ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | baal16p18 |
|---|---|
| Clone Library Name | barley_pub |
>NTF3_TOBAC (Q40517) Mitogen-activated protein kinase homolog NTF3 (EC| 2.7.11.24) (P43) Length = 372 Score = 280 bits (716), Expect = 3e-75 Identities = 134/170 (78%), Positives = 145/170 (85%) Frame = +2 Query: 149 MAMMVDPPNGIGNHGKHYYTMWQTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAI 328 MA V+PPNGI GKHYY+MWQ++FEIDTKYVPIKPIGRGAYGIVCSS+N+ETNEKVAI Sbjct: 1 MATPVEPPNGIRTPGKHYYSMWQSLFEIDTKYVPIKPIGRGAYGIVCSSVNRETNEKVAI 60 Query: 329 KKINNVFDNRVDAXXXXXXXXXXXXXXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDL 508 KKINN F+NR+DA NVIALKD+MMPIHRRSFKDVYLV ELMDTDL Sbjct: 61 KKINNAFENRIDALRTLRELKLLRHLRHENVIALKDVMMPIHRRSFKDVYLVYELMDTDL 120 Query: 509 HQIVKSSQPLSNDHCQYFLFQLLRGLKYLHSAGILHRDLKPGNLLVNANC 658 HQI+KSSQ LSNDHCQYFLFQLLRGLKYLHSA ILHRDLKPGNLL+NANC Sbjct: 121 HQIIKSSQTLSNDHCQYFLFQLLRGLKYLHSANILHRDLKPGNLLINANC 170
>MPK1_ARATH (Q39021) Mitogen-activated protein kinase homolog 1 (EC 2.7.11.24)| (MAP kinase 1) (AtMPK1) Length = 370 Score = 277 bits (709), Expect = 2e-74 Identities = 130/170 (76%), Positives = 146/170 (85%) Frame = +2 Query: 149 MAMMVDPPNGIGNHGKHYYTMWQTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAI 328 MA +VDPPNGI N GKHY++MWQT+FEIDTKY+PIKPIGRGAYG+VCSS+N +TNEKVAI Sbjct: 1 MATLVDPPNGIRNEGKHYFSMWQTLFEIDTKYMPIKPIGRGAYGVVCSSVNSDTNEKVAI 60 Query: 329 KKINNVFDNRVDAXXXXXXXXXXXXXXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDL 508 KKI+NV++NR+DA NVIALKD+MMPIH+ SFKDVYLV ELMDTDL Sbjct: 61 KKIHNVYENRIDALRTLRELKLLRHLRHENVIALKDVMMPIHKMSFKDVYLVYELMDTDL 120 Query: 509 HQIVKSSQPLSNDHCQYFLFQLLRGLKYLHSAGILHRDLKPGNLLVNANC 658 HQI+KSSQ LSNDHCQYFLFQLLRGLKY+HSA ILHRDLKPGNLLVNANC Sbjct: 121 HQIIKSSQVLSNDHCQYFLFQLLRGLKYIHSANILHRDLKPGNLLVNANC 170
>MAPK_PETHY (Q40884) Mitogen-activated protein kinase homolog 1 (EC 2.7.11.24)| (PMEK1) Length = 384 Score = 277 bits (708), Expect = 2e-74 Identities = 133/170 (78%), Positives = 144/170 (84%) Frame = +2 Query: 149 MAMMVDPPNGIGNHGKHYYTMWQTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAI 328 MA V+PPNGI GKHYY+MWQ++FEIDTKYVPIKPIGRGAYGIVCSS+N+ETNEKVAI Sbjct: 1 MATPVEPPNGIRTPGKHYYSMWQSLFEIDTKYVPIKPIGRGAYGIVCSSVNRETNEKVAI 60 Query: 329 KKINNVFDNRVDAXXXXXXXXXXXXXXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDL 508 KKINN F+NR+DA NVIALKD+MMPI RRSFKDVYLV ELMDTDL Sbjct: 61 KKINNAFENRIDALRTLRELKLLRHLRHENVIALKDVMMPIQRRSFKDVYLVYELMDTDL 120 Query: 509 HQIVKSSQPLSNDHCQYFLFQLLRGLKYLHSAGILHRDLKPGNLLVNANC 658 HQI+KSSQ LSNDHCQYFLFQLLRGLKYLHSA ILHRDLKPGNLL+NANC Sbjct: 121 HQIIKSSQTLSNDHCQYFLFQLLRGLKYLHSANILHRDLKPGNLLINANC 170
>MPK7_ARATH (Q39027) Mitogen-activated protein kinase homolog 7 (EC 2.7.11.24)| (MAP kinase 7) (AtMPK7) Length = 368 Score = 274 bits (700), Expect = 2e-73 Identities = 131/170 (77%), Positives = 146/170 (85%) Frame = +2 Query: 149 MAMMVDPPNGIGNHGKHYYTMWQTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAI 328 MAM+V+PPNGI GKHYY+MWQT+FEIDTKYVPIKPIGRGAYG+VCSSIN+ETNE+VAI Sbjct: 1 MAMLVEPPNGIKQQGKHYYSMWQTLFEIDTKYVPIKPIGRGAYGVVCSSINRETNERVAI 60 Query: 329 KKINNVFDNRVDAXXXXXXXXXXXXXXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDL 508 KKI+NVF+NRVDA NVIALKD+M+P +R SFKDVYLV ELMDTDL Sbjct: 61 KKIHNVFENRVDALRTLRELKLLRHVRHENVIALKDVMLPANRSSFKDVYLVYELMDTDL 120 Query: 509 HQIVKSSQPLSNDHCQYFLFQLLRGLKYLHSAGILHRDLKPGNLLVNANC 658 HQI+KSSQ LS+DHC+YFLFQLLRGLKYLHSA ILHRDLKPGNLLVNANC Sbjct: 121 HQIIKSSQSLSDDHCKYFLFQLLRGLKYLHSANILHRDLKPGNLLVNANC 170
>MPK2_ARATH (Q39022) Mitogen-activated protein kinase homolog 2 (EC 2.7.11.24)| (MAP kinase 2) (AtMPK2) Length = 376 Score = 273 bits (698), Expect = 3e-73 Identities = 129/170 (75%), Positives = 145/170 (85%) Frame = +2 Query: 149 MAMMVDPPNGIGNHGKHYYTMWQTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAI 328 MA VDPPNGI N GKHY++MWQT+FEIDTKYVPIKPIGRGAYG+VCSS+N+E+NE+VAI Sbjct: 1 MATPVDPPNGIRNQGKHYFSMWQTLFEIDTKYVPIKPIGRGAYGVVCSSVNRESNERVAI 60 Query: 329 KKINNVFDNRVDAXXXXXXXXXXXXXXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDL 508 KKI+NVF+NR+DA NV+ALKD+MM H+RSFKDVYLV ELMDTDL Sbjct: 61 KKIHNVFENRIDALRTLRELKLLRHLRHENVVALKDVMMANHKRSFKDVYLVYELMDTDL 120 Query: 509 HQIVKSSQPLSNDHCQYFLFQLLRGLKYLHSAGILHRDLKPGNLLVNANC 658 HQI+KSSQ LSNDHCQYFLFQLLRGLKY+HSA ILHRDLKPGNLLVNANC Sbjct: 121 HQIIKSSQVLSNDHCQYFLFQLLRGLKYIHSANILHRDLKPGNLLVNANC 170
>MPK4_ARATH (Q39024) Mitogen-activated protein kinase homolog 4 (EC 2.7.11.24)| (MAP kinase 4) (AtMPK4) Length = 376 Score = 201 bits (512), Expect = 1e-51 Identities = 96/164 (58%), Positives = 122/164 (74%), Gaps = 3/164 (1%) Frame = +2 Query: 176 GIGNHGKHY--YTMWQTMFEIDTKYVP-IKPIGRGAYGIVCSSINQETNEKVAIKKINNV 346 G+ HG Y Y ++ +FE+ KYVP ++PIGRGAYGIVC++ N ET E+VAIKKI N Sbjct: 18 GVATHGGSYVQYNVYGNLFEVSRKYVPPLRPIGRGAYGIVCAATNSETGEEVAIKKIGNA 77 Query: 347 FDNRVDAXXXXXXXXXXXXXXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKS 526 FDN +DA NVIA+KDI+ P R +F DVY+V ELMDTDLHQI++S Sbjct: 78 FDNIIDAKRTLREIKLLKHMDHENVIAVKDIIKPPQRENFNDVYIVYELMDTDLHQIIRS 137 Query: 527 SQPLSNDHCQYFLFQLLRGLKYLHSAGILHRDLKPGNLLVNANC 658 +QPL++DHC++FL+QLLRGLKY+HSA +LHRDLKP NLL+NANC Sbjct: 138 NQPLTDDHCRFFLYQLLRGLKYVHSANVLHRDLKPSNLLLNANC 181
>MMK2_MEDSA (Q40353) Mitogen-activated protein kinase homolog MMK2 (EC| 2.7.11.24) Length = 371 Score = 199 bits (505), Expect = 8e-51 Identities = 92/164 (56%), Positives = 123/164 (75%), Gaps = 3/164 (1%) Frame = +2 Query: 176 GIGNHGKHY--YTMWQTMFEIDTKYVP-IKPIGRGAYGIVCSSINQETNEKVAIKKINNV 346 G+ HG Y Y ++ +FE+ KYVP I+ +GRGAYGIVC+++N ET E+VAIKKI N Sbjct: 12 GVPTHGGRYLQYNIYGNLFEVSRKYVPPIRSVGRGAYGIVCAAVNAETREEVAIKKIGNA 71 Query: 347 FDNRVDAXXXXXXXXXXXXXXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKS 526 FDNR+DA NV+++KDI+ P + +F VY+VSELMDTDLHQI++S Sbjct: 72 FDNRIDAKRTLREIKLLRHMDHENVMSIKDIIRPPQKENFNHVYIVSELMDTDLHQIIRS 131 Query: 527 SQPLSNDHCQYFLFQLLRGLKYLHSAGILHRDLKPGNLLVNANC 658 +QP+++DHC+YF++QLLRGLKY+HSA +LHRDLKP NLL+NANC Sbjct: 132 NQPMTDDHCRYFVYQLLRGLKYVHSANVLHRDLKPSNLLLNANC 175
>NTF6_TOBAC (Q40531) Mitogen-activated protein kinase homolog NTF6 (EC| 2.7.11.24) (P43) Length = 371 Score = 194 bits (493), Expect = 2e-49 Identities = 94/164 (57%), Positives = 117/164 (71%), Gaps = 3/164 (1%) Frame = +2 Query: 176 GIGNHGKHY--YTMWQTMFEIDTKYVP-IKPIGRGAYGIVCSSINQETNEKVAIKKINNV 346 GI H Y Y + FE+ +KY+P I+P+GRGAYG+VC + N ET E+VAIKKI N Sbjct: 13 GIPTHEGKYVEYNVLGNFFEVTSKYIPPIQPVGRGAYGMVCCATNSETKEEVAIKKIGNA 72 Query: 347 FDNRVDAXXXXXXXXXXXXXXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKS 526 F+NR+DA N+I +KDI+ P R F DVY+V ELMDTDLHQI++S Sbjct: 73 FENRIDAKRTLREIKLLSHMDHENIIKIKDIVRPPDREEFNDVYIVYELMDTDLHQIIRS 132 Query: 527 SQPLSNDHCQYFLFQLLRGLKYLHSAGILHRDLKPGNLLVNANC 658 SQ L++DHCQYFL+QLLRGLKY+HSA +LHRDLKP NLL+NANC Sbjct: 133 SQALTDDHCQYFLYQLLRGLKYVHSANVLHRDLKPSNLLLNANC 176
>MPK5_ARATH (Q39025) Mitogen-activated protein kinase homolog 5 (EC 2.7.11.24)| (MAP kinase 5) (AtMPK5) Length = 376 Score = 192 bits (489), Expect = 6e-49 Identities = 90/164 (54%), Positives = 120/164 (73%), Gaps = 3/164 (1%) Frame = +2 Query: 176 GIGNHGKHY--YTMWQTMFEIDTKYVP-IKPIGRGAYGIVCSSINQETNEKVAIKKINNV 346 G+ HG Y Y ++ +FE+ KYVP I+PIGRGAYG VC++++ ET+E++AIKKI Sbjct: 18 GVLVHGGRYFQYNVYGNLFEVSNKYVPPIRPIGRGAYGFVCAAVDSETHEEIAIKKIGKA 77 Query: 347 FDNRVDAXXXXXXXXXXXXXXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKS 526 FDN+VDA NV+ +KDI+ P + F DVY+V ELMDTDLHQI++S Sbjct: 78 FDNKVDAKRTLREIKLLRHLEHENVVVIKDIIRPPKKEDFVDVYIVFELMDTDLHQIIRS 137 Query: 527 SQPLSNDHCQYFLFQLLRGLKYLHSAGILHRDLKPGNLLVNANC 658 +Q L++DHCQYFL+Q+LRGLKY+HSA +LHRDLKP NLL+N+NC Sbjct: 138 NQSLNDDHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNSNC 181
>NTF4_TOBAC (Q40532) Mitogen-activated protein kinase homolog NTF4 (EC| 2.7.11.24) (P45) Length = 393 Score = 192 bits (489), Expect = 6e-49 Identities = 91/161 (56%), Positives = 118/161 (73%), Gaps = 3/161 (1%) Frame = +2 Query: 185 NHGKHY--YTMWQTMFEIDTKYVP-IKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDN 355 +HG + Y ++ +FE+ KY P I PIG+GAYGIVCS++N ETNE VAIKKI N FDN Sbjct: 38 SHGGRFIQYNIFGNIFEVTAKYKPPIMPIGKGAYGIVCSALNSETNEHVAIKKIANAFDN 97 Query: 356 RVDAXXXXXXXXXXXXXXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQP 535 ++DA N++A++DI+ P R +F DVY+ ELMDTDLHQI++S+Q Sbjct: 98 KIDAKRTLREIKLLRHMDHENIVAIRDIIPPPQREAFNDVYIAYELMDTDLHQIIRSNQG 157 Query: 536 LSNDHCQYFLFQLLRGLKYLHSAGILHRDLKPGNLLVNANC 658 LS +HCQYFL+Q+LRGLKY+HSA +LHRDLKP NLL+NANC Sbjct: 158 LSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANC 198
>MPK6_ARATH (Q39026) Mitogen-activated protein kinase homolog 6 (EC 2.7.11.24)| (MAP kinase 6) (AtMPK6) Length = 395 Score = 192 bits (487), Expect = 1e-48 Identities = 91/161 (56%), Positives = 118/161 (73%), Gaps = 3/161 (1%) Frame = +2 Query: 185 NHGKHY--YTMWQTMFEIDTKYVP-IKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDN 355 +HG + Y ++ +FE+ KY P I PIG+GAYGIVCS++N ETNE VAIKKI N FDN Sbjct: 41 SHGGRFIQYNIFGNIFEVTAKYKPPIMPIGKGAYGIVCSAMNSETNESVAIKKIANAFDN 100 Query: 356 RVDAXXXXXXXXXXXXXXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQP 535 ++DA N++A++DI+ P R +F DVY+ ELMDTDLHQI++S+Q Sbjct: 101 KIDAKRTLREIKLLRHMDHENIVAIRDIIPPPLRNAFNDVYIAYELMDTDLHQIIRSNQA 160 Query: 536 LSNDHCQYFLFQLLRGLKYLHSAGILHRDLKPGNLLVNANC 658 LS +HCQYFL+Q+LRGLKY+HSA +LHRDLKP NLL+NANC Sbjct: 161 LSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANC 201
>MAPK_PEA (Q06060) Mitogen-activated protein kinase homolog D5 (EC 2.7.11.24)| Length = 394 Score = 190 bits (483), Expect = 3e-48 Identities = 93/175 (53%), Positives = 122/175 (69%), Gaps = 3/175 (1%) Frame = +2 Query: 143 EKMAMMVDPPNGIGNHGKHY--YTMWQTMFEIDTKY-VPIKPIGRGAYGIVCSSINQETN 313 ++ AM ++ +HG + Y ++ +FE+ KY PI PIG+GAYGIVCS+ N ETN Sbjct: 26 QQAAMGIENIPATLSHGGRFIQYNIFGNIFEVTAKYRPPIMPIGKGAYGIVCSAHNSETN 85 Query: 314 EKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNVIALKDIMMPIHRRSFKDVYLVSEL 493 E VA+KKI N FDN++DA NV+A++DI+ P R F DVY+ EL Sbjct: 86 EHVAVKKIANAFDNKIDAKRTLREIKLVRHMDHENVVAIRDIVPPPQREVFNDVYIAYEL 145 Query: 494 MDTDLHQIVKSSQPLSNDHCQYFLFQLLRGLKYLHSAGILHRDLKPGNLLVNANC 658 MDTDLHQI++S+Q LS +HCQYFL+Q+LRGLKY+HSA +LHRDLKP NLL+NANC Sbjct: 146 MDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANC 200
>MMK1_MEDSA (Q07176) Mitogen-activated protein kinase homolog MMK1 (EC| 2.7.11.24) (MAP kinase MSK7) (MAP kinase ERK1) Length = 387 Score = 190 bits (482), Expect = 4e-48 Identities = 91/161 (56%), Positives = 116/161 (72%), Gaps = 3/161 (1%) Frame = +2 Query: 185 NHGKHY--YTMWQTMFEIDTKYVP-IKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDN 355 +HG + Y ++ +FE+ KY P I PIG+GAYGIVCS+ N ETNE VA+KKI N FDN Sbjct: 33 SHGGRFIQYNIFGNIFEVTAKYKPPIMPIGKGAYGIVCSAHNSETNEHVAVKKIANAFDN 92 Query: 356 RVDAXXXXXXXXXXXXXXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQP 535 ++DA NV+A++DI+ P R F DVY+ ELMDTDLHQI++S+Q Sbjct: 93 KIDAKRTLREIKLLRHMDHENVVAIRDIVPPPQREVFNDVYIAYELMDTDLHQIIRSNQA 152 Query: 536 LSNDHCQYFLFQLLRGLKYLHSAGILHRDLKPGNLLVNANC 658 LS +HCQYFL+Q+LRGLKY+HSA +LHRDLKP NLL+NANC Sbjct: 153 LSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANC 193
>MPK3_ARATH (Q39023) Mitogen-activated protein kinase homolog 3 (EC 2.7.11.24)| (MAP kinase 3) (AtMPK3) Length = 370 Score = 189 bits (480), Expect = 6e-48 Identities = 93/163 (57%), Positives = 119/163 (73%), Gaps = 3/163 (1%) Frame = +2 Query: 179 IGNHGKHY--YTMWQTMFEIDTKY-VPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVF 349 + HG + Y ++ ++FEI +KY PI PIGRGAYGIVCS ++ ETNE VA+KKI N F Sbjct: 14 VETHGGQFISYDIFGSLFEITSKYRPPIIPIGRGAYGIVCSVLDTETNELVAMKKIANAF 73 Query: 350 DNRVDAXXXXXXXXXXXXXXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSS 529 DN +DA N+IA++D++ P RR F DVY+ +ELMDTDLHQI++S+ Sbjct: 74 DNHMDAKRTLREIKLLRHLDHENIIAIRDVVPPPLRRQFSDVYISTELMDTDLHQIIRSN 133 Query: 530 QPLSNDHCQYFLFQLLRGLKYLHSAGILHRDLKPGNLLVNANC 658 Q LS +HCQYFL+QLLRGLKY+HSA I+HRDLKP NLL+NANC Sbjct: 134 QSLSEEHCQYFLYQLLRGLKYIHSANIIHRDLKPSNLLLNANC 176
>ERK1_DICDI (P42525) Extracellular signal-regulated kinase 1 (EC 2.7.11.24)| (ERK1) (MAP kinase 1) Length = 415 Score = 172 bits (435), Expect = 1e-42 Identities = 80/152 (52%), Positives = 107/152 (70%) Frame = +2 Query: 203 YTMWQTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXX 382 Y ++ + F + +Y +K IG GAYG+VCS+ + T EKVAIKKI+ FDN D Sbjct: 18 YFVYGSQFTVPRRYSIVKCIGHGAYGVVCSAKDNLTGEKVAIKKISKAFDNLKDTKRTLR 77 Query: 383 XXXXXXXXXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYF 562 N+I++KDI+ P + F+DVY+VSELMDTDLHQI+ S QPLS+DHCQYF Sbjct: 78 EIHLLRHFKHENLISIKDILKPNSKEQFEDVYIVSELMDTDLHQIITSPQPLSDDHCQYF 137 Query: 563 LFQLLRGLKYLHSAGILHRDLKPGNLLVNANC 658 ++Q+LRGLK++HSA +LHRDLKP NLL+N +C Sbjct: 138 VYQMLRGLKHIHSANVLHRDLKPSNLLINEDC 169
>MK07_HUMAN (Q13164) Mitogen-activated protein kinase 7 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase) Length = 815 Score = 147 bits (370), Expect = 4e-35 Identities = 74/146 (50%), Positives = 100/146 (68%), Gaps = 1/146 (0%) Frame = +2 Query: 224 FEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXX 403 F++ +Y I+ IG GAYG+V S+ + T ++VAIKKI N FD +A Sbjct: 48 FDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKH 107 Query: 404 XXXXNVIALKDIMMP-IHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLR 580 N+IA+KDI+ P + FK VY+V +LM++DLHQI+ SSQPL+ +H +YFL+QLLR Sbjct: 108 FKHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLR 167 Query: 581 GLKYLHSAGILHRDLKPGNLLVNANC 658 GLKY+HSA ++HRDLKP NLLVN NC Sbjct: 168 GLKYMHSAQVIHRDLKPSNLLVNENC 193
>MK07_MOUSE (Q9WVS8) Mitogen-activated protein kinase 7 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase) Length = 806 Score = 145 bits (367), Expect = 8e-35 Identities = 73/146 (50%), Positives = 100/146 (68%), Gaps = 1/146 (0%) Frame = +2 Query: 224 FEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXX 403 F++ +Y I+ IG GAYG+V S+ + T ++VAIKKI N FD +A Sbjct: 49 FDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKH 108 Query: 404 XXXXNVIALKDIMMP-IHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLR 580 N+IA+KDI+ P + F+ VY+V +LM++DLHQI+ SSQPL+ +H +YFL+QLLR Sbjct: 109 FKHDNIIAIKDILKPTVPYGEFRSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLR 168 Query: 581 GLKYLHSAGILHRDLKPGNLLVNANC 658 GLKY+HSA ++HRDLKP NLLVN NC Sbjct: 169 GLKYMHSAQVIHRDLKPSNLLVNENC 194
>NLK_MOUSE (O54949) Serine/threonine kinase NLK (EC 2.7.11.24) (Nemo-like| kinase) Length = 515 Score = 145 bits (366), Expect = 1e-34 Identities = 70/137 (51%), Positives = 95/137 (69%) Frame = +2 Query: 248 PIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNVIA 427 P +PIG GA+G+V S + ++VA+KK+ NVF N V NV++ Sbjct: 128 PDRPIGYGAFGVVWSVTDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDNVLS 187 Query: 428 LKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLRGLKYLHSAG 607 DI+ P H F+++Y+V+ELM +DLH+I+ S QPLS+DH + FL+Q+LRGLKYLHSAG Sbjct: 188 ALDILQPPHIDYFEEIYVVTELMQSDLHKIIVSPQPLSSDHVKVFLYQILRGLKYLHSAG 247 Query: 608 ILHRDLKPGNLLVNANC 658 ILHRD+KPGNLLVN+NC Sbjct: 248 ILHRDIKPGNLLVNSNC 264
>NLK_HUMAN (Q9UBE8) Serine/threonine kinase NLK (EC 2.7.11.24) (Nemo-like| kinase) (LAK1 protein) Length = 515 Score = 145 bits (366), Expect = 1e-34 Identities = 70/137 (51%), Positives = 95/137 (69%) Frame = +2 Query: 248 PIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNVIA 427 P +PIG GA+G+V S + ++VA+KK+ NVF N V NV++ Sbjct: 128 PDRPIGYGAFGVVWSVTDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDNVLS 187 Query: 428 LKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLRGLKYLHSAG 607 DI+ P H F+++Y+V+ELM +DLH+I+ S QPLS+DH + FL+Q+LRGLKYLHSAG Sbjct: 188 ALDILQPPHIDYFEEIYVVTELMQSDLHKIIVSPQPLSSDHVKVFLYQILRGLKYLHSAG 247 Query: 608 ILHRDLKPGNLLVNANC 658 ILHRD+KPGNLLVN+NC Sbjct: 248 ILHRDIKPGNLLVNSNC 264
>SPK1_SCHPO (P27638) Mitogen-activated protein kinase spk1 (EC 2.7.11.24) (MAP| kinase spk1) (MAPK) Length = 372 Score = 140 bits (352), Expect = 4e-33 Identities = 68/145 (46%), Positives = 102/145 (70%) Frame = +2 Query: 224 FEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXX 403 FE+ +Y I IG+GAYG+VC+++++ + KVA+KKI+ F++ V Sbjct: 33 FELPEEYEMINLIGQGAYGVVCAALHKPSGLKVAVKKIHP-FNHPVFCLRTLREIKLLRH 91 Query: 404 XXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLRG 583 N+I++ DI+ P + +DVY+V ELM+TDL+++++S QPLS+DHCQYF +Q+LR Sbjct: 92 FRHENIISILDILPPPSYQELEDVYIVQELMETDLYRVIRS-QPLSDDHCQYFTYQILRA 150 Query: 584 LKYLHSAGILHRDLKPGNLLVNANC 658 LK +HSAG++HRDLKP NLL+NANC Sbjct: 151 LKAMHSAGVVHRDLKPSNLLLNANC 175
>MAPK_FUSSO (Q00859) Mitogen-activated protein kinase (EC 2.7.11.24) (FsMAPK)| Length = 355 Score = 138 bits (348), Expect = 1e-32 Identities = 71/165 (43%), Positives = 103/165 (62%) Frame = +2 Query: 164 DPPNGIGNHGKHYYTMWQTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINN 343 +PPN G+ + F + +Y +G GAYG+VCS+I++ + +KVAIKKI Sbjct: 5 NPPNPTGSR--------KISFNVSEQYDIQDVVGEGAYGVVCSAIHKPSGQKVAIKKITP 56 Query: 344 VFDNRVDAXXXXXXXXXXXXXXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVK 523 FD+ + N+I++ DI P + SF +VYL+ ELM+TD+H+ ++ Sbjct: 57 -FDHSMFCLRTLREMKLLRYFNHENIISILDIQKPRNYESFNEVYLIQELMETDMHRAIR 115 Query: 524 SSQPLSNDHCQYFLFQLLRGLKYLHSAGILHRDLKPGNLLVNANC 658 + Q LS+DHCQYF++Q LR LK +HSA +LHRDLKP NLL+NANC Sbjct: 116 T-QDLSDDHCQYFIYQTLRALKAMHSANVLHRDLKPSNLLLNANC 159
>STY1_SCHPO (Q09892) Mitogen-activated protein kinase sty1 (EC 2.7.11.24) (MAP| kinase sty1) (MAP kinase spc1) Length = 349 Score = 135 bits (341), Expect = 8e-32 Identities = 68/147 (46%), Positives = 96/147 (65%) Frame = +2 Query: 218 TMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXX 397 T FEI T+Y ++PIG GA+G+VCS+ +Q T VA+KKI F V A Sbjct: 12 TCFEITTRYSDLQPIGMGAFGLVCSAKDQLTGMNVAVKKIMKPFSTPVLAKRTYRELKLL 71 Query: 398 XXXXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLL 577 N+I+L DI + F+D+Y V+EL+ TDLH+++ +S+PL QYFL+Q+L Sbjct: 72 KHLRHENIISLSDIFIS----PFEDIYFVTELLGTDLHRLL-TSRPLETQFIQYFLYQIL 126 Query: 578 RGLKYLHSAGILHRDLKPGNLLVNANC 658 RGLK++HSAG++HRDLKP N+L+N NC Sbjct: 127 RGLKFVHSAGVIHRDLKPSNILINENC 153
>ERK1_CANAL (P28869) Extracellular signal-regulated kinase 1 (EC 2.7.11.24)| (ERK1) (MAP kinase 1) (MAPK 1) Length = 417 Score = 134 bits (337), Expect = 2e-31 Identities = 66/148 (44%), Positives = 97/148 (65%) Frame = +2 Query: 215 QTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXX 394 Q F + Y ++ +G GAYGIVCS+I++ + +KVAIKKI F+ + Sbjct: 59 QVSFNVSDHYQILEIVGEGAYGIVCSAIHKPSQQKVAIKKIEP-FERSMLCLRTLRELKL 117 Query: 395 XXXXXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQL 574 N+I++ I PI+ SF ++YL+ ELM+TDLH+++++ Q LS+DH QYF++Q Sbjct: 118 LKHFNHENIISILAIQRPINYESFNEIYLIQELMETDLHRVIRT-QNLSDDHIQYFIYQT 176 Query: 575 LRGLKYLHSAGILHRDLKPGNLLVNANC 658 LR LK +HSA +LHRDLKP NLL+N+NC Sbjct: 177 LRALKAMHSANVLHRDLKPSNLLLNSNC 204
>HOG1_ASHGO (Q750A9) Mitogen-activated protein kinase HOG1 (EC 2.7.11.24) (MAP| kinase HOG1) Length = 447 Score = 134 bits (336), Expect = 3e-31 Identities = 65/147 (44%), Positives = 94/147 (63%) Frame = +2 Query: 218 TMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXX 397 T+FEI +Y + P+G GA+G+VCS+++ T + VAIKKI F V A Sbjct: 15 TVFEITNRYADLNPVGMGAFGLVCSAVDTYTQQPVAIKKIMKPFSTAVLAKRTYRELKLL 74 Query: 398 XXXXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLL 577 N+I L+DI + +D+Y V+EL TDLH+++++ +PL QYFL+Q+L Sbjct: 75 KHLRHENLICLEDIFLS----PLEDIYFVTELQGTDLHRLLQT-RPLEKQFLQYFLYQIL 129 Query: 578 RGLKYLHSAGILHRDLKPGNLLVNANC 658 RGLKY+HSAG++HRDLKP N+L+N NC Sbjct: 130 RGLKYVHSAGVIHRDLKPSNILINENC 156
>MK14A_CYPCA (Q90336) Mitogen-activated protein kinase 14a (EC 2.7.11.24)| (Mitogen-activated protein kinase p38a) (MAP kinase p38a) (cp38a) Length = 361 Score = 132 bits (331), Expect = 1e-30 Identities = 67/155 (43%), Positives = 96/155 (61%), Gaps = 1/155 (0%) Frame = +2 Query: 197 HYYTMWQTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXX 376 H + +T++E+ +Y + P+G GAYG VCS+ +++T KVA+KK++ F + + A Sbjct: 10 HRQEVNKTIWEVPVRYQNLSPVGSGAYGTVCSAYDEKTGLKVAVKKLSRPFQSIIHAKRT 69 Query: 377 XXXXXXXXXXXXXNVIALKDIMMPIHR-RSFKDVYLVSELMDTDLHQIVKSSQPLSNDHC 553 NVI L D+ P F DVYLV+ LM DL+ IVK Q L++DH Sbjct: 70 YRELRLLKHMKHENVIGLLDVFTPATSLEEFNDVYLVTHLMGADLNNIVKC-QKLTDDHV 128 Query: 554 QYFLFQLLRGLKYLHSAGILHRDLKPGNLLVNANC 658 Q+ ++Q+LRGLKY+HSA I+HRDLKP NL VN +C Sbjct: 129 QFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDC 163
>HOG1_DEBHA (Q9UV50) Mitogen-activated protein kinase HOG1 (EC 2.7.11.24) (MAP| kinase HOG1) Length = 387 Score = 131 bits (330), Expect = 2e-30 Identities = 65/147 (44%), Positives = 93/147 (63%) Frame = +2 Query: 218 TMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXX 397 T+FEI +Y + P+G GA+G+VCS+I++ T + VA+KKI F V A Sbjct: 15 TVFEITNRYTDLNPVGMGAFGLVCSAIDKLTGQNVAVKKIMKPFLTSVLAKRTYRELKLL 74 Query: 398 XXXXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLL 577 N+I L DI + +D+Y V+EL TDLH+++ +S+PL QYF +Q+L Sbjct: 75 KHLRHENLITLDDIFLS----PLEDIYFVTELQGTDLHRLL-TSRPLEKQFIQYFTYQIL 129 Query: 578 RGLKYLHSAGILHRDLKPGNLLVNANC 658 RGLKY+HSAG++HRDLKP N+L+N NC Sbjct: 130 RGLKYVHSAGVIHRDLKPSNILINENC 156
>MK14_XENLA (P47812) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated Mitogen-activated protein kinase 2) (MAP kinase 2) (MPK2) Length = 361 Score = 131 bits (330), Expect = 2e-30 Identities = 66/149 (44%), Positives = 93/149 (62%), Gaps = 1/149 (0%) Frame = +2 Query: 215 QTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXX 394 +T++E+ +Y + P+G GAYG VCSS + T ++A+KK++ F + + A Sbjct: 16 KTLWEVPDRYQNLTPVGSGAYGSVCSSFDTRTALRIAVKKLSRPFQSIIHAKRTYRELRL 75 Query: 395 XXXXXXXNVIALKDIMMPIHR-RSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQ 571 NVI L D+ P F DVYLV+ LM DL+ IVK Q L++DH Q+ ++Q Sbjct: 76 LKHMKHENVIGLLDVFSPAKSFEEFNDVYLVTHLMGADLNNIVKC-QKLTDDHVQFLIYQ 134 Query: 572 LLRGLKYLHSAGILHRDLKPGNLLVNANC 658 +LRGLKY+HSAGI+HRDLKP NL VN +C Sbjct: 135 ILRGLKYIHSAGIIHRDLKPSNLAVNEDC 163
>HOG1_CANAL (Q92207) Mitogen-activated protein kinase HOG1 (EC 2.7.11.24) (MAP| kinase HOG1) Length = 377 Score = 131 bits (330), Expect = 2e-30 Identities = 62/147 (42%), Positives = 93/147 (63%) Frame = +2 Query: 218 TMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXX 397 T+FEI +Y + P+G GA+G+VCS++++ T + VA+KK+ F V A Sbjct: 15 TVFEITNRYTELNPVGMGAFGLVCSAVDRLTGQNVAVKKVMKPFSTSVLAKRTYRELKLL 74 Query: 398 XXXXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLL 577 N+I L DI + +D+Y V+EL TDLH+++ +S+PL QYF +Q++ Sbjct: 75 KHLKHENLITLDDIFIS----PLEDIYFVNELQGTDLHRLL-NSRPLEKQFIQYFTYQIM 129 Query: 578 RGLKYLHSAGILHRDLKPGNLLVNANC 658 RGLKY+HSAG++HRDLKP N+L+N NC Sbjct: 130 RGLKYIHSAGVIHRDLKPSNILINENC 156
>HOG1_YEAST (P32485) Mitogen-activated protein kinase HOG1 (EC 2.7.11.24) (MAP| kinase HOG1) (Osmosensing protein HOG1) Length = 435 Score = 131 bits (329), Expect = 2e-30 Identities = 65/147 (44%), Positives = 94/147 (63%) Frame = +2 Query: 218 TMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXX 397 T+FEI +Y + P+G GA+G+VCS+ + T++ VAIKKI F V A Sbjct: 15 TVFEITNRYNDLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTYRELKLL 74 Query: 398 XXXXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLL 577 N+I L+DI + +D+Y V+EL TDLH+++++ +PL QYFL+Q+L Sbjct: 75 KHLRHENLICLQDIFLS----PLEDIYFVTELQGTDLHRLLQT-RPLEKQFVQYFLYQIL 129 Query: 578 RGLKYLHSAGILHRDLKPGNLLVNANC 658 RGLKY+HSAG++HRDLKP N+L+N NC Sbjct: 130 RGLKYVHSAGVIHRDLKPSNILINENC 156
