFIEATRETSVSF 587 Y +G I YGSG++SG+ S D V V G + V+ Q F EA ++ V F Sbjct: 111 YVKNGTTFDIHYGSGSLSGYLSQDTVSVPCNPSSSSPGGVTVQRQTFGEAIKQPGVVF 168
>RENI_SHEEP (P52115) Renin precursor (EC 3.4.23.15) (Angiotensinogenase)| Length = 400 Score = 112 bits (281), Expect = 6e-25 Identities = 65/138 (47%), Positives = 82/138 (59%), Gaps = 3/138 (2%) Frame = +3 Query: 162 KRSLTHESLAAAKAARQYGALR--LKSGNSDSDIVPLVDYLNTQYYGVIGLGTPPQNFTV 335 + SL + A+ ++ L L GN S +V L +YL+TQYYG IG+GTPPQ F V Sbjct: 37 RESLKERGVDMAQLGAEWSQLTKTLSFGNRTSPVV-LTNYLDTQYYGEIGIGTPPQTFKV 95 Query: 336 IFDTGSSNLWVPSSKCY-FSIACYLHPKYRSSRSTTYKADGENCKITYGSGAISGFFSND 512 IFDTGS+NLWVPS+KC AC +H Y S S++Y +G I YGSG + GF S D Sbjct: 96 IFDTGSANLWVPSTKCSPLYTACEIHSLYDSLESSSYVENGTEFTIYYGSGKVKGFLSQD 155 Query: 513 NVLVGDLVVKNQKFIEAT 566 V VG + V Q F E T Sbjct: 156 LVTVGGITV-TQTFGEVT 172
>CATE_RANCA (Q800A0) Cathepsin E precursor (EC 3.4.23.34)| Length = 397 Score = 112 bits (281), Expect = 6e-25 Identities = 62/158 (39%), Positives = 90/158 (56%), Gaps = 8/158 (5%) Frame = +3 Query: 138 GLLRINLNKRSLTHESLAA--------AKAARQYGALRLKSGNSDSDIVPLVDYLNTQYY 293 G++R+ L ++ + L K ++ L + ++ PL++YL+ +Y+ Sbjct: 16 GIIRVPLKRQKSMRKILKEKGKLSHLWTKQGNEFLQLSDSCSSPETASEPLMNYLDVEYF 75 Query: 294 GVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSSRSTTYKADGENCKIT 473 G I +GTPPQ FTVIFDTGSSNLWVPS C S AC H +YR S STTY ++GE I Sbjct: 76 GQISIGTPPQQFTVIFDTGSSNLWVPSIYC-TSQACTKHNRYRPSESTTYVSNGEAFFIQ 134 Query: 474 YGSGAISGFFSNDNVLVGDLVVKNQKFIEATRETSVSF 587 YG+G ++G D V V + V++Q F E+ E +F Sbjct: 135 YGTGNLTGILGIDQVTVQGITVQSQTFAESVSEPGSTF 172
>CATE_MOUSE (P70269) Cathepsin E precursor (EC 3.4.23.34)| Length = 397 Score = 112 bits (281), Expect = 6e-25 Identities = 55/109 (50%), Positives = 72/109 (66%) Frame = +3 Query: 261 PLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSSRSTT 440 PL++YL+ +Y+G I +GTPPQNFTVIFDTGSSNLWVPS C S AC HP + S+S T Sbjct: 70 PLINYLDMEYFGTISIGTPPQNFTVIFDTGSSNLWVPSVYC-TSPACKAHPVFHPSQSDT 128 Query: 441 YKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEATRETSVSF 587 Y G + I YG+G+++G D V V L V Q+F E+ +E +F Sbjct: 129 YTEVGNHFSIQYGTGSLTGIIGADQVSVEGLTVDGQQFGESVKEPGQTF 177
>PEPA1_RABIT (P28712) Pepsin II-1 precursor (EC 3.4.23.1) (Pepsin A)| Length = 387 Score = 112 bits (279), Expect = 1e-24 Identities = 67/175 (38%), Positives = 98/175 (56%), Gaps = 3/175 (1%) Frame = +3 Query: 72 LLVTTCLWAISCAVPHHASSRDGLLRINLNKRSLTHESLAAAK---AARQYGALRLKSGN 242 LL+ L C V R LR NL ++ L + L A + + S + Sbjct: 4 LLLLGLLALSECIVHKVPLVRKKSLRKNLIEKGLLQDYLKTHTPNLATKYFPKETFASVS 63 Query: 243 SDSDIVPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYR 422 ++S L +YL+ +Y+G I +GTPPQ FTVIFDTGSSNLWVPS+ C S+AC+LH ++ Sbjct: 64 TES----LENYLDAEYFGTISIGTPPQEFTVIFDTGSSNLWVPSTYC-SSLACFLHKRFN 118 Query: 423 SSRSTTYKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEATRETSVSF 587 S+T++A E ITYG+G+++G D V VG++ NQ F + E ++F Sbjct: 119 PDDSSTFQATSETLSITYGTGSMTGILGYDTVKVGNIEDTNQIFGLSKTEPGITF 173
>CATE_RABIT (P43159) Cathepsin E precursor (EC 3.4.23.34)| Length = 396 Score = 111 bits (278), Expect = 1e-24 Identities = 54/109 (49%), Positives = 73/109 (66%) Frame = +3 Query: 261 PLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSSRSTT 440 PL++YL+ +Y+G I +G+PPQNFTVIFDT SSNLWVPS C S AC +HP++R S+S T Sbjct: 69 PLINYLDMEYFGTISIGSPPQNFTVIFDTVSSNLWVPSVYC-TSPACQMHPQFRPSQSNT 127 Query: 441 YKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEATRETSVSF 587 Y G I YG+G+++G D V V L V Q+F E+ +E +F Sbjct: 128 YSEVGTPFSIAYGTGSLTGIIGADQVSVQGLTVVGQQFGESVKEPGQTF 176
>CATE_CAVPO (P25796) Cathepsin E precursor (EC 3.4.23.34)| Length = 391 Score = 111 bits (278), Expect = 1e-24 Identities = 54/109 (49%), Positives = 73/109 (66%) Frame = +3 Query: 261 PLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSSRSTT 440 PL++YL+ +Y+G I +G+PPQNFTVIFDTGSSNLWVPS C S AC HP + S S+T Sbjct: 65 PLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC-TSPACQTHPVFHPSLSST 123 Query: 441 YKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEATRETSVSF 587 Y+ G + I YG+G+++G D V V L V Q+F E+ +E +F Sbjct: 124 YREVGNSFSIQYGTGSLTGIIGADQVSVEGLTVVGQQFGESVQEPGKTF 172
>RENI_CALJA (Q9TSZ1) Renin precursor (EC 3.4.23.15) (Angiotensinogenase)| Length = 400 Score = 111 bits (277), Expect = 2e-24 Identities = 63/149 (42%), Positives = 87/149 (58%), Gaps = 2/149 (1%) Frame = +3 Query: 147 RINLNKRSLTHESLAAAKA-ARQYGALRLKSGNSDSDIVPLVDYLNTQYYGVIGLGTPPQ 323 RI+L + ESL + G R+ N S ++ L +Y++TQYYG IG+GTPPQ Sbjct: 33 RISLKRMPSIRESLKERGVDMARLGPERMALVNITSSVI-LTNYMDTQYYGEIGIGTPPQ 91 Query: 324 NFTVIFDTGSSNLWVPSSKC-YFSIACYLHPKYRSSRSTTYKADGENCKITYGSGAISGF 500 F V+FDTGSSN+WVPSSKC AC H + +S S++YK +G + Y +G +SGF Sbjct: 92 TFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGF 151 Query: 501 FSNDNVLVGDLVVKNQKFIEATRETSVSF 587 S D + VG + V Q F E T ++ F Sbjct: 152 LSQDVITVGGITV-TQTFGEVTEMPALPF 179
>CATE_RAT (P16228) Cathepsin E precursor (EC 3.4.23.34)| Length = 398 Score = 109 bits (273), Expect = 5e-24 Identities = 56/120 (46%), Positives = 78/120 (65%), Gaps = 1/120 (0%) Frame = +3 Query: 231 KSGNSDSDI-VPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYL 407 +S N D I PL++YL+ +Y+G + +G+P QNFTVIFDTGSSNLWVPS C S AC Sbjct: 60 ESCNVDKGINEPLINYLDMEYFGTVSIGSPSQNFTVIFDTGSSNLWVPSVYC-TSPACKA 118 Query: 408 HPKYRSSRSTTYKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEATRETSVSF 587 HP + S+S+TY G + I YG+G+++G D V V L V+ Q+F E+ +E +F Sbjct: 119 HPVFHPSQSSTYMEVGNHFSIQYGTGSLTGIIGADQVSVEGLTVEGQQFGESVKEPGQTF 178
>PEPC_HUMAN (P20142) Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C)| Length = 388 Score = 109 bits (272), Expect = 7e-24 Identities = 62/173 (35%), Positives = 94/173 (54%) Frame = +3 Query: 69 LLLVTTCLWAISCAVPHHASSRDGLLRINLNKRSLTHESLAAAKAARQYGALRLKSGNSD 248 +++V CL + AV + +R + ++ L E L K A + + G+ Sbjct: 4 MVVVLVCLQLLEAAVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDP---AWKYRFGDLS 60 Query: 249 SDIVPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSS 428 P+ Y++ Y+G I +GTPPQNF V+FDTGSSNLWVPS C S AC H ++ S Sbjct: 61 VTYEPMA-YMDAAYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCQ-SQACTSHSRFNPS 118 Query: 429 RSTTYKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEATRETSVSF 587 S+TY +G+ + YGSG+++GFF D + V + V NQ+F + E +F Sbjct: 119 ESSTYSTNGQTFSLQYGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNF 171
>PEPA2_RABIT (P27821) Pepsin II-2/3 precursor (EC 3.4.23.1) (Pepsin A)| Length = 387 Score = 108 bits (271), Expect = 9e-24 Identities = 52/106 (49%), Positives = 72/106 (67%) Frame = +3 Query: 270 DYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSSRSTTYKA 449 +YL+ +Y+G I +GTPPQ+FTVIFDTGSSNLWVPS+ C S+AC LH ++ S+TY+ Sbjct: 69 NYLDAEYFGTISIGTPPQDFTVIFDTGSSNLWVPSTYC-SSLACALHKRFNPEDSSTYQG 127 Query: 450 DGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEATRETSVSF 587 E ITYG+G+++G D V VG + NQ F + E S++F Sbjct: 128 TSETLSITYGTGSMTGILGYDTVKVGSIEDTNQIFGLSKTEPSLTF 173
>PEPA4_MACFU (P27678) Pepsin A-4 precursor (EC 3.4.23.1) (Pepsin I/II)| Length = 388 Score = 108 bits (270), Expect = 1e-23 Identities = 64/142 (45%), Positives = 83/142 (58%) Frame = +3 Query: 129 SRDGLLRINLNKRSLTHESLAAAKAARQYGALRLKSGNSDSDIVPLVDYLNTQYYGVIGL 308 S GLL+ L K +L A+K Q A L D PL +YL+ +Y+G IG+ Sbjct: 33 SEHGLLKDFLKKHNLN----PASKYFPQAEAPTL------IDEQPLENYLDVEYFGTIGI 82 Query: 309 GTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSSRSTTYKADGENCKITYGSGA 488 GTP QNFTV+FDTGSSNLWVPS CY S+AC H + S+TY+A + ITYG+G+ Sbjct: 83 GTPAQNFTVVFDTGSSNLWVPSVYCY-SLACMDHNLFNPQDSSTYRATSKTVSITYGTGS 141 Query: 489 ISGFFSNDNVLVGDLVVKNQKF 554 ++G D V VG + NQ F Sbjct: 142 MTGILGYDTVKVGGISDTNQIF 163
>PEPC_CALJA (Q9N2D3) Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C)| Length = 388 Score = 108 bits (269), Expect = 1e-23 Identities = 62/175 (35%), Positives = 93/175 (53%), Gaps = 2/175 (1%) Frame = +3 Query: 69 LLLVTTCLWAISCAVPHHASSRDGLLRINLNKRSLTHESLAAAK--AARQYGALRLKSGN 242 +++ CL + V + +R + ++ L E L K AR+Y L Sbjct: 4 MVVAFICLQLLEATVVKVPLKKFKSIRETMKEKGLLWEFLKTHKHDPARKYRVSDLSVSY 63 Query: 243 SDSDIVPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYR 422 +DY++ Y+G I +GTPPQNF V+FDTGSSNLWVPS C S AC H ++ Sbjct: 64 EP------MDYMDAAYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCQ-SQACTSHSRFN 116 Query: 423 SSRSTTYKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEATRETSVSF 587 S S+TY ++G+ + YGSG+++GFF D + V + V NQ+F + E +F Sbjct: 117 PSASSTYSSNGQTFSLQYGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNF 171
