ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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更新日：2016年5月1日

Clone Information

BLAST Search Result

Clone Name bags37g11
Clone Library Name barley_pub
No. Definition Score
(bits)		 E
Value
1KPYA_RICCO (Q43117) Pyruvate kinase isozyme A, chloroplast precu... 218 5e-57
2KPYA_TOBAC (Q40545) Pyruvate kinase isozyme A, chloroplast precu... 216 3e-56
3KPYG_RICCO (P55964) Pyruvate kinase isozyme G, chloroplast (EC 2... 132 4e-31
4KPYG_TOBAC (Q40546) Pyruvate kinase isozyme G, chloroplast precu... 128 9e-30
5KPYK_MYCGE (P47458) Pyruvate kinase (EC 2.7.1.40) (PK) 114 2e-25
6KPYK_BACST (Q02499) Pyruvate kinase (EC 2.7.1.40) (PK) 113 2e-25
7KPYK_MYCPN (P78031) Pyruvate kinase (EC 2.7.1.40) (PK) 110 2e-24
8KPYK1_SYNY3 (Q55863) Pyruvate kinase 1 (EC 2.7.1.40) (PK 1) 108 8e-24
9KPYK1_SALTY (P77983) Pyruvate kinase I (EC 2.7.1.40) (PK-1) 107 2e-23
10KPYK1_SALTI (Q8Z6K2) Pyruvate kinase I (EC 2.7.1.40) (PK-1) 107 2e-23
11KPYK_YARLI (P30614) Pyruvate kinase (EC 2.7.1.40) (PK) 107 2e-23
12KPYK1_ECOLI (P0AD61) Pyruvate kinase I (EC 2.7.1.40) (PK-1) 106 3e-23
13KPYK1_ECO57 (P0AD62) Pyruvate kinase I (EC 2.7.1.40) (PK-1) 106 3e-23
14KPYK_CLOAB (O08309) Pyruvate kinase (EC 2.7.1.40) (PK) 105 7e-23
15KPYK_BACPY (P51182) Pyruvate kinase (EC 2.7.1.40) (PK) 105 9e-23
16KPYK_CLOPE (Q46289) Pyruvate kinase (EC 2.7.1.40) (PK) 104 1e-22
17KPYK_BACLI (P51181) Pyruvate kinase (EC 2.7.1.40) (PK) 103 2e-22
18KPYK_LACDE (P34038) Pyruvate kinase (EC 2.7.1.40) (PK) 102 4e-22
19KPYK_KLULA (Q875M9) Pyruvate kinase (EC 2.7.1.40) (PK) 100 2e-21
20KPYK_SCHPO (Q10208) Pyruvate kinase (EC 2.7.1.40) (PK) 100 2e-21
21KPYK_BACSU (P80885) Pyruvate kinase (EC 2.7.1.40) (PK) (Vegetati... 100 2e-21
22KPYK_ASHGO (Q759A9) Pyruvate kinase (EC 2.7.1.40) (PK) 98 1e-20
23KPYK_NEUCR (Q7RVA8) Pyruvate kinase (EC 2.7.1.40) (PK) 97 2e-20
24KPYK_MYCTU (O06134) Pyruvate kinase (EC 2.7.1.40) (PK) 97 3e-20
25KPYK_CHICK (P00548) Pyruvate kinase muscle isozyme (EC 2.7.1.40) 97 3e-20
26KPYK_MYCIT (P94939) Pyruvate kinase (EC 2.7.1.40) (PK) 96 4e-20
27KPYK2_CANGA (Q6FV12) Pyruvate kinase 2 (EC 2.7.1.40) (PK 2) 96 4e-20
28KPYM_PONPY (Q5NVN0) Pyruvate kinase isozyme M1 (EC 2.7.1.40) 96 5e-20
29KPYK_SACKL (Q875S4) Pyruvate kinase (EC 2.7.1.40) (PK) 96 5e-20
30KPYK_DEBHA (Q6BS75) Pyruvate kinase (EC 2.7.1.40) (PK) 96 5e-20
31KPYK_EMENI (P22360) Pyruvate kinase (EC 2.7.1.40) (PK) 96 5e-20
32KPYM_RAT (P11980) Pyruvate kinase isozymes M1/M2 (EC 2.7.1.40) (... 96 7e-20
33KPYM_MOUSE (P52480) Pyruvate kinase isozyme M2 (EC 2.7.1.40) 96 7e-20
34KPYM_HUMAN (P14618) Pyruvate kinase isozymes M1/M2 (EC 2.7.1.40)... 96 7e-20
35KPYK_COREF (Q8FP04) Pyruvate kinase (EC 2.7.1.40) (PK) 96 7e-20
36KPYK_ASPNG (Q12669) Pyruvate kinase (EC 2.7.1.40) (PK) 96 7e-20
37KPYK2_AGRVI (Q44473) Pyruvate kinase (EC 2.7.1.40) (PK) 95 9e-20
38KPYM_RABIT (P11974) Pyruvate kinase isozymes M1/M2 (EC 2.7.1.40)... 95 9e-20
39KPYK_DROME (O62619) Pyruvate kinase (EC 2.7.1.40) (PK) 95 9e-20
40KPYK_METEX (O05118) Pyruvate kinase (EC 2.7.1.40) (PK) 94 2e-19
41KPYM_FELCA (P11979) Pyruvate kinase isozyme M1 (EC 2.7.1.40) (Py... 94 2e-19
42KPYK2_TRYBB (P30616) Pyruvate kinase 2 (EC 2.7.1.40) (PK 2) 94 2e-19
43KPYK1_YEAST (P00549) Pyruvate kinase 1 (EC 2.7.1.40) (PK 1) 94 3e-19
44KPYK_TRIRE (P31865) Pyruvate kinase (EC 2.7.1.40) (PK) 93 3e-19
45KPYK1_TRYBB (P30615) Pyruvate kinase 1 (EC 2.7.1.40) (PK 1) 93 3e-19
46KPYK2_YEAST (P52489) Pyruvate kinase 2 (EC 2.7.1.40) (PK 2) 93 3e-19
47KPYK_LACLA (Q07637) Pyruvate kinase (EC 2.7.1.40) (PK) 93 3e-19
48KPYK_CORGL (Q46078) Pyruvate kinase (EC 2.7.1.40) (PK) 93 4e-19
49KPYK_SACCA (Q875Z9) Pyruvate kinase (EC 2.7.1.40) (PK) 93 4e-19
50KPYK_XENLA (Q92122) Pyruvate kinase muscle isozyme (EC 2.7.1.40)... 92 8e-19
51KPYR_RAT (P12928) Pyruvate kinase isozymes R/L (EC 2.7.1.40) (L-PK) 92 8e-19
52KPYR_HUMAN (P30613) Pyruvate kinase isozymes R/L (EC 2.7.1.40) (... 91 1e-18
53KPYK_AGABI (O94122) Pyruvate kinase (EC 2.7.1.40) (PK) 91 2e-18
54KPYR_CANFA (Q29536) Pyruvate kinase isozyme R (EC 2.7.1.40) (Fra... 91 2e-18
55KPYC_ARATH (O65595) Probable pyruvate kinase, cytosolic isozyme ... 90 3e-18
56KPYK1_CANGA (Q6FIS9) Pyruvate kinase 1 (EC 2.7.1.40) (PK 1) 90 4e-18
57KPYK_LEIME (Q27686) Pyruvate kinase (EC 2.7.1.40) (PK) 90 4e-18
58KPYK2_SYNY3 (P73534) Pyruvate kinase 2 (EC 2.7.1.40) (PK 2) 88 1e-17
59KPYK_TRYBO (Q27788) Pyruvate kinase (EC 2.7.1.40) (PK) 88 1e-17
60KPYK_THEAC (P32044) Pyruvate kinase (EC 2.7.1.40) (PK) 88 1e-17
61KPYC_TOBAC (Q42954) Pyruvate kinase, cytosolic isozyme (EC 2.7.1... 87 3e-17
62KPYR_MOUSE (P53657) Pyruvate kinase isozymes R/L (EC 2.7.1.40) (... 86 4e-17
63KPYK1_AGRVI (P70789) Pyruvate kinase (EC 2.7.1.40) (PK) 86 5e-17
64KPYC_SOYBN (Q42806) Pyruvate kinase, cytosolic isozyme (EC 2.7.1... 84 2e-16
65KPYK_BORBU (O51323) Pyruvate kinase (EC 2.7.1.40) (PK) 84 3e-16
66KPYK_METJA (Q57572) Pyruvate kinase (EC 2.7.1.40) (PK) 83 3e-16
67KPYC_SOLTU (P22200) Pyruvate kinase, cytosolic isozyme (EC 2.7.1... 82 6e-16
68KPYK_EIMTE (O44006) Pyruvate kinase (EC 2.7.1.40) (PK) 82 6e-16
69KPYK_CHLMU (Q9PK61) Pyruvate kinase (EC 2.7.1.40) (PK) 81 2e-15
70KPYK_CHLPN (Q9Z984) Pyruvate kinase (EC 2.7.1.40) (PK) 81 2e-15
71KPYK_CHLTR (P94685) Pyruvate kinase (EC 2.7.1.40) (PK) 80 2e-15
72KPYK_BUCAI (P57404) Pyruvate kinase (EC 2.7.1.40) (PK) 77 3e-14
73KPYK2_SALTY (Q8ZNW0) Pyruvate kinase II (EC 2.7.1.40) (PK-2) 71 2e-12
74KPYK2_ECOLI (P21599) Pyruvate kinase II (EC 2.7.1.40) (PK-2) 70 2e-12
75KPYK_HAEIN (P43924) Pyruvate kinase (EC 2.7.1.40) (PK) 69 7e-12
76KPYK_BUCBP (Q89AI8) Pyruvate kinase (EC 2.7.1.40) (PK) 67 2e-11
77KPYK_BUCAP (Q8K9M3) Pyruvate kinase (EC 2.7.1.40) (PK) 61 1e-09
78KPYK_THELI (Q56301) Pyruvate kinase (EC 2.7.1.40) (PK) (Fragment) 49 1e-05
79KPYK1_PHOLE (O30853) Pyruvate kinase I (EC 2.7.1.40) (PK-1) (Fra... 45 1e-04
80BRIX_METKA (Q8TYC5) Probable brix-domain ribosomal biogenesis pr... 33 0.41
81CILB_KLEPN (P17725) Citrate lyase beta chain (EC 4.1.3.6) (Citra... 31 2.1
82LAG3_CAEEL (Q09260) Protein lag-3 (Abnormal germ line proliferat... 30 4.6
83SCNA_DROME (P35500) Sodium channel protein para (Protein paralytic) 29 6.0
84EXOC2_ARATH (Q8S3U9) Exocyst complex component 2 (Exocyst comple... 29 6.0
85LYS2_CANAL (Q12572) L-aminoadipate-semialdehyde dehydrogenase la... 29 7.8
86LRC48_RAT (Q5XI54) Leucine-rich repeat-containing protein 48 29 7.8
87HUS2_SCHPO (Q09811) ATP-dependent DNA helicase hus2/rqh1 (EC 3.6... 29 7.8 
>KPYA_RICCO (Q43117) Pyruvate kinase isozyme A, chloroplast precursor (EC|
           2.7.1.40)
          Length = 583

 Score =  218 bits (556), Expect = 5e-57
 Identities = 108/166 (65%), Positives = 133/166 (80%), Gaps = 2/166 (1%)
 Frame = +3

Query: 3   ILVGDELVIDGGMATFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLV-ERNFGLPT 179
           + VGDEL++DGGM  FEV EKIG D++C+CTDPGLLLPRA L+FWRDG LV ERN  LPT
Sbjct: 220 VKVGDELLVDGGMVRFEVIEKIGPDVKCRCTDPGLLLPRANLTFWRDGSLVRERNAMLPT 279

Query: 180 LSTKDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLE-HIKIFAKIESLESLK 356
           +S+KDW DI+FGI EGVD IA+SFVK A  I  LK+Y++ RS +  I + AKIES++SLK
Sbjct: 280 ISSKDWLDIDFGIAEGVDFIAISFVKSAEVINHLKSYIAARSRDSDIAVIAKIESIDSLK 339

Query: 357 NLKDIIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           NL++II ASDG MVARGDLG Q+PL Q+P  Q+ IV++C  LNKPV
Sbjct: 340 NLEEIIRASDGAMVARGDLGAQIPLEQVPSAQQNIVQVCRQLNKPV 385
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>KPYA_TOBAC (Q40545) Pyruvate kinase isozyme A, chloroplast precursor (EC|
           2.7.1.40)
          Length = 593

 Score =  216 bits (550), Expect = 3e-56
 Identities = 107/166 (64%), Positives = 132/166 (79%), Gaps = 2/166 (1%)
 Frame = +3

Query: 3   ILVGDELVIDGGMATFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLV-ERNFGLPT 179
           + VGDEL++DGGM  FEV EKIG D++C CTDPGLLLPRA L+FWRDGKLV ERN  LPT
Sbjct: 230 VKVGDELLVDGGMVRFEVIEKIGPDVKCLCTDPGLLLPRANLTFWRDGKLVRERNAMLPT 289

Query: 180 LSTKDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLE-HIKIFAKIESLESLK 356
           +S+KDW DI+FGI EGVD IA+SFVK A  I  LK+Y+  R+ +  I + AKIES++SLK
Sbjct: 290 ISSKDWLDIDFGIAEGVDFIAVSFVKSAEVIKHLKSYIQARARDSDISVIAKIESIDSLK 349

Query: 357 NLKDIIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           NL++II ASDG MVARGDLG Q+PL Q+P  Q+ IV++C  LN+PV
Sbjct: 350 NLEEIIQASDGAMVARGDLGAQIPLEQVPSEQQKIVQICRQLNRPV 395
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>KPYG_RICCO (P55964) Pyruvate kinase isozyme G, chloroplast (EC 2.7.1.40)|
           (Fragment)
          Length = 418

 Score =  132 bits (333), Expect = 4e-31
 Identities = 72/164 (43%), Positives = 101/164 (61%)
 Frame = +3

Query: 3   ILVGDELVIDGGMATFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTL 182
           ++VGD L++DGGM +  V  K    ++C   D G L  R  L+    GK       LP++
Sbjct: 61  VVVGDILLVDGGMMSLAVKSKTSDLVKCVVVDGGELKSRRHLNV--RGKSAR----LPSI 114

Query: 183 STKDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNL 362
           + KDW DI+FG+   VD  A+SFVKDA  +  LK YL R + + I +  KIES +S+ NL
Sbjct: 115 TDKDWGDIKFGVDNQVDFYAVSFVKDAKVVHELKEYLKRCNAD-IHVIVKIESADSIPNL 173

Query: 363 KDIIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
             II ASDG MVARGDLG ++P+ ++P +QE I+  C ++ KPV
Sbjct: 174 HSIISASDGAMVARGDLGAELPIEEVPLLQEDIIRRCHSMQKPV 217
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>KPYG_TOBAC (Q40546) Pyruvate kinase isozyme G, chloroplast precursor (EC|
           2.7.1.40)
          Length = 562

 Score =  128 bits (321), Expect = 9e-30
 Identities = 68/161 (42%), Positives = 99/161 (61%)
 Frame = +3

Query: 12  GDELVIDGGMATFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLSTK 191
           GD L++DGGM +  V  K    ++C+  D G L  R  L+      +  ++  LP+++ K
Sbjct: 207 GDILLVDGGMMSLAVKSKTSDIVKCEVIDGGELKSRRHLN------VRGKSATLPSITEK 260

Query: 192 DWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLKDI 371
           DW DI+FG+   VD  A+SFVKDA  +  LK YL   + + I +  KIES +S+ NL  I
Sbjct: 261 DWDDIKFGVNNQVDFYAVSFVKDAKVVHELKDYLKSCNAD-IHVIVKIESADSIPNLHSI 319

Query: 372 IXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           I ASDG MVARGDLG ++P+ ++P +QE I+  C ++ KPV
Sbjct: 320 ISASDGAMVARGDLGAELPIEEVPLLQEDIIRRCQSMQKPV 360
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>KPYK_MYCGE (P47458) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 508

 Score =  114 bits (284), Expect = 2e-25
 Identities = 61/162 (37%), Positives = 94/162 (58%), Gaps = 2/162 (1%)
 Frame = +3

Query: 9   VGDELVIDGGMATFEVT--EKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTL 182
           +G ++++D G  T  VT  +K    + C   +   +  + +L+      L    + +P L
Sbjct: 146 IGQKILVDDGKLTLVVTRVDKQHNQVICVAKNDHTVFTKKRLN------LPNAQYSIPFL 199

Query: 183 STKDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNL 362
           S KD  DI+FG+++G+D IA SFV    DI  L+ YL  ++   +KI AKIES  +L N+
Sbjct: 200 SEKDLKDIDFGLSQGIDYIAASFVNTVADIKQLRDYLKLKNASGVKIIAKIESNHALNNI 259

Query: 363 KDIIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNK 488
             II ASDG+MVARGDLG+++P  Q+P  Q  +++ C   NK
Sbjct: 260 DKIIKASDGIMVARGDLGLEIPYYQVPYWQRYMIKACRFFNK 301
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>KPYK_BACST (Q02499) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 587

 Score =  113 bits (283), Expect = 2e-25
 Identities = 63/166 (37%), Positives = 103/166 (62%), Gaps = 2/166 (1%)
 Frame = +3

Query: 3   ILVGDELVIDGGMATFEVT--EKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLP 176
           + VG ++++D G+ + EV   +K  G++     + G+L  +  ++    G  V     LP
Sbjct: 116 VSVGAKILLDDGLISLEVNAVDKQAGEIVTTVLNGGVLKNKKGVNV--PGVKVN----LP 169

Query: 177 TLSTKDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLK 356
            ++ KD ADI FGI +G+D IA SFV+ A+D+  ++  L      HI+I AKIE+ E + 
Sbjct: 170 GITEKDRADILFGIRQGIDFIAASFVRRASDVLEIRELLEAHDALHIQIIAKIENEEGVA 229

Query: 357 NLKDIIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           N+ +I+ A+DG+MVARGDLGV++P  ++P IQ+ +++ C  L KPV
Sbjct: 230 NIDEILEAADGLMVARGDLGVEIPAEEVPLIQKLLIKKCNMLGKPV 275
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>KPYK_MYCPN (P78031) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 508

 Score =  110 bits (275), Expect = 2e-24
 Identities = 58/166 (34%), Positives = 96/166 (57%), Gaps = 2/166 (1%)
 Frame = +3

Query: 3   ILVGDELVIDGGMATFEVT--EKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLP 176
           + VG ++++D G  +  V   +     + C   +   +  + +L+      L   ++ +P
Sbjct: 144 VKVGQKILVDDGKLSLVVKRIDTKNNQVICVAQNDHTIFTKKRLN------LPNADYSIP 197

Query: 177 TLSTKDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLK 356
            LS KD  DI+FG+T  +D IA SFV    +I  L+ YL+ ++ +H+K+ AKIES  +L 
Sbjct: 198 FLSAKDLRDIDFGLTHQIDYIAASFVNTTENIKQLRDYLASKNAKHVKLIAKIESNHALN 257

Query: 357 NLKDIIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           N+  II ASDG+MVARGDLG+++P  ++P  Q  +++ C   NK V
Sbjct: 258 NIDGIIKASDGIMVARGDLGLEIPYYKVPYWQRYMIKACRFFNKRV 303
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>KPYK1_SYNY3 (Q55863) Pyruvate kinase 1 (EC 2.7.1.40) (PK 1)|
          Length = 483

 Score =  108 bits (270), Expect = 8e-24
 Identities = 54/155 (34%), Positives = 98/155 (63%)
 Frame = +3

Query: 9   VGDELVIDGGMATFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLST 188
           VG+ +++D G+   +V      ++ C+    G+L  R  ++    G ++     LP+++T
Sbjct: 132 VGERILLDDGLLEMKVVSIQDPEVICEVVTGGILKSRKGVNL--PGLVLT----LPSMTT 185

Query: 189 KDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLKD 368
           KD  D+EFG+++G+D ++LSFV+   DI +LK +L+ R    + + AKIE  +++ NL++
Sbjct: 186 KDKQDLEFGLSQGIDWVSLSFVRKGEDIHTLKQFLAERGHPDLPVIAKIEKPQAIDNLEE 245

Query: 369 IIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELC 473
           I+  S+G+MVARGDLGV+V   ++P +Q+ I+  C
Sbjct: 246 IVAVSNGIMVARGDLGVEVNPEKVPRLQKEIIRRC 280
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>KPYK1_SALTY (P77983) Pyruvate kinase I (EC 2.7.1.40) (PK-1)|
          Length = 470

 Score =  107 bits (267), Expect = 2e-23
 Identities = 58/162 (35%), Positives = 94/162 (58%)
 Frame = +3

Query: 9   VGDELVIDGGMATFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLST 188
           VG+ +++D G+   EVT   G  + CK  + G L     ++      L   +  LP L+ 
Sbjct: 119 VGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVN------LPGVSIALPALAE 172

Query: 189 KDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLKD 368
           KD  D+ FG  +GVD +A SF++  +D+  ++ +L     E+I+I +KIE+ E L N  +
Sbjct: 173 KDKQDLIFGCEQGVDFVAASFIRKRSDVVEIREHLKAHGGENIQIISKIENQEGLNNFDE 232

Query: 369 IIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           I+ ASDG+MVARGDLGV++P+ ++   Q+ ++E C    K V
Sbjct: 233 ILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVV 274
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>KPYK1_SALTI (Q8Z6K2) Pyruvate kinase I (EC 2.7.1.40) (PK-1)|
          Length = 470

 Score =  107 bits (267), Expect = 2e-23
 Identities = 58/162 (35%), Positives = 94/162 (58%)
 Frame = +3

Query: 9   VGDELVIDGGMATFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLST 188
           VG+ +++D G+   EVT   G  + CK  + G L     ++      L   +  LP L+ 
Sbjct: 119 VGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVN------LPGVSIALPALAE 172

Query: 189 KDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLKD 368
           KD  D+ FG  +GVD +A SF++  +D+  ++ +L     E+I+I +KIE+ E L N  +
Sbjct: 173 KDKQDLIFGCEQGVDFVAASFIRKRSDVVEIREHLKAHGGENIQIISKIENQEGLNNFDE 232

Query: 369 IIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           I+ ASDG+MVARGDLGV++P+ ++   Q+ ++E C    K V
Sbjct: 233 ILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVV 274
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>KPYK_YARLI (P30614) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 515

 Score =  107 bits (266), Expect = 2e-23
 Identities = 59/163 (36%), Positives = 98/163 (60%), Gaps = 1/163 (0%)
 Frame = +3

Query: 9   VGDELVIDGGMATFEVTEKIGGD-LRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLS 185
           +G  + +D G+ +F+V EKI G+ L+ +  + G      K+S  +   L   +  LP LS
Sbjct: 150 IGKIIFVDDGVLSFKVLEKIDGETLKVETLNNG------KISSRKGVNLPGTDVDLPALS 203

Query: 186 TKDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLK 365
            KD AD++FG+  GVD I  SFV+ AND+ +++  L  +  + I++ +KIE+ + + N  
Sbjct: 204 EKDKADLKFGVEHGVDMIFASFVRTANDVQAIRDVLGEKG-KGIQVISKIENQQGVNNFD 262

Query: 366 DIIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           +I+  +DGVMVARGDLG+++P  Q+   Q+ ++  C    KPV
Sbjct: 263 EILKETDGVMVARGDLGIEIPAPQVFIAQKQLIAKCNLAGKPV 305
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>KPYK1_ECOLI (P0AD61) Pyruvate kinase I (EC 2.7.1.40) (PK-1)|
          Length = 470

 Score =  106 bits (265), Expect = 3e-23
 Identities = 58/162 (35%), Positives = 93/162 (57%)
 Frame = +3

Query: 9   VGDELVIDGGMATFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLST 188
           VG+ +++D G+   EVT   G  + CK  + G L     ++      L   +  LP L+ 
Sbjct: 119 VGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVN------LPGVSIALPALAE 172

Query: 189 KDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLKD 368
           KD  D+ FG  +GVD +A SF++  +D+  ++ +L     E+I I +KIE+ E L N  +
Sbjct: 173 KDKQDLIFGCEQGVDFVAASFIRKRSDVIEIREHLKAHGGENIHIISKIENQEGLNNFDE 232

Query: 369 IIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           I+ ASDG+MVARGDLGV++P+ ++   Q+ ++E C    K V
Sbjct: 233 ILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVV 274
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>KPYK1_ECO57 (P0AD62) Pyruvate kinase I (EC 2.7.1.40) (PK-1)|
          Length = 470

 Score =  106 bits (265), Expect = 3e-23
 Identities = 58/162 (35%), Positives = 93/162 (57%)
 Frame = +3

Query: 9   VGDELVIDGGMATFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLST 188
           VG+ +++D G+   EVT   G  + CK  + G L     ++      L   +  LP L+ 
Sbjct: 119 VGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVN------LPGVSIALPALAE 172

Query: 189 KDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLKD 368
           KD  D+ FG  +GVD +A SF++  +D+  ++ +L     E+I I +KIE+ E L N  +
Sbjct: 173 KDKQDLIFGCEQGVDFVAASFIRKRSDVIEIREHLKAHGGENIHIISKIENQEGLNNFDE 232

Query: 369 IIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           I+ ASDG+MVARGDLGV++P+ ++   Q+ ++E C    K V
Sbjct: 233 ILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVV 274
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>KPYK_CLOAB (O08309) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 473

 Score =  105 bits (262), Expect = 7e-23
 Identities = 53/161 (32%), Positives = 96/161 (59%)
 Frame = +3

