>AP1G1_USTMA (Q99128) AP-1 complex subunit gamma-1 (Gamma(1)-adaptin) (Clathrin|
           assembly protein large gamma-1 chain) (Clathrin assembly
           protein complex 1 gamma-1 large chain) (Gamma-ADA)
          Length = 853

 Score = 94.7 bits (234), Expect = 2e-19
 Identities = 42/85 (49%), Positives = 65/85 (76%)
 Frame = +1

Query: 295 IIVDTQAVQRHRVSILECVKDADAPIRKRALELVYLLVNDTNVKLLTKKLVDYLKVANPD 474
           + +DT AVQRHR  IL+C++D D  IR+RALEL Y L+N++NV++LT++L+ +L+VA+ +
Sbjct: 338 VSMDTNAVQRHRNIILDCLRDGDISIRRRALELSYALINESNVRVLTRELLSFLEVADNE 397

Query: 475 FKEDLRAKICSMAEKFSQEKLWYLD 549
           FK  +  +IC  AEKF+  K W++D
Sbjct: 398 FKLGMTTQICLAAEKFAPNKRWHID 422

>AP1G1_MOUSE (P22892) AP-1 complex subunit gamma-1 (Adapter-related protein|
           complex 1 gamma-1 subunit) (Gamma-adaptin) (Adaptor
           protein complex AP-1 gamma-1 subunit) (Golgi adaptor
           HA1/AP1 adaptin subunit gamma-1) (Clathrin assembly
           protein complex 1 gamm
          Length = 821

 Score = 77.4 bits (189), Expect = 3e-14
 Identities = 35/82 (42%), Positives = 55/82 (67%)
 Frame = +1

Query: 304 DTQAVQRHRVSILECVKDADAPIRKRALELVYLLVNDTNVKLLTKKLVDYLKVANPDFKE 483
           D  AVQRHR +I++C+KD D  I++RA+EL + LVN  N++ + K+L+ +L    P+FK 
Sbjct: 338 DHNAVQRHRSTIVDCLKDLDVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKA 397

Query: 484 DLRAKICSMAEKFSQEKLWYLD 549
           D  + I   AEK++  K W++D
Sbjct: 398 DCASGIFLAAEKYAPSKRWHID 419

>AP1G1_HUMAN (O43747) AP-1 complex subunit gamma-1 (Adapter-related protein|
           complex 1 gamma-1 subunit) (Gamma-adaptin) (Adaptor
           protein complex AP-1 gamma-1 subunit) (Golgi adaptor
           HA1/AP1 adaptin subunit gamma-1) (Clathrin assembly
           protein complex 1 gamm
          Length = 821

 Score = 77.4 bits (189), Expect = 3e-14
 Identities = 35/82 (42%), Positives = 55/82 (67%)
 Frame = +1

Query: 304 DTQAVQRHRVSILECVKDADAPIRKRALELVYLLVNDTNVKLLTKKLVDYLKVANPDFKE 483
           D  AVQRHR +I++C+KD D  I++RA+EL + LVN  N++ + K+L+ +L    P+FK 
Sbjct: 338 DHNAVQRHRSTIVDCLKDLDVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKA 397

Query: 484 DLRAKICSMAEKFSQEKLWYLD 549
           D  + I   AEK++  K W++D
Sbjct: 398 DCASGIFLAAEKYAPSKRWHID 419

>AP1G2_HUMAN (O75843) AP-1 complex subunit gamma-2 (Adapter-related protein|
           complex 1 gamma-2 subunit) (Gamma2-adaptin) (Adaptor
           protein complex AP-1 gamma-2 subunit) (G2ad)
          Length = 785

 Score = 72.8 bits (177), Expect = 6e-13
 Identities = 33/82 (40%), Positives = 54/82 (65%)
 Frame = +1

