>ANR12_HUMAN (Q6UB98) Ankyrin repeat domain-containing protein 12 (Ankyrin|
            repeat-containing cofactor 2) (GAC-1 protein)
          Length = 2062

 Score = 37.0 bits (84), Expect = 0.041
 Identities = 20/77 (25%), Positives = 42/77 (54%), Gaps = 3/77 (3%)
 Frame = +2

Query: 338  KHIQSSKENHGTVSRKNNEG---QFSKEVQQSASEKNGGADSGEVASDKENVNCDVNHEE 508
            +H+  SKE H  + +KN +    ++SK  +    EK+   D  E + DKE++N   N + 
Sbjct: 920  RHLAESKEKH-LMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKEKSRDKESINI-TNSKH 977

Query: 509  VRQHQRTNASGGRKGRY 559
            +++ ++++   G K ++
Sbjct: 978  IQEEKKSSIVDGNKAQH 994

>GLE1_BRARE (Q6DRB1) Nucleoporin GLE1 (GLE1-like protein)|
          Length = 695

 Score = 32.3 bits (72), Expect = 1.0
 Identities = 17/47 (36%), Positives = 26/47 (55%)
 Frame = +3

Query: 342 ISSLRKKIMEQFRERTTRASFQKKYNSRHRKKMVVLIQERLLQIRRM 482
           I +LR + MEQ R R      Q++   R R + +  IQE +LQ+ R+
Sbjct: 238 ILNLRLREMEQQRLREVELERQRQVEGRERHRAINAIQEEVLQLNRL 284

>IF2_LACPL (Q88VK7) Translation initiation factor IF-2|
          Length = 858

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 17/71 (23%), Positives = 35/71 (49%), Gaps = 1/71 (1%)
 Frame = +2

Query: 338 KHIQSSKENHGTVSRKNNEGQFSKEVQQSASEK-NGGADSGEVASDKENVNCDVNHEEVR 514
           ++   ++ N+G     +N G  S    +S S + NGG+++    ++  N   + N+    
Sbjct: 109 RNSNGNRSNNGGNRTNSNNGNRSANASRSNSARNNGGSNTNRSNNNNNNNRSNNNNRSNT 168

Query: 515 QHQRTNASGGR 547
            + RTN++G R
Sbjct: 169 SNNRTNSTGNR 179

>EAF7_YARLI (Q6CF40) Chromatin modification-related protein EAF7|
          Length = 354

 Score = 31.2 bits (69), Expect = 2.3
 Identities = 23/90 (25%), Positives = 41/90 (45%), Gaps = 2/90 (2%)
 Frame = +2

Query: 308 LAKRSVVGSGKHIQSSKENHGTVSRKNNEGQFSKEVQQSASEKNGGADSGEVASDKENVN 487
           LA+  +   G+  Q  +EN G       EG    E  + + E+  G +SGE  S+  + +
Sbjct: 203 LAETKIKVEGEQ-QEREENGGEEEHDTMEGSAEPEEAEKSEEEGEGEESGESESESGSES 261

Query: 488 CDVNHEEVRQHQRTNA--SGGRKGRYRSQG 571
              +  +  + +RT A  +   +GR  S+G
Sbjct: 262 QSDSDAQTGRQRRTRAATAAAVRGRGTSKG 291

>DPO5_SCHPO (O60094) DNA polymerase V (EC 2.7.7.7) (POL V)|
          Length = 959

 Score = 31.2 bits (69), Expect = 2.3
 Identities = 13/48 (27%), Positives = 30/48 (62%)
 Frame = +3

Query: 330 DQESISSLRKKIMEQFRERTTRASFQKKYNSRHRKKMVVLIQERLLQI 473
           + E + +L +K+ E FRER   ++ +KK N++  K+ +V  + +++ +
Sbjct: 749 NDEQMLALDEKLAEVFRERKKASNKEKKKNAQETKQQIVQFKVKVIDL 796

>41_MOUSE (P48193) Protein 4.1 (Band 4.1) (P4.1) (4.1R)|
          Length = 858

 Score = 31.2 bits (69), Expect = 2.3
 Identities = 18/71 (25%), Positives = 32/71 (45%)
 Frame = +2

