ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | baal19d21 |
|---|---|
| Clone Library Name | barley_pub |
>DHGY_CUCSA (P13443) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-dependent| hydroxypyruvate reductase) (HPR) (GDH) Length = 382 Score = 338 bits (866), Expect = 9e-93 Identities = 160/188 (85%), Positives = 176/188 (93%) Frame = +1 Query: 43 AYARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREAD 222 AYARMM+EGFKMNLIYFDLYQSTRLEKFVTAYG+FLKANGE PVTW+RASSM+EVLREAD Sbjct: 179 AYARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGEFLKANGEAPVTWRRASSMDEVLREAD 238 Query: 223 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 402 VISLHPVLDKTT+HL+N E L MKK+A+L+N SRGPVIDE ALV+HL+ NPMFRVGLDV Sbjct: 239 VISLHPVLDKTTFHLVNKESLKAMKKDAILINCSRGPVIDEAALVDHLRDNPMFRVGLDV 298 Query: 403 FEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNAVEP 582 FEDEPYMKPGLA+MKNA++VPHIASASKWTREGMATLAALNVLGKIKGYPVW +PN VEP Sbjct: 299 FEDEPYMKPGLADMKNAIIVPHIASASKWTREGMATLAALNVLGKIKGYPVWSDPNRVEP 358 Query: 583 FLDEEATP 606 FLDE +P Sbjct: 359 FLDENVSP 366
>GYAR_PYRHO (O58320) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 334 Score = 114 bits (284), Expect = 3e-25 Identities = 64/161 (39%), Positives = 92/161 (57%) Frame = +1 Query: 64 EGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPV 243 +GF M ++Y+ + +E+ + A +E++LRE+D + L Sbjct: 170 KGFNMRILYYSRTRKEEVERELNA----------------EFKPLEDLLRESDFVVLAVP 213 Query: 244 LDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYM 423 L + TYHLIN ERL +MKK A+L+N +RG V+D ALV+ LK + GLDVFE+EPY Sbjct: 214 LTRETYHLINEERLKLMKKTAILINIARGKVVDTNALVKALKEGWIAGAGLDVFEEEPYY 273 Query: 424 KPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 546 L ++ N V+ PHI SAS REGMA L A N++ +G Sbjct: 274 NEELFKLDNVVLTPHIGSASFGAREGMAELVAKNLIAFKRG 314
>GYAR_THELI (Q9C4M5) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 331 Score = 113 bits (283), Expect = 4e-25 Identities = 66/162 (40%), Positives = 91/162 (56%), Gaps = 1/162 (0%) Frame = +1 Query: 64 EGFKMNLIYFDLYQSTRLEKFVTA-YGQFLKANGEQPVTWKRASSMEEVLREADVISLHP 240 +GF M +IY+ + E+ + A Y F E +L+E+D ISLH Sbjct: 170 KGFGMKIIYYSRTRKPEAEEEIGAEYVDF-----------------ETLLKESDFISLHV 212 Query: 241 VLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPY 420 L K TYH+I + L +MK A+L+N SRG V+D AL++ LK + GLDVFE+EPY Sbjct: 213 PLTKETYHMIGEKELKLMKPNAILINTSRGAVVDTNALIKALKEGWIAGAGLDVFEEEPY 272 Query: 421 MKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 546 L ++KN V+ PHI SA+ REGMA L A N++ KG Sbjct: 273 YNEELFKLKNVVLAPHIGSATHEAREGMAELVAKNLIAFAKG 314
>GYAR_PYRAB (Q9UYR1) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 335 Score = 113 bits (282), Expect = 5e-25 Identities = 63/160 (39%), Positives = 91/160 (56%) Frame = +1 Query: 67 GFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVL 246 GF M ++Y+ + +EK + A ++E+LRE+D + L L Sbjct: 172 GFDMRILYYSRTRKPEVEKELNA----------------EFKPLDELLRESDFVVLAVPL 215 Query: 247 DKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMK 426 +K TYH+IN ERL MMK+ A+L+N +RG VID AL++ LK + GLDV+E+EPY Sbjct: 216 NKETYHMINEERLKMMKRTAILINVARGKVIDTKALIKALKEGWIAGAGLDVYEEEPYYN 275 Query: 427 PGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 546 L + N V+ PHI SA+ REGMA L A N++ +G Sbjct: 276 EELFSLDNVVLTPHIGSATFGAREGMAKLVAENLIAFKRG 315
>GYAR_PYRKO (Q5JEZ2) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 333 Score = 107 bits (268), Expect = 2e-23 Identities = 62/155 (40%), Positives = 88/155 (56%) Frame = +1 Query: 67 GFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVL 246 GF M ++Y+ + EK + A S+E++LRE+D + L L Sbjct: 171 GFGMRILYYSRSRKPEAEKELGA----------------EFRSLEDLLRESDFVVLAVPL 214 Query: 247 DKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMK 426 K T ++IN ERL +MKK A+LVN +RG V+D AL++ LK + GLDV+E+EPY Sbjct: 215 TKETQYMINEERLRLMKKTAILVNIARGKVVDTKALMKALKEGWIAGAGLDVYEEEPYYN 274 Query: 427 PGLAEMKNAVVVPHIASASKWTREGMATLAALNVL 531 L +KN V+ PHI SA+ REGMA L A N++ Sbjct: 275 EELFSLKNVVLAPHIGSATYGAREGMAELVARNLI 309
>GYAR_PYRFU (Q8U3Y2) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 336 Score = 104 bits (259), Expect = 2e-22 Identities = 61/161 (37%), Positives = 89/161 (55%) Frame = +1 Query: 64 EGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPV 243 +GF M ++Y+ + ++ EK + A +EEVL+E+D + L Sbjct: 170 KGFNMRILYYSRTRKSQAEKELGA----------------EYRPLEEVLKESDFVILAVP 213 Query: 244 LDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYM 423 L K T ++IN ERL +MK A+LVN +RG V+D AL++ LK + GLDVFE+EPY Sbjct: 214 LTKETMYMINEERLKLMKPTAILVNIARGKVVDTKALIKALKEGWIAGAGLDVFEEEPYY 273 Query: 424 KPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 546 L + N V+ PHI SA+ RE MA L A N++ +G Sbjct: 274 NEELFSLDNVVLTPHIGSATFEAREAMAELVARNLIAFKRG 314
>GYAR_AERPE (Q9YAW4) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 335 Score = 95.1 bits (235), Expect = 1e-19 Identities = 53/120 (44%), Positives = 76/120 (63%), Gaps = 2/120 (1%) Frame = +1 Query: 193 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 372 S+E++LRE+D++S+H L T HLI L +MKK A+LVN RG ++D ALV+ L+ Sbjct: 198 SLEDLLRESDILSIHLPLTDETRHLIGESELKLMKKTAILVNTGRGAIVDTGALVKALRE 257 Query: 373 NPMFRVGLDVFEDEPYMKPG--LAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 546 + LDVFE+EP + P L KN V+ PH ASA++ TR MA +AA N++ +G Sbjct: 258 GWIAAAALDVFEEEP-LNPNHPLTAFKNVVLAPHAASATRETRLRMAMMAAENLVAFAQG 316
>TKRA_ENTAG (P58000) 2-ketogluconate reductase (EC 1.1.1.215) (2KR)| (2-ketoaldonate reductase) Length = 323 Score = 94.7 bits (234), Expect = 2e-19 Identities = 51/118 (43%), Positives = 73/118 (61%), Gaps = 1/118 (0%) Frame = +1 Query: 196 MEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN 375 ++ +LRE+D + + L + T+H+I E+LA MK A+L+NA RGPV+DE AL+ LK Sbjct: 193 LDTLLRESDFLCISLPLTEQTHHMIGREQLAKMKPSAILINAGRGPVVDEQALIAALKDK 252 Query: 376 PMFRVGLDVFEDEPY-MKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 546 + GLDVFE EP + L + N V +PHI SA+ TR GMA A N++ + G Sbjct: 253 TIHAAGLDVFEQEPLPVDSELLTLPNVVALPHIGSATHETRYGMARDAVDNLIAALAG 310
>TKRA_ECOLI (P37666) 2-ketogluconate reductase (EC 1.1.1.215) (2KR)| (2-ketoaldonate reductase) Length = 324 Score = 93.6 bits (231), Expect = 4e-19 Identities = 51/122 (41%), Positives = 71/122 (58%), Gaps = 1/122 (0%) Frame = +1 Query: 184 RASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEH 363 R ++ +L+E+D + L L T+HL E+ A MK A+ +NA RGPV+DE AL+ Sbjct: 190 RYCDLDTLLQESDFVCLILPLTDETHHLFGAEQFAKMKSSAIFINAGRGPVVDENALIAA 249 Query: 364 LKANPMFRVGLDVFEDEPY-MKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKI 540 L+ + GLDVFE EP + L M N V VPHI SA+ TR GMA A N++ + Sbjct: 250 LQKGEIHAAGLDVFEQEPLSVDSPLLSMANVVAVPHIGSATHETRYGMAACAVDNLIDAL 309 Query: 541 KG 546 +G Sbjct: 310 QG 311
>TKRA_ECO57 (P58220) 2-ketogluconate reductase (EC 1.1.1.215) (2KR)| (2-ketoaldonate reductase) Length = 324 Score = 93.6 bits (231), Expect = 4e-19 Identities = 51/122 (41%), Positives = 71/122 (58%), Gaps = 1/122 (0%) Frame = +1 Query: 184 RASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEH 363 R ++ +L+E+D + L L T+HL E+ A MK A+ +NA RGPV+DE AL+ Sbjct: 190 RYCDLDTLLQESDFVCLILPLTDETHHLFGAEQFAKMKSSAIFINAGRGPVVDENALIAA 249 Query: 364 LKANPMFRVGLDVFEDEPY-MKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKI 540 L+ + GLDVFE EP + L M N V VPHI SA+ TR GMA A N++ + Sbjct: 250 LQKGEIHAAGLDVFEQEPLSVDSPLLSMANVVAVPHIGSATHETRYGMAACAVDNLIDAL 309 Query: 541 KG 546 +G Sbjct: 310 QG 311
>YEAA_SCHPO (O14075) Putative 2-hydroxyacid dehydrogenase UNK4.10 (EC 1.-.-.-)| Length = 334 Score = 86.3 bits (212), Expect = 6e-17 Identities = 44/112 (39%), Positives = 69/112 (61%) Frame = +1 Query: 193 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 372 S +++L ++DV+SL+ L+ T H+I MK+ V+VN +RG V+DE ALVE L Sbjct: 202 SFDDLLAKSDVLSLNLPLNAHTRHIIGKPEFQKMKRGIVIVNTARGAVMDEAALVEALDE 261 Query: 373 NPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNV 528 ++ GLDVFE+EP + PGL E + +++PH+ + S T+ M +NV Sbjct: 262 GIVYSAGLDVFEEEPKIHPGLLENEKVILLPHLGTNSLETQYKMECAVLMNV 313
>SERA_METTH (O27051) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 525 Score = 84.0 bits (206), Expect = 3e-16 Identities = 63/181 (34%), Positives = 93/181 (51%), Gaps = 3/181 (1%) Frame = +1 Query: 64 EGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPV 243 + F M+++ +D Y S +A E VT + +E +LRE+D++++H Sbjct: 161 KAFGMDIMVYDPYISK-------------EAAEEMGVT---VTDLETLLRESDIVTIHVP 204 Query: 244 LDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYM 423 L T HLI+ + +MK A +VN +RG +IDE AL LK + LDVFE+EP Sbjct: 205 LTPETRHLISEDEFKLMKDTAFIVNCARGGIIDEDALYRALKDGEIAGAALDVFEEEPPE 264 Query: 424 KPGLAEMKNAVVVPHI-ASASKWTREGMATLAALNVLGKIKGYPVWGNPNAV--EPFLDE 594 L E++N V+ PHI AS S+ R+ AA+ V +IK G P V P +D Sbjct: 265 GSPLLELENVVLTPHIGASTSEAQRD-----AAIIVANEIKTVFQGGAPRNVLNMPVMDS 319 Query: 595 E 597 E Sbjct: 320 E 320
>YN14_YEAST (P53839) Putative 2-hydroxyacid dehydrogenase YNL274C (EC 1.-.-.-)| Length = 350 Score = 83.6 bits (205), Expect = 4e-16 Identities = 49/136 (36%), Positives = 73/136 (53%) Frame = +1 Query: 199 EEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANP 378 EE L+ +D++S++ L+ T+HLIN E + MK V+VN +RG VIDE A+ + L++ Sbjct: 212 EEFLKRSDIVSVNVPLNHNTHHLINAETIEKMKDGVVIVNTARGAVIDEQAMTDALRSGK 271 Query: 379 MFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVW 558 + GLDVFE EP + L M + +PH+ + S TR+ M L N K + Sbjct: 272 IRSAGLDVFEYEPKISKELLSMSQVLGLPHMGTHSVETRKKMEELVVENA----KNVILT 327 Query: 559 GNPNAVEPFLDEEATP 606 G + P L E P Sbjct: 328 GKVLTIVPELQNEDWP 343
>SERA_METJA (Q58424) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 524 Score = 82.4 bits (202), Expect = 9e-16 Identities = 43/140 (30%), Positives = 75/140 (53%) Frame = +1 Query: 127 VTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEA 306 + Y ++ + + + + E+ + AD I+LH L T H+I E++A+MKK A Sbjct: 165 IIGYDPYIPKEVAESMGVELVDDINELCKRADFITLHVPLTPKTRHIIGREQIALMKKNA 224 Query: 307 VLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASK 486 ++VN +RG +IDE AL E LK + LDVFE+EP L + N + PH ++++ Sbjct: 225 IIVNCARGGLIDEKALYEALKEGKIRAAALDVFEEEPPKDNPLLTLDNVIGTPHQGASTE 284 Query: 487 WTREGMATLAALNVLGKIKG 546 ++ T+ A + ++G Sbjct: 285 EAQKAAGTIVAEQIKKVLRG 304
>SERA_BACSU (P35136) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 525 Score = 82.4 bits (202), Expect = 9e-16 Identities = 50/136 (36%), Positives = 72/136 (52%) Frame = +1 Query: 193 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 372 + EEVL AD+I++H L K T L+N E +A KK L+N +RG +IDE AL+E L+ Sbjct: 185 TFEEVLESADIITVHTPLTKETKGLLNKETIAKTKKGVRLINCARGGIIDEAALLEALEN 244 Query: 373 NPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYP 552 + LDVFE EP + L + + PH+ +++K + +A + VL KG P Sbjct: 245 GHVAGAALDVFEVEPPVDNKLVDHPLVIATPHLGASTKEAQLNVAAQVSEEVLQFAKGLP 304 Query: 553 VWGNPNAVEPFLDEEA 600 V N DE A Sbjct: 305 VMSAINLPAMTKDEFA 320