Query: 304 DTQAVQRHRVSILECVKDADAPIRKRALELVYLLVNDTNVKLLTKKLVDYLKVANPDFKE 483
           D  AVQRHR +++EC+++ DA + +RALEL   LVN +NV+ + ++L  +L+   PD + 
Sbjct: 340 DHSAVQRHRPTVVECLRETDASLSRRALELSLALVNSSNVRAMMQELQAFLESCPPDLRA 399

Query: 484 DLRAKICSMAEKFSQEKLWYLD 549
           D  + I   AE+F+  K W++D
Sbjct: 400 DCASGILLAAERFAPTKRWHID 421

>AP1G2_MOUSE (O88512) AP-1 complex subunit gamma-2 (Adapter-related protein|
           complex 1 gamma-2 subunit) (Gamma2-adaptin) (Adaptor
           protein complex AP-1 gamma-2 subunit) (G2ad)
          Length = 791

 Score = 72.8 bits (177), Expect = 6e-13
 Identities = 33/82 (40%), Positives = 54/82 (65%)
 Frame = +1

Query: 304 DTQAVQRHRVSILECVKDADAPIRKRALELVYLLVNDTNVKLLTKKLVDYLKVANPDFKE 483
           D  AVQRHR +++EC+++ DA + +RALEL   LVN +NV+ + ++L  +L+   PD + 
Sbjct: 340 DHSAVQRHRSTVVECLQETDASLSRRALELSLALVNSSNVRAMMQELQAFLESCPPDLRA 399

Query: 484 DLRAKICSMAEKFSQEKLWYLD 549
           D  + I   AE+F+  K W++D
Sbjct: 400 DCASGILLAAERFAPSKRWHID 421

>AP1G1_SCHPO (Q9UU81) AP-1 complex subunit gamma-1 (Gamma(1)-adaptin) (Clathrin|
           assembly protein large gamma-1 chain) (Clathrin assembly
           protein complex 1 gamma-1 large chain)
          Length = 865

 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 29/84 (34%), Positives = 48/84 (57%)
 Frame = +1

Query: 304 DTQAVQRHRVSILECVKDADAPIRKRALELVYLLVNDTNVKLLTKKLVDYLKVANPDFKE 483
           +  AVQRHR +IL C+ D D+ I+ RALEL   LVN+ NV+ + ++L+ +L   + + + 
Sbjct: 367 EENAVQRHRSTILACLNDVDSSIQSRALELSTFLVNEANVRFMVRELLSFLDNVSDELRG 426

Query: 484 DLRAKICSMAEKFSQEKLWYLDQM 555
                I  +   F+  K W+ D +
Sbjct: 427 STAQYITEVTNAFAPNKRWHFDTL 450

>SACS_HUMAN (Q9NZJ4) Sacsin|
          Length = 3829

 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 32/86 (37%), Positives = 49/86 (56%), Gaps = 2/86 (2%)
 Frame = +1

Query: 1   PEGTTALRELIQNTDDTGASRVLLCLDRRAHGSY--SLLGPALAQWQGPALLAHNDAAFT 174
           P  +   +EL+QN DD  A+     +D R +     +LL P +A   GPAL + N++ F+
Sbjct: 722 PSVSDIFKELLQNADDANATECSFLIDMRRNMDIRENLLDPGMAACHGPALWSFNNSQFS 781

Query: 175 DNDFASISRIGGSKKAS*AWKTGRFG 252
           D+DF +I+R+G S K     K G+FG
Sbjct: 782 DSDFVNITRLGESLKRGEVDKVGKFG 807



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 29/84 (34%), Positives = 42/84 (50%)
 Frame = +1

Query: 1    PEGTTALRELIQNTDDTGASRVLLCLDRRAHGSYSLLGPALAQWQGPALLAHNDAAFTDN 180
            P     L+EL+QN DD  A+ +    D R H    +     A  QGPAL  +N+  FT++
Sbjct: 1790 PSEKEMLKELLQNADDAKATEICFVFDPRQHPVDRIFDDKWAPLQGPALCVYNNQPFTED 1849