Query: 332 SGKHIQSSKENHGTVSRKNNEGQFSKEVQQSASEKNGGADSGEVASDKENVNCDVNHEEV 511
           + +H Q  +E  G  +    E Q  +  Q +A+E   G+D GE      N +   + +  
Sbjct: 13  NSQHQQQKEEGEGATNSGQQETQLEEASQAAAAE---GSDQGEQKLKASNGDTPTHEDLT 69

Query: 512 RQHQRTNASGG 544
           +  +RT+ S G
Sbjct: 70  KNKERTSESRG 80

>MED2_YEAST (Q12124) RNA polymerase II mediator complex subunit 2|
          Length = 431

 Score = 31.2 bits (69), Expect = 2.3
 Identities = 20/82 (24%), Positives = 36/82 (43%)
 Frame = +2

Query: 329 GSGKHIQSSKENHGTVSRKNNEGQFSKEVQQSASEKNGGADSGEVASDKENVNCDVNHEE 508
           G   + +S+K N+G    KNN      E   ++SEKN   ++    ++ +N N + N+  
Sbjct: 292 GKDNNNESNKNNNGDEKNKNNNED--NENNNNSSEKNNNNNNNNNNNNDDNGNNNNNNSG 349

Query: 509 VRQHQRTNASGGRKGRYRSQGH 574
              +  TN     K    + G+
Sbjct: 350 NDNNNTTNNDSNNKNNSITTGN 371

>IGA1B_STRPN (Q54875) Immunoglobulin A1 protease precursor (EC 3.4.24.13) (IgA1|
           protease) (IgA-specific zinc metalloproteinase)
          Length = 1927

 Score = 30.8 bits (68), Expect = 3.0
 Identities = 17/53 (32%), Positives = 28/53 (52%)
 Frame = +2

Query: 359 ENHGTVSRKNNEGQFSKEVQQSASEKNGGADSGEVASDKENVNCDVNHEEVRQ 517
           E +GT ++  N G  + E  Q+  E + G +S E  S K N +    +EE++Q
Sbjct: 573 EKNGTATKPENSGNTTSENGQTEPEPSNG-NSTEDVSTKSNTSNSNGNEEIKQ 624

>NKX28_MOUSE (O70584) Homeobox protein Nkx-2.8 (Homeobox protein NK-2 homolog H)|
           (Homeobox protein Nkx-2.9)
          Length = 235

 Score = 30.8 bits (68), Expect = 3.0
 Identities = 14/35 (40%), Positives = 20/35 (57%)
 Frame = -1

Query: 113 LIQISPVNSPGRNPGVDFPPQQSFSSRLSTHCMVP 9
           L+   P ++ GR  G    PQ+  S+RL+T C VP
Sbjct: 171 LVHDRPPSNNGRGEGTSAVPQEKCSARLATACPVP 205

>IGA1A_STRPN (Q97QP7) Immunoglobulin A1 protease precursor (EC 3.4.24.13) (IgA1|
           protease) (IgA-specific zinc metalloproteinase)
          Length = 2004

 Score = 30.4 bits (67), Expect = 3.9
 Identities = 15/53 (28%), Positives = 29/53 (54%)
 Frame = +2

Query: 359 ENHGTVSRKNNEGQFSKEVQQSASEKNGGADSGEVASDKENVNCDVNHEEVRQ 517
           E +GT ++  N G  + E  Q+  E + G  + +V+++    N + N EE++Q
Sbjct: 653 EKNGTATKPENSGNTTSENGQTEPEPSNGNSTEDVSTESNTSNSNGN-EEIKQ 704

>RBF1_CAEEL (P41885) Rabphilin-1|
          Length = 1106

 Score = 30.4 bits (67), Expect = 3.9
 Identities = 22/78 (28%), Positives = 37/78 (47%), Gaps = 3/78 (3%)
 Frame = +2

Query: 347 QSSKENH---GTVSRKNNEGQFSKEVQQSASEKNGGADSGEVASDKENVNCDVNHEEVRQ 517
           Q+S ++H   GT  R +N  + +  V QSAS  +       ++S     NC+ +   V +
Sbjct: 614 QASHDHHSGGGTPRRISNPDRTTSRVAQSASGTSLVTPPPPISSRTSPDNCNSSPLNVME 673