>Y1556_HAEIN (P45250) Putative 2-hydroxyacid dehydrogenase HI1556 (EC 1.-.-.-)| Length = 315 Score = 82.0 bits (201), Expect = 1e-15 Identities = 46/100 (46%), Positives = 61/100 (61%), Gaps = 5/100 (5%) Frame = +1 Query: 199 EEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANP 378 +EVL++AD+++LH L +TT LIN E L+ MKK A L+N RGP+IDE+ALV+ LK Sbjct: 191 DEVLKQADIVTLHCPLTETTKDLINAETLSKMKKGAFLINTGRGPLIDELALVDALKTGH 250 Query: 379 MFRVGLDVFEDEPYMKP-----GLAEMKNAVVVPHIASAS 483 + LDV EP K M N ++ PHIA AS Sbjct: 251 LGGAALDVMVKEPPEKDNPLILAAKTMPNLIITPHIAWAS 290
>TKRA_BACSU (O32264) Probable 2-ketogluconate reductase (EC 1.1.1.215) (2KR)| Length = 325 Score = 80.1 bits (196), Expect = 5e-15 Identities = 53/154 (34%), Positives = 78/154 (50%), Gaps = 6/154 (3%) Frame = +1 Query: 103 QSTRLEKF-----VTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHL 267 Q+ R KF V + + K E + K A ++ +L ++D I L L TYH+ Sbjct: 162 QAARRAKFGFDMEVLYHNRHRKQETEDSIGVKYAE-LDTLLEQSDFILLITPLTDETYHM 220 Query: 268 INPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPG-LAEM 444 I +MK A+ VN SRG +DE AL+ L+ + GLDV+E EP + L ++ Sbjct: 221 IGEREFKLMKNSAIFVNISRGKTVDEKALIRALQEGWIRGAGLDVYEKEPVTQDNPLLQL 280 Query: 445 KNAVVVPHIASASKWTREGMATLAALNVLGKIKG 546 N ++PHI SA+ R M AA N+L I+G Sbjct: 281 DNVTLLPHIGSATAKVRFNMCKQAAENMLAAIQG 314
>SERA_ARATH (O04130) D-3-phosphoglycerate dehydrogenase, chloroplast precursor| (EC 1.1.1.95) (3-PGDH) Length = 624 Score = 80.1 bits (196), Expect = 5e-15 Identities = 54/141 (38%), Positives = 75/141 (53%), Gaps = 3/141 (2%) Frame = +1 Query: 193 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 372 S ++ + AD +SLH L T + N E + MKK L+N +RG VIDE ALV L A Sbjct: 268 SFDQAISTADFVSLHMPLTPATKKVFNDETFSKMKKGVRLINVARGGVIDEDALVRALDA 327 Query: 373 NPMFRVGLDVFEDEPYMKPG-LAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGY 549 + + LDVF +EP K L + +N V PH+ +++K +EG+A A V G +KG Sbjct: 328 GIVAQAALDVFCEEPPSKDSRLIQHENVTVTPHLGASTKEAQEGVAIEIAEAVAGALKGE 387 Query: 550 PVWGNPNA--VEPFLDEEATP 606 NA V P + E TP Sbjct: 388 LSATAVNAPMVAPEVLSELTP 408
>SERA_ARCFU (O29445) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 527 Score = 79.3 bits (194), Expect = 8e-15 Identities = 51/159 (32%), Positives = 82/159 (51%), Gaps = 3/159 (1%) Frame = +1 Query: 115 LEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMM 294 LE V AY F+ + + K + +L +DVI++H K T LI + M Sbjct: 161 LEMNVLAYDPFVSKERAEQIGVKLVD-FDTLLASSDVITVHVPRTKETIGLIGKGQFEKM 219 Query: 295 KKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPG-LAEMKNAVVVPHI 471 K ++VNA+RG ++DE AL E +KA + LDV+E EP L ++ N V PHI Sbjct: 220 KDGVIVVNAARGGIVDEAALYEAIKAGKVAAAALDVYEKEPPSPDNPLLKLDNVVTTPHI 279 Query: 472 ASASKWTREGMATLAALNVLGKIKGYPVWGNPN--AVEP 582 A++++ + + + A +++ KG PV N ++EP Sbjct: 280 AASTREAQLNVGMIIAEDIVNMAKGLPVRNAVNLPSIEP 318
>DHGY_METEX (Q59516) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-dependent| hydroxypyruvate reductase) (HPR) (GDH) (Hydroxypyruvate dehydrogenase) (Glyoxylate reductase) (HPR-A) Length = 313 Score = 78.2 bits (191), Expect = 2e-14 Identities = 44/122 (36%), Positives = 69/122 (56%), Gaps = 3/122 (2%) Frame = +1 Query: 196 MEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN 375 +E +L ++DVI+LH L T ++I E+L MK+ A+L+N +RG ++DE AL++ LK Sbjct: 186 LETILTQSDVITLHVPLTPDTKNMIGAEQLKKMKRSAILINTARGGLVDEAALLQALKDG 245 Query: 376 PMFRVGLDVFEDEPYMKPGL---AEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 546 + G DV EP + A++ N +V PH+A ASK + +A NV + G Sbjct: 246 TIGGAGFDVVAQEPPKDGNILCDADLPNLIVTPHVAWASKEAMQILADQLVDNVEAFVAG 305 Query: 547 YP 552 P Sbjct: 306 KP 307
>CTBP2_MOUSE (P56546) C-terminal-binding protein 2 (CtBP2)| Length = 445 Score = 74.7 bits (182), Expect = 2e-13 Identities = 48/144 (33%), Positives = 78/144 (54%), Gaps = 6/144 (4%) Frame = +1 Query: 127 VTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEA 306 V Y +L+ E+ + +R +++++L ++D +SLH L++ +HLIN + M++ A Sbjct: 206 VIFYDPYLQDGIERSLGVQRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGA 265 Query: 307 VLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEP--YMKPGLAEMKNAVVVPHIA-- 474 LVNA+RG ++DE AL + LK + LDV E EP + + L + N + PH A Sbjct: 266 FLVNAARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFAQGPLKDAPNLICTPHTAWY 325 Query: 475 --SASKWTREGMATLAALNVLGKI 540 AS RE AT + G+I Sbjct: 326 SEQASLEMREAAATEIRRAITGRI 349
>CTBP2_HUMAN (P56545) C-terminal-binding protein 2 (CtBP2)| Length = 445 Score = 74.7 bits (182), Expect = 2e-13 Identities = 48/144 (33%), Positives = 78/144 (54%), Gaps = 6/144 (4%) Frame = +1 Query: 127 VTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEA 306 V Y +L+ E+ + +R +++++L ++D +SLH L++ +HLIN + M++ A Sbjct: 206 VIFYDPYLQDGIERSLGVQRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGA 265 Query: 307 VLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEP--YMKPGLAEMKNAVVVPHIA-- 474 LVNA+RG ++DE AL + LK + LDV E EP + + L + N + PH A Sbjct: 266 FLVNAARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFAQGPLKDAPNLICTPHTAWY 325 Query: 475 --SASKWTREGMATLAALNVLGKI 540 AS RE AT + G+I Sbjct: 326 SEQASLEMREAAATEIRRAITGRI 349
>PDXB_PHOLL (Q7N2B2) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 375 Score = 74.7 bits (182), Expect = 2e-13 Identities = 44/109 (40%), Positives = 69/109 (63%), Gaps = 4/109 (3%) Frame = +1 Query: 193 SMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 360 S+E++++EAD+++ H L+K+ T+HL++ E L+++ +L+NASRG VID AL+ Sbjct: 160 SLEKLVKEADILTFHTPLNKSGPYKTHHLVDVELLSVLPDNRILINASRGEVIDNQALLT 219 Query: 361 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 507 LK RV LDV+E EP + L E+ + + PHIA +T EG A Sbjct: 220 ALKCGKKLRVVLDVWEPEPDLSLPLLELVD-IGTPHIAG---YTLEGKA 264
>SERA_MYCLE (O33116) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 528 Score = 73.6 bits (179), Expect = 4e-13 Identities = 46/138 (33%), Positives = 72/138 (52%) Frame = +1 Query: 193 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 372 S +++L AD IS+H T LI+ E LA K ++VNA+RG ++DEVAL + +++ Sbjct: 188 SFDDLLARADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLVDEVALADAVRS 247 Query: 373 NPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYP 552 + GLDVF EP L E+ VV PH+ +++ ++ T A +V + G Sbjct: 248 GHVRAAGLDVFATEPCTDSPLFELSQVVVTPHLGASTAEAQDRAGTDVAESVRLALAGEF 307 Query: 553 VWGNPNAVEPFLDEEATP 606 V N ++EE P Sbjct: 308 VPDAVNVDGGVVNEEVAP 325
>SERA_HAEIN (P43885) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 410 Score = 72.4 bits (176), Expect = 1e-12 Identities = 45/129 (34%), Positives = 70/129 (54%), Gaps = 6/129 (4%) Frame = +1 Query: 181 KRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 360 K+ S+EE+L DV+SLH +T +L+N R+A +K+ A+L+NA+RG V+D AL + Sbjct: 193 KQVRSLEELLSSCDVVSLHVPELPSTKNLMNVARIAQLKQGAILINAARGTVVDIDALAQ 252 Query: 361 HLKANPMFRVGLDVFEDEP------YMKPGLAEMKNAVVVPHIASASKWTREGMATLAAL 522 LK + +DVF EP ++ P L E N ++ PHI ++ +E + Sbjct: 253 ALKDGKLQGAAIDVFPVEPASINEEFISP-LREFDNVILTPHIGGSTAEAQENI----GF 307 Query: 523 NVLGKIKGY 549 V GK Y Sbjct: 308 EVAGKFVKY 316
>SERA_SYNY3 (P73821) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 554 Score = 72.4 bits (176), Expect = 1e-12 Identities = 41/119 (34%), Positives = 64/119 (53%) Frame = +1 Query: 196 MEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN 375 ++ + EAD I+LH T +LIN E LA MK A ++N SRG +IDE ALV ++ Sbjct: 215 LDLLFSEADFITLHIPKTPETANLINAETLAKMKPTARIINCSRGGIIDEEALVTAIETA 274 Query: 376 PMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYP 552 + LDVF EP + L E N ++ PH+ ++++ + +A A + + G P Sbjct: 275 QIGGAALDVFAQEPLGESRLREFSNVILTPHLGASTEEAQVNVAVDVAEQIRDVLLGLP 333
>LDHD_LACDE (P26297) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 332 Score = 71.6 bits (174), Expect = 2e-12 Identities = 50/177 (28%), Positives = 87/177 (49%), Gaps = 14/177 (7%) Frame = +1 Query: 58 MIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLH 237 ++EGF +I +D++++ LEK G ++ S++++ ++ADVISLH Sbjct: 163 IMEGFGAKVIAYDIFRNPELEK----KGYYV-------------DSLDDLYKQADVISLH 205 Query: 238 PVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDE- 414 H+IN + +A MK++ V+VN SRGP++D A++ L + +F +DV+E E Sbjct: 206 VPDVPANVHMINDKSIAKMKQDVVIVNVSRGPLVDTDAVIRGLDSGKVFGYAMDVYEGEV 265 Query: 415 ----------PYMKPGLAEM---KNAVVVPHIASASKWTREGMATLAALNVLGKIKG 546 + LA++ N +V PH A + M A N L ++G Sbjct: 266 GVFNEDREGKEFPDARLADLIARPNVLVTPHTAFYTTHAVRNMVVKAFDNNLELVEG 322
>SERA_MYCTU (P0A544) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 528 Score = 71.2 bits (173), Expect = 2e-12 Identities = 45/138 (32%), Positives = 70/138 (50%) Frame = +1 Query: 193 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 372 S++++L AD IS+H T LI+ E LA K ++VNA+RG ++DE AL + + Sbjct: 188 SLDDLLARADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLVDEAALADAITG 247 Query: 373 NPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYP 552 + GLDVF EP L E+ VV PH+ +++ ++ T A +V + G Sbjct: 248 GHVRAAGLDVFATEPCTDSPLFELAQVVVTPHLGASTAEAQDRAGTDVAESVRLALAGEF 307 Query: 553 VWGNPNAVEPFLDEEATP 606 V N ++EE P Sbjct: 308 VPDAVNVGGGVVNEEVAP 325
>SERA_MYCBO (P0A545) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 528 Score = 71.2 bits (173), Expect = 2e-12 Identities = 45/138 (32%), Positives = 70/138 (50%) Frame = +1 Query: 193 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 372 S++++L AD IS+H T LI+ E LA K ++VNA+RG ++DE AL + + Sbjct: 188 SLDDLLARADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLVDEAALADAITG 247 Query: 373 NPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYP 552 + GLDVF EP L E+ VV PH+ +++ ++ T A +V + G Sbjct: 248 GHVRAAGLDVFATEPCTDSPLFELAQVVVTPHLGASTAEAQDRAGTDVAESVRLALAGEF 307 Query: 553 VWGNPNAVEPFLDEEATP 606 V N ++EE P Sbjct: 308 VPDAVNVGGGVVNEEVAP 325
>CTBP1_HUMAN (Q13363) C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1)| Length = 440 Score = 71.2 bits (173), Expect = 2e-12 Identities = 45/142 (31%), Positives = 74/142 (52%), Gaps = 2/142 (1%) Frame = +1 Query: 127 VTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEA 306 V Y +L E+ + +R S+++++L +D ++LH L++ +HLIN + M++ A Sbjct: 200 VLFYDPYLSDGVERALGLQRVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGA 259 Query: 307 VLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEP--YMKPGLAEMKNAVVVPHIASA 480 LVN +RG ++DE AL + LK + LDV E EP + + L + N + PH A Sbjct: 260 FLVNTARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHAAWY 319 Query: 481 SKWTREGMATLAALNVLGKIKG 546 S+ M AA + I G Sbjct: 320 SEQASIEMREEAAREIRRAITG 341