Query: 181  DFASISRIGGSKKAS*AWKTGRFG 252
            D   I  +G   K    +KTG++G
Sbjct: 1850 DVRGIQNLGKGTKEGNPYKTGQYG 1873

>SACS_MOUSE (Q9JLC8) Sacsin|
          Length = 3830

 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 32/86 (37%), Positives = 49/86 (56%), Gaps = 2/86 (2%)
 Frame = +1

Query: 1   PEGTTALRELIQNTDDTGASRVLLCLDRRAHGSY--SLLGPALAQWQGPALLAHNDAAFT 174
           P  +   +EL+QN DD  A+     +D R +     +LL P +A   GPAL + N++ F+
Sbjct: 722 PSVSDIFKELLQNADDANATECSFMIDMRRNMDIRENLLDPGMAACHGPALWSFNNSEFS 781

Query: 175 DNDFASISRIGGSKKAS*AWKTGRFG 252
           D+DF +I+R+G S K     K G+FG
Sbjct: 782 DSDFLNITRLGESLKRGEVDKVGKFG 807



 Score = 55.8 bits (133), Expect = 8e-08
 Identities = 29/84 (34%), Positives = 40/84 (47%)
 Frame = +1

Query: 1    PEGTTALRELIQNTDDTGASRVLLCLDRRAHGSYSLLGPALAQWQGPALLAHNDAAFTDN 180
            P     L+EL+QN DD  A+ +    D R H    +     A  QGPAL  +N+  FT++
Sbjct: 1790 PSEKEMLKELLQNADDAKATEICFVFDPRQHPVDRIFDDKWAPLQGPALCVYNNQPFTED 1849

Query: 181  DFASISRIGGSKKAS*AWKTGRFG 252
            D   I  +G   K     KTG +G
Sbjct: 1850 DVRGIQNLGKGTKEGNPCKTGHYG 1873

>AP4E1_HUMAN (Q9UPM8) AP-4 complex subunit epsilon-1 (Adapter-related protein|
           complex 4 epsilon-1 subunit) (Epsilon subunit of AP-4)
           (AP-4 adapter complex epsilon subunit)
          Length = 1137

 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 24/85 (28%), Positives = 51/85 (60%), Gaps = 1/85 (1%)
 Frame = +1

Query: 304 DTQAVQRHRVSILECVKDADAPIRKRALELVYLLVNDTNVKLLTKKLVDYLKVANPDFK- 480
           D     +H+++I+EC+   D  I++  LEL+Y + N  N+ ++ +K+++YL  +  ++  
Sbjct: 367 DPTLALQHQMTIIECLDHPDPIIKRETLELLYRITNAQNITVIVQKMLEYLHQSKEEYVI 426

Query: 481 EDLRAKICSMAEKFSQEKLWYLDQM 555
            +L  KI  +AEK++ +  W++  M
Sbjct: 427 VNLVGKIAELAEKYAPDNAWFIQTM 451

>AP2A2_RAT (P18484) AP-2 complex subunit alpha-2 (Adapter-related protein|
           complex 2 alpha-2 subunit) (Alpha-adaptin C) (Adaptor
           protein complex AP-2 alpha-2 subunit) (Clathrin assembly
           protein complex 2 alpha-C large chain) (100 kDa coated
           vesicle protein
          Length = 937

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 22/81 (27%), Positives = 53/81 (65%), Gaps = 1/81 (1%)
 Frame = +1

Query: 310 QAVQRHRVSILECVK-DADAPIRKRALELVYLLVNDTNVKLLTKKLVDYLKVANPDFKED 486
           +AV+ H  +++  +K + D  +R+RA++L+Y + + +N + +  +++ YL+ A+   +E+
Sbjct: 362 EAVKTHIETVINALKTERDVSVRQRAVDLLYAMCDRSNAQQIVAEMLSYLETADYSIREE 421