Query: 518 HQRTNASGGRKGRYRSQG 571
           H+ ++AS    G  R  G
Sbjct: 674 HKSSSASTASSGGNRRVG 691

>PAG1_HUMAN (Q9NWQ8) Phosphoprotein associated with glycosphingolipid-enriched|
           microdomains 1 (Transmembrane adapter protein PAG)
           (Csk-binding protein) (Transmembrane phosphoprotein Cbp)
          Length = 432

 Score = 30.0 bits (66), Expect = 5.0
 Identities = 16/62 (25%), Positives = 33/62 (53%), Gaps = 6/62 (9%)
 Frame = +2

Query: 347 QSSKENHGTVSRKNNEGQFSKEVQQSA------SEKNGGADSGEVASDKENVNCDVNHEE 508
           Q S ++   ++  +++  FS+ V   A      SE+NG   +G++ S+   + C  ++EE
Sbjct: 48  QHSGDHENLMNVPSDKEMFSRSVTSLATDAPASSEQNGALTNGDILSEDSTLTCMQHYEE 107

Query: 509 VR 514
           V+
Sbjct: 108 VQ 109

>DA2D_PHYBI (P21850) [D-Ala(2)] deltorphins precursor [Contains:|
           [D-Ala(2)]dermorphin-like; [D-Ala(2)]deltorphin II;
           [D-Ala(2)]deltorphin I]
          Length = 227

 Score = 30.0 bits (66), Expect = 5.0
 Identities = 24/88 (27%), Positives = 40/88 (45%), Gaps = 1/88 (1%)
 Frame = +2

Query: 266 NDERNWRTGMRVILLAKRSVVGSGKHIQSSKENHGTVSRKNNEGQFSKEVQQSASEKNGG 445
           N+E N   G  +   A   V G  K ++   E       +N+E     E+++ A +  GG
Sbjct: 93  NEEENHEEGSEMKRYAFEVVGGEAKKMKREPEEENENEEENHEE--GSEMKRYAFDVVGG 150

Query: 446 -ADSGEVASDKENVNCDVNHEEVRQHQR 526
            A   +   ++EN N + NHEE  + +R
Sbjct: 151 EAKKMKREPEEENENEEENHEEGSEMKR 178



 Score = 29.3 bits (64), Expect = 8.6
 Identities = 24/88 (27%), Positives = 40/88 (45%), Gaps = 1/88 (1%)
 Frame = +2

Query: 266 NDERNWRTGMRVILLAKRSVVGSGKHIQSSKENHGTVSRKNNEGQFSKEVQQSASEKNGG 445
           N+E N   G  +   A   V G  K ++   E       +N+E     E+++ A +  GG
Sbjct: 129 NEEENHEEGSEMKRYAFDVVGGEAKKMKREPEEENENEEENHEE--GSEMKRYAFDVVGG 186

Query: 446 -ADSGEVASDKENVNCDVNHEEVRQHQR 526
            A   +   ++EN N + NHEE  + +R
Sbjct: 187 EAKKMKREPEEENENEEENHEEGSEMKR 214

>MYEF2_MOUSE (Q8C854) Myelin expression factor 2 (MyEF-2) (MEF-2)|
          Length = 591

 Score = 29.6 bits (65), Expect = 6.6
 Identities = 12/30 (40%), Positives = 17/30 (56%)
 Frame = +2

Query: 38  KKRTVVVENLPLDFSLESLQEKFGSVGKIM 127
           K   + V NLP D + + L+EKF   G +M
Sbjct: 512 KGNQIFVRNLPFDLTWQKLKEKFSQCGHVM 541

>MYEF2_HUMAN (Q9P2K5) Myelin expression factor 2 (MyEF-2) (MST156)|
          Length = 600

 Score = 29.6 bits (65), Expect = 6.6
 Identities = 12/30 (40%), Positives = 17/30 (56%)
 Frame = +2

Query: 38  KKRTVVVENLPLDFSLESLQEKFGSVGKIM 127
           K   + V NLP D + + L+EKF   G +M
Sbjct: 521 KGNQIFVRNLPFDLTWQKLKEKFSQCGHVM 550

>LA_RAT (P38656) Lupus La protein homolog (La ribonucleoprotein) (La|
           autoantigen homolog)
          Length = 415

 Score = 29.6 bits (65), Expect = 6.6
 Identities = 14/42 (33%), Positives = 23/42 (54%)
 Frame = +2