>GRHPR_HUMAN (Q9UBQ7) Glyoxylate reductase/hydroxypyruvate reductase (EC| 1.1.1.79) Length = 328 Score = 70.9 bits (172), Expect = 3e-12 Identities = 44/122 (36%), Positives = 66/122 (54%), Gaps = 1/122 (0%) Frame = +1 Query: 193 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 372 S E+ ++D I + L T L N + MK+ AV +N SRG V+++ L + L + Sbjct: 201 STPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALAS 260 Query: 373 NPMFRVGLDVFEDEPY-MKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGY 549 + GLDV EP L +KN V++PHI SA+ TR M+ LAA N+L ++G Sbjct: 261 GKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNTMSLLAANNLLAGLRGE 320 Query: 550 PV 555 P+ Sbjct: 321 PM 322
>CTBPA_XENLA (Q9YHU0) C-terminal-binding protein A (CtBP)| Length = 440 Score = 70.9 bits (172), Expect = 3e-12 Identities = 44/139 (31%), Positives = 73/139 (52%), Gaps = 2/139 (1%) Frame = +1 Query: 136 YGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLV 315 Y +L E+ + +R S+++++L +D ++LH L++ +HLIN + M++ A LV Sbjct: 203 YDPYLSDGIERALGLQRVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTIKQMRQGAFLV 262 Query: 316 NASRGPVIDEVALVEHLKANPMFRVGLDVFEDEP--YMKPGLAEMKNAVVVPHIASASKW 489 N +RG ++DE AL + LK + LDV E EP + + L + N + PH A S+ Sbjct: 263 NTARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFTQGPLKDAPNLICTPHAAWYSEQ 322 Query: 490 TREGMATLAALNVLGKIKG 546 M AA + I G Sbjct: 323 ASIEMREEAAREIRRAITG 341
>CTBP1_MOUSE (O88712) C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1)| Length = 440 Score = 70.9 bits (172), Expect = 3e-12 Identities = 45/142 (31%), Positives = 74/142 (52%), Gaps = 2/142 (1%) Frame = +1 Query: 127 VTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEA 306 V Y +L E+ + +R S+++++L +D ++LH L++ +HLIN + M++ A Sbjct: 200 VLFYDPYLSDGIERALGLQRVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGA 259 Query: 307 VLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEP--YMKPGLAEMKNAVVVPHIASA 480 LVN +RG ++DE AL + LK + LDV E EP + + L + N + PH A Sbjct: 260 FLVNTARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHAAWY 319 Query: 481 SKWTREGMATLAALNVLGKIKG 546 S+ M AA + I G Sbjct: 320 SEQASIEMREEAAREIRRAITG 341
>CTBP1_RAT (Q9Z2F5) C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1)| (C-terminal-binding protein 3) (CtBP3) (50 kDa BFA-dependent ADP-ribosylation substrate) (BARS-50) Length = 430 Score = 70.9 bits (172), Expect = 3e-12 Identities = 45/142 (31%), Positives = 74/142 (52%), Gaps = 2/142 (1%) Frame = +1 Query: 127 VTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEA 306 V Y +L E+ + +R S+++++L +D ++LH L++ +HLIN + M++ A Sbjct: 189 VLFYDPYLSDGIERALGLQRVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGA 248 Query: 307 VLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEP--YMKPGLAEMKNAVVVPHIASA 480 LVN +RG ++DE AL + LK + LDV E EP + + L + N + PH A Sbjct: 249 FLVNTARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHAAWY 308 Query: 481 SKWTREGMATLAALNVLGKIKG 546 S+ M AA + I G Sbjct: 309 SEQASIEMREEAAREIRRAITG 330
>PDXB_VIBVY (Q7MIT6) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 377 Score = 70.9 bits (172), Expect = 3e-12 Identities = 40/99 (40%), Positives = 60/99 (60%), Gaps = 4/99 (4%) Frame = +1 Query: 190 SSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALV 357 +S++ +L+EADVI+LH + + T+HLIN E L ++ + +L+NA+RGPV+D AL Sbjct: 160 TSLDRLLQEADVITLHTPITRDGKYPTHHLINKEILNSLRADQILINAARGPVVDNQALK 219 Query: 358 EHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIA 474 L+ F LDVFE EP + L + A PH+A Sbjct: 220 HRLQQADGFTAALDVFEFEPEVDMELLPLL-AFATPHVA 257
>PDXB_VIBVU (Q8DB36) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 377 Score = 70.9 bits (172), Expect = 3e-12 Identities = 40/99 (40%), Positives = 60/99 (60%), Gaps = 4/99 (4%) Frame = +1 Query: 190 SSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALV 357 +S++ +L+EADVI+LH + + T+HLIN E L ++ + +L+NA+RGPV+D AL Sbjct: 160 TSLDRLLQEADVITLHTPITRDGKYPTHHLINEEILNSLRADQILINAARGPVVDNQALK 219 Query: 358 EHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIA 474 L+ F LDVFE EP + L + A PH+A Sbjct: 220 RRLQQADGFMAALDVFEFEPEVDMELLPLL-AFATPHVA 257
>PDXB_PSEAE (Q9I3W9) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 380 Score = 70.9 bits (172), Expect = 3e-12 Identities = 45/101 (44%), Positives = 58/101 (57%), Gaps = 4/101 (3%) Frame = +1 Query: 193 SMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 360 S+E +L EADVISLH L++ T HL++ RLA ++ LVNASRG V+D AL Sbjct: 160 SLERLLAEADVISLHTPLNRDGEHPTRHLLDEPRLAALRPGTWLVNASRGAVVDNQALRR 219 Query: 361 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 483 L+ V LDV+E EP P LA + + PHIA S Sbjct: 220 LLEGGADLEVALDVWEGEPQADPELA-ARCLIATPHIAGYS 259
>PDXB_PSEPK (Q88L20) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 380 Score = 70.5 bits (171), Expect = 4e-12 Identities = 44/101 (43%), Positives = 60/101 (59%), Gaps = 4/101 (3%) Frame = +1 Query: 193 SMEEVLREADVISLHPVLDK----TTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 360 S+E +L++ DVISLH L + T+HL+ +LA ++ A LVNASRGPV+D VAL E Sbjct: 159 SLETILQQCDVISLHTPLQRGGQHPTWHLLGQAQLAQLRPGAWLVNASRGPVVDNVALRE 218 Query: 361 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 483 L LDV+E EP + LA++ + PHIA S Sbjct: 219 LLLDREDVHAVLDVWEGEPQVDLQLADL-CTLATPHIAGYS 258
>PDXB_PSESM (Q884R9) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 380 Score = 70.1 bits (170), Expect = 5e-12 Identities = 41/101 (40%), Positives = 62/101 (61%), Gaps = 4/101 (3%) Frame = +1 Query: 193 SMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 360 S++E+L+ DVISLH LDK+ T+HL++ RL +++ A L+NASRG V+D AL + Sbjct: 159 SLDEILQRCDVISLHTPLDKSGQSPTWHLLDEARLRQLRQGAWLINASRGAVVDNRALHD 218 Query: 361 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 483 + + LDV+E EP + LA++ + PHIA S Sbjct: 219 VMLEREDLQAVLDVWEGEPQVNVALADL-CVIGTPHIAGYS 258
>CTBP_DROME (O46036) C-terminal-binding protein (CtBP protein) (dCtBP)| Length = 476 Score = 68.9 bits (167), Expect = 1e-11 Identities = 42/142 (29%), Positives = 72/142 (50%), Gaps = 2/142 (1%) Frame = +1 Query: 127 VTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEA 306 V Y +L ++ + R +++++L ++D +SLH L++ +HLIN + M+ A Sbjct: 200 VIFYDPYLPDGIDKSLGLTRVYTLQDLLFQSDCVSLHCTLNEHNHHLINEFTIKQMRPGA 259 Query: 307 VLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPY--MKPGLAEMKNAVVVPHIASA 480 LVN +RG ++D+ L LK + LDV E+EPY + L + N + PH A Sbjct: 260 FLVNTARGGLVDDETLALALKQGRIRAAALDVHENEPYNVFQGALKDAPNLICTPHAAFF 319 Query: 481 SKWTREGMATLAALNVLGKIKG 546 S + + +AA + I G Sbjct: 320 SDASATELREMAATEIRRAIVG 341
>CTBPB_XENLA (Q9W758) C-terminal-binding protein B (TCF-3 corepressor CtBP)| (XCtBP) Length = 437 Score = 68.2 bits (165), Expect = 2e-11 Identities = 39/118 (33%), Positives = 65/118 (55%), Gaps = 2/118 (1%) Frame = +1 Query: 127 VTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEA 306 V Y +L E+ + +R ++++E+L +D I+LH L++ +HLIN + M++ Sbjct: 203 VIFYDPYLADGVERSLGLQRMATLQELLMHSDCITLHCNLNEHNHHLINDFTIKQMRQGC 262 Query: 307 VLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEP--YMKPGLAEMKNAVVVPHIA 474 LVN +RG ++DE AL + LK + LDV E EP + + L + N + PH A Sbjct: 263 FLVNTARGGLVDEKALAQALKDGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHTA 320
>DDH_ZYMMO (P30799) 2-hydroxyacid dehydrogenase homolog (EC 1.1.1.-)| Length = 331 Score = 67.8 bits (164), Expect = 2e-11 Identities = 42/123 (34%), Positives = 63/123 (51%) Frame = +1 Query: 46 YARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADV 225 +A +M GF N+I + + L K V R +S++EV+ +D+ Sbjct: 159 FAHIMTHGFGANVIAYKPHPDPELAKKVGF----------------RFTSLDEVIETSDI 202 Query: 226 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVF 405 ISLH L +H+IN E LA KK LVN SRG ++D A+++ LKA + DV+ Sbjct: 203 ISLHCPLTPENHHMINEETLARAKKGFYLVNTSRGGLVDTKAVIKSLKAKHLGGYAADVY 262 Query: 406 EDE 414 E+E Sbjct: 263 EEE 265
>PDXB_VIBCH (Q9KQ92) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 381 Score = 67.4 bits (163), Expect = 3e-11 Identities = 47/137 (34%), Positives = 71/137 (51%), Gaps = 6/137 (4%) Frame = +1 Query: 190 SSMEEVLREADVISLHPVLDK----TTYHLINPERLAMMKKEAVLVNASRGPVIDEVALV 357 + +E +L++ADVI+LH + + T+HLI+ L ++ + +L+NA+RGPV+D AL Sbjct: 160 TELETLLKQADVITLHTPITRGGEWPTHHLIDAAILEQLRSDQILINAARGPVVDNAALK 219 Query: 358 EHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA--TLAALNVL 531 L+ F LDVFE EP + L + A PHIA + EG A T N Sbjct: 220 ARLQQGDGFTAVLDVFEFEPQVDMELLPLL-AFATPHIAG---YGLEGKARGTTMIFNSY 275 Query: 532 GKIKGYPVWGNPNAVEP 582 + G NP ++ P Sbjct: 276 CEFLGSAHCANPASLLP 292
>SERA_RAT (O08651) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 66.6 bits (161), Expect = 5e-11 Identities = 38/126 (30%), Positives = 64/126 (50%) Frame = +1 Query: 196 MEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN 375 +EE+ D I++H L +T L+N A KK +VN +RG ++DE AL+ L++ Sbjct: 192 LEEIWPLCDFITVHTPLLPSTTGLLNDSTFAQCKKGVRVVNCARGGIVDEGALLRALQSG 251 Query: 376 PMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPV 555 LDVF +EP L + +N + PH+ +++K + A+ + +KG + Sbjct: 252 QCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSL 311 Query: 556 WGNPNA 573 G NA Sbjct: 312 TGVVNA 317
>SERA_MOUSE (Q61753) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| (A10) Length = 532 Score = 66.6 bits (161), Expect = 5e-11 Identities = 38/126 (30%), Positives = 64/126 (50%) Frame = +1 Query: 196 MEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN 375 +EE+ D I++H L +T L+N A KK +VN +RG ++DE AL+ L++ Sbjct: 192 LEEIWPLCDFITVHTPLLPSTTGLLNDSTFAQCKKGVRVVNCARGGIVDEGALLRALQSG 251 Query: 376 PMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPV 555 LDVF +EP L + +N + PH+ +++K + A+ + +KG + Sbjct: 252 QCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSL 311 Query: 556 WGNPNA 573 G NA Sbjct: 312 TGVVNA 317
>SERA_HUMAN (O43175) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 66.6 bits (161), Expect = 5e-11 Identities = 38/126 (30%), Positives = 64/126 (50%) Frame = +1 Query: 196 MEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN 375 +EE+ D I++H L +T L+N A KK +VN +RG ++DE AL+ L++ Sbjct: 192 LEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSG 251 Query: 376 PMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPV 555 LDVF +EP L + +N + PH+ +++K + A+ + +KG + Sbjct: 252 QCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSL 311 Query: 556 WGNPNA 573 G NA Sbjct: 312 TGVVNA 317