Query: 487 LRAKICSMAEKFSQEKLWYLD 549
           +  K+  +AEK++ +  WY+D
Sbjct: 422 IVLKVAILAEKYAVDYTWYVD 442

>AP2A2_MOUSE (P17427) AP-2 complex subunit alpha-2 (Adapter-related protein|
           complex 2 alpha-2 subunit) (Alpha-adaptin C) (Adaptor
           protein complex AP-2 alpha-2 subunit) (Clathrin assembly
           protein complex 2 alpha-C large chain) (100 kDa coated
           vesicle prote
          Length = 938

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 22/81 (27%), Positives = 53/81 (65%), Gaps = 1/81 (1%)
 Frame = +1

Query: 310 QAVQRHRVSILECVK-DADAPIRKRALELVYLLVNDTNVKLLTKKLVDYLKVANPDFKED 486
           +AV+ H  +++  +K + D  +R+RA++L+Y + + +N + +  +++ YL+ A+   +E+
Sbjct: 363 EAVKTHIETVINALKTERDVSVRQRAVDLLYAMCDRSNAQQIVAEMLSYLETADYSIREE 422

Query: 487 LRAKICSMAEKFSQEKLWYLD 549
           +  K+  +AEK++ +  WY+D
Sbjct: 423 IVLKVAILAEKYAVDYTWYVD 443

>AP2A_SCHPO (Q9C0W7) AP-2 complex subunit alpha (Alpha-adaptin) (Clathrin|
           assembly protein large alpha chain) (Clathrin assembly
           protein complex 2 alpha large chain)
          Length = 878

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 24/79 (30%), Positives = 50/79 (63%)
 Frame = +1

Query: 313 AVQRHRVSILECVKDADAPIRKRALELVYLLVNDTNVKLLTKKLVDYLKVANPDFKEDLR 492
           +++ ++  IL  ++  D  +RK++LEL+Y++ ++ N KL+   L+ YL   +   +EDL 
Sbjct: 355 SLKHYKELILSSLRYKDVSLRKKSLELLYMMCDEENAKLIVADLLQYLPHLDSVTQEDLI 414

Query: 493 AKICSMAEKFSQEKLWYLD 549
           +K+  ++E F+ +  WY+D
Sbjct: 415 SKVAIISETFATDYEWYVD 433

>AP2A2_HUMAN (O94973) AP-2 complex subunit alpha-2 (Adapter-related protein|
           complex 2 alpha-2 subunit) (Alpha-adaptin C) (Adaptor
           protein complex AP-2 alpha-2 subunit) (Clathrin assembly
           protein complex 2 alpha-C large chain) (100 kDa coated
           vesicle prote
          Length = 939

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 22/81 (27%), Positives = 52/81 (64%), Gaps = 1/81 (1%)
 Frame = +1

Query: 310 QAVQRHRVSILECVK-DADAPIRKRALELVYLLVNDTNVKLLTKKLVDYLKVANPDFKED 486
           +AV+ H  +++  +K + D  +R+RA++L+Y + + +N   +  +++ YL+ A+   +E+
Sbjct: 363 EAVKTHIETVINALKTERDVSVRQRAVDLLYAMCDRSNAPQIVAEMLSYLETADYSIREE 422

Query: 487 LRAKICSMAEKFSQEKLWYLD 549
           +  K+  +AEK++ +  WY+D
Sbjct: 423 IVLKVAILAEKYAVDYTWYVD 443

>AP2A1_MOUSE (P17426) AP-2 complex subunit alpha-1 (Adapter-related protein|
           complex 2 alpha-1 subunit) (Alpha-adaptin A) (Adaptor
           protein complex AP-2 alpha-1 subunit) (Clathrin assembly
           protein complex 2 alpha-A large chain) (100 kDa coated
           vesicle prote
          Length = 977

