ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | baal16m01 |
|---|---|
| Clone Library Name | barley_pub |
>PBS1_ARATH (Q9FE20) Serine/threonine-protein kinase PBS1 (EC 2.7.11.1)| (AvrPphB susceptible protein 1) Length = 456 Score = 94.0 bits (232), Expect = 2e-19 Identities = 55/132 (41%), Positives = 75/132 (56%) Frame = +1 Query: 76 DGNCLQVARKFSYSELVAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTL 255 DG A F++ EL AAT NF D +G+G FG VY+G L + VAVK++ + L Sbjct: 64 DGLGQIAAHTFAFRELAAATMNFHPDTFLGEGGFGRVYKGRLDSTG-QVVAVKQLDRNGL 122 Query: 256 KRNRKNYVHEIETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRT 435 + NR+ ++ E+ L L H NL+ LIG+C DG + +L+YE P GS+ DHLHD Sbjct: 123 QGNRE-FLVEVLMLSLLHHPNLVNLIGYCADGDQRLLVYEFMPLGSLEDHLHDLPPDKEA 181 Query: 436 LTWPQRYNILLG 471 L W R I G Sbjct: 182 LDWNMRMKIAAG 193
>CRI4_MAIZE (O24585) Putative receptor protein kinase CRINKLY4 precursor (EC| 2.7.11.1) Length = 901 Score = 90.9 bits (224), Expect = 2e-18 Identities = 49/124 (39%), Positives = 77/124 (62%), Gaps = 2/124 (1%) Frame = +1 Query: 97 ARKFSYSELVAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKE-MRQPTLKRNRKN 273 A++FSY EL AT FS D ++GKGSF V++G+L D VAVK ++ +K++ K Sbjct: 490 AQEFSYEELEQATGGFSEDSQVGKGSFSCVFKGILR--DGTVVAVKRAIKASDVKKSSKE 547 Query: 274 YVHEIETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGAS-GRTLTWPQ 450 + +E++ L +L H +LL L+G+C+DG +L+YE +GS+ HLH + + L W + Sbjct: 548 FHNELDLLSRLNHAHLLNLLGYCEDGSERLLVYEFMAHGSLYQHLHGKDPNLKKRLNWAR 607 Query: 451 RYNI 462 R I Sbjct: 608 RVTI 611
>BRI1_ARATH (O22476) BRASSINOSTEROID INSENSITIVE 1 precursor (EC 2.7.11.1)| (AtBRI1) (Brassinosteroid LRR receptor kinase) Length = 1196 Score = 89.0 bits (219), Expect = 6e-18 Identities = 46/124 (37%), Positives = 77/124 (62%) Frame = +1 Query: 100 RKFSYSELVAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYV 279 RK ++++L+ AT+ F D IG G FGDVY+ +L D VA+K++ + + +R+ ++ Sbjct: 869 RKLTFADLLQATNGFHNDSLIGSGGFGDVYKAILK--DGSAVAIKKLIHVSGQGDRE-FM 925 Query: 280 HEIETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTLTWPQRYN 459 E+ET+ +++H+NL+ L+G+C G +L+YE GS+ D LHD +G L W R Sbjct: 926 AEMETIGKIKHRNLVPLLGYCKVGDERLLVYEFMKYGSLEDVLHDPKKAGVKLNWSTRRK 985 Query: 460 ILLG 471 I +G Sbjct: 986 IAIG 989
>BRI1_LYCPE (Q8L899) Systemin receptor SR160 precursor (EC 2.7.11.1)| (Brassinosteroid LRR receptor kinase) Length = 1207 Score = 88.6 bits (218), Expect = 8e-18 Identities = 46/124 (37%), Positives = 76/124 (61%) Frame = +1 Query: 100 RKFSYSELVAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYV 279 RK ++++L+ AT+ F D +G G FGDVY+ L D VA+K++ + + +R+ + Sbjct: 874 RKLTFADLLEATNGFHNDSLVGSGGFGDVYKAQLK--DGSVVAIKKLIHVSGQGDRE-FT 930 Query: 280 HEIETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTLTWPQRYN 459 E+ET+ +++H+NL+ L+G+C G +L+YE GS+ D LHD +G L WP R Sbjct: 931 AEMETIGKIKHRNLVPLLGYCKVGEERLLVYEYMKYGSLEDVLHDRKKTGIKLNWPARRK 990 Query: 460 ILLG 471 I +G Sbjct: 991 IAIG 994
>BRI1_LYCES (Q8GUQ5) Brassinosteroid LRR receptor kinase precursor (EC 2.7.11.1)| (tBRI1) (Altered brassinolide sensitivity 1) (Systemin receptor SR160) Length = 1207 Score = 87.4 bits (215), Expect = 2e-17 Identities = 46/124 (37%), Positives = 75/124 (60%) Frame = +1 Query: 100 RKFSYSELVAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYV 279 RK ++++L+ AT+ F D +G G FGDVY+ L D VA+K++ + + +R+ + Sbjct: 874 RKLTFADLLEATNGFHNDSLVGSGGFGDVYKAQLK--DGSVVAIKKLIHVSGQGDRE-FT 930 Query: 280 HEIETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTLTWPQRYN 459 E+ET+ +++H+NL+ L+G+C G +L+YE GS+ D LHD G L WP R Sbjct: 931 AEMETIGKIKHRNLVPLLGYCKVGEERLLVYEYMKYGSLEDVLHDRKKIGIKLNWPARRK 990 Query: 460 ILLG 471 I +G Sbjct: 991 IAIG 994
>RLCK7_ARATH (Q9LQQ8) Probable serine/threonine-protein kinase RLCKVII (EC| 2.7.11.1) Length = 423 Score = 85.5 bits (210), Expect = 6e-17 Identities = 47/125 (37%), Positives = 75/125 (60%) Frame = +1 Query: 97 ARKFSYSELVAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNY 276 A+ F++ EL AT NF D +G+G FG V++G + D + VA+K++ + ++ R+ + Sbjct: 88 AQTFTFQELAEATGNFRSDCFLGEGGFGKVFKGTIEKLD-QVVAIKQLDRNGVQGIRE-F 145 Query: 277 VHEIETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTLTWPQRY 456 V E+ TL H NL++LIG+C +G + +L+YE P GS+ DHLH + + L W R Sbjct: 146 VVEVLTLSLADHPNLVKLIGFCAEGDQRLLVYEYMPQGSLEDHLHVLPSGKKPLDWNTRM 205 Query: 457 NILLG 471 I G Sbjct: 206 KIAAG 210
>IRAK1_HUMAN (P51617) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) Length = 712 Score = 85.1 bits (209), Expect = 8e-17 Identities = 48/132 (36%), Positives = 70/132 (53%), Gaps = 4/132 (3%) Frame = +1 Query: 88 LQVARKFSYS----ELVAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTL 255 LQ AR F + E+ T NFS + KIG+G FG VYR ++ +KE Sbjct: 190 LQGARPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEW 249 Query: 256 KRNRKNYVHEIETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRT 435 +++++ E+E L + RH N++ G+C G L+Y PNGS+ D LH + Sbjct: 250 TAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPP 309 Query: 436 LTWPQRYNILLG 471 L+WPQR +ILLG Sbjct: 310 LSWPQRLDILLG 321
>IRAK1_MOUSE (Q62406) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK) Length = 710 Score = 83.6 bits (205), Expect = 2e-16 Identities = 42/120 (35%), Positives = 66/120 (55%) Frame = +1 Query: 112 YSELVAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIE 291 + E+ T NFS + +IG+G FG VYR ++ +KE +++++ E+E Sbjct: 202 FCEISQGTCNFSEELRIGEGGFGCVYRAVMRNTTYAVKRLKEEADLEWTMVKQSFLTEVE 261 Query: 292 TLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTLTWPQRYNILLG 471 L + RH N++ G+C + G L+Y PNGS+ D LH + L+WPQR +ILLG Sbjct: 262 QLSRFRHPNIVDFAGYCAESGLYCLVYGFLPNGSLEDQLHLQTQACSPLSWPQRLDILLG 321
>BRL3_ARATH (Q9LJF3) Serine/threonine-protein kinase BRI1-like 3 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 3) Length = 1164 Score = 81.6 bits (200), Expect = 9e-16 Identities = 47/125 (37%), Positives = 75/125 (60%), Gaps = 1/125 (0%) Frame = +1 Query: 100 RKFSYSELVAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYV 279 RK +++ L+ AT+ FS D IG G FGDVY+ L D VA+K++ Q T + +R+ ++ Sbjct: 844 RKLTFAHLLEATNGFSADSMIGSGGFGDVYKAKLA--DGSVVAIKKLIQVTGQGDRE-FM 900 Query: 280 HEIETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRT-LTWPQRY 456 E+ET+ +++H+NL+ L+G+C G +L+YE GS+ LH+ G L W R Sbjct: 901 AEMETIGKIKHRNLVPLLGYCKIGEERLLVYEYMKYGSLETVLHEKTKKGGIFLDWSARK 960 Query: 457 NILLG 471 I +G Sbjct: 961 KIAIG 965
>BAK1_ARATH (Q94F62) BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1| precursor (EC 2.7.11.1) (BRI1-associated receptor kinase 1) (Somatic embryogenesis receptor-like kinase 3) Length = 615 Score = 80.9 bits (198), Expect = 2e-15 Identities = 46/124 (37%), Positives = 67/124 (54%) Frame = +1 Query: 100 RKFSYSELVAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYV 279 ++FS EL A+DNFS +G+G FG VY+G L L VAVK +++ + + Sbjct: 275 KRFSLRELQVASDNFSNKNILGRGGFGKVYKGRLADGTL--VAVKRLKEERTQGGELQFQ 332 Query: 280 HEIETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTLTWPQRYN 459 E+E + H+NLL+L G+C +L+Y NGSV+ L + S L WP+R Sbjct: 333 TEVEMISMAVHRNLLRLRGFCMTPTERLLVYPYMANGSVASCLRERPESQPPLDWPKRQR 392 Query: 460 ILLG 471 I LG Sbjct: 393 IALG 396
>APK1A_ARATH (Q06548) Protein kinase APK1A, chloroplast precursor (EC 2.7.11.1)| Length = 410 Score = 80.5 bits (197), Expect = 2e-15 Identities = 48/148 (32%), Positives = 82/148 (55%), Gaps = 10/148 (6%) Frame = +1 Query: 58 RPTRCLDGNCLQVA--RKFSYSELVAATDNFSRDRKIGKGSFGDVYRGLLPMPDLRE--- 222 RP+ +G LQ + FS++EL +AT NF D +G+G FG V++G + L Sbjct: 38 RPSPRTEGEILQSPNLKSFSFAELKSATRNFRPDSVLGEGGFGCVFKGWIDEKSLTASRP 97 Query: 223 -----VAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPN 387 +AVK++ Q + +++ ++ E+ L Q H++L++LIG+C + +L+YE P Sbjct: 98 GTGLVIAVKKLNQDGWQGHQE-WLAEVNYLGQFSHRHLVKLIGYCLEDEHRLLVYEFMPR 156 Query: 388 GSVSDHLHDGGASGRTLTWPQRYNILLG 471 GS+ +HL G + L+W R + LG Sbjct: 157 GSLENHLFRRGLYFQPLSWKLRLKVALG 184
>APK1B_ARATH (P46573) Protein kinase APK1B, chloroplast precursor (EC 2.7.11.1)| Length = 412 Score = 80.1 bits (196), Expect = 3e-15 Identities = 44/132 (33%), Positives = 75/132 (56%), Gaps = 8/132 (6%) Frame = +1 Query: 100 RKFSYSELVAATDNFSRDRKIGKGSFGDVYRGLLPMPDLRE--------VAVKEMRQPTL 255 + F+++EL AAT NF D +G+G FG V++G + L +AVK++ Q Sbjct: 55 KSFTFAELKAATRNFRPDSVLGEGGFGSVFKGWIDEQTLTASKPGTGVVIAVKKLNQDGW 114 Query: 256 KRNRKNYVHEIETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRT 435 + +++ ++ E+ L Q H NL++LIG+C + +L+YE P GS+ +HL G+ + Sbjct: 115 QGHQE-WLAEVNYLGQFSHPNLVKLIGYCLEDEHRLLVYEFMPRGSLENHLFRRGSYFQP 173 Query: 436 LTWPQRYNILLG 471 L+W R + LG Sbjct: 174 LSWTLRLKVALG 185
>NAK_ARATH (P43293) Probable serine/threonine-protein kinase NAK (EC 2.7.11.1)| Length = 389 Score = 79.7 bits (195), Expect = 3e-15 Identities = 51/142 (35%), Positives = 77/142 (54%), Gaps = 10/142 (7%) Frame = +1 Query: 76 DGNCLQVA--RKFSYSELVAATDNFSRDRKIGKGSFGDVYRGLLPMPDLRE--------V 225 +G LQ A + FS SEL +AT NF D +G+G FG V++G + L + Sbjct: 44 EGEILQNANLKNFSLSELKSATRNFRPDSVVGEGGFGCVFKGWIDESSLAPSKPGTGIVI 103 Query: 226 AVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDH 405 AVK + Q + +R+ ++ EI L QL H NL++LIG+C + +L+YE GS+ +H Sbjct: 104 AVKRLNQEGFQGHRE-WLAEINYLGQLDHPNLVKLIGYCLEEEHRLLVYEFMTRGSLENH 162 Query: 406 LHDGGASGRTLTWPQRYNILLG 471 L G + L+W R + LG Sbjct: 163 LFRRGTFYQPLSWNTRVRMALG 184
>SIRK_ARATH (O64483) Senescence-induced receptor-like serine/threonine-protein| kinase precursor (FLG22-induced receptor-like kinase 1) Length = 876 Score = 79.3 bits (194), Expect = 5e-15 Identities = 54/159 (33%), Positives = 87/159 (54%), Gaps = 6/159 (3%) Frame = +1 Query: 10 GLLVALLSLI--YTTFIKRPTRCL----DGNCLQVARKFSYSELVAATDNFSRDRKIGKG 171 G++V LL+ + + F K+ R +G R F YSE+V T+NF +R IGKG Sbjct: 526 GIIVVLLTALALFRRFKKKQQRGTLGERNGPLKTAKRYFKYSEVVNITNNF--ERVIGKG 583 Query: 172 SFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLIGWCDDG 351 FG VY G++ + +VAVK + + + + K + E++ L ++ H NL L+G+C++ Sbjct: 584 GFGKVYHGVI---NGEQVAVKVLSEESAQ-GYKEFRAEVDLLMRVHHTNLTSLVGYCNEI 639 Query: 352 GRLVLIYELEPNGSVSDHLHDGGASGRTLTWPQRYNILL 468 +VLIYE N ++ D+L G L+W +R I L Sbjct: 640 NHMVLIYEYMANENLGDYL--AGKRSFILSWEERLKISL 676
>EXS_ARATH (Q9LYN8) Leucine-rich repeat receptor protein kinase EXS precursor| (EC 2.7.11.1) (Extra sporogenous cells protein) (EXCESS MICROSPOROCYTES1 protein) Length = 1192 Score = 79.0 bits (193), Expect = 6e-15 Identities = 44/123 (35%), Positives = 70/123 (56%) Frame = +1 Query: 103 KFSYSELVAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVH 282 K ++V ATD+FS+ IG G FG VY+ LP + VAVK++ + + NR+ ++ Sbjct: 904 KVRLGDIVEATDHFSKKNIIGDGGFGTVYKACLPGE--KTVAVKKLSEAKTQGNRE-FMA 960 Query: 283 EIETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTLTWPQRYNI 462 E+ETL +++H NL+ L+G+C +L+YE NGS+ L + L W +R I Sbjct: 961 EMETLGKVKHPNLVSLLGYCSFSEEKLLVYEYMVNGSLDHWLRNQTGMLEVLDWSKRLKI 1020 Query: 463 LLG 471 +G Sbjct: 1021 AVG 1023
>TMK1_ARATH (P43298) Putative receptor protein kinase TMK1 precursor (EC| 2.7.11.1) Length = 942 Score = 79.0 bits (193), Expect = 6e-15 Identities = 45/124 (36%), Positives = 69/124 (55%), Gaps = 2/124 (1%) Frame = +1 Query: 109 SYSELVAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLK-RNRKNYVHE 285 S L + T+NFS D +G G FG VY+G L D ++AVK M + + + E Sbjct: 577 SIQVLRSVTNNFSSDNILGSGGFGVVYKGELH--DGTKIAVKRMENGVIAGKGFAEFKSE 634 Query: 286 IETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGASG-RTLTWPQRYNI 462 I L ++RH++L+ L+G+C DG +L+YE P G++S HL + G + L W QR + Sbjct: 635 IAVLTKVRHRHLVTLLGYCLDGNEKLLVYEYMPQGTLSRHLFEWSEEGLKPLLWKQRLTL 694 Query: 463 LLGI 474 L + Sbjct: 695 ALDV 698
>BRL2_ARATH (Q9ZPS9) Serine/threonine-protein kinase BRI1-like 2 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 2) (Protein VASCULAR HIGHWAY 1) Length = 1143 Score = 79.0 bits (193), Expect = 6e-15 Identities = 45/126 (35%), Positives = 75/126 (59%), Gaps = 2/126 (1%) Frame = +1 Query: 100 RKFSYSELVAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYV 279 RK +S+L+ AT+ FS IG G FG+V++ L D VA+K++ + + + +R+ ++ Sbjct: 824 RKLKFSQLIEATNGFSAASMIGHGGFGEVFKATLK--DGSSVAIKKLIRLSCQGDRE-FM 880 Query: 280 HEIETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHD--GGASGRTLTWPQR 453 E+ETL +++H+NL+ L+G+C G +L+YE GS+ + LH G R L W +R Sbjct: 881 AEMETLGKIKHRNLVPLLGYCKIGEERLLVYEFMQYGSLEEVLHGPRTGEKRRILGWEER 940 Query: 454 YNILLG 471 I G Sbjct: 941 KKIAKG 946
>NORK_PEA (Q8LKZ1) Nodulation receptor kinase precursor (EC 2.7.11.1)| Length = 924 Score = 78.6 bits (192), Expect = 8e-15 Identities = 44/124 (35%), Positives = 72/124 (58%) Frame = +1 Query: 100 RKFSYSELVAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYV 279 + F+ + AT+ + IG+G FG VYRG L D +EVAVK +R T + + + Sbjct: 583 KPFTLEYIELATEKYKT--LIGEGGFGSVYRGTLD--DGQEVAVK-VRSATSTQGTREFD 637 Query: 280 HEIETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTLTWPQRYN 459 +E+ L ++H+NL+ L+G+C++ + +L+Y NGS+ D L+ A + L WP R + Sbjct: 638 NELNLLSAIQHENLVPLLGYCNEYDQQILVYPFMSNGSLLDRLYGEPAKRKILDWPTRLS 697 Query: 460 ILLG 471 I LG Sbjct: 698 IALG 701
>NORK_MEDTR (Q8L4H4) Nodulation receptor kinase precursor (EC 2.7.11.1) (Does| not make infections protein 2) (Symbiosis receptor-like kinase) (MtSYMRK) Length = 925 Score = 78.2 bits (191), Expect = 1e-14 Identities = 43/124 (34%), Positives = 72/124 (58%) Frame = +1 Query: 100 RKFSYSELVAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYV 279 + F+ + AT+ + IG+G FG VYRG L D +EVAVK +R T + + + Sbjct: 584 KPFTLEYIEQATEQYKT--LIGEGGFGSVYRGTLD--DGQEVAVK-VRSSTSTQGTREFD 638 Query: 280 HEIETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTLTWPQRYN 459 +E+ L ++H+NL+ L+G+C++ + +L+Y NGS+ D L+ + + L WP R + Sbjct: 639 NELNLLSAIQHENLVPLLGYCNEYDQQILVYPFMSNGSLLDRLYGEASKRKILDWPTRLS 698 Query: 460 ILLG 471 I LG Sbjct: 699 IALG 702
>KPEL_DROME (Q05652) Probable serine/threonine-protein kinase pelle (EC| 2.7.11.1) Length = 501 Score = 77.4 bits (189), Expect = 2e-14 Identities = 46/128 (35%), Positives = 69/128 (53%), Gaps = 5/128 (3%) Frame = +1 Query: 103 KFSYSELVAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNR---KN 273 + Y+EL ATD +S D ++G+G FGDVYRG D+ + V R P + + + Sbjct: 200 EIDYAELENATDGWSPDNRLGQGGFGDVYRGKWKQLDV-AIKVMNYRSPNIDQKMVELQQ 258 Query: 274 YVHEIETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHL--HDGGASGRTLTWP 447 +E++ L +RH N+L L G+ GG+ L+Y+L GS+ L H LTW Sbjct: 259 SYNELKYLNSIRHDNILALYGYSIKGGKPCLVYQLMKGGSLEARLRAHKAQNPLPALTWQ 318 Query: 448 QRYNILLG 471 QR++I LG Sbjct: 319 QRFSISLG 326
>BRL1_ARATH (Q9ZWC8) Serine/threonine-protein kinase BRI1-like 1 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 1) Length = 1166 Score = 75.9 bits (185), Expect = 5e-14 Identities = 43/126 (34%), Positives = 76/126 (60%), Gaps = 2/126 (1%) Frame = +1 Query: 100 RKFSYSELVAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYV 279 RK +++ L+ AT+ FS + +G G FG+VY+ L D VA+K++ + T + +R+ ++ Sbjct: 845 RKLTFAHLLEATNGFSAETMVGSGGFGEVYKAQLR--DGSVVAIKKLIRITGQGDRE-FM 901 Query: 280 HEIETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGA--SGRTLTWPQR 453 E+ET+ +++H+NL+ L+G+C G +L+YE GS+ LH+ + G L W R Sbjct: 902 AEMETIGKIKHRNLVPLLGYCKVGEERLLVYEYMKWGSLETVLHEKSSKKGGIYLNWAAR 961 Query: 454 YNILLG 471 I +G Sbjct: 962 KKIAIG 967
>SRK6_BRAOE (Q09092) Putative serine/threonine-protein kinase receptor| precursor (EC 2.7.11.1) (S-receptor kinase) (SRK) Length = 849 Score = 74.7 bits (182), Expect = 1e-13 Identities = 42/118 (35%), Positives = 72/118 (61%) Frame = +1 Query: 121 LVAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLC 300 +V AT+NFS K+G+G FG VY+G L D +E+AVK + + +++ +++E+ + Sbjct: 521 VVKATENFSSCNKLGQGGFGIVYKGRLL--DGKEIAVKRLSKTSVQ-GTDEFMNEVTLIA 577 Query: 301 QLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTLTWPQRYNILLGI 474 +L+H NL+Q++G C +G +LIYE N S+ +L G L W +R++I G+ Sbjct: 578 RLQHINLVQVLGCCIEGDEKMLIYEYLENLSLDSYLF-GKTRRSKLNWNERFDITNGV 634
>KPRO_MAIZE (P17801) Putative receptor protein kinase ZmPK1 precursor (EC| 2.7.11.1) Length = 817 Score = 74.7 bits (182), Expect = 1e-13 Identities = 43/125 (34%), Positives = 75/125 (60%) Frame = +1 Query: 100 RKFSYSELVAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYV 279 R++SY ELV AT F + +G+G G VY+G+L D R VAVK++ +++ ++ + Sbjct: 522 RRYSYRELVKATRKFKVE--LGRGESGTVYKGVLE--DDRHVAVKKLEN--VRQGKEVFQ 575 Query: 280 HEIETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTLTWPQRYN 459 E+ + ++ H NL+++ G+C +G +L+ E NGS+++ L G + L W R+N Sbjct: 576 AELSVIGRINHMNLVRIWGFCSEGSHRLLVSEYVENGSLANILFSEGGN-ILLDWEGRFN 634 Query: 460 ILLGI 474 I LG+ Sbjct: 635 IALGV 639
>CX32_ARATH (P27450) Probable serine/threonine-protein kinase Cx32, chloroplast| precursor (EC 2.7.11.1) Length = 419 Score = 69.3 bits (168), Expect = 5e-12 Identities = 47/152 (30%), Positives = 70/152 (46%), Gaps = 7/152 (4%) Frame = +1 Query: 37 IYTTFIKRPTRCLDGNCLQVARKFSYSELVAATDNFSRDRKIGKGSFGDVYRGLLPMPDL 216 I T I + L+ L+V +++ +L AT NF D +G+G FG VYRG + L Sbjct: 54 ISTGIISDSGKLLESPNLKV---YNFLDLKTATKNFKPDSMLGQGGFGKVYRGWVDATTL 110 Query: 217 REVAVKEMRQPTLKRNRKNYVH-------EIETLCQLRHKNLLQLIGWCDDGGRLVLIYE 375 V +KR V E+ L L H+NL++L+G+C + L+L+YE Sbjct: 111 APSRVGSGMIVAIKRLNSESVQGFAEWRSEVNFLGMLSHRNLVKLLGYCREDKELLLVYE 170 Query: 376 LEPNGSVSDHLHDGGASGRTLTWPQRYNILLG 471 P GS+ HL W R I++G Sbjct: 171 FMPKGSLESHLF---RRNDPFPWDLRIKIVIG 199
>PSKR_DAUCA (Q8LPB4) Phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1021 Score = 68.6 bits (166), Expect = 8e-12 Identities = 41/123 (33%), Positives = 68/123 (55%) Frame = +1 Query: 103 KFSYSELVAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVH 282 + S +++ +T +F++ IG G FG VY+ LP D +VA+K + T + +R+ + Sbjct: 730 ELSLDDILKSTSSFNQANIIGCGGFGLVYKATLP--DGTKVAIKRLSGDTGQMDRE-FQA 786 Query: 283 EIETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTLTWPQRYNI 462 E+ETL + +H NL+ L+G+C+ +LIY NGS+ LH+ +L W R I Sbjct: 787 EVETLSRAQHPNLVHLLGYCNYKNDKLLIYSYMDNGSLDYWLHEKVDGPPSLDWKTRLRI 846 Query: 463 LLG 471 G Sbjct: 847 ARG 849
>PSKR_ARATH (Q9ZVR7) Putative phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1008 Score = 67.4 bits (163), Expect = 2e-11 Identities = 42/124 (33%), Positives = 67/124 (54%) Frame = +1 Query: 100 RKFSYSELVAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYV 279 ++ SY +L+ +T++F + IG G FG VY+ LP D ++VA+K++ + R+ + Sbjct: 720 KELSYDDLLDSTNSFDQANIIGCGGFGMVYKATLP--DGKKVAIKKLSGDCGQIERE-FE 776 Query: 280 HEIETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTLTWPQRYN 459 E+ETL + +H NL+ L G+C +LIY NGS+ LH+ L W R Sbjct: 777 AEVETLSRAQHPNLVLLRGFCFYKNDRLLIYSYMENGSLDYWLHERNDGPALLKWKTRLR 836 Query: 460 ILLG 471 I G Sbjct: 837 IAQG 840
>CLV1_ARATH (Q9SYQ8) Receptor protein kinase CLAVATA1 precursor (EC 2.7.11.1)| Length = 980 Score = 67.4 bits (163), Expect = 2e-11 Identities = 37/101 (36%), Positives = 61/101 (60%) Frame = +1 Query: 160 IGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLIGW 339 IGKG G VYRG MP+ +VA+K + R+ + EI+TL ++RH+++++L+G+ Sbjct: 698 IGKGGAGIVYRG--SMPNNVDVAIKRLVGRGTGRSDHGFTAEIQTLGRIRHRHIVRLLGY 755 Query: 340 CDDGGRLVLIYELEPNGSVSDHLHDGGASGRTLTWPQRYNI 462 + +L+YE PNGS+ + LH G+ G L W R+ + Sbjct: 756 VANKDTNLLLYEYMPNGSLGELLH--GSKGGHLQWETRHRV 794