>PEPA4_RABIT (P28713) Pepsin II-4 precursor (EC 3.4.23.1) (Pepsin A)| Length = 387 Score = 108 bits (269), Expect = 1e-23 Identities = 52/108 (48%), Positives = 72/108 (66%) Frame = +3 Query: 264 LVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSSRSTTY 443 L +YL+ +Y+G I +GTPPQ+FTVIFDTGSSNLWVPS+ C S+AC LH ++ S+TY Sbjct: 67 LENYLDAEYFGTISIGTPPQDFTVIFDTGSSNLWVPSTYC-SSLACALHKRFNPEDSSTY 125 Query: 444 KADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEATRETSVSF 587 + E ITYG+G+++G D V VG + NQ F + E ++F Sbjct: 126 QGTSETLSITYGTGSMTGILGYDTVKVGSIEDTNQIFGLSKTEPGLTF 173
>PEPA_CALJA (Q9N2D4) Pepsin A precursor (EC 3.4.23.1)| Length = 387 Score = 107 bits (267), Expect = 3e-23 Identities = 64/162 (39%), Positives = 87/162 (53%) Frame = +3 Query: 69 LLLVTTCLWAISCAVPHHASSRDGLLRINLNKRSLTHESLAAAKAARQYGALRLKSGNSD 248 L+ ++ CL+ +S S R L+ L K L + +L A G N Sbjct: 9 LVALSECLYKVSLI--KKKSLRKNLIEHGLLKDFLKNNTLDPASKYFPQGEAATMIANQ- 65 Query: 249 SDIVPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSS 428 PLV+YL+ +Y+G IG+GTP Q FTVIFDTGSSNLWVPS C S AC H ++ Sbjct: 66 ----PLVNYLDMEYFGTIGIGTPAQEFTVIFDTGSSNLWVPSIYC-SSPACTNHNRFNPQ 120 Query: 429 RSTTYKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKF 554 S+TY+A + I YG+G+++G D V VG + NQ F Sbjct: 121 ESSTYQATSQTLSIAYGTGSMTGILGYDTVQVGGIADTNQIF 162
>PEPA3_RABIT (P27822) Pepsin-3 precursor (EC 3.4.23.1) (Pepsin III) (Pepsin A)| Length = 387 Score = 107 bits (266), Expect = 3e-23 Identities = 54/104 (51%), Positives = 73/104 (70%), Gaps = 3/104 (2%) Frame = +3 Query: 252 DIVP---LVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYR 422 D VP L +YL+T+Y+G IG+GTP Q+FTVIFDTGSSNLWVPS C S AC +H ++ Sbjct: 60 DSVPTETLENYLDTEYFGTIGIGTPAQDFTVIFDTGSSNLWVPSVYC-SSAACSVHNQFN 118 Query: 423 SSRSTTYKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKF 554 S+T++A E+ ITYG+G+++GF D V VG++ NQ F Sbjct: 119 PEDSSTFQATSESLSITYGTGSMTGFLGYDTVKVGNIEDTNQIF 162
>PEPE_CHICK (P16476) Embryonic pepsinogen precursor (EC 3.4.23.-)| Length = 383 Score = 106 bits (265), Expect = 4e-23 Identities = 54/109 (49%), Positives = 70/109 (64%) Frame = +3 Query: 261 PLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSSRSTT 440 PL++ L+ +YYG I +GTPPQ+FTV+FDTGSSNLWVPS C S AC H + S+S+T Sbjct: 67 PLLNTLDMEYYGTISIGTPPQDFTVVFDTGSSNLWVPSVSC-TSPACQSHQMFNPSQSST 125 Query: 441 YKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEATRETSVSF 587 YK+ G+N I YG+G + G D V V L+ NQ F +T E F Sbjct: 126 YKSTGQNLSIHYGTGDMEGTVGCDTVTVASLMDTNQLFGLSTSEPGQFF 174
>CATE_HUMAN (P14091) Cathepsin E precursor (EC 3.4.23.34)| Length = 401 Score = 106 bits (264), Expect = 6e-23 Identities = 54/114 (47%), Positives = 74/114 (64%), Gaps = 5/114 (4%) Frame = +3 Query: 261 PLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSSRSTT 440 PL++YL+ +Y+G I +G+PPQNFTVIFDTGSSNLWVPS C S AC H +++ S+S+T Sbjct: 69 PLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC-TSPACKTHSRFQPSQSST 127 Query: 441 YKADGENCKITYGSGAISGFFSNDNV-----LVGDLVVKNQKFIEATRETSVSF 587 Y G++ I YG+G++SG D V V L V Q+F E+ E +F Sbjct: 128 YSQPGQSFSIQYGTGSLSGIIGADQVSAFATQVEGLTVVGQQFGESVTEPGQTF 181
>PEPA_BOVIN (P00792) Pepsin A precursor (EC 3.4.23.1)| Length = 372 Score = 105 bits (262), Expect = 1e-22 Identities = 52/98 (53%), Positives = 67/98 (68%) Frame = +3 Query: 261 PLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSSRSTT 440 PL +YL+T+Y+G IG+GTP Q+FTVIFDTGSSNLWVPS C S AC H ++ S+T Sbjct: 51 PLQNYLDTEYFGTIGIGTPAQDFTVIFDTGSSNLWVPSIYC-SSEACTNHNRFNPQDSST 109 Query: 441 YKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKF 554 Y+A E ITYG+G+++G D V VG + NQ F Sbjct: 110 YEATSETLSITYGTGSMTGILGYDTVQVGGISDTNQIF 147
>PEPC_SUNMU (P81498) Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C-1)| Length = 389 Score = 105 bits (261), Expect = 1e-22 Identities = 59/173 (34%), Positives = 94/173 (54%) Frame = +3 Query: 69 LLLVTTCLWAISCAVPHHASSRDGLLRINLNKRSLTHESLAAAKAARQYGALRLKSGNSD 248 +++ CL + V + +R NL ++ L + L K A + G+ Sbjct: 4 MVVALVCLQLLEAKVTKVTLKKFKSIRENLREQGLLEDFL---KTNHYDPAQKYHFGDFS 60 Query: 249 SDIVPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSS 428 P+ Y++ Y+G I +GTPPQNF V+FDTGSSNLWVPS C S AC H ++ + Sbjct: 61 VAYEPMA-YMDASYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCQ-SQACTGHARFNPN 118 Query: 429 RSTTYKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEATRETSVSF 587 +S+TY +G+ + YGSG+++GFF D + V ++ V +Q+F + E +F Sbjct: 119 QSSTYSTNGQTFSLQYGSGSLTGFFGYDTMTVQNIKVPHQEFGLSQNEPGTNF 171
>PEPC_MACFU (P03955) Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C)| (Fragment) Length = 377 Score = 105 bits (261), Expect = 1e-22 Identities = 49/105 (46%), Positives = 68/105 (64%) Frame = +3 Query: 273 YLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSSRSTTYKAD 452 Y++ Y+G I +GTPPQNF V+FDTGSSNLWVPS C S AC H ++ S S+TY + Sbjct: 57 YMDAAYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCQ-SQACTSHSRFNPSESSTYSTN 115 Query: 453 GENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEATRETSVSF 587 G+ + YGSG+++GFF D + V + V NQ+F + E +F Sbjct: 116 GQTFSLQYGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNF 160
>PEPC_RABIT (Q9GMY2) Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C)| Length = 388 Score = 105 bits (261), Expect = 1e-22 Identities = 63/173 (36%), Positives = 93/173 (53%) Frame = +3 Query: 69 LLLVTTCLWAISCAVPHHASSRDGLLRINLNKRSLTHESLAAAKAARQYGALRLKSGNSD 248 LL+ CL + AV + +R L ++ L E L K AL+ + G+ Sbjct: 4 LLVALVCLHLLEAAVIKVPLRKFKSIRETLKEKGLLKEFLNTHKYDP---ALKYRFGDFS 60 Query: 249 SDIVPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSS 428 P+ DYL+ Y+G I +GTP QNF V+FDTGSSNLWVPS C S AC H ++ S Sbjct: 61 VTYEPM-DYLDAAYFGEISIGTPSQNFLVLFDTGSSNLWVPSVYCQ-SEACTTHNRFNPS 118 Query: 429 RSTTYKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEATRETSVSF 587 +S+T+ + + YGSG+++GFF D + ++ V NQ+F + E +F Sbjct: 119 KSSTFYTYDQTFSLEYGSGSLTGFFGYDTFTIQNIEVPNQEFGLSETEPGTNF 171
>ASP3_CAEEL (P55956) Aspartic protease 3 precursor (EC 3.4.23.-)| Length = 398 Score = 105 bits (261), Expect = 1e-22 Identities = 62/154 (40%), Positives = 82/154 (53%), Gaps = 7/154 (4%) Frame = +3 Query: 147 RINLNKRSLTHESLAAAKAARQYGALRLKS--GNSDSDIVPLVDYLNTQYYGVIGLGTPP 320 RI L KR+ T E A + N D+ L DY N QYYG + +GTPP Sbjct: 20 RIKLEKRTYTREQYKFGSIQEHLKAKYVPGYIPNKDAFNEGLSDYSNAQYYGPVTIGTPP 79 Query: 321 QNFTVIFDTGSSNLWVPSSKCYF-SIACYLHPKYRSSRSTTYKADGENCKITYGSGAISG 497 QNF V+FDTGSSNLWVP + C F IAC +H ++ +S++ A G + +I YG+G++ G Sbjct: 80 QNFQVLFDTGSSNLWVPCANCPFGDIACRMHNRFDCKKSSSCTATGASFEIQYGTGSMKG 139 Query: 498 FFSNDNVLVGD----LVVKNQKFIEATRETSVSF 587 ND V G KNQ AT E ++F Sbjct: 140 TVDNDVVCFGHDTTYCTDKNQGLACATSEPGITF 173
>PEPA_HUMAN (P00790) Pepsin A precursor (EC 3.4.23.1)| Length = 388 Score = 104 bits (260), Expect = 2e-22 Identities = 62/142 (43%), Positives = 83/142 (58%) Frame = +3 Query: 129 SRDGLLRINLNKRSLTHESLAAAKAARQYGALRLKSGNSDSDIVPLVDYLNTQYYGVIGL 308 S GLL+ L K +L A K Q+ A L D PL +YL+ +Y+G IG+ Sbjct: 33 SERGLLKDFLKKHNLN----PARKYFPQWEAPTLV------DEQPLENYLDMEYFGTIGI 82 Query: 309 GTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSSRSTTYKADGENCKITYGSGA 488 GTP Q+FTV+FDTGSSNLWVPS C S+AC H ++ S+TY++ E ITYG+G+ Sbjct: 83 GTPAQDFTVVFDTGSSNLWVPSVYC-SSLACTNHNRFNPEDSSTYQSTSETVSITYGTGS 141 Query: 489 ISGFFSNDNVLVGDLVVKNQKF 554 ++G D V VG + NQ F Sbjct: 142 MTGILGYDTVQVGGISDTNQIF 163
>PEPA_RHIFE (Q9GMY7) Pepsin A precursor (EC 3.4.23.1)| Length = 386 Score = 104 bits (259), Expect = 2e-22 Identities = 58/139 (41%), Positives = 81/139 (58%), Gaps = 2/139 (1%) Frame = +3 Query: 144 LRINLNKRSLTHESLA--AAKAARQYGALRLKSGNSDSDIVPLVDYLNTQYYGVIGLGTP 317 LR NL ++ L + L + A +Y LK S PL +Y++ +Y+G IG+GTP Sbjct: 28 LRKNLMEQGLLQDYLKTHSINPASKY----LKEAASMMATQPLENYMDMEYFGTIGIGTP 83 Query: 318 PQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSSRSTTYKADGENCKITYGSGAISG 497 PQ FTVIFDTGSSNLWVPS C S AC H ++ +S+TY+ + + YG+G+++G Sbjct: 84 PQEFTVIFDTGSSNLWVPSVYC-SSPACSNHNRFNPQQSSTYQGTNQKLSVAYGTGSMTG 142 Query: 498 FFSNDNVLVGDLVVKNQKF 554 D V VG + NQ F Sbjct: 143 ILGYDTVQVGGITDTNQIF 161
>PEPA_PIG (P00791) Pepsin A precursor (EC 3.4.23.1)| Length = 386 Score = 104 bits (259), Expect = 2e-22 Identities = 65/163 (39%), Positives = 95/163 (58%), Gaps = 1/163 (0%) Frame = +3 Query: 69 LLLVTTCLWAISCAVPHHASSRDGLLRINLNKRSL-THESLAAAKAARQYGALRLKSGNS 245 L++++ CL + + S R L++ K L TH+ A+K + AL G+ Sbjct: 9 LVVLSECL--VKVPLVRKKSLRQNLIKNGKLKDFLKTHKHNPASKYFPEAAAL---IGDE 63 Query: 246 DSDIVPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRS 425 PL +YL+T+Y+G IG+GTP Q+FTVIFDTGSSNLWVPS C S+AC H ++ Sbjct: 64 -----PLENYLDTEYFGTIGIGTPAQDFTVIFDTGSSNLWVPSVYC-SSLACSDHNQFNP 117 Query: 426 SRSTTYKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKF 554 S+T++A + ITYG+G+++G D V VG + NQ F Sbjct: 118 DDSSTFEATSQELSITYGTGSMTGILGYDTVQVGGISDTNQIF 160