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 23/81 (28%), Positives = 52/81 (64%), Gaps = 1/81 (1%)
 Frame = +1

Query: 310 QAVQRHRVSILECVK-DADAPIRKRALELVYLLVNDTNVKLLTKKLVDYLKVANPDFKED 486
           +AV+ H  +++  +K + D  +R+RA +L+Y + + +N K +  +++ YL+ A+   +E+
Sbjct: 364 EAVKTHIDTVINALKTERDVSVRQRAADLLYAMCDRSNAKQIVSEMLRYLETADYAIREE 423

Query: 487 LRAKICSMAEKFSQEKLWYLD 549
           +  K+  +AEK++ +  WY+D
Sbjct: 424 IVLKVAILAEKYAVDYSWYVD 444

>AP2A1_HUMAN (O95782) AP-2 complex subunit alpha-1 (Adapter-related protein|
           complex 2 alpha-1 subunit) (Alpha-adaptin A) (Adaptor
           protein complex AP-2 alpha-1 subunit) (Clathrin assembly
           protein complex 2 alpha-A large chain) (100 kDa coated
           vesicle prote
          Length = 977

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 23/81 (28%), Positives = 52/81 (64%), Gaps = 1/81 (1%)
 Frame = +1

Query: 310 QAVQRHRVSILECVK-DADAPIRKRALELVYLLVNDTNVKLLTKKLVDYLKVANPDFKED 486
           +AV+ H  +++  +K + D  +R+RA +L+Y + + +N K +  +++ YL+ A+   +E+
Sbjct: 364 EAVKTHIDTVINALKTERDVSVRQRAADLLYAMCDRSNAKQIVSEMLRYLETADYAIREE 423

Query: 487 LRAKICSMAEKFSQEKLWYLD 549
           +  K+  +AEK++ +  WY+D
Sbjct: 424 IVLKVAILAEKYAVDYSWYVD 444

>AP4E1_MOUSE (Q80V94) AP-4 complex subunit epsilon-1 (Adapter-related protein|
           complex 4 epsilon-1 subunit) (Epsilon subunit of AP-4)
           (AP-4 adapter complex epsilon subunit)
          Length = 1122

 Score = 52.4 bits (124), Expect = 9e-07
 Identities = 23/85 (27%), Positives = 49/85 (57%), Gaps = 1/85 (1%)
 Frame = +1

Query: 304 DTQAVQRHRVSILECVKDADAPIRKRALELVYLLVNDTNVKLLTKKLVDYLKVANPD-FK 480
           D     +H+++I+ C+   D  I++  LEL+Y + N  NV ++ +K+++YL  +  +   
Sbjct: 366 DPSLALQHQITIIGCLDHPDPIIKRETLELLYRITNAQNVVVIVQKMLEYLHQSKEEHII 425

Query: 481 EDLRAKICSMAEKFSQEKLWYLDQM 555
             L  +I  +AEK++ + +W++  M
Sbjct: 426 ISLVGRIAELAEKYAPDNVWFIQTM 450

>AP2A_DROME (P91926) AP-2 complex subunit alpha (Alpha-adaptin)|
          Length = 940

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 22/81 (27%), Positives = 52/81 (64%), Gaps = 1/81 (1%)
 Frame = +1

Query: 310 QAVQRHR-VSILECVKDADAPIRKRALELVYLLVNDTNVKLLTKKLVDYLKVANPDFKED 486
           + V++H+ V IL    + D  +R+ A++L+Y + +  N + + +++++YL+ A+   +E+
Sbjct: 364 EEVKKHQEVVILSMKMEKDVSVRQMAVDLLYAMCDRGNAEEIVQEMLNYLETADYSIREE 423

Query: 487 LRAKICSMAEKFSQEKLWYLD 549
           +  K+  +AEK++ +  WY+D
Sbjct: 424 MVLKVAILAEKYATDYTWYVD 444

>AP1G1_YEAST (Q12028) AP-1 complex subunit gamma-1 (Gamma(1)-adaptin) (Clathrin|
           assembly protein large gamma-1 chain) (Clathrin assembly
           protein complex 1 gamma-1 large chain)
          Length = 832

