ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | baal17c08 |
|---|---|
| Clone Library Name | barley_pub |
>CPK15_ARATH (P92937) CBL-interacting serine/threonine-protein kinase 15 (EC| 2.7.11.1) (Serine/threonine-protein kinase ATPK10) (SOS2-like protein kinase PKS3) (SOS-interacting protein 2) (SNF1-related kinase 3.1) Length = 421 Score = 183 bits (464), Expect = 2e-46 Identities = 88/143 (61%), Positives = 115/143 (80%) Frame = +2 Query: 53 LPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRL 232 L RYE K LG+G FAKVY ARH+ T + VAIKV+DKE+++K+G +QIKREI+ MR L Sbjct: 8 LMLRYEVGKFLGQGTFAKVYHARHLKTGDSVAIKVIDKERILKVGMTEQIKREISAMRLL 67 Query: 233 RHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCH 412 RHPNIV+LH+VMA KS+I+ VME+V+GG L+ + + G L+ED R+ FQQLV A+ FCH Sbjct: 68 RHPNIVELHEVMATKSKIYFVMEHVKGGELFNKV-STGKLREDVARKYFQQLVRAVDFCH 126 Query: 413 AQGVYHRDIKPDNLLVDEHGNLK 481 ++GV HRD+KP+NLL+DEHGNLK Sbjct: 127 SRGVCHRDLKPENLLLDEHGNLK 149
>CPK11_ARATH (O22932) CBL-interacting serine/threonine-protein kinase 11 (EC| 2.7.11.1) (SOS2-like protein kinase PKS5) (SOS-interacting protein 4) (SNF1-related kinase 3.22) Length = 435 Score = 170 bits (431), Expect = 2e-42 Identities = 87/159 (54%), Positives = 117/159 (73%), Gaps = 1/159 (0%) Frame = +2 Query: 8 PAQESGDGAMGDRPKLPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLG 187 P E G+ + L +YE KLLG G FAKV+ AR T + VA+K+++K+KL+ Sbjct: 2 PEIEIAAGSGDNNDALFGKYELGKLLGCGAFAKVFHARDRRTGQSVAVKILNKKKLLTNP 61 Query: 188 AV-QQIKREIAVMRRLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDE 364 A+ IKREI++MRRL HPNIV+LH+VMA KS+IF ME+V+GG L+ I +G L ED Sbjct: 62 ALANNIKREISIMRRLSHPNIVKLHEVMATKSKIFFAMEFVKGGELFNKISKHGRLSEDL 121 Query: 365 TRRIFQQLVSALTFCHAQGVYHRDIKPDNLLVDEHGNLK 481 +RR FQQL+SA+ +CHA+GVYHRD+KP+NLL+DE+GNLK Sbjct: 122 SRRYFQQLISAVGYCHARGVYHRDLKPENLLIDENGNLK 160
>CIPK1_ORYSA (Q6X4A2) CIPK-like protein 1 (EC 2.7.11.1) (OsCK1)| Length = 449 Score = 162 bits (409), Expect = 6e-40 Identities = 75/140 (53%), Positives = 107/140 (76%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHP 241 +YE + +GEG FAKV A++ + E VAIK++DKEK+ K V+QI+REI M+ ++HP Sbjct: 19 KYELGRTIGEGTFAKVRFAKNTENDEPVAIKILDKEKVQKHRLVEQIRREICTMKLVKHP 78 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 N+V+L +VM K+RIF+V+EYV GG L+ I NG LKE+E R+ FQQL++A+ +CH++G Sbjct: 79 NVVRLFEVMGSKARIFIVLEYVTGGELFEIIATNGRLKEEEARKYFQQLINAVDYCHSRG 138 Query: 422 VYHRDIKPDNLLVDEHGNLK 481 VYHRD+K +NLL+D GNLK Sbjct: 139 VYHRDLKLENLLLDASGNLK 158
>CPK24_ARATH (Q9LDI3) CBL-interacting serine/threonine-protein kinase 24 (EC| 2.7.11.1) (SNF1-related kinase 3.11) (SALT OVERLY SENSITIVE 2 protein) Length = 446 Score = 159 bits (402), Expect = 4e-39 Identities = 75/140 (53%), Positives = 106/140 (75%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHP 241 +YE + +GEG FAKV AR+ DT + VAIK+M K ++K V QIKREI++M+ +RHP Sbjct: 10 KYEVGRTIGEGTFAKVKFARNTDTGDNVAIKIMAKSTILKNRMVDQIKREISIMKIVRHP 69 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 NIV+L++V+A S+I++V+E+V GG L+ I G L+E E+R+ FQQLV A+ CH +G Sbjct: 70 NIVRLYEVLASPSKIYIVLEFVTGGELFDRIVHKGRLEESESRKYFQQLVDAVAHCHCKG 129 Query: 422 VYHRDIKPDNLLVDEHGNLK 481 VYHRD+KP+NLL+D +GNLK Sbjct: 130 VYHRDLKPENLLLDTNGNLK 149
>CIPK1_ARATH (Q8RWC9) CBL-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (SOS2-like protein kinase PKS13) (SNF1-related kinase 3.16) Length = 444 Score = 137 bits (345), Expect = 1e-32 Identities = 63/140 (45%), Positives = 100/140 (71%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHP 241 +YE + LGEGNF KV A+ + A+K++DK ++ L QIKREI ++ L+HP Sbjct: 19 KYELGRTLGEGNFGKVKFAKDTVSGHSFAVKIIDKSRIADLNFSLQIKREIRTLKMLKHP 78 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 +IV+LH+V+A K++I +VME V GG L+ I +NG L E + R++FQQL+ +++CH++G Sbjct: 79 HIVRLHEVLASKTKINMVMELVTGGELFDRIVSNGKLTETDGRKMFQQLIDGISYCHSKG 138 Query: 422 VYHRDIKPDNLLVDEHGNLK 481 V+HRD+K +N+L+D G++K Sbjct: 139 VFHRDLKLENVLLDAKGHIK 158
>SNF1_CANGA (Q00372) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 612 Score = 132 bits (332), Expect = 5e-31 Identities = 64/139 (46%), Positives = 97/139 (69%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 Y+ VK LGEG+F KV LA H+ T ++VA+K+++K+ L K +I+REI+ +R LRHP+ Sbjct: 39 YQIVKTLGEGSFGKVKLAYHVTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLRHPH 98 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 I++L+ V+ K I +V+EY G L+ +I + E E RR FQQ++SA+ +CH + Sbjct: 99 IIKLYDVIKSKDEIIMVIEYA-GNELFDYIVQRNKMSEQEARRFFQQIISAVEYCHRHKI 157 Query: 425 YHRDIKPDNLLVDEHGNLK 481 HRD+KP+NLL+DEH N+K Sbjct: 158 VHRDLKPENLLLDEHLNVK 176
>MARK2_HUMAN (Q7KZI7) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog) Length = 788 Score = 132 bits (331), Expect = 6e-31 Identities = 62/139 (44%), Positives = 101/139 (72%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 Y +K +G+GNFAKV LARH+ T +EVA+K++DK +L ++Q++ RE+ +M+ L HPN Sbjct: 53 YRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQL-NSSSLQKLFREVRIMKVLNHPN 111 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 IV+L +V+ + +++VMEY GG ++ ++ A+G +KE E R F+Q+VSA+ +CH + + Sbjct: 112 IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFI 171 Query: 425 YHRDIKPDNLLVDEHGNLK 481 HRD+K +NLL+D N+K Sbjct: 172 VHRDLKAENLLLDADMNIK 190
>MARK2_RAT (O08679) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1) Length = 722 Score = 132 bits (331), Expect = 6e-31 Identities = 62/139 (44%), Positives = 101/139 (72%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 Y +K +G+GNFAKV LARH+ T +EVA+K++DK +L ++Q++ RE+ +M+ L HPN Sbjct: 53 YRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQL-NSSSLQKLFREVRIMKVLNHPN 111 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 IV+L +V+ + +++VMEY GG ++ ++ A+G +KE E R F+Q+VSA+ +CH + + Sbjct: 112 IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFI 171 Query: 425 YHRDIKPDNLLVDEHGNLK 481 HRD+K +NLL+D N+K Sbjct: 172 VHRDLKAENLLLDADMNIK 190
>AAPK1_RAT (P54645) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 548 Score = 131 bits (329), Expect = 1e-30 Identities = 61/133 (45%), Positives = 95/133 (71%) Frame = +2 Query: 83 LGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPNIVQLHK 262 LG G F KV + +H T +VA+K+++++K+ L V +I+REI ++ RHP+I++L++ Sbjct: 22 LGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQ 81 Query: 263 VMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGVYHRDIK 442 V++ S IF+VMEYV GG L+ +I NG L E E+RR+FQQ++S + +CH V HRD+K Sbjct: 82 VISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLK 141 Query: 443 PDNLLVDEHGNLK 481 P+N+L+D H N K Sbjct: 142 PENVLLDAHMNAK 154
>AAPK1_MOUSE (Q5EG47) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 548 Score = 131 bits (329), Expect = 1e-30 Identities = 61/133 (45%), Positives = 95/133 (71%) Frame = +2 Query: 83 LGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPNIVQLHK 262 LG G F KV + +H T +VA+K+++++K+ L V +I+REI ++ RHP+I++L++ Sbjct: 22 LGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQ 81 Query: 263 VMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGVYHRDIK 442 V++ S IF+VMEYV GG L+ +I NG L E E+RR+FQQ++S + +CH V HRD+K Sbjct: 82 VISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLK 141 Query: 443 PDNLLVDEHGNLK 481 P+N+L+D H N K Sbjct: 142 PENVLLDAHMNAK 154
>SNF1_YEAST (P06782) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 633 Score = 131 bits (329), Expect = 1e-30 Identities = 64/139 (46%), Positives = 96/139 (69%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 Y+ VK LGEG+F KV LA H T ++VA+K+++K+ L K +I+REI+ +R LRHP+ Sbjct: 55 YQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLRHPH 114 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 I++L+ V+ K I +V+EY G L+ +I + E E RR FQQ++SA+ +CH + Sbjct: 115 IIKLYDVIKSKDEIIMVIEYA-GNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRHKI 173 Query: 425 YHRDIKPDNLLVDEHGNLK 481 HRD+KP+NLL+DEH N+K Sbjct: 174 VHRDLKPENLLLDEHLNVK 192
>AAPK1_PONPY (Q5RDH5) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 550 Score = 131 bits (329), Expect = 1e-30 Identities = 61/133 (45%), Positives = 95/133 (71%) Frame = +2 Query: 83 LGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPNIVQLHK 262 LG G F KV + +H T +VA+K+++++K+ L V +I+REI ++ RHP+I++L++ Sbjct: 24 LGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQ 83 Query: 263 VMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGVYHRDIK 442 V++ S IF+VMEYV GG L+ +I NG L E E+RR+FQQ++S + +CH V HRD+K Sbjct: 84 VISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLK 143 Query: 443 PDNLLVDEHGNLK 481 P+N+L+D H N K Sbjct: 144 PENVLLDAHMNAK 156
>AAPK1_HUMAN (Q13131) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 550 Score = 131 bits (329), Expect = 1e-30 Identities = 61/133 (45%), Positives = 95/133 (71%) Frame = +2 Query: 83 LGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPNIVQLHK 262 LG G F KV + +H T +VA+K+++++K+ L V +I+REI ++ RHP+I++L++ Sbjct: 24 LGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQ 83 Query: 263 VMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGVYHRDIK 442 V++ S IF+VMEYV GG L+ +I NG L E E+RR+FQQ++S + +CH V HRD+K Sbjct: 84 VISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLK 143 Query: 443 PDNLLVDEHGNLK 481 P+N+L+D H N K Sbjct: 144 PENVLLDAHMNAK 156
>MARK3_RAT (Q8VHF0) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| Length = 797 Score = 130 bits (328), Expect = 1e-30 Identities = 62/139 (44%), Positives = 100/139 (71%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 Y +K +G+GNFAKV LARH+ T EVAIK++DK +L ++Q++ RE+ +M+ L HPN Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPT-SLQKLFREVRIMKILNHPN 114 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 IV+L +V+ + ++++MEY GG ++ ++ A+G +KE E R F+Q+VSA+ +CH + + Sbjct: 115 IVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKRI 174 Query: 425 YHRDIKPDNLLVDEHGNLK 481 HRD+K +NLL+D N+K Sbjct: 175 VHRDLKAENLLLDADMNIK 193
>MARK3_MOUSE (Q03141) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| (MPK-10) (ELKL motif kinase 2) Length = 753 Score = 130 bits (328), Expect = 1e-30 Identities = 62/139 (44%), Positives = 100/139 (71%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 Y +K +G+GNFAKV LARH+ T EVAIK++DK +L ++Q++ RE+ +M+ L HPN Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPT-SLQKLFREVRIMKILNHPN 114 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 IV+L +V+ + ++++MEY GG ++ ++ A+G +KE E R F+Q+VSA+ +CH + + Sbjct: 115 IVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKRI 174 Query: 425 YHRDIKPDNLLVDEHGNLK 481 HRD+K +NLL+D N+K Sbjct: 175 VHRDLKAENLLLDADMNIK 193
>SNF1_CANTR (O94168) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 619 Score = 130 bits (327), Expect = 2e-30 Identities = 60/140 (42%), Positives = 100/140 (71%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHP 241 RY+ +K LGEG+F KV LA+H+ T ++VA+K+++++ L K +++REI+ +R LRHP Sbjct: 51 RYQIIKTLGEGSFGKVKLAQHVGTGQKVALKIINRKTLAKSDMQGRVEREISYLRLLRHP 110 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 +I++L+ V+ K I +V+E+ G L+ +I G + EDE RR FQQ+++A+ +CH Sbjct: 111 HIIKLYDVIKSKDEIIMVIEFA-GKELFDYIVQRGKMPEDEARRFFQQIIAAVEYCHRHK 169 Query: 422 VYHRDIKPDNLLVDEHGNLK 481 + HRD+KP+NLL+D+ N+K Sbjct: 170 IVHRDLKPENLLLDDQLNVK 189
>SNF1_CANAL (P52497) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 620 Score = 130 bits (326), Expect = 2e-30 Identities = 60/140 (42%), Positives = 100/140 (71%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHP 241 RY+ +K LGEG+F KV LA+H+ T ++VA+K+++++ L K +++REI+ +R LRHP Sbjct: 52 RYQILKTLGEGSFGKVKLAQHLGTGQKVALKIINRKTLAKSDMQGRVEREISYLRLLRHP 111 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 +I++L+ V+ K I +V+E+ G L+ +I G + EDE RR FQQ+++A+ +CH Sbjct: 112 HIIKLYDVIKSKDEIIMVIEFA-GKELFDYIVQRGKMPEDEARRFFQQIIAAVEYCHRHK 170 Query: 422 VYHRDIKPDNLLVDEHGNLK 481 + HRD+KP+NLL+D+ N+K Sbjct: 171 IVHRDLKPENLLLDDQLNVK 190
>SN1L2_CHICK (Q9IA88) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Qin-induced kinase) Length = 798 Score = 130 bits (326), Expect = 2e-30 Identities = 61/146 (41%), Positives = 100/146 (68%) Frame = +2 Query: 44 RPKLPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVM 223 RP Y+ + LG+GNFA V LARH TK +VAIK++DK +L +++I RE+ +M Sbjct: 19 RPLRVGFYDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDPSN-LEKIYREVQIM 77 Query: 224 RRLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALT 403 + L HP+I++L++VM K +++V E+ + G ++ H+ +NG L E E R+ F Q++SA+ Sbjct: 78 KLLNHPHIIKLYQVMETKDMLYIVTEFAKNGEMFDHLTSNGHLSESEARKKFWQILSAVE 137 Query: 404 FCHAQGVYHRDIKPDNLLVDEHGNLK 481 +CH+ + HRD+K +NLL+D + N+K Sbjct: 138 YCHSHHIVHRDLKTENLLLDANMNIK 163
>MARK1_RAT (O08678) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) Length = 793 Score = 129 bits (325), Expect = 3e-30 Identities = 64/150 (42%), Positives = 104/150 (69%) Frame = +2 Query: 32 AMGDRPKLPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKRE 211 A ++P + Y K +G+GNFAKV LARH+ T EVA+K++DK +L ++Q++ RE Sbjct: 50 ATDEQPHI-GNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPT-SLQKLFRE 107 Query: 212 IAVMRRLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLV 391 + +M+ L HPNIV+L +V+ + +++VMEY GG ++ ++ A+G +KE E R F+Q+V Sbjct: 108 VRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIV 167 Query: 392 SALTFCHAQGVYHRDIKPDNLLVDEHGNLK 481 SA+ +CH + + HRD+K +NLL+D N+K Sbjct: 168 SAVQYCHQKCIVHRDLKAENLLLDADMNIK 197
>MARK1_MOUSE (Q8VHJ5) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) (ELKL motif serine/threonine-protein kinase 3) Length = 795 Score = 129 bits (325), Expect = 3e-30 Identities = 64/150 (42%), Positives = 104/150 (69%) Frame = +2 Query: 32 AMGDRPKLPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKRE 211 A ++P + Y K +G+GNFAKV LARH+ T EVA+K++DK +L ++Q++ RE Sbjct: 50 ATDEQPHI-GNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPT-SLQKLFRE 107 Query: 212 IAVMRRLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLV 391 + +M+ L HPNIV+L +V+ + +++VMEY GG ++ ++ A+G +KE E R F+Q+V Sbjct: 108 VRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIV 167 Query: 392 SALTFCHAQGVYHRDIKPDNLLVDEHGNLK 481 SA+ +CH + + HRD+K +NLL+D N+K Sbjct: 168 SAVQYCHQKCIVHRDLKAENLLLDADMNIK 197
>MARK4_MOUSE (Q8CIP4) MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1)| Length = 752 Score = 129 bits (325), Expect = 3e-30 Identities = 60/139 (43%), Positives = 99/139 (71%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 Y ++ +G+GNFAKV LARH+ T EVAIK++DK +L ++Q++ RE+ +M+ L HPN Sbjct: 59 YRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQL-NPSSLQKLFREVRIMKGLNHPN 117 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 IV+L +V+ + +++VMEY G ++ ++ ++G +KE E R F+Q+VSA+ +CH + + Sbjct: 118 IVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNI 177 Query: 425 YHRDIKPDNLLVDEHGNLK 481 HRD+K +NLL+D N+K Sbjct: 178 VHRDLKAENLLLDAEANIK 196
>MARK4_HUMAN (Q96L34) MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase-like 1) Length = 752 Score = 129 bits (325), Expect = 3e-30 Identities = 60/139 (43%), Positives = 99/139 (71%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 Y ++ +G+GNFAKV LARH+ T EVAIK++DK +L ++Q++ RE+ +M+ L HPN Sbjct: 59 YRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQL-NPSSLQKLFREVRIMKGLNHPN 117 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 IV+L +V+ + +++VMEY G ++ ++ ++G +KE E R F+Q+VSA+ +CH + + Sbjct: 118 IVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNI 177 Query: 425 YHRDIKPDNLLVDEHGNLK 481 HRD+K +NLL+D N+K Sbjct: 178 VHRDLKAENLLLDAEANIK 196
>SN1L1_MOUSE (Q60670) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (HRT-20) (Myocardial SNF1-like kinase) Length = 779 Score = 129 bits (325), Expect = 3e-30 Identities = 63/157 (40%), Positives = 104/157 (66%) Frame = +2 Query: 11 AQESGDGAMGDRPKLPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGA 190 A SG G +P Y+ + LG+GNFA V LARH TK +VAIK++DK +L Sbjct: 9 AVPSGTGQGQQKPLRVGFYDVERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSN- 67 Query: 191 VQQIKREIAVMRRLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETR 370 +++I RE+ +M+ L HPNI++L++VM K +++V E+ + G ++ ++ +NG L E+E R Sbjct: 68 LEKIYREVQLMKLLNHPNIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEAR 127 Query: 371 RIFQQLVSALTFCHAQGVYHRDIKPDNLLVDEHGNLK 481 + F Q++SA+ +CH + HRD+K +NLL+D + ++K Sbjct: 128 QKFWQILSAVEYCHNHHIVHRDLKTENLLLDSNMDIK 164
>KIN11_ARATH (P92958) SNF1-related protein kinase catalytic alpha subunit KIN11| (EC 2.7.11.1) (AKIN11) (AKIN alpha1) Length = 512 Score = 129 bits (324), Expect = 4e-30 Identities = 59/139 (42%), Positives = 95/139 (68%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 Y+ K LG G+F KV +A H+ T +VAIK++++ K+ + ++++REI ++R HP+ Sbjct: 20 YKLGKTLGIGSFGKVKIAEHVVTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFMHPH 79 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 I++ ++V+ S I+VVMEYV+ G L+ +I G L+EDE R FQQ++S + +CH V Sbjct: 80 IIRQYEVIETTSDIYVVMEYVKSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHRNMV 139 Query: 425 YHRDIKPDNLLVDEHGNLK 481 HRD+KP+NLL+D N+K Sbjct: 140 VHRDLKPENLLLDSRCNIK 158
>MARK1_HUMAN (Q9P0L2) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) Length = 795 Score = 129 bits (324), Expect = 4e-30 Identities = 64/150 (42%), Positives = 104/150 (69%) Frame = +2 Query: 32 AMGDRPKLPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKRE 211 A ++P + Y K +G+GNFAKV LARH+ T EVA+K++DK +L ++Q++ RE Sbjct: 50 ATDEQPHI-GNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPT-SLQKLFRE 107 Query: 212 IAVMRRLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLV 391 + +M+ L HPNIV+L +V+ + +++VMEY GG ++ ++ A+G +KE E R F+Q+V Sbjct: 108 VRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIV 167 Query: 392 SALTFCHAQGVYHRDIKPDNLLVDEHGNLK 481 SA+ +CH + + HRD+K +NLL+D N+K Sbjct: 168 SAVQYCHQKYIVHRDLKAENLLLDGDMNIK 197
>AAPK2_PONPY (Q5RD00) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 128 bits (321), Expect = 9e-30 Identities = 59/133 (44%), Positives = 94/133 (70%) Frame = +2 Query: 83 LGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPNIVQLHK 262 LG G F KV + H T +VA+K+++++K+ L V +IKREI ++ RHP+I++L++ Sbjct: 22 LGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQ 81 Query: 263 VMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGVYHRDIK 442 V++ + F+VMEYV GG L+ +I +G ++E E RR+FQQ++SA+ +CH V HRD+K Sbjct: 82 VISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDLK 141 Query: 443 PDNLLVDEHGNLK 481 P+N+L+D H N K Sbjct: 142 PENVLLDAHMNAK 154
>AAPK2_HUMAN (P54646) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 128 bits (321), Expect = 9e-30 Identities = 59/133 (44%), Positives = 94/133 (70%) Frame = +2 Query: 83 LGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPNIVQLHK 262 LG G F KV + H T +VA+K+++++K+ L V +IKREI ++ RHP+I++L++ Sbjct: 22 LGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQ 81 Query: 263 VMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGVYHRDIK 442 V++ + F+VMEYV GG L+ +I +G ++E E RR+FQQ++SA+ +CH V HRD+K Sbjct: 82 VISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDLK 141 Query: 443 PDNLLVDEHGNLK 481 P+N+L+D H N K Sbjct: 142 PENVLLDAHMNAK 154
>SN1L1_RAT (Q9R1U5) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (Salt-inducible protein kinase) (Protein kinase KID2) Length = 776 Score = 128 bits (321), Expect = 9e-30 Identities = 62/157 (39%), Positives = 104/157 (66%) Frame = +2 Query: 11 AQESGDGAMGDRPKLPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGA 190 A +G G +P Y+ + LG+GNFA V LARH TK +VAIK++DK +L Sbjct: 9 AVPTGTGQGQQKPLRVGFYDVERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSN- 67 Query: 191 VQQIKREIAVMRRLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETR 370 +++I RE+ +M+ L HPNI++L++VM K +++V E+ + G ++ ++ +NG L E+E R Sbjct: 68 LEKIYREVQLMKLLNHPNIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEAR 127 Query: 371 RIFQQLVSALTFCHAQGVYHRDIKPDNLLVDEHGNLK 481 + F Q++SA+ +CH + HRD+K +NLL+D + ++K Sbjct: 128 KKFWQILSAVEYCHNHHIVHRDLKTENLLLDGNMDIK 164
>SN1L2_MOUSE (Q8CFH6) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Salt-inducible kinase 2) Length = 931 Score = 127 bits (319), Expect = 2e-29 Identities = 61/139 (43%), Positives = 97/139 (69%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 Y+ LG+GNFA V L RH TK EVAIK++DK +L + +++I RE+ +M+ L HP+ Sbjct: 20 YDIEGTLGKGNFAVVKLGRHRTTKTEVAIKIIDKSQLDAVN-LEKIYREVQIMKMLDHPH 78 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 I++L++VM KS +++V EY + G ++ ++ +G L E E RR F Q++SA+ +CH + V Sbjct: 79 IIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKV 138 Query: 425 YHRDIKPDNLLVDEHGNLK 481 HRD+K +NLL+D + N+K Sbjct: 139 VHRDLKAENLLLDNNMNIK 157
>MARK2_MOUSE (Q05512) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1) Length = 776 Score = 127 bits (319), Expect = 2e-29 Identities = 60/139 (43%), Positives = 99/139 (71%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 Y +K +G+GNFAKV LARH+ T +EVA+K++DK +L ++Q++ RE+ +M+ L HPN Sbjct: 53 YRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQL-NSSSLQKLFREVRIMKVLNHPN 111 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 IV+L +V+ + +++VMEY GG ++ ++ A+G +KE E R F+Q+V + +CH + + Sbjct: 112 IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVLHVQYCHQKFI 171 Query: 425 YHRDIKPDNLLVDEHGNLK 481 HRD+K +NLL+D N+K Sbjct: 172 VHRDLKAENLLLDADMNIK 190
>MELK_MOUSE (Q61846) Maternal embryonic leucine zipper kinase (EC 2.7.11.1)| (Protein kinase PK38) (mPK38) Length = 643 Score = 127 bits (319), Expect = 2e-29 Identities = 68/149 (45%), Positives = 99/149 (66%) Frame = +2 Query: 35 MGDRPKLPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREI 214 M D +L YE + +G G FAKV LA H+ T E VAIK+MDK L + ++K EI Sbjct: 1 MKDYDELLKYYELYETIGTGGFAKVKLACHVLTGEMVAIKIMDKNALGS--DLPRVKTEI 58 Query: 215 AVMRRLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVS 394 ++ LRH +I QL+ V+ K++IF+V+EY GG L+ +I + L E+ETR +F+Q++S Sbjct: 59 DALKSLRHQHICQLYHVLETKNKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQILS 118 Query: 395 ALTFCHAQGVYHRDIKPDNLLVDEHGNLK 481 A+ + H+QG HRD+KP+NLL DE+ LK Sbjct: 119 AVAYVHSQGYAHRDLKPENLLFDENHKLK 147
>AAPK2_CAEEL (Q95ZQ4) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMP-activated kinase 2) Length = 626 Score = 127 bits (319), Expect = 2e-29 Identities = 59/133 (44%), Positives = 93/133 (69%) Frame = +2 Query: 83 LGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPNIVQLHK 262 LG G F KV + H T+ +VA+K+++++K+ L V +I+REI + RHP+I++L++ Sbjct: 93 LGVGTFGKVKVGIHETTQYKVAVKILNRQKIKSLDVVGKIRREIQNLSLFRHPHIIRLYQ 152 Query: 263 VMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGVYHRDIK 442 V++ S IF++ME+V GG L+ +I +G LK E RR FQQ++S + +CH V HRD+K Sbjct: 153 VISTPSDIFMIMEHVSGGELFDYIVKHGRLKTAEARRFFQQIISGVDYCHRHMVVHRDLK 212 Query: 443 PDNLLVDEHGNLK 481 P+NLL+DE N+K Sbjct: 213 PENLLLDEQNNVK 225