>SERA_PONPY (Q5R7M2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 66.2 bits (160), Expect = 7e-11 Identities = 38/126 (30%), Positives = 64/126 (50%) Frame = +1 Query: 196 MEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN 375 +EE+ D I++H L +T L+N A KK +VN +RG ++DE AL+ L++ Sbjct: 192 LEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSG 251 Query: 376 PMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPV 555 LDVF +EP L + +N + PH+ +++K + A+ + +KG + Sbjct: 252 QCAGAALDVFTEEPPRGRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSL 311 Query: 556 WGNPNA 573 G NA Sbjct: 312 TGVVNA 317
>SERA_MACFA (Q60HD7) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 66.2 bits (160), Expect = 7e-11 Identities = 38/126 (30%), Positives = 64/126 (50%) Frame = +1 Query: 196 MEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN 375 +EE+ D I++H L +T L+N A KK +VN +RG ++DE AL+ L++ Sbjct: 192 LEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSG 251 Query: 376 PMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPV 555 LDVF +EP L + +N + PH+ +++K + A+ + +KG + Sbjct: 252 QCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSL 311 Query: 556 WGNPNA 573 G NA Sbjct: 312 AGVVNA 317
>SERA_BOVIN (Q5EAD2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 66.2 bits (160), Expect = 7e-11 Identities = 38/126 (30%), Positives = 63/126 (50%) Frame = +1 Query: 196 MEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN 375 +E++ D I++H L +T L+N A KK +VN +RG ++DE AL+ L++ Sbjct: 192 LEQIWPLCDFITVHTPLLPSTTGLLNDSTFAQCKKGVCVVNCARGGIVDEGALLRALQSG 251 Query: 376 PMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPV 555 LDVF +EP L +N + PH+ +++K + AL + +KG + Sbjct: 252 QCAGAALDVFTEEPPRDRALVNHENVISCPHLGASTKEAQSRCGEEIALQFVDMVKGKAL 311 Query: 556 WGNPNA 573 G NA Sbjct: 312 AGVVNA 317
>LDHD_LACHE (P30901) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 336 Score = 65.9 bits (159), Expect = 9e-11 Identities = 50/177 (28%), Positives = 83/177 (46%), Gaps = 14/177 (7%) Frame = +1 Query: 58 MIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLH 237 ++EGF +I +D++++ LEK G ++ S++++ ++ADVISLH Sbjct: 163 IMEGFGAKVIAYDIFKNPELEK----KGYYV-------------DSLDDLYKQADVISLH 205 Query: 238 PVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDE- 414 H+IN + +A MK V+VN SRG ++D A++ L + +F +D +EDE Sbjct: 206 VPDVPANVHMINDKSIAEMKDGVVIVNCSRGRLVDTDAVIRGLDSGKIFGFVMDTYEDEV 265 Query: 415 ----------PYMKPGLAEM---KNAVVVPHIASASKWTREGMATLAALNVLGKIKG 546 + LA++ N +V PH A + M A N L I G Sbjct: 266 GVFNKDWEGKEFPDKRLADLIDRPNVLVTPHTAFYTTHAVRNMVVKAFNNNLKLING 322
>YPRB2_CORML (P0C1E9) Hypothetical protein in proB 3'region (EC 1.-.-.-)| Length = 304 Score = 65.9 bits (159), Expect = 9e-11 Identities = 43/111 (38%), Positives = 55/111 (49%), Gaps = 1/111 (0%) Frame = +1 Query: 199 EEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANP 378 E V EADV L L TY ++N E L MK AVLVN RGP+I+ LV+ L Sbjct: 175 EHVWAEADVFVLILPLTDATYQIVNAETLGKMKPSAVLVNVGRGPLINTDDLVDALNNGT 234 Query: 379 MFRVGLDVFEDEPYM-KPGLAEMKNAVVVPHIASASKWTREGMATLAALNV 528 + LDV + EP L EM N V+ PH A+ ++ R L N+ Sbjct: 235 IAGAALDVTDPEPLPDSHPLWEMDNVVITPHTANTNERIRALTGELTLRNI 285
>GRHPR_MOUSE (Q91Z53) Glyoxylate reductase/hydroxypyruvate reductase (EC| 1.1.1.79) Length = 328 Score = 65.5 bits (158), Expect = 1e-10 Identities = 41/117 (35%), Positives = 64/117 (54%), Gaps = 2/117 (1%) Frame = +1 Query: 202 EVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPM 381 ++ E+D I + L T L + + MK A+ +N SRG V+++ L + L + + Sbjct: 204 QLAAESDFIVVSCSLTPDTMGLCSKDFFQKMKNTAIFINISRGDVVNQEDLYQALASGQI 263 Query: 382 FRVGLDVFEDEPYMKPG--LAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 546 GLDV EP + P L +KN V++PHI SA+ TR M+ LAA N+L ++G Sbjct: 264 AAAGLDVTTPEP-LPPSHPLLTLKNCVILPHIGSATYKTRNTMSLLAANNLLAGLRG 319
>LDHD_TREPA (O83080) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 331 Score = 65.5 bits (158), Expect = 1e-10 Identities = 43/123 (34%), Positives = 60/123 (48%), Gaps = 14/123 (11%) Frame = +1 Query: 178 WKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALV 357 W SM+E+L +DVISLH K ++HLIN + +A MK LVN +RG VID AL+ Sbjct: 186 WLTYVSMDELLSTSDVISLHMPATKDSHHLINAKTIAQMKDGVYLVNTARGAVIDSQALL 245 Query: 358 EHLKANPMFRVGLDVFEDE-PYMKPG-------------LAEMKNAVVVPHIASASKWTR 495 + L + LD +E E PY+ L + + PHIA ++ Sbjct: 246 DSLDKGKIAGAALDAYEFEGPYIPKDNGNNPITDTVYARLVAHERIIYTPHIAFYTETAI 305 Query: 496 EGM 504 E M Sbjct: 306 ENM 308
>PTXD_PSEST (O69054) Phosphonate dehydrogenase (EC 1.20.1.1) (NAD-dependent| phosphite dehydrogenase) Length = 336 Score = 65.5 bits (158), Expect = 1e-10 Identities = 42/129 (32%), Positives = 64/129 (49%), Gaps = 8/129 (6%) Frame = +1 Query: 184 RASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEH 363 R + E+ +D I L L+ T HL+N E LA+++ A+LVN RG V+DE A++ Sbjct: 190 RQVACSELFASSDFILLALPLNADTQHLVNAELLALVRPGALLVNPCRGSVVDEAAVLAA 249 Query: 364 LKANPMFRVGLDVFEDEPYMK--------PGLAEMKNAVVVPHIASASKWTREGMATLAA 519 L+ + DVFE E + + P L N + PHI SA + R + AA Sbjct: 250 LERGQLGGYAADVFEMEDWARADRPRLIDPALLAHPNTLFTPHIGSAVRAVRLEIERCAA 309 Query: 520 LNVLGKIKG 546 N++ + G Sbjct: 310 QNIIQVLAG 318
>PDXB_WIGBR (Q8D2P6) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 65.1 bits (157), Expect = 2e-10 Identities = 39/104 (37%), Positives = 61/104 (58%), Gaps = 4/104 (3%) Frame = +1 Query: 184 RASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVA 351 + S+ E+++ +D+I+LH L + T+HLIN + L +K +L+N SRG VID + Sbjct: 156 KLKSLNEIVQNSDIITLHVPLTYSGKYPTWHLINKKILLDLKDNCILINTSRGSVIDNNS 215 Query: 352 LVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 483 L+ LK RV LDV+E+EP + L + + + PHIA S Sbjct: 216 LLNILKEGKPIRVVLDVWENEPLICSKLLSLID-IGTPHIAGHS 258
>Y2355_CORGL (P0C1E8) Hypothetical protein Cgl2355/cg2587 (EC 1.-.-.-)| Length = 304 Score = 64.7 bits (156), Expect = 2e-10 Identities = 42/111 (37%), Positives = 55/111 (49%), Gaps = 1/111 (0%) Frame = +1 Query: 199 EEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANP 378 E V EADV L L TY ++N E L MK AV+VN RGP+I+ LV+ L Sbjct: 175 EHVWAEADVFVLILPLTDATYQIVNAETLGKMKPSAVVVNVGRGPLINTDDLVDALNNGT 234 Query: 379 MFRVGLDVFEDEPYM-KPGLAEMKNAVVVPHIASASKWTREGMATLAALNV 528 + LDV + EP L EM N V+ PH A+ ++ R L N+ Sbjct: 235 IAGAALDVTDPEPLPDSHPLWEMDNVVITPHTANTNERIRALTGELTLRNI 285
>PDXB_SALTY (P60802) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 64.3 bits (155), Expect = 3e-10 Identities = 41/109 (37%), Positives = 61/109 (55%), Gaps = 4/109 (3%) Frame = +1 Query: 193 SMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 360 +++E+++EADV++ H L K T HL + + +K A+L+NA RGPV+D AL+ Sbjct: 160 TLDELVQEADVLTFHTPLYKDGPYKTLHLADETLIRRLKPGAILINACRGPVVDNAALLA 219 Query: 361 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 507 L A V LDV+E EP + L E + + HIA +T EG A Sbjct: 220 RLNAGQPLSVVLDVWEGEPDLNVALLEAVD-IGTSHIAG---YTLEGKA 264
>PDXB_SALTI (P60801) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 64.3 bits (155), Expect = 3e-10 Identities = 41/109 (37%), Positives = 61/109 (55%), Gaps = 4/109 (3%) Frame = +1 Query: 193 SMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 360 +++E+++EADV++ H L K T HL + + +K A+L+NA RGPV+D AL+ Sbjct: 160 TLDELVQEADVLTFHTPLYKDGPYKTLHLADETLIRRLKPGAILINACRGPVVDNAALLA 219 Query: 361 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 507 L A V LDV+E EP + L E + + HIA +T EG A Sbjct: 220 RLNAGQPLSVVLDVWEGEPDLNVALLEAVD-IGTSHIAG---YTLEGKA 264
>DHGY_HYPME (P36234) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-dependent| hydroxypyruvate reductase) (HPR) (GDH) (Hydroxypyruvate dehydrogenase) (Glyoxylate reductase) Length = 321 Score = 64.3 bits (155), Expect = 3e-10 Identities = 39/148 (26%), Positives = 70/148 (47%) Frame = +1 Query: 64 EGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPV 243 +GF M++ YFD ++++ ++ E S++ +L + SL+ Sbjct: 167 QGFDMDIDYFDTHRAS--------------SSDEASYQATFHDSLDSLLSVSQFFSLNAP 212 Query: 244 LDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYM 423 T + N + + + A++VN +RG ++D +V L+A + G DVF EP + Sbjct: 213 STPETRYFFNKATIKSLPQGAIVVNTARGDLVDNELVVAALEAGRLAYAGFDVFAGEPNI 272 Query: 424 KPGLAEMKNAVVVPHIASASKWTREGMA 507 G ++ N + PHI SA+ RE MA Sbjct: 273 NEGYYDLPNTFLFPHIGSAATQAREDMA 300
>SERA_SHIFL (P0A9T3) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 409 Score = 64.3 bits (155), Expect = 3e-10 Identities = 38/124 (30%), Positives = 69/124 (55%), Gaps = 6/124 (4%) Frame = +1 Query: 196 MEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN 375 + ++L +DV+SLH + +T +++ + +++MK ++L+NASRG V+D AL + L + Sbjct: 196 LSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASK 255 Query: 376 PMFRVGLDVFEDE------PYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGK 537 + +DVF E P+ P L E N ++ PHI +++ +E + L V GK Sbjct: 256 HLAGAAIDVFPTEPATNSDPFTSP-LCEFDNVLLTPHIGGSTQEAQENI----GLEVAGK 310 Query: 538 IKGY 549 + Y Sbjct: 311 LIKY 314
>SERA_ECOLI (P0A9T0) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 409 Score = 64.3 bits (155), Expect = 3e-10 Identities = 38/124 (30%), Positives = 69/124 (55%), Gaps = 6/124 (4%) Frame = +1 Query: 196 MEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN 375 + ++L +DV+SLH + +T +++ + +++MK ++L+NASRG V+D AL + L + Sbjct: 196 LSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASK 255 Query: 376 PMFRVGLDVFEDE------PYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGK 537 + +DVF E P+ P L E N ++ PHI +++ +E + L V GK Sbjct: 256 HLAGAAIDVFPTEPATNSDPFTSP-LCEFDNVLLTPHIGGSTQEAQENI----GLEVAGK 310 Query: 538 IKGY 549 + Y Sbjct: 311 LIKY 314
>SERA_ECOL6 (P0A9T1) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 409 Score = 64.3 bits (155), Expect = 3e-10 Identities = 38/124 (30%), Positives = 69/124 (55%), Gaps = 6/124 (4%) Frame = +1 Query: 196 MEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN 375 + ++L +DV+SLH + +T +++ + +++MK ++L+NASRG V+D AL + L + Sbjct: 196 LSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASK 255 Query: 376 PMFRVGLDVFEDE------PYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGK 537 + +DVF E P+ P L E N ++ PHI +++ +E + L V GK Sbjct: 256 HLAGAAIDVFPTEPATNSDPFTSP-LCEFDNVLLTPHIGGSTQEAQENI----GLEVAGK 310 Query: 538 IKGY 549 + Y Sbjct: 311 LIKY 314
>SERA_ECO57 (P0A9T2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 409 Score = 64.3 bits (155), Expect = 3e-10 Identities = 38/124 (30%), Positives = 69/124 (55%), Gaps = 6/124 (4%) Frame = +1 Query: 196 MEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN 375 + ++L +DV+SLH + +T +++ + +++MK ++L+NASRG V+D AL + L + Sbjct: 196 LSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASK 255 Query: 376 PMFRVGLDVFEDE------PYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGK 537 + +DVF E P+ P L E N ++ PHI +++ +E + L V GK Sbjct: 256 HLAGAAIDVFPTEPATNSDPFTSP-LCEFDNVLLTPHIGGSTQEAQENI----GLEVAGK 310 Query: 538 IKGY 549 + Y Sbjct: 311 LIKY 314
