ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bags36j04 |
|---|---|
| Clone Library Name | barley_pub |
>S6PD_MALDO (P28475) NADP-dependent D-sorbitol-6-phosphate dehydrogenase (EC| 1.1.1.200) (Aldose-6-phosphate reductase [NADPH]) (NADP-S6PDH) Length = 310 Score = 260 bits (665), Expect = 2e-69 Identities = 120/184 (65%), Positives = 144/184 (78%) Frame = +3 Query: 3 WNSDHGHVLEACKDSXXXXXXXXXXXXXIHFPVATKHTGVGTTDSALGDDGVLDIDTTIS 182 WNSDHGHV+EACK+S +H+P+ TKH +G T S LG+D VLDID TIS Sbjct: 79 WNSDHGHVVEACKNSLEKLQIDYLDLYLVHYPMPTKHNAIGKTASLLGEDKVLDIDVTIS 138 Query: 183 LETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIKPAVNQIETHPYFQRDSLVKF 362 L+ TW ME VS+GLVRSIG+SNY++FLTRDCLAY+KIKPAV+Q ETHPYFQRDSLVKF Sbjct: 139 LQQTWEGMEKTVSLGLVRSIGLSNYELFLTRDCLAYSKIKPAVSQFETHPYFQRDSLVKF 198 Query: 363 CQKHGICVTAHTPLGGSTANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTV 542 C KHG+ TAHTPLGG+ AN + FG+VS LDDPV+ +A+KYGK+ AQ+ LRWG+QR T Sbjct: 199 CMKHGVLPTAHTPLGGAAANKDMFGSVSPLDDPVLNDVAKKYGKSVAQICLRWGIQRKTA 258 Query: 543 VIPK 554 VIPK Sbjct: 259 VIPK 262
>AK1A1_PIG (P50578) Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde| reductase) (Aldo-keto reductase family 1 member A1) Length = 324 Score = 119 bits (299), Expect = 4e-27 Identities = 67/186 (36%), Positives = 102/186 (54%), Gaps = 2/186 (1%) Frame = +3 Query: 3 WNSDHG--HVLEACKDSXXXXXXXXXXXXXIHFPVATKHTGVGTTDSALGDDGVLDIDTT 176 WN+ H V A + + +H+P A + G DG + D T Sbjct: 81 WNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFER---GDNPFPKNADGTIRYDAT 137 Query: 177 ISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIKPAVNQIETHPYFQRDSLV 356 + TW A+E LV+ GLVR++G+SN+ D L+ A ++PAV Q+E HPY ++ L+ Sbjct: 138 -HYKDTWKALEALVAKGLVRALGLSNFSSRQIDDVLSVASVRPAVLQVECHPYLAQNELI 196 Query: 357 KFCQKHGICVTAHTPLGGSTANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQRN 536 CQ G+ VTA++PLG S L++PV+++LAEKY ++PAQ++LRW +QR Sbjct: 197 AHCQARGLEVTAYSPLGSSDRAWRDPNEPVLLEEPVVQALAEKYNRSPAQILLRWQVQRK 256 Query: 537 TVVIPK 554 + IPK Sbjct: 257 VICIPK 262
>ALDR_PIG (P80276) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)| Length = 315 Score = 119 bits (299), Expect = 4e-27 Identities = 74/188 (39%), Positives = 104/188 (55%), Gaps = 4/188 (2%) Frame = +3 Query: 3 WNSDHGH--VLEACKDSXXXXXXXXXXXXXIHFPVATKHTGVGTTDSALGDDGVLDIDTT 176 W +DH V AC+ + IH+P K G L DG + D + Sbjct: 79 WCTDHEKNLVKGACQTTLRDLKLDYLDLYLIHWPTGFKP---GKDPFPLDGDGNVVPDES 135 Query: 177 ISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYA--KIKPAVNQIETHPYFQRDS 350 +ET W AME+LV GLV++IG+SN++ L K KPAVNQIE HPY ++ Sbjct: 136 DFVET-WEAMEELVDEGLVKAIGVSNFNHLQVEKILNKPGLKYKPAVNQIEVHPYLTQEK 194 Query: 351 LVKFCQKHGICVTAHTPLGGSTANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQ 530 L+++C+ GI VTA++PLG S L+DP IK++A KY KT AQ+++R+ +Q Sbjct: 195 LIEYCKSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKYNKTTAQVLIRFPMQ 254 Query: 531 RNTVVIPK 554 RN +VIPK Sbjct: 255 RNLIVIPK 262
>AK1A1_HUMAN (P14550) Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde| reductase) (Aldo-keto reductase family 1 member A1) Length = 324 Score = 119 bits (298), Expect = 6e-27 Identities = 68/186 (36%), Positives = 104/186 (55%), Gaps = 2/186 (1%) Frame = +3 Query: 3 WNSDHG--HVLEACKDSXXXXXXXXXXXXXIHFPVATKHTGVGTTDSALGDDGVLDIDTT 176 WN+ H V A + + +H+P A + G DG + D+T Sbjct: 81 WNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFER---GDNPFPKNADGTICYDST 137 Query: 177 ISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIKPAVNQIETHPYFQRDSLV 356 ET W A+E LV+ GLV+++G+SN++ D L+ A ++PAV Q+E HPY ++ L+ Sbjct: 138 HYKET-WKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELI 196 Query: 357 KFCQKHGICVTAHTPLGGSTANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQRN 536 CQ G+ VTA++PLG S L++PV+ +LAEKYG++PAQ++LRW +QR Sbjct: 197 AHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLRWQVQRK 256 Query: 537 TVVIPK 554 + IPK Sbjct: 257 VICIPK 262
>XYL1_TRIRE (Q876L8) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 324 Score = 118 bits (296), Expect = 1e-26 Identities = 71/163 (43%), Positives = 93/163 (57%), Gaps = 7/163 (4%) Frame = +3 Query: 87 IHFPVATKHTGVGTT-DSALGDDGVLDI--DTTISLETTWHAMEDLVSMGLVRSIGISNY 257 +HFP A ++ DG ++ T +L+ TW AME LV GL RSIG+SNY Sbjct: 111 VHFPAALEYVDPSVRYPPGWFYDGKSEVRWSKTTTLQQTWGAMERLVDKGLARSIGVSNY 170 Query: 258 DIFLTRDCLAYAKIKPAVNQIETHPYFQRDSLVKFCQKHGICVTAHT---PLGGSTANTE 428 D L YA+IKPA QIE HPY Q+ LV Q GI VTA++ P G + Sbjct: 171 QAQSVYDALIYARIKPATLQIEHHPYLQQPDLVSLAQTEGIVVTAYSSFGPTGFMELDMP 230 Query: 429 WFGTVS-CLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTVVIPK 554 +V+ +D PVIK+LA+K+ +TPAQ++LRW QR VIPK Sbjct: 231 RAKSVAPLMDSPVIKALADKHRRTPAQVLLRWATQRGIAVIPK 273