Query: 12  GDELVIDGGMATFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLSTK 191
           G+ ++ID G+    V    G ++ C   + GL+     ++      +   +  LP ++ K
Sbjct: 119 GNTILIDDGLVGLTVEAIEGTNVICTVANTGLVGSHKGVN------VPNVSIQLPAMTEK 172

Query: 192 DWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLKDI 371
           D +D+ FG  E +D ++ SF++   D+ +++  L+    E+I+IF+KIE+ E + N+  I
Sbjct: 173 DKSDLIFGCKEEIDMVSASFIRKPEDVLAIRKVLNENGGENIQIFSKIENQEGVDNIDAI 232

Query: 372 IXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           I  SDG+MVARGD+GV++P+ ++P IQ+ I++ C  + KPV
Sbjct: 233 IEVSDGIMVARGDMGVEIPIQRVPLIQKMIIKKCNAVGKPV 273
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>KPYK_BACPY (P51182) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 586

 Score =  105 bits (261), Expect = 9e-23
 Identities = 59/161 (36%), Positives = 95/161 (59%)
 Frame = +3

Query: 12  GDELVIDGGMATFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLSTK 191
           G  +++D G+   EVT   G D+  +     L++    LS  +   +   +  LP ++ K
Sbjct: 118 GSVILLDDGLIQLEVT---GKDV-ARGLIHTLIINSGSLSNNKGVNIPGVSVQLPGMTEK 173

Query: 192 DWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLKDI 371
           D  DI FGI EGVD IA SFV+ A+D+  ++  L   +  +++I  KIE+ E + N+ +I
Sbjct: 174 DAEDILFGIREGVDFIAASFVRRASDVMEIRALLENNNGSNLQIIPKIENQEGVDNIDEI 233

Query: 372 IXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           +  SDG+MVARGDLGV++P  ++P +Q+ ++E C    KPV
Sbjct: 234 LNVSDGLMVARGDLGVEIPPEEVPLVQKNLIEKCNQAGKPV 274
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>KPYK_CLOPE (Q46289) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 474

 Score =  104 bits (259), Expect = 1e-22
 Identities = 55/161 (34%), Positives = 91/161 (56%)
 Frame = +3

Query: 12  GDELVIDGGMATFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLSTK 191
           G  +++D G+  F+V E  G D+ C+  + G +     ++      +      LP ++ K
Sbjct: 119 GGSILVDDGLLEFKVKEVRGTDIICEVIEGGTIKDHKGVN------VPNVPIKLPAVTEK 172

Query: 192 DWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLKDI 371
           D +D+ FG    VD +A SF++   D+  ++  L     + IKI +KIES E + N+K+I
Sbjct: 173 DRSDLIFGCEMEVDFVAASFIRKPEDVLEVREILDSHGGKDIKIISKIESQEGVDNIKEI 232

Query: 372 IXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           I  +DGVMVARGD+GV++P+  +P IQ+ I++ C    K V
Sbjct: 233 IKVTDGVMVARGDMGVEIPIENVPIIQKNIIKKCNQAGKIV 273
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>KPYK_BACLI (P51181) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 585

 Score =  103 bits (258), Expect = 2e-22
 Identities = 58/166 (34%), Positives = 96/166 (57%), Gaps = 2/166 (1%)
 Frame = +3

Query: 3   ILVGDELVIDGGMATFEVTE--KIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLP 176
           + VG  +++D G+   EVT+  K   ++  K  + G L  +  ++      +   +  LP
Sbjct: 115 VSVGSTILLDDGLVGLEVTDINKDKREIVTKVMNSGTLKNKKGVN------VPGVSVNLP 168

Query: 177 TLSTKDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLK 356
            ++ KD  DI FGI +GVD IA SFV+  +D+  ++  L   +   I+I  KIE+ E + 
Sbjct: 169 GITEKDANDIVFGIEQGVDFIAASFVRRPSDVLEIRELLEEHNAADIQIIPKIENQEGVD 228

Query: 357 NLKDIIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           N+  I+  SDG+MVARGDLGV++P  ++P +Q+ +++ C  L KPV
Sbjct: 229 NIDAILEVSDGLMVARGDLGVEIPAEEVPLVQKELIKKCNALGKPV 274
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>KPYK_LACDE (P34038) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 589

 Score =  102 bits (255), Expect = 4e-22
 Identities = 55/164 (33%), Positives = 93/164 (56%), Gaps = 2/164 (1%)
 Frame = +3

Query: 9   VGDELVIDGGMA--TFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTL 182
           VG  ++ID G    T +  ++   +L C+  + G++   +K      G  +     LP +
Sbjct: 118 VGGTVLIDDGAVGLTIKAKDEEKRELVCEAQNTGVI--GSKKGVNAPGVEIR----LPGI 171

Query: 183 STKDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNL 362
           + KD  DI FG+  G++ I  SFV+ A D+  ++      +  ++KIF KIES E + N+
Sbjct: 172 TEKDTDDIRFGLKHGINFIFASFVRKAQDVLDIRALCEEANASYVKIFPKIESQEGIDNI 231

Query: 363 KDIIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
            +I+  SDG+MVARGD+GV++P   +P +Q+ +++ C  L KPV
Sbjct: 232 DEILQVSDGLMVARGDMGVEIPFINVPFVQKTLIKKCNALGKPV 275
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>KPYK_KLULA (Q875M9) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 501

 Score =  100 bits (249), Expect = 2e-21
 Identities = 57/165 (34%), Positives = 93/165 (56%), Gaps = 1/165 (0%)
 Frame = +3

Query: 3   ILVGDELVIDGGMATFEVTEKIGGD-LRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPT 179
           I  G  + +D G+ +FEV E I  + L+ K  + G      K+   +   L   +  LP 
Sbjct: 138 IEAGRIIYVDDGVLSFEVLEVIDDNTLKVKSLNAG------KICSHKGVNLPGTDVDLPA 191

Query: 180 LSTKDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKN 359
           LS KD +D++FG+  GV  +  SF++ A D+ +++  L  +  + IKI  KIE+ + + N
Sbjct: 192 LSEKDKSDLKFGVKNGVHMVFASFIRTAQDVLTIREVLGEQGKD-IKIIVKIENQQGVNN 250

Query: 360 LKDIIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
             DI+  +DGVMVARGDLG+++P  Q+  +Q+ ++  C    KPV
Sbjct: 251 FDDILKVTDGVMVARGDLGIEIPAPQVFAVQKKLIAKCNLAGKPV 295
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>KPYK_SCHPO (Q10208) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 509

 Score =  100 bits (249), Expect = 2e-21
 Identities = 56/162 (34%), Positives = 91/162 (56%), Gaps = 1/162 (0%)
 Frame = +3

Query: 12  GDELVIDGGMATFEVTEKIGG-DLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLST 188
           G  + +D G+ +F V EK+   +L+ +  + G      K+S  +   L + +  LP LS 
Sbjct: 147 GRIIYVDDGILSFTVIEKVDDKNLKVRVNNNG------KISSKKGVNLPKTDVDLPALSE 200

Query: 189 KDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLKD 368
           KD AD+ FG+  GVD I  SF++ A D+  ++  L     ++IKI  KIE+ + + N   
Sbjct: 201 KDKADLRFGVKNGVDMIFASFIRRAEDVIHIREVLGEEG-KNIKIICKIENQQGVNNFDS 259

Query: 369 IIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           I+  +DG+MVARGDLG+++P  Q+   Q+ ++  C    KPV
Sbjct: 260 ILDVTDGIMVARGDLGIEIPASQVFVAQKMMIAKCNIAGKPV 301
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>KPYK_BACSU (P80885) Pyruvate kinase (EC 2.7.1.40) (PK) (Vegetative protein 17)|
           (VEG17)
          Length = 585

 Score =  100 bits (249), Expect = 2e-21
 Identities = 54/163 (33%), Positives = 94/163 (57%), Gaps = 2/163 (1%)
 Frame = +3

Query: 12  GDELVIDGGMATFEVTEKIGG--DLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLS 185
           G  +++D G+   EV +      +++ K  + G L  +  ++      +   +  LP ++
Sbjct: 118 GSTILLDDGLIGLEVLDVDAAKREIKTKVLNNGTLKNKKGVN------VPGVSVNLPGIT 171

Query: 186 TKDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLK 365
            KD  DI FGI +GVD IA SF++ + D+  ++  L   + + I+I  KIE+ E + N+ 
Sbjct: 172 EKDARDIVFGIEQGVDFIAPSFIRRSTDVLEIRELLEEHNAQDIQIIPKIENQEGVDNID 231

Query: 366 DIIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
            I+  SDG+MVARGDLGV++P  ++P +Q+ +++ C  L KPV
Sbjct: 232 AILEVSDGLMVARGDLGVEIPAEEVPLVQKELIKKCNALGKPV 274
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>KPYK_ASHGO (Q759A9) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 501

 Score = 98.2 bits (243), Expect = 1e-20
 Identities = 56/162 (34%), Positives = 90/162 (55%), Gaps = 1/162 (0%)
 Frame = +3

Query: 12  GDELVIDGGMATFEVTEKIGGD-LRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLST 188
           G  + +D G+ +FEV E +    L+ K  + G      K+   +   L   +  LP LS 
Sbjct: 141 GRVIYVDDGVLSFEVLEVVDDKTLKVKSLNAG------KICSHKGVNLPGTDVDLPALSE 194

Query: 189 KDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLKD 368
           KD +D+ FG+  GV  +  SF++ A DI +++  L     + IKI AKIE+ + + N  +
Sbjct: 195 KDKSDLRFGVKNGVHMVFASFIRTAGDILTIREILGEDGKD-IKIIAKIENQQGVNNFDE 253

Query: 369 IIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           I+  +DGVMVARGDLG+++P  Q+  +Q+ ++  C    KPV
Sbjct: 254 ILKVTDGVMVARGDLGIEIPAPQVFAVQKMLIAKCNLAGKPV 295
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>KPYK_NEUCR (Q7RVA8) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 527

 Score = 97.1 bits (240), Expect = 2e-20
 Identities = 56/165 (33%), Positives = 89/165 (53%), Gaps = 1/165 (0%)
 Frame = +3

Query: 3   ILVGDELVIDGGMATFEVTEKIGGD-LRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPT 179
           I  G  + +D G+  FEV E +    ++ K  + G +  R  ++      L   +  LP 
Sbjct: 150 IAPGRIIYVDDGVLAFEVLEIVDDKTIKVKARNNGYISSRKGVN------LPNTDVDLPA 203

Query: 180 LSTKDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKN 359
           LS KD AD+ FG+   VD +  SF++   DI  ++  L     + I+I AKIE+ + L N
Sbjct: 204 LSEKDKADLRFGVKNKVDMVFASFIRRGQDIKDIREVLGEDG-KQIQIIAKIENRQGLNN 262

Query: 360 LKDIIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
             +I+  +DGVMVARGDLG+++P  ++   Q+ I+ +C    KPV
Sbjct: 263 FAEILAETDGVMVARGDLGIEIPAAEVFAAQKKIIAMCNIAGKPV 307
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>KPYK_MYCTU (O06134) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 472

 Score = 96.7 bits (239), Expect = 3e-20
 Identities = 55/163 (33%), Positives = 86/163 (52%)
 Frame = +3

Query: 6   LVGDELVIDGGMATFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLS 185
           + GD +++D G     V    G D+ C   + G +     +S      L   N   P LS
Sbjct: 117 VAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGIS------LPGMNVTAPALS 170

Query: 186 TKDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLK 365
            KD  D+ F +  GVD +ALSFV+   D+  +   + R     + + AK+E  E++ NL+
Sbjct: 171 EKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIG-RRVPVIAKLEKPEAIDNLE 229

Query: 366 DIIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
            I+ A D VMVARGDLGV++PL ++P +Q+  +++     KPV
Sbjct: 230 AIVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPV 272
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>KPYK_CHICK (P00548) Pyruvate kinase muscle isozyme (EC 2.7.1.40)|
          Length = 529

 Score = 96.7 bits (239), Expect = 3e-20
 Identities = 52/162 (32%), Positives = 95/162 (58%)
 Frame = +3

Query: 9   VGDELVIDGGMATFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLST 188
           VG ++ +D G+ +  V EK    +  +  + G+L  +  ++    G  V+    LP +S 
Sbjct: 168 VGSKIYVDDGLISLLVKEKGKDFVMTEVENGGMLGSKKGVNL--PGAAVD----LPAVSE 221

Query: 189 KDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLKD 368
           KD  D++FG+ + VD +  SF++ A D+ +++  L  +  +HIKI +KIE+ E ++   +
Sbjct: 222 KDIQDLKFGVEQNVDMVFASFIRKAADVHAVRKVLGEKG-KHIKIISKIENHEGVRRFDE 280

Query: 369 IIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           I+ ASDG+MVARGDLG+++P  ++   Q+ ++  C    KP+
Sbjct: 281 IMEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPI 322
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>KPYK_MYCIT (P94939) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 472