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 29/83 (34%), Positives = 48/83 (57%), Gaps = 4/83 (4%)
 Frame = +1

Query: 313 AVQRHRVSILECVKDADAPIRKRALELVYLLVNDTNVKLLTKKLVDYLKVANPDFKEDLR 492
           AVQRHR  I  C++D D  IR RALEL + +++D+N+  L  +L+ +L   + D K+ + 
Sbjct: 372 AVQRHRKFISHCLQDTDVSIRMRALELSFAILDDSNLVELVNELMKFLAKQDEDSKDLII 431

Query: 493 AKICSMAEKFS----QEKLWYLD 549
             I  + + F     +++ W LD
Sbjct: 432 YTIDHLIDTFDTRVVKDESWKLD 454

>AP3D1_MOUSE (O54774) AP-3 complex subunit delta-1 (Adapter-related protein|
           complex 3 delta-1 subunit) (Delta-adaptin 3) (AP-3
           complex delta subunit) (Delta-adaptin) (mBLVR1)
          Length = 1199

 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 26/84 (30%), Positives = 50/84 (59%), Gaps = 5/84 (5%)
 Frame = +1

Query: 310 QAVQRHRVSILECVKDADAPIRKRALELVYLLVNDTNVKLLTKKLVDYL-KVANPDFKED 486
           ++VQ H+  IL+C+ D D  IR RAL+L+Y +V+  N+  + KKL+ ++ K     ++++
Sbjct: 336 KSVQSHKDLILQCLDDKDESIRLRALDLLYGMVSKKNLMEIVKKLMTHVDKAEGTTYRDE 395

Query: 487 LRAKICSMAEKFSQEKL----WYL 546
           L  KI  +  + + + +    WY+
Sbjct: 396 LLTKIIDICSQSNYQHITNFEWYI 419

>AP3D1_BOVIN (Q865S1) AP-3 complex subunit delta-1 (Adapter-related protein|
           complex 3 delta-1 subunit) (Delta-adaptin 3) (AP-3
           complex delta subunit) (Delta-adaptin)
          Length = 1207

 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 25/84 (29%), Positives = 50/84 (59%), Gaps = 5/84 (5%)
 Frame = +1

Query: 310 QAVQRHRVSILECVKDADAPIRKRALELVYLLVNDTNVKLLTKKLVDYL-KVANPDFKED 486
           ++VQ H+  +L+C+ D D  IR RAL+L+Y +V+  N+  + KKL+ ++ K     ++++
Sbjct: 336 KSVQAHKDLVLQCLDDKDESIRLRALDLLYGMVSKKNLMEIVKKLMTHVDKAEGTTYRDE 395

Query: 487 LRAKICSMAEKFSQEKL----WYL 546
           L  KI  +  + + + +    WY+
Sbjct: 396 LLTKIIDICSQSNYQHITNFEWYI 419

>AP3D1_HUMAN (O14617) AP-3 complex subunit delta-1 (Adapter-related protein|
           complex 3 delta-1 subunit) (Delta-adaptin 3) (AP-3
           complex delta subunit) (Delta-adaptin)
          Length = 1153

 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 26/84 (30%), Positives = 50/84 (59%), Gaps = 5/84 (5%)
 Frame = +1

Query: 310 QAVQRHRVSILECVKDADAPIRKRALELVYLLVNDTNVKLLTKKLVDYL-KVANPDFKED 486
           ++VQ H+  IL+C+ D D  IR RAL+L+Y +V+  N+  + KKL+ ++ K     ++++
Sbjct: 336 KSVQSHKDLILQCLDDKDESIRLRALDLLYGMVSKKNLMEIVKKLMTHVDKAEGTTYRDE 395

