ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | baal13a24 |
|---|---|
| Clone Library Name | barley_pub |
>MYO4_CAEEL (P02566) Myosin-4 (Myosin heavy chain B) (MHC B) (Uncoordinated| protein 54) Length = 1966 Score = 48.1 bits (113), Expect = 2e-05 Identities = 46/195 (23%), Positives = 87/195 (44%), Gaps = 1/195 (0%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELD 197 E K QL + E+ + +LE + D ++L L D L + + A +R Sbjct: 904 ESTKTQLSDAEERLAKLEAQQKDASKQLSELN----------DQLADNEDRTADVQRAKK 953 Query: 198 NSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQE 377 EAE KQI DL+ LR+ ES+ + + Q R QD + +DE + + +E Sbjct: 954 KIEAEVEALKKQIQDLEMSLRKAESEKQSKDHQIRSLQDEMQQQDEAIAKLNKEKKHQEE 1013 Query: 378 MDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDRT-GEQ 554 ++ + LQ+E ++ + + A +Q +++ L +R + +L + + + GE Sbjct: 1014 INRKLMEDLQSE-EDKGNHQNKVKAKLEQTLDDLEDS-LEREKRARADLDKQKRKVEGEL 1071 Query: 555 DVSQAAQDGSAESSY 599 ++Q D S + Sbjct: 1072 KIAQENIDESGRQRH 1086 Score = 35.0 bits (79), Expect = 0.19 Identities = 49/192 (25%), Positives = 80/192 (41%), Gaps = 7/192 (3%) Frame = +3 Query: 21 KLKEQLHERE-------KYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIAS 179 KL E L E K +LE L+D D+L+ + +A R+ E+ Sbjct: 1017 KLMEDLQSEEDKGNHQNKVKAKLEQTLDDLE---DSLEREKRARADLDKQKRKVEGELKI 1073 Query: 180 FRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAW 359 + +D S +R HDL+ +L++KES E H V+ +L D A Sbjct: 1074 AQENIDESGRQR-------HDLENNLKKKES------ELHSVS--------SRLEDEQAL 1112 Query: 360 ITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRD 539 ++++Q I QS +EL E + Q + + ++Q+ EL EL + Sbjct: 1113 VSKLQR-QIKDGQSRISELEEELENERQSRSKADRAKSDLQR-----------ELEELGE 1160 Query: 540 RTGEQDVSQAAQ 575 + EQ + AAQ Sbjct: 1161 KLDEQGGATAAQ 1172 Score = 31.2 bits (69), Expect = 2.8 Identities = 20/85 (23%), Positives = 37/85 (43%) Frame = +3 Query: 9 VAAEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRR 188 +A E + E +R L+ K ++ H L+ + V Q +++ + I+ Sbjct: 1073 IAQENIDESGRQRHDLENNLKKKESELHSVSSRLEDEQALVSKLQRQIKDGQSRISELEE 1132 Query: 189 ELDNSEAERAQHLKQIHDLQEHLRE 263 EL+N R++ + DLQ L E Sbjct: 1133 ELENERQSRSKADRAKSDLQRELEE 1157
>GOGA1_MOUSE (Q9CW79) Golgin subfamily A member 1 (Golgin-97)| Length = 758 Score = 48.1 bits (113), Expect = 2e-05 Identities = 52/219 (23%), Positives = 95/219 (43%), Gaps = 23/219 (10%) Frame = +3 Query: 3 HVVAAEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASF 182 H + +K+ + E+EK I L+ K+ + L+ V Q+LL+E+T + Sbjct: 275 HSIDLQKVTAETQEKEKVITHLQEKVIFLEKRLEQNLSGEDHV---QELLKEKTVAEQNL 331 Query: 183 RRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWI 362 A R H K ++ L+ +++ E A EEQ +++ + ++ Q++ I Sbjct: 332 EDTRQQLLAARNSHTKALYLLETRVKDLERSLQAAEEQLSQSRNVVADQEAQIQKL---I 388 Query: 363 TRVQEMDILQSQ--SLQAELRER----------------TDQFG--QCWATFQQQYVEMQ 482 T QE + Q Q +L+ RER DQ Q QQ+ V ++ Sbjct: 389 TTNQENSLSQQQVLALEQHCRERIHALEAQIEALEQTRVADQIASEQGMLQLQQENVALK 448 Query: 483 QG---FLHTIQRLQLELIELRDRTGEQDVSQAAQDGSAE 590 + H++Q QLEL +L+D ++++ A + E Sbjct: 449 ESRNECEHSLQHHQLELKKLKDEWSQREIVSVAMAQALE 487
>MYH11_MOUSE (O08638) Myosin-11 (Myosin heavy chain, smooth muscle isoform)| (SMMHC) Length = 1972 Score = 45.4 bits (106), Expect = 1e-04 Identities = 52/217 (23%), Positives = 102/217 (47%), Gaps = 32/217 (14%) Frame = +3 Query: 15 AEKLKEQLHEREKYILELEMKLNDTHRELDTL--KIDHQAVWANQDL--LREQTNEIASF 182 A EQ+ + + I EL+M+L EL ++D + N L +RE I+ Sbjct: 1064 ASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDEEIAQKNNALKKIRELEGHISDL 1123 Query: 183 RRELDNSEAERAQHLKQIHDLQEHLREKESQY------LALEEQHRVAQD---NILYK-- 329 + +LD+ A R + KQ DL E L +++ A +++ R ++ +L K Sbjct: 1124 QEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKAL 1183 Query: 330 DEQLRDAHAWITRVQEMDILQSQSLQAELRERTDQFGQCWA-------TFQQQYVEM--- 479 DE+ R A +VQEM +Q+++ EL E+ +QF + A T +++ ++ Sbjct: 1184 DEETRSHEA---QVQEMRQKHTQAVE-ELTEQLEQFKRAKANLDKSKQTLEKENADLAGE 1239 Query: 480 -------QQGFLHTIQRLQLELIELRDRTGEQDVSQA 569 +Q H ++L+++L +L+ + + + ++A Sbjct: 1240 LRVLGQAKQEVEHKKKKLEVQLQDLQSKCSDGERARA 1276 Score = 39.3 bits (90), Expect = 0.010 Identities = 30/139 (21%), Positives = 69/139 (49%), Gaps = 4/139 (2%) Frame = +3 Query: 27 KEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTN---EIASFRRELD 197 +E++ +E+ + ++ + EL L+ H + + LL+EQ E+ + E+ Sbjct: 851 EEEMQAKEEEMQKITERQQKAETELKELEQKHTQLAEEKTLLQEQLQAETELYAESEEMR 910 Query: 198 NSEAERAQHLKQI-HDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQ 374 A + Q L++I H+++ L E+E + L+ + + +L +EQL + A ++Q Sbjct: 911 VRLAAKKQELEEILHEMEARLEEEEDRRQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 970 Query: 375 EMDILQSQSLQAELRERTD 431 L+ + +A++++ D Sbjct: 971 ----LEKVTAEAKIKKLED 985 Score = 38.1 bits (87), Expect = 0.023 Identities = 33/149 (22%), Positives = 65/149 (43%), Gaps = 7/149 (4%) Frame = +3 Query: 18 EKLKEQLHEREKYILE---LEMKLNDTHRELDTLKIDHQAVWANQDLLREQ----TNEIA 176 E+L+E+ R+K LE E K+ ++ + + + + LL E+ T +A Sbjct: 957 EQLEEEEAARQKLQLEKVTAEAKIKKLEDDILVMDDQNSKLSKERKLLEERVSDLTTNLA 1016 Query: 177 SFRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHA 356 + N +++H I +L+ L+++E LE+ R + + EQ+ D A Sbjct: 1017 EEEEKAKNLTKLKSKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQA 1076 Query: 357 WITRVQEMDILQSQSLQAELRERTDQFGQ 443 I ++ + + LQA L ++ Q Sbjct: 1077 QIAELKMQLAKKEEELQAALARLDEEIAQ 1105 Score = 32.3 bits (72), Expect = 1.3 Identities = 36/120 (30%), Positives = 62/120 (51%), Gaps = 10/120 (8%) Frame = +3 Query: 9 VAAEK--LKEQLH-EREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIAS 179 +A EK L+EQL E E Y EM++ ++ + +I H+ + + E Sbjct: 885 LAEEKTLLQEQLQAETELYAESEEMRVRLAAKKQELEEILHE--------MEARLEEEED 936 Query: 180 FRRELDNSEAERAQHLKQIHDLQEHLREKES--QYLALEE-----QHRVAQDNILYKDEQ 338 R++L +AER + +Q+ DL+E L E+E+ Q L LE+ + + +D+IL D+Q Sbjct: 937 RRQQL---QAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDDILVMDDQ 993
>MYH10_MOUSE (Q61879) Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle| myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B) Length = 1976 Score = 45.1 bits (105), Expect = 2e-04 Identities = 31/140 (22%), Positives = 74/140 (52%), Gaps = 4/140 (2%) Frame = +3 Query: 27 KEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTN---EIASFRRELD 197 +E+L +++ +L+++ K EL+ ++ HQ + +++L EQ E+ + E+ Sbjct: 851 EEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMR 910 Query: 198 NSEAERAQHLKQI-HDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQ 374 A + Q L++I HDL+ + E+E + L+ + + Q +I +EQL + ++Q Sbjct: 911 ARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQ 970 Query: 375 EMDILQSQSLQAELRERTDQ 434 L+ + +A++++ ++ Sbjct: 971 ----LEKVTAEAKIKKMEEE 986
>MYH10_HUMAN (P35580) Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle| myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B) Length = 1976 Score = 45.1 bits (105), Expect = 2e-04 Identities = 31/140 (22%), Positives = 74/140 (52%), Gaps = 4/140 (2%) Frame = +3 Query: 27 KEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTN---EIASFRRELD 197 +E+L +++ +L+++ K EL+ ++ HQ + +++L EQ E+ + E+ Sbjct: 851 EEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMR 910 Query: 198 NSEAERAQHLKQI-HDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQ 374 A + Q L++I HDL+ + E+E + L+ + + Q +I +EQL + ++Q Sbjct: 911 ARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQ 970 Query: 375 EMDILQSQSLQAELRERTDQ 434 L+ + +A++++ ++ Sbjct: 971 ----LEKVTAEAKIKKMEEE 986
>MYH10_BOVIN (Q27991) Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle| myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B) Length = 1976 Score = 45.1 bits (105), Expect = 2e-04 Identities = 31/140 (22%), Positives = 74/140 (52%), Gaps = 4/140 (2%) Frame = +3 Query: 27 KEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTN---EIASFRRELD 197 +E+L +++ +L+++ K EL+ ++ HQ + +++L EQ E+ + E+ Sbjct: 851 EEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMR 910 Query: 198 NSEAERAQHLKQI-HDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQ 374 A + Q L++I HDL+ + E+E + L+ + + Q +I +EQL + ++Q Sbjct: 911 ARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQ 970 Query: 375 EMDILQSQSLQAELRERTDQ 434 L+ + +A++++ ++ Sbjct: 971 ----LEKVTAEAKIKKMEEE 986
>LVA_DROME (Q8MSS1) Protein lava lamp| Length = 2779 Score = 45.1 bits (105), Expect = 2e-04 Identities = 49/198 (24%), Positives = 90/198 (45%), Gaps = 17/198 (8%) Frame = +3 Query: 33 QLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQD--LLREQTNEIASFRRELDNSE 206 QL E+E I+ L+ ++ + RE T K+ + + NQ+ LLR Q ++ + + S Sbjct: 2298 QLQEKESEIVHLKQRIEELMREDQTEKLVFEILTKNQELQLLRMQVKQLEEDKEDQQVSA 2357 Query: 207 AERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDE----------QLRDAHA 356 A + + L+ ++ + + +EE+ RV +++L E QL + Sbjct: 2358 APPKDDGETVEKLKSLCQQLQQEKSDMEEELRVLNNHVLSSLELEDRMKQTLLQLDTKNI 2417 Query: 357 WITRV-QEMDILQSQSL----QAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLE 521 IT + + ++ILQSQ+L AE Q W +Q VE + G + +I + L Sbjct: 2418 EITELRRSLEILQSQNLGQNSAAEQIPDLSAINQQW----EQLVEQKCGEVASIWQEHLS 2473 Query: 522 LIELRDRTGEQDVSQAAQ 575 E + ++V+Q Q Sbjct: 2474 QREAAFKAQLEEVTQQQQ 2491 Score = 38.5 bits (88), Expect = 0.017 Identities = 43/181 (23%), Positives = 81/181 (44%), Gaps = 7/181 (3%) Frame = +3 Query: 30 EQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIAS----FRRELD 197 E LH R I +LE++L++ ++ L+ + + + A+ +LD Sbjct: 1949 EHLHTR---IAQLELQLSNAEQQKTELQTKAAKLMKRLKEYKTKATTTATPTVTVDNDLD 2005 Query: 198 NSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQE 377 ++ E +H Q+ + + E+ SQ ALE++ + ++L D A + Q+ Sbjct: 2006 STIIEELKHQLQLQESRLSKAEEISQQHALEKEKLAKRIDVLTAG---NDRMAEMKERQD 2062 Query: 378 MDILQSQSLQAELRER---TDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDRTG 548 MD+ Q+ EL+E+ DQ+G+ AT + I+ LQ E+ +LR + Sbjct: 2063 MDVQMYQARIRELQEKLSQLDQWGEPAATVSS---SLDGDEAARIESLQQEIQQLRQQVS 2119 Query: 549 E 551 E Sbjct: 2120 E 2120
>MYH11_RABIT (P35748) Myosin-11 (Myosin heavy chain, smooth muscle isoform)| (SMMHC) Length = 1972 Score = 44.7 bits (104), Expect = 2e-04 Identities = 53/217 (24%), Positives = 102/217 (47%), Gaps = 32/217 (14%) Frame = +3 Query: 15 AEKLKEQLHEREKYILELEMKLNDTHRELDTL--KIDHQAVWANQDL--LREQTNEIASF 182 A L EQ+ + + I EL+M+L EL +++ + N L +RE I+ Sbjct: 1064 ASDLHEQIADLQAQIAELKMQLAKKEEELQAALARLEDETSQKNNALKKIRELEGHISDL 1123 Query: 183 RRELDNSEAERAQHLKQIHDLQEHLREKESQY------LALEEQHRVAQD---NILYK-- 329 + +LD+ A R + KQ DL E L +++ A +++ R ++ +L K Sbjct: 1124 QEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDTTATQQELRAKREQEVTVLKKAL 1183 Query: 330 DEQLRDAHAWITRVQEMDILQSQSLQAELRERTDQFGQCWA-------TFQQQYVEM--- 479 DE+ R A +VQEM +Q ++ EL E+ +QF + A T +++ ++ Sbjct: 1184 DEETRSHEA---QVQEMRQKHTQVVE-ELTEQLEQFKRAKANLDKTKQTLEKENADLAGE 1239 Query: 480 -------QQGFLHTIQRLQLELIELRDRTGEQDVSQA 569 +Q H ++L+++L EL+ + + + ++A Sbjct: 1240 LRVLGQAKQEVEHKKKKLEVQLQELQSKCSDGERARA 1276 Score = 40.4 bits (93), Expect = 0.005 Identities = 30/139 (21%), Positives = 70/139 (50%), Gaps = 4/139 (2%) Frame = +3 Query: 27 KEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTN---EIASFRRELD 197 +E++ +E + +++ + EL L+ H + ++LL+EQ E+ + E+ Sbjct: 851 EEEMQAKEDELQKIKERQQKAESELQELQQKHTQLSEEKNLLQEQLQAETELYAEAEEMR 910 Query: 198 NSEAERAQHLKQI-HDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQ 374 A + Q L++I H+++ L E+E + L+ + + +L +EQL + A ++Q Sbjct: 911 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 970 Query: 375 EMDILQSQSLQAELRERTD 431 L+ + +A++++ D Sbjct: 971 ----LEKVTAEAKIKKLED 985 Score = 37.0 bits (84), Expect = 0.051 Identities = 34/149 (22%), Positives = 62/149 (41%), Gaps = 7/149 (4%) Frame = +3 Query: 18 EKLKEQLHEREKYILE---LEMKLNDTHRELDTLKIDHQAVWANQDLLREQ----TNEIA 176 E+L+E+ R+K LE E K+ ++ + + + + LL E+ T +A Sbjct: 957 EQLEEEEAARQKLQLEKVTAEAKIKKLEDDILVMDDQNNKLSKERKLLEERISDLTTNLA 1016 Query: 177 SFRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHA 356 + N + +H I +L+ L+++E LE+ R EQ+ D A Sbjct: 1017 EEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKMDGEASDLHEQIADLQA 1076 Query: 357 WITRVQEMDILQSQSLQAELRERTDQFGQ 443 I ++ + + LQA L D+ Q Sbjct: 1077 QIAELKMQLAKKEEELQAALARLEDETSQ 1105
>GOGB1_HUMAN (Q14789) Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa| Golgi complex-associated protein) (GCP372) Length = 3259 Score = 44.7 bits (104), Expect = 2e-04 Identities = 44/205 (21%), Positives = 91/205 (44%), Gaps = 16/205 (7%) Frame = +3 Query: 42 EREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTN-----------EIASFRR 188 E + +LEM L + R+ ++D+++ A+ +LL EQ + +I + Sbjct: 761 ELRAQVKQLEMNLAEAERQR---RLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQN 817 Query: 189 ELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITR 368 ELD+ + + ++ I LQ L+ KES+ L E+ R + + L IT+ Sbjct: 818 ELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITK 877 Query: 369 VQEMDILQS---QSLQAELRERTDQFGQCWATFQQQYVEM-QQGFLHTIQRLQL-ELIEL 533 + ++ + + ++LQ + E+ Q + + ++ V++ ++ F ++ L E + L Sbjct: 878 MDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNL 937 Query: 534 RDRTGEQDVSQAAQDGSAESSYVQS 608 R E Q +D S Q+ Sbjct: 938 LSRAEEAKKEQVEEDNEVSSGLKQN 962 Score = 41.6 bits (96), Expect = 0.002 Identities = 48/223 (21%), Positives = 95/223 (42%), Gaps = 27/223 (12%) Frame = +3 Query: 24 LKEQLHEREKYILELEMKLNDTHRELDTLKI--DHQAVWANQ---------------DLL 152 +K+QL E+E++I L+ +L+ T E ++ + A + Q D+ Sbjct: 188 MKQQLQEKEEFISTLQAQLSQTQAEQAAQQVVREKDARFETQVRLHEDELLQLVTQADVE 247 Query: 153 REQTNEIASFRRELDNSEAERAQHLKQIHDLQEHL--REKESQYLALEEQHRVAQDNILY 326 E ++ +R+L+ E + + LQ+ L E+ +Q L+ + Q A+ N L Sbjct: 248 TEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLR 307 Query: 327 KD-EQLRDAHAWITRVQEMDI----LQSQSLQAELRERTDQF---GQCWATFQQQYVEMQ 482 E R+ + E+++ L +LQ E+ +QF GQ A + +Y ++ Sbjct: 308 NTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALE 367 Query: 483 QGFLHTIQRLQLELIELRDRTGEQDVSQAAQDGSAESSYVQSK 611 Q ++ ++ L+ +TG++ S S +Q K Sbjct: 368 QKHKAEMEEKTSHILSLQ-KTGQELQSACDALKDQNSKLLQDK 409 Score = 38.1 bits (87), Expect = 0.023 Identities = 44/184 (23%), Positives = 78/184 (42%), Gaps = 5/184 (2%) Frame = +3 Query: 24 LKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTN-EIASFRRELDN 200 L+++L E+ L +L E +TL+ + +L E+ E+A + N Sbjct: 278 LQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHN 337 Query: 201 SEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQE- 377 + E L+Q + E ES+Y ALE++H+ + K + +Q Sbjct: 338 LQEEMHHLLEQFEQAGQAQAELESRYSALEQKHKAEMEE---KTSHILSLQKTGQELQSA 394 Query: 378 MDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQ---GFLHTIQRLQLELIELRDRTG 548 D L+ Q+ + L+++ +Q Q T QQ ++QQ + RL L+ E +T Sbjct: 395 CDALKDQNSKL-LQDKNEQAVQSAQTIQQLEDQLQQKSKEISQFLNRLPLQQHETASQTS 453 Query: 549 EQDV 560 DV Sbjct: 454 FPDV 457 Score = 37.0 bits (84), Expect = 0.051 Identities = 32/108 (29%), Positives = 53/108 (49%), Gaps = 9/108 (8%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTN-------EIA 176 EK KEQ E I + E + ++ + L+ D QA L E+ N + Sbjct: 2329 EKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLL 2388 Query: 177 SFRRE-LDNSEAE-RAQHLKQIHDLQEHLREKESQYLALEEQHRVAQD 314 S + E + + AE R QH K+I +L+ L ++E + + LEE+++ A D Sbjct: 2389 SGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVD 2436 Score = 36.6 bits (83), Expect = 0.066 Identities = 37/157 (23%), Positives = 74/157 (47%), Gaps = 21/157 (13%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRE---LDTLKIDHQAVWANQDLLREQTNEIASFRR 188 EK+K +L E+E+ I L+ +L E + +++ + Q L+E+ I++ + Sbjct: 147 EKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQ--LQEKEEFISTLQA 204 Query: 189 ELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILY----------KDEQ 338 +L ++AE+A Q+ +REK++++ E Q R+ +D +L ++ Sbjct: 205 QLSQTQAEQA--------AQQVVREKDARF---ETQVRLHEDELLQLVTQADVETEMQQK 253 Query: 339 LR--------DAHAWITRVQEMDILQSQSLQAELRER 425 LR + + R Q +D+LQ + AE R + Sbjct: 254 LRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQ 290 Score = 36.2 bits (82), Expect = 0.087 Identities = 39/173 (22%), Positives = 77/173 (44%) Frame = +3 Query: 27 KEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDNSE 206 +E++H E+ I E+++ LN +E+ L Q+ L ++A+F + + + + Sbjct: 2150 REKVH-LEETIGEIQVTLNKKDKEVQQL----------QENLDSTVTQLAAFTKSMSSLQ 2198 Query: 207 AERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQEMDI 386 +R + I + ++ R+ + EE+ R+ +DN +QLR ++E+ I Sbjct: 2199 DDRD---RVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSI---HMEELKI 2252 Query: 387 LQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDRT 545 S R + Q W + Q V++QQ T+Q EL+ + T Sbjct: 2253 NIS---------RLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEET 2296 Score = 35.8 bits (81), Expect = 0.11 Identities = 46/214 (21%), Positives = 92/214 (42%), Gaps = 14/214 (6%) Frame = +3 Query: 9 VAAEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRR 188 +A E L E ++EK + E+E L + KI W + ++ EI Sbjct: 1574 LALEGLTE---DKEKLVKEIE--------SLKSSKIAESTEWQEKHKELQKEYEILLQSY 1622 Query: 189 ELDNSEAERAQHL-----KQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRD-A 350 E ++EAER QH+ ++ +L LR E+ E+Q + A+ + E++R A Sbjct: 1623 ENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFA 1682 Query: 351 HAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGF------LHTIQRL 512 + ++ E++ ++ L+AE+ D +C T M++ T+ + Sbjct: 1683 KSKQQKILELE-EENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKK 1741 Query: 513 QLELIELRDRTGE--QDVSQAAQDGSAESSYVQS 608 L+ +D E QD+ +D ++ + +++ Sbjct: 1742 FQSLMSEKDSLSEEVQDLKHQIEDNVSKQANLEA 1775 Score = 31.2 bits (69), Expect = 2.8 Identities = 28/120 (23%), Positives = 54/120 (45%), Gaps = 8/120 (6%) Frame = +3 Query: 9 VAAEKLKEQLHEREKYILEL---EMKLNDTHREL-----DTLKIDHQAVWANQDLLREQT 164 + E L + + R+K EL ++ L+DT E D LK+ + + + + Sbjct: 2058 ITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMK 2117 Query: 165 NEIASFRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLR 344 + R L+ +E + HLK+ ++QE L + + LEE Q + KD++++ Sbjct: 2118 QKDEDLERRLEQAEEK---HLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQ 2174
>KTN1_CHICK (Q90631) Kinectin| Length = 1364 Score = 44.3 bits (103), Expect = 3e-04 Identities = 40/156 (25%), Positives = 78/156 (50%), Gaps = 14/156 (8%) Frame = +3 Query: 9 VAAEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDL--------LREQT 164 V AE+L + + E++K + ++E L + H L T K + V N +L L+ T Sbjct: 594 VLAEELHKVIAEKDKQLKQMEDSLGNEHANL-TSKEEELKVLQNMNLSLKSEIQKLQALT 652 Query: 165 NEIASFRRELDNSEAERAQHLK--QIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQ 338 NE A+ EL+ + ++ H+K +I L+E LRE+ +Q + +E+ ++ +D + Sbjct: 653 NEQAAAAHELERMQ--KSIHIKDDKIRTLEEQLREELAQTVNTKEEFKILKDQNKTLQAE 710 Query: 339 LRDAHAWITRVQEMDILQSQSLQAE----LRERTDQ 434 ++ A ++ + ++ L E +RER D+ Sbjct: 711 VQKLQALLSEPVQPTFEANKDLLEEMERGMRERDDK 746
>MYH11_HUMAN (P35749) Myosin-11 (Myosin heavy chain, smooth muscle isoform)| (SMMHC) Length = 1972 Score = 44.3 bits (103), Expect = 3e-04 Identities = 45/165 (27%), Positives = 78/165 (47%), Gaps = 15/165 (9%) Frame = +3 Query: 15 AEKLKEQLHEREKYILELEMKLNDTHRELDTL--KIDHQAVWANQDL--LREQTNEIASF 182 A EQ+ + + I EL+M+L EL ++D + N L +RE I+ Sbjct: 1064 ASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDL 1123 Query: 183 RRELDNSEAERAQHLKQIHDLQEHLREKESQY------LALEEQHRVAQD---NILYK-- 329 + +LD+ A R + KQ DL E L +++ A +++ R ++ +L K Sbjct: 1124 QEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKAL 1183 Query: 330 DEQLRDAHAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQ 464 DE+ R A +VQEM +Q+++ EL E+ +QF + A + Sbjct: 1184 DEETRSHEA---QVQEMRQKHAQAVE-ELTEQLEQFKRAKANLDK 1224 Score = 40.8 bits (94), Expect = 0.004 Identities = 30/140 (21%), Positives = 70/140 (50%), Gaps = 4/140 (2%) Frame = +3 Query: 27 KEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTN---EIASFRRELD 197 +E++ +E + + + + EL L+ H + ++LL+EQ E+ + E+ Sbjct: 851 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 910 Query: 198 NSEAERAQHLKQI-HDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQ 374 A + Q L++I H+++ L E+E + L+ + + +L +EQL + A ++Q Sbjct: 911 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 970 Query: 375 EMDILQSQSLQAELRERTDQ 434 L+ + +A++++ D+ Sbjct: 971 ----LEKVTAEAKIKKLEDE 986 Score = 39.7 bits (91), Expect = 0.008 Identities = 35/149 (23%), Positives = 64/149 (42%), Gaps = 7/149 (4%) Frame = +3 Query: 18 EKLKEQLHEREKYILE---LEMKLNDTHRELDTLKIDHQAVWANQDLLREQ----TNEIA 176 E+L+E+ R+K LE E K+ E+ + + + + LL E+ T +A Sbjct: 957 EQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLA 1016 Query: 177 SFRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHA 356 + N + +H I +L+ L+++E LE+ R + + EQ+ D A Sbjct: 1017 EEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQA 1076 Query: 357 WITRVQEMDILQSQSLQAELRERTDQFGQ 443 I ++ + + LQA L D+ Q Sbjct: 1077 QIAELKMQLAKKEEELQAALARLDDEIAQ 1105 Score = 34.3 bits (77), Expect = 0.33 Identities = 35/132 (26%), Positives = 59/132 (44%), Gaps = 25/132 (18%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELD 197 +K KE+ + E + ELE K + E + L+ QA E +A+ ++EL+ Sbjct: 862 QKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELE 921 Query: 198 NS------------------EAERAQHLKQIHDLQEHLREKES--QYLALEE-----QHR 302 +AER + +Q+ DL+E L E+E+ Q L LE+ + + Sbjct: 922 EILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIK 981 Query: 303 VAQDNILYKDEQ 338 +D IL D+Q Sbjct: 982 KLEDEILVMDDQ 993
>MYSP_DERFA (Q967Z0) Paramyosin (Allergen Der f 11) (Antigen Df642) (Fragment)| Length = 692 Score = 44.3 bits (103), Expect = 3e-04 Identities = 45/202 (22%), Positives = 89/202 (44%), Gaps = 29/202 (14%) Frame = +3 Query: 18 EKLKEQ----LHEREKY---ILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIA 176 EKL++Q E +K + E + +LND HR + +I+ + + +D L E Sbjct: 327 EKLRDQRDQLARENKKLTDDLAEAKSQLNDAHRRIHEQEIEIKRLENERDELSAAYKEAE 386 Query: 177 SFRRELDNSEAERAQHLKQI-HDLQEHLREKESQYLALEEQH---------RVAQDNILY 326 + R++ + L Q+ HD ++ L +K+ + AL +Q+ R+A+ Sbjct: 387 TLRKQEEAKNQRLIAELAQVRHDYEKRLAQKDEEIEALRKQYQIEIEQLNMRLAEAEAKL 446 Query: 327 KDEQLRDAHAWITRVQEMDILQSQS------LQAELRERTDQFGQCWATFQQQYVEMQQG 488 K E R + ++ E+++ + LQ ++++ Q + A + + + ++QQ Sbjct: 447 KTEIARLKKKYQAQITELELSLDAANKANIDLQKTIKKQALQITELQAHYDEVHRQLQQA 506 Query: 489 F------LHTIQRLQLELIELR 536 Q LQ EL E+R Sbjct: 507 VDQLGVTQRRCQALQAELEEMR 528 Score = 35.4 bits (80), Expect = 0.15 Identities = 41/189 (21%), Positives = 79/189 (41%), Gaps = 14/189 (7%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKID-HQAVWANQDLLREQTNEIASFRREL 194 E + +L E E+ LE + EL++LK+ + A +L R+ T Sbjct: 151 EDTRHRLEEEERKRASLENHAHTLEVELESLKVQLDEESEARLELERQLTKANGDAASWK 210 Query: 195 DNSEAERAQHLKQIHDLQEHLREKESQY-----------LALEEQHRVAQD--NILYKDE 335 EAE H ++ +L+ + +K S+Y +LE+Q Q +L D Sbjct: 211 SKYEAELQAHADEVEELRRKMAQKISEYEEQLEALLNKCSSLEKQKSRLQSEVEVLIMDL 270 Query: 336 QLRDAHAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQ 515 + HA + E + Q + + +L+ + ++ +Q + + + +Q+LQ Sbjct: 271 EKATRHA---QQLEKRVAQLEKINLDLKNKLEEV----TMLMEQAQKELRVKIAELQKLQ 323 Query: 516 LELIELRDR 542 E +LRD+ Sbjct: 324 HEYEKLRDQ 332
>RRBP1_CANFA (Q28298) Ribosome-binding protein 1 (180 kDa ribosome receptor) (RRp)| Length = 1534 Score = 43.9 bits (102), Expect = 4e-04 Identities = 47/211 (22%), Positives = 97/211 (45%), Gaps = 8/211 (3%) Frame = +3 Query: 12 AAEKLKEQLHEREKYILE-LEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRR 188 A EK QL K E L+ +L++ REL + H ++ A+ + +EQ ++A Sbjct: 993 ALEKQVLQLQASHKESEEALQKRLDEVSRELCRSQTSHASLRADAEKAQEQQQQMAELHS 1052 Query: 189 ELDNSEAE---RAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAW 359 +L +SEAE +++ L +H + R + SQ + E++R A Sbjct: 1053 KLQSSEAEVKSKSEELSGLHGQLKEARAENSQLM-----------------ERIRSIEAL 1095 Query: 360 ITRVQEMDILQSQSLQAELRERTDQF-GQCWATFQQQYVEMQQGFLHTIQRLQLELIELR 536 + Q D +Q+ +AE + R + Q W +++ E+++ +++ +++ +LR Sbjct: 1096 LEAGQARDTQDAQASRAEHQARLKELESQVWC-LEKEATELKE----AVEQQKVKNNDLR 1150 Query: 537 DRTGEQDVSQAAQDGSAES---SYVQSKGSS 620 ++ + + A+ + + E S Q+K S Sbjct: 1151 EKNWKAMEALASAERACEEKLRSLTQAKEES 1181 Score = 33.5 bits (75), Expect = 0.56 Identities = 39/194 (20%), Positives = 80/194 (41%), Gaps = 8/194 (4%) Frame = +3 Query: 21 KLKEQLHEREKYILELEMKLNDTHRE--LDTLKIDHQAVWANQDLLREQTNEIASFRREL 194 K+K+QL RE+ I ++ ++ ++RE + ++ + + L ++A ++E Sbjct: 875 KVKKQLVAREQEITAVQARIEASYREHVKEVQQLQGKIRTLQEQLENGPNTQLARLQQEN 934 Query: 195 DNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQ 374 Q Q+ Q K Q L+ + V + ++EQ R A T Sbjct: 935 SILRDALNQATSQVESKQNTELAKLRQELSKVSKELVEKSEAARQEEQQRKALETKTAAL 994 Query: 375 EMDILQSQSLQAE----LRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDR 542 E +LQ Q+ E L++R D+ + Q + ++ Q Q ++ EL + Sbjct: 995 EKQVLQLQASHKESEEALQKRLDEVSRELCRSQTSHASLRAD-AEKAQEQQQQMAELHSK 1053 Query: 543 --TGEQDVSQAAQD 578 + E +V +++ Sbjct: 1054 LQSSEAEVKSKSEE 1067
>EP15_HUMAN (P42566) Epidermal growth factor receptor substrate 15 (Protein| Eps15) (AF-1p protein) Length = 896 Score = 43.9 bits (102), Expect = 4e-04 Identities = 45/181 (24%), Positives = 84/181 (46%), Gaps = 8/181 (4%) Frame = +3 Query: 93 RELDTLKIDHQAVWANQDLLREQTNEIASFRRELDNSEAERAQHLKQIHDLQEHLREKES 272 +ELDTL +++ V DL RE+ N ++L E Q ++ DLQ+ ++ + + Sbjct: 333 KELDTL--NNEIV----DLQREKNN----VEQDLKEKEDTIKQRTSEVQDLQDEVQRENT 382 Query: 273 QYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQEMDILQSQ---SLQAELRERTDQFGQ 443 L+ Q + Q+ + DEQ + V++ ++Q SL+AEL + Q Sbjct: 383 NLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQI-- 440 Query: 444 CWATFQQQYVEMQQGFLHTIQRLQLELIELRD-----RTGEQDVSQAAQDGSAESSYVQS 608 +T++++ + ++ + RLQ E EL + + + + Q QD E S +Q Sbjct: 441 --STYEEELAKARE----ELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQM 494 Query: 609 K 611 K Sbjct: 495 K 495
>MYH11_CHICK (P10587) Myosin-11 (Myosin heavy chain, gizzard smooth muscle)| Length = 1978 Score = 43.9 bits (102), Expect = 4e-04 Identities = 42/185 (22%), Positives = 88/185 (47%), Gaps = 7/185 (3%) Frame = +3 Query: 6 VVAAEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIA--- 176 V + + + + +HE EK LE ++ + +L+ L+ + QA A LR + N A Sbjct: 1522 VSSKDDVGKNVHELEKSKRTLEQQVEEMKTQLEELEDELQA--AEDAKLRLEVNMQAMKS 1579 Query: 177 SFRREL----DNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLR 344 F R+L + +E +R Q LKQ+H+ + L ++ Q + + ++ + Q+ Sbjct: 1580 QFERDLQARDEQNEEKRRQLLKQLHEHETELEDERKQRALAAAAKKKLEVDVKDLESQVD 1639 Query: 345 DAHAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLEL 524 A+ + +E I Q + LQA++++ A ++ + ++ + L+ EL Sbjct: 1640 SAN----KAREEAIKQLRKLQAQMKDYQRDLDDARAAREEIFATAREN-EKKAKNLEAEL 1694 Query: 525 IELRD 539 I+L++ Sbjct: 1695 IQLQE 1699 Score = 37.0 bits (84), Expect = 0.051 Identities = 25/120 (20%), Positives = 60/120 (50%), Gaps = 4/120 (3%) Frame = +3 Query: 27 KEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTN---EIASFRRELD 197 +E++ +++ + + + EL L+ H + ++LL+E+ E+ + E+ Sbjct: 856 EEEMQAKDEELQRTKERQQKAEAELKELEQKHTQLCEEKNLLQEKLQAETELYAEAEEMR 915 Query: 198 NSEAERAQHLKQI-HDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQ 374 A + Q L++I H+++ + E+E + L+ + + Q +L +EQL + A ++Q Sbjct: 916 VRLAAKKQELEEILHEMEARIEEEEERSQQLQAEKKKMQQQMLDLEEQLEEEEAARQKLQ 975 Score = 34.7 bits (78), Expect = 0.25 Identities = 32/149 (21%), Positives = 64/149 (42%), Gaps = 7/149 (4%) Frame = +3 Query: 18 EKLKEQLHEREKYILE---LEMKLNDTHRELDTLKIDHQAVWANQDLLREQ----TNEIA 176 E+L+E+ R+K LE + K+ ++ ++ + + + LL E+ T +A Sbjct: 962 EQLEEEEAARQKLQLEKVTADGKIKKMEDDILIMEDQNNKLTKERKLLEERVSDLTTNLA 1021 Query: 177 SFRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHA 356 + N + +H I +L+ L+++E LE+ R + EQ+ + A Sbjct: 1022 EEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKIKRKLEGESSDLHEQIAELQA 1081 Query: 357 WITRVQEMDILQSQSLQAELRERTDQFGQ 443 I ++ + + LQA L D+ Q Sbjct: 1082 QIAELKAQLAKKEEELQAALARLEDETSQ 1110
>NUMA1_HUMAN (Q14980) Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H| antigen) Length = 2115 Score = 43.5 bits (101), Expect = 5e-04 Identities = 39/199 (19%), Positives = 89/199 (44%), Gaps = 13/199 (6%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEI-ASFRREL 194 E +++ HE + + ELE++L ++ + + V +D L+EQ + S + Sbjct: 660 ETARQEQHEAQAQVAELELQLRSEQQK----ATEKERVAQEKDQLQEQLQALKESLKVTK 715 Query: 195 DNSEAERAQHLKQIHDLQEHLREKESQYLALEEQH----------RVAQDNILYKDEQLR 344 + E E+ + + + Q + E +++ +L EQH R + + + +QL Sbjct: 716 GSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLG 775 Query: 345 DAHAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLEL 524 +AH T V ++ ++ + Q +Q + A ++++Y + QQ Q +L Sbjct: 776 EAHQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQL 835 Query: 525 IELRD--RTGEQDVSQAAQ 575 + L++ Q++ +A + Sbjct: 836 MTLKEECEKARQELQEAKE 854 Score = 37.4 bits (85), Expect = 0.039 Identities = 35/137 (25%), Positives = 62/137 (45%), Gaps = 4/137 (2%) Frame = +3 Query: 15 AEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRREL 194 A++L+ QL+E + + + E +++ K + A L+EQ + ++E Sbjct: 1586 AQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQLQKEN 1645 Query: 195 D--NSEAERAQHLKQIHDLQEHLREKESQYLA--LEEQHRVAQDNILYKDEQLRDAHAWI 362 +EAER H Q Q L+ KE++ L Q R + + + D+QLRD + Sbjct: 1646 KELRAEAERLGHELQ----QAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQ 1701 Query: 363 TRVQEMDILQSQSLQAE 413 D L+S+ QA+ Sbjct: 1702 VAT---DALKSREPQAK 1715 Score = 33.5 bits (75), Expect = 0.56 Identities = 32/144 (22%), Positives = 68/144 (47%), Gaps = 4/144 (2%) Frame = +3 Query: 12 AAEKLKEQLHEREKYILELEMKLNDTHRELD----TLKIDHQAVWANQDLLREQTNEIAS 179 AAE+ + L ER+ + +LE + +L+ L++ ++A + Q + + E A Sbjct: 588 AAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAE 647 Query: 180 FRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAW 359 R+++ +A ++ H+ Q + E E Q L E+Q ++ + + +QL++ Sbjct: 648 LSRKVEELQACVETARQEQHEAQAQVAELELQ-LRSEQQKATEKERVAQEKDQLQEQ--- 703 Query: 360 ITRVQEMDILQSQSLQAELRERTD 431 + ++E + SL+ E R D Sbjct: 704 LQALKESLKVTKGSLEEEKRRAAD 727 Score = 33.5 bits (75), Expect = 0.56 Identities = 45/219 (20%), Positives = 95/219 (43%), Gaps = 23/219 (10%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQ------------ 161 E L+ + ++E +L + ++L +L D Q+ +N +E+ Sbjct: 437 EMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARL 496 Query: 162 TNEIASFRRELDNSEAERAQHLKQIHDLQEHLREKESQYL-ALEEQHRVAQ--------- 311 T ++AS EL A Q +++ L++ +EK++Q L++Q + +Q Sbjct: 497 TAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQL 556 Query: 312 -DNILYKDEQLRDAHAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQG 488 ++ K++QL++ A D Q + AE RE + + A Q + +E ++ Sbjct: 557 SSSLKQKEQQLKEV-AEKQEATRQDHAQQLATAAEEREASLRERDA-ALKQLEALEKEKA 614 Query: 489 FLHTIQRLQLELIELRDRTGEQDVSQAAQDGSAESSYVQ 605 I + QL++ + + V+QA ++ + S V+ Sbjct: 615 AKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVE 653 Score = 30.4 bits (67), Expect = 4.8 Identities = 30/144 (20%), Positives = 63/144 (43%), Gaps = 11/144 (7%) Frame = +3 Query: 21 KLKEQLHEREKYILELEMKLN-------DTHRELDTLKID----HQAVWANQDLLREQTN 167 KL++Q ++++ LE L + L+TL+ Q + +Q L Sbjct: 1131 KLEQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQR 1190 Query: 168 EIASFRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRD 347 E+A+FR ++ + + Q+ ++ K S +LEE+ + +L K+ + ++ Sbjct: 1191 ELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKE 1250 Query: 348 AHAWITRVQEMDILQSQSLQAELR 419 + R+ + +SQ L+ LR Sbjct: 1251 ----LKRLVMAESEKSQKLEERLR 1270
>MAD1_CANGA (Q6FS63) Spindle assembly checkpoint component MAD1 (Mitotic arrest| deficient protein 1) Length = 657 Score = 43.1 bits (100), Expect = 7e-04 Identities = 39/183 (21%), Positives = 85/183 (46%), Gaps = 15/183 (8%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKID-----HQAVWANQDLLREQTNEIASF 182 +K +E + ++ + I E++ L +ELD ++++ H A N + +R+QTNE ASF Sbjct: 156 KKYEEVIEQQSEQIKEIKKTLKKKEQELDEIEVNRLKQAHNAT--NTEEIRQQTNENASF 213 Query: 183 RRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWI 362 N+ + + + L +K S+Y + +Q + AQ I+ L + + ++ Sbjct: 214 SNGY-NTLMSMKNSVNYWKNENQQLNQKLSEYSDIYQQLQEAQLEIMELKANLEEWNKFL 272 Query: 363 TRVQEMD----------ILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRL 512 + ++ D I++ +S + EL T++ + ++ + + L Q L Sbjct: 273 SNKKQQDNSNDYSIDHFIIEFESQRRELNMVTEELAEVKKSYYNSKILNDELALERNQLL 332 Query: 513 QLE 521 +L+ Sbjct: 333 KLK 335
>CCD46_HUMAN (Q8N8E3) Coiled-coil domain-containing protein 46| Length = 955 Score = 43.1 bits (100), Expect = 7e-04 Identities = 44/212 (20%), Positives = 89/212 (41%), Gaps = 16/212 (7%) Frame = +3 Query: 3 HVVAAEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASF 182 H ++A K + E E+ + +L+ +L ++ + + LR+Q N+ Sbjct: 495 HALSASKASSMIEELEQNVCQLKQQLQESELQ-------------RKQQLRDQENKFQME 541 Query: 183 RRELDNSEAERAQHL------------KQIHDLQEHLREKESQYLALEEQHRVAQDNILY 326 + L + ++A L K+IH +E L+EKE Q + E R+ Sbjct: 542 KSHLKHIYEKKAHDLQSELDKGKEDTQKKIHKFEEALKEKEEQLTRVTEVQRL------- 594 Query: 327 KDEQLRDAHAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTI- 503 Q + A A + + L S+ + AE++E+ ++ + + + FL + Sbjct: 595 ---QAQQADAALEEFKRQVELNSEKVYAEMKEQMEKVEADLTRSKSLREKQSKEFLWQLE 651 Query: 504 ---QRLQLELIELRDRTGEQDVSQAAQDGSAE 590 QR + +++EL+ EQ+ + Q +AE Sbjct: 652 DIRQRYEQQIVELK-LEHEQEKTHLLQQHNAE 682
>MYSP_SARSC (Q9BMM8) Paramyosin| Length = 876 Score = 42.7 bits (99), Expect = 0.001 Identities = 45/202 (22%), Positives = 88/202 (43%), Gaps = 29/202 (14%) Frame = +3 Query: 18 EKLKEQ----LHEREKY---ILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIA 176 EKL++Q E +K + E + +LND HR + +I+ + + ++ L E Sbjct: 413 EKLRDQRDALARENKKLTDDLAECKSQLNDAHRRIHEQEIEIKRLENEREELSAAYKEAE 472 Query: 177 SFRRELDNSEAERAQHLKQI-HDLQEHLREKESQYLALEEQH---------RVAQDNILY 326 + R++ + L Q+ HD ++ L +KE + AL +Q+ R+A+ Sbjct: 473 TLRKQEEAKNQRLTAELAQVRHDYEKRLAQKEEEIEALRKQYQIEIEQLNMRLAEAEAKL 532 Query: 327 KDEQLRDAHAWITRVQEMDILQSQS------LQAELRERTDQFGQCWATFQQQYVEMQQG 488 K E R + ++ E+++ + LQ ++++ Q + A + + + ++QQ Sbjct: 533 KTEIARLKKKYQAQITELELSLDAANKANIDLQKTIKKQALQITELQAHYDEVHRQLQQA 592 Query: 489 F------LHTIQRLQLELIELR 536 Q LQ EL E R Sbjct: 593 VDQLGVTQRRCQALQAELEEQR 614 Score = 39.3 bits (90), Expect = 0.010 Identities = 41/189 (21%), Positives = 78/189 (41%), Gaps = 14/189 (7%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKID-HQAVWANQDLLREQTNEIASFRREL 194 E K +L E E+ LE + EL++LK+ + A +L R+ T Sbjct: 237 EDTKHRLEEEERKRASLENHAHTLEVELESLKVQLDEESEARLELERQLTKANGDAASWK 296 Query: 195 DNSEAERAQHLKQIHDLQEHLREKESQY-------------LALEEQHRVAQDNILYKDE 335 EAE H ++ +L+ + +K S+Y LA ++ ++ +L D Sbjct: 297 SKYEAELQAHADEVEELRRKMAQKISEYEEQLEALLNKCSSLAKQKSRLQSEVEVLIMDL 356 Query: 336 QLRDAHAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQ 515 + HA + E + Q + L +L+ + ++ +Q + + +Q+LQ Sbjct: 357 EKATTHA---QQLEKRVAQLEKLNLDLKNKLEEV----TMLMEQAQKEARAKAAELQKLQ 409 Query: 516 LELIELRDR 542 E +LRD+ Sbjct: 410 HEYEKLRDQ 418
>AKAP9_HUMAN (Q99996) A-kinase anchor protein 9 (Protein kinase A-anchoring| protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Hyperion protein) (Yotiao protei Length = 3911 Score = 42.7 bits (99), Expect = 0.001 Identities = 54/253 (21%), Positives = 103/253 (40%), Gaps = 54/253 (21%) Frame = +3 Query: 27 KEQLHEREKYILELEMKLNDTHRELDT-----------------LKIDHQAVWANQ---- 143 +EQ+ + I E E KLN+ H+ L T L++ H+A N Sbjct: 553 REQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKL 612 Query: 144 DLLREQTNEIASFRRELDNSEAERAQ------HLKQIHDLQEHLR-------EKESQYLA 284 ++L ++ N + E +E ER + H +++ L+E L EK L Sbjct: 613 EMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLG 672 Query: 285 LEEQHRV----------------AQDNILYKDEQLRDAHAWITRVQEMDILQSQSLQAEL 416 + + ++ +DN++ K QL I + ++ LQ + ++ Sbjct: 673 IHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQL------ILEISKLKDLQQSLVNSKS 726 Query: 417 RERTDQFGQCWATFQ-QQYVEMQQGFL-HTIQRLQL--ELIELRDRTGEQDVSQAAQDGS 584 E T Q + + + E ++G L +Q LQL EL+E + + E D+ + Sbjct: 727 EEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLE 786 Query: 585 AESSYVQSKGSSM 623 AE+S ++ + ++ Sbjct: 787 AENSILKDEKKTL 799 Score = 35.0 bits (79), Expect = 0.19 Identities = 30/124 (24%), Positives = 56/124 (45%), Gaps = 19/124 (15%) Frame = +3 Query: 27 KEQLHEREKYILELEMKLNDTHR-------------------ELDTLKIDHQAVWANQDL 149 KEQ+ EK +LE E KL + + +++ LK + +N++ Sbjct: 2638 KEQVEIAEKNVLEKEKKLLELQKLLEGNEKKQREKEKKRSPQDVEVLKTTTELFHSNEE- 2696 Query: 150 LREQTNEIASFRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYK 329 NE+ + R E ++AE A + ++ LQE L KE+ +L++ +D++ Sbjct: 2697 -SGFFNELEALRAESVATKAELASYKEKAEKLQEELLVKETNMTSLQKDLSQVRDHLAEA 2755 Query: 330 DEQL 341 E+L Sbjct: 2756 KEKL 2759 Score = 34.3 bits (77), Expect = 0.33 Identities = 40/181 (22%), Positives = 79/181 (43%), Gaps = 4/181 (2%) Frame = +3 Query: 27 KEQLHEREKYILELEMKLNDTHREL----DTLKIDHQAVWANQDLLREQTNEIASFRREL 194 KE++ E+E I EL K+ + ++ D L + + Q+ + ++ EI + + EL Sbjct: 333 KEEIQEKETIIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLEL 392 Query: 195 DNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQ 374 NS+ + Q ++I L + E + + +KD Q + R++ Sbjct: 393 TNSKQKERQSSEEIKQLMGTVEELQKRN---------------HKDSQFET--DIVQRME 435 Query: 375 EMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDRTGEQ 554 + + + L+AEL E + QQ V+M+Q + Q+E ++ R + GE Sbjct: 436 QETQRKLEQLRAELDE----------MYGQQIVQMKQELIRQ-HMAQMEEMKTRHK-GEM 483 Query: 555 D 557 + Sbjct: 484 E 484 Score = 29.6 bits (65), Expect = 8.1 Identities = 37/191 (19%), Positives = 79/191 (41%), Gaps = 8/191 (4%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELD 197 E+L E+ RE+ +EL D + + + D++ E+ L Sbjct: 1913 ERLHEESRAREQLAVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCASNRLQ 1972 Query: 198 NSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQE 377 EAE+ Q +++ +L +E EQ + + L K++ + +V++ Sbjct: 1973 ELEAEQ-QQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEK--LEVQCQAEKVRD 2029 Query: 378 MDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELR------- 536 Q ++L+ ++ E+ +F + + ++++Q Q L+ +L ++R Sbjct: 2030 DLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQ----QNQALEKQLEKMRKFLDEQA 2085 Query: 537 -DRTGEQDVSQ 566 DR E+DV Q Sbjct: 2086 IDREHERDVFQ 2096