>LDHD_ECOLI (P52643) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH)| (Fermentative lactate dehydrogenase) Length = 329 Score = 64.3 bits (155), Expect = 3e-10 Identities = 39/119 (32%), Positives = 57/119 (47%) Frame = +1 Query: 58 MIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLH 237 +++GF M L+ FD Y S + Y + + E+DVISLH Sbjct: 162 ILKGFGMRLLAFDPYPSAAALELGVEY-----------------VDLPTLFSESDVISLH 204 Query: 238 PVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDE 414 L YHL+N MK ++VN SRG +ID A +E LK + +G+DV+E+E Sbjct: 205 CPLTPENYHLLNEAAFEQMKNGVMIVNTSRGALIDSQAAIEALKNQKIGSLGMDVYENE 263
>SERA_SCHPO (P87228) Putative D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95)| (3-PGDH) Length = 466 Score = 63.5 bits (153), Expect = 4e-10 Identities = 37/115 (32%), Positives = 59/115 (51%), Gaps = 13/115 (11%) Frame = +1 Query: 181 KRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 360 K+ SS+ E+L AD +SLH T ++I+ + A MK+ + L+NASRG V+D ALV+ Sbjct: 236 KQLSSLPELLHRADFVSLHVPASPETKNMISSKEFAAMKEGSYLINASRGTVVDIPALVD 295 Query: 361 HLKANPMFRVGLDVFEDEP-------------YMKPGLAEMKNAVVVPHIASASK 486 K+ + +DV+ EP L KN ++ PHI +++ Sbjct: 296 ASKSGKIAGAAIDVYPSEPAGNGKDKFVDSLNSWTSELTHCKNIILTPHIGGSTE 350
>PDXB_YERPS (Q668W7) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 375 Score = 63.5 bits (153), Expect = 4e-10 Identities = 42/109 (38%), Positives = 63/109 (57%), Gaps = 5/109 (4%) Frame = +1 Query: 196 MEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEH 363 +E+++READV++ H L+KT + H+ + E LA + +L+NA RG V+D AL+ Sbjct: 161 LEKLVREADVLTFHTPLNKTGAYQSLHMADDELLAALPDGRILINACRGAVVDNAALLRA 220 Query: 364 LKANPMFRVGLDVFEDEPYMK-PGLAEMKNAVVVPHIASASKWTREGMA 507 L+ V LDV+E EP + P LA + + PHIA +T EG A Sbjct: 221 LEKGKKLSVVLDVWEPEPDLSLPLLARVD--IGTPHIAG---YTLEGKA 264
>PDXB_YERPE (Q8D0U3) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 375 Score = 63.5 bits (153), Expect = 4e-10 Identities = 42/109 (38%), Positives = 63/109 (57%), Gaps = 5/109 (4%) Frame = +1 Query: 196 MEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEH 363 +E+++READV++ H L+KT + H+ + E LA + +L+NA RG V+D AL+ Sbjct: 161 LEKLVREADVLTFHTPLNKTGAYQSLHMADDELLAALPDGRILINACRGAVVDNAALLRA 220 Query: 364 LKANPMFRVGLDVFEDEPYMK-PGLAEMKNAVVVPHIASASKWTREGMA 507 L+ V LDV+E EP + P LA + + PHIA +T EG A Sbjct: 221 LEKGKKLSVVLDVWEPEPDLSLPLLARVD--IGTPHIAG---YTLEGKA 264
>DDH_HAEIN (P44501) 2-hydroxyacid dehydrogenase homolog (EC 1.1.1.-)| Length = 331 Score = 63.2 bits (152), Expect = 6e-10 Identities = 36/119 (30%), Positives = 67/119 (56%) Frame = +1 Query: 58 MIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLH 237 +++GF MN++ +D +++ +E+ GQ+++ ++E+ ++ VI+LH Sbjct: 162 ILKGFGMNILAYDPFKNPVVEELG---GQYVE--------------LDELYAKSHVITLH 204 Query: 238 PVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDE 414 YHL+N E A MK ++VN SRG +ID A ++ LK + +G+DV+E+E Sbjct: 205 CPATPENYHLLNCEAFAKMKDGVMIVNTSRGSLIDTQAAIDALKQRKIGALGMDVYENE 263
>PDXB_VIBPA (Q87MN8) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 377 Score = 63.2 bits (152), Expect = 6e-10 Identities = 35/97 (36%), Positives = 57/97 (58%), Gaps = 4/97 (4%) Frame = +1 Query: 196 MEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEH 363 + E++ ++D+I+LH + K T+HLI+ + L ++ + +L+NA+RGPV+D AL + Sbjct: 162 LAELIEQSDIITLHTPITKDGLHPTHHLIDEKVLNGLRGDQILINAARGPVVDNQALKQR 221 Query: 364 LKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIA 474 L F LDVFE EP + L + A PH+A Sbjct: 222 LMKQDGFTAALDVFEFEPEVDMELLPLL-AFATPHVA 257
>PDXB_SHEON (Q8ECR2) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 376 Score = 62.0 bits (149), Expect = 1e-09 Identities = 39/101 (38%), Positives = 54/101 (53%), Gaps = 4/101 (3%) Frame = +1 Query: 193 SMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 360 S+E +L+EAD+ISLH + +T T HL + RL +K L+N RG VID AL++ Sbjct: 161 SLETLLQEADIISLHVPITRTGEHKTLHLFDEARLMSLKANIWLINCCRGDVIDNQALIK 220 Query: 361 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 483 + ++ LDV+E EP P L PHIA S Sbjct: 221 VKQQRDDLKLVLDVWEGEPNPMPELVPFAE-FATPHIAGYS 260
>SERA_YEAST (P40054) D-3-phosphoglycerate dehydrogenase 1 (EC 1.1.1.95) (3-PGDH| 1) Length = 469 Score = 61.6 bits (148), Expect = 2e-09 Identities = 35/118 (29%), Positives = 64/118 (54%), Gaps = 14/118 (11%) Frame = +1 Query: 175 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 354 T ++ S+++E+L ++D ++LH T +++ + A MK A ++NASRG V+D +L Sbjct: 237 TARQVSTLDELLNKSDFVTLHVPATPETEKMLSAPQFAAMKDGAYVINASRGTVVDIPSL 296 Query: 355 VEHLKANPMFRVGLDVFEDEPYMKPG--------------LAEMKNAVVVPHIASASK 486 ++ +KAN + LDV+ EP K G L + N ++ PHI +++ Sbjct: 297 IQAVKANKIAGAALDVYPHEP-AKNGEGSFNDELNSWTSELVSLPNIILTPHIGGSTE 353
>SER33_YEAST (P40510) D-3-phosphoglycerate dehydrogenase 2 (EC 1.1.1.95) (3-PGDH| 2) Length = 469 Score = 61.6 bits (148), Expect = 2e-09 Identities = 35/118 (29%), Positives = 64/118 (54%), Gaps = 14/118 (11%) Frame = +1 Query: 175 TWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVAL 354 T ++ S+++E+L ++D ++LH T +++ + A MK A ++NASRG V+D +L Sbjct: 237 TARQVSTLDELLNKSDFVTLHVPATPETEKMLSAPQFAAMKDGAYVINASRGTVVDIPSL 296 Query: 355 VEHLKANPMFRVGLDVFEDEPYMKPG--------------LAEMKNAVVVPHIASASK 486 ++ +KAN + LDV+ EP K G L + N ++ PHI +++ Sbjct: 297 IQAVKANKIAGAALDVYPHEP-AKNGEGSFNDELNSWTSELVSLPNIILTPHIGGSTE 353
>YGDH_SCHPO (O94574) Putative 2-hydroxyacid dehydrogenase C1773.17c (EC| 1.-.-.-) Length = 340 Score = 61.6 bits (148), Expect = 2e-09 Identities = 32/100 (32%), Positives = 54/100 (54%) Frame = +1 Query: 193 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 372 S +E+L +DVIS++ L T+ LI+ + MK ++N +RG +I+E A ++ +K+ Sbjct: 207 SFDELLSSSDVISINCPLTPATHDLISTKEFEKMKDGVYIINTARGAIINEDAFIKAIKS 266 Query: 373 NPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWT 492 + R GLDVF +EP E + PH + +T Sbjct: 267 GKVARAGLDVFLNEPTPNKFWLECDKVTIQPHCGVYTNFT 306
>VANH_ENTFC (Q05709) D-specific alpha-keto acid dehydrogenase (EC 1.1.1.-)| (Vancomycin resistance protein vanH) Length = 322 Score = 61.2 bits (147), Expect = 2e-09 Identities = 39/130 (30%), Positives = 67/130 (51%), Gaps = 21/130 (16%) Frame = +1 Query: 148 LKANGEQPVTWKRASSME-------EVLREADVISLHPVLDKTTYHLINPERLAMMKKEA 306 L+ G + + + R+ S+E E+L+ +D+++LH L+ T+++I+ E++ MK+ A Sbjct: 165 LRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQRMKQGA 224 Query: 307 VLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEP-------YMKP-------GLAEM 444 L+N RGP++D LV+ L+ + LDV E E KP L M Sbjct: 225 FLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQFLLKLQRM 284 Query: 445 KNAVVVPHIA 474 N ++ PH A Sbjct: 285 PNVIITPHTA 294
>PDXB_ECOL6 (Q8FFH2) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 60.1 bits (144), Expect = 5e-09 Identities = 39/109 (35%), Positives = 60/109 (55%), Gaps = 4/109 (3%) Frame = +1 Query: 193 SMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 360 S++E+++ AD+++ H L K T HL + + + +K A+L+NA RG V+D AL+ Sbjct: 160 SLDELVQHADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALLT 219 Query: 361 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 507 L V LDV+E EP + L + K + PHIA +T EG A Sbjct: 220 CLNEGQKLSVVLDVWEGEPELNVELLK-KVDIGTPHIAG---YTLEGKA 264
>VANH_ENTFA (Q47748) D-specific alpha-keto acid dehydrogenase (EC 1.1.1.-)| (Vancomycin B-type resistance protein vanHB) Length = 323 Score = 59.7 bits (143), Expect = 6e-09 Identities = 34/108 (31%), Positives = 55/108 (50%), Gaps = 15/108 (13%) Frame = +1 Query: 196 MEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN 375 ++E+L+ +D+++LH L T HLI ++ MK+ A L+N RG ++D +LVE L + Sbjct: 189 LDELLKNSDIVTLHVPLCADTRHLIGQRQIGEMKQGAFLINTGRGALVDTGSLVEALGSG 248 Query: 376 PMFRVGLDVFE---------------DEPYMKPGLAEMKNAVVVPHIA 474 + LDV E D P++ L M N ++ PH A Sbjct: 249 KLGGAALDVLEGEDQFVYTDCSQKVLDHPFLSQ-LLRMPNVIITPHTA 295
>PDXB_SHIFL (Q83QR1) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 59.3 bits (142), Expect = 8e-09 Identities = 39/109 (35%), Positives = 59/109 (54%), Gaps = 4/109 (3%) Frame = +1 Query: 193 SMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 360 S++E+++ AD+++ H L K T HL + + + +K A+L+NA RG V+D AL+ Sbjct: 160 SLDELVQRADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALLT 219 Query: 361 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 507 L V LDV+E EP + L K + PHIA +T EG A Sbjct: 220 CLNEGQKLSVVLDVWEGEPELNVELL-TKVDIGTPHIAG---YTLEGKA 264
>PDXB_ERWCT (Q6D2N5) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 59.3 bits (142), Expect = 8e-09 Identities = 39/109 (35%), Positives = 59/109 (54%), Gaps = 4/109 (3%) Frame = +1 Query: 193 SMEEVLREADVISLHPVL----DKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 360 S+E ++R+AD+++LH L T+HL++ L +L+NA RGPV+D AL+E Sbjct: 160 SLETLVRDADILTLHTPLYLDGPYRTHHLVDATVLNAFADGRILINACRGPVVDNAALLE 219 Query: 361 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 507 L+ V LDV+E EP + L + + HIA +T EG A Sbjct: 220 ALQQGKKLSVILDVWEPEPGLSTDLLARVD-IGTAHIAG---YTLEGKA 264
>PDXB_ECO57 (Q8XCR0) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 59.3 bits (142), Expect = 8e-09 Identities = 39/109 (35%), Positives = 59/109 (54%), Gaps = 4/109 (3%) Frame = +1 Query: 193 SMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 360 S++E+++ AD+++ H L K T HL + + + +K A+L+NA RG V+D AL+ Sbjct: 160 SLDELVQRADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALLT 219 Query: 361 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 507 L V LDV+E EP + L K + PHIA +T EG A Sbjct: 220 CLNEGQKLSVVLDVWEGEPELNVELL-TKVDIGTPHIAG---YTLEGKA 264
>LDHD_STAES (Q8CN22) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 58.9 bits (141), Expect = 1e-08 Identities = 35/109 (32%), Positives = 58/109 (53%), Gaps = 15/109 (13%) Frame = +1 Query: 193 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 372 ++E+ +++AD+ISLH +K ++HL + +KK AVLVNA+RG VI+ L+E + Sbjct: 191 TVEDAIKDADIISLHVPANKDSFHLFDNNMFKNVKKGAVLVNAARGAVINTPDLIEAVNN 250 Query: 373 NPMFRVGLDVFE---------------DEPYMKPGLAEMKNAVVVPHIA 474 + +D +E D+P + L +N +V PHIA Sbjct: 251 GTLSGAAIDTYENEANYFTFDCSNQTIDDPILL-DLIRNENILVTPHIA 298
>LDHD_STAEQ (Q5HLA0) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 58.9 bits (141), Expect = 1e-08 Identities = 35/109 (32%), Positives = 58/109 (53%), Gaps = 15/109 (13%) Frame = +1 Query: 193 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 372 ++E+ +++AD+ISLH +K ++HL + +KK AVLVNA+RG VI+ L+E + Sbjct: 191 TVEDAIKDADIISLHVPANKDSFHLFDNNMFKNVKKGAVLVNAARGAVINTPDLIEAVNN 250 Query: 373 NPMFRVGLDVFE---------------DEPYMKPGLAEMKNAVVVPHIA 474 + +D +E D+P + L +N +V PHIA Sbjct: 251 GTLSGAAIDTYENEANYFTFDCSNQTIDDPILL-DLIRNENILVTPHIA 298
