ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bags39k17 |
|---|---|
| Clone Library Name | barley_pub |
>PET8_YEAST (P38921) Putative mitochondrial carrier protein PET8| Length = 284 Score = 94.0 bits (232), Expect = 3e-19 Identities = 57/176 (32%), Positives = 92/176 (52%), Gaps = 4/176 (2%) Frame = +2 Query: 113 VPKELITQRLQSGAATGRSWQVLLQILQTDGFFGL----YAGYAATLLRNLPAGVLSYSS 280 VP E++ QR Q + T SWQ L IL+ D GL Y G++ T++R +P + + Sbjct: 113 VPAEVVKQRTQVHS-TNSSWQTLQSILRNDNKEGLRKNLYRGWSTTIMREIPFTCIQFPL 171 Query: 281 FEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVV 460 +EYLK + + P + +CG++AG I+A TTPLD +KTRLM + + ++ Sbjct: 172 YEYLKKTWAKANGQSQVEPWKGAICGSIAGGIAAATTTPLDFLKTRLMLN---KTTASLG 228 Query: 461 GTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMILKSYLESCERKA 628 + + EEG G+GPR + + AI +ET ++ KS+ + E +A Sbjct: 229 SVIIRIYREEGPAVFFSGVGPRTMWISAGGAIFLGMYETVHSLLSKSFPTAGEMRA 284 Score = 36.6 bits (83), Expect = 0.065 Identities = 28/97 (28%), Positives = 46/97 (47%), Gaps = 4/97 (4%) Frame = +2 Query: 344 SVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGP 523 S+L GA AG + + P+D +KTRL + G A G G+ RG+G Sbjct: 7 SLLSGAAAGTSTDLVFFPIDTIKTRLQAKGG-------------FFANGGYKGIYRGLGS 53 Query: 524 RVLHSACFAAIGYCAFE----TARLMILKSYLESCER 622 V+ SA A++ + +++ +R I K Y + E+ Sbjct: 54 AVVASAPGASLFFISYDYMKVKSRPYISKLYSQGSEQ 90 Score = 35.0 bits (79), Expect = 0.19 Identities = 42/170 (24%), Positives = 70/170 (41%), Gaps = 25/170 (14%) Frame = +2 Query: 140 LQSGAATGRSWQVLLQILQT--------DGFF------GLYAGYAATLLRNLPAGVLSYS 277 L SGAA G S ++ + T GFF G+Y G + ++ + P L + Sbjct: 8 LLSGAAAGTSTDLVFFPIDTIKTRLQAKGGFFANGGYKGIYRGLGSAVVASAPGASLFFI 67 Query: 278 SFEYLKAFA------LSKSNAPNLTPGESVLCGALAGAISAGLT-TPLDVVKTRLMTRVG 436 S++Y+K + L + L + + + G I A L P +VVK R T+V Sbjct: 68 SYDYMKVKSRPYISKLYSQGSEQLIDTTTHMLSSSIGEICACLVRVPAEVVKQR--TQVH 125 Query: 437 AQGSRTVVGTMQEVIAEEGLMGLS----RGIGPRVLHSACFAAIGYCAFE 574 + S T+Q ++ + GL RG ++ F I + +E Sbjct: 126 STNSSW--QTLQSILRNDNKEGLRKNLYRGWSTTIMREIPFTCIQFPLYE 173
>YDE9_SCHPO (Q10442) Putative mitochondrial carrier C12B10.09| Length = 345 Score = 92.0 bits (227), Expect = 1e-18 Identities = 56/142 (39%), Positives = 86/142 (60%), Gaps = 2/142 (1%) Frame = +2 Query: 113 VPKELITQRLQSGAATGRSWQVLLQILQTDGFF-GLYAGYAATLLRNLPAGVLSYSSFEY 289 VP E+I QR Q+ T S +L IL+++ + YAGY T+ R +P ++ + +E+ Sbjct: 183 VPTEVIKQRAQASGGTLSSRNILQTILKSNNVWRDFYAGYGITIAREIPFTLIQFPIWEH 242 Query: 290 LKA-FALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGT 466 LK + + S NL E+ + G++AG I+A LTTP DVVKTR+MT +Q + V T Sbjct: 243 LKLKWRIKHSRNKNLAH-EAAISGSIAGGIAAALTTPFDVVKTRIMT---SQQRLSYVFT 298 Query: 467 MQEVIAEEGLMGLSRGIGPRVL 532 ++ ++A EG + L +GI PRVL Sbjct: 299 IKSIVAHEGFLALYKGIVPRVL 320 Score = 30.8 bits (68), Expect = 3.6 Identities = 24/88 (27%), Positives = 39/88 (44%), Gaps = 5/88 (5%) Frame = +2 Query: 359 ALAGAISAGLTT-----PLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGP 523 AL I AGL P+D +KTRL + G + G G+ RG+G Sbjct: 85 ALGAGICAGLAVDLSLFPIDTLKTRLQAKGG-------------FVKNGGFHGVYRGLGS 131 Query: 524 RVLHSACFAAIGYCAFETARLMILKSYL 607 ++ SA A++ + +E + + +S L Sbjct: 132 ILVGSAPGASLFFTTYENMKSRLSQSGL 159
>MRS4_YEAST (P23500) Mitochondrial RNA-splicing protein MRS4| Length = 304 Score = 81.6 bits (200), Expect = 2e-15 Identities = 63/200 (31%), Positives = 89/200 (44%), Gaps = 11/200 (5%) Frame = +2 Query: 35 LRSHLPPFLVPPLXXXXXXXXXXXXMVPKELITQRLQSGAATGRSWQVLLQILQTDGFFG 214 +++H P + L M P + + QRLQ R W V QI Q +GF Sbjct: 115 MQTHQP--MKTALSGTIATIAADALMNPFDTVKQRLQLDTNL-RVWNVTKQIYQNEGFAA 171 Query: 215 LYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTT 394 Y Y TL N+P ++ +E F + N+ N P LCG ++GA A LTT Sbjct: 172 FYYSYPTTLAMNIPFAAFNFMIYESASKF-FNPQNSYN--PLIHCLCGGISGATCAALTT 228 Query: 395 PLDVVKTRLMTRVGAQGSRTV----------VGTMQEVIAE-EGLMGLSRGIGPRVLHSA 541 PLD +KT L R GS TV G I E G G RG+ PR++ + Sbjct: 229 PLDCIKTVLQVR----GSETVSIEIMKDANTFGRASRAILEVHGWKGFWRGLKPRIVANI 284 Query: 542 CFAAIGYCAFETARLMILKS 601 AI + A+E A+ ++K+ Sbjct: 285 PATAISWTAYECAKHFLMKN 304 Score = 35.4 bits (80), Expect = 0.15 Identities = 21/79 (26%), Positives = 37/79 (46%), Gaps = 6/79 (7%) Frame = +2 Query: 347 VLCGALAGAISAGLTTPLDVVKTRLMTR-VGAQGSRTVVGTMQEVIAEEGLMGLSRGIGP 523 +L GA AG + L P+D +KTR+ + S ++ + ++ EG M L +G+ Sbjct: 27 LLAGAFAGIMEHSLMFPIDALKTRVQAAGLNKAASTGMISQISKISTMEGSMALWKGVQS 86 Query: 524 RVL-----HSACFAAIGYC 565 +L H+ F +C Sbjct: 87 VILGAGPAHAVYFGTYEFC 105
>CMC2_HUMAN (Q9UJS0) Calcium-binding mitochondrial carrier protein Aralar2| (Mitochondrial aspartate glutamate carrier 2) (Solute carrier family 25 member 13) (Citrin) Length = 675 Score = 79.7 bits (195), Expect = 7e-15 Identities = 49/145 (33%), Positives = 78/145 (53%), Gaps = 3/145 (2%) Frame = +2 Query: 116 PKELITQRLQ-SGAATGRSWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYL 292 P E++ RLQ +G T L +++ GFFG+Y G A LR++P + + + ++ Sbjct: 448 PLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHV 507 Query: 293 KAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLM--TRVGAQGSRTVVGT 466 KA ++ ++PG +L GA+AG +A L TP DV+KTRL R G V+ Sbjct: 508 KASFANEDG--QVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDC 565 Query: 467 MQEVIAEEGLMGLSRGIGPRVLHSA 541 ++++ EEG L +G G RV S+ Sbjct: 566 FRKILREEGPKALWKGAGARVFRSS 590 Score = 51.2 bits (121), Expect = 3e-06 Identities = 40/156 (25%), Positives = 70/156 (44%), Gaps = 9/156 (5%) Frame = +2 Query: 116 PKELITQRLQSGAATG---------RSWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVL 268 P +L+ R+Q+ +TG S+ ++L+ +GFFGLY G LL P + Sbjct: 348 PIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAI 407 Query: 269 SYSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGS 448 + ++++ + K + L +L G AG T PL++VK RL +V + + Sbjct: 408 KLTVNDFVRDKFMHKDGSVPL--AAEILAGGCAGGSQVIFTNPLEIVKIRL--QVAGEIT 463 Query: 449 RTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAI 556 + V+ + G G+ +G L F+AI Sbjct: 464 TGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAI 499 Score = 39.7 bits (91), Expect = 0.008 Identities = 25/73 (34%), Positives = 39/73 (53%), Gaps = 6/73 (8%) Frame = +2 Query: 356 GALAGAISAGLTTPLDVVKTRLMTR------VGAQGSRTVVGTMQEVIAEEGLMGLSRGI 517 G++AGA+ A P+D+VKTR+ + VG + ++V+ EG GL RG+ Sbjct: 335 GSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGL 394 Query: 518 GPRVLHSACFAAI 556 P++L A AI Sbjct: 395 LPQLLGVAPEKAI 407
>DIF1_CAEEL (Q27257) Protein dif-1| Length = 312 Score = 78.2 bits (191), Expect = 2e-14 Identities = 53/159 (33%), Positives = 79/159 (49%), Gaps = 13/159 (8%) Frame = +2 Query: 110 MVPKELITQRLQ--------SGAATGRSWQVLLQILQTDGFFGLYAGYAATLLRNLPAGV 265 MVP E I LQ SG V+ ++ + G +Y G ATLLR++PA Sbjct: 122 MVPGERIKCLLQVQQAGSAGSGVHYDGPLDVVKKLYKQGGISSIYRGTGATLLRDIPASA 181 Query: 266 LSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQG 445 S +EYLK + L+PG +++ G LAG + G+ P DV+K+RL T + Sbjct: 182 AYLSVYEYLKKKFSGEGAQRTLSPGATLMAGGLAGIANWGVCIPADVLKSRLQTAPEGKY 241 Query: 446 SRTVVGTMQEVIAEEGLMGLSRGIGPRVL-----HSACF 547 + G ++EV+ EEG L +G P +L ++ACF Sbjct: 242 PDGIRGVLREVLREEGPRALFKGFWPVMLRAFPANAACF 280 Score = 32.0 bits (71), Expect = 1.6 Identities = 30/130 (23%), Positives = 57/130 (43%), Gaps = 5/130 (3%) Frame = +2 Query: 200 DGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAIS 379 +GFF LY G AA L+ P + + K + + +T ++ GALAG + Sbjct: 60 EGFFALYKGMAAPLVGVSPLFAVFFGGCAVGK-WLQQTDPSQEMTFIQNANAGALAGVFT 118 Query: 380 AGLTTPLDVVKTRL-MTRVGAQGSRT----VVGTMQEVIAEEGLMGLSRGIGPRVLHSAC 544 + P + +K L + + G+ GS + ++++ + G+ + RG G +L Sbjct: 119 TIVMVPGERIKCLLQVQQAGSAGSGVHYDGPLDVVKKLYKQGGISSIYRGTGATLLRDIP 178 Query: 545 FAAIGYCAFE 574 +A +E Sbjct: 179 ASAAYLSVYE 188
>PET8_ASHGO (O60029) Putative mitochondrial carrier protein PET8| Length = 271 Score = 78.2 bits (191), Expect = 2e-14 Identities = 54/158 (34%), Positives = 83/158 (52%), Gaps = 4/158 (2%) Frame = +2 Query: 113 VPKELITQRLQSGAATGRSWQVLLQILQT---DGFF-GLYAGYAATLLRNLPAGVLSYSS 280 VP E+I QR Q+ T S Q L IL+ +G GLY G+ T++R +P + + Sbjct: 112 VPAEVIKQRTQTHH-TNSSLQTLRLILRDPTGEGVVRGLYRGWWTTIMREIPFTCIQFPL 170 Query: 281 FEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVV 460 +EYLK + + ++ + +CG+LAG I+A TTPLDV+KTR+M + ++ Sbjct: 171 YEYLKKKWAAYAEIERVSAWQGAVCGSLAGGIAAAATTPLDVLKTRMMLH---ERRVPML 227 Query: 461 GTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFE 574 + + EEG RGIGPR + + AI +E Sbjct: 228 HLARTLFREEGARVFFRGIGPRTMWISAGGAIFLGVYE 265 Score = 32.0 bits (71), Expect = 1.6 Identities = 21/80 (26%), Positives = 38/80 (47%) Frame = +2 Query: 344 SVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGP 523 S++ GA AG + + P+D +KTRL + G G G+ RG+G Sbjct: 8 SLVSGAAAGTSTDVVFFPIDTLKTRLQAKGG-------------FFHNGGYRGIYRGLGS 54 Query: 524 RVLHSACFAAIGYCAFETAR 583 V+ SA A++ + +++ + Sbjct: 55 AVVASAPGASLFFVTYDSMK 74
>CMC2_MOUSE (Q9QXX4) Calcium-binding mitochondrial carrier protein Aralar2| (Mitochondrial aspartate glutamate carrier 2) (Solute carrier family 25 member 13) (Citrin) Length = 676 Score = 78.2 bits (191), Expect = 2e-14 Identities = 48/145 (33%), Positives = 77/145 (53%), Gaps = 3/145 (2%) Frame = +2 Query: 116 PKELITQRLQ-SGAATGRSWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYL 292 P E++ RLQ +G T L +++ GFFG+Y G A LR++P + + + ++ Sbjct: 449 PLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHV 508 Query: 293 KAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLM--TRVGAQGSRTVVGT 466 KA ++ ++PG +L GA+AG +A L TP DV+KTRL R G V Sbjct: 509 KASFANEDG--QVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYNGVTDC 566 Query: 467 MQEVIAEEGLMGLSRGIGPRVLHSA 541 ++++ EEG L +G+ RV S+ Sbjct: 567 FRKILREEGPKALWKGVAARVFRSS 591 Score = 49.3 bits (116), Expect = 1e-05 Identities = 39/156 (25%), Positives = 69/156 (44%), Gaps = 9/156 (5%) Frame = +2 Query: 116 PKELITQRLQSGAATG---------RSWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVL 268 P +L+ R+Q+ +TG S+ ++L+ +GFFGLY G LL P + Sbjct: 349 PIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAI 408 Query: 269 SYSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGS 448 + ++++ + K + L + G AG T PL++VK RL +V + + Sbjct: 409 KLTVNDFVRDKFMHKDGSVPLL--AEIFAGGCAGGSQVIFTNPLEIVKIRL--QVAGEIT 464 Query: 449 RTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAI 556 + V+ + G G+ +G L F+AI Sbjct: 465 TGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAI 500 Score = 40.0 bits (92), Expect = 0.006 Identities = 25/73 (34%), Positives = 39/73 (53%), Gaps = 6/73 (8%) Frame = +2 Query: 356 GALAGAISAGLTTPLDVVKTRLMTR------VGAQGSRTVVGTMQEVIAEEGLMGLSRGI 517 G++AGA+ A P+D+VKTR+ + VG + ++V+ EG GL RG+ Sbjct: 336 GSIAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGL 395 Query: 518 GPRVLHSACFAAI 556 P++L A AI Sbjct: 396 LPQLLGVAPEKAI 408
>CMC1_CAEEL (Q21153) Probable calcium-binding mitochondrial carrier K02F3.2| Length = 707 Score = 72.0 bits (175), Expect = 1e-12 Identities = 53/181 (29%), Positives = 87/181 (48%), Gaps = 4/181 (2%) Frame = +2 Query: 116 PKELITQRLQSGAATGRSWQVL--LQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEY 289 P E++ RLQ+ ++ + + +L+ GF GLY G A LR++P + + ++ + Sbjct: 488 PLEIVKIRLQTAGEVQQAGKKIGVFTVLKELGFLGLYKGSRACFLRDIPFSAIYFPAYAH 547 Query: 290 LKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLM--TRVGAQGSRTVVG 463 K A + + N +PG +AG +AGL TP DV+KTRL R G V+ Sbjct: 548 AK-LASADEDGMN-SPGTLFASAFIAGVPAAGLVTPADVIKTRLQVAARAGQTTYNGVID 605 Query: 464 TMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMILKSYLESCERKAADEMK 643 +++I EEG M L +G RV S+ A+ +E + + + S R E+ Sbjct: 606 CARKLIKEEGPMSLWKGTAARVCRSSPQFAVTLLTYEVLQRLFYVDFAGS--RPTGSELA 663 Query: 644 T 646 T Sbjct: 664 T 664 Score = 50.4 bits (119), Expect = 4e-06 Identities = 41/166 (24%), Positives = 71/166 (42%), Gaps = 9/166 (5%) Frame = +2 Query: 116 PKELITQRLQSGAATG---------RSWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVL 268 P +L+ R+Q+ +G S ++++ +G GLY G ++ P + Sbjct: 389 PIDLVKTRMQNQRTSGSFVGEVMYKNSLDCFKKVVKFEGLLGLYRGLLPQIVGVAPEKAI 448 Query: 269 SYSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGS 448 + +Y++ P GE ++ G G T PL++VK RL T Q + Sbjct: 449 KLTMNDYMRDKFTKDGKIPLY--GE-IIAGGTGGMCQVVFTNPLEIVKIRLQTAGEVQQA 505 Query: 449 RTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARL 586 +G V+ E G +GL +G L F+AI + A+ A+L Sbjct: 506 GKKIGVF-TVLKELGFLGLYKGSRACFLRDIPFSAIYFPAYAHAKL 550 Score = 42.0 bits (97), Expect = 0.002 Identities = 26/75 (34%), Positives = 42/75 (56%), Gaps = 6/75 (8%) Frame = +2 Query: 350 LCGALAGAISAGLTTPLDVVKTRLMTR------VGAQGSRTVVGTMQEVIAEEGLMGLSR 511 L G++AGA A P+D+VKTR+ + VG + + ++V+ EGL+GL R Sbjct: 374 LLGSVAGACGATAVYPIDLVKTRMQNQRTSGSFVGEVMYKNSLDCFKKVVKFEGLLGLYR 433 Query: 512 GIGPRVLHSACFAAI 556 G+ P+++ A AI Sbjct: 434 GLLPQIVGVAPEKAI 448
>MRS3_YEAST (P10566) Mitochondrial RNA-splicing protein MRS3| Length = 314 Score = 72.0 bits (175), Expect = 1e-12 Identities = 54/173 (31%), Positives = 81/173 (46%), Gaps = 11/173 (6%) Frame = +2 Query: 110 MVPKELITQRLQSGAATGRSWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEY 289 M P + I QR+Q + WQ QI Q++G Y Y TL+ N+P ++ +E Sbjct: 148 MNPFDTIKQRIQLNTSAS-VWQTTKQIYQSEGLAAFYYSYPTTLVMNIPFAAFNFVIYES 206 Query: 290 LKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTV---- 457 F L+ SN N P LCG+++G+ A +TTPLD +KT L R GS+TV Sbjct: 207 STKF-LNPSNEYN--PLIHCLCGSISGSTCAAITTPLDCIKTVLQIR----GSQTVSLEI 259 Query: 458 -------VGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMIL 595 + G G RG PR++ + AI + A+E A+ ++ Sbjct: 260 MRKADTFSKAASAIYQVYGWKGFWRGWKPRIVANMPATAISWTAYECAKHFLM 312 Score = 52.8 bits (125), Expect = 9e-07 Identities = 38/161 (23%), Positives = 71/161 (44%), Gaps = 4/161 (2%) Frame = +2 Query: 110 MVPKELITQRLQSGAATGRSWQVLLQ----ILQTDGFFGLYAGYAATLLRNLPAGVLSYS 277 M P + + R+QS A S + +L I ++G L+ G + +L PA + + Sbjct: 51 MFPIDALKTRIQSANAKSLSAKNMLSQISHISTSEGTLALWKGVQSVILGAGPAHAVYFG 110 Query: 278 SFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTV 457 ++E+ K + S+ P ++ + GA A S L P D +K R+ A +V Sbjct: 111 TYEFCKKNLIDSSDTQTHHPFKTAISGACATTASDALMNPFDTIKQRIQLNTSA----SV 166 Query: 458 VGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETA 580 T +++ EGL ++ + FAA + +E++ Sbjct: 167 WQTTKQIYQSEGLAAFYYSYPTTLVMNIPFAAFNFVIYESS 207 Score = 34.7 bits (78), Expect = 0.25 Identities = 20/101 (19%), Positives = 49/101 (48%), Gaps = 1/101 (0%) Frame = +2 Query: 347 VLCGALAGAISAGLTTPLDVVKTRLMT-RVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGP 523 ++ GA AG + + P+D +KTR+ + + ++ ++ + + EG + L +G+ Sbjct: 37 LIAGAFAGIMEHSVMFPIDALKTRIQSANAKSLSAKNMLSQISHISTSEGTLALWKGVQS 96 Query: 524 RVLHSACFAAIGYCAFETARLMILKSYLESCERKAADEMKT 646 +L + A+ + +E + K+ ++S + + KT Sbjct: 97 VILGAGPAHAVYFGTYEFCK----KNLIDSSDTQTHHPFKT 133
>CMC1_DROME (Q9VA73) Calcium-binding mitochondrial carrier Aralar1| Length = 695 Score = 71.2 bits (173), Expect = 2e-12 Identities = 51/150 (34%), Positives = 76/150 (50%), Gaps = 8/150 (5%) Frame = +2 Query: 116 PKELITQRLQSGA--ATG---RSWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSS 280 P E++ RLQ A+G R+W V+ ++ G FGLY G A LLR++P + + + Sbjct: 461 PLEIVKIRLQVAGEIASGSKIRAWSVVREL----GLFGLYKGARACLLRDVPFSAIYFPT 516 Query: 281 FEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVV 460 + + KA K + P + GA+AG +A L TP DV+KTRL V G T Sbjct: 517 YAHTKAMMADKDGYNH--PLTLLAAGAIAGVPAASLVTPADVIKTRLQV-VARSGQTTYT 573 Query: 461 G---TMQEVIAEEGLMGLSRGIGPRVLHSA 541 G ++++AEEG +G RV S+ Sbjct: 574 GVWDATKKIMAEEGPRAFWKGTAARVFRSS 603 Score = 55.5 bits (132), Expect = 1e-07 Identities = 45/168 (26%), Positives = 72/168 (42%), Gaps = 9/168 (5%) Frame = +2 Query: 116 PKELITQRLQSGAATG--------RSWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLS 271 P +L+ R+Q+ A SW ++++ +GF GLY G L+ P + Sbjct: 362 PIDLVKTRMQNQRAGSYIGEVAYRNSWDCFKKVVRHEGFMGLYRGLLPQLMGVAPEKAIK 421 Query: 272 YSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVG-AQGS 448 + + ++ K N+ VL G AGA T PL++VK RL A GS Sbjct: 422 LTVNDLVRDKLTDKKG--NIPTWAEVLAGGCAGASQVVFTNPLEIVKIRLQVAGEIASGS 479 Query: 449 RTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMI 592 + V+ E GL GL +G +L F+AI + + + M+ Sbjct: 480 KI---RAWSVVRELGLFGLYKGARACLLRDVPFSAIYFPTYAHTKAMM 524 Score = 43.9 bits (102), Expect = 4e-04 Identities = 25/72 (34%), Positives = 40/72 (55%), Gaps = 5/72 (6%) Frame = +2 Query: 356 GALAGAISAGLTTPLDVVKTRLMTR-----VGAQGSRTVVGTMQEVIAEEGLMGLSRGIG 520 G+ AGA+ A + P+D+VKTR+ + +G R ++V+ EG MGL RG+ Sbjct: 349 GSFAGAVGATVVYPIDLVKTRMQNQRAGSYIGEVAYRNSWDCFKKVVRHEGFMGLYRGLL 408 Query: 521 PRVLHSACFAAI 556 P+++ A AI Sbjct: 409 PQLMGVAPEKAI 420
>CMC2_MACFA (Q8HXW2) Calcium-binding mitochondrial carrier protein Aralar2| (Mitochondrial aspartate glutamate carrier 2) (Solute carrier family 25 member 13) (Citrin) Length = 674 Score = 71.2 bits (173), Expect = 2e-12 Identities = 47/145 (32%), Positives = 76/145 (52%), Gaps = 3/145 (2%) Frame = +2 Query: 116 PKELITQRLQ-SGAATGRSWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYL 292 P E++ RLQ +G T L +++ GFFG+Y G A LR++P + + + + Sbjct: 448 PLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHA 507 Query: 293 KAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLM--TRVGAQGSRTVVGT 466 +A ++ ++PG +L GA+AG +A L TP DV+KTRL R G V+ Sbjct: 508 RASFANEDG--QVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDC 565 Query: 467 MQEVIAEEGLMGLSRGIGPRVLHSA 541 ++++ EEG L +G RV S+ Sbjct: 566 FKKILREEGPKALWKG-AARVFRSS 589 Score = 53.5 bits (127), Expect = 5e-07 Identities = 42/165 (25%), Positives = 74/165 (44%), Gaps = 9/165 (5%) Frame = +2 Query: 116 PKELITQRLQSGAATG---------RSWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVL 268 P +L+ R+Q+ +TG S+ ++L+ +GFFGLY G LL P + Sbjct: 348 PIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAI 407 Query: 269 SYSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGS 448 + ++++ + K + L +L G AG T PL++VK RL +V + + Sbjct: 408 KLTVNDFVRDKFMHKDGSVPL--AAEILAGGCAGGSQVIFTNPLEIVKIRL--QVAGEIT 463 Query: 449 RTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETAR 583 + V+ + G G+ +G L F+AI + + AR Sbjct: 464 TGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHAR 508 Score = 39.7 bits (91), Expect = 0.008 Identities = 25/73 (34%), Positives = 39/73 (53%), Gaps = 6/73 (8%) Frame = +2 Query: 356 GALAGAISAGLTTPLDVVKTRLMTR------VGAQGSRTVVGTMQEVIAEEGLMGLSRGI 517 G++AGA+ A P+D+VKTR+ + VG + ++V+ EG GL RG+ Sbjct: 335 GSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGL 394 Query: 518 GPRVLHSACFAAI 556 P++L A AI Sbjct: 395 LPQLLGVAPEKAI 407
>MFRN2_BRARE (Q7T292) Mitoferrin-2 (Mitochondrial iron transporter 2) (Solute| carrier family 25 member 28) Length = 376 Score = 70.1 bits (170), Expect = 5e-12 Identities = 52/173 (30%), Positives = 82/173 (47%), Gaps = 10/173 (5%) Frame = +2 Query: 110 MVPKELITQRLQSGAATGRSWQVLLQ-ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFE 286 M P E++ QR+Q + RS ++ + Q +G Y Y L N+P L + ++E Sbjct: 193 MNPTEVVKQRMQMYNSPYRSVLDCMRCVWQREGALAFYRSYTTQLTMNVPFQALHFMTYE 252 Query: 287 YLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVG------AQGS 448 YL+ + + P ++ GALAGAI+A TTPLDV KT L T+ ++ Sbjct: 253 YLQELLNPQRH---YNPSSHMVSGALAGAIAAAATTPLDVCKTLLNTQESLAVDSVSRSG 309 Query: 449 RTVVG---TMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMILK 598 R + G + V GL +G+ RV++ AI + +E + MI K Sbjct: 310 RHITGLGHAFRTVYRLGGLPAYFKGVQARVIYQMPSTAISWSVYEFFKYMITK 362 Score = 33.1 bits (74), Expect = 0.72 Identities = 27/106 (25%), Positives = 50/106 (47%), Gaps = 6/106 (5%) Frame = +2 Query: 293 KAFALSKSNAPNLTPGES----VLCGALAGAISAGLTTPLDVVKTRL--MTRVGAQGSRT 454 +A LS+ + L G S +L GA+AG + L P+D VKTR+ + A R Sbjct: 59 EASDLSEPDYEGLPQGASTSTHMLAGAVAGIMEHCLMFPIDCVKTRMQSLQPEPAARYRN 118 Query: 455 VVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMI 592 V+ + ++ EG+ RG+ + + A+ + +E + ++ Sbjct: 119 VMDALWRIMRTEGIWRPIRGLNITAVGAGPAHALYFACYERLKKVL 164
>GDC_MOUSE (Q8C0K5) Grave disease carrier protein homolog (GDC) (Mitochondrial| solute carrier protein homolog) (Solute carrier family 25 member 16) Length = 332 Score = 69.7 bits (169), Expect = 7e-12 Identities = 41/137 (29%), Positives = 70/137 (51%), Gaps = 2/137 (1%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 358 L + Q +G+ GLY G A ++R P G + + +FE+ K F +K ++ G Sbjct: 80 LRAVPQKEGYLGLYKGNGAMMIRIFPYGAIQFMAFEHYKTFITTKLGVSGHV--HRLMAG 137 Query: 359 ALAGAISAGLTTPLDVVKTRLMTRV-GAQGSRTVVGTMQEVIAEE-GLMGLSRGIGPRVL 532 ++AG + T PLDVV+ RL +V G ++ + + A+E G +G RG+ P +L Sbjct: 138 SMAGMTAVICTYPLDVVRVRLAFQVKGEHTYSGIIHAFKTIYAKEGGFLGFYRGLMPTIL 197 Query: 533 HSACFAAIGYCAFETAR 583 A +A + + F T + Sbjct: 198 GMAPYAGVSFFTFGTLK 214 Score = 51.6 bits (122), Expect = 2e-06 Identities = 42/142 (29%), Positives = 68/142 (47%), Gaps = 18/142 (12%) Frame = +2 Query: 203 GFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALS---------KSNAPN---LTPGES 346 GF G Y G T+L P +S+ +F LK+ LS S+ PN L + Sbjct: 184 GFLGFYRGLMPTILGMAPYAGVSFFTFGTLKSVGLSYAPALLGRPSSDNPNVLVLKTHIN 243 Query: 347 VLCGALAGAISAGLTTPLDVVKTRLMTRVGA-----QGSRTVVGTMQEVIAEEGL-MGLS 508 +LCG +AGAI+ ++ P DV + R+ ++GA + T+ TM+ V + G+ GL Sbjct: 244 LLCGGVAGAIAQTISYPFDVTRRRM--QLGAVLPEFEKCLTMRETMKYVYGQHGIRRGLY 301 Query: 509 RGIGPRVLHSACFAAIGYCAFE 574 RG+ + A+ + +E Sbjct: 302 RGLSLNYIRCIPSQAVAFTTYE 323 Score = 41.6 bits (96), Expect = 0.002 Identities = 26/83 (31%), Positives = 39/83 (46%) Frame = +2 Query: 344 SVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGP 523 S L G +AG + PLD VK L V+ T++ V +EG +GL +G G Sbjct: 39 SFLAGGIAGCCAKTTVAPLDRVKVLLQAHNRHYKHLGVLSTLRAVPQKEGYLGLYKGNGA 98 Query: 524 RVLHSACFAAIGYCAFETARLMI 592 ++ + AI + AFE + I Sbjct: 99 MMIRIFPYGAIQFMAFEHYKTFI 121
>MFRN2_MOUSE (Q8R0Z5) Mitoferrin-2 (Mitochondrial iron transporter 2) (Solute| carrier family 25 member 28) (Mitochondrial RNA splicing protein 3/4 homolog) (MRS3/4) Length = 364 Score = 69.7 bits (169), Expect = 7e-12 Identities = 48/171 (28%), Positives = 77/171 (45%), Gaps = 8/171 (4%) Frame = +2 Query: 110 MVPKELITQRLQS-GAATGRSWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFE 286 M P E++ QR+Q + R + + Q +G Y Y L N+P + + ++E Sbjct: 188 MNPAEVVKQRMQMYNSPYHRVTDCVRAVWQNEGAGAFYRSYTTQLTMNVPFQAIHFMTYE 247 Query: 287 YLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVG- 463 +L+ + P VLCGA AGA++A TTPLDV KT L T+ + + G Sbjct: 248 FLQEHFNPQRR---YNPSSHVLCGACAGAVAAAATTPLDVCKTLLNTQESLALNSNITGH 304 Query: 464 ------TMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMILK 598 + V G+ RG+ RV++ AI + +E + +I K Sbjct: 305 ITGMASAFRTVYQVGGVTAYFRGVQARVIYQIPSTAIAWSVYEFFKYLITK 355 Score = 30.4 bits (67), Expect = 4.7 Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 10/77 (12%) Frame = +2 Query: 347 VLCGALAGAISAGLTTPLDVVKTRLMTRV--GAQGSRTVVGTMQEVIAEEGLMGLSRGI- 517 ++ GA+AG + + P+D VKTR+ + A R V+ + ++ EGL RG+ Sbjct: 76 MVAGAVAGILEHCVMYPIDCVKTRMQSLQPDPAARYRNVLEALWRIMRTEGLWRPMRGLN 135 Query: 518 ------GP-RVLHSACF 547 GP L+ AC+ Sbjct: 136 VTATGAGPAHALYFACY 152
>MFRN1_MOUSE (Q920G8) Mitoferrin-1 (Mitochondrial iron transporter 1) (Solute| carrier family 25 member 37) (Mitochondria solute carrier protein) Length = 338 Score = 69.3 bits (168), Expect = 9e-12 Identities = 49/177 (27%), Positives = 83/177 (46%), Gaps = 9/177 (5%) Frame = +2 Query: 110 MVPKELITQRLQSGAATGRS-WQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFE 286 M P E++ QRLQ + +S + + + +T+G Y Y L N+P + + ++E Sbjct: 161 MNPAEVVKQRLQMYNSQHQSAFSCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYE 220 Query: 287 YLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRT---- 454 +L+ + + P ++ G LAGA++A TTPLDV KT L T+ S Sbjct: 221 FLQEQVNPRRD---YNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENMALSLANVSG 277 Query: 455 ----VVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMILKSYLES 613 + + V GL G +GI RV++ AI + +E + ++ K LE+ Sbjct: 278 RLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYILTKRQLEN 334 Score = 31.6 bits (70), Expect = 2.1 Identities = 18/78 (23%), Positives = 39/78 (50%), Gaps = 2/78 (2%) Frame = +2 Query: 356 GALAGAISAGLTTPLDVVKTRLMTRVGAQGSR--TVVGTMQEVIAEEGLMGLSRGIGPRV 529 GA+AG + + P+D VKTR+ + +R ++ G ++ ++ EG RG+ + Sbjct: 52 GAMAGILEHSIMYPVDSVKTRMQSLNPDPKARYTSIYGALKRIMHTEGFWRPLRGLNVMM 111 Query: 530 LHSACFAAIGYCAFETAR 583 + + A+ + +E + Sbjct: 112 MGAGPAHAMYFACYENMK 129
>YM39_YEAST (Q03829) Putative mitochondrial carrier YMR166C| Length = 368 Score = 68.2 bits (165), Expect = 2e-11 Identities = 50/183 (27%), Positives = 88/183 (48%), Gaps = 35/183 (19%) Frame = +2 Query: 113 VPKELITQRLQ-----------SGAATGRSWQVLLQILQTDGFFGLYAGYAATLLRNLPA 259 VP E++ RLQ SG + +++ +GF L+ GY ATL R+LP Sbjct: 167 VPSEVLKTRLQLQGRFNNPFFQSGYNYSNLRNAIKTVIKEEGFRSLFFGYKATLARDLPF 226 Query: 260 GVLSYSSFEYLK--AFALSKSNAPN--LTPGESVLCGALAGAISAGLTTPLDVVKTRLMT 427 L ++ +E + AF + + + + L+ +L GA AG ++ +TTP+DVVKTR+ T Sbjct: 227 SALQFAFYEKFRQLAFKIEQKDGRDGELSIPNEILTGACAGGLAGIITTPMDVVKTRVQT 286 Query: 428 RV--------------------GAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACF 547 + A S ++ +++ V EG++G G+GPR + ++ Sbjct: 287 QQPPSQSNKSYSVTHPHVTNGRPAALSNSISLSLRTVYQSEGVLGFFSGVGPRFVWTSVQ 346 Query: 548 AAI 556 ++I Sbjct: 347 SSI 349 Score = 44.3 bits (103), Expect = 3e-04 Identities = 34/137 (24%), Positives = 57/137 (41%), Gaps = 8/137 (5%) Frame = +2 Query: 212 GLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLT 391 GLY GY A +L + P+ + + ++EY K + + S G L IS+ + Sbjct: 109 GLYGGYMAAMLGSFPSAAIFFGTYEYTKRTMIEDWQINDTITHLS--AGFLGDFISSFVY 166 Query: 392 TPLDVVKTRLMTR--------VGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACF 547 P +V+KTRL + + ++ VI EEG L G + F Sbjct: 167 VPSEVLKTRLQLQGRFNNPFFQSGYNYSNLRNAIKTVIKEEGFRSLFFGYKATLARDLPF 226 Query: 548 AAIGYCAFETARLMILK 598 +A+ + +E R + K Sbjct: 227 SALQFAFYEKFRQLAFK 243 Score = 32.3 bits (72), Expect = 1.2 Identities = 27/84 (32%), Positives = 38/84 (45%), Gaps = 2/84 (2%) Frame = +2 Query: 347 VLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGL-MGLSRGIGP 523 V+ G + G I LD VKTR + R ++ + + EEG+ GL G Sbjct: 57 VVSGGIGGKIGDSAMHSLDTVKTRQQGAPNVKKYRNMISAYRTIWLEEGVRRGLYGGYMA 116 Query: 524 RVLHSACFAAIGYCAFE-TARLMI 592 +L S AAI + +E T R MI Sbjct: 117 AMLGSFPSAAIFFGTYEYTKRTMI 140
>MFRN1_RAT (Q66H23) Mitoferrin-1 (Mitochondrial iron transporter 1) (Solute| carrier family 25 member 37) Length = 338 Score = 67.8 bits (164), Expect = 3e-11 Identities = 49/177 (27%), Positives = 81/177 (45%), Gaps = 9/177 (5%) Frame = +2 Query: 110 MVPKELITQRLQSGAATGRS-WQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFE 286 M P E++ QRLQ + +S + + +T+G Y Y L N+P + + ++E Sbjct: 161 MNPAEVVKQRLQMYNSQHQSALSCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYE 220 Query: 287 YLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRT---- 454 +L+ + + P ++ G LAGA++A TTPLDV KT L T+ S Sbjct: 221 FLQEQVNPRRD---YNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENMALSLANVSG 277 Query: 455 ----VVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMILKSYLES 613 + + V GL G +GI RV++ AI + +E + + K LE+ Sbjct: 278 RLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFLTKRQLEN 334 Score = 31.6 bits (70), Expect = 2.1 Identities = 18/78 (23%), Positives = 39/78 (50%), Gaps = 2/78 (2%) Frame = +2 Query: 356 GALAGAISAGLTTPLDVVKTRLMTRVGAQGSR--TVVGTMQEVIAEEGLMGLSRGIGPRV 529 GA+AG + + P+D VKTR+ + +R ++ G ++ ++ EG RG+ + Sbjct: 52 GAMAGILEHSIMYPVDSVKTRMQSLNPDPKARYTSIYGALKRIMHTEGFWRPLRGLNVMM 111 Query: 530 LHSACFAAIGYCAFETAR 583 + + A+ + +E + Sbjct: 112 MGAGPAHAMYFACYENMK 129
>AGC1_YEAST (Q12482) Mitochondrial aspartate-glutamate transporter AGC1| (Aspartate-glutamate carrier 1) Length = 902 Score = 67.4 bits (163), Expect = 3e-11 Identities = 53/182 (29%), Positives = 85/182 (46%), Gaps = 12/182 (6%) Frame = +2 Query: 116 PKELITQRLQS-----GAATGRSWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSS 280 P E++ RLQ G ++ + QI++ G GLY G AA L+R++P + + + Sbjct: 644 PLEIVKIRLQVQSDYVGENIQQANETATQIVKKLGLRGLYNGVAACLMRDVPFSAIYFPT 703 Query: 281 FEYLKAFALS-----KSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLM--TRVGA 439 + +LK K+ L E + GA+AG +A LTTP DV+KTRL R G Sbjct: 704 YAHLKKDLFDFDPNDKTKRNRLKTWELLTAGAIAGMPAAFLTTPFDVIKTRLQIDPRKGE 763 Query: 440 QGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMILKSYLESCE 619 + ++ ++ EE +G G RVL S+ A+E + K ++ S + Sbjct: 764 TKYNGIFHAIRTILKEESFRSFFKGGGARVLRSSPQFGFTLAAYE-----LFKGFIPSPD 818 Query: 620 RK 625 K Sbjct: 819 NK 820 Score = 55.8 bits (133), Expect = 1e-07 Identities = 40/152 (26%), Positives = 72/152 (47%), Gaps = 5/152 (3%) Frame = +2 Query: 116 PKELITQRLQSGAATGR---SWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFE 286 P + I R+Q+ + + S LL+I+ +G GLY+G L+ P + + + Sbjct: 550 PIDFIKTRMQAQRSLAQYKNSIDCLLKIISREGIKGLYSGLGPQLIGVAPEKAIKLTVND 609 Query: 287 YLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGS--RTVV 460 +++ K+ +L P ++ GA AGA T PL++VK RL + G + Sbjct: 610 FMRNRLTDKNGKLSLFP--EIISGASAGACQVIFTNPLEIVKIRLQVQSDYVGENIQQAN 667 Query: 461 GTMQEVIAEEGLMGLSRGIGPRVLHSACFAAI 556 T +++ + GL GL G+ ++ F+AI Sbjct: 668 ETATQIVKKLGLRGLYNGVAACLMRDVPFSAI 699 Score = 45.1 bits (105), Expect = 2e-04 Identities = 21/67 (31%), Positives = 39/67 (58%) Frame = +2 Query: 356 GALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLH 535 G++AG I A + P+D +KTR+ + + + + ++I+ EG+ GL G+GP+++ Sbjct: 537 GSIAGCIGATVVYPIDFIKTRMQAQRSLAQYKNSIDCLLKIISREGIKGLYSGLGPQLIG 596 Query: 536 SACFAAI 556 A AI Sbjct: 597 VAPEKAI 603
>CMC1_MOUSE (Q8BH59) Calcium-binding mitochondrial carrier protein Aralar1| (Mitochondrial aspartate glutamate carrier 1) (Solute carrier family 25 member 12) Length = 677 Score = 67.0 bits (162), Expect = 5e-11 Identities = 49/146 (33%), Positives = 71/146 (48%), Gaps = 4/146 (2%) Frame = +2 Query: 116 PKELITQRLQ-SGAATGRSWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYL 292 P E++ RLQ +G T L +LQ G FGLY G A LR++P + + + + Sbjct: 446 PLEIVKIRLQVAGEITTGPRVSALNVLQDLGLFGLYKGAKACFLRDIPFSAIYFPVYAHC 505 Query: 293 KAFALSKSNAPNLTPGESVL-CGALAGAISAGLTTPLDVVKTRLM--TRVGAQGSRTVVG 463 K ++ G ++L GALAG +A L TP DV+KTRL R G VV Sbjct: 506 KLLLADENGRVG---GINLLTAGALAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVVD 562 Query: 464 TMQEVIAEEGLMGLSRGIGPRVLHSA 541 ++++ EEG +G RV S+ Sbjct: 563 CFRKILREEGPSAFWKGTAARVFRSS 588 Score = 53.5 bits (127), Expect = 5e-07 Identities = 43/168 (25%), Positives = 77/168 (45%), Gaps = 9/168 (5%) Frame = +2 Query: 116 PKELITQRLQSGAATG---------RSWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVL 268 P +L+ R+Q+ TG S+ ++L+ +GFFGLY G L+ P + Sbjct: 346 PIDLVKTRMQNQRGTGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAI 405 Query: 269 SYSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGS 448 + ++++ +K + P E +L G AG T PL++VK RL +V + + Sbjct: 406 KLTVNDFVRD-KFTKRDGSIPLPAE-ILAGGCAGGSQVIFTNPLEIVKIRL--QVAGEIT 461 Query: 449 RTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMI 592 + V+ + GL GL +G L F+AI + + +L++ Sbjct: 462 TGPRVSALNVLQDLGLFGLYKGAKACFLRDIPFSAIYFPVYAHCKLLL 509 Score = 41.2 bits (95), Expect = 0.003 Identities = 26/76 (34%), Positives = 44/76 (57%), Gaps = 9/76 (11%) Frame = +2 Query: 356 GALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTM---------QEVIAEEGLMGLS 508 G++AGA+ A P+D+VKTR+ + +G+ +VVG + ++V+ EG GL Sbjct: 333 GSVAGAVGATAVYPIDLVKTRMQNQ---RGTGSVVGELMYKNSFDCFKKVLRYEGFFGLY 389 Query: 509 RGIGPRVLHSACFAAI 556 RG+ P+++ A AI Sbjct: 390 RGLIPQLIGVAPEKAI 405
