ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | baal14h12 |
|---|---|
| Clone Library Name | barley_pub |
>KC1D_ARATH (P42158) Casein kinase I isoform delta-like (EC 2.7.11.1)| (CKI-delta) Length = 450 Score = 359 bits (922), Expect(2) = 1e-98 Identities = 171/185 (92%), Positives = 182/185 (98%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLV 238 EIYLGTNI TNEE+ IKLENVKTKHPQLLYESK+YRILQGGTG+PNV+WFGVEGDYNVLV Sbjct: 22 EIYLGTNIHTNEELAIKLENVKTKHPQLLYESKLYRILQGGTGVPNVKWFGVEGDYNVLV 81 Query: 239 MDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRR 418 MDLLGPSLEDLFNFCSRKLSLK+VLMLADQMINRVEF HSKSFLHRD+KPDNFLMGLGRR Sbjct: 82 MDLLGPSLEDLFNFCSRKLSLKSVLMLADQMINRVEFFHSKSFLHRDLKPDNFLMGLGRR 141 Query: 419 ANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGY 598 ANQVY+IDFGLAKKYRD++THQHIPYRENKNLTGTARYAS+NTHLGIEQSRRDDLESLGY Sbjct: 142 ANQVYIIDFGLAKKYRDSTTHQHIPYRENKNLTGTARYASMNTHLGIEQSRRDDLESLGY 201 Query: 599 VLMYF 613 +LMYF Sbjct: 202 ILMYF 206 Score = 20.8 bits (42), Expect(2) = 1e-98 Identities = 8/8 (100%), Positives = 8/8 (100%) Frame = +1 Query: 13 NKFRLGRK 36 NKFRLGRK Sbjct: 7 NKFRLGRK 14
>KC1D_RAT (Q06486) Casein kinase I isoform delta (EC 2.7.11.1) (CKI-delta)| Length = 415 Score = 320 bits (820), Expect = 2e-87 Identities = 149/185 (80%), Positives = 169/185 (91%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLV 238 +IYLGT+I EEV IKLE VKTKHPQL ESKIY+++QGG GIP +RW G EGDYNV+V Sbjct: 22 DIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMV 81 Query: 239 MDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRR 418 M+LLGPSLEDLFNFCSRK SLKTVL+LADQMI+R+E++HSK+F+HRD+KPDNFLMGLG++ Sbjct: 82 MELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKK 141 Query: 419 ANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGY 598 N VY+IDFGLAKKYRD THQHIPYRENKNLTGTARYAS+NTHLGIEQSRRDDLESLGY Sbjct: 142 GNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGY 201 Query: 599 VLMYF 613 VLMYF Sbjct: 202 VLMYF 206
>KC1D_MOUSE (Q9DC28) Casein kinase I isoform delta (EC 2.7.11.1) (CKI-delta)| (CKId) Length = 415 Score = 320 bits (820), Expect = 2e-87 Identities = 149/185 (80%), Positives = 169/185 (91%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLV 238 +IYLGT+I EEV IKLE VKTKHPQL ESKIY+++QGG GIP +RW G EGDYNV+V Sbjct: 22 DIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMV 81 Query: 239 MDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRR 418 M+LLGPSLEDLFNFCSRK SLKTVL+LADQMI+R+E++HSK+F+HRD+KPDNFLMGLG++ Sbjct: 82 MELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKK 141 Query: 419 ANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGY 598 N VY+IDFGLAKKYRD THQHIPYRENKNLTGTARYAS+NTHLGIEQSRRDDLESLGY Sbjct: 142 GNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGY 201 Query: 599 VLMYF 613 VLMYF Sbjct: 202 VLMYF 206
>KC1D_HUMAN (P48730) Casein kinase I isoform delta (EC 2.7.11.1) (CKI-delta)| (CKId) Length = 415 Score = 320 bits (820), Expect = 2e-87 Identities = 149/185 (80%), Positives = 169/185 (91%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLV 238 +IYLGT+I EEV IKLE VKTKHPQL ESKIY+++QGG GIP +RW G EGDYNV+V Sbjct: 22 DIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMV 81 Query: 239 MDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRR 418 M+LLGPSLEDLFNFCSRK SLKTVL+LADQMI+R+E++HSK+F+HRD+KPDNFLMGLG++ Sbjct: 82 MELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKK 141 Query: 419 ANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGY 598 N VY+IDFGLAKKYRD THQHIPYRENKNLTGTARYAS+NTHLGIEQSRRDDLESLGY Sbjct: 142 GNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGY 201 Query: 599 VLMYF 613 VLMYF Sbjct: 202 VLMYF 206
>KC1E_MOUSE (Q9JMK2) Casein kinase I isoform epsilon (EC 2.7.11.1)| (CKI-epsilon) (CKIe) Length = 416 Score = 318 bits (815), Expect = 8e-87 Identities = 147/185 (79%), Positives = 169/185 (91%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLV 238 +IYLG NI + EEV IKLE VKTKHPQL ESK Y+++QGG GIP+++W G EGDYNV+V Sbjct: 22 DIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQGGVGIPSIKWCGAEGDYNVMV 81 Query: 239 MDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRR 418 M+LLGPSLEDLFNFCSRK SLKTVL+LADQMI+R+E++HSK+F+HRD+KPDNFLMGLG++ Sbjct: 82 MELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKK 141 Query: 419 ANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGY 598 N VY+IDFGLAKKYRD THQHIPYRENKNLTGTARYAS+NTHLGIEQSRRDDLESLGY Sbjct: 142 GNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGY 201 Query: 599 VLMYF 613 VLMYF Sbjct: 202 VLMYF 206
>KC1E_HUMAN (P49674) Casein kinase I isoform epsilon (EC 2.7.11.1)| (CKI-epsilon) (CKIe) Length = 416 Score = 318 bits (815), Expect = 8e-87 Identities = 147/185 (79%), Positives = 169/185 (91%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLV 238 +IYLG NI + EEV IKLE VKTKHPQL ESK Y+++QGG GIP+++W G EGDYNV+V Sbjct: 22 DIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQGGVGIPSIKWCGAEGDYNVMV 81 Query: 239 MDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRR 418 M+LLGPSLEDLFNFCSRK SLKTVL+LADQMI+R+E++HSK+F+HRD+KPDNFLMGLG++ Sbjct: 82 MELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKK 141 Query: 419 ANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGY 598 N VY+IDFGLAKKYRD THQHIPYRENKNLTGTARYAS+NTHLGIEQSRRDDLESLGY Sbjct: 142 GNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGY 201 Query: 599 VLMYF 613 VLMYF Sbjct: 202 VLMYF 206
>HHP1_SCHPO (P40235) Casein kinase I homolog hhp1 (EC 2.7.11.1)| Length = 365 Score = 315 bits (808), Expect = 5e-86 Identities = 148/185 (80%), Positives = 167/185 (90%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLV 238 +IYLGTN+ + EEV IKLE+ + KHPQL YE ++YRIL GG GIP VRWFGVE DYN +V Sbjct: 24 DIYLGTNVVSGEEVAIKLESTRAKHPQLEYEYRVYRILSGGVGIPFVRWFGVECDYNAMV 83 Query: 239 MDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRR 418 MDLLGPSLEDLFNFC+RK SLKTVL+LADQ+I+R+EF+HSKSFLHRDIKPDNFLMG+G+R Sbjct: 84 MDLLGPSLEDLFNFCNRKFSLKTVLLLADQLISRIEFIHSKSFLHRDIKPDNFLMGIGKR 143 Query: 419 ANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGY 598 NQV +IDFGLAKKYRD TH HIPYRENKNLTGTARYAS+NTHLGIEQSRRDDLESLGY Sbjct: 144 GNQVNIIDFGLAKKYRDHKTHLHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGY 203 Query: 599 VLMYF 613 VL+YF Sbjct: 204 VLVYF 208
>KC1_TOXGO (Q6QNM1) Casein kinase I (EC 2.7.11.1)| Length = 324 Score = 311 bits (797), Expect = 1e-84 Identities = 143/185 (77%), Positives = 169/185 (91%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLV 238 +IY+G NI T +EV IKLE++K+KHPQLLYESK+Y++L GG GIP V W+G+EGDYNV+V Sbjct: 22 DIYIGANILTGDEVAIKLESIKSKHPQLLYESKLYKLLAGGIGIPMVHWYGIEGDYNVMV 81 Query: 239 MDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRR 418 +DLLGPSLEDLF+ C+RKLSLKTVLMLADQM+NR+EFVHSK+F+HRDIKPDNFL+G G++ Sbjct: 82 IDLLGPSLEDLFSICNRKLSLKTVLMLADQMLNRIEFVHSKNFIHRDIKPDNFLIGRGKK 141 Query: 419 ANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGY 598 + VY+IDFGLAKKYRD T QHIPYRE KNLTGTARYAS+NTHLGIEQSRRDDLE+LGY Sbjct: 142 MSVVYIIDFGLAKKYRDPKTQQHIPYREGKNLTGTARYASINTHLGIEQSRRDDLEALGY 201 Query: 599 VLMYF 613 VLMYF Sbjct: 202 VLMYF 206
>KC1A_SHEEP (P67829) Casein kinase I isoform alpha (EC 2.7.11.1) (CKI-alpha)| (CK1) Length = 325 Score = 308 bits (789), Expect = 8e-84 Identities = 141/185 (76%), Positives = 167/185 (90%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLV 238 +IYL NI EEV +KLE+ K +HPQLLYESK+Y+ILQGG GIP++RW+G E DYNVLV Sbjct: 30 DIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWYGQEKDYNVLV 89 Query: 239 MDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRR 418 MDLLGPSLEDLFNFCSR+ ++KTVLMLADQMI+R+E+VH+K+F+HRDIKPDNFLMG+GR Sbjct: 90 MDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRH 149 Query: 419 ANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGY 598 N++++IDFGLAKKYRD T QHIPYRE+KNLTGTARYAS+N HLGIEQSRRDD+ESLGY Sbjct: 150 CNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGY 209 Query: 599 VLMYF 613 VLMYF Sbjct: 210 VLMYF 214
>KC1A_RABIT (P67828) Casein kinase I isoform alpha (EC 2.7.11.1) (CKI-alpha)| (CK1) Length = 325 Score = 308 bits (789), Expect = 8e-84 Identities = 141/185 (76%), Positives = 167/185 (90%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLV 238 +IYL NI EEV +KLE+ K +HPQLLYESK+Y+ILQGG GIP++RW+G E DYNVLV Sbjct: 30 DIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWYGQEKDYNVLV 89 Query: 239 MDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRR 418 MDLLGPSLEDLFNFCSR+ ++KTVLMLADQMI+R+E+VH+K+F+HRDIKPDNFLMG+GR Sbjct: 90 MDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRH 149 Query: 419 ANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGY 598 N++++IDFGLAKKYRD T QHIPYRE+KNLTGTARYAS+N HLGIEQSRRDD+ESLGY Sbjct: 150 CNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGY 209 Query: 599 VLMYF 613 VLMYF Sbjct: 210 VLMYF 214
>KC1A_BOVIN (P67827) Casein kinase I isoform alpha (EC 2.7.11.1) (CKI-alpha)| (CK1) Length = 325 Score = 308 bits (789), Expect = 8e-84 Identities = 141/185 (76%), Positives = 167/185 (90%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLV 238 +IYL NI EEV +KLE+ K +HPQLLYESK+Y+ILQGG GIP++RW+G E DYNVLV Sbjct: 30 DIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWYGQEKDYNVLV 89 Query: 239 MDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRR 418 MDLLGPSLEDLFNFCSR+ ++KTVLMLADQMI+R+E+VH+K+F+HRDIKPDNFLMG+GR Sbjct: 90 MDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRH 149 Query: 419 ANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGY 598 N++++IDFGLAKKYRD T QHIPYRE+KNLTGTARYAS+N HLGIEQSRRDD+ESLGY Sbjct: 150 CNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGY 209 Query: 599 VLMYF 613 VLMYF Sbjct: 210 VLMYF 214
>KC1A_XENLA (P67963) Casein kinase I isoform alpha (EC 2.7.11.1) (CKI-alpha)| (CK1) Length = 337 Score = 308 bits (789), Expect = 8e-84 Identities = 141/185 (76%), Positives = 167/185 (90%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLV 238 +IYL NI EEV +KLE+ K +HPQLLYESK+Y+ILQGG GIP++RW+G E DYNVLV Sbjct: 30 DIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWYGQEKDYNVLV 89 Query: 239 MDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRR 418 MDLLGPSLEDLFNFCSR+ ++KTVLMLADQMI+R+E+VH+K+F+HRDIKPDNFLMG+GR Sbjct: 90 MDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRH 149 Query: 419 ANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGY 598 N++++IDFGLAKKYRD T QHIPYRE+KNLTGTARYAS+N HLGIEQSRRDD+ESLGY Sbjct: 150 CNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGY 209 Query: 599 VLMYF 613 VLMYF Sbjct: 210 VLMYF 214
>KC1A_MOUSE (Q8BK63) Casein kinase I isoform alpha (EC 2.7.11.1) (CKI-alpha)| (CK1) Length = 337 Score = 308 bits (789), Expect = 8e-84 Identities = 141/185 (76%), Positives = 167/185 (90%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLV 238 +IYL NI EEV +KLE+ K +HPQLLYESK+Y+ILQGG GIP++RW+G E DYNVLV Sbjct: 30 DIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWYGQEKDYNVLV 89 Query: 239 MDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRR 418 MDLLGPSLEDLFNFCSR+ ++KTVLMLADQMI+R+E+VH+K+F+HRDIKPDNFLMG+GR Sbjct: 90 MDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRH 149 Query: 419 ANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGY 598 N++++IDFGLAKKYRD T QHIPYRE+KNLTGTARYAS+N HLGIEQSRRDD+ESLGY Sbjct: 150 CNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGY 209 Query: 599 VLMYF 613 VLMYF Sbjct: 210 VLMYF 214
>KC1A_HUMAN (P48729) Casein kinase I isoform alpha (EC 2.7.11.1) (CKI-alpha)| (CK1) Length = 337 Score = 308 bits (789), Expect = 8e-84 Identities = 141/185 (76%), Positives = 167/185 (90%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLV 238 +IYL NI EEV +KLE+ K +HPQLLYESK+Y+ILQGG GIP++RW+G E DYNVLV Sbjct: 30 DIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWYGQEKDYNVLV 89 Query: 239 MDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRR 418 MDLLGPSLEDLFNFCSR+ ++KTVLMLADQMI+R+E+VH+K+F+HRDIKPDNFLMG+GR Sbjct: 90 MDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRH 149 Query: 419 ANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGY 598 N++++IDFGLAKKYRD T QHIPYRE+KNLTGTARYAS+N HLGIEQSRRDD+ESLGY Sbjct: 150 CNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGY 209 Query: 599 VLMYF 613 VLMYF Sbjct: 210 VLMYF 214
>KC1A_CHICK (P67962) Casein kinase I isoform alpha (EC 2.7.11.1) (CKI-alpha)| (CK1) Length = 337 Score = 308 bits (789), Expect = 8e-84 Identities = 141/185 (76%), Positives = 167/185 (90%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLV 238 +IYL NI EEV +KLE+ K +HPQLLYESK+Y+ILQGG GIP++RW+G E DYNVLV Sbjct: 30 DIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWYGQEKDYNVLV 89 Query: 239 MDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRR 418 MDLLGPSLEDLFNFCSR+ ++KTVLMLADQMI+R+E+VH+K+F+HRDIKPDNFLMG+GR Sbjct: 90 MDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRH 149 Query: 419 ANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGY 598 N++++IDFGLAKKYRD T QHIPYRE+KNLTGTARYAS+N HLGIEQSRRDD+ESLGY Sbjct: 150 CNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGY 209 Query: 599 VLMYF 613 VLMYF Sbjct: 210 VLMYF 214
>KC1A_RAT (P97633) Casein kinase I isoform alpha (EC 2.7.11.1) (CKI-alpha)| (CK1) Length = 325 Score = 305 bits (782), Expect = 5e-83 Identities = 140/185 (75%), Positives = 166/185 (89%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLV 238 +IYL NI EEV +KLE+ K +HPQLLYESK+Y+ILQGG GIP++RW+G DYNVLV Sbjct: 30 DIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWYGQGKDYNVLV 89 Query: 239 MDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRR 418 MDLLGPSLEDLFNFCSR+ ++KTVLMLADQMI+R+E+VH+K+F+HRDIKPDNFLMG+GR Sbjct: 90 MDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRH 149 Query: 419 ANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGY 598 N++++IDFGLAKKYRD T QHIPYRE+KNLTGTARYAS+N HLGIEQSRRDD+ESLGY Sbjct: 150 CNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGY 209 Query: 599 VLMYF 613 VLMYF Sbjct: 210 VLMYF 214
>KIN20_CAEEL (Q20471) Casein kinase I isoform delta (EC 2.7.11.1) (Protein| kinase 20) Length = 497 Score = 303 bits (776), Expect = 3e-82 Identities = 143/185 (77%), Positives = 164/185 (88%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLV 238 +IYLG NIQTNEEV +KLE VK+KHPQL ES++YRI+ GG GIP +RW G EGDYNV+V Sbjct: 204 DIYLGQNIQTNEEVAVKLECVKSKHPQLHIESRLYRIMLGGIGIPEIRWCGQEGDYNVMV 263 Query: 239 MDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRR 418 M+LLGPSLEDLFNFC RK SLKTVL+LADQM++RVEF+H + ++HRDIKPDNFLMGLG+R Sbjct: 264 MELLGPSLEDLFNFCQRKFSLKTVLLLADQMLSRVEFIHCRDYIHRDIKPDNFLMGLGKR 323 Query: 419 ANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGY 598 N VY+IDFGLAK+YRD S HQHI YRENKNLTGTARYAS+NTH GIEQSRRDD+ESLGY Sbjct: 324 GNLVYIIDFGLAKRYRD-SKHQHIAYRENKNLTGTARYASINTHRGIEQSRRDDIESLGY 382 Query: 599 VLMYF 613 V MYF Sbjct: 383 VFMYF 387
>KC1_EIMTE (Q6QNL9) Casein kinase I (EC 2.7.11.1)| Length = 335 Score = 303 bits (775), Expect = 3e-82 Identities = 139/185 (75%), Positives = 167/185 (90%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLV 238 +IYLGTNI T +EV IKLE+V+++HPQL+YESK+Y+IL GG GIP + W+G+EGDYNV++ Sbjct: 22 DIYLGTNISTGDEVAIKLESVRSRHPQLIYESKLYKILTGGIGIPTLYWYGIEGDYNVMI 81 Query: 239 MDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRR 418 ++LLGPSLEDLF+ C+RKLSLKTVLMLADQM+NR+EFVHS+ F+HRDIKPDNFL+G G++ Sbjct: 82 IELLGPSLEDLFSICNRKLSLKTVLMLADQMLNRIEFVHSRHFIHRDIKPDNFLIGRGKK 141 Query: 419 ANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGY 598 + V+ IDFGLAKKYRD T HIPYRE KNLTGTARYASVNTHLGIEQSRRDDLE+LGY Sbjct: 142 MSIVFAIDFGLAKKYRDPRTQSHIPYREGKNLTGTARYASVNTHLGIEQSRRDDLEALGY 201 Query: 599 VLMYF 613 VLMYF Sbjct: 202 VLMYF 206
>YKL1_CAEEL (P42168) Putative casein kinase I C03C10.1 in chromosome III (EC| 2.7.11.1) Length = 341 Score = 303 bits (775), Expect = 3e-82 Identities = 138/185 (74%), Positives = 165/185 (89%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLV 238 +IY+ N+ EEV IKLE+ + +HPQLLYESK+YRILQGG GIP++RW+G E +YNVLV Sbjct: 29 DIYVSINVTNGEEVAIKLESNRARHPQLLYESKVYRILQGGVGIPHIRWYGTEREYNVLV 88 Query: 239 MDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRR 418 MDLLGPSLEDLFNFCSR+ ++KTVLMLADQMI R+E+VH K+F+HRDIKPDNFLMG+GR Sbjct: 89 MDLLGPSLEDLFNFCSRRFTMKTVLMLADQMIGRIEYVHVKNFIHRDIKPDNFLMGIGRH 148 Query: 419 ANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGY 598 N++++IDFGLAKKYRD+ T HIPYRE+KNLTGTARYAS+N HLGIEQSRRDD+ESLGY Sbjct: 149 CNKLFLIDFGLAKKYRDSRTRTHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGY 208 Query: 599 VLMYF 613 VLMYF Sbjct: 209 VLMYF 213
>DCO_DROME (O76324) Discs overgrown protein kinase (EC 2.7.11.1) (Protein| double-time) Length = 440 Score = 301 bits (772), Expect = 8e-82 Identities = 140/185 (75%), Positives = 164/185 (88%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLV 238 +IYLGT I T EEV IKLE ++TKHPQL ESK Y+ +QGG GIP + W G EGDYNV+V Sbjct: 22 DIYLGTTINTGEEVAIKLECIRTKHPQLHIESKFYKTMQGGIGIPRIIWCGSEGDYNVMV 81 Query: 239 MDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRR 418 M+LLGPSLEDLFNFCSR+ SLKTVL+LADQMI+R++++HS+ F+HRDIKPDNFLMGLG++ Sbjct: 82 MELLGPSLEDLFNFCSRRFSLKTVLLLADQMISRIDYIHSRDFIHRDIKPDNFLMGLGKK 141 Query: 419 ANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGY 598 N VY+IDFGLAKK+RD + +HIPYRENKNLTGTARYAS+NTHLGIEQSRRDDLESLGY Sbjct: 142 GNLVYIIDFGLAKKFRDARSLKHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGY 201 Query: 599 VLMYF 613 VLMYF Sbjct: 202 VLMYF 206
>KC1AL_HUMAN (Q8N752) Casein kinase I isoform alpha-like (EC 2.7.11.1)| (CKI-alpha-like) (CK1) Length = 337 Score = 292 bits (747), Expect = 6e-79 Identities = 135/185 (72%), Positives = 159/185 (85%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLV 238 ++YLG EEV +KLE+ K KHPQLLYESK+Y ILQGG GIP++ W+G E D NVLV Sbjct: 30 DVYLGITTTNGEEVAVKLESQKVKHPQLLYESKLYTILQGGVGIPHMHWYGQEKDNNVLV 89 Query: 239 MDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRR 418 MDLLGPSLEDLFNFCSR+ ++KTVLMLADQMI+R+E+VH+K+FLHRDIKPDNFLMG GR Sbjct: 90 MDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFLHRDIKPDNFLMGTGRH 149 Query: 419 ANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGY 598 N++++IDFGLAKKYRD T QHIPYRE+K+L GT RYAS+N HLGIEQSRRDD+ESLGY Sbjct: 150 CNKLFLIDFGLAKKYRDNRTRQHIPYREDKHLIGTVRYASINAHLGIEQSRRDDMESLGY 209 Query: 599 VLMYF 613 V MYF Sbjct: 210 VFMYF 214
>HRR25_YEAST (P29295) Casein kinase I homolog HRR25 (EC 2.7.11.1)| Length = 494 Score = 291 bits (745), Expect = 1e-78 Identities = 133/185 (71%), Positives = 164/185 (88%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLV 238 +IY GTN+ + EEV IKLE+++++HPQL YES++YR L GG GIP +RWFG EG+YN +V Sbjct: 22 DIYHGTNLISGEEVAIKLESIRSRHPQLDYESRVYRYLSGGVGIPFIRWFGREGEYNAMV 81 Query: 239 MDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRR 418 +DLLGPSLEDLFN+C R+ S KTV+MLA QM R++++H +SF+HRDIKPDNFLMG+GRR Sbjct: 82 IDLLGPSLEDLFNYCHRRFSFKTVIMLALQMFCRIQYIHGRSFIHRDIKPDNFLMGVGRR 141 Query: 419 ANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGY 598 + V+VIDFGL+KKYRD +TH+HIPYRENK+LTGTARYASVNTHLGIEQSRRDDLESLGY Sbjct: 142 GSTVHVIDFGLSKKYRDFNTHRHIPYRENKSLTGTARYASVNTHLGIEQSRRDDLESLGY 201 Query: 599 VLMYF 613 VL+YF Sbjct: 202 VLIYF 206
>KC1_PLAYO (Q7RBX5) Casein kinase I (EC 2.7.11.1)| Length = 323 Score = 288 bits (738), Expect = 7e-78 Identities = 128/185 (69%), Positives = 162/185 (87%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLV 238 +IY+ +I T EE +KLE+ ++KHPQLLYESK+Y+IL GG G+P V W+G+EGD+ ++V Sbjct: 22 DIYVAKDIVTMEEFAVKLESTRSKHPQLLYESKLYKILGGGIGVPKVYWYGIEGDFTIMV 81 Query: 239 MDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRR 418 +DLLGPSLEDLF C+RK SLKTVLM ADQM+NR+E+VHSK+F+HRDIKPDNFL+G G++ Sbjct: 82 LDLLGPSLEDLFTLCNRKFSLKTVLMTADQMLNRIEYVHSKNFIHRDIKPDNFLIGRGKK 141 Query: 419 ANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGY 598 +++IDFGLAKKYRD+ +H HIPY+E KNLTGTARYAS+NTHLGIEQSRRDD+E+LGY Sbjct: 142 VTLIHIIDFGLAKKYRDSRSHTHIPYKEGKNLTGTARYASINTHLGIEQSRRDDIEALGY 201 Query: 599 VLMYF 613 VLMYF Sbjct: 202 VLMYF 206
>KC1_PLAF7 (Q8IHZ9) Casein kinase I (EC 2.7.11.1)| Length = 323 Score = 288 bits (738), Expect = 7e-78 Identities = 128/185 (69%), Positives = 162/185 (87%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLV 238 +IY+ +I T EE +KLE+ ++KHPQLLYESK+Y+IL GG G+P V W+G+EGD+ ++V Sbjct: 22 DIYVAKDIVTMEEFAVKLESTRSKHPQLLYESKLYKILGGGIGVPKVYWYGIEGDFTIMV 81 Query: 239 MDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRR 418 +DLLGPSLEDLF C+RK SLKTVLM ADQM+NR+E+VHSK+F+HRDIKPDNFL+G G++ Sbjct: 82 LDLLGPSLEDLFTLCNRKFSLKTVLMTADQMLNRIEYVHSKNFIHRDIKPDNFLIGRGKK 141 Query: 419 ANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGY 598 +++IDFGLAKKYRD+ +H HIPY+E KNLTGTARYAS+NTHLGIEQSRRDD+E+LGY Sbjct: 142 VTLIHIIDFGLAKKYRDSRSHTHIPYKEGKNLTGTARYASINTHLGIEQSRRDDIEALGY 201 Query: 599 VLMYF 613 VLMYF Sbjct: 202 VLMYF 206
>KC1_PLAF4 (O15726) Casein kinase I (EC 2.7.11.1)| Length = 324 Score = 281 bits (718), Expect = 1e-75 Identities = 125/185 (67%), Positives = 159/185 (85%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLV 238 +IY+ +I T EE +KLE+ ++KHPQLLYESK+Y+IL GG G+P V W+G+EGD+ ++V Sbjct: 22 DIYVAKDIVTMEEFAVKLESTRSKHPQLLYESKLYKILGGGIGVPKVYWYGIEGDFTIMV 81 Query: 239 MDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRR 418 +DLLGPSLEDLF C+RK SLKTV M ADQM+NR+E+VHSK+F+HRDIKPDNFL+G G++ Sbjct: 82 LDLLGPSLEDLFTLCNRKFSLKTVRMTADQMLNRIEYVHSKNFIHRDIKPDNFLIGRGKK 141 Query: 419 ANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGY 598 +++IDFGLAKKYRD+ +H PY+E KNLTGTARYAS+NTHLGIEQSRRDD+E+LGY Sbjct: 142 VTLIHIIDFGLAKKYRDSRSHTSYPYKEGKNLTGTARYASINTHLGIEQSRRDDIEALGY 201 Query: 599 VLMYF 613 VLMYF Sbjct: 202 VLMYF 206
>KC1A_DROME (P54367) Casein kinase I isoform alpha (EC 2.7.11.1) (CKI-alpha)| (DmCK1) Length = 337 Score = 278 bits (712), Expect = 7e-75 Identities = 128/185 (69%), Positives = 156/185 (84%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLV 238 +IYLG +IQ+ EEV IK+E+ +HPQLLYE+K+YRIL GG G P +R G E ++N LV Sbjct: 33 DIYLGMSIQSGEEVAIKMESAHARHPQLLYEAKLYRILSGGVGFPRIRHHGKEKNFNTLV 92 Query: 239 MDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRR 418 MDLLGPSLEDLFNFC+R ++KTVLML DQMI R+E++H K F+HRDIKPDNFLMG+GR Sbjct: 93 MDLLGPSLEDLFNFCTRHFTIKTVLMLVDQMIGRLEYIHLKCFIHRDIKPDNFLMGIGRH 152 Query: 419 ANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGY 598 N++++IDFGLAKK+RD T HI YRE+KNLTGTARYAS+N HLGIEQSRRDD+ESLGY Sbjct: 153 CNKLFLIDFGLAKKFRDPHTRHHIVYREDKNLTGTARYASINAHLGIEQSRRDDMESLGY 212 Query: 599 VLMYF 613 V+MYF Sbjct: 213 VMMYF 217