>PEPC_MOUSE (Q9D7R7) Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C)| Length = 392 Score = 103 bits (258), Expect = 3e-22 Identities = 49/105 (46%), Positives = 67/105 (63%) Frame = +3 Query: 273 YLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSSRSTTYKAD 452 Y++ YYG I +GTPPQNF V+FDTGSSNLWV S C S AC H +Y S+S+TY Sbjct: 71 YMDASYYGEISIGTPPQNFLVLFDTGSSNLWVSSVYCQ-SEACTTHTRYNPSKSSTYYTQ 129 Query: 453 GENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEATRETSVSF 587 G+ + YG+G+++GFF D + V + V NQ+F + E +F Sbjct: 130 GQTFSLQYGTGSLTGFFGYDTLRVQSIQVPNQEFGLSENEPGTNF 174
>PEPC_RHIFE (Q9GMY3) Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C)| Length = 389 Score = 103 bits (257), Expect = 4e-22 Identities = 48/105 (45%), Positives = 69/105 (65%) Frame = +3 Query: 273 YLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSSRSTTYKAD 452 Y++ Y+G I +GTPPQNF V+FDTGSSNLWVPS C + AC H ++ S+S+TY + Sbjct: 68 YMDAAYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCQ-TQACTGHTRFNPSQSSTYSTN 126 Query: 453 GENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEATRETSVSF 587 G+ + YGSG+++GFF D + V + V NQ+F + E +F Sbjct: 127 GQTFSLQYGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNF 171
>PAG2_BOVIN (Q28057) Pregnancy-associated glycoprotein 2 precursor (EC| 3.4.23.-) (PAG 2) Length = 376 Score = 103 bits (257), Expect = 4e-22 Identities = 53/112 (47%), Positives = 67/112 (59%) Frame = +3 Query: 219 ALRLKSGNSDSDIVPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIA 398 A RL +S I PL +YL+T Y G I +GTPPQ F V+FDTGS+NLWVP C S A Sbjct: 45 AYRLSKNDSKITIHPLRNYLDTAYVGNITIGTPPQEFRVVFDTGSANLWVPCITC-TSPA 103 Query: 399 CYLHPKYRSSRSTTYKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKF 554 CY H + S++++ G I YGSG I GF +D V +G+LV Q F Sbjct: 104 CYTHKTFNPQNSSSFREVGSPITIFYGSGIIQGFLGSDTVRIGNLVSPEQSF 155
>PEPC_SORUN (Q9GMY4) Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C)| Length = 389 Score = 102 bits (254), Expect = 8e-22 Identities = 48/105 (45%), Positives = 70/105 (66%) Frame = +3 Query: 273 YLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSSRSTTYKAD 452 YL+ Y+G I +GTPPQNF V+FDTGSSNLWVPS C S AC H ++ S+S+TY + Sbjct: 68 YLDAAYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCQ-SQACTGHARFNPSKSSTYSTN 126 Query: 453 GENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEATRETSVSF 587 G+ + YGSG+++GFF D + + ++ V +Q+F + E +F Sbjct: 127 GQTFSLQYGSGSLTGFFGYDTMTLQNIKVPHQEFGLSQNEPGENF 171
>PEPA_SUNMU (P81497) Pepsin A precursor (EC 3.4.23.1)| Length = 387 Score = 102 bits (253), Expect = 1e-21 Identities = 57/139 (41%), Positives = 81/139 (58%), Gaps = 2/139 (1%) Frame = +3 Query: 144 LRINLNKRSLTHESLAA--AKAARQYGALRLKSGNSDSDIVPLVDYLNTQYYGVIGLGTP 317 LR NL + L + LA A +Y + +D PLV+Y++ +Y+G IG+GTP Sbjct: 28 LRQNLIENGLLKDFLAKHNVNPASKYFPTEAATELADQ---PLVNYMDMEYFGTIGIGTP 84 Query: 318 PQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSSRSTTYKADGENCKITYGSGAISG 497 PQ FTVIFDTGSSNLWVPS C S AC H ++ +S+T+++ + I YG+G+++G Sbjct: 85 PQEFTVIFDTGSSNLWVPSVYC-SSPACSNHNRFNPQKSSTFQSTSQTLSIAYGTGSMTG 143 Query: 498 FFSNDNVLVGDLVVKNQKF 554 D V V + NQ F Sbjct: 144 VLGYDTVQVAGIADTNQIF 162
>PEPC_RAT (P04073) Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C)| Length = 392 Score = 102 bits (253), Expect = 1e-21 Identities = 47/105 (44%), Positives = 68/105 (64%) Frame = +3 Query: 273 YLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSSRSTTYKAD 452 Y++ Y+G I +GTPPQNF V+FDTGSSNLWV S C S AC H ++ S+S+TY + Sbjct: 71 YMDASYFGEISIGTPPQNFLVLFDTGSSNLWVSSVYCQ-SEACTTHARFNPSKSSTYYTE 129 Query: 453 GENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEATRETSVSF 587 G+ + YG+G+++GFF D + V + V NQ+F + E +F Sbjct: 130 GQTFSLQYGTGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNF 174
>PEPA2_MACFU (P27677) Pepsin A-2/A-3 precursor (EC 3.4.23.1) (Pepsin| III-2/III-1) Length = 388 Score = 101 bits (252), Expect = 1e-21 Identities = 50/101 (49%), Positives = 67/101 (66%) Frame = +3 Query: 252 DIVPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSSR 431 D PL +YL+ +Y+G IG+GTP Q+FTVIFDTGSSNLWVPS C S+AC H ++ Sbjct: 64 DEQPLENYLDMEYFGTIGIGTPAQDFTVIFDTGSSNLWVPSVYC-SSLACTNHNRFNPQD 122 Query: 432 STTYKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKF 554 S+TY++ ITYG+G+++G D V VG + NQ F Sbjct: 123 SSTYQSTSGTVSITYGTGSMTGILGYDTVQVGGISDTNQIF 163
>PAG2_PIG (Q29079) Pregnancy-associated glycoprotein 2 precursor (EC| 3.4.23.-) (PAG 2) Length = 420 Score = 100 bits (250), Expect = 2e-21 Identities = 51/109 (46%), Positives = 67/109 (61%) Frame = +3 Query: 261 PLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSSRSTT 440 PL +YL+ Y G I +GTPPQ F+V+FDTGSS+LWVPS C S AC H + S S+T Sbjct: 67 PLRNYLDMVYVGNISIGTPPQQFSVVFDTGSSDLWVPSIYCK-SKACVTHRSFNPSHSST 125 Query: 441 YKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEATRETSVSF 587 + G++ K+ YGSG +SGF D V +G L Q F + ET +F Sbjct: 126 FHDRGKSIKLEYGSGKMSGFLGQDTVRIGQLTSTGQAFGLSKEETGKAF 174
>PEPC_MONDO (Q689Z7) Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C)| Length = 391 Score = 100 bits (250), Expect = 2e-21 Identities = 47/98 (47%), Positives = 69/98 (70%) Frame = +3 Query: 261 PLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSSRSTT 440 P+ +YL++ Y+G I +GTPPQNF V+FDTGSSNLWVPS+ C S AC H ++ S+S+T Sbjct: 66 PITNYLDSFYFGEISIGTPPQNFLVLFDTGSSNLWVPSTYCQ-SQACSNHNRFSPSQSST 124 Query: 441 YKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKF 554 + G+ ++YGSG+++ D V V ++VV NQ+F Sbjct: 125 FTNGGQTYTLSYGSGSLTVVLGYDTVTVQNIVVSNQEF 162
>PEPA1_MACFU (P03954) Pepsin A-1 precursor (EC 3.4.23.1) (Pepsin III-3)| Length = 388 Score = 100 bits (250), Expect = 2e-21 Identities = 62/142 (43%), Positives = 81/142 (57%) Frame = +3 Query: 129 SRDGLLRINLNKRSLTHESLAAAKAARQYGALRLKSGNSDSDIVPLVDYLNTQYYGVIGL 308 S GLL+ L K +L A+K Q A L D PL +YL+ +Y+G IG+ Sbjct: 33 SEHGLLKDFLKKHNLN----PASKYFPQAEAPTL------IDEQPLENYLDVEYFGTIGI 82 Query: 309 GTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSSRSTTYKADGENCKITYGSGA 488 GTP Q+FTVIFDTGSSNLWVPS C S+AC H + S+TY++ ITYG+G+ Sbjct: 83 GTPAQDFTVIFDTGSSNLWVPSVYC-SSLACTNHNLFNPQDSSTYQSTSGTLSITYGTGS 141 Query: 489 ISGFFSNDNVLVGDLVVKNQKF 554 ++G D V VG + NQ F Sbjct: 142 MTGILGYDTVQVGGISDTNQIF 163
>CHYM_SHEEP (P18276) Chymosin precursor (EC 3.4.23.4) (Preprorennin)| Length = 381 Score = 100 bits (249), Expect = 3e-21 Identities = 59/143 (41%), Positives = 83/143 (58%) Frame = +3 Query: 144 LRINLNKRSLTHESLAAAKAARQYGALRLKSGNSDSDIVPLVDYLNTQYYGVIGLGTPPQ 323 LR L +R L + L +QYG SG + VPL +YL++QY+G I LGTPPQ Sbjct: 30 LRKALKERGLLEDFLQK----QQYGVSSEYSGFGEVASVPLTNYLDSQYFGKIYLGTPPQ 85 Query: 324 NFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSSRSTTYKADGENCKITYGSGAISGFF 503 FTV+FDTGSS+ WVPS C S AC H ++ +S+T++ G+ I YG+G++ G Sbjct: 86 EFTVLFDTGSSDFWVPSIYCK-SNACKNHQRFDPRKSSTFQNLGKPLSIRYGTGSMQGIL 144 Query: 504 SNDNVLVGDLVVKNQKFIEATRE 572 D V V ++V Q +T+E Sbjct: 145 GYDTVTVSNIVDIQQTVGLSTQE 167
>PEPA_CHICK (P00793) Pepsin A precursor (EC 3.4.23.1)| Length = 367 Score = 100 bits (249), Expect = 3e-21 Identities = 48/98 (48%), Positives = 65/98 (66%) Frame = +3 Query: 261 PLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSSRSTT 440 P+ +Y++ YYG I +GTP Q+F+VIFDTGSSNLWVPS C S AC H ++ S+S+T Sbjct: 50 PMTNYMDASYYGTISIGTPQQDFSVIFDTGSSNLWVPSIYCK-SSACSNHKRFDPSKSST 108 Query: 441 YKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKF 554 Y + E I YG+G++SG D V V + V+NQ F Sbjct: 109 YVSTNETVYIAYGTGSMSGILGYDTVAVSSIDVQNQIF 146
>PEPA_MACMU (P11489) Pepsin A precursor (EC 3.4.23.1)| Length = 388 Score = 100 bits (249), Expect = 3e-21 Identities = 50/101 (49%), Positives = 66/101 (65%) Frame = +3 Query: 252 DIVPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSSR 431 D PL +YL+ +Y+G IG+GTP Q+FTVIFDTGSSNLWVPS C S+AC H + Sbjct: 64 DEQPLENYLDVEYFGTIGIGTPAQDFTVIFDTGSSNLWVPSVYC-SSLACTNHNLFNPQD 122 Query: 432 STTYKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKF 554 S+TY++ ITYG+G+++G D V VG + NQ F Sbjct: 123 SSTYQSTSGTLSITYGTGSMTGILGYDTVQVGGISDTNQIF 163
>PAG_HORSE (Q28389) Pregnancy-associated glycoprotein precursor (EC 3.4.23.-)| (PAG) Length = 388 Score = 100 bits (249), Expect = 3e-21 Identities = 56/137 (40%), Positives = 78/137 (56%) Frame = +3 Query: 144 LRINLNKRSLTHESLAAAKAARQYGALRLKSGNSDSDIVPLVDYLNTQYYGVIGLGTPPQ 323 LR NL ++ + E L + L K +S P+ +YL+ Y G+I +GTPPQ Sbjct: 27 LRENLREKDMLKEYLEKYPFRLTHKLLH-KHADSGVAFEPMRNYLDIAYMGIISVGTPPQ 85 Query: 324 NFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSSRSTTYKADGENCKITYGSGAISGFF 503 F VIFDTGS++LWVPS C S AC H + RS+T+ A G+ K+ YG+G +SGF Sbjct: 86 EFQVIFDTGSADLWVPSIYC-SSPACSNHNTFNPLRSSTFVASGQPIKLIYGTGKMSGFV 144 Query: 504 SNDNVLVGDLVVKNQKF 554 D + + LV +NQ F Sbjct: 145 GYDTIKISSLVDRNQAF 161