>LDHD_STAAR (Q6GDS2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 58.9 bits (141), Expect = 1e-08 Identities = 34/108 (31%), Positives = 56/108 (51%), Gaps = 14/108 (12%) Frame = +1 Query: 193 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 372 S++E +++AD+ISLH +K +YHL + +KK A+LVNA+RG VI+ L++ + Sbjct: 191 SVKEAIKDADIISLHVPANKESYHLFDKTMFDHVKKGAILVNAARGAVINTPDLIDAVND 250 Query: 373 NPMFRVGLDVFEDEPYMKPG--------------LAEMKNAVVVPHIA 474 + +D +E+E L E + +V PHIA Sbjct: 251 GTLLGAAIDTYENEAAYFTNDWTNKDIDDKTLLELIEHERILVTPHIA 298
>LDHD_LEUMC (P51011) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 331 Score = 58.9 bits (141), Expect = 1e-08 Identities = 42/153 (27%), Positives = 77/153 (50%), Gaps = 14/153 (9%) Frame = +1 Query: 58 MIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLH 237 +++GF +I +D Y + L+ A G ++ +++E+ +AD ISL+ Sbjct: 163 ILKGFGAKVIAYDKYPNAELQ----AEGLYV-------------DTLDELYAQADAISLY 205 Query: 238 PVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEP 417 +HLIN + +A MK V++NA+RG ++D A+++ L + + G+DV+E+E Sbjct: 206 VPGVPENHHLINADAIAKMKDGVVIMNAARGNLMDIDAIIDGLNSGKISDFGMDVYENEV 265 Query: 418 --YMKPGLAE------------MKNAVVVPHIA 474 MK GL + +N ++ PH A Sbjct: 266 ACSMKIGLVKNSPDAKIADLIARENVMITPHTA 298
>PDXB_COXBU (Q83AR8) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 366 Score = 58.5 bits (140), Expect = 1e-08 Identities = 42/97 (43%), Positives = 55/97 (56%), Gaps = 4/97 (4%) Frame = +1 Query: 208 LREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN 375 L D++ LH L KT TYHLI+ L M+K +VL+NA RG VID AL L+ + Sbjct: 165 LANVDLVCLHTPLVKTGNFPTYHLIDNRFLKMLKPGSVLLNAGRGAVIDNNAL---LQCD 221 Query: 376 PMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASK 486 + LDV+E+EP + L E K + PHIA SK Sbjct: 222 HVITC-LDVWENEPTVNLQLLE-KTTIATPHIAGYSK 256
>LDHD_STAAW (Q8NUT2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 57.8 bits (138), Expect = 2e-08 Identities = 34/108 (31%), Positives = 55/108 (50%), Gaps = 14/108 (12%) Frame = +1 Query: 193 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 372 S++E +++AD+ISLH +K +YHL + +KK A+LVNA+RG VI+ L+ + Sbjct: 191 SVKEAIKDADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVND 250 Query: 373 NPMFRVGLDVFEDEPYMKPG--------------LAEMKNAVVVPHIA 474 + +D +E+E L E + +V PHIA Sbjct: 251 GTLLGAAIDTYENEAAYFTNDWTNKDIDDKTLLELIEHERILVTPHIA 298
>LDHD_STAAU (P72357) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 57.8 bits (138), Expect = 2e-08 Identities = 34/108 (31%), Positives = 55/108 (50%), Gaps = 14/108 (12%) Frame = +1 Query: 193 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 372 S++E +++AD+ISLH +K +YHL + +KK A+LVNA+RG VI+ L+ + Sbjct: 191 SVKEAIKDADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVND 250 Query: 373 NPMFRVGLDVFEDEPYMKPG--------------LAEMKNAVVVPHIA 474 + +D +E+E L E + +V PHIA Sbjct: 251 GTLLGAAIDTYENEAAYFTNDWTNKDIDDKTLLELIEHERILVTPHIA 298
>LDHD_STAAS (Q6G6F1) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 57.8 bits (138), Expect = 2e-08 Identities = 34/108 (31%), Positives = 55/108 (50%), Gaps = 14/108 (12%) Frame = +1 Query: 193 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 372 S++E +++AD+ISLH +K +YHL + +KK A+LVNA+RG VI+ L+ + Sbjct: 191 SVKEAIKDADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVND 250 Query: 373 NPMFRVGLDVFEDEPYMKPG--------------LAEMKNAVVVPHIA 474 + +D +E+E L E + +V PHIA Sbjct: 251 GTLLGAAIDTYENEAAYFTNDWTNKDIDDKTLLELIEHERILVTPHIA 298
>LDHD_STAAN (P99116) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 57.8 bits (138), Expect = 2e-08 Identities = 34/108 (31%), Positives = 55/108 (50%), Gaps = 14/108 (12%) Frame = +1 Query: 193 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 372 S++E +++AD+ISLH +K +YHL + +KK A+LVNA+RG VI+ L+ + Sbjct: 191 SVKEAIKDADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVND 250 Query: 373 NPMFRVGLDVFEDEPYMKPG--------------LAEMKNAVVVPHIA 474 + +D +E+E L E + +V PHIA Sbjct: 251 GTLLGAAIDTYENEAAYFTNDWTNKDIDDKTLLELIEHERILVTPHIA 298
>LDHD_STAAM (P63940) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 57.8 bits (138), Expect = 2e-08 Identities = 34/108 (31%), Positives = 55/108 (50%), Gaps = 14/108 (12%) Frame = +1 Query: 193 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 372 S++E +++AD+ISLH +K +YHL + +KK A+LVNA+RG VI+ L+ + Sbjct: 191 SVKEAIKDADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVND 250 Query: 373 NPMFRVGLDVFEDEPYMKPG--------------LAEMKNAVVVPHIA 474 + +D +E+E L E + +V PHIA Sbjct: 251 GTLLGAAIDTYENEAAYFTNDWTNKDIDDKTLLELIEHERILVTPHIA 298
>LDHD_STAAC (Q5HD29) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 57.8 bits (138), Expect = 2e-08 Identities = 34/108 (31%), Positives = 55/108 (50%), Gaps = 14/108 (12%) Frame = +1 Query: 193 SMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKA 372 S++E +++AD+ISLH +K +YHL + +KK A+LVNA+RG VI+ L+ + Sbjct: 191 SVKEAIKDADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVND 250 Query: 373 NPMFRVGLDVFEDEPYMKPG--------------LAEMKNAVVVPHIA 474 + +D +E+E L E + +V PHIA Sbjct: 251 GTLLGAAIDTYENEAAYFTNDWTNKDIDDKTLLELIEHERILVTPHIA 298
>PDXB_PHOPR (Q6LNU2) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 391 Score = 57.8 bits (138), Expect = 2e-08 Identities = 39/113 (34%), Positives = 61/113 (53%), Gaps = 9/113 (7%) Frame = +1 Query: 163 EQPVTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRG 330 EQ ++ S+E + + DVI++H + K T+HLIN + ++ +A+L+NA+RG Sbjct: 151 EQEGDTRQFHSLEAIKAQCDVITVHTPITKDGEYPTHHLINEAFIDALQPDAILINAARG 210 Query: 331 PVIDEVALVEHLKAN-----PMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIA 474 PV D AL + L+ + LDVFE EP++ L + A PHIA Sbjct: 211 PVTDNQALKKALQLSQSGLGKKLTAVLDVFEFEPHVDLELLPLL-AFATPHIA 262
>LDHD_LACPL (Q88VJ2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH)| Length = 332 Score = 57.8 bits (138), Expect = 2e-08 Identities = 34/119 (28%), Positives = 62/119 (52%) Frame = +1 Query: 58 MIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLH 237 + +GF +I +D+Y++ LEK G ++ +++E+ +ADVI+LH Sbjct: 163 IFKGFGAKVIGYDVYRNAELEK----EGMYV-------------DTLDELYAQADVITLH 205 Query: 238 PVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDE 414 K YH++N + + MK A ++N +RG +ID L++ L + + LD +E E Sbjct: 206 VPALKDNYHMLNADAFSKMKDGAYILNFARGTLIDSEDLIKALDSGKVAGAALDTYEYE 264
>DHD2_LACPA (P17584) D-2-hydroxyisocaproate dehydrogenase (EC 1.1.1.-)| (D-HICDH) Length = 333 Score = 57.8 bits (138), Expect = 2e-08 Identities = 36/109 (33%), Positives = 61/109 (55%), Gaps = 15/109 (13%) Frame = +1 Query: 193 SMEEVLREADVISLH-PVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLK 369 S+E++ +++DVI LH P +++ T H+IN +MK A+++N +R +ID A++ +LK Sbjct: 190 SLEDLFKQSDVIDLHVPGIEQNT-HIINEAAFNLMKPGAIVINTARPNLIDTQAMLSNLK 248 Query: 370 ANPMFRVGLDVFEDEPYMKPGLAE--------------MKNAVVVPHIA 474 + + VG+D +E E LA+ M N V+ PHIA Sbjct: 249 SGKLAGVGIDTYEYETEDLLNLAKHGSFKDPLWDELLGMPNVVLSPHIA 297
>LDHD_STRP1 (Q99ZM2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 57.4 bits (137), Expect = 3e-08 Identities = 38/123 (30%), Positives = 62/123 (50%), Gaps = 1/123 (0%) Frame = +1 Query: 58 MIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLH 237 + +GF ++ +D+YQS K V Y + S+EE +++AD++SLH Sbjct: 163 IFKGFGCKVVGYDIYQSDAA-KAVLDYKE----------------SVEEAIKDADLVSLH 205 Query: 238 PVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDE- 414 HL N + KK A+L+N +RG VI+ L++ L A + G+D +E E Sbjct: 206 MPPTAENTHLFNSDLFKSFKKGAILMNMARGAVIETQDLLDALDAGLLSGAGIDTYEFEG 265 Query: 415 PYM 423 PY+ Sbjct: 266 PYI 268
>PDXB_ECOLI (P05459) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 57.0 bits (136), Expect = 4e-08 Identities = 38/109 (34%), Positives = 59/109 (54%), Gaps = 4/109 (3%) Frame = +1 Query: 193 SMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 360 S++E+++ AD+++ H L K T HL + + + +K A+L+NA RG V+D AL+ Sbjct: 160 SLDELVQRADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALLT 219 Query: 361 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 507 L V LDV+E EP + L + K + HIA +T EG A Sbjct: 220 CLNEGQKLSVVLDVWEGEPELNVELLK-KVDIGTSHIAG---YTLEGKA 264
>PDXB_SHEVI (Q56733) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| (Fragment) Length = 274 Score = 56.2 bits (134), Expect = 7e-08 Identities = 37/101 (36%), Positives = 55/101 (54%), Gaps = 4/101 (3%) Frame = +1 Query: 193 SMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 360 S++E++ DVISLH + KT T++L + RL +K L+N RG VID AL++ Sbjct: 47 SLDELIARCDVISLHVPIIKTGEHKTWYLFDETRLNSLKPGTWLLNCCRGEVIDNRALIK 106 Query: 361 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 483 + P ++ LDV+E EP L + + PHIA S Sbjct: 107 VKQQRPDIKLVLDVWEGEPNPMHELIPLVE-LATPHIAGYS 146
>PDXB_BACTN (Q8A2E4) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 348 Score = 55.8 bits (133), Expect = 9e-08 Identities = 35/102 (34%), Positives = 56/102 (54%), Gaps = 4/102 (3%) Frame = +1 Query: 190 SSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALV 357 +S+E++ E D+I+ H L K TYHL + ++++ V++N SRG VI+ AL+ Sbjct: 160 TSLEKIAEECDIITFHVPLYKEGKYKTYHLADGNFFRSLQRKPVVINTSRGEVIETNALL 219 Query: 358 EHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 483 E + + +DV+E EP + L E K + PHIA S Sbjct: 220 EAINNGIISDAVIDVWEHEPEINRELLE-KVLIGTPHIAGYS 260
>PDXB_SHESP (Q56731) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| (Fragment) Length = 274 Score = 55.5 bits (132), Expect = 1e-07 Identities = 37/101 (36%), Positives = 55/101 (54%), Gaps = 4/101 (3%) Frame = +1 Query: 193 SMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVE 360 S++E++ DVISLH + KT T++L + RL +K+ L+N RG VID AL++ Sbjct: 47 SLDELIACCDVISLHVPITKTGEHKTWYLFDEARLNSLKQGTWLLNCCRGEVIDNQALIK 106 Query: 361 HLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 483 P ++ LDV+E EP L + + PHIA S Sbjct: 107 VKLERPDIKLVLDVWEGEPNPMHELIPLVE-LATPHIAGYS 146
>FDH_NEUCR (Q07103) Formate dehydrogenase (EC 1.2.1.2) (NAD-dependent formate| dehydrogenase) (FDH) Length = 375 Score = 54.7 bits (130), Expect = 2e-07 Identities = 37/120 (30%), Positives = 64/120 (53%), Gaps = 6/120 (5%) Frame = +1 Query: 142 QFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 321 Q L A E + +R + +EE+L + DV++++ L + T L N E ++ MKK + LVN Sbjct: 198 QPLSAEKEAEIGCRRVADLEEMLAQCDVVTINCPLHEKTQGLFNKELISKMKKGSWLVNT 257 Query: 322 SRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKP-GLAEMKNA-----VVVPHIASAS 483 +RG ++ + + E LK+ + G DV+ +P + L KN +VPH++ S Sbjct: 258 ARGAIVVKEDVAEALKSGHLRGYGGDVWFPQPAPQDHPLRYAKNPFGGGNAMVPHMSGTS 317