>HHP2_SCHPO (P40236) Casein kinase I homolog hhp2 (EC 2.7.11.1)| Length = 400 Score = 274 bits (700), Expect = 2e-73 Identities = 130/185 (70%), Positives = 154/185 (83%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLV 238 +IYLG N E+V +KLE +K +H QL YE ++Y IL+G GIP +RWFGV YN +V Sbjct: 25 QIYLGLNTVNGEQVAVKLEPLKARHHQLEYEFRVYNILKGNIGIPTIRWFGVTNSYNAMV 84 Query: 239 MDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRR 418 MDLLGPSLEDLF +C RK +LKTVL+LADQ+I+R+E+VHSKSFLHRDIKPDNFLM + Sbjct: 85 MDLLGPSLEDLFCYCGRKFTLKTVLLLADQLISRIEYVHSKSFLHRDIKPDNFLM--KKH 142 Query: 419 ANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGY 598 +N V +IDFGLAKKYRD TH HIPYR+NKNLTGTARYAS+NTH+GIEQSRRDDLESLGY Sbjct: 143 SNVVTMIDFGLAKKYRDFKTHVHIPYRDNKNLTGTARYASINTHIGIEQSRRDDLESLGY 202 Query: 599 VLMYF 613 VL+YF Sbjct: 203 VLLYF 207
>KC1B_BOVIN (P35507) Casein kinase I isoform beta (EC 2.7.11.1) (CKI-beta)| Length = 336 Score = 261 bits (666), Expect = 1e-69 Identities = 118/184 (64%), Positives = 152/184 (82%) Frame = +2 Query: 62 IYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLVM 241 +YL ++ +E+V +KLE+ T+ P+LL+E ++Y LQGG GIP +RW+G E DYNVLVM Sbjct: 31 VYLAIDLTNHEQVAVKLESENTRQPRLLHEKELYNFLQGGVGIPQIRWYGQETDYNVLVM 90 Query: 242 DLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRA 421 DLLGPSLEDLFNFCSR+ S+KTVLMLADQMI+R+E+VHS++ +HRDIKPDNFLMG G + Sbjct: 91 DLLGPSLEDLFNFCSRRFSMKTVLMLADQMISRIEYVHSRNLIHRDIKPDNFLMGTGPQW 150 Query: 422 NQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGYV 601 +++++DFGLAKKYRD T QHIP+R K+ GT AS++ HLGIEQSRRDD+ES+GYV Sbjct: 151 KKLFLVDFGLAKKYRDNRTGQHIPHRSGKSFIGTPFCASISAHLGIEQSRRDDMESIGYV 210 Query: 602 LMYF 613 LMYF Sbjct: 211 LMYF 214
>CKI1_SCHPO (P40233) Casein kinase I homolog 1 (EC 2.7.11.1)| Length = 446 Score = 231 bits (589), Expect = 1e-60 Identities = 113/186 (60%), Positives = 142/186 (76%), Gaps = 2/186 (1%) Frame = +2 Query: 62 IYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLVM 241 I+ GTN+ N++V IK E ++ PQL E + Y++L G TGIPNV +FG EG +N+LV+ Sbjct: 26 IFEGTNLLNNQQVAIKFEPRRSDAPQLRDEYRTYKLLAGCTGIPNVYYFGQEGLHNILVI 85 Query: 242 DLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGL--GR 415 DLLGPSLEDL + C RK S+KTV M A QM+ RV+ +H KS ++RDIKPDNFL+G + Sbjct: 86 DLLGPSLEDLLDLCGRKFSVKTVAMAAKQMLARVQSIHEKSLVYRDIKPDNFLIGRPNSK 145 Query: 416 RANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLG 595 AN +YV+DFG+ K YRD T QHIPYRE KNL+GTARY S+NTHLG EQSRRDDLE+LG Sbjct: 146 NANMIYVVDFGMVKFYRDPVTKQHIPYREKKNLSGTARYMSINTHLGREQSRRDDLEALG 205 Query: 596 YVLMYF 613 +V MYF Sbjct: 206 HVFMYF 211
>KC1G3_RAT (Q62763) Casein kinase I isoform gamma-3 (EC 2.7.11.1) (CKI-gamma| 3) Length = 448 Score = 230 bits (586), Expect = 3e-60 Identities = 114/187 (60%), Positives = 148/187 (79%), Gaps = 2/187 (1%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLV 238 E+ LG N+ TNE V IKLE +K++ PQL E + Y+ L G GIP V +FG G YN +V Sbjct: 56 ELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQVYYFGPCGKYNAMV 115 Query: 239 MDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGL-GR 415 ++LLGPSLEDLF+ C R SLKTVLM+A Q+I+R+E+VHSK+ ++RD+KP+NFL+G G Sbjct: 116 LELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGN 175 Query: 416 RANQV-YVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESL 592 +A QV ++IDFGLAK+Y D T +HIPYRE+K+LTGTARY S+NTHLG EQSRRDDLE+L Sbjct: 176 KAQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEAL 235 Query: 593 GYVLMYF 613 G++ MYF Sbjct: 236 GHMFMYF 242
>KC1G3_BOVIN (P35509) Casein kinase I isoform gamma-3 (EC 2.7.11.1) (CKI-gamma| 3) (Fragment) Length = 276 Score = 228 bits (582), Expect = 8e-60 Identities = 113/187 (60%), Positives = 147/187 (78%), Gaps = 2/187 (1%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLV 238 E+ LG N+ TNE V IKLE +K++ PQL E + Y+ L G GIP V +FG G YN +V Sbjct: 42 ELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQVYYFGPCGKYNAMV 101 Query: 239 MDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGL-GR 415 ++LLGPSLEDLF+ C R SLKTVLM+A Q+I+R+E+VHSK+ ++RD+KP+NFL+G G Sbjct: 102 LELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGN 161 Query: 416 RANQV-YVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESL 592 + QV ++IDFGLAK+Y D T +HIPYRE+K+LTGTARY S+NTHLG EQSRRDDLE+L Sbjct: 162 KTQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEAL 221 Query: 593 GYVLMYF 613 G++ MYF Sbjct: 222 GHMFMYF 228
>KC1G3_HUMAN (Q9Y6M4) Casein kinase I isoform gamma-3 (EC 2.7.11.1) (CKI-gamma| 3) Length = 447 Score = 228 bits (582), Expect = 8e-60 Identities = 113/187 (60%), Positives = 147/187 (78%), Gaps = 2/187 (1%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLV 238 E+ LG N+ TNE V IKLE +K++ PQL E + Y+ L G GIP V +FG G YN +V Sbjct: 56 ELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQVYYFGPCGKYNAMV 115 Query: 239 MDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGL-GR 415 ++LLGPSLEDLF+ C R SLKTVLM+A Q+I+R+E+VHSK+ ++RD+KP+NFL+G G Sbjct: 116 LELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGN 175 Query: 416 RANQV-YVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESL 592 + QV ++IDFGLAK+Y D T +HIPYRE+K+LTGTARY S+NTHLG EQSRRDDLE+L Sbjct: 176 KTQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEAL 235 Query: 593 GYVLMYF 613 G++ MYF Sbjct: 236 GHMFMYF 242
>CKI2_SCHPO (P40234) Casein kinase I homolog 2 (EC 2.7.11.1)| Length = 435 Score = 228 bits (582), Expect = 8e-60 Identities = 111/186 (59%), Positives = 142/186 (76%), Gaps = 2/186 (1%) Frame = +2 Query: 62 IYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLVM 241 I+ G N+ N+ + IK E K++ PQL E + Y++L G GIPNV +FG EG +N+LV+ Sbjct: 26 IFDGMNLLNNQLIAIKFEPKKSEAPQLRDEYRTYKLLVGNAGIPNVYYFGQEGLHNILVI 85 Query: 242 DLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMG--LGR 415 DLLGPSLEDLF +C R+ S+KTV M A QM++RV+ +H K+ ++RDIKPDNFL+G R Sbjct: 86 DLLGPSLEDLFEWCGRRFSVKTVAMTAKQMLSRVQTIHEKNLVYRDIKPDNFLIGRPSSR 145 Query: 416 RANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLG 595 AN VY++DFG+AK YRD T QHIPY E K+L+GTARY S+NTHLG EQSRRDDLESLG Sbjct: 146 NANMVYMVDFGMAKYYRDPKTKQHIPYSERKSLSGTARYMSINTHLGREQSRRDDLESLG 205 Query: 596 YVLMYF 613 +V MYF Sbjct: 206 HVFMYF 211
>KC1G2_RAT (Q62762) Casein kinase I isoform gamma-2 (EC 2.7.11.1) (CKI-gamma| 2) Length = 415 Score = 226 bits (575), Expect = 5e-59 Identities = 108/187 (57%), Positives = 145/187 (77%), Gaps = 2/187 (1%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLV 238 E+ LG N+ TNE V IKLE +K++ PQL E + Y+ L G+P V +FG G YN +V Sbjct: 59 ELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSTTEGVPQVYYFGPCGKYNAMV 118 Query: 239 MDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGL--G 412 ++LLGPSLEDLF+ C R +LKTVLM+A Q+I R+E+VH+KS ++RD+KP+NFL+G Sbjct: 119 LELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGS 178 Query: 413 RRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESL 592 +R + +++IDFGLAK+Y D T +HIPYRE+K+LTGTARY S+NTHLG EQSRRDDLE+L Sbjct: 179 KRQHSIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEAL 238 Query: 593 GYVLMYF 613 G++ MYF Sbjct: 239 GHMFMYF 245
>KC1G2_MOUSE (Q8BVP5) Casein kinase I isoform gamma-2 (EC 2.7.11.1) (CKI-gamma| 2) Length = 415 Score = 226 bits (575), Expect = 5e-59 Identities = 108/187 (57%), Positives = 145/187 (77%), Gaps = 2/187 (1%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLV 238 E+ LG N+ TNE V IKLE +K++ PQL E + Y+ L G+P V +FG G YN +V Sbjct: 59 ELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSTTEGVPQVYYFGPCGKYNAMV 118 Query: 239 MDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGL--G 412 ++LLGPSLEDLF+ C R +LKTVLM+A Q+I R+E+VH+KS ++RD+KP+NFL+G Sbjct: 119 LELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGS 178 Query: 413 RRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESL 592 +R + +++IDFGLAK+Y D T +HIPYRE+K+LTGTARY S+NTHLG EQSRRDDLE+L Sbjct: 179 KRQHSIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEAL 238 Query: 593 GYVLMYF 613 G++ MYF Sbjct: 239 GHMFMYF 245
>KC1G2_HUMAN (P78368) Casein kinase I isoform gamma-2 (EC 2.7.11.1) (CKI-gamma| 2) Length = 415 Score = 225 bits (574), Expect = 7e-59 Identities = 108/187 (57%), Positives = 145/187 (77%), Gaps = 2/187 (1%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLV 238 E+ LG N+ TNE V IKLE +K++ PQL E + Y+ L G+P V +FG G YN +V Sbjct: 59 ELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSATEGVPQVYYFGPCGKYNAMV 118 Query: 239 MDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGL--G 412 ++LLGPSLEDLF+ C R +LKTVLM+A Q+I R+E+VH+KS ++RD+KP+NFL+G Sbjct: 119 LELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGT 178 Query: 413 RRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESL 592 +R + +++IDFGLAK+Y D T +HIPYRE+K+LTGTARY S+NTHLG EQSRRDDLE+L Sbjct: 179 KRQHAIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEAL 238 Query: 593 GYVLMYF 613 G++ MYF Sbjct: 239 GHMFMYF 245
>CKI3_SCHPO (O74135) Casein kinase I homolog 3 (EC 2.7.11.1)| Length = 439 Score = 223 bits (568), Expect = 3e-58 Identities = 105/186 (56%), Positives = 141/186 (75%), Gaps = 2/186 (1%) Frame = +2 Query: 62 IYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLVM 241 ++ G N+ N+ + +K E+ K++ PQL E Y++L G GIP+V ++G EG YN+LVM Sbjct: 29 LFQGVNLINNQPIALKFESRKSEVPQLRDEYLTYKLLMGLPGIPSVYYYGQEGMYNLLVM 88 Query: 242 DLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGL--GR 415 DLLGPSLEDLF++C R+ S KTV M+A QMI R++ VH + F++RDIKPDNFL+G + Sbjct: 89 DLLGPSLEDLFDYCGRRFSPKTVAMIAKQMITRIQSVHERHFIYRDIKPDNFLIGFPGSK 148 Query: 416 RANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLG 595 N +Y +DFG+AK+YRD TH H PY E+K+L+GTARY S+NTHLG EQSRRDDLES+G Sbjct: 149 TENVIYAVDFGMAKQYRDPKTHVHRPYNEHKSLSGTARYMSINTHLGREQSRRDDLESMG 208 Query: 596 YVLMYF 613 +V MYF Sbjct: 209 HVFMYF 214
>KC1G1_HUMAN (Q9HCP0) Casein kinase I isoform gamma-1 (EC 2.7.11.1) (CKI-gamma| 1) Length = 422 Score = 222 bits (566), Expect = 6e-58 Identities = 107/188 (56%), Positives = 147/188 (78%), Gaps = 3/188 (1%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRIL-QGGTGIPNVRWFGVEGDYNVL 235 E+ LG N+ TNE V IKLE +K++ PQL E + Y+ L G G+P V +FG G YN + Sbjct: 57 ELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAGEGLPQVYYFGPCGKYNAM 116 Query: 236 VMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGL-- 409 V++LLGPSLEDLF+ C R +LKTVLM+A Q+++R+E+VHSK+ ++RD+KP+NFL+G Sbjct: 117 VLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQG 176 Query: 410 GRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLES 589 ++ + +++IDFGLAK+Y D T +HIPYRE+K+LTGTARY S+NTHLG EQSRRDDLE+ Sbjct: 177 NKKEHVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEA 236 Query: 590 LGYVLMYF 613 LG++ MYF Sbjct: 237 LGHMFMYF 244
>KC1G1_RAT (Q62761) Casein kinase I isoform gamma-1 (EC 2.7.11.1) (CKI-gamma| 1) Length = 390 Score = 222 bits (566), Expect = 6e-58 Identities = 107/188 (56%), Positives = 147/188 (78%), Gaps = 3/188 (1%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRIL-QGGTGIPNVRWFGVEGDYNVL 235 E+ LG N+ TNE V IKLE +K++ PQL E + Y+ L G G+P V +FG G YN + Sbjct: 57 ELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAGEGLPQVYYFGPCGKYNAM 116 Query: 236 VMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGL-- 409 V++LLGPSLEDLF+ C R +LKTVLM+A Q+++R+E+VHSK+ ++RD+KP+NFL+G Sbjct: 117 VLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQG 176 Query: 410 GRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLES 589 ++ + +++IDFGLAK+Y D T +HIPYRE+K+LTGTARY S+NTHLG EQSRRDDLE+ Sbjct: 177 NKKEHVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEA 236 Query: 590 LGYVLMYF 613 LG++ MYF Sbjct: 237 LGHMFMYF 244
>KC1G1_MOUSE (Q8BTH8) Casein kinase I isoform gamma-1 (EC 2.7.11.1) (CKI-gamma| 1) Length = 459 Score = 222 bits (566), Expect = 6e-58 Identities = 107/188 (56%), Positives = 147/188 (78%), Gaps = 3/188 (1%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRIL-QGGTGIPNVRWFGVEGDYNVL 235 E+ LG N+ TNE V IKLE +K++ PQL E + Y+ L G G+P V +FG G YN + Sbjct: 57 ELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAGEGLPQVYYFGPCGKYNAM 116 Query: 236 VMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGL-- 409 V++LLGPSLEDLF+ C R +LKTVLM+A Q+++R+E+VHSK+ ++RD+KP+NFL+G Sbjct: 117 VLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQG 176 Query: 410 GRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLES 589 ++ + +++IDFGLAK+Y D T +HIPYRE+K+LTGTARY S+NTHLG EQSRRDDLE+ Sbjct: 177 NKKEHVIHIIDFGLAKEYVDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEA 236 Query: 590 LGYVLMYF 613 LG++ MYF Sbjct: 237 LGHMFMYF 244
>RAG8_KLULA (P40230) Casein kinase I homolog RAG8 (EC 2.7.11.1)| Length = 536 Score = 213 bits (543), Expect = 3e-55 Identities = 106/186 (56%), Positives = 136/186 (73%), Gaps = 2/186 (1%) Frame = +2 Query: 62 IYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLVM 241 ++ G N+ N V IK E KT PQL E + Y+IL G GIP +FG EG +N+LV+ Sbjct: 91 LFEGVNMINNVPVAIKFEPRKTDAPQLKDEYRTYKILSGSEGIPQAYYFGQEGLHNILVI 150 Query: 242 DLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRR- 418 DLLGPSLEDLF++C R+ S+KTV+ +A QMI +E +H ++RDIKPDNFL+G + Sbjct: 151 DLLGPSLEDLFDWCGRRFSIKTVVHVAIQMITLIEELHDHDLIYRDIKPDNFLIGRPNQP 210 Query: 419 -ANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLG 595 AN V++IDFG+AK YRD T QHIPYRE K+L+GTARY S+NTHLG EQSRRDD+E+LG Sbjct: 211 DANMVHLIDFGMAKLYRDPKTKQHIPYREKKSLSGTARYMSINTHLGREQSRRDDMEALG 270 Query: 596 YVLMYF 613 +V YF Sbjct: 271 HVFFYF 276
>KC11_YEAST (P23291) Casein kinase I homolog 1 (EC 2.7.11.1)| Length = 538 Score = 213 bits (542), Expect = 4e-55 Identities = 106/186 (56%), Positives = 138/186 (74%), Gaps = 2/186 (1%) Frame = +2 Query: 62 IYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLVM 241 ++ GTN+ V IK E KT+ PQL E K Y+IL G IP +FG EG +N+LV+ Sbjct: 83 LFEGTNMINGVPVAIKFEPRKTEAPQLRDEYKTYKILNGTPNIPYAYYFGQEGLHNILVI 142 Query: 242 DLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRR- 418 DLLGPSLEDLF++C RK S+KTV+ +A QMI +E +H+ ++RDIKPDNFL+G + Sbjct: 143 DLLGPSLEDLFDWCGRKFSVKTVVQVAVQMITLIEDLHAHDLIYRDIKPDNFLIGRPGQP 202 Query: 419 -ANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLG 595 AN +++IDFG+AK+YRD T QHIPYRE K+L+GTARY S+NTHLG EQSRRDD+E+LG Sbjct: 203 DANNIHLIDFGMAKQYRDPKTKQHIPYREKKSLSGTARYMSINTHLGREQSRRDDMEALG 262 Query: 596 YVLMYF 613 +V YF Sbjct: 263 HVFFYF 268
>KC12_YEAST (P23292) Casein kinase I homolog 2 (EC 2.7.11.1)| Length = 546 Score = 212 bits (540), Expect = 6e-55 Identities = 105/186 (56%), Positives = 140/186 (75%), Gaps = 2/186 (1%) Frame = +2 Query: 62 IYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLVM 241 ++ GTN+ V IK E KT+ PQL E + Y+IL G GIP +FG EG +N+LV+ Sbjct: 90 LFEGTNMINGLPVAIKFEPRKTEAPQLKDEYRTYKILAGTPGIPQEYYFGQEGLHNILVI 149 Query: 242 DLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRR- 418 DLLGPSLEDLF++C R+ S+KTV+ +A QMI +E +H+ ++RDIKPDNFL+G + Sbjct: 150 DLLGPSLEDLFDWCGRRFSVKTVVQVAVQMITLIEDLHAHDLIYRDIKPDNFLIGRPGQP 209 Query: 419 -ANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLG 595 AN+V++IDFG+AK+YRD T QHIPYRE K+L+GTARY S+NTHLG EQSRRDD+E++G Sbjct: 210 DANKVHLIDFGMAKQYRDPKTKQHIPYREKKSLSGTARYMSINTHLGREQSRRDDMEAMG 269 Query: 596 YVLMYF 613 +V YF Sbjct: 270 HVFFYF 275
>KC1A_PIG (O19175) Casein kinase I isoform alpha (EC 2.7.11.1) (CKI-alpha)| (CK1) (Fragment) Length = 125 Score = 209 bits (531), Expect = 7e-54 Identities = 93/124 (75%), Positives = 115/124 (92%) Frame = +2 Query: 92 EEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLVMDLLGPSLEDL 271 EEV +KLE+ K +HPQLLYESK+Y+ILQGG GIP++RW+G E DYNVLVMDLLGPSLEDL Sbjct: 2 EEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDL 61 Query: 272 FNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGL 451 FNFCSR+ ++KTVLMLADQMI+R+E+VH+K+F+HRDIKPDNFLMG+GR N++++IDFGL Sbjct: 62 FNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGL 121 Query: 452 AKKY 463 AKKY Sbjct: 122 AKKY 125
>KC13_YEAST (P39962) Casein kinase I homolog 3 (EC 2.7.11.1)| Length = 524 Score = 207 bits (526), Expect = 3e-53 Identities = 105/196 (53%), Positives = 131/196 (66%), Gaps = 18/196 (9%) Frame = +2 Query: 80 IQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLVMDLLGPS 259 I NE V IK E + PQL E + YRIL G GIP+ +FG EG +N+L++DLLGPS Sbjct: 51 IMANEPVAIKFEPRHSDAPQLRDEFRAYRILNGCVGIPHAYYFGQEGMHNILIIDLLGPS 110 Query: 260 LEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRR------- 418 LEDLF +C RK S+KT M+A QMI+RV +H ++RDIKPDNFL+ +R Sbjct: 111 LEDLFEWCGRKFSVKTTCMVAKQMIDRVRAIHDHDLIYRDIKPDNFLISQYQRISPEGKV 170 Query: 419 -----------ANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQ 565 N +Y++DFG+AK+YRD T QHIPYRE K+L+GTARY S+NTH G EQ Sbjct: 171 IKSCASSSNNDPNLIYMVDFGMAKQYRDPRTKQHIPYRERKSLSGTARYMSINTHFGREQ 230 Query: 566 SRRDDLESLGYVLMYF 613 SRRDDLESLG+V YF Sbjct: 231 SRRDDLESLGHVFFYF 246
>KC1D_RABIT (P81123) Casein kinase I isoform delta (EC 2.7.11.1) (CKI-delta)| (CKId) (Fragment) Length = 81 Score = 148 bits (373), Expect = 1e-35 Identities = 69/78 (88%), Positives = 73/78 (93%) Frame = +2 Query: 380 IKPDNFLMGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGI 559 I PDNFLMGLG++ N VY+IDFGLAKKYRD THQHIPYRENKNLTGTARYAS+NTHLGI Sbjct: 2 IFPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGI 61 Query: 560 EQSRRDDLESLGYVLMYF 613 EQSRRDDLESLGYVLMYF Sbjct: 62 EQSRRDDLESLGYVLMYF 79
>TTBK1_HUMAN (Q5TCY1) Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau| kinase) Length = 1321 Score = 115 bits (287), Expect = 1e-25 Identities = 74/187 (39%), Positives = 99/187 (52%), Gaps = 2/187 (1%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLV 238 EIY ++ T E V +K+E+ + L E + + LQG + G +N +V Sbjct: 47 EIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVV 106 Query: 239 MDLLGPSLEDLFNFCSR-KLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMG-LG 412 M L G +L DL R +L T L L Q++ +E +HS FLHRDIKP NF MG L Sbjct: 107 MQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLP 166 Query: 413 RRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESL 592 + Y++DFGLA++Y +T T P R GT RYASVN H E R DDL SL Sbjct: 167 STYRKCYMLDFGLARQYTNT-TGDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSL 225 Query: 593 GYVLMYF 613 Y+L+ F Sbjct: 226 FYMLVEF 232
>TTBK2_HUMAN (Q6IQ55) Tau-tubulin kinase 2 (EC 2.7.11.1)| Length = 1244 Score = 109 bits (272), Expect = 7e-24 Identities = 70/187 (37%), Positives = 98/187 (52%), Gaps = 2/187 (1%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLV 238 EIY ++ T E V +K+E+ + L E + + LQG + G +N +V Sbjct: 34 EIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVV 93 Query: 239 MDLLGPSLEDLFNFCSR-KLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMG-LG 412 M L G +L DL SR ++ T L L Q++ +E +HS FLHRDIKP NF MG Sbjct: 94 MQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAMGRFP 153 Query: 413 RRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESL 592 + Y++DFGLA+++ + S P R GT RYAS+N H E R DDL SL Sbjct: 154 STCRKCYMLDFGLARQFTN-SCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDLWSL 212 Query: 593 GYVLMYF 613 Y+L+ F Sbjct: 213 FYMLVEF 219
>TTBK2_MOUSE (Q3UVR3) Tau-tubulin kinase 2| Length = 1243 Score = 108 bits (269), Expect = 2e-23 Identities = 69/187 (36%), Positives = 98/187 (52%), Gaps = 2/187 (1%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLV 238 EIY ++ T E V +K+E+ + L E + + LQG + G +N +V Sbjct: 34 EIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVV 93 Query: 239 MDLLGPSLEDLFNFCSR-KLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMG-LG 412 M L G +L DL SR ++ T L L Q++ +E +HS FLHRDIKP NF MG Sbjct: 94 MQLQGRNLADLRRSQSRGTFTISTTLRLGKQILESIESIHSVGFLHRDIKPSNFAMGRFP 153 Query: 413 RRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESL 592 + +++DFGLA+++ + S P R GT RYAS+N H E R DDL SL Sbjct: 154 STCRKCFMLDFGLARQFTN-SCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDLWSL 212 Query: 593 GYVLMYF 613 Y+L+ F Sbjct: 213 FYMLVEF 219
>YKL2_CAEEL (P42169) Putative casein kinase I C03C10.2 in chromosome III (EC| 2.7.11.1) Length = 363 Score = 93.6 bits (231), Expect = 4e-19 Identities = 60/190 (31%), Positives = 106/190 (55%), Gaps = 10/190 (5%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLE-----NVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGD 223 +I++ +++ N+E +K+E V TK +++ E ++ +QG T IP + G Sbjct: 85 QIFMVMDVKKNDERAMKIEPKLRAEVITK--RMIMEQQVLMKMQGKTHIPTMYASGFNDQ 142 Query: 224 YNVLVMDLLGPSLEDLFNFCSR----KLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPD 391 +N ++M LL ++ D F R +LS +TV +A Q +N ++ +H ++HRD+KP Sbjct: 143 FNFIIMQLLSMNVGD---FRKRSPLGRLSKETVGRIAYQTLNALKDIHDMGYVHRDVKPA 199 Query: 392 NFLMGL-GRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQS 568 N G+ + + +Y++DFGL ++++ T + IP+R N GT RY SV H +EQ+ Sbjct: 200 NICFGVHAQNRHILYLLDFGLVRRFK-TESGVCIPWRINAGFKGTERYVSVRVHEKLEQT 258 Query: 569 RRDDLESLGY 598 DD S+ Y Sbjct: 259 PWDDAFSVLY 268
>V212_FOWPV (Q9J523) Probable serine/threonine-protein kinase FPV212 (EC| 2.7.11.1) Length = 303 Score = 90.9 bits (224), Expect = 3e-18 Identities = 48/145 (33%), Positives = 80/145 (55%), Gaps = 4/145 (2%) Frame = +2 Query: 185 GIPNVRWFGV----EGDYNVLVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFV 352 GIP+ FG+ +Y ++ LG LE++ + K ++ + LA ++++ ++F+ Sbjct: 93 GIPSFHGFGITIYKNVEYRFAIIQRLGRDLENILSE-KEKFNITVIKKLAIKILDILKFI 151 Query: 353 HSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARY 532 HSK F H DIK N L G + ++VY++D+GLA KY H+ GT + Sbjct: 152 HSKEFSHGDIKAGNILFG--KDDDKVYLVDYGLATKYSSNGKHKEYTINPKNRHNGTMAF 209 Query: 533 ASVNTHLGIEQSRRDDLESLGYVLM 607 S++ H G+ SRR DLESLG+ ++ Sbjct: 210 TSIDAHKGVTVSRRGDLESLGFCML 234
>VRK1_MOUSE (Q80X41) Serine/threonine-protein kinase VRK1 (EC 2.7.11.1)| (Vaccinia-related kinase 1) (Serine/threonine-protein kinase 51PK) Length = 440 Score = 90.1 bits (222), Expect = 5e-18 Identities = 42/128 (32%), Positives = 75/128 (58%) Frame = +2 Query: 224 YNVLVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLM 403 Y ++MD G L+ ++ +++ S KTVL L+ ++++ +E++H ++H DIK N L+ Sbjct: 126 YRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLL 185 Query: 404 GLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDL 583 + +QVY++D+GLA +Y H+ + GT + S++ H G+ SRR DL Sbjct: 186 S-HKNPDQVYLVDYGLAYRYCPDGVHKEYKEDPKRCHDGTLEFTSIDAHKGVAPSRRGDL 244 Query: 584 ESLGYVLM 607 E LGY ++ Sbjct: 245 EILGYCMI 252