>IRAK4_HUMAN (Q9NWZ3) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) (NY-REN-64 antigen) Length = 460 Score = 65.9 bits (159), Expect = 5e-11 Identities = 42/130 (32%), Positives = 66/130 (50%), Gaps = 8/130 (6%) Frame = +1 Query: 106 FSYSELVAATDNFSR------DRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNR 267 FS+ EL T+NF K+G+G FG VY+G + + + M T + + Sbjct: 168 FSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELK 227 Query: 268 KNYVHEIETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLH--DGGASGRTLT 441 + + EI+ + + +H+NL++L+G+ DG L L+Y PNGS+ D L DG L+ Sbjct: 228 QQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTP---PLS 284 Query: 442 WPQRYNILLG 471 W R I G Sbjct: 285 WHMRCKIAQG 294
>RLK5_ARATH (P47735) Receptor-like protein kinase 5 precursor (EC 2.7.11.1)| Length = 999 Score = 65.5 bits (158), Expect = 7e-11 Identities = 50/164 (30%), Positives = 78/164 (47%), Gaps = 13/164 (7%) Frame = +1 Query: 16 LVALLSLIYTTFIKRPTRCLDGNCLQVARKFSYSELVAA----TDNFSRDRKIGKGSFGD 183 LV ++ ++ R R L + L ++ S+ +L + D IG GS G Sbjct: 637 LVFVVGIVMFIAKCRKLRALKSSTLAASKWRSFHKLHFSEHEIADCLDEKNVIGFGSSGK 696 Query: 184 VYRGLLPMPDLREVAVKEMRQPTL---------KRNRKNYVHEIETLCQLRHKNLLQLIG 336 VY+ L ++ VAVK++ + NR + E+ETL +RHK++++L Sbjct: 697 VYKVELRGGEV--VAVKKLNKSVKGGDDEYSSDSLNRDVFAAEVETLGTIRHKSIVRLWC 754 Query: 337 WCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTLTWPQRYNILL 468 C G +L+YE PNGS++D LH G L WP+R I L Sbjct: 755 CCSSGDCKLLVYEYMPNGSLADVLHGDRKGGVVLGWPERLRIAL 798
>IRAK2_HUMAN (O43187) Interleukin-1 receptor-associated kinase-like 2 (IRAK-2)| Length = 590 Score = 62.8 bits (151), Expect = 4e-10 Identities = 39/123 (31%), Positives = 64/123 (52%) Frame = +1 Query: 106 FSYSELVAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHE 285 +S +++V ATD+F+++RKI +G+F DVYRG ++E + + + E Sbjct: 198 WSEADVVQATDDFNQNRKISQGTFADVYRGHRHGKPFVFKKLRETACSSPGSIERFFQAE 257 Query: 286 IETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTLTWPQRYNIL 465 ++ + H N+L ++G+C IY NGS+ D L G S L WPQR +I Sbjct: 258 LQICLRCCHPNVLPVLGFCAARQFHSFIYPYMANGSLQDRLQGQGGSD-PLPWPQRVSIC 316 Query: 466 LGI 474 G+ Sbjct: 317 SGL 319
>IRAK4_MOUSE (Q8R4K2) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) Length = 459 Score = 61.6 bits (148), Expect = 1e-09 Identities = 38/130 (29%), Positives = 66/130 (50%), Gaps = 8/130 (6%) Frame = +1 Query: 106 FSYSELVAATDNFSRD------RKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNR 267 FS+ EL + T+NF ++G+G FG VY+G + + + M + + + + Sbjct: 168 FSFHELKSITNNFDEQPASAGGNRMGEGGFGVVYKGCVNNTIVAVKKLGAMVEISTEELK 227 Query: 268 KNYVHEIETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLH--DGGASGRTLT 441 + + EI+ + +H+NL++L+G+ D L L+Y PNGS+ D L DG L+ Sbjct: 228 QQFDQEIKVMATCQHENLVELLGFSSDSDNLCLVYAYMPNGSLLDRLSCLDGTP---PLS 284 Query: 442 WPQRYNILLG 471 W R + G Sbjct: 285 WHTRCKVAQG 294
>RPK1_IPONI (P93194) Receptor-like protein kinase precursor (EC 2.7.11.1)| Length = 1109 Score = 61.2 bits (147), Expect = 1e-09 Identities = 39/119 (32%), Positives = 68/119 (57%) Frame = +1 Query: 115 SELVAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIET 294 ++++ AT+N + IGKG+ G +Y+ L PD + AVK++ +K + V EIET Sbjct: 807 NKVLEATENLNDKYVIGKGAHGTIYKATLS-PD-KVYAVKKLVFTGIKNGSVSMVREIET 864 Query: 295 LCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTLTWPQRYNILLG 471 + ++RH+NL++L + +++Y NGS+ D LH+ + L W R+NI +G Sbjct: 865 IGKVRHRNLIKLEEFWLRKEYGLILYTYMENGSLHDILHETNPP-KPLDWSTRHNIAVG 922
>IRAK3_MOUSE (Q8K4B2) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 609 Score = 60.5 bits (145), Expect = 2e-09 Identities = 36/123 (29%), Positives = 66/123 (53%), Gaps = 1/123 (0%) Frame = +1 Query: 109 SYSELVAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEI 288 S+ ++ T +F +D IG+G +VYR + K+ ++ LK++ K ++ E+ Sbjct: 167 SFQSILEGTKHFHKDFLIGEGEIFEVYRVDIRNQAYAVKLFKQEKKMQLKKHWKRFLSEL 226 Query: 289 ETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRT-LTWPQRYNIL 465 E L RH ++L+L + + +L L+Y NG++ D L +G T L+W R ++L Sbjct: 227 EVLLLFRHPHILELAAYFTETEKLCLVYPYMSNGTLFDRLQ--CTNGTTPLSWHVRISVL 284 Query: 466 LGI 474 +GI Sbjct: 285 IGI 287
>NTRK3_SAIBB (Q5IS82) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) Length = 825 Score = 59.7 bits (143), Expect = 4e-09 Identities = 33/99 (33%), Positives = 55/99 (55%), Gaps = 4/99 (4%) Frame = +1 Query: 154 RKIGKGSFGDVYRG----LLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNL 321 R++G+G+FG V+ L P D VAVK ++ PTL RK++ E E L L+H+++ Sbjct: 542 RELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAA-RKDFQREAELLTNLQHEHI 600 Query: 322 LQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTL 438 ++ G C DG L++++E +G ++ L G L Sbjct: 601 VKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMIL 639
>NTRK3_PANTR (Q5IS37) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) Length = 825 Score = 59.7 bits (143), Expect = 4e-09 Identities = 33/99 (33%), Positives = 55/99 (55%), Gaps = 4/99 (4%) Frame = +1 Query: 154 RKIGKGSFGDVYRG----LLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNL 321 R++G+G+FG V+ L P D VAVK ++ PTL RK++ E E L L+H+++ Sbjct: 542 RELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAA-RKDFQREAELLTNLQHEHI 600 Query: 322 LQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTL 438 ++ G C DG L++++E +G ++ L G L Sbjct: 601 VKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMIL 639
>NTRK3_MACFA (Q5IFJ9) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) Length = 825 Score = 59.7 bits (143), Expect = 4e-09 Identities = 33/99 (33%), Positives = 55/99 (55%), Gaps = 4/99 (4%) Frame = +1 Query: 154 RKIGKGSFGDVYRG----LLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNL 321 R++G+G+FG V+ L P D VAVK ++ PTL RK++ E E L L+H+++ Sbjct: 542 RELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAA-RKDFQREAELLTNLQHEHI 600 Query: 322 LQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTL 438 ++ G C DG L++++E +G ++ L G L Sbjct: 601 VKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMIL 639
>NTRK3_RAT (Q03351) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C) Length = 864 Score = 59.7 bits (143), Expect = 4e-09 Identities = 33/99 (33%), Positives = 55/99 (55%), Gaps = 4/99 (4%) Frame = +1 Query: 154 RKIGKGSFGDVYRG----LLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNL 321 R++G+G+FG V+ L P D VAVK ++ PTL RK++ E E L L+H+++ Sbjct: 542 RELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAA-RKDFQREAELLTNLQHEHI 600 Query: 322 LQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTL 438 ++ G C DG L++++E +G ++ L G L Sbjct: 601 VKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMIL 639
>NTRK3_HUMAN (Q16288) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C) Length = 839 Score = 59.7 bits (143), Expect = 4e-09 Identities = 33/99 (33%), Positives = 55/99 (55%), Gaps = 4/99 (4%) Frame = +1 Query: 154 RKIGKGSFGDVYRG----LLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNL 321 R++G+G+FG V+ L P D VAVK ++ PTL RK++ E E L L+H+++ Sbjct: 542 RELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAA-RKDFQREAELLTNLQHEHI 600 Query: 322 LQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTL 438 ++ G C DG L++++E +G ++ L G L Sbjct: 601 VKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMIL 639
>IRAK3_HUMAN (Q9Y616) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 596 Score = 59.7 bits (143), Expect = 4e-09 Identities = 36/122 (29%), Positives = 60/122 (49%) Frame = +1 Query: 109 SYSELVAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEI 288 S+ ++ T NF +D IG+G +VYR + K+ ++ K++ K ++ E+ Sbjct: 154 SFQNIIEGTRNFHKDFLIGEGEIFEVYRVEIQNLTYAVKLFKQEKKMQCKKHWKRFLSEL 213 Query: 289 ETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTLTWPQRYNILL 468 E L H N+L+L + + + LIY NG++ D L G + L W R IL+ Sbjct: 214 EVLLLFHHPNILELAAYFTETEKFCLIYPYMRNGTLFDRLQCVGDTA-PLPWHIRIGILI 272 Query: 469 GI 474 GI Sbjct: 273 GI 274
>NTRK3_CHICK (Q91044) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (Trk-C) Length = 827 Score = 59.3 bits (142), Expect = 5e-09 Identities = 33/99 (33%), Positives = 55/99 (55%), Gaps = 4/99 (4%) Frame = +1 Query: 154 RKIGKGSFGDVYRG----LLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNL 321 R++G+G+FG V+ L P D VAVK ++ PTL RK++ E E L L+H+++ Sbjct: 544 RELGEGAFGKVFLAECYNLSPTNDKMLVAVKALKDPTLAA-RKDFQREAELLTNLQHEHI 602 Query: 322 LQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTL 438 ++ G C DG L++++E +G ++ L G L Sbjct: 603 VKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMIL 641
>TIE2_HUMAN (Q02763) Angiopoietin-1 receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen) Length = 1124 Score = 58.9 bits (141), Expect = 6e-09 Identities = 30/85 (35%), Positives = 51/85 (60%), Gaps = 2/85 (2%) Frame = +1 Query: 160 IGKGSFGDVYRGLLPMPDLR-EVAVKEMRQPTLKRNRKNYVHEIETLCQL-RHKNLLQLI 333 IG+G+FG V + + LR + A+K M++ K + +++ E+E LC+L H N++ L+ Sbjct: 830 IGEGNFGQVLKARIKKDGLRMDAAIKRMKEYASKDDHRDFAGELEVLCKLGHHPNIINLL 889 Query: 334 GWCDDGGRLVLIYELEPNGSVSDHL 408 G C+ G L L E P+G++ D L Sbjct: 890 GACEHRGYLYLAIEYAPHGNLLDFL 914
>TIE2_BOVIN (Q06807) Angiopoietin-1 receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TIE-2) (CD202b antigen) Length = 1125 Score = 58.9 bits (141), Expect = 6e-09 Identities = 30/85 (35%), Positives = 51/85 (60%), Gaps = 2/85 (2%) Frame = +1 Query: 160 IGKGSFGDVYRGLLPMPDLR-EVAVKEMRQPTLKRNRKNYVHEIETLCQL-RHKNLLQLI 333 IG+G+FG V + + LR + A+K M++ K + +++ E+E LC+L H N++ L+ Sbjct: 831 IGEGNFGQVLKARIKKDGLRMDAAIKRMKEYASKDDHRDFAGELEVLCKLGHHPNIINLL 890 Query: 334 GWCDDGGRLVLIYELEPNGSVSDHL 408 G C+ G L L E P+G++ D L Sbjct: 891 GACEHRGYLYLAIEYAPHGNLLDFL 915
>TIE2_MOUSE (Q02858) Angiopoietin-1 receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen) Length = 1122 Score = 58.9 bits (141), Expect = 6e-09 Identities = 30/85 (35%), Positives = 51/85 (60%), Gaps = 2/85 (2%) Frame = +1 Query: 160 IGKGSFGDVYRGLLPMPDLR-EVAVKEMRQPTLKRNRKNYVHEIETLCQL-RHKNLLQLI 333 IG+G+FG V + + LR + A+K M++ K + +++ E+E LC+L H N++ L+ Sbjct: 828 IGEGNFGQVLKARIKKDGLRMDAAIKRMKEYASKDDHRDFAGELEVLCKLGHHPNIINLL 887 Query: 334 GWCDDGGRLVLIYELEPNGSVSDHL 408 G C+ G L L E P+G++ D L Sbjct: 888 GACEHRGYLYLAIEYAPHGNLLDFL 912
>TIE2_BRARE (O73791) Tyrosine-protein kinase receptor Tie-2 precursor (EC| 2.7.10.1) Length = 1116 Score = 57.8 bits (138), Expect = 1e-08 Identities = 30/85 (35%), Positives = 51/85 (60%), Gaps = 2/85 (2%) Frame = +1 Query: 160 IGKGSFGDVYRGLLPMPDLR-EVAVKEMRQPTLKRNRKNYVHEIETLCQLR-HKNLLQLI 333 +G+G+FG V + + LR + AVK M+ + + +++ E+E LC+L HKN++ L+ Sbjct: 822 LGEGNFGQVLKARIRKDGLRMDAAVKRMKDYASQDDHRDFAGELEVLCRLGPHKNIIHLL 881 Query: 334 GWCDDGGRLVLIYELEPNGSVSDHL 408 G C+ G L L E P+G++ D L Sbjct: 882 GACEHRGYLYLAIEFAPHGNLLDFL 906
>NTRK3_PIG (P24786) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C) Length = 825 Score = 56.2 bits (134), Expect = 4e-08 Identities = 32/99 (32%), Positives = 54/99 (54%), Gaps = 4/99 (4%) Frame = +1 Query: 154 RKIGKGSFGDVYRG----LLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNL 321 R++G+G+FG V+ L P VAVK ++ PTL RK++ E E L L+H+++ Sbjct: 542 RELGEGAFGKVFLAECYNLSPTKVKMLVAVKALKDPTLAA-RKDFQREAELLTNLQHEHI 600 Query: 322 LQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTL 438 ++ G C DG L++++E +G ++ L G L Sbjct: 601 VKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMIL 639
>TIE1_BOVIN (Q06805) Tyrosine-protein kinase receptor Tie-1 precursor (EC| 2.7.10.1) Length = 1136 Score = 55.8 bits (133), Expect = 5e-08 Identities = 27/85 (31%), Positives = 51/85 (60%), Gaps = 2/85 (2%) Frame = +1 Query: 160 IGKGSFGDVYRGLLPMPDLR-EVAVKEMRQPTLKRNRKNYVHEIETLCQL-RHKNLLQLI 333 IG+G+FG V R ++ L+ A+K +++ + + +++ E+E LC+L H N++ L+ Sbjct: 843 IGEGNFGQVIRAMIKKDGLKMNAAIKMLKEYASENDHRDFAGELEVLCKLGHHPNIINLL 902 Query: 334 GWCDDGGRLVLIYELEPNGSVSDHL 408 G C++ G L + E P G++ D L Sbjct: 903 GACENRGYLYIAIEYAPYGNLLDFL 927
>TIE1_MOUSE (Q06806) Tyrosine-protein kinase receptor Tie-1 precursor (EC| 2.7.10.1) Length = 1134 Score = 55.8 bits (133), Expect = 5e-08 Identities = 27/85 (31%), Positives = 51/85 (60%), Gaps = 2/85 (2%) Frame = +1 Query: 160 IGKGSFGDVYRGLLPMPDLR-EVAVKEMRQPTLKRNRKNYVHEIETLCQL-RHKNLLQLI 333 IG+G+FG V R ++ L+ A+K +++ + + +++ E+E LC+L H N++ L+ Sbjct: 841 IGEGNFGQVIRAMIKKDGLKMNAAIKMLKEYASENDHRDFAGELEVLCKLGHHPNIINLL 900 Query: 334 GWCDDGGRLVLIYELEPNGSVSDHL 408 G C++ G L + E P G++ D L Sbjct: 901 GACENRGYLYIAIEYAPYGNLLDFL 925
>TESK1_RAT (Q63572) Dual specificity testis-specific protein kinase 1 (EC| 2.7.12.1) (Testicular protein kinase 1) Length = 628 Score = 55.1 bits (131), Expect = 9e-08 Identities = 35/117 (29%), Positives = 59/117 (50%) Frame = +1 Query: 124 VAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQ 303 +A D+F KIG G F +VY+ + + V ++ L NR N + E++ + + Sbjct: 46 LARVDDFDCAEKIGAGFFSEVYK----VRHRQSGQVMVLKMNKLPSNRSNTLREVQLMNR 101 Query: 304 LRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTLTWPQRYNILLGI 474 LRH N+L+ +G C G+L + E G++ L +S L+WP R ++ L I Sbjct: 102 LRHPNILRFMGVCVHQGQLHALTEYMNGGTLEQLL----SSPEPLSWPVRLHLALDI 154
>TESK1_MOUSE (O70146) Dual specificity testis-specific protein kinase 1 (EC| 2.7.12.1) (Testicular protein kinase 1) Length = 627 Score = 55.1 bits (131), Expect = 9e-08 Identities = 35/117 (29%), Positives = 59/117 (50%) Frame = +1 Query: 124 VAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQ 303 +A D+F KIG G F +VY+ + + V ++ L NR N + E++ + + Sbjct: 46 LARVDDFDCAEKIGAGFFSEVYK----VRHRQSGQVMVLKMNKLPSNRSNTLREVQLMNR 101 Query: 304 LRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTLTWPQRYNILLGI 474 LRH N+L+ +G C G+L + E G++ L +S L+WP R ++ L I Sbjct: 102 LRHPNILRFMGVCVHQGQLHALTEYMNGGTLEQLL----SSPEPLSWPVRLHLALDI 154
>TIE1_HUMAN (P35590) Tyrosine-protein kinase receptor Tie-1 precursor (EC| 2.7.10.1) Length = 1138 Score = 54.7 bits (130), Expect = 1e-07 Identities = 27/85 (31%), Positives = 50/85 (58%), Gaps = 2/85 (2%) Frame = +1 Query: 160 IGKGSFGDVYRGLLPMPDLR-EVAVKEMRQPTLKRNRKNYVHEIETLCQL-RHKNLLQLI 333 IG+G+FG V R ++ L+ A+K +++ + + +++ E+E LC+L H N++ L+ Sbjct: 845 IGEGNFGQVIRAMIKKDGLKMNAAIKMLKEYASENDHRDFAGELEVLCKLGHHPNIINLL 904 Query: 334 GWCDDGGRLVLIYELEPNGSVSDHL 408 G C + G L + E P G++ D L Sbjct: 905 GACKNRGYLYIAIEYAPYGNLLDFL 929
>SRK3_SPOLA (P42689) Tyrosine-protein kinase SRK3 (EC 2.7.10.2) (Fragment)| Length = 334 Score = 54.3 bits (129), Expect = 2e-07 Identities = 32/95 (33%), Positives = 54/95 (56%) Frame = +1 Query: 154 RKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLI 333 RK+G+G+FG+V+ G+ VAVK ++ T++ K++V E + + ++ H NLLQL Sbjct: 70 RKLGQGNFGEVWAGV--WNGTTAVAVKTLKPDTMEV--KDFVQEAQVMKKIHHPNLLQLY 125 Query: 334 GWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTL 438 C G + ++ EL GS+ ++L G TL Sbjct: 126 AVCTIGEPIYIVTELMKYGSMLEYLKHGEGKNITL 160
>TESK1_HUMAN (Q15569) Dual specificity testis-specific protein kinase 1 (EC| 2.7.12.1) (Testicular protein kinase 1) Length = 626 Score = 53.9 bits (128), Expect = 2e-07 Identities = 35/117 (29%), Positives = 59/117 (50%) Frame = +1 Query: 124 VAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQ 303 +A D+F KIG G F +VY+ + + V ++ L NR N + E++ + + Sbjct: 51 LARVDDFHCAEKIGAGFFSEVYK----VRHRQSGQVMVLKMNKLPSNRGNTLREVQLMNR 106 Query: 304 LRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTLTWPQRYNILLGI 474 LRH N+L+ +G C G+L + E G++ L +S L+WP R ++ L I Sbjct: 107 LRHPNILRFMGVCVHQGQLHALTEYMNGGTLEQLL----SSPEPLSWPVRLHLALDI 159
>SRC42_DROME (Q9V9J3) Tyrosine-protein kinase Src42A (EC 2.7.10.2) (Dsrc41)| Length = 517 Score = 53.9 bits (128), Expect = 2e-07 Identities = 32/95 (33%), Positives = 54/95 (56%) Frame = +1 Query: 154 RKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLI 333 RK+G G FGDV+ GL + VA+K ++ T+ + K+++ E + + +LRH L+QL Sbjct: 252 RKLGSGQFGDVWEGL--WNNTTPVAIKTLKSGTM--DPKDFLAEAQIMKKLRHTKLIQLY 307 Query: 334 GWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTL 438 C + +I EL +GS+ ++L GR+L Sbjct: 308 AVCTVEEPIYIITELMKHGSLLEYLQAIAGKGRSL 342
>SRK2_SPOLA (P42688) Tyrosine-protein kinase SRK2 (EC 2.7.10.2) (Fragment)| Length = 362 Score = 53.1 bits (126), Expect = 3e-07 Identities = 36/119 (30%), Positives = 65/119 (54%) Frame = +1 Query: 52 IKRPTRCLDGNCLQVARKFSYSELVAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAV 231 +++P R L+ + ++ K + + D+ + RK+G G FG+VY+GL + VAV Sbjct: 66 LRQPCRPLERPQIDLSHK-TKDMWEISRDSITLIRKLGAGQFGEVYQGL--WNNSTPVAV 122 Query: 232 KEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHL 408 K ++ T++ ++ E + + +LRH L+QL C G + +I EL GS+ D+L Sbjct: 123 KTLKAGTMQPAA--FLAEAQIMKKLRHPKLIQLYAVCTQGEPVYIITELMSKGSLLDYL 179
>NTRK1_HUMAN (P04629) High affinity nerve growth factor receptor precursor (EC| 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1 transforming tyrosine kinase protein) (p140-TrkA) (Trk-A) Length = 796 Score = 52.4 bits (124), Expect = 6e-07 Identities = 28/98 (28%), Positives = 56/98 (57%), Gaps = 4/98 (4%) Frame = +1 Query: 157 KIGKGSFGDVY----RGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLL 324 ++G+G+FG V+ LLP D VAVK +++ + + R+++ E E L L+H++++ Sbjct: 515 ELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEAS-ESARQDFQREAELLTMLQHQHIV 573 Query: 325 QLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTL 438 + G C +G L++++E +G ++ L G + L Sbjct: 574 RFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLL 611
>EPB1B_XENLA (Q91736) Ephrin type-B receptor 1-B (EC 2.7.10.1) (Tyrosine-protein| kinase receptor XELK) (Fragment) Length = 902 Score = 52.4 bits (124), Expect = 6e-07 Identities = 27/85 (31%), Positives = 48/85 (56%), Gaps = 2/85 (2%) Frame = +1 Query: 160 IGKGSFGDVYRGLLPMPDLRE--VAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLI 333 IG G FG+VY+G L +P RE VA+K ++ ++ R++++ E + Q H N+++L Sbjct: 543 IGAGEFGEVYKGRLKLPSKREISVAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLE 602 Query: 334 GWCDDGGRLVLIYELEPNGSVSDHL 408 G +++I E NG++ L Sbjct: 603 GVVTKSRPVMIITEFMENGALDSFL 627
>EPB1A_XENLA (Q91571) Ephrin type-B receptor 1-A precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor XEK) Length = 985 Score = 52.4 bits (124), Expect = 6e-07 Identities = 27/85 (31%), Positives = 48/85 (56%), Gaps = 2/85 (2%) Frame = +1 Query: 160 IGKGSFGDVYRGLLPMPDLRE--VAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLI 333 IG G FG+VY+G L +P RE VA+K ++ ++ R++++ E + Q H N+++L Sbjct: 626 IGAGEFGEVYKGRLKLPSKREISVAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLE 685 Query: 334 GWCDDGGRLVLIYELEPNGSVSDHL 408 G +++I E NG++ L Sbjct: 686 GVVTKSRPVMIITEFMENGALDSFL 710
>TMKL1_ARATH (P33543) Putative kinase-like protein TMKL1 precursor| Length = 674 Score = 52.4 bits (124), Expect = 6e-07 Identities = 36/104 (34%), Positives = 57/104 (54%), Gaps = 1/104 (0%) Frame = +1 Query: 166 KGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLIGWCD 345 K S+G VY+ L D +A++ +R+ T K +R + + I L ++RH+NL+ L + Sbjct: 381 KTSYGTVYKAKLS--DGGNIALRLLREGTCK-DRSSCLPVIRQLGRIRHENLVPLRAFYQ 437 Query: 346 DG-GRLVLIYELEPNGSVSDHLHDGGASGRTLTWPQRYNILLGI 474 G +LIY+ PN S+ D LH+ L W +R+ I LGI Sbjct: 438 GKRGEKLLIYDYLPNISLHDLLHESKPRKPALNWARRHKIALGI 481
>TESK2_RAT (Q924U5) Dual specificity testis-specific protein kinase 2 (EC| 2.7.12.1) (Testicular protein kinase 2) Length = 570 Score = 52.4 bits (124), Expect = 6e-07 Identities = 43/145 (29%), Positives = 72/145 (49%), Gaps = 12/145 (8%) Frame = +1 Query: 76 DGNCLQVAR--KFSYSELVAA------TDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAV 231 DGN +QV R SY +++A D+F+R+ KIG G F +V++ + V Sbjct: 29 DGNTVQVGRVSSSSYRAIISAFSRLTSLDDFTRE-KIGSGFFSEVFK----VRHRASGQV 83 Query: 232 KEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLH 411 ++ TL NR N + E++ + +L H N+L+ +G C G+L + E +G++ L Sbjct: 84 MALKMNTLSSNRANLLKEMQLMNRLSHPNILRFMGVCVHQGQLHALTEYINSGNLEQLLD 143 Query: 412 DGGASGRTLTWPQR----YNILLGI 474 S L W R Y+I +G+ Sbjct: 144 ----SNLYLPWTVRVKLAYDIAVGL 164