>GDC_RAT (P16261) Grave disease carrier protein (GDC) (Mitochondrial solute| carrier protein homolog) (Solute carrier family 25 member 16) (Fragment) Length = 322 Score = 67.0 bits (162), Expect = 5e-11 Identities = 42/140 (30%), Positives = 72/140 (51%), Gaps = 5/140 (3%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 358 L + Q +G+ GLY G A ++R P G + + +FE+ K F +K ++ G Sbjct: 80 LRAVPQKEGYLGLYKGNGAMMIRIFPYGAIQFMAFEHYKTFITTKLGVSGHV--HRLMAG 137 Query: 359 ALAGAISAG---LTTPLDVVKTRLMTRV-GAQGSRTVVGTMQEVIAEE-GLMGLSRGIGP 523 ++AG +S T PLDVV+ RL +V G ++ + + A+E G +G RG+ P Sbjct: 138 SMAGKMSMTAVICTYPLDVVRVRLAFQVKGEHTYSGIIHAFKTIYAKEGGFLGFYRGLMP 197 Query: 524 RVLHSACFAAIGYCAFETAR 583 +L A +A++ + F T + Sbjct: 198 TILGMAPYASVSFFTFGTLK 217 Score = 45.4 bits (106), Expect = 1e-04 Identities = 39/123 (31%), Positives = 60/123 (48%), Gaps = 18/123 (14%) Frame = +2 Query: 203 GFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALS---------KSNAPN---LTPGES 346 GF G Y G T+L P +S+ +F LK+ LS S+ PN L + Sbjct: 187 GFLGFYRGLMPTILGMAPYASVSFFTFGTLKSVGLSYAPTLLGRPSSDNPNVLVLKTHIN 246 Query: 347 VLCGALAGAISAGLTTPLDVVKTRLMTRVGA-----QGSRTVVGTMQEVIAEEGL-MGLS 508 +LCG +A AI+ ++ P DV + R+ ++GA + T+ TM+ V G+ GL Sbjct: 247 LLCGGVARAIAQTISYPFDVTRRRM--QLGAVLPEFEKCLTMRETMKYVYGHHGIRRGLY 304 Query: 509 RGI 517 RG+ Sbjct: 305 RGL 307 Score = 39.7 bits (91), Expect = 0.008 Identities = 25/83 (30%), Positives = 39/83 (46%) Frame = +2 Query: 344 SVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGP 523 S L G++AG + PLD VK L V+ ++ V +EG +GL +G G Sbjct: 39 SFLAGSIAGCCAKTTVAPLDRVKVLLQAHNHHYKHLGVLSPLRAVPQKEGYLGLYKGNGA 98 Query: 524 RVLHSACFAAIGYCAFETARLMI 592 ++ + AI + AFE + I Sbjct: 99 MMIRIFPYGAIQFMAFEHYKTFI 121
>GDC_HUMAN (P16260) Grave disease carrier protein (GDC) (Grave disease| autoantigen) (GDA) (Mitochondrial solute carrier protein homolog) (Solute carrier family 25 member 16) Length = 332 Score = 66.6 bits (161), Expect = 6e-11 Identities = 39/140 (27%), Positives = 70/140 (50%), Gaps = 2/140 (1%) Frame = +2 Query: 170 WQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESV 349 + L + Q +GF GLY G A ++R P G + + +FE+ K +K + Sbjct: 77 FSALRAVPQKEGFLGLYKGNGAMMIRIFPYGAIQFMAFEHYKTLITTKLGISGHV--HRL 134 Query: 350 LCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRT-VVGTMQEVIAEE-GLMGLSRGIGP 523 + G++AG + T P+D+V+ RL +V + T ++ + + A+E G G RG+ P Sbjct: 135 MAGSMAGMTAVICTDPVDMVRVRLAFQVKGEHRYTGIIHAFKTIYAKEGGFFGFYRGLMP 194 Query: 524 RVLHSACFAAIGYCAFETAR 583 +L A +A + + F T + Sbjct: 195 TILGMAPYAGVSFFTFGTLK 214 Score = 46.6 bits (109), Expect = 6e-05 Identities = 39/140 (27%), Positives = 62/140 (44%), Gaps = 16/140 (11%) Frame = +2 Query: 203 GFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALS---------KSNAPN---LTPGES 346 GFFG Y G T+L P +S+ +F LK+ LS S+ PN L + Sbjct: 184 GFFGFYRGLMPTILGMAPYAGVSFFTFGTLKSVGLSHAPTLLGSPSSDNPNVLVLKTHVN 243 Query: 347 VLCGALAGAISAGLTTPLDVVKTRLMTRV---GAQGSRTVVGTMQEVIAEEGL-MGLSRG 514 +LCG +A AI+ ++ P DV + R+ + T+ TM+ G+ GL RG Sbjct: 244 LLCGGVARAIAQTISYPFDVTRRRMQLGTVLPEFEKCLTMRDTMKYDYGHHGIRKGLYRG 303 Query: 515 IGPRVLHSACFAAIGYCAFE 574 + + A+ + +E Sbjct: 304 LSLNYIRCIPSQAVAFTTYE 323 Score = 40.4 bits (93), Expect = 0.005 Identities = 25/83 (30%), Positives = 39/83 (46%) Frame = +2 Query: 344 SVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGP 523 S L G++AG + PLD VK L V ++ V +EG +GL +G G Sbjct: 39 SFLAGSIAGCCAKTTVAPLDRVKVLLQAHNHHYKHLGVFSALRAVPQKEGFLGLYKGNGA 98 Query: 524 RVLHSACFAAIGYCAFETARLMI 592 ++ + AI + AFE + +I Sbjct: 99 MMIRIFPYGAIQFMAFEHYKTLI 121
>ORNT2_HUMAN (Q9BXI2) Mitochondrial ornithine transporter 2 (Solute carrier| family 25 member 2) Length = 301 Score = 66.6 bits (161), Expect = 6e-11 Identities = 46/175 (26%), Positives = 83/175 (47%), Gaps = 12/175 (6%) Frame = +2 Query: 110 MVPKELITQRLQS----------GAATGRSWQVLLQILQTDGFFGLYAGYAATLLRNLPA 259 + P EL+ RLQ+ + W V+ IL+ DG G Y G ++TLL+ P Sbjct: 124 LCPTELVKCRLQTMYEMEMSGKIAKSHNTIWSVVKGILKKDGPLGFYHGLSSTLLQEGPG 183 Query: 260 GVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRL--MTRV 433 + +E ++F S + L P +L G +AG + P+D +K+R+ ++ Sbjct: 184 YFFFFGGYELSRSFFASGRSKDELGPVHLMLSGGVAGICLWLIVFPVDCIKSRIQVLSMY 243 Query: 434 GAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMILK 598 G Q +GT+ V+ EG++ L G+ ++ + + A+E +R M++K Sbjct: 244 GKQAG--FIGTLLSVVRNEGIVALYSGLKATMIRAIPANGALFVAYEYSRKMMMK 296 Score = 35.8 bits (81), Expect = 0.11 Identities = 19/72 (26%), Positives = 37/72 (51%), Gaps = 3/72 (4%) Frame = +2 Query: 116 PKELITQRLQSGAATGRSWQ---VLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFE 286 P + I R+Q + G+ LL +++ +G LY+G AT++R +PA + ++E Sbjct: 229 PVDCIKSRIQVLSMYGKQAGFIGTLLSVVRNEGIVALYSGLKATMIRAIPANGALFVAYE 288 Query: 287 YLKAFALSKSNA 322 Y + + + A Sbjct: 289 YSRKMMMKQLEA 300
>GDC_BOVIN (Q01888) Grave disease carrier protein (GDC) (Mitochondrial solute| carrier protein homolog) (Solute carrier family 25 member 16) Length = 330 Score = 66.6 bits (161), Expect = 6e-11 Identities = 38/140 (27%), Positives = 72/140 (51%), Gaps = 2/140 (1%) Frame = +2 Query: 170 WQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESV 349 + L + + +G+ GLY G A ++R P G + + +FE+ K +K + Sbjct: 75 FSTLRAVPKKEGYLGLYKGNGAMMIRIFPYGAIQFMAFEHYKTLITTKLGVSGHV--HRL 132 Query: 350 LCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRT-VVGTMQEVIAEE-GLMGLSRGIGP 523 + G++AG + T PLD+V+ RL +V + + T ++ + + A+E G +G RG+ P Sbjct: 133 MAGSMAGMTAVICTYPLDMVRVRLAFQVKGEHTYTGIIHAFKTIYAKEGGFLGFYRGLMP 192 Query: 524 RVLHSACFAAIGYCAFETAR 583 +L A +A + + F T + Sbjct: 193 TILGMAPYAGVSFFTFGTLK 212 Score = 51.2 bits (121), Expect = 3e-06 Identities = 42/142 (29%), Positives = 67/142 (47%), Gaps = 18/142 (12%) Frame = +2 Query: 203 GFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALS---------KSNAPN---LTPGES 346 GF G Y G T+L P +S+ +F LK+ LS S+ PN L + Sbjct: 182 GFLGFYRGLMPTILGMAPYAGVSFFTFGTLKSVGLSYAPTLLGRPSSDNPNVLVLKTHIN 241 Query: 347 VLCGALAGAISAGLTTPLDVVKTRLMTRVGA-----QGSRTVVGTMQEVIAEEGL-MGLS 508 +LCG +AGAI+ ++ P DV + R+ ++GA + T+ TM+ V G+ GL Sbjct: 242 LLCGGVAGAIAQTISYPFDVTRRRM--QLGAVLPEFEKCLTMRETMKYVYGHHGIRKGLY 299 Query: 509 RGIGPRVLHSACFAAIGYCAFE 574 RG+ + A+ + +E Sbjct: 300 RGLSLNYIRCVPSQAVAFTTYE 321 Score = 41.6 bits (96), Expect = 0.002 Identities = 26/83 (31%), Positives = 39/83 (46%) Frame = +2 Query: 344 SVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGP 523 S L G +AG + PLD VK L V T++ V +EG +GL +G G Sbjct: 37 SFLAGGIAGCCAKTTVAPLDRVKVLLQAHNHHYRHLGVFSTLRAVPKKEGYLGLYKGNGA 96 Query: 524 RVLHSACFAAIGYCAFETARLMI 592 ++ + AI + AFE + +I Sbjct: 97 MMIRIFPYGAIQFMAFEHYKTLI 119
>MCAT_ARATH (Q93XM7) Mitochondrial carnitine/acylcarnitine carrier-like protein| (Protein A BOUT DE SOUFFLE) (Carnitine/acylcarnitine translocase-like protein) (CAC-like protein) Length = 300 Score = 66.6 bits (161), Expect = 6e-11 Identities = 52/175 (29%), Positives = 83/175 (47%), Gaps = 19/175 (10%) Frame = +2 Query: 116 PKELITQRLQS-----GAAT----------GRSWQVLLQILQTDGFF-GLYAGYAATLLR 247 P ELI RLQ+ GA+T G V +L+++G GL+ G T R Sbjct: 124 PTELIKCRLQAQGALAGASTTSSVVAAVKYGGPMDVARHVLRSEGGARGLFKGLFPTFAR 183 Query: 248 NLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMT 427 +P ++++E K F S+ +L G ++ G +AGA G+ P DVVK+ L Sbjct: 184 EVPGNATMFAAYEAFKRFLAGGSDTSSLGQGSLIMAGGVAGASFWGIVYPTDVVKSVL-- 241 Query: 428 RVGAQGSRTVVGTM---QEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETAR 583 +V + G+M ++++ EG+ GL +G GP + S A + A+E R Sbjct: 242 QVDDYKNPRYTGSMDAFRKILKSEGVKGLYKGFGPAMARSVPANAACFLAYEMTR 296 Score = 30.8 bits (68), Expect = 3.6 Identities = 12/44 (27%), Positives = 25/44 (56%) Frame = +2 Query: 167 SWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKA 298 S +IL+++G GLY G+ + R++PA + ++E ++ Sbjct: 254 SMDAFRKILKSEGVKGLYKGFGPAMARSVPANAACFLAYEMTRS 297
>MFRN_CAEEL (Q23125) Mitoferrin| Length = 312 Score = 66.2 bits (160), Expect = 8e-11 Identities = 45/176 (25%), Positives = 80/176 (45%), Gaps = 15/176 (8%) Frame = +2 Query: 110 MVPKELITQRLQSGAAT-GRSWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFE 286 M P E++ QR+Q + G S + + +G Y Y L N+P + + S+E Sbjct: 132 MNPAEVVKQRMQMAFSPYGSSLECARCVYNREGVAAFYRSYTTQLAMNVPFQAIHFMSYE 191 Query: 287 YLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGS------ 448 + + L+ + P ++ G LAG ++A LTTP+D VKT L T+ A+ Sbjct: 192 FWQ-HVLNPEH--KYDPKSHLIAGGLAGGLAAALTTPMDCVKTVLNTQQAAEADPANRRI 248 Query: 449 --------RTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMI 592 R + ++ + ++ GL G S G+ RV+ A+ + +E + M+ Sbjct: 249 FLQARYRYRGISDAVRTIYSQRGLSGFSCGLQARVIFQVPATALSWSVYELFKFML 304 Score = 32.7 bits (73), Expect = 0.94 Identities = 24/86 (27%), Positives = 40/86 (46%), Gaps = 2/86 (2%) Frame = +2 Query: 356 GALAGAISAGLTTPLDVVKTRLMTRVGAQGSR--TVVGTMQEVIAEEGLMGLSRGIGPRV 529 GALAGA+ + P D VKTR+ + ++ T V ++ ++ EG + RG+ Sbjct: 24 GALAGAVEHCVMFPFDSVKTRMQSLCPCPETKCPTPVHSLMSIVKREGWLRPLRGVNAVA 83 Query: 530 LHSACFAAIGYCAFETARLMILKSYL 607 S A+ + +E +K YL Sbjct: 84 AGSMPAHALYFTVYEK-----MKGYL 104
>GHC2_RAT (Q505J6) Mitochondrial glutamate carrier 2 (GC-2) (Glutamate/H(+)| symporter 2) (Solute carrier family 25 member 18) Length = 315 Score = 65.9 bits (159), Expect = 1e-10 Identities = 40/119 (33%), Positives = 62/119 (52%), Gaps = 3/119 (2%) Frame = +2 Query: 185 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGAL 364 ++L+T G GLY G ATLLR++P ++ + F L +S+ + S + G Sbjct: 172 ELLRTQGLSGLYRGLGATLLRDIPFSIIYFPLFANLNQLGVSELTG-KASFTHSFVAGCA 230 Query: 365 AGAISAGLTTPLDVVKTRLMT---RVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVL 532 AG++SA TPLDV+KTR+ T +G R V +++ +EG +G G R L Sbjct: 231 AGSVSAVAVTPLDVLKTRIQTLKKGLGEDTYRGVTDCARKLWTQEGAAAFMKGAGCRAL 289 Score = 43.9 bits (102), Expect = 4e-04 Identities = 36/155 (23%), Positives = 64/155 (41%), Gaps = 24/155 (15%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 358 L++ + +GF G+Y G A L P + ++ ++L+ + NL +L G Sbjct: 52 LVKTARAEGFLGMYRGAAVNLTLVTPEKAIKLAANDFLRQLLMQDGTQRNLK--MEMLAG 109 Query: 359 ALAGAISAGLTTPLDVVKTRLM----TRVGAQGSRTVVGTMQ------------------ 472 AG +T P++++K +L V Q S + T + Sbjct: 110 CGAGICQVVITCPMEMLKIQLQDAGRLAVCQQASASATPTSRPYSTGSTSTHRRPSATLI 169 Query: 473 --EVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAF 571 E++ +GL GL RG+G +L F+ I + F Sbjct: 170 AWELLRTQGLSGLYRGLGATLLRDIPFSIIYFPLF 204 Score = 34.3 bits (77), Expect = 0.32 Identities = 16/66 (24%), Positives = 33/66 (50%) Frame = +2 Query: 317 NAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGL 496 ++ +L+ ++ G +AG + P+D+ KTRL + G + + + + EG Sbjct: 2 SSQDLSITAKLINGGIAGLVGVTCVFPIDLAKTRLQNQQGKDVYKGMTDCLVKTARAEGF 61 Query: 497 MGLSRG 514 +G+ RG Sbjct: 62 LGMYRG 67
>BT1_MAIZE (P29518) Protein brittle-1, chloroplast precursor| Length = 436 Score = 65.9 bits (159), Expect = 1e-10 Identities = 46/160 (28%), Positives = 79/160 (49%), Gaps = 2/160 (1%) Frame = +2 Query: 110 MVPKELITQRLQSGAATGRSWQVLLQ-ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFE 286 + P E I L G+ S + Q I+Q +G+ GL+ G A +LR P+ + + +++ Sbjct: 152 VAPLETIRTHLMVGSIGVDSMAGVFQWIMQNEGWTGLFRGNAVNVLRVAPSKAIEHFTYD 211 Query: 287 YLKAFALSKSNAPNLTPGESVL-CGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVG 463 K F K + P P + L GALAG S T P++++KTR+ + V Sbjct: 212 TAKKFLTPKGDEPPKIPIPTPLVAGALAGFASTLCTYPMELIKTRVTIEKDVYDN--VAH 269 Query: 464 TMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETAR 583 +++ +EG L RG+ P ++ +AA + A+ET + Sbjct: 270 AFVKILRDEGPSELYRGLTPSLIGVVPYAACNFYAYETLK 309 Score = 61.6 bits (148), Expect = 2e-09 Identities = 43/156 (27%), Positives = 80/156 (51%), Gaps = 7/156 (4%) Frame = +2 Query: 182 LQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAF---ALSKSNAPNLTPGESVL 352 ++IL+ +G LY G +L+ +P ++ ++E LK A + ++ P ++L Sbjct: 272 VKILRDEGPSELYRGLTPSLIGVVPYAACNFYAYETLKRLYRRATGRRPGADVGPVATLL 331 Query: 353 CGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQE----VIAEEGLMGLSRGIG 520 G+ AGAI++ T PL+V + ++ +VGA G R V + ++ +EG GL RG+G Sbjct: 332 IGSAAGAIASSATFPLEVARKQM--QVGAVGGRQVYQNVLHAIYCILKKEGAGGLYRGLG 389 Query: 521 PRVLHSACFAAIGYCAFETARLMILKSYLESCERKA 628 P + A I + +E + +++ E E +A Sbjct: 390 PSCIKLMPAAGIAFMCYEACKKILVDKEDEEEEDEA 425 Score = 51.2 bits (121), Expect = 3e-06 Identities = 29/79 (36%), Positives = 45/79 (56%) Frame = +2 Query: 347 VLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPR 526 ++ GA+AGA+S PL+ ++T LM VG+ G ++ G Q ++ EG GL RG Sbjct: 138 LVSGAIAGAVSRTFVAPLETIRTHLM--VGSIGVDSMAGVFQWIMQNEGWTGLFRGNAVN 195 Query: 527 VLHSACFAAIGYCAFETAR 583 VL A AI + ++TA+ Sbjct: 196 VLRVAPSKAIEHFTYDTAK 214
>MFRN_CAEBR (Q620A6) Mitoferrin| Length = 311 Score = 65.5 bits (158), Expect = 1e-10 Identities = 42/176 (23%), Positives = 78/176 (44%), Gaps = 15/176 (8%) Frame = +2 Query: 110 MVPKELITQRLQSGAAT-GRSWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFE 286 M P E++ QR+Q + G S + + +GF Y Y L N+P + + +E Sbjct: 131 MNPAEVVKQRMQMAYSPYGSSLECARCVYNREGFAAFYRSYTTQLAMNVPFQAIHFMGYE 190 Query: 287 YLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGS------ 448 + + + P ++ G LAG ++A +TTP+D VKT L T+ A+ Sbjct: 191 FWQQVLNPEHK---YDPKSHLIAGGLAGGLAAAVTTPMDCVKTVLNTQQAAEADPSNRRI 247 Query: 449 --------RTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMI 592 R + ++ + ++ G+ G S G+ RV+ A+ + +E + M+ Sbjct: 248 FLKARYRYRGISDAVRTIYSQRGMAGFSCGLQARVIFQVPATALSWSVYELFKFML 303 Score = 35.8 bits (81), Expect = 0.11 Identities = 32/134 (23%), Positives = 57/134 (42%), Gaps = 2/134 (1%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKS--NAPNLTPGESVL 352 L+ I++ +G+ G A ++PA L ++ +E +K+F + + L G S Sbjct: 62 LMSIVKREGWLRPLRGVNAVAAGSMPAHALYFTVYEKMKSFLTGNTAGHEHTLAYGAS-- 119 Query: 353 CGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVL 532 G +A I + P +VVK R+ GS + + V EG R ++ Sbjct: 120 -GVVATLIHDAVMNPAEVVKQRMQMAYSPYGSS--LECARCVYNREGFAAFYRSYTTQLA 176 Query: 533 HSACFAAIGYCAFE 574 + F AI + +E Sbjct: 177 MNVPFQAIHFMGYE 190 Score = 32.3 bits (72), Expect = 1.2 Identities = 24/85 (28%), Positives = 40/85 (47%), Gaps = 1/85 (1%) Frame = +2 Query: 356 GALAGAISAGLTTPLDVVKTRLMTRVGAQGS-RTVVGTMQEVIAEEGLMGLSRGIGPRVL 532 GALAGA+ + P D VKTR+ + + T V ++ ++ EG + RG+ Sbjct: 24 GALAGAVEHCVMFPFDSVKTRMQSLCPCETKCPTPVHSLMSIVKREGWLRPLRGVNAVAA 83 Query: 533 HSACFAAIGYCAFETARLMILKSYL 607 S A+ + +E +KS+L Sbjct: 84 GSMPAHALYFTVYEK-----MKSFL 103
>ORNT1_MOUSE (Q9WVD5) Mitochondrial ornithine transporter 1 (Solute carrier| family 25 member 15) Length = 301 Score = 65.5 bits (158), Expect = 1e-10 Identities = 44/173 (25%), Positives = 80/173 (46%), Gaps = 11/173 (6%) Frame = +2 Query: 110 MVPKELITQRLQS----------GAATGRSWQVLLQILQTDGFFGLYAGYAATLLRNLPA 259 + P EL+ RLQ+ A+ W V+ +I + DG G Y G ++TLLR +P Sbjct: 124 LCPTELVKCRLQTMYEMETSGKIAASQNTVWSVVKEIFRKDGPLGFYHGLSSTLLREVPG 183 Query: 260 GVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGA 439 + +E ++F S + L P +L G G P+D +K+R+ + Sbjct: 184 YFFFFGGYELSRSFFASGRSKDELGPVPLMLSGGFGGICLWLAVYPVDCIKSRIQV-LSM 242 Query: 440 QGSRT-VVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMIL 595 G +T +V T ++ EG+ L G+ P ++ + + A+E +R +++ Sbjct: 243 TGKQTGLVRTFLSIVKNEGITALYSGLKPTMIRAFPANGALFLAYEYSRKLMM 295 Score = 36.2 bits (82), Expect = 0.085 Identities = 19/72 (26%), Positives = 37/72 (51%), Gaps = 3/72 (4%) Frame = +2 Query: 116 PKELITQRLQSGAATGRSW---QVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFE 286 P + I R+Q + TG+ + L I++ +G LY+G T++R PA + ++E Sbjct: 229 PVDCIKSRIQVLSMTGKQTGLVRTFLSIVKNEGITALYSGLKPTMIRAFPANGALFLAYE 288 Query: 287 YLKAFALSKSNA 322 Y + +++ A Sbjct: 289 YSRKLMMNQLEA 300
>MFRN2_HUMAN (Q96A46) Mitoferrin-2 (Mitochondrial iron transporter 2) (Solute| carrier family 25 member 28) (Mitochondrial RNA splicing protein 3/4 homolog) (MRS3/4) (hMRS3/4) Length = 364 Score = 65.1 bits (157), Expect = 2e-10 Identities = 47/171 (27%), Positives = 76/171 (44%), Gaps = 8/171 (4%) Frame = +2 Query: 110 MVPKELITQRLQS-GAATGRSWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFE 286 M P E++ QR+Q + R + + Q +G Y Y L N+P + + ++E Sbjct: 188 MNPAEVVKQRMQMYNSPYHRVTDCVRAVWQNEGAGAFYRSYTTQLTMNVPFQAIHFMTYE 247 Query: 287 YLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVG- 463 +L+ + P VL GA AGA++A TTPLDV KT L T+ + + G Sbjct: 248 FLQEHFNPQRR---YNPSSHVLSGACAGAVAAAATTPLDVCKTLLNTQESLALNSHITGH 304 Query: 464 ------TMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMILK 598 + V G+ RG+ RV++ AI + +E + +I K Sbjct: 305 ITGMASAFRTVYQVGGVTAYFRGVQARVIYQIPSTAIAWSVYEFFKYLITK 355 Score = 31.6 bits (70), Expect = 2.1 Identities = 24/77 (31%), Positives = 38/77 (49%), Gaps = 10/77 (12%) Frame = +2 Query: 347 VLCGALAGAISAGLTTPLDVVKTRLMTRV--GAQGSRTVVGTMQEVIAEEGLMGLSRGI- 517 ++ GA+AG + + P+D VKTR+ + A R V+ + +I EGL RG+ Sbjct: 76 MVAGAVAGILEHCVMYPIDCVKTRMQSLQPDPAARYRNVLEALWRIIRTEGLWRPMRGLN 135 Query: 518 ------GP-RVLHSACF 547 GP L+ AC+ Sbjct: 136 VTATGAGPAHALYFACY 152
>MFRN_DROME (Q9VAY3) Mitoferrin| Length = 379 Score = 65.1 bits (157), Expect = 2e-10 Identities = 47/155 (30%), Positives = 78/155 (50%), Gaps = 2/155 (1%) Frame = +2 Query: 116 PKELITQRLQSGAATGRSW-QVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYL 292 P ++I QR+Q + S + I + +GF Y Y L+ NLP + ++++E+ Sbjct: 127 PTDVIKQRMQMYNSPYTSVVSCVRDIYKREGFKAFYRAYGTQLVMNLPYQTIHFTTYEFF 186 Query: 293 KAFALSKSNAPN-LTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTM 469 + +K N P + GA AGA +A +TTPLDV+KT L T+ +R ++ Sbjct: 187 Q----NKMNLERKYNPPVHMAAGAAAGACAAAVTTPLDVIKTLLNTQETGL-TRGMIEAS 241 Query: 470 QEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFE 574 +++ G +G RG RVL+S AI + +E Sbjct: 242 RKIYHMAGPLGFFRGTTARVLYSMPATAICWSTYE 276 Score = 45.8 bits (107), Expect = 1e-04 Identities = 36/158 (22%), Positives = 72/158 (45%), Gaps = 3/158 (1%) Frame = +2 Query: 110 MVPKELITQRLQSGAATGRSWQV---LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSS 280 M P + + R+QS + ++ + L ++ +G G +A +L PA L +++ Sbjct: 32 MYPLDSVKTRMQSLSPPTKNMNIVSTLRTMITREGLLRPIRGASAVVLGAGPAHSLYFAA 91 Query: 281 FEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVV 460 +E K ++ NL V+ GA+A I +++P DV+K R+ S VV Sbjct: 92 YEMTKELTAKFTSVRNLN---YVISGAVATLIHDAISSPTDVIKQRMQMYNSPYTS--VV 146 Query: 461 GTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFE 574 ++++ EG R G +++ + + I + +E Sbjct: 147 SCVRDIYKREGFKAFYRAYGTQLVMNLPYQTIHFTTYE 184 Score = 45.8 bits (107), Expect = 1e-04 Identities = 26/92 (28%), Positives = 47/92 (51%) Frame = +2 Query: 323 PNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMG 502 P + G ++ GA+AG + + PLD VKTR+ + + +V T++ +I EGL+ Sbjct: 10 PTTSVGVNMTAGAIAGVLEHVVMYPLDSVKTRMQSLSPPTKNMNIVSTLRTMITREGLLR 69 Query: 503 LSRGIGPRVLHSACFAAIGYCAFETARLMILK 598 RG VL + ++ + A+E + + K Sbjct: 70 PIRGASAVVLGAGPAHSLYFAAYEMTKELTAK 101
>MFRN1_BRARE (Q287T7) Mitoferrin-1 (Mitochondrial iron transporter 1) (Solute| carrier family 25 member 37) (Protein frascati) Length = 332 Score = 64.7 bits (156), Expect = 2e-10 Identities = 45/164 (27%), Positives = 78/164 (47%), Gaps = 9/164 (5%) Frame = +2 Query: 110 MVPKELITQRLQSGAATGRS-WQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFE 286 M P E++ QR+Q + RS + +L + + +G Y Y+ L N+P + + ++E Sbjct: 149 MNPAEVVKQRMQMYNSPYRSLYDCVLMVSRKEGLAAFYRSYSTQLTMNIPFQAVHFITYE 208 Query: 287 YLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRT---- 454 +++ + P ++ GA AGA+SA +TTPLDV KT L T+ S Sbjct: 209 FMQEHF---NPHRQYRPETHIISGAAAGAVSAAVTTPLDVCKTLLNTQENVALSSAHVSG 265 Query: 455 ----VVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFE 574 +V ++ V G+ +GI RV++ AI + +E Sbjct: 266 HLSGMVNALRTVYRLGGVPAFFKGIQARVIYQMPSTAIAWSVYE 309 Score = 37.7 bits (86), Expect = 0.029 Identities = 23/81 (28%), Positives = 42/81 (51%), Gaps = 2/81 (2%) Frame = +2 Query: 338 GESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGS--RTVVGTMQEVIAEEGLMGLSR 511 G + GA+AG + + P+D VKTR+ + + R+V G ++ ++ EGL+ R Sbjct: 34 GTHMTAGAVAGILEHTVMYPVDSVKTRMQSLQPDPKAQYRSVYGALKRIVRTEGLLRPLR 93 Query: 512 GIGPRVLHSACFAAIGYCAFE 574 G+ VL + A+ + +E Sbjct: 94 GLNITVLGAGPAHALYFACYE 114
>CG69_MOUSE (Q9D8K8) Mitochondrial carrier protein CGI-69 homolog| Length = 359 Score = 64.3 bits (155), Expect = 3e-10 Identities = 46/162 (28%), Positives = 78/162 (48%), Gaps = 9/162 (5%) Frame = +2 Query: 116 PKELITQRLQSGAATGRSWQVLLQILQTDGFF-GLYAGYAATLLRNLPAGVLSYSSFEYL 292 P EL+ +LQ+ + R +Q T G + L+ G+ T LR++P L + ++E + Sbjct: 181 PLELVRTKLQAQHVSYRELASSVQAAVTQGGWRSLWLGWGPTALRDVPFSALYWFNYELV 240 Query: 293 KAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVG--- 463 K++ + G S + G ++G ++A LT P DVVKT+ +GA + V Sbjct: 241 KSWLSGLRPKDQTSVGISFVAGGISGMVAATLTLPFDVVKTQRQMSLGAVEAVRVKPPRV 300 Query: 464 -----TMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFE 574 ++ + AE G GL G PR++ +A AI +E Sbjct: 301 DSTWLLLRRIRAESGTRGLFAGFLPRIIKAAPSCAIMISTYE 342 Score = 56.6 bits (135), Expect = 6e-08 Identities = 39/148 (26%), Positives = 78/148 (52%) Frame = +2 Query: 182 LQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGA 361 ++I++ +G L++G ATL+ +PA + +++++ LKAF +S +L ++ GA Sbjct: 112 VKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGQSLTSDLY--APMVAGA 169 Query: 362 LAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSA 541 LA + + +PL++V+T+L + R + ++Q + + G L G GP L Sbjct: 170 LARMGTVTVVSPLELVRTKLQAQ--HVSYRELASSVQAAVTQGGWRSLWLGWGPTALRDV 227 Query: 542 CFAAIGYCAFETARLMILKSYLESCERK 625 F+A+ + +E ++KS+L K Sbjct: 228 PFSALYWFNYE-----LVKSWLSGLRPK 250 Score = 31.6 bits (70), Expect = 2.1 Identities = 13/45 (28%), Positives = 27/45 (60%) Frame = +2 Query: 167 SWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAF 301 +W +L +I G GL+AG+ +++ P+ + S++E+ K+F Sbjct: 303 TWLLLRRIRAESGTRGLFAGFLPRIIKAAPSCAIMISTYEFGKSF 347
>CMC1_PONPY (Q5RBC8) Calcium-binding mitochondrial carrier protein Aralar1| (Mitochondrial aspartate glutamate carrier 1) (Solute carrier family 25 member 12) Length = 678 Score = 63.9 bits (154), Expect = 4e-10 Identities = 46/146 (31%), Positives = 71/146 (48%), Gaps = 4/146 (2%) Frame = +2 Query: 116 PKELITQRLQ-SGAATGRSWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYL 292 P E++ RLQ +G T L +L+ G FGLY G A LR++P + + + + Sbjct: 446 PLEIVKIRLQVAGEITTGPRVSALNVLRDLGIFGLYKGAKACFLRDIPFSAIYFPVYAHC 505 Query: 293 KAFALSKSNAPNLTPGESVLC-GALAGAISAGLTTPLDVVKTRLM--TRVGAQGSRTVVG 463 K ++ G ++L GA+AG +A L TP DV+KTRL R G V+ Sbjct: 506 KLLLADENGHVG---GLNLLAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVID 562 Query: 464 TMQEVIAEEGLMGLSRGIGPRVLHSA 541 ++++ EEG +G RV S+ Sbjct: 563 CFRKILREEGPSAFWKGTAARVFRSS 588 Score = 52.0 bits (123), Expect = 2e-06 Identities = 45/169 (26%), Positives = 78/169 (46%), Gaps = 10/169 (5%) Frame = +2 Query: 116 PKELITQRLQ----SGAATGR-----SWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVL 268 P +L+ R+Q SG+ G S+ ++L+ +GFFGLY G L+ P + Sbjct: 346 PIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAI 405 Query: 269 SYSSFEYLK-AFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQG 445 + ++++ F + P P E VL G AG T PL++VK RL +V + Sbjct: 406 KLTVNDFVRDKFTRRDGSVP--LPAE-VLAGGCAGGSQVIFTNPLEIVKIRL--QVAGEI 460 Query: 446 SRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMI 592 + + V+ + G+ GL +G L F+AI + + +L++ Sbjct: 461 TTGPRVSALNVLRDLGIFGLYKGAKACFLRDIPFSAIYFPVYAHCKLLL 509 Score = 42.4 bits (98), Expect = 0.001 Identities = 27/76 (35%), Positives = 44/76 (57%), Gaps = 9/76 (11%) Frame = +2 Query: 356 GALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTM---------QEVIAEEGLMGLS 508 G++AGA+ A P+D+VKTR+ + +GS +VVG + ++V+ EG GL Sbjct: 333 GSVAGAVGATAVYPIDLVKTRMQNQ---RGSGSVVGELMYKNSFDCFKKVLRYEGFFGLY 389 Query: 509 RGIGPRVLHSACFAAI 556 RG+ P+++ A AI Sbjct: 390 RGLIPQLIGVAPEKAI 405
>CMC1_HUMAN (O75746) Calcium-binding mitochondrial carrier protein Aralar1| (Mitochondrial aspartate glutamate carrier 1) (Solute carrier family 25 member 12) Length = 678 Score = 63.9 bits (154), Expect = 4e-10 Identities = 46/146 (31%), Positives = 71/146 (48%), Gaps = 4/146 (2%) Frame = +2 Query: 116 PKELITQRLQ-SGAATGRSWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYL 292 P E++ RLQ +G T L +L+ G FGLY G A LR++P + + + + Sbjct: 446 PLEIVKIRLQVAGEITTGPRVSALNVLRDLGIFGLYKGAKACFLRDIPFSAIYFPVYAHC 505 Query: 293 KAFALSKSNAPNLTPGESVLC-GALAGAISAGLTTPLDVVKTRLM--TRVGAQGSRTVVG 463 K ++ G ++L GA+AG +A L TP DV+KTRL R G V+ Sbjct: 506 KLLLADENGHVG---GLNLLAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVID 562 Query: 464 TMQEVIAEEGLMGLSRGIGPRVLHSA 541 ++++ EEG +G RV S+ Sbjct: 563 CFRKILREEGPSAFWKGTAARVFRSS 588 Score = 52.0 bits (123), Expect = 2e-06 Identities = 45/169 (26%), Positives = 78/169 (46%), Gaps = 10/169 (5%) Frame = +2 Query: 116 PKELITQRLQ----SGAATGR-----SWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVL 268 P +L+ R+Q SG+ G S+ ++L+ +GFFGLY G L+ P + Sbjct: 346 PIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAI 405 Query: 269 SYSSFEYLK-AFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQG 445 + ++++ F + P P E VL G AG T PL++VK RL +V + Sbjct: 406 KLTVNDFVRDKFTRRDGSVP--LPAE-VLAGGCAGGSQVIFTNPLEIVKIRL--QVAGEI 460 Query: 446 SRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMI 592 + + V+ + G+ GL +G L F+AI + + +L++ Sbjct: 461 TTGPRVSALNVLRDLGIFGLYKGAKACFLRDIPFSAIYFPVYAHCKLLL 509 Score = 42.4 bits (98), Expect = 0.001 Identities = 27/76 (35%), Positives = 44/76 (57%), Gaps = 9/76 (11%) Frame = +2 Query: 356 GALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTM---------QEVIAEEGLMGLS 508 G++AGA+ A P+D+VKTR+ + +GS +VVG + ++V+ EG GL Sbjct: 333 GSVAGAVGATAVYPIDLVKTRMQNQ---RGSGSVVGELMYKNSFDCFKKVLRYEGFFGLY 389 Query: 509 RGIGPRVLHSACFAAI 556 RG+ P+++ A AI Sbjct: 390 RGLIPQLIGVAPEKAI 405
>ORNT1_HUMAN (Q9Y619) Mitochondrial ornithine transporter 1 (Solute carrier| family 25 member 15) Length = 301 Score = 63.9 bits (154), Expect = 4e-10 Identities = 42/172 (24%), Positives = 76/172 (44%), Gaps = 10/172 (5%) Frame = +2 Query: 110 MVPKELITQRLQS----------GAATGRSWQVLLQILQTDGFFGLYAGYAATLLRNLPA 259 + P EL+ RLQ+ + W V+ IL+ DG G Y G ++TLLR +P Sbjct: 124 LCPTELVKCRLQTMYEMETSGKIAKSQNTVWSVIKSILRKDGPLGFYHGLSSTLLREVPG 183 Query: 260 GVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGA 439 + +E ++F S + L P +L G + G P+D +K+R+ + Sbjct: 184 YFFFFGGYELSRSFFASGRSKDELGPVPLMLSGGVGGICLWLAVYPVDCIKSRIQVLSMS 243 Query: 440 QGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMIL 595 + T V+ EG+ L G+ P ++ + + A+E +R +++ Sbjct: 244 GKQAGFIRTFINVVKNEGITALYSGLKPTMIRAFPANGALFLAYEYSRKLMM 295 Score = 33.1 bits (74), Expect = 0.72 Identities = 16/72 (22%), Positives = 37/72 (51%), Gaps = 3/72 (4%) Frame = +2 Query: 116 PKELITQRLQSGAATGRSW---QVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFE 286 P + I R+Q + +G+ + + +++ +G LY+G T++R PA + ++E Sbjct: 229 PVDCIKSRIQVLSMSGKQAGFIRTFINVVKNEGITALYSGLKPTMIRAFPANGALFLAYE 288 Query: 287 YLKAFALSKSNA 322 Y + +++ A Sbjct: 289 YSRKLMMNQLEA 300
>GHC2_MOUSE (Q9DB41) Mitochondrial glutamate carrier 2 (GC-2) (Glutamate/H(+)| symporter 2) (Solute carrier family 25 member 18) (Fragment) Length = 312 Score = 63.5 bits (153), Expect = 5e-10 Identities = 39/119 (32%), Positives = 61/119 (51%), Gaps = 3/119 (2%) Frame = +2 Query: 185 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGAL 364 ++L+T G GLY G ATLLR++P ++ + F L +S+ + S + G Sbjct: 169 ELLRTQGLSGLYRGLGATLLRDIPFSIIYFPLFANLNQLGVSELTG-KASFTHSFVAGCT 227 Query: 365 AGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGT---MQEVIAEEGLMGLSRGIGPRVL 532 AG+++A TPLDV+KTR+ T G T G +++ +EG +G G R L Sbjct: 228 AGSVAAVAVTPLDVLKTRIQTLKKGLGEDTYSGVTDCARKLWTQEGPAAFMKGAGCRAL 286 Score = 43.9 bits (102), Expect = 4e-04 Identities = 36/155 (23%), Positives = 64/155 (41%), Gaps = 24/155 (15%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 358 L++ + +GF G+Y G A L P + ++ ++L+ + NL +L G Sbjct: 49 LMKTARAEGFLGMYRGAAVNLTLVTPEKAIKLAANDFLRQLLMQDGTQRNLK--MEMLAG 106 Query: 359 ALAGAISAGLTTPLDVVKTRLM----TRVGAQGSRTVVGT-------------------- 466 AG +T P++++K +L V Q S + T Sbjct: 107 CGAGICQVVITCPMEMLKIQLQDAGRLAVCHQASASATPTSRPYSTGSTSTHRRPSATLI 166 Query: 467 MQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAF 571 +E++ +GL GL RG+G +L F+ I + F Sbjct: 167 ARELLRTQGLSGLYRGLGATLLRDIPFSIIYFPLF 201 Score = 36.6 bits (83), Expect = 0.065 Identities = 16/56 (28%), Positives = 28/56 (50%) Frame = +2 Query: 347 VLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRG 514 ++ G +AG + P+D+ KTRL + G R + + + EG +G+ RG Sbjct: 9 IINGGIAGLVGVTCVFPIDLAKTRLQNQQGKDVYRGMTDCLMKTARAEGFLGMYRG 64
>UCP5_MOUSE (Q9Z2B2) Brain mitochondrial carrier protein 1 (BMCP-1)| (Mitochondrial uncoupling protein 5) (UCP 5) (Solute carrier family 25 member 14) Length = 325 Score = 62.8 bits (151), Expect = 8e-10 Identities = 35/144 (24%), Positives = 71/144 (49%) Frame = +2 Query: 170 WQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESV 349 + L +I + +G LY+G A LLR G + ++ LK + + L ++ Sbjct: 88 FHALFRIYKEEGILALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLI--NM 145 Query: 350 LCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRV 529 +CG ++G IS+ + P DV+K R+ + G+ +++G+ ++ +EG GL RG+ P Sbjct: 146 ICGVVSGVISSTIANPTDVLKIRMQAQ-GSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTA 204 Query: 530 LHSACFAAIGYCAFETARLMILKS 601 +A + ++ + ++ S Sbjct: 205 QRAAIVVGVELPVYDITKKHLIVS 228 Score = 34.3 bits (77), Expect = 0.32 Identities = 22/88 (25%), Positives = 40/88 (45%), Gaps = 7/88 (7%) Frame = +2 Query: 356 GALAGAISAGLTTPLDVVKTRLM-------TRVGAQGSRTVVGTMQEVIAEEGLMGLSRG 514 G LA ++ T P+D+ KTRL R R + + + EEG++ L G Sbjct: 47 GGLASIVAEFGTFPVDLTKTRLQVQGQSIDVRFKEIKYRGMFHALFRIYKEEGILALYSG 106 Query: 515 IGPRVLHSACFAAIGYCAFETARLMILK 598 I P +L A + I +++ + + ++ Sbjct: 107 IAPALLRQASYGTIKIGIYQSLKRLFVE 134 Score = 33.5 bits (75), Expect = 0.55 Identities = 37/161 (22%), Positives = 68/161 (42%), Gaps = 8/161 (4%) Frame = +2 Query: 116 PKELITQRLQSGAATGRSWQV--LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEY 289 P +++ R+Q+ + + + + I Q +G GL+ G T R + ++ Sbjct: 161 PTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDI 220 Query: 290 LKAFALSKSNAPN--LTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVV- 460 K + + LT S LAGA+++ P+DVV+TR+M + G + Sbjct: 221 TKKHLIVSGMLGDTILTHFVSSFTCGLAGALASN---PVDVVRTRMMNQRAIVGHVDLYK 277 Query: 461 GTMQEVI---AEEGLMGLSRGIGPRVLHSACFAAIGYCAFE 574 GT+ ++ EG L +G P L + I + +E Sbjct: 278 GTLDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYE 318 Score = 29.6 bits (65), Expect = 8.0 Identities = 13/39 (33%), Positives = 24/39 (61%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLK 295 +L++ + +GFF LY G+ LR P ++ + ++E LK Sbjct: 283 ILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLK 321