>KIN10_ARATH (Q38997) SNF1-related protein kinase catalytic alpha subunit KIN10| (EC 2.7.11.1) (AKIN10) (AKIN alpha2) Length = 535 Score = 127 bits (319), Expect = 2e-29 Identities = 59/154 (38%), Positives = 99/154 (64%) Frame = +2 Query: 20 SGDGAMGDRPKLPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQ 199 SG G+ + Y+ + LG G+F +V +A H T +VAIK++++ K+ + ++ Sbjct: 27 SGTGSRSGVESILPNYKLGRTLGIGSFGRVKIAEHALTGHKVAIKILNRRKIKNMEMEEK 86 Query: 200 IKREIAVMRRLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIF 379 ++REI ++R HP+I++L++V+ + I++VMEYV G L+ +I G L+EDE R F Sbjct: 87 VRREIKILRLFMHPHIIRLYEVIETPTDIYLVMEYVNSGELFDYIVEKGRLQEDEARNFF 146 Query: 380 QQLVSALTFCHAQGVYHRDIKPDNLLVDEHGNLK 481 QQ++S + +CH V HRD+KP+NLL+D N+K Sbjct: 147 QQIISGVEYCHRNMVVHRDLKPENLLLDSKCNVK 180
>MELK_HUMAN (Q14680) Maternal embryonic leucine zipper kinase (EC 2.7.11.1)| (hMELK) (Protein kinase PK38) (hPK38) Length = 651 Score = 127 bits (318), Expect = 2e-29 Identities = 69/149 (46%), Positives = 98/149 (65%) Frame = +2 Query: 35 MGDRPKLPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREI 214 M D +L YE + +G G FAKV LA H+ T E VAIK+MDK L + +IK EI Sbjct: 1 MKDYDELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGS--DLPRIKTEI 58 Query: 215 AVMRRLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVS 394 ++ LRH +I QL+ V+ ++IF+V+EY GG L+ +I + L E+ETR +F+Q+VS Sbjct: 59 EALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVS 118 Query: 395 ALTFCHAQGVYHRDIKPDNLLVDEHGNLK 481 A+ + H+QG HRD+KP+NLL DE+ LK Sbjct: 119 AVAYVHSQGYAHRDLKPENLLFDEYHKLK 147
>SN1L1_HUMAN (P57059) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) Length = 783 Score = 127 bits (318), Expect = 2e-29 Identities = 61/157 (38%), Positives = 104/157 (66%) Frame = +2 Query: 11 AQESGDGAMGDRPKLPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGA 190 A +G G +P Y+ + LG+GNFA V LARH TK +VAIK++DK +L Sbjct: 9 ADPAGQGQGQQKPLRVGFYDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSN- 67 Query: 191 VQQIKREIAVMRRLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETR 370 +++I RE+ +M+ L HP+I++L++VM K +++V E+ + G ++ ++ +NG L E+E R Sbjct: 68 LEKIYREVQLMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEAR 127 Query: 371 RIFQQLVSALTFCHAQGVYHRDIKPDNLLVDEHGNLK 481 + F Q++SA+ +CH + HRD+K +NLL+D + ++K Sbjct: 128 KKFWQILSAVEYCHDHHIVHRDLKTENLLLDGNMDIK 164
>SN1L2_HUMAN (Q9H0K1) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Qin-induced kinase) Length = 926 Score = 126 bits (316), Expect = 3e-29 Identities = 60/139 (43%), Positives = 97/139 (69%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 Y+ LG+GNFA V L RH TK EVAIK++DK +L + +++I RE+ +M+ L HP+ Sbjct: 20 YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVN-LEKIYREVQIMKMLDHPH 78 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 I++L++VM KS +++V EY + G ++ ++ +G L E E RR F Q++SA+ +CH + + Sbjct: 79 IIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKI 138 Query: 425 YHRDIKPDNLLVDEHGNLK 481 HRD+K +NLL+D + N+K Sbjct: 139 VHRDLKAENLLLDNNMNIK 157
>SN1L2_PONPY (Q5REX1) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) Length = 925 Score = 126 bits (316), Expect = 3e-29 Identities = 60/139 (43%), Positives = 97/139 (69%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 Y+ LG+GNFA V L RH TK EVAIK++DK +L + +++I RE+ +M+ L HP+ Sbjct: 20 YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVN-LEKIYREVQIMKMLDHPH 78 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 I++L++VM KS +++V EY + G ++ ++ +G L E E RR F Q++SA+ +CH + + Sbjct: 79 IIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKI 138 Query: 425 YHRDIKPDNLLVDEHGNLK 481 HRD+K +NLL+D + N+K Sbjct: 139 VHRDLKAENLLLDNNMNIK 157
>AAPK2_RAT (Q09137) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 125 bits (313), Expect = 8e-29 Identities = 58/133 (43%), Positives = 93/133 (69%) Frame = +2 Query: 83 LGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPNIVQLHK 262 LG G F KV + H T +VA+K+++++K+ L V +IKREI ++ RHP+I++L++ Sbjct: 22 LGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQ 81 Query: 263 VMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGVYHRDIK 442 V++ + F+VMEYV GG L+ +I +G ++E E RR+FQQ++SA+ +CH V HRD+K Sbjct: 82 VISTPTDFFMVMEYVSGGELFDYICKHGRVEEVEARRLFQQILSAVDYCHRHMVVHRDLK 141 Query: 443 PDNLLVDEHGNLK 481 P+N+L+D N K Sbjct: 142 PENVLLDAQMNAK 154
>AAPK2_PIG (Q28948) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 125 bits (313), Expect = 8e-29 Identities = 58/133 (43%), Positives = 93/133 (69%) Frame = +2 Query: 83 LGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPNIVQLHK 262 LG G F KV + H T +VA+K+++++K+ L V +IKREI ++ RHP+I++L++ Sbjct: 22 LGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQ 81 Query: 263 VMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGVYHRDIK 442 V++ + F+VMEYV GG L+ +I +G ++E E RR+FQQ++SA+ +CH V HRD+K Sbjct: 82 VISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDLK 141 Query: 443 PDNLLVDEHGNLK 481 P+N+L+D N K Sbjct: 142 PENVLLDAQMNAK 154
>RKIN1_SECCE (Q02723) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 502 Score = 122 bits (305), Expect = 6e-28 Identities = 63/151 (41%), Positives = 96/151 (63%), Gaps = 3/151 (1%) Frame = +2 Query: 38 GDRPKLPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIA 217 G+ + Y K+LG G FAKV +A H T+ +VAIKV+++ ++ ++ KREI Sbjct: 5 GEHSEALKNYYLGKILGVGTFAKVIIAEHKHTRHKVAIKVLNRRQMRAPEMEEKAKREIK 64 Query: 218 VMRR---LRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQL 388 ++R L HP+I+++++V+ IFVVMEY + G L +I L+EDE RR FQQ+ Sbjct: 65 ILRLFIDLIHPHIIRVYEVIVTPKDIFVVMEYCQNGDLLDYILEKRRLQEDEARRTFQQI 124 Query: 389 VSALTFCHAQGVYHRDIKPDNLLVDEHGNLK 481 +SA+ +CH V HRD+KP+NLL+D N+K Sbjct: 125 ISAVEYCHRNKVVHRDLKPENLLLDSKYNVK 155
>BRSK1_HUMAN (Q8TDC3) BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1| kinase) (SAD1A) Length = 794 Score = 120 bits (302), Expect = 1e-27 Identities = 56/139 (40%), Positives = 94/139 (67%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 Y K LG+G V L H T ++VAIK++++EKL + + +++REIA+++ + HP+ Sbjct: 50 YRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSE-SVLMKVEREIAILKLIEHPH 108 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 +++LH V K +++V+E+V GG L+ ++ G L E R+ F+Q+VSAL FCH+ + Sbjct: 109 VLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSI 168 Query: 425 YHRDIKPDNLLVDEHGNLK 481 HRD+KP+NLL+DE N++ Sbjct: 169 CHRDLKPENLLLDEKNNIR 187
>BRSK2_HUMAN (Q8IWQ3) BR serine/threonine-protein kinase 2 (EC 2.7.11.1)| (Serine/threonine-protein kinase 29) (SAD1B) Length = 736 Score = 120 bits (301), Expect = 2e-27 Identities = 55/139 (39%), Positives = 94/139 (67%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 Y K LG+G V L H T ++VAIK++++EKL + + +++REIA+++ + HP+ Sbjct: 19 YRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSE-SVLMKVEREIAILKLIEHPH 77 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 +++LH V K +++V+E+V GG L+ ++ G L E R+ F+Q++SAL FCH+ + Sbjct: 78 VLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSI 137 Query: 425 YHRDIKPDNLLVDEHGNLK 481 HRD+KP+NLL+DE N++ Sbjct: 138 CHRDLKPENLLLDEKNNIR 156
>AURKB_MOUSE (O70126) Serine/threonine-protein kinase 12 (EC 2.7.11.1)| (Aurora-related kinase 2) (Serine/threonine-protein kinase 5) (STK-1) (Aurora-B) Length = 345 Score = 118 bits (295), Expect = 9e-27 Identities = 58/160 (36%), Positives = 93/160 (58%) Frame = +2 Query: 2 RTPAQESGDGAMGDRPKLPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIK 181 ++ + G+ +P +E + LG+G F VYLAR ++ VA+K++ K ++ K Sbjct: 61 KSQGSTASQGSQNKQPFTIDNFEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQIEK 120 Query: 182 LGAVQQIKREIAVMRRLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKED 361 G Q++REI + L+HPNI+QL+ + RI++++EY G LY+ + + E Sbjct: 121 EGVEHQLRREIEIQAHLKHPNILQLYNYFYDQQRIYLILEYAPRGELYKELQKSRTFDEQ 180 Query: 362 ETRRIFQQLVSALTFCHAQGVYHRDIKPDNLLVDEHGNLK 481 T I ++L ALT+CH + V HRDIKP+NLL+ G LK Sbjct: 181 RTATIMEELSDALTYCHKKKVIHRDIKPENLLLGLQGELK 220
>AURKB_RAT (O55099) Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-| and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora-B) Length = 343 Score = 117 bits (294), Expect = 1e-26 Identities = 58/151 (38%), Positives = 90/151 (59%) Frame = +2 Query: 29 GAMGDRPKLPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKR 208 G+ +P +E + LG+G F VYLAR ++ VA+K++ K ++ K G Q++R Sbjct: 68 GSQSRQPFTIDNFEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQIEKEGVEHQLRR 127 Query: 209 EIAVMRRLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQL 388 EI + L+HPNI+QL+ + RI++++EY G LY+ + +G E T I ++L Sbjct: 128 EIEIQAHLKHPNILQLYNYFYDQQRIYLILEYAPRGELYKELQKSGTFDEQRTATIMEEL 187 Query: 389 VSALTFCHAQGVYHRDIKPDNLLVDEHGNLK 481 AL +CH + V HRDIKP+NLL+ G LK Sbjct: 188 SDALMYCHKKKVIHRDIKPENLLLGLQGELK 218
>MARK3_HUMAN (P27448) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| (Cdc25C-associated protein kinase 1) (cTAK1) (C-TAK1) (Serine/threonine protein kinase p78) (Ser/Thr protein kinase PAR-1) (Protein kinase STK10) Length = 776 Score = 117 bits (294), Expect = 1e-26 Identities = 62/162 (38%), Positives = 100/162 (61%), Gaps = 23/162 (14%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 Y +K +G+GNFAKV LARH+ T EVAIK++DK +L ++Q++ RE+ +M+ L HPN Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPT-SLQKLFREVRIMKILNHPN 114 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQ------------- 385 IV+L +V+ + ++++MEY GG ++ ++ A+G +KE E R F+Q Sbjct: 115 IVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQGCQAGQTIKVQVS 174 Query: 386 ----------LVSALTFCHAQGVYHRDIKPDNLLVDEHGNLK 481 +VSA+ +CH + + HRD+K +NLL+D N+K Sbjct: 175 FDLLSLMFTFIVSAVQYCHQKRIVHRDLKAENLLLDADMNIK 216
>SNF1_SCHPO (O74536) SNF1-like protein kinase ssp2 (EC 2.7.11.1)| Length = 576 Score = 117 bits (294), Expect = 1e-26 Identities = 56/133 (42%), Positives = 92/133 (69%) Frame = +2 Query: 83 LGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPNIVQLHK 262 LGEG+F KV LA H T+++VA+K + ++ L K +++REI+ ++ LRHP+I++L+ Sbjct: 40 LGEGSFGKVKLATHYKTQQKVALKFISRQLLKKSDMHMRVEREISYLKLLRHPHIIKLYD 99 Query: 263 VMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGVYHRDIK 442 V+ + I +V+EY GG L+ +I + EDE RR FQQ++ A+ +CH + HRD+K Sbjct: 100 VITTPTDIVMVIEYA-GGELFDYIVEKKRMTEDEGRRFFQQIICAIEYCHRHKIVHRDLK 158 Query: 443 PDNLLVDEHGNLK 481 P+NLL+D++ N+K Sbjct: 159 PENLLLDDNLNVK 171
>AAPK1_CAEEL (P45894) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMP-activated kinase 1) Length = 589 Score = 115 bits (289), Expect = 5e-26 Identities = 54/133 (40%), Positives = 89/133 (66%) Frame = +2 Query: 83 LGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPNIVQLHK 262 +G+G F V H+ T +VAIK++++ ++ LG V + + EI +++L HP+I +L + Sbjct: 30 IGKGAFGAVKRGTHIQTGYDVAIKILNRGRMKGLGTVNKTRNEIDNLQKLTHPHITRLFR 89 Query: 263 VMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGVYHRDIK 442 V++ S IF+VME V GG L+ +I G L E+RR FQQ++S +++CH + HRD+K Sbjct: 90 VISTPSDIFLVMELVSGGELFSYITRKGALPIRESRRYFQQIISGVSYCHNHMIVHRDLK 149 Query: 443 PDNLLVDEHGNLK 481 P+NLL+D + N+K Sbjct: 150 PENLLLDANKNIK 162
>STK6_XENLA (Q91820) Serine/threonine-protein kinase Eg2 (EC 2.7.11.1) (pEg2)| (p46Eg265) Length = 407 Score = 114 bits (285), Expect = 1e-25 Identities = 54/139 (38%), Positives = 87/139 (62%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 +E + LG+G F VYLAR ++K +A+KV+ K +L K G Q++RE+ + LRHPN Sbjct: 140 FEIGRPLGKGKFGNVYLARERESKFILALKVLFKSQLEKAGVEHQLRREVEIQSHLRHPN 199 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 I++L+ SR++++++Y GG L+R + + + +QL AL +CH++ V Sbjct: 200 ILRLYGYFHDASRVYLILDYAPGGELFRELQKCTRFDDQRSAMYIKQLAEALLYCHSKKV 259 Query: 425 YHRDIKPDNLLVDEHGNLK 481 HRDIKP+NLL+ +G LK Sbjct: 260 IHRDIKPENLLLGSNGELK 278
>STK6L_XENLA (Q91819) Serine/threonine-protein kinase Eg2-like (EC 2.7.11.1)| (p46XlEg22) Length = 408 Score = 114 bits (284), Expect = 2e-25 Identities = 54/139 (38%), Positives = 87/139 (62%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 +E + LG+G F VYLAR ++K +A+KV+ K +L K G Q++RE+ + LRHPN Sbjct: 140 FEIGRPLGKGKFGNVYLARERESKFILALKVLFKSQLEKAGVEHQLRREVEIQSHLRHPN 199 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 I++L+ SR++++++Y GG L+R + + + +QL AL +CH++ V Sbjct: 200 ILRLYGYFHDASRVYLILDYAPGGELFRELQKCTRFDDQRSALYIKQLAEALLYCHSKKV 259 Query: 425 YHRDIKPDNLLVDEHGNLK 481 HRDIKP+NLL+ +G LK Sbjct: 260 IHRDIKPENLLLGSNGELK 278
>NUAK1_HUMAN (O60285) NUAK family, SNF1-like kinase 1 (EC 2.7.11.1)| (AMPK-related protein kinase 5) Length = 661 Score = 114 bits (284), Expect = 2e-25 Identities = 58/143 (40%), Positives = 88/143 (61%) Frame = +2 Query: 53 LPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRL 232 L RYE + LG+G + KV A + VAIK + K+K+ + I+REI +M L Sbjct: 51 LKHRYELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSL 110 Query: 233 RHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCH 412 HP+I+ +++V K +I ++MEY G LY +I L E ETR F+Q+VSA+ +CH Sbjct: 111 NHPHIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCH 170 Query: 413 AQGVYHRDIKPDNLLVDEHGNLK 481 GV HRD+K +N+L+D++ N+K Sbjct: 171 KNGVVHRDLKLENILLDDNCNIK 193
>CDS1_SCHPO (Q09170) Serine/threonine-protein kinase cds1 (EC 2.7.11.1)| (Checkpoint kinase cds1) Length = 460 Score = 113 bits (282), Expect = 3e-25 Identities = 58/164 (35%), Positives = 93/164 (56%), Gaps = 4/164 (2%) Frame = +2 Query: 2 RTPAQESGDGAMGDRPKLPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIK 181 + P + S D + YE ++ LG G FA V LA +++ + AIK+++K K++ Sbjct: 146 QVPVKHSRDSQKNMIKSENSHYEIIRTLGSGTFAVVKLAVEVNSGKWYAIKIINKRKILL 205 Query: 182 LG----AVQQIKREIAVMRRLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGG 349 A + +REI +++ L HP +VQ H++ +F+VMEYV GG L + ANG Sbjct: 206 TSSEKRATEMFQREIDILKSLHHPGVVQCHEIFENDDELFIVMEYVEGGDLMDFLIANGS 265 Query: 350 LKEDETRRIFQQLVSALTFCHAQGVYHRDIKPDNLLVDEHGNLK 481 + E + + + +QL+ L H QGV HRDIKP+N+L+ +LK Sbjct: 266 IDEQDCKPLLKQLLETLLHLHKQGVTHRDIKPENILITNDFHLK 309
>NUAK1_MOUSE (Q641K5) NUAK family, SNF1-like kinase 1 (EC 2.7.11.1)| Length = 658 Score = 113 bits (282), Expect = 3e-25 Identities = 58/143 (40%), Positives = 88/143 (61%) Frame = +2 Query: 53 LPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRL 232 L RYE + LG+G + KV A + VAIK + K+K+ + I+REI +M L Sbjct: 52 LKHRYELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDELDMVHIRREIEIMSSL 111 Query: 233 RHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCH 412 HP+I+ +++V K +I ++MEY G LY +I L E ETR F+Q+VSA+ +CH Sbjct: 112 NHPHIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCH 171 Query: 413 AQGVYHRDIKPDNLLVDEHGNLK 481 GV HRD+K +N+L+D++ N+K Sbjct: 172 KNGVVHRDLKLENILLDDNCNIK 194
>AURKC_MOUSE (O88445) Serine/threonine-protein kinase 13 (EC 2.7.11.1)| (Aurora/Ipl1/Eg2 protein 1) (Aurora-C) Length = 282 Score = 112 bits (279), Expect = 7e-25 Identities = 55/139 (39%), Positives = 87/139 (62%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 +E + LG G F +VYLAR + VA+KV+ K ++ K G Q++RE+ + L+H N Sbjct: 16 FEIGRPLGRGKFGRVYLARLKENHFIVALKVLFKSEIEKEGLEHQLRREVEIQAHLQHRN 75 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 I++L+ +RI++++EY GG LY+ + + L + T I Q+L ALT+CH + V Sbjct: 76 ILRLYNYFYDDTRIYLILEYAPGGELYKELQRHQKLDQQRTATIIQELSDALTYCHEKKV 135 Query: 425 YHRDIKPDNLLVDEHGNLK 481 HRDIKP+NLL+ +G +K Sbjct: 136 IHRDIKPENLLLGLNGEVK 154
>AURKC_HUMAN (Q9UQB9) Serine/threonine-protein kinase 13 (EC 2.7.11.1)| (Aurora/Ipl1/Eg2 protein 2) (Aurora/Ipl1-related kinase 3) (Aurora-C) Length = 309 Score = 111 bits (278), Expect = 9e-25 Identities = 55/139 (39%), Positives = 86/139 (61%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 +E + LG+G F VYLAR ++ VA+KV+ K ++ K G Q++REI + L+HPN Sbjct: 43 FEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPN 102 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 I++L+ R+++++EY G LY+ + + L E T I ++L ALT+CH + V Sbjct: 103 ILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKV 162 Query: 425 YHRDIKPDNLLVDEHGNLK 481 HRDIKP+NLL+ G +K Sbjct: 163 IHRDIKPENLLLGFRGEVK 181
>STK6_RAT (P59241) Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Aurora-A)| (ratAurA) Length = 397 Score = 111 bits (278), Expect = 9e-25 Identities = 53/133 (39%), Positives = 83/133 (62%) Frame = +2 Query: 83 LGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPNIVQLHK 262 LG+G F VYLAR +K +A+KV+ K +L K G Q++RE+ + LRHPNI++L+ Sbjct: 132 LGKGKFGNVYLAREKQSKFILALKVLFKVQLEKAGVEHQLRREVEIQSHLRHPNILRLYG 191 Query: 263 VMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGVYHRDIK 442 +R+++++EY G +YR + E T +L +AL++CH++ V HRDIK Sbjct: 192 YFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIK 251 Query: 443 PDNLLVDEHGNLK 481 P+NLL+ +G LK Sbjct: 252 PENLLLGSNGELK 264
>STK6_HUMAN (O14965) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1) (Aurora-related kinase 1) (hARK1) (Aurora-A) (Breast-tumor-amplified kinase) Length = 403 Score = 111 bits (277), Expect = 1e-24 Identities = 54/139 (38%), Positives = 85/139 (61%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 +E + LG+G F VYLAR +K +A+KV+ K +L K G Q++RE+ + LRHPN Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 I++L+ +R+++++EY G +YR + E T +L +AL++CH++ V Sbjct: 193 ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRV 252 Query: 425 YHRDIKPDNLLVDEHGNLK 481 HRDIKP+NLL+ G LK Sbjct: 253 IHRDIKPENLLLGSAGELK 271
>AURKB_HUMAN (Q96GD4) Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-| and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (Aurora-related kinase 2) (STK-1) (Aurora-B) Length = 344 Score = 110 bits (275), Expect = 2e-24 Identities = 55/139 (39%), Positives = 83/139 (59%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 +E + LG+G F VYLAR + VA+KV+ K ++ K G Q++REI + L HPN Sbjct: 77 FEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPN 136 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 I++L+ + RI++++EY G LY+ + + E T I ++L AL +CH + V Sbjct: 137 ILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKV 196 Query: 425 YHRDIKPDNLLVDEHGNLK 481 HRDIKP+NLL+ G LK Sbjct: 197 IHRDIKPENLLLGLKGELK 215
>SNRK_MOUSE (Q8VDU5) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 748 Score = 109 bits (273), Expect = 3e-24 Identities = 57/144 (39%), Positives = 96/144 (66%), Gaps = 1/144 (0%) Frame = +2 Query: 50 KLPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRR 229 K+ Y+ K LG G+FA V LARH+ T E+VA+KV+DK KL L A + +E+ M+ Sbjct: 11 KIAGLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTL-ATGHLFQEVRCMKL 69 Query: 230 LRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPAN-GGLKEDETRRIFQQLVSALTF 406 ++HPNIV+L++V+ ++++++++E GG ++ +I + GL ED ++ F Q+V A+++ Sbjct: 70 VQHPNIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISY 129 Query: 407 CHAQGVYHRDIKPDNLLVDEHGNL 478 CH V HRD+KP+N++ E L Sbjct: 130 CHKLHVVHRDLKPENVVFFEKQGL 153
>SAPK2_ORYSA (Q84TC6) Serine/threonine-protein kinase SAPK2 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 2) Length = 339 Score = 109 bits (273), Expect = 3e-24 Identities = 55/134 (41%), Positives = 83/134 (61%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHP 241 RYE +K +G GNF L R + TKE A+K +++ + I + ++REI R LRHP Sbjct: 3 RYEVIKDIGSGNFGVAKLVRDVRTKELFAVKFIERGQKID----ENVQREIMNHRSLRHP 58 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 NIV+ +V+ + + +VMEY GG L+ I + G EDE R FQQL+S +++CH+ Sbjct: 59 NIVRFKEVVLTPTHLAIVMEYAAGGELFERICSAGRFSEDEARFFFQQLISGVSYCHSMQ 118 Query: 422 VYHRDIKPDNLLVD 463 + HRD+K +N L+D Sbjct: 119 ICHRDLKLENTLLD 132
>STK6_MOUSE (P97477) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Aurora-family kinase 1) (Aurora/IPL1-related kinase 1) (Ipl1- and aurora-related kinase 1) (Aurora-A) (Serine/threonine-protein kinase Ayk1) Length = 395 Score = 109 bits (273), Expect = 3e-24 Identities = 52/133 (39%), Positives = 82/133 (61%) Frame = +2 Query: 83 LGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPNIVQLHK 262 LG+G F VYLAR +K +A+KV+ K +L K Q++RE+ + LRHPNI++L+ Sbjct: 130 LGKGKFGNVYLARERQSKFILALKVLFKTQLEKANVEHQLRREVEIQSHLRHPNILRLYG 189 Query: 263 VMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGVYHRDIK 442 +R+++++EY G +YR + E T +L +AL++CH++ V HRDIK Sbjct: 190 YFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIK 249 Query: 443 PDNLLVDEHGNLK 481 P+NLL+ +G LK Sbjct: 250 PENLLLGSNGELK 262
>SNRK_HUMAN (Q9NRH2) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 765 Score = 109 bits (273), Expect = 3e-24 Identities = 57/144 (39%), Positives = 96/144 (66%), Gaps = 1/144 (0%) Frame = +2 Query: 50 KLPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRR 229 K+ Y+ K LG G+FA V LARH+ T E+VA+KV+DK KL L A + +E+ M+ Sbjct: 11 KIAGLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTL-ATGHLFQEVRCMKL 69 Query: 230 LRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPAN-GGLKEDETRRIFQQLVSALTF 406 ++HPNIV+L++V+ ++++++++E GG ++ +I + GL ED ++ F Q+V A+++ Sbjct: 70 VQHPNIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISY 129 Query: 407 CHAQGVYHRDIKPDNLLVDEHGNL 478 CH V HRD+KP+N++ E L Sbjct: 130 CHKLHVVHRDLKPENVVFFEKQGL 153
>SNRK_RAT (Q63553) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 746 Score = 109 bits (273), Expect = 3e-24 Identities = 57/144 (39%), Positives = 96/144 (66%), Gaps = 1/144 (0%) Frame = +2 Query: 50 KLPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRR 229 K+ Y+ K LG G+FA V LARH+ T E+VA+KV+DK KL L A + +E+ M+ Sbjct: 11 KIAGLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTL-ATGHLFQEVRCMKL 69 Query: 230 LRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPAN-GGLKEDETRRIFQQLVSALTF 406 ++HPNIV+L++V+ ++++++++E GG ++ +I + GL ED ++ F Q+V A+++ Sbjct: 70 VQHPNIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISY 129 Query: 407 CHAQGVYHRDIKPDNLLVDEHGNL 478 CH V HRD+KP+N++ E L Sbjct: 130 CHKLHVVHRDLKPENVVFFEKQGL 153
>SAPK3_ORYSA (Q75V63) Serine/threonine-protein kinase SAPK3 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 3) (Protein kinase REK) Length = 334 Score = 109 bits (272), Expect = 4e-24 Identities = 56/134 (41%), Positives = 81/134 (60%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHP 241 RYE +K LG GNF L R +KE VA+K +++ K I + ++REI R LRHP Sbjct: 4 RYEALKELGAGNFGVARLVRDKRSKELVAVKYIERGKKID----ENVQREIINHRSLRHP 59 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 NI++ +V + + +VMEY GG L+ I G EDE R FQQL+S +++CH+ Sbjct: 60 NIIRFKEVCLTPTHLAIVMEYAAGGELFEQICTAGRFSEDEARYFFQQLISGVSYCHSLE 119 Query: 422 VYHRDIKPDNLLVD 463 + HRD+K +N L+D Sbjct: 120 ICHRDLKLENTLLD 133
>SAPK9_ORYSA (Q75V57) Serine/threonine-protein kinase SAPK9 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 9) Length = 361 Score = 108 bits (269), Expect = 1e-23 Identities = 55/134 (41%), Positives = 83/134 (61%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHP 241 RYE VK +G GNF L R+ + + VA+K +D+ + I + ++REI R LRHP Sbjct: 21 RYELVKEIGSGNFGVARLMRNRASGDLVAVKYIDRGEKID----ENVQREIINHRSLRHP 76 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 NI++ +V+ + + +VMEY GG L+ I + G EDE R FQQL+S +++CH+ Sbjct: 77 NIIRFKEVILTPTHLAIVMEYASGGELFERICSAGRFSEDEARFFFQQLISGVSYCHSMQ 136 Query: 422 VYHRDIKPDNLLVD 463 V HRD+K +N L+D Sbjct: 137 VCHRDLKLENTLLD 150