>CSK_RAT (P32577) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| Length = 450 Score = 52.4 bits (124), Expect = 6e-07 Identities = 44/142 (30%), Positives = 65/142 (45%), Gaps = 17/142 (11%) Frame = +1 Query: 52 IKRPTRCLDGNCLQVARKFSYSELVAATDNFSRD------------RKIGKGSFGDV--- 186 ++ T DG C ++ + VAA D F R + IGKG FGDV Sbjct: 153 VEHYTTDADGLCTRLIKPKVMEGTVAAQDEFYRSGWALNMKELKLLQTIGKGEFGDVMLG 212 Query: 187 -YRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLIG-WCDDGGRL 360 YRG +VAVK ++ + ++ E + QLRH NL+QL+G ++ G L Sbjct: 213 DYRG-------NKVAVKCIKNDA---TAQAFLAEASVMTQLRHSNLVQLLGVIVEEKGGL 262 Query: 361 VLIYELEPNGSVSDHLHDGGAS 426 ++ E GS+ D+L G S Sbjct: 263 YIVTEYMAKGSLVDYLRSRGRS 284
>CSK_MOUSE (P41241) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| (Protein-tyrosine kinase MPK-2) (p50CSK) Length = 450 Score = 52.4 bits (124), Expect = 6e-07 Identities = 44/142 (30%), Positives = 65/142 (45%), Gaps = 17/142 (11%) Frame = +1 Query: 52 IKRPTRCLDGNCLQVARKFSYSELVAATDNFSRD------------RKIGKGSFGDV--- 186 ++ T DG C ++ + VAA D F R + IGKG FGDV Sbjct: 153 VEHYTTDADGLCTRLIKPKVMEGTVAAQDEFYRSGWALNMKELKLLQTIGKGEFGDVMLG 212 Query: 187 -YRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLIG-WCDDGGRL 360 YRG +VAVK ++ + ++ E + QLRH NL+QL+G ++ G L Sbjct: 213 DYRG-------NKVAVKCIKNDA---TAQAFLAEASVMTQLRHSNLVQLLGVIVEEKGGL 262 Query: 361 VLIYELEPNGSVSDHLHDGGAS 426 ++ E GS+ D+L G S Sbjct: 263 YIVTEYMAKGSLVDYLRSRGRS 284
>CSK_HUMAN (P41240) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| (Protein-tyrosine kinase CYL) Length = 450 Score = 52.4 bits (124), Expect = 6e-07 Identities = 44/142 (30%), Positives = 65/142 (45%), Gaps = 17/142 (11%) Frame = +1 Query: 52 IKRPTRCLDGNCLQVARKFSYSELVAATDNFSRD------------RKIGKGSFGDV--- 186 ++ T DG C ++ + VAA D F R + IGKG FGDV Sbjct: 153 VEHYTSDADGLCTRLIKPKVMEGTVAAQDEFYRSGWALNMKELKLLQTIGKGEFGDVMLG 212 Query: 187 -YRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLIG-WCDDGGRL 360 YRG +VAVK ++ + ++ E + QLRH NL+QL+G ++ G L Sbjct: 213 DYRG-------NKVAVKCIKNDA---TAQAFLAEASVMTQLRHSNLVQLLGVIVEEKGGL 262 Query: 361 VLIYELEPNGSVSDHLHDGGAS 426 ++ E GS+ D+L G S Sbjct: 263 YIVTEYMAKGSLVDYLRSRGRS 284
>EPHA3_CHICK (P29318) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (CEK4) Length = 983 Score = 52.0 bits (123), Expect = 8e-07 Identities = 29/96 (30%), Positives = 52/96 (54%), Gaps = 4/96 (4%) Frame = +1 Query: 139 NFSRDRKIGKGSFGDVYRGLLPMPDLRE--VAVKEMRQPTLKRNRKNYVHEIETLCQLRH 312 N S D+ +G G FG+V G L +P +E VA+K ++ ++ R++++ E + Q H Sbjct: 620 NISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKAGYTEKQRRDFLGEASIMGQFDH 679 Query: 313 KNLLQLIGWCDDGGRLVLIYELEPNGSVSDHL--HD 414 N+++L G ++++ E NGS+ L HD Sbjct: 680 PNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHD 715
>TESK2_MOUSE (Q8VCT9) Dual specificity testis-specific protein kinase 2 (EC| 2.7.12.1) (Testicular protein kinase 2) Length = 570 Score = 52.0 bits (123), Expect = 8e-07 Identities = 43/145 (29%), Positives = 72/145 (49%), Gaps = 12/145 (8%) Frame = +1 Query: 76 DGNCLQVAR--KFSYSELVAA------TDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAV 231 DGN +QV R SY +++A D+F+R+ KIG G F +V++ + V Sbjct: 29 DGNTVQVGRVSSSSYRAIISAFSRLTSLDDFTRE-KIGSGFFSEVFK----VRHRASGQV 83 Query: 232 KEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLH 411 ++ TL NR N + E++ + +L H N+L+ +G C G+L + E +G++ L Sbjct: 84 MALKMNTLSSNRANLLKEMQLMNRLSHPNILRFMGVCVHQGQLHALTEYINSGNLEQLLD 143 Query: 412 DGGASGRTLTWPQR----YNILLGI 474 S L W R Y+I +G+ Sbjct: 144 ----SDLYLPWTVRVKLAYDIAVGL 164
>EPHB1_RAT (P09759) Ephrin type-B receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-2) (ELK) Length = 984 Score = 52.0 bits (123), Expect = 8e-07 Identities = 27/85 (31%), Positives = 48/85 (56%), Gaps = 2/85 (2%) Frame = +1 Query: 160 IGKGSFGDVYRGLLPMPDLRE--VAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLI 333 IG G FG+VY+G L +P RE VA+K ++ ++ R++++ E + Q H N+++L Sbjct: 625 IGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLE 684 Query: 334 GWCDDGGRLVLIYELEPNGSVSDHL 408 G +++I E NG++ L Sbjct: 685 GVVTKSRPVMIITEFMENGALDSFL 709
>EPHB1_HUMAN (P54762) Ephrin type-B receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK) Length = 984 Score = 52.0 bits (123), Expect = 8e-07 Identities = 27/85 (31%), Positives = 48/85 (56%), Gaps = 2/85 (2%) Frame = +1 Query: 160 IGKGSFGDVYRGLLPMPDLRE--VAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLI 333 IG G FG+VY+G L +P RE VA+K ++ ++ R++++ E + Q H N+++L Sbjct: 625 IGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLE 684 Query: 334 GWCDDGGRLVLIYELEPNGSVSDHL 408 G +++I E NG++ L Sbjct: 685 GVVTKSRPVMIITEFMENGALDSFL 709
>EPHB1_CHICK (Q07494) Ephrin type-B receptor 1 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor EPH-2) (Tyrosine kinase CEK6 receptor) (Fragment) Length = 984 Score = 52.0 bits (123), Expect = 8e-07 Identities = 27/85 (31%), Positives = 48/85 (56%), Gaps = 2/85 (2%) Frame = +1 Query: 160 IGKGSFGDVYRGLLPMPDLRE--VAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLI 333 IG G FG+VY+G L +P RE VA+K ++ ++ R++++ E + Q H N+++L Sbjct: 625 IGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLE 684 Query: 334 GWCDDGGRLVLIYELEPNGSVSDHL 408 G +++I E NG++ L Sbjct: 685 GVVTKSRPVMIITEFMENGALDSFL 709
>NTRK1_RAT (P35739) High affinity nerve growth factor receptor precursor (EC| 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (p140-TrkA) (Slow nerve growth factor receptor) (Trk-A) Length = 799 Score = 52.0 bits (123), Expect = 8e-07 Identities = 29/98 (29%), Positives = 56/98 (57%), Gaps = 4/98 (4%) Frame = +1 Query: 157 KIGKGSFGDVYRG----LLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLL 324 ++G+G+FG V+ LL D VAVK +++ T + R+++ E E L L+H++++ Sbjct: 518 ELGEGAFGKVFLAECYNLLNDQDKMLVAVKALKE-TSENARQDFHREAELLTMLQHQHIV 576 Query: 325 QLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTL 438 + G C +GG L++++E +G ++ L G + L Sbjct: 577 RFFGVCTEGGPLLMVFEYMRHGDLNRFLRSHGPDAKLL 614
>STK_HYDAT (P17713) Tyrosine-protein kinase STK (EC 2.7.10.2) (P57-STK)| Length = 509 Score = 51.6 bits (122), Expect = 1e-06 Identities = 29/89 (32%), Positives = 52/89 (58%) Frame = +1 Query: 151 DRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQL 330 +RK+G G FG+V+ G+ + +VAVK ++ T+ + +++ E + +LRHK+L+QL Sbjct: 243 NRKLGAGQFGEVWAGV--WNNTTQVAVKTLKPGTM--SPASFLDEAGVMKKLRHKHLVQL 298 Query: 331 IGWCDDGGRLVLIYELEPNGSVSDHLHDG 417 C D + ++ E GS+ D+L G Sbjct: 299 YAICSDREPIYIVTEYMSGGSLLDYLSKG 327
>FLK_RAT (P09760) Tyrosine-protein kinase FLK (EC 2.7.10.2) (Fragment)| Length = 323 Score = 51.6 bits (122), Expect = 1e-06 Identities = 29/85 (34%), Positives = 47/85 (55%) Frame = +1 Query: 136 DNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHK 315 ++ S +GKG+FG+VY+G L D VAVK ++ + + ++ E + L Q H Sbjct: 62 EDVSLGELLGKGNFGEVYKGTLK--DKTPVAVKTCKEDLPQELKIKFLQEAKILKQYDHP 119 Query: 316 NLLQLIGWCDDGGRLVLIYELEPNG 390 N+++LIG C + +I EL P G Sbjct: 120 NIVKLIGVCTQRQPVYIIMELVPGG 144
>EPHA3_HUMAN (P29320) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4) Length = 983 Score = 51.6 bits (122), Expect = 1e-06 Identities = 29/96 (30%), Positives = 52/96 (54%), Gaps = 4/96 (4%) Frame = +1 Query: 139 NFSRDRKIGKGSFGDVYRGLLPMPDLRE--VAVKEMRQPTLKRNRKNYVHEIETLCQLRH 312 N S D+ +G G FG+V G L +P +E VA+K ++ ++ R++++ E + Q H Sbjct: 620 NISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDH 679 Query: 313 KNLLQLIGWCDDGGRLVLIYELEPNGSVSDHL--HD 414 N+++L G ++++ E NGS+ L HD Sbjct: 680 PNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHD 715
>FPS_DROME (P18106) Tyrosine-protein kinase Fps85D (EC 2.7.10.2) (dFer)| Length = 1325 Score = 51.6 bits (122), Expect = 1e-06 Identities = 29/84 (34%), Positives = 47/84 (55%) Frame = +1 Query: 157 KIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLIG 336 +IG+G+FGDVY+ L L +VAVK R ++ ++ E L Q H N+++LIG Sbjct: 1068 RIGRGNFGDVYKAKLKSTKL-DVAVKTCRMTLPDEQKRKFLQEGRILKQYDHPNIVKLIG 1126 Query: 337 WCDDGGRLVLIYELEPNGSVSDHL 408 C ++++ EL GS+ +L Sbjct: 1127 ICVQKQPIMIVMELVLGGSLLTYL 1150
>CSK_CHICK (P41239) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| Length = 450 Score = 51.2 bits (121), Expect = 1e-06 Identities = 44/142 (30%), Positives = 65/142 (45%), Gaps = 17/142 (11%) Frame = +1 Query: 52 IKRPTRCLDGNCLQVARKFSYSELVAATDNFSRD------------RKIGKGSFGDV--- 186 ++ T DG C ++ + VAA D FSR + IGKG FGDV Sbjct: 153 VEHYTTDADGLCSRLIKPKVMEGTVAAQDEFSRSGWALNMKDLKLLQIIGKGEFGDVMLG 212 Query: 187 -YRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLIG-WCDDGGRL 360 YRG +VAVK ++ + ++ E + QLRH NL+QL+G ++ L Sbjct: 213 DYRG-------NKVAVKCIKNDA---TAQAFLAEASVMTQLRHSNLVQLLGVIVEEKSGL 262 Query: 361 VLIYELEPNGSVSDHLHDGGAS 426 ++ E GS+ D+L G S Sbjct: 263 YIVTEYMAKGSLVDYLRSRGRS 284
>ATG1_YEAST (P53104) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) (Autophagy protein 3) (Cytoplasm to vacuole targeting protein 10) Length = 897 Score = 50.8 bits (120), Expect = 2e-06 Identities = 27/73 (36%), Positives = 46/73 (63%), Gaps = 2/73 (2%) Frame = +1 Query: 121 LVAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNR--KNYVHEIET 294 L+A+ N++ +++IGKGSF VYRG L + VA+KE+ + LK + +N EI Sbjct: 17 LMASAGNYTAEKEIGKGSFATVYRGHLTSDKSQHVAIKEVSRAKLKNKKLLENLEIEIAI 76 Query: 295 LCQLRHKNLLQLI 333 L +++H +++ LI Sbjct: 77 LKKIKHPHIVGLI 89
>NTRK1_CHICK (Q91009) High affinity nerve growth factor receptor precursor (EC| 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (Trk-A) (Fragment) Length = 778 Score = 50.8 bits (120), Expect = 2e-06 Identities = 28/98 (28%), Positives = 55/98 (56%), Gaps = 4/98 (4%) Frame = +1 Query: 157 KIGKGSFGDVYRG----LLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLL 324 ++G+G+FG V+ LLP + VAVK +++ T + R ++ E E L L+H++++ Sbjct: 498 ELGEGAFGKVFLAECSHLLPEQEKTLVAVKALKEVT-ENARLDFQREAELLTVLQHEHIV 556 Query: 325 QLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTL 438 + G C +G L++++E +G ++ L G + L Sbjct: 557 KFYGVCTEGDPLIMVFEYMKHGDLNRFLRSHGPDAKIL 594
>EPHA3_BRARE (O13146) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ZEK1) (EPH-like kinase 1) Length = 981 Score = 50.8 bits (120), Expect = 2e-06 Identities = 31/97 (31%), Positives = 51/97 (52%), Gaps = 4/97 (4%) Frame = +1 Query: 139 NFSRDRKIGKGSFGDVYRGLLPMPDLRE--VAVKEMRQPTLKRNRKNYVHEIETLCQLRH 312 N +R IG G FG+V G L +P RE VA+K ++ + R++++ E + Q H Sbjct: 625 NIRIERVIGAGEFGEVCSGRLRLPSKREIQVAIKSLKAGYSEHQRRDFLSEASIMGQFDH 684 Query: 313 KNLLQLIGWCDDGGRLVLIYELEPNGSVSDHL--HDG 417 N+++L G ++++ E NGS+ L HDG Sbjct: 685 PNIIRLEGVVTRCKPVMIVTEYMENGSLDTFLKKHDG 721
>EPHA3_RAT (O08680) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor REK4) (TYRO-4) Length = 984 Score = 50.4 bits (119), Expect = 2e-06 Identities = 28/96 (29%), Positives = 52/96 (54%), Gaps = 4/96 (4%) Frame = +1 Query: 139 NFSRDRKIGKGSFGDVYRGLLPMPDLRE--VAVKEMRQPTLKRNRKNYVHEIETLCQLRH 312 N + D+ +G G FG+V G L +P +E VA+K ++ ++ R++++ E + Q H Sbjct: 621 NIAIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDH 680 Query: 313 KNLLQLIGWCDDGGRLVLIYELEPNGSVSDHL--HD 414 N+++L G ++++ E NGS+ L HD Sbjct: 681 PNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHD 716
>EPHA7_RAT (P54759) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) Length = 998 Score = 50.4 bits (119), Expect = 2e-06 Identities = 30/93 (32%), Positives = 51/93 (54%), Gaps = 4/93 (4%) Frame = +1 Query: 151 DRKIGKGSFGDVYRGLLPMPDLREVAV--KEMRQPTLKRNRKNYVHEIETLCQLRHKNLL 324 +R IG G FG+V G L +P R+VAV K ++ ++ R++++ E + Q H N++ Sbjct: 636 ERVIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVV 695 Query: 325 QLIGWCDDGGRLVLIYELEPNGSVSDHL--HDG 417 L G G ++++ E NG++ L HDG Sbjct: 696 HLEGVVTRGKPVMIVIEFMENGALDAFLRKHDG 728
>EPHA7_MOUSE (Q61772) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1) Length = 998 Score = 50.4 bits (119), Expect = 2e-06 Identities = 30/93 (32%), Positives = 51/93 (54%), Gaps = 4/93 (4%) Frame = +1 Query: 151 DRKIGKGSFGDVYRGLLPMPDLREVAV--KEMRQPTLKRNRKNYVHEIETLCQLRHKNLL 324 +R IG G FG+V G L +P R+VAV K ++ ++ R++++ E + Q H N++ Sbjct: 636 ERVIGAGEFGEVCSGRLKLPGQRDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVV 695 Query: 325 QLIGWCDDGGRLVLIYELEPNGSVSDHL--HDG 417 L G G ++++ E NG++ L HDG Sbjct: 696 HLEGVVTRGKPVMIVIEFMENGALDAFLRKHDG 728
>EPHA7_HUMAN (Q15375) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein-tyrosine kinase HEK11) Length = 998 Score = 50.4 bits (119), Expect = 2e-06 Identities = 30/93 (32%), Positives = 51/93 (54%), Gaps = 4/93 (4%) Frame = +1 Query: 151 DRKIGKGSFGDVYRGLLPMPDLREVAV--KEMRQPTLKRNRKNYVHEIETLCQLRHKNLL 324 +R IG G FG+V G L +P R+VAV K ++ ++ R++++ E + Q H N++ Sbjct: 636 ERVIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVV 695 Query: 325 QLIGWCDDGGRLVLIYELEPNGSVSDHL--HDG 417 L G G ++++ E NG++ L HDG Sbjct: 696 HLEGVVTRGKPVMIVIEFMENGALDAFLRKHDG 728
>ITK_HUMAN (Q08881) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT) Length = 620 Score = 50.1 bits (118), Expect = 3e-06 Identities = 31/113 (27%), Positives = 56/113 (49%) Frame = +1 Query: 70 CLDGNCLQVARKFSYSELVAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQP 249 C V Y + V + ++IG G FG V+ G D +VA+K +R+ Sbjct: 339 CFGRQKAPVTAGLRYGKWVIDPSELTFVQEIGSGQFGLVHLGYWLNKD--KVAIKTIREG 396 Query: 250 TLKRNRKNYVHEIETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHL 408 + + ++++ E E + +L H L+QL G C + + L++E +G +SD+L Sbjct: 397 AM--SEEDFIEEAEVMMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYL 447
>EPHA7_CHICK (O42422) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEPHA7) (Tyrosine-protein kinase receptor CEK11) Length = 993 Score = 50.1 bits (118), Expect = 3e-06 Identities = 30/93 (32%), Positives = 51/93 (54%), Gaps = 4/93 (4%) Frame = +1 Query: 151 DRKIGKGSFGDVYRGLLPMPDLREVAV--KEMRQPTLKRNRKNYVHEIETLCQLRHKNLL 324 +R IG G FG+V G L +P R+VAV K ++ ++ R++++ E + Q H N++ Sbjct: 631 ERVIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVV 690 Query: 325 QLIGWCDDGGRLVLIYELEPNGSVSDHL--HDG 417 L G G ++++ E NG++ L HDG Sbjct: 691 HLEGVVTRGKPVMIVIEYMENGALDAFLRKHDG 723
>EPHA3_MOUSE (P29319) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (MEK4) Length = 983 Score = 50.1 bits (118), Expect = 3e-06 Identities = 29/96 (30%), Positives = 51/96 (53%), Gaps = 4/96 (4%) Frame = +1 Query: 139 NFSRDRKIGKGSFGDVYRGLLPMPDLRE--VAVKEMRQPTLKRNRKNYVHEIETLCQLRH 312 N S D+ +G G FG+V G L +P +E VA+K ++ ++ R++++ E + Q H Sbjct: 620 NISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDH 679 Query: 313 KNLLQLIGWCDDGGRLVLIYELEPNGSVSDHL--HD 414 N+++L G +++ E NGS+ L HD Sbjct: 680 PNIIRLEGVVTKSKPEMIVTEYMENGSLDSFLRKHD 715
>NTRK2_RAT (Q63604) BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B) Length = 821 Score = 49.7 bits (117), Expect = 4e-06 Identities = 29/98 (29%), Positives = 53/98 (54%), Gaps = 4/98 (4%) Frame = +1 Query: 139 NFSRDRKIGKGSFGDVYRG----LLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQL 306 N R++G+G+FG V+ L P D VAVK ++ + RK++ E E L L Sbjct: 536 NIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDAS-DNARKDFHREAELLTNL 594 Query: 307 RHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGG 420 +H+++++ G C +G L++++E +G ++ L G Sbjct: 595 QHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHG 632
>NTRK2_MOUSE (P15209) BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B) Length = 821 Score = 49.7 bits (117), Expect = 4e-06 Identities = 29/98 (29%), Positives = 53/98 (54%), Gaps = 4/98 (4%) Frame = +1 Query: 139 NFSRDRKIGKGSFGDVYRG----LLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQL 306 N R++G+G+FG V+ L P D VAVK ++ + RK++ E E L L Sbjct: 536 NIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDAS-DNARKDFHREAELLTNL 594 Query: 307 RHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGG 420 +H+++++ G C +G L++++E +G ++ L G Sbjct: 595 QHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHG 632
>NTRK2_CHICK (Q91987) BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (Trk-B) Length = 818 Score = 49.7 bits (117), Expect = 4e-06 Identities = 29/98 (29%), Positives = 53/98 (54%), Gaps = 4/98 (4%) Frame = +1 Query: 139 NFSRDRKIGKGSFGDVYRG----LLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQL 306 N R++G+G+FG V+ L P D VAVK ++ + RK++ E E L L Sbjct: 533 NIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDAS-DNARKDFHREAELLTNL 591 Query: 307 RHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGG 420 +H+++++ G C +G L++++E +G ++ L G Sbjct: 592 QHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHG 629
>NTRK2_HUMAN (Q16620) BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB) (Trk-B) Length = 822 Score = 49.7 bits (117), Expect = 4e-06 Identities = 29/98 (29%), Positives = 53/98 (54%), Gaps = 4/98 (4%) Frame = +1 Query: 139 NFSRDRKIGKGSFGDVYRG----LLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQL 306 N R++G+G+FG V+ L P D VAVK ++ + RK++ E E L L Sbjct: 537 NIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDAS-DNARKDFHREAELLTNL 595 Query: 307 RHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGG 420 +H+++++ G C +G L++++E +G ++ L G Sbjct: 596 QHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHG 633
>MUSK_CHICK (Q8AXY6) Muscle, skeletal receptor tyrosine protein kinase| precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK) Length = 947 Score = 49.7 bits (117), Expect = 4e-06 Identities = 27/97 (27%), Positives = 52/97 (53%), Gaps = 4/97 (4%) Frame = +1 Query: 136 DNFSRDRKIGKGSFGDVYR----GLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQ 303 +N R IG+G+FG V++ GLLP VAVK +++ + ++ E + + Sbjct: 653 NNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAE 712 Query: 304 LRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHD 414 + N+++L+G C G + L++E G ++++L D Sbjct: 713 FDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEYLRD 749
>SRMS_HUMAN (Q9H3Y6) Tyrosine-protein kinase Srms (EC 2.7.10.2)| Length = 488 Score = 49.7 bits (117), Expect = 4e-06 Identities = 36/106 (33%), Positives = 55/106 (51%), Gaps = 4/106 (3%) Frame = +1 Query: 142 FSRDRKIGKGSFGDVYRGL----LPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLR 309 F+ RK+G+G FG+V+ GL LP VA+K ++ +K + EI+TL LR Sbjct: 230 FALGRKLGEGYFGEVWEGLWLGSLP------VAIKVIKSANMKLT--DLAKEIQTLKGLR 281 Query: 310 HKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTLTWP 447 H+ L++L C G + ++ EL G++ L G GR L P Sbjct: 282 HERLIRLHAVCSGGEPVYIVTELMRKGNLQAFL--GTPEGRALRLP 325
>HTK16_HYDAT (P53356) Tyrosine-protein kinase HTK16 (EC 2.7.10.2)| Length = 757 Score = 49.3 bits (116), Expect = 5e-06 Identities = 28/95 (29%), Positives = 53/95 (55%), Gaps = 2/95 (2%) Frame = +1 Query: 136 DNFSRDRKIGKGSFGDVYRGLLPMPDLRE--VAVKEMRQPTLKRNRKNYVHEIETLCQLR 309 ++ S +++G G FG V +G+ P +E VA+K + + + + K ++ E + QL Sbjct: 482 ESISFGKELGVGEFGSVIKGIWLSPGGKEINVAMKTLHKDKMVQGEKEFLREALVMSQLN 541 Query: 310 HKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHD 414 H ++ L+G C G ++L+ EL G++ D+L D Sbjct: 542 HPCIVSLLGVC-LGPPMILVQELVEMGALLDYLMD 575