>PEPB_CANFA (Q8SQ41) Pepsin B precursor (EC 3.4.23.2)| Length = 390 Score = 100 bits (248), Expect = 4e-21 Identities = 47/109 (43%), Positives = 70/109 (64%) Frame = +3 Query: 261 PLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSSRSTT 440 P +YL++ Y+G I +GTPPQNF ++FDTGSSNLWVPS+ C S AC H ++ SRS+T Sbjct: 65 PFTNYLDSYYFGEISIGTPPQNFLILFDTGSSNLWVPSTYCQ-SQACSNHNRFNPSRSST 123 Query: 441 YKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEATRETSVSF 587 Y++ + + YG G+++ D V V ++V+ NQ F + E + F Sbjct: 124 YQSSEQTYTLAYGFGSLTVLLGYDTVTVQNIVIHNQLFGMSENEPNYPF 172
>CHYM_BOVIN (P00794) Chymosin precursor (EC 3.4.23.4) (Preprorennin)| Length = 381 Score = 99.8 bits (247), Expect = 5e-21 Identities = 57/140 (40%), Positives = 80/140 (57%) Frame = +3 Query: 153 NLNKRSLTHESLAAAKAARQYGALRLKSGNSDSDIVPLVDYLNTQYYGVIGLGTPPQNFT 332 +L K H L +QYG SG + VPL +YL++QY+G I LGTPPQ FT Sbjct: 29 SLRKALKEHGLLEDFLQKQQYGISSKYSGFGEVASVPLTNYLDSQYFGKIYLGTPPQEFT 88 Query: 333 VIFDTGSSNLWVPSSKCYFSIACYLHPKYRSSRSTTYKADGENCKITYGSGAISGFFSND 512 V+FDTGSS+ WVPS C S AC H ++ +S+T++ G+ I YG+G++ G D Sbjct: 89 VLFDTGSSDFWVPSIYCK-SNACKNHQRFDPRKSSTFQNLGKPLSIHYGTGSMQGILGYD 147 Query: 513 NVLVGDLVVKNQKFIEATRE 572 V V ++V Q +T+E Sbjct: 148 TVTVSNIVDIQQTVGLSTQE 167
>PEPA_SORUN (Q9GMY8) Pepsin A precursor (EC 3.4.23.1)| Length = 387 Score = 99.0 bits (245), Expect = 9e-21 Identities = 47/98 (47%), Positives = 64/98 (65%) Frame = +3 Query: 261 PLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSSRSTT 440 PLV+Y++ +Y+G I +GTPPQ FTVIFDTGSSNLWVPS C S AC H ++ +S+T Sbjct: 66 PLVNYMDMEYFGTISIGTPPQEFTVIFDTGSSNLWVPSIYC-SSPACSNHNRFDPQKSST 124 Query: 441 YKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKF 554 +K + I YG+G+++G D V V + NQ F Sbjct: 125 FKPTSQTVSIAYGTGSMTGVLGYDTVQVAGIADTNQIF 162
>PEPC_CAVPO (Q64411) Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C)| Length = 394 Score = 98.2 bits (243), Expect = 2e-20 Identities = 48/117 (41%), Positives = 72/117 (61%) Frame = +3 Query: 204 ARQYGALRLKSGNSDSDIVPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKC 383 AR++ RL S + + Y++ Y+G I LGTPPQ+F V+FDTGSSNLWVPS C Sbjct: 51 ARKFFRNRLAKTGDFSVLYEPMSYMDAAYFGQISLGTPPQSFQVLFDTGSSNLWVPSVYC 110 Query: 384 YFSIACYLHPKYRSSRSTTYKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKF 554 S+AC H ++ S+TY A ++ + YG+G+++G F D + + D+ V Q+F Sbjct: 111 -SSLACTTHTRFNPRDSSTYVATDQSFSLEYGTGSLTGVFGYDTMTIQDIQVPKQEF 166
>PEPA_CANFA (Q9GMY6) Pepsin A precursor (EC 3.4.23.1)| Length = 386 Score = 97.8 bits (242), Expect = 2e-20 Identities = 47/97 (48%), Positives = 62/97 (63%) Frame = +3 Query: 264 LVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSSRSTTY 443 L +Y++ +Y+G IG+GTPPQ FTVIFDTGSSNLWVPS C S AC H ++ S+TY Sbjct: 66 LKNYMDMEYFGTIGIGTPPQEFTVIFDTGSSNLWVPSVYC-SSPACSNHNRFNPQESSTY 124 Query: 444 KADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKF 554 + I YG+G+++G D V VG + NQ F Sbjct: 125 QGTNRPVSIAYGTGSMTGILGYDTVQVGGIADTNQIF 161
>CHYM_CALJA (Q9N2D2) Chymosin precursor (EC 3.4.23.4) (Preprorennin)| Length = 381 Score = 97.1 bits (240), Expect = 3e-20 Identities = 59/155 (38%), Positives = 86/155 (55%), Gaps = 6/155 (3%) Frame = +3 Query: 126 SSRDGLLRINLNK-----RSLTHESLAAAKAARQYGALRLKSGNSDSDIVP-LVDYLNTQ 287 S G++RI L+K R+L L A+ K NS L +YL+ Q Sbjct: 14 SQASGIVRIPLHKGKSLRRALKERGLLEDFLKNHQHAVSRKHSNSREVASEFLTNYLDCQ 73 Query: 288 YYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSSRSTTYKADGENCK 467 Y+G I +GTPPQ FTV+FDTGSS+LWVPS C S+AC H ++ S+S+T++ ++ Sbjct: 74 YFGKIYIGTPPQEFTVVFDTGSSDLWVPSVYCN-SVACQNHHRFDPSKSSTFQNMDKSLS 132 Query: 468 ITYGSGAISGFFSNDNVLVGDLVVKNQKFIEATRE 572 I YG+G++ G D V V +V +Q +T+E Sbjct: 133 IQYGTGSMQGLLGYDTVTVSSIVDPHQTVGLSTQE 167
>PEP2B_GADMO (P56272) Pepsin IIB (EC 3.4.23.-)| Length = 324 Score = 94.0 bits (232), Expect = 3e-19 Identities = 47/98 (47%), Positives = 63/98 (64%) Frame = +3 Query: 279 NTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSSRSTTYKADGE 458 +T+YYGVI +GTPP++F VIFDTGSSNLWV SS C + AC H K++ +S+TY G+ Sbjct: 11 DTEYYGVISIGTPPESFKVIFDTGSSNLWVSSSHC-SAQACSNHNKFKPRQSSTYVETGK 69 Query: 459 NCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEATRE 572 +TYG+G + G D V VG NQ+ E+ E Sbjct: 70 TVDLTYGTGGMRGILGQDTVSVGGGSDPNQELGESQTE 107
>PLM2_PLAFA (P46925) Plasmepsin-2 precursor (EC 3.4.23.39) (Aspartic| hemoglobinase II) (PFAPD) Length = 453 Score = 92.8 bits (229), Expect = 6e-19 Identities = 51/106 (48%), Positives = 65/106 (61%) Frame = +3 Query: 243 SDSDIVPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYR 422 S +D + LVD+ N +YG +G Q FT I DTGS+NLWVPS KC + C Y Sbjct: 125 SSNDNIELVDFQNIMFYGDAEVGDNQQPFTFILDTGSANLWVPSVKC-TTAGCLTKHLYD 183 Query: 423 SSRSTTYKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIE 560 SS+S TY+ DG ++ Y SG +SGFFS D V VG+L + KFIE Sbjct: 184 SSKSRTYEKDGTKVEMNYVSGTVSGFFSKDLVTVGNLSLP-YKFIE 228
>PEPAF_RABIT (P27823) Pepsin F precursor (EC 3.4.23.1)| Length = 388 Score = 92.4 bits (228), Expect = 8e-19 Identities = 50/112 (44%), Positives = 65/112 (58%), Gaps = 2/112 (1%) Frame = +3 Query: 225 RLKSGNSDSDIV--PLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIA 398 +L SG D D+ PL +YL+ Y G+I +GTPPQ F V+ DTGS++LWVPS C S A Sbjct: 51 KLLSGQQDPDVSFEPLRNYLDLAYIGIISIGTPPQEFKVVLDTGSADLWVPSIYC-SSPA 109 Query: 399 CYLHPKYRSSRSTTYKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKF 554 C H + S+T+ G I YGSG +SGF + D V + LV Q F Sbjct: 110 CGKHNTFNPLLSSTFLVSGRPINIVYGSGRMSGFLAYDTVQIAGLVDVAQAF 161
>CARP1_RHINI (P10602) Rhizopuspepsin-1 precursor (EC 3.4.23.21) (Aspartate| protease) Length = 389 Score = 91.7 bits (226), Expect = 1e-18 Identities = 61/175 (34%), Positives = 92/175 (52%), Gaps = 7/175 (4%) Frame = +3 Query: 75 LVTTCLWAISCAVPHHASSRDGLLRINLNKRSLTHESLAAA--KAARQYGALRLKSGNSD 248 L+++C+ + + A+ + I L K + S A KA +Y ++ SG Sbjct: 5 LISSCVALAAMTLAVEAAPNGKKINIPLAKNNSYKPSAKNALNKALAKYNRRKVGSGGIT 64 Query: 249 SDI---VPLVDYLN-TQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPK 416 ++ VP+VDY N +YYG + +GTP + FDTGSS++W S+ C S H K Sbjct: 65 TEASGSVPMVDYENDVEYYGEVTVGTPGIKLKLDFDTGSSDMWFASTLC--SSCSNSHTK 122 Query: 417 YRSSRSTTYKADGENCKITYGSG-AISGFFSNDNVLVGDLVVKNQKFIEATRETS 578 Y +S+TY ADG I+YG G + SG + DNV +G L++K Q A RE+S Sbjct: 123 YDPKKSSTYAADGRTWSISYGDGSSASGILATDNVNLGGLLIKKQTIELAKRESS 177
>PLM1_PLAFA (P39898) Plasmepsin-1 precursor (EC 3.4.23.38) (Aspartic| hemoglobinase I) (PfAPG) Length = 452 Score = 90.5 bits (223), Expect = 3e-18 Identities = 51/110 (46%), Positives = 65/110 (59%) Frame = +3 Query: 237 GNSDSDIVPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPK 416 GN+ D V L D N YYG +G Q F IFDTGS+NLWVPS++C +I C Sbjct: 123 GNA-GDSVTLNDVANVMYYGEAQIGDNKQKFAFIFDTGSANLWVPSAQCN-TIGCKTKNL 180 Query: 417 YRSSRSTTYKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEAT 566 Y S++S TY+ DG ++ Y SG +SGFFS D V + +L KFIE T Sbjct: 181 YDSNKSKTYEKDGTKVEMNYVSGTVSGFFSKDIVTIANLSFP-YKFIEVT 229
>PLM1_PLAF7 (Q7KQM4) Plasmepsin-1 precursor (EC 3.4.23.38) (Aspartic| hemoglobinase I) (PfAPG) Length = 452 Score = 90.5 bits (223), Expect = 3e-18 Identities = 51/110 (46%), Positives = 65/110 (59%) Frame = +3 Query: 237 GNSDSDIVPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPK 416 GN+ D V L D N YYG +G Q F IFDTGS+NLWVPS++C +I C Sbjct: 123 GNA-GDSVTLNDVANVMYYGEAQIGDNKQKFAFIFDTGSANLWVPSAQCN-TIGCKTKNL 180 Query: 417 YRSSRSTTYKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEAT 566 Y S++S TY+ DG ++ Y SG +SGFFS D V + +L KFIE T Sbjct: 181 YDSNKSKTYEKDGTKVEMNYVSGTVSGFFSKDIVTIANLSFP-YKFIEVT 229
>CARP_RHICH (P06026) Rhizopuspepsin precursor (EC 3.4.23.21)| Length = 393 Score = 87.8 bits (216), Expect = 2e-17 Identities = 60/178 (33%), Positives = 94/178 (52%), Gaps = 10/178 (5%) Frame = +3 Query: 75 LVTTCLWAISCAVPHHASSRDGLLRINLNKRSLTHESL--AAAKAARQYGALRLKSGNS- 245 L+++C+ + AV A+ + + I L K S A KA +Y ++ + Sbjct: 5 LISSCIAIAALAVAVDAAPGEKKISIPLAKNPNYKPSAKNAIQKAIAKYNKHKINTSTGG 64 Query: 246 ---DSDI--VPLVDYLN-TQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYL 407 D+ + VP+ DY N +YYG + +GTP + F + FDTGSS+LW+ S+ C + Sbjct: 65 IVPDAGVGTVPMTDYGNDVEYYGQVTIGTPGKKFNLDFDTGSSDLWIASTLC--TNCGSR 122 Query: 408 HPKYRSSRSTTYKADGENCKITYGSG-AISGFFSNDNVLVGDLVVKNQKFIEATRETS 578 KY +S+TY+ADG I+YG G + SG + DNV +G L++K Q A RE + Sbjct: 123 QTKYDPKQSSTYQADGRTWSISYGDGSSASGILAKDNVNLGGLLIKGQTIELAKREAA 180
>PAG1_BOVIN (Q29432) Pregnancy-associated glycoprotein 1 precursor (EC| 3.4.23.-) (PAG 1) (Pregnancy-specific protein B) (PSP-B) Length = 380 Score = 87.8 bits (216), Expect = 2e-17 Identities = 46/114 (40%), Positives = 67/114 (58%) Frame = +3 Query: 213 YGALRLKSGNSDSDIVPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFS 392 Y ++ S+ PL + + Y G I +GTPPQ F V+FDT SS+LWVPS C S Sbjct: 46 YSLSQISFRGSNLTTHPLRNIKDLVYMGNITIGTPPQEFQVVFDTASSDLWVPSDFC-TS 104 Query: 393 IACYLHPKYRSSRSTTYKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKF 554 AC H ++R +S+T++ + +ITYGSG + G +D V +G+LV +Q F Sbjct: 105 PACSTHVRFRHLQSSTFRLTNKTFRITYGSGRMKGVVVHDTVRIGNLVSTDQPF 158