>KPK19_ARATH (Q39030) Serine/threonine-protein kinase AtPK19 (EC 2.7.11.1)| (Ribosomal-protein S6 kinase homolog) Length = 471 Score = 107 bits (266), Expect = 2e-23 Identities = 50/138 (36%), Positives = 88/138 (63%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 +E +K++G+G F KVY R DT E A+KVM K+K+++ + +K E ++ ++ HP Sbjct: 140 FEVLKVVGQGAFGKVYQVRKKDTSEIYAMKVMRKDKIVEKNHAEYMKAERDILTKIDHPF 199 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 IVQL K R+++V++++ GG L+ + G +ED R ++VSA++ H +G+ Sbjct: 200 IVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHEKGI 259 Query: 425 YHRDIKPDNLLVDEHGNL 478 HRD+KP+N+L+D G++ Sbjct: 260 MHRDLKPENILMDVDGHV 277
>HUNK_PANTR (Q68UT7) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) Length = 714 Score = 106 bits (265), Expect = 3e-23 Identities = 59/134 (44%), Positives = 85/134 (63%), Gaps = 1/134 (0%) Frame = +2 Query: 83 LGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAV-QQIKREIAVMRRLRHPNIVQLH 259 LGEG+FAKV H+ T E+VAIKV+DK++ K V + ++RE + + +RHPNI QL Sbjct: 68 LGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQLL 127 Query: 260 KVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGVYHRDI 439 ++ ++ ++VME GG L I L+E E RR +QL+SA+ H GV HRD+ Sbjct: 128 DILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEHLHRAGVVHRDL 187 Query: 440 KPDNLLVDEHGNLK 481 K +NLL+DE N+K Sbjct: 188 KIENLLLDEDNNIK 201
>HUNK_HUMAN (P57058) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) (Serine/threonine-protein kinase MAK-V) (B19) Length = 714 Score = 106 bits (265), Expect = 3e-23 Identities = 59/134 (44%), Positives = 85/134 (63%), Gaps = 1/134 (0%) Frame = +2 Query: 83 LGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAV-QQIKREIAVMRRLRHPNIVQLH 259 LGEG+FAKV H+ T E+VAIKV+DK++ K V + ++RE + + +RHPNI QL Sbjct: 68 LGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQLL 127 Query: 260 KVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGVYHRDI 439 ++ ++ ++VME GG L I L+E E RR +QL+SA+ H GV HRD+ Sbjct: 128 DILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEHLHRAGVVHRDL 187 Query: 440 KPDNLLVDEHGNLK 481 K +NLL+DE N+K Sbjct: 188 KIENLLLDEDNNIK 201
>PDPK1_HUMAN (O15530) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (hPDK1) Length = 556 Score = 105 bits (263), Expect = 5e-23 Identities = 54/141 (38%), Positives = 84/141 (59%) Frame = +2 Query: 44 RPKLPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVM 223 R K P ++ K+LGEG+F+ V LAR + T E AIK+++K +IK V + RE VM Sbjct: 75 RKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVM 134 Query: 224 RRLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALT 403 RL HP V+L+ +++ + Y + G L ++I G E TR ++VSAL Sbjct: 135 SRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALE 194 Query: 404 FCHAQGVYHRDIKPDNLLVDE 466 + H +G+ HRD+KP+N+L++E Sbjct: 195 YLHGKGIIHRDLKPENILLNE 215
>PDPK1_RAT (O55173) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (Protein kinase B kinase) (PkB kinase) Length = 559 Score = 105 bits (263), Expect = 5e-23 Identities = 54/141 (38%), Positives = 84/141 (59%) Frame = +2 Query: 44 RPKLPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVM 223 R K P ++ K+LGEG+F+ V LAR + T E AIK+++K +IK V + RE VM Sbjct: 78 RKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVM 137 Query: 224 RRLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALT 403 RL HP V+L+ +++ + Y + G L ++I G E TR ++VSAL Sbjct: 138 SRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALE 197 Query: 404 FCHAQGVYHRDIKPDNLLVDE 466 + H +G+ HRD+KP+N+L++E Sbjct: 198 YLHGKGIIHRDLKPENILLNE 218
>PDPK1_MOUSE (Q9Z2A0) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (mPDK1) Length = 559 Score = 105 bits (263), Expect = 5e-23 Identities = 54/141 (38%), Positives = 84/141 (59%) Frame = +2 Query: 44 RPKLPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVM 223 R K P ++ K+LGEG+F+ V LAR + T E AIK+++K +IK V + RE VM Sbjct: 78 RKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVM 137 Query: 224 RRLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALT 403 RL HP V+L+ +++ + Y + G L ++I G E TR ++VSAL Sbjct: 138 SRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALE 197 Query: 404 FCHAQGVYHRDIKPDNLLVDE 466 + H +G+ HRD+KP+N+L++E Sbjct: 198 YLHGKGIIHRDLKPENILLNE 218
>ASK2_ARATH (P43292) Serine/threonine-protein kinase ASK2 (EC 2.7.11.1)| Length = 353 Score = 105 bits (262), Expect = 6e-23 Identities = 54/134 (40%), Positives = 80/134 (59%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHP 241 +Y+ VK LG GNF L RH DTKE VA+K +++ + I + + REI R L+HP Sbjct: 3 KYDVVKDLGAGNFGVARLLRHKDTKELVAMKYIERGRKID----ENVAREIINHRSLKHP 58 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 NI++ +V+ + + +VMEY GG L+ I G E E R FQQL+ + +CH+ Sbjct: 59 NIIRFKEVILTPTHLAIVMEYASGGELFDRICTAGRFSEAEARYFFQQLICGVDYCHSLQ 118 Query: 422 VYHRDIKPDNLLVD 463 + HRD+K +N L+D Sbjct: 119 ICHRDLKLENTLLD 132
>SAPK5_ORYSA (Q7XKA8) Serine/threonine-protein kinase SAPK5 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 5) Length = 370 Score = 105 bits (262), Expect = 6e-23 Identities = 54/134 (40%), Positives = 80/134 (59%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHP 241 +YE V+ +G GNF L R+ +T+E VA+K +++ I + + REI R LRHP Sbjct: 3 KYEPVREIGAGNFGVAKLMRNKETRELVAMKFIERGNRID----ENVFREIVNHRSLRHP 58 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 NI++ +V+ + +VMEY GG L+ I G EDE R FQQLV +++CHA Sbjct: 59 NIIRFKEVVVTGRHLAIVMEYAAGGELFERICEAGRFHEDEARYFFQQLVCGVSYCHAMQ 118 Query: 422 VYHRDIKPDNLLVD 463 + HRD+K +N L+D Sbjct: 119 ICHRDLKLENTLLD 132
>HUNK_MOUSE (O88866) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) (Serine/threonine-protein kinase MAK-V) Length = 714 Score = 105 bits (261), Expect = 8e-23 Identities = 59/134 (44%), Positives = 84/134 (62%), Gaps = 1/134 (0%) Frame = +2 Query: 83 LGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAV-QQIKREIAVMRRLRHPNIVQLH 259 LGEG+FAKV H+ T E+VAIKV+DK++ K V + ++RE + + +RHPNI QL Sbjct: 68 LGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQLL 127 Query: 260 KVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGVYHRDI 439 ++ ++ ++VME GG L I L E E RR +QL+SA+ H GV HRD+ Sbjct: 128 DILETENSYYLVMELCPGGNLMHKIYEKKRLDEAEARRYIRQLISAVEHLHRAGVVHRDL 187 Query: 440 KPDNLLVDEHGNLK 481 K +NLL+DE N+K Sbjct: 188 KIENLLLDEDNNIK 201
>IPL1_ASHGO (Q755C4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 367 Score = 105 bits (261), Expect = 8e-23 Identities = 46/141 (32%), Positives = 83/141 (58%) Frame = +2 Query: 59 ARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRH 238 A +E K+LG+G F +VY RH+++ A+K M+K+ +I+ +Q +RE+ + LRH Sbjct: 107 ADFEIGKVLGKGKFGRVYCVRHIESGFVCALKAMEKKDIIQYNIEKQFRREVEIQSSLRH 166 Query: 239 PNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQ 418 PN+ QL+ + R++++MEY+ G LY+H+ + Q+ AL + H + Sbjct: 167 PNLTQLYGYFHDEKRVYLLMEYLVNGELYKHLKGRSHFNDVVASYYVYQMADALDYMHER 226 Query: 419 GVYHRDIKPDNLLVDEHGNLK 481 + HRDIKP+N+++ + +K Sbjct: 227 NILHRDIKPENIIIGFNNTIK 247
>SAPK8_ORYSA (Q7Y0B9) Serine/threonine-protein kinase SAPK8 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 8) Length = 371 Score = 104 bits (260), Expect = 1e-22 Identities = 54/134 (40%), Positives = 80/134 (59%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHP 241 RYE V+ +G GNF L R T E VA+K +++ + I ++REI R L+HP Sbjct: 32 RYELVRDIGSGNFGVARLMRDRRTMELVAVKYIERGEKID----DNVQREIINHRSLKHP 87 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 NI++ +V+ + + +VMEY GG L+ I N EDE R FQQL+S +++CH+ Sbjct: 88 NIIRFKEVILTPTHLAIVMEYASGGELFERICKNVRFSEDEARYFFQQLISGVSYCHSMQ 147 Query: 422 VYHRDIKPDNLLVD 463 V HRD+K +N L+D Sbjct: 148 VCHRDLKLENTLLD 161
>ICL1_KLULA (Q6CWQ4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 361 Score = 104 bits (260), Expect = 1e-22 Identities = 47/139 (33%), Positives = 84/139 (60%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 +E K+LG+G F KVY +H +T A+K M+K+++++ +Q +RE+ + +H N Sbjct: 100 FEIGKILGKGKFGKVYCVKHRETGLICALKAMEKKEIVQYTIQKQFRREVEIQGSFKHKN 159 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 + QL+ + R++++MEYV G LY+ + NG L E Q+ +AL + H++ + Sbjct: 160 LTQLYGFFYDEKRVYLLMEYVYYGELYKFLKNNGPLNETLASYFVYQMANALDYMHSKNI 219 Query: 425 YHRDIKPDNLLVDEHGNLK 481 HRDIKP+N+L+ + +K Sbjct: 220 LHRDIKPENILIGFNNTIK 238
>CHK1_CHICK (Q8AYC9) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 104 bits (260), Expect = 1e-22 Identities = 51/139 (36%), Positives = 87/139 (62%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 ++ V+ LGEG + +V LA + T+E VA+K++D ++ + IK+EI + + L H N Sbjct: 9 WDLVQTLGEGAYGEVQLAVNRRTEEAVAVKIVDMKRAAD--CPENIKKEICINKMLNHEN 66 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 +V+ + + ++ +EY GG L+ I + G+ E E +R FQQL++ + + H+ G+ Sbjct: 67 VVKFYGHRREGATQYLFLEYCSGGELFDRIEPDIGMPEPEAQRFFQQLIAGVVYLHSMGI 126 Query: 425 YHRDIKPDNLLVDEHGNLK 481 HRD+KP+NLL+DE NLK Sbjct: 127 THRDLKPENLLLDERDNLK 145
>ASK1_ARATH (P43291) Serine/threonine-protein kinase ASK1 (EC 2.7.11.1)| Length = 363 Score = 104 bits (259), Expect = 1e-22 Identities = 53/134 (39%), Positives = 81/134 (60%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHP 241 +YE VK +G GNF L + ++KE VA+K +++ I + + REI R LRHP Sbjct: 3 KYELVKDIGAGNFGVARLMKVKNSKELVAMKYIERGPKID----ENVAREIINHRSLRHP 58 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 NI++ +V+ + + + MEY GG L+ I + G EDE R FQQL+S +++CHA Sbjct: 59 NIIRFKEVVLTPTHLAIAMEYAAGGELFERICSAGRFSEDEARYFFQQLISGVSYCHAMQ 118 Query: 422 VYHRDIKPDNLLVD 463 + HRD+K +N L+D Sbjct: 119 ICHRDLKLENTLLD 132
>KAPCA_BOVIN (P00517) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 104 bits (259), Expect = 1e-22 Identities = 46/140 (32%), Positives = 85/140 (60%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHP 241 ++E++K LG G+F +V L +HM+T A+K++DK+K++KL ++ E +++ + P Sbjct: 42 QFERIKTLGTGSFGRVMLVKHMETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFP 101 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 +V+L S +++VMEYV GG ++ H+ G E R Q+V + H+ Sbjct: 102 FLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLD 161 Query: 422 VYHRDIKPDNLLVDEHGNLK 481 + +RD+KP+NLL+D+ G ++ Sbjct: 162 LIYRDLKPENLLIDQQGYIQ 181
>KAPC_DROME (P12370) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) (PKA C) Length = 352 Score = 103 bits (258), Expect = 2e-22 Identities = 48/139 (34%), Positives = 84/139 (60%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 +E++K LG G+F +V + +H TK+ A+K++DK+K++KL V+ E +++ ++ P Sbjct: 45 FERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPF 104 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 +V L S +++V+EYV GG ++ H+ G E +R Q+V A + H + Sbjct: 105 LVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDL 164 Query: 425 YHRDIKPDNLLVDEHGNLK 481 +RD+KP+NLL+D G LK Sbjct: 165 IYRDLKPENLLIDSQGYLK 183
>SAPK4_ORYSA (Q5N942) Serine/threonine-protein kinase SAPK4 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 4) Length = 360 Score = 103 bits (258), Expect = 2e-22 Identities = 51/134 (38%), Positives = 81/134 (60%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHP 241 +YE V+ +G GNF L R+ +T+E VA+K +++ I + + REI R LRHP Sbjct: 3 KYEAVRDIGSGNFGVARLMRNRETRELVAVKCIERGHRID----ENVYREIINHRSLRHP 58 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 NI++ +V+ + + +VME+ GG L+ I G EDE R FQQL+ +++CH Sbjct: 59 NIIRFKEVILTPTHLMIVMEFAAGGELFDRICDRGRFSEDEARYFFQQLICGVSYCHHMQ 118 Query: 422 VYHRDIKPDNLLVD 463 + HRD+K +N+L+D Sbjct: 119 ICHRDLKLENVLLD 132
>SAPK6_ORYSA (Q6ZI44) Serine/threonine-protein kinase SAPK6 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 6) Length = 365 Score = 103 bits (257), Expect = 2e-22 Identities = 53/134 (39%), Positives = 81/134 (60%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHP 241 +YE +K +G GNF L R+ +TKE VA+K + + I + + REI R LRHP Sbjct: 3 KYELLKDIGSGNFGVARLMRNRETKELVAMKYIPRGLKID----ENVAREIINHRSLRHP 58 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 NI++ +V+ + + +VMEY GG L+ I + G EDE+R FQQL+ +++CH Sbjct: 59 NIIRFKEVVLTPTHLAIVMEYAAGGELFDRICSAGRFSEDESRYFFQQLICGVSYCHFMQ 118 Query: 422 VYHRDIKPDNLLVD 463 + HRD+K +N L+D Sbjct: 119 ICHRDLKLENTLLD 132
>KPSH1_PINFU (Q4KTY1) Serine/threonine-protein kinase H1 homolog (EC 2.7.11.1)| Length = 415 Score = 103 bits (256), Expect = 3e-22 Identities = 50/143 (34%), Positives = 84/143 (58%) Frame = +2 Query: 47 PKLPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMR 226 P++ A+Y+ L+G GNF+KV H TK+ AIK++D+ + + + E+AV+R Sbjct: 74 PRVTAKYDIKALIGRGNFSKVVRVEHRVTKQPYAIKMIDRVQ-----GKEVFESEVAVLR 128 Query: 227 RLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTF 406 R++H I+QL +V K ++++VME GG L+ I A G E + R+ ++ + + Sbjct: 129 RVKHSYIIQLIEVFETKDKVYMVMELATGGELFDRIIAKGSFTERDATRVLNMVLDGVKY 188 Query: 407 CHAQGVYHRDIKPDNLLVDEHGN 475 H G+ HRD+KP+NLL G+ Sbjct: 189 LHGLGITHRDLKPENLLYYHPGH 211
>SAPK7_ORYSA (Q7XQP4) Serine/threonine-protein kinase SAPK7 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 7) Length = 359 Score = 103 bits (256), Expect = 3e-22 Identities = 54/134 (40%), Positives = 79/134 (58%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHP 241 RYE +K +G GNF L R+ +TKE VA+K + + I + + REI R LRHP Sbjct: 3 RYELLKDIGAGNFGVARLMRNKETKELVAMKYIPRGLKID----ENVAREIINHRSLRHP 58 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 NI++ +V+ + + +VMEY GG L+ I G EDE R FQQL+ +++CH Sbjct: 59 NIIRFKEVVVTPTHLAIVMEYAAGGELFDRICNAGRFSEDEARYFFQQLICGVSYCHFMQ 118 Query: 422 VYHRDIKPDNLLVD 463 + HRD+K +N L+D Sbjct: 119 ICHRDLKLENTLLD 132
>ST32A_MOUSE (Q8BGW6) Serine/threonine-protein kinase 32A (EC 2.7.11.1)| Length = 398 Score = 102 bits (255), Expect = 4e-22 Identities = 48/138 (34%), Positives = 86/138 (62%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 +E ++ +G+G+F KV + R DTK+ A+K M+K+K ++ V+ + +E+ +M+ L HP Sbjct: 23 FEILRAIGKGSFGKVCIVRKNDTKKMYAMKYMNKQKCVERNEVRNVFKELQIMQGLEHPF 82 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 +V L + +F+V++ + GG L H+ N +ED + +L AL + +Q + Sbjct: 83 LVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFQEDTVKLFICELAMALDYLQSQRI 142 Query: 425 YHRDIKPDNLLVDEHGNL 478 HRD+KPDN+L+DEHG++ Sbjct: 143 IHRDMKPDNILLDEHGHV 160
>KAPCG_MACMU (O62846) cAMP-dependent protein kinase, gamma-catalytic subunit (EC| 2.7.11.11) (PKA C-gamma) (Fragment) Length = 208 Score = 102 bits (255), Expect = 4e-22 Identities = 47/140 (33%), Positives = 85/140 (60%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHP 241 ++E++K LG G++ +V L RH +T A+K++DK+K+++L V+ E +++ + P Sbjct: 41 QFERLKTLGTGSYGRVMLVRHRETGNHYAMKILDKQKVVRLKQVEHTLNEKRILQAINFP 100 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 +V+L S +++VMEYV GG ++ H+ G E + Q+V A + H+ Sbjct: 101 FLVKLQFSFKDNSNLYLVMEYVPGGEMFSHLRRVGRFSEPQACFYAAQVVLAFQYLHSLD 160 Query: 422 VYHRDIKPDNLLVDEHGNLK 481 + HRD+KP+NLL+D+ G L+ Sbjct: 161 LIHRDLKPENLLIDQQGYLQ 180
>CHK1_XENLA (Q6DE87) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (xChk1| protein) Length = 474 Score = 102 bits (254), Expect = 5e-22 Identities = 52/139 (37%), Positives = 86/139 (61%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 ++ V+ LGEG + +V LA + T+E VA+K++D + + IK+EI + R L H N Sbjct: 9 WDLVQTLGEGAYGEVQLAVNRKTEEAVAVKIVDMTRAAD--CPENIKKEICINRMLSHTN 66 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 IV+ + + ++ +EY RGG L+ I + G+ E + ++ FQQL++ + + H+ G+ Sbjct: 67 IVRFYGHRREGNIQYLFLEYCRGGELFDRIEPDVGMPEQDAQKFFQQLIAGVEYLHSIGI 126 Query: 425 YHRDIKPDNLLVDEHGNLK 481 HRDIKP+NLL+DE LK Sbjct: 127 THRDIKPENLLLDERDQLK 145
>KPK1_ARATH (P42818) Serine/threonine-protein kinase AtPK1/AtPK6 (EC 2.7.11.1)| Length = 465 Score = 102 bits (254), Expect = 5e-22 Identities = 48/138 (34%), Positives = 87/138 (63%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 +E +K++G+G F KVY R +T E A+KVM K+ +++ + +K E ++ ++ HP Sbjct: 134 FEVMKVVGKGAFGKVYQVRKKETSEIYAMKVMRKDHIMEKNHAEYMKAERDILTKIDHPF 193 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 IVQL K R+++V++++ GG L+ + G +ED R ++VSA++ H +G+ Sbjct: 194 IVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHEKGI 253 Query: 425 YHRDIKPDNLLVDEHGNL 478 HRD+KP+N+L+D G++ Sbjct: 254 MHRDLKPENILMDTDGHV 271
>KAPCA_PIG (P36887) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 102 bits (254), Expect = 5e-22 Identities = 45/140 (32%), Positives = 84/140 (60%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHP 241 ++E++K LG G+F +V L +H +T A+K++DK+K++KL ++ E +++ + P Sbjct: 42 QFERIKTLGTGSFGRVMLVKHKETGNHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFP 101 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 +V+L S +++VMEYV GG ++ H+ G E R Q+V + H+ Sbjct: 102 FLVKLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLD 161 Query: 422 VYHRDIKPDNLLVDEHGNLK 481 + +RD+KP+NLL+D+ G ++ Sbjct: 162 LIYRDLKPENLLIDQQGYIQ 181
>KAPCA_CANFA (Q8MJ44) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 349 Score = 102 bits (253), Expect = 7e-22 Identities = 45/140 (32%), Positives = 84/140 (60%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHP 241 ++E++K LG G+F +V L +H +T A+K++DK+K++KL ++ E +++ + P Sbjct: 41 QFERIKTLGTGSFGRVMLVKHKETGNHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFP 100 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 +V+L S +++VMEYV GG ++ H+ G E R Q+V + H+ Sbjct: 101 FLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLD 160 Query: 422 VYHRDIKPDNLLVDEHGNLK 481 + +RD+KP+NLL+D+ G ++ Sbjct: 161 LIYRDLKPENLLIDQQGYIQ 180
>DCAK1_RAT (O08875) Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 1) (Calcium/calmodulin-dependent protein kinase type I-like CPG16) Length = 433 Score = 102 bits (253), Expect = 7e-22 Identities = 54/154 (35%), Positives = 85/154 (55%) Frame = +2 Query: 8 PAQESGDGAMGDRPKLPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLG 187 P +E D + RY+ + +G+GNFA V T E A+K++ K K G Sbjct: 64 PGEEESDEGFQIPATITERYKVGRTIGDGNFAVVKECIERSTAREYALKIIKKSKC--RG 121 Query: 188 AVQQIKREIAVMRRLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDET 367 I+ E++++RR++HPNIV L + M + +++VME V+GG L+ I + E + Sbjct: 122 KEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTSKYTERDA 181 Query: 368 RRIFQQLVSALTFCHAQGVYHRDIKPDNLLVDEH 469 + L SA+ + H+ + HRDIKP+NLLV EH Sbjct: 182 SGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEH 215
>PKN2_BACSU (O34507) Probable serine/threonine-protein kinase yloP (EC| 2.7.11.1) Length = 648 Score = 102 bits (253), Expect = 7e-22 Identities = 53/144 (36%), Positives = 81/144 (56%) Frame = +2 Query: 50 KLPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRR 229 ++ RY+ ++++G G A VYLA + EVAIK++ + +++ +RE Sbjct: 6 RISGRYQILRVIGGGGMANVYLAEDIILDREVAIKILRFDYANDNEFIRRFRREAQSASS 65 Query: 230 LRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFC 409 L HPNIV ++ + ++VMEYV G L +I ANG L E I +Q+VSA+ Sbjct: 66 LDHPNIVSIYDLGEEDDIYYIVMEYVEGMTLKEYITANGPLHPKEALNIMEQIVSAIAHA 125 Query: 410 HAQGVYHRDIKPDNLLVDEHGNLK 481 H + HRDIKP N+L+D GN+K Sbjct: 126 HQNQIVHRDIKPHNILIDHMGNIK 149
>KAPCA_SHEEP (Q9MZD9) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 102 bits (253), Expect = 7e-22 Identities = 45/140 (32%), Positives = 84/140 (60%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHP 241 ++E++K LG G+F +V L +H +T A+K++DK+K++KL ++ E +++ + P Sbjct: 42 QFERIKTLGTGSFGRVMLVKHTETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFP 101 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 +V+L S +++VMEYV GG ++ H+ G E R Q+V + H+ Sbjct: 102 FLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLD 161 Query: 422 VYHRDIKPDNLLVDEHGNLK 481 + +RD+KP+NLL+D+ G ++ Sbjct: 162 LIYRDLKPENLLIDQQGYIQ 181
>KAPCA_HUMAN (P17612) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 102 bits (253), Expect = 7e-22 Identities = 45/140 (32%), Positives = 84/140 (60%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHP 241 ++E++K LG G+F +V L +H +T A+K++DK+K++KL ++ E +++ + P Sbjct: 42 QFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFP 101 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 +V+L S +++VMEYV GG ++ H+ G E R Q+V + H+ Sbjct: 102 FLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLD 161 Query: 422 VYHRDIKPDNLLVDEHGNLK 481 + +RD+KP+NLL+D+ G ++ Sbjct: 162 LIYRDLKPENLLIDQQGYIQ 181
>ST32A_HUMAN (Q8WU08) Serine/threonine-protein kinase 32A (EC 2.7.11.1) (YANK1)| Length = 396 Score = 101 bits (252), Expect = 9e-22 Identities = 48/138 (34%), Positives = 86/138 (62%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 +E ++ +G+G+F KV + + DTK+ A+K M+K+K ++ V+ + +E+ +M+ L HP Sbjct: 23 FEILRAIGKGSFGKVCIVQKNDTKKMYAMKYMNKQKCVERNEVRNVFKELQIMQGLEHPF 82 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 +V L + +F+V++ + GG L H+ N KE+ + +LV AL + Q + Sbjct: 83 LVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFKEETVKLFICELVMALDYLQNQRI 142 Query: 425 YHRDIKPDNLLVDEHGNL 478 HRD+KPDN+L+DEHG++ Sbjct: 143 IHRDMKPDNILLDEHGHV 160
>SAPKA_ORYSA (Q75H77) Serine/threonine-protein kinase SAPK10 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 10) Length = 362 Score = 101 bits (252), Expect = 9e-22 Identities = 53/134 (39%), Positives = 79/134 (58%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHP 241 RYE V+ +G GNF L R + VA+K +++ I + ++REI R LRHP Sbjct: 22 RYELVRDIGSGNFGVARLMRSRADGQLVAVKYIERGDKID----ENVQREIINHRSLRHP 77 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 NI++ +V+ + + +VMEY GG L+ I G EDE R FQQL+S +++CH+ Sbjct: 78 NIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLISGVSYCHSMQ 137 Query: 422 VYHRDIKPDNLLVD 463 V HRD+K +N L+D Sbjct: 138 VCHRDLKLENTLLD 151
>GIN4_YEAST (Q12263) Serine/threonine-protein kinase GIN4 (EC 2.7.11.1)| Length = 1142 Score = 101 bits (251), Expect = 1e-21 Identities = 54/148 (36%), Positives = 85/148 (57%), Gaps = 15/148 (10%) Frame = +2 Query: 83 LGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQ---------------IKREIA 217 LG G+ KV LAR+ T +E A+KV+ K + G V I+REI Sbjct: 25 LGLGSTGKVQLARNGSTGQEAAVKVISKA-VFNTGNVSGTSIVGSTTPDALPYGIEREII 83 Query: 218 VMRRLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSA 397 +M+ L HPN+++L+ V + +++V+EY G L+ + G L E E R F+Q++ Sbjct: 84 IMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAIRFFRQIIIG 143 Query: 398 LTFCHAQGVYHRDIKPDNLLVDEHGNLK 481 +++CHA G+ HRD+KP+NLL+D N+K Sbjct: 144 VSYCHALGIVHRDLKPENLLLDHKYNIK 171
>IPL1_YEAST (P38991) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) (Increase-in-ploidy protein 1) Length = 367 Score = 101 bits (251), Expect = 1e-21 Identities = 47/139 (33%), Positives = 81/139 (58%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 +E K LG+G F KVY RH T A+KVM+KE++IK +Q +RE+ + L HPN Sbjct: 104 FELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKYNLQKQFRREVEIQTSLNHPN 163 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 + + + + R++++MEY+ G +Y+ + +G + Q+ +AL + H + + Sbjct: 164 LTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALDYMHKKNI 223 Query: 425 YHRDIKPDNLLVDEHGNLK 481 HRDIKP+N+L+ + +K Sbjct: 224 IHRDIKPENILIGFNNVIK 242