>FGFR2_DROME (Q09147) Fibroblast growth factor receptor homolog 2 precursor (EC| 2.7.10.1) (Protein breathless) (dFGF-R1) Length = 1052 Score = 49.3 bits (116), Expect = 5e-06 Identities = 31/90 (34%), Positives = 50/90 (55%), Gaps = 7/90 (7%) Frame = +1 Query: 160 IGKGSFGDVY----RGLLPMPDLRE--VAVKEMRQPTLKRNRKNYVHEIETLCQL-RHKN 318 +G+G+FG V GL P L E VAVK +++ + + V E+E + + +H N Sbjct: 718 LGEGAFGRVVMAEAEGLPRSPQLAETIVAVKMVKEEHTDTDMASLVREMEVMKMIGKHIN 777 Query: 319 LLQLIGWCDDGGRLVLIYELEPNGSVSDHL 408 ++ L+G C GG L +I E P+G++ D L Sbjct: 778 IINLLGCCSQGGPLWVIVEYAPHGNLKDFL 807
>EPHB2_CHICK (P28693) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK5) Length = 1004 Score = 49.3 bits (116), Expect = 5e-06 Identities = 27/88 (30%), Positives = 47/88 (53%), Gaps = 2/88 (2%) Frame = +1 Query: 151 DRKIGKGSFGDVYRGLLPMPDLRE--VAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLL 324 ++ IG G FG+V G L +P RE VA+K ++ ++ R++++ E + Q H N++ Sbjct: 642 EQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVI 701 Query: 325 QLIGWCDDGGRLVLIYELEPNGSVSDHL 408 L G +++I E NGS+ L Sbjct: 702 HLEGVVTKSSPVMIITEFMENGSLDSFL 729
>TESK2_HUMAN (Q96S53) Dual specificity testis-specific protein kinase 2 (EC| 2.7.12.1) (Testicular protein kinase 2) Length = 571 Score = 49.3 bits (116), Expect = 5e-06 Identities = 41/144 (28%), Positives = 68/144 (47%), Gaps = 11/144 (7%) Frame = +1 Query: 76 DGNCLQVARKF--SYSELVAATDNFSR-----DRKIGKGSFGDVYRGLLPMPDLREVAVK 234 +GN QV R + SY L++A +R KIG G F +V++ + V Sbjct: 29 EGNVSQVGRVWPSSYRALISAFSRLTRLDDFTCEKIGSGFFSEVFK----VRHRASGQVM 84 Query: 235 EMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHD 414 ++ TL NR N + E++ + +L H N+L+ +G C G+L + E +G++ L Sbjct: 85 ALKMNTLSSNRANMLKEVQLMNRLSHPNILRFMGVCVHQGQLHALTEYINSGNLEQLLD- 143 Query: 415 GGASGRTLTWPQR----YNILLGI 474 S L W R Y+I +G+ Sbjct: 144 ---SNLHLPWTVRVKLAYDIAVGL 164
>EPHB2_COTJA (Q90344) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor QEK5) Length = 987 Score = 49.3 bits (116), Expect = 5e-06 Identities = 27/88 (30%), Positives = 47/88 (53%), Gaps = 2/88 (2%) Frame = +1 Query: 151 DRKIGKGSFGDVYRGLLPMPDLRE--VAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLL 324 ++ IG G FG+V G L +P RE VA+K ++ ++ R++++ E + Q H N++ Sbjct: 625 EQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVI 684 Query: 325 QLIGWCDDGGRLVLIYELEPNGSVSDHL 408 L G +++I E NGS+ L Sbjct: 685 HLEGVVTKSSPVMIITEFMENGSLDSFL 712
>FES_MOUSE (P16879) Proto-oncogene tyrosine-protein kinase Fes/Fps (EC| 2.7.10.2) (C-Fes) Length = 820 Score = 49.3 bits (116), Expect = 5e-06 Identities = 31/95 (32%), Positives = 46/95 (48%) Frame = +1 Query: 157 KIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLIG 336 +IG+G+FG+V+ G L D VAVK R+ + ++ E L Q H N+++LIG Sbjct: 564 QIGRGNFGEVFSGRL-RADNTPVAVKSCRETLPPDLKAKFLQEARILKQYNHPNIVRLIG 622 Query: 337 WCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTLT 441 C + ++ EL G L GA R T Sbjct: 623 VCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVKT 657
>EPHA1_MOUSE (Q60750) Ephrin type-A receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ESK) Length = 977 Score = 48.9 bits (115), Expect = 7e-06 Identities = 28/90 (31%), Positives = 48/90 (53%), Gaps = 2/90 (2%) Frame = +1 Query: 151 DRKIGKGSFGDVYRGLLPMP--DLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLL 324 D IG+G FG+VYRG L +P D + VA+K ++ + N++ E + Q H ++L Sbjct: 628 DTVIGEGEFGEVYRGALRLPSQDCKTVAIKTLKDTSPDGYWWNFLREATIMGQFNHPHIL 687 Query: 325 QLIGWCDDGGRLVLIYELEPNGSVSDHLHD 414 +L G +++I E NG++ L + Sbjct: 688 RLEGVITKRKPIMIITEFMENGALDAFLKE 717
>EPHA5_MOUSE (Q60629) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7) Length = 877 Score = 48.9 bits (115), Expect = 7e-06 Identities = 27/88 (30%), Positives = 47/88 (53%), Gaps = 2/88 (2%) Frame = +1 Query: 151 DRKIGKGSFGDVYRGLLPMPDLRE--VAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLL 324 +R IG G FG+V G L +P RE VA+K ++ ++ R++++ E + Q H N++ Sbjct: 517 ERVIGAGEFGEVCSGCLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNII 576 Query: 325 QLIGWCDDGGRLVLIYELEPNGSVSDHL 408 L G ++++ E NGS+ L Sbjct: 577 HLEGVVTKSKPVMIVTEYMENGSLDTFL 604
>TXK_MOUSE (P42682) Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18)| (Resting lymphocyte kinase) Length = 527 Score = 48.9 bits (115), Expect = 7e-06 Identities = 31/114 (27%), Positives = 57/114 (50%), Gaps = 2/114 (1%) Frame = +1 Query: 79 GNCLQVARKFSYSELVAATDNFSRDRKIGKGSFGDVYRG--LLPMPDLREVAVKEMRQPT 252 G+CL FSY + + ++IG G FG V+ G +P VA+K + + + Sbjct: 250 GSCLPATSGFSYEKWEIDPSELAFVKEIGSGQFGVVHLGEWRAHIP----VAIKAINEGS 305 Query: 253 LKRNRKNYVHEIETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHD 414 + + ++++ E + + +L H L+QL G C L ++ E NG + D+L + Sbjct: 306 M--SEEDFIEEAKVMMKLSHSRLVQLYGVCIQQKPLYIVTEFMENGCLLDYLRE 357
>TXK_HUMAN (P42681) Tyrosine-protein kinase TXK (EC 2.7.10.2)| Length = 527 Score = 48.9 bits (115), Expect = 7e-06 Identities = 30/114 (26%), Positives = 57/114 (50%) Frame = +1 Query: 73 LDGNCLQVARKFSYSELVAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPT 252 L G+CL FSY + + ++IG G FG V+ G +VA+K + + + Sbjct: 248 LMGSCLPATAGFSYEKWEIDPSELAFIKEIGSGQFGVVHLG--EWRSHIQVAIKAINEGS 305 Query: 253 LKRNRKNYVHEIETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHD 414 + + ++++ E + + +L H L+QL G C L ++ E NG + ++L + Sbjct: 306 M--SEEDFIEEAKVMMKLSHSKLVQLYGVCIQRKPLYIVTEFMENGCLLNYLRE 357
>FRK_HUMAN (P42685) Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear| tyrosine protein kinase RAK) Length = 505 Score = 48.9 bits (115), Expect = 7e-06 Identities = 38/145 (26%), Positives = 69/145 (47%), Gaps = 14/145 (9%) Frame = +1 Query: 49 FIKRPTRCLDGNCLQVARKFSYSELVA-------ATDNFSRDR-------KIGKGSFGDV 186 F+ T+ DG C+++ + ++ A D + DR ++G G FG+V Sbjct: 189 FVSHYTKTSDGLCVKLGKPCLKIQVPAPFDLSYKTVDQWEIDRNSIQLLKRLGSGQFGEV 248 Query: 187 YRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLIGWCDDGGRLVL 366 + GL + VAVK ++ ++ N +++ E + + LRH L+QL C + + Sbjct: 249 WEGL--WNNTTPVAVKTLKPGSMDPN--DFLREAQIMKNLRHPKLIQLYAVCTLEDPIYI 304 Query: 367 IYELEPNGSVSDHLHDGGASGRTLT 441 I EL +GS+ ++L + S LT Sbjct: 305 ITELMRHGSLQEYLQNDTGSKIHLT 329
>EPHA1_HUMAN (P21709) Ephrin type-A receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH) Length = 976 Score = 48.9 bits (115), Expect = 7e-06 Identities = 28/90 (31%), Positives = 47/90 (52%), Gaps = 2/90 (2%) Frame = +1 Query: 151 DRKIGKGSFGDVYRGLLPMP--DLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLL 324 D IG+G FG+VYRG L +P D + VA+K ++ + N++ E + Q H ++L Sbjct: 627 DTVIGEGEFGEVYRGTLRLPSQDCKTVAIKTLKDTSPGGQWWNFLREATIMGQFSHPHIL 686 Query: 325 QLIGWCDDGGRLVLIYELEPNGSVSDHLHD 414 L G +++I E NG++ L + Sbjct: 687 HLEGVVTKRKPIMIITEFMENGALDAFLRE 716
>EPHB4_MOUSE (P54761) Ephrin type-B receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK-1) Length = 987 Score = 48.9 bits (115), Expect = 7e-06 Identities = 28/90 (31%), Positives = 49/90 (54%), Gaps = 4/90 (4%) Frame = +1 Query: 160 IGKGSFGDVYRGLLPMPDLRE--VAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLI 333 IG G FG+V RG L P +E VA+K ++ +R R+ ++ E + Q H N+++L Sbjct: 621 IGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRLE 680 Query: 334 GWCDDGGRLVLIYELEPNGSVSD--HLHDG 417 G + ++++ E NG++ L+DG Sbjct: 681 GVVTNSVPVMILTEFMENGALDSFLRLNDG 710
>EPHB4_HUMAN (P54760) Ephrin type-B receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor HTK) Length = 987 Score = 48.9 bits (115), Expect = 7e-06 Identities = 28/90 (31%), Positives = 49/90 (54%), Gaps = 4/90 (4%) Frame = +1 Query: 160 IGKGSFGDVYRGLLPMPDLRE--VAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLI 333 IG G FG+V RG L P +E VA+K ++ +R R+ ++ E + Q H N+++L Sbjct: 621 IGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRLE 680 Query: 334 GWCDDGGRLVLIYELEPNGSVSD--HLHDG 417 G + ++++ E NG++ L+DG Sbjct: 681 GVVTNSMPVMILTEFMENGALDSFLRLNDG 710
>ROR1_DROME (Q24488) Tyrosine-protein kinase transmembrane receptor Ror| precursor (EC 2.7.10.1) (dRor) Length = 685 Score = 48.9 bits (115), Expect = 7e-06 Identities = 28/109 (25%), Positives = 61/109 (55%), Gaps = 3/109 (2%) Frame = +1 Query: 157 KIGKGSFGDVYRGLLPMPDLRE--VAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQL 330 ++G+G+FG VY+G L P+ VA+K +++ + ++++ EIE + L+H+N++ + Sbjct: 415 ELGEGAFGKVYKGQLLQPNKTTITVAIKALKENASVKTQQDFKREIELISDLKHQNIVCI 474 Query: 331 IGWCDDGGRLVLIYELEPNGSVSDHL-HDGGASGRTLTWPQRYNILLGI 474 +G + +++E NG + + L + G++L+ + I L I Sbjct: 475 LGVVLNKEPYCMLFEYMANGDLHEFLISNSPTEGKSLSQLEFLQIALQI 523
>IGF1R_XENLA (O73798) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (xIGF-1R) (xIGFR) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1358 Score = 48.9 bits (115), Expect = 7e-06 Identities = 37/145 (25%), Positives = 70/145 (48%), Gaps = 13/145 (8%) Frame = +1 Query: 13 LLVALLSLIYTTFIKRPTRCLDGNCLQVA---RKFSYSELVAAT------DNFSRDRKIG 165 LLV ++S++ F KR + L L + FS +E+ + + +R++G Sbjct: 943 LLVGIISIVCFVFKKRNSNRLGNGVLYASVNPEYFSAAEMYVPDKWEVPREKITMNRELG 1002 Query: 166 KGSFGDVYRGLLP--MPDLRE--VAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLI 333 +GSFG VY G+ + D E VA+K + + R R +++E + + ++++L+ Sbjct: 1003 QGSFGMVYEGIAKGVVKDEAETKVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLL 1062 Query: 334 GWCDDGGRLVLIYELEPNGSVSDHL 408 G G ++I EL G + +L Sbjct: 1063 GVVSQGQPTLVIMELMTRGDLKSYL 1087
>EPHB2_MOUSE (P54763) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3) Length = 994 Score = 48.5 bits (114), Expect = 9e-06 Identities = 27/88 (30%), Positives = 47/88 (53%), Gaps = 2/88 (2%) Frame = +1 Query: 151 DRKIGKGSFGDVYRGLLPMPDLRE--VAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLL 324 ++ IG G FG+V G L +P RE VA+K ++ ++ R++++ E + Q H N++ Sbjct: 632 EQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVI 691 Query: 325 QLIGWCDDGGRLVLIYELEPNGSVSDHL 408 L G +++I E NGS+ L Sbjct: 692 HLEGVVTKSTPVMIITEFMENGSLDSFL 719
>EPHA5_HUMAN (P54756) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein-tyrosine kinase HEK7) Length = 1037 Score = 48.5 bits (114), Expect = 9e-06 Identities = 27/88 (30%), Positives = 47/88 (53%), Gaps = 2/88 (2%) Frame = +1 Query: 151 DRKIGKGSFGDVYRGLLPMPDLRE--VAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLL 324 +R IG G FG+V G L +P RE VA+K ++ ++ R++++ E + Q H N++ Sbjct: 678 ERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNII 737 Query: 325 QLIGWCDDGGRLVLIYELEPNGSVSDHL 408 L G ++++ E NGS+ L Sbjct: 738 HLEGVVTKSKPVMIVTEYMENGSLDTFL 765
>FER_HUMAN (P16591) Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2)| (p94-FER) (c-FER) Length = 822 Score = 48.5 bits (114), Expect = 9e-06 Identities = 27/77 (35%), Positives = 43/77 (55%) Frame = +1 Query: 160 IGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLIGW 339 +GKG+FG+VY+G L D VAVK ++ + + ++ E + L Q H N+++LIG Sbjct: 569 LGKGNFGEVYKGTLK--DKTSVAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGV 626 Query: 340 CDDGGRLVLIYELEPNG 390 C + +I EL G Sbjct: 627 CTQRQPVYIIMELVSGG 643
>ITK_MOUSE (Q03526) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK) Length = 625 Score = 48.5 bits (114), Expect = 9e-06 Identities = 28/99 (28%), Positives = 54/99 (54%) Frame = +1 Query: 112 YSELVAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIE 291 Y + V + ++IG G FG V+ G D +VA+K +++ + + ++++ E E Sbjct: 358 YGKWVIQPSELTFVQEIGSGQFGLVHLGYWLNKD--KVAIKTIQEGAM--SEEDFIEEAE 413 Query: 292 TLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHL 408 + +L H L+QL G C + + L++E +G +SD+L Sbjct: 414 VMMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYL 452
>FPS_FUJSV (P00530) Tyrosine-protein kinase transforming protein FPS (EC| 2.7.10.2) Length = 873 Score = 48.5 bits (114), Expect = 9e-06 Identities = 28/88 (31%), Positives = 43/88 (48%) Frame = +1 Query: 157 KIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLIG 336 +IG+G+FG+V+ G L D VAVK R+ + ++ E L Q H N+++LIG Sbjct: 617 RIGRGNFGEVFSGRL-RADNTPVAVKSCRETLPPELKAKFLQEARILKQCNHPNIVRLIG 675 Query: 337 WCDDGGRLVLIYELEPNGSVSDHLHDGG 420 C + ++ EL G L G Sbjct: 676 VCTQKQPIYIVMELVQGGDFLSFLRSKG 703
>EPHA8_HUMAN (P29322) Ephrin type-A receptor 8 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3) Length = 1005 Score = 48.5 bits (114), Expect = 9e-06 Identities = 35/120 (29%), Positives = 59/120 (49%), Gaps = 13/120 (10%) Frame = +1 Query: 97 ARKFSYSELVAATDNFSRD---------RKIGKGSFGDVYRGLLPMPDLREV--AVKEMR 243 A +Y E A +F+R+ + IG G G+V G L +P R+V A+K ++ Sbjct: 611 AEPHTYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIKALK 670 Query: 244 QPTLKRNRKNYVHEIETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHL--HDG 417 +R R++++ E + Q H N+++L G G +++ E NGS+ L HDG Sbjct: 671 AGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRTHDG 730
>EPHB2_HUMAN (P29323) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen) Length = 1055 Score = 48.5 bits (114), Expect = 9e-06 Identities = 27/88 (30%), Positives = 47/88 (53%), Gaps = 2/88 (2%) Frame = +1 Query: 151 DRKIGKGSFGDVYRGLLPMPDLRE--VAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLL 324 ++ IG G FG+V G L +P RE VA+K ++ ++ R++++ E + Q H N++ Sbjct: 624 EQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVI 683 Query: 325 QLIGWCDDGGRLVLIYELEPNGSVSDHL 408 L G +++I E NGS+ L Sbjct: 684 HLEGVVTKSTPVMIITEFMENGSLDSFL 711
>EGL15_CAEEL (Q10656) Myoblast growth factor receptor egl-15 precursor (EC| 2.7.10.1) (Egg-laying defective protein 15) Length = 1040 Score = 48.5 bits (114), Expect = 9e-06 Identities = 28/86 (32%), Positives = 51/86 (59%), Gaps = 3/86 (3%) Frame = +1 Query: 160 IGKGSFGDVYRGLLPMPDLRE--VAVKEMRQPTLKRNRKNYVHEIETLCQL-RHKNLLQL 330 +G+G+FG+V++ + E VAVK+++ ++ + V E+ET + H+N+L+L Sbjct: 646 LGEGAFGEVWKATYKETENNEIAVAVKKLKMSAHEKELIDLVSEMETFKVIGEHENVLRL 705 Query: 331 IGWCDDGGRLVLIYELEPNGSVSDHL 408 IG C G L ++ EL +G++ D L Sbjct: 706 IGCCTGAGPLYVVVELCKHGNLRDFL 731
>FPS_AVISP (P00541) Tyrosine-protein kinase transforming protein Fps (EC| 2.7.10.2) Length = 533 Score = 48.5 bits (114), Expect = 9e-06 Identities = 28/88 (31%), Positives = 43/88 (48%) Frame = +1 Query: 157 KIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLIG 336 +IG+G+FG+V+ G L D VAVK R+ + ++ E L Q H N+++LIG Sbjct: 277 RIGRGNFGEVFSGRL-RADNTPVAVKSCRETLPPELKAKFLQEARILKQYNHPNIVRLIG 335 Query: 337 WCDDGGRLVLIYELEPNGSVSDHLHDGG 420 C + ++ EL G L G Sbjct: 336 VCTQKQPIYIVMELVQGGDFLSFLRSKG 363
>INSR_DROME (P09208) Insulin-like receptor precursor (EC 2.7.10.1) (DIR) (DInr)| (dIRH) [Contains: Insulin-like receptor alpha subunit; Insulin-like receptor beta 1 subunit; Insulin-like receptor beta 2 subunit] Length = 2144 Score = 48.1 bits (113), Expect = 1e-05 Identities = 27/95 (28%), Positives = 49/95 (51%), Gaps = 4/95 (4%) Frame = +1 Query: 136 DNFSRDRKIGKGSFGDVYRGLL----PMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQ 303 +N + +G+GSFG VY G+L P RE A+K + + R R N++ E + + Sbjct: 1369 ENIIQLAPLGQGSFGMVYEGILKSFPPNGVDRECAIKTVNENATDRERTNFLSEASVMKE 1428 Query: 304 LRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHL 408 ++++L+G C G +++ EL G + +L Sbjct: 1429 FDTYHVVRLLGVCSRGQPALVVMELMKKGDLKSYL 1463
>FES_FELCA (P14238) Proto-oncogene tyrosine-protein kinase FES/FPS (EC| 2.7.10.2) (C-FES) Length = 820 Score = 48.1 bits (113), Expect = 1e-05 Identities = 31/95 (32%), Positives = 47/95 (49%) Frame = +1 Query: 157 KIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLIG 336 +IG+G+FG+V+ G L D VAVK R+ + ++ E + L Q H N+++LIG Sbjct: 564 QIGRGNFGEVFSGRL-RADNTLVAVKSCRETLPPDIKAKFLQEAKILKQYSHPNIVRLIG 622 Query: 337 WCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTLT 441 C + ++ EL G L GA R T Sbjct: 623 VCTQKQPIYIVMELVQGGDFLTFLRTEGARLRMKT 657
>FES_FSVGA (P00542) Tyrosine-protein kinase transforming protein Fes (EC| 2.7.10.2) Length = 609 Score = 48.1 bits (113), Expect = 1e-05 Identities = 31/95 (32%), Positives = 47/95 (49%) Frame = +1 Query: 157 KIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLIG 336 +IG+G+FG+V+ G L D VAVK R+ + ++ E + L Q H N+++LIG Sbjct: 353 QIGRGNFGEVFSGRL-RADNTLVAVKSCRETLPPDIKAKFLQEAKILKQYSHPNIVRLIG 411 Query: 337 WCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTLT 441 C + ++ EL G L GA R T Sbjct: 412 VCTQKQPIYIVMELVQGGDFLTFLRTEGARLRMKT 446
>FES_HUMAN (P07332) Proto-oncogene tyrosine-protein kinase Fes/Fps (EC| 2.7.10.2) (C-Fes) Length = 822 Score = 48.1 bits (113), Expect = 1e-05 Identities = 31/95 (32%), Positives = 46/95 (48%) Frame = +1 Query: 157 KIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLIG 336 +IG+G+FG+V+ G L D VAVK R+ + ++ E L Q H N+++LIG Sbjct: 566 QIGRGNFGEVFSGRL-RADNTLVAVKSCRETLPPDLKAKFLQEARILKQYSHPNIVRLIG 624 Query: 337 WCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTLT 441 C + ++ EL G L GA R T Sbjct: 625 VCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVKT 659
>FES_FSVST (P00543) Tyrosine-protein kinase transforming protein Fes (EC| 2.7.10.2) Length = 477 Score = 48.1 bits (113), Expect = 1e-05 Identities = 31/95 (32%), Positives = 47/95 (49%) Frame = +1 Query: 157 KIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLIG 336 +IG+G+FG+V+ G L D VAVK R+ + ++ E + L Q H N+++LIG Sbjct: 221 QIGRGNFGEVFSGRL-RADNTLVAVKSCRETLPPDIKAKFLQEAKILKQYSHPNIVRLIG 279 Query: 337 WCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTLT 441 C + ++ EL G L GA R T Sbjct: 280 VCTQKQPIYIVMELVQGGDFLTFLRTEGARLRMKT 314
>SHARK_DROME (Q24145) Tyrosine-protein kinase shark (EC 2.7.10.2)| Length = 939 Score = 47.8 bits (112), Expect = 1e-05 Identities = 34/108 (31%), Positives = 53/108 (49%), Gaps = 10/108 (9%) Frame = +1 Query: 151 DRKIGKGSFGDVYRGLL------PMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRH 312 DR+IG G FG V+ G L EVA+K + N++ ++ E + +L H Sbjct: 665 DREIGHGEFGSVHSGWLLRKSGAGEESRLEVAIKMLSDE--HSNKQEFLREASVMMRLEH 722 Query: 313 KNLLQLIGWCDDGGRLVLIYELEPNGS----VSDHLHDGGASGRTLTW 444 K +++LIG G L+++ EL P GS + DH H+ A+ W Sbjct: 723 KCIVRLIG-IAKGEMLMMVQELAPLGSMLQYILDHGHEITANAELKVW 769
>EPHA8_RAT (P29321) Ephrin type-A receptor 8 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor EEK) (EPH- and ELK-related kinase) (Fragment) Length = 372 Score = 47.8 bits (112), Expect = 1e-05 Identities = 29/93 (31%), Positives = 50/93 (53%), Gaps = 4/93 (4%) Frame = +1 Query: 151 DRKIGKGSFGDVYRGLLPMPDLREV--AVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLL 324 ++ IG G G+V G L +P R+V A+K ++ +R R++++ E + Q H N++ Sbjct: 5 EKIIGSGESGEVCYGRLQVPGQRDVPVAIKALKAGYTERQRQDFLREAAIMGQFDHPNII 64 Query: 325 QLIGWCDDGGRLVLIYELEPNGSVSDHL--HDG 417 +L G G +++ E NGS+ L HDG Sbjct: 65 RLEGVVTRGRLAMIVTEYMENGSLDAFLRTHDG 97
>AURKB_RAT (O55099) Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-| and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora-B) Length = 343 Score = 47.8 bits (112), Expect = 1e-05 Identities = 38/122 (31%), Positives = 54/122 (44%), Gaps = 2/122 (1%) Frame = +1 Query: 61 PTRCLDGNCLQVARKFSYSELVAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEM 240 P + L N A + S S DNF R +GKG FG+VY VA+K + Sbjct: 53 PGQKLTENKGATALQGSQSRQPFTIDNFEIGRPLGKGKFGNVYLAREKKSRFI-VALKIL 111 Query: 241 RQPTLKRNRKNYV--HEIETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHD 414 + +++ + EIE L+H N+LQL + D R+ LI E P G + L Sbjct: 112 FKSQIEKEGVEHQLRREIEIQAHLKHPNILQLYNYFYDQQRIYLILEYAPRGELYKELQK 171 Query: 415 GG 420 G Sbjct: 172 SG 173