>MK14A_BRARE (Q9DGE2) Mitogen-activated protein kinase 14a (EC 2.7.11.24)| (Mitogen-activated protein kinase p38a) (MAP kinase p38a) (zp38a) Length = 361 Score = 130 bits (328), Expect = 3e-30 Identities = 66/149 (44%), Positives = 94/149 (63%), Gaps = 1/149 (0%) Frame = +2 Query: 215 QTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXX 394 +T++E+ +Y + P+G GAYG VCS+ + +T KVA+KK++ F + + A Sbjct: 16 KTIWEVPVQYQNLSPVGSGAYGSVCSAFDAKTGFKVAVKKLSRPFQSIIHAKRTYRELRL 75 Query: 395 XXXXXXXNVIALKDIMMPIHR-RSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQ 571 NVI L D+ P + F DVYLV+ LM DL+ IVK Q L++DH Q+ ++Q Sbjct: 76 LKHMRHENVIGLLDVFTPATSLKEFNDVYLVTHLMGADLNNIVKC-QKLTDDHVQFLIYQ 134 Query: 572 LLRGLKYLHSAGILHRDLKPGNLLVNANC 658 +LRGLKY+HSA I+HRDLKP NL VN +C Sbjct: 135 ILRGLKYIHSADIIHRDLKPSNLAVNEDC 163
>HOG1_CANGA (Q6FIU2) Mitogen-activated protein kinase HOG1 (EC 2.7.11.24) (MAP| kinase HOG1) Length = 447 Score = 130 bits (327), Expect = 3e-30 Identities = 65/147 (44%), Positives = 94/147 (63%) Frame = +2 Query: 218 TMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXX 397 T+FEI +Y + P+G GA+G+VCS+ + TN++VAIKKI F V A Sbjct: 15 TVFEITNRYSDLNPVGMGAFGLVCSATDTLTNQQVAIKKIMKPFATAVLAKRTYRELKLL 74 Query: 398 XXXXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLL 577 N+I L+DI + +D+Y V+EL TDLH+++++ +PL QYF +Q+L Sbjct: 75 KHLRHENLICLQDIFLS----PLEDIYFVTELQGTDLHRLLQT-RPLEKQFVQYFHYQIL 129 Query: 578 RGLKYLHSAGILHRDLKPGNLLVNANC 658 RGLKY+HSAG++HRDLKP N+L+N NC Sbjct: 130 RGLKYVHSAGVVHRDLKPSNILINENC 156
>HOG1_ZYGRO (O93982) Mitogen-activated protein kinase HOG1 (EC 2.7.11.24) (MAP| kinase HOG1) Length = 380 Score = 130 bits (326), Expect = 5e-30 Identities = 64/147 (43%), Positives = 92/147 (62%) Frame = +2 Query: 218 TMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXX 397 T+FEI +Y + P+G GA+G+VCS+ + + VAIKKI F V A Sbjct: 15 TVFEITNRYTDLNPVGMGAFGLVCSATDTLAGQPVAIKKIMKPFSTAVLAKRTYRELKLL 74 Query: 398 XXXXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLL 577 N+I L+DI + +D+Y V+EL TDLH+++++ +PL QYFL+Q+L Sbjct: 75 KHLRHENLICLQDIFLS----PLEDIYFVTELQGTDLHRLLQT-RPLEKQFVQYFLYQIL 129 Query: 578 RGLKYLHSAGILHRDLKPGNLLVNANC 658 RGLKY+HSAG++HRDLKP N+L+N NC Sbjct: 130 RGLKYVHSAGVIHRDLKPSNILINENC 156
>MK14_RAT (P70618) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (CRK1) Length = 359 Score = 129 bits (325), Expect = 6e-30 Identities = 64/149 (42%), Positives = 93/149 (62%), Gaps = 1/149 (0%) Frame = +2 Query: 215 QTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXX 394 +T++E+ +Y + P+G GAYG VC++ + +T +VA+KK++ F + + A Sbjct: 14 KTVWEVPERYQNLSPVGSGAYGSVCAAFDTKTGHRVAVKKLSRPFQSIIHAKRTYRELRL 73 Query: 395 XXXXXXXNVIALKDIMMPIHR-RSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQ 571 NVI L D+ P F DVYLV+ LM DL+ IVK Q L++DH Q+ ++Q Sbjct: 74 LKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKC-QKLTDDHVQFLIYQ 132 Query: 572 LLRGLKYLHSAGILHRDLKPGNLLVNANC 658 +LRGLKY+HSA I+HRDLKP NL VN +C Sbjct: 133 ILRGLKYIHSADIIHRDLKPSNLAVNEDC 161
>MK14_MOUSE (P47811) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (CRK1) Length = 359 Score = 129 bits (325), Expect = 6e-30 Identities = 64/149 (42%), Positives = 93/149 (62%), Gaps = 1/149 (0%) Frame = +2 Query: 215 QTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXX 394 +T++E+ +Y + P+G GAYG VC++ + +T +VA+KK++ F + + A Sbjct: 14 KTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGHRVAVKKLSRPFQSIIHAKRTYRELRL 73 Query: 395 XXXXXXXNVIALKDIMMPIHR-RSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQ 571 NVI L D+ P F DVYLV+ LM DL+ IVK Q L++DH Q+ ++Q Sbjct: 74 LKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKC-QKLTDDHVQFLIYQ 132 Query: 572 LLRGLKYLHSAGILHRDLKPGNLLVNANC 658 +LRGLKY+HSA I+HRDLKP NL VN +C Sbjct: 133 ILRGLKYIHSADIIHRDLKPSNLAVNEDC 161
>MK14_PANTR (Q95NE7) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) Length = 359 Score = 128 bits (322), Expect = 1e-29 Identities = 64/149 (42%), Positives = 93/149 (62%), Gaps = 1/149 (0%) Frame = +2 Query: 215 QTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXX 394 +T++E+ +Y + P+G GAYG VC++ + +T +VA+KK++ F + + A Sbjct: 14 KTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRL 73 Query: 395 XXXXXXXNVIALKDIMMPIHR-RSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQ 571 NVI L D+ P F DVYLV+ LM DL+ IVK Q L++DH Q+ ++Q Sbjct: 74 LKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKC-QKLTDDHVQFLIYQ 132 Query: 572 LLRGLKYLHSAGILHRDLKPGNLLVNANC 658 +LRGLKY+HSA I+HRDLKP NL VN +C Sbjct: 133 ILRGLKYIHSADIIHRDLKPSNLAVNEDC 161
>MK14_HUMAN (Q16539) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAX-interacting prote Length = 359 Score = 128 bits (322), Expect = 1e-29 Identities = 64/149 (42%), Positives = 93/149 (62%), Gaps = 1/149 (0%) Frame = +2 Query: 215 QTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXX 394 +T++E+ +Y + P+G GAYG VC++ + +T +VA+KK++ F + + A Sbjct: 14 KTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRL 73 Query: 395 XXXXXXXNVIALKDIMMPIHR-RSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQ 571 NVI L D+ P F DVYLV+ LM DL+ IVK Q L++DH Q+ ++Q Sbjct: 74 LKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKC-QKLTDDHVQFLIYQ 132 Query: 572 LLRGLKYLHSAGILHRDLKPGNLLVNANC 658 +LRGLKY+HSA I+HRDLKP NL VN +C Sbjct: 133 ILRGLKYIHSADIIHRDLKPSNLAVNEDC 161
>MK14_CANFA (O02812) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) Length = 359 Score = 128 bits (322), Expect = 1e-29 Identities = 64/149 (42%), Positives = 93/149 (62%), Gaps = 1/149 (0%) Frame = +2 Query: 215 QTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXX 394 +T++E+ +Y + P+G GAYG VC++ + +T +VA+KK++ F + + A Sbjct: 14 KTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRL 73 Query: 395 XXXXXXXNVIALKDIMMPIHR-RSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQ 571 NVI L D+ P F DVYLV+ LM DL+ IVK Q L++DH Q+ ++Q Sbjct: 74 LKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKC-QKLTDDHVQFLIYQ 132 Query: 572 LLRGLKYLHSAGILHRDLKPGNLLVNANC 658 +LRGLKY+HSA I+HRDLKP NL VN +C Sbjct: 133 ILRGLKYIHSADIIHRDLKPSNLAVNEDC 161
>CPK1_CRYNE (Q8NK05) Mitogen-activated protein kinase CPK1 (EC 2.7.11.24)| (Stress-activated protein kinase CPK1) Length = 366 Score = 128 bits (321), Expect = 2e-29 Identities = 66/148 (44%), Positives = 94/148 (63%) Frame = +2 Query: 215 QTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXX 394 Q F + + Y + +G GAYG+V + + + +VAIK+I FD+ + Sbjct: 7 QINFNVPSTYKLEEIVGEGAYGLVVAGTHLPSGTQVAIKRITP-FDHTMFCQRTLREIKL 65 Query: 395 XXXXXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQL 574 N+I++ D++ P F +VYLV ELM+TDLH++++S Q LS+DHCQYF++Q Sbjct: 66 LRHFHHENIISILDLIQPESYEVFNEVYLVQELMETDLHRVIRS-QELSDDHCQYFVYQT 124 Query: 575 LRGLKYLHSAGILHRDLKPGNLLVNANC 658 LRGLK LHSA +LHRDLKP NLL+NANC Sbjct: 125 LRGLKALHSADVLHRDLKPSNLLLNANC 152
>MK03_HUMAN (P27361) Mitogen-activated protein kinase 3 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase 1) (MAPK 1) (p44-ERK1) (ERT2) (p44-MAPK) (Microtubule-associated protein 2 kinase) Length = 379 Score = 127 bits (320), Expect = 2e-29 Identities = 64/145 (44%), Positives = 94/145 (64%) Frame = +2 Query: 224 FEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXX 403 F++ +Y ++ IG GAYG+V S+ + +VAIKKI+ F+++ Sbjct: 36 FDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISP-FEHQTYCQRTLREIQILLR 94 Query: 404 XXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLRG 583 NVI ++DI+ + +DVY+V +LM+TDL++++KS Q LSNDH YFL+Q+LRG Sbjct: 95 FRHENVIGIRDILRASTLEAMRDVYIVQDLMETDLYKLLKSQQ-LSNDHICYFLYQILRG 153 Query: 584 LKYLHSAGILHRDLKPGNLLVNANC 658 LKY+HSA +LHRDLKP NLL+N C Sbjct: 154 LKYIHSANVLHRDLKPSNLLINTTC 178
>MK03_RAT (P21708) Mitogen-activated protein kinase 3 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase 1) (MAPK 1) (p44-ERK1) (ERT2) (p44-MAPK) (Microtubule-associated protein 2 kinase) (MNK1) Length = 380 Score = 127 bits (319), Expect = 3e-29 Identities = 64/145 (44%), Positives = 94/145 (64%) Frame = +2 Query: 224 FEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXX 403 F++ +Y ++ IG GAYG+V S+ + +VAIKKI+ F+++ Sbjct: 37 FDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISP-FEHQTYCQRTLREIQILLG 95 Query: 404 XXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLRG 583 NVI ++DI+ + +DVY+V +LM+TDL++++KS Q LSNDH YFL+Q+LRG Sbjct: 96 FRHENVIGIRDILRAPTLEAMRDVYIVQDLMETDLYKLLKSQQ-LSNDHICYFLYQILRG 154 Query: 584 LKYLHSAGILHRDLKPGNLLVNANC 658 LKY+HSA +LHRDLKP NLL+N C Sbjct: 155 LKYIHSANVLHRDLKPSNLLINTTC 179
>MK03_MOUSE (Q63844) Mitogen-activated protein kinase 3 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase 1) (MAPK 1) (p44-ERK1) (ERT2) (p44-MAPK) (Microtubule-associated protein 2 kinase) (MNK1) Length = 380 Score = 127 bits (319), Expect = 3e-29 Identities = 64/145 (44%), Positives = 94/145 (64%) Frame = +2 Query: 224 FEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXX 403 F++ +Y ++ IG GAYG+V S+ + +VAIKKI+ F+++ Sbjct: 37 FDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISP-FEHQTYCQRTLREIQILLR 95 Query: 404 XXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLRG 583 NVI ++DI+ + +DVY+V +LM+TDL++++KS Q LSNDH YFL+Q+LRG Sbjct: 96 FRHENVIGIRDILRAPTLEAMRDVYIVQDLMETDLYKLLKSQQ-LSNDHICYFLYQILRG 154 Query: 584 LKYLHSAGILHRDLKPGNLLVNANC 658 LKY+HSA +LHRDLKP NLL+N C Sbjct: 155 LKYIHSANVLHRDLKPSNLLINTTC 179
>MK01_HUMAN (P28482) Mitogen-activated protein kinase 1 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 2) (ERK-2) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) (p42-MAPK) (ERT1) Length = 359 Score = 127 bits (318), Expect = 4e-29 Identities = 64/146 (43%), Positives = 93/146 (63%) Frame = +2 Query: 221 MFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXX 400 +F++ +Y + IG GAYG+VCS+ + +VAIKKI+ F+++ Sbjct: 17 VFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISP-FEHQTYCQRTLREIKILL 75 Query: 401 XXXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLR 580 N+I + DI+ KDVY+V +LM+TDL++++K+ Q LSNDH YFL+Q+LR Sbjct: 76 RFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKT-QHLSNDHICYFLYQILR 134 Query: 581 GLKYLHSAGILHRDLKPGNLLVNANC 658 GLKY+HSA +LHRDLKP NLL+N C Sbjct: 135 GLKYIHSANVLHRDLKPSNLLLNTTC 160
>MK01_BOVIN (P46196) Mitogen-activated protein kinase 1 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 2) (ERK-2) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) (p42-MAPK) (ERT1) Length = 359 Score = 127 bits (318), Expect = 4e-29 Identities = 64/146 (43%), Positives = 93/146 (63%) Frame = +2 Query: 221 MFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXX 400 +F++ +Y + IG GAYG+VCS+ + +VAIKKI+ F+++ Sbjct: 17 VFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISP-FEHQTYCQRTLREIKILL 75 Query: 401 XXXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLR 580 N+I + DI+ KDVY+V +LM+TDL++++K+ Q LSNDH YFL+Q+LR Sbjct: 76 RFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKT-QHLSNDHICYFLYQILR 134 Query: 581 GLKYLHSAGILHRDLKPGNLLVNANC 658 GLKY+HSA +LHRDLKP NLL+N C Sbjct: 135 GLKYIHSANVLHRDLKPSNLLLNTTC 160
>MK14B_DROME (O61443) Mitogen-activated protein kinase 14B (EC 2.7.11.24) (MAP| kinase p38b) (D-p38b) Length = 365 Score = 127 bits (318), Expect = 4e-29 Identities = 65/152 (42%), Positives = 95/152 (62%), Gaps = 4/152 (2%) Frame = +2 Query: 215 QTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXX 394 +T +EI Y ++P+G+GAYG VC ++ + T+ KVAIKK+ F + V A Sbjct: 15 RTEWEIPETYQNLQPVGQGAYGQVCKAVVRGTSTKVAIKKLARPFQSAVHAKRTYRELRL 74 Query: 395 XXXXXXXNVIALKDIMMPIHRRS----FKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYF 562 NVI L D+ P F+ VY+V+ LMD DL+ I+++ Q LS+DH Q+ Sbjct: 75 LKHMDHENVIGLLDVFHPGQPADSLDQFQQVYMVTHLMDADLNNIIRT-QKLSDDHVQFL 133 Query: 563 LFQLLRGLKYLHSAGILHRDLKPGNLLVNANC 658 ++Q+LRGLKY+HSAG++HRDLKP N+ VN +C Sbjct: 134 VYQILRGLKYIHSAGVIHRDLKPSNIAVNEDC 165
>SUR1_CAEEL (P39745) Mitogen-activated protein kinase mpk-1 (EC 2.7.11.24) (MAP| kinase sur-1) Length = 444 Score = 126 bits (317), Expect = 5e-29 Identities = 65/146 (44%), Positives = 97/146 (66%) Frame = +2 Query: 221 MFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXX 400 +FE+ +YV + IG GAYG+V S+++ T ++VAIKKI+ F+++ Sbjct: 89 LFEVAPRYVNLSYIGEGAYGMVASALDTITRDRVAIKKISP-FEHQTFCQRTLREIKILN 147 Query: 401 XXXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLR 580 N+I +++I+ S KD+Y+V LM+TDL++++K+ Q LSNDH YFL+Q+LR Sbjct: 148 RFKHENIINIQEIIRSETVDSLKDIYIVQCLMETDLYKLLKT-QKLSNDHVCYFLYQILR 206 Query: 581 GLKYLHSAGILHRDLKPGNLLVNANC 658 GLKY+HSA +LHRDLKP NLL+N C Sbjct: 207 GLKYIHSANVLHRDLKPSNLLLNTTC 232
>MK11_MOUSE (Q9WUI1) Mitogen-activated protein kinase 11 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38B) Length = 364 Score = 126 bits (317), Expect = 5e-29 Identities = 64/149 (42%), Positives = 93/149 (62%), Gaps = 1/149 (0%) Frame = +2 Query: 215 QTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXX 394 +T++E+ + ++P+G GAYG VCS+ + +KVA+KK++ F + + A Sbjct: 15 KTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRL 74 Query: 395 XXXXXXXNVIALKDIMMPIHR-RSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQ 571 NVI L D+ P F +VYLV+ LM DL+ IVK Q LS++H Q+ ++Q Sbjct: 75 LKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKC-QALSDEHVQFLVYQ 133 Query: 572 LLRGLKYLHSAGILHRDLKPGNLLVNANC 658 LLRGLKY+HSAGI+HRDLKP N+ VN +C Sbjct: 134 LLRGLKYIHSAGIIHRDLKPSNVAVNEDC 162
>MK14B_CYPCA (Q9I958) Mitogen-activated protein kinase 14b (EC 2.7.11.24)| (Mitogen-activated protein kinase p38b) (MAP kinase p38b) (cp38b) Length = 361 Score = 126 bits (317), Expect = 5e-29 Identities = 64/149 (42%), Positives = 93/149 (62%), Gaps = 1/149 (0%) Frame = +2 Query: 215 QTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXX 394 +T++E+ +Y + P+G GAYG VCS+++ ++ +VA+KK++ F + + A Sbjct: 16 KTIWEVPERYQNLSPVGSGAYGSVCSALDTKSGLRVAVKKLSRPFQSMIHAKRTYRELRL 75 Query: 395 XXXXXXXNVIALKDIMMPIH-RRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQ 571 NVI L D P F DVYLV+ LM DL+ IVK Q L++DH Q+ ++Q Sbjct: 76 LKHMKHENVIGLLDAFSPATCLAGFNDVYLVTHLMGADLNNIVKC-QKLTDDHVQFLIYQ 134 Query: 572 LLRGLKYLHSAGILHRDLKPGNLLVNANC 658 +LRGLKY+HSA I+HRDLKP NL VN +C Sbjct: 135 ILRGLKYIHSADIIHRDLKPSNLAVNEDC 163
>MK01_RAT (P63086) Mitogen-activated protein kinase 1 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 2) (ERK-2) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) (p42-MAPK) (ERT1) Length = 357 Score = 126 bits (317), Expect = 5e-29 Identities = 64/146 (43%), Positives = 93/146 (63%) Frame = +2 Query: 221 MFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXX 400 +F++ +Y + IG GAYG+VCS+ + +VAIKKI+ F+++ Sbjct: 15 VFDVGPRYTNLSYIGEGAYGMVCSAYDNLNKVRVAIKKISP-FEHQTYCQRTLREIKILL 73 Query: 401 XXXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLR 580 N+I + DI+ KDVY+V +LM+TDL++++K+ Q LSNDH YFL+Q+LR Sbjct: 74 RFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKT-QHLSNDHICYFLYQILR 132 Query: 581 GLKYLHSAGILHRDLKPGNLLVNANC 658 GLKY+HSA +LHRDLKP NLL+N C Sbjct: 133 GLKYIHSANVLHRDLKPSNLLLNTTC 158
>MK01_MOUSE (P63085) Mitogen-activated protein kinase 1 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 2) (ERK-2) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) (p42-MAPK) (ERT1) Length = 357 Score = 126 bits (317), Expect = 5e-29 Identities = 64/146 (43%), Positives = 93/146 (63%) Frame = +2 Query: 221 MFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXX 400 +F++ +Y + IG GAYG+VCS+ + +VAIKKI+ F+++ Sbjct: 15 VFDVGPRYTNLSYIGEGAYGMVCSAYDNLNKVRVAIKKISP-FEHQTYCQRTLREIKILL 73 Query: 401 XXXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLR 580 N+I + DI+ KDVY+V +LM+TDL++++K+ Q LSNDH YFL+Q+LR Sbjct: 74 RFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKT-QHLSNDHICYFLYQILR 132 Query: 581 GLKYLHSAGILHRDLKPGNLLVNANC 658 GLKY+HSA +LHRDLKP NLL+N C Sbjct: 133 GLKYIHSANVLHRDLKPSNLLLNTTC 158
>MK13_MOUSE (Q9Z1B7) Mitogen-activated protein kinase 13 (EC 2.7.11.24)| (Stress-activated protein kinase 4) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) Length = 366 Score = 126 bits (316), Expect = 7e-29 Identities = 67/149 (44%), Positives = 89/149 (59%), Gaps = 1/149 (0%) Frame = +2 Query: 215 QTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXX 394 +T +E+ Y+ +G GAYG VCS+I++ T EKVAIKK++ F + + A Sbjct: 16 KTAWELPKTYLAPAHVGSGAYGAVCSAIDKRTGEKVAIKKLSRPFQSEIFAKRAYRELLL 75 Query: 395 XXXXXXXNVIALKDIMMPIHR-RSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQ 571 NVI L D+ P RSF D YLV M TDL +I+ S D QY ++Q Sbjct: 76 LKHMHHENVIGLLDVFTPASSLRSFHDFYLVMPFMQTDLQKIM--GMEFSEDKVQYLVYQ 133 Query: 572 LLRGLKYLHSAGILHRDLKPGNLLVNANC 658 +L+GLKY+HSAGI+HRDLKPGNL VN +C Sbjct: 134 MLKGLKYIHSAGIVHRDLKPGNLAVNEDC 162
>ERKA_DROME (P40417) Mitogen-activated protein kinase ERK-A (EC 2.7.11.24)| (Extracellular-regulated kinase A) (Protein rolled) Length = 376 Score = 126 bits (316), Expect = 7e-29 Identities = 65/146 (44%), Positives = 96/146 (65%) Frame = +2 Query: 221 MFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXX 400 +FE+ +Y+ + IG GAYG+V S+ + TN++VAIKKI+ F+++ Sbjct: 31 IFEVGPRYIKLAYIGEGAYGMVVSADDTLTNQRVAIKKISP-FEHQTYCQRTLREITILT 89 Query: 401 XXXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLR 580 N+I ++DI+ +DVY+V LM+TDL++++K+ Q LSNDH YFL+Q+LR Sbjct: 90 RFKHENIIDIRDILRVDSIDQMRDVYIVQCLMETDLYKLLKT-QRLSNDHICYFLYQILR 148 Query: 581 GLKYLHSAGILHRDLKPGNLLVNANC 658 GLKY+HSA +LHRDLKP NLL+N C Sbjct: 149 GLKYIHSANVLHRDLKPSNLLLNKTC 174
>SLT2_YEAST (Q00772) Mitogen-activated protein kinase SLT2/MPK1 (EC 2.7.11.24)| (MAP kinase MPK1) Length = 484 Score = 125 bits (313), Expect = 1e-28 Identities = 70/159 (44%), Positives = 95/159 (59%), Gaps = 4/159 (2%) Frame = +2 Query: 194 KHYYTMWQTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEK--VAIKKINNVFDNRVDA 367 +H + ++ F +D ++ IK IG GAYGIVCS+ E E VAIKK+ NVF + Sbjct: 7 RHTFKVFNQDFSVDKRFQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLC 66 Query: 368 XXXXXXXXXXXXXXXX-NVIALKDIMMPIHRR-SFKDVYLVSELMDTDLHQIVKSSQPLS 541 N+ L D+ + + S +YL ELM+ D+HQI+KS QPL+ Sbjct: 67 KRSLRELKLLRHFRGHKNITCLYDMDIVFYPDGSINGLYLYEELMECDMHQIIKSGQPLT 126 Query: 542 NDHCQYFLFQLLRGLKYLHSAGILHRDLKPGNLLVNANC 658 + H Q F +Q+L GLKY+HSA +LHRDLKPGNLLVNA+C Sbjct: 127 DAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADC 165
>MK01_XENLA (P26696) Mitogen-activated protein kinase 1 (EC 2.7.11.24) (Myelin| xP42 protein kinase) (Myelin basic protein kinase) (MBP kinase) (M phase MAP kinase) Length = 361 Score = 124 bits (310), Expect = 3e-28 Identities = 64/145 (44%), Positives = 91/145 (62%) Frame = +2 Query: 224 FEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXX 403 F++ +Y + IG GAYG+VCS+ +VAIKKI+ F+++ Sbjct: 22 FDVGPRYTNLSYIGEGAYGMVCSAHCNINKVRVAIKKISP-FEHQTYCQRTLREIKILLR 80 Query: 404 XXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLRG 583 N+I + DI+ KDVY+V +LM+TDL++++K+ Q LSNDH YFL+Q+LRG Sbjct: 81 FKHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKT-QHLSNDHICYFLYQILRG 139 Query: 584 LKYLHSAGILHRDLKPGNLLVNANC 658 LKY+HSA +LHRDLKP NLL+N C Sbjct: 140 LKYIHSANVLHRDLKPSNLLLNTTC 164
>MK13_RAT (Q9WTY9) Mitogen-activated protein kinase 13 (EC 2.7.11.24)| (Stress-activated protein kinase 4) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) Length = 366 Score = 123 bits (309), Expect = 4e-28 Identities = 65/149 (43%), Positives = 90/149 (60%), Gaps = 1/149 (0%) Frame = +2 Query: 215 QTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXX 394 +T +E+ Y+ +G GAYG VCS+I++ T EKVAIKK++ F + + A Sbjct: 16 KTAWELPKTYLAPAHVGSGAYGAVCSAIDKRTGEKVAIKKLSRPFQSEIFAKRAYRELLL 75 Query: 395 XXXXXXXNVIALKDIMMPIHR-RSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQ 571 NVI L D+ P R+F+D YLV M TDL +I+ S + QY ++Q Sbjct: 76 LKHMHHENVIGLLDVYTPATSVRNFQDFYLVMPFMQTDLQKIM--GMEFSEEKVQYLVYQ 133 Query: 572 LLRGLKYLHSAGILHRDLKPGNLLVNANC 658 +L+GLKY+HSAGI+HRDLKPGNL VN +C Sbjct: 134 MLKGLKYIHSAGIVHRDLKPGNLAVNEDC 162
>SPM1_SCHPO (Q92398) Mitogen-activated protein kinase spm1 (EC 2.7.11.24) (MAP| kinase spm1) (MAP kinase pmk1) Length = 422 Score = 122 bits (307), Expect = 7e-28 Identities = 64/155 (41%), Positives = 96/155 (61%), Gaps = 3/155 (1%) Frame = +2 Query: 203 YTMWQTMFEIDTKYVPIKPIGRGAYGIVCSSIN--QETNEKVAIKKINNVFDNRV-DAXX 373 Y ++ ++ + +K +G+GAYGIVC++ N + E VAIKKI NVF + Sbjct: 8 YRVFNQEMYVEPNFKVVKELGQGAYGIVCAARNVASKDQEAVAIKKITNVFSKSILTKRA 67 Query: 374 XXXXXXXXXXXXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHC 553 N+ + D+ + I+ +F +VY+ ELM+ DL+ I+KS QPL++ H Sbjct: 68 LREIKLLIHFRNHRNITCIYDLDI-INPYNFNEVYIYEELMEADLNAIIKSGQPLTDAHF 126 Query: 554 QYFLFQLLRGLKYLHSAGILHRDLKPGNLLVNANC 658 Q F++Q+L GLKY+HSA ++HRDLKPGNLLVNA+C Sbjct: 127 QSFIYQILCGLKYIHSANVIHRDLKPGNLLVNADC 161
>MK12_RAT (Q63538) Mitogen-activated protein kinase 12 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 6) (ERK-6) (Stress-activated protein kinase 3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) Length = 367 Score = 122 bits (306), Expect = 9e-28 Identities = 66/168 (39%), Positives = 95/168 (56%), Gaps = 1/168 (0%) Frame = +2 Query: 158 MVDPPNGIGNHGKHYYTMWQTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKI 337 M PP G + + +T +E+ Y ++P+G GAYG VCS+++ T KVAIKK+ Sbjct: 1 MSSPPPA--RKGFYRQEVTKTAWEVRAVYQDLQPVGSGAYGAVCSAVDSRTGNKVAIKKL 58 Query: 338 NNVFDNRVDAXXXXXXXXXXXXXXXXNVIALKDIMMPIHRRS-FKDVYLVSELMDTDLHQ 514 F + + A NVI L D+ P F D YLV M TDL + Sbjct: 59 YRPFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGK 118 Query: 515 IVKSSQPLSNDHCQYFLFQLLRGLKYLHSAGILHRDLKPGNLLVNANC 658 ++K + LS D Q+ ++Q+L+GLKY+H+AG++HRDLKPGNL VN +C Sbjct: 119 LMKH-ETLSEDRIQFLVYQMLKGLKYIHAAGVIHRDLKPGNLAVNEDC 165
>MK12_MOUSE (O08911) Mitogen-activated protein kinase 12 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 6) (ERK-6) (Stress-activated protein kinase 3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) Length = 367 Score = 122 bits (306), Expect = 9e-28 Identities = 66/168 (39%), Positives = 95/168 (56%), Gaps = 1/168 (0%) Frame = +2 Query: 158 MVDPPNGIGNHGKHYYTMWQTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKI 337 M PP G + + +T +E+ Y ++P+G GAYG VCS+++ T KVAIKK+ Sbjct: 1 MSSPPPA--RKGFYRQEVTKTAWEVRAVYQDLQPVGSGAYGAVCSAVDSRTGNKVAIKKL 58 Query: 338 NNVFDNRVDAXXXXXXXXXXXXXXXXNVIALKDIMMPIHRRS-FKDVYLVSELMDTDLHQ 514 F + + A NVI L D+ P F D YLV M TDL + Sbjct: 59 YRPFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDESLDDFTDFYLVMPFMGTDLGK 118 Query: 515 IVKSSQPLSNDHCQYFLFQLLRGLKYLHSAGILHRDLKPGNLLVNANC 658 ++K + LS D Q+ ++Q+L+GLKY+H+AG++HRDLKPGNL VN +C Sbjct: 119 LMKH-ETLSEDRIQFLVYQMLKGLKYIHAAGVIHRDLKPGNLAVNEDC 165