>LDHD_LACPE (P26298) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 332 Score = 54.3 bits (129), Expect = 3e-07 Identities = 33/119 (27%), Positives = 61/119 (51%) Frame = +1 Query: 58 MIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLH 237 + +GF +I +D+Y++ LEK G ++ +++E+ +ADVI+LH Sbjct: 163 IFKGFGAKVIGYDVYRNAELEK----EGMYV-------------DTLDELYAQADVITLH 205 Query: 238 PVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDE 414 K YH++N + + MK A ++N +RG +ID L++ L + + L +E E Sbjct: 206 VPALKDNYHMLNADAFSKMKDGAYILNFARGTLIDSEDLIKALDSGKVAGAALVTYEYE 264
>LDHD_PEDAC (Q59642) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 331 Score = 53.5 bits (127), Expect = 5e-07 Identities = 39/166 (23%), Positives = 77/166 (46%), Gaps = 14/166 (8%) Frame = +1 Query: 70 FKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLD 249 F +I +D++++ LEK G ++ ++EE+ ++A+VI+LH Sbjct: 166 FGAKVIAYDVFRNPALEK----EGMYV-------------DTLEELYQQANVITLHVPAL 208 Query: 250 KTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFE------- 408 K YH+++ + M+ ++N +RG ++D AL++ L + + LD +E Sbjct: 209 KDNYHMLDEKAFGQMQDGTFILNFARGTLVDTPALLKALDSGKVAGAALDTYENEVGIFD 268 Query: 409 ----DEPYMKP---GLAEMKNAVVVPHIASASKWTREGMATLAALN 525 D+P P L +N ++ PH A ++ + M +A N Sbjct: 269 VDHGDQPIDDPVFNDLMSRRNVMITPHAAFYTRPAVKNMVQIALDN 314
>FDH_HORVU (Q9ZRI8) Formate dehydrogenase, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase) (FDH) Length = 377 Score = 53.5 bits (127), Expect = 5e-07 Identities = 40/151 (26%), Positives = 72/151 (47%), Gaps = 5/151 (3%) Frame = +1 Query: 46 YARMMIEG---FKMNLIYFDLYQ-STRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLR 213 Y R++++ F NL+Y D Q + LEK + A K ++ +L Sbjct: 201 YGRLLLQRLKPFNCNLLYHDRLQINPELEKEIGA---------------KFEEDLDAMLP 245 Query: 214 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 393 + DV+ ++ L + T + N E++A MKK ++VN +RG ++D A+ + + + G Sbjct: 246 KCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYG 305 Query: 394 LDVFEDEPYMKP-GLAEMKNAVVVPHIASAS 483 DV+ +P K M N + PHI+ + Sbjct: 306 GDVWFPQPAPKDHPWRYMPNHAMTPHISGTT 336
>FDH1_ORYSA (Q9SXP2) Formate dehydrogenase 1, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase 1) (FDH 1) Length = 376 Score = 53.1 bits (126), Expect = 6e-07 Identities = 40/143 (27%), Positives = 67/143 (46%), Gaps = 2/143 (1%) Frame = +1 Query: 61 IEGFKMNLIYFD-LYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLH 237 ++ F NL+Y D L LEK + A K ++ +L + DVI ++ Sbjct: 208 LKPFNCNLLYHDRLKIDPELEKEIGA---------------KYEEDLDAMLPKCDVIVIN 252 Query: 238 PVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEP 417 L + T + N ER+A MKK ++VN +RG ++D A+ + + + G DV+ +P Sbjct: 253 TPLTEKTRGMFNKERIAKMKKGVIIVNNARGAIMDTQAVADACSSGQVAGYGGDVWFPQP 312 Query: 418 YMKP-GLAEMKNAVVVPHIASAS 483 K M N + PHI+ + Sbjct: 313 APKDHPWRYMPNHAMTPHISGTT 335
>YP113_YEAST (Q02961) Putative 2-hydroxyacid dehydrogenase YPL113C (EC 1.-.-.-)| Length = 396 Score = 53.1 bits (126), Expect = 6e-07 Identities = 40/137 (29%), Positives = 67/137 (48%), Gaps = 1/137 (0%) Frame = +1 Query: 70 FKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLD 249 F M++ Y+ ++ ++K + Y ++ + P TWK A D+I L Sbjct: 240 FNMSIEYYK--RTGPVQKSLLDYNAKYHSDLDDPNTWKNA----------DLIILALPST 287 Query: 250 KTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFE-DEPYMK 426 +T ++IN + LA K +VN RG IDE L++ L++ + GLDVF+ +E +K Sbjct: 288 ASTNNIINRKSLAWCKDGVRIVNVGRGTCIDEDVLLDALESGKVASCGLDVFKNEETRVK 347 Query: 427 PGLAEMKNAVVVPHIAS 477 L + +PHI S Sbjct: 348 QELLRRWDVTALPHIGS 364
>LDHD_STRA5 (Q8E0N5) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 52.4 bits (124), Expect = 1e-06 Identities = 33/123 (26%), Positives = 59/123 (47%), Gaps = 1/123 (0%) Frame = +1 Query: 58 MIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLH 237 + +GF +I +D+Y + + + + +S+EE + EAD++SLH Sbjct: 163 IFKGFGCRVIGYDIYHNPMADGIL-----------------EYVNSVEEAVEEADLVSLH 205 Query: 238 PVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDE- 414 HL N + KK A+L+N +RG +++ L+E L + G+D +E E Sbjct: 206 MPPTAENTHLFNLDMFKQFKKGAILMNMARGALVETKDLLEALDQGLLEGAGIDTYEFEG 265 Query: 415 PYM 423 PY+ Sbjct: 266 PYI 268
>PDXB_BLOFL (Q7VRU9) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 372 Score = 51.6 bits (122), Expect = 2e-06 Identities = 33/108 (30%), Positives = 59/108 (54%), Gaps = 4/108 (3%) Frame = +1 Query: 172 VTWKRASSMEEVLREADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVI 339 ++WK S++ ++ ++D+++LH L T T+H+IN + L + ++L+N SRG V+ Sbjct: 157 MSWK---SLDILVSKSDILTLHVPLTYTGAYPTWHMINKDILDALPSNSILINTSRGAVV 213 Query: 340 DEVALVEHLKANPMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 483 + L+ L+ V LDV+E EP + L + + HIA S Sbjct: 214 NNDDLLAILRCGKKINVILDVWESEPKLSLPLLSYVD-IGTAHIAGYS 260
>LDHD_STRA3 (Q8E6A9) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 50.8 bits (120), Expect = 3e-06 Identities = 32/123 (26%), Positives = 59/123 (47%), Gaps = 1/123 (0%) Frame = +1 Query: 58 MIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLH 237 + +GF +I +D+Y + + + + +S+EE + +AD++SLH Sbjct: 163 IFKGFGCRVIGYDIYHNPMADGIL-----------------EYVNSVEEAVEKADLVSLH 205 Query: 238 PVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDE- 414 HL N + KK A+L+N +RG +++ L+E L + G+D +E E Sbjct: 206 MPPTAENTHLFNLDMFKQFKKGAILMNMARGALVETKDLLEALDQGLLEGAGIDTYEFEG 265 Query: 415 PYM 423 PY+ Sbjct: 266 PYI 268
>FDH_SOLTU (Q07511) Formate dehydrogenase, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase) (FDH) Length = 381 Score = 48.9 bits (115), Expect = 1e-05 Identities = 35/143 (24%), Positives = 68/143 (47%), Gaps = 2/143 (1%) Frame = +1 Query: 61 IEGFKMNLIYFD-LYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLH 237 ++ F NL+Y D L + LE + A K ++++L + D++ ++ Sbjct: 213 LKPFNCNLLYHDRLKMDSELENQIGA---------------KFEEDLDKMLSKCDIVVIN 257 Query: 238 PVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEP 417 L + T + + ER+A +KK ++VN +RG ++D A+V+ + + DV+ +P Sbjct: 258 TPLTEKTKGMFDKERIAKLKKGVLIVNNARGAIMDTQAVVDACNSGHIAGYSGDVWYPQP 317 Query: 418 YMKP-GLAEMKNAVVVPHIASAS 483 K M N + PHI+ + Sbjct: 318 APKDHPWRYMPNQAMTPHISGTT 340
>YGT5_YEAST (P53100) Putative 2-hydroxyacid dehydrogenase YGL185C (EC 1.-.-.-)| Length = 379 Score = 48.5 bits (114), Expect = 1e-05 Identities = 31/98 (31%), Positives = 46/98 (46%), Gaps = 1/98 (1%) Frame = +1 Query: 256 TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGL 435 T HLIN + L +LVN RG ++D A+ + L + +GLDVF EP + + Sbjct: 270 TEHLINRKFLEHCNPGLILVNLGRGKILDLRAVSDALVTGRINHLGLDVFNKEPEIDEKI 329 Query: 436 AEMKNAV-VVPHIASASKWTREGMATLAALNVLGKIKG 546 + PH+ SA+K E LA +L + G Sbjct: 330 RSSDRLTSITPHLGSATKDVFEQSCELALTRILRVVSG 367
>FDH2_ORYSA (Q67U69) Formate dehydrogenase 2, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase 2) (FDH 2) Length = 378 Score = 47.8 bits (112), Expect = 3e-05 Identities = 37/143 (25%), Positives = 65/143 (45%), Gaps = 2/143 (1%) Frame = +1 Query: 61 IEGFKMNLIYFDLYQ-STRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLH 237 ++ F NL+Y D + LEK + A K ++ +L + DV+ ++ Sbjct: 210 LKPFNCNLMYHDRVKIDPELEKEIGA---------------KYEEDLDAMLPKCDVVVIN 254 Query: 238 PVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEP 417 L + T + N ER+A MKK +VN +RG ++D A+ + + + G DV+ +P Sbjct: 255 MPLTEKTRGMFNKERIAKMKKGVTIVNNARGAIMDTQAVADACASGHVAGYGGDVWFPQP 314 Query: 418 YMKP-GLAEMKNAVVVPHIASAS 483 K M N + PH + + Sbjct: 315 APKDHPWRYMPNHAMTPHCSGTT 337
>FDH_ARATH (Q9S7E4) Formate dehydrogenase, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase) (FDH) Length = 384 Score = 47.0 bits (110), Expect = 4e-05 Identities = 36/143 (25%), Positives = 67/143 (46%), Gaps = 2/143 (1%) Frame = +1 Query: 61 IEGFKMNLIYFD-LYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLH 237 ++ F NL+Y D L + LEK A K + E+L + DVI ++ Sbjct: 216 LKPFGCNLLYHDRLQMAPELEKETGA---------------KFVEDLNEMLPKCDVIVIN 260 Query: 238 PVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEP 417 L + T + N E + +KK ++VN +RG +++ A+V+ +++ + DV++ +P Sbjct: 261 MPLTEKTRGMFNKELIGKLKKGVLIVNNARGAIMERQAVVDAVESGHIGGYSGDVWDPQP 320 Query: 418 YMKP-GLAEMKNAVVVPHIASAS 483 K M N + PH + + Sbjct: 321 APKDHPWRYMPNQAMTPHTSGTT 343
>FDH2_YEAST (Q08987) Formate dehydrogenase 2 (EC 1.2.1.2) (NAD-dependent| formate dehydrogenase 2) Length = 376 Score = 46.2 bits (108), Expect = 7e-05 Identities = 31/115 (26%), Positives = 58/115 (50%) Frame = +1 Query: 82 LIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTY 261 L+Y+D YQ E NG + +R +E+++ ++DV++++ L K + Sbjct: 193 LLYYD-YQELPAEAINRLNEASKLFNGRGDIV-QRVEKLEDMVAQSDVVTINCPLHKDSR 250 Query: 262 HLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMK 426 L N + ++ MK A LVN +RG + + E +K+ + G DV++ +P K Sbjct: 251 GLFNKKLISHMKDGAYLVNTARGAICVAEDVAEAVKSGKLAGYGGDVWDKQPAPK 305
>FDH1_YEAST (Q08911) Formate dehydrogenase 1 (EC 1.2.1.2) (NAD-dependent| formate dehydrogenase 1) Length = 376 Score = 46.2 bits (108), Expect = 7e-05 Identities = 31/115 (26%), Positives = 58/115 (50%) Frame = +1 Query: 82 LIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTY 261 L+Y+D YQ E NG + +R +E+++ ++DV++++ L K + Sbjct: 193 LLYYD-YQELPAEAINRLNEASKLFNGRGDIV-QRVEKLEDMVAQSDVVTINCPLHKDSR 250 Query: 262 HLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMK 426 L N + ++ MK A LVN +RG + + E +K+ + G DV++ +P K Sbjct: 251 GLFNKKLISHMKDGAYLVNTARGAICVAEDVAEAVKSGKLAGYGGDVWDKQPAPK 305
>FDH_PSESR (P33160) Formate dehydrogenase (EC 1.2.1.2) (NAD-dependent formate| dehydrogenase) (FDH) Length = 400 Score = 45.1 bits (105), Expect = 2e-04 Identities = 27/88 (30%), Positives = 47/88 (53%) Frame = +1 Query: 163 EQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVID 342 E +TW ++ E++ DV++L+ L T H+IN E L + K+ A +VN +RG + D Sbjct: 232 ELNLTWH--ATREDMYPVCDVVTLNCPLHPETEHMINDETLKLFKRGAYIVNTARGKLCD 289 Query: 343 EVALVEHLKANPMFRVGLDVFEDEPYMK 426 A+ L++ + DV+ +P K Sbjct: 290 RDAVARALESGRLAGYAGDVWFPQPAPK 317
>FDH_PICAN (P33677) Formate dehydrogenase (EC 1.2.1.2) (NAD-dependent formate| dehydrogenase) (FDH) Length = 361 Score = 43.9 bits (102), Expect = 4e-04 Identities = 27/95 (28%), Positives = 49/95 (51%) Frame = +1 Query: 142 QFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNA 321 Q L E+ V +R ++E++ +AD+++++ L + L+N E L KK A LVN Sbjct: 196 QSLSKEAEEKVGARRVHDIKELVAQADIVTINCPLHAGSKGLVNAELLKHFKKGAWLVNT 255 Query: 322 SRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMK 426 +RG + + +K+ + G DV+ +P K Sbjct: 256 ARGAICVAEDVAAAVKSGQLRGYGGDVWFPQPAPK 290