>EPHA5_RAT (P54757) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) Length = 1005 Score = 47.8 bits (112), Expect = 1e-05 Identities = 27/88 (30%), Positives = 46/88 (52%), Gaps = 2/88 (2%) Frame = +1 Query: 151 DRKIGKGSFGDVYRGLLPMPDLRE--VAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLL 324 +R IG G FG+V G L +P RE VA K ++ ++ R++++ E + Q H N++ Sbjct: 680 ERVIGAGEFGEVCSGRLKLPGKRELPVATKTLKVGYTEKQRRDFLSEASIMGQFDHPNII 739 Query: 325 QLIGWCDDGGRLVLIYELEPNGSVSDHL 408 L G ++++ E NGS+ L Sbjct: 740 HLEGVVTKSKPVMIVTEYMENGSLDTFL 767
>EPHA8_MOUSE (O09127) Ephrin type-A receptor 8 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) Length = 1004 Score = 47.8 bits (112), Expect = 1e-05 Identities = 35/120 (29%), Positives = 59/120 (49%), Gaps = 13/120 (10%) Frame = +1 Query: 97 ARKFSYSELVAATDNFSRD---------RKIGKGSFGDVYRGLLPMPDLREV--AVKEMR 243 A +Y E A +F+R+ + IG G G+V G L +P R+V A+K ++ Sbjct: 610 AEPHTYEEPGRAGRSFTREIEASRIHIEKIIGSGESGEVCYGRLQVPGQRDVPVAIKALK 669 Query: 244 QPTLKRNRKNYVHEIETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHL--HDG 417 +R R++++ E + Q H N+++L G G +++ E NGS+ L HDG Sbjct: 670 AGYTERQRQDFLSEAAIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDAFLRTHDG 729
>TRK1_LYMST (O76997) Putative neurotrophin receptor LTRK 1 precursor (EC| 2.7.10.1) Length = 794 Score = 47.8 bits (112), Expect = 1e-05 Identities = 26/93 (27%), Positives = 48/93 (51%), Gaps = 4/93 (4%) Frame = +1 Query: 154 RKIGKGSFGDVYRG----LLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNL 321 R IG+G+FG V+ G L+ + VAVK ++ ++++ E E L + H N+ Sbjct: 508 RVIGEGAFGRVFLGTCAHLIQKNEFAIVAVKTLKGSCSDSLKRDFEREAEMLATIEHANI 567 Query: 322 LQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGG 420 + G C + + ++I+E NG ++ +L G Sbjct: 568 VTFYGVCTESDQWMMIFEFMENGDLNKYLRMHG 600
>PTK6_HUMAN (Q13882) Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor| kinase) (Tyrosine-protein kinase BRK) Length = 451 Score = 47.8 bits (112), Expect = 1e-05 Identities = 31/93 (33%), Positives = 52/93 (55%) Frame = +1 Query: 136 DNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHK 315 + F+ RK+G G FG+V+ GL D +VA+K + + L +++ EI+ + +LRHK Sbjct: 189 EEFTLCRKLGSGYFGEVFEGL--WKDRVQVAIKVISRDNL-LHQQMLQSEIQAMKKLRHK 245 Query: 316 NLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHD 414 ++L L G + +I EL GS+ + L D Sbjct: 246 HILALYAVVSVGDPVYIITELMAKGSLLELLRD 278
>SRMS_MOUSE (Q62270) Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70)| Length = 496 Score = 47.8 bits (112), Expect = 1e-05 Identities = 34/100 (34%), Positives = 55/100 (55%), Gaps = 2/100 (2%) Frame = +1 Query: 154 RKIGKGSFGDVYRGLL--PMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQ 327 RK+G+G FG+V+ GL +P VAVK ++ +K + EIE L LRH+ L++ Sbjct: 238 RKLGEGFFGEVWEGLWLGSIP----VAVKVIKSADMKL--ADLTKEIEALKSLRHERLIR 291 Query: 328 LIGWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTLTWP 447 L C G + ++ EL G++ +L G + G+ L+ P Sbjct: 292 LHAICSLGEPVYIVTELMGKGNLQVYL--GSSEGKALSLP 329
>TNI3K_MOUSE (Q5GIG6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 833 Score = 47.4 bits (111), Expect = 2e-05 Identities = 30/88 (34%), Positives = 45/88 (51%), Gaps = 3/88 (3%) Frame = +1 Query: 160 IGKGSFGDVYRGLLPMPDLREVAVKEMRQPTL--KRNRKNYVHEIETLCQLRHKNLLQLI 333 IG GSFG VY+G + VA+K R T K + + E+ LCQL H ++Q + Sbjct: 467 IGSGSFGKVYKGRCRN---KIVAIKRYRANTYCSKSDVDMFCREVSILCQLNHPCVVQFV 523 Query: 334 GWC-DDGGRLVLIYELEPNGSVSDHLHD 414 G C DD + ++ + GS+ LH+ Sbjct: 524 GACLDDPSQFAIVTQYISGGSLFSLLHE 551
>EPHB3_CHICK (Q07498) Ephrin type-B receptor 3 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor CEK10) (Fragment) Length = 988 Score = 47.4 bits (111), Expect = 2e-05 Identities = 29/90 (32%), Positives = 48/90 (53%), Gaps = 4/90 (4%) Frame = +1 Query: 160 IGKGSFGDVYRGLLPMPDLRE--VAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLI 333 IG G FG+V RG L +P RE VA+K ++ +R R++++ E + Q H N++ L Sbjct: 629 IGAGEFGEVCRGRLKLPGRREIFVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIHLE 688 Query: 334 GWCDDGGRLVLIYELEPNGSVSD--HLHDG 417 G +++I E N ++ L+DG Sbjct: 689 GVVTKSRPVMIITEFMENCALDSFLRLNDG 718
>ABL_FSVHY (P10447) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 439 Score = 47.4 bits (111), Expect = 2e-05 Identities = 27/102 (26%), Positives = 54/102 (52%) Frame = +1 Query: 109 SYSELVAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEI 288 +Y + + + K+G G +G+VY G+ L VAVK +++ T++ + ++ E Sbjct: 180 NYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLT-VAVKTLKEDTMEV--EEFLKEA 236 Query: 289 ETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHD 414 + +++H NL+QL+G C +I E G++ D+L + Sbjct: 237 AVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRE 278
>ABL1_MOUSE (P00520) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1123 Score = 47.4 bits (111), Expect = 2e-05 Identities = 27/102 (26%), Positives = 54/102 (52%) Frame = +1 Query: 109 SYSELVAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEI 288 +Y + + + K+G G +G+VY G+ L VAVK +++ T++ + ++ E Sbjct: 231 NYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLT-VAVKTLKEDTMEV--EEFLKEA 287 Query: 289 ETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHD 414 + +++H NL+QL+G C +I E G++ D+L + Sbjct: 288 AVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRE 329
>MKNK1_XENTR (Q66JF3) MAP kinase-interacting serine/threonine-protein kinase 1| (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (Mnk1) Length = 417 Score = 47.4 bits (111), Expect = 2e-05 Identities = 27/87 (31%), Positives = 51/87 (58%), Gaps = 1/87 (1%) Frame = +1 Query: 151 DRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLR-HKNLLQ 327 D +G+G++ V +G + + + ++ AVK + + +R E+ETL Q + +KN+L+ Sbjct: 40 DELLGEGAYAKV-QGCVSLQNGKDYAVKIVEKKA-GHSRSRVFREVETLYQCQGNKNILE 97 Query: 328 LIGWCDDGGRLVLIYELEPNGSVSDHL 408 LI +C+D R L++E GS+ H+ Sbjct: 98 LIEFCEDDARFYLVFEKLRGGSILSHI 124
>ABL2_HUMAN (P42684) Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine| leukemia viral oncogene homolog 2) (Tyrosine kinase ARG) Length = 1182 Score = 47.4 bits (111), Expect = 2e-05 Identities = 26/86 (30%), Positives = 50/86 (58%) Frame = +1 Query: 157 KIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLIG 336 K+G G +G+VY G+ L VAVK +++ T++ + ++ E + +++H NL+QL+G Sbjct: 293 KLGGGQYGEVYVGVWKKYSLT-VAVKTLKEDTMEV--EEFLKEAAVMKEIKHPNLVQLLG 349 Query: 337 WCDDGGRLVLIYELEPNGSVSDHLHD 414 C ++ E P G++ D+L + Sbjct: 350 VCTLEPPFYIVTEYMPYGNLLDYLRE 375
>TNI3K_RAT (Q7TQP6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 834 Score = 47.4 bits (111), Expect = 2e-05 Identities = 30/88 (34%), Positives = 45/88 (51%), Gaps = 3/88 (3%) Frame = +1 Query: 160 IGKGSFGDVYRGLLPMPDLREVAVKEMRQPTL--KRNRKNYVHEIETLCQLRHKNLLQLI 333 IG GSFG VY+G + VA+K R T K + + E+ LCQL H ++Q + Sbjct: 468 IGSGSFGKVYKGRCRN---KIVAIKRYRANTYCSKSDVDMFCREVSILCQLNHPCVVQFV 524 Query: 334 GWC-DDGGRLVLIYELEPNGSVSDHLHD 414 G C DD + ++ + GS+ LH+ Sbjct: 525 GACLDDPSQFAIVTQYISGGSLFSLLHE 552
>SRK4_SPOLA (P42690) Tyrosine-protein kinase isoform SRK4 (EC 2.7.10.2)| Length = 506 Score = 47.4 bits (111), Expect = 2e-05 Identities = 29/91 (31%), Positives = 48/91 (52%) Frame = +1 Query: 154 RKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLI 333 R +G G FG+V+ GL VAVK ++ T+ + + ++ E + QLRH L+QL Sbjct: 244 RGLGAGQFGEVWEGL--WNGTTSVAVKTLKPGTM--SIEEFLEEASIMKQLRHPKLIQLY 299 Query: 334 GWCDDGGRLVLIYELEPNGSVSDHLHDGGAS 426 C + ++ EL +GS+ ++L G S Sbjct: 300 AVCTKEEPIYIVTELMKHGSLLEYLRGDGRS 330
>ABL_MLVAB (P00521) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 746 Score = 47.4 bits (111), Expect = 2e-05 Identities = 27/102 (26%), Positives = 54/102 (52%) Frame = +1 Query: 109 SYSELVAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEI 288 +Y + + + K+G G +G+VY G+ L VAVK +++ T++ + ++ E Sbjct: 117 NYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLT-VAVKTLKEDTMEV--EEFLKEA 173 Query: 289 ETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHD 414 + +++H NL+QL+G C +I E G++ D+L + Sbjct: 174 AVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRE 215
>ABL1_HUMAN (P00519) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1130 Score = 47.4 bits (111), Expect = 2e-05 Identities = 27/102 (26%), Positives = 54/102 (52%) Frame = +1 Query: 109 SYSELVAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEI 288 +Y + + + K+G G +G+VY G+ L VAVK +++ T++ + ++ E Sbjct: 231 NYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLT-VAVKTLKEDTMEV--EEFLKEA 287 Query: 289 ETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHD 414 + +++H NL+QL+G C +I E G++ D+L + Sbjct: 288 AVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRE 329
>EPA4A_BRARE (O13148) Ephrin type-A receptor 4a (EC 2.7.10.1) (Tyrosine-protein| kinase receptor ZEK2) (EPH-like kinase 2) (Fragment) Length = 292 Score = 47.0 bits (110), Expect = 3e-05 Identities = 36/107 (33%), Positives = 53/107 (49%), Gaps = 2/107 (1%) Frame = +1 Query: 160 IGKGSFGDVYRGLLPMPDLRE--VAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLI 333 IG G FG+V G L MP RE VA+K ++ + R++++ E + Q H N+++L Sbjct: 1 IGIGEFGEVCSGRLKMPGKREICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIRLE 60 Query: 334 GWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTLTWPQRYNILLGI 474 G +++I E NGS+ L GR T Q IL GI Sbjct: 61 GVVTKCKPVMIITEYMENGSLDAFLRKN--DGR-FTVIQLVGILRGI 104
>EPHB3_MOUSE (P54754) Ephrin type-B receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4) Length = 993 Score = 47.0 bits (110), Expect = 3e-05 Identities = 28/90 (31%), Positives = 49/90 (54%), Gaps = 4/90 (4%) Frame = +1 Query: 160 IGKGSFGDVYRGLLPMPDLRE--VAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLI 333 IG G FG+V RG L +P RE VA+K ++ +R R++++ E + Q H N+++L Sbjct: 634 IGAGEFGEVCRGRLKLPGRREVFVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLE 693 Query: 334 GWCDDGGRLVLIYELEPNGSVSD--HLHDG 417 G ++++ E N ++ L+DG Sbjct: 694 GVVTKSRPVMILTEFMENCALDSFLRLNDG 723
>MKNK1_XENLA (Q9YGW0) MAP kinase-interacting serine/threonine-protein kinase 1| (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (Mnk1) Length = 418 Score = 47.0 bits (110), Expect = 3e-05 Identities = 27/87 (31%), Positives = 51/87 (58%), Gaps = 1/87 (1%) Frame = +1 Query: 151 DRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLR-HKNLLQ 327 D +G+G++ V +G + + + ++ AVK + + +R E+ETL Q + +KN+L+ Sbjct: 40 DELLGEGAYAKV-QGCVSLQNGKDYAVKIVEKKA-GHSRSRVFREVETLYQCQGNKNILE 97 Query: 328 LIGWCDDGGRLVLIYELEPNGSVSDHL 408 LI +C+D R L++E GS+ H+ Sbjct: 98 LIEFCEDDARFYLVFEKLLGGSILSHI 124
>ATG1_KLULA (Q6CSX2) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 831 Score = 46.6 bits (109), Expect = 3e-05 Identities = 26/69 (37%), Positives = 45/69 (65%), Gaps = 2/69 (2%) Frame = +1 Query: 133 TDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNR--KNYVHEIETLCQL 306 T+N+S +++IGKGSF VY+G L + D R +A+K + + LK + +N EI L ++ Sbjct: 18 TENYSVEKEIGKGSFAVVYKG-LSLRDGRNIAIKAVSRSKLKNKKLLENLEVEIAILKKI 76 Query: 307 RHKNLLQLI 333 +H +++ LI Sbjct: 77 KHPHIVGLI 85
>ABL1_CAEEL (P03949) Tyrosine-protein kinase abl-1 (EC 2.7.10.2)| Length = 1224 Score = 46.6 bits (109), Expect = 3e-05 Identities = 30/100 (30%), Positives = 50/100 (50%), Gaps = 7/100 (7%) Frame = +1 Query: 130 ATDNFSRDR-------KIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEI 288 A D + DR K+G G +GDVY G D +AVK +++ + + ++ E Sbjct: 300 APDEWELDRSEIIMHNKLGGGQYGDVYEGYWKRHDCT-IAVKALKEDAMPLHE--FLAEA 356 Query: 289 ETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHL 408 + L HKNL++L+G C +I E NG++ ++L Sbjct: 357 AIMKDLHHKNLVRLLGVCTHEAPFYIITEFMCNGNLLEYL 396
>LET23_CAEEL (P24348) Receptor tyrosine-protein kinase let-23 precursor (EC| 2.7.10.1) (Lethal protein 23) Length = 1367 Score = 46.6 bits (109), Expect = 3e-05 Identities = 31/92 (33%), Positives = 51/92 (55%), Gaps = 6/92 (6%) Frame = +1 Query: 151 DRKIGKGSFGDVYRGLLPMPDLREV----AVKEMRQPTLKRNRKNYVHEIETLCQLRHKN 318 D+K+G G+FG V+ G+ + V A+K + T + + E + +LRH N Sbjct: 932 DKKLGAGAFGTVFAGIYYPKRAKNVKIPVAIKVFQ--TDQSQTDEMLEEATNMFRLRHDN 989 Query: 319 LLQLIGWC--DDGGRLVLIYELEPNGSVSDHL 408 LL++IG+C DDG ++V IY P G++ + L Sbjct: 990 LLKIIGFCMHDDGLKIVTIY--RPLGNLQNFL 1019
>ULK1_MOUSE (O70405) Serine/threonine-protein kinase ULK1 (EC 2.7.11.1)| (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1) Length = 1051 Score = 46.6 bits (109), Expect = 3e-05 Identities = 28/90 (31%), Positives = 49/90 (54%) Frame = +1 Query: 142 FSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNL 321 FSR IG G+F V++G EVAVK + + L +++ EI+ L +L+H+N+ Sbjct: 16 FSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLLGKEIKILKELKHENI 75 Query: 322 LQLIGWCDDGGRLVLIYELEPNGSVSDHLH 411 + L + + + L+ E G ++D+LH Sbjct: 76 VALYDFQEMANSVYLVMEYCNGGDLADYLH 105
>ABL_DROME (P00522) Tyrosine-protein kinase Abl (EC 2.7.10.2) (Abelson| protein) (D-ash) Length = 1620 Score = 46.6 bits (109), Expect = 3e-05 Identities = 27/88 (30%), Positives = 47/88 (53%) Frame = +1 Query: 157 KIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLIG 336 K+G G +G+VY + VAVK +++ T+ K+++ E + +++H NL+QLIG Sbjct: 376 KLGGGQYGEVYEAVWKRYG-NTVAVKTLKEDTMAL--KDFLEEAAIMKEMKHPNLVQLIG 432 Query: 337 WCDDGGRLVLIYELEPNGSVSDHLHDGG 420 C +I E +G++ D L G Sbjct: 433 VCTREPPFYIITEFMSHGNLLDFLRSAG 460
>ULK1_HUMAN (O75385) Serine/threonine-protein kinase ULK1 (EC 2.7.11.1)| (Unc-51-like kinase 1) Length = 1050 Score = 46.6 bits (109), Expect = 3e-05 Identities = 28/90 (31%), Positives = 49/90 (54%) Frame = +1 Query: 142 FSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNL 321 FSR IG G+F V++G EVAVK + + L +++ EI+ L +L+H+N+ Sbjct: 16 FSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLLGKEIKILKELKHENI 75 Query: 322 LQLIGWCDDGGRLVLIYELEPNGSVSDHLH 411 + L + + + L+ E G ++D+LH Sbjct: 76 VALYDFQEMANSVYLVMEYCNGGDLADYLH 105
>EPHB3_HUMAN (P54753) Ephrin type-B receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor HEK-2) Length = 998 Score = 46.2 bits (108), Expect = 4e-05 Identities = 28/90 (31%), Positives = 48/90 (53%), Gaps = 4/90 (4%) Frame = +1 Query: 160 IGKGSFGDVYRGLLPMPDLREV--AVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLI 333 IG G FG+V RG L P REV A+K ++ +R R++++ E + Q H N+++L Sbjct: 639 IGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLE 698 Query: 334 GWCDDGGRLVLIYELEPNGSVSD--HLHDG 417 G ++++ E N ++ L+DG Sbjct: 699 GVVTKSRPVMILTEFMENCALDSFLRLNDG 728
>MUSK_HUMAN (O15146) Muscle, skeletal receptor tyrosine protein kinase| precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK) Length = 869 Score = 46.2 bits (108), Expect = 4e-05 Identities = 26/95 (27%), Positives = 50/95 (52%), Gaps = 4/95 (4%) Frame = +1 Query: 136 DNFSRDRKIGKGSFGDVYR----GLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQ 303 +N R IG+G+FG V++ GLLP VAVK +++ + ++ E + + Sbjct: 573 NNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAE 632 Query: 304 LRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHL 408 + N+++L+G C G + L++E G +++ L Sbjct: 633 FDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFL 667
>MUSK_RAT (Q62838) Muscle, skeletal receptor tyrosine protein kinase| precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK) Length = 868 Score = 46.2 bits (108), Expect = 4e-05 Identities = 26/95 (27%), Positives = 50/95 (52%), Gaps = 4/95 (4%) Frame = +1 Query: 136 DNFSRDRKIGKGSFGDVYR----GLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQ 303 +N R IG+G+FG V++ GLLP VAVK +++ + ++ E + + Sbjct: 572 NNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAE 631 Query: 304 LRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHL 408 + N+++L+G C G + L++E G +++ L Sbjct: 632 FDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFL 666
>MUSK_MOUSE (Q61006) Muscle, skeletal receptor tyrosine protein kinase| precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK) Length = 868 Score = 46.2 bits (108), Expect = 4e-05 Identities = 26/95 (27%), Positives = 50/95 (52%), Gaps = 4/95 (4%) Frame = +1 Query: 136 DNFSRDRKIGKGSFGDVYR----GLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQ 303 +N R IG+G+FG V++ GLLP VAVK +++ + ++ E + + Sbjct: 572 NNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAE 631 Query: 304 LRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHL 408 + N+++L+G C G + L++E G +++ L Sbjct: 632 FDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFL 666
>ARK1_SCHPO (O59790) Serine/threonine-protein kinase ark1 (EC 2.7.11.1)| (Aurora-related kinase 1) Length = 355 Score = 46.2 bits (108), Expect = 4e-05 Identities = 32/91 (35%), Positives = 44/91 (48%), Gaps = 2/91 (2%) Frame = +1 Query: 142 FSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNR--KNYVHEIETLCQLRHK 315 F + +GKG FG VY VA+K + + L +++ K EIE LRHK Sbjct: 89 FEIGKPLGKGKFGRVYLAKEKKTGFI-VALKTLHKSELVQSKIEKQVRREIEIQSNLRHK 147 Query: 316 NLLQLIGWCDDGGRLVLIYELEPNGSVSDHL 408 N+L+L G D R+ LI E G + HL Sbjct: 148 NILRLYGHFHDEKRIYLILEFAGRGELYQHL 178
>CDPK2_PLAFK (O15865) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (PfCDPK2)| Length = 512 Score = 46.2 bits (108), Expect = 4e-05 Identities = 28/96 (29%), Positives = 54/96 (56%) Frame = +1 Query: 136 DNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHK 315 D + D K+G+G++G VY+G+ + + + A+KE ++ LK N + EIE + +L H Sbjct: 69 DKYIIDEKLGQGTYGCVYKGIDKVTN-QLYAIKEEKKDRLK-NINRFFQEIEIMKKLDHP 126 Query: 316 NLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGA 423 N+++L ++ + LI EL + D + + G+ Sbjct: 127 NIVKLYETYENDNYIYLIMELCSGRELFDSIIENGS 162
>EPA4A_XENLA (Q91845) Ephrin type-A receptor 4-A precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK-1) (xSEK-1) Length = 986 Score = 46.2 bits (108), Expect = 4e-05 Identities = 35/110 (31%), Positives = 54/110 (49%), Gaps = 2/110 (1%) Frame = +1 Query: 151 DRKIGKGSFGDVYRGLLPMPDLRE--VAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLL 324 ++ IG G FG+V G L +P RE VA+K ++ + R++++ E + Q H N++ Sbjct: 623 EKVIGVGEFGEVCSGRLKVPGKREIYVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNII 682 Query: 325 QLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTLTWPQRYNILLGI 474 L G +++I E NGS+ L GR T Q IL GI Sbjct: 683 HLEGVVTKCKPVMIITEYMENGSLDAFLRKN--DGR-FTVIQLVGILRGI 729
>CDPK2_PLAF7 (Q8ICR0) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (PfCDPK2)| Length = 508 Score = 46.2 bits (108), Expect = 4e-05 Identities = 28/96 (29%), Positives = 54/96 (56%) Frame = +1 Query: 136 DNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHK 315 D + D K+G+G++G VY+G+ + + + A+KE ++ LK N + EIE + +L H Sbjct: 69 DKYIIDEKLGQGTYGCVYKGIDKVTN-QLYAIKEEKKDRLK-NINRFFQEIEIMKKLDHP 126 Query: 316 NLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGA 423 N+++L ++ + LI EL + D + + G+ Sbjct: 127 NIVKLYETYENDNYIYLIMELCSGRELFDSIIENGS 162
>TNI3K_HUMAN (Q59H18) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 936 Score = 45.8 bits (107), Expect = 6e-05 Identities = 29/88 (32%), Positives = 45/88 (51%), Gaps = 3/88 (3%) Frame = +1 Query: 160 IGKGSFGDVYRGLLPMPDLREVAVKEMRQPTL--KRNRKNYVHEIETLCQLRHKNLLQLI 333 IG GSFG VY+G + VA+K R T K + + E+ LCQL H ++Q + Sbjct: 570 IGSGSFGKVYKGRCRN---KIVAIKRYRANTYCSKSDVDMFCREVSILCQLNHPCVIQFV 626 Query: 334 GWC-DDGGRLVLIYELEPNGSVSDHLHD 414 G C +D + ++ + GS+ LH+ Sbjct: 627 GACLNDPSQFAIVTQYISGGSLFSLLHE 654