>COLT_DROME (Q9VQG4) Congested-like trachea protein| Length = 306 Score = 62.8 bits (151), Expect = 8e-10 Identities = 45/160 (28%), Positives = 78/160 (48%), Gaps = 11/160 (6%) Frame = +2 Query: 110 MVPKELITQRLQSGAATG--RSWQVLL----QILQTDGFFGLYAGYAATLLRNLPAGVLS 271 M P E I LQ+ G R + ++ ++ + G ++ G AT+LR+LPA L Sbjct: 133 MAPGERIKVLLQTQQGQGGERKYNGMIDCAGKLYKEGGLRSVFKGSCATMLRDLPANGLY 192 Query: 272 YSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSR 451 + +E L+ A SKS ++ ++ G +AG L P DV+K+RL + Sbjct: 193 FLVYEALQDVAKSKSETGQISTASTIFAGGVAGMAYWILGMPADVLKSRLQSAPEGTYKH 252 Query: 452 TVVGTMQEVIAEEGLMGLSRGIGPRVL-----HSACFAAI 556 + +++I ++G + L RG+ P +L ++ACF I Sbjct: 253 GIRSVFKDLIVKDGPLALYRGVTPIMLRAFPANAACFFGI 292
>UCP5_HUMAN (O95258) Brain mitochondrial carrier protein 1 (BMCP-1)| (Mitochondrial uncoupling protein 5) (UCP 5) (Solute carrier family 25 member 14) Length = 325 Score = 62.4 bits (150), Expect = 1e-09 Identities = 35/144 (24%), Positives = 71/144 (49%) Frame = +2 Query: 170 WQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESV 349 + L +I + +G LY+G A LLR G + ++ LK + + L ++ Sbjct: 88 FHALFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLI--NM 145 Query: 350 LCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRV 529 +CG ++G IS+ + P DV+K R+ + G+ +++G+ ++ +EG GL RG+ P Sbjct: 146 ICGVVSGVISSTIANPTDVLKIRMQAQ-GSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTA 204 Query: 530 LHSACFAAIGYCAFETARLMILKS 601 +A + ++ + ++ S Sbjct: 205 QRAAIVVGVELPVYDITKKHLILS 228 Score = 33.9 bits (76), Expect = 0.42 Identities = 22/88 (25%), Positives = 40/88 (45%), Gaps = 7/88 (7%) Frame = +2 Query: 356 GALAGAISAGLTTPLDVVKTRLM-------TRVGAQGSRTVVGTMQEVIAEEGLMGLSRG 514 G LA ++ T P+D+ KTRL R R + + + EEG++ L G Sbjct: 47 GGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSG 106 Query: 515 IGPRVLHSACFAAIGYCAFETARLMILK 598 I P +L A + I +++ + + ++ Sbjct: 107 IAPALLRQASYGTIKIGIYQSLKRLFVE 134 Score = 33.1 bits (74), Expect = 0.72 Identities = 37/161 (22%), Positives = 68/161 (42%), Gaps = 8/161 (4%) Frame = +2 Query: 116 PKELITQRLQSGAATGRSWQV--LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEY 289 P +++ R+Q+ + + + + I Q +G GL+ G T R + ++ Sbjct: 161 PTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDI 220 Query: 290 LKAFALSKSNAPN--LTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVV- 460 K + + LT S LAGA+++ P+DVV+TR+M + G + Sbjct: 221 TKKHLILSGMMGDTILTHFVSSFTCGLAGALASN---PVDVVRTRMMNQRAIVGHVDLYK 277 Query: 461 GTMQEVI---AEEGLMGLSRGIGPRVLHSACFAAIGYCAFE 574 GT+ ++ EG L +G P L + I + +E Sbjct: 278 GTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYE 318 Score = 29.6 bits (65), Expect = 8.0 Identities = 13/39 (33%), Positives = 24/39 (61%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLK 295 +L++ + +GFF LY G+ LR P ++ + ++E LK Sbjct: 283 ILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLK 321
>AGC1_ASHGO (Q75AH6) Mitochondrial aspartate-glutamate transporter AGC1| (Aspartate-glutamate carrier 1) Length = 911 Score = 62.4 bits (150), Expect = 1e-09 Identities = 51/170 (30%), Positives = 76/170 (44%), Gaps = 17/170 (10%) Frame = +2 Query: 116 PKELITQRLQSG----AATGRSWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSF 283 P E++ RLQ A R+ + +++ G GLY G A LLR++P + Sbjct: 637 PLEIVKIRLQVKSDYVADAARNSVNAISVIKNLGLIGLYRGAGACLLRDIPFSAI----- 691 Query: 284 EYLKAFALSKSNAPNLTPGES-----------VLCGALAGAISAGLTTPLDVVKTRLM-- 424 Y +A KSN N P +S ++ G LAG +A LTTP DV+KTRL Sbjct: 692 -YFPTYAHIKSNVFNFDPKDSDKRNKLNTWQLLVSGGLAGMPAAFLTTPFDVIKTRLQID 750 Query: 425 TRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFE 574 + G + + ++ EEG+ +G RVL S+ A+E Sbjct: 751 PKKGESVYNGIWDAARTILKEEGIKSFFKGGPARVLRSSPQFGFTLAAYE 800 Score = 58.5 bits (140), Expect = 2e-08 Identities = 47/152 (30%), Positives = 75/152 (49%), Gaps = 5/152 (3%) Frame = +2 Query: 116 PKELITQRLQSGAATGR---SWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFE 286 P +++ R+Q+ + S LL+IL +G GLY+G L+ P + + + Sbjct: 543 PIDMVKTRMQAQRDFSKYKNSIDCLLKILSKEGVRGLYSGLGPQLIGVAPEKAIKLTVND 602 Query: 287 YLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVG--AQGSRTVV 460 +++A + +L P E ++ GA AGA T PL++VK RL + A +R V Sbjct: 603 HMRATLAGRDGKLSL-PCE-IISGATAGACQVVFTNPLEIVKIRLQVKSDYVADAARNSV 660 Query: 461 GTMQEVIAEEGLMGLSRGIGPRVLHSACFAAI 556 + VI GL+GL RG G +L F+AI Sbjct: 661 NAI-SVIKNLGLIGLYRGAGACLLRDIPFSAI 691 Score = 44.3 bits (103), Expect = 3e-04 Identities = 21/67 (31%), Positives = 41/67 (61%) Frame = +2 Query: 356 GALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLH 535 G++AG I A + P+D+VKTR+ + + + + +++++EG+ GL G+GP+++ Sbjct: 530 GSVAGCIGAMVVYPIDMVKTRMQAQRDFSKYKNSIDCLLKILSKEGVRGLYSGLGPQLIG 589 Query: 536 SACFAAI 556 A AI Sbjct: 590 VAPEKAI 596
>CG69_HUMAN (Q9BZJ4) Mitochondrial carrier protein CGI-69| Length = 359 Score = 62.0 bits (149), Expect = 1e-09 Identities = 44/162 (27%), Positives = 78/162 (48%), Gaps = 9/162 (5%) Frame = +2 Query: 116 PKELITQRLQSGAATGRSWQVLLQI-LQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYL 292 P EL+ +LQ+ + R ++ + G+ L+ G+ T LR++P L + ++E + Sbjct: 181 PLELMRTKLQAQHVSYRELGACVRTAVAQGGWRSLWLGWGPTALRDVPFSALYWFNYELV 240 Query: 293 KAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVG--- 463 K++ + G S + G ++G ++A LT P DVVKT+ +GA + V Sbjct: 241 KSWLNGLRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRVNPLHV 300 Query: 464 -----TMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFE 574 ++ + AE G GL G PR++ +A AI +E Sbjct: 301 DSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYE 342 Score = 52.4 bits (124), Expect = 1e-06 Identities = 37/148 (25%), Positives = 78/148 (52%) Frame = +2 Query: 182 LQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGA 361 ++I++ +G L++G ATL+ +PA + +++++ LKAF ++ +L ++ GA Sbjct: 112 VKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLY--APMVAGA 169 Query: 362 LAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSA 541 LA + + +PL++++T+L + R + ++ +A+ G L G GP L Sbjct: 170 LARLGTVTVISPLELMRTKLQAQ--HVSYRELGACVRTAVAQGGWRSLWLGWGPTALRDV 227 Query: 542 CFAAIGYCAFETARLMILKSYLESCERK 625 F+A+ + +E ++KS+L K Sbjct: 228 PFSALYWFNYE-----LVKSWLNGLRPK 250 Score = 31.6 bits (70), Expect = 2.1 Identities = 13/45 (28%), Positives = 27/45 (60%) Frame = +2 Query: 167 SWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAF 301 +W +L +I G GL+AG+ +++ P+ + S++E+ K+F Sbjct: 303 TWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYEFGKSF 347
>GHC2_HUMAN (Q9H1K4) Mitochondrial glutamate carrier 2 (GC-2) (Glutamate/H(+)| symporter 2) (Solute carrier family 25 member 18) Length = 315 Score = 60.8 bits (146), Expect = 3e-09 Identities = 38/119 (31%), Positives = 62/119 (52%), Gaps = 3/119 (2%) Frame = +2 Query: 185 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGAL 364 ++L+T G GLY G ATLLR++P ++ + F L ++ A + S + G + Sbjct: 172 ELLRTQGLAGLYRGLGATLLRDIPFSIIYFPLFANLNNLGFNEL-AGKASFAHSFVSGCV 230 Query: 365 AGAISAGLTTPLDVVKTRLMT---RVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVL 532 AG+I+A TPLDV+KTR+ T +G + +++ +EG +G G R L Sbjct: 231 AGSIAAVAVTPLDVLKTRIQTLKKGLGEDMYSGITDCARKLWIQEGPSAFMKGAGCRAL 289 Score = 47.0 bits (110), Expect = 5e-05 Identities = 44/179 (24%), Positives = 75/179 (41%), Gaps = 27/179 (15%) Frame = +2 Query: 116 PKELITQRLQS--GAATGRSW-QVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFE 286 P +L RLQ+ G A + L++ + +GFFG+Y G A L P + ++ + Sbjct: 28 PIDLAKTRLQNQHGKAMYKGMIDCLMKTARAEGFFGMYRGAAVNLTLVTPEKAIKLAAND 87 Query: 287 YLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLM----TRVGAQGSRT 454 + + + NL +L G AG +T P++++K +L V QGS + Sbjct: 88 FFRRLLMEDGMQRNLK--MEMLAGCGAGMCQVVVTCPMEMLKIQLQDAGRLAVHHQGSAS 145 Query: 455 VVGTMQ--------------------EVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAF 571 T + E++ +GL GL RG+G +L F+ I + F Sbjct: 146 APSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAGLYRGLGATLLRDIPFSIIYFPLF 204 Score = 33.9 bits (76), Expect = 0.42 Identities = 15/53 (28%), Positives = 26/53 (49%) Frame = +2 Query: 356 GALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRG 514 G +AG + P+D+ KTRL + G + ++ + + EG G+ RG Sbjct: 15 GGVAGLVGVTCVFPIDLAKTRLQNQHGKAMYKGMIDCLMKTARAEGFFGMYRG 67
>MCAT_HUMAN (O43772) Mitochondrial carnitine/acylcarnitine carrier protein| (Carnitine/acylcarnitine translocase) (CAC) (Solute carrier family 25 member 20) Length = 301 Score = 60.1 bits (144), Expect = 6e-09 Identities = 43/163 (26%), Positives = 75/163 (46%), Gaps = 6/163 (3%) Frame = +2 Query: 110 MVPKELITQRLQSGAATGRS-----WQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSY 274 M P E I LQ A++G S ++ Q G G+Y G TL+R++PA + + Sbjct: 128 MTPGERIKCLLQIQASSGESKYTGTLDCAKKLYQEFGIRGIYKGTVLTLMRDVPASGMYF 187 Query: 275 SSFEYLK-AFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSR 451 ++E+LK F L+ ++ G +AG + + P DV+K+R T + Sbjct: 188 MTYEWLKNIFTPEGKRVSELSAPRILVAGGIAGIFNWAVAIPPDVLKSRFQTAPPGKYPN 247 Query: 452 TVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETA 580 ++E+I +EG+ L +G ++ + A + FE A Sbjct: 248 GFRDVLRELIRDEGVTSLYKGFNAVMIRAFPANAACFLGFEVA 290
>YQ51_CAEEL (Q09461) Putative mitochondrial carrier C16C10.1| Length = 360 Score = 60.1 bits (144), Expect = 6e-09 Identities = 41/168 (24%), Positives = 82/168 (48%), Gaps = 5/168 (2%) Frame = +2 Query: 116 PKELITQRLQSGAATGRSWQVLLQI-LQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYL 292 P E+I ++QS T L++ + T G Y G+ T+LR++P + ++ ++ Sbjct: 194 PIEMIRTKMQSKRLTYHEIGHLVRSSMATKGISSFYLGWTPTMLRDIPFSGIYWAGYDLF 253 Query: 293 KAFALSKSNAPNLTPGE-SVLCGALAGAISAGLTTPLDVVKTRLMTRVGA---QGSRTVV 460 K L + P+ P S + GA AG +++ T P DV+KT R+G ++++ Sbjct: 254 KT-NLQRRQGPDHNPFVVSFVSGAAAGVVASIFTHPFDVIKTNCQIRIGGSIDDMNKSIT 312 Query: 461 GTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMILKSY 604 ++++ G+ S G+ PR++ + AI +E + + K++ Sbjct: 313 TVIKDMYHSRGISAFSSGLVPRLVKVSPSCAIMISFYEYFKFLFQKNH 360
>UCP2_RAT (P56500) Mitochondrial uncoupling protein 2 (UCP 2)| Length = 309 Score = 59.3 bits (142), Expect = 9e-09 Identities = 39/146 (26%), Positives = 67/146 (45%), Gaps = 3/146 (2%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 358 +L +++T+G LY G A L R + + ++ +K F S + G +L G Sbjct: 66 ILTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSEHAGI--GSRLLAG 123 Query: 359 ALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQ---EVIAEEGLMGLSRGIGPRV 529 + GA++ + P DVVK R + A G R T++ + EEG+ GL +G P V Sbjct: 124 STTGALAVAVAQPTDVVKVRFQAQARAGGGRRYQSTVEAYKTIAREEGIRGLWKGTSPNV 183 Query: 530 LHSACFAAIGYCAFETARLMILKSYL 607 +A ++ + +LK+ L Sbjct: 184 ARNAIVNCTELVTYDLIKDTLLKANL 209 Score = 37.7 bits (86), Expect = 0.029 Identities = 37/170 (21%), Positives = 71/170 (41%), Gaps = 7/170 (4%) Frame = +2 Query: 116 PKELITQRLQSGAATG--RSWQVLLQILQT----DGFFGLYAGYAATLLRNLPAGVLSYS 277 P +++ R Q+ A G R +Q ++ +T +G GL+ G + + RN Sbjct: 136 PTDVVKVRFQAQARAGGGRRYQSTVEAYKTIAREEGIRGLWKGTSPNVARNAIVNCTELV 195 Query: 278 SFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTV 457 +++ +K L + + P AG + + +P+DVVKTR M A G Sbjct: 196 TYDLIKDTLLKANLMTDDLPCHFTSAFG-AGFCTTVIASPVDVVKTRYMN--SALGQYHS 252 Query: 458 VG-TMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMILKSY 604 G ++ +EG +G P L + + + +E + ++ +Y Sbjct: 253 AGHCALTMLRKEGPRAFYKGFMPSFLRLGSWNVVMFVTYEQLKRALMAAY 302 Score = 30.4 bits (67), Expect = 4.7 Identities = 22/87 (25%), Positives = 38/87 (43%), Gaps = 9/87 (10%) Frame = +2 Query: 365 AGAISAGLTTPLDVVKTRLMTRVGAQG---------SRTVVGTMQEVIAEEGLMGLSRGI 517 A I+ +T PLD K RL + +QG R V+GT+ ++ EG L G+ Sbjct: 23 AACIADLITFPLDTAKVRLQIQGESQGLARTAASAQYRGVLGTILTMVRTEGPRSLYNGL 82 Query: 518 GPRVLHSACFAAIGYCAFETARLMILK 598 + FA++ +++ + K Sbjct: 83 VAGLQRQMSFASVRIGLYDSVKQFYTK 109
>UCP2_MOUSE (P70406) Mitochondrial uncoupling protein 2 (UCP 2) (UCPH)| Length = 309 Score = 59.3 bits (142), Expect = 9e-09 Identities = 39/146 (26%), Positives = 67/146 (45%), Gaps = 3/146 (2%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 358 +L +++T+G LY G A L R + + ++ +K F S + G +L G Sbjct: 66 ILTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSEHAGI--GSRLLAG 123 Query: 359 ALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQ---EVIAEEGLMGLSRGIGPRV 529 + GA++ + P DVVK R + A G R T++ + EEG+ GL +G P V Sbjct: 124 STTGALAVAVAQPTDVVKVRFQAQARAGGGRRYQSTVEAYKTIAREEGIRGLWKGTSPNV 183 Query: 530 LHSACFAAIGYCAFETARLMILKSYL 607 +A ++ + +LK+ L Sbjct: 184 ARNAIVNCAELVTYDLIKDTLLKANL 209 Score = 37.7 bits (86), Expect = 0.029 Identities = 37/170 (21%), Positives = 71/170 (41%), Gaps = 7/170 (4%) Frame = +2 Query: 116 PKELITQRLQSGAATG--RSWQVLLQILQT----DGFFGLYAGYAATLLRNLPAGVLSYS 277 P +++ R Q+ A G R +Q ++ +T +G GL+ G + + RN Sbjct: 136 PTDVVKVRFQAQARAGGGRRYQSTVEAYKTIAREEGIRGLWKGTSPNVARNAIVNCAELV 195 Query: 278 SFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTV 457 +++ +K L + + P AG + + +P+DVVKTR M A G Sbjct: 196 TYDLIKDTLLKANLMTDDLPCHFTSAFG-AGFCTTVIASPVDVVKTRYMN--SALGQYHS 252 Query: 458 VG-TMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMILKSY 604 G ++ +EG +G P L + + + +E + ++ +Y Sbjct: 253 AGHCALTMLRKEGPRAFYKGFMPSFLRLGSWNVVMFVTYEQLKRALMAAY 302 Score = 30.4 bits (67), Expect = 4.7 Identities = 22/87 (25%), Positives = 38/87 (43%), Gaps = 9/87 (10%) Frame = +2 Query: 365 AGAISAGLTTPLDVVKTRLMTRVGAQG---------SRTVVGTMQEVIAEEGLMGLSRGI 517 A I+ +T PLD K RL + +QG R V+GT+ ++ EG L G+ Sbjct: 23 AACIADLITFPLDTAKVRLQIQGESQGLVRTAASAQYRGVLGTILTMVRTEGPRSLYNGL 82 Query: 518 GPRVLHSACFAAIGYCAFETARLMILK 598 + FA++ +++ + K Sbjct: 83 VAGLQRQMSFASVRIGLYDSVKQFYTK 109
>UCP2_HUMAN (P55851) Mitochondrial uncoupling protein 2 (UCP 2) (UCPH)| Length = 309 Score = 59.3 bits (142), Expect = 9e-09 Identities = 39/146 (26%), Positives = 67/146 (45%), Gaps = 3/146 (2%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 358 +L +++T+G LY G A L R + + ++ +K F S ++ G +L G Sbjct: 66 ILTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSEHASI--GSRLLAG 123 Query: 359 ALAGAISAGLTTPLDVVKTRLMTRVGAQGSR---TVVGTMQEVIAEEGLMGLSRGIGPRV 529 + GA++ + P DVVK R + A G R + V + + EEG GL +G P V Sbjct: 124 STTGALAVAVAQPTDVVKVRFQAQARAGGGRRYQSTVNAYKTIAREEGFRGLWKGTSPNV 183 Query: 530 LHSACFAAIGYCAFETARLMILKSYL 607 +A ++ + +LK+ L Sbjct: 184 ARNAIVNCAELVTYDLIKDALLKANL 209 Score = 38.5 bits (88), Expect = 0.017 Identities = 39/167 (23%), Positives = 71/167 (42%), Gaps = 7/167 (4%) Frame = +2 Query: 116 PKELITQRLQSGAATG--RSWQVLLQILQT----DGFFGLYAGYAATLLRNLPAGVLSYS 277 P +++ R Q+ A G R +Q + +T +GF GL+ G + + RN Sbjct: 136 PTDVVKVRFQAQARAGGGRRYQSTVNAYKTIAREEGFRGLWKGTSPNVARNAIVNCAELV 195 Query: 278 SFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTV 457 +++ +K AL K+N AG + + +P+DVVKTR M A G + Sbjct: 196 TYDLIKD-ALLKANLMTDDLPCHFTSAFGAGFCTTVIASPVDVVKTRYMN--SALGQYSS 252 Query: 458 VG-TMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMIL 595 G ++ +EG +G P L + + + +E + ++ Sbjct: 253 AGHCALTMLQKEGPRAFYKGFMPSFLRLGSWNVVMFVTYEQLKRALM 299 Score = 30.8 bits (68), Expect = 3.6 Identities = 22/87 (25%), Positives = 38/87 (43%), Gaps = 9/87 (10%) Frame = +2 Query: 365 AGAISAGLTTPLDVVKTRLMTRVGAQGS---------RTVVGTMQEVIAEEGLMGLSRGI 517 A I+ +T PLD K RL + +QG R V+GT+ ++ EG L G+ Sbjct: 23 AACIADLITFPLDTAKVRLQIQGESQGPVRATASAQYRGVMGTILTMVRTEGPRSLYNGL 82 Query: 518 GPRVLHSACFAAIGYCAFETARLMILK 598 + FA++ +++ + K Sbjct: 83 VAGLQRQMSFASVRIGLYDSVKQFYTK 109
>MCAT_MOUSE (Q9Z2Z6) Mitochondrial carnitine/acylcarnitine carrier protein| (Carnitine/acylcarnitine translocase) (CAC) (mCAC) (Solute carrier family 25 member 20) Length = 301 Score = 58.5 bits (140), Expect = 2e-08 Identities = 43/163 (26%), Positives = 75/163 (46%), Gaps = 6/163 (3%) Frame = +2 Query: 110 MVPKELITQRLQSGAATGRS-----WQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSY 274 M P E I LQ A++G + ++ Q G G Y G TL+R++PA + + Sbjct: 128 MTPGERIKCLLQIQASSGENKYSGTLDCAKKLYQEFGIRGFYKGTVLTLMRDVPASGMYF 187 Query: 275 SSFEYLK-AFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSR 451 ++E+LK F + +L+ ++ G AG + + P DV+K+R T + Sbjct: 188 MTYEWLKNLFTPEGKSVSDLSVPRILVAGGFAGIFNWAVAIPPDVLKSRFQTAPPGKYPN 247 Query: 452 TVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETA 580 ++E+I EEG+ L +G ++ + A + FE A Sbjct: 248 GFRDVLRELIREEGVTSLYKGFNAVMIRAFPANAACFLGFEIA 290 Score = 35.8 bits (81), Expect = 0.11 Identities = 25/87 (28%), Positives = 42/87 (48%), Gaps = 10/87 (11%) Frame = +2 Query: 329 LTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVV--GTM---QEVIAEEG 493 ++P +++L G G + PLD VK RL T+ + + + GT+ ++ + EG Sbjct: 8 ISPFKNLLAGGFGGMCLVFVGHPLDTVKVRLQTQPPSLSGQPPMYSGTLDCFRKTLMREG 67 Query: 494 LMGLSRG-----IGPRVLHSACFAAIG 559 + GL RG IG + + CF G Sbjct: 68 ITGLYRGMAAPIIGVTPMFAVCFFGFG 94
>UCP3_MOUSE (P56501) Mitochondrial uncoupling protein 3 (UCP 3)| Length = 308 Score = 57.8 bits (138), Expect = 3e-08 Identities = 41/148 (27%), Positives = 70/148 (47%), Gaps = 5/148 (3%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 358 +L +++T+G Y+G A L R + + ++ +K F K A + + +L G Sbjct: 62 ILTMVRTEGPRSPYSGLVAGLHRQMSFASIRIGLYDSVKQFYTPKG-ADHSSVAIRILAG 120 Query: 359 ALAGAISAGLTTPLDVVKTRL--MTRVGAQGSRTVVGTM---QEVIAEEGLMGLSRGIGP 523 GA++ P DVVK R M R+G G R GTM + + EEG+ GL +G P Sbjct: 121 CTTGAMAVTCAQPTDVVKVRFQAMIRLGTGGERKYRGTMDAYRTIAREEGVRGLWKGTWP 180 Query: 524 RVLHSACFAAIGYCAFETARLMILKSYL 607 + +A ++ + +L+S+L Sbjct: 181 NITRNAIVNCAEMVTYDIIKEKLLESHL 208 Score = 37.0 bits (84), Expect = 0.050 Identities = 31/137 (22%), Positives = 59/137 (43%) Frame = +2 Query: 188 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 367 I + +G GL+ G + RN +++ +K L + P V A Sbjct: 165 IAREEGVRGLWKGTWPNITRNAIVNCAEMVTYDIIKEKLLESHLFTDNFPCHFVSAFG-A 223 Query: 368 GAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACF 547 G + + +P+DVVKTR M + R+ + M +++A+EG +G P L + Sbjct: 224 GFCATVVASPVDVVKTRYMNAPLGR-YRSPLHCMLKMVAQEGPTAFYKGFVPSFLRLGAW 282 Query: 548 AAIGYCAFETARLMILK 598 + + +E + ++K Sbjct: 283 NVMMFVTYEQLKRALMK 299
>MCAT_MACFA (Q8HXY2) Mitochondrial carnitine/acylcarnitine carrier protein| (Carnitine/acylcarnitine translocase) (CAC) (Solute carrier family 25 member 20) Length = 301 Score = 57.8 bits (138), Expect = 3e-08 Identities = 41/163 (25%), Positives = 75/163 (46%), Gaps = 6/163 (3%) Frame = +2 Query: 110 MVPKELITQRLQSGAATGRS-----WQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSY 274 M P E I LQ A++G + ++ Q G G+Y G TL+R++PA + + Sbjct: 128 MTPGERIKCLLQIQASSGETKYTGTLDCAKKLYQEFGIRGIYKGTVVTLMRDVPASGMYF 187 Query: 275 SSFEYLK-AFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSR 451 ++E++K F L+ ++ G +AG + + P DV+K+R T + Sbjct: 188 MTYEWVKNIFTPEGKRVSELSVPRVLVAGGIAGIFNWAVAIPPDVLKSRFQTAPPGKYPN 247 Query: 452 TVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETA 580 ++E+I +EG+ L +G ++ + A + FE A Sbjct: 248 GFRDVLRELIPDEGVTSLYKGFNAVMIRAFPANAACFLGFEVA 290
>UCP2_CYPCA (Q9W725) Mitochondrial uncoupling protein 2 (UCP 2)| Length = 310 Score = 57.8 bits (138), Expect = 3e-08 Identities = 38/143 (26%), Positives = 65/143 (45%), Gaps = 3/143 (2%) Frame = +2 Query: 188 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 367 +++ +G LY+G A L R + + ++ +K F S + G ++ G Sbjct: 70 MVRVEGPRSLYSGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSEHVGI--GSRLMAGCTT 127 Query: 368 GAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTM---QEVIAEEGLMGLSRGIGPRVLHS 538 GA++ L P DVVK R + A ++ GTM + + EEG GL +G GP + + Sbjct: 128 GAMAVALAQPTDVVKVRFQAQNSAGANKRYHGTMDAYRTIAKEEGFRGLWKGTGPNITRN 187 Query: 539 ACFAAIGYCAFETARLMILKSYL 607 A ++ + +LKS L Sbjct: 188 AIVNCTELVTYDLIKDALLKSSL 210 Score = 37.0 bits (84), Expect = 0.050 Identities = 33/159 (20%), Positives = 62/159 (38%), Gaps = 6/159 (3%) Frame = +2 Query: 116 PKELITQRLQSGAATGRS------WQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYS 277 P +++ R Q+ + G + I + +GF GL+ G + RN Sbjct: 137 PTDVVKVRFQAQNSAGANKRYHGTMDAYRTIAKEEGFRGLWKGTGPNITRNAIVNCTELV 196 Query: 278 SFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTV 457 +++ +K L S + P AG + + +P+DVVKTR M Q + Sbjct: 197 TYDLIKDALLKSSLMTDDLPCHFTSAFG-AGFCTTVIASPVDVVKTRYMNSAPGQYC-SA 254 Query: 458 VGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFE 574 + ++ +EG +G P L + + + +E Sbjct: 255 LNCAVAMLTKEGPKAFYKGFMPSFLRLGSWNVVMFVTYE 293
>UCP2_BRARE (Q9W720) Mitochondrial uncoupling protein 2 (UCP 2)| Length = 310 Score = 57.8 bits (138), Expect = 3e-08 Identities = 37/143 (25%), Positives = 66/143 (46%), Gaps = 3/143 (2%) Frame = +2 Query: 188 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 367 +++ +G LY+G A L R + + ++ +K F S+ + G ++ G Sbjct: 70 MVRVEGPRSLYSGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSDHAGI--GSRLMAGCTT 127 Query: 368 GAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTM---QEVIAEEGLMGLSRGIGPRVLHS 538 GA++ + P DV+K R +V A S+ TM + + EEG GL +G GP + + Sbjct: 128 GAMAVAVAQPTDVLKVRFQAQVSAGASKRYHSTMDAYRTIAKEEGFRGLWKGTGPNITRN 187 Query: 539 ACFAAIGYCAFETARLMILKSYL 607 A ++ + +LKS L Sbjct: 188 AIVNCTELVTYDLIKDALLKSSL 210 Score = 38.5 bits (88), Expect = 0.017 Identities = 34/159 (21%), Positives = 63/159 (39%), Gaps = 6/159 (3%) Frame = +2 Query: 116 PKELITQRLQSGAATGRS------WQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYS 277 P +++ R Q+ + G S I + +GF GL+ G + RN Sbjct: 137 PTDVLKVRFQAQVSAGASKRYHSTMDAYRTIAKEEGFRGLWKGTGPNITRNAIVNCTELV 196 Query: 278 SFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTV 457 +++ +K L S + P AG + + +P+DVVKTR M Q S + Sbjct: 197 TYDLIKDALLKSSLMTDDLPCHFTSAFG-AGFCTTIIASPVDVVKTRYMNSAQGQYS-SA 254 Query: 458 VGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFE 574 + ++ ++G +G P L + + + +E Sbjct: 255 LNCAVAMLTKKGPKAFFKGFMPSFLRLGSWNVVMFVTYE 293
>UCP2_PIG (O97562) Mitochondrial uncoupling protein 2 (UCP 2)| Length = 309 Score = 57.4 bits (137), Expect = 4e-08 Identities = 39/146 (26%), Positives = 66/146 (45%), Gaps = 3/146 (2%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 358 +L +++ +G LY G A L R + + ++ +K F S + G +L G Sbjct: 66 ILTMVRNEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKHFYTKGSEHAGI--GSRLLAG 123 Query: 359 ALAGAISAGLTTPLDVVKTRLMTRVGAQGS---RTVVGTMQEVIAEEGLMGLSRGIGPRV 529 + GA++ + P DVVK R + A G R+ V + + EEGL GL +G P V Sbjct: 124 STTGALAVAVAQPTDVVKVRFQAQARAGGGRRYRSTVDAYKTIAREEGLRGLWKGTSPNV 183 Query: 530 LHSACFAAIGYCAFETARLMILKSYL 607 +A ++ + +LK+ L Sbjct: 184 ARNAIVNCAELVTYDLIKDTLLKADL 209 Score = 34.3 bits (77), Expect = 0.32 Identities = 34/166 (20%), Positives = 67/166 (40%), Gaps = 6/166 (3%) Frame = +2 Query: 116 PKELITQRLQSGAATG--RSWQVLLQILQT----DGFFGLYAGYAATLLRNLPAGVLSYS 277 P +++ R Q+ A G R ++ + +T +G GL+ G + + RN Sbjct: 136 PTDVVKVRFQAQARAGGGRRYRSTVDAYKTIAREEGLRGLWKGTSPNVARNAIVNCAELV 195 Query: 278 SFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTV 457 +++ +K L + P AG + + +P+DVVKTR M Q S + Sbjct: 196 TYDLIKDTLLKADLMTDDLPCHFTSAFG-AGFCTTVIASPVDVVKTRYMNSAPGQYS-SA 253 Query: 458 VGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMIL 595 ++ +EG +G P L + + + +E + ++ Sbjct: 254 GHCALTMLQKEGPRAFYKGFTPSFLRLGSWNVVMFVTYEQLKRALM 299
>UCP2_CANFA (Q9N2J1) Mitochondrial uncoupling protein 2 (UCP 2)| Length = 309 Score = 57.4 bits (137), Expect = 4e-08 Identities = 38/146 (26%), Positives = 66/146 (45%), Gaps = 3/146 (2%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 358 +L +++T+G LY+G A L R + + ++ +K F S + G +L G Sbjct: 66 ILTMVRTEGPRSLYSGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSEHAGI--GSRLLAG 123 Query: 359 ALAGAISAGLTTPLDVVKTRLMTRVGAQGSR---TVVGTMQEVIAEEGLMGLSRGIGPRV 529 + GA++ + P DVVK R + A R + V + + EEG GL +G P V Sbjct: 124 STTGALAVAVAQPTDVVKVRFQAQARAGSGRRYQSTVDAYKTIAREEGFRGLWKGTSPNV 183 Query: 530 LHSACFAAIGYCAFETARLMILKSYL 607 +A ++ + +LK+ L Sbjct: 184 ARNAIVNCAELVTYDLIKDALLKANL 209 Score = 39.3 bits (90), Expect = 0.010 Identities = 39/167 (23%), Positives = 72/167 (43%), Gaps = 7/167 (4%) Frame = +2 Query: 116 PKELITQRLQSGA--ATGRSWQVLLQILQT----DGFFGLYAGYAATLLRNLPAGVLSYS 277 P +++ R Q+ A +GR +Q + +T +GF GL+ G + + RN Sbjct: 136 PTDVVKVRFQAQARAGSGRRYQSTVDAYKTIAREEGFRGLWKGTSPNVARNAIVNCAELV 195 Query: 278 SFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTV 457 +++ +K AL K+N AG + + +P+DVVKTR M A G + Sbjct: 196 TYDLIKD-ALLKANLMTDDLPCHFTSAFGAGFCTTVIASPVDVVKTRYMN--SALGQYSS 252 Query: 458 VG-TMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMIL 595 G ++ +EG +G P L + + + +E + ++ Sbjct: 253 AGHCALTMLQKEGPRAFYKGFMPSFLRLGSWNVVMFVTYEQLKRALM 299
>TXTP_CAEEL (P34519) Putative tricarboxylate transport protein, mitochondrial| precursor (Citrate transport protein) (CTP) Length = 312 Score = 57.0 bits (136), Expect = 5e-08 Identities = 42/136 (30%), Positives = 66/136 (48%), Gaps = 3/136 (2%) Frame = +2 Query: 185 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGAL 364 Q + GFFGLY G + L ++P + +FEYLK+ A + NL+P +LCG Sbjct: 73 QTVNGHGFFGLYRGLSVLLYGSIPKSSFRFGTFEYLKSQAADERG--NLSPVMRLLCGLG 130 Query: 365 AGAISAGL-TTPLDVVKTRLMTRVG-AQGS-RTVVGTMQEVIAEEGLMGLSRGIGPRVLH 535 AG A TP++ VK + + G AQ + V + ++ EGL G+ +G+ + Sbjct: 131 AGLSEAVFAVTPMETVKVKFIHDQGLAQPKYKGFVHGVGCIVKAEGLGGIYKGVTATMAK 190 Query: 536 SACFAAIGYCAFETAR 583 AI + ET + Sbjct: 191 QGSNQAIRFFVMETLK 206 Score = 50.4 bits (119), Expect = 4e-06 Identities = 34/130 (26%), Positives = 60/130 (46%) Frame = +2 Query: 188 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 367 I++ +G G+Y G AT+ + + + E LK + N ++ L GA+A Sbjct: 171 IVKAEGLGGIYKGVTATMAKQGSNQAIRFFVMETLKDWYRGGDNTQPISKPIVGLMGAVA 230 Query: 368 GAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACF 547 GA S TP+DVVKTR M + A+ + + ++ +EG +G PR+ Sbjct: 231 GAASVYGNTPIDVVKTR-MQGLEAKKYKNTLDCAMQIWKKEGFFAFYKGTVPRLSRVCLD 289 Query: 548 AAIGYCAFET 577 I + +++ Sbjct: 290 VGITFMIYDS 299
>SFC1_YEAST (P33303) Succinate/fumarate mitochondrial transporter (Regulator of| acetyl-CoA synthetase activity) Length = 322 Score = 57.0 bits (136), Expect = 5e-08 Identities = 43/171 (25%), Positives = 73/171 (42%), Gaps = 15/171 (8%) Frame = +2 Query: 116 PKELITQRLQS----------GAATGRSWQVLLQILQTDGFFGLYAGYAATLLRNLPAGV 265 P E++ RLQ+ G + I++ +G LY G + T R Sbjct: 131 PMEVVKIRLQAQHLTPSEPNAGPKYNNAIHAAYTIVKEEGVSALYRGVSLTAARQATNQG 190 Query: 266 LSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRL-----MTR 430 +++ + LK F + L E+ G ++GAI PLD +KTRL ++ Sbjct: 191 ANFTVYSKLKEFLQNYHQMDVLPSWETSCIGLISGAIGPFSNAPLDTIKTRLQKDKSISL 250 Query: 431 VGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETAR 583 G + ++ +++ EEG L +GI PRV+ A A+ + +E R Sbjct: 251 EKQSGMKKIITIGAQLLKEEGFRALYKGITPRVMRVAPGQAVTFTVYEYVR 301 Score = 47.8 bits (112), Expect = 3e-05 Identities = 31/118 (26%), Positives = 55/118 (46%), Gaps = 8/118 (6%) Frame = +2 Query: 188 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 367 I Q +GF LY G A ++ +P + +SS+E+ + ++K + ++ G + + G A Sbjct: 62 IYQKEGFLALYKGLGAVVIGIIPKMAIRFSSYEFYRTLLVNKESG-IVSTGNTFVAGVGA 120 Query: 368 GAISAGL-TTPLDVVKTRLMTR-------VGAQGSRTVVGTMQEVIAEEGLMGLSRGI 517 G A L P++VVK RL + + ++ EEG+ L RG+ Sbjct: 121 GITEAVLVVNPMEVVKIRLQAQHLTPSEPNAGPKYNNAIHAAYTIVKEEGVSALYRGV 178 Score = 35.0 bits (79), Expect = 0.19 Identities = 23/92 (25%), Positives = 42/92 (45%), Gaps = 5/92 (5%) Frame = +2 Query: 335 PGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTV-----VGTMQEVIAEEGLM 499 P +++ G AG A PLD +K R+ G V + T + + +EG + Sbjct: 10 PAINLMAGGTAGLFEALCCHPLDTIKVRMQIYRRVAGIEHVKPPGFIKTGRTIYQKEGFL 69 Query: 500 GLSRGIGPRVLHSACFAAIGYCAFETARLMIL 595 L +G+G V+ AI + ++E R +++ Sbjct: 70 ALYKGLGAVVIGIIPKMAIRFSSYEFYRTLLV 101
>MFRN1_HUMAN (Q9NYZ2) Mitoferrin-1 (Mitochondrial iron transporter 1) (Solute| carrier family 25 member 37) (Mitochondria solute carrier protein) Length = 347 Score = 56.6 bits (135), Expect = 6e-08 Identities = 37/110 (33%), Positives = 58/110 (52%), Gaps = 3/110 (2%) Frame = +2 Query: 110 MVPKELITQRLQSGAATGRSW-QVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFE 286 M P E++ QRLQ + RS + + +T+G Y Y L N+P + + ++E Sbjct: 161 MNPAEVVKQRLQMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYE 220 Query: 287 YLKAFALSKSNAPNLT--PGESVLCGALAGAISAGLTTPLDVVKTRLMTR 430 +L+ + P+ T P ++ G LAGA++A TTPLDV KT L T+ Sbjct: 221 FLQ-----EQVNPHRTYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQ 265 Score = 32.0 bits (71), Expect = 1.6 Identities = 17/78 (21%), Positives = 40/78 (51%), Gaps = 2/78 (2%) Frame = +2 Query: 356 GALAGAISAGLTTPLDVVKTRLMTRVGAQGSR--TVVGTMQEVIAEEGLMGLSRGIGPRV 529 GA+AG + + P+D VKTR+ + ++ ++ G +++++ EG RG+ + Sbjct: 52 GAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGVNVMI 111 Query: 530 LHSACFAAIGYCAFETAR 583 + + A+ + +E + Sbjct: 112 MGAGPAHAMYFACYENMK 129
>MCAT_RAT (P97521) Mitochondrial carnitine/acylcarnitine carrier protein| (Carnitine/acylcarnitine translocase) (CAC) (Solute carrier family 25 member 20) Length = 301 Score = 56.2 bits (134), Expect = 8e-08 Identities = 42/157 (26%), Positives = 75/157 (47%), Gaps = 11/157 (7%) Frame = +2 Query: 110 MVPKELITQRLQSGAATGRS-----WQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSY 274 M P E I LQ A++G++ ++ Q G G Y G A TL+R++PA + + Sbjct: 128 MTPGERIKCLLQIQASSGKNKYSGTLDCAKKLYQEFGIRGFYKGTALTLMRDVPASGMYF 187 Query: 275 SSFEYLK-AFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSR 451 ++E+LK F + +L+ ++ G G + + P DV+K+R T + Sbjct: 188 MTYEWLKNLFTPQGKSVHDLSVPRVLVAGGFRGIFNWVVAIPPDVLKSRFQTAPPGKYPN 247 Query: 452 TVVGTMQEVIAEEGLMGLSRGIGPRVL-----HSACF 547 ++E+I EEG+ L +G ++ ++ACF Sbjct: 248 GFRDVLRELIREEGVTSLYKGFNAVMIRAFPANAACF 284 Score = 34.7 bits (78), Expect = 0.25 Identities = 23/87 (26%), Positives = 39/87 (44%), Gaps = 10/87 (11%) Frame = +2 Query: 329 LTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRT-----VVGTMQEVIAEEG 493 ++P +++L G G + PLD VK RL T+ + + + ++ + EG Sbjct: 8 ISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTIDCFRKTLFREG 67 Query: 494 LMGLSRG-----IGPRVLHSACFAAIG 559 + GL RG IG + + CF G Sbjct: 68 ITGLYRGMAAPIIGVTPMFAVCFFGFG 94