>VRK1_HUMAN (Q99986) Serine/threonine-protein kinase VRK1 (EC 2.7.11.1)| (Vaccinia-related kinase 1) Length = 396 Score = 90.1 bits (222), Expect = 5e-18 Identities = 42/128 (32%), Positives = 75/128 (58%) Frame = +2 Query: 224 YNVLVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLM 403 Y ++MD G L+ ++ +++ S KTVL L+ ++++ +E++H ++H DIK N L+ Sbjct: 126 YRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLL 185 Query: 404 GLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDL 583 + +QVY++D+GLA +Y H+ + GT + S++ H G+ SRR DL Sbjct: 186 NY-KNPDQVYLVDYGLAYRYCPEGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPSRRGDL 244 Query: 584 ESLGYVLM 607 E LGY ++ Sbjct: 245 EILGYCMI 252
>YOO1_CAEEL (P34633) Putative serine/threonine-protein kinase ZK507.1 (EC| 2.7.11.1) Length = 331 Score = 88.6 bits (218), Expect = 1e-17 Identities = 51/129 (39%), Positives = 70/129 (54%), Gaps = 1/129 (0%) Frame = +2 Query: 206 FGVEGDYNVLVMDLLGPSLEDL-FNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDI 382 FG + +VM ++GPSLE+L + + T+L Q + + H FLHRDI Sbjct: 58 FGQSPVWKWIVMTIVGPSLEELKMKYKPSDIPPSTILQCGLQTMKAIHDFHQIGFLHRDI 117 Query: 383 KPDNFLMGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIE 562 KP N+ +G G ++ +YV+DFGLA+KYR Q P R + GT RY S +H E Sbjct: 118 KPANYCIGYGSKSETIYVLDFGLARKYR-LPNGQVRPPRPKTKMIGTPRYCSRASHRCEE 176 Query: 563 QSRRDDLES 589 RRDD ES Sbjct: 177 LGRRDDYES 185
>VRK1_BRARE (Q7ZUS1) Serine/threonine-protein kinase VRK1 (EC 2.7.11.1)| (Vaccinia-related kinase 1) Length = 425 Score = 86.7 bits (213), Expect = 5e-17 Identities = 43/128 (33%), Positives = 70/128 (54%) Frame = +2 Query: 224 YNVLVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLM 403 Y +VMD G L+ LF +K S K VL L ++++ +E++H ++H DIK N L+ Sbjct: 127 YRFMVMDRFGTDLQKLFEGNGKKFSRKLVLQLGLRLLDILEYIHDHEYVHADIKASNLLL 186 Query: 404 GLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDL 583 NQV+++D+GLA +Y + + GT + S++ H G+ SRR DL Sbjct: 187 SY-TNPNQVFLVDYGLAYRYAPEGVPKEYKEDPKRCHDGTIEFTSIDAHKGVSPSRRADL 245 Query: 584 ESLGYVLM 607 E +GY ++ Sbjct: 246 EIMGYCMI 253
>VPK1_VACCV (P16913) Serine/threonine-protein kinase 1 (EC 2.7.11.1) (Vaccinia| protein kinase 1) Length = 300 Score = 82.8 bits (203), Expect = 7e-16 Identities = 40/131 (30%), Positives = 79/131 (60%), Gaps = 2/131 (1%) Frame = +2 Query: 221 DYNVLVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFL 400 +Y LV++ LG L+ + + +L ++V+++ +++N ++F+H + + H DIK N + Sbjct: 95 EYRFLVINRLGADLDAVIRANNNRLPKRSVMLIGIEILNTIQFMHEQGYSHGDIKASNIV 154 Query: 401 MGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNL--TGTARYASVNTHLGIEQSRR 574 + + N++Y++D+GL K+ S +H+P+ N N GT + +++H G SRR Sbjct: 155 LDQIDK-NKLYLVDYGLVSKFM--SNGEHVPFIRNPNKMDNGTLEFTPIDSHKGYVVSRR 211 Query: 575 DDLESLGYVLM 607 DLE+LGY ++ Sbjct: 212 GDLETLGYCMI 222
>VPK1_VACCA (O57252) Serine/threonine-protein kinase 1 (EC 2.7.11.1) (Vaccinia| protein kinase 1) Length = 300 Score = 82.8 bits (203), Expect = 7e-16 Identities = 40/131 (30%), Positives = 79/131 (60%), Gaps = 2/131 (1%) Frame = +2 Query: 221 DYNVLVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFL 400 +Y LV++ LG L+ + + +L ++V+++ +++N ++F+H + + H DIK N + Sbjct: 95 EYRFLVINRLGADLDAVIRANNNRLPKRSVMLIGIEILNTIQFMHEQGYSHGDIKASNIV 154 Query: 401 MGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNL--TGTARYASVNTHLGIEQSRR 574 + + N++Y++D+GL K+ S +H+P+ N N GT + +++H G SRR Sbjct: 155 LDQIDK-NKLYLVDYGLVSKFM--SNGEHVPFIRNPNKMDNGTLEFTPIDSHKGYVVSRR 211 Query: 575 DDLESLGYVLM 607 DLE+LGY ++ Sbjct: 212 GDLETLGYCMI 222
>VPK1_VACCC (P20505) Serine/threonine-protein kinase 1 (EC 2.7.11.1) (Vaccinia| protein kinase 1) Length = 300 Score = 82.4 bits (202), Expect = 1e-15 Identities = 40/131 (30%), Positives = 79/131 (60%), Gaps = 2/131 (1%) Frame = +2 Query: 221 DYNVLVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFL 400 +Y LV++ LG L+ + + +L ++V+++ +++N ++F+H + + H DIK N + Sbjct: 95 EYRFLVINRLGVDLDAVIRANNNRLPKRSVMLIGIEILNTIQFMHEQGYSHGDIKASNIV 154 Query: 401 MGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNL--TGTARYASVNTHLGIEQSRR 574 + + N++Y++D+GL K+ S +H+P+ N N GT + +++H G SRR Sbjct: 155 LDQIDK-NKLYLVDYGLVSKFM--SNGEHVPFIRNPNKMDNGTLEFTPIDSHKGYVVSRR 211 Query: 575 DDLESLGYVLM 607 DLE+LGY ++ Sbjct: 212 GDLETLGYCMI 222
>VRK2_HUMAN (Q86Y07) Serine/threonine-protein kinase VRK2 (EC 2.7.11.1)| (Vaccinia-related kinase 2) Length = 508 Score = 81.3 bits (199), Expect = 2e-15 Identities = 42/128 (32%), Positives = 70/128 (54%) Frame = +2 Query: 224 YNVLVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLM 403 Y +VM+ LG L+ + + TVL L +M++ +E++H ++H DIK N L+ Sbjct: 116 YRFMVMERLGIDLQKISGQ-NGTFKKSTVLQLGIRMLDVLEYIHENEYVHGDIKAANLLL 174 Query: 404 GLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDL 583 G + +QVY+ D+GL+ +Y H+ K GT + S++ H G+ SRR D+ Sbjct: 175 GY-KNPDQVYLADYGLSYRYCPNGNHKQYQENPRKGHNGTIEFTSLDAHKGVALSRRSDV 233 Query: 584 ESLGYVLM 607 E LGY ++ Sbjct: 234 EILGYCML 241
>VPK1_VARV (P33800) Serine/threonine-protein kinase 1 (EC 2.7.11.1)| Length = 300 Score = 81.3 bits (199), Expect = 2e-15 Identities = 42/147 (28%), Positives = 85/147 (57%), Gaps = 6/147 (4%) Frame = +2 Query: 185 GIPNVRWFG----VEGDYNVLVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFV 352 G+ + FG + +Y LV++ LG L+ + + +L ++V+++ +++N ++F+ Sbjct: 79 GVITCKAFGLYKSINTEYRFLVINRLGVDLDAVIRANNNRLPKRSVMLVGIEILNTIQFM 138 Query: 353 HSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNL--TGTA 526 H + + H +IK N ++ + N++Y++D+GL K+ S +H+P+ N N GT Sbjct: 139 HEQGYSHGNIKASNIVLDQMDK-NKLYLVDYGLVSKFM--SNGEHVPFIRNPNKMDNGTL 195 Query: 527 RYASVNTHLGIEQSRRDDLESLGYVLM 607 + +++H G SRR DLE+LGY ++ Sbjct: 196 EFTPIDSHKGYVVSRRGDLETLGYCMI 222
>VRK2_MOUSE (Q8BN21) Serine/threonine-protein kinase VRK2 (EC 2.7.11.1)| (Vaccinia-related kinase 2) Length = 503 Score = 80.9 bits (198), Expect = 3e-15 Identities = 49/149 (32%), Positives = 79/149 (53%), Gaps = 6/149 (4%) Frame = +2 Query: 185 GIPNVRWFGVEG----DYNVLVMDLLGPSLEDLF--NFCSRKLSLKTVLMLADQMINRVE 346 GIP FG+ Y +VM+ LG L+ L N +KL TVL L +M++ +E Sbjct: 99 GIPVFYGFGLTDFKGRSYRFMVMERLGIDLQKLLDQNGGFKKL---TVLQLGIRMLDVLE 155 Query: 347 FVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTA 526 ++H ++H DIK N L+ ++VY+ D+GL+ +Y H+ K GT Sbjct: 156 YIHENEYVHGDIKAANLLLDF-TNPDRVYLADYGLSYRYCPNGNHKQYQEDPRKGHNGTI 214 Query: 527 RYASVNTHLGIEQSRRDDLESLGYVLMYF 613 + S++ H G+ SRR D+E LGY ++++ Sbjct: 215 EFTSLDAHKGVAPSRRSDVEILGYCMLHW 243
>KC1D_BOVIN (P35508) Casein kinase I isoform delta (EC 2.7.11.1) (CKI-delta)| (CKId) (Fragment) Length = 42 Score = 79.7 bits (195), Expect = 6e-15 Identities = 35/42 (83%), Positives = 38/42 (90%) Frame = +2 Query: 404 GLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTAR 529 GLG++ N VY+IDFGLAKKYRD THQHIPYRENKNLTGTAR Sbjct: 1 GLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTAR 42
>YMX8_CAEEL (P34516) Putative serine/threonine-protein kinase K06H7.1 (EC| 2.7.11.1) Length = 346 Score = 79.7 bits (195), Expect = 6e-15 Identities = 53/137 (38%), Positives = 74/137 (54%), Gaps = 5/137 (3%) Frame = +2 Query: 209 GVEGDYNVLVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKP 388 G + Y+ +VM LLG SL+ L L++ T + + ++ ++ VH +LHRD+KP Sbjct: 85 GKKERYSYMVMTLLGESLDSLLKKHGPFLNVSTQVRIGICILFGIKQVHDIGYLHRDLKP 144 Query: 389 DNFLMGLGRRANQVY--VIDFGLAKKY---RDTSTHQHIPYRENKNLTGTARYASVNTHL 553 N MG A++ Y V+DFGLA++Y D P RE GTARY SV H Sbjct: 145 ANVAMGCKGSADERYFLVLDFGLARQYIADEDDGLKMRRP-REKTYFRGTARYCSVAMHD 203 Query: 554 GIEQSRRDDLESLGYVL 604 EQ R DDL +L Y+L Sbjct: 204 RYEQGRVDDLWALVYIL 220
>YQI1_CAEEL (Q09503) Hypothetical protein C45G9.1 in chromosome III| Length = 290 Score = 76.6 bits (187), Expect = 5e-14 Identities = 51/151 (33%), Positives = 82/151 (54%), Gaps = 11/151 (7%) Frame = +2 Query: 188 IPNVRWFGVEGDYNVLVMDLLGPSLEDL--FNFCSRK-LSLKTVLMLADQMINRVEFVHS 358 IPN+ +G + +++ +VM LLG +L+DL NF K S T + Q + +++VH Sbjct: 18 IPNLNLYGKKMNFSYMVMTLLGRNLQDLESTNFVVNKGFSRGTWSRVGIQWVYALKYVHY 77 Query: 359 KSFLHRDIKPDNFLMGLGR---RANQVYVIDFGLAKKY-----RDTSTHQHIPYRENKNL 514 F+HR++ N +G + RA ++++DFGL + + R+ I R + Sbjct: 78 NGFIHRNVNTQNLFLGNEKDSERAKIIHILDFGLGRPFARYHARENKWIVRIA-RHSAEF 136 Query: 515 TGTARYASVNTHLGIEQSRRDDLESLGYVLM 607 G+ RYAS N HL EQ R DD+ SL YV++ Sbjct: 137 RGSFRYASPNVHLRKEQGRVDDVWSLPYVII 167
>YOO3_CAEEL (P34635) Putative serine/threonine-protein kinase ZK507.3 (EC| 2.7.11.1) Length = 374 Score = 73.6 bits (179), Expect = 4e-13 Identities = 47/134 (35%), Positives = 67/134 (50%), Gaps = 1/134 (0%) Frame = +2 Query: 191 PNVRWFGVEGDYNVLVMDLLGPSLEDL-FNFCSRKLSLKTVLMLADQMINRVEFVHSKSF 367 P + FG + +VM ++GPSLE+L + + T+L Q + + H F Sbjct: 95 PELIDFGQSPVWKWIVMTIVGPSLEELKMKYKPSDIPPSTILQCGLQTMKAIHDFHQIGF 154 Query: 368 LHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNT 547 LHRDIKP N+ +G G ++ +YV+DFGLA+KYR +P Y S + Sbjct: 155 LHRDIKPANYCIGYGSKSETIYVLDFGLARKYR-------LP----------EWYCSRAS 197 Query: 548 HLGIEQSRRDDLES 589 H E RRDD ES Sbjct: 198 HRCEELGRRDDYES 211
>NHK1_DROME (Q7KRY6) Nucleosomal histone kinase 1 (EC 2.7.11.1) (Protein| baellchen) Length = 599 Score = 70.1 bits (170), Expect = 5e-12 Identities = 47/129 (36%), Positives = 69/129 (53%), Gaps = 1/129 (0%) Frame = +2 Query: 224 YNVLVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLM 403 + +VM G L ++L TV LA QM++ +++HS ++H D+K N L+ Sbjct: 132 HRFIVMPRYGSDLTKFLEQNGKRLPEGTVYRLAIQMLDVYQYMHSNGYVHADLKAANILL 191 Query: 404 GLGR-RANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDD 580 GL + A Q Y++DFGLA + T + P K GT Y S + HLG+ +RR D Sbjct: 192 GLEKGGAAQAYLVDFGLASHF-VTGDFKPDP---KKMHNGTIEYTSRDAHLGV-PTRRAD 246 Query: 581 LESLGYVLM 607 LE LGY L+ Sbjct: 247 LEILGYNLI 255
>KRB2_VACCC (P21098) Probable serine/threonine-protein kinase B12 (EC 2.7.11.1)| Length = 283 Score = 68.9 bits (167), Expect = 1e-11 Identities = 48/145 (33%), Positives = 67/145 (46%), Gaps = 5/145 (3%) Frame = +2 Query: 188 IPNVRWFGVEGDYNVLVMDLLG-----PSLEDLFNFCSRKLSLKTVLMLADQMINRVEFV 352 IP++ G DY V+ LG E +F C MIN +EF+ Sbjct: 84 IPDLYGIGETDDYMFFVIKNLGRVFAPKDTESVFEACVT-------------MINTLEFI 130 Query: 353 HSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARY 532 HS+ F H I+P N L+ R ++ +ID+ K S + HI Y E+ +G Y Sbjct: 131 HSRGFTHGKIEPRNILI----RNKRLSLIDYSRTNKLYK-SGNSHIDYNEDMITSGNINY 185 Query: 533 ASVNTHLGIEQSRRDDLESLGYVLM 607 V+ HLG SRR DLE LGY ++ Sbjct: 186 MCVDNHLGATVSRRGDLEMLGYCMI 210
>KRB2_VACCV (P24362) Probable serine/threonine-protein kinase B12 (EC 2.7.11.1)| Length = 283 Score = 68.6 bits (166), Expect = 1e-11 Identities = 48/145 (33%), Positives = 67/145 (46%), Gaps = 5/145 (3%) Frame = +2 Query: 188 IPNVRWFGVEGDYNVLVMDLLG-----PSLEDLFNFCSRKLSLKTVLMLADQMINRVEFV 352 IP++ G DY V+ LG E +F C MIN +EF+ Sbjct: 84 IPDLYGIGETDDYMFFVIKNLGRVFAPKDTESVFEACVT-------------MINTLEFI 130 Query: 353 HSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARY 532 HS+ F H I+P N L+ R ++ +ID+ K S + HI Y E+ +G Y Sbjct: 131 HSQGFTHGKIEPRNILI----RNKRLSLIDYSRTNKLYK-SGNSHIDYNEDMITSGNINY 185 Query: 533 ASVNTHLGIEQSRRDDLESLGYVLM 607 V+ HLG SRR DLE LGY ++ Sbjct: 186 MCVDNHLGATVSRRGDLEMLGYCMI 210
>KRB2_VACCA (O57259) Probable serine/threonine-protein kinase B12 (EC 2.7.11.1)| Length = 283 Score = 67.8 bits (164), Expect = 2e-11 Identities = 47/145 (32%), Positives = 67/145 (46%), Gaps = 5/145 (3%) Frame = +2 Query: 188 IPNVRWFGVEGDYNVLVMDLLG-----PSLEDLFNFCSRKLSLKTVLMLADQMINRVEFV 352 IP++ G DY V+ LG E +F C MIN +EF+ Sbjct: 84 IPDLYGIGETDDYMFFVIKNLGRVFAPKDTESVFEACVT-------------MINTLEFI 130 Query: 353 HSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARY 532 HS+ F H I+P N L+ R ++ +ID+ K S + HI Y E+ +G Y Sbjct: 131 HSRGFTHGKIEPRNILI----RNKRLSLIDYSRTNKLYK-SGNSHIDYNEDMITSGNINY 185 Query: 533 ASVNTHLGIEQSRRDDLESLGYVLM 607 V+ HLG S+R DLE LGY ++ Sbjct: 186 MCVDNHLGATVSKRGDLEMLGYCMI 210
>VRK3_HUMAN (Q8IV63) Serine/threonine-protein kinase VRK3 (EC 2.7.11.1)| (Vaccinia-related kinase 3) Length = 474 Score = 67.0 bits (162), Expect = 4e-11 Identities = 44/144 (30%), Positives = 76/144 (52%), Gaps = 4/144 (2%) Frame = +2 Query: 188 IPNVRWFGVEGD-YNVLVMDLLGPSLEDLFNFCSRK-LSLKTVLMLADQMINRVEFVHSK 361 IP FGV D Y LV+ LG SL+ + + LS ++VL +A ++++ +EF+H Sbjct: 241 IPTCMGFGVHQDKYRFLVLPSLGRSLQSALDVSPKHVLSERSVLQVACRLLDALEFLHEN 300 Query: 362 SFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLT--GTARYA 535 ++H ++ +N + +QV + +G A +Y + +H+ Y E G + Sbjct: 301 EYVHGNVTAENIFVD-PEDQSQVTLAGYGFAFRYCPSG--KHVAYVEGSRSPHEGDLEFI 357 Query: 536 SVNTHLGIEQSRRDDLESLGYVLM 607 S++ H G SRR DL+SLGY ++ Sbjct: 358 SMDLHKGCGPSRRSDLQSLGYCML 381
>PKND_CHLTR (O84303) Serine/threonine-protein kinase pknD (EC 2.7.11.1)| Length = 934 Score = 63.9 bits (154), Expect = 4e-10 Identities = 51/179 (28%), Positives = 86/179 (48%), Gaps = 21/179 (11%) Frame = +2 Query: 131 HPQLLYESKIYRILQGGTGI----PNVRWFGVEGDY-NVLVMDLLGPSLEDLFNFCSRKL 295 HP ++ +Y I G + P + F ++ +V ++L LE+ K Sbjct: 61 HPGIV---PVYSICSDGEAVYYTMPYIEGFSLKSLLKSVWQKEVLSKELEE-------KT 110 Query: 296 SLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLA--KKYRD 469 S+K+ L + D++ VE++HSK LHRD+KPDN L+GL +V +ID+G A K ++ Sbjct: 111 SVKSFLPIFDKICATVEYIHSKGVLHRDLKPDNILLGL---FGEVVIIDWGAAIFKHAKE 167 Query: 470 TSTHQH----IPYRENK----------NLTGTARYASVNTHLGIEQSRRDDLESLGYVL 604 Q + + E + GT Y + + LG+E S + D+ +LG +L Sbjct: 168 LKLEQDDEAAVSFDERNICYSSMTIPGKIVGTPDYMAPESLLGVEASEKTDIYALGLIL 226
>PKND_CHLMU (Q9PK92) Serine/threonine-protein kinase pknD (EC 2.7.11.1)| Length = 934 Score = 62.4 bits (150), Expect = 1e-09 Identities = 39/121 (32%), Positives = 61/121 (50%), Gaps = 16/121 (13%) Frame = +2 Query: 290 KLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGL-----A 454 K S+K L + D++ VE++HSK LHRD+KPDN L+GL +V ++D+G A Sbjct: 109 KTSVKAFLPIFDKICATVEYIHSKGVLHRDLKPDNILLGL---FGEVVIVDWGAAIFKHA 165 Query: 455 KKYRDTSTHQHIPYRENKN-----------LTGTARYASVNTHLGIEQSRRDDLESLGYV 601 K+ + + KN + GT Y + + LG E S + D+ +LG + Sbjct: 166 KELQQEKDEEGFSSYGQKNICYSSMTVPGKIVGTPDYMAPESLLGAEASEKTDIYALGLI 225 Query: 602 L 604 L Sbjct: 226 L 226
>V226_FOWPV (Q9J509) Probable serine/threonine-protein kinase FPV226 (EC| 2.7.11.1) Length = 292 Score = 62.0 bits (149), Expect = 1e-09 Identities = 40/129 (31%), Positives = 68/129 (52%), Gaps = 1/129 (0%) Frame = +2 Query: 224 YNVLVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLM 403 Y ++++ L + ++L + L +M M+ +E++H H DIKP+N ++ Sbjct: 98 YRFILLERLVENTKELLKRVKKPKPLIKNIM--KDMLYTLEYIHEHGISHGDIKPENIMV 155 Query: 404 GLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNL-TGTARYASVNTHLGIEQSRRDD 580 R+ Y+ID+G+ + H Y+E+KN GT YAS++ H G +RR D Sbjct: 156 DGRYRS---YLIDYGIVSYFIVNGKHVKY-YKESKNWHRGTLYYASLDAHNGTCVTRRGD 211 Query: 581 LESLGYVLM 607 LESLGY ++ Sbjct: 212 LESLGYCML 220
>VRK3_MOUSE (Q8K3G5) Serine/threonine-protein kinase VRK3 (EC 2.7.11.1)| (Vaccinia-related kinase 3) Length = 453 Score = 60.8 bits (146), Expect = 3e-09 Identities = 40/144 (27%), Positives = 74/144 (51%), Gaps = 4/144 (2%) Frame = +2 Query: 188 IPNVRWFGVEGD-YNVLVMDLLGPSLEDLFNFCSRKL-SLKTVLMLADQMINRVEFVHSK 361 IP FG+ D Y LV LG SL+ + + + S + VL +A ++++ +E++H Sbjct: 220 IPTCIGFGIHQDKYRFLVFPSLGRSLQSALDDNPKHVVSERCVLQVACRLLDALEYLHEN 279 Query: 362 SFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLT--GTARYA 535 ++H ++ +N + +QV ++ +G YR +H+ Y+E G + Sbjct: 280 EYVHGNLTAENVFVN-PEDLSQVTLVGYGFT--YRYCPGGKHVAYKEGSRSPHDGDLEFI 336 Query: 536 SVNTHLGIEQSRRDDLESLGYVLM 607 S++ H G SRR DL++LGY ++ Sbjct: 337 SMDLHKGCGPSRRSDLQTLGYCML 360
>PKN2_MYXXA (P54736) Serine/threonine-protein kinase pkn2 (EC 2.7.11.1)| Length = 830 Score = 60.1 bits (144), Expect = 5e-09 Identities = 51/189 (26%), Positives = 82/189 (43%), Gaps = 5/189 (2%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYE--SKIYRILQG--GTGIPNVRWFGVEGDY 226 E+YLG + +V IK+ + + E + R+L + + FG GD+ Sbjct: 26 EVYLGEQVSLGRKVAIKVLHHDLHAQAGMAERFKREARLLSAVEHPAVVRIVDFGESGDH 85 Query: 227 NVLVMDLL-GPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLM 403 LVM+ + G SL D+ + L L Q+ + +H K +HRD+KP+N + Sbjct: 86 ACLVMEFVEGESLYDVLT--PGPMPPGRALPLLQQLAEGLAAIHDKGIIHRDLKPENVFI 143 Query: 404 GLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDL 583 R Q ++DFG+A+ + + + GT Y S +G + R DL Sbjct: 144 SKSARGEQARLLDFGIARLVEPDAASS---VSQIGVVLGTPEYLSPEQAVGAKVDTRSDL 200 Query: 584 ESLGYVLMY 610 S G VL Y Sbjct: 201 YSFG-VLTY 208
>PKN2_CLOPE (Q8XJL8) Probable serine/threonine protein kinase CPE1738 (EC| 2.7.11.1) Length = 685 Score = 58.2 bits (139), Expect = 2e-08 Identities = 44/140 (31%), Positives = 66/140 (47%), Gaps = 1/140 (0%) Frame = +2 Query: 188 IPNVRWFGVEGDYNVLVMDLL-GPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKS 364 + NV G + D N +VM+ + G +L+D+ L + + + ++ +E H Sbjct: 70 VVNVLDVGTQDDINYIVMEYVEGKTLKDIIKE-KGALPYEVAISIGIKVAKALECAHKSG 128 Query: 365 FLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVN 544 +HRD+KP N L+ V V DFG+AK D+ST H ++ G+A Y S Sbjct: 129 IIHRDVKPQNILV---TEEGVVKVTDFGIAKS-MDSSTIAH-----TNSVMGSAHYFSPE 179 Query: 545 THLGIEQSRRDDLESLGYVL 604 G R DL SLG VL Sbjct: 180 QAKGTYTDYRTDLYSLGIVL 199
>PKN1_MYXXA (P33973) Serine/threonine-protein kinase pkn1 (EC 2.7.11.1)| Length = 693 Score = 58.2 bits (139), Expect = 2e-08 Identities = 48/186 (25%), Positives = 86/186 (46%), Gaps = 6/186 (3%) Frame = +2 Query: 62 IYLGTNIQTNEEVGIKLENVK-TKHPQLLY----ESKIYRILQGGTGIPNVRWFGVEGDY 226 +YLG ++ V +K+ + T +P+L+ E++ ++ G I ++ Sbjct: 73 VYLGEHVSIGSRVAVKVLHAHLTMYPELVQRFHAEARAVNLI-GHENIVSIFDMDATPPR 131 Query: 227 NVLVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDN-FLM 403 L+M+ L + L + L+ V+ + Q+ + ++ H++ +HRD+KPDN FL+ Sbjct: 132 PYLIMEFLDGA--PLSAWVGTPLAAGAVVSVLSQVCDALQAAHARGIVHRDLKPDNIFLV 189 Query: 404 GLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDL 583 A V V+DFG+AK H+P + GT Y + LG R DL Sbjct: 190 RRNGNAPFVKVLDFGIAK-----LADAHMPQTHAGIIVGTPEYMAPEQSLGRGVDGRADL 244 Query: 584 ESLGYV 601 +LG + Sbjct: 245 YALGVI 250
>PKN2_CLOAB (Q97IC2) Probable serine/threonine protein kinase CAC1728 (EC| 2.7.11.1) Length = 657 Score = 57.0 bits (136), Expect = 4e-08 Identities = 49/188 (26%), Positives = 85/188 (45%), Gaps = 7/188 (3%) Frame = +2 Query: 62 IYLGTNIQTNEEVGIK-LENVKTKHPQLLYESK-----IYRILQGGTGIPNVRWFGVEGD 223 +Y + N V +K L++ T+ + +++ K RI I N+ G +G+ Sbjct: 24 VYKAMDTLLNRHVAVKVLKHEFTEDEEFVFKFKREASAAARI--ANANIVNIYDVGADGN 81 Query: 224 YNVLVMDLL-GPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFL 400 N +VM+ + G +L+ L + K+ ++ A Q+ + F H +HRDIKP N + Sbjct: 82 VNYIVMEYVAGKTLKKLIKE-NGKIEFNKIIDYATQIAKALNFAHKNGIVHRDIKPHNIM 140 Query: 401 MGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDD 580 + + + V DFG+AK +++ + G+A Y S GI R D Sbjct: 141 V---TDDDIIKVTDFGIAKASNEST------ITTTNKVVGSAHYLSPEQAQGIPVDCRTD 191 Query: 581 LESLGYVL 604 + S G VL Sbjct: 192 IYSFGIVL 199
>PKN1_THETN (Q8R9T6) Probable serine/threonine-protein kinase Sps1 (EC| 2.7.11.1) Length = 625 Score = 57.0 bits (136), Expect = 4e-08 Identities = 43/133 (32%), Positives = 64/133 (48%), Gaps = 1/133 (0%) Frame = +2 Query: 209 GVEGDYNVLVMDLL-GPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIK 385 G EGD +VM+ + G +L++L L +K + +A Q+ ++ H +HRDIK Sbjct: 77 GQEGDIYYIVMEYVKGRTLKELIRENGGPLEVKRAVEIASQVCRALDHAHKNKIIHRDIK 136 Query: 386 PDNFLMGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQ 565 P N L+ + V V DFG+A+ + I Y ++ GTA Y S G Sbjct: 137 PQNILV---TDEDVVKVTDFGIARAANGAT----ITY--TGDVIGTAYYFSPEQAKGSIV 187 Query: 566 SRRDDLESLGYVL 604 R D+ SLG VL Sbjct: 188 DERTDIYSLGIVL 200
>PKNA_MYCTU (P65726) Probable serine/threonine-protein kinase pknA (EC| 2.7.11.1) Length = 431 Score = 55.8 bits (133), Expect = 1e-07 Identities = 46/145 (31%), Positives = 68/145 (46%), Gaps = 6/145 (4%) Frame = +2 Query: 185 GIPNVRWFGV-----EGDYNVLVMDLL-GPSLEDLFNFCSRKLSLKTVLMLADQMINRVE 346 GI +V +G EG LVM+L+ G L + R LSL+ L + +Q ++ Sbjct: 72 GIASVHDYGESQMNGEGRTAYLVMELVNGEPLNSVLKRTGR-LSLRHALDMLEQTGRALQ 130 Query: 347 FVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTA 526 H+ +HRD+KP N L+ QV + DFG+AK P + + GTA Sbjct: 131 IAHAAGLVHRDVKPGNILI---TPTGQVKITDFGIAKAV------DAAPVTQTGMVMGTA 181 Query: 527 RYASVNTHLGIEQSRRDDLESLGYV 601 +Y + LG + S D+ SLG V Sbjct: 182 QYIAPEQALGHDASPASDVYSLGVV 206
>PKNA_MYCBO (P65727) Probable serine/threonine-protein kinase pknA (EC| 2.7.11.1) Length = 431 Score = 55.8 bits (133), Expect = 1e-07 Identities = 46/145 (31%), Positives = 68/145 (46%), Gaps = 6/145 (4%) Frame = +2 Query: 185 GIPNVRWFGV-----EGDYNVLVMDLL-GPSLEDLFNFCSRKLSLKTVLMLADQMINRVE 346 GI +V +G EG LVM+L+ G L + R LSL+ L + +Q ++ Sbjct: 72 GIASVHDYGESQMNGEGRTAYLVMELVNGEPLNSVLKRTGR-LSLRHALDMLEQTGRALQ 130 Query: 347 FVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTA 526 H+ +HRD+KP N L+ QV + DFG+AK P + + GTA Sbjct: 131 IAHAAGLVHRDVKPGNILI---TPTGQVKITDFGIAKAV------DAAPVTQTGMVMGTA 181 Query: 527 RYASVNTHLGIEQSRRDDLESLGYV 601 +Y + LG + S D+ SLG V Sbjct: 182 QYIAPEQALGHDASPASDVYSLGVV 206
>PKNA_MYCLE (P54743) Probable serine/threonine-protein kinase pknA (EC| 2.7.11.1) Length = 437 Score = 54.3 bits (129), Expect(2) = 1e-07 Identities = 44/145 (30%), Positives = 68/145 (46%), Gaps = 6/145 (4%) Frame = +2 Query: 185 GIPNVRWFGV-----EGDYNVLVMDLL-GPSLEDLFNFCSRKLSLKTVLMLADQMINRVE 346 GI +V +G EG LVM+L+ G L + R LSL+ L + +Q ++ Sbjct: 72 GIASVHDYGESHMDGEGRTAYLVMELVNGEPLNSVLKRTGR-LSLRHALDMLEQTGRALQ 130 Query: 347 FVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTA 526 H+ +HRD+KP N L+ QV + DFG+AK P + + GTA Sbjct: 131 IAHAAGLVHRDVKPGNILI---TPTGQVKITDFGIAKAV------DAAPVTQTGMVMGTA 181 Query: 527 RYASVNTHLGIEQSRRDDLESLGYV 601 +Y + LG + + D+ SLG + Sbjct: 182 QYIAPEQALGHDATPASDVYSLGVI 206 Score = 20.8 bits (42), Expect(2) = 1e-07 Identities = 8/18 (44%), Positives = 12/18 (66%) Frame = +1 Query: 22 RLGRKXRQRFLRGDLSRD 75 RLGR+ + L+G+ S D Sbjct: 34 RLGRRVAVKVLKGEFSSD 51