 Score = 96.3 bits (238), Expect = 4e-20
 Identities = 55/162 (33%), Positives = 86/162 (53%)
 Frame = +3

Query: 9   VGDELVIDGGMATFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLST 188
           VGD +++D G     V    G D+ C   + G +     +S      L   N   P LS 
Sbjct: 118 VGDRVLVDDGKVCLVVDGIEGDDVICTVVEGGPVSNNKGIS------LPGMNVSAPALSE 171

Query: 189 KDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLKD 368
           KD  D+ F +  GVD +ALSFV+   D+  +   + R     + + AK+E  E++ NL+ 
Sbjct: 172 KDIEDLTFALDLGVDLVALSFVRSPADVELVHEVMDRVG-RRVPVIAKLEKPEAVDNLET 230

Query: 369 IIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           I+ A D +MVARGDLGV++PL ++P +Q+  +++     KPV
Sbjct: 231 IVLAFDAIMVARGDLGVELPLEEVPLVQKRAIQMARENAKPV 272
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>KPYK2_CANGA (Q6FV12) Pyruvate kinase 2 (EC 2.7.1.40) (PK 2)|
          Length = 508

 Score = 96.3 bits (238), Expect = 4e-20
 Identities = 54/162 (33%), Positives = 88/162 (54%), Gaps = 1/162 (0%)
 Frame = +3

Query: 12  GDELVIDGGMATFEVTEKIGGD-LRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLST 188
           G  + +D G+ +FEV E +    L+ K  + G      K+S  +   L   +  LP LS 
Sbjct: 141 GKVIYVDDGVLSFEVLEVVDDKTLKVKSLNAG------KISSHKGVNLPGTDVDLPALSE 194

Query: 189 KDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLKD 368
           KD  D+ FG+  GV  I  SF++ A D+ +++  L     + IK+  KIE+ + + N  +
Sbjct: 195 KDKEDLRFGVKNGVHMIFASFIRTAQDVLTIREVLGEEGKD-IKVIVKIENQQGVNNFDE 253

Query: 369 IIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           I+  + GVMVARGDLG+++P  Q+  +Q+ ++  C    KPV
Sbjct: 254 ILEVAHGVMVARGDLGIEIPAPQVLAVQKKLIAKCNLAGKPV 295
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>KPYM_PONPY (Q5NVN0) Pyruvate kinase isozyme M1 (EC 2.7.1.40)|
          Length = 530

 Score = 95.9 bits (237), Expect = 5e-20
 Identities = 52/162 (32%), Positives = 95/162 (58%)
 Frame = +3

Query: 9   VGDELVIDGGMATFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLST 188
           VG ++ +D G+ + +V +K    L  +  + G L  +  ++    G  V+    LP +S 
Sbjct: 169 VGSKIYVDDGLISLQVKQKGADFLLTEVENGGSLGSKKGVNL--PGAAVD----LPAVSE 222

Query: 189 KDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLKD 368
           KD  D++FG+ + VD +  SF++ A+D+  ++  L  +  ++IKI +KIE+ E ++   +
Sbjct: 223 KDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKG-KNIKIISKIENHEGVRRFDE 281

Query: 369 IIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           I+ ASDG+MVARGDLG+++P  ++   Q+ ++  C    KPV
Sbjct: 282 ILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPV 323
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>KPYK_SACKL (Q875S4) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 501

 Score = 95.9 bits (237), Expect = 5e-20
 Identities = 53/162 (32%), Positives = 89/162 (54%), Gaps = 1/162 (0%)
 Frame = +3

Query: 12  GDELVIDGGMATFEVTEKIGGD-LRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLST 188
           G  + +D G+ +FEV E +    L+ K  + G      K+   +   L   +  LP LS 
Sbjct: 141 GKIIYVDDGVLSFEVLEVVDEQTLKVKSLNAG------KICSHKGVNLPGTDVDLPALSE 194

Query: 189 KDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLKD 368
           KD +D+ FG+  GV  +  SF++ A D+ +++  L     + +KI  KIE+ + + N  +
Sbjct: 195 KDKSDLRFGVKNGVHMVFASFIRTAQDVLTIREVLGEDGKD-VKIIVKIENQQGVNNFDE 253

Query: 369 IIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           I+  +DGVMVARGDLG+++P  Q+  +Q+ ++  C    KPV
Sbjct: 254 ILKVTDGVMVARGDLGIEIPAPQVFAVQKKLIAKCNLAGKPV 295
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>KPYK_DEBHA (Q6BS75) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 504

 Score = 95.9 bits (237), Expect = 5e-20
 Identities = 57/165 (34%), Positives = 91/165 (55%), Gaps = 1/165 (0%)
 Frame = +3

Query: 3   ILVGDELVIDGGMATFEVTEKIGGD-LRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPT 179
           I  G  + ID G+ +FEV + +    L+ +  + G      K+   +   L   +  LP 
Sbjct: 141 IEAGKIIYIDDGVVSFEVLQIVDDKTLKVRSVNSG------KICSHKGVNLPGTDVDLPA 194

Query: 180 LSTKDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKN 359
           LS KD ADI+FG+  GV  I  SF++  +DI  ++  L     + I+I AKIE+ + + N
Sbjct: 195 LSEKDKADIKFGVKNGVHMIFASFIRTGDDIKEIRKVLGEEGKD-IQIIAKIENQQGVNN 253

Query: 360 LKDIIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
             +I+  +DGVMVARGDLG+++P  Q+  +Q+ ++  C    KPV
Sbjct: 254 FDEILVETDGVMVARGDLGIEIPAPQVFVVQKQLIAKCNLAAKPV 298
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>KPYK_EMENI (P22360) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 526

 Score = 95.9 bits (237), Expect = 5e-20
 Identities = 56/165 (33%), Positives = 92/165 (55%), Gaps = 1/165 (0%)
 Frame = +3

Query: 3   ILVGDELVIDGGMATFEVTEKIGGD-LRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPT 179
           I  G  + +D G+ +FEV E +    LR +C + G +  R  ++      L   +  LP 
Sbjct: 151 ISAGKLIYVDDGILSFEVLEVVDDKTLRVRCLNNGNISSRKGVN------LPGTDVDLPA 204

Query: 180 LSTKDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKN 359
           LS KD +D++FG+   VD +  SF++  +DI  ++  L     E I+I AKIE+ + + N
Sbjct: 205 LSEKDISDLKFGVKNKVDMVFASFIRRGSDIRHIREVLGEEGRE-IQIIAKIENQQGVNN 263

Query: 360 LKDIIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
             +I+  +DGVMVARGDLG+++P  ++   Q+ ++  C    KPV
Sbjct: 264 FDEILEETDGVMVARGDLGIEIPAPKVFIAQKMMIAKCNIKGKPV 308
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>KPYM_RAT (P11980) Pyruvate kinase isozymes M1/M2 (EC 2.7.1.40) (Pyruvate|
           kinase muscle isozyme)
          Length = 530

 Score = 95.5 bits (236), Expect = 7e-20
 Identities = 53/162 (32%), Positives = 94/162 (58%)
 Frame = +3

Query: 9   VGDELVIDGGMATFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLST 188
           VG ++ +D G+ + +V EK    L  +  + G L  +  ++    G  V+    LP +S 
Sbjct: 169 VGSKIYVDDGLISLQVKEKGADYLVTEVENGGSLGSKKGVNL--PGAAVD----LPAVSE 222

Query: 189 KDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLKD 368
           KD  D++FG+ + VD +  SF++ A D+  ++  L  +  ++IKI +KIE+ E ++   +
Sbjct: 223 KDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKVLGEKG-KNIKIISKIENHEGVRRFDE 281

Query: 369 IIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           I+ ASDG+MVARGDLG+++P  ++   Q+ ++  C    KPV
Sbjct: 282 ILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPV 323
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>KPYM_MOUSE (P52480) Pyruvate kinase isozyme M2 (EC 2.7.1.40)|
          Length = 530

 Score = 95.5 bits (236), Expect = 7e-20
 Identities = 53/162 (32%), Positives = 94/162 (58%)
 Frame = +3

Query: 9   VGDELVIDGGMATFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLST 188
           VG ++ +D G+ + +V EK    L  +  + G L  +  ++    G  V+    LP +S 
Sbjct: 169 VGSKIYVDDGLISLQVKEKGADFLVTEVENGGSLGSKKGVNL--PGAAVD----LPAVSE 222

Query: 189 KDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLKD 368
           KD  D++FG+ + VD +  SF++ A D+  ++  L  +  ++IKI +KIE+ E ++   +
Sbjct: 223 KDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKVLGEKG-KNIKIISKIENHEGVRRFDE 281

Query: 369 IIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           I+ ASDG+MVARGDLG+++P  ++   Q+ ++  C    KPV
Sbjct: 282 ILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPV 323
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>KPYM_HUMAN (P14618) Pyruvate kinase isozymes M1/M2 (EC 2.7.1.40) (Pyruvate|
           kinase muscle isozyme) (Cytosolic thyroid
           hormone-binding protein) (CTHBP) (THBP1)
          Length = 530

 Score = 95.5 bits (236), Expect = 7e-20
 Identities = 52/162 (32%), Positives = 95/162 (58%)
 Frame = +3

Query: 9   VGDELVIDGGMATFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLST 188
           VG ++ +D G+ + +V +K    L  +  + G L  +  ++    G  V+    LP +S 
Sbjct: 169 VGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVNL--PGAAVD----LPAVSE 222

Query: 189 KDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLKD 368
           KD  D++FG+ + VD +  SF++ A+D+  ++  L  +  ++IKI +KIE+ E ++   +
Sbjct: 223 KDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKG-KNIKIISKIENHEGVRRFDE 281

Query: 369 IIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           I+ ASDG+MVARGDLG+++P  ++   Q+ ++  C    KPV
Sbjct: 282 ILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPV 323
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>KPYK_COREF (Q8FP04) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 474

 Score = 95.5 bits (236), Expect = 7e-20
 Identities = 54/161 (33%), Positives = 85/161 (52%)
 Frame = +3

Query: 12  GDELVIDGGMATFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLSTK 191
           GD L++D G          G D+ C+ T+ G +     +S      L   +  +P LS K
Sbjct: 119 GDRLLVDDGKVGLVCVSVEGNDVICEVTEGGPVSNNKGVS------LPGMDISVPALSEK 172

Query: 192 DWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLKDI 371
           D  D+ F +  GVD IALSFV+   D+  +   +       + + AK+E  E++  L+ I
Sbjct: 173 DIKDLRFALKLGVDFIALSFVRSPADVELVHAIMDEEG-RRVPVIAKLEKPEAVAALESI 231

Query: 372 IXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           + A D +MVARGDLGV+VPL ++P +Q+  +++     KPV
Sbjct: 232 VLAFDAIMVARGDLGVEVPLEEVPLVQKRAIQIARENAKPV 272
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>KPYK_ASPNG (Q12669) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 526

 Score = 95.5 bits (236), Expect = 7e-20
 Identities = 55/162 (33%), Positives = 91/162 (56%), Gaps = 1/162 (0%)
 Frame = +3

Query: 12  GDELVIDGGMATFEVTEKIGGD-LRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLST 188
           G  + +D G+ +FEV E +    +R +C + G +  R  ++      L   +  LP LS 
Sbjct: 154 GKLIYVDDGILSFEVLEVVDDKTIRVRCLNNGNISSRKGVN------LPGTDVDLPALSE 207

Query: 189 KDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLKD 368
           KD AD++FG+   VD +  SF++  +DI  ++  L     E I+I AKIE+ + + N  +
Sbjct: 208 KDIADLKFGVRNKVDMVFASFIRRGSDIRHIREVLGEEGKE-IQIIAKIENQQGVNNFDE 266

Query: 369 IIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           I+  +DGVMVARGDLG+++P  ++   Q+ ++  C    KPV
Sbjct: 267 ILEETDGVMVARGDLGIEIPAPKVFIAQKMMIAKCNIKGKPV 308
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>KPYK2_AGRVI (Q44473) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 482

 Score = 95.1 bits (235), Expect = 9e-20
 Identities = 58/161 (36%), Positives = 91/161 (56%)
 Frame = +3

Query: 12  GDELVIDGGMATFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLSTK 191
           G +L+ID G     + E + G L C+  + G L  R  ++    G +++    +  L+ K
Sbjct: 124 GMDLLIDDGRIKVRIMEVMDGRLVCEVLNGGALSNRKGVNV--PGAVLD----ISPLTAK 177

Query: 192 DWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLKDI 371
           D  D+EFG+  GVD +ALSFV+ A D+   ++ +  R+     + AKIE   +L +++DI
Sbjct: 178 DREDLEFGLELGVDWVALSFVQRARDMIEARSLVGDRA----GLIAKIEKPSALDDIEDI 233

Query: 372 IXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           +  SD VMVARGDLGV++P   +P  Q+ I+  C    KPV
Sbjct: 234 VRLSDSVMVARGDLGVEIPPEDVPGKQKEIIRACRLAAKPV 274
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>KPYM_RABIT (P11974) Pyruvate kinase isozymes M1/M2 (EC 2.7.1.40) (Pyruvate|
           kinase muscle isozyme)
          Length = 530