>CMC2_CAEEL (Q20799) Probable calcium-binding mitochondrial carrier F55A11.4| Length = 588 Score = 56.2 bits (134), Expect = 8e-08 Identities = 33/142 (23%), Positives = 65/142 (45%), Gaps = 1/142 (0%) Frame = +2 Query: 182 LQILQTDGFF-GLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 358 L++L +G + G +++ P + + ++ LK K ++ E + G Sbjct: 292 LKLLHAEGGIKSFWRGNGINVIKIAPESAIKFMCYDQLKRLIQKKKGNEEISTFERLCAG 351 Query: 359 ALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHS 538 + AGAIS P++V+KTRL R Q R ++ ++ +EG+ +G P ++ Sbjct: 352 SAAGAISQSTIYPMEVMKTRLALRKTGQLDRGIIHFAHKMYTKEGIRCFYKGYLPNLIGI 411 Query: 539 ACFAAIGYCAFETARLMILKSY 604 +A I +ET + ++ Y Sbjct: 412 IPYAGIDLAIYETLKRTYVRYY 433 Score = 46.2 bits (108), Expect = 8e-05 Identities = 36/134 (26%), Positives = 56/134 (41%), Gaps = 6/134 (4%) Frame = +2 Query: 200 DGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVL--CGALAGA 373 +G Y GY L+ +P + + +E LK + + PG L CG + Sbjct: 395 EGIRCFYKGYLPNLIGIIPYAGIDLAIYETLKRTYVRYYETNSSEPGVLALLACGTCSST 454 Query: 374 ISAGLTTPLDVVKTRL----MTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSA 541 + P +V+TRL +TR Q T+ G + ++ EG+ G RGI P L Sbjct: 455 CGQLSSYPFALVRTRLQALSITRYSPQPD-TMFGQFKYILQNEGVTGFYRGITPNFLKVI 513 Query: 542 CFAAIGYCAFETAR 583 +I Y +E R Sbjct: 514 PAVSISYVVYEKVR 527 Score = 37.7 bits (86), Expect = 0.029 Identities = 23/84 (27%), Positives = 39/84 (46%) Frame = +2 Query: 347 VLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPR 526 ++ G AGA+S T P D +K L V+ ++ + AE G+ RG G Sbjct: 252 LVAGGAAGAVSRTCTAPFDRIKVYLQVNSSKTNRLGVMSCLKLLHAEGGIKSFWRGNGIN 311 Query: 527 VLHSACFAAIGYCAFETARLMILK 598 V+ A +AI + ++ + +I K Sbjct: 312 VIKIAPESAIKFMCYDQLKRLIQK 335 Score = 30.0 bits (66), Expect = 6.1 Identities = 21/66 (31%), Positives = 31/66 (46%), Gaps = 6/66 (9%) Frame = +2 Query: 116 PKELITQRLQSGAATGRSWQV------LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYS 277 P L+ RLQ+ + T S Q ILQ +G G Y G L+ +PA +SY Sbjct: 462 PFALVRTRLQALSITRYSPQPDTMFGQFKYILQNEGVTGFYRGITPNFLKVIPAVSISYV 521 Query: 278 SFEYLK 295 +E ++ Sbjct: 522 VYEKVR 527
>UCP3_RAT (P56499) Mitochondrial uncoupling protein 3 (UCP 3)| Length = 308 Score = 55.5 bits (132), Expect = 1e-07 Identities = 40/148 (27%), Positives = 68/148 (45%), Gaps = 5/148 (3%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 358 +L +++T+G Y+G A L R + + ++ +K F K + + +L G Sbjct: 62 ILTMVRTEGPRSPYSGLVAGLHRQMSFASIRIGLYDSVKQFYTPKGT-DHSSVAIRILAG 120 Query: 359 ALAGAISAGLTTPLDVVKTRL--MTRVGAQGSRTVVGTM---QEVIAEEGLMGLSRGIGP 523 GA++ P DVVK R M R+G G R GTM + + EEG+ GL +G P Sbjct: 121 CTTGAMAVTCAQPTDVVKVRFQAMIRLGTGGERKYRGTMDAYRTIAREEGVRGLWKGTWP 180 Query: 524 RVLHSACFAAIGYCAFETARLMILKSYL 607 + +A ++ + +L S+L Sbjct: 181 NITRNAIVNCAEMVTYDIIKEKLLDSHL 208 Score = 37.0 bits (84), Expect = 0.050 Identities = 31/137 (22%), Positives = 58/137 (42%) Frame = +2 Query: 188 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 367 I + +G GL+ G + RN +++ +K L + P V A Sbjct: 165 IAREEGVRGLWKGTWPNITRNAIVNCAEMVTYDIIKEKLLDSHLFTDNFPCHFVSAFG-A 223 Query: 368 GAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACF 547 G + + +P+DVVKTR M + R+ + M ++A+EG +G P L + Sbjct: 224 GFCATVVASPVDVVKTRYMNAPPGR-YRSPLHCMLRMVAQEGPTAFYKGFMPSFLRLGSW 282 Query: 548 AAIGYCAFETARLMILK 598 + + +E + ++K Sbjct: 283 NVMMFVTYEQLKRALMK 299
>YEA6_YEAST (P39953) Putative mitochondrial carrier YEL006W| Length = 335 Score = 55.5 bits (132), Expect = 1e-07 Identities = 37/120 (30%), Positives = 64/120 (53%), Gaps = 5/120 (4%) Frame = +2 Query: 188 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSK-SNAPNLTPGESVLCGAL 364 I + +G GLY G T+L +P ++ +S +++ + +++ ++P L+ S + Sbjct: 91 IFKDEGAAGLYKGLQPTVLGYIPTLMIYFSVYDFCRKYSVDIFPHSPFLSNASSAIT--- 147 Query: 365 AGAISAGLTTPLDVVKTRLMTRVGAQGSRT----VVGTMQEVIAEEGLMGLSRGIGPRVL 532 AGAIS T P+ VVKTRLM + G T + T +++I +EG L G+ P +L Sbjct: 148 AGAISTVATNPIWVVKTRLMLQTGIGKYSTHYKGTIDTFRKIIQQEGAKALYAGLVPALL 207 Score = 48.5 bits (114), Expect = 2e-05 Identities = 36/109 (33%), Positives = 50/109 (45%), Gaps = 6/109 (5%) Frame = +2 Query: 326 NLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTR------VGAQGSRTVVGTMQEVIAE 487 N P + + GAL+GA+SA L P DV KTRL + +Q + GT + + Sbjct: 35 NADPRVAAISGALSGALSAMLVCPFDVAKTRLQAQGLQNMTHQSQHYKGFFGTFATIFKD 94 Query: 488 EGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMILKSYLESCERKAAD 634 EG GL +G+ P VL GY LMI S + C + + D Sbjct: 95 EGAAGLYKGLQPTVL--------GY----IPTLMIYFSVYDFCRKYSVD 131 Score = 40.0 bits (92), Expect = 0.006 Identities = 23/67 (34%), Positives = 37/67 (55%), Gaps = 5/67 (7%) Frame = +2 Query: 116 PKELITQRLQSGAATGRSWQVLLQIL-----QTDGFFGLYAGYAATLLRNLPAGVLSYSS 280 P E++ R+Q + + Q L L + +GF G Y+G+A L+R +PA V++ S Sbjct: 263 PHEILRTRMQLKSDLPNTVQRHLLPLIKITYRQEGFAGFYSGFATNLVRTVPAAVVTLVS 322 Query: 281 FEYLKAF 301 FEY K + Sbjct: 323 FEYSKKY 329
>CMC3_CAEEL (Q19529) Probable calcium-binding mitochondrial carrier F17E5.2| Length = 531 Score = 55.5 bits (132), Expect = 1e-07 Identities = 34/139 (24%), Positives = 62/139 (44%) Frame = +2 Query: 203 GFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISA 382 G + G +++ P + + ++ +K + L+ E +L G+ AGAIS Sbjct: 296 GIKSFWRGNGINVIKIAPESAMKFMCYDQIKRWMQEYKGGAELSTIERLLAGSSAGAISQ 355 Query: 383 GLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGY 562 P++V+KTRL R Q + + ++ +EG+ +G P +L +A I Sbjct: 356 TAIYPMEVMKTRLALRRTGQLDKGMFHFAHKMYTKEGIKCFYKGYLPNLLGIIPYAGIDL 415 Query: 563 CAFETARLMILKSYLESCE 619 +E+ + M K Y E E Sbjct: 416 TVYESLKSMYTKYYTEHTE 434 Score = 52.4 bits (124), Expect = 1e-06 Identities = 43/165 (26%), Positives = 70/165 (42%), Gaps = 9/165 (5%) Frame = +2 Query: 116 PKELITQRL---QSGAATGRSWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFE 286 P E++ RL ++G + ++ +G Y GY LL +P + + +E Sbjct: 360 PMEVMKTRLALRRTGQLDKGMFHFAHKMYTKEGIKCFYKGYLPNLLGIIPYAGIDLTVYE 419 Query: 287 YLKAFALSKSNAPNLTPGESVL--CGALAGAISAGLTTPLDVVKTRLMTRV----GAQGS 448 LK+ +K + PG L CG + + PL +V+TRL R + Sbjct: 420 SLKSM-YTKYYTEHTEPGVLALLACGTCSSTCGQLASYPLALVRTRLQARAISPKNSTQP 478 Query: 449 RTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETAR 583 T+VG + ++ EG GL RGI P + +I Y +E R Sbjct: 479 DTMVGQFKHILQTEGFTGLYRGITPNFMKVIPAVSISYVVYEKVR 523 Score = 33.9 bits (76), Expect = 0.42 Identities = 21/76 (27%), Positives = 35/76 (46%) Frame = +2 Query: 347 VLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPR 526 ++ G +AGA+S T P D +K L VV + + AE G+ RG G Sbjct: 248 LVAGGVAGAMSRTCTAPFDRIKVYLQVNSTKTNKLGVVSCVHLLHAEGGIKSFWRGNGIN 307 Query: 527 VLHSACFAAIGYCAFE 574 V+ A +A+ + ++ Sbjct: 308 VIKIAPESAMKFMCYD 323
>YG5F_YEAST (P53320) Putative mitochondrial carrier YGR257C| Length = 366 Score = 55.1 bits (131), Expect = 2e-07 Identities = 39/145 (26%), Positives = 70/145 (48%), Gaps = 8/145 (5%) Frame = +2 Query: 173 QVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVL 352 + +I +G L+ G + TLL +PA ++ +S +EY++ + S P L P + Sbjct: 107 EAFTKIASVEGITSLWRGISLTLLMAIPANMVYFSGYEYIRDVSPIASTYPTLNP---LF 163 Query: 353 CGALAGAISAGLTTPLDVVKTRLMTRVGAQGS----RTVVGTMQEVIAEEGLMGLSR--- 511 CGA+A +A PL++VKT+L + + S V + E E ++G SR Sbjct: 164 CGAIARVFAATSIAPLELVKTKLQSIPRSSKSTKTWMMVKDLLNETRQEMKMVGPSRALF 223 Query: 512 -GIGPRVLHSACFAAIGYCAFETAR 583 G+ + F+AI + ++E + Sbjct: 224 KGLEITLWRDVPFSAIYWSSYELCK 248 Score = 49.3 bits (116), Expect = 1e-05 Identities = 51/203 (25%), Positives = 83/203 (40%), Gaps = 26/203 (12%) Frame = +2 Query: 53 PFLVPPLXXXXXXXXXXXXMVPKELITQRLQS---GAATGRSWQVLLQIL----QTDGFF 211 P L P + P EL+ +LQS + + ++W ++ +L Q Sbjct: 157 PTLNPLFCGAIARVFAATSIAPLELVKTKLQSIPRSSKSTKTWMMVKDLLNETRQEMKMV 216 Query: 212 G----LYAGYAATLLRNLPAGVLSYSSFEYLKA--------FALSKSNAPNLTPGESVLC 355 G L+ G TL R++P + +SS+E K FA +N + S Sbjct: 217 GPSRALFKGLEITLWRDVPFSAIYWSSYELCKERLWLDSTRFASKDANWVHFI--NSFAS 274 Query: 356 GALAGAISAGLTTPLDVVKTRLMTRV-------GAQGSRTVVGTMQEVIAEEGLMGLSRG 514 G ++G I+A T P DV KTR + G SR + ++ + EGL L G Sbjct: 275 GCISGMIAAICTHPFDVGKTRWQISMMNNSDPKGGNRSRNMFKFLETIWRTEGLAALYTG 334 Query: 515 IGPRVLHSACFAAIGYCAFETAR 583 + RV+ AI ++E ++ Sbjct: 335 LAARVIKIRPSCAIMISSYEISK 357
>DNC_HUMAN (Q9HC21) Mitochondrial deoxynucleotide carrier (Solute carrier| family 25 member 19) (Mitochondrial uncoupling protein 1) Length = 320 Score = 54.3 bits (129), Expect = 3e-07 Identities = 40/132 (30%), Positives = 65/132 (49%), Gaps = 13/132 (9%) Frame = +2 Query: 218 YAGYAATLLRNLPAGVLS---YSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGL 388 Y G A TL+ P L YSS ++L +A+ N +++LCG+ AG IS L Sbjct: 175 YKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENL-QNLLCGSGAGVISKTL 233 Query: 389 TTPLDVVKTRLMTRVGAQGSRTVVGTM----------QEVIAEEGLMGLSRGIGPRVLHS 538 T PLD+ K RL G + +R G + ++V+ +EG +G +G+ P +L + Sbjct: 234 TYPLDLFKKRLQVG-GFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKA 292 Query: 539 ACFAAIGYCAFE 574 A + ++E Sbjct: 293 ALSTGFMFFSYE 304 Score = 43.5 bits (101), Expect = 5e-04 Identities = 32/141 (22%), Positives = 59/141 (41%), Gaps = 4/141 (2%) Frame = +2 Query: 173 QVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVL 352 Q QILQ +G + G+ + ++ G + + SFE L S + Sbjct: 64 QASRQILQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFV 123 Query: 353 CGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIA----EEGLMGLSRGIG 520 CG LA ++ P+DV++TR AQG V T++ + EG +G+ Sbjct: 124 CGGLAACMATLTVHPVDVLRTRF----AAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLA 179 Query: 521 PRVLHSACFAAIGYCAFETAR 583 P ++ +A + + + + + Sbjct: 180 PTLIAIFPYAGLQFSCYSSLK 200 Score = 33.9 bits (76), Expect = 0.42 Identities = 23/95 (24%), Positives = 45/95 (47%), Gaps = 7/95 (7%) Frame = +2 Query: 311 KSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTR----VGAQGSRTVVGTMQ-- 472 K + N T + + G+++G ++ L +P DV+K R + + S G +Q Sbjct: 7 KPDGRNNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQAS 66 Query: 473 -EVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFE 574 +++ EEG +G P + S + A+ + +FE Sbjct: 67 RQILQEEGPTAFWKGHVPAQILSIGYGAVQFLSFE 101
>YHM1_YEAST (P38988) Putative mitochondrial carrier protein YHM1/SHM1| Length = 300 Score = 53.1 bits (126), Expect = 7e-07 Identities = 28/117 (23%), Positives = 55/117 (47%) Frame = +2 Query: 182 LQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGA 361 ++IL+ +G F LY G+ T RN P + + K + L + T ++ + Sbjct: 159 IKILRDEGLFNLYRGWGWTAARNAPGSFALFGGNAFAKEYILGLKDYSQATWSQNFISSI 218 Query: 362 LAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVL 532 + S ++ PLDV+KTR+ R + + ++ + EG+ +G+ P++L Sbjct: 219 VGACSSLIVSAPLDVIKTRIQNR-NFDNPESGLRIVKNTLKNEGVTAFFKGLTPKLL 274
>GHC1_PONPY (Q5RD81) Mitochondrial glutamate carrier 1 (GC-1) (Glutamate/H(+)| symporter 1) (Solute carrier family 25 member 22) Length = 323 Score = 52.8 bits (125), Expect = 9e-07 Identities = 39/125 (31%), Positives = 59/125 (47%), Gaps = 5/125 (4%) Frame = +2 Query: 173 QVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFA--LSKSNAPNLTPGES 346 Q+ +L++ G GLY G ATLLR++P V+ + F L S+ +P S Sbjct: 172 QLTRDLLRSRGIAGLYKGLGATLLRDVPLSVVYFPLFANLNQLGRPASEEKSPFYV---S 228 Query: 347 VLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTM---QEVIAEEGLMGLSRGI 517 L G +AG+ +A P DVVKTRL + T G + ++++ EG +G Sbjct: 229 FLAGCVAGSAAAVAVNPCDVVKTRLQSLQRGVNEDTYSGILDCARKILRHEGPSAFLKGA 288 Query: 518 GPRVL 532 R L Sbjct: 289 YCRAL 293 Score = 45.8 bits (107), Expect = 1e-04 Identities = 40/183 (21%), Positives = 80/183 (43%), Gaps = 31/183 (16%) Frame = +2 Query: 116 PKELITQRLQSGAATGRSW----QVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSF 283 P +L RLQ+ R + L++ ++++G+FG+Y G A L P + ++ Sbjct: 28 PIDLAKTRLQNQQNGQRMYTSMSDCLIKTIRSEGYFGMYRGAAVNLTLVTPEKAIKLAAN 87 Query: 284 EYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMT------------ 427 ++ + LSK + LT + +L G AG +TTP++++K +L Sbjct: 88 DFFR-HQLSK-DGQKLTLLKEMLAGCGAGTCQVIVTTPMEMLKIQLQDAGRIAAQRKILA 145 Query: 428 ---RVGAQGSR------------TVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGY 562 ++ AQG T + ++++ G+ GL +G+G +L + + + Sbjct: 146 AQGQLSAQGGAQPSVEAPAAPRPTAIQLTRDLLRSRGIAGLYKGLGATLLRDVPLSVVYF 205 Query: 563 CAF 571 F Sbjct: 206 PLF 208 Score = 32.0 bits (71), Expect = 1.6 Identities = 18/54 (33%), Positives = 26/54 (48%), Gaps = 1/54 (1%) Frame = +2 Query: 356 GALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVG-TMQEVIAEEGLMGLSRG 514 G +AG I P+D+ KTRL + Q T + + + I EG G+ RG Sbjct: 15 GGIAGLIGVTCVFPIDLAKTRLQNQQNGQRMYTSMSDCLIKTIRSEGYFGMYRG 68
>DNC_PONPY (Q5NVC1) Mitochondrial deoxynucleotide carrier (Solute carrier| family 25 member 19) Length = 320 Score = 52.8 bits (125), Expect = 9e-07 Identities = 39/121 (32%), Positives = 61/121 (50%), Gaps = 13/121 (10%) Frame = +2 Query: 218 YAGYAATLLRNLPAGVLS---YSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGL 388 Y G A TL+ P L YSS ++L +A+ N +++LCG+ AG IS L Sbjct: 175 YKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENL-QNLLCGSGAGVISKTL 233 Query: 389 TTPLDVVKTRLMTRVGAQGSRTVVGTM----------QEVIAEEGLMGLSRGIGPRVLHS 538 T PLD+ K RL G + +R G + ++V+ +EG +G +G+ P +L + Sbjct: 234 TYPLDLFKKRLQVG-GFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKA 292 Query: 539 A 541 A Sbjct: 293 A 293 Score = 41.6 bits (96), Expect = 0.002 Identities = 32/141 (22%), Positives = 58/141 (41%), Gaps = 4/141 (2%) Frame = +2 Query: 173 QVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVL 352 Q QILQ +G + G+ + ++ G + + SFE L S + Sbjct: 64 QASRQILQEEGPTAFWKGHIPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFV 123 Query: 353 CGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIA----EEGLMGLSRGIG 520 CG LA ++ P+DV++TR AQG V T+ + EG +G+ Sbjct: 124 CGGLAACMATLTVHPVDVLRTRF----AAQGEPKVYNTLCHAVGTMYRSEGPQVFYKGLA 179 Query: 521 PRVLHSACFAAIGYCAFETAR 583 P ++ +A + + + + + Sbjct: 180 PTLIAIFPYAGLQFSCYSSLK 200 Score = 33.1 bits (74), Expect = 0.72 Identities = 21/95 (22%), Positives = 45/95 (47%), Gaps = 7/95 (7%) Frame = +2 Query: 311 KSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRL------MTRVGAQGS-RTVVGTM 469 K + N T + + G+++G ++ L +P DV+K R ++R ++ Sbjct: 7 KPDGRNNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPNAKYHGILQAS 66 Query: 470 QEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFE 574 ++++ EEG +G P + S + A+ + +FE Sbjct: 67 RQILQEEGPTAFWKGHIPAQILSIGYGAVQFLSFE 101
>DNC_MACFA (Q5IS35) Mitochondrial deoxynucleotide carrier (Solute carrier| family 25 member 19) Length = 320 Score = 52.8 bits (125), Expect = 9e-07 Identities = 39/121 (32%), Positives = 61/121 (50%), Gaps = 13/121 (10%) Frame = +2 Query: 218 YAGYAATLLRNLPAGVLS---YSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGL 388 Y G A TL+ P L YSS ++L +A+ N +++LCG+ AG IS L Sbjct: 175 YKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAMPAEGKKNENL-QNLLCGSGAGVISKTL 233 Query: 389 TTPLDVVKTRLMTRVGAQGSRTVVGTM----------QEVIAEEGLMGLSRGIGPRVLHS 538 T PLD+ K RL G + +R G + ++V+ +EG +G +G+ P +L + Sbjct: 234 TYPLDLFKKRLQVG-GFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKA 292 Query: 539 A 541 A Sbjct: 293 A 293 Score = 44.3 bits (103), Expect = 3e-04 Identities = 32/142 (22%), Positives = 59/142 (41%), Gaps = 4/142 (2%) Frame = +2 Query: 170 WQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESV 349 +Q QILQ +G + G+ + ++ G + + SFE L S Sbjct: 63 FQASRQILQEEGLTAFWKGHIPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHF 122 Query: 350 LCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIA----EEGLMGLSRGI 517 +CG LA + P+DV++TR AQG V T++ + EG +G+ Sbjct: 123 VCGGLAACTATLTVHPVDVLRTRF----AAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGL 178 Query: 518 GPRVLHSACFAAIGYCAFETAR 583 P ++ +A + + + + + Sbjct: 179 APTLIAIFPYAGLQFSCYSSLK 200 Score = 36.2 bits (82), Expect = 0.085 Identities = 22/95 (23%), Positives = 44/95 (46%), Gaps = 7/95 (7%) Frame = +2 Query: 311 KSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRT-------VVGTM 469 K + N T + + G+++G ++ L +P DV+K R + R + Sbjct: 7 KPDGRNNTKLQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRRDPNAKYHGIFQAS 66 Query: 470 QEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFE 574 ++++ EEGL +G P + S + A+ + +FE Sbjct: 67 RQILQEEGLTAFWKGHIPAQILSIGYGAVQFLSFE 101
>DNC_MOUSE (Q9DAM5) Mitochondrial deoxynucleotide carrier (Solute carrier| family 25 member 19) Length = 318 Score = 52.4 bits (124), Expect = 1e-06 Identities = 37/135 (27%), Positives = 64/135 (47%), Gaps = 12/135 (8%) Frame = +2 Query: 173 QVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFA--LSKSNAPNLTPGES 346 + + + +T+G F Y G T++ P L +S + LK L + ++ Sbjct: 160 EAIRTMYKTEGPFVFYKGLTPTVIAIFPYAGLQFSCYRSLKRAYDWLIPPDGKQTGNLKN 219 Query: 347 VLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTM----------QEVIAEEGL 496 +LCG +G IS T PLD++K RL G + +R+ G + Q+V+ EEG Sbjct: 220 LLCGCGSGVISKTFTYPLDLIKKRLQVG-GFEHARSAFGQVRSYRGLLDLTQQVLQEEGT 278 Query: 497 MGLSRGIGPRVLHSA 541 G +G+ P ++ +A Sbjct: 279 RGFFKGLSPSLMKAA 293 Score = 42.4 bits (98), Expect = 0.001 Identities = 31/142 (21%), Positives = 60/142 (42%), Gaps = 4/142 (2%) Frame = +2 Query: 170 WQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESV 349 +Q QILQ +G + G+ + ++ G + + +FE L + Sbjct: 63 FQAAKQILQEEGPRAFWKGHVPAQILSIGYGAVQFLAFEELTELLYQANLYQTHQFSAHF 122 Query: 350 LCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVI----AEEGLMGLSRGI 517 +CG L+ + P+DV++TRL AQG + ++E I EG +G+ Sbjct: 123 VCGGLSAGTATLTVHPVDVLRTRL----AAQGEPKIYNNLREAIRTMYKTEGPFVFYKGL 178 Query: 518 GPRVLHSACFAAIGYCAFETAR 583 P V+ +A + + + + + Sbjct: 179 TPTVIAIFPYAGLQFSCYRSLK 200 Score = 35.0 bits (79), Expect = 0.19 Identities = 23/96 (23%), Positives = 47/96 (48%), Gaps = 7/96 (7%) Frame = +2 Query: 341 ESVLCGALAGAISAGLTTPLDVVKTRLMTRV----GAQGSRTVVGTMQ---EVIAEEGLM 499 E + G+++G ++ L +PLDV+K R ++ + + G Q +++ EEG Sbjct: 17 EVAVAGSVSGFVTRALISPLDVIKIRFQLQIERLCPSDPNAKYHGIFQAAKQILQEEGPR 76 Query: 500 GLSRGIGPRVLHSACFAAIGYCAFETARLMILKSYL 607 +G P + S + A+ + AFE ++ ++ L Sbjct: 77 AFWKGHVPAQILSIGYGAVQFLAFEELTELLYQANL 112
>UCP3_BOVIN (O77792) Mitochondrial uncoupling protein 3 (UCP 3)| Length = 311 Score = 52.4 bits (124), Expect = 1e-06 Identities = 37/126 (29%), Positives = 61/126 (48%), Gaps = 5/126 (3%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 358 +L +++T+G LY+G A L R + + ++ +K F K + + + +L G Sbjct: 65 ILTMVRTEGPRSLYSGLVAGLQRQMSFASIRIGLYDSVKQFYTPK-GSDHSSIITRILAG 123 Query: 359 ALAGAISAGLTTPLDVVKTRLMT--RVGAQGSRTVVGTM---QEVIAEEGLMGLSRGIGP 523 GA++ P DVVK R G G+R GTM + + EEG+ GL +GI P Sbjct: 124 CTTGAMAVTCAQPTDVVKIRFQASMHTGLGGNRKYSGTMDAYRTIAREEGVRGLWKGILP 183 Query: 524 RVLHSA 541 + +A Sbjct: 184 NITRNA 189 Score = 36.6 bits (83), Expect = 0.065 Identities = 36/169 (21%), Positives = 68/169 (40%), Gaps = 8/169 (4%) Frame = +2 Query: 116 PKELITQRLQSGAATG----RSWQVLLQILQT----DGFFGLYAGYAATLLRNLPAGVLS 271 P +++ R Q+ TG R + + +T +G GL+ G + RN Sbjct: 136 PTDVVKIRFQASMHTGLGGNRKYSGTMDAYRTIAREEGVRGLWKGILPNITRNAIVNCGE 195 Query: 272 YSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSR 451 +++ +K L + P V AG + + +P+DVVKTR M Q Sbjct: 196 MVTYDIIKEKLLDYHLLTDNFPCHFVSAFG-AGFCATLVASPVDVVKTRYMNSPPGQ-YH 253 Query: 452 TVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMILK 598 + M +++ +EG +G P L + + + +E + ++K Sbjct: 254 SPFDCMLKMVTQEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQMKRALMK 302
>GHC1_HUMAN (Q9H936) Mitochondrial glutamate carrier 1 (GC-1) (Glutamate/H(+)| symporter 1) (Solute carrier family 25 member 22) Length = 323 Score = 52.4 bits (124), Expect = 1e-06 Identities = 39/125 (31%), Positives = 59/125 (47%), Gaps = 5/125 (4%) Frame = +2 Query: 173 QVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFA--LSKSNAPNLTPGES 346 Q+ +L++ G GLY G ATLLR++P V+ + F L S+ +P S Sbjct: 172 QLTRDLLRSRGIAGLYKGLGATLLRDVPFSVVYFPLFANLNQLGRPASEEKSPFYV---S 228 Query: 347 VLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTM---QEVIAEEGLMGLSRGI 517 L G +AG+ +A P DVVKTRL + T G + ++++ EG +G Sbjct: 229 FLAGCVAGSAAAVAVNPCDVVKTRLQSLQRGVNEDTYSGILDCARKILRHEGPSAFLKGA 288 Query: 518 GPRVL 532 R L Sbjct: 289 YCRAL 293 Score = 47.0 bits (110), Expect = 5e-05 Identities = 42/183 (22%), Positives = 80/183 (43%), Gaps = 31/183 (16%) Frame = +2 Query: 116 PKELITQRLQSGAATGRSW----QVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSF 283 P +L RLQ+ R + L++ ++++G+FG+Y G A L P + ++ Sbjct: 28 PIDLAKTRLQNQQNGQRVYTSMSDCLIKTVRSEGYFGMYRGAAVNLTLVTPEKAIKLAAN 87 Query: 284 EYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTR---------VG 436 ++ + LSK + LT + +L G AG +TTP++++K +L + Sbjct: 88 DFFR-HQLSK-DGQKLTLLKEMLAGCGAGTCQVIVTTPMEMLKIQLQDAGRIAAQRKILA 145 Query: 437 AQGSRTVVGTMQ------------------EVIAEEGLMGLSRGIGPRVLHSACFAAIGY 562 AQG + G Q +++ G+ GL +G+G +L F+ + + Sbjct: 146 AQGQLSAQGGAQPSVEAPAAPRPTATQLTRDLLRSRGIAGLYKGLGATLLRDVPFSVVYF 205 Query: 563 CAF 571 F Sbjct: 206 PLF 208 Score = 31.2 bits (69), Expect = 2.7 Identities = 17/54 (31%), Positives = 26/54 (48%), Gaps = 1/54 (1%) Frame = +2 Query: 356 GALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVG-TMQEVIAEEGLMGLSRG 514 G +AG I P+D+ KTRL + Q T + + + + EG G+ RG Sbjct: 15 GGIAGLIGVTCVFPIDLAKTRLQNQQNGQRVYTSMSDCLIKTVRSEGYFGMYRG 68
>TXTP_YEAST (P38152) Tricarboxylate transport protein (Citrate transport| protein) (CTP) Length = 299 Score = 51.6 bits (122), Expect = 2e-06 Identities = 35/138 (25%), Positives = 61/138 (44%), Gaps = 3/138 (2%) Frame = +2 Query: 188 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPN---LTPGESVLCG 358 +++ GF GLY G +R + + +K +++P L+ G + L G Sbjct: 162 LVRDKGFSGLYRGVLPVSMRQAANQAVRLGCYNKIKTLIQDYTDSPKDKPLSSGLTFLVG 221 Query: 359 ALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHS 538 A +G ++ T PLD VKTR+ + + S T + + EEGL +G PR+ Sbjct: 222 AFSGIVTVYSTMPLDTVKTRMQSLDSTKYSST-MNCFATIFKEEGLKTFWKGATPRLGRL 280 Query: 539 ACFAAIGYCAFETARLMI 592 I + +E +M+ Sbjct: 281 VLSGGIVFTIYEKVLVML 298 Score = 41.2 bits (95), Expect = 0.003 Identities = 27/99 (27%), Positives = 49/99 (49%), Gaps = 1/99 (1%) Frame = +2 Query: 308 SKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRL-MTRVGAQGSRTVVGTMQEVIA 484 SK+ ++ P S L G+LAGA A +T P + KTRL + ++ SR + + + Sbjct: 3 SKATKSDVDPLHSFLAGSLAGAAEACITYPFEFAKTRLQLIDKASKASRNPLVLIYKTAK 62 Query: 485 EEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMILKS 601 +G+ + G ++ + A I + F+T + M+ S Sbjct: 63 TQGIGSIYVGCPAFIIGNTAKAGIRFLGFDTIKDMLRDS 101
>DIC_HUMAN (Q9UBX3) Mitochondrial dicarboxylate carrier (Solute carrier family| 25 member 10) Length = 287 Score = 51.2 bits (121), Expect = 3e-06 Identities = 43/168 (25%), Positives = 75/168 (44%), Gaps = 6/168 (3%) Frame = +2 Query: 116 PKELITQRLQSGAATG-RSWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYL 292 P +L+ LQ+ R + L++++TDG LY+G +A+L R + + ++ +E + Sbjct: 26 PLDLLKVHLQTQQEVKLRMTGMALRVVRTDGILALYSGLSASLCRQMTYSLTRFAIYETV 85 Query: 293 KAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVG-AQGSRT----V 457 + S P L E VL G+++G + TP D+V R+ V QG R Sbjct: 86 RDRVAKGSQGP-LPFHEKVLLGSVSGLAGGFVGTPADLVNVRMQNDVKLPQGQRRNYAHA 144 Query: 458 VGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMILKS 601 + + V EEGL L G A ++ A+ ++L + Sbjct: 145 LDGLYRVAREEGLRRLFSGATMASSRGALVTVGQLSCYDQAKQLVLST 192 Score = 30.0 bits (66), Expect = 6.1 Identities = 24/86 (27%), Positives = 36/86 (41%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 358 L ++ + +G L++G R V S ++ K LS + V Sbjct: 148 LYRVAREEGLRRLFSGATMASSRGALVTVGQLSCYDQAKQLVLSTGYLSDNIFTHFV-AS 206 Query: 359 ALAGAISAGLTTPLDVVKTRLMTRVG 436 +AG + L PLDV+KTRLM G Sbjct: 207 FIAGGCATFLCQPLDVLKTRLMNSKG 232
>MCATL_MOUSE (Q8BL03) Mitchondrial carnitine/acylcarnitine carrier protein CACL| (CACT-like) (Solute carrier family 25 member 29) Length = 306 Score = 50.8 bits (120), Expect = 3e-06 Identities = 47/160 (29%), Positives = 75/160 (46%), Gaps = 13/160 (8%) Frame = +2 Query: 116 PKELITQRLQSGAATGR-----SWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSS 280 P EL RLQ A S L+QI + +G G+ G +TLLR P+ + + + Sbjct: 112 PMELAKTRLQLQAVGPARTYKGSLDCLVQIYRHEGLRGINRGMVSTLLRETPSFGVYFLT 171 Query: 281 FEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGS---R 451 ++ + A+ L + +L G +G S T P+DVVK+RL G QG+ R Sbjct: 172 YDVMTR-AMGCEPGDRLLVPKLLLAGGTSGITSWLSTYPMDVVKSRLQAD-GLQGTPRYR 229 Query: 452 TVVGTMQEVIAEEGLMGLSRGIGPRVL-----HSACFAAI 556 +V M++ EG +RG+ +L ++A FA + Sbjct: 230 GIVDCMRQSYQAEGWQVFTRGLASTLLRAFPVNAATFATV 269 Score = 39.3 bits (90), Expect = 0.010 Identities = 36/142 (25%), Positives = 63/142 (44%), Gaps = 8/142 (5%) Frame = +2 Query: 116 PKELITQRLQSGAATGRSWQVLLQ----ILQTDGFFGLYAGYAATLLRNLPAGVLSYS-S 280 P +++ RLQ + ++ L I++ + GLY G + L+ L + Sbjct: 21 PFDIVKVRLQVQSTEKPQYRGTLHCFQSIIKQESVLGLYKGLGSPLMGLTFINALVFGVQ 80 Query: 281 FEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVV 460 L+A +P L GA AGAI + P+++ KTRL + +RT Sbjct: 81 GNTLRALGQD-------SPLNQFLAGAAAGAIQCVICCPMELAKTRLQLQ-AVGPARTYK 132 Query: 461 GTMQ---EVIAEEGLMGLSRGI 517 G++ ++ EGL G++RG+ Sbjct: 133 GSLDCLVQIYRHEGLRGINRGM 154 Score = 31.6 bits (70), Expect = 2.1 Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 1/58 (1%) Frame = +2 Query: 350 LCGALAGAISAGLTTPLDVVKTRLMTRVGAQGS-RTVVGTMQEVIAEEGLMGLSRGIG 520 L G G + P D+VK RL + + R + Q +I +E ++GL +G+G Sbjct: 6 LAGCAGGVAGVIVGHPFDIVKVRLQVQSTEKPQYRGTLHCFQSIIKQESVLGLYKGLG 63
>UCP1_HUMAN (P25874) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 307 Score = 50.8 bits (120), Expect = 3e-06 Identities = 35/122 (28%), Positives = 58/122 (47%), Gaps = 5/122 (4%) Frame = +2 Query: 188 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAF-ALSKSNAPNLTPGESVLCGAL 364 +++T+G LY+G A L R + + L ++ ++ F K AP+L G +L G Sbjct: 65 VVKTEGRMKLYSGLPAGLQRQISSASLRIGLYDTVQEFLTAGKETAPSL--GSKILAGLT 122 Query: 365 AGAISAGLTTPLDVVKTRLMTRVGAQGSR-TVVGTMQE---VIAEEGLMGLSRGIGPRVL 532 G ++ + P +VVK RL + G + GT + EGL GL +G P ++ Sbjct: 123 TGGVAVFIGQPTEVVKVRLQAQSHLHGIKPRYTGTYNAYRIIATTEGLTGLWKGTTPNLM 182 Query: 533 HS 538 S Sbjct: 183 RS 184 Score = 45.8 bits (107), Expect = 1e-04 Identities = 40/170 (23%), Positives = 74/170 (43%), Gaps = 8/170 (4%) Frame = +2 Query: 116 PKELITQRLQSGAA--------TGRSWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLS 271 P E++ RLQ+ + TG ++ I T+G GL+ G L+R++ Sbjct: 133 PTEVVKVRLQAQSHLHGIKPRYTG-TYNAYRIIATTEGLTGLWKGTTPNLMRSVIINCTE 191 Query: 272 YSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSR 451 +++ +K + + + P V +AG + +++P+DVVKTR + Q + Sbjct: 192 LVTYDLMKEAFVKNNILADDVPCHLV-SALIAGFCATAMSSPVDVVKTRFINSPPGQ-YK 249 Query: 452 TVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMILKS 601 +V +V EG +G+ P L + I + FE + + KS Sbjct: 250 SVPNCAMKVFTNEGPTAFFKGLVPSFLRLGSWNVIMFVCFEQLKRELSKS 299
>PM34_HUMAN (O43808) Peroxisomal membrane protein PMP34 (34 kDa peroxisomal| membrane protein) (Solute carrier family 25 member 17) Length = 307 Score = 50.8 bits (120), Expect = 3e-06 Identities = 38/153 (24%), Positives = 73/153 (47%), Gaps = 8/153 (5%) Frame = +2 Query: 176 VLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLC 355 VLL+I++ +G Y G+ + + + + +F LKA + ++ T G+ ++ Sbjct: 51 VLLEIIKEEGLLAPYRGWFPVISSLCCSNFVYFYTFNSLKALWVKGQHS---TTGKDLVV 107 Query: 356 GALAGAISAGLTTPLDVVKTRLMTR--------VGAQGSRTVVGTMQEVIAEEGLMGLSR 511 G +AG ++ LTTPL VV TRL + + + ++ ++I +EG+ L Sbjct: 108 GFVAGVVNVLLTTPLWVVNTRLKLQGAKFRNEDIVPTNYKGIIDAFHQIIRDEGISALWN 167 Query: 512 GIGPRVLHSACFAAIGYCAFETARLMILKSYLE 610 G P +L AI + +E + +LK ++ Sbjct: 168 GTFPSLL-LVFNPAIQFMFYEGLKRQLLKKRMK 199 Score = 32.0 bits (71), Expect = 1.6 Identities = 21/83 (25%), Positives = 38/83 (45%) Frame = +2 Query: 350 LCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRV 529 + GA+ + + PLD + RL + S+T + E+I EEGL+ RG P + Sbjct: 14 VAGAVGSVTAMTVFFPLDTARLRLQVDEKRK-SKTTHMVLLEIIKEEGLLAPYRGWFPVI 72 Query: 530 LHSACFAAIGYCAFETARLMILK 598 C + + F + + + +K Sbjct: 73 SSLCCSNFVYFYTFNSLKALWVK 95
>ADT_DROME (Q26365) ADP,ATP carrier protein (ADP/ATP translocase) (Adenine| nucleotide translocator) (ANT) (Stress sensitive B protein) Length = 312 Score = 50.1 bits (118), Expect = 6e-06 Identities = 38/143 (26%), Positives = 65/143 (45%), Gaps = 6/143 (4%) Frame = +2 Query: 182 LQILQTDGFFGLYAGYAATLLRNLPAGVLSYS-SFEYLKAF--ALSKSNAPNLTPGESVL 352 ++I + GF + G A ++R P L+++ +Y + F + K+ ++ Sbjct: 74 IRIPKEQGFSSFWRGNLANVIRYFPTQALNFAFKDKYKQVFLGGVDKNTQFWRYFAGNLA 133 Query: 353 CGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVG---TMQEVIAEEGLMGLSRGIGP 523 G AGA S PLD +TRL G G R G + ++ +G++GL RG G Sbjct: 134 SGGAAGATSLCFVYPLDFARTRLAADTGKGGQREFTGLGNCLTKIFKSDGIVGLYRGFGV 193 Query: 524 RVLHSACFAAIGYCAFETARLMI 592 V + A + ++TAR M+ Sbjct: 194 SVQGIIIYRAAYFGFYDTARGML 216 Score = 32.0 bits (71), Expect = 1.6 Identities = 27/118 (22%), Positives = 54/118 (45%), Gaps = 11/118 (9%) Frame = +2 Query: 137 RLQSGAATGRSWQ--------VLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYL 292 R + A TG+ Q L +I ++DG GLY G+ ++ G++ Y + Y Sbjct: 153 RTRLAADTGKGGQREFTGLGNCLTKIFKSDGIVGLYRGFGVSV-----QGIIIYRA-AYF 206 Query: 293 KAFALSKSNAPNLTPGESVLCGALAGAIS--AGLTT-PLDVVKTRLMTRVGAQGSRTV 457 + ++ P+ + A+A ++ AG+ + P D V+ R+M + G + + + Sbjct: 207 GFYDTARGMLPDPKNTPIYISWAIAQVVTTVAGIVSYPFDTVRRRMMMQSGRKATEVI 264
>UCP3_CANFA (Q9N2I9) Mitochondrial uncoupling protein 3 (UCP 3)| Length = 311 Score = 50.1 bits (118), Expect = 6e-06 Identities = 39/149 (26%), Positives = 68/149 (45%), Gaps = 6/149 (4%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSK-SNAPNLTPGESVLC 355 +L +++T+G Y G A L R + + ++ +K F K S+ ++T +L Sbjct: 65 ILTMVRTEGPRSPYNGLVAGLQRQMSFASIRIGLYDSVKQFYTPKGSDHSSITT--RILA 122 Query: 356 GALAGAISAGLTTPLDVVKTRLMTRV--GAQGSRTVVGTM---QEVIAEEGLMGLSRGIG 520 G GA++ P DVVK R + GA +R GTM + + EEG+ GL +G Sbjct: 123 GCTTGAMAVSCAQPTDVVKVRFQASIHLGAGSNRKYSGTMDAYRTIAREEGVRGLWKGTL 182 Query: 521 PRVLHSACFAAIGYCAFETARLMILKSYL 607 P + +A ++ + +L +L Sbjct: 183 PNITRNAIVNCAEMVTYDIIKEKLLDYHL 211 Score = 38.9 bits (89), Expect = 0.013 Identities = 35/169 (20%), Positives = 70/169 (41%), Gaps = 8/169 (4%) Frame = +2 Query: 116 PKELITQRLQS----GAATGRSWQVLLQILQT----DGFFGLYAGYAATLLRNLPAGVLS 271 P +++ R Q+ GA + R + + +T +G GL+ G + RN Sbjct: 136 PTDVVKVRFQASIHLGAGSNRKYSGTMDAYRTIAREEGVRGLWKGTLPNITRNAIVNCAE 195 Query: 272 YSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSR 451 +++ +K L + P + AG + + +P+DVVKTR M Q Sbjct: 196 MVTYDIIKEKLLDYHLLTDNFPCHLISAFG-AGFCATVVASPVDVVKTRYMNSPPGQYC- 253 Query: 452 TVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMILK 598 + + M +++ +EG +G P L + + + +E + ++K Sbjct: 254 SPLDCMLKMVTQEGPTAFYKGFTPSFLRLGTWNVVMFVTYEQLKRALMK 302
>GHC1_MOUSE (Q9D6M3) Mitochondrial glutamate carrier 1 (GC-1) (Glutamate/H(+)| symporter 1) (Solute carrier family 25 member 22) Length = 323 Score = 50.1 bits (118), Expect = 6e-06 Identities = 31/86 (36%), Positives = 47/86 (54%), Gaps = 1/86 (1%) Frame = +2 Query: 173 QVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTP-GESV 349 Q+ +L+ G GLY G ATLLR++P ++ + F L L + ++ +P S Sbjct: 172 QLTRDLLRNHGIAGLYKGLGATLLRDVPFSIVYFPLFANLN--QLGRPSSEEKSPFYVSF 229 Query: 350 LCGALAGAISAGLTTPLDVVKTRLMT 427 L G +AG+ +A P DVVKTRL + Sbjct: 230 LAGCVAGSAAAVAVNPCDVVKTRLQS 255 Score = 47.8 bits (112), Expect = 3e-05 Identities = 41/183 (22%), Positives = 80/183 (43%), Gaps = 31/183 (16%) Frame = +2 Query: 116 PKELITQRLQSGAATGRSW----QVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSF 283 P +L RLQ+ R + L++ ++++G+FG+Y G A L P + ++ Sbjct: 28 PIDLAKTRLQNQQNGQRMYASMSDCLIKTIRSEGYFGMYRGAAVNLTLVTPEKAIKLAAN 87 Query: 284 EYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRL-------------- 421 ++ + LSK + LT + +L G AG +TTP++++K +L Sbjct: 88 DFFR-HQLSK-DGQKLTLPKEMLAGCGAGTCQVIVTTPMEMLKIQLQDAGRIAAQRKILA 145 Query: 422 -MTRVGAQGSR------------TVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGY 562 ++ AQG T ++++ G+ GL +G+G +L F+ + + Sbjct: 146 AQAQLSAQGGAQPSVEAPAPPRPTATQLTRDLLRNHGIAGLYKGLGATLLRDVPFSIVYF 205 Query: 563 CAF 571 F Sbjct: 206 PLF 208 Score = 30.4 bits (67), Expect = 4.7 Identities = 17/54 (31%), Positives = 26/54 (48%), Gaps = 1/54 (1%) Frame = +2 Query: 356 GALAGAISAGLTTPLDVVKTRLMTRVGAQGS-RTVVGTMQEVIAEEGLMGLSRG 514 G +AG I P+D+ KTRL + Q ++ + + I EG G+ RG Sbjct: 15 GGIAGLIGVTCVFPIDLAKTRLQNQQNGQRMYASMSDCLIKTIRSEGYFGMYRG 68