>MK13_HUMAN (O15264) Mitogen-activated protein kinase 13 (EC 2.7.11.24)| (Stress-activated protein kinase 4) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) Length = 365 Score = 122 bits (305), Expect = 1e-27 Identities = 64/149 (42%), Positives = 89/149 (59%), Gaps = 1/149 (0%) Frame = +2 Query: 215 QTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXX 394 +T +E+ YV +G GAYG VCS+I++ + EKVAIKK++ F + + A Sbjct: 16 KTAWELPKTYVSPTHVGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLL 75 Query: 395 XXXXXXXNVIALKDIMMPIHR-RSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQ 571 NVI L D+ P R+F D YLV M TDL +I+ S + QY ++Q Sbjct: 76 LKHMQHENVIGLLDVFTPASSLRNFYDFYLVMPFMQTDLQKIM--GMEFSEEKIQYLVYQ 133 Query: 572 LLRGLKYLHSAGILHRDLKPGNLLVNANC 658 +L+GLKY+HSAG++HRDLKPGNL VN +C Sbjct: 134 MLKGLKYIHSAGVVHRDLKPGNLAVNEDC 162
>MK14A_DROME (O62618) Mitogen-activated protein kinase 14A (EC 2.7.11.24) (MAP| kinase p38a) (p38 MAPK) (Dp38) (D-p38a) Length = 366 Score = 122 bits (305), Expect = 1e-27 Identities = 66/152 (43%), Positives = 92/152 (60%), Gaps = 4/152 (2%) Frame = +2 Query: 215 QTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXX 394 +T +EI Y ++P+G GAYG V ++ + TN VAIKK+ F + V A Sbjct: 16 RTEWEIPDIYQDLQPVGSGAYGQVSKAVVRGTNMHVAIKKLARPFQSAVHAKRTYRELRL 75 Query: 395 XXXXXXXNVIALKDIMMPIHRR----SFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYF 562 NVI L DI P +F+ VYLV+ LMD DL+ I++ Q LS+DH Q+ Sbjct: 76 LKHMDHENVIGLLDIFHPHPANGSLENFQQVYLVTHLMDADLNNIIRM-QHLSDDHVQFL 134 Query: 563 LFQLLRGLKYLHSAGILHRDLKPGNLLVNANC 658 ++Q+LRGLKY+HSAG++HRDLKP N+ VN +C Sbjct: 135 VYQILRGLKYIHSAGVIHRDLKPSNIAVNEDC 166
>FUS3_YEAST (P16892) Mitogen-activated protein kinase FUS3 (EC 2.7.11.24) (MAP| kinase FUS3) Length = 353 Score = 121 bits (304), Expect = 2e-27 Identities = 60/133 (45%), Positives = 86/133 (64%) Frame = +2 Query: 260 IGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNVIALKDI 439 +G GAYG+VCS+ ++ T E VAIKKI FD + A N+I + +I Sbjct: 19 LGEGAYGVVCSATHKPTGEIVAIKKIEP-FDKPLFALRTLREIKILKHFKHENIITIFNI 77 Query: 440 MMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLRGLKYLHSAGILHR 619 P +F +VY++ ELM TDLH+++ S+Q LS+DH QYF++Q LR +K LH + ++HR Sbjct: 78 QRPDSFENFNEVYIIQELMQTDLHRVI-STQMLSDDHIQYFIYQTLRAVKVLHGSNVIHR 136 Query: 620 DLKPGNLLVNANC 658 DLKP NLL+N+NC Sbjct: 137 DLKPSNLLINSNC 149
>MK14B_BRARE (Q9DGE1) Mitogen-activated protein kinase 14b (EC 2.7.11.24)| (Mitogen-activated protein kinase p38b) (MAP kinase p38b) (zp38b) Length = 348 Score = 120 bits (301), Expect = 4e-27 Identities = 62/149 (41%), Positives = 90/149 (60%), Gaps = 1/149 (0%) Frame = +2 Query: 215 QTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXX 394 +T++E+ +Y + P+G GAYG V S+ + + +VA+KK++ F + + A Sbjct: 16 KTIWEVPERYQNLSPVGSGAYGSVMSAFDGKAGLRVAVKKLSRPFQSIIHAKRTYRELRL 75 Query: 395 XXXXXXXNVIALKDIMMPIHR-RSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQ 571 NVI L D+ P F DVYLV+ LM DL+ IVK Q L++DH Q+ ++Q Sbjct: 76 LKHMKHENVIGLLDVFSPATSLEGFNDVYLVTHLMGADLNNIVKC-QKLTDDHVQFLIYQ 134 Query: 572 LLRGLKYLHSAGILHRDLKPGNLLVNANC 658 +LR LKY+HSA I+HRDLKP NL VN +C Sbjct: 135 ILRALKYIHSADIIHRDLKPSNLAVNEDC 163
>MK13_PANTR (Q9N272) Mitogen-activated protein kinase 13 (EC 2.7.11.24)| (Stress-activated protein kinase 4) Length = 365 Score = 120 bits (300), Expect = 5e-27 Identities = 63/145 (43%), Positives = 86/145 (59%), Gaps = 1/145 (0%) Frame = +2 Query: 227 EIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXX 406 E+ YV +G GAYG VCS+I++ + EKVAIKK++ F + + A Sbjct: 20 ELXKTYVSPTHVGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHM 79 Query: 407 XXXNVIALKDIMMPIHR-RSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLRG 583 NVI L D+ P R+F D YLV M TDL +I+ S + QY ++Q+L+G Sbjct: 80 QHENVIGLLDVFTPASSLRNFHDFYLVMXFMQTDLQKIM--XMEFSEEKIQYLVYQMLKG 137 Query: 584 LKYLHSAGILHRDLKPGNLLVNANC 658 LKY+HSAG++HRDLKPGNL VN +C Sbjct: 138 LKYIHSAGVVHRDLKPGNLAVNEDC 162
>JNK_DROME (P92208) Stress-activated protein kinase JNK (EC 2.7.11.24) (dJNK)| (Protein basket) Length = 372 Score = 119 bits (299), Expect = 6e-27 Identities = 63/158 (39%), Positives = 92/158 (58%), Gaps = 1/158 (0%) Frame = +2 Query: 188 HGKHYYTMWQTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDA 367 H + + T F I ++Y+ ++PIG GA GIVC++ + T + VAIKK++ F N A Sbjct: 6 HQHYTVEVGDTNFTIHSRYINLRPIGSGAQGIVCAAYDTITQQNVAIKKLSRPFQNVTHA 65 Query: 368 XXXXXXXXXXXXXXXXNVIALKDIMMPIHR-RSFKDVYLVSELMDTDLHQIVKSSQPLSN 544 N+I L + P F+DVYLV ELMD +L Q+++ L + Sbjct: 66 KRAYREFKLMKLVNHKNIIGLLNAFTPQRNLEEFQDVYLVMELMDANLCQVIQMD--LDH 123 Query: 545 DHCQYFLFQLLRGLKYLHSAGILHRDLKPGNLLVNANC 658 D Y L+Q+L G+K+LHSAGI+HRDLKP N++V A+C Sbjct: 124 DRMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKADC 161
>MK11_HUMAN (Q15759) Mitogen-activated protein kinase 11 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38b) (p38-2) (Stress-activated protein kinase 2) Length = 372 Score = 118 bits (296), Expect = 1e-26 Identities = 61/156 (39%), Positives = 92/156 (58%), Gaps = 8/156 (5%) Frame = +2 Query: 215 QTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXX 394 +T++E+ + ++P+G GAYG VCS+ + +KVA+KK++ F + + A Sbjct: 15 KTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRL 74 Query: 395 XXXXXXXNVIALKDIMMPIHR-RSFKDVYLVSELMDTDLHQIVK-------SSQPLSNDH 550 NVI L D+ P F +VYLV+ LM DL+ IVK ++ ++H Sbjct: 75 LKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQAGAHQGARLALDEH 134 Query: 551 CQYFLFQLLRGLKYLHSAGILHRDLKPGNLLVNANC 658 Q+ ++QLLRGLKY+HSAGI+HRDLKP N+ VN +C Sbjct: 135 VQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDC 170
>MK12_HUMAN (P53778) Mitogen-activated protein kinase 12 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 6) (ERK-6) (ERK5) (Stress-activated protein kinase 3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) Length = 367 Score = 118 bits (296), Expect = 1e-26 Identities = 65/168 (38%), Positives = 94/168 (55%), Gaps = 1/168 (0%) Frame = +2 Query: 158 MVDPPNGIGNHGKHYYTMWQTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKI 337 M PP G + + +T +E+ Y ++P+G GAYG VCS+++ T KVAIKK+ Sbjct: 1 MSSPPPA--RSGFYRQEVTKTAWEVRAVYRDLQPVGSGAYGAVCSAVDGRTGAKVAIKKL 58 Query: 338 NNVFDNRVDAXXXXXXXXXXXXXXXXNVIALKDIMMPIHRRS-FKDVYLVSELMDTDLHQ 514 F + + A NVI L D+ P F D YLV M TDL + Sbjct: 59 YRPFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGK 118 Query: 515 IVKSSQPLSNDHCQYFLFQLLRGLKYLHSAGILHRDLKPGNLLVNANC 658 ++K + L D Q+ ++Q+L+GL+Y+H+AGI+HRDLKPGNL VN +C Sbjct: 119 LMKHEK-LGEDRIQFLVYQMLKGLRYIHAAGIIHRDLKPGNLAVNEDC 165
>MKC1_CANAL (P43068) Mitogen-activated protein kinase MKC1 (EC 2.7.11.24) (MAP| kinase MKC1) Length = 501 Score = 118 bits (295), Expect = 2e-26 Identities = 67/177 (37%), Positives = 100/177 (56%), Gaps = 20/177 (11%) Frame = +2 Query: 188 HGKHYYTMWQTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKV--------------- 322 +G+ ++ F ID+++ +K +G GAYGIVCS+ ++KV Sbjct: 10 YGRSVNKVYNQEFIIDSRFKIVKELGHGAYGIVCSAKYDNGSKKVPDSNNGNASSSANAS 69 Query: 323 --AIKKINNVFD-NRVDAXXXXXXXXXXXXXXXXNVIALKDIMMPIHRRS--FKDVYLVS 487 AIKKI N+F N + N+ L D+ + + + F ++YL Sbjct: 70 FVAIKKITNIFSKNILCKRALRELKLLQFFRGHKNITCLYDLDIIPNPMTGEFNEIYLYE 129 Query: 488 ELMDTDLHQIVKSSQPLSNDHCQYFLFQLLRGLKYLHSAGILHRDLKPGNLLVNANC 658 ELM+ D+HQI++S QPLS+ H Q F++Q+L GL ++HSA +LHRDLKPGNLLVNA+C Sbjct: 130 ELMECDMHQIIRSGQPLSDQHYQSFIYQVLCGLNFIHSADVLHRDLKPGNLLVNADC 186
>MK12_BRARE (O42376) Mitogen-activated protein kinase 12 (EC 2.7.11.24)| (Stress-activated protein kinase 3) Length = 363 Score = 117 bits (294), Expect = 2e-26 Identities = 60/149 (40%), Positives = 90/149 (60%), Gaps = 1/149 (0%) Frame = +2 Query: 215 QTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXX 394 +T++E+ +Y +K +G GAYG VC ++++ T KVAIKK++ F + + A Sbjct: 16 KTIWEVPDRYKDLKQVGTGAYGTVCYALDRRTGAKVAIKKLHRPFQSDLFAKRAYRELRL 75 Query: 395 XXXXXXXNVIALKDIMMP-IHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQ 571 NVI L D+ + F D YLV M TDL +++K + LS + QY ++Q Sbjct: 76 LKHMKHDNVIGLVDVFTADLSLDRFHDFYLVMPFMGTDLGKLMKMER-LSEERVQYLVYQ 134 Query: 572 LLRGLKYLHSAGILHRDLKPGNLLVNANC 658 +L+GLKY+H+AGI+HRDLKPGNL +N C Sbjct: 135 MLKGLKYIHAAGIIHRDLKPGNLAINEEC 163
>KSS1_YEAST (P14681) Mitogen-activated protein kinase KSS1 (EC 2.7.11.24) (MAP| kinase KSS1) (Kinase suppressor of SST2) Length = 368 Score = 115 bits (288), Expect = 1e-25 Identities = 60/149 (40%), Positives = 87/149 (58%), Gaps = 4/149 (2%) Frame = +2 Query: 224 FEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXX 403 F+I ++Y + IG GAYG VCS+I++ + KVAIKKI Sbjct: 7 FDIPSQYKLVDLIGEGAYGTVCSAIHKPSGIKVAIKKIQPFSKKLFVTRTIREIKLLRYF 66 Query: 404 XXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQP----LSNDHCQYFLFQ 571 N+I++ D + P+ VYLV ELM+TDL +++ + LS+DH QYF +Q Sbjct: 67 HEHENIISILDKVRPVSIDKLNAVYLVEELMETDLQKVINNQNSGFSTLSDDHVQYFTYQ 126 Query: 572 LLRGLKYLHSAGILHRDLKPGNLLVNANC 658 +LR LK +HSA ++HRD+KP NLL+N+NC Sbjct: 127 ILRALKSIHSAQVIHRDIKPSNLLLNSNC 155
>JNK_SUBDO (Q966Y3) Stress-activated protein kinase JNK (EC 2.7.11.24)| Length = 361 Score = 115 bits (287), Expect = 2e-25 Identities = 62/156 (39%), Positives = 90/156 (57%), Gaps = 3/156 (1%) Frame = +2 Query: 200 YYT--MWQTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXX 373 YY+ + T+F + +Y + IG GA G+VCS+ + T EK+AIKK+ F N A Sbjct: 6 YYSQRVGDTVFTVQKRYTNLTNIGSGAQGVVCSAFDTVTQEKIAIKKLVKPFQNETYAKR 65 Query: 374 XXXXXXXXXXXXXXNVIALKDIMMPIHRRS-FKDVYLVSELMDTDLHQIVKSSQPLSNDH 550 N+I LK++ P F+DVY+V ELMD +L +++ L +D Sbjct: 66 AFRELRLMKMVDHKNIIGLKNLFTPAKSLDDFQDVYIVMELMDANLCRVIGIE--LDHDR 123 Query: 551 CQYFLFQLLRGLKYLHSAGILHRDLKPGNLLVNANC 658 Y L+QLL G+K+LHSAGI+HRDLKP N++V +C Sbjct: 124 MSYLLYQLLCGIKHLHSAGIIHRDLKPSNIVVKEDC 159
>PMK2_CAEEL (Q8MXI4) Mitogen-activated protein kinase pmk-2 (EC 2.7.11.24) (p38| MAP kinase 2) (Stress-activated protein kinase pmk-2) Length = 419 Score = 114 bits (286), Expect = 2e-25 Identities = 63/164 (38%), Positives = 92/164 (56%), Gaps = 1/164 (0%) Frame = +2 Query: 170 PNGIGNHGKHYYTMWQTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVF 349 P I G H + +T + + Y +KP+G GAYG+VC++ + T ++VAIKK F Sbjct: 25 PPEITPEGYHEVELNKTKWVLPQWYNSLKPLGEGAYGVVCTAEYEPTGDRVAIKKFFRPF 84 Query: 350 DNRVDAXXXXXXXXXXXXXXXXNVIALKDIMMPI-HRRSFKDVYLVSELMDTDLHQIVKS 526 + + A NV+ + D+ P S +VY VS LM +DL I+K Sbjct: 85 QSTIHAKRTYRELKLLRTLQHDNVLEMIDVFTPDPDASSLNNVYFVSVLMGSDLQNIMKI 144 Query: 527 SQPLSNDHCQYFLFQLLRGLKYLHSAGILHRDLKPGNLLVNANC 658 Q L+++ Q ++Q+LRGLKY+HSAGI+HRDLKP N+ VN C Sbjct: 145 -QRLTDEQIQLLIYQVLRGLKYIHSAGIIHRDLKPSNIAVNERC 187
>PMK1_CAEEL (Q17446) Mitogen-activated protein kinase pmk-1 (EC 2.7.11.24) (p38| MAP kinase 1) (Stress-activated protein kinase pmk-1) Length = 377 Score = 114 bits (285), Expect = 3e-25 Identities = 61/157 (38%), Positives = 90/157 (57%), Gaps = 1/157 (0%) Frame = +2 Query: 191 GKHYYTMWQTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAX 370 G + + ++++ + Y+ + PIG GAYG VC++ + +VAIKK N F + + A Sbjct: 18 GYYVVELNRSVWVVPNYYINLTPIGTGAYGTVCAAECTRSGTRVAIKKFNRPFQSIIHAR 77 Query: 371 XXXXXXXXXXXXXXXNVIALKDIMMPIHR-RSFKDVYLVSELMDTDLHQIVKSSQPLSND 547 N+I L D+ P +DVY VS LM DL I+K Q L++D Sbjct: 78 RTYRELRLLRCMCHENIIDLLDVFTPNENVNDIEDVYFVSMLMGADLSNILKI-QRLNDD 136 Query: 548 HCQYFLFQLLRGLKYLHSAGILHRDLKPGNLLVNANC 658 H Q+ ++Q+LRGLKY+HSA I+HRDLKP N+ VN +C Sbjct: 137 HIQFLVYQILRGLKYIHSADIIHRDLKPSNIAVNEDC 173
>MK08_BRARE (Q9DGD9) Mitogen-activated protein kinase 8 (EC 2.7.11.24)| (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1) Length = 384 Score = 113 bits (282), Expect = 6e-25 Identities = 60/158 (37%), Positives = 93/158 (58%), Gaps = 3/158 (1%) Frame = +2 Query: 194 KHYYTM--WQTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDA 367 K YY++ + F + +Y ++PIG GA GIVCS+ + + VAIKK++ F N+ A Sbjct: 8 KEYYSIDVGDSTFTVLKRYQNLRPIGSGAQGIVCSAYDHVLDRNVAIKKLSRPFQNQTHA 67 Query: 368 XXXXXXXXXXXXXXXXNVIALKDIMMPIHR-RSFKDVYLVSELMDTDLHQIVKSSQPLSN 544 N+I L ++ P F+DVYLV ELMD +L Q+++ L + Sbjct: 68 KRAYRELVLMKCVNHKNIIGLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQME--LDH 125 Query: 545 DHCQYFLFQLLRGLKYLHSAGILHRDLKPGNLLVNANC 658 + Y L+Q+L G+K+LH+AGI+HRDLKP N++V ++C Sbjct: 126 ERLSYLLYQMLCGIKHLHAAGIIHRDLKPSNIVVKSDC 163
>MK10_MOUSE (Q61831) Mitogen-activated protein kinase 10 (EC 2.7.11.24)| (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3) (MAP kinase p49 3F12) Length = 464 Score = 112 bits (279), Expect = 1e-24 Identities = 58/146 (39%), Positives = 88/146 (60%), Gaps = 1/146 (0%) Frame = +2 Query: 224 FEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXX 403 F + +Y +KPIG GA GIVC++ + + VAIKK++ F N+ A Sbjct: 58 FTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKC 117 Query: 404 XXXXNVIALKDIMMPIHR-RSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLR 580 N+I+L ++ P F+DVYLV ELMD +L Q+++ L ++ Y L+Q+L Sbjct: 118 VNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQME--LDHERMSYLLYQMLC 175 Query: 581 GLKYLHSAGILHRDLKPGNLLVNANC 658 G+K+LHSAGI+HRDLKP N++V ++C Sbjct: 176 GIKHLHSAGIIHRDLKPSNIVVKSDC 201
>MK10_HUMAN (P53779) Mitogen-activated protein kinase 10 (EC 2.7.11.24)| (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3) (MAP kinase p49 3F12) Length = 464 Score = 112 bits (279), Expect = 1e-24 Identities = 58/146 (39%), Positives = 88/146 (60%), Gaps = 1/146 (0%) Frame = +2 Query: 224 FEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXX 403 F + +Y +KPIG GA GIVC++ + + VAIKK++ F N+ A Sbjct: 58 FTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKC 117 Query: 404 XXXXNVIALKDIMMPIHR-RSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLR 580 N+I+L ++ P F+DVYLV ELMD +L Q+++ L ++ Y L+Q+L Sbjct: 118 VNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQME--LDHERMSYLLYQMLC 175 Query: 581 GLKYLHSAGILHRDLKPGNLLVNANC 658 G+K+LHSAGI+HRDLKP N++V ++C Sbjct: 176 GIKHLHSAGIIHRDLKPSNIVVKSDC 201
>MK08B_CYPCA (O42099) Mitogen-activated protein kinase 8B (EC 2.7.11.24)| (Stress-activated protein kinase JNKb) (c-Jun N-terminal kinase B) Length = 427 Score = 112 bits (279), Expect = 1e-24 Identities = 60/158 (37%), Positives = 91/158 (57%), Gaps = 3/158 (1%) Frame = +2 Query: 194 KHYYTM--WQTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDA 367 K +Y++ + F + +Y ++PIG GA GIVCS+ + VAIKK++ F N+ A Sbjct: 8 KEFYSVDVGDSTFTVLKRYQNLRPIGSGAQGIVCSAYDHNLERNVAIKKLSRPFQNQTHA 67 Query: 368 XXXXXXXXXXXXXXXXNVIALKDIMMPIHR-RSFKDVYLVSELMDTDLHQIVKSSQPLSN 544 N+I L ++ P F+DVYLV ELMD +L Q+++ L + Sbjct: 68 KRAYRELVLMKCVNHKNIIGLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQME--LDH 125 Query: 545 DHCQYFLFQLLRGLKYLHSAGILHRDLKPGNLLVNANC 658 + Y L+Q+L G K+LHSAGI+HRDLKP N++V ++C Sbjct: 126 ERLSYLLYQMLCGTKHLHSAGIIHRDLKPSNIVVKSDC 163
>MK10_RAT (P49187) Mitogen-activated protein kinase 10 (EC 2.7.11.24)| (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3) (SAPK-beta) (p54-beta) Length = 464 Score = 110 bits (275), Expect = 4e-24 Identities = 57/146 (39%), Positives = 87/146 (59%), Gaps = 1/146 (0%) Frame = +2 Query: 224 FEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXX 403 F + +Y +KPIG GA GIVC++ + + VAIKK++ F N+ A Sbjct: 58 FTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKC 117 Query: 404 XXXXNVIALKDIMMPIHR-RSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLR 580 N+I+L ++ P F+DVYLV ELMD +L Q+++ L ++ Y L+Q+L Sbjct: 118 VNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQME--LDHERMSYLLYQMLS 175 Query: 581 GLKYLHSAGILHRDLKPGNLLVNANC 658 +K+LHSAGI+HRDLKP N++V ++C Sbjct: 176 AIKHLHSAGIIHRDLKPSNIVVKSDC 201
>MK08_RAT (P49185) Mitogen-activated protein kinase 8 (EC 2.7.11.24)| (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1) (SAPK gamma) (p54 gamma) Length = 411 Score = 110 bits (274), Expect = 5e-24 Identities = 57/146 (39%), Positives = 86/146 (58%), Gaps = 1/146 (0%) Frame = +2 Query: 224 FEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXX 403 F + +Y +KPIG GA GIVC++ + VAIKK++ F N+ A Sbjct: 20 FTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKC 79 Query: 404 XXXXNVIALKDIMMPIHR-RSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLR 580 N+I L ++ P F+DVY+V ELMD +L Q+++ L ++ Y L+Q+L Sbjct: 80 VNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQME--LDHERMSYLLYQMLC 137 Query: 581 GLKYLHSAGILHRDLKPGNLLVNANC 658 G+K+LHSAGI+HRDLKP N++V ++C Sbjct: 138 GIKHLHSAGIIHRDLKPSNIVVKSDC 163
>MK09_HUMAN (P45984) Mitogen-activated protein kinase 9 (EC 2.7.11.24)| (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2) (JNK-55) Length = 424 Score = 110 bits (274), Expect = 5e-24 Identities = 57/146 (39%), Positives = 86/146 (58%), Gaps = 1/146 (0%) Frame = +2 Query: 224 FEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXX 403 F + +Y +KPIG GA GIVC++ + VA+KK++ F N+ A Sbjct: 20 FTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKC 79 Query: 404 XXXXNVIALKDIMMPIHR-RSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLR 580 N+I+L ++ P F+DVYLV ELMD +L Q++ L ++ Y L+Q+L Sbjct: 80 VNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIHME--LDHERMSYLLYQMLC 137 Query: 581 GLKYLHSAGILHRDLKPGNLLVNANC 658 G+K+LHSAGI+HRDLKP N++V ++C Sbjct: 138 GIKHLHSAGIIHRDLKPSNIVVKSDC 163
>MK09_CHICK (P79996) Mitogen-activated protein kinase 9 (EC 2.7.11.24)| (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2) Length = 382 Score = 110 bits (274), Expect = 5e-24 Identities = 57/146 (39%), Positives = 86/146 (58%), Gaps = 1/146 (0%) Frame = +2 Query: 224 FEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXX 403 F + +Y +KPIG GA GIVC++ + VA+KK++ F N+ A Sbjct: 20 FTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKC 79 Query: 404 XXXXNVIALKDIMMPIHR-RSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLR 580 N+I+L ++ P F+DVYLV ELMD +L Q++ L ++ Y L+Q+L Sbjct: 80 VNHKNIISLLNVFTPQKSLEEFQDVYLVMELMDANLCQVIHME--LDHERMSYLLYQMLC 137 Query: 581 GLKYLHSAGILHRDLKPGNLLVNANC 658 G+K+LHSAGI+HRDLKP N++V ++C Sbjct: 138 GIKHLHSAGIIHRDLKPSNIVVKSDC 163
>MK09_RAT (P49186) Mitogen-activated protein kinase 9 (EC 2.7.11.24)| (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2) (SAPK-alpha) (p54-alpha) Length = 423 Score = 110 bits (274), Expect = 5e-24 Identities = 57/146 (39%), Positives = 86/146 (58%), Gaps = 1/146 (0%) Frame = +2 Query: 224 FEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXX 403 F + +Y +KPIG GA GIVC++ + VA+KK++ F N+ A Sbjct: 20 FTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKC 79 Query: 404 XXXXNVIALKDIMMPIHR-RSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLR 580 N+I+L ++ P F+DVYLV ELMD +L Q++ L ++ Y L+Q+L Sbjct: 80 VNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIHME--LDHERMSYLLYQMLC 137 Query: 581 GLKYLHSAGILHRDLKPGNLLVNANC 658 G+K+LHSAGI+HRDLKP N++V ++C Sbjct: 138 GIKHLHSAGIIHRDLKPSNIVVKSDC 163
>MK09_MOUSE (Q9WTU6) Mitogen-activated protein kinase 9 (EC 2.7.11.24)| (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2) Length = 423 Score = 110 bits (274), Expect = 5e-24 Identities = 57/146 (39%), Positives = 86/146 (58%), Gaps = 1/146 (0%) Frame = +2 Query: 224 FEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXX 403 F + +Y +KPIG GA GIVC++ + VA+KK++ F N+ A Sbjct: 20 FTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKC 79 Query: 404 XXXXNVIALKDIMMPIHR-RSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLR 580 N+I+L ++ P F+DVYLV ELMD +L Q++ L ++ Y L+Q+L Sbjct: 80 VNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIHME--LDHERMSYLLYQMLC 137 Query: 581 GLKYLHSAGILHRDLKPGNLLVNANC 658 G+K+LHSAGI+HRDLKP N++V ++C Sbjct: 138 GIKHLHSAGIIHRDLKPSNIVVKSDC 163
>MK08_MOUSE (Q91Y86) Mitogen-activated protein kinase 8 (EC 2.7.11.24)| (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1) Length = 384 Score = 110 bits (274), Expect = 5e-24 Identities = 57/146 (39%), Positives = 86/146 (58%), Gaps = 1/146 (0%) Frame = +2 Query: 224 FEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXX 403 F + +Y +KPIG GA GIVC++ + VAIKK++ F N+ A Sbjct: 20 FTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKC 79 Query: 404 XXXXNVIALKDIMMPIHR-RSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLR 580 N+I L ++ P F+DVY+V ELMD +L Q+++ L ++ Y L+Q+L Sbjct: 80 VNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQME--LDHERMSYLLYQMLC 137 Query: 581 GLKYLHSAGILHRDLKPGNLLVNANC 658 G+K+LHSAGI+HRDLKP N++V ++C Sbjct: 138 GIKHLHSAGIIHRDLKPSNIVVKSDC 163
>MK08_HUMAN (P45983) Mitogen-activated protein kinase 8 (EC 2.7.11.24)| (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1) (JNK-46) Length = 427 Score = 110 bits (274), Expect = 5e-24 Identities = 57/146 (39%), Positives = 86/146 (58%), Gaps = 1/146 (0%) Frame = +2 Query: 224 FEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXX 403 F + +Y +KPIG GA GIVC++ + VAIKK++ F N+ A Sbjct: 20 FTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKC 79 Query: 404 XXXXNVIALKDIMMPIHR-RSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLR 580 N+I L ++ P F+DVY+V ELMD +L Q+++ L ++ Y L+Q+L Sbjct: 80 VNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQME--LDHERMSYLLYQMLC 137 Query: 581 GLKYLHSAGILHRDLKPGNLLVNANC 658 G+K+LHSAGI+HRDLKP N++V ++C Sbjct: 138 GIKHLHSAGIIHRDLKPSNIVVKSDC 163
>MK08_XENLA (Q8QHK8) Mitogen-activated protein kinase 8 (EC 2.7.11.24)| (Stress-activated protein kinase JNK1) Length = 426 Score = 109 bits (273), Expect = 6e-24 Identities = 56/153 (36%), Positives = 89/153 (58%), Gaps = 1/153 (0%) Frame = +2 Query: 203 YTMWQTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXX 382 + + + F + +Y +KPIG GA GIVC++ + VAIKK++ F N+ A Sbjct: 13 FEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAFDAVLERHVAIKKLSRPFQNQTHAKRAYR 72 Query: 383 XXXXXXXXXXXNVIALKDIMMPIHR-RSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQY 559 N+I L ++ P F+D+Y+V ELMD +L Q+++ L ++ Y Sbjct: 73 ELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDLYIVMELMDANLCQVIQME--LDHERMSY 130 Query: 560 FLFQLLRGLKYLHSAGILHRDLKPGNLLVNANC 658 L+Q+L G+K+LHSAGI+HRDLKP N++V ++C Sbjct: 131 LLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDC 163
>MK08A_CYPCA (Q90327) Mitogen-activated protein kinase 8A (EC 2.7.11.24)| (Stress-activated protein kinase JNKa) (c-Jun N-terminal kinase A) Length = 427 Score = 109 bits (273), Expect = 6e-24 Identities = 59/158 (37%), Positives = 91/158 (57%), Gaps = 3/158 (1%) Frame = +2 Query: 194 KHYYTM--WQTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDA 367 K +Y++ + F + +Y ++PIG GA GIVCS+ + VAIKK++ F N+ A Sbjct: 8 KEFYSVDVGDSTFTVLKRYQNLRPIGSGAQGIVCSAYDHNLERNVAIKKLSRPFQNQTHA 67 Query: 368 XXXXXXXXXXXXXXXXNVIALKDIMMPIHRRS-FKDVYLVSELMDTDLHQIVKSSQPLSN 544 N+I L ++ F+DVYLV ELMD +L Q+++ L + Sbjct: 68 KRAYRELVLMKYVNHKNIICLLNVFTSQKTLDEFQDVYLVMELMDANLCQVIQME--LDH 125 Query: 545 DHCQYFLFQLLRGLKYLHSAGILHRDLKPGNLLVNANC 658 + Y L+Q+L G+K+LHSAGI+HRDLKP N++V ++C Sbjct: 126 ERLSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDC 163
>JNK1_ANCCA (Q9U6D2) Stress-activated protein kinase JNK-1 (EC 2.7.11.24)| Length = 376 Score = 108 bits (269), Expect = 2e-23 Identities = 59/158 (37%), Positives = 91/158 (57%), Gaps = 3/158 (1%) Frame = +2 Query: 194 KHYYTM--WQTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDA 367 ++YY + +T I +Y ++ IG GA GIVC++ + TN+ VAIKK++ F N A Sbjct: 8 ENYYVVPIGETQMVILKRYENLRLIGSGAQGIVCAATDMVTNKPVAIKKLSRPFQNVTHA 67 Query: 368 XXXXXXXXXXXXXXXXNVIALKDIMMPIHR-RSFKDVYLVSELMDTDLHQIVKSSQPLSN 544 N+I L + P F D+Y+V ELMD +L Q+++ L + Sbjct: 68 KRAYREFILMNLVNHKNIIGLLNAFSPQREVEEFNDLYIVMELMDANLCQVIQMD--LDH 125 Query: 545 DHCQYFLFQLLRGLKYLHSAGILHRDLKPGNLLVNANC 658 + Y L+Q+L G+K+LHSAGI+HRDLKP N++V ++C Sbjct: 126 ERLSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDC 163