>TNI3K_PONPY (Q5RF15) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) Length = 617 Score = 45.8 bits (107), Expect = 6e-05 Identities = 29/88 (32%), Positives = 45/88 (51%), Gaps = 3/88 (3%) Frame = +1 Query: 160 IGKGSFGDVYRGLLPMPDLREVAVKEMRQPTL--KRNRKNYVHEIETLCQLRHKNLLQLI 333 IG GSFG VY+G + VA+K R T K + + E+ LCQL H ++Q + Sbjct: 468 IGSGSFGKVYKGRCRN---KIVAIKRYRANTYCSKSDVDMFCREVSILCQLNHPCVIQFV 524 Query: 334 GWC-DDGGRLVLIYELEPNGSVSDHLHD 414 G C +D + ++ + GS+ LH+ Sbjct: 525 GACLNDPSQFAIVTQYISGGSLFSLLHE 552
>RIPK2_HUMAN (O43353) Receptor-interacting serine/threonine-protein kinase 2 (EC| 2.7.11.1) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (CARD-containing interleukin-1 beta-converting enzyme-associated kinase) (CARD-containi Length = 540 Score = 45.8 bits (107), Expect = 6e-05 Identities = 28/84 (33%), Positives = 45/84 (53%), Gaps = 2/84 (2%) Frame = +1 Query: 220 EVAVKEMR--QPTLKRNRKNYVHEIETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGS 393 +VAVK + P L RK+ + E E L + R +L ++G C++ L ++ E PNGS Sbjct: 43 QVAVKHLHIHTPLLDSERKDVLREAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGS 102 Query: 394 VSDHLHDGGASGRTLTWPQRYNIL 465 +++ LH + WP R+ IL Sbjct: 103 LNELLH-RKTEYPDVAWPLRFRIL 125
>EPHA2_HUMAN (P29317) Ephrin type-A receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) Length = 976 Score = 45.8 bits (107), Expect = 6e-05 Identities = 25/93 (26%), Positives = 50/93 (53%), Gaps = 3/93 (3%) Frame = +1 Query: 145 SRDRKIGKGSFGDVYRGLLPMPDLRE---VAVKEMRQPTLKRNRKNYVHEIETLCQLRHK 315 +R + IG G FG+VY+G+L ++ VA+K ++ ++ R +++ E + Q H Sbjct: 614 TRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAGYTEKQRVDFLGEAGIMGQFSHH 673 Query: 316 NLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHD 414 N+++L G +++I E NG++ L + Sbjct: 674 NIIRLEGVISKYKPMMIITEYMENGALDKFLRE 706
>KPK2_PLAFK (Q02595) Probable serine/threonine-protein kinase 2 (EC 2.7.11.1)| Length = 510 Score = 45.4 bits (106), Expect = 7e-05 Identities = 30/90 (33%), Positives = 50/90 (55%) Frame = +1 Query: 151 DRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQL 330 ++KIGKGSF Y G + R V VKE+ + +K + N EIE L ++ HK +++L Sbjct: 114 NKKIGKGSFSTAYIGTNILYGNR-VVVKEVDKSKVKES--NVYTEIEVLRKVMHKYIIKL 170 Query: 331 IGWCDDGGRLVLIYELEPNGSVSDHLHDGG 420 I + G + L+ E G + ++L++ G Sbjct: 171 ISAYEQEGFVYLVLEYLKGGELFEYLNNNG 200
>JAK2_HUMAN (O60674) Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2)| (JAK-2) Length = 1132 Score = 45.4 bits (106), Expect = 7e-05 Identities = 33/90 (36%), Positives = 52/90 (57%), Gaps = 5/90 (5%) Frame = +1 Query: 154 RKIGKGSFGDVYRGLL-PMPDL--REVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLL 324 +++GKG+FG V P+ D VAVK+++ T + + +++ EIE L L+H N++ Sbjct: 853 QQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHST-EEHLRDFEREIEILKSLQHDNIV 911 Query: 325 QLIGWCDDGGR--LVLIYELEPNGSVSDHL 408 + G C GR L LI E P GS+ D+L Sbjct: 912 KYKGVCYSAGRRNLKLIMEYLPYGSLRDYL 941 Score = 32.0 bits (71), Expect = 0.83 Identities = 21/91 (23%), Positives = 43/91 (47%), Gaps = 5/91 (5%) Frame = +1 Query: 151 DRKIGKGSFGDVYRGLL-PMPDLREVAVKEMRQPTLKRNRKNYVHEI----ETLCQLRHK 315 + +G+G+F +++G+ + D ++ E+ L + +NY + +L HK Sbjct: 548 NESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMSKLSHK 607 Query: 316 NLLQLIGWCDDGGRLVLIYELEPNGSVSDHL 408 +L+ G C G +L+ E GS+ +L Sbjct: 608 HLVLNYGVCVCGDENILVQEFVKFGSLDTYL 638
>EPA4B_XENLA (Q91694) Ephrin type-A receptor 4-B precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor PAG) (Pagliaccio) Length = 985 Score = 45.4 bits (106), Expect = 7e-05 Identities = 27/88 (30%), Positives = 46/88 (52%), Gaps = 2/88 (2%) Frame = +1 Query: 151 DRKIGKGSFGDVYRGLLPMPDLRE--VAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLL 324 ++ IG G FG+V G L +P RE VA+K ++ + R++++ E + Q H N++ Sbjct: 623 EKVIGVGEFGEVCSGRLKVPGKREIYVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNII 682 Query: 325 QLIGWCDDGGRLVLIYELEPNGSVSDHL 408 L G +++I E NGS+ L Sbjct: 683 HLEGVVTKCKPVMIITEYMENGSLDAFL 710
>EPHA4_MOUSE (Q03137) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK) (MPK-3) Length = 986 Score = 45.4 bits (106), Expect = 7e-05 Identities = 27/88 (30%), Positives = 46/88 (52%), Gaps = 2/88 (2%) Frame = +1 Query: 151 DRKIGKGSFGDVYRGLLPMPDLRE--VAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLL 324 ++ IG G FG+V G L +P RE VA+K ++ + R++++ E + Q H N++ Sbjct: 624 EKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNII 683 Query: 325 QLIGWCDDGGRLVLIYELEPNGSVSDHL 408 L G +++I E NGS+ L Sbjct: 684 HLEGVVTKCKPVMIITEYMENGSLDAFL 711
>EPHA4_HUMAN (P54764) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8) Length = 986 Score = 45.4 bits (106), Expect = 7e-05 Identities = 27/88 (30%), Positives = 46/88 (52%), Gaps = 2/88 (2%) Frame = +1 Query: 151 DRKIGKGSFGDVYRGLLPMPDLRE--VAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLL 324 ++ IG G FG+V G L +P RE VA+K ++ + R++++ E + Q H N++ Sbjct: 624 EKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNII 683 Query: 325 QLIGWCDDGGRLVLIYELEPNGSVSDHL 408 L G +++I E NGS+ L Sbjct: 684 HLEGVVTKCKPVMIITEYMENGSLDAFL 711
>EPHA4_CHICK (Q07496) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK8) Length = 986 Score = 45.4 bits (106), Expect = 7e-05 Identities = 27/88 (30%), Positives = 46/88 (52%), Gaps = 2/88 (2%) Frame = +1 Query: 151 DRKIGKGSFGDVYRGLLPMPDLRE--VAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLL 324 ++ IG G FG+V G L +P RE VA+K ++ + R++++ E + Q H N++ Sbjct: 624 EKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNII 683 Query: 325 QLIGWCDDGGRLVLIYELEPNGSVSDHL 408 L G +++I E NGS+ L Sbjct: 684 HLEGVVTKCKPVMIITEYMENGSLDAFL 711
>XMRK_XIPMA (P13388) Melanoma receptor tyrosine-protein kinase precursor (EC| 2.7.10.1) Length = 1167 Score = 45.4 bits (106), Expect = 7e-05 Identities = 28/93 (30%), Positives = 50/93 (53%), Gaps = 4/93 (4%) Frame = +1 Query: 142 FSRDRKIGKGSFGDVYRGLLPMPDLRE----VAVKEMRQPTLKRNRKNYVHEIETLCQLR 309 F +DR +G G+FG VY+GL PD VA+K +R+ T + + + E + + Sbjct: 710 FKKDRVLGSGAFGTVYKGLW-NPDGENIRIPVAIKVLREATSPKVNQEVLDEAYVMASVD 768 Query: 310 HKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHL 408 H ++ +L+G C + L+ +L P G + D++ Sbjct: 769 HPHVCRLLGICLTSA-VQLVTQLMPYGCLLDYV 800
>AURKC_HUMAN (Q9UQB9) Serine/threonine-protein kinase 13 (EC 2.7.11.1)| (Aurora/Ipl1/Eg2 protein 2) (Aurora/Ipl1-related kinase 3) (Aurora-C) Length = 309 Score = 45.4 bits (106), Expect = 7e-05 Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 2/93 (2%) Frame = +1 Query: 136 DNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYV--HEIETLCQLR 309 D+F R +GKG FG+VY L VA+K + + +++ + EIE L+ Sbjct: 41 DDFEIGRPLGKGKFGNVYLARLKESHFI-VALKVLFKSQIEKEGLEHQLRREIEIQAHLQ 99 Query: 310 HKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHL 408 H N+L+L + D R+ LI E P G + L Sbjct: 100 HPNILRLYNYFHDARRVYLILEYAPRGELYKEL 132
>EPHA5_CHICK (P54755) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK7) Length = 1013 Score = 45.4 bits (106), Expect = 7e-05 Identities = 26/88 (29%), Positives = 46/88 (52%), Gaps = 2/88 (2%) Frame = +1 Query: 151 DRKIGKGSFGDVYRGLLPMPDLRE--VAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLL 324 +R IG G FG+V G L + RE VA+K ++ ++ R++++ E + Q H N++ Sbjct: 654 ERVIGAGEFGEVCSGRLKLQGKREFPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNII 713 Query: 325 QLIGWCDDGGRLVLIYELEPNGSVSDHL 408 L G ++++ E NGS+ L Sbjct: 714 HLEGVVTKSKPVMIVTEYMENGSLDTFL 741
>CC2H1_TRYCO (P54664) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| Length = 301 Score = 45.4 bits (106), Expect = 7e-05 Identities = 28/79 (35%), Positives = 46/79 (58%), Gaps = 1/79 (1%) Frame = +1 Query: 142 FSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRK-NYVHEIETLCQLRHKN 318 + R KIG+GS+G VYR D+ VA+K +R +++ + EI L +LRH+N Sbjct: 5 YQRLEKIGEGSYGVVYRARDITTDV-IVALKRIRLESVEEGVPCTAIREISILKELRHEN 63 Query: 319 LLQLIGWCDDGGRLVLIYE 375 +++L+ C RL L++E Sbjct: 64 IVRLLDVCHSENRLNLVFE 82
>M3K3_HUMAN (Q99759) Mitogen-activated protein kinase kinase kinase 3 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3) Length = 626 Score = 45.4 bits (106), Expect = 7e-05 Identities = 39/137 (28%), Positives = 63/137 (45%), Gaps = 6/137 (4%) Frame = +1 Query: 82 NCLQVARKFSYSELVAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMR----QP 249 N L V + ++ +A N+ R + +G+G+FG VY + RE+A K+++ P Sbjct: 342 NALSVQERNVPTKSPSAPINWRRGKLLGQGAFGRVYL-CYDVDTGRELASKQVQFDPDSP 400 Query: 250 TLKRNRKNYVHEIETLCQLRHKNLLQLIGWCDDGGR--LVLIYELEPNGSVSDHLHDGGA 423 + EI+ L L+H+ ++Q G D L + E P GSV D L GA Sbjct: 401 ETSKEVSALECEIQLLKNLQHERIVQYYGCLRDRAEKTLTIFMEYMPGGSVKDQLKAYGA 460 Query: 424 SGRTLTWPQRYNILLGI 474 ++T IL G+ Sbjct: 461 LTESVTRKYTRQILEGM 477
>ROR2_DROME (Q9V6K3) Tyrosine-protein kinase transmembrane receptor Ror2| precursor (EC 2.7.10.1) (Neurospecific receptor tyrosine kinase) Length = 724 Score = 45.4 bits (106), Expect = 7e-05 Identities = 26/89 (29%), Positives = 49/89 (55%), Gaps = 4/89 (4%) Frame = +1 Query: 154 RKIGKGSFGDVYRGLLP--MPDLRE--VAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNL 321 R +G+G+FG V++ P +PD + VAVK ++ + + ++ E L + H N+ Sbjct: 445 RSLGQGAFGRVFQARAPGLVPDQEDLLVAVKMLKDDASDQMQMDFEREACLLAEFDHPNI 504 Query: 322 LQLIGWCDDGGRLVLIYELEPNGSVSDHL 408 ++L+G C G + L++E G +S+ L Sbjct: 505 VRLLGVCALGRPMCLLFEYMAPGDLSEFL 533
>EPHB5_CHICK (Q07497) Ephrin type-B receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase CEK9) Length = 1002 Score = 45.1 bits (105), Expect = 1e-04 Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 2/85 (2%) Frame = +1 Query: 160 IGKGSFGDVYRGLLPMPDLRE--VAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLI 333 IG G FG+V G L P RE VA+K ++ R+ ++ E + Q H N++ L Sbjct: 643 IGSGEFGEVCFGRLKHPGKREYTVAIKTLKSGYTDEQRREFLSEASIMGQFEHPNVIHLE 702 Query: 334 GWCDDGGRLVLIYELEPNGSVSDHL 408 G ++++ E NGS+ L Sbjct: 703 GVVTKSRPVMIVTEFMENGSLDSFL 727
>JAK2_RAT (Q62689) Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2)| (JAK-2) Length = 1132 Score = 45.1 bits (105), Expect = 1e-04 Identities = 33/90 (36%), Positives = 52/90 (57%), Gaps = 5/90 (5%) Frame = +1 Query: 154 RKIGKGSFGDVYRGLL-PMPDL--REVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLL 324 +++GKG+FG V P+ D VAVK+++ T + + +++ EIE L L+H N++ Sbjct: 853 QQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHST-EEHLRDFEREIEILKSLQHDNIV 911 Query: 325 QLIGWCDDGGR--LVLIYELEPNGSVSDHL 408 + G C GR L LI E P GS+ D+L Sbjct: 912 KYKGVCYSAGRRNLRLIMEYLPYGSLRDYL 941 Score = 33.1 bits (74), Expect = 0.37 Identities = 22/91 (24%), Positives = 43/91 (47%), Gaps = 5/91 (5%) Frame = +1 Query: 151 DRKIGKGSFGDVYRGLL-PMPDLREVAVKEMRQPTLKRNRKNYVHEI----ETLCQLRHK 315 + +G+G+F +++G+ + D ++ E+ L + +NY + QL HK Sbjct: 548 NESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMSQLSHK 607 Query: 316 NLLQLIGWCDDGGRLVLIYELEPNGSVSDHL 408 +L+ G C G +L+ E GS+ +L Sbjct: 608 HLVLNYGVCVCGEENILVQEFVKFGSLDTYL 638
>EPHA2_MOUSE (Q03145) Ephrin type-A receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2) Length = 977 Score = 45.1 bits (105), Expect = 1e-04 Identities = 25/93 (26%), Positives = 48/93 (51%), Gaps = 3/93 (3%) Frame = +1 Query: 145 SRDRKIGKGSFGDVYRGLLPMPDLRE---VAVKEMRQPTLKRNRKNYVHEIETLCQLRHK 315 +R + IG G FG+VY+G L ++ VA+K ++ ++ R +++ E + Q H Sbjct: 615 ARQKVIGAGEFGEVYKGTLKASSGKKEIPVAIKTLKAGYTEKQRVDFLSEASIMGQFSHH 674 Query: 316 NLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHD 414 N++ L G +++I E NG++ L + Sbjct: 675 NIIPLEGVVSKYKPMMIITEYMENGALDKFLRE 707
>JAK2_MOUSE (Q62120) Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2)| (JAK-2) Length = 1129 Score = 45.1 bits (105), Expect = 1e-04 Identities = 33/90 (36%), Positives = 52/90 (57%), Gaps = 5/90 (5%) Frame = +1 Query: 154 RKIGKGSFGDVYRGLL-PMPDL--REVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLL 324 +++GKG+FG V P+ D VAVK+++ T + + +++ EIE L L+H N++ Sbjct: 853 QQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHST-EEHLRDFEREIEILKSLQHDNIV 911 Query: 325 QLIGWCDDGGR--LVLIYELEPNGSVSDHL 408 + G C GR L LI E P GS+ D+L Sbjct: 912 KYKGVCYSAGRRNLRLIMEYLPYGSLRDYL 941 Score = 33.1 bits (74), Expect = 0.37 Identities = 22/91 (24%), Positives = 43/91 (47%), Gaps = 5/91 (5%) Frame = +1 Query: 151 DRKIGKGSFGDVYRGLL-PMPDLREVAVKEMRQPTLKRNRKNYVHEI----ETLCQLRHK 315 + +G+G+F +++G+ + D ++ E+ L + +NY + QL HK Sbjct: 548 NESLGQGTFTKIFKGVRREVGDYGQLHKTEVLLKVLDKAHRNYSESFFEAASMMSQLSHK 607 Query: 316 NLLQLIGWCDDGGRLVLIYELEPNGSVSDHL 408 +L+ G C G +L+ E GS+ +L Sbjct: 608 HLVLNYGVCVCGEENILVQEFVKFGSLDTYL 638
>AURKB_MOUSE (O70126) Serine/threonine-protein kinase 12 (EC 2.7.11.1)| (Aurora-related kinase 2) (Serine/threonine-protein kinase 5) (STK-1) (Aurora-B) Length = 345 Score = 45.1 bits (105), Expect = 1e-04 Identities = 31/93 (33%), Positives = 45/93 (48%), Gaps = 2/93 (2%) Frame = +1 Query: 136 DNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYV--HEIETLCQLR 309 DNF R +GKG FG+VY VA+K + + +++ + EIE L+ Sbjct: 80 DNFEIGRPLGKGKFGNVYLAREKKSRFI-VALKILFKSQIEKEGVEHQLRREIEIQAHLK 138 Query: 310 HKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHL 408 H N+LQL + D R+ LI E P G + L Sbjct: 139 HPNILQLYNYFYDQQRIYLILEYAPRGELYKEL 171
>SRC64_DROME (P00528) Tyrosine-protein kinase Src64B (EC 2.7.10.2) (Dsrc64)| Length = 552 Score = 45.1 bits (105), Expect = 1e-04 Identities = 26/88 (29%), Positives = 47/88 (53%) Frame = +1 Query: 154 RKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLI 333 RK+G+G+FG+V+ G + +VAVK +R+ T+ + ++ E + + RH L+ L Sbjct: 288 RKLGRGNFGEVFYG--KWRNSIDVAVKTLREGTM--STAAFLQEAAIMKKFRHNRLVALY 343 Query: 334 GWCDDGGRLVLIYELEPNGSVSDHLHDG 417 C + ++ E GS+ D L +G Sbjct: 344 AVCSQEEPIYIVQEYMSKGSLLDFLREG 371
>M3K3_MOUSE (Q61084) Mitogen-activated protein kinase kinase kinase 3 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3) Length = 626 Score = 45.1 bits (105), Expect = 1e-04 Identities = 39/137 (28%), Positives = 63/137 (45%), Gaps = 6/137 (4%) Frame = +1 Query: 82 NCLQVARKFSYSELVAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMR----QP 249 N L V + ++ +A N+ R + +G+G+FG VY + RE+A K+++ P Sbjct: 342 NALTVQERNVPTKSPSAPINWRRGKLLGQGAFGRVYL-CYDVDTGRELASKQVQFDPDSP 400 Query: 250 TLKRNRKNYVHEIETLCQLRHKNLLQLIGWCDDGGR--LVLIYELEPNGSVSDHLHDGGA 423 + EI+ L L+H+ ++Q G D L + E P GSV D L GA Sbjct: 401 ETSKEVSALECEIQLLKNLQHERIVQYYGCLRDRAEKILTIFMEYMPGGSVKDQLKAYGA 460 Query: 424 SGRTLTWPQRYNILLGI 474 ++T IL G+ Sbjct: 461 LTESVTRKYTRQILEGM 477
>STK6_HUMAN (O14965) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1) (Aurora-related kinase 1) (hARK1) (Aurora-A) (Breast-tumor-amplified kinase) Length = 403 Score = 45.1 bits (105), Expect = 1e-04 Identities = 30/91 (32%), Positives = 47/91 (51%), Gaps = 2/91 (2%) Frame = +1 Query: 130 ATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYV--HEIETLCQ 303 A ++F R +GKG FG+VY +A+K + + L++ + E+E Sbjct: 129 ALEDFEIGRPLGKGKFGNVYLAREKQSKFI-LALKVLFKAQLEKAGVEHQLRREVEIQSH 187 Query: 304 LRHKNLLQLIGWCDDGGRLVLIYELEPNGSV 396 LRH N+L+L G+ D R+ LI E P G+V Sbjct: 188 LRHPNILRLYGYFHDATRVYLILEYAPLGTV 218
>IGF1R_RAT (P24062) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1370 Score = 44.7 bits (104), Expect = 1e-04 Identities = 27/102 (26%), Positives = 52/102 (50%), Gaps = 5/102 (4%) Frame = +1 Query: 118 ELVAATDNFSRDRKIGKGSFGDVYRGLLP-----MPDLREVAVKEMRQPTLKRNRKNYVH 282 E A + + +R++G+GSFG VY G+ P+ R VA+K + + R R +++ Sbjct: 992 EWEVAREKITMNRELGQGSFGMVYEGVAKGVVKDEPETR-VAIKTVNEAASMRERIEFLN 1050 Query: 283 EIETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHL 408 E + + ++++L+G G ++I EL G + +L Sbjct: 1051 EASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYL 1092
>M3K2_MOUSE (Q61083) Mitogen-activated protein kinase kinase kinase 2 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2) Length = 619 Score = 44.7 bits (104), Expect = 1e-04 Identities = 42/147 (28%), Positives = 63/147 (42%), Gaps = 6/147 (4%) Frame = +1 Query: 52 IKRPTRCLDGNCLQVARKFSYSELVAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAV 231 I+R +D L V S A N+ + +G+G+FG VY + RE+AV Sbjct: 326 IRRRGSDIDNPTLTVTDISPPSRSPRAPTNWRLGKLLGQGAFGRVYL-CYDVDTGRELAV 384 Query: 232 KEMR----QPTLKRNRKNYVHEIETLCQLRHKNLLQLIGWCDDGGR--LVLIYELEPNGS 393 K+++ P + EI+ L L H+ ++Q G D L + EL P GS Sbjct: 385 KQVQFNPESPETSKEVNALECEIQLLKNLLHERIVQYYGCLRDPQEKTLSIFMELSPGGS 444 Query: 394 VSDHLHDGGASGRTLTWPQRYNILLGI 474 + D L GA +T IL G+ Sbjct: 445 IKDQLKAYGALTENVTRKYTRQILEGV 471
>EPHB3_XENLA (Q91735) Ephrin type-B receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TCK) Length = 974 Score = 44.7 bits (104), Expect = 1e-04 Identities = 29/112 (25%), Positives = 55/112 (49%), Gaps = 11/112 (9%) Frame = +1 Query: 106 FSYSELVAATDNFSRD---------RKIGKGSFGDVYRGLLPMPDLRE--VAVKEMRQPT 252 F+Y + A +F+++ IG G FG+V RG L RE VA+K ++ Sbjct: 588 FTYEDPNEAVRDFAKEIDISCVKIEEVIGAGEFGEVCRGKLKQAGRREQFVAIKTLKAGY 647 Query: 253 LKRNRKNYVHEIETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHL 408 ++ R++++ E + Q H N+++L G ++++ E NG++ L Sbjct: 648 TEQQRRDFLGEASIMGQFDHPNIIRLEGVVTRSRPVMILTEFMENGALDSFL 699
>YSK4_HUMAN (Q56UN5) SPS1/STE20-related protein kinase YSK4 (EC 2.7.11.1)| (Regulated in COPD, protein kinase) Length = 1328 Score = 44.7 bits (104), Expect = 1e-04 Identities = 27/108 (25%), Positives = 50/108 (46%), Gaps = 3/108 (2%) Frame = +1 Query: 160 IGKGSFGDVYRGLLPMPDL---REVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQL 330 +GKG++G VY GL L ++VA+ + ++ + E++ L L+H N++ Sbjct: 1067 LGKGAYGTVYCGLTSQGQLIAVKQVALDTSNKLAAEKEYRKLQEEVDLLKALKHVNIVAY 1126 Query: 331 IGWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTLTWPQRYNILLGI 474 +G C + + E P GS+S ++ G + IL G+ Sbjct: 1127 LGTCLQENTVSIFMEFVPGGSISSIINRFGPLPEMVFCKYTKQILQGV 1174
>IGF1R_MOUSE (Q60751) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1373 Score = 44.7 bits (104), Expect = 1e-04 Identities = 27/102 (26%), Positives = 52/102 (50%), Gaps = 5/102 (4%) Frame = +1 Query: 118 ELVAATDNFSRDRKIGKGSFGDVYRGLLP-----MPDLREVAVKEMRQPTLKRNRKNYVH 282 E A + + +R++G+GSFG VY G+ P+ R VA+K + + R R +++ Sbjct: 992 EWEVAREKITMNRELGQGSFGMVYEGVAKGVVKDEPETR-VAIKTVNEAASMRERIEFLN 1050 Query: 283 EIETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHL 408 E + + ++++L+G G ++I EL G + +L Sbjct: 1051 EASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYL 1092
>PLK4_HUMAN (O00444) Serine/threonine-protein kinase PLK4 (EC 2.7.11.21)| (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine-protein kinase 18) Length = 970 Score = 44.7 bits (104), Expect = 1e-04 Identities = 27/93 (29%), Positives = 51/93 (54%), Gaps = 2/93 (2%) Frame = +1 Query: 136 DNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNR--KNYVHEIETLCQLR 309 ++F +GKGSF VYR L EVA+K + + + + + +E++ CQL+ Sbjct: 10 EDFKVGNLLGKGSFAGVYRAESIHTGL-EVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLK 68 Query: 310 HKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHL 408 H ++L+L + +D + L+ E+ NG ++ +L Sbjct: 69 HPSILELYNYFEDSNYVYLVLEMCHNGEMNRYL 101
>EPHA6_RAT (P54758) Ephrin type-A receptor 6 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2) Length = 1035 Score = 44.3 bits (103), Expect = 2e-04 Identities = 23/64 (35%), Positives = 37/64 (57%), Gaps = 2/64 (3%) Frame = +1 Query: 151 DRKIGKGSFGDVYRGLLPMPDLRE--VAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLL 324 +R IG G FG+V G L P RE VA+K ++ + R R++++ E + Q H N++ Sbjct: 633 ERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREASIMGQFDHPNII 692 Query: 325 QLIG 336 +L G Sbjct: 693 RLEG 696