>STE20_YEAST (Q03497) Serine/threonine-protein kinase STE20 (EC 2.7.11.1)| Length = 939 Score = 54.7 bits (130), Expect = 2e-07 Identities = 47/186 (25%), Positives = 88/186 (47%), Gaps = 4/186 (2%) Frame = +2 Query: 62 IYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWF----GVEGDYN 229 +Y I TN V IK N++ + + L ++I ++ G+ PN+ F ++GD Sbjct: 634 VYTAYEIGTNVSVAIKQMNLEKQPKKELIINEI--LVMKGSKHPNIVNFIDSYVLKGDLW 691 Query: 230 VLVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGL 409 V++ + G SL D+ C L+ + + + ++ +EF+HSK LHRDIK DN L+ + Sbjct: 692 VIMEYMEGGSLTDVVTHCI--LTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNILLSM 749 Query: 410 GRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLES 589 + + DFG + + + + + GT + + E + D+ S Sbjct: 750 ---EGDIKLTDFGFCAQINELNL-------KRTTMVGTPYWMAPEVVSRKEYGPKVDIWS 799 Query: 590 LGYVLM 607 LG +++ Sbjct: 800 LGIMII 805
>CSK2A_DICDI (Q02720) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II alpha| subunit) Length = 337 Score = 54.7 bits (130), Expect = 2e-07 Identities = 43/137 (31%), Positives = 73/137 (53%), Gaps = 2/137 (1%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIK-LENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVL 235 E++ G NI+ NE+ IK L+ VK K ++ E KI + L GG I + + V D Sbjct: 60 EVFEGANIKNNEKCVIKVLKPVKKK--KIKREIKILQNLCGGPNI--ITLYDVVRDPQSK 115 Query: 236 VMDLLGPSLEDL-FNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLG 412 L+ + + F S L+ V ++++ ++F HS +HRD+KP N ++ Sbjct: 116 TPSLIFEYINNTDFKHLSPTLTDFDVRYYIRELLHALDFCHSNGIMHRDVKPSNVMIDHQ 175 Query: 413 RRANQVYVIDFGLAKKY 463 +R ++Y+ID+GLA+ Y Sbjct: 176 KR--KLYLIDWGLAEFY 190
>PKND_CHLCV (Q822K5) Serine/threonine-protein kinase pknD (EC 2.7.11.1)| Length = 930 Score = 54.3 bits (129), Expect = 3e-07 Identities = 37/118 (31%), Positives = 62/118 (52%), Gaps = 11/118 (9%) Frame = +2 Query: 284 SRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFG--LAK 457 + + S+ T L + ++ + VE+VHS+ LHRD+KPDN L+GL ++V ++D+G L+K Sbjct: 107 AEQTSVATFLSIFHKICSTVEYVHSRGILHRDLKPDNILLGL---FSEVVILDWGAALSK 163 Query: 458 KYRD---TSTHQHIPYRENKNLT------GTARYASVNTHLGIEQSRRDDLESLGYVL 604 + + + IP N+T GT Y + G S D+ +LG +L Sbjct: 164 EMEEDFLSDIDVRIPGSLFSNMTIPGKIVGTPDYMAPERLRGTPASESTDIYALGVIL 221
>PKND_CHLPN (Q9Z986) Serine/threonine-protein kinase pknD (EC 2.7.11.1)| Length = 932 Score = 54.3 bits (129), Expect = 3e-07 Identities = 39/128 (30%), Positives = 60/128 (46%), Gaps = 14/128 (10%) Frame = +2 Query: 263 EDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVID 442 E L + K S+ L + ++ +E+VHS+ LHRD+KPDN L+GL ++ ++D Sbjct: 100 ESLSKELAEKTSVGAFLSIFHKICCTIEYVHSRGILHRDLKPDNILLGL---FSEAVILD 156 Query: 443 FGLA--------------KKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDD 580 +G A K S+ IP R + GT Y + LG S+ D Sbjct: 157 WGAAVACGEEEDLLDIDVSKEEVLSSRMTIPGR----IVGTPDYMAPERLLGHPASKSTD 212 Query: 581 LESLGYVL 604 + +LG VL Sbjct: 213 IYALGVVL 220
>PKNX_STRCO (Q9XA16) Probable serine/threonine-protein kinase SCO3848 (EC| 2.7.11.1) Length = 673 Score = 53.9 bits (128), Expect = 4e-07 Identities = 39/125 (31%), Positives = 64/125 (51%), Gaps = 1/125 (0%) Frame = +2 Query: 233 LVMDLL-GPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGL 409 +VM+ + G +L +L + RKL + L + ++ +E+ H +HRDIKP N ++ Sbjct: 90 IVMEYVDGSTLRELLH-SGRKLLPERTLEMTIGILQALEYSHRAGIVHRDIKPANVML-- 146 Query: 410 GRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLES 589 R QV V+DFG+A+ D+ + + + GTA+Y S G + R DL S Sbjct: 147 -TRNGQVKVMDFGIARAMGDSG----MTMTQTAAVIGTAQYLSPEQAKGEQVDARSDLYS 201 Query: 590 LGYVL 604 G +L Sbjct: 202 TGCLL 206
>PAK1_CAEEL (Q17850) Serine/threonine-protein kinase pak-1 (EC 2.7.11.1)| (p21-activated kinase 1) (PAK1) (CePAK) Length = 572 Score = 52.4 bits (124), Expect = 1e-06 Identities = 42/151 (27%), Positives = 72/151 (47%), Gaps = 6/151 (3%) Frame = +2 Query: 62 IYLGTNIQTNEEVGIKLENVKT--KHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVL 235 +Y I T EV IK N+K K ++ E + R + + + + V + V+ Sbjct: 309 VYTAIEISTEAEVAIKQMNLKDQPKKELIINEILVMRENKHANIVNYLDSYLVCDELWVV 368 Query: 236 VMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGR 415 + L G SL D+ C + + + + +++ +EF+HS+ +HRDIK DN L+G+ Sbjct: 369 MEYLAGGSLTDVVTECQMEDGI--IAAVCREVLQALEFLHSRHVIHRDIKSDNILLGMD- 425 Query: 416 RANQVYVIDFG----LAKKYRDTSTHQHIPY 496 V + DFG L+ + R +T PY Sbjct: 426 --GSVKLTDFGFCAQLSPEQRKRTTMVGTPY 454
>CDC2H_PLAFK (Q07785) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (PfPK5) Length = 288 Score = 52.4 bits (124), Expect = 1e-06 Identities = 33/108 (30%), Positives = 54/108 (50%), Gaps = 5/108 (4%) Frame = +2 Query: 230 VLVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGL 409 VLV + L L+ L + C L T Q++N + + H + LHRD+KP N L+ Sbjct: 76 VLVFEHLDQDLKKLLDVCEGGLESVTAKSFLLQLLNGIAYCHDRRVLHRDLKPQNLLI-- 133 Query: 410 GRRANQVYVIDFGLAKKYR---DTSTHQHIP--YRENKNLTGTARYAS 538 R ++ + DFGLA+ + TH+ + YR L G+ +Y++ Sbjct: 134 -NREGELKIADFGLARAFGIPVRKYTHEVVTLWYRAPDVLMGSKKYST 180
>CDC2H_PLAF7 (P61075) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 52.4 bits (124), Expect = 1e-06 Identities = 33/108 (30%), Positives = 54/108 (50%), Gaps = 5/108 (4%) Frame = +2 Query: 230 VLVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGL 409 VLV + L L+ L + C L T Q++N + + H + LHRD+KP N L+ Sbjct: 76 VLVFEHLDQDLKKLLDVCEGGLESVTAKSFLLQLLNGIAYCHDRRVLHRDLKPQNLLI-- 133 Query: 410 GRRANQVYVIDFGLAKKYR---DTSTHQHIP--YRENKNLTGTARYAS 538 R ++ + DFGLA+ + TH+ + YR L G+ +Y++ Sbjct: 134 -NREGELKIADFGLARAFGIPVRKYTHEVVTLWYRAPDVLMGSKKYST 180
>PIM1_BRARE (Q9YHZ5) Serine/threonine-protein kinase Pim-1 (EC 2.7.11.1)| Length = 310 Score = 52.0 bits (123), Expect = 1e-06 Identities = 38/118 (32%), Positives = 58/118 (49%), Gaps = 10/118 (8%) Frame = +2 Query: 149 ESKIYRILQGGTG-IPNVR-------WFGVEGDYNVLVMDLLGPSLEDLFNFCSRKLSLK 304 E + + L GG+G +P R WF + G ++V + +DLF+F + + L Sbjct: 82 EIALLQSLGGGSGSVPGHRGIIRMLDWFEIPGQEYLIVFEK-PQHCQDLFDFITERGRLD 140 Query: 305 TVLM--LADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYRDT 472 L Q+I V+F HSK +HRDIK +N L + R + VIDFG +D+ Sbjct: 141 ESLARRFLKQVIEAVQFCHSKGIVHRDIKDENIL--VDTRTGDIKVIDFGSGATLKDS 196
>ICL1_KLULA (Q6CWQ4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 361 Score = 52.0 bits (123), Expect = 1e-06 Identities = 34/95 (35%), Positives = 50/95 (52%) Frame = +2 Query: 326 QMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYREN 505 QM N ++++HSK+ LHRDIKP+N L+G N + + DFG + D ++ Sbjct: 206 QMANALDYMHSKNILHRDIKPENILIGFN---NTIKLTDFGWSVYNEDG--------QKR 254 Query: 506 KNLTGTARYASVNTHLGIEQSRRDDLESLGYVLMY 610 K L GT Y S E + + D+ +LG VL Y Sbjct: 255 KTLCGTIDYLSPELIKSREYNNKVDVWALG-VLTY 288
>ARK1_SCHPO (O59790) Serine/threonine-protein kinase ark1 (EC 2.7.11.1)| (Aurora-related kinase 1) Length = 355 Score = 51.6 bits (122), Expect = 2e-06 Identities = 48/173 (27%), Positives = 75/173 (43%), Gaps = 9/173 (5%) Frame = +2 Query: 119 VKTKHPQLLYESKIYRILQGGTGIPN-------VRWFGVEGDYNVLVMDLLGPSLEDLFN 277 +KT H L +SKI + ++ I + +R +G D + + L +L+ Sbjct: 117 LKTLHKSELVQSKIEKQVRREIEIQSNLRHKNILRLYGHFHDEKRIYLILEFAGRGELYQ 176 Query: 278 FCSR--KLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGL 451 R + S + QM N + ++H K +HRDIKP+N L+G+ ++ + DFG Sbjct: 177 HLRRAKRFSEEVASKYIFQMANALSYLHKKHVIHRDIKPENILLGID---GEIKLSDFGW 233 Query: 452 AKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGYVLMY 610 + H P L GT Y G E + + DL SLG VL Y Sbjct: 234 S---------VHAPSNRRTTLCGTLDYLPPEMVEGKEHTEKVDLWSLG-VLTY 276
>CDC2H_PLAYO (Q7RM49) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 289 Score = 51.6 bits (122), Expect = 2e-06 Identities = 32/108 (29%), Positives = 54/108 (50%), Gaps = 5/108 (4%) Frame = +2 Query: 230 VLVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGL 409 +LV + L L+ L + C L T Q++N + + H LHRD+KP N L+ Sbjct: 77 ILVFEHLDQDLKKLIDVCDGGLESVTAKSFLLQLLNGIAYCHEHRVLHRDLKPQNLLI-- 134 Query: 410 GRRANQVYVIDFGLAKKYRDTS---THQHIP--YRENKNLTGTARYAS 538 R ++ + DFGLA+ + + TH+ + YR L G+ +Y++ Sbjct: 135 -NREGELKIADFGLARAFGIPARRYTHEVVTLWYRAPDILMGSKKYST 181
>CDC7_MOUSE (Q9Z0H0) Cell division cycle 7-related protein kinase (EC 2.7.11.1)| (CDC7-related kinase) (muCdc7) Length = 564 Score = 51.6 bits (122), Expect = 2e-06 Identities = 41/141 (29%), Positives = 69/141 (48%), Gaps = 4/141 (2%) Frame = +2 Query: 62 IYLGT-NIQTNEEVGIKLEN-VKTKHP-QLLYESKIYRILQGGTGIPNVRWFGVEGDYNV 232 +YL T +Q E I L++ + T HP ++ E + + G + +++ + D+ V Sbjct: 66 VYLATAQLQEGHEEKIALKHLIPTSHPMRIAAELQCLTVAGGQDNVMGLKYCFRKNDHVV 125 Query: 233 LVMDLLG-PSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGL 409 + M L S D+ N LS + V + ++ +H +HRD+KP NFL Sbjct: 126 IAMPYLEHESFLDILN----SLSFQEVREYMYNLFVALKRIHQFGIVHRDVKPSNFL--Y 179 Query: 410 GRRANQVYVIDFGLAKKYRDT 472 RR + ++DFGLA+ RDT Sbjct: 180 NRRLKKYALVDFGLAQGTRDT 200
>CDC2H_PLACH (Q4Y4B1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 51.6 bits (122), Expect = 2e-06 Identities = 32/108 (29%), Positives = 54/108 (50%), Gaps = 5/108 (4%) Frame = +2 Query: 230 VLVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGL 409 +LV + L L+ L + C L T Q++N + + H LHRD+KP N L+ Sbjct: 76 ILVFEHLDQDLKKLIDVCDGGLESVTAKSFLLQLLNGIAYCHEHRVLHRDLKPQNLLI-- 133 Query: 410 GRRANQVYVIDFGLAKKYRDTS---THQHIP--YRENKNLTGTARYAS 538 R ++ + DFGLA+ + + TH+ + YR L G+ +Y++ Sbjct: 134 -NREGELKIADFGLARAFGIPARRYTHEVVTLWYRAPDILMGSKKYST 180
>CDC2H_PLABA (Q4Z6R1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 51.6 bits (122), Expect = 2e-06 Identities = 32/108 (29%), Positives = 54/108 (50%), Gaps = 5/108 (4%) Frame = +2 Query: 230 VLVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGL 409 +LV + L L+ L + C L T Q++N + + H LHRD+KP N L+ Sbjct: 76 ILVFEHLDQDLKKLIDVCDGGLESVTAKSFLLQLLNGIAYCHEHRVLHRDLKPQNLLI-- 133 Query: 410 GRRANQVYVIDFGLAKKYRDTS---THQHIP--YRENKNLTGTARYAS 538 R ++ + DFGLA+ + + TH+ + YR L G+ +Y++ Sbjct: 134 -NREGELKIADFGLARAFGIPARRYTHEVVTLWYRAPDILMGSKKYST 180
>CDC7_HUMAN (O00311) Cell division cycle 7-related protein kinase (EC 2.7.11.1)| (CDC7-related kinase) (HsCdc7) (huCdc7) Length = 574 Score = 51.6 bits (122), Expect = 2e-06 Identities = 41/141 (29%), Positives = 68/141 (48%), Gaps = 4/141 (2%) Frame = +2 Query: 62 IYLGT-NIQTNEEVGIKLEN-VKTKHP-QLLYESKIYRILQGGTGIPNVRWFGVEGDYNV 232 +YL T +Q E I L++ + T HP ++ E + + G + V++ + D+ V Sbjct: 72 VYLATAQLQVGPEEKIALKHLIPTSHPIRIAAELQCLTVAGGQDNVMGVKYCFRKNDHVV 131 Query: 233 LVMDLLG-PSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGL 409 + M L S D+ N LS + V + ++ +H +HRD+KP NFL Sbjct: 132 IAMPYLEHESFLDILN----SLSFQEVREYMLNLFKALKRIHQFGIVHRDVKPSNFL--Y 185 Query: 410 GRRANQVYVIDFGLAKKYRDT 472 RR + ++DFGLA+ DT Sbjct: 186 NRRLKKYALVDFGLAQGTHDT 206
>YP62_CAEEL (Q09437) Putative serine/threonine-protein kinase B0495.2 (EC| 2.7.11.1) Length = 719 Score = 51.2 bits (121), Expect = 2e-06 Identities = 49/174 (28%), Positives = 82/174 (47%), Gaps = 15/174 (8%) Frame = +2 Query: 62 IYLGTNIQTNEEVGIK---LENVKTKHPQLLYESKIYRILQGGT--GIPNVR--WFGVEG 220 +Y G + +T+E V +K +E K P + +I +L+ G I NV+ G Sbjct: 370 VYRGKDKRTDEIVALKRLKMEKEKEGFP-ITALREINMLLKAGNHPNIVNVKEILLGSNM 428 Query: 221 DYNVLVMDLLGPSLEDLFNFCSRK---LSLKTVLMLADQMINRVEFVHSKSFLHRDIKPD 391 D + M+ + ++ L + SR+ S+ L Q+++ +E +H LHRD+K Sbjct: 429 DKIYMAMEFVEHDMKSLLDTMSRRNKRFSIGEQKTLLQQLLSGIEHMHKLWILHRDLKTS 488 Query: 392 NFLMGLGRRANQVYVIDFGLAKKYRD-----TSTHQHIPYRENKNLTGTARYAS 538 N LM + + DFGLA++Y D TS + YR + L GT Y++ Sbjct: 489 NLLMS---HKGILKIADFGLAREYGDPLKKFTSIVVTLWYRSPELLLGTRLYST 539
>PKN5_MYXXA (P54737) Serine/threonine-protein kinase pkn5 (EC 2.7.11.1)| Length = 380 Score = 51.2 bits (121), Expect = 2e-06 Identities = 33/93 (35%), Positives = 46/93 (49%) Frame = +2 Query: 326 QMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYREN 505 Q+ + ++H +HRD+KP N ++ R QV ++DFGLAK D + E Sbjct: 227 QICEALAYIHGHGLVHRDLKPSNIMVDDDR---QVRLMDFGLAKFLADDAA-----ITEA 278 Query: 506 KNLTGTARYASVNTHLGIEQSRRDDLESLGYVL 604 L GT RY + LG R DL SLG +L Sbjct: 279 GKLVGTYRYMAPEQILGEPLDGRADLYSLGVIL 311
>CDC2H_DICDI (P34117) CDC2-like serine/threonine-protein kinase CRP (EC| 2.7.11.22) (EC 2.7.11.23) Length = 292 Score = 50.8 bits (120), Expect = 3e-06 Identities = 32/107 (29%), Positives = 53/107 (49%), Gaps = 5/107 (4%) Frame = +2 Query: 233 LVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLG 412 LV + L L+ + C ++S T+ Q++ V F H LHRD+KP N L+ Sbjct: 78 LVFEYLDQDLKKYLDECGGEISKPTIKSFMYQLLKGVAFCHDHRVLHRDLKPQNLLI--- 134 Query: 413 RRANQVYVIDFGLAKKYR-DTSTHQH----IPYRENKNLTGTARYAS 538 R ++ + DFGLA+ + T+ H + YR L G+ +Y++ Sbjct: 135 NRKGELKLADFGLARAFGIPVRTYSHEVVTLWYRAPDVLMGSRKYST 181
>MPH1_SCHPO (O94235) Serine/threonine-protein kinase mph1 (EC 2.7.12.2)| Length = 678 Score = 50.8 bits (120), Expect = 3e-06 Identities = 34/113 (30%), Positives = 59/113 (52%), Gaps = 7/113 (6%) Frame = +2 Query: 287 RKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYR 466 + ++L + M +QM+ V+ VH ++ +H D+KP NFL+ G + +IDFG+AK Sbjct: 412 KPINLNFIRMYWEQMLEAVQVVHDQNIVHSDLKPANFLLVEG----NLKLIDFGIAKAIG 467 Query: 467 DTSTHQH-------IPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGYVL 604 + +T+ H I Y + LT + + L ++ R D+ SLG +L Sbjct: 468 NDTTNIHRDSHIGTINYMAPEALTDMNAHTNSGVKL-VKLGRPSDVWSLGCIL 519
>KCC2_YEAST (P22517) Calcium/calmodulin-dependent protein kinase II (EC| 2.7.11.17) Length = 447 Score = 50.4 bits (119), Expect = 4e-06 Identities = 37/135 (27%), Positives = 65/135 (48%), Gaps = 6/135 (4%) Frame = +2 Query: 80 IQTNEEVGIKLENVKTKHP-----QLLYES-KIYRILQGGTGIPNVRWFGVEGDYNVLVM 241 + TNE+V IK+ K Q+LYE I + L + WF + + ++ Sbjct: 67 LSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLSHPNIVSFKDWFESKDKFYIVTQ 126 Query: 242 DLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRA 421 G L D + + V ++ Q++ VE++HSK+ +HRD+KP+N L Sbjct: 127 LATGGELFDRILSRGKFTEVDAVEIIV-QILGAVEYMHSKNVVHRDLKPENVLYVDKSEN 185 Query: 422 NQVYVIDFGLAKKYR 466 + + + DFG+AK+ + Sbjct: 186 SPLVIADFGIAKQLK 200
>PKNB_MYCLE (P54744) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 622 Score = 50.4 bits (119), Expect = 4e-06 Identities = 37/130 (28%), Positives = 62/130 (47%), Gaps = 1/130 (0%) Frame = +2 Query: 218 GDYNVLVMDLL-GPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDN 394 G +VM+ + G +L D+ + + + ++AD + F H +HRD+KP N Sbjct: 85 GPLPYIVMEYVDGATLRDIVHTDGPMPPQQAIEIVADAC-QALNFSHQNGIIHRDVKPAN 143 Query: 395 FLMGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRR 574 ++ N V V+DFG+A+ D+++ + + GTA+Y S G R Sbjct: 144 IMIS---ATNAVKVMDFGIARAIADSTS-----VTQTAAVIGTAQYLSPEQARGDSVDAR 195 Query: 575 DDLESLGYVL 604 D+ SLG VL Sbjct: 196 SDVYSLGCVL 205
>PKN2_BACSU (O34507) Probable serine/threonine-protein kinase yloP (EC| 2.7.11.1) Length = 648 Score = 50.4 bits (119), Expect = 4e-06 Identities = 48/188 (25%), Positives = 83/188 (44%), Gaps = 7/188 (3%) Frame = +2 Query: 62 IYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGI--PNVRWF---GVEGDY 226 +YL +I + EV IK+ + + R Q + + PN+ G E D Sbjct: 25 VYLAEDIILDREVAIKILRFDYANDNEFIR-RFRREAQSASSLDHPNIVSIYDLGEEDDI 83 Query: 227 NVLVMDLL-GPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLM 403 +VM+ + G +L++ + L K L + +Q+++ + H +HRDIKP N L+ Sbjct: 84 YYIVMEYVEGMTLKEYIT-ANGPLHPKEALNIMEQIVSAIAHAHQNQIVHRDIKPHNILI 142 Query: 404 GLGRRANQVYVIDFGLAKKYRDTS-THQHIPYRENKNLTGTARYASVNTHLGIEQSRRDD 580 + V DFG+A T+ TH ++ G+ Y S G +++ D Sbjct: 143 D---HMGNIKVTDFGIATALSSTTITH-------TNSVLGSVHYLSPEQARGGLATKKSD 192 Query: 581 LESLGYVL 604 + +LG VL Sbjct: 193 IYALGIVL 200
>PKNB_MYCTU (P0A5S4) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 626 Score = 50.4 bits (119), Expect = 4e-06 Identities = 37/130 (28%), Positives = 60/130 (46%), Gaps = 1/130 (0%) Frame = +2 Query: 218 GDYNVLVMDLL-GPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDN 394 G +VM+ + G +L D+ + + + ++AD + F H +HRD+KP N Sbjct: 85 GPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIADAC-QALNFSHQNGIIHRDVKPAN 143 Query: 395 FLMGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRR 574 ++ N V V+DFG+A+ D+ + + GTA+Y S G R Sbjct: 144 IMIS---ATNAVKVMDFGIARAIADSGN----SVTQTAAVIGTAQYLSPEQARGDSVDAR 196 Query: 575 DDLESLGYVL 604 D+ SLG VL Sbjct: 197 SDVYSLGCVL 206
>PKNB_MYCBO (P0A5S5) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 626 Score = 50.4 bits (119), Expect = 4e-06 Identities = 37/130 (28%), Positives = 60/130 (46%), Gaps = 1/130 (0%) Frame = +2 Query: 218 GDYNVLVMDLL-GPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDN 394 G +VM+ + G +L D+ + + + ++AD + F H +HRD+KP N Sbjct: 85 GPLPYIVMEYVDGVTLRDIVHTEGPMTPKRAIEVIADAC-QALNFSHQNGIIHRDVKPAN 143 Query: 395 FLMGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRR 574 ++ N V V+DFG+A+ D+ + + GTA+Y S G R Sbjct: 144 IMIS---ATNAVKVMDFGIARAIADSGN----SVTQTAAVIGTAQYLSPEQARGDSVDAR 196 Query: 575 DDLESLGYVL 604 D+ SLG VL Sbjct: 197 SDVYSLGCVL 206
>CDC2B_ANTMA (Q38773) Cell division control protein 2 homolog B (EC 2.7.11.22)| (EC 2.7.11.23) (Fragment) Length = 280 Score = 50.1 bits (118), Expect = 5e-06 Identities = 46/168 (27%), Positives = 73/168 (43%), Gaps = 9/168 (5%) Frame = +2 Query: 62 IYLGTNIQTNEEVGIK---LENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNV 232 +Y +I+TNE++ +K LE P I N++ Sbjct: 5 VYKARDIETNEDIALKKIRLEQEDEGVPSTAIREISLLKEMHHENIVNLKDVVHREKRLY 64 Query: 233 LVMDLLGPSLEDLFNFCSR-KLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGL 409 LV + L L+ + C L V M Q++ V + HS LHRD+KP N L + Sbjct: 65 LVFEYLDLDLKKHMDSCPEFSQDLHMVKMFLCQILRGVAYCHSHRVLHRDLKPQNLL--I 122 Query: 410 GRRANQVYVIDFGLAKKYR---DTSTHQHIP--YRENKNLTGTARYAS 538 R +N + + DFGLA+ + T TH+ + YR + L G+ Y++ Sbjct: 123 DRGSNTIKLADFGLARAFGIPVRTFTHEVVTLWYRAPEVLLGSRHYST 170
>CSK23_ARATH (O64817) Probable casein kinase II subunit alpha (EC 2.7.11.1) (CK| II) Length = 333 Score = 49.7 bits (117), Expect = 7e-06 Identities = 39/137 (28%), Positives = 71/137 (51%), Gaps = 2/137 (1%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIK-LENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVL 235 E++ G N+ TNE IK L+ VK K ++ E KI + L GG I V+ + + D + Sbjct: 47 EVFEGKNVNTNERCVIKILKPVKKK--KIKREIKILQNLCGGPNI--VKLYDIVRDEHSK 102 Query: 236 VMDLLGPSLEDL-FNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLG 412 L+ + + F L+ + +++ ++F HS+ +HRD+KP N + + Sbjct: 103 TPSLVFEFVNSVDFKVLYPTLTDYDIRYYIYELLKALDFCHSQGIMHRDVKPHNVM--ID 160 Query: 413 RRANQVYVIDFGLAKKY 463 + ++ +ID+GLA+ Y Sbjct: 161 HQLRKLRLIDWGLAEFY 177
>MKK1_YEAST (P32490) MAP kinase kinase MKK1/SSP32 (EC 2.7.12.2)| Length = 508 Score = 49.7 bits (117), Expect = 7e-06 Identities = 46/179 (25%), Positives = 85/179 (47%), Gaps = 11/179 (6%) Frame = +2 Query: 104 IKLENVKTKHPQLLYESKIYRILQGGTGIPN---VRWFGV----EGDYNVLVMDLLGP-S 259 +K+ N P+ Y+ +I+R LQ + VR++G+ E + M+ +G S Sbjct: 249 LKVINTLNTDPE--YQKQIFRELQFNRSFQSEYIVRYYGMFTDDENSSIYIAMEYMGGRS 306 Query: 260 LEDLF-NFCSR--KLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQV 430 L+ ++ N R ++S K + +A+ ++ + ++H K +HRDIKP N L+ QV Sbjct: 307 LDAIYKNLLERGGRISEKVLGKIAEAVLRGLSYLHEKKVIHRDIKPQNILL---NENGQV 363 Query: 431 YVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGYVLM 607 + DFG++ + ++ TGT+ Y + G S D+ SLG ++ Sbjct: 364 KLCDFGVSGEAVNSLA---------TTFTGTSFYMAPERIQGQPYSVTSDVWSLGLTIL 413
>CDK5_RAT (Q03114) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) Length = 292 Score = 49.7 bits (117), Expect = 7e-06 Identities = 26/77 (33%), Positives = 43/77 (55%) Frame = +2 Query: 233 LVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLG 412 LV + L+ F+ C+ L + V L Q++ + F HS++ LHRD+KP N L+ Sbjct: 78 LVFEFCDQDLKKYFDSCNGDLDPEIVKSLLFQLLKGLGFCHSRNVLHRDLKPQNLLI--- 134 Query: 413 RRANQVYVIDFGLAKKY 463 R ++ + DFGLA+ + Sbjct: 135 NRNGELKLADFGLARAF 151
>PKNB_BIFLO (Q8G6P9) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 690 Score = 49.7 bits (117), Expect = 7e-06 Identities = 36/125 (28%), Positives = 62/125 (49%), Gaps = 1/125 (0%) Frame = +2 Query: 233 LVMDLL-GPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGL 409 +VM+ + G +L D+ + LS + + ++N +++ H +HRDIKP N ++ Sbjct: 98 IVMEYVKGQTLRDIIKV-NGALSQRDCEQVMLGVLNALDYSHRMGIIHRDIKPGNIMIS- 155 Query: 410 GRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLES 589 V V+DFG+A+ D++ +++ + GTA+Y S G R DL S Sbjct: 156 --EQGVVKVMDFGIARALDDSAA----TMTQSQGVVGTAQYLSPEQARGETVDMRSDLYS 209 Query: 590 LGYVL 604 G VL Sbjct: 210 AGCVL 214
>KC47_ORYSA (P29620) CDC2+/CDC28-related protein kinase R2 (EC 2.7.11.22)| Length = 424 Score = 49.3 bits (116), Expect = 9e-06 Identities = 42/137 (30%), Positives = 64/137 (46%), Gaps = 5/137 (3%) Frame = +2 Query: 143 LYESKIYRILQGGTGIPNVRWFGVEGDYNVLVMDLLGPSLEDLFNFCSRKLSLKTVLMLA 322 L E K+ + L+ I + F +G+ + LV + + LE + + LS Sbjct: 64 LREIKLLKELKDSNIIELIDAFPYKGNLH-LVFEFMETDLEAVIRDRNIVLSPADTKSYI 122 Query: 323 DQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYRDTS---THQHIP 493 M+ + F H K LHRD+KP+N L+G Q+ + DFGLA+ + THQ Sbjct: 123 QMMLKGLAFCHKKWVLHRDMKPNNLLIGAD---GQLKLADFGLARIFGSPERNFTHQVFA 179 Query: 494 --YRENKNLTGTARYAS 538 YR + L GT +Y S Sbjct: 180 RWYRAPELLFGTKQYGS 196
>CCRK_HUMAN (Q8IZL9) Cell cycle-related kinase (EC 2.7.11.22)| (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) Length = 346 Score = 49.3 bits (116), Expect = 9e-06 Identities = 41/167 (24%), Positives = 74/167 (44%), Gaps = 10/167 (5%) Frame = +2 Query: 62 IYLGTNIQTNEEVGIK---LENVKTKHP-QLLYESKIYRILQGGTGIPNVRWFGVEGDYN 229 ++ +++T E V +K L ++ P Q L E K + ++ + ++ G Sbjct: 18 VFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMEDNQYVVQLKAVFPHGGGF 77 Query: 230 VLVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGL 409 VL + + L ++ R L+ V ++ V F H+ + +HRD+KP N L+ Sbjct: 78 VLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHANNIVHRDLKPANLLIS- 136 Query: 410 GRRANQVYVIDFGLAKKYRDTS----THQHIP--YRENKNLTGTARY 532 + Q+ + DFGLA+ + THQ YR + L G +Y Sbjct: 137 --ASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGARQY 181
>CDC2H_PLAVI (Q9XZD6) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (Pvcrk2) Length = 288 Score = 48.9 bits (115), Expect = 1e-05 Identities = 31/108 (28%), Positives = 53/108 (49%), Gaps = 5/108 (4%) Frame = +2 Query: 230 VLVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGL 409 +LV + L L+ L + C L T Q+++ + + H LHRD+KP N L+ Sbjct: 76 ILVFEHLDQDLKKLLDVCDGGLESVTAKSFLLQLLSGIAYCHEHRVLHRDLKPQNLLI-- 133 Query: 410 GRRANQVYVIDFGLAKKYR---DTSTHQHIP--YRENKNLTGTARYAS 538 R ++ + DFGLA+ + TH+ + YR L G+ +Y++ Sbjct: 134 -NREGELKIADFGLARAFGIPVRKYTHEVVTLWYRAPDILMGSKKYST 180