>JNK1_CAEEL (Q8WQG9) Stress-activated protein kinase jnk-1 (EC 2.7.11.24)| Length = 463 Score = 107 bits (266), Expect = 4e-23 Identities = 57/158 (36%), Positives = 92/158 (58%), Gaps = 3/158 (1%) Frame = +2 Query: 194 KHYY--TMWQTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDA 367 ++YY T+ + + +Y ++ IG GA GIVCS+ + NE+VAIKK++ F N A Sbjct: 101 ENYYSVTIGEAQMVVLKRYQNLRLIGSGAQGIVCSAFDTVRNEQVAIKKLSRPFQNVTHA 160 Query: 368 XXXXXXXXXXXXXXXXNVIALKDIMMPIHRRS-FKDVYLVSELMDTDLHQIVKSSQPLSN 544 N+I + + P + F D+Y+V ELMD +L Q+++ L + Sbjct: 161 KRAYRELKLMSLVNHKNIIGILNCFTPQKKLDEFNDLYIVMELMDANLCQVIQMD--LDH 218 Query: 545 DHCQYFLFQLLRGLKYLHSAGILHRDLKPGNLLVNANC 658 + Y L+Q+L G+++LHSAGI+HRDLKP N++V ++C Sbjct: 219 ERLSYLLYQMLCGIRHLHSAGIIHRDLKPSNIVVRSDC 256
>MK15_HUMAN (Q8TD08) Mitogen-activated protein kinase 15 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 8) Length = 544 Score = 102 bits (254), Expect = 1e-21 Identities = 53/141 (37%), Positives = 85/141 (60%), Gaps = 1/141 (0%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXX- 415 +Y+ + +G+GAYGIV ++++ T E VAIKKI + F ++ DA Sbjct: 12 RYLLRRQLGQGAYGIVWKAVDRRTGEVVAIKKIFDAFRDKTDAQRTFREITLLQEFGDHP 71 Query: 416 NVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLRGLKYL 595 N+I+L D+ I + +D+YLV E MDTDL+ +++ L + H + +QLLR ++L Sbjct: 72 NIISLLDV---IRAENDRDIYLVFEFMDTDLNAVIRKGGLLQDVHVRSIFYQLLRATRFL 128 Query: 596 HSAGILHRDLKPGNLLVNANC 658 HS ++HRD KP N+L++ANC Sbjct: 129 HSGHVVHRDQKPSNVLLDANC 149
>KKQ1_YEAST (P36005) Probable serine/threonine-protein kinase YKL161C (EC| 2.7.11.1) Length = 433 Score = 101 bits (251), Expect = 2e-21 Identities = 57/137 (41%), Positives = 82/137 (59%), Gaps = 4/137 (2%) Frame = +2 Query: 260 IGRGAYGIVCSSINQETNEK--VAIKKINNVFDNRVDAXXXXXXXXXXXXXXXX-NVIAL 430 IGRG++ ++CSS E+NE+ VAI+KI N F N++ N++ L Sbjct: 29 IGRGSHSLICSSTYTESNEETHVAIRKIPNAFGNKLSCKRTLRELKLLRHLRGHPNIVWL 88 Query: 431 KDIMMPIHRR-SFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLRGLKYLHSAG 607 D + + + VYL ELM+ DL QI++S Q L + H Q F++Q+L LKY+HSA Sbjct: 89 FDTDIVFYPNGALNGVYLYEELMECDLSQIIRSEQRLEDAHFQSFIYQILCALKYIHSAN 148 Query: 608 ILHRDLKPGNLLVNANC 658 +LH DLKP NLLVN++C Sbjct: 149 VLHCDLKPKNLLVNSDC 165
>YPC2_CAEEL (Q11179) Putative serine/threonine-protein kinase C05D10.2 in| chromosome III (EC 2.7.11.24) Length = 470 Score = 99.4 bits (246), Expect = 9e-21 Identities = 55/144 (38%), Positives = 81/144 (56%), Gaps = 1/144 (0%) Frame = +2 Query: 230 IDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXX 409 I K+ K +G+GAYGIV + ++ + E VA+KKI + F N D+ Sbjct: 9 IHEKFDLQKRLGKGAYGIVWKAYDKRSRETVALKKIFDAFRNPTDSQRTFREVMFLQEFG 68 Query: 410 XX-NVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLRGL 586 NVI L +I + R D+YL E M+ DLH ++K L + H QY + QL R + Sbjct: 69 KHPNVIKLYNIFRADNDR---DIYLAFEFMEADLHNVIKKGSILKDVHKQYIMCQLFRAI 125 Query: 587 KYLHSAGILHRDLKPGNLLVNANC 658 ++LHS +LHRDLKP N+L++A+C Sbjct: 126 RFLHSGNVLHRDLKPSNVLLDADC 149
>MK06_RAT (P27704) Mitogen-activated protein kinase 6 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 3) (ERK-3) (p55-MAPK) Length = 720 Score = 99.0 bits (245), Expect = 1e-20 Identities = 53/151 (35%), Positives = 87/151 (57%), Gaps = 9/151 (5%) Frame = +2 Query: 224 FEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXX 403 F++ ++Y+ +KP+G G G+V S+++ + +++VAIKKI V + Sbjct: 14 FDLGSRYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKI--VLTDPQSVKHALREIKIIRR 71 Query: 404 XXXXNVIALKDIMMPIHRRSFKDV---------YLVSELMDTDLHQIVKSSQPLSNDHCQ 556 N++ + +I+ P + DV Y+V E M+TDL +++ PL +H + Sbjct: 72 LDHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQG-PLLEEHAR 130 Query: 557 YFLFQLLRGLKYLHSAGILHRDLKPGNLLVN 649 F++QLLRGLKY+HSA +LHRDLKP NL +N Sbjct: 131 LFMYQLLRGLKYIHSANVLHRDLKPANLFIN 161
>MK06_MOUSE (Q61532) Mitogen-activated protein kinase 6 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 3) (ERK-3) Length = 720 Score = 99.0 bits (245), Expect = 1e-20 Identities = 53/151 (35%), Positives = 87/151 (57%), Gaps = 9/151 (5%) Frame = +2 Query: 224 FEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXX 403 F++ ++Y+ +KP+G G G+V S+++ + +++VAIKKI V + Sbjct: 14 FDLGSRYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKI--VLTDPQSVKHALREIKIIRR 71 Query: 404 XXXXNVIALKDIMMPIHRRSFKDV---------YLVSELMDTDLHQIVKSSQPLSNDHCQ 556 N++ + +I+ P + DV Y+V E M+TDL +++ PL +H + Sbjct: 72 LDHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQG-PLLEEHAR 130 Query: 557 YFLFQLLRGLKYLHSAGILHRDLKPGNLLVN 649 F++QLLRGLKY+HSA +LHRDLKP NL +N Sbjct: 131 LFMYQLLRGLKYIHSANVLHRDLKPANLFIN 161
>MK06_HUMAN (Q16659) Mitogen-activated protein kinase 6 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 3) (ERK-3) (MAP kinase isoform p97) (p97-MAPK) Length = 721 Score = 99.0 bits (245), Expect = 1e-20 Identities = 53/151 (35%), Positives = 87/151 (57%), Gaps = 9/151 (5%) Frame = +2 Query: 224 FEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXX 403 F++ ++Y+ +KP+G G G+V S+++ + +++VAIKKI V + Sbjct: 14 FDLGSRYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKI--VLTDPQSVKHALREIKIIRR 71 Query: 404 XXXXNVIALKDIMMPIHRRSFKDV---------YLVSELMDTDLHQIVKSSQPLSNDHCQ 556 N++ + +I+ P + DV Y+V E M+TDL +++ PL +H + Sbjct: 72 LDHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQG-PLLEEHAR 130 Query: 557 YFLFQLLRGLKYLHSAGILHRDLKPGNLLVN 649 F++QLLRGLKY+HSA +LHRDLKP NL +N Sbjct: 131 LFMYQLLRGLKYIHSANVLHRDLKPANLFIN 161
>MK15_RAT (Q9Z2A6) Mitogen-activated protein kinase 15 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 7) Length = 547 Score = 97.8 bits (242), Expect = 2e-20 Identities = 52/144 (36%), Positives = 86/144 (59%), Gaps = 1/144 (0%) Frame = +2 Query: 230 IDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXX 409 + +Y+ + +G+GAYGIV ++++ T E VAIKKI + F ++ DA Sbjct: 10 VSQRYLIKRRLGKGAYGIVWKAMDRRTGEVVAIKKIFDAFRDQTDAQRTFREIMLLREFG 69 Query: 410 XX-NVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLRGL 586 N+I L D+ I ++ +D+YLV E MDTDL+ +++ + L + H + +QLLR Sbjct: 70 GHPNIIRLLDV---IPAKNDRDIYLVFESMDTDLNAVIQKGRLLEDIHKRCIFYQLLRAT 126 Query: 587 KYLHSAGILHRDLKPGNLLVNANC 658 K++HS ++HRD KP N+L++A C Sbjct: 127 KFIHSGRVIHRDQKPANVLLDAAC 150
>MK15_MOUSE (Q80Y86) Mitogen-activated protein kinase 15 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 7) Length = 549 Score = 97.1 bits (240), Expect = 4e-20 Identities = 51/141 (36%), Positives = 86/141 (60%), Gaps = 1/141 (0%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXX- 415 +Y+ + +G+GAYGIV ++++ T E VAIKKI + F +++DA Sbjct: 13 RYLIKRRLGKGAYGIVWKAMDRRTGEVVAIKKIFDAFRDQIDAQRTFREIMLLKEFGGHP 72 Query: 416 NVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLRGLKYL 595 N+I L D+ I ++ +D+YLV E MDTDL+ +++ + L + H + +QLLR K++ Sbjct: 73 NIIRLLDV---IPAKNDRDIYLVFESMDTDLNAVIQKGRLLKDIHKRCIFYQLLRATKFI 129 Query: 596 HSAGILHRDLKPGNLLVNANC 658 HS ++HRD KP N+L+++ C Sbjct: 130 HSGRVIHRDQKPANVLLDSAC 150
>SMK1_YEAST (P41808) Sporulation-specific mitogen-activated protein kinase SMK1| (EC 2.7.11.24) (MAP kinase SMK1) Length = 388 Score = 93.6 bits (231), Expect = 5e-19 Identities = 52/141 (36%), Positives = 81/141 (57%), Gaps = 3/141 (2%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSI--NQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXX 415 Y I+ +G+GAYG VCS + ++A+KKI+N+F+ + Sbjct: 38 YEIIQFLGKGAYGTVCSVKFKGRSPAARIAVKKISNIFNKEILLKRAIRELKFMNFFKGH 97 Query: 416 -NVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLRGLKY 592 N++ L D+ + + + +Y EL+D DL +++ SS LS H +YFL+Q+L GLKY Sbjct: 98 KNIVNLIDLEI-VTSSPYDGLYCYQELIDYDLAKVIHSSVQLSEFHIKYFLYQILCGLKY 156 Query: 593 LHSAGILHRDLKPGNLLVNAN 655 +HSA ++HRDLKPGN+L N Sbjct: 157 IHSADVIHRDLKPGNILCTLN 177
>MK14C_DROME (P83100) Putative mitogen-activated protein kinase 14C (EC| 2.7.11.24) (MAP kinase p38c) Length = 356 Score = 93.6 bits (231), Expect = 5e-19 Identities = 52/149 (34%), Positives = 84/149 (56%), Gaps = 2/149 (1%) Frame = +2 Query: 215 QTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXX 394 ++++E Y ++ +G G++G V + T A+K++ F+ DA Sbjct: 11 ESLWEFPDIYEFVRFLGGGSFGQVAKVRLRGTENYFAMKRLMRPFEREEDAKGTYREIRL 70 Query: 395 XXXXXXXNVIALKDIMMPI--HRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLF 568 NVI+L ++ P + F+ VYLV+ LMD DLH+ +S + +S+ + L+ Sbjct: 71 LKHMNHRNVISLLNVFHPPAHNMMEFQQVYLVTHLMDADLHRYSRSKR-MSDQEIRIILY 129 Query: 569 QLLRGLKYLHSAGILHRDLKPGNLLVNAN 655 Q+LRGLKY+HSAG++HRDLKP N+ VN N Sbjct: 130 QILRGLKYIHSAGVVHRDLKPCNIAVNGN 158
>MK04_HUMAN (P31152) Mitogen-activated protein kinase 4 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 4) (ERK-4) (MAP kinase isoform p63) (p63-MAPK) Length = 557 Score = 85.5 bits (210), Expect = 1e-16 Identities = 45/148 (30%), Positives = 80/148 (54%), Gaps = 6/148 (4%) Frame = +2 Query: 224 FEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXX 403 +++ ++V +P+G G G+V S+++ KVA+KKI + Sbjct: 14 YDLGGRFVDFQPLGFGVNGLVLSAVDSRACRKVAVKKI--ALSDARSMKHALREIKIIRR 71 Query: 404 XXXXNVIALKDIMMPIHRR------SFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFL 565 N++ + +++ P F Y+V E M+TDL ++++ L+ +H + F+ Sbjct: 72 LDHDNIVKVYEVLGPKGTDLQGELFKFSVAYIVQEYMETDLARLLEQGT-LAEEHAKLFM 130 Query: 566 FQLLRGLKYLHSAGILHRDLKPGNLLVN 649 +QLLRGLKY+HSA +LHRDLKP N+ ++ Sbjct: 131 YQLLRGLKYIHSANVLHRDLKPANIFIS 158
>MK04_MOUSE (Q6P5G0) Mitogen-activated protein kinase 4 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 4) (ERK-4) Length = 583 Score = 85.1 bits (209), Expect = 2e-16 Identities = 46/148 (31%), Positives = 79/148 (53%), Gaps = 6/148 (4%) Frame = +2 Query: 224 FEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXX 403 +++ +++ +P+G G G+V S+ + KVA+KKI V + Sbjct: 14 YDLGGRFIDFQPLGFGVNGLVLSATDSRACRKVAVKKI--VLSDARSMKHALREIKIIRR 71 Query: 404 XXXXNVIALKDIMMPIHRR------SFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFL 565 N++ + +++ P F Y+V E M+TDL +++ L+ DH + F+ Sbjct: 72 LDHDNIVKVYEVLGPKGSDLQGELFKFSVAYIVQEYMETDLACLLEQGT-LTEDHAKLFM 130 Query: 566 FQLLRGLKYLHSAGILHRDLKPGNLLVN 649 +QLLRGLKY+HSA +LHRDLKP N+ ++ Sbjct: 131 YQLLRGLKYIHSANVLHRDLKPANIFIS 158
>CDC22_ORYSA (P29619) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| Length = 292 Score = 84.3 bits (207), Expect = 3e-16 Identities = 48/138 (34%), Positives = 75/138 (54%), Gaps = 1/138 (0%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 +Y ++ IG G YG+V ++ TNE +A+KKI ++ N Sbjct: 3 QYEKVEKIGEGTYGVVYKGKHRHTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHRN 62 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHC-QYFLFQLLRGLKYL 595 ++ L+D+ +H+ K +YLV E +D DL + + SS N + FL+Q+LRG+ Y Sbjct: 63 IVRLQDV---VHKE--KCIYLVFEYLDLDLKKHMDSSPDFKNHRIVKSFLYQILRGIAYC 117 Query: 596 HSAGILHRDLKPGNLLVN 649 HS +LHRDLKP NLL++ Sbjct: 118 HSHRVLHRDLKPQNLLID 135
>CDC22_MEDSA (Q05006) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| Length = 294 Score = 83.6 bits (205), Expect = 5e-16 Identities = 48/139 (34%), Positives = 75/139 (53%), Gaps = 2/139 (1%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 +Y ++ IG G YG+V + ++ TNE +A+KKI ++ N Sbjct: 3 QYEKVEKIGEGTYGVVYKARDRATNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHRN 62 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQY--FLFQLLRGLKY 592 ++ L+D++ S K +YLV E +D DL + + SS + D Q FL+Q+L G+ Y Sbjct: 63 IVRLQDVV-----HSEKRLYLVFEYLDLDLKKFMDSSPEFAKDQRQIKMFLYQILCGIAY 117 Query: 593 LHSAGILHRDLKPGNLLVN 649 HS +LHRDLKP NLL++ Sbjct: 118 CHSHRVLHRDLKPQNLLID 136
>CDC2A_ANTMA (Q38772) Cell division control protein 2 homolog A (EC 2.7.11.22)| (EC 2.7.11.23) Length = 294 Score = 82.8 bits (203), Expect = 8e-16 Identities = 48/139 (34%), Positives = 75/139 (53%), Gaps = 2/139 (1%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 +Y ++ IG G YG+V + ++ TNE +A+KKI ++ N Sbjct: 3 QYEKVEKIGEGTYGVVYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHGN 62 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDH--CQYFLFQLLRGLKY 592 ++ L+D++ S K +YLV E +D DL + + S S D + FL+Q+LRG+ Y Sbjct: 63 IVRLQDVV-----HSEKRLYLVFEYLDLDLKKHMDSCPEFSQDPRLVKMFLYQILRGIAY 117 Query: 593 LHSAGILHRDLKPGNLLVN 649 HS +LHRDLKP NLL++ Sbjct: 118 CHSHRVLHRDLKPQNLLID 136
>PMK3_CAEEL (O44514) Mitogen-activated protein kinase pmk-3 (EC 2.7.11.24) (p38| MAP kinase 3) (Stress-activated protein kinase pmk-3) Length = 474 Score = 82.4 bits (202), Expect = 1e-15 Identities = 47/138 (34%), Positives = 72/138 (52%), Gaps = 8/138 (5%) Frame = +2 Query: 251 IKPIGRGAYGIVCSS---INQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 I+ +G G++G V + VAIKK+ F + A N+ Sbjct: 121 IEYLGGGSFGNVIKTSAVCRDGLRRYVAIKKMREPFFDPHHARRIFRETKLLQLMRHDNI 180 Query: 422 IALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQP-----LSNDHCQYFLFQLLRGL 586 I DI P F+DVY+V+E L+QI+K + L+++H ++ ++Q++R L Sbjct: 181 ICALDIYTPDEENDFRDVYVVTEFAGRSLYQILKQQRDYGRRVLTDEHIKFIIYQIIRAL 240 Query: 587 KYLHSAGILHRDLKPGNL 640 KY+HSA I+HRDLKPGNL Sbjct: 241 KYIHSANIIHRDLKPGNL 258
>CDC2A_ARATH (P24100) Cell division control protein 2 homolog A (EC 2.7.11.22)| (EC 2.7.11.23) Length = 294 Score = 82.4 bits (202), Expect = 1e-15 Identities = 47/139 (33%), Positives = 76/139 (54%), Gaps = 2/139 (1%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 +Y ++ IG G YG+V + ++ TNE +A+KKI ++ N Sbjct: 3 QYEKVEKIGEGTYGVVYKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHSN 62 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSND--HCQYFLFQLLRGLKY 592 ++ L+D++ S K +YLV E +D DL + + S+ S D + +L+Q+LRG+ Y Sbjct: 63 IVKLQDVV-----HSEKRLYLVFEYLDLDLKKHMDSTPDFSKDLHMIKTYLYQILRGIAY 117 Query: 593 LHSAGILHRDLKPGNLLVN 649 HS +LHRDLKP NLL++ Sbjct: 118 CHSHRVLHRDLKPQNLLID 136
>CDK5_MOUSE (P49615) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) (CRK6) Length = 292 Score = 81.6 bits (200), Expect = 2e-15 Identities = 51/140 (36%), Positives = 72/140 (51%), Gaps = 1/140 (0%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 KY ++ IG G YG V + N+ET+E VA+K++ D+ N Sbjct: 3 KYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKN 62 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQ-PLSNDHCQYFLFQLLRGLKYL 595 ++ L D++ S K + LV E D DL + S L + + FLFQLL+GL + Sbjct: 63 IVRLHDVL-----HSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFC 117 Query: 596 HSAGILHRDLKPGNLLVNAN 655 HS +LHRDLKP NLL+N N Sbjct: 118 HSRNVLHRDLKPQNLLINRN 137
>CDK5_HUMAN (Q00535) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) Length = 292 Score = 81.6 bits (200), Expect = 2e-15 Identities = 51/140 (36%), Positives = 72/140 (51%), Gaps = 1/140 (0%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 KY ++ IG G YG V + N+ET+E VA+K++ D+ N Sbjct: 3 KYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKN 62 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQ-PLSNDHCQYFLFQLLRGLKYL 595 ++ L D++ S K + LV E D DL + S L + + FLFQLL+GL + Sbjct: 63 IVRLHDVL-----HSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFC 117 Query: 596 HSAGILHRDLKPGNLLVNAN 655 HS +LHRDLKP NLL+N N Sbjct: 118 HSRNVLHRDLKPQNLLINRN 137
>CDK5_BOVIN (Q02399) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Proline-directed protein kinase 33 kDa subunit) (PDPK) Length = 292 Score = 81.6 bits (200), Expect = 2e-15 Identities = 51/140 (36%), Positives = 72/140 (51%), Gaps = 1/140 (0%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 KY ++ IG G YG V + N+ET+E VA+K++ D+ N Sbjct: 3 KYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKN 62 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQ-PLSNDHCQYFLFQLLRGLKYL 595 ++ L D++ S K + LV E D DL + S L + + FLFQLL+GL + Sbjct: 63 IVRLHDVL-----HSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFC 117 Query: 596 HSAGILHRDLKPGNLLVNAN 655 HS +LHRDLKP NLL+N N Sbjct: 118 HSRNVLHRDLKPQNLLINRN 137
>CDC2_CHERU (P93101) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 81.3 bits (199), Expect = 2e-15 Identities = 47/139 (33%), Positives = 75/139 (53%), Gaps = 2/139 (1%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 +Y ++ IG G YG+V + ++ TNE +A+KKI ++ N Sbjct: 3 QYEKVEKIGEGTYGVVYKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHGN 62 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDH--CQYFLFQLLRGLKY 592 ++ L+D++ S K +YLV E +D DL + + S + D + FL+Q+LRG+ Y Sbjct: 63 IVRLQDVV-----HSEKRLYLVFEYLDLDLKKHMDSCPDFAKDPRMIKRFLYQILRGIAY 117 Query: 593 LHSAGILHRDLKPGNLLVN 649 HS +LHRDLKP NLL++ Sbjct: 118 CHSHRVLHRDLKPQNLLID 136
>CDC2_VIGAC (Q41639) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 80.1 bits (196), Expect = 5e-15 Identities = 48/139 (34%), Positives = 74/139 (53%), Gaps = 2/139 (1%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 +Y ++ IG G YG+V + ++ TNE +A+KKI ++ N Sbjct: 3 QYEKVEKIGEGTYGVVYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHRN 62 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQY--FLFQLLRGLKY 592 ++ L+D++ S K +YLV E +D DL + + SS D Q FL+Q+L G+ Y Sbjct: 63 IVRLQDVV-----HSEKRLYLVFEYLDLDLKKHMDSSPEFVKDPRQVKMFLYQILCGIAY 117 Query: 593 LHSAGILHRDLKPGNLLVN 649 HS +LHRDLKP NLL++ Sbjct: 118 CHSHRVLHRDLKPQNLLID 136
>CDC2_MAIZE (P23111) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 79.3 bits (194), Expect = 9e-15 Identities = 44/139 (31%), Positives = 74/139 (53%), Gaps = 2/139 (1%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 +Y ++ IG G YG+V ++++ TNE +A+KKI ++ N Sbjct: 3 QYEKVEKIGEGTYGVVYKALDKATNETIALKKIRLEQEDEGVPSTAIREISLLKEMNHGN 62 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHC--QYFLFQLLRGLKY 592 ++ L D++ S K +YLV E +D DL + + S + + + +L+Q+L G+ Y Sbjct: 63 IVRLHDVV-----HSEKRIYLVFEYLDLDLKKFMDSCPEFAKNPTLIKSYLYQILHGVAY 117 Query: 593 LHSAGILHRDLKPGNLLVN 649 HS +LHRDLKP NLL++ Sbjct: 118 CHSHRVLHRDLKPQNLLID 136
>CDK5_RAT (Q03114) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) Length = 292 Score = 79.3 bits (194), Expect = 9e-15 Identities = 50/140 (35%), Positives = 71/140 (50%), Gaps = 1/140 (0%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 KY ++ IG G YG V + N+ET+E VA+K++ D+ N Sbjct: 3 KYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKN 62 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQ-PLSNDHCQYFLFQLLRGLKYL 595 ++ L D++ S K + LV E D DL + S L + + LFQLL+GL + Sbjct: 63 IVRLHDVL-----HSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSLLFQLLKGLGFC 117 Query: 596 HSAGILHRDLKPGNLLVNAN 655 HS +LHRDLKP NLL+N N Sbjct: 118 HSRNVLHRDLKPQNLLINRN 137
>CDK5_XENLA (P51166) Cell division protein kinase 5 (EC 2.7.11.22) (Neuronal| cyclin-dependent kinase 5) Length = 292 Score = 79.0 bits (193), Expect = 1e-14 Identities = 48/140 (34%), Positives = 72/140 (51%), Gaps = 1/140 (0%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 KY ++ IG G YG V + N++T+E VA+K++ D+ N Sbjct: 3 KYEKLEKIGEGTYGTVFKAKNRDTHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKN 62 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQ-PLSNDHCQYFLFQLLRGLKYL 595 ++ L D++ S K + LV E D DL + S L + + F++QLL+GL + Sbjct: 63 IVRLHDVL-----HSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFMYQLLKGLAFC 117 Query: 596 HSAGILHRDLKPGNLLVNAN 655 HS +LHRDLKP NLL+N N Sbjct: 118 HSRNVLHRDLKPQNLLINRN 137
>CDC21_MEDSA (P24923) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (Fragment) Length = 291 Score = 78.2 bits (191), Expect = 2e-14 Identities = 47/135 (34%), Positives = 72/135 (53%), Gaps = 2/135 (1%) Frame = +2 Query: 251 IKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNVIAL 430 ++ IG G YG+V + ++ TNE +A+KKI ++ N++ L Sbjct: 4 VEKIGEGTYGVVYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHRNIVRL 63 Query: 431 KDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQY--FLFQLLRGLKYLHSA 604 +D++ S K +YLV E +D DL + + SS D Q FL+Q+L G+ Y HS Sbjct: 64 QDVV-----HSDKRLYLVFEYLDLDLKKHMDSSPEFIKDPRQVKMFLYQMLCGIAYCHSH 118 Query: 605 GILHRDLKPGNLLVN 649 +LHRDLKP NLL++ Sbjct: 119 RVLHRDLKPQNLLID 133
>CDC2_VIGUN (P52389) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 78.2 bits (191), Expect = 2e-14 Identities = 47/139 (33%), Positives = 74/139 (53%), Gaps = 2/139 (1%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 +Y ++ IG G YG+V + ++ T+E +A+KKI ++ N Sbjct: 3 QYEKVEKIGEGTYGVVYKARDRVTDETIALKKIRLEQEDEGVPSTAIREISLLKEMQHRN 62 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQY--FLFQLLRGLKY 592 ++ L+D++ S K +YLV E +D DL + + SS D Q FL+Q+L G+ Y Sbjct: 63 IVRLQDVV-----HSEKRLYLVFEYLDLDLKKHMDSSPEFVKDPRQVKMFLYQILCGIAY 117 Query: 593 LHSAGILHRDLKPGNLLVN 649 HS +LHRDLKP NLL++ Sbjct: 118 CHSHRVLHRDLKPQNLLID 136
>CDK2_ENTHI (Q04770) Cell division protein kinase 2 homolog (EC 2.7.11.22)| Length = 291 Score = 77.8 bits (190), Expect = 3e-14 Identities = 45/140 (32%), Positives = 70/140 (50%) Frame = +2 Query: 236 TKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXX 415 T+Y + +G G YG+VC + + N VA+KKI ++ Sbjct: 2 TRYEKKQQLGEGTYGVVCKAWDTVCNRYVALKKIKQEREDDGIPVTSVREIAVLLELKHP 61 Query: 416 NVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLRGLKYL 595 NV+ L DI + K +YLV E D DL+Q + S + + + ++Q+L+GL + Sbjct: 62 NVVDLYDIYL-----EDKFLYLVFEFCDEDLYQFMSRSSKIPINETRSIVYQILQGLAFC 116 Query: 596 HSAGILHRDLKPGNLLVNAN 655 H ILHRD+KP N+L+N N Sbjct: 117 HYHQILHRDMKPQNILINKN 136
>CDC21_ORYSA (P29618) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| Length = 294 Score = 76.3 bits (186), Expect = 8e-14 Identities = 45/139 (32%), Positives = 73/139 (52%), Gaps = 2/139 (1%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 +Y + IG G YG+V + ++ TNE +A+KKI ++ N Sbjct: 3 QYEKEEKIGEGTYGVVYRARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMHHGN 62 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHC--QYFLFQLLRGLKY 592 ++ L D++ S K +YLV E +D DL + + S + + + +L+Q+LRG+ Y Sbjct: 63 IVRLHDVI-----HSEKRIYLVFEYLDLDLKKFMDSCPEFAKNPTLIKSYLYQILRGVAY 117 Query: 593 LHSAGILHRDLKPGNLLVN 649 HS +LHRDLKP NLL++ Sbjct: 118 CHSHRVLHRDLKPQNLLID 136
>CDC2B_ANTMA (Q38773) Cell division control protein 2 homolog B (EC 2.7.11.22)| (EC 2.7.11.23) (Fragment) Length = 280 Score = 76.3 bits (186), Expect = 8e-14 Identities = 48/128 (37%), Positives = 69/128 (53%), Gaps = 2/128 (1%) Frame = +2 Query: 272 AYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNVIALKDIMMPI 451 AYG+V + + ETNE +A+KKI ++ N++ LKD+ + Sbjct: 1 AYGVVYKARDIETNEDIALKKIRLEQEDEGVPSTAIREISLLKEMHHENIVNLKDV---V 57 Query: 452 HRRSFKDVYLVSELMDTDLHQIVKSSQPLSND--HCQYFLFQLLRGLKYLHSAGILHRDL 625 HR K +YLV E +D DL + + S S D + FL Q+LRG+ Y HS +LHRDL Sbjct: 58 HRE--KRLYLVFEYLDLDLKKHMDSCPEFSQDLHMVKMFLCQILRGVAYCHSHRVLHRDL 115 Query: 626 KPGNLLVN 649 KP NLL++ Sbjct: 116 KPQNLLID 123
>CDK5_DROME (P48609) Cell division protein kinase 5 homolog (EC 2.7.11.22)| Length = 294 Score = 75.9 bits (185), Expect = 1e-13 Identities = 49/140 (35%), Positives = 70/140 (50%), Gaps = 1/140 (0%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 KY ++ IG G YG V N++T E VA+K++ D+ N Sbjct: 3 KYDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELKHKN 62 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKS-SQPLSNDHCQYFLFQLLRGLKYL 595 ++ L D++ S K + LV E D DL + S + + C+ F+ QLLRGL + Sbjct: 63 IVRLIDVL-----HSDKKLTLVFEHCDQDLKKYFDSLNGEIDMAVCRSFMLQLLRGLAFC 117 Query: 596 HSAGILHRDLKPGNLLVNAN 655 HS +LHRDLKP NLL+N N Sbjct: 118 HSHNVLHRDLKPQNLLINKN 137