>CHK1_RAT (Q91ZN7) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 101 bits (251), Expect = 1e-21 Identities = 51/139 (36%), Positives = 86/139 (61%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 ++ V+ LGEG + +V LA + T+E VA+K++D ++ I + IK+EI + + L H N Sbjct: 9 WDLVQTLGEGAYGEVQLAVNRITEEAVAVKIVDMKRAID--CPENIKKEICINKMLNHEN 66 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 +V+ + + ++ +EY GG L+ I + G+ E + +R F QL++ + + H G+ Sbjct: 67 VVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEQDAQRFFHQLMAGVVYLHGIGI 126 Query: 425 YHRDIKPDNLLVDEHGNLK 481 HRDIKP+NLL+DE NLK Sbjct: 127 THRDIKPENLLLDERDNLK 145
>SAPK1_ORYSA (Q75LR7) Serine/threonine-protein kinase SAPK1 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 1) Length = 342 Score = 100 bits (249), Expect = 2e-21 Identities = 51/134 (38%), Positives = 79/134 (58%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHP 241 RYE ++ +G GNF L R + T A+K +++ I + ++REI R L+HP Sbjct: 3 RYEVMRDIGSGNFGVAKLVRDVATNHLFAVKFIERGLKID----EHVQREIMNHRSLKHP 58 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 NI++ +V+ + + +VMEY GG L+ I G EDE R FQQL+S +++CH+ Sbjct: 59 NIIRFKEVVLTPTHLAIVMEYAAGGELFERICNAGRFSEDEARFFFQQLISGVSYCHSMQ 118 Query: 422 VYHRDIKPDNLLVD 463 V HRD+K +N L+D Sbjct: 119 VCHRDLKLENTLLD 132
>CHK1_HUMAN (O14757) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 100 bits (249), Expect = 2e-21 Identities = 50/139 (35%), Positives = 86/139 (61%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 ++ V+ LGEG + +V LA + T+E VA+K++D ++ + + IK+EI + + L H N Sbjct: 9 WDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVD--CPENIKKEICINKMLNHEN 66 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 +V+ + + ++ +EY GG L+ I + G+ E + +R F QL++ + + H G+ Sbjct: 67 VVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGI 126 Query: 425 YHRDIKPDNLLVDEHGNLK 481 HRDIKP+NLL+DE NLK Sbjct: 127 THRDIKPENLLLDERDNLK 145
>KAPCA_CRIGR (P25321) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 100 bits (249), Expect = 2e-21 Identities = 44/139 (31%), Positives = 83/139 (59%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 ++++K LG G+F +V L +H +T A+K++DK+K++KL ++ E +++ + P Sbjct: 43 FDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 102 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 +V+L S +++VMEYV GG ++ H+ G E R Q+V + H+ + Sbjct: 103 LVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 162 Query: 425 YHRDIKPDNLLVDEHGNLK 481 +RD+KP+NLL+D+ G ++ Sbjct: 163 IYRDLKPENLLIDQQGYIQ 181
>AKT1_DROME (Q8INB9) RAC serine/threonine-protein kinase (EC 2.7.11.1)| (DRAC-PK) (Akt) (Dakt1) (Protein kinase B) (PKB) Length = 611 Score = 100 bits (248), Expect = 3e-21 Identities = 51/139 (36%), Positives = 81/139 (58%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 +E +K+LG+G F KV L R T + AIK++ KE +I+ V E V++ HP Sbjct: 266 FEFLKVLGKGTFGKVILCREKATAKLYAIKILKKEVIIQKDEVAHTLTESRVLKSTNHPF 325 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 ++ L R+ VM+YV GG L+ H+ ED TR +++SAL + H+QG+ Sbjct: 326 LISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGAEIISALGYLHSQGI 385 Query: 425 YHRDIKPDNLLVDEHGNLK 481 +RD+K +NLL+D+ G++K Sbjct: 386 IYRDLKLENLLLDKDGHIK 404
>KPSH1_MOUSE (Q91YA2) Serine/threonine-protein kinase H1 (EC 2.7.11.1) (PSK-H1)| Length = 423 Score = 100 bits (248), Expect = 3e-21 Identities = 49/137 (35%), Positives = 85/137 (62%) Frame = +2 Query: 47 PKLPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMR 226 P++ A+Y+ L+G G+F++V H T++ AIK+++ + + G + + E+ V+R Sbjct: 91 PRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETK--YREGR-EVCESELRVLR 147 Query: 227 RLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTF 406 R+RH NI+QL +V + R+++VME GG L+ I A G E + R+ Q ++ + + Sbjct: 148 RVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRY 207 Query: 407 CHAQGVYHRDIKPDNLL 457 HA G+ HRD+KP+NLL Sbjct: 208 LHALGITHRDLKPENLL 224
>KPSH1_HUMAN (P11801) Serine/threonine-protein kinase H1 (EC 2.7.11.1) (PSK-H1)| Length = 423 Score = 100 bits (248), Expect = 3e-21 Identities = 49/137 (35%), Positives = 85/137 (62%) Frame = +2 Query: 47 PKLPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMR 226 P++ A+Y+ L+G G+F++V H T++ AIK+++ + + G + + E+ V+R Sbjct: 91 PRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETK--YREGR-EVCESELRVLR 147 Query: 227 RLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTF 406 R+RH NI+QL +V + R+++VME GG L+ I A G E + R+ Q ++ + + Sbjct: 148 RVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRY 207 Query: 407 CHAQGVYHRDIKPDNLL 457 HA G+ HRD+KP+NLL Sbjct: 208 LHALGITHRDLKPENLL 224
>CHK1_MOUSE (O35280) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 100 bits (248), Expect = 3e-21 Identities = 51/139 (36%), Positives = 85/139 (61%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 ++ V+ LGEG + +V LA + T+E VA+K++D ++ I + IK+EI + + L H N Sbjct: 9 WDLVQTLGEGAYGEVQLAVNRITEEAVAVKIVDMKRAID--CPENIKKEICINKMLSHEN 66 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 +V+ + ++ +EY GG L+ I + G+ E + +R F QL++ + + H G+ Sbjct: 67 VVKFYGHRREGHIQYLFLEYCSGGELFDRIEPDIGMPEQDAQRFFHQLMAGVVYLHGIGI 126 Query: 425 YHRDIKPDNLLVDEHGNLK 481 HRDIKP+NLL+DE NLK Sbjct: 127 THRDIKPENLLLDERDNLK 145
>ARK1_SCHPO (O59790) Serine/threonine-protein kinase ark1 (EC 2.7.11.1)| (Aurora-related kinase 1) Length = 355 Score = 99.8 bits (247), Expect = 3e-21 Identities = 49/139 (35%), Positives = 84/139 (60%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 +E K LG+G F +VYLA+ T VA+K + K +L++ +Q++REI + LRH N Sbjct: 89 FEIGKPLGKGKFGRVYLAKEKKTGFIVALKTLHKSELVQSKIEKQVRREIEIQSNLRHKN 148 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 I++L+ + RI++++E+ G LY+H+ E+ + Q+ +AL++ H + V Sbjct: 149 ILRLYGHFHDEKRIYLILEFAGRGELYQHLRRAKRFSEEVASKYIFQMANALSYLHKKHV 208 Query: 425 YHRDIKPDNLLVDEHGNLK 481 HRDIKP+N+L+ G +K Sbjct: 209 IHRDIKPENILLGIDGEIK 227
>KAPB2_BOVIN (P24256) cAMP-dependent protein kinase, beta-2-catalytic subunit| (EC 2.7.11.11) (PKA C-beta-2) Length = 397 Score = 99.8 bits (247), Expect = 3e-21 Identities = 45/139 (32%), Positives = 82/139 (58%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 +E+ K LG G+F +V L +H T++ A+K++DK+K++KL ++ E +++ + P Sbjct: 90 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 149 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 +V+L S +++VMEYV GG ++ H+ G E R Q+V + H+ + Sbjct: 150 LVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 209 Query: 425 YHRDIKPDNLLVDEHGNLK 481 +RD+KP+NLL+D G ++ Sbjct: 210 IYRDLKPENLLIDHQGYIQ 228
>DCAK1_HUMAN (O15075) Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 1) Length = 740 Score = 99.8 bits (247), Expect = 3e-21 Identities = 53/154 (34%), Positives = 85/154 (55%) Frame = +2 Query: 8 PAQESGDGAMGDRPKLPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLG 187 P +E + + RY+ + +G+GNFA V T E A+K++ K K G Sbjct: 371 PGEEVSEEGFQIPATITERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKC--RG 428 Query: 188 AVQQIKREIAVMRRLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDET 367 I+ E++++RR++HPNIV L + M + +++VME V+GG L+ I + E + Sbjct: 429 KEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDA 488 Query: 368 RRIFQQLVSALTFCHAQGVYHRDIKPDNLLVDEH 469 + L SA+ + H+ + HRDIKP+NLLV EH Sbjct: 489 SGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEH 522
>KIN4_YEAST (Q01919) Serine/threonine-protein kinase KIN4 (EC 2.7.11.1)| Length = 800 Score = 99.8 bits (247), Expect = 3e-21 Identities = 56/139 (40%), Positives = 86/139 (61%), Gaps = 7/139 (5%) Frame = +2 Query: 83 LGEGNFAKVYL-----ARHMDTKEEVAIKVMDKEKLIKLGAVQQIK--REIAVMRRLRHP 241 LGEG F KV L + + ++VAIK++ ++ IK A ++IK REI ++ L HP Sbjct: 52 LGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDT-IKKDADKEIKIYREINALKHLTHP 110 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 NI+ L +V+ I +V+E+V GG Y++I LKE R+F QL+S + + H +G Sbjct: 111 NIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKRRLKESSACRLFAQLISGVNYMHYKG 170 Query: 422 VYHRDIKPDNLLVDEHGNL 478 + HRD+K +NLL+D+H NL Sbjct: 171 LVHRDLKLENLLLDKHENL 189
>KCC4_YEAST (P25389) Probable serine/threonine-protein kinase KCC4 (EC| 2.7.11.1) Length = 1037 Score = 99.8 bits (247), Expect = 3e-21 Identities = 50/141 (35%), Positives = 80/141 (56%), Gaps = 8/141 (5%) Frame = +2 Query: 83 LGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLG--------AVQQIKREIAVMRRLRH 238 LG G+ KV LA+H T A+KV+ K G I+REI +M+ L H Sbjct: 27 LGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSH 86 Query: 239 PNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQ 418 PN++ L+ V + +++++EY G L+ + +G L E E F+Q++ +++CHA Sbjct: 87 PNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHAL 146 Query: 419 GVYHRDIKPDNLLVDEHGNLK 481 G+ HRD+KP+NLL+D N+K Sbjct: 147 GIVHRDLKPENLLLDSFYNIK 167
>KAPCB_HUMAN (P22694) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 99.8 bits (247), Expect = 3e-21 Identities = 45/139 (32%), Positives = 82/139 (58%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 +E+ K LG G+F +V L +H T++ A+K++DK+K++KL ++ E +++ + P Sbjct: 43 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 102 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 +V+L S +++VMEYV GG ++ H+ G E R Q+V + H+ + Sbjct: 103 LVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 162 Query: 425 YHRDIKPDNLLVDEHGNLK 481 +RD+KP+NLL+D G ++ Sbjct: 163 IYRDLKPENLLIDHQGYIQ 181
>KAPCA_MOUSE (P05132) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 99.8 bits (247), Expect = 3e-21 Identities = 43/140 (30%), Positives = 84/140 (60%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHP 241 +++++K LG G+F +V L +H ++ A+K++DK+K++KL ++ E +++ + P Sbjct: 42 QFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFP 101 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 +V+L S +++VMEYV GG ++ H+ G E R Q+V + H+ Sbjct: 102 FLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLD 161 Query: 422 VYHRDIKPDNLLVDEHGNLK 481 + +RD+KP+NLL+D+ G ++ Sbjct: 162 LIYRDLKPENLLIDQQGYIQ 181
>KAPB1_BOVIN (P05131) cAMP-dependent protein kinase, beta-1-catalytic subunit| (EC 2.7.11.11) (PKA C-beta-1) Length = 350 Score = 99.8 bits (247), Expect = 3e-21 Identities = 45/139 (32%), Positives = 82/139 (58%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 +E+ K LG G+F +V L +H T++ A+K++DK+K++KL ++ E +++ + P Sbjct: 43 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 102 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 +V+L S +++VMEYV GG ++ H+ G E R Q+V + H+ + Sbjct: 103 LVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 162 Query: 425 YHRDIKPDNLLVDEHGNLK 481 +RD+KP+NLL+D G ++ Sbjct: 163 IYRDLKPENLLIDHQGYIQ 181
>DCAK2_HUMAN (Q8N568) Serine/threonine-protein kinase DCAMKL2 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 2) Length = 766 Score = 99.4 bits (246), Expect = 4e-21 Identities = 56/154 (36%), Positives = 90/154 (58%), Gaps = 4/154 (2%) Frame = +2 Query: 20 SGDGAMGDR----PKLPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLG 187 S +G G+R L +Y+ K++G+GNFA V T +E A+K++DK K G Sbjct: 375 SPEGVNGNRCSESSTLLEKYKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCC--G 432 Query: 188 AVQQIKREIAVMRRLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDET 367 I+ E++++RR++HPNI+ L + M + +F+VME V+GG L+ I ++ E + Sbjct: 433 KEHLIENEVSILRRVKHPNIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDG 492 Query: 368 RRIFQQLVSALTFCHAQGVYHRDIKPDNLLVDEH 469 + L +AL + H + HRDIKP+NLLV E+ Sbjct: 493 SAMVYNLANALRYLHGLSIVHRDIKPENLLVCEY 526
>AAIP_WHEAT (Q02066) Abscisic acid-inducible protein kinase (EC 2.7.11.1)| (Fragment) Length = 332 Score = 99.4 bits (246), Expect = 4e-21 Identities = 50/126 (39%), Positives = 76/126 (60%) Frame = +2 Query: 86 GEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPNIVQLHKV 265 G GNF L R + TKE A+K +++ I + ++REI R L+HPNI++ +V Sbjct: 1 GSGNFGVAKLVRDVRTKEHFAVKFIERGHKID----EHVQREIMNHRSLKHPNIIRFKEV 56 Query: 266 MACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGVYHRDIKP 445 + + + +VMEY GG L++ I G EDE R FQQL+S +++CH+ V HRD+K Sbjct: 57 VLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFFQQLISGVSYCHSMQVCHRDLKL 116 Query: 446 DNLLVD 463 +N L+D Sbjct: 117 ENTLLD 122
>MAST3_HUMAN (O60307) Microtubule-associated serine/threonine-protein kinase 3| (EC 2.7.11.1) Length = 1309 Score = 99.0 bits (245), Expect = 6e-21 Identities = 56/162 (34%), Positives = 86/162 (53%), Gaps = 4/162 (2%) Frame = +2 Query: 8 PAQESGDGA--MGDRPKLPAR--YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKL 175 PA ES + +G + P +E +KL+ G + VYL RH DT++ AIK ++K+ L Sbjct: 344 PAPESPESRALVGQSRRKPCESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNL 403 Query: 176 IKLGAVQQIKREIAVMRRLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLK 355 I +QQ+ E ++ +P +V + + + +VMEYV GG + G L Sbjct: 404 ILRNQIQQVFVERDILTFAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLP 463 Query: 356 EDETRRIFQQLVSALTFCHAQGVYHRDIKPDNLLVDEHGNLK 481 D R F + V AL + H G+ HRD+KPDNLL+ G++K Sbjct: 464 VDMARLYFAETVLALEYLHNYGIVHRDLKPDNLLITSLGHIK 505
>KAPCB_RAT (P68182) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 99.0 bits (245), Expect = 6e-21 Identities = 45/139 (32%), Positives = 82/139 (58%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 +E+ K LG G+F +V L +H T++ A+K++DK+K++KL ++ E +++ + P Sbjct: 43 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPF 102 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 +V+L S +++VMEYV GG ++ H+ G E R Q+V + H+ + Sbjct: 103 LVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 162 Query: 425 YHRDIKPDNLLVDEHGNLK 481 +RD+KP+NLL+D G ++ Sbjct: 163 IYRDLKPENLLIDHQGYIQ 181
>KAPCB_MOUSE (P68181) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 99.0 bits (245), Expect = 6e-21 Identities = 45/139 (32%), Positives = 82/139 (58%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 +E+ K LG G+F +V L +H T++ A+K++DK+K++KL ++ E +++ + P Sbjct: 43 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPF 102 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 +V+L S +++VMEYV GG ++ H+ G E R Q+V + H+ + Sbjct: 103 LVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 162 Query: 425 YHRDIKPDNLLVDEHGNLK 481 +RD+KP+NLL+D G ++ Sbjct: 163 IYRDLKPENLLIDHQGYIQ 181
>KAPCB_CRIGR (P68180) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 99.0 bits (245), Expect = 6e-21 Identities = 45/139 (32%), Positives = 82/139 (58%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 +E+ K LG G+F +V L +H T++ A+K++DK+K++KL ++ E +++ + P Sbjct: 43 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPF 102 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 +V+L S +++VMEYV GG ++ H+ G E R Q+V + H+ + Sbjct: 103 LVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 162 Query: 425 YHRDIKPDNLLVDEHGNLK 481 +RD+KP+NLL+D G ++ Sbjct: 163 IYRDLKPENLLIDHQGYIQ 181
>KAPCA_RAT (P27791) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 99.0 bits (245), Expect = 6e-21 Identities = 43/139 (30%), Positives = 83/139 (59%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 ++++K LG G+F +V L +H ++ A+K++DK+K++KL ++ E +++ + P Sbjct: 43 FDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 102 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 +V+L S +++VMEYV GG ++ H+ G E R Q+V + H+ + Sbjct: 103 LVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 162 Query: 425 YHRDIKPDNLLVDEHGNLK 481 +RD+KP+NLL+D+ G ++ Sbjct: 163 IYRDLKPENLLIDQQGYIQ 181
>DCAK1_MOUSE (Q9JLM8) Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 1) Length = 756 Score = 98.6 bits (244), Expect = 8e-21 Identities = 51/136 (37%), Positives = 80/136 (58%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHP 241 RY+ + +G+GNFA V T E A+K++ K K G I+ E++++RR++HP Sbjct: 405 RYKVGRTIGDGNFAVVKECIERSTAREYALKIIKKSKC--RGKEHMIQNEVSILRRVKHP 462 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 NIV L + M + +++VME V+GG L+ I + E + + L SA+ + H+ Sbjct: 463 NIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTSKYTERDASGMLYNLASAIKYLHSLN 522 Query: 422 VYHRDIKPDNLLVDEH 469 + HRDIKP+NLLV EH Sbjct: 523 IVHRDIKPENLLVYEH 538
>KAPCB_PIG (P05383) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 98.6 bits (244), Expect = 8e-21 Identities = 45/139 (32%), Positives = 82/139 (58%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 +E+ K LG G+F +V L +H T++ A+K++DK+K++KL ++ E +++ + P Sbjct: 43 FERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 102 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 +V+L S +++VMEYV GG ++ H+ G E R Q+V + H+ + Sbjct: 103 LVRLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 162 Query: 425 YHRDIKPDNLLVDEHGNLK 481 +RD+KP+NLL+D G ++ Sbjct: 163 IYRDLKPENLLIDHQGYIQ 181
>KPSH1_BRARE (Q501V0) Serine/threonine-protein kinase H1 homolog (EC 2.7.11.1)| Length = 422 Score = 97.8 bits (242), Expect = 1e-20 Identities = 48/137 (35%), Positives = 81/137 (59%) Frame = +2 Query: 47 PKLPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMR 226 P++ A+Y+ L+G G+F++V H T++ AIK++ E + G + + E+ V+R Sbjct: 90 PRVTAKYDIKALIGRGSFSRVVRVEHRSTRQPYAIKMI--ETRYREGR-EVCESELCVLR 146 Query: 227 RLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTF 406 R+RH NI+QL +V R+++VME GG L+ I G E + R+ Q ++ + + Sbjct: 147 RVRHTNIIQLMEVFETAERVYMVMELATGGELFDRIITRGSFTERDATRVLQMVLDGVKY 206 Query: 407 CHAQGVYHRDIKPDNLL 457 H G+ HRD+KP+NLL Sbjct: 207 LHTLGITHRDLKPENLL 223
>ULK2_HUMAN (Q8IYT8) Serine/threonine-protein kinase ULK2 (EC 2.7.11.1)| (Unc-51-like kinase 2) Length = 1036 Score = 97.8 bits (242), Expect = 1e-20 Identities = 52/133 (39%), Positives = 80/133 (60%), Gaps = 1/133 (0%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMD-TKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHP 241 Y + L+G G FA V+ RH T EVAIK ++K+ L K + + +EI +++ L+H Sbjct: 9 YSKRDLVGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQIL--LGKEIKILKELQHE 66 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 NIV L+ V + +F+VMEY GG L ++ A G L ED R Q+ +A+ H++G Sbjct: 67 NIVALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMRILHSKG 126 Query: 422 VYHRDIKPDNLLV 460 + HRD+KP N+L+ Sbjct: 127 IIHRDLKPQNILL 139
>KAPCG_HUMAN (P22612) cAMP-dependent protein kinase, gamma-catalytic subunit (EC| 2.7.11.11) (PKA C-gamma) Length = 350 Score = 97.8 bits (242), Expect = 1e-20 Identities = 46/140 (32%), Positives = 85/140 (60%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHP 241 ++E+++ LG G+F +V L RH +T A+K+++K+K++K+ V+ I E +++ + P Sbjct: 42 QFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFP 101 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 +V+L S +++VMEYV GG ++ + G E Q+V A+ + H+ Sbjct: 102 FLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLD 161 Query: 422 VYHRDIKPDNLLVDEHGNLK 481 + HRD+KP+NLL+D+ G L+ Sbjct: 162 LIHRDLKPENLLIDQQGYLQ 181
>RAD53_YEAST (P22216) Serine/threonine-protein kinase RAD53 (EC 2.7.11.1)| (Serine-protein kinase 1) Length = 821 Score = 97.4 bits (241), Expect = 2e-20 Identities = 47/130 (36%), Positives = 82/130 (63%) Frame = +2 Query: 77 KLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPNIVQL 256 +++G+G FA V A T + A+K++ K K+I G + + RE+ V+++L HP IV+L Sbjct: 202 EVVGQGAFATVKKAIERTTGKTFAVKIISKRKVI--GNMDGVTRELEVLQKLNHPRIVRL 259 Query: 257 HKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGVYHRD 436 ++VME+V GG L + A+G + ED R I +Q+++A+ + H+ G+ HRD Sbjct: 260 KGFYEDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGREISRQILTAIKYIHSMGISHRD 319 Query: 437 IKPDNLLVDE 466 +KPDN+L+++ Sbjct: 320 LKPDNILIEQ 329
>MYLK_DICDI (P25323) Myosin light chain kinase (EC 2.7.11.18) (MLCK)| Length = 295 Score = 97.1 bits (240), Expect = 2e-20 Identities = 48/137 (35%), Positives = 82/137 (59%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 YE + LG G F+ VYL + TK+ AIKV++K +L K + +K E+ +++++ HPN Sbjct: 8 YEFKEELGRGAFSIVYLGENKQTKQRYAIKVINKSELGK-DYEKNLKMEVDILKKVNHPN 66 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 I+ L ++ ++++VME V GG L+ I G E + + +++VSA+ + H + Sbjct: 67 IIALKELFDTPEKLYLVMELVTGGELFDKIVEKGSYSEADAANLVKKIVSAVGYLHGLNI 126 Query: 425 YHRDIKPDNLLVDEHGN 475 HRD+KP+NLL+ N Sbjct: 127 VHRDLKPENLLLKSKEN 143
>AKT3_MOUSE (Q9WUA6) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) Length = 479 Score = 97.1 bits (240), Expect = 2e-20 Identities = 50/139 (35%), Positives = 79/139 (56%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 ++ +KLLG+G F KV L R + + A+K++ KE +I V E V++ RHP Sbjct: 148 FDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPF 207 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 + L K R+ VMEYV GG L+ H+ ED TR ++VSAL + H+ + Sbjct: 208 LTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKI 267 Query: 425 YHRDIKPDNLLVDEHGNLK 481 +RD+K +NL++D+ G++K Sbjct: 268 VYRDLKLENLMLDKDGHIK 286
>AKT3_HUMAN (Q9Y243) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) (STK-2) Length = 479 Score = 97.1 bits (240), Expect = 2e-20 Identities = 50/139 (35%), Positives = 79/139 (56%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 ++ +KLLG+G F KV L R + + A+K++ KE +I V E V++ RHP Sbjct: 148 FDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPF 207 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 + L K R+ VMEYV GG L+ H+ ED TR ++VSAL + H+ + Sbjct: 208 LTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKI 267 Query: 425 YHRDIKPDNLLVDEHGNLK 481 +RD+K +NL++D+ G++K Sbjct: 268 VYRDLKLENLMLDKDGHIK 286
>AKT3_RAT (Q63484) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) Length = 454 Score = 97.1 bits (240), Expect = 2e-20 Identities = 50/139 (35%), Positives = 79/139 (56%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 ++ +KLLG+G F KV L R + + A+K++ KE +I V E V++ RHP Sbjct: 148 FDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPF 207 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 + L K R+ VMEYV GG L+ H+ ED TR ++VSAL + H+ + Sbjct: 208 LTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKI 267 Query: 425 YHRDIKPDNLLVDEHGNLK 481 +RD+K +NL++D+ G++K Sbjct: 268 VYRDLKLENLMLDKDGHIK 286
>DCAK2_MOUSE (Q6PGN3) Serine/threonine-protein kinase DCAMKL2 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 2) Length = 756 Score = 97.1 bits (240), Expect = 2e-20 Identities = 56/154 (36%), Positives = 90/154 (58%), Gaps = 4/154 (2%) Frame = +2 Query: 20 SGDGAMGDRPK----LPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLG 187 S +G G+R L +Y K++G+GNFA V T +E A+K++DK K G Sbjct: 374 SPEGVNGNRCSESFPLLEKYRIGKVIGDGNFAVVKECVDRYTGKEFALKIIDKAKCC--G 431 Query: 188 AVQQIKREIAVMRRLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDET 367 I+ E++++RR++HPNI+ L + M + +F+VME V+GG L+ I ++ E + Sbjct: 432 KEHLIENEVSILRRVKHPNIIMLVEEMETATDLFLVMELVKGGDLFDAITSSTKYTERDG 491 Query: 368 RRIFQQLVSALTFCHAQGVYHRDIKPDNLLVDEH 469 + L +AL + H+ + HRDIKP+NLLV E+ Sbjct: 492 SAMVYNLANALRYLHSLSIVHRDIKPENLLVCEY 525
