ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bags37g17 |
|---|---|
| Clone Library Name | barley_pub |
>M2OM_HUMAN (Q02978) Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP)| (Solute carrier family 25 member 11) Length = 313 Score = 175 bits (444), Expect = 9e-44 Identities = 101/187 (54%), Positives = 127/187 (67%), Gaps = 8/187 (4%) Frame = +3 Query: 114 KTIKPFVNGGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAKTMY-------ANEGLGS 269 K++K F+ GG +GM AT +QP+D++K ++QL GEG+ + KT + EGL Sbjct: 20 KSVK-FLFGGLAGMGATVFVQPLDLVKNRMQLSGEGAKTREYKTSFHALTSILKAEGLRG 78 Query: 270 FYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGS 449 Y GLSAGLLRQATYTT RLG + VL + A DG P + KA IG+TAGA GA VG+ Sbjct: 79 IYTGLSAGLLRQATYTTTRLGIYTVLFERLTGA-DGTPPGFLLKAVIGMTAGATGAFVGT 137 Query: 450 PADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGM 629 PA++ALIRM AD LPA QRR YKN F+AL RIT +EGVL LW+G PT+ RA+ +N Sbjct: 138 PAEVALIRMTADGRLPADQRRGYKNVFNALIRITREEGVLTLWRGCIPTMARAVVVNAAQ 197 Query: 630 LASYDQS 650 LASY QS Sbjct: 198 LASYSQS 204 Score = 37.4 bits (85), Expect = 0.040 Identities = 28/118 (23%), Positives = 49/118 (41%), Gaps = 1/118 (0%) Frame = +3 Query: 255 EGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIG-LTAGAI 431 EG+ + ++G + R A+L S+ +K + G + F + +G + Sbjct: 174 EGVLTLWRGCIPTMARAVVVNAAQLASYS--QSKQFLLDSGYFSDNILCHFCASMISGLV 231 Query: 432 GACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVR 605 P D+A R+Q + + YKN L+++ EG +LWKG P R Sbjct: 232 TTAASMPVDIAKTRIQNMRMIDG--KPEYKNGLDVLFKVVRYEGFFSLWKGFTPYYAR 287
>M2OM_MOUSE (Q9CR62) Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP)| (Solute carrier family 25 member 11) Length = 313 Score = 172 bits (435), Expect = 1e-42 Identities = 99/187 (52%), Positives = 125/187 (66%), Gaps = 8/187 (4%) Frame = +3 Query: 114 KTIKPFVNGGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAKTMY-------ANEGLGS 269 K++K F+ GG +GM AT +QP+D++K ++QL GEG+ + KT + EGL Sbjct: 20 KSVK-FLFGGLAGMGATVFVQPLDLVKNRMQLSGEGAKTREYKTSFHALTSILKTEGLKG 78 Query: 270 FYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGS 449 Y GLSAGLLRQATYTT RLG + VL + A DG P + KA IG+TAGA GA VG+ Sbjct: 79 IYTGLSAGLLRQATYTTTRLGIYTVLFERLTGA-DGTPPGFLLKALIGMTAGATGAFVGT 137 Query: 450 PADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGM 629 PA++ALIRM AD LPA QRR YKN F+AL RI +EGV LW+G PT+ RA+ +N Sbjct: 138 PAEVALIRMTADGRLPADQRRGYKNVFNALVRIAREEGVPTLWRGCIPTMARAVVVNAAQ 197 Query: 630 LASYDQS 650 LASY QS Sbjct: 198 LASYSQS 204 Score = 35.0 bits (79), Expect = 0.20 Identities = 27/118 (22%), Positives = 47/118 (39%), Gaps = 1/118 (0%) Frame = +3 Query: 255 EGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIG-LTAGAI 431 EG+ + ++G + R A+L S+ +K + G + F + +G + Sbjct: 174 EGVPTLWRGCIPTMARAVVVNAAQLASYS--QSKQFLLDSGYFSDNILCHFCASMISGLV 231 Query: 432 GACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVR 605 P D+ R+Q + + YKN L ++ EG +LWKG P R Sbjct: 232 TTAASMPVDIVKTRIQNMRMIDG--KPEYKNGLDVLLKVVRYEGFFSLWKGFTPYYAR 287
>M2OM_BOVIN (P22292) Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP)| (Solute carrier family 25 member 11) Length = 313 Score = 171 bits (432), Expect = 2e-42 Identities = 98/187 (52%), Positives = 125/187 (66%), Gaps = 8/187 (4%) Frame = +3 Query: 114 KTIKPFVNGGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAKTMY-------ANEGLGS 269 K++K F+ GG +GM AT +QP+D++K ++QL GEG+ + KT + EGL Sbjct: 20 KSVK-FLFGGLAGMGATVFVQPLDLVKNRMQLSGEGAKTREYKTSFHALISILRAEGLRG 78 Query: 270 FYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGS 449 Y GLSAGLLRQATYTT RLG + VL + A DG P + KA IG+TAGA GA VG+ Sbjct: 79 IYTGLSAGLLRQATYTTTRLGIYTVLFERLTGA-DGTPPGFLLKAVIGMTAGATGAFVGT 137 Query: 450 PADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGM 629 PA++ALIRM AD LP QRR YKN F+AL+RI +EGV LW+G PT+ RA+ +N Sbjct: 138 PAEVALIRMTADGRLPVDQRRGYKNVFNALFRIVQEEGVPTLWRGCIPTMARAVVVNAAQ 197 Query: 630 LASYDQS 650 LASY QS Sbjct: 198 LASYSQS 204 Score = 35.0 bits (79), Expect = 0.20 Identities = 27/118 (22%), Positives = 47/118 (39%), Gaps = 1/118 (0%) Frame = +3 Query: 255 EGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIG-LTAGAI 431 EG+ + ++G + R A+L S+ +K + G + F + +G + Sbjct: 174 EGVPTLWRGCIPTMARAVVVNAAQLASYS--QSKQFLLDSGYFSDNILCHFCASMISGLV 231 Query: 432 GACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVR 605 P D+ R+Q + + YKN L ++ EG +LWKG P R Sbjct: 232 TTAASMPVDIVKTRIQNMRMIDG--KPEYKNGLDVLVKVVRYEGFFSLWKGFTPYYAR 287
>M2OM_RAT (P97700) Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP)| (Solute carrier family 25 member 11) Length = 313 Score = 168 bits (425), Expect = 2e-41 Identities = 98/187 (52%), Positives = 123/187 (65%), Gaps = 8/187 (4%) Frame = +3 Query: 114 KTIKPFVNGGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAKTMY-------ANEGLGS 269 K++K F+ GG +GM AT +QP+D++ ++QL GEG+ + KT + EGL Sbjct: 20 KSVK-FLFGGLAGMGATVFVQPLDLVXNRMQLSGEGAKTREYKTSFHALTSILKAEGLRG 78 Query: 270 FYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGS 449 Y GLSAGLLRQATYTT RLG + VL + A DG P + KA IG+TAGA GA VG Sbjct: 79 IYTGLSAGLLRQATYTTTRLGIYTVLFERLTGA-DGTPPGFLLKALIGMTAGATGAFVGP 137 Query: 450 PADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGM 629 PA++ALIRM AD LPA QRR YKN F+AL RI +EGV LW+G PT+ RA+ +N Sbjct: 138 PAEVALIRMTADGRLPADQRRGYKNVFNALIRIAREEGVPTLWRGCIPTMARAVVVNAAQ 197 Query: 630 LASYDQS 650 LASY QS Sbjct: 198 LASYSQS 204 Score = 36.2 bits (82), Expect = 0.089 Identities = 26/117 (22%), Positives = 47/117 (40%) Frame = +3 Query: 255 EGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIG 434 EG+ + ++G + R A+L S+ +++ L I + +G + Sbjct: 174 EGVPTLWRGCIPTMARAVVVNAAQLASYSQSKQFLLDSGYFSDNILCHFCAI-MISGLVT 232 Query: 435 ACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVR 605 P D+ R+Q + ++ YKN L ++ EG +LWKG P R Sbjct: 233 TAASMPVDIVKTRIQNMRMID--EKPEYKNGLDVLLKVVRYEGFFSLWKGFTPYYAR 287
>DIC_HUMAN (Q9UBX3) Mitochondrial dicarboxylate carrier (Solute carrier family| 25 member 10) Length = 287 Score = 117 bits (292), Expect = 4e-26 Identities = 65/181 (35%), Positives = 99/181 (54%), Gaps = 7/181 (3%) Frame = +3 Query: 138 GGASGMLATCVIQPIDMIKVKIQLGE-------GSAAQVAKTMYANEGLGSFYKGLSAGL 296 GG + A C P+D++KV +Q + G A +V +T +G+ + Y GLSA L Sbjct: 13 GGLASCGAACCTHPLDLLKVHLQTQQEVKLRMTGMALRVVRT----DGILALYSGLSASL 68 Query: 297 LRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRM 476 RQ TY+ R + + ++ + + G PLP +K +G +G G VG+PADL +RM Sbjct: 69 CRQMTYSLTRFAIYETVRDRVAKGSQG-PLPFHEKVLLGSVSGLAGGFVGTPADLVNVRM 127 Query: 477 QADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYDQSVE 656 Q D LP QRR+Y +A LYR+ +EG+ L+ GA R + +G L+ YDQ+ + Sbjct: 128 QNDVKLPQGQRRNYAHALDGLYRVAREEGLRRLFSGATMASSRGALVTVGQLSCYDQAKQ 187 Query: 657 L 659 L Sbjct: 188 L 188
>DIC1_YEAST (Q06143) Mitochondrial dicarboxylate transporter (Dicarboxylate| carrier 1) (DTP) Length = 298 Score = 115 bits (289), Expect = 9e-26 Identities = 72/185 (38%), Positives = 108/185 (58%), Gaps = 8/185 (4%) Frame = +3 Query: 114 KTIK-PFVNGGASGMLATCVIQPIDMIKVKIQ---LGEGSAAQVAKTMYANEGLGSFYKG 281 K IK P+ GGA+G+ AT V P+D+ KV++Q + + + ++ +++ ANEG+ Y G Sbjct: 11 KNIKYPWWYGGAAGIFATMVTHPLDLAKVRLQAAPMPKPTLFRMLESILANEGVVGLYSG 70 Query: 282 LSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFI---GLTAGAIGACVGSP 452 LSA +LRQ TYTT R G++ +L I L A++ + +GAIG G+ Sbjct: 71 LSAAVLRQCTYTTVRFGAYDLLKENVIPREQ-----LTNMAYLLPCSMFSGAIGGLAGNF 125 Query: 453 ADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVL-ALWKGAGPTVVRAMSLNMGM 629 AD+ IRMQ DS L AA+RR+YKNA +Y+I EG L L+ G P +VR + + Sbjct: 126 ADVVNIRMQNDSALEAAKRRNYKNAIDGVYKIYRYEGGLKTLFTGWKPNMVRGILMTASQ 185 Query: 630 LASYD 644 + +YD Sbjct: 186 VVTYD 190 Score = 29.6 bits (65), Expect = 8.3 Identities = 22/76 (28%), Positives = 33/76 (43%), Gaps = 3/76 (3%) Frame = +3 Query: 147 SGMLATCVIQPIDMIKVKIQLGEGS---AAQVAKTMYANEGLGSFYKGLSAGLLRQATYT 317 +G++AT V P D++K +I G G A ++ EG ++G Sbjct: 217 AGLVATTVCSPADVMKTRIMNGSGDHQPALKILADAVRKEGPSFMFRGWLPSF------- 269 Query: 318 TARLGSFRVLTNKAIE 365 RLG F +L AIE Sbjct: 270 -TRLGPFTMLIFFAIE 284
>DIC_MOUSE (Q9QZD8) Mitochondrial dicarboxylate carrier (Solute carrier family| 25 member 10) Length = 287 Score = 113 bits (282), Expect = 6e-25 Identities = 65/181 (35%), Positives = 96/181 (53%), Gaps = 7/181 (3%) Frame = +3 Query: 138 GGASGMLATCVIQPIDMIKVKIQLGE-------GSAAQVAKTMYANEGLGSFYKGLSAGL 296 GG + A C P+D++KV +Q + G A QV +T +G + Y GLSA L Sbjct: 12 GGLASCGAACCTHPLDLLKVHLQTQQEVKLRMTGMALQVVRT----DGFLALYNGLSASL 67 Query: 297 LRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRM 476 RQ TY+ R + + + + + G PLP K +G +G G VG+PADL +RM Sbjct: 68 CRQMTYSLTRFAIYETMRDYMTKDSQG-PLPFYNKVLLGGISGLTGGFVGTPADLVNVRM 126 Query: 477 QADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYDQSVE 656 Q D LP +QRR+Y +A LYR+ +E + L+ GA R + +G L+ YDQ+ + Sbjct: 127 QNDMKLPPSQRRNYSHALDGLYRVAREESLRKLFSGATMASSRGALVTVGQLSCYDQAKQ 186 Query: 657 L 659 L Sbjct: 187 L 187
>DIC1_CANGA (Q6FTN2) Mitochondrial dicarboxylate transporter (Dicarboxylate| carrier 1) Length = 295 Score = 107 bits (267), Expect = 3e-23 Identities = 65/177 (36%), Positives = 99/177 (55%), Gaps = 4/177 (2%) Frame = +3 Query: 126 PFVNGGASGMLATCVIQPIDMIKVKIQ---LGEGSAAQVAKTMYANEGLGSFYKGLSAGL 296 P+ GGA+G+ A P+D+ KV++Q + + + Q+ +++ NEG+ Y GLSA L Sbjct: 9 PWWYGGAAGIFAVMNTHPLDLTKVRLQAAPIPKPTIVQMLRSILKNEGIVGLYAGLSASL 68 Query: 297 LRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRM 476 LRQ TYTTAR G + L I + + + A + +GA+G G+ ADL IRM Sbjct: 69 LRQCTYTTARFGMYDALKEHVIPRDKLTNMWYLLGA--SMVSGALGGLAGNFADLINIRM 126 Query: 477 QADSTLPAAQRRHYKNAFHALYRITADEGVLALW-KGAGPTVVRAMSLNMGMLASYD 644 Q DS LP +RR+YKNA + +I EG +L+ G P +VR + + + +YD Sbjct: 127 QNDSALPLDKRRNYKNAIDGMVKIYKAEGAKSLFLTGWKPNMVRGVLMTASQVVTYD 183
>UCP1_RAT (P04633) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 306 Score = 89.0 bits (219), Expect = 1e-17 Identities = 55/180 (30%), Positives = 87/180 (48%), Gaps = 10/180 (5%) Frame = +3 Query: 135 NGGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAK---------TMYANEGLGSFYKGL 284 + G S LA + P+D KV++Q+ GEG A+ + T+ EGL Y GL Sbjct: 18 SAGVSACLADIITFPLDTAKVRLQIQGEGQASSTIRYKGVLGTITTLAKTEGLPKLYSGL 77 Query: 285 SAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLA 464 AG+ RQ ++ + R+G + + + + P L K GL G + +G P ++ Sbjct: 78 PAGIQRQISFASLRIGLYDTV-QEYFSSGRETPASLGSKISAGLMTGGVAVFIGQPTEVV 136 Query: 465 LIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYD 644 +RMQA S L + R Y ++A I E + LWKG P ++R + +N L +YD Sbjct: 137 KVRMQAQSHLHGIKPR-YTGTYNAYRVIATTESLSTLWKGTTPNLMRNVIINCTELVTYD 195 Score = 35.0 bits (79), Expect = 0.20 Identities = 21/78 (26%), Positives = 36/78 (46%), Gaps = 4/78 (5%) Frame = +3 Query: 147 SGMLATCVIQPIDMIKVK-IQLGEG---SAAQVAKTMYANEGLGSFYKGLSAGLLRQATY 314 +G T + P+D++K + I G S A TMY EG +F+KG + LR ++ Sbjct: 221 AGFCTTLLASPVDVVKTRFINSLPGQYPSVPSCAMTMYTKEGPAAFFKGFAPSFLRLGSW 280 Query: 315 TTARLGSFRVLTNKAIEA 368 F L + +++ Sbjct: 281 NVIMFVCFEQLKKELMKS 298
>UCP1_MOUSE (P12242) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 306 Score = 88.2 bits (217), Expect = 2e-17 Identities = 55/180 (30%), Positives = 87/180 (48%), Gaps = 10/180 (5%) Frame = +3 Query: 135 NGGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAK---------TMYANEGLGSFYKGL 284 + G S LA + P+D KV++Q+ GEG A+ + T+ EGL Y GL Sbjct: 18 SAGVSACLADIITFPLDTAKVRLQIQGEGQASSTIRYKGVLGTITTLAKTEGLPKLYSGL 77 Query: 285 SAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLA 464 AG+ RQ ++ + R+G + + + + P L K GL G + +G P ++ Sbjct: 78 PAGIQRQISFASLRIGLYDSV-QEYFSSGRETPASLGNKISAGLMTGGVAVFIGQPTEVV 136 Query: 465 LIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYD 644 +RMQA S L + R Y ++A I E + LWKG P ++R + +N L +YD Sbjct: 137 KVRMQAQSHLHGIKPR-YTGTYNAYRVIATTESLSTLWKGTTPNLMRNVIINCTELVTYD 195 Score = 33.5 bits (75), Expect = 0.58 Identities = 21/78 (26%), Positives = 36/78 (46%), Gaps = 4/78 (5%) Frame = +3 Query: 147 SGMLATCVIQPIDMIKVK-IQLGEG---SAAQVAKTMYANEGLGSFYKGLSAGLLRQATY 314 +G T + P+D++K + I G S A +MY EG +F+KG A LR ++ Sbjct: 221 AGFCTTLLASPVDVVKTRFINSLPGQYPSVPSCAMSMYTKEGPTAFFKGFVASFLRLGSW 280 Query: 315 TTARLGSFRVLTNKAIEA 368 F L + +++ Sbjct: 281 NVIMFVCFEQLKKELMKS 298 Score = 29.6 bits (65), Expect = 8.3 Identities = 19/87 (21%), Positives = 34/87 (39%), Gaps = 4/87 (4%) Frame = +3 Query: 408 IGLTAGAIGACVGS----PADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLAL 575 + + + + AC+ P D A +R+Q A+ YK + + EG+ L Sbjct: 14 VKIFSAGVSACLADIITFPLDTAKVRLQIQGEGQASSTIRYKGVLGTITTLAKTEGLPKL 73 Query: 576 WKGAGPTVVRAMSLNMGMLASYDQSVE 656 + G + R +S + YD E Sbjct: 74 YSGLPAGIQRQISFASLRIGLYDSVQE 100
>UCP1_PHOSU (Q9ER18) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 307 Score = 86.3 bits (212), Expect = 8e-17 Identities = 52/180 (28%), Positives = 87/180 (48%), Gaps = 10/180 (5%) Frame = +3 Query: 135 NGGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAK---------TMYANEGLGSFYKGL 284 + G + LA + P+D KV++Q+ GEG + + T+ EGL Y GL Sbjct: 19 SAGVAACLADIITFPLDTAKVRLQIQGEGQTSSTIRYKGVLGTITTLAKTEGLPKLYSGL 78 Query: 285 SAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLA 464 AG+ RQ ++ + R+G + + + + P LV + GL G + +G P ++ Sbjct: 79 PAGIQRQISFASLRIGLYDTV-QEYFSSGKETPPTLVNRISAGLMTGGVAVFIGQPTEVV 137 Query: 465 LIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYD 644 +R+QA S L + R Y ++A I E + LWKG P ++R + +N L +YD Sbjct: 138 KVRLQAQSHLHGIKPR-YTGTYNAYRIIATTESLSTLWKGTTPNLLRNVIINCTELVTYD 196 Score = 31.2 bits (69), Expect = 2.9 Identities = 21/78 (26%), Positives = 35/78 (44%), Gaps = 4/78 (5%) Frame = +3 Query: 147 SGMLATCVIQPIDMIKVK-IQLGEG---SAAQVAKTMYANEGLGSFYKGLSAGLLRQATY 314 +G T + P D++K + I G S A TM+ EG +F+KG LR A++ Sbjct: 222 AGFCTTFLASPADVVKTRFINSLPGQYPSVPSCAMTMFTKEGPTAFFKGFVPSFLRLASW 281 Query: 315 TTARLGSFRVLTNKAIEA 368 F L + +++ Sbjct: 282 NVIMFVCFEQLKKELMKS 299
>UCP3_CANFA (Q9N2I9) Mitochondrial uncoupling protein 3 (UCP 3)| Length = 311 Score = 85.9 bits (211), Expect = 1e-16 Identities = 58/193 (30%), Positives = 84/193 (43%), Gaps = 17/193 (8%) Frame = +3 Query: 117 TIKPFVNGGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAK------------TMYANE 257 T F+ G + A + P+D KV++Q+ GE A Q A+ TM E Sbjct: 13 TAVKFLGAGTAACFADLLTFPLDTAKVRLQIQGENQATQAARRIQYRGVLGTILTMVRTE 72 Query: 258 GLGSFYKGLSAGLLRQATYTTARLGSF----RVLTNKAIEANDGRPLPLVQKAFIGLTAG 425 G S Y GL AGL RQ ++ + R+G + + T K + + + + G T G Sbjct: 73 GPRSPYNGLVAGLQRQMSFASIRIGLYDSVKQFYTPKGSDHSS-----ITTRILAGCTTG 127 Query: 426 AIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVR 605 A+ P D+ +R QA L A R Y A I +EGV LWKG P + R Sbjct: 128 AMAVSCAQPTDVVKVRFQASIHLGAGSNRKYSGTMDAYRTIAREEGVRGLWKGTLPNITR 187 Query: 606 AMSLNMGMLASYD 644 +N + +YD Sbjct: 188 NAIVNCAEMVTYD 200 Score = 57.8 bits (138), Expect = 3e-08 Identities = 48/183 (26%), Positives = 79/183 (43%), Gaps = 13/183 (7%) Frame = +3 Query: 138 GGASGMLATCVIQPIDMIKVKIQ----LGEGSAAQVAKTMYA------NEGLGSFYKGLS 287 G +G +A QP D++KV+ Q LG GS + + TM A EG+ +KG Sbjct: 123 GCTTGAMAVSCAQPTDVVKVRFQASIHLGAGSNRKYSGTMDAYRTIAREEGVRGLWKGTL 182 Query: 288 AGLLRQATYTTARLGSFRVLTNKAIEAN---DGRPLPLVQKAFIGLTAGAIGACVGSPAD 458 + R A A + ++ ++ K ++ + D P L+ AG V SP D Sbjct: 183 PNITRNAIVNCAEMVTYDIIKEKLLDYHLLTDNFPCHLIS----AFGAGFCATVVASPVD 238 Query: 459 LALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLAS 638 + R P Q Y + + ++ EG A +KG P+ +R + N+ M + Sbjct: 239 VVKTRYMNS---PPGQ---YCSPLDCMLKMVTQEGPTAFYKGFTPSFLRLGTWNVVMFVT 292 Query: 639 YDQ 647 Y+Q Sbjct: 293 YEQ 295
>UCP3_HUMAN (P55916) Mitochondrial uncoupling protein 3 (UCP 3)| Length = 312 Score = 85.9 bits (211), Expect = 1e-16 Identities = 60/190 (31%), Positives = 86/190 (45%), Gaps = 18/190 (9%) Frame = +3 Query: 129 FVNGGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAK------------TMYANEGLGS 269 F+ G + A V P+D KV++Q+ GE A Q A+ TM EG S Sbjct: 17 FLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEGPCS 76 Query: 270 FYKGLSAGLLRQATYTTARLGSF----RVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGA 437 Y GL AGL RQ ++ + R+G + +V T K + + L + G T GA+ Sbjct: 77 PYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSS-----LTTRILAGCTTGAMAV 131 Query: 438 CVGSPADLALIRMQADSTL-PAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMS 614 P D+ +R QA L P+ R Y A I +EGV LWKG P ++R Sbjct: 132 TCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMRNAI 191 Query: 615 LNMGMLASYD 644 +N + +YD Sbjct: 192 VNCAEVVTYD 201 Score = 54.7 bits (130), Expect = 2e-07 Identities = 47/184 (25%), Positives = 78/184 (42%), Gaps = 14/184 (7%) Frame = +3 Query: 138 GGASGMLATCVIQPIDMIKVKIQ----LGEGSAAQ-------VAKTMYANEGLGSFYKGL 284 G +G +A QP D++KV+ Q LG + + +T+ EG+ +KG Sbjct: 123 GCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGT 182 Query: 285 SAGLLRQATYTTARLGSFRVLTNKAIEAN---DGRPLPLVQKAFIGLTAGAIGACVGSPA 455 ++R A A + ++ +L K ++ + D P V AG V SP Sbjct: 183 LPNIMRNAIVNCAEVVTYDILKEKLLDYHLLTDNFPCHFVS----AFGAGFCATVVASPV 238 Query: 456 DLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLA 635 D+ R P Q Y + + ++ A EG A +KG P+ +R S N+ M Sbjct: 239 DVVKTRYMNS---PPGQ---YFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFV 292 Query: 636 SYDQ 647 +Y+Q Sbjct: 293 TYEQ 296
>UCP2_PIG (O97562) Mitochondrial uncoupling protein 2 (UCP 2)| Length = 309 Score = 85.9 bits (211), Expect = 1e-16 Identities = 59/190 (31%), Positives = 87/190 (45%), Gaps = 14/190 (7%) Frame = +3 Query: 117 TIKPFVNGGASGMLATCVIQPIDMIKVKIQL-----GEGSAAQVAK---------TMYAN 254 T+K F+ G + +A + P+D KV++Q+ G AA A+ TM N Sbjct: 14 TVK-FLGAGTAACIADLITFPLDTAKVRLQIQGERRGPVQAAASAQYRGVLGTILTMVRN 72 Query: 255 EGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIG 434 EG S Y GL AGL RQ ++ + R+G + + K + + G T GA+ Sbjct: 73 EGPRSLYNGLVAGLQRQMSFASVRIGLYDSV--KHFYTKGSEHAGIGSRLLAGSTTGALA 130 Query: 435 ACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMS 614 V P D+ +R QA + A R Y++ A I +EG+ LWKG P V R Sbjct: 131 VAVAQPTDVVKVRFQAQAR--AGGGRRYRSTVDAYKTIAREEGLRGLWKGTSPNVARNAI 188 Query: 615 LNMGMLASYD 644 +N L +YD Sbjct: 189 VNCAELVTYD 198 Score = 61.6 bits (148), Expect = 2e-09 Identities = 51/181 (28%), Positives = 78/181 (43%), Gaps = 11/181 (6%) Frame = +3 Query: 138 GGASGMLATCVIQPIDMIKVKIQL----GEG----SAAQVAKTMYANEGLGSFYKGLSAG 293 G +G LA V QP D++KV+ Q G G S KT+ EGL +KG S Sbjct: 123 GSTTGALAVAVAQPTDVVKVRFQAQARAGGGRRYRSTVDAYKTIAREEGLRGLWKGTSPN 182 Query: 294 LLRQATYTTARLGSFRVLTNKAIEAN---DGRPLPLVQKAFIGLTAGAIGACVGSPADLA 464 + R A A L ++ ++ + ++A+ D P AG + SP D+ Sbjct: 183 VARNAIVNCAELVTYDLIKDTLLKADLMTDDLPCHFTS----AFGAGFCTTVIASPVDVV 238 Query: 465 LIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYD 644 R ++ P Y +A H + EG A +KG P+ +R S N+ M +Y+ Sbjct: 239 KTRYM--NSAPG----QYSSAGHCALTMLQKEGPRAFYKGFTPSFLRLGSWNVVMFVTYE 292 Query: 645 Q 647 Q Sbjct: 293 Q 293
>UCP3_BOVIN (O77792) Mitochondrial uncoupling protein 3 (UCP 3)| Length = 311 Score = 84.3 bits (207), Expect = 3e-16 Identities = 57/189 (30%), Positives = 83/189 (43%), Gaps = 17/189 (8%) Frame = +3 Query: 129 FVNGGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAK------------TMYANEGLGS 269 F+ G + A + P+D KV++Q+ GE AA A+ TM EG S Sbjct: 17 FLAAGTAACFADLLTFPLDTAKVRLQIQGENQAALAARSAQYRGVLGTILTMVRTEGPRS 76 Query: 270 FYKGLSAGLLRQATYTTARLGSF----RVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGA 437 Y GL AGL RQ ++ + R+G + + T K + + ++ + G T GA+ Sbjct: 77 LYSGLVAGLQRQMSFASIRIGLYDSVKQFYTPKGSDHSS-----IITRILAGCTTGAMAV 131 Query: 438 CVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSL 617 P D+ IR QA R Y A I +EGV LWKG P + R + Sbjct: 132 TCAQPTDVVKIRFQASMHTGLGGNRKYSGTMDAYRTIAREEGVRGLWKGILPNITRNAIV 191 Query: 618 NMGMLASYD 644 N G + +YD Sbjct: 192 NCGEMVTYD 200 Score = 55.8 bits (133), Expect = 1e-07 Identities = 46/183 (25%), Positives = 77/183 (42%), Gaps = 13/183 (7%) Frame = +3 Query: 138 GGASGMLATCVIQPIDMIKVKIQL----GEGSAAQVAKTMYA------NEGLGSFYKGLS 287 G +G +A QP D++K++ Q G G + + TM A EG+ +KG+ Sbjct: 123 GCTTGAMAVTCAQPTDVVKIRFQASMHTGLGGNRKYSGTMDAYRTIAREEGVRGLWKGIL 182 Query: 288 AGLLRQATYTTARLGSFRVLTNKAIEAN---DGRPLPLVQKAFIGLTAGAIGACVGSPAD 458 + R A + ++ ++ K ++ + D P V AG V SP D Sbjct: 183 PNITRNAIVNCGEMVTYDIIKEKLLDYHLLTDNFPCHFVS----AFGAGFCATLVASPVD 238 Query: 459 LALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLAS 638 + R P Q Y + F + ++ EG A +KG P+ +R S N+ M + Sbjct: 239 VVKTRYMNS---PPGQ---YHSPFDCMLKMVTQEGPTAFYKGFTPSFLRLGSWNVVMFVT 292 Query: 639 YDQ 647 Y+Q Sbjct: 293 YEQ 295
>UCP2_RAT (P56500) Mitochondrial uncoupling protein 2 (UCP 2)| Length = 309 Score = 84.0 bits (206), Expect = 4e-16 Identities = 57/190 (30%), Positives = 85/190 (44%), Gaps = 14/190 (7%) Frame = +3 Query: 117 TIKPFVNGGASGMLATCVIQPIDMIKVKIQL---GEGSAAQVAK-----------TMYAN 254 T+K F+ G + +A + P+D KV++Q+ +G A A TM Sbjct: 14 TVK-FLGAGTAACIADLITFPLDTAKVRLQIQGESQGLARTAASAQYRGVLGTILTMVRT 72 Query: 255 EGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIG 434 EG S Y GL AGL RQ ++ + R+G + + K + + G T GA+ Sbjct: 73 EGPRSLYNGLVAGLQRQMSFASVRIGLYDSV--KQFYTKGSEHAGIGSRLLAGSTTGALA 130 Query: 435 ACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMS 614 V P D+ +R QA + A R Y++ A I +EG+ LWKG P V R Sbjct: 131 VAVAQPTDVVKVRFQAQAR--AGGGRRYQSTVEAYKTIAREEGIRGLWKGTSPNVARNAI 188 Query: 615 LNMGMLASYD 644 +N L +YD Sbjct: 189 VNCTELVTYD 198 Score = 60.8 bits (146), Expect = 3e-09 Identities = 49/181 (27%), Positives = 76/181 (41%), Gaps = 11/181 (6%) Frame = +3 Query: 138 GGASGMLATCVIQPIDMIKVKIQL----GEG----SAAQVAKTMYANEGLGSFYKGLSAG 293 G +G LA V QP D++KV+ Q G G S + KT+ EG+ +KG S Sbjct: 123 GSTTGALAVAVAQPTDVVKVRFQAQARAGGGRRYQSTVEAYKTIAREEGIRGLWKGTSPN 182 Query: 294 LLRQATYTTARLGSFRVLTNKAIEAN---DGRPLPLVQKAFIGLTAGAIGACVGSPADLA 464 + R A L ++ ++ + ++AN D P AG + SP D+ Sbjct: 183 VARNAIVNCTELVTYDLIKDTLLKANLMTDDLPCHFTS----AFGAGFCTTVIASPVDVV 238 Query: 465 LIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYD 644 R + Y +A H + EG A +KG P+ +R S N+ M +Y+ Sbjct: 239 KTRYMNSAL------GQYHSAGHCALTMLRKEGPRAFYKGFMPSFLRLGSWNVVMFVTYE 292 Query: 645 Q 647 Q Sbjct: 293 Q 293
>UCP2_MOUSE (P70406) Mitochondrial uncoupling protein 2 (UCP 2) (UCPH)| Length = 309 Score = 83.2 bits (204), Expect = 6e-16 Identities = 56/190 (29%), Positives = 83/190 (43%), Gaps = 14/190 (7%) Frame = +3 Query: 117 TIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAK--------------TMYAN 254 T+K F+ G + +A + P+D KV++Q+ S V TM Sbjct: 14 TVK-FLGAGTAACIADLITFPLDTAKVRLQIQGESQGLVRTAASAQYRGVLGTILTMVRT 72 Query: 255 EGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIG 434 EG S Y GL AGL RQ ++ + R+G + + K + + G T GA+ Sbjct: 73 EGPRSLYNGLVAGLQRQMSFASVRIGLYDSV--KQFYTKGSEHAGIGSRLLAGSTTGALA 130 Query: 435 ACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMS 614 V P D+ +R QA + A R Y++ A I +EG+ LWKG P V R Sbjct: 131 VAVAQPTDVVKVRFQAQAR--AGGGRRYQSTVEAYKTIAREEGIRGLWKGTSPNVARNAI 188 Query: 615 LNMGMLASYD 644 +N L +YD Sbjct: 189 VNCAELVTYD 198 Score = 62.4 bits (150), Expect = 1e-09 Identities = 50/181 (27%), Positives = 77/181 (42%), Gaps = 11/181 (6%) Frame = +3 Query: 138 GGASGMLATCVIQPIDMIKVKIQL----GEG----SAAQVAKTMYANEGLGSFYKGLSAG 293 G +G LA V QP D++KV+ Q G G S + KT+ EG+ +KG S Sbjct: 123 GSTTGALAVAVAQPTDVVKVRFQAQARAGGGRRYQSTVEAYKTIAREEGIRGLWKGTSPN 182 Query: 294 LLRQATYTTARLGSFRVLTNKAIEAN---DGRPLPLVQKAFIGLTAGAIGACVGSPADLA 464 + R A A L ++ ++ + ++AN D P AG + SP D+ Sbjct: 183 VARNAIVNCAELVTYDLIKDTLLKANLMTDDLPCHFTS----AFGAGFCTTVIASPVDVV 238 Query: 465 LIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYD 644 R + Y +A H + EG A +KG P+ +R S N+ M +Y+ Sbjct: 239 KTRYMNSAL------GQYHSAGHCALTMLRKEGPRAFYKGFMPSFLRLGSWNVVMFVTYE 292 Query: 645 Q 647 Q Sbjct: 293 Q 293
>UCP2_CANFA (Q9N2J1) Mitochondrial uncoupling protein 2 (UCP 2)| Length = 309 Score = 83.2 bits (204), Expect = 6e-16 Identities = 58/190 (30%), Positives = 85/190 (44%), Gaps = 14/190 (7%) Frame = +3 Query: 117 TIKPFVNGGASGMLATCVIQPIDMIKVKIQL-----GEGSAAQVAK---------TMYAN 254 T+K F+ G + +A + P+D KV++Q+ G AA A+ TM Sbjct: 14 TVK-FLGAGTAACIADLITFPLDTAKVRLQIQGERQGPVRAAASAQYRGVLCTILTMVRT 72 Query: 255 EGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIG 434 EG S Y GL AGL RQ ++ + R+G + + K + + G T GA+ Sbjct: 73 EGPRSLYSGLVAGLQRQMSFASVRIGLYDSV--KQFYTKGSEHAGIGSRLLAGSTTGALA 130 Query: 435 ACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMS 614 V P D+ +R QA + A R Y++ A I +EG LWKG P V R Sbjct: 131 VAVAQPTDVVKVRFQAQAR--AGSGRRYQSTVDAYKTIAREEGFRGLWKGTSPNVARNAI 188 Query: 615 LNMGMLASYD 644 +N L +YD Sbjct: 189 VNCAELVTYD 198 Score = 62.0 bits (149), Expect = 2e-09 Identities = 50/181 (27%), Positives = 75/181 (41%), Gaps = 11/181 (6%) Frame = +3 Query: 138 GGASGMLATCVIQPIDMIKVKIQL----GEG----SAAQVAKTMYANEGLGSFYKGLSAG 293 G +G LA V QP D++KV+ Q G G S KT+ EG +KG S Sbjct: 123 GSTTGALAVAVAQPTDVVKVRFQAQARAGSGRRYQSTVDAYKTIAREEGFRGLWKGTSPN 182 Query: 294 LLRQATYTTARLGSFRVLTNKAIEAN---DGRPLPLVQKAFIGLTAGAIGACVGSPADLA 464 + R A A L ++ ++ + ++AN D P AG + SP D+ Sbjct: 183 VARNAIVNCAELVTYDLIKDALLKANLMTDDLPCHFTS----AFGAGFCTTVIASPVDVV 238 Query: 465 LIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYD 644 R + Y +A H + EG A +KG P+ +R S N+ M +Y+ Sbjct: 239 KTRYMNSAL------GQYSSAGHCALTMLQKEGPRAFYKGFMPSFLRLGSWNVVMFVTYE 292 Query: 645 Q 647 Q Sbjct: 293 Q 293
>UCP3_MOUSE (P56501) Mitochondrial uncoupling protein 3 (UCP 3)| Length = 308 Score = 82.8 bits (203), Expect = 8e-16 Identities = 56/190 (29%), Positives = 84/190 (44%), Gaps = 14/190 (7%) Frame = +3 Query: 117 TIKPFVNGGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAK---------TMYANEGLG 266 T+ F+ G + A + P+D KV++Q+ GE AQ + TM EG Sbjct: 13 TVVKFLGAGTAACFADLLTFPLDTAKVRLQIQGENPGAQSVQYRGVLGTILTMVRTEGPR 72 Query: 267 SFYKGLSAGLLRQATYTTARLGSF----RVLTNKAIEANDGRPLPLVQKAFIGLTAGAIG 434 S Y GL AGL RQ ++ + R+G + + T K + + + + G T GA+ Sbjct: 73 SPYSGLVAGLHRQMSFASIRIGLYDSVKQFYTPKGADHSS-----VAIRILAGCTTGAMA 127 Query: 435 ACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMS 614 P D+ +R QA L R Y+ A I +EGV LWKG P + R Sbjct: 128 VTCAQPTDVVKVRFQAMIRLGTGGERKYRGTMDAYRTIAREEGVRGLWKGTWPNITRNAI 187 Query: 615 LNMGMLASYD 644 +N + +YD Sbjct: 188 VNCAEMVTYD 197 Score = 62.8 bits (151), Expect = 9e-10 Identities = 49/183 (26%), Positives = 79/183 (43%), Gaps = 13/183 (7%) Frame = +3 Query: 138 GGASGMLATCVIQPIDMIKVKIQ----LGEGSAAQVAKTMYA------NEGLGSFYKGLS 287 G +G +A QP D++KV+ Q LG G + TM A EG+ +KG Sbjct: 120 GCTTGAMAVTCAQPTDVVKVRFQAMIRLGTGGERKYRGTMDAYRTIAREEGVRGLWKGTW 179 Query: 288 AGLLRQATYTTARLGSFRVLTNKAIEAN---DGRPLPLVQKAFIGLTAGAIGACVGSPAD 458 + R A A + ++ ++ K +E++ D P V AG V SP D Sbjct: 180 PNITRNAIVNCAEMVTYDIIKEKLLESHLFTDNFPCHFVS----AFGAGFCATVVASPVD 235 Query: 459 LALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLAS 638 + R A Y++ H + ++ A EG A +KG P+ +R + N+ M + Sbjct: 236 VVKTRYMN------APLGRYRSPLHCMLKMVAQEGPTAFYKGFVPSFLRLGAWNVMMFVT 289 Query: 639 YDQ 647 Y+Q Sbjct: 290 YEQ 292
>UCP2_HUMAN (P55851) Mitochondrial uncoupling protein 2 (UCP 2) (UCPH)| Length = 309 Score = 82.8 bits (203), Expect = 8e-16 Identities = 56/190 (29%), Positives = 83/190 (43%), Gaps = 14/190 (7%) Frame = +3 Query: 117 TIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKT--------------MYAN 254 T+K F+ G + +A + P+D KV++Q+ S V T M Sbjct: 14 TVK-FLGAGTAACIADLITFPLDTAKVRLQIQGESQGPVRATASAQYRGVMGTILTMVRT 72 Query: 255 EGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIG 434 EG S Y GL AGL RQ ++ + R+G + + K + + G T GA+ Sbjct: 73 EGPRSLYNGLVAGLQRQMSFASVRIGLYDSV--KQFYTKGSEHASIGSRLLAGSTTGALA 130 Query: 435 ACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMS 614 V P D+ +R QA + A R Y++ +A I +EG LWKG P V R Sbjct: 131 VAVAQPTDVVKVRFQAQAR--AGGGRRYQSTVNAYKTIAREEGFRGLWKGTSPNVARNAI 188 Query: 615 LNMGMLASYD 644 +N L +YD Sbjct: 189 VNCAELVTYD 198 Score = 61.2 bits (147), Expect = 3e-09 Identities = 50/181 (27%), Positives = 75/181 (41%), Gaps = 11/181 (6%) Frame = +3 Query: 138 GGASGMLATCVIQPIDMIKVKIQL----GEG----SAAQVAKTMYANEGLGSFYKGLSAG 293 G +G LA V QP D++KV+ Q G G S KT+ EG +KG S Sbjct: 123 GSTTGALAVAVAQPTDVVKVRFQAQARAGGGRRYQSTVNAYKTIAREEGFRGLWKGTSPN 182 Query: 294 LLRQATYTTARLGSFRVLTNKAIEAN---DGRPLPLVQKAFIGLTAGAIGACVGSPADLA 464 + R A A L ++ ++ + ++AN D P AG + SP D+ Sbjct: 183 VARNAIVNCAELVTYDLIKDALLKANLMTDDLPCHFTS----AFGAGFCTTVIASPVDVV 238 Query: 465 LIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYD 644 R + Y +A H + EG A +KG P+ +R S N+ M +Y+ Sbjct: 239 KTRYMNSAL------GQYSSAGHCALTMLQKEGPRAFYKGFMPSFLRLGSWNVVMFVTYE 292 Query: 645 Q 647 Q Sbjct: 293 Q 293
>UCP2_BRARE (Q9W720) Mitochondrial uncoupling protein 2 (UCP 2)| Length = 310 Score = 82.8 bits (203), Expect = 8e-16 Identities = 57/191 (29%), Positives = 87/191 (45%), Gaps = 15/191 (7%) Frame = +3 Query: 117 TIKPFVNGGASGMLATCVIQPIDMIKVKIQL-GEGSAAQ--------------VAKTMYA 251 T+K F+ G + +A P+D KV++Q+ GE A+ TM Sbjct: 14 TVK-FIGAGTAACIADLFTFPLDTAKVRLQIQGENKASTNMGRGPVKYRGVFGTISTMVR 72 Query: 252 NEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAI 431 EG S Y GL AGL RQ ++ + R+G + + + +D + + G T GA+ Sbjct: 73 VEGPRSLYSGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSDHAGIG--SRLMAGCTTGAM 130 Query: 432 GACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAM 611 V P D+ +R QA + A++R H + A I +EG LWKG GP + R Sbjct: 131 AVAVAQPTDVLKVRFQAQVSAGASKRYH--STMDAYRTIAKEEGFRGLWKGTGPNITRNA 188 Query: 612 SLNMGMLASYD 644 +N L +YD Sbjct: 189 IVNCTELVTYD 199 Score = 49.7 bits (117), Expect = 8e-06 Identities = 42/181 (23%), Positives = 76/181 (41%), Gaps = 11/181 (6%) Frame = +3 Query: 138 GGASGMLATCVIQPIDMIKVKIQ--LGEGSAAQVAKTMYA------NEGLGSFYKGLSAG 293 G +G +A V QP D++KV+ Q + G++ + TM A EG +KG Sbjct: 124 GCTTGAMAVAVAQPTDVLKVRFQAQVSAGASKRYHSTMDAYRTIAKEEGFRGLWKGTGPN 183 Query: 294 LLRQATYTTARLGSFRVLTNKAIEAN---DGRPLPLVQKAFIGLTAGAIGACVGSPADLA 464 + R A L ++ ++ + ++++ D P AG + SP D+ Sbjct: 184 ITRNAIVNCTELVTYDLIKDALLKSSLMTDDLPCHFTS----AFGAGFCTTIIASPVDVV 239 Query: 465 LIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYD 644 R + + Y +A + + +G A +KG P+ +R S N+ M +Y+ Sbjct: 240 KTRYMNSA------QGQYSSALNCAVAMLTKKGPKAFFKGFMPSFLRLGSWNVVMFVTYE 293 Query: 645 Q 647 Q Sbjct: 294 Q 294
>UCP1_HUMAN (P25874) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 307 Score = 82.4 bits (202), Expect = 1e-15 Identities = 53/180 (29%), Positives = 85/180 (47%), Gaps = 10/180 (5%) Frame = +3 Query: 135 NGGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAK---------TMYANEGLGSFYKGL 284 + G + LA + P+D KV++Q+ GE + V + + EG Y GL Sbjct: 19 SAGIAACLADVITFPLDTAKVRLQVQGECPTSSVIRYKGVLGTITAVVKTEGRMKLYSGL 78 Query: 285 SAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLA 464 AGL RQ + + R+G + + + P L K GLT G + +G P ++ Sbjct: 79 PAGLQRQISSASLRIGLYDTVQEFLTAGKETAP-SLGSKILAGLTTGGVAVFIGQPTEVV 137 Query: 465 LIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYD 644 +R+QA S L + R Y ++A I EG+ LWKG P ++R++ +N L +YD Sbjct: 138 KVRLQAQSHLHGIKPR-YTGTYNAYRIIATTEGLTGLWKGTTPNLMRSVIINCTELVTYD 196 Score = 49.7 bits (117), Expect = 8e-06 Identities = 50/216 (23%), Positives = 89/216 (41%), Gaps = 30/216 (13%) Frame = +3 Query: 90 AAAPTGVWKTIKPFVNGG---------------ASGMLATCVIQPIDMIKVKIQL----- 209 A+ G++ T++ F+ G +G +A + QP +++KV++Q Sbjct: 89 ASLRIGLYDTVQEFLTAGKETAPSLGSKILAGLTTGGVAVFIGQPTEVVKVRLQAQSHLH 148 Query: 210 -------GEGSAAQVAKTMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEA 368 G +A ++ T EGL +KG + L+R L ++ ++ ++ Sbjct: 149 GIKPRYTGTYNAYRIIAT---TEGLTGLWKGTTPNLMRSVIINCTELVTYDLMKEAFVKN 205 Query: 369 N---DGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHAL 539 N D P LV L AG + SP D+ R P Q YK+ + Sbjct: 206 NILADDVPCHLVS----ALIAGFCATAMSSPVDVVKTRF---INSPPGQ---YKSVPNCA 255 Query: 540 YRITADEGVLALWKGAGPTVVRAMSLNMGMLASYDQ 647 ++ +EG A +KG P+ +R S N+ M ++Q Sbjct: 256 MKVFTNEGPTAFFKGLVPSFLRLGSWNVIMFVCFEQ 291 Score = 33.1 bits (74), Expect = 0.76 Identities = 21/71 (29%), Positives = 33/71 (46%), Gaps = 4/71 (5%) Frame = +3 Query: 147 SGMLATCVIQPIDMIKVK-IQLGEG---SAAQVAKTMYANEGLGSFYKGLSAGLLRQATY 314 +G AT + P+D++K + I G S A ++ NEG +F+KGL LR ++ Sbjct: 222 AGFCATAMSSPVDVVKTRFINSPPGQYKSVPNCAMKVFTNEGPTAFFKGLVPSFLRLGSW 281 Query: 315 TTARLGSFRVL 347 F L Sbjct: 282 NVIMFVCFEQL 292