 Score = 95.1 bits (235), Expect = 9e-20
 Identities = 53/162 (32%), Positives = 94/162 (58%)
 Frame = +3

Query: 9   VGDELVIDGGMATFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLST 188
           VG ++ +D G+ + +V +K    L  +  + G L  +  ++    G  V+    LP +S 
Sbjct: 169 VGSKVYVDDGLISLQVKQKGPDFLVTEVENGGFLGSKKGVNL--PGAAVD----LPAVSE 222

Query: 189 KDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLKD 368
           KD  D++FG+ + VD +  SF++ A D+  ++  L  +  ++IKI +KIE+ E ++   +
Sbjct: 223 KDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKILGEKG-KNIKIISKIENHEGVRRFDE 281

Query: 369 IIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           I+ ASDG+MVARGDLG+++P  ++   Q+ I+  C    KPV
Sbjct: 282 ILEASDGIMVARGDLGIEIPAEKVFLAQKMIIGRCNRAGKPV 323
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>KPYK_DROME (O62619) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 533

 Score = 95.1 bits (235), Expect = 9e-20
 Identities = 55/161 (34%), Positives = 93/161 (57%)
 Frame = +3

Query: 12  GDELVIDGGMATFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLSTK 191
           G+ + +D G+ +  V E     L C+  + G L  R  ++    G  V+    LP +S K
Sbjct: 174 GNRVFVDDGLISLIVREVGKDSLTCEVENGGSLGSRKGVNL--PGVPVD----LPAVSEK 227

Query: 192 DWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLKDI 371
           D +D+ FG+ + VD I  SF+++A  +  ++  L  +  ++IKI +KIE+ + + NL +I
Sbjct: 228 DKSDLLFGVEQEVDMIFASFIRNAAALTEIRKVLGEKG-KNIKIISKIENQQGMHNLDEI 286

Query: 372 IXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           I A DG+MVARGDLG+++P  ++   Q+A++  C    KPV
Sbjct: 287 IEAGDGIMVARGDLGIEIPAEKVFLAQKAMIARCNKAGKPV 327
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>KPYK_METEX (O05118) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 483

 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 58/158 (36%), Positives = 85/158 (53%)
 Frame = +3

Query: 21  LVIDGGMATFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLSTKDWA 200
           ++ID G     VTE   G    +    G +  R  +S      L      +P ++ KD  
Sbjct: 129 ILIDDGKLRLIVTEVSEGRAVTRVEVGGRISNRKGVS------LPHTALPVPAMTEKDRG 182

Query: 201 DIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLKDIIXA 380
           D+E G+  G D IA+SFV+   D+  +K   + R+L    + AKIE  ++L  L +II  
Sbjct: 183 DLEAGLAAGADWIAVSFVQRPEDVAEVKKVAAGRAL----VMAKIEKPQALTRLDEIIEI 238

Query: 381 SDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           SDG+MVARGDLGV++PL Q+P +Q+ I  +   L KPV
Sbjct: 239 SDGIMVARGDLGVEMPLEQVPGVQKRITRVARRLGKPV 276
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>KPYM_FELCA (P11979) Pyruvate kinase isozyme M1 (EC 2.7.1.40) (Pyruvate kinase|
           muscle isozyme)
          Length = 530

 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 53/162 (32%), Positives = 94/162 (58%)
 Frame = +3

Query: 9   VGDELVIDGGMATFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLST 188
           VG ++ +D G+ +  V EK    L  +  + G L  +  ++    G  V+    LP +S 
Sbjct: 169 VGSKVYVDDGLISLLVKEKGADFLVTEVENGGSLGSKKGVNL--PGAAVD----LPAVSE 222

Query: 189 KDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLKD 368
           KD  D++FG+ + VD +  SF++ A+D+  ++  L  +  ++IKI +KIE+ E ++   +
Sbjct: 223 KDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKG-KNIKIISKIENHEGVRRFDE 281

Query: 369 IIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           I+ ASDG+MVARGDLG+++P  ++   Q+ ++  C    KPV
Sbjct: 282 ILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPV 323
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>KPYK2_TRYBB (P30616) Pyruvate kinase 2 (EC 2.7.1.40) (PK 2)|
          Length = 499

 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 56/163 (34%), Positives = 88/163 (53%), Gaps = 1/163 (0%)
 Frame = +3

Query: 9   VGDELVIDGGMATFEVTEKIGG-DLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLS 185
           VG  + +D G+ T  V  K     L+C   +   L  R  ++      L      LP +S
Sbjct: 138 VGGSIYVDDGVMTLRVLSKEDDRTLKCHVNNHHRLTDRRGIN------LPGCEVDLPAVS 191

Query: 186 TKDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLK 365
            KD  D+EFG+ +GVD I  SF++ A  +  ++  L  +  + I I +KIE+ + ++N+ 
Sbjct: 192 EKDRKDLEFGVAQGVDMIFASFIRTAEQVREVRAALGEKGKD-ILIISKIENHQGVQNID 250

Query: 366 DIIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
            II AS+G+MVARGDLGV++P  ++   Q  I+  C  + KPV
Sbjct: 251 SIIEASNGIMVARGDLGVEIPAEKVCVAQMCIISKCNVVGKPV 293
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>KPYK1_YEAST (P00549) Pyruvate kinase 1 (EC 2.7.1.40) (PK 1)|
          Length = 500

 Score = 93.6 bits (231), Expect = 3e-19
 Identities = 52/165 (31%), Positives = 90/165 (54%), Gaps = 1/165 (0%)
 Frame = +3

Query: 3   ILVGDELVIDGGMATFEVTEKIGGD-LRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPT 179
           I  G  + +D G+ +F+V E +    L+ K  + G      K+   +   L   +  LP 
Sbjct: 137 ISAGRIIYVDDGVLSFQVLEVVDDKTLKVKALNAG------KICSHKGVNLPGTDVDLPA 190

Query: 180 LSTKDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKN 359
           LS KD  D+ FG+  GV  +  SF++ AND+ +++  L  +  + +KI  KIE+ + + N
Sbjct: 191 LSEKDKEDLRFGVKNGVHMVFASFIRTANDVLTIREVLGEQGKD-VKIIVKIENQQGVNN 249

Query: 360 LKDIIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
             +I+  +DGVMVARGDLG+++P  ++  +Q+ ++       KPV
Sbjct: 250 FDEILKVTDGVMVARGDLGIEIPAPEVLAVQKKLIAKSNLAGKPV 294
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>KPYK_TRIRE (P31865) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 538

 Score = 93.2 bits (230), Expect = 3e-19
 Identities = 53/162 (32%), Positives = 87/162 (53%), Gaps = 1/162 (0%)
 Frame = +3

Query: 12  GDELVIDGGMATFEVTE-KIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLST 188
           G  + +D G+  F+V   K    +  +  + G +  R  ++      L   +  LP LS 
Sbjct: 163 GRVIYVDDGVLAFDVLSIKDDQTVEVRARNNGFISSRKGVN------LPNTDVDLPALSE 216

Query: 189 KDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLKD 368
           KD AD+ FG+   VD +  SF++ A DI  ++  L     + I+I AKIE+ + L N  +
Sbjct: 217 KDKADLRFGVKNNVDMVFASFIRRAQDIKDIRDVLGPEG-KQIQIIAKIENRQGLNNFAE 275

Query: 369 IIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           I+  +DGVMVARGDLG+++P  ++   Q+ ++ +C    KPV
Sbjct: 276 ILEETDGVMVARGDLGIEIPAAEVFAAQKKMIAMCNIAGKPV 317
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>KPYK1_TRYBB (P30615) Pyruvate kinase 1 (EC 2.7.1.40) (PK 1)|
          Length = 499

 Score = 93.2 bits (230), Expect = 3e-19
 Identities = 55/162 (33%), Positives = 87/162 (53%), Gaps = 1/162 (0%)
 Frame = +3

Query: 12  GDELVIDGGMATFEVTEKIGG-DLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLST 188
           G  + +D G+ T  V  K     L+C   +   L  R  ++      L      LP +S 
Sbjct: 139 GGSIYVDDGVMTLRVVSKEDDRTLKCHVNNHHRLTDRRGIN------LPGCEVDLPAVSE 192

Query: 189 KDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLKD 368
           KD  D+EFG+ +GVD I  SF++ A  +  ++  L  +  + I I +KIE+ + ++N+  
Sbjct: 193 KDRKDLEFGVAQGVDMIFASFIRTAEQVREVRAALGEKGKD-ILIISKIENHQGVQNIDS 251

Query: 369 IIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           II AS+G+MVARGDLGV++P  ++   Q  I+  C  + KPV
Sbjct: 252 IIEASNGIMVARGDLGVEIPAEKVCVAQMCIISKCNVVGKPV 293
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>KPYK2_YEAST (P52489) Pyruvate kinase 2 (EC 2.7.1.40) (PK 2)|
          Length = 506

 Score = 93.2 bits (230), Expect = 3e-19
 Identities = 51/165 (30%), Positives = 92/165 (55%), Gaps = 1/165 (0%)
 Frame = +3

Query: 3   ILVGDELVIDGGMATFEVTEKIG-GDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPT 179
           I+ G  + +D G+ +F+V + I   +LR +  + G +     ++      L   +  LP 
Sbjct: 139 IVPGRFIYVDDGILSFKVLQIIDESNLRVQAVNSGYIASHKGVN------LPNTDVDLPP 192

Query: 180 LSTKDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKN 359
           LS KD  D++FG+  G+  +  SF++ + D+ S++  L     + IKI +KIE+ + L N
Sbjct: 193 LSAKDMKDLQFGVRNGIHIVFASFIRTSEDVLSIRKALGSEG-QDIKIISKIENQQGLDN 251

Query: 360 LKDIIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
             +I+  +DGVM+ARGDLG+++   ++  IQ+ ++  C    KPV
Sbjct: 252 FDEILEVTDGVMIARGDLGIEILAPEVLAIQKKLIAKCNLAGKPV 296
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>KPYK_LACLA (Q07637) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 502

 Score = 93.2 bits (230), Expect = 3e-19
 Identities = 52/173 (30%), Positives = 92/173 (53%), Gaps = 11/173 (6%)
 Frame = +3

Query: 9   VGDELVIDGGMATFEVTEKIGG--DLRCKCTDPGLL-------LPRAKLSFWRDGKLVER 161
           +G  ++ID G     +T K     +   +  + G++       +P  K+ F         
Sbjct: 145 IGQTILIDDGKLGLSLTGKDAATREFEVEAQNDGVIGKQKGVNIPNTKIPF--------- 195

Query: 162 NFGLPTLSTKDWADIEFGITE--GVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKI 335
               P L+ +D ADI FG+++  G++ IA+SFV+ AND+  ++         H+++ AKI
Sbjct: 196 ----PALAERDDADIRFGLSQPGGINFIAISFVRTANDVKEVRRICEETGNPHVQLLAKI 251

Query: 336 ESLESLKNLKDIIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           E+ + ++NL +II A+DG+M+ARGD+G++VP   +P  Q+ I+       K V
Sbjct: 252 ENQQGIENLDEIIEAADGIMIARGDMGIEVPFEMVPVYQKLIISKVNKAGKIV 304
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>KPYK_CORGL (Q46078) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 475

 Score = 92.8 bits (229), Expect = 4e-19
 Identities = 54/161 (33%), Positives = 84/161 (52%)
 Frame = +3

Query: 12  GDELVIDGGMATFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLSTK 191
           GD L++D G          G D+ C+  + G +     +S      L   +  +P LS K
Sbjct: 119 GDRLLVDDGKVGLVCVSVEGNDVICEVVEGGPVSNNKGVS------LPGMDISVPALSEK 172

Query: 192 DWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLKDI 371
           D  D+ F +  GVD IALSFV+   D   +   +       + + AK+E  E++ +L+ I
Sbjct: 173 DIRDLRFALKLGVDFIALSFVRSPADAELVHKIMDEEG-RRVPVIAKLEKPEAVTSLEPI 231

Query: 372 IXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           + A D VMVARGDLGV+VPL ++P +Q+  +++     KPV
Sbjct: 232 VLAFDAVMVARGDLGVEVPLEEVPLVQKRAIQIARENAKPV 272
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>KPYK_SACCA (Q875Z9) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 501

 Score = 92.8 bits (229), Expect = 4e-19
 Identities = 53/162 (32%), Positives = 88/162 (54%), Gaps = 1/162 (0%)
 Frame = +3

Query: 12  GDELVIDGGMATFEVTEKIGGD-LRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLST 188
           G  + +D G+ +FEV E + G  L+ K  + G      K+   +   L   +  LP LS 
Sbjct: 141 GKIIYVDDGVLSFEVLEVVDGKTLKVKSLNAG------KICSHKGVNLPGTDVDLPALSE 194