>PM34_MOUSE (O70579) Peroxisomal membrane protein PMP34 (34 kDa peroxisomal| membrane protein) (Solute carrier family 25 member 17) Length = 307 Score = 49.7 bits (117), Expect = 7e-06 Identities = 39/154 (25%), Positives = 75/154 (48%), Gaps = 9/154 (5%) Frame = +2 Query: 176 VLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLC 355 VLL+I++ +G Y G+ + + + + +F LKA + + + G+ ++ Sbjct: 51 VLLEIIKEEGLLAPYRGWFPVISSLCCSNFVYFYTFNSLKAVWVKGQRS---STGKDLVV 107 Query: 356 GALAGAISAGLTTPLDVVKTRLMTRVGAQ---------GSRTVVGTMQEVIAEEGLMGLS 508 G +AG ++ LTTPL VV TRL + GA+ + ++ ++I +EG++ L Sbjct: 108 GFVAGVVNVLLTTPLWVVNTRLKLQ-GAKFRNEDIIPTNYKGIIDAFHQIIRDEGILALW 166 Query: 509 RGIGPRVLHSACFAAIGYCAFETARLMILKSYLE 610 G P +L AI + +E + +LK ++ Sbjct: 167 NGTFPSLL-LVFNPAIQFMFYEGLKRQLLKKRMK 199 Score = 33.1 bits (74), Expect = 0.72 Identities = 22/88 (25%), Positives = 39/88 (44%) Frame = +2 Query: 350 LCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRV 529 + GA+ + + PLD + RL + S+T + E+I EEGL+ RG P + Sbjct: 14 VAGAVGSVTAMTVFFPLDTARLRLQVDEKRK-SKTTHAVLLEIIKEEGLLAPYRGWFPVI 72 Query: 530 LHSACFAAIGYCAFETARLMILKSYLES 613 C + + F + + + +K S Sbjct: 73 SSLCCSNFVYFYTFNSLKAVWVKGQRSS 100
>MFTC_MOUSE (Q8BMG8) Mitochondrial folate transporter/carrier (Solute carrier| family 25 member 32) Length = 316 Score = 49.7 bits (117), Expect = 7e-06 Identities = 40/142 (28%), Positives = 67/142 (47%), Gaps = 6/142 (4%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 358 L I + DG GLY G + + L + + +K++ ++ A L P E ++ Sbjct: 69 LATIWKVDGLRGLYQGVTPNVWGAGLSWGLYFFFYNAIKSYK-TEGRAEQLEPLEYLVSA 127 Query: 359 ALAGAISAGLTTPLDVVKTRLMTRVGAQGS------RTVVGTMQEVIAEEGLMGLSRGIG 520 A AGA++ +T PL V KTRLM + G S + + + ++ EG+ GL +G Sbjct: 128 AEAGAMTLCITNPLWVTKTRLMLQYGGVASPSQRQYKGMFDALVKIYKYEGVRGLYKGFV 187 Query: 521 PRVLHSACFAAIGYCAFETARL 586 P L A+ + A+E +L Sbjct: 188 PG-LFGTSHGALQFMAYELLKL 208 Score = 43.9 bits (102), Expect = 4e-04 Identities = 35/138 (25%), Positives = 62/138 (44%), Gaps = 3/138 (2%) Frame = +2 Query: 170 WQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFA---LSKSNAPNLTPG 340 + L++I + +G GLY G+ L G L + ++E LK +++ L+ Sbjct: 167 FDALVKIYKYEGVRGLYKGFVPGLF-GTSHGALQFMAYELLKLKYNKHINRLPEAQLSTA 225 Query: 341 ESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIG 520 E + AL+ + T P VV+ RL + + G T V T + +EG+ G +GI Sbjct: 226 EYISVAALSKIFAVAATYPYQVVRARLQDQHVSYGGVTDVIT--KTWRKEGIGGFYKGIA 283 Query: 521 PRVLHSACFAAIGYCAFE 574 P ++ I + +E Sbjct: 284 PNLIRVTPACCITFVVYE 301
>DIC_MOUSE (Q9QZD8) Mitochondrial dicarboxylate carrier (Solute carrier family| 25 member 10) Length = 287 Score = 49.7 bits (117), Expect = 7e-06 Identities = 40/168 (23%), Positives = 72/168 (42%), Gaps = 6/168 (3%) Frame = +2 Query: 116 PKELITQRLQSGAATG-RSWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYL 292 P +L+ LQ+ R + LQ+++TDGF LY G +A+L R + + ++ +E + Sbjct: 25 PLDLLKVHLQTQQEVKLRMTGMALQVVRTDGFLALYNGLSASLCRQMTYSLTRFAIYETM 84 Query: 293 KAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRT-----V 457 + + S P L VL G ++G + TP D+V R+ + S+ Sbjct: 85 RDYMTKDSQGP-LPFYNKVLLGGISGLTGGFVGTPADLVNVRMQNDMKLPPSQRRNYSHA 143 Query: 458 VGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMILKS 601 + + V EE L L G A ++ A+ ++L + Sbjct: 144 LDGLYRVAREESLRKLFSGATMASSRGALVTVGQLSCYDQAKQLVLST 191
>UCP1_CANFA (Q9GMZ1) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 309 Score = 49.3 bits (116), Expect = 1e-05 Identities = 42/169 (24%), Positives = 76/169 (44%), Gaps = 7/169 (4%) Frame = +2 Query: 116 PKELITQRLQSGAAT-GR------SWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSY 274 P E++ RLQ+ + GR ++ I T+G GL+ G L+RN+ Sbjct: 135 PTEVVKVRLQAQSHLHGRKPRYTGTYNAYRIIATTEGLTGLWKGTTPNLMRNVIINCTEL 194 Query: 275 SSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRT 454 +++ +K + + P L +AG + L++P+DVVKTR + V Q + + Sbjct: 195 VTYDLMKEALVKNHLLADDLPCH-FLSALVAGFCTTVLSSPVDVVKTRFVNSVPEQYT-S 252 Query: 455 VVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMILKS 601 V ++ +EG + +G P L + I + FE + ++KS Sbjct: 253 VPNCAMTMLTKEGPLAFFKGFVPSFLRLGSWNVIMFVCFEQLKRELMKS 301 Score = 35.8 bits (81), Expect = 0.11 Identities = 31/99 (31%), Positives = 46/99 (46%), Gaps = 9/99 (9%) Frame = +2 Query: 314 SNAPNLTPGESVLCGALAGA--ISAGLTTPLDVVKTRLMTRVGAQGS-------RTVVGT 466 S+AP P SV A AGA ++ +T PLD K RL + QG R V+GT Sbjct: 7 SDAP---PTLSVRIAAAAGAACLADMITFPLDTAKVRLQIQGEGQGQPPRAPRYRGVLGT 63 Query: 467 MQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETAR 583 + + EGL L G+ + FA++ +++ R Sbjct: 64 VATLARTEGLQKLYSGLPAGLQRQVGFASLRIGLYDSVR 102
>ODC_MOUSE (Q8BZ09) Mitochondrial 2-oxodicarboxylate carrier (Solute carrier| family 25 member 21) Length = 298 Score = 48.9 bits (115), Expect = 1e-05 Identities = 34/113 (30%), Positives = 56/113 (49%), Gaps = 3/113 (2%) Frame = +2 Query: 188 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 367 I +T+G FG Y G +L P + +S+FE K F S +P LT ++ G + Sbjct: 62 IFRTEGLFGFYKGIIPPILAETPKRAVKFSTFELYKKFLGYMSLSPGLT---FLIAGLGS 118 Query: 368 GAISAGLTTPLDVVKTRL-MTRVGAQGSRTVVGTMQEVIAEEGL--MGLSRGI 517 G A + P +VVK L + R + + +++I +EGL GL++G+ Sbjct: 119 GLTEAVVVNPFEVVKVGLQVNRNLFKEQPSTFAYARQIIKKEGLGFQGLNKGL 171 Score = 48.9 bits (115), Expect = 1e-05 Identities = 34/94 (36%), Positives = 43/94 (45%), Gaps = 4/94 (4%) Frame = +2 Query: 305 LSKSNAPNL-TPGESVLCGALAGAISAGLTTPLDVVKTRLMTR---VGAQGSRTVVGTMQ 472 +S SN L V G AG + L PLDVVKTR + Q RTV G+ Q Sbjct: 1 MSASNVSLLHETSRQVAAGGSAGLVEICLMHPLDVVKTRFQVQRSVTDPQSYRTVRGSFQ 60 Query: 473 EVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFE 574 + EGL G +GI P +L A+ + FE Sbjct: 61 MIFRTEGLFGFYKGIIPPILAETPKRAVKFSTFE 94 Score = 43.1 bits (100), Expect = 7e-04 Identities = 31/113 (27%), Positives = 53/113 (46%), Gaps = 3/113 (2%) Frame = +2 Query: 203 GFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISA 382 GF GL G ATL R+ ++ + + +K + S P L G ++G + + Sbjct: 163 GFQGLNKGLTATLGRHGIFNMVYFGFYHNVKNI-IPSSKDPTLEFLRKFGIGFVSGTMGS 221 Query: 383 GLTTPLDVVKTRLMTRVGAQGS---RTVVGTMQEVIAEEGLMGLSRGIGPRVL 532 P DV K+R+ G R+ TM+ + EEG++ L +G+ P+V+ Sbjct: 222 VFNIPFDVAKSRIQGPQPVPGEIKYRSCFKTMEMIYREEGILALYKGLVPKVM 274
>CRC1_YEAST (Q12289) Mitochondrial carnitine carrier| Length = 327 Score = 48.9 bits (115), Expect = 1e-05 Identities = 39/147 (26%), Positives = 65/147 (44%), Gaps = 6/147 (4%) Frame = +2 Query: 116 PKELITQRLQSGAATGRSWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLK 295 P E + LQ+ ++ G Q I++ G L+ G ATL R+ P L ++S+E K Sbjct: 161 PTERVKVVLQT-SSKGSFIQAAKTIVKEGGIASLFKGSLATLARDGPGSALYFASYEISK 219 Query: 296 AFALSKSNAPNLTPGESV------LCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTV 457 + S+ + E V L G +AG P+D +KT+L + + + Sbjct: 220 NYLNSRQPRQDAGKDEPVNILNVCLAGGIAGMSMWLAVFPIDTIKTKL--QASSTRQNML 277 Query: 458 VGTMQEVIAEEGLMGLSRGIGPRVLHS 538 T + + G+ G G+GP +L S Sbjct: 278 SATKEIYLQRGGIKGFFPGLGPALLRS 304
>M2OM_MOUSE (Q9CR62) Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP)| (Solute carrier family 25 member 11) Length = 313 Score = 48.5 bits (114), Expect = 2e-05 Identities = 49/176 (27%), Positives = 72/176 (40%), Gaps = 14/176 (7%) Frame = +2 Query: 116 PKELITQRLQ---SGAATGR---SWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYS 277 P +L+ R+Q GA T S+ L IL+T+G G+Y G +A LLR Sbjct: 40 PLDLVKNRMQLSGEGAKTREYKTSFHALTSILKTEGLKGIYTGLSAGLLRQATYTTTRLG 99 Query: 278 SFEYLKAFALSKSNAPNLTPG--ESVLCGALAGAISAGLTTPLDVVKTRLMTRVG----- 436 + L P PG L G AGA A + TP +V R MT G Sbjct: 100 IYTVLFERLTGADGTP---PGFLLKALIGMTAGATGAFVGTPAEVALIR-MTADGRLPAD 155 Query: 437 -AQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMILKS 601 +G + V + + EEG+ L RG P + + A ++ ++ +L S Sbjct: 156 QRRGYKNVFNALVRIAREEGVPTLWRGCIPTMARAVVVNAAQLASYSQSKQFLLDS 211 Score = 39.3 bits (90), Expect = 0.010 Identities = 31/125 (24%), Positives = 54/125 (43%), Gaps = 7/125 (5%) Frame = +2 Query: 170 WQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESV 349 + L++I + +G L+ G T+ R + +S+ K F L +++ Sbjct: 164 FNALVRIAREEGVPTLWRGCIPTMARAVVVNAAQLASYSQSKQFLLDSGYF-----SDNI 218 Query: 350 LCGALAGAISAGLTT----PLDVVKTRLMTRVGAQGS---RTVVGTMQEVIAEEGLMGLS 508 LC A IS +TT P+D+VKTR+ G + + + +V+ EG L Sbjct: 219 LCHFCASMISGLVTTAASMPVDIVKTRIQNMRMIDGKPEYKNGLDVLLKVVRYEGFFSLW 278 Query: 509 RGIGP 523 +G P Sbjct: 279 KGFTP 283 Score = 32.0 bits (71), Expect = 1.6 Identities = 20/71 (28%), Positives = 35/71 (49%), Gaps = 5/71 (7%) Frame = +2 Query: 350 LCGALAGAISAGLTTPLDVVKTRLMTRVGAQGS-----RTVVGTMQEVIAEEGLMGLSRG 514 L G LAG + PLD+VK R+ ++ +G+ +T + ++ EGL G+ G Sbjct: 25 LFGGLAGMGATVFVQPLDLVKNRM--QLSGEGAKTREYKTSFHALTSILKTEGLKGIYTG 82 Query: 515 IGPRVLHSACF 547 + +L A + Sbjct: 83 LSAGLLRQATY 93
>OAC1_YEAST (P32332) Mitochondrial oxaloacetate transport protein| (Mitochondrial carrier protein PMT) Length = 324 Score = 48.5 bits (114), Expect = 2e-05 Identities = 48/184 (26%), Positives = 88/184 (47%), Gaps = 20/184 (10%) Frame = +2 Query: 116 PKELITQRLQ----SGAATGRSWQVLLQ----ILQTDGFFGLYAGYAATLLRNLPAGVLS 271 P ELI R+Q A+ + ++ +Q I + +G GL G A + + Sbjct: 42 PIELIKIRMQLQGEMSASAAKVYKNPIQGMAVIFKNEGIKGLQKGLNAAYIYQIGLNGSR 101 Query: 272 YSSFEYLKAFALSKSNAPNLTP------GESVLCGALAGAISAGLTTPLDVVKTRLMT-- 427 +E +++ +L++ P+ P G +V GA +G I A + +PL +VKTRL + Sbjct: 102 LGFYEPIRS-SLNQLFFPDQEPHKVQSVGVNVFSGAASGIIGAVIGSPLFLVKTRLQSYS 160 Query: 428 ---RVGAQGSRT-VVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMIL 595 ++G Q T V + + EG+ GL RGI +L + +++ + TA+ +++ Sbjct: 161 EFIKIGEQTHYTGVWNGLVTIFKTEGVKGLFRGIDAAILRTGAGSSVQLPIYNTAKNILV 220 Query: 596 KSYL 607 K+ L Sbjct: 221 KNDL 224
>UCP4_HUMAN (O95847) Mitochondrial uncoupling protein 4 (UCP 4) (Solute carrier| family 25 member 27) Length = 323 Score = 48.5 bits (114), Expect = 2e-05 Identities = 41/178 (23%), Positives = 78/178 (43%), Gaps = 15/178 (8%) Frame = +2 Query: 122 ELITQRLQSGAATGRSWQVLLQ----ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEY 289 E RL GA ++ +++ I++ +GF L+ G + R++ ++E+ Sbjct: 52 EAALARLGDGARESAPYRGMVRTALGIIEEEGFLKLWQGVTPAIYRHVVYSGGRMVTYEH 111 Query: 290 LKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVG-- 463 L+ KS + +SV+ G +AG I L P D+VK ++ +G R + G Sbjct: 112 LREVVFGKSEDEHYPLWKSVIGGMMAGVIGQFLANPTDLVKVQMQ----MEGKRKLEGKP 167 Query: 464 --------TMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETAR-LMILKSYLE 610 +++AE G+ GL G P + +A ++T + ++L + LE Sbjct: 168 LRFRGVHHAFAKILAEGGIRGLWAGWVPNIQRAALVNMGDLTTYDTVKHYLVLNTPLE 225 Score = 45.4 bits (106), Expect = 1e-04 Identities = 35/142 (24%), Positives = 67/142 (47%), Gaps = 7/142 (4%) Frame = +2 Query: 185 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPN--LTPGESVLCG 358 +IL G GL+AG+ + R + ++++ +K + + + + +T G S LC Sbjct: 179 KILAEGGIRGLWAGWVPNIQRAALVNMGDLTTYDTVKHYLVLNTPLEDNIMTHGLSSLCS 238 Query: 359 ALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVV-----GTMQEVIAEEGLMGLSRGIGP 523 L +I L TP DV+K+R+M + + R ++ + + + EG M L +G P Sbjct: 239 GLVASI---LGTPADVIKSRIMNQPRDKQGRGLLYKSSTDCLIQAVQGEGFMSLYKGFLP 295 Query: 524 RVLHSACFAAIGYCAFETARLM 589 L ++ + + +E R M Sbjct: 296 SWLRMTPWSMVFWLTYEKIREM 317 Score = 31.6 bits (70), Expect = 2.1 Identities = 24/93 (25%), Positives = 41/93 (44%), Gaps = 12/93 (12%) Frame = +2 Query: 350 LCGALAGAISAGLTTPLDVVKTRL-------MTRVG-----AQGSRTVVGTMQEVIAEEG 493 L A ++ T PLD+ KTRL + R+G + R +V T +I EEG Sbjct: 24 LLSGCAATVAELATFPLDLTKTRLQMQGEAALARLGDGARESAPYRGMVRTALGIIEEEG 83 Query: 494 LMGLSRGIGPRVLHSACFAAIGYCAFETARLMI 592 + L +G+ P + ++ +E R ++ Sbjct: 84 FLKLWQGVTPAIYRHVVYSGGRMVTYEHLREVV 116 Score = 30.0 bits (66), Expect = 6.1 Identities = 13/43 (30%), Positives = 25/43 (58%) Frame = +2 Query: 167 SWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLK 295 S L+Q +Q +GF LY G+ + LR P ++ + ++E ++ Sbjct: 273 STDCLIQAVQGEGFMSLYKGFLPSWLRMTPWSMVFWLTYEKIR 315
>ODC2_YEAST (Q99297) Mitochondrial 2-oxodicarboxylate carrier 2| Length = 307 Score = 48.1 bits (113), Expect = 2e-05 Identities = 39/171 (22%), Positives = 71/171 (41%), Gaps = 16/171 (9%) Frame = +2 Query: 53 PFLVPPLXXXXXXXXXXXXMVPKELITQRLQ------SGAATGRSWQ-------VLLQIL 193 PF+ + M P +++ R Q + AA G+ + L +I+ Sbjct: 11 PFIYQFISGAVAGISELTVMYPLDVVKTRFQLEVTTPTAAAVGKQVERYNGVIDCLKKIV 70 Query: 194 QTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAGA 373 + +GF LY G ++ +L P ++ + + + N T S+ GA AG Sbjct: 71 KKEGFSRLYRGISSPMLMEAPKRATKFACNDQYQKIFKNLFNTNETTQKISIAAGASAGM 130 Query: 374 ISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTM---QEVIAEEGLMGLSRGI 517 A + P +++K R+ + +G M ++ I EG+MGL +GI Sbjct: 131 TEAAVIVPFELIKIRMQ-----DVKSSYLGPMDCLKKTIKNEGIMGLYKGI 176 Score = 47.4 bits (111), Expect = 4e-05 Identities = 41/151 (27%), Positives = 70/151 (46%), Gaps = 7/151 (4%) Frame = +2 Query: 110 MVPKELITQRLQSGAATGRS-WQVLLQILQTDGFFGLYAGYAATLLRN-LPAGVLSYSSF 283 +VP ELI R+Q ++ L + ++ +G GLY G +T+ RN L G + Sbjct: 136 IVPFELIKIRMQDVKSSYLGPMDCLKKTIKNEGIMGLYKGIESTMWRNALWNGGYFGVIY 195 Query: 284 EYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRT--- 454 + + ++K+ ++ GA+ G + L TP DVVK+R+ + V A S Sbjct: 196 QVRNSMPVAKTKGQKTR--NDLIAGAIGGTVGTMLNTPFDVVKSRIQS-VDAVSSAVKKY 252 Query: 455 --VVGTMQEVIAEEGLMGLSRGIGPRVLHSA 541 + ++ + EEG L +G P+V A Sbjct: 253 NWCLPSLLVIYREEGFRALYKGFVPKVCRLA 283 Score = 37.4 bits (85), Expect = 0.038 Identities = 30/88 (34%), Positives = 41/88 (46%), Gaps = 10/88 (11%) Frame = +2 Query: 308 SKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLM--------TRVGAQGSR--TV 457 S SNA L + GA+AG + PLDVVKTR VG Q R V Sbjct: 3 SDSNAKPLPFIYQFISGAVAGISELTVMYPLDVVKTRFQLEVTTPTAAAVGKQVERYNGV 62 Query: 458 VGTMQEVIAEEGLMGLSRGIGPRVLHSA 541 + +++++ +EG L RGI +L A Sbjct: 63 IDCLKKIVKKEGFSRLYRGISSPMLMEA 90
>PM47B_CANBO (Q00319) Peroxisomal membrane protein PMP47B| Length = 419 Score = 48.1 bits (113), Expect = 2e-05 Identities = 46/159 (28%), Positives = 67/159 (42%), Gaps = 16/159 (10%) Frame = +2 Query: 170 WQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPG--- 340 +++L +IL+ G GLY G + L + Y +E L LS+ + P T G Sbjct: 77 FEILKKILKDQGAKGLYNGLESALFGIAVTNFVYYYFYE-LTGKTLSRRSNPQTTSGSKK 135 Query: 341 ----------ESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVI--- 481 +S+ GA+AG IS T P+ V TR+ QG + T++ +I Sbjct: 136 VTLKKGLSVWQSMAAGAVAGTISRVATNPIWVANTRMTILSKNQGKLGKLNTIEAIIYIL 195 Query: 482 AEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMILK 598 EG L GI P L I Y FE + I+K Sbjct: 196 KNEGWQKLFTGIVP-ALFLVLNPIIQYTIFEQLKSFIVK 233
>YAD8_SCHPO (Q09834) Putative mitochondrial carrier C4G8.08| Length = 271 Score = 48.1 bits (113), Expect = 2e-05 Identities = 40/167 (23%), Positives = 70/167 (41%), Gaps = 13/167 (7%) Frame = +2 Query: 116 PKELITQRLQSGAATGRSWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLK 295 P E+I R Q + G + + +++G G Y GY + LP V + +E K Sbjct: 103 PLEVIKARTQI-SQKGSVINTISTLARSEGLKGFYRGYWMGVAIYLPTTVSWWVCYEESK 161 Query: 296 AFALSKSN--APNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTM 469 + +SN + P +C AL ++ ++TPLD+VKTR + + G Sbjct: 162 KYLQKQSNWDISVIAP----ICSALGTVVATTISTPLDIVKTRYQVATSSAMRKAEYGLQ 217 Query: 470 QE-----------VIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFET 577 E + ++ G+ G +RG+ R+ + I FE+ Sbjct: 218 AEKELGILEIAKLLFSKHGVKGFTRGLFTRMCYIMPSGMISMSVFES 264 Score = 40.4 bits (93), Expect = 0.005 Identities = 33/112 (29%), Positives = 55/112 (49%), Gaps = 5/112 (4%) Frame = +2 Query: 194 QTDGFFGLYAGYAATLLRNLPAGV--LSYSSFEYLKAFALSKSN-APNLTPGESV--LCG 358 QT G F R LP + ++ ++ YL + +K P++ G + +CG Sbjct: 31 QTIGKFSFKTMPLKAYYRGLPISLTLITPATCLYLSTYVEAKRRFKPSVGEGAILYSICG 90 Query: 359 ALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRG 514 A +S+ + TPL+V+K R T++ +GS V+ T+ + EGL G RG Sbjct: 91 MTAEVVSSFVWTPLEVIKAR--TQISQKGS--VINTISTLARSEGLKGFYRG 138
>YIA6_YEAST (P40556) Putative mitochondrial carrier YIL006W| Length = 373 Score = 48.1 bits (113), Expect = 2e-05 Identities = 33/91 (36%), Positives = 45/91 (49%), Gaps = 5/91 (5%) Frame = +2 Query: 275 SSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTR-----LMTRVGA 439 SS E + L K P + + L GA AG +S PLDV KTR L TR Sbjct: 57 SSTESIIGTTLRKKWVPLSSTQITALSGAFAGFLSGVAVCPLDVAKTRLQAQGLQTRFEN 116 Query: 440 QGSRTVVGTMQEVIAEEGLMGLSRGIGPRVL 532 R ++GT+ ++ +EG GL +G+ P VL Sbjct: 117 PYYRGIMGTLSTIVRDEGPRGLYKGLVPIVL 147 Score = 42.4 bits (98), Expect = 0.001 Identities = 35/122 (28%), Positives = 55/122 (45%), Gaps = 4/122 (3%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 358 L I++ +G GLY G +L P ++ +S +E+ K F P Sbjct: 126 LSTIVRDEGPRGLYKGLVPIVLGYFPTWMIYFSVYEFSKKFF--HGIFPQFDFVAQSCAA 183 Query: 359 ALAGAISAGLTTPLDVVKTRLM--TRVGAQGS--RTVVGTMQEVIAEEGLMGLSRGIGPR 526 AGA S LT P+ VVKTRLM + +G + + +++ +EG L G+ P Sbjct: 184 ITAGAASTTLTNPIWVVKTRLMLQSNLGEHPTHYKGTFDAFRKLFYQEGFKALYAGLVPS 243 Query: 527 VL 532 +L Sbjct: 244 LL 245 Score = 38.5 bits (88), Expect = 0.017 Identities = 33/138 (23%), Positives = 65/138 (47%), Gaps = 5/138 (3%) Frame = +2 Query: 185 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKA--FALSKSNAPN-LTPGESVLC 355 ++ +GF LYAG +LL L + + +E LK S+ N N + ++ Sbjct: 226 KLFYQEGFKALYAGLVPSLL-GLFHVAIHFPIYEDLKVRFHCYSRENNTNSINLQRLIMA 284 Query: 356 GALAGAISAGLTTPLDVVKTRLMTRVGAQGS--RTVVGTMQEVIAEEGLMGLSRGIGPRV 529 +++ I++ +T P ++++TR+ + S R + ++ A+EGL G G + Sbjct: 285 SSVSKMIASAVTYPHEILRTRMQLKSDIPDSIQRRLFPLIKATYAQEGLKGFYSGFTTNL 344 Query: 530 LHSACFAAIGYCAFETAR 583 + + +AI +FE R Sbjct: 345 VRTIPASAITLVSFEYFR 362 Score = 34.7 bits (78), Expect = 0.25 Identities = 17/65 (26%), Positives = 32/65 (49%), Gaps = 5/65 (7%) Frame = +2 Query: 116 PKELITQRLQ-----SGAATGRSWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSS 280 P E++ R+Q + R + ++ +G G Y+G+ L+R +PA ++ S Sbjct: 298 PHEILRTRMQLKSDIPDSIQRRLFPLIKATYAQEGLKGFYSGFTTNLVRTIPASAITLVS 357 Query: 281 FEYLK 295 FEY + Sbjct: 358 FEYFR 362
>M2OM_BOVIN (P22292) Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP)| (Solute carrier family 25 member 11) Length = 313 Score = 47.8 bits (112), Expect = 3e-05 Identities = 47/176 (26%), Positives = 73/176 (41%), Gaps = 14/176 (7%) Frame = +2 Query: 116 PKELITQRLQ---SGAATGR---SWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYS 277 P +L+ R+Q GA T S+ L+ IL+ +G G+Y G +A LLR Sbjct: 40 PLDLVKNRMQLSGEGAKTREYKTSFHALISILRAEGLRGIYTGLSAGLLRQATYTTTRLG 99 Query: 278 SFEYLKAFALSKSNAPNLTPG--ESVLCGALAGAISAGLTTPLDVVKTRLMTRVG----- 436 + L P PG + G AGA A + TP +V R MT G Sbjct: 100 IYTVLFERLTGADGTP---PGFLLKAVIGMTAGATGAFVGTPAEVALIR-MTADGRLPVD 155 Query: 437 -AQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMILKS 601 +G + V + ++ EEG+ L RG P + + A ++ ++ +L S Sbjct: 156 QRRGYKNVFNALFRIVQEEGVPTLWRGCIPTMARAVVVNAAQLASYSQSKQFLLDS 211 Score = 41.2 bits (95), Expect = 0.003 Identities = 32/125 (25%), Positives = 54/125 (43%), Gaps = 7/125 (5%) Frame = +2 Query: 170 WQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESV 349 + L +I+Q +G L+ G T+ R + +S+ K F L +++ Sbjct: 164 FNALFRIVQEEGVPTLWRGCIPTMARAVVVNAAQLASYSQSKQFLLDSGYF-----SDNI 218 Query: 350 LCGALAGAISAGLTT----PLDVVKTRLMTRVGAQGS---RTVVGTMQEVIAEEGLMGLS 508 LC A IS +TT P+D+VKTR+ G + + + +V+ EG L Sbjct: 219 LCHFCASMISGLVTTAASMPVDIVKTRIQNMRMIDGKPEYKNGLDVLVKVVRYEGFFSLW 278 Query: 509 RGIGP 523 +G P Sbjct: 279 KGFTP 283 Score = 31.2 bits (69), Expect = 2.7 Identities = 20/71 (28%), Positives = 35/71 (49%), Gaps = 5/71 (7%) Frame = +2 Query: 350 LCGALAGAISAGLTTPLDVVKTRLMTRVGAQGS-----RTVVGTMQEVIAEEGLMGLSRG 514 L G LAG + PLD+VK R+ ++ +G+ +T + ++ EGL G+ G Sbjct: 25 LFGGLAGMGATVFVQPLDLVKNRM--QLSGEGAKTREYKTSFHALISILRAEGLRGIYTG 82 Query: 515 IGPRVLHSACF 547 + +L A + Sbjct: 83 LSAGLLRQATY 93
>FLX1_YEAST (P40464) Mitochondrial FAD carrier protein FLX1| Length = 311 Score = 47.8 bits (112), Expect = 3e-05 Identities = 48/191 (25%), Positives = 85/191 (44%), Gaps = 25/191 (13%) Frame = +2 Query: 116 PKELITQRLQSGAATGRS-----WQVLLQILQTDGFFG------LYAGYAATLLRNLPAG 262 P +L+ RLQ A + + + V+ +I+++ G LY G + L N A Sbjct: 29 PLDLLKVRLQLSATSAQKAHYGPFMVIKEIIRSSANSGRSVTNELYRGLSINLFGNAIAW 88 Query: 263 VLSYSSFEYLKAFALSKSNAPNLTPGESV------------LCGALAGAISAGLTTPLDV 406 + + + K P T + V GA +G ++A LT P+ V Sbjct: 89 GVYFGLYGVTKELIYKSVAKPGETQLKGVGNDHKMNSLIYLSAGASSGLMTAILTNPIWV 148 Query: 407 VKTRLM-TRVGAQGSRT-VVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETA 580 +KTR+M T GAQG+ T + +Q+++ +G GL +G+ P L A+ + ++T Sbjct: 149 IKTRIMSTSKGAQGAYTSMYNGVQQLLRTDGFQGLWKGLVP-ALFGVSQGALYFAVYDTL 207 Query: 581 RLMILKSYLES 613 + L+ E+ Sbjct: 208 KQRKLRRKREN 218 Score = 39.7 bits (91), Expect = 0.008 Identities = 21/63 (33%), Positives = 37/63 (58%), Gaps = 3/63 (4%) Frame = +2 Query: 116 PKELITQRLQSGAATGRSWQV---LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFE 286 P +L+ LQS A + +++ + I+ DGF GLY G +A L+R +P+ +++ +E Sbjct: 246 PFQLLKSNLQSFRANEQKFRLFPLIKLIIANDGFVGLYKGLSANLVRAIPSTCITFCVYE 305 Query: 287 YLK 295 LK Sbjct: 306 NLK 308
>MCATL_HUMAN (Q8N8R3) Mitchondrial carnitine/acylcarnitine carrier protein CACL| (CACT-like) (Solute carrier family 25 member 29) Length = 303 Score = 47.8 bits (112), Expect = 3e-05 Identities = 46/159 (28%), Positives = 74/159 (46%), Gaps = 12/159 (7%) Frame = +2 Query: 116 PKELITQRLQ-SGAATGRSWQ----VLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSS 280 P EL RLQ A R+++ L QI +G G+ G +TLLR P+ + + + Sbjct: 112 PMELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLT 171 Query: 281 FEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMT--RVGAQGSRT 454 ++ L AL L + +L G +G +S T P+DVVK+RL GA R Sbjct: 172 YDALTR-ALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQADGLRGAPRYRG 230 Query: 455 VVGTMQEVIAEEGLMGLSRGIGPRVL-----HSACFAAI 556 ++ + + EG +RG+ +L ++A FA + Sbjct: 231 ILDCVHQSYRAEGWRVFTRGLASTLLRAFPVNAATFATV 269 Score = 39.3 bits (90), Expect = 0.010 Identities = 23/65 (35%), Positives = 37/65 (56%), Gaps = 3/65 (4%) Frame = +2 Query: 332 TPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQ---EVIAEEGLMG 502 +P L GA AGAI + P+++ KTRL + A +RT G++ ++ EGL G Sbjct: 91 SPLNQFLAGAAAGAIQCVICCPMELAKTRLQLQ-DAGPARTYKGSLDCLAQIYGHEGLRG 149 Query: 503 LSRGI 517 ++RG+ Sbjct: 150 VNRGM 154 Score = 29.6 bits (65), Expect = 8.0 Identities = 17/58 (29%), Positives = 27/58 (46%), Gaps = 1/58 (1%) Frame = +2 Query: 350 LCGALAGAISAGLTTPLDVVKTRLMTR-VGAQGSRTVVGTMQEVIAEEGLMGLSRGIG 520 L G G + P D VK RL + V R + + +I +E ++GL +G+G Sbjct: 6 LAGCAGGVAGVLVGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLYKGLG 63
>ADT3_YEAST (P18238) ADP,ATP carrier protein 3 (ADP/ATP translocase 3) (Adenine| nucleotide translocator 3) (ANT 3) Length = 307 Score = 47.8 bits (112), Expect = 3e-05 Identities = 35/131 (26%), Positives = 62/131 (47%), Gaps = 4/131 (3%) Frame = +2 Query: 176 VLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLC 355 V + L++DG GLY G+ +++ + L + F+ LK L+ S G + Sbjct: 165 VYKKTLKSDGIAGLYRGFMPSVVGIVVYRGLYFGMFDSLKPLVLTGS-----LDGSFLAS 219 Query: 356 GALAGAISAGLTT---PLDVVKTRLMTRVG-AQGSRTVVGTMQEVIAEEGLMGLSRGIGP 523 L ++ G +T PLD V+ R+M G A + +++++A EG+ L +G G Sbjct: 220 FLLGWVVTTGASTCSYPLDTVRRRMMMTSGQAVKYNGAIDCLKKIVASEGVGSLFKGCGA 279 Query: 524 RVLHSACFAAI 556 +L S A + Sbjct: 280 NILRSVAGAGV 290 Score = 44.7 bits (104), Expect = 2e-04 Identities = 31/144 (21%), Positives = 62/144 (43%), Gaps = 7/144 (4%) Frame = +2 Query: 200 DGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKA-FALSKSNAPNLTPGESVLCGALAGAI 376 +G + G A ++R P L+++ + +K F K ++ G AGA+ Sbjct: 70 EGLISFWRGNTANVIRYFPTQALNFAFKDKIKLMFGFKKEEGYGKWFAGNLASGGAAGAL 129 Query: 377 SAGLTTPLDVVKTRLMT------RVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHS 538 S LD +TRL + GA+ + ++ + +G+ GL RG P V+ Sbjct: 130 SLLFVYSLDFARTRLAADAKSSKKGGARQFNGLTDVYKKTLKSDGIAGLYRGFMPSVVGI 189 Query: 539 ACFAAIGYCAFETARLMILKSYLE 610 + + + F++ + ++L L+ Sbjct: 190 VVYRGLYFGMFDSLKPLVLTGSLD 213
>ODC_HUMAN (Q9BQT8) Mitochondrial 2-oxodicarboxylate carrier (Solute carrier| family 25 member 21) Length = 299 Score = 47.4 bits (111), Expect = 4e-05 Identities = 46/176 (26%), Positives = 77/176 (43%), Gaps = 15/176 (8%) Frame = +2 Query: 110 MVPKELITQR--LQSGAATGRSWQVLLQ----ILQTDGFFGLYAGYAATLLRNLPAGVLS 271 M P +++ R +Q A S++ L+ I Q +G FG Y G +L P + Sbjct: 31 MHPLDVVKTRFQIQRCATDPNSYKSLVDSFRMIFQMEGLFGFYKGILPPILAETPKRAVK 90 Query: 272 YSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSR 451 + +FE K S +P LT + G +G A + P +VVK VG Q +R Sbjct: 91 FFTFEQYKKLLGYVSLSPALT---FAIAGLGSGLTEAIVVNPFEVVK------VGLQANR 141 Query: 452 -------TVVGTMQEVIAEE--GLMGLSRGIGPRVLHSACFAAIGYCAFETARLMI 592 + VG +++I +E GL GL++G+ + F + + + + MI Sbjct: 142 NTFAEQPSTVGYARQIIKKEGWGLQGLNKGLTATLGRHGVFNMVYFGFYYNVKNMI 197 Score = 45.8 bits (107), Expect = 1e-04 Identities = 40/137 (29%), Positives = 63/137 (45%), Gaps = 7/137 (5%) Frame = +2 Query: 185 QILQTDGFF--GLYAGYAATLLRNLPAGVLS--YSSFEYLKAFALSKSNAPNLTPGESVL 352 QI++ +G+ GL G ATL R+ GV + Y F Y + + P L Sbjct: 156 QIIKKEGWGLQGLNKGLTATLGRH---GVFNMVYFGFYYNVKNMIPVNKDPILEFWRKFG 212 Query: 353 CGALAGAISAGLTTPLDVVKTRLMTRVGAQGS---RTVVGTMQEVIAEEGLMGLSRGIGP 523 G L+G I++ + P DV K+R+ G RT TM V EEG++ L +G+ P Sbjct: 213 IGLLSGTIASVINIPFDVAKSRIQGPQPVPGEIKYRTCFKTMATVYQEEGILALYKGLLP 272 Query: 524 RVLHSACFAAIGYCAFE 574 +++ A+ +E Sbjct: 273 KIMRLGPGGAVMLLVYE 289 Score = 40.8 bits (94), Expect = 0.003 Identities = 24/85 (28%), Positives = 41/85 (48%), Gaps = 3/85 (3%) Frame = +2 Query: 347 VLCGALAGAISAGLTTPLDVVKTRLMTR---VGAQGSRTVVGTMQEVIAEEGLMGLSRGI 517 ++ G AG + L PLDVVKTR + +++V + + + EGL G +GI Sbjct: 17 IVAGGSAGLVEICLMHPLDVVKTRFQIQRCATDPNSYKSLVDSFRMIFQMEGLFGFYKGI 76 Query: 518 GPRVLHSACFAAIGYCAFETARLMI 592 P +L A+ + FE + ++ Sbjct: 77 LPPILAETPKRAVKFFTFEQYKKLL 101
>ODC1_YEAST (Q03028) Mitochondrial 2-oxodicarboxylate carrier 1| Length = 310 Score = 47.4 bits (111), Expect = 4e-05 Identities = 31/115 (26%), Positives = 58/115 (50%), Gaps = 2/115 (1%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPN--LTPGESVL 352 L +I++ +GF LY G + +L P + +S + + F PN +T ++ Sbjct: 68 LTKIVKKEGFSHLYKGITSPILMEAPKRAIKFSGNDTFQTFYKKIFPTPNGEMTQKIAIY 127 Query: 353 CGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGI 517 GA AGA+ A + P ++VK RL V +Q +T + ++ + + G++ L G+ Sbjct: 128 SGASAGAVEAFVVAPFELVKIRLQD-VNSQ-FKTPIEVVKNSVVKGGVLSLFNGL 180 Score = 43.1 bits (100), Expect = 7e-04 Identities = 39/148 (26%), Positives = 68/148 (45%), Gaps = 4/148 (2%) Frame = +2 Query: 110 MVPKELITQRLQSGAATGRS-WQVLLQILQTDGFFGLYAGYAATLLRNL--PAGVLSYSS 280 + P EL+ RLQ + ++ +V+ + G L+ G AT+ R++ AG Sbjct: 140 VAPFELVKIRLQDVNSQFKTPIEVVKNSVVKGGVLSLFNGLEATIWRHVLWNAGYFGII- 198 Query: 281 FEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVG-AQGSRTV 457 F+ K +K++ ++ GA+ G + L TP DVVK+R+ G + Sbjct: 199 FQIRKLLPAAKTSTEKTR--NDLIAGAIGGTVGCLLNTPFDVVKSRIQRSSGPLRKYNWS 256 Query: 458 VGTMQEVIAEEGLMGLSRGIGPRVLHSA 541 + ++ V EEG L +G P+V+ A Sbjct: 257 LPSVLLVYREEGFKALYKGFAPKVMRLA 284 Score = 37.4 bits (85), Expect = 0.038 Identities = 27/96 (28%), Positives = 43/96 (44%), Gaps = 13/96 (13%) Frame = +2 Query: 356 GALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGT-------------MQEVIAEEGL 496 GA+AG + PLDVVKTR+ +V +G VV + +++ +EG Sbjct: 18 GAIAGVSELLVMYPLDVVKTRMQLQVTTKGHPAVVAAKAAVDHYTGVMDCLTKIVKKEGF 77 Query: 497 MGLSRGIGPRVLHSACFAAIGYCAFETARLMILKSY 604 L +GI +L A AI + +T + K + Sbjct: 78 SHLYKGITSPILMEAPKRAIKFSGNDTFQTFYKKIF 113 Score = 30.0 bits (66), Expect = 6.1 Identities = 17/55 (30%), Positives = 30/55 (54%), Gaps = 4/55 (7%) Frame = +2 Query: 116 PKELITQRLQ--SGAATGRSWQV--LLQILQTDGFFGLYAGYAATLLRNLPAGVL 268 P +++ R+Q SG +W + +L + + +GF LY G+A ++R P G L Sbjct: 235 PFDVVKSRIQRSSGPLRKYNWSLPSVLLVYREEGFKALYKGFAPKVMRLAPGGGL 289
>ADT2_ANOGA (Q7PQV7) ADP,ATP carrier protein 2 (ADP/ATP translocase 2) (Adenine| nucleotide translocator 2) (ANT 2) Length = 300 Score = 47.0 bits (110), Expect = 5e-05 Identities = 38/144 (26%), Positives = 66/144 (45%), Gaps = 7/144 (4%) Frame = +2 Query: 182 LQILQTDGFFGLYAGYAATLLRNLPAGVLSYS-SFEYLKAFALSKSNAPNLTPG--ESVL 352 ++I + GF + G A ++R P L+++ +Y + F T ++ Sbjct: 61 VRIPREQGFSAFWRGNLANVIRYFPTQALNFAFKDKYKQVFLGGVDKNTQFTRYFIGNLA 120 Query: 353 CGALAGAISAGLTTPLDVVKTRLMTRVG----AQGSRTVVGTMQEVIAEEGLMGLSRGIG 520 G +AGA S PLD +TRL VG A+ + + + ++ +GL+GL RG G Sbjct: 121 SGGMAGATSLCFVYPLDFARTRLAADVGKGAEAREFKGLGDCISKIFKTDGLVGLYRGFG 180 Query: 521 PRVLHSACFAAIGYCAFETARLMI 592 V + A + ++TAR M+ Sbjct: 181 VSVQGIIIYRAAYFGFYDTARGML 204
>TXTP_HUMAN (P53007) Tricarboxylate transport protein, mitochondrial precursor| (Citrate transport protein) (CTP) (Tricarboxylate carrier protein) (Solute carrier family 25 member 1) Length = 311 Score = 47.0 bits (110), Expect = 5e-05 Identities = 35/130 (26%), Positives = 60/130 (46%) Frame = +2 Query: 185 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGAL 364 +I++ G G Y G AT+L+ + + L+ + + + P + + GA+ Sbjct: 170 EIVREQGLKGTYQGLTATVLKQGSNQAIRFFVMTSLRNWYRGDNPNKPMNPLITGVFGAI 229 Query: 365 AGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSAC 544 AGA S TPLDV+KTR M + A R +++ +EGL +G PR+ Sbjct: 230 AGAASVFGNTPLDVIKTR-MQGLEAHKYRNTWDCGLQILKKEGLKAFYKGTVPRLGRVCL 288 Query: 545 FAAIGYCAFE 574 AI + ++ Sbjct: 289 DVAIVFVIYD 298 Score = 45.8 bits (107), Expect = 1e-04 Identities = 33/136 (24%), Positives = 61/136 (44%), Gaps = 3/136 (2%) Frame = +2 Query: 185 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGAL 364 Q +++ G GLY G ++ L ++P + + FE+L + T G +LCG Sbjct: 73 QTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGMFEFLSNHMRDAQGRLDSTRG--LLCGLG 130 Query: 365 AGAISAGLTT-PLDVVKTRLMTRVGAQGS--RTVVGTMQEVIAEEGLMGLSRGIGPRVLH 535 AG A + P++ +K + + + R ++E++ E+GL G +G+ VL Sbjct: 131 AGVAEAVVVVCPMETIKVKFIHDQTSPNPKYRGFFHGVREIVREQGLKGTYQGLTATVLK 190 Query: 536 SACFAAIGYCAFETAR 583 AI + + R Sbjct: 191 QGSNQAIRFFVMTSLR 206 Score = 45.4 bits (106), Expect = 1e-04 Identities = 30/97 (30%), Positives = 48/97 (49%), Gaps = 2/97 (2%) Frame = +2 Query: 290 LKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLM--TRVGAQGSRTVVG 463 L A A + A PG+++L G LAG I +T P + VKT+L R R + Sbjct: 10 LAAAAPASGKAKLTHPGKAILAGGLAGGIEICITFPTEYVKTQLQLDERSHPPRYRGIGD 69 Query: 464 TMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFE 574 +++ + G++GL RG+ + S AA+ + FE Sbjct: 70 CVRQTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGMFE 106