>UCP3_PIG (O97649) Mitochondrial uncoupling protein 3 (UCP 3)| Length = 308 Score = 82.0 bits (201), Expect = 1e-15 Identities = 56/190 (29%), Positives = 84/190 (44%), Gaps = 14/190 (7%) Frame = +3 Query: 117 TIKPFVNGGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAK---------TMYANEGLG 266 T + G + A + P+D KV++Q+ GE AA+ A+ TM NEG Sbjct: 13 TAVKLLGAGTAACFADLLTFPLDTAKVRLQIQGENQAARSAQYRGVLGTILTMVRNEGPR 72 Query: 267 SFYKGLSAGLLRQATYTTARLGSF----RVLTNKAIEANDGRPLPLVQKAFIGLTAGAIG 434 S Y GL AGL RQ ++ + R+G + ++ T K + + + + G T GA+ Sbjct: 73 SPYNGLVAGLQRQMSFASIRIGLYDSVKQLYTPKGSDHSS-----ITTRILAGCTTGAMA 127 Query: 435 ACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMS 614 P D+ +R QA R Y A I +EGV LWKG P + R Sbjct: 128 VTCAQPTDVVKVRFQASIHAGPRSNRKYSGTMDAYRTIAREEGVRGLWKGILPNITRNAI 187 Query: 615 LNMGMLASYD 644 +N + +YD Sbjct: 188 VNCAEMVTYD 197 Score = 59.7 bits (143), Expect = 8e-09 Identities = 50/183 (27%), Positives = 78/183 (42%), Gaps = 13/183 (7%) Frame = +3 Query: 138 GGASGMLATCVIQPIDMIKVKIQL----GEGSAAQVAKTMYA------NEGLGSFYKGLS 287 G +G +A QP D++KV+ Q G S + + TM A EG+ +KG+ Sbjct: 120 GCTTGAMAVTCAQPTDVVKVRFQASIHAGPRSNRKYSGTMDAYRTIAREEGVRGLWKGIL 179 Query: 288 AGLLRQATYTTARLGSFRVLTNKAIEAN---DGRPLPLVQKAFIGLTAGAIGACVGSPAD 458 + R A A + ++ V+ K ++ + D P V AG V SP D Sbjct: 180 PNITRNAIVNCAEMVTYDVIKEKVLDYHLLTDNLPCHFVS----AFGAGFCATVVASPVD 235 Query: 459 LALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLAS 638 + R P Q Y+N + ++ EG A +KG P+ +R S N+ M S Sbjct: 236 VVKTRYMNS---PPGQ---YQNPLDCMLKMVTQEGPTAFYKGFTPSFLRLGSWNVVMFVS 289 Query: 639 YDQ 647 Y+Q Sbjct: 290 YEQ 292 Score = 29.6 bits (65), Expect = 8.3 Identities = 19/81 (23%), Positives = 32/81 (39%) Frame = +3 Query: 417 TAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPT 596 TA + P D A +R+Q AA+ Y+ + + +EG + + G Sbjct: 22 TAACFADLLTFPLDTAKVRLQIQGENQAARSAQYRGVLGTILTMVRNEGPRSPYNGLVAG 81 Query: 597 VVRAMSLNMGMLASYDQSVEL 659 + R MS + YD +L Sbjct: 82 LQRQMSFASIRIGLYDSVKQL 102
>UCP1_MESAU (P04575) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 306 Score = 82.0 bits (201), Expect = 1e-15 Identities = 51/180 (28%), Positives = 85/180 (47%), Gaps = 10/180 (5%) Frame = +3 Query: 135 NGGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAK---------TMYANEGLGSFYKGL 284 + G + LA + P+D KV++Q+ GEG + + T+ EGL Y GL Sbjct: 18 SAGVAACLADIITFPLDTAKVRLQIQGEGQISSTIRYKGVLGTITTLAKTEGLPKLYSGL 77 Query: 285 SAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLA 464 AG+ RQ ++ + R+G + + + + P L + GL G + +G P ++ Sbjct: 78 PAGIQRQISFASLRIGLYDTV-QEYFSSGKETPPTLGNRISAGLMTGGVAVFIGQPTEVV 136 Query: 465 LIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYD 644 +R+QA S L + R Y ++A I E LWKG P ++R + +N L +YD Sbjct: 137 KVRLQAQSHLHGIKPR-YTGTYNAYRIIATTESFSTLWKGTTPNLLRNVIINCVELVTYD 195
>UCP1_DICGR (Q8K404) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 307 Score = 81.6 bits (200), Expect = 2e-15 Identities = 53/185 (28%), Positives = 87/185 (47%), Gaps = 10/185 (5%) Frame = +3 Query: 120 IKPFVNGGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAK---------TMYANEGLGS 269 +K F + G S LA + P+D KV++Q+ GEG + + T+ EG Sbjct: 15 VKTF-SAGISACLADIITFPLDTAKVRLQIQGEGQTSSTIRYKGVLGTITTLAKTEGWPK 73 Query: 270 FYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGS 449 Y GL AG+ RQ ++ + R+G + + + + P L + GL G + +G Sbjct: 74 LYSGLPAGIQRQISFASLRIGLYDTV-QEYFSSGKETPPTLGNRISAGLMTGGVAVFIGQ 132 Query: 450 PADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGM 629 P ++ +R+QA S L + R Y ++A I E LWKG P ++R + +N Sbjct: 133 PTEVVKVRLQAQSHLHGIKPR-YTGTYNAYRIIATTESFSTLWKGTTPNLMRNVIINRTE 191 Query: 630 LASYD 644 L +YD Sbjct: 192 LVTYD 196
>UCP3_RAT (P56499) Mitochondrial uncoupling protein 3 (UCP 3)| Length = 308 Score = 81.3 bits (199), Expect = 2e-15 Identities = 55/190 (28%), Positives = 83/190 (43%), Gaps = 14/190 (7%) Frame = +3 Query: 117 TIKPFVNGGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAK---------TMYANEGLG 266 T+ F+ G + A + P+D KV++Q+ GE Q + TM EG Sbjct: 13 TVVKFLGAGTAACFADLLTFPLDTAKVRLQIQGENPGVQSVQYRGVLGTILTMVRTEGPR 72 Query: 267 SFYKGLSAGLLRQATYTTARLGSF----RVLTNKAIEANDGRPLPLVQKAFIGLTAGAIG 434 S Y GL AGL RQ ++ + R+G + + T K + + + + G T GA+ Sbjct: 73 SPYSGLVAGLHRQMSFASIRIGLYDSVKQFYTPKGTDHSS-----VAIRILAGCTTGAMA 127 Query: 435 ACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMS 614 P D+ +R QA L R Y+ A I +EGV LWKG P + R Sbjct: 128 VTCAQPTDVVKVRFQAMIRLGTGGERKYRGTMDAYRTIAREEGVRGLWKGTWPNITRNAI 187 Query: 615 LNMGMLASYD 644 +N + +YD Sbjct: 188 VNCAEMVTYD 197 Score = 63.9 bits (154), Expect = 4e-10 Identities = 50/183 (27%), Positives = 79/183 (43%), Gaps = 13/183 (7%) Frame = +3 Query: 138 GGASGMLATCVIQPIDMIKVKIQ----LGEGSAAQVAKTMYA------NEGLGSFYKGLS 287 G +G +A QP D++KV+ Q LG G + TM A EG+ +KG Sbjct: 120 GCTTGAMAVTCAQPTDVVKVRFQAMIRLGTGGERKYRGTMDAYRTIAREEGVRGLWKGTW 179 Query: 288 AGLLRQATYTTARLGSFRVLTNKAIEAN---DGRPLPLVQKAFIGLTAGAIGACVGSPAD 458 + R A A + ++ ++ K ++++ D P V AG V SP D Sbjct: 180 PNITRNAIVNCAEMVTYDIIKEKLLDSHLFTDNFPCHFVS----AFGAGFCATVVASPVD 235 Query: 459 LALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLAS 638 + R A Y++ H + R+ A EG A +KG P+ +R S N+ M + Sbjct: 236 VVKTRYMN------APPGRYRSPLHCMLRMVAQEGPTAFYKGFMPSFLRLGSWNVMMFVT 289 Query: 639 YDQ 647 Y+Q Sbjct: 290 YEQ 292
>UCP2_CYPCA (Q9W725) Mitochondrial uncoupling protein 2 (UCP 2)| Length = 310 Score = 80.1 bits (196), Expect = 5e-15 Identities = 55/191 (28%), Positives = 83/191 (43%), Gaps = 15/191 (7%) Frame = +3 Query: 117 TIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQV---------------AKTMYA 251 T+K F+ G + +A P+D KV++Q+ S V TM Sbjct: 14 TVK-FIGAGTAACIADLFTFPLDTAKVRLQIQGESKIPVNTGHGPVKYRGVFGTISTMVR 72 Query: 252 NEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAI 431 EG S Y GL AGL RQ ++ + R+G + + K + + + G T GA+ Sbjct: 73 VEGPRSLYSGLVAGLQRQMSFASVRIGLYDSV--KQFYTKGSEHVGIGSRLMAGCTTGAM 130 Query: 432 GACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAM 611 + P D+ +R QA ++ A +R H A I +EG LWKG GP + R Sbjct: 131 AVALAQPTDVVKVRFQAQNSAGANKRYH--GTMDAYRTIAKEEGFRGLWKGTGPNITRNA 188 Query: 612 SLNMGMLASYD 644 +N L +YD Sbjct: 189 IVNCTELVTYD 199 Score = 49.3 bits (116), Expect = 1e-05 Identities = 41/181 (22%), Positives = 74/181 (40%), Gaps = 11/181 (6%) Frame = +3 Query: 138 GGASGMLATCVIQPIDMIKVKIQLGEGSAAQ--------VAKTMYANEGLGSFYKGLSAG 293 G +G +A + QP D++KV+ Q + A +T+ EG +KG Sbjct: 124 GCTTGAMAVALAQPTDVVKVRFQAQNSAGANKRYHGTMDAYRTIAKEEGFRGLWKGTGPN 183 Query: 294 LLRQATYTTARLGSFRVLTNKAIEAN---DGRPLPLVQKAFIGLTAGAIGACVGSPADLA 464 + R A L ++ ++ + ++++ D P AG + SP D+ Sbjct: 184 ITRNAIVNCTELVTYDLIKDALLKSSLMTDDLPCHFTS----AFGAGFCTTVIASPVDVV 239 Query: 465 LIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYD 644 R ++ P Y +A + + EG A +KG P+ +R S N+ M +Y+ Sbjct: 240 KTRYM--NSAPG----QYCSALNCAVAMLTKEGPKAFYKGFMPSFLRLGSWNVVMFVTYE 293 Query: 645 Q 647 Q Sbjct: 294 Q 294
>UCP1_CANFA (Q9GMZ1) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 309 Score = 78.2 bits (191), Expect = 2e-14 Identities = 50/175 (28%), Positives = 82/175 (46%), Gaps = 12/175 (6%) Frame = +3 Query: 156 LATCVIQPIDMIKVKIQL---GEGSAAQVAK---------TMYANEGLGSFYKGLSAGLL 299 LA + P+D KV++Q+ G+G + + T+ EGL Y GL AGL Sbjct: 26 LADMITFPLDTAKVRLQIQGEGQGQPPRAPRYRGVLGTVATLARTEGLQKLYSGLPAGLQ 85 Query: 300 RQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQ 479 RQ + + R+G + + + + G L + G+ G +G P ++ +R+Q Sbjct: 86 RQVGFASLRIGLYDSV-REWLSPGQGAAASLGSRISAGVMTGGAAVFIGQPTEVVKVRLQ 144 Query: 480 ADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYD 644 A S L + R Y ++A I EG+ LWKG P ++R + +N L +YD Sbjct: 145 AQSHLHGRKPR-YTGTYNAYRIIATTEGLTGLWKGTTPNLMRNVIINCTELVTYD 198
>UCP4_HUMAN (O95847) Mitochondrial uncoupling protein 4 (UCP 4) (Solute carrier| family 25 member 27) Length = 323 Score = 77.4 bits (189), Expect = 3e-14 Identities = 51/212 (24%), Positives = 95/212 (44%), Gaps = 19/212 (8%) Frame = +3 Query: 66 MADAKQQQAAAP-TGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQL-GEGSAAQV-- 233 M+ ++++ P T W F+ G + +A P+D+ K ++Q+ GE + A++ Sbjct: 1 MSVPEEEERLLPLTQRWPRASKFLLSGCAATVAELATFPLDLTKTRLQMQGEAALARLGD 60 Query: 234 --------------AKTMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEAN 371 A + EG ++G++ + R Y+ R+ ++ L + Sbjct: 61 GARESAPYRGMVRTALGIIEEEGFLKLWQGVTPAIYRHVVYSGGRMVTYEHLREVVFGKS 120 Query: 372 DGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRR-HYKNAFHALYRI 548 + PL + G+ AG IG + +P DL ++MQ + + ++ HA +I Sbjct: 121 EDEHYPLWKSVIGGMMAGVIGQFLANPTDLVKVQMQMEGKRKLEGKPLRFRGVHHAFAKI 180 Query: 549 TADEGVLALWKGAGPTVVRAMSLNMGMLASYD 644 A+ G+ LW G P + RA +NMG L +YD Sbjct: 181 LAEGGIRGLWAGWVPNIQRAALVNMGDLTTYD 212 Score = 46.2 bits (108), Expect = 9e-05 Identities = 45/217 (20%), Positives = 91/217 (41%), Gaps = 17/217 (7%) Frame = +3 Query: 60 KEMADAKQQQAAAPTGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAK 239 +E+ K + P +WK++ + G +G++ + P D++KV++Q+ EG K Sbjct: 113 REVVFGKSEDEHYP--LWKSV---IGGMMAGVIGQFLANPTDLVKVQMQM-EGKRKLEGK 166 Query: 240 TM------------YANEGLGSFYKGL-----SAGLLRQATYTTARLGSFRVLTNKAIEA 368 + A G+ + G A L+ TT ++ N +E Sbjct: 167 PLRFRGVHHAFAKILAEGGIRGLWAGWVPNIQRAALVNMGDLTTYDTVKHYLVLNTPLED 226 Query: 369 NDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRI 548 N ++ L +G + + +G+PAD+ R+ + YK++ L + Sbjct: 227 N------IMTHGLSSLCSGLVASILGTPADVIKSRIMNQPRDKQGRGLLYKSSTDCLIQA 280 Query: 549 TADEGVLALWKGAGPTVVRAMSLNMGMLASYDQSVEL 659 EG ++L+KG P+ +R +M +Y++ E+ Sbjct: 281 VQGEGFMSLYKGFLPSWLRMTPWSMVFWLTYEKIREM 317 Score = 35.4 bits (80), Expect = 0.15 Identities = 28/114 (24%), Positives = 46/114 (40%), Gaps = 13/114 (11%) Frame = +3 Query: 357 AIEANDGRPLPLVQ------KAFIGLTAGAIGACVGSPADLALIR--MQADSTLP----- 497 ++ + R LPL Q K + A + P DL R MQ ++ L Sbjct: 2 SVPEEEERLLPLTQRWPRASKFLLSGCAATVAELATFPLDLTKTRLQMQGEAALARLGDG 61 Query: 498 AAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYDQSVEL 659 A + Y+ I +EG L LW+G P + R + + G + +Y+ E+ Sbjct: 62 ARESAPYRGMVRTALGIIEEEGFLKLWQGVTPAIYRHVVYSGGRMVTYEHLREV 115
>UCP1_RABIT (P14271) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 306 Score = 76.3 bits (186), Expect = 8e-14 Identities = 55/184 (29%), Positives = 88/184 (47%), Gaps = 14/184 (7%) Frame = +3 Query: 135 NGGASGMLATCVIQPIDMIKVKIQL-GE-------------GSAAQVAKTMYANEGLGSF 272 + G + LA + P+D KV+ Q+ GE G+ +AKT EG Sbjct: 19 SAGVAACLADVITFPLDTAKVRQQIQGEFPITSGIRYKGVLGTITTLAKT----EGPLKL 74 Query: 273 YKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSP 452 Y GL AGL RQ ++ + R+G + + + + + P L K GLT G + +G P Sbjct: 75 YSGLPAGLQRQISFASLRIGLYDTV-QEFFTSGEETP-SLGSKISAGLTTGGVAVFIGQP 132 Query: 453 ADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGML 632 ++ +R+QA S L + R Y ++A I E + +LWKG P ++R + +N L Sbjct: 133 TEVVKVRLQAQSHLHGLKPR-YTGTYNAYRIIATTESLTSLWKGTTPNLLRNVIINCTEL 191 Query: 633 ASYD 644 +YD Sbjct: 192 VTYD 195 Score = 35.4 bits (80), Expect = 0.15 Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 4/84 (4%) Frame = +3 Query: 129 FVNGGASGMLATCVIQPIDMIKVK-IQLGEGSAAQV---AKTMYANEGLGSFYKGLSAGL 296 FV+ +G T + P+D++K + I G A V A TM+ EG +F+KG Sbjct: 215 FVSALIAGFCTTLLSSPVDVVKTRFINSPPGQYASVPNCAMTMFTKEGPTAFFKGFVPSF 274 Query: 297 LRQATYTTARLGSFRVLTNKAIEA 368 LR ++ F L + + + Sbjct: 275 LRLGSWNVIMFVCFEKLKGELMRS 298 Score = 32.0 bits (71), Expect = 1.7 Identities = 20/82 (24%), Positives = 29/82 (35%) Frame = +3 Query: 399 KAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALW 578 K F A + + P D A +R Q P YK + + EG L L+ Sbjct: 16 KIFSAGVAACLADVITFPLDTAKVRQQIQGEFPITSGIRYKGVLGTITTLAKTEGPLKLY 75 Query: 579 KGAGPTVVRAMSLNMGMLASYD 644 G + R +S + YD Sbjct: 76 SGLPAGLQRQISFASLRIGLYD 97
>OAC1_YEAST (P32332) Mitochondrial oxaloacetate transport protein| (Mitochondrial carrier protein PMT) Length = 324 Score = 75.9 bits (185), Expect = 1e-13 Identities = 60/196 (30%), Positives = 95/196 (48%), Gaps = 18/196 (9%) Frame = +3 Query: 72 DAKQQQAAAPTGVWKTIK--PFVNGGASGMLATCVIQPIDMIKVKIQL-GE--GSAAQVA 236 ++KQ + T K K FV GG + +A V PI++IK+++QL GE SAA+V Sbjct: 5 NSKQDKQIEKTAAQKISKFGSFVAGGLAACIAVTVTNPIELIKIRMQLQGEMSASAAKVY 64 Query: 237 K-------TMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEA--NDGRPLP 389 K ++ NEG+ KGL+A + Q +RLG + + + + D P Sbjct: 65 KNPIQGMAVIFKNEGIKGLQKGLNAAYIYQIGLNGSRLGFYEPIRSSLNQLFFPDQEPHK 124 Query: 390 LVQ---KAFIGLTAGAIGACVGSPADLALIRMQADST-LPAAQRRHYKNAFHALYRITAD 557 + F G +G IGA +GSP L R+Q+ S + ++ HY ++ L I Sbjct: 125 VQSVGVNVFSGAASGIIGAVIGSPLFLVKTRLQSYSEFIKIGEQTHYTGVWNGLVTIFKT 184 Query: 558 EGVLALWKGAGPTVVR 605 EGV L++G ++R Sbjct: 185 EGVKGLFRGIDAAILR 200 Score = 47.8 bits (112), Expect = 3e-05 Identities = 45/189 (23%), Positives = 81/189 (42%), Gaps = 14/189 (7%) Frame = +3 Query: 135 NGGASGMLATCVIQPIDMIKVKIQ-------LGEGS----AAQVAKTMYANEGLGSFYKG 281 +G ASG++ + P+ ++K ++Q +GE + T++ EG+ ++G Sbjct: 134 SGAASGIIGAVIGSPLFLVKTRLQSYSEFIKIGEQTHYTGVWNGLVTIFKTEGVKGLFRG 193 Query: 282 LSAGLLRQATYTTARLGSFRVLTNKAIEAN---DGRPLPLVQKAFIGLTAGAIGACVGSP 452 + A +LR ++ +L + N ++ + DG L L GL A V +P Sbjct: 194 IDAAILRTGAGSSVQLPIYNTAKNILVKNDLMKDGPALHLTASTISGLGV----AVVMNP 249 Query: 453 ADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGML 632 D+ L R+ + YK L + EGV AL+KG V R + L Sbjct: 250 WDVILTRIYNQ------KGDLYKGPIDCLVKTVRIEGVTALYKGFAAQVFRIAPHTIMCL 303 Query: 633 ASYDQSVEL 659 +Q+++L Sbjct: 304 TFMEQTMKL 312 Score = 43.5 bits (101), Expect = 6e-04 Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 4/84 (4%) Frame = +3 Query: 405 FIGLTAGAIGACVG----SPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLA 572 F AG + AC+ +P +L IRMQ + A+ + YKN + I +EG+ Sbjct: 23 FGSFVAGGLAACIAVTVTNPIELIKIRMQLQGEMSASAAKVYKNPIQGMAVIFKNEGIKG 82 Query: 573 LWKGAGPTVVRAMSLNMGMLASYD 644 L KG + + LN L Y+ Sbjct: 83 LQKGLNAAYIYQIGLNGSRLGFYE 106
>UCP5_MOUSE (Q9Z2B2) Brain mitochondrial carrier protein 1 (BMCP-1)| (Mitochondrial uncoupling protein 5) (UCP 5) (Solute carrier family 25 member 14) Length = 325 Score = 74.7 bits (182), Expect = 2e-13 Identities = 53/187 (28%), Positives = 87/187 (46%), Gaps = 13/187 (6%) Frame = +3 Query: 123 KPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKT-------------MYANEGL 263 KPFV GG + ++A P+D+ K ++Q+ +G + V +Y EG+ Sbjct: 42 KPFVYGGLASIVAEFGTFPVDLTKTRLQV-QGQSIDVRFKEIKYRGMFHALFRIYKEEGI 100 Query: 264 GSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACV 443 + Y G++ LLRQA+Y T ++G ++ L +E + L + G+ +G I + + Sbjct: 101 LALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLI--NMICGVVSGVISSTI 158 Query: 444 GSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNM 623 +P D+ IRMQA +L + + I EG LW+G PT RA + Sbjct: 159 ANPTDVLKIRMQAQGSL------FQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVG 212 Query: 624 GMLASYD 644 L YD Sbjct: 213 VELPVYD 219 Score = 50.1 bits (118), Expect = 6e-06 Identities = 40/174 (22%), Positives = 72/174 (41%), Gaps = 4/174 (2%) Frame = +3 Query: 138 GGASGMLATCVIQPIDMIKVKIQ----LGEGSAAQVAKTMYANEGLGSFYKGLSAGLLRQ 305 G SG++++ + P D++K+++Q L +GS +Y EG ++G+ R Sbjct: 148 GVVSGVISSTIANPTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRA 207 Query: 306 ATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQAD 485 A L + + T K + + ++ T G GA +P D+ RM Sbjct: 208 AIVVGVELPVYDI-TKKHLIVSGMLGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQ 266 Query: 486 STLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYDQ 647 + YK + ++ EG AL+KG P +R N+ +Y+Q Sbjct: 267 RAI-VGHVDLYKGTLDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQ 319
>UCP1_BOVIN (P10861) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) (Fragment) Length = 288 Score = 74.7 bits (182), Expect = 2e-13 Identities = 50/180 (27%), Positives = 81/180 (45%), Gaps = 10/180 (5%) Frame = +3 Query: 135 NGGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAK---------TMYANEGLGSFYKGL 284 + G + +A + P+D KV++Q+ GE + + T+ EG Y GL Sbjct: 3 SAGVAACVADIITFPLDTAKVRLQIQGECLISSAIRYKGVLGTIITLAKTEGPVKLYSGL 62 Query: 285 SAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLA 464 AGL RQ + + R+G + + G+ L K GL G + +G P ++ Sbjct: 63 PAGLQRQISLASLRIGLYDTVQEFF---TTGKEASLGSKISAGLMTGGVAVFIGQPTEVV 119 Query: 465 LIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYD 644 +R+QA S L + R Y ++A I EG+ LWKG P + + +N L +YD Sbjct: 120 KVRLQAQSHLHGPKPR-YTGTYNAYRIIATTEGLTGLWKGTSPNLTTNVIINCTELVTYD 178
>UCP5_HUMAN (O95258) Brain mitochondrial carrier protein 1 (BMCP-1)| (Mitochondrial uncoupling protein 5) (UCP 5) (Solute carrier family 25 member 14) Length = 325 Score = 74.3 bits (181), Expect = 3e-13 Identities = 53/186 (28%), Positives = 87/186 (46%), Gaps = 12/186 (6%) Frame = +3 Query: 123 KPFVNGGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAKTMYAN-----------EGLG 266 KPFV GG + ++A P+D+ K ++Q+ G+ A+ + Y EG+ Sbjct: 42 KPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVL 101 Query: 267 SFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVG 446 + Y G++ LLRQA+Y T ++G ++ L +E + L + G+ +G I + + Sbjct: 102 ALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLI--NMICGVVSGVISSTIA 159 Query: 447 SPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMG 626 +P D+ IRMQA +L + + I EG LW+G PT RA + Sbjct: 160 NPTDVLKIRMQAQGSL------FQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGV 213 Query: 627 MLASYD 644 L YD Sbjct: 214 ELPVYD 219 Score = 49.7 bits (117), Expect = 8e-06 Identities = 40/174 (22%), Positives = 72/174 (41%), Gaps = 4/174 (2%) Frame = +3 Query: 138 GGASGMLATCVIQPIDMIKVKIQ----LGEGSAAQVAKTMYANEGLGSFYKGLSAGLLRQ 305 G SG++++ + P D++K+++Q L +GS +Y EG ++G+ R Sbjct: 148 GVVSGVISSTIANPTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRA 207 Query: 306 ATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQAD 485 A L + + T K + + ++ T G GA +P D+ RM Sbjct: 208 AIVVGVELPVYDI-TKKHLILSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQ 266 Query: 486 STLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYDQ 647 + YK + ++ EG AL+KG P +R N+ +Y+Q Sbjct: 267 RAI-VGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQ 319
>ODC_PONPY (Q5RFB7) Mitochondrial 2-oxodicarboxylate carrier (Solute carrier| family 25 member 21) Length = 299 Score = 71.2 bits (173), Expect = 3e-12 Identities = 51/179 (28%), Positives = 84/179 (46%), Gaps = 8/179 (4%) Frame = +3 Query: 132 VNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTM-YANE-------GLGSFYKGLS 287 + G SG+ V+ P +++KV +Q + A+ T+ YA + GL KGL+ Sbjct: 114 IAGLGSGLTEAIVVNPFEVVKVGLQANRNTFAKQPSTVGYARQIIKKEGWGLQGLNKGLT 173 Query: 288 AGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 467 A L R + G + + N I N L ++K IGL +G I + + P D+A Sbjct: 174 ATLGRHGVFNMVYFGFYYNVKNM-IPVNKDPTLEFLRKFGIGLLSGTIASVINIPFDVAK 232 Query: 468 IRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYD 644 R+Q +P + Y+ F + + +EG+LAL+KG P ++R ML Y+ Sbjct: 233 SRIQGPQPVPGEIK--YRTCFKTMATVYQEEGILALYKGLLPKIMRLGPGGAVMLLVYE 289 Score = 40.0 bits (92), Expect = 0.006 Identities = 30/140 (21%), Positives = 62/140 (44%), Gaps = 12/140 (8%) Frame = +3 Query: 123 KPFVNGGASGMLATCVIQPIDMIKVKIQL--------GEGSAAQVAKTMYANEGLGSFYK 278 + V GG++G++ C++ P+D++K + Q+ S + ++ E L FYK Sbjct: 15 RQIVAGGSAGLVEICLMHPLDVVKTRFQIQRCATDPNSYKSLVDSFRMIFQTERLFGFYK 74 Query: 279 GLSAGLLRQATYTTARLGSF----RVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVG 446 G+ +L + + +F ++L ++ P + GL +G A V Sbjct: 75 GILPPILAETPKRAVKFFTFEQYKKLLGYVSLS-------PALTFTIAGLGSGLTEAIVV 127 Query: 447 SPADLALIRMQADSTLPAAQ 506 +P ++ + +QA+ A Q Sbjct: 128 NPFEVVKVGLQANRNTFAKQ 147
>ODC_HUMAN (Q9BQT8) Mitochondrial 2-oxodicarboxylate carrier (Solute carrier| family 25 member 21) Length = 299 Score = 69.3 bits (168), Expect = 1e-11 Identities = 51/179 (28%), Positives = 83/179 (46%), Gaps = 8/179 (4%) Frame = +3 Query: 132 VNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTM-YANE-------GLGSFYKGLS 287 + G SG+ V+ P +++KV +Q + A+ T+ YA + GL KGL+ Sbjct: 114 IAGLGSGLTEAIVVNPFEVVKVGLQANRNTFAEQPSTVGYARQIIKKEGWGLQGLNKGLT 173 Query: 288 AGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 467 A L R + G + + N I N L +K IGL +G I + + P D+A Sbjct: 174 ATLGRHGVFNMVYFGFYYNVKNM-IPVNKDPILEFWRKFGIGLLSGTIASVINIPFDVAK 232 Query: 468 IRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYD 644 R+Q +P + Y+ F + + +EG+LAL+KG P ++R ML Y+ Sbjct: 233 SRIQGPQPVPGEIK--YRTCFKTMATVYQEEGILALYKGLLPKIMRLGPGGAVMLLVYE 289 Score = 43.9 bits (102), Expect = 4e-04 Identities = 32/140 (22%), Positives = 64/140 (45%), Gaps = 12/140 (8%) Frame = +3 Query: 123 KPFVNGGASGMLATCVIQPIDMIKVKIQL--------GEGSAAQVAKTMYANEGLGSFYK 278 + V GG++G++ C++ P+D++K + Q+ S + ++ EGL FYK Sbjct: 15 RQIVAGGSAGLVEICLMHPLDVVKTRFQIQRCATDPNSYKSLVDSFRMIFQMEGLFGFYK 74 Query: 279 GLSAGLLRQATYTTARLGSF----RVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVG 446 G+ +L + + +F ++L ++ P + A GL +G A V Sbjct: 75 GILPPILAETPKRAVKFFTFEQYKKLLGYVSLS-------PALTFAIAGLGSGLTEAIVV 127 Query: 447 SPADLALIRMQADSTLPAAQ 506 +P ++ + +QA+ A Q Sbjct: 128 NPFEVVKVGLQANRNTFAEQ 147
>ODC_MOUSE (Q8BZ09) Mitochondrial 2-oxodicarboxylate carrier (Solute carrier| family 25 member 21) Length = 298 Score = 68.9 bits (167), Expect = 1e-11 Identities = 48/166 (28%), Positives = 80/166 (48%), Gaps = 8/166 (4%) Frame = +3 Query: 132 VNGGASGMLATCVIQPIDMIKVKIQLGEG------SAAQVAKTMYANEGLG--SFYKGLS 287 + G SG+ V+ P +++KV +Q+ S A+ + EGLG KGL+ Sbjct: 113 IAGLGSGLTEAVVVNPFEVVKVGLQVNRNLFKEQPSTFAYARQIIKKEGLGFQGLNKGLT 172 Query: 288 AGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 467 A L R + G + + N I ++ L ++K IG +G +G+ P D+A Sbjct: 173 ATLGRHGIFNMVYFGFYHNVKN-IIPSSKDPTLEFLRKFGIGFVSGTMGSVFNIPFDVAK 231 Query: 468 IRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVR 605 R+Q +P + Y++ F + I +EG+LAL+KG P V+R Sbjct: 232 SRIQGPQPVPGEIK--YRSCFKTMEMIYREEGILALYKGLVPKVMR 275 Score = 40.8 bits (94), Expect = 0.004 Identities = 42/186 (22%), Positives = 78/186 (41%), Gaps = 10/186 (5%) Frame = +3 Query: 114 KTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEG-SAAQVAKT-------MYANEGLGS 269 +T + GG++G++ C++ P+D++K + Q+ + Q +T ++ EGL Sbjct: 11 ETSRQVAAGGSAGLVEICLMHPLDVVKTRFQVQRSVTDPQSYRTVRGSFQMIFRTEGLFG 70 Query: 270 FYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGS 449 FYKG+ +L + + +F + + L + GL +G A V + Sbjct: 71 FYKGIIPPILAETPKRAVKFSTFELYKKFLGYMSLSPGLTFL---IAGLGSGLTEAVVVN 127 Query: 450 PADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGV--LALWKGAGPTVVRAMSLNM 623 P ++ + +Q + L Q + F +I EG+ L KG T+ R NM Sbjct: 128 PFEVVKVGLQVNRNLFKEQ----PSTFAYARQIIKKEGLGFQGLNKGLTATLGRHGIFNM 183 Query: 624 GMLASY 641 Y Sbjct: 184 VYFGFY 189
>SFC1_YEAST (P33303) Succinate/fumarate mitochondrial transporter (Regulator of| acetyl-CoA synthetase activity) Length = 322 Score = 68.6 bits (166), Expect = 2e-11 Identities = 49/181 (27%), Positives = 83/181 (45%), Gaps = 13/181 (7%) Frame = +3 Query: 102 TGVWKTIKPFVNGGASGML-ATCVIQPIDMIKVKIQLGE------------GSAAQVAKT 242 +G+ T FV G +G+ A V+ P++++K+++Q +A A T Sbjct: 105 SGIVSTGNTFVAGVGAGITEAVLVVNPMEVVKIRLQAQHLTPSEPNAGPKYNNAIHAAYT 164 Query: 243 MYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTA 422 + EG+ + Y+G+S RQAT A + L + LP + + IGL + Sbjct: 165 IVKEEGVSALYRGVSLTAARQATNQGANFTVYSKLKEFLQNYHQMDVLPSWETSCIGLIS 224 Query: 423 GAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVV 602 GAIG +P D R+Q D ++ ++ K ++ +EG AL+KG P V+ Sbjct: 225 GAIGPFSNAPLDTIKTRLQKDKSISLEKQSGMKKIITIGAQLLKEEGFRALYKGITPRVM 284 Query: 603 R 605 R Sbjct: 285 R 285 Score = 66.2 bits (160), Expect = 8e-11 Identities = 52/181 (28%), Positives = 78/181 (43%), Gaps = 17/181 (9%) Frame = +3 Query: 114 KTIKPFVN---GGASGMLATCVIQPIDMIKVKIQLGEGSAA----------QVAKTMYAN 254 K P +N GG +G+ P+D IKV++Q+ A + +T+Y Sbjct: 6 KASHPAINLMAGGTAGLFEALCCHPLDTIKVRMQIYRRVAGIEHVKPPGFIKTGRTIYQK 65 Query: 255 EGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFI-GLTAGAI 431 EG + YKGL A ++ R S+ + G + F+ G+ AG Sbjct: 66 EGFLALYKGLGAVVIGIIPKMAIRFSSYEFYRTLLVNKESG--IVSTGNTFVAGVGAGIT 123 Query: 432 GA-CVGSPADLALIRMQADSTLPAAQRR--HYKNAFHALYRITADEGVLALWKGAGPTVV 602 A V +P ++ IR+QA P+ Y NA HA Y I +EGV AL++G T Sbjct: 124 EAVLVVNPMEVVKIRLQAQHLTPSEPNAGPKYNNAIHAAYTIVKEEGVSALYRGVSLTAA 183 Query: 603 R 605 R Sbjct: 184 R 184
>MNCP_OXYFA (P15798) Macronuclear solute carrier homolog CR-MSC| Length = 371 Score = 68.2 bits (165), Expect = 2e-11 Identities = 56/188 (29%), Positives = 82/188 (43%), Gaps = 16/188 (8%) Frame = +3 Query: 129 FVNGGASGMLATCVIQPIDMIKVKIQ-LGEGSAA------------QVAKTMYA-NEGLG 266 F ++ QP+DM++++ Q L EG Q+ + +YA GL Sbjct: 22 FAAANVIALITHAATQPLDMVRIRSQMLQEGKTFSGLGYQKGWYPFQIMEEIYAAGGGLR 81 Query: 267 SFYKGLSAGLLRQATYTTARLGSFRVLTNKAIE--ANDGRPLPLVQKAFIGLTAGAIGAC 440 FY R YTTAR+ +F +K + RP LV +G G I Sbjct: 82 KFYSAFDTFFFRTVCYTTARVTAFGYFYDKVNKDPRRVARPDFLVAAGVLG---GFIAGV 138 Query: 441 VGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLN 620 V +P D+ RMQ D P A RR+Y N L ++ A+EG AL++GAG + ++ Sbjct: 139 VTNPIDIVYNRMQVDELYPQAARRNYSNTIQGLAKV-AEEG--ALFRGAGANGFKLAAIC 195 Query: 621 MGMLASYD 644 M YD Sbjct: 196 SSMTNIYD 203
>BT1_MAIZE (P29518) Protein brittle-1, chloroplast precursor| Length = 436 Score = 68.2 bits (165), Expect = 2e-11 Identities = 46/168 (27%), Positives = 76/168 (45%), Gaps = 6/168 (3%) Frame = +3 Query: 126 PFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKT---MYANEGLGSFYKGLSAGL 296 P V G +G +T P+++IK ++ + + VA + +EG Y+GL+ L Sbjct: 232 PLVAGALAGFASTLCTYPMELIKTRVTIEKDVYDNVAHAFVKILRDEGPSELYRGLTPSL 291 Query: 297 LRQATYTTARLGSFRVLTNKAIEANDGRP---LPLVQKAFIGLTAGAIGACVGSPADLAL 467 + Y ++ L A RP + V IG AGAI + P ++A Sbjct: 292 IGVVPYAACNFYAYETLKRLYRRATGRRPGADVGPVATLLIGSAAGAIASSATFPLEVAR 351 Query: 468 IRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAM 611 +MQ + R+ Y+N HA+Y I EG L++G GP+ ++ M Sbjct: 352 KQMQVGAV---GGRQVYQNVLHAIYCILKKEGAGGLYRGLGPSCIKLM 396
>MNCP_OXYTR (Q27151) Macronuclear solute carrier homolog CR-MSC| Length = 371 Score = 67.4 bits (163), Expect = 4e-11 Identities = 56/188 (29%), Positives = 82/188 (43%), Gaps = 16/188 (8%) Frame = +3 Query: 129 FVNGGASGMLATCVIQPIDMIKVKIQ-LGEGSAA------------QVAKTMYA-NEGLG 266 F ++ QP+DM++++ Q L EG Q+ + +YA GL Sbjct: 22 FAAANVIALITHAATQPLDMVRIRSQMLQEGKTFSGLGYQKGWYPFQIMEEIYAAGGGLR 81 Query: 267 SFYKGLSAGLLRQATYTTARLGSFRVLTNKAIE--ANDGRPLPLVQKAFIGLTAGAIGAC 440 FY R YTTAR+ +F +K + RP LV +G G I Sbjct: 82 KFYSAFDTFFFRTVGYTTARVTAFGYFYDKVNKDPRRVARPDFLVAAGVLG---GFIAGV 138 Query: 441 VGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLN 620 V +P D+ RMQ D P A RR+Y N L ++ A+EG AL++GAG + ++ Sbjct: 139 VTNPIDIVYNRMQVDELYPQAARRNYSNTVQGLAKV-AEEG--ALFRGAGANGFKLAAIC 195 Query: 621 MGMLASYD 644 M YD Sbjct: 196 SSMTNIYD 203
>CMC1_YEAST (P48233) Calcium-binding mitochondrial carrier SAL1 (Suppressor of| AAC2 lethality) Length = 545 Score = 65.5 bits (158), Expect = 1e-10 Identities = 52/176 (29%), Positives = 76/176 (43%), Gaps = 17/176 (9%) Frame = +3 Query: 129 FVNGGASGMLATCVIQPIDMIKVKIQL--------GEGSAAQVAKTMYANEGLGSFYKGL 284 ++ GG +GM A + PID +K ++Q G Q AK M+ GL FY+G+ Sbjct: 351 YIAGGLAGMAAQFSVYPIDTLKFRVQCAPLDTKLKGNNLLFQTAKDMFREGGLRLFYRGV 410 Query: 285 SAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAF---------IGLTAGAIGA 437 + G++ Y LG+F L K A + L L Q +G +G +GA Sbjct: 411 TVGIVGIFPYAALDLGTFSAL-KKWYIAKQAKTLNLPQDQVTLSNLVVLPMGAFSGTVGA 469 Query: 438 CVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVR 605 V P +L R+QA T A Y L + EG L+KG PT+ + Sbjct: 470 SVVYPINLLRTRLQAQGTY--AHPYVYNGFKDVLLKTLEREGYQGLFKGLVPTLAK 523
>YG2O_YEAST (P53257) Putative mitochondrial carrier YGR096W| Length = 314 Score = 63.2 bits (152), Expect = 7e-10 Identities = 58/189 (30%), Positives = 92/189 (48%), Gaps = 12/189 (6%) Frame = +3 Query: 57 RKEMADAKQQQAAAPTGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAA--- 227 ++E + K Q AA WKT+ + G SG+LA + P+D IK+++QL + Sbjct: 3 KEEDSLRKGQNVAA----WKTL---LAGAVSGLLARSITAPMDTIKIRLQLTPANGLKPF 55 Query: 228 -----QVAKTMYANEGLGSFYKGLSAGLLRQATYTTARLGSF----RVLTNKAIEANDGR 380 +VA++M NEG+ SF+KG G L TY +A+ S+ R LT +EA R Sbjct: 56 GSQVMEVARSMIKNEGIRSFWKGNIPGSLLYVTYGSAQFSSYSLFNRYLTPFGLEA---R 112 Query: 381 PLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADE 560 LV AF G+T+ + V P D+ R+ A++ + H + + I E Sbjct: 113 LHSLVVGAFAGITS----SIVSYPFDVLRTRLVANNQM------HSMSITREVRDIWKLE 162 Query: 561 GVLALWKGA 587 G+ +KG+ Sbjct: 163 GLPGFFKGS 171 Score = 33.5 bits (75), Expect = 0.58 Identities = 34/172 (19%), Positives = 69/172 (40%), Gaps = 8/172 (4%) Frame = +3 Query: 99 PTGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKI----QLGEGSAAQVAKTMYANEGLG 266 P G+ + V G +G+ ++ V P D+++ ++ Q+ S + + ++ EGL Sbjct: 106 PFGLEARLHSLVVGAFAGITSSIVSYPFDVLRTRLVANNQMHSMSITREVRDIWKLEGLP 165 Query: 267 SFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQK----AFIGLTAGAIG 434 F+KG A + + G++ + I ++ K A + +AG IG Sbjct: 166 GFFKGSIASMTTITLTASIMFGTYETI---RIYCDENEKTTAAHKKWELATLNHSAGTIG 222 Query: 435 ACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAG 590 + L ++ +R + N+ H L + + V +KG G Sbjct: 223 GVIAKIITFPLETIR--------RRMQFMNSKH-LEKFSRHSSVYGSYKGYG 265
>DNC_HUMAN (Q9HC21) Mitochondrial deoxynucleotide carrier (Solute carrier| family 25 member 19) (Mitochondrial uncoupling protein 1) Length = 320 Score = 63.2 bits (152), Expect = 7e-10 Identities = 53/184 (28%), Positives = 80/184 (43%), Gaps = 12/184 (6%) Frame = +3 Query: 129 FVNGGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAK----TMYANEGLGSFYKGLSAG 293 FV GG + +AT + P+D+++ + GE + TMY +EG FYKGL+ Sbjct: 122 FVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPT 181 Query: 294 LLRQATYTTARLG---SFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLA 464 L+ Y + S + L AI A +G+ +Q G AG I + P DL Sbjct: 182 LIAIFPYAGLQFSCYSSLKHLYKWAIPA-EGKKNENLQNLLCGSGAGVISKTLTYPLDLF 240 Query: 465 LIRMQADSTLPA----AQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGML 632 R+Q A Q R YK ++ EG L +KG P++++A M Sbjct: 241 KKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMF 300 Query: 633 ASYD 644 SY+ Sbjct: 301 FSYE 304 Score = 46.2 bits (108), Expect = 9e-05 Identities = 42/175 (24%), Positives = 70/175 (40%), Gaps = 18/175 (10%) Frame = +3 Query: 132 VNGGASGMLATCVIQPIDMIKVKIQL-------GEGSA-----AQVAKTMYANEGLGSFY 275 V G SG++ +I P D+IK++ QL + SA Q ++ + EG +F+ Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79 Query: 276 KGLSAGLLRQATYTTARLGSFRVLTNKAIEAN--DGRPLPLVQKAFIGLTAGAIGACVGS 449 KG + Y + SF +LT + D R + G + AC+ + Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFS------VHFVCGGLAACMAT 133 Query: 450 ----PADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVV 602 P D+ R A + + Y HA+ + EG +KG PT++ Sbjct: 134 LTVHPVDVLRTRFAAQ-----GEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLI 183 Score = 36.2 bits (82), Expect = 0.089 Identities = 28/101 (27%), Positives = 41/101 (40%), Gaps = 5/101 (4%) Frame = +3 Query: 372 DGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTL-----PAAQRRHYKNAFHA 536 DGR Q A G +G + + SP D+ IR Q P+A+ Y A Sbjct: 9 DGRNNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAK---YHGILQA 65 Query: 537 LYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYDQSVEL 659 +I +EG A WKG P + ++ S++ EL Sbjct: 66 SRQILQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTEL 106 Score = 35.8 bits (81), Expect = 0.12 Identities = 23/86 (26%), Positives = 38/86 (44%), Gaps = 14/86 (16%) Frame = +3 Query: 138 GGASGMLATCVIQPIDMIKVKIQLGEGSAAQVA--------------KTMYANEGLGSFY 275 G +G+++ + P+D+ K ++Q+G A+ A K + EG F+ Sbjct: 223 GSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFF 282 Query: 276 KGLSAGLLRQATYTTARLGSFRVLTN 353 KGLS LL+ A T S+ N Sbjct: 283 KGLSPSLLKAALSTGFMFFSYEFFCN 308