>EPHA6_MOUSE (Q62413) Ephrin type-A receptor 6 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2) Length = 1035 Score = 44.3 bits (103), Expect = 2e-04 Identities = 23/64 (35%), Positives = 37/64 (57%), Gaps = 2/64 (3%) Frame = +1 Query: 151 DRKIGKGSFGDVYRGLLPMPDLRE--VAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLL 324 +R IG G FG+V G L P RE VA+K ++ + R R++++ E + Q H N++ Sbjct: 633 ERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREASIMGQFDHPNII 692 Query: 325 QLIG 336 +L G Sbjct: 693 RLEG 696
>EPHA6_HUMAN (Q9UF33) Ephrin type-A receptor 6 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2) Length = 1035 Score = 44.3 bits (103), Expect = 2e-04 Identities = 23/64 (35%), Positives = 37/64 (57%), Gaps = 2/64 (3%) Frame = +1 Query: 151 DRKIGKGSFGDVYRGLLPMPDLRE--VAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLL 324 +R IG G FG+V G L P RE VA+K ++ + R R++++ E + Q H N++ Sbjct: 633 ERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREASIMGQFDHPNII 692 Query: 325 QLIG 336 +L G Sbjct: 693 RLEG 696
>IGF1R_HUMAN (P08069) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 recepto Length = 1367 Score = 44.3 bits (103), Expect = 2e-04 Identities = 27/102 (26%), Positives = 51/102 (50%), Gaps = 5/102 (4%) Frame = +1 Query: 118 ELVAATDNFSRDRKIGKGSFGDVYRGLLP-----MPDLREVAVKEMRQPTLKRNRKNYVH 282 E A + + R++G+GSFG VY G+ P+ R VA+K + + R R +++ Sbjct: 991 EWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETR-VAIKTVNEAASMRERIEFLN 1049 Query: 283 EIETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHL 408 E + + ++++L+G G ++I EL G + +L Sbjct: 1050 EASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYL 1091
>IGF1R_BOVIN (Q05688) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] (F Length = 640 Score = 44.3 bits (103), Expect = 2e-04 Identities = 27/102 (26%), Positives = 51/102 (50%), Gaps = 5/102 (4%) Frame = +1 Query: 118 ELVAATDNFSRDRKIGKGSFGDVYRGLLP-----MPDLREVAVKEMRQPTLKRNRKNYVH 282 E A + + R++G+GSFG VY G+ P+ R VA+K + + R R +++ Sbjct: 264 EWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETR-VAIKTVNEAASMRERIEFLN 322 Query: 283 EIETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHL 408 E + + ++++L+G G ++I EL G + +L Sbjct: 323 EASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYL 364
>STK6_MOUSE (P97477) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Aurora-family kinase 1) (Aurora/IPL1-related kinase 1) (Ipl1- and aurora-related kinase 1) (Aurora-A) (Serine/threonine-protein kinase Ayk1) Length = 395 Score = 44.3 bits (103), Expect = 2e-04 Identities = 29/89 (32%), Positives = 46/89 (51%), Gaps = 2/89 (2%) Frame = +1 Query: 136 DNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYV--HEIETLCQLR 309 ++F R +GKG FG+VY +A+K + + L++ + E+E LR Sbjct: 122 EDFDIGRPLGKGKFGNVYLARERQSKFI-LALKVLFKTQLEKANVEHQLRREVEIQSHLR 180 Query: 310 HKNLLQLIGWCDDGGRLVLIYELEPNGSV 396 H N+L+L G+ D R+ LI E P G+V Sbjct: 181 HPNILRLYGYFHDATRVYLILEYAPLGTV 209
>EPHB3_BRARE (O13147) Ephrin type-B receptor 3 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor ZEK3) (EPH-like kinase 3) (Fragment) Length = 500 Score = 44.3 bits (103), Expect = 2e-04 Identities = 31/117 (26%), Positives = 55/117 (47%), Gaps = 13/117 (11%) Frame = +1 Query: 106 FSYSELVAATDNFSRD---------RKIGKGSFGDVYRGLLPMPDLRE--VAVKEMRQPT 252 F+Y + A F+R+ IG G FG+V RG L +E VA+K ++ Sbjct: 166 FTYEDPNEAVHEFAREIDISCVKIEEVIGAGEFGEVCRGRLKQAGRKETTVAIKTLKAGY 225 Query: 253 LKRNRKNYVHEIETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSD--HLHDG 417 + R++++ E + Q H N++ L G ++++ E NG++ L+DG Sbjct: 226 TEHQRRDFLSEASIMGQFDHPNVIHLEGVLTRSCPVLIVTEFMENGALDSFLRLNDG 282
>PLK4_MOUSE (Q64702) Serine/threonine-protein kinase PLK4 (EC 2.7.11.21)| (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine-protein kinase 18) Length = 925 Score = 44.3 bits (103), Expect = 2e-04 Identities = 27/93 (29%), Positives = 51/93 (54%), Gaps = 2/93 (2%) Frame = +1 Query: 136 DNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNR--KNYVHEIETLCQLR 309 ++F +GKGSF VYR L EVA+K + + + + + +E++ CQL+ Sbjct: 10 EDFKVGNLLGKGSFAGVYRAESIHTGL-EVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLK 68 Query: 310 HKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHL 408 H ++L+L + +D + L+ E+ NG ++ +L Sbjct: 69 HPSVLELYNYFEDNNYVYLVLEMCHNGEMNRYL 101
>IPL1_YARLI (Q6C3J2) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 371 Score = 44.3 bits (103), Expect = 2e-04 Identities = 41/130 (31%), Positives = 57/130 (43%), Gaps = 17/130 (13%) Frame = +1 Query: 58 RPTRCLDGNCLQVARKFSY-----SELVAAT-------DNFSRDRKIGKGSFGDVYRGLL 201 RPT QV+R+ SY S L T D+F + +GKG FG VY Sbjct: 59 RPTNLTKTPASQVSRRSSYTTDPPSPLTGITGFRNYSLDDFEIGKALGKGKFGKVYL--- 115 Query: 202 PMPDLRE---VAVKEMRQPTLKRNR--KNYVHEIETLCQLRHKNLLQLIGWCDDGGRLVL 366 + D + A+K M + L K + E+E LRH N+L+L G D R+ L Sbjct: 116 -VKDKKTGFVSALKCMEKKELVEGNVEKQFRREVEIQSNLRHTNVLRLFGHFHDKDRVYL 174 Query: 367 IYELEPNGSV 396 I E +G + Sbjct: 175 ILEYVVHGEL 184
>FGFR1_DROME (Q07407) Fibroblast growth factor receptor homolog 1 precursor (EC| 2.7.10.1) (Protein heartless) Length = 729 Score = 44.3 bits (103), Expect = 2e-04 Identities = 28/92 (30%), Positives = 50/92 (54%), Gaps = 1/92 (1%) Frame = +1 Query: 160 IGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQL-RHKNLLQLIG 336 +G+G+FG V ++ + VAVK +++ + + V E+E + + RH N++ L+G Sbjct: 422 LGEGAFGRV---VMAEVNNAIVAVKMVKEGHTDDDIASLVREMEVMKIIGRHINIINLLG 478 Query: 337 WCDDGGRLVLIYELEPNGSVSDHLHDGGASGR 432 C G L +I E P+G++ D L+ GR Sbjct: 479 CCSQNGPLYVIVEYAPHGNLKDFLYKNRPFGR 510
>CRK1_LEIME (Q06309) Cell division protein kinase 2 homolog CRK1 (EC 2.7.11.23)| Length = 301 Score = 43.9 bits (102), Expect = 2e-04 Identities = 25/82 (30%), Positives = 44/82 (53%), Gaps = 1/82 (1%) Frame = +1 Query: 133 TDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRK-NYVHEIETLCQLR 309 T + R KIG+G++G VY+ VA+K +R + + + EI L +LR Sbjct: 2 TSRYERQEKIGEGTYGVVYKA-RDTSTAATVALKRIRLDSEEEGVPCTAIREISLLKELR 60 Query: 310 HKNLLQLIGWCDDGGRLVLIYE 375 H+N+++L+ C RL +++E Sbjct: 61 HENIVKLLDVCHSEHRLTIVFE 82
>FGFR4_HUMAN (P22455) Fibroblast growth factor receptor 4 precursor (EC| 2.7.10.1) (FGFR-4) (CD334 antigen) Length = 802 Score = 43.9 bits (102), Expect = 2e-04 Identities = 34/101 (33%), Positives = 52/101 (51%), Gaps = 12/101 (11%) Frame = +1 Query: 142 FSRDRKI-----GKGSFGDVYR----GLLPM-PDLRE-VAVKEMRQPTLKRNRKNYVHEI 288 F RDR + G+G FG V R G+ P PD VAVK ++ ++ + V E+ Sbjct: 462 FPRDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEM 521 Query: 289 ETLCQL-RHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHL 408 E + + RHKN++ L+G C G L +I E G++ + L Sbjct: 522 EVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFL 562
>ERBB_ALV (P00534) Tyrosine-protein kinase transforming protein erbB (EC| 2.7.10.1) Length = 634 Score = 43.9 bits (102), Expect = 2e-04 Identities = 27/95 (28%), Positives = 53/95 (55%), Gaps = 4/95 (4%) Frame = +1 Query: 142 FSRDRKIGKGSFGDVYRGLLPMPDLREV----AVKEMRQPTLKRNRKNYVHEIETLCQLR 309 F + + +G G+FG VY+GL +P+ +V A+KE+R+ T + K + E + + Sbjct: 132 FKKVKVLGSGAFGTVYKGLW-IPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVD 190 Query: 310 HKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHD 414 + ++ +L+G C + LI +L P G + D++ + Sbjct: 191 NPHVCRLLGICLT-STVQLITQLMPYGCLLDYIRE 224
>PTK6_MOUSE (Q64434) Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related| intestinal kinase) Length = 451 Score = 43.9 bits (102), Expect = 2e-04 Identities = 29/93 (31%), Positives = 49/93 (52%) Frame = +1 Query: 136 DNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHK 315 + F+ +K+G G FG+V+ L VAVK + + L ++ + EI+ + +LRHK Sbjct: 189 EEFTLCKKLGAGYFGEVFEAL--WKGQVHVAVKVISRDNLL-HQHTFQAEIQAMKKLRHK 245 Query: 316 NLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHD 414 ++L L G + +I EL P G++ L D Sbjct: 246 HILSLYAVATAGDPVYIITELMPKGNLLQLLRD 278
>7LESS_DROME (P13368) Protein sevenless (EC 2.7.10.1)| Length = 2554 Score = 43.9 bits (102), Expect = 2e-04 Identities = 28/94 (29%), Positives = 47/94 (50%), Gaps = 3/94 (3%) Frame = +1 Query: 154 RKIGKGSFGDVYRGLLPMPDLRE---VAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLL 324 R +G G+FG+VY G L D E VA+K +R+ + + E + + +H+N++ Sbjct: 2213 RFLGSGAFGEVYEGQLKTEDSEEPQRVAIKSLRKGASEF--AELLQEAQLMSNFKHENIV 2270 Query: 325 QLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGAS 426 L+G C D + LI E G + +L A+ Sbjct: 2271 CLVGICFDTESISLIMEHMEAGDLLSYLRAARAT 2304
>FGFR4_MOUSE (Q03142) Fibroblast growth factor receptor 4 precursor (EC| 2.7.10.1) (FGFR-4) (Protein-tyrosine kinase receptor MPK-11) Length = 799 Score = 43.9 bits (102), Expect = 2e-04 Identities = 34/101 (33%), Positives = 52/101 (51%), Gaps = 12/101 (11%) Frame = +1 Query: 142 FSRDRKI-----GKGSFGDVYR----GLLPM-PDLRE-VAVKEMRQPTLKRNRKNYVHEI 288 F RDR + G+G FG V R G+ P PD VAVK ++ ++ + V E+ Sbjct: 459 FPRDRLVLGKPLGEGCFGQVVRAEAFGMDPSRPDQTSTVAVKMLKDNASDKDLADLVSEM 518 Query: 289 ETLCQL-RHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHL 408 E + + RHKN++ L+G C G L +I E G++ + L Sbjct: 519 EVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFL 559
>FGFR2_XENLA (Q03364) Fibroblast growth factor receptor 2 precursor (EC| 2.7.10.1) (FGFR-2) Length = 813 Score = 43.9 bits (102), Expect = 2e-04 Identities = 30/101 (29%), Positives = 50/101 (49%), Gaps = 12/101 (11%) Frame = +1 Query: 142 FSRDR-----KIGKGSFGDVYRGLLPMPDLRE------VAVKEMRQPTLKRNRKNYVHEI 288 FSRD+ +G+G FG V D VAVK ++ +++ + V E+ Sbjct: 466 FSRDKLTLGKPLGEGCFGQVVMAEALGIDKERPKESVTVAVKMLKDNATEKDLADLVSEM 525 Query: 289 ETLCQL-RHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHL 408 E + + +HKN++ L+G C GG L +I E G++ +L Sbjct: 526 EMMKMIGKHKNIINLLGACTQGGTLYVIVEYAAKGNLRQYL 566
>KIN31_CAEEL (P34265) Probable tyrosine-protein kinase kin-31 (EC 2.7.10.2)| Length = 437 Score = 43.5 bits (101), Expect = 3e-04 Identities = 26/94 (27%), Positives = 54/94 (57%), Gaps = 4/94 (4%) Frame = +1 Query: 139 NFSRDRKIGKGSFGDVYRGLLPMP---DLREVAVKEMRQPTLKRNR-KNYVHEIETLCQL 306 N ++K+G+G+FG+V G++ L +VAVK+++ + +++ K+++ E T+ L Sbjct: 129 NIVIEKKLGEGAFGEVSSGVMKFKRGGRLVKVAVKQVKTDGIGKDQIKDFLMEARTMRNL 188 Query: 307 RHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHL 408 H N+++ +G L L+ EL G++ +L Sbjct: 189 GHPNIVRFLGIAVLQEPLFLVMELATGGALDSYL 222
>STK6_RAT (P59241) Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Aurora-A)| (ratAurA) Length = 397 Score = 43.5 bits (101), Expect = 3e-04 Identities = 29/89 (32%), Positives = 46/89 (51%), Gaps = 2/89 (2%) Frame = +1 Query: 136 DNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYV--HEIETLCQLR 309 ++F R +GKG FG+VY +A+K + + L++ + E+E LR Sbjct: 124 EDFDIGRPLGKGKFGNVYLAREKQSKFI-LALKVLFKVQLEKAGVEHQLRREVEIQSHLR 182 Query: 310 HKNLLQLIGWCDDGGRLVLIYELEPNGSV 396 H N+L+L G+ D R+ LI E P G+V Sbjct: 183 HPNILRLYGYFHDATRVYLILEYAPLGTV 211
>EGFR_MOUSE (Q01279) Epidermal growth factor receptor precursor (EC 2.7.10.1)| Length = 1210 Score = 43.5 bits (101), Expect = 3e-04 Identities = 27/95 (28%), Positives = 53/95 (55%), Gaps = 4/95 (4%) Frame = +1 Query: 142 FSRDRKIGKGSFGDVYRGLLPMPDLREV----AVKEMRQPTLKRNRKNYVHEIETLCQLR 309 F + + +G G+FG VY+GL +P+ +V A+KE+R+ T + K + E + + Sbjct: 714 FKKIKVLGSGAFGTVYKGLW-IPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVD 772 Query: 310 HKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHD 414 + ++ +L+G C + LI +L P G + D++ + Sbjct: 773 NPHVCRLLGICLT-STVQLITQLMPYGCLLDYVRE 806
>CDC2C_DROME (P23573) Cell division control protein 2 cognate (EC 2.7.11.22) (EC| 2.7.11.23) Length = 314 Score = 43.5 bits (101), Expect = 3e-04 Identities = 27/81 (33%), Positives = 44/81 (54%), Gaps = 1/81 (1%) Frame = +1 Query: 136 DNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMR-QPTLKRNRKNYVHEIETLCQLRH 312 DNF R KIG+G++G VY+ ++VA+K++R + + + EI L L+H Sbjct: 6 DNFQRAEKIGEGTYGIVYKARSNSTG-QDVALKKIRLEGETEGVPSTAIREISLLKNLKH 64 Query: 313 KNLLQLIGWCDDGGRLVLIYE 375 N++QL G L +I+E Sbjct: 65 PNVVQLFDVVISGNNLYMIFE 85
>SRK1_SPOLA (P42686) Tyrosine-protein kinase isoform SRK1 (EC 2.7.10.2)| Length = 505 Score = 43.5 bits (101), Expect = 3e-04 Identities = 26/85 (30%), Positives = 46/85 (54%) Frame = +1 Query: 154 RKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLI 333 R++G G FG+V+ GL VAVK ++ T+ + + ++ E + +LRH L+QL Sbjct: 244 RRLGAGQFGEVWEGL--WNGTTSVAVKTLKPGTM--SVEEFLQEASIMKRLRHPKLIQLY 299 Query: 334 GWCDDGGRLVLIYELEPNGSVSDHL 408 C + ++ EL GS+ ++L Sbjct: 300 AVCTKEEPIYIVTELMKYGSLLEYL 324
>RIPK2_MOUSE (P58801) Receptor-interacting serine/threonine-protein kinase 2 (EC| 2.7.11.1) Length = 539 Score = 43.5 bits (101), Expect = 3e-04 Identities = 27/83 (32%), Positives = 43/83 (51%), Gaps = 2/83 (2%) Frame = +1 Query: 223 VAVKEMR--QPTLKRNRKNYVHEIETLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSV 396 VAVK + P L R + + E E L + R +L ++G C++ L ++ E PNGS+ Sbjct: 44 VAVKHLHIHTPLLDSERNDILREAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGSL 103 Query: 397 SDHLHDGGASGRTLTWPQRYNIL 465 ++ LH + WP R+ IL Sbjct: 104 NELLH-RKTEYPDIAWPLRFRIL 125
>RET_MOUSE (P35546) Proto-oncogene tyrosine-protein kinase receptor ret| precursor (EC 2.7.10.1) (C-ret) Length = 1115 Score = 43.5 bits (101), Expect = 3e-04 Identities = 28/101 (27%), Positives = 46/101 (45%), Gaps = 4/101 (3%) Frame = +1 Query: 139 NFSRDRKIGKGSFGDVYRG----LLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQL 306 N + +G+G FG V + L VAVK +++ + ++ + E L Q+ Sbjct: 724 NLVLGKTLGEGEFGKVVKATAFRLKGRAGYTTVAVKMLKENASQSELRDLLSEFNLLKQV 783 Query: 307 RHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGASG 429 H ++++L G C G L+LI E GS+ L D G Sbjct: 784 NHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRDSRKIG 824
>ERBB_AVIER (P00535) Tyrosine-protein kinase transforming protein erbB (EC| 2.7.10.1) Length = 604 Score = 43.5 bits (101), Expect = 3e-04 Identities = 26/95 (27%), Positives = 53/95 (55%), Gaps = 4/95 (4%) Frame = +1 Query: 142 FSRDRKIGKGSFGDVYRGLLPMPDLREV----AVKEMRQPTLKRNRKNYVHEIETLCQLR 309 F + + +G G+FG +Y+GL +P+ +V A+KE+R+ T + K + E + + Sbjct: 132 FKKVKVLGSGAFGTIYKGLW-IPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVD 190 Query: 310 HKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHD 414 + ++ +L+G C + LI +L P G + D++ + Sbjct: 191 NPHVCRLLGICLT-STVQLITQLMPYGCLLDYIRE 224
>ICL1_KLULA (Q6CWQ4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 361 Score = 43.5 bits (101), Expect = 3e-04 Identities = 34/106 (32%), Positives = 51/106 (48%), Gaps = 6/106 (5%) Frame = +1 Query: 139 NFSRDRKIGKGSFGDVY------RGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLC 300 +F + +GKG FG VY GL+ L+ + KE+ Q T++ K + E+E Sbjct: 99 DFEIGKILGKGKFGKVYCVKHRETGLICA--LKAMEKKEIVQYTIQ---KQFRREVEIQG 153 Query: 301 QLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTL 438 +HKNL QL G+ D R+ L+ E G + L + G TL Sbjct: 154 SFKHKNLTQLYGFFYDEKRVYLLMEYVYYGELYKFLKNNGPLNETL 199
>BTKL_DROME (P08630) Tyrosine-protein kinase Btk29A (EC 2.7.10.2) (Dsrc28C)| Length = 786 Score = 43.5 bits (101), Expect = 3e-04 Identities = 25/84 (29%), Positives = 47/84 (55%) Frame = +1 Query: 157 KIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLIG 336 ++G G FG V RG + AVK M++ T+ + +++ E + + +L+H NL+QL G Sbjct: 531 ELGSGQFGVVRRG--KWRGSIDTAVKMMKEGTMSED--DFIEEAKVMTKLQHPNLVQLYG 586 Query: 337 WCDDGGRLVLIYELEPNGSVSDHL 408 C + ++ E +GS+ ++L Sbjct: 587 VCSKHRPIYIVTEYMKHGSLLNYL 610
>ATG1_BOTCI (Q6H9I1) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) (Botryotinia fuckeliana putative kinase exons 1-3) Length = 952 Score = 43.5 bits (101), Expect = 3e-04 Identities = 30/88 (34%), Positives = 47/88 (53%), Gaps = 1/88 (1%) Frame = +1 Query: 139 NFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVH-EIETLCQLRHK 315 +F+ + +IGKGSF VYRG MP VA+K + L + K+ ++ EIE L L H Sbjct: 22 SFTINEQIGKGSFATVYRG-THMPSGNLVAIKSVNLSRLNKKLKDNLYVEIEILKSLYHP 80 Query: 316 NLLQLIGWCDDGGRLVLIYELEPNGSVS 399 +++ LI + + L+ E G +S Sbjct: 81 HIVALIDCRESASHIHLMMEYCELGDLS 108
>PGFRB_CANFA (Q6QNF3) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1103 Score = 43.1 bits (100), Expect = 4e-04 Identities = 28/97 (28%), Positives = 46/97 (47%), Gaps = 5/97 (5%) Frame = +1 Query: 136 DNFSRDRKIGKGSFGDVYR----GLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQ 303 D R +G G+FG V GL +VAVK ++ ++ + E++ + Sbjct: 598 DQLVLGRTLGSGAFGQVVEATAHGLSHSQATMKVAVKMLKSTARSSEKQALMSELKIMSH 657 Query: 304 LR-HKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLH 411 L H N++ L+G C GG + +I E G + D+LH Sbjct: 658 LGPHLNVVNLLGACTKGGPIYIITEYCRYGDLVDYLH 694
>SPK1_DUGTI (P42687) Tyrosine-protein kinase SPK-1 (EC 2.7.10.2)| Length = 497 Score = 43.1 bits (100), Expect = 4e-04 Identities = 28/101 (27%), Positives = 54/101 (53%), Gaps = 2/101 (1%) Frame = +1 Query: 112 YSELVAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIE 291 + ++ +N +IG+G FG V+R EVA K ++ K R+ +V E + Sbjct: 210 FQDIEINRENIEILNEIGRGFFGSVHRAKWGRS--YEVAAKMLQSS--KAEREKFVLEAK 265 Query: 292 TLCQLRHKNLLQLIGWCDD--GGRLVLIYELEPNGSVSDHL 408 + +LRH+ +++L+G C + +++I E NGS+ ++L Sbjct: 266 IMHKLRHRKIVELLGVCTEPQDMPMLIIVEYMKNGSLKEYL 306
>PGFRB_MOUSE (P05622) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1098 Score = 43.1 bits (100), Expect = 4e-04 Identities = 28/97 (28%), Positives = 46/97 (47%), Gaps = 5/97 (5%) Frame = +1 Query: 136 DNFSRDRKIGKGSFGDVYR----GLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQ 303 D R +G G+FG V GL +VAVK ++ ++ + E++ + Sbjct: 597 DQLVLGRTLGSGAFGQVVEATAHGLSHSQATMKVAVKMLKSTARSSEKQALMSELKIMSH 656 Query: 304 LR-HKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLH 411 L H N++ L+G C GG + +I E G + D+LH Sbjct: 657 LGPHLNVVNLLGACTKGGPIYIITEYCRYGDLVDYLH 693
>PR2_DROME (Q9I7F7) Tyrosine-protein kinase PR2 (EC 2.7.10.2)| Length = 1337 Score = 43.1 bits (100), Expect = 4e-04 Identities = 29/109 (26%), Positives = 56/109 (51%), Gaps = 1/109 (0%) Frame = +1 Query: 124 VAATDNFSRDRKIGKGSFGDVYRGLLPMPDLR-EVAVKEMRQPTLKRNRKNYVHEIETLC 300 + D+ S ++++G G FG V +G+ + R +VA+K + + ++ N ++ E + Sbjct: 127 IIPADSISVNKQLGTGEFGIVQQGVWSNGNERIQVAIKCLCRERMQSNPMEFLKEAAIMH 186 Query: 301 QLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTLTWP 447 + H+N+++L G L+L+ EL S+ + L D G LT P Sbjct: 187 SIEHENIVRLYGVVLATDSLMLVTELAHLRSLLECLKDSGLRVSFLTIP 235
>EGFR_HUMAN (P00533) Epidermal growth factor receptor precursor (EC 2.7.10.1)| (Receptor tyrosine-protein kinase ErbB-1) Length = 1210 Score = 43.1 bits (100), Expect = 4e-04 Identities = 27/95 (28%), Positives = 53/95 (55%), Gaps = 4/95 (4%) Frame = +1 Query: 142 FSRDRKIGKGSFGDVYRGLLPMPDLREV----AVKEMRQPTLKRNRKNYVHEIETLCQLR 309 F + + +G G+FG VY+GL +P+ +V A+KE+R+ T + K + E + + Sbjct: 712 FKKIKVLGSGAFGTVYKGLW-IPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVD 770 Query: 310 HKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHD 414 + ++ +L+G C + LI +L P G + D++ + Sbjct: 771 NPHVCRLLGICLT-STVQLITQLMPFGCLLDYVRE 804
>M3K6_HUMAN (O95382) Mitogen-activated protein kinase kinase kinase 6 (EC| 2.7.11.25) Length = 1011 Score = 43.1 bits (100), Expect = 4e-04 Identities = 28/83 (33%), Positives = 47/83 (56%) Frame = +1 Query: 160 IGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLIGW 339 +GKG++G VY G +R +A+KE+ + + ++ + EI +LRHKN+++ +G Sbjct: 377 LGKGTYGVVYAGRDRHTRVR-IAIKEIPERDSRFSQPLH-EEIALHRRLRHKNIVRYLGS 434 Query: 340 CDDGGRLVLIYELEPNGSVSDHL 408 GG L + E P GS+S L Sbjct: 435 ASQGGYLKIFMEEVPGGSLSSLL 457