>FDH_EMENI (Q03134) Probable formate dehydrogenase (EC 1.2.1.2) (NAD-dependent| formate dehydrogenase) (FDH) Length = 377 Score = 42.0 bits (97), Expect = 0.001 Identities = 30/112 (26%), Positives = 55/112 (49%), Gaps = 17/112 (15%) Frame = +1 Query: 142 QFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMK-------- 297 Q L+ E+ + +R S+EE++ + DV++++ L + T L N E ++ MK Sbjct: 193 QPLRPEVEKEIGARRVDSLEEMVSQCDVVTINCPLHEKTRGLFNKELISKMKPGKSALLY 252 Query: 298 ---------KEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMK 426 K + LVN +RG ++ + + E LK+ + G DV+ +P K Sbjct: 253 LIIPMLMYHKGSWLVNTARGAIVVKEDVAEALKSGHLRGYGGDVWFPQPAPK 304
>YCDW_ECOLI (P75913) Putative 2-hydroxyacid dehydrogenase ycdW (EC 1.-.-.-)| Length = 325 Score = 32.3 bits (72), Expect = 1.1 Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 1/78 (1%) Frame = +1 Query: 256 TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPY-MKPG 432 T +IN + L + A L+N +RG + E L+ L + + LDVF EP + Sbjct: 217 TVGIINQQLLEKLPDGAYLLNLARGVHVVEDDLLAALDSGKVKGAMLDVFNREPLPPESP 276 Query: 433 LAEMKNAVVVPHIASASK 486 L + + PH+A+ ++ Sbjct: 277 LWQHPRVTITPHVAAITR 294
>FAT_DROME (P33450) Cadherin-related tumor suppressor precursor (Protein fat)| Length = 5147 Score = 31.6 bits (70), Expect = 1.9 Identities = 18/65 (27%), Positives = 33/65 (50%) Frame = +1 Query: 94 DLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLIN 273 ++ +T L++ T+ + +T RASS+ + +DV P D TTY++ Sbjct: 2546 EISTATTLDREETSVYHLTLMAQDSSITEPRASSVNLTISVSDVNDNIPKFDSTTYNVAV 2605 Query: 274 PERLA 288 PER++ Sbjct: 2606 PERIS 2610
>NIP7_YEAST (Q08962) 60S ribosome subunit biogenesis protein NIP7| Length = 181 Score = 31.2 bits (69), Expect = 2.4 Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 6/63 (9%) Frame = +1 Query: 418 YMKPGLAEMKNAVVVPHIASAS----KWTREGMATL--AALNVLGKIKGYPVWGNPNAVE 579 Y+ +A++ +V P++ S K+T+ G L +L VL K Y +W PN Sbjct: 46 YVPDHVAKLATSVARPNLMSLGICLGKFTKTGKFRLHITSLTVLAKHAKYKIWIKPNGEM 105 Query: 580 PFL 588 PFL Sbjct: 106 PFL 108
>APBA2_RAT (O35431) Amyloid beta A4 precursor protein-binding family A member| 2 (Neuron-specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta) Length = 750 Score = 30.8 bits (68), Expect = 3.2 Identities = 25/100 (25%), Positives = 41/100 (41%), Gaps = 8/100 (8%) Frame = +1 Query: 118 EKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMK 297 + F AY +FL+ANG P S +E +D+I+ + + H N E ++ Sbjct: 519 QAFSVAYQEFLRANGINP----EDLSQKEY---SDIINTQEMYNDDLIHFSNSENCKELQ 571 Query: 298 KE--------AVLVNASRGPVIDEVALVEHLKANPMFRVG 393 E V+V + G ++ V L + P R G Sbjct: 572 LEKHKGEILGVVVVESGWGSILPTVILANMMNGGPAARSG 611
>APBA2_MOUSE (P98084) Amyloid beta A4 precursor protein-binding family A member| 2 (Neuron-specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta) Length = 750 Score = 30.8 bits (68), Expect = 3.2 Identities = 25/100 (25%), Positives = 41/100 (41%), Gaps = 8/100 (8%) Frame = +1 Query: 118 EKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMK 297 + F AY +FL+ANG P S +E +D+I+ + + H N E ++ Sbjct: 519 QAFSVAYQEFLRANGINP----EDLSQKEY---SDIINTQEMYNDDLIHFSNSENCKELQ 571 Query: 298 KE--------AVLVNASRGPVIDEVALVEHLKANPMFRVG 393 E V+V + G ++ V L + P R G Sbjct: 572 LEKHKGEILGVVVVESGWGSILPTVILANMMNGGPAARSG 611
>APBA2_PONPY (Q5RD33) Amyloid beta A4 precursor protein-binding family A member| 2 Length = 749 Score = 30.8 bits (68), Expect = 3.2 Identities = 25/100 (25%), Positives = 41/100 (41%), Gaps = 8/100 (8%) Frame = +1 Query: 118 EKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMK 297 + F AY +FL+ANG P S +E +D+I+ + + H N E ++ Sbjct: 518 QAFSVAYQEFLRANGINP----EDLSQKEY---SDIINTQEMYNDDLIHFSNSENCKELQ 570 Query: 298 KE--------AVLVNASRGPVIDEVALVEHLKANPMFRVG 393 E V+V + G ++ V L + P R G Sbjct: 571 LEKHKGEILGVVVVESGWGSILPTVILANMMNGGPAARSG 610
>APBA2_HUMAN (Q99767) Amyloid beta A4 precursor protein-binding family A member| 2 (Neuron-specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta) Length = 749 Score = 30.8 bits (68), Expect = 3.2 Identities = 25/100 (25%), Positives = 41/100 (41%), Gaps = 8/100 (8%) Frame = +1 Query: 118 EKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDKTTYHLINPERLAMMK 297 + F AY +FL+ANG P S +E +D+I+ + + H N E ++ Sbjct: 518 QAFSVAYQEFLRANGINP----EDLSQKEY---SDIINTQEMYNDDLIHFSNSENCKELQ 570 Query: 298 KE--------AVLVNASRGPVIDEVALVEHLKANPMFRVG 393 E V+V + G ++ V L + P R G Sbjct: 571 LEKHKGEILGVVVVESGWGSILPTVILANMMNGGPAARSG 610
>NODX_RHILV (P08888) Nodulation protein 10 (Nodulation protein X) (Probable| sugar acetylase) Length = 367 Score = 30.0 bits (66), Expect = 5.4 Identities = 22/85 (25%), Positives = 37/85 (43%), Gaps = 7/85 (8%) Frame = -2 Query: 338 ITGPRLAFTSTASFFIIASRSGFIRWYVVLSSTGCRLITSASLRTSSMLEALFHVTGCSP 159 +T + +S ASFF+ S F +V ++ L+ + L + +L+ LF+ T Sbjct: 67 VTDSYIRSSSAASFFVKRSLRIFPALFVNIAVMELALLVTGGLNVTGILQYLFYFTVYIL 126 Query: 158 LAFRNW-------PYAVTNFSSRVD 105 A R W PY ++ F D Sbjct: 127 TAARIWAVYFTYEPYTMSGFYGASD 151
>WSC4_YEAST (P38739) Cell wall integrity and stress response component 4| precursor Length = 605 Score = 30.0 bits (66), Expect = 5.4 Identities = 35/144 (24%), Positives = 57/144 (39%) Frame = -2 Query: 545 PLILPSTFRAASVAIPSRVHLDADAM*GTTTAFFISASPGFM*GSSSKTSRPTRNMGLAL 366 PL ST S I S + TTT+ +S S SS+ T+ T + Sbjct: 161 PLTTASTSTTPSTDITSALP--------TTTSTKLSTSIPTSTTSSTSTTTSTSS----- 207 Query: 365 RCSTSATSSITGPRLAFTSTASFFIIASRSGFIRWYVVLSSTGCRLITSASLRTSSMLEA 186 STS T S+T TST S +I++ + +++ + TS + TS+ Sbjct: 208 --STSTTVSVTSSTSTTTSTTSSTLISTSTSSSSSSTPTTTSSAPISTSTTSSTSTSTST 265 Query: 185 LFHVTGCSPLAFRNWPYAVTNFSS 114 + +P + N T F++ Sbjct: 266 TSPTSSSAPTSSSNTTPTSTTFTT 289
>NUOL_BUCAI (P57262) NADH-quinone oxidoreductase chain L (EC 1.6.99.5) (NADH| dehydrogenase I, chain L) (NDH-1, chain L) Length = 614 Score = 29.6 bits (65), Expect = 7.1 Identities = 13/50 (26%), Positives = 24/50 (48%) Frame = -2 Query: 374 LALRCSTSATSSITGPRLAFTSTASFFIIASRSGFIRWYVVLSSTGCRLI 225 ++ R S + I L T +F+++ + +G++RWYV G I Sbjct: 555 ISKRLSADPLNKIINYFLKVTQIFNFYLLKTSNGYVRWYVASMILGINFI 604
>PYRB_BUCAI (P57450) Aspartate carbamoyltransferase catalytic chain (EC| 2.1.3.2) (Aspartate transcarbamylase) (ATCase) Length = 310 Score = 29.6 bits (65), Expect = 7.1 Identities = 24/104 (23%), Positives = 46/104 (44%), Gaps = 11/104 (10%) Frame = +1 Query: 70 FKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADVISLHPV-- 243 FK N YF + ++ ++ ++ + WKR +++EE++ E D++ + + Sbjct: 180 FKHNKFYFISPDALKMPNYIN------NMLDKKEIYWKRHNNIEEIISEIDILYMTRIQK 233 Query: 244 --LDKTTYHLINPERLAMMKKEAVLVNASRG-------PVIDEV 348 LD T Y + + + A+L NA P IDE+ Sbjct: 234 ERLDSTEY---ANAKSKFVLRAAILKNARNNMKILHPLPRIDEI 274
>YAAA_SCHPO (Q09801) Hypothetical protein C22G7.10 in chromosome I| Length = 344 Score = 29.3 bits (64), Expect = 9.3 Identities = 27/121 (22%), Positives = 48/121 (39%), Gaps = 22/121 (18%) Frame = +1 Query: 136 YGQFLKANGEQPVTWKRASSMEEVLREADVISLHPVLDK-------------TTYHLINP 276 YG+ ++ + VT A S E+ E+D + +++ T P Sbjct: 17 YGETIEERNDG-VTVSNAKSPEQASEESDDSDIEFIIETKPGERAEPLGGSIATLGSTRP 75 Query: 277 ERLAMMKKEAV---------LVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKP 429 ++K AV L A P +D + V + +F + L+ F+D+P+ KP Sbjct: 76 SAKPQVEKTAVEVKTTEPQDLSTAETAPKVD-IDAVPTIDGKNIFEIDLESFDDKPWRKP 134 Query: 430 G 432 G Sbjct: 135 G 135
>FIP1_MOUSE (Q9D824) Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1)| Length = 581 Score = 29.3 bits (64), Expect = 9.3 Identities = 11/19 (57%), Positives = 14/19 (73%) Frame = +1 Query: 376 PMFRVGLDVFEDEPYMKPG 432 P+ V LD FED+P+ KPG Sbjct: 150 PLLEVDLDSFEDKPWRKPG 168
>NUP82_YEAST (P40368) Nucleoporin NUP82 (Nuclear pore protein NUP82)| Length = 713 Score = 29.3 bits (64), Expect = 9.3 Identities = 20/66 (30%), Positives = 31/66 (46%) Frame = -2 Query: 371 ALRCSTSATSSITGPRLAFTSTASFFIIASRSGFIRWYVVLSSTGCRLITSASLRTSSML 192 AL ++ S+ PR F+S I+ + IRWY VL+ + L S + +L Sbjct: 9 ALPIFQASLSASQSPRYIFSSQNGTRIVFIQDNIIRWYNVLTDS---LYHSLNFSRHLVL 65 Query: 191 EALFHV 174 + FHV Sbjct: 66 DDTFHV 71
>CBID_SYNEL (Q8DKT8) Putative cobalt-precorrin-6A synthase [deacetylating] (EC| 2.1.1.-) Length = 367 Score = 29.3 bits (64), Expect = 9.3 Identities = 14/39 (35%), Positives = 20/39 (51%) Frame = -1 Query: 420 VRLILKNIEADTEHGVSLEVLHQCNLVDHRATARVHQHC 304 V LK +E H + + H + +D RATA +H HC Sbjct: 291 VEAALKFLERMVPHVLPEILSHIAHRIDQRATAYIHAHC 329
>FIP1_RAT (Q5U317) Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1)| Length = 536 Score = 29.3 bits (64), Expect = 9.3 Identities = 11/19 (57%), Positives = 14/19 (73%) Frame = +1 Query: 376 PMFRVGLDVFEDEPYMKPG 432 P+ V LD FED+P+ KPG Sbjct: 150 PLLEVDLDSFEDKPWRKPG 168
>FIP1_PONPY (Q5RAA7) Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1)| Length = 588 Score = 29.3 bits (64), Expect = 9.3 Identities = 11/19 (57%), Positives = 14/19 (73%) Frame = +1 Query: 376 PMFRVGLDVFEDEPYMKPG 432 P+ V LD FED+P+ KPG Sbjct: 136 PLLEVDLDSFEDKPWRKPG 154
>SYM_ANASP (Q8Z068) Methionyl-tRNA synthetase (EC 6.1.1.10) (Methionine--tRNA| ligase) (MetRS) Length = 530 Score = 29.3 bits (64), Expect = 9.3 Identities = 18/43 (41%), Positives = 22/43 (51%), Gaps = 4/43 (9%) Frame = -1 Query: 213 PEDLLHAGSPLPC----HGLLTVSFQELAICCDEFLEPCGLVQ 97 P LL AG PLP HG LT Q++ ++P GLVQ Sbjct: 281 PAMLLSAGLPLPDRVFGHGFLTKDGQKMGKSLGNTVDPVGLVQ 323
>FIP1_HUMAN (Q6UN15) Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1)| (Factor interacting with PAP) (hFip1) (Rearranged in hypereosinophilia) Length = 594 Score = 29.3 bits (64), Expect = 9.3 Identities = 11/19 (57%), Positives = 14/19 (73%) Frame = +1 Query: 376 PMFRVGLDVFEDEPYMKPG 432 P+ V LD FED+P+ KPG Sbjct: 151 PLLEVDLDSFEDKPWRKPG 169
>RGYR_THEMA (O51934) Reverse gyrase [Includes: Helicase (EC 3.6.1.-);| Topoisomerase (EC 5.99.1.3)] Length = 1104 Score = 29.3 bits (64), Expect = 9.3 Identities = 15/59 (25%), Positives = 30/59 (50%) Frame = +1 Query: 46 YARMMIEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREAD 222 YA+++ F+ +Y D Y+ R +F +LK E+ VT + +EE++ + + Sbjct: 1022 YAKIVEVLFRRGYVYEDKYKRVRPTRFGVMVYSYLKERYEKYVTEETTRRLEEIMDKVE 1080 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 86,941,549 Number of Sequences: 219361 Number of extensions: 1824279 Number of successful extensions: 5863 Number of sequences better than 10.0: 136 Number of HSP's better than 10.0 without gapping: 5660 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5822 length of database: 80,573,946 effective HSP length: 107 effective length of database: 57,102,319 effective search space used: 5367617986 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