>ODC_RAT (Q99JD3) Mitochondrial 2-oxodicarboxylate carrier (Solute carrier| family 25 member 21) Length = 298 Score = 62.4 bits (150), Expect = 1e-09 Identities = 44/166 (26%), Positives = 76/166 (45%), Gaps = 8/166 (4%) Frame = +3 Query: 132 VNGGASGMLATCVIQPIDMIKVKIQLGEG------SAAQVAKTMYANEGLG--SFYKGLS 287 + G SG+ V+ P +++KV +Q+ S A+ + EG G KG + Sbjct: 113 IAGLGSGLTEAVVVNPFEVVKVGLQVNRNMFTEQPSTFAYARQIIKKEGWGFQGLNKGFT 172 Query: 288 AGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 467 A L R + G + + + + D L ++K IG +G +G+ P D+A Sbjct: 173 ATLGRHGIFNMTYFGFYYNVKDNIPSSKDPT-LEFLRKFGIGFVSGTVGSVFNIPFDVAK 231 Query: 468 IRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVR 605 R+Q +P + Y+ F + + +EG+LAL+KG P V+R Sbjct: 232 SRIQGPQPVPGEIK--YRGCFKTMETVYREEGILALYKGLLPKVMR 275 Score = 44.7 bits (104), Expect = 3e-04 Identities = 39/186 (20%), Positives = 75/186 (40%), Gaps = 10/186 (5%) Frame = +3 Query: 114 KTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEG--------SAAQVAKTMYANEGLGS 269 +T + GG +G++ C++ P+D++K + Q+ S + ++ EGL Sbjct: 11 ETCRQVAAGGCAGLVEICLMHPLDVVKTRFQVQRSVTDPQSYKSLRDSFQVIFRTEGLFG 70 Query: 270 FYKGLSAGLLRQATYTTARLGSFRVLTN--KAIEANDGRPLPLVQKAFIGLTAGAIGACV 443 FYKG+ +L + + +F + + + G P+ GL +G A V Sbjct: 71 FYKGIIPPILAETPKRAVKFSTFELYKKFLGYMSLSPGLTFPIA-----GLGSGLTEAVV 125 Query: 444 GSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNM 623 +P ++ + +Q + + Q + A + + G L KG T+ R NM Sbjct: 126 VNPFEVVKVGLQVNRNMFTEQPSTFAYARQIIKK--EGWGFQGLNKGFTATLGRHGIFNM 183 Query: 624 GMLASY 641 Y Sbjct: 184 TYFGFY 189
>DNC_PONPY (Q5NVC1) Mitochondrial deoxynucleotide carrier (Solute carrier| family 25 member 19) Length = 320 Score = 62.0 bits (149), Expect = 2e-09 Identities = 52/180 (28%), Positives = 81/180 (45%), Gaps = 12/180 (6%) Frame = +3 Query: 129 FVNGGASGMLATCVIQPIDMIKVKIQL-GE----GSAAQVAKTMYANEGLGSFYKGLSAG 293 FV GG + +AT + P+D+++ + GE + TMY +EG FYKGL+ Sbjct: 122 FVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLCHAVGTMYRSEGPQVFYKGLAPT 181 Query: 294 LLRQATYTTARLG---SFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLA 464 L+ Y + S + L AI A +G+ +Q G AG I + P DL Sbjct: 182 LIAIFPYAGLQFSCYSSLKHLYKWAIPA-EGKKNENLQNLLCGSGAGVISKTLTYPLDLF 240 Query: 465 LIRMQADSTLPA----AQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGML 632 R+Q A Q R YK ++ EG L +KG P++++A +L+ G + Sbjct: 241 KKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKA-ALSTGFM 299 Score = 46.2 bits (108), Expect = 9e-05 Identities = 40/175 (22%), Positives = 68/175 (38%), Gaps = 18/175 (10%) Frame = +3 Query: 132 VNGGASGMLATCVIQPIDMIKVKIQLGEGSAA------------QVAKTMYANEGLGSFY 275 V G SG++ +I P D+IK++ QL + Q ++ + EG +F+ Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPNAKYHGILQASRQILQEEGPTAFW 79 Query: 276 KGLSAGLLRQATYTTARLGSFRVLTNKAIEAN--DGRPLPLVQKAFIGLTAGAIGACVGS 449 KG + Y + SF +LT + D R + G + AC+ + Sbjct: 80 KGHIPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFS------VHFVCGGLAACMAT 133 Query: 450 ----PADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVV 602 P D+ R A + + Y HA+ + EG +KG PT++ Sbjct: 134 LTVHPVDVLRTRFAAQ-----GEPKVYNTLCHAVGTMYRSEGPQVFYKGLAPTLI 183 Score = 36.2 bits (82), Expect = 0.089 Identities = 26/98 (26%), Positives = 40/98 (40%), Gaps = 2/98 (2%) Frame = +3 Query: 372 DGRPLPLVQKAFIGLTAGAIGACVGSPADLALIR--MQADSTLPAAQRRHYKNAFHALYR 545 DGR Q A G +G + + SP D+ IR +Q + + Y A + Sbjct: 9 DGRNNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPNAKYHGILQASRQ 68 Query: 546 ITADEGVLALWKGAGPTVVRAMSLNMGMLASYDQSVEL 659 I +EG A WKG P + ++ S++ EL Sbjct: 69 ILQEEGPTAFWKGHIPAQILSIGYGAVQFLSFEMLTEL 106
>COLT_DROME (Q9VQG4) Congested-like trachea protein| Length = 306 Score = 60.8 bits (146), Expect = 3e-09 Identities = 46/173 (26%), Positives = 77/173 (44%), Gaps = 9/173 (5%) Frame = +3 Query: 129 FVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQ--------VAKTMYANEGLGSFYKGL 284 FV G SG+ +T ++ P + IKV +Q +G + A +Y GL S +KG Sbjct: 119 FVAGSFSGLFSTLIMAPGERIKVLLQTQQGQGGERKYNGMIDCAGKLYKEGGLRSVFKGS 178 Query: 285 SAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLA 464 A +LR + L + A ++ + F G AG +G PAD+ Sbjct: 179 CATMLRDLPANGLYFLVYEALQDVAKSKSETGQISTASTIFAGGVAGMAYWILGMPADVL 238 Query: 465 LIRMQADSTLPAAQRRHYKNAFHALYR-ITADEGVLALWKGAGPTVVRAMSLN 620 R+Q +A YK+ ++++ + +G LAL++G P ++RA N Sbjct: 239 KSRLQ------SAPEGTYKHGIRSVFKDLIVKDGPLALYRGVTPIMLRAFPAN 285 Score = 44.7 bits (104), Expect = 3e-04 Identities = 41/178 (23%), Positives = 72/178 (40%), Gaps = 11/178 (6%) Frame = +3 Query: 120 IKPFVNGGASGMLATCVIQPIDMIKVKIQ-----------LGEGSAAQVAKTMYANEGLG 266 +K F+ GG G+ P+D IKV++Q L G+ AKT+ NEG+ Sbjct: 16 VKSFLTGGFGGICNVLSGHPLDTIKVRLQTMPRPAPGEQPLYRGTFDCAAKTI-KNEGVR 74 Query: 267 SFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVG 446 YKG+SA L A + L + + + L Q G +G + Sbjct: 75 GLYKGMSAPLTGVAPIFAMCFAGY-ALGKRLQQRGEDAKLTYPQIFVAGSFSGLFSTLIM 133 Query: 447 SPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLN 620 +P + + +Q R Y ++ + G+ +++KG+ T++R + N Sbjct: 134 APGERIKVLLQTQQ--GQGGERKYNGMIDCAGKLYKEGGLRSVFKGSCATMLRDLPAN 189
>ARG13_NEUCR (Q01356) Amino acid transporter arg-13| Length = 363 Score = 60.1 bits (144), Expect = 6e-09 Identities = 59/206 (28%), Positives = 90/206 (43%), Gaps = 37/206 (17%) Frame = +3 Query: 138 GGASGMLATCVIQPIDMIKVKIQLGE---GSAAQ--------VAKTMYANEGLGSFYKGL 284 GG SG + ++ P++++K KIQ+ + G+ A+ V K ++ +EGL F+ G Sbjct: 150 GGFSGAFTSLILTPVELVKCKIQVPDEPGGAGARQRQLKPIPVIKEIFRHEGLRGFWHGQ 209 Query: 285 SAGLLRQATYTTARLGS-------FRVLTNKA----------IEANDGRPLPLVQKAFIG 413 L+R+A A GS FR +A + A+ RPLPL Q+A G Sbjct: 210 LGTLIREAGGCAAWFGSKETTSKWFRGRNERALLKRGASQEEVVASRERPLPLWQQAIAG 269 Query: 414 LTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK---- 581 +AG + PAD RMQ S + K A + + + E ALWK Sbjct: 270 ASAGMSYNFLFFPADTVKSRMQT-SPIGGGGDNGGKGAATMMPKKSFGEEARALWKQAGI 328 Query: 582 -----GAGPTVVRAMSLNMGMLASYD 644 G G TV+R+ + + YD Sbjct: 329 KGFYRGCGITVLRSAPSSAFIFMVYD 354 Score = 42.0 bits (97), Expect = 0.002 Identities = 43/181 (23%), Positives = 74/181 (40%), Gaps = 13/181 (7%) Frame = +3 Query: 102 TGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQ-------LGEGSAAQVAKTMYANEG 260 T V + ++ V G A+G++ + P D +KV++Q L + +G Sbjct: 37 TAVMEALEDIVYGSAAGIVGKYIEYPFDTVKVRLQSQPDHLPLRYTGPLDCFRQSIRADG 96 Query: 261 LGSFYKGLSAGLLRQATYTTA-----RLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAG 425 Y+G+SA L+ A ++ R+G R L + A L L F G +G Sbjct: 97 FLGLYRGISAPLVGAALENSSLFFFERIG--RSLLYSSGFAPRDSELSLSALWFTGGFSG 154 Query: 426 AIGACVGSPADLALIRMQA-DSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVV 602 A + + +P +L ++Q D A R+ + I EG+ W G T++ Sbjct: 155 AFTSLILTPVELVKCKIQVPDEPGGAGARQRQLKPIPVIKEIFRHEGLRGFWHGQLGTLI 214 Query: 603 R 605 R Sbjct: 215 R 215
>DNC_MACFA (Q5IS35) Mitochondrial deoxynucleotide carrier (Solute carrier| family 25 member 19) Length = 320 Score = 60.1 bits (144), Expect = 6e-09 Identities = 49/179 (27%), Positives = 78/179 (43%), Gaps = 11/179 (6%) Frame = +3 Query: 129 FVNGGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAK----TMYANEGLGSFYKGLSAG 293 FV GG + AT + P+D+++ + GE + TMY +EG FYKGL+ Sbjct: 122 FVCGGLAACTATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPT 181 Query: 294 LLRQATYTTARLGSFRVLTN--KAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 467 L+ Y + + L + K +G+ +Q G AG I + P DL Sbjct: 182 LIAIFPYAGLQFSCYSSLKHLYKWAMPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFK 241 Query: 468 IRMQADSTLPA----AQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGML 632 R+Q A Q R YK ++ EG L +KG P++++A +L+ G + Sbjct: 242 KRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKA-ALSTGFM 299 Score = 48.1 bits (113), Expect = 2e-05 Identities = 41/175 (23%), Positives = 68/175 (38%), Gaps = 18/175 (10%) Frame = +3 Query: 132 VNGGASGMLATCVIQPIDMIKVKIQLGEGSAA------------QVAKTMYANEGLGSFY 275 V G SG++ +I P D+IK++ QL + Q ++ + EGL +F+ Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRRDPNAKYHGIFQASRQILQEEGLTAFW 79 Query: 276 KGLSAGLLRQATYTTARLGSFRVLTNKAIEAN--DGRPLPLVQKAFIGLTAGAIGACVGS 449 KG + Y + SF +LT + D R + G + AC + Sbjct: 80 KGHIPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFS------VHFVCGGLAACTAT 133 Query: 450 ----PADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVV 602 P D+ R A + + Y HA+ + EG +KG PT++ Sbjct: 134 LTVHPVDVLRTRFAAQ-----GEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLI 183 Score = 40.0 bits (92), Expect = 0.006 Identities = 27/98 (27%), Positives = 42/98 (42%), Gaps = 2/98 (2%) Frame = +3 Query: 372 DGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQ--RRHYKNAFHALYR 545 DGR +Q A G +G + + SP D+ IR Q + + Y F A + Sbjct: 9 DGRNNTKLQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRRDPNAKYHGIFQASRQ 68 Query: 546 ITADEGVLALWKGAGPTVVRAMSLNMGMLASYDQSVEL 659 I +EG+ A WKG P + ++ S++ EL Sbjct: 69 ILQEEGLTAFWKGHIPAQILSIGYGAVQFLSFEMLTEL 106
>YD1K_SCHPO (Q10248) Putative mitochondrial carrier C4G9.20c| Length = 302 Score = 59.7 bits (143), Expect = 8e-09 Identities = 49/183 (26%), Positives = 79/183 (43%), Gaps = 7/183 (3%) Frame = +3 Query: 108 VWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGE------GSAAQVAKTMYANEGLGS 269 V+ K F+ G + G+ V QP D +KV++Q +A K + NEGL + Sbjct: 14 VFSFTKDFLAGVSGGVAQVLVGQPFDCVKVRLQSQSNVSPIYNNALDCVKKISKNEGLAA 73 Query: 270 FYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGS 449 FYKG LL + + +F K + DG P+ + Q G +G + + Sbjct: 74 FYKGTVLPLLGIGFCVSIQFTTFEYC--KRFFSRDGTPVTMPQYYVSGAISGLANSFLVG 131 Query: 450 PADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVR-AMSLNMG 626 P + IR+Q + + Y + + +I++ G+ + KG PT R A L M Sbjct: 132 PVEHVRIRLQ----IQTGKNVLYHGPWDCIKKISSQYGLSGIMKGYNPTAAREAHGLGMY 187 Query: 627 MLA 635 LA Sbjct: 188 FLA 190 Score = 43.9 bits (102), Expect = 4e-04 Identities = 37/173 (21%), Positives = 69/173 (39%), Gaps = 9/173 (5%) Frame = +3 Query: 129 FVNGGASGMLATCVIQPIDMIKVKIQLGEGSAA------QVAKTMYANEGLGSFYKGLSA 290 +V+G SG+ + ++ P++ +++++Q+ G K + + GL KG + Sbjct: 116 YVSGAISGLANSFLVGPVEHVRIRLQIQTGKNVLYHGPWDCIKKISSQYGLSGIMKGYNP 175 Query: 291 GLLRQATYTTARLGSFRVLTNKAIEAN---DGRPLPLVQKAFIGLTAGAIGACVGSPADL 461 R+A ++ L + + D P + G AG P D+ Sbjct: 176 TAAREAHGLGMYFLAYEALVKNTMAKHHLTDRSQTPGWKLCVFGAGAGYAMWLAAYPFDI 235 Query: 462 ALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLN 620 ++Q D L A YKN++ I G+ ++G P +VRA N Sbjct: 236 VKSKIQTDGFLSKAT---YKNSWQCAKGIYTKAGLRGFYRGFVPVLVRAAPAN 285
>ODC2_YEAST (Q99297) Mitochondrial 2-oxodicarboxylate carrier 2| Length = 307 Score = 59.3 bits (142), Expect = 1e-08 Identities = 49/164 (29%), Positives = 77/164 (46%), Gaps = 8/164 (4%) Frame = +3 Query: 138 GGASGMLATCVIQPIDMIKVKIQLGEGS---AAQVAKTMYANEGLGSFYKGLSAGLLRQA 308 G ++GM VI P ++IK+++Q + S K NEG+ YKG+ + + R A Sbjct: 125 GASAGMTEAAVIVPFELIKIRMQDVKSSYLGPMDCLKKTIKNEGIMGLYKGIESTMWRNA 184 Query: 309 TYTTARLG-SFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVG----SPADLALIR 473 + G ++V + + G QK L AGAIG VG +P D+ R Sbjct: 185 LWNGGYFGVIYQVRNSMPVAKTKG------QKTRNDLIAGAIGGTVGTMLNTPFDVVKSR 238 Query: 474 MQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVR 605 +Q+ + +A ++ Y +L I +EG AL+KG P V R Sbjct: 239 IQSVDAVSSAVKK-YNWCLPSLLVIYREEGFRALYKGFVPKVCR 281 Score = 47.4 bits (111), Expect = 4e-05 Identities = 45/189 (23%), Positives = 75/189 (39%), Gaps = 20/189 (10%) Frame = +3 Query: 120 IKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVA---------------KTMYAN 254 I F++G +G+ V+ P+D++K + QL + A K + Sbjct: 13 IYQFISGAVAGISELTVMYPLDVVKTRFQLEVTTPTAAAVGKQVERYNGVIDCLKKIVKK 72 Query: 255 EGLGSFYKGLSAGLLRQATYTTARLG---SFRVLTNKAIEANDGRPLPLVQKAFI--GLT 419 EG Y+G+S+ +L +A + ++ + N+ QK I G + Sbjct: 73 EGFSRLYRGISSPMLMEAPKRATKFACNDQYQKIFKNLFNTNE-----TTQKISIAAGAS 127 Query: 420 AGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTV 599 AG A V P +L IRMQ + Y L + +EG++ L+KG T+ Sbjct: 128 AGMTEAAVIVPFELIKIRMQD-------VKSSYLGPMDCLKKTIKNEGIMGLYKGIESTM 180 Query: 600 VRAMSLNMG 626 R N G Sbjct: 181 WRNALWNGG 189 Score = 36.2 bits (82), Expect = 0.089 Identities = 24/86 (27%), Positives = 37/86 (43%), Gaps = 6/86 (6%) Frame = +3 Query: 369 NDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAA-----QRRHYKNAFH 533 ++ +PLP + + G AG V P D+ R Q + T P A Q Y Sbjct: 5 SNAKPLPFIYQFISGAVAGISELTVMYPLDVVKTRFQLEVTTPTAAAVGKQVERYNGVID 64 Query: 534 ALYRITADEGVLALWKG-AGPTVVRA 608 L +I EG L++G + P ++ A Sbjct: 65 CLKKIVKKEGFSRLYRGISSPMLMEA 90
>DNC_MOUSE (Q9DAM5) Mitochondrial deoxynucleotide carrier (Solute carrier| family 25 member 19) Length = 318 Score = 58.5 bits (140), Expect = 2e-08 Identities = 46/179 (25%), Positives = 79/179 (44%), Gaps = 11/179 (6%) Frame = +3 Query: 129 FVNGGASGMLATCVIQPIDMIKVKIQL-GE----GSAAQVAKTMYANEGLGSFYKGLSAG 293 FV GG S AT + P+D+++ ++ GE + + +TMY EG FYKGL+ Sbjct: 122 FVCGGLSAGTATLTVHPVDVLRTRLAAQGEPKIYNNLREAIRTMYKTEGPFVFYKGLTPT 181 Query: 294 LLRQATYTTARLGSFRVLTNKA--IEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 467 ++ Y + +R L + DG+ ++ G +G I P DL Sbjct: 182 VIAIFPYAGLQFSCYRSLKRAYDWLIPPDGKQTGNLKNLLCGCGSGVISKTFTYPLDLIK 241 Query: 468 IRMQADSTLPA----AQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGML 632 R+Q A Q R Y+ ++ +EG +KG P++++A +L+ G + Sbjct: 242 KRLQVGGFEHARSAFGQVRSYRGLLDLTQQVLQEEGTRGFFKGLSPSLMKA-ALSTGFM 299 Score = 47.0 bits (110), Expect = 5e-05 Identities = 41/169 (24%), Positives = 66/169 (39%), Gaps = 12/169 (7%) Frame = +3 Query: 132 VNGGASGMLATCVIQPIDMIKVKIQL-------GEGSAA-----QVAKTMYANEGLGSFY 275 V G SG + +I P+D+IK++ QL + +A Q AK + EG +F+ Sbjct: 20 VAGSVSGFVTRALISPLDVIKIRFQLQIERLCPSDPNAKYHGIFQAAKQILQEEGPRAFW 79 Query: 276 KGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPA 455 KG + Y + +F LT +AN + G + P Sbjct: 80 KGHVPAQILSIGYGAVQFLAFEELTELLYQANLYQTHQFSAHFVCGGLSAGTATLTVHPV 139 Query: 456 DLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVV 602 D+ R+ A + + Y N A+ + EG +KG PTV+ Sbjct: 140 DVLRTRLAAQ-----GEPKIYNNLREAIRTMYKTEGPFVFYKGLTPTVI 183 Score = 39.3 bits (90), Expect = 0.011 Identities = 25/98 (25%), Positives = 43/98 (43%), Gaps = 2/98 (2%) Frame = +3 Query: 372 DGRPLPLVQKAFIGLTAGAIGACVGSPADLALIR--MQADSTLPAAQRRHYKNAFHALYR 545 D R ++ A G +G + + SP D+ IR +Q + P+ Y F A + Sbjct: 9 DVRSNSKLEVAVAGSVSGFVTRALISPLDVIKIRFQLQIERLCPSDPNAKYHGIFQAAKQ 68 Query: 546 ITADEGVLALWKGAGPTVVRAMSLNMGMLASYDQSVEL 659 I +EG A WKG P + ++ ++++ EL Sbjct: 69 ILQEEGPRAFWKGHVPAQILSIGYGAVQFLAFEELTEL 106 Score = 34.3 bits (77), Expect = 0.34 Identities = 22/80 (27%), Positives = 38/80 (47%), Gaps = 14/80 (17%) Frame = +3 Query: 120 IKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVA--------------KTMYANE 257 +K + G SG+++ P+D+IK ++Q+G A+ A + + E Sbjct: 217 LKNLLCGCGSGVISKTFTYPLDLIKKRLQVGGFEHARSAFGQVRSYRGLLDLTQQVLQEE 276 Query: 258 GLGSFYKGLSAGLLRQATYT 317 G F+KGLS L++ A T Sbjct: 277 GTRGFFKGLSPSLMKAALST 296
>MCATL_HUMAN (Q8N8R3) Mitchondrial carnitine/acylcarnitine carrier protein CACL| (CACT-like) (Solute carrier family 25 member 29) Length = 303 Score = 58.5 bits (140), Expect = 2e-08 Identities = 45/180 (25%), Positives = 80/180 (44%), Gaps = 7/180 (3%) Frame = +3 Query: 120 IKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAK-------TMYANEGLGSFYK 278 + F+ G A+G + + P+++ K ++QL + A+ K +Y +EGL + Sbjct: 93 LNQFLAGAAAGAIQCVICCPMELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNR 152 Query: 279 GLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPAD 458 G+ + LLR+ ++ LT +A+ G L + + G T+G + P D Sbjct: 153 GMVSTLLRETPSFGVYFLTYDALT-RALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVD 211 Query: 459 LALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLAS 638 + R+QAD A + R + H YR EG +G T++RA +N A+ Sbjct: 212 VVKSRLQADGLRGAPRYRGILDCVHQSYRA---EGWRVFTRGLASTLLRAFPVNAATFAT 268 Score = 52.8 bits (125), Expect = 9e-07 Identities = 48/165 (29%), Positives = 74/165 (44%), Gaps = 6/165 (3%) Frame = +3 Query: 129 FVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTMYA------NEGLGSFYKGLSA 290 F+ G A G+ V P D +KV++Q+ Q T++ E + YKGL + Sbjct: 5 FLAGCAGGVAGVLVGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLYKGLGS 64 Query: 291 GLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALI 470 L+ T+ A + + T +A+ G PL Q G AGAI + P +LA Sbjct: 65 PLM-GLTFINALVFGVQGNTLRAL----GHDSPLNQ-FLAGAAAGAIQCVICCPMELAKT 118 Query: 471 RMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVR 605 R+Q PA R YK + L +I EG+ + +G T++R Sbjct: 119 RLQLQDAGPA---RTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLR 160 Score = 29.6 bits (65), Expect = 8.3 Identities = 22/86 (25%), Positives = 36/86 (41%), Gaps = 7/86 (8%) Frame = +3 Query: 123 KPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAA-------QVAKTMYANEGLGSFYKG 281 K + GG SG+++ P+D++K ++Q A Y EG F +G Sbjct: 191 KLLLAGGTSGIVSWLSTYPVDVVKSRLQADGLRGAPRYRGILDCVHQSYRAEGWRVFTRG 250 Query: 282 LSAGLLRQATYTTARLGSFRVLTNKA 359 L++ LLR A + V+ A Sbjct: 251 LASTLLRAFPVNAATFATVTVVLTYA 276
>YMC2_YEAST (P38087) Carrier protein YMC2, mitochondrial precursor| Length = 329 Score = 57.8 bits (138), Expect = 3e-08 Identities = 44/182 (24%), Positives = 79/182 (43%), Gaps = 17/182 (9%) Frame = +3 Query: 114 KTIKPFVNGGASGMLATCVIQPIDMIKVKIQLG--EGSAAQVAKTMYANEGLGSFYKGLS 287 + +K G G+ V QP D KV++Q + +V + + NEG+ +FYKG Sbjct: 33 RVLKDIFAGTIGGIAQVLVGQPFDTTKVRLQTATTRTTTLEVLRNLVKNEGVFAFYKGAL 92 Query: 288 AGLLRQATYTTARLGSFRVL---------------TNKAIEANDGRPLPLVQKAFIGLTA 422 LL + + G + +++ ++ + LPL Q GLT Sbjct: 93 TPLLGVGICVSVQFGVNEAMKRFFQNYNASKNPNMSSQDVDLSRSNTLPLSQYYVCGLTG 152 Query: 423 GAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVV 602 G + + + SP + IR+Q ++ R +K + + ++ A G L +G PT++ Sbjct: 153 GVVNSFLASPIEQIRIRLQTQTS--NGGDREFKGPWDCIKKLKAQGG---LMRGLFPTMI 207 Query: 603 RA 608 RA Sbjct: 208 RA 209 Score = 42.7 bits (99), Expect = 0.001 Identities = 24/77 (31%), Positives = 40/77 (51%), Gaps = 7/77 (9%) Frame = +3 Query: 138 GGASGMLATCVIQPIDMIKVKIQLGE-------GSAAQVAKTMYANEGLGSFYKGLSAGL 296 G SG + + P+D++K IQ + S + VAKT+YA EG+ +F+KG + Sbjct: 246 GAFSGTMLWLTVYPLDVVKSIIQNDDLRKPKYKNSISYVAKTIYAKEGIRAFFKGFGPTM 305 Query: 297 LRQATYTTARLGSFRVL 347 +R A A +F ++ Sbjct: 306 VRSAPVNGATFLTFELV 322 Score = 36.6 bits (83), Expect = 0.068 Identities = 43/184 (23%), Positives = 79/184 (42%), Gaps = 12/184 (6%) Frame = +3 Query: 129 FVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTMYANEGLGSFYKGLSA--GLLR 302 +V G G++ + + PI+ I++++Q + +G K L A GL+R Sbjct: 146 YVCGLTGGVVNSFLASPIEQIRIRLQTQTSNGGD-----REFKGPWDCIKKLKAQGGLMR 200 Query: 303 QATYTTAR----LGSFRVLTNKAIEANDGRPL-----PLVQKAFIGLTAGAIGACVGSPA 455 T R LG++ ++ + G L P + G +G + P Sbjct: 201 GLFPTMIRAGHGLGTYFLVYEALVAREIGTGLTRNEIPPWKLCLFGAFSGTMLWLTVYPL 260 Query: 456 DLALIRMQADSTLPAAQRRHYKNAFHALYR-ITADEGVLALWKGAGPTVVRAMSLNMGML 632 D+ +Q D ++ YKN+ + + I A EG+ A +KG GPT+VR+ +N Sbjct: 261 DVVKSIIQNDDL----RKPKYKNSISYVAKTIYAKEGIRAFFKGFGPTMVRSAPVNGATF 316 Query: 633 ASYD 644 +++ Sbjct: 317 LTFE 320
>TXTP_CAEEL (P34519) Putative tricarboxylate transport protein, mitochondrial| precursor (Citrate transport protein) (CTP) Length = 312 Score = 57.8 bits (138), Expect = 3e-08 Identities = 50/195 (25%), Positives = 82/195 (42%), Gaps = 15/195 (7%) Frame = +3 Query: 66 MADAKQQQAAAPTGVW-------KTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSA 224 M+ + A P +W KT++ V GG +G + C+ P + +K ++QL E SA Sbjct: 1 MSGIQPVPGAKPLSMWQQYGPSEKTVRGIVIGGITGGIEICITFPTEYVKTQLQLDERSA 60 Query: 225 A-------QVAKTMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRP 383 K G Y+GLS L ++ R G+F L ++A A++ Sbjct: 61 TPKFRGPIDCVKQTVNGHGFFGLYRGLSVLLYGSIPKSSFRFGTFEYLKSQA--ADERGN 118 Query: 384 LPLVQKAFIGLTAGAIGACVG-SPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADE 560 L V + GL AG A +P + ++ D L + YK H + I E Sbjct: 119 LSPVMRLLCGLGAGLSEAVFAVTPMETVKVKFIHDQGLAQPK---YKGFVHGVGCIVKAE 175 Query: 561 GVLALWKGAGPTVVR 605 G+ ++KG T+ + Sbjct: 176 GLGGIYKGVTATMAK 190 Score = 57.4 bits (137), Expect = 4e-08 Identities = 54/214 (25%), Positives = 89/214 (41%), Gaps = 9/214 (4%) Frame = +3 Query: 42 PARSRRKEMADAKQQQAAAPTGVWKTIKPFVNGGASGML-ATCVIQPIDMIKVKIQLGEG 218 P S R + + QAA G + + G +G+ A + P++ +KVK +G Sbjct: 96 PKSSFRFGTFEYLKSQAADERGNLSPVMRLLCGLGAGLSEAVFAVTPMETVKVKFIHDQG 155 Query: 219 SAAQVAK-------TMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDG 377 A K + EGLG YKG++A + +Q + R L + ++ Sbjct: 156 LAQPKYKGFVHGVGCIVKAEGLGGIYKGVTATMAKQGSNQAIRFFVMETLKDWYRGGDNT 215 Query: 378 RPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITAD 557 +P+ +G AGA +P D+ RMQ + + YKN +I Sbjct: 216 QPISKPIVGLMGAVAGAASVYGNTPIDVVKTRMQ------GLEAKKYKNTLDCAMQIWKK 269 Query: 558 EGVLALWKGAGPTVVRAMSLNMGM-LASYDQSVE 656 EG A +KG P + R + L++G+ YD +E Sbjct: 270 EGFFAFYKGTVPRLSR-VCLDVGITFMIYDSIIE 302
>CMC1_DROME (Q9VA73) Calcium-binding mitochondrial carrier Aralar1| Length = 695 Score = 57.4 bits (137), Expect = 4e-08 Identities = 50/193 (25%), Positives = 86/193 (44%), Gaps = 3/193 (1%) Frame = +3 Query: 39 SPARSRRKEMADAKQQQAAAPTGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQL-GE 215 +P ++ + + D + + G T + GG +G P++++K+++Q+ GE Sbjct: 415 APEKAIKLTVNDLVRDKLTDKKGNIPTWAEVLAGGCAGASQVVFTNPLEIVKIRLQVAGE 474 Query: 216 -GSAAQVAKTMYANE-GLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLP 389 S +++ E GL YKG A LLR ++ ++ T + DG P Sbjct: 475 IASGSKIRAWSVVRELGLFGLYKGARACLLRDVPFSAIYFPTY-AHTKAMMADKDGYNHP 533 Query: 390 LVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVL 569 L A G AG A + +PAD+ R+Q + + + Y + A +I A+EG Sbjct: 534 LTLLA-AGAIAGVPAASLVTPADVIKTRLQV---VARSGQTTYTGVWDATKKIMAEEGPR 589 Query: 570 ALWKGAGPTVVRA 608 A WKG V R+ Sbjct: 590 AFWKGTAARVFRS 602 Score = 38.5 bits (88), Expect = 0.018 Identities = 25/97 (25%), Positives = 44/97 (45%) Frame = +3 Query: 312 YTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADST 491 + T RL + + + A + + L + +G AGA+GA V P DL RMQ Sbjct: 316 HMTHRLAEIKAVESPADRSAFIQVLESSYRFTLGSFAGAVGATVVYPIDLVKTRMQNQRA 375 Query: 492 LPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVV 602 Y+N++ ++ EG + L++G P ++ Sbjct: 376 GSYIGEVAYRNSWDCFKKVVRHEGFMGLYRGLLPQLM 412
>DIF1_CAEEL (Q27257) Protein dif-1| Length = 312 Score = 56.2 bits (134), Expect = 8e-08 Identities = 44/183 (24%), Positives = 74/183 (40%), Gaps = 11/183 (6%) Frame = +3 Query: 129 FVNGGASGMLATCVIQPIDMIKVKIQL------GEG----SAAQVAKTMYANEGLGSFYK 278 F+ GG G V P D +KV+IQ GE A K + EG + YK Sbjct: 8 FIAGGVGGSCTVIVGHPFDTVKVRIQTMPMPKPGEKPQFTGALDCVKRTVSKEGFFALYK 67 Query: 279 GLSAGLLRQATYTTARLGSFRVLTNKAIEAND-GRPLPLVQKAFIGLTAGAIGACVGSPA 455 G++A L+ + G V K ++ D + + +Q A G AG V P Sbjct: 68 GMAAPLVGVSPLFAVFFGGCAV--GKWLQQTDPSQEMTFIQNANAGALAGVFTTIVMVPG 125 Query: 456 DLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLA 635 + +Q A HY + ++ G+ ++++G G T++R + + L+ Sbjct: 126 ERIKCLLQVQQAGSAGSGVHYDGPLDVVKKLYKQGGISSIYRGTGATLLRDIPASAAYLS 185 Query: 636 SYD 644 Y+ Sbjct: 186 VYE 188 Score = 55.5 bits (132), Expect = 1e-07 Identities = 47/171 (27%), Positives = 70/171 (40%), Gaps = 10/171 (5%) Frame = +3 Query: 138 GGASGMLATCVIQPIDMIKVKIQLGEGSAA----------QVAKTMYANEGLGSFYKGLS 287 G +G+ T V+ P + IK +Q+ + +A V K +Y G+ S Y+G Sbjct: 111 GALAGVFTTIVMVPGERIKCLLQVQQAGSAGSGVHYDGPLDVVKKLYKQGGISSIYRGTG 170 Query: 288 AGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 467 A LLR + A L + L K R L G AG V PAD+ Sbjct: 171 ATLLRDIPASAAYLSVYEYLKKKFSGEGAQRTLSPGATLMAGGLAGIANWGVCIPADVLK 230 Query: 468 IRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLN 620 R+Q A + ++ L + +EG AL+KG P ++RA N Sbjct: 231 SRLQT-----APEGKYPDGIRGVLREVLREEGPRALFKGFWPVMLRAFPAN 276
>AGC1_YEAST (Q12482) Mitochondrial aspartate-glutamate transporter AGC1| (Aspartate-glutamate carrier 1) Length = 902 Score = 55.8 bits (133), Expect = 1e-07 Identities = 48/214 (22%), Positives = 92/214 (42%), Gaps = 12/214 (5%) Frame = +3 Query: 39 SPARSRRKEMADAKQQQAAAPTGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQL--- 209 +P ++ + + D + + G ++G ++G P++++K+++Q+ Sbjct: 598 APEKAIKLTVNDFMRNRLTDKNGKLSLFPEIISGASAGACQVIFTNPLEIVKIRLQVQSD 657 Query: 210 --GEG--SAAQVAKTMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDG 377 GE A + A + GL Y G++A L+R ++ ++ L + + Sbjct: 658 YVGENIQQANETATQIVKKLGLRGLYNGVAACLMRDVPFSAIYFPTYAHLKKDLFDFDPN 717 Query: 378 RPLPLVQ-KAFIGLTAGAIG----ACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALY 542 + K + LTAGAI A + +P D+ R+Q D P Y FHA+ Sbjct: 718 DKTKRNRLKTWELLTAGAIAGMPAAFLTTPFDVIKTRLQID---PRKGETKYNGIFHAIR 774 Query: 543 RITADEGVLALWKGAGPTVVRAMSLNMGMLASYD 644 I +E + +KG G V+R+ LA+Y+ Sbjct: 775 TILKEESFRSFFKGGGARVLRSSPQFGFTLAAYE 808 Score = 45.1 bits (105), Expect = 2e-04 Identities = 25/65 (38%), Positives = 34/65 (52%) Frame = +3 Query: 408 IGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGA 587 +G AG IGA V P D RMQA +L YKN+ L +I + EG+ L+ G Sbjct: 536 LGSIAGCIGATVVYPIDFIKTRMQAQRSLA-----QYKNSIDCLLKIISREGIKGLYSGL 590 Query: 588 GPTVV 602 GP ++ Sbjct: 591 GPQLI 595
>AGC1_ASHGO (Q75AH6) Mitochondrial aspartate-glutamate transporter AGC1| (Aspartate-glutamate carrier 1) Length = 911 Score = 55.5 bits (132), Expect = 1e-07 Identities = 43/171 (25%), Positives = 76/171 (44%), Gaps = 5/171 (2%) Frame = +3 Query: 108 VWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEG-----SAAQVAKTMYANEGLGSF 272 ++ +I F G +G + V+ PIDM+K ++Q ++ + + EG+ Sbjct: 520 IFDSIYNFTLGSVAGCIGAMVVYPIDMVKTRMQAQRDFSKYKNSIDCLLKILSKEGVRGL 579 Query: 273 YKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSP 452 Y GL L+ A +L + + DG+ L L + G TAGA +P Sbjct: 580 YSGLGPQLIGVAPEKAIKL-TVNDHMRATLAGRDGK-LSLPCEIISGATAGACQVVFTNP 637 Query: 453 ADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVR 605 ++ IR+Q S A R+ NA + + G++ L++GAG ++R Sbjct: 638 LEIVKIRLQVKSDYVADAARNSVNAISVIKNL----GLIGLYRGAGACLLR 684 Score = 48.9 bits (115), Expect = 1e-05 Identities = 44/213 (20%), Positives = 87/213 (40%), Gaps = 11/213 (5%) Frame = +3 Query: 39 SPARSRRKEMADAKQQQAAAPTGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEG 218 +P ++ + + D + A G ++G +G P++++K+++Q+ Sbjct: 591 APEKAIKLTVNDHMRATLAGRDGKLSLPCEIISGATAGACQVVFTNPLEIVKIRLQVKSD 650 Query: 219 SAAQVAK------TMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAI-----E 365 A A+ ++ N GL Y+G A LLR ++ ++ + + + Sbjct: 651 YVADAARNSVNAISVIKNLGLIGLYRGAGACLLRDIPFSAIYFPTYAHIKSNVFNFDPKD 710 Query: 366 ANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYR 545 ++ L Q G AG A + +P D+ R+Q D P Y + A Sbjct: 711 SDKRNKLNTWQLLVSGGLAGMPAAFLTTPFDVIKTRLQID---PKKGESVYNGIWDAART 767 Query: 546 ITADEGVLALWKGAGPTVVRAMSLNMGMLASYD 644 I +EG+ + +KG V+R+ LA+Y+ Sbjct: 768 ILKEEGIKSFFKGGPARVLRSSPQFGFTLAAYE 800 Score = 44.3 bits (103), Expect = 3e-04 Identities = 28/101 (27%), Positives = 46/101 (45%), Gaps = 7/101 (6%) Frame = +3 Query: 72 DAKQQQAAAPTGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQV------ 233 D K W+ + V+GG +GM A + P D+IK ++Q+ V Sbjct: 707 DPKDSDKRNKLNTWQLL---VSGGLAGMPAAFLTTPFDVIKTRLQIDPKKGESVYNGIWD 763 Query: 234 -AKTMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTN 353 A+T+ EG+ SF+KG A +LR + L ++ + N Sbjct: 764 AARTILKEEGIKSFFKGGPARVLRSSPQFGFTLAAYEIFHN 804
>MCAT_ARATH (Q93XM7) Mitochondrial carnitine/acylcarnitine carrier-like protein| (Protein A BOUT DE SOUFFLE) (Carnitine/acylcarnitine translocase-like protein) (CAC-like protein) Length = 300 Score = 55.1 bits (131), Expect = 2e-07 Identities = 53/196 (27%), Positives = 80/196 (40%), Gaps = 18/196 (9%) Frame = +3 Query: 111 WKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEG----------SAAQVAKTMYANEG 260 WK + GGA+ ++ V P D IKVK+Q A K A+EG Sbjct: 5 WKDLASGTVGGAAQLV---VGHPFDTIKVKLQSQPTPAPGQLPRYTGAIDAVKQTVASEG 61 Query: 261 LGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGAC 440 YKG+ A L A + A L + R + + G PL + Q+ G AG + Sbjct: 62 TKGLYKGMGAPLATVAAF-NAVLFTVRGQMEGLLRSEAGVPLTISQQFVAGAGAGFAVSF 120 Query: 441 VGSPADLALIRMQADSTLPAAQR--------RHYKNAFHALYRITADEGVLALWKGAGPT 596 + P +L R+QA L A ++ A + + ++ G L+KG PT Sbjct: 121 LACPTELIKCRLQAQGALAGASTTSSVVAAVKYGGPMDVARHVLRSEGGARGLFKGLFPT 180 Query: 597 VVRAMSLNMGMLASYD 644 R + N M A+Y+ Sbjct: 181 FAREVPGNATMFAAYE 196 Score = 45.8 bits (107), Expect = 1e-04 Identities = 45/216 (20%), Positives = 79/216 (36%), Gaps = 18/216 (8%) Frame = +3 Query: 57 RKEMADAKQQQAAAPTGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQ---------- 206 R +M + +A P + + FV G +G + + P ++IK ++Q Sbjct: 87 RGQMEGLLRSEAGVPLTI---SQQFVAGAGAGFAVSFLACPTELIKCRLQAQGALAGAST 143 Query: 207 -------LGEGSAAQVAKTMYANEG-LGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAI 362 + G VA+ + +EG +KGL R+ ++ Sbjct: 144 TSSVVAAVKYGGPMDVARHVLRSEGGARGLFKGLFPTFAREVPGNATMFAAYEAFKRFLA 203 Query: 363 EANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALY 542 +D L G AGA + P D+ +Q D + Y + A Sbjct: 204 GGSDTSSLGQGSLIMAGGVAGASFWGIVYPTDVVKSVLQVDDY----KNPRYTGSMDAFR 259 Query: 543 RITADEGVLALWKGAGPTVVRAMSLNMGMLASYDQS 650 +I EGV L+KG GP + R++ N +Y+ + Sbjct: 260 KILKSEGVKGLYKGFGPAMARSVPANAACFLAYEMT 295
>MCATL_MOUSE (Q8BL03) Mitchondrial carnitine/acylcarnitine carrier protein CACL| (CACT-like) (Solute carrier family 25 member 29) Length = 306 Score = 55.1 bits (131), Expect = 2e-07 Identities = 48/165 (29%), Positives = 77/165 (46%), Gaps = 6/165 (3%) Frame = +3 Query: 129 FVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTMYA------NEGLGSFYKGLSA 290 F+ G A G+ V P D++KV++Q+ Q T++ E + YKGL + Sbjct: 5 FLAGCAGGVAGVIVGHPFDIVKVRLQVQSTEKPQYRGTLHCFQSIIKQESVLGLYKGLGS 64 Query: 291 GLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALI 470 L+ T+ A + + T +A+ G+ PL Q G AGAI + P +LA Sbjct: 65 PLM-GLTFINALVFGVQGNTLRAL----GQDSPLNQ-FLAGAAAGAIQCVICCPMELAKT 118 Query: 471 RMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVR 605 R+Q + PA R YK + L +I EG+ + +G T++R Sbjct: 119 RLQLQAVGPA---RTYKGSLDCLVQIYRHEGLRGINRGMVSTLLR 160 Score = 48.9 bits (115), Expect = 1e-05 Identities = 42/180 (23%), Positives = 77/180 (42%), Gaps = 7/180 (3%) Frame = +3 Query: 120 IKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAK-------TMYANEGLGSFYK 278 + F+ G A+G + + P+++ K ++QL A+ K +Y +EGL + Sbjct: 93 LNQFLAGAAAGAIQCVICCPMELAKTRLQLQAVGPARTYKGSLDCLVQIYRHEGLRGINR 152 Query: 279 GLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPAD 458 G+ + LLR+ ++ V+T +A+ G L + + G T+G P D Sbjct: 153 GMVSTLLRETPSFGVYFLTYDVMT-RAMGCEPGDRLLVPKLLLAGGTSGITSWLSTYPMD 211 Query: 459 LALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLAS 638 + R+QAD + R + Y+ EG +G T++RA +N A+ Sbjct: 212 VVKSRLQADGLQGTPRYRGIVDCMRQSYQA---EGWQVFTRGLASTLLRAFPVNAATFAT 268 Score = 43.1 bits (100), Expect = 7e-04 Identities = 22/70 (31%), Positives = 32/70 (45%) Frame = +3 Query: 411 GLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAG 590 G G G VG P D+ +R+Q ST ++ Y+ H I E VL L+KG G Sbjct: 8 GCAGGVAGVIVGHPFDIVKVRLQVQST----EKPQYRGTLHCFQSIIKQESVLGLYKGLG 63 Query: 591 PTVVRAMSLN 620 ++ +N Sbjct: 64 SPLMGLTFIN 73 Score = 32.0 bits (71), Expect = 1.7 Identities = 27/120 (22%), Positives = 51/120 (42%), Gaps = 7/120 (5%) Frame = +3 Query: 123 KPFVNGGASGMLATCVIQPIDMIKVKIQLG--EGS-----AAQVAKTMYANEGLGSFYKG 281 K + GG SG+ + P+D++K ++Q +G+ + Y EG F +G Sbjct: 191 KLLLAGGTSGITSWLSTYPMDVVKSRLQADGLQGTPRYRGIVDCMRQSYQAEGWQVFTRG 250 Query: 282 LSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADL 461 L++ LLR A + V+ + G + +A +G + G+ + P+ L Sbjct: 251 LASTLLRAFPVNAATFATVTVV----LTYTRGEEAQVDSEAALGTSPTPAGSALAQPSSL 306