>AK1A1_RAT (P51635) Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde| reductase) (Aldo-keto reductase family 1 member A1) (3-DG-reducing enzyme) Length = 324 Score = 118 bits (296), Expect = 1e-26 Identities = 67/186 (36%), Positives = 103/186 (55%), Gaps = 2/186 (1%) Frame = +3 Query: 3 WNSDHG--HVLEACKDSXXXXXXXXXXXXXIHFPVATKHTGVGTTDSALGDDGVLDIDTT 176 WN+ H V A + + +H+P A + G DG + D+T Sbjct: 81 WNTKHHPEDVEPAVRKTLADLQLEYLDLYLMHWPYAFER---GDNPFPKNADGTVKYDST 137 Query: 177 ISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIKPAVNQIETHPYFQRDSLV 356 ET W A+E LV+ GLV+++G+SN+ D L+ A ++PAV Q+E HPY ++ L+ Sbjct: 138 HYKET-WKALEALVAKGLVKALGLSNFSSRQIDDVLSVASVRPAVLQVECHPYLAQNELI 196 Query: 357 KFCQKHGICVTAHTPLGGSTANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQRN 536 CQ G+ VTA++PLG S L++PV+ +LAEK+G++PAQ++LRW +QR Sbjct: 197 AHCQARGLEVTAYSPLGSSDRAWRHPDEPVLLEEPVVLALAEKHGRSPAQILLRWQVQRK 256 Query: 537 TVVIPK 554 + IPK Sbjct: 257 VICIPK 262
>ALDR_HUMAN (P15121) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)| Length = 315 Score = 117 bits (293), Expect = 2e-26 Identities = 76/187 (40%), Positives = 105/187 (56%), Gaps = 6/187 (3%) Frame = +3 Query: 12 DHGHVLEACKDSXXXXXXXXXXXXXIHFPVATKHTGVGTTDSALGDDG-VLDIDTTISLE 188 + G V AC+ + IH+P K G L + G V+ DT I Sbjct: 84 EKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKP---GKEFFPLDESGNVVPSDTNIL-- 138 Query: 189 TTWHAMEDLVSMGLVRSIGISNY-----DIFLTRDCLAYAKIKPAVNQIETHPYFQRDSL 353 TW AME+LV GLV++IGISN+ ++ L + L Y KPAVNQIE HPY ++ L Sbjct: 139 DTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKY---KPAVNQIECHPYLTQEKL 195 Query: 354 VKFCQKHGICVTAHTPLGGSTANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQR 533 +++CQ GI VTA++PLG S L+DP IK++A K+ KT AQ+++R+ +QR Sbjct: 196 IQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQR 255 Query: 534 NTVVIPK 554 N VVIPK Sbjct: 256 NLVVIPK 262
>XYL1_ASPNG (Q9P8R5) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 319 Score = 116 bits (290), Expect = 5e-26 Identities = 71/194 (36%), Positives = 100/194 (51%), Gaps = 10/194 (5%) Frame = +3 Query: 3 WNSDHG--HVLEACKDSXXXXXXXXXXXXXIHFPVATKHT--GVGTTDSALGDDGVLDID 170 WNS H V C+ +HFP++ K+ V + L+ Sbjct: 81 WNSFHDGDRVEPICRKQLADWGIDYFDLYIVHFPISLKYVDPAVRYPPGWKSEKDELEFG 140 Query: 171 TTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIKPAVNQIETHPYFQRDS 350 +++ TW AME LV L RSIGISN+ L D L YA+I+PA QIE HPY + Sbjct: 141 NA-TIQETWTAMESLVDKKLARSIGISNFSAQLVMDLLRYARIRPATLQIEHHPYLTQTR 199 Query: 351 LVKFCQKHGICVTAHTPLGGSTANTEWFGTVSCLDDP------VIKSLAEKYGKTPAQLV 512 LV++ QK G+ VTA++ G + + +D P ++KS+AEK+G+TPAQ++ Sbjct: 200 LVEYAQKEGLTVTAYSSFG--PLSFLELSVQNAVDSPPLFEHQLVKSIAEKHGRTPAQVL 257 Query: 513 LRWGLQRNTVVIPK 554 LRW QR VIPK Sbjct: 258 LRWATQRGIAVIPK 271
>AK1A1_MOUSE (Q9JII6) Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde| reductase) (Aldo-keto reductase family 1 member A1) Length = 324 Score = 116 bits (290), Expect = 5e-26 Identities = 66/186 (35%), Positives = 103/186 (55%), Gaps = 2/186 (1%) Frame = +3 Query: 3 WNSDHG--HVLEACKDSXXXXXXXXXXXXXIHFPVATKHTGVGTTDSALGDDGVLDIDTT 176 WN+ H V A + + +H+P A + G DG + D+T Sbjct: 81 WNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFER---GDNPFPKNADGTVRYDST 137 Query: 177 ISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIKPAVNQIETHPYFQRDSLV 356 ET W A+E LV+ GLV+++G+SN++ D L+ A ++PAV Q+E HPY ++ L+ Sbjct: 138 HYKET-WKALEVLVAKGLVKALGLSNFNSRQIDDVLSVASVRPAVLQVECHPYLAQNELI 196 Query: 357 KFCQKHGICVTAHTPLGGSTANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQRN 536 C G+ VTA++PLG S L++PV+ +LAEK+G++PAQ++LRW +QR Sbjct: 197 AHCHARGLEVTAYSPLGSSDRAWRHPDEPVLLEEPVVLALAEKHGRSPAQILLRWQVQRK 256 Query: 537 TVVIPK 554 + IPK Sbjct: 257 VICIPK 262
>ALDR_RABIT (P15122) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)| Length = 315 Score = 116 bits (290), Expect = 5e-26 Identities = 73/183 (39%), Positives = 99/183 (54%), Gaps = 2/183 (1%) Frame = +3 Query: 12 DHGHVLEACKDSXXXXXXXXXXXXXIHFPVATKHTGVGTTDSALGDDGVLDIDTTISLET 191 D V AC+ + IH+P KH A G+ V+ DT Sbjct: 84 DKSLVKGACQKTLNDLKLDYLDLYLIHWPTGFKHGSEYFPLDAAGN--VIPSDTDFL--D 139 Query: 192 TWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYA--KIKPAVNQIETHPYFQRDSLVKFC 365 TW AME LV GLV+SIG+SN++ L K KPAVNQIE HPY ++ L+++C Sbjct: 140 TWEAMEGLVDEGLVKSIGVSNFNHLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIQYC 199 Query: 366 QKHGICVTAHTPLGGSTANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTVV 545 GI VTA++PLG S L+DP IK++A+K+ KT AQ+++R+ +QRN VV Sbjct: 200 HSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIADKHKKTTAQVLIRFPMQRNLVV 259 Query: 546 IPK 554 IPK Sbjct: 260 IPK 262