>MYH10_RAT (Q9JLT0) Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle| myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B) Length = 1976 Score = 42.4 bits (98), Expect = 0.001 Identities = 30/140 (21%), Positives = 73/140 (52%), Gaps = 4/140 (2%) Frame = +3 Query: 27 KEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTN---EIASFRRELD 197 +E+L +++ +L+++ K EL+ ++ HQ + +++L EQ E+ + E+ Sbjct: 851 EEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMR 910 Query: 198 NSEAERAQHLKQI-HDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQ 374 A + Q L++I HDL+ + +E + L+ + + Q +I +EQL + ++Q Sbjct: 911 ARLAAKKQELEEILHDLESRVEGEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQ 970 Query: 375 EMDILQSQSLQAELRERTDQ 434 L+ + +A++++ ++ Sbjct: 971 ----LEKVTAEAKIKKMEEE 986
>RRBP1_HUMAN (Q9P2E9) Ribosome-binding protein 1 (Ribosome receptor protein) (180| kDa ribosome receptor homolog) (ES/130-related protein) Length = 1410 Score = 42.4 bits (98), Expect = 0.001 Identities = 41/165 (24%), Positives = 71/165 (43%) Frame = +3 Query: 66 LEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDNSEAERAQHLKQIHDL 245 L+ +L++ REL + H ++ A+ + +EQ ++A +L +SEAE +++ L Sbjct: 880 LQKRLDEVSRELCHTQSSHASLRADAEKAQEQQQQMAELHSKLQSSEAEVRSKCEELSGL 939 Query: 246 QEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQEMDILQSQSLQAELRER 425 L+E ++ L E R+ L + Q RDA Q +QA E Sbjct: 940 HGQLQEARAENSQLTE--RIRSIEALLEAGQARDA---------------QDVQASQAEA 982 Query: 426 TDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDRTGEQDV 560 Q Q + E++ + L+ E IELR+ +Q V Sbjct: 983 DQQ--------QTRLKELES----QVSGLEKEAIELREAVEQQKV 1015 Score = 34.3 bits (77), Expect = 0.33 Identities = 45/214 (21%), Positives = 84/214 (39%), Gaps = 17/214 (7%) Frame = +3 Query: 21 KLKEQLHEREKYILELEMKLNDTHRE--LDTLKIDHQAVWANQDLLREQTNEIASFRREL 194 K+K+QL RE+ I ++ ++ ++RE + ++ + + L ++A ++E Sbjct: 743 KVKKQLVAREQEITAVQARMQASYREHVKEVQQLQGKIRTLQEQLENGPNTQLARLQQEN 802 Query: 195 DNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQ 374 Q Q+ Q K Q L+ + V + + +DEQ R A Sbjct: 803 SILRDALNQATSQVESKQNAELAKLRQELSKVSKELVEKSEAVRQDEQQRKALEAKAAAF 862 Query: 375 EMDILQSQSLQAE----LRERTDQFGQCWATFQQQYV----------EMQQGFLHTIQRL 512 E +LQ Q+ E L++R D+ + Q + E QQ +L Sbjct: 863 EKQVLQLQASHRESEEALQKRLDEVSRELCHTQSSHASLRADAEKAQEQQQQMAELHSKL 922 Query: 513 QLELIELRDRTGE-QDVSQAAQDGSAESSYVQSK 611 Q E+R + E + Q+ AE+S + + Sbjct: 923 QSSEAEVRSKCEELSGLHGQLQEARAENSQLTER 956
>EEA1_MOUSE (Q8BL66) Early endosome antigen 1| Length = 1411 Score = 42.4 bits (98), Expect = 0.001 Identities = 45/207 (21%), Positives = 84/207 (40%), Gaps = 29/207 (14%) Frame = +3 Query: 24 LKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDNS 203 L+ LH+R+ +L+ +L + L Q L E+ R EL Sbjct: 335 LQASLHQRDLDCQQLQARLTASESSLQRA----------QGELSEKAEAAQKLREELREV 384 Query: 204 EAERAQHLK-QIHDLQEHLREKESQYLALE-------------------------EQHRV 305 E+ R QHLK ++ LQ+ EKE L L+ EQ ++ Sbjct: 385 ESTR-QHLKVEVKQLQQQREEKEQHGLQLQGEVSQLHCKLLETERQLGEAHGRLKEQRQL 443 Query: 306 AQDNILYKDEQLRDAHAWITRVQEM---DILQSQSLQAELRERTDQFGQCWATFQQQYVE 476 + + ++ K++Q+ D ++R++E + S LQ +L + Q Q+ Sbjct: 444 SSEKLMEKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLEKSKQQ--------HQEQQA 495 Query: 477 MQQGFLHTIQRLQLELIELRDRTGEQD 557 +QQ ++ Q +L ++ + G++D Sbjct: 496 LQQSATAKLREAQNDLEQVLRQIGDKD 522 Score = 33.1 bits (74), Expect = 0.73 Identities = 40/212 (18%), Positives = 91/212 (42%), Gaps = 19/212 (8%) Frame = +3 Query: 12 AAEKLKEQLHEREKYILELEMKLNDTHREL---DTLKIDHQAVWAN-----QDLLREQTN 167 + +L QL+E ++ + +L++++ L + K +A N Q L+++ Sbjct: 622 SVSELSSQLNESKEKVSQLDIQIKAKTELLLSAEAAKAAQRADLQNHLDTAQHALQDKQQ 681 Query: 168 EIASFRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRD 347 E+ +LD A+ + + L+ HL++ + ++L+LE++ + +I + + Sbjct: 682 ELNKVSVQLDQLTAKFQEKQEHCIQLESHLKDHKEKHLSLEQKVEDLEGHIKKLEADALE 741 Query: 348 AHAWITRVQEMDILQSQ---SLQAELR--------ERTDQFGQCWATFQQQYVEMQQGFL 494 A ++ Q + LQ Q S ELR + ++ C Q E+ + Sbjct: 742 VKA--SKEQALQSLQQQRQLSTDLELRNAELSRELQEQEEVVSCTKLDLQNKSEILENIK 799 Query: 495 HTIQRLQLELIELRDRTGEQDVSQAAQDGSAE 590 T+ + + E + L+ Q+ + +QD + Sbjct: 800 QTLTKKEEENVVLK-----QEFEKLSQDSKTQ 826 Score = 33.1 bits (74), Expect = 0.73 Identities = 39/177 (22%), Positives = 76/177 (42%), Gaps = 11/177 (6%) Frame = +3 Query: 60 LELEMKLNDTHRELDTLKIDHQAVWANQDLLREQT----NEIASFRRELDNSEAERAQHL 227 LE E + E L+ +H + A + LR + E+A + +E+ + + Sbjct: 242 LERERESEKLKDECKKLQSEHAHLEATINQLRSELAKGPQEVAVYVQEIQKLKGSINELT 301 Query: 228 KQIHDLQEHLREKESQYLALEEQH-------RVAQDNILYKDEQLRDAHAWITRVQEMDI 386 ++ +L E L++K+ Y LEE+H + Q ++ +D + A +T + Sbjct: 302 QKNQNLTEKLQKKDLDYTHLEEKHNEESASRKTLQASLHQRDLDCQQLQARLTASES--- 358 Query: 387 LQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDRTGEQD 557 Q Q EL E+ A Q+ E + T Q L++E+ +L+ + E++ Sbjct: 359 -SLQRAQGELSEK--------AEAAQKLREELREVESTRQHLKVEVKQLQQQREEKE 406
>INVO_PONPY (P14708) Involucrin| Length = 835 Score = 42.0 bits (97), Expect = 0.002 Identities = 49/204 (24%), Positives = 91/204 (44%), Gaps = 21/204 (10%) Frame = +3 Query: 18 EKLKEQLHEREKYI---LELEMKLNDTHRELDTLKIDHQAVWANQDLLR---EQTNEIAS 179 ++LK++ +R++ + LE E KL D + + +K D Q + LL +Q + Sbjct: 106 QQLKQEKAQRDQQLNEQLEEEKKLLDQRLDQELVKRDEQLGMKKEQLLELPEQQEQHLKH 165 Query: 180 FRR-----ELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDE-QL 341 + EL + + +HL+Q +HL ++E Q EEQ V Q L + E QL Sbjct: 166 LEQQEGQLELPEQQEGQLKHLEQQEGQLKHLEQQEGQLEVPEEQ--VGQLKYLEQQEGQL 223 Query: 342 RDAHAWITRVQEMDILQSQ-----SLQAELRERTDQFGQCWATFQQ----QYVEMQQGFL 494 + +++ +D + Q + +L+ Q GQ QQ + E Q+G L Sbjct: 224 KHLDQQEGQLKHLDQQEGQLKHLDQQEGQLKHLDQQEGQLKHLDQQEGQLELPEQQEGQL 283 Query: 495 HTIQRLQLELIELRDRTGEQDVSQ 566 +++ + +L L G+ +V + Sbjct: 284 KHLEQQEGQLKHLEHEEGQLEVPE 307 Score = 34.3 bits (77), Expect = 0.33 Identities = 47/196 (23%), Positives = 83/196 (42%), Gaps = 23/196 (11%) Frame = +3 Query: 21 KLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRR---- 188 +L EQ + K++ + E +L + L++ + V L +Q ++ + Sbjct: 334 ELPEQQEGQLKHLEQQEGQLKHLEHQKGQLEVPEEQV-GQLKYLEQQEGQLKHLDQQEGQ 392 Query: 189 -ELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQ---------------HRVAQDNI 320 EL + + +HL+Q +HL +E Q EEQ H Q+ Sbjct: 393 LELPEQQEGQLKHLEQQEGQLKHLEHQEGQLEVPEEQVGQLKYLEQQEGQLKHLDQQEGQ 452 Query: 321 L-YKDEQLRDAHAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLH 497 L + D+Q + +V ++ L+ Q Q E+ E +Q GQ +Y+E Q+G L Sbjct: 453 LKHLDQQEKQLELPEQQVGQLKHLEQQEGQLEVPE--EQVGQL------KYLEQQEGQLK 504 Query: 498 TI--QRLQLELIELRD 539 + Q QLEL E ++ Sbjct: 505 HLDQQEGQLELPEQQE 520 Score = 32.7 bits (73), Expect = 0.96 Identities = 36/129 (27%), Positives = 58/129 (44%), Gaps = 12/129 (9%) Frame = +3 Query: 189 ELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDE-QLR-----DA 350 EL + + +HL+Q +HL +E Q EEQ V Q L + E QL+ + Sbjct: 274 ELPEQQEGQLKHLEQQEGQLKHLEHEEGQLEVPEEQ--VGQLKYLEQQEGQLKHLDQQEG 331 Query: 351 HAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQ----QYVEMQQGFLHTI--QRL 512 + QE + + + +L+ Q GQ +Q +Y+E Q+G L + Q Sbjct: 332 QLELPEQQEGQLKHLEQQEGQLKHLEHQKGQLEVPEEQVGQLKYLEQQEGQLKHLDQQEG 391 Query: 513 QLELIELRD 539 QLEL E ++ Sbjct: 392 QLELPEQQE 400 Score = 32.3 bits (72), Expect = 1.3 Identities = 39/135 (28%), Positives = 61/135 (45%), Gaps = 6/135 (4%) Frame = +3 Query: 189 ELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDE-QLRDAHAWIT 365 EL + + +HL+Q +HL +E Q EEQ V Q L + E QL+ Sbjct: 514 ELPEQQEGQLKHLEQQEGQLKHLEHQEGQLEVPEEQ--VGQLKYLEQQEGQLKHLDQQEG 571 Query: 366 RVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDRT 545 +++ +D Q Q EL E+ Q GQ +++E Q+G L ++ + +L L + Sbjct: 572 QLKHLD---QQEKQLELPEQ--QVGQL------KHLEQQEGQLEHLEGQEGQLEHLEHQE 620 Query: 546 G-----EQDVSQAAQ 575 G EQ V Q Q Sbjct: 621 GQLGLPEQQVWQLKQ 635 Score = 30.0 bits (66), Expect = 6.2 Identities = 32/130 (24%), Positives = 54/130 (41%), Gaps = 4/130 (3%) Frame = +3 Query: 189 ELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITR 368 EL + + +HL+Q EHL +E Q LE Q L + W + Sbjct: 584 ELPEQQVGQLKHLEQQEGQLEHLEGQEGQLEHLEHQE---------GQLGLPEQQVWQLK 634 Query: 369 VQEMDILQSQSLQAE---LRERTDQFGQC-WATFQQQYVEMQQGFLHTIQRLQLELIELR 536 E Q ++L+ E L+ Q GQ Q +++E Q G L ++ + +L L Sbjct: 635 QLEKQEGQPKNLEEEEGQLKHLVQQEGQLEQQEGQVEHLEEQVGQLKHLEEQEGQLKYLE 694 Query: 537 DRTGEQDVSQ 566 + G+ +V + Sbjct: 695 QQQGQLEVPE 704
>MYO1_YEAST (P08964) Myosin-1 (Type II myosin)| Length = 1928 Score = 41.6 bits (96), Expect = 0.002 Identities = 47/201 (23%), Positives = 95/201 (47%), Gaps = 8/201 (3%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELD 197 EKLK Q ++EK I E EM+ ND+ +L ++ + V QD+ + ++++A + L Sbjct: 1521 EKLKTQNKQKEKLIWEREMERNDSDMQLQETLLELKRV---QDVKKILSDDLAHLKERLS 1577 Query: 198 NSEAERAQHLKQIHDLQEHLR-------EKESQYLALEEQHRVAQDNILYKDEQLRDAHA 356 E +R+Q+ +I+ L+E L + ++ L+ + + ++ K L Sbjct: 1578 AVE-DRSQYTDEINRLKEELNCSLKAETNLKKEFATLKYKLETSTNDSEAKISDLLKQLD 1636 Query: 357 WITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLEL-IEL 533 T+V EM L ++ L E+ + Q + + E +G + ++ +++ EL +L Sbjct: 1637 HYTKVVEM--LNNEKDAISLAEK--ELYQKYEALNTE-CESLKGKIVSLTKIKQELESDL 1691 Query: 534 RDRTGEQDVSQAAQDGSAESS 596 +T +S AA S + + Sbjct: 1692 NQKTDALQISNAALSSSTQKN 1712 Score = 30.4 bits (67), Expect = 4.8 Identities = 28/118 (23%), Positives = 54/118 (45%), Gaps = 4/118 (3%) Frame = +3 Query: 33 QLHEREKYI-LELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDNSEA 209 ++HE E + LE ++K + E+ K +AV Q +QT+ I + E Sbjct: 1801 KIHELENMVSLETDLK----YEEMKKNKSLERAVEELQTKNSQQTDVIELANKNRSEFEE 1856 Query: 210 ERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKD---EQLRDAHAWITRVQ 374 ++ QI DL++++ ++E E + +DN Y+D E ++ W +R + Sbjct: 1857 ATLKYEAQISDLEKYISQQEL------EMKKSIRDNSSYRDKVQEMAQEIEFWKSRYE 1908
>HMW2_MYCPN (P75471) Cytadherence high molecular weight protein 2 (Cytadherence| accessory protein 2) Length = 1818 Score = 41.6 bits (96), Expect = 0.002 Identities = 48/211 (22%), Positives = 93/211 (44%), Gaps = 24/211 (11%) Frame = +3 Query: 15 AEKLKEQLHEREKYILELEMKLNDTHRELDT----LKIDHQAVWANQDLLREQTNEIASF 182 A+ L++Q +E E+ E +KL H++L KI+ +A + L Q E+ Sbjct: 365 AKHLEQQQYEFERKQQESLLKLETEHKQLQKRIGEFKIESEA---KSEALLIQERELLEK 421 Query: 183 RRELDN----------SEAERAQHLKQIH-DLQEHLR---------EKESQYLALEEQHR 302 RRE+D+ + Q LK+ H +Q+H + +++ YLA EQ R Sbjct: 422 RREIDDLLTQASLEYEQQRRTNQVLKEKHRQVQQHFQNLVHAKKKLDQKRHYLA--EQKR 479 Query: 303 VAQDNILYKDEQLRDAHAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQ 482 + ++ I E++ + ++ + + + +L Q Q A F+ + E Q Sbjct: 480 IDEEQIFKLKEKIATERRELEKLYLVKKQKQDQKENDLLIFEKQLRQYQADFENEIEEKQ 539 Query: 483 QGFLHTIQRLQLELIELRDRTGEQDVSQAAQ 575 + + LQ +L+++ E +++Q AQ Sbjct: 540 NELFASQKSLQKSFTQLKNK--EAELNQKAQ 568 Score = 31.2 bits (69), Expect = 2.8 Identities = 38/225 (16%), Positives = 102/225 (45%), Gaps = 21/225 (9%) Frame = +3 Query: 6 VVAAEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWAN-QDLLR-----EQTN 167 ++ +L E+ E + + + ++ R LK H+ V + Q+L+ +Q Sbjct: 412 LIQERELLEKRREIDDLLTQASLEYEQQRRTNQVLKEKHRQVQQHFQNLVHAKKKLDQKR 471 Query: 168 EIASFRRELDNSE--------AERAQHLKQIHDLQEHLRE-KESQYLALEEQHRVAQDNI 320 + ++ +D + A + L++++ +++ ++ KE+ L E+Q R Q + Sbjct: 472 HYLAEQKRIDEEQIFKLKEKIATERRELEKLYLVKKQKQDQKENDLLIFEKQLRQYQADF 531 Query: 321 LYKDEQLRDAHAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQ---QYVEMQ--- 482 + E+ ++ + + Q ++ +AEL ++ + + WA +Q + +++ Sbjct: 532 ENEIEEKQNELFASQKSLQKSFTQLKNKEAELNQKAQKIAEDWAHLKQNKHHHADLEIFL 591 Query: 483 QGFLHTIQRLQLELIELRDRTGEQDVSQAAQDGSAESSYVQSKGS 617 +G + +Q+ + +L+E R + + +A+ ++ V+ K S Sbjct: 592 EGEFNHLQQEKHKLLEARTQFDNRVSLLSARFKQKQAELVKQKQS 636
>MY18A_HUMAN (Q92614) Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain)| (Molecule associated with JAK3 N-terminus) (MAJN) Length = 2054 Score = 41.6 bits (96), Expect = 0.002 Identities = 44/208 (21%), Positives = 91/208 (43%), Gaps = 31/208 (14%) Frame = +3 Query: 21 KLKEQLHERE-------KYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIAS 179 +LK QL E E K +E+++ D H ++D + A+ L+ + NEI + Sbjct: 1687 QLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQN 1746 Query: 180 FRRELDNSE------------AERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNIL 323 R E D + A+ ++ L QI+DLQ L E + L+E+ + Q + Sbjct: 1747 -RLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVE 1805 Query: 324 YKDEQLRD---AHAWITRVQEMD---------ILQSQSLQAELRERTDQFGQCWATFQQQ 467 + ++ + D +++E++ + + +SL + L+E ++ + + Q Sbjct: 1806 FLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTE----ERDQ 1861 Query: 468 YVEMQQGFLHTIQRLQLELIELRDRTGE 551 + + +RLQ +L + ++ GE Sbjct: 1862 RIAAENREKEQNKRLQRQLRDTKEEMGE 1889 Score = 36.2 bits (82), Expect = 0.087 Identities = 44/205 (21%), Positives = 91/205 (44%), Gaps = 32/205 (15%) Frame = +3 Query: 39 HEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDL-----------LREQTNEIASFR 185 HE EK + +L+ H E K+ + + +D+ L E+ +IA F Sbjct: 1454 HELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFT 1513 Query: 186 RELDNSEAE--------------RAQHLKQIHDLQEHLREKESQYLALEEQH------RV 305 +++ + EAE A+ KQ+ DL+ ++++E + L+EQ Sbjct: 1514 QKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEE---LDEQAGTIQMLEQ 1570 Query: 306 AQDNILYKDEQLRDAHAWITRVQEMDILQS-QSLQAELRERTDQFGQCWATFQQQYVEMQ 482 A+ + + E++R H+ ++ ++ ++ QS Q +L++ Q +++Y E + Sbjct: 1571 AKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQ-------LEEEY-EDK 1622 Query: 483 QGFLHTIQRLQLELIELRDRTGEQD 557 Q L + L+ +L L D+ +D Sbjct: 1623 QKVLREKRELEGKLATLSDQVNRRD 1647
>YCF2_OENPI (P31568) Protein ycf2 (Fragment)| Length = 721 Score = 41.6 bits (96), Expect = 0.002 Identities = 34/140 (24%), Positives = 63/140 (45%), Gaps = 2/140 (1%) Frame = +3 Query: 9 VAAEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQD--LLREQTNEIASF 182 + AE++ E+ E + LE E+ + E + + + A Q+ LL E+ E+ Sbjct: 490 IPAEEIPEEEDELPEDALETEVAVWGVEEEGEADDEEDVLLEAQQEDELLEEEDEELDEE 549 Query: 183 RRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWI 362 ELD E E + ++H+ +E E+E + EE D+ ++ + + H WI Sbjct: 550 EDELDEEEEEPKEEEDELHEEEEEEEEEEEEE---EEDELQENDSEFFRVKPIIPRHRWI 606 Query: 363 TRVQEMDILQSQSLQAELRE 422 R ++ D+ + S E E Sbjct: 607 FR-KKKDVFEVLSYPEEATE 625
>CF060_HUMAN (Q8NB25) Protein C6orf60| Length = 1020 Score = 41.6 bits (96), Expect = 0.002 Identities = 38/159 (23%), Positives = 71/159 (44%), Gaps = 15/159 (9%) Frame = +3 Query: 3 HVVAAEKLKEQLHER-EKYILELEMKLNDTHRELDT----------LKIDHQAVWANQDL 149 H + LK+ E E + +E+E +L EL+ +++HQ A L Sbjct: 657 HSAELQSLKDAHRESMEGFRIEMEQELQTLRFELEDEGKAMLASLRSELNHQHAAAIDLL 716 Query: 150 LREQTNEIASFRREL----DNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDN 317 E+A+ + EL D S + +H+ +I DLQE LR +E L+++ + +N Sbjct: 717 RHNHHQELAAAKMELERSIDISRRQSKEHICRITDLQEELRHREHHISELDKEVQHLHEN 776 Query: 318 ILYKDEQLRDAHAWITRVQEMDILQSQSLQAELRERTDQ 434 I ++L I R++ Q + + +L +R ++ Sbjct: 777 ISALTKELEFKGKEILRIRSESNQQIRLHEQDLNKRLEK 815 Score = 34.7 bits (78), Expect = 0.25 Identities = 48/205 (23%), Positives = 91/205 (44%), Gaps = 8/205 (3%) Frame = +3 Query: 42 EREKYILELEMKLNDTHRELDTLKIDHQAVWAN-QDLLREQTNEI-ASFRRELDNSEAER 215 E+++ ILELE K+N+ R T + ++ N Q L E+ ++ + + L+ + Sbjct: 314 EQKQQILELEKKVNEAKR---TQQEYYERELKNLQSRLEEEVTQLNEAHSKTLEELAWKH 370 Query: 216 AQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQEMDILQS 395 ++ +H +R+K+ + LEEQH + N+ QL+ QE++ L+ Sbjct: 371 HMAIEAVH--SNAIRDKKKLQMDLEEQHNKDKLNLEEDKNQLQ---------QELENLK- 418 Query: 396 QSLQAELRERTDQFG--QCWATFQQQYVEMQQGFLHTIQ----RLQLELIELRDRTGEQD 557 + L+ +L + G Q +Q + +G + ++Q RLQ EL +D E Sbjct: 419 EVLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERLQNELDLTKDSLKETK 478 Query: 558 VSQAAQDGSAESSYVQSKGSSMACK 632 + +G E Q + + A K Sbjct: 479 DALLNVEGELEQERQQHEETIAAMK 503
>TAO1A_XENLA (Q6NU21) Serine/threonine-protein kinase TAO1-A (EC 2.7.11.1)| (Thousand and one amino acid protein 1-A) Length = 1001 Score = 41.6 bits (96), Expect = 0.002 Identities = 52/203 (25%), Positives = 99/203 (48%), Gaps = 28/203 (13%) Frame = +3 Query: 21 KLKEQLHE-REKYILELEMKLNDTHRELDTLKIDHQAVWANQ------DLLREQTNEIAS 179 KLK ++ E R + +LE + N+ E++ L HQA + D + Q + A Sbjct: 484 KLKAEMDEHRLRLDKDLETQRNNFSAEMEKLVKKHQAAMEKELKSIANDEKKFQQHIQAQ 543 Query: 180 FRRELDNS-EAERAQHLKQIHDLQEHLREKES-------QYLALEE---QHRVAQD--NI 320 ++EL+N E+++ ++ + L+E L E +S ++L+ ++ QH A++ N+ Sbjct: 544 QKKELNNFLESQKREYKLRKEQLKEELNENQSTPKKEKQEWLSKQKENFQHFQAEEEANL 603 Query: 321 LYKDEQLRDAHAWITRVQEMDILQSQS-----LQAELRERTDQFGQCWATFQQQYVEMQQ 485 L + Q D R + +L + ++ EL +R Q A +Q+ MQ+ Sbjct: 604 LRRQRQYLDLEC--RRFKRRMLLNRHNSEQDLVREELNKRQTQKDLEHAMLLRQHESMQE 661 Query: 486 ---GFLHTIQRLQLELIELRDRT 545 L+TIQ+++ ELI+L+ +T Sbjct: 662 LEFRHLNTIQKMRCELIKLQHQT 684
>YCF2_OENVI (P31569) Protein ycf2 (Fragment)| Length = 630 Score = 41.2 bits (95), Expect = 0.003 Identities = 34/140 (24%), Positives = 64/140 (45%), Gaps = 2/140 (1%) Frame = +3 Query: 9 VAAEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQD--LLREQTNEIASF 182 + AE++ E+ E + LE E+ + E + + + A Q+ LL E+ E+ Sbjct: 401 IPAEEIPEEEDELPEDALETEVAVWGVEEEGEADDEEDVLLEAQQEDELLEEEDEELDEE 460 Query: 183 RRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWI 362 ELD E E + ++H+ +E E+E + L+E D+ ++ + + H WI Sbjct: 461 EDELDEEEEEPKEEEDELHEEEEEEEEEEEEEDELQE-----NDSEFFRVKPIIPRHRWI 515 Query: 363 TRVQEMDILQSQSLQAELRE 422 R ++ D+ + S E E Sbjct: 516 FR-KKKDVFEVLSYPEEATE 534
>TAO1B_XENLA (Q7ZYJ0) Serine/threonine-protein kinase TAO1-B (EC 2.7.11.1)| (Thousand and one amino acid protein 1-B) Length = 1001 Score = 41.2 bits (95), Expect = 0.003 Identities = 53/205 (25%), Positives = 98/205 (47%), Gaps = 30/205 (14%) Frame = +3 Query: 21 KLKEQLHE-REKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELD 197 KLK ++ E R + +LE + N+ E++ L HQA + L+ NE F++ + Sbjct: 484 KLKAEMDEHRLRLDKDLETQRNNFAAEIEKLVKKHQAAMEKE--LKLMANEEKKFQQHIQ 541 Query: 198 -------NS--EAERAQHLKQIHDLQEHLREKES-------QYLALEE---QHRVAQD-- 314 NS E+++ ++ + L+E L E +S ++L+ ++ QH A++ Sbjct: 542 AQQKKELNSFLESQKREYKLRKEQLKEELNENQSTPKKEKQEWLSKQKENFQHFQAEEEA 601 Query: 315 NILYKDEQLRDAHAWITRVQEMDILQSQSLQA-----ELRERTDQFGQCWATFQQQYVEM 479 N+L + Q + R + +L +L+ EL +R Q A +Q+ M Sbjct: 602 NLLRRQRQYLELEC--RRFKRRMLLSRHNLEQDLVREELNKRQTQKDLEHAMLLRQHESM 659 Query: 480 QQ---GFLHTIQRLQLELIELRDRT 545 Q+ L+TIQR++ ELI+L+ +T Sbjct: 660 QELEFRHLNTIQRMRCELIKLQHQT 684
>CN145_HUMAN (Q6ZU80) Protein C14orf145| Length = 623 Score = 41.2 bits (95), Expect = 0.003 Identities = 42/185 (22%), Positives = 87/185 (47%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELD 197 +KL+ L ++ + + EL K N +E D LK A +I + R+EL+ Sbjct: 134 KKLERALEKQSETVDELTGKNNQILKEKDELKTQLYAA----------LQQIENLRKELN 183 Query: 198 NSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQE 377 + +RA +++H +E LR+ +S LE + + + D I + +L+ +++Q Sbjct: 184 DVLTKRALQEEELHSKEEKLRDIKSHQADLELEVKNSLDTIHRLESELKKQ----SKIQS 239 Query: 378 MDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDRTGEQD 557 Q + +A L E + + A + + +EMQ+ +I+ L +L ++ E++ Sbjct: 240 ----QMKVEKAHLEEEIAELKKSQAQDKAKLLEMQE----SIKDLSAIRADLANKLAEEE 291 Query: 558 VSQAA 572 ++ A Sbjct: 292 RAKKA 296 Score = 32.3 bits (72), Expect = 1.3 Identities = 21/91 (23%), Positives = 48/91 (52%), Gaps = 2/91 (2%) Frame = +3 Query: 165 NEIASFRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNIL--YKDEQ 338 +++ + REL+N E ++ Q L ++ ++Q H E+ E +H Q + L + ++ Sbjct: 36 SQVENLTRELENGEKQQLQMLDRLKEIQNHFDTCEA-----ERKHADLQISELTRHAEDA 90 Query: 339 LRDAHAWITRVQEMDILQSQSLQAELRERTD 431 + A +++ +Q QS++L+ E +R + Sbjct: 91 TKQAERYLSELQ-----QSEALKEEAEKRRE 116
>MYS2_DICDI (P08799) Myosin-2 heavy chain, non muscle (Myosin II heavy chain, non| muscle) Length = 2116 Score = 41.2 bits (95), Expect = 0.003 Identities = 28/111 (25%), Positives = 59/111 (53%), Gaps = 4/111 (3%) Frame = +3 Query: 27 KEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWAN-QDLLREQTNEIASFRRELDNS 203 ++++ E+E+ ILEL+ L D+ + D L+ + +N DL R+ E + + D+ Sbjct: 827 EKEIKEKEREILELKSNLTDSTTQKDKLEKSLKDTESNVLDLQRQLKAEKETLKAMYDSK 886 Query: 204 EAERAQHLK---QIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRD 347 +A AQ + ++ D++ L EK+ L+ Q R ++ + +E+L++ Sbjct: 887 DALEAQKRELEIRVEDMESELDEKKLALENLQNQKRSVEEKVRDLEEELQE 937 Score = 38.9 bits (89), Expect = 0.013 Identities = 37/150 (24%), Positives = 75/150 (50%), Gaps = 8/150 (5%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELD 197 +KL++ L + E +L+L+ +L E +TLK + + A + RE + ELD Sbjct: 852 DKLEKSLKDTESNVLDLQRQLK---AEKETLKAMYDSKDALEAQKRELEIRVEDMESELD 908 Query: 198 NSEA--ERAQHLKQ-----IHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHA 356 + E Q+ K+ + DL+E L+E++ LE+ + ++ L + +++ D + Sbjct: 909 EKKLALENLQNQKRSVEEKVRDLEEELQEEQKLRNTLEKLKKKYEEE-LEEMKRVNDGQS 967 Query: 357 -WITRVQEMDILQSQSLQAELRERTDQFGQ 443 I+R++++ LQ E+ E T+ F + Sbjct: 968 DTISRLEKI----KDELQKEVEELTESFSE 993
>MD1L1_MOUSE (Q9WTX8) Mitotic spindle assembly checkpoint protein MAD1 (Mitotic| arrest deficient-like protein 1) (MAD1-like 1) Length = 717 Score = 41.2 bits (95), Expect = 0.003 Identities = 46/188 (24%), Positives = 88/188 (46%), Gaps = 2/188 (1%) Frame = +3 Query: 33 QLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDNSEAE 212 QL ER + I + L RE +++ H+ A +L R + ++ RE+D ++ E Sbjct: 50 QLEERAEQIRS-KSYLIQVEREKMQMELSHKR--ARVELERAASTNARNYEREVDRNQ-E 105 Query: 213 RAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQEMDILQ 392 ++Q+ + + EK + L E+HR+ + N+ +QLR+ QE + Sbjct: 106 LLARIRQLQECEATAEEKMREQL---ERHRLCKQNLDAVSQQLRE--------QEDSLAS 154 Query: 393 SQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDRTGEQDVS--Q 566 ++ + + L+ R + Q A Q+ V+ + ++ QLEL + + + Q + Q Sbjct: 155 AREMISSLKGRVSEL-QLSAMDQKVQVKRLESEKQELKE-QLELQQRKWQEANQKIQELQ 212 Query: 567 AAQDGSAE 590 A+QD AE Sbjct: 213 ASQDERAE 220 Score = 35.4 bits (80), Expect = 0.15 Identities = 26/138 (18%), Positives = 69/138 (50%), Gaps = 2/138 (1%) Frame = +3 Query: 27 KEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDNSE 206 +E + + + EL++ D ++ L+ + Q + +L + + E +EL S+ Sbjct: 156 REMISSLKGRVSELQLSAMDQKVQVKRLESEKQELKEQLELQQRKWQEANQKIQELQASQ 215 Query: 207 AERAQHLKQIHDLQEH--LREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQEM 380 ERA+H ++I DL++ L+E+++ + + + + + ++L + + + ++E Sbjct: 216 DERAEHEQKIKDLEQKLCLQEQDAAVVKSMKSELMRMPRMERELKRLHEENTHLREMKET 275 Query: 381 DILQSQSLQAELRERTDQ 434 + L ++ L+ R+ + Q Sbjct: 276 NGLLTEELEGLQRKLSRQ 293
>MY18B_HUMAN (Q8IUG5) Myosin-18B (Myosin XVIIIb)| Length = 2567 Score = 40.8 bits (94), Expect = 0.004 Identities = 53/211 (25%), Positives = 89/211 (42%), Gaps = 33/211 (15%) Frame = +3 Query: 18 EKLKEQLHEREKYILE-------LEMKLNDTHRELDTLK-----IDHQAV---WANQDLL 152 EK+ QL + E E L L H EL+ + +D Q + DLL Sbjct: 1834 EKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLL 1893 Query: 153 R---EQTNEIASFRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNIL 323 + E +++ ++ + A+ A + QI +LQ L E + + L+EQ +VAQ I Sbjct: 1894 KRIDEDQDDLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQEQLQVAQMRIE 1953 Query: 324 YKDEQLRD------AHAWI------TRVQEMDILQSQSLQAELRERTDQFGQ---CWATF 458 Y ++ D A I T Q++ I + + L LR+ + G+ AT Sbjct: 1954 YLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEELSQAATS 2013 Query: 459 QQQYVEMQQGFLHTIQRLQLELIELRDRTGE 551 + Q E Q + ++ L+ ++ EL R E Sbjct: 2014 ESQQRESSQYYQRRLEELKADMEELVQREAE 2044
>MYSN_DROME (Q99323) Myosin heavy chain, non-muscle (Zipper protein) (Myosin II)| (Non-muscle MHC) Length = 2057 Score = 40.8 bits (94), Expect = 0.004 Identities = 41/179 (22%), Positives = 76/179 (42%), Gaps = 11/179 (6%) Frame = +3 Query: 18 EKLKEQLHEREKYILE---LEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRR 188 E+L+E+ R+K LE L+ K+ +L +Q + + LL E+ N+++ Sbjct: 1041 EQLEEEEAARQKLQLEKVQLDAKIKKYEEDLALTDDQNQKLLKEKKLLEERANDLSQTLA 1100 Query: 189 ELDNSEAERAQHLKQ--------IHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLR 344 E E E+A+HL + I +L+E L + + Q + R + + EQL Sbjct: 1101 E----EEEKAKHLAKLKAKHEATITELEERLHKDQQQRQESDRSKRKIETEVADLKEQLN 1156 Query: 345 DAHAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLE 521 + + +Q + + L L R D+ AT Q+ E++ + L+ E Sbjct: 1157 ERRVQVDEMQAQLAKREEELTQTLL-RIDEESATKATAQKAQRELESQLAEIQEDLEAE 1214 Score = 38.9 bits (89), Expect = 0.013 Identities = 40/190 (21%), Positives = 80/190 (42%), Gaps = 1/190 (0%) Frame = +3 Query: 15 AEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRREL 194 +E++ ++ E+ E E K+ RELD D + + N+ + + EL Sbjct: 1548 SEQIAQERDTAEREAREKETKVLSVSRELDEAF----------DKIEDLENKRKTLQNEL 1597 Query: 195 DNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNI-LYKDEQLRDAHAWITRV 371 D+ + K +H+L++ R ESQ L+ Q+ +D++ L +D +LR Sbjct: 1598 DDLANTQGTADKNVHELEKAKRALESQLAELKAQNEELEDDLQLTEDAKLR--------- 1648 Query: 372 QEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDRTGE 551 L+ ++ QF + ++ E ++G + ++ L+ EL E R + Sbjct: 1649 ----------LEVNMQALRSQFERDLLAKEEGAEEKRRGLVKQLRDLETELDEERKQRTA 1698 Query: 552 QDVSQAAQDG 581 S+ +G Sbjct: 1699 AVASKKKLEG 1708 Score = 35.4 bits (80), Expect = 0.15 Identities = 29/138 (21%), Positives = 62/138 (44%), Gaps = 4/138 (2%) Frame = +3 Query: 21 KLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDN 200 K +E+L ++E + ++ KL+ + + +Q + L EQ E + Sbjct: 933 KQEEKLVQKEDELKQVREKLDTLAKNTQEYERKYQQALVEKTTLAEQLQAEIELCAEAEE 992 Query: 201 SEAERAQHLKQIHDLQEHLR----EKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITR 368 S + +++ D+ + L E+E + LAL + + + NI +EQL + A + Sbjct: 993 SRSRLMARKQELEDMMQELETRIEEEEERVLALGGEKKKLELNIQDLEEQLEEEEAARQK 1052 Query: 369 VQEMDILQSQSLQAELRE 422 +Q L+ L A++++ Sbjct: 1053 LQ----LEKVQLDAKIKK 1066
>RB6I2_HUMAN (Q8IUD2) RAB6-interacting protein 2 (ERC protein 1)| Length = 1116 Score = 40.4 bits (93), Expect = 0.005 Identities = 33/120 (27%), Positives = 57/120 (47%), Gaps = 11/120 (9%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELD 197 E L+EQL ++EK + L+ ++ + DT D A+ ++ L E+ I + + D Sbjct: 581 ENLQEQLRDKEKQMSSLKERVKSL--QADTTNTD-TALTTLEEALAEKERTIERLKEQRD 637 Query: 198 NSEAERAQHL----KQIHDLQEH-------LREKESQYLALEEQHRVAQDNILYKDEQLR 344 E E+ + + K + DL+E L EKE+ L L+E + L KD +L+ Sbjct: 638 RDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLK 697 Score = 38.1 bits (87), Expect = 0.023 Identities = 47/182 (25%), Positives = 82/182 (45%), Gaps = 11/182 (6%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLK-IDHQAVWANQDLLRE---QTNEIASFR 185 E LKE L +E+ L+ +++ L+ + + ++ QD+ E Q EI + Sbjct: 504 EVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLK 563 Query: 186 RELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKD-------EQLR 344 LD E + K+I +LQE LR+KE Q +L+E+ + Q + D E L Sbjct: 564 DMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALA 623 Query: 345 DAHAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLEL 524 + I R++E Q + E +E D + + +++ V + QG L + L+L Sbjct: 624 EKERTIERLKE----QRDRDEREKQEEIDNYKKDLKDLKEK-VSLLQGDLSEKEASLLDL 678 Query: 525 IE 530 E Sbjct: 679 KE 680 Score = 32.3 bits (72), Expect = 1.3 Identities = 33/146 (22%), Positives = 71/146 (48%), Gaps = 7/146 (4%) Frame = +3 Query: 9 VAAEKLKEQLHEREK-YILE----LEMKLNDTHREL-DTLKIDHQAVWANQDLLREQTNE 170 VA K KEQ+ +++ +LE E LND+ ++L D+L+ + ++ LRE Sbjct: 793 VANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQI 852 Query: 171 IASFRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDA 350 A L E+ R KQ+ +L + + + + +++ + Q ++ K+ L + Sbjct: 853 TAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNL 912 Query: 351 HAWITR-VQEMDILQSQSLQAELRER 425 A + ++E+ ++ ++L A + E+ Sbjct: 913 RAERRKHLEEVLEMKQEALLAAISEK 938
>EEA1_HUMAN (Q15075) Early endosome antigen 1 (Endosome-associated protein| p162) (Zinc finger FYVE domain-containing protein 2) Length = 1411 Score = 40.4 bits (93), Expect = 0.005 Identities = 31/142 (21%), Positives = 65/142 (45%), Gaps = 1/142 (0%) Frame = +3 Query: 9 VAAEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRR 188 V+ + ++ LH+++ +L+ +L+ + L + ++ L+E+ +E+ + Sbjct: 330 VSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVET--- 386 Query: 189 ELDNSEAERAQHLK-QIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWIT 365 + QHLK + LQ+ EKE L L+ + +L + QL +AH Sbjct: 387 --------KYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHG--- 435 Query: 366 RVQEMDILQSQSLQAELRERTD 431 R++E L S+ L + ++ D Sbjct: 436 RLKEQRQLSSEKLMDKEQQVAD 457 Score = 36.2 bits (82), Expect = 0.087 Identities = 30/152 (19%), Positives = 68/152 (44%), Gaps = 8/152 (5%) Frame = +3 Query: 12 AAEKLKEQLHEREKYILELEMKLNDTHREL---DTLKIDHQAVWAN-----QDLLREQTN 167 + +L QL+E ++ + +L++++ L + K +A N Q+ L+++ Sbjct: 622 SVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQ 681 Query: 168 EIASFRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRD 347 E+ +LD A+ + L+ HL+E + +YL+LE++ + I + + Sbjct: 682 ELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLE 741 Query: 348 AHAWITRVQEMDILQSQSLQAELRERTDQFGQ 443 A + + D+ Q + L +L R + + Sbjct: 742 VKASKEQALQ-DLQQQRQLNTDLELRATELSK 772 Score = 33.5 bits (75), Expect = 0.56 Identities = 45/179 (25%), Positives = 82/179 (45%), Gaps = 18/179 (10%) Frame = +3 Query: 75 KLNDTHRELDTLKIDHQAVWAN-QDLLREQTNEIASFRRELDNSEAERAQHLKQIHDLQE 251 KL D ++L + +A + + L + E+A + +EL ++ + ++ L E Sbjct: 250 KLKDECKKLQSQYASSEATISQLRSELAKGPQEVAVYVQELQKLKSSVNELTQKNQTLTE 309 Query: 252 HLREKESQYLALEEQHR---VAQDNIL----YKD---EQLRD-AHAWITRVQEMDILQS- 395 +L +KE Y LEE+H V++ NI KD +QL+ A T + + + S Sbjct: 310 NLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVELSE 369 Query: 396 -----QSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDRTGEQD 557 Q L+ EL E ++ A F+Q + ++ H +Q LQ E+ +L + E + Sbjct: 370 KGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQ-LQSEINQLHSKLLETE 427 Score = 32.7 bits (73), Expect = 0.96 Identities = 43/186 (23%), Positives = 83/186 (44%), Gaps = 21/186 (11%) Frame = +3 Query: 30 EQLHEREKYILELEMKLN--------------DTHRELDTLKIDHQAVWANQD----LLR 155 E+L ++E+ + +L++KL+ + +LD K HQ A Q LR Sbjct: 446 EKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLR 505 Query: 156 EQTNEIASFRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDE 335 E N++ R++ + + ++ Q+L E L +K + ++L E+ R +++ K + Sbjct: 506 EAQNDLEQVLRQIGDKD-QKIQNL-------EALLQKSKENISLLEKER---EDLYAKIQ 554 Query: 336 QLRDAHAWITRVQEMD-ILQSQ--SLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQ 506 A + ++QE + LQ Q L +L+ +++ Q Q V+ Q+ L Q Sbjct: 555 AGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQ-VQEQKAHLRAAQ 613 Query: 507 RLQLEL 524 L L Sbjct: 614 DRVLSL 619 Score = 32.0 bits (71), Expect = 1.6 Identities = 35/201 (17%), Positives = 84/201 (41%), Gaps = 1/201 (0%) Frame = +3 Query: 33 QLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDNSEAE 212 +L E + + ++ ++ D +++ L+ Q N LL ++ ++ + + + A Sbjct: 503 KLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAV 562 Query: 213 RAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQEMDILQ 392 Q ++ H LQE + + + E H+ AQ+N+ +Q+++ A + Q+ + Sbjct: 563 LNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENL---HDQVQEQKAHLRAAQDRVL-- 617 Query: 393 SQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDRTGEQDVSQ-A 569 SL+ + E Q + Q ++++ + + + D D +Q A Sbjct: 618 --SLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNA 675 Query: 570 AQDGSAESSYVQSKGSSMACK 632 QD E + + ++ + K Sbjct: 676 LQDKQQELNKITTQLDQVTAK 696
>BPAEA_MOUSE (Q91ZU8) Bullous pemphigoid antigen 1, isoform 5 (BPA)| (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin) Length = 2611 Score = 40.4 bits (93), Expect = 0.005 Identities = 32/145 (22%), Positives = 65/145 (44%), Gaps = 7/145 (4%) Frame = +3 Query: 12 AAEKLKEQLHEREKYILE---LEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEI--- 173 A +L++Q E L+ E + REL+T+ + +A + +R+ T E Sbjct: 1139 AENELRKQQRNVEDIALQKLRAESEAKQYRRELETIVREKEAAERELERVRQLTAEAEAR 1198 Query: 174 -ASFRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDA 350 A+ L N ++ ++ L++HLR K+S LE+Q R + + K + + Sbjct: 1199 RAAVEENLRNFRSQLQENTFTRQTLEDHLRRKDSSLSDLEQQKRALVEELQRKRDHEEEL 1258 Query: 351 HAWITRVQEMDILQSQSLQAELRER 425 + +++ Q Q + +L+E+ Sbjct: 1259 LRLVKQMERDLAFQKQVAEKQLKEK 1283 Score = 32.3 bits (72), Expect = 1.3 Identities = 29/165 (17%), Positives = 75/165 (45%), Gaps = 6/165 (3%) Frame = +3 Query: 9 VAAEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRR 188 + A+ K+QL +++ + D HR++ +L +D L + N ++ F++ Sbjct: 1578 IQADGFKDQLRNTNEHLHKQTKTEQDFHRKIKSL----------EDDLAQSQNLVSEFKQ 1627 Query: 189 ELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITR 368 + D Q I ++ +R ++ A +E+ R + + Q+++ + + R Sbjct: 1628 KCD-------QQSMIIQKTEKEVRSLSAELSASKEEKRREEQKAQLQRAQVQELNDRLKR 1680 Query: 369 VQE---MDILQSQSLQAE---LRERTDQFGQCWATFQQQYVEMQQ 485 VQ+ + ++ Q + L+E +D+F + F+++ ++ + Sbjct: 1681 VQDELHLKTIEEQMTHRKMILLQEESDKFKRSADEFRKKMEKLME 1725
>PAM_STRPY (P49054) Plasminogen-binding group A steptococcal M-like protein| PAM precursor (Fragment) Length = 388 Score = 40.4 bits (93), Expect = 0.005 Identities = 38/134 (28%), Positives = 62/134 (46%), Gaps = 18/134 (13%) Frame = +3 Query: 3 HVVAAEKLKEQLHEREKYILE---LEMKLNDTHRELDTLKIDHQAVWANQDLLR------ 155 ++V AE Q+ E ++ LE L+ L + EL LK D + + A+ +L R Sbjct: 43 NLVRAELWYRQIQENDQLKLENKGLKTDLREKEEELQGLKDDVEKLTADAELQRLKNERH 102 Query: 156 --EQTNEIASFRRELDNSEAERAQHLKQIHDLQEHL-------REKESQYLALEEQHRVA 308 + + S R + D EAER ++ D QEHL EKE+ E + + A Sbjct: 103 EEAELERLKSERHDHDKKEAERKALEDKLADKQEHLNGALRYINEKEA-----EAKEKEA 157 Query: 309 QDNILYKDEQLRDA 350 + L +++Q+ DA Sbjct: 158 EQKKLKEEKQISDA 171
>MUKB_MANSM (Q65TL9) Chromosome partition protein mukB (Structural maintenance of| chromosome-related protein) Length = 1499 Score = 40.4 bits (93), Expect = 0.005 Identities = 49/212 (23%), Positives = 86/212 (40%), Gaps = 44/212 (20%) Frame = +3 Query: 48 EKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQ-------------------TNE 170 E+ + E+ + N+ +REL L D Q + D +EQ +++ Sbjct: 865 EQQMREINQQRNEINRELTALSTDEQQLRIKLDNAKEQMQLLNKLIPQLNVIADESLSDK 924 Query: 171 IASFRRELDNSEAER---AQH---LKQIH--------DLQEHLREKESQYLALEEQHRVA 308 + R +LD +E + QH L Q+ D + + R K+ Y A++ Q + Sbjct: 925 VEECREQLDIAEQDEIFIRQHGMTLSQLEPIANTLQSDPENYERLKDDLYQAIDMQKQAQ 984 Query: 309 QDNILYKDEQLRDAH-----AWITRVQEMD------ILQSQSLQAELRERTDQFGQCWAT 455 Q D R AH T +++ + Q Q+ + + R++ Q Q +A Sbjct: 985 QKAFALADVIHRQAHFSYEDTVKTETNDLNEKLRVRLEQVQAKREQQRDQVRQKQQQFAQ 1044 Query: 456 FQQQYVEMQQGFLHTIQRLQLELIELRDRTGE 551 + Q Y+++Q F Q L+ EL D GE Sbjct: 1045 YNQVYIQLQSSFETKNQMLK----ELMDEVGE 1072 Score = 30.4 bits (67), Expect = 4.8 Identities = 47/201 (23%), Positives = 75/201 (37%), Gaps = 37/201 (18%) Frame = +3 Query: 24 LKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIAS-------- 179 L E L R+ + ++E L + L+ +K+ + L+ E TN +AS Sbjct: 251 LPENLGVRKAF-QDMESALRENRMTLEAIKMTQSDRDLFKHLITETTNYVASDYMRNANE 309 Query: 180 ----------FRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQD----- 314 FR+E +++E+ ++ DL E ALE H+ A D Sbjct: 310 RQGNIETALSFRKEWYAAKSEQDLSQHRLIDLSREAAELTENEKALEIDHQSASDHLNLV 369 Query: 315 -NILYKDEQL----RDAHAWITRVQEMDI--------LQSQSLQAE-LRERTDQFGQCWA 452 N L E++ D + +++E I L+ LQ E L DQ A Sbjct: 370 LNALRHQERIERYQEDVNELTEKLEEQKIVVENANEQLEESQLQFETLETEVDQIRGQLA 429 Query: 453 TFQQQYVEMQQGFLHTIQRLQ 515 +QQ Q L Q +Q Sbjct: 430 DYQQALDAQQTRALQYQQAIQ 450
>RB6I2_RAT (Q811U3) RAB6-interacting protein 2 (ERC protein 1) (ERC1)| (CAZ-associated structural protein 2) (CAST2) Length = 948 Score = 40.4 bits (93), Expect = 0.005 Identities = 37/148 (25%), Positives = 69/148 (46%), Gaps = 11/148 (7%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELD 197 E L+EQL ++EK + L+ ++ + DT D A+ ++ L ++ I + + D Sbjct: 553 ENLQEQLRDKEKQMSSLKERVKSL--QADTTNTD-TALTTLEEALADKERTIERLKEQRD 609 Query: 198 NSEAERAQHL----KQIHDLQEH-------LREKESQYLALEEQHRVAQDNILYKDEQLR 344 E E+ + + K + DL+E L EKE+ L L+E + L KD +L+ Sbjct: 610 RDEREKQEEIDTYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLK 669 Query: 345 DAHAWITRVQEMDILQSQSLQAELRERT 428 + + +E + L+ +S + E T Sbjct: 670 TLEIALEQKKE-ECLKMESQLKKAHEAT 696 Score = 39.3 bits (90), Expect = 0.010 Identities = 48/182 (26%), Positives = 82/182 (45%), Gaps = 11/182 (6%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLK-IDHQAVWANQDLLRE---QTNEIASFR 185 E LKE L +E+ L+ +++ L+ + + ++ QD+ E Q EI + Sbjct: 476 EVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLK 535 Query: 186 RELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKD-------EQLR 344 LD E + K+I +LQE LR+KE Q +L+E+ + Q + D E L Sbjct: 536 DMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALA 595 Query: 345 DAHAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLEL 524 D I R++E Q + E +E D + + +++ V + QG L + L+L Sbjct: 596 DKERTIERLKE----QRDRDEREKQEEIDTYKKDLKDLKEK-VSLLQGDLSEKEASLLDL 650 Query: 525 IE 530 E Sbjct: 651 KE 652
>SAS6_CAEBR (Q60P76) Spindle assembly abnormal protein 6| Length = 497 Score = 40.4 bits (93), Expect = 0.005 Identities = 40/197 (20%), Positives = 91/197 (46%), Gaps = 18/197 (9%) Frame = +3 Query: 6 VVAAEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWA----NQDLLREQTNEI 173 V EK + + + EK I E E ++ + EL+ +K + + + +DL+ E N++ Sbjct: 206 VAEMEKRNQSIEDLEKKIEEQEERIREMEDELELVKEERENIRVIAEEKEDLVAELQNDL 265 Query: 174 ASFRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAH 353 S REL+ ++ E K + + Q + + + + +A +++ I R+ Sbjct: 266 ESVNRELEENQEELEIVGKMLGEEQGKVDQLQKRNVAHQKELATRFRKIGNCRNNFRNFF 325 Query: 354 AWITR-------VQEMDILQSQSLQAELRER-------TDQFGQCWATFQQQYVEMQQGF 491 ++ + Q +DI + + L+A+L+E+ T G + + V+MQ+ Sbjct: 326 NFLLKRSSVEQSQQSLDIRKLRELEADLKEKDSMVENLTQTVGILKKELEDERVKMQE-T 384 Query: 492 LHTIQRLQLELIELRDR 542 + + + L++E +++R Sbjct: 385 MTSFESLKVENESVKER 401