Query: 487 LRAKICSMAEKFSQEKL----WYL 546
           L  KI  +  + + + +    WY+
Sbjct: 396 LLTKIIDICSQSNYQYITNFEWYI 419

>AP3D_DROME (P54362) AP-3 complex subunit delta (Delta-adaptin) (Garnet|
           protein) (Delta adaptin subunit of AP-3)
          Length = 1034

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 26/84 (30%), Positives = 49/84 (58%), Gaps = 5/84 (5%)
 Frame = +1

Query: 310 QAVQRHRVSILECVKDADAPIRKRALELVYLLVNDTNVKLLTKKLVDYLKVANPD-FKED 486
           ++VQ H+  IL C+ D D  IR RAL+L+Y +V+  N+  + K+L+ +++ A    ++++
Sbjct: 337 KSVQAHKDLILACLDDKDESIRLRALDLLYGMVSKKNLMEIVKRLLGHMERAEGSAYRDE 396

Query: 487 LRAKICSMAEKFSQEKL----WYL 546
           L  K+  +  + S   +    WYL
Sbjct: 397 LLYKVIEICAQSSYLYVTNFEWYL 420

>AP2A_YEAST (P38065) AP-2 complex subunit alpha (Alpha-adaptin) (Clathrin|
           assembly protein large alpha chain) (Clathrin assembly
           protein complex 2 alpha large chain)
          Length = 1025

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 18/68 (26%), Positives = 38/68 (55%), Gaps = 4/68 (5%)
 Frame = +1

Query: 355 DADAPIRKRALELVYLLVNDTNVKLLTKKLVDYL----KVANPDFKEDLRAKICSMAEKF 522
           + D+ I ++ ++L+Y   +  NVK++   L+ Y+     +A P  K D+  KI  + EK+
Sbjct: 436 ERDSSIVRKVVDLLYTFTDVENVKIIVDGLLQYILSPKNLAEPQIKSDIAVKIAILTEKY 495

Query: 523 SQEKLWYL 546
           + +  W++
Sbjct: 496 ATDINWFV 503

>AP3D_SCHPO (Q9UTL8) AP-3 complex subunit delta (Adapter-related protein|
           complex 3 delta subunit) (Delta-adaptin 3) (AP-3 complex
           delta subunit) (Delta-adaptin)
          Length = 834

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 22/53 (41%), Positives = 34/53 (64%), Gaps = 1/53 (1%)
 Frame = +1

Query: 337 ILECVKDADAPIRKRALELVYLLVNDTNVKLLTKKLVDYLKVANPDFK-EDLR 492
           IL+C+ D D  IR RAL+LV  +VN  N++ + K L+  L V++ +   ED+R
Sbjct: 332 ILKCLVDTDTSIRLRALDLVNEIVNKENIRTIVKTLMLQLIVSSDESAVEDIR 384

>AP3D_YEAST (Q08951) AP-3 complex subunit delta (Adapter-related protein|
           complex 3 delta subunit) (Delta-adaptin 3) (AP-3 complex
           delta subunit) (Delta-adaptin)
          Length = 932

 Score = 33.5 bits (75), Expect = 0.42
 Identities = 15/49 (30%), Positives = 29/49 (59%)
 Frame = +1

Query: 301 VDTQAVQRHRVSILECVKDADAPIRKRALELVYLLVNDTNVKLLTKKLV 447
           ++T  + R    I+  + D D  IR +A+ELV  +V++ N+K + + L+
Sbjct: 344 INTDFISRFDQLIIRLLSDVDVSIRSKAIELVEGIVDEDNLKAIVQTLM 392

>AMPN_LACHE (Q10730) Aminopeptidase N (EC 3.4.11.2) (Lysyl aminopeptidase)|
           (Lys-AP) (Alanine aminopeptidase)
          Length = 844