>TXTP_BOVIN (P79110) Tricarboxylate transport protein, mitochondrial precursor| (Citrate transport protein) (CTP) (Tricarboxylate carrier protein) (Solute carrier family 25 member 1) Length = 311 Score = 47.0 bits (110), Expect = 5e-05 Identities = 35/130 (26%), Positives = 60/130 (46%) Frame = +2 Query: 185 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGAL 364 +I++ G G Y G AT+L+ + + L+ + + + P + + GA+ Sbjct: 170 EIVREQGLKGTYQGLTATVLKQGSNQGIRFFVMTSLRNWYRGDNPNKPMNPLITGVFGAI 229 Query: 365 AGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSAC 544 AGA S TPLDV+KTR M + A R + +++ EGL +G PR+ Sbjct: 230 AGAASVFGNTPLDVIKTR-MQGLEAHKYRNTLDCGLQILRNEGLKAFYKGTVPRLGRVCL 288 Query: 545 FAAIGYCAFE 574 AI + ++ Sbjct: 289 DVAIVFIIYD 298 Score = 45.4 bits (106), Expect = 1e-04 Identities = 27/82 (32%), Positives = 43/82 (52%), Gaps = 2/82 (2%) Frame = +2 Query: 335 PGESVLCGALAGAISAGLTTPLDVVKTRLM--TRVGAQGSRTVVGTMQEVIAEEGLMGLS 508 PG+++L G LAG I +T P + VKT+L R R + +++ + GL+GL Sbjct: 25 PGKAILAGGLAGGIEICITFPTEYVKTQLQLDERSHPPRYRGIGDCVRQTVRSHGLLGLY 84 Query: 509 RGIGPRVLHSACFAAIGYCAFE 574 RG+ + S AA+ + FE Sbjct: 85 RGLSSLLYGSIPKAAVRFGTFE 106 Score = 45.1 bits (105), Expect = 2e-04 Identities = 32/136 (23%), Positives = 61/136 (44%), Gaps = 3/136 (2%) Frame = +2 Query: 185 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGAL 364 Q +++ G GLY G ++ L ++P + + +FE+L + T G +LCG Sbjct: 73 QTVRSHGLLGLYRGLSSLLYGSIPKAAVRFGTFEFLSNHMRDAQGRLDSTRG--LLCGLG 130 Query: 365 AGAISAGLTT-PLDVVKTRLM--TRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLH 535 AG A + P++ +K + + + R ++E++ E+GL G +G+ VL Sbjct: 131 AGVPEAVVVVCPMETIKVKFIHDQTSASPKYRGFFHGVREIVREQGLKGTYQGLTATVLK 190 Query: 536 SACFAAIGYCAFETAR 583 I + + R Sbjct: 191 QGSNQGIRFFVMTSLR 206
>UCP3_PIG (O97649) Mitochondrial uncoupling protein 3 (UCP 3)| Length = 308 Score = 47.0 bits (110), Expect = 5e-05 Identities = 37/149 (24%), Positives = 67/149 (44%), Gaps = 6/149 (4%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSK-SNAPNLTPGESVLC 355 +L +++ +G Y G A L R + + ++ +K K S+ ++T +L Sbjct: 62 ILTMVRNEGPRSPYNGLVAGLQRQMSFASIRIGLYDSVKQLYTPKGSDHSSITT--RILA 119 Query: 356 GALAGAISAGLTTPLDVVKTRLMTRV--GAQGSRTVVGTM---QEVIAEEGLMGLSRGIG 520 G GA++ P DVVK R + G + +R GTM + + EEG+ GL +GI Sbjct: 120 GCTTGAMAVTCAQPTDVVKVRFQASIHAGPRSNRKYSGTMDAYRTIAREEGVRGLWKGIL 179 Query: 521 PRVLHSACFAAIGYCAFETARLMILKSYL 607 P + +A ++ + +L +L Sbjct: 180 PNITRNAIVNCAEMVTYDVIKEKVLDYHL 208 Score = 39.3 bits (90), Expect = 0.010 Identities = 35/169 (20%), Positives = 70/169 (41%), Gaps = 8/169 (4%) Frame = +2 Query: 116 PKELITQRLQS----GAATGRSWQVLLQILQT----DGFFGLYAGYAATLLRNLPAGVLS 271 P +++ R Q+ G + R + + +T +G GL+ G + RN Sbjct: 133 PTDVVKVRFQASIHAGPRSNRKYSGTMDAYRTIAREEGVRGLWKGILPNITRNAIVNCAE 192 Query: 272 YSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSR 451 +++ +K L + P V AG + + +P+DVVKTR M Q + Sbjct: 193 MVTYDVIKEKVLDYHLLTDNLPCHFVSAFG-AGFCATVVASPVDVVKTRYMNSPPGQ-YQ 250 Query: 452 TVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMILK 598 + M +++ +EG +G P L + + + ++E + ++K Sbjct: 251 NPLDCMLKMVTQEGPTAFYKGFTPSFLRLGSWNVVMFVSYEQLKRALMK 299
>M2OM_HUMAN (Q02978) Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP)| (Solute carrier family 25 member 11) Length = 313 Score = 46.6 bits (109), Expect = 6e-05 Identities = 47/176 (26%), Positives = 72/176 (40%), Gaps = 14/176 (7%) Frame = +2 Query: 116 PKELITQRLQ---SGAATGR---SWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYS 277 P +L+ R+Q GA T S+ L IL+ +G G+Y G +A LLR Sbjct: 40 PLDLVKNRMQLSGEGAKTREYKTSFHALTSILKAEGLRGIYTGLSAGLLRQATYTTTRLG 99 Query: 278 SFEYLKAFALSKSNAPNLTPG--ESVLCGALAGAISAGLTTPLDVVKTRLMTRVG----- 436 + L P PG + G AGA A + TP +V R MT G Sbjct: 100 IYTVLFERLTGADGTP---PGFLLKAVIGMTAGATGAFVGTPAEVALIR-MTADGRLPAD 155 Query: 437 -AQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMILKS 601 +G + V + + EEG++ L RG P + + A ++ ++ +L S Sbjct: 156 QRRGYKNVFNALIRITREEGVLTLWRGCIPTMARAVVVNAAQLASYSQSKQFLLDS 211 Score = 39.3 bits (90), Expect = 0.010 Identities = 30/125 (24%), Positives = 53/125 (42%), Gaps = 7/125 (5%) Frame = +2 Query: 170 WQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESV 349 + L++I + +G L+ G T+ R + +S+ K F L +++ Sbjct: 164 FNALIRITREEGVLTLWRGCIPTMARAVVVNAAQLASYSQSKQFLLDSGYF-----SDNI 218 Query: 350 LCGALAGAISAGLTT----PLDVVKTRLMTRVGAQGS---RTVVGTMQEVIAEEGLMGLS 508 LC A IS +TT P+D+ KTR+ G + + + +V+ EG L Sbjct: 219 LCHFCASMISGLVTTAASMPVDIAKTRIQNMRMIDGKPEYKNGLDVLFKVVRYEGFFSLW 278 Query: 509 RGIGP 523 +G P Sbjct: 279 KGFTP 283 Score = 32.0 bits (71), Expect = 1.6 Identities = 20/71 (28%), Positives = 35/71 (49%), Gaps = 5/71 (7%) Frame = +2 Query: 350 LCGALAGAISAGLTTPLDVVKTRLMTRVGAQGS-----RTVVGTMQEVIAEEGLMGLSRG 514 L G LAG + PLD+VK R+ ++ +G+ +T + ++ EGL G+ G Sbjct: 25 LFGGLAGMGATVFVQPLDLVKNRM--QLSGEGAKTREYKTSFHALTSILKAEGLRGIYTG 82 Query: 515 IGPRVLHSACF 547 + +L A + Sbjct: 83 LSAGLLRQATY 93
>UCP3_HUMAN (P55916) Mitochondrial uncoupling protein 3 (UCP 3)| Length = 312 Score = 46.6 bits (109), Expect = 6e-05 Identities = 36/149 (24%), Positives = 65/149 (43%), Gaps = 6/149 (4%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 358 +L +++T+G Y G A L R + + ++ +K K A N + +L G Sbjct: 65 ILTMVRTEGPCSPYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKG-ADNSSLTTRILAG 123 Query: 359 ALAGAISAGLTTPLDVVKTRLMTRV---GAQGSRTVVGTM---QEVIAEEGLMGLSRGIG 520 GA++ P DVVK R + ++ R GTM + + EEG+ GL +G Sbjct: 124 CTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTL 183 Query: 521 PRVLHSACFAAIGYCAFETARLMILKSYL 607 P ++ +A ++ + +L +L Sbjct: 184 PNIMRNAIVNCAEVVTYDILKEKLLDYHL 212 Score = 39.3 bits (90), Expect = 0.010 Identities = 32/137 (23%), Positives = 59/137 (43%) Frame = +2 Query: 188 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 367 I + +G GL+ G ++RN +++ LK L + P V A Sbjct: 169 IAREEGVRGLWKGTLPNIMRNAIVNCAEVVTYDILKEKLLDYHLLTDNFPCHFVSAFG-A 227 Query: 368 GAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACF 547 G + + +P+DVVKTR M Q + + M +++A+EG +G P L + Sbjct: 228 GFCATVVASPVDVVKTRYMNSPPGQ-YFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSW 286 Query: 548 AAIGYCAFETARLMILK 598 + + +E + ++K Sbjct: 287 NVVMFVTYEQLKRALMK 303
>ODC_PONPY (Q5RFB7) Mitochondrial 2-oxodicarboxylate carrier (Solute carrier| family 25 member 21) Length = 299 Score = 46.6 bits (109), Expect = 6e-05 Identities = 46/176 (26%), Positives = 77/176 (43%), Gaps = 15/176 (8%) Frame = +2 Query: 110 MVPKELITQR--LQSGAATGRSWQVLLQ----ILQTDGFFGLYAGYAATLLRNLPAGVLS 271 M P +++ R +Q A S++ L+ I QT+ FG Y G +L P + Sbjct: 31 MHPLDVVKTRFQIQRCATDPNSYKSLVDSFRMIFQTERLFGFYKGILPPILAETPKRAVK 90 Query: 272 YSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSR 451 + +FE K S +P LT + G +G A + P +VVK VG Q +R Sbjct: 91 FFTFEQYKKLLGYVSLSPALT---FTIAGLGSGLTEAIVVNPFEVVK------VGLQANR 141 Query: 452 -------TVVGTMQEVIAEE--GLMGLSRGIGPRVLHSACFAAIGYCAFETARLMI 592 + VG +++I +E GL GL++G+ + F + + + + MI Sbjct: 142 NTFAKQPSTVGYARQIIKKEGWGLQGLNKGLTATLGRHGVFNMVYFGFYYNVKNMI 197 Score = 46.2 bits (108), Expect = 8e-05 Identities = 40/137 (29%), Positives = 63/137 (45%), Gaps = 7/137 (5%) Frame = +2 Query: 185 QILQTDGFF--GLYAGYAATLLRNLPAGVLS--YSSFEYLKAFALSKSNAPNLTPGESVL 352 QI++ +G+ GL G ATL R+ GV + Y F Y + + P L Sbjct: 156 QIIKKEGWGLQGLNKGLTATLGRH---GVFNMVYFGFYYNVKNMIPVNKDPTLEFLRKFG 212 Query: 353 CGALAGAISAGLTTPLDVVKTRLMTRVGAQGS---RTVVGTMQEVIAEEGLMGLSRGIGP 523 G L+G I++ + P DV K+R+ G RT TM V EEG++ L +G+ P Sbjct: 213 IGLLSGTIASVINIPFDVAKSRIQGPQPVPGEIKYRTCFKTMATVYQEEGILALYKGLLP 272 Query: 524 RVLHSACFAAIGYCAFE 574 +++ A+ +E Sbjct: 273 KIMRLGPGGAVMLLVYE 289 Score = 38.1 bits (87), Expect = 0.022 Identities = 23/85 (27%), Positives = 40/85 (47%), Gaps = 3/85 (3%) Frame = +2 Query: 347 VLCGALAGAISAGLTTPLDVVKTRLMTR---VGAQGSRTVVGTMQEVIAEEGLMGLSRGI 517 ++ G AG + L PLDVVKTR + +++V + + + E L G +GI Sbjct: 17 IVAGGSAGLVEICLMHPLDVVKTRFQIQRCATDPNSYKSLVDSFRMIFQTERLFGFYKGI 76 Query: 518 GPRVLHSACFAAIGYCAFETARLMI 592 P +L A+ + FE + ++ Sbjct: 77 LPPILAETPKRAVKFFTFEQYKKLL 101
>TXTP_RAT (P32089) Tricarboxylate transport protein, mitochondrial precursor| (Citrate transport protein) (CTP) (Tricarboxylate carrier protein) (Solute carrier family 25 member 1) Length = 311 Score = 46.6 bits (109), Expect = 6e-05 Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 2/97 (2%) Frame = +2 Query: 290 LKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLM--TRVGAQGSRTVVG 463 L A A A PG+++L G LAG I +T P + VKT+L R R + Sbjct: 10 LTAAAPGSGKAKLTHPGKAILAGGLAGGIEICITFPTEYVKTQLQLDERANPPRYRGIGD 69 Query: 464 TMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFE 574 +++ + G++GL RG+ + S AA+ + FE Sbjct: 70 CVRQTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGMFE 106 Score = 45.1 bits (105), Expect = 2e-04 Identities = 34/130 (26%), Positives = 59/130 (45%) Frame = +2 Query: 185 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGAL 364 +I++ G G Y G AT+L+ + + L+ + + + P + + GA+ Sbjct: 170 EIVREQGLKGTYQGLTATVLKQGSNQAIRFFVMTSLRNWYQGDNPNKPMNPLITGVFGAV 229 Query: 365 AGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSAC 544 AGA S TPLDV+KTR M + A R + +++ EG +G PR+ Sbjct: 230 AGAASVFGNTPLDVIKTR-MQGLEAHKYRNTLDCGVQILKNEGPKAFYKGTVPRLGRVCL 288 Query: 545 FAAIGYCAFE 574 AI + ++ Sbjct: 289 DVAIVFVIYD 298 Score = 45.1 bits (105), Expect = 2e-04 Identities = 33/136 (24%), Positives = 60/136 (44%), Gaps = 3/136 (2%) Frame = +2 Query: 185 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGAL 364 Q +++ G GLY G ++ L ++P + + FE+L + L +LCG Sbjct: 73 QTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGMFEFLSNH--MRDAQGRLDSRRGLLCGLG 130 Query: 365 AGAISAGLTT-PLDVVKTRLMTRVGAQGS--RTVVGTMQEVIAEEGLMGLSRGIGPRVLH 535 AG A + P++ VK + + + R ++E++ E+GL G +G+ VL Sbjct: 131 AGVAEAVVVVCPMETVKVKFIHDQTSSNPKYRGFFHGVREIVREQGLKGTYQGLTATVLK 190 Query: 536 SACFAAIGYCAFETAR 583 AI + + R Sbjct: 191 QGSNQAIRFFVMTSLR 206
>ODC_RAT (Q99JD3) Mitochondrial 2-oxodicarboxylate carrier (Solute carrier| family 25 member 21) Length = 298 Score = 46.6 bits (109), Expect = 6e-05 Identities = 35/115 (30%), Positives = 54/115 (46%), Gaps = 5/115 (4%) Frame = +2 Query: 203 GFFGLYAGYAATLLRNLPAGV--LSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAI 376 GF GL G+ ATL R+ G+ ++Y F Y + S P L G ++G + Sbjct: 163 GFQGLNKGFTATLGRH---GIFNMTYFGFYYNVKDNIPSSKDPTLEFLRKFGIGFVSGTV 219 Query: 377 SAGLTTPLDVVKTRLMTRVGAQGS---RTVVGTMQEVIAEEGLMGLSRGIGPRVL 532 + P DV K+R+ G R TM+ V EEG++ L +G+ P+V+ Sbjct: 220 GSVFNIPFDVAKSRIQGPQPVPGEIKYRGCFKTMETVYREEGILALYKGLLPKVM 274 Score = 45.4 bits (106), Expect = 1e-04 Identities = 38/127 (29%), Positives = 59/127 (46%), Gaps = 3/127 (2%) Frame = +2 Query: 143 QSGAATGRSWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNA 322 QS + S+QV I +T+G FG Y G +L P + +S+FE K F S + Sbjct: 50 QSYKSLRDSFQV---IFRTEGLFGFYKGIIPPILAETPKRAVKFSTFELYKKFLGYMSLS 106 Query: 323 PNLTPGESVLCGALAGAISAGLTTPLDVVKTRL-MTRVGAQGSRTVVGTMQEVIAEE--G 493 P LT + G +G A + P +VVK L + R + +++I +E G Sbjct: 107 PGLT---FPIAGLGSGLTEAVVVNPFEVVKVGLQVNRNMFTEQPSTFAYARQIIKKEGWG 163 Query: 494 LMGLSRG 514 GL++G Sbjct: 164 FQGLNKG 170 Score = 42.4 bits (98), Expect = 0.001 Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 3/79 (3%) Frame = +2 Query: 347 VLCGALAGAISAGLTTPLDVVKTRLMTR---VGAQGSRTVVGTMQEVIAEEGLMGLSRGI 517 V G AG + L PLDVVKTR + Q +++ + Q + EGL G +GI Sbjct: 16 VAAGGCAGLVEICLMHPLDVVKTRFQVQRSVTDPQSYKSLRDSFQVIFRTEGLFGFYKGI 75 Query: 518 GPRVLHSACFAAIGYCAFE 574 P +L A+ + FE Sbjct: 76 IPPILAETPKRAVKFSTFE 94
>RIM2_YEAST (P38127) Mitochondrial carrier protein RIM2| Length = 377 Score = 46.2 bits (108), Expect = 8e-05 Identities = 33/137 (24%), Positives = 63/137 (45%), Gaps = 4/137 (2%) Frame = +2 Query: 140 LQSGAATGRSWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSN 319 +Q+G + ++ + + +GF L+ G L+ +PA +++ ++ K N Sbjct: 110 IQAGTHFKETLGIIGNVYKQEGFRSLFKGLGPNLVGVIPARSINFFTYGTTKDMYAKAFN 169 Query: 320 APNLTPGESVLCGALAGAISAGLTTPLDVVKTRL-MTRVGAQGSRTVVGT---MQEVIAE 487 TP ++ A AG +A T P+ ++KTR+ + + G R + ++ VI Sbjct: 170 NGQETPMIHLMAAATAGWATATATNPIWLIKTRVQLDKAGKTSVRQYKNSWDCLKSVIRN 229 Query: 488 EGLMGLSRGIGPRVLHS 538 EG GL +G+ L S Sbjct: 230 EGFTGLYKGLSASYLGS 246 Score = 38.5 bits (88), Expect = 0.017 Identities = 28/123 (22%), Positives = 51/123 (41%), Gaps = 27/123 (21%) Frame = +2 Query: 317 NAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVG-----------AQGS----- 448 N P + P + G + G A +T P D+VKTRL + + ++GS Sbjct: 46 NHPTVKPWVHFVAGGIGGMAGAVVTCPFDLVKTRLQSDIFLKAYKSQAVNISKGSTRPKS 105 Query: 449 -----------RTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMIL 595 + +G + V +EG L +G+GP ++ +I + + T + M Sbjct: 106 INYVIQAGTHFKETLGIIGNVYKQEGFRSLFKGLGPNLVGVIPARSINFFTYGTTKDMYA 165 Query: 596 KSY 604 K++ Sbjct: 166 KAF 168 Score = 30.4 bits (67), Expect = 4.7 Identities = 18/63 (28%), Positives = 35/63 (55%), Gaps = 6/63 (9%) Frame = +2 Query: 116 PKELITQRL-QSGAATG-RSWQVLLQ----ILQTDGFFGLYAGYAATLLRNLPAGVLSYS 277 P E++ RL Q+ G R + L+Q I++ +G F +Y+G L+R +P ++ + Sbjct: 308 PHEVVRTRLRQTPKENGKRKYTGLVQSFKVIIKEEGLFSMYSGLTPHLMRTVPNSIIMFG 367 Query: 278 SFE 286 ++E Sbjct: 368 TWE 370
>MFTC_HUMAN (Q9H2D1) Mitochondrial folate transporter/carrier (Solute carrier| family 25 member 32) Length = 315 Score = 46.2 bits (108), Expect = 8e-05 Identities = 39/142 (27%), Positives = 67/142 (47%), Gaps = 6/142 (4%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 358 L I + DG GLY G + + L + + +K++ ++ A L E ++ Sbjct: 69 LTTIWKLDGLRGLYQGVTPNIWGAGLSWGLYFFFYNAIKSYK-TEGRAERLEATEYLVSA 127 Query: 359 ALAGAISAGLTTPLDVVKTRLMTRVGA------QGSRTVVGTMQEVIAEEGLMGLSRGIG 520 A AGA++ +T PL V KTRLM + A + + + T+ ++ EG+ GL +G Sbjct: 128 AEAGAMTLCITNPLWVTKTRLMLQYDAVVNSPHRQYKGMFDTLVKIYKYEGVRGLYKGFV 187 Query: 521 PRVLHSACFAAIGYCAFETARL 586 P L A+ + A+E +L Sbjct: 188 PG-LFGTSHGALQFMAYELLKL 208 Score = 40.4 bits (93), Expect = 0.005 Identities = 33/145 (22%), Positives = 62/145 (42%), Gaps = 3/145 (2%) Frame = +2 Query: 170 WQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFA---LSKSNAPNLTPG 340 + L++I + +G GLY G+ L G L + ++E LK +++ L+ Sbjct: 167 FDTLVKIYKYEGVRGLYKGFVPGLF-GTSHGALQFMAYELLKLKYNQHINRLPEAQLSTV 225 Query: 341 ESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIG 520 E + AL+ + T P VV+ RL + V+ + + +EG+ G +GI Sbjct: 226 EYISVAALSKIFAVAATYPYQVVRARLQDQHMFYSG--VIDVITKTWRKEGVGGFYKGIA 283 Query: 521 PRVLHSACFAAIGYCAFETARLMIL 595 P ++ I + +E +L Sbjct: 284 PNLIRVTPACCITFVVYENVSHFLL 308
>MFTC_MACFA (Q95J75) Mitochondrial folate transporter/carrier (Solute carrier| family 25 member 32) Length = 315 Score = 45.8 bits (107), Expect = 1e-04 Identities = 39/142 (27%), Positives = 67/142 (47%), Gaps = 6/142 (4%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 358 L I + DG GLY G + + L + + +K++ ++ A L E ++ Sbjct: 69 LTTIWKLDGLRGLYQGVTPNVWGAGLSWGLYFFFYNAIKSYK-TEGRAERLEATEYLVSA 127 Query: 359 ALAGAISAGLTTPLDVVKTRLMTRVGA------QGSRTVVGTMQEVIAEEGLMGLSRGIG 520 A AGA++ +T PL V KTRLM + A + + + T+ ++ EG+ GL +G Sbjct: 128 AEAGAMTLCITNPLWVTKTRLMLQYDAVINSPHRQYKGMFDTLVKIYKYEGVRGLYKGFV 187 Query: 521 PRVLHSACFAAIGYCAFETARL 586 P L A+ + A+E +L Sbjct: 188 PG-LFGTSHGALQFMAYELLKL 208 Score = 40.8 bits (94), Expect = 0.003 Identities = 33/145 (22%), Positives = 62/145 (42%), Gaps = 3/145 (2%) Frame = +2 Query: 170 WQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFA---LSKSNAPNLTPG 340 + L++I + +G GLY G+ L G L + ++E LK +++ L+ Sbjct: 167 FDTLVKIYKYEGVRGLYKGFVPGLF-GTSHGALQFMAYELLKLKYNQHINRLPEAQLSTV 225 Query: 341 ESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIG 520 E + AL+ + T P VV+ RL + V+ + + +EG+ G +GI Sbjct: 226 EYISVAALSKIFAVAATYPYQVVRARLQDQHMFYSG--VIDVITKTWRKEGIGGFYKGIA 283 Query: 521 PRVLHSACFAAIGYCAFETARLMIL 595 P ++ I + +E +L Sbjct: 284 PNLIRVTPACCITFVVYENVSHFLL 308
>ADT_KLULA (P49382) ADP,ATP carrier protein (ADP/ATP translocase) (Adenine| nucleotide translocator) (ANT) Length = 305 Score = 45.8 bits (107), Expect = 1e-04 Identities = 33/145 (22%), Positives = 65/145 (44%), Gaps = 7/145 (4%) Frame = +2 Query: 200 DGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKA-FALSKSNAPNLTPGESVLCGALAGAI 376 +G + G A ++R P L+++ + +KA F K ++ G LAG + Sbjct: 68 EGVASFWRGNTANVIRYFPTQALNFAFKDKIKAMFGFKKEEGYAKWFAGNLASGGLAGGL 127 Query: 377 SAGLTTPLDVVKTRLMT------RVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHS 538 S LD +TRL + G + +V ++ +A +G+ GL RG P V+ Sbjct: 128 SLLFVYSLDYARTRLAADSKSAKKGGERQFNGLVDVYKKTLASDGVAGLYRGFLPSVVGI 187 Query: 539 ACFAAIGYCAFETARLMILKSYLES 613 + + + +++ + ++L LE+ Sbjct: 188 VVYRGLYFGLYDSLKPLLLTGSLEN 212 Score = 42.0 bits (97), Expect = 0.002 Identities = 36/132 (27%), Positives = 60/132 (45%), Gaps = 5/132 (3%) Frame = +2 Query: 176 VLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLC 355 V + L +DG GLY G+ +++ + L + ++ LK L+ S S L Sbjct: 163 VYKKTLASDGVAGLYRGFLPSVVGIVVYRGLYFGLYDSLKPLLLTGSLE------NSFLA 216 Query: 356 GALAG-AISAGLTT---PLDVVKTRLMTRVG-AQGSRTVVGTMQEVIAEEGLMGLSRGIG 520 L G A++ G +T PLD V+ R+M G A ++++A EG+ L +G G Sbjct: 217 SFLLGWAVTTGASTASYPLDTVRRRMMMTSGQAVKYDGAFDAFRKIVAAEGIKSLFKGCG 276 Query: 521 PRVLHSACFAAI 556 +L A + Sbjct: 277 ANILRGVAGAGV 288
>UCP1_MESAU (P04575) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 306 Score = 45.4 bits (106), Expect = 1e-04 Identities = 42/170 (24%), Positives = 74/170 (43%), Gaps = 8/170 (4%) Frame = +2 Query: 116 PKELITQRLQSGAA--------TGRSWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLS 271 P E++ RLQ+ + TG ++ I T+ F L+ G LLRN+ + Sbjct: 132 PTEVVKVRLQAQSHLHGIKPRYTG-TYNAYRIIATTESFSTLWKGTTPNLLRNVIINCVE 190 Query: 272 YSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSR 451 +++ +K ++ + P +L +AG + L +P DVVKTR + + Q Sbjct: 191 LVTYDLMKGALVNNQILADDVPCH-LLSAFVAGFCTTFLASPADVVKTRFINSLPGQ-YP 248 Query: 452 TVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMILKS 601 +V ++ +EG +G P L A + I + FE + + KS Sbjct: 249 SVPSCAMTMLTKEGPTAFFKGFVPSFLRLASWNVIMFVCFEQLKKELSKS 298 Score = 37.0 bits (84), Expect = 0.050 Identities = 28/133 (21%), Positives = 54/133 (40%), Gaps = 4/133 (3%) Frame = +2 Query: 188 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 367 + +T+G LY+G A + R + L ++ ++ + S P T G + G + Sbjct: 64 LAKTEGLPKLYSGLPAGIQRQISFASLRIGLYDTVQEYFSSGKETPP-TLGNRISAGLMT 122 Query: 368 GAISAGLTTPLDVVKTRLMTRVGAQGSR-TVVGTMQE---VIAEEGLMGLSRGIGPRVLH 535 G ++ + P +VVK RL + G + GT + E L +G P +L Sbjct: 123 GGVAVFIGQPTEVVKVRLQAQSHLHGIKPRYTGTYNAYRIIATTESFSTLWKGTTPNLLR 182 Query: 536 SACFAAIGYCAFE 574 + + ++ Sbjct: 183 NVIINCVELVTYD 195 Score = 35.0 bits (79), Expect = 0.19 Identities = 24/89 (26%), Positives = 40/89 (44%), Gaps = 5/89 (5%) Frame = +2 Query: 332 TPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRT-----VVGTMQEVIAEEGL 496 T G + +A ++ +T PLD K RL + Q S T V+GT+ + EGL Sbjct: 11 TMGVKIFSAGVAACLADIITFPLDTAKVRLQIQGEGQISSTIRYKGVLGTITTLAKTEGL 70 Query: 497 MGLSRGIGPRVLHSACFAAIGYCAFETAR 583 L G+ + FA++ ++T + Sbjct: 71 PKLYSGLPAGIQRQISFASLRIGLYDTVQ 99
>ADT2_YEAST (P18239) ADP,ATP carrier protein 2 (ADP/ATP translocase 2) (Adenine| nucleotide translocator 2) (ANT 2) Length = 318 Score = 45.4 bits (106), Expect = 1e-04 Identities = 32/144 (22%), Positives = 64/144 (44%), Gaps = 7/144 (4%) Frame = +2 Query: 200 DGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKA-FALSKSNAPNLTPGESVLCGALAGAI 376 +G + G A ++R P L+++ + +KA F K ++ G AGA+ Sbjct: 81 EGVISFWRGNTANVIRYFPTQALNFAFKDKIKAMFGFKKEEGYAKWFAGNLASGGAAGAL 140 Query: 377 SAGLTTPLDVVKTRLMT------RVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHS 538 S LD +TRL + GA+ ++ ++ + +G+ GL RG P V+ Sbjct: 141 SLLFVYSLDYARTRLAADSKSSKKGGARQFNGLIDVYKKTLKSDGVAGLYRGFLPSVVGI 200 Query: 539 ACFAAIGYCAFETARLMILKSYLE 610 + + + +++ + ++L LE Sbjct: 201 VVYRGLYFGMYDSLKPLLLTGSLE 224 Score = 41.6 bits (96), Expect = 0.002 Identities = 33/131 (25%), Positives = 60/131 (45%), Gaps = 4/131 (3%) Frame = +2 Query: 176 VLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLC 355 V + L++DG GLY G+ +++ + L + ++ LK L+ S G + Sbjct: 176 VYKKTLKSDGVAGLYRGFLPSVVGIVVYRGLYFGMYDSLKPLLLTGS-----LEGSFLAS 230 Query: 356 GALAGAISAGLTT---PLDVVKTRLMTRVG-AQGSRTVVGTMQEVIAEEGLMGLSRGIGP 523 L ++ G +T PLD V+ R+M G A +++++A EG+ L +G G Sbjct: 231 FLLGWVVTTGASTCSYPLDTVRRRMMMTSGQAVKYDGAFDCLRKIVAAEGVGSLFKGCGA 290 Query: 524 RVLHSACFAAI 556 +L A + Sbjct: 291 NILRGVAGAGV 301
>UCP1_DICGR (Q8K404) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 307 Score = 45.1 bits (105), Expect = 2e-04 Identities = 41/170 (24%), Positives = 74/170 (43%), Gaps = 8/170 (4%) Frame = +2 Query: 116 PKELITQRLQSGAA--------TGRSWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLS 271 P E++ RLQ+ + TG ++ I T+ F L+ G L+RN+ Sbjct: 133 PTEVVKVRLQAQSHLHGIKPRYTG-TYNAYRIIATTESFSTLWKGTTPNLMRNVIINRTE 191 Query: 272 YSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSR 451 +++ +K ++ + P +L +AG + L +P DVVKTR + + Q Sbjct: 192 LVTYDLMKGALVNNQILADDVPCH-LLSALVAGFCTTFLASPADVVKTRFINSLPGQ-YP 249 Query: 452 TVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMILKS 601 +V ++ +EG +G P L A + I + FE + ++KS Sbjct: 250 SVPSCAMTMLTKEGPTAFFKGFVPSFLRLASWNVIMFVCFEQLKKELMKS 299 Score = 36.2 bits (82), Expect = 0.085 Identities = 27/121 (22%), Positives = 52/121 (42%), Gaps = 4/121 (3%) Frame = +2 Query: 188 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 367 + +T+G+ LY+G A + R + L ++ ++ + S P T G + G + Sbjct: 65 LAKTEGWPKLYSGLPAGIQRQISFASLRIGLYDTVQEYFSSGKETPP-TLGNRISAGLMT 123 Query: 368 GAISAGLTTPLDVVKTRLMTRVGAQGSR-TVVGTMQE---VIAEEGLMGLSRGIGPRVLH 535 G ++ + P +VVK RL + G + GT + E L +G P ++ Sbjct: 124 GGVAVFIGQPTEVVKVRLQAQSHLHGIKPRYTGTYNAYRIIATTESFSTLWKGTTPNLMR 183 Query: 536 S 538 + Sbjct: 184 N 184
>ADT_SCHPO (Q09188) ADP,ATP carrier protein (ADP/ATP translocase) (Adenine| nucleotide translocator) (ANT) Length = 322 Score = 45.1 bits (105), Expect = 2e-04 Identities = 35/146 (23%), Positives = 63/146 (43%), Gaps = 9/146 (6%) Frame = +2 Query: 200 DGFFGLYAGYAATLLRNLPAGVLSYS---SFEYLKAFALSKSNAPNLTPGESVLCGALAG 370 +G L+ G A +LR P L+++ F+ + + + G ++ G AG Sbjct: 85 EGVISLWRGNTANVLRYFPTQALNFAFKDKFKKMFGYKKERDGYAKWFAG-NLASGGAAG 143 Query: 371 AISAGLTTPLDVVKTRLMT------RVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVL 532 A S LD +TRL + G + +V ++ +GL GL RG GP V+ Sbjct: 144 AASLLFVYSLDYARTRLANDAKSAKKGGERQFNGLVDVYRKTYRSDGLRGLYRGFGPSVV 203 Query: 533 HSACFAAIGYCAFETARLMILKSYLE 610 + + + ++T + ++L LE Sbjct: 204 GIVVYRGLYFGMYDTLKPVVLVGPLE 229 Score = 35.0 bits (79), Expect = 0.19 Identities = 29/122 (23%), Positives = 52/122 (42%), Gaps = 1/122 (0%) Frame = +2 Query: 194 QTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAGA 373 ++DG GLY G+ +++ + L + ++ LK L N S L G Sbjct: 187 RSDGLRGLYRGFGPSVVGIVVYRGLYFGMYDTLKPVVLVGPLEGNFL--ASFLLGWAVTT 244 Query: 374 ISAGLTTPLDVVKTRLMTRVG-AQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFA 550 S + PLD ++ R+M G A + ++++A+EG +G G +L A Sbjct: 245 GSGVASYPLDTIRRRMMMTSGEAVKYSSSFECGRQILAKEGARSFFKGAGANILRGVAGA 304 Query: 551 AI 556 + Sbjct: 305 GV 306
>YMC2_YEAST (P38087) Carrier protein YMC2, mitochondrial precursor| Length = 329 Score = 44.7 bits (104), Expect = 2e-04 Identities = 36/158 (22%), Positives = 65/158 (41%), Gaps = 17/158 (10%) Frame = +2 Query: 116 PKELITQRLQSGAATGRSWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLK 295 P + RLQ+ + +VL +++ +G F Y G LL + + E +K Sbjct: 54 PFDTTKVRLQTATTRTTTLEVLRNLVKNEGVFAFYKGALTPLLGVGICVSVQFGVNEAMK 113 Query: 296 AF-----------------ALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLM 424 F LS+SN L + +CG G +++ L +P++ ++ RL Sbjct: 114 RFFQNYNASKNPNMSSQDVDLSRSN--TLPLSQYYVCGLTGGVVNSFLASPIEQIRIRLQ 171 Query: 425 TRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHS 538 T+ G R G + + GL RG+ P ++ + Sbjct: 172 TQTSNGGDREFKGPWDCIKKLKAQGGLMRGLFPTMIRA 209 Score = 33.9 bits (76), Expect = 0.42 Identities = 40/162 (24%), Positives = 67/162 (41%), Gaps = 9/162 (5%) Frame = +2 Query: 116 PKELITQRLQSGAATGRS------WQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYS 277 P E I RLQ+ + G W + + L+ G GL G T++R + Sbjct: 162 PIEQIRIRLQTQTSNGGDREFKGPWDCIKK-LKAQG--GLMRGLFPTMIRAGHGLGTYFL 218 Query: 278 SFEYLKAFALSKSNAPN-LTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRV--GAQGS 448 +E L A + N + P + L GA +G + PLDVVK+ + + Sbjct: 219 VYEALVAREIGTGLTRNEIPPWKLCLFGAFSGTMLWLTVYPLDVVKSIIQNDDLRKPKYK 278 Query: 449 RTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFE 574 ++ + + A+EG+ +G GP ++ SA + FE Sbjct: 279 NSISYVAKTIYAKEGIRAFFKGFGPTMVRSAPVNGATFLTFE 320
>YE08_SCHPO (O13805) Putative mitochondrial carrier C17H9.08| Length = 326 Score = 44.7 bits (104), Expect = 2e-04 Identities = 30/120 (25%), Positives = 54/120 (45%), Gaps = 6/120 (5%) Frame = +2 Query: 170 WQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESV 349 ++ + I G GLY G+ ATL R P + + ++E ++ + + + T Sbjct: 63 YKAIKHIYHVYGLHGLYQGHTATLYRVFPYAGIKFVAYEQVRRVLI--RDPEHETHARRF 120 Query: 350 LCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLM------GLSR 511 L G+LAG S T PL++++ RL + T+ +++ E + GLSR Sbjct: 121 LSGSLAGTCSVFFTYPLELIRVRLAYITNTGKNPTLTQVTKDIFHERDFLCNKKYPGLSR 180
>ADT1_WHEAT (Q41629) ADP,ATP carrier protein 1, mitochondrial precursor| (ADP/ATP translocase 1) (Adenine nucleotide translocator 1) (ANT 1) Length = 331 Score = 44.3 bits (103), Expect = 3e-04 Identities = 34/150 (22%), Positives = 65/150 (43%), Gaps = 8/150 (5%) Frame = +2 Query: 191 LQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTP--GESVLCGAL 364 ++ +GF L+ G A ++R P L+++ +Y K K + G ++ G Sbjct: 86 IKDEGFGSLWRGNTANVIRYFPTQALNFAFKDYFKRMFNFKKDKDGYWKWFGGNLASGGA 145 Query: 365 AGAISAGLTTPLDVVKTRLMTRVGAQ---GSRT---VVGTMQEVIAEEGLMGLSRGIGPR 526 AGA S LD +TRL A G R +V ++ + +G+ GL RG Sbjct: 146 AGASSLFFVYSLDYARTRLANDAKASKGGGERQFNGLVDVYRKTLKSDGIAGLYRGFNIS 205 Query: 527 VLHSACFAAIGYCAFETARLMILKSYLESC 616 + + + + +++ + ++L L+ C Sbjct: 206 CVGIIVYRGLYFGLYDSLKPVLLTGTLQVC 235 Score = 42.0 bits (97), Expect = 0.002 Identities = 36/135 (26%), Positives = 62/135 (45%), Gaps = 8/135 (5%) Frame = +2 Query: 176 VLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLC 355 V + L++DG GLY G+ + + G++ Y F L S P L G +C Sbjct: 185 VYRKTLKSDGIAGLYRGFNISCV-----GIIVYRGLY----FGLYDSLKPVLLTGTLQVC 235 Query: 356 GALAGAIS------AGLTT-PLDVVKTRLMTRVG-AQGSRTVVGTMQEVIAEEGLMGLSR 511 + A+ AGL + P+D V+ R+M G A ++ + Q+++ +EG L + Sbjct: 236 FFASFALGWLITNGAGLASYPIDTVRRRMMMTSGEAVKYKSSLDAFQQILKKEGAKSLFK 295 Query: 512 GIGPRVLHSACFAAI 556 G G +L + A + Sbjct: 296 GAGANILRAIAGAGV 310
>M2OM_RAT (P97700) Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP)| (Solute carrier family 25 member 11) Length = 313 Score = 44.3 bits (103), Expect = 3e-04 Identities = 47/176 (26%), Positives = 70/176 (39%), Gaps = 14/176 (7%) Frame = +2 Query: 116 PKELITQRLQ---SGAATGR---SWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYS 277 P +L+ R+Q GA T S+ L IL+ +G G+Y G +A LLR Sbjct: 40 PLDLVXNRMQLSGEGAKTREYKTSFHALTSILKAEGLRGIYTGLSAGLLRQATYTTTRLG 99 Query: 278 SFEYLKAFALSKSNAPNLTPG--ESVLCGALAGAISAGLTTPLDVVKTRLMTRVG----- 436 + L P PG L G AGA A + P +V R MT G Sbjct: 100 IYTVLFERLTGADGTP---PGFLLKALIGMTAGATGAFVGPPAEVALIR-MTADGRLPAD 155 Query: 437 -AQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMILKS 601 +G + V + + EEG+ L RG P + + A ++ ++ +L S Sbjct: 156 QRRGYKNVFNALIRIAREEGVPTLWRGCIPTMARAVVVNAAQLASYSQSKQFLLDS 211 Score = 35.8 bits (81), Expect = 0.11 Identities = 31/125 (24%), Positives = 56/125 (44%), Gaps = 7/125 (5%) Frame = +2 Query: 170 WQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESV 349 + L++I + +G L+ G T+ R + +S+ K F L +++ Sbjct: 164 FNALIRIAREEGVPTLWRGCIPTMARAVVVNAAQLASYSQSKQFLLDSGYF-----SDNI 218 Query: 350 LCGALAGAISAGLTT----PLDVVKTRL--MTRVGAQGS-RTVVGTMQEVIAEEGLMGLS 508 LC A IS +TT P+D+VKTR+ M + + + + + +V+ EG L Sbjct: 219 LCHFCAIMISGLVTTAASMPVDIVKTRIQNMRMIDEKPEYKNGLDVLLKVVRYEGFFSLW 278 Query: 509 RGIGP 523 +G P Sbjct: 279 KGFTP 283 Score = 29.6 bits (65), Expect = 8.0 Identities = 19/71 (26%), Positives = 34/71 (47%), Gaps = 5/71 (7%) Frame = +2 Query: 350 LCGALAGAISAGLTTPLDVVKTRLMTRVGAQGS-----RTVVGTMQEVIAEEGLMGLSRG 514 L G LAG + PLD+V R+ ++ +G+ +T + ++ EGL G+ G Sbjct: 25 LFGGLAGMGATVFVQPLDLVXNRM--QLSGEGAKTREYKTSFHALTSILKAEGLRGIYTG 82 Query: 515 IGPRVLHSACF 547 + +L A + Sbjct: 83 LSAGLLRQATY 93
>PM47A_CANBO (P21245) Peroxisomal membrane protein PMP47A| Length = 423 Score = 43.9 bits (102), Expect = 4e-04 Identities = 44/159 (27%), Positives = 67/159 (42%), Gaps = 16/159 (10%) Frame = +2 Query: 170 WQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPN------- 328 +++L +IL+ G GLY G + L + Y +E L L++ + P Sbjct: 77 FEILKKILKDQGAKGLYNGLESALFGIAVTNFVYYYFYE-LTGKTLNRRSNPQTASNSKK 135 Query: 329 ------LTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVI--- 481 L+ +S+ GA+AG IS T P+ V TR+ QG + T++ +I Sbjct: 136 VALKKGLSVWQSMAAGAVAGTISRVATNPIWVANTRMTILSKNQGKLGKLNTIEAIIYIL 195 Query: 482 AEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMILK 598 EG L GI P L I Y FE + I+K Sbjct: 196 KNEGWQKLFTGIVP-ALFLVLNPIIQYTIFEQLKSFIVK 233
>YMC1_YEAST (P32331) Carrier protein YMC1, mitochondrial precursor| Length = 307 Score = 43.5 bits (101), Expect = 5e-04 Identities = 32/141 (22%), Positives = 64/141 (45%), Gaps = 2/141 (1%) Frame = +2 Query: 116 PKELITQRLQSGAATGRSWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLK 295 P + RLQ+ + + +V+ ++L +G G Y G L+ L + E +K Sbjct: 45 PFDTTKVRLQTSSTPTTAMEVVRKLLANEGPRGFYKGTLTPLIGVGACVSLQFGVNEAMK 104 Query: 296 AFALSKS--NAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTM 469 F ++ + L+ + CG G +++ L +P++ V+ RL T+ G+ + G + Sbjct: 105 RFFHHRNADMSSTLSLPQYYACGVTGGIVNSFLASPIEHVRIRLQTQTGSGTNAEFKGPL 164 Query: 470 QEVIAEEGLMGLSRGIGPRVL 532 + + L RG+ P +L Sbjct: 165 ECIKKLRHNKALLRGLTPTIL 185 Score = 31.2 bits (69), Expect = 2.7 Identities = 29/131 (22%), Positives = 55/131 (41%), Gaps = 5/131 (3%) Frame = +2 Query: 215 LYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNA---PNLTPGESVLCGALAGAISAG 385 L G T+LR + +E L A ++K ++ + + GAL+G Sbjct: 176 LLRGLTPTILREGHGCGTYFLVYEALIANQMNKRRGLERKDIPAWKLCIFGALSGTALWL 235 Query: 386 LTTPLDVVKTRLMT--RVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIG 559 + PLDV+K+ + T + ++ + + A G+ +G GP +L +A Sbjct: 236 MVYPLDVIKSVMQTDNLQKPKFGNSISSVAKTLYANGGIGAFFKGFGPTMLRAAPANGAT 295 Query: 560 YCAFETARLMI 592 + FE A ++ Sbjct: 296 FATFELAMRLL 306