>ALDR_BOVIN (P16116) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)| (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) Length = 315 Score = 116 bits (290), Expect = 5e-26 Identities = 71/183 (38%), Positives = 100/183 (54%), Gaps = 2/183 (1%) Frame = +3 Query: 12 DHGHVLEACKDSXXXXXXXXXXXXXIHFPVATKHTGVGTTDSALGDDGVLDIDTTISLET 191 D V AC+ + IH+P K G L +DG + I + Sbjct: 84 DKDLVKGACQKTLSDLKLDYLDLYLIHWPTGFKP---GKDFFPLDEDGNV-IPSEKDFVD 139 Query: 192 TWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYA--KIKPAVNQIETHPYFQRDSLVKFC 365 TW AME+LV GLV++IG+SN++ L K KPAVNQIE HPY ++ L+++C Sbjct: 140 TWTAMEELVDEGLVKAIGVSNFNHLQVEKILNKPGLKYKPAVNQIECHPYLTQEKLIQYC 199 Query: 366 QKHGICVTAHTPLGGSTANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTVV 545 GI VTA++PLG S L+DP IK++A+KY KT AQ+++R+ +QRN +V Sbjct: 200 NSKGIVVTAYSPLGSPDRPWAKPEDPSILEDPRIKAIADKYNKTTAQVLIRFPIQRNLIV 259 Query: 546 IPK 554 IPK Sbjct: 260 IPK 262
>AK1E1_MOUSE (Q9DCT1) Aldo-keto reductase family 1 member E1 (EC 1.1.1.-)| Length = 301 Score = 115 bits (289), Expect = 6e-26 Identities = 68/179 (37%), Positives = 100/179 (55%), Gaps = 2/179 (1%) Frame = +3 Query: 24 VLEACKDSXXXXXXXXXXXXXIHFPVATKHTGVGTTDSALGDDGVLDIDTTISLETTWHA 203 V AC ++ IH+P+ K G D L +G + I + S TW A Sbjct: 80 VKTACTNTLEALNLDYLDLYLIHWPMGFKP---GEKDIPLDRNGKV-IPSHTSFLDTWEA 135 Query: 204 MEDLVSMGLVRSIGISNYDIFLTRDCLAYA--KIKPAVNQIETHPYFQRDSLVKFCQKHG 377 MEDLV GLV+++G+SN++ L +++P NQIE HPY + L+ FC K Sbjct: 136 MEDLVFEGLVKNLGVSNFNHEQLERLLDKPGLRVRPITNQIECHPYLNQKKLIDFCHKRN 195 Query: 378 ICVTAHTPLGGSTANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTVVIPK 554 + VTA+ PLGGS G +DD VI+ +A+K+GK+PAQ+++R+ +QRN +VIPK Sbjct: 196 VSVTAYRPLGGSG------GGFHLMDDTVIRKIAKKHGKSPAQILIRFQIQRNLIVIPK 248
>AK1D1_MOUSE (Q8VCX1) 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.99.6)| (Delta(4)-3-ketosteroid 5-beta-reductase) (Aldo-keto reductase family 1 member D1) Length = 325 Score = 114 bits (286), Expect = 1e-25 Identities = 73/193 (37%), Positives = 104/193 (53%), Gaps = 9/193 (4%) Frame = +3 Query: 3 WNSDH--GHVLEACKDSXXXXXXXXXXXXXIHFPVATKHTGVGTTDSALGDDGVLDIDTT 176 WN++H VL A + + I P+A K G ++G + D T Sbjct: 88 WNTEHVPSMVLPALERTLKALKLDYIDLYIIELPMAFKP---GKEIYPRDENGRIIYDKT 144 Query: 177 ISLETTWHAMEDLVSMGLVRSIGISNY-----DIFLTRDCLAYAKIKPAVNQIETHPYFQ 341 +L TW A+E GLV+S+G+SN+ ++ L + L Y KP NQ+E HPYF Sbjct: 145 -NLCATWEALEACKDAGLVKSLGVSNFNRRQLELILNKPGLKY---KPVTNQVECHPYFT 200 Query: 342 RDSLVKFCQKHGICVTAHTPLGGSTANTEWFGTVS--CLDDPVIKSLAEKYGKTPAQLVL 515 + L+KFCQ+H I + AH+PL G+ N W S L+D ++ SL +KY KT AQ+VL Sbjct: 201 QTKLLKFCQQHDIVIVAHSPL-GTCRNPSWVNVSSPPLLNDELLTSLGKKYNKTQAQIVL 259 Query: 516 RWGLQRNTVVIPK 554 R+ +QR VVIPK Sbjct: 260 RFNIQRGIVVIPK 272
>XYL2_CANTR (P87039) NADPH-dependent D-xylose reductase II,III (EC 1.1.1.-)| (XR) Length = 324 Score = 112 bits (279), Expect = 9e-25 Identities = 70/193 (36%), Positives = 99/193 (51%), Gaps = 9/193 (4%) Frame = +3 Query: 3 WNSDHG--HVLEACKDSXXXXXXXXXXXXXIHFPVATKHTGVGTTDSA---LGDDGVLDI 167 WN+ H +V A + IHFP+A K + GD Sbjct: 85 WNNFHDPKNVETALNKTLSDLNLDYVDLFLIHFPIAFKFVPIEEKYPPGFYCGDGDNFHY 144 Query: 168 DTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIKPAVNQIETHPYFQRD 347 + + L TW A+E LV G ++SIGISN+ L D + A IKPAV QIE HPY Q+ Sbjct: 145 ED-VPLLDTWKALEKLVEAGKIKSIGISNFTGALIYDLIRGATIKPAVLQIEHHPYLQQP 203 Query: 348 SLVKFCQKHGICVTAHTPLGGST----ANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVL 515 L+++ QK GI +T ++ G + + T + + IKS+A+K+GK+PAQ++L Sbjct: 204 KLIEYVQKAGIAITGYSSFGPQSFLELESKRALNTPTLFEHETIKSIADKHGKSPAQVLL 263 Query: 516 RWGLQRNTVVIPK 554 RW QRN VIPK Sbjct: 264 RWATQRNIAVIPK 276
>ALDR_HORVU (P23901) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)| Length = 320 Score = 110 bits (276), Expect = 2e-24 Identities = 59/133 (44%), Positives = 80/133 (60%) Frame = +3 Query: 156 VLDIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIKPAVNQIETHPY 335 VL+ D +E W ME+LV GLV+ IG+ NY + L AKI PAV Q+E HP Sbjct: 139 VLEFD----MEGVWKEMENLVKDGLVKDIGVCNYTVTKLNRLLRSAKIPPAVCQMEMHPG 194 Query: 336 FQRDSLVKFCQKHGICVTAHTPLGGSTANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVL 515 ++ D + + C+KHGI VTA++PLG S N DPV++ +A K KTP Q+++ Sbjct: 195 WKNDKIFEACKKHGIHVTAYSPLGSSEKN--------LAHDPVVEKVANKLNKTPGQVLI 246 Query: 516 RWGLQRNTVVIPK 554 +W LQR T VIPK Sbjct: 247 KWALQRGTSVIPK 259