>PAG1_PIG (Q29078) Pregnancy-associated glycoprotein 1 precursor (EC| 3.4.23.-) (PAG 1) Length = 389 Score = 84.0 bits (206), Expect = 3e-16 Identities = 42/97 (43%), Positives = 60/97 (61%) Frame = +3 Query: 264 LVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSSRSTTY 443 L +YL+ Y G I +GTPPQ F+VIFDT SS+LWVPS++C+ S AC H + + S+T+ Sbjct: 68 LWNYLDMVYVGNITIGTPPQLFSVIFDTASSDLWVPSNQCH-SRACVTHRSFNPTLSSTF 126 Query: 444 KADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKF 554 ++ K+ SG +SG D V +G +NQ F Sbjct: 127 QSSNRTVKLAPHSGLVSGLLGYDTVQIGRFKSENQAF 163
>PAG1_SHEEP (Q28755) Pregnancy-associated glycoprotein 1 precursor (EC| 3.4.23.-) (PAG 1) Length = 382 Score = 82.8 bits (203), Expect = 7e-16 Identities = 43/106 (40%), Positives = 64/106 (60%), Gaps = 2/106 (1%) Frame = +3 Query: 243 SDSDIVPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSI--ACYLHPK 416 S+ I PL + ++ Y G I +GTPPQ F V+FDTGSS+L VPS C C K Sbjct: 56 SNLTIHPLRNIMDMLYVGNITIGTPPQEFQVVFDTGSSDLLVPSINCLSPTKRPCSKQDK 115 Query: 417 YRSSRSTTYKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKF 554 ++ +S+T++ + +I +GSG + GF ++D V +GDLV +Q F Sbjct: 116 FKHHQSSTFRFTNDTFRIYFGSGTMRGFVAHDTVRIGDLVSTDQPF 161
>CARP_RHIPU (P09177) Mucorpepsin precursor (EC 3.4.23.23) (Mucor rennin)| Length = 427 Score = 81.6 bits (200), Expect = 1e-15 Identities = 51/163 (31%), Positives = 84/163 (51%), Gaps = 4/163 (2%) Frame = +3 Query: 72 LLVTTCLWAISCAVP--HHASSRDGLLRINLNKRSLTH-ESLAAAKAARQYGALR-LKSG 239 +L+T +A++ A P + + D LL + L + + ++ +AA + G ++ G Sbjct: 10 ILLTAASFALTSARPVSKQSDADDKLLALPLTSVNRKYSQTKHGQQAAEKLGGIKAFAEG 69 Query: 240 NSDSDIVPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKY 419 + D L D+ +Y + +GTP Q+F ++FDTGSS+ WVP C S C + Sbjct: 70 DGSVDTPGLYDFDLEEYAIPVSIGTPGQDFYLLFDTGSSDTWVPHKGCDNSEGCVGKRFF 129 Query: 420 RSSRSTTYKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQ 548 S S+T+K N ITYG+G +G + D++ VG VK Q Sbjct: 130 DPSSSSTFKETDYNLNITYGTGGANGIYFRDSITVGGATVKQQ 172
>CARP_SYNRA (P81214) Syncephapepsin precursor (EC 3.4.23.-)| Length = 395 Score = 81.3 bits (199), Expect = 2e-15 Identities = 59/182 (32%), Positives = 91/182 (50%), Gaps = 11/182 (6%) Frame = +3 Query: 66 LLLLVTTCLWAISCAVPHHASSRDGLLRINLNKRSLTHESLAAAKAARQY---------G 218 L LL T L IS A P ++ N + + A +A ++Y G Sbjct: 5 LALLATVALATISQAAPVEKQVAGKPFQLVKNPHYQANATRAIFRAEKKYARHTAIPEQG 64 Query: 219 ALRLKSGNSDSDIVPLVDY-LNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSI 395 +KS S + VP+ D + +YY + +GTP Q+ + FDTGSS+LW S+ C Sbjct: 65 KTIVKSAASGTGSVPMTDVDYDVEYYATVSVGTPAQSIKLDFDTGSSDLWFSSTLC---T 121 Query: 396 ACYLHPKYRSSRSTTYKADGENCKITYGSG-AISGFFSNDNVLVGDLVVKNQKFIEATRE 572 +C + ++S+TYK G++ +I+YG G + SG + DNV +G L + Q ATRE Sbjct: 122 SCG-SKSFDPTKSSTYKKVGKSWQISYGDGSSASGITATDNVELGGLKITGQTIELATRE 180 Query: 573 TS 578 +S Sbjct: 181 SS 182
>CARP3_RHINI (Q03699) Rhizopuspepsin-3 precursor (EC 3.4.23.21) (Aspartate| protease) Length = 391 Score = 80.9 bits (198), Expect = 3e-15 Identities = 59/177 (33%), Positives = 88/177 (49%), Gaps = 9/177 (5%) Frame = +3 Query: 75 LVTTC--LWAISCAVPHHASSRDGLLRINLNKRSLTHESLAAAKAARQYGALR-LKSGNS 245 L+++C L ++ ++ S + + + NK + A KA +Y R + S NS Sbjct: 5 LISSCVTLALMTLSIEAAPSGKKVNIPLTKNKDYKPNAKNAIQKAIAKYHRHRSVSSSNS 64 Query: 246 DSD----IVPLVDYLNT-QYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLH 410 S VP+ DY N +YYG + +GTP + FDTGSS+LW SS C + Sbjct: 65 TSTDGIGYVPVTDYYNDIEYYGEVTVGTPGVTLKLDFDTGSSDLWFASSLC--TNCGSSQ 122 Query: 411 PKYRSSRSTTYKADGENCKITYGSG-AISGFFSNDNVLVGDLVVKNQKFIEATRETS 578 KY + S+TY DG I+YG G + SG D V++G L +++Q A RE S Sbjct: 123 TKYNPNESSTYARDGRTWSISYGDGSSASGILGTDTVILGGLTIRHQTIELARREAS 179
>CARP_RHIMI (P00799) Mucorpepsin precursor (EC 3.4.23.23) (Mucor rennin)| Length = 430 Score = 80.1 bits (196), Expect = 4e-15 Identities = 50/166 (30%), Positives = 81/166 (48%), Gaps = 7/166 (4%) Frame = +3 Query: 72 LLVTTCLWAISCAVP--HHASSRDGLLRINLNK--RSLTHESLAAAKAARQYGALRLKS- 236 +L+T +++ A P + S+D LL + L R + + A + L+ S Sbjct: 10 ILLTAASLSLTTARPVSKQSESKDKLLALPLTSVSRKFSQTKFGQQQLAEKLAGLKPFSE 69 Query: 237 --GNSDSDIVPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLH 410 + D D+ +Y + +GTP Q+F ++FDTGSS+ WVP C S C Sbjct: 70 AAADGSVDTPGYYDFDLEEYAIPVSIGTPGQDFLLLFDTGSSDTWVPHKGCTKSEGCVGS 129 Query: 411 PKYRSSRSTTYKADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQ 548 + S S+T+KA N ITYG+G +G + D++ +GD+ V Q Sbjct: 130 RFFDPSASSTFKATNYNLNITYGTGGANGLYFEDSIAIGDITVTKQ 175
>CARP2_RHINI (P43231) Rhizopuspepsin-2 precursor (EC 3.4.23.21) (Aspartate| protease) Length = 391 Score = 79.3 bits (194), Expect = 7e-15 Identities = 58/179 (32%), Positives = 85/179 (47%), Gaps = 9/179 (5%) Frame = +3 Query: 69 LLLVTTCLWAISCAVPHHASSRDGLLRINLNKRSLTHESL--AAAKAARQYGALRLKSGN 242 L L+++C+ A+ A+ L I L K + S A KA +Y R S + Sbjct: 3 LTLISSCVALAFMALATEAAPSGKKLSIPLTKNTNYKPSAKNAIQKALAKYHRFRTTSSS 62 Query: 243 SDSDI-----VPLVDYLNT-QYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACY 404 + + VP+ DY N +YYG + +GTP + FDTGSS+LW S+ C + Sbjct: 63 NSTSTEGTGSVPVTDYYNDIEYYGKVTVGTPGVTLKLDFDTGSSDLWFASTLC--TNCGS 120 Query: 405 LHPKYRSSRSTTYKADGENCKITYGSG-AISGFFSNDNVLVGDLVVKNQKFIEATRETS 578 KY ++S+TY DG I+YG G + SG D V +G L + Q A RE + Sbjct: 121 SQTKYNPNQSSTYAKDGRTWSISYGDGSSASGILGTDTVTLGGLKITKQTIELAKREAT 179
>CARP5_RHINI (P43232) Rhizopuspepsin-5 precursor (EC 3.4.23.21) (Aspartate| protease) Length = 392 Score = 79.3 bits (194), Expect = 7e-15 Identities = 58/178 (32%), Positives = 85/178 (47%), Gaps = 10/178 (5%) Frame = +3 Query: 75 LVTTCLWAISCAVPHHASSRDGLLRINL--NKRSLTHESLAAAKAARQYGALRLKSGNSD 248 L+++C+ + A+ + I L NK + A K +Y R S +S+ Sbjct: 5 LISSCVALAVLVLSTEAAPNGKKVNIPLTKNKDYKPNAKNAIQKVLAKYHRHRSTSSSSN 64 Query: 249 SDI------VPLVDYLNT-QYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYL 407 S VP+ DY N +Y+G + +GTP + FDTGSS+LW SS C + Y Sbjct: 65 STSTDGIGRVPVTDYYNDIEYFGQVKVGTPGVTLKLDFDTGSSDLWFASSLC--TNCGYS 122 Query: 408 HPKYRSSRSTTYKADGENCKITYGSG-AISGFFSNDNVLVGDLVVKNQKFIEATRETS 578 KY ++S TY DG I+YG G + SG D V++G L ++ Q A RE S Sbjct: 123 QTKYNPNQSRTYAKDGRAWSISYGDGSSASGILGTDTVVLGGLTIQRQTIELARREAS 180
>CARP4_RHINI (Q03700) Rhizopuspepsin-4 precursor (EC 3.4.23.21) (Aspartate| protease) Length = 398 Score = 76.6 bits (187), Expect = 5e-14 Identities = 59/183 (32%), Positives = 86/183 (46%), Gaps = 15/183 (8%) Frame = +3 Query: 75 LVTTCLWAISCAVPHHASSRDGLLRINLNKRS--LTHESLAAAKAARQYGALRLKSGNSD 248 L+++C+ A+ A+ + + L+K + + A KA +Y R S +S Sbjct: 5 LISSCVALACMALAVEAAPSGKKINVPLSKNANYKPNAKRAIEKANAKYARFRSSSSSSS 64 Query: 249 SDI-----------VPLVDYLNT-QYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFS 392 S VP+ D N +YYG + +GTP + FDTGSS+LW S+ C + Sbjct: 65 SSSCGSAGTESSGSVPVTDDGNDIEYYGEVTVGTPGIKLKLDFDTGSSDLWFASTLC--T 122 Query: 393 IACYLHPKYRSSRSTTYKADGENCKITYGSG-AISGFFSNDNVLVGDLVVKNQKFIEATR 569 KY S+S+TY DG I+YG G + SG D V +G L +KNQ A R Sbjct: 123 NCGSSQTKYDPSQSSTYAKDGRTWSISYGDGSSASGILGKDTVNLGGLKIKNQIIELAKR 182 Query: 570 ETS 578 E S Sbjct: 183 EAS 185
>CARP1_CANPA (P32951) Candidapepsin-1 precursor (EC 3.4.23.24) (Aspartate| protease 1) (ACP 1) Length = 402 Score = 59.3 bits (142), Expect = 8e-09 Identities = 53/183 (28%), Positives = 88/183 (48%), Gaps = 6/183 (3%) Frame = +3 Query: 51 TMGQRLLLLVTTCLWAISCAVPHHASSRD---GLLRINLNKRSLTHESLAAAKAARQYGA 221 T+ +++LL + L+A A+P A+ RD G + ++ + + + L +A Sbjct: 6 TLTRQVLLTIALALFAQGAAIPEEAAKRDDNPGFVALDFD---VLRKPLNLTEAL----- 57 Query: 222 LRLKSGNSDSDIVPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSS--KCYFSI 395 LR K DS + L++ Y + +G+ Q TVI DTGSS+ WV S +C + Sbjct: 58 LREKR---DSISLSLINE-GPSYASKVSVGSNKQQQTVIIDTGSSDFWVVDSNAQCGKGV 113 Query: 396 ACYLHPKYRSSRSTTYKADGENCKITYGSGAIS-GFFSNDNVLVGDLVVKNQKFIEATRE 572 C + S S++YK G I YG G+ S G + D V + + + Q+ + T + Sbjct: 114 DCKSSGTFTPSSSSSYKNLGAAFTIRYGDGSTSQGTWGKDTVTINGVSITGQQIADVT-Q 172 Query: 573 TSV 581 TSV Sbjct: 173 TSV 175
>CARP_SACFI (P22929) Acid protease precursor (EC 3.4.23.-)| Length = 390 Score = 58.9 bits (141), Expect = 1e-08 Identities = 45/167 (26%), Positives = 79/167 (47%), Gaps = 1/167 (0%) Frame = +3 Query: 75 LVTTCLWAISCAVPHHASSRDGLLRINLNKRSLTHESLAAAKAARQYGALRLKSGNSDSD 254 L+ + L ++S A P + L ++ + S +++ A + G R SD+ Sbjct: 7 LLLSVLASLSFAAPVEKREKTLTLDFDVKRISSKAKNVTVASSP---GFRRNLRAASDAG 63 Query: 255 IVPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSSRS 434 + ++ + Y I +GTP Q V DTGSS+LWVP L+ Y ++S Sbjct: 64 VTISLENEYSFYLTTIEIGTPGQKLQVDVDTGSSDLWVPGQG-----TSSLYGTYDHTKS 118 Query: 435 TTYKADGENCKITYGSGAIS-GFFSNDNVLVGDLVVKNQKFIEATRE 572 T+YK D I+YG G+ + G ++ + V +G + +F +AT + Sbjct: 119 TSYKKDRSGFSISYGDGSSARGDWAQETVSIGGASITGLEFGDATSQ 165