>CDC2H_PLAKH (O96821) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 48.9 bits (115), Expect = 1e-05 Identities = 31/108 (28%), Positives = 53/108 (49%), Gaps = 5/108 (4%) Frame = +2 Query: 230 VLVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGL 409 +LV + L L+ L + C L T Q+++ + + H LHRD+KP N L+ Sbjct: 76 ILVFEHLDQDLKKLLDVCDGGLESVTAKSFLLQLLSGIAYCHEHRVLHRDLKPQNLLI-- 133 Query: 410 GRRANQVYVIDFGLAKKYR---DTSTHQHIP--YRENKNLTGTARYAS 538 R ++ + DFGLA+ + TH+ + YR L G+ +Y++ Sbjct: 134 -NREGELKIADFGLARAFGIPVRKYTHEVVTLWYRAPDILMGSKKYST 180
>CDC21_MEDSA (P24923) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (Fragment) Length = 291 Score = 48.9 bits (115), Expect = 1e-05 Identities = 30/84 (35%), Positives = 46/84 (54%), Gaps = 5/84 (5%) Frame = +2 Query: 302 KTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYR---DT 472 + V M QM+ + + HS LHRD+KP N L + RR N + + DFGLA+ + T Sbjct: 99 RQVKMFLYQMLCGIAYCHSHRVLHRDLKPQNLL--IDRRTNSLKLADFGLARAFGIPVRT 156 Query: 473 STHQHIP--YRENKNLTGTARYAS 538 TH+ + YR + L G+ Y++ Sbjct: 157 FTHEVVTLWYRAPEILLGSRHYST 180
>E2AK3_MOUSE (Q9Z2B5) Eukaryotic translation initiation factor 2-alpha kinase 3| precursor (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) Length = 1114 Score = 48.9 bits (115), Expect = 1e-05 Identities = 38/124 (30%), Positives = 56/124 (45%), Gaps = 10/124 (8%) Frame = +2 Query: 263 EDLFNFCSRKLSLK-----TVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQ 427 E+L ++ +R+ SL+ L + Q+ VEF+HSK +HRD+KP N + + Sbjct: 892 ENLKDWMNRRCSLEDREHGVCLHIFLQIAEAVEFLHSKGLMHRDLKPSNIFFTMD---DV 948 Query: 428 VYVIDFGLAKKYRDTSTHQHI-----PYRENKNLTGTARYASVNTHLGIEQSRRDDLESL 592 V V DFGL Q + Y + GT Y S G S + D+ SL Sbjct: 949 VKVGDFGLVTAMDQDEEEQTVLTPMPAYATHTGQVGTKLYMSPEQIHGNNYSHKVDIFSL 1008 Query: 593 GYVL 604 G +L Sbjct: 1009 GLIL 1012
>PCTK3_PONPY (Q5RD01) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 472 Score = 48.9 bits (115), Expect = 1e-05 Identities = 30/107 (28%), Positives = 53/107 (49%), Gaps = 5/107 (4%) Frame = +2 Query: 233 LVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLG 412 LV + L L+ + C +S+ V + Q++ + + H + LHRD+KP N L+ Sbjct: 215 LVFEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLLI--- 271 Query: 413 RRANQVYVIDFGLAK-KYRDTSTHQH----IPYRENKNLTGTARYAS 538 ++ + DFGLA+ K T T+ + + YR L G+ Y++ Sbjct: 272 NERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYST 318
>PCTK3_HUMAN (Q07002) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 472 Score = 48.9 bits (115), Expect = 1e-05 Identities = 30/107 (28%), Positives = 53/107 (49%), Gaps = 5/107 (4%) Frame = +2 Query: 233 LVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLG 412 LV + L L+ + C +S+ V + Q++ + + H + LHRD+KP N L+ Sbjct: 215 LVFEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLLI--- 271 Query: 413 RRANQVYVIDFGLAK-KYRDTSTHQH----IPYRENKNLTGTARYAS 538 ++ + DFGLA+ K T T+ + + YR L G+ Y++ Sbjct: 272 NERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYST 318
>KOK0_YEAST (Q12236) Probable serine/threonine-protein kinase YOL100W (EC| 2.7.11.1) Length = 1081 Score = 48.9 bits (115), Expect = 1e-05 Identities = 50/190 (26%), Positives = 81/190 (42%), Gaps = 9/190 (4%) Frame = +2 Query: 62 IYLGTNIQTNEEVGIKLENVK--TKHPQLLYESKIYRILQGGTGIPNV-RWFGVEGDYNV 232 + L T+I T + K+ N + + ++ Y S LQ P+V R F D + Sbjct: 193 VMLATSIDTKKRYAAKVLNKEYLIRQKKVKYVSIEKTALQKLNNSPSVVRLFSTFQDESS 252 Query: 233 LVMDLLGPSLEDLFNFCSRKLSLKTVLM--LADQMINRVEFVHSKSFLHRDIKPDNFLMG 406 L L D + + SL A Q+I+ ++++HS +HRDIKP+N L+ Sbjct: 253 LYFLLEYAPNGDFLSLMKKYGSLDETCARYYAAQIIDAIDYLHSNGIIHRDIKPENILLD 312 Query: 407 LGRRANQVYVIDFGLAKKYRDTSTHQHIPYRE----NKNLTGTARYASVNTHLGIEQSRR 574 ++ + DFG AK T+ P + +K+ GTA Y S R Sbjct: 313 ---GEMKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSPELLNDSFTDYR 369 Query: 575 DDLESLGYVL 604 D+ + G +L Sbjct: 370 CDIWAFGCIL 379
>YR436_MIMIV (Q7T6Y1) Putative serine/threonine-protein kinase R436 (EC| 2.7.11.1) Length = 276 Score = 48.5 bits (114), Expect = 2e-05 Identities = 51/202 (25%), Positives = 92/202 (45%), Gaps = 19/202 (9%) Frame = +2 Query: 62 IYLGTNIQTNEEVGIKLENVKTKHPQ-LLYESKIYRILQGGTGIPNVRWFGVEGDYNVLV 238 I++GT+ T ++V IK+ + K K + +L + I IL PN+ DY V Sbjct: 20 IFIGTDTITLQKVVIKIYDDKNKSKESILRDIHIPSILNH----PNIIKIK---DY---V 69 Query: 239 MDLLGPSLEDLFNFCSRKLSLKT----------------VLMLADQMINRVEFVHSKSFL 370 DL + ++ + +SL+ ++ + Q+++ + ++H + + Sbjct: 70 EDLDSNKMYVIYPYIDNTISLRNLPVDKFDVTDLFKLYYIIDILIQVVDAISYMHDNNIV 129 Query: 371 HRDIKPDNFLMGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTH 550 HRDIKPDN L+ ++V++IDF L+ D + P R K GT + + Sbjct: 130 HRDIKPDNILLN-----DKVHLIDFDLS----DQLDNPKFPVR--KGTIGTPNFMAPEIW 178 Query: 551 LGIEQ--SRRDDLESLGYVLMY 610 I Q ++ D+ SLG + Y Sbjct: 179 WKINQVDYKKTDIYSLGITMYY 200
>CDK5_XENLA (P51166) Cell division protein kinase 5 (EC 2.7.11.22) (Neuronal| cyclin-dependent kinase 5) Length = 292 Score = 48.5 bits (114), Expect = 2e-05 Identities = 25/77 (32%), Positives = 42/77 (54%) Frame = +2 Query: 233 LVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLG 412 LV + L+ F+ C+ L + V Q++ + F HS++ LHRD+KP N L+ Sbjct: 78 LVFEFCDQDLKKYFDSCNGDLDPEIVKSFMYQLLKGLAFCHSRNVLHRDLKPQNLLI--- 134 Query: 413 RRANQVYVIDFGLAKKY 463 R ++ + DFGLA+ + Sbjct: 135 NRNGELKLADFGLARAF 151
>CDC2_MAIZE (P23111) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 48.1 bits (113), Expect = 2e-05 Identities = 34/108 (31%), Positives = 55/108 (50%), Gaps = 6/108 (5%) Frame = +2 Query: 233 LVMDLLGPSLEDLFNFCSRKLSLKTVLM-LADQMINRVEFVHSKSFLHRDIKPDNFLMGL 409 LV + L L+ + C T++ Q+++ V + HS LHRD+KP N L + Sbjct: 78 LVFEYLDLDLKKFMDSCPEFAKNPTLIKSYLYQILHGVAYCHSHRVLHRDLKPQNLL--I 135 Query: 410 GRRANQVYVIDFGLAKKYR---DTSTHQHIP--YRENKNLTGTARYAS 538 RR N + + DFGLA+ + T TH+ + YR + L G +Y++ Sbjct: 136 DRRTNALKLADFGLARAFGIPVRTFTHEVVTLWYRAPEILLGARQYST 183
>CDC2A_ANTMA (Q38772) Cell division control protein 2 homolog A (EC 2.7.11.22)| (EC 2.7.11.23) Length = 294 Score = 48.1 bits (113), Expect = 2e-05 Identities = 29/84 (34%), Positives = 46/84 (54%), Gaps = 5/84 (5%) Frame = +2 Query: 302 KTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYR---DT 472 + V M Q++ + + HS LHRD+KP N L + RR N + + DFGLA+ + T Sbjct: 102 RLVKMFLYQILRGIAYCHSHRVLHRDLKPQNLL--IDRRTNALKLADFGLARAFGIPVRT 159 Query: 473 STHQHIP--YRENKNLTGTARYAS 538 TH+ + YR + L G+ Y++ Sbjct: 160 FTHEVVTLWYRAPEILLGSRHYST 183
>CDC21_ORYSA (P29618) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| Length = 294 Score = 48.1 bits (113), Expect = 2e-05 Identities = 34/108 (31%), Positives = 55/108 (50%), Gaps = 6/108 (5%) Frame = +2 Query: 233 LVMDLLGPSLEDLFNFCSRKLSLKTVLM-LADQMINRVEFVHSKSFLHRDIKPDNFLMGL 409 LV + L L+ + C T++ Q++ V + HS LHRD+KP N L + Sbjct: 78 LVFEYLDLDLKKFMDSCPEFAKNPTLIKSYLYQILRGVAYCHSHRVLHRDLKPQNLL--I 135 Query: 410 GRRANQVYVIDFGLAKKYR---DTSTHQHIP--YRENKNLTGTARYAS 538 RR N + + DFGLA+ + T TH+ + YR + L G+ +Y++ Sbjct: 136 DRRTNALKLADFGLARAFGIPVRTFTHEVVTLWYRAPEILLGSRQYST 183
>CDC7_YEAST (P06243) Cell division control protein 7 (EC 2.7.11.1)| Length = 507 Score = 48.1 bits (113), Expect = 2e-05 Identities = 24/61 (39%), Positives = 36/61 (59%) Frame = +2 Query: 287 RKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYR 466 R L +K + +++ ++FVHSK +HRDIKP NFL L + ++DFGLA+ Sbjct: 133 RDLPIKGIKKYIWELLRALKFVHSKGIIHRDIKPTNFLFNL--ELGRGVLVDFGLAEAQM 190 Query: 467 D 469 D Sbjct: 191 D 191
>CDK5_MOUSE (P49615) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) (CRK6) Length = 292 Score = 48.1 bits (113), Expect = 2e-05 Identities = 25/77 (32%), Positives = 42/77 (54%) Frame = +2 Query: 233 LVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLG 412 LV + L+ F+ C+ L + V Q++ + F HS++ LHRD+KP N L+ Sbjct: 78 LVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLI--- 134 Query: 413 RRANQVYVIDFGLAKKY 463 R ++ + DFGLA+ + Sbjct: 135 NRNGELKLADFGLARAF 151
>CDK5_HUMAN (Q00535) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) Length = 292 Score = 48.1 bits (113), Expect = 2e-05 Identities = 25/77 (32%), Positives = 42/77 (54%) Frame = +2 Query: 233 LVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLG 412 LV + L+ F+ C+ L + V Q++ + F HS++ LHRD+KP N L+ Sbjct: 78 LVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLI--- 134 Query: 413 RRANQVYVIDFGLAKKY 463 R ++ + DFGLA+ + Sbjct: 135 NRNGELKLADFGLARAF 151
>CDK5_BOVIN (Q02399) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Proline-directed protein kinase 33 kDa subunit) (PDPK) Length = 292 Score = 48.1 bits (113), Expect = 2e-05 Identities = 25/77 (32%), Positives = 42/77 (54%) Frame = +2 Query: 233 LVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLG 412 LV + L+ F+ C+ L + V Q++ + F HS++ LHRD+KP N L+ Sbjct: 78 LVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLI--- 134 Query: 413 RRANQVYVIDFGLAKKY 463 R ++ + DFGLA+ + Sbjct: 135 NRNGELKLADFGLARAF 151
>KPCD2_HUMAN (Q9BZL6) Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2)| Length = 878 Score = 48.1 bits (113), Expect = 2e-05 Identities = 50/189 (26%), Positives = 88/189 (46%), Gaps = 6/189 (3%) Frame = +2 Query: 62 IYLGTNIQTNEEVGIKLENVKTKHP-----QLLYESKIYRILQGGTGIPNVRWFGVEGDY 226 +Y G + +T +V +K+ + K + P QL E I + L+ GI N+ + Sbjct: 565 VYGGKHRKTGRDVAVKVID-KLRFPTKQESQLRNEVAILQSLRH-PGIVNLECMFETPEK 622 Query: 227 NVLVMDLL-GPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLM 403 +VM+ L G LE + + +L + L Q++ + +H K+ +H D+KP+N L+ Sbjct: 623 VFVVMEKLHGDMLEMILSSEKGRLPERLTKFLITQILVALRHLHFKNIVHCDLKPENVLL 682 Query: 404 GLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDL 583 QV + DFG A+ + S +++ GT Y + L +R D+ Sbjct: 683 ASADPFPQVKLCDFGFARIIGEKSF--------RRSVVGTPAYLAPEVLLNQGYNRSLDM 734 Query: 584 ESLGYVLMY 610 S+G V+MY Sbjct: 735 WSVG-VIMY 742
>ULK1_HUMAN (O75385) Serine/threonine-protein kinase ULK1 (EC 2.7.11.1)| (Unc-51-like kinase 1) Length = 1050 Score = 48.1 bits (113), Expect = 2e-05 Identities = 38/131 (29%), Positives = 59/131 (45%), Gaps = 7/131 (5%) Frame = +2 Query: 233 LVMDLL-GPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMG- 406 LVM+ G L D + R LS T+ + Q+ + +HSK +HRD+KP N L+ Sbjct: 90 LVMEYCNGGDLADYLH-AMRTLSEDTIRLFLQQIAGAMRLLHSKGIIHRDLKPQNILLSN 148 Query: 407 -LGRRAN----QVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSR 571 GRRAN +V + DFG A+ + L G+ Y + + Sbjct: 149 PAGRRANPNSIRVKIADFGFARYLQSNMM--------AATLCGSPMYMAPEVIMSQHYDG 200 Query: 572 RDDLESLGYVL 604 + DL S+G ++ Sbjct: 201 KADLWSIGTIV 211
>CSK2A_CAEEL (P18334) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II alpha| subunit) Length = 360 Score = 48.1 bits (113), Expect = 2e-05 Identities = 44/160 (27%), Positives = 80/160 (50%), Gaps = 2/160 (1%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIK-LENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVL 235 E++ G + T+E+V +K L+ VK K ++ E KI L+GGT I + V D Sbjct: 51 EVFEGFKMSTDEKVVVKILKPVKKK--KIKREIKILENLRGGTNI--ITLLDVVKDPISR 106 Query: 236 VMDLLGPSLEDL-FNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLG 412 L+ + + F + LS + +++ ++F HS+ +HRD+KP N ++ Sbjct: 107 TPALIFEHVNNSDFKQLYQTLSDYDIRYYLYELLKALDFCHSQGIMHRDVKPHNVMIDAE 166 Query: 413 RRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARY 532 +R ++ +ID+GLA+ Y R++ N+ +RY Sbjct: 167 KR--ELRLIDWGLAEFYHP---------RQDYNVRVASRY 195
>PCTK2_MOUSE (Q8K0D0) Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 2) Length = 523 Score = 47.8 bits (112), Expect = 3e-05 Identities = 30/107 (28%), Positives = 54/107 (50%), Gaps = 5/107 (4%) Frame = +2 Query: 233 LVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLG 412 LV + L L+ + C +S+ V + Q++ + + H + LHRD+KP N L+ Sbjct: 265 LVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLI--- 321 Query: 413 RRANQVYVIDFGLAK-KYRDTSTHQH----IPYRENKNLTGTARYAS 538 ++ + DFGLA+ K T T+ + + YR L G++ Y++ Sbjct: 322 NERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYST 368
>PCTK2_HUMAN (Q00537) Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 2) Length = 523 Score = 47.8 bits (112), Expect = 3e-05 Identities = 30/107 (28%), Positives = 54/107 (50%), Gaps = 5/107 (4%) Frame = +2 Query: 233 LVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLG 412 LV + L L+ + C +S+ V + Q++ + + H + LHRD+KP N L+ Sbjct: 265 LVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLI--- 321 Query: 413 RRANQVYVIDFGLAK-KYRDTSTHQH----IPYRENKNLTGTARYAS 538 ++ + DFGLA+ K T T+ + + YR L G++ Y++ Sbjct: 322 NEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYST 368
>PKN2_CORGL (Q8NU97) Serine/threonine protein kinases pknA (EC 2.7.11.1)| Length = 469 Score = 47.8 bits (112), Expect = 3e-05 Identities = 39/124 (31%), Positives = 56/124 (45%), Gaps = 1/124 (0%) Frame = +2 Query: 233 LVMDLL-GPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGL 409 +VM+ + G SL DL R L L + +Q + + +H +HRDIKP N L+ Sbjct: 100 IVMEFVRGESLADLLEREGR-LPEDLALDVMEQAAHGLSVIHRMDMVHRDIKPGNMLITA 158 Query: 410 GRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLES 589 V + DFG+AK +P + GTA+Y S G E + D+ S Sbjct: 159 N---GIVKITDFGIAK------AAAAVPLTRTGMVVGTAQYVSPEQAQGKEVTAASDIYS 209 Query: 590 LGYV 601 LG V Sbjct: 210 LGVV 213
>PKNB_LACLA (Q9CEF5) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 627 Score = 47.8 bits (112), Expect = 3e-05 Identities = 35/142 (24%), Positives = 67/142 (47%), Gaps = 4/142 (2%) Frame = +2 Query: 191 PNVRWFGVEGDYN---VLVMDLL-GPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHS 358 PN+ G++ +VM+ + G +L+ N + L+ + + ++++ ++ HS Sbjct: 71 PNIVGISDVGEFESQQYIVMEFVDGMTLKQYINQ-NAPLANDEAIEIITEILSAMDMAHS 129 Query: 359 KSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYAS 538 +HRD+KP N L+ + V V DFG+AK +TS Q + G+ Y S Sbjct: 130 HGIIHRDLKPQNVLVS---SSGTVKVTDFGIAKALSETSLTQ------TNTMFGSVHYLS 180 Query: 539 VNTHLGIEQSRRDDLESLGYVL 604 G + + D+ ++G +L Sbjct: 181 PEQARGSNATVQSDIYAIGIIL 202
>PCTK3_RAT (O35832) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 451 Score = 47.8 bits (112), Expect = 3e-05 Identities = 29/107 (27%), Positives = 53/107 (49%), Gaps = 5/107 (4%) Frame = +2 Query: 233 LVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLG 412 LV + L L+ + C +++ V + Q++ + + H + LHRD+KP N L+ Sbjct: 194 LVFEYLDSDLKQYLDHCGNLMNMHNVKIFMFQLLRGLAYCHRRKILHRDLKPQNLLI--- 250 Query: 413 RRANQVYVIDFGLAK-KYRDTSTHQH----IPYRENKNLTGTARYAS 538 ++ + DFGLA+ K T T+ + + YR L G+ Y++ Sbjct: 251 NERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYST 297
>PCTK3_MOUSE (Q04899) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 451 Score = 47.8 bits (112), Expect = 3e-05 Identities = 29/107 (27%), Positives = 53/107 (49%), Gaps = 5/107 (4%) Frame = +2 Query: 233 LVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLG 412 LV + L L+ + C +++ V + Q++ + + H + LHRD+KP N L+ Sbjct: 194 LVFEYLDSDLKQYLDHCGNLMNMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLLI--- 250 Query: 413 RRANQVYVIDFGLAK-KYRDTSTHQH----IPYRENKNLTGTARYAS 538 ++ + DFGLA+ K T T+ + + YR L G+ Y++ Sbjct: 251 NERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYST 297
>KBN8_YEAST (P38070) Probable serine/threonine-protein kinase YBR028C (EC| 2.7.11.1) Length = 525 Score = 47.8 bits (112), Expect = 3e-05 Identities = 32/103 (31%), Positives = 54/103 (52%), Gaps = 3/103 (2%) Frame = +2 Query: 305 TVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKK-YRDTSTH 481 TV A ++ + F+H+K ++RD+KP+N L+ + + + DFGL+KK D++ Sbjct: 253 TVSFYAAEISCALRFLHTKGVVYRDLKPENCLL---NQRGHLVLTDFGLSKKSANDSAVD 309 Query: 482 QHIPYRENK--NLTGTARYASVNTHLGIEQSRRDDLESLGYVL 604 + P N ++ GT Y + LG S+ D SLG +L Sbjct: 310 EEDPENVNALYSIIGTPEYCAPEILLGKAYSQNCDWYSLGCLL 352
>CCRK_RAT (Q4KM34) Cell cycle-related kinase (EC 2.7.11.22)| Length = 346 Score = 47.8 bits (112), Expect = 3e-05 Identities = 41/167 (24%), Positives = 74/167 (44%), Gaps = 10/167 (5%) Frame = +2 Query: 62 IYLGTNIQTNEEVGIK---LENVKTKHP-QLLYESKIYRILQGGTGIPNVRWFGVEGDYN 229 ++ +++T E V +K L ++ P Q L E K + ++ + ++ G Sbjct: 18 VFKAKHVETGEIVALKKVALRRLEDGIPNQALREIKALQEIEDSQYVVQLKAVFPHGAGF 77 Query: 230 VLVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGL 409 VL + + L ++ R L+ V ++ V F H+ + +HRD+KP N L+ Sbjct: 78 VLAFEFMLSDLAEVVRHAQRPLAPAQVKSYLQMLLKGVAFCHANNIVHRDLKPANLLIS- 136 Query: 410 GRRANQVYVIDFGLAKKYRDTS----THQHIP--YRENKNLTGTARY 532 + Q+ + DFGLA+ + THQ YR + L G +Y Sbjct: 137 --ASGQLKIADFGLARVFSPDGGRLYTHQVATRWYRAPELLYGARQY 181
>CCRK_MOUSE (Q9JHU3) Cell cycle-related kinase (EC 2.7.11.22)| (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) (CDK-related protein kinase PNQLARE) Length = 346 Score = 47.8 bits (112), Expect = 3e-05 Identities = 41/167 (24%), Positives = 74/167 (44%), Gaps = 10/167 (5%) Frame = +2 Query: 62 IYLGTNIQTNEEVGIK---LENVKTKHP-QLLYESKIYRILQGGTGIPNVRWFGVEGDYN 229 ++ +++T E V +K L ++ P Q L E K + ++ + ++ G Sbjct: 18 VFKAKHVETGEIVALKKVALRRLEDGIPNQALREIKALQEIEDSQYVVQLKAVFPHGAGF 77 Query: 230 VLVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGL 409 VL + + L ++ R L+ V ++ V F H+ + +HRD+KP N L+ Sbjct: 78 VLAFEFMLSDLAEVVRHAQRPLAPAQVKSYLQMLLKGVAFCHANNIVHRDLKPANLLIS- 136 Query: 410 GRRANQVYVIDFGLAKKYRDTS----THQHIP--YRENKNLTGTARY 532 + Q+ + DFGLA+ + THQ YR + L G +Y Sbjct: 137 --ASGQLKIADFGLARVFSPDGGRLYTHQVATRWYRAPELLYGARQY 181
>CDPK4_PLAYO (Q7RJG2) Calcium-dependent protein kinase 4 (EC 2.7.11.1)| Length = 527 Score = 47.8 bits (112), Expect = 3e-05 Identities = 50/190 (26%), Positives = 89/190 (46%), Gaps = 8/190 (4%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVK-----TKHPQLLYESKIYRILQGGTGIPNVRWFGVEGD 223 E+ L + T E IK+ + K T LL E ++ ++L I + F + + Sbjct: 82 EVILSKDKHTGHEYAIKVISKKHVKRKTDKQSLLREVELLKMLDH-INIMKLYEFFEDNN 140 Query: 224 YNVLVMDLLGPSLEDLFN-FCSRKLSLKT-VLMLADQMINRVEFVHSKSFLHRDIKPDNF 397 Y LV D+ +LF+ SRK + + Q+++ + ++H + +HRD+KP+N Sbjct: 141 YYYLVSDVYSGG--ELFDEIISRKRFYEVDAARIIKQVLSGITYMHKNNVVHRDLKPENI 198 Query: 398 LMGLGRRANQVY-VIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRR 574 L+ + + + +IDFGL STH ++ K+ GTA Y + + G + Sbjct: 199 LLETKNKEDMIIKIIDFGL-------STHFEYS-KKMKDKIGTAYYIAPDVLHG-TYDEK 249 Query: 575 DDLESLGYVL 604 D+ S G +L Sbjct: 250 CDIWSCGVIL 259
>CDPK4_PLABA (P62345) Calcium-dependent protein kinase 4 (EC 2.7.11.1) (PbCDPK4)| Length = 527 Score = 47.8 bits (112), Expect = 3e-05 Identities = 50/190 (26%), Positives = 89/190 (46%), Gaps = 8/190 (4%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVK-----TKHPQLLYESKIYRILQGGTGIPNVRWFGVEGD 223 E+ L + T E IK+ + K T LL E ++ ++L I + F + + Sbjct: 82 EVILSKDKHTGHEYAIKVISKKHVKRKTDKQSLLREVELLKMLDH-INIMKLYEFFEDNN 140 Query: 224 YNVLVMDLLGPSLEDLFN-FCSRKLSLKT-VLMLADQMINRVEFVHSKSFLHRDIKPDNF 397 Y LV D+ +LF+ SRK + + Q+++ + ++H + +HRD+KP+N Sbjct: 141 YYYLVSDVYSGG--ELFDEIISRKRFYEVDAARIIKQVLSGITYMHKNNVVHRDLKPENI 198 Query: 398 LMGLGRRANQVY-VIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRR 574 L+ + + + +IDFGL STH ++ K+ GTA Y + + G + Sbjct: 199 LLETKNKEDMIIKIIDFGL-------STHFEYS-KKMKDKIGTAYYIAPDVLHG-TYDEK 249 Query: 575 DDLESLGYVL 604 D+ S G +L Sbjct: 250 CDIWSCGVIL 259
>PCTK2_RAT (O35831) Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 2) Length = 523 Score = 47.4 bits (111), Expect = 3e-05 Identities = 30/107 (28%), Positives = 54/107 (50%), Gaps = 5/107 (4%) Frame = +2 Query: 233 LVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLG 412 LV + L L+ + C +S+ V + Q++ + + H + LHRD+KP N L+ Sbjct: 265 LVFEYLDKDLKQYMDDCGSIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLI--- 321 Query: 413 RRANQVYVIDFGLAK-KYRDTSTHQH----IPYRENKNLTGTARYAS 538 ++ + DFGLA+ K T T+ + + YR L G++ Y++ Sbjct: 322 NERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYST 368
>PK1_ASFM2 (P34206) Serine/threonine-protein kinase (EC 2.7.11.1)| Length = 299 Score = 47.4 bits (111), Expect = 3e-05 Identities = 33/128 (25%), Positives = 63/128 (49%) Frame = +2 Query: 149 ESKIYRILQGGTGIPNVRWFGVEGDYNVLVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQ 328 E + + LQ G+ + + Y++L+++ + S++ L +KL + Q Sbjct: 77 EVVVMKALQDTPGVIKLIEYTENAMYHILIIEYIPNSIDLLHYHYFKKLEENEAKKIIFQ 136 Query: 329 MINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENK 508 MI ++ ++ K F+H DIK +N ++ + ++ + VIDFG A + +T H Y Sbjct: 137 MILIIQNIYEKGFIHGDIKDENLIIDIDQKI--IKVIDFGSAVRLNET----HPQY---- 186 Query: 509 NLTGTARY 532 N+ GT Y Sbjct: 187 NMFGTWEY 194
>E2AK2_HUMAN (P19525) Interferon-induced, double-stranded RNA-activated protein| kinase (EC 2.7.11.1) (Interferon-inducible RNA-dependent protein kinase) (Protein kinase RNA-activated) (PKR) (p68 kinase) (P1/eIF-2A protein kinase) Length = 551 Score = 47.4 bits (111), Expect = 3e-05 Identities = 31/105 (29%), Positives = 47/105 (44%) Frame = +2 Query: 290 KLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYRD 469 KL L L +Q+ V+++HSK +HRD+KP N + QV + DFGL ++ Sbjct: 385 KLDKVLALELFEQITKGVDYIHSKKLIHRDLKPSNIFL---VDTKQVKIGDFGLVTSLKN 441 Query: 470 TSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGYVL 604 + GT RY S + + DL +LG +L Sbjct: 442 DG--------KRTRSKGTLRYMSPEQISSQDYGKEVDLYALGLIL 478
>ULK1_MOUSE (O70405) Serine/threonine-protein kinase ULK1 (EC 2.7.11.1)| (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1) Length = 1051 Score = 47.4 bits (111), Expect = 3e-05 Identities = 33/112 (29%), Positives = 51/112 (45%), Gaps = 6/112 (5%) Frame = +2 Query: 287 RKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGL--GRRAN----QVYVIDFG 448 R LS TV + Q+ + +HSK +HRD+KP N L+ GRRAN +V + DFG Sbjct: 108 RTLSEDTVRLFLQQIAGAMRLLHSKGIIHRDLKPQNILLSNPGGRRANPSNIRVKIADFG 167 Query: 449 LAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGYVL 604 A+ + L G+ Y + + + DL S+G ++ Sbjct: 168 FARYLQSNMM--------AATLCGSPMYMAPEVIMSQHYDGKADLWSIGTIV 211
>E2AK3_RAT (Q9Z1Z1) Eukaryotic translation initiation factor 2-alpha kinase 3| precursor (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) Length = 1108 Score = 47.4 bits (111), Expect = 3e-05 Identities = 36/124 (29%), Positives = 56/124 (45%), Gaps = 10/124 (8%) Frame = +2 Query: 263 EDLFNFCSRKLSL-----KTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQ 427 E+L ++ +R+ S+ + L + Q+ V+F+HSK +HRD+KP N + + Sbjct: 886 ENLKDWMNRRCSMEDREHRVCLHIFLQIAEAVQFLHSKGLMHRDLKPSNIFFTMD---DV 942 Query: 428 VYVIDFGLAKKYRDTSTHQHI-----PYRENKNLTGTARYASVNTHLGIEQSRRDDLESL 592 V V DFGL Q + Y + GT Y S G S + D+ SL Sbjct: 943 VKVGDFGLVTAMDQDEEEQTVLTPMPAYATHTGQVGTKLYMSPEQIHGNNYSHKVDIFSL 1002 Query: 593 GYVL 604 G +L Sbjct: 1003 GLIL 1006