>ALDR_RAT (P07943) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)| Length = 315 Score = 110 bits (276), Expect = 2e-24 Identities = 72/183 (39%), Positives = 96/183 (52%), Gaps = 2/183 (1%) Frame = +3 Query: 12 DHGHVLEACKDSXXXXXXXXXXXXXIHFPVATKHTGVGTTDSALGDDGVLDIDTTISLET 191 D V AC+ + IH+P K A G+ V+ DT Sbjct: 84 DQSMVKGACQKTLSDLQLDYLDLYLIHWPTGFKPGPDYFPLDASGN--VIPSDT--DFVD 139 Query: 192 TWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYA--KIKPAVNQIETHPYFQRDSLVKFC 365 TW AME LV GLV++IG+SN++ L K KPAVNQIE HPY ++ L+++C Sbjct: 140 TWTAMEQLVDEGLVKAIGVSNFNPLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIEYC 199 Query: 366 QKHGICVTAHTPLGGSTANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTVV 545 GI VTA++PLG S L+DP IK +A KY KT AQ+++R+ +QRN VV Sbjct: 200 HCKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKEIAAKYNKTTAQVLIRFPIQRNLVV 259 Query: 546 IPK 554 IPK Sbjct: 260 IPK 262
>ALDR_MOUSE (P45376) Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase)| Length = 315 Score = 110 bits (276), Expect = 2e-24 Identities = 59/123 (47%), Positives = 79/123 (64%), Gaps = 2/123 (1%) Frame = +3 Query: 192 TWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYA--KIKPAVNQIETHPYFQRDSLVKFC 365 TW AME LV GLV++IG+SN++ L K KPAVNQIE HPY ++ L+++C Sbjct: 140 TWTAMEQLVDEGLVKTIGVSNFNPLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIEYC 199 Query: 366 QKHGICVTAHTPLGGSTANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTVV 545 GI VTA++PLG S L+DP IK++A KY KT AQ+++R+ +QRN VV Sbjct: 200 HSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKYNKTTAQVLIRFPIQRNLVV 259 Query: 546 IPK 554 IPK Sbjct: 260 IPK 262
>XYL1_CANTR (O13283) NAD(P)H-dependent D-xylose reductase I,II (EC 1.1.1.-)| (XR) Length = 324 Score = 109 bits (273), Expect = 5e-24 Identities = 69/193 (35%), Positives = 98/193 (50%), Gaps = 9/193 (4%) Frame = +3 Query: 3 WNSDHG--HVLEACKDSXXXXXXXXXXXXXIHFPVATKHTGVGTTDSA---LGDDGVLDI 167 WN+ H +V A + IHFP+A K + GD Sbjct: 85 WNNFHDPKNVETALNKTLSDLNLDYVDLFLIHFPIAFKFVPIEEKYPPGFYCGDGDNFHY 144 Query: 168 DTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIKPAVNQIETHPYFQRD 347 + + L TW A+E LV G ++SIGISN+ L D + A IKPAV QIE HPY Q+ Sbjct: 145 ED-VPLLDTWKALEKLVEAGKIKSIGISNFTGALIYDLIRGATIKPAVLQIEHHPYLQQP 203 Query: 348 SLVKFCQKHGICVTAHTPLGGST----ANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVL 515 L+++ QK GI +T ++ G + + T + + IK +A+K+GK+PAQ++L Sbjct: 204 KLIEYVQKAGIAITGYSSFGPQSFLELESKRALNTPTLFEHETIKLIADKHGKSPAQVLL 263 Query: 516 RWGLQRNTVVIPK 554 RW QRN VIPK Sbjct: 264 RWATQRNIAVIPK 276
>XYL1_PICGU (O94735) NADPH-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 317 Score = 109 bits (272), Expect = 6e-24 Identities = 74/193 (38%), Positives = 96/193 (49%), Gaps = 9/193 (4%) Frame = +3 Query: 3 WNSDHG--HVLEACKDSXXXXXXXXXXXXXIHFPVATKHTGVGTTDSA---LGDDGVLDI 167 WNS H +V +A + IHFP+A K GD Sbjct: 78 WNSFHDPKNVEKALDKTLSDLKVDYLDLFLIHFPIAFKFVPFEEKYPPGFYCGDGDKFHY 137 Query: 168 DTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIKPAVNQIETHPYFQRD 347 + + L TW A+E LV G +RSIGISN+ L +D L AKIKPAV QIE HPY Q+ Sbjct: 138 ED-VPLIDTWRALEKLVEKGKIRSIGISNFSGALIQDLLRSAKIKPAVLQIEHHPYLQQP 196 Query: 348 SLVKFCQKHGICVTAHTPLGGST----ANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVL 515 LV++ Q GI +TA++ G + + + VIKS+A K KTPAQ++L Sbjct: 197 RLVEYVQSQGIAITAYSSFGPQSFVELDHPRVKDVKPLFEHDVIKSVAGKVKKTPAQVLL 256 Query: 516 RWGLQRNTVVIPK 554 RW QR VIPK Sbjct: 257 RWATQRGLAVIPK 269
>XYL1_CANTE (O74237) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 322 Score = 108 bits (271), Expect = 8e-24 Identities = 67/192 (34%), Positives = 96/192 (50%), Gaps = 8/192 (4%) Frame = +3 Query: 3 WNSDHG--HVLEACKDSXXXXXXXXXXXXXIHFPVATKHTGVGTT--DSALGDDGVLDID 170 WN+ H +V A + IHFP+A K + DG + Sbjct: 83 WNNYHDPKNVETALNKTLADLKVDYVDLFLIHFPIAFKFVPIEEKYPPGFYCGDGNNFVY 142 Query: 171 TTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIKPAVNQIETHPYFQRDS 350 + + TW A+E LV+ G ++SIG+SN+ L D L A IKPAV Q+E HPY Q+ Sbjct: 143 EDVPILETWKALEKLVAAGKIKSIGVSNFPGALLLDLLRGATIKPAVLQVEHHPYLQQPK 202 Query: 351 LVKFCQKHGICVTAHTPLGGST----ANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVLR 518 L++F QK G+ +TA++ G + T + IK++A KY KTPA+++LR Sbjct: 203 LIEFAQKAGVTITAYSSFGPQSFVEMNQGRALNTPTLFAHDTIKAIAAKYNKTPAEVLLR 262 Query: 519 WGLQRNTVVIPK 554 W QR VIPK Sbjct: 263 WAAQRGIAVIPK 274