>CARP_IRPLA (P17576) Polyporopepsin (EC 3.4.23.29) (Aspartic proteinase)| Length = 340 Score = 57.8 bits (138), Expect = 2e-08 Identities = 32/104 (30%), Positives = 53/104 (50%) Frame = +3 Query: 264 LVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSSRSTTY 443 LVDY+ +G+G+P ++++ DTGSSN W+ + K Y +++T Sbjct: 11 LVDYVVN-----VGVGSPATTYSLLVDTGSSNTWLGADKSYV-------------KTSTS 52 Query: 444 KADGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEATRET 575 A + +TYGSG+ SG D V +G L + Q A+R++ Sbjct: 53 SATSDKVSVTYGSGSFSGTEYTDTVTLGSLTIPKQSIGVASRDS 96
>CARP_CRYPA (P11838) Endothiapepsin precursor (EC 3.4.23.22) (Aspartate| protease) Length = 419 Score = 57.8 bits (138), Expect = 2e-08 Identities = 43/109 (39%), Positives = 57/109 (52%), Gaps = 2/109 (1%) Frame = +3 Query: 267 VDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSSRSTTYK 446 +D L+ Y + +GTP Q + FDTGSS+LWV SS+ S Y S+STT K Sbjct: 99 IDSLDDAYITPVQIGTPAQTLNLDFDTGSSDLWVFSSETTAS-EVDGQTIYTPSKSTTAK 157 Query: 447 -ADGENCKITYGSG-AISGFFSNDNVLVGDLVVKNQKFIEATRETSVSF 587 G I+YG G + SG D V VG L V Q +E+ ++ S SF Sbjct: 158 LLSGATWSISYGDGSSSSGDVYTDTVSVGGLTVTGQA-VESAKKVSSSF 205
>YPS3_YEAST (Q12303) Aspartic proteinase yapsin-3 precursor (EC 3.4.23.-)| Length = 508 Score = 52.4 bits (124), Expect = 1e-06 Identities = 33/103 (32%), Positives = 53/103 (51%), Gaps = 6/103 (5%) Frame = +3 Query: 288 YYGV-IGLGTPPQNFTVIFDTGSSNLWVP---SSKCYFSIACYLHPKYRSSRSTTYKADG 455 +Y V + +GTP QN TV+ DTGS++LWVP + C + C + + ++S+T+KA+ Sbjct: 62 FYSVELAIGTPSQNLTVLLDTGSADLWVPGKGNPYCGSVMDCDQYGVFDKTKSSTFKANK 121 Query: 456 EN-CKITYGSGAIS-GFFSNDNVLVGDLVVKNQKFIEATRETS 578 + YG G + G F D + +L + F A S Sbjct: 122 SSPFYAAYGDGTYAEGAFGQDKLKYNELDLSGLSFAVANESNS 164
>CARP_PODAN (O13340) Podosporapepsin precursor (EC 3.4.23.-)| Length = 425 Score = 51.6 bits (122), Expect = 2e-06 Identities = 41/120 (34%), Positives = 60/120 (50%), Gaps = 2/120 (1%) Frame = +3 Query: 225 RLKSGNSDSDIVPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACY 404 R+K + +P ++ ++ Y + +GTPPQ + DTGSS+LWV SS S Sbjct: 88 RIKRDTGSAAAIP-INEVDIAYVTPVTIGTPPQTLMLDLDTGSSDLWVFSSLTP-SNQVR 145 Query: 405 LHPKYRSSRSTTYK-ADGENCKITYGSGAIS-GFFSNDNVLVGDLVVKNQKFIEATRETS 578 Y ++S+T K G I YG G+ S G DN +G L VK+Q ++A E S Sbjct: 146 GQEIYSPTKSSTSKLLSGHTWSIRYGDGSGSRGTVYTDNFTIGGLEVKSQA-VQAALEVS 204
>BACE2_HUMAN (Q9Y5Z0) Beta-secretase 2 precursor (EC 3.4.23.45) (Beta-site| APP-cleaving enzyme 2) (Aspartyl protease 1) (Asp 1) (ASP1) (Membrane-associated aspartic protease 1) (Memapsin-1) (Down region aspartic protease) Length = 518 Score = 49.7 bits (117), Expect = 6e-06 Identities = 26/79 (32%), Positives = 42/79 (53%) Frame = +3 Query: 288 YYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSSRSTTYKADGENCK 467 YY + +GTPPQ ++ DTGSSN V + Y+ + + RS+TY++ G + Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTP-----HSYIDTYFDTERSSTYRSKGFDVT 146 Query: 468 ITYGSGAISGFFSNDNVLV 524 + Y G+ +GF D V + Sbjct: 147 VKYTQGSWTGFVGEDLVTI 165
>CARP8_CANAL (O42778) Candidapepsin-8 precursor (EC 3.4.23.24) (Aspartate| protease 8) (ACP 8) (Secreted aspartic protease 8) Length = 405 Score = 48.9 bits (115), Expect = 1e-05 Identities = 34/102 (33%), Positives = 47/102 (46%), Gaps = 9/102 (8%) Frame = +3 Query: 288 YYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIA--------CYLHPKYRSSRSTTY 443 Y I +G+ Q TVI DTGSS+LWV S + C Y+ S STT Sbjct: 89 YAATITVGSNKQQQTVIVDTGSSDLWVVDSAAVCQVTYPGQSPTFCKQDGTYKPSSSTTS 148 Query: 444 KADGENCKITYGSGAIS-GFFSNDNVLVGDLVVKNQKFIEAT 566 + G+ I Y G+ S G D + +G + NQ+F + T Sbjct: 149 QNLGKAFSIRYEDGSSSQGTVYKDTIGLGGASITNQQFADVT 190
>PEPF_ASPFU (P41748) Aspergillopepsin F precursor (EC 3.4.23.18)| (Aspergillopepsin I) Length = 395 Score = 47.8 bits (112), Expect = 2e-05 Identities = 48/174 (27%), Positives = 81/174 (46%), Gaps = 4/174 (2%) Frame = +3 Query: 78 VTTCLWAISCAVPHHASSRDGLLRINLNKRSLTHESLAAAKAARQYGAL---RLKSGNSD 248 ++T + A+ P + + + R NK+++ ++ A A +YG +K+ S Sbjct: 14 LSTIVSAVPVVQPRKGFTINQVARPVTNKKTVNLPAVYA-NALTKYGGTVPDSVKAAASS 72 Query: 249 SDIVPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSS 428 V + +++Y + +G N FDTGS++LWV SS+ S + H Y+ S Sbjct: 73 GSAVTTPEQYDSEYLTPVKVGGTTLNLD--FDTGSADLWVFSSELSASQSSG-HAIYKPS 129 Query: 429 RSTTYKADGENCKITYGSG-AISGFFSNDNVLVGDLVVKNQKFIEATRETSVSF 587 + K +G KI YG G + SG D V VG + ++Q +EA S F Sbjct: 130 -ANAQKLNGYTWKIQYGDGSSASGDVYKDTVTVGGVTAQSQA-VEAASHISSQF 181
>CARP3_CANAL (P43092) Candidapepsin-3 precursor (EC 3.4.23.24) (Aspartate| protease 3) (ACP 3) (Secreted aspartic protease 3) Length = 398 Score = 47.0 bits (110), Expect = 4e-05 Identities = 37/115 (32%), Positives = 52/115 (45%), Gaps = 10/115 (8%) Frame = +3 Query: 267 VDYLNTQ--YYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIA-------CYLHPKY 419 V +N Q Y I +G+ Q TV+ DTGSS+LWVP S+ C Y Sbjct: 63 VKLINEQVSYASDITVGSNKQKLTVVIDTGSSDLWVPDSQVSCQAGQGQDPNFCKNEGTY 122 Query: 420 RSSRSTTYKADGENCKITYGSGAIS-GFFSNDNVLVGDLVVKNQKFIEATRETSV 581 S S++ + I YG G S G + D + G + + Q+F + T TSV Sbjct: 123 SPSSSSSSQNLNSPFSIEYGDGTTSQGTWYKDTIGFGGISITKQQFADVT-STSV 176
>MKC7_YEAST (P53379) Aspartic proteinase MKC7 precursor (EC 3.4.23.41) (Yapsin| 2) Length = 596 Score = 46.6 bits (109), Expect = 5e-05 Identities = 24/54 (44%), Positives = 34/54 (62%) Frame = +3 Query: 216 GALRLKSGNSDSDIVPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSS 377 G RL + + D ++V L + N+ Y + +GTPPQ TV+ DTGSS+LWV S Sbjct: 58 GRTRLMTRDDDYELVELTNQ-NSFYSVELDIGTPPQKVTVLVDTGSSDLWVTGS 110
>CARP6_CANAL (P43095) Candidapepsin-6 precursor (EC 3.4.23.24) (Aspartate| protease 6) (ACP 6) (Secreted aspartic protease 6) Length = 418 Score = 46.2 bits (108), Expect = 7e-05 Identities = 33/98 (33%), Positives = 45/98 (45%), Gaps = 9/98 (9%) Frame = +3 Query: 288 YYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCY--------FSIACYLHPKYRSSRSTTY 443 Y I +G+ Q +VI DTGSS+LW+P SK C + Y + S+T Sbjct: 90 YSADITVGSNNQKLSVIVDTGSSDLWIPDSKAICIPKWRGDCGDFCKNNGSYSPAASSTS 149 Query: 444 KADGENCKITYGSGAIS-GFFSNDNVLVGDLVVKNQKF 554 K +I Y G+ + G D V +G VKNQ F Sbjct: 150 KNLNTRFEIKYADGSYAKGNLYQDTVGIGGASVKNQLF 187
>CARP2_CANPA (P32950) Candidapepsin-2 precursor (EC 3.4.23.24) (Aspartate| protease 2) (ACP 2) Length = 412 Score = 46.2 bits (108), Expect = 7e-05 Identities = 48/179 (26%), Positives = 77/179 (43%), Gaps = 4/179 (2%) Frame = +3 Query: 60 QRLLLLVTTCLWAISCAVPHHASSRDGLLRINLNKRSLTHESLAAAKAARQYGALRLKSG 239 + +LL + L+A A+P A D N + + K L Sbjct: 9 KNVLLAIAFALFAQGAAIPDPAKRDD-------NPGFVALDFEVTRKPLDVNATSELSKR 61 Query: 240 NSDSDIVPLVDYLNTQYYGV-IGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIA-CYLHP 413 +S S PL Y YG+ + +G+ Q V+ DTGSS+ WV S C + Sbjct: 62 SSPSS--PL--YFEGPSYGIRVSVGSNKQEQQVVLDTGSSDFWVVDSSASCQKGNCKQYG 117 Query: 414 KYRSSRSTTYKADGENCK-ITYGSGAIS-GFFSNDNVLVGDLVVKNQKFIEATRETSVS 584 + ST++K+ G + + I YG + S G + D + +G + NQ+F + T TSV+ Sbjct: 118 TFDPHSSTSFKSLGSSFRSIGYGDKSSSIGTWGQDTIYLGGTSITNQRFADVT-STSVN 175
>BAR1_YEAST (P12630) Barrierpepsin precursor (EC 3.4.23.35) (Extracellular| "barrier" protein) (BAR proteinase) Length = 587 Score = 45.8 bits (107), Expect = 9e-05 Identities = 34/122 (27%), Positives = 52/122 (42%), Gaps = 25/122 (20%) Frame = +3 Query: 264 LVDYLNTQYYGV-IGLGTPPQNFTVIFDTGSSNLWVPSSKCYF----------------- 389 L+ + YY + +GTP Q+ TV+FDTGS++ WV S F Sbjct: 36 LLQHEEEMYYATTLDIGTPSQSLTVLFDTGSADFWVMDSSNPFCLPNSNTSSYSNATYNG 95 Query: 390 -----SIACYLHPKYRSSRSTTYK-ADGENCKITYGSGAIS-GFFSNDNVLVGDLVVKNQ 548 SI C Y RS+TY+ + ITY G + G + + V + + + N Sbjct: 96 EEVKPSIDCRSMSTYNEHRSSTYQYLENGRFYITYADGTFADGSWGTETVSINGIDIPNI 155 Query: 549 KF 554 +F Sbjct: 156 QF 157
>CARP7_CANAL (P43096) Candidapepsin-7 precursor (EC 3.4.23.24) (Aspartate| protease 7) (ACP 7) (Secreted aspartic protease 7) Length = 588 Score = 45.8 bits (107), Expect = 9e-05 Identities = 34/112 (30%), Positives = 53/112 (47%), Gaps = 8/112 (7%) Frame = +3 Query: 267 VDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPS---SKCYF---SIACYLHPKYRSS 428 +D T Y + +G+P Q V+ DTGSS+LW S S+C SI C + + S Sbjct: 219 LDNTQTLYTATLKVGSPAQEVQVMIDTGSSDLWFISSGNSQCKVNGGSIDCDKYGVFDKS 278 Query: 429 RSTTYKADGENCKITYGSG-AISGFFSNDNVLVGD-LVVKNQKFIEATRETS 578 +S+++ + + I+Y G SG DN+ D ++N F TS Sbjct: 279 KSSSWHDNKTDYSISYYDGDKASGTMGQDNITFADGFSIENANFAVIDNTTS 330
>CARP_CANTR (Q00663) Candidapepsin precursor (EC 3.4.23.24) (Aspartate| protease) (ACP) Length = 394 Score = 44.7 bits (104), Expect = 2e-04 Identities = 34/115 (29%), Positives = 54/115 (46%), Gaps = 9/115 (7%) Frame = +3 Query: 249 SDIVPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWV--PSSKCYFSIA------CY 404 SD+ + Y I +G+ Q TV+ DTGSS+LWV ++C + + C Sbjct: 61 SDVPTTLINEGPSYAADIVVGSNQQKQTVVIDTGSSDLWVVDTDAECQVTYSGQTNNFCK 120 Query: 405 LHPKYRSSRSTTYKADGENCKITYGSGAIS-GFFSNDNVLVGDLVVKNQKFIEAT 566 + S S++ + ++ I YG S G F D V G + +KNQ+F + T Sbjct: 121 QEGTFDPSSSSSAQNLNQDFSIEYGDLTSSQGSFYKDTVGFGGISIKNQQFADVT 175