>YMC1_YEAST (P32331) Carrier protein YMC1, mitochondrial precursor| Length = 307 Score = 54.7 bits (130), Expect = 2e-07 Identities = 44/173 (25%), Positives = 78/173 (45%), Gaps = 9/173 (5%) Frame = +3 Query: 114 KTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEG--SAAQVAKTMYANEGLGSFYKGLS 287 + +K + G A G+ V QP D KV++Q +A +V + + ANEG FYKG Sbjct: 24 RVVKDLLAGTAGGIAQVLVGQPFDTTKVRLQTSSTPTTAMEVVRKLLANEGPRGFYKGTL 83 Query: 288 AGLLRQATYTTARLGSFRVLTNKAIE-------ANDGRPLPLVQKAFIGLTAGAIGACVG 446 L+ + + G N+A++ A+ L L Q G+T G + + + Sbjct: 84 TPLIGVGACVSLQFG-----VNEAMKRFFHHRNADMSSTLSLPQYYACGVTGGIVNSFLA 138 Query: 447 SPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVR 605 SP + IR+Q + + +K + ++ ++ AL +G PT++R Sbjct: 139 SPIEHVRIRLQTQT--GSGTNAEFKGPLECIKKLRHNK---ALLRGLTPTILR 186 Score = 47.0 bits (110), Expect = 5e-05 Identities = 26/76 (34%), Positives = 39/76 (51%), Gaps = 7/76 (9%) Frame = +3 Query: 138 GGASGMLATCVIQPIDMIKVKIQLGE-------GSAAQVAKTMYANEGLGSFYKGLSAGL 296 G SG ++ P+D+IK +Q S + VAKT+YAN G+G+F+KG + Sbjct: 226 GALSGTALWLMVYPLDVIKSVMQTDNLQKPKFGNSISSVAKTLYANGGIGAFFKGFGPTM 285 Query: 297 LRQATYTTARLGSFRV 344 LR A A +F + Sbjct: 286 LRAAPANGATFATFEL 301 Score = 41.2 bits (95), Expect = 0.003 Identities = 39/186 (20%), Positives = 82/186 (44%), Gaps = 12/186 (6%) Frame = +3 Query: 138 GGASGMLATCVIQPIDMIKVKIQLGEGSAA--------QVAKTMYANEGLGSFYKGLSAG 293 G G++ + + PI+ +++++Q GS + K + N+ L +GL+ Sbjct: 127 GVTGGIVNSFLASPIEHVRIRLQTQTGSGTNAEFKGPLECIKKLRHNKAL---LRGLTPT 183 Query: 294 LLRQATYTTARLGSFRVLTNKAIEANDG---RPLPLVQKAFIGLTAGAIGACVGSPADLA 464 +LR+ + L + G + +P + G +G + P D+ Sbjct: 184 ILREGHGCGTYFLVYEALIANQMNKRRGLERKDIPAWKLCIFGALSGTALWLMVYPLDVI 243 Query: 465 LIRMQADSTLPAAQRRHYKNAFHALYR-ITADEGVLALWKGAGPTVVRAMSLNMGMLASY 641 MQ D+ Q+ + N+ ++ + + A+ G+ A +KG GPT++RA N A++ Sbjct: 244 KSVMQTDNL----QKPKFGNSISSVAKTLYANGGIGAFFKGFGPTMLRAAPANGATFATF 299 Query: 642 DQSVEL 659 + ++ L Sbjct: 300 ELAMRL 305
>CMC2_HUMAN (Q9UJS0) Calcium-binding mitochondrial carrier protein Aralar2| (Mitochondrial aspartate glutamate carrier 2) (Solute carrier family 25 member 13) (Citrin) Length = 675 Score = 54.7 bits (130), Expect = 2e-07 Identities = 44/160 (27%), Positives = 70/160 (43%), Gaps = 3/160 (1%) Frame = +3 Query: 138 GGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAKTMYANEGLGSF--YKGLSAGLLRQA 308 GG +G P++++K+++Q+ GE + + LG F YKG A LR Sbjct: 435 GGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDI 494 Query: 309 TYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADS 488 ++ + + KA AN+ + G AG A + +PAD+ R+Q + Sbjct: 495 PFSAIYFPCYAHV--KASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAA 552 Query: 489 TLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRA 608 A + Y +I +EG ALWKGAG V R+ Sbjct: 553 R---AGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRS 589 Score = 46.2 bits (108), Expect = 9e-05 Identities = 45/197 (22%), Positives = 81/197 (41%), Gaps = 17/197 (8%) Frame = +3 Query: 66 MADAKQQQAAAPTG------VWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAA 227 +A+A++Q+A+ + V ++ F G +G + + PID++K ++Q + + Sbjct: 305 LAEAQRQKASGDSARPVLLQVAESAYRFGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGS 364 Query: 228 QVAKTMYAN-----------EGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEAND 374 V + MY N EG Y+GL LL A +L + +K + D Sbjct: 365 FVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMH-KD 423 Query: 375 GRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITA 554 G +PL + G AG +P ++ IR+Q + R + + Sbjct: 424 G-SVPLAAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPR-------VSALSVVR 475 Query: 555 DEGVLALWKGAGPTVVR 605 D G ++KGA +R Sbjct: 476 DLGFFGIYKGAKACFLR 492
>TXTP_BOVIN (P79110) Tricarboxylate transport protein, mitochondrial precursor| (Citrate transport protein) (CTP) (Tricarboxylate carrier protein) (Solute carrier family 25 member 1) Length = 311 Score = 53.5 bits (127), Expect = 5e-07 Identities = 47/177 (26%), Positives = 78/177 (44%), Gaps = 8/177 (4%) Frame = +3 Query: 123 KPFVNGGASGMLATCVIQPIDMIKVKIQLGEGS-------AAQVAKTMYANEGLGSFYKG 281 K + GG +G + C+ P + +K ++QL E S + + GL Y+G Sbjct: 27 KAILAGGLAGGIEICITFPTEYVKTQLQLDERSHPPRYRGIGDCVRQTVRSHGLLGLYRG 86 Query: 282 LSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGA-CVGSPAD 458 LS+ L R G+F L+N +A GR L + GL AG A V P + Sbjct: 87 LSSLLYGSIPKAAVRFGTFEFLSNHMRDA-QGR-LDSTRGLLCGLGAGVPEAVVVVCPME 144 Query: 459 LALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGM 629 ++ D T + + Y+ FH + I ++G+ ++G TV++ S N G+ Sbjct: 145 TIKVKFIHDQTSASPK---YRGFFHGVREIVREQGLKGTYQGLTATVLKQGS-NQGI 197 Score = 53.1 bits (126), Expect = 7e-07 Identities = 50/181 (27%), Positives = 78/181 (43%), Gaps = 8/181 (4%) Frame = +3 Query: 141 GASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTMY-------ANEGLGSFYKGLSAGLL 299 GA A V+ P++ IKVK + SA+ + + +GL Y+GL+A +L Sbjct: 130 GAGVPEAVVVVCPMETIKVKFIHDQTSASPKYRGFFHGVREIVREQGLKGTYQGLTATVL 189 Query: 300 RQATYTTARLGSFRVLTNKAIEANDGRPL-PLVQKAFIGLTAGAIGACVGSPADLALIRM 476 +Q + R L N N +P+ PL+ F G AGA +P D+ RM Sbjct: 190 KQGSNQGIRFFVMTSLRNWYRGDNPNKPMNPLITGVF-GAIAGAASVFGNTPLDVIKTRM 248 Query: 477 QADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYDQSVE 656 Q + Y+N +I +EG+ A +KG P + R + YD+ V+ Sbjct: 249 Q------GLEAHKYRNTLDCGLQILRNEGLKAFYKGTVPRLGRVCLDVAIVFIIYDEVVK 302 Query: 657 L 659 L Sbjct: 303 L 303
>ADT_NEUCR (P02723) ADP,ATP carrier protein (ADP/ATP translocase) (Adenine| nucleotide translocator) (ANT) Length = 313 Score = 53.1 bits (126), Expect = 7e-07 Identities = 48/197 (24%), Positives = 87/197 (44%), Gaps = 16/197 (8%) Frame = +3 Query: 105 GVWKTIKP-FVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQ-----------VAKTMY 248 G WK + +GGA+G + + +D + ++ SA + V + Sbjct: 113 GYWKWMAGNLASGGAAGATSLLFVYSLDYARTRLANDAKSAKKGGERQFNGLVDVYRKTI 172 Query: 249 ANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAG- 425 A++G+ Y+G + Y G + + +P+ LV A Sbjct: 173 ASDGIAGLYRGFGPSVAGIVVYRGLYFGLYDSI----------KPVLLVGDLKNNFLASF 222 Query: 426 AIGACVGSPADLA---LIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPT 596 A+G CV + A +A L ++ + + + YK++F A +I A EGV +L+KGAG Sbjct: 223 ALGWCVTTAAGIASYPLDTIRRRMMMTSGEAVKYKSSFDAASQIVAKEGVKSLFKGAGAN 282 Query: 597 VVRAMSLNMGMLASYDQ 647 ++R ++ G+L+ YDQ Sbjct: 283 ILRGVA-GAGVLSIYDQ 298 Score = 40.4 bits (93), Expect = 0.005 Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 2/75 (2%) Frame = +3 Query: 387 PLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQR--RHYKNAFHALYRITADE 560 P V +G + A+ +P + + +Q + A R R Y R TADE Sbjct: 12 PFVADFLMGGVSAAVSKTAAAPIERIKLLVQNQDEMIRAGRLDRRYNGIIDCFKRTTADE 71 Query: 561 GVLALWKGAGPTVVR 605 GV+ALW+G V+R Sbjct: 72 GVMALWRGNTANVIR 86 Score = 35.0 bits (79), Expect = 0.20 Identities = 46/191 (24%), Positives = 76/191 (39%), Gaps = 16/191 (8%) Frame = +3 Query: 75 AKQQQAAAPTGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGE------------G 218 A+QQ+ G+ + F+ GG S ++ PI+ IK+ +Q + Sbjct: 2 AEQQKVL---GMPPFVADFLMGGVSAAVSKTAAAPIERIKLLVQNQDEMIRAGRLDRRYN 58 Query: 219 SAAQVAKTMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAI---EANDGRPLP 389 K A+EG+ + ++G +A ++R T A +FR K + DG Sbjct: 59 GIIDCFKRTTADEGVMALWRGNTANVIRYFP-TQALNFAFRDKFKKMFGYKKDVDGYWKW 117 Query: 390 LVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRIT-ADEGV 566 + G AGA D A R+ D+ N +YR T A +G+ Sbjct: 118 MAGNLASGGAAGATSLLFVYSLDYARTRLANDAKSAKKGGERQFNGLVDVYRKTIASDGI 177 Query: 567 LALWKGAGPTV 599 L++G GP+V Sbjct: 178 AGLYRGFGPSV 188
>CMC1_PONPY (Q5RBC8) Calcium-binding mitochondrial carrier protein Aralar1| (Mitochondrial aspartate glutamate carrier 1) (Solute carrier family 25 member 12) Length = 678 Score = 52.8 bits (125), Expect = 9e-07 Identities = 46/191 (24%), Positives = 73/191 (38%), Gaps = 15/191 (7%) Frame = +3 Query: 78 KQQQAAAPTGVWKTIKP----FVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTM 245 +QQ +W I F G +G + + PID++K ++Q GS + V + M Sbjct: 309 RQQSPGLGRPIWLQIAESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELM 368 Query: 246 YAN-----------EGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPL 392 Y N EG Y+GL L+ A +L + +K + PLP Sbjct: 369 YKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVPLP- 427 Query: 393 VQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLA 572 + G AG +P ++ IR+Q + R N + D G+ Sbjct: 428 -AEVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALN-------VLRDLGIFG 479 Query: 573 LWKGAGPTVVR 605 L+KGA +R Sbjct: 480 LYKGAKACFLR 490 Score = 46.6 bits (109), Expect = 7e-05 Identities = 41/161 (25%), Positives = 69/161 (42%), Gaps = 4/161 (2%) Frame = +3 Query: 138 GGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAKTMYANEGLGSF--YKGLSAGLLRQA 308 GG +G P++++K+++Q+ GE + + LG F YKG A LR Sbjct: 433 GGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDLGIFGLYKGAKACFLRDI 492 Query: 309 TYTTARLGSFRVLTN-KAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQAD 485 ++ F V + K + A++ + + G AG A + +PAD+ R+Q Sbjct: 493 PFSAIY---FPVYAHCKLLLADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTRLQVA 549 Query: 486 STLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRA 608 + A + Y +I +EG A WKG V R+ Sbjct: 550 AR---AGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRS 587
>CMC1_HUMAN (O75746) Calcium-binding mitochondrial carrier protein Aralar1| (Mitochondrial aspartate glutamate carrier 1) (Solute carrier family 25 member 12) Length = 678 Score = 52.8 bits (125), Expect = 9e-07 Identities = 46/191 (24%), Positives = 73/191 (38%), Gaps = 15/191 (7%) Frame = +3 Query: 78 KQQQAAAPTGVWKTIKP----FVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTM 245 +QQ +W I F G +G + + PID++K ++Q GS + V + M Sbjct: 309 RQQSPGLGRPIWLQIAESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELM 368 Query: 246 YAN-----------EGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPL 392 Y N EG Y+GL L+ A +L + +K + PLP Sbjct: 369 YKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVPLP- 427 Query: 393 VQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLA 572 + G AG +P ++ IR+Q + R N + D G+ Sbjct: 428 -AEVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALN-------VLRDLGIFG 479 Query: 573 LWKGAGPTVVR 605 L+KGA +R Sbjct: 480 LYKGAKACFLR 490 Score = 47.4 bits (111), Expect = 4e-05 Identities = 44/173 (25%), Positives = 73/173 (42%), Gaps = 4/173 (2%) Frame = +3 Query: 138 GGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAKTMYANEGLGSF--YKGLSAGLLRQA 308 GG +G P++++K+++Q+ GE + + LG F YKG A LR Sbjct: 433 GGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDLGIFGLYKGAKACFLRDI 492 Query: 309 TYTTARLGSFRVLTN-KAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQAD 485 ++ F V + K + A++ + + G AG A + +PAD+ R+Q Sbjct: 493 PFSAIY---FPVYAHCKLLLADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTRLQVA 549 Query: 486 STLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYD 644 + A + Y +I +EG A WKG V R+ LA Y+ Sbjct: 550 AR---AGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLAHYE 599
>ORT1_YEAST (Q12375) Mitochondrial ornithine carrier protein| Length = 292 Score = 52.8 bits (125), Expect = 9e-07 Identities = 40/180 (22%), Positives = 76/180 (42%), Gaps = 5/180 (2%) Frame = +3 Query: 120 IKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVA----KTMYANEGLG-SFYKGL 284 I +NG +G + P D +KV++Q + K Y NEG+ F++G+ Sbjct: 14 ILDIINGSIAGACGKVIEFPFDTVKVRLQTQASNVFPTTWSCIKFTYQNEGIARGFFQGI 73 Query: 285 SAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLA 464 ++ L+ S+ + K +E + PL Q G AG+ + V +P +L Sbjct: 74 ASPLVGACLENATLFVSYNQCS-KFLEKHTN-VFPLGQILISGGVAGSCASLVLTPVELV 131 Query: 465 LIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYD 644 ++Q + A+ + + + I + G+ LW+G T +R + A+Y+ Sbjct: 132 KCKLQVANLQVASAKTKHTKVLPTIKAIITERGLAGLWQGQSGTFIRESFGGVAWFATYE 191 Score = 41.6 bits (96), Expect = 0.002 Identities = 37/197 (18%), Positives = 85/197 (43%), Gaps = 16/197 (8%) Frame = +3 Query: 102 TGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQ----------VAKTMYA 251 T V+ + ++GG +G A+ V+ P++++K K+Q+ A K + Sbjct: 102 TNVFPLGQILISGGVAGSCASLVLTPVELVKCKLQVANLQVASAKTKHTKVLPTIKAIIT 161 Query: 252 NEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIG---LTA 422 GL ++G S +R++ A ++ ++ K+++ P ++ I ++ Sbjct: 162 ERGLAGLWQGQSGTFIRESFGGVAWFATYEIV-KKSLKDRHSLDDPKRDESKIWELLISG 220 Query: 423 GAIGACVGS---PADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGP 593 G+ G + PAD T+ + + + + +A+ +I G+ ++G G Sbjct: 221 GSAGLAFNASIFPAD----------TVKSVMQTEHISLTNAVKKIFGKFGLKGFYRGLGI 270 Query: 594 TVVRAMSLNMGMLASYD 644 T+ RA+ N + ++ Sbjct: 271 TLFRAVPANAAVFYIFE 287 Score = 39.3 bits (90), Expect = 0.011 Identities = 25/98 (25%), Positives = 43/98 (43%) Frame = +3 Query: 57 RKEMADAKQQQAAAPTGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVA 236 R + D K+ ++ +W+ + ++GG++G+ I P D +K +Q S Sbjct: 200 RHSLDDPKRDESK----IWELL---ISGGSAGLAFNASIFPADTVKSVMQTEHISLTNAV 252 Query: 237 KTMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLT 350 K ++ GL FY+GL L R A F L+ Sbjct: 253 KKIFGKFGLKGFYRGLGITLFRAVPANAAVFYIFETLS 290
>CMC1_CAEEL (Q21153) Probable calcium-binding mitochondrial carrier K02F3.2| Length = 707 Score = 52.0 bits (123), Expect = 2e-06 Identities = 45/177 (25%), Positives = 72/177 (40%), Gaps = 6/177 (3%) Frame = +3 Query: 132 VNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAK-----TMYANEGLGSFYKGLSAGL 296 + GG GM P++++K+++Q G Q K T+ G YKG A Sbjct: 473 IAGGTGGMCQVVFTNPLEIVKIRLQTA-GEVQQAGKKIGVFTVLKELGFLGLYKGSRACF 531 Query: 297 LRQATYTTARLGSF-RVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIR 473 LR ++ ++ A E P L AFI AG A + +PAD+ R Sbjct: 532 LRDIPFSAIYFPAYAHAKLASADEDGMNSPGTLFASAFI---AGVPAAGLVTPADVIKTR 588 Query: 474 MQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYD 644 +Q + A + Y ++ +EG ++LWKG V R+ L +Y+ Sbjct: 589 LQVAAR---AGQTTYNGVIDCARKLIKEEGPMSLWKGTAARVCRSSPQFAVTLLTYE 642 Score = 47.8 bits (112), Expect = 3e-05 Identities = 40/170 (23%), Positives = 72/170 (42%), Gaps = 11/170 (6%) Frame = +3 Query: 129 FVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTMYAN-----------EGLGSFY 275 F+ G +G + PID++K ++Q S + V + MY N EGL Y Sbjct: 373 FLLGSVAGACGATAVYPIDLVKTRMQNQRTSGSFVGEVMYKNSLDCFKKVVKFEGLLGLY 432 Query: 276 KGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPA 455 +GL ++ A +L + +K DG+ +PL + G T G +P Sbjct: 433 RGLLPQIVGVAPEKAIKLTMNDYMRDKF--TKDGK-IPLYGEIIAGGTGGMCQVVFTNPL 489 Query: 456 DLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVR 605 ++ IR+Q + A ++ ++ + + G L L+KG+ +R Sbjct: 490 EIVKIRLQTAGEVQQAGKK------IGVFTVLKELGFLGLYKGSRACFLR 533
>MPCP_BOVIN (P12234) Phosphate carrier protein, mitochondrial precursor (PTP)| (Solute carrier family 25 member 3) Length = 362 Score = 52.0 bits (123), Expect = 2e-06 Identities = 49/190 (25%), Positives = 74/190 (38%), Gaps = 11/190 (5%) Frame = +3 Query: 108 VWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSA---AQVAKTMYANEGLGSFYK 278 +W+T ++ A + P++ KV+IQ G A A MY EGL +FYK Sbjct: 159 LWRTSLYLAASASAEFFADIALAPMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYK 218 Query: 279 GLSAGLLRQATYTTARLGSFRVLTNKAI--------EANDGRPLPLVQKAFIGLTAGAIG 434 G++ +RQ YT + F T +A+ + +P LV G AG Sbjct: 219 GVAPLWMRQIPYTMMKFACFE-RTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFC 277 Query: 435 ACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMS 614 A V P ADS + + +A L R+ G +WKG ++ + Sbjct: 278 AIVSHP---------ADSVVSVLNKEKGSSASEVLKRL----GFRGVWKGLFARIIMIGT 324 Query: 615 LNMGMLASYD 644 L YD Sbjct: 325 LTALQWFIYD 334 Score = 40.0 bits (92), Expect = 0.006 Identities = 44/216 (20%), Positives = 89/216 (41%), Gaps = 9/216 (4%) Frame = +3 Query: 36 PSPARSRRKEMADAKQQQAAAPTGVWKTIKPFVNGGASGMLAT----CVIQPIDMIKVKI 203 P P R R A A ++Q + G + F+ G G+++ + P+D++K ++ Sbjct: 37 PGPPRRSRNLAAAAVEEQYSCDYGSGRF---FILCGLGGIISCGTTHTALVPLDLVKCRM 93 Query: 204 QLGEGSAAQVAK---TMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEAND 374 Q+ + +G KG + + + + G + V K + +N Sbjct: 94 QVDPQKYKSIFNGFSVTLKEDGFRGLAKGWAPTFIGYSLQGLCKFGFYEVF--KVLYSN- 150 Query: 375 GRPLPLVQKAFIGLTAGAIGACVGSP--ADLALIRMQADSTLPAAQRRHYKNAFHALYRI 548 + + A++ T+ + A + AD+AL M+A Q + A ++ Sbjct: 151 ---MLGEENAYLWRTSLYLAASASAEFFADIALAPMEAAKVRIQTQPGYANTLRDAAPKM 207 Query: 549 TADEGVLALWKGAGPTVVRAMSLNMGMLASYDQSVE 656 +EG+ A +KG P +R + M A ++++VE Sbjct: 208 YKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVE 243
>ADT1_RABIT (O46373) ADP/ATP translocase 1 (Adenine nucleotide translocator 1)| (ANT 1) (ADP,ATP carrier protein 1) (Solute carrier family 25 member 4) (30 kDa calsequestrin-binding protein) (CSQ-binding 30 kDa protein) Length = 297 Score = 51.6 bits (122), Expect = 2e-06 Identities = 45/180 (25%), Positives = 76/180 (42%), Gaps = 9/180 (5%) Frame = +3 Query: 135 NGGASGMLATCVIQPIDMIKVKI--QLGEGSAAQ-------VAKTMYANEGLGSFYKGLS 287 +GGA+G + C + P+D + ++ +G+G+A + ++ ++GL Y+G + Sbjct: 118 SGGAAGATSLCFVYPLDFARTRLAADVGKGAAQREFSGLGNCLTKIFKSDGLRGLYQGFN 177 Query: 288 AGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 467 + Y A G + T K + D + + ++ I T A+ V P D Sbjct: 178 VSVQGIIIYRAAYFGVYD--TAKGM-LPDPKNVHIIVSWMIAQTVTAVAGLVSYPFDTVR 234 Query: 468 IRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYDQ 647 RM S A Y +I DEG A +KGA V+R M +L YD+ Sbjct: 235 RRMMMQSGRKGADIM-YTGTVDCWKKIAKDEGAKAFFKGAWSNVLRGMG-GAFVLVLYDE 292 Score = 42.4 bits (98), Expect = 0.001 Identities = 41/189 (21%), Positives = 74/189 (39%), Gaps = 14/189 (7%) Frame = +3 Query: 120 IKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTMY-----------ANEGLG 266 +K F+ GG + ++ + PI+ +K+ +Q+ S A+ Y +G Sbjct: 8 LKDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFL 67 Query: 267 SFYKGLSAGLLR---QATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGA 437 SF++G A ++R A ++ + ++ + G AGA Sbjct: 68 SFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDRHKQFWRYFAGNLASGGAAGATSL 127 Query: 438 CVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSL 617 C P D A R+ AD AAQ R + + L +I +G+ L++G +V + Sbjct: 128 CFVYPLDFARTRLAADVGKGAAQ-REFSGLGNCLTKIFKSDGLRGLYQGFNVSVQGIIIY 186 Query: 618 NMGMLASYD 644 YD Sbjct: 187 RAAYFGVYD 195 Score = 30.8 bits (68), Expect = 3.7 Identities = 20/92 (21%), Positives = 38/92 (41%), Gaps = 4/92 (4%) Frame = +3 Query: 384 LPLVQKAFIGLTAGAIGACVGSPADLALIRMQAD-STLPAAQRRHYKNAFHALYRITADE 560 L ++ G A A+ +P + + +Q ++ + + YK + RI ++ Sbjct: 5 LSFLKDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQ 64 Query: 561 GVLALWKGAGPTVVR---AMSLNMGMLASYDQ 647 G L+ W+G V+R +LN Y Q Sbjct: 65 GFLSFWRGNLANVIRYFPTQALNFAFKDKYKQ 96
>MPCP_HUMAN (Q00325) Phosphate carrier protein, mitochondrial precursor (PTP)| (Solute carrier family 25 member 3) Length = 362 Score = 51.6 bits (122), Expect = 2e-06 Identities = 50/192 (26%), Positives = 75/192 (39%), Gaps = 11/192 (5%) Frame = +3 Query: 102 TGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSA---AQVAKTMYANEGLGSF 272 T +W+T ++ A + P++ KV+IQ G A A MY EGL +F Sbjct: 157 TYLWRTSLYLAASASAEFFADIALAPMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAF 216 Query: 273 YKGLSAGLLRQATYTTARLGSFRVLTNKAI--------EANDGRPLPLVQKAFIGLTAGA 428 YKG++ +RQ YT + F T +A+ + +P LV G AG Sbjct: 217 YKGVAPLWMRQIPYTMMKFACFE-RTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGV 275 Query: 429 IGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRA 608 A V P ADS + + +A L R+ G +WKG ++ Sbjct: 276 FCAIVSHP---------ADSVVSVLNKEKGSSASLVLKRL----GFKGVWKGLFARIIMI 322 Query: 609 MSLNMGMLASYD 644 +L YD Sbjct: 323 GTLTALQWFIYD 334 Score = 37.7 bits (86), Expect = 0.031 Identities = 48/221 (21%), Positives = 90/221 (40%), Gaps = 11/221 (4%) Frame = +3 Query: 27 TSSPSPA---RSRRKEMADAKQQQAAAPTGVWKTIKPFVNGGASGMLAT----CVIQPID 185 +SSP P R R A A ++Q + G + F+ G G+++ + P+D Sbjct: 31 SSSPGPTGQPRRPRNLAAAAVEEQYSCDYGSGRF---FILCGLGGIISCGTTHTALVPLD 87 Query: 186 MIKVKIQLGEGSAAQVAK---TMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNK 356 ++K ++Q+ + +G+ KG + L + + G + V K Sbjct: 88 LVKCRMQVDPQKYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGLCKFGFYEVF--K 145 Query: 357 AIEAND-GRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFH 533 + +N G + + + L A A AD+AL M+A Q + Sbjct: 146 VLYSNMLGEENTYLWRTSLYLAASASAEFF---ADIALAPMEAAKVRIQTQPGYANTLRD 202 Query: 534 ALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYDQSVE 656 A ++ +EG+ A +KG P +R + M A ++++VE Sbjct: 203 AAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVE 243
>TXTP_RAT (P32089) Tricarboxylate transport protein, mitochondrial precursor| (Citrate transport protein) (CTP) (Tricarboxylate carrier protein) (Solute carrier family 25 member 1) Length = 311 Score = 51.2 bits (121), Expect = 3e-06 Identities = 48/181 (26%), Positives = 76/181 (41%), Gaps = 8/181 (4%) Frame = +3 Query: 141 GASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTMY-------ANEGLGSFYKGLSAGLL 299 GA A V+ P++ +KVK + S+ + + +GL Y+GL+A +L Sbjct: 130 GAGVAEAVVVVCPMETVKVKFIHDQTSSNPKYRGFFHGVREIVREQGLKGTYQGLTATVL 189 Query: 300 RQATYTTARLGSFRVLTNKAIEANDGRPL-PLVQKAFIGLTAGAIGACVGSPADLALIRM 476 +Q + R L N N +P+ PL+ F G AGA +P D+ RM Sbjct: 190 KQGSNQAIRFFVMTSLRNWYQGDNPNKPMNPLITGVF-GAVAGAASVFGNTPLDVIKTRM 248 Query: 477 QADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYDQSVE 656 Q + Y+N +I +EG A +KG P + R + YD+ V+ Sbjct: 249 Q------GLEAHKYRNTLDCGVQILKNEGPKAFYKGTVPRLGRVCLDVAIVFVIYDEVVK 302 Query: 657 L 659 L Sbjct: 303 L 303
>TXTP_HUMAN (P53007) Tricarboxylate transport protein, mitochondrial precursor| (Citrate transport protein) (CTP) (Tricarboxylate carrier protein) (Solute carrier family 25 member 1) Length = 311 Score = 51.2 bits (121), Expect = 3e-06 Identities = 49/181 (27%), Positives = 76/181 (41%), Gaps = 8/181 (4%) Frame = +3 Query: 141 GASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTMY-------ANEGLGSFYKGLSAGLL 299 GA A V+ P++ IKVK + S + + +GL Y+GL+A +L Sbjct: 130 GAGVAEAVVVVCPMETIKVKFIHDQTSPNPKYRGFFHGVREIVREQGLKGTYQGLTATVL 189 Query: 300 RQATYTTARLGSFRVLTNKAIEANDGRPL-PLVQKAFIGLTAGAIGACVGSPADLALIRM 476 +Q + R L N N +P+ PL+ F G AGA +P D+ RM Sbjct: 190 KQGSNQAIRFFVMTSLRNWYRGDNPNKPMNPLITGVF-GAIAGAASVFGNTPLDVIKTRM 248 Query: 477 QADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYDQSVE 656 Q + Y+N + +I EG+ A +KG P + R + YD+ V+ Sbjct: 249 Q------GLEAHKYRNTWDCGLQILKKEGLKAFYKGTVPRLGRVCLDVAIVFVIYDEVVK 302 Query: 657 L 659 L Sbjct: 303 L 303
>ADT_CHLRE (P27080) ADP,ATP carrier protein (ADP/ATP translocase) (Adenine| nucleotide translocator) (ANT) Length = 308 Score = 51.2 bits (121), Expect = 3e-06 Identities = 46/187 (24%), Positives = 77/187 (41%), Gaps = 16/187 (8%) Frame = +3 Query: 135 NGGASGMLATCVIQPIDMIKVKIQLGEGSAAQ------------VAKTMYANEGLGSFYK 278 +GGA+G ++ + +D + ++ SA + V + A++G+ Y+ Sbjct: 118 SGGAAGAVSLSFVYSLDYARTRLANDAKSAKKGGGDRQFNGLVDVYRKTIASDGIAGLYR 177 Query: 279 GLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAG---AIGACVGS 449 G + + Y G + L + PL G IGA + S Sbjct: 178 GFNISCVGIVVYRGLYFGMYDSLKPVVLVG------PLANNFLAAFLLGWGITIGAGLAS 231 Query: 450 -PADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMG 626 P D RM S Y ++FH I +EG+ +L+KGAG ++RA++ G Sbjct: 232 YPIDTIRRRMMMTS----GSAVKYNSSFHCFQEIVKNEGMKSLFKGAGANILRAVA-GAG 286 Query: 627 MLASYDQ 647 +LA YDQ Sbjct: 287 VLAGYDQ 293
>GDC_BOVIN (Q01888) Grave disease carrier protein (GDC) (Mitochondrial solute| carrier protein homolog) (Solute carrier family 25 member 16) Length = 330 Score = 51.2 bits (121), Expect = 3e-06 Identities = 46/155 (29%), Positives = 68/155 (43%), Gaps = 20/155 (12%) Frame = +3 Query: 105 GVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQL---GEGSAAQVA---KTMYANEG-- 260 GV + + G +GM A P+DM++V++ GE + + KT+YA EG Sbjct: 124 GVSGHVHRLMAGSMAGMTAVICTYPLDMVRVRLAFQVKGEHTYTGIIHAFKTIYAKEGGF 183 Query: 261 LGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIE--------ANDGRPLPLVQKAFIGL 416 LG FY+GL +L A Y +F L + + + P LV K I L Sbjct: 184 LG-FYRGLMPTILGMAPYAGVSFFTFGTLKSVGLSYAPTLLGRPSSDNPNVLVLKTHINL 242 Query: 417 ----TAGAIGACVGSPADLALIRMQADSTLPAAQR 509 AGAI + P D+ RMQ + LP ++ Sbjct: 243 LCGGVAGAIAQTISYPFDVTRRRMQLGAVLPEFEK 277 Score = 41.6 bits (96), Expect = 0.002 Identities = 38/172 (22%), Positives = 63/172 (36%), Gaps = 11/172 (6%) Frame = +3 Query: 120 IKPFVNGGASGMLATCVIQPIDMIKVKIQLGEG-----SAAQVAKTMYANEGLGSFYKGL 284 ++ F+ GG +G A + P+D +KV +Q + + EG YKG Sbjct: 35 LRSFLAGGIAGCCAKTTVAPLDRVKVLLQAHNHHYRHLGVFSTLRAVPKKEGYLGLYKGN 94 Query: 285 SAGLLRQATYTTARLGSFR-----VLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGS 449 A ++R Y + +F + T + + V + G AG Sbjct: 95 GAMMIRIFPYGAIQFMAFEHYKTLITTKLGVSGH-------VHRLMAGSMAGMTAVICTY 147 Query: 450 PADLALIRMQADSTLPAAQRRHYKNAFHALYRITADE-GVLALWKGAGPTVV 602 P D+ +R+ Y HA I A E G L ++G PT++ Sbjct: 148 PLDMVRVRL----AFQVKGEHTYTGIIHAFKTIYAKEGGFLGFYRGLMPTIL 195 Score = 29.6 bits (65), Expect = 8.3 Identities = 20/74 (27%), Positives = 35/74 (47%), Gaps = 9/74 (12%) Frame = +3 Query: 108 VWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEG--------SAAQVAKTMYANEGL 263 V KT + GG +G +A + P D+ + ++QLG + + K +Y + G+ Sbjct: 235 VLKTHINLLCGGVAGAIAQTISYPFDVTRRRMQLGAVLPEFEKCLTMRETMKYVYGHHGI 294 Query: 264 -GSFYKGLSAGLLR 302 Y+GLS +R Sbjct: 295 RKGLYRGLSLNYIR 308
>ADT1_MOUSE (P48962) ADP/ATP translocase 1 (Adenine nucleotide translocator 1)| (ANT 1) (ADP,ATP carrier protein 1) (Solute carrier family 25 member 4) (ADP,ATP carrier protein, heart/skeletal muscle isoform T1) (mANC1) Length = 297 Score = 51.2 bits (121), Expect = 3e-06 Identities = 45/180 (25%), Positives = 75/180 (41%), Gaps = 9/180 (5%) Frame = +3 Query: 135 NGGASGMLATCVIQPIDMIKVKI--QLGEGSA-------AQVAKTMYANEGLGSFYKGLS 287 +GGA+G + C + P+D + ++ +G+GS+ ++ ++GL Y+G S Sbjct: 118 SGGAAGATSLCFVYPLDFARTRLAADVGKGSSQREFNGLGDCLTKIFKSDGLKGLYQGFS 177 Query: 288 AGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 467 + Y A G + T K + D + + ++ I + A+ V P D Sbjct: 178 VSVQGIIIYRAAYFGVYD--TAKGM-LPDPKNVHIIVSWMIAQSVTAVAGLVSYPFDTVR 234 Query: 468 IRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYDQ 647 RM S A Y +I DEG A +KGA V+R M +L YD+ Sbjct: 235 RRMMMQSGRKGADIM-YTGTLDCWRKIAKDEGANAFFKGAWSNVLRGMG-GAFVLVLYDE 292 Score = 30.4 bits (67), Expect = 4.9 Identities = 22/84 (26%), Positives = 35/84 (41%), Gaps = 8/84 (9%) Frame = +3 Query: 420 AGAIGACVGSPADLALIRMQADSTLPAAQR-----RHYKNAFHALYRITADEGVLALWKG 584 AG I A V A + R++ + A + + YK + RI ++G L+ W+G Sbjct: 13 AGGIAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSFWRG 72 Query: 585 AGPTVVR---AMSLNMGMLASYDQ 647 V+R +LN Y Q Sbjct: 73 NLANVIRYFPTQALNFAFKDKYKQ 96
>MPCP_CAEEL (P40614) Phosphate carrier protein, mitochondrial precursor (PTP)| Length = 340 Score = 51.2 bits (121), Expect = 3e-06 Identities = 46/189 (24%), Positives = 70/189 (37%), Gaps = 10/189 (5%) Frame = +3 Query: 108 VWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQV---AKTMYANEGLGSFYK 278 +++T ++ A ++ P++ KV+IQ G+ + A +Y EGL FYK Sbjct: 137 LYRTSLYLAASASAEFFADILLAPMEATKVRIQTSPGAPPTLRGCAPMIYKAEGLTGFYK 196 Query: 279 GLSAGLLRQATYTTARLGSFRVLTNKAIE-------ANDGRPLPLVQKAFIGLTAGAIGA 437 GL +RQ YT + F + A + LV G AG A Sbjct: 197 GLPPLWMRQIPYTMMKFACFEKTVEALYQYVVPKPRAECSKAEQLVVTFVAGYIAGVFCA 256 Query: 438 CVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSL 617 V PAD + ++ DS A I G +WKG P ++ +L Sbjct: 257 IVSHPADTVVSKLNQDSQATAG-------------GILKKLGFAGVWKGLVPRIIMIGTL 303 Query: 618 NMGMLASYD 644 YD Sbjct: 304 TALQWFIYD 312 Score = 38.9 bits (89), Expect = 0.014 Identities = 38/176 (21%), Positives = 71/176 (40%), Gaps = 7/176 (3%) Frame = +3 Query: 150 GMLATCVIQPIDMIKVKIQLGEGSAAQVA---KTMYANEGLGSFYKGLSAGLLRQATYTT 320 G+ T ++ P+D++K +IQ+ +A +T A EG + KG + LL + Sbjct: 55 GITHTAIV-PLDLVKCRIQVNPEKYTGIATGFRTTIAEEGARALVKGWAPTLLGYSAQGL 113 Query: 321 ARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVG----SPADLALIRMQADS 488 + G + + N + G + + + L A A +P + +R+Q Sbjct: 114 GKFGFYEIFKNVYADML-GEENAYLYRTSLYLAASASAEFFADILLAPMEATKVRIQTSP 172 Query: 489 TLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYDQSVE 656 P R + A EG+ +KG P +R + M A ++++VE Sbjct: 173 GAPPTLRGCAPMIYKA-------EGLTGFYKGLPPLWMRQIPYTMMKFACFEKTVE 221
>MFTC_MOUSE (Q8BMG8) Mitochondrial folate transporter/carrier (Solute carrier| family 25 member 32) Length = 316 Score = 51.2 bits (121), Expect = 3e-06 Identities = 41/186 (22%), Positives = 79/186 (42%), Gaps = 15/186 (8%) Frame = +3 Query: 81 QQQAAAPTGVWKTI------KPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQ---- 230 Q Q+AA + W + + V G + G+L+ + P+D++K++ + +G + Sbjct: 4 QGQSAAGSAAWSAVFRHVRYENLVAGVSGGVLSNLALHPLDLVKIRFAVSDGLEVRPKYK 63 Query: 231 ----VAKTMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQ 398 T++ +GL Y+G++ + + + + E + PL + Sbjct: 64 GILHCLATIWKVDGLRGLYQGVTPNVWGAGLSWGLYFFFYNAIKSYKTEGRAEQLEPL-E 122 Query: 399 KAFIGLTAGAIGACVGSPADLALIRMQAD-STLPAAQRRHYKNAFHALYRITADEGVLAL 575 AGA+ C+ +P + R+ + + +R YK F AL +I EGV L Sbjct: 123 YLVSAAEAGAMTLCITNPLWVTKTRLMLQYGGVASPSQRQYKGMFDALVKIYKYEGVRGL 182 Query: 576 WKGAGP 593 +KG P Sbjct: 183 YKGFVP 188 Score = 33.1 bits (74), Expect = 0.76 Identities = 15/55 (27%), Positives = 27/55 (49%), Gaps = 3/55 (5%) Frame = +3 Query: 147 SGMLATCVIQPIDMIKVKIQ---LGEGSAAQVAKTMYANEGLGSFYKGLSAGLLR 302 S + A P +++ ++Q + G V + EG+G FYKG++ L+R Sbjct: 234 SKIFAVAATYPYQVVRARLQDQHVSYGGVTDVITKTWRKEGIGGFYKGIAPNLIR 288 Score = 30.4 bits (67), Expect = 4.9 Identities = 19/63 (30%), Positives = 26/63 (41%) Frame = +3 Query: 411 GLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAG 590 G++ G + P DL IR L R YK H L I +G+ L++G Sbjct: 29 GVSGGVLSNLALHPLDLVKIRFAVSDGLEV--RPKYKGILHCLATIWKVDGLRGLYQGVT 86 Query: 591 PTV 599 P V Sbjct: 87 PNV 89
>CMC1_MOUSE (Q8BH59) Calcium-binding mitochondrial carrier protein Aralar1| (Mitochondrial aspartate glutamate carrier 1) (Solute carrier family 25 member 12) Length = 677 Score = 50.8 bits (120), Expect = 3e-06 Identities = 45/191 (23%), Positives = 74/191 (38%), Gaps = 15/191 (7%) Frame = +3 Query: 78 KQQQAAAPTGVWKTIKP----FVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTM 245 +QQ +W I F G +G + + PID++K ++Q G+ + V + M Sbjct: 309 RQQSPGLGRPIWLQIAESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGTGSVVGELM 368 Query: 246 YAN-----------EGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPL 392 Y N EG Y+GL L+ A +L + +K + + PLP Sbjct: 369 YKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTKRDGSIPLP- 427 Query: 393 VQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLA 572 + G AG +P ++ IR+Q + R N + D G+ Sbjct: 428 -AEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALN-------VLQDLGLFG 479 Query: 573 LWKGAGPTVVR 605 L+KGA +R Sbjct: 480 LYKGAKACFLR 490 Score = 47.8 bits (112), Expect = 3e-05 Identities = 41/161 (25%), Positives = 70/161 (43%), Gaps = 4/161 (2%) Frame = +3 Query: 138 GGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAKTMYANEGLGSF--YKGLSAGLLRQA 308 GG +G P++++K+++Q+ GE + + + LG F YKG A LR Sbjct: 433 GGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNVLQDLGLFGLYKGAKACFLRDI 492 Query: 309 TYTTARLGSFRVLTN-KAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQAD 485 ++ F V + K + A++ + + G AG A + +PAD+ R+Q Sbjct: 493 PFSAIY---FPVYAHCKLLLADENGRVGGINLLTAGALAGVPAASLVTPADVIKTRLQVA 549 Query: 486 STLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRA 608 + A + Y +I +EG A WKG V R+ Sbjct: 550 AR---AGQTTYSGVVDCFRKILREEGPSAFWKGTAARVFRS 587