>KRAC_DICDI (P54644) RAC-family serine/threonine-protein kinase homolog (EC| 2.7.11.1) Length = 444 Score = 96.7 bits (239), Expect = 3e-20 Identities = 45/140 (32%), Positives = 82/140 (58%) Frame = +2 Query: 59 ARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRH 238 A +E + L+G+G+F KV R DT E A+KV+ K+ +++ V+ E +++++ H Sbjct: 118 ADFELLNLVGKGSFGKVIQVRKKDTGEVYAMKVLSKKHIVEHNEVEHTLSERNILQKINH 177 Query: 239 PNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQ 418 P +V L+ + +++ +++YV GG L+ H+ + ED R ++V AL H Sbjct: 178 PFLVNLNYSFQTEDKLYFILDYVNGGELFYHLQKDKKFTEDRVRYYGAEIVLALEHLHLS 237 Query: 419 GVYHRDIKPDNLLVDEHGNL 478 GV +RD+KP+NLL+ G++ Sbjct: 238 GVIYRDLKPENLLLTNEGHI 257
>ULK2_MOUSE (Q9QY01) Serine/threonine-protein kinase ULK2 (EC 2.7.11.1)| (Unc-51-like kinase 2) (Serine/threonine-protein kinase Unc51.2) Length = 1037 Score = 96.3 bits (238), Expect = 4e-20 Identities = 51/128 (39%), Positives = 78/128 (60%), Gaps = 1/128 (0%) Frame = +2 Query: 80 LLGEGNFAKVYLARHMD-TKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPNIVQL 256 L+G G FA V+ RH T EVAIK ++K+ L K + + +EI +++ L+H NIV L Sbjct: 14 LVGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQIL--LGKEIKILKELQHENIVAL 71 Query: 257 HKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGVYHRD 436 + V + +F+VMEY GG L ++ A G L ED R Q+ +A+ H++G+ HRD Sbjct: 72 YDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMRILHSKGIIHRD 131 Query: 437 IKPDNLLV 460 +KP N+L+ Sbjct: 132 LKPQNILL 139
>KAPC_DICDI (P34099) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) Length = 648 Score = 95.9 bits (237), Expect = 5e-20 Identities = 42/139 (30%), Positives = 83/139 (59%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 ++Q+++LG G F KVYL ++ A+K ++K +++L V+ + E +++ + HP Sbjct: 336 FKQIRVLGTGTFGKVYLIQNTKDGCYYAMKCLNKAYVVQLKQVEHLNSEKSILSSIHHPF 395 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 IV L++ + +++++ EYV GG ++ H+ + + ++V AL F H Q + Sbjct: 396 IVNLYQAFQDEKKLYLLFEYVAGGEVFTHLRKSMKFSNSTAKFYAAEIVLALEFLHKQNI 455 Query: 425 YHRDIKPDNLLVDEHGNLK 481 +RD+KP+NLL+D G++K Sbjct: 456 VYRDLKPENLLIDNQGHIK 474
>PLK4_HUMAN (O00444) Serine/threonine-protein kinase PLK4 (EC 2.7.11.21)| (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine-protein kinase 18) Length = 970 Score = 95.5 bits (236), Expect = 6e-20 Identities = 45/135 (33%), Positives = 83/135 (61%), Gaps = 1/135 (0%) Frame = +2 Query: 80 LLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPNIVQLH 259 LLG+G+FA VY A + T EVAIK++DK+ + K G VQ+++ E+ + +L+HP+I++L+ Sbjct: 17 LLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKHPSILELY 76 Query: 260 KVMACKSRIFVVMEYVRGGPLYRHIPAN-GGLKEDETRRIFQQLVSALTFCHAQGVYHRD 436 + +++V+E G + R++ E+E R Q+++ + + H+ G+ HRD Sbjct: 77 NYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHSHGILHRD 136 Query: 437 IKPDNLLVDEHGNLK 481 + NLL+ + N+K Sbjct: 137 LTLSNLLLTRNMNIK 151
>ST32B_HUMAN (Q9NY57) Serine/threonine-protein kinase 32B (EC 2.7.11.1) (YANK2)| Length = 414 Score = 95.5 bits (236), Expect = 6e-20 Identities = 47/138 (34%), Positives = 82/138 (59%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 ++ ++ +G+G+F KV + + DTK+ A+K M+K+K I+ V+ + RE+ +M+ L HP Sbjct: 23 FQILRAIGKGSFGKVCIVQKRDTKKMYAMKYMNKQKCIERDEVRNVFRELQIMQGLEHPF 82 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 +V L + +F+V++ + GG L H+ N E + +L AL + + Sbjct: 83 LVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFTEGTVKLYICELALALEYLQRYHI 142 Query: 425 YHRDIKPDNLLVDEHGNL 478 HRDIKPDN+L+DEHG++ Sbjct: 143 IHRDIKPDNILLDEHGHV 160
>SGK1_RAT (Q06226) Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 1) Length = 430 Score = 95.5 bits (236), Expect = 6e-20 Identities = 47/159 (29%), Positives = 90/159 (56%), Gaps = 1/159 (0%) Frame = +2 Query: 5 TPAQESGDGAMGDRPKLPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKL 184 +P+Q+ G + P+ + +K++G+G+F KV LARH + A+KV+ K+ ++K Sbjct: 78 SPSQQINLGPSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEAFYAVKVLQKKAILKK 137 Query: 185 GAVQQIKREIAVM-RRLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKED 361 + I E V+ + ++HP +V LH +++ V++Y+ GG L+ H+ E Sbjct: 138 KEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEP 197 Query: 362 ETRRIFQQLVSALTFCHAQGVYHRDIKPDNLLVDEHGNL 478 R ++ SAL + H+ + +RD+KP+N+L+D G++ Sbjct: 198 RARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHI 236
>KIN82_YEAST (P25341) Probable serine/threonine-protein kinase KIN82 (EC| 2.7.11.1) Length = 720 Score = 95.5 bits (236), Expect = 6e-20 Identities = 45/143 (31%), Positives = 85/143 (59%), Gaps = 2/143 (1%) Frame = +2 Query: 56 PARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLR 235 P +E+++LLG+G+ KVYL R DT + A+KV++K ++IK ++++ E ++ Sbjct: 321 PQSFEKIRLLGQGDVGKVYLMRERDTNQIFALKVLNKHEMIKRKKIKRVLTEQEILATSD 380 Query: 236 HPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGG--LKEDETRRIFQQLVSALTFC 409 HP IV L+ K +++ MEY GG +R + + E++ + ++V+AL + Sbjct: 381 HPFIVTLYHSFQTKDYLYLCMEYCMGGEFFRALQTRKSKCIAEEDAKFYASEVVAALEYL 440 Query: 410 HAQGVYHRDIKPDNLLVDEHGNL 478 H G +RD+KP+N+L+ + G++ Sbjct: 441 HLLGFIYRDLKPENILLHQSGHV 463
>SGK1_RABIT (Q9XT18) Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 1) Length = 431 Score = 95.5 bits (236), Expect = 6e-20 Identities = 47/159 (29%), Positives = 90/159 (56%), Gaps = 1/159 (0%) Frame = +2 Query: 5 TPAQESGDGAMGDRPKLPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKL 184 +P+Q+ G + P+ + +K++G+G+F KV LARH + A+KV+ K+ ++K Sbjct: 78 SPSQQINLGPSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEAFYAVKVLQKKAILKK 137 Query: 185 GAVQQIKREIAVM-RRLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKED 361 + I E V+ + ++HP +V LH +++ V++Y+ GG L+ H+ E Sbjct: 138 KEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEP 197 Query: 362 ETRRIFQQLVSALTFCHAQGVYHRDIKPDNLLVDEHGNL 478 R ++ SAL + H+ + +RD+KP+N+L+D G++ Sbjct: 198 RARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHI 236
>KAPC_CAEEL (P21137) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) (PKA C) Length = 404 Score = 95.5 bits (236), Expect = 6e-20 Identities = 43/139 (30%), Positives = 82/139 (58%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 ++++K LG G+F +V L +H + A+K++DK+K++KL V+ E +++ + P Sbjct: 81 FDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPF 140 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 +V + S +++V+E++ GG ++ H+ G E +R Q+V A + H+ + Sbjct: 141 LVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDL 200 Query: 425 YHRDIKPDNLLVDEHGNLK 481 +RD+KP+NLL+D G LK Sbjct: 201 IYRDLKPENLLIDSTGYLK 219
>TSSK1_MOUSE (Q61241) Testis-specific serine/threonine-protein kinase 1 (EC| 2.7.11.1) (TSSK-1) (Testis-specific kinase 1) (TSK-1) (Serine/threonine-protein kinase 22A) Length = 364 Score = 95.1 bits (235), Expect = 8e-20 Identities = 51/134 (38%), Positives = 81/134 (60%), Gaps = 1/134 (0%) Frame = +2 Query: 83 LGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPNIVQLHK 262 LGEG++AKV A K VA+K++D++K + + REI ++ L H +IV+ ++ Sbjct: 18 LGEGSYAKVKSAYSERLKFNVAVKIIDRKKAPSDFLEKFLPREIEILAMLNHRSIVKTYE 77 Query: 263 VMACKS-RIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGVYHRDI 439 + A ++++VME G L I G L+ED+ R+ F QL SA+ +CH V HRD+ Sbjct: 78 IFATSDGKVYIVMELGVQGDLLEFIKTRGALQEDDARKKFHQLSSAIKYCHDLDVVHRDL 137 Query: 440 KPDNLLVDEHGNLK 481 K +NLL+D+ N+K Sbjct: 138 KSENLLLDKDFNIK 151
>MAST2_HUMAN (Q6P0Q8) Microtubule-associated serine/threonine-protein kinase 2| (EC 2.7.11.1) Length = 1798 Score = 95.1 bits (235), Expect = 8e-20 Identities = 53/155 (34%), Positives = 81/155 (52%), Gaps = 2/155 (1%) Frame = +2 Query: 23 GDGAMGDRPKLPAR--YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQ 196 G GA K P+ +E +KL+ G + V+L RH T++ A+K ++K+ LI +Q Sbjct: 496 GHGASLPSKKTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQ 555 Query: 197 QIKREIAVMRRLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRI 376 Q E ++ +P +V + K + +VMEYV GG + G L D R Sbjct: 556 QAFVERDILTFAENPFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLY 615 Query: 377 FQQLVSALTFCHAQGVYHRDIKPDNLLVDEHGNLK 481 F + V AL + H G+ HRD+KPDNLL+ G++K Sbjct: 616 FAETVLALEYLHNYGIVHRDLKPDNLLITSMGHIK 650
>CHK1_DROME (O61661) Serine/threonine-protein kinase grp (EC 2.7.11.1) (Protein| grapes) (Chk1 homolog) Length = 512 Score = 95.1 bits (235), Expect = 8e-20 Identities = 51/155 (32%), Positives = 89/155 (57%) Frame = +2 Query: 17 ESGDGAMGDRPKLPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQ 196 E+G G R + + + LGEG + +V L + T E VA+K++D +K A Sbjct: 7 EAGTGPAATREFVEG-WTLAQTLGEGAYGEVKLLINRQTGEAVAMKMVDLKK--HPDAAN 63 Query: 197 QIKREIAVMRRLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRI 376 +++E+ + + L+ +I++ + S ++ +EY GG L+ I + G+ + E +R Sbjct: 64 SVRKEVCIQKMLQDKHILRFFGKRSQGSVEYIFLEYAAGGELFDRIEPDVGMPQHEAQRY 123 Query: 377 FQQLVSALTFCHAQGVYHRDIKPDNLLVDEHGNLK 481 F QL+S L + H +G+ HRD+KP+NLL+DEH N+K Sbjct: 124 FTQLLSGLNYLHQRGIAHRDLKPENLLLDEHDNVK 158
>ST32B_MOUSE (Q9JJX8) Serine/threonine-protein kinase 32B (EC 2.7.11.1)| Length = 414 Score = 95.1 bits (235), Expect = 8e-20 Identities = 46/138 (33%), Positives = 82/138 (59%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 ++ ++ +G+G+F KV + + DTK+ A+K M+K+K ++ V+ + RE+ +M+ L HP Sbjct: 23 FQILRAIGKGSFGKVCIVQKRDTKKMYAMKYMNKQKCVERDEVRNVFRELQIMQGLEHPF 82 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 +V L + +F+V++ + GG L H+ N E + +L AL + + Sbjct: 83 LVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFTEGTVKLYICELALALEYLQRYHI 142 Query: 425 YHRDIKPDNLLVDEHGNL 478 HRDIKPDN+L+DEHG++ Sbjct: 143 IHRDIKPDNILLDEHGHV 160
>SGK1_MOUSE (Q9WVC6) Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 1) Length = 431 Score = 95.1 bits (235), Expect = 8e-20 Identities = 47/159 (29%), Positives = 90/159 (56%), Gaps = 1/159 (0%) Frame = +2 Query: 5 TPAQESGDGAMGDRPKLPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKL 184 +P+Q+ G + P+ + +K++G+G+F KV LARH + A+KV+ K+ ++K Sbjct: 78 SPSQQINLGPSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKK 137 Query: 185 GAVQQIKREIAVM-RRLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKED 361 + I E V+ + ++HP +V LH +++ V++Y+ GG L+ H+ E Sbjct: 138 KEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEP 197 Query: 362 ETRRIFQQLVSALTFCHAQGVYHRDIKPDNLLVDEHGNL 478 R ++ SAL + H+ + +RD+KP+N+L+D G++ Sbjct: 198 RARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHI 236
>SGK1_HUMAN (O00141) Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 1) Length = 431 Score = 95.1 bits (235), Expect = 8e-20 Identities = 47/159 (29%), Positives = 90/159 (56%), Gaps = 1/159 (0%) Frame = +2 Query: 5 TPAQESGDGAMGDRPKLPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKL 184 +P+Q+ G + P+ + +K++G+G+F KV LARH + A+KV+ K+ ++K Sbjct: 78 SPSQQINLGPSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKK 137 Query: 185 GAVQQIKREIAVM-RRLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKED 361 + I E V+ + ++HP +V LH +++ V++Y+ GG L+ H+ E Sbjct: 138 KEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEP 197 Query: 362 ETRRIFQQLVSALTFCHAQGVYHRDIKPDNLLVDEHGNL 478 R ++ SAL + H+ + +RD+KP+N+L+D G++ Sbjct: 198 RARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHI 236
>MAST1_HUMAN (Q9Y2H9) Microtubule-associated serine/threonine-protein kinase 1| (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase) Length = 1570 Score = 95.1 bits (235), Expect = 8e-20 Identities = 52/162 (32%), Positives = 84/162 (51%), Gaps = 3/162 (1%) Frame = +2 Query: 5 TPAQES---GDGAMGDRPKLPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKL 175 TP Q+ G + +P ++ +KL+ G + VYL RH DT++ A+K ++K+ L Sbjct: 351 TPEQDDLSEGRSSKAKKPPGENDFDTIKLISNGAYGAVYLVRHRDTRQRFAMKKINKQNL 410 Query: 176 IKLGAVQQIKREIAVMRRLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLK 355 I +QQ E ++ +P +V + + + +VMEYV GG + G L Sbjct: 411 ILRNQIQQAFVERDILTFAENPFVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNIGALP 470 Query: 356 EDETRRIFQQLVSALTFCHAQGVYHRDIKPDNLLVDEHGNLK 481 + R F + V AL + H G+ HRD+KPDNLL+ G++K Sbjct: 471 VEMARMYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHIK 512
>KS6A_CAEEL (Q21734) Putative ribosomal protein S6 kinase alpha (EC 2.7.11.1)| Length = 784 Score = 94.7 bits (234), Expect = 1e-19 Identities = 47/145 (32%), Positives = 88/145 (60%), Gaps = 3/145 (2%) Frame = +2 Query: 56 PARYEQVKLLGEGNFAKVYLARHM---DTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMR 226 P ++E +K+LG+G+F KV+L R + D+ A+KV+ K L K+ Q+ K E ++ Sbjct: 101 PRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATL-KVRDRQRTKLERNILA 159 Query: 227 RLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTF 406 + HP IV+LH + +++++++++RGG L+ + ED+ + +L AL Sbjct: 160 HISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYLAELTLALEH 219 Query: 407 CHAQGVYHRDIKPDNLLVDEHGNLK 481 H+ G+ +RD+KP+N+L+D G++K Sbjct: 220 LHSLGIVYRDLKPENILLDADGHIK 244 Score = 52.0 bits (123), Expect = 8e-07 Identities = 36/133 (27%), Positives = 65/133 (48%), Gaps = 2/133 (1%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVM-RRLRHP 241 YE ++ +G G + V+ + T+ + A+K++ K AV E+ ++ R H Sbjct: 454 YEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKK-------AVFDATEEVDILLRHSHHQ 506 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGL-KEDETRRIFQQLVSALTFCHAQ 418 +V+L V ++ I+++ E GG L + L E E I L++A+ + H+Q Sbjct: 507 FVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLNAVQYLHSQ 566 Query: 419 GVYHRDIKPDNLL 457 V HRD+ N+L Sbjct: 567 QVAHRDLTAANIL 579
>MAST2_MOUSE (Q60592) Microtubule-associated serine/threonine-protein kinase 2| (EC 2.7.11.1) Length = 1734 Score = 94.4 bits (233), Expect = 1e-19 Identities = 52/155 (33%), Positives = 80/155 (51%), Gaps = 2/155 (1%) Frame = +2 Query: 23 GDGAMGDRPKLPAR--YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQ 196 G G K P+ +E +KL+ G + V+L RH T++ A+K ++K+ LI +Q Sbjct: 437 GRGVSQPSQKTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQ 496 Query: 197 QIKREIAVMRRLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRI 376 Q E ++ +P +V + K + +VMEYV GG + G L D R Sbjct: 497 QAFVERDILTFAENPFVVSMFCSFETKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLY 556 Query: 377 FQQLVSALTFCHAQGVYHRDIKPDNLLVDEHGNLK 481 F + V AL + H G+ HRD+KPDNLL+ G++K Sbjct: 557 FAETVLALEYLHNYGIVHRDLKPDNLLITSMGHIK 591
>AKT2_MOUSE (Q60823) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 94.4 bits (233), Expect = 1e-19 Identities = 50/139 (35%), Positives = 76/139 (54%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 ++ +KLLG+G F KV L R T A+K++ KE +I V E V++ RHP Sbjct: 152 FDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHPF 211 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 + L R+ VMEY GG L+ H+ ED R ++VSAL + H++ V Sbjct: 212 LTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIVSALEYLHSRDV 271 Query: 425 YHRDIKPDNLLVDEHGNLK 481 +RDIK +NL++D+ G++K Sbjct: 272 VYRDIKLENLMLDKDGHIK 290
>AKT2B_XENLA (Q6IP76) RAC-beta serine/threonine-protein kinase-B (EC 2.7.11.1)| (RAC-PK-beta-B) (Protein kinase Akt-2-B) (Protein kinase B, beta-B) (PKB beta-B) Length = 485 Score = 94.0 bits (232), Expect = 2e-19 Identities = 56/157 (35%), Positives = 84/157 (53%), Gaps = 2/157 (1%) Frame = +2 Query: 17 ESGDGAMGD-RPKLPAR-YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGA 190 E D AM RPK+ ++ +KLLG+G F KV L R T A+K++ KE +I Sbjct: 138 EQMDVAMSKGRPKVTMNDFDYLKLLGKGTFGKVILVREKATGLYYAMKILRKEVIIAKDE 197 Query: 191 VQQIKREIAVMRRLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETR 370 V E V++ +HP + L R+ VMEY GG L+ H+ ED R Sbjct: 198 VAHTLTESRVLQNTKHPFLTGLKYAFQTSDRLCFVMEYANGGELFFHLSRERVFTEDRAR 257 Query: 371 RIFQQLVSALTFCHAQGVYHRDIKPDNLLVDEHGNLK 481 ++VSAL + H++ V +RDIK +NL++D+ G++K Sbjct: 258 FYGAEIVSALEYLHSRNVVYRDIKLENLMLDKDGHVK 294
>KCC1B_RAT (O70150) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase homolog) Length = 343 Score = 94.0 bits (232), Expect = 2e-19 Identities = 50/131 (38%), Positives = 77/131 (58%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 YE + LG G F++V LA+ + VA+K + K+ L G ++ EIAV+RR+ HPN Sbjct: 15 YEIREKLGSGAFSEVMLAQERGSAHLVALKCIPKKAL--RGKEALVENEIAVLRRISHPN 72 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 IV L V S +++ ME V GG L+ I G E + + Q++ A+++ H+ G+ Sbjct: 73 IVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGI 132 Query: 425 YHRDIKPDNLL 457 HRD+KP+NLL Sbjct: 133 VHRDLKPENLL 143
>KCC1B_MOUSE (Q9QYK9) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase homolog) Length = 343 Score = 94.0 bits (232), Expect = 2e-19 Identities = 50/131 (38%), Positives = 77/131 (58%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 YE + LG G F++V LA+ + VA+K + K+ L G ++ EIAV+RR+ HPN Sbjct: 15 YEIREKLGSGAFSEVMLAQERGSAHLVALKCIPKKAL--RGKEALVENEIAVLRRISHPN 72 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 IV L V S +++ ME V GG L+ I G E + + Q++ A+++ H+ G+ Sbjct: 73 IVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGI 132 Query: 425 YHRDIKPDNLL 457 HRD+KP+NLL Sbjct: 133 VHRDLKPENLL 143
>KCC1B_HUMAN (Q6P2M8) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase) Length = 343 Score = 94.0 bits (232), Expect = 2e-19 Identities = 50/131 (38%), Positives = 77/131 (58%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 YE + LG G F++V LA+ + VA+K + K+ L G ++ EIAV+RR+ HPN Sbjct: 15 YEIRERLGSGAFSEVVLAQERGSAHLVALKCIPKKAL--RGKEALVENEIAVLRRISHPN 72 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 IV L V S +++ ME V GG L+ I G E + + Q++ A+++ H+ G+ Sbjct: 73 IVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGI 132 Query: 425 YHRDIKPDNLL 457 HRD+KP+NLL Sbjct: 133 VHRDLKPENLL 143
>PK2_DICDI (P28178) Protein kinase 2 (EC 2.7.11.1)| Length = 479 Score = 94.0 bits (232), Expect = 2e-19 Identities = 43/138 (31%), Positives = 79/138 (57%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 +E + ++G+G+F KV + + A+KV+ K+ +I V K E +++ + HP Sbjct: 153 FELLNVIGKGSFGKVMQVKKKGEDKIFAMKVLRKDAIIARKQVNHTKSEKTILQCISHPF 212 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 IV LH K ++++V+++V GG L+ H+ G E + ++VSAL H Q + Sbjct: 213 IVNLHYAFQTKDKLYMVLDFVNGGELFFHLKREGRFSEPRVKIYAAEIVSALDHLHKQDI 272 Query: 425 YHRDIKPDNLLVDEHGNL 478 +RD+KP+N+L+D G++ Sbjct: 273 VYRDLKPENILLDSEGHI 290
>KS6A3_MOUSE (P18654) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B) Length = 740 Score = 94.0 bits (232), Expect = 2e-19 Identities = 45/145 (31%), Positives = 90/145 (62%), Gaps = 3/145 (2%) Frame = +2 Query: 56 PARYEQVKLLGEGNFAKVYLARHM---DTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMR 226 P+++E +K+LG+G+F KV+L + + D ++ A+KV+ K L K+ + K E ++ Sbjct: 65 PSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATL-KVRDRVRTKMERDILV 123 Query: 227 RLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTF 406 + HP IV+LH + +++++++++RGG L+ + E++ + +L AL Sbjct: 124 EVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDH 183 Query: 407 CHAQGVYHRDIKPDNLLVDEHGNLK 481 H+ G+ +RD+KP+N+L+DE G++K Sbjct: 184 LHSLGIIYRDLKPENILLDEEGHIK 208 Score = 74.7 bits (182), Expect = 1e-13 Identities = 47/139 (33%), Positives = 70/139 (50%), Gaps = 2/139 (1%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRL-RHP 241 YE + +G G+++ H T E A+K++DK K + EI ++ R +HP Sbjct: 422 YEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSK-------RDPTEEIEILLRYGQHP 474 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 NI+ L V ++VV E ++GG L I E E + + + + HAQG Sbjct: 475 NIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQG 534 Query: 422 VYHRDIKPDNLL-VDEHGN 475 V HRD+KP N+L VDE GN Sbjct: 535 VVHRDLKPSNILYVDESGN 553
>KS6A3_HUMAN (P51812) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protei Length = 740 Score = 94.0 bits (232), Expect = 2e-19 Identities = 45/145 (31%), Positives = 90/145 (62%), Gaps = 3/145 (2%) Frame = +2 Query: 56 PARYEQVKLLGEGNFAKVYLARHM---DTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMR 226 P+++E +K+LG+G+F KV+L + + D ++ A+KV+ K L K+ + K E ++ Sbjct: 65 PSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATL-KVRDRVRTKMERDILV 123 Query: 227 RLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTF 406 + HP IV+LH + +++++++++RGG L+ + E++ + +L AL Sbjct: 124 EVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDH 183 Query: 407 CHAQGVYHRDIKPDNLLVDEHGNLK 481 H+ G+ +RD+KP+N+L+DE G++K Sbjct: 184 LHSLGIIYRDLKPENILLDEEGHIK 208 Score = 74.7 bits (182), Expect = 1e-13 Identities = 47/139 (33%), Positives = 70/139 (50%), Gaps = 2/139 (1%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRL-RHP 241 YE + +G G+++ H T E A+K++DK K + EI ++ R +HP Sbjct: 422 YEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSK-------RDPTEEIEILLRYGQHP 474 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 NI+ L V ++VV E ++GG L I E E + + + + HAQG Sbjct: 475 NIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQG 534 Query: 422 VYHRDIKPDNLL-VDEHGN 475 V HRD+KP N+L VDE GN Sbjct: 535 VVHRDLKPSNILYVDESGN 553
>CRK_DAUCA (P53681) CDPK-related protein kinase (EC 2.7.11.1) (PK421)| Length = 602 Score = 94.0 bits (232), Expect = 2e-19 Identities = 53/160 (33%), Positives = 89/160 (55%), Gaps = 8/160 (5%) Frame = +2 Query: 26 DGAMGDRPKLPARYEQVKLLGEGNFAKVYLARHMDTK---EEVAIKVMDKEKLIKLGAVQ 196 D + G K +++E + +G G+F A+ + ++VA+KV+ K K+ A++ Sbjct: 135 DKSFGFSKKFGSKFEVGEEVGRGHFGYTCRAKFKKGEFKGQDVAVKVIPKAKMTTAIAIE 194 Query: 197 QIKREIAVMRRLR-HPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGG-LKEDETR 370 ++RE+ ++R L H N+VQ + + ++VVME GG L I + GG ED+ + Sbjct: 195 DVRREVKILRALTGHNNLVQFYDAFEDHTNVYVVMELCEGGELLDRILSRGGKYTEDDAK 254 Query: 371 RIFQQLVSALTFCHAQGVYHRDIKPDNLLV---DEHGNLK 481 + Q+++ + FCH QGV HRD+KP+N L DE LK Sbjct: 255 AVMIQILNVVAFCHLQGVVHRDLKPENFLFKSKDEDSQLK 294
>STK36_HUMAN (Q9NRP7) Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused| homolog) Length = 1315 Score = 94.0 bits (232), Expect = 2e-19 Identities = 52/144 (36%), Positives = 85/144 (59%), Gaps = 4/144 (2%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGA----VQQIKREIAVMRR 229 +Y ++++GEG+F +VY R + + VA+K + K LG ++ ++REI +MR Sbjct: 3 KYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPK-----LGRSEKELRNLQREIEIMRG 57 Query: 230 LRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFC 409 LRHPNIV + + VV +Y G L++ + +G L ED+ + I QLVSAL + Sbjct: 58 LRHPNIVHMLDSFETDKEVVVVTDYAEG-ELFQILEDDGKLPEDQVQAIAAQLVSALYYL 116 Query: 410 HAQGVYHRDIKPDNLLVDEHGNLK 481 H+ + HRD+KP N+L+ + G +K Sbjct: 117 HSHRILHRDMKPQNILLAKGGGIK 140