>CDK2_CARAU (P43450) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 75.9 bits (185), Expect = 1e-13 Identities = 49/136 (36%), Positives = 71/136 (52%), Gaps = 2/136 (1%) Frame = +2 Query: 251 IKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNVIAL 430 ++ IG G YG+V + N+ T E VA+KKI + N++ L Sbjct: 7 VEKIGEGTYGVVYKAKNKVTGETVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKL 66 Query: 431 KDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQP--LSNDHCQYFLFQLLRGLKYLHSA 604 D+ IH + +YLV E + DL + + SS +S + +LFQLL+GL + HS Sbjct: 67 HDV---IHTEN--KLYLVFEFLHQDLKRFMDSSTVTGISLPLVKSYLFQLLQGLAFCHSH 121 Query: 605 GILHRDLKPGNLLVNA 652 +LHRDLKP NLL+NA Sbjct: 122 RVLHRDLKPQNLLINA 137
>CDK2_XENLA (P23437) Cell division protein kinase 2 (EC 2.7.11.22) (CDC2| homolog Eg1 protein kinase) Length = 297 Score = 75.9 bits (185), Expect = 1e-13 Identities = 48/137 (35%), Positives = 73/137 (53%), Gaps = 2/137 (1%) Frame = +2 Query: 251 IKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNVIAL 430 ++ IG G YG+V + N+ET E VA+KKI + N++ L Sbjct: 7 VEKIGEGTYGVVYKARNRETGEIVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKL 66 Query: 431 KDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQ--PLSNDHCQYFLFQLLRGLKYLHSA 604 D+ IH + +YLV E ++ DL + + S +S + +LFQLL+GL + HS Sbjct: 67 LDV---IHTEN--KLYLVFEFLNQDLKKFMDGSNISGISLALVKSYLFQLLQGLAFCHSH 121 Query: 605 GILHRDLKPGNLLVNAN 655 +LHRDLKP NLL+N++ Sbjct: 122 RVLHRDLKPQNLLINSD 138
>MK04_RAT (Q63454) Mitogen-activated protein kinase 4 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 4) (ERK-4) (MAP kinase isoform p63) (p63-MAPK) (MNK2) (Fragment) Length = 274 Score = 75.5 bits (184), Expect = 1e-13 Identities = 44/135 (32%), Positives = 70/135 (51%), Gaps = 6/135 (4%) Frame = +2 Query: 263 GRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNVIALKDIM 442 G G G+V S+ + KVA+KKI V + N++ + +++ Sbjct: 1 GCGGNGLVLSATDSRACRKVAVKKI--VLSDARSMKHALREIKIIRRLDHDNIVKVYEVL 58 Query: 443 MPIHRR------SFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLRGLKYLHSA 604 P F Y+V E M+TDL +++ L+ +H + F++QLLRGLKY+HSA Sbjct: 59 GPKGSDLQGELFKFSVAYIVQEYMETDLACLLEQGT-LTEEHAKLFMYQLLRGLKYIHSA 117 Query: 605 GILHRDLKPGNLLVN 649 +LHRDLKP N+ ++ Sbjct: 118 NVLHRDLKPANIFIS 132
>CDC2_CHICK (P13863) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 74.7 bits (182), Expect = 2e-13 Identities = 43/139 (30%), Positives = 70/139 (50%), Gaps = 3/139 (2%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 Y I+ IG G YG+V ++ T + VA+KKI + N+ Sbjct: 4 YTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELHHPNI 63 Query: 422 IALKDIMMPIHRRSFKDVYLVSELMDTDLHQI---VKSSQPLSNDHCQYFLFQLLRGLKY 592 + L+D++M R +YL+ E + DL + + S Q L + +L+Q+L+G+ + Sbjct: 64 VCLQDVLMQDAR-----LYLIFEFLSMDLKKYLDTIPSGQYLDRSRVKSYLYQILQGIVF 118 Query: 593 LHSAGILHRDLKPGNLLVN 649 HS +LHRDLKP NLL++ Sbjct: 119 CHSRRVLHRDLKPQNLLID 137
>CDC2_RAT (P39951) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 74.7 bits (182), Expect = 2e-13 Identities = 42/139 (30%), Positives = 73/139 (52%), Gaps = 3/139 (2%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 Y+ I+ IG G YG+V ++ T + VA+KKI + N+ Sbjct: 4 YIKIEKIGEGTYGVVYKGRHRTTGQIVAMKKIRLESEEEGVPSTAIREISLLKELRHPNI 63 Query: 422 IALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQP---LSNDHCQYFLFQLLRGLKY 592 ++L+D++M R +YL+ E + DL + + S P + + + +L+Q+L+G+ + Sbjct: 64 VSLQDVLMQDSR-----LYLIFEFLSMDLKKYLDSIPPGQFMDSSLVKSYLYQILQGIVF 118 Query: 593 LHSAGILHRDLKPGNLLVN 649 HS +LHRDLKP NLL++ Sbjct: 119 CHSRRVLHRDLKPQNLLID 137
>CDC2_HUMAN (P06493) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 73.9 bits (180), Expect = 4e-13 Identities = 42/139 (30%), Positives = 72/139 (51%), Gaps = 3/139 (2%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 Y I+ IG G YG+V ++ T + VA+KKI + N+ Sbjct: 4 YTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNI 63 Query: 422 IALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQP---LSNDHCQYFLFQLLRGLKY 592 ++L+D++M R +YL+ E + DL + + S P + + + +L+Q+L+G+ + Sbjct: 64 VSLQDVLMQDSR-----LYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVF 118 Query: 593 LHSAGILHRDLKPGNLLVN 649 HS +LHRDLKP NLL++ Sbjct: 119 CHSRRVLHRDLKPQNLLID 137
>CDC2_BOVIN (P48734) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 73.9 bits (180), Expect = 4e-13 Identities = 42/139 (30%), Positives = 72/139 (51%), Gaps = 3/139 (2%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 Y I+ IG G YG+V ++ T + VA+KKI + N+ Sbjct: 4 YTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNI 63 Query: 422 IALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQP---LSNDHCQYFLFQLLRGLKY 592 ++L+D++M R +YL+ E + DL + + S P + + + +L+Q+L+G+ + Sbjct: 64 VSLQDVLMQDSR-----LYLIFEFLSMDLKKYLDSIPPGQFMDSSLVKSYLYQILQGIVF 118 Query: 593 LHSAGILHRDLKPGNLLVN 649 HS +LHRDLKP NLL++ Sbjct: 119 CHSRRVLHRDLKPQNLLID 137
>CRK1_SCHPO (Q12126) Serine/threonine-protein kinase crk1 (EC 2.7.11.23)| (Mitotic catastrophe suppressor 6) Length = 335 Score = 73.2 bits (178), Expect = 7e-13 Identities = 48/143 (33%), Positives = 74/143 (51%), Gaps = 5/143 (3%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKIN-NVFDNRVDAXXXXXXXXXXXXXXXXN 418 YV + +G G Y +V +ETN +VAIKKI F + +D N Sbjct: 11 YVKERKVGEGTYAVVFLGRQKETNRRVAIKKIKVGQFKDGIDISALREIKFLRESRHD-N 69 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSS----QPLSNDHCQYFLFQLLRGL 586 VI L D+ + ++ ++ E +D+DL ++K QP H + ++ LLRGL Sbjct: 70 VIELVDVFS-----TKSNLNIILEFLDSDLEMLIKDKFIVFQPA---HIKSWMVMLLRGL 121 Query: 587 KYLHSAGILHRDLKPGNLLVNAN 655 ++HS ILHRDLKP NLL++++ Sbjct: 122 HHIHSRFILHRDLKPNNLLISSD 144
>CDK2_MESAU (P48963) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 73.2 bits (178), Expect = 7e-13 Identities = 48/136 (35%), Positives = 71/136 (52%), Gaps = 2/136 (1%) Frame = +2 Query: 251 IKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNVIAL 430 ++ IG G YG+V + N+ T E VA+KKI + N++ L Sbjct: 7 VEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKL 66 Query: 431 KDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQP--LSNDHCQYFLFQLLRGLKYLHSA 604 D+ IH + +YLV EL+ DL + + +S + + +LFQLL+GL + HS Sbjct: 67 LDV---IHTEN--KLYLVFELLHQDLKKFMDASAVTGIPLPLIKSYLFQLLQGLAFCHSH 121 Query: 605 GILHRDLKPGNLLVNA 652 +LHRDLKP NLL+NA Sbjct: 122 RVLHRDLKPQNLLINA 137
>MDS1_YEAST (P38615) Serine/threonine-protein kinase MDS1/RIM11 (EC 2.7.11.1)| Length = 370 Score = 73.2 bits (178), Expect = 7e-13 Identities = 51/139 (36%), Positives = 73/139 (52%), Gaps = 9/139 (6%) Frame = +2 Query: 260 IGRGAYGIVCSSINQETNEKVAIKKI--NNVFDNRVDAXXXXXXXXXXXXXXXXNVIALK 433 +G G++G+V +++ QETNEKVAIKK+ + F NR N+I LK Sbjct: 45 VGHGSFGVVFATVIQETNEKVAIKKVLQDKRFKNR--------ELEIMKMLSHINIIDLK 96 Query: 434 DIMMPIHRRSFKDVY--LVSELMDTDLHQ----IVKSSQPLSNDHCQYFLFQLLRGLKYL 595 R S ++Y L+ E M L+Q V P+S +Y++FQL + L YL Sbjct: 97 YFF--YERDSQDEIYLNLILEYMPQSLYQRLRHFVHQRTPMSRLEIKYYMFQLFKSLNYL 154 Query: 596 HS-AGILHRDLKPGNLLVN 649 H A + HRD+KP NLLV+ Sbjct: 155 HHFANVCHRDIKPQNLLVD 173
>CDC2_MOUSE (P11440) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 72.8 bits (177), Expect = 9e-13 Identities = 42/139 (30%), Positives = 72/139 (51%), Gaps = 3/139 (2%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 Y+ I+ IG G YG+V ++ T + VA+KKI + N+ Sbjct: 4 YIKIEKIGEGTYGVVYKGRHRVTGQIVAMKKIRLESEEEGVPSTAIREISLLKELRHPNI 63 Query: 422 IALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQP---LSNDHCQYFLFQLLRGLKY 592 ++L+D++M R +YL+ E + DL + + S P + + + +L Q+L+G+ + Sbjct: 64 VSLQDVLMQDSR-----LYLIFEFLSMDLKKYLDSIPPGQFMDSSLVKSYLHQILQGIVF 118 Query: 593 LHSAGILHRDLKPGNLLVN 649 HS +LHRDLKP NLL++ Sbjct: 119 CHSRRVLHRDLKPQNLLID 137
>CDC15_YEAST (P27636) Cell division control protein 15 (EC 2.7.11.1)| Length = 974 Score = 72.8 bits (177), Expect = 9e-13 Identities = 46/162 (28%), Positives = 85/162 (52%), Gaps = 1/162 (0%) Frame = +2 Query: 173 NGIGNHGKHYYTMWQTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFD 352 N + + + T Q E +Y + IGRG+YG+V +IN+ T++ VAIK++ V++ Sbjct: 2 NSMADTDRVNLTPIQRASEKSVQYHLKQVIGRGSYGVVYKAINKHTDQVVAIKEV--VYE 59 Query: 353 NRVDAXXXXXXXXXXXXXXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIV-KSS 529 N + N++ + R+S++ L+ + L +++ +SS Sbjct: 60 NDEELNDIMAEISLLKNLNHNNIVKYHGFI----RKSYELYILLEYCANGSLRRLISRSS 115 Query: 530 QPLSNDHCQYFLFQLLRGLKYLHSAGILHRDLKPGNLLVNAN 655 LS + + ++ Q L GLKYLH G++HRD+K N+L++A+ Sbjct: 116 TGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSAD 157
>CDC2H_DICDI (P34117) CDC2-like serine/threonine-protein kinase CRP (EC| 2.7.11.22) (EC 2.7.11.23) Length = 292 Score = 72.8 bits (177), Expect = 9e-13 Identities = 46/138 (33%), Positives = 72/138 (52%), Gaps = 1/138 (0%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 KY I+ +G G YGIV + N+ET E VA+K+I ++ N Sbjct: 3 KYSKIEKLGEGTYGIVNKAKNRETGEIVALKRIRLDSEDEGVPCTAIREISLLKELKHPN 62 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIV-KSSQPLSNDHCQYFLFQLLRGLKYL 595 ++ L D+ IH + + LV E +D DL + + + +S + F++QLL+G+ + Sbjct: 63 IVRLHDV---IHTE--RKLTLVFEYLDQDLKKYLDECGGEISKPTIKSFMYQLLKGVAFC 117 Query: 596 HSAGILHRDLKPGNLLVN 649 H +LHRDLKP NLL+N Sbjct: 118 HDHRVLHRDLKPQNLLIN 135
>CDC28_YEAST (P00546) Cell division control protein 28 (EC 2.7.11.22)| Length = 298 Score = 72.8 bits (177), Expect = 9e-13 Identities = 47/142 (33%), Positives = 72/142 (50%), Gaps = 6/142 (4%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEK---VAIKKINNVFDNRVDAXXXXXXXXXXXXXXX 412 Y ++ +G G YG+V +++ + VA+KKI ++ Sbjct: 8 YKRLEKVGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLLKELKD 67 Query: 413 XNVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKS---SQPLSNDHCQYFLFQLLRG 583 N++ L DI +H + K +YLV E +D DL + ++ QPL D + F+ QL +G Sbjct: 68 DNIVRLYDI---VHSDAHK-LYLVFEFLDLDLKRYMEGIPKDQPLGADIVKKFMMQLCKG 123 Query: 584 LKYLHSAGILHRDLKPGNLLVN 649 + Y HS ILHRDLKP NLL+N Sbjct: 124 IAYCHSHRILHRDLKPQNLLIN 145
>CDC2C_ANTMA (Q38774) Cell division control protein 2 homolog C (EC 2.7.11.22)| (EC 2.7.11.23) Length = 305 Score = 72.8 bits (177), Expect = 9e-13 Identities = 47/145 (32%), Positives = 71/145 (48%), Gaps = 8/145 (5%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNR-VDAXXXXXXXXXXXXXXXX 415 KY ++ +G G YG V ++ + T + VA+KK D V Sbjct: 3 KYEKLEKVGEGTYGKVYKALEKSTGQVVALKKTRLEMDEEGVPPTALREVSLLQMLSQSL 62 Query: 416 NVIALKDIMMPIHRRSFKDV-YLVSELMDTDLHQIVKSSQ------PLSNDHCQYFLFQL 574 V+ L + ++ K + YLV E +DTDL + + S + PL Q FLFQL Sbjct: 63 YVVRLLSVEHVDCAKNGKPLLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPQQIQSFLFQL 122 Query: 575 LRGLKYLHSAGILHRDLKPGNLLVN 649 +G+ + H+ G+LHRDLKP NLL++ Sbjct: 123 CKGVSHCHAHGVLHRDLKPQNLLLD 147
>CDC22_XENLA (P24033) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| (EC 2.7.11.23) (p34 protein kinase 2) Length = 302 Score = 72.8 bits (177), Expect = 9e-13 Identities = 42/140 (30%), Positives = 71/140 (50%), Gaps = 3/140 (2%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 +Y I+ IG G YG+V ++ T + VA+KKI + N Sbjct: 3 EYTKIEKIGEGTYGVVYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKELQHPN 62 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMDTDLHQI---VKSSQPLSNDHCQYFLFQLLRGLK 589 ++ L D++M R +YL+ E + D+ + + S Q + + +L+Q+L+G+ Sbjct: 63 IVCLLDVLMQDSR-----LYLIFEFLSMDVKKYLDSIPSGQYIDTMLVKSYLYQILQGIV 117 Query: 590 YLHSAGILHRDLKPGNLLVN 649 + HS G+LHRDLKP NLL++ Sbjct: 118 FCHSRGVLHRDLKPQNLLID 137
>CDC2_PONPY (Q5RCH1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 72.4 bits (176), Expect = 1e-12 Identities = 41/139 (29%), Positives = 71/139 (51%), Gaps = 3/139 (2%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 Y I+ IG G YG+V ++ T + V +KKI + N+ Sbjct: 4 YTKIEKIGEGTYGVVYKGRHKTTGQVVTMKKIRLESEEEGVPSTAIREISLLKELRHPNI 63 Query: 422 IALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQP---LSNDHCQYFLFQLLRGLKY 592 ++L+D++M R +YL+ E + DL + + S P + + + +L+Q+L+G+ + Sbjct: 64 VSLQDVLMQDSR-----LYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVF 118 Query: 593 LHSAGILHRDLKPGNLLVN 649 HS +LHRDLKP NLL++ Sbjct: 119 CHSRRVLHRDLKPQNLLID 137
>CDK2_RAT (Q63699) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 72.4 bits (176), Expect = 1e-12 Identities = 48/136 (35%), Positives = 70/136 (51%), Gaps = 2/136 (1%) Frame = +2 Query: 251 IKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNVIAL 430 ++ IG G YG+V + N+ T E VA+KKI + N++ L Sbjct: 7 VEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKL 66 Query: 431 KDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQ--PLSNDHCQYFLFQLLRGLKYLHSA 604 D+ IH + +YLV E + DL + + +S L + +LFQLL+GL + HS Sbjct: 67 LDV---IHTEN--KLYLVFEFLHQDLKKFMDASALTGLPLPLIKSYLFQLLQGLAFCHSH 121 Query: 605 GILHRDLKPGNLLVNA 652 +LHRDLKP NLL+NA Sbjct: 122 RVLHRDLKPQNLLINA 137
>CDK3_HUMAN (Q00526) Cell division protein kinase 3 (EC 2.7.11.22)| Length = 305 Score = 72.4 bits (176), Expect = 1e-12 Identities = 44/135 (32%), Positives = 70/135 (51%), Gaps = 2/135 (1%) Frame = +2 Query: 251 IKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNVIAL 430 ++ IG G YG+V + N+ET + VA+KKI + N++ L Sbjct: 7 VEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKHPNIVRL 66 Query: 431 KDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSS--QPLSNDHCQYFLFQLLRGLKYLHSA 604 D+ +H + +YLV E + DL + + S+ L + +LFQLL+G+ + HS Sbjct: 67 LDV---VHNE--RKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHSH 121 Query: 605 GILHRDLKPGNLLVN 649 ++HRDLKP NLL+N Sbjct: 122 RVIHRDLKPQNLLIN 136
>CD2L7_CAEEL (P46551) Putative cell division cycle 2-related protein kinase 7| (EC 2.7.11.22) Length = 730 Score = 72.0 bits (175), Expect = 1e-12 Identities = 46/145 (31%), Positives = 70/145 (48%), Gaps = 7/145 (4%) Frame = +2 Query: 236 TKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXX 415 T Y + IG G YG V ++N T E+VA+K++ + Sbjct: 309 THYTMLDQIGEGTYGQVYKAVNNLTGEQVALKRVRLENEKEGFPITAIREIKILRQLHHK 368 Query: 416 NVIALKDIM-----MPIHRRSFKDVYLVSELMDTDLHQIVKSSQ--PLSNDHCQYFLFQL 574 N++ L DI+ M +R+ + YLV E +D DL +++S + + D QL Sbjct: 369 NIVRLMDIVIDDISMDELKRTRANFYLVFEYVDHDLIGLLESKELVDFNKDQICSLFKQL 428 Query: 575 LRGLKYLHSAGILHRDLKPGNLLVN 649 L GL Y+H+ G LHRD+K N+LVN Sbjct: 429 LEGLAYIHNTGFLHRDIKCSNILVN 453
>CDK2_BOVIN (Q5E9Y0) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 72.0 bits (175), Expect = 1e-12 Identities = 49/141 (34%), Positives = 71/141 (50%), Gaps = 6/141 (4%) Frame = +2 Query: 251 IKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNVIAL 430 ++ IG G YG+V + N+ T E VA+KKI + N++ L Sbjct: 7 VEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKL 66 Query: 431 KDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQ------PLSNDHCQYFLFQLLRGLKY 592 D+ IH + +YLV E + DL + + +S PL +LFQLL+GL + Sbjct: 67 LDV---IHTEN--KLYLVFEFLHQDLKKFMDASALTGIPLPLIKS----YLFQLLQGLAF 117 Query: 593 LHSAGILHRDLKPGNLLVNAN 655 HS +LHRDLKP NLL+NA+ Sbjct: 118 CHSHRVLHRDLKPQNLLINAD 138
>CDC2_RANDY (Q9W739) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 302 Score = 71.6 bits (174), Expect = 2e-12 Identities = 42/141 (29%), Positives = 72/141 (51%), Gaps = 3/141 (2%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 +Y I+ IG G YG+V +++ T + VA+KKI + N Sbjct: 3 EYAKIEKIGEGTYGVVYKGVHKATGQIVAMKKIRLENEEEGVPSTAIREISLLKELQHPN 62 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMDTDLHQI---VKSSQPLSNDHCQYFLFQLLRGLK 589 ++ L D++M R +YL+ E + DL + + S Q L + +L+Q+L+G+ Sbjct: 63 IVCLLDVLMQDSR-----LYLIFEFLSMDLKKYLDSIPSGQYLEAMLVKSYLYQILQGII 117 Query: 590 YLHSAGILHRDLKPGNLLVNA 652 + H+ +LHRDLKP NLL+++ Sbjct: 118 FCHARRVLHRDLKPQNLLIDS 138
>MHK_ARATH (P43294) Serine/threonine-protein kinase MHK (EC 2.7.11.22)| Length = 443 Score = 71.6 bits (174), Expect = 2e-12 Identities = 45/140 (32%), Positives = 72/140 (51%), Gaps = 1/140 (0%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 +Y ++ +G G G V ++N ET E VA+KK+ F + + Sbjct: 11 RYKILEELGDGTCGSVYKAVNLETYEVVAVKKMKRKFYYWEECVNLREVKALRKLNHP-H 69 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQ-PLSNDHCQYFLFQLLRGLKYL 595 +I LK+I+ R +++ + E MD +L+ I+K + P S + F+ Q+L+GL ++ Sbjct: 70 IIKLKEIV-----REHNELFFIFECMDHNLYHIMKERERPFSEGEIRSFMSQMLQGLAHM 124 Query: 596 HSAGILHRDLKPGNLLVNAN 655 H G HRDLKP NLLV N Sbjct: 125 HKNGYFHRDLKPENLLVTNN 144
>CDK2_CRIGR (O55076) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 71.6 bits (174), Expect = 2e-12 Identities = 47/136 (34%), Positives = 70/136 (51%), Gaps = 2/136 (1%) Frame = +2 Query: 251 IKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNVIAL 430 ++ IG G YG+V + N+ T E VA+KKI + N++ L Sbjct: 7 VEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKL 66 Query: 431 KDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQP--LSNDHCQYFLFQLLRGLKYLHSA 604 D+ IH + +YLV E + DL + + +S + + +LFQLL+GL + HS Sbjct: 67 LDV---IHTEN--KLYLVFEFLHQDLKKFMDASAVTGIPLPLIKSYLFQLLQGLAFCHSH 121 Query: 605 GILHRDLKPGNLLVNA 652 +LHRDLKP NLL+NA Sbjct: 122 RVLHRDLKPQNLLINA 137
>CDK2_MOUSE (P97377) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 346 Score = 71.6 bits (174), Expect = 2e-12 Identities = 49/140 (35%), Positives = 70/140 (50%), Gaps = 6/140 (4%) Frame = +2 Query: 251 IKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNVIAL 430 ++ IG G YG+V + N+ T E VA+KKI + N++ L Sbjct: 7 VEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKL 66 Query: 431 KDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQ------PLSNDHCQYFLFQLLRGLKY 592 D+ IH + +YLV E + DL + + +S PL +LFQLL+GL + Sbjct: 67 LDV---IHTEN--KLYLVFEFLHQDLKKFMDASALTGIPLPLIKS----YLFQLLQGLAF 117 Query: 593 LHSAGILHRDLKPGNLLVNA 652 HS +LHRDLKP NLL+NA Sbjct: 118 CHSHRVLHRDLKPQNLLINA 137
>PCTK1_HUMAN (Q00536) Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 1) Length = 496 Score = 71.2 bits (173), Expect = 3e-12 Identities = 48/137 (35%), Positives = 66/137 (48%), Gaps = 1/137 (0%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 Y+ + +G G Y V ++ T+ VA+K+I + N+ Sbjct: 165 YIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHA-NI 223 Query: 422 IALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDH-CQYFLFQLLRGLKYLH 598 + L DI IH K + LV E +D DL Q + + N H + FLFQLLRGL Y H Sbjct: 224 VTLHDI---IHTE--KSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCH 278 Query: 599 SAGILHRDLKPGNLLVN 649 +LHRDLKP NLL+N Sbjct: 279 RQKVLHRDLKPQNLLIN 295
>CTK1_YEAST (Q03957) CTD kinase subunit alpha (EC 2.7.11.23) (CTD kinase 58 kDa| subunit) (CTDK-I alpha subunit) Length = 528 Score = 71.2 bits (173), Expect = 3e-12 Identities = 43/137 (31%), Positives = 69/137 (50%), Gaps = 1/137 (0%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 Y+ I +G G YG V + N T + VA+KK+ + NV Sbjct: 183 YLRIMQVGEGTYGKVYKAKNTNTEKLVALKKLRLQGEREGFPITSIREIKLLQSFDHPNV 242 Query: 422 IALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQ-PLSNDHCQYFLFQLLRGLKYLH 598 +K+IM+ S K VY++ E D DL ++ + + +S+ C++ QLL G++YLH Sbjct: 243 STIKEIMV----ESQKTVYMIFEYADNDLSGLLLNKEVQISHSQCKHLFKQLLLGMEYLH 298 Query: 599 SAGILHRDLKPGNLLVN 649 ILHRD+K N+L++ Sbjct: 299 DNKILHRDVKGSNILID 315
>CDC21_XENLA (P35567) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (p34 protein kinase 1) Length = 302 Score = 71.2 bits (173), Expect = 3e-12 Identities = 42/141 (29%), Positives = 71/141 (50%), Gaps = 3/141 (2%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 +Y I+ IG G YG+V ++ T + VA+KKI + N Sbjct: 3 EYTKIEKIGEGTYGVVYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKELQHPN 62 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMDTDLHQI---VKSSQPLSNDHCQYFLFQLLRGLK 589 ++ L D++M R +YL+ E + DL + + S Q + + +L+Q+L+G+ Sbjct: 63 IVCLLDVLMQDSR-----LYLIFEFLSMDLKKYLDSIPSGQYIDTMLVKSYLYQILQGIV 117 Query: 590 YLHSAGILHRDLKPGNLLVNA 652 + HS +LHRDLKP NLL+++ Sbjct: 118 FCHSRRVLHRDLKPQNLLIDS 138
>PCTK1_RAT (Q63686) Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 1) Length = 496 Score = 70.9 bits (172), Expect = 3e-12 Identities = 48/137 (35%), Positives = 66/137 (48%), Gaps = 1/137 (0%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 Y+ + +G G Y V ++ T+ VA+K+I + N+ Sbjct: 165 YIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHA-NI 223 Query: 422 IALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDH-CQYFLFQLLRGLKYLH 598 + L DI IH K + LV E +D DL Q + + N H + FLFQLLRGL Y H Sbjct: 224 VTLHDI---IHTE--KSLTLVFEYLDKDLKQYLDDCGNVINMHNVKLFLFQLLRGLAYCH 278 Query: 599 SAGILHRDLKPGNLLVN 649 +LHRDLKP NLL+N Sbjct: 279 RQKVLHRDLKPQNLLIN 295
>PCTK1_MOUSE (Q04735) Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 1) (CRK5) Length = 496 Score = 70.9 bits (172), Expect = 3e-12 Identities = 48/137 (35%), Positives = 66/137 (48%), Gaps = 1/137 (0%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 Y+ + +G G Y V ++ T+ VA+K+I + N+ Sbjct: 165 YIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHA-NI 223 Query: 422 IALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDH-CQYFLFQLLRGLKYLH 598 + L DI IH K + LV E +D DL Q + + N H + FLFQLLRGL Y H Sbjct: 224 VTLHDI---IHTE--KSLTLVFEYLDKDLKQYLDDCGNVINMHNVKLFLFQLLRGLAYCH 278 Query: 599 SAGILHRDLKPGNLLVN 649 +LHRDLKP NLL+N Sbjct: 279 RQKVLHRDLKPQNLLIN 295
>PCTK3_RAT (O35832) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 451 Score = 70.1 bits (170), Expect = 6e-12 Identities = 46/137 (33%), Positives = 66/137 (48%), Gaps = 1/137 (0%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 YV + +G G Y V ++ T VA+K+I + N+ Sbjct: 121 YVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHA-NI 179 Query: 422 IALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDH-CQYFLFQLLRGLKYLH 598 + L D++ + + + LV E +D+DL Q + L N H + F+FQLLRGL Y H Sbjct: 180 VTLHDLI-----HTDRSLTLVFEYLDSDLKQYLDHCGNLMNMHNVKIFMFQLLRGLAYCH 234 Query: 599 SAGILHRDLKPGNLLVN 649 ILHRDLKP NLL+N Sbjct: 235 RRKILHRDLKPQNLLIN 251
>PCTK3_MOUSE (Q04899) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 451 Score = 70.1 bits (170), Expect = 6e-12 Identities = 46/137 (33%), Positives = 66/137 (48%), Gaps = 1/137 (0%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 YV + +G G Y V ++ T VA+K+I + N+ Sbjct: 121 YVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHA-NI 179 Query: 422 IALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDH-CQYFLFQLLRGLKYLH 598 + L D++ + + + LV E +D+DL Q + L N H + F+FQLLRGL Y H Sbjct: 180 VTLHDLI-----HTDRSLTLVFEYLDSDLKQYLDHCGNLMNMHNVKIFMFQLLRGLAYCH 234 Query: 599 SAGILHRDLKPGNLLVN 649 ILHRDLKP NLL+N Sbjct: 235 HRKILHRDLKPQNLLIN 251
>CDK2_HUMAN (P24941) Cell division protein kinase 2 (EC 2.7.11.22) (p33 protein| kinase) Length = 298 Score = 70.1 bits (170), Expect = 6e-12 Identities = 48/139 (34%), Positives = 69/139 (49%), Gaps = 6/139 (4%) Frame = +2 Query: 251 IKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNVIAL 430 ++ IG G YG+V + N+ T E VA+KKI + N++ L Sbjct: 7 VEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKL 66 Query: 431 KDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQ------PLSNDHCQYFLFQLLRGLKY 592 D+ IH + +YLV E + DL + + +S PL +LFQLL+GL + Sbjct: 67 LDV---IHTEN--KLYLVFEFLHQDLKKFMDASALTGIPLPLIKS----YLFQLLQGLAF 117 Query: 593 LHSAGILHRDLKPGNLLVN 649 HS +LHRDLKP NLL+N Sbjct: 118 CHSHRVLHRDLKPQNLLIN 136