>UCP1_PHOSU (Q9ER18) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 307 Score = 43.5 bits (101), Expect = 5e-04 Identities = 41/170 (24%), Positives = 72/170 (42%), Gaps = 8/170 (4%) Frame = +2 Query: 116 PKELITQRLQSGAA--------TGRSWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLS 271 P E++ RLQ+ + TG ++ I T+ L+ G LLRN+ Sbjct: 133 PTEVVKVRLQAQSHLHGIKPRYTG-TYNAYRIIATTESLSTLWKGTTPNLLRNVIINCTE 191 Query: 272 YSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSR 451 +++ +K ++ + P +L +AG + L +P DVVKTR + + Q Sbjct: 192 LVTYDLMKGALVNNQILADDVPCH-LLSALVAGFCTTFLASPADVVKTRFINSLPGQ-YP 249 Query: 452 TVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMILKS 601 +V + +EG +G P L A + I + FE + ++KS Sbjct: 250 SVPSCAMTMFTKEGPTAFFKGFVPSFLRLASWNVIMFVCFEQLKKELMKS 299 Score = 35.8 bits (81), Expect = 0.11 Identities = 24/89 (26%), Positives = 40/89 (44%), Gaps = 5/89 (5%) Frame = +2 Query: 332 TPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRT-----VVGTMQEVIAEEGL 496 T G + +A ++ +T PLD K RL + Q S T V+GT+ + EGL Sbjct: 12 TMGVKIFSAGVAACLADIITFPLDTAKVRLQIQGEGQTSSTIRYKGVLGTITTLAKTEGL 71 Query: 497 MGLSRGIGPRVLHSACFAAIGYCAFETAR 583 L G+ + FA++ ++T + Sbjct: 72 PKLYSGLPAGIQRQISFASLRIGLYDTVQ 100 Score = 35.4 bits (80), Expect = 0.15 Identities = 29/122 (23%), Positives = 52/122 (42%), Gaps = 5/122 (4%) Frame = +2 Query: 188 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKA-FALSKSNAPNLTPGESVLCGAL 364 + +T+G LY+G A + R + L ++ ++ F+ K P L + G + Sbjct: 65 LAKTEGLPKLYSGLPAGIQRQISFASLRIGLYDTVQEYFSSGKETPPTLV--NRISAGLM 122 Query: 365 AGAISAGLTTPLDVVKTRLMTRVGAQGSR-TVVGTMQE---VIAEEGLMGLSRGIGPRVL 532 G ++ + P +VVK RL + G + GT + E L L +G P +L Sbjct: 123 TGGVAVFIGQPTEVVKVRLQAQSHLHGIKPRYTGTYNAYRIIATTESLSTLWKGTTPNLL 182 Query: 533 HS 538 + Sbjct: 183 RN 184
>UCP1_BOVIN (P10861) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) (Fragment) Length = 288 Score = 43.5 bits (101), Expect = 5e-04 Identities = 32/147 (21%), Positives = 63/147 (42%), Gaps = 4/147 (2%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 358 ++ + +T+G LY+G A L R + L ++ ++ F + A + G + G Sbjct: 46 IITLAKTEGPVKLYSGLPAGLQRQISLASLRIGLYDTVQEFFTTGKEA---SLGSKISAG 102 Query: 359 ALAGAISAGLTTPLDVVKTRLMTRVGAQGSR-TVVGTMQE---VIAEEGLMGLSRGIGPR 526 + G ++ + P +VVK RL + G + GT + EGL GL +G P Sbjct: 103 LMTGGVAVFIGQPTEVVKVRLQAQSHLHGPKPRYTGTYNAYRIIATTEGLTGLWKGTSPN 162 Query: 527 VLHSACFAAIGYCAFETARLMILKSYL 607 + + ++ + ++K+ L Sbjct: 163 LTTNVIINCTELVTYDLMKEALVKNKL 189 Score = 38.5 bits (88), Expect = 0.017 Identities = 39/169 (23%), Positives = 71/169 (42%), Gaps = 8/169 (4%) Frame = +2 Query: 116 PKELITQRLQSGAA--------TGRSWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLS 271 P E++ RLQ+ + TG ++ I T+G GL+ G + L N+ Sbjct: 115 PTEVVKVRLQAQSHLHGPKPRYTG-TYNAYRIIATTEGLTGLWKGTSPNLTTNVIINCTE 173 Query: 272 YSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSR 451 +++ +K + + P V +AG + L++P+DVVKTR + Q + Sbjct: 174 LVTYDLMKEALVKNKLLADDVPCHFV-SAVVAGFCTTVLSSPVDVVKTRFVNSSPGQNT- 231 Query: 452 TVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMILK 598 +V ++ EG +G P L + + C FE + ++K Sbjct: 232 SVPNCAMMMLTREGPSAFFKGFVPSFLRLGSWNIMFVC-FERLKQELMK 279
>MPCP_YEAST (P23641) Mitochondrial phosphate carrier protein (Phosphate| transport protein) (PTP) (mPic 1) (Mitochondrial import receptor) (p32) Length = 311 Score = 43.5 bits (101), Expect = 5e-04 Identities = 28/76 (36%), Positives = 41/76 (53%), Gaps = 4/76 (5%) Frame = +2 Query: 359 ALAGAISAGLT----TPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPR 526 ALAGAI G T P+DVVKTR+ ++ +VG+ +++IA EG L G GP Sbjct: 21 ALAGAIGCGSTHSSMVPIDVVKTRIQLEPTVY-NKGMVGSFKQIIAGEGAGALLTGFGPT 79 Query: 527 VLHSACFAAIGYCAFE 574 +L + A + +E Sbjct: 80 LLGYSIQGAFKFGGYE 95 Score = 40.0 bits (92), Expect = 0.006 Identities = 38/162 (23%), Positives = 66/162 (40%), Gaps = 5/162 (3%) Frame = +2 Query: 110 MVPKELITQRLQSGAATGRSWQV--LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSF 283 MVP +++ R+Q V QI+ +G L G+ TLL G + + Sbjct: 35 MVPIDVVKTRIQLEPTVYNKGMVGSFKQIIAGEGAGALLTGFGPTLLGYSIQGAFKFGGY 94 Query: 284 EYLKAFALSKSNAPNLTPGE-SVLCG--ALAGAISAGLTTPLDVVKTRLMTRVGAQGSRT 454 E K F + + + SV G A+A ++ PL+ + RL+++ Q + Sbjct: 95 EVFKKFFIDNLGYDTASRYKNSVYMGSAAMAEFLADIALCPLEATRIRLVSQ--PQFANG 152 Query: 455 VVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETA 580 +VG ++ EEG+ G P + + + FE A Sbjct: 153 LVGGFSRILKEEGIGSFYSGFTPILFKQIPYNIAKFLVFERA 194
>MPCP_BOVIN (P12234) Phosphate carrier protein, mitochondrial precursor (PTP)| (Solute carrier family 25 member 3) Length = 362 Score = 43.5 bits (101), Expect = 5e-04 Identities = 37/159 (23%), Positives = 66/159 (41%), Gaps = 4/159 (2%) Frame = +2 Query: 110 MVPKELITQRLQSGAATGRS-WQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFE 286 +VP +L+ R+Q +S + L+ DGF GL G+A T + G+ + +E Sbjct: 83 LVPLDLVKCRMQVDPQKYKSIFNGFSVTLKEDGFRGLAKGWAPTFIGYSLQGLCKFGFYE 142 Query: 287 YLKAF---ALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTV 457 K L + NA + A A + P++ K R+ T+ G + T+ Sbjct: 143 VFKVLYSNMLGEENAYLWRTSLYLAASASAEFFADIALAPMEAAKVRIQTQPGY--ANTL 200 Query: 458 VGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFE 574 ++ EEGL +G+ P + + + + FE Sbjct: 201 RDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFE 239
>YFL5_YEAST (P43617) Putative mitochondrial carrier YFR045W| Length = 285 Score = 43.5 bits (101), Expect = 5e-04 Identities = 27/133 (20%), Positives = 57/133 (42%) Frame = +2 Query: 194 QTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAGA 373 QT G G AT+ R + + ++++ K ++++ + SV+ G Sbjct: 152 QTRGPAAFVQGTTATIFRQIANTSIQFTAYTAFKRLLQARNDKAS-----SVITGLATSF 206 Query: 374 ISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAA 553 +T P+DVVKTR+M++ + + M + +EG+ +G R + Sbjct: 207 TLVAMTQPIDVVKTRMMSQNAKTEYKNTLNCMYRIFVQEGMATFWKGSIFRFMKVGISGG 266 Query: 554 IGYCAFETARLMI 592 + + +E L++ Sbjct: 267 LTFTVYEQVSLLL 279
>ARG13_NEUCR (Q01356) Amino acid transporter arg-13| Length = 363 Score = 43.1 bits (100), Expect = 7e-04 Identities = 33/123 (26%), Positives = 55/123 (44%), Gaps = 13/123 (10%) Frame = +2 Query: 185 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVL---- 352 Q ++ DGF GLY G +A L+ L SS + + S + P +S L Sbjct: 90 QSIRADGFLGLYRGISAPLV----GAALENSSLFFFERIGRSLLYSSGFAPRDSELSLSA 145 Query: 353 ---CGALAGAISAGLTTPLDVVKTRLMT--RVGAQGSR----TVVGTMQEVIAEEGLMGL 505 G +GA ++ + TP+++VK ++ G G+R + ++E+ EGL G Sbjct: 146 LWFTGGFSGAFTSLILTPVELVKCKIQVPDEPGGAGARQRQLKPIPVIKEIFRHEGLRGF 205 Query: 506 SRG 514 G Sbjct: 206 WHG 208
>ADT1_BOVIN (P02722) ADP/ATP translocase 1 (Adenine nucleotide translocator 1)| (ANT 1) (ADP,ATP carrier protein 1) (Solute carrier family 25 member 4) (ADP,ATP carrier protein, heart isoform T1) Length = 297 Score = 43.1 bits (100), Expect = 7e-04 Identities = 40/151 (26%), Positives = 66/151 (43%), Gaps = 13/151 (8%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSN---------APNL 331 +++I + GF + G A ++R P L+++ + K L + A NL Sbjct: 57 VVRIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDRHKQFWRYFAGNL 116 Query: 332 TPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVG---AQGSRTVVGT-MQEVIAEEGLM 499 G + AGA S PLD +TRL VG AQ T +G + ++ +GL Sbjct: 117 ASGGA------AGATSLCFVYPLDFARTRLAADVGKGAAQREFTGLGNCITKIFKSDGLR 170 Query: 500 GLSRGIGPRVLHSACFAAIGYCAFETARLMI 592 GL +G V + A + ++TA+ M+ Sbjct: 171 GLYQGFNVSVQGIIIYRAAYFGVYDTAKGML 201 Score = 34.7 bits (78), Expect = 0.25 Identities = 29/125 (23%), Positives = 59/125 (47%), Gaps = 7/125 (5%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 358 + +I ++DG GLY G+ ++ G++ Y + Y + +K P+ ++ Sbjct: 160 ITKIFKSDGLRGLYQGFNVSV-----QGIIIYRA-AYFGVYDTAKGMLPDPKNVHIIVSW 213 Query: 359 ALAGAISA--GLTT-PLDVVKTRLMTRVGAQGSRTV----VGTMQEVIAEEGLMGLSRGI 517 +A ++A GL + P D V+ R+M + G +G+ + V +++ +EG +G Sbjct: 214 MIAQTVTAVAGLVSYPFDTVRRRMMMQSGRKGADIMYTGTVDCWRKIAKDEGPKAFFKGA 273 Query: 518 GPRVL 532 VL Sbjct: 274 WSNVL 278
>ADT2_WHEAT (Q41630) ADP,ATP carrier protein 2, mitochondrial precursor| (ADP/ATP translocase 2) (Adenine nucleotide translocator 2) (ANT 2) Length = 331 Score = 43.1 bits (100), Expect = 7e-04 Identities = 37/135 (27%), Positives = 62/135 (45%), Gaps = 8/135 (5%) Frame = +2 Query: 176 VLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLC 355 V + L++DG GLY G+ + + G++ Y F L S P L G +C Sbjct: 185 VYRKTLKSDGIAGLYRGFNISCV-----GIIVYRGLY----FGLYDSLKPVLLTGTLQVC 235 Query: 356 GALAGAIS------AGLTT-PLDVVKTRLMTRVG-AQGSRTVVGTMQEVIAEEGLMGLSR 511 + A+ AGL + P+D V+ R+M G A ++ + Q++ A+EG L + Sbjct: 236 SFASFALGWLITNGAGLASYPIDTVRRRMMMTSGEAVKYKSSLDAFQQIPAKEGAKSLFK 295 Query: 512 GIGPRVLHSACFAAI 556 G G +L + A + Sbjct: 296 GAGANILRAIAGAGV 310 Score = 43.1 bits (100), Expect = 7e-04 Identities = 34/150 (22%), Positives = 65/150 (43%), Gaps = 8/150 (5%) Frame = +2 Query: 191 LQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTP--GESVLCGAL 364 ++ +GF L+ G A ++R P L+++ +Y K K + G ++ G Sbjct: 86 IKDEGFGSLWRGNTANVIRYFPTQALNFAFKDYFKRMFNFKKDKDGYWKWFGGNLASGGA 145 Query: 365 AGAISAGLTTPLDVVKTRLMTRVGAQ---GSRT---VVGTMQEVIAEEGLMGLSRGIGPR 526 AGA S LD +TRL A G R +V ++ + +G+ GL RG Sbjct: 146 AGASSLFFVYSLDYGRTRLANDAKASKGGGDRQFNGLVDVYRKTLKSDGIAGLYRGFNIS 205 Query: 527 VLHSACFAAIGYCAFETARLMILKSYLESC 616 + + + + +++ + ++L L+ C Sbjct: 206 CVGIIVYRGLYFGLYDSLKPVLLTGTLQVC 235
>ORT1_YEAST (Q12375) Mitochondrial ornithine carrier protein| Length = 292 Score = 42.4 bits (98), Expect = 0.001 Identities = 40/164 (24%), Positives = 71/164 (43%), Gaps = 8/164 (4%) Frame = +2 Query: 110 MVPKELITQRLQSGAATGRSWQVL---LQILQTDGFFGLYAGYAATLLRNLPAGVLSYSS 280 +V +L LQ +A + +VL I+ G GL+ G + T +R GV +++ Sbjct: 130 LVKCKLQVANLQVASAKTKHTKVLPTIKAIITERGLAGLWQGQSGTFIRESFGGVAWFAT 189 Query: 281 FEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTT-----PLDVVKTRLMTRVGAQG 445 +E +K + + + ES + L SAGL P D VK+ + T Sbjct: 190 YEIVKKSLKDRHSLDDPKRDESKIWELLISGGSAGLAFNASIFPADTVKSVMQTE----- 244 Query: 446 SRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFET 577 ++ ++++ + GL G RG+G + + A + FET Sbjct: 245 HISLTNAVKKIFGKFGLKGFYRGLGITLFRAVPANAAVFYIFET 288
>LEU5_YEAST (P38702) Mitochondrial carrier protein LEU5| Length = 357 Score = 42.4 bits (98), Expect = 0.001 Identities = 23/74 (31%), Positives = 40/74 (54%) Frame = +2 Query: 200 DGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAIS 379 DG G + G++ATLLR P + + ++E ++ + + ++ G+LAG S Sbjct: 89 DGVRGFFQGHSATLLRIFPYAAVKFVAYEQIRNTLIPSKEFE--SHWRRLVSGSLAGLCS 146 Query: 380 AGLTTPLDVVKTRL 421 +T PLD+V+ RL Sbjct: 147 VFITYPLDLVRVRL 160
>ADT_CHLRE (P27080) ADP,ATP carrier protein (ADP/ATP translocase) (Adenine| nucleotide translocator) (ANT) Length = 308 Score = 42.4 bits (98), Expect = 0.001 Identities = 30/149 (20%), Positives = 66/149 (44%), Gaps = 8/149 (5%) Frame = +2 Query: 173 QVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYS-SFEYLKAFALSKSNAPNLTPGESV 349 + ++ ++ +GF L+ G A ++R P L+++ ++ + F +K ++ Sbjct: 57 ECFVRTVREEGFGSLWRGNTANVIRYFPTQALNFAFKDKFKRMFGFNKDKEYWKWFAGNM 116 Query: 350 LCGALAGAISAGLTTPLDVVKTRLMTRV-------GAQGSRTVVGTMQEVIAEEGLMGLS 508 G AGA+S LD +TRL G + +V ++ IA +G+ GL Sbjct: 117 ASGGAAGAVSLSFVYSLDYARTRLANDAKSAKKGGGDRQFNGLVDVYRKTIASDGIAGLY 176 Query: 509 RGIGPRVLHSACFAAIGYCAFETARLMIL 595 RG + + + + +++ + ++L Sbjct: 177 RGFNISCVGIVVYRGLYFGMYDSLKPVVL 205 Score = 41.2 bits (95), Expect = 0.003 Identities = 35/132 (26%), Positives = 58/132 (43%), Gaps = 5/132 (3%) Frame = +2 Query: 176 VLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLC 355 V + + +DG GLY G+ + + + L + ++ LK L A N L Sbjct: 162 VYRKTIASDGIAGLYRGFNISCVGIVVYRGLYFGMYDSLKPVVLVGPLANNF------LA 215 Query: 356 GALAG---AISAGLTT-PLDVVKTRLMTRVG-AQGSRTVVGTMQEVIAEEGLMGLSRGIG 520 L G I AGL + P+D ++ R+M G A + QE++ EG+ L +G G Sbjct: 216 AFLLGWGITIGAGLASYPIDTIRRRMMMTSGSAVKYNSSFHCFQEIVKNEGMKSLFKGAG 275 Query: 521 PRVLHSACFAAI 556 +L + A + Sbjct: 276 ANILRAVAGAGV 287
>YG2O_YEAST (P53257) Putative mitochondrial carrier YGR096W| Length = 314 Score = 42.4 bits (98), Expect = 0.001 Identities = 45/186 (24%), Positives = 78/186 (41%), Gaps = 10/186 (5%) Frame = +2 Query: 116 PKELITQRLQSGAATG------RSWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYS 277 P + I RLQ A G + +V +++ +G + G L + G +S Sbjct: 36 PMDTIKIRLQLTPANGLKPFGSQVMEVARSMIKNEGIRSFWKGNIPGSLLYVTYGSAQFS 95 Query: 278 SFE----YLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQG 445 S+ YL F L S++ GA AG S+ ++ P DV++TRL+ Sbjct: 96 SYSLFNRYLTPFGLEARL-------HSLVVGAFAGITSSIVSYPFDVLRTRLVAN-NQMH 147 Query: 446 SRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMILKSYLESCERK 625 S ++ ++++ EGL G +G + A+I + +ET R+ Y + E+ Sbjct: 148 SMSITREVRDIWKLEGLPGFFKGSIASMTTITLTASIMFGTYETIRI-----YCDENEKT 202 Query: 626 AADEMK 643 A K Sbjct: 203 TAAHKK 208
>ADT_ORYSA (P31691) ADP,ATP carrier protein, mitochondrial precursor (ADP/ATP| translocase) (Adenine nucleotide translocator) (ANT) Length = 382 Score = 42.0 bits (97), Expect = 0.002 Identities = 31/148 (20%), Positives = 63/148 (42%), Gaps = 8/148 (5%) Frame = +2 Query: 191 LQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTP--GESVLCGAL 364 ++ +GF L+ G A ++R P L+++ +Y K K + G ++ G Sbjct: 137 IKDEGFASLWRGNTANVIRYFPTQALNFAFKDYFKRLFNFKKDKDGYWKWFGGNLASGGA 196 Query: 365 AGAISAGLTTPLDVVKTRLMTRV------GAQGSRTVVGTMQEVIAEEGLMGLSRGIGPR 526 AGA S LD +TRL G + +V ++ + +G+ GL RG Sbjct: 197 AGASSLFFVYSLDYARTRLANDAKAAKGGGERQFNGLVDVYRKTLKSDGIAGLYRGFNIS 256 Query: 527 VLHSACFAAIGYCAFETARLMILKSYLE 610 + + + + +++ + ++L L+ Sbjct: 257 CVGIIVYRGLYFGMYDSLKPVVLTGSLQ 284 Score = 39.3 bits (90), Expect = 0.010 Identities = 34/129 (26%), Positives = 59/129 (45%), Gaps = 2/129 (1%) Frame = +2 Query: 176 VLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLC 355 V + L++DG GLY G+ + + + L + ++ LK L+ S N S Sbjct: 236 VYRKTLKSDGIAGLYRGFNISCVGIIVYRGLYFGMYDSLKPVVLTGSLQDNFF--ASFAL 293 Query: 356 GALAGAISAGLTT-PLDVVKTRLMTRVG-AQGSRTVVGTMQEVIAEEGLMGLSRGIGPRV 529 G L AGL + P+D V+ R+M G A ++ + +++ EG L +G G + Sbjct: 294 GWLI-TNGAGLASYPIDTVRRRMMMTSGEAVKYKSSMDAFSQILKNEGAKSLFKGAGANI 352 Query: 530 LHSACFAAI 556 L + A + Sbjct: 353 LRAIAGAGV 361
>YHM2_YEAST (Q04013) Mitochondrial DNA replication protein YHM2| Length = 314 Score = 42.0 bits (97), Expect = 0.002 Identities = 33/135 (24%), Positives = 57/135 (42%), Gaps = 7/135 (5%) Frame = +2 Query: 146 SGAATGRSWQVLLQILQTDGFFGLYAGYAATLLRNLPAGV----LSYSSFEYLKAFALSK 313 +G SW V I + +G G+ G A +R + LS + ++ Sbjct: 148 AGGVPQSSWSVFKNIYKKEGIRGINKGVNAVAIRQMTNWGSRFGLSRLVEDGIRKITGKT 207 Query: 314 SNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRV---GAQGSRTVVGTMQEVIA 484 + L P E + AL G +SA P++V++ + ++ + TV T + + Sbjct: 208 NKDDKLNPFEKIGASALGGGLSAW-NQPIEVIRVEMQSKKEDPNRPKNLTVGKTFKYIYQ 266 Query: 485 EEGLMGLSRGIGPRV 529 GL GL RG+ PR+ Sbjct: 267 SNGLKGLYRGVTPRI 281
>UCP1_RABIT (P14271) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 306 Score = 42.0 bits (97), Expect = 0.002 Identities = 31/121 (25%), Positives = 52/121 (42%), Gaps = 4/121 (3%) Frame = +2 Query: 188 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 367 + +T+G LY+G A L R + L ++ ++ F S P+L G + G Sbjct: 65 LAKTEGPLKLYSGLPAGLQRQISFASLRIGLYDTVQEFFTSGEETPSL--GSKISAGLTT 122 Query: 368 GAISAGLTTPLDVVKTRLMTRVGAQGSR-TVVGTMQE---VIAEEGLMGLSRGIGPRVLH 535 G ++ + P +VVK RL + G + GT + E L L +G P +L Sbjct: 123 GGVAVFIGQPTEVVKVRLQAQSHLHGLKPRYTGTYNAYRIIATTESLTSLWKGTTPNLLR 182 Query: 536 S 538 + Sbjct: 183 N 183 Score = 39.7 bits (91), Expect = 0.008 Identities = 39/170 (22%), Positives = 71/170 (41%), Gaps = 8/170 (4%) Frame = +2 Query: 116 PKELITQRLQSGAA--------TGRSWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLS 271 P E++ RLQ+ + TG ++ I T+ L+ G LLRN+ Sbjct: 132 PTEVVKVRLQAQSHLHGLKPRYTG-TYNAYRIIATTESLTSLWKGTTPNLLRNVIINCTE 190 Query: 272 YSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSR 451 +++ +K + + P V +AG + L++P+DVVKTR + Q + Sbjct: 191 LVTYDLMKGALVRNEILADDVPCHFV-SALIAGFCTTLLSSPVDVVKTRFINSPPGQYA- 248 Query: 452 TVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMILKS 601 +V + +EG +G P L + I + FE + +++S Sbjct: 249 SVPNCAMTMFTKEGPTAFFKGFVPSFLRLGSWNVIMFVCFEKLKGELMRS 298
>ADT3_BOVIN (P32007) ADP/ATP translocase 3 (Adenine nucleotide translocator 2)| (ANT 3) (ADP,ATP carrier protein 3) (Solute carrier family 25 member 6) (ADP,ATP carrier protein, isoform T2) (ANT 2) Length = 297 Score = 42.0 bits (97), Expect = 0.002 Identities = 36/147 (24%), Positives = 63/147 (42%), Gaps = 9/147 (6%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 358 +++I + G + G A ++R P L+++ + K L T G Sbjct: 57 IVRIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLG--GVDKRTQFWRYFAG 114 Query: 359 ALAGAISAGLTT-----PLDVVKTRLMTRVGAQGS----RTVVGTMQEVIAEEGLMGLSR 511 LA +AG T+ PLD +TRL VG GS R + + ++ +G+ GL + Sbjct: 115 NLASGGAAGATSLCFVYPLDFARTRLAADVGKSGSEREFRGLGDCLVKITKSDGIRGLYQ 174 Query: 512 GIGPRVLHSACFAAIGYCAFETARLMI 592 G V + A + ++TA+ M+ Sbjct: 175 GFNVSVQGIIIYRAAYFGIYDTAKGML 201 Score = 36.6 bits (83), Expect = 0.065 Identities = 29/125 (23%), Positives = 60/125 (48%), Gaps = 7/125 (5%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 358 L++I ++DG GLY G+ ++ G++ Y + Y + +K P+ V+ Sbjct: 160 LVKITKSDGIRGLYQGFNVSV-----QGIIIYRA-AYFGIYDTAKGMLPDPKNTHIVVSW 213 Query: 359 ALAGAISAG---LTTPLDVVKTRLMTRVGAQGS----RTVVGTMQEVIAEEGLMGLSRGI 517 +A ++A ++ P D V+ R+M + G +G+ + V ++++ +EG +G Sbjct: 214 MIAQTVTAVAGVVSYPFDTVRRRMMMQSGRKGADIMYKGTVDCWRKILKDEGGKAFFKGA 273 Query: 518 GPRVL 532 VL Sbjct: 274 WSNVL 278
>ADT1_RABIT (O46373) ADP/ATP translocase 1 (Adenine nucleotide translocator 1)| (ANT 1) (ADP,ATP carrier protein 1) (Solute carrier family 25 member 4) (30 kDa calsequestrin-binding protein) (CSQ-binding 30 kDa protein) Length = 297 Score = 42.0 bits (97), Expect = 0.002 Identities = 39/151 (25%), Positives = 66/151 (43%), Gaps = 13/151 (8%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSN---------APNL 331 +++I + GF + G A ++R P L+++ + K L + A NL Sbjct: 57 VVRIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDRHKQFWRYFAGNL 116 Query: 332 TPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVG---AQGSRTVVGT-MQEVIAEEGLM 499 G + AGA S PLD +TRL VG AQ + +G + ++ +GL Sbjct: 117 ASGGA------AGATSLCFVYPLDFARTRLAADVGKGAAQREFSGLGNCLTKIFKSDGLR 170 Query: 500 GLSRGIGPRVLHSACFAAIGYCAFETARLMI 592 GL +G V + A + ++TA+ M+ Sbjct: 171 GLYQGFNVSVQGIIIYRAAYFGVYDTAKGML 201 Score = 36.2 bits (82), Expect = 0.085 Identities = 30/125 (24%), Positives = 59/125 (47%), Gaps = 7/125 (5%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 358 L +I ++DG GLY G+ ++ G++ Y + Y + +K P+ ++ Sbjct: 160 LTKIFKSDGLRGLYQGFNVSV-----QGIIIYRA-AYFGVYDTAKGMLPDPKNVHIIVSW 213 Query: 359 ALAGAISA--GLTT-PLDVVKTRLMTRVGAQGSRTV----VGTMQEVIAEEGLMGLSRGI 517 +A ++A GL + P D V+ R+M + G +G+ + V +++ +EG +G Sbjct: 214 MIAQTVTAVAGLVSYPFDTVRRRMMMQSGRKGADIMYTGTVDCWKKIAKDEGAKAFFKGA 273 Query: 518 GPRVL 532 VL Sbjct: 274 WSNVL 278
>ADT_CHLKE (P31692) ADP,ATP carrier protein (ADP/ATP translocase) (Adenine| nucleotide translocator) (ANT) Length = 339 Score = 41.6 bits (96), Expect = 0.002 Identities = 35/150 (23%), Positives = 63/150 (42%), Gaps = 11/150 (7%) Frame = +2 Query: 182 LQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGE------ 343 +++ G + G A ++R P +++ + +K P +P Sbjct: 94 VRVSSEQGVASFWRGNLANVVRYFPTQAFNFAFKDTIKGLF------PKYSPKTDFWRFF 147 Query: 344 --SVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVG---TMQEVIAEEGLMGLS 508 ++ G LAGA S + PLD +TRL VG+ SR G + +V+ G M L Sbjct: 148 VVNLASGGLAGAGSLLIVYPLDFARTRLAADVGSGKSREFTGLVDCLSKVVKRGGPMALY 207 Query: 509 RGIGPRVLHSACFAAIGYCAFETARLMILK 598 +G G V + + ++TA+ ++ K Sbjct: 208 QGFGVSVQGIIVYRGAYFGLYDTAKGVLFK 237 Score = 35.4 bits (80), Expect = 0.15 Identities = 35/151 (23%), Positives = 61/151 (40%), Gaps = 9/151 (5%) Frame = +2 Query: 116 PKELITQRLQSGAATGRSWQV------LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYS 277 P + RL + +G+S + L ++++ G LY G+ ++ + + Sbjct: 167 PLDFARTRLAADVGSGKSREFTGLVDCLSKVVKRGGPMALYQGFGVSVQGIIVYRGAYFG 226 Query: 278 SFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTV 457 ++ K N +V AGA L+ P D V+ RLM + G G R Sbjct: 227 LYDTAKGVLFKDERTANFFAKWAVAQAVTAGA--GVLSYPFDTVRRRLMMQSG--GERQY 282 Query: 458 VGTM---QEVIAEEGLMGLSRGIGPRVLHSA 541 GT+ ++V +EG+ +G VL A Sbjct: 283 NGTIDCWRKVAQQEGMKAFFKGAWSNVLRGA 313
>ADT1_RAT (Q05962) ADP/ATP translocase 1 (Adenine nucleotide translocator 1)| (ANT 1) (ADP,ATP carrier protein 1) (Solute carrier family 25 member 4) Length = 297 Score = 41.6 bits (96), Expect = 0.002 Identities = 37/151 (24%), Positives = 64/151 (42%), Gaps = 13/151 (8%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSN---------APNL 331 +++I + GF + G A ++R P L+++ + K L + A NL Sbjct: 57 VVRIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDRHKQFWRYFAGNL 116 Query: 332 TPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRT----VVGTMQEVIAEEGLM 499 G + AGA S PLD +TRL VG S+ + + ++ +GL Sbjct: 117 ASGGA------AGATSLCFVYPLDFARTRLAADVGKGSSQREFNGLGDCLTKIFKSDGLK 170 Query: 500 GLSRGIGPRVLHSACFAAIGYCAFETARLMI 592 GL +G V + A + ++TA+ M+ Sbjct: 171 GLYQGFSVSVQGIIIYRAAYFGVYDTAKGML 201 Score = 37.4 bits (85), Expect = 0.038 Identities = 30/125 (24%), Positives = 61/125 (48%), Gaps = 7/125 (5%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 358 L +I ++DG GLY G++ ++ G++ Y + Y + +K P+ ++ Sbjct: 160 LTKIFKSDGLKGLYQGFSVSV-----QGIIIYRA-AYFGVYDTAKGMLPDPKNVHIIVSW 213 Query: 359 ALAGAISA--GLTT-PLDVVKTRLMTRVGAQGSRTV----VGTMQEVIAEEGLMGLSRGI 517 +A +++A GL + P D V+ R+M + G +G+ + V +++ +EG +G Sbjct: 214 MIAQSVTAVAGLVSYPFDTVRRRMMMQSGRKGADIMYTGTVDCWRKIAKDEGRKAFFKGA 273 Query: 518 GPRVL 532 VL Sbjct: 274 WSNVL 278
>ADT1_MOUSE (P48962) ADP/ATP translocase 1 (Adenine nucleotide translocator 1)| (ANT 1) (ADP,ATP carrier protein 1) (Solute carrier family 25 member 4) (ADP,ATP carrier protein, heart/skeletal muscle isoform T1) (mANC1) Length = 297 Score = 41.6 bits (96), Expect = 0.002 Identities = 37/151 (24%), Positives = 64/151 (42%), Gaps = 13/151 (8%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSN---------APNL 331 +++I + GF + G A ++R P L+++ + K L + A NL Sbjct: 57 VVRIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDRHKQFWRYFAGNL 116 Query: 332 TPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRT----VVGTMQEVIAEEGLM 499 G + AGA S PLD +TRL VG S+ + + ++ +GL Sbjct: 117 ASGGA------AGATSLCFVYPLDFARTRLAADVGKGSSQREFNGLGDCLTKIFKSDGLK 170 Query: 500 GLSRGIGPRVLHSACFAAIGYCAFETARLMI 592 GL +G V + A + ++TA+ M+ Sbjct: 171 GLYQGFSVSVQGIIIYRAAYFGVYDTAKGML 201 Score = 37.7 bits (86), Expect = 0.029 Identities = 31/125 (24%), Positives = 63/125 (50%), Gaps = 7/125 (5%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 358 L +I ++DG GLY G++ ++ G++ Y + Y + +K P+ ++ Sbjct: 160 LTKIFKSDGLKGLYQGFSVSV-----QGIIIYRA-AYFGVYDTAKGMLPDPKNVHIIVSW 213 Query: 359 ALAGAISA--GLTT-PLDVVKTRLMTRVGAQGSRTV-VGTM---QEVIAEEGLMGLSRGI 517 +A +++A GL + P D V+ R+M + G +G+ + GT+ +++ +EG +G Sbjct: 214 MIAQSVTAVAGLVSYPFDTVRRRMMMQSGRKGADIMYTGTLDCWRKIAKDEGANAFFKGA 273 Query: 518 GPRVL 532 VL Sbjct: 274 WSNVL 278
>DIC1_CANGA (Q6FTN2) Mitochondrial dicarboxylate transporter (Dicarboxylate| carrier 1) Length = 295 Score = 41.6 bits (96), Expect = 0.002 Identities = 28/88 (31%), Positives = 44/88 (50%), Gaps = 3/88 (3%) Frame = +2 Query: 116 PKELITQRLQSGAATGRSW-QVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYL 292 P +L RLQ+ + Q+L IL+ +G GLYAG +A+LLR + ++ L Sbjct: 26 PLDLTKVRLQAAPIPKPTIVQMLRSILKNEGIVGLYAGLSASLLRQCTYTTARFGMYDAL 85 Query: 293 KAFALSKSNAPNL--TPGESVLCGALAG 370 K + + N+ G S++ GAL G Sbjct: 86 KEHVIPRDKLTNMWYLLGASMVSGALGG 113 Score = 36.2 bits (82), Expect = 0.085 Identities = 30/135 (22%), Positives = 58/135 (42%), Gaps = 3/135 (2%) Frame = +2 Query: 179 LLQILQTDGFFGLY-AGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLC 355 +++I + +G L+ G+ ++R + +++ K F ++K N + Sbjct: 147 MVKIYKAEGAKSLFLTGWKPNMVRGVLMTASQVVTYDMFKNFLVTKYNMDPKKNSTHLTS 206 Query: 356 GALAGAISAGLTTPLDVVKTRLMTRVGAQGSR--TVVGTMQEVIAEEGLMGLSRGIGPRV 529 LAG ++ + +P DV+KT +M G + + E I +EG + RG P Sbjct: 207 SLLAGFVATTVCSPADVIKTIVMNAHKKPGHNHDSSFKILMEAINKEGPSFMFRGWVPSF 266 Query: 530 LHSACFAAIGYCAFE 574 A F + + A E Sbjct: 267 TRLAPFTMLIFFAME 281 Score = 34.7 bits (78), Expect = 0.25 Identities = 22/76 (28%), Positives = 35/76 (46%) Frame = +2 Query: 356 GALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLH 535 G AG + T PLD+ K RL + T+V ++ ++ EG++GL G+ +L Sbjct: 13 GGAAGIFAVMNTHPLDLTKVRL--QAAPIPKPTIVQMLRSILKNEGIVGLYAGLSASLLR 70 Query: 536 SACFAAIGYCAFETAR 583 C + TAR Sbjct: 71 Q--------CTYTTAR 78
>UCP1_RAT (P04633) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 306 Score = 41.2 bits (95), Expect = 0.003 Identities = 32/138 (23%), Positives = 59/138 (42%) Frame = +2 Query: 188 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 367 I T+ L+ G L+RN+ +++ +K ++ + P +L +A Sbjct: 163 IATTESLSTLWKGTTPNLMRNVIINCTELVTYDLMKGALVNHHILADDVPCH-LLSALVA 221 Query: 368 GAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACF 547 G + L +P+DVVKTR + + Q +V + +EG +G P L + Sbjct: 222 GFCTTLLASPVDVVKTRFINSLPGQ-YPSVPSCAMTMYTKEGPAAFFKGFAPSFLRLGSW 280 Query: 548 AAIGYCAFETARLMILKS 601 I + FE + ++KS Sbjct: 281 NVIMFVCFEQLKKELMKS 298 Score = 35.4 bits (80), Expect = 0.15 Identities = 23/89 (25%), Positives = 40/89 (44%), Gaps = 5/89 (5%) Frame = +2 Query: 332 TPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRT-----VVGTMQEVIAEEGL 496 T G + ++ ++ +T PLD K RL + Q S T V+GT+ + EGL Sbjct: 11 TMGVKIFSAGVSACLADIITFPLDTAKVRLQIQGEGQASSTIRYKGVLGTITTLAKTEGL 70 Query: 497 MGLSRGIGPRVLHSACFAAIGYCAFETAR 583 L G+ + FA++ ++T + Sbjct: 71 PKLYSGLPAGIQRQISFASLRIGLYDTVQ 99
>ADT1_YEAST (P04710) ADP,ATP carrier protein 1 (ADP/ATP translocase 1) (Adenine| nucleotide translocator 1) (ANT 1) Length = 309 Score = 41.2 bits (95), Expect = 0.003 Identities = 32/131 (24%), Positives = 56/131 (42%), Gaps = 4/131 (3%) Frame = +2 Query: 176 VLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLC 355 V + L+TDG GLY G+ ++L + L + ++ K L+ G V Sbjct: 167 VYKKTLKTDGLLGLYRGFVPSVLGIIVYRGLYFGLYDSFKPVLLT-----GALEGSFVAS 221 Query: 356 GALAGAISAGLTT---PLDVVKTRLMTRVGAQGSRT-VVGTMQEVIAEEGLMGLSRGIGP 523 L I+ G +T PLD V+ R+M G + +++++ +EG L +G G Sbjct: 222 FLLGWVITMGASTASYPLDTVRRRMMMTSGQTIKYDGALDCLRKIVQKEGAYSLFKGCGA 281 Query: 524 RVLHSACFAAI 556 + A + Sbjct: 282 NIFRGVAAAGV 292 Score = 40.8 bits (94), Expect = 0.003 Identities = 32/147 (21%), Positives = 64/147 (43%), Gaps = 10/147 (6%) Frame = +2 Query: 200 DGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTP--GESVLCGALAGA 373 +G + G A +LR P L+++ + +K+ ++ G AG Sbjct: 71 EGIVSFWRGNTANVLRYFPTQALNFAFKDKIKSLLSYDRERDGYAKWFAGNLFSGGAAGG 130 Query: 374 ISAGLTTPLDVVKTRLMTRVGAQGSRT--------VVGTMQEVIAEEGLMGLSRGIGPRV 529 +S LD +TRL A+GS++ ++ ++ + +GL+GL RG P V Sbjct: 131 LSLLFVYSLDYARTRLAA--DARGSKSTSQRQFNGLLDVYKKTLKTDGLLGLYRGFVPSV 188 Query: 530 LHSACFAAIGYCAFETARLMILKSYLE 610 L + + + +++ + ++L LE Sbjct: 189 LGIIVYRGLYFGLYDSFKPVLLTGALE 215
>ADT2_PONPY (Q5R5A1) ADP/ATP translocase 2 (Adenine nucleotide translocator 2)| (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) Length = 297 Score = 41.2 bits (95), Expect = 0.003 Identities = 35/147 (23%), Positives = 64/147 (43%), Gaps = 9/147 (6%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 358 +++I + G + G A ++R+ P L+++ + K L T G Sbjct: 57 VVRIPKEQGVLSFWRGNLANVIRHFPTQALNFAFKDKYKQIFLG--GVDKRTQFWRYFAG 114 Query: 359 ALAGAISAGLTT-----PLDVVKTRLMTRVGAQGS----RTVVGTMQEVIAEEGLMGLSR 511 LA +AG T+ PLD +TRL VG G+ R + + ++ +G+ GL + Sbjct: 115 NLASGGAAGATSLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQ 174 Query: 512 GIGPRVLHSACFAAIGYCAFETARLMI 592 G V + A + ++TA+ M+ Sbjct: 175 GFNVSVQGIIIYRAAYFGIYDTAKGML 201 Score = 39.3 bits (90), Expect = 0.010 Identities = 36/137 (26%), Positives = 67/137 (48%), Gaps = 9/137 (6%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 358 L++I ++DG GLY G+ ++ G++ Y + Y + +K P+ V+ Sbjct: 160 LVKIYKSDGIKGLYQGFNVSV-----QGIIIYRA-AYFGIYDTAKGMLPDPKNTHIVISW 213 Query: 359 ALAGAISA--GLTT-PLDVVKTRLMTRVGAQGSRTV-VGTM---QEVIAEEGLMGLSRGI 517 +A ++A GLT+ P D V+ R+M + G +G+ + GT+ +++ +EG +G Sbjct: 214 MIAQTVTAVAGLTSYPFDTVRRRMMMQSGRKGTDIMYTGTLDCWRKIARDEGGKAFFKGA 273 Query: 518 GPRVLH--SACFAAIGY 562 VL FA + Y Sbjct: 274 WSNVLRGMGGAFALVLY 290
>ADT3_HUMAN (P12236) ADP/ATP translocase 3 (Adenine nucleotide translocator 2)| (ANT 3) (ADP,ATP carrier protein 3) (Solute carrier family 25 member 6) (ADP,ATP carrier protein, isoform T2) Length = 297 Score = 40.8 bits (94), Expect = 0.003 Identities = 36/151 (23%), Positives = 64/151 (42%), Gaps = 13/151 (8%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSN---------APNL 331 +++I + G + G A ++R P L+++ + K L + A NL Sbjct: 57 IVRIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKHTQFWRYFAGNL 116 Query: 332 TPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGS----RTVVGTMQEVIAEEGLM 499 G + AGA S PLD +TRL VG G+ R + + ++ +G+ Sbjct: 117 ASGGA------AGATSLCFVYPLDFARTRLAADVGKSGTEREFRGLGDCLVKITKSDGIR 170 Query: 500 GLSRGIGPRVLHSACFAAIGYCAFETARLMI 592 GL +G V + A + ++TA+ M+ Sbjct: 171 GLYQGFSVSVQGIIIYRAAYFGVYDTAKGML 201 Score = 36.6 bits (83), Expect = 0.065 Identities = 29/125 (23%), Positives = 60/125 (48%), Gaps = 7/125 (5%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 358 L++I ++DG GLY G++ ++ G++ Y + Y + +K P+ V+ Sbjct: 160 LVKITKSDGIRGLYQGFSVSV-----QGIIIYRA-AYFGVYDTAKGMLPDPKNTHIVVSW 213 Query: 359 ALAGAISAG---LTTPLDVVKTRLMTRVGAQGSRTV----VGTMQEVIAEEGLMGLSRGI 517 +A ++A ++ P D V+ R+M + G +G+ + V +++ +EG +G Sbjct: 214 MIAQTVTAVAGVVSYPFDTVRRRMMMQSGRKGADIMYTGTVDCWRKIFRDEGGKAFFKGA 273 Query: 518 GPRVL 532 VL Sbjct: 274 WSNVL 278
>ADT2_HUMAN (P05141) ADP/ATP translocase 2 (Adenine nucleotide translocator 2)| (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) (ADP,ATP carrier protein, fibroblast isoform) Length = 297 Score = 40.0 bits (92), Expect = 0.006 Identities = 35/147 (23%), Positives = 63/147 (42%), Gaps = 9/147 (6%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 358 +++I + G + G A ++R P L+++ + K L T G Sbjct: 57 VVRIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLG--GVDKRTQFWRYFAG 114 Query: 359 ALAGAISAGLTT-----PLDVVKTRLMTRVGAQGS----RTVVGTMQEVIAEEGLMGLSR 511 LA +AG T+ PLD +TRL VG G+ R + + ++ +G+ GL + Sbjct: 115 NLASGGAAGATSLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQ 174 Query: 512 GIGPRVLHSACFAAIGYCAFETARLMI 592 G V + A + ++TA+ M+ Sbjct: 175 GFNVSVQGIIIYRAAYFGIYDTAKGML 201 Score = 38.5 bits (88), Expect = 0.017 Identities = 33/125 (26%), Positives = 63/125 (50%), Gaps = 7/125 (5%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 358 L++I ++DG GLY G+ ++ G++ Y + Y + +K P+ V+ Sbjct: 160 LVKIYKSDGIKGLYQGFNVSV-----QGIIIYRA-AYFGIYDTAKGMLPDPKNTHIVISW 213 Query: 359 ALAGAISA--GLTT-PLDVVKTRLMTRVGAQGSRTV-VGTM---QEVIAEEGLMGLSRGI 517 +A ++A GLT+ P D V+ R+M + G +G+ + GT+ +++ +EG +G Sbjct: 214 MIAQTVTAVAGLTSYPFDTVRRRMMMQSGRKGTDIMYTGTLDCWRKIARDEGGKAFFKGA 273 Query: 518 GPRVL 532 VL Sbjct: 274 WSNVL 278