>AKT2A_XENLA (Q7ZX15) RAC-beta serine/threonine-protein kinase-A (EC 2.7.11.1)| (RAC-PK-beta-A) (Protein kinase Akt-2-A) (Protein kinase B, beta-A) (PKB beta-A) Length = 486 Score = 93.6 bits (231), Expect = 2e-19 Identities = 49/139 (35%), Positives = 76/139 (54%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 ++ +KLLG+G F KV L R T A+K++ KE +I V E V++ +HP Sbjct: 157 FDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTLTESRVLQNTKHPF 216 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 + L R+ VMEY GG L+ H+ ED R ++VSAL + H++ V Sbjct: 217 LTALKYAFQTSDRLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIVSALEYLHSRNV 276 Query: 425 YHRDIKPDNLLVDEHGNLK 481 +RDIK +NL++D+ G++K Sbjct: 277 VYRDIKLENLMLDKDGHVK 295
>IPL1_CANGA (Q6FV07) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 358 Score = 93.6 bits (231), Expect = 2e-19 Identities = 41/132 (31%), Positives = 78/132 (59%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 +E + LG+G F KVY RH + A+K ++K ++++ ++Q+KRE+ + + HPN Sbjct: 100 FEVGRKLGKGKFGKVYCVRHKKSGFICALKAIEKNEILQFNLLKQLKREVDIQLGMDHPN 159 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 I++L+ + R++++ME+ G LY+ + NG + Q+ AL + H + + Sbjct: 160 IIKLYAHFHDEKRVYLLMEHSINGELYKSLKNNGPFNDVLASHYIYQIADALHYMHKKRI 219 Query: 425 YHRDIKPDNLLV 460 HRD+KP+N+L+ Sbjct: 220 IHRDVKPENVLI 231
>AKT2_RAT (P47197) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 93.6 bits (231), Expect = 2e-19 Identities = 50/139 (35%), Positives = 75/139 (53%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 ++ +KLLG+G F KV L R T A+K++ KE +I V E V++ RHP Sbjct: 152 FDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHPF 211 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 + L R+ VMEY GG L+ H+ ED R ++VSAL + H+ V Sbjct: 212 LTALKYAFQTHDRLCFVMEYANGGDLFFHLSRERVFTEDRARFYGAEIVSALEYLHSTDV 271 Query: 425 YHRDIKPDNLLVDEHGNLK 481 +RDIK +NL++D+ G++K Sbjct: 272 VYRDIKLENLMLDKDGHIK 290
>MAST1_MOUSE (Q9R1L5) Microtubule-associated serine/threonine-protein kinase 1| (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase) Length = 1566 Score = 93.6 bits (231), Expect = 2e-19 Identities = 48/146 (32%), Positives = 79/146 (54%) Frame = +2 Query: 44 RPKLPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVM 223 +P + ++ +KL+ G + VYL RH DT++ A+K ++K+ LI +QQ E ++ Sbjct: 368 KPPGESDFDTIKLISNGAYGAVYLVRHRDTRQRFAMKKINKQNLILRNQIQQAFVERDIL 427 Query: 224 RRLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALT 403 +P +V + + + +VMEYV GG + G L + R F + V AL Sbjct: 428 TFAENPFVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNIGALPVEMARMYFAETVLALE 487 Query: 404 FCHAQGVYHRDIKPDNLLVDEHGNLK 481 + H G+ HRD+KPDNLL+ G++K Sbjct: 488 YLHNYGIVHRDLKPDNLLITSMGHIK 513
>ULK1_MOUSE (O70405) Serine/threonine-protein kinase ULK1 (EC 2.7.11.1)| (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1) Length = 1051 Score = 93.6 bits (231), Expect = 2e-19 Identities = 47/137 (34%), Positives = 79/137 (57%), Gaps = 1/137 (0%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKE-EVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHP 241 + + L+G G FA V+ RH + + EVA+K ++K+ L K + + +EI +++ L+H Sbjct: 16 FSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTL--LGKEIKILKELKHE 73 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 NIV L+ + +++VMEY GG L ++ L ED R QQ+ A+ H++G Sbjct: 74 NIVALYDFQEMANSVYLVMEYCNGGDLADYLHTMRTLSEDTVRLFLQQIAGAMRLLHSKG 133 Query: 422 VYHRDIKPDNLLVDEHG 472 + HRD+KP N+L+ G Sbjct: 134 IIHRDLKPQNILLSNPG 150
>IPL1_YARLI (Q6C3J2) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 371 Score = 93.6 bits (231), Expect = 2e-19 Identities = 46/139 (33%), Positives = 78/139 (56%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 +E K LG+G F KVYL + T A+K M+K++L++ +Q +RE+ + LRH N Sbjct: 99 FEIGKALGKGKFGKVYLVKDKKTGFVSALKCMEKKELVEGNVEKQFRREVEIQSNLRHTN 158 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 +++L K R+++++EYV G LY+ + E Q+ AL + H + + Sbjct: 159 VLRLFGHFHDKDRVYLILEYVVHGELYKLLRNQKRFTESTASSYIYQMSEALLYLHGKNI 218 Query: 425 YHRDIKPDNLLVDEHGNLK 481 HRDIKP+N+L+ + +K Sbjct: 219 IHRDIKPENILLHFNDTIK 237
>MAST1_RAT (Q810W7) Microtubule-associated serine/threonine-protein kinase 1| (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase) Length = 1570 Score = 93.6 bits (231), Expect = 2e-19 Identities = 48/146 (32%), Positives = 79/146 (54%) Frame = +2 Query: 44 RPKLPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVM 223 +P + ++ +KL+ G + VYL RH DT++ A+K ++K+ LI +QQ E ++ Sbjct: 369 KPPGESDFDTIKLISNGAYGAVYLVRHRDTRQRFAMKKINKQNLILRNQIQQAFVERDIL 428 Query: 224 RRLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALT 403 +P +V + + + +VMEYV GG + G L + R F + V AL Sbjct: 429 TFAENPFVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNIGALPVEMARMYFAETVLALE 488 Query: 404 FCHAQGVYHRDIKPDNLLVDEHGNLK 481 + H G+ HRD+KPDNLL+ G++K Sbjct: 489 YLHNYGIVHRDLKPDNLLITSMGHIK 514
>PLK4_MOUSE (Q64702) Serine/threonine-protein kinase PLK4 (EC 2.7.11.21)| (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine-protein kinase 18) Length = 925 Score = 93.2 bits (230), Expect = 3e-19 Identities = 43/135 (31%), Positives = 82/135 (60%), Gaps = 1/135 (0%) Frame = +2 Query: 80 LLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPNIVQLH 259 LLG+G+FA VY A + T EVAIK++DK+ + K G VQ+++ E+ + +L+HP++++L+ Sbjct: 17 LLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKHPSVLELY 76 Query: 260 KVMACKSRIFVVMEYVRGGPLYRHIPAN-GGLKEDETRRIFQQLVSALTFCHAQGVYHRD 436 + +++V+E G + R++ E E R Q+++ + + H+ G+ HRD Sbjct: 77 NYFEDNNYVYLVLEMCHNGEMNRYLKNRMKPFSEREARHFMHQIITGMLYLHSHGILHRD 136 Query: 437 IKPDNLLVDEHGNLK 481 + N+L+ + N+K Sbjct: 137 LTLSNILLTRNMNIK 151
>ULK1_HUMAN (O75385) Serine/threonine-protein kinase ULK1 (EC 2.7.11.1)| (Unc-51-like kinase 1) Length = 1050 Score = 93.2 bits (230), Expect = 3e-19 Identities = 47/133 (35%), Positives = 79/133 (59%), Gaps = 1/133 (0%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKE-EVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHP 241 + + L+G G FA V+ RH + + EVA+K ++K+ L K + + +EI +++ L+H Sbjct: 16 FSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTL--LGKEIKILKELKHE 73 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 NIV L+ + +++VMEY GG L ++ A L ED R QQ+ A+ H++G Sbjct: 74 NIVALYDFQEMANSVYLVMEYCNGGDLADYLHAMRTLSEDTIRLFLQQIAGAMRLLHSKG 133 Query: 422 VYHRDIKPDNLLV 460 + HRD+KP N+L+ Sbjct: 134 IIHRDLKPQNILL 146
>PEF1_SCHPO (O74456) Serine/threonine-protein kinase pef1 (EC 2.7.11.22)| (Cyclin-dependent kinase pef1) (PHO85 homolog) Length = 288 Score = 93.2 bits (230), Expect = 3e-19 Identities = 52/144 (36%), Positives = 85/144 (59%), Gaps = 5/144 (3%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVM--DKEKLIKLGAVQQIKREIAVMRRLRH 238 Y++++ LGEG +A VY ++ T E VA+KV+ D ++ G REI++M+ LRH Sbjct: 3 YQRLEKLGEGTYAHVYKGQNRVTGEIVALKVIRIDADE----GTPSTAIREISLMKELRH 58 Query: 239 PNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPA---NGGLKEDETRRIFQQLVSALTFC 409 PNI+ L V+ ++++ +V EY+ L +++ G L + + QQL+ ++FC Sbjct: 59 PNIMSLSDVLQTENKLMLVFEYMEKD-LKKYMDTYGNQGALPPSQVKNFTQQLLKGISFC 117 Query: 410 HAQGVYHRDIKPDNLLVDEHGNLK 481 H V HRD+KP NLL++ G LK Sbjct: 118 HENRVLHRDLKPQNLLINSRGELK 141
>KPCL_RAT (Q64617) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 683 Score = 93.2 bits (230), Expect = 3e-19 Identities = 51/140 (36%), Positives = 81/140 (57%), Gaps = 1/140 (0%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLR-HP 241 +E +++LG+G+F KV LAR +T E A+KV+ K+ +++ V+ E ++ R HP Sbjct: 355 FEFIRVLGKGSFGKVMLARIKETGELYAVKVLKKDVILQDDDVECTMTEKRILSLARNHP 414 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 + QL R+F VME+V GG L HI + E R +++SAL F H +G Sbjct: 415 FLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHEKG 474 Query: 422 VYHRDIKPDNLLVDEHGNLK 481 + +RD+K DN+L+D G+ K Sbjct: 475 IIYRDLKLDNVLLDHEGHCK 494
>KPCL_MOUSE (P23298) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 683 Score = 93.2 bits (230), Expect = 3e-19 Identities = 51/140 (36%), Positives = 81/140 (57%), Gaps = 1/140 (0%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLR-HP 241 +E +++LG+G+F KV LAR +T E A+KV+ K+ +++ V+ E ++ R HP Sbjct: 355 FEFIRVLGKGSFGKVMLARIKETGELYAVKVLKKDVILQDDDVECTMTEKRILSLARNHP 414 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 + QL R+F VME+V GG L HI + E R +++SAL F H +G Sbjct: 415 FLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHEKG 474 Query: 422 VYHRDIKPDNLLVDEHGNLK 481 + +RD+K DN+L+D G+ K Sbjct: 475 IIYRDLKLDNVLLDHEGHCK 494
>KS6A2_HUMAN (Q15349) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (MAP kinase-activated protein kinase 1c) (MAPKAPK1C) Length = 733 Score = 92.8 bits (229), Expect = 4e-19 Identities = 45/145 (31%), Positives = 88/145 (60%), Gaps = 3/145 (2%) Frame = +2 Query: 56 PARYEQVKLLGEGNFAKVYLARHM---DTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMR 226 P+++E +K+LG+G++ KV+L R + D + A+KV+ K L V+ K E ++ Sbjct: 56 PSQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRS-KMERDILA 114 Query: 227 RLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTF 406 + HP IV+LH + +++++++++RGG L+ + E++ + +L AL Sbjct: 115 EVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDH 174 Query: 407 CHAQGVYHRDIKPDNLLVDEHGNLK 481 H+ G+ +RD+KP+N+L+DE G++K Sbjct: 175 LHSLGIIYRDLKPENILLDEEGHIK 199 Score = 72.0 bits (175), Expect = 8e-13 Identities = 45/139 (32%), Positives = 70/139 (50%), Gaps = 2/139 (1%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRL-RHP 241 YE + +G G+++ H T E A+K++DK K + EI ++ R +HP Sbjct: 415 YEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKSK-------RDPSEEIEILLRYGQHP 467 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 NI+ L V +++VME +RGG L I E E + + + + H+QG Sbjct: 468 NIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQG 527 Query: 422 VYHRDIKPDNLLV-DEHGN 475 V HRD+KP N+L DE G+ Sbjct: 528 VVHRDLKPSNILYRDESGS 546
>AKT2_HUMAN (P31751) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 92.8 bits (229), Expect = 4e-19 Identities = 49/139 (35%), Positives = 76/139 (54%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 ++ +KLLG+G F KV L R T A+K++ KE +I V E V++ RHP Sbjct: 152 FDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHPF 211 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 + L R+ VMEY GG L+ H+ E+ R ++VSAL + H++ V Sbjct: 212 LTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLHSRDV 271 Query: 425 YHRDIKPDNLLVDEHGNLK 481 +RDIK +NL++D+ G++K Sbjct: 272 VYRDIKLENLMLDKDGHIK 290
>FUSED_DROME (P23647) Serine/threonine-protein kinase fused (EC 2.7.11.1)| Length = 805 Score = 92.8 bits (229), Expect = 4e-19 Identities = 49/140 (35%), Positives = 84/140 (60%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHP 241 RY L+G+G+F VY A D + VAIKV+ K ++ ++RE + RL+HP Sbjct: 3 RYAVSSLVGQGSFGCVYKATRKDDSKVVAIKVISKRGRATK-ELKNLRRECDIQARLKHP 61 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 +++++ + K+ +FVV E+ L+R++ NG + E+ RR+ LVSAL + H+ Sbjct: 62 HVIEMIESFESKTDLFVVTEFALMD-LHRYLSYNGAMGEEPARRVTGHLVSALYYLHSNR 120 Query: 422 VYHRDIKPDNLLVDEHGNLK 481 + HRD+KP N+L+D++ + K Sbjct: 121 ILHRDLKPQNVLLDKNMHAK 140
>KS6A2_MOUSE (Q9WUT3) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (Protein-tyrosine kinase Mpk-9) (MAP kinase-activated protein kinase 1c) (M Length = 733 Score = 92.4 bits (228), Expect = 5e-19 Identities = 45/145 (31%), Positives = 87/145 (60%), Gaps = 3/145 (2%) Frame = +2 Query: 56 PARYEQVKLLGEGNFAKVYLARHM---DTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMR 226 P+++E +K+LG+G++ KV+L R + D + A+KV+ K L V+ K E ++ Sbjct: 56 PSQFELLKVLGQGSYGKVFLVRKVTGSDAGQLYAMKVLKKATLKVRDRVRS-KMERDILA 114 Query: 227 RLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTF 406 + HP IV+LH + +++++++++RGG L+ + E++ + +L AL Sbjct: 115 EVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDH 174 Query: 407 CHAQGVYHRDIKPDNLLVDEHGNLK 481 H G+ +RD+KP+N+L+DE G++K Sbjct: 175 LHGLGIIYRDLKPENILLDEEGHIK 199 Score = 75.5 bits (184), Expect = 7e-14 Identities = 46/139 (33%), Positives = 71/139 (51%), Gaps = 2/139 (1%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRL-RHP 241 YE + +G G+++ H T E A+K++DK K + EI ++ R +HP Sbjct: 415 YEIKEDIGVGSYSVCKRCVHKATDAEYAVKIIDKSK-------RDPSEEIEILLRYGQHP 467 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 NI+ L V +++VME +RGG L I E E + + + + H+QG Sbjct: 468 NIITLKDVYDDGKYVYLVMELMRGGELLDRILRQRCFSEREASDVLYTIARTMDYLHSQG 527 Query: 422 VYHRDIKPDNLL-VDEHGN 475 V HRD+KP N+L +DE GN Sbjct: 528 VVHRDLKPSNILYMDESGN 546
>CDK5_XENLA (P51166) Cell division protein kinase 5 (EC 2.7.11.22) (Neuronal| cyclin-dependent kinase 5) Length = 292 Score = 92.4 bits (228), Expect = 5e-19 Identities = 48/140 (34%), Positives = 80/140 (57%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHP 241 +YE+++ +GEG + V+ A++ DT E VA+K + + + G REI +++ L+H Sbjct: 3 KYEKLEKIGEGTYGTVFKAKNRDTHEIVALKRVRLDDDDE-GVPSSALREICLLKELKHK 61 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 NIV+LH V+ ++ +V E+ NG L + + QL+ L FCH++ Sbjct: 62 NIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFMYQLLKGLAFCHSRN 121 Query: 422 VYHRDIKPDNLLVDEHGNLK 481 V HRD+KP NLL++ +G LK Sbjct: 122 VLHRDLKPQNLLINRNGELK 141
>TSSK4_MOUSE (Q9D411) Testis-specific serine/threonine-protein kinase 4 (EC| 2.7.11.1) (TSSK-4) (Testis-specific kinase 4) (TSK-4) Length = 328 Score = 92.4 bits (228), Expect = 5e-19 Identities = 44/139 (31%), Positives = 81/139 (58%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 YE K++G G++ VY A + K VA+K++ K+K + + + REI VM+ LRH Sbjct: 25 YEVGKIIGHGSYGTVYEAYYTKQKVMVAVKIISKKKASEDYLNKFLPREIQVMKVLRHKY 84 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 ++ ++ + SR+++++E +GG + I G E + F Q+ + + H++G+ Sbjct: 85 LINFYQAIETTSRVYIILELAQGGDVLEWIQRYGACAETLAGKWFSQMALGIAYLHSKGI 144 Query: 425 YHRDIKPDNLLVDEHGNLK 481 HRD+K +NLL+D+ N+K Sbjct: 145 VHRDLKLENLLLDKRENVK 163
>STK36_PONPY (Q5RAJ5) Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused| homolog) Length = 1315 Score = 92.4 bits (228), Expect = 5e-19 Identities = 52/144 (36%), Positives = 84/144 (58%), Gaps = 4/144 (2%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGA----VQQIKREIAVMRR 229 +Y ++++GEG+F +VY R + + VA+K + K LG ++ ++REI +MR Sbjct: 3 KYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPK-----LGRSEKELRNLQREIEIMRG 57 Query: 230 LRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFC 409 LRHPNIV + + VV +Y G L + + +G L ED+ + I QLVSAL + Sbjct: 58 LRHPNIVHMLDSFETDKEVVVVTDYAEG-ELLQILEDDGKLPEDQVQAIAAQLVSALYYL 116 Query: 410 HAQGVYHRDIKPDNLLVDEHGNLK 481 H+ + HRD+KP N+L+ + G +K Sbjct: 117 HSHRILHRDMKPQNILLAKGGGIK 140
>CDR2_SCHPO (P87050) Mitosis inducer protein kinase cdr2 (EC 2.7.11.1)| Length = 775 Score = 92.0 bits (227), Expect = 7e-19 Identities = 43/133 (32%), Positives = 77/133 (57%) Frame = +2 Query: 83 LGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPNIVQLHK 262 LG G LA+H +T + +K + + +I+ E+ ++R + HPN++QL Sbjct: 16 LGSGGPNSSRLAKHRETGQLAVVKPIVGWSELTSSQQARIEGELVLLRLIEHPNVLQLID 75 Query: 263 VMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGVYHRDIK 442 V++ + ++FVV+EY+ GG L+ + G E +T + Q++ L +CH + HRD+K Sbjct: 76 VISAQEQLFVVVEYMPGGELFDCMLRKGSFTEQDTAKFLWQILCGLEYCHKLHICHRDLK 135 Query: 443 PDNLLVDEHGNLK 481 P+NL +D HG++K Sbjct: 136 PENLYLDAHGSIK 148
>KKK1_YEAST (P34244) Probable serine/threonine-protein kinase YKL101W (EC| 2.7.11.1) Length = 1518 Score = 92.0 bits (227), Expect = 7e-19 Identities = 52/165 (31%), Positives = 88/165 (53%), Gaps = 35/165 (21%) Frame = +2 Query: 77 KLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLI----KLGAVQQ--------------- 199 K LG+G+ +V LA++M+T + AIK++ K+K G V Sbjct: 85 KTLGKGSSGRVRLAKNMETGQLAAIKIVPKKKAFVHCSNNGTVPNSYSSSMVTSNVSSPS 144 Query: 200 ----------------IKREIAVMRRLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRH 331 I+REI +M+ + H N++ L +V KS +++V+EYV GG L+ + Sbjct: 145 IASREHSNHSQTNPYGIEREIVIMKLISHTNVMALFEVWENKSELYLVLEYVDGGELFDY 204 Query: 332 IPANGGLKEDETRRIFQQLVSALTFCHAQGVYHRDIKPDNLLVDE 466 + + G L E E F+Q+V +++CH+ + HRD+KP+NLL+D+ Sbjct: 205 LVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDK 249
>YP141_YEAST (Q03002) Putative serine/threonine-protein kinase YPL141C (EC| 2.7.11.1) Length = 865 Score = 92.0 bits (227), Expect = 7e-19 Identities = 53/143 (37%), Positives = 83/143 (58%), Gaps = 11/143 (7%) Frame = +2 Query: 83 LGEGNFAKVYLA----------RHMDTKEEVAIKVMDKEKLIKLGAVQ-QIKREIAVMRR 229 LGEG F KV L D ++VAIK++ ++ + + +I REI ++ Sbjct: 47 LGEGEFGKVKLGWPKNFSNSSNSTFDFPKQVAIKLIKRDSISNDYRKEVKIYREINALKH 106 Query: 230 LRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFC 409 L HPNIV+L +V+ I +V+EY GG Y++I LKE R+F QL+S + + Sbjct: 107 LSHPNIVKLEEVLQNSRYIGIVLEYACGGEFYKYIQKKRRLKEMNACRLFSQLISGVHYI 166 Query: 410 HAQGVYHRDIKPDNLLVDEHGNL 478 H++G+ HRD+K +NLL+D++ NL Sbjct: 167 HSKGLVHRDLKLENLLLDKNENL 189
>SSP1_SCHPO (P50526) Serine/threonine-protein kinase ssp1 (EC 2.7.11.1)| Length = 652 Score = 92.0 bits (227), Expect = 7e-19 Identities = 54/148 (36%), Positives = 89/148 (60%), Gaps = 9/148 (6%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDK-EKLIKLGAV------QQIKREIAVM 223 YE +K LG G KV L R T+E +AIK++ K E+ KLG ++++REIA++ Sbjct: 135 YEIIKELGRGMHGKVKLGRDTVTRELLAIKIIPKTERRPKLGRANASSQKEKVRREIAIL 194 Query: 224 RRLRHPNIVQLHKVM--ACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSA 397 ++ HPN+V+L +V+ +++++V+EY+ GG + + L E R+ F+ +V Sbjct: 195 KKCVHPNVVRLREVIDDPSSTKVYLVLEYMSGGEVPWTDCDSPVLSISEARQYFRDVVLG 254 Query: 398 LTFCHAQGVYHRDIKPDNLLVDEHGNLK 481 L + H QG+ HRDIKP NLL++ +K Sbjct: 255 LEYLHYQGIIHRDIKPANLLLNSSNCVK 282
>KN8R_YEAST (P53739) Probable serine/threonine-protein kinase YNR047W (EC| 2.7.11.1) Length = 893 Score = 91.7 bits (226), Expect = 9e-19 Identities = 43/143 (30%), Positives = 82/143 (57%), Gaps = 2/143 (1%) Frame = +2 Query: 56 PARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLR 235 P +E+++LLG+G+ KV+L R T A+KV+ K+++IK ++++ E ++ Sbjct: 493 PQSFEKIRLLGQGDVGKVFLVREKKTNRVYALKVLSKDEMIKRNKIKRVLTEQEILATSN 552 Query: 236 HPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGG--LKEDETRRIFQQLVSALTFC 409 HP IV L+ + +++ MEY GG +R + + ED+ R ++ +AL + Sbjct: 553 HPFIVTLYHSFQSEDYLYLCMEYCMGGEFFRALQTRKTKCICEDDARFYASEVTAALEYL 612 Query: 410 HAQGVYHRDIKPDNLLVDEHGNL 478 H G +RD+KP+N+L+ + G++ Sbjct: 613 HLLGFIYRDLKPENILLHQSGHI 635
>KPCE_RABIT (P10830) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 736 Score = 91.7 bits (226), Expect = 9e-19 Identities = 56/159 (35%), Positives = 86/159 (54%), Gaps = 4/159 (2%) Frame = +2 Query: 17 ESGDGAMGDRPKLPA-RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIK---L 184 E+G+ G +L + +K+LG+G+F KV LA E A+KV+ K+ +++ + Sbjct: 390 ENGEVRQGQAKRLGLDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDV 449 Query: 185 GAVQQIKREIAVMRRLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDE 364 KR +A+ R+ HP + QL+ K R+F VMEYV GG L I + E Sbjct: 450 DCTMTEKRILALARK--HPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPR 507 Query: 365 TRRIFQQLVSALTFCHAQGVYHRDIKPDNLLVDEHGNLK 481 +R ++ SAL F H GV +RD+K DN+L+D G+ K Sbjct: 508 SRFYAAEVTSALMFLHQHGVIYRDLKLDNILLDAEGHCK 546
>TSSK1_HUMAN (Q9BXA7) Testis-specific serine/threonine-protein kinase 1 (EC| 2.7.11.1) (TSSK-1) (Testis-specific kinase 1) (TSK-1) (Serine/threonine-protein kinase 22A) Length = 367 Score = 91.7 bits (226), Expect = 9e-19 Identities = 51/134 (38%), Positives = 78/134 (58%), Gaps = 1/134 (0%) Frame = +2 Query: 83 LGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPNIVQLHK 262 LGEG++AKV A K VAIK++D++K + + REI ++ L H +I++ ++ Sbjct: 18 LGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPREIEILAMLNHCSIIKTYE 77 Query: 263 VMACK-SRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGVYHRDI 439 + ++++VME G L I G L EDE R+ F QL A+ +CH V HRD+ Sbjct: 78 IFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSLAIKYCHDLDVVHRDL 137 Query: 440 KPDNLLVDEHGNLK 481 K DNLL+D+ N+K Sbjct: 138 KCDNLLLDKDFNIK 151
>KPCE_HUMAN (Q02156) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 737 Score = 91.7 bits (226), Expect = 9e-19 Identities = 56/159 (35%), Positives = 86/159 (54%), Gaps = 4/159 (2%) Frame = +2 Query: 17 ESGDGAMGDRPKLPA-RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIK---L 184 E+G+ G +L + +K+LG+G+F KV LA E A+KV+ K+ +++ + Sbjct: 391 ENGEVRQGQAKRLGLDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDV 450 Query: 185 GAVQQIKREIAVMRRLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDE 364 KR +A+ R+ HP + QL+ K R+F VMEYV GG L I + E Sbjct: 451 DCTMTEKRILALARK--HPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPR 508 Query: 365 TRRIFQQLVSALTFCHAQGVYHRDIKPDNLLVDEHGNLK 481 +R ++ SAL F H GV +RD+K DN+L+D G+ K Sbjct: 509 SRFYAAEVTSALMFLHQHGVIYRDLKLDNILLDAEGHCK 547
>CDC2_DICDI (P34112) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 296 Score = 91.3 bits (225), Expect = 1e-18 Identities = 49/141 (34%), Positives = 81/141 (57%) Frame = +2 Query: 59 ARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRH 238 +RY++++ LGEG + KVY A+ T VA+K K +L G REI++++ + H Sbjct: 8 SRYQKLEKLGEGTYGKVYKAKEKATGRMVALK---KIRLEDDGVPSTALREISLLKEVPH 64 Query: 239 PNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQ 418 PN+V L V+ C++R+++V EY+ L +++ + L + QL+ L + H Sbjct: 65 PNVVSLFDVLHCQNRLYLVFEYL-DQDLKKYMDSVPALCPQLIKSYLYQLLKGLAYSHGH 123 Query: 419 GVYHRDIKPDNLLVDEHGNLK 481 + HRD+KP NLL+D G LK Sbjct: 124 RILHRDLKPQNLLIDRQGALK 144
>KS6A1_MOUSE (P18653) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 724 Score = 91.3 bits (225), Expect = 1e-18 Identities = 44/145 (30%), Positives = 88/145 (60%), Gaps = 3/145 (2%) Frame = +2 Query: 56 PARYEQVKLLGEGNFAKVYLARHM---DTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMR 226 P+++E +K+LG+G+F KV+L R + D+ A+KV+ K L K+ + K E ++ Sbjct: 59 PSQFELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATL-KVRDRVRTKMERDILA 117 Query: 227 RLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTF 406 + HP +V+LH + +++++++++RGG L+ + E++ + +L L Sbjct: 118 DVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDH 177 Query: 407 CHAQGVYHRDIKPDNLLVDEHGNLK 481 H+ G+ +RD+KP+N+L+DE G++K Sbjct: 178 LHSLGIIYRDLKPENILLDEEGHIK 202 Score = 73.2 bits (178), Expect = 3e-13 Identities = 46/139 (33%), Positives = 69/139 (49%), Gaps = 2/139 (1%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRL-RHP 241 Y + +G G+++ H T E A+KV+DK K + EI ++ R +HP Sbjct: 407 YVVKETIGVGSYSVCKRCVHKATNMEYAVKVIDKSK-------RDPSEEIEILLRYGQHP 459 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 NI+ L V +++V E +RGG L I E E + + + + H+QG Sbjct: 460 NIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTISKTVEYLHSQG 519 Query: 422 VYHRDIKPDNLL-VDEHGN 475 V HRD+KP N+L VDE GN Sbjct: 520 VVHRDLKPSNILYVDESGN 538