>CDC2_DICDI (P34112) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 296 Score = 70.1 bits (170), Expect = 6e-12 Identities = 47/138 (34%), Positives = 73/138 (52%) Frame = +2 Query: 236 TKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXX 415 ++Y ++ +G G YG V + + T VA+KKI + D+ V + Sbjct: 8 SRYQKLEKLGEGTYGKVYKAKEKATGRMVALKKIR-LEDDGVPSTALREISLLKEVPHP- 65 Query: 416 NVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLRGLKYL 595 NV++L D++ +R +YLV E +D DL + + S L + +L+QLL+GL Y Sbjct: 66 NVVSLFDVLHCQNR-----LYLVFEYLDQDLKKYMDSVPALCPQLIKSYLYQLLKGLAYS 120 Query: 596 HSAGILHRDLKPGNLLVN 649 H ILHRDLKP NLL++ Sbjct: 121 HGHRILHRDLKPQNLLID 138
>CDC28_CANAL (P43063) Cell division control protein 28 (EC 2.7.11.22)| Length = 317 Score = 69.7 bits (169), Expect = 7e-12 Identities = 46/134 (34%), Positives = 72/134 (53%), Gaps = 4/134 (2%) Frame = +2 Query: 260 IGRGAYGIVCSSINQETNEKV-AIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNVIALKD 436 +G G YG+V +++ + N +V A+KKI ++ N++ L D Sbjct: 13 VGEGTYGVVYKALDTKHNNRVVALKKIRLESEDEGVPSTAIREISLLKEMKDDNIVRLYD 72 Query: 437 IMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQP---LSNDHCQYFLFQLLRGLKYLHSAG 607 I IH S K +YLV E +D DL + ++S L + + F+ QL+RG+K+ HS Sbjct: 73 I---IHSDSHK-LYLVFEFLDLDLKKYMESIPQGVGLGANMIKRFMNQLIRGIKHCHSHR 128 Query: 608 ILHRDLKPGNLLVN 649 +LHRDLKP NLL++ Sbjct: 129 VLHRDLKPQNLLID 142
>CDC2_ORYLU (Q9DG98) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 69.7 bits (169), Expect = 7e-12 Identities = 43/139 (30%), Positives = 68/139 (48%), Gaps = 3/139 (2%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 YV I+ IG G YG+V ++ T + VA+KKI + NV Sbjct: 4 YVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHPNV 63 Query: 422 IALKDIMMPIHRRSFKDVYLVSELMDTDLHQI---VKSSQPLSNDHCQYFLFQLLRGLKY 592 + L D++M R +YL+ E + DL + + S Q + + +L+Q+L G+ + Sbjct: 64 VRLLDVLMQESR-----LYLIFEFLSMDLKKYLDSIPSGQYMDPMLVKSYLYQILEGIYF 118 Query: 593 LHSAGILHRDLKPGNLLVN 649 H +LHRDLKP NLL++ Sbjct: 119 CHRRRVLHRDLKPQNLLID 137
>CDC2_ORYLA (Q9DGD3) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 69.7 bits (169), Expect = 7e-12 Identities = 43/139 (30%), Positives = 68/139 (48%), Gaps = 3/139 (2%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 YV I+ IG G YG+V ++ T + VA+KKI + NV Sbjct: 4 YVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHPNV 63 Query: 422 IALKDIMMPIHRRSFKDVYLVSELMDTDLHQI---VKSSQPLSNDHCQYFLFQLLRGLKY 592 + L D++M R +YL+ E + DL + + S Q + + +L+Q+L G+ + Sbjct: 64 VRLLDVLMQESR-----LYLIFEFLSMDLKKYLDSIPSGQYMDPMLVKSYLYQILEGIYF 118 Query: 593 LHSAGILHRDLKPGNLLVN 649 H +LHRDLKP NLL++ Sbjct: 119 CHRRRVLHRDLKPQNLLID 137
>CDC2_ORYJA (Q9DGA2) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 69.7 bits (169), Expect = 7e-12 Identities = 43/139 (30%), Positives = 68/139 (48%), Gaps = 3/139 (2%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 YV I+ IG G YG+V ++ T + VA+KKI + NV Sbjct: 4 YVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHPNV 63 Query: 422 IALKDIMMPIHRRSFKDVYLVSELMDTDLHQI---VKSSQPLSNDHCQYFLFQLLRGLKY 592 + L D++M R +YL+ E + DL + + S Q + + +L+Q+L G+ + Sbjct: 64 VRLLDVLMQESR-----LYLIFEFLSMDLKKYLDSIPSGQYMDPMLVKSYLYQILEGIYF 118 Query: 593 LHSAGILHRDLKPGNLLVN 649 H +LHRDLKP NLL++ Sbjct: 119 CHRRRVLHRDLKPQNLLID 137
>CDC2_ORYCU (Q9DGA5) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 69.7 bits (169), Expect = 7e-12 Identities = 43/139 (30%), Positives = 68/139 (48%), Gaps = 3/139 (2%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 YV I+ IG G YG+V ++ T + VA+KKI + NV Sbjct: 4 YVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHPNV 63 Query: 422 IALKDIMMPIHRRSFKDVYLVSELMDTDLHQI---VKSSQPLSNDHCQYFLFQLLRGLKY 592 + L D++M R +YL+ E + DL + + S Q + + +L+Q+L G+ + Sbjct: 64 VRLLDVLMQESR-----LYLIFEFLSMDLKKYLDSIPSGQYMDPMLVKSYLYQILEGIYF 118 Query: 593 LHSAGILHRDLKPGNLLVN 649 H +LHRDLKP NLL++ Sbjct: 119 CHRRRVLHRDLKPQNLLID 137
>CDC2_CARAU (P51958) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 302 Score = 68.9 bits (167), Expect = 1e-11 Identities = 43/139 (30%), Positives = 68/139 (48%), Gaps = 3/139 (2%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 Y+ I+ IG G YG+V N+ T + VA+KKI + NV Sbjct: 4 YLKIEKIGEGTYGVVYKGRNKTTGQVVAMKKIRLESEEEGVPSTAVREISLLKELQHPNV 63 Query: 422 IALKDIMMPIHRRSFKDVYLVSELMDTDLHQI---VKSSQPLSNDHCQYFLFQLLRGLKY 592 + L D++M + +YLV E + DL + + S Q + + +L+Q+L G+ + Sbjct: 64 VRLLDVLMQESK-----LYLVFEFLSMDLKKYLDSIPSGQFMDPMLVKSYLYQILEGILF 118 Query: 593 LHSAGILHRDLKPGNLLVN 649 H +LHRDLKP NLL++ Sbjct: 119 CHCRRVLHRDLKPQNLLID 137
>PIT1_SCHPO (O14132) Sporulation protein kinase pit1 (EC 2.7.11.1)| Length = 650 Score = 68.9 bits (167), Expect = 1e-11 Identities = 38/145 (26%), Positives = 75/145 (51%), Gaps = 3/145 (2%) Frame = +2 Query: 230 IDTKYVPIKPIGRGAYGIV-CSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXX 406 ID Y ++ +G G +G V ++ + E VAIK + DA Sbjct: 32 IDEVYNVVRKVGDGTFGSVYLATTKTPSKEVVAIKSMKKKLAKVSDATRLREVHSLLRLS 91 Query: 407 XXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIV--KSSQPLSNDHCQYFLFQLLR 580 N++ + D+ + F+ +++V E +D +L+Q++ + + PL+ + Q + Q+ + Sbjct: 92 ENENIVNIFDLYID----QFRCLHIVMEFLDCNLYQLISTRKNDPLTLEQVQDIMRQIFK 147 Query: 581 GLKYLHSAGILHRDLKPGNLLVNAN 655 GL ++H+ G HRD+KP N+L+++N Sbjct: 148 GLNHIHTNGFFHRDMKPENILISSN 172
>CDC2D_ANTMA (Q38775) Cell division control protein 2 homolog D (EC 2.7.11.22)| (EC 2.7.11.23) Length = 312 Score = 68.9 bits (167), Expect = 1e-11 Identities = 41/141 (29%), Positives = 72/141 (51%), Gaps = 5/141 (3%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNR-VDAXXXXXXXXXXXXXXXXN 418 +V ++ +G G YG V ++ + T + VA+KK D V + Sbjct: 14 FVKLEKVGEGTYGKVYRAMEKSTGKIVALKKTRLHEDEEGVPPTTLREVSLLRMLSRDPH 73 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKS----SQPLSNDHCQYFLFQLLRGL 586 V+ L D+ ++ +YLV E MDTDL + ++S + ++ + + ++QL +G+ Sbjct: 74 VVRLLDVKQGQNKEGKTVLYLVFEYMDTDLKKYIRSFKQTGESIAPMNVKSLMYQLCKGV 133 Query: 587 KYLHSAGILHRDLKPGNLLVN 649 + H G+LHRDLKP NLL++ Sbjct: 134 AFCHGHGVLHRDLKPHNLLMD 154
>PCTK3_PONPY (Q5RD01) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 472 Score = 68.2 bits (165), Expect = 2e-11 Identities = 45/137 (32%), Positives = 66/137 (48%), Gaps = 1/137 (0%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 YV + +G G Y V ++ T VA+K+I + N+ Sbjct: 142 YVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKNLKHA-NI 200 Query: 422 IALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDH-CQYFLFQLLRGLKYLH 598 + L D++ + + + LV E +D+DL Q + L + H + F+FQLLRGL Y H Sbjct: 201 VTLHDLI-----HTDRSLTLVFEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCH 255 Query: 599 SAGILHRDLKPGNLLVN 649 ILHRDLKP NLL+N Sbjct: 256 HRKILHRDLKPQNLLIN 272
>PCTK2_RAT (O35831) Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 2) Length = 523 Score = 68.2 bits (165), Expect = 2e-11 Identities = 43/137 (31%), Positives = 66/137 (48%), Gaps = 1/137 (0%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 Y+ ++ +G G Y V ++ T VA+K+I + N+ Sbjct: 192 YIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHA-NI 250 Query: 422 IALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDH-CQYFLFQLLRGLKYLH 598 + L DI+ + K + LV E +D DL Q + + + H + FL+Q+LRGL Y H Sbjct: 251 VTLHDIV-----HTDKSLTLVFEYLDKDLKQYMDDCGSIMSMHNVKLFLYQILRGLAYCH 305 Query: 599 SAGILHRDLKPGNLLVN 649 +LHRDLKP NLL+N Sbjct: 306 RRKVLHRDLKPQNLLIN 322
>CDC2H_PLAYO (Q7RM49) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 289 Score = 67.8 bits (164), Expect = 3e-11 Identities = 47/139 (33%), Positives = 69/139 (49%), Gaps = 2/139 (1%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKIN-NVFDNRVDAXXXXXXXXXXXXXXXX 415 KY ++ IG G YG+V + N + E A+KKI D + + Sbjct: 3 KYHGLEKIGEGTYGVVYKAQNSD-GESFALKKIRLEKEDEGIPSTVSIREISILKELRHS 61 Query: 416 NVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQP-LSNDHCQYFLFQLLRGLKY 592 N++ L D+ IH + K + LV E +D DL +++ L + + FL QLL G+ Y Sbjct: 62 NIVKLYDV---IHAK--KRLILVFEHLDQDLKKLIDVCDGGLESVTAKSFLLQLLNGIAY 116 Query: 593 LHSAGILHRDLKPGNLLVN 649 H +LHRDLKP NLL+N Sbjct: 117 CHEHRVLHRDLKPQNLLIN 135
>ICK_RAT (Q62726) Serine/threonine-protein kinase ICK (EC 2.7.11.22)| (Intestinal cell kinase) (MAK-related kinase) (MRK) Length = 629 Score = 67.8 bits (164), Expect = 3e-11 Identities = 41/136 (30%), Positives = 68/136 (50%), Gaps = 1/136 (0%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 +Y IK +G G YG V + E+ E +AIKK+ F + + N Sbjct: 3 RYTTIKQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHA-N 61 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHC-QYFLFQLLRGLKYL 595 ++ LK+++ R +Y + E M +L+Q++K L + + ++Q+L+GL ++ Sbjct: 62 IVKLKEVI-----RENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFI 116 Query: 596 HSAGILHRDLKPGNLL 643 H G HRDLKP NLL Sbjct: 117 HKHGFFHRDLKPENLL 132
>ICK_MOUSE (Q9JKV2) Serine/threonine-protein kinase ICK (EC 2.7.11.22)| (Intestinal cell kinase) (mICK) (MAK-related kinase) (MRK) Length = 629 Score = 67.8 bits (164), Expect = 3e-11 Identities = 41/136 (30%), Positives = 68/136 (50%), Gaps = 1/136 (0%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 +Y IK +G G YG V + E+ E +AIKK+ F + + N Sbjct: 3 RYTTIKQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHA-N 61 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHC-QYFLFQLLRGLKYL 595 ++ LK+++ R +Y + E M +L+Q++K L + + ++Q+L+GL ++ Sbjct: 62 IVKLKEVI-----RENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFI 116 Query: 596 HSAGILHRDLKPGNLL 643 H G HRDLKP NLL Sbjct: 117 HKHGFFHRDLKPENLL 132
>CDC2B_ARATH (P25859) Cell division control protein 2 homolog B (EC 2.7.11.22)| (EC 2.7.11.23) Length = 309 Score = 67.8 bits (164), Expect = 3e-11 Identities = 45/148 (30%), Positives = 69/148 (46%), Gaps = 12/148 (8%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 KY ++ +G G YG V ++ + T + VA+KK D Sbjct: 3 KYEKLEKVGEGTYGKVYKAMEKGTGKLVALKKTRLEMDEEGIPPTALREISLLQMLSTSI 62 Query: 419 VIALKDIMMPIHRRSFK------DVYLVSELMDTDLHQIVKS------SQPLSNDHCQYF 562 + + +H+ S K ++YLV E +DTDL + + S +PL Q Sbjct: 63 YVVRLLCVEHVHQPSTKSQSTKSNLYLVFEYLDTDLKKFIDSYRKGPNPKPLEPFLIQKL 122 Query: 563 LFQLLRGLKYLHSAGILHRDLKPGNLLV 646 +FQL +G+ + HS G+LHRDLKP NLL+ Sbjct: 123 MFQLCKGVAHCHSHGVLHRDLKPQNLLL 150
>MAK_MOUSE (Q04859) Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male| germ cell-associated kinase) (Protein kinase RCK) Length = 622 Score = 67.8 bits (164), Expect = 3e-11 Identities = 43/136 (31%), Positives = 68/136 (50%), Gaps = 1/136 (0%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 +Y +K +G G YG V + E+ E VAIK++ F + D N Sbjct: 3 RYTTMKQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSW-DECMNLREVKSLKKLNHAN 61 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHC-QYFLFQLLRGLKYL 595 VI LK+++ R +Y V E M +L+Q++K L + + ++Q+L+GL ++ Sbjct: 62 VIKLKEVI-----RENDHLYFVFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFI 116 Query: 596 HSAGILHRDLKPGNLL 643 H G HRD+KP NLL Sbjct: 117 HKHGFFHRDMKPENLL 132
>PCTK2_MOUSE (Q8K0D0) Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 2) Length = 523 Score = 67.8 bits (164), Expect = 3e-11 Identities = 43/137 (31%), Positives = 66/137 (48%), Gaps = 1/137 (0%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 Y+ ++ +G G Y V ++ T VA+K+I + N+ Sbjct: 192 YIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHA-NI 250 Query: 422 IALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDH-CQYFLFQLLRGLKYLH 598 + L DI+ + K + LV E +D DL Q + + + H + FL+Q+LRGL Y H Sbjct: 251 VTLHDIV-----HTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRGLAYCH 305 Query: 599 SAGILHRDLKPGNLLVN 649 +LHRDLKP NLL+N Sbjct: 306 RRKVLHRDLKPQNLLIN 322
>PCTK2_HUMAN (Q00537) Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 2) Length = 523 Score = 67.8 bits (164), Expect = 3e-11 Identities = 43/137 (31%), Positives = 66/137 (48%), Gaps = 1/137 (0%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 Y+ ++ +G G Y V ++ T VA+K+I + N+ Sbjct: 192 YIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHA-NI 250 Query: 422 IALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDH-CQYFLFQLLRGLKYLH 598 + L DI+ + K + LV E +D DL Q + + + H + FL+Q+LRGL Y H Sbjct: 251 VTLHDIV-----HTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRGLAYCH 305 Query: 599 SAGILHRDLKPGNLLVN 649 +LHRDLKP NLL+N Sbjct: 306 RRKVLHRDLKPQNLLIN 322
>CDC2_DROME (P23572) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 297 Score = 67.8 bits (164), Expect = 3e-11 Identities = 39/136 (28%), Positives = 69/136 (50%), Gaps = 3/136 (2%) Frame = +2 Query: 251 IKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNVIAL 430 I+ IG G YG+V N+ T + VA+KKI D+ N++ L Sbjct: 7 IEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKHENIVCL 66 Query: 431 KDIMMPIHRRSFKDVYLVSELMDTDLHQIVKS---SQPLSNDHCQYFLFQLLRGLKYLHS 601 +D++M +R +YL+ E + DL + + S + + ++ + +L+Q+ + + H Sbjct: 67 EDVLMEENR-----IYLIFEFLSMDLKKYMDSLPVDKHMESELVRSYLYQITSAILFCHR 121 Query: 602 AGILHRDLKPGNLLVN 649 +LHRDLKP NLL++ Sbjct: 122 RRVLHRDLKPQNLLID 137
>CDC2H_PLACH (Q4Y4B1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 67.4 bits (163), Expect = 4e-11 Identities = 46/138 (33%), Positives = 68/138 (49%), Gaps = 1/138 (0%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 KY ++ IG G YG+V + N + E A+KKI ++ N Sbjct: 3 KYHGLEKIGEGTYGVVYKAQNSD-GESFALKKIRLEKEDEGIPSTAIREISILKELRHSN 61 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQP-LSNDHCQYFLFQLLRGLKYL 595 ++ L D+ IH + K + LV E +D DL +++ L + + FL QLL G+ Y Sbjct: 62 IVKLYDV---IHAK--KRLILVFEHLDQDLKKLIDVCDGGLESVTAKSFLLQLLNGIAYC 116 Query: 596 HSAGILHRDLKPGNLLVN 649 H +LHRDLKP NLL+N Sbjct: 117 HEHRVLHRDLKPQNLLIN 134
>CDC2H_PLABA (Q4Z6R1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 67.4 bits (163), Expect = 4e-11 Identities = 46/138 (33%), Positives = 68/138 (49%), Gaps = 1/138 (0%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 KY ++ IG G YG+V + N + E A+KKI ++ N Sbjct: 3 KYHGLEKIGEGTYGVVYKAQNSD-GESFALKKIRLEKEDEGIPSTAIREISILKELRHSN 61 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQP-LSNDHCQYFLFQLLRGLKYL 595 ++ L D+ IH + K + LV E +D DL +++ L + + FL QLL G+ Y Sbjct: 62 IVKLYDV---IHAK--KRLILVFEHLDQDLKKLIDVCDGGLESVTAKSFLLQLLNGIAYC 116 Query: 596 HSAGILHRDLKPGNLLVN 649 H +LHRDLKP NLL+N Sbjct: 117 HEHRVLHRDLKPQNLLIN 134
>PHO85_YARLI (Q6C7U8) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 294 Score = 67.4 bits (163), Expect = 4e-11 Identities = 43/142 (30%), Positives = 71/142 (50%), Gaps = 3/142 (2%) Frame = +2 Query: 236 TKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXX 415 +++ ++ +G G Y V N+ T + VA+K+IN + Sbjct: 5 SQFQQLEKLGEGTYATVYKGRNRTTGQLVALKEIN-LDSEEGTPSTAIREISLMKELKHE 63 Query: 416 NVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQ---PLSNDHCQYFLFQLLRGL 586 N++ L D+ IH + + LV E MD DL + + ++ L ++F++QLLRG+ Sbjct: 64 NIVTLYDV---IHTEN--KLNLVFEYMDKDLKKFMDTNGNKGALETKQVKWFMYQLLRGI 118 Query: 587 KYLHSAGILHRDLKPGNLLVNA 652 + H +LHRDLKP NLL+NA Sbjct: 119 LFCHDNRVLHRDLKPQNLLINA 140
>CDC2H_THEPA (Q27032) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 298 Score = 67.4 bits (163), Expect = 4e-11 Identities = 45/138 (32%), Positives = 69/138 (50%), Gaps = 1/138 (0%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 +Y ++ IG G YG+V + N E A+KKI ++ N Sbjct: 3 RYHKMEKIGEGTYGVVYKAQNNH-GEICALKKIRVEEEDEGIPSTAIREISLLKELHHPN 61 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQP-LSNDHCQYFLFQLLRGLKYL 595 ++ L+D++ S K + LV E +D DL +++ + L + FL+Q+LRG+ Y Sbjct: 62 IVWLRDVI-----HSEKCLTLVFEYLDQDLKKLLDACDGGLEPTTAKSFLYQILRGISYC 116 Query: 596 HSAGILHRDLKPGNLLVN 649 H ILHRDLKP NLL+N Sbjct: 117 HDHRILHRDLKPQNLLIN 134
>CDC2H_THEAN (Q26671) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 298 Score = 67.4 bits (163), Expect = 4e-11 Identities = 45/138 (32%), Positives = 69/138 (50%), Gaps = 1/138 (0%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 +Y ++ IG G YG+V + N E A+KKI ++ N Sbjct: 3 RYHKMEKIGEGTYGVVYKAQNNH-GEICALKKIRVEEEDEGIPSTAIREISLLKELHHPN 61 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQP-LSNDHCQYFLFQLLRGLKYL 595 ++ L+D++ S K + LV E +D DL +++ + L + FL+Q+LRG+ Y Sbjct: 62 IVWLRDVI-----HSEKCLTLVFEYLDQDLKKLLDACDGGLEPTTAKSFLYQILRGISYC 116 Query: 596 HSAGILHRDLKPGNLLVN 649 H ILHRDLKP NLL+N Sbjct: 117 HDHRILHRDLKPQNLLIN 134
>BUR1_YARLI (Q6C842) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 706 Score = 67.0 bits (162), Expect = 5e-11 Identities = 47/144 (32%), Positives = 68/144 (47%), Gaps = 4/144 (2%) Frame = +2 Query: 230 IDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXX 409 + Y P+ IG G +G V + T VA+KKI + Sbjct: 34 VTESYKPLGKIGEGTFGEVFRAEQITTKRHVALKKILLHSEKEGFPVTALREIRILKLLR 93 Query: 410 XXNVIALKDIMMPIHRRSFKD---VYLVSELMDTDLHQIV-KSSQPLSNDHCQYFLFQLL 577 NVI L D+ + +S K+ VY+V+ MD DL ++ S LS H + ++ QLL Sbjct: 94 HENVIPLVDLAVERGDQSKKERGCVYMVTPYMDHDLAGLLGNQSVQLSPAHIKCYMLQLL 153 Query: 578 RGLKYLHSAGILHRDLKPGNLLVN 649 G+ YLH+ LHRD+K N+LVN Sbjct: 154 EGIGYLHAKKFLHRDIKAANILVN 177
>ICK_HUMAN (Q9UPZ9) Serine/threonine-protein kinase ICK (EC 2.7.11.22)| (Intestinal cell kinase) (hICK) (MAK-related kinase) (MRK) (Laryngeal cancer kinase 2) (LCK2) Length = 632 Score = 67.0 bits (162), Expect = 5e-11 Identities = 41/136 (30%), Positives = 68/136 (50%), Gaps = 1/136 (0%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 +Y I+ +G G YG V + E+ E +AIKK+ F + + N Sbjct: 3 RYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHA-N 61 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHC-QYFLFQLLRGLKYL 595 V+ LK+++ R +Y + E M +L+Q++K L + + ++Q+L+GL ++ Sbjct: 62 VVKLKEVI-----RENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFI 116 Query: 596 HSAGILHRDLKPGNLL 643 H G HRDLKP NLL Sbjct: 117 HKHGFFHRDLKPENLL 132
>AL2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.11.22)| (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein) Length = 384 Score = 67.0 bits (162), Expect = 5e-11 Identities = 48/144 (33%), Positives = 73/144 (50%), Gaps = 2/144 (1%) Frame = +2 Query: 224 FEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXX 403 F + Y+ ++ +G G+Y V I++ + VA+K I+ + V Sbjct: 46 FGAASSYLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEGVP-FTAIREASLLKG 104 Query: 404 XXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQP--LSNDHCQYFLFQLL 577 N++ L DI IH + + + V E M TDL Q + S P L + + F+FQLL Sbjct: 105 LKHANIVLLHDI---IHTK--ETLTFVFEYMHTDLAQYM-SQHPGGLHPHNVRLFMFQLL 158 Query: 578 RGLKYLHSAGILHRDLKPGNLLVN 649 RGL Y+H +LHRDLKP NLL++ Sbjct: 159 RGLAYIHHQHVLHRDLKPQNLLIS 182
>CDC21_PEA (P19026) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (p34) (Fragment) Length = 148 Score = 66.6 bits (161), Expect = 6e-11 Identities = 44/130 (33%), Positives = 67/130 (51%), Gaps = 4/130 (3%) Frame = +2 Query: 281 IVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNVIALKDIMMPIHRR 460 +V + ++ TNE +A+KKI ++ N++ L+D++ Sbjct: 1 VVYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHRNIVRLQDVV-----H 55 Query: 461 SFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQY--FLFQLLRGLKYLHSAGILHRDLKPG 634 S K +YLV E +D DL + + SS D Q FL+Q+L G+ Y HS +LHRDLKP Sbjct: 56 SEKRLYLVFEYLDLDLKKHMDSSPEFVKDPRQVKMFLYQMLCGIAYCHSHRVLHRDLKPQ 115 Query: 635 NLLVN--ANC 658 NLL++ NC Sbjct: 116 NLLIDRRTNC 125
>CDK7_MOUSE (Q03147) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (Protein-tyrosine kinase MPK-7) (CR4 protein kinas Length = 346 Score = 66.6 bits (161), Expect = 6e-11 Identities = 48/145 (33%), Positives = 74/145 (51%), Gaps = 6/145 (4%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXX- 415 +Y + +G G + V + ++ TN+ VAIKKI +R +A Sbjct: 11 RYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIK--LGHRSEAKDGINRTALREIKLLQE 68 Query: 416 ----NVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVK-SSQPLSNDHCQYFLFQLLR 580 N+I L D H+ ++ LV + M+TDL I+K +S L+ H + ++ L+ Sbjct: 69 LSHPNIIGLLDAFG--HK---SNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQ 123 Query: 581 GLKYLHSAGILHRDLKPGNLLVNAN 655 GL+YLH ILHRDLKP NLL++ N Sbjct: 124 GLEYLHQHWILHRDLKPNNLLLDEN 148
>CDK7_HUMAN (P50613) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (STK1) (CAK1) Length = 346 Score = 66.6 bits (161), Expect = 6e-11 Identities = 48/145 (33%), Positives = 74/145 (51%), Gaps = 6/145 (4%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXX- 415 +Y + +G G + V + ++ TN+ VAIKKI +R +A Sbjct: 11 RYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIK--LGHRSEAKDGINRTALREIKLLQE 68 Query: 416 ----NVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVK-SSQPLSNDHCQYFLFQLLR 580 N+I L D H+ ++ LV + M+TDL I+K +S L+ H + ++ L+ Sbjct: 69 LSHPNIIGLLDAFG--HK---SNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQ 123 Query: 581 GLKYLHSAGILHRDLKPGNLLVNAN 655 GL+YLH ILHRDLKP NLL++ N Sbjct: 124 GLEYLHQHWILHRDLKPNNLLLDEN 148
>MAK_RAT (P20793) Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male| germ cell-associated kinase) Length = 622 Score = 66.2 bits (160), Expect = 8e-11 Identities = 41/136 (30%), Positives = 68/136 (50%), Gaps = 1/136 (0%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 +Y ++ +G G YG V + E+ E VAIK++ F + D N Sbjct: 3 RYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSW-DECMNLREVKSLKKLNHAN 61 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHC-QYFLFQLLRGLKYL 595 VI LK+++ R +Y + E M +L+Q++K L + + ++Q+L+GL ++ Sbjct: 62 VIKLKEVI-----RENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFI 116 Query: 596 HSAGILHRDLKPGNLL 643 H G HRD+KP NLL Sbjct: 117 HKHGFFHRDMKPENLL 132
>GSK3H_DICDI (P51136) Glycogen synthase kinase-3 homolog (EC 2.7.11.26) (GSK-3)| Length = 467 Score = 66.2 bits (160), Expect = 8e-11 Identities = 43/144 (29%), Positives = 73/144 (50%), Gaps = 6/144 (4%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 Y+ IG G++G+V +I +T E VAIKK+ D N+ Sbjct: 56 YITEGVIGNGSFGVVTQAIVADTKEVVAIKKVLQ------DQRYKNRELQIMKMLNHINI 109 Query: 422 IALKDIMMPIHRRSFKDVYL--VSELMDTDLHQIVK----SSQPLSNDHCQYFLFQLLRG 583 ++LK+ + +VYL V E + ++++ + S QP+ N + +++QL R Sbjct: 110 VSLKN---SFYTSDNDEVYLNLVLEYVPDTVYRVSRHYSMSKQPVPNIFVKLYIYQLCRS 166 Query: 584 LKYLHSAGILHRDLKPGNLLVNAN 655 + Y+HS GI HRD+KP NLL++ + Sbjct: 167 INYIHSLGICHRDIKPQNLLLDTS 190
>PFTK1_HUMAN (O94921) Serine/threonine-protein kinase PFTAIRE-1 (EC 2.7.11.22)| Length = 469 Score = 66.2 bits (160), Expect = 8e-11 Identities = 47/137 (34%), Positives = 69/137 (50%), Gaps = 1/137 (0%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 Y ++ +G G+Y V ++ + VA+K I + + N+ Sbjct: 135 YEKLEKLGEGSYATVYKGKSKVNGKLVALKVIR-LQEEEGTPFTAIREASLLKGLKHANI 193 Query: 422 IALKDIMMPIHRRSFKDVYLVSELMDTDLHQIV-KSSQPLSNDHCQYFLFQLLRGLKYLH 598 + L DI IH + + + LV E + TDL Q + K L D+ + FLFQLLRGL Y+H Sbjct: 194 VLLHDI---IHTK--ETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIH 248 Query: 599 SAGILHRDLKPGNLLVN 649 ILHRDLKP NLL++ Sbjct: 249 QRYILHRDLKPQNLLIS 265
>CDK3_MOUSE (Q80YP0) Truncated cell division protein kinase 3 homolog| Length = 186 Score = 66.2 bits (160), Expect = 8e-11 Identities = 44/135 (32%), Positives = 68/135 (50%), Gaps = 2/135 (1%) Frame = +2 Query: 251 IKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNVIAL 430 ++ IG G YG+V + N+ T + VA+KKI + N+I L Sbjct: 7 VEKIGEGTYGVVYKARNKVTGQLVALKKIRLDLEAEGVPSTAVREISLLKELKHPNIIKL 66 Query: 431 KDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSS--QPLSNDHCQYFLFQLLRGLKYLHSA 604 D+ +HR K +Y+V E + DL + + SS L + +L QLL G+ + HS Sbjct: 67 LDV---VHRE--KKLYMVFEFLTQDLKRHMDSSPTSELPLPVVKSYLAQLLEGVSFCHSH 121 Query: 605 GILHRDLKPGNLLVN 649 ++HRDLKP NLL++ Sbjct: 122 RVIHRDLKPQNLLLD 136