>M3K8_MOUSE (Q07174) Mitogen-activated protein kinase kinase kinase 8 (EC| 2.7.11.25) (COT proto-oncogene serine/threonine-protein kinase) (C-COT) (Cancer Osaka thyroid oncogene) Length = 467 Score = 47.4 bits (111), Expect = 3e-05 Identities = 45/185 (24%), Positives = 82/185 (44%), Gaps = 1/185 (0%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLV 238 ++YL +++T + + KL + P + +R V W GD L Sbjct: 151 KVYLAQDMKTKKRMACKLIPIDQFKPSDVEIQACFRHENIAELYGAVLW----GDTVHLF 206 Query: 239 MDL-LGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGR 415 M+ G S+ + C + ++ + ++ ++F+HSK +H DIKP N + Sbjct: 207 MEAGEGGSVLEKLESCGPMREFE-IIWVTKHILKGLDFLHSKKVIHHDIKPSNIVF---- 261 Query: 416 RANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLG 595 + + ++DFGL+ K + ++P K+L GT Y S L S + D+ SLG Sbjct: 262 MSTKAVLVDFGLSVKMTE---DVYLP----KDLRGTEIYMSPEVILCRGHSTKADIYSLG 314 Query: 596 YVLMY 610 L++ Sbjct: 315 ATLIH 319
>E2AK3_HUMAN (Q9NZJ5) Eukaryotic translation initiation factor 2-alpha kinase 3| precursor (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) (HsPEK) Length = 1115 Score = 47.4 bits (111), Expect = 3e-05 Identities = 32/98 (32%), Positives = 43/98 (43%), Gaps = 5/98 (5%) Frame = +2 Query: 326 QMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYRDTSTHQHI----- 490 Q+ VEF+HSK +HRD+KP N + + V V DFGL Q + Sbjct: 919 QIAEAVEFLHSKGLMHRDLKPSNIFFTMD---DVVKVGDFGLVTAMDQDEEEQTVLTPMP 975 Query: 491 PYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGYVL 604 Y + GT Y S G S + D+ SLG +L Sbjct: 976 AYARHTGQVGTKLYMSPEQIHGNSYSHKVDIFSLGLIL 1013
>CDC2_VIGUN (P52389) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 47.4 bits (111), Expect = 3e-05 Identities = 29/84 (34%), Positives = 46/84 (54%), Gaps = 5/84 (5%) Frame = +2 Query: 302 KTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYR---DT 472 + V M Q++ + + HS LHRD+KP N L + RR N + + DFGLA+ + T Sbjct: 102 RQVKMFLYQILCGIAYCHSHRVLHRDLKPQNLL--IDRRTNSLKLADFGLARAFGIPVRT 159 Query: 473 STHQHIP--YRENKNLTGTARYAS 538 TH+ + YR + L G+ Y++ Sbjct: 160 FTHEVVTLWYRAPEILLGSRHYST 183
>CDC2_VIGAC (Q41639) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 47.4 bits (111), Expect = 3e-05 Identities = 29/84 (34%), Positives = 46/84 (54%), Gaps = 5/84 (5%) Frame = +2 Query: 302 KTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYR---DT 472 + V M Q++ + + HS LHRD+KP N L + RR N + + DFGLA+ + T Sbjct: 102 RQVKMFLYQILCGIAYCHSHRVLHRDLKPQNLL--IDRRTNSLKLADFGLARAFGIPVRT 159 Query: 473 STHQHIP--YRENKNLTGTARYAS 538 TH+ + YR + L G+ Y++ Sbjct: 160 FTHEVVTLWYRAPEILLGSRHYST 183
>CDC2H_THEPA (Q27032) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 298 Score = 47.4 bits (111), Expect = 3e-05 Identities = 31/107 (28%), Positives = 51/107 (47%), Gaps = 5/107 (4%) Frame = +2 Query: 233 LVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLG 412 LV + L L+ L + C L T Q++ + + H LHRD+KP N L+ Sbjct: 77 LVFEYLDQDLKKLLDACDGGLEPTTAKSFLYQILRGISYCHDHRILHRDLKPQNLLI--- 133 Query: 413 RRANQVYVIDFGLAKKYR---DTSTHQHIP--YRENKNLTGTARYAS 538 R + + DFGLA+ + + TH+ + YR L G+ +Y++ Sbjct: 134 NREGVLKLADFGLARAFAIPVRSYTHEVVTLWYRAPDVLMGSKKYST 180
>CDC2H_THEAN (Q26671) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 298 Score = 47.4 bits (111), Expect = 3e-05 Identities = 31/107 (28%), Positives = 51/107 (47%), Gaps = 5/107 (4%) Frame = +2 Query: 233 LVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLG 412 LV + L L+ L + C L T Q++ + + H LHRD+KP N L+ Sbjct: 77 LVFEYLDQDLKKLLDACDGGLEPTTAKSFLYQILRGISYCHDHRILHRDLKPQNLLI--- 133 Query: 413 RRANQVYVIDFGLAKKYR---DTSTHQHIP--YRENKNLTGTARYAS 538 R + + DFGLA+ + + TH+ + YR L G+ +Y++ Sbjct: 134 NREGVLKLADFGLARAFAIPVRSYTHEVVTLWYRAPDVLMGSKKYST 180
>KPK19_ARATH (Q39030) Serine/threonine-protein kinase AtPK19 (EC 2.7.11.1)| (Ribosomal-protein S6 kinase homolog) Length = 471 Score = 47.4 bits (111), Expect = 3e-05 Identities = 26/93 (27%), Positives = 47/93 (50%) Frame = +2 Query: 326 QMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYREN 505 ++++ V +H K +HRD+KP+N LM + V + DFGLAK++ + + + Sbjct: 246 EIVSAVSHLHEKGIMHRDLKPENILMDVD---GHVMLTDFGLAKEFEENT--------RS 294 Query: 506 KNLTGTARYASVNTHLGIEQSRRDDLESLGYVL 604 ++ GT Y + G + D S+G +L Sbjct: 295 NSMCGTTEYMAPEIVRGKGHDKAADWWSVGILL 327
>CDK4_XENLA (Q91727) Cell division protein kinase 4 (EC 2.7.11.22)| (Cyclin-dependent kinase 4) Length = 319 Score = 47.4 bits (111), Expect = 3e-05 Identities = 24/57 (42%), Positives = 36/57 (63%) Frame = +2 Query: 293 LSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKY 463 L L+T+ L Q ++ +EF+H +HRD+KP+N L+ G QV + DFGLA+ Y Sbjct: 112 LPLETIKDLMKQFLSGLEFLHLNCIVHRDLKPENILVTSG---GQVKLADFGLARIY 165
>CDPK4_PLAF7 (Q8IBS5) Calcium-dependent protein kinase 4 (EC 2.7.11.1)| Length = 527 Score = 47.4 bits (111), Expect = 3e-05 Identities = 51/190 (26%), Positives = 88/190 (46%), Gaps = 8/190 (4%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVK-----TKHPQLLYESKIYRILQGGTGIPNVRWFGVEGD 223 E+ L + T E IK+ + K T LL E ++ ++L I + F + + Sbjct: 82 EVILSRDKHTGHEYAIKVISKKHVKRKTDKESLLREVELLKMLDH-INIMKLYEFFEDNN 140 Query: 224 YNVLVMDLL-GPSLEDLFNFCSRKLSLKT-VLMLADQMINRVEFVHSKSFLHRDIKPDNF 397 Y LV D+ G L D SRK + + Q+++ + ++H + +HRD+KP+N Sbjct: 141 YYYLVSDVYTGGELFD--EIISRKRFYEIDAARIIKQILSGITYMHKNNVVHRDLKPENI 198 Query: 398 LMGLGRRANQVY-VIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRR 574 L+ + + + +IDFGL STH ++ K+ GTA Y + + G + Sbjct: 199 LLETKNKEDMIIKIIDFGL-------STHFEYS-KKMKDKIGTAYYIAPDVLHG-TYDEK 249 Query: 575 DDLESLGYVL 604 D+ S G +L Sbjct: 250 CDIWSCGVIL 259
>E2AK2_MOUSE (Q03963) Interferon-induced, double-stranded RNA-activated protein| kinase (EC 2.7.11.1) (Interferon-inducible RNA-dependent protein kinase) (Protein kinase RNA-activated) (PKR) (p68 kinase) (P1/eIF-2A protein kinase) (Serine/threonine-protein Length = 515 Score = 47.0 bits (110), Expect = 4e-05 Identities = 30/105 (28%), Positives = 49/105 (46%) Frame = +2 Query: 290 KLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYRD 469 K+ +L L +Q++ VE++HSK +HRD+KP N + R + + DFGLA + Sbjct: 347 KVDKALILDLYEQIVTGVEYIHSKGLIHRDLKPGNIFLVDER---HIKIGDFGLATALEN 403 Query: 470 TSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGYVL 604 + TGT +Y S + D+ +LG +L Sbjct: 404 DG-------KSRTRRTGTLQYMSPEQLFLKHYGKEVDIFALGLIL 441
>KSG1_SCHPO (Q12701) Serine/threonine-protein kinase ksg1 (EC 2.7.11.1)| Length = 592 Score = 47.0 bits (110), Expect = 4e-05 Identities = 22/77 (28%), Positives = 41/77 (53%), Gaps = 7/77 (9%) Frame = +2 Query: 329 MINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAK-------KYRDTSTHQH 487 +++ ++++H + +HRD+KP+N L+ R + DFG AK + + + H Sbjct: 207 IVDSIDYMHGRGVIHRDLKPENILLDDNMRTK---ITDFGSAKILNSSHGSHEEDTHHAD 263 Query: 488 IPYRENKNLTGTARYAS 538 P +++ GTARY S Sbjct: 264 KPQAHSRSFVGTARYVS 280
>PKN3_MYXXA (Q9XBQ0) Serine/threonine-protein kinase pkn3 (EC 2.7.11.1)| Length = 547 Score = 47.0 bits (110), Expect = 4e-05 Identities = 34/117 (29%), Positives = 55/117 (47%), Gaps = 3/117 (2%) Frame = +2 Query: 263 EDLFNFCSRKLSLKT--VLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGR-RANQVY 433 +DL SR+ L V+ + Q+++ + H +HRD+KP+N ++ R + V Sbjct: 102 QDLHQILSREWPLNEGRVVRIVSQVLSALSDAHGAGVIHRDLKPENIMVEPRRNEPDFVK 161 Query: 434 VIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGYVL 604 V+DFG+AK ST + GT Y S G + R DL ++G +L Sbjct: 162 VLDFGIAK--ITDSTDDGPALTRAGFVCGTPEYMSPEQARGSQLDHRSDLYAVGVIL 216
>STK6_HUMAN (O14965) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1) (Aurora-related kinase 1) (hARK1) (Aurora-A) (Breast-tumor-amplified kinase) Length = 403 Score = 47.0 bits (110), Expect = 4e-05 Identities = 32/95 (33%), Positives = 44/95 (46%) Frame = +2 Query: 326 QMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYREN 505 ++ N + + HSK +HRDIKP+N L+G A ++ + DFG + H P Sbjct: 239 ELANALSYCHSKRVIHRDIKPENLLLG---SAGELKIADFGWS---------VHAPSSRR 286 Query: 506 KNLTGTARYASVNTHLGIEQSRRDDLESLGYVLMY 610 L GT Y G + DL SLG VL Y Sbjct: 287 TTLCGTLDYLPPEMIEGRMHDEKVDLWSLG-VLCY 320
>GCN2_SCHPO (Q9HGN1) Serine/threonine-protein kinase gcn2 (EC 2.7.11.1)| Length = 1576 Score = 47.0 bits (110), Expect = 4e-05 Identities = 35/125 (28%), Positives = 63/125 (50%), Gaps = 9/125 (7%) Frame = +2 Query: 257 SLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYV 436 SL+D+ K+ + + L Q++ + ++HS+ +HRD+KP N + R V + Sbjct: 735 SLQDIIR---DKIPVDEMWRLFRQILEALAYIHSRGMMHRDLKPGNIFLDENR---NVKL 788 Query: 437 IDFGLA---KKYRDTSTHQHIPYRENKNLT---GTARYAS---VNTHLGIEQSRRDDLES 589 DFGLA + Y+D + +++LT GTA Y + ++ G+ + D+ S Sbjct: 789 GDFGLATENENYQDNNDKWKNRQSADEDLTTGVGTALYVAPELLSRRNGVRYDAKVDMYS 848 Query: 590 LGYVL 604 LG +L Sbjct: 849 LGIIL 853
>AAPK1_CAEEL (P45894) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMP-activated kinase 1) Length = 589 Score = 47.0 bits (110), Expect = 4e-05 Identities = 39/155 (25%), Positives = 70/155 (45%), Gaps = 22/155 (14%) Frame = +2 Query: 71 GTNIQTNEEVGIKLEN--------------------VKTKHPQLLYESKIYRILQGGTGI 190 GT+IQT +V IK+ N K HP + ++++R++ + I Sbjct: 41 GTHIQTGYDVAIKILNRGRMKGLGTVNKTRNEIDNLQKLTHPHI---TRLFRVISTPSDI 97 Query: 191 PNVRWFGVEGDYNVLVMDLLGPSLEDLFNFCSRK--LSLKTVLMLADQMINRVEFVHSKS 364 LVM+L+ +LF++ +RK L ++ Q+I+ V + H+ Sbjct: 98 -------------FLVMELVSGG--ELFSYITRKGALPIRESRRYFQQIISGVSYCHNHM 142 Query: 365 FLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYRD 469 +HRD+KP+N L+ + + + DFGL+ D Sbjct: 143 IVHRDLKPENLLLDANK---NIKIADFGLSNYMTD 174
>RAN1_SCHPO (P08092) Negative regulator of sexual conjugation and meiosis (EC| 2.7.11.1) Length = 470 Score = 47.0 bits (110), Expect = 4e-05 Identities = 28/70 (40%), Positives = 39/70 (55%), Gaps = 7/70 (10%) Frame = +2 Query: 266 DLFNFCSRKLS-------LKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRAN 424 DLF + + K +KTV + Q+I+ VE HS HRD+KP+N + +G N Sbjct: 102 DLFTYITEKKVYQGNSHLIKTVFL---QLISAVEHCHSVGIYHRDLKPENIM--VGNDVN 156 Query: 425 QVYVIDFGLA 454 VY+ DFGLA Sbjct: 157 TVYLADFGLA 166
>PAK1_MOUSE (O88643) Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1)| (p21-activated kinase 1) (PAK-1) (P65-PAK) (Alpha-PAK) (CDC42/RAC effector kinase PAK-A) Length = 545 Score = 46.6 bits (109), Expect = 6e-05 Identities = 37/131 (28%), Positives = 64/131 (48%), Gaps = 2/131 (1%) Frame = +2 Query: 62 IYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQG-GTGIPNVRWFGVEGDYNVLV 238 +Y ++ T +EV IK N++ + + L ++I + + I N + GD +V Sbjct: 284 VYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVV 343 Query: 239 MDLL-GPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGR 415 M+ L G SL D+ + + + + + +EF+HS +HRDIK DN L+G+ Sbjct: 344 MEYLAGGSLTDVVT--ETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMD- 400 Query: 416 RANQVYVIDFG 448 V + DFG Sbjct: 401 --GSVKLTDFG 409
>PAK1_HUMAN (Q13153) Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1)| (p21-activated kinase 1) (PAK-1) (P65-PAK) (Alpha-PAK) Length = 545 Score = 46.6 bits (109), Expect = 6e-05 Identities = 37/131 (28%), Positives = 64/131 (48%), Gaps = 2/131 (1%) Frame = +2 Query: 62 IYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQG-GTGIPNVRWFGVEGDYNVLV 238 +Y ++ T +EV IK N++ + + L ++I + + I N + GD +V Sbjct: 284 VYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVV 343 Query: 239 MDLL-GPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGR 415 M+ L G SL D+ + + + + + +EF+HS +HRDIK DN L+G+ Sbjct: 344 MEYLAGGSLTDVVT--ETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMD- 400 Query: 416 RANQVYVIDFG 448 V + DFG Sbjct: 401 --GSVKLTDFG 409
>MKK2_YEAST (P32491) MAP kinase kinase MKK2/SSP33 (EC 2.7.12.2)| Length = 506 Score = 46.6 bits (109), Expect = 6e-05 Identities = 42/177 (23%), Positives = 83/177 (46%), Gaps = 11/177 (6%) Frame = +2 Query: 110 LENVKTKHPQLLYESKIYRILQGGTGIPN---VRWFGVEGDYN----VLVMDLLG-PSLE 265 L+ + T + Y+ +I+R LQ + V+++G+ D + M+ +G SLE Sbjct: 242 LKTINTMNTDPEYQKQIFRELQFNKSFKSDYIVQYYGMFTDEQSSSIYIAMEYMGGKSLE 301 Query: 266 DLF-NFCSR--KLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYV 436 + N R ++S + + +A+ ++ + ++H + +HRDIKP N L+ ++ + Sbjct: 302 ATYKNLLKRGGRISERVIGKIAESVLRGLSYLHERKVIHRDIKPQNILL---NEKGEIKL 358 Query: 437 IDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGYVLM 607 DFG++ + ++ TGT+ Y + G S D+ SLG L+ Sbjct: 359 CDFGVSGEAVNSLA---------MTFTGTSFYMAPERIQGQPYSVTCDVWSLGLTLL 406
>KCC1_YEAST (P27466) Calcium/calmodulin-dependent protein kinase I (EC| 2.7.11.17) Length = 446 Score = 46.6 bits (109), Expect = 6e-05 Identities = 33/136 (24%), Positives = 65/136 (47%), Gaps = 6/136 (4%) Frame = +2 Query: 77 NIQTNEEVGIK------LENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLV 238 N +T E+V +K L+ K + L E I + L + WF + + ++ Sbjct: 56 NTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLHHPNIVAFKDWFESKDKFYIIT 115 Query: 239 MDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRR 418 G L D K + + + + ++++ V+++HS++ +HRD+KP+N L Sbjct: 116 QLAKGGELFDRI-LKKGKFTEEDAVRILVEILSAVKYMHSQNIVHRDLKPENLLYIDKSD 174 Query: 419 ANQVYVIDFGLAKKYR 466 + + V DFG+AK+ + Sbjct: 175 ESPLVVADFGIAKRLK 190
>PAK1_RAT (P35465) Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1)| (p21-activated kinase 1) (PAK-1) (P68-PAK) (Alpha-PAK) (Protein kinase MUK2) Length = 544 Score = 46.6 bits (109), Expect = 6e-05 Identities = 37/131 (28%), Positives = 64/131 (48%), Gaps = 2/131 (1%) Frame = +2 Query: 62 IYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQG-GTGIPNVRWFGVEGDYNVLV 238 +Y ++ T +EV IK N++ + + L ++I + + I N + GD +V Sbjct: 283 VYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVV 342 Query: 239 MDLL-GPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGR 415 M+ L G SL D+ + + + + + +EF+HS +HRDIK DN L+G+ Sbjct: 343 MEYLAGGSLTDVVT--ETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMD- 399 Query: 416 RANQVYVIDFG 448 V + DFG Sbjct: 400 --GSVKLTDFG 408
>KPK1_ARATH (P42818) Serine/threonine-protein kinase AtPK1/AtPK6 (EC 2.7.11.1)| Length = 465 Score = 46.6 bits (109), Expect = 6e-05 Identities = 26/93 (27%), Positives = 46/93 (49%) Frame = +2 Query: 326 QMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYREN 505 ++++ V +H K +HRD+KP+N LM V + DFGLAK++ + + + Sbjct: 240 EIVSAVSHLHEKGIMHRDLKPENILMDTD---GHVMLTDFGLAKEFEENT--------RS 288 Query: 506 KNLTGTARYASVNTHLGIEQSRRDDLESLGYVL 604 ++ GT Y + G + D S+G +L Sbjct: 289 NSMCGTTEYMAPEIVRGKGHDKAADWWSVGILL 321
>BUR1_CANAL (Q9Y7W4) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 746 Score = 46.6 bits (109), Expect = 6e-05 Identities = 24/68 (35%), Positives = 40/68 (58%) Frame = +2 Query: 290 KLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYRD 469 KL L + + Q++ +++VH++ FLHRDIK N L+G + + + DFGLA+ Y Sbjct: 150 KLELGQIKCIMQQLLKGIQYVHNQKFLHRDIKAANILIG---QDGVLKIADFGLARIY-- 204 Query: 470 TSTHQHIP 493 H ++P Sbjct: 205 ---HGNVP 209
>MEK1_YEAST (P24719) Meiosis-specific serine/threonine-protein kinase MEK1 (EC| 2.7.11.1) Length = 497 Score = 46.6 bits (109), Expect = 6e-05 Identities = 31/122 (25%), Positives = 51/122 (41%), Gaps = 11/122 (9%) Frame = +2 Query: 266 DLFNF-----CSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQV 430 DLF++ C +S L++ Q++ + ++H + +HRD+K DN L+ ++ Sbjct: 248 DLFSYLAKGDCLTSMSETESLLIVFQILQALNYLHDQDIVHRDLKLDNILLCTPEPCTRI 307 Query: 431 YVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYAS------VNTHLGIEQSRRDDLESL 592 + DFG+AK H + GT Y + N SR LE Sbjct: 308 VLADFGIAKDLNSNKERMH-------TVVGTPEYCAPEVGFRANRKAYQSFSRAATLEQR 360 Query: 593 GY 598 GY Sbjct: 361 GY 362
>CD2L7_HUMAN (Q9NYV4) Cell division cycle 2-related protein kinase 7 (EC| 2.7.11.22) (CDC2-related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS) Length = 1490 Score = 46.6 bits (109), Expect = 6e-05 Identities = 26/75 (34%), Positives = 40/75 (53%), Gaps = 6/75 (8%) Frame = +2 Query: 326 QMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYRDTSTHQH------ 487 Q++ +E+ H K+FLHRDIK N L+ + Q+ + DFGLA+ Y + + Sbjct: 842 QLMEGLEYCHKKNFLHRDIKCSNILL---NNSGQIKLADFGLARLYNSEESRPYTNKVIT 898 Query: 488 IPYRENKNLTGTARY 532 + YR + L G RY Sbjct: 899 LWYRPPELLLGEERY 913
>MOS_MSVMH (P07331) Serine/threonine-protein kinase transforming protein mos| (EC 2.7.11.1) Length = 374 Score = 46.6 bits (109), Expect = 6e-05 Identities = 31/108 (28%), Positives = 53/108 (49%) Frame = +2 Query: 281 CSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKK 460 C +LSL L + ++N + F+HS+S LH D+KP N L+ + + DFG ++K Sbjct: 197 CREQLSLGKCLKYSLDVVNGLLFLHSQSILHLDLKPANILIS---EQDVCKISDFGCSQK 253 Query: 461 YRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGYVL 604 +D Q P+ ++ GT + + G + + D+ S G L Sbjct: 254 LQDLRCRQASPH----HIGGTYTHQAPEILKGEIATPKADIYSFGITL 297
>NEK9_XENLA (Q7ZZC8) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)| (NimA-related protein kinase 9) (XNek9) (Nercc1 kinase) Length = 944 Score = 46.6 bits (109), Expect = 6e-05 Identities = 39/132 (29%), Positives = 64/132 (48%), Gaps = 4/132 (3%) Frame = +2 Query: 221 DYNVLVMDLLGPSLEDLFN-FCSRKLSL---KTVLMLADQMINRVEFVHSKSFLHRDIKP 388 D N L+++L + +LF+ +K L +TVL Q+++ V +H LHRDIK Sbjct: 102 DSNTLLIELEYCNGGNLFDKIVHQKAQLFQEETVLWYLFQIVSAVSCIHKAGILHRDIKT 161 Query: 389 DNFLMGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQS 568 N + +AN + + D+GLAK+ Y + GT Y S G++ S Sbjct: 162 LNIFL---TKANLIKLGDYGLAKQLSS-------EYSMAETCVGTLYYMSPEICQGVKYS 211 Query: 569 RRDDLESLGYVL 604 + D+ ++G VL Sbjct: 212 FKSDIWAVGCVL 223
>KCC1_EMENI (Q00771) Calcium/calmodulin-dependent protein kinase (EC 2.7.11.17)| (CMPK) Length = 414 Score = 46.6 bits (109), Expect = 6e-05 Identities = 34/136 (25%), Positives = 61/136 (44%), Gaps = 1/136 (0%) Frame = +2 Query: 197 VRWFGVEGDYNVLVMDLLGPSLEDLFNFCSR-KLSLKTVLMLADQMINRVEFVHSKSFLH 373 V WF + + ++ G L D C K + K Q+++ V ++H ++ +H Sbjct: 83 VDWFESKDKFYIVTQLATGGELFD--RICEYGKFTEKDASQTIRQVLDAVNYLHQRNIVH 140 Query: 374 RDIKPDNFLMGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHL 553 RD+KP+N L +Q+ + DFG+AK + P ++ G+ YA+ L Sbjct: 141 RDLKPENLLYLTRDLDSQLVLADFGIAKMLDN-------PAEVLTSMAGSFGYAAPEVML 193 Query: 554 GIEQSRRDDLESLGYV 601 + D+ SLG + Sbjct: 194 KQGHGKAVDIWSLGVI 209
>AFC1_ARATH (P51566) Serine/threonine-protein kinase AFC1 (EC 2.7.12.1)| Length = 467 Score = 46.6 bits (109), Expect = 6e-05 Identities = 39/163 (23%), Positives = 75/163 (46%), Gaps = 19/163 (11%) Frame = +2 Query: 176 GGTGIPNVR-WFGVEGDYNVLVMDLLGPSLEDLFNFCS-RKLSLKTVLMLADQMINRVEF 349 GG+ +R WF ++ +V + LGPSL D S R + V L Q++ V + Sbjct: 172 GGSRCVQIRNWFDYR-NHICIVFEKLGPSLYDFLRKNSYRSFPIDLVRELGRQLLESVAY 230 Query: 350 VHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFG-LAKKYRDTSTHQHIP----------- 493 +H +H D+KP+N L+ + + + D+ L++ +D S +++P Sbjct: 231 MHDLRLIHTDLKPENILL---VSSEYIKIPDYKFLSRPTKDGSYFKNLPKSSAIKLIDFG 287 Query: 494 -----YRENKNLTGTARYASVNTHLGIEQSRRDDLESLGYVLM 607 ++++ + T Y + LG+ + DL S+G +L+ Sbjct: 288 STTFEHQDHNYIVSTRHYRAPEVILGVGWNYPCDLWSIGCILV 330
>PDK1L_BRARE (Q32PP3) Serine/threonine-protein kinase pdik1l (EC 2.7.11.1)| Length = 341 Score = 46.6 bits (109), Expect = 6e-05 Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 5/86 (5%) Frame = +2 Query: 284 SRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRR-----ANQVYVIDFG 448 SRK S KT Q+ + + F+H +HRD+KPDN L+ GR + V DFG Sbjct: 133 SRKPSRKTNTSFMLQLGSALAFLHRNQIIHRDLKPDNILISQGRTPAGSPEPTLKVADFG 192 Query: 449 LAKKYRDTSTHQHIPYRENKNLTGTA 526 L+K + + P NK TA Sbjct: 193 LSKVCSGSGLNPEEPASVNKCFLSTA 218
>CDC22_ORYSA (P29619) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| Length = 292 Score = 46.6 bits (109), Expect = 6e-05 Identities = 27/76 (35%), Positives = 42/76 (55%), Gaps = 5/76 (6%) Frame = +2 Query: 326 QMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYR---DTSTHQHIP- 493 Q++ + + HS LHRD+KP N L + RR N + + DFGLA+ + T TH+ + Sbjct: 109 QILRGIAYCHSHRVLHRDLKPQNLL--IDRRTNSLKLADFGLARAFGIPVRTFTHEVVTL 166 Query: 494 -YRENKNLTGTARYAS 538 YR + L G Y++ Sbjct: 167 WYRAPEILLGARHYST 182
>MOS_MSVMM (P00537) Serine/threonine-protein kinase transforming protein mos| (EC 2.7.11.1) Length = 376 Score = 46.6 bits (109), Expect = 6e-05 Identities = 31/108 (28%), Positives = 53/108 (49%) Frame = +2 Query: 281 CSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKK 460 C +LSL L + ++N + F+HS+S LH D+KP N L+ + + DFG ++K Sbjct: 197 CREQLSLGKCLKYSLDVVNGLLFLHSQSILHLDLKPANILIS---EQDVCKISDFGCSQK 253 Query: 461 YRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGYVL 604 +D Q P+ ++ GT + + G + + D+ S G L Sbjct: 254 LQDLRCRQASPH----HIGGTYTHQAPEILKGEIATPKADIYSFGITL 297
>CSK2A_SCHPO (P40231) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II alpha| subunit) Length = 332 Score = 46.6 bits (109), Expect = 6e-05 Identities = 34/136 (25%), Positives = 68/136 (50%), Gaps = 1/136 (0%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLV 238 E++ G N+ N + IK+ K+ ++ E KI + L GG I + + D Sbjct: 56 EVFEGLNVLNNSKCIIKVLK-PVKYKKIKREIKILQNLAGGPNI--ISLLDIVRDPESKT 112 Query: 239 MDLLGPSLEDL-FNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGR 415 L+ ++++ F LS + + +++ ++F HS+ +HRD+KP N + + Sbjct: 113 PSLIFEFVDNIDFRTLYPTLSDYDIRYYSYELLKALDFCHSRGIMHRDVKPHNVM--IDH 170 Query: 416 RANQVYVIDFGLAKKY 463 + ++ +ID+GLA+ Y Sbjct: 171 KKRKLRLIDWGLAEFY 186
>CDC2A_ARATH (P24100) Cell division control protein 2 homolog A (EC 2.7.11.22)| (EC 2.7.11.23) Length = 294 Score = 46.6 bits (109), Expect = 6e-05 Identities = 27/76 (35%), Positives = 43/76 (56%), Gaps = 5/76 (6%) Frame = +2 Query: 326 QMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYR---DTSTHQHIP- 493 Q++ + + HS LHRD+KP N L + RR N + + DFGLA+ + T TH+ + Sbjct: 110 QILRGIAYCHSHRVLHRDLKPQNLL--IDRRTNSLKLADFGLARAFGIPVRTFTHEVVTL 167 Query: 494 -YRENKNLTGTARYAS 538 YR + L G+ Y++ Sbjct: 168 WYRAPEILLGSHHYST 183
>ST17B_MOUSE (Q8BG48) Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP| kinase-related apoptosis-inducing protein kinase 2) Length = 372 Score = 46.6 bits (109), Expect = 6e-05 Identities = 25/93 (26%), Positives = 46/93 (49%), Gaps = 4/93 (4%) Frame = +2 Query: 266 DLFNFCSRKL----SLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVY 433 ++FN C +L S V+ L Q++ V ++H + +H D+KP N L+ + Sbjct: 117 EIFNLCLPELAEMVSENDVIRLIKQILEGVHYLHQNNIVHLDLKPQNILLSSIYPLGDIK 176 Query: 434 VIDFGLAKKYRDTSTHQHIPYRENKNLTGTARY 532 ++DFG+++K + S E + + GT Y Sbjct: 177 IVDFGMSRKIGNAS--------ELREIMGTPEY 201