>KS6AA_CHICK (P18652) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 752 Score = 91.3 bits (225), Expect = 1e-18 Identities = 44/145 (30%), Positives = 88/145 (60%), Gaps = 3/145 (2%) Frame = +2 Query: 56 PARYEQVKLLGEGNFAKVYLARHM---DTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMR 226 P+++E +K+LG+G+F KV+L R + D+ A+KV+ K L K+ + K E ++ Sbjct: 77 PSQFELLKVLGQGSFGKVFLVRKITPPDSNHLYAMKVLKKATL-KVRDRVRTKIERDILA 135 Query: 227 RLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTF 406 + HP +V+LH + +++++++++RGG L+ + E++ + +L L Sbjct: 136 DVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDH 195 Query: 407 CHAQGVYHRDIKPDNLLVDEHGNLK 481 H+ G+ +RD+KP+N+L+DE G++K Sbjct: 196 LHSLGIIYRDLKPENILLDEEGHIK 220 Score = 73.9 bits (180), Expect = 2e-13 Identities = 46/139 (33%), Positives = 69/139 (49%), Gaps = 2/139 (1%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRL-RHP 241 Y + +G G+++ H T E A+KV+DK K + EI ++ R +HP Sbjct: 435 YVVKEAIGVGSYSVCKRCIHKTTNMEYAVKVIDKSK-------RDPSEEIEILLRYGQHP 487 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 NI+ L V +++V E +RGG L I E E + + + + H+QG Sbjct: 488 NIITLKDVYDDGKYVYLVTELMRGGELLDKILRQKFFSEREASSVLHTICKTVEYLHSQG 547 Query: 422 VYHRDIKPDNLL-VDEHGN 475 V HRD+KP N+L VDE GN Sbjct: 548 VVHRDLKPSNILYVDESGN 566
>KDC2_DROME (P16912) Protein kinase DC2 (EC 2.7.11.1)| Length = 583 Score = 90.9 bits (224), Expect = 2e-18 Identities = 41/139 (29%), Positives = 82/139 (58%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 Y+ +K +G G F +V L R +++ A+K++ ++I+L ++ +K E ++R +RHP Sbjct: 274 YQIIKTVGTGTFGRVCLCRDRISEKYCAMKILAMTEVIRLKQIEHVKNERNILREIRHPF 333 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 ++ L S ++++ +YV GG L+ ++ G + ++VSAL + H+ + Sbjct: 334 VISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGKFTSQTSNFYAAEIVSALEYLHSLQI 393 Query: 425 YHRDIKPDNLLVDEHGNLK 481 +RD+KP+NLL++ G+LK Sbjct: 394 VYRDLKPENLLINRDGHLK 412
>KS6A1_HUMAN (Q15418) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 90.9 bits (224), Expect = 2e-18 Identities = 44/145 (30%), Positives = 87/145 (60%), Gaps = 3/145 (2%) Frame = +2 Query: 56 PARYEQVKLLGEGNFAKVYLARHM---DTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMR 226 P+ +E +K+LG+G+F KV+L R + D+ A+KV+ K L K+ + K E ++ Sbjct: 59 PSHFELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATL-KVRDRVRTKMERDILA 117 Query: 227 RLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTF 406 + HP +V+LH + +++++++++RGG L+ + E++ + +L L Sbjct: 118 DVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDH 177 Query: 407 CHAQGVYHRDIKPDNLLVDEHGNLK 481 H+ G+ +RD+KP+N+L+DE G++K Sbjct: 178 LHSLGIIYRDLKPENILLDEEGHIK 202 Score = 73.9 bits (180), Expect = 2e-13 Identities = 46/139 (33%), Positives = 70/139 (50%), Gaps = 2/139 (1%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRL-RHP 241 Y + +G G++++ H T E A+KV+DK K + EI ++ R +HP Sbjct: 418 YVVKETIGVGSYSECKRCVHKATNMEYAVKVIDKSK-------RDPSEEIEILLRYGQHP 470 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 NI+ L V +++V E +RGG L I E E + + + + H+QG Sbjct: 471 NIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTIGKTVEYLHSQG 530 Query: 422 VYHRDIKPDNLL-VDEHGN 475 V HRD+KP N+L VDE GN Sbjct: 531 VVHRDLKPSNILYVDESGN 549
>KS6A6_HUMAN (Q9UK32) Ribosomal protein S6 kinase alpha-6 (EC 2.7.11.1)| (S6K-alpha 6) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4) Length = 745 Score = 90.9 bits (224), Expect = 2e-18 Identities = 46/145 (31%), Positives = 87/145 (60%), Gaps = 3/145 (2%) Frame = +2 Query: 56 PARYEQVKLLGEGNFAKVYLARHM---DTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMR 226 PA++E +K+LG+G+F KV+L R D + A+KV+ K L K+ + K E ++ Sbjct: 70 PAQFELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASL-KVRDRVRTKMERDILV 128 Query: 227 RLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTF 406 + HP IV+LH + +++++++++RGG ++ + E++ + +L AL Sbjct: 129 EVNHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDH 188 Query: 407 CHAQGVYHRDIKPDNLLVDEHGNLK 481 H G+ +RD+KP+N+L+DE G++K Sbjct: 189 LHQLGIVYRDLKPENILLDEIGHIK 213 Score = 66.6 bits (161), Expect = 3e-11 Identities = 40/132 (30%), Positives = 64/132 (48%), Gaps = 1/132 (0%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRL-RHP 241 YE + +G G+++ H T E A+K++DK K + EI ++ R +HP Sbjct: 426 YELKEDIGVGSYSVCKRCIHATTNMEFAVKIIDKSK-------RDPSEEIEILMRYGQHP 478 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 NI+ L V +++V + ++GG L I E E I + + + H QG Sbjct: 479 NIITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHCQG 538 Query: 422 VYHRDIKPDNLL 457 V HRD+KP N+L Sbjct: 539 VVHRDLKPSNIL 550
>KPCE_MOUSE (P16054) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 737 Score = 90.9 bits (224), Expect = 2e-18 Identities = 56/159 (35%), Positives = 86/159 (54%), Gaps = 4/159 (2%) Frame = +2 Query: 17 ESGDGAMGDRPKLPA-RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIK---L 184 E+G+ G +L + +K+LG+G+F KV LA E A+KV+ K+ +++ + Sbjct: 391 ENGEVRPGQAKRLGLDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDV 450 Query: 185 GAVQQIKREIAVMRRLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDE 364 KR +A+ R+ HP + QL+ K R+F VMEYV GG L I + E Sbjct: 451 DCTMTEKRILALARK--HPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPR 508 Query: 365 TRRIFQQLVSALTFCHAQGVYHRDIKPDNLLVDEHGNLK 481 +R ++ SAL F H GV +RD+K DN+L+D G+ K Sbjct: 509 SRFYAAEVTSALMFLHQHGVIYRDLKLDNILLDAEGHCK 547
>CDPK4_PLAF7 (Q8IBS5) Calcium-dependent protein kinase 4 (EC 2.7.11.1)| Length = 527 Score = 90.5 bits (223), Expect = 2e-18 Identities = 43/134 (32%), Positives = 82/134 (61%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHP 241 +Y+ +K+LG+G+F +V L+R T E AIKV+ K+ + + + + RE+ +++ L H Sbjct: 68 QYKGIKILGKGSFGEVILSRDKHTGHEYAIKVISKKHVKRKTDKESLLREVELLKMLDHI 127 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 NI++L++ + ++V + GG L+ I + E + RI +Q++S +T+ H Sbjct: 128 NIMKLYEFFEDNNYYYLVSDVYTGGELFDEIISRKRFYEIDAARIIKQILSGITYMHKNN 187 Query: 422 VYHRDIKPDNLLVD 463 V HRD+KP+N+L++ Sbjct: 188 VVHRDLKPENILLE 201
>KKCC2_MOUSE (Q8C078) Calcium/calmodulin-dependent protein kinase kinase 2 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta) Length = 588 Score = 90.5 bits (223), Expect = 2e-18 Identities = 52/158 (32%), Positives = 87/158 (55%), Gaps = 25/158 (15%) Frame = +2 Query: 83 LGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKL-----------------------GAV 193 +G+G++ V LA + + A+KV+ K+KLI+ G + Sbjct: 171 IGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGARPAPGGCIQPRGPI 230 Query: 194 QQIKREIAVMRRLRHPNIVQLHKVM--ACKSRIFVVMEYVRGGPLYRHIPANGGLKEDET 367 +Q+ +EIA++++L HPN+V+L +V+ + +++V E V GP+ +P L ED+ Sbjct: 231 EQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVME-VPTLKPLSEDQA 289 Query: 368 RRIFQQLVSALTFCHAQGVYHRDIKPDNLLVDEHGNLK 481 R FQ L+ + + H Q + HRDIKP NLLV E G++K Sbjct: 290 RFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIK 327
>KKCC2_HUMAN (Q96RR4) Calcium/calmodulin-dependent protein kinase kinase 2 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta) Length = 588 Score = 90.5 bits (223), Expect = 2e-18 Identities = 52/158 (32%), Positives = 87/158 (55%), Gaps = 25/158 (15%) Frame = +2 Query: 83 LGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKL-----------------------GAV 193 +G+G++ V LA + + A+KV+ K+KLI+ G + Sbjct: 171 IGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRPAPGGCIQPRGPI 230 Query: 194 QQIKREIAVMRRLRHPNIVQLHKVM--ACKSRIFVVMEYVRGGPLYRHIPANGGLKEDET 367 +Q+ +EIA++++L HPN+V+L +V+ + +++V E V GP+ +P L ED+ Sbjct: 231 EQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVME-VPTLKPLSEDQA 289 Query: 368 RRIFQQLVSALTFCHAQGVYHRDIKPDNLLVDEHGNLK 481 R FQ L+ + + H Q + HRDIKP NLLV E G++K Sbjct: 290 RFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIK 327
>KIN1_SCHPO (P22987) Protein kinase kin1 (EC 2.7.11.1)| Length = 891 Score = 90.5 bits (223), Expect = 2e-18 Identities = 55/172 (31%), Positives = 88/172 (51%), Gaps = 18/172 (10%) Frame = +2 Query: 20 SGDGAMGDRPKLPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVM-----DKEKLIKL 184 S D +R K+ Y K +G G+ KV +A H+ T E+ AIK++ D K Sbjct: 110 SADEKPRERRKVIGNYVLGKTIGAGSMGKVKVAHHLKTGEQFAIKIVTRLHPDITKAKAA 169 Query: 185 GAVQQIK-------------REIAVMRRLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLY 325 + + K RE A+ LRHP I + V S ++V E+V GG + Sbjct: 170 ASAEATKAAQSEKNKEIRTVREAALSTLLRHPYICEARDVYITNSHYYMVFEFVDGGQML 229 Query: 326 RHIPANGGLKEDETRRIFQQLVSALTFCHAQGVYHRDIKPDNLLVDEHGNLK 481 +I ++G LKE + R+ +Q+ SAL++ H V HRD+K +N+L+ + G++K Sbjct: 230 DYIISHGKLKEKQARKFVRQIGSALSYLHQNSVVHRDLKIENILISKTGDIK 281
>KS6A1_RAT (Q63531) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 90.5 bits (223), Expect = 2e-18 Identities = 44/145 (30%), Positives = 86/145 (59%), Gaps = 3/145 (2%) Frame = +2 Query: 56 PARYEQVKLLGEGNFAKVYLARHM---DTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMR 226 P+ +E +K+LG+G+F KV+L R + D A+KV+ K L K+ + K E ++ Sbjct: 59 PSHFELLKVLGQGSFGKVFLVRKVTRPDNGHLYAMKVLKKATL-KVRDRVRTKMERDILA 117 Query: 227 RLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTF 406 + HP +V+LH + +++++++++RGG L+ + E++ + +L L Sbjct: 118 DVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDH 177 Query: 407 CHAQGVYHRDIKPDNLLVDEHGNLK 481 H+ G+ +RD+KP+N+L+DE G++K Sbjct: 178 LHSLGIIYRDLKPENILLDEEGHIK 202 Score = 73.2 bits (178), Expect = 3e-13 Identities = 45/133 (33%), Positives = 67/133 (50%), Gaps = 2/133 (1%) Frame = +2 Query: 83 LGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRL-RHPNIVQLH 259 +G G+++ H T E A+KV+DK K + EI ++ R +HPNI+ L Sbjct: 424 IGVGSYSVCKRCVHKATNMEYAVKVIDKSK-------RDPSEEIEILLRYGQHPNIITLK 476 Query: 260 KVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGVYHRDI 439 V +++V E +RGG L I E E + + + + H+QGV HRD+ Sbjct: 477 DVYDDSKHVYLVTELMRGGELLDKILRQKFFSEREASFVLYTISKTVEYLHSQGVVHRDL 536 Query: 440 KPDNLL-VDEHGN 475 KP N+L VDE GN Sbjct: 537 KPSNILYVDESGN 549
>KPCL_HUMAN (P24723) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 682 Score = 90.5 bits (223), Expect = 2e-18 Identities = 50/140 (35%), Positives = 80/140 (57%), Gaps = 1/140 (0%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLR-HP 241 +E +++LG+G+F KV LAR +T + A+KV+ K+ ++ V+ E ++ R HP Sbjct: 354 FEFIRVLGKGSFGKVMLARVKETGDLYAVKVLKKDVILLDDDVECTMTEKRILSLARNHP 413 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 + QL R+F VME+V GG L HI + E R +++SAL F H +G Sbjct: 414 FLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHDKG 473 Query: 422 VYHRDIKPDNLLVDEHGNLK 481 + +RD+K DN+L+D G+ K Sbjct: 474 IIYRDLKLDNVLLDHEGHCK 493
>STK36_MOUSE (Q69ZM6) Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused| homolog) Length = 1268 Score = 90.5 bits (223), Expect = 2e-18 Identities = 51/144 (35%), Positives = 84/144 (58%), Gaps = 4/144 (2%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGA----VQQIKREIAVMRR 229 +Y ++++GEG+F +VY R + + VA+K + K LG ++ ++REI +MR Sbjct: 3 KYHVLEMIGEGSFGRVYKGRKKYSAQVVALKFIPK-----LGRSEKELRNLQREIEIMRG 57 Query: 230 LRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFC 409 L HPNIV + + VV +Y G L++ + +G L ED+ + I QLVSAL + Sbjct: 58 LWHPNIVHMLDSFETDKEVVVVTDYAEG-ELFQILEDDGKLPEDQVQAIAAQLVSALYYL 116 Query: 410 HAQGVYHRDIKPDNLLVDEHGNLK 481 H+ + HRD+KP N+L+ + G +K Sbjct: 117 HSHRILHRDMKPQNILLAKGGGIK 140
>KCC1_YEAST (P27466) Calcium/calmodulin-dependent protein kinase I (EC| 2.7.11.17) Length = 446 Score = 90.5 bits (223), Expect = 2e-18 Identities = 47/134 (35%), Positives = 79/134 (58%), Gaps = 2/134 (1%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQ--QIKREIAVMRRLR 235 +Y K LG G F V A++ +T E+VA+K++ K K +K VQ + E+ +++RL Sbjct: 36 KYVFGKTLGAGTFGVVRQAKNTETGEDVAVKILIK-KALKGNKVQLEALYDELDILQRLH 94 Query: 236 HPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHA 415 HPNIV K + +++ + +GG L+ I G E++ RI +++SA+ + H+ Sbjct: 95 HPNIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVRILVEILSAVKYMHS 154 Query: 416 QGVYHRDIKPDNLL 457 Q + HRD+KP+NLL Sbjct: 155 QNIVHRDLKPENLL 168
>ST32C_MOUSE (Q8QZV4) Serine/threonine-protein kinase 32C (EC 2.7.11.1)| Length = 488 Score = 90.5 bits (223), Expect = 2e-18 Identities = 42/137 (30%), Positives = 82/137 (59%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 ++ ++ +G+G+F KV + + DT++ A+K M+K++ I+ V+ + RE+ +++ + H Sbjct: 94 FQILRAIGKGSFGKVCIVQKRDTEKMYAMKYMNKQQCIERDEVRNVFRELEILQEIEHVF 153 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 +V L + +F+V++ + GG L H+ N ED R ++ AL + +Q + Sbjct: 154 LVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVQFSEDTVRLYICEMALALDYLRSQHI 213 Query: 425 YHRDIKPDNLLVDEHGN 475 HRD+KPDN+L+DE G+ Sbjct: 214 IHRDVKPDNILLDEQGH 230
>AKT1_BOVIN (Q01314) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) Length = 480 Score = 90.5 bits (223), Expect = 2e-18 Identities = 49/140 (35%), Positives = 77/140 (55%), Gaps = 1/140 (0%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 +E VKLLG+G F KV L + T A+K++ KE ++ V E V++ RHP+ Sbjct: 150 FEYVKLLGKGTFGKVILVKEKATAAYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPS 209 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQ-G 421 + L R+ VMEY GG L+ H+ ED R ++VSAL + H++ Sbjct: 210 LTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKE 269 Query: 422 VYHRDIKPDNLLVDEHGNLK 481 V +RD+K +NL++D+ G++K Sbjct: 270 VVYRDLKLENLMLDKDGHIK 289
>KKCC2_RAT (O88831) Calcium/calmodulin-dependent protein kinase kinase 2 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta) Length = 587 Score = 90.5 bits (223), Expect = 2e-18 Identities = 52/158 (32%), Positives = 87/158 (55%), Gaps = 25/158 (15%) Frame = +2 Query: 83 LGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKL-----------------------GAV 193 +G+G++ V LA + + A+KV+ K+KLI+ G + Sbjct: 170 IGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRPAPGGCIQPRGPI 229 Query: 194 QQIKREIAVMRRLRHPNIVQLHKVM--ACKSRIFVVMEYVRGGPLYRHIPANGGLKEDET 367 +Q+ +EIA++++L HPN+V+L +V+ + +++V E V GP+ +P L ED+ Sbjct: 230 EQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVME-VPTLKPLSEDQA 288 Query: 368 RRIFQQLVSALTFCHAQGVYHRDIKPDNLLVDEHGNLK 481 R FQ L+ + + H Q + HRDIKP NLLV E G++K Sbjct: 289 RFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIK 326
>PAK1_YEAST (P38990) Serine/threonine-protein kinase PAK1 (EC 2.7.11.1)| Length = 1142 Score = 90.5 bits (223), Expect = 2e-18 Identities = 63/160 (39%), Positives = 88/160 (55%), Gaps = 21/160 (13%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKE-----------KLIKLGAVQQIKRE 211 YE +K LG G KV LAR + +K+ VAIK++D+ K K+ +IKRE Sbjct: 133 YEIIKELGHGQHGKVKLARDILSKQLVAIKIVDRHEKKQRKFFTFIKSSKISENDKIKRE 192 Query: 212 IAVMRRLRHPNIVQLHKVMA-CKSR-IFVVMEYVRGG------PLYRHIPANGG--LKED 361 IA+M++ H ++VQL +V+ KSR I++V+EY G P A G L Sbjct: 193 IAIMKKCHHKHVVQLIEVLDDLKSRKIYLVLEYCSRGEVKWCPPDCMESDAKGPSLLSFQ 252 Query: 362 ETRRIFQQLVSALTFCHAQGVYHRDIKPDNLLVDEHGNLK 481 ETR I + +V L + H QG+ HRDIKP NLL+ G +K Sbjct: 253 ETREILRGVVLGLEYLHYQGIIHRDIKPANLLISGDGTVK 292
>CDK5_RAT (Q03114) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) Length = 292 Score = 90.1 bits (222), Expect = 3e-18 Identities = 47/140 (33%), Positives = 81/140 (57%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHP 241 +YE+++ +GEG + V+ A++ +T E VA+K + + + G REI +++ L+H Sbjct: 3 KYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDE-GVPSSALREICLLKELKHK 61 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 NIV+LH V+ ++ +V E+ NG L + + + QL+ L FCH++ Sbjct: 62 NIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSLLFQLLKGLGFCHSRN 121 Query: 422 VYHRDIKPDNLLVDEHGNLK 481 V HRD+KP NLL++ +G LK Sbjct: 122 VLHRDLKPQNLLINRNGELK 141
>ST32C_HUMAN (Q86UX6) Serine/threonine-protein kinase 32C (EC 2.7.11.1) (PKE)| (YANK3) Length = 486 Score = 90.1 bits (222), Expect = 3e-18 Identities = 42/137 (30%), Positives = 81/137 (59%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 ++ ++ +G+G+F KV + + DT++ A+K M+K++ I+ V+ + RE+ +++ + H Sbjct: 93 FQILRAIGKGSFGKVCIVQKRDTEKMYAMKYMNKQQCIERDEVRNVFRELEILQEIEHVF 152 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 +V L + +F+V++ + GG L H+ N ED R ++ AL + Q + Sbjct: 153 LVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVQFSEDTVRLYICEMALALDYLRGQHI 212 Query: 425 YHRDIKPDNLLVDEHGN 475 HRD+KPDN+L+DE G+ Sbjct: 213 IHRDVKPDNILLDERGH 229
>KPC3_CAEEL (Q19266) Protein kinase C-like 3 (EC 2.7.11.13) (Atypical protein| kinase C-3) (aPKC3) Length = 597 Score = 90.1 bits (222), Expect = 3e-18 Identities = 46/140 (32%), Positives = 82/140 (58%), Gaps = 1/140 (0%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRL-RHP 241 + + ++G G++AKV A H+ T++ AIK++ KE + + ++ E +V +P Sbjct: 253 FRLLTVIGRGSYAKVVQAEHVSTRQIYAIKIIKKEMFNEDEDIDWVQTEKSVFEAASNYP 312 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 +V LH +SR+F V+E+V GG L H+ L E+ R +++ AL F H++G Sbjct: 313 FLVGLHSCFQTESRLFFVIEFVPGGDLMFHMQQQRKLPEEHARFYSGEIILALHFLHSRG 372 Query: 422 VYHRDIKPDNLLVDEHGNLK 481 + +RD+K DN+L+D G++K Sbjct: 373 IIYRDLKLDNVLIDAEGHIK 392
>CDPK4_PLAYO (Q7RJG2) Calcium-dependent protein kinase 4 (EC 2.7.11.1)| Length = 527 Score = 90.1 bits (222), Expect = 3e-18 Identities = 43/134 (32%), Positives = 82/134 (61%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHP 241 +Y+ +K+LG+G+F +V L++ T E AIKV+ K+ + + Q + RE+ +++ L H Sbjct: 68 QYKGIKILGKGSFGEVILSKDKHTGHEYAIKVISKKHVKRKTDKQSLLREVELLKMLDHI 127 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 NI++L++ + ++V + GG L+ I + E + RI +Q++S +T+ H Sbjct: 128 NIMKLYEFFEDNNYYYLVSDVYSGGELFDEIISRKRFYEVDAARIIKQVLSGITYMHKNN 187 Query: 422 VYHRDIKPDNLLVD 463 V HRD+KP+N+L++ Sbjct: 188 VVHRDLKPENILLE 201
>CDPK4_PLABA (P62345) Calcium-dependent protein kinase 4 (EC 2.7.11.1) (PbCDPK4)| Length = 527 Score = 90.1 bits (222), Expect = 3e-18 Identities = 43/134 (32%), Positives = 82/134 (61%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHP 241 +Y+ +K+LG+G+F +V L++ T E AIKV+ K+ + + Q + RE+ +++ L H Sbjct: 68 QYKGIKILGKGSFGEVILSKDKHTGHEYAIKVISKKHVKRKTDKQSLLREVELLKMLDHI 127 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 NI++L++ + ++V + GG L+ I + E + RI +Q++S +T+ H Sbjct: 128 NIMKLYEFFEDNNYYYLVSDVYSGGELFDEIISRKRFYEVDAARIIKQVLSGITYMHKNN 187 Query: 422 VYHRDIKPDNLLVD 463 V HRD+KP+N+L++ Sbjct: 188 VVHRDLKPENILLE 201
>NRC2_NEUCR (O42626) Serine/threonine-protein kinase nrc-2 (EC 2.7.11.1)| (Nonrepressible conidiation protein 2) Length = 623 Score = 90.1 bits (222), Expect = 3e-18 Identities = 42/143 (29%), Positives = 82/143 (57%), Gaps = 2/143 (1%) Frame = +2 Query: 56 PARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLR 235 P ++++KL+G+G+ KVYL + + A+KV+ K+++IK +++ E ++ Sbjct: 239 PQSFDKIKLIGKGDVGKVYLVKEKKSGRLYAMKVLSKKEMIKRNKIKRALAEQEILATSN 298 Query: 236 HPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGG--LKEDETRRIFQQLVSALTFC 409 HP IV L+ + +++ MEY GG +R + G + ED+ R ++ +AL + Sbjct: 299 HPFIVTLYHSFQSEDYLYLCMEYCSGGEFFRALQTRPGKCIPEDDARFYAAEVTAALEYL 358 Query: 410 HAQGVYHRDIKPDNLLVDEHGNL 478 H G +RD+KP+N+L+ + G++ Sbjct: 359 HLMGFIYRDLKPENILLHQSGHI 381
>CDC2_HUMAN (P06493) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 89.7 bits (221), Expect = 4e-18 Identities = 47/141 (33%), Positives = 78/141 (55%), Gaps = 2/141 (1%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 Y +++ +GEG + VY RH T + VA+K + E + G REI++++ LRHPN Sbjct: 4 YTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEE-GVPSTAIREISLLKELRHPN 62 Query: 245 IVQLHKVMACKSRIFVVMEYVRGG--PLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQ 418 IV L V+ SR++++ E++ IP + + Q++ + FCH++ Sbjct: 63 IVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSR 122 Query: 419 GVYHRDIKPDNLLVDEHGNLK 481 V HRD+KP NLL+D+ G +K Sbjct: 123 RVLHRDLKPQNLLIDDKGTIK 143
>CDC2_BOVIN (P48734) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 89.7 bits (221), Expect = 4e-18 Identities = 47/141 (33%), Positives = 78/141 (55%), Gaps = 2/141 (1%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 Y +++ +GEG + VY RH T + VA+K + E + G REI++++ LRHPN Sbjct: 4 YTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEE-GVPSTAIREISLLKELRHPN 62 Query: 245 IVQLHKVMACKSRIFVVMEYVRGG--PLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQ 418 IV L V+ SR++++ E++ IP + + Q++ + FCH++ Sbjct: 63 IVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQFMDSSLVKSYLYQILQGIVFCHSR 122 Query: 419 GVYHRDIKPDNLLVDEHGNLK 481 V HRD+KP NLL+D+ G +K Sbjct: 123 RVLHRDLKPQNLLIDDKGTIK 143
>YP150_YEAST (Q12152) Putative serine/threonine-protein kinase YPL150W (EC| 2.7.11.1) Length = 901 Score = 89.7 bits (221), Expect = 4e-18 Identities = 47/139 (33%), Positives = 79/139 (56%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 Y+ +K +GEG+F KVYLA H T +V +K DK I RE+ R+ P Sbjct: 41 YKILKQIGEGSFGKVYLALHRPTHRKVCLKTSDKND-------PNIVREVFYHRQFDFPY 93 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 I +L++V+ +S++++ +EY G LY H+ + + E +F Q+ A+ + H+ Sbjct: 94 ITKLYEVIVTESKVWMALEYCPGKELYDHLLSLRRISLLECGELFAQISGAVYYAHSMHC 153 Query: 425 YHRDIKPDNLLVDEHGNLK 481 HRD+K +N+L+D++GN K Sbjct: 154 VHRDLKLENILLDKNGNAK 172
>KCC1A_HUMAN (Q14012) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 370 Score = 89.7 bits (221), Expect = 4e-18 Identities = 48/131 (36%), Positives = 77/131 (58%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 Y+ +LG G F++V LA T++ VAIK + KE L G ++ EIAV+ +++HPN Sbjct: 20 YDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALE--GKEGSMENEIAVLHKIKHPN 77 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 IV L + ++++M+ V GG L+ I G E + R+ Q++ A+ + H G+ Sbjct: 78 IVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGI 137 Query: 425 YHRDIKPDNLL 457 HRD+KP+NLL Sbjct: 138 VHRDLKPENLL 148
>CDK5_MOUSE (P49615) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) (CRK6) Length = 292 Score = 89.4 bits (220), Expect = 5e-18 Identities = 47/140 (33%), Positives = 80/140 (57%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHP 241 +YE+++ +GEG + V+ A++ +T E VA+K + + + G REI +++ L+H Sbjct: 3 KYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDE-GVPSSALREICLLKELKHK 61 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 NIV+LH V+ ++ +V E+ NG L + + QL+ L FCH++ Sbjct: 62 NIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRN 121 Query: 422 VYHRDIKPDNLLVDEHGNLK 481 V HRD+KP NLL++ +G LK Sbjct: 122 VLHRDLKPQNLLINRNGELK 141
>CDK5_HUMAN (Q00535) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) Length = 292 Score = 89.4 bits (220), Expect = 5e-18 Identities = 47/140 (33%), Positives = 80/140 (57%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHP 241 +YE+++ +GEG + V+ A++ +T E VA+K + + + G REI +++ L+H Sbjct: 3 KYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDE-GVPSSALREICLLKELKHK 61 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 NIV+LH V+ ++ +V E+ NG L + + QL+ L FCH++ Sbjct: 62 NIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRN 121 Query: 422 VYHRDIKPDNLLVDEHGNLK 481 V HRD+KP NLL++ +G LK Sbjct: 122 VLHRDLKPQNLLINRNGELK 141
>CDK5_BOVIN (Q02399) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Proline-directed protein kinase 33 kDa subunit) (PDPK) Length = 292 Score = 89.4 bits (220), Expect = 5e-18 Identities = 47/140 (33%), Positives = 80/140 (57%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHP 241 +YE+++ +GEG + V+ A++ +T E VA+K + + + G REI +++ L+H Sbjct: 3 KYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDE-GVPSSALREICLLKELKHK 61 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 NIV+LH V+ ++ +V E+ NG L + + QL+ L FCH++ Sbjct: 62 NIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRN 121 Query: 422 VYHRDIKPDNLLVDEHGNLK 481 V HRD+KP NLL++ +G LK Sbjct: 122 VLHRDLKPQNLLINRNGELK 141