Query: 189 KDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLKD 368
           KD AD+ FG+  GV  +  SF++ A D+ +++  L     + IKI  KIE+ + + N  +
Sbjct: 195 KDKADLRFGVKNGVHMVFASFIRTAQDVLTIREVLGEDGKD-IKIVVKIENQQGVNNFDE 253

Query: 369 IIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           I+  +D VMVARGDLG+++P  ++  +Q+ ++       KPV
Sbjct: 254 ILKVTDAVMVARGDLGIEIPAPEVLAVQKKLIAKSNLAGKPV 295
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>KPYK_XENLA (Q92122) Pyruvate kinase muscle isozyme (EC 2.7.1.40) (Cytosolic|
           thyroid hormone-binding protein) (CTHBP)
          Length = 527

 Score = 92.0 bits (227), Expect = 8e-19
 Identities = 54/161 (33%), Positives = 93/161 (57%)
 Frame = +3

Query: 12  GDELVIDGGMATFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLSTK 191
           G ++ +D G+ +  V E IG D      + G +L  +K      G  V+    LP +S+K
Sbjct: 167 GSKIYVDDGLISLLVKE-IGPDFCVTEIENGGMLG-SKKGVNLPGAAVD----LPAVSSK 220

Query: 192 DWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLKDI 371
           D  D++FG+ + VD +  SF++ A D+  ++  L  +  ++IKI +KIE+ E ++   +I
Sbjct: 221 DIQDLQFGVEQDVDMVFASFIRKAADVHEVREVLGEKG-KNIKIISKIENHEGVRRFDEI 279

Query: 372 IXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           + ASDG+MVARGDLG+++P  ++   Q+ ++  C    KPV
Sbjct: 280 LEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPV 320
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>KPYR_RAT (P12928) Pyruvate kinase isozymes R/L (EC 2.7.1.40) (L-PK)|
          Length = 574

 Score = 92.0 bits (227), Expect = 8e-19
 Identities = 57/165 (34%), Positives = 92/165 (55%), Gaps = 1/165 (0%)
 Frame = +3

Query: 3   ILVGDELVIDGGMATFEVTEKIGGD-LRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPT 179
           + VG  + ID G+ +  V +KIG + L  +    G+L  R  ++      L      LP 
Sbjct: 211 VAVGGRIYIDDGLISL-VVQKIGPEGLVTEVEHGGILGSRKGVN------LPNTEVDLPG 263

Query: 180 LSTKDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKN 359
           LS +D  D+ FG+   VD I  SFV+ A+D+ +++  L     ++IKI +KIE+ E +K 
Sbjct: 264 LSEQDLLDLRFGVQHNVDIIFASFVRKASDVLAVRDALGPEG-QNIKIISKIENHEGVKK 322

Query: 360 LKDIIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
             +I+  SDG+MVARGDLG+++P  ++   Q+ ++  C    KPV
Sbjct: 323 FDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPV 367
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>KPYR_HUMAN (P30613) Pyruvate kinase isozymes R/L (EC 2.7.1.40) (R-type/L-type|
           pyruvate kinase) (Red cell/liver pyruvate kinase)
          Length = 574

 Score = 91.3 bits (225), Expect = 1e-18
 Identities = 58/163 (35%), Positives = 93/163 (57%), Gaps = 1/163 (0%)
 Frame = +3

Query: 9   VGDELVIDGGMATFEVTEKIGGD-LRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLS 185
           VG  + ID G+ +  V +KIG + L  +  + G+L  R  ++    G  V+    LP LS
Sbjct: 213 VGGRIYIDDGLISL-VVQKIGPEGLVTQVENGGVLGSRKGVNL--PGAQVD----LPGLS 265

Query: 186 TKDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLK 365
            +D  D+ FG+  GVD +  SFV+ A+D+ +++  L       IKI +KIE+ E +K   
Sbjct: 266 EQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEG-HGIKIISKIENHEGVKRFD 324

Query: 366 DIIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           +I+  SDG+MVARGDLG+++P  ++   Q+ ++  C    KPV
Sbjct: 325 EILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPV 367
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>KPYK_AGABI (O94122) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 532

 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 54/161 (33%), Positives = 85/161 (52%)
 Frame = +3

Query: 12  GDELVIDGGMATFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLSTK 191
           G  + ID G+ +  +    G +L  +  + G L  R  ++      L + +  LP LS K
Sbjct: 155 GKLIYIDDGIISLLILSIDGMNLHVRALNNGTLSSRKGVN------LPKTDVDLPPLSEK 208

Query: 192 DWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLKDI 371
           D  D+ FGI  GVD I  SF++   D+  ++  L       IKI  KIE+ + + N  +I
Sbjct: 209 DKDDLRFGIRNGVDMIFASFIRRGEDVRQIREVLGPDGAS-IKIIVKIENEQGVANFDEI 267

Query: 372 IXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           +  +DGVMVARGDLG+++P  Q+   Q+ ++  C  + KPV
Sbjct: 268 LKEADGVMVARGDLGIEIPASQVFLAQKMMIAKCNIVGKPV 308
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>KPYR_CANFA (Q29536) Pyruvate kinase isozyme R (EC 2.7.1.40) (Fragment)|
          Length = 519

 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 54/162 (33%), Positives = 87/162 (53%)
 Frame = +3

Query: 9   VGDELVIDGGMATFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLST 188
           VG  + ID G+ + +V +     L  +  + GLL  R  ++      L      LP LS 
Sbjct: 158 VGGRIFIDDGLISLQVKKIDRKGLETQVENGGLLGSRKGVN------LPGAEVDLPGLSE 211

Query: 189 KDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLKD 368
           +D  D+ FG+   VD +  SFV+ A+D+ +++  L       IKI +KIE+ E +K   +
Sbjct: 212 QDAQDLRFGVEHNVDIVFASFVRKASDVAAIRAALGPEG-RTIKIISKIENHEGVKKFDE 270

Query: 369 IIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           I+  SDG+MVARGDLG+++P  ++   Q+ ++  C    KPV
Sbjct: 271 ILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPV 312
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>KPYC_ARATH (O65595) Probable pyruvate kinase, cytosolic isozyme (EC 2.7.1.40)|
           (PK)
          Length = 497

 Score = 90.1 bits (222), Expect = 3e-18
 Identities = 51/146 (34%), Positives = 88/146 (60%), Gaps = 1/146 (0%)
 Frame = +3

Query: 60  EKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLSTKDWADI-EFGITEGVDC 236
           +K  G +RC+C +  +L  R  ++    G +V+    LPTL+ KD  DI E+G+   +D 
Sbjct: 143 DKEKGTVRCRCENTSMLGERKNVNL--PGVVVD----LPTLTEKDKQDILEWGVPNQIDM 196

Query: 237 IALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLKDIIXASDGVMVARGDLG 416
           IALSFV+  +D+  ++  L + + + I + +K+E+ E + N  DI+  SD  M+ARGDLG
Sbjct: 197 IALSFVRKGSDLVQVRKLLGKHA-KTILLMSKVENQEGVANFDDILINSDAFMIARGDLG 255

Query: 417 VQVPLXQIPXIQEAIVELCXNLNKPV 494
           +++P+ +I   Q+ ++  C  + KPV
Sbjct: 256 MEIPIEKIFLAQKVMIYKCNFMGKPV 281
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>KPYK1_CANGA (Q6FIS9) Pyruvate kinase 1 (EC 2.7.1.40) (PK 1)|
          Length = 501

 Score = 89.7 bits (221), Expect = 4e-18
 Identities = 53/165 (32%), Positives = 88/165 (53%), Gaps = 1/165 (0%)
 Frame = +3

Query: 3   ILVGDELVIDGGMATFEVTEKIGGD-LRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPT 179
           I  G  + +D G+ +FEV + +    L+ K  + G      K+   +   L   +  LP 
Sbjct: 138 ISAGRIIYVDDGVLSFEVLQVVDDKTLKVKSLNAG------KICSHKGVNLPGTDVDLPA 191

Query: 180 LSTKDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKN 359
           LS KD AD+ FG+  GV  I  SF++ A D+ +++  L     + IKI  KIE+ + + N
Sbjct: 192 LSEKDKADLRFGVENGVHMIFASFIRTAQDVLTIREVLGEDGKD-IKIVVKIENQQGVNN 250

Query: 360 LKDIIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
             +I+  +D VMVARGDLG+++P  ++  +Q+ ++       KPV
Sbjct: 251 FDEILKVTDAVMVARGDLGIEIPAPEVLAVQKKLIAKSNLAGKPV 295
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>KPYK_LEIME (Q27686) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 499

 Score = 89.7 bits (221), Expect = 4e-18
 Identities = 53/162 (32%), Positives = 87/162 (53%), Gaps = 1/162 (0%)
 Frame = +3

Query: 12  GDELVIDGGMATFEV-TEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLST 188
           G+ + ID G+   +V + +    L C  T+   +  R      R   L   +  LP +S 
Sbjct: 139 GNYIYIDDGILILQVQSHEDEQTLECTVTNSHTISDR------RGVNLPGCDVDLPAVSA 192

Query: 189 KDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLKD 368
           KD  D++FG+ +GVD I  SF++ A  +  ++  L  +  + I I  KIE+ + ++N+  
Sbjct: 193 KDRVDLQFGVEQGVDMIFASFIRSAEQVGDVRKALGPKGRD-IMIICKIENHQGVQNIDS 251

Query: 369 IIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           II  SDG+MVARGDLGV++P  ++   Q+ ++  C    KPV
Sbjct: 252 IIEESDGIMVARGDLGVEIPAEKVVVAQKILISKCNVAGKPV 293
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>KPYK2_SYNY3 (P73534) Pyruvate kinase 2 (EC 2.7.1.40) (PK 2)|
          Length = 591

 Score = 88.2 bits (217), Expect = 1e-17
 Identities = 52/163 (31%), Positives = 89/163 (54%), Gaps = 2/163 (1%)
 Frame = +3

Query: 12  GDELVIDGGMATFEVTE--KIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLS 185
           G  +++D G     V E   +  DL C+    G L     ++F   G  +     +  ++
Sbjct: 126 GARILLDDGKLEMLVEEVDTVARDLHCRVIVGGTLSSNKGVNF--PGVCLS----VKAMT 179

Query: 186 TKDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLK 365
            KD  D+ FG+ +GVD +ALSFV++  DI  +K  ++    + + + AKIE  E++K+++
Sbjct: 180 DKDKEDLMFGLDQGVDWVALSFVRNPQDIDEIKGLIAAAG-KSVPVIAKIEKHEAIKDMQ 238

Query: 366 DIIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
            ++   DGVMVARGDLGV++P   +P +Q+ ++     L  PV
Sbjct: 239 AVLEKCDGVMVARGDLGVELPAEDVPILQKKLIATANRLGIPV 281
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>KPYK_TRYBO (Q27788) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 498

 Score = 88.2 bits (217), Expect = 1e-17
 Identities = 49/162 (30%), Positives = 85/162 (52%)
 Frame = +3

Query: 9   VGDELVIDGGMATFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLST 188
           VG  + +D G+    V +  G D+ C   +   +  R  ++      L   +  LP +S 
Sbjct: 141 VGGHIFVDDGLLDLIVVKISGKDIECVAQNTHTISNRKGIN------LPNADVDLPAVSE 194

Query: 189 KDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLKD 368
           KD  D++FG    VD +  SF+++A+ +  ++     +    I + AKIE+ + + N+  
Sbjct: 195 KDLMDLQFGAKNRVDFVFASFIRNADQVNEVRQAFGGK----IAVIAKIENYQGIDNIDA 250

Query: 369 IIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           II A+DG+MVARGDLGV++P  ++   Q+ I+  C  + K V
Sbjct: 251 IIDAADGIMVARGDLGVEIPAEKVVIAQKMIMSKCNKVGKTV 292
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>KPYK_THEAC (P32044) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 544

 Score = 87.8 bits (216), Expect = 1e-17
 Identities = 53/155 (34%), Positives = 94/155 (60%)
 Frame = +3

Query: 3   ILVGDELVIDGGMATFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTL 182
           + VGD +++  G  +FEV       +R    + G+L  R++++    G+ +E    L T+
Sbjct: 102 VQVGDRILMSDGEVSFEVESTDPFTIRA--LNDGVLRDRSRVNI--PGRFIE----LGTI 153

Query: 183 STKDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNL 362
           + +D A I  GI +GVD  ALSFV+ + ++ SL+ ++     +   I +KIE+   L N+
Sbjct: 154 TDRDRAFIREGIADGVDFFALSFVQKSENVDSLRDFVIDSGGDQY-IISKIETKSGLDNI 212

Query: 363 KDIIXASDGVMVARGDLGVQVPLXQIPXIQEAIVE 467
           ++I+ +SDG+MVARGDLGV++PL ++   Q+ I++
Sbjct: 213 EEIVKSSDGIMVARGDLGVELPLKEVVLAQKHIIK 247
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>KPYC_TOBAC (Q42954) Pyruvate kinase, cytosolic isozyme (EC 2.7.1.40) (PK)|
          Length = 508