>CARP1_CANAL (P28872) Candidapepsin-1 precursor (EC 3.4.23.24) (Aspartate| protease 1) (ACP 1) (Secreted aspartic protease 1) Length = 391 Score = 43.9 bits (102), Expect = 3e-04 Identities = 36/110 (32%), Positives = 48/110 (43%), Gaps = 13/110 (11%) Frame = +3 Query: 279 NTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIAC----------YLHPK--YR 422 + Y I +G+ Q F VI DTGSS+LWVP + S+ C + K Y Sbjct: 61 HVSYAADITIGSNKQKFNVIVDTGSSDLWVPDA----SVTCDKPRPGQSADFCKGKGIYT 116 Query: 423 SSRSTTYKADGENCKITYGSGAIS-GFFSNDNVLVGDLVVKNQKFIEATR 569 STT + G I YG G+ S G D V G + Q F + T+ Sbjct: 117 PKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITK 166
>CARP4_CANAL (P43093) Candidapepsin-4 precursor (EC 3.4.23.24) (Aspartate| protease 4) (ACP 4) (Secreted aspartic protease 4) Length = 417 Score = 43.9 bits (102), Expect = 3e-04 Identities = 34/106 (32%), Positives = 49/106 (46%), Gaps = 9/106 (8%) Frame = +3 Query: 288 YYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYF--------SIACYLHPKYRSSRSTTY 443 Y I +G+ Q +VI DTGSS+LWVP S C + Y + S+T Sbjct: 89 YSADITIGSNNQKLSVIVDTGSSDLWVPDSNAVCIPKWPGDRGDFCKNNGSYSPAASSTS 148 Query: 444 KADGENCKITYGSGAIS-GFFSNDNVLVGDLVVKNQKFIEATRETS 578 K +I Y G+++ G D V +G + V++Q F R TS Sbjct: 149 KNLNTPFEIKYADGSVAQGNLYQDTVGIGGVSVRDQLFAN-VRSTS 193
>NEP2_NEPGR (Q766C2) Aspartic proteinase nepenthesin-2 precursor (EC 3.4.23.-)| (Nepenthesin-II) Length = 438 Score = 43.5 bits (101), Expect = 5e-04 Identities = 42/147 (28%), Positives = 65/147 (44%), Gaps = 24/147 (16%) Frame = +3 Query: 117 HHASSRDGL-LRINLNK----RSLTHESLAAAKAARQYGALRLKSGN----SDSDIVPLV 269 HH R LR++L + ++LT L K A + G R++S N S S I V Sbjct: 32 HHGQKRPQPGLRVDLEQVDSGKNLTKYELI--KRAIKRGERRMRSINAMLQSSSGIETPV 89 Query: 270 DYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWV---PSSKCYFSIACYLHPKYRSSRST- 437 + +Y + +GTP +F+ I DTGS +W P ++C+ +P+ SS ST Sbjct: 90 YAGDGEYLMNVAIGTPDSSFSAIMDTGSDLIWTQCEPCTQCFSQPTPIFNPQDSSSFSTL 149 Query: 438 -----------TYKADGENCKITYGSG 485 + + C+ TYG G Sbjct: 150 PCESQYCQDLPSETCNNNECQYTYGYG 176
>CARP5_CANAL (P43094) Candidapepsin-5 precursor (EC 3.4.23.24) (Aspartate| protease 5) (ACP 5) (Secreted aspartic protease 5) Length = 418 Score = 42.4 bits (98), Expect = 0.001 Identities = 32/104 (30%), Positives = 47/104 (45%), Gaps = 15/104 (14%) Frame = +3 Query: 288 YYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRSSRSTTYKADGE--- 458 Y I +G+ Q VI DTGSS+LW+P S ++ C PK+R + K+ G Sbjct: 90 YTADITVGSDNQKLNVIVDTGSSDLWIPDS----NVICI--PKWRGDKGDFCKSAGSYSP 143 Query: 459 -----------NCKITYGSGAIS-GFFSNDNVLVGDLVVKNQKF 554 I YG G+ + G D V +G + V++Q F Sbjct: 144 ASSRTSQNLNTRFDIKYGDGSYAKGKLYKDTVGIGGVSVRDQLF 187
>BACE1_RAT (P56819) Beta-secretase 1 precursor (EC 3.4.23.46) (Beta-site APP| cleaving enzyme 1) (Beta-site amyloid precursor protein cleaving enzyme 1) (Aspartyl protease 2) (Asp 2) (ASP2) (Membrane-associated aspartic protease 2) (Memapsin-2) Length = 501 Score = 42.4 bits (98), Expect = 0.001 Identities = 29/93 (31%), Positives = 45/93 (48%), Gaps = 4/93 (4%) Frame = +3 Query: 258 VPLVDYLNTQ----YYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRS 425 V +VD L + YY + +G+PPQ ++ DTGSSN V ++ F LH Y+ Sbjct: 61 VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF-----LHRYYQR 115 Query: 426 SRSTTYKADGENCKITYGSGAISGFFSNDNVLV 524 S+TY+ ++ + Y G G D V + Sbjct: 116 QLSSTYRDLRKSVYVPYTQGKWEGELGTDLVSI 148
>BACE1_MOUSE (P56818) Beta-secretase 1 precursor (EC 3.4.23.46) (Beta-site APP| cleaving enzyme 1) (Beta-site amyloid precursor protein cleaving enzyme 1) (Aspartyl protease 2) (Asp 2) (ASP2) (Membrane-associated aspartic protease 2) (Memapsin-2) Length = 501 Score = 42.0 bits (97), Expect = 0.001 Identities = 29/93 (31%), Positives = 44/93 (47%), Gaps = 4/93 (4%) Frame = +3 Query: 258 VPLVDYLNTQ----YYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRS 425 V +VD L + YY + +G+PPQ ++ DTGSSN V ++ F LH Y+ Sbjct: 61 VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF-----LHRYYQR 115 Query: 426 SRSTTYKADGENCKITYGSGAISGFFSNDNVLV 524 S+TY+ + + Y G G D V + Sbjct: 116 QLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSI 148
>BACE1_HUMAN (P56817) Beta-secretase 1 precursor (EC 3.4.23.46) (Beta-site APP| cleaving enzyme 1) (Beta-site amyloid precursor protein cleaving enzyme 1) (Aspartyl protease 2) (Asp 2) (ASP2) (Membrane-associated aspartic protease 2) (Memapsin-2) Length = 501 Score = 42.0 bits (97), Expect = 0.001 Identities = 29/93 (31%), Positives = 44/93 (47%), Gaps = 4/93 (4%) Frame = +3 Query: 258 VPLVDYLNTQ----YYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIACYLHPKYRS 425 V +VD L + YY + +G+PPQ ++ DTGSSN V ++ F LH Y+ Sbjct: 61 VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF-----LHRYYQR 115 Query: 426 SRSTTYKADGENCKITYGSGAISGFFSNDNVLV 524 S+TY+ + + Y G G D V + Sbjct: 116 QLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSI 148
>PEP2_THUTO (P20140) Pepsin-2 precursor (EC 3.4.23.-) (Fragment)| Length = 72 Score = 41.6 bits (96), Expect = 0.002 Identities = 16/29 (55%), Positives = 22/29 (75%) Frame = +3 Query: 261 PLVDYLNTQYYGVIGLGTPPQNFTVIFDT 347 P+ + + YYGV+ +GTPPQ+F VIFDT Sbjct: 44 PMTNDADLSYYGVVSIGTPPQSFKVIFDT 72
>AXP1_YARLI (Q92389) Acid extracellular protease precursor (EC 3.4.23.-)| Length = 397 Score = 41.2 bits (95), Expect = 0.002 Identities = 27/85 (31%), Positives = 36/85 (42%), Gaps = 7/85 (8%) Frame = +3 Query: 321 QNFTVIFDTGSSNLWVPSSKCYFSIACYLHPK-------YRSSRSTTYKADGENCKITYG 479 Q + DTGS LWV + SIAC + + Y +S+T K G I YG Sbjct: 70 QTISASIDTGSEILWVWEND---SIACQVDQQDCDTDGSYNPKKSSTSKDTGVPFNINYG 126 Query: 480 SGAISGFFSNDNVLVGDLVVKNQKF 554 G G+ DN ++G KF Sbjct: 127 KGHADGYLYTDNAVIGGASAPGFKF 151
>CARP2_CANAL (P28871) Candidapepsin-2 precursor (EC 3.4.23.24) (Aspartate| protease 2) (ACP 2) (Secreted aspartic protease 2) Length = 398 Score = 41.2 bits (95), Expect = 0.002 Identities = 32/96 (33%), Positives = 41/96 (42%), Gaps = 9/96 (9%) Frame = +3 Query: 288 YYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCYFSIA--------CYLHPKYRSSRSTTY 443 Y I +G+ Q VI DTGSS+LWVP + C Y S S+ Sbjct: 70 YAADITVGSNNQKLNVIVDTGSSDLWVPDVNVDCQVTYSDQTADFCKQKGTYDPSGSSAS 129 Query: 444 KADGENCKITYGSGAIS-GFFSNDNVLVGDLVVKNQ 548 + KI YG G+ S G D V G + +KNQ Sbjct: 130 QDLNTPFKIGYGDGSSSQGTLYKDTVGFGGVSIKNQ 165
>YPS1_YEAST (P32329) Aspartic proteinase 3 precursor (EC 3.4.23.41) (Yapsin-1)| Length = 569 Score = 40.8 bits (94), Expect = 0.003 Identities = 18/31 (58%), Positives = 24/31 (77%), Gaps = 1/31 (3%) Frame = +3 Query: 288 YYGV-IGLGTPPQNFTVIFDTGSSNLWVPSS 377 +Y V + +GTPPQN TV+ DTGSS+LW+ S Sbjct: 82 FYSVDLEVGTPPQNVTVLVDTGSSDLWIMGS 112 Score = 33.5 bits (75), Expect = 0.47 Identities = 22/79 (27%), Positives = 40/79 (50%), Gaps = 1/79 (1%) Frame = +3 Query: 345 TGSSNLWVPSSKCYFSIACYLHPKYRSSRSTTYKADGENCKITYGSGAI-SGFFSNDNVL 521 +G++ VP+S+ ++ C + + +S S+T++++ I+YG G SG F D + Sbjct: 170 SGTATQSVPASEA--TMDCQQYGTFSTSGSSTFRSNNTYFSISYGDGTFASGTFGTDVLD 227 Query: 522 VGDLVVKNQKFIEATRETS 578 + DL V F A S Sbjct: 228 LSDLNVTGLSFAVANETNS 246
>ASP2_BLAGE (P54958) Aspartic protease Bla g 2 precursor (EC 3.4.23.-)| (Allergen Bla g II) Length = 352 Score = 40.8 bits (94), Expect = 0.003 Identities = 28/98 (28%), Positives = 47/98 (47%), Gaps = 1/98 (1%) Frame = +3 Query: 273 YLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCY-FSIACYLHPKYRSSRSTTYKA 449 ++NTQY G+ +G QNF +FD+ S N+ V S +C + C KY + Y + Sbjct: 34 FINTQYAGITKIGN--QNFLTVFDSTSCNVVVASQECVGGACVCPNLQKYEKLK-PKYIS 90 Query: 450 DGENCKITYGSGAISGFFSNDNVLVGDLVVKNQKFIEA 563 DG + +G+ G D++ + +L Q + A Sbjct: 91 DGNVQVKFFDTGSAVGRGIEDSLTISNLTTSQQDIVLA 128
>PEPA_ASPSA (Q12567) Aspergillopepsin A precursor (EC 3.4.23.18)| (Aspergillopepsin I) Length = 394 Score = 40.4 bits (93), Expect = 0.004 Identities = 33/84 (39%), Positives = 43/84 (51%), Gaps = 1/84 (1%) Frame = +3 Query: 339 FDTGSSNLWVPSSKCYFSIACYLHPKYRSSRSTTYKADGENCKITYGSG-AISGFFSNDN 515 FDTGS++LWV S + S H Y S S T K G + I+YG G + SG D Sbjct: 100 FDTGSADLWVFSDELPSSEQTG-HDLYTPSSSAT-KLSGYSWDISYGDGSSASGDVYRDT 157 Query: 516 VLVGDLVVKNQKFIEATRETSVSF 587 V VG V N++ +EA + S F Sbjct: 158 VTVGG-VTTNKQAVEAASKISSEF 180
>PEPA_ASPAW (P17946) Aspergillopepsin A precursor (EC 3.4.23.18)| Length = 394 Score = 40.0 bits (92), Expect = 0.005 Identities = 33/84 (39%), Positives = 42/84 (50%), Gaps = 1/84 (1%) Frame = +3 Query: 339 FDTGSSNLWVPSSKCYFSIACYLHPKYRSSRSTTYKADGENCKITYGSG-AISGFFSNDN 515 FDTGS++LWV S + S H Y S S T K G I+YG G + SG D Sbjct: 100 FDTGSADLWVFSDELPSSEQTG-HDLYTPSSSAT-KLSGYTWDISYGDGSSASGDVYRDT 157 Query: 516 VLVGDLVVKNQKFIEATRETSVSF 587 V VG V N++ +EA + S F Sbjct: 158 VTVGG-VTTNKQAVEAASKISSEF 180