>AK1D1_HUMAN (P51857) 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.1.3)| (Delta(4)-3-ketosteroid 5-beta-reductase) (Aldo-keto reductase family 1 member D1) Length = 326 Score = 107 bits (267), Expect = 2e-23 Identities = 59/132 (44%), Positives = 83/132 (62%), Gaps = 7/132 (5%) Frame = +3 Query: 180 SLETTWHAMEDLVSMGLVRSIGISNY-----DIFLTRDCLAYAKIKPAVNQIETHPYFQR 344 +L TW AME GLV+S+G+SN+ ++ L + L K KP NQ+E HPYF + Sbjct: 146 NLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGL---KHKPVSNQVECHPYFTQ 202 Query: 345 DSLVKFCQKHGICVTAHTPLGGSTANTEWFGTVS--CLDDPVIKSLAEKYGKTPAQLVLR 518 L+KFCQ+H I +TA++PL G++ N W S L D ++ SL ++Y KT AQ+VLR Sbjct: 203 PKLLKFCQQHDIVITAYSPL-GTSRNPIWVNVSSPPLLKDALLNSLGKRYNKTAAQIVLR 261 Query: 519 WGLQRNTVVIPK 554 + +QR VVIPK Sbjct: 262 FNIQRGVVVIPK 273
>ALD2_MOUSE (P45377) Aldose reductase-related protein 2 (EC 1.1.1.21) (AR)| (Aldehyde reductase) (Fibroblast growth factor-regulated protein) (FR-1 protein) Length = 315 Score = 107 bits (267), Expect = 2e-23 Identities = 58/138 (42%), Positives = 83/138 (60%), Gaps = 2/138 (1%) Frame = +3 Query: 147 DDGVLDIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYA--KIKPAVNQI 320 D G + T LE W ME+LV GLV+++G+SN++ F L K KP NQ+ Sbjct: 126 DQGRILTSKTTFLEA-WEGMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPVTNQV 184 Query: 321 ETHPYFQRDSLVKFCQKHGICVTAHTPLGGSTANTEWFGTVSCLDDPVIKSLAEKYGKTP 500 E HPY ++ L+++C GI VTA++PLG + S L+DP IK +A K+ KT Sbjct: 185 ECHPYLTQEKLIQYCHSKGISVTAYSPLGSPDRPSAKPEDPSLLEDPKIKEIAAKHEKTS 244 Query: 501 AQLVLRWGLQRNTVVIPK 554 AQ+++R+ +QRN VVIPK Sbjct: 245 AQVLIRFHIQRNVVVIPK 262
>XYL1_PICST (P31867) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 318 Score = 106 bits (265), Expect = 4e-23 Identities = 69/193 (35%), Positives = 96/193 (49%), Gaps = 9/193 (4%) Frame = +3 Query: 3 WNSDH--GHVLEACKDSXXXXXXXXXXXXXIHFPVATKHTGVGTTDSA---LGDDGVLDI 167 WN+ H +V +A + IHFPV K + G D Sbjct: 79 WNNYHHPDNVEKALNRTLSDLQVDYVDLFLIHFPVTFKFVPLEEKYPPGFYCGKGDNFDY 138 Query: 168 DTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIKPAVNQIETHPYFQRD 347 + LET W A+E LV G +RSIG+SN+ L D L A IKP+V Q+E HPY Q+ Sbjct: 139 EDVPILET-WKALEKLVKAGKIRSIGVSNFPGALLLDLLRGATIKPSVLQVEHHPYLQQP 197 Query: 348 SLVKFCQKHGICVTAHTPLGGST----ANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVL 515 L++F Q GI VTA++ G + T ++ IK++A K+GK+PAQ++L Sbjct: 198 RLIEFAQSRGIAVTAYSSFGPQSFVELNQGRALNTSPLFENETIKAIAAKHGKSPAQVLL 257 Query: 516 RWGLQRNTVVIPK 554 RW QR +IPK Sbjct: 258 RWSSQRGIAIIPK 270
>XYL1_CANSH (Q9P430) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 323 Score = 106 bits (264), Expect = 5e-23 Identities = 62/162 (38%), Positives = 87/162 (53%), Gaps = 6/162 (3%) Frame = +3 Query: 87 IHFPVATKHTGVGTT--DSALGDDGVLDIDTTISLETTWHAMEDLVSMGLVRSIGISNYD 260 IHFP+A K + DG + + + TW A+E LV G +RSIG+SN+ Sbjct: 114 IHFPIAFKFVPIEEKYPPGFYCGDGDNFVYEDVPILETWKALEKLVKAGKIRSIGVSNFP 173 Query: 261 IFLTRDCLAYAKIKPAVNQIETHPYFQRDSLVKFCQKHGICVTAHTPLGGST----ANTE 428 L D A IKPAV Q+E HPY Q+ L+++ QK GI VTA++ G + Sbjct: 174 GALLLDLFRGATIKPAVLQVEHHPYLQQPKLIEYAQKVGITVTAYSSFGPQSFVEMNQGR 233 Query: 429 WFGTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTVVIPK 554 T + + VIK++A K+ K PA+++LRW QR VIPK Sbjct: 234 ALNTPTLFEHDVIKAIAAKHNKVPAEVLLRWSAQRGIAVIPK 275
>ALD2_CRIGR (O08782) Aldose reductase-related protein 2 (EC 1.1.1.21) (AR)| (Aldehyde reductase) (Aldo-keto reductase) Length = 315 Score = 105 bits (263), Expect = 7e-23 Identities = 58/140 (41%), Positives = 85/140 (60%), Gaps = 4/140 (2%) Frame = +3 Query: 147 DDGVLDIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYA--KIKPAVNQI 320 DD + + I+ W ME+LV GLV+++G+SN++ F L K KP NQ+ Sbjct: 125 DDQGNVLTSKITFLDAWEVMEELVDEGLVKALGVSNFNHFQIERILNKPGLKHKPVTNQV 184 Query: 321 ETHPYFQRDSLVKFCQKHGICVTAHTPLGGSTANTEWF--GTVSCLDDPVIKSLAEKYGK 494 E HPY ++ L+++C GI VTA++PLG + N W S L+DP IK +A K+ K Sbjct: 185 ECHPYLTQEKLIEYCHSKGITVTAYSPLG--SPNRPWAKPEDPSLLEDPKIKEIAAKHKK 242 Query: 495 TPAQLVLRWGLQRNTVVIPK 554 T AQ+++R+ +QRN VVIPK Sbjct: 243 TSAQVLIRFHIQRNVVVIPK 262
>AK1BA_HUMAN (O60218) Aldo-keto reductase family 1 member B10 (EC 1.1.1.-)| (Aldose reductase-like) (ARL-1) (Small intestine reductase) (SI reductase) (Aldose reductase-related protein) (ARP) (hARP) Length = 316 Score = 105 bits (263), Expect = 7e-23 Identities = 53/122 (43%), Positives = 76/122 (62%), Gaps = 2/122 (1%) Frame = +3 Query: 195 WHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYA--KIKPAVNQIETHPYFQRDSLVKFCQ 368 W AME+LV GLV+++G+SN+ F L K KP NQ+E HPY ++ L+++C Sbjct: 142 WEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCH 201 Query: 369 KHGICVTAHTPLGGSTANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTVVI 548 GI VTA++PLG S L+DP IK +A K+ KT AQ+++R+ +QRN +VI Sbjct: 202 SKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVI 261 Query: 549 PK 554 PK Sbjct: 262 PK 263