>MCAT_MOUSE (Q9Z2Z6) Mitochondrial carnitine/acylcarnitine carrier protein| (Carnitine/acylcarnitine translocase) (CAC) (mCAC) (Solute carrier family 25 member 20) Length = 301 Score = 50.8 bits (120), Expect = 3e-06 Identities = 50/198 (25%), Positives = 78/198 (39%), Gaps = 9/198 (4%) Frame = +3 Query: 78 KQQQAAAPTGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQ-------VA 236 K+ Q +P + F G SG+ T ++ P + IK +Q+ S A Sbjct: 97 KKLQQKSPEDELSYPQLFTAGMLSGVFTTGIMTPGERIKCLLQIQASSGENKYSGTLDCA 156 Query: 237 KTMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAI-EANDGRPLPLVQKAFIG 413 K +Y G+ FYKG L+R + ++ L N E L + + G Sbjct: 157 KKLYQEFGIRGFYKGTVLTLMRDVPASGMYFMTYEWLKNLFTPEGKSVSDLSVPRILVAG 216 Query: 414 LTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYR-ITADEGVLALWKGAG 590 AG V P D+ R Q T P + Y N F + R + +EGV +L+KG Sbjct: 217 GFAGIFNWAVAIPPDVLKSRFQ---TAPPGK---YPNGFRDVLRELIREEGVTSLYKGFN 270 Query: 591 PTVVRAMSLNMGMLASYD 644 ++RA N ++ Sbjct: 271 AVMIRAFPANAACFLGFE 288 Score = 36.6 bits (83), Expect = 0.068 Identities = 41/180 (22%), Positives = 71/180 (39%), Gaps = 16/180 (8%) Frame = +3 Query: 114 KTIKPFVN---GGASGMLATCVIQPIDMIKVKIQ-----------LGEGSAAQVAKTMYA 251 K I PF N GG GM V P+D +KV++Q + G+ KT+ Sbjct: 6 KPISPFKNLLAGGFGGMCLVFVGHPLDTVKVRLQTQPPSLSGQPPMYSGTLDCFRKTL-M 64 Query: 252 NEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAI 431 EG+ Y+G++A ++ F L K + + L Q G+ +G Sbjct: 65 REGITGLYRGMAAPIIGVTPMFAVCFFGFG-LGKKLQQKSPEDELSYPQLFTAGMLSGVF 123 Query: 432 GACVGSPAD--LALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVR 605 + +P + L+++QA S Y ++ + G+ +KG T++R Sbjct: 124 TTGIMTPGERIKCLLQIQASS-----GENKYSGTLDCAKKLYQEFGIRGFYKGTVLTLMR 178 Score = 29.6 bits (65), Expect = 8.3 Identities = 16/79 (20%), Positives = 30/79 (37%) Frame = +3 Query: 366 ANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYR 545 A++ +P+ + G G VG P D +R+Q + Q Y + Sbjct: 2 ADEPKPISPFKNLLAGGFGGMCLVFVGHPLDTVKVRLQTQPPSLSGQPPMYSGTLDCFRK 61 Query: 546 ITADEGVLALWKGAGPTVV 602 EG+ L++G ++ Sbjct: 62 TLMREGITGLYRGMAAPII 80
>MCAT_MACFA (Q8HXY2) Mitochondrial carnitine/acylcarnitine carrier protein| (Carnitine/acylcarnitine translocase) (CAC) (Solute carrier family 25 member 20) Length = 301 Score = 50.8 bits (120), Expect = 3e-06 Identities = 51/204 (25%), Positives = 83/204 (40%), Gaps = 11/204 (5%) Frame = +3 Query: 78 KQQQAAAPTGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAA-------QVA 236 K+ Q P V + F G SG+ T ++ P + IK +Q+ S A Sbjct: 97 KKLQQKHPEDVLSYPQLFAAGMLSGIFTTGIMTPGERIKCLLQIQASSGETKYTGTLDCA 156 Query: 237 KTMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGR---PLPLVQKAF 407 K +Y G+ YKG L+R + ++ + N I +G+ L + + Sbjct: 157 KKLYQEFGIRGIYKGTVVTLMRDVPASGMYFMTYEWVKN--IFTPEGKRVSELSVPRVLV 214 Query: 408 IGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYR-ITADEGVLALWKG 584 G AG V P D+ R Q T P + Y N F + R + DEGV +L+KG Sbjct: 215 AGGIAGIFNWAVAIPPDVLKSRFQ---TAPPGK---YPNGFRDVLRELIPDEGVTSLYKG 268 Query: 585 AGPTVVRAMSLNMGMLASYDQSVE 656 ++RA N ++ +++ Sbjct: 269 FNAVMIRAFPANAACFLGFEVAMK 292 Score = 33.5 bits (75), Expect = 0.58 Identities = 39/180 (21%), Positives = 72/180 (40%), Gaps = 16/180 (8%) Frame = +3 Query: 114 KTIKPFVN---GGASGMLATCVIQPIDMIKVKIQ-----------LGEGSAAQVAKTMYA 251 K I P N GG G+ V P+D +KV++Q + G+ KT++ Sbjct: 6 KPISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLF- 64 Query: 252 NEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAI 431 EG+ Y+G++A ++ F L K + + L Q G+ +G Sbjct: 65 REGIRGLYRGMAAPIIGVTPMFAVCFFGFG-LGKKLQQKHPEDVLSYPQLFAAGMLSGIF 123 Query: 432 GACVGSPAD--LALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVR 605 + +P + L+++QA S Y ++ + G+ ++KG T++R Sbjct: 124 TTGIMTPGERIKCLLQIQASS-----GETKYTGTLDCAKKLYQEFGIRGIYKGTVVTLMR 178 Score = 30.8 bits (68), Expect = 3.7 Identities = 17/79 (21%), Positives = 30/79 (37%) Frame = +3 Query: 366 ANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYR 545 A+ +P+ ++ G G VG P D +R+Q Q Y F + Sbjct: 2 ADQPKPISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRK 61 Query: 546 ITADEGVLALWKGAGPTVV 602 EG+ L++G ++ Sbjct: 62 TLFREGIRGLYRGMAAPII 80
>MCAT_HUMAN (O43772) Mitochondrial carnitine/acylcarnitine carrier protein| (Carnitine/acylcarnitine translocase) (CAC) (Solute carrier family 25 member 20) Length = 301 Score = 50.8 bits (120), Expect = 3e-06 Identities = 52/204 (25%), Positives = 83/204 (40%), Gaps = 11/204 (5%) Frame = +3 Query: 78 KQQQAAAPTGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQ-------VA 236 K+ Q P V + F G SG+ T ++ P + IK +Q+ S A Sbjct: 97 KKLQQKHPEDVLSYPQLFAAGMLSGVFTTGIMTPGERIKCLLQIQASSGESKYTGTLDCA 156 Query: 237 KTMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFI-- 410 K +Y G+ YKG L+R + ++ L N I +G+ + + I Sbjct: 157 KKLYQEFGIRGIYKGTVLTLMRDVPASGMYFMTYEWLKN--IFTPEGKRVSELSAPRILV 214 Query: 411 -GLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYR-ITADEGVLALWKG 584 G AG V P D+ R Q T P + Y N F + R + DEGV +L+KG Sbjct: 215 AGGIAGIFNWAVAIPPDVLKSRFQ---TAPPGK---YPNGFRDVLRELIRDEGVTSLYKG 268 Query: 585 AGPTVVRAMSLNMGMLASYDQSVE 656 ++RA N ++ +++ Sbjct: 269 FNAVMIRAFPANAACFLGFEVAMK 292 Score = 33.5 bits (75), Expect = 0.58 Identities = 39/180 (21%), Positives = 72/180 (40%), Gaps = 16/180 (8%) Frame = +3 Query: 114 KTIKPFVN---GGASGMLATCVIQPIDMIKVKIQ-----------LGEGSAAQVAKTMYA 251 K I P N GG G+ V P+D +KV++Q + G+ KT++ Sbjct: 6 KPISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLF- 64 Query: 252 NEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAI 431 EG+ Y+G++A ++ F L K + + L Q G+ +G Sbjct: 65 REGITGLYRGMAAPIIGVTPMFAVCFFGFG-LGKKLQQKHPEDVLSYPQLFAAGMLSGVF 123 Query: 432 GACVGSPAD--LALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVR 605 + +P + L+++QA S Y ++ + G+ ++KG T++R Sbjct: 124 TTGIMTPGERIKCLLQIQASS-----GESKYTGTLDCAKKLYQEFGIRGIYKGTVLTLMR 178 Score = 31.2 bits (69), Expect = 2.9 Identities = 17/79 (21%), Positives = 30/79 (37%) Frame = +3 Query: 366 ANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYR 545 A+ +P+ ++ G G VG P D +R+Q Q Y F + Sbjct: 2 ADQPKPISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRK 61 Query: 546 ITADEGVLALWKGAGPTVV 602 EG+ L++G ++ Sbjct: 62 TLFREGITGLYRGMAAPII 80
>ADT1_BOVIN (P02722) ADP/ATP translocase 1 (Adenine nucleotide translocator 1)| (ANT 1) (ADP,ATP carrier protein 1) (Solute carrier family 25 member 4) (ADP,ATP carrier protein, heart isoform T1) Length = 297 Score = 50.8 bits (120), Expect = 3e-06 Identities = 45/180 (25%), Positives = 76/180 (42%), Gaps = 9/180 (5%) Frame = +3 Query: 135 NGGASGMLATCVIQPIDMIKVKI--QLGEGSAAQ-------VAKTMYANEGLGSFYKGLS 287 +GGA+G + C + P+D + ++ +G+G+A + ++ ++GL Y+G + Sbjct: 118 SGGAAGATSLCFVYPLDFARTRLAADVGKGAAQREFTGLGNCITKIFKSDGLRGLYQGFN 177 Query: 288 AGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 467 + Y A G + T K + D + + ++ I T A+ V P D Sbjct: 178 VSVQGIIIYRAAYFGVYD--TAKGM-LPDPKNVHIIVSWMIAQTVTAVAGLVSYPFDTVR 234 Query: 468 IRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYDQ 647 RM S A Y +I DEG A +KGA V+R M +L YD+ Sbjct: 235 RRMMMQSGRKGADIM-YTGTVDCWRKIAKDEGPKAFFKGAWSNVLRGMG-GAFVLVLYDE 292 Score = 41.6 bits (96), Expect = 0.002 Identities = 40/189 (21%), Positives = 74/189 (39%), Gaps = 14/189 (7%) Frame = +3 Query: 120 IKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTMY-----------ANEGLG 266 +K F+ GG + ++ + PI+ +K+ +Q+ S A+ Y +G Sbjct: 8 LKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFL 67 Query: 267 SFYKGLSAGLLR---QATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGA 437 SF++G A ++R A ++ + ++ + G AGA Sbjct: 68 SFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDRHKQFWRYFAGNLASGGAAGATSL 127 Query: 438 CVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSL 617 C P D A R+ AD AAQ R + + + +I +G+ L++G +V + Sbjct: 128 CFVYPLDFARTRLAADVGKGAAQ-REFTGLGNCITKIFKSDGLRGLYQGFNVSVQGIIIY 186 Query: 618 NMGMLASYD 644 YD Sbjct: 187 RAAYFGVYD 195
>MFTC_HUMAN (Q9H2D1) Mitochondrial folate transporter/carrier (Solute carrier| family 25 member 32) Length = 315 Score = 50.4 bits (119), Expect = 5e-06 Identities = 41/187 (21%), Positives = 80/187 (42%), Gaps = 16/187 (8%) Frame = +3 Query: 81 QQQAAAPTGVWKTI------KPFVNGGASGMLATCVIQPIDMIKVKIQLGEG-------- 218 Q Q+A+ + W T+ + + G + G+L+ + P+D++K++ + +G Sbjct: 4 QGQSASGSSAWSTVFRHVRYENLIAGVSGGVLSNLALHPLDLVKIRFAVSDGLELRPKYN 63 Query: 219 SAAQVAKTMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQ 398 T++ +GL Y+G++ + + + + E R L + Sbjct: 64 GILHCLTTIWKLDGLRGLYQGVTPNIWGAGLSWGLYFFFYNAIKSYKTEGRAER-LEATE 122 Query: 399 KAFIGLTAGAIGACVGSPADLALIRM--QADSTLPAAQRRHYKNAFHALYRITADEGVLA 572 AGA+ C+ +P + R+ Q D+ + + R+ YK F L +I EGV Sbjct: 123 YLVSAAEAGAMTLCITNPLWVTKTRLMLQYDAVVNSPHRQ-YKGMFDTLVKIYKYEGVRG 181 Query: 573 LWKGAGP 593 L+KG P Sbjct: 182 LYKGFVP 188 Score = 30.0 bits (66), Expect = 6.4 Identities = 18/72 (25%), Positives = 32/72 (44%), Gaps = 4/72 (5%) Frame = +3 Query: 99 PTGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQ----LGEGSAAQVAKTMYANEGLG 266 P T++ S + A P +++ ++Q G + KT + EG+G Sbjct: 218 PEAQLSTVEYISVAALSKIFAVAATYPYQVVRARLQDQHMFYSGVIDVITKT-WRKEGVG 276 Query: 267 SFYKGLSAGLLR 302 FYKG++ L+R Sbjct: 277 GFYKGIAPNLIR 288 Score = 30.0 bits (66), Expect = 6.4 Identities = 31/172 (18%), Positives = 58/172 (33%), Gaps = 14/172 (8%) Frame = +3 Query: 132 VNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTMYAN-----------EGLGSFYK 278 V+ +G + C+ P+ + K ++ L + Y EG+ YK Sbjct: 125 VSAAEAGAMTLCITNPLWVTKTRLMLQYDAVVNSPHRQYKGMFDTLVKIYKYEGVRGLYK 184 Query: 279 GLSAGLLRQATYTTARLGSFRVLT---NKAIEANDGRPLPLVQKAFIGLTAGAIGACVGS 449 G GL ++ + ++ +L N+ I L V+ + + Sbjct: 185 GFVPGLFG-TSHGALQFMAYELLKLKYNQHINRLPEAQLSTVEYISVAALSKIFAVAATY 243 Query: 450 PADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVR 605 P + R+Q Q Y + + EGV +KG P ++R Sbjct: 244 PYQVVRARLQD-------QHMFYSGVIDVITKTWRKEGVGGFYKGIAPNLIR 288
>CMC3_CAEEL (Q19529) Probable calcium-binding mitochondrial carrier F17E5.2| Length = 531 Score = 50.4 bits (119), Expect = 5e-06 Identities = 38/172 (22%), Positives = 74/172 (43%), Gaps = 5/172 (2%) Frame = +3 Query: 102 TGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQV-----AKTMYANEGLG 266 +GVW + V GG +G ++ P D IKV +Q+ ++ ++A G+ Sbjct: 241 SGVWW--RHLVAGGVAGAMSRTCTAPFDRIKVYLQVNSTKTNKLGVVSCVHLLHAEGGIK 298 Query: 267 SFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVG 446 SF++G +++ A + + + + E G L +++ G +AGAI Sbjct: 299 SFWRGNGINVIKIAPESAMKFMCYDQIKRWMQEYKGGAELSTIERLLAGSSAGAISQTAI 358 Query: 447 SPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVV 602 P ++ R+ T + K FH +++ EG+ +KG P ++ Sbjct: 359 YPMEVMKTRLALRRT-----GQLDKGMFHFAHKMYTKEGIKCFYKGYLPNLL 405 Score = 41.2 bits (95), Expect = 0.003 Identities = 42/178 (23%), Positives = 71/178 (39%), Gaps = 13/178 (7%) Frame = +3 Query: 117 TIKPFVNGGASGMLATCVIQPIDMIKVKI------QLGEGSAAQVAKTMYANEGLGSFYK 278 TI+ + G ++G ++ I P++++K ++ QL +G A MY EG+ FYK Sbjct: 340 TIERLLAGSSAGAISQTAIYPMEVMKTRLALRRTGQLDKGMF-HFAHKMYTKEGIKCFYK 398 Query: 279 GLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLP-LVQKAFIGLTAGAIGACVGSPA 455 G LL Y L + L + + P ++ G + G P Sbjct: 399 GYLPNLLGIIPYAGIDLTVYESLKSMYTKYYTEHTEPGVLALLACGTCSSTCGQLASYPL 458 Query: 456 DLALIRMQA------DSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAM 611 L R+QA +ST P +K+ I EG L++G P ++ + Sbjct: 459 ALVRTRLQARAISPKNSTQPDTMVGQFKH-------ILQTEGFTGLYRGITPNFMKVI 509 Score = 29.6 bits (65), Expect = 8.3 Identities = 18/79 (22%), Positives = 35/79 (44%) Frame = +3 Query: 411 GLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAG 590 G AGA+ +P D + +Q +ST + + ++ + A+ G+ + W+G G Sbjct: 251 GGVAGAMSRTCTAPFDRIKVYLQVNST-----KTNKLGVVSCVHLLHAEGGIKSFWRGNG 305 Query: 591 PTVVRAMSLNMGMLASYDQ 647 V++ + YDQ Sbjct: 306 INVIKIAPESAMKFMCYDQ 324
>GDC_MOUSE (Q8C0K5) Grave disease carrier protein homolog (GDC) (Mitochondrial| solute carrier protein homolog) (Solute carrier family 25 member 16) Length = 332 Score = 50.1 bits (118), Expect = 6e-06 Identities = 45/155 (29%), Positives = 69/155 (44%), Gaps = 20/155 (12%) Frame = +3 Query: 105 GVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQL---GEGSAAQVA---KTMYANEG-- 260 GV + + G +GM A P+D+++V++ GE + + + KT+YA EG Sbjct: 126 GVSGHVHRLMAGSMAGMTAVICTYPLDVVRVRLAFQVKGEHTYSGIIHAFKTIYAKEGGF 185 Query: 261 LGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIE--------ANDGRPLPLVQKAFIGL 416 LG FY+GL +L A Y +F L + + + P LV K I L Sbjct: 186 LG-FYRGLMPTILGMAPYAGVSFFTFGTLKSVGLSYAPALLGRPSSDNPNVLVLKTHINL 244 Query: 417 ----TAGAIGACVGSPADLALIRMQADSTLPAAQR 509 AGAI + P D+ RMQ + LP ++ Sbjct: 245 LCGGVAGAIAQTISYPFDVTRRRMQLGAVLPEFEK 279 Score = 42.0 bits (97), Expect = 0.002 Identities = 38/172 (22%), Positives = 63/172 (36%), Gaps = 11/172 (6%) Frame = +3 Query: 120 IKPFVNGGASGMLATCVIQPIDMIKVKIQLGEG-----SAAQVAKTMYANEGLGSFYKGL 284 ++ F+ GG +G A + P+D +KV +Q + + EG YKG Sbjct: 37 LRSFLAGGIAGCCAKTTVAPLDRVKVLLQAHNRHYKHLGVLSTLRAVPQKEGYLGLYKGN 96 Query: 285 SAGLLRQATYTTARLGSFR-----VLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGS 449 A ++R Y + +F + T + + V + G AG Sbjct: 97 GAMMIRIFPYGAIQFMAFEHYKTFITTKLGVSGH-------VHRLMAGSMAGMTAVICTY 149 Query: 450 PADLALIRMQADSTLPAAQRRHYKNAFHALYRITADE-GVLALWKGAGPTVV 602 P D+ +R+ Y HA I A E G L ++G PT++ Sbjct: 150 PLDVVRVRL----AFQVKGEHTYSGIIHAFKTIYAKEGGFLGFYRGLMPTIL 197 Score = 32.0 bits (71), Expect = 1.7 Identities = 21/75 (28%), Positives = 31/75 (41%), Gaps = 2/75 (2%) Frame = +3 Query: 387 PLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKN--AFHALYRITADE 560 P ++ F L + G G A + + L A RHYK+ L + E Sbjct: 28 PTSRRDFYWLRSFLAGGIAGCCAKTTVAPLDRVKVLLQAHNRHYKHLGVLSTLRAVPQKE 87 Query: 561 GVLALWKGAGPTVVR 605 G L L+KG G ++R Sbjct: 88 GYLGLYKGNGAMMIR 102
>CMC2_MOUSE (Q9QXX4) Calcium-binding mitochondrial carrier protein Aralar2| (Mitochondrial aspartate glutamate carrier 2) (Solute carrier family 25 member 13) (Citrin) Length = 676 Score = 50.1 bits (118), Expect = 6e-06 Identities = 42/160 (26%), Positives = 68/160 (42%), Gaps = 3/160 (1%) Frame = +3 Query: 138 GGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAKTMYANEGLGSF--YKGLSAGLLRQA 308 GG +G P++++K+++Q+ GE + + LG F YKG A LR Sbjct: 436 GGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDI 495 Query: 309 TYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADS 488 ++ + + KA AN+ + G AG A + +PAD+ R+Q + Sbjct: 496 PFSAIYFPCYAHV--KASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAA 553 Query: 489 TLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRA 608 A + Y +I +EG ALWKG V R+ Sbjct: 554 R---AGQTTYNGVTDCFRKILREEGPKALWKGVAARVFRS 590 Score = 47.0 bits (110), Expect = 5e-05 Identities = 46/198 (23%), Positives = 82/198 (41%), Gaps = 18/198 (9%) Frame = +3 Query: 66 MADAKQQQAAAPTG-------VWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSA 224 +A+A++QQ A+ + ++ F G +G + + PID++K ++Q + Sbjct: 305 LAEAQRQQKASGDAARPFLLQLAESAYRFGLGSIAGAVGATAVYPIDLVKTRMQNQRSTG 364 Query: 225 AQVAKTMYAN-----------EGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEAN 371 + V + MY N EG Y+GL LL A +L + +K + Sbjct: 365 SFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMH-K 423 Query: 372 DGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRIT 551 DG +PL+ + F G AG +P ++ IR+Q + R + + Sbjct: 424 DG-SVPLLAEIFAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPR-------VSALSVV 475 Query: 552 ADEGVLALWKGAGPTVVR 605 D G ++KGA +R Sbjct: 476 RDLGFFGIYKGAKACFLR 493
>ADT3_YEAST (P18238) ADP,ATP carrier protein 3 (ADP/ATP translocase 3) (Adenine| nucleotide translocator 3) (ANT 3) Length = 307 Score = 50.1 bits (118), Expect = 6e-06 Identities = 47/183 (25%), Positives = 79/183 (43%), Gaps = 12/183 (6%) Frame = +3 Query: 135 NGGASGMLATCVIQPIDMIKVKIQLG-----EGSAAQ------VAKTMYANEGLGSFYKG 281 +GGA+G L+ + +D + ++ +G A Q V K ++G+ Y+G Sbjct: 122 SGGAAGALSLLFVYSLDFARTRLAADAKSSKKGGARQFNGLTDVYKKTLKSDGIAGLYRG 181 Query: 282 LSAGLLRQATYTTARLGSFRVLTNKAIEAN-DGRPLPLVQKAFIGLTAGAIGACVGSPAD 458 ++ Y G F L + + DG L ++ +T GA + P D Sbjct: 182 FMPSVVGIVVYRGLYFGMFDSLKPLVLTGSLDGSFLASFLLGWV-VTTGA--STCSYPLD 238 Query: 459 LALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLAS 638 RM S Q Y A L +I A EGV +L+KG G ++R+++ G+++ Sbjct: 239 TVRRRMMMTS----GQAVKYNGAIDCLKKIVASEGVGSLFKGCGANILRSVA-GAGVISM 293 Query: 639 YDQ 647 YDQ Sbjct: 294 YDQ 296 Score = 38.5 bits (88), Expect = 0.018 Identities = 46/194 (23%), Positives = 76/194 (39%), Gaps = 16/194 (8%) Frame = +3 Query: 69 ADAKQQQAAAPTGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQ-----LGEGS---- 221 +DAKQQ+ F+ GG S +A PI+ +K+ IQ + +G+ Sbjct: 3 SDAKQQETNFAIN-------FLMGGVSAAIAKTAASPIERVKILIQNQDEMIKQGTLDKK 55 Query: 222 ---AAQVAKTMYANEGLGSFYKGLSAGLLRQATYTTARLG---SFRVLTNKAIEANDGRP 383 K EGL SF++G +A ++R + T L ++ + +G Sbjct: 56 YSGIVDCFKRTAKQEGLISFWRGNTANVIRY--FPTQALNFAFKDKIKLMFGFKKEEGYG 113 Query: 384 LPLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRIT-ADE 560 G AGA+ D A R+ AD+ N +Y+ T + Sbjct: 114 KWFAGNLASGGAAGALSLLFVYSLDFARTRLAADAKSSKKGGARQFNGLTDVYKKTLKSD 173 Query: 561 GVLALWKGAGPTVV 602 G+ L++G P+VV Sbjct: 174 GIAGLYRGFMPSVV 187
>ADT1_RAT (Q05962) ADP/ATP translocase 1 (Adenine nucleotide translocator 1)| (ANT 1) (ADP,ATP carrier protein 1) (Solute carrier family 25 member 4) Length = 297 Score = 50.1 bits (118), Expect = 6e-06 Identities = 45/180 (25%), Positives = 75/180 (41%), Gaps = 9/180 (5%) Frame = +3 Query: 135 NGGASGMLATCVIQPIDMIKVKI--QLGEGSA-------AQVAKTMYANEGLGSFYKGLS 287 +GGA+G + C + P+D + ++ +G+GS+ ++ ++GL Y+G S Sbjct: 118 SGGAAGATSLCFVYPLDFARTRLAADVGKGSSQREFNGLGDCLTKIFKSDGLKGLYQGFS 177 Query: 288 AGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 467 + Y A G + T K + D + + ++ I + A+ V P D Sbjct: 178 VSVQGIIIYRAAYFGVYD--TAKGM-LPDPKNVHIIVSWMIAQSVTAVAGLVSYPFDTVR 234 Query: 468 IRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYDQ 647 RM S A Y +I DEG A +KGA V+R M +L YD+ Sbjct: 235 RRMMMQSGRKGADIM-YTGTVDCWRKIAKDEGRKAFFKGAWSNVLRGMG-GAFVLVLYDE 292 Score = 30.4 bits (67), Expect = 4.9 Identities = 22/84 (26%), Positives = 35/84 (41%), Gaps = 8/84 (9%) Frame = +3 Query: 420 AGAIGACVGSPADLALIRMQADSTLPAAQR-----RHYKNAFHALYRITADEGVLALWKG 584 AG I A V A + R++ + A + + YK + RI ++G L+ W+G Sbjct: 13 AGGIAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSFWRG 72 Query: 585 AGPTVVR---AMSLNMGMLASYDQ 647 V+R +LN Y Q Sbjct: 73 NLANVIRYFPTQALNFAFKDKYKQ 96
>ODC1_YEAST (Q03028) Mitochondrial 2-oxodicarboxylate carrier 1| Length = 310 Score = 49.3 bits (116), Expect = 1e-05 Identities = 41/164 (25%), Positives = 70/164 (42%), Gaps = 7/164 (4%) Frame = +3 Query: 135 NGGASGMLATCVIQPIDMIKVKIQLGEG---SAAQVAKTMYANEGLGSFYKGLSAGLLRQ 305 +G ++G + V+ P +++K+++Q + +V K G+ S + GL A + R Sbjct: 128 SGASAGAVEAFVVAPFELVKIRLQDVNSQFKTPIEVVKNSVVKGGVLSLFNGLEATIWRH 187 Query: 306 ATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVG----SPADLALIR 473 + G + A +K L AGAIG VG +P D+ R Sbjct: 188 VLWNAGYFGIIFQIRKLLPAAKTS-----TEKTRNDLIAGAIGGTVGCLLNTPFDVVKSR 242 Query: 474 MQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVR 605 +Q S R Y + ++ + +EG AL+KG P V+R Sbjct: 243 IQRSS----GPLRKYNWSLPSVLLVYREEGFKALYKGFAPKVMR 282 Score = 48.9 bits (115), Expect = 1e-05 Identities = 48/192 (25%), Positives = 81/192 (42%), Gaps = 23/192 (11%) Frame = +3 Query: 120 IKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGS-------AAQVAKTMYAN-------- 254 I F G +G+ V+ P+D++K ++QL + AA+ A Y Sbjct: 12 IYQFTAGAIAGVSELLVMYPLDVVKTRMQLQVTTKGHPAVVAAKAAVDHYTGVMDCLTKI 71 Query: 255 ---EGLGSFYKGLSAGLLRQATYTTARLG---SFRVLTNKAIEANDGRPLPLVQKAFI-- 410 EG YKG+++ +L +A + +F+ K +G + QK I Sbjct: 72 VKKEGFSHLYKGITSPILMEAPKRAIKFSGNDTFQTFYKKIFPTPNGE---MTQKIAIYS 128 Query: 411 GLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAG 590 G +AGA+ A V +P +L IR+Q ++ +K + GVL+L+ G Sbjct: 129 GASAGAVEAFVVAPFELVKIRLQDVNS-------QFKTPIEVVKNSVVKGGVLSLFNGLE 181 Query: 591 PTVVRAMSLNMG 626 T+ R + N G Sbjct: 182 ATIWRHVLWNAG 193 Score = 35.8 bits (81), Expect = 0.12 Identities = 27/79 (34%), Positives = 32/79 (40%), Gaps = 8/79 (10%) Frame = +3 Query: 372 DGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTL---PA-----AQRRHYKNA 527 D RPLP + + G AG V P D+ RMQ T PA A HY Sbjct: 5 DNRPLPFIYQFTAGAIAGVSELLVMYPLDVVKTRMQLQVTTKGHPAVVAAKAAVDHYTGV 64 Query: 528 FHALYRITADEGVLALWKG 584 L +I EG L+KG Sbjct: 65 MDCLTKIVKKEGFSHLYKG 83
>MCAT_RAT (P97521) Mitochondrial carnitine/acylcarnitine carrier protein| (Carnitine/acylcarnitine translocase) (CAC) (Solute carrier family 25 member 20) Length = 301 Score = 48.9 bits (115), Expect = 1e-05 Identities = 48/198 (24%), Positives = 78/198 (39%), Gaps = 9/198 (4%) Frame = +3 Query: 78 KQQQAAAPTGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQ-------VA 236 K+ Q +P + F G SG+ T ++ P + IK +Q+ S A Sbjct: 97 KRLQQKSPEDELTYPQLFTAGMLSGVFTTGIMTPGERIKCLLQIQASSGKNKYSGTLDCA 156 Query: 237 KTMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAI-EANDGRPLPLVQKAFIG 413 K +Y G+ FYKG + L+R + ++ L N + L + + G Sbjct: 157 KKLYQEFGIRGFYKGTALTLMRDVPASGMYFMTYEWLKNLFTPQGKSVHDLSVPRVLVAG 216 Query: 414 LTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYR-ITADEGVLALWKGAG 590 G V P D+ R Q T P + Y N F + R + +EGV +L+KG Sbjct: 217 GFRGIFNWVVAIPPDVLKSRFQ---TAPPGK---YPNGFRDVLRELIREEGVTSLYKGFN 270 Query: 591 PTVVRAMSLNMGMLASYD 644 ++RA N ++ Sbjct: 271 AVMIRAFPANAACFLGFE 288 Score = 35.0 bits (79), Expect = 0.20 Identities = 38/180 (21%), Positives = 72/180 (40%), Gaps = 16/180 (8%) Frame = +3 Query: 114 KTIKPFVN---GGASGMLATCVIQPIDMIKVKIQ-----------LGEGSAAQVAKTMYA 251 K I P N GG G+ V P+D +KV++Q + G+ KT++ Sbjct: 6 KPISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTIDCFRKTLF- 64 Query: 252 NEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAI 431 EG+ Y+G++A ++ F L + + + L Q G+ +G Sbjct: 65 REGITGLYRGMAAPIIGVTPMFAVCFFGFG-LGKRLQQKSPEDELTYPQLFTAGMLSGVF 123 Query: 432 GACVGSPAD--LALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVR 605 + +P + L+++QA S + Y ++ + G+ +KG T++R Sbjct: 124 TTGIMTPGERIKCLLQIQASS-----GKNKYSGTLDCAKKLYQEFGIRGFYKGTALTLMR 178
>MFTC_MACFA (Q95J75) Mitochondrial folate transporter/carrier (Solute carrier| family 25 member 32) Length = 315 Score = 48.9 bits (115), Expect = 1e-05 Identities = 41/187 (21%), Positives = 79/187 (42%), Gaps = 16/187 (8%) Frame = +3 Query: 81 QQQAAAPTGVWKTI------KPFVNGGASGMLATCVIQPIDMIKVKIQLGEG-------- 218 Q +A+ + W T+ + V G + G+L+ + P+D++K++ + +G Sbjct: 4 QGHSASGSSAWSTVFRHVRYENLVAGVSGGVLSNLALHPLDLVKIRFAVSDGLELRPKYN 63 Query: 219 SAAQVAKTMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQ 398 T++ +GL Y+G++ + + + + E R L + Sbjct: 64 GILHCLTTIWKLDGLRGLYQGVTPNVWGAGLSWGLYFFFYNAIKSYKTEGRAER-LEATE 122 Query: 399 KAFIGLTAGAIGACVGSPADLALIRM--QADSTLPAAQRRHYKNAFHALYRITADEGVLA 572 AGA+ C+ +P + R+ Q D+ + + R+ YK F L +I EGV Sbjct: 123 YLVSAAEAGAMTLCITNPLWVTKTRLMLQYDAVINSPHRQ-YKGMFDTLVKIYKYEGVRG 181 Query: 573 LWKGAGP 593 L+KG P Sbjct: 182 LYKGFVP 188 Score = 30.4 bits (67), Expect = 4.9 Identities = 18/72 (25%), Positives = 32/72 (44%), Gaps = 4/72 (5%) Frame = +3 Query: 99 PTGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQ----LGEGSAAQVAKTMYANEGLG 266 P T++ S + A P +++ ++Q G + KT + EG+G Sbjct: 218 PEAQLSTVEYISVAALSKIFAVAATYPYQVVRARLQDQHMFYSGVIDVITKT-WRKEGIG 276 Query: 267 SFYKGLSAGLLR 302 FYKG++ L+R Sbjct: 277 GFYKGIAPNLIR 288 Score = 29.6 bits (65), Expect = 8.3 Identities = 32/173 (18%), Positives = 62/173 (35%), Gaps = 15/173 (8%) Frame = +3 Query: 132 VNGGASGMLATCVIQPIDMIKVKIQLG------------EGSAAQVAKTMYANEGLGSFY 275 V+ +G + C+ P+ + K ++ L +G + K +Y EG+ Y Sbjct: 125 VSAAEAGAMTLCITNPLWVTKTRLMLQYDAVINSPHRQYKGMFDTLVK-IYKYEGVRGLY 183 Query: 276 KGLSAGLLRQATYTTARLGSFRVLT---NKAIEANDGRPLPLVQKAFIGLTAGAIGACVG 446 KG GL ++ + ++ +L N+ I L V+ + + Sbjct: 184 KGFVPGLFG-TSHGALQFMAYELLKLKYNQHINRLPEAQLSTVEYISVAALSKIFAVAAT 242 Query: 447 SPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVR 605 P + R+Q Q Y + + EG+ +KG P ++R Sbjct: 243 YPYQVVRARLQD-------QHMFYSGVIDVITKTWRKEGIGGFYKGIAPNLIR 288
>GDC_HUMAN (P16260) Grave disease carrier protein (GDC) (Grave disease| autoantigen) (GDA) (Mitochondrial solute carrier protein homolog) (Solute carrier family 25 member 16) Length = 332 Score = 48.5 bits (114), Expect = 2e-05 Identities = 41/154 (26%), Positives = 64/154 (41%), Gaps = 19/154 (12%) Frame = +3 Query: 105 GVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQL---GEGSAAQVA---KTMYANE-GL 263 G+ + + G +GM A P+DM++V++ GE + KT+YA E G Sbjct: 126 GISGHVHRLMAGSMAGMTAVICTDPVDMVRVRLAFQVKGEHRYTGIIHAFKTIYAKEGGF 185 Query: 264 GSFYKGLSAGLLRQATYTTARLGSFRVLTNKAI--------EANDGRPLPLVQKAFIGLT 419 FY+GL +L A Y +F L + + + P LV K + L Sbjct: 186 FGFYRGLMPTILGMAPYAGVSFFTFGTLKSVGLSHAPTLLGSPSSDNPNVLVLKTHVNLL 245 Query: 420 AG----AIGACVGSPADLALIRMQADSTLPAAQR 509 G AI + P D+ RMQ + LP ++ Sbjct: 246 CGGVARAIAQTISYPFDVTRRRMQLGTVLPEFEK 279 Score = 41.6 bits (96), Expect = 0.002 Identities = 41/175 (23%), Positives = 65/175 (37%), Gaps = 14/175 (8%) Frame = +3 Query: 120 IKPFVNGGASGMLATCVIQPIDMIKVKIQ--------LGEGSAAQVAKTMYANEGLGSFY 275 ++ F+ G +G A + P+D +KV +Q LG SA + + EG Y Sbjct: 37 LRSFLAGSIAGCCAKTTVAPLDRVKVLLQAHNHHYKHLGVFSA---LRAVPQKEGFLGLY 93 Query: 276 KGLSAGLLRQATYTTARLGSFR-----VLTNKAIEANDGRPLPLVQKAFIGLTAGAIGAC 440 KG A ++R Y + +F + T I + V + G AG Sbjct: 94 KGNGAMMIRIFPYGAIQFMAFEHYKTLITTKLGISGH-------VHRLMAGSMAGMTAVI 146 Query: 441 VGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADE-GVLALWKGAGPTVV 602 P D+ +R+ Y HA I A E G ++G PT++ Sbjct: 147 CTDPVDMVRVRL----AFQVKGEHRYTGIIHAFKTIYAKEGGFFGFYRGLMPTIL 197
>ADT_DROME (Q26365) ADP,ATP carrier protein (ADP/ATP translocase) (Adenine| nucleotide translocator) (ANT) (Stress sensitive B protein) Length = 312 Score = 48.5 bits (114), Expect = 2e-05 Identities = 41/179 (22%), Positives = 66/179 (36%), Gaps = 8/179 (4%) Frame = +3 Query: 135 NGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKT--------MYANEGLGSFYKGLSA 290 +GGA+G + C + P+D + ++ G Q T ++ ++G+ Y+G Sbjct: 134 SGGAAGATSLCFVYPLDFARTRLAADTGKGGQREFTGLGNCLTKIFKSDGIVGLYRGFGV 193 Query: 291 GLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALI 470 + Y A G + D + P+ I + V P D Sbjct: 194 SVQGIIIYRAAYFGFYDTARGM---LPDPKNTPIYISWAIAQVVTTVAGIVSYPFDTVRR 250 Query: 471 RMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYDQ 647 RM S A + YKN H I EG A +KGA ++R +L YD+ Sbjct: 251 RMMMQSGRKATE-VIYKNTLHCWATIAKQEGTGAFFKGAFSNILRGTG-GAFVLVLYDE 307
>MRS3_YEAST (P10566) Mitochondrial RNA-splicing protein MRS3| Length = 314 Score = 48.5 bits (114), Expect = 2e-05 Identities = 42/191 (21%), Positives = 79/191 (41%), Gaps = 6/191 (3%) Frame = +3 Query: 57 RKEMADAKQQQAAAPTGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAA-QV 233 +K + D+ Q P K ++G + + ++ P D IK +IQL ++ Q Sbjct: 116 KKNLIDSSDTQTHHP------FKTAISGACATTASDALMNPFDTIKQRIQLNTSASVWQT 169 Query: 234 AKTMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIG 413 K +Y +EGL +FY L+ + + T +N+ PL G Sbjct: 170 TKQIYQSEGLAAFYYSYPTTLVMNIPFAAFNFVIYESSTKFLNPSNEYNPL---IHCLCG 226 Query: 414 LTAGAIGACVGSPADL--ALIRMQADSTLPAAQRRH---YKNAFHALYRITADEGVLALW 578 +G+ A + +P D +++++ T+ R + A A+Y++ +G W Sbjct: 227 SISGSTCAAITTPLDCIKTVLQIRGSQTVSLEIMRKADTFSKAASAIYQVYGWKG---FW 283 Query: 579 KGAGPTVVRAM 611 +G P +V M Sbjct: 284 RGWKPRIVANM 294 Score = 35.4 bits (80), Expect = 0.15 Identities = 24/86 (27%), Positives = 37/86 (43%) Frame = +3 Query: 387 PLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGV 566 PL + G AG + V P D R+Q+ + A+ KN + I+ EG Sbjct: 32 PLYHQLIAGAFAGIMEHSVMFPIDALKTRIQSAN----AKSLSAKNMLSQISHISTSEGT 87 Query: 567 LALWKGAGPTVVRAMSLNMGMLASYD 644 LALWKG ++ A + +Y+ Sbjct: 88 LALWKGVQSVILGAGPAHAVYFGTYE 113 Score = 33.9 bits (76), Expect = 0.44 Identities = 35/182 (19%), Positives = 72/182 (39%), Gaps = 7/182 (3%) Frame = +3 Query: 132 VNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTMYA-------NEGLGSFYKGLSA 290 + G +G++ V+ PID +K +IQ + AK M + +EG + +KG+ + Sbjct: 38 IAGAFAGIMEHSVMFPIDALKTRIQSANAKSLS-AKNMLSQISHISTSEGTLALWKGVQS 96 Query: 291 GLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALI 470 +L G++ I+++D + + A G A + +P D Sbjct: 97 VILGAGPAHAVYFGTYEFCKKNLIDSSDTQTHHPFKTAISGACATTASDALMNPFDTIKQ 156 Query: 471 RMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYDQS 650 R+Q +++ + + +I EG+ A + T+V + Y+ S Sbjct: 157 RIQLNTS---------ASVWQTTKQIYQSEGLAAFYYSYPTTLVMNIPFAAFNFVIYESS 207 Query: 651 VE 656 + Sbjct: 208 TK 209
>CRC1_YEAST (Q12289) Mitochondrial carnitine carrier| Length = 327 Score = 48.1 bits (113), Expect = 2e-05 Identities = 43/168 (25%), Positives = 69/168 (41%), Gaps = 7/168 (4%) Frame = +3 Query: 138 GGASGMLATCVIQPIDMIKVKIQLG-EGSAAQVAKTMYANEGLGSFYKGLSAGLLRQATY 314 G S + T V P + +KV +Q +GS Q AKT+ G+ S +KG A L R Sbjct: 148 GFISAIPTTLVTAPTERVKVVLQTSSKGSFIQAAKTIVKEGGIASLFKGSLATLARDGPG 207 Query: 315 TTARLGSFRVLTN------KAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRM 476 + S+ + N +A P+ ++ G AG P D ++ Sbjct: 208 SALYFASYEISKNYLNSRQPRQDAGKDEPVNILNVCLAGGIAGMSMWLAVFPIDTIKTKL 267 Query: 477 QADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLN 620 QA ST R++ +A +Y G+ + G GP ++R+ N Sbjct: 268 QASST-----RQNMLSATKEIY--LQRGGIKGFFPGLGPALLRSFPAN 308 Score = 46.2 bits (108), Expect = 9e-05 Identities = 53/201 (26%), Positives = 81/201 (40%), Gaps = 20/201 (9%) Frame = +3 Query: 108 VWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSA-------------AQVAKTMY 248 V + IK FV GG G+ A P D+IKV+ Q G+ ++ QV T++ Sbjct: 32 VRENIKSFVAGGVGGVCAVFTGHPFDLIKVRCQNGQANSTVHAITNIIKEAKTQVKGTLF 91 Query: 249 ANEGLGSFYKGLSAGLLRQATYTTARLGSFRV------LTNKAIEANDGRPLPLVQKAFI 410 N G FYKG+ LL + V NK +N+ L + Q A Sbjct: 92 TNSVKG-FYKGVIPPLLGVTPIFAVSFWGYDVGKKLVTFNNKQGGSNE---LTMGQMAAA 147 Query: 411 GLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAF-HALYRITADEGVLALWKGA 587 G + V +P + + +Q S K +F A I + G+ +L+KG+ Sbjct: 148 GFISAIPTTLVTAPTERVKVVLQTSS----------KGSFIQAAKTIVKEGGIASLFKGS 197 Query: 588 GPTVVRAMSLNMGMLASYDQS 650 T+ R + ASY+ S Sbjct: 198 LATLARDGPGSALYFASYEIS 218
>CMC2_MACFA (Q8HXW2) Calcium-binding mitochondrial carrier protein Aralar2| (Mitochondrial aspartate glutamate carrier 2) (Solute carrier family 25 member 13) (Citrin) Length = 674 Score = 47.8 bits (112), Expect = 3e-05 Identities = 40/153 (26%), Positives = 65/153 (42%), Gaps = 3/153 (1%) Frame = +3 Query: 138 GGASGMLATCVIQPIDMIKVKIQL-GEGSAAQVAKTMYANEGLGSF--YKGLSAGLLRQA 308 GG +G P++++K+++Q+ GE + + LG F YKG A LR Sbjct: 435 GGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDI 494 Query: 309 TYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADS 488 ++ + +A AN+ + G AG A + +PAD+ R+Q + Sbjct: 495 PFSAIYFPCYAHA--RASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAA 552 Query: 489 TLPAAQRRHYKNAFHALYRITADEGVLALWKGA 587 A + Y +I +EG ALWKGA Sbjct: 553 R---AGQTTYSGVIDCFKKILREEGPKALWKGA 582 Score = 46.2 bits (108), Expect = 9e-05 Identities = 45/197 (22%), Positives = 81/197 (41%), Gaps = 17/197 (8%) Frame = +3 Query: 66 MADAKQQQAAAPTG------VWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAA 227 +A+A++Q+A+ + V ++ F G +G + + PID++K ++Q + + Sbjct: 305 LAEAQRQKASGDSARPVLLQVAESAYRFGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGS 364 Query: 228 QVAKTMYAN-----------EGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEAND 374 V + MY N EG Y+GL LL A +L + +K + D Sbjct: 365 FVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMH-KD 423 Query: 375 GRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITA 554 G +PL + G AG +P ++ IR+Q + R + + Sbjct: 424 G-SVPLAAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPR-------VSALSVVR 475 Query: 555 DEGVLALWKGAGPTVVR 605 D G ++KGA +R Sbjct: 476 DLGFFGIYKGAKACFLR 492