 Score = 86.7 bits (213), Expect = 3e-17
 Identities = 55/156 (35%), Positives = 89/156 (57%), Gaps = 3/156 (1%)
 Frame = +3

Query: 36  GMATFEVT--EKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLSTKDWADI- 206
           G  TF V   +K  G  RC+C +  +L  R  ++    G +V+    LPTL+ KD  DI 
Sbjct: 144 GQITFTVLSCDKENGLDRCRCENTAVLGERKNVNL--PGVIVD----LPTLTDKDKDDIL 197

Query: 207 EFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLKDIIXASD 386
            +G+   +D IALSFV+  +D+  ++  L   + ++I + +K+E+ E + N  DI+  SD
Sbjct: 198 NWGVPNHIDMIALSFVRKGSDLVEVRKLLGEHA-KNILLMSKVENQEGVANFDDILLNSD 256

Query: 387 GVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
             MVARGDLG+++P+ +I   Q+ ++  C    KPV
Sbjct: 257 AFMVARGDLGMEIPIEKIFLAQKVMIYKCNIQGKPV 292
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>KPYR_MOUSE (P53657) Pyruvate kinase isozymes R/L (EC 2.7.1.40) (L-PK)|
          Length = 574

 Score = 86.3 bits (212), Expect = 4e-17
 Identities = 55/164 (33%), Positives = 85/164 (51%)
 Frame = +3

Query: 3   ILVGDELVIDGGMATFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTL 182
           + VG  + ID G+ +  V  KIG +      + G  L   K        L      LP L
Sbjct: 211 VAVGGRIYIDDGLISL-VVRKIGPEGLVTEVEHGGFLGNRK-----GVNLPNAEVDLPGL 264

Query: 183 STKDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNL 362
           S +D  D+ FG+   VD I  SFV+ A+D+ +++  L       IKI +KIE+ E +K  
Sbjct: 265 SEQDLLDLRFGVEHYVDIIFASFVRKASDVVAVRDALGPEG-RGIKIISKIENHEGVKKF 323

Query: 363 KDIIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
            +I+  SDG+M+ARGDLG+++P  ++   Q+ ++  C    KPV
Sbjct: 324 DEILEVSDGIMMARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPV 367
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>KPYK1_AGRVI (P70789) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 474

 Score = 85.9 bits (211), Expect = 5e-17
 Identities = 55/161 (34%), Positives = 85/161 (52%)
 Frame = +3

Query: 12  GDELVIDGGMATFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLSTK 191
           GD+L+ID G             +  K    G +  R  ++    G +++    +  L+ K
Sbjct: 124 GDDLLIDDGRVRVRALGVSDEFIDAKVIVAGPISNRKGVNL--PGTVLD----ISPLTPK 177

Query: 192 DWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLKDI 371
           D  D+EFG+  GVD IALSFV+ A D+   ++ +S R+     + AKIE   +L  + DI
Sbjct: 178 DRKDLEFGLELGVDWIALSFVQTARDMIEARSLVSDRA----GLIAKIEKPSALDEIDDI 233

Query: 372 IXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           +  SD +MVARGDLGV++P   +P  Q+ ++  C    KPV
Sbjct: 234 VALSDAIMVARGDLGVEIPPEDVPGRQKELIRACRIAAKPV 274
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>KPYC_SOYBN (Q42806) Pyruvate kinase, cytosolic isozyme (EC 2.7.1.40) (PK)|
          Length = 511

 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 52/164 (31%), Positives = 94/164 (57%), Gaps = 3/164 (1%)
 Frame = +3

Query: 12  GDELVIDGGMATFEVT--EKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLS 185
           G+ ++   G  T  V   +   G +RC+C +   L  R  ++    G +V+    LPTL+
Sbjct: 139 GNTILCSDGTITLTVLSCDPDAGTVRCRCENTATLGERKNVNL--PGVVVD----LPTLT 192

Query: 186 TKDWADI-EFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNL 362
            KD  DI  +G+   +D IALSFV+  +D+ +++  L   + ++I++ +K+E+ E + N 
Sbjct: 193 EKDKEDILGWGVPNKIDMIALSFVRKGSDLVNVRKVLGPHA-KNIQLMSKVENQEGVLNF 251

Query: 363 KDIIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
            +I+  +D  MVARGDLG+++P+ +I   Q+ ++  C  + KPV
Sbjct: 252 DEILRETDAFMVARGDLGMEIPVEKIFLAQKMMIYKCNLVGKPV 295
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>KPYK_BORBU (O51323) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 477

 Score = 83.6 bits (205), Expect = 3e-16
 Identities = 52/161 (32%), Positives = 84/161 (52%)
 Frame = +3

Query: 12  GDELVIDGGMATFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLSTK 191
           G +++ID G     V  K+   L C+  + G +  + K S    G  ++    L +++ K
Sbjct: 114 GSKVLIDDGELEMTVVAKLPDRLICEIKNDGQI--KNKKSINTPGISLK----LQSVTEK 167

Query: 192 DWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLKDI 371
           D   IE      VD IA SFV+ + D+  ++  L+      +KI +KIE+ E + N+++I
Sbjct: 168 DKGFIELAAKYNVDFIAHSFVRHSKDVQDVQEILTASGNPDVKIISKIENQEGIDNIEEI 227

Query: 372 IXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
             AS G+MVARGD+GV++P   +P  Q  I + C     PV
Sbjct: 228 AKASYGIMVARGDMGVEIPAEDVPIAQLKITQTCIKYGIPV 268
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>KPYK_METJA (Q57572) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 447

 Score = 83.2 bits (204), Expect = 3e-16
 Identities = 54/162 (33%), Positives = 86/162 (53%), Gaps = 9/162 (5%)
 Frame = +3

Query: 12  GDELVIDGGMATFEVTEK---------IGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERN 164
           G  ++I+ G     V EK         +GG+++      G+ LP  ++            
Sbjct: 103 GHFILINDGKIKLRVVEKTDKIIAVVEVGGEIK---EGMGVNLPDTRIE----------- 148

Query: 165 FGLPTLSTKDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESL 344
             LP +   D  +I+F + +  + IALSFV++  D+  LK  +S    +  ++ +KIE+ 
Sbjct: 149 --LPIIDETDLKNIKFAVEKDFEYIALSFVRNKEDVKELKDIISEYKGD-CEVISKIETK 205

Query: 345 ESLKNLKDIIXASDGVMVARGDLGVQVPLXQIPXIQEAIVEL 470
           E LKN+K+I   SDGVMVARGDLGV+VP+  IP  Q+ I+ +
Sbjct: 206 EGLKNIKEIARESDGVMVARGDLGVEVPIENIPIEQKNILRI 247
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>KPYC_SOLTU (P22200) Pyruvate kinase, cytosolic isozyme (EC 2.7.1.40) (PK)|
          Length = 510

 Score = 82.4 bits (202), Expect = 6e-16
 Identities = 52/164 (31%), Positives = 92/164 (56%), Gaps = 3/164 (1%)
 Frame = +3

Query: 12  GDELVIDGGMATFEVT--EKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLS 185
           G+ ++   G  T  V   +   G +RC+C +   L  R  ++    G +V+    LPTL+
Sbjct: 138 GNTILCADGTITLTVLSCDPPSGTVRCRCENTATLGERKNVNL--PGVVVD----LPTLT 191

Query: 186 TKDWADI-EFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNL 362
            KD  DI E+G+   +D IALSFV+  +D+ +++  L   + + I++ +K+E+ E + N 
Sbjct: 192 EKDKEDILEWGVPNNIDMIALSFVRKGSDLVNVRKVLGPHA-KRIQLMSKVENQEGVINF 250

Query: 363 KDIIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
            +I+  +D  MVARGDLG+++P+ +I   Q+ ++  C    K V
Sbjct: 251 DEILRETDSFMVARGDLGMEIPVEKIFLAQKMMIYKCNLAGKAV 294
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>KPYK_EIMTE (O44006) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 531

 Score = 82.4 bits (202), Expect = 6e-16
 Identities = 52/162 (32%), Positives = 90/162 (55%), Gaps = 1/162 (0%)
 Frame = +3

Query: 12  GDELVIDGGMATFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLSTK 191
           G+ ++I  G  + EV E     +  +  +P ++  +  ++    G  V+    LP +  K
Sbjct: 175 GNTILIADGSLSVEVVECGKDYVMTRVMNPAIIGNKKNMNL--PGVKVD----LPVIGEK 228

Query: 192 DWADI-EFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLKD 368
           D  DI  FGI  G + IA SFV+ A+D+  +++ L  +   +IKI  KIE++E L N  +
Sbjct: 229 DKNDILNFGIPMGCNFIAASFVQSADDVRYIRSILGTKG-RNIKIIPKIENVEGLLNFDE 287

Query: 369 IIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           I+  +DG+M+ARGDLG+++P  ++   Q+ ++  C    KPV
Sbjct: 288 ILQEADGIMIARGDLGMEIPPEKVFLAQKMMISKCNVAGKPV 329
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>KPYK_CHLMU (Q9PK61) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 481

 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 37/95 (38%), Positives = 64/95 (67%)
 Frame = +3

Query: 171 LPTLSTKDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLES 350
           LP ++ KD  D++FG+ + +D IA SFV+   DI S++  L      ++ I AKIE+   
Sbjct: 166 LPFMTEKDITDLKFGVEQELDLIAASFVRCNEDIDSMRKVLENFGRPNMPIIAKIENHLG 225

Query: 351 LKNLKDIIXASDGVMVARGDLGVQVPLXQIPXIQE 455
           ++N ++I  ASDG+M+ARGDLG+++ + ++P +Q+
Sbjct: 226 VQNFQEIAKASDGIMIARGDLGIELSIVEVPALQK 260
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>KPYK_CHLPN (Q9Z984) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 484

 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 45/153 (29%), Positives = 83/153 (54%)
 Frame = +3

Query: 12  GDELVIDGGMATFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLSTK 191
           G +++ID G     V       L  +  + GLL     LS      +   +  LP ++ K
Sbjct: 119 GADVLIDDGYIHAVVVSSEADSLELEFMNSGLLKSHKSLS------IRGVDVALPFMTEK 172

Query: 192 DWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLKDI 371
           D AD++FG+ + +D +A SFV+   DI +++  L+      + I AKIE+   ++N   I
Sbjct: 173 DIADLKFGVEQNMDVVAASFVRYGEDIETMRKCLADLGNPKMPIIAKIENRLGVENFSKI 232

Query: 372 IXASDGVMVARGDLGVQVPLXQIPXIQEAIVEL 470
              +DG+M+ARGDLG+++ + ++P +Q+ + ++
Sbjct: 233 AKLADGIMIARGDLGIELSVVEVPNLQKMMAKV 265
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>KPYK_CHLTR (P94685) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 485

 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 37/95 (38%), Positives = 65/95 (68%)
 Frame = +3

Query: 171 LPTLSTKDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLES 350
           LP ++ KD AD++FG+ + +D IA SFV+   DI S++  L      ++ I AKIE+   
Sbjct: 166 LPFMTEKDIADLKFGVEQELDLIAASFVRCNEDIDSMRKVLESFGRPNMPIIAKIENHLG 225

Query: 351 LKNLKDIIXASDGVMVARGDLGVQVPLXQIPXIQE 455
           ++N ++I  A+DG+M+ARGDLG+++ + ++P +Q+
Sbjct: 226 VQNFQEIARAADGIMIARGDLGIELSIVEVPGLQK 260
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>KPYK_BUCAI (P57404) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 480

 Score = 76.6 bits (187), Expect = 3e-14
 Identities = 52/165 (31%), Positives = 86/165 (52%), Gaps = 3/165 (1%)
 Frame = +3

Query: 9   VGDELVIDGGMATFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLST 188
           VGD L++D G    +V +  G ++  K    G+L     ++    G   +       L+ 
Sbjct: 123 VGDVLLLDDGRIQLKVIKSTGHEILTKVVIGGILSNNKGINKLGGGLSAD------ALTE 176

Query: 189 KDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKN--- 359
           KD  DI       VD +A+SF + +ND+   +  L++    + KI AKIE  E++ N   
Sbjct: 177 KDKKDIILATEINVDYLAISFPRCSNDLKQARK-LAKEFGSNAKIIAKIERAEAVLNQNT 235

Query: 360 LKDIIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           ++DII ASD +M+ARGDLGV++   ++  IQ+ ++     LN+ V
Sbjct: 236 IEDIILASDAIMIARGDLGVEIGDSELAGIQKKLIRTARQLNRIV 280
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>KPYK2_SALTY (Q8ZNW0) Pyruvate kinase II (EC 2.7.1.40) (PK-2)|
          Length = 479

 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 56/167 (33%), Positives = 87/167 (52%), Gaps = 3/167 (1%)
 Frame = +3

Query: 3   ILVGDELVIDGGMATFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTL 182
           ++ GD L++D G    +V E  G  +  + T  G L     ++    G   E       L
Sbjct: 120 VVPGDILLLDDGRVQLKVLEVQGMKVFTEVTVGGPLSNNKGINKLGGGLSAE------AL 173

Query: 183 STKDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKN- 359
           + KD ADI+     GVD +A+SF +   D+   +  L+R +    KI AK+E  E++ + 
Sbjct: 174 TEKDKADIQTAALIGVDYLAVSFPRCGEDLNYARR-LARDAGCDAKIVAKVERAEAVCDQ 232

Query: 360 --LKDIIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
             + DII ASD VMVARGDLGV++   ++  IQ+A++     LN+ V
Sbjct: 233 NAMDDIILASDVVMVARGDLGVEIGDPELVGIQKALIRRARQLNRAV 279
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>KPYK2_ECOLI (P21599) Pyruvate kinase II (EC 2.7.1.40) (PK-2)|
          Length = 479

 Score = 70.5 bits (171), Expect = 2e-12
 Identities = 56/167 (33%), Positives = 87/167 (52%), Gaps = 3/167 (1%)
 Frame = +3

Query: 3   ILVGDELVIDGGMATFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTL 182
           ++ GD L++D G    +V E  G  +  + T  G L     ++    G   E       L
Sbjct: 120 VVPGDILLLDDGRVQLKVLEVQGMKVFTEVTVGGPLSNNKGINKLGGGLSAE------AL 173

Query: 183 STKDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKN- 359
           + KD ADI+     GVD +A+SF +   D+   +  L+R +    KI AK+E  E++ + 
Sbjct: 174 TEKDKADIKTAALIGVDYLAVSFPRCGEDLNYARR-LARDAGCDAKIVAKVERAEAVCSQ 232

Query: 360 --LKDIIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
             + DII ASD VMVARGDLGV++   ++  IQ+A++     LN+ V
Sbjct: 233 DAMDDIILASDVVMVARGDLGVEIGDPELVGIQKALIRRARQLNRAV 279
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>KPYK_HAEIN (P43924) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 477

 Score = 68.9 bits (167), Expect = 7e-12
 Identities = 51/167 (30%), Positives = 84/167 (50%), Gaps = 3/167 (1%)
 Frame = +3

Query: 3   ILVGDELVIDGGMATFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTL 182
           ++ GD L++D G    +V    G  +  + T  G L     ++    G   +       L
Sbjct: 120 VVPGDILLLDDGRVQLKVLSTDGAKVFTEVTVGGPLSNNKGINKLGGGLSAD------AL 173

Query: 183 STKDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKN- 359
           + KD ADI      GVD +A+SF + + D+   +    +  L + KI AK+E  E++ N 
Sbjct: 174 TEKDKADIITAARIGVDFLAVSFPRSSADLNYARELAQQAGL-NAKIVAKVERAETVAND 232

Query: 360 --LKDIIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
             + DII ASD +MVARGDLGV++   ++  +Q+ ++     LN+ V
Sbjct: 233 EAMDDIILASDVIMVARGDLGVEIGDPELVGVQKKLIRRSRQLNRAV 279
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>KPYK_BUCBP (Q89AI8) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 479

 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 51/163 (31%), Positives = 82/163 (50%), Gaps = 3/163 (1%)
 Frame = +3

Query: 15  DELVIDGGMATFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLSTKD 194
           D L++D G    +V   +  ++  K    G+L     ++    G           L+ KD
Sbjct: 125 DILLLDDGKIQLKVINIVDQEIFTKIIIGGVLSNNKGINKLGGG------LSARILTKKD 178

Query: 195 WADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKNLK--- 365
             DI   I  GVD +A+SF +  +D+   +    +   +  KI AKIE  E++K+LK   
Sbjct: 179 KRDIITSIDIGVDYLAVSFPRYGSDLDHARKCAVKFGSK-AKIIAKIERAEAVKDLKIID 237

Query: 366 DIIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           +II ASD +MVARGDLGV++   ++  IQ+ ++     LN+ V
Sbjct: 238 EIILASDAIMVARGDLGVEIGESELAGIQKTLIRRARQLNRVV 280
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>KPYK_BUCAP (Q8K9M3) Pyruvate kinase (EC 2.7.1.40) (PK)|
          Length = 481

 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 37/106 (34%), Positives = 64/106 (60%), Gaps = 3/106 (2%)
 Frame = +3

Query: 180 LSTKDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIKIFAKIESLESLKN 359
           L+ KD  DI       VD +A+SF + A+D+   +  L ++S  + +I AKIE  E++ +
Sbjct: 174 LTEKDKKDIILASEIDVDYLAVSFPRCADDLIKARELL-KKSGSNAQIIAKIERAEAVFD 232

Query: 360 ---LKDIIXASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNK 488
              +++II +SD +M+ARGDLGV++   ++  IQ+ ++     LNK
Sbjct: 233 QNAIENIILSSDAIMIARGDLGVEIGDAELVGIQKKLIRTARKLNK 278
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>KPYK_THELI (Q56301) Pyruvate kinase (EC 2.7.1.40) (PK) (Fragment)|
          Length = 220

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 26/100 (26%), Positives = 48/100 (48%)
 Frame = +3

Query: 12  GDELVIDGGMATFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVERNFGLPTLSTK 191
           GD + +  G     V E    ++ C   + G+L     ++      + + N  +  ++ +
Sbjct: 126 GDTIYLSDGYIMLRVEEVRENEVECVVVNGGILFSHKGIN------IPKANLPIEAITPR 179

Query: 192 DWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLE 311
           D+  IEF I  GVD I LSFV    D+  +K++L ++S +
Sbjct: 180 DFEIIEFAIEHGVDAIGLSFVGSVYDVLKVKSFLEKKSAD 219
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>KPYK1_PHOLE (O30853) Pyruvate kinase I (EC 2.7.1.40) (PK-1) (Fragment)|
          Length = 235

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 19/39 (48%), Positives = 28/39 (71%)
 Frame = +3

Query: 378 ASDGVMVARGDLGVQVPLXQIPXIQEAIVELCXNLNKPV 494
           ASDG+MVARGDLGV++P+ ++   Q+ ++E C    K V
Sbjct: 1   ASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCNRARKVV 39
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>BRIX_METKA (Q8TYC5) Probable brix-domain ribosomal biogenesis protein|
          Length = 192

 Score = 33.1 bits (74), Expect = 0.41
 Identities = 18/48 (37%), Positives = 23/48 (47%)
 Frame = +3

Query: 18  ELVIDGGMATFEVTEKIGGDLRCKCTDPGLLLPRAKLSFWRDGKLVER 161
           E +  G    F VTE  G   R    D G + PR +LSFW  G  ++R
Sbjct: 46  EALESGAEVLFYVTEAKGNPARLHVIDLGEIPPRLRLSFWLGGVKLQR 93
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>CILB_KLEPN (P17725) Citrate lyase beta chain (EC 4.1.3.6) (Citrase beta chain)|
           (Citrate (pro-3S)-lyase beta chain) (Citryl-CoA lyase
           subunit) (EC 4.1.3.34)
          Length = 289

 Score = 30.8 bits (68), Expect = 2.1
 Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 6/68 (8%)
 Frame = +3

Query: 198 ADIEFGITEGVDCIALSFVKDANDIXSLKTYLSR------RSLEHIKIFAKIESLESLKN 359
           AD+E  +  GVD + L       DI  L+ ++ R      R +   K+ A IES   + N
Sbjct: 77  ADLEAVVRAGVDMVRLPKTDSKEDIHELEAHVERIERECGREVGSTKLMAAIESALGVVN 136

Query: 360 LKDIIXAS 383
             +I  AS
Sbjct: 137 AVEIARAS 144
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>LAG3_CAEEL (Q09260) Protein lag-3 (Abnormal germ line proliferation protein 3)|
           (Abnormal cell lineage protein 3)
          Length = 490

 Score = 29.6 bits (65), Expect = 4.6
 Identities = 18/71 (25%), Positives = 30/71 (42%)
 Frame = -2

Query: 219 LCQIQCQPNPLSIM*EAQSSFQLIFRPSRMTTWLEEEANLGLCTYSADHPRSSL*LQMSP 40
           + Q+Q Q N + +M + Q   Q I +  R     +++          +H R  + LQ   
Sbjct: 339 IAQLQQQQNKMRLMQQQQQEMQRIEQQRRQQIMQQQQQQ-----QQQEHQRQQMLLQQQQ 393

Query: 39  FHHQ*QAHHQL 7
              Q Q HHQ+
Sbjct: 394 QQQQMQQHHQM 404
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>SCNA_DROME (P35500) Sodium channel protein para (Protein paralytic)|
          Length = 2131

 Score = 29.3 bits (64), Expect = 6.0
 Identities = 19/71 (26%), Positives = 41/71 (57%), Gaps = 8/71 (11%)
 Frame = +3

Query: 237 IALSFVK---DANDIXSLKTYLSRRSLEHIKIFAKIESL-----ESLKNLKDIIXASDGV 392
           IAL++V    D  ++ +L+T+   R+L+ + I   ++++     ES+KNL+D+I  +   
Sbjct: 222 IALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFS 281

Query: 393 MVARGDLGVQV 425
           +     +G+Q+
Sbjct: 282 LSVFALMGLQI 292
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>EXOC2_ARATH (Q8S3U9) Exocyst complex component 2 (Exocyst complex component Sec5)|
          Length = 1090

 Score = 29.3 bits (64), Expect = 6.0
 Identities = 20/66 (30%), Positives = 36/66 (54%), Gaps = 5/66 (7%)
 Frame = -1

Query: 349  DSRLSIFANILM-----CSNDLLER*VFRXLMSLASFTNERAIQSTPSVMPNSMSAQSFV 185
            D + S+ A+ L+     CSN+LL++ + R  ++ A F     ++STP +   + S  SF 
Sbjct: 1006 DDKQSVSADDLLALTKQCSNELLQQELERTRVNTACFAESAPLESTPPLPKATYS--SFR 1063

Query: 184  DNVGSP 167
             ++ SP
Sbjct: 1064 GSMDSP 1069
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>LYS2_CANAL (Q12572) L-aminoadipate-semialdehyde dehydrogenase large subunit (EC|
            1.2.1.31) (Alpha-aminoadipate reductase) (Alpha-AR)
          Length = 1391

 Score = 28.9 bits (63), Expect = 7.8
 Identities = 21/47 (44%), Positives = 24/47 (51%), Gaps = 2/47 (4%)
 Frame = +3

Query: 282  KTYLSRRSLEHIKIFAKIESLESLKNLKDIIXASDGVMV--ARGDLG 416
            KTY  RRS E  K  +K   LES  +LK +   S  V V  A G LG
Sbjct: 938  KTYTMRRSKELSKELSKSALLESYSSLKQLPSGSVNVFVTGATGFLG 984
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>LRC48_RAT (Q5XI54) Leucine-rich repeat-containing protein 48|
          Length = 523

 Score = 28.9 bits (63), Expect = 7.8
 Identities = 22/75 (29%), Positives = 37/75 (49%)
 Frame = +3

Query: 141 DGKLVERNFGLPTLSTKDWADIEFGITEGVDCIALSFVKDANDIXSLKTYLSRRSLEHIK 320
           +  ++ER  GL  L+   W D+ F   E ++   L  + +  D+          SL H +
Sbjct: 73  NNNIIERIEGLENLTHLVWLDLSFNNIEAIE--GLDTLVNLEDL----------SLSHNR 120

Query: 321 IFAKIESLESLKNLK 365
           I +KI+SL+ L NL+
Sbjct: 121 I-SKIDSLDPLVNLQ 134
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>HUS2_SCHPO (Q09811) ATP-dependent DNA helicase hus2/rqh1 (EC 3.6.1.-)|
          Length = 1328

 Score = 28.9 bits (63), Expect = 7.8
 Identities = 28/93 (30%), Positives = 38/93 (40%), Gaps = 3/93 (3%)
 Frame = -1

Query: 307 NDLLER*VFRXLMSLASFTNERAIQSTPSVMPNSMSAQSFVDNVG-SPKFLSTN--FPSL 137
           ND+  R        +AS +N    +  P V  N +SA S    +   PK LS N  FP L
Sbjct: 167 NDVENRIHVSSASKVASISNTS--KPNPIVSENPISATSVSIEIPIKPKELSNNLPFPRL 224

Query: 136 QNDNLARGRSKPGSVHLQRRSPPIFSVTSNVAI 38
            N+N                SP   SV+S ++I
Sbjct: 225 NNNNTNNNNDNNAIEKRDSASPTPSSVSSQISI 257


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 66,435,658
Number of Sequences: 219361
Number of extensions: 1254038
Number of successful extensions: 3544
Number of sequences better than 10.0: 87
Number of HSP's better than 10.0 without gapping: 3407
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3474
length of database: 80,573,946
effective HSP length: 104
effective length of database: 57,760,402
effective search space used: 3465624120
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
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