>EZRI_RABIT (Q8HZQ5) Ezrin (p81) (Cytovillin) (Villin-2)| Length = 585 Score = 40.0 bits (92), Expect = 0.006 Identities = 30/109 (27%), Positives = 59/109 (54%), Gaps = 1/109 (0%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDH-QAVWANQDLLREQTNEIASFRREL 194 +K +++L ++ + L+LE + E + L+ D A+ A ++L R+ ++I S Sbjct: 358 KKAEKELSDQIQRALQLEDERKRAQEESERLEADRVAALRAKEELERQAADQIKS----Q 413 Query: 195 DNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQL 341 + AE A++ +I L+E R KES+ + + R AQD+++ E+L Sbjct: 414 EQLAAELAEYTAKIALLEEARRRKESEVEEWQHRAREAQDDLVKTKEEL 462
>SMC_METJA (Q59037) Chromosome partition protein smc homolog| Length = 1169 Score = 40.0 bits (92), Expect = 0.006 Identities = 34/135 (25%), Positives = 64/135 (47%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELD 197 EK E++ E K I ELE+++ + + LD+ NE+ E++ Sbjct: 289 EKGNEEVLELHKSIKELEVEIENDKKVLDS-----------------SINELKKVEVEIE 331 Query: 198 NSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQE 377 N + E + K+I + ++ + EKE Q +EE+ + N+ Y+ E+L++A Sbjct: 332 NKKKEIKETQKKIIENRDSIIEKEQQIKEIEEKIK----NLNYEKERLKEA--------- 378 Query: 378 MDILQSQSLQAELRE 422 I +S+S+ L+E Sbjct: 379 --IAESESIIKHLKE 391 Score = 35.4 bits (80), Expect = 0.15 Identities = 41/212 (19%), Positives = 101/212 (47%), Gaps = 21/212 (9%) Frame = +3 Query: 18 EKLKEQLHEREKY-ILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRREL 194 E K ++ E+ I ELE+K D EL+ L + + + + + + NE+ R ++ Sbjct: 727 EMRKREIAEKNTIKIKELELKNKDILEELEELNLKREEILNRINEIESKINELIERREKI 786 Query: 195 DN--SEAERAQHLKQIHDLQEHLR--EKESQYL--ALEEQHRVAQDNILYKDEQLRDAHA 356 N E E ++LK++++++ L+ EKE L +++ + ++ ++ K E+L + Sbjct: 787 INELKEYESDENLKRMNEIEGELKILEKEKAKLKNEIDKGLTLVKEILIPKIEELNKKVS 846 Query: 357 WITRVQ----------EMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQ 506 + + + I ++ S+ E R+R ++ + ++ ++++ + T++ Sbjct: 847 ELINKKVILEKNISFYKESIEKNLSILEEKRKRYEELAKNLKELTEKKEQLEKE-IETLE 905 Query: 507 RLQLELI----ELRDRTGEQDVSQAAQDGSAE 590 R + E++ ++ +R E V +A + E Sbjct: 906 RERREILRKVRDIENRINELMVEKAKYESKLE 937
>TRHY_RABIT (P37709) Trichohyalin| Length = 1407 Score = 40.0 bits (92), Expect = 0.006 Identities = 46/184 (25%), Positives = 82/184 (44%), Gaps = 4/184 (2%) Frame = +3 Query: 27 KEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDNSE 206 +EQ +RE++ + D + L +++ + A ++ LR + R+ + Sbjct: 150 EEQRKKRERFEQHYSRQYRDKEQRLQRQELEERR--AEEEQLRRRKG------RDAEEFI 201 Query: 207 AERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQEMDI 386 E ++ +L+ LRE+E Q EQH A + ++EQL W +E Sbjct: 202 EEEQLRRREQQELKRELREEEQQRRERREQHERA---LQEEEEQLLRQRRWREEPREQQQ 258 Query: 387 LQSQSLQAELRERTDQFGQCWATFQQ----QYVEMQQGFLHTIQRLQLELIELRDRTGEQ 554 L+ + E+RER + Q QQ Q +E ++ Q+L+ EL E+R+R EQ Sbjct: 259 LRRE--LEEIREREQRLEQEERREQQLRREQRLEQEE---RREQQLRRELEEIRER--EQ 311 Query: 555 DVSQ 566 + Q Sbjct: 312 RLEQ 315 Score = 36.6 bits (83), Expect = 0.066 Identities = 35/136 (25%), Positives = 61/136 (44%), Gaps = 2/136 (1%) Frame = +3 Query: 141 QDLLREQTNEIASFRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEE--QHRVAQD 314 Q+ LRE+ RR+ E + L++ D + +E+E QY LEE Q +D Sbjct: 544 QEQLREEEELQREKRRQEREREYREEEKLQREEDEKRRRQERERQYRELEELRQEEQLRD 603 Query: 315 NILYKDEQLRDAHAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFL 494 L ++EQL + +E + L+ Q + +LRE Q +Q+ + Sbjct: 604 RKLREEEQL-------LQEREEERLRRQERERKLREEEQLLRQEEQELRQERERKLREEE 656 Query: 495 HTIQRLQLELIELRDR 542 ++R + EL + R+R Sbjct: 657 QLLRREEQELRQERER 672 Score = 34.7 bits (78), Expect = 0.25 Identities = 44/195 (22%), Positives = 79/195 (40%), Gaps = 8/195 (4%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQ--TNEIASFRRE 191 E+ EQ RE+ + + E + REL+ ++ Q + Q+ REQ E+ RE Sbjct: 310 EQRLEQEERREQRLEQEERREQQLKRELEEIREREQRL--EQEERREQLLAEEVREQARE 367 Query: 192 LDNSEAERAQHLKQIH------DLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAH 353 S R Q + + R +E Q L +++ R Q+ +EQ R Sbjct: 368 RGESLTRRWQRQLESEAGARQSKVYSRPRRQEEQSLRQDQERRQRQERERELEEQARRQQ 427 Query: 354 AWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIEL 533 W + Q S + LRER + + Q+ E +Q +R +L+ +E Sbjct: 428 QWQAEEESERRRQRLSARPSLRERQLRAEERQEQEQRFREEEEQ---RRERRQELQFLEE 484 Query: 534 RDRTGEQDVSQAAQD 578 ++ ++ +Q Q+ Sbjct: 485 EEQLQRRERAQQLQE 499 Score = 33.9 bits (76), Expect = 0.43 Identities = 37/144 (25%), Positives = 61/144 (42%), Gaps = 4/144 (2%) Frame = +3 Query: 15 AEKLKEQ---LHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFR 185 A KL+E+ L ERE+ L + + E L+ + Q +L +E+ + Sbjct: 955 ARKLREEEQLLQEREEERLRRQERARKLREEEQLLRREEQ------ELRQERDRKFREEE 1008 Query: 186 RELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLR-DAHAWI 362 + L E ER + ++ +E R+ Q LEEQ R +D +EQ+R + Sbjct: 1009 QLLQEREEERLRRQERDRKFREEERQLRRQ--ELEEQFRQERDRKFRLEEQIRQEKEEKQ 1066 Query: 363 TRVQEMDILQSQSLQAELRERTDQ 434 R QE D + Q R+ +Q Sbjct: 1067 LRRQERDRKFREEEQQRRRQEREQ 1090 Score = 33.9 bits (76), Expect = 0.43 Identities = 35/137 (25%), Positives = 61/137 (44%), Gaps = 3/137 (2%) Frame = +3 Query: 21 KLKEQ---LHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRE 191 KL+E+ L ERE+ L + + E L+ + Q + Q+ R+ E RRE Sbjct: 673 KLREEEQLLQEREEERLRRQERARKLREEEQLLRQEEQEL--RQERERKLREEEQLLRRE 730 Query: 192 LDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRV 371 ER + L++ L + E+ + E+Q R +D ++EQL + Sbjct: 731 EQLLRQERDRKLREEEQLLQESEEERLRRQEREQQLRRERDRKFREEEQL-------LQE 783 Query: 372 QEMDILQSQSLQAELRE 422 +E + L+ Q + +LRE Sbjct: 784 REEERLRRQERERKLRE 800 Score = 32.3 bits (72), Expect = 1.3 Identities = 37/158 (23%), Positives = 70/158 (44%), Gaps = 8/158 (5%) Frame = +3 Query: 33 QLHEREKYILELEMKLNDTH-----RELDTLKIDHQAVWANQDLLREQTNEIASFRRELD 197 +L E E+ + + E +L E L+ + Q+ R+ E RRE Sbjct: 889 KLREEEQLLRQEEQELRQERDRKLREEEQLLQESEEERLRRQERERKLREEEQLLRREEQ 948 Query: 198 NSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRV--AQDNILYKDEQ-LRDAHAWITR 368 ERA+ L++ L L+E+E + L +E+ R ++ +L ++EQ LR R Sbjct: 949 ELRRERARKLREEEQL---LQEREEERLRRQERARKLREEEQLLRREEQELRQERDRKFR 1005 Query: 369 VQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQ 482 +E + + + + +ER +F + ++Q +E Q Sbjct: 1006 EEEQLLQEREEERLRRQERDRKFREEERQLRRQELEEQ 1043 Score = 30.0 bits (66), Expect = 6.2 Identities = 45/192 (23%), Positives = 80/192 (41%), Gaps = 1/192 (0%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQD-LLREQTNEIASFRREL 194 E K + ERE+ ELE + L+ + Q + ++ LR Q E RE Sbjct: 576 EDEKRRRQERERQYRELEELRQEEQLRDRKLREEEQLLQEREEERLRRQERERKL--REE 633 Query: 195 DNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQ 374 + + Q L+Q + + LRE+E E++ R ++ L ++EQL + + Sbjct: 634 EQLLRQEEQELRQ--ERERKLREEEQLLRREEQELRQERERKLREEEQL-------LQER 684 Query: 375 EMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDRTGEQ 554 E + L+ Q +LRE Q +Q+ + ++R + L + RDR + Sbjct: 685 EEERLRRQERARKLREEEQLLRQEEQELRQERERKLREEEQLLRREEQLLRQERDRKLRE 744 Query: 555 DVSQAAQDGSAE 590 + Q Q+ E Sbjct: 745 E-EQLLQESEEE 755
>RIMB1_RAT (Q9JIR0) Peripheral-type benzodiazepine receptor-associated protein| 1 (PRAX-1) (RIM-binding protein 1) (RIM-BP1) Length = 1847 Score = 40.0 bits (92), Expect = 0.006 Identities = 46/178 (25%), Positives = 80/178 (44%), Gaps = 18/178 (10%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTN-EIASFRREL 194 E L+++ ++++ ELE++L E L ++ + + + +EQ E A + +L Sbjct: 349 ESLEQEARKKQRRCEELELQLRAAQNENARL-VEENSRLSGKATEKEQVEWENAELKGQL 407 Query: 195 DNSEAERAQHLKQIHDLQ----------EHLREKESQYLALEEQHRVAQDNILYKDEQLR 344 ER L++ LQ EH+R+ + LEE+H A+ ++ K E++R Sbjct: 408 LGVTQERDSALRKSQGLQSKLESLEQVLEHMRKVAQRRQQLEEEHEQARLSLQEKQEEVR 467 Query: 345 ---DAHAWITRVQE--MDILQS--QSLQAELRERTDQFGQCWATFQQQYVEMQQGFLH 497 A A R E + +L+S S+QA +RE Q F E+Q LH Sbjct: 468 RLQQAQAEAKREHEGAVQLLESTLDSMQARVRELEGQCRSQTERFSLLAQELQAFRLH 525
>KIF4A_CHICK (Q90640) Chromosome-associated kinesin KIF4A (Chromokinesin)| Length = 1225 Score = 40.0 bits (92), Expect = 0.006 Identities = 37/147 (25%), Positives = 67/147 (45%), Gaps = 5/147 (3%) Frame = +3 Query: 15 AEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRREL 194 +E+ +++L E E I EL+ KLN+ + L + + V +RE N+ R++ Sbjct: 601 SERRRKRLQELEGQINELKKKLNEQAKLLKLKESTERTVSKLNQEIREMKNQRVQLMRQM 660 Query: 195 DNSEAERAQHLKQIHD-----LQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAW 359 +AE+ + KQ D L+E R+++ + L LE + + K E+ A+ Sbjct: 661 -KEDAEKFRQWKQQKDKEVIQLKERDRKRQYELLKLERDFQKQASVLRRKTEEAAAANKR 719 Query: 360 ITRVQEMDILQSQSLQAELRERTDQFG 440 + D LQ Q A+ R+ + G Sbjct: 720 L-----KDALQKQREAADKRKESQNRG 741
>CCD46_MOUSE (Q5PR68) Coiled coil domain containing protein 46| Length = 954 Score = 39.7 bits (91), Expect = 0.008 Identities = 43/202 (21%), Positives = 88/202 (43%), Gaps = 6/202 (2%) Frame = +3 Query: 3 HVVAAEKLKEQLHEREKYILELEMKLNDTH--RELDTLKIDHQAVWANQDLLREQTNEIA 176 H ++ K + E E+ I +L+ ++ ++ R+ +++ L ++ Sbjct: 494 HALSTSKTSGVIEELEQNICQLKQQVQESELQRKQQVKDQENKFHMEKNHLKHTYEKKVH 553 Query: 177 SFRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHA 356 + ELD E E AQ ++IH +E L+EKE Q + E R+ Q + A A Sbjct: 554 ELQSELDK-EKEDAQ--RKIHKFEEALKEKEEQLSRVTEVQRL----------QAQQADA 600 Query: 357 WITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTI----QRLQLEL 524 + + + S+ + E++E+ ++ + + + FL + QR + ++ Sbjct: 601 ALEEFKRQVEVNSEKVYGEMKEQMEKVEADLTRSKSLREKQSKEFLWQLEDAKQRYEQQI 660 Query: 525 IELRDRTGEQDVSQAAQDGSAE 590 +EL+ EQ+ + Q SAE Sbjct: 661 VELK-LEHEQEKTHLLQQHSAE 681
>M4K4_HUMAN (O95819) Mitogen-activated protein kinase kinase kinase kinase 4| (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase) Length = 1239 Score = 39.7 bits (91), Expect = 0.008 Identities = 39/161 (24%), Positives = 77/161 (47%), Gaps = 1/161 (0%) Frame = +3 Query: 27 KEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDNSE 206 ++QL E+E+Y +L L + + ++ K + L EQ RR+ + + Sbjct: 378 EQQLREQEEYKRQL---LAERQKRIEQQKEQRRR-------LEEQQRREREARRQQEREQ 427 Query: 207 AERAQHLK-QIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQEMD 383 R Q K ++ +L+ +E+E + A EE+ RV ++ Y QL + + V + Sbjct: 428 RRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQ-EYIRRQLEEEQRHL-EVLQQQ 485 Query: 384 ILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQ 506 +LQ Q++ E R R + + Q+Q ++ +Q +L ++Q Sbjct: 486 LLQEQAMLLECRWREMEEHRQAERLQRQ-LQQEQAYLLSLQ 525
>LRC45_CHICK (Q5ZI11) Leucine-rich repeat-containing protein 45| Length = 670 Score = 39.7 bits (91), Expect = 0.008 Identities = 37/179 (20%), Positives = 79/179 (44%), Gaps = 1/179 (0%) Frame = +3 Query: 9 VAAEKLKEQLHEREKYILELEMKLNDTHRELDTL-KIDHQAVWANQDLLREQTNEIASFR 185 V ++++ E+ K L+L ++ E+ +I V Q+ L EQ + + S + Sbjct: 243 VLSKEILNLKDEKTKQFLDLMDTIDKQREEIARSGRISAGRVSQLQEALNEQHSIMNSLK 302 Query: 186 RELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWIT 365 +L +EA A +++H+L E L + + ++ E+H + + ++ D + Sbjct: 303 AKLQMTEAALALSEQKVHNLGELLSATKQEQASMAERHFA---ELQQQKQEGADREGKLF 359 Query: 366 RVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDR 542 R D+ S LR + D+ + Q Q +++Q +T L+L ++ +R Sbjct: 360 R----DLSASNEKNLFLRNQVDELEKKCKVQQDQIFQLKQDLTNTTAELKLRAVQAEER 414
>FLIP1_HUMAN (Q7Z7B0) Filamin-A-interacting protein 1 (FILIP)| Length = 1213 Score = 39.7 bits (91), Expect = 0.008 Identities = 43/165 (26%), Positives = 76/165 (46%), Gaps = 29/165 (17%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTL--KIDHQAVWANQ-----DLLREQTNEIA 176 EKL E+ + K E+E K+ + RE D L K+ + +++ DLL+++ + I Sbjct: 545 EKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIE 604 Query: 177 SFRREL---------------DNS------EAER-AQHLKQIHDLQEHLREKESQYLALE 290 RE+ DN E ER + L+Q+ ++ L + E +Y LE Sbjct: 605 EVEREITRGRSRKGSELTCPEDNKIKELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLE 664 Query: 291 EQHRVAQDNILYKDEQLRDAHAWITRVQEMDILQSQSLQAELRER 425 ++ R QD + +QL + I + + ++ + S +AELR R Sbjct: 665 QKFRTEQDKANFLSQQLEEIKHQIAKNKAIEKGEVVSQEAELRHR 709 Score = 30.4 bits (67), Expect = 4.8 Identities = 33/156 (21%), Positives = 69/156 (44%), Gaps = 22/156 (14%) Frame = +3 Query: 30 EQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDNSEA 209 E+L E K + + E +L + ++ + + ++ A + LR++ E+ E+ +E+ Sbjct: 343 EELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKTES 402 Query: 210 ----------ERAQHLKQIHDLQEHLREKESQYLALEEQH------------RVAQDNIL 323 E H K++ E L+++ S+ LEE + ++ L Sbjct: 403 QCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNL 462 Query: 324 YKDEQLRDAHAWITRVQEMDILQSQSLQAELRERTD 431 KD L + +RV+E++ +S+ +AEL + D Sbjct: 463 TKD-LLNELEVVKSRVKELECSESRLEKAELSLKDD 497
>RB6I2_MOUSE (Q99MI1) RAB6-interacting protein 2 (ERC protein 1) (ERC1)| (CAZ-associated structural protein 2) (CAST2) Length = 1120 Score = 39.7 bits (91), Expect = 0.008 Identities = 36/148 (24%), Positives = 69/148 (46%), Gaps = 11/148 (7%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELD 197 E L+EQL ++EK + L+ ++ + DT D A+ ++ L ++ I + + D Sbjct: 581 ENLQEQLRDKEKQMSSLKERVKSL--QADTTNTD-TALTTLEEALADKERTIERLKEQRD 637 Query: 198 NSEAERAQHL----KQIHDLQEH-------LREKESQYLALEEQHRVAQDNILYKDEQLR 344 E E+ + + K + DL+E L EKE+ L ++E + L KD +L+ Sbjct: 638 RDEREKQEEIDTYKKDLKDLREKVSLLQGDLSEKEASLLDIKEHASSLASSGLKKDSRLK 697 Query: 345 DAHAWITRVQEMDILQSQSLQAELRERT 428 + + +E + L+ +S + E T Sbjct: 698 TLEIALEQKKE-ECLKMESQLKKAHEAT 724 Score = 38.5 bits (88), Expect = 0.017 Identities = 39/144 (27%), Positives = 65/144 (45%), Gaps = 11/144 (7%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLK-IDHQAVWANQDLLRE---QTNEIASFR 185 E LKE L +E+ L+ +++ L+ + + ++ QD+ E Q EI + Sbjct: 504 EVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLK 563 Query: 186 RELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKD-------EQLR 344 LD E + K+I +LQE LR+KE Q +L+E+ + Q + D E L Sbjct: 564 DMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALA 623 Query: 345 DAHAWITRVQEMDILQSQSLQAEL 416 D I R++E + Q E+ Sbjct: 624 DKERTIERLKEQRDRDEREKQEEI 647 Score = 30.4 bits (67), Expect = 4.8 Identities = 32/146 (21%), Positives = 71/146 (48%), Gaps = 7/146 (4%) Frame = +3 Query: 9 VAAEKLKEQLHEREK-YILE----LEMKLNDTHREL-DTLKIDHQAVWANQDLLREQTNE 170 VA K KEQ+ +++ +LE E L+D+ ++L D+L+ + ++ LRE Sbjct: 797 VANLKHKEQVEKKKSAQMLEEARRREDSLSDSSQQLQDSLRKKDDRIEELEEALRESVQI 856 Query: 171 IASFRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDA 350 A L E+ R KQ+ +L + + + + +++ + Q ++ K+ L + Sbjct: 857 TAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNL 916 Query: 351 HAWITR-VQEMDILQSQSLQAELRER 425 A + ++E+ ++ ++L A + E+ Sbjct: 917 RAERRKHLEEVLEMKQEALLAAISEK 942
>MD1L1_HUMAN (Q9Y6D9) Mitotic spindle assembly checkpoint protein MAD1 (Mitotic| arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181) Length = 718 Score = 39.7 bits (91), Expect = 0.008 Identities = 31/133 (23%), Positives = 64/133 (48%), Gaps = 2/133 (1%) Frame = +3 Query: 30 EQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDNSEA 209 E ++ + I EL+ + D + L+ + Q + DL ++ E +EL S+ Sbjct: 157 ETINALKGRISELQWSVMDQEMRVKRLESEKQELQEQLDLQHKKCQEANQKIQELQASQE 216 Query: 210 ERAQHLKQIHDLQE--HLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQEMD 383 RA H +QI DL++ L+E+++ + + V + + +QLR+ A + ++E + Sbjct: 217 ARADHEQQIKDLEQKLSLQEQDAAIVKNMKSELVRLPRLERELKQLREESAHLREMRETN 276 Query: 384 ILQSQSLQAELRE 422 L + L+ R+ Sbjct: 277 GLLQEELEGLQRK 289 Score = 34.7 bits (78), Expect = 0.25 Identities = 35/153 (22%), Positives = 66/153 (43%), Gaps = 20/153 (13%) Frame = +3 Query: 33 QLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDNSEAE 212 QL ER + I + L RE +++ H+ A +L R + ++ RE+D ++ E Sbjct: 50 QLEERAEQIRS-KSHLIQVEREKMQMELSHKR--ARVELERAASTSARNYEREVDRNQ-E 105 Query: 213 RAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAH------------- 353 ++Q+ + + EK + L E++R Q N+ ++LR+ Sbjct: 106 LLTRIRQLQEREAGAEEKMQEQL---ERNRQCQQNLDAASKRLREKEDSLAQAGETINAL 162 Query: 354 -------AWITRVQEMDILQSQSLQAELRERTD 431 W QEM + + +S + EL+E+ D Sbjct: 163 KGRISELQWSVMDQEMRVKRLESEKQELQEQLD 195
>KIF3A_PONPY (Q5R4H3) Kinesin-like protein KIF3A (Microtubule plus end-directed| kinesin motor 3A) Length = 702 Score = 39.7 bits (91), Expect = 0.008 Identities = 40/189 (21%), Positives = 78/189 (41%), Gaps = 1/189 (0%) Frame = +3 Query: 21 KLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDN 200 K + +L +REK +L+ + + +L L + + + DLL + + + L+ Sbjct: 449 KARAELEKREKDLLKAQQEHQSLLEKLSAL--EKKVIVGGVDLLAKAEEQ----EKLLEE 502 Query: 201 SEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQ-E 377 S E + K+ L+ L EKE + L +EE++ Q+ K ++L+ + + E Sbjct: 503 SNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSE 562 Query: 378 MDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDRTGEQD 557 M LQ Q Q E+ + Q + Q + + Q + + + GE Sbjct: 563 MADLQ-QEHQGEIEGLLENIRQLSRELRLQMLIIDNFIPRDYQEMIENYVHWNEDIGEWQ 621 Query: 558 VSQAAQDGS 584 + A G+ Sbjct: 622 LKCVAYTGN 630
>KIF3A_MACFA (Q4R628) Kinesin-like protein KIF3A (Microtubule plus end-directed| kinesin motor 3A) Length = 702 Score = 39.7 bits (91), Expect = 0.008 Identities = 38/168 (22%), Positives = 74/168 (44%) Frame = +3 Query: 21 KLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDN 200 K + +L +REK +L+ + + +L L + + + DLL + + + L+ Sbjct: 449 KARAELEKREKDLLKAQQEHQSLLEKLSAL--EKKVIVGGVDLLAKAEEQ----EKLLEE 502 Query: 201 SEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQEM 380 S E + K+ L+ L EKE + L +EE++ Q+ K ++L+ W Sbjct: 503 SNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQEEAQGKTKKLK--KVWTM----- 555 Query: 381 DILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLEL 524 ++ ++S A+L QQ++ +G L I++L EL Sbjct: 556 -LMAAKSEMADL--------------QQEHQREIEGLLENIRQLSREL 588 Score = 30.8 bits (68), Expect = 3.6 Identities = 28/108 (25%), Positives = 51/108 (47%) Frame = +3 Query: 15 AEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRREL 194 AE+L+ +L E+E+ L++E K E + VW +L +E+A ++E Sbjct: 514 AEQLRRELEEKEQERLDIEEKYTSLQEEAQGKTKKLKKVWT---MLMAAKSEMADLQQE- 569 Query: 195 DNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQ 338 H ++I L E++R+ S+ L L+ + DN + +D Q Sbjct: 570 ---------HQREIEGLLENIRQL-SRELRLQ---MLIIDNFIPRDYQ 604
>KIF3A_HUMAN (Q9Y496) Kinesin-like protein KIF3A (Microtubule plus end-directed| kinesin motor 3A) Length = 702 Score = 39.7 bits (91), Expect = 0.008 Identities = 38/168 (22%), Positives = 74/168 (44%) Frame = +3 Query: 21 KLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDN 200 K + +L +REK +L+ + + +L L + + + DLL + + + L+ Sbjct: 449 KARAELEKREKDLLKAQQEHQSLLEKLSAL--EKKVIVGGVDLLAKAEEQ----EKLLEE 502 Query: 201 SEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQEM 380 S E + K+ L+ L EKE + L +EE++ Q+ K ++L+ W Sbjct: 503 SNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQEEAQGKTKKLK--KVWTM----- 555 Query: 381 DILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLEL 524 ++ ++S A+L QQ++ +G L I++L EL Sbjct: 556 -LMAAKSEMADL--------------QQEHQREIEGLLENIRQLSREL 588 Score = 30.8 bits (68), Expect = 3.6 Identities = 28/108 (25%), Positives = 51/108 (47%) Frame = +3 Query: 15 AEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRREL 194 AE+L+ +L E+E+ L++E K E + VW +L +E+A ++E Sbjct: 514 AEQLRRELEEKEQERLDIEEKYTSLQEEAQGKTKKLKKVWT---MLMAAKSEMADLQQE- 569 Query: 195 DNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQ 338 H ++I L E++R+ S+ L L+ + DN + +D Q Sbjct: 570 ---------HQREIEGLLENIRQL-SRELRLQ---MLIIDNFIPRDYQ 604
>TAOK1_RAT (O88664) Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand| and one amino acid protein 1) Length = 1001 Score = 39.7 bits (91), Expect = 0.008 Identities = 51/203 (25%), Positives = 97/203 (47%), Gaps = 28/203 (13%) Frame = +3 Query: 21 KLKEQLHE-REKYILELEMKLNDTHRELDTLKIDHQA-------VWANQD------LLRE 158 KLK ++ E R + +LE + N+ E++ L HQA V AN++ + + Sbjct: 484 KLKAEMDEHRLRLDKDLETQRNNFAAEMEKLIKKHQASMEKEAKVMANEEKKFQQHIQAQ 543 Query: 159 QTNEIASFRRELDNSEAERAQHLKQ-IHDLQEHLREKESQYLALEE---QHRVAQD--NI 320 Q E+ SF R + LK+ +++ Q ++++ ++L+ ++ QH A++ N+ Sbjct: 544 QKKELNSFLESQKREYKLRKEQLKEELNENQSTPKKEKQEWLSKQKENIQHFQAEEEANL 603 Query: 321 LYKDEQLRDAHAWITRVQEMDILQSQSLQA-----ELRERTDQFGQCWATFQQQYVEMQQ 485 L + Q + R + +L +L+ EL +R Q A +Q+ MQ+ Sbjct: 604 LRRQRQYLELEC--RRFKRRMLLGRHNLEQDLVREELNKRQTQKDLEHAMLLRQHESMQE 661 Query: 486 ---GFLHTIQRLQLELIELRDRT 545 L+TIQ+++ ELI L+ +T Sbjct: 662 LEFRHLNTIQKMRCELIRLQHQT 684
>TAOK1_MOUSE (Q5F2E8) Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand| and one amino acid protein 1) Length = 1001 Score = 39.7 bits (91), Expect = 0.008 Identities = 51/203 (25%), Positives = 97/203 (47%), Gaps = 28/203 (13%) Frame = +3 Query: 21 KLKEQLHE-REKYILELEMKLNDTHRELDTLKIDHQA-------VWANQD------LLRE 158 KLK ++ E R + +LE + N+ E++ L HQA V AN++ + + Sbjct: 484 KLKAEMDEHRLRLDKDLETQRNNFAAEMEKLIKKHQAAMEKEAKVMANEEKKFQQHIQAQ 543 Query: 159 QTNEIASFRRELDNSEAERAQHLKQ-IHDLQEHLREKESQYLALEE---QHRVAQD--NI 320 Q E+ SF R + LK+ +++ Q ++++ ++L+ ++ QH A++ N+ Sbjct: 544 QKKELNSFLESQKREYKLRKEQLKEELNENQSTPKKEKQEWLSKQKENIQHFQAEEEANL 603 Query: 321 LYKDEQLRDAHAWITRVQEMDILQSQSLQA-----ELRERTDQFGQCWATFQQQYVEMQQ 485 L + Q + R + +L +L+ EL +R Q A +Q+ MQ+ Sbjct: 604 LRRQRQYLELEC--RRFKRRMLLGRHNLEQDLVREELNKRQTQKDLEHAMLLRQHESMQE 661 Query: 486 ---GFLHTIQRLQLELIELRDRT 545 L+TIQ+++ ELI L+ +T Sbjct: 662 LEFRHLNTIQKMRCELIRLQHQT 684
>MYSP_BLOTA (Q8MUF6) Paramyosin (Allergen Blo t 11)| Length = 875 Score = 39.3 bits (90), Expect = 0.010 Identities = 44/202 (21%), Positives = 86/202 (42%), Gaps = 29/202 (14%) Frame = +3 Query: 18 EKLKEQ----LHEREKY---ILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIA 176 EKL++Q E +K + E + +LND HR + +I+ + + ++ L E Sbjct: 413 EKLRDQKEALARENKKLADDLAEAKSQLNDAHRRIHEQEIEIKRLENEREELAAAYKEAE 472 Query: 177 SFRRELDNSEAERAQHLKQI-HDLQEHLREKESQYLALEEQH---------RVAQDNILY 326 + R++ + L Q HD ++ L +KE + AL +Q+ R+A+ Sbjct: 473 TLRKQEEAKNQRLTAELAQTRHDYEKRLAQKEEEIEALRKQYQIEIEQLNMRLAEAEAKL 532 Query: 327 KDEQLRDAHAWITRVQEMDILQSQS------LQAELRERTDQFGQCWATFQQQYVEMQQG 488 K E R + ++ E+++ + LQ ++++ Q A + + + ++QQ Sbjct: 533 KTEVARLKKKYQAQITELELSLDAANKANIDLQKTIKKQALQITGLQAHYDEVHRQLQQA 592 Query: 489 F------LHTIQRLQLELIELR 536 Q L EL E+R Sbjct: 593 VDQLGVTQRRCQALTAELEEMR 614 Score = 38.1 bits (87), Expect = 0.023 Identities = 42/189 (22%), Positives = 80/189 (42%), Gaps = 14/189 (7%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKID-HQAVWANQDLLREQTNEIASFRREL 194 E + +L + E+ LE + EL++LK+ + A +L R+ T Sbjct: 237 EDTRHRLEDEERKRSSLENHAHTLEVELESLKVQLEEESEARLELERQLTKANGDAASWK 296 Query: 195 DNSEAERAQHLKQIHDLQEHLREKESQY-----------LALEEQHRVAQD--NILYKDE 335 EAE H+ ++ +L+ + +K S+Y ALE+Q Q +L D Sbjct: 297 SKYEAELQAHVDEVEELRRKMAQKISEYGEQLEALLNKCSALEKQKARLQSEVEVLIMDL 356 Query: 336 QLRDAHAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQ 515 + AHA + E + Q + + +L+ + ++ Q+ + + +Q+LQ Sbjct: 357 EKATAHA---QALEKRVSQLEKINLDLKSKLEEVSMLLEQTQKDL----RVKIADLQKLQ 409 Query: 516 LELIELRDR 542 E +LRD+ Sbjct: 410 HEYEKLRDQ 418
>CEP72_MOUSE (Q9D3R3) Centrosomal protein of 72 kDa (Cep72 protein)| Length = 646 Score = 39.3 bits (90), Expect = 0.010 Identities = 34/152 (22%), Positives = 71/152 (46%), Gaps = 4/152 (2%) Frame = +3 Query: 21 KLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASF----RR 188 +L EQ + + ++ +LN+T RELDTL+ + D E+ + + S ++ Sbjct: 486 RLAEQQQQYTATVTKMTAELNNTKRELDTLR-------QHLDKSLEENSHLKSLLYNVKK 538 Query: 189 ELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITR 368 E+ ++ A L QI LQ +++ + + L +QH D I + L+++H+ + Sbjct: 539 EVKTADTSTALTL-QITGLQASMKQLSGEVVEL-KQHVEHYDKIQELTQMLQESHSSLVS 596 Query: 369 VQEMDILQSQSLQAELRERTDQFGQCWATFQQ 464 E + + +A+ R +Q + F++ Sbjct: 597 TNEHLLQELSRTRAQHRAEVEQMRWSFQEFKK 628
>RAD50_THEVO (P58302) DNA double-strand break repair rad50 ATPase| Length = 895 Score = 39.3 bits (90), Expect = 0.010 Identities = 26/86 (30%), Positives = 48/86 (55%), Gaps = 2/86 (2%) Frame = +3 Query: 165 NEIASFRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLR 344 NE+ S E+DN+ KQI +L+ LR E + ALEE+ + ++ + +E+L Sbjct: 190 NELQSKINEIDNNN-------KQIEELESKLRLIEPEIKALEEEINIKENKKDHLNEELH 242 Query: 345 DAHAWITRVQ--EMDILQSQSLQAEL 416 +A + ++ EM++ +SQS +A + Sbjct: 243 RLNAQLETIKKYEMELAESQSRKASI 268
>LAML3_XENLA (P10999) Lamin-L(III) (Lamin-B3)| Length = 583 Score = 39.3 bits (90), Expect = 0.010 Identities = 48/180 (26%), Positives = 76/180 (42%), Gaps = 13/180 (7%) Frame = +3 Query: 30 EQLHEREKYILELEMKLNDTHRELDTLKIDH-QAVWANQDLLREQTNEIASFRR-ELDNS 203 +QLH+ + ++LE K+ +LD K H Q V + + EI S RR E ++ Sbjct: 180 KQLHDEMLWRVDLENKMQTIREQLDFQKNIHTQEVKEIKKRHDTRIVEIDSGRRVEFESK 239 Query: 204 EAERAQHLKQIHDLQ-----EHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITR 368 AE Q L++ H+ Q EHL + S LE A N Y + A R Sbjct: 240 LAEALQELRRDHEQQILEYKEHLEKNFS--AKLENAQLAAAKNSDYASATREEIMATKLR 297 Query: 369 VQEMDI------LQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIE 530 V + Q+ +L+A++R+ D + ++Q E + Q LQ +L E Sbjct: 298 VDTLSSQLNHYQKQNSALEAKVRDLQDMLDRAHDMHRRQMTEKDREVTEIRQTLQGQLEE 357
>RAD50_METKA (Q8TXI4) DNA double-strand break repair rad50 ATPase| Length = 876 Score = 39.3 bits (90), Expect = 0.010 Identities = 43/180 (23%), Positives = 84/180 (46%), Gaps = 2/180 (1%) Frame = +3 Query: 15 AEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRREL 194 AE E ER + + + +L REL+ LK + + + + L+E+ NE+ +RE Sbjct: 180 AEAKLETFRERVRDLKGSKKELKRVERELEELKREVKELEPEVEELKERLNELREAKREF 239 Query: 195 DNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQ 374 + E E L+ + + E L+ + L E+ + A+ + ++L D ++V+ Sbjct: 240 ERLEGE----LRLLENKIESLKGRRDDLRKLVEEGKEAEREL----QRLGDVP---SKVR 288 Query: 375 EMDILQSQSLQAELRERTDQFGQCWATFQ--QQYVEMQQGFLHTIQRLQLELIELRDRTG 548 E+ ++ +AELR R ++ + + +E + L ++R EL EL+D G Sbjct: 289 EL-----ENEEAELRRRIEELRNLLDDLRSLRNRLESAEEELEGVKR---ELEELKDEAG 340
>MYH9_CHICK (P14105) Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle| myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A) Length = 1959 Score = 39.3 bits (90), Expect = 0.010 Identities = 55/223 (24%), Positives = 90/223 (40%), Gaps = 17/223 (7%) Frame = +3 Query: 3 HVVAAEKLKEQLHEREKYILELEMKLNDTHRELDTLKID-HQAVWANQDLLREQTNEIAS 179 H L+E+L EK ELE T R+L+ D H + Q + E +++ Sbjct: 1025 HEAMITDLEERLRREEKQRQELEK----TRRKLEGDSSDLHDQIAELQAQIAELKIQLSK 1080 Query: 180 FRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAW 359 EL + A + Q + + +RE ESQ L+E + + ++Q RD Sbjct: 1081 KEEELQAALARVEEEAAQKNMALKKIRELESQITELQEDLESERASRNKAEKQKRDLGEE 1140 Query: 360 I--TRVQEMDILQSQSLQAELRERTDQ--------FGQCWATFQQQYVEMQQGFLHTIQR 509 + + + D L S + Q ELR + +Q T + Q EM+Q I+ Sbjct: 1141 LEALKTELEDTLDSTAAQQELRSKREQEVTVLKKTLEDEAKTHEAQIQEMRQKHSQAIEE 1200 Query: 510 LQLELIEL-RDRTGEQDVSQAAQDGSAESS-----YVQSKGSS 620 L +L + R + + QA + AE S +Q KG + Sbjct: 1201 LAEQLEQTKRVKANLEKAKQALESERAELSNEVKVLLQGKGDA 1243 Score = 38.5 bits (88), Expect = 0.017 Identities = 30/143 (20%), Positives = 70/143 (48%), Gaps = 4/143 (2%) Frame = +3 Query: 6 VVAAEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFR 185 ++ + +E++ +E+ +++++ K L ++ + A + L+EQ A Sbjct: 837 LLQVSRQEEEMMAKEEELIKVKEKQLAAENRLSEMETFQAQLMAEKMQLQEQLQAEAELC 896 Query: 186 RELDNSEAE---RAQHLKQI-HDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAH 353 E + A + Q L++I HDL+ + E+E + L+ + + Q NI +EQL + Sbjct: 897 AEAEEIRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEE 956 Query: 354 AWITRVQEMDILQSQSLQAELRE 422 + ++Q L+ + +A+L++ Sbjct: 957 SARQKLQ----LEKVTTEAKLKK 975
>RAD50_MOUSE (P70388) DNA repair protein RAD50 (EC 3.6.-.-) (mRad50)| Length = 1312 Score = 38.9 bits (89), Expect = 0.013 Identities = 46/202 (22%), Positives = 93/202 (46%), Gaps = 21/202 (10%) Frame = +3 Query: 15 AEKLKEQLHEREKYILELEMKLNDTHRELD----------TLKIDHQAVWANQD------ 146 A++ +E + R+ I L TH ELD +K H+ V Q+ Sbjct: 357 ADRHQEHIRARDSLIQSLA-----THLELDGFERGPFSERQIKNFHELVKERQEREAKTA 411 Query: 147 --LLREQTNEIASFRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALE---EQHRVAQ 311 LL + T++ A +R+LD ++ + I E L +K+S+ + +Q + Sbjct: 412 SQLLSDLTDKEALKQRQLDELRDRKSGLGRTIELKTEILTKKQSELRHVRSELQQLEGSS 471 Query: 312 DNILYKDEQLRDAHAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGF 491 D IL D++L A +++ ++ +++ L+AE+ ++ + ++ EM+Q Sbjct: 472 DRILELDQELTKAERELSKAEKNSSIET--LKAEVMSLQNEKADLDRSLRKLDQEMEQLN 529 Query: 492 LHTIQRLQLELIELRDRTGEQD 557 HT R Q+E++ +D+T + + Sbjct: 530 HHTTTRTQMEML-TKDKTDKDE 550 Score = 37.0 bits (84), Expect = 0.051 Identities = 34/118 (28%), Positives = 57/118 (48%), Gaps = 13/118 (11%) Frame = +3 Query: 33 QLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDL-LREQTNEIASFRRELDNSEA 209 QL+E EK+ ++ + +++DT KI Q W +L LR++ R EL E Sbjct: 986 QLNECEKHREKINKDMGTMRQDIDTQKI--QERWLQDNLTLRKR-------RDELKEVEE 1036 Query: 210 ERAQHLKQIHDLQEHLREKESQYL-----ALEEQHRVA-------QDNILYKDEQLRD 347 E QHLK++ +Q + E Q L ++ H +A +D IL+ ++LR+ Sbjct: 1037 EPKQHLKEMGQMQVLQMKNEHQKLEENIDTIKRNHSLALGRQKGYEDEILHFKKELRE 1094 Score = 31.2 bits (69), Expect = 2.8 Identities = 22/116 (18%), Positives = 56/116 (48%) Frame = +3 Query: 27 KEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDNSE 206 ++ + ++++ I L+ K N+ E + + Q ++ E + E+ S RE+ +++ Sbjct: 850 RKLIQDQQEQIQHLKSKTNELKSEKLQIATNLQRRQQMEEQSVELSTEVQSLNREIKDAK 909 Query: 207 AERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQ 374 + + + LQ+ EKE +++AQD I E++++ H ++ ++ Sbjct: 910 EQISPLETALEKLQQ---EKEELIHRKHTSNKMAQDKINDIKEKVKNIHGYMKDIE 962
>GOGA4_HUMAN (Q13439) Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa| golgin) (Golgin-245) (Protein 72.1) Length = 2230 Score = 38.9 bits (89), Expect = 0.013 Identities = 45/202 (22%), Positives = 89/202 (44%), Gaps = 2/202 (0%) Frame = +3 Query: 21 KLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDN 200 K+KE L + + ELE +L E +TL I Q L E+ N+I S + ++++ Sbjct: 1259 KVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQ---LEEKENQIKSMKADIES 1315 Query: 201 SEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQEM 380 E+ K+ + Q+ EKES L+++ + + E+L++ I+ + + Sbjct: 1316 LVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQ 1375 Query: 381 DILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDRTGEQDV 560 L ++Q + + ++ ++QY E + L +Q L ++ D ++ + Sbjct: 1376 --LTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKV----DTLSKEKI 1429 Query: 561 SQAAQ--DGSAESSYVQSKGSS 620 S Q D S + S + K S Sbjct: 1430 SALEQVDDWSNKFSEWKKKAQS 1451 Score = 30.4 bits (67), Expect = 4.8 Identities = 19/80 (23%), Positives = 39/80 (48%), Gaps = 2/80 (2%) Frame = +3 Query: 189 ELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQH--RVAQDNILYKDEQLRDAHAWI 362 +L+++EA++ + I LQE L EK +Y + QH + N + + L + + Sbjct: 1779 KLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDV 1838 Query: 363 TRVQEMDILQSQSLQAELRE 422 + + L Q L+ +++E Sbjct: 1839 QKTLQEKELTCQILEQKIKE 1858
>MPP9_HUMAN (Q99550) M-phase phosphoprotein 9| Length = 692 Score = 38.9 bits (89), Expect = 0.013 Identities = 36/150 (24%), Positives = 68/150 (45%), Gaps = 19/150 (12%) Frame = +3 Query: 21 KLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDN 200 +L LHE + LE K N E++ L+ A + +L+E+ E+ + +E DN Sbjct: 293 QLDSALHEATSRVRTLENKNNLLEIEVNDLRERFSAASSASKILQERIEEMRTSSKEKDN 352 Query: 201 SEAERAQHLKQIHDLQEHLR----EKESQ--------------YLALEEQHRVAQDNILY 326 + L+ + + E+ +KE+Q Y +L ++HR +D + Sbjct: 353 TIIRLKSRLQDLEEAFENAYKLSDDKEAQLKQENKMFQDLLGEYESLGKEHRRVKDALNT 412 Query: 327 KDEQLRDAHAWITRVQEM-DILQSQSLQAE 413 + +L DA+ I+ ++ M L++Q Q E Sbjct: 413 TENKLLDAYTQISDLKRMISKLEAQVKQVE 442
>ATK1_ARATH (Q07970) Kinesin-1 (Kinesin-like protein A)| Length = 793 Score = 38.9 bits (89), Expect = 0.013 Identities = 39/183 (21%), Positives = 85/183 (46%), Gaps = 5/183 (2%) Frame = +3 Query: 9 VAAEKLKEQLHEREKYILELEMKLNDTHRELDTL--KIDHQAVWANQDLLREQTNEIASF 182 VAAEK++ L E + E +M L+ + ++ Q + QT ++ + Sbjct: 188 VAAEKVQASLGEELDKVKEEKMAAKQKVTSLEDMYKRLQEYNTSLQQYNSKLQT-DLETV 246 Query: 183 RRELDNSEAERAQHLKQIHDLQEH---LREKESQYLALEEQHRVAQDNILYKDEQLRDAH 353 R L +E E++ L+ + L+ H L+++ S L++ +D++L + LR+ Sbjct: 247 RAALTRAEKEKSSILENLSTLRGHSKSLQDQLSSSRVLQDDAIKQKDSLLSEVTNLRNEL 306 Query: 354 AWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIEL 533 + ++ ++QSQ L E+R+ + G+ ++ + + + G L LQ E + + Sbjct: 307 QQVRDDRDRQVVQSQKLSEEIRKYQENVGK--SSQELDILTAKSGSLEETCSLQKERLNM 364 Query: 534 RDR 542 ++ Sbjct: 365 LEQ 367
>CLPB2_STRAW (Q826F2) Chaperone clpB 2| Length = 879 Score = 38.9 bits (89), Expect = 0.013 Identities = 35/134 (26%), Positives = 62/134 (46%), Gaps = 17/134 (12%) Frame = +3 Query: 75 KLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDN-----SEAERAQHLK--- 230 +L + REL L+ + A A + R+ + R+EL+ EAERA L Sbjct: 445 RLEELRRELADLRGEADAKHAQWEAERQAIRRVQELRQELEQVRHEAEEAERAYDLNRAA 504 Query: 231 -----QIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAW----ITRVQEMD 383 ++ DL+ L +E Q A + ++R+ ++ ++ ++E AW + R+QE + Sbjct: 505 ELRYGRLQDLERRLAAEEEQLAAKQGENRLLRE-VVTEEEIAEIVAAWTGIPVARLQEGE 563 Query: 384 ILQSQSLQAELRER 425 + L LRER Sbjct: 564 REKLLRLDEILRER 577
>INVO_HYLLA (P17941) Involucrin| Length = 522 Score = 38.5 bits (88), Expect = 0.017 Identities = 36/146 (24%), Positives = 70/146 (47%), Gaps = 10/146 (6%) Frame = +3 Query: 159 QTNEIASFRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQH---RVAQDNI--- 320 Q + R+L+ E + QHL+Q + +HL E+E Q LE+Q V++ + Sbjct: 332 QLEHLVQQERQLEQQEG-KVQHLEQQVEQLKHLEEQEGQLKHLEQQQGQLEVSEQQVGQP 390 Query: 321 LYKDEQLRDAHAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQ----QYVEMQQG 488 + +++ + + ++ L+ Q Q EL E+ Q GQ QQ ++ E Q+G Sbjct: 391 KHLEQEGKQLELPEQQEGQLKHLEKQEAQLELPEQ--QVGQPKHPEQQEKQLEHPEQQEG 448 Query: 489 FLHTIQRLQLELIELRDRTGEQDVSQ 566 L +++ + +L +L + G+ + Q Sbjct: 449 QLKHLEQQEGQLKDLEQQKGQLEQQQ 474 Score = 37.0 bits (84), Expect = 0.051 Identities = 45/190 (23%), Positives = 82/190 (43%), Gaps = 7/190 (3%) Frame = +3 Query: 18 EKLKEQLHEREKYI---LELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRR 188 ++LK++ +R++ + LE E KL D + +K D Q + LL Sbjct: 106 QQLKQEKAQRDQQLNEHLEEEKKLLDQQLNQELIKRDEQLGIKKEQLL------------ 153 Query: 189 ELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITR 368 EL + + +HL+Q E ++E Q LE+Q + + + D+Q + + Sbjct: 154 ELTEQQEGQLEHLEQQEGQLELPEQQEGQLEHLEQQ----EGQLKHLDQQGKQPELPEQQ 209 Query: 369 VQEMDILQSQSLQAELRERTDQFGQCWATFQQ----QYVEMQQGFLHTIQRLQLELIELR 536 V ++ L+ Q + +L+ Q G+ +Q +Y+E Q+G Q L+ E + Sbjct: 210 VAQLKHLEQQ--EGQLKHLEHQKGELQVPEEQVGQLKYLEQQEG-----QLKHLDQQEKQ 262 Query: 537 DRTGEQDVSQ 566 EQ V Q Sbjct: 263 PELPEQQVGQ 272 Score = 31.6 bits (70), Expect = 2.1 Identities = 41/187 (21%), Positives = 83/187 (44%), Gaps = 5/187 (2%) Frame = +3 Query: 21 KLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRR---- 188 +L EQ + K++ + E +L + L++ + V L +Q ++ + Sbjct: 204 ELPEQQVAQLKHLEQQEGQLKHLEHQKGELQVPEEQV-GQLKYLEQQEGQLKHLDQQEKQ 262 Query: 189 -ELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWIT 365 EL + + +HL+Q EH+ +E Q L L EQ +V Q L ++++ + H Sbjct: 263 PELPEQQVGQLKHLEQQEGQLEHMEHQEGQ-LGLPEQ-QVGQLKQL-EEQEGQPKHLEEE 319 Query: 366 RVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDRT 545 Q ++Q + L ++ Q Q + Q++E Q L ++ + +L L + Sbjct: 320 EGQLKHLVQQEGQLEHLVQQERQLEQ--QEGKVQHLEQQVEQLKHLEEQEGQLKHLEQQQ 377 Query: 546 GEQDVSQ 566 G+ +VS+ Sbjct: 378 GQLEVSE 384
>TRIPB_HUMAN (Q15643) Thyroid receptor-interacting protein 11 (TRIP-11)| (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution related gene on chromosome 14) Length = 1979 Score = 38.5 bits (88), Expect = 0.017 Identities = 32/141 (22%), Positives = 72/141 (51%), Gaps = 7/141 (4%) Frame = +3 Query: 21 KLKEQLHEREKYILELEMKLNDTHRELDTLK---IDHQAVWANQDLLREQ-TNEIASFRR 188 KLK+ L++ +K + +LE D +ELD K I + + L +++ +++ + Sbjct: 531 KLKQDLNDEKKRVHQLEDDKMDITKELDVQKEKLIQSEVALNDLHLTKQKLEDKVENLVD 590 Query: 189 ELDNSEAERAQHLKQIHDLQEHLREKESQYLAL--EEQHRVAQD-NILYKDEQLRDAHAW 359 +L+ S+ K+ +L+EH+R+ E + + E + QD N +KD L++ A Sbjct: 591 QLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNELMQSLNQDSNSNFKDTLLKEREAE 650 Query: 360 ITRVQEMDILQSQSLQAELRE 422 + +++ ++ + + L L++ Sbjct: 651 VRNLKQ-NLSELEQLNENLKK 670 Score = 31.6 bits (70), Expect = 2.1 Identities = 29/148 (19%), Positives = 61/148 (41%), Gaps = 16/148 (10%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQ-----AVWANQDLLREQTNEIASF 182 E L++ + E+++ + ++ + N EL+ L+ + A D + E +E++ Sbjct: 842 EILRQTIEEKDRSLGSMKEENNHLQEELERLREEQSRTAPVADPKTLDSVTELASEVSQL 901 Query: 183 RRELDNSEAERAQHLKQIHD-----------LQEHLREKESQYLALEEQHRVAQDNILYK 329 ++ E E H K I D LQE +E + E+ + L K Sbjct: 902 NTIKEHLEEEIKHHQKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQMNATHTQLFLEK 961 Query: 330 DEQLRDAHAWITRVQEMDILQSQSLQAE 413 DE+++ I +++ + Q +Q + Sbjct: 962 DEEIKSLQKTIEQIKTQLHEERQDIQTD 989