>ADT3_PIG (Q6QRN9) ADP/ATP translocase 3 (Adenine nucleotide translocator 2)| (ANT 3) (ADP,ATP carrier protein 3) (Solute carrier family 25 member 6) Length = 297 Score = 47.8 bits (112), Expect = 3e-05 Identities = 45/180 (25%), Positives = 71/180 (39%), Gaps = 9/180 (5%) Frame = +3 Query: 135 NGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAK---------TMYANEGLGSFYKGLS 287 +GGA+G + C + P+D + ++ G +A + + ++G+ Y+G + Sbjct: 118 SGGAAGATSLCFVYPLDFARTRLAADVGKSATEREFKGLGDCLVKITKSDGIRGLYQGFN 177 Query: 288 AGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 467 + Y A G + T K + D R +V I T A+ P D Sbjct: 178 VSVQGIIIYRAAYFGVYG--TAKGM-LPDPRNTHIVVSWMIAQTVTAVAGVFSYPFDTVR 234 Query: 468 IRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYDQ 647 RM S A YK +I DEG A +KGA V+R M +L YD+ Sbjct: 235 RRMMMQSGRKGADIM-YKGTLDCWRKIFKDEGGKAFFKGAWSNVLRGMG-GAFVLVLYDE 292 Score = 32.7 bits (73), Expect = 0.99 Identities = 22/83 (26%), Positives = 36/83 (43%), Gaps = 4/83 (4%) Frame = +3 Query: 411 GLTAGAIGACVGSPADLALIRMQAD-STLPAAQRRHYKNAFHALYRITADEGVLALWKGA 587 G A AI +P + + +Q ++ A + YK + RI ++GVL+ W+G Sbjct: 14 GGIAAAISKTAVAPIERVKLLLQVQHASKQIAADKQYKGIVDCIVRIPKEQGVLSFWRGN 73 Query: 588 GPTVVR---AMSLNMGMLASYDQ 647 V+R +LN Y Q Sbjct: 74 LANVIRYFPTQALNFAFKDKYKQ 96
>ADT1_HUMAN (P12235) ADP/ATP translocase 1 (Adenine nucleotide translocator 1)| (ANT 1) (ADP,ATP carrier protein 1) (Solute carrier family 25 member 4) (ADP,ATP carrier protein, heart/skeletal muscle isoform T1) Length = 297 Score = 47.8 bits (112), Expect = 3e-05 Identities = 44/180 (24%), Positives = 75/180 (41%), Gaps = 9/180 (5%) Frame = +3 Query: 135 NGGASGMLATCVIQPIDMIKVKI--QLGEGSAAQVAKTM-------YANEGLGSFYKGLS 287 +GGA+G + C + P+D + ++ +G+G+A + + + ++GL Y+G + Sbjct: 118 SGGAAGATSLCFVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFN 177 Query: 288 AGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 467 + Y A G + T K + D + + + I + A+ V P D Sbjct: 178 VSVQGIIIYRAAYFGVYD--TAKGM-LPDPKNVHIFVSWMIAQSVTAVAGLVSYPFDTVR 234 Query: 468 IRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYDQ 647 RM S A Y +I DEG A +KGA V+R M +L YD+ Sbjct: 235 RRMMMQSGRKGADIM-YTGTVDCWRKIAKDEGAKAFFKGAWSNVLRGMG-GAFVLVLYDE 292 Score = 45.1 bits (105), Expect = 2e-04 Identities = 42/192 (21%), Positives = 74/192 (38%), Gaps = 14/192 (7%) Frame = +3 Query: 111 WKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTMY-----------ANE 257 W +K F+ GG + ++ + PI+ +K+ +Q+ S A+ Y + Sbjct: 5 WSFLKDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQ 64 Query: 258 GLGSFYKGLSAGLLR---QATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGA 428 G SF++G A ++R A ++ L ++ + G AGA Sbjct: 65 GFLSFWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGA 124 Query: 429 IGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRA 608 C P D A R+ AD AAQ R + + +I +G+ L++G +V Sbjct: 125 TSLCFVYPLDFARTRLAADVGKGAAQ-REFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGI 183 Query: 609 MSLNMGMLASYD 644 + YD Sbjct: 184 IIYRAAYFGVYD 195
>GHC1_HUMAN (Q9H936) Mitochondrial glutamate carrier 1 (GC-1) (Glutamate/H(+)| symporter 1) (Solute carrier family 25 member 22) Length = 323 Score = 47.4 bits (111), Expect = 4e-05 Identities = 41/163 (25%), Positives = 75/163 (46%), Gaps = 7/163 (4%) Frame = +3 Query: 132 VNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTM-------YANEGLGSFYKGLSA 290 +NGG +G++ + PID+ K ++Q + + +V +M +EG Y+G + Sbjct: 13 INGGIAGLIGVTCVFPIDLAKTRLQ-NQQNGQRVYTSMSDCLIKTVRSEGYFGMYRGAAV 71 Query: 291 GLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALI 470 L +L + ++ + DG+ L L+++ G AG V +P ++ I Sbjct: 72 NLTLVTPEKAIKLAANDFFRHQL--SKDGQKLTLLKEMLAGCGAGTCQVIVTTPMEMLKI 129 Query: 471 RMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTV 599 ++Q D+ AAQR +I A +G L+ GA P+V Sbjct: 130 QLQ-DAGRIAAQR-----------KILAAQGQLSAQGGAQPSV 160 Score = 43.1 bits (100), Expect = 7e-04 Identities = 32/123 (26%), Positives = 48/123 (39%) Frame = +3 Query: 219 SAAQVAKTMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQ 398 +A Q+ + + + G+ YKGL A LLR ++ F L A++ + P Sbjct: 169 TATQLTRDLLRSRGIAGLYKGLGATLLRDVPFSVVYFPLFANLNQLGRPASEEKS-PFYV 227 Query: 399 KAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALW 578 G AG+ A +P D+ R+Q S Y +I EG A Sbjct: 228 SFLAGCVAGSAAAVAVNPCDVVKTRLQ--SLQRGVNEDTYSGILDCARKILRHEGPSAFL 285 Query: 579 KGA 587 KGA Sbjct: 286 KGA 288
>ADT3_BOVIN (P32007) ADP/ATP translocase 3 (Adenine nucleotide translocator 2)| (ANT 3) (ADP,ATP carrier protein 3) (Solute carrier family 25 member 6) (ADP,ATP carrier protein, isoform T2) (ANT 2) Length = 297 Score = 47.4 bits (111), Expect = 4e-05 Identities = 44/180 (24%), Positives = 71/180 (39%), Gaps = 9/180 (5%) Frame = +3 Query: 135 NGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAK---------TMYANEGLGSFYKGLS 287 +GGA+G + C + P+D + ++ G + + + ++G+ Y+G + Sbjct: 118 SGGAAGATSLCFVYPLDFARTRLAADVGKSGSEREFRGLGDCLVKITKSDGIRGLYQGFN 177 Query: 288 AGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 467 + Y A G + T K + D + +V I T A+ V P D Sbjct: 178 VSVQGIIIYRAAYFGIYD--TAKGM-LPDPKNTHIVVSWMIAQTVTAVAGVVSYPFDTVR 234 Query: 468 IRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYDQ 647 RM S A YK +I DEG A +KGA V+R M +L YD+ Sbjct: 235 RRMMMQSGRKGADIM-YKGTVDCWRKILKDEGGKAFFKGAWSNVLRGMG-GAFVLVLYDE 292 Score = 32.7 bits (73), Expect = 0.99 Identities = 22/83 (26%), Positives = 36/83 (43%), Gaps = 4/83 (4%) Frame = +3 Query: 411 GLTAGAIGACVGSPADLALIRMQAD-STLPAAQRRHYKNAFHALYRITADEGVLALWKGA 587 G A AI +P + + +Q ++ A + YK + RI ++GVL+ W+G Sbjct: 14 GGIAAAISKTAVAPIERVKLLLQVQHASKQIAADKQYKGIVDCIVRIPKEQGVLSFWRGN 73 Query: 588 GPTVVR---AMSLNMGMLASYDQ 647 V+R +LN Y Q Sbjct: 74 LANVIRYFPTQALNFAFKDKYKQ 96
>ADT_KLULA (P49382) ADP,ATP carrier protein (ADP/ATP translocase) (Adenine| nucleotide translocator) (ANT) Length = 305 Score = 47.4 bits (111), Expect = 4e-05 Identities = 41/182 (22%), Positives = 72/182 (39%), Gaps = 11/182 (6%) Frame = +3 Query: 135 NGGASGMLATCVIQPIDMIKVKIQLGEGSAAQ-----------VAKTMYANEGLGSFYKG 281 +GG +G L+ + +D + ++ SA + V K A++G+ Y+G Sbjct: 120 SGGLAGGLSLLFVYSLDYARTRLAADSKSAKKGGERQFNGLVDVYKKTLASDGVAGLYRG 179 Query: 282 LSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADL 461 ++ Y G + L K + + +G + P D Sbjct: 180 FLPSVVGIVVYRGLYFGLYDSL--KPLLLTGSLENSFLASFLLGWAVTTGASTASYPLDT 237 Query: 462 ALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASY 641 RM S Q Y AF A +I A EG+ +L+KG G ++R ++ G+++ Y Sbjct: 238 VRRRMMMTS----GQAVKYDGAFDAFRKIVAAEGIKSLFKGCGANILRGVA-GAGVISMY 292 Query: 642 DQ 647 DQ Sbjct: 293 DQ 294 Score = 40.4 bits (93), Expect = 0.005 Identities = 43/174 (24%), Positives = 72/174 (41%), Gaps = 16/174 (9%) Frame = +3 Query: 129 FVNGGASGMLATCVIQPIDMIKVKIQ-----LGEGSA-------AQVAKTMYANEGLGSF 272 F+ GG S ++ PI+ +K+ IQ + +GS + K A+EG+ SF Sbjct: 14 FLMGGVSAAVSKTAAAPIERVKLLIQNQDEMIKQGSLDRRYTGIVECFKRTAADEGVASF 73 Query: 273 YKGLSAGLLRQATYTTARLG---SFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACV 443 ++G +A ++R + T L ++ + +G G AG + Sbjct: 74 WRGNTANVIRY--FPTQALNFAFKDKIKAMFGFKKEEGYAKWFAGNLASGGLAGGLSLLF 131 Query: 444 GSPADLALIRMQADSTLPAAQRRHYKNAFHALYRIT-ADEGVLALWKGAGPTVV 602 D A R+ ADS N +Y+ T A +GV L++G P+VV Sbjct: 132 VYSLDYARTRLAADSKSAKKGGERQFNGLVDVYKKTLASDGVAGLYRGFLPSVV 185 Score = 31.2 bits (69), Expect = 2.9 Identities = 18/68 (26%), Positives = 29/68 (42%), Gaps = 2/68 (2%) Frame = +3 Query: 408 IGLTAGAIGACVGSPADLA--LIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 581 +G + A+ +P + LI+ Q + + R Y R ADEGV + W+ Sbjct: 16 MGGVSAAVSKTAAAPIERVKLLIQNQDEMIKQGSLDRRYTGIVECFKRTAADEGVASFWR 75 Query: 582 GAGPTVVR 605 G V+R Sbjct: 76 GNTANVIR 83
>YFL5_YEAST (P43617) Putative mitochondrial carrier YFR045W| Length = 285 Score = 47.0 bits (110), Expect = 5e-05 Identities = 29/117 (24%), Positives = 46/117 (39%) Frame = +3 Query: 237 KTMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGL 416 K MY G +F +G +A + RQ T+ + ++ ND GL Sbjct: 148 KHMYQTRGPAAFVQGTTATIFRQIANTSIQFTAYTAFKRLLQARNDK-----ASSVITGL 202 Query: 417 TAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGA 587 + P D+ RM + + + YKN + +YRI EG+ WKG+ Sbjct: 203 ATSFTLVAMTQPIDVVKTRMMSQNA-----KTEYKNTLNCMYRIFVQEGMATFWKGS 254
>MFRN1_RAT (Q66H23) Mitoferrin-1 (Mitochondrial iron transporter 1) (Solute| carrier family 25 member 37) Length = 338 Score = 47.0 bits (110), Expect = 5e-05 Identities = 39/169 (23%), Positives = 73/169 (43%), Gaps = 9/169 (5%) Frame = +3 Query: 132 VNGGASGMLATCVIQPIDMIKVKIQLGEG---SAAQVAKTMYANEGLGSFYKGLSAGLLR 302 + G + +L V+ P +++K ++Q+ SA +T++ EGLG+FY+ + L Sbjct: 148 IAGSMATLLHDAVMNPAEVVKQRLQMYNSQHQSALSCIRTVWRTEGLGAFYRSYTTQLTM 207 Query: 303 QATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADL--ALIRM 476 + + ++ L + D P + G AGA+ A +P D+ L+ Sbjct: 208 NIPFQSIHFITYEFLQEQVNPRRDYNPQSHI---ISGGLAGALAAAATTPLDVCKTLLNT 264 Query: 477 QADSTLPAA----QRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAM 611 Q + L A + NAF +Y++ G+ +KG V+ M Sbjct: 265 QENMALSLANVSGRLSGMANAFRTVYQL---NGLAGYFKGIQARVIYQM 310 Score = 36.2 bits (82), Expect = 0.089 Identities = 22/91 (24%), Positives = 38/91 (41%), Gaps = 13/91 (14%) Frame = +3 Query: 84 QQAAAPTGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVA--------- 236 Q+ P + ++GG +G LA P+D+ K + E A +A Sbjct: 223 QEQVNPRRDYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENMALSLANVSGRLSGM 282 Query: 237 ----KTMYANEGLGSFYKGLSAGLLRQATYT 317 +T+Y GL ++KG+ A ++ Q T Sbjct: 283 ANAFRTVYQLNGLAGYFKGIQARVIYQMPST 313
>MFRN1_MOUSE (Q920G8) Mitoferrin-1 (Mitochondrial iron transporter 1) (Solute| carrier family 25 member 37) (Mitochondria solute carrier protein) Length = 338 Score = 47.0 bits (110), Expect = 5e-05 Identities = 40/169 (23%), Positives = 73/169 (43%), Gaps = 9/169 (5%) Frame = +3 Query: 132 VNGGASGMLATCVIQPIDMIKVKIQLGEG---SAAQVAKTMYANEGLGSFYKGLSAGLLR 302 V G + +L V+ P +++K ++Q+ SA +T++ EGLG+FY+ + L Sbjct: 148 VAGSMATLLHDAVMNPAEVVKQRLQMYNSQHQSAFSCIRTVWRTEGLGAFYRSYTTQLTM 207 Query: 303 QATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADL--ALIRM 476 + + ++ L + D P + G AGA+ A +P D+ L+ Sbjct: 208 NIPFQSIHFITYEFLQEQVNPRRDYNPQSHI---ISGGLAGALAAAATTPLDVCKTLLNT 264 Query: 477 QADSTLPAA----QRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAM 611 Q + L A + NAF +Y++ G+ +KG V+ M Sbjct: 265 QENMALSLANVSGRLSGMANAFRTVYQL---NGLAGYFKGIQARVIYQM 310 Score = 37.0 bits (84), Expect = 0.052 Identities = 25/111 (22%), Positives = 45/111 (40%), Gaps = 17/111 (15%) Frame = +3 Query: 84 QQAAAPTGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVA--------- 236 Q+ P + ++GG +G LA P+D+ K + E A +A Sbjct: 223 QEQVNPRRDYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENMALSLANVSGRLSGM 282 Query: 237 ----KTMYANEGLGSFYKGLSAGLLRQATYTTARLGSFR----VLTNKAIE 365 +T+Y GL ++KG+ A ++ Q T + +LT + +E Sbjct: 283 ANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYILTKRQLE 333
>ORNT1_MOUSE (Q9WVD5) Mitochondrial ornithine transporter 1 (Solute carrier| family 25 member 15) Length = 301 Score = 47.0 bits (110), Expect = 5e-05 Identities = 47/192 (24%), Positives = 81/192 (42%), Gaps = 18/192 (9%) Frame = +3 Query: 138 GGASGMLATCVIQPIDMIKVKIQL-------GEGSAAQ-----VAKTMYANEGLGSFYKG 281 G + A V+ P +++K ++Q G+ +A+Q V K ++ +G FY G Sbjct: 113 GSFASAFAALVLCPTELVKCRLQTMYEMETSGKIAASQNTVWSVVKEIFRKDGPLGFYHG 172 Query: 282 LSAGLLRQATYTTARLGSFRVLTN---KAIEANDGRPLPLVQKAFIGLTAGAIGACVGS- 449 LS+ LLR+ G + + + ++ P+PL+ L+ G G C+ Sbjct: 173 LSSTLLREVPGYFFFFGGYELSRSFFASGRSKDELGPVPLM------LSGGFGGICLWLA 226 Query: 450 --PADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNM 623 P D R+Q S I +EG+ AL+ G PT++RA N Sbjct: 227 VYPVDCIKSRIQVLS-----MTGKQTGLVRTFLSIVKNEGITALYSGLKPTMIRAFPANG 281 Query: 624 GMLASYDQSVEL 659 + +Y+ S +L Sbjct: 282 ALFLAYEYSRKL 293 Score = 43.9 bits (102), Expect = 4e-04 Identities = 44/180 (24%), Positives = 67/180 (37%), Gaps = 9/180 (5%) Frame = +3 Query: 138 GGASGMLATCVIQPIDMIKVKIQ----LGEGSAAQVAKTMYANEGLGSFYKGLSAGLLRQ 305 G A G QP D +KVK+Q L G KT Y+ G FYKG S L+ Sbjct: 16 GAAGGTACVLTGQPFDTMKVKMQTFPDLYRGLTDCCLKT-YSQVGFRGFYKGTSPALIAN 74 Query: 306 ATYTTARL---GSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRM 476 + G + + K + + L +Q A G A A A V P +L R+ Sbjct: 75 IAENSVLFMCYGFCQQVVRKVVGLDQQAKLSDLQNAAAGSFASAFAALVLCPTELVKCRL 134 Query: 477 QADSTLPAAQR--RHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYDQS 650 Q + + + + + I +G L + G T++R + Y+ S Sbjct: 135 QTMYEMETSGKIAASQNTVWSVVKEIFRKDGPLGFYHGLSSTLLREVPGYFFFFGGYELS 194 Score = 32.0 bits (71), Expect = 1.7 Identities = 17/62 (27%), Positives = 31/62 (50%), Gaps = 5/62 (8%) Frame = +3 Query: 132 VNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVA-----KTMYANEGLGSFYKGLSAGL 296 ++GG G+ + P+D IK +IQ+ + Q ++ NEG+ + Y GL + Sbjct: 214 LSGGFGGICLWLAVYPVDCIKSRIQVLSMTGKQTGLVRTFLSIVKNEGITALYSGLKPTM 273 Query: 297 LR 302 +R Sbjct: 274 IR 275
>GHC1_PONPY (Q5RD81) Mitochondrial glutamate carrier 1 (GC-1) (Glutamate/H(+)| symporter 1) (Solute carrier family 25 member 22) Length = 323 Score = 47.0 bits (110), Expect = 5e-05 Identities = 40/162 (24%), Positives = 72/162 (44%), Gaps = 6/162 (3%) Frame = +3 Query: 132 VNGGASGMLATCVIQPIDMIKVKIQLGEG------SAAQVAKTMYANEGLGSFYKGLSAG 293 +NGG +G++ + PID+ K ++Q + S + +EG Y+G + Sbjct: 13 INGGIAGLIGVTCVFPIDLAKTRLQNQQNGQRMYTSMSDCLIKTIRSEGYFGMYRGAAVN 72 Query: 294 LLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIR 473 L +L + ++ + DG+ L L+++ G AG V +P ++ I+ Sbjct: 73 LTLVTPEKAIKLAANDFFRHQL--SKDGQKLTLLKEMLAGCGAGTCQVIVTTPMEMLKIQ 130 Query: 474 MQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTV 599 +Q D+ AAQR +I A +G L+ GA P+V Sbjct: 131 LQ-DAGRIAAQR-----------KILAAQGQLSAQGGAQPSV 160 Score = 41.2 bits (95), Expect = 0.003 Identities = 32/123 (26%), Positives = 47/123 (38%) Frame = +3 Query: 219 SAAQVAKTMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQ 398 +A Q+ + + + G+ YKGL A LLR + F L A++ + P Sbjct: 169 TAIQLTRDLLRSRGIAGLYKGLGATLLRDVPLSVVYFPLFANLNQLGRPASEEKS-PFYV 227 Query: 399 KAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALW 578 G AG+ A +P D+ R+Q S Y +I EG A Sbjct: 228 SFLAGCVAGSAAAVAVNPCDVVKTRLQ--SLQRGVNEDTYSGILDCARKILRHEGPSAFL 285 Query: 579 KGA 587 KGA Sbjct: 286 KGA 288
>ADT2_YEAST (P18239) ADP,ATP carrier protein 2 (ADP/ATP translocase 2) (Adenine| nucleotide translocator 2) (ANT 2) Length = 318 Score = 46.6 bits (109), Expect = 7e-05 Identities = 46/183 (25%), Positives = 79/183 (43%), Gaps = 12/183 (6%) Frame = +3 Query: 135 NGGASGMLATCVIQPIDMIKVKIQLG-----EGSAAQ------VAKTMYANEGLGSFYKG 281 +GGA+G L+ + +D + ++ +G A Q V K ++G+ Y+G Sbjct: 133 SGGAAGALSLLFVYSLDYARTRLAADSKSSKKGGARQFNGLIDVYKKTLKSDGVAGLYRG 192 Query: 282 LSAGLLRQATYTTARLGSFRVLTNKAIEAN-DGRPLPLVQKAFIGLTAGAIGACVGSPAD 458 ++ Y G + L + + +G L ++ +T GA + P D Sbjct: 193 FLPSVVGIVVYRGLYFGMYDSLKPLLLTGSLEGSFLASFLLGWV-VTTGA--STCSYPLD 249 Query: 459 LALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLAS 638 RM S Q Y AF L +I A EGV +L+KG G ++R ++ G+++ Sbjct: 250 TVRRRMMMTS----GQAVKYDGAFDCLRKIVAAEGVGSLFKGCGANILRGVA-GAGVISM 304 Query: 639 YDQ 647 YDQ Sbjct: 305 YDQ 307 Score = 37.4 bits (85), Expect = 0.040 Identities = 46/187 (24%), Positives = 73/187 (39%), Gaps = 16/187 (8%) Frame = +3 Query: 90 AAAPTGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQ-----LGEGS-------AAQV 233 A AP + F+ GG S +A PI+ +K+ IQ L +G+ Sbjct: 14 APAPKKESNFLIDFLMGGVSAAVAKTAASPIERVKLLIQNQDEMLKQGTLDRKYAGILDC 73 Query: 234 AKTMYANEGLGSFYKGLSAGLLRQATYTTARLG---SFRVLTNKAIEANDGRPLPLVQKA 404 K EG+ SF++G +A ++R + T L ++ + +G Sbjct: 74 FKRTATQEGVISFWRGNTANVIRY--FPTQALNFAFKDKIKAMFGFKKEEGYAKWFAGNL 131 Query: 405 FIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRIT-ADEGVLALWK 581 G AGA+ D A R+ ADS N +Y+ T +GV L++ Sbjct: 132 ASGGAAGALSLLFVYSLDYARTRLAADSKSSKKGGARQFNGLIDVYKKTLKSDGVAGLYR 191 Query: 582 GAGPTVV 602 G P+VV Sbjct: 192 GFLPSVV 198
>ADT2_HUMAN (P05141) ADP/ATP translocase 2 (Adenine nucleotide translocator 2)| (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) (ADP,ATP carrier protein, fibroblast isoform) Length = 297 Score = 46.6 bits (109), Expect = 7e-05 Identities = 43/180 (23%), Positives = 69/180 (38%), Gaps = 9/180 (5%) Frame = +3 Query: 135 NGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAK---------TMYANEGLGSFYKGLS 287 +GGA+G + C + P+D + ++ G A + +Y ++G+ Y+G + Sbjct: 118 SGGAAGATSLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFN 177 Query: 288 AGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 467 + Y A G + T K + D + +V I T A+ P D Sbjct: 178 VSVQGIIIYRAAYFGIYD--TAKGM-LPDPKNTHIVISWMIAQTVTAVAGLTSYPFDTVR 234 Query: 468 IRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYDQ 647 RM S Y +I DEG A +KGA V+R M +L YD+ Sbjct: 235 RRMMMQSGRKGTDIM-YTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMG-GAFVLVLYDE 292 Score = 40.8 bits (94), Expect = 0.004 Identities = 39/188 (20%), Positives = 71/188 (37%), Gaps = 14/188 (7%) Frame = +3 Query: 123 KPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTMY-----------ANEGLGS 269 K F+ GG + ++ + PI+ +K+ +Q+ S A Y +G+ S Sbjct: 9 KDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLS 68 Query: 270 FYKGLSAGLLR---QATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGAC 440 F++G A ++R A ++ + ++ G AGA C Sbjct: 69 FWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWRYFAGNLASGGAAGATSLC 128 Query: 441 VGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLN 620 P D A R+ AD A+ R ++ L +I +G+ L++G +V + Sbjct: 129 FVYPLDFARTRLAADVGKAGAE-REFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYR 187 Query: 621 MGMLASYD 644 YD Sbjct: 188 AAYFGIYD 195 Score = 31.6 bits (70), Expect = 2.2 Identities = 21/84 (25%), Positives = 36/84 (42%), Gaps = 8/84 (9%) Frame = +3 Query: 420 AGAIGACVGSPADLALIRMQADSTLPAAQR-----RHYKNAFHALYRITADEGVLALWKG 584 AG + A + A + R++ + A + + YK + RI ++GVL+ W+G Sbjct: 13 AGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLSFWRG 72 Query: 585 AGPTVVR---AMSLNMGMLASYDQ 647 V+R +LN Y Q Sbjct: 73 NLANVIRYFPTQALNFAFKDKYKQ 96
>ORNT1_HUMAN (Q9Y619) Mitochondrial ornithine transporter 1 (Solute carrier| family 25 member 15) Length = 301 Score = 46.2 bits (108), Expect = 9e-05 Identities = 44/192 (22%), Positives = 82/192 (42%), Gaps = 18/192 (9%) Frame = +3 Query: 138 GGASGMLATCVIQPIDMIKVKIQL------------GEGSAAQVAKTMYANEGLGSFYKG 281 G + A V+ P +++K ++Q + + V K++ +G FY G Sbjct: 113 GSFASAFAALVLCPTELVKCRLQTMYEMETSGKIAKSQNTVWSVIKSILRKDGPLGFYHG 172 Query: 282 LSAGLLRQATYTTARLGSFRVLTN---KAIEANDGRPLPLVQKAFIGLTAGAIGACVGS- 449 LS+ LLR+ G + + + ++ P+PL+ L+ G G C+ Sbjct: 173 LSSTLLREVPGYFFFFGGYELSRSFFASGRSKDELGPVPLM------LSGGVGGICLWLA 226 Query: 450 --PADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNM 623 P D R+Q S + ++ + F + +EG+ AL+ G PT++RA N Sbjct: 227 VYPVDCIKSRIQVLSM--SGKQAGFIRTF---INVVKNEGITALYSGLKPTMIRAFPANG 281 Query: 624 GMLASYDQSVEL 659 + +Y+ S +L Sbjct: 282 ALFLAYEYSRKL 293 Score = 43.5 bits (101), Expect = 6e-04 Identities = 44/180 (24%), Positives = 67/180 (37%), Gaps = 9/180 (5%) Frame = +3 Query: 138 GGASGMLATCVIQPIDMIKVKIQ----LGEGSAAQVAKTMYANEGLGSFYKGLSAGLLRQ 305 G A G QP D +KVK+Q L G KT Y+ G FYKG S L+ Sbjct: 16 GAAGGTACVLTGQPFDTMKVKMQTFPDLYRGLTDCCLKT-YSQVGFRGFYKGTSPALIAN 74 Query: 306 ATYTTARL---GSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRM 476 + G + + K + L +Q A G A A A V P +L R+ Sbjct: 75 IAENSVLFMCYGFCQQVVRKVAGLDKQAKLSDLQNAAAGSFASAFAALVLCPTELVKCRL 134 Query: 477 QADSTLPAAQR--RHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYDQS 650 Q + + + + + + I +G L + G T++R + Y+ S Sbjct: 135 QTMYEMETSGKIAKSQNTVWSVIKSILRKDGPLGFYHGLSSTLLREVPGYFFFFGGYELS 194 Score = 33.1 bits (74), Expect = 0.76 Identities = 18/62 (29%), Positives = 30/62 (48%), Gaps = 5/62 (8%) Frame = +3 Query: 132 VNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVA-----KTMYANEGLGSFYKGLSAGL 296 ++GG G+ + P+D IK +IQ+ S Q + NEG+ + Y GL + Sbjct: 214 LSGGVGGICLWLAVYPVDCIKSRIQVLSMSGKQAGFIRTFINVVKNEGITALYSGLKPTM 273 Query: 297 LR 302 +R Sbjct: 274 IR 275
>CMC2_CAEEL (Q20799) Probable calcium-binding mitochondrial carrier F55A11.4| Length = 588 Score = 46.2 bits (108), Expect = 9e-05 Identities = 35/171 (20%), Positives = 71/171 (41%), Gaps = 5/171 (2%) Frame = +3 Query: 105 GVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVA-----KTMYANEGLGS 269 G+W + V GGA+G ++ P D IKV +Q+ ++ K ++A G+ S Sbjct: 246 GIWW--RHLVAGGAAGAVSRTCTAPFDRIKVYLQVNSSKTNRLGVMSCLKLLHAEGGIKS 303 Query: 270 FYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGS 449 F++G +++ A + + + L + + ++ G AGAI Sbjct: 304 FWRGNGINVIKIAPESAIKFMCYDQLKRLIQKKKGNEEISTFERLCAGSAAGAISQSTIY 363 Query: 450 PADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVV 602 P ++ R+ T + + H +++ EG+ +KG P ++ Sbjct: 364 PMEVMKTRLALRKT-----GQLDRGIIHFAHKMYTKEGIRCFYKGYLPNLI 409 Score = 43.5 bits (101), Expect = 6e-04 Identities = 41/173 (23%), Positives = 66/173 (38%), Gaps = 8/173 (4%) Frame = +3 Query: 117 TIKPFVNGGASGMLATCVIQPIDMIKVKIQLG-----EGSAAQVAKTMYANEGLGSFYKG 281 T + G A+G ++ I P++++K ++ L + A MY EG+ FYKG Sbjct: 344 TFERLCAGSAAGAISQSTIYPMEVMKTRLALRKTGQLDRGIIHFAHKMYTKEGIRCFYKG 403 Query: 282 LSAGLLRQATYTTARLGSFRVLTNKAI---EANDGRPLPLVQKAFIGLTAGAIGACVGSP 452 L+ Y L + L + E N P L A G + G P Sbjct: 404 YLPNLIGIIPYAGIDLAIYETLKRTYVRYYETNSSEPGVLALLA-CGTCSSTCGQLSSYP 462 Query: 453 ADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAM 611 L R+QA S + + F I +EGV ++G P ++ + Sbjct: 463 FALVRTRLQALSITRYSPQP--DTMFGQFKYILQNEGVTGFYRGITPNFLKVI 513
>LEU5_YEAST (P38702) Mitochondrial carrier protein LEU5| Length = 357 Score = 45.8 bits (107), Expect = 1e-04 Identities = 34/123 (27%), Positives = 55/123 (44%), Gaps = 10/123 (8%) Frame = +3 Query: 138 GGASGMLATCVIQPIDMIKVKIQLGE-------GSA---AQVAKTMYANEGLGSFYKGLS 287 GG SG A +I P+D IK+ Q GS + AK ++ N+G+ F++G S Sbjct: 40 GGISGSCAKTLIAPLDRIKILFQTSNPHYTKYTGSLIGLVEAAKHIWINDGVRGFFQGHS 99 Query: 288 AGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 467 A LLR Y + ++ + N I + + ++ G AG + P DL Sbjct: 100 ATLLRIFPYAAVKFVAYEQIRNTLIPSKEFE--SHWRRLVSGSLAGLCSVFITYPLDLVR 157 Query: 468 IRM 476 +R+ Sbjct: 158 VRL 160 Score = 33.1 bits (74), Expect = 0.76 Identities = 18/85 (21%), Positives = 40/85 (47%), Gaps = 11/85 (12%) Frame = +3 Query: 81 QQQAAAPTGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGE-----------GSAA 227 Q++ P W + ++GG +GM + P ++I+ ++Q+ S + Sbjct: 255 QKKQRRPLRTWAEL---ISGGLAGMASQTAAYPFEIIRRRLQVSALSPKTMYDHKFQSIS 311 Query: 228 QVAKTMYANEGLGSFYKGLSAGLLR 302 ++A ++ G+ F+ GLS G ++ Sbjct: 312 EIAHIIFKERGVRGFFVGLSIGYIK 336
>PIC2_YEAST (P40035) Mitochondrial phosphate carrier protein 2 (Phosphate| transport protein 2) (PTP 2) (mPic 2) (Pi carrier isoform 2) Length = 300 Score = 45.8 bits (107), Expect = 1e-04 Identities = 46/174 (26%), Positives = 72/174 (41%), Gaps = 11/174 (6%) Frame = +3 Query: 156 LATCVIQPIDMIKVKIQLGE----GSAAQVAKTMYANEG-LGSFYKGLSAGLLRQATYTT 320 LA ++ P + IKVK Q + K MYA G + +FYKG+ RQ YT Sbjct: 122 LADIMLCPFEAIKVKQQTTMPPFCNNVVDGWKKMYAESGGMKAFYKGIVPLWCRQIPYTM 181 Query: 321 ARLGSFRVLTNKAI-----EANDGRPLPLVQKAFI-GLTAGAIGACVGSPADLALIRMQA 482 + SF + K + + L + +F+ G AG + A V PAD+ + ++ Sbjct: 182 CKFTSFEKIVQKIYSVLPKKKEEMNALQQISVSFVGGYLAGILCAAVSHPADVMVSKIN- 240 Query: 483 DSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYD 644 ++R+ ++ A RI G LW G +V +L YD Sbjct: 241 ------SERKANESMSVASKRIYQKIGFTGLWNGLMVRIVMIGTLTSFQWLIYD 288
>ADT2_PONPY (Q5R5A1) ADP/ATP translocase 2 (Adenine nucleotide translocator 2)| (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) Length = 297 Score = 45.8 bits (107), Expect = 1e-04 Identities = 40/168 (23%), Positives = 64/168 (38%), Gaps = 9/168 (5%) Frame = +3 Query: 135 NGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAK---------TMYANEGLGSFYKGLS 287 +GGA+G + C + P+D + ++ G A + +Y ++G+ Y+G + Sbjct: 118 SGGAAGATSLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFN 177 Query: 288 AGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 467 + Y A G + T K + D + +V I T A+ P D Sbjct: 178 VSVQGIIIYRAAYFGIYD--TAKGM-LPDPKNTHIVISWMIAQTVTAVAGLTSYPFDTVR 234 Query: 468 IRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAM 611 RM S Y +I DEG A +KGA V+R M Sbjct: 235 RRMMMQSGRKGTDIM-YTGTLDCWRKIARDEGGKAFFKGAWSNVLRGM 281 Score = 41.2 bits (95), Expect = 0.003 Identities = 39/188 (20%), Positives = 71/188 (37%), Gaps = 14/188 (7%) Frame = +3 Query: 123 KPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTMY-----------ANEGLGS 269 K F+ GG + ++ + PI+ +K+ +Q+ S A Y +G+ S Sbjct: 9 KDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLS 68 Query: 270 FYKGLSAGLLRQ---ATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGAC 440 F++G A ++R A ++ + ++ G AGA C Sbjct: 69 FWRGNLANVIRHFPTQALNFAFKDKYKQIFLGGVDKRTQFWRYFAGNLASGGAAGATSLC 128 Query: 441 VGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLN 620 P D A R+ AD A+ R ++ L +I +G+ L++G +V + Sbjct: 129 FVYPLDFARTRLAADVGKAGAE-REFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYR 187 Query: 621 MGMLASYD 644 YD Sbjct: 188 AAYFGIYD 195 Score = 31.6 bits (70), Expect = 2.2 Identities = 21/84 (25%), Positives = 36/84 (42%), Gaps = 8/84 (9%) Frame = +3 Query: 420 AGAIGACVGSPADLALIRMQADSTLPAAQR-----RHYKNAFHALYRITADEGVLALWKG 584 AG + A + A + R++ + A + + YK + RI ++GVL+ W+G Sbjct: 13 AGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLSFWRG 72 Query: 585 AGPTVVR---AMSLNMGMLASYDQ 647 V+R +LN Y Q Sbjct: 73 NLANVIRHFPTQALNFAFKDKYKQ 96
>GDC_RAT (P16261) Grave disease carrier protein (GDC) (Mitochondrial solute| carrier protein homolog) (Solute carrier family 25 member 16) (Fragment) Length = 322 Score = 45.4 bits (106), Expect = 1e-04 Identities = 41/143 (28%), Positives = 63/143 (44%), Gaps = 20/143 (13%) Frame = +3 Query: 141 GASGMLATCVIQPIDMIKVKIQL---GEGSAAQVA---KTMYANEG--LGSFYKGLSAGL 296 G M A P+D+++V++ GE + + + KT+YA EG LG FY+GL + Sbjct: 141 GKMSMTAVICTYPLDVVRVRLAFQVKGEHTYSGIIHAFKTIYAKEGGFLG-FYRGLMPTI 199 Query: 297 LRQATYTTARLGSFRVLTNKAI--------EANDGRPLPLVQKAFIGLTAG----AIGAC 440 L A Y + +F L + + + P LV K I L G AI Sbjct: 200 LGMAPYASVSFFTFGTLKSVGLSYAPTLLGRPSSDNPNVLVLKTHINLLCGGVARAIAQT 259 Query: 441 VGSPADLALIRMQADSTLPAAQR 509 + P D+ RMQ + LP ++ Sbjct: 260 ISYPFDVTRRRMQLGAVLPEFEK 282 Score = 34.7 bits (78), Expect = 0.26 Identities = 37/175 (21%), Positives = 64/175 (36%), Gaps = 14/175 (8%) Frame = +3 Query: 120 IKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVA-----KTMYANEGLGSFYKGL 284 ++ F+ G +G A + P+D +KV +Q + + + EG YKG Sbjct: 37 LRSFLAGSIAGCCAKTTVAPLDRVKVLLQAHNHHYKHLGVLSPLRAVPQKEGYLGLYKGN 96 Query: 285 SAGLLRQATYTTARLGSFR-----VLTNKAIEANDGRPLPLVQKAFIGLTAGAI---GAC 440 A ++R Y + +F + T + + V + G AG + Sbjct: 97 GAMMIRIFPYGAIQFMAFEHYKTFITTKLGVSGH-------VHRLMAGSMAGKMSMTAVI 149 Query: 441 VGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADE-GVLALWKGAGPTVV 602 P D+ +R+ Y HA I A E G L ++G PT++ Sbjct: 150 CTYPLDVVRVRL----AFQVKGEHTYSGIIHAFKTIYAKEGGFLGFYRGLMPTIL 200
>YEA6_YEAST (P39953) Putative mitochondrial carrier YEL006W| Length = 335 Score = 45.4 bits (106), Expect = 1e-04 Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 1/82 (1%) Frame = +3 Query: 402 AFIGLTAGAIGACVGSPADLALIRMQADSTLPAA-QRRHYKNAFHALYRITADEGVLALW 578 A G +GA+ A + P D+A R+QA Q +HYK F I DEG L+ Sbjct: 42 AISGALSGALSAMLVCPFDVAKTRLQAQGLQNMTHQSQHYKGFFGTFATIFKDEGAAGLY 101 Query: 579 KGAGPTVVRAMSLNMGMLASYD 644 KG PTV+ + M + YD Sbjct: 102 KGLQPTVLGYIPTLMIYFSVYD 123 Score = 43.5 bits (101), Expect = 6e-04 Identities = 42/175 (24%), Positives = 71/175 (40%), Gaps = 13/175 (7%) Frame = +3 Query: 132 VNGGASGMLATCVIQPIDMIKVKIQLG------------EGSAAQVAKTMYANEGLGSFY 275 ++G SG L+ ++ P D+ K ++Q +G A T++ +EG Y Sbjct: 43 ISGALSGALSAMLVCPFDVAKTRLQAQGLQNMTHQSQHYKGFFGTFA-TIFKDEGAAGLY 101 Query: 276 KGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRP-LPLVQKAFIGLTAGAIGACVGSP 452 KGL +L Y + F V + D P P + A +TAGAI +P Sbjct: 102 KGLQPTVL---GYIPTLMIYFSVYDFCRKYSVDIFPHSPFLSNASSAITAGAISTVATNP 158 Query: 453 ADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSL 617 + R+ + + HYK +I EG AL+ G P ++ +++ Sbjct: 159 IWVVKTRLMLQTGI-GKYSTHYKGTIDTFRKIIQQEGAKALYAGLVPALLGMLNV 212 Score = 35.4 bits (80), Expect = 0.15 Identities = 41/197 (20%), Positives = 69/197 (35%), Gaps = 22/197 (11%) Frame = +3 Query: 126 PFVNGGAS----GMLATCVIQPIDMIKVKIQLGEG---------SAAQVAKTMYANEGLG 266 PF++ +S G ++T PI ++K ++ L G + + EG Sbjct: 137 PFLSNASSAITAGAISTVATNPIWVVKTRLMLQTGIGKYSTHYKGTIDTFRKIIQQEGAK 196 Query: 267 SFYKGLSAGLLRQATYTTARLGSFRVLTNKAIE---------ANDGRPLPLVQKAFIGLT 419 + Y GL LL F + N I + D + + Sbjct: 197 ALYAGLVPALLGMLNVAI----QFPLYENLKIRFGYSESTDVSTDVTSSNFQKLILASML 252 Query: 420 AGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTV 599 + + + V P ++ RMQ S LP +RH YR EG + G + Sbjct: 253 SKMVASTVTYPHEILRTRMQLKSDLPNTVQRHLLPLIKITYR---QEGFAGFYSGFATNL 309 Query: 600 VRAMSLNMGMLASYDQS 650 VR + + L S++ S Sbjct: 310 VRTVPAAVVTLVSFEYS 326
>ADT3_HUMAN (P12236) ADP/ATP translocase 3 (Adenine nucleotide translocator 2)| (ANT 3) (ADP,ATP carrier protein 3) (Solute carrier family 25 member 6) (ADP,ATP carrier protein, isoform T2) Length = 297 Score = 45.4 bits (106), Expect = 1e-04 Identities = 44/180 (24%), Positives = 70/180 (38%), Gaps = 9/180 (5%) Frame = +3 Query: 135 NGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAK---------TMYANEGLGSFYKGLS 287 +GGA+G + C + P+D + ++ G + + + ++G+ Y+G S Sbjct: 118 SGGAAGATSLCFVYPLDFARTRLAADVGKSGTEREFRGLGDCLVKITKSDGIRGLYQGFS 177 Query: 288 AGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 467 + Y A G + T K + D + +V I T A+ V P D Sbjct: 178 VSVQGIIIYRAAYFGVYD--TAKGM-LPDPKNTHIVVSWMIAQTVTAVAGVVSYPFDTVR 234 Query: 468 IRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYDQ 647 RM S A Y +I DEG A +KGA V+R M +L YD+ Sbjct: 235 RRMMMQSGRKGADIM-YTGTVDCWRKIFRDEGGKAFFKGAWSNVLRGMG-GAFVLVLYDE 292 Score = 32.7 bits (73), Expect = 0.99 Identities = 22/83 (26%), Positives = 36/83 (43%), Gaps = 4/83 (4%) Frame = +3 Query: 411 GLTAGAIGACVGSPADLALIRMQAD-STLPAAQRRHYKNAFHALYRITADEGVLALWKGA 587 G A AI +P + + +Q ++ A + YK + RI ++GVL+ W+G Sbjct: 14 GGIAAAISKTAVAPIERVKLLLQVQHASKQIAADKQYKGIVDCIVRIPKEQGVLSFWRGN 73 Query: 588 GPTVVR---AMSLNMGMLASYDQ 647 V+R +LN Y Q Sbjct: 74 LANVIRYFPTQALNFAFKDKYKQ 96