>MAK_HUMAN (P20794) Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male| germ cell-associated kinase) Length = 623 Score = 66.2 bits (160), Expect = 8e-11 Identities = 41/136 (30%), Positives = 68/136 (50%), Gaps = 1/136 (0%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 +Y ++ +G G YG V + E+ E VAIK++ F + D N Sbjct: 3 RYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSW-DECMNLREVKSLKKLNHAN 61 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHC-QYFLFQLLRGLKYL 595 VI LK+++ R +Y + E M +L+Q++K L + + ++Q+L+GL ++ Sbjct: 62 VIKLKEVI-----RENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFI 116 Query: 596 HSAGILHRDLKPGNLL 643 H G HRD+KP NLL Sbjct: 117 HKHGFFHRDMKPENLL 132
>CDC2H_PLAFK (Q07785) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (PfPK5) Length = 288 Score = 65.9 bits (159), Expect = 1e-10 Identities = 46/138 (33%), Positives = 68/138 (49%), Gaps = 1/138 (0%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 KY ++ IG G YG+V + N E A+KKI ++ N Sbjct: 3 KYHGLEKIGEGTYGVVYKAQNNY-GETFALKKIRLEKEDEGIPSTTIREISILKELKHSN 61 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQP-LSNDHCQYFLFQLLRGLKYL 595 ++ L D+ IH + K + LV E +D DL +++ + L + + FL QLL G+ Y Sbjct: 62 IVKLYDV---IHTK--KRLVLVFEHLDQDLKKLLDVCEGGLESVTAKSFLLQLLNGIAYC 116 Query: 596 HSAGILHRDLKPGNLLVN 649 H +LHRDLKP NLL+N Sbjct: 117 HDRRVLHRDLKPQNLLIN 134
>CDC2H_PLAF7 (P61075) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 65.9 bits (159), Expect = 1e-10 Identities = 46/138 (33%), Positives = 68/138 (49%), Gaps = 1/138 (0%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 KY ++ IG G YG+V + N E A+KKI ++ N Sbjct: 3 KYHGLEKIGEGTYGVVYKAQNNY-GETFALKKIRLEKEDEGIPSTTIREISILKELKHSN 61 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQP-LSNDHCQYFLFQLLRGLKYL 595 ++ L D+ IH + K + LV E +D DL +++ + L + + FL QLL G+ Y Sbjct: 62 IVKLYDV---IHTK--KRLVLVFEHLDQDLKKLLDVCEGGLESVTAKSFLLQLLNGIAYC 116 Query: 596 HSAGILHRDLKPGNLLVN 649 H +LHRDLKP NLL+N Sbjct: 117 HDRRVLHRDLKPQNLLIN 134
>PCTK3_HUMAN (Q07002) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 472 Score = 65.9 bits (159), Expect = 1e-10 Identities = 44/137 (32%), Positives = 65/137 (47%), Gaps = 1/137 (0%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 YV + +G G Y V ++ VA+K+I + N+ Sbjct: 142 YVKLDKLGEGTYATVFKGRSKLMENLVALKEIRLEHEEGAPCTAIREVSLLKNLKHA-NI 200 Query: 422 IALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDH-CQYFLFQLLRGLKYLH 598 + L D++ + + + LV E +D+DL Q + L + H + F+FQLLRGL Y H Sbjct: 201 VTLHDLI-----HTDRSLTLVFEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCH 255 Query: 599 SAGILHRDLKPGNLLVN 649 ILHRDLKP NLL+N Sbjct: 256 HRKILHRDLKPQNLLIN 272
>CDK10_HUMAN (Q15131) Cell division protein kinase 10 (EC 2.7.11.22)| (Serine/threonine-protein kinase PISSLRE) Length = 360 Score = 65.5 bits (158), Expect = 1e-10 Identities = 41/137 (29%), Positives = 70/137 (51%), Gaps = 1/137 (0%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 ++ + IG G YGIV + + +T+E VA+KK+ + N Sbjct: 38 EFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRHPN 97 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQ-PLSNDHCQYFLFQLLRGLKYL 595 ++ LK++++ H S ++LV + DL ++++ P S + + Q+LRGL+YL Sbjct: 98 IVELKEVVVGNHLES---IFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQYL 154 Query: 596 HSAGILHRDLKPGNLLV 646 H I+HRDLK NLL+ Sbjct: 155 HRNFIIHRDLKVSNLLM 171
>CHK2_MOUSE (Q9Z265) Serine/threonine-protein kinase Chk2 (EC 2.7.11.1)| Length = 546 Score = 65.5 bits (158), Expect = 1e-10 Identities = 45/149 (30%), Positives = 76/149 (51%), Gaps = 7/149 (4%) Frame = +2 Query: 227 EIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINN---VFDNRVDAXXXXXXXXXX 397 E+ +Y+ K +G GA G V + ++T +KVAIK I+ + +A Sbjct: 219 ELRDEYIMSKTLGSGACGEVKMAFERKTCQKVAIKIISKRRFALGSSREADTAPSVETEI 278 Query: 398 XXXXXXN---VIALKDIMMPIHRRSFKDVYLVSELMDT-DLHQIVKSSQPLSNDHCQYFL 565 N +I +KD+ +D Y+V ELM+ +L V ++ L C+ + Sbjct: 279 EILKKLNHPCIIKIKDVF------DAEDYYIVLELMEGGELFDRVVGNKRLKEATCKLYF 332 Query: 566 FQLLRGLKYLHSAGILHRDLKPGNLLVNA 652 +Q+L ++YLH GI+HRDLKP N+L+++ Sbjct: 333 YQMLVAVQYLHENGIIHRDLKPENVLLSS 361
>CDK7_RAT (P51952) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 protein kinase) (P39 Mo15) (Fragment) Length = 329 Score = 65.5 bits (158), Expect = 1e-10 Identities = 47/138 (34%), Positives = 71/138 (51%), Gaps = 6/138 (4%) Frame = +2 Query: 260 IGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXX-----NVI 424 +G G + V + ++ TN+ VAIKKI +R +A N+I Sbjct: 10 LGEGQFATVYKARDKNTNQIVAIKKIK--LGHRSEAKDGINRTALREIKLLQELSHPNII 67 Query: 425 ALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVK-SSQPLSNDHCQYFLFQLLRGLKYLHS 601 L D H+ ++ LV + M+TDL I+K +S L+ H + ++ L+GL+YLH Sbjct: 68 GLLDAFG--HK---SNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQ 122 Query: 602 AGILHRDLKPGNLLVNAN 655 ILHRDLKP NLL++ N Sbjct: 123 HWILHRDLKPNNLLLDEN 140
>PFTK1_MOUSE (O35495) Serine/threonine-protein kinase PFTAIRE-1 (EC 2.7.11.22)| Length = 469 Score = 65.5 bits (158), Expect = 1e-10 Identities = 46/137 (33%), Positives = 69/137 (50%), Gaps = 1/137 (0%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 Y ++ +G G+Y V ++ + VA+K I + + N+ Sbjct: 135 YEKLEKLGEGSYATVYKGKSKVNGKLVALKVIR-LQEEEGTPFTAIREASLLKGLKHANI 193 Query: 422 IALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQP-LSNDHCQYFLFQLLRGLKYLH 598 + L DI IH + + + LV E + TDL Q ++ L D+ + FLFQLLRGL Y+H Sbjct: 194 VLLHDI---IHTK--ETLTLVFEYVHTDLCQYMEQHPGGLHPDNVKLFLFQLLRGLSYIH 248 Query: 599 SAGILHRDLKPGNLLVN 649 ILHRDLKP NLL++ Sbjct: 249 QRYILHRDLKPQNLLIS 265
>CDKL5_HUMAN (O76039) Cyclin-dependent kinase-like 5 (EC 2.7.11.22)| (Serine/threonine-protein kinase 9) Length = 1030 Score = 64.7 bits (156), Expect = 2e-10 Identities = 39/140 (27%), Positives = 74/140 (52%), Gaps = 1/140 (0%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 K+ + +G GAYG+V ++ET+E VAIKK + +N N Sbjct: 12 KFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQEN 71 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSS-QPLSNDHCQYFLFQLLRGLKYL 595 ++ LK+ RR K +YLV E ++ ++ ++++ + + + +++QL++ + + Sbjct: 72 IVELKEAF----RRRGK-LYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWC 126 Query: 596 HSAGILHRDLKPGNLLVNAN 655 H I+HRD+KP NLL++ N Sbjct: 127 HKNDIVHRDIKPENLLISHN 146
>CCRK_PONPY (Q5R7I7) Cell cycle-related kinase (EC 2.7.11.22)| Length = 346 Score = 64.7 bits (156), Expect = 2e-10 Identities = 45/141 (31%), Positives = 73/141 (51%), Gaps = 2/141 (1%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKIN-NVFDNRVDAXXXXXXXXXXXXXXXX 415 +Y + IG GA+GIV + + ET E VA+KK+ ++ + Sbjct: 3 QYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQALREIKALQEMEDNQ 62 Query: 416 NVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQ-PLSNDHCQYFLFQLLRGLKY 592 V+ LK + H F L E M +DL ++V+ +Q PL+ + +L LL+G+ + Sbjct: 63 YVVQLKAVFP--HSAGF---VLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVSF 117 Query: 593 LHSAGILHRDLKPGNLLVNAN 655 H+ I+HRDLKP NLL++A+ Sbjct: 118 CHANNIVHRDLKPANLLISAS 138
>CDC2H_PLAVI (Q9XZD6) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (Pvcrk2) Length = 288 Score = 64.3 bits (155), Expect = 3e-10 Identities = 46/138 (33%), Positives = 67/138 (48%), Gaps = 1/138 (0%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 KY ++ IG G YG+V + N E A+KKI ++ N Sbjct: 3 KYHGLEKIGEGTYGVVYKAQNNY-GETFALKKIRLEKEDEGIPSTAIREISILKELKHSN 61 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQP-LSNDHCQYFLFQLLRGLKYL 595 ++ L D+ IH + K + LV E +D DL +++ L + + FL QLL G+ Y Sbjct: 62 IVKLYDV---IHTK--KRLILVFEHLDQDLKKLLDVCDGGLESVTAKSFLLQLLSGIAYC 116 Query: 596 HSAGILHRDLKPGNLLVN 649 H +LHRDLKP NLL+N Sbjct: 117 HEHRVLHRDLKPQNLLIN 134
>CDC2H_PLAKH (O96821) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 64.3 bits (155), Expect = 3e-10 Identities = 46/138 (33%), Positives = 67/138 (48%), Gaps = 1/138 (0%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 KY ++ IG G YG+V + N E A+KKI ++ N Sbjct: 3 KYHGLEKIGEGTYGVVYKAQNNY-GETFALKKIRLEKEDEGIPSTAIREISILKELKHSN 61 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQP-LSNDHCQYFLFQLLRGLKYL 595 ++ L D+ IH + K + LV E +D DL +++ L + + FL QLL G+ Y Sbjct: 62 IVKLYDV---IHTK--KRLILVFEHLDQDLKKLLDVCDGGLESVTAKSFLLQLLSGIAYC 116 Query: 596 HSAGILHRDLKPGNLLVN 649 H +LHRDLKP NLL+N Sbjct: 117 HEHRVLHRDLKPQNLLIN 134
>KSG6_ARATH (Q39010) Shaggy-related protein kinase dzeta (EC 2.7.11.1)| (ASK-dzeta) Length = 412 Score = 64.3 bits (155), Expect = 3e-10 Identities = 44/141 (31%), Positives = 71/141 (50%), Gaps = 5/141 (3%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 Y+ + +G G++GIV + ET E VAIKK+ D NV Sbjct: 72 YMAERVVGTGSFGIVFQAKCLETGESVAIKKVLQ------DRRYKNRELQLMRLMDHPNV 125 Query: 422 IALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVK----SSQPLSNDHCQYFLFQLLRGLK 589 ++LK R + LV E + L++++K S+Q + + + + +Q+ RGL Sbjct: 126 VSLKHCFFSTTTRDELFLNLVMEYVPETLYRVLKHYTSSNQRMPIFYVKLYTYQIFRGLA 185 Query: 590 YLHSA-GILHRDLKPGNLLVN 649 Y+H+A G+ HRD+KP NLLV+ Sbjct: 186 YIHTAPGVCHRDIKPQNLLVD 206
>CD2L7_HUMAN (Q9NYV4) Cell division cycle 2-related protein kinase 7 (EC| 2.7.11.22) (CDC2-related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS) Length = 1490 Score = 64.3 bits (155), Expect = 3e-10 Identities = 44/143 (30%), Positives = 69/143 (48%), Gaps = 6/143 (4%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 K+ I IG G YG V + +++T E VA+KK+ + + Sbjct: 726 KFDIIGIIGEGTYGQVYKARDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIHRS 785 Query: 419 VIALKDIMMPIH-----RRSFKDVYLVSELMDTDLHQIVKSSQP-LSNDHCQYFLFQLLR 580 V+ +K+I+ ++ YLV E MD DL +++S S DH + F+ QL+ Sbjct: 786 VVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQLME 845 Query: 581 GLKYLHSAGILHRDLKPGNLLVN 649 GL+Y H LHRD+K N+L+N Sbjct: 846 GLEYCHKKNFLHRDIKCSNILLN 868
>CDC2_CAEEL (P34556) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 332 Score = 64.3 bits (155), Expect = 3e-10 Identities = 42/162 (25%), Positives = 75/162 (46%), Gaps = 3/162 (1%) Frame = +2 Query: 179 IGNHGKHYYTMWQTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNR 358 + + G YT+ + ++ IG G YG+V N+ TN VA+KKI ++ Sbjct: 9 VAHEGDSVYTL--------NDFTKLEKIGEGTYGVVYKGKNRRTNAMVAMKKIRLESEDE 60 Query: 359 VDAXXXXXXXXXXXXXXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKS---S 529 NV+ L+ ++M +R ++L+ E + DL + + Sbjct: 61 GVPSTAVREISLLKELQHPNVVGLEAVIMQENR-----LFLIFEFLSFDLKRYMDQLGKD 115 Query: 530 QPLSNDHCQYFLFQLLRGLKYLHSAGILHRDLKPGNLLVNAN 655 + L + + + FQ+L+ + + H ++HRDLKP NLLV+ N Sbjct: 116 EYLPLETLKSYTFQILQAMCFCHQRRVIHRDLKPQNLLVDNN 157
>CDK7_DICDI (P54685) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (MO15 homolog) Length = 362 Score = 64.3 bits (155), Expect = 3e-10 Identities = 47/137 (34%), Positives = 69/137 (50%), Gaps = 5/137 (3%) Frame = +2 Query: 260 IGRGAYGIVCSSINQETNEKVAIKKINNVF-DNRVDAXXXXXXXXXXXXXXXX---NVIA 427 IG G YG+V + + T + VAIKKI + N+ D NV+ Sbjct: 10 IGEGTYGVVSRATVKATGQIVAIKKIRKILIQNQTDDGINFSAIREIKILQELKHDNVVN 69 Query: 428 LKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKS-SQPLSNDHCQYFLFQLLRGLKYLHSA 604 L DI H+ +VYLV ELM DL ++++ S L + ++ LL+G++ H Sbjct: 70 LLDIFA--HK---SNVYLVFELMQWDLQEVIEDKSIILKPADIKSYMKMLLQGIEACHRN 124 Query: 605 GILHRDLKPGNLLVNAN 655 +LHRDLKP NLL++ N Sbjct: 125 WVLHRDLKPNNLLMSIN 141
>DUN1_YEAST (P39009) DNA damage response protein kinase DUN1 (EC 2.7.11.1)| Length = 513 Score = 63.9 bits (154), Expect = 4e-10 Identities = 40/139 (28%), Positives = 69/139 (49%), Gaps = 2/139 (1%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKIN-NVFDNRVDAXXXXXXXXXXXXXXXX 415 KY+ K +G G Y +V + N++T ++VA+K + D++ Sbjct: 199 KYLLGKELGAGHYALVKEAKNKKTGQQVAVKIFHAQQNDDQKKNKQFREETNILMRVQHP 258 Query: 416 NVIALKDIMM-PIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLRGLKY 592 N++ L D + PI + + ++ ++ D +L + + L D + QLL GLKY Sbjct: 259 NIVNLLDSFVEPISKSQIQKYLVLEKIDDGELFERIVRKTCLRQDESKALFKQLLTGLKY 318 Query: 593 LHSAGILHRDLKPGNLLVN 649 LH I+HRD+KP N+L+N Sbjct: 319 LHEQNIIHRDIKPENILLN 337
>CSK2A_CAEEL (P18334) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II alpha| subunit) Length = 360 Score = 63.9 bits (154), Expect = 4e-10 Identities = 40/138 (28%), Positives = 69/138 (50%), Gaps = 1/138 (0%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 Y ++ +GRG Y V T+EKV +K + V ++ N+ Sbjct: 38 YQLVRKLGRGKYSEVFEGFKMSTDEKVVVKILKPVKKKKIKREIKILENLRGGT----NI 93 Query: 422 IALKDIMM-PIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLRGLKYLH 598 I L D++ PI R + + ++D Q+ Q LS+ +Y+L++LL+ L + H Sbjct: 94 ITLLDVVKDPISRTP---ALIFEHVNNSDFKQLY---QTLSDYDIRYYLYELLKALDFCH 147 Query: 599 SAGILHRDLKPGNLLVNA 652 S GI+HRD+KP N++++A Sbjct: 148 SQGIMHRDVKPHNVMIDA 165
>CSK2A_DROME (P08181) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II alpha| subunit) Length = 335 Score = 63.9 bits (154), Expect = 4e-10 Identities = 39/136 (28%), Positives = 66/136 (48%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 Y ++ +GRG Y V +IN T EK +K + V ++ + Sbjct: 36 YQLVRKLGRGKYSEVFEAINITTTEKCVVKILKPVKKKKIKREIKILENLRGGTNIITLL 95 Query: 422 IALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLRGLKYLHS 601 +KD P+ R + + +TD Q+ Q L++ +Y+LF+LL+ L Y HS Sbjct: 96 AVVKD---PVSRTP---ALIFEHVNNTDFKQLY---QTLTDYEIRYYLFELLKALDYCHS 146 Query: 602 AGILHRDLKPGNLLVN 649 GI+HRD+KP N++++ Sbjct: 147 MGIMHRDVKPHNVMID 162
>CSK2A_SPOFR (O76484) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II alpha| subunit) Length = 353 Score = 63.9 bits (154), Expect = 4e-10 Identities = 40/137 (29%), Positives = 69/137 (50%), Gaps = 1/137 (0%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 Y ++ +GRG Y V +IN NEK +K + V ++ N+ Sbjct: 39 YQLVRKLGRGKYSEVFEAINITNNEKCVVKILKPVKKKKIKREIKILENLRGGT----NI 94 Query: 422 IALKDIMM-PIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLRGLKYLH 598 I L+ ++ P+ R + + +TD Q+ Q LS+ +Y+L++LL+ L Y H Sbjct: 95 ITLQAVVKDPVSRTP---ALIFEHVNNTDFKQLY---QTLSDYDIRYYLYELLKALDYCH 148 Query: 599 SAGILHRDLKPGNLLVN 649 S GI+HRD+KP N++++ Sbjct: 149 SMGIMHRDVKPHNVMID 165
>KC47_ORYSA (P29620) CDC2+/CDC28-related protein kinase R2 (EC 2.7.11.22)| Length = 424 Score = 63.5 bits (153), Expect = 5e-10 Identities = 41/141 (29%), Positives = 69/141 (48%), Gaps = 2/141 (1%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 +Y+ + +G G YG+V +++ +T VAIKKI N Sbjct: 18 RYLKREVLGEGTYGVVFKAVDTKTGNTVAIKKIRLGKYKEGVNFTALREIKLLKELKDSN 77 Query: 419 VIALKDIMMPIHRRSFK-DVYLVSELMDTDLHQIVKSSQ-PLSNDHCQYFLFQLLRGLKY 592 +I L D +K +++LV E M+TDL +++ LS + ++ +L+GL + Sbjct: 78 IIELIDAF------PYKGNLHLVFEFMETDLEAVIRDRNIVLSPADTKSYIQMMLKGLAF 131 Query: 593 LHSAGILHRDLKPGNLLVNAN 655 H +LHRD+KP NLL+ A+ Sbjct: 132 CHKKWVLHRDMKPNNLLIGAD 152
>KSG7_ARATH (Q39011) Shaggy-related protein kinase eta (EC 2.7.11.1) (ASK-eta)| (BRASSINOSTEROID-INSENSITIVE 2) (ULTRACURVATA1) Length = 380 Score = 63.5 bits (153), Expect = 5e-10 Identities = 43/141 (30%), Positives = 71/141 (50%), Gaps = 5/141 (3%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 Y+ + +G G++GIV + ET E VAIKK+ D NV Sbjct: 40 YMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQ------DRRYKNRELQLMRVMDHPNV 93 Query: 422 IALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVK----SSQPLSNDHCQYFLFQLLRGLK 589 + LK + + LV E + L++++K ++Q + + + +++Q+ RGL Sbjct: 94 VCLKHCFFSTTSKDELFLNLVMEYVPESLYRVLKHYSSANQRMPLVYVKLYMYQIFRGLA 153 Query: 590 YLHS-AGILHRDLKPGNLLVN 649 Y+H+ AG+ HRDLKP NLLV+ Sbjct: 154 YIHNVAGVCHRDLKPQNLLVD 174
>CDKL2_MACFA (Q4R7T5) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| Length = 570 Score = 63.5 bits (153), Expect = 5e-10 Identities = 42/138 (30%), Positives = 67/138 (48%), Gaps = 1/138 (0%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 KY + +G G+YG+V N++T VAIKK D+++ N Sbjct: 3 KYENLGLVGEGSYGMVVKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHEN 62 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMD-TDLHQIVKSSQPLSNDHCQYFLFQLLRGLKYL 595 ++ L ++ + K YLV E +D T L + L Q +LFQ++ G+ + Sbjct: 63 LVNLLEVC-----KKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFC 117 Query: 596 HSAGILHRDLKPGNLLVN 649 HS I+HRD+KP N+LV+ Sbjct: 118 HSHNIIHRDIKPENILVS 135
>CDKL2_PONPY (Q5R754) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| Length = 493 Score = 63.5 bits (153), Expect = 5e-10 Identities = 42/138 (30%), Positives = 67/138 (48%), Gaps = 1/138 (0%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 KY + +G G+YG+V N++T VAIKK D+++ N Sbjct: 3 KYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHEN 62 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMD-TDLHQIVKSSQPLSNDHCQYFLFQLLRGLKYL 595 ++ L ++ + K YLV E +D T L + L Q +LFQ++ G+ + Sbjct: 63 LVNLLEVC-----KKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFC 117 Query: 596 HSAGILHRDLKPGNLLVN 649 HS I+HRD+KP N+LV+ Sbjct: 118 HSHNIIHRDIKPENILVS 135
>CDKL2_HUMAN (Q92772) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIAMRE) (Protein kinase p56 KKIAMRE) Length = 493 Score = 63.5 bits (153), Expect = 5e-10 Identities = 42/138 (30%), Positives = 67/138 (48%), Gaps = 1/138 (0%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 KY + +G G+YG+V N++T VAIKK D+++ N Sbjct: 3 KYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHEN 62 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMD-TDLHQIVKSSQPLSNDHCQYFLFQLLRGLKYL 595 ++ L ++ + K YLV E +D T L + L Q +LFQ++ G+ + Sbjct: 63 LVNLLEVC-----KKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFC 117 Query: 596 HSAGILHRDLKPGNLLVN 649 HS I+HRD+KP N+LV+ Sbjct: 118 HSHNIIHRDIKPENILVS 135
>CDK7_XENLA (P20911) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (40 kDa protein kinase) (P40 MO15) (CDC2/CDK2,4-activating kinase) Length = 352 Score = 63.5 bits (153), Expect = 5e-10 Identities = 47/145 (32%), Positives = 73/145 (50%), Gaps = 6/145 (4%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXX- 415 +Y + +G G + V + ++ T+ VAIKKI +R +A Sbjct: 17 QYEKLDFLGEGQFATVYKARDKNTDRIVAIKKIK--LGHRAEANDGINRTALREIKLLQE 74 Query: 416 ----NVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVK-SSQPLSNDHCQYFLFQLLR 580 N+I L D H+ ++ LV + M+TDL I+K +S L+ H + ++ L+ Sbjct: 75 LSHPNIIGLLDAFG--HK---SNISLVFDFMETDLEVIIKDTSLVLTPAHIKSYMLMTLQ 129 Query: 581 GLKYLHSAGILHRDLKPGNLLVNAN 655 GL+YLH ILHRDLKP NLL++ N Sbjct: 130 GLEYLHHLWILHRDLKPNNLLLDEN 154
>CCRK_RAT (Q4KM34) Cell cycle-related kinase (EC 2.7.11.22)| Length = 346 Score = 63.5 bits (153), Expect = 5e-10 Identities = 45/141 (31%), Positives = 73/141 (51%), Gaps = 2/141 (1%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKIN-NVFDNRVDAXXXXXXXXXXXXXXXX 415 +Y + IG GA+GIV + + ET E VA+KK+ ++ + Sbjct: 3 QYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQALREIKALQEIEDSQ 62 Query: 416 NVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQ-PLSNDHCQYFLFQLLRGLKY 592 V+ LK + H F L E M +DL ++V+ +Q PL+ + +L LL+G+ + Sbjct: 63 YVVQLKAVFP--HGAGF---VLAFEFMLSDLAEVVRHAQRPLAPAQVKSYLQMLLKGVAF 117 Query: 593 LHSAGILHRDLKPGNLLVNAN 655 H+ I+HRDLKP NLL++A+ Sbjct: 118 CHANNIVHRDLKPANLLISAS 138
>CCRK_MOUSE (Q9JHU3) Cell cycle-related kinase (EC 2.7.11.22)| (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) (CDK-related protein kinase PNQLARE) Length = 346 Score = 63.5 bits (153), Expect = 5e-10 Identities = 45/141 (31%), Positives = 73/141 (51%), Gaps = 2/141 (1%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKIN-NVFDNRVDAXXXXXXXXXXXXXXXX 415 +Y + IG GA+GIV + + ET E VA+KK+ ++ + Sbjct: 3 QYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQALREIKALQEIEDSQ 62 Query: 416 NVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQ-PLSNDHCQYFLFQLLRGLKY 592 V+ LK + H F L E M +DL ++V+ +Q PL+ + +L LL+G+ + Sbjct: 63 YVVQLKAVFP--HGAGF---VLAFEFMLSDLAEVVRHAQRPLAPAQVKSYLQMLLKGVAF 117 Query: 593 LHSAGILHRDLKPGNLLVNAN 655 H+ I+HRDLKP NLL++A+ Sbjct: 118 CHANNIVHRDLKPANLLISAS 138
>PHO85_KLULA (Q92241) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 304 Score = 63.5 bits (153), Expect = 5e-10 Identities = 43/144 (29%), Positives = 69/144 (47%), Gaps = 6/144 (4%) Frame = +2 Query: 236 TKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXX 415 +++ ++ +G G Y V +N+ T VA+K++ + Sbjct: 5 SQFKQLEKVGNGTYATVYKGLNKTTGVYVALKEVK-LDSEEGTPSTAIREISLMKELKHD 63 Query: 416 NVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIV------KSSQPLSNDHCQYFLFQLL 577 N++ L D+ IH + + LV E MD DL + + S + L D +YF +QLL Sbjct: 64 NIVRLFDV---IHTEN--KLTLVFEFMDNDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLL 118 Query: 578 RGLKYLHSAGILHRDLKPGNLLVN 649 +G+ + H ILHRDLKP NLL+N Sbjct: 119 QGVAFCHENRILHRDLKPQNLLIN 142
>CSK21_RAT (P19139) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II)| Length = 391 Score = 63.2 bits (152), Expect = 7e-10 Identities = 39/137 (28%), Positives = 70/137 (51%), Gaps = 1/137 (0%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 Y ++ +GRG Y V +IN NEKV +K + V ++ N+ Sbjct: 39 YQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGP----NI 94 Query: 422 IALKDIMM-PIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLRGLKYLH 598 I L DI+ P+ R + + +TD Q+ Q L++ +++++++L+ L Y H Sbjct: 95 ITLADIVKDPVSRTP---ALVFEHVNNTDFKQLY---QTLTDYDIRFYMYEILKALDYCH 148 Query: 599 SAGILHRDLKPGNLLVN 649 S GI+HRD+KP N++++ Sbjct: 149 SMGIMHRDVKPHNVMID 165
>CSK21_MOUSE (Q60737) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II)| Length = 391 Score = 63.2 bits (152), Expect = 7e-10 Identities = 39/137 (28%), Positives = 70/137 (51%), Gaps = 1/137 (0%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 Y ++ +GRG Y V +IN NEKV +K + V ++ N+ Sbjct: 39 YQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGP----NI 94 Query: 422 IALKDIMM-PIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLRGLKYLH 598 I L DI+ P+ R + + +TD Q+ Q L++ +++++++L+ L Y H Sbjct: 95 ITLADIVKDPVSRTP---ALVFEHVNNTDFKQLY---QTLTDYDIRFYMYEILKALDYCH 148 Query: 599 SAGILHRDLKPGNLLVN 649 S GI+HRD+KP N++++ Sbjct: 149 SMGIMHRDVKPHNVMID 165
>CSK21_HUMAN (P68400) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II)| Length = 391 Score = 63.2 bits (152), Expect = 7e-10 Identities = 39/137 (28%), Positives = 70/137 (51%), Gaps = 1/137 (0%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 Y ++ +GRG Y V +IN NEKV +K + V ++ N+ Sbjct: 39 YQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGP----NI 94 Query: 422 IALKDIMM-PIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLRGLKYLH 598 I L DI+ P+ R + + +TD Q+ Q L++ +++++++L+ L Y H Sbjct: 95 ITLADIVKDPVSRTP---ALVFEHVNNTDFKQLY---QTLTDYDIRFYMYEILKALDYCH 148 Query: 599 SAGILHRDLKPGNLLVN 649 S GI+HRD+KP N++++ Sbjct: 149 SMGIMHRDVKPHNVMID 165
>CSK21_CHICK (P21868) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II)| Length = 391 Score = 63.2 bits (152), Expect = 7e-10 Identities = 39/137 (28%), Positives = 70/137 (51%), Gaps = 1/137 (0%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 Y ++ +GRG Y V +IN NEKV +K + V ++ N+ Sbjct: 39 YQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGP----NI 94 Query: 422 IALKDIMM-PIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLRGLKYLH 598 I L DI+ P+ R + + +TD Q+ Q L++ +++++++L+ L Y H Sbjct: 95 ITLADIVKDPVSRTP---ALVFEHVNNTDFKQLY---QTLTDYDIRFYMYEILKALDYCH 148 Query: 599 SAGILHRDLKPGNLLVN 649 S GI+HRD+KP N++++ Sbjct: 149 SMGIMHRDVKPHNVMID 165