>CEP2_HUMAN (Q9BV73) Centrosomal protein 2 (Centrosomal Nek2-associated protein| 1) (C-NAP1) (Centrosome protein 250) (Centrosome-associated protein CEP250) Length = 2442 Score = 38.5 bits (88), Expect = 0.017 Identities = 47/218 (21%), Positives = 97/218 (44%), Gaps = 21/218 (9%) Frame = +3 Query: 27 KEQLHEREKYILELEMKLNDTHRELDTLKI-----DHQAVWANQDL--LREQTN-EIASF 182 +E +HE ++ +LE +L HR++ + + + V Q L REQ + S Sbjct: 1742 QEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSL 1801 Query: 183 RRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEE-----QHRVAQDNILYKDE--QL 341 + +LD ++ AQ +++ LQ+ ++ + Q ++E Q + Q ++ K+ +L Sbjct: 1802 QSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGEL 1861 Query: 342 RDAHAWITRVQEMDILQSQSLQA------ELRERTDQFGQCWATFQQQYVEMQQGFLHTI 503 +D R++E ++ + +QA +LR + + + QQQ E Q Sbjct: 1862 QDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVET 1921 Query: 504 QRLQLELIELRDRTGEQDVSQAAQDGSAESSYVQSKGS 617 + LQ ++ + E+D A ++SS Q + + Sbjct: 1922 RALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAA 1959 Score = 36.2 bits (82), Expect = 0.087 Identities = 36/163 (22%), Positives = 71/163 (43%), Gaps = 10/163 (6%) Frame = +3 Query: 120 HQAVWANQ---DLLREQTNEIASFRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALE 290 HQ +W Q D+LR+Q ++ L ++EAE++Q ++ DLQ L + + + E Sbjct: 1249 HQDLWKTQQTRDVLRDQVQKL---EERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWE 1305 Query: 291 EQHRVAQDNILYKDEQLRDAHAWITRVQEMDILQSQS----LQAELRERTDQFGQCWATF 458 + + ++ E + + + R E+ +++Q LQA T Q A Sbjct: 1306 GKQNSLESELMELHETMASLQSRLRRA-ELQRMEAQGERELLQAAKENLTAQVEHLQAAV 1364 Query: 459 QQQYVEMQ-QGFLHTIQRLQLELIELRDR--TGEQDVSQAAQD 578 + + G L R ++L++ E++ +QA Q+ Sbjct: 1365 VEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQE 1407 Score = 33.1 bits (74), Expect = 0.73 Identities = 43/190 (22%), Positives = 84/190 (44%), Gaps = 14/190 (7%) Frame = +3 Query: 48 EKYILELEMKLNDTHRELDTLK-IDHQAVWANQDLLREQTNEIASFRRELDNSEAERAQH 224 E+ + ++++ L + REL T + + + + + Q + + L + E E Sbjct: 1682 EEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQ 1741 Query: 225 LKQIHDLQEHLREKESQYLALEEQHRVAQDNILY--KDEQLRDAHAWITRVQEMDILQSQ 398 + IH+LQE + E Q L +V + ++L +++++ + +E L+ Q Sbjct: 1742 QEHIHELQELKDQLEQQLQGLHR--KVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQ 1799 Query: 399 SLQAELRE------RTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLEL----IELRDRTG 548 SLQ++L E + DQ + QQQ ++ LQ L + L++R G Sbjct: 1800 SLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHG 1859 Query: 549 E-QDVSQAAQ 575 E QD + A+ Sbjct: 1860 ELQDHKEQAR 1869 Score = 33.1 bits (74), Expect = 0.73 Identities = 55/217 (25%), Positives = 94/217 (43%), Gaps = 41/217 (18%) Frame = +3 Query: 33 QLHEREKYILELEMKLNDTHRELDTLKI-------DHQAVWANQDLLRE-----QTNEIA 176 +L ++++ I ++ D ++L TL+ +H + Q L++E +T +A Sbjct: 1530 ELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVA 1589 Query: 177 SFRRELDNSEAERAQHLK----QIHDLQEH-------LREKESQYLALEEQ--------- 296 LD E R+Q L+ QIHDL+ H L+E++ + + EQ Sbjct: 1590 LTHLTLDLEE--RSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKE 1647 Query: 297 ------HRVAQDNILYKD--EQLRDAHAWITRVQEMDILQSQ-SLQAELRERTDQFGQCW 449 R Q+ +L K+ + L D T++ E D+ Q + SL+ RE T Q Sbjct: 1648 HLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQ----- 1702 Query: 450 ATFQQQYVEMQQGFLHTIQRLQLELIELRDRTGEQDV 560 Q+ E +G QR LE ++L R E++V Sbjct: 1703 RQLMQERAEEGKG-PSKAQRGSLEHMKLILRDKEKEV 1738
>NEB1_RAT (O35867) Neurabin-1 (Neurabin-I) (Neural tissue-specific| F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A) (p180) (PP1bp175) Length = 1095 Score = 38.5 bits (88), Expect = 0.017 Identities = 43/168 (25%), Positives = 75/168 (44%), Gaps = 4/168 (2%) Frame = +3 Query: 63 ELEMKLNDTHRELDTLKIDHQAVWANQ---DLLREQTNE-IASFRRELDNSEAERAQHLK 230 EL++K T E+ LK QA + +L + Q + I + + E+ + Sbjct: 683 ELQIKHAVTEAEIQKLKTKLQAAENEKVRWELEKNQLQQNIEENKERMVKLESYWIEAQT 742 Query: 231 QIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQEMDILQSQSLQA 410 H + EHL+E +SQY ALE+++ A+ L KD Q + E+D ++ Q ++ Sbjct: 743 LCHTVNEHLKETQSQYQALEKKYNKAKK--LIKDFQQK----------ELDFIRRQEVER 790 Query: 411 ELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDRTGEQ 554 + E + + VE+ QG I+ L+ E+ L + G Q Sbjct: 791 KKLEEVE---------KAHLVEV-QGLQVRIRDLEAEVFRLLKQNGTQ 828
>MAD1_ASHGO (Q754Z1) Spindle assembly checkpoint component MAD1 (Mitotic arrest| deficient protein 1) Length = 659 Score = 38.5 bits (88), Expect = 0.017 Identities = 36/139 (25%), Positives = 63/139 (45%), Gaps = 11/139 (7%) Frame = +3 Query: 204 EAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQEMD 383 EAE + + ++ L E L E+E + L+ Q RV Q + Y E++ + +QE Sbjct: 159 EAEIERQMGELRALAERLAEREDEVAGLKAQ-RVLQAHRSYSAEEVEELGVLRRTLQEQL 217 Query: 384 ILQSQSLQAEL-----------RERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIE 530 L + +A L R + QF Q + + +E + LQLE ++ Sbjct: 218 ALSKELERANLEQANELKRLRQRSESQQFLQLENSKLRARLEKTDALRQQLDDLQLENVQ 277 Query: 531 LRDRTGEQDVSQAAQDGSA 587 L+++ + +V QA DGS+ Sbjct: 278 LQEKLTKWEVYQA--DGSS 294
>KIF3A_MOUSE (P28741) Kinesin-like protein KIF3A (Microtubule plus end-directed| kinesin motor 3A) Length = 701 Score = 38.5 bits (88), Expect = 0.017 Identities = 37/168 (22%), Positives = 74/168 (44%) Frame = +3 Query: 21 KLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDN 200 K + +L REK +L+ + + +L L + + + DLL + + + L+ Sbjct: 448 KARAELERREKDLLKAQQEHQSLLEKLSAL--EKKVIVGGVDLLAKAEEQ----EKLLEE 501 Query: 201 SEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQEM 380 S E + ++ L++ L EKE + L +EE++ Q+ K ++L+ W Sbjct: 502 SNMELEERRRRAEQLRKELEEKEQERLDIEEKYTSLQEEAQGKTKKLK--KVWTM----- 554 Query: 381 DILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLEL 524 ++ ++S A+L QQ++ +G L I++L EL Sbjct: 555 -LMAAKSEMADL--------------QQEHQREIEGLLENIRQLSREL 587 Score = 30.8 bits (68), Expect = 3.6 Identities = 28/108 (25%), Positives = 52/108 (48%) Frame = +3 Query: 15 AEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRREL 194 AE+L+++L E+E+ L++E K E + VW +L +E+A ++E Sbjct: 513 AEQLRKELEEKEQERLDIEEKYTSLQEEAQGKTKKLKKVWT---MLMAAKSEMADLQQE- 568 Query: 195 DNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQ 338 H ++I L E++R+ S+ L L+ + DN + +D Q Sbjct: 569 ---------HQREIEGLLENIRQL-SRELRLQ---MLIIDNFIPQDYQ 603
>TAOK1_HUMAN (Q7L7X3) Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand| and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B) Length = 1001 Score = 38.5 bits (88), Expect = 0.017 Identities = 50/203 (24%), Positives = 97/203 (47%), Gaps = 28/203 (13%) Frame = +3 Query: 21 KLKEQLHE-REKYILELEMKLNDTHRELDTLKIDHQA-------VWANQD------LLRE 158 KLK ++ E R + +LE + N+ E++ L HQA V +N++ + + Sbjct: 484 KLKAEMDEHRLRLDKDLETQRNNFAAEMEKLIKKHQAAMEKEAKVMSNEEKKFQQHIQAQ 543 Query: 159 QTNEIASFRRELDNSEAERAQHLKQ-IHDLQEHLREKESQYLALEE---QHRVAQD--NI 320 Q E+ SF R + LK+ +++ Q ++++ ++L+ ++ QH A++ N+ Sbjct: 544 QKKELNSFLESQKREYKLRKEQLKEELNENQSTPKKEKQEWLSKQKENIQHFQAEEEANL 603 Query: 321 LYKDEQLRDAHAWITRVQEMDILQSQSLQA-----ELRERTDQFGQCWATFQQQYVEMQQ 485 L + Q + R + +L +L+ EL +R Q A +Q+ MQ+ Sbjct: 604 LRRQRQYLELEC--RRFKRRMLLGRHNLEQDLVREELNKRQTQKDLEHAMLLRQHESMQE 661 Query: 486 ---GFLHTIQRLQLELIELRDRT 545 L+TIQ+++ ELI L+ +T Sbjct: 662 LEFRHLNTIQKMRCELIRLQHQT 684
>KINH_LOLPE (P21613) Kinesin heavy chain| Length = 967 Score = 38.5 bits (88), Expect = 0.017 Identities = 26/114 (22%), Positives = 58/114 (50%), Gaps = 4/114 (3%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELD 197 EKLKEQ+ E+E I + + R+ + L+ D + A+ + +++ E+ EL Sbjct: 441 EKLKEQMMEQEDLIAQ-------SRRDYENLQQDMSRIQADNESAKDEVKEVLQALEELA 493 Query: 198 NSEAERAQHL----KQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRD 347 + +++Q + K+ +L E L +K S +L+ + +D+ ++ +++ D Sbjct: 494 MNYDQKSQEVEDKNKENENLSEELNQKLSTLNSLQNELDQLKDSSMHHRKRVTD 547 Score = 37.7 bits (86), Expect = 0.030 Identities = 34/148 (22%), Positives = 66/148 (44%), Gaps = 4/148 (2%) Frame = +3 Query: 3 HVVAAEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASF 182 H L+E + + E LE ++ + E LK Q A ++T++ + Sbjct: 636 HEAKMASLQEAIKDSENKKRMLEDNVDSLNEEYAKLKAQEQMHLAALSEREKETSQASET 695 Query: 183 RRELDNS-EAERAQHLKQIHDLQEHLREKESQYLALEEQHR---VAQDNILYKDEQLRDA 350 R L+ E R QH KQ+ L++ + EK++ L++ ++ +A + + ++L+ Sbjct: 696 REVLEKQMEMHREQHQKQLQSLRDEISEKQATVDNLKDDNQRLSLALEKLQADYDKLKQ- 754 Query: 351 HAWITRVQEMDILQSQSLQAELRERTDQ 434 V++ L SLQ + RE+ Q Sbjct: 755 ----EEVEKAAKLADLSLQIDRREQAKQ 778 Score = 30.8 bits (68), Expect = 3.6 Identities = 37/184 (20%), Positives = 79/184 (42%) Frame = +3 Query: 12 AAEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRE 191 + EK++E+ YI +++ ++ + L+ Q + +I + ++ Sbjct: 576 SGEKIEEEFTVARLYISKMKSEVKTLVSRNNQLENTQQ----------DNFKKIETHEKD 625 Query: 192 LDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRV 371 L N + QH ++ LQE +++ E+ + R+ +DN+ + L + +A + Sbjct: 626 LSNCKLLIQQHEAKMASLQEAIKDSEN-------KKRMLEDNV----DSLNEEYAKLKAQ 674 Query: 372 QEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDRTGE 551 ++M + A L ER + Q T + +M+ +H Q Q +L LRD E Sbjct: 675 EQMHL-------AALSEREKETSQASETREVLEKQME---MHREQH-QKQLQSLRDEISE 723 Query: 552 QDVS 563 + + Sbjct: 724 KQAT 727
>RAD50_HUMAN (Q92878) DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50)| Length = 1312 Score = 38.1 bits (87), Expect = 0.023 Identities = 31/137 (22%), Positives = 61/137 (44%), Gaps = 1/137 (0%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELD 197 E+L + H ++ + E E KL D HREL+ L + + LL ++ +E+ Sbjct: 302 EQLNDLYHNHQRTVREKERKLVDCHRELEKLNKESR-------LLNQEKSELL------- 347 Query: 198 NSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRV-AQDNILYKDEQLRDAHAWITRVQ 374 E+ + Q QEH+R ++S +L Q + + + + Q+++ H + Q Sbjct: 348 ---VEQGRLQLQADRHQEHIRARDSLIQSLATQLELDGFERGPFSERQIKNFHKLVRERQ 404 Query: 375 EMDILQSQSLQAELRER 425 E + + L + E+ Sbjct: 405 EGEAKTANQLMNDFAEK 421 Score = 29.6 bits (65), Expect = 8.1 Identities = 30/132 (22%), Positives = 59/132 (44%), Gaps = 9/132 (6%) Frame = +3 Query: 78 LNDTHRELDTLKIDHQAVWANQDLLREQT----NEIASFRRELDNSEAERAQHLKQIHDL 245 L T EL + K+ + L EQT E+ S RE+ +++ E+ L+ L Sbjct: 863 LKSTTNELKSEKLQISTNLQRRQQLEEQTVELSTEVQSLYREIKDAK-EQVSPLETT--L 919 Query: 246 QEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQE-----MDILQSQSLQA 410 ++ +EKE +++AQD + E++++ H ++ ++ D + Q + Sbjct: 920 EKFQQEKEELINKKNTSNKIAQDKLNDIKEKVKNIHGYMKDIENYIQDGKDDYKKQK-ET 978 Query: 411 ELRERTDQFGQC 446 EL + Q +C Sbjct: 979 ELNKVIAQLSEC 990
>PLEC1_RAT (P30427) Plectin-1 (PLTN) (PCN)| Length = 4687 Score = 38.1 bits (87), Expect = 0.023 Identities = 51/205 (24%), Positives = 86/205 (41%), Gaps = 18/205 (8%) Frame = +3 Query: 27 KEQLHEREKYILELEMKLNDTHRE--LDTLKIDHQAVWANQDLLREQTNEIASF----RR 188 K+ L +RE++I + + KL ++ ++ + Q + +E+ +AS RR Sbjct: 2639 KDSLLQRERFIEQEKAKLEQLFQDEVAKAKQLQEEQQRQQQQMEQEKQELVASMEEARRR 2698 Query: 189 ELDNSEA-----ERAQHLKQIHDLQEHLREKESQYLA-----LEEQHRVAQDNILYKDEQ 338 + + E E Q L+Q QE L +E+Q L LEE+HR A L E+ Sbjct: 2699 QREAEEGVRRKQEELQRLEQQRQQQEKLLAEENQRLRERLQRLEEEHRAA----LAHSEE 2754 Query: 339 LRDAHAWITRV--QEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRL 512 + + A T+ D L S++AE + Q QQ E + +QRL Sbjct: 2755 IATSQAAATKALPNGRDALDGPSMEAEPEYTFEGLRQ--KVPAQQLQEAGILSMEELQRL 2812 Query: 513 QLELIELRDRTGEQDVSQAAQDGSA 587 + + T +DV + GS+ Sbjct: 2813 TQGHTTVAELTQREDVRHYLKGGSS 2837
>MYS_AEQIR (P24733) Myosin heavy chain, striated muscle| Length = 1938 Score = 38.1 bits (87), Expect = 0.023 Identities = 44/202 (21%), Positives = 88/202 (43%), Gaps = 15/202 (7%) Frame = +3 Query: 18 EKLKEQLHEREKYILE-----------LEMKLNDTHRELDTL---KIDHQA-VWANQDLL 152 E++K++L E+ +LE LE + D ++ L K D ++ + ++ L Sbjct: 864 ERIKKELEEQNVTLLEQKNDLFLQLQTLEDSMGDQEERVEKLIMQKADFESQIKELEERL 923 Query: 153 REQTNEIASFRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKD 332 ++ + A EA+ A K I DL+ L++ E + Q Q I +D Sbjct: 924 LDEEDAAADLEGIKKKMEADNANLKKDIGDLENTLQKAEQDKAHKDNQISTLQGEISQQD 983 Query: 333 EQLRDAHAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRL 512 E + + ++E + S SLQAE ++ + + A +Q E++ L +++ Sbjct: 984 EHIGKLNKEKKALEEANKKTSDSLQAE-EDKCNHLNKLKAKLEQALDELEDN-LEREKKV 1041 Query: 513 QLELIELRDRTGEQDVSQAAQD 578 + + +E R EQD+ ++ Sbjct: 1042 RGD-VEKAKRKVEQDLKSTQEN 1062
>NEB1_HUMAN (Q9ULJ8) Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin| binding protein I) (Protein phosphatase 1 regulatory subunit 9A) Length = 1098 Score = 38.1 bits (87), Expect = 0.023 Identities = 47/170 (27%), Positives = 74/170 (43%), Gaps = 6/170 (3%) Frame = +3 Query: 63 ELEMKLNDTHRELDTLKIDHQAV------WANQDLLREQTNEIASFRRELDNSEAERAQH 224 EL++K T E+ LK QA W + +Q E R S AQ Sbjct: 682 ELQIKHAVTEAEIQKLKTKLQAAENEKVRWELEKTQLQQNIEENKERMLKLESYWIEAQT 741 Query: 225 LKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQEMDILQSQSL 404 L H + EHL+E +SQY ALE+++ A+ L KD Q + E+D ++ Q Sbjct: 742 L--CHTVNEHLKETQSQYQALEKKYNKAKK--LIKDFQQK----------ELDFIKRQ-- 785 Query: 405 QAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDRTGEQ 554 +AE ++ D ++ ++ QG I+ L+ E+ L + G Q Sbjct: 786 EAERKKIED--------LEKAHLVEVQGLQVRIRDLEAEVFRLLKQNGTQ 827
>MLP1_YEAST (Q02455) Protein MLP1 (Myosin-like protein 1)| Length = 1875 Score = 38.1 bits (87), Expect = 0.023 Identities = 41/207 (19%), Positives = 85/207 (41%), Gaps = 17/207 (8%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKID-HQAVWANQDLLREQ----TNEIASF 182 +KLK+ + E + L+ + + +EL K + H+ +QD+L + +++ Sbjct: 1245 DKLKQNVAPIESELTALKYSMQEKEQELKLAKEEVHRWKKRSQDILEKHEQLSSSDYEKL 1304 Query: 183 RRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRD----- 347 E++N + E +Q + +E Q + +++QD++ + LRD Sbjct: 1305 ESEIENLKEELENKERQGAEAEEKFNRLRRQAQERLKTSKLSQDSLTEQVNSLRDAKNVL 1364 Query: 348 ------AHAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQR 509 A+A I +Q + Q + +R+ + + Q + E + TI Sbjct: 1365 ENSLSEANARIEELQNAKVAQGNNQLEAIRKLQEDAEKASRELQAKLEESTTSYESTING 1424 Query: 510 LQLELIELRDRTGEQ-DVSQAAQDGSA 587 L E+ L++ +Q + Q Q SA Sbjct: 1425 LNEEITTLKEEIEKQRQIQQQLQATSA 1451 Score = 34.3 bits (77), Expect = 0.33 Identities = 33/139 (23%), Positives = 66/139 (47%), Gaps = 27/139 (19%) Frame = +3 Query: 6 VVAAEKLKEQLHEREKYILELEMKLNDTHRELDTLKID---HQAVWANQDLLREQTNEI- 173 V AE+ + L ++ I ++++L D +LD +++ H ++ D + E+ N++ Sbjct: 1161 VTVAERDAKMLRQK---ISLMDVELQDARTKLDNSRVEKENHSSIIQQHDDIMEKLNQLN 1217 Query: 174 ------ASFRRELDNSEAERAQHLKQIHDLQEH--------------LREKESQY-LALE 290 + R EL+N+ ++ + ++ L+++ ++EKE + LA E Sbjct: 1218 LLRESNITLRNELENNNNKKKELQSELDKLKQNVAPIESELTALKYSMQEKEQELKLAKE 1277 Query: 291 EQHR--VAQDNILYKDEQL 341 E HR +IL K EQL Sbjct: 1278 EVHRWKKRSQDILEKHEQL 1296 Score = 31.2 bits (69), Expect = 2.8 Identities = 24/103 (23%), Positives = 49/103 (47%), Gaps = 12/103 (11%) Frame = +3 Query: 24 LKEQLHEREKYILELEMKLN----DTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRE 191 L+++L + + L K + D EL+ L+ D Q N D+L+++ NE++ +E Sbjct: 214 LEKELRSKNEQYLSYRQKTDKVILDIRNELNRLRNDFQMERTNNDVLKQKNNELSKSLQE 273 Query: 192 --------LDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQ 296 D+ +E+ + ++ Q + ESQ A++E+ Sbjct: 274 KLLEIKGLSDSLNSEKQEFSAEMSLKQRLVDLLESQLNAVKEE 316
>HMMR_HUMAN (O75330) Hyaluronan mediated motility receptor (Intracellular| hyaluronic acid-binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen) Length = 724 Score = 38.1 bits (87), Expect = 0.023 Identities = 45/212 (21%), Positives = 97/212 (45%), Gaps = 11/212 (5%) Frame = +3 Query: 21 KLKEQLHEREKYILELEMKLNDT----HRELDTLKIDHQAVWANQDLLREQTNEIASFRR 188 +L+E L E+ IL L+ L + ++++ L + Q L +E+ + + R Sbjct: 256 QLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQL------LEKEKEDHVNRNRE 309 Query: 189 ELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDA-HAWIT 365 +N AE Q+LKQ L++ REK +Q + D++L ++++L + H + Sbjct: 310 HNENLNAEM-QNLKQKFILEQQEREK-------LQQKELQIDSLLQQEKELSSSLHQKLC 361 Query: 366 RVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQR------LQLELI 527 QE + + + EL++ D+ + QQ E + + ++ +L+L+ Sbjct: 362 SFQEEMVKEKNLFEEELKQTLDELDKL-----QQKEEQAERLVKQLEEEAKSRAEELKLL 416 Query: 528 ELRDRTGEQDVSQAAQDGSAESSYVQSKGSSM 623 E + + E ++ +++ + + +Q K SM Sbjct: 417 EEKLKGKEAELEKSSAAHTQATLLLQEKYDSM 448 Score = 33.9 bits (76), Expect = 0.43 Identities = 40/182 (21%), Positives = 80/182 (43%), Gaps = 8/182 (4%) Frame = +3 Query: 30 EQLHEREKYILELEM--KLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDNS 203 E + ++K+ILE + KL ++D+L + ++L ++ SF+ E+ Sbjct: 317 EMQNLKQKFILEQQEREKLQQKELQIDSL------LQQEKELSSSLHQKLCSFQEEMVKE 370 Query: 204 EAERAQHLKQIHDLQEHLREKESQ----YLALEEQHRVAQDNILYKDEQLRDAHAWITRV 371 + + LKQ D + L++KE Q LEE+ + + + +E+L+ A Sbjct: 371 KNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEA----- 425 Query: 372 QEMDILQSQSLQAE--LRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDRT 545 E++ + QA L+E+ D Q Q+ + I+ L+LE L+++ Sbjct: 426 -ELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKLENSSLQEKA 484 Query: 546 GE 551 + Sbjct: 485 AK 486
>CEP2_MOUSE (Q60952) Centrosomal protein 2 (Intranuclear matrix protein)| (Fragment) Length = 609 Score = 38.1 bits (87), Expect = 0.023 Identities = 37/135 (27%), Positives = 64/135 (47%), Gaps = 3/135 (2%) Frame = +3 Query: 18 EKLKE---QLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRR 188 E LKE + +RE+ IL L + +HR L K Q + A Q+L R QT Sbjct: 274 ESLKELQLTVAQREEEILMLREASSPSHRALPAEKPALQPLPAQQELERLQT-------- 325 Query: 189 ELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITR 368 L +EA + ++ DL L + ++ +L+E Q ++L ++ + + R Sbjct: 326 ALRQTEAREIEWREKAQDLALSLAQSKASISSLQEITMFLQASVLERESEQQ-------R 378 Query: 369 VQEMDILQSQSLQAE 413 +QE +L SQ+L+ + Sbjct: 379 LQEELVLSSQALEEQ 393 Score = 35.8 bits (81), Expect = 0.11 Identities = 36/142 (25%), Positives = 58/142 (40%), Gaps = 1/142 (0%) Frame = +3 Query: 6 VVAAEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFR 185 V AE L+E L + + + E E L + TL+ A+ A D + + ++ Sbjct: 147 VSQAEALQEALSKAQAALQEKEQSLLEQAELSHTLEASTAALQATLDTCQARARQLEEAL 206 Query: 186 RELDNS-EAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWI 362 R + +A+ QH + LQ+ L +KE + L E+ A Sbjct: 207 RIREGEIQAQALQHHEVTQHLQQELCQKEEELRQLLEK-------------------AGA 247 Query: 363 TRVQEMDILQSQSLQAELRERT 428 R QE I + QSL+ E +E T Sbjct: 248 RRSQENGIQEKQSLEQERQEET 269
>ATI1_VACCV (P24759) 94 kDa A-type inclusion protein (ATI)| Length = 724 Score = 38.1 bits (87), Expect = 0.023 Identities = 36/158 (22%), Positives = 70/158 (44%) Frame = +3 Query: 150 LREQTNEIASFRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYK 329 LR E ++ +LD ++ + ++KQI L+ + + + L R ++ + Sbjct: 561 LRRDIKECDKYKEDLDKAKTTISNYVKQISTLESEIAKYQQDRDTLSVVRRELEEERRVR 620 Query: 330 DEQLRDAHAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQR 509 D + R TR QE D + +L++ +RE ++ C +E G L I R Sbjct: 621 DLESRLDEC--TRNQE-DTQEVDALRSRIRELENKLTDC--------IESGGGNLTEISR 669 Query: 510 LQLELIELRDRTGEQDVSQAAQDGSAESSYVQSKGSSM 623 LQ ++ +L + E ++ + E S +QS+ S + Sbjct: 670 LQSKISDLERQLSE------CRENATEISRLQSRISDL 701
>SMC2_MOUSE (Q8CG48) Structural maintenance of chromosome 2-like 1 protein| (Chromosome-associated protein E) (XCAP-E homolog) (FGF-inducible protein 16) Length = 1191 Score = 37.7 bits (86), Expect = 0.030 Identities = 29/138 (21%), Positives = 66/138 (47%), Gaps = 3/138 (2%) Frame = +3 Query: 228 KQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQEMDILQSQSLQ 407 +++ D+Q+ LR KE++ ALEE+ N+ K QL+ W + +E D+LQ++ Q Sbjct: 679 QEVKDVQDELRTKENELRALEEE-LAGLKNVAEKYRQLK--QQWEMKTEEGDLLQTKLQQ 735 Query: 408 AELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRL---QLELIELRDRTGEQDVSQAAQD 578 + ++ ++ T ++ ++ IQ+ + E +E + + E + + +D Sbjct: 736 SSYHKQQEELDALKKTIEESEETLKS--TKEIQKKAEEKYEALENKMKNAEAEREKELKD 793 Query: 579 GSAESSYVQSKGSSMACK 632 + ++K + + K Sbjct: 794 AQKKLDCAKTKADASSKK 811 Score = 30.4 bits (67), Expect = 4.8 Identities = 26/104 (25%), Positives = 49/104 (47%) Frame = +3 Query: 12 AAEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRE 191 +++K+KE+ E E LELE LK +H +N+ L I ++ + Sbjct: 808 SSKKMKEKQQEVEAITLELE-----------ELKREHA---SNEQQLDAVNEAIKAYEGQ 853 Query: 192 LDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNIL 323 ++ AE A++ + ++ Q+ L + ++Q AQDNI+ Sbjct: 854 IEKMAAEVAKNKESVNKAQDELMK--------QKQIITAQDNII 889
>SMC2_HUMAN (O95347) Structural maintenance of chromosome 2-like 1 protein| (Chromosome-associated protein E) (hCAP-E) (XCAP-E homolog) Length = 1197 Score = 37.7 bits (86), Expect = 0.030 Identities = 30/138 (21%), Positives = 66/138 (47%), Gaps = 3/138 (2%) Frame = +3 Query: 228 KQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQEMDILQSQSLQ 407 +++ D+Q+ LR KE++ ALEE+ N K QL+ W + +E D+LQ++ Q Sbjct: 679 QELKDVQDELRIKENELRALEEE-LAGLKNTAEKYRQLK--QQWEMKTEEADLLQTKLQQ 735 Query: 408 AELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRL---QLELIELRDRTGEQDVSQAAQD 578 + ++ ++ T ++ ++ IQR + E++E + + E + + +D Sbjct: 736 SSYHKQQEELDALKKTIEESEETLKN--TKEIQRKAEEKYEVLENKMKNAEAERERELKD 793 Query: 579 GSAESSYVQSKGSSMACK 632 + ++K + + K Sbjct: 794 AQKKLDCAKTKADASSKK 811
>SMC6_SCHPO (P53692) Structural maintenance of chromosome 6 (DNA repair protein| rad18) Length = 1140 Score = 37.7 bits (86), Expect = 0.030 Identities = 46/182 (25%), Positives = 89/182 (48%), Gaps = 24/182 (13%) Frame = +3 Query: 138 NQDLLREQTNEIASFRRELDNSEAERAQHLKQIHDLQ-EHLREKESQYLALEEQHRVAQD 314 +Q+L T +I + R + +E E + Q+ D + E R +++Q +EE R+ ++ Sbjct: 776 SQELSVLDTEKIQTLERRISETEKELESYAGQLQDAKNEEHRIRDNQRPVIEEI-RIYRE 834 Query: 315 NILYKDEQLRDAHAWITRVQ------EMDILQS----QSLQAELRERTDQFGQCWATF-- 458 I + ++L ++R++ E+DI + +S LRE+ + QC Sbjct: 835 KIQTETQRLSSLQTELSRLRDEKRNSEVDIERHRQTVESCTNILREKEAKKVQCAQVVAD 894 Query: 459 ---------QQQYVEMQQGFL-HTIQRLQLELIELRDRTGEQDVSQAAQDG-SAESSYVQ 605 ++ V++ L + I+RLQ+++ E R+RTG V QAA+D +A+ + Q Sbjct: 895 YTAKANTRCERVPVQLSPAELDNEIERLQMQIAEWRNRTG-VSVEQAAEDYLNAKEKHDQ 953 Query: 606 SK 611 +K Sbjct: 954 AK 955
>CENPE_HUMAN (Q02224) Centromeric protein E (CENP-E protein)| Length = 2663 Score = 37.7 bits (86), Expect = 0.030 Identities = 50/220 (22%), Positives = 90/220 (40%), Gaps = 30/220 (13%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEM-------KLNDTHRELDTLKIDHQAVWANQDLLREQTNEIA 176 E+LKEQL R+ + +E KL T E+ TL + + Q+ L+ + +++ Sbjct: 890 EQLKEQLENRDSPLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLK 949 Query: 177 S-----------FRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNIL 323 S + +L N+ QH + I+ L+ + E+ S+ L +EE +D Sbjct: 950 SDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQ 1009 Query: 324 YK--------DEQLRDAHAWITRVQEMDILQSQ----SLQAELRERTDQFGQCWATFQQQ 467 K D + ++ V++ +I++ Q SL E E A +Q Sbjct: 1010 QKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQL 1069 Query: 468 YVEMQQGFLHTIQRLQLELIELRDRTGEQDVSQAAQDGSA 587 ++++ TI+ Q EL L D +Q A + A Sbjct: 1070 KTDLKENIEMTIEN-QEELRLLGDELKKQQEIVAQEKNHA 1108 Score = 37.4 bits (85), Expect = 0.039 Identities = 34/155 (21%), Positives = 71/155 (45%), Gaps = 27/155 (17%) Frame = +3 Query: 18 EKLKEQLHEREKYI-------LELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIA 176 E LK +L +E + LEL KLN+ + E+ ++ + + + Q + + + Sbjct: 1161 ENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLR 1220 Query: 177 SFRRELDNSEAERAQHLKQIH-----------DLQEHLREKESQYL---ALEEQHRVAQD 314 + RE++ + + + LK H +L+ + EK +Q + LE+ H Q+ Sbjct: 1221 GYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQE 1280 Query: 315 NI--LYKDEQLRDAHAWITRVQ----EMDILQSQS 401 I L+++++L ++ Q E+++L QS Sbjct: 1281 EIPVLHEEQELLPNVKKVSETQETMNELELLTEQS 1315 Score = 35.0 bits (79), Expect = 0.19 Identities = 41/178 (23%), Positives = 76/178 (42%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELD 197 E L+ + + ++ I E+ K +T EL K+ H L+EQ I R L Sbjct: 1452 EVLQSESDQLKENIKEIVAKHLETEEEL---KVAHCC-------LKEQEETINELRVNLS 1501 Query: 198 NSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQE 377 E E + KQ+ + + L+ K + EEQ + Q I E + + + + Sbjct: 1502 EKETEISTIQKQLEAINDKLQNKIQEIYEKEEQLNIKQ--ISEVQENVNELKQFKEHRKA 1559 Query: 378 MDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDRTGE 551 D QS+++++ E T++ + Q E ++ + LQ+E +L++ T E Sbjct: 1560 KD-SALQSIESKMLELTNRLQESQEEIQIMIKEKEE-MKRVQEALQIERDQLKENTKE 1615 Score = 32.7 bits (73), Expect = 0.96 Identities = 51/218 (23%), Positives = 90/218 (41%), Gaps = 13/218 (5%) Frame = +3 Query: 9 VAAEKLKEQLHEREKYILELEMK----LNDTHRELDTLKID---HQAVWANQDLLREQTN 167 V ++LKE + E I E + K LN ++ +T KI Q + LLR + Sbjct: 1363 VKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEI- 1421 Query: 168 EIASFRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRD 347 E+ + L S E K+ DLQ +S+ L+E + L +E+L+ Sbjct: 1422 EMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKV 1481 Query: 348 AHAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRL----- 512 AH + +E L+ L E+ + +T Q+Q + + IQ + Sbjct: 1482 AHCCLKEQEE----TINELRVNLSEKETEI----STIQKQLEAINDKLQNKIQEIYEKEE 1533 Query: 513 QLELIELRD-RTGEQDVSQAAQDGSAESSYVQSKGSSM 623 QL + ++ + + ++ Q + A+ S +QS S M Sbjct: 1534 QLNIKQISEVQENVNELKQFKEHRKAKDSALQSIESKM 1571 Score = 30.0 bits (66), Expect = 6.2 Identities = 37/147 (25%), Positives = 74/147 (50%), Gaps = 12/147 (8%) Frame = +3 Query: 30 EQLHEREKYILELEMKLND-THRELDTL-KIDHQAVWANQDLLREQTNEIASFRRELDNS 203 +++ E ++ + ELE+ T ++ TL +I+ + + N+ +E EI S +E DN Sbjct: 1296 KKVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKF-QESQEEIKSLTKERDNL 1354 Query: 204 EAERAQHLKQIHD-LQEHLRE-----KESQYLALEEQHRVAQDN----ILYKDEQLRDAH 353 + + + L+ HD L+EH+RE +ESQ + + +DN I+ + EQ + Sbjct: 1355 KTIK-EALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKD 1413 Query: 354 AWITRVQEMDILQSQSLQAELRERTDQ 434 + + R++ ++ L L+E D+ Sbjct: 1414 SALLRIE----IEMLGLSKRLQESHDE 1436
>CYTSA_XENTR (Q2KN96) Cytospin-A| Length = 1101 Score = 37.7 bits (86), Expect = 0.030 Identities = 47/208 (22%), Positives = 96/208 (46%), Gaps = 10/208 (4%) Frame = +3 Query: 15 AEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRREL 194 AE+L+ L E + ++ +LN + L K+ D L +Q++++ F R+L Sbjct: 389 AEELQATLQELAD-LQQITQELNSENERLGEEKV------ILMDSLCQQSDKLELFSRQL 441 Query: 195 DNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWIT--- 365 + ++A +H + L E L K S+YL LE+++ +N ++ EQL ++ Sbjct: 442 EYAQALLDEH-HIAYSLDEDL--KSSRYLDLEQRYMDLAENGRFEREQLLGVQQHLSNSL 498 Query: 366 RVQEMDILQSQSLQAELRERT---DQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELR 536 ++ E D +Q + L+ER ++ + +Q + + T+ Q E L+ Sbjct: 499 KMAEQDNKDAQDVIRALKERNHHMERIAEAEQLSKQALAATLEEYKATLNSEQGECARLK 558 Query: 537 DRTGEQDVSQAAQ----DGSAESSYVQS 608 EQ+ + A+ S ++S++Q+ Sbjct: 559 ALL-EQEKQRVAELYSIHSSGDASHIQN 585
>SNX23_HUMAN (Q96L93) Kinesin-like motor protein C20orf23 (Sorting nexin 23)| Length = 1317 Score = 37.7 bits (86), Expect = 0.030 Identities = 42/193 (21%), Positives = 82/193 (42%), Gaps = 20/193 (10%) Frame = +3 Query: 21 KLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDN 200 KLK+ L E+EK+ + R + +I+ Q ++ E+ + +N Sbjct: 668 KLKDLLAEKEKF---------EEERLREQQEIELQKKRQEEETFLRVQEELQRLKELNNN 718 Query: 201 SEAERAQHLKQIHDLQEHLREKESQYL-------ALEEQHRVAQDNILYKDEQLRDAHAW 359 +AE+ Q +++ LQ +EK+ QY LEEQ + + + +EQLR+ Sbjct: 719 EKAEKFQIFQELDQLQ---KEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQEM 775 Query: 360 ITRVQEMD-------------ILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHT 500 I ++ + I +S E R D+ G+ Q ++ E ++ L Sbjct: 776 IQLLRRGEVQWVEEEKRDLEGIRESLLRVKEARAGGDEDGEELEKAQLRFFEFKRRQLVK 835 Query: 501 IQRLQLELIELRD 539 + L+ +L++ +D Sbjct: 836 LVNLEKDLVQQKD 848
>EP15R_MOUSE (Q60902) Epidermal growth factor receptor substrate 15-like 1| (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs) Length = 907 Score = 37.7 bits (86), Expect = 0.030 Identities = 43/160 (26%), Positives = 75/160 (46%), Gaps = 20/160 (12%) Frame = +3 Query: 150 LREQTNEIASFRRE---LDNSEAERAQHLKQ----IHDLQEHLREKESQYLALEEQHRVA 308 L + + EIA +RE L+ E+ + +KQ + +LQ L + S LE Q + A Sbjct: 384 LDDISQEIAQLQREKYSLEQDIREKEEAIKQKTSEVQELQNDLDRETSSLQELEAQKQDA 443 Query: 309 QDNILYKDEQ---LRDAHAWITR-----VQEMDIL--QSQSLQAELRERTDQFGQCWA-- 452 QD + D+Q LRD + + + Q + L Q QS +++L+ + D + + Sbjct: 444 QDRLDEMDQQKAKLRDMLSDVRQKCQDETQTISSLKTQIQSQESDLKSQEDDLNRAKSEL 503 Query: 453 -TFQQQYVEMQQGFLHTIQRLQLELIELRDRTGEQDVSQA 569 QQ+ +++Q R QLE I + + D++QA Sbjct: 504 NRLQQEETQLEQSI--QAGRAQLETILRSLKCTQDDINQA 541
>YQ91_CAEEL (Q10030) Hypothetical protein C27D6.1| Length = 782 Score = 37.7 bits (86), Expect = 0.030 Identities = 34/132 (25%), Positives = 66/132 (50%), Gaps = 1/132 (0%) Frame = +3 Query: 15 AEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRREL 194 AEK K++ K + ELE++L +T + + ++ Q + L E+ NE+ E+ Sbjct: 256 AEKWKDRATRNSKRLPELELELAETVQAKEEWQVKSQEMEIQNKQLVEELNEVQKKLEEI 315 Query: 195 DNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNI-LYKDEQLRDAHAWITRV 371 +NS ++ H K + L +L E+ Q E+ ++Q N+ + + E ++ I+ Sbjct: 316 ENS--QKTFHQKVVSTL--NLDEEYFQNPDEEQDGSLSQFNMDVLEQEIVKYQEKCISLK 371 Query: 372 QEMDILQSQSLQ 407 QE +IL+ + Q Sbjct: 372 QENEILKEKLQQ 383
>ROCK1_MOUSE (P70335) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) Length = 1354 Score = 37.7 bits (86), Expect = 0.030 Identities = 46/191 (24%), Positives = 86/191 (45%), Gaps = 5/191 (2%) Frame = +3 Query: 21 KLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDN 200 KL+EQLH + E+E K ++ +LD + ++ +E + RR L++ Sbjct: 434 KLEEQLHNEMQLKDEMEQKCRTSNLKLDK--------------IMKELDEEGNQRRNLES 479 Query: 201 --SEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQ 374 S+ E+ + L Q H + E+ R+ E + E+ R ++ + +QL D ++ Sbjct: 480 AVSQIEKEKMLLQ-HRINEYQRKVEQE----NEKRRNIENEVSTLKDQLEDLRK-ASQTS 533 Query: 375 EMDILQSQSLQAELRERTDQF---GQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDRT 545 ++ + LQ +L E D ++ + EM + + ++ L EL E R+R Sbjct: 534 QLANEKLTQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKS-ISQLESLNRELQE-RNRI 591 Query: 546 GEQDVSQAAQD 578 E SQA +D Sbjct: 592 LENSKSQADKD 602
>PCNT_MOUSE (P48725) Pericentrin| Length = 1920 Score = 37.7 bits (86), Expect = 0.030 Identities = 43/161 (26%), Positives = 70/161 (43%), Gaps = 26/161 (16%) Frame = +3 Query: 18 EKLKEQLHEREKYILELE---MKLNDTHRELDTLKIDHQAVWANQDLLREQTNE-IASFR 185 E L ++ ++ ILELE +L REL TLK + +W ++ L + E A+ + Sbjct: 1124 EALGKKEESEQQLILELEDLRKQLEQAARELLTLKEEKSVLWNQKETLTNEAKEREAALQ 1183 Query: 186 RELDN-----------SEAERAQHLKQIHDLQEHLREKESQY---------LALEEQHRV 305 E+++ SE +RA L Q+ L+ L ++ Q+ +A +Q Sbjct: 1184 EEVESLTRVQWESRKQSEKDRATLLSQMRVLESELEDQLVQHRGCAQLAEEVATLKQQLA 1243 Query: 306 AQDNILYKDEQLRDAHAWITRVQEMDILQS--QSLQAELRE 422 A D L Q D A R E + Q Q L+ +LR+ Sbjct: 1244 ALDKHLRSQRQFMDDQA-AERDDEREEFQQEIQRLEGQLRQ 1283 Score = 32.0 bits (71), Expect = 1.6 Identities = 52/226 (23%), Positives = 98/226 (43%), Gaps = 29/226 (12%) Frame = +3 Query: 18 EKLKEQLH-EREKYILELEMKLNDTHR-ELDTLKIDHQAVWANQDLLREQTNEIASFRRE 191 E LK+ ERE + L +L+ H+ E++ L+ Q + Q + E+ + A E Sbjct: 217 ETLKQDWESERELCLENLRQELSLKHQSEMEGLQSQFQKELSEQKVELEKIFQ-AKHEAE 275 Query: 192 LDNSEAERAQHLKQIHDLQEHLREKESQYLA-LEEQHRVAQDNILYKDEQLRDAHAWITR 368 + E AQH I LQE L+ + QYL LE++ R + + E L+ ++ + Sbjct: 276 VSLKNLE-AQHQAAIKKLQEDLQSEHCQYLQDLEQKFREKEKAKELELETLQASYEDLKA 334 Query: 369 VQEMDILQSQSLQAELRERTDQFGQCW------ATFQQQYVEMQQGFLHTIQ----RLQL 518 + +I S ++ ++ W A+ ++ ++ GF Q + + Sbjct: 335 QSQEEIRLLWSQLESMKTNREELNGSWDPVLAQASHLEELEHLRSGFAQQQQQERAQHES 394 Query: 519 ELIELR----------DRTGEQDVS------QAAQDGSAESSYVQS 608 EL LR ++T ++D++ Q A++ S ES+ + S Sbjct: 395 ELEHLRVYFEKKLKDAEKTYQEDLTVFQQRLQEAREDSLESTEISS 440
>HMMR_MOUSE (Q00547) Hyaluronan mediated motility receptor (Intracellular| hyaluronic acid-binding protein) (Receptor for hyaluronan-mediated motility) Length = 794 Score = 37.7 bits (86), Expect = 0.030 Identities = 48/198 (24%), Positives = 95/198 (47%), Gaps = 8/198 (4%) Frame = +3 Query: 9 VAAEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRR 188 + EK+ E+ E EK +LE +++ +++ K+D + ++ L+E+ EI S ++ Sbjct: 220 IEKEKIDEKC-ETEK-LLEYIQEISCASDQVEKCKVDIAQL---EEDLKEKDREILSLKQ 274 Query: 189 ELDNSEAERAQHLKQIHDLQE--HLREKESQYLALEEQHRV----AQDNILYKDEQLRDA 350 L+ E KQI DL L E E L +++ R A+ IL E+L Sbjct: 275 SLE----ENITFSKQIEDLTVKCQLLETERDNLVSKDRERAETLSAEMQIL--TERLALE 328 Query: 351 HAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQ--RLQLEL 524 ++Q+ + LQSQSL + +E + + Q +FQ++ + F ++ +L+ Sbjct: 329 RQEYEKLQQKE-LQSQSLLQQEKELSARLQQQLCSFQEEMTSEKNVFKEELKLALAELDA 387 Query: 525 IELRDRTGEQDVSQAAQD 578 ++ ++ E+ V Q ++ Sbjct: 388 VQQKEEQSERLVKQLEEE 405 Score = 32.0 bits (71), Expect = 1.6 Identities = 37/146 (25%), Positives = 69/146 (47%), Gaps = 15/146 (10%) Frame = +3 Query: 15 AEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLL-REQTNEIASFRRE 191 +E+L +QL E K E +L++ RE + H A A L+ +E+ N+ A R+ Sbjct: 395 SERLVKQLEEERKSTAEQLTRLDNLLREKEVELEKHIAAHAQAILIAQEKYNDTAQSLRD 454 Query: 192 LDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQH------------RVAQDNILYKD- 332 + ++ E Q ++ +D + LR+ +Q + +E++ ++ + Y D Sbjct: 455 V-TAQLESVQ--EKYNDTAQSLRDVTAQLESEQEKYNDTAQSLRDVTAQLESEQEKYNDT 511 Query: 333 -EQLRDAHAWITRVQEMDILQSQSLQ 407 + LRD A + VQE +QSL+ Sbjct: 512 AQSLRDVTAQLESVQEKYNDTAQSLR 537
>SOJO_XENLA (Q9PW73) Cytoskeletal protein Sojo (p170)| Length = 1335 Score = 37.4 bits (85), Expect = 0.039 Identities = 51/215 (23%), Positives = 88/215 (40%), Gaps = 15/215 (6%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKI-DHQAVWANQDL-------------LR 155 ++ KE + + E L+LEMK + T+ I + +W Q L L Sbjct: 591 DQQKELMKQIEHLQLQLEMKNLHAGEQKHTITILQQETLWHEQQLESVNHLLTQARKELE 650 Query: 156 EQTNEIASFRRELDNSEAERAQHLKQIHDLQEHLREKESQYL-ALEEQHRVAQDNILYKD 332 QT ++ + L N + + Q+ +E+ + YL LE+ ++ I K Sbjct: 651 IQTKNTSAAMKSLQNQVEVESAKVSQLESALTVCKEELALYLHELEDNREQFENQIKTKS 710 Query: 333 EQLRDAHAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRL 512 E+L W +Q L++QSLQ E +++ + T QQQ +QQG I L Sbjct: 711 EEL-----WC--LQNEIKLRTQSLQ----ETSEENVRLQQTLQQQQHMLQQG-TGRIGEL 758 Query: 513 QLELIELRDRTGEQDVSQAAQDGSAESSYVQSKGS 617 + EL + + + Q +E ++K S Sbjct: 759 EDHHTELEKQVSKLEFELEKQRSMSEDMLQRTKDS 793
>LCD1_ASHGO (Q751Y8) DNA damage checkpoint protein LCD1| Length = 694 Score = 37.4 bits (85), Expect = 0.039 Identities = 24/80 (30%), Positives = 40/80 (50%), Gaps = 7/80 (8%) Frame = +3 Query: 87 THRELDTLKIDHQAVWANQDLLRE-----QTNEIASFRRELDNSEAERAQHLKQIHDLQE 251 TH +LD L++D +LR+ Q + R L + + +HL+++ LQE Sbjct: 49 THEDLDKLQMDLMTARGESGMLRDRLMMLQQEKDRERERLLGREQELQGRHLQELQKLQE 108 Query: 252 HLR--EKESQYLALEEQHRV 305 L+ E E Q+L LE++ V Sbjct: 109 ELQRLEDEKQFLVLEKRQLV 128
>TRHY_SHEEP (P22793) Trichohyalin| Length = 1549 Score = 37.4 bits (85), Expect = 0.039 Identities = 50/196 (25%), Positives = 88/196 (44%), Gaps = 13/196 (6%) Frame = +3 Query: 27 KEQLHEREKYILELEMKLN-------DTHRELDTLKIDHQAVWANQDLLREQTNEIASFR 185 +E+L +R K ELE LN RE L+++ Q + LRE+ E+ + Sbjct: 168 EEELQQRPKG-RELEELLNREQRFERQEQRERQRLQVEQQQRQRGE--LRERQEEVQLQK 224 Query: 186 RELDNSEAER----AQHLKQIHDLQEHLREKE--SQYLALEEQHRVAQDNILYKDEQLRD 347 RE + ER Q KQ L+E L E+E Q L +EQ R +++QLR Sbjct: 225 RETQELQRERLEEEQQLQKQKRGLEERLLEQERREQELRRKEQER--------REQQLRQ 276 Query: 348 AHAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELI 527 T+ + + +S++ + + + ++ + + + + + QQ +R + EL+ Sbjct: 277 EQEEATQEEISERGESRTSRCQWQLESEADARQRKVYSRPHRQEQQS-----RRQEQELL 331 Query: 528 ELRDRTGEQDVSQAAQ 575 E R EQ +S+ Q Sbjct: 332 E---RQQEQQISEEVQ 344 Score = 35.0 bits (79), Expect = 0.19 Identities = 43/204 (21%), Positives = 89/204 (43%), Gaps = 20/204 (9%) Frame = +3 Query: 27 KEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFR------- 185 KEQ +RE+ +L E + ++D + + + D + NE+ + R Sbjct: 815 KEQQLQREECEKRRRQELERQLEEEELQRLDRKRQFRDDD---QHQNEVRNSRVYSKHRE 871 Query: 186 -----RELDNS---EAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQL 341 R+LD+S E++ Q L+ + D QE RE+E ++ + +++ L + EQ Sbjct: 872 NKEKSRQLDDSWVRESQFQQDLRPLQDEQEEKREREQEWRSRQKRDSQFPAEQLLEREQQ 931 Query: 342 RDAHAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRL--- 512 ++ + +E + Q L+ + E+ +Y+E + F Q+L Sbjct: 932 KETERRDRKFRE----EEQLLKGQREEKI------------RYLEEDRKFREEEQQLRRL 975 Query: 513 --QLELIELRDRTGEQDVSQAAQD 578 + +L + RDR +++S+ +D Sbjct: 976 EREQQLRQERDRKFREELSRQERD 999 Score = 35.0 bits (79), Expect = 0.19 Identities = 31/142 (21%), Positives = 72/142 (50%) Frame = +3 Query: 9 VAAEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRR 188 V ++ +++ ERE+ LE E++ R+ + L+ + Q + ++ R++ R+ Sbjct: 632 VQRQEREKRRQERERQYLEKELQ-----RQEERLQEEEQLLREEREKRRQERE-----RQ 681 Query: 189 ELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITR 368 L+ E + + L++ + ++ +E+E QYL EE R ++ + + EQL+ R Sbjct: 682 YLEKVELQEEEQLQR-EEREKRRQERERQYLEKEELQR-QEERLQREKEQLQRE----DR 735 Query: 369 VQEMDILQSQSLQAELRERTDQ 434 + + + + L+ EL++ D+ Sbjct: 736 EKRRQVRERKYLEEELQQEEDR 757 Score = 33.9 bits (76), Expect = 0.43 Identities = 37/178 (20%), Positives = 80/178 (44%) Frame = +3 Query: 21 KLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDN 200 +LKE+ +REK E E + +RE++ + + + + L RE+ + RE Sbjct: 397 RLKEEKLQREKRRQERERQ----YREVELQREEERLQREEEQLQREEREKRRRQEREKQY 452 Query: 201 SEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQEM 380 E +Q+ + R +E + LE+ ++ + ++ + R ++++ Sbjct: 453 LEKVELWEEEQLQREEREKRRQEREKQYLEKVELREEEQLQRQEREKRRQERERQYLEKV 512 Query: 381 DILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDRTGEQ 554 ++ + + LQ E RE+ Q ++QY+E + L ++LQ + E R + E+ Sbjct: 513 ELQEEEQLQREEREKRRQ------ERERQYLEKVE--LQEEEQLQRQEREKRRQEREK 562 Score = 31.6 bits (70), Expect = 2.1 Identities = 41/175 (23%), Positives = 74/175 (42%), Gaps = 14/175 (8%) Frame = +3 Query: 33 QLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRE---LDNS 203 + E E+ + E E +L R+ + + Q + ++ LR Q + FR E L S Sbjct: 1276 KFREEEQLLQEREEQLRRQERDRK-FREEEQLLQEREEQLRRQERD-RKFREEEQLLKES 1333 Query: 204 EAE--RAQHLKQIHDLQEHLREKESQYL---------ALEEQHRVAQDNILYKDEQLRDA 350 E + R + ++ H+ + LRE+E Q L + EEQ R A+ + ++ RD Sbjct: 1334 EEQLRRQERDRKFHEKEHLLREREEQQLRRQELEGVFSQEEQLRRAEQEEEQRRQRQRD- 1392 Query: 351 HAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQ 515 + + QSLQ E E + + F +Q ++ + ++R Q Sbjct: 1393 --------RKFLEEEQSLQREREEEKRRVQEQDRKFLEQEEQLHREEQEELRRRQ 1439 Score = 30.4 bits (67), Expect = 4.8 Identities = 33/137 (24%), Positives = 63/137 (45%), Gaps = 1/137 (0%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELD 197 E+L+ + E+ + + E + + +E D L+ + Q LLRE + R+ L+ Sbjct: 728 EQLQREDREKRRQVRERKYLEEELQQEEDRLQREKQ-------LLREDREK----RQYLE 776 Query: 198 NSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQE 377 E +R + LQ R +E + EE+ ++ + K++QL+ R QE Sbjct: 777 KVELQREEE-----QLQREKRRQERERQYREEELLREEERLHRKEQQLQREECEKRRRQE 831 Query: 378 MD-ILQSQSLQAELRER 425 ++ L+ + LQ R+R Sbjct: 832 LERQLEEEELQRLDRKR 848
>EP15_MOUSE (P42567) Epidermal growth factor receptor substrate 15 (Protein| Eps15) (AF-1p protein) Length = 897 Score = 37.4 bits (85), Expect = 0.039 Identities = 39/178 (21%), Positives = 82/178 (46%), Gaps = 5/178 (2%) Frame = +3 Query: 93 RELDTLKIDHQAVWANQDLLREQTNEIASFRRELDNSEAERAQHLKQIHDLQEHLREKES 272 +ELDTL +++ V DL RE+ N ++L E Q ++ DLQ+ ++ + Sbjct: 333 KELDTL--NNEIV----DLQREKNN----VEQDLKEKEDTVKQRTSEVQDLQDEVQRESI 382 Query: 273 QYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQEMDILQSQSLQAELRERTDQFGQCWA 452 L+ Q + Q+ + DEQ + V++ ++Q + + E T Q Q + Sbjct: 383 NLQKLQAQKQQVQELLGELDEQKAQLEEQLQEVRKKCAEEAQLISSLKAEITSQESQI-S 441 Query: 453 TFQQQYVEMQQGFLHTIQRLQLELIELRD-----RTGEQDVSQAAQDGSAESSYVQSK 611 +++++ ++ ++ + RLQ E +L + + + + Q Q+ E S +Q + Sbjct: 442 SYEEELLKARE----ELSRLQQETAQLEESVESGKAQLEPLQQHLQESQQEISSMQMR 495