>GHC1_MOUSE (Q9D6M3) Mitochondrial glutamate carrier 1 (GC-1) (Glutamate/H(+)| symporter 1) (Solute carrier family 25 member 22) Length = 323 Score = 44.7 bits (104), Expect = 3e-04 Identities = 41/163 (25%), Positives = 72/163 (44%), Gaps = 7/163 (4%) Frame = +3 Query: 132 VNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVA-------KTMYANEGLGSFYKGLSA 290 +NGG +G++ + PID+ K ++Q + A KT+ +EG Y+G + Sbjct: 13 INGGIAGLIGVTCVFPIDLAKTRLQNQQNGQRMYASMSDCLIKTI-RSEGYFGMYRGAAV 71 Query: 291 GLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALI 470 L +L + ++ + DG+ L L ++ G AG V +P ++ I Sbjct: 72 NLTLVTPEKAIKLAANDFFRHQL--SKDGQKLTLPKEMLAGCGAGTCQVIVTTPMEMLKI 129 Query: 471 RMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTV 599 ++Q D+ AAQR +I A + L+ GA P+V Sbjct: 130 QLQ-DAGRIAAQR-----------KILAAQAQLSAQGGAQPSV 160 Score = 42.4 bits (98), Expect = 0.001 Identities = 33/123 (26%), Positives = 47/123 (38%) Frame = +3 Query: 219 SAAQVAKTMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQ 398 +A Q+ + + N G+ YKGL A LLR ++ F L N+ + P Sbjct: 169 TATQLTRDLLRNHGIAGLYKGLGATLLRDVPFSIVYFPLFANL-NQLGRPSSEEKSPFYV 227 Query: 399 KAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALW 578 G AG+ A +P D+ R+Q S Y +I EG A Sbjct: 228 SFLAGCVAGSAAAVAVNPCDVVKTRLQ--SLERGVNEDTYSGFLDCARKIWRHEGPSAFL 285 Query: 579 KGA 587 KGA Sbjct: 286 KGA 288
>ADT2_ARATH (P40941) ADP,ATP carrier protein 2, mitochondrial precursor| (ADP/ATP translocase 2) (Adenine nucleotide translocator 2) (ANT 2) Length = 385 Score = 44.7 bits (104), Expect = 3e-04 Identities = 43/197 (21%), Positives = 84/197 (42%), Gaps = 16/197 (8%) Frame = +3 Query: 105 GVWKTIKP-FVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQ------------VAKTM 245 G WK +GGA+G + + +D + ++ SA + V K Sbjct: 184 GYWKWFAGNLASGGAAGASSLLFVYSLDYARTRLANDSKSAKKGGGERQFNGLVDVYKKT 243 Query: 246 YANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAG 425 ++G+ Y+G + Y G + + + + +Q +F + Sbjct: 244 LKSDGIAGLYRGFNISCAGIIVYRGLYFGLYDSVKPVLLTGD-------LQDSFFA--SF 294 Query: 426 AIGACVGSPADLA---LIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPT 596 A+G + + A LA + ++ + + + YK++F A +I EG +L+KGAG Sbjct: 295 ALGWLITNGAGLASYPIDTVRRRMMMTSGEAVKYKSSFDAFSQIVKKEGAKSLFKGAGAN 354 Query: 597 VVRAMSLNMGMLASYDQ 647 ++RA++ G+LA YD+ Sbjct: 355 ILRAVA-GAGVLAGYDK 370
>YM39_YEAST (Q03829) Putative mitochondrial carrier YMR166C| Length = 368 Score = 44.3 bits (103), Expect = 3e-04 Identities = 49/214 (22%), Positives = 78/214 (36%), Gaps = 35/214 (16%) Frame = +3 Query: 117 TIKPFVNGGASGMLATCVIQPIDMIKVKIQL-------------GEGSAAQVAKTMYANE 257 TI G +++ V P +++K ++QL + KT+ E Sbjct: 148 TITHLSAGFLGDFISSFVYVPSEVLKTRLQLQGRFNNPFFQSGYNYSNLRNAIKTVIKEE 207 Query: 258 GLGSFYKGLSAGLLRQATYTTARLG---SFRVLTNKAIEANDGRP--LPLVQKAFIGLTA 422 G S + G A L R ++ + FR L K IE DGR L + + G A Sbjct: 208 GFRSLFFGYKATLARDLPFSALQFAFYEKFRQLAFK-IEQKDGRDGELSIPNEILTGACA 266 Query: 423 GAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFH-----------------ALYRIT 551 G + + +P D+ R+Q P +Q + H +L + Sbjct: 267 GGLAGIITTPMDVVKTRVQTQQ--PPSQSNKSYSVTHPHVTNGRPAALSNSISLSLRTVY 324 Query: 552 ADEGVLALWKGAGPTVVRAMSLNMGMLASYDQSV 653 EGVL + G GP V + ML Y ++ Sbjct: 325 QSEGVLGFFSGVGPRFVWTSVQSSIMLLLYQMTL 358 Score = 34.3 bits (77), Expect = 0.34 Identities = 40/197 (20%), Positives = 77/197 (39%), Gaps = 13/197 (6%) Frame = +3 Query: 108 VWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEG-----SAAQVAKTMYANEGLG-S 269 +W + V+GG G + + +D +K + Q + +T++ EG+ Sbjct: 53 IWHCV---VSGGIGGKIGDSAMHSLDTVKTRQQGAPNVKKYRNMISAYRTIWLEEGVRRG 109 Query: 270 FYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGS 449 Y G A +L G++ IE + L+AG +G + S Sbjct: 110 LYGGYMAAMLGSFPSAAIFFGTYEYTKRTMIEDWQ------INDTITHLSAGFLGDFISS 163 Query: 450 ----PADLALIRMQADSTL--PAAQRRH-YKNAFHALYRITADEGVLALWKGAGPTVVRA 608 P+++ R+Q P Q + Y N +A+ + +EG +L+ G T+ R Sbjct: 164 FVYVPSEVLKTRLQLQGRFNNPFFQSGYNYSNLRNAIKTVIKEEGFRSLFFGYKATLARD 223 Query: 609 MSLNMGMLASYDQSVEL 659 + + A Y++ +L Sbjct: 224 LPFSALQFAFYEKFRQL 240
>GHC2_MOUSE (Q9DB41) Mitochondrial glutamate carrier 2 (GC-2) (Glutamate/H(+)| symporter 2) (Solute carrier family 25 member 18) (Fragment) Length = 312 Score = 44.3 bits (103), Expect = 3e-04 Identities = 32/124 (25%), Positives = 49/124 (39%) Frame = +3 Query: 219 SAAQVAKTMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQ 398 SA +A+ + +GL Y+GL A LLR ++ F L + G+ Sbjct: 162 SATLIARELLRTQGLSGLYRGLGATLLRDIPFSIIYFPLFANLNQLGVSELTGK-ASFTH 220 Query: 399 KAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALW 578 G TAG++ A +P D+ R+Q + Y ++ EG A Sbjct: 221 SFVAGCTAGSVAAVAVTPLDVLKTRIQ--TLKKGLGEDTYSGVTDCARKLWTQEGPAAFM 278 Query: 579 KGAG 590 KGAG Sbjct: 279 KGAG 282 Score = 39.3 bits (90), Expect = 0.011 Identities = 39/183 (21%), Positives = 71/183 (38%), Gaps = 25/183 (13%) Frame = +3 Query: 132 VNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQ------VAKTMYANEGLGSFYKGLSAG 293 +NGG +G++ + PID+ K ++Q +G + KT A EG Y+G + Sbjct: 10 INGGIAGLVGVTCVFPIDLAKTRLQNQQGKDVYRGMTDCLMKTARA-EGFLGMYRGAAVN 68 Query: 294 LLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIR 473 L +L + L + + DG L + G AG + P ++ I+ Sbjct: 69 LTLVTPEKAIKLAANDFL--RQLLMQDGTQRNLKMEMLAGCGAGICQVVITCPMEMLKIQ 126 Query: 474 MQADSTLPAAQR---------RHYKNAFHALYR----------ITADEGVLALWKGAGPT 596 +Q L + R Y + +R + +G+ L++G G T Sbjct: 127 LQDAGRLAVCHQASASATPTSRPYSTGSTSTHRRPSATLIARELLRTQGLSGLYRGLGAT 186 Query: 597 VVR 605 ++R Sbjct: 187 LLR 189
>ADT2_BOVIN (Q8SQH5) ADP/ATP translocase 2 (Adenine nucleotide translocator 2)| (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) Length = 297 Score = 44.3 bits (103), Expect = 3e-04 Identities = 41/180 (22%), Positives = 68/180 (37%), Gaps = 9/180 (5%) Frame = +3 Query: 135 NGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAK---------TMYANEGLGSFYKGLS 287 +GGA+G + C + P+D + ++ G A + +Y ++G+ Y+G + Sbjct: 118 SGGAAGATSLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIRGLYQGFN 177 Query: 288 AGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 467 + Y A G + T K + D + + I + A+ P D Sbjct: 178 VSVQGIIIYRAAYFGIYD--TAKGM-LPDPKNTHIFISWMIAQSVTAVAGLTSYPFDTVR 234 Query: 468 IRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYDQ 647 RM S Y +I DEG A +KGA V+R M +L YD+ Sbjct: 235 RRMMMQSGRKGTDIM-YTGTLDCWRKIARDEGAKAFFKGAWSNVLRGMG-GAFVLVLYDE 292 Score = 40.8 bits (94), Expect = 0.004 Identities = 39/188 (20%), Positives = 71/188 (37%), Gaps = 14/188 (7%) Frame = +3 Query: 123 KPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTMY-----------ANEGLGS 269 K F+ GG + ++ + PI+ +K+ +Q+ S A Y +G+ S Sbjct: 9 KDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLS 68 Query: 270 FYKGLSAGLLR---QATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGAC 440 F++G A ++R A ++ + ++ G AGA C Sbjct: 69 FWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWRYFAGNLASGGAAGATSLC 128 Query: 441 VGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLN 620 P D A R+ AD A+ R ++ L +I +G+ L++G +V + Sbjct: 129 FVYPLDFARTRLAADVGKAGAE-REFRGLGDCLVKIYKSDGIRGLYQGFNVSVQGIIIYR 187 Query: 621 MGMLASYD 644 YD Sbjct: 188 AAYFGIYD 195 Score = 31.6 bits (70), Expect = 2.2 Identities = 21/84 (25%), Positives = 36/84 (42%), Gaps = 8/84 (9%) Frame = +3 Query: 420 AGAIGACVGSPADLALIRMQADSTLPAAQR-----RHYKNAFHALYRITADEGVLALWKG 584 AG + A + A + R++ + A + + YK + RI ++GVL+ W+G Sbjct: 13 AGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLSFWRG 72 Query: 585 AGPTVVR---AMSLNMGMLASYDQ 647 V+R +LN Y Q Sbjct: 73 NLANVIRYFPTQALNFAFKDKYKQ 96
>YDE9_SCHPO (Q10442) Putative mitochondrial carrier C12B10.09| Length = 345 Score = 43.9 bits (102), Expect = 4e-04 Identities = 44/169 (26%), Positives = 72/169 (42%), Gaps = 4/169 (2%) Frame = +3 Query: 150 GMLATCVIQ-PIDMIKVKIQLGEG--SAAQVAKTMY-ANEGLGSFYKGLSAGLLRQATYT 317 G +A C+++ P ++IK + Q G S+ + +T+ +N FY G + R+ +T Sbjct: 174 GEIAACIVRVPTEVIKQRAQASGGTLSSRNILQTILKSNNVWRDFYAGYGITIAREIPFT 233 Query: 318 TARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLP 497 + + L K + + A G AG I A + +P D+ R+ + Sbjct: 234 LIQFPIWEHLKLKWRIKHSRNKNLAHEAAISGSIAGGIAAALTTPFDVVKTRI-----MT 288 Query: 498 AAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYD 644 + QR Y + I A EG LAL+KG P V+ L YD Sbjct: 289 SQQRLSY---VFTIKSIVAHEGFLALYKGIVPRVLWLSGGGAIFLGCYD 334 Score = 34.7 bits (78), Expect = 0.26 Identities = 20/76 (26%), Positives = 39/76 (51%), Gaps = 2/76 (2%) Frame = +3 Query: 132 VNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQV--AKTMYANEGLGSFYKGLSAGLLRQ 305 ++G +G +A + P D++K +I + + V K++ A+EG + YKG+ +L Sbjct: 263 ISGSIAGGIAAALTTPFDVVKTRIMTSQQRLSYVFTIKSIVAHEGFLALYKGIVPRVLWL 322 Query: 306 ATYTTARLGSFRVLTN 353 + LG + V+ N Sbjct: 323 SGGGAIFLGCYDVILN 338
>TXTP_YEAST (P38152) Tricarboxylate transport protein (Citrate transport| protein) (CTP) Length = 299 Score = 43.9 bits (102), Expect = 4e-04 Identities = 42/184 (22%), Positives = 73/184 (39%), Gaps = 16/184 (8%) Frame = +3 Query: 102 TGVWKTIKPFVNGGASGML-ATCVIQPIDMIKVKIQLGEGSAA-----------QVAKTM 245 TG + + G +G+L + + P + IK + + SA + ++ Sbjct: 103 TGELSGTRGVIAGLGAGLLESVAAVTPFEAIKTALIDDKQSATPKYHNNGRGVVRNYSSL 162 Query: 246 YANEGLGSFYKGLSAGLLRQATYTTARLGSF---RVLTNKAIEANDGRPLPLVQKAFIGL 416 ++G Y+G+ +RQA RLG + + L ++ +PL +G Sbjct: 163 VRDKGFSGLYRGVLPVSMRQAANQAVRLGCYNKIKTLIQDYTDSPKDKPLSSGLTFLVGA 222 Query: 417 TAGAIGACVGSPADLALIRMQA-DSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGP 593 +G + P D RMQ+ DST Y + + I +EG+ WKGA P Sbjct: 223 FSGIVTVYSTMPLDTVKTRMQSLDST-------KYSSTMNCFATIFKEEGLKTFWKGATP 275 Query: 594 TVVR 605 + R Sbjct: 276 RLGR 279
>ADT1_SOLTU (P25083) ADP,ATP carrier protein, mitochondrial precursor (ADP/ATP| translocase) (Adenine nucleotide translocator) (ANT) Length = 386 Score = 43.9 bits (102), Expect = 4e-04 Identities = 48/197 (24%), Positives = 80/197 (40%), Gaps = 16/197 (8%) Frame = +3 Query: 105 GVWKTIKP-FVNGGASGMLATCVIQPIDMIKVKI--------QLGE---GSAAQVAKTMY 248 G WK +GGA+G + + +D + ++ + GE V K Sbjct: 186 GYWKWFAGNLASGGAAGASSLFFVYSLDYARTRLANDRKASKKGGERQFNGLVDVYKKTL 245 Query: 249 ANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGA 428 ++G+ Y+G + + Y G + L + N L F G Sbjct: 246 KSDGIAGLYRGFNISCVGIIVYRGLYFGMYDSLKPVLLTGN------LQDSFFASFGLGW 299 Query: 429 I---GACVGS-PADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPT 596 + GA + S P D RM S + YK++ A +I +EG +L+KGAG Sbjct: 300 LITNGAGLASYPIDTVRRRMMMTS----GEAVKYKSSLDAFSQIVKNEGPKSLFKGAGAN 355 Query: 597 VVRAMSLNMGMLASYDQ 647 ++RA++ G+LA YD+ Sbjct: 356 ILRAVA-GAGVLAGYDK 371
>YG5F_YEAST (P53320) Putative mitochondrial carrier YGR257C| Length = 366 Score = 43.5 bits (101), Expect = 6e-04 Identities = 44/202 (21%), Positives = 78/202 (38%), Gaps = 22/202 (10%) Frame = +3 Query: 111 WKTIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTMYANEGLG-------- 266 + T+ P G + + A I P++++K K+Q S+ M + L Sbjct: 156 YPTLNPLFCGAIARVFAATSIAPLELVKTKLQSIPRSSKSTKTWMMVKDLLNETRQEMKM 215 Query: 267 -----SFYKGLSAGLLRQATYTTARLGSFRV------LTNKAIEANDGRPLPLVQKAFIG 413 + +KGL L R ++ S+ + L + + D + + G Sbjct: 216 VGPSRALFKGLEITLWRDVPFSAIYWSSYELCKERLWLDSTRFASKDANWVHFINSFASG 275 Query: 414 LTAGAIGACVGSPADLALIRMQA---DSTLPAAQRRHYKNAFHALYRITADEGVLALWKG 584 +G I A P D+ R Q +++ P R +N F L I EG+ AL+ G Sbjct: 276 CISGMIAAICTHPFDVGKTRWQISMMNNSDPKGGNRS-RNMFKFLETIWRTEGLAALYTG 334 Query: 585 AGPTVVRAMSLNMGMLASYDQS 650 V++ M++SY+ S Sbjct: 335 LAARVIKIRPSCAIMISSYEIS 356 Score = 30.8 bits (68), Expect = 3.7 Identities = 12/43 (27%), Positives = 23/43 (53%) Frame = +3 Query: 516 YKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYD 644 + A +I + EG+ +LW+G T++ A+ NM + Y+ Sbjct: 102 FNGTLEAFTKIASVEGITSLWRGISLTLLMAIPANMVYFSGYE 144
>ANT1_ASHGO (Q75A82) Peroxisomal adenine nucleotide transporter 1| Length = 340 Score = 43.5 bits (101), Expect = 6e-04 Identities = 41/195 (21%), Positives = 77/195 (39%), Gaps = 12/195 (6%) Frame = +3 Query: 84 QQAAAPTGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQL-----GEGSAAQVAKTMY 248 +QA + T + V G + + + PI+++ + Q G VA+ ++ Sbjct: 124 KQARGGDARFSTPEELVLGIVAAATSQLFVNPINVVATRQQTRGQAAGAADMRTVAREVH 183 Query: 249 ANEGLGSFYKGLSAGL-------LRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAF 407 A G F+ GL L + ATY R F + + L Q Sbjct: 184 AENGWRGFWAGLKVSLVLTVNPSITYATYERLREALFPTPAAASHLVDSAALLSPGQNFV 243 Query: 408 IGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGA 587 +G+ + + + P +A +Q + +++ L+ + + EG L+LWKG Sbjct: 244 MGVLSKIVSTVLTQPLIIAKASLQRSGSC-------FQDFHQVLHHLYSTEGPLSLWKGL 296 Query: 588 GPTVVRAMSLNMGML 632 GP + + + L G+L Sbjct: 297 GPQITKGV-LVQGLL 310 Score = 30.8 bits (68), Expect = 3.7 Identities = 36/153 (23%), Positives = 57/153 (37%), Gaps = 9/153 (5%) Frame = +3 Query: 171 IQPIDMIKVKIQLGEGSAAQVAKTMYANEGLGSFYKGLS----AGLLRQAT----YTTAR 326 I+PI + + A + +Y EG+ Y+GL AG ++ + YT R Sbjct: 58 IKPIALRSPQAAEQYKGALDALQRIYGAEGVAGLYRGLGSSTVAGFIQSFSYFFWYTLVR 117 Query: 327 LGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQA-DSTLPAA 503 FR+ + +A P LV +G+ A A +P ++ R Q AA Sbjct: 118 KHYFRLKQARGGDARFSTPEELV----LGIVAAATSQLFVNPINVVATRQQTRGQAAGAA 173 Query: 504 QRRHYKNAFHALYRITADEGVLALWKGAGPTVV 602 R H A+ G W G ++V Sbjct: 174 DMRTVAREVH------AENGWRGFWAGLKVSLV 200
>ADT2_MOUSE (P51881) ADP/ATP translocase 2 (Adenine nucleotide translocator 2)| (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) Length = 297 Score = 43.5 bits (101), Expect = 6e-04 Identities = 41/180 (22%), Positives = 68/180 (37%), Gaps = 9/180 (5%) Frame = +3 Query: 135 NGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAK---------TMYANEGLGSFYKGLS 287 +GGA+G + C + P+D + ++ G A + +Y ++G+ Y+G + Sbjct: 118 SGGAAGATSLCFVYPLDFARTRLAADVGKAGAEREFKGLGDCLVKIYKSDGIKGLYQGFN 177 Query: 288 AGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 467 + Y A G + T K + D + + I + A+ P D Sbjct: 178 VSVQGIIIYRAAYFGIYD--TAKGM-LPDPKNTHIFISWMIAQSVTAVAGLTSYPFDTVR 234 Query: 468 IRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYDQ 647 RM S Y +I DEG A +KGA V+R M +L YD+ Sbjct: 235 RRMMMQSGRKGTDIM-YTGTLDCWRKIARDEGSKAFFKGAWSNVLRGMG-GAFVLVLYDE 292 Score = 42.0 bits (97), Expect = 0.002 Identities = 40/188 (21%), Positives = 71/188 (37%), Gaps = 14/188 (7%) Frame = +3 Query: 123 KPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTMY-----------ANEGLGS 269 K F+ GG + ++ + PI+ +K+ +Q+ S A Y +G+ S Sbjct: 9 KDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLS 68 Query: 270 FYKGLSAGLLR---QATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGAC 440 F++G A ++R A ++ + ++ G AGA C Sbjct: 69 FWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWRYFAGNLASGGAAGATSLC 128 Query: 441 VGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLN 620 P D A R+ AD A+ R +K L +I +G+ L++G +V + Sbjct: 129 FVYPLDFARTRLAADVGKAGAE-REFKGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYR 187 Query: 621 MGMLASYD 644 YD Sbjct: 188 AAYFGIYD 195 Score = 31.6 bits (70), Expect = 2.2 Identities = 21/84 (25%), Positives = 36/84 (42%), Gaps = 8/84 (9%) Frame = +3 Query: 420 AGAIGACVGSPADLALIRMQADSTLPAAQR-----RHYKNAFHALYRITADEGVLALWKG 584 AG + A + A + R++ + A + + YK + RI ++GVL+ W+G Sbjct: 13 AGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLSFWRG 72 Query: 585 AGPTVVR---AMSLNMGMLASYDQ 647 V+R +LN Y Q Sbjct: 73 NLANVIRYFPTQALNFAFKDKYKQ 96
>ADT2_ANOGA (Q7PQV7) ADP,ATP carrier protein 2 (ADP/ATP translocase 2) (Adenine| nucleotide translocator 2) (ANT 2) Length = 300 Score = 43.1 bits (100), Expect = 7e-04 Identities = 43/180 (23%), Positives = 69/180 (38%), Gaps = 9/180 (5%) Frame = +3 Query: 135 NGGASGMLATCVIQPIDMIKVKI--QLGEGSAAQVAK-------TMYANEGLGSFYKGLS 287 +GG +G + C + P+D + ++ +G+G+ A+ K ++ +GL Y+G Sbjct: 121 SGGMAGATSLCFVYPLDFARTRLAADVGKGAEAREFKGLGDCISKIFKTDGLVGLYRGFG 180 Query: 288 AGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 467 + Y A G + T + + N + P I + V P D Sbjct: 181 VSVQGIIIYRAAYFGFYD--TARGMLPNP-KTTPWYVSWAIAQCVTTVAGIVSYPFDTVR 237 Query: 468 IRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYDQ 647 RM S A YK H I EG A +KGA V+R +L YD+ Sbjct: 238 RRMMMQSG-RAKSEIVYKGTLHCWATIAKQEGTGAFFKGAFSNVLRGTG-GAFVLVLYDE 295
>ADT2_RAT (Q09073) ADP/ATP translocase 2 (Adenine nucleotide translocator 2)| (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) Length = 297 Score = 43.1 bits (100), Expect = 7e-04 Identities = 41/180 (22%), Positives = 68/180 (37%), Gaps = 9/180 (5%) Frame = +3 Query: 135 NGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAK---------TMYANEGLGSFYKGLS 287 +GGA+G + C + P+D + ++ G A + +Y ++G+ Y+G + Sbjct: 118 SGGAAGATSLCFVYPLDFARTRLAADVGKAGAEREFKGLGDCLVKIYKSDGIKGLYQGFN 177 Query: 288 AGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 467 + Y A G + T K + D + + I + A+ P D Sbjct: 178 VSVQGIIIYRAAYFGIYD--TAKGM-LPDPKNTHIFISWMIAQSVTAVAGLTSYPFDTVR 234 Query: 468 IRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYDQ 647 RM S Y +I DEG A +KGA V+R M +L YD+ Sbjct: 235 RRMMMQSGRKGTDIM-YTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMG-GAFVLVLYDE 292 Score = 42.0 bits (97), Expect = 0.002 Identities = 40/188 (21%), Positives = 71/188 (37%), Gaps = 14/188 (7%) Frame = +3 Query: 123 KPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTMY-----------ANEGLGS 269 K F+ GG + ++ + PI+ +K+ +Q+ S A Y +G+ S Sbjct: 9 KDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLS 68 Query: 270 FYKGLSAGLLR---QATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGAC 440 F++G A ++R A ++ + ++ G AGA C Sbjct: 69 FWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWRYFAGNLASGGAAGATSLC 128 Query: 441 VGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLN 620 P D A R+ AD A+ R +K L +I +G+ L++G +V + Sbjct: 129 FVYPLDFARTRLAADVGKAGAE-REFKGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYR 187 Query: 621 MGMLASYD 644 YD Sbjct: 188 AAYFGIYD 195 Score = 31.6 bits (70), Expect = 2.2 Identities = 21/84 (25%), Positives = 36/84 (42%), Gaps = 8/84 (9%) Frame = +3 Query: 420 AGAIGACVGSPADLALIRMQADSTLPAAQR-----RHYKNAFHALYRITADEGVLALWKG 584 AG + A + A + R++ + A + + YK + RI ++GVL+ W+G Sbjct: 13 AGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLSFWRG 72 Query: 585 AGPTVVR---AMSLNMGMLASYDQ 647 V+R +LN Y Q Sbjct: 73 NLANVIRYFPTQALNFAFKDKYKQ 96
>ADT_ORYSA (P31691) ADP,ATP carrier protein, mitochondrial precursor (ADP/ATP| translocase) (Adenine nucleotide translocator) (ANT) Length = 382 Score = 42.7 bits (99), Expect = 0.001 Identities = 45/197 (22%), Positives = 79/197 (40%), Gaps = 16/197 (8%) Frame = +3 Query: 105 GVWKTIKP-FVNGGASGMLATCVIQPIDMIKVKIQLGEGSA-----------AQVAKTMY 248 G WK +GGA+G + + +D + ++ +A V + Sbjct: 182 GYWKWFGGNLASGGAAGASSLFFVYSLDYARTRLANDAKAAKGGGERQFNGLVDVYRKTL 241 Query: 249 ANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGA 428 ++G+ Y+G + + Y G + L + + L F G Sbjct: 242 KSDGIAGLYRGFNISCVGIIVYRGLYFGMYDSLKPVVLTGS------LQDNFFASFALGW 295 Query: 429 I---GACVGS-PADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPT 596 + GA + S P D RM S + YK++ A +I +EG +L+KGAG Sbjct: 296 LITNGAGLASYPIDTVRRRMMMTS----GEAVKYKSSMDAFSQILKNEGAKSLFKGAGAN 351 Query: 597 VVRAMSLNMGMLASYDQ 647 ++RA++ G+L+ YDQ Sbjct: 352 ILRAIA-GAGVLSGYDQ 367
>PM34_MOUSE (O70579) Peroxisomal membrane protein PMP34 (34 kDa peroxisomal| membrane protein) (Solute carrier family 25 member 17) Length = 307 Score = 42.7 bits (99), Expect = 0.001 Identities = 41/172 (23%), Positives = 75/172 (43%), Gaps = 15/172 (8%) Frame = +3 Query: 132 VNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQ----VAKTMYANEGLGSFYKG----LS 287 V G + A V P+D ++++Q+ E ++ V + EGL + Y+G +S Sbjct: 14 VAGAVGSVTAMTVFFPLDTARLRLQVDEKRKSKTTHAVLLEIIKEEGLLAPYRGWFPVIS 73 Query: 288 AGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 467 + Y S + + K ++ G+ L +G AG + + +P + Sbjct: 74 SLCCSNFVYFYT-FNSLKAVWVKGQRSSTGKDL------VVGFVAGVVNVLLTTPLWVVN 126 Query: 468 IRMQADSTLPAAQRRH-------YKNAFHALYRITADEGVLALWKGAGPTVV 602 R++ L A+ R+ YK A ++I DEG+LALW G P+++ Sbjct: 127 TRLK----LQGAKFRNEDIIPTNYKGIIDAFHQIIRDEGILALWNGTFPSLL 174
>ADT1_MAIZE (P04709) ADP,ATP carrier protein 1, mitochondrial precursor| (ADP/ATP translocase 1) (Adenine nucleotide translocator 1) (ANT 1) Length = 387 Score = 42.7 bits (99), Expect = 0.001 Identities = 45/197 (22%), Positives = 78/197 (39%), Gaps = 16/197 (8%) Frame = +3 Query: 105 GVWKTIKP-FVNGGASGMLATCVIQPIDMIKVKIQLGEGSA-----------AQVAKTMY 248 G WK +GGA+G + + +D + ++ +A V + Sbjct: 187 GYWKWFAGNLASGGAAGASSLFFVYSLDYARTRLANDAKAAKGGGERQFNGLVDVYRKTL 246 Query: 249 ANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGA 428 ++G+ Y+G + + Y G + + + N L F G Sbjct: 247 KSDGIAGLYRGFNISCVGIIVYRGLYFGLYDSIKPVVLTGN------LQDNFFASFALGW 300 Query: 429 I---GACVGS-PADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPT 596 + GA + S P D RM S + YK++ A +I EG +L+KGAG Sbjct: 301 LITNGAGLASYPIDTVRRRMMMTS----GEAVKYKSSLDAFQQILKKEGPKSLFKGAGAN 356 Query: 597 VVRAMSLNMGMLASYDQ 647 ++RA++ G+L+ YDQ Sbjct: 357 ILRAIA-GAGVLSGYDQ 372
>ADT2_SOLTU (P27081) ADP,ATP carrier protein, mitochondrial precursor (ADP/ATP| translocase) (Adenine nucleotide translocator) (ANT) (Fragment) Length = 386 Score = 42.7 bits (99), Expect = 0.001 Identities = 44/198 (22%), Positives = 84/198 (42%), Gaps = 17/198 (8%) Frame = +3 Query: 105 GVWKTIKP-FVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQ------------VAKTM 245 G WK +GG +G + + +D + ++ +A + V + Sbjct: 185 GYWKWFAGNLASGGGAGASSLLFVYSLDYARTRLANDAKAAKKGGGGRQFDGLVDVYRKT 244 Query: 246 YANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAG 425 ++G+ Y+G + + Y G + L +P+ L K A Sbjct: 245 LKSDGVAGLYRGFNISCVGIIVYRGLYFGMYDSL----------KPVLLTGKMEDSFFAS 294 Query: 426 -AIGACVGSPADLA---LIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGP 593 A+G + + A LA + ++ + + + YK++F A +I +EG +L+KGAG Sbjct: 295 FALGWLITNGAGLASYPIDTVRRRMMMTSGEAVKYKSSFDAFNQILKNEGPKSLFKGAGA 354 Query: 594 TVVRAMSLNMGMLASYDQ 647 V+RA++ G+LA YD+ Sbjct: 355 NVLRAVA-GAGVLAGYDK 371
>MFRN1_HUMAN (Q9NYZ2) Mitoferrin-1 (Mitochondrial iron transporter 1) (Solute| carrier family 25 member 37) (Mitochondria solute carrier protein) Length = 347 Score = 42.4 bits (98), Expect = 0.001 Identities = 34/148 (22%), Positives = 64/148 (43%), Gaps = 9/148 (6%) Frame = +3 Query: 132 VNGGASGMLATCVIQPIDMIKVKIQLGEG---SAAQVAKTMYANEGLGSFYKGLSAGLLR 302 + G + +L V+ P +++K ++Q+ SA +T++ EGLG+FY+ + L Sbjct: 148 IAGSMATLLHDAVMNPAEVVKQRLQMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTM 207 Query: 303 QATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADL--ALIRM 476 + + ++ L + N R G AGA+ A +P D+ L+ Sbjct: 208 NIPFQSIHFITYEFLQE---QVNPHRTYNPQSHIISGGLAGALAAAATTPLDVCKTLLNT 264 Query: 477 QADSTLPAA----QRRHYKNAFHALYRI 548 Q + L A + NAF +Y++ Sbjct: 265 QENVALSLANISGRLSGMANAFRTVYQL 292
>MPCP_MOUSE (Q8VEM8) Phosphate carrier protein, mitochondrial precursor (PTP)| (Solute carrier family 25 member 3) Length = 357 Score = 42.4 bits (98), Expect = 0.001 Identities = 49/215 (22%), Positives = 93/215 (43%), Gaps = 6/215 (2%) Frame = +3 Query: 30 SSPSPARSRRKEMADAKQQQAAAPTGVWKTIKPFVNGG--ASGMLATCVIQPIDMIKVKI 203 S P+P R R + +A A ++ + G K GG + G+ T V+ P+D++K ++ Sbjct: 31 SPPAPPR-RSRHLAAAAVEEYSCEFGSMKYYALCGFGGVLSCGLTHTAVV-PLDLVKCRM 88 Query: 204 QLGEGSAAQVAKTM---YANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEAND 374 Q+ + +G+ KG + L+ + + G + V KA+ +N Sbjct: 89 QVDPQKYKGIFNGFSITLKEDGVRGLAKGWAPTLIGYSMQGLCKFGFYEVF--KALYSNI 146 Query: 375 -GRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRIT 551 G + + + L + A AD+AL M+A Q + A+ ++ Sbjct: 147 LGEENTYLWRTSLYLASSASAEFF---ADIALAPMEAAKVRIQTQPGYANTLREAVPKMY 203 Query: 552 ADEGVLALWKGAGPTVVRAMSLNMGMLASYDQSVE 656 +EG+ A +KG P +R + M A ++++VE Sbjct: 204 KEEGLNAFYKGVAPLWMRQIPYTMMKFACFERTVE 238
>GHC2_RAT (Q505J6) Mitochondrial glutamate carrier 2 (GC-2) (Glutamate/H(+)| symporter 2) (Solute carrier family 25 member 18) Length = 315 Score = 42.0 bits (97), Expect = 0.002 Identities = 31/124 (25%), Positives = 48/124 (38%) Frame = +3 Query: 219 SAAQVAKTMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQ 398 SA +A + +GL Y+GL A LLR ++ F L + G+ Sbjct: 165 SATLIAWELLRTQGLSGLYRGLGATLLRDIPFSIIYFPLFANLNQLGVSELTGK-ASFTH 223 Query: 399 KAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALW 578 G AG++ A +P D+ R+Q + Y+ ++ EG A Sbjct: 224 SFVAGCAAGSVSAVAVTPLDVLKTRIQ--TLKKGLGEDTYRGVTDCARKLWTQEGAAAFM 281 Query: 579 KGAG 590 KGAG Sbjct: 282 KGAG 285 Score = 41.6 bits (96), Expect = 0.002 Identities = 40/183 (21%), Positives = 72/183 (39%), Gaps = 25/183 (13%) Frame = +3 Query: 132 VNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQ------VAKTMYANEGLGSFYKGLSAG 293 +NGG +G++ + PID+ K ++Q +G + KT A EG Y+G + Sbjct: 13 INGGIAGLVGVTCVFPIDLAKTRLQNQQGKDVYKGMTDCLVKTARA-EGFLGMYRGAAVN 71 Query: 294 LLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIR 473 L +L + L + + DG L + G AG + P ++ I+ Sbjct: 72 LTLVTPEKAIKLAANDFL--RQLLMQDGTQRNLKMEMLAGCGAGICQVVITCPMEMLKIQ 129 Query: 474 MQADSTLPAAQR---------RHYKNAFHALYR----------ITADEGVLALWKGAGPT 596 +Q L Q+ R Y + +R + +G+ L++G G T Sbjct: 130 LQDAGRLAVCQQASASATPTSRPYSTGSTSTHRRPSATLIAWELLRTQGLSGLYRGLGAT 189 Query: 597 VVR 605 ++R Sbjct: 190 LLR 192
>MPCP_RAT (P16036) Phosphate carrier protein, mitochondrial precursor (PTP)| (Solute carrier family 25 member 3) Length = 356 Score = 42.0 bits (97), Expect = 0.002 Identities = 50/215 (23%), Positives = 91/215 (42%), Gaps = 6/215 (2%) Frame = +3 Query: 30 SSPSPARSRRKEMADAKQQQAAAPTGVWKTIKPFVNGG--ASGMLATCVIQPIDMIKVKI 203 S P P R R + +A A + + G K GG + G+ T V+ P+D++K ++ Sbjct: 30 SPPGPPR-RSRHLAAAAVEGYSCEFGSMKYYALCGFGGVLSCGLTHTAVV-PLDLVKCRM 87 Query: 204 QLGEGSAAQVAKTM---YANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEAND 374 Q+ + +G+ KG + L+ + + G + V KA+ +N Sbjct: 88 QVDPQKYKGIFNGFSITLKEDGVRGLAKGWAPTLIGYSMQGLCKFGFYEVF--KALYSNI 145 Query: 375 -GRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRIT 551 G + + + L A A AD+AL M+A Q + A+ ++ Sbjct: 146 LGEENTYLWRTSLYLAASASAEFF---ADIALAPMEAAKVRIQTQPGYANTLREAVPKMY 202 Query: 552 ADEGVLALWKGAGPTVVRAMSLNMGMLASYDQSVE 656 +EG+ A +KG P +R + M A ++++VE Sbjct: 203 KEEGLNAFYKGVAPVWMRQIPYTMMKFACFERTVE 237
>ORNT2_HUMAN (Q9BXI2) Mitochondrial ornithine transporter 2 (Solute carrier| family 25 member 2) Length = 301 Score = 42.0 bits (97), Expect = 0.002 Identities = 42/165 (25%), Positives = 62/165 (37%), Gaps = 9/165 (5%) Frame = +3 Query: 138 GGASGMLATCVIQPIDMIKVKIQ----LGEGSAAQVAKTMYANEGLGSFYKGLSAGLLRQ 305 G A G QP D IKVK+Q L +G KT YA GL FYKG L+ Sbjct: 16 GAAGGTACVLTGQPFDTIKVKMQTFPDLYKGLTDCFLKT-YAQVGLRGFYKGTGPALMAY 74 Query: 306 ATYTTARL---GSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRM 476 + G + K + L +Q A G A A A P +L R+ Sbjct: 75 VAENSVLFMCYGFCQQFVRKVAGMDKQAKLSDLQTAAAGSFASAFAALALCPTELVKCRL 134 Query: 477 QA--DSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVR 605 Q + + + + + + I +G L + G T+++ Sbjct: 135 QTMYEMEMSGKIAKSHNTIWSVVKGILKKDGPLGFYHGLSSTLLQ 179 Score = 40.4 bits (93), Expect = 0.005 Identities = 42/188 (22%), Positives = 78/188 (41%), Gaps = 17/188 (9%) Frame = +3 Query: 138 GGASGMLATCVIQPIDMIKVKIQL------------GEGSAAQVAKTMYANEGLGSFYKG 281 G + A + P +++K ++Q + V K + +G FY G Sbjct: 113 GSFASAFAALALCPTELVKCRLQTMYEMEMSGKIAKSHNTIWSVVKGILKKDGPLGFYHG 172 Query: 282 LSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGAC---VGSP 452 LS+ LL++ G + + +++ A+ GR + + L+ G G C + P Sbjct: 173 LSSTLLQEGPGYFFFFGGYEL--SRSFFAS-GRSKDELGPVHLMLSGGVAGICLWLIVFP 229 Query: 453 ADLALIRMQADSTLPAAQRRHYKNA--FHALYRITADEGVLALWKGAGPTVVRAMSLNMG 626 D R+Q S + K A L + +EG++AL+ G T++RA+ N Sbjct: 230 VDCIKSRIQVLSM-------YGKQAGFIGTLLSVVRNEGIVALYSGLKATMIRAIPANGA 282 Query: 627 MLASYDQS 650 + +Y+ S Sbjct: 283 LFVAYEYS 290 Score = 35.4 bits (80), Expect = 0.15 Identities = 27/85 (31%), Positives = 38/85 (44%), Gaps = 4/85 (4%) Frame = +3 Query: 399 KAFIGLTAGAIG--ACV--GSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGV 566 +A I LTAGA G ACV G P D ++MQ L YK + A G+ Sbjct: 8 QAAIDLTAGAAGGTACVLTGQPFDTIKVKMQTFPDL-------YKGLTDCFLKTYAQVGL 60 Query: 567 LALWKGAGPTVVRAMSLNMGMLASY 641 +KG GP ++ ++ N + Y Sbjct: 61 RGFYKGTGPALMAYVAENSVLFMCY 85 Score = 34.7 bits (78), Expect = 0.26 Identities = 20/62 (32%), Positives = 35/62 (56%), Gaps = 5/62 (8%) Frame = +3 Query: 132 VNGGASGMLATCVIQPIDMIKVKIQLGE--GSAAQVAKTMYA---NEGLGSFYKGLSAGL 296 ++GG +G+ ++ P+D IK +IQ+ G A T+ + NEG+ + Y GL A + Sbjct: 214 LSGGVAGICLWLIVFPVDCIKSRIQVLSMYGKQAGFIGTLLSVVRNEGIVALYSGLKATM 273 Query: 297 LR 302 +R Sbjct: 274 IR 275
>ADT_SCHPO (Q09188) ADP,ATP carrier protein (ADP/ATP translocase) (Adenine| nucleotide translocator) (ANT) Length = 322 Score = 42.0 bits (97), Expect = 0.002 Identities = 44/190 (23%), Positives = 79/190 (41%), Gaps = 19/190 (10%) Frame = +3 Query: 135 NGGASGMLATCVIQPIDMIKVKIQLGEGSAAQ-----------VAKTMYANEGLGSFYKG 281 +GGA+G + + +D + ++ SA + V + Y ++GL Y+G Sbjct: 138 SGGAAGAASLLFVYSLDYARTRLANDAKSAKKGGERQFNGLVDVYRKTYRSDGLRGLYRG 197 Query: 282 LSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLV-------QKAFIGLTAGAIGAC 440 ++ Y G + L +P+ LV +F+ A G+ Sbjct: 198 FGPSVVGIVVYRGLYFGMYDTL----------KPVVLVGPLEGNFLASFLLGWAVTTGSG 247 Query: 441 VGS-PADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSL 617 V S P D RM + + + Y ++F +I A EG + +KGAG ++R ++ Sbjct: 248 VASYPLDTIRRRMM----MTSGEAVKYSSSFECGRQILAKEGARSFFKGAGANILRGVA- 302 Query: 618 NMGMLASYDQ 647 G+L+ YDQ Sbjct: 303 GAGVLSIYDQ 312 Score = 35.0 bits (79), Expect = 0.20 Identities = 43/174 (24%), Positives = 67/174 (38%), Gaps = 16/174 (9%) Frame = +3 Query: 129 FVNGGASGMLATCVIQPIDMIKVKIQLGE------------GSAAQVAKTMYANEGLGSF 272 F+ GG S ++ PI+ +K+ IQ + + K A EG+ S Sbjct: 31 FMMGGVSAAVSKTAAAPIERVKLLIQNQDEMIRAGRLSHRYKGIGECFKRTAAEEGVISL 90 Query: 273 YKGLSAGLLRQATYTTARLGSFRVLTNKAI---EANDGRPLPLVQKAFIGLTAGAIGACV 443 ++G +A +LR T A +F+ K + DG G AGA Sbjct: 91 WRGNTANVLRYFP-TQALNFAFKDKFKKMFGYKKERDGYAKWFAGNLASGGAAGAASLLF 149 Query: 444 GSPADLALIRMQADSTLPAAQRRHYKNAFHALYRIT-ADEGVLALWKGAGPTVV 602 D A R+ D+ N +YR T +G+ L++G GP+VV Sbjct: 150 VYSLDYARTRLANDAKSAKKGGERQFNGLVDVYRKTYRSDGLRGLYRGFGPSVV 203 Score = 32.7 bits (73), Expect = 0.99 Identities = 19/68 (27%), Positives = 33/68 (48%), Gaps = 2/68 (2%) Frame = +3 Query: 408 IGLTAGAIGACVGSPAD-LALIRMQADSTLPAAQRRH-YKNAFHALYRITADEGVLALWK 581 +G + A+ +P + + L+ D + A + H YK R A+EGV++LW+ Sbjct: 33 MGGVSAAVSKTAAAPIERVKLLIQNQDEMIRAGRLSHRYKGIGECFKRTAAEEGVISLWR 92 Query: 582 GAGPTVVR 605 G V+R Sbjct: 93 GNTANVLR 100
>ADT1_GOSHI (O22342) ADP,ATP carrier protein 1, mitochondrial precursor| (ADP/ATP translocase 1) (Adenine nucleotide translocator 1) (ANT 1) Length = 386 Score = 41.6 bits (96), Expect = 0.002 Identities = 45/200 (22%), Positives = 81/200 (40%), Gaps = 19/200 (9%) Frame = +3 Query: 105 GVWKTIKP-FVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQ-----------VAKTMY 248 G WK +GGA+G + + +D + ++ +A + V + Sbjct: 186 GYWKWFAGNLASGGAAGASSLLFVYSLDYARTRLANDAKAAKKGGERQFNGLVDVYRKTL 245 Query: 249 ANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIG----- 413 ++G+ Y+G + + Y G + L + + +Q +F Sbjct: 246 KSDGIAGLYRGFNISCVGIIVYRGLYFGMYDSLKPVLLTGS-------MQDSFFASFVLG 298 Query: 414 --LTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGA 587 +T GA A P D RM S + YK++ A +I +EG +L+KGA Sbjct: 299 WLITNGA--ALASYPIDTVRRRMMMTS----GKAVKYKSSLDAFSQILKNEGGKSLFKGA 352 Query: 588 GPTVVRAMSLNMGMLASYDQ 647 G ++RA++ G+LA YD+ Sbjct: 353 GSNILRAIA-GAGVLAGYDK 371 Score = 29.6 bits (65), Expect = 8.3 Identities = 43/182 (23%), Positives = 67/182 (36%), Gaps = 16/182 (8%) Frame = +3 Query: 87 QAAAPTGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQ-----LGEGSAAQ------- 230 QA A G F+ GG S ++ PI+ +K+ IQ + G ++ Sbjct: 76 QAPAEKGFSSFAIDFLMGGVSAAVSKTAAAPIERVKLLIQNQDEMIKSGRLSEPYKGIGD 135 Query: 231 VAKTMYANEGLGSFYKGLSAGLLR---QATYTTARLGSFRVLTNKAIEANDGRPLPLVQK 401 K +EG GS ++G +A ++R A F+ L N + DG Sbjct: 136 CFKRTIKDEGFGSLWRGNTANVIRYFPTQALNFAFKDYFKRLFNFK-KDRDGYWKWFAGN 194 Query: 402 AFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRIT-ADEGVLALW 578 G AGA D A R+ D+ N +YR T +G+ L+ Sbjct: 195 LASGGAAGASSLLFVYSLDYARTRLANDAKAAKKGGERQFNGLVDVYRKTLKSDGIAGLY 254 Query: 579 KG 584 +G Sbjct: 255 RG 256