>AK1D1_RABIT (Q9TV64) 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.99.6)| (Delta(4)-3-ketosteroid 5-beta-reductase) (Aldo-keto reductase family 1 member D1) Length = 326 Score = 104 bits (259), Expect = 2e-22 Identities = 58/132 (43%), Positives = 81/132 (61%), Gaps = 7/132 (5%) Frame = +3 Query: 180 SLETTWHAMEDLVSMGLVRSIGISNY-----DIFLTRDCLAYAKIKPAVNQIETHPYFQR 344 +L TW A+E GLV+S+G+SN+ ++ L + L K KP NQ+E HPYF + Sbjct: 146 NLCATWEALEACKDAGLVKSLGVSNFNRQQLELLLNKPGL---KHKPVCNQVECHPYFTQ 202 Query: 345 DSLVKFCQKHGICVTAHTPLGGSTANTEWFGT--VSCLDDPVIKSLAEKYGKTPAQLVLR 518 L+KFCQ+H I + A++PL G+ N W T L D ++ SL +KY KT AQ+VLR Sbjct: 203 PKLLKFCQQHDIIIVAYSPL-GTCRNPMWVNTSLPPLLKDTLLNSLGKKYKKTAAQIVLR 261 Query: 519 WGLQRNTVVIPK 554 + +QR VVIPK Sbjct: 262 FNVQRGVVVIPK 273
>XYL1_PACTA (P78736) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 318 Score = 103 bits (257), Expect = 3e-22 Identities = 70/196 (35%), Positives = 97/196 (49%), Gaps = 12/196 (6%) Frame = +3 Query: 3 WNSDHG--HVLEACKDSXXXXXXXXXXXXXIHFPVATKHTGVGTT--DSALGDDGVLDID 170 WN+ H +V +A S +HFP++ K DG I Sbjct: 79 WNNFHAKENVKKALMKSLSDFNLDYFDLYLMHFPISFKFVPFEEKYPPGFYCGDGDKFIY 138 Query: 171 TTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIKPAVNQIETHPYFQRDS 350 + + TW AME+LV GLV+SIG+SN L D + A+IKPA QIE HPY Q++ Sbjct: 139 EDVPIIETWRAMENLVDEGLVKSIGVSNVSGGLLEDLIKAARIKPASLQIEHHPYLQQNK 198 Query: 351 LVKFCQKHGICVTAHT--------PLGGSTANTEWFGTVSCLDDPVIKSLAEKYGKTPAQ 506 LV++ Q GI VT ++ LG TA T ++ I ++A K+GKTP Q Sbjct: 199 LVEYAQLKGIVVTGYSNFGPLSFLELGNETAKK----TQPLYENKTITTIAAKHGKTPFQ 254 Query: 507 LVLRWGLQRNTVVIPK 554 ++LRW QR +IPK Sbjct: 255 VLLRWVNQRGIAIIPK 270
>ALD1_MOUSE (P21300) Aldose reductase-related protein 1 (EC 1.1.1.21) (AR)| (Aldehyde reductase) (VAS deferens androgen-dependent protein) (MVDP) (Aldo-keto reductase family 1 member B7) Length = 315 Score = 102 bits (255), Expect = 6e-22 Identities = 54/122 (44%), Positives = 77/122 (63%), Gaps = 2/122 (1%) Frame = +3 Query: 195 WHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYA--KIKPAVNQIETHPYFQRDSLVKFCQ 368 W AME+LV GLV+++GISN++ F L K KP NQIE+HPY ++ L+++CQ Sbjct: 141 WEAMEELVDQGLVKALGISNFNHFQIERLLNKPGLKHKPVTNQIESHPYLTQEKLIQYCQ 200 Query: 369 KHGICVTAHTPLGGSTANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTVVI 548 GI VTA++PLG ++ P IK +A K+ KT AQ+++R+ +QRN VVI Sbjct: 201 SKGIAVTAYSPLGSPDRPYAKPEDPVVMEIPKIKEIAAKHKKTVAQVLIRFHVQRNVVVI 260 Query: 549 PK 554 PK Sbjct: 261 PK 262
>XYL1_CANPA (Q6Y0Z3) NADH-dependent D-xylose reductase (EC 1.1.1.175) (XR)| Length = 324 Score = 102 bits (254), Expect = 7e-22 Identities = 67/193 (34%), Positives = 95/193 (49%), Gaps = 9/193 (4%) Frame = +3 Query: 3 WNSDHG--HVLEACKDSXXXXXXXXXXXXXIHFPVATKHTGVGTTDSA---LGDDGVLDI 167 WNS H +V A + IHFP+A K + GD I Sbjct: 85 WNSFHDKKNVEVALMKTLSDLNLDYVDLFYIHFPIAQKPVPIEKKYPPGFYCGDGDKWSI 144 Query: 168 DTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIKPAVNQIETHPYFQRD 347 + + L TW A+E LV GL +SIGISN+ L D + IKP QIE HPY + Sbjct: 145 EE-VPLLDTWRALEKLVDQGLAKSIGISNFSAQLIYDLIRGCTIKPVALQIEHHPYLTQP 203 Query: 348 SLVKFCQKHGICVTAHTPLGGST----ANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVL 515 LV++ Q H I +T ++ G + T L++P +KS+A+K+GK+PAQ++L Sbjct: 204 KLVEYVQLHDIQITGYSSFGPQSFLEMDLKRALDTPVLLEEPTVKSIADKHGKSPAQVLL 263 Query: 516 RWGLQRNTVVIPK 554 R+ QR VIP+ Sbjct: 264 RYQTQRGIAVIPR 276
>XYL1_KLULA (P49378) NAD(P)H-dependent D-xylose reductase (EC 1.1.1.-) (XR)| Length = 329 Score = 99.4 bits (246), Expect = 6e-21 Identities = 66/200 (33%), Positives = 94/200 (47%), Gaps = 16/200 (8%) Frame = +3 Query: 3 WNSDH--GHVLEACKDSXXXXXXXXXXXXXIHFPVATKHTG----------VGTTDSALG 146 WNS H +V A + + IHFP+A K G D A G Sbjct: 83 WNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVPFDEKYPPGFYTGKEDEAKG 142 Query: 147 DDGVLDIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIKPAVNQIET 326 + + L TW A+E LV G ++S+GISN+ L +D L A+IKP QIE Sbjct: 143 HIE----EEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQDLLRGARIKPVALQIEH 198 Query: 327 HPYFQRDSLVKFCQKHGICVTAHTPLGG----STANTEWFGTVSCLDDPVIKSLAEKYGK 494 HPY ++ L+K+ + GI V A++ G N + T + + IKS+A K+ Sbjct: 199 HPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALNTPTLFEHDTIKSIASKHKV 258 Query: 495 TPAQLVLRWGLQRNTVVIPK 554 TP Q++LRW Q +IPK Sbjct: 259 TPQQVLLRWATQNGIAIIPK 278