>CSK21_BOVIN (P68399) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II)| Length = 391 Score = 63.2 bits (152), Expect = 7e-10 Identities = 39/137 (28%), Positives = 70/137 (51%), Gaps = 1/137 (0%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 Y ++ +GRG Y V +IN NEKV +K + V ++ N+ Sbjct: 39 YQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGP----NI 94 Query: 422 IALKDIMM-PIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLRGLKYLH 598 I L DI+ P+ R + + +TD Q+ Q L++ +++++++L+ L Y H Sbjct: 95 ITLADIVKDPVSRTP---ALVFEHVNNTDFKQLY---QTLTDYDIRFYMYEILKALDYCH 148 Query: 599 SAGILHRDLKPGNLLVN 649 S GI+HRD+KP N++++ Sbjct: 149 SMGIMHRDVKPHNVMID 165
>CSK22_XENLA (P28020) Casein kinase II subunit alpha' (EC 2.7.11.1) (CK II)| Length = 392 Score = 63.2 bits (152), Expect = 7e-10 Identities = 39/137 (28%), Positives = 70/137 (51%), Gaps = 1/137 (0%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 Y ++ +GRG Y V +IN NEKV +K + V ++ N+ Sbjct: 39 YQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGP----NI 94 Query: 422 IALKDIMM-PIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLRGLKYLH 598 I L DI+ P+ R + + +TD Q+ Q L++ +++++++L+ L Y H Sbjct: 95 ITLADIVKDPVSRTP---ALVFEHVNNTDFKQLY---QTLTDYDIRFYMYEILKALDYCH 148 Query: 599 SAGILHRDLKPGNLLVN 649 S GI+HRD+KP N++++ Sbjct: 149 SMGIMHRDVKPHNVMID 165
>CDKL2_RABIT (Q9TTK0) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIAMRE) Length = 566 Score = 63.2 bits (152), Expect = 7e-10 Identities = 41/138 (29%), Positives = 68/138 (49%), Gaps = 1/138 (0%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 KY + +G G+YG+V N+++ VAIKK D+++ N Sbjct: 3 KYENLGLVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHEN 62 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMD-TDLHQIVKSSQPLSNDHCQYFLFQLLRGLKYL 595 ++ L ++ + K YLV E +D T L + L + Q +LFQ++ G+ + Sbjct: 63 LVNLLEVC-----KKKKRWYLVFEFVDHTILDDLELFPNGLDDQVVQKYLFQIINGIGFC 117 Query: 596 HSAGILHRDLKPGNLLVN 649 HS I+HRD+KP N+LV+ Sbjct: 118 HSHNIIHRDIKPENILVS 135
>GSK3H_DROME (P83101) Putative glycogen synthase kinase-3 homolog (EC 2.7.11.26)| (GSK-3) (Protein gasket) Length = 501 Score = 62.8 bits (151), Expect = 9e-10 Identities = 44/148 (29%), Positives = 73/148 (49%), Gaps = 8/148 (5%) Frame = +2 Query: 233 DTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKI--NNVFDNRVDAXXXXXXXXXXXXX 406 + Y K +G G++G+V + +NE VAIKK+ + F NR Sbjct: 30 EISYTDAKVVGNGSFGVVFQAKMVPSNEMVAIKKVLQDRRFKNR--------ELQIMRKL 81 Query: 407 XXXNVIALKDIMMPIHRRSFKDVYL--VSELMDTDLHQI----VKSSQPLSNDHCQYFLF 568 N+I LK + +VYL V E + L+++ ++ Q L + + +++ Sbjct: 82 RHDNIITLKWFFFSSGEKR-DEVYLNLVMEFLPETLYKVERQYARAKQTLPVNFVRLYMY 140 Query: 569 QLLRGLKYLHSAGILHRDLKPGNLLVNA 652 QLLR + YLHS G HRD+KP N+L+++ Sbjct: 141 QLLRSMGYLHSLGFCHRDIKPQNMLLDS 168
>BUR1_NEUCR (Q871M9) Serine/threonine-protein kinase bur-1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 545 Score = 62.8 bits (151), Expect = 9e-10 Identities = 46/143 (32%), Positives = 72/143 (50%), Gaps = 7/143 (4%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAX--XXXXXXXXXXXXXXX 415 Y + +G G +G V + +++T VA+KKI + N D Sbjct: 26 YEVLGKLGEGTFGEVHRARSRKTGALVALKKI--IMHNERDGFPITALREIKLLKLLSHK 83 Query: 416 NVIALKDIMMPIHRRSFKD----VYLVSELMDTDLHQIVKS-SQPLSNDHCQYFLFQLLR 580 NV+ L+++ + R+ K VY+V+ MD DL ++ + S + + +L QLL Sbjct: 84 NVLRLEEMAIEHPPRTDKRTRPIVYMVTPYMDHDLSGLLDNPSVRFTEPQVKCYLLQLLE 143 Query: 581 GLKYLHSAGILHRDLKPGNLLVN 649 GLKYLH+ ILHRD+K NLL+N Sbjct: 144 GLKYLHANHILHRDMKAANLLIN 166
>CCRK_MACMU (Q5EDC3) Cell cycle-related kinase (EC 2.7.11.22)| (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) Length = 243 Score = 62.4 bits (150), Expect = 1e-09 Identities = 46/145 (31%), Positives = 75/145 (51%), Gaps = 6/145 (4%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNE-----KVAIKKINNVFDNRVDAXXXXXXXXXXXX 403 +Y + IG GA+GIV + + ET E KVA++++ + F N+ Sbjct: 3 QYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQA----LREIKALQEM 58 Query: 404 XXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQ-PLSNDHCQYFLFQLLR 580 V+ LK + H F L E M +DL ++V+ +Q PL+ + +L LL+ Sbjct: 59 GDNQYVVQLKAVFP--HGGGF---VLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLK 113 Query: 581 GLKYLHSAGILHRDLKPGNLLVNAN 655 G+ + H+ I+HRDLKP NLL++A+ Sbjct: 114 GVAFCHANNIVHRDLKPANLLISAS 138
>CCRK_HUMAN (Q8IZL9) Cell cycle-related kinase (EC 2.7.11.22)| (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) Length = 346 Score = 62.4 bits (150), Expect = 1e-09 Identities = 46/145 (31%), Positives = 75/145 (51%), Gaps = 6/145 (4%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNE-----KVAIKKINNVFDNRVDAXXXXXXXXXXXX 403 +Y + IG GA+GIV + + ET E KVA++++ + F N+ Sbjct: 3 QYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQA----LREIKALQEM 58 Query: 404 XXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQ-PLSNDHCQYFLFQLLR 580 V+ LK + H F L E M +DL ++V+ +Q PL+ + +L LL+ Sbjct: 59 EDNQYVVQLKAVFP--HGGGF---VLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLK 113 Query: 581 GLKYLHSAGILHRDLKPGNLLVNAN 655 G+ + H+ I+HRDLKP NLL++A+ Sbjct: 114 GVAFCHANNIVHRDLKPANLLISAS 138
>CDKL2_RAT (Q5XIT0) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| Length = 507 Score = 62.0 bits (149), Expect = 2e-09 Identities = 41/138 (29%), Positives = 67/138 (48%), Gaps = 1/138 (0%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 KY + +G G+YG+V N+++ VAIKK D+++ N Sbjct: 3 KYENLGLVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHEN 62 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMD-TDLHQIVKSSQPLSNDHCQYFLFQLLRGLKYL 595 ++ L ++ + K YLV E +D T L + L Q +LFQ++ G+ + Sbjct: 63 LVNLLEVC-----KKKKRWYLVFEFVDHTILDDLKLFPNGLDYQVVQKYLFQIINGIGFC 117 Query: 596 HSAGILHRDLKPGNLLVN 649 HS I+HRD+KP N+LV+ Sbjct: 118 HSHNIIHRDIKPENILVS 135
>CSK21_RABIT (P33674) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II)| Length = 391 Score = 62.0 bits (149), Expect = 2e-09 Identities = 38/136 (27%), Positives = 68/136 (50%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 Y ++ +GRG Y V +IN NEKV +K + V ++ N+ Sbjct: 39 YQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGP----NI 94 Query: 422 IALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLRGLKYLHS 601 I L DI+ R+ + +TD Q+ Q L++ +++++++L+ L Y HS Sbjct: 95 ITLADIVKDPASRT--PALAFEHVNNTDFKQLY---QTLTDYDIRFYMYEILKALDYCHS 149 Query: 602 AGILHRDLKPGNLLVN 649 GI+HRD+KP N++++ Sbjct: 150 MGIMHRDVKPHNVMID 165
>KIN28_YEAST (P06242) Serine/threonine-protein kinase KIN28 (EC 2.7.11.23)| Length = 306 Score = 62.0 bits (149), Expect = 2e-09 Identities = 44/141 (31%), Positives = 67/141 (47%), Gaps = 2/141 (1%) Frame = +2 Query: 227 EIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKIN-NVFDNRVDAXXXXXXXXXXXX 403 +++ +Y K +G G Y +V T K+AIK+I + F + +D Sbjct: 2 KVNMEYTKEKKVGEGTYAVVYLGCQHSTGRKIAIKEIKTSEFKDGLDMSAIREVKYLQEM 61 Query: 404 XXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSND-HCQYFLFQLLR 580 NVI L DI M ++ ++ LV E + TDL ++K L + ++ LR Sbjct: 62 QHP-NVIELIDIFM-----AYDNLNLVLEFLPTDLEVVIKDKSILFTPADIKAWMLMTLR 115 Query: 581 GLKYLHSAGILHRDLKPGNLL 643 G+ + H ILHRDLKP NLL Sbjct: 116 GVYHCHRNFILHRDLKPNNLL 136
>CDKL2_MOUSE (Q9QUK0) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIAMRE) Length = 568 Score = 62.0 bits (149), Expect = 2e-09 Identities = 41/138 (29%), Positives = 67/138 (48%), Gaps = 1/138 (0%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 KY + +G G+YG+V N+++ VAIKK D+++ N Sbjct: 3 KYENLGLVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHEN 62 Query: 419 VIALKDIMMPIHRRSFKDVYLVSELMD-TDLHQIVKSSQPLSNDHCQYFLFQLLRGLKYL 595 ++ L ++ + K YLV E +D T L + L Q +LFQ++ G+ + Sbjct: 63 LVNLLEVC-----KKKKRWYLVFEFVDHTILDDLKLFPNGLDYQVVQKYLFQIINGIGFC 117 Query: 596 HSAGILHRDLKPGNLLVN 649 HS I+HRD+KP N+LV+ Sbjct: 118 HSHNIIHRDIKPENILVS 135
>CD2L1_HUMAN (P21127) PITSLRE serine/threonine-protein kinase CDC2L1 (EC| 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1) Length = 795 Score = 61.6 bits (148), Expect = 2e-09 Identities = 36/131 (27%), Positives = 68/131 (51%), Gaps = 1/131 (0%) Frame = +2 Query: 260 IGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNVIALKDI 439 I G YG+V + +++T+E VA+K++ + N++ +++I Sbjct: 444 IEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREI 503 Query: 440 MMPIHRRSFKDVYLVSELMDTDLHQIVKS-SQPLSNDHCQYFLFQLLRGLKYLHSAGILH 616 ++ + +Y+V ++ DL ++++ QP + + QLLRG+K+LH ILH Sbjct: 504 VVG---SNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILH 560 Query: 617 RDLKPGNLLVN 649 RDLK NLL++ Sbjct: 561 RDLKTSNLLLS 571
>CD2L5_MOUSE (Q69ZA1) Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22)| (CDC2-related protein kinase 5) Length = 1511 Score = 61.6 bits (148), Expect = 2e-09 Identities = 43/143 (30%), Positives = 68/143 (47%), Gaps = 6/143 (4%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 K+ I IG G YG V + +++T E VA+KK+ + + Sbjct: 704 KFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQS 763 Query: 419 VIALKDIMMPIH-----RRSFKDVYLVSELMDTDLHQIVKSSQPLSND-HCQYFLFQLLR 580 +I +K+I+ ++ YLV E MD DL +++S N+ H + F+ QL+ Sbjct: 764 IINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLME 823 Query: 581 GLKYLHSAGILHRDLKPGNLLVN 649 GL Y H LHRD+K N+L+N Sbjct: 824 GLDYCHKKNFLHRDIKCSNILLN 846
>CD2L5_HUMAN (Q14004) Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22)| (CDC2-related protein kinase 5) (Cholinesterase-related cell division controller) Length = 1512 Score = 61.6 bits (148), Expect = 2e-09 Identities = 43/143 (30%), Positives = 68/143 (47%), Gaps = 6/143 (4%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 K+ I IG G YG V + +++T E VA+KK+ + + Sbjct: 704 KFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQS 763 Query: 419 VIALKDIMMPIH-----RRSFKDVYLVSELMDTDLHQIVKSSQPLSND-HCQYFLFQLLR 580 +I +K+I+ ++ YLV E MD DL +++S N+ H + F+ QL+ Sbjct: 764 IINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLME 823 Query: 581 GLKYLHSAGILHRDLKPGNLLVN 649 GL Y H LHRD+K N+L+N Sbjct: 824 GLDYCHKKNFLHRDIKCSNILLN 846
>CD2L2_HUMAN (Q9UQ88) PITSLRE serine/threonine-protein kinase CDC2L2 (EC| 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11) Length = 780 Score = 61.6 bits (148), Expect = 2e-09 Identities = 36/131 (27%), Positives = 68/131 (51%), Gaps = 1/131 (0%) Frame = +2 Query: 260 IGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNVIALKDI 439 I G YG+V + +++T+E VA+K++ + N++ +++I Sbjct: 429 IEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREI 488 Query: 440 MMPIHRRSFKDVYLVSELMDTDLHQIVKS-SQPLSNDHCQYFLFQLLRGLKYLHSAGILH 616 ++ + +Y+V ++ DL ++++ QP + + QLLRG+K+LH ILH Sbjct: 489 VVG---SNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILH 545 Query: 617 RDLKPGNLLVN 649 RDLK NLL++ Sbjct: 546 RDLKTSNLLLS 556
>CRK1_LEIME (Q06309) Cell division protein kinase 2 homolog CRK1 (EC 2.7.11.23)| Length = 301 Score = 61.6 bits (148), Expect = 2e-09 Identities = 40/139 (28%), Positives = 66/139 (47%), Gaps = 1/139 (0%) Frame = +2 Query: 236 TKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXX 415 ++Y + IG G YG+V + + T VA+K+I + Sbjct: 3 SRYERQEKIGEGTYGVVYKARDTSTAATVALKRIRLDSEEEGVPCTAIREISLLKELRHE 62 Query: 416 NVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIV-KSSQPLSNDHCQYFLFQLLRGLKY 592 N++ L D+ HR + +V E +D DL + + + + L Q+F+ LLRG+ + Sbjct: 63 NIVKLLDVCHSEHRLT-----IVFEYLDLDLKKYLDRENGNLDAATIQHFMRDLLRGVAF 117 Query: 593 LHSAGILHRDLKPGNLLVN 649 H +LHRDLKP NLL++ Sbjct: 118 CHQRSVLHRDLKPQNLLIS 136
>PHO85_YEAST (P17157) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 305 Score = 61.6 bits (148), Expect = 2e-09 Identities = 43/144 (29%), Positives = 69/144 (47%), Gaps = 6/144 (4%) Frame = +2 Query: 236 TKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXX 415 +++ ++ +G G Y V +N+ T VA+K++ + Sbjct: 5 SQFKQLEKLGNGTYATVYKGLNKTTGVYVALKEVK-LDSEEGTPSTAIREISLMKELKHE 63 Query: 416 NVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSS------QPLSNDHCQYFLFQLL 577 N++ L D+ IH + + LV E MD DL + + S + L + +YF +QLL Sbjct: 64 NIVRLYDV---IHTEN--KLTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLL 118 Query: 578 RGLKYLHSAGILHRDLKPGNLLVN 649 +GL + H ILHRDLKP NLL+N Sbjct: 119 QGLAFCHENKILHRDLKPQNLLIN 142
>MSK1_MEDSA (P51137) Glycogen synthase kinase-3 homolog MsK-1 (EC 2.7.11.1)| Length = 411 Score = 61.2 bits (147), Expect = 3e-09 Identities = 40/141 (28%), Positives = 67/141 (47%), Gaps = 5/141 (3%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 Y+ + +G G++G+V + ET E VAIKK+ D NV Sbjct: 75 YMAERVVGHGSFGVVFQAKCLETGETVAIKKVLQ------DKRYKNRELQTMRLLDHPNV 128 Query: 422 IALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKS----SQPLSNDHCQYFLFQLLRGLK 589 ++LK + + LV E + +H+++K +Q + + + + +Q+ R L Sbjct: 129 VSLKHCFFSTTEKDELYLNLVLEYVPETVHRVIKHYSKLNQRMPMIYVKLYTYQIFRALS 188 Query: 590 YLHSA-GILHRDLKPGNLLVN 649 Y+H G+ HRD+KP NLLVN Sbjct: 189 YIHRCIGVCHRDIKPQNLLVN 209
>KSG9_ARATH (Q39012) Shaggy-related protein kinase iota (EC 2.7.11.1)| (ASK-iota) Length = 407 Score = 61.2 bits (147), Expect = 3e-09 Identities = 43/141 (30%), Positives = 70/141 (49%), Gaps = 5/141 (3%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 Y+ + +G G++GIV + ET E VAIKK+ D NV Sbjct: 70 YMAERVVGTGSFGIVFQAKCLETGESVAIKKVLQ------DRRYKNRELQLMRPMDHPNV 123 Query: 422 IALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVK----SSQPLSNDHCQYFLFQLLRGLK 589 I+LK R + LV E + L+++++ S+Q + + + + +Q+ RGL Sbjct: 124 ISLKHCFFSTTSRDELFLNLVMEYVPETLYRVLRHYTSSNQRMPIFYVKLYTYQIFRGLA 183 Query: 590 YLHSA-GILHRDLKPGNLLVN 649 Y+H+ G+ HRD+KP NLLV+ Sbjct: 184 YIHTVPGVCHRDVKPQNLLVD 204
>KSG3_ARATH (P43289) Shaggy-related protein kinase gamma (EC 2.7.11.1)| (ASK-gamma) Length = 409 Score = 61.2 bits (147), Expect = 3e-09 Identities = 40/141 (28%), Positives = 66/141 (46%), Gaps = 5/141 (3%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 Y+ + +G G++G+V + ET E VAIKK+ D NV Sbjct: 73 YMAERVVGHGSFGVVFQAKCLETGETVAIKKVLQ------DRRYKNRELQTMRLLDHPNV 126 Query: 422 IALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSND----HCQYFLFQLLRGLK 589 ++LK + + LV E + +H+++K L+ + + + +Q+ R L Sbjct: 127 VSLKHCFFSTTEKDELYLNLVLEYVPETVHRVIKHYNKLNQRMPLVYVKLYTYQIFRSLS 186 Query: 590 YLHSA-GILHRDLKPGNLLVN 649 Y+H G+ HRD+KP NLLVN Sbjct: 187 YIHRCIGVCHRDIKPQNLLVN 207
>KSG1_ARATH (P43288) Shaggy-related protein kinase alpha (EC 2.7.11.1)| (ASK-alpha) Length = 405 Score = 61.2 bits (147), Expect = 3e-09 Identities = 40/141 (28%), Positives = 66/141 (46%), Gaps = 5/141 (3%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 Y+ + +G G++G+V + ET E VAIKK+ D NV Sbjct: 69 YMAERVVGHGSFGVVFQAKCLETGETVAIKKVLQ------DRRYKNRELQTMRLLDHPNV 122 Query: 422 IALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSND----HCQYFLFQLLRGLK 589 ++LK + + LV E + +H+++K L+ + + + +Q+ R L Sbjct: 123 VSLKHCFFSTTEKDELYLNLVLEYVPETVHRVIKHYNKLNQRMPLIYVKLYTYQIFRALS 182 Query: 590 YLHSA-GILHRDLKPGNLLVN 649 Y+H G+ HRD+KP NLLVN Sbjct: 183 YIHRCIGVCHRDIKPQNLLVN 203
>PHO85_DEBHA (Q6BRY2) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 330 Score = 60.8 bits (146), Expect = 3e-09 Identities = 41/141 (29%), Positives = 68/141 (48%), Gaps = 3/141 (2%) Frame = +2 Query: 236 TKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXX 415 +++ ++ +G G Y V N+ + VA+K+IN + Sbjct: 6 SQFQQLEKLGEGTYATVYKGRNRTNGQLVALKEIN-LDSEEGTPSTAIREISLMKELDHE 64 Query: 416 NVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKS---SQPLSNDHCQYFLFQLLRGL 586 N++ L D+ IH + + LV E MD DL + +++ L + F+FQLL+G+ Sbjct: 65 NIVTLYDV---IHTEN--KLTLVFEFMDKDLKKYMEAHGNQGALDLKIVKSFIFQLLKGI 119 Query: 587 KYLHSAGILHRDLKPGNLLVN 649 + H +LHRDLKP NLL+N Sbjct: 120 MFCHDNRVLHRDLKPQNLLIN 140
>MSK2_MEDSA (P51138) Glycogen synthase kinase-3 homolog MsK-2 (EC 2.7.11.1)| Length = 411 Score = 60.8 bits (146), Expect = 3e-09 Identities = 40/141 (28%), Positives = 68/141 (48%), Gaps = 5/141 (3%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 Y+ + +G+G++G+V + ET E VAIKK+ D NV Sbjct: 74 YMAERAVGQGSFGVVFQAKCLETGETVAIKKVLQ------DKRYKNRELQTMRLLDHPNV 127 Query: 422 IALKDIMMPIHRRSFKDVYLVSELMDTDLHQIV----KSSQPLSNDHCQYFLFQLLRGLK 589 + LK + + LV E + +H+++ K +Q + + + + +Q+ R L Sbjct: 128 VTLKHCFFSTTEKDELYLNLVLEFVPETVHRVIRHYSKMNQRMPLIYVKLYSYQICRSLA 187 Query: 590 YLHS-AGILHRDLKPGNLLVN 649 Y+H+ G+ HRD+KP NLLVN Sbjct: 188 YIHNCVGVSHRDIKPQNLLVN 208
>CHK2_HUMAN (O96017) Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (Cds1)| Length = 543 Score = 60.8 bits (146), Expect = 3e-09 Identities = 44/144 (30%), Positives = 74/144 (51%), Gaps = 6/144 (4%) Frame = +2 Query: 239 KYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXN 418 +Y+ K +G GA G V + ++T +KVAIK I+ + Sbjct: 219 EYIMSKTLGSGACGEVKLAFERKTCKKVAIKIIS-----KRKFAIGSAREADPALNVETE 273 Query: 419 VIALKDIMMP--IHRRSF---KDVYLVSELMDT-DLHQIVKSSQPLSNDHCQYFLFQLLR 580 + LK + P I ++F +D Y+V ELM+ +L V ++ L C+ + +Q+L Sbjct: 274 IEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLL 333 Query: 581 GLKYLHSAGILHRDLKPGNLLVNA 652 ++YLH GI+HRDLKP N+L+++ Sbjct: 334 AVQYLHENGIIHRDLKPENVLLSS 357
>CSK2A_MAIZE (P28523) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II)| (CK2-alpha) Length = 332 Score = 60.5 bits (145), Expect = 4e-09 Identities = 37/136 (27%), Positives = 68/136 (50%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 Y ++ +GRG Y V IN NEK IK + V ++ N+ Sbjct: 34 YEVVRKVGRGKYSEVFEGINVNNNEKCIIKILKPVKKKKIKREIKILQNLCGGP----NI 89 Query: 422 IALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLRGLKYLHS 601 + L DI+ H ++ ++ + +TD + + L++ +Y++++LL+ L Y HS Sbjct: 90 VKLLDIVRDQHSKTPSLIF--EYVNNTDFKVLYPT---LTDYDIRYYIYELLKALDYCHS 144 Query: 602 AGILHRDLKPGNLLVN 649 GI+HRD+KP N++++ Sbjct: 145 QGIMHRDVKPHNVMID 160
>MSK1_TOBAC (Q40518) Shaggy-related protein kinase NtK-1 (EC 2.7.11.1)| Length = 409 Score = 60.5 bits (145), Expect = 4e-09 Identities = 44/161 (27%), Positives = 72/161 (44%), Gaps = 5/161 (3%) Frame = +2 Query: 182 GNHGKHYYTMWQTMFEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRV 361 G HG+ T+ Y+ + +G+G++G+V + ET E VAIKK+ Sbjct: 62 GRHGQPKQTI---------SYMAERIVGQGSFGVVFQAKCLETGETVAIKKVLQ------ 106 Query: 362 DAXXXXXXXXXXXXXXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLS 541 D NV+ LK + + LV E + +H+++K L+ Sbjct: 107 DKRYKNRELQTMRLLDHPNVVCLKHCFFSTTEKDEVYLNLVLEYVPETVHRVIKHYNKLN 166 Query: 542 NDH----CQYFLFQLLRGLKYLH-SAGILHRDLKPGNLLVN 649 + + +Q+ R L Y+H + G+ HRD+KP NLLVN Sbjct: 167 QRMPLILVKLYTYQIFRALSYIHHTIGVCHRDIKPQNLLVN 207
>CDKL3_RAT (Q9JM01) Cyclin-dependent kinase-like 3 (EC 2.7.11.22)| (Serine/threonine protein kinase NKIATRE) Length = 593 Score = 60.1 bits (144), Expect = 6e-09 Identities = 40/137 (29%), Positives = 68/137 (49%), Gaps = 1/137 (0%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 Y + +G G+YG V +++T VAIK + V+ N+ Sbjct: 4 YETLGKVGEGSYGTVMKCKHKDTGRIVAIKIFYEKPEKSVNKIATREIKFLKQFRHE-NL 62 Query: 422 IALKDIMMPIHRRSFKDVYLVSELMD-TDLHQIVKSSQPLSNDHCQYFLFQLLRGLKYLH 598 + L ++ R K ++LV E +D T L ++ L + + +LFQ+LR ++YLH Sbjct: 63 VNLIEVF-----RQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIEYLH 117 Query: 599 SAGILHRDLKPGNLLVN 649 + I+HRD+KP N+LV+ Sbjct: 118 NNNIIHRDIKPENILVS 134
>CSK2A_THEPA (P28547) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II)| Length = 348 Score = 60.1 bits (144), Expect = 6e-09 Identities = 38/142 (26%), Positives = 68/142 (47%) Frame = +2 Query: 224 FEIDTKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXX 403 + + Y ++ IGRG + V IN T +K IK + V ++ Sbjct: 49 WNVPDSYEIVRKIGRGKFSEVFEGINTVTKDKCVIKILKPVKKKKIKREIKILQNLRGGP 108 Query: 404 XXXXNVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQPLSNDHCQYFLFQLLRG 583 N+I L DI+ R+ ++ + +TD + + LS +Y+++QLL+ Sbjct: 109 ----NIIKLLDIVKDPQSRTPSLIF--EHVNNTDFKTLYPT---LSIQDIKYYIYQLLKA 159 Query: 584 LKYLHSAGILHRDLKPGNLLVN 649 + Y HS GI+HRD+KP N++++ Sbjct: 160 MNYCHSQGIMHRDIKPHNVMID 181
>CDKL3_MOUSE (Q8BLF2) Cyclin-dependent kinase-like 3 (EC 2.7.11.22)| Length = 595 Score = 60.1 bits (144), Expect = 6e-09 Identities = 40/137 (29%), Positives = 68/137 (49%), Gaps = 1/137 (0%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 Y + +G G+YG V +++T VAIK + V+ N+ Sbjct: 4 YETLGKVGEGSYGTVMKCKHKDTGRIVAIKIFYEKPEKSVNKIATREIKFLKQFRHE-NL 62 Query: 422 IALKDIMMPIHRRSFKDVYLVSELMD-TDLHQIVKSSQPLSNDHCQYFLFQLLRGLKYLH 598 + L ++ R K ++LV E +D T L ++ L + + +LFQ+LR ++YLH Sbjct: 63 VNLIEVF-----RQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIEYLH 117 Query: 599 SAGILHRDLKPGNLLVN 649 + I+HRD+KP N+LV+ Sbjct: 118 NNNIIHRDIKPENILVS 134
>MOK_MOUSE (Q9WVS4) MAPK/MAK/MRK overlapping kinase (EC 2.7.11.22) (MOK| protein kinase) Length = 420 Score = 59.7 bits (143), Expect = 8e-09 Identities = 35/136 (25%), Positives = 64/136 (47%), Gaps = 1/136 (0%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 Y I IG G + V + A K++ F++ N+ Sbjct: 4 YKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQHFESIEQVNSLREIQALRRLNPHPNI 63 Query: 422 IALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVKSSQ-PLSNDHCQYFLFQLLRGLKYLH 598 +AL +++ R + L+ ELMD +++++++ + PLS +++QL + L ++H Sbjct: 64 LALHEVVFD---RKSGSLALICELMDMNIYELIRGRRHPLSEKKIMLYMYQLCKSLDHMH 120 Query: 599 SAGILHRDLKPGNLLV 646 GI HRD+KP N+LV Sbjct: 121 RNGIFHRDVKPENILV 136
>PHO85_CANAL (Q9HGY5) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) (CaPHO85) Length = 326 Score = 59.7 bits (143), Expect = 8e-09 Identities = 41/141 (29%), Positives = 67/141 (47%), Gaps = 3/141 (2%) Frame = +2 Query: 236 TKYVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXX 415 +++ ++ +G G Y V N+ T VA+K+I+ + Sbjct: 6 SQFQQLEKLGEGTYATVYKGRNRATGALVALKEIS-LDSEEGTPSTAIREISLMKELDHE 64 Query: 416 NVIALKDIMMPIHRRSFKDVYLVSELMDTDLHQIVK---SSQPLSNDHCQYFLFQLLRGL 586 N++ L D+ IH + + LV E MD DL + ++ L + F+FQLL+G+ Sbjct: 65 NIVTLYDV---IHTEN--KLTLVFEYMDKDLKKYMEVHGQQSALDLKVVKSFMFQLLKGI 119 Query: 587 KYLHSAGILHRDLKPGNLLVN 649 + H +LHRDLKP NLL+N Sbjct: 120 MFCHDNRVLHRDLKPQNLLIN 140
>CDKL3_MACFA (Q4R8T9) Cyclin-dependent kinase-like 3 (EC 2.7.11.22)| Length = 590 Score = 59.7 bits (143), Expect = 8e-09 Identities = 41/137 (29%), Positives = 67/137 (48%), Gaps = 1/137 (0%) Frame = +2 Query: 242 YVPIKPIGRGAYGIVCSSINQETNEKVAIKKINNVFDNRVDAXXXXXXXXXXXXXXXXNV 421 Y + +G G+YG V ++ T + VAIK + V+ N+ Sbjct: 4 YETLGKVGEGSYGTVMKCKHKNTGQIVAIKIFYERPEQSVNKIAMREIKFLKQFHHE-NL 62 Query: 422 IALKDIMMPIHRRSFKDVYLVSELMD-TDLHQIVKSSQPLSNDHCQYFLFQLLRGLKYLH 598 + L ++ R K ++LV E +D T L ++ L + + +LFQ+LR + YLH Sbjct: 63 VNLIEVF-----RQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIDYLH 117 Query: 599 SAGILHRDLKPGNLLVN 649 S I+HRD+KP N+LV+ Sbjct: 118 SNNIIHRDIKPENILVS 134 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 76,443,427 Number of Sequences: 219361 Number of extensions: 1423757 Number of successful extensions: 8446 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 7275 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 7846 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 6314008338 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