>ST17B_RAT (Q91XS8) Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP| kinase-related apoptosis-inducing protein kinase 2) Length = 371 Score = 46.6 bits (109), Expect = 6e-05 Identities = 25/93 (26%), Positives = 46/93 (49%), Gaps = 4/93 (4%) Frame = +2 Query: 266 DLFNFCSRKL----SLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVY 433 ++FN C +L S V+ L Q++ V ++H + +H D+KP N L+ + Sbjct: 117 EIFNLCLPELAEMVSENDVIRLIKQILEGVHYLHQNNIVHLDLKPQNILLSSIYPLGDIK 176 Query: 434 VIDFGLAKKYRDTSTHQHIPYRENKNLTGTARY 532 ++DFG+++K + S E + + GT Y Sbjct: 177 IVDFGMSRKIGNAS--------ELREIMGTPEY 201
>PKH3_YEAST (Q03306) Serine/threonine-protein kinase PKH3 (EC 2.7.11.1)| (Pkb-activating kinase homolog 3) Length = 898 Score = 46.6 bits (109), Expect = 6e-05 Identities = 29/106 (27%), Positives = 49/106 (46%), Gaps = 10/106 (9%) Frame = +2 Query: 326 QMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYREN 505 Q+I+ +EF+HS +HRD+KP+N L+ R ++ + DFG A + + + + Sbjct: 121 QLIDALEFIHSHGIIHRDLKPENVLLD---RDGRLMITDFGAAATIDPSLSGDSAKFNSD 177 Query: 506 KN----------LTGTARYASVNTHLGIEQSRRDDLESLGYVLMYF 613 N GTA Y S L + D+ +LG ++ F Sbjct: 178 SNGSKDNQNCASFVGTAEYVSPELLLYNQCGYGSDIWALGCMIYQF 223
>MKNK1_XENLA (Q9YGW0) MAP kinase-interacting serine/threonine-protein kinase 1| (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (Mnk1) Length = 418 Score = 46.6 bits (109), Expect = 6e-05 Identities = 48/189 (25%), Positives = 82/189 (43%), Gaps = 13/189 (6%) Frame = +2 Query: 77 NIQTNEEVGIKLENVKTKHPQLLYESKIYRIL------QGGTGIPNVRWFGVEGDYNVLV 238 ++Q ++ +K+ K H + S+++R + QG I + F + LV Sbjct: 56 SLQNGKDYAVKIVEKKAGHSR----SRVFREVETLYQCQGNKNILELIEFCEDDARFYLV 111 Query: 239 MD-LLGPSLEDLFNFCSRK-LSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLG 412 + LLG S+ L + RK + + + + + ++F+H+K HRD+KP+N L Sbjct: 112 FEKLLGGSI--LSHIQKRKHFNEREASKVVKDIASALDFLHTKGIAHRDLKPENILCEFK 169 Query: 413 RRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARY-----ASVNTHLGIEQSRRD 577 + + V + DF L + S I E G+A Y V T +R Sbjct: 170 DKVSPVKICDFDLGSGVKLNSACTTITTPELTTPCGSAEYMAPEVVEVFTEEATFYDKRC 229 Query: 578 DLESLGYVL 604 DL SLG +L Sbjct: 230 DLWSLGVIL 238
>CHK1_XENLA (Q6DE87) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (xChk1| protein) Length = 474 Score = 46.2 bits (108), Expect = 8e-05 Identities = 38/140 (27%), Positives = 67/140 (47%), Gaps = 4/140 (2%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKH--PQLLYESKIYRILQGGTGIPNVRWFGVEGDYNV 232 E+ L N +T E V +K+ ++ P+ + + + T I VR++G + N+ Sbjct: 22 EVQLAVNRKTEEAVAVKIVDMTRAADCPENIKKEICINRMLSHTNI--VRFYGHRREGNI 79 Query: 233 LVMDLLGPSLEDLFNFCSRKLSL--KTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMG 406 + L +LF+ + + + Q+I VE++HS HRDIKP+N L+ Sbjct: 80 QYLFLEYCRGGELFDRIEPDVGMPEQDAQKFFQQLIAGVEYLHSIGITHRDIKPENLLLD 139 Query: 407 LGRRANQVYVIDFGLAKKYR 466 +Q+ + DFGLA +R Sbjct: 140 ---ERDQLKISDFGLATVFR 156
>CCRK_PONPY (Q5R7I7) Cell cycle-related kinase (EC 2.7.11.22)| Length = 346 Score = 46.2 bits (108), Expect = 8e-05 Identities = 40/167 (23%), Positives = 73/167 (43%), Gaps = 10/167 (5%) Frame = +2 Query: 62 IYLGTNIQTNEEVGIK---LENVKTKHP-QLLYESKIYRILQGGTGIPNVRWFGVEGDYN 229 ++ +++T E V +K L ++ P Q L E K + ++ + ++ Sbjct: 18 VFKAKHVETGEIVALKKVALRRLEDGIPNQALREIKALQEMEDNQYVVQLKAVFPHSAGF 77 Query: 230 VLVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGL 409 VL + + L ++ R L+ V ++ V F H+ + +HRD+KP N L+ Sbjct: 78 VLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVSFCHANNIVHRDLKPANLLIS- 136 Query: 410 GRRANQVYVIDFGLAKKYRDTS----THQHIP--YRENKNLTGTARY 532 + Q+ + DFGLA+ + THQ YR + L G +Y Sbjct: 137 --ASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGARQY 181
>M3K8_RAT (Q63562) Mitogen-activated protein kinase kinase kinase 8 (EC| 2.7.11.25) (Tumor progression locus 2) (TPL-2) Length = 467 Score = 46.2 bits (108), Expect = 8e-05 Identities = 45/185 (24%), Positives = 82/185 (44%), Gaps = 1/185 (0%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLV 238 ++YL +++T + + KL V P + +R V W GD L Sbjct: 151 KVYLAQDMKTKKRMACKLIPVDQFKPSDVEIQACFRHENIAELYGAVLW----GDTVHLF 206 Query: 239 MDL-LGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGR 415 M+ G S+ + C + ++ + ++ ++F+HSK +H DIKP N + Sbjct: 207 MEAGEGGSVLEKLESCGPMREFE-IIWVTKHVLKGLDFLHSKKVIHHDIKPSNIVF---- 261 Query: 416 RANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLG 595 + + ++DFGL+ + + ++P K+L GT Y S L S + D+ SLG Sbjct: 262 MSTKAVLVDFGLSVQMTE---DVYLP----KDLRGTEIYMSPEVILCRGHSTKADIYSLG 314 Query: 596 YVLMY 610 L++ Sbjct: 315 ATLIH 319
>CDPK2_PLAF7 (Q8ICR0) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (PfCDPK2)| Length = 508 Score = 46.2 bits (108), Expect = 8e-05 Identities = 30/97 (30%), Positives = 51/97 (52%), Gaps = 5/97 (5%) Frame = +2 Query: 221 DYNVLVMDLLGPSLEDLFNFCSRKLSL--KTVLMLADQMINRVEFVHSKSFLHRDIKPDN 394 +Y L+M+L S +LF+ S K + Q+ + + ++HS + +HRD+KP+N Sbjct: 139 NYIYLIMELC--SGRELFDSIIENGSFTEKNAATIMKQIFSAIFYLHSLNIVHRDLKPEN 196 Query: 395 FLMGLGRRANQVYVIDFGLAKKY---RDTSTHQHIPY 496 FL + + + +IDFGL+K T+T PY Sbjct: 197 FLFQSENKDSLLKIIDFGLSKNLGTGEFTTTKAGTPY 233
>CDPK2_PLAFK (O15865) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (PfCDPK2)| Length = 512 Score = 46.2 bits (108), Expect = 8e-05 Identities = 30/97 (30%), Positives = 51/97 (52%), Gaps = 5/97 (5%) Frame = +2 Query: 221 DYNVLVMDLLGPSLEDLFNFCSRKLSL--KTVLMLADQMINRVEFVHSKSFLHRDIKPDN 394 +Y L+M+L S +LF+ S K + Q+ + + ++HS + +HRD+KP+N Sbjct: 139 NYIYLIMELC--SGRELFDSIIENGSFTEKNAATIMKQIFSAIFYLHSLNIVHRDLKPEN 196 Query: 395 FLMGLGRRANQVYVIDFGLAKKY---RDTSTHQHIPY 496 FL + + + +IDFGL+K T+T PY Sbjct: 197 FLFQSENKDSLLKIIDFGLSKNLGTGEFTTTKAGTPY 233
>KC61_SCHPO (Q9UU87) Probable serine/threonine-protein kinase C1919.01 (EC| 2.7.11.1) Length = 354 Score = 46.2 bits (108), Expect = 8e-05 Identities = 23/55 (41%), Positives = 33/55 (60%) Frame = +2 Query: 293 LSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAK 457 + L+T Q++ V ++H K +HRDIKPDN L + N + VIDFGLA+ Sbjct: 172 MPLETCRKSFRQLVLAVNYIHGKGVIHRDIKPDNILF---KENNNLCVIDFGLAE 223
>CCRK_MACMU (Q5EDC3) Cell cycle-related kinase (EC 2.7.11.22)| (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) Length = 243 Score = 46.2 bits (108), Expect = 8e-05 Identities = 33/138 (23%), Positives = 63/138 (45%), Gaps = 4/138 (2%) Frame = +2 Query: 62 IYLGTNIQTNEEVGIK---LENVKTKHP-QLLYESKIYRILQGGTGIPNVRWFGVEGDYN 229 ++ +++T E V +K L ++ P Q L E K + + + ++ G Sbjct: 18 VFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMGDNQYVVQLKAVFPHGGGF 77 Query: 230 VLVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGL 409 VL + + L ++ R L+ V ++ V F H+ + +HRD+KP N L+ Sbjct: 78 VLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHANNIVHRDLKPANLLIS- 136 Query: 410 GRRANQVYVIDFGLAKKY 463 + Q+ + DFGLA+ + Sbjct: 137 --ASGQLKIADFGLARVF 152
>CSK2A_THEPA (P28547) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II)| Length = 348 Score = 46.2 bits (108), Expect = 8e-05 Identities = 38/137 (27%), Positives = 70/137 (51%), Gaps = 2/137 (1%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIK-LENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVL 235 E++ G N T ++ IK L+ VK K ++ E KI + L+GG I ++ + D Sbjct: 68 EVFEGINTVTKDKCVIKILKPVKKK--KIKREIKILQNLRGGPNI--IKLLDIVKDPQSR 123 Query: 236 VMDLLGPSLEDL-FNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLG 412 L+ + + F LS++ + Q++ + + HS+ +HRDIKP N ++ Sbjct: 124 TPSLIFEHVNNTDFKTLYPTLSIQDIKYYIYQLLKAMNYCHSQGIMHRDIKPHNVMIDHE 183 Query: 413 RRANQVYVIDFGLAKKY 463 ++ + +ID+GLA+ Y Sbjct: 184 KKI--LRLIDWGLAEFY 198
>CSK22_CHICK (P21869) Casein kinase II subunit alpha' (EC 2.7.11.1) (CK II)| Length = 350 Score = 46.2 bits (108), Expect = 8e-05 Identities = 39/144 (27%), Positives = 70/144 (48%), Gaps = 9/144 (6%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIK-LENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVL 235 E++ NI NE V +K L+ VK K ++ E KI L+GGT I N+ Sbjct: 53 EVFEAINITNNERVVVKILKPVKKK--KIKREVKILENLRGGTNIINLI---------DT 101 Query: 236 VMDLLGPSLEDLFNFCSRKLSLKTVLMLAD--------QMINRVEFVHSKSFLHRDIKPD 391 V D + + +F + + + +L D +++ +++ HS +HRD+KP Sbjct: 102 VKDPVSKTPALVFEYINNTDFKQLYQILTDFDIRFYMYELLKALDYCHSMGIMHRDVKPH 161 Query: 392 NFLMGLGRRANQVYVIDFGLAKKY 463 N + + + ++ +ID+GLA+ Y Sbjct: 162 NVM--IDHQQKKLRLIDWGLAEFY 183
>PRKX_MOUSE (Q922R0) Serine/threonine-protein kinase PRKX (EC 2.7.11.1)| (PKA-related protein kinase) Length = 355 Score = 45.8 bits (107), Expect = 1e-04 Identities = 25/91 (27%), Positives = 49/91 (53%), Gaps = 2/91 (2%) Frame = +2 Query: 203 WFGVEGDYNVLVMDLLGPSLEDLFNFCSRKLSLKTV--LMLADQMINRVEFVHSKSFLHR 376 W G + + ++M+ + +LF + + +V + A +++ +E++HSK ++R Sbjct: 111 WTGHDNRFLYMLMEFVPGG--ELFTYLRNRGRFSSVASVFYATEIVCAIEYLHSKEIVYR 168 Query: 377 DIKPDNFLMGLGRRANQVYVIDFGLAKKYRD 469 D+KP+N L+ R + + DFG AKK D Sbjct: 169 DLKPENILLD---REGHIKLTDFGFAKKLVD 196
>AURKC_HUMAN (Q9UQB9) Serine/threonine-protein kinase 13 (EC 2.7.11.1)| (Aurora/Ipl1/Eg2 protein 2) (Aurora/Ipl1-related kinase 3) (Aurora-C) Length = 309 Score = 45.8 bits (107), Expect = 1e-04 Identities = 31/109 (28%), Positives = 48/109 (44%) Frame = +2 Query: 284 SRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKY 463 S KL + + +++ + + + H K +HRDIKP+N L+G +V + DFG + Sbjct: 135 SEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGF---RGEVKIADFGWS--- 188 Query: 464 RDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGYVLMY 610 H P K + GT Y G + DL +G VL Y Sbjct: 189 ------VHTPSLRRKTMCGTLDYLPPEMIEGRTYDEKVDLWCIG-VLCY 230
>PAK3_RAT (Q62829) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) (Beta-PAK) (p65-PAK) Length = 544 Score = 45.8 bits (107), Expect = 1e-04 Identities = 37/131 (28%), Positives = 64/131 (48%), Gaps = 2/131 (1%) Frame = +2 Query: 62 IYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQG-GTGIPNVRWFGVEGDYNVLV 238 +Y +I T +EV IK N++ + + L ++I + + I N + GD +V Sbjct: 282 VYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVV 341 Query: 239 MDLL-GPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGR 415 M+ L G SL D+ + + + + + ++F+HS +HRDIK DN L+G+ Sbjct: 342 MEYLAGGSLTDVVT--ETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMD- 398 Query: 416 RANQVYVIDFG 448 V + DFG Sbjct: 399 --GSVKLTDFG 407
>PCTK1_MOUSE (Q04735) Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 1) (CRK5) Length = 496 Score = 45.8 bits (107), Expect = 1e-04 Identities = 29/107 (27%), Positives = 53/107 (49%), Gaps = 5/107 (4%) Frame = +2 Query: 233 LVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLG 412 LV + L L+ + C +++ V + Q++ + + H + LHRD+KP N L+ Sbjct: 238 LVFEYLDKDLKQYLDDCGNVINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLI--- 294 Query: 413 RRANQVYVIDFGLAK-KYRDTSTHQH----IPYRENKNLTGTARYAS 538 ++ + DFGLA+ K T T+ + + YR L G+ Y++ Sbjct: 295 NERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYST 341
>BRSK1_HUMAN (Q8TDC3) BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1| kinase) (SAD1A) Length = 794 Score = 45.8 bits (107), Expect = 1e-04 Identities = 49/189 (25%), Positives = 85/189 (44%), Gaps = 8/189 (4%) Frame = +2 Query: 62 IYLGTNIQTNEEVGIKLENVKTKHPQLLY----ESKIYRILQGGTGIPNV-RWFGVEGDY 226 + LG + T ++V IK+ N + +L E I ++++ P+V + V + Sbjct: 64 VKLGVHCITGQKVAIKIVNREKLSESVLMKVEREIAILKLIEH----PHVLKLHDVYENK 119 Query: 227 NVLVMDLLGPSLEDLFNFCSRK--LSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFL 400 L + L S +LF++ +K L+ K Q+++ ++F HS S HRD+KP+N L Sbjct: 120 KYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLL 179 Query: 401 MGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIE-QSRRD 577 + N + + DFG+A S + G+ YA G + RR Sbjct: 180 LD---EKNNIRIADFGMASLQVGDSLLE--------TSCGSPHYACPEVIKGEKYDGRRA 228 Query: 578 DLESLGYVL 604 D+ S G +L Sbjct: 229 DMWSCGVIL 237
>MOS_MSVMO (P00538) Serine/threonine-protein kinase transforming protein mos| (EC 2.7.11.1) Length = 374 Score = 45.8 bits (107), Expect = 1e-04 Identities = 31/108 (28%), Positives = 53/108 (49%) Frame = +2 Query: 281 CSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKK 460 C ++LSL L + ++N + F+HS+S LH D+KP N L+ + + DFG ++K Sbjct: 197 CRKQLSLGKCLKYSLDVVNGLLFLHSQSILHLDLKPANILIS---EQDVCKISDFGCSQK 253 Query: 461 YRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGYVL 604 +D Q P ++ GT + + G + + D+ S G L Sbjct: 254 LQDLRGRQASP----PHIGGTYTHQAPEILKGEIATPKADIYSFGITL 297
>E2AK1_HUMAN (Q9BQI3) Eukaryotic translation initiation factor 2-alpha kinase 1| (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Heme-controlled repressor) (HCR) (Hemin-sensitive initiation factor Length = 630 Score = 45.8 bits (107), Expect = 1e-04 Identities = 33/100 (33%), Positives = 50/100 (50%), Gaps = 6/100 (6%) Frame = +2 Query: 326 QMINRVEFVHSKSFLHRDIKPDN-FLMGLGRRANQVYVIDFGLA-----KKYRDTSTHQH 487 +++ V ++H+ +HRD+KP N FL G + QV + DFGLA +K D + Sbjct: 425 ELVEGVFYIHNMGIVHRDLKPRNIFLHGPDQ---QVKIGDFGLACTDILQKNTDWTNRNG 481 Query: 488 IPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGYVLM 607 + + GT YAS G E + D+ SLG VL+ Sbjct: 482 KRTPTHTSRVGTCLYASPEQLEGSEYDAKSDMYSLGVVLL 521
>CRK_DAUCA (P53681) CDPK-related protein kinase (EC 2.7.11.1) (PK421)| Length = 602 Score = 45.8 bits (107), Expect = 1e-04 Identities = 45/154 (29%), Positives = 70/154 (45%), Gaps = 3/154 (1%) Frame = +2 Query: 149 ESKIYRILQGGTGIPNVRWFGVEGDY-NVLVMDLLGPSLEDLFNFCSR--KLSLKTVLML 319 E KI R L G + V+++ D+ NV V+ L E L SR K + + Sbjct: 199 EVKILRALTGHNNL--VQFYDAFEDHTNVYVVMELCEGGELLDRILSRGGKYTEDDAKAV 256 Query: 320 ADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYR 499 Q++N V F H + +HRD+KP+NFL +Q+ IDFGL+ + P Sbjct: 257 MIQILNVVAFCHLQGVVHRDLKPENFLFKSKDEDSQLKAIDFGLSDYVK--------PDE 308 Query: 500 ENKNLTGTARYASVNTHLGIEQSRRDDLESLGYV 601 ++ G+A Y + L S D+ S+G + Sbjct: 309 RLNDIVGSAYYVAPEV-LHRSYSTEADVWSIGVI 341
>PAK3_PONPY (Q7YQL3) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) Length = 559 Score = 45.8 bits (107), Expect = 1e-04 Identities = 37/131 (28%), Positives = 64/131 (48%), Gaps = 2/131 (1%) Frame = +2 Query: 62 IYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQG-GTGIPNVRWFGVEGDYNVLV 238 +Y +I T +EV IK N++ + + L ++I + + I N + GD +V Sbjct: 297 VYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVV 356 Query: 239 MDLL-GPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGR 415 M+ L G SL D+ + + + + + ++F+HS +HRDIK DN L+G+ Sbjct: 357 MEYLAGGSLTDVVT--ETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMD- 413 Query: 416 RANQVYVIDFG 448 V + DFG Sbjct: 414 --GSVKLTDFG 422
>PAK3_PANTR (Q7YQL4) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) Length = 559 Score = 45.8 bits (107), Expect = 1e-04 Identities = 37/131 (28%), Positives = 64/131 (48%), Gaps = 2/131 (1%) Frame = +2 Query: 62 IYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQG-GTGIPNVRWFGVEGDYNVLV 238 +Y +I T +EV IK N++ + + L ++I + + I N + GD +V Sbjct: 297 VYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVV 356 Query: 239 MDLL-GPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGR 415 M+ L G SL D+ + + + + + ++F+HS +HRDIK DN L+G+ Sbjct: 357 MEYLAGGSLTDVVT--ETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMD- 413 Query: 416 RANQVYVIDFG 448 V + DFG Sbjct: 414 --GSVKLTDFG 422
>PAK3_MOUSE (Q61036) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) (Beta-PAK) (CDC42/RAC effector kinase PAK-B) Length = 559 Score = 45.8 bits (107), Expect = 1e-04 Identities = 37/131 (28%), Positives = 64/131 (48%), Gaps = 2/131 (1%) Frame = +2 Query: 62 IYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQG-GTGIPNVRWFGVEGDYNVLV 238 +Y +I T +EV IK N++ + + L ++I + + I N + GD +V Sbjct: 297 VYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVV 356 Query: 239 MDLL-GPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGR 415 M+ L G SL D+ + + + + + ++F+HS +HRDIK DN L+G+ Sbjct: 357 MEYLAGGSLTDVVT--ETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMD- 413 Query: 416 RANQVYVIDFG 448 V + DFG Sbjct: 414 --GSVKLTDFG 422
>PAK3_HUMAN (O75914) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) (Beta-PAK) (Oligophrenin-3) Length = 559 Score = 45.8 bits (107), Expect = 1e-04 Identities = 37/131 (28%), Positives = 64/131 (48%), Gaps = 2/131 (1%) Frame = +2 Query: 62 IYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQG-GTGIPNVRWFGVEGDYNVLV 238 +Y +I T +EV IK N++ + + L ++I + + I N + GD +V Sbjct: 297 VYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVV 356 Query: 239 MDLL-GPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGR 415 M+ L G SL D+ + + + + + ++F+HS +HRDIK DN L+G+ Sbjct: 357 MEYLAGGSLTDVVT--ETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMD- 413 Query: 416 RANQVYVIDFG 448 V + DFG Sbjct: 414 --GSVKLTDFG 422
>NEK1_CAEEL (P84199) Serine/threonine-protein kinase D1044.8 (EC 2.7.11.1)| Length = 959 Score = 45.8 bits (107), Expect = 1e-04 Identities = 37/112 (33%), Positives = 54/112 (48%), Gaps = 5/112 (4%) Frame = +2 Query: 140 LLYESKIYRILQGGTGIPNVRWFGVEGDYNVLVMDLL-GPSLEDLFNFCSRK---LSLKT 307 ++ E KI + I R VE +VMDL+ G SL DL K K Sbjct: 485 MISEVKIIKQQLRHPNIVRYRRIFVENHRLYIVMDLIQGCSLRDLIITMKEKKGNFEEKK 544 Query: 308 VLMLADQMINRVEFVHS-KSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKK 460 + + QM+ + ++H K +HRD+KP+N +M R V + DFGLAK+ Sbjct: 545 IWAMVVQMMLALRYLHKEKQIVHRDLKPNNIMMTTDER---VVITDFGLAKQ 593
>CDC22_MEDSA (Q05006) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| Length = 294 Score = 45.8 bits (107), Expect = 1e-04 Identities = 28/84 (33%), Positives = 46/84 (54%), Gaps = 5/84 (5%) Frame = +2 Query: 302 KTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYR---DT 472 + + M Q++ + + HS LHRD+KP N L + R +N V + DFGLA+ + T Sbjct: 102 RQIKMFLYQILCGIAYCHSHRVLHRDLKPQNLL--IDRSSNAVKLADFGLARAFGIPVRT 159 Query: 473 STHQHIP--YRENKNLTGTARYAS 538 TH+ + YR + L G+ Y++ Sbjct: 160 FTHEVVTLWYRAPEILLGSRHYST 183
>CSK22_ARATH (Q08466) Casein kinase II subunit alpha-2 (EC 2.7.11.1) (CK II)| Length = 333 Score = 45.8 bits (107), Expect = 1e-04 Identities = 39/137 (28%), Positives = 68/137 (49%), Gaps = 2/137 (1%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIK-LENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVL 235 E++ G N+ NE+ IK L+ VK K ++ E KI + L GG I V+ V D + Sbjct: 47 EVFEGINMNNNEKCIIKILKPVKKK--KIRREIKILQNLCGGPNI--VKLLDVVRDQHSK 102 Query: 236 VMDLLGPSLEDL-FNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLG 412 L+ + F L+ + +++ ++F HS+ +HRD+KP N + + Sbjct: 103 TPSLIFEYVNSTDFKVLYPTLTDYDIRYYIYELLKALDFCHSQGIMHRDVKPHNVM--ID 160 Query: 413 RRANQVYVIDFGLAKKY 463 ++ +ID+GLA+ Y Sbjct: 161 HELRKLRLIDWGLAEFY 177
>DAPK3_RAT (O88764) Death-associated protein kinase 3 (EC 2.7.11.1) (DAP| kinase 3) (DAP-like kinase) (Dlk) (ZIP-kinase) Length = 448 Score = 45.4 bits (106), Expect = 1e-04 Identities = 39/131 (29%), Positives = 67/131 (51%), Gaps = 7/131 (5%) Frame = +2 Query: 230 VLVMDLLGPSLEDLFNFCSRKLSLKT--VLMLADQMINRVEFVHSKSFLHRDIKPDN-FL 400 VL+++L+ +LF+F + K SL Q+++ V ++HSK H D+KP+N L Sbjct: 90 VLILELVSGG--ELFDFLAEKESLTEDEATQFLKQILDGVHYLHSKRIAHFDLKPENIML 147 Query: 401 MGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYAS---VNTH-LGIEQS 568 + + ++ +IDFG+A + S E KN+ GT + + VN LG+E Sbjct: 148 LDKHAASPRIKLIDFGIAHRIEAGS--------EFKNIFGTPEFVAPEIVNYEPLGLEA- 198 Query: 569 RRDDLESLGYV 601 D+ S+G + Sbjct: 199 ---DMWSIGVI 206
>DAPK3_MOUSE (O54784) Death-associated protein kinase 3 (EC 2.7.11.1) (DAP| kinase 3) (DAP-like kinase) (Dlk) (ZIP-kinase) Length = 448 Score = 45.4 bits (106), Expect = 1e-04 Identities = 39/131 (29%), Positives = 67/131 (51%), Gaps = 7/131 (5%) Frame = +2 Query: 230 VLVMDLLGPSLEDLFNFCSRKLSLKT--VLMLADQMINRVEFVHSKSFLHRDIKPDN-FL 400 VL+++L+ +LF+F + K SL Q+++ V ++HSK H D+KP+N L Sbjct: 90 VLILELVSGG--ELFDFLAEKESLTEDEATQFLKQILDGVHYLHSKRIAHFDLKPENIML 147 Query: 401 MGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYAS---VNTH-LGIEQS 568 + + ++ +IDFG+A + S E KN+ GT + + VN LG+E Sbjct: 148 LDKHAASPRIKLIDFGIAHRIEAGS--------EFKNIFGTPEFVAPEIVNYEPLGLEA- 198 Query: 569 RRDDLESLGYV 601 D+ S+G + Sbjct: 199 ---DMWSIGVI 206
>PK1_ASFB7 (P42493) Serine/threonine-protein kinase (EC 2.7.11.1)| Length = 298 Score = 45.4 bits (106), Expect = 1e-04 Identities = 30/125 (24%), Positives = 61/125 (48%) Frame = +2 Query: 158 IYRILQGGTGIPNVRWFGVEGDYNVLVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMIN 337 + + LQ G+ + + Y++L+++ + S++ L +KL + Q+I Sbjct: 79 VLKALQDTPGVIKLIEYTENAMYHILIIEYIPNSVDLLHYHYFKKLEETEAKKIIFQLIL 138 Query: 338 RVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLT 517 ++ ++ K F+H DIK +N ++ + ++ + VIDFG A + +T R N+ Sbjct: 139 IIQNIYEKGFIHGDIKDENLIIDINQKI--IKVIDFGSAVRLDET--------RPQYNMF 188 Query: 518 GTARY 532 GT Y Sbjct: 189 GTWEY 193
>TAOK3_PONPY (Q5R4F3) Serine/threonine-protein kinase TAO3 (EC 2.7.11.1)| (Thousand and one amino acid protein 3) Length = 898 Score = 45.4 bits (106), Expect = 1e-04 Identities = 40/150 (26%), Positives = 62/150 (41%), Gaps = 5/150 (3%) Frame = +2 Query: 62 IYLGTNIQTNEEVGIKL-----ENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDY 226 +Y TN TNE V IK + K +L E K R L+ I + ++ Sbjct: 38 VYFATNAHTNEVVAIKKMSYSGKQTHEKWQDILKEVKFLRQLKHPNTIEYKGCY-LKEHT 96 Query: 227 NVLVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMG 406 LVM+ S DL + L + + ++ + ++HS + +HRDIK N L+ Sbjct: 97 AWLVMEYCLGSASDLLEVHKKPLQEVEIAAITHGALHGLAYLHSHALIHRDIKAGNILL- 155 Query: 407 LGRRANQVYVIDFGLAKKYRDTSTHQHIPY 496 QV + DFG A ++ PY Sbjct: 156 --TEPGQVKLADFGSASVASPANSFVGTPY 183
>PKSC_STRCO (Q9S2C0) Serine/threonine protein kinase pksC (EC 2.7.11.1)| Length = 556 Score = 45.4 bits (106), Expect = 1e-04 Identities = 30/98 (30%), Positives = 46/98 (46%) Frame = +2 Query: 311 LMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYRDTSTHQHI 490 L + ++ +E H +HRDIKP N +M + V V+DFG+A+ + T Sbjct: 129 LKITADVLAALEISHEMGLVHRDIKPGNVMM---TKRGVVKVMDFGIARAMQSGVTSM-- 183 Query: 491 PYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGYVL 604 + + GT +Y S LG R DL S+G +L Sbjct: 184 --TQTGMVVGTPQYLSPEQALGRGVDARSDLYSVGIML 219
>WIS4_SCHPO (O14299) MAP kinase kinase kinase wis4 (EC 2.7.11.25) (MAP kinase| kinase kinase wak1) (MAP kinase kinase kinase wik1) Length = 1401 Score = 45.4 bits (106), Expect = 1e-04 Identities = 51/196 (26%), Positives = 89/196 (45%), Gaps = 13/196 (6%) Frame = +2 Query: 59 EIYLGTNIQTNEEVG---IKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYN 229 ++Y G N++T + + IKL++ +T + +L+ V ++GVE Sbjct: 1050 DVYTGVNMETGDLLAVKEIKLQDSRTFRSTVDQIHNEMTVLERLNHPNVVTYYGVEVHRE 1109 Query: 230 VLVMDL---LGPSLEDLFNFCSRKLSLKTVLML-ADQMINRVEFVHSKSFLHRDIKPDNF 397 + + + G SL DL ++ + VL + Q++ + ++HS+ LHRDIKP N Sbjct: 1110 KVYIFMEFCQGGSLADLL--AHGRIEDENVLKVYVVQLLEGLAYIHSQHILHRDIKPANI 1167 Query: 398 LMGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYR----ENKNLTGTARYASVNTHLGIEQ 565 L+ + DFG A Y T + Y E ++L GT Y + LG ++ Sbjct: 1168 LLD---HRGMIKYSDFGSA-LYVSPPTDPEVRYEDIQPELQHLAGTPMYMAPEIILGTKK 1223 Query: 566 S--RRDDLESLGYVLM 607 D+ SLG V++ Sbjct: 1224 GDFGAMDIWSLGCVIL 1239