>ADT2_BOVIN (Q8SQH5) ADP/ATP translocase 2 (Adenine nucleotide translocator 2)| (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) Length = 297 Score = 40.0 bits (92), Expect = 0.006 Identities = 35/147 (23%), Positives = 63/147 (42%), Gaps = 9/147 (6%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 358 +++I + G + G A ++R P L+++ + K L T G Sbjct: 57 VVRIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLG--GVDKRTQFWRYFAG 114 Query: 359 ALAGAISAGLTT-----PLDVVKTRLMTRVGAQGS----RTVVGTMQEVIAEEGLMGLSR 511 LA +AG T+ PLD +TRL VG G+ R + + ++ +G+ GL + Sbjct: 115 NLASGGAAGATSLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIRGLYQ 174 Query: 512 GIGPRVLHSACFAAIGYCAFETARLMI 592 G V + A + ++TA+ M+ Sbjct: 175 GFNVSVQGIIIYRAAYFGIYDTAKGML 201 Score = 38.1 bits (87), Expect = 0.022 Identities = 32/125 (25%), Positives = 63/125 (50%), Gaps = 7/125 (5%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 358 L++I ++DG GLY G+ ++ G++ Y + Y + +K P+ + Sbjct: 160 LVKIYKSDGIRGLYQGFNVSV-----QGIIIYRA-AYFGIYDTAKGMLPDPKNTHIFISW 213 Query: 359 ALAGAISA--GLTT-PLDVVKTRLMTRVGAQGSRTV-VGTM---QEVIAEEGLMGLSRGI 517 +A +++A GLT+ P D V+ R+M + G +G+ + GT+ +++ +EG +G Sbjct: 214 MIAQSVTAVAGLTSYPFDTVRRRMMMQSGRKGTDIMYTGTLDCWRKIARDEGAKAFFKGA 273 Query: 518 GPRVL 532 VL Sbjct: 274 WSNVL 278
>ADT1_HUMAN (P12235) ADP/ATP translocase 1 (Adenine nucleotide translocator 1)| (ANT 1) (ADP,ATP carrier protein 1) (Solute carrier family 25 member 4) (ADP,ATP carrier protein, heart/skeletal muscle isoform T1) Length = 297 Score = 39.7 bits (91), Expect = 0.008 Identities = 37/151 (24%), Positives = 64/151 (42%), Gaps = 13/151 (8%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSN---------APNL 331 +++I + GF + G A ++R P L+++ + K L + A NL Sbjct: 57 VVRIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNL 116 Query: 332 TPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAE----EGLM 499 G + AGA S PLD +TRL VG ++ + + I + +GL Sbjct: 117 ASGGA------AGATSLCFVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLR 170 Query: 500 GLSRGIGPRVLHSACFAAIGYCAFETARLMI 592 GL +G V + A + ++TA+ M+ Sbjct: 171 GLYQGFNVSVQGIIIYRAAYFGVYDTAKGML 201 Score = 35.4 bits (80), Expect = 0.15 Identities = 29/125 (23%), Positives = 60/125 (48%), Gaps = 7/125 (5%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 358 +++I ++DG GLY G+ ++ G++ Y + Y + +K P+ + Sbjct: 160 IIKIFKSDGLRGLYQGFNVSV-----QGIIIYRA-AYFGVYDTAKGMLPDPKNVHIFVSW 213 Query: 359 ALAGAISA--GLTT-PLDVVKTRLMTRVGAQGSRTV----VGTMQEVIAEEGLMGLSRGI 517 +A +++A GL + P D V+ R+M + G +G+ + V +++ +EG +G Sbjct: 214 MIAQSVTAVAGLVSYPFDTVRRRMMMQSGRKGADIMYTGTVDCWRKIAKDEGAKAFFKGA 273 Query: 518 GPRVL 532 VL Sbjct: 274 WSNVL 278
>ADT1_ARATH (P31167) ADP,ATP carrier protein 1, mitochondrial precursor| (ADP/ATP translocase 1) (Adenine nucleotide translocator 1) (ANT 1) Length = 381 Score = 39.7 bits (91), Expect = 0.008 Identities = 38/144 (26%), Positives = 64/144 (44%), Gaps = 12/144 (8%) Frame = +2 Query: 161 GRSWQVLLQI----LQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPN 328 GR + L+ + L+TDG GLY G+ + + G++ Y F L S P Sbjct: 226 GRQFDGLVDVYRKTLKTDGIAGLYRGFNISCV-----GIIVYRGL----YFGLYDSVKPV 276 Query: 329 LTPG---ESVLCGALAGAI---SAGLTT-PLDVVKTRLMTRVG-AQGSRTVVGTMQEVIA 484 L G +S G + AGL + P+D V+ R+M G A ++ + ++++ Sbjct: 277 LLTGDLQDSFFASFALGWVITNGAGLASYPIDTVRRRMMMTSGEAVKYKSSLDAFKQILK 336 Query: 485 EEGLMGLSRGIGPRVLHSACFAAI 556 EG L +G G +L + A + Sbjct: 337 NEGAKSLFKGAGANILRAVAGAGV 360 Score = 37.7 bits (86), Expect = 0.029 Identities = 32/149 (21%), Positives = 63/149 (42%), Gaps = 9/149 (6%) Frame = +2 Query: 191 LQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTP--GESVLCGAL 364 ++ +GF L+ G A ++R P L+++ +Y K K + ++ G Sbjct: 135 IKDEGFGSLWRGNTANVIRYFPTQALNFAFKDYFKRLFNFKKDRDGYWKWFAGNLASGGA 194 Query: 365 AGAISAGLTTPLDVVKTRLMTRVGAQ----GSRT---VVGTMQEVIAEEGLMGLSRGIGP 523 AGA S LD +TRL A G R +V ++ + +G+ GL RG Sbjct: 195 AGASSLLFVYSLDYARTRLANDAKAAKKGGGGRQFDGLVDVYRKTLKTDGIAGLYRGFNI 254 Query: 524 RVLHSACFAAIGYCAFETARLMILKSYLE 610 + + + + +++ + ++L L+ Sbjct: 255 SCVGIIVYRGLYFGLYDSVKPVLLTGDLQ 283
>ADT_NEUCR (P02723) ADP,ATP carrier protein (ADP/ATP translocase) (Adenine| nucleotide translocator) (ANT) Length = 313 Score = 39.7 bits (91), Expect = 0.008 Identities = 35/135 (25%), Positives = 61/135 (45%), Gaps = 8/135 (5%) Frame = +2 Query: 176 VLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGE---S 346 V + + +DG GLY G+ ++ AG++ Y F L S P L G+ + Sbjct: 167 VYRKTIASDGIAGLYRGFGPSV-----AGIVVYRGLY----FGLYDSIKPVLLVGDLKNN 217 Query: 347 VLCGALAG---AISAGLTT-PLDVVKTRLMTRVG-AQGSRTVVGTMQEVIAEEGLMGLSR 511 L G +AG+ + PLD ++ R+M G A ++ +++A+EG+ L + Sbjct: 218 FLASFALGWCVTTAAGIASYPLDTIRRRMMMTSGEAVKYKSSFDAASQIVAKEGVKSLFK 277 Query: 512 GIGPRVLHSACFAAI 556 G G +L A + Sbjct: 278 GAGANILRGVAGAGV 292
>ADT2_MAIZE (P12857) ADP,ATP carrier protein 2, mitochondrial precursor| (ADP/ATP translocase 2) (Adenine nucleotide translocator 2) (ANT 2) Length = 387 Score = 39.7 bits (91), Expect = 0.008 Identities = 34/129 (26%), Positives = 61/129 (47%), Gaps = 2/129 (1%) Frame = +2 Query: 176 VLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLC 355 V + L++DG GLY G+ + + + L + ++ +K L+ S N S Sbjct: 241 VYRKTLKSDGIAGLYRGFNISCVGIIVYRGLYFGLYDSIKPVVLTGSLQDNFFA--SFAL 298 Query: 356 GALAGAISAGLTT-PLDVVKTRLMTRVG-AQGSRTVVGTMQEVIAEEGLMGLSRGIGPRV 529 G L AGL + P+D V+ R+M G A ++ + Q+++ +EG L +G G + Sbjct: 299 GWLI-TNGAGLASYPIDTVRRRMMMTSGEAVKYKSSLDAFQQILKKEGPKSLFKGAGANI 357 Query: 530 LHSACFAAI 556 L + A + Sbjct: 358 LRAIAGAGV 366 Score = 39.7 bits (91), Expect = 0.008 Identities = 32/148 (21%), Positives = 63/148 (42%), Gaps = 8/148 (5%) Frame = +2 Query: 191 LQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTP--GESVLCGAL 364 ++ +GF L+ G A ++R P L+++ +Y K K + ++ G Sbjct: 142 IKDEGFSSLWRGNTANVIRYFPTQALNFAFKDYFKRLFNFKKDRDGYWKWFAGNLASGGA 201 Query: 365 AGAISAGLTTPLDVVKTRLMTRVGAQ---GSRT---VVGTMQEVIAEEGLMGLSRGIGPR 526 AGA S LD +TRL A G R +V ++ + +G+ GL RG Sbjct: 202 AGASSLFFVYSLDYARTRLANDAKAAKGGGDRQFNGLVDVYRKTLKSDGIAGLYRGFNIS 261 Query: 527 VLHSACFAAIGYCAFETARLMILKSYLE 610 + + + + +++ + ++L L+ Sbjct: 262 CVGIIVYRGLYFGLYDSIKPVVLTGSLQ 289
>ADT1_MAIZE (P04709) ADP,ATP carrier protein 1, mitochondrial precursor| (ADP/ATP translocase 1) (Adenine nucleotide translocator 1) (ANT 1) Length = 387 Score = 39.7 bits (91), Expect = 0.008 Identities = 30/148 (20%), Positives = 62/148 (41%), Gaps = 8/148 (5%) Frame = +2 Query: 191 LQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTP--GESVLCGAL 364 ++ +GF L+ G A ++R P L+++ +Y K K + ++ G Sbjct: 142 IKDEGFSSLWRGNTANVIRYFPTQALNFAFKDYFKRLFNFKKDRDGYWKWFAGNLASGGA 201 Query: 365 AGAISAGLTTPLDVVKTRLMTRV------GAQGSRTVVGTMQEVIAEEGLMGLSRGIGPR 526 AGA S LD +TRL G + +V ++ + +G+ GL RG Sbjct: 202 AGASSLFFVYSLDYARTRLANDAKAAKGGGERQFNGLVDVYRKTLKSDGIAGLYRGFNIS 261 Query: 527 VLHSACFAAIGYCAFETARLMILKSYLE 610 + + + + +++ + ++L L+ Sbjct: 262 CVGIIVYRGLYFGLYDSIKPVVLTGNLQ 289 Score = 38.5 bits (88), Expect = 0.017 Identities = 33/129 (25%), Positives = 61/129 (47%), Gaps = 2/129 (1%) Frame = +2 Query: 176 VLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLC 355 V + L++DG GLY G+ + + + L + ++ +K L+ + N S Sbjct: 241 VYRKTLKSDGIAGLYRGFNISCVGIIVYRGLYFGLYDSIKPVVLTGNLQDNFFA--SFAL 298 Query: 356 GALAGAISAGLTT-PLDVVKTRLMTRVG-AQGSRTVVGTMQEVIAEEGLMGLSRGIGPRV 529 G L AGL + P+D V+ R+M G A ++ + Q+++ +EG L +G G + Sbjct: 299 GWLI-TNGAGLASYPIDTVRRRMMMTSGEAVKYKSSLDAFQQILKKEGPKSLFKGAGANI 357 Query: 530 LHSACFAAI 556 L + A + Sbjct: 358 LRAIAGAGV 366
>ADT1_ANOGA (Q27238) ADP,ATP carrier protein 1 (ADP/ATP translocase 1) (Adenine| nucleotide translocator 1) (ANT 1) Length = 301 Score = 39.7 bits (91), Expect = 0.008 Identities = 38/145 (26%), Positives = 62/145 (42%), Gaps = 8/145 (5%) Frame = +2 Query: 182 LQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVL--- 352 ++I + G + G A ++R P L+++ + K L + N L Sbjct: 61 VRIPKEQGIGAFWRGNLANVIRYFPTQALNFAFKDVYKQVFLGGVDK-NTQFWRYFLGNL 119 Query: 353 -CGALAGAISAGLTTPLDVVKTRLMTRVG-AQGSRTVVG---TMQEVIAEEGLMGLSRGI 517 G AGA S PLD +TRL VG G R G +++ + +G++GL RG Sbjct: 120 GSGGAAGATSLCFVYPLDFARTRLGADVGRGAGEREFNGLLDCLKKTVKSDGIIGLYRGF 179 Query: 518 GPRVLHSACFAAIGYCAFETARLMI 592 V + A + F+TA+ M+ Sbjct: 180 NVSVQGIIIYRAAYFGCFDTAKGML 204 Score = 30.8 bits (68), Expect = 3.6 Identities = 22/96 (22%), Positives = 44/96 (45%), Gaps = 3/96 (3%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 358 L + +++DG GLY G+ ++ G++ Y + Y F +K P+ + Sbjct: 163 LKKTVKSDGIIGLYRGFNVSV-----QGIIIYRA-AYFGCFDTAKGMLPDPKNTSIFVSW 216 Query: 359 ALAGAISAG---LTTPLDVVKTRLMTRVGAQGSRTV 457 A+A ++ ++ P D V+ R+M + G S + Sbjct: 217 AIAQVVTTASGIISYPFDTVRRRMMMQSGRAKSEVM 252
>ADT1_SOLTU (P25083) ADP,ATP carrier protein, mitochondrial precursor (ADP/ATP| translocase) (Adenine nucleotide translocator) (ANT) Length = 386 Score = 39.3 bits (90), Expect = 0.010 Identities = 30/148 (20%), Positives = 63/148 (42%), Gaps = 8/148 (5%) Frame = +2 Query: 191 LQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTP--GESVLCGAL 364 ++ +GF L+ G A ++R P L+++ +Y K K + ++ G Sbjct: 141 IKEEGFGSLWRGNTANVIRYFPTQALNFAFKDYFKRLFNFKKDRDGYWKWFAGNLASGGA 200 Query: 365 AGAISAGLTTPLDVVKTRLMT------RVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPR 526 AGA S LD +TRL + G + +V ++ + +G+ GL RG Sbjct: 201 AGASSLFFVYSLDYARTRLANDRKASKKGGERQFNGLVDVYKKTLKSDGIAGLYRGFNIS 260 Query: 527 VLHSACFAAIGYCAFETARLMILKSYLE 610 + + + + +++ + ++L L+ Sbjct: 261 CVGIIVYRGLYFGMYDSLKPVLLTGNLQ 288 Score = 35.4 bits (80), Expect = 0.15 Identities = 35/144 (24%), Positives = 67/144 (46%), Gaps = 4/144 (2%) Frame = +2 Query: 176 VLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLC 355 V + L++DG GLY G+ + + + L + ++ LK L+ NL Sbjct: 240 VYKKTLKSDGIAGLYRGFNISCVGIIVYRGLYFGMYDSLKPVLLT----GNLQDSFFASF 295 Query: 356 GALAGAIS--AGLTT-PLDVVKTRLMTRVG-AQGSRTVVGTMQEVIAEEGLMGLSRGIGP 523 G L I+ AGL + P+D V+ R+M G A ++ + +++ EG L +G G Sbjct: 296 G-LGWLITNGAGLASYPIDTVRRRMMMTSGEAVKYKSSLDAFSQIVKNEGPKSLFKGAGA 354 Query: 524 RVLHSACFAAIGYCAFETARLMIL 595 +L + A + ++ ++++L Sbjct: 355 NILRAVAGAGV-LAGYDKLQVLVL 377
>ADT2_RAT (Q09073) ADP/ATP translocase 2 (Adenine nucleotide translocator 2)| (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) Length = 297 Score = 38.9 bits (89), Expect = 0.013 Identities = 34/147 (23%), Positives = 63/147 (42%), Gaps = 9/147 (6%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 358 +++I + G + G A ++R P L+++ + K L T G Sbjct: 57 VVRIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLG--GVDKRTQFWRYFAG 114 Query: 359 ALAGAISAGLTT-----PLDVVKTRLMTRVGAQGS----RTVVGTMQEVIAEEGLMGLSR 511 LA +AG T+ PLD +TRL VG G+ + + + ++ +G+ GL + Sbjct: 115 NLASGGAAGATSLCFVYPLDFARTRLAADVGKAGAEREFKGLGDCLVKIYKSDGIKGLYQ 174 Query: 512 GIGPRVLHSACFAAIGYCAFETARLMI 592 G V + A + ++TA+ M+ Sbjct: 175 GFNVSVQGIIIYRAAYFGIYDTAKGML 201 Score = 37.0 bits (84), Expect = 0.050 Identities = 32/125 (25%), Positives = 63/125 (50%), Gaps = 7/125 (5%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 358 L++I ++DG GLY G+ ++ G++ Y + Y + +K P+ + Sbjct: 160 LVKIYKSDGIKGLYQGFNVSV-----QGIIIYRA-AYFGIYDTAKGMLPDPKNTHIFISW 213 Query: 359 ALAGAISA--GLTT-PLDVVKTRLMTRVGAQGSRTV-VGTM---QEVIAEEGLMGLSRGI 517 +A +++A GLT+ P D V+ R+M + G +G+ + GT+ +++ +EG +G Sbjct: 214 MIAQSVTAVAGLTSYPFDTVRRRMMMQSGRKGTDIMYTGTLDCWRKIARDEGGKAFFKGA 273 Query: 518 GPRVL 532 VL Sbjct: 274 WSNVL 278
>ADT2_MOUSE (P51881) ADP/ATP translocase 2 (Adenine nucleotide translocator 2)| (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) Length = 297 Score = 38.9 bits (89), Expect = 0.013 Identities = 34/147 (23%), Positives = 63/147 (42%), Gaps = 9/147 (6%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 358 +++I + G + G A ++R P L+++ + K L T G Sbjct: 57 VVRIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLG--GVDKRTQFWRYFAG 114 Query: 359 ALAGAISAGLTT-----PLDVVKTRLMTRVGAQGS----RTVVGTMQEVIAEEGLMGLSR 511 LA +AG T+ PLD +TRL VG G+ + + + ++ +G+ GL + Sbjct: 115 NLASGGAAGATSLCFVYPLDFARTRLAADVGKAGAEREFKGLGDCLVKIYKSDGIKGLYQ 174 Query: 512 GIGPRVLHSACFAAIGYCAFETARLMI 592 G V + A + ++TA+ M+ Sbjct: 175 GFNVSVQGIIIYRAAYFGIYDTAKGML 201 Score = 37.7 bits (86), Expect = 0.029 Identities = 32/125 (25%), Positives = 63/125 (50%), Gaps = 7/125 (5%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 358 L++I ++DG GLY G+ ++ G++ Y + Y + +K P+ + Sbjct: 160 LVKIYKSDGIKGLYQGFNVSV-----QGIIIYRA-AYFGIYDTAKGMLPDPKNTHIFISW 213 Query: 359 ALAGAISA--GLTT-PLDVVKTRLMTRVGAQGSRTV-VGTM---QEVIAEEGLMGLSRGI 517 +A +++A GLT+ P D V+ R+M + G +G+ + GT+ +++ +EG +G Sbjct: 214 MIAQSVTAVAGLTSYPFDTVRRRMMMQSGRKGTDIMYTGTLDCWRKIARDEGSKAFFKGA 273 Query: 518 GPRVL 532 VL Sbjct: 274 WSNVL 278
>PIC2_YEAST (P40035) Mitochondrial phosphate carrier protein 2 (Phosphate| transport protein 2) (PTP 2) (mPic 2) (Pi carrier isoform 2) Length = 300 Score = 38.1 bits (87), Expect = 0.022 Identities = 36/158 (22%), Positives = 64/158 (40%), Gaps = 3/158 (1%) Frame = +2 Query: 110 MVPKELITQRLQSGAATGRS-WQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFE 286 + P +L+ RLQ S Q +I+ +G+ +Y G+ AT + G Y +E Sbjct: 36 ITPLDLVKCRLQVNPKLYTSNLQGFRKIIANEGWKKVYTGFGATFVGYSLQGAGKYGGYE 95 Query: 287 YLKAFALSKSNAPNLTPGESV--LCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVV 460 Y K S L+PG +V + A A ++ + P + +K + T + + V Sbjct: 96 YFKHLYSSW-----LSPGVTVYLMASATAEFLADIMLCPFEAIKVKQQTTMPPFCNNVVD 150 Query: 461 GTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFE 574 G + G+ +GI P + + +FE Sbjct: 151 GWKKMYAESGGMKAFYKGIVPLWCRQIPYTMCKFTSFE 188 Score = 33.1 bits (74), Expect = 0.72 Identities = 25/139 (17%), Positives = 61/139 (43%), Gaps = 6/139 (4%) Frame = +2 Query: 194 QTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYL--KAFALSKSNAPNLTPGESV----LC 355 ++ G Y G R +P + ++SFE + K +++ + + + + Sbjct: 158 ESGGMKAFYKGIVPLWCRQIPYTMCKFTSFEKIVQKIYSVLPKKKEEMNALQQISVSFVG 217 Query: 356 GALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLH 535 G LAG + A ++ P DV+ +++ + A S +V + + + G GL G+ R++ Sbjct: 218 GYLAGILCAAVSHPADVMVSKINSERKANESMSVAS--KRIYQKIGFTGLWNGLMVRIVM 275 Query: 536 SACFAAIGYCAFETARLMI 592 + + +++ + + Sbjct: 276 IGTLTSFQWLIYDSFKAYV 294
>UCP1_MOUSE (P12242) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 306 Score = 38.1 bits (87), Expect = 0.022 Identities = 31/138 (22%), Positives = 58/138 (42%) Frame = +2 Query: 188 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 367 I T+ L+ G L+RN+ +++ +K ++ + P +L +A Sbjct: 163 IATTESLSTLWKGTTPNLMRNVIINCTELVTYDLMKGALVNNKILADDVPCH-LLSALVA 221 Query: 368 GAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACF 547 G + L +P+DVVKTR + + Q +V + +EG +G L + Sbjct: 222 GFCTTLLASPVDVVKTRFINSLPGQ-YPSVPSCAMSMYTKEGPTAFFKGFVASFLRLGSW 280 Query: 548 AAIGYCAFETARLMILKS 601 I + FE + ++KS Sbjct: 281 NVIMFVCFEQLKKELMKS 298
>ADT1_GOSHI (O22342) ADP,ATP carrier protein 1, mitochondrial precursor| (ADP/ATP translocase 1) (Adenine nucleotide translocator 1) (ANT 1) Length = 386 Score = 38.1 bits (87), Expect = 0.022 Identities = 31/128 (24%), Positives = 59/128 (46%), Gaps = 1/128 (0%) Frame = +2 Query: 176 VLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLC 355 V + L++DG GLY G+ + + + L + ++ LK L+ S + S + Sbjct: 240 VYRKTLKSDGIAGLYRGFNISCVGIIVYRGLYFGMYDSLKPVLLTGSMQDSFF--ASFVL 297 Query: 356 GALAGAISAGLTTPLDVVKTRLMTRVG-AQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVL 532 G L +A + P+D V+ R+M G A ++ + +++ EG L +G G +L Sbjct: 298 GWLITNGAALASYPIDTVRRRMMMTSGKAVKYKSSLDAFSQILKNEGGKSLFKGAGSNIL 357 Query: 533 HSACFAAI 556 + A + Sbjct: 358 RAIAGAGV 365 Score = 38.1 bits (87), Expect = 0.022 Identities = 29/148 (19%), Positives = 63/148 (42%), Gaps = 8/148 (5%) Frame = +2 Query: 191 LQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTP--GESVLCGAL 364 ++ +GF L+ G A ++R P L+++ +Y K K + ++ G Sbjct: 141 IKDEGFGSLWRGNTANVIRYFPTQALNFAFKDYFKRLFNFKKDRDGYWKWFAGNLASGGA 200 Query: 365 AGAISAGLTTPLDVVKTRLMT------RVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPR 526 AGA S LD +TRL + G + +V ++ + +G+ GL RG Sbjct: 201 AGASSLLFVYSLDYARTRLANDAKAAKKGGERQFNGLVDVYRKTLKSDGIAGLYRGFNIS 260 Query: 527 VLHSACFAAIGYCAFETARLMILKSYLE 610 + + + + +++ + ++L ++ Sbjct: 261 CVGIIVYRGLYFGMYDSLKPVLLTGSMQ 288
>ADT2_ARATH (P40941) ADP,ATP carrier protein 2, mitochondrial precursor| (ADP/ATP translocase 2) (Adenine nucleotide translocator 2) (ANT 2) Length = 385 Score = 38.1 bits (87), Expect = 0.022 Identities = 36/135 (26%), Positives = 59/135 (43%), Gaps = 8/135 (5%) Frame = +2 Query: 176 VLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGE---S 346 V + L++DG GLY G+ + AG++ Y F L S P L G+ S Sbjct: 239 VYKKTLKSDGIAGLYRGFNISC-----AGIIVYRGLY----FGLYDSVKPVLLTGDLQDS 289 Query: 347 VLCGALAGAI---SAGLTT-PLDVVKTRLMTRVG-AQGSRTVVGTMQEVIAEEGLMGLSR 511 G + AGL + P+D V+ R+M G A ++ +++ +EG L + Sbjct: 290 FFASFALGWLITNGAGLASYPIDTVRRRMMMTSGEAVKYKSSFDAFSQIVKKEGAKSLFK 349 Query: 512 GIGPRVLHSACFAAI 556 G G +L + A + Sbjct: 350 GAGANILRAVAGAGV 364
>MFN2B_XENLA (Q68F18) Mitoferrin-2B (Mitochondrial iron transporter 2-B) (Solute| carrier family 25 member 28-B) Length = 186 Score = 37.7 bits (86), Expect = 0.029 Identities = 35/113 (30%), Positives = 53/113 (46%), Gaps = 17/113 (15%) Frame = +2 Query: 260 GVLSYSSFEYLKAFALSKSNAPN---LTPGESV----LCGALAGAISAGLTTPLDVVKTR 418 G L++ S + L+ N P L G +V L GA+AG + L P+D VKTR Sbjct: 45 GTLAFESTSSSRILELTSDNDPEYEALPEGSNVTAHMLAGAVAGVMEHCLMYPVDCVKTR 104 Query: 419 LMTRV--GAQGSRTVVGTMQEVIAEEG----LMGL---SRGIGP-RVLHSACF 547 + + A R V+ + +++ EG L GL + G GP L+ AC+ Sbjct: 105 MQSLQPDPAARYRNVMDALSKIVRTEGFWRPLRGLNVTATGAGPAHALYFACY 157
>CMC1_YEAST (P48233) Calcium-binding mitochondrial carrier SAL1 (Suppressor of| AAC2 lethality) Length = 545 Score = 37.7 bits (86), Expect = 0.029 Identities = 23/68 (33%), Positives = 34/68 (50%), Gaps = 6/68 (8%) Frame = +2 Query: 116 PKELITQRLQSGAATGRSW------QVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYS 277 P L+ RLQ+ + VLL+ L+ +G+ GL+ G TL + PA +SY Sbjct: 474 PINLLRTRLQAQGTYAHPYVYNGFKDVLLKTLEREGYQGLFKGLVPTLAKVCPAVSISYL 533 Query: 278 SFEYLKAF 301 +E LK F Sbjct: 534 CYENLKKF 541 Score = 35.4 bits (80), Expect = 0.15 Identities = 27/133 (20%), Positives = 53/133 (39%), Gaps = 6/133 (4%) Frame = +2 Query: 203 GFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKS---NAPNLTPGESVLCGALAGA 373 G Y G +++ P + + SFE K + +L+ + + G LAG Sbjct: 300 GIKAFYVGNGLNVIKVFPESSIKFGSFEVTKKIMTKLEGCRDTKDLSKFSTYIAGGLAGM 359 Query: 374 ISAGLTTPLDVVKTRLMTR---VGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSAC 544 + P+D +K R+ +G+ + T +++ E GL RG+ ++ Sbjct: 360 AAQFSVYPIDTLKFRVQCAPLDTKLKGNNLLFQTAKDMFREGGLRLFYRGVTVGIVGIFP 419 Query: 545 FAAIGYCAFETAR 583 +AA+ F + Sbjct: 420 YAALDLGTFSALK 432
>ADT2_SOLTU (P27081) ADP,ATP carrier protein, mitochondrial precursor (ADP/ATP| translocase) (Adenine nucleotide translocator) (ANT) (Fragment) Length = 386 Score = 37.4 bits (85), Expect = 0.038 Identities = 32/149 (21%), Positives = 63/149 (42%), Gaps = 9/149 (6%) Frame = +2 Query: 191 LQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTP--GESVLCGAL 364 ++ +GF L+ G A ++R P L+++ +Y K K + ++ G Sbjct: 140 IKDEGFAALWRGNTANVIRYFPTQALNFAFKDYFKRLFNFKKDRDGYWKWFAGNLASGGG 199 Query: 365 AGAISAGLTTPLDVVKTRLMTRVGAQ----GSRT---VVGTMQEVIAEEGLMGLSRGIGP 523 AGA S LD +TRL A G R +V ++ + +G+ GL RG Sbjct: 200 AGASSLLFVYSLDYARTRLANDAKAAKKGGGGRQFDGLVDVYRKTLKSDGVAGLYRGFNI 259 Query: 524 RVLHSACFAAIGYCAFETARLMILKSYLE 610 + + + + +++ + ++L +E Sbjct: 260 SCVGIIVYRGLYFGMYDSLKPVLLTGKME 288 Score = 35.0 bits (79), Expect = 0.19 Identities = 35/138 (25%), Positives = 61/138 (44%), Gaps = 6/138 (4%) Frame = +2 Query: 161 GRSWQVLLQI----LQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPN 328 GR + L+ + L++DG GLY G+ + + + L + ++ LK L+ + Sbjct: 231 GRQFDGLVDVYRKTLKSDGVAGLYRGFNISCVGIIVYRGLYFGMYDSLKPVLLTGKMEDS 290 Query: 329 LTPGESVLCGALAGAISAGLTT-PLDVVKTRLMTRVG-AQGSRTVVGTMQEVIAEEGLMG 502 S G L AGL + P+D V+ R+M G A ++ +++ EG Sbjct: 291 FF--ASFALGWLI-TNGAGLASYPIDTVRRRMMMTSGEAVKYKSSFDAFNQILKNEGPKS 347 Query: 503 LSRGIGPRVLHSACFAAI 556 L +G G VL + A + Sbjct: 348 LFKGAGANVLRAVAGAGV 365
>DIC1_YEAST (Q06143) Mitochondrial dicarboxylate transporter (Dicarboxylate| carrier 1) (DTP) Length = 298 Score = 36.2 bits (82), Expect = 0.085 Identities = 25/124 (20%), Positives = 54/124 (43%) Frame = +2 Query: 203 GFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISA 382 G L+ G+ ++R + +++ K + ++K + + LAG ++ Sbjct: 163 GLKTLFTGWKPNMVRGILMTASQVVTYDVFKNYLVTKLDFDASKNYTHLTASLLAGLVAT 222 Query: 383 GLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGY 562 + +P DV+KTR+M G+ + + + + + +EG + RG P F + + Sbjct: 223 TVCSPADVMKTRIMN--GSGDHQPALKILADAVRKEGPSFMFRGWLPSFTRLGPFTMLIF 280 Query: 563 CAFE 574 A E Sbjct: 281 FAIE 284
>ADT3_PIG (Q6QRN9) ADP/ATP translocase 3 (Adenine nucleotide translocator 2)| (ANT 3) (ADP,ATP carrier protein 3) (Solute carrier family 25 member 6) Length = 297 Score = 35.8 bits (81), Expect = 0.11 Identities = 30/125 (24%), Positives = 60/125 (48%), Gaps = 7/125 (5%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 358 L++I ++DG GLY G+ ++ G++ Y + Y + +K P+ V+ Sbjct: 160 LVKITKSDGIRGLYQGFNVSV-----QGIIIYRA-AYFGVYGTAKGMLPDPRNTHIVVSW 213 Query: 359 ALAGAISAG---LTTPLDVVKTRLMTRVGAQGSRTVV-GTM---QEVIAEEGLMGLSRGI 517 +A ++A + P D V+ R+M + G +G+ + GT+ +++ +EG +G Sbjct: 214 MIAQTVTAVAGVFSYPFDTVRRRMMMQSGRKGADIMYKGTLDCWRKIFKDEGGKAFFKGA 273 Query: 518 GPRVL 532 VL Sbjct: 274 WSNVL 278 Score = 35.8 bits (81), Expect = 0.11 Identities = 34/151 (22%), Positives = 62/151 (41%), Gaps = 13/151 (8%) Frame = +2 Query: 179 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSN---------APNL 331 +++I + G + G A ++R P L+++ + K L + A NL Sbjct: 57 IVRIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKHTQFWRYFAGNL 116 Query: 332 TPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGS----RTVVGTMQEVIAEEGLM 499 G + AGA S PLD +TRL VG + + + + ++ +G+ Sbjct: 117 ASGGA------AGATSLCFVYPLDFARTRLAADVGKSATEREFKGLGDCLVKITKSDGIR 170 Query: 500 GLSRGIGPRVLHSACFAAIGYCAFETARLMI 592 GL +G V + A + + TA+ M+ Sbjct: 171 GLYQGFNVSVQGIIIYRAAYFGVYGTAKGML 201
>MFN2A_XENLA (Q6GLJ0) Mitoferrin-2A (Mitochondrial iron transporter 2-A) (Solute| carrier family 25 member 28-A) Length = 186 Score = 35.4 bits (80), Expect = 0.15 Identities = 36/113 (31%), Positives = 52/113 (46%), Gaps = 17/113 (15%) Frame = +2 Query: 260 GVLSYSSFEYLKAFALSKSNAPN---LTPGESV----LCGALAGAISAGLTTPLDVVKTR 418 G L++ S SK N P L G +V L GA+AG + L P+D VKTR Sbjct: 45 GPLAFESTSSRILELASKDNEPEYEALPDGSNVTTHMLAGAVAGVMEHCLMYPVDCVKTR 104 Query: 419 LMTRV--GAQGSRTVVGTMQEVIAEEG----LMGL---SRGIGP-RVLHSACF 547 + + A R V+ + +++ EG L GL + G GP L+ AC+ Sbjct: 105 MQSLQPDPAARYRNVMDALSKIVRTEGFWRPLRGLNVTATGAGPAHALYFACY 157
>MCAR1_HUMAN (Q9H1U9) Mitochondrial carrier triple repeat 1| Length = 297 Score = 35.0 bits (79), Expect = 0.19 Identities = 24/84 (28%), Positives = 39/84 (46%) Frame = +2 Query: 191 LQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAG 370 L+ G Y G L RN + VL + +K L + + +CG L G Sbjct: 164 LKCHGIGEYYRGLVPILFRNGLSNVLFFGLRGPIKEH-LPTATTHSAHLVNDFICGGLLG 222 Query: 371 AISAGLTTPLDVVKTRLMTRVGAQ 442 A+ L P++VVKTR+ +++G + Sbjct: 223 AMLGFLFFPINVVKTRIQSQIGGE 246 Score = 31.6 bits (70), Expect = 2.1 Identities = 24/77 (31%), Positives = 34/77 (44%) Frame = +2 Query: 191 LQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAG 370 L+ DGF LY G L++ L + +E L +AP S + LAG Sbjct: 72 LRRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLLHKHVSAPEF--ATSGVAAVLAG 129 Query: 371 AISAGLTTPLDVVKTRL 421 A + TPL+ V+T L Sbjct: 130 TTEA-IFTPLERVQTLL 145
>MTCH1_MOUSE (Q791T5) Mitochondrial carrier homolog 1 (Mitochondrial| carrier-like protein 1) Length = 389 Score = 34.7 bits (78), Expect = 0.25 Identities = 32/128 (25%), Positives = 57/128 (44%), Gaps = 8/128 (6%) Frame = +2 Query: 188 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSK-SNAPNLTPG-----ESV 349 I+Q DG GL+ G + L+ N + V S + + + SN ++ + Sbjct: 139 IVQVDGKIGLFRGLSPRLMSNALSTVTRGSMKKVFPPDEMEQVSNKDDMKTSLKKVVKET 198 Query: 350 LCGALAGAISAGLTTPLDVVKTRLMTR-VGAQGSRT-VVGTMQEVIAEEGLMGLSRGIGP 523 + +S L PL V+ R M + VG + + V+ ++ ++ EEGL+G G+ P Sbjct: 199 SYEMMMQCVSRMLAHPLHVISMRCMVQFVGREAKYSGVLSSIGKIFKEEGLLGFFVGLIP 258 Query: 524 RVLHSACF 547 +L F Sbjct: 259 HLLGDVVF 266
>MTCH1_HUMAN (Q9NZJ7) Mitochondrial carrier homolog 1 (Presenilin-associated| protein) Length = 389 Score = 34.7 bits (78), Expect = 0.25 Identities = 32/128 (25%), Positives = 57/128 (44%), Gaps = 8/128 (6%) Frame = +2 Query: 188 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSK-SNAPNLTPG-----ESV 349 I+Q DG GL+ G + L+ N + V S + + + SN ++ + Sbjct: 139 IVQVDGKIGLFRGLSPRLMSNALSTVTRGSMKKVFPPDEIEQVSNKDDMKTSLKKVVKET 198 Query: 350 LCGALAGAISAGLTTPLDVVKTRLMTR-VGAQGSRT-VVGTMQEVIAEEGLMGLSRGIGP 523 + +S L PL V+ R M + VG + + V+ ++ ++ EEGL+G G+ P Sbjct: 199 SYEMMMQCVSRMLAHPLHVISMRCMVQFVGREAKYSGVLSSIGKIFKEEGLLGFFVGLIP 258 Query: 524 RVLHSACF 547 +L F Sbjct: 259 HLLGDVVF 266
>ANT1_YEAST (Q06497) Peroxisomal adenine nucleotide transporter 1| Length = 328 Score = 34.3 bits (77), Expect = 0.32 Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 14/73 (19%) Frame = +2 Query: 341 ESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGS--------------RTVVGTMQEV 478 ES L GA+A A++ PLD+ KT + ++V S + VV M + Sbjct: 5 ESALTGAVASAMANIAVYPLDLSKTIIQSQVSPSSSEDSNEGKVLPNRRYKNVVDCMINI 64 Query: 479 IAEEGLMGLSRGI 517 E+G++GL +G+ Sbjct: 65 FKEKGILGLYQGM 77
>MPCP_CHOFU (O61703) Phosphate carrier protein, mitochondrial precursor| (Phosphate transport protein) (PTP) Length = 349 Score = 34.3 bits (77), Expect = 0.32 Identities = 25/124 (20%), Positives = 57/124 (45%), Gaps = 8/124 (6%) Frame = +2 Query: 245 RNLPAGVLSYSSFE----YLKAFALSKSNAPNLTPGESVL----CGALAGAISAGLTTPL 400 R +P ++ ++ FE L + K A + GE ++ G +AG A ++ P Sbjct: 211 RQIPYTMMKFACFEKTVELLYKHVVPKPRA-ECSKGEQLVVTFAAGYIAGVFCAIVSHPA 269 Query: 401 DVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETA 580 D V ++L ++ T+ ++ + G G+ +G+GPR++ A+ + ++ Sbjct: 270 DTVVSKL--------NQDKTATVGSIVGKLGFAGVWKGLGPRIIMIGTLTALQWFIYDAV 321 Query: 581 RLMI 592 ++ + Sbjct: 322 KVWL 325
>MCAR1_MOUSE (Q5HZI9) Mitochondrial carrier triple repeat 1| Length = 298 Score = 33.1 bits (74), Expect = 0.72 Identities = 22/82 (26%), Positives = 38/82 (46%) Frame = +2 Query: 191 LQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAG 370 L+ G Y G L RN VL + +K +L + + +CG + G Sbjct: 165 LRCHGIAEYYRGMVPILFRNGFGNVLFFGLRGPIKE-SLPTATTYSAHLVNDFICGGVLG 223 Query: 371 AISAGLTTPLDVVKTRLMTRVG 436 A+ L+ P++VVK R+ +++G Sbjct: 224 AVLGFLSFPINVVKARIQSQIG 245
>VE4_HPV05 (P06924) Probable protein E4| Length = 245 Score = 32.0 bits (71), Expect = 1.6 Identities = 23/74 (31%), Positives = 28/74 (37%), Gaps = 7/74 (9%) Frame = -1 Query: 538 AVQDPRSDPPGQAH---QAFLGDDLLHRAHDRAAPLGAHPGHQPRLDDVE----RGGEPR 380 A +DP P A + G D H AP H GH+P++ E R G Sbjct: 121 ADRDPEEGPQPPAEGEVEGHPGGDQGHPPPPPPAPHNGHSGHEPKVQQPEGPEGREGHEE 180 Query: 379 GYRAGEGAAEHALP 338 G GEG E P Sbjct: 181 GAVGGEGGDEEGHP 194
>MFRN1_BOVIN (Q3ZBJ8) Mitoferrin-1 (Mitochondrial iron transporter 1) (Solute| carrier family 25 member 37) Length = 171 Score = 31.6 bits (70), Expect = 2.1 Identities = 19/78 (24%), Positives = 39/78 (50%), Gaps = 2/78 (2%) Frame = +2 Query: 356 GALAGAISAGLTTPLDVVKTRLMTRVGAQGSR--TVVGTMQEVIAEEGLMGLSRGIGPRV 529 GA+AG + + P+D VKTR+ + + +V G ++++I EG RG+ + Sbjct: 52 GAMAGILEHSVMYPVDSVKTRMQSLNPDPKAHYTSVYGALKKIIRTEGFWRPLRGLNVMM 111 Query: 530 LHSACFAAIGYCAFETAR 583 + + A+ + +E + Sbjct: 112 MGAGPAHAMYFACYENMK 129
>YD1K_SCHPO (Q10248) Putative mitochondrial carrier C4G9.20c| Length = 302 Score = 31.6 bits (70), Expect = 2.1 Identities = 17/59 (28%), Positives = 26/59 (44%) Frame = +2 Query: 110 MVPKELITQRLQSGAATGRSWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFE 286 +V ++ T S A SWQ I G G Y G+ L+R PA +++ +E Sbjct: 235 IVKSKIQTDGFLSKATYKNSWQCAKGIYTKAGLRGFYRGFVPVLVRAAPANAVTFYVYE 293
>PPX_SALTY (P0A269) Exopolyphosphatase (EC 3.6.1.11) (ExopolyPase)| (Metaphosphatase) Length = 512 Score = 30.0 bits (66), Expect = 6.1 Identities = 20/62 (32%), Positives = 28/62 (45%) Frame = +2 Query: 173 QVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVL 352 +VLL + + DGF L L + VL + SF L LS+ PG ++L Sbjct: 224 EVLLALGEKDGFI------TPERLDKLKSEVLKHRSFNALSLPGLSEERKAVFVPGLAIL 277 Query: 353 CG 358 CG Sbjct: 278 CG 279
>PPX_SALTI (P0A270) Exopolyphosphatase (EC 3.6.1.11) (ExopolyPase)| (Metaphosphatase) Length = 512 Score = 30.0 bits (66), Expect = 6.1 Identities = 20/62 (32%), Positives = 28/62 (45%) Frame = +2 Query: 173 QVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVL 352 +VLL + + DGF L L + VL + SF L LS+ PG ++L Sbjct: 224 EVLLALGEKDGFI------TPERLDKLKSEVLKHRSFNALSLPGLSEERKAVFVPGLAIL 277 Query: 353 CG 358 CG Sbjct: 278 CG 279
>MUCDL_HUMAN (Q9HBB8) Mucin and cadherin-like protein precursor| (Mu-protocadherin) Length = 845 Score = 29.6 bits (65), Expect = 8.0 Identities = 23/74 (31%), Positives = 31/74 (41%) Frame = -1 Query: 604 VRLEDHEPGRLKCAVANRSEACAVQDPRSDPPGQAHQAFLGDDLLHRAHDRAAPLGAHPG 425 V + H RLKC C+ + P P G +QAFL D H+A+ P P Sbjct: 688 VLVHKHYGPRLKC--------CSGKAPEPQPQGFDNQAFLPD---HKANWAPVP---SPT 733 Query: 424 HQPRLDDVERGGEP 383 H P+ + EP Sbjct: 734 HDPKPAEAPMPAEP 747
>MTG8_MOUSE (Q61909) Protein CBFA2T1 (MTG8 protein)| Length = 577 Score = 29.6 bits (65), Expect = 8.0 Identities = 16/33 (48%), Positives = 20/33 (60%) Frame = -2 Query: 432 TLVISRVLTTSSGVVSPADIAPARAPQSTLSPG 334 T +S +T SSG SP D PA P+ST +PG Sbjct: 536 TPAVSSSVTPSSGAGSPMDTPPAATPRST-TPG 567
>R1AB_CVPPU (Q9IW06) Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein)| [Includes: Replicase polyprotein 1a (pp1a) (ORF1a)] [Contains: p9; p87; p195 (EC 3.4.22.-) (Papain-like proteinases 1/2) (PL1-PRO/PL2-PRO); Peptide HD2; Unknown protein 1; 3C-like Length = 6684 Score = 29.6 bits (65), Expect = 8.0 Identities = 35/158 (22%), Positives = 62/158 (39%), Gaps = 2/158 (1%) Frame = +2 Query: 113 VPKELITQRLQSGAATGRSWQVLLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYL 292 + ++L Q+ AT RS Q + ++ +DGF+ Y G T + YSS E L Sbjct: 2118 IVRDLSNSVKQTVYATDRSHQEVTKVECSDGFYRFYVGDEFTSY-DYDVKHKKYSSQEVL 2176 Query: 293 KAFALSKSNAPNLTPGESVLCGALAGAI--SAGLTTPLDVVKTRLMTRVGAQGSRTVVGT 466 K+ L + +P S L + S + P+ +V + L+ + + Sbjct: 2177 KSMLL-LDDFIVYSPSGSALANVRNACVYFSQLIGKPIKIVNSDLLEDLSVDFKGALFNA 2235 Query: 467 MQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETA 580 + VI + +S + AC + + FE A Sbjct: 2236 KKNVIKNSFNVDVSECKNLDECYRACNLNVSFSTFEMA 2273
>FTSK_PSEPK (Q88FS8) DNA translocase ftsK| Length = 834 Score = 29.6 bits (65), Expect = 8.0 Identities = 19/59 (32%), Positives = 27/59 (45%) Frame = -1 Query: 526 PRSDPPGQAHQAFLGDDLLHRAHDRAAPLGAHPGHQPRLDDVERGGEPRGYRAGEGAAE 350 P + P + H AF+ DD +HR + GA + L+ VE G G+ G G E Sbjct: 707 PGTSLPIRVHGAFVSDDEVHRTVEAWKLRGAPDYNDDILNGVEEAGS--GFDGGGGGGE 763 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 56,728,488 Number of Sequences: 219361 Number of extensions: 1044682 Number of successful extensions: 4438 Number of sequences better than 10.0: 183 Number of HSP's better than 10.0 without gapping: 3919 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4284 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 6029593548 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