>STK6_XENLA (Q91820) Serine/threonine-protein kinase Eg2 (EC 2.7.11.1) (pEg2)| (p46Eg265) Length = 407 Score = 43.1 bits (100), Expect = 4e-04 Identities = 29/93 (31%), Positives = 48/93 (51%), Gaps = 6/93 (6%) Frame = +1 Query: 136 DNFSRDRKIGKGSFGDVYRGLLPMPDLRE----VAVKEMRQPTLKRNRKNYV--HEIETL 297 ++F R +GKG FG+VY + RE +A+K + + L++ + E+E Sbjct: 138 EDFEIGRPLGKGKFGNVY-----LARERESKFILALKVLFKSQLEKAGVEHQLRREVEIQ 192 Query: 298 CQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSV 396 LRH N+L+L G+ D R+ LI + P G + Sbjct: 193 SHLRHPNILRLYGYFHDASRVYLILDYAPGGEL 225
>STK6L_XENLA (Q91819) Serine/threonine-protein kinase Eg2-like (EC 2.7.11.1)| (p46XlEg22) Length = 408 Score = 43.1 bits (100), Expect = 4e-04 Identities = 29/93 (31%), Positives = 48/93 (51%), Gaps = 6/93 (6%) Frame = +1 Query: 136 DNFSRDRKIGKGSFGDVYRGLLPMPDLRE----VAVKEMRQPTLKRNRKNYV--HEIETL 297 ++F R +GKG FG+VY + RE +A+K + + L++ + E+E Sbjct: 138 EDFEIGRPLGKGKFGNVY-----LARERESKFILALKVLFKSQLEKAGVEHQLRREVEIQ 192 Query: 298 CQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSV 396 LRH N+L+L G+ D R+ LI + P G + Sbjct: 193 SHLRHPNILRLYGYFHDASRVYLILDYAPGGEL 225
>PGFRB_HUMAN (P09619) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) (CD140b antigen) Length = 1106 Score = 43.1 bits (100), Expect = 4e-04 Identities = 28/97 (28%), Positives = 46/97 (47%), Gaps = 5/97 (5%) Frame = +1 Query: 136 DNFSRDRKIGKGSFGDVYR----GLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQ 303 D R +G G+FG V GL +VAVK ++ ++ + E++ + Sbjct: 598 DQLVLGRTLGSGAFGQVVEATAHGLSHSQATMKVAVKMLKSTARSSEKQALMSELKIMSH 657 Query: 304 LR-HKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLH 411 L H N++ L+G C GG + +I E G + D+LH Sbjct: 658 LGPHLNVVNLLGACTKGGPIYIITEYCRYGDLVDYLH 694
>PGFRB_RAT (Q05030) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1097 Score = 43.1 bits (100), Expect = 4e-04 Identities = 28/97 (28%), Positives = 46/97 (47%), Gaps = 5/97 (5%) Frame = +1 Query: 136 DNFSRDRKIGKGSFGDVYR----GLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQ 303 D R +G G+FG V GL +VAVK ++ ++ + E++ + Sbjct: 597 DQLVLGRTLGSGAFGQVVEATAHGLSHSQATMKVAVKMLKSTARSSEKQALMSELKIMSH 656 Query: 304 LR-HKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLH 411 L H N++ L+G C GG + +I E G + D+LH Sbjct: 657 LGPHLNVVNLLGACTKGGPIYIITEYCRYGDLVDYLH 693
>PHO85_KLULA (Q92241) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 304 Score = 42.7 bits (99), Expect = 5e-04 Identities = 23/88 (26%), Positives = 45/88 (51%) Frame = +1 Query: 124 VAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQ 303 + A F + K+G G++ VY+GL + VA+KE++ + + + EI + + Sbjct: 1 MVAPSQFKQLEKVGNGTYATVYKGLNKTTGV-YVALKEVKLDSEEGTPSTAIREISLMKE 59 Query: 304 LRHKNLLQLIGWCDDGGRLVLIYELEPN 387 L+H N+++L +L L++E N Sbjct: 60 LKHDNIVRLFDVIHTENKLTLVFEFMDN 87
>YRK_CHICK (Q02977) Proto-oncogene tyrosine-protein kinase Yrk (EC 2.7.10.2)| (p60-Yrk) (Yes-related kinase) Length = 535 Score = 42.7 bits (99), Expect = 5e-04 Identities = 31/99 (31%), Positives = 52/99 (52%) Frame = +1 Query: 154 RKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQLI 333 +K+G G FG+V+ G +VAVK ++ T+ + + ++ E + + +LRH L+QL Sbjct: 273 QKLGNGQFGEVWMG--TWNGTTKVAVKTLKPGTM--SPEAFLEEAQIMKRLRHDKLVQLY 328 Query: 334 GWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTLTWPQ 450 + + ++ E GS+ D L DG GR L PQ Sbjct: 329 AVVSE-EPIYIVTEFMSQGSLLDFLKDG--DGRYLKLPQ 364
>PHO85_YEAST (P17157) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 305 Score = 42.7 bits (99), Expect = 5e-04 Identities = 22/88 (25%), Positives = 48/88 (54%) Frame = +1 Query: 124 VAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQ 303 ++++ F + K+G G++ VY+GL + VA+KE++ + + + EI + + Sbjct: 1 MSSSSQFKQLEKLGNGTYATVYKGLNKTTGV-YVALKEVKLDSEEGTPSTAIREISLMKE 59 Query: 304 LRHKNLLQLIGWCDDGGRLVLIYELEPN 387 L+H+N+++L +L L++E N Sbjct: 60 LKHENIVRLYDVIHTENKLTLVFEFMDN 87
>ERBB_AVIEU (P11273) Tyrosine-protein kinase transforming protein erbB (EC| 2.7.10.1) Length = 540 Score = 42.7 bits (99), Expect = 5e-04 Identities = 27/95 (28%), Positives = 53/95 (55%), Gaps = 4/95 (4%) Frame = +1 Query: 142 FSRDRKIGKGSFGDVYRGLLPMPDLREV----AVKEMRQPTLKRNRKNYVHEIETLCQLR 309 F + + +G G+FG VY+GL +P+ +V A+KE+R+ T + K + E + + Sbjct: 132 FKKVKVLGFGAFGTVYKGLW-IPEGEKVTIPVAIKELREATSPKANKEILDEAYVMASVD 190 Query: 310 HKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHD 414 + ++ +L+G C + LI +L P G + D++ + Sbjct: 191 NPHVCRLLGICLT-STVQLITQLMPYGCLLDYIRE 224
>IPL1_ASHGO (Q755C4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 367 Score = 42.7 bits (99), Expect = 5e-04 Identities = 31/96 (32%), Positives = 47/96 (48%), Gaps = 6/96 (6%) Frame = +1 Query: 139 NFSRDRKIGKGSFGDVY------RGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLC 300 +F + +GKG FG VY G + L+ + K++ Q ++ K + E+E Sbjct: 108 DFEIGKVLGKGKFGRVYCVRHIESGFVCA--LKAMEKKDIIQYNIE---KQFRREVEIQS 162 Query: 301 QLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHL 408 LRH NL QL G+ D R+ L+ E NG + HL Sbjct: 163 SLRHPNLTQLYGYFHDEKRVYLLMEYLVNGELYKHL 198
>INSRR_MOUSE (Q9WTL4) Insulin receptor-related protein precursor (EC 2.7.10.1)| (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] Length = 1300 Score = 42.7 bits (99), Expect = 5e-04 Identities = 26/89 (29%), Positives = 45/89 (50%), Gaps = 4/89 (4%) Frame = +1 Query: 154 RKIGKGSFGDVYRGLLPMPDLRE----VAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNL 321 R++G+GSFG VY GL + E VA+K + + R R ++ E + + ++ Sbjct: 983 RELGQGSFGMVYEGLARGLEAGEESTPVALKTVNELASARERVEFLKEASVMKAFKCHHV 1042 Query: 322 LQLIGWCDDGGRLVLIYELEPNGSVSDHL 408 ++L+G G ++I EL G + HL Sbjct: 1043 VRLLGVVSQGQPTLVIMELMTRGDLKSHL 1071
>FGFR1_XENLA (P22182) Fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) Length = 812 Score = 42.4 bits (98), Expect = 6e-04 Identities = 26/100 (26%), Positives = 50/100 (50%), Gaps = 7/100 (7%) Frame = +1 Query: 130 ATDNFSRDRKIGKGSFGDVYRGLLPMPD------LREVAVKEMRQPTLKRNRKNYVHEIE 291 A D + +G+G FG V D + +VAVK ++ +++ + + E+E Sbjct: 468 ARDRLILGKPLGEGCFGQVVMAEAIGLDKEKPNKVTKVAVKMLKSDASEKDLSDLISEME 527 Query: 292 TLCQL-RHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHL 408 + + +HKN++ L+G C G L +I E G++ ++L Sbjct: 528 MMKMIGKHKNIINLLGACTQDGPLYVIVEYTSKGNLREYL 567
>INSR_AEDAE (Q93105) Insulin-like receptor precursor (EC 2.7.10.1) (MIR)| [Contains: Insulin-like receptor alpha chain; Insulin-like receptor beta chain] Length = 1390 Score = 42.4 bits (98), Expect = 6e-04 Identities = 25/90 (27%), Positives = 47/90 (52%), Gaps = 6/90 (6%) Frame = +1 Query: 157 KIGKGSFGDVYRGLLPMPDLR------EVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKN 318 ++G+GSFG VY+G+L LR A+K + + R + +++ E + Q + Sbjct: 1030 ELGQGSFGMVYKGILTQ--LRGEKCNQPCAIKTVNESATAREKDSFLLEASVMKQFNTHH 1087 Query: 319 LLQLIGWCDDGGRLVLIYELEPNGSVSDHL 408 +++L+G G ++I EL NG + +L Sbjct: 1088 VVRLLGVVSQGDPTLVIMELMANGDLKSYL 1117
>FGFR4_RAT (Q498D6) Fibroblast growth factor receptor 4 precursor (EC| 2.7.10.1) (FGFR-4) Length = 800 Score = 42.4 bits (98), Expect = 6e-04 Identities = 32/101 (31%), Positives = 50/101 (49%), Gaps = 12/101 (11%) Frame = +1 Query: 142 FSRDRKI-----GKGSFGDVYRG-LLPMPDLRE-----VAVKEMRQPTLKRNRKNYVHEI 288 F RDR + G+G FG V R L M R VAVK ++ ++ + + E+ Sbjct: 460 FPRDRLVLGKPLGEGCFGQVVRAEALGMDSSRPDQTSTVAVKMLKDNASDKDLADLISEM 519 Query: 289 ETLCQL-RHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHL 408 E + + RHKN++ L+G C G L +I E G++ + L Sbjct: 520 EMMKLIGRHKNIINLLGVCTQEGPLYVIVEYAAKGNLREFL 560
>CTR1_ARATH (Q05609) Serine/threonine-protein kinase CTR1 (EC 2.7.11.1)| Length = 821 Score = 42.4 bits (98), Expect = 6e-04 Identities = 30/90 (33%), Positives = 44/90 (48%), Gaps = 1/90 (1%) Frame = +1 Query: 157 KIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKN-YVHEIETLCQLRHKNLLQLI 333 KIG GSFG V+R D VAVK + + R N ++ E+ + +LRH N++ + Sbjct: 556 KIGAGSFGTVHRAEWHGSD---VAVKILMEQDFHAERVNEFLREVAIMKRLRHPNIVLFM 612 Query: 334 GWCDDGGRLVLIYELEPNGSVSDHLHDGGA 423 G L ++ E GS+ LH GA Sbjct: 613 GAVTQPPNLSIVTEYLSRGSLYRLLHKSGA 642
>FAK1_XENLA (Q91738) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| Length = 1068 Score = 42.4 bits (98), Expect = 6e-04 Identities = 23/69 (33%), Positives = 38/69 (55%), Gaps = 2/69 (2%) Frame = +1 Query: 136 DNFSRDRKIGKGSFGDVYRGLLPMPD--LREVAVKEMRQPTLKRNRKNYVHEIETLCQLR 309 D R IG+G FGDV++G+ P+ VA+K + T R+ ++ E T+ Q Sbjct: 433 DRIELGRCIGEGQFGDVHQGVYMSPENPAMAVAIKTCKNCTSDSVREKFLQEALTMRQFD 492 Query: 310 HKNLLQLIG 336 H ++++LIG Sbjct: 493 HPHIVKLIG 501
>INSR_XENLA (Q9PVZ4) Insulin receptor precursor (EC 2.7.10.1) (IR) (Xe-InsR)| (XTK-1b) [Contains: Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1362 Score = 42.4 bits (98), Expect = 6e-04 Identities = 27/96 (28%), Positives = 50/96 (52%), Gaps = 5/96 (5%) Frame = +1 Query: 136 DNFSRDRKIGKGSFGDVYRGLLP-----MPDLREVAVKEMRQPTLKRNRKNYVHEIETLC 300 D + R++G+GSFG VY G+ P++R VAVK + + R R +++E + Sbjct: 1010 DKINLLRELGQGSFGMVYEGIAKDIIKGEPEVR-VAVKTVNESASLRERIEFLNEASVMK 1068 Query: 301 QLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHL 408 ++++L+G G ++I EL +G + +L Sbjct: 1069 AFNCHHVVRLLGVVSKGQPTLVIMELMAHGDLKSYL 1104
>CC2H1_TRYBB (P38973) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| Length = 301 Score = 42.4 bits (98), Expect = 6e-04 Identities = 24/82 (29%), Positives = 46/82 (56%), Gaps = 4/82 (4%) Frame = +1 Query: 142 FSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNY----VHEIETLCQLR 309 + R +KIG+GS+G V+R D+ + +++ L++ + + EI L +LR Sbjct: 5 YERLQKIGEGSYGVVFRA----RDVTTGTIVAVKRIRLEKEEEGVPCTAIREISILKELR 60 Query: 310 HKNLLQLIGWCDDGGRLVLIYE 375 H+N+++L+ C RL L++E Sbjct: 61 HENIVRLLDVCHSEKRLTLVFE 82
>7LESS_DROVI (P20806) Protein sevenless (EC 2.7.10.1)| Length = 2594 Score = 42.4 bits (98), Expect = 6e-04 Identities = 27/88 (30%), Positives = 45/88 (51%), Gaps = 3/88 (3%) Frame = +1 Query: 154 RKIGKGSFGDVYRGLLPMPDLRE---VAVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLL 324 R +G G+FG+VY G L D + VA+K +R+ + + E + + +H+N++ Sbjct: 2228 RFLGSGAFGEVYEGQLQAEDEAQPQRVAIKSLRKGASEF--AELLQEAQLMSNFKHENIV 2285 Query: 325 QLIGWCDDGGRLVLIYELEPNGSVSDHL 408 LIG C D + LI E G + +L Sbjct: 2286 CLIGICCDTDSISLIMEHMEAGDLLSYL 2313
>M3K2_ARATH (Q9FZ36) Mitogen-activated protein kinase kinase kinase 2 (EC| 2.7.11.25) (Arabidospsis NPK1-related protein kinase 2) Length = 651 Score = 42.0 bits (97), Expect = 8e-04 Identities = 33/113 (29%), Positives = 54/113 (47%), Gaps = 8/113 (7%) Frame = +1 Query: 160 IGKGSFGDVYRGL-LPMPDLREVAVKEMR-QPTLKRNRKNYVH------EIETLCQLRHK 315 IG+G+FG VY G+ L +L +AVK++ K H E++ L L H Sbjct: 74 IGRGAFGTVYMGMNLDSGEL--LAVKQVLITSNCASKEKTQAHIQELEEEVKLLKNLSHP 131 Query: 316 NLLQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTLTWPQRYNILLGI 474 N+++ +G + L ++ E P GS+S L GA ++ +LLG+ Sbjct: 132 NIVRYLGTVREDETLNILLEFVPGGSISSLLEKFGAFPESVVRTYTNQLLLGL 184
>CAD96_DROME (Q9VBW3) Tyrosine kinase receptor Cad96Ca precursor (EC 2.7.10.1)| (Cadherin 96Ca) (Tyrosine kinase receptor HD-14) Length = 773 Score = 42.0 bits (97), Expect = 8e-04 Identities = 26/93 (27%), Positives = 47/93 (50%), Gaps = 5/93 (5%) Frame = +1 Query: 160 IGKGSFGDVYR----GLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLR-HKNLL 324 +G+G+FG V+R + + VAVK +++ + +RK+ + E+E + L H N++ Sbjct: 476 LGEGAFGQVWRCEATNINGNEGITTVAVKTLKESATEVDRKDLLSELEVMKSLEPHINVV 535 Query: 325 QLIGWCDDGGRLVLIYELEPNGSVSDHLHDGGA 423 L+G C D +I E G + +L A Sbjct: 536 HLLGCCTDKDPTFVILEYVNRGKLQTYLRSSRA 568
>CDC7_SCHPO (P41892) Cell division control protein 7 (EC 2.7.11.1)| Length = 1062 Score = 42.0 bits (97), Expect = 8e-04 Identities = 33/106 (31%), Positives = 51/106 (48%), Gaps = 1/106 (0%) Frame = +1 Query: 160 IGKGSFGDVYRGLLPMPDLREVAVKEMR-QPTLKRNRKNYVHEIETLCQLRHKNLLQLIG 336 +GKG+FG VYRG L + + VAVK+++ LK + EI+ L L H N+++ G Sbjct: 15 LGKGAFGAVYRG-LNIKNGETVAVKKVKLSKMLKSDLSVIKMEIDLLKNLDHPNIVKYRG 73 Query: 337 WCDDGGRLVLIYELEPNGSVSDHLHDGGASGRTLTWPQRYNILLGI 474 L +I E NGS+ + G L + +L G+ Sbjct: 74 SYQTNDSLCIILEYCENGSLRSICKNFGKIPENLVALYTFQVLQGL 119
>BUR1_CANGA (Q6FQ83) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 667 Score = 42.0 bits (97), Expect = 8e-04 Identities = 28/95 (29%), Positives = 51/95 (53%), Gaps = 6/95 (6%) Frame = +1 Query: 139 NFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYV------HEIETLC 300 N+ + K+G+G+FG+VY+G L + R+VA+K + N++N + EI L Sbjct: 59 NYKEEEKLGQGTFGEVYKG-LHLQTQRKVAMKR-----IIVNQENDLFPITAQREITILK 112 Query: 301 QLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDH 405 +L HKN+++L L ++Y+ P + D+ Sbjct: 113 RLNHKNIIKL---------LEMVYDFPPESNNKDY 138
>ZYG1_CAEBR (Q621J7) Probable serine/threonine-protein kinase zyg-1 (EC| 2.7.11.1) (Zygote defective protein 1) Length = 709 Score = 42.0 bits (97), Expect = 8e-04 Identities = 28/94 (29%), Positives = 48/94 (51%) Frame = +1 Query: 139 NFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMRQPTLKRNRKNYVHEIETLCQLRHKN 318 +F ++IG+G FG VY + +VA+K++ + K EI+T+ LRH+N Sbjct: 12 SFQNLQQIGQGGFGVVYSA--QRENGEKVAIKKIGNAASQTRIK---EEIKTMKLLRHRN 66 Query: 319 LLQLIGWCDDGGRLVLIYELEPNGSVSDHLHDGG 420 ++Q + G L+ EL GS+ D++ G Sbjct: 67 IVQFYETFFENGETYLVMELCEGGSLMDYVKQKG 100
>DDR1_HUMAN (Q08345) Epithelial discoidin domain-containing receptor 1| precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) Length = 913 Score = 42.0 bits (97), Expect = 8e-04 Identities = 26/99 (26%), Positives = 51/99 (51%), Gaps = 15/99 (15%) Frame = +1 Query: 157 KIGKGSFGDVYRGLLPMP----------DLRE-----VAVKEMRQPTLKRNRKNYVHEIE 291 K+G+G FG+V+ + P ++R+ VAVK +R K R +++ E++ Sbjct: 615 KLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVK 674 Query: 292 TLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHL 408 + +L+ N+++L+G C L +I + NG ++ L Sbjct: 675 IMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFL 713
>EGFR_DROME (P04412) Epidermal growth factor receptor precursor (EC 2.7.10.1)| (Egfr) (Gurken receptor) (Protein torpedo) (Drosophila relative of ERBB) Length = 1426 Score = 42.0 bits (97), Expect = 8e-04 Identities = 26/89 (29%), Positives = 50/89 (56%), Gaps = 4/89 (4%) Frame = +1 Query: 160 IGKGSFGDVYRGLLPMPDLREV----AVKEMRQPTLKRNRKNYVHEIETLCQLRHKNLLQ 327 +G G+FG VY+G+ +P+ V A+KE+ + T + + ++ E + H NLL+ Sbjct: 944 LGMGAFGRVYKGVW-VPEGENVKIPVAIKELLKSTGAESSEEFLREAYIMASEEHVNLLK 1002 Query: 328 LIGWCDDGGRLVLIYELEPNGSVSDHLHD 414 L+ C +++LI +L P G + D++ + Sbjct: 1003 LLAVC-MSSQMMLITQLMPLGCLLDYVRN 1030
>FGFR2_MOUSE (P21803) Fibroblast growth factor receptor 2 precursor (EC| 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor) Length = 821 Score = 42.0 bits (97), Expect = 8e-04 Identities = 26/98 (26%), Positives = 49/98 (50%), Gaps = 7/98 (7%) Frame = +1 Query: 136 DNFSRDRKIGKGSFGDVYRGLLPMPDLRE------VAVKEMRQPTLKRNRKNYVHEIETL 297 D + + +G+G FG V D + VAVK ++ +++ + V E+E + Sbjct: 479 DKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMM 538 Query: 298 CQL-RHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHL 408 + +HKN++ L+G C G L +I E G++ ++L Sbjct: 539 KMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYL 576
>FGFR2_HUMAN (P21802) Fibroblast growth factor receptor 2 precursor (EC| 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor 2) (CD332 antigen) Length = 821 Score = 42.0 bits (97), Expect = 8e-04 Identities = 26/98 (26%), Positives = 49/98 (50%), Gaps = 7/98 (7%) Frame = +1 Query: 136 DNFSRDRKIGKGSFGDVYRGLLPMPDLRE------VAVKEMRQPTLKRNRKNYVHEIETL 297 D + + +G+G FG V D + VAVK ++ +++ + V E+E + Sbjct: 479 DKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMM 538 Query: 298 CQL-RHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHL 408 + +HKN++ L+G C G L +I E G++ ++L Sbjct: 539 KMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYL 576
>DDR1_PANTR (Q7YR43) Epithelial discoidin domain-containing receptor 1| precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (CD167a antigen) Length = 909 Score = 42.0 bits (97), Expect = 8e-04 Identities = 26/99 (26%), Positives = 51/99 (51%), Gaps = 15/99 (15%) Frame = +1 Query: 157 KIGKGSFGDVYRGLLPMP----------DLRE-----VAVKEMRQPTLKRNRKNYVHEIE 291 K+G+G FG+V+ + P ++R+ VAVK +R K R +++ E++ Sbjct: 611 KLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVK 670 Query: 292 TLCQLRHKNLLQLIGWCDDGGRLVLIYELEPNGSVSDHL 408 + +L+ N+++L+G C L +I + NG ++ L Sbjct: 671 IMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFL 709
>NEK6_RAT (P59895) Serine/threonine-protein kinase Nek6 (EC 2.7.11.1)| (NimA-related protein kinase 6) Length = 313 Score = 41.6 bits (96), Expect = 0.001 Identities = 26/89 (29%), Positives = 50/89 (56%), Gaps = 2/89 (2%) Frame = +1 Query: 139 NFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMR--QPTLKRNRKNYVHEIETLCQLRH 312 +F ++KIG+G F +VY+ + D + VA+K+++ + + R++ V EI L QL H Sbjct: 44 DFQIEKKIGRGQFSEVYKATC-LLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNH 102 Query: 313 KNLLQLIGWCDDGGRLVLIYELEPNGSVS 399 N+++ + + L ++ EL G +S Sbjct: 103 PNIIKYLDSFIEDNELNIVLELADAGDLS 131
>NEK6_MOUSE (Q9ES70) Serine/threonine-protein kinase Nek6 (EC 2.7.11.1)| (NimA-related protein kinase 6) Length = 313 Score = 41.6 bits (96), Expect = 0.001 Identities = 26/89 (29%), Positives = 50/89 (56%), Gaps = 2/89 (2%) Frame = +1 Query: 139 NFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMR--QPTLKRNRKNYVHEIETLCQLRH 312 +F ++KIG+G F +VY+ + D + VA+K+++ + + R++ V EI L QL H Sbjct: 44 DFQIEKKIGRGQFSEVYKATC-LLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNH 102 Query: 313 KNLLQLIGWCDDGGRLVLIYELEPNGSVS 399 N+++ + + L ++ EL G +S Sbjct: 103 PNIIKYLDSFIEDNELNIVLELADAGDLS 131
>NEK6_HUMAN (Q9HC98) Serine/threonine-protein kinase Nek6 (EC 2.7.11.1)| (NimA-related protein kinase 6) (Protein kinase SID6-1512) Length = 313 Score = 41.6 bits (96), Expect = 0.001 Identities = 26/89 (29%), Positives = 50/89 (56%), Gaps = 2/89 (2%) Frame = +1 Query: 139 NFSRDRKIGKGSFGDVYRGLLPMPDLREVAVKEMR--QPTLKRNRKNYVHEIETLCQLRH 312 +F ++KIG+G F +VY+ + D + VA+K+++ + + R++ V EI L QL H Sbjct: 44 DFQIEKKIGRGQFSEVYKATC-LLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNH 102 Query: 313 KNLLQLIGWCDDGGRLVLIYELEPNGSVS 399 N+++ + + L ++ EL G +S Sbjct: 103 PNIIKYLDSFIEDNELNIVLELADAGDLS 131
>M3K2_HUMAN (Q9Y2U5) Mitogen-activated protein kinase kinase kinase 2 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2) Length = 619 Score = 41.6 bits (96), Expect = 0.001 Identities = 41/147 (27%), Positives = 62/147 (42%), Gaps = 6/147 (4%) Frame = +1 Query: 52 IKRPTRCLDGNCLQVARKFSYSELVAATDNFSRDRKIGKGSFGDVYRGLLPMPDLREVAV 231 I+R +D L V S A N+ + +G+G+FG VY + RE+AV Sbjct: 326 IRRRGSDIDNPTLTVMDISPPSRSPRAPTNWRLGKLLGQGAFGRVYL-CYDVDTGRELAV 384 Query: 232 KEMR----QPTLKRNRKNYVHEIETLCQLRHKNLLQLIGWCDDGGR--LVLIYELEPNGS 393 K+++ P + EI+ L L H+ ++Q G D L + E P GS Sbjct: 385 KQVQFDPDSPETSKEVNALECEIQLLKNLLHERIVQYYGCLRDPQEKTLSIFMEYMPGGS 444 Query: 394 VSDHLHDGGASGRTLTWPQRYNILLGI 474 + D L GA +T IL G+ Sbjct: 445 IKDQLKAYGALTENVTRKYTRQILEGV 471 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 64,437,863 Number of Sequences: 219361 Number of extensions: 1282838 Number of successful extensions: 5395 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 4947 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5094 length of database: 80,573,946 effective HSP length: 103 effective length of database: 57,979,763 effective search space used: 3130907202 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