>MKNK2_XENLA (Q6P431) MAP kinase-interacting serine/threonine-protein kinase 2| (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (Mnk2) Length = 467 Score = 45.4 bits (106), Expect = 1e-04 Identities = 43/185 (23%), Positives = 77/185 (41%), Gaps = 9/185 (4%) Frame = +2 Query: 77 NIQTNEEVGIKLENVKTKHPQ--LLYESKIYRILQGGTGIPNVRWFGVEGDYNVLVMDLL 250 N+ TN+E +K+ + H + + E ++ QG + + + F E D LV + + Sbjct: 102 NLITNKEYAVKIIEKRPGHSRSRVFREVEMLYQCQGHSNVLELIEFFEEEDKFYLVFEKM 161 Query: 251 --GPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRAN 424 G L + R + + + + + ++H+K HRD+KP+N L + + Sbjct: 162 CGGSILNHIHR--RRHFNEREASFVVRDIAEALNYLHNKGIAHRDLKPENILCESPHQVS 219 Query: 425 QVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQ-----SRRDDLES 589 V + DF L + S I E G+A Y + + +R DL S Sbjct: 220 PVKICDFDLGSGIKLNSDCSPISTPELLTPCGSAEYMAPEVVEAFNEEASIYDKRCDLWS 279 Query: 590 LGYVL 604 LG +L Sbjct: 280 LGVIL 284
>BRSK2_HUMAN (Q8IWQ3) BR serine/threonine-protein kinase 2 (EC 2.7.11.1)| (Serine/threonine-protein kinase 29) (SAD1B) Length = 736 Score = 45.4 bits (106), Expect = 1e-04 Identities = 39/138 (28%), Positives = 69/138 (50%), Gaps = 7/138 (5%) Frame = +2 Query: 62 IYLGTNIQTNEEVGIKLENVKTKHPQLLY----ESKIYRILQGGTGIPNV-RWFGVEGDY 226 + LG + T ++V IK+ N + +L E I ++++ P+V + V + Sbjct: 33 VKLGVHCVTCQKVAIKIVNREKLSESVLMKVEREIAILKLIEH----PHVLKLHDVYENK 88 Query: 227 NVLVMDLLGPSLEDLFNFCSRK--LSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFL 400 L + L S +LF++ +K L+ K Q+I+ ++F HS S HRD+KP+N L Sbjct: 89 KYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLL 148 Query: 401 MGLGRRANQVYVIDFGLA 454 + N + + DFG+A Sbjct: 149 LD---EKNNIRIADFGMA 163
>CSK2A_MAIZE (P28523) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II)| (CK2-alpha) Length = 332 Score = 45.4 bits (106), Expect = 1e-04 Identities = 37/137 (27%), Positives = 69/137 (50%), Gaps = 2/137 (1%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIK-LENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVL 235 E++ G N+ NE+ IK L+ VK K ++ E KI + L GG I V+ + D + Sbjct: 47 EVFEGINVNNNEKCIIKILKPVKKK--KIKREIKILQNLCGGPNI--VKLLDIVRDQHSK 102 Query: 236 VMDLLGPSLEDL-FNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLG 412 L+ + + F L+ + +++ +++ HS+ +HRD+KP N + + Sbjct: 103 TPSLIFEYVNNTDFKVLYPTLTDYDIRYYIYELLKALDYCHSQGIMHRDVKPHNVM--ID 160 Query: 413 RRANQVYVIDFGLAKKY 463 ++ +ID+GLA+ Y Sbjct: 161 HELRKLRLIDWGLAEFY 177
>E2AK1_RAT (Q63185) Eukaryotic translation initiation factor 2-alpha kinase 1| (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Heme-controlled repressor) (HCR) (Hemin-sensitive initiation factor 2- Length = 620 Score = 45.4 bits (106), Expect = 1e-04 Identities = 32/100 (32%), Positives = 50/100 (50%), Gaps = 6/100 (6%) Frame = +2 Query: 326 QMINRVEFVHSKSFLHRDIKPDN-FLMGLGRRANQVYVIDFGLA-----KKYRDTSTHQH 487 +++ V ++H+ +HRD+KP N FL G + QV + DFGLA +K D + Sbjct: 423 ELVEGVFYIHNMGIVHRDLKPRNIFLHGPDQ---QVKIGDFGLACADIIQKSADWTNRNG 479 Query: 488 IPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGYVLM 607 + + GT YAS G E + D+ SLG +L+ Sbjct: 480 KGTPTHTSRVGTCLYASPEQLEGSEYDAKSDMYSLGVILL 519
>PCTK1_HUMAN (Q00536) Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 1) Length = 496 Score = 45.4 bits (106), Expect = 1e-04 Identities = 29/107 (27%), Positives = 53/107 (49%), Gaps = 5/107 (4%) Frame = +2 Query: 233 LVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLG 412 LV + L L+ + C +++ V + Q++ + + H + LHRD+KP N L+ Sbjct: 238 LVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLI--- 294 Query: 413 RRANQVYVIDFGLAK-KYRDTSTHQH----IPYRENKNLTGTARYAS 538 ++ + DFGLA+ K T T+ + + YR L G+ Y++ Sbjct: 295 NERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYST 341
>CDC2C_DROME (P23573) Cell division control protein 2 cognate (EC 2.7.11.22) (EC| 2.7.11.23) Length = 314 Score = 45.4 bits (106), Expect = 1e-04 Identities = 30/114 (26%), Positives = 56/114 (49%), Gaps = 5/114 (4%) Frame = +2 Query: 212 VEGDYNVLVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPD 391 + G+ ++ + L L+ L + + + + Q+++ V F H+ LHRD+KP Sbjct: 75 ISGNNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLKPQ 134 Query: 392 NFLMGLGRRANQVYVIDFGLAKKYR---DTSTHQHIP--YRENKNLTGTARYAS 538 N L+ A ++ + DFGLA+ + TH+ + YR + L GT Y++ Sbjct: 135 NLLVD---TAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYST 185
>MKNK2_XENTR (Q66I46) MAP kinase-interacting serine/threonine-protein kinase 2| (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (Mnk2) Length = 466 Score = 45.4 bits (106), Expect = 1e-04 Identities = 43/185 (23%), Positives = 77/185 (41%), Gaps = 9/185 (4%) Frame = +2 Query: 77 NIQTNEEVGIKLENVKTKHPQ--LLYESKIYRILQGGTGIPNVRWFGVEGDYNVLVMDLL 250 N+ TN+E +K+ + H + + E ++ QG + + + F E D LV + + Sbjct: 102 NLITNKEYAVKIIEKRPGHSRSRVFREVEMLYQCQGHSNVLELIEFFEEEDKFYLVFEKM 161 Query: 251 --GPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRAN 424 G L + R + + + + + ++H+K HRD+KP+N L + + Sbjct: 162 CGGSILNHIHR--RRHFNEREASFVVRDIAEALNYLHNKGIAHRDLKPENILCESPHQVS 219 Query: 425 QVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQ-----SRRDDLES 589 V + DF L + S I E G+A Y + + +R DL S Sbjct: 220 PVKICDFDLGSGIKLNSDCSPISTPELLTPCGSAEYMAPEVVEAFNEEASIYDKRCDLWS 279 Query: 590 LGYVL 604 LG +L Sbjct: 280 LGVIL 284
>CDC2_CHERU (P93101) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 45.1 bits (105), Expect = 2e-04 Identities = 26/76 (34%), Positives = 43/76 (56%), Gaps = 5/76 (6%) Frame = +2 Query: 326 QMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYR---DTSTHQHIP- 493 Q++ + + HS LHRD+KP N L + R+ N + + DFGLA+ + T TH+ + Sbjct: 110 QILRGIAYCHSHRVLHRDLKPQNLL--IDRQTNALKLADFGLARAFGIPVRTFTHEVVTL 167 Query: 494 -YRENKNLTGTARYAS 538 YR + L G+ Y++ Sbjct: 168 WYRAPEILLGSRHYST 183
>PRKX_HUMAN (P51817) Serine/threonine-protein kinase PRKX (EC 2.7.11.1)| (Protein kinase PKX1) Length = 358 Score = 45.1 bits (105), Expect = 2e-04 Identities = 24/70 (34%), Positives = 41/70 (58%), Gaps = 2/70 (2%) Frame = +2 Query: 266 DLFNFCSRK--LSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVI 439 +LF++ + S T L + ++I +E++HSK ++RD+KP+N L+ R + + Sbjct: 133 ELFSYLRNRGRFSSTTGLFYSAEIICAIEYLHSKEIVYRDLKPENILLD---RDGHIKLT 189 Query: 440 DFGLAKKYRD 469 DFG AKK D Sbjct: 190 DFGFAKKLVD 199
>STK6_RAT (P59241) Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Aurora-A)| (ratAurA) Length = 397 Score = 45.1 bits (105), Expect = 2e-04 Identities = 31/95 (32%), Positives = 43/95 (45%) Frame = +2 Query: 326 QMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYREN 505 ++ N + + HSK +HRDIKP+N L+G ++ + DFG + H P Sbjct: 232 ELANALSYCHSKRVIHRDIKPENLLLGSN---GELKIADFGWS---------VHAPSSRR 279 Query: 506 KNLTGTARYASVNTHLGIEQSRRDDLESLGYVLMY 610 L GT Y G + DL SLG VL Y Sbjct: 280 TTLCGTLDYQPPEMIEGRMHDEKVDLWSLG-VLCY 313
>PDK1A_XENLA (Q6NU47) Serine/threonine-protein kinase pdik1l-A (EC 2.7.11.1)| Length = 339 Score = 45.1 bits (105), Expect = 2e-04 Identities = 39/166 (23%), Positives = 73/166 (43%), Gaps = 27/166 (16%) Frame = +2 Query: 110 LENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLVMDLLGPSLED------- 268 L +++++HP +++ + +LQ + + + G +VL + L+ SL+ Sbjct: 57 LSSIQSQHPNVIHMEEC--VLQKDGMVQRM----LHGSSSVLYLPLVETSLKGEIAFDPR 110 Query: 269 -------LFNFC----------SRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNF 397 + +FC +R+ S +T Q+ + + F+H +HRD+KPDN Sbjct: 111 SIYCLWFVMDFCDGGDMNEYILTRRPSRRTNTSFMLQLSSALAFLHKNQIIHRDLKPDNI 170 Query: 398 LMGLGRRA---NQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTA 526 L+ R + V DFGL+K + + P NK+ TA Sbjct: 171 LVCKSRDGVDEPTLKVADFGLSKVCSSSGLNPEEPANVNKSFLSTA 216
>DAPK2_MOUSE (Q8VDF3) Death-associated protein kinase 2 (EC 2.7.11.1) (DAP| kinase 2) (DAP-kinase-related protein 1) (DRP-1) Length = 370 Score = 45.1 bits (105), Expect = 2e-04 Identities = 39/131 (29%), Positives = 67/131 (51%), Gaps = 7/131 (5%) Frame = +2 Query: 230 VLVMDLLGPSLEDLFNFCSRKLSL--KTVLMLADQMINRVEFVHSKSFLHRDIKPDN-FL 400 VL+++L+ +LF+F ++K SL + Q+++ V ++H+K H D+KP+N L Sbjct: 100 VLILELVSGG--ELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIML 157 Query: 401 MGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYAS---VNTH-LGIEQS 568 + + +IDFGLA + D E KN+ GT + + VN LG+E Sbjct: 158 LDKNIPIPHIKLIDFGLAHEIEDGV--------EFKNIFGTPEFVAPEIVNYEPLGLEA- 208 Query: 569 RRDDLESLGYV 601 D+ S+G + Sbjct: 209 ---DMWSIGVI 216
>DAPK2_HUMAN (Q9UIK4) Death-associated protein kinase 2 (EC 2.7.11.1) (DAP| kinase 2) (DAP-kinase-related protein 1) (DRP-1) Length = 370 Score = 45.1 bits (105), Expect = 2e-04 Identities = 39/131 (29%), Positives = 67/131 (51%), Gaps = 7/131 (5%) Frame = +2 Query: 230 VLVMDLLGPSLEDLFNFCSRKLSL--KTVLMLADQMINRVEFVHSKSFLHRDIKPDN-FL 400 VL+++L+ +LF+F ++K SL + Q+++ V ++H+K H D+KP+N L Sbjct: 100 VLILELVSGG--ELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIML 157 Query: 401 MGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYAS---VNTH-LGIEQS 568 + + +IDFGLA + D E KN+ GT + + VN LG+E Sbjct: 158 LDKNIPIPHIKLIDFGLAHEIEDGV--------EFKNIFGTPEFVAPEIVNYEPLGLEA- 208 Query: 569 RRDDLESLGYV 601 D+ S+G + Sbjct: 209 ---DMWSIGVI 216
>PDPK1_HUMAN (O15530) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (hPDK1) Length = 556 Score = 45.1 bits (105), Expect = 2e-04 Identities = 25/93 (26%), Positives = 44/93 (47%) Frame = +2 Query: 326 QMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYREN 505 ++++ +E++H K +HRD+KP+N L+ + + DFG AK S Sbjct: 188 EIVSALEYLHGKGIIHRDLKPENILL---NEDMHIQITDFGTAKVLSPESKQARA----- 239 Query: 506 KNLTGTARYASVNTHLGIEQSRRDDLESLGYVL 604 + GTA+Y S + DL +LG ++ Sbjct: 240 NSFVGTAQYVSPELLTEKSACKSSDLWALGCII 272
>NEK9_HUMAN (Q8TD19) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)| (NimA-related protein kinase 9) (Never in mitosis A-related kinase 9) (Nercc1 kinase) (NIMA-related kinase 8) (Nek8) Length = 979 Score = 45.1 bits (105), Expect = 2e-04 Identities = 28/93 (30%), Positives = 46/93 (49%) Frame = +2 Query: 326 QMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYREN 505 Q+++ V +H LHRDIK N + +AN + + D+GLAKK Y Sbjct: 159 QIVSAVSCIHKAGILHRDIKTLNIFL---TKANLIKLGDYGLAKKLNS-------EYSMA 208 Query: 506 KNLTGTARYASVNTHLGIEQSRRDDLESLGYVL 604 + L GT Y S G++ + + D+ ++G V+ Sbjct: 209 ETLVGTPYYMSPELCQGVKYNFKSDIWAVGCVI 241
>PKH1_YEAST (Q03407) Serine/threonine-protein kinase PKH1 (EC 2.7.11.1)| (3-phosphoinositide-dependent protein kinase 1) Length = 766 Score = 45.1 bits (105), Expect = 2e-04 Identities = 32/101 (31%), Positives = 51/101 (50%), Gaps = 6/101 (5%) Frame = +2 Query: 320 ADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAK--KYRDTSTHQHIP 493 A Q+I+ V+ +H+ +HRDIKP+N L+ + +V + DFG AK ++T P Sbjct: 230 ASQIIDAVDSLHNIGIIHRDIKPENILLD---KNMKVKLTDFGTAKILPEEPSNTADGKP 286 Query: 494 ----YRENKNLTGTARYASVNTHLGIEQSRRDDLESLGYVL 604 Y ++K+ GTA Y S R D+ + G +L Sbjct: 287 YFDLYAKSKSFVGTAEYVSPELLNDNYTDSRCDIWAFGCIL 327
>PRKY_HUMAN (O43930) Serine/threonine-protein kinase PRKY (EC 2.7.11.1)| Length = 277 Score = 45.1 bits (105), Expect = 2e-04 Identities = 24/70 (34%), Positives = 41/70 (58%), Gaps = 2/70 (2%) Frame = +2 Query: 266 DLFNFCSRK--LSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVI 439 +LF++ + S T L + ++I +E++HSK ++RD+KP+N L+ R + + Sbjct: 133 ELFSYLRNRGHFSSTTGLFYSAEIICAIEYLHSKEIVYRDLKPENILLD---RDGHIKLT 189 Query: 440 DFGLAKKYRD 469 DFG AKK D Sbjct: 190 DFGFAKKLVD 199
>PDK1L_MOUSE (Q8QZR7) Serine/threonine-protein kinase PDIK1L (EC 2.7.11.1)| (PDLIM1-interacting kinase 1-like) Length = 341 Score = 45.1 bits (105), Expect = 2e-04 Identities = 28/86 (32%), Positives = 40/86 (46%), Gaps = 5/86 (5%) Frame = +2 Query: 284 SRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQ-----VYVIDFG 448 SRK + KT Q+ + + F+H +HRD+KPDN L+ R + V DFG Sbjct: 133 SRKPNRKTNTSFMLQLSSALAFLHKNQIIHRDLKPDNILISQSRMDTSDLEPTLKVADFG 192 Query: 449 LAKKYRDTSTHQHIPYRENKNLTGTA 526 L+K + + P NK TA Sbjct: 193 LSKVCSASGQNPEEPVSVNKCFLSTA 218
>M3K8_HUMAN (P41279) Mitogen-activated protein kinase kinase kinase 8 (EC| 2.7.11.25) (COT proto-oncogene serine/threonine-protein kinase) (C-COT) (Cancer Osaka thyroid oncogene) Length = 467 Score = 45.1 bits (105), Expect = 2e-04 Identities = 45/185 (24%), Positives = 81/185 (43%), Gaps = 1/185 (0%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVLV 238 ++YL +I+T + + KL V P + +R V W G+ L Sbjct: 151 KVYLAQDIKTKKRMACKLIPVDQFKPSDVEIQACFRHENIAELYGAVLW----GETVHLF 206 Query: 239 MDL-LGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGR 415 M+ G S+ + C + ++ + ++ ++F+HSK +H DIKP N + Sbjct: 207 MEAGEGGSVLEKLESCGPMREFE-IIWVTKHVLKGLDFLHSKKVIHHDIKPSNIVF---- 261 Query: 416 RANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLG 595 + + ++DFGL+ + + + P K+L GT Y S L S + D+ SLG Sbjct: 262 MSTKAVLVDFGLSVQMTE---DVYFP----KDLRGTEIYMSPEVILCRGHSTKADIYSLG 314 Query: 596 YVLMY 610 L++ Sbjct: 315 ATLIH 319
>TAOK3_XENLA (Q6DD27) Serine/threonine-protein kinase TAO3 (EC 2.7.11.1)| (Thousand and one amino acid protein 3) Length = 896 Score = 45.1 bits (105), Expect = 2e-04 Identities = 38/150 (25%), Positives = 63/150 (42%), Gaps = 5/150 (3%) Frame = +2 Query: 62 IYLGTNIQTNEEVGIKL-----ENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDY 226 +Y TN TNE V +K + + K ++ E K + L+ I + ++ Sbjct: 38 VYFATNSTTNEIVAVKKMSYSGKQMNEKWQDIIKEVKFLQQLKHPNTIEYKGCY-LKDHT 96 Query: 227 NVLVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMG 406 LVM+ S DL + L + + + + ++HS + +HRDIK N L+ Sbjct: 97 AWLVMEYCLGSASDLLEVHKKPLQEVEIAAITHGALQGLAYLHSHNMIHRDIKAGNILL- 155 Query: 407 LGRRANQVYVIDFGLAKKYRDTSTHQHIPY 496 QV + DFG A K ++ PY Sbjct: 156 --TEPGQVKLADFGSASKSSPANSFVGTPY 183
>PDPK1_RAT (O55173) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (Protein kinase B kinase) (PkB kinase) Length = 559 Score = 45.1 bits (105), Expect = 2e-04 Identities = 25/93 (26%), Positives = 44/93 (47%) Frame = +2 Query: 326 QMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYREN 505 ++++ +E++H K +HRD+KP+N L+ + + DFG AK S Sbjct: 191 EIVSALEYLHGKGIIHRDLKPENILL---NEDMHIQITDFGTAKVLSPDSKQARA----- 242 Query: 506 KNLTGTARYASVNTHLGIEQSRRDDLESLGYVL 604 + GTA+Y S + DL +LG ++ Sbjct: 243 NSFVGTAQYVSPELLTEKSACKSSDLWALGCII 275
>PDPK1_MOUSE (Q9Z2A0) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (mPDK1) Length = 559 Score = 45.1 bits (105), Expect = 2e-04 Identities = 25/93 (26%), Positives = 44/93 (47%) Frame = +2 Query: 326 QMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYREN 505 ++++ +E++H K +HRD+KP+N L+ + + DFG AK S Sbjct: 191 EIVSALEYLHGKGIIHRDLKPENILL---NEDMHIQITDFGTAKVLSPESKQARA----- 242 Query: 506 KNLTGTARYASVNTHLGIEQSRRDDLESLGYVL 604 + GTA+Y S + DL +LG ++ Sbjct: 243 NSFVGTAQYVSPELLTEKSACKSSDLWALGCII 275
>CHK1_DROME (O61661) Serine/threonine-protein kinase grp (EC 2.7.11.1) (Protein| grapes) (Chk1 homolog) Length = 512 Score = 45.1 bits (105), Expect = 2e-04 Identities = 47/189 (24%), Positives = 85/189 (44%), Gaps = 6/189 (3%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIKLENVKTKHPQ----LLYESKIYRILQGGTGIPNVRWFGVEGDY 226 E+ L N QT E V +K+ ++K KHP + E I ++LQ + R+FG Sbjct: 35 EVKLLINRQTGEAVAMKMVDLK-KHPDAANSVRKEVCIQKMLQDKHIL---RFFGKRSQG 90 Query: 227 NVLVMDLLGPSLEDLFNFCSRKLSLKT--VLMLADQMINRVEFVHSKSFLHRDIKPDNFL 400 +V + L + +LF+ + + Q+++ + ++H + HRD+KP+N L Sbjct: 91 SVEYIFLEYAAGGELFDRIEPDVGMPQHEAQRYFTQLLSGLNYLHQRGIAHRDLKPENLL 150 Query: 401 MGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDD 580 + + V + DFG+A +R + + R GT Y + ++ D Sbjct: 151 LD---EHDNVKISDFGMATMFRCKGKERLLDKR-----CGTLPYVAPEVLQKAYHAQPAD 202 Query: 581 LESLGYVLM 607 L S G +L+ Sbjct: 203 LWSCGVILV 211
>NEK9_MOUSE (Q8K1R7) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)| (NimA-related protein kinase 9) (Never in mitosis A-related kinase 9) Length = 984 Score = 45.1 bits (105), Expect = 2e-04 Identities = 28/93 (30%), Positives = 46/93 (49%) Frame = +2 Query: 326 QMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYREN 505 Q+++ V +H LHRDIK N + +AN + + D+GLAKK Y Sbjct: 159 QIVSAVSCIHKAGILHRDIKTLNIFL---TKANLIKLGDYGLAKKLNS-------EYSMA 208 Query: 506 KNLTGTARYASVNTHLGIEQSRRDDLESLGYVL 604 + L GT Y S G++ + + D+ ++G V+ Sbjct: 209 ETLVGTPYYMSPELCQGVKYNFKSDIWAVGCVI 241
>BUR1_YARLI (Q6C842) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 706 Score = 45.1 bits (105), Expect = 2e-04 Identities = 44/164 (26%), Positives = 70/164 (42%), Gaps = 11/164 (6%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIK---LENVKTKHP-QLLYESKIYRILQGGTGIPNVRWFGVEGDY 226 E++ I T V +K L + K P L E +I ++L+ IP V GD Sbjct: 51 EVFRAEQITTKRHVALKKILLHSEKEGFPVTALREIRILKLLRHENVIPLVDLAVERGDQ 110 Query: 227 N-------VLVMDLLGPSLEDLFNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIK 385 + +V + L L S +LS + Q++ + ++H+K FLHRDIK Sbjct: 111 SKKERGCVYMVTPYMDHDLAGLLGNQSVQLSPAHIKCYMLQLLEGIGYLHAKKFLHRDIK 170 Query: 386 PDNFLMGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYRENKNLT 517 N L+ + + DFGLA+ Y + + +NLT Sbjct: 171 AANILV---NDQGILKLADFGLARGYDGPAPNSQTAGVNTENLT 211
>KDC2_DROME (P16912) Protein kinase DC2 (EC 2.7.11.1)| Length = 583 Score = 45.1 bits (105), Expect = 2e-04 Identities = 21/60 (35%), Positives = 37/60 (61%) Frame = +2 Query: 290 KLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYRD 469 K + +T A ++++ +E++HS ++RD+KP+N L+ R + + DFG AKK RD Sbjct: 368 KFTSQTSNFYAAEIVSALEYLHSLQIVYRDLKPENLLI---NRDGHLKITDFGFAKKLRD 424
>CSK2A_THEAN (Q4U925) Casein kinase II subunit alpha (EC 2.7.11.1) (CK II)| (TaCKIIalpha) Length = 348 Score = 45.1 bits (105), Expect = 2e-04 Identities = 37/137 (27%), Positives = 70/137 (51%), Gaps = 2/137 (1%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIK-LENVKTKHPQLLYESKIYRILQGGTGIPNVRWFGVEGDYNVL 235 E++ G N T ++ IK L+ VK K ++ E KI + L+GG I ++ + D Sbjct: 68 EVFEGLNTVTKDKCVIKILKPVKKK--KIKREIKILQNLRGGPNI--IKLLDIVKDPQSR 123 Query: 236 VMDLLGPSLEDL-FNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLG 412 L+ + + F L+++ + Q++ + + HS+ +HRDIKP N ++ Sbjct: 124 TPSLIFEHVNNTDFKTLYPTLTIQDIKYYIYQLLKAMNYCHSQGIMHRDIKPHNVMIDHE 183 Query: 413 RRANQVYVIDFGLAKKY 463 ++ + +ID+GLA+ Y Sbjct: 184 KKI--LRLIDWGLAEFY 198
>CDC21_PEA (P19026) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (p34) (Fragment) Length = 148 Score = 44.7 bits (104), Expect = 2e-04 Identities = 23/54 (42%), Positives = 32/54 (59%) Frame = +2 Query: 302 KTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKY 463 + V M QM+ + + HS LHRD+KP N L + RR N V + DFGLA+ + Sbjct: 86 RQVKMFLYQMLCGIAYCHSHRVLHRDLKPQNLL--IDRRTNCVKLADFGLARAF 137
>PKH3_ASHGO (Q753D9) Serine/threonine-protein kinase PKH3 (EC 2.7.11.1)| Length = 726 Score = 44.7 bits (104), Expect = 2e-04 Identities = 27/96 (28%), Positives = 47/96 (48%) Frame = +2 Query: 326 QMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYRDTSTHQHIPYREN 505 Q+++ VE++HS +HRD+KP+N L+ + ++ + DFG A + + Sbjct: 119 QLVDTVEYIHSMGVIHRDLKPENVLLD---KEGRLMIADFGAAYTVGQSDAGSD-GDKPA 174 Query: 506 KNLTGTARYASVNTHLGIEQSRRDDLESLGYVLMYF 613 + GTA Y S L + D+ +LG +L F Sbjct: 175 TSFVGTAEYVSPELLLENKSYYSSDVWALGCMLYQF 210
>PK1_NPVLD (P41720) Serine/threonine-protein kinase 1 (EC 2.7.11.1)| Length = 274 Score = 44.7 bits (104), Expect = 2e-04 Identities = 28/88 (31%), Positives = 49/88 (55%), Gaps = 2/88 (2%) Frame = +2 Query: 227 NVLVMDLLGPSLEDLFNFCSRKLSLKT--VLMLADQMINRVEFVHSKSFLHRDIKPDNFL 400 ++LVMD + DLF+ + L+ + ++A Q+I+ ++ +H + +H D+K +N L Sbjct: 83 HLLVMDYIPDG--DLFDLMQTEPRLREPEISLIAYQLIDALQALHKHNVVHNDVKLENVL 140 Query: 401 MGLGRRANQVYVIDFGLAKKYRDTSTHQ 484 RR Q+YV D+GL K ST + Sbjct: 141 Y---RRFEQIYVCDYGLCKIAGSPSTFE 165
>CSK22_YEAST (P19454) Casein kinase II subunit alpha' (EC 2.7.11.1) (CK II)| Length = 338 Score = 44.7 bits (104), Expect = 2e-04 Identities = 41/141 (29%), Positives = 70/141 (49%), Gaps = 6/141 (4%) Frame = +2 Query: 59 EIYLGTNIQTNEEVGIK-LENVKTKHPQLLYESKIYR---ILQGGTGIPNV-RWFGVEGD 223 E++ G I N++ IK L+ VK K KIYR IL TG PNV + + D Sbjct: 62 EVFSGRCIVNNQKCVIKVLKPVKMK--------KIYRELKILTNLTGGPNVVGLYDIVQD 113 Query: 224 YNVLVMDLLGPSLEDL-FNFCSRKLSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFL 400 + + L+ ++++ F L + Q++ +++ HS +HRD+KP N + Sbjct: 114 ADSKIPALIFEEIKNVDFRTLYPTFKLPDIQYYFTQLLIALDYCHSMGIMHRDVKPQNVM 173 Query: 401 MGLGRRANQVYVIDFGLAKKY 463 + R ++ +ID+GLA+ Y Sbjct: 174 IDPTER--KLRLIDWGLAEFY 192
>HT1_ARATH (Q2MHE4) Serine/threonine-protein kinase HT1 (EC 2.7.11.1) (High| leaf temperature protein 1) Length = 390 Score = 44.7 bits (104), Expect = 2e-04 Identities = 34/104 (32%), Positives = 52/104 (50%) Frame = +2 Query: 293 LSLKTVLMLADQMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKYRDT 472 LS++TVL LA + +E++HS+ +HRD+K +N L+ R V V DFG Sbjct: 184 LSIETVLRLALDISRGMEYLHSQGVIHRDLKSNNLLLNDEMR---VKVADFG-------- 232 Query: 473 STHQHIPYRENKNLTGTARYASVNTHLGIEQSRRDDLESLGYVL 604 ++ RE K GT R+ + +R+ D+ S G VL Sbjct: 233 TSCLETQCREAKGNMGTYRWMAPEMIKEKPYTRKVDVYSFGIVL 276
>CDC2_SCHPO (P04551) Cell division control protein 2 (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinse) Length = 297 Score = 44.7 bits (104), Expect = 2e-04 Identities = 25/76 (32%), Positives = 42/76 (55%), Gaps = 5/76 (6%) Frame = +2 Query: 326 QMINRVEFVHSKSFLHRDIKPDNFLMGLGRRANQVYVIDFGLAKKY---RDTSTHQHIP- 493 Q++N V F HS+ +HRD+KP N L+ + + + DFGLA+ + TH+ + Sbjct: 117 QLVNGVNFCHSRRIIHRDLKPQNLLID---KEGNLKLADFGLARSFGVPLRNYTHEIVTL 173 Query: 494 -YRENKNLTGTARYAS 538 YR + L G+ Y++ Sbjct: 174 WYRAPEVLLGSRHYST 189 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 94,259,854 Number of Sequences: 219361 Number of extensions: 2051168 Number of successful extensions: 7628 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 7293 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 7514 length of database: 80,573,946 effective HSP length: 107 effective length of database: 57,102,319 effective search space used: 5538924943 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