>DTDH_MUCMU (Q01213) 4-dihydromethyl-trisporate dehydrogenase (EC 1.1.1.-)| (4-dihydromethyl-TA dehydrogenase) Length = 321 Score = 99.4 bits (246), Expect = 6e-21 Identities = 65/192 (33%), Positives = 98/192 (51%), Gaps = 8/192 (4%) Frame = +3 Query: 3 WNSDHG--HVLEACKDSXXXXXXXXXXXXXIHFPVATKHTGVGTTDSA---LGDDGVLDI 167 WN+ H HV IHFPV ++ T +GD L Sbjct: 82 WNTFHSKKHVRALFDRQLKDTGLEYFDLYLIHFPVPLQYVDPATVYPPGWYVGDAKSLQF 141 Query: 168 DTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIKPAVNQIETHPYFQRD 347 + + + W +E +V GL R+IG++N++ D L YA+IKPAV QIE HPY ++ Sbjct: 142 EQS-PIHECWAELEKIVDAGLARNIGVANFNCQAILDLLTYARIKPAVLQIELHPYLPQE 200 Query: 348 SLVKFCQKHGICVTAHTPLGGST--ANTEWFGT-VSCLDDPVIKSLAEKYGKTPAQLVLR 518 LVK+ ++ GI +TA++ G ++ TE T S L+ +KS+A+K+ + Q++LR Sbjct: 201 RLVKWVKEQGIQITAYSSFGPTSYVDLTESGKTYTSLLEHASVKSVADKHNVSTGQVLLR 260 Query: 519 WGLQRNTVVIPK 554 W L R VIPK Sbjct: 261 WALDREFAVIPK 272
>AK1C3_PONPY (Q5R7C9) Aldo-keto reductase family 1 member C3 homolog (EC| 1.-.-.-) (Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase) (EC 1.3.1.20) (3-alpha-hydroxysteroid dehydrogenase type 2) (EC 1.1.1.213) (3-alpha-HSD type 2) (Prostaglandin F synthase) Length = 323 Score = 99.4 bits (246), Expect = 6e-21 Identities = 63/163 (38%), Positives = 92/163 (56%), Gaps = 7/163 (4%) Frame = +3 Query: 87 IHFPVATKHTGVGTTDSALGDDGVLDIDTTISLETTWHAMEDLVSMGLVRSIGISNY--- 257 IH P++ K G S ++G + D + L TTW AME+ GL +SIG+SN+ Sbjct: 116 IHSPMSLKP---GEELSPTDENGKVIFDI-VDLCTTWEAMEECKDAGLAKSIGVSNFNRR 171 Query: 258 --DIFLTRDCLAYAKIKPAVNQIETHPYFQRDSLVKFCQKHGICVTAHTPLGGSTANTEW 431 ++ L + L Y KP NQ+E HPYF R L+ FC+ I + A++ L GS + W Sbjct: 172 QLEMILNKPGLKY---KPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSAL-GSQRDKRW 227 Query: 432 FGTVS--CLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTVVIPK 554 S L+DPV+ +LA+K+ +TPA + LR+ LQR VV+ K Sbjct: 228 VDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAK 270
>AK1C4_HUMAN (P17516) Aldo-keto reductase family 1 member C4 (EC 1.1.1.-)| (Chlordecone reductase) (EC 1.1.1.225) (CDR) (3-alpha-hydroxysteroid dehydrogenase type I) (EC 1.1.1.50) (3-alpha-HSD1) (Dihydrodiol dehydrogenase 4) (DD4) (HAKRA) Length = 323 Score = 99.0 bits (245), Expect = 8e-21 Identities = 61/163 (37%), Positives = 90/163 (55%), Gaps = 7/163 (4%) Frame = +3 Query: 87 IHFPVATKHTGVGTTDSALGDDGVLDIDTTISLETTWHAMEDLVSMGLVRSIGISNY--- 257 +HFP+A K G T ++G + DT + L TW ME GL +SIG+SN+ Sbjct: 116 LHFPMALKP---GETPLPKDENGKVIFDT-VDLSATWEVMEKCKDAGLAKSIGVSNFNCR 171 Query: 258 --DIFLTRDCLAYAKIKPAVNQIETHPYFQRDSLVKFCQKHGICVTAHTPLGGSTANTEW 431 ++ L + L Y KP NQ+E HPY + L+ FC+ I + AH+ L G+ + W Sbjct: 172 QLEMILNKPGLKY---KPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSAL-GTQRHKLW 227 Query: 432 FGTVS--CLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTVVIPK 554 S L+DPV+ +LA+K+ +TPA + LR+ LQR VV+ K Sbjct: 228 VDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAK 270
>PE2R_RABIT (P80508) Prostaglandin-E(2) 9-reductase (EC 1.1.1.189)| (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) Length = 323 Score = 98.6 bits (244), Expect = 1e-20 Identities = 62/163 (38%), Positives = 90/163 (55%), Gaps = 7/163 (4%) Frame = +3 Query: 87 IHFPVATKHTGVGTTDSALGDDGVLDIDTTISLETTWHAMEDLVSMGLVRSIGISNY--- 257 IHFP A K GV + + D T+ + TW AME GL +SIG+SN+ Sbjct: 116 IHFPTALK-PGVEIIPTDEHGKAIFD---TVDICATWEAMEKCKDAGLAKSIGVSNFNRR 171 Query: 258 --DIFLTRDCLAYAKIKPAVNQIETHPYFQRDSLVKFCQKHGICVTAHTPLGGSTANTEW 431 ++ L + L Y KP NQ+E HPY + L++FC+ GI + A++ L GS EW Sbjct: 172 QLEMILNKPGLKY---KPVCNQVECHPYLNQGKLLEFCKSKGIVLVAYSAL-GSHREPEW 227 Query: 432 FGTVS--CLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTVVIPK 554 + L+DP+I +LA+K+ +TPA + LR+ LQR VV+ K Sbjct: 228 VDQSAPVLLEDPLIGALAKKHQQTPALIALRYQLQRGIVVLAK 270
>AK1C3_HUMAN (P42330) Aldo-keto reductase family 1 member C3 (EC 1.-.-.-)| (Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase) (EC 1.3.1.20) (3-alpha-hydroxysteroid dehydrogenase type 2) (EC 1.1.1.213) (3-alpha-HSD type 2) (3-alpha-HSD type II, brain) (Prost Length = 323 Score = 98.2 bits (243), Expect = 1e-20 Identities = 63/163 (38%), Positives = 91/163 (55%), Gaps = 7/163 (4%) Frame = +3 Query: 87 IHFPVATKHTGVGTTDSALGDDGVLDIDTTISLETTWHAMEDLVSMGLVRSIGISNY--- 257 IH P++ K G S ++G + D + L TTW AME GL +SIG+SN+ Sbjct: 116 IHSPMSLKP---GEELSPTDENGKVIFDI-VDLCTTWEAMEKCKDAGLAKSIGVSNFNRR 171 Query: 258 --DIFLTRDCLAYAKIKPAVNQIETHPYFQRDSLVKFCQKHGICVTAHTPLGGSTANTEW 431 ++ L + L Y KP NQ+E HPYF R L+ FC+ I + A++ L GS + W Sbjct: 172 QLEMILNKPGLKY---KPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSAL-GSQRDKRW 227 Query: 432 FGTVS--CLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTVVIPK 554 S L+DPV+ +LA+K+ +TPA + LR+ LQR VV+ K Sbjct: 228 VDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAK 270