>ADT_CHLKE (P31692) ADP,ATP carrier protein (ADP/ATP translocase) (Adenine| nucleotide translocator) (ANT) Length = 339 Score = 41.6 bits (96), Expect = 0.002 Identities = 41/176 (23%), Positives = 79/176 (44%), Gaps = 16/176 (9%) Frame = +3 Query: 120 IKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGS----AAQVAK---------TMYANEG 260 +K + GG +G ++ + PI+ +K+ +Q + + + QV + + + +G Sbjct: 42 VKDLLAGGTAGAISKTAVAPIERVKLLLQTQDSNPMIKSGQVPRYTGIVNCFVRVSSEQG 101 Query: 261 LGSFYKGLSAGLLR---QATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAI 431 + SF++G A ++R + A + + L K D +V A GL AGA Sbjct: 102 VASFWRGNLANVVRYFPTQAFNFAFKDTIKGLFPKYSPKTDFWRFFVVNLASGGL-AGAG 160 Query: 432 GACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTV 599 + P D A R+ AD + + + R + L ++ G +AL++G G +V Sbjct: 161 SLLIVYPLDFARTRLAAD--VGSGKSREFTGLVDCLSKVVKRGGPMALYQGFGVSV 214 Score = 38.1 bits (87), Expect = 0.023 Identities = 21/78 (26%), Positives = 37/78 (47%), Gaps = 3/78 (3%) Frame = +3 Query: 381 PLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLP---AAQRRHYKNAFHALYRIT 551 P+ V+ G TAGAI +P + + +Q + P + Q Y + R++ Sbjct: 38 PMAFVKDLLAGGTAGAISKTAVAPIERVKLLLQTQDSNPMIKSGQVPRYTGIVNCFVRVS 97 Query: 552 ADEGVLALWKGAGPTVVR 605 +++GV + W+G VVR Sbjct: 98 SEQGVASFWRGNLANVVR 115 Score = 34.7 bits (78), Expect = 0.26 Identities = 39/191 (20%), Positives = 66/191 (34%), Gaps = 9/191 (4%) Frame = +3 Query: 102 TGVWKT-IKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKT--------MYAN 254 T W+ + +GG +G + ++ P+D + ++ GS T + Sbjct: 141 TDFWRFFVVNLASGGLAGAGSLLIVYPLDFARTRLAADVGSGKSREFTGLVDCLSKVVKR 200 Query: 255 EGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIG 434 G + Y+G + Y A G + T K + D R K + A Sbjct: 201 GGPMALYQGFGVSVQGIIVYRGAYFGLYD--TAKGVLFKDERTANFFAKWAVAQAVTAGA 258 Query: 435 ACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMS 614 + P D R+ S R Y ++ EG+ A +KGA V+R Sbjct: 259 GVLSYPFDTVRRRLMMQS----GGERQYNGTIDCWRKVAQQEGMKAFFKGAWSNVLRGAG 314 Query: 615 LNMGMLASYDQ 647 +L YD+ Sbjct: 315 -GAFVLVLYDE 324
>ADT1_ANOGA (Q27238) ADP,ATP carrier protein 1 (ADP/ATP translocase 1) (Adenine| nucleotide translocator 1) (ANT 1) Length = 301 Score = 41.6 bits (96), Expect = 0.002 Identities = 44/180 (24%), Positives = 68/180 (37%), Gaps = 9/180 (5%) Frame = +3 Query: 135 NGGASGMLATCVIQPIDMIKVKIQLGEGSAA---------QVAKTMYANEGLGSFYKGLS 287 +GGA+G + C + P+D + ++ G A K ++G+ Y+G + Sbjct: 121 SGGAAGATSLCFVYPLDFARTRLGADVGRGAGEREFNGLLDCLKKTVKSDGIIGLYRGFN 180 Query: 288 AGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 467 + Y A G F T K + + V A + A G + P D Sbjct: 181 VSVQGIIIYRAAYFGCFD--TAKGMLPDPKNTSIFVSWAIAQVVTTASG-IISYPFDTVR 237 Query: 468 IRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYDQ 647 RM S A YKN +I EG A +KGA V+R + +L YD+ Sbjct: 238 RRMMMQSG-RAKSEVMYKNTLDCWVKIGKQEGSGAFFKGAFSNVLRGTGGAL-VLVFYDE 295 Score = 30.8 bits (68), Expect = 3.7 Identities = 23/84 (27%), Positives = 35/84 (41%), Gaps = 8/84 (9%) Frame = +3 Query: 420 AGAIGACVGSPADLALIRMQADSTLPAAQR-----RHYKNAFHALYRITADEGVLALWKG 584 AG I A V A + R++ + AA + + YK RI ++G+ A W+G Sbjct: 16 AGGISAAVSKTAVAPIERVKLLLQVQAASKQIAVDKQYKGIVDCFVRIPKEQGIGAFWRG 75 Query: 585 AGPTVVR---AMSLNMGMLASYDQ 647 V+R +LN Y Q Sbjct: 76 NLANVIRYFPTQALNFAFKDVYKQ 99
>GHC2_HUMAN (Q9H1K4) Mitochondrial glutamate carrier 2 (GC-2) (Glutamate/H(+)| symporter 2) (Solute carrier family 25 member 18) Length = 315 Score = 41.6 bits (96), Expect = 0.002 Identities = 40/183 (21%), Positives = 72/183 (39%), Gaps = 25/183 (13%) Frame = +3 Query: 132 VNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQ------VAKTMYANEGLGSFYKGLSAG 293 +NGG +G++ + PID+ K ++Q G A + KT A EG Y+G + Sbjct: 13 INGGVAGLVGVTCVFPIDLAKTRLQNQHGKAMYKGMIDCLMKTARA-EGFFGMYRGAAVN 71 Query: 294 LLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIR 473 L +L + +E DG L + G AG V P ++ I+ Sbjct: 72 LTLVTPEKAIKLAANDFFRRLLME--DGMQRNLKMEMLAGCGAGMCQVVVTCPMEMLKIQ 129 Query: 474 M----------QADSTLPAAQRRH---------YKNAFHALYRITADEGVLALWKGAGPT 596 + Q ++ P+ R + +A + + +G+ L++G G T Sbjct: 130 LQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAGLYRGLGAT 189 Query: 597 VVR 605 ++R Sbjct: 190 LLR 192 Score = 40.0 bits (92), Expect = 0.006 Identities = 33/124 (26%), Positives = 47/124 (37%) Frame = +3 Query: 219 SAAQVAKTMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQ 398 SA +A + +GL Y+GL A LLR ++ F L N G+ Sbjct: 165 SATLIAWELLRTQGLAGLYRGLGATLLRDIPFSIIYFPLFANLNNLGFNELAGK-ASFAH 223 Query: 399 KAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALW 578 G AG+I A +P D+ R+Q + Y ++ EG A Sbjct: 224 SFVSGCVAGSIAAVAVTPLDVLKTRIQ--TLKKGLGEDMYSGITDCARKLWIQEGPSAFM 281 Query: 579 KGAG 590 KGAG Sbjct: 282 KGAG 285
>MFRN2_MOUSE (Q8R0Z5) Mitoferrin-2 (Mitochondrial iron transporter 2) (Solute| carrier family 25 member 28) (Mitochondrial RNA splicing protein 3/4 homolog) (MRS3/4) Length = 364 Score = 41.2 bits (95), Expect = 0.003 Identities = 38/169 (22%), Positives = 71/169 (42%), Gaps = 12/169 (7%) Frame = +3 Query: 132 VNGGASGMLATCV----IQPIDMIKVKIQLGEGSAAQVA---KTMYANEGLGSFYKGLSA 290 + GA+G +AT + + P +++K ++Q+ +V + ++ NEG G+FY+ + Sbjct: 171 IANGAAGCVATLLHDAAMNPAEVVKQRMQMYNSPYHRVTDCVRAVWQNEGAGAFYRSYTT 230 Query: 291 GLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADL--A 464 L + ++ L N R G AGA+ A +P D+ Sbjct: 231 QLTMNVPFQAIHFMTYEFLQE---HFNPQRRYNPSSHVLCGACAGAVAAAATTPLDVCKT 287 Query: 465 LIRMQADSTLPAAQRRH---YKNAFHALYRITADEGVLALWKGAGPTVV 602 L+ Q L + H +AF +Y++ GV A ++G V+ Sbjct: 288 LLNTQESLALNSNITGHITGMASAFRTVYQV---GGVTAYFRGVQARVI 333 Score = 38.5 bits (88), Expect = 0.018 Identities = 26/79 (32%), Positives = 36/79 (45%) Frame = +3 Query: 411 GLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAG 590 G AG + CV P D RMQ+ PAA+ Y+N AL+RI EG+ +G Sbjct: 79 GAVAGILEHCVMYPIDCVKTRMQSLQPDPAAR---YRNVLEALWRIMRTEGLWRPMRGLN 135 Query: 591 PTVVRAMSLNMGMLASYDQ 647 T A + A Y++ Sbjct: 136 VTATGAGPAHALYFACYEK 154 Score = 30.0 bits (66), Expect = 6.4 Identities = 24/72 (33%), Positives = 34/72 (47%), Gaps = 7/72 (9%) Frame = +3 Query: 93 AAPTGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQ-LGEGSAAQVAKTMYA------ 251 A P G T V G +G+L CV+ PID +K ++Q L AA+ + A Sbjct: 65 ALPAGATVTTH-MVAGAVAGILEHCVMYPIDCVKTRMQSLQPDPAARYRNVLEALWRIMR 123 Query: 252 NEGLGSFYKGLS 287 EGL +GL+ Sbjct: 124 TEGLWRPMRGLN 135
>PM34_HUMAN (O43808) Peroxisomal membrane protein PMP34 (34 kDa peroxisomal| membrane protein) (Solute carrier family 25 member 17) Length = 307 Score = 41.2 bits (95), Expect = 0.003 Identities = 41/172 (23%), Positives = 73/172 (42%), Gaps = 15/172 (8%) Frame = +3 Query: 132 VNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQ----VAKTMYANEGLGSFYKG----LS 287 V G + A V P+D ++++Q+ E ++ V + EGL + Y+G +S Sbjct: 14 VAGAVGSVTAMTVFFPLDTARLRLQVDEKRKSKTTHMVLLEIIKEEGLLAPYRGWFPVIS 73 Query: 288 AGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLAL 467 + Y S + L K + G+ L +G AG + + +P + Sbjct: 74 SLCCSNFVYFYT-FNSLKALWVKGQHSTTGKDL------VVGFVAGVVNVLLTTPLWVVN 126 Query: 468 IRMQADSTLPAAQRRH-------YKNAFHALYRITADEGVLALWKGAGPTVV 602 R++ L A+ R+ YK A ++I DEG+ ALW G P+++ Sbjct: 127 TRLK----LQGAKFRNEDIVPTNYKGIIDAFHQIIRDEGISALWNGTFPSLL 174
>MFRN2_HUMAN (Q96A46) Mitoferrin-2 (Mitochondrial iron transporter 2) (Solute| carrier family 25 member 28) (Mitochondrial RNA splicing protein 3/4 homolog) (MRS3/4) (hMRS3/4) Length = 364 Score = 40.8 bits (94), Expect = 0.004 Identities = 38/169 (22%), Positives = 71/169 (42%), Gaps = 12/169 (7%) Frame = +3 Query: 132 VNGGASGMLATCV----IQPIDMIKVKIQLGEGSAAQVA---KTMYANEGLGSFYKGLSA 290 + GA+G +AT + + P +++K ++Q+ +V + ++ NEG G+FY+ + Sbjct: 171 IANGAAGCVATLLHDAAMNPAEVVKQRMQMYNSPYHRVTDCVRAVWQNEGAGAFYRSYTT 230 Query: 291 GLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADL--A 464 L + ++ L N R G AGA+ A +P D+ Sbjct: 231 QLTMNVPFQAIHFMTYEFLQE---HFNPQRRYNPSSHVLSGACAGAVAAAATTPLDVCKT 287 Query: 465 LIRMQADSTLPAAQRRH---YKNAFHALYRITADEGVLALWKGAGPTVV 602 L+ Q L + H +AF +Y++ GV A ++G V+ Sbjct: 288 LLNTQESLALNSHITGHITGMASAFRTVYQV---GGVTAYFRGVQARVI 333 Score = 38.5 bits (88), Expect = 0.018 Identities = 26/79 (32%), Positives = 36/79 (45%) Frame = +3 Query: 411 GLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAG 590 G AG + CV P D RMQ+ PAA+ Y+N AL+RI EG+ +G Sbjct: 79 GAVAGILEHCVMYPIDCVKTRMQSLQPDPAAR---YRNVLEALWRIIRTEGLWRPMRGLN 135 Query: 591 PTVVRAMSLNMGMLASYDQ 647 T A + A Y++ Sbjct: 136 VTATGAGPAHALYFACYEK 154 Score = 30.8 bits (68), Expect = 3.7 Identities = 25/79 (31%), Positives = 36/79 (45%), Gaps = 7/79 (8%) Frame = +3 Query: 72 DAKQQQAAAPTGVWKTIKPFVNGGASGMLATCVIQPIDMIKVKIQ-LGEGSAAQVAKTMY 248 D+ A P G T V G +G+L CV+ PID +K ++Q L AA+ + Sbjct: 58 DSGPDYEALPAGATVTTH-MVAGAVAGILEHCVMYPIDCVKTRMQSLQPDPAARYRNVLE 116 Query: 249 A------NEGLGSFYKGLS 287 A EGL +GL+ Sbjct: 117 ALWRIIRTEGLWRPMRGLN 135
>ADT2_MAIZE (P12857) ADP,ATP carrier protein 2, mitochondrial precursor| (ADP/ATP translocase 2) (Adenine nucleotide translocator 2) (ANT 2) Length = 387 Score = 40.8 bits (94), Expect = 0.004 Identities = 44/197 (22%), Positives = 78/197 (39%), Gaps = 16/197 (8%) Frame = +3 Query: 105 GVWKTIKP-FVNGGASGMLATCVIQPIDMIKVKIQLGEGSA-----------AQVAKTMY 248 G WK +GGA+G + + +D + ++ +A V + Sbjct: 187 GYWKWFAGNLASGGAAGASSLFFVYSLDYARTRLANDAKAAKGGGDRQFNGLVDVYRKTL 246 Query: 249 ANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGA 428 ++G+ Y+G + + Y G + + + + L F G Sbjct: 247 KSDGIAGLYRGFNISCVGIIVYRGLYFGLYDSIKPVVLTGS------LQDNFFASFALGW 300 Query: 429 I---GACVGS-PADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPT 596 + GA + S P D RM S + YK++ A +I EG +L+KGAG Sbjct: 301 LITNGAGLASYPIDTVRRRMMMTS----GEAVKYKSSLDAFQQILKKEGPKSLFKGAGAN 356 Query: 597 VVRAMSLNMGMLASYDQ 647 ++RA++ G+L+ YDQ Sbjct: 357 ILRAIA-GAGVLSGYDQ 372
>ADT2_WHEAT (Q41630) ADP,ATP carrier protein 2, mitochondrial precursor| (ADP/ATP translocase 2) (Adenine nucleotide translocator 2) (ANT 2) Length = 331 Score = 40.8 bits (94), Expect = 0.004 Identities = 47/197 (23%), Positives = 79/197 (40%), Gaps = 16/197 (8%) Frame = +3 Query: 105 GVWKTIKP-FVNGGASGMLATCVIQPIDMIKVKI------QLGEGSA-----AQVAKTMY 248 G WK +GGA+G + + +D + ++ G G V + Sbjct: 131 GYWKWFGGNLASGGAAGASSLFFVYSLDYGRTRLANDAKASKGGGDRQFNGLVDVYRKTL 190 Query: 249 ANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGA 428 ++G+ Y+G + + Y G + L + L +F G Sbjct: 191 KSDGIAGLYRGFNISCVGIIVYRGLYFGLYDSLKPVLLTGT------LQVCSFASFALGW 244 Query: 429 I---GACVGS-PADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPT 596 + GA + S P D RM S + YK++ A +I A EG +L+KGAG Sbjct: 245 LITNGAGLASYPIDTVRRRMMMTS----GEAVKYKSSLDAFQQIPAKEGAKSLFKGAGAN 300 Query: 597 VVRAMSLNMGMLASYDQ 647 ++RA++ G+L+ YDQ Sbjct: 301 ILRAIA-GAGVLSGYDQ 316
>MPCP_YEAST (P23641) Mitochondrial phosphate carrier protein (Phosphate| transport protein) (PTP) (mPic 1) (Mitochondrial import receptor) (p32) Length = 311 Score = 40.4 bits (93), Expect = 0.005 Identities = 42/182 (23%), Positives = 76/182 (41%), Gaps = 6/182 (3%) Frame = +3 Query: 129 FVNGGASGMLAT-CVIQPIDMIKVKIQL-----GEGSAAQVAKTMYANEGLGSFYKGLSA 290 F GA G +T + PID++K +IQL +G K + A EG G+ G Sbjct: 20 FALAGAIGCGSTHSSMVPIDVVKTRIQLEPTVYNKGMVGSF-KQIIAGEGAGALLTGFGP 78 Query: 291 GLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALI 470 LL + + G + V I+ N G K + + + A+ + AD+AL Sbjct: 79 TLLGYSIQGAFKFGGYEVFKKFFID-NLGYDTASRYKNSVYMGSAAMAEFL---ADIALC 134 Query: 471 RMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYDQS 650 ++A +Q + RI +EG+ + + G P + + + N+ ++++ Sbjct: 135 PLEATRIRLVSQPQFANGLVGGFSRILKEEGIGSFYSGFTPILFKQIPYNIAKFLVFERA 194 Query: 651 VE 656 E Sbjct: 195 SE 196 Score = 37.0 bits (84), Expect = 0.052 Identities = 32/127 (25%), Positives = 52/127 (40%), Gaps = 13/127 (10%) Frame = +3 Query: 156 LATCVIQPIDMIKVKI----QLGEGSAAQVAKTMYANEGLGSFYKGLSAGLLRQATYTTA 323 LA + P++ ++++ Q G ++ + EG+GSFY G + L +Q Y A Sbjct: 128 LADIALCPLEATRIRLVSQPQFANGLVGGFSRIL-KEEGIGSFYSGFTPILFKQIPYNIA 186 Query: 324 RLGSFRVLTNKAIEANDGRPLP---------LVQKAFIGLTAGAIGACVGSPADLALIRM 476 + ++ +A E G P + GLTAG A V PAD L ++ Sbjct: 187 KF----LVFERASEFYYGFAGPKEKLSSTSTTLLNLLSGLTAGLAAAIVSQPADTLLSKV 242 Query: 477 QADSTLP 497 P Sbjct: 243 NKTKKAP 249
>MFRN1_BRARE (Q287T7) Mitoferrin-1 (Mitochondrial iron transporter 1) (Solute| carrier family 25 member 37) (Protein frascati) Length = 332 Score = 40.4 bits (93), Expect = 0.005 Identities = 39/166 (23%), Positives = 66/166 (39%), Gaps = 6/166 (3%) Frame = +3 Query: 132 VNGGASGMLATCVIQPIDMIKVKIQLGEG---SAAQVAKTMYANEGLGSFYKGLSAGLLR 302 V G + +L V+ P +++K ++Q+ S + EGL +FY+ S L Sbjct: 136 VAGSVATVLHDAVMNPAEVVKQRMQMYNSPYRSLYDCVLMVSRKEGLAAFYRSYSTQLTM 195 Query: 303 QATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADL--ALIRM 476 + ++ + RP + G AGA+ A V +P D+ L+ Sbjct: 196 NIPFQAVHFITYEFMQEHFNPHRQYRPETHI---ISGAAAGAVSAAVTTPLDVCKTLLNT 252 Query: 477 QADSTLPAAQ-RRHYKNAFHALYRITADEGVLALWKGAGPTVVRAM 611 Q + L +A H +AL + GV A +KG V+ M Sbjct: 253 QENVALSSAHVSGHLSGMVNALRTVYRLGGVPAFFKGIQARVIYQM 298 Score = 35.0 bits (79), Expect = 0.20 Identities = 26/79 (32%), Positives = 37/79 (46%) Frame = +3 Query: 411 GLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAG 590 G AG + V P D RMQ+ P AQ Y++ + AL RI EG+L +G Sbjct: 40 GAVAGILEHTVMYPVDSVKTRMQSLQPDPKAQ---YRSVYGALKRIVRTEGLLRPLRGLN 96 Query: 591 PTVVRAMSLNMGMLASYDQ 647 TV+ A + A Y++ Sbjct: 97 ITVLGAGPAHALYFACYER 115 Score = 32.0 bits (71), Expect = 1.7 Identities = 19/75 (25%), Positives = 35/75 (46%), Gaps = 13/75 (17%) Frame = +3 Query: 132 VNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVA-------------KTMYANEGLGSF 272 ++G A+G ++ V P+D+ K + E A A +T+Y G+ +F Sbjct: 227 ISGAAAGAVSAAVTTPLDVCKTLLNTQENVALSSAHVSGHLSGMVNALRTVYRLGGVPAF 286 Query: 273 YKGLSAGLLRQATYT 317 +KG+ A ++ Q T Sbjct: 287 FKGIQARVIYQMPST 301
>ADT1_WHEAT (Q41629) ADP,ATP carrier protein 1, mitochondrial precursor| (ADP/ATP translocase 1) (Adenine nucleotide translocator 1) (ANT 1) Length = 331 Score = 40.4 bits (93), Expect = 0.005 Identities = 43/197 (21%), Positives = 82/197 (41%), Gaps = 16/197 (8%) Frame = +3 Query: 105 GVWKTIKP-FVNGGASGMLATCVIQPIDMIKVKI------QLGEGSA-----AQVAKTMY 248 G WK +GGA+G + + +D + ++ G G V + Sbjct: 131 GYWKWFGGNLASGGAAGASSLFFVYSLDYARTRLANDAKASKGGGERQFNGLVDVYRKTL 190 Query: 249 ANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAG- 425 ++G+ Y+G + + Y G + L +P+ L + A Sbjct: 191 KSDGIAGLYRGFNISCVGIIVYRGLYFGLYDSL----------KPVLLTGTLQVCFFASF 240 Query: 426 AIGACVGSPADLA---LIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPT 596 A+G + + A LA + ++ + + + YK++ A +I EG +L+KGAG Sbjct: 241 ALGWLITNGAGLASYPIDTVRRRMMMTSGEAVKYKSSLDAFQQILKKEGAKSLFKGAGAN 300 Query: 597 VVRAMSLNMGMLASYDQ 647 ++RA++ G+L+ YDQ Sbjct: 301 ILRAIA-GAGVLSGYDQ 316
>ADT1_ARATH (P31167) ADP,ATP carrier protein 1, mitochondrial precursor| (ADP/ATP translocase 1) (Adenine nucleotide translocator 1) (ANT 1) Length = 381 Score = 39.7 bits (91), Expect = 0.008 Identities = 43/198 (21%), Positives = 79/198 (39%), Gaps = 17/198 (8%) Frame = +3 Query: 105 GVWKTIKP-FVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQ------------VAKTM 245 G WK +GGA+G + + +D + ++ +A + V + Sbjct: 180 GYWKWFAGNLASGGAAGASSLLFVYSLDYARTRLANDAKAAKKGGGGRQFDGLVDVYRKT 239 Query: 246 YANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAG 425 +G+ Y+G + + Y G + + + + L F G Sbjct: 240 LKTDGIAGLYRGFNISCVGIIVYRGLYFGLYDSVKPVLLTGD------LQDSFFASFALG 293 Query: 426 AI---GACVGS-PADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGP 593 + GA + S P D RM S + YK++ A +I +EG +L+KGAG Sbjct: 294 WVITNGAGLASYPIDTVRRRMMMTS----GEAVKYKSSLDAFKQILKNEGAKSLFKGAGA 349 Query: 594 TVVRAMSLNMGMLASYDQ 647 ++RA++ G+L+ YD+ Sbjct: 350 NILRAVA-GAGVLSGYDK 366
>ANT1_YEAST (Q06497) Peroxisomal adenine nucleotide transporter 1| Length = 328 Score = 39.7 bits (91), Expect = 0.008 Identities = 43/183 (23%), Positives = 81/183 (44%), Gaps = 8/183 (4%) Frame = +3 Query: 117 TIKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAA----QVAKTMYA--NEGLGSFYK 278 TI+ V G A+ ++ P+ ++ + Q + + V K +Y N + +F+K Sbjct: 124 TIEELVLGVAAASISQLFTSPMAVVATRQQTVHSAESAKFTNVIKDIYRENNGDITAFWK 183 Query: 279 GLSAGLLRQATYTTARLGSFRVLTNKAIE--ANDGRPLPLVQKAFIGLTAGAIGACVGSP 452 GL GL + SF+ L +ND L VQ +G+ + I V P Sbjct: 184 GLRTGLALTIN-PSITYASFQRLKEVFFHDHSNDAGSLSAVQNFILGVLSKMISTLVTQP 242 Query: 453 ADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGML 632 +A +Q+ ++ ++ A LY+ +EG+ +LWKG P + + + + G+L Sbjct: 243 LIVAKAMLQS----AGSKFTTFQEALLYLYK---NEGLKSLWKGVLPQLTKGV-IVQGLL 294 Query: 633 ASY 641 ++ Sbjct: 295 FAF 297 Score = 30.0 bits (66), Expect = 6.4 Identities = 20/85 (23%), Positives = 36/85 (42%), Gaps = 9/85 (10%) Frame = +3 Query: 393 VQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQ---------RRHYKNAFHALYR 545 ++ A G A A+ P DL+ +Q+ + +++ R YKN + Sbjct: 4 LESALTGAVASAMANIAVYPLDLSKTIIQSQVSPSSSEDSNEGKVLPNRRYKNVVDCMIN 63 Query: 546 ITADEGVLALWKGAGPTVVRAMSLN 620 I ++G+L L++G T V N Sbjct: 64 IFKEKGILGLYQGMTVTTVATFVQN 88
>ADT1_YEAST (P04710) ADP,ATP carrier protein 1 (ADP/ATP translocase 1) (Adenine| nucleotide translocator 1) (ANT 1) Length = 309 Score = 39.3 bits (90), Expect = 0.011 Identities = 43/174 (24%), Positives = 72/174 (41%), Gaps = 16/174 (9%) Frame = +3 Query: 129 FVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVA------------KTMYANEGLGSF 272 F+ GG S +A PI+ +K+ +Q E Q + K +EG+ SF Sbjct: 17 FLMGGVSAAIAKTGAAPIERVKLLMQNQEEMLKQGSLDTRYKGILDCFKRTATHEGIVSF 76 Query: 273 YKGLSAGLLRQATYTTARLGSFRVLTNKAI---EANDGRPLPLVQKAFIGLTAGAIGACV 443 ++G +A +LR T A +F+ + DG F G AG + Sbjct: 77 WRGNTANVLRYFP-TQALNFAFKDKIKSLLSYDRERDGYAKWFAGNLFSGGAAGGLSLLF 135 Query: 444 GSPADLALIRMQADSTLPAAQRRHYKNAFHALYRIT-ADEGVLALWKGAGPTVV 602 D A R+ AD+ + + N +Y+ T +G+L L++G P+V+ Sbjct: 136 VYSLDYARTRLAADARGSKSTSQRQFNGLLDVYKKTLKTDGLLGLYRGFVPSVL 189
>MFRN2_BRARE (Q7T292) Mitoferrin-2 (Mitochondrial iron transporter 2) (Solute| carrier family 25 member 28) Length = 376 Score = 38.1 bits (87), Expect = 0.023 Identities = 26/79 (32%), Positives = 37/79 (46%) Frame = +3 Query: 411 GLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAG 590 G AG + C+ P D RMQ+ PAA+ Y+N AL+RI EG+ +G Sbjct: 84 GAVAGIMEHCLMFPIDCVKTRMQSLQPEPAAR---YRNVMDALWRIMRTEGIWRPIRGLN 140 Query: 591 PTVVRAMSLNMGMLASYDQ 647 T V A + A Y++ Sbjct: 141 ITAVGAGPAHALYFACYER 159
>MFRN_CAEEL (Q23125) Mitoferrin| Length = 312 Score = 38.1 bits (87), Expect = 0.023 Identities = 32/133 (24%), Positives = 57/133 (42%), Gaps = 10/133 (7%) Frame = +3 Query: 141 GASGMLAT----CVIQPIDMIKVKIQLG---EGSAAQVAKTMYANEGLGSFYKGLSAGLL 299 GASG++AT ++ P +++K ++Q+ GS+ + A+ +Y EG+ +FY+ + L Sbjct: 118 GASGVVATLIHDAIMNPAEVVKQRMQMAFSPYGSSLECARCVYNREGVAAFYRSYTTQLA 177 Query: 300 RQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPAD---LALI 470 + S+ + N G AG + A + +P D L Sbjct: 178 MNVPFQAIHFMSYEFWQH---VLNPEHKYDPKSHLIAGGLAGGLAAALTTPMDCVKTVLN 234 Query: 471 RMQADSTLPAAQR 509 QA PA +R Sbjct: 235 TQQAAEADPANRR 247
>MPCP_CHOFU (O61703) Phosphate carrier protein, mitochondrial precursor| (Phosphate transport protein) (PTP) Length = 349 Score = 37.7 bits (86), Expect = 0.031 Identities = 47/193 (24%), Positives = 70/193 (36%), Gaps = 17/193 (8%) Frame = +3 Query: 117 TIKPFVNGGASG---MLATCVIQPIDMIKVKIQLGEGSAAQVAKTMYANEG--LGSFYKG 281 T + FV AS A + P++ KV+IQ G A+ + A +G G++ + Sbjct: 143 TYRTFVYLAASASAEFFADIALSPLEAAKVRIQTMPGVRQHTARRV-AQDGPERGAWARS 201 Query: 282 LSAGLL---RQATYTTARLGSFR---------VLTNKAIEANDGRPLPLVQKAFIGLTAG 425 A + RQ YT + F V+ E + G L + A G AG Sbjct: 202 TRALVPLWGRQIPYTMMKFACFEKTVELLYKHVVPKPRAECSKGEQLVVTFAA--GYIAG 259 Query: 426 AIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVR 605 A V PAD + ++ D T I G +WKG GP ++ Sbjct: 260 VFCAIVSHPADTVVSKLNQDKTATVGS-------------IVGKLGFAGVWKGLGPRIIM 306 Query: 606 AMSLNMGMLASYD 644 +L YD Sbjct: 307 IGTLTALQWFIYD 319
>MRS4_YEAST (P23500) Mitochondrial RNA-splicing protein MRS4| Length = 304 Score = 37.4 bits (85), Expect = 0.040 Identities = 34/164 (20%), Positives = 61/164 (37%), Gaps = 3/164 (1%) Frame = +3 Query: 120 IKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAA-QVAKTMYANEGLGSFYKGLSAGL 296 +K ++G + + A ++ P D +K ++QL V K +Y NEG +FY L Sbjct: 121 MKTALSGTIATIAADALMNPFDTVKQRLQLDTNLRVWNVTKQIYQNEGFAAFYYSYPTTL 180 Query: 297 LRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPADL--ALI 470 + + + N PL G +GA A + +P D ++ Sbjct: 181 AMNIPFAAFNFMIYESASKFFNPQNSYNPL---IHCLCGGISGATCAALTTPLDCIKTVL 237 Query: 471 RMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVV 602 +++ T+ + A I G W+G P +V Sbjct: 238 QVRGSETVSIEIMKDANTFGRASRAILEVHGWKGFWRGLKPRIV 281
>YIA6_YEAST (P40556) Putative mitochondrial carrier YIL006W| Length = 373 Score = 37.0 bits (84), Expect = 0.052 Identities = 22/77 (28%), Positives = 35/77 (45%), Gaps = 7/77 (9%) Frame = +3 Query: 147 SGMLATCVIQPIDMIKVKIQLGEGSAAQVA-------KTMYANEGLGSFYKGLSAGLLRQ 305 S M+A+ V P ++++ ++QL + K YA EGL FY G + L+R Sbjct: 288 SKMIASAVTYPHEILRTRMQLKSDIPDSIQRRLFPLIKATYAQEGLKGFYSGFTTNLVRT 347 Query: 306 ATYTTARLGSFRVLTNK 356 + L SF N+ Sbjct: 348 IPASAITLVSFEYFRNR 364 Score = 36.2 bits (82), Expect = 0.089 Identities = 21/67 (31%), Positives = 29/67 (43%) Frame = +3 Query: 402 AFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWK 581 A G AG + P D+A R+QA + +Y+ L I DEG L+K Sbjct: 81 ALSGAFAGFLSGVAVCPLDVAKTRLQAQGLQTRFENPYYRGIMGTLSTIVRDEGPRGLYK 140 Query: 582 GAGPTVV 602 G P V+ Sbjct: 141 GLVPIVL 147
>RIM2_YEAST (P38127) Mitochondrial carrier protein RIM2| Length = 377 Score = 36.6 bits (83), Expect = 0.068 Identities = 42/191 (21%), Positives = 76/191 (39%), Gaps = 20/191 (10%) Frame = +3 Query: 147 SGMLATCVIQPIDMIKVKIQLGEGSAAQVA---------KTMYANEGLGSFYKGLSA--- 290 +G PI +IK ++QL + V K++ NEG YKGLSA Sbjct: 185 AGWATATATNPIWLIKTRVQLDKAGKTSVRQYKNSWDCLKSVIRNEGFTGLYKGLSASYL 244 Query: 291 ----GLLRQATY-TTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGA-IGACVGSP 452 G+L+ Y RL R + +A + K + + A + V S Sbjct: 245 GSVEGILQWLLYEQMKRLIKERSIEKFGYQAEGTKSTSEKVKEWCQRSGSAGLAKFVASI 304 Query: 453 ADL--ALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMG 626 A ++R + T +R Y + I +EG+ +++ G P ++R + ++ Sbjct: 305 ATYPHEVVRTRLRQTPKENGKRKYTGLVQSFKVIIKEEGLFSMYSGLTPHLMRTVPNSII 364 Query: 627 MLASYDQSVEL 659 M +++ + L Sbjct: 365 MFGTWEIVIRL 375 Score = 32.3 bits (72), Expect = 1.3 Identities = 27/103 (26%), Positives = 41/103 (39%), Gaps = 29/103 (28%) Frame = +3 Query: 399 KAFIGLTAGAIGACVGS----PADLALIRMQADSTLPAAQRR------------------ 512 K ++ AG IG G+ P DL R+Q+D L A + + Sbjct: 51 KPWVHFVAGGIGGMAGAVVTCPFDLVKTRLQSDIFLKAYKSQAVNISKGSTRPKSINYVI 110 Query: 513 ----HYKNAFHALYRITADEGVLALWKGAGPT---VVRAMSLN 620 H+K + + EG +L+KG GP V+ A S+N Sbjct: 111 QAGTHFKETLGIIGNVYKQEGFRSLFKGLGPNLVGVIPARSIN 153
>YE08_SCHPO (O13805) Putative mitochondrial carrier C17H9.08| Length = 326 Score = 35.0 bits (79), Expect = 0.20 Identities = 29/129 (22%), Positives = 51/129 (39%), Gaps = 10/129 (7%) Frame = +3 Query: 120 IKPFVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQVA----------KTMYANEGLGS 269 +K + GG +G +A V+ P+D +K+ Q S A K +Y GL Sbjct: 18 VKSGIAGGTAGCVAKSVVAPLDRVKILYQTNHASYRGYAYSRHGLYKAIKHIYHVYGLHG 77 Query: 270 FYKGLSAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGS 449 Y+G +A L R Y + ++ + + + D ++ G AG Sbjct: 78 LYQGHTATLYRVFPYAGIKFVAYEQV--RRVLIRDPEHETHARRFLSGSLAGTCSVFFTY 135 Query: 450 PADLALIRM 476 P +L +R+ Sbjct: 136 PLELIRVRL 144
>FLX1_YEAST (P40464) Mitochondrial FAD carrier protein FLX1| Length = 311 Score = 34.3 bits (77), Expect = 0.34 Identities = 17/44 (38%), Positives = 27/44 (61%) Frame = +3 Query: 387 PLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHY 518 PL ++ GL+AG++ V P DL +R+Q +T +AQ+ HY Sbjct: 8 PLQKEVISGLSAGSVTTLVVHPLDLLKVRLQLSAT--SAQKAHY 49 Score = 32.3 bits (72), Expect = 1.3 Identities = 40/172 (23%), Positives = 65/172 (37%), Gaps = 14/172 (8%) Frame = +3 Query: 138 GGASGMLATCVIQPIDMIKVKIQLGEGSAAQVAKTMY-------ANEGLGSFYKGL---- 284 G +SG++ + PI +IK +I A +MY +G +KGL Sbjct: 132 GASSGLMTAILTNPIWVIKTRIMSTSKGAQGAYTSMYNGVQQLLRTDGFQGLWKGLVPAL 191 Query: 285 ---SAGLLRQATYTTARLGSFRVLTNKAIEANDGRPLPLVQKAFIGLTAGAIGACVGSPA 455 S G L A Y T + R + +G + L I +T+ V Sbjct: 192 FGVSQGALYFAVYDTLKQRKLR------RKRENGLDIHLTNLETIEITSLGKMVSVTLVY 245 Query: 456 DLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAGPTVVRAM 611 L++ S Q+ F + I A++G + L+KG +VRA+ Sbjct: 246 PFQLLKSNLQSFRANEQK---FRLFPLIKLIIANDGFVGLYKGLSANLVRAI 294
>YQ51_CAEEL (Q09461) Putative mitochondrial carrier C16C10.1| Length = 360 Score = 33.9 bits (76), Expect = 0.44 Identities = 13/44 (29%), Positives = 24/44 (54%) Frame = +3 Query: 513 HYKNAFHALYRITADEGVLALWKGAGPTVVRAMSLNMGMLASYD 644 +++ A+ +I EG+ +LW G PT+V A+ + +YD Sbjct: 105 NFRGTADAIVKIARHEGIRSLWSGLSPTMVMALPATVFYFTTYD 148 Score = 33.5 bits (75), Expect = 0.58 Identities = 33/152 (21%), Positives = 61/152 (40%), Gaps = 9/152 (5%) Frame = +3 Query: 216 GSAAQVAKTMYANEGLGSFYKGLSAGLLRQATYTTARLGSF---------RVLTNKAIEA 368 G+A + K + +EG+ S + GLS ++ T ++ ++ +A Sbjct: 108 GTADAIVK-IARHEGIRSLWSGLSPTMVMALPATVFYFTTYDNLSVWLKKKMCCRRAFSP 166 Query: 369 NDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRI 548 P A G+ A I V SP ++ +MQ+ +R Y H + Sbjct: 167 EKWTPPDWSAAAVAGIVARTIAVTVVSPIEMIRTKMQS-------KRLTYHEIGHLVRSS 219 Query: 549 TADEGVLALWKGAGPTVVRAMSLNMGMLASYD 644 A +G+ + + G PT++R + + A YD Sbjct: 220 MATKGISSFYLGWTPTMLRDIPFSGIYWAGYD 251
>MFN2B_XENLA (Q68F18) Mitoferrin-2B (Mitochondrial iron transporter 2-B) (Solute| carrier family 25 member 28-B) Length = 186 Score = 33.9 bits (76), Expect = 0.44 Identities = 24/79 (30%), Positives = 34/79 (43%) Frame = +3 Query: 411 GLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAG 590 G AG + C+ P D RMQ+ PAA+ Y+N AL +I EG +G Sbjct: 84 GAVAGVMEHCLMYPVDCVKTRMQSLQPDPAAR---YRNVMDALSKIVRTEGFWRPLRGLN 140 Query: 591 PTVVRAMSLNMGMLASYDQ 647 T A + A Y++ Sbjct: 141 VTATGAGPAHALYFACYEK 159
>MFN2A_XENLA (Q6GLJ0) Mitoferrin-2A (Mitochondrial iron transporter 2-A) (Solute| carrier family 25 member 28-A) Length = 186 Score = 33.9 bits (76), Expect = 0.44 Identities = 24/79 (30%), Positives = 34/79 (43%) Frame = +3 Query: 411 GLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYRITADEGVLALWKGAG 590 G AG + C+ P D RMQ+ PAA+ Y+N AL +I EG +G Sbjct: 84 GAVAGVMEHCLMYPVDCVKTRMQSLQPDPAAR---YRNVMDALSKIVRTEGFWRPLRGLN 140 Query: 591 PTVVRAMSLNMGMLASYDQ 647 T A + A Y++ Sbjct: 141 VTATGAGPAHALYFACYEK 159
>YHM1_YEAST (P38988) Putative mitochondrial carrier protein YHM1/SHM1| Length = 300 Score = 33.1 bits (74), Expect = 0.76 Identities = 19/61 (31%), Positives = 31/61 (50%), Gaps = 4/61 (6%) Frame = +3 Query: 129 FVNGGASGMLATCVIQPIDMIKVKIQL----GEGSAAQVAKTMYANEGLGSFYKGLSAGL 296 F++ + V P+D+IK +IQ S ++ K NEG+ +F+KGL+ L Sbjct: 214 FISSIVGACSSLIVSAPLDVIKTRIQNRNFDNPESGLRIVKNTLKNEGVTAFFKGLTPKL 273 Query: 297 L 299 L Sbjct: 274 L 274
>Y051_MYCTU (Q10880) Hypothetical protein Rv0083/MT0090| Length = 640 Score = 33.1 bits (74), Expect = 0.76 Identities = 38/152 (25%), Positives = 65/152 (42%) Frame = +3 Query: 186 MIKVKIQLGEGSAAQVAKTMYANEGLGSFYKGLSAGLLRQATYTTARLGSFRVLTNKAIE 365 +++ I G VA T G+ + GLS + +A G + ++ + Sbjct: 377 LVQSLIHAAPGHDPIVALTTPLAVGVVALATGLSVAAMTKA------FGIGFLARPRSTQ 430 Query: 366 ANDGRPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRRHYKNAFHALYR 545 A R P +A + + AGA +P +A + +A +TLPAAQ + A+ R Sbjct: 431 AEAAREAPASMRAGMAIAAGACLVLAVAPLLVAPMVRRAAATLPAAQAVKF-TGLGAVVR 489 Query: 546 ITADEGVLALWKGAGPTVVRAMSLNMGMLASY 641 + A G +A G V A +L + +LA + Sbjct: 490 LPAMSGSIA--PGVIAAAVLAAALAVAVLARW 519
>YAD8_SCHPO (Q09834) Putative mitochondrial carrier C4G8.08| Length = 271 Score = 32.7 bits (73), Expect = 0.99 Identities = 23/71 (32%), Positives = 34/71 (47%), Gaps = 10/71 (14%) Frame = +3 Query: 114 KTIKPFVNGGA-----SGMLATCVIQ----PIDMIKVKIQLGE-GSAAQVAKTMYANEGL 263 + KP V GA GM A V P+++IK + Q+ + GS T+ +EGL Sbjct: 73 RRFKPSVGEGAILYSICGMTAEVVSSFVWTPLEVIKARTQISQKGSVINTISTLARSEGL 132 Query: 264 GSFYKGLSAGL 296 FY+G G+ Sbjct: 133 KGFYRGYWMGV 143
>SUHB_THEMA (O33832) Inositol-1-monophosphatase (EC 3.1.3.25) (IMPase)| (Inositol-1-phosphatase) (I-1-Pase) Length = 256 Score = 32.0 bits (71), Expect = 1.7 Identities = 23/82 (28%), Positives = 37/82 (45%), Gaps = 2/82 (2%) Frame = +3 Query: 198 KIQLGEGSAAQVAKTMYANEGLGSFYKGLSAGLLRQATY--TTARLGSFRVLTNKAIEAN 371 +++LG A + +T+YA EG G+F+ G + A+ GS+ T K IE Sbjct: 105 EVKLGVVHAPALNETLYAEEGSGAFFNGERIRVSENASLEECVGSTGSYVDFTGKFIERM 164 Query: 372 DGRPLPLVQKAFIGLTAGAIGA 437 + R + L A +GA Sbjct: 165 EKRTRRIRILGSAALNAAYVGA 186
>YHM2_YEAST (Q04013) Mitochondrial DNA replication protein YHM2| Length = 314 Score = 32.0 bits (71), Expect = 1.7 Identities = 31/135 (22%), Positives = 56/135 (41%), Gaps = 8/135 (5%) Frame = +3 Query: 219 SAAQVAKTMYANEGLGSFYKGLSAGLLRQATYTTARLG-------SFRVLTNKAIEANDG 377 S+ V K +Y EG+ KG++A +RQ T +R G R +T K + + Sbjct: 154 SSWSVFKNIYKKEGIRGINKGVNAVAIRQMTNWGSRFGLSRLVEDGIRKITGKTNKDDKL 213 Query: 378 RPLPLVQKAFIGLTAGAIGACVGSPADLALIRMQADSTLPAAQRR-HYKNAFHALYRITA 554 P + + +G G + A P ++ + MQ+ P + F +Y+ Sbjct: 214 NPFEKIGASALG---GGLSAW-NQPIEVIRVEMQSKKEDPNRPKNLTVGKTFKYIYQ--- 266 Query: 555 DEGVLALWKGAGPTV 599 G+ L++G P + Sbjct: 267 SNGLKGLYRGVTPRI 281
>ARGO_PHOLL (Q7N183) Arginine exporter protein argO| Length = 207 Score = 31.2 bits (69), Expect = 2.9 Identities = 14/36 (38%), Positives = 20/36 (55%) Frame = -3 Query: 226 AADPSPNWIFTLIMSMGWMTQVASIPEAPPLTNGFI 119 AA S +W F+L + W + V S P + + NGFI Sbjct: 152 AASASVSWFFSLSLLAAWFSPVLSKPLSQRIINGFI 187
>CG69_MOUSE (Q9D8K8) Mitochondrial carrier protein CGI-69 homolog| Length = 359 Score = 31.2 bits (69), Expect = 2.9 Identities = 14/35 (40%), Positives = 21/35 (60%) Frame = +3 Query: 129 FVNGGASGMLATCVIQPIDMIKVKIQLGEGSAAQV 233 FV GG SGM+A + P D++K + Q+ G+ V Sbjct: 259 FVAGGISGMVAATLTLPFDVVKTQRQMSLGAVEAV 293
>TRX_DROME (P20659) Protein trithorax| Length = 3726 Score = 30.4 bits (67), Expect = 4.9 Identities = 11/26 (42%), Positives = 18/26 (69%) Frame = -2 Query: 377 PIICLNCFVCQNPEGSKTSCRIGSLP 300 P+IC+NC C++ +K S +G+LP Sbjct: 1384 PLICVNCLKCKSCSTTKVSKFVGNLP 1409
>RM19_RECAM (O21264) Mitochondrial 60S ribosomal protein L19| Length = 113 Score = 30.0 bits (66), Expect = 6.4 Identities = 14/47 (29%), Positives = 23/47 (48%) Frame = +3 Query: 198 KIQLGEGSAAQVAKTMYANEGLGSFYKGLSAGLLRQATYTTARLGSF 338 K Q+ G + T Y N+ KG+ G+ ++ YTT +L +F Sbjct: 20 KTQIQSGDILSITTTQYKNKKRKQNLKGICIGIKKRIGYTTIQLRNF 66
>TRX_DROVI (Q24742) Protein trithorax| Length = 3828 Score = 30.0 bits (66), Expect = 6.4 Identities = 11/26 (42%), Positives = 18/26 (69%) Frame = -2 Query: 377 PIICLNCFVCQNPEGSKTSCRIGSLP 300 P+IC+NC C++ +K S +G+LP Sbjct: 1371 PLICVNCLKCKSCATTKVSKFVGNLP 1396 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 88,918,858 Number of Sequences: 219361 Number of extensions: 1871943 Number of successful extensions: 5388 Number of sequences better than 10.0: 177 Number of HSP's better than 10.0 without gapping: 4710 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5098 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 6314008338 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