>NEP1_NEPGR (Q766C3) Aspartic proteinase nepenthesin-1 precursor (EC 3.4.23.-)| (Nepenthesin-I) Length = 437 Score = 39.3 bits (90), Expect = 0.009 Identities = 28/108 (25%), Positives = 44/108 (40%), Gaps = 18/108 (16%) Frame = +3 Query: 285 QYYGVIGLGTPPQNFTVIFDTGSSNLWV---PSSKCYFSIACYLHPKYRSSRST------ 437 +Y + +GTP Q F+ I DTGS +W P ++C+ +P+ SS ST Sbjct: 94 EYLMNLSIGTPAQPFSAIMDTGSDLIWTQCQPCTQCFNQSTPIFNPQGSSSFSTLPCSSQ 153 Query: 438 ------TYKADGENCKITYGSG---AISGFFSNDNVLVGDLVVKNQKF 554 + C+ TYG G G + + G + + N F Sbjct: 154 LCQALSSPTCSNNFCQYTYGYGDGSETQGSMGTETLTFGSVSIPNITF 201
>PEPA_ASPNG (P55325) Aspergillopepsin A precursor (EC 3.4.23.18)| Length = 394 Score = 37.7 bits (86), Expect = 0.025 Identities = 33/89 (37%), Positives = 44/89 (49%), Gaps = 6/89 (6%) Frame = +3 Query: 339 FDTGSSNLW-----VPSSKCYFSIACYLHPKYRSSRSTTYKADGENCKITYGSG-AISGF 500 FDTGS++LW +PSS+ H Y S S T K G + I+YG G + SG Sbjct: 100 FDTGSADLWGFSDELPSSEQTG------HDLYTPSSSAT-KLSGYSWDISYGDGSSASGD 152 Query: 501 FSNDNVLVGDLVVKNQKFIEATRETSVSF 587 D V VG V N++ +EA + S F Sbjct: 153 VYRDTVTVGG-VTTNKQAVEAASKISSEF 180
>PEPA_ASPOR (Q06902) Aspergillopepsin A precursor (EC 3.4.23.18)| (Aspergillopepsin O) Length = 404 Score = 37.0 bits (84), Expect = 0.042 Identities = 40/137 (29%), Positives = 63/137 (45%), Gaps = 6/137 (4%) Frame = +3 Query: 195 AKAARQYGAL---RLKSG--NSDSDIVPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSN 359 ++A +YG LKS + +V + + +Y + +G N FDTGS++ Sbjct: 59 SRALAKYGGTVPAHLKSAVASGHGTVVTSPEPNDIEYLTPVNIGGTTLNLD--FDTGSAD 116 Query: 360 LWVPSSKCYFSIACYLHPKYRSSRSTTYKADGENCKITYGSG-AISGFFSNDNVLVGDLV 536 LWV S + S H Y+ S + + K G + I+YG G + SG D V VG + Sbjct: 117 LWVFSEELPKSEQTG-HDVYKPSGNAS-KIAGASWDISYGDGSSASGDVYQDTVTVGGVT 174 Query: 537 VKNQKFIEATRETSVSF 587 + Q +EA + S F Sbjct: 175 AQGQA-VEAASKISDQF 190
>PEPC_PIG (P30879) Gastricsin precursor (EC 3.4.23.3) (Pepsinogen C)| (Fragment) Length = 73 Score = 36.6 bits (83), Expect = 0.055 Identities = 22/65 (33%), Positives = 34/65 (52%) Frame = +3 Query: 144 LRINLNKRSLTHESLAAAKAARQYGALRLKSGNSDSDIVPLVDYLNTQYYGVIGLGTPPQ 323 +R + ++ L E L K + A R + G+ + P+ YL Y+G I +GTPPQ Sbjct: 13 IRQAMKEKGLLEEFL---KTHKYDPAQRYRIGDISVALEPMA-YLEAAYFGEISIGTPPQ 68 Query: 324 NFTVI 338 NF V+ Sbjct: 69 NFLVL 73
>PENP_PENJA (P00798) Penicillopepsin (EC 3.4.23.20) (Peptidase A)| Length = 323 Score = 36.6 bits (83), Expect = 0.055 Identities = 29/84 (34%), Positives = 43/84 (51%), Gaps = 1/84 (1%) Frame = +3 Query: 339 FDTGSSNLWVPSSKCYFSIACYLHPKYRSSRSTTYKADGENCKITYGSG-AISGFFSNDN 515 FDTGS++LWV S++ S H Y S +T + G I+YG G + SG D+ Sbjct: 32 FDTGSADLWVFSTELPASQQSG-HSVYNPS-ATGKELSGYTWSISYGDGSSASGNVFTDS 89 Query: 516 VLVGDLVVKNQKFIEATRETSVSF 587 V VG + Q ++A ++ S F Sbjct: 90 VTVGGVTAHGQA-VQAAQQISAQF 112
>CHYM_FELCA (P09873) Chymosin precursor (EC 3.4.23.4) (Fragment)| Length = 54 Score = 35.8 bits (81), Expect = 0.094 Identities = 17/49 (34%), Positives = 30/49 (61%) Frame = +3 Query: 177 HESLAAAKAARQYGALRLKSGNSDSDIVPLVDYLNTQYYGVIGLGTPPQ 323 H+ + KA +++G L S+ PL D+L+++Y+G I +GTPP+ Sbjct: 9 HKGKSLRKALKEHGLLEBFDKVSNE---PLADFLDSEYFGKIYIGTPPZ 54
>PRM2_MOUSE (P07978) Protamine-2 (Protamine-P2) (Sperm histone P2) [Contains:| PP2-A; PP2-C; PP2-D; PP2-B (Protamine MP2)] Length = 107 Score = 35.0 bits (79), Expect = 0.16 Identities = 14/27 (51%), Positives = 16/27 (59%) Frame = -2 Query: 315 ACRGRSPHSTGC*GSRQEARCRCLNCR 235 +CR R H GC SR+ RCRC CR Sbjct: 77 SCRHRRRHRRGCRRSRRRRRCRCRKCR 103
>IRS2_HUMAN (Q9Y4H2) Insulin receptor substrate 2 (IRS-2)| Length = 1338 Score = 33.5 bits (75), Expect = 0.47 Identities = 18/63 (28%), Positives = 27/63 (42%) Frame = +3 Query: 207 RQYGALRLKSGNSDSDIVPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCY 386 R + +L ++D ++P DYLN + GTPP F+ G L CY Sbjct: 744 RMWCGSKLSMEHADGKLLPNGDYLNVSPSDAVTTGTPPDFFSAALHPGGEPLRGVPGCCY 803 Query: 387 FSI 395 S+ Sbjct: 804 SSL 806
>PRM2_RAT (P11248) Protamine-2 (Protamine-P2) (Sperm histone P2)| Length = 104 Score = 32.7 bits (73), Expect = 0.80 Identities = 13/27 (48%), Positives = 15/27 (55%) Frame = -2 Query: 315 ACRGRSPHSTGC*GSRQEARCRCLNCR 235 +CR R H GC SR+ CRC CR Sbjct: 74 SCRHRRRHRRGCRRSRRRRSCRCRKCR 100
>VE2_HPV36 (P50809) Regulatory protein E2| Length = 509 Score = 32.3 bits (72), Expect = 1.0 Identities = 19/45 (42%), Positives = 24/45 (53%), Gaps = 3/45 (6%) Frame = +2 Query: 140 TAKDQPQQEELDP*VSGRGKGREA---VRRPPTEERQFRQRHRAS 265 T +QPQQ E GR GR RRP ++R+ R RHR+S Sbjct: 234 TTSEQPQQTE----TKGRKYGRRPSSRTRRPQAKQRRSRSRHRSS 274
>NEP1_NEPDI (P69476) Aspartic proteinase nepenthesin-1 (EC 3.4.23.-)| (Nepenthesin-I) (Fragments) Length = 164 Score = 31.6 bits (70), Expect = 1.8 Identities = 12/27 (44%), Positives = 17/27 (62%) Frame = +3 Query: 285 QYYGVIGLGTPPQNFTVIFDTGSSNLW 365 +Y + +GTP Q F+ I DTGS +W Sbjct: 16 EYLMXLSIGTPAQPFSAIMDTGSDLIW 42
>ASNS_ASPOF (P31752) Asparagine synthetase [glutamine-hydrolyzing] (EC 6.3.5.4)| (AS) Length = 589 Score = 31.2 bits (69), Expect = 2.3 Identities = 19/70 (27%), Positives = 29/70 (41%) Frame = +3 Query: 159 NKRSLTHESLAAAKAARQYGALRLKSGNSDSDIVPLVDYLNTQYYGVIGLGTPPQNFTVI 338 NK HE+ KA QY LR S + V +L+ ++ V + P++ + Sbjct: 359 NKEEFHHETCRKIKALHQYDCLRANKATSAWGLEARVPFLDKEFMDV-AMSIDPESKMIK 417 Query: 339 FDTGSSNLWV 368 D G WV Sbjct: 418 PDLGRIEKWV 427
>MURA_DEIRA (Q9RVA6) UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC| 2.5.1.7) (Enoylpyruvate transferase) (UDP-N-acetylglucosamine enolpyruvyl transferase) (EPT) Length = 426 Score = 30.8 bits (68), Expect = 3.0 Identities = 18/66 (27%), Positives = 32/66 (48%) Frame = +3 Query: 117 HHASSRDGLLRINLNKRSLTHESLAAAKAARQYGALRLKSGNSDSDIVPLVDYLNTQYYG 296 H S +G L TH ++ AA G + L++ + D+D+V ++++LN Sbjct: 150 HREGSLNGSFVFELLTVGGTHNAILAAALGE--GTVTLENASIDTDVVDVIEFLNALGAR 207 Query: 297 VIGLGT 314 + G GT Sbjct: 208 IEGAGT 213
>PRM2_RATFU (Q91VE1) Protamine-2 (Protamine-P2) (Sperm histone P2)| Length = 105 Score = 30.8 bits (68), Expect = 3.0 Identities = 12/27 (44%), Positives = 15/27 (55%) Frame = -2 Query: 315 ACRGRSPHSTGC*GSRQEARCRCLNCR 235 +C R H GC SR+ RC+C CR Sbjct: 75 SCCHRRRHRRGCRRSRRRRRCKCRKCR 101
>FBN3_HUMAN (Q75N90) Fibrillin-3 precursor| Length = 2809 Score = 30.0 bits (66), Expect = 5.2 Identities = 32/119 (26%), Positives = 43/119 (36%), Gaps = 14/119 (11%) Frame = -2 Query: 528 PQPTHYHC*KIQR------LLQNHM*FCNSHHLLCKWLTCSTCIWGGGSMLSRNSISTRE 367 P PT C I++ +LQ C S + +T + C GGG Sbjct: 2285 PSPTLTECHDIRQGPCFAEVLQT---MCRSLSSSSEAVTRAECCCGGGR----------- 2330 Query: 366 PTGWSSRCRISP*NSAAACRGRSPHSTGC*G-SRQEARCRCL-------NCRSSVGGRR 214 GW RC + P +A R PH +G R CR L C +S+G R Sbjct: 2331 --GWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFR 2387
>IRS2_MOUSE (P81122) Insulin receptor substrate 2 (IRS-2) (4PS)| Length = 1321 Score = 29.6 bits (65), Expect = 6.7 Identities = 20/63 (31%), Positives = 27/63 (42%) Frame = +3 Query: 207 RQYGALRLKSGNSDSDIVPLVDYLNTQYYGVIGLGTPPQNFTVIFDTGSSNLWVPSSKCY 386 R + +L N D ++P DYLN GTPP +F+ GS L CY Sbjct: 736 RMWCGSKLSMENPDPKLLPNGDYLNKSPSEAGTAGTPP-DFSAALRGGSEGLKGIPGHCY 794 Query: 387 FSI 395 S+ Sbjct: 795 SSL 797
>EX53_STRCO (Q9RJ79) Probable 5'-3' exonuclease (EC 3.1.11.-)| Length = 301 Score = 29.6 bits (65), Expect = 6.7 Identities = 13/28 (46%), Positives = 18/28 (64%) Frame = -3 Query: 425 RPVFGVEVACYREIAFRRGNPQVGAPGV 342 R +GV+ A Y ++A RG+P G PGV Sbjct: 173 REKYGVDGAGYADLALLRGDPSDGLPGV 200
>YMV5_CAEEL (P34507) Hypothetical protein K04H4.5| Length = 251 Score = 29.3 bits (64), Expect = 8.8 Identities = 20/54 (37%), Positives = 27/54 (50%), Gaps = 6/54 (11%) Frame = +3 Query: 186 LAAAKAARQYGALRLKSGNSDSD------IVPLVDYLNTQYYGVIGLGTPPQNF 329 +AA +A + + A N + D I P VD +N +YY V G PPQNF Sbjct: 75 IAAEQADKSFYAYEKSDANLEGDKKEVEAIAP-VDSMNFEYY-VPGFSPPPQNF 126
>CISY_RICBE (Q59734) Citrate synthase (EC 2.3.3.1) (Fragment)| Length = 412 Score = 29.3 bits (64), Expect = 8.8 Identities = 16/39 (41%), Positives = 22/39 (56%), Gaps = 3/39 (7%) Frame = +3 Query: 273 YLNTQYY-GVI--GLGTPPQNFTVIFDTGSSNLWVPSSK 380 Y N +Y G+I +G PPQ FTV+F T + W+ K Sbjct: 360 YPNVDFYSGIIYKAMGIPPQMFTVLFATARTVGWMAQWK 398 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 93,655,716 Number of Sequences: 219361 Number of extensions: 2095640 Number of successful extensions: 6553 Number of sequences better than 10.0: 141 Number of HSP's better than 10.0 without gapping: 6264 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6454 length of database: 80,573,946 effective HSP length: 106 effective length of database: 57,321,680 effective search space used: 5101629520 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