>DAPK3_RAT (O88764) Death-associated protein kinase 3 (EC 2.7.11.1) (DAP| kinase 3) (DAP-like kinase) (Dlk) (ZIP-kinase) Length = 448 Score = 89.4 bits (220), Expect = 5e-18 Identities = 46/139 (33%), Positives = 81/139 (58%), Gaps = 4/139 (2%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLG---AVQQIKREIAVMRRLR 235 YE + LG G FA V + T E A K + K +L + ++I+RE++++R +R Sbjct: 13 YEMGEELGSGQFAIVRKCQQKGTGMEYAAKFIKKRRLPSSRRGVSREEIEREVSILREIR 72 Query: 236 HPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHA 415 HPNI+ LH V K+ + +++E V GG L+ + L EDE + +Q++ + + H+ Sbjct: 73 HPNIITLHDVFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLHS 132 Query: 416 QGVYHRDIKPDN-LLVDEH 469 + + H D+KP+N +L+D+H Sbjct: 133 KRIAHFDLKPENIMLLDKH 151
>DAPK3_MOUSE (O54784) Death-associated protein kinase 3 (EC 2.7.11.1) (DAP| kinase 3) (DAP-like kinase) (Dlk) (ZIP-kinase) Length = 448 Score = 89.4 bits (220), Expect = 5e-18 Identities = 46/139 (33%), Positives = 81/139 (58%), Gaps = 4/139 (2%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLG---AVQQIKREIAVMRRLR 235 YE + LG G FA V + T E A K + K +L + ++I+RE++++R +R Sbjct: 13 YEMGEELGSGQFAIVRKCQQKGTGMEYAAKFIKKRRLPSSRRGVSREEIEREVSILREIR 72 Query: 236 HPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHA 415 HPNI+ LH V K+ + +++E V GG L+ + L EDE + +Q++ + + H+ Sbjct: 73 HPNIITLHDVFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLHS 132 Query: 416 QGVYHRDIKPDN-LLVDEH 469 + + H D+KP+N +L+D+H Sbjct: 133 KRIAHFDLKPENIMLLDKH 151
>TSSK4_HUMAN (Q6SA08) Testis-specific serine/threonine-protein kinase 4 (EC| 2.7.11.1) (TSSK-4) (Testis-specific kinase 4) (TSK-4) (Serine/threonine-protein kinase 22E) Length = 328 Score = 89.0 bits (219), Expect = 6e-18 Identities = 44/139 (31%), Positives = 78/139 (56%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 YE K +G G++ VY A + K VA+K++ K+K + + REI VM+ LRH Sbjct: 25 YEVGKAIGHGSYGSVYEAFYTKQKVMVAVKIISKKKASDDYLNKFLPREIQVMKVLRHKY 84 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 ++ ++ + SR+++++E +GG + I G E + F QL + + H++ + Sbjct: 85 LINFYRAIESTSRVYIILELAQGGDVLEWIQRYGACSEPLAGKWFSQLTLGIAYLHSKSI 144 Query: 425 YHRDIKPDNLLVDEHGNLK 481 HRD+K +NLL+D+ N+K Sbjct: 145 VHRDLKLENLLLDKWENVK 163
>KPC2_APLCA (Q16975) Calcium-independent protein kinase C (EC 2.7.11.13) (APL| II) Length = 743 Score = 89.0 bits (219), Expect = 6e-18 Identities = 51/137 (37%), Positives = 73/137 (53%), Gaps = 1/137 (0%) Frame = +2 Query: 74 VKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMR-RLRHPNIV 250 +K+LG+G+F KV LA T E AIKV+ K+ +I+ V+ E ++ +HP + Sbjct: 406 IKVLGKGSFGKVMLAEKKGTDEVYAIKVLKKDVIIQDDDVECTMTEKRILALSAKHPFLT 465 Query: 251 QLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGVYH 430 LH K R+F VMEYV GG L I E R ++ AL F H G+ + Sbjct: 466 ALHSSFQTKERLFFVMEYVNGGDLMFQIQRARKFDEPRARFYAAEVTLALMFLHRHGIIY 525 Query: 431 RDIKPDNLLVDEHGNLK 481 RD+K DN+L+D G+ K Sbjct: 526 RDLKLDNILLDAEGHCK 542
>CDKL1_RAT (Q66HE7) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| Length = 352 Score = 89.0 bits (219), Expect = 6e-18 Identities = 49/143 (34%), Positives = 82/143 (57%), Gaps = 3/143 (2%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVM---DKEKLIKLGAVQQIKREIAVMRRL 232 +YE++ +GEG++ V+ R+ DT + VAIK + + +IK A+ REI ++++L Sbjct: 3 KYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKRFLETEDDPVIKKIAL----REIRMLKQL 58 Query: 233 RHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCH 412 +HPN+V L +V K R+ +V EY L+ G+ E + I Q + A+ FCH Sbjct: 59 KHPNLVSLLEVFRRKRRLHLVFEYCHHTVLHELDRYQRGVPEPLVKNITWQTLQAVNFCH 118 Query: 413 AQGVYHRDIKPDNLLVDEHGNLK 481 HRD+KP+N+L+ +H +K Sbjct: 119 KHNCIHRDVKPENILITKHSVIK 141
>KPSH2_HUMAN (Q96QS6) Serine/threonine-protein kinase H2 (EC 2.7.11.1) (PSK-H2)| Length = 385 Score = 89.0 bits (219), Expect = 6e-18 Identities = 48/138 (34%), Positives = 81/138 (58%), Gaps = 1/138 (0%) Frame = +2 Query: 47 PKLPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMD-KEKLIKLGAVQQIKREIAVM 223 P++ ARY+ L+G G+F++V TK+ AIKVM+ +E+ + V E++V+ Sbjct: 57 PRVLARYDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGREACVS----ELSVL 112 Query: 224 RRLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALT 403 RR+ H IVQL ++ + ++++VME GG L+ + A G E + RI Q + + Sbjct: 113 RRVSHRYIVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIR 172 Query: 404 FCHAQGVYHRDIKPDNLL 457 + HA + HR++KP+NLL Sbjct: 173 YLHALQITHRNLKPENLL 190
>DAPK3_HUMAN (O43293) Death-associated protein kinase 3 (EC 2.7.11.1) (DAP| kinase 3) (DAP-like kinase) (Dlk) (ZIP-kinase) Length = 454 Score = 89.0 bits (219), Expect = 6e-18 Identities = 43/135 (31%), Positives = 78/135 (57%), Gaps = 3/135 (2%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLG---AVQQIKREIAVMRRLR 235 YE + LG G FA V R T +E A K + K +L + ++I+RE+ ++R +R Sbjct: 13 YEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREIR 72 Query: 236 HPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHA 415 HPNI+ LH + K+ + +++E V GG L+ + L EDE + +Q++ + + H+ Sbjct: 73 HPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLHS 132 Query: 416 QGVYHRDIKPDNLLV 460 + + H D+KP+N+++ Sbjct: 133 KRIAHFDLKPENIML 147
>CDPK3_ORYSA (P53684) Calcium-dependent protein kinase, isoform 11 (EC 2.7.11.1)| (CDPK 11) Length = 542 Score = 88.6 bits (218), Expect = 8e-18 Identities = 49/134 (36%), Positives = 73/134 (54%), Gaps = 2/134 (1%) Frame = +2 Query: 83 LGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLR-HPNIVQLH 259 LG+G F YL ++T E A K + K KLI V+ ++REI +M L H N+V + Sbjct: 85 LGQGQFGTTYLCTEINTGCEYACKTIPKRKLITKEDVEDVRREIQIMHHLSGHKNVVAIK 144 Query: 260 KVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGVYHRDI 439 V + +VME GG L+ I G E + + + +VS + CH+ GV HRD+ Sbjct: 145 DVYEDGQAVHIVMELCAGGELFDRIQEKGHYSERKAAELIRIIVSIVAMCHSLGVMHRDL 204 Query: 440 KPDN-LLVDEHGNL 478 KP+N LL+D+ +L Sbjct: 205 KPENFLLLDKDDDL 218
>AKT1_RAT (P47196) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) Length = 480 Score = 88.6 bits (218), Expect = 8e-18 Identities = 48/140 (34%), Positives = 76/140 (54%), Gaps = 1/140 (0%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 +E +KLLG+G F KV L + T A+K++ KE ++ V E V++ RHP Sbjct: 150 FEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPF 209 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQ-G 421 + L R+ VMEY GG L+ H+ ED R ++VSAL + H++ Sbjct: 210 LTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKN 269 Query: 422 VYHRDIKPDNLLVDEHGNLK 481 V +RD+K +NL++D+ G++K Sbjct: 270 VVYRDLKLENLMLDKDGHIK 289
>AKT1_MOUSE (P31750) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (AKT1 kinase) (Protein kinase B) (PKB) (C-AKT) (Thymoma viral proto-oncogene) Length = 480 Score = 88.6 bits (218), Expect = 8e-18 Identities = 48/140 (34%), Positives = 76/140 (54%), Gaps = 1/140 (0%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 +E +KLLG+G F KV L + T A+K++ KE ++ V E V++ RHP Sbjct: 150 FEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPF 209 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQ-G 421 + L R+ VMEY GG L+ H+ ED R ++VSAL + H++ Sbjct: 210 LTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKN 269 Query: 422 VYHRDIKPDNLLVDEHGNLK 481 V +RD+K +NL++D+ G++K Sbjct: 270 VVYRDLKLENLMLDKDGHIK 289
>AKT1_HUMAN (P31749) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) (C-AKT) Length = 480 Score = 88.6 bits (218), Expect = 8e-18 Identities = 48/140 (34%), Positives = 76/140 (54%), Gaps = 1/140 (0%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 +E +KLLG+G F KV L + T A+K++ KE ++ V E V++ RHP Sbjct: 150 FEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPF 209 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQ-G 421 + L R+ VMEY GG L+ H+ ED R ++VSAL + H++ Sbjct: 210 LTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKN 269 Query: 422 VYHRDIKPDNLLVDEHGNLK 481 V +RD+K +NL++D+ G++K Sbjct: 270 VVYRDLKLENLMLDKDGHIK 289
>CDC2_RAT (P39951) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 88.6 bits (218), Expect = 8e-18 Identities = 47/141 (33%), Positives = 78/141 (55%), Gaps = 2/141 (1%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 Y +++ +GEG + VY RH T + VA+K + E + G REI++++ LRHPN Sbjct: 4 YIKIEKIGEGTYGVVYKGRHRTTGQIVAMKKIRLESEEE-GVPSTAIREISLLKELRHPN 62 Query: 245 IVQLHKVMACKSRIFVVMEYVRGG--PLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQ 418 IV L V+ SR++++ E++ IP + + Q++ + FCH++ Sbjct: 63 IVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQFMDSSLVKSYLYQILQGIVFCHSR 122 Query: 419 GVYHRDIKPDNLLVDEHGNLK 481 V HRD+KP NLL+D+ G +K Sbjct: 123 RVLHRDLKPQNLLIDDKGTIK 143
>AKT_MLVAT (P31748) AKT kinase transforming protein (EC 2.7.11.1)| Length = 501 Score = 88.6 bits (218), Expect = 8e-18 Identities = 48/140 (34%), Positives = 76/140 (54%), Gaps = 1/140 (0%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 +E +KLLG+G F KV L + T A+K++ KE ++ V E V++ RHP Sbjct: 171 FEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPF 230 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQ-G 421 + L R+ VMEY GG L+ H+ ED R ++VSAL + H++ Sbjct: 231 LTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKN 290 Query: 422 VYHRDIKPDNLLVDEHGNLK 481 V +RD+K +NL++D+ G++K Sbjct: 291 VVYRDLKLENLMLDKDGHIK 310
>KCC1D_MOUSE (Q8BW96) Calcium/calmodulin-dependent protein kinase type 1D (EC| 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) (mCKLiK) Length = 385 Score = 88.6 bits (218), Expect = 8e-18 Identities = 46/131 (35%), Positives = 76/131 (58%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 +E + LG G F++V LA T + A+K + K+ L G I+ EIAV+R+++H N Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKAL--KGKESSIENEIAVLRKIKHEN 80 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 IV L + + +++VM+ V GG L+ I G E + + +Q++ A+ + H G+ Sbjct: 81 IVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGI 140 Query: 425 YHRDIKPDNLL 457 HRD+KP+NLL Sbjct: 141 VHRDLKPENLL 151
>KCC1D_HUMAN (Q8IU85) Calcium/calmodulin-dependent protein kinase type 1D (EC| 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) Length = 385 Score = 88.6 bits (218), Expect = 8e-18 Identities = 46/131 (35%), Positives = 76/131 (58%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 +E + LG G F++V LA T + A+K + K+ L G I+ EIAV+R+++H N Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKAL--KGKESSIENEIAVLRKIKHEN 80 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 IV L + + +++VM+ V GG L+ I G E + + +Q++ A+ + H G+ Sbjct: 81 IVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGI 140 Query: 425 YHRDIKPDNLL 457 HRD+KP+NLL Sbjct: 141 VHRDLKPENLL 151
>KPCE_RAT (P09216) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 737 Score = 88.6 bits (218), Expect = 8e-18 Identities = 55/159 (34%), Positives = 85/159 (53%), Gaps = 4/159 (2%) Frame = +2 Query: 17 ESGDGAMGDRPKLPA-RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIK---L 184 E+G+ G +L + +K+LG+G+F KV LA E A+KV+ K+ +++ + Sbjct: 391 ENGEVRQGQAKRLGLDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDV 450 Query: 185 GAVQQIKREIAVMRRLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDE 364 KR +A+ R+ HP + QL+ K R+F VMEYV GG L I + E Sbjct: 451 DCTMTEKRILALARK--HPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPR 508 Query: 365 TRRIFQQLVSALTFCHAQGVYHRDIKPDNLLVDEHGNLK 481 + ++ SAL F H GV +RD+K DN+L+D G+ K Sbjct: 509 SGFYAAEVTSALMFLHQHGVIYRDLKLDNILLDAEGHSK 547
>CDKL1_BRARE (Q6AXJ9) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| Length = 350 Score = 88.6 bits (218), Expect = 8e-18 Identities = 49/143 (34%), Positives = 82/143 (57%), Gaps = 3/143 (2%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVM---DKEKLIKLGAVQQIKREIAVMRRL 232 +YE++ +GEG++ V+ R+ DT + VAIK + + +IK A+ REI ++++L Sbjct: 3 KYEKISKIGEGSYGVVFKCRNKDTGQIVAIKKFVESEDDPIIKKIAL----REIRMLKQL 58 Query: 233 RHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCH 412 +HPN+V L +V K ++ +V EY L G+ E + I Q + A+ FCH Sbjct: 59 KHPNLVNLMEVFRRKRKLHLVFEYCDHTVLNELDRYPRGVPEHMVKSIIWQTLQAVNFCH 118 Query: 413 AQGVYHRDIKPDNLLVDEHGNLK 481 Q HRD+KP+N+L+ +H +K Sbjct: 119 KQNCIHRDVKPENILITKHQVIK 141
>CDKL1_HUMAN (Q00532) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIALRE) (Protein kinase p42 KKIALRE) Length = 357 Score = 88.2 bits (217), Expect = 1e-17 Identities = 49/143 (34%), Positives = 82/143 (57%), Gaps = 3/143 (2%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVM---DKEKLIKLGAVQQIKREIAVMRRL 232 +YE++ +GEG++ V+ R+ DT + VAIK + + +IK A+ REI ++++L Sbjct: 3 KYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIAL----REIRMLKQL 58 Query: 233 RHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCH 412 +HPN+V L +V K R+ +V EY L+ G+ E + I Q + A+ FCH Sbjct: 59 KHPNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCH 118 Query: 413 AQGVYHRDIKPDNLLVDEHGNLK 481 HRD+KP+N+L+ +H +K Sbjct: 119 KHNCIHRDVKPENILITKHSVIK 141
>PKNB_LACLA (Q9CEF5) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 627 Score = 88.2 bits (217), Expect = 1e-17 Identities = 51/141 (36%), Positives = 75/141 (53%), Gaps = 1/141 (0%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEE-VAIKVMDKEKLIKLGAVQQIKREIAVMRRLRH 238 RY +K +G G A VY + VAIKV+ A+ + +RE M L H Sbjct: 11 RYRIIKEIGRGGMANVYQGEDTFLGDRLVAIKVLRSNFENDDIAIARFQREAFAMAELSH 70 Query: 239 PNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQ 418 PNIV + V +S+ ++VME+V G L ++I N L DE I +++SA+ H+ Sbjct: 71 PNIVGISDVGEFESQQYIVMEFVDGMTLKQYINQNAPLANDEAIEIITEILSAMDMAHSH 130 Query: 419 GVYHRDIKPDNLLVDEHGNLK 481 G+ HRD+KP N+LV G +K Sbjct: 131 GIIHRDLKPQNVLVSSSGTVK 151
>KCC1A_RAT (Q63450) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 374 Score = 88.2 bits (217), Expect = 1e-17 Identities = 47/131 (35%), Positives = 77/131 (58%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 Y+ +LG G F++V LA T++ VAIK + K+ L G ++ EIAV+ +++HPN Sbjct: 20 YDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKKALE--GKEGSMENEIAVLHKIKHPN 77 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 IV L + ++++M+ V GG L+ I G E + R+ Q++ A+ + H G+ Sbjct: 78 IVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGI 137 Query: 425 YHRDIKPDNLL 457 HRD+KP+NLL Sbjct: 138 VHRDLKPENLL 148
>KCC1A_MOUSE (Q91YS8) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 374 Score = 88.2 bits (217), Expect = 1e-17 Identities = 47/131 (35%), Positives = 77/131 (58%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 Y+ +LG G F++V LA T++ VAIK + K+ L G ++ EIAV+ +++HPN Sbjct: 20 YDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKKALE--GKEGSMENEIAVLHKIKHPN 77 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 IV L + ++++M+ V GG L+ I G E + R+ Q++ A+ + H G+ Sbjct: 78 IVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGI 137 Query: 425 YHRDIKPDNLL 457 HRD+KP+NLL Sbjct: 138 VHRDLKPENLL 148
>CDC2_PONPY (Q5RCH1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 88.2 bits (217), Expect = 1e-17 Identities = 46/141 (32%), Positives = 77/141 (54%), Gaps = 2/141 (1%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 Y +++ +GEG + VY RH T + V +K + E + G REI++++ LRHPN Sbjct: 4 YTKIEKIGEGTYGVVYKGRHKTTGQVVTMKKIRLESEEE-GVPSTAIREISLLKELRHPN 62 Query: 245 IVQLHKVMACKSRIFVVMEYVRGG--PLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQ 418 IV L V+ SR++++ E++ IP + + Q++ + FCH++ Sbjct: 63 IVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSR 122 Query: 419 GVYHRDIKPDNLLVDEHGNLK 481 V HRD+KP NLL+D+ G +K Sbjct: 123 RVLHRDLKPQNLLIDDKGTIK 143
>CDC2_MOUSE (P11440) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 88.2 bits (217), Expect = 1e-17 Identities = 47/141 (33%), Positives = 78/141 (55%), Gaps = 2/141 (1%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 Y +++ +GEG + VY RH T + VA+K + E + G REI++++ LRHPN Sbjct: 4 YIKIEKIGEGTYGVVYKGRHRVTGQIVAMKKIRLESEEE-GVPSTAIREISLLKELRHPN 62 Query: 245 IVQLHKVMACKSRIFVVMEYVRGG--PLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQ 418 IV L V+ SR++++ E++ IP + + Q++ + FCH++ Sbjct: 63 IVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQFMDSSLVKSYLHQILQGIVFCHSR 122 Query: 419 GVYHRDIKPDNLLVDEHGNLK 481 V HRD+KP NLL+D+ G +K Sbjct: 123 RVLHRDLKPQNLLIDDKGTIK 143
>AKT1_XENLA (Q98TY9) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase Akt-1) (Protein kinase B, alpha) (PKB alpha) (xAkt) Length = 481 Score = 88.2 bits (217), Expect = 1e-17 Identities = 48/140 (34%), Positives = 76/140 (54%), Gaps = 1/140 (0%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 +E +KLLG+G F KV L + T A+K++ KE ++ V E V++ RHP Sbjct: 151 FEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPF 210 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQ-G 421 + L R+ VMEY GG L+ H+ ED R ++VSAL + H++ Sbjct: 211 LTALKYSFQTHDRLCFVMEYANGGELFFHLSRERIFSEDRARFYGAEIVSALDYLHSEKN 270 Query: 422 VYHRDIKPDNLLVDEHGNLK 481 V +RD+K +NL++D+ G++K Sbjct: 271 VVYRDLKLENLMLDKDGHIK 290
>SRK1_SCHPO (O94547) Serine/threonine-protein kinase srk1 (EC 2.7.11.1)| (Sty1-regulated kinase 1) Length = 580 Score = 88.2 bits (217), Expect = 1e-17 Identities = 53/144 (36%), Positives = 80/144 (55%), Gaps = 10/144 (6%) Frame = +2 Query: 62 RYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVM-------DKEKLIKLGAVQQ--IKREI 214 +Y ++ +G+G F+ VY A H T E+VAIKV+ D K V+ I +E+ Sbjct: 123 QYTLLQKMGDGAFSNVYKAIHNRTGEKVAIKVVQRAQPNTDPRDPRKRQGVESHNILKEV 182 Query: 215 AVMRRLRHPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVS 394 +MRR++HPNI+QL + + ++V+E GG L+ I ED +R + Q+ Sbjct: 183 QIMRRVKHPNIIQLLEFIQTPEYYYLVLELADGGELFHQIVRLTYFSEDLSRHVITQVAH 242 Query: 395 ALTFCHAQ-GVYHRDIKPDNLLVD 463 A+ + H GV HRDIKP+NLL D Sbjct: 243 AIRYLHEDCGVVHRDIKPENLLFD 266
>PHO85_YARLI (Q6C7U8) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 294 Score = 88.2 bits (217), Expect = 1e-17 Identities = 50/144 (34%), Positives = 86/144 (59%), Gaps = 3/144 (2%) Frame = +2 Query: 59 ARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRH 238 ++++Q++ LGEG +A VY R+ T + VA+K ++ + + G REI++M+ L+H Sbjct: 5 SQFQQLEKLGEGTYATVYKGRNRTTGQLVALKEINLDS--EEGTPSTAIREISLMKELKH 62 Query: 239 PNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRI---FQQLVSALTFC 409 NIV L+ V+ ++++ +V EY+ L + + NG ET+++ QL+ + FC Sbjct: 63 ENIVTLYDVIHTENKLNLVFEYM-DKDLKKFMDTNGNKGALETKQVKWFMYQLLRGILFC 121 Query: 410 HAQGVYHRDIKPDNLLVDEHGNLK 481 H V HRD+KP NLL++ G LK Sbjct: 122 HDNRVLHRDLKPQNLLINAKGQLK 145
>KAD5_SCHPO (Q09831) Probable serine/threonine-protein kinase C4G8.05 (EC| 2.7.11.1) Length = 566 Score = 88.2 bits (217), Expect = 1e-17 Identities = 45/143 (31%), Positives = 81/143 (56%), Gaps = 2/143 (1%) Frame = +2 Query: 56 PARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLR 235 P+ +E+V LLG+G+ +VYL R + + A+KV+ K+++IK ++ E ++ Sbjct: 192 PSSFEKVFLLGKGDVGRVYLVREKKSGKFYAMKVLSKQEMIKRNKSKRAFAEQHILATSN 251 Query: 236 HPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGG--LKEDETRRIFQQLVSALTFC 409 HP IV L+ +++ MEY GG +R + G L E+E + ++ +AL + Sbjct: 252 HPFIVTLYHSFQSDEYLYLCMEYCMGGEFFRALQRRPGRCLSENEAKFYIAEVTAALEYL 311 Query: 410 HAQGVYHRDIKPDNLLVDEHGNL 478 H G +RD+KP+N+L+ E G++ Sbjct: 312 HLMGFIYRDLKPENILLHESGHI 334
>KPCI_BRARE (Q90XF2) Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota)| (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (Heart and soul protein) Length = 588 Score = 87.8 bits (216), Expect = 1e-17 Identities = 47/140 (33%), Positives = 80/140 (57%), Gaps = 1/140 (0%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRL-RHP 241 ++ ++++G G++AKV L R T+ A+KV+ KE + + ++ E V + HP Sbjct: 246 FDLLRVIGRGSYAKVLLVRLKKTERIYAMKVVKKELVNDDEDIDWVQTEKHVFEQASNHP 305 Query: 242 NIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQG 421 +V LH +SR+F V+EYV GG L H+ L E+ R ++ AL + H +G Sbjct: 306 FLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHERG 365 Query: 422 VYHRDIKPDNLLVDEHGNLK 481 + +RD+K DN+L+D G++K Sbjct: 366 IIYRDLKLDNVLLDSEGHIK 385
>TSSK2_HUMAN (Q96PF2) Testis-specific serine/threonine-protein kinase 2 (EC| 2.7.11.1) (TSSK-2) (Testis-specific kinase 2) (TSK-2) (Serine/threonine-protein kinase 22B) (DiGeorge syndrome protein G) Length = 358 Score = 87.8 bits (216), Expect = 1e-17 Identities = 46/134 (34%), Positives = 80/134 (59%), Gaps = 1/134 (0%) Frame = +2 Query: 83 LGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPNIVQLHK 262 LG+G++AKV A K VA+K++D++K + + RE+ ++ + H +I++ ++ Sbjct: 18 LGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNHGSIIKTYE 77 Query: 263 VMACKS-RIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGVYHRDI 439 + RI+++ME G L I G L ED R++F+QL SA+ +CH + HRD+ Sbjct: 78 IFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQLSSAVKYCHDLDIVHRDL 137 Query: 440 KPDNLLVDEHGNLK 481 K +NLL+D+ N+K Sbjct: 138 KCENLLLDKDFNIK 151
>KAPC_ASCSU (P49673) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) (PKA C) Length = 337 Score = 87.8 bits (216), Expect = 1e-17 Identities = 38/139 (27%), Positives = 84/139 (60%) Frame = +2 Query: 65 YEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKLGAVQQIKREIAVMRRLRHPN 244 ++++ +G G+F +VYL +H +++ A+K M +++ + + + E ++ RL HP Sbjct: 29 FDRICTIGTGSFGRVYLVQHRASEQYFALKKMAIREVVSMRQTEHVHSEKRLLSRLSHPF 88 Query: 245 IVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKEDETRRIFQQLVSALTFCHAQGV 424 IV+++ K ++++ EY+ GG L+ ++ A+ R ++V AL + H++ + Sbjct: 89 IVKMYCASWDKYNLYMLFEYLAGGELFSYLRASRTFSNSMARFYAAEIVCALQYLHSKNI 148 Query: 425 YHRDIKPDNLLVDEHGNLK 481 +RD+KP+NL++++ G+LK Sbjct: 149 AYRDLKPENLMLNKEGHLK 167
>CDPK2_MAIZE (P49101) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (CDPK 2)| Length = 513 Score = 87.8 bits (216), Expect = 1e-17 Identities = 55/163 (33%), Positives = 83/163 (50%), Gaps = 5/163 (3%) Frame = +2 Query: 8 PAQESGDGAMGDRPK-LPARYEQVKLLGEGNFAKVYLARHMDTKEEVAIKVMDKEKLIKL 184 P + + D +G + + + + Y K LG G F YL + + + A K + K KL+ Sbjct: 45 PPKPTADTILGKQYEDVRSVYSFGKELGRGQFGVTYLCTEIASGRQYACKSISKRKLVSK 104 Query: 185 GAVQQIKREIAVMRRLR-HPNIVQLHKVMACKSRIFVVMEYVRGGPLYRHIPANGGLKED 361 + I+REI +M+ L PNIV+ KS + VVME GG L+ I A G E Sbjct: 105 ADREDIRREIQIMQHLSGQPNIVEFRGAYEDKSNVHVVMELCAGGELFDRIIAKGHYTER 164 Query: 362 ETRRIFQQLVSALTFCHAQGVYHRDIKPDNLL---VDEHGNLK 481 I + +V+ + CH GV HRD+KP+N L ++E+ LK Sbjct: 165 AAATICRAVVNVVNICHFMGVMHRDLKPENFLLATMEENAMLK 207 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 53,049,065 Number of Sequences: 219361 Number of extensions: 934086 Number of successful extensions: 7728 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 5767 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6110 length of database: 80,573,946 effective HSP length: 103 effective length of database: 57,979,763 effective search space used: 3304846491 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