>AK1C2_HUMAN (P52895) Aldo-keto reductase family 1 member C2 (EC 1.-.-.-)| (Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase) (EC 1.3.1.20) (Type III 3-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.213) (3-alpha-HSD3) (Chlordecone reductase homolog HAKRD) ( Length = 323 Score = 97.4 bits (241), Expect = 2e-20 Identities = 63/163 (38%), Positives = 90/163 (55%), Gaps = 7/163 (4%) Frame = +3 Query: 87 IHFPVATKHTGVGTTDSALGDDGVLDIDTTISLETTWHAMEDLVSMGLVRSIGISNY--- 257 IHFPV+ K G ++G + DT + L TW AME GL +SIG+SN+ Sbjct: 116 IHFPVSVKP---GEEVIPKDENGKILFDT-VDLCATWEAMEKCKDAGLAKSIGVSNFNHR 171 Query: 258 --DIFLTRDCLAYAKIKPAVNQIETHPYFQRDSLVKFCQKHGICVTAHTPLGGSTANTEW 431 ++ L + L Y KP NQ+E HPYF + L+ FC+ I + A++ L GS W Sbjct: 172 LLEMILNKPGLKY---KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSAL-GSHREEPW 227 Query: 432 FGTVS--CLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTVVIPK 554 S L+DPV+ +LA+K+ +TPA + LR+ LQR VV+ K Sbjct: 228 VDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAK 270
>AK1C1_PONPY (Q5REQ0) Aldo-keto reductase family 1 member C1 homolog (EC| 1.-.-.-) (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) Length = 323 Score = 97.4 bits (241), Expect = 2e-20 Identities = 62/163 (38%), Positives = 91/163 (55%), Gaps = 7/163 (4%) Frame = +3 Query: 87 IHFPVATKHTGVGTTDSALGDDGVLDIDTTISLETTWHAMEDLVSMGLVRSIGISNY--- 257 +HFPV+ K G ++G + DT + L TW AME GL +SIG+SN+ Sbjct: 116 VHFPVSVKP---GEEVIPKDENGKILFDT-VDLCATWEAMEKCKDAGLAKSIGVSNFNRR 171 Query: 258 --DIFLTRDCLAYAKIKPAVNQIETHPYFQRDSLVKFCQKHGICVTAHTPLGGSTANTEW 431 ++ L + L Y KP NQ+E HPYF + L+ FC+ I + A++ L GS +W Sbjct: 172 QLEMILNKPGLKY---KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSAL-GSHREEKW 227 Query: 432 FGTVS--CLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTVVIPK 554 S L+DPV+ +LA+K+ +TPA + LR+ LQR VV+ K Sbjct: 228 VDPNSPVLLEDPVLCALAKKHKQTPALIALRYQLQRGVVVLAK 270
>ALDX_SPOSA (P27800) Aldehyde reductase 1 (EC 1.1.1.2) (Aldehyde reductase I)| (Alcohol dehydrogenase [NADP+]) (ALR) Length = 322 Score = 97.1 bits (240), Expect = 3e-20 Identities = 62/187 (33%), Positives = 92/187 (49%), Gaps = 3/187 (1%) Frame = +3 Query: 3 WNSDHG--HVLEACKDSXXXXXXXXXXXXXIHFPVATKHTGVGTTDS-ALGDDGVLDIDT 173 WN+ H V A D+ IH+PVA G T + +D + +D Sbjct: 75 WNNSHRPEQVEPALDDTLKELGLEYLDLYLIHWPVAFPPEGDITQNLFPKANDKEVKLDL 134 Query: 174 TISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIKPAVNQIETHPYFQRDSL 353 +SL TW AM L+ G V++IG+SN+D + + + P+VNQIE HP + L Sbjct: 135 EVSLVDTWKAMVKLLDTGKVKAIGVSNFDAKMVDAIIEATGVTPSVNQIERHPLLLQPEL 194 Query: 354 VKFCQKHGICVTAHTPLGGSTANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQR 533 + + I +TA++PLG +T G + P IK +AEK G TPAQ+++ W + Sbjct: 195 IAHHKAKNIHITAYSPLGNNTV-----GAPLLVQHPEIKRIAEKNGCTPAQVLIAWAIVG 249 Query: 534 NTVVIPK 554 VIPK Sbjct: 250 GHSVIPK 256
>AK1A1_CRIGR (O70473) Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde| reductase) (Aldo-keto reductase family 1 member A1) (Fragment) Length = 228 Score = 96.3 bits (238), Expect = 5e-20 Identities = 57/166 (34%), Positives = 89/166 (53%), Gaps = 2/166 (1%) Frame = +3 Query: 3 WNSDHG--HVLEACKDSXXXXXXXXXXXXXIHFPVATKHTGVGTTDSALGDDGVLDIDTT 176 WN+ H V A + + +H+P A + G DDG + D+T Sbjct: 67 WNTKHHPEDVEAALRKTLADLQLEYLDLYLMHWPYAFER---GDNPFPKNDDGTIRYDST 123 Query: 177 ISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIKPAVNQIETHPYFQRDSLV 356 ET W A+E LV+ GLV+++G+SN++ D L+ A ++PAV Q+E HPY ++ L+ Sbjct: 124 HYKET-WKALEALVAKGLVKALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELI 182 Query: 357 KFCQKHGICVTAHTPLGGSTANTEWFGTVSCLDDPVIKSLAEKYGK 494 CQ G+ VTA++PLG S L++PV+ +LAEK+G+ Sbjct: 183 AHCQARGLEVTAYSPLGSSDRAWRHPDEPVLLEEPVVLALAEKHGR 228
>GRE3_YEAST (P38715) NADPH-dependent aldose reductase GRE3 (EC 1.1.1.21)| (NADPH-dependent aldo-keto reductase GRE3) (NADPH-dependent methylglyoxal reductase GRE3) (EC 1.1.1.-) (Xylose reductase) (EC 1.1.1.-) (Genes de respuesta a estres protein 3) Length = 327 Score = 96.3 bits (238), Expect = 5e-20 Identities = 66/205 (32%), Positives = 99/205 (48%), Gaps = 21/205 (10%) Frame = +3 Query: 3 WNSDH--GHVLEACKDSXXXXXXXXXXXXXIHFPVATKHTG----------VGTTDSALG 146 WN+ H HV A K + IHFP+A K+ G D G Sbjct: 80 WNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFKYVPFEEKYPPGFYTGADDEKKG 139 Query: 147 DDGVLDIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIKPAVNQIET 326 + + + T+ A+E+ V GL++SIG+