>MYH9_HUMAN (P35579) Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle| myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A) Length = 1959 Score = 37.4 bits (85), Expect = 0.039 Identities = 30/147 (20%), Positives = 72/147 (48%), Gaps = 4/147 (2%) Frame = +3 Query: 6 VVAAEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTN---EIA 176 ++ + +E++ +E+ ++++ K L ++ + A + L+EQ E+ Sbjct: 836 LLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELC 895 Query: 177 SFRRELDNSEAERAQHLKQI-HDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAH 353 + EL + Q L++I HDL+ + E+E + L+ + + Q NI +EQL + Sbjct: 896 AEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEE 955 Query: 354 AWITRVQEMDILQSQSLQAELRERTDQ 434 + ++Q L+ + +A+L++ ++ Sbjct: 956 SARQKLQ----LEKVTTEAKLKKLEEE 978 Score = 35.0 bits (79), Expect = 0.19 Identities = 46/185 (24%), Positives = 75/185 (40%), Gaps = 11/185 (5%) Frame = +3 Query: 3 HVVAAEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWAN-QDLLREQTNEIAS 179 H L+E+L EK ELE T R+L+ D A Q + E ++A Sbjct: 1024 HEAMITDLEERLRREEKQRQELEK----TRRKLEGDSTDLSDQIAELQAQIAELKMQLAK 1079 Query: 180 FRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAW 359 EL + A + Q + + +RE ESQ L+E + + ++Q RD Sbjct: 1080 KEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEE 1139 Query: 360 I--TRVQEMDILQSQSLQAELRERTDQ--------FGQCWATFQQQYVEMQQGFLHTIQR 509 + + + D L S + Q ELR + +Q + T + Q EM+Q ++ Sbjct: 1140 LEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEE 1199 Query: 510 LQLEL 524 L +L Sbjct: 1200 LAEQL 1204 Score = 30.0 bits (66), Expect = 6.2 Identities = 28/111 (25%), Positives = 51/111 (45%) Frame = +3 Query: 3 HVVAAEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASF 182 H E ++QL + K EL++KL + T+K ++A + +IA Sbjct: 1771 HAQKNENARQQLERQNK---ELKVKLQEME---GTVKSKYKAS------ITALEAKIAQL 1818 Query: 183 RRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDE 335 +LDN ER KQ+ ++ L++ L ++++ R A+ YKD+ Sbjct: 1819 EEQLDNETKERQAACKQVRRTEKKLKD---VLLQVDDERRNAEQ---YKDQ 1863
>ROCK1_PANTR (P61584) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (Fragment) Length = 1003 Score = 37.0 bits (84), Expect = 0.051 Identities = 45/191 (23%), Positives = 86/191 (45%), Gaps = 5/191 (2%) Frame = +3 Query: 21 KLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDN 200 KL+EQLH + E+E K ++ +LD + ++ +E + RR L++ Sbjct: 83 KLEEQLHNEMQLKDEMEQKCRTSNIKLDK--------------IMKELDEEGNQRRNLES 128 Query: 201 --SEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQ 374 S+ E+ + L Q H + E+ R+ E + E+ R ++ + +QL D +++ Sbjct: 129 TVSQIEKEKMLLQ-HRINEYQRKAEQE----NEKRRNVENEVSTLKDQLEDLKK-VSQNS 182 Query: 375 EMDILQSQSLQAELRERTDQF---GQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDRT 545 ++ + LQ +L E D ++ + EM + + ++ L EL E R+R Sbjct: 183 QLANEKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKS-ISQLESLNRELQE-RNRI 240 Query: 546 GEQDVSQAAQD 578 E SQ +D Sbjct: 241 LENSKSQTDKD 251
>ROCK1_RAT (Q63644) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (p150 RhoA-binding kinase ROK beta) (Liver regeneration-related protein LRRG199) Length = 1369 Score = 37.0 bits (84), Expect = 0.051 Identities = 40/181 (22%), Positives = 83/181 (45%), Gaps = 27/181 (14%) Frame = +3 Query: 21 KLKEQLHEREKYILELEMKLNDTHRELDTL--KIDHQA------------VWANQDLLRE 158 KL+EQLH + E+E K ++ +LD + ++D + + + LL+ Sbjct: 434 KLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLESAVSQIEKEKMLLQH 493 Query: 159 QTNEIASFRRELDNSEAERAQHLKQIHDLQEHLRE----KESQYLALEE----QHRVAQD 314 + NE ++R+++ +R ++ L++ L + +S LA E+ Q ++ + Sbjct: 494 RINE---YQRKVEQENEKRRNVENEVSTLKDQLEDLRKASQSSQLANEKLTQLQKQLEEA 550 Query: 315 NILYKDE-----QLRDAHAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEM 479 N L + E +LR +H +++ + Q +SL EL+ER + + Y ++ Sbjct: 551 NDLLRTESDTAVRLRKSHTEMSK----SVSQLESLNRELQERNRMLENSKSQADKDYYQL 606 Query: 480 Q 482 Q Sbjct: 607 Q 607
>ATG11_PICAN (Q67C55) Autophagy-related protein 11 (Peroxisome degradation| deficient protein 18) Length = 1299 Score = 37.0 bits (84), Expect = 0.051 Identities = 27/106 (25%), Positives = 60/106 (56%), Gaps = 1/106 (0%) Frame = +3 Query: 168 EIASFRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRD 347 EI ++ D +E +R + K+I DLQ+ EK+ + ALEE+++ N+ +E+L + Sbjct: 839 EIEELKKGTDLAELDRLK--KEIEDLQKADMEKDKRLAALEEENK----NLKESNEELTN 892 Query: 348 AHAWITRV-QEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQ 482 ++ + + +E+ ++S L+ + ++ +FG+ QQ+ E++ Sbjct: 893 SNKELVNMCEELKSMKSDLLE-NMTQKESEFGKEAKVNQQEINELK 937
>MYSP_TAESA (Q8T305) Paramyosin| Length = 863 Score = 37.0 bits (84), Expect = 0.051 Identities = 45/210 (21%), Positives = 83/210 (39%), Gaps = 38/210 (18%) Frame = +3 Query: 9 VAAE--KLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQ----TNE 170 +AAE +L ++ + E EL+ ++++ E++TL + A+ A+ L+ Q T+ Sbjct: 347 LAAENGELTHRVKQAENLANELQRRIDEMTVEINTLNSANSALEADNMRLKGQVGDLTDR 406 Query: 171 IASFRRE----------------------------LDNSEAERAQHLKQIHDLQEHLREK 266 IA+ RE EAER +HD +E L+E Sbjct: 407 IANLDRENRQLGDQLKETKSALRDANRRLTDLEALRSQLEAERDNLASALHDAEEALKEM 466 Query: 267 ESQYL----ALEEQHRVAQDNILYKDEQLRDAHAWITRVQEMDILQSQSLQAELRERTDQ 434 E++Y+ AL + + KDE+L + TR + E T Sbjct: 467 EAKYVASQNALNHLKSEMEQRLREKDEELENLRKSTTRT--------------IEELTTT 512 Query: 435 FGQCWATFQQQYVEMQQGFLHTIQRLQLEL 524 + F+ +++ + TI L+++L Sbjct: 513 ISEMEVRFKSDMSRLKKKYEATISELEVQL 542
>MY18A_MOUSE (Q9JMH9) Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain)| (Molecule associated with JAK3 N-terminus) (MAJN) Length = 2035 Score = 37.0 bits (84), Expect = 0.051 Identities = 29/128 (22%), Positives = 58/128 (45%), Gaps = 19/128 (14%) Frame = +3 Query: 21 KLKEQLHERE-------KYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIAS 179 +LK QL E E K +E+++ D H ++D + A+ L+ + NEI + Sbjct: 1683 QLKNQLEESEFTCAAAVKARKAMEVEMEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQN 1742 Query: 180 FRRELDNSE------------AERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNIL 323 R E D + A+ ++ + Q++DLQ + E + L+E+ + Q + Sbjct: 1743 -RLEEDQEDMNELMKKHKAAVAQASRDMAQMNDLQAQIEESNKEKQELQEKLQALQSQVE 1801 Query: 324 YKDEQLRD 347 + ++ + D Sbjct: 1802 FLEQSMVD 1809 Score = 37.0 bits (84), Expect = 0.051 Identities = 42/205 (20%), Positives = 89/205 (43%), Gaps = 32/205 (15%) Frame = +3 Query: 39 HEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQ------------------T 164 HE EK + +L+ H E K+ + + +D+L + T Sbjct: 1450 HELEKKQRRFDSELSQAHEETQREKLQREKLQREKDMLLAEAFSLKQQMEEKDLDIAGFT 1509 Query: 165 NEIASFRRELDN-------SEAERAQHLKQIHDLQEHLREKESQYLALEEQH------RV 305 ++ S EL + EA A+ KQ+ DL+ ++++E + L+EQ Sbjct: 1510 QKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEE---LDEQAGSIQMLEQ 1566 Query: 306 AQDNILYKDEQLRDAHAWITRVQEMDILQS-QSLQAELRERTDQFGQCWATFQQQYVEMQ 482 A+ + + E++R H+ ++ ++ ++ QS Q +L++ Q +++Y + Q Sbjct: 1567 AKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQ-------LEEEYEDKQ 1619 Query: 483 QGFLHTIQRLQLELIELRDRTGEQD 557 + L + L+ +L L D+ ++D Sbjct: 1620 KA-LREKRELESKLSTLSDQVNQRD 1643 Score = 33.1 bits (74), Expect = 0.73 Identities = 34/147 (23%), Positives = 68/147 (46%), Gaps = 6/147 (4%) Frame = +3 Query: 12 AAEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRE 191 A L+EQL ++ E++ +L + +++ L H+A A Q N++ Sbjct: 1722 AKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDMAQMNDL------ 1775 Query: 192 LDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWI--- 362 +A+ + K+ +LQE L+ +SQ L EQ V + + ++ ++R+ + Sbjct: 1776 ----QAQIEESNKEKQELQEKLQALQSQVEFL-EQSMVDKSLVSRQEAKIRELETRLEFE 1830 Query: 363 -TRVQEMDILQS--QSLQAELRERTDQ 434 T+V+ ++ L S + +L E DQ Sbjct: 1831 KTQVKRLENLASRLKETMEKLTEERDQ 1857
>ROCK1_HUMAN (Q13464) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen) Length = 1354 Score = 37.0 bits (84), Expect = 0.051 Identities = 45/191 (23%), Positives = 86/191 (45%), Gaps = 5/191 (2%) Frame = +3 Query: 21 KLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDN 200 KL+EQLH + E+E K ++ +LD + ++ +E + RR L++ Sbjct: 434 KLEEQLHNEMQLKDEMEQKCRTSNIKLDK--------------IMKELDEEGNQRRNLES 479 Query: 201 --SEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQ 374 S+ E+ + L Q H + E+ R+ E + E+ R ++ + +QL D +++ Sbjct: 480 TVSQIEKEKMLLQ-HRINEYQRKAEQE----NEKRRNVENEVSTLKDQLEDLKK-VSQNS 533 Query: 375 EMDILQSQSLQAELRERTDQF---GQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDRT 545 ++ + LQ +L E D ++ + EM + + ++ L EL E R+R Sbjct: 534 QLANEKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKS-ISQLESLNRELQE-RNRI 591 Query: 546 GEQDVSQAAQD 578 E SQ +D Sbjct: 592 LENSKSQTDKD 602
>PSPA_SHIFL (P0AFM8) Phage shock protein A| Length = 221 Score = 37.0 bits (84), Expect = 0.051 Identities = 24/73 (32%), Positives = 34/73 (46%), Gaps = 8/73 (10%) Frame = +3 Query: 30 EQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLR--------EQTNEIASFR 185 + L +K I ELE KL++T L + HQA +++D+ R E SF Sbjct: 112 DTLARMKKEIGELENKLSETRARQQALMLRHQAANSSRDVRRQLDSGKLDEAMARFESFE 171 Query: 186 RELDNSEAERAQH 224 R +D EAE H Sbjct: 172 RRIDQMEAEAESH 184
>PSPA_ECOLI (P0AFM6) Phage shock protein A| Length = 221 Score = 37.0 bits (84), Expect = 0.051 Identities = 24/73 (32%), Positives = 34/73 (46%), Gaps = 8/73 (10%) Frame = +3 Query: 30 EQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLR--------EQTNEIASFR 185 + L +K I ELE KL++T L + HQA +++D+ R E SF Sbjct: 112 DTLARMKKEIGELENKLSETRARQQALMLRHQAANSSRDVRRQLDSGKLDEAMARFESFE 171 Query: 186 RELDNSEAERAQH 224 R +D EAE H Sbjct: 172 RRIDQMEAEAESH 184
>PSPA_ECO57 (P0AFM7) Phage shock protein A| Length = 221 Score = 37.0 bits (84), Expect = 0.051 Identities = 24/73 (32%), Positives = 34/73 (46%), Gaps = 8/73 (10%) Frame = +3 Query: 30 EQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLR--------EQTNEIASFR 185 + L +K I ELE KL++T L + HQA +++D+ R E SF Sbjct: 112 DTLARMKKEIGELENKLSETRARQQALMLRHQAANSSRDVRRQLDSGKLDEAMARFESFE 171 Query: 186 RELDNSEAERAQH 224 R +D EAE H Sbjct: 172 RRIDQMEAEAESH 184
>HOOK1_MOUSE (Q8BIL5) Hook homolog 1| Length = 728 Score = 37.0 bits (84), Expect = 0.051 Identities = 35/170 (20%), Positives = 84/170 (49%), Gaps = 35/170 (20%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEM-------KLNDTHRELDTLKID----------------HQA 128 E+L+EQL ++ + + ELE ++ + ++++ L+ Q Sbjct: 490 EQLQEQLEQKHRKMNELETEQRLSKERIGELQQQIEDLQKSLQEQGSKSEGESSSKLKQK 549 Query: 129 VWANQDLLREQTNEIASFRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRV- 305 + A+ + L E E+ + +++ + + +Q+ ++I +L+ L++K+ A+EE++++ Sbjct: 550 LEAHMEKLTEVHEELQKKQELIEDLQPDISQNAQKISELEAALQKKDEDMKAMEERYKMY 609 Query: 306 ---AQDNILYKDEQLRDAHAWI--------TRVQEMDILQSQSLQAELRE 422 A++ I D +L A A I + + ++IL+S+ A+LR+ Sbjct: 610 LEKARNVIKTLDPKLNPASAEIMLLRKQLAEKERRIEILESECKVAKLRD 659
>TPR_HUMAN (P12270) Nucleoprotein TPR| Length = 2349 Score = 37.0 bits (84), Expect = 0.051 Identities = 46/209 (22%), Positives = 84/209 (40%), Gaps = 35/209 (16%) Frame = +3 Query: 18 EKLKE--------QLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLL------- 152 EKLKE QL E ++ +K + E + + Q W N +L Sbjct: 150 EKLKESNTTKGELQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELL 209 Query: 153 ---REQTNEIASFRRELDNSEAERAQHLKQIHDLQ---EHLREKESQYLALEEQHRVAQD 314 RE+ NEI + L+N + E ++ +Q++ L+ EHL++ L ++ + Q Sbjct: 210 ALGREKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQA 269 Query: 315 NILYKDEQLRDAHAWITRVQEMDILQSQSLQAELRERTDQF-------GQCWATFQQQYV 473 ++ K +AH ++ + + S++ EL ++ G+ Q + Sbjct: 270 SMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEELHKLLKEAGEANKAIQDHLL 329 Query: 474 EMQQG-------FLHTIQRLQLELIELRD 539 E++Q L I RL+ EL D Sbjct: 330 EVEQSKDQMEKEMLEKIGRLEKELENAND 358 Score = 34.3 bits (77), Expect = 0.33 Identities = 51/231 (22%), Positives = 95/231 (41%), Gaps = 52/231 (22%) Frame = +3 Query: 18 EKLKEQLH----EREKYILELEMKLNDTHRELDTL----------KIDHQAVWANQDLLR 155 + LKE L+ E+E +L+ K+ D ++ T+ K ++ + A QD + Sbjct: 1397 QSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVM 1456 Query: 156 EQT--------------NEIASFRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEE 293 E + E+ + L+ +E + Q+ +LQ+ L EKE++ L+E Sbjct: 1457 ETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQE 1516 Query: 294 Q--------HRVAQD-------------NILYKDEQLRDA-HAWITRVQEMDILQSQSLQ 407 Q R+ QD I K+E+ R A A +++ + ++ Q + Sbjct: 1517 QTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTK 1576 Query: 408 --AELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDRTGEQ 554 EL++R Q + ++ + I RL+ EL E ++R EQ Sbjct: 1577 ENEELKQRNGALDQQKDELDVRITALKSQYEGRISRLERELREHQERHLEQ 1627 Score = 29.6 bits (65), Expect = 8.1 Identities = 30/136 (22%), Positives = 64/136 (47%) Frame = +3 Query: 21 KLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDN 200 K +EQ+ E ++I E ++ +T E+ +++ +LL + E+ + N Sbjct: 1191 KSQEQILEILRFIRR-EKEIAETRFEV--AQVESLRYRQRVELLERELQEL----EDSLN 1243 Query: 201 SEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQEM 380 +E E+ Q + E L +K + E +++ ++ ++ L+ A + ++ E+ Sbjct: 1244 AEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKL-EL 1302 Query: 381 DILQSQSLQAELRERT 428 DIL Q AEL E++ Sbjct: 1303 DILPLQEANAELSEKS 1318
>CEP72_HUMAN (Q9P209) Centrosomal protein of 72 kDa (Cep72 protein)| Length = 647 Score = 37.0 bits (84), Expect = 0.051 Identities = 30/138 (21%), Positives = 66/138 (47%) Frame = +3 Query: 21 KLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDN 200 +L EQ + + + E+ +L+ TH+ELD L+ L+ + + S ++E+ + Sbjct: 487 RLAEQQQQHAREMSEVTAELHHTHKELDDLRQHLDKSLEENSRLK---SLLLSMKKEVKS 543 Query: 201 SEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQEM 380 ++ +L QI LQ ++ + + L +QH D I + L+++H+ + E Sbjct: 544 ADTAATLNL-QIAGLQTSVKRLCGEIVEL-KQHLEHYDKIQELTQMLQESHSSLVSTNEH 601 Query: 381 DILQSQSLQAELRERTDQ 434 + + ++A+ R +Q Sbjct: 602 LLQELSQVRAQHRAEVEQ 619
>MACF1_MOUSE (Q9QXZ0) Microtubule-actin crosslinking factor 1 (Actin cross-linking| family 7) Length = 5327 Score = 37.0 bits (84), Expect = 0.051 Identities = 42/201 (20%), Positives = 80/201 (39%), Gaps = 29/201 (14%) Frame = +3 Query: 24 LKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVW--------ANQDLLREQTNEIAS 179 +K+QL+E +++ +E+ + +++ K++HQ ++D++RE E+ Sbjct: 4078 VKDQLNEMKEFKVEVYQQ------QIEMEKLNHQGELMLKKATDETDRDIIREPLTELKH 4131 Query: 180 FRRELDNSEAERAQHLK----QIHDLQEHLREKESQYLALEE---------------QHR 302 L A R L+ + Q L E S EE + Sbjct: 4132 LWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDAQRPISGDPKVIEVE 4191 Query: 303 VAQDNILYKDEQLRDAHAWITRVQEMDILQSQSLQ--AELRERTDQFGQCWATFQQQYVE 476 +A+ ++L D A ++L+S + + LR R + QCW + Q+ E Sbjct: 4192 LAKHHVLKNDVLAHQATVATVNKAGSELLESSAGDDASSLRSRLETMNQCWESVLQKTEE 4251 Query: 477 MQQGFLHTIQRLQLELIELRD 539 +Q T+Q+ Q E+ D Sbjct: 4252 REQQLQSTLQQAQGFHSEIED 4272
>NEB2_RAT (O35274) Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase| 1 regulatory subunit 9B) (Neural tissue-specific F-actin-binding protein II) (p130) (PP1bp134) Length = 817 Score = 36.6 bits (83), Expect = 0.066 Identities = 38/138 (27%), Positives = 62/138 (44%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELD 197 EKL + E + E ++ R+L +L+ + W + EQ+ E R E Sbjct: 665 EKLVHKFKELQIKHAVTEAEIQQLKRKLQSLE-QEKGRWRVEKAQLEQSVEENKERMEKL 723 Query: 198 NSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQE 377 AQ L Q D EHLRE ++QY ALE ++ A+ L KD Q + E Sbjct: 724 EGYWGEAQSLCQAVD--EHLRETQAQYQALERKYSKAKR--LIKDYQQK----------E 769 Query: 378 MDILQSQSLQAELRERTD 431 ++ L+ ++ Q + E ++ Sbjct: 770 IEFLKKETAQRRVLEESE 787
>NEB2_MOUSE (Q6R891) Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase| 1 regulatory subunit 9B) Length = 817 Score = 36.6 bits (83), Expect = 0.066 Identities = 38/138 (27%), Positives = 62/138 (44%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELD 197 EKL + E + E ++ R+L +L+ + W + EQ+ E R E Sbjct: 665 EKLVHKFKELQIKHAVTEAEIQQLKRKLQSLE-QEKGRWRVEKAQLEQSVEENKERMEKL 723 Query: 198 NSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQE 377 AQ L Q D EHLRE ++QY ALE ++ A+ L KD Q + E Sbjct: 724 EGYWGEAQSLCQAVD--EHLRETQAQYQALERKYSKAKR--LIKDYQQK----------E 769 Query: 378 MDILQSQSLQAELRERTD 431 ++ L+ ++ Q + E ++ Sbjct: 770 IEFLKKETAQRRVLEESE 787
>MACF1_HUMAN (Q9UPN3) Microtubule-actin crosslinking factor 1, isoforms 1/2/3/5| (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620) Length = 5430 Score = 36.6 bits (83), Expect = 0.066 Identities = 42/201 (20%), Positives = 80/201 (39%), Gaps = 29/201 (14%) Frame = +3 Query: 24 LKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVW--------ANQDLLREQTNEIAS 179 +K+QL+E +++ +E+ + +++ K++HQ ++D++RE E+ Sbjct: 4191 VKDQLNEMKEFKVEVYQQ------QIEMEKLNHQGELMLKKATDETDRDIIREPLTELKH 4244 Query: 180 FRRELDNSEAERAQHLK----QIHDLQEHLREKESQYLALEE---------------QHR 302 L A R L+ + Q L E S EE + Sbjct: 4245 LWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDAQRPISGDPKVIEVE 4304 Query: 303 VAQDNILYKDEQLRDAHAWITRVQEMDILQSQSLQ--AELRERTDQFGQCWATFQQQYVE 476 +A+ ++L D A ++L+S + + LR R + QCW + Q+ E Sbjct: 4305 LAKHHVLKNDVLAHQATVETVNKAGNELLESSAGDDASSLRSRLEAMNQCWESVLQKTEE 4364 Query: 477 MQQGFLHTIQRLQLELIELRD 539 +Q T+Q+ Q E+ D Sbjct: 4365 REQQLQSTLQQAQGFHSEIED 4385 Score = 33.1 bits (74), Expect = 0.73 Identities = 20/80 (25%), Positives = 42/80 (52%), Gaps = 2/80 (2%) Frame = +3 Query: 87 THRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDNSEAERAQHL--KQIHDLQEHLR 260 T ++L L+ + + QD ++ + A+ ++++ E L +++ L+E L Sbjct: 1578 TQQDLSALQKNQSDLKDLQDDIQNRATSFATVVKDIEGFMEENQTKLSPRELTALREKLH 1637 Query: 261 EKESQYLALEEQHRVAQDNI 320 + + QY AL+E+ RVAQ + Sbjct: 1638 QAKEQYEALQEETRVAQKEL 1657
>CNTRB_HUMAN (Q8N137) Centrobin (LYST-interacting protein 8)| Length = 903 Score = 36.6 bits (83), Expect = 0.066 Identities = 46/189 (24%), Positives = 80/189 (42%), Gaps = 10/189 (5%) Frame = +3 Query: 30 EQLHE-REKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDNSE 206 +Q H+ +E Y E RE + + + QA W Q L +E+ ELD + Sbjct: 364 QQEHQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQSEVRRLEGELDTAR 423 Query: 207 AER---AQHLKQIHDLQEHLREKESQYLALEEQHRV------AQDNILYKDEQLRDAHAW 359 ER + + E R + LA++ + RV AQ++ L + LR+ H Sbjct: 424 RERDALQLEMSLVQARYESQRIQLESELAVQLEQRVTERLAQAQESSLRQAASLREHH-- 481 Query: 360 ITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRD 539 R Q D+ S Q EL + QF A +++ ++ + + + R Q + EL Sbjct: 482 --RKQLQDL--SGQHQQELASQLAQFKVEMAEREERQQQVAEDYELRLAREQARVCEL-- 535 Query: 540 RTGEQDVSQ 566 ++G Q + + Sbjct: 536 QSGNQQLEE 544 Score = 32.7 bits (73), Expect = 0.96 Identities = 51/197 (25%), Positives = 86/197 (43%), Gaps = 12/197 (6%) Frame = +3 Query: 18 EKLKEQLHEREKYILE-----LEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASF 182 E+ +L +RE+ LE L ++L + L+ + A A Q + E+ + Sbjct: 295 EQESARLQQRERETLEEERQALTLRLEAEQQRCCVLQEERDAARAGQ---LSEHRELETL 351 Query: 183 RRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWI 362 R L E ER +Q H L+EH Y AL+E+ + + K++ R+A A Sbjct: 352 RAAL---EEERQTWAQQEHQLKEH-------YQALQEESQAQLER--EKEKSQREAQAAW 399 Query: 363 TRVQEMDILQSQ--SLQAEL---RERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLE-- 521 ++ ++QS+ L+ EL R D + Q +Y E Q+ L + +QLE Sbjct: 400 ETQHQLALVQSEVRRLEGELDTARRERDALQLEMSLVQARY-ESQRIQLESELAVQLEQR 458 Query: 522 LIELRDRTGEQDVSQAA 572 + E + E + QAA Sbjct: 459 VTERLAQAQESSLRQAA 475
>UACA_HUMAN (Q9BZF9) Uveal autoantigen with coiled-coil domains and ankyrin| repeats protein Length = 1416 Score = 36.6 bits (83), Expect = 0.066 Identities = 34/141 (24%), Positives = 58/141 (41%) Frame = +3 Query: 63 ELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDNSEAERAQHLKQIHD 242 E E K T +EL +D L EQT + + E+ ++ E + K+I Sbjct: 993 ECERKFKATEKEL-------------KDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFT 1039 Query: 243 LQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQEMDILQSQSLQAELRE 422 LQ+ LR+K E R ++QL+D T V+ + + L E + Sbjct: 1040 LQKDLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQKYTEVKNV----KEKLVEENAK 1095 Query: 423 RTDQFGQCWATFQQQYVEMQQ 485 +T + Q+Q+V ++Q Sbjct: 1096 QTSEILAVQNLLQKQHVPLEQ 1116 Score = 31.2 bits (69), Expect = 2.8 Identities = 33/175 (18%), Positives = 81/175 (46%), Gaps = 8/175 (4%) Frame = +3 Query: 66 LEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDNSEAERAQHLK--QIH 239 L ++N+ ++L ++ +H+ + +EI +REL+N +A+ AQH+K + Sbjct: 639 LSNEVNEKAKKLVEMEREHE----------KSLSEIRQLKRELENVKAKLAQHVKPEEHE 688 Query: 240 DLQEHLREKESQY------LALEEQHRVAQDNILYKDEQLRDAHAWITRVQEMDILQSQS 401 ++ L +K + L L+ Q + +Y D +L A ++ + Sbjct: 689 QVKSRLEQKSGELGKKITELTLKNQTLQKEIEKVYLDNKLLKEQAHNLTIEMKNHYVPLK 748 Query: 402 LQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDRTGEQDVSQ 566 + ++++ D ++ +++ Q + T ++L++E + L + + +DVS+ Sbjct: 749 VSEDMKKSHDAIID---DLNRKLLDVTQKY--TEKKLEMEKLLLENDSLSKDVSR 798
>MYO5B_RAT (P70569) Myosin-5B (Myosin Vb) (Myosin heavy chain myr 6)| Length = 1846 Score = 36.6 bits (83), Expect = 0.066 Identities = 40/175 (22%), Positives = 73/175 (41%), Gaps = 13/175 (7%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLK-IDHQAVWANQDLLREQTNEIASFRREL 194 +KLK L+ER K + + M+ N TH D+ + +Q AN++ L + E+ R ++ Sbjct: 1208 KKLKNDLNERWKAVADQAMQDNSTHSSPDSYSLLLNQLKLANEE-LEVRKEEVLILRTQI 1266 Query: 195 DNSEAERAQHLKQIHDLQEHLREKES-----QYLALEEQHRVAQDN-------ILYKDEQ 338 N++ R ++ S Q A+E H V Q N L +D + Sbjct: 1267 MNADQRRLSGKNMEPNINARTSWPNSEKHVDQEDAIEAYHGVCQTNSQTEDWGYLNEDGE 1326 Query: 339 LRDAHAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTI 503 L A+ + +V + Q Q+ + E + +++ + QQ F T+ Sbjct: 1327 LGLAYQGLKQVARLLEAQLQAQNLKHEEEVEHLKAQVEAMKEEMDKQQQTFCQTL 1381 Score = 33.9 bits (76), Expect = 0.43 Identities = 38/170 (22%), Positives = 67/170 (39%), Gaps = 41/170 (24%) Frame = +3 Query: 12 AAEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWAN---------QDLLREQT 164 +AE LK E +++L+ K++D ++E TL AV + ++L R Q Sbjct: 914 SAEHLKRLNVGMENKVVQLQRKIDDQNKEFKTLSEQLSAVTSTHAMEVEKLKKELARYQQ 973 Query: 165 N-----------EIASFRRELDNSEAER-----------AQHLKQIHDLQ---------- 248 N E+ S R EL + +ER + K++ DL+ Sbjct: 974 NQEADPSLQLQEEVQSLRTELQKAHSERRVLEDAHNRENGELRKRVADLEHENALLKDEK 1033 Query: 249 EHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQEMDILQSQ 398 EHL + + E ++N+L K E + + V+E L+ + Sbjct: 1034 EHLNHQILRQSKAESSQSSVEENLLIKKELEEERSRYQNLVKEYSQLEQR 1083
>MRCKB_RAT (Q7TT49) Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1)| (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta) Length = 1713 Score = 36.6 bits (83), Expect = 0.066 Identities = 33/142 (23%), Positives = 63/142 (44%), Gaps = 29/142 (20%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDT---------------------HRELDTLKIDHQAVW 134 + +++ + + EK ELE +L D REL+TLK+ Sbjct: 613 DSMRQDIRKSEKSRKELEARLEDAVAEASKERKLREHSESFSKQMERELETLKVKQGGRG 672 Query: 135 ANQDLLREQTNEIASFRRELDNS----EAE----RAQHLKQIHDLQEHLREKESQYLALE 290 L +Q EI+ R EL+ E E A H+ ++ ++++ + E ES LAL+ Sbjct: 673 PGATLEHQQ--EISKIRSELEKKVLFYEEELVRREASHVLEVKNVKKEVHESESHQLALQ 730 Query: 291 EQHRVAQDNILYKDEQLRDAHA 356 ++ + +D + ++ R+ H+ Sbjct: 731 KEVLMLKDKL---EKSKRERHS 749
>GOGA3_MOUSE (P55937) Golgin subfamily A member 3 (Golgin-160) (Male-enhanced| antigen 2) (MEA-2) Length = 1487 Score = 36.6 bits (83), Expect = 0.066 Identities = 53/192 (27%), Positives = 77/192 (40%), Gaps = 3/192 (1%) Frame = +3 Query: 24 LKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDNS 203 L +L + ++ + K + E+DTLK Q+ W DL R T+ + Sbjct: 441 LSTRLQAQVEHSHSSQQKQDSLSSEVDTLK---QSCW---DLGRAMTDLQSML------- 487 Query: 204 EAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQEMD 383 EA+ A +DLQ E QY L + Q NIL KD + D Q+M Sbjct: 488 EAKNASLASSNNDLQV----AEEQYQRLMAKVEDMQRNILSKDNTVHDLR------QQMT 537 Query: 384 ILQSQSLQAELRERTDQFGQCWATFQQQYVEMQ---QGFLHTIQRLQLELIELRDRTGEQ 554 LQSQ Q +L ERT + A+ Q + +Q Q + + Q + L+ Sbjct: 538 ALQSQLQQVQL-ERTTLTSKLQAS-QAEITSLQHARQWYQQQLTLAQEARVRLQGEMAHI 595 Query: 555 DVSQAAQDGSAE 590 V Q Q G E Sbjct: 596 QVGQMTQAGLLE 607 Score = 30.0 bits (66), Expect = 6.2 Identities = 30/137 (21%), Positives = 58/137 (42%), Gaps = 1/137 (0%) Frame = +3 Query: 21 KLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDN 200 +LK + + EL +L E T++++H + + L+ +Q E+ + + Sbjct: 864 ELKATKKRLDSEMKELRQELIKLQGEKKTVEVEHSRLQKDMSLVHQQMAELEGHLQSVQK 923 Query: 201 SEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWIT-RVQE 377 E HL + L+ + Q +AL E + + I +E ++A IT + Q+ Sbjct: 924 ERDEMEIHL-------QSLKFDKEQMIALTEANETLKKQI---EELQQEAKKAITEQKQK 973 Query: 378 MDILQSQSLQAELRERT 428 M L S A+ +T Sbjct: 974 MKRLGSDLTSAQKEMKT 990
>NEB2_HUMAN (Q96SB3) Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase| 1 regulatory subunit 9B) Length = 815 Score = 36.6 bits (83), Expect = 0.066 Identities = 38/138 (27%), Positives = 62/138 (44%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELD 197 EKL + E + E ++ R+L +L+ + W + EQ+ E R E Sbjct: 663 EKLVHKFKELQIKHAVTEAEIQQLKRKLQSLE-QEKGRWRVEKAQLEQSVEENKERMEKL 721 Query: 198 NSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQE 377 AQ L Q D EHLRE ++QY ALE ++ A+ L KD Q + E Sbjct: 722 EGYWGEAQSLCQAVD--EHLRETQAQYQALERKYSKAKR--LIKDYQQK----------E 767 Query: 378 MDILQSQSLQAELRERTD 431 ++ L+ ++ Q + E ++ Sbjct: 768 IEFLKKETAQRRVLEESE 785
>ROCK1_RABIT (O77819) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (cAMP-dependent protein kinase ROCK-I) (CePKA) (Corneal epithelial Rho-associated-Ser/Thr kinase 1) (HEB Length = 1354 Score = 36.6 bits (83), Expect = 0.066 Identities = 45/191 (23%), Positives = 86/191 (45%), Gaps = 5/191 (2%) Frame = +3 Query: 21 KLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDN 200 KL+EQLH + E+E K ++ +LD + ++ +E + RR L++ Sbjct: 434 KLEEQLHNEMQLKDEMEQKCRTSNIKLDK--------------IMKELDEEGNQRRNLES 479 Query: 201 --SEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQ 374 S+ E+ + L Q H + E+ R+ E + E+ R ++ + +QL D +++ Sbjct: 480 TVSQIEKEKMLLQ-HRINEYQRKAEQE----NEKRRNVENEVSTLKDQLEDLKK-VSQNS 533 Query: 375 EMDILQSQSLQAELRERTDQF---GQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDRT 545 ++ + LQ +L E D ++ + EM + + ++ L EL E R+R Sbjct: 534 QLANEKLAQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKS-ISQLESLNRELQE-RNRI 591 Query: 546 GEQDVSQAAQD 578 E SQ +D Sbjct: 592 LENSKSQTDKD 602
>GOGA1_HUMAN (Q92805) Golgin subfamily A member 1 (Golgin-97)| Length = 767 Score = 36.6 bits (83), Expect = 0.066 Identities = 47/221 (21%), Positives = 89/221 (40%), Gaps = 32/221 (14%) Frame = +3 Query: 3 HVVAAEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWA----NQDLLREQTNE 170 H +KLKE+ +RE + + L + ++ + + + A + LRE+T Sbjct: 461 HQFELKKLKEEWSQREIVSVAMAQALEEVRKQREEFQQQAANLTAIIDEKEQNLREKTEV 520 Query: 171 IASFRRELDNSEAERAQHLKQIHDLQEHLR--------------EKE----------SQY 278 + +E+ E L QIH LQ L E+E ++ Sbjct: 521 LLQKEQEILQLERGHNSALLQIHQLQAELEALRTLKAEEAAVVAEQEDLLRLRGPLQAEA 580 Query: 279 LALEEQH---RVAQDNILYKDEQLRDAHAWITRVQEMDILQSQSLQAELRERTDQFGQCW 449 L++ E H R QD + R + V MD+ Q Q + +L ++ + + Sbjct: 581 LSVNESHVTSRAMQDPVFQLPTAGRTPNG---EVGAMDLTQLQKEKQDLEQQLLEKNKTI 637 Query: 450 ATFQQQYVEMQQGFLHTIQ-RLQLELIELRDRTGEQDVSQA 569 QQ+ +E+++ ++ R EL E+R++ G + + A Sbjct: 638 KQMQQRMLELRKTLQKELKIRPDNELFEVREKPGPEMANMA 678 Score = 33.9 bits (76), Expect = 0.43 Identities = 35/148 (23%), Positives = 65/148 (43%), Gaps = 12/148 (8%) Frame = +3 Query: 24 LKEQLHEREKYILEL-----EMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRR 188 L QL E + + L EM + ++ + KI H + ++ L + E+ + R Sbjct: 149 LTAQLQEMKNQSMNLFQRRDEMDELEGFQQQELSKIKHMLL-KKEESLGKMEQELEARTR 207 Query: 189 ELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQ--HRV-----AQDNILYKDEQLRD 347 EL ++ E + DL + L E + Y LEEQ H + A+ I +++ ++ Sbjct: 208 ELSRTQEELMNSNQMSSDLSQKLEELQRHYSTLEEQRDHVIASKTGAESKITALEQKEQE 267 Query: 348 AHAWITRVQEMDILQSQSLQAELRERTD 431 A I ++ + Q + AE +E+ D Sbjct: 268 LQALIQQLS----IDLQKVTAETQEKED 291
>MACF4_HUMAN (Q96PK2) Microtubule-actin crosslinking factor 1, isoform 4| Length = 5938 Score = 36.6 bits (83), Expect = 0.066 Identities = 42/201 (20%), Positives = 80/201 (39%), Gaps = 29/201 (14%) Frame = +3 Query: 24 LKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVW--------ANQDLLREQTNEIAS 179 +K+QL+E +++ +E+ + +++ K++HQ ++D++RE E+ Sbjct: 4693 VKDQLNEMKEFKVEVYQQ------QIEMEKLNHQGELMLKKATDETDRDIIREPLTELKH 4746 Query: 180 FRRELDNSEAERAQHLK----QIHDLQEHLREKESQYLALEE---------------QHR 302 L A R L+ + Q L E S EE + Sbjct: 4747 LWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDAQRPISGDPKVIEVE 4806 Query: 303 VAQDNILYKDEQLRDAHAWITRVQEMDILQSQSLQ--AELRERTDQFGQCWATFQQQYVE 476 +A+ ++L D A ++L+S + + LR R + QCW + Q+ E Sbjct: 4807 LAKHHVLKNDVLAHQATVETVNKAGNELLESSAGDDASSLRSRLEAMNQCWESVLQKTEE 4866 Query: 477 MQQGFLHTIQRLQLELIELRD 539 +Q T+Q+ Q E+ D Sbjct: 4867 REQQLQSTLQQAQGFHSEIED 4887 Score = 33.9 bits (76), Expect = 0.43 Identities = 30/124 (24%), Positives = 52/124 (41%), Gaps = 28/124 (22%) Frame = +3 Query: 33 QLHEREKYILELEMKLNDTHRELDTL----------KIDHQAVWANQDL--LREQTNEIA 176 Q E+E + L+ + N H++L+ L HQ QDL L++ +++ Sbjct: 2036 QQMEQEALVKTLQKQQNTCHQQLEDLCSWVGQAERALAGHQGRTTQQDLSALQKNQSDLK 2095 Query: 177 SFRRELDNSEAERAQHLKQIHD----------------LQEHLREKESQYLALEEQHRVA 308 + ++ N A +K I L+E L + + QY AL+E+ RVA Sbjct: 2096 DLQDDIQNRATSFATVVKDIEGFMEENQTKLSPRELTALREKLHQAKEQYEALQEETRVA 2155 Query: 309 QDNI 320 Q + Sbjct: 2156 QKEL 2159
>INVO_PIG (P18175) Involucrin| Length = 347 Score = 36.6 bits (83), Expect = 0.066 Identities = 40/187 (21%), Positives = 80/187 (42%), Gaps = 18/187 (9%) Frame = +3 Query: 9 VAAEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRR 188 V ++ + Q E ++ L +E + ++ L +D Q Q +EQ + ++ Sbjct: 70 VPEQECEPQPQEPQQQELHVEQQQQQQESQVQELHVDQQQ---QQQESQEQELHVDQQQQ 126 Query: 189 ELDNSEAE-----RAQHLKQIHDLQ--EHLREKESQYLALE----EQHRVAQDNILYKDE 335 + ++ E E + Q Q+ +L H +++ESQ L +Q + +Q+ L+ D+ Sbjct: 127 QQESQEQELHVDQQQQQESQVQELHVGHHQQQQESQEQELHVDHHQQQQESQEQELHVDQ 186 Query: 336 QLRDAHAW-----ITRVQEMDILQSQSLQAE--LRERTDQFGQCWATFQQQYVEMQQGFL 494 Q + + + + Q+ Q Q L + +++ Q + QQQ E Q+ L Sbjct: 187 QQQQQESQEQELHVDQQQQQQESQEQELHVDHHQQQQESQVQELHVDHQQQQQESQEQEL 246 Query: 495 HTIQRLQ 515 H Q Q Sbjct: 247 HVDQHQQ 253 Score = 33.5 bits (75), Expect = 0.56 Identities = 33/150 (22%), Positives = 73/150 (48%), Gaps = 13/150 (8%) Frame = +3 Query: 192 LDNSEAERAQHLKQIH-DLQEHLREKESQYLALEEQHRV--AQDNILYKDEQLRDAHAWI 362 ++ + ++ ++++H D Q+ +E + Q L +++Q + +Q+ L+ D+Q + Sbjct: 89 VEQQQQQQESQVQELHVDQQQQQQESQEQELHVDQQQQQQESQEQELHVDQQQQQE---- 144 Query: 363 TRVQEMDI----LQSQSLQAEL------RERTDQFGQCWATFQQQYVEMQQGFLHTIQRL 512 ++VQE+ + Q +S + EL +++ Q + QQQ E Q+ LH Q+ Sbjct: 145 SQVQELHVGHHQQQQESQEQELHVDHHQQQQESQEQELHVDQQQQQQESQEQELHVDQQQ 204 Query: 513 QLELIELRDRTGEQDVSQAAQDGSAESSYV 602 Q + E +++ D Q Q+ + +V Sbjct: 205 QQQ--ESQEQELHVDHHQQQQESQVQELHV 232
>HOOK3_MOUSE (Q8BUK6) Hook homolog 3| Length = 718 Score = 36.6 bits (83), Expect = 0.066 Identities = 22/93 (23%), Positives = 47/93 (50%) Frame = +3 Query: 24 LKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDNS 203 + ++L E + + EL+ L D + + + + + + + L E NE+ R +++ Sbjct: 513 VNQRLLEVQSQVEELQKSLQDQGSKAEDSVLLKKKLEEHLEKLHEANNELQKKRAIIEDL 572 Query: 204 EAERAQHLKQIHDLQEHLREKESQYLALEEQHR 302 E +I +LQE LR+KE + +EE+++ Sbjct: 573 EPRFNNSSLRIEELQEALRKKEEEMKQMEERYK 605 Score = 32.0 bits (71), Expect = 1.6 Identities = 49/214 (22%), Positives = 99/214 (46%), Gaps = 13/214 (6%) Frame = +3 Query: 21 KLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDN 200 KL ++ + EK L L+ L+D + + L+ +++ V NQ LL Q+ ++ ++ L + Sbjct: 478 KLNQEDSDNEKIAL-LQSLLDDANLRKNELETENRLV--NQRLLEVQS-QVEELQKSLQD 533 Query: 201 --SEAERA--------QHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDA 350 S+AE + +HL+++H+ L++K + LE + +N + E+L++A Sbjct: 534 QGSKAEDSVLLKKKLEEHLEKLHEANNELQKKRAIIEDLEPRF----NNSSLRIEELQEA 589 Query: 351 HAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIE 530 R +E ++ Q + + E+ + + + QG IQ L+ +L E Sbjct: 590 ----LRKKEEEMKQMEERYKKYLEKAK------SVIRTLDPKQNQGAAPEIQALKNQLQE 639 Query: 531 LRDR---TGEQDVSQAAQDGSAESSYVQSKGSSM 623 RDR + E++ + E Y+ S +M Sbjct: 640 -RDRLFHSLEKEYEKTKSQRDMEEKYIVSAWYNM 672
>HOOK3_HUMAN (Q86VS8) Hook homolog 3 (hHK3)| Length = 718 Score = 36.6 bits (83), Expect = 0.066 Identities = 22/93 (23%), Positives = 47/93 (50%) Frame = +3 Query: 24 LKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDNS 203 + ++L E + + EL+ L D + + + + + + + L E NE+ R +++ Sbjct: 513 VNQRLLEVQSQVEELQKSLQDQGSKAEDSVLLKKKLEEHLEKLHEANNELQKKRAIIEDL 572 Query: 204 EAERAQHLKQIHDLQEHLREKESQYLALEEQHR 302 E +I +LQE LR+KE + +EE+++ Sbjct: 573 EPRFNNSSLKIEELQEALRKKEEEMKQMEERYK 605 Score = 33.1 bits (74), Expect = 0.73 Identities = 50/214 (23%), Positives = 99/214 (46%), Gaps = 13/214 (6%) Frame = +3 Query: 21 KLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDN 200 KL ++ + EK L L+ L+D + + L+ +++ V NQ LL Q+ ++ ++ L + Sbjct: 478 KLNQEGSDNEKIAL-LQSLLDDANLRKNELETENRLV--NQRLLEVQS-QVEELQKSLQD 533 Query: 201 --SEAERA--------QHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDA 350 S+AE + +HL+++H+ L++K + LE + +N K E+L++A Sbjct: 534 QGSKAEDSVLLKKKLEEHLEKLHEANNELQKKRAIIEDLEPRF----NNSSLKIEELQEA 589 Query: 351 HAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIE 530 R +E ++ Q + + E+ + + + QG IQ L+ +L E Sbjct: 590 ----LRKKEEEMKQMEERYKKYLEKAK------SVIRTLDPKQNQGAAPEIQALKNQLQE 639 Query: 531 LRDR---TGEQDVSQAAQDGSAESSYVQSKGSSM 623 RDR + E++ + E Y+ S +M Sbjct: 640 -RDRLFHSLEKEYEKTKSQREMEEKYIVSAWYNM 672
>KINH_STRPU (P35978) Kinesin heavy chain| Length = 1031 Score = 36.6 bits (83), Expect = 0.066 Identities = 47/199 (23%), Positives = 82/199 (41%), Gaps = 10/199 (5%) Frame = +3 Query: 3 HVVAAEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASF 182 H + L E + E E LE L+ + E+ L+ + +Q+ + + + Sbjct: 629 HEAKMKSLSENIRETEGKKRHLEDSLDMLNEEIVKLRAAEEIRLTDQEDKKREEEDKMQS 688 Query: 183 RRELDNS-----EAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDE-QLR 344 E+ S E+ R H KQ+ +L+ + EKE Q +EE V Q L ++ QL Sbjct: 689 ATEMQASMSEQMESHRDAHQKQLANLRTEINEKEHQ---MEELKDVNQRMTLQHEKLQLD 745 Query: 345 DAHAWITRVQEMDILQSQSLQAELRERTDQ----FGQCWATFQQQYVEMQQGFLHTIQRL 512 I ++ L+ S Q + RE+ Q + A Q +++ F+ +Q Sbjct: 746 YEKLKIEEAEKAAKLRELSQQFDRREQAKQDLKGLEETVAKELQTLHNLRKLFVSDLQNR 805 Query: 513 QLELIELRDRTGEQDVSQA 569 + +E DR + SQA Sbjct: 806 VKKALEGGDRDDDSGGSQA 824 Score = 31.2 bits (69), Expect = 2.8 Identities = 25/95 (26%), Positives = 46/95 (48%), Gaps = 3/95 (3%) Frame = +3 Query: 156 EQTNEIASFRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNI--LYK 329 E +I + ELD+ QH ++ L E++RE E + LE+ + + I L Sbjct: 607 ENETKIRTSEDELDSCRMTIQQHEAKMKSLSENIRETEGKKRHLEDSLDMLNEEIVKLRA 666 Query: 330 DEQLRDAHAWITRVQEMDILQSQS-LQAELRERTD 431 E++R + +E D +QS + +QA + E+ + Sbjct: 667 AEEIRLTDQEDKKREEEDKMQSATEMQASMSEQME 701
>EP15R_HUMAN (Q9UBC2) Epidermal growth factor receptor substrate 15-like 1| (Eps15-related protein) (Eps15R) Length = 864 Score = 36.6 bits (83), Expect = 0.066 Identities = 42/160 (26%), Positives = 74/160 (46%), Gaps = 20/160 (12%) Frame = +3 Query: 150 LREQTNEIASFRREL-----DNSEAERA--QHLKQIHDLQEHLREKESQYLALEEQHRVA 308 L + + EIA +RE D E E A Q ++ +LQ L + S LE Q + A Sbjct: 386 LDDISQEIAQLQREKYSLEQDIREKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQDA 445 Query: 309 QDNILYKDEQ---LRDAHAWI-------TRVQEMDILQSQSLQAELRERTDQFGQCWA-- 452 QD + D+Q LRD + + T++ Q QS +++L+ + D + + Sbjct: 446 QDRLDEMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKSQEDDLNRAKSEL 505 Query: 453 -TFQQQYVEMQQGFLHTIQRLQLELIELRDRTGEQDVSQA 569 QQ+ +++Q R+QLE I ++ + +++QA Sbjct: 506 NRLQQEETQLEQSI--QAGRVQLETIIKSLKSTQDEINQA 543
>CL190_DROME (Q9VJE5) Restin homolog (Cytoplasmic linker protein 190)| (Microtubule-binding protein 190) (d-CLIP-190) Length = 1690 Score = 36.6 bits (83), Expect = 0.066 Identities = 35/191 (18%), Positives = 89/191 (46%), Gaps = 6/191 (3%) Frame = +3 Query: 15 AEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRREL 194 A+ E+L E+ I E +L +TH +LD + + + ++ L++ ++E Sbjct: 1159 ADMNSERLIEKVTGIKE---ELKETHLQLDERQKKFEEL---EEKLKQAQQSEQKLQQES 1212 Query: 195 DNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWI---- 362 S+ + + + + +LQ+ +++KE LEE+ R + I ++ +L +++ + Sbjct: 1213 QTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKT 1272 Query: 363 --TRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELR 536 + + +L+SQ + +L+E + Q+ +++ + + +++ +L+ Sbjct: 1273 SCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQ 1332 Query: 537 DRTGEQDVSQA 569 T + D QA Sbjct: 1333 AATSQLDAQQA 1343 Score = 30.4 bits (67), Expect = 4.8 Identities = 23/108 (21%), Positives = 49/108 (45%) Frame = +3 Query: 48 EKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDNSEAERAQHL 227 EK+ L E + + REL+ LK +++ ++ A F R+L E + Sbjct: 544 EKFSLS-ECGIENLRRELELLKEENE---------KQAQEAQAEFTRKLAEKSVEVLRLS 593 Query: 228 KQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRV 371 ++ +L+ ES+ + ++ + Q + +DEQ+R+ + + V Sbjct: 594 SELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEV 641
>SMC3_RAT (P97690) Structural maintenance of chromosome 3 (Chondroitin| sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) Length = 1191 Score = 36.2 bits (82), Expect = 0.087 Identities = 41/175 (23%), Positives = 72/175 (41%), Gaps = 33/175 (18%) Frame = +3 Query: 18 EKLKEQLHEREKY-----ILELEM---KLNDTHRELDTLKIDHQAVW--------ANQDL 149 E+ KE+L + +K+ LE + +LN+T +LD L + A QD Sbjct: 204 EEEKEELAQYQKWDKMRRALEYTIYNQELNETRAKLDELSAKRETSGEKSRQLRDAQQDA 263 Query: 150 ----------LREQTNEIASFRRELDNSEAERAQHLKQ-------IHDLQEHLREKESQY 278 +RE +I++ + E + AER + +KQ DLQ+ L Q Sbjct: 264 RDKMEDIERQVRELKTKISAMKEEKEQLSAERQEQIKQRTKLELKAKDLQDELAGNSEQR 323 Query: 279 LALEEQHRVAQDNILYKDEQLRDAHAWITRVQEMDILQSQSLQAELRERTDQFGQ 443 L ++ + + I K ++L + V+E + L +ERTD + + Sbjct: 324 KRLLKERQKLLEKIEEKQKELAETEPKFNSVKEKEERGIARLAQATQERTDLYAK 378 Score = 30.0 bits (66), Expect = 6.2 Identities = 48/200 (24%), Positives = 78/200 (39%), Gaps = 28/200 (14%) Frame = +3 Query: 21 KLKEQLHEREKYILELEMKLNDTHR--------ELDTLKIDHQAVWANQ---DLLREQT- 164 +L++ + + E+ + ELE KLN+ R E+D L Q + Q R+ T Sbjct: 677 ELQKDVRKAEEELGELEAKLNENLRRNIERINNEIDQLMNQMQQIETQQRKFKASRDSTL 736 Query: 165 NEIASFRRELDNSEAERAQHLKQIHDLQEHLREKES--------------QYLALEEQHR 302 +E+ + + SE + + L+ L ES L+LE+Q R Sbjct: 737 SEMKMLKEKRQQSEKTFMPKQRSLQSLEASLHAMESTRESLKAELGTDLPSQLSLEDQKR 796 Query: 303 VAQDNILYKDEQLRDAHAWITRVQEMDILQ--SQSLQAELRERTDQFGQCWATFQQQYVE 476 V N + Q ++ R++ I+ L LR+R DQ Q + E Sbjct: 797 VDALNDEIRQLQQKNRQLLNERIKLEGIITRVETYLNENLRKRLDQVEQ----ELNELRE 852 Query: 477 MQQGFLHTIQRLQLELIELR 536 + G + T QLE I R Sbjct: 853 TEGGTVLTATTSQLEAINKR 872