Query: 8   EVPCNELKDVKKRTVVVENLPLDFSLESLQEKFGSVGKIMKI 133
           EV      DVK R+V ++  P D +L+ ++E     G+I+ I
Sbjct: 99  EVTDEYKNDVKNRSVYIKGFPTDATLDDIKEWLDDKGQILNI 140

>LA_MOUSE (P32067) Lupus La protein homolog (La ribonucleoprotein) (La|
           autoantigen homolog)
          Length = 415

 Score = 29.6 bits (65), Expect = 6.6
 Identities = 14/42 (33%), Positives = 23/42 (54%)
 Frame = +2

Query: 8   EVPCNELKDVKKRTVVVENLPLDFSLESLQEKFGSVGKIMKI 133
           EV      DVK R+V ++  P D +L+ ++E     G+I+ I
Sbjct: 99  EVTDEYKNDVKNRSVYIKGFPTDATLDDIKEWLDDKGQILNI 140

>HORN_HUMAN (Q86YZ3) Hornerin|
          Length = 2850

 Score = 29.6 bits (65), Expect = 6.6
 Identities = 22/88 (25%), Positives = 38/88 (43%), Gaps = 5/88 (5%)
 Frame = +2

Query: 329  GSGKHIQSSKENHGTVSRKNNEGQFSKEVQQSASEKNGGADSGEVASDKENVNCDVNHEE 508
            GSG    SS   HG+ S +++         QS+     G+ SG  +S +++ +       
Sbjct: 910  GSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSR 969

Query: 509  VRQHQRTNASGGRKGRY-----RSQGHG 577
              QH  ++ S    G++     +S GHG
Sbjct: 970  SEQHGSSSGSSSSYGQHGSGSRQSLGHG 997

>ATG18_KLULA (Q6CS21) Autophagy-related protein 18|
          Length = 500

 Score = 29.3 bits (64), Expect = 8.6
 Identities = 16/61 (26%), Positives = 26/61 (42%)
 Frame = +2

Query: 320 SVVGSGKHIQSSKENHGTVSRKNNEGQFSKEVQQSASEKNGGADSGEVASDKENVNCDVN 499
           +V  S K +   K    TV  K+NE     E++     + G  D  +   D+E  + + N
Sbjct: 301 AVCSSSKTVHIFKLGKNTVDNKSNELNSDDEIEDDLVPRYGDEDEEDEEIDEEATSINSN 360

Query: 500 H 502
           H
Sbjct: 361 H 361

>TOP1_DROME (P30189) DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)|
          Length = 972

 Score = 29.3 bits (64), Expect = 8.6
 Identities = 23/89 (25%), Positives = 36/89 (40%), Gaps = 8/89 (8%)
 Frame = +2

Query: 332 SGKHIQSSKENHGTVSRK---NNEGQFSKEVQQSASE----KNGGADSGEVASDKENVNC 490
           S KH  SSK+ H    R+   +N    SKE + S+ +    K+  + S     DKE    
Sbjct: 45  SSKHKSSSKDKHRDREREHKSSNSSSSSKEHKSSSRDKDRHKSSSSSSKHRDKDKERDGS 104

Query: 491 DVNHEEVRQHQRTNASGGRKGRYR-SQGH 574
             +H         +  G    +++ S GH
Sbjct: 105 SNSHRSGSSSSHKDKDGSSSSKHKSSSGH 133

>TUP12_SCHPO (Q9UUG8) Transcriptional repressor tup12|
          Length = 586

 Score = 29.3 bits (64), Expect = 8.6
 Identities = 18/61 (29%), Positives = 27/61 (44%), Gaps = 4/61 (6%)
 Frame = +2

Query: 287 TGMRVILLAKRSVVGSGKHIQSSKENHG----TVSRKNNEGQFSKEVQQSASEKNGGADS 454
           T ++  L A+R  + SG   QSSK  HG    +  +  N G F+ +        N G+  
Sbjct: 93  TSLKAQLEARRKEIASGVVPQSSKTKHGRNSVSFGKYGNAGPFNSDNSSKPLILNNGSSG 152

Query: 455 G 457
           G
Sbjct: 153 G 153


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 85,739,178
Number of Sequences: 219361
Number of extensions: 1756071
Number of successful extensions: 5323
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 5077
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5315
length of database: 80,573,946
effective HSP length: 106
effective length of database: 57,321,680
effective search space used: 4986986160
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)