 Score = 31.6 bits (70), Expect = 1.6
 Identities = 14/41 (34%), Positives = 26/41 (63%), Gaps = 4/41 (9%)
 Frame = +1

Query: 397 YLLVNDT----NVKLLTKKLVDYLKVANPDFKEDLRAKICS 507
           Y+L+N+     N +L+ K + +Y + A+P +K DLR+ + S
Sbjct: 674 YVLINEVKNFGNAELVDKLIKEYQRTADPSYKVDLRSAVTS 714

>RIF1_SCHPO (Q96UP3) Telomere length regulator protein rif1|
          Length = 1400

 Score = 31.2 bits (69), Expect = 2.1
 Identities = 24/66 (36%), Positives = 36/66 (54%), Gaps = 2/66 (3%)
 Frame = +1

Query: 337 ILECVKDADAPIRKRALELVYLLVNDTNVKLLTKKLVDYLKVANPDFKEDLR--AKICSM 510
           +L C+ DA  PIR++AL    LL  D +  L   KLV    +AN  F+ D++  A +  M
Sbjct: 281 LLACLVDASRPIREKAL----LLALDLSKHLYHDKLVARTILAN--FRSDIKGTAFVLIM 334

Query: 511 AEKFSQ 528
            E+F +
Sbjct: 335 TEQFEK 340

>AP3D_ASHGO (Q755A1) AP-3 complex subunit delta (Adapter-related protein|
           complex 3 delta subunit) (Delta-adaptin 3) (AP-3 complex
           delta subunit) (Delta-adaptin)
          Length = 899

 Score = 30.8 bits (68), Expect = 2.7
 Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 4/62 (6%)
 Frame = +1

Query: 301 VDTQAVQRHRVSILECVKDADAPIRKRALELVYLLVNDTN----VKLLTKKLVDYLKVAN 468
           ++T  +    V IL  + D D  IR + LEL+  +V + N    V+ L K+ VD  K+  
Sbjct: 342 INTDFIANFDVLILRLLVDVDVSIRSKTLELLEGIVTEDNLVDFVQRLLKQFVDVDKICV 401

Query: 469 PD 474
            D
Sbjct: 402 ND 403

>ACT1_ECHGR (P35432) Actin-1|
          Length = 375

 Score = 30.0 bits (66), Expect = 4.6
 Identities = 23/80 (28%), Positives = 37/80 (46%)
 Frame = +1

Query: 292 GIIVDTQAVQRHRVSILECVKDADAPIRKRALELVYLLVNDTNVKLLTKKLVDYLKVANP 471
           GI++D+     H V I E      A +R   L+L    + D   KLLT++   +   A  
Sbjct: 150 GIVLDSGDGVSHTVPIYEGYALPHAILR---LDLAGRDLTDWLTKLLTERGYAFTTTAEL 206

Query: 472 DFKEDLRAKICSMAEKFSQE 531
           +   D++ K+C +A  F  E
Sbjct: 207 EIVRDIKEKLCYVALDFENE 226

>NPBL_CAEEL (Q95XZ5) Nipped-B-like protein pqn-85|
            (Prion-like-(Q/n-rich)-domain-bearing protein 85) (SCC2
            homolog)
          Length = 2203

 Score = 29.3 bits (64), Expect = 7.9
 Identities = 13/45 (28%), Positives = 27/45 (60%)
 Frame = +1

Query: 277  EHTYDGIIVDTQAVQRHRVSILECVKDADAPIRKRALELVYLLVN 411
            E    G  + +  +Q++  ++LE   DAD  +R+ A+++V+L +N
Sbjct: 1816 EMELSGSGLGSSVIQKYWKAVLESYVDADIQLRRAAVQVVWLTLN 1860


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 63,981,573
Number of Sequences: 219361
Number of extensions: 1107808
Number of successful extensions: 3706
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 3633
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3701
length of database: 80,573,946
effective HSP length: 105
effective length of database: 57,541,041
effective search space used: 4545742239
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)