>CTRO_MOUSE (P49025) Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK)| (Rho-interacting, serine/threonine-protein kinase 21) Length = 2055 Score = 36.2 bits (82), Expect = 0.087 Identities = 47/194 (24%), Positives = 87/194 (44%), Gaps = 2/194 (1%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDL-LREQTNEIASFRREL 194 EK+ Q H + +LELE +L + E + K++ + L L+E+ +++ + L Sbjct: 879 EKISHQDHSDKSRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTA----L 934 Query: 195 DNSEAERAQHLKQIH-DLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRV 371 + A L+Q +L+E E E + AL HR D I K + LR++ IT + Sbjct: 935 QAARAALESQLRQAKTELEETTAEAEEEIQAL-TAHR---DEIQRKFDALRNSCTVITDL 990 Query: 372 QEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDRTGE 551 +E + Q AEL + + + ++ G I +L+ E+ LR E Sbjct: 991 EE-QLNQLTEDNAELNNQN--------FYLSKQLDEASGANDEIVQLRSEVDHLRREITE 1041 Query: 552 QDVSQAAQDGSAES 593 +++ +Q + E+ Sbjct: 1042 REMQLTSQKQTMEA 1055 Score = 35.0 bits (79), Expect = 0.19 Identities = 29/133 (21%), Positives = 61/133 (45%), Gaps = 2/133 (1%) Frame = +3 Query: 21 KLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQA-VWANQDLLREQTNEIASFRRELD 197 +L+ L ++ + ++ ++ + ++ +H+A + A Q L+EQ + S +L+ Sbjct: 1104 ELQRMLDTEKQSRARADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLN 1163 Query: 198 NSEAERAQHLKQIHDLQEHLR-EKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQ 374 + E + A LQ+ L E+E + LEEQ ++ Q L K+ R + Sbjct: 1164 DLEKKHAMLEMNARSLQQKLETERELKQRLLEEQAKLQQQMDLQKNHIFRLTQGLQEALD 1223 Query: 375 EMDILQSQSLQAE 413 D+L+++ E Sbjct: 1224 RADLLKTERSDLE 1236 Score = 33.1 bits (74), Expect = 0.73 Identities = 40/170 (23%), Positives = 77/170 (45%), Gaps = 13/170 (7%) Frame = +3 Query: 15 AEKLKEQLHERE-------KYILELEMK---LNDTHRELDTLKIDHQAVWANQDLLREQT 164 AE+ E+LH RE K ++E E + L + + L+T++ + + EQ Sbjct: 668 AERELEKLHNREDSSEGIKKKLVEAEERRHSLENKVKRLETMERRENRLKDDIQTKSEQI 727 Query: 165 NEIASFRRELDNSEAER---AQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDE 335 ++A EL+ E AQHL + HL++KE Y EE+ +V DN + KD Sbjct: 728 QQMADKILELEEKHREAQVSAQHL------EVHLKQKEQHY---EEKIKVL-DNQIKKDL 777 Query: 336 QLRDAHAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQ 485 +++ + + E + + + +E + + + +Q+ VE+ + Sbjct: 778 ADKESLENMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSE 827 Score = 31.2 bits (69), Expect = 2.8 Identities = 38/171 (22%), Positives = 73/171 (42%), Gaps = 5/171 (2%) Frame = +3 Query: 57 ILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQ--TNEIASFRRELDNSEAERAQHLK 230 I +LE +LN D ++++Q + ++ L +EI R E+D+ E + Sbjct: 987 ITDLEEQLNQLTE--DNAELNNQNFYLSKQLDEASGANDEIVQLRSEVDHLRREITEREM 1044 Query: 231 QIHDLQEHLREKESQYLALEEQ---HRVAQDNILYKDEQLRDAHAWITRVQEMDILQSQS 401 Q+ ++ + ++ LEEQ D +L K+ Q AW + + + + Q + Sbjct: 1045 QLTSQKQTMEALKTTCTMLEEQVLDLEALNDELLEKERQW---EAWRSVLGD-EKSQFEC 1100 Query: 402 LQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDRTGEQ 554 EL+ D Q A Q+ E +Q ++ + E++ L+ EQ Sbjct: 1101 RVRELQRMLDTEKQSRARADQRITESRQVVELAVKEHKAEILALQQALKEQ 1151
>CTRO_HUMAN (O14578) Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK)| (Rho-interacting, serine/threonine-protein kinase 21) Length = 2027 Score = 36.2 bits (82), Expect = 0.087 Identities = 47/194 (24%), Positives = 87/194 (44%), Gaps = 2/194 (1%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDL-LREQTNEIASFRREL 194 EK+ Q H + +LELE +L + E + K++ + L L+E+ +++ + L Sbjct: 838 EKISHQDHSDKNRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTA----L 893 Query: 195 DNSEAERAQHLKQIH-DLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRV 371 + A L+Q +L+E E E + AL HR D I K + LR++ IT + Sbjct: 894 QAARAALESQLRQAKTELEETTAEAEEEIQAL-TAHR---DEIQRKFDALRNSCTVITDL 949 Query: 372 QEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDRTGE 551 +E + Q AEL + + + ++ G I +L+ E+ LR E Sbjct: 950 EE-QLNQLTEDNAELNNQN--------FYLSKQLDEASGANDEIVQLRSEVDHLRREITE 1000 Query: 552 QDVSQAAQDGSAES 593 +++ +Q + E+ Sbjct: 1001 REMQLTSQKQTMEA 1014 Score = 35.0 bits (79), Expect = 0.19 Identities = 29/133 (21%), Positives = 61/133 (45%), Gaps = 2/133 (1%) Frame = +3 Query: 21 KLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQA-VWANQDLLREQTNEIASFRRELD 197 +L+ L ++ + ++ ++ + ++ +H+A + A Q L+EQ + S +L+ Sbjct: 1063 ELQRMLDTEKQSRARADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLN 1122 Query: 198 NSEAERAQHLKQIHDLQEHLR-EKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQ 374 + E + A LQ+ L E+E + LEEQ ++ Q L K+ R + Sbjct: 1123 DLEKKHAMLEMNARSLQQKLETERELKQRLLEEQAKLQQQMDLQKNHIFRLTQGLQEALD 1182 Query: 375 EMDILQSQSLQAE 413 D+L+++ E Sbjct: 1183 RADLLKTERSDLE 1195 Score = 31.2 bits (69), Expect = 2.8 Identities = 38/171 (22%), Positives = 73/171 (42%), Gaps = 5/171 (2%) Frame = +3 Query: 57 ILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQ--TNEIASFRRELDNSEAERAQHLK 230 I +LE +LN D ++++Q + ++ L +EI R E+D+ E + Sbjct: 946 ITDLEEQLNQLTE--DNAELNNQNFYLSKQLDEASGANDEIVQLRSEVDHLRREITEREM 1003 Query: 231 QIHDLQEHLREKESQYLALEEQ---HRVAQDNILYKDEQLRDAHAWITRVQEMDILQSQS 401 Q+ ++ + ++ LEEQ D +L K+ Q AW + + + + Q + Sbjct: 1004 QLTSQKQTMEALKTTCTMLEEQVMDLEALNDELLEKERQW---EAWRSVLGD-EKSQFEC 1059 Query: 402 LQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDRTGEQ 554 EL+ D Q A Q+ E +Q ++ + E++ L+ EQ Sbjct: 1060 RVRELQRMLDTEKQSRARADQRITESRQVVELAVKEHKAEILALQQALKEQ 1110 Score = 29.6 bits (65), Expect = 8.1 Identities = 26/99 (26%), Positives = 49/99 (49%) Frame = +3 Query: 48 EKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDNSEAERAQHL 227 EK E ++K+ + +L+ +AV A+ E T + + R+ + +E E + L Sbjct: 628 EKINAEQQLKIQELQEKLE------KAVKAST----EATELLQNIRQAKERAERE-LEKL 676 Query: 228 KQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLR 344 + D E +R+K + LEE+HR AQ + + + L+ Sbjct: 677 QNREDSSEGIRKKLVEAEELEEKHREAQVSAQHLEVHLK 715
>TRHY_HUMAN (Q07283) Trichohyalin| Length = 1898 Score = 36.2 bits (82), Expect = 0.087 Identities = 46/193 (23%), Positives = 87/193 (45%), Gaps = 7/193 (3%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELD 197 ++L+ + R + L E +L E + + H+ Q L REQ +RE + Sbjct: 424 QQLRREQQLRREQQLRREQQLRREQEE-ERHEQKHEQERREQRLKREQEERRDWLKREEE 482 Query: 198 NSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLR-----DAHAWI 362 E+ + +Q+ QE E+ ++L LEE+ R Q +++QLR + Sbjct: 483 TERHEQERRKQQLKRDQE--EERRERWLKLEEEERREQQE--RREQQLRREQEERREQRL 538 Query: 363 TRVQEMDILQS--QSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELR 536 R +E + LQ +S Q RE+ ++ Q +++ +E ++ QRL+ E E R Sbjct: 539 KRQEEEERLQQRLRSEQQLRREQEERLEQLLKREEEKRLEQER----REQRLKREQEERR 594 Query: 537 DRTGEQDVSQAAQ 575 D+ +++ + Q Sbjct: 595 DQLLKREEERRQQ 607 Score = 33.5 bits (75), Expect = 0.56 Identities = 43/189 (22%), Positives = 83/189 (43%), Gaps = 5/189 (2%) Frame = +3 Query: 27 KEQLHERE-KYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDNS 203 +E LH+ + + LE E +L + RE LK + Q ++ LR+ + FR E Sbjct: 1323 EELLHQEQGRKFLEEEQRLRE-ERERKFLKEEQQLRLEEREQLRQDRDR--KFREEEQQL 1379 Query: 204 EAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQ-LRDAHAWITRVQEM 380 + + + Q +E+E ++L E+Q R + ++EQ L++ QE Sbjct: 1380 SRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQER 1439 Query: 381 D---ILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDRTGE 551 D + + Q L+ + R+R + + + ++ ++ LH QR + L E + + Sbjct: 1440 DRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQ 1499 Query: 552 QDVSQAAQD 578 + Q QD Sbjct: 1500 ERGQQRRQD 1508 Score = 33.5 bits (75), Expect = 0.56 Identities = 35/158 (22%), Positives = 69/158 (43%) Frame = +3 Query: 12 AAEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRE 191 A L+EQL + ++ + E E +L RE + + + + ++ L+++ ++ RE Sbjct: 908 AKPALQEQLRKEQQLLQEEEEELQREERE-KRRRQEQERQYREEEQLQQEEEQLLREERE 966 Query: 192 LDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRV 371 + Q+ K + L++KE Q L E + R Q+ ++++ R Sbjct: 967 KRRRQERERQYRKD-----KKLQQKEEQLLGEEPEKRRRQE----REKKYR--------- 1008 Query: 372 QEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQ 485 E + LQ + Q ER + Q W ++ E+QQ Sbjct: 1009 -EEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQ 1045 Score = 33.1 bits (74), Expect = 0.73 Identities = 36/150 (24%), Positives = 63/150 (42%), Gaps = 10/150 (6%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRE-LDTLKIDHQAVWANQDLLREQTNEIASFRREL 194 E+ Q EREK + LE + RE L+ + + +Q+ R++ +R +L Sbjct: 836 EQRGRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRQEQRRDQKWRWQL 895 Query: 195 DNSEAERAQHLKQIHDLQEHLR---------EKESQYLALEEQHRVAQDNILYKDEQLRD 347 + R L LQE LR E+E Q E++ R Q+ ++EQL+ Sbjct: 896 EEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQ 955 Query: 348 AHAWITRVQEMDILQSQSLQAELRERTDQF 437 +E +L+ + + +ER Q+ Sbjct: 956 --------EEEQLLREEREKRRRQERERQY 977 Score = 33.1 bits (74), Expect = 0.73 Identities = 27/94 (28%), Positives = 43/94 (45%) Frame = +3 Query: 30 EQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDNSEA 209 E+L + E+ L+ + + R + LK + Q ++ L REQ E R + + E Sbjct: 627 ERLEQEERRDERLKREEPEEERRHELLKSEEQEERRHEQLRREQ-QERREQRLKREEEEE 685 Query: 210 ERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQ 311 Q LK+ EH E+ Q LA EEQ + + Sbjct: 686 RLEQRLKR-----EHEEERREQELAEEEQEQARE 714 Score = 31.2 bits (69), Expect = 2.8 Identities = 33/139 (23%), Positives = 61/139 (43%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELD 197 EKL+E+ +R++ + E E +L R+ L+ + Q E+ + RRE Sbjct: 258 EKLQEEEPQRQRELQEEEEQLRKLERQ--ELRRERQ----------EEEQQQQRLRREQQ 305 Query: 198 NSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQE 377 + + +Q + +E +E Q E+Q R Q+ +++QLR R QE Sbjct: 306 LRRKQEEERREQQEERREQQERREQQEERREQQLRREQEE--RREQQLR-------REQE 356 Query: 378 MDILQSQSLQAELRERTDQ 434 + + Q + + ER +Q Sbjct: 357 EERREQQLRREQEEERREQ 375 Score = 30.8 bits (68), Expect = 3.6 Identities = 40/165 (24%), Positives = 72/165 (43%), Gaps = 9/165 (5%) Frame = +3 Query: 18 EKLKEQLHEREKY--ILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRE 191 E +EQL +E+Y ILE E +L E + + + ++ LR+ E +E Sbjct: 1689 ETEQEQLRRQERYRKILE-EEQLRPEREEQQLRRQERDRKFREEEQLRQGREEQQLRSQE 1747 Query: 192 LDNSEAERAQHLKQIHDLQEHLREKESQY------LALEEQ-HRVAQDNILYKDEQLRDA 350 D E Q ++ + Q ++++ +Y L LEEQ R+ Q+ +D Q R Sbjct: 1748 SDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQE----RDRQYRAE 1803 Query: 351 HAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQ 485 + T QE + Q L E ++ Q + +++++ QQ Sbjct: 1804 EQFAT--QEKSRREEQELWQEEEQKRRQERE--RKLREEHIRRQQ 1844 Score = 30.0 bits (66), Expect = 6.2 Identities = 42/195 (21%), Positives = 83/195 (42%), Gaps = 11/195 (5%) Frame = +3 Query: 27 KEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDNSE 206 ++QL ++ E +++ R L+ + Q + Q L REQ RRE + Sbjct: 399 EQQLRREQQLRREQQLRREQQLRREQQLRREQQ-LRREQQLRREQ-----QLRREQEEER 452 Query: 207 AE-------RAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWIT 365 E R Q LK+ + + ++E + E++ R Q L +D++ W+ Sbjct: 453 HEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQ---LKRDQEEERRERWLK 509 Query: 366 RVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLE----LIEL 533 +E Q + + +LR ++ + Q++ +QQ L + Q+L+ E L +L Sbjct: 510 LEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQR-LRSEQQLRREQEERLEQL 568 Query: 534 RDRTGEQDVSQAAQD 578 R E+ + Q ++ Sbjct: 569 LKREEEKRLEQERRE 583
>RAD50_AQUAE (O67124) Probable DNA double-strand break repair rad50 ATPase| Length = 978 Score = 36.2 bits (82), Expect = 0.087 Identities = 28/103 (27%), Positives = 55/103 (53%), Gaps = 1/103 (0%) Frame = +3 Query: 9 VAAEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRR 188 V AE + E H +E + E E + DT TLK+ Q + + ++ + + NE+ R+ Sbjct: 501 VDAEGISELKHAKE--LKEKEEREIDT-----TLKLYAQKINSLKEEMEKLRNEVEELRK 553 Query: 189 ELDNSEAERAQHLKQIHDLQEHLREKESQY-LALEEQHRVAQD 314 E+ + ER + L+++ +E L K ++Y ALE++ + ++ Sbjct: 554 EIPENLKERIKKLEELRIEKEKLEHKLNKYRKALEDRQKQKEE 596
>HMW2_MYCGE (P47460) Cytadherence high molecular weight protein 2 (Cytadherence| accessory protein 2) Length = 1805 Score = 36.2 bits (82), Expect = 0.087 Identities = 45/213 (21%), Positives = 87/213 (40%), Gaps = 11/213 (5%) Frame = +3 Query: 21 KLKEQLHEREKYILELEMKLNDTHRELDTL----KIDHQAVWANQDLLREQTNEIASF-- 182 + K + + + +L E +L + RE+DTL ++++ + LL+++ NE+ Sbjct: 394 EFKNESATKSEELLNQERELFEKRREIDTLLTQASLEYEHQRESSQLLKDKQNEVKQHFQ 453 Query: 183 -----RRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRD 347 ++ELD Q K + L+EK +Q E+ Sbjct: 454 NLEYAKKELDKERNLLDQQKKVDSEAIFQLKEKVAQ-------------------ERKEL 494 Query: 348 AHAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELI 527 ++ + Q+ D +++ L E Q Q A F+ + QQ L+ I Sbjct: 495 EELYLVKKQKQDQKENELLFFE-----KQLKQHQADFENELEAKQQELFEAKHALERSFI 549 Query: 528 ELRDRTGEQDVSQAAQDGSAESSYVQSKGSSMA 626 +L D+ E+D++ AQ + E S +++ S A Sbjct: 550 KLEDK--EKDLNTKAQQIANEFSQLKTDKSKSA 580
>RO52_MOUSE (Q62191) 52 kDa Ro protein (Sjoegren syndrome type A antigen)| (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif protein 21) Length = 470 Score = 36.2 bits (82), Expect = 0.087 Identities = 29/101 (28%), Positives = 48/101 (47%), Gaps = 2/101 (1%) Frame = +3 Query: 9 VAAEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRR 188 V EKL++ EK ++L M+ D R +DT K A +A Q+ L Q + R Sbjct: 145 VVLEKLRKGKELAEKMEMDLTMQRTDWKRNIDTQKSRIHAEFALQNSLLAQEEQ-----R 199 Query: 189 ELDNSEAERAQHLKQIHDLQEHLREKES--QYLALEEQHRV 305 +L E ++ ++L+ + + L EK Q L E + R+ Sbjct: 200 QLQRLEKDQREYLRLLGKKEAELAEKNQALQELISELERRI 240
>SMC3_PONPY (Q5R4K5) Structural maintenance of chromosome 3 (Chondroitin| sulfate proteoglycan 6) Length = 1217 Score = 36.2 bits (82), Expect = 0.087 Identities = 41/175 (23%), Positives = 72/175 (41%), Gaps = 33/175 (18%) Frame = +3 Query: 18 EKLKEQLHEREKY-----ILELEM---KLNDTHRELDTLKIDHQAVW--------ANQDL 149 E+ KE+L + +K+ LE + +LN+T +LD L + A QD Sbjct: 204 EEEKEELAQYQKWDKMRRALEYTIYNQELNETRAKLDELSAKRETSGEKSRQLRDAQQDA 263 Query: 150 ----------LREQTNEIASFRRELDNSEAERAQHLKQ-------IHDLQEHLREKESQY 278 +RE +I++ + E + AER + +KQ DLQ+ L Q Sbjct: 264 RDKMEDIERQVRELKTKISAMKEEKEQLSAERQEQIKQRTKLELKAKDLQDELAGNSEQR 323 Query: 279 LALEEQHRVAQDNILYKDEQLRDAHAWITRVQEMDILQSQSLQAELRERTDQFGQ 443 L ++ + + I K ++L + V+E + L +ERTD + + Sbjct: 324 KRLLKERQKLLEKIEEKQKELAETEPKFNSVKEKEERGIARLAQATQERTDLYAK 378
>SMC3_MOUSE (Q9CW03) Structural maintenance of chromosome 3 (Chondroitin| sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member-interacting protein 1) Length = 1217 Score = 36.2 bits (82), Expect = 0.087 Identities = 41/175 (23%), Positives = 72/175 (41%), Gaps = 33/175 (18%) Frame = +3 Query: 18 EKLKEQLHEREKY-----ILELEM---KLNDTHRELDTLKIDHQAVW--------ANQDL 149 E+ KE+L + +K+ LE + +LN+T +LD L + A QD Sbjct: 204 EEEKEELAQYQKWDKMRRALEYTIYNQELNETRAKLDELSAKRETSGEKSRQLRDAQQDA 263 Query: 150 ----------LREQTNEIASFRRELDNSEAERAQHLKQ-------IHDLQEHLREKESQY 278 +RE +I++ + E + AER + +KQ DLQ+ L Q Sbjct: 264 RDKMEDIERQVRELKTKISAMKEEKEQLSAERQEQIKQRTKLELKAKDLQDELAGNSEQR 323 Query: 279 LALEEQHRVAQDNILYKDEQLRDAHAWITRVQEMDILQSQSLQAELRERTDQFGQ 443 L ++ + + I K ++L + V+E + L +ERTD + + Sbjct: 324 KRLLKERQKLLEKIEEKQKELAETEPKFNSVKEKEERGIARLAQATQERTDLYAK 378
>SMC3_HUMAN (Q9UQE7) Structural maintenance of chromosome 3 (Chondroitin| sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) Length = 1217 Score = 36.2 bits (82), Expect = 0.087 Identities = 41/175 (23%), Positives = 72/175 (41%), Gaps = 33/175 (18%) Frame = +3 Query: 18 EKLKEQLHEREKY-----ILELEM---KLNDTHRELDTLKIDHQAVW--------ANQDL 149 E+ KE+L + +K+ LE + +LN+T +LD L + A QD Sbjct: 204 EEEKEELAQYQKWDKMRRALEYTIYNQELNETRAKLDELSAKRETSGEKSRQLRDAQQDA 263 Query: 150 ----------LREQTNEIASFRRELDNSEAERAQHLKQ-------IHDLQEHLREKESQY 278 +RE +I++ + E + AER + +KQ DLQ+ L Q Sbjct: 264 RDKMEDIERQVRELKTKISAMKEEKEQLSAERQEQIKQRTKLELKAKDLQDELAGNSEQR 323 Query: 279 LALEEQHRVAQDNILYKDEQLRDAHAWITRVQEMDILQSQSLQAELRERTDQFGQ 443 L ++ + + I K ++L + V+E + L +ERTD + + Sbjct: 324 KRLLKERQKLLEKIEEKQKELAETEPKFNSVKEKEERGIARLAQATQERTDLYAK 378
>EZRA_OCEIH (Q8EPB2) Septation ring formation regulator ezrA| Length = 564 Score = 36.2 bits (82), Expect = 0.087 Identities = 33/113 (29%), Positives = 53/113 (46%), Gaps = 4/113 (3%) Frame = +3 Query: 9 VAAEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQT--NEIASF 182 +A L++++ E EK I E+ +DT E++ L+ + N D+ R T I++ Sbjct: 301 IAKNYLEQRIPEYEKSISEIAATYDDTKLEVEELQKAYFV--ENNDMERFFTIGKTISTL 358 Query: 183 RRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNI--LYKDE 335 R +L E K DLQ + + + LEEQH + +I L KDE Sbjct: 359 REQLKELHKEMDDDQKSHSDLQNIVEDGFDKIEQLEEQHEEFKKSIENLRKDE 411 Score = 30.0 bits (66), Expect = 6.2 Identities = 26/107 (24%), Positives = 53/107 (49%), Gaps = 12/107 (11%) Frame = +3 Query: 111 KIDHQAVWANQDLLREQTNEIASFRRELDNSEAE--------RAQHL--KQIHDLQEHLR 260 K+DHQ W + R+ +I+ + + E + R +H+ K++ D+++HL Sbjct: 28 KVDHQEKWKMDIMARDVAQQISKIKSLNLSGETQEKFELWKGRWEHIITKELPDIEDHLF 87 Query: 261 EKESQYLALEEQHRVAQDNILYK-DEQLRDAHAWITRV-QEMDILQS 395 + E A ++ +NIL + D++L++ I + +E+D L S Sbjct: 88 DAED---AADKFRMKRANNILTEGDQKLQNIEVKIEEILEELDELLS 131
>YD57_SCHPO (Q10310) Hypothetical protein C6C3.07 in chromosome I| Length = 515 Score = 36.2 bits (82), Expect = 0.087 Identities = 40/197 (20%), Positives = 90/197 (45%), Gaps = 5/197 (2%) Frame = +3 Query: 27 KEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASF----RREL 194 K+++ + EK +L++E ++T+ +D +++ Q LL + T I + + +L Sbjct: 16 KDEITQIEKILLKME---DNTYEYVDVFLEKYES---QQKLLLKLTKAITEYLSNLKPQL 69 Query: 195 DNSEAERAQHLKQIHDLQEHLREKES-QYLALEEQHRVAQDNILYKDEQLRDAHAWITRV 371 E +H+K ++ + L + +++ ++ ++ N L K +R++ T Sbjct: 70 SKQENIYVKHIKSSNEAKTELEIFNCYKEISISKEKKI---NSLLK--LVRESAQDYTIN 124 Query: 372 QEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDRTGE 551 +E DIL + A+ +FG ++Q + LH+I+ + E L +GE Sbjct: 125 EENDILYHSEISAKKNASPMEFGDASFDLEKQRLHFANSNLHSIESERNE-SSLSLDSGE 183 Query: 552 QDVSQAAQDGSAESSYV 602 + +G+ E +Y+ Sbjct: 184 SEKKSEEDNGNGEQNYI 200
>SMC3_BOVIN (O97594) Structural maintenance of chromosome 3 (Chondroitin| sulfate proteoglycan 6) Length = 1218 Score = 36.2 bits (82), Expect = 0.087 Identities = 41/175 (23%), Positives = 72/175 (41%), Gaps = 33/175 (18%) Frame = +3 Query: 18 EKLKEQLHEREKY-----ILELEM---KLNDTHRELDTLKIDHQAVW--------ANQDL 149 E+ KE+L + +K+ LE + +LN+T +LD L + A QD Sbjct: 204 EEEKEELAQYQKWDKMRRALEYTIYNQELNETRAKLDELSAKRETSGEKSRQLRDAQQDA 263 Query: 150 ----------LREQTNEIASFRRELDNSEAERAQHLKQ-------IHDLQEHLREKESQY 278 +RE +I++ + E + AER + +KQ DLQ+ L Q Sbjct: 264 RDKMEDIERQVRELKTKISAMKEEKEQLSAERQEQIKQRTKLELKAKDLQDELAGNSEQR 323 Query: 279 LALEEQHRVAQDNILYKDEQLRDAHAWITRVQEMDILQSQSLQAELRERTDQFGQ 443 L ++ + + I K ++L + V+E + L +ERTD + + Sbjct: 324 KRLLKERQKLLEKIEEKQKELAETEPKFNSVKEKEERGIARLAQATQERTDLYAK 378
>MYSP_TAESO (P35418) Paramyosin (Antigen B) (AgB)| Length = 863 Score = 36.2 bits (82), Expect = 0.087 Identities = 45/210 (21%), Positives = 82/210 (39%), Gaps = 38/210 (18%) Frame = +3 Query: 9 VAAE--KLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQ----TNE 170 +AAE +L + + E EL+ ++++ E++TL + A+ A+ L+ Q T+ Sbjct: 347 LAAENGELTHRAKQAENLANELQRRIDEMTVEINTLNSANSALEADNMRLKGQVGDLTDR 406 Query: 171 IASFRRE----------------------------LDNSEAERAQHLKQIHDLQEHLREK 266 IA+ RE EAER +HD +E L+E Sbjct: 407 IANLDRENRQLGDQLKETKSALRDANRRLTDLEALRSQLEAERDNLASALHDAEEALKEM 466 Query: 267 ESQYL----ALEEQHRVAQDNILYKDEQLRDAHAWITRVQEMDILQSQSLQAELRERTDQ 434 E++Y+ AL + + KDE+L + TR + E T Sbjct: 467 EAKYVASQNALNHLKSEMEQRLREKDEELENLRKSTTRT--------------IEELTTT 512 Query: 435 FGQCWATFQQQYVEMQQGFLHTIQRLQLEL 524 + F+ +++ + TI L+++L Sbjct: 513 ISEMEVRFKSDMSRLKKKYEATISELEVQL 542
>PCP1_SCHPO (Q92351) Spindle pole body protein pcp1| Length = 1208 Score = 36.2 bits (82), Expect = 0.087 Identities = 32/135 (23%), Positives = 61/135 (45%), Gaps = 6/135 (4%) Frame = +3 Query: 48 EKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDNSEAERAQHL 227 E I +L+ +L++ ELD QDLL E+ +EIA+ +R+++ E + Sbjct: 284 EYEIRQLQNRLDELSEELDVA----------QDLLTEKEDEIATLKRQIEEKENSSSAFE 333 Query: 228 KQIHDLQEHLREKESQYLALEEQHRVAQDNI------LYKDEQLRDAHAWITRVQEMDIL 389 + + HL+E Y L+ + D I L K+++ + H + D + Sbjct: 334 NEENSSYVHLQE---DYAILQAKCDEFADRIQVLTADLEKEKENQIMHESEASIGLTDSM 390 Query: 390 QSQSLQAELRERTDQ 434 Q +LQ +L + ++ Sbjct: 391 QVHTLQEQLHKANEE 405
>GLE1_BOVIN (Q3ZBK7) Nucleoporin GLE1 (GLE1-like protein)| Length = 698 Score = 36.2 bits (82), Expect = 0.087 Identities = 40/138 (28%), Positives = 62/138 (44%), Gaps = 1/138 (0%) Frame = +3 Query: 15 AEKLKEQLHEREKYILELEMKLNDTHRELDTLK-IDHQAVWANQDLLREQTNEIASFRRE 191 AE L++ E+EK + L ++ + D K + H + + LRE + S R Sbjct: 144 AEGLRQWQEEQEKKVRALSEMASEQLKRFDERKELKHHKEFQD---LREVMEK--SSREA 198 Query: 192 LDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRV 371 L E +A+H + L LRE E Q L EEQ R+ ++ +LR +A + Sbjct: 199 LGQQEKLKAEHRHRAKILNLKLREAEQQRLKQEEQERLRKEE---GQARLRGLYA----L 251 Query: 372 QEMDILQSQSLQAELRER 425 QE + SQ L A + R Sbjct: 252 QEEVLHLSQQLDASDQHR 269
>MEDB_GIALA (Q08014) Median body protein| Length = 857 Score = 36.2 bits (82), Expect = 0.087 Identities = 44/187 (23%), Positives = 80/187 (42%), Gaps = 16/187 (8%) Frame = +3 Query: 45 REKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDNSEAERAQH 224 REK LE E+K N + D L Q + ++ + LRE+ + REL + E + Sbjct: 472 REKAALETELKENSYN--FDQLLEQKQQMRSDLNALREKAADYERVDRELRLKDKELEEK 529 Query: 225 LKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRD---AH-------------A 356 +I L E R ++ L +E + L ++++LRD AH Sbjct: 530 NAEIERLLEDRRVMRTELLHSKES--ATDVDSLIQEKRLRDRELAHLRDRMSEYERVVEE 587 Query: 357 WITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELR 536 I + +E ++L+ + + E ++RT + + ++ G+ Q + E+ LR Sbjct: 588 RIQKEKENNLLKQRITELEQQQRTATVRETEMSALREKANELDGYNRERQAREHEINMLR 647 Query: 537 DRTGEQD 557 D+ E D Sbjct: 648 DKALESD 654
>MYSP_SCHJA (Q05870) Paramyosin (Antigen Sj97)| Length = 866 Score = 35.8 bits (81), Expect = 0.11 Identities = 31/126 (24%), Positives = 61/126 (48%) Frame = +3 Query: 57 ILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDNSEAERAQHLKQI 236 I E+E+K EL LK +++ A+ ++ + TN+ + + + + A+R + L+ Sbjct: 517 ITEMEVKYKS---ELSRLKKRYESSIADLEIQLDATNKANANLMKENKNLAQRVKDLETF 573 Query: 237 HDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQEMDILQSQSLQAEL 416 D + LRE L + E R+ N + E+LR A + R+++ + + Q+ + Sbjct: 574 LDDERRLREAAENNLQITEHKRIQLAN---EVEELRSAMENLERLRKHAETELEETQSRV 630 Query: 417 RERTDQ 434 E T Q Sbjct: 631 SELTIQ 636 Score = 34.3 bits (77), Expect = 0.33 Identities = 41/182 (22%), Positives = 77/182 (42%), Gaps = 7/182 (3%) Frame = +3 Query: 6 VVAAEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDH----QAVWANQDLLREQTNEI 173 V E+LK E+ K L LE+K D E+++L +++ + + + L E + Sbjct: 319 VAERERLKAVSLEKLKTKLTLEIK--DLQSEIESLSLENGELIRRAKSAESLASELQRRV 376 Query: 174 ASFRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAH 353 E++ ++ Q + L+ + + + ALE ++R D + LRDA+ Sbjct: 377 DELTIEVNTLTSQNNQLESENMRLKSLVNDLTDKNNALERENRQMNDQVKELKSSLRDAN 436 Query: 354 AWITRVQEMDILQSQSLQAE---LRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLEL 524 R+ +++ L+SQ L+AE L + Q+Y Q H ++ L Sbjct: 437 ---RRLTDLEALRSQ-LEAERDNLASALHDAEEALRDMDQKYQASQAALNHLKSEMEQRL 492 Query: 525 IE 530 E Sbjct: 493 RE 494 Score = 31.6 bits (70), Expect = 2.1 Identities = 29/134 (21%), Positives = 58/134 (43%), Gaps = 11/134 (8%) Frame = +3 Query: 9 VAAEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRR 188 + L Q ++ E + L+ +ND + + L+ +++ + D ++E + + R Sbjct: 381 IEVNTLTSQNNQLESENMRLKSLVNDLTDKNNALERENRQM---NDQVKELKSSLRDANR 437 Query: 189 ELDNSEAERAQHLKQ-------IHDLQEHLREKESQY----LALEEQHRVAQDNILYKDE 335 L + EA R+Q + +HD +E LR+ + +Y AL + + +DE Sbjct: 438 RLTDLEALRSQLEAERDNLASALHDAEEALRDMDQKYQASQAALNHLKSEMEQRLRERDE 497 Query: 336 QLRDAHAWITRVQE 377 +L TR E Sbjct: 498 ELESLRKSTTRTIE 511
>AZI1_HUMAN (Q9UPN4) 5-azacytidine-induced protein 1 (Pre-acrosome localization| protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein) Length = 1083 Score = 35.8 bits (81), Expect = 0.11 Identities = 31/125 (24%), Positives = 53/125 (42%), Gaps = 5/125 (4%) Frame = +3 Query: 216 AQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQEMDILQS 395 ++ K+I ++ E E Q L + V + L++ E L+ R + + Q+ Sbjct: 697 SEKTKKIKEVTVRGLEPEIQKLIARHKQEVRRLKSLHEAELLQSDE----RASQRCLRQA 752 Query: 396 QSLQAELRERTDQFGQ-----CWATFQQQYVEMQQGFLHTIQRLQLELIELRDRTGEQDV 560 + L+ +L + GQ FQQ + Q QRL E+ E R+R G+Q Sbjct: 753 EELREQLEREKEALGQQERERARQRFQQHLEQEQWALQQQRQRLYSEVAEERERLGQQAA 812 Query: 561 SQAAQ 575 Q A+ Sbjct: 813 RQRAE 817 Score = 35.4 bits (80), Expect = 0.15 Identities = 44/154 (28%), Positives = 69/154 (44%), Gaps = 14/154 (9%) Frame = +3 Query: 15 AEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRREL 194 AE+L+EQL EREK L + + R L+ Q WA Q + +E+A R L Sbjct: 752 AEELREQL-EREKEALGQQERERARQRFQQHLE---QEQWALQQQRQRLYSEVAEERERL 807 Query: 195 DNSEAERAQHLKQIHDLQEHLREKESQYL---------ALEEQHRVAQDNILYKDEQLR- 344 + A+ ++ +L++ L E S EEQ R Q + +QL Sbjct: 808 GQ---QAARQRAELEELRQQLEESSSALTRALRAEFEKGREEQERRHQMELNTLKQQLEL 864 Query: 345 DAHAW---ITRVQEMDIL-QSQSLQAELRERTDQ 434 + AW TR +E +L + Q L+ E+R+ D+ Sbjct: 865 ERQAWEAGRTRKEEAWLLNREQELREEIRKGRDK 898 Score = 32.3 bits (72), Expect = 1.3 Identities = 46/197 (23%), Positives = 81/197 (41%), Gaps = 17/197 (8%) Frame = +3 Query: 3 HVVAAEKLKEQLH------------EREKYILELEMKLNDTHRELDTLKIDH--QAVWAN 140 H + LK+QL + E ++L E +L + R+ +I+ + A+ Sbjct: 851 HQMELNTLKQQLELERQAWEAGRTRKEEAWLLNREQELREEIRKGRDKEIELVIHRLEAD 910 Query: 141 QDLLREQTNEIASFR--RELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQD 314 L +E++ + A R R D EAE ++ + LQE E + Q E ++ Q Sbjct: 911 MALAKEESEKAAESRIKRLRDKYEAELSELEQSERKLQERCSELKGQLGEAEGENLRLQG 970 Query: 315 NILYKDEQLRDAHAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFL 494 + K+ L DA A ++ +Q ++ E +R ++ + L Sbjct: 971 LVRQKERALEDAQAVNEQLSSERSNLAQVIRQEFEDR--------LAASEEETRQAKAEL 1022 Query: 495 HTIQ-RLQLELIELRDR 542 T+Q R QLEL E+ R Sbjct: 1023 ATLQARQQLELEEVHRR 1039
>STM2A_XENLA (Q09001) Stathmin-2-A (SCG10 protein homolog A)| Length = 178 Score = 35.8 bits (81), Expect = 0.11 Identities = 23/83 (27%), Positives = 45/83 (54%), Gaps = 3/83 (3%) Frame = +3 Query: 195 DNSEAERAQHLKQIHDLQEHLREKESQYLALEEQH---RVAQDNILYKDEQLRDAHAWIT 365 D +++ AQ LKQ+ + +EH E+E ALEE + R+A++ ++ K EQ+++ + Sbjct: 93 DRRKSQEAQILKQLAEKREH--EREVLQKALEENNNFSRMAEEKLILKMEQIKENREYYL 150 Query: 366 RVQEMDILQSQSLQAELRERTDQ 434 + + + AE+R +Q Sbjct: 151 ASLMERLKEKERHAAEVRRNKEQ 173
>CCD27_HUMAN (Q2M243) Coiled-coil domain-containing protein 27| Length = 656 Score = 35.8 bits (81), Expect = 0.11 Identities = 42/202 (20%), Positives = 84/202 (41%), Gaps = 4/202 (1%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELD 197 E+L QL E E+ IL+ + L T T IAS ++++D Sbjct: 409 EELLAQLEEYEQVILDFQFNLEATRTRYSLA-----------------TGVIASLQQQVD 451 Query: 198 NSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQE 377 E + + + LQ+ LRE+ Q A+ ++ + L +D++ ++ I + + Sbjct: 452 FQETQLRKINTENETLQKELRERRQQLQAMTDKF-----SNLREDKKHQEMMGLIEKDNQ 506 Query: 378 MDILQSQSLQAELRERTDQFGQCWATFQ--QQYVEMQQGFLHTIQRLQLELIELRD--RT 545 + Q L+ +L +R + Q+ VE+ Q L ++LQ +L ++ + Sbjct: 507 LLRQQVSELERKLTKRDCVISELDTKVSQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQ 566 Query: 546 GEQDVSQAAQDGSAESSYVQSK 611 EQ A + + +++K Sbjct: 567 AEQHTRVALESSQSRLERLRNK 588 Score = 35.0 bits (79), Expect = 0.19 Identities = 40/172 (23%), Positives = 76/172 (44%), Gaps = 30/172 (17%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDT-----HRELDTLKIDHQAVWANQDLLREQTNEIAS- 179 E L+++L ER + + + K ++ H+E+ L + + LLR+Q +E+ Sbjct: 465 ETLQKELRERRQQLQAMTDKFSNLREDKKHQEMMGL------IEKDNQLLRQQVSELERK 518 Query: 180 ------FRRELDNSEAERAQ-------HLKQIHDLQEHLREKESQYLALEEQHRVAQDNI 320 ELD ++ + HL++ LQE L+ K+ E+ RVA ++ Sbjct: 519 LTKRDCVISELDTKVSQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESS 578 Query: 321 LYKDEQLRD-----------AHAWITRVQEMDILQSQSLQAELRERTDQFGQ 443 + E+LR+ + + + DIL ++LQ + ER+D + Q Sbjct: 579 QSRLERLRNKIIQATFSISGTKSLANEISDNDIL--EALQRIISERSDYYNQ 628
>MYO1_CAEEL (P02567) Myosin-1 (Myosin heavy chain D) (MHC D)| Length = 1938 Score = 35.8 bits (81), Expect = 0.11 Identities = 43/176 (24%), Positives = 76/176 (43%), Gaps = 29/176 (16%) Frame = +3 Query: 15 AEKLKEQLHEREKYILELEMKLN--------------DTHRELDTL--KIDHQ--AVWAN 140 A +L Q E + I+E+E +L + RELD L ++D Q + Sbjct: 1108 ANRLTRQSKENAQRIIEIEDELEHERQSRSKADRARAELQRELDELNERLDEQNKQLEIQ 1167 Query: 141 QDLLREQTNEIASFRRELDNSEAE--------RAQHLKQIHDLQEHLREKESQYLALEEQ 296 QD +++ +EI FRR+LD R ++ QI L L + +E++ Sbjct: 1168 QDNNKKKDSEIIKFRRDLDEKNMANEDQMAMIRRKNNDQISALTNTLDALQKSKAKIEKE 1227 Query: 297 HRVAQ---DNILYKDEQLRDAHAWITRVQEMDILQSQSLQAELRERTDQFGQCWAT 455 V Q D+I + +Q + R+ + +Q LQ ++ E++ Q G+ +T Sbjct: 1228 KGVLQKELDDINAQVDQETKSRVEQERLAKQYEIQVAELQQKVDEQSRQIGEYTST 1283
>INVO_AOTTR (P24708) Involucrin| Length = 544 Score = 35.8 bits (81), Expect = 0.11 Identities = 48/195 (24%), Positives = 86/195 (44%), Gaps = 12/195 (6%) Frame = +3 Query: 18 EKLKEQLHEREKYIL----ELEMKLNDTHRELDTLKIDHQAVWANQDLLR---EQTNEIA 176 ++LK++ +REK L E E KL D + + K D Q + LL +Q ++ Sbjct: 105 QQLKQEKAQREKQQLQGQLEEEKKLLDQQPDHELAKSDEQLGTKKEQLLEFPEQQEGQLK 164 Query: 177 SFRR-----ELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQL 341 + EL + + + L+Q QE ++E Q LE+Q + QL Sbjct: 165 CLEQQEGHLELPEQQEGQLKCLEQQEGHQELPEQQEGQLKHLEQQ-----------EGQL 213 Query: 342 RDAHAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLE 521 + +V+ L+ Q Q+EL E+ Q GQ +Y+E Q+G L ++ + + Sbjct: 214 KHLEQQEGQVKH---LEQQEKQSELPEQ--QRGQ------PKYLEQQEGQLKHLEEQKGQ 262 Query: 522 LIELRDRTGEQDVSQ 566 L L + G+ ++ + Sbjct: 263 LKHLEHQEGQLELPE 277 Score = 33.9 bits (76), Expect = 0.43 Identities = 53/199 (26%), Positives = 87/199 (43%), Gaps = 22/199 (11%) Frame = +3 Query: 30 EQLHEREKYILELEMKLNDT-HRELDTLKIDHQAVWANQ-DLLREQTNEIASFRRE---L 194 + L ++E+ + LE + H E +++H Q L EQ ++ ++ L Sbjct: 313 KHLEQQEEQLKHLEQQEGQPKHPEQLEKQLEHPEQQEGQLKQLEEQEGQVKHLEQQEEQL 372 Query: 195 DNSEAERAQ--HLKQIHDLQEHLREKESQYLALEE--------QHRVAQDNILYKDE-QL 341 + E + Q HL+Q+ EHL ++E Q LE+ + +V Q L ++E QL Sbjct: 373 KHLEQQEGQPKHLEQLEKQLEHLEQQEGQLKHLEQREEQLELPEQQVGQSKHLEQEEKQL 432 Query: 342 RDAHAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQ----QYVEMQQGFL--HTI 503 + ++ L Q Q EL E Q GQ QQ ++ E Q+G L Sbjct: 433 EHPE---QQEGQLKHLGKQEAQLELPE---QVGQPKHLEQQEKQLEHPEQQEGQLKPQEQ 486 Query: 504 QRLQLELIELRDRTGEQDV 560 Q QL+ +E ++R EQ V Sbjct: 487 QEGQLKGLEQQERQLEQPV 505 Score = 32.3 bits (72), Expect = 1.3 Identities = 45/191 (23%), Positives = 82/191 (42%), Gaps = 21/191 (10%) Frame = +3 Query: 21 KLKEQLHEREKYILELEMKLNDTHRELDTLK-IDHQAVWANQDLLREQTNEIASFRRELD 197 +L EQ + KY+ + E +L + LK ++HQ Q + ++L+ Sbjct: 234 ELPEQQRGQPKYLEQQEGQLKHLEEQKGQLKHLEHQEGQLELPEQVGQPKHLEQLEKQLE 293 Query: 198 NSEAERAQ------------HLKQIHDLQEHLREKESQ-----YLALEEQHRVAQDNILY 326 + E + Q HL+Q + +HL ++E Q L + +H Q+ L Sbjct: 294 HPEQQEGQLKQLEEQEGQVKHLEQQEEQLKHLEQQEGQPKHPEQLEKQLEHPEQQEGQLK 353 Query: 327 K-DEQLRDAHAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFL-HT 500 + +EQ + +++ L+ Q Q + E+ ++ Q +++E Q+G L H Sbjct: 354 QLEEQEGQVKHLEQQEEQLKHLEQQEGQPKHLEQLEK--------QLEHLEQQEGQLKHL 405 Query: 501 IQR-LQLELIE 530 QR QLEL E Sbjct: 406 EQREEQLELPE 416
>ROCK2_HUMAN (O75116) Rho-associated protein kinase 2 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2) Length = 1388 Score = 35.8 bits (81), Expect = 0.11 Identities = 36/153 (23%), Positives = 73/153 (47%), Gaps = 17/153 (11%) Frame = +3 Query: 21 KLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDN 200 +LKE+ E+ K EL+ K + E D+L A L + + ++A E Sbjct: 882 ELKEECEEKTKLGKELQQKKQELQDERDSL-----AAQLEITLTKADSEQLARSIAEEQY 936 Query: 201 SEAERAQHLKQIHDLQ------EHLREKESQYLALEEQHRVAQDNIL----YKDE---QL 341 S+ E+ + +K++ + + L EK++ +LEE +R ++ K+E +L Sbjct: 937 SDLEKEKIMKELEIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEELNNKL 996 Query: 342 RDAHAWITRVQEMDI----LQSQSLQAELRERT 428 +D ++R+++ +I +++Q + L ERT Sbjct: 997 KDVQEQLSRLKDEEISAAAIKAQFEKQLLTERT 1029
>MYSP_CAEEL (P10567) Paramyosin| Length = 882 Score = 35.8 bits (81), Expect = 0.11 Identities = 30/118 (25%), Positives = 52/118 (44%), Gaps = 17/118 (14%) Frame = +3 Query: 12 AAEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLRE----------- 158 AAE+ + Q +E + +L +ND ++ L+ + N DLL+E Sbjct: 191 AAERFEAQANELANKVEDLNKHVNDLAQQRQRLQAE------NNDLLKEVHDQKVQLDNL 244 Query: 159 ------QTNEIASFRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQD 314 ++ RR L+++E ER+Q Q+H +Q E +S AL+E+ D Sbjct: 245 QHVKYTLAQQLEEARRRLEDAERERSQLQSQLHQVQ---LELDSVRTALDEESIARSD 299 Score = 33.5 bits (75), Expect = 0.56 Identities = 44/208 (21%), Positives = 86/208 (41%), Gaps = 6/208 (2%) Frame = +3 Query: 15 AEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRREL 194 A + EQLHE +++ ++KID A + L EQ ++ ++ Sbjct: 706 AARAVEQLHEEQEH----------------SMKID-----ALRKSLEEQVKQL-----QV 739 Query: 195 DNSEAERAQHL---KQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWIT 365 EAE A L + I L+ +R+ E+ +H+ Q+ + KD ++++ + Sbjct: 740 QIQEAEAAALLGGKRVIAKLETRIRDLETALDEETRRHKETQNALRKKDRRIKEVQQLVD 799 Query: 366 RVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDRT 545 + + + +Q L E+ + ++Q E + + +QR++ EL D Sbjct: 800 E-EHKNFVMAQDTADRLTEKLN-------IQKRQLAESESVTMQNLQRVRRYQHELEDAE 851 Query: 546 GEQDVSQAAQD---GSAESSYVQSKGSS 620 G D ++++ SS V K SS Sbjct: 852 GRADQAESSLHLIRAKHRSSVVTGKSSS 879 Score = 30.8 bits (68), Expect = 3.6 Identities = 26/102 (25%), Positives = 48/102 (47%) Frame = +3 Query: 15 AEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRREL 194 AE E+ + R ++ + L +L+T QA L E T E+ + Sbjct: 646 AEVDLEEANGRISDLISINNNLTSIKNKLETELSTAQAD------LDEVTKELHAADERA 699 Query: 195 DNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNI 320 + + A+ A+ ++Q+H+ QEH + ++ +LEEQ + Q I Sbjct: 700 NRALADAARAVEQLHEEQEHSMKIDALRKSLEEQVKQLQVQI 741
>HOOK1_HUMAN (Q9UJC3) Hook homolog 1 (h-hook1) (hHK1)| Length = 728 Score = 35.8 bits (81), Expect = 0.11 Identities = 34/170 (20%), Positives = 84/170 (49%), Gaps = 35/170 (20%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEM-------KLNDTHRELDTLKID----------------HQA 128 E+L+EQL ++ + + ELE ++ + ++++ L+ Q Sbjct: 490 EELQEQLEQKHRKMNELETEQRLSKERIRELQQQIEDLQKSLQEQGSKSEGESSSKLKQK 549 Query: 129 VWANQDLLREQTNEIASFRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRV- 305 + A+ + L E E+ + +++ + + Q++++I++L+ L++K+ A+EE++++ Sbjct: 550 LEAHMEKLTEVHEELQKKQELIEDLQPDINQNVQKINELEAALQKKDEDMKAMEERYKMY 609 Query: 306 ---AQDNILYKDEQLRDAHAWI--------TRVQEMDILQSQSLQAELRE 422 A++ I D +L A A I + + ++IL+S+ A+ R+ Sbjct: 610 LEKARNVIKTLDPKLNPASAEIMLLRKQLAEKERRIEILESECKVAKFRD 659
>GOGA5_RAT (Q3ZU82) Golgin subfamily A member 5 (Golgin-84)| Length = 728 Score = 35.8 bits (81), Expect = 0.11 Identities = 38/172 (22%), Positives = 76/172 (44%), Gaps = 4/172 (2%) Frame = +3 Query: 21 KLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDN 200 +L+E HERE E++ + H+ L QD+ +Q +E S R +L + Sbjct: 464 ELEELRHERELQKEEIQKLMGQIHQLRSEL----------QDMEAQQVSEAESAREQLQD 513 Query: 201 SEAERAQHLKQIHDLQEHL-REKESQYLALEEQHR---VAQDNILYKDEQLRDAHAWITR 368 + + A+ +L+ L R K+ + E+ HR Q I ++E+++ +T Sbjct: 514 LQDQIAKQRASKQELETELDRMKQEFHYVEEDLHRTKNTLQSRIKDREEEIQKLRNQLTN 573 Query: 369 VQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLEL 524 + QS+ L++ L + T+ Q + E + + ++RL+ +L Sbjct: 574 KTLSNSSQSE-LESRLHQLTETLIQKQTLLESLSTE-KNSLVFQLERLEQQL 623 Score = 34.7 bits (78), Expect = 0.25 Identities = 28/126 (22%), Positives = 55/126 (43%), Gaps = 11/126 (8%) Frame = +3 Query: 6 VVAAEKLKEQLHEREKYILELEMKLNDTHRELDTLKID--------HQAVWANQDLLREQ 161 V AE +EQL + + I + + ELD +K + H+ Q ++++ Sbjct: 501 VSEAESAREQLQDLQDQIAKQRASKQELETELDRMKQEFHYVEEDLHRTKNTLQSRIKDR 560 Query: 162 TNEIASFRRELDN---SEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKD 332 EI R +L N S + +++ ++H L E L +K++ +L + + + Sbjct: 561 EEEIQKLRNQLTNKTLSNSSQSELESRLHQLTETLIQKQTLLESLSTEKNSLVFQLERLE 620 Query: 333 EQLRDA 350 +QL A Sbjct: 621 QQLHSA 626
>DESM_CHICK (P02542) Desmin| Length = 463 Score = 35.8 bits (81), Expect = 0.11 Identities = 45/192 (23%), Positives = 79/192 (41%), Gaps = 18/192 (9%) Frame = +3 Query: 15 AEKLKEQLHEREKYILELEMKLNDTHRE----LDTLKIDHQAVWANQDLLREQTNEIASF 182 AE +E+L E + + L + E LD L+ Q + L +E N +A+F Sbjct: 143 AEMYEEELRELRRQVDALTGQRARVEVERDNLLDNLQKLKQKLQEEIQLKQEAENNLAAF 202 Query: 183 RRELDNSEAERAQHLKQIHDLQE--------HLREKESQYLALEEQHRVAQDNILYKD-- 332 R ++D + R ++I LQE H E L+EQH + +I D Sbjct: 203 RADVDAATLARIDLERRIESLQEEIAFLKKVHEEEIRELQAQLQEQHIQVEMDISKPDLT 262 Query: 333 EQLRDAHAWITRVQEMDILQSQ----SLQAELRERTDQFGQCWATFQQQYVEMQQGFLHT 500 LRD A + +I +++ S ++L + ++ +Q+ +E + H Sbjct: 263 AALRDIRAQYESIAAKNIAEAEEWYKSKVSDLTQAANKNNDALRQAKQEMLE----YRHQ 318 Query: 501 IQRLQLELIELR 536 IQ E+ L+ Sbjct: 319 IQSYTCEIDALK 330
>CENPF_HUMAN (P49454) CENP-F kinetochore protein (Centromere protein F) (Mitosin)| (AH antigen) Length = 3210 Score = 35.8 bits (81), Expect = 0.11 Identities = 38/158 (24%), Positives = 69/158 (43%), Gaps = 25/158 (15%) Frame = +3 Query: 24 LKEQLHEREKYILELEMKLNDTHREL-------DTLKIDHQAVWANQDLLREQTNEIAS- 179 + E+L ERE+ L+ K+ + REL + + +D + A + L+ Q E+A Sbjct: 2234 IAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARS 2293 Query: 180 ---FRRELDNSEAERAQHLKQIHDLQEH--------------LREKESQYLALEEQHRVA 308 F +L +E+ KQI + Q L EKE + ++E+ + A Sbjct: 2294 LKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTA 2353 Query: 309 QDNILYKDEQLRDAHAWITRVQEMDILQSQSLQAELRE 422 + + + ++L +A A + QE+ QSL + E Sbjct: 2354 VEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEE 2391
>NIN_HUMAN (Q8N4C6) Ninein (hNinein)| Length = 2090 Score = 35.8 bits (81), Expect = 0.11 Identities = 25/103 (24%), Positives = 50/103 (48%), Gaps = 5/103 (4%) Frame = +3 Query: 24 LKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDNS 203 LK QL ++ + LE + + + ++ +K D + ++ L++ E+ S ++L N+ Sbjct: 1757 LKSQLVASQEKVQNLEDTVQNVNLQMSRMKSDLRVTQQEKEALKQ---EVMSLHKQLQNA 1813 Query: 204 EA-----ERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDN 317 E A H +H+ Q+ L + +L EEQ + Q+N Sbjct: 1814 GGKSWAPEIATHPSGLHNQQKRLSWDKLDHLMNEEQQLLWQEN 1856 Score = 31.6 bits (70), Expect = 2.1 Identities = 50/231 (21%), Positives = 93/231 (40%), Gaps = 30/231 (12%) Frame = +3 Query: 18 EKLKEQLHEREKYI-LELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRREL 194 E++KEQ H + LELE K+ ++LD + + A +++ + NE + Sbjct: 612 EQMKEQHHRDICCLRLELEDKVRHYEKQLDETVVSCKK--AQENMKQRHENETHTLE--- 666 Query: 195 DNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVA---------------QDNILYK 329 KQI DL+ + E + Q L+E H A ++ + Sbjct: 667 -----------KQISDLKNEIAELQGQAAVLKEAHHEATCRHEEEKKQLQVKLEEEKTHL 715 Query: 330 DEQLRDAH-----AWITRVQ-----EMDILQSQSLQAE----LRERTDQFGQCWATFQQQ 467 E+LR H A +T+ Q E + LQS + E L + +QF Q+Q Sbjct: 716 QEKLRLQHEMELKARLTQAQASFEREREGLQSSAWTEEKVRGLTQELEQF------HQEQ 769 Query: 468 YVEMQQGFLHTIQRLQLELIELRDRTGEQDVSQAAQDGSAESSYVQSKGSS 620 + + + L+ EL+E R ++ + + + +S ++++ S Sbjct: 770 LTSLVEKHTLEKEELRKELLEKHQRELQEGREKMETECNRRTSQIEAQFQS 820
>LIPA3_MOUSE (P60469) Liprin-alpha-3 (Protein tyrosine phosphatase receptor type| f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3) Length = 1043 Score = 35.8 bits (81), Expect = 0.11 Identities = 43/173 (24%), Positives = 77/173 (44%), Gaps = 5/173 (2%) Frame = +3 Query: 27 KEQLHEREKYILELEMKLNDTHRELDTLK--IDHQAVWANQDLLREQTNEIASFRRELDN 200 +EQL ERE+ I EL+ + N+T L+ L+ + +++ Q + Sbjct: 93 REQLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPGGV-----S 147 Query: 201 SEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYK--DEQLRDAHAWITRVQ 374 SE E + LK + + + L EK + L + ++ +A LY+ +E+ R W+ + Sbjct: 148 SEVEVLKALKSLFEHHKALDEKVRERLRMALENELASKESLYRQSEEKSRQLAEWLDDAK 207 Query: 375 EMDILQSQSLQAE-LRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIE 530 + LQ +AE L E Q Q A + E F +++L+ +L E Sbjct: 208 QK--LQQTLQKAETLPEIEAQLAQRVAALNKA-EERHGNFEERLRQLEAQLEE 257
>M24_STRPY (P12379) M protein, serotype 24 precursor| Length = 539 Score = 35.8 bits (81), Expect = 0.11 Identities = 38/184 (20%), Positives = 82/184 (44%), Gaps = 4/184 (2%) Frame = +3 Query: 15 AEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRREL 194 A+ K + E EK LE E D + L + Q++ + D RE ++ + ++L Sbjct: 278 ADSAKIKTLEAEKAALEAEKA--DLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKL 335 Query: 195 DN----SEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWI 362 + SEA R + + +E ++ E+++ LEEQ+++++ + L DA Sbjct: 336 EEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDL-DASREA 394 Query: 363 TRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDR 542 + E + ++ S A L + + + +++ E+Q +L+ E L+++ Sbjct: 395 KKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQ-------AKLEAEAKALKEK 447 Query: 543 TGEQ 554 +Q Sbjct: 448 LAKQ 451
>NONO_MOUSE (Q99K48) Non-POU domain-containing octamer-binding protein (NonO| protein) Length = 473 Score = 35.4 bits (80), Expect = 0.15 Identities = 28/99 (28%), Positives = 46/99 (46%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELD 197 E K+Q + ++ I E KL E++ + +HQ + QDL+R Q E EL Sbjct: 278 EMEKQQQDQVDRNIKEAREKLE---MEMEAARHEHQVMLMRQDLMRRQ--EELRRMEELH 332 Query: 198 NSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQD 314 N E ++ + L ++ +E R +E EE R Q+ Sbjct: 333 NQEVQKRKQL-ELRQEEERRRREEEMRRQQEEMMRRQQE 370
>SKI_HORSE (Q9TUG2) Ski oncogene (C-ski)| Length = 730 Score = 35.4 bits (80), Expect = 0.15 Identities = 33/143 (23%), Positives = 67/143 (46%), Gaps = 8/143 (5%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELD 197 E +K ++ + EK L+ K H+EL+ L++ A ++ LRE T + R+E++ Sbjct: 567 EVVKMRVKQEEKLSAALQAK-RSLHQELEFLRV------AKKEKLREATEAKRNLRKEIE 619 Query: 198 NSEAERAQHLKQIHDLQEHLREKESQYLAL-------EEQHRVAQDNILYKDEQLRDAHA 356 AE + +K+ ++ + L+ + Q + E A+ + +D Q++ HA Sbjct: 620 RLRAENEKKMKEANESRLRLKRELEQARQVRVCDKGCEAGRLRAKYSAQIEDLQVKLQHA 679 Query: 357 WITRVQ-EMDILQSQSLQAELRE 422 R Q D+L+ + + L + Sbjct: 680 EADREQLRADLLREREAREHLEK 702
>SKI_MOUSE (Q60698) Ski oncogene (C-ski)| Length = 725 Score = 35.4 bits (80), Expect = 0.15 Identities = 22/86 (25%), Positives = 45/86 (52%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELD 197 E +K ++ + EK L+ K H+EL+ L++ A ++ LRE T + R+E++ Sbjct: 562 EVVKMRVKQEEKLTAALQAK-RTLHQELEFLRV------AKKEKLREATEAKRNLRKEIE 614 Query: 198 NSEAERAQHLKQIHDLQEHLREKESQ 275 AE + +K+ ++ + L+ + Q Sbjct: 615 RLRAENEKKMKEANESRVRLKRELEQ 640
>PEPL_MOUSE (Q9R269) Periplakin| Length = 1755 Score = 35.4 bits (80), Expect = 0.15 Identities = 46/195 (23%), Positives = 86/195 (44%), Gaps = 2/195 (1%) Frame = +3 Query: 21 KLKEQLHEREKYILELEMKLNDTHRELDTLKID--HQAVWANQDLLREQTNEIASFRREL 194 K+K++L E + +LE ++ E+ TLK +++ + L + + ++L Sbjct: 892 KIKKELEEEIERRQQLENEVKSAQEEIQTLKDQGPQESLVRKEVLKKVPDPALEESFQQL 951 Query: 195 DNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQ 374 + AE QH Q+ LQE L + + ALE++ R + K E LR R Q Sbjct: 952 QQTLAEE-QHKNQL--LQEELGALQLRLQALEQETRDGGQEYVVK-EVLRIEP---DRAQ 1004 Query: 375 EMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDRTGEQ 554 E ++LQ LRE + + + + + +QQ + L E ++++ E+ Sbjct: 1005 EDEVLQ-------LREELEALRRQKGAREAEVLLLQQ----RVAALAAEKSRVQEKVTER 1053 Query: 555 DVSQAAQDGSAESSY 599 +V + D E+ Y Sbjct: 1054 EVVKLQNDPQLEAEY 1068
>CP135_HUMAN (Q66GS9) Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal| protein 4) Length = 1140 Score = 35.4 bits (80), Expect = 0.15 Identities = 32/153 (20%), Positives = 62/153 (40%), Gaps = 13/153 (8%) Frame = +3 Query: 12 AAEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWAN----QDLLREQTNEIAS 179 + +LKE L R++ I L +L+ H+ELD + + + QD L E Sbjct: 777 SVNQLKETLVNRDREINSLRRQLDAAHKELDEVGRSREIAFKENRRLQDDLATMARENQE 836 Query: 180 FRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAW 359 EL+ + E+ + ++H + ES A E++++ D + D W Sbjct: 837 ISLELEAAVQEKEEMKSRVHKYITEVSRWESLMAAKEKENQDLLDRFQMLHNRAED---W 893 Query: 360 ITRVQE---------MDILQSQSLQAELRERTD 431 + + +++L + + LRER + Sbjct: 894 EVKAHQAEGESSSVRLELLSIDTERRHLRERVE 926
>NONO_PONPY (Q5RFL9) Non-POU domain-containing octamer-binding protein (NonO| protein) Length = 471 Score = 35.4 bits (80), Expect = 0.15 Identities = 28/99 (28%), Positives = 46/99 (46%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELD 197 E K+Q + ++ I E KL E++ + +HQ + QDL+R Q E EL Sbjct: 276 EMEKQQQDQVDRNIKEAREKLE---MEMEAARHEHQVMLMRQDLMRRQ--EELRRMEELH 330 Query: 198 NSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQD 314 N E ++ + L ++ +E R +E EE R Q+ Sbjct: 331 NQEVQKRKQL-ELRQEEERRRREEEMRRQQEEMMRRQQE 368
>NONO_HUMAN (Q15233) Non-POU domain-containing octamer-binding protein (NonO| protein) (54 kDa nuclear RNA- and DNA-binding protein) (p54(nrb)) (p54nrb) (55 kDa nuclear protein) (NMT55) (DNA-binding p52/p100 complex, 52 kDa subunit) Length = 471 Score = 35.4 bits (80), Expect = 0.15 Identities = 28/99 (28%), Positives = 46/99 (46%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELD 197 E K+Q + ++ I E KL E++ + +HQ + QDL+R Q E EL Sbjct: 276 EMEKQQQDQVDRNIKEAREKLE---MEMEAARHEHQVMLMRQDLMRRQ--EELRRMEELH 330 Query: 198 NSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQD 314 N E ++ + L ++ +E R +E EE R Q+ Sbjct: 331 NQEVQKRKQL-ELRQEEERRRREEEMRRQQEEMMRRQQE 368
>INVO_HUMAN (P07476) Involucrin| Length = 585 Score = 35.4 bits (80), Expect = 0.15 Identities = 44/207 (21%), Positives = 87/207 (42%), Gaps = 25/207 (12%) Frame = +3 Query: 21 KLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDN 200 +L EQ + K++ E +L ++ LK Q + L +++ EL Sbjct: 254 ELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQP------ELPE 307 Query: 201 SEAERAQHLKQIHDLQEHLREKESQYLALEEQ-----HRVAQDNIL----YKDEQLRDAH 353 + + +HL+Q +HL ++E Q LEEQ H Q+ L +++ QL Sbjct: 308 QQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPE 367 Query: 354 AWITRVQEMDILQSQ-----SLQAELRERTDQFGQCWATFQQ-----------QYVEMQQ 485 + ++++++ Q Q + +L+ Q GQ QQ +++E Q Sbjct: 368 QQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQV 427 Query: 486 GFLHTIQRLQLELIELRDRTGEQDVSQ 566 G L ++ + +L L + G+ +V + Sbjct: 428 GQLKHLEEQEGQLKHLEQQQGQLEVPE 454
>SKI_CHICK (P49140) Ski oncogene (C-ski)| Length = 750 Score = 35.4 bits (80), Expect = 0.15 Identities = 25/93 (26%), Positives = 47/93 (50%), Gaps = 7/93 (7%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLN-------DTHRELDTLKIDHQAVWANQDLLREQTNEIA 176 E ++ LHE K ++ E KLN H+EL+ L++ A ++ LRE T Sbjct: 579 EAKEKFLHEVVKMRVKQEEKLNAALQAKRSLHQELEFLRV------AKKEKLREATEAKR 632 Query: 177 SFRRELDNSEAERAQHLKQIHDLQEHLREKESQ 275 + R+E++ AE + +K+ ++ + L+ + Q Sbjct: 633 NLRKEIERLRAENEKKMKEANESRIRLKRELEQ 665
>M4K4_MOUSE (P97820) Mitogen-activated protein kinase kinase kinase kinase 4| (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase) Length = 1233 Score = 35.4 bits (80), Expect = 0.15 Identities = 33/130 (25%), Positives = 61/130 (46%), Gaps = 1/130 (0%) Frame = +3 Query: 27 KEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDNSE 206 ++QL E+E+Y +L L + + ++ K + L EQ RR+ + + Sbjct: 377 EQQLREQEEYKRQL---LAERQKRIEQQKEQRRR-------LEEQQRREREARRQQEREQ 426 Query: 207 AERAQHLK-QIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQEMD 383 R Q K ++ +L+ +E+E + A EE+ RV ++ Y QL + + ++ Sbjct: 427 RRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQ-EYIRRQLEEEQ------RHLE 479 Query: 384 ILQSQSLQAE 413 ILQ Q LQ + Sbjct: 480 ILQQQLLQEQ 489
>NONO_RAT (Q5FVM4) Non-POU domain-containing octamer-binding protein (NonO| protein) Length = 476 Score = 35.4 bits (80), Expect = 0.15 Identities = 28/99 (28%), Positives = 46/99 (46%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELD 197 E K+Q + ++ I E KL E++ + +HQ + QDL+R Q E EL Sbjct: 281 EMEKQQQDQVDRNIKEAREKLE---MEMEAARHEHQVMLMRQDLMRRQ--EELRRMEELH 335 Query: 198 NSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQD 314 N E ++ + L ++ +E R +E EE R Q+ Sbjct: 336 NQEVQKRKQL-ELRQEEERRRREEEMRRQQEEMMRRQQE 373
>MD1L1_CRIGR (Q80YF0) Mitotic spindle assembly checkpoint protein MAD1 (Mitotic| arrest deficient-like protein 1) (MAD1-like 1) Length = 717 Score = 35.4 bits (80), Expect = 0.15 Identities = 25/134 (18%), Positives = 68/134 (50%), Gaps = 2/134 (1%) Frame = +3 Query: 27 KEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDNSE 206 +E + + + E+++ D ++ L+ + Q + +L + + E + +EL S+ Sbjct: 156 RETISSLKGRVSEMQLNAMDQKVQVKRLESEKQELKEQLELQQRKCQEASQKIQELQASQ 215 Query: 207 AERAQHLKQIHDLQEH--LREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQEM 380 ERA H ++I DL++ L+E+++ + + + + + ++LR+ + + ++E Sbjct: 216 EERADHEQKIKDLEQKLCLQEQDAAVVKNMKSELLRLPRMERELKRLREENTHLREMKET 275 Query: 381 DILQSQSLQAELRE 422 + L ++ L+ R+ Sbjct: 276 NGLLTEELEGLQRK 289 Score = 33.9 bits (76), Expect = 0.43 Identities = 35/156 (22%), Positives = 70/156 (44%), Gaps = 17/156 (10%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELD 197 E+ EQ+ + Y++++E RE +++ H+ A +L R ++ RE+D Sbjct: 52 EERAEQIRSKS-YLIQME-------REKMQMELSHKR--ARVELERAANTSARNYEREVD 101 Query: 198 NSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWIT---- 365 ++ + L +I LQE E + E+HR+ + ++ +QLR+ + Sbjct: 102 RNQ----ELLARIRQLQEREAAAEEKMQEQLERHRLCKQSLDAASQQLREREDGLAAARE 157 Query: 366 -------RVQEMDI------LQSQSLQAELRERTDQ 434 RV EM + +Q + L++E +E +Q Sbjct: 158 TISSLKGRVSEMQLNAMDQKVQVKRLESEKQELKEQ 193
>RAD50_SULAC (O33600) DNA double-strand break repair rad50 ATPase| Length = 886 Score = 35.4 bits (80), Expect = 0.15 Identities = 30/150 (20%), Positives = 73/150 (48%), Gaps = 7/150 (4%) Frame = +3 Query: 15 AEKLKEQLHEREKYI-LELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIAS-FRR 188 A +LK+ + ++Y +E E+K D +RE +++ D L+ Q N + + +R Sbjct: 261 ALRLKDFEEKEKRYNKIETEVKELDENREKINTISSFKSILVQIDSLKSQINVVENDLKR 320 Query: 189 ELDNSEA-----ERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAH 353 + + + E+ + ++I ++ L EKE QY +E++ NI + + Sbjct: 321 KKEKLKRKKELEEKEKQYEEIEKRKKELEEKEKQYEEIEKRLTYVLKNIERQKNE----- 375 Query: 354 AWITRVQEMDILQSQSLQAELRERTDQFGQ 443 +++++ + +Q L+ ++++ +D+ Q Sbjct: 376 -----IEKLNYVDTQDLENKIKDVSDRINQ 400
>GAS8_DROME (Q8MT08) Growth-arrest-specific protein 8 homolog| Length = 479 Score = 35.0 bits (79), Expect = 0.19 Identities = 28/142 (19%), Positives = 59/142 (41%), Gaps = 16/142 (11%) Frame = +3 Query: 48 EKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDNSEAERAQHL 227 E + L L+ +++ E + +++ + ++ R+Q +E + + + E E Q L Sbjct: 32 EAFALRLKAEMDREREERNYFQLERDKIRTFWEITRQQLDE-TRYELQQKDKEIEATQDL 90 Query: 228 KQI----------------HDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAW 359 I H+ +R + L L ++H V Q+N L +D+ R Sbjct: 91 ADIDTKHVMQQMKHLQFENHNRLGEVRAEAMTQLKLAQEHHVLQENELQRDK--RQLRRM 148 Query: 360 ITRVQEMDILQSQSLQAELRER 425 + EM +Q + ++A E+ Sbjct: 149 LRERMEMSEMQLRQMEAHFNEK 170
>MYO5A_RAT (Q9QYF3) Myosin-5A (Myosin Va) (Dilute myosin heavy chain,| non-muscle) Length = 1828 Score = 35.0 bits (79), Expect = 0.19 Identities = 29/124 (23%), Positives = 57/124 (45%), Gaps = 7/124 (5%) Frame = +3 Query: 93 RELDTLKIDHQAVWANQDLLREQTNEIASFRRELDNSEAERAQHLKQIHDLQ-------E 251 REL LKI+ ++V + L N+I +R++D + ++++ +L+ E Sbjct: 903 RELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLMEKLTNLEGVYNSETE 962 Query: 252 HLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQEMDILQSQSLQAELRERTD 431 LR + EE+ +VA +L E++ D+ Q++S + + ER D Sbjct: 963 KLRNDVERLQLSEEEAKVATGRVLSLQEEIAKL--------RKDLEQTRSEKKSIEERAD 1014 Query: 432 QFGQ 443 ++ Q Sbjct: 1015 KYKQ 1018
>STMN3_CHICK (O93388) Stathmin-3 (SCG10-like protein) (Neuroplasticin-2)| Length = 180 Score = 35.0 bits (79), Expect = 0.19 Identities = 30/98 (30%), Positives = 53/98 (54%), Gaps = 10/98 (10%) Frame = +3 Query: 171 IASFRRELDNSEAER----AQHLKQIHDLQEHLREKESQYLALEEQH---RVAQDNILYK 329 + +R L+ +E R AQ LKQ+ + +EH E+E + ALEE + R+A++ + YK Sbjct: 82 LEELQRRLEAAEERRKTQEAQVLKQLAEKREH--EREVLHKALEENNNFSRLAEEKLNYK 139 Query: 330 DE---QLRDAHAWITRVQEMDILQSQSLQAELRERTDQ 434 E ++R+AH R + + + + AE+R +Q Sbjct: 140 MELSREIREAHLAALRER---LREKELHAAEVRRNKEQ 174
>ATK3_ARATH (P46875) Kinesin-3 (Kinesin-like protein C)| Length = 754 Score = 35.0 bits (79), Expect = 0.19 Identities = 47/197 (23%), Positives = 91/197 (46%), Gaps = 23/197 (11%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHREL----DTLKIDHQAVWANQDLLREQTNEIAS-- 179 EKLK L EK+ +++E+ L + EL + L+ + ++V L REQT ++A+ Sbjct: 97 EKLKNALELNEKHCVDMEVSLKNKEEELNMIIEELRKNFESV--QVQLAREQTEKLAAND 154 Query: 180 -------FRRELDNSEAERAQHL-KQIHDLQ---EHLREKESQYLALEEQHRVAQDNILY 326 R ++ ++A + L K DLQ + ++ Y L+E + Q LY Sbjct: 155 SLGKEKEARLSVEKAQAGLTEELGKAQGDLQTANQRIQSVNDMYKLLQEYNSSLQ---LY 211 Query: 327 KDE---QLRDAHAWITRVQE---MDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQG 488 + L +AH I R ++ I +L+ + +Q A+ Q+ ++ + Sbjct: 212 NSKLQGDLDEAHETIKRGEKERTAIIENIGNLKGQFSALQEQLAASKAS-QEDIMKQKGE 270 Query: 489 FLHTIQRLQLELIELRD 539 ++ I L++EL +++D Sbjct: 271 LVNEIASLKVELQQVKD 287 Score = 30.4 bits (67), Expect = 4.8 Identities = 19/83 (22%), Positives = 43/83 (51%), Gaps = 13/83 (15%) Frame = +3 Query: 135 ANQDLLREQ---TNEIASFRRELDNSEAERAQHLKQI----------HDLQEHLREKESQ 275 + +D+++++ NEIAS + EL + +R +HL ++ +D ++ + E E+ Sbjct: 260 SQEDIMKQKGELVNEIASLKVELQQVKDDRDRHLVEVKTLQTEATKYNDFKDAITELETT 319 Query: 276 YLALEEQHRVAQDNILYKDEQLR 344 + Q R QD ++ + +L+ Sbjct: 320 CSSQSTQIRQLQDRLVNSERRLQ 342
>HRP65_CHITE (Q9U1N0) Hrp65 protein (Ct-Hrp65)| Length = 535 Score = 35.0 bits (79), Expect = 0.19 Identities = 27/81 (33%), Positives = 41/81 (50%), Gaps = 3/81 (3%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKI-DHQAVWANQD--LLREQTNEIASFRR 188 E L+EQL +RE+ + + D R+ D +I D Q + QD +R Q + RR Sbjct: 350 ESLREQLRKREQDRDRQKKEWEDRERQADESRIRDEQQMRRQQDDMQMRMQRQDEEMRRR 409 Query: 189 ELDNSEAERAQHLKQIHDLQE 251 + +NS +AQ L + D QE Sbjct: 410 QQENSLFMQAQQLSNMLDQQE 430
>ATG11_MAGGR (Q51UJ9) Autophagy-related protein 11| Length = 1407 Score = 35.0 bits (79), Expect = 0.19 Identities = 41/163 (25%), Positives = 71/163 (43%), Gaps = 1/163 (0%) Frame = +3 Query: 24 LKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDNS 203 L+EQ E + + LE +L D ++LD L+ + + S R L+ Sbjct: 894 LREQCDEHKAKVNALEGELADGRKQLDELRTQ----------IAQGETGSESLRTRLEEE 943 Query: 204 EAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQEMD 383 E K+I L E L K+SQ +LEE+ R+ Q E+L+D+ + +T + Sbjct: 944 E-------KKIVRLTEDLASKQSQVGSLEEELRLFQ-------ERLQDSQSKLTTL---- 985 Query: 384 ILQSQSLQAELR-ERTDQFGQCWATFQQQYVEMQQGFLHTIQR 509 +L+ E R ERT Q + ++ V + + ++ R Sbjct: 986 -----TLRTETRNERTKDISQRLYSQNERLVRLLERLGFSVSR 1023
>UACA_CANFA (Q9GL21) Uveal autoantigen with coiled-coil domains and ankyrin| repeats protein Length = 1415 Score = 35.0 bits (79), Expect = 0.19 Identities = 36/185 (19%), Positives = 76/185 (41%), Gaps = 1/185 (0%) Frame = +3 Query: 9 VAAEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRR 188 V EK + + E K+ +T RE + + EI RR Sbjct: 626 VPTEKFESMKSLLSSEVNEKVKKIGETEREYE-----------------KSLTEIRQLRR 668 Query: 189 ELDNSEAERAQHLK-QIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWIT 365 EL+N +A+ AQH+K + H+ + E+ + LA + +++ +L +D Sbjct: 669 ELENCKAKLAQHVKPEEHEQLKSRLEQRAGELAKKVTELTSKNQVLQRD----------- 717 Query: 366 RVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDRT 545 E L ++ L ++ T + + Q EM++ T++ L+ +L+++ + Sbjct: 718 --VEKVYLDNKLLNQQVHNLTSEIKSHYVPLQVS-EEMKKSHDVTVEELKKQLLDVTQKC 774 Query: 546 GEQDV 560 ++ + Sbjct: 775 ADKQL 779
>MINK1_MOUSE (Q9JM52) Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated| protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK) Length = 1308 Score = 35.0 bits (79), Expect = 0.19 Identities = 35/143 (24%), Positives = 68/143 (47%), Gaps = 6/143 (4%) Frame = +3 Query: 15 AEKLKEQLHEREKYILELEMK--LNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRR 188 A K ++QL ++++ E +K L+ R ++ K + + V Q REQ R Sbjct: 368 ALKQQQQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRREREQ--------R 419 Query: 189 ELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDE----QLRDAHA 356 +L E +R ++ D+Q RE+E + E++++ Q + E QL+ HA Sbjct: 420 KLQEKEQQR-----RLEDMQALRREEERRQAEREQEYKRKQLEEQRQSERLQRQLQQEHA 474 Query: 357 WITRVQEMDILQSQSLQAELRER 425 ++ +Q+ Q Q LQ + +++ Sbjct: 475 YLKSLQQQQ--QQQQLQKQQQQQ 495
>KTN1_HUMAN (Q86UP2) Kinectin (Kinesin receptor) (CG-1 antigen)| Length = 1357 Score = 35.0 bits (79), Expect = 0.19 Identities = 48/210 (22%), Positives = 83/210 (39%), Gaps = 30/210 (14%) Frame = +3 Query: 3 HVVAAEKLKEQLHEREKYILELEMKLNDT-------HRELDTLKIDHQAVWANQDLLREQ 161 H A + L+ + +E + L KL DT + L L Q ++ L+ Q Sbjct: 511 HEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQ 570 Query: 162 TNEIASFRRELDNSEAERAQHLKQIH--------------DLQEHLREKESQYLALEEQH 299 +I L+ +EA +AQ ++Q H +L + + EK+ Q E+ Sbjct: 571 VQDI------LEQNEALKAQ-IQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSL 623 Query: 300 RVAQDNILYKDEQLRDAHAWITRVQEMDIL---QSQSLQAELRERTDQFGQCWATFQQQY 470 +D + K+E+L+D +Q M+ L + Q LQA E+ + Q Y Sbjct: 624 ASERDRLTSKEEELKD-------IQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVY 676 Query: 471 VE------MQQGFLHTIQRLQLELIELRDR 542 V+ +++ H I E L D+ Sbjct: 677 VKDDKIRLLEEQLQHEISNKMEEFKILNDQ 706 Score = 30.0 bits (66), Expect = 6.2 Identities = 24/106 (22%), Positives = 47/106 (44%), Gaps = 14/106 (13%) Frame = +3 Query: 24 LKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWAN--------------QDLLREQ 161 +K L E+EK + L D E ++LK Q V + + +L+E+ Sbjct: 879 MKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEK 938 Query: 162 TNEIASFRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQH 299 NE+ L E++ + + + D+Q+ + +SQ L++Q+ Sbjct: 939 ENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQN 984
>SAS6_CAEEL (O62479) Spindle assembly abnormal protein 6| Length = 492 Score = 35.0 bits (79), Expect = 0.19 Identities = 27/149 (18%), Positives = 74/149 (49%), Gaps = 13/149 (8%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELD 197 EK E+L ++ E+ K + E++ +K + + + + L+ ++ +E+A +++ + Sbjct: 208 EKQVEKLSGVKEEFEEMSEKFKELEDEVELVKEERENI---RLLVEDKEDEVADLKQDTE 264 Query: 198 NSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNI-------------LYKDEQ 338 + + + ++ +++ + LRE++ + L++++ Q I L K +Q Sbjct: 265 SLQKQLEENQEELEIVGNMLREEQGKVDQLQKRNVAHQKEIGKLRAELGTAQRNLEKADQ 324 Query: 339 LRDAHAWITRVQEMDILQSQSLQAELRER 425 L ++ Q +D+ + L+A+L+E+ Sbjct: 325 LLKRNSQQQNQQSLDMRKLGELEADLKEK 353
>MINK1_HUMAN (Q8N4C8) Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated| protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK) Length = 1332 Score = 35.0 bits (79), Expect = 0.19 Identities = 35/143 (24%), Positives = 68/143 (47%), Gaps = 6/143 (4%) Frame = +3 Query: 15 AEKLKEQLHEREKYILELEMK--LNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRR 188 A K ++QL ++++ E +K L+ R ++ K + + V Q REQ R Sbjct: 368 ALKQQQQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRREREQ--------R 419 Query: 189 ELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDE----QLRDAHA 356 +L E +R ++ D+Q RE+E + E++++ Q + E QL+ HA Sbjct: 420 KLQEKEQQR-----RLEDMQALRREEERRQAEREQEYKRKQLEEQRQSERLQRQLQQEHA 474 Query: 357 WITRVQEMDILQSQSLQAELRER 425 ++ +Q+ Q Q LQ + +++ Sbjct: 475 YLKSLQQQQ--QQQQLQKQQQQQ 495
>GOGA5_MOUSE (Q9QYE6) Golgin subfamily A member 5 (Golgin-84) (Sumiko protein)| (Ret-II protein) Length = 729 Score = 35.0 bits (79), Expect = 0.19 Identities = 34/139 (24%), Positives = 59/139 (42%), Gaps = 1/139 (0%) Frame = +3 Query: 21 KLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDN 200 +L+E HE+E E++ + H+ L QD+ +Q +E S R +L + Sbjct: 465 ELEELRHEKEMQKEEIQKLMGQMHQLRSEL----------QDMEAQQVSEAESAREQLQD 514 Query: 201 SEAERAQHLKQIHDLQEHLREKESQYLALEEQ-HRVAQDNILYKDEQLRDAHAWITRVQE 377 + + A+ +L+ L + ++ +EE HR N L + R+ R Q Sbjct: 515 LQDQIAKQRTSKQELETELERMKQEFRYMEEDLHRT--KNTLQSRIKDREEEIQKLRNQL 572 Query: 378 MDILQSQSLQAELRERTDQ 434 + S S Q+EL R Q Sbjct: 573 TNKTLSNSSQSELESRLHQ 591
>MYH9_RAT (Q62812) Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle| myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A) Length = 1960 Score = 35.0 bits (79), Expect = 0.19 Identities = 34/137 (24%), Positives = 65/137 (47%), Gaps = 9/137 (6%) Frame = +3 Query: 39 HEREKYILELEM-KLNDTH----RELDTLKIDHQAVWANQDLLREQTN---EIASFRREL 194 HE E E E+ K+ + H L ++ + A + L+EQ E+ + EL Sbjct: 842 HEDELLAKEAELTKVREKHLAAENRLTEMETMQSQLMAEKLQLQEQLQAKTELCAEAEEL 901 Query: 195 DNSEAERAQHLKQI-HDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRV 371 + Q L++I HDL+ + E+E + L+ + + Q NI +EQL + + ++ Sbjct: 902 RARLTAKKQELEEICHDLEARVEEEEERCQYLQAEKKKMQQNIQELEEQLEEEESARQKL 961 Query: 372 QEMDILQSQSLQAELRE 422 Q L+ + +A+L++ Sbjct: 962 Q----LEKVTTEAKLKK 974
>MYH8_MOUSE (P13542) Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal)| (MyHC-perinatal) Length = 1937 Score = 35.0 bits (79), Expect = 0.19 Identities = 42/211 (19%), Positives = 84/211 (39%) Frame = +3 Query: 3 HVVAAEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASF 182 H + +L EQ+ ++ +LE + ++ E+D L +N + + + + Sbjct: 1199 HADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDLS-------SNAEAIAKAKGNLEKM 1251 Query: 183 RRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWI 362 R L++ +E L+ KE EEQ R+ + + +A + Sbjct: 1252 CRTLEDQVSE--------------LKSKE------EEQQRLINELTAQRARLQTEAGEYS 1291 Query: 363 TRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDR 542 ++ E D L SQ L + T Q + +++ + + H +Q + + LR++ Sbjct: 1292 RQLDEKDALVSQ-LSRSKQASTQQIEELKRQLEEE-TKAKNALAHALQSSRHDCDLLREQ 1349 Query: 543 TGEQDVSQAAQDGSAESSYVQSKGSSMACKW 635 E+ Q+G AE SK +S +W Sbjct: 1350 YEEE------QEGKAELQRALSKANSEVAQW 1374
>SKI_HUMAN (P12755) Ski oncogene (C-ski)| Length = 728 Score = 35.0 bits (79), Expect = 0.19 Identities = 22/86 (25%), Positives = 45/86 (52%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELD 197 E +K ++ + EK L+ K H+EL+ L++ A ++ LRE T + R+E++ Sbjct: 565 EVVKMRVKQEEKLSAALQAK-RSLHQELEFLRV------AKKEKLREATEAKRNLRKEIE 617 Query: 198 NSEAERAQHLKQIHDLQEHLREKESQ 275 AE + +K+ ++ + L+ + Q Sbjct: 618 RLRAENEKKMKEANESRLRLKRELEQ 643
>MYH9_MOUSE (Q8VDD5) Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle| myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A) Length = 1959 Score = 35.0 bits (79), Expect = 0.19 Identities = 34/137 (24%), Positives = 65/137 (47%), Gaps = 9/137 (6%) Frame = +3 Query: 39 HEREKYILELEM-KLNDTH----RELDTLKIDHQAVWANQDLLREQTN---EIASFRREL 194 HE E E E+ K+ + H L ++ + A + L+EQ E+ + EL Sbjct: 842 HEDELLAKEAELTKVREKHLAAENRLTEMETMQSQLMAEKLQLQEQLQAETELCAEAEEL 901 Query: 195 DNSEAERAQHLKQI-HDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRV 371 + Q L++I HDL+ + E+E + L+ + + Q NI +EQL + + ++ Sbjct: 902 RARLTAKKQELEEICHDLEARVEEEEERCQYLQAEKKKMQQNIQELEEQLEEEESARQKL 961 Query: 372 QEMDILQSQSLQAELRE 422 Q L+ + +A+L++ Sbjct: 962 Q----LEKVTTEAKLKK 974
>RAD50_SULTO (Q96YR5) DNA double-strand break repair rad50 ATPase| Length = 879 Score = 35.0 bits (79), Expect = 0.19 Identities = 26/134 (19%), Positives = 60/134 (44%), Gaps = 3/134 (2%) Frame = +3 Query: 6 VVAAEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFR 185 ++ + L++ +E E ++ E +L + REL+ L I ++ R++ +I Sbjct: 183 IIELQSLEKYKNESENQKIQKEKELENIKRELEDLNI-------KEEKERKKYEDIVKLN 235 Query: 186 RELDNSEAERAQHLKQIHDLQE---HLREKESQYLALEEQHRVAQDNILYKDEQLRDAHA 356 E + E + + ++ L++ LRE+ L E+ + +IL KD+ + + Sbjct: 236 EEEEKKEKRYVELISLLNKLKDDISELREEVKDENRLREEKEKLEKDILEKDKLIEEKEK 295 Query: 357 WITRVQEMDILQSQ 398 I ++ + Q + Sbjct: 296 IIEAQNKIKLAQEK 309
>MYO6_HUMAN (Q9UM54) Myosin-6 (Myosin VI)| Length = 1285 Score = 35.0 bits (79), Expect = 0.19 Identities = 36/189 (19%), Positives = 84/189 (44%), Gaps = 2/189 (1%) Frame = +3 Query: 24 LKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASF--RRELD 197 LK+ E K I LE+ ++ ++ + + + + D L + + E+ S +++ Sbjct: 860 LKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQ 919 Query: 198 NSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQE 377 EAER + +++ + + RE++ + EE+ R + + K +Q + R + Sbjct: 920 EEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEERK--KREDD 977 Query: 378 MDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDRTGEQD 557 +Q++ ++A+L + ++ Q QQ +E ++ R+ EL + D Sbjct: 978 EKRIQAE-VEAQLARQKEEESQ-----QQAVLEQERRDRELALRIAQSEAELISDEAQAD 1031 Query: 558 VSQAAQDGS 584 ++ DG+ Sbjct: 1032 LALRRNDGT 1040
>SPO15_SCHPO (Q10411) Sporulation-specific protein 15| Length = 1957 Score = 34.7 bits (78), Expect = 0.25 Identities = 28/125 (22%), Positives = 63/125 (50%), Gaps = 6/125 (4%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRE-----LDTLKIDHQAVWANQDLLREQTNEIASF 182 EK K +++E + L+ E++ ++ E L TL + +A A + L E N + + Sbjct: 523 EKKKHEVYESQLNELKGELQTEISNSEHLSSQLSTLAAEKEAAVATNNELSESKNSLQT- 581 Query: 183 RRELDNSEAER-AQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAW 359 L N+ E+ A+ + Q+ + +++ ++ + L E H+ ++N +QL+D + Sbjct: 582 ---LCNAFQEKLAKSVMQLKENEQNFSSLDTSFKKLNESHQELENNHQTITKQLKDTSSK 638 Query: 360 ITRVQ 374 + ++Q Sbjct: 639 LQQLQ 643
>MYO10_BOVIN (P79114) Myosin-10 (Myosin X)| Length = 2052 Score = 34.7 bits (78), Expect = 0.25 Identities = 37/119 (31%), Positives = 53/119 (44%), Gaps = 8/119 (6%) Frame = +3 Query: 15 AEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQ---DLLREQTNEIASFR 185 AE+ K + E EK E E + + R L+ + Q + L++++ A Sbjct: 817 AEEEKRKREEEEKRKREEEERERERERREAELRAQQEEAARKQRELEALQQESQRAAELS 876 Query: 186 RELD----NSEAERAQHL-KQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRD 347 REL+ N + E L K+I DLQ R KE Q L+L E L K +QLRD Sbjct: 877 RELEKQKENKQVEEILRLEKEIEDLQ---RMKERQELSLTEAS-------LQKLQQLRD 925
>M21_STRPY (P50468) M protein, serotype 2.1 precursor| Length = 407 Score = 34.7 bits (78), Expect = 0.25 Identities = 31/124 (25%), Positives = 55/124 (44%), Gaps = 4/124 (3%) Frame = +3 Query: 126 AVWANQDLLREQTNEIASFRRELDNSEAERAQHLKQIHDLQEHLREK----ESQYLALEE 293 A +ANQ ++ + ++E SEAE +K + + + L EK E ++ +EE Sbjct: 31 AGFANQTTVKANSKNPVPVKKEAKLSEAELHDKIKNLEEEKAELFEKLDKVEEEHKKVEE 90 Query: 294 QHRVAQDNILYKDEQLRDAHAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYV 473 +H+ + + K E + + H QE Q + E ER Q + +Q+Q Sbjct: 91 EHKKDHEKLEKKSEDV-ERHYLRQLDQEYKEQQERQKNLEELERQSQ-REVEKRYQEQLQ 148 Query: 474 EMQQ 485 + QQ Sbjct: 149 KQQQ 152
>K0552_HUMAN (O60299) Protein KIAA0552| Length = 673 Score = 34.7 bits (78), Expect = 0.25 Identities = 31/117 (26%), Positives = 56/117 (47%), Gaps = 5/117 (4%) Frame = +3 Query: 6 VVAAEKLKEQLHEREKYIL----ELEMKLNDTHRE-LDTLKIDHQAVWANQDLLREQTNE 170 V+ ++ K+QL E ++ ELE K+ +E D L + W + ++ E Sbjct: 393 VLRLQQDKKQLQEEAARLMRQREELEDKVAACQKEQADFLPRIEETKWE----VCQKAGE 448 Query: 171 IASFRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQL 341 I+ +++L +S+A+ +Q L +I L+ LRE + EEQ +D+ K L Sbjct: 449 ISLLKQQLKDSQADVSQKLSEIVGLRSQLREGRASLREKEEQLLSLRDSFSSKQASL 505
>NEMO_DROME (Q9GYV5) NF-kappa-B essential modulator (Inhibitor of nuclear| factor kappa B kinase gamma subunit) (DmIKKgamma) (NEMO homolog) Length = 387 Score = 34.7 bits (78), Expect = 0.25 Identities = 27/109 (24%), Positives = 55/109 (50%), Gaps = 7/109 (6%) Frame = +3 Query: 237 HDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQEMD-----ILQSQS 401 H +EH++E ++Q L +++ + ++ K EQ+ H R++E D + + QS Sbjct: 154 HQYKEHVKECQAQIAILRVENQELKRDLETKIEQIEGVHT--IRLKEQDELRKSVSEKQS 211 Query: 402 LQAELRERTDQFGQCWATFQ--QQYVEMQQGFLHTIQRLQLELIELRDR 542 L +R D+ Q +F+ +Y + I+++QL++ EL+ R Sbjct: 212 LIDNMRVEIDKLKQLNHSFEFVPEYATESKS-QELIKKMQLDINELKAR 259
>GOGA5_HUMAN (Q8TBA6) Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5| protein) (Ret-II protein) Length = 731 Score = 34.7 bits (78), Expect = 0.25 Identities = 34/142 (23%), Positives = 58/142 (40%), Gaps = 4/142 (2%) Frame = +3 Query: 21 KLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDN 200 +L+E HE+E E++ + H+ L QD+ +Q NE S R +L + Sbjct: 467 ELEELRHEKEMQREEIQKLMGQIHQLRSEL----------QDMEAQQVNEAESAREQLQD 516 Query: 201 SEAERAQHLKQIHDLQEHLREKESQYLALEEQ----HRVAQDNILYKDEQLRDAHAWITR 368 + A +L+ L + ++ +EE Q I +DE+++ R Sbjct: 517 LHDQIAGQKASKQELETELERLKQEFHYIEEDLYRTKNTLQSRIKDRDEEIQK-----LR 571 Query: 369 VQEMDILQSQSLQAELRERTDQ 434 Q + S S Q+EL R Q Sbjct: 572 NQLTNKTLSNSSQSELENRLHQ 593
>CCD27_MOUSE (Q3V036) Coiled-coil domain-containing protein 27| Length = 639 Score = 34.7 bits (78), Expect = 0.25 Identities = 37/164 (22%), Positives = 74/164 (45%), Gaps = 22/164 (13%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDT-----HREL------DTLKIDHQAVWANQDLLREQT 164 E L+++L ER++ I ++ K ++ H+E+ + L + Q DL+ + Sbjct: 448 ELLEKELRERKQQIQDMTDKFSNLREEKKHQEIMGLIEKENLVLRQQVADLKMDLISSER 507 Query: 165 N--EIASFRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQ 338 E+ + +EL++ HL++ DL + L+ + E+Q RV + + E+ Sbjct: 508 TIKELNTQTKELEDQVNTDKDHLRRWKDLHDDLQTRNEIIQQTEQQTRVVLEATQARYEK 567 Query: 339 LRDAHAWI------TRVQEMDILQS---QSLQAELRERTDQFGQ 443 LR+ + M++ S +SLQ + ER+D + Q Sbjct: 568 LRNKIIQAVFSVSGNKNLSMELSDSYILESLQRIISERSDFYSQ 611
>NUF1_YEAST (P32380) Protein NUF1 (Spindle poly body spacer protein SPC110)| Length = 944 Score = 34.7 bits (78), Expect = 0.25 Identities = 37/174 (21%), Positives = 80/174 (45%), Gaps = 3/174 (1%) Frame = +3 Query: 45 REKYILELEMKLNDTHRELDTLKIDHQAV-WANQDLLREQT--NEIASFRRELDNSEAER 215 +E+ + E +MK R L++ + + + +AN D+ ++ NEI S + E+ E+ Sbjct: 120 KEQEVREHQMKKERFDRALESKLLGKRHITYANSDISNKELYINEIKSLKHEIKELRKEK 179 Query: 216 AQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQEMDILQS 395 L L+E + +++ ALE++ + N + ++ D I ++M+ + Sbjct: 180 NDTLNNYDTLEEETDDLKNRLQALEKE--LDAKNKIVNSRKVDDHSGCIEEREQME-RKL 236 Query: 396 QSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDRTGEQD 557 L+ +L+ DQ + Q ++++ ++ L EL EL+ E+D Sbjct: 237 AELERKLKTVKDQVLELENNSDVQSLKLRSK-EDELKNLMNELNELKSNAEEKD 289
>TPM_MIMNO (Q9GZ69) Tropomyosin| Length = 284 Score = 34.7 bits (78), Expect = 0.25 Identities = 39/174 (22%), Positives = 78/174 (44%), Gaps = 1/174 (0%) Frame = +3 Query: 15 AEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRREL 194 AE+++++L + E +LE + N+ ++L A N D + EQ E + +L Sbjct: 22 AEQMEQKLKDTETAKAKLEEEFNELQKKLT-------ATENNYDTVNEQLQEANT---KL 71 Query: 195 DNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDA-HAWITRV 371 +NSE KQI L+ + + + LEE + +++ + E+L +A A Sbjct: 72 ENSE-------KQITQLESDVGGLQRRLTLLEEDYERSEEKLNSTTEKLEEASKAADESE 124 Query: 372 QEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIEL 533 + +L+ +S E ER D+ + T + + F ++L + ++L Sbjct: 125 RNRKVLEGRSNSYE--ERIDELEKQLETAKNVATDADHKFDEAARKLAITEVDL 176
>SAS6_CHICK (Q5ZMV2) Spindle assembly abnormal protein 6 homolog| Length = 640 Score = 34.7 bits (78), Expect = 0.25 Identities = 33/168 (19%), Positives = 80/168 (47%), Gaps = 4/168 (2%) Frame = +3 Query: 24 LKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRE---- 191 L + HE+EK+I +L+ ++ +E+ ++D L +T E+ +E Sbjct: 311 LDAECHEKEKFINQLQTRVAVLEQEI-----------KDKDQLVIRTKEVLDATQEQKVI 359 Query: 192 LDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRV 371 L+ + ++ H+++ L+ ++ ++ L E + Q+++ +L+ + + Sbjct: 360 LEENTEKKQSHIEK---LETTIKSLSAELLKANEIIKKLQEDLKTLMSKLKLKNTVTIQQ 416 Query: 372 QEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQ 515 +++ + + LQ E RE + GQ +Q+ ++Q+ TIQ+L+ Sbjct: 417 EKLLAEKEERLQKEQRE-LQETGQSLRMKEQEVCKLQEQLETTIQKLE 463
>ACPH_ECOL6 (Q8FKC6) Acyl carrier protein phosphodiesterase (EC 3.1.4.14) (ACP| phosphodiesterase) Length = 193 Score = 34.7 bits (78), Expect = 0.25 Identities = 33/147 (22%), Positives = 58/147 (39%), Gaps = 6/147 (4%) Frame = +3 Query: 90 HRELDTLKIDHQAVWANQDLLREQTNEIASFRREL--DNSEAERAQHLKQIHDLQE---H 254 HR +D L + V ++ R +T +A ++ D+ + L LQE + Sbjct: 45 HRRIDVLTDNLPEVREAREWFRNETRRVAPITLDVMWDHFLSRHWSQLSPDFPLQEFTCY 104 Query: 255 LREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQEMDILQS-QSLQAELRERTD 431 RE+ L Q + +N L+ ++ W+ R ++MD +QS + A R R D Sbjct: 105 AREQVMTILPDSPQRFINLNNYLWSEQ-------WLVRYRDMDFIQSVLNGMASRRPRLD 157 Query: 432 QFGQCWATFQQQYVEMQQGFLHTIQRL 512 W Y ++ F R+ Sbjct: 158 ALRDSWYDLDAHYDALETRFWQFYPRM 184
>VIME_HUMAN (P08670) Vimentin| Length = 465 Score = 34.7 bits (78), Expect = 0.25 Identities = 52/230 (22%), Positives = 96/230 (41%), Gaps = 34/230 (14%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQT----------- 164 E+LK Q R + E EM+ + R++D L D V +D L E Sbjct: 135 EQLKGQGKSRLGDLYEEEMR--ELRRQVDQLTNDKARVEVERDNLAEDIMRLREKLQEEM 192 Query: 165 -------NEIASFRRELDNSEAERAQHLKQIHDLQEH------LREKESQYL--ALEEQH 299 N + SFR+++DN+ R +++ LQE L E+E Q L ++EQH Sbjct: 193 LQREEAENTLQSFRQDVDNASLARLDLERKVESLQEEIAFLKKLHEEEIQELQAQIQEQH 252 Query: 300 RVAQDNILYKD--EQLRDAHAWITRVQEMDILQSQ----SLQAELRERTDQFGQCWATFQ 461 ++ D LRD V ++ +++ S A+L E ++ + Sbjct: 253 VQIDVDVSKPDLTAALRDVRQQYESVAAKNLQEAEEWYKSKFADLSEAANRNNDALRQAK 312 Query: 462 QQYVEMQQGFLHTIQRLQLELIELR--DRTGEQDVSQAAQDGSAESSYVQ 605 Q+ E + +Q L E+ L+ + + E+ + + ++ + E++ Q Sbjct: 313 QESTE----YRRQVQSLTCEVDALKGTNESLERQMREMEENFAVEAANYQ 358
>TAXB1_PONPY (Q5R4U3) Tax1-binding protein 1 homolog| Length = 813 Score = 34.3 bits (77), Expect = 0.33 Identities = 37/139 (26%), Positives = 64/139 (46%), Gaps = 2/139 (1%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELD 197 +KLK+ HERE+ LE ++K +EL + + + + N L+ +E+ + + Sbjct: 257 DKLKKAQHEREQ--LECQLKTEKDEKELYKVHLKNTEI-ENTKLM----SEVQTLKNLDG 309 Query: 198 NSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWI--TRV 371 N E+ ++I LQ L EKE+ +D K EQLR A + TR Sbjct: 310 NKESVITHFKEEIGRLQLCLAEKENLQRTFLLTTSSKEDTFFLK-EQLRKAEEQVQATRQ 368 Query: 372 QEMDILQSQSLQAELRERT 428 + + + + S +R+RT Sbjct: 369 EVVFLAKELSDAVNVRDRT 387
>STMN3_MOUSE (O70166) Stathmin-3 (SCG10-like protein) (SCG10-related protein| HiAT3) (Hippocampus abundant transcript 3) Length = 180 Score = 34.3 bits (77), Expect = 0.33 Identities = 26/86 (30%), Positives = 48/86 (55%), Gaps = 6/86 (6%) Frame = +3 Query: 195 DNSEAERAQHLKQIHDLQEHLREKESQYLALEEQH---RVAQDNILYKDE---QLRDAHA 356 + + + AQ LKQ+ + +EH E+E + ALEE + R+A++ + YK E ++R+AH Sbjct: 94 ERRKTQEAQVLKQLAERREH--EREVLHKALEENNNFSRLAEEKLNYKMELSKEIREAHL 151 Query: 357 WITRVQEMDILQSQSLQAELRERTDQ 434 R + + + + AE+R +Q Sbjct: 152 AALRER---LREKELHAAEVRRNKEQ 174
>STMN2_RAT (P21818) Stathmin-2 (SCG10 protein) (Superior cervical ganglion-10| protein) Length = 179 Score = 34.3 bits (77), Expect = 0.33 Identities = 29/99 (29%), Positives = 55/99 (55%), Gaps = 17/99 (17%) Frame = +3 Query: 171 IASFRRELDNSEAER----AQHLKQIHDLQEHLREKESQYLALEEQH---RVAQDNILYK 329 + +++L+ +E R AQ LKQ+ + +EH E+E ALEE + ++A++ ++ K Sbjct: 81 LEEIQKKLEAAEGRRKSQEAQVLKQLAEKREH--EREVLQKALEENNNFSKMAEEKLILK 138 Query: 330 DEQLRDAH-----AWITRVQE-----MDILQSQSLQAEL 416 EQ+++ A I R+QE ++ +++ LQ EL Sbjct: 139 MEQIKENREANLAAIIERLQEKERHAAEVRRNKELQVEL 177
>STMN2_MOUSE (P55821) Stathmin-2 (SCG10 protein) (Superior cervical ganglion-10| protein) Length = 179 Score = 34.3 bits (77), Expect = 0.33 Identities = 26/87 (29%), Positives = 50/87 (57%), Gaps = 13/87 (14%) Frame = +3 Query: 195 DNSEAERAQHLKQIHDLQEHLREKESQYLALEEQH---RVAQDNILYKDEQLRDAH---- 353 + +++ AQ LKQ+ + +EH E+E ALEE + ++A++ ++ K EQ+++ Sbjct: 93 ERRKSQEAQVLKQLAEKREH--EREVLQKALEENNNFSKMAEEKLILKMEQIKENREANL 150 Query: 354 -AWITRVQE-----MDILQSQSLQAEL 416 A I R+QE ++ +++ LQ EL Sbjct: 151 AAIIERLQEKERHAAEVRRNKELQVEL 177
>STMN2_HUMAN (Q93045) Stathmin-2 (SCG10 protein) (Superior cervical ganglion-10| protein) Length = 179 Score = 34.3 bits (77), Expect = 0.33 Identities = 26/87 (29%), Positives = 50/87 (57%), Gaps = 13/87 (14%) Frame = +3 Query: 195 DNSEAERAQHLKQIHDLQEHLREKESQYLALEEQH---RVAQDNILYKDEQLRDAH---- 353 + +++ AQ LKQ+ + +EH E+E ALEE + ++A++ ++ K EQ+++ Sbjct: 93 ERRKSQEAQVLKQLAEKREH--EREVLQKALEENNNFSKMAEEKLILKMEQIKENREANL 150 Query: 354 -AWITRVQE-----MDILQSQSLQAEL 416 A I R+QE ++ +++ LQ EL Sbjct: 151 AAIIERLQEKERHAAEVRRNKELQVEL 177
>LIPA_CAEEL (Q21049) Liprin-alpha (LAR-interacting protein alpha) (Synapse| defective protein 2) Length = 1139 Score = 34.3 bits (77), Expect = 0.33 Identities = 46/211 (21%), Positives = 91/211 (43%), Gaps = 15/211 (7%) Frame = +3 Query: 24 LKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDN- 200 LKEQL E+++ I+EL+ + N+T L ++H ++ E++ + +R+ N Sbjct: 103 LKEQLLEKDEEIVELKAERNNTR-----LLLEHLECLVSR---HERSLRMTVMKRQAQNH 154 Query: 201 ----SEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITR 368 SE E + LK + + + L EK + E+ RVA + + +E+L + Sbjct: 155 AGVSSEVEVLKALKSLFEHHKALDEK------VRERLRVAMERVATLEEELSTKGDENSS 208 Query: 369 VQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLEL-------I 527 ++ + + + G + + +EMQ+ ++R++ EL Sbjct: 209 LKARIATYAAEAEEAMASNAPINGSISSESANRLIEMQE----ALERMKTELANSLKQST 264 Query: 528 ELRDRTGE---QDVSQAAQDGSAESSYVQSK 611 E+ R E Q A + +A+ S V+ K Sbjct: 265 EITTRNAELEDQLTEDAREKHAAQESIVRLK 295
>RBP24_HUMAN (Q4ZG46) Ran-binding protein 2-like 4 (RanBP2L4)| Length = 1583 Score = 34.3 bits (77), Expect = 0.33 Identities = 40/195 (20%), Positives = 86/195 (44%), Gaps = 23/195 (11%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELD 197 E L+++ E+E+ I ++++ +ELD+ + + Q V + LR + +++++ R+L Sbjct: 853 ENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEELESLRSEKDQLSASMRDLI 912 Query: 198 NS--------------------EAERAQHLK-QIHDLQEHLREK--ESQYLALEEQHRVA 308 E ERA + + +I DL LR + + + + + +A Sbjct: 913 QGAESYKNLLLEYEKQSEQLDVEKERANNFEHRIEDLTRQLRNSTLQCETINSDNEDLLA 972 Query: 309 QDNILYKDEQLRDAHAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQG 488 + L + +L + I VQ + + L+AE ++ + + AT + E+Q Sbjct: 973 RIETLQSNAKLLEVQ--ILEVQRAKAMVDKELEAEKLQKEQKIKE-HATTVNELEELQVQ 1029 Query: 489 FLHTIQRLQLELIEL 533 ++LQ + EL Sbjct: 1030 LQKQKKQLQKTMQEL 1044 Score = 30.0 bits (66), Expect = 6.2 Identities = 29/144 (20%), Positives = 65/144 (45%), Gaps = 6/144 (4%) Frame = +3 Query: 18 EKLKE------QLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIAS 179 +K+KE +L E + + + + +L T +EL+ +K D A Q L EIA Sbjct: 1011 QKIKEHATTVNELEELQVQLQKQKKQLQKTMQELELVKKD-----AQQTTLMNM--EIAD 1063 Query: 180 FRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAW 359 + R + + +I DL++ ++ ++ + L+E+ Q ++ +E+ Sbjct: 1064 YERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEK------- 1116 Query: 360 ITRVQEMDILQSQSLQAELRERTD 431 T+++++ + + L + TD Sbjct: 1117 NTKIKQLLVKTKKELADSKQAETD 1140
>ITSN2_MOUSE (Q9Z0R6) Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3| domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2) Length = 1658 Score = 34.3 bits (77), Expect = 0.33 Identities = 39/207 (18%), Positives = 85/207 (41%), Gaps = 8/207 (3%) Frame = +3 Query: 6 VVAAEKLKEQLHEREK---YILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIA 176 ++ ++L+++L E + Y++ + LN+ + + + E+ Sbjct: 534 IMEIKQLQQELKEYQNKLIYLVPEKQLLNERIKNMQLSNTPDSGISLLHKKSSEKEELCQ 593 Query: 177 SFRRELDNSEAERAQHLKQIHDLQEHLREKESQY----LALEEQHRVAQDNILYKDEQLR 344 + +LD E E A L ++ L+E Y LALE+ H++ +D + + Sbjct: 594 RLKEQLDALEKETASKLSEMDSFNNQLKELRESYNTQQLALEQLHKIKRDKLKEIER--- 650 Query: 345 DAHAWITRVQEMDILQSQSLQAELRERTDQFGQ-CWATFQQQYVEMQQGFLHTIQRLQLE 521 + ++ +Q + L+ E + Q + W ++ E +Q +RLQ E Sbjct: 651 ---------KRLEQIQKKKLEDEAARKAKQGKENLWRESIRKEEEEKQ------KRLQEE 695 Query: 522 LIELRDRTGEQDVSQAAQDGSAESSYV 602 + +D+T E++ A+ S+ V Sbjct: 696 --KSQDKTQEEERKAEAKQSETASALV 720
>GCC2_HUMAN (Q8IWJ2) GRIP and coiled-coil domain-containing protein 2 (Golgi| coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW-11) (NY-REN-53 antigen) Length = 1583 Score = 34.3 bits (77), Expect = 0.33 Identities = 40/195 (20%), Positives = 86/195 (44%), Gaps = 23/195 (11%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELD 197 E L+++ E+E+ I ++++ +ELD+ + + Q V + LR + +++++ R+L Sbjct: 853 ENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEELESLRSEKDQLSASMRDLI 912 Query: 198 NS--------------------EAERAQHLK-QIHDLQEHLREK--ESQYLALEEQHRVA 308 E ERA + + +I DL LR + + + + + +A Sbjct: 913 QGAESYKNLLLEYEKQSEQLDVEKERANNFEHRIEDLTRQLRNSTLQCETINSDNEDLLA 972 Query: 309 QDNILYKDEQLRDAHAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQG 488 + L + +L + I VQ + + L+AE ++ + + AT + E+Q Sbjct: 973 RIETLQSNAKLLEVQ--ILEVQRAKAMVDKELEAEKLQKEQKIKE-HATTVNELEELQVQ 1029 Query: 489 FLHTIQRLQLELIEL 533 ++LQ + EL Sbjct: 1030 LQKEKKQLQKTMQEL 1044 Score = 29.6 bits (65), Expect = 8.1 Identities = 29/144 (20%), Positives = 65/144 (45%), Gaps = 6/144 (4%) Frame = +3 Query: 18 EKLKE------QLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIAS 179 +K+KE +L E + + + + +L T +EL+ +K D A Q L EIA Sbjct: 1011 QKIKEHATTVNELEELQVQLQKEKKQLQKTMQELELVKKD-----AQQTTLMNM--EIAD 1063 Query: 180 FRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAW 359 + R + + +I DL++ ++ ++ + L+E+ Q ++ +E+ Sbjct: 1064 YERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEK------- 1116 Query: 360 ITRVQEMDILQSQSLQAELRERTD 431 T+++++ + + L + TD Sbjct: 1117 NTKIKQLLVKTKKELADSKQAETD 1140
>USO1_YEAST (P25386) Intracellular protein transport protein USO1 (Int-1)| Length = 1790 Score = 34.3 bits (77), Expect = 0.33 Identities = 38/182 (20%), Positives = 82/182 (45%), Gaps = 9/182 (4%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQ--------TNEI 173 E LKE+ + EK E + +LN L++L+ +H+ + A EQ EI Sbjct: 1120 EHLKEEKIQLEKEATETKQQLNSLRANLESLEKEHEDLAAQLKKYEEQIANKERQYNEEI 1179 Query: 174 ASFRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAH 353 + E+ +++ E K+ +L+ ++ +S EEQ + + I + Q+++ Sbjct: 1180 SQLNDEITSTQQENESIKKKNDELEGEVKAMKS---TSEEQSNLKKSEIDALNLQIKELK 1236 Query: 354 AWITRVQEMDILQS-QSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIE 530 E +L+S +S+++E + + +C F+++ V + L + + +E Sbjct: 1237 K-KNETNEASLLESIKSVESETVKIKELQDEC--NFKEKEVSELEDKLKASEDKNSKYLE 1293 Query: 531 LR 536 L+ Sbjct: 1294 LQ 1295 Score = 33.5 bits (75), Expect = 0.56 Identities = 48/210 (22%), Positives = 93/210 (44%), Gaps = 21/210 (10%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELD 197 EKLK ++ + + E E KL + T + + +L+R Q NE +E+D Sbjct: 1352 EKLKNEIQIKNQ-AFEKERKLLNEGSSTITQEYSEKINTLEDELIRLQ-NENELKAKEID 1409 Query: 198 NSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKD--------------- 332 N+ +E + + +D E L EK++ +L+++ +D I D Sbjct: 1410 NTRSE-LEKVSLSND--ELLEEKQNTIKSLQDEILSYKDKITRNDEKLLSIERDNKRDLE 1466 Query: 333 ---EQLRDAHAWITRVQE-MDILQSQSL--QAELRERTDQFGQCWATFQQQYVEMQQGFL 494 EQLR A +V+E + L+ +S +AEL + + + +T + E++ + Sbjct: 1467 SLKEQLRAAQESKAKVEEGLKKLEEESSKEKAELEKSKEMMKKLESTIESNETELKSS-M 1525 Query: 495 HTIQRLQLELIELRDRTGEQDVSQAAQDGS 584 TI++ E +E ++ E+D+ + S Sbjct: 1526 ETIRKSD-EKLEQSKKSAEEDIKNLQHEKS 1554
>PLEC1_CRIGR (Q9JI55) Plectin-1 (PLTN) (PCN) (300-kDa intermediate| filament-associated protein) (IFAP300) (Fragment) Length = 4473 Score = 34.3 bits (77), Expect = 0.33 Identities = 52/209 (24%), Positives = 86/209 (41%), Gaps = 22/209 (10%) Frame = +3 Query: 27 KEQLHEREKYI----LELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASF---- 182 K+ L +RE++I +LE D + L+ + Q + + +E+ +AS Sbjct: 2425 KDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQR--QQRQMEQEKQELVASMEEAR 2482 Query: 183 RRELDNSEA-----ERAQHLKQIHDLQEHLREKESQYLA-----LEEQHRVAQDNILYKD 332 RR+ + EA E QHL+ QE L +E+Q L LEE+HR A L Sbjct: 2483 RRQCEAEEAVRRKQEELQHLELQRQQQEKLLAEENQRLRERLQRLEEEHRAA----LAHS 2538 Query: 333 EQLRDAHAWITRV--QEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFL--HT 500 E++ A + D L S++ E + Q Q + + G L Sbjct: 2539 EEIAATQAAAAKALPNGRDALDGPSMEVEPEHAFEGLRQKVPALQLR----EAGILSAEE 2594 Query: 501 IQRLQLELIELRDRTGEQDVSQAAQDGSA 587 +QRL+ + + + +DV Q Q S+ Sbjct: 2595 LQRLEQGHTTVAELSQREDVRQYLQGRSS 2623
>YKF4_YEAST (P35732) Hypothetical 84.0 kDa protein in NUP120-CSE4 intergenic| region Length = 738 Score = 34.3 bits (77), Expect = 0.33 Identities = 35/196 (17%), Positives = 74/196 (37%), Gaps = 11/196 (5%) Frame = +3 Query: 57 ILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDN-----------S 203 + EL+ +++D ++ + + V + +EQ E A E ++ Sbjct: 265 VAELKKEISDIKKDDQKSEASEEKVNEQETSAQEQEEETAEPSEENEDRVPEVDGEEVQE 324 Query: 204 EAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQEMD 383 EAE+ + +K+ E L +++ A EE+ V ++ + V + Sbjct: 325 EAEKKEQVKEEEQTAEELEQEQDNVAAPEEEVTVVEEKVEISAVISEPPEDQANTVPQPQ 384 Query: 384 ILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDRTGEQDVS 563 Q Q + ++ Q Q Q Q + Q L Q+ Q + ++ + + E+ +S Sbjct: 385 QQSQQPQQPQQPQQPQQPQQPQQQQQPQQPQQPQQQLQQQQQQQQQPVQAQAQAQEEQLS 444 Query: 564 QAAQDGSAESSYVQSK 611 Q + Y Q + Sbjct: 445 QNYYTQQQQQQYAQQQ 460
>VIMB_CARAU (P48673) Vimentin beta| Length = 450 Score = 34.3 bits (77), Expect = 0.33 Identities = 46/211 (21%), Positives = 89/211 (42%), Gaps = 25/211 (11%) Frame = +3 Query: 48 EKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQT-----------NEIASFRREL 194 E + EL +++ E ++++D + N + LR++ N + SFR+++ Sbjct: 137 EDEMRELRRQVDQLINEKASVEVDRDNLGENIERLRQKLQEEMLQREDAENSLRSFRQDV 196 Query: 195 DNSEAERAQHLKQIHDLQEH------LREKESQYLALEEQHRVAQDNILYKDEQLRDAHA 356 DN+ R +++ LQE L ++E L ++ Q R Q ++ L A Sbjct: 197 DNASLARLDLERKVESLQEEIAFLKKLHDEELAELQMQIQERHVQIDMEVAKPDLTAALR 256 Query: 357 WITRVQEMDILQSQSLQAELRERTDQFGQC--WATFQQQYVEMQQ----GFLHTIQRLQL 518 + Q+ + L S++LQ +F AT + V + + + +Q L Sbjct: 257 DVR--QQYETLASRNLQESEEWYKSKFADLSEAATRNSEAVRLAKHEANDYRRQLQSLTC 314 Query: 519 ELIELRDRTG--EQDVSQAAQDGSAESSYVQ 605 +L LR G E+ + + + S E+S Q Sbjct: 315 DLEALRGTNGSLERQMREMEDNFSIEASGYQ 345
>MYSP_MYTGA (O96064) Paramyosin| Length = 864 Score = 34.3 bits (77), Expect = 0.33 Identities = 42/135 (31%), Positives = 61/135 (45%), Gaps = 18/135 (13%) Frame = +3 Query: 63 ELEMKLNDTHRELDTL-KIDHQAVWANQDLLRE----QTNEIASFRRE-----------L 194 E+E +L + E+D++ K +A+ Q L E EI+ +++ L Sbjct: 496 EMEQRLREKDEEIDSIRKSSARAIDELQRTLVEVETRYKTEISRIKKKYETDIRELEGAL 555 Query: 195 DNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQD--NILYKDEQLRDAHAWITR 368 DN+ A++LKQI LQ RE E L LEE R D N L E+ R IT Sbjct: 556 DNANRANAEYLKQIKSLQNRNRELE---LQLEEATRQLDDTRNQLSVSERKR-----ITI 607 Query: 369 VQEMDILQSQSLQAE 413 QE++ +S AE Sbjct: 608 QQELEDARSLLEHAE 622 Score = 33.5 bits (75), Expect = 0.56 Identities = 27/108 (25%), Positives = 49/108 (45%), Gaps = 11/108 (10%) Frame = +3 Query: 141 QDLLREQTNEIASFRRELD-------NSEAERAQHLKQIHDLQEHLREKESQ----YLAL 287 Q+ LRE NE+ + R ++ EAER + D +E LR+ E++ AL Sbjct: 431 QNALREANNELKAANRTINELTALKAQLEAERDNLASALRDTEEALRDAEAKLAAAQAAL 490 Query: 288 EEQHRVAQDNILYKDEQLRDAHAWITRVQEMDILQSQSLQAELRERTD 431 + + + KDE++ + + +D LQ ++ E R +T+ Sbjct: 491 NQLRSEMEQRLREKDEEIDSIRK--SSARAIDELQRTLVEVETRYKTE 536 Score = 33.1 bits (74), Expect = 0.73 Identities = 32/182 (17%), Positives = 73/182 (40%), Gaps = 4/182 (2%) Frame = +3 Query: 9 VAAEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRR 188 + + L ++ + E L+ + +D E L+ + + A L+ E+A Sbjct: 362 IIVQDLTKRNRQLENENAALQKRCDDLSAENGQLRNEKANLEAECARLKVANAELAEKNA 421 Query: 189 ELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYK----DEQLRDAHA 356 L+ A L++ ++ + ++ AL+ Q +DN+ +E LRDA A Sbjct: 422 NLERENAGLQNALREANNELKAANRTINELTALKAQLEAERDNLASALRDTEEALRDAEA 481 Query: 357 WITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELR 536 + Q ++ LRE+ ++ + + E+Q+ + R + E+ ++ Sbjct: 482 KLAAAQAALNQLRSEMEQRLREKDEEIDSIRKSSARAIDELQRTLVEVETRYKTEISRIK 541 Query: 537 DR 542 + Sbjct: 542 KK 543
>MYS3_HYDAT (P39922) Myosin heavy chain, clone 203 (Fragment)| Length = 539 Score = 34.3 bits (77), Expect = 0.33 Identities = 32/113 (28%), Positives = 50/113 (44%) Frame = +3 Query: 12 AAEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRE 191 A +K K +L E+EK L E LN+T LD +K N +L EQ NE+ S + Sbjct: 412 AMKKAKAKL-EKEKSALNNE--LNETKNSLDQIKKQKTNSDKNSRMLEEQINELNSKLAQ 468 Query: 192 LDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDA 350 +D ++ +++ L SQ E +A NI + QL ++ Sbjct: 469 VDELHSQSESKNSKVN---SELLALNSQLSESEHNLGIATKNIKTLESQLAES 518 Score = 33.1 bits (74), Expect = 0.73 Identities = 25/107 (23%), Positives = 46/107 (42%) Frame = +3 Query: 30 EQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDNSEA 209 E+L E +L LE K+ + ++D L E+T E+ S + E Sbjct: 127 EKLDGEEHSVLVLEEKIQEAEEKIDELT--------------EKTEELQS---NISRLET 169 Query: 210 ERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDA 350 E+ KQI L E +R+++ + + + + + + EQL+ A Sbjct: 170 EKQNRDKQIDTLNEDIRKQDETISKMNAEKKHVDEELKDRTEQLQAA 216
>ALM1_SCHPO (Q9UTK5) Abnormal long morphology protein 1 (Sp8)| Length = 1727 Score = 34.3 bits (77), Expect = 0.33 Identities = 46/213 (21%), Positives = 94/213 (44%), Gaps = 10/213 (4%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELD 197 + L+E L E+ I EL K+ +TLK D N++ L Q + ++L+ Sbjct: 1240 KSLRENLERNEEVITELREKI-------ETLKTDLANFRLNKEQLESQLQTEKAAVKKLE 1292 Query: 198 NSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYK-DEQLRDAHAWITRVQ 374 NS E +H ++I L + S + + V+++N++ + ++++ + + V+ Sbjct: 1293 NSNEEYKRHNQEIL-LSLNSSTSTSSDASRLKNELVSKENLIEELNQEIGHLKSELETVK 1351 Query: 375 ------EMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTI-QRLQLELIEL 533 E + Q+QS +L + + W T +Q V + I Q+L + EL Sbjct: 1352 SKSEDLENERAQNQSKIEQLELKNTKLAAAWRTKYEQVVNKSLEKHNQIRQQLSQKTSEL 1411 Query: 534 RDRTGE--QDVSQAAQDGSAESSYVQSKGSSMA 626 + E Q Q + + ++ QS+ S+++ Sbjct: 1412 EAKVAECHQLNEQLNKPSATPTATTQSEPSTVS 1444 Score = 31.6 bits (70), Expect = 2.1 Identities = 40/202 (19%), Positives = 83/202 (41%), Gaps = 5/202 (2%) Frame = +3 Query: 3 HVVAAEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASF 182 H +A + +++ ++ ELE E+ I NQDLL +E+ + Sbjct: 627 HNSSAGNIDDKMKSIDESTRELEKNYEVYRNEMTA--IQESLSKRNQDLL----SEMEAI 680 Query: 183 RRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWI 362 R+EL+NS+ ++ ++ + + + + L ++ QD I +D++ + Sbjct: 681 RKELENSKYQQQLSTDRLTNANNDVEAFKKEAKELRSINQNLQDIISRQDQRASKFAEEL 740 Query: 363 TRVQEM-----DILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELI 527 V + L + + +LR+RT Q++ + L +RL + Sbjct: 741 LHVNSLAERLKGELNASKGEKDLRKRT----------QERLISENDKLLAERERLMSLVS 790 Query: 528 ELRDRTGEQDVSQAAQDGSAES 593 +L+ +Q +S AA+ ES Sbjct: 791 DLQTFLNQQQLSDAARKVKFES 812 Score = 29.6 bits (65), Expect = 8.1 Identities = 30/115 (26%), Positives = 51/115 (44%), Gaps = 5/115 (4%) Frame = +3 Query: 12 AAEKLKEQLHEREK-----YILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIA 176 AA KL E++ ER K Y L+ L H ++ +L+ Q + QD EIA Sbjct: 947 AASKLAEEMVERVKTEYDEYRLQTSESLEKNHLKITSLE---QRIVILQD-------EIA 996 Query: 177 SFRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQL 341 S +N + + + + +HL + S + E+QH +++ YK + L Sbjct: 997 SSSLRCENITKDSETRVALLLEENKHLNNELSSHRNAEKQHLEKEND--YKQQLL 1049
>VIME_PANTR (Q5R1W8) Vimentin| Length = 465 Score = 34.3 bits (77), Expect = 0.33 Identities = 34/120 (28%), Positives = 52/120 (43%), Gaps = 26/120 (21%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQT----------- 164 E+LK Q R + E EM+ + R++D L D V +D L E Sbjct: 135 EQLKGQGKSRLGDLYEEEMR--ELRRQVDQLTNDKARVEVERDNLAEDIMRLREKLQEEM 192 Query: 165 -------NEIASFRRELDNSEAERAQHLKQIHDLQEH------LREKESQYL--ALEEQH 299 N + SFR+++DN+ R +++ LQE L E+E Q L ++EQH Sbjct: 193 LQREEAENTLQSFRQDVDNASLARLDLERKVESLQEEIAFLKKLHEEEIQELQAQIQEQH 252
>VIME_MACFA (Q4R4X4) Vimentin| Length = 465 Score = 34.3 bits (77), Expect = 0.33 Identities = 34/120 (28%), Positives = 52/120 (43%), Gaps = 26/120 (21%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQT----------- 164 E+LK Q R + E EM+ + R++D L D V +D L E Sbjct: 135 EQLKGQGKSRLGDLYEEEMR--ELRRQVDQLTNDKARVEVERDNLTEDIMRLREKLQEEM 192 Query: 165 -------NEIASFRRELDNSEAERAQHLKQIHDLQEH------LREKESQYL--ALEEQH 299 N + SFR+++DN+ R +++ LQE L E+E Q L ++EQH Sbjct: 193 LQREEAENTLQSFRQDVDNASLARLDLERKVESLQEEIAFLKKLHEEEIQELQAQIQEQH 252
>VIME_CERAE (P84198) Vimentin| Length = 465 Score = 34.3 bits (77), Expect = 0.33 Identities = 34/120 (28%), Positives = 52/120 (43%), Gaps = 26/120 (21%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQT----------- 164 E+LK Q R + E EM+ + R++D L D V +D L E Sbjct: 135 EQLKGQGKSRLGDLYEEEMR--ELRRQVDQLTNDKARVEVERDNLTEDIMRLREKLQEEM 192 Query: 165 -------NEIASFRRELDNSEAERAQHLKQIHDLQEH------LREKESQYL--ALEEQH 299 N + SFR+++DN+ R +++ LQE L E+E Q L ++EQH Sbjct: 193 LQREEAENTLQSFRQDVDNASLARLDLERKVESLQEEIAFLKKLHEEEIQELQAQIQEQH 252
>ACTN1_RAT (Q9Z1P2) Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform)| (Non-muscle alpha-actinin-1) (F-actin cross linking protein) Length = 892 Score = 34.3 bits (77), Expect = 0.33 Identities = 34/132 (25%), Positives = 61/132 (46%), Gaps = 13/132 (9%) Frame = +3 Query: 165 NEIASFRRELDNSEAERAQHLKQIHDL-----QEHLREKE------SQYLALEEQHRVAQ 311 NEI R LD+ AE+ + IH+ + LR+K+ S+ AL ++H + Sbjct: 384 NEIRRLER-LDHL-AEKFRQKASIHEAWTDGKEAMLRQKDYETATLSEIKALLKKHEAFE 441 Query: 312 DNILYKDEQLRDAHAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQ--QQYVEMQQ 485 ++ +++ A + E+D S S+ A ++ DQ+ A Q ++ +E + Sbjct: 442 SDLAAHQDRVEQIAAIAQELNELDYYDSPSVNARCQKICDQWDNLGALTQKRREALERTE 501 Query: 486 GFLHTIQRLQLE 521 L TI +L LE Sbjct: 502 KLLETIDQLYLE 513
>ACTN1_MOUSE (Q7TPR4) Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform)| (Non-muscle alpha-actinin-1) (F-actin cross linking protein) Length = 892 Score = 34.3 bits (77), Expect = 0.33 Identities = 34/132 (25%), Positives = 61/132 (46%), Gaps = 13/132 (9%) Frame = +3 Query: 165 NEIASFRRELDNSEAERAQHLKQIHDL-----QEHLREKE------SQYLALEEQHRVAQ 311 NEI R LD+ AE+ + IH+ + LR+K+ S+ AL ++H + Sbjct: 384 NEIRRLER-LDHL-AEKFRQKASIHEAWTDGKEAMLRQKDYETATLSEIKALLKKHEAFE 441 Query: 312 DNILYKDEQLRDAHAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQ--QQYVEMQQ 485 ++ +++ A + E+D S S+ A ++ DQ+ A Q ++ +E + Sbjct: 442 SDLAAHQDRVEQIAAIAQELNELDYYDSPSVNARCQKICDQWDNLGALTQKRREALERTE 501 Query: 486 GFLHTIQRLQLE 521 L TI +L LE Sbjct: 502 KLLETIDQLYLE 513
>ACTN1_HUMAN (P12814) Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform)| (Non-muscle alpha-actinin-1) (F-actin cross linking protein) Length = 892 Score = 34.3 bits (77), Expect = 0.33 Identities = 34/132 (25%), Positives = 61/132 (46%), Gaps = 13/132 (9%) Frame = +3 Query: 165 NEIASFRRELDNSEAERAQHLKQIHDL-----QEHLREKE------SQYLALEEQHRVAQ 311 NEI R LD+ AE+ + IH+ + LR+K+ S+ AL ++H + Sbjct: 384 NEIRRLER-LDHL-AEKFRQKASIHEAWTDGKEAMLRQKDYETATLSEIKALLKKHEAFE 441 Query: 312 DNILYKDEQLRDAHAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQ--QQYVEMQQ 485 ++ +++ A + E+D S S+ A ++ DQ+ A Q ++ +E + Sbjct: 442 SDLAAHQDRVEQIAAIAQELNELDYYDSPSVNARCQKICDQWDNLGALTQKRREALERTE 501 Query: 486 GFLHTIQRLQLE 521 L TI +L LE Sbjct: 502 KLLETIDQLYLE 513
>REST_HUMAN (P30622) Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170)| (Reed-Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1) Length = 1427 Score = 33.9 bits (76), Expect = 0.43 Identities = 30/124 (24%), Positives = 57/124 (45%), Gaps = 21/124 (16%) Frame = +3 Query: 15 AEKLKEQLHEREKYILELEMKLNDTHR-------ELDTLKIDH----QAVWANQDLLREQ 161 AE + + + K E L DT + ELDTLK ++ + + +++LL + Sbjct: 1077 AEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVE 1136 Query: 162 TNEIASFRRELDNSEAERAQHLKQIHDLQE----------HLREKESQYLALEEQHRVAQ 311 ++ FR+E++ + AQ +Q+ LQE R++ + + LEE+ V Sbjct: 1137 NQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEERSVLN 1196 Query: 312 DNIL 323 + +L Sbjct: 1197 NQLL 1200
>STMN3_HUMAN (Q9NZ72) Stathmin-3 (SCG10-like protein)| Length = 180 Score = 33.9 bits (76), Expect = 0.43 Identities = 29/104 (27%), Positives = 55/104 (52%), Gaps = 10/104 (9%) Frame = +3 Query: 153 REQTNEIASFRRELDNSEAER----AQHLKQIHDLQEHLREKESQYLALEEQH---RVAQ 311 +++ + ++ L+ +E R AQ LKQ+ + +EH E+E + ALEE + R A+ Sbjct: 76 KKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREH--EREVLHKALEENNNFSRQAE 133 Query: 312 DNILYKDE---QLRDAHAWITRVQEMDILQSQSLQAELRERTDQ 434 + + YK E ++R+AH R + + + + AE+R +Q Sbjct: 134 EKLNYKMELSKEIREAHLAALRER---LREKELHAAEVRRNKEQ 174
>ERC2_RAT (Q8K3M6) ERC protein 2 (CAZ-associated structural protein 1)| (CAST1) (Cast) (Cytomatrix protein p110) Length = 957 Score = 33.9 bits (76), Expect = 0.43 Identities = 35/171 (20%), Positives = 73/171 (42%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELD 197 + L+ +L E+E ++ + +L D E TL EI + L+ Sbjct: 493 DALRLRLEEKESFLNKKTKQLQDLTEEKGTL-----------------AGEIRDMKDMLE 535 Query: 198 NSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQE 377 E + K+I +LQE LR+K+ Q L+++ + Q + D L ++ + Sbjct: 536 VKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKER 595 Query: 378 MDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIE 530 + + + + RER ++ +F+++ ++++ + LQ EL E Sbjct: 596 IIERLKEQRERDDRERLEEI----ESFRKENKDLKE----KVNALQAELTE 638
>ERC2_MOUSE (Q6PH08) ERC protein 2 (CAZ-associated structural protein 1)| (CAST1) Length = 957 Score = 33.9 bits (76), Expect = 0.43 Identities = 35/171 (20%), Positives = 73/171 (42%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELD 197 + L+ +L E+E ++ + +L D E TL EI + L+ Sbjct: 493 DALRLRLEEKESFLNKKTKQLQDLTEEKGTL-----------------AGEIRDMKDMLE 535 Query: 198 NSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQE 377 E + K+I +LQE LR+K+ Q L+++ + Q + D L ++ + Sbjct: 536 VKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKER 595 Query: 378 MDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIE 530 + + + + RER ++ +F+++ ++++ + LQ EL E Sbjct: 596 IIERLKEQRERDDRERLEEI----ESFRKENKDLKE----KVNALQAELTE 638
>ERC2_HUMAN (O15083) ERC protein 2| Length = 957 Score = 33.9 bits (76), Expect = 0.43 Identities = 35/171 (20%), Positives = 73/171 (42%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELD 197 + L+ +L E+E ++ + +L D E TL EI + L+ Sbjct: 493 DALRLRLEEKESFLNKKTKQLQDLTEEKGTL-----------------AGEIRDMKDMLE 535 Query: 198 NSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQE 377 E + K+I +LQE LR+K+ Q L+++ + Q + D L ++ + Sbjct: 536 VKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKER 595 Query: 378 MDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIE 530 + + + + RER ++ +F+++ ++++ + LQ EL E Sbjct: 596 IIERLKEQRERDDRERLEEI----ESFRKENKDLKE----KVNALQAELTE 638
>INVO_CEBAL (P24709) Involucrin| Length = 428 Score = 33.9 bits (76), Expect = 0.43 Identities = 50/191 (26%), Positives = 82/191 (42%), Gaps = 21/191 (10%) Frame = +3 Query: 21 KLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNE---IASFRRE 191 +L EQ + KY+ + E +L + LK H Q L EQ ++ + ++ Sbjct: 174 ELPEQQSGQPKYLEQQEGQLKHLEEQKGQLK--HLEQQEGQLELPEQVDQPKHLEQLEKQ 231 Query: 192 LDN------------SEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDE 335 L++ E E+ +HL+Q + +HL ++E Q LE+ Q+ L E Sbjct: 232 LEHPEQQEGKLKKLEEEEEQLKHLEQQEEQLKHLEQQEGQLEHLEQ-----QEGELKHLE 286 Query: 336 QLRDAHAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQ----QYVEMQQGFLHTI 503 Q +++ L+ Q Q EL E+ Q GQ Q+ ++ E Q+G L + Sbjct: 287 QCEG---------QLEHLEQQEGQLELPEQ--QVGQSKHLEQEEKQLEHPEQQEGQLKHL 335 Query: 504 --QRLQLELIE 530 Q QLEL E Sbjct: 336 GKQEAQLELPE 346 Score = 30.0 bits (66), Expect = 6.2 Identities = 28/127 (22%), Positives = 62/127 (48%), Gaps = 4/127 (3%) Frame = +3 Query: 198 NSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQL--RDAHAWITRV 371 N E ++A + +Q +E REK+ LEE+ ++ + D++L RD + Sbjct: 94 NKEHQKAGNPEQQLKQEEAQREKQQLQGQLEEEKKLLDQQL---DQELAKRDDQLGTKKK 150 Query: 372 QEMDILQSQSLQAELRERTDQFGQC--WATFQQQYVEMQQGFLHTIQRLQLELIELRDRT 545 Q ++ + Q Q + E+ ++ + + Q +Y+E Q+G L ++ + +L L + Sbjct: 151 QLLEFPEQQEGQLKHLEQQEKPLELPEQQSGQPKYLEQQEGQLKHLEEQKGQLKHLEQQE 210 Query: 546 GEQDVSQ 566 G+ ++ + Sbjct: 211 GQLELPE 217
>POF21_ARATH (Q04088) Probable transcription factor PosF21 (AtbZIP59)| Length = 398 Score = 33.9 bits (76), Expect = 0.43 Identities = 51/192 (26%), Positives = 84/192 (43%), Gaps = 11/192 (5%) Frame = +3 Query: 12 AAEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRE 191 +A + KE+ + +YI ELE K+ E TL A LL+ TN + Sbjct: 214 SAARSKER---KTRYIFELERKVQTLQTEATTLS-------AQLTLLQRDTNGLT----- 258 Query: 192 LDNSEAE-RAQHLKQIHDLQEHLREKESQYLALEEQH------RVAQDNILYKDEQLRDA 350 ++N+E + R Q ++Q Q HL+++ ++ L E QH +VA + Y Sbjct: 259 VENNELKLRLQTMEQ----QVHLQDELNEALKEEIQHLKVLTGQVAPSALNYGSFGSNQQ 314 Query: 351 HAWITRVQEMDIL---QSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQL- 518 + IL Q Q LQ +++ Q Q QQQ + QQ + Q+ Q+ Sbjct: 315 QFYSNNQSMQTILAAKQFQQLQIHSQKQQQQQQQQQQQHQQQQQQQQQ---YQFQQQQMQ 371 Query: 519 ELIELRDRTGEQ 554 +L++ R + EQ Sbjct: 372 QLMQQRLQQQEQ 383
>GCC2_MOUSE (Q8CHG3) GRIP and coiled-coil domain-containing protein 2 (Golgi| coiled coil protein GCC185) Length = 1679 Score = 33.9 bits (76), Expect = 0.43 Identities = 40/175 (22%), Positives = 79/175 (45%), Gaps = 5/175 (2%) Frame = +3 Query: 15 AEKLKEQL-HEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRE 191 A+ +K++ HERE +LE K+N EL K + V RE N E Sbjct: 364 AQHIKDEFFHERE----DLEFKIN----ELLLAKEEQGYVVEKLKYEREDLNRQLCCAVE 415 Query: 192 LDNSEAERAQHLKQIHDLQEHLREKESQ----YLALEEQHRVAQDNILYKDEQLRDAHAW 359 QH K+I LQEH +++ S+ +++ E+ ++A ++++ + L++ Sbjct: 416 ---------QHNKEIQRLQEHHQKEVSELSETFISGSEKEKLA---LMFEIQGLKEQCEN 463 Query: 360 ITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLEL 524 + ++ +L +SL+ + + G+ Q++ M+Q + LQ +L Sbjct: 464 LQHEKQEVVLNYESLREMMEILQTELGESAGKISQEFETMKQQQASDVHELQQKL 518 Score = 32.3 bits (72), Expect = 1.3 Identities = 46/222 (20%), Positives = 93/222 (41%), Gaps = 26/222 (11%) Frame = +3 Query: 18 EKLKE------QLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIAS 179 +K+KE +L E + + + +L T +EL+ +K D A Q L EIA Sbjct: 1103 QKIKEHVSTVNELEELQLQFQKEKKQLQKTMQELELVKKD-----AQQTTLMNM--EIAD 1155 Query: 180 FRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAW 359 + R + + I DL++ ++ ++ + L+E+ Q ++ + +E+ Sbjct: 1156 YERLMKELNQKLTNKNSTIEDLEQEMKIQKEKQETLQEEITSLQSSVQHYEEKNTKIKQL 1215 Query: 360 I--TRVQEMDILQSQS----LQAELRERTDQFGQCWATFQQQYVEM--QQGFLH------ 497 + T+ + D Q+++ LQA L+ + Q ++ Q EM ++ +H Sbjct: 1216 LVKTKKELADAKQAETDHLLLQASLKGELEASQQQVEVYKIQLAEMTSEKHKIHEHLKTS 1275 Query: 498 ------TIQRLQLELIELRDRTGEQDVSQAAQDGSAESSYVQ 605 T+ Q ++ L++ + QAA ES V+ Sbjct: 1276 AEQHQRTLSAYQQRVVALQEESRAAKAEQAAVTSEFESYKVR 1317
>KRP85_STRPU (P46872) Kinesin-II 85 kDa subunit (KRP-85/95 85 kDa subunit)| Length = 699 Score = 33.9 bits (76), Expect = 0.43 Identities = 46/231 (19%), Positives = 99/231 (42%), Gaps = 38/231 (16%) Frame = +3 Query: 24 LKEQLHEREKYILE----LEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIA----- 176 +++++ E +K + E +E N HREL + + +Q +L E+ N I Sbjct: 420 MQKKIDEEKKALEEKKDMVEEDRNTVHRELQRRESELHKAQDDQKILNEKLNAIQKKLIV 479 Query: 177 --------SFRRE--LDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILY 326 S +E L+ S E + + + +++ + E+E + + +EE++ QD Sbjct: 480 GGVDLLAKSEEQEQLLEQSALEMKERMAKQESMRKMMEEREQERMDIEEKYSSLQDEAHG 539 Query: 327 KDEQLR-------DAHAWITRVQEMDILQSQSLQAELRERTDQFGQCW----ATFQQQYV 473 K ++L+ A + + +Q + ++L +RE + + + Q++ Sbjct: 540 KTKKLKKVWTMLMQAKSEVADMQAEHQREMEALLENVRELSRELRLSMLIIDSFIPQEFQ 599 Query: 474 EMQQGFLH---TIQRLQLELI-----ELRDRTGEQDVSQAAQDGSAESSYV 602 EM + ++H I QL+ + +R +T D ++ G A+ S V Sbjct: 600 EMIEQYVHWNEDIGEWQLKCVAYTGNNMRKQTPVADKDKSLAYGEADLSNV 650
>CI093_HUMAN (Q6TFL3) Protein C9orf93| Length = 1326 Score = 33.9 bits (76), Expect = 0.43 Identities = 39/160 (24%), Positives = 72/160 (45%), Gaps = 34/160 (21%) Frame = +3 Query: 21 KLKEQLHEREKYILELEMKLNDT-----HRELDTLKIDHQAVWANQDLLREQTNEIA--- 176 +L+E+ E E+ L+ ++ DT H++++ L+ +H DLLR QT+E+ Sbjct: 207 RLQEEQWEAERRELQFIVQEQDTAVQNMHKKVEKLETEHMDC---SDLLRRQTSELEFST 263 Query: 177 ----SFRRELD-----------NSEAERAQHLK----------QIHDLQEHLR-EKESQY 278 R+E + N EAERA HL+ +I DL+ L+ EK SQ Sbjct: 264 QREERLRKEFEATTLRVRKLEENIEAERAAHLESKFNSEIIQLRIRDLEGALQVEKASQA 323 Query: 279 LALEEQHRVAQDNILYKDEQLRDAHAWITRVQEMDILQSQ 398 A+ + + + + R+ H ++++L+ + Sbjct: 324 EAVADLEIIKNEFKEVESAYEREKHNAQESFAKLNLLEKE 363 Score = 29.6 bits (65), Expect = 8.1 Identities = 33/123 (26%), Positives = 57/123 (46%), Gaps = 2/123 (1%) Frame = +3 Query: 141 QDLLREQTNEIASFRRELDNSEAERAQHLKQIHDLQEHLRE--KESQYLALEEQHRVAQD 314 Q+ L + +NE + ELD+++ + H K I +LQ+ L + KE +L + R A Sbjct: 466 QNKLEDASNEEKACN-ELDSTKQKIDSHTKNIKELQDKLADVNKELSHLHTKCADREALI 524 Query: 315 NILYKDEQLRDAHAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFL 494 + L K E H W E + Q+ ++EL++ + F + E + FL Sbjct: 525 STL-KVELQNVLHCW-----EKEKAQAAQSESELQKLSQAF--------HKDAEEKLTFL 570 Query: 495 HTI 503 HT+ Sbjct: 571 HTL 573
>TAXB1_HUMAN (Q86VP1) Tax1-binding protein 1 (TRAF6-binding protein)| Length = 789 Score = 33.9 bits (76), Expect = 0.43 Identities = 37/139 (26%), Positives = 64/139 (46%), Gaps = 2/139 (1%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELD 197 +KLK+ HERE+ LE ++K +EL + + + + N L+ +E+ + + Sbjct: 257 DKLKKAQHEREQ--LECQLKTEKDEKELYKVHLKNTEI-ENTKLM----SEVQTLKNLDG 309 Query: 198 NSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWI--TRV 371 N E+ ++I LQ L EKE+ +D K EQLR A + TR Sbjct: 310 NKESVITHFKEEIGRLQLCLAEKENLQRTFLLTTSSKEDTCFLK-EQLRKAEEQVQATRQ 368 Query: 372 QEMDILQSQSLQAELRERT 428 + + + + S +R+RT Sbjct: 369 EVVFLAKELSDAVNVRDRT 387
>DESM_XENLA (P23239) Desmin| Length = 458 Score = 33.9 bits (76), Expect = 0.43 Identities = 36/166 (21%), Positives = 71/166 (42%), Gaps = 13/166 (7%) Frame = +3 Query: 120 HQAVWANQDLLREQTNEIASFRR-------ELDNSEAERAQHLKQIHDLQEHLREKESQY 278 +QA N D +R+ E+ +R E+D + ++Q+ DL+E + + Y Sbjct: 292 NQAAKKNNDAMRQSKQEMMEYRHQIQSYTCEIDALKGTNDSLMRQMRDLEEKFSGEAAGY 351 Query: 279 L----ALEEQHRVAQDNILYKDEQLRDAHAWITRVQEMDILQSQSLQAELRERTDQFGQC 446 LEE+ R +D + + +D + +M+I + L R Q Sbjct: 352 QDTIGRLEEEIRNMKDEMARHLREYQDL-LNVKMALDMEIATYRKLLEGEESRITLPIQT 410 Query: 447 WA--TFQQQYVEMQQGFLHTIQRLQLELIELRDRTGEQDVSQAAQD 578 ++ +F++ E + +HT + + ++ IE RD + SQ Q+ Sbjct: 411 FSALSFRETSPEQRASEVHTKKTVMIKTIETRDGEVLSEASQQHQE 456
>SFPQ_HUMAN (P23246) Splicing factor, proline- and glutamine-rich| (Polypyrimidine tract-binding protein-associated splicing factor) (PTB-associated splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100-kDa DNA-pairing protein) (hPOMp Length = 707 Score = 33.5 bits (75), Expect = 0.56 Identities = 32/116 (27%), Positives = 55/116 (47%), Gaps = 6/116 (5%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELD 197 E K+Q + EK + + + KL E++ +HQA QDL+R Q E EL Sbjct: 499 EMEKQQREQVEKNMKDAKDKLES---EMEDAYHEHQANLLRQDLMRRQ--EELRRMEELH 553 Query: 198 NSEAERAQHLKQIHDLQEHLREKES--QYLALEEQHRVAQD----NILYKDEQLRD 347 N E ++ + ++ + + RE+E + +EEQ R ++ + Y D + RD Sbjct: 554 NQEMQKRKEMQLRQEEERRRREEEMMIRQREMEEQMRRQREESYSRMGYMDPRERD 609
>Y1732_AQUAE (O67622) UPF0144 protein aq_1732| Length = 558 Score = 33.5 bits (75), Expect = 0.56 Identities = 34/186 (18%), Positives = 88/186 (47%), Gaps = 2/186 (1%) Frame = +3 Query: 6 VVAAEKLKEQLHEREKYILELEMKLNDTHREL--DTLKIDHQAVWANQDLLREQTNEIAS 179 V + + L+E + E+ I E + K +E KI +A + L+RE E+ Sbjct: 37 VPSPQILEEAKSKAEEIIKEAKEKAEVILKEAKESAEKIVREAEEKAEKLIREAKEEVER 96 Query: 180 FRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAW 359 + E++ + E + + + + HL + ++ ALE++ ++ +L+++ +L+D Sbjct: 97 IKEEVERRKKELKEREENVLAKERHL---DRRWEALEKR----EEELLHRERELKDFERS 149 Query: 360 ITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRD 539 + R ++ +I + ++E ++ +++ E+Q+ T++ + E+I+ + Sbjct: 150 LERWRD-EIRHKEEELKHMKEEVEELK------KKELEELQRIAKLTLEEARQEIIKKVE 202 Query: 540 RTGEQD 557 ++D Sbjct: 203 EEAKKD 208
>MRCKB_MOUSE (Q7TT50) Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1)| (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta) Length = 1713 Score = 33.5 bits (75), Expect = 0.56 Identities = 31/142 (21%), Positives = 60/142 (42%), Gaps = 29/142 (20%) Frame = +3 Query: 18 EKLKEQLHEREKYILELEMKLNDT---------------------HRELDTLKIDHQAVW 134 + +++ L + EK ELE +L D REL+ LK+ Sbjct: 613 DSMRQDLRKSEKSRKELEARLEDAAAEASKERKLREHSESFCKQMERELEALKVKQGG-- 670 Query: 135 ANQDLLREQTNEIASFRRELDNS----EAE----RAQHLKQIHDLQEHLREKESQYLALE 290 E EI+ R EL+ E E A H+ ++ ++++ + + ES LAL+ Sbjct: 671 RGPGAASEHQQEISKIRSELEKKVLFYEEELVRREASHVLEVKNVKKEVHDSESHQLALQ 730 Query: 291 EQHRVAQDNILYKDEQLRDAHA 356 ++ + +D + ++ R+ H+ Sbjct: 731 KEVLMLKDKL---EKSKRERHS 749
>NUP62_RAT (P17955) Nuclear pore glycoprotein p62 (62 kDa nucleoporin)| Length = 525 Score = 33.5 bits (75), Expect = 0.56 Identities = 24/98 (24%), Positives = 46/98 (46%), Gaps = 4/98 (4%) Frame = +3 Query: 33 QLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDNSEAE 212 Q++ ++ ++E K+ HRE++ +K+D + + D + Q E+ L+ S E Sbjct: 360 QVNAWDRTLIENGEKITSLHREVEKVKLDQKRLDQELDFILSQQKELEDLLSPLEESVKE 419 Query: 213 RAQHLKQIHDLQEHLREKESQYLALE----EQHRVAQD 314 ++ + LQ E+E Y E + R+AQD Sbjct: 420 QSGTIY----LQHADEEREKTYKLAENIDAQLKRMAQD 453
>CCDC6_HUMAN (Q16204) Coiled-coil domain-containing protein 6 (H4 protein)| (Papillary thyroid carcinoma-encoded protein) Length = 585 Score = 33.5 bits (75), Expect = 0.56 Identities = 34/153 (22%), Positives = 79/153 (51%), Gaps = 12/153 (7%) Frame = +3 Query: 12 AAEKLKEQLHEREKYILE-LEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRR 188 A+ ++ + + E++I L K+ +E +TL ++++ ++ L TNE++ Sbjct: 97 ASVTIQARAEQEEEFISNTLFKKIQALQKEKETLAVNYEK---EEEFL---TNELSRKLM 150 Query: 189 ELDNSEAERAQHLK-----QIHDLQEHLREKE----SQYLALEE--QHRVAQDNILYKDE 335 +L + + E QHL+ Q++ L + +++ E S+ L LE+ + ++ +N L +++ Sbjct: 151 QLQHEKGELEQHLEQEQEFQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQ 210 Query: 336 QLRDAHAWITRVQEMDILQSQSLQAELRERTDQ 434 + W + MD L++++ L+E+ DQ Sbjct: 211 EALVNRLW----KRMDKLEAET--RILQEKLDQ 237
>CK5P2_MOUSE (Q8K389) CDK5 regulatory subunit-associated protein 2 (CDK5| activator-binding protein C48) Length = 1822 Score = 33.5 bits (75), Expect = 0.56 Identities = 45/183 (24%), Positives = 73/183 (39%), Gaps = 4/183 (2%) Frame = +3 Query: 84 DTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRELDNS----EAERAQHLKQIHDLQE 251 D + DT K A QDLL E EI + R+ L+ S E R Q +Q + + Sbjct: 1380 DPKPDSDTEKYPAMASHFPQDLLMEHIQEIRTLRKHLEESIKTNEKLRKQLERQGSETDQ 1439 Query: 252 HLREKESQYLALEEQHRVAQDNILYKDEQLRDAHAWITRVQEMDILQSQSLQAELRERTD 431 R + LAL H I + LR + ++ + E Q +LRE Sbjct: 1440 GSRNVSACGLAL---HSSLTSEIHF----LRKQNEALSMMLEKGSKDKQKESEKLRESLA 1492 Query: 432 QFGQCWATFQQQYVEMQQGFLHTIQRLQLELIELRDRTGEQDVSQAAQDGSAESSYVQSK 611 + + Q +Y +++ +RLQ ++IE Q++++ E S VQ + Sbjct: 1493 RKAESLEQLQLEYTSVRE----ENERLQRDIIE--KERHNQELTEEVCSSRQELSRVQEE 1546 Query: 612 GSS 620 S Sbjct: 1547 AKS 1549 Score = 30.0 bits (66), Expect = 6.2 Identities = 25/102 (24%), Positives = 49/102 (48%), Gaps = 20/102 (19%) Frame = +3 Query: 60 LELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIAS-------------------- 179 LE+ + L + R ++ LK+ ++ A L+E+ +++AS Sbjct: 209 LEMTLALEEKDRLIEELKLSLKSKEALIQCLKEEKSQMASPDENVSSGELRGLSATLREE 268 Query: 180 FRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRV 305 R+ + + ER ++I LQE LREKE + +A E+++ + Sbjct: 269 KERDAEEWQKERNHFEERIQALQEDLREKERE-IATEKKNNL 309
>GOGA4_MOUSE (Q91VW5) Golgin subfamily A member 4 (tGolgin-1)| Length = 2238 Score = 33.5 bits (75), Expect = 0.56 Identities = 39/196 (19%), Positives = 80/196 (40%), Gaps = 21/196 (10%) Frame = +3 Query: 15 AEKLKEQLHEREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRREL 194 AE + + E+ L+L+ +L + ++D L + + D +N+ + ++++ Sbjct: 1408 AEAISALSKQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVD---HWSNKFSEWKKK- 1463 Query: 195 DNSEAERAQHLKQIHDLQEHL-------REKESQYLALEE--------------QHRVAQ 311 +++ AQH I DLQ L REKE Q L+E + V + Sbjct: 1464 --AQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRK 1521 Query: 312 DNILYKDEQLRDAHAWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGF 491 + K+ L A + Q +++ + + ++ + + + QQ G Sbjct: 1522 SKMEKKECDLETA----LKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDTEHSGL 1577 Query: 492 LHTIQRLQLELIELRD 539 + +Q L+ EL E +D Sbjct: 1578 VQRLQHLE-ELGEEKD 1592 Score = 32.3 bits (72), Expect = 1.3 Identities = 43/213 (20%), Positives = 89/213 (41%), Gaps = 13/213 (6%) Frame = +3 Query: 12 AAEKLKEQLH------EREKYILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEI 173 A ++L E+L ++ K LE E++ H + + I Q + + +E+ Sbjct: 719 ARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQELTVRRAEKALKDEL 778 Query: 174 ASFRRELDNSEAERAQHLKQIHDLQEHLREKESQYLALEEQHRVAQDNILYKDEQLRDAH 353 + LD + + ++ DL+ HL++ A E Q +A+ ++L+ ++ Sbjct: 779 SRLGALLDERDEHLRERQARVQDLEAHLQKS-----AGELQQALAKLDLLHSEQSAAREQ 833 Query: 354 AWITRVQEMDILQSQSLQAELRERTDQFGQCWATFQQQYVEMQQGFLHT-----IQRLQL 518 A +++ +Q + L E + + +Q VEM+ H QR Q+ Sbjct: 834 AGAYE-EQLAQMQQKVLDLETEK---------SLLTKQVVEMETHKKHVCEELDAQRAQV 883 Query: 519 ELIELRDRTGEQDVSQAA--QDGSAESSYVQSK 611 + +E + E+ V A QD ++S V+ + Sbjct: 884 QQLERQRSELEEKVRSLAQLQDSQLKNSTVEKE 916 Score = 30.0 bits (66), Expect = 6.2 Identities = 35/114 (30%), Positives = 55/114 (48%), Gaps = 4/114 (3%) Frame = +3 Query: 21 KLKEQLHEREKY---ILELEMKLNDTHRELDTLKIDHQAVWANQDLLREQTNEIASFRRE 191 KL+E E E Y ILELE L + +E T + +H AV L + N+ +E Sbjct: 574 KLQELGQEAEAYRTRILELETSLEKSLQESKT-QSEHLAVH-----LEAEKNK---HNKE 624 Query: 192 LDNSEAERAQHLKQIHDLQEHLREKESQYL-ALEEQHRVAQDNILYKDEQLRDA 350 L A QH ++ LQ+ ++ L +L +QH+ A + + K +Q +DA Sbjct: 625 LT---ALAEQHRTEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDA 675 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 79,986,187 Number of Sequences: 219361 Number of extensions: 1454961 Number of successful extensions: 6835 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 5879 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6661 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 6143359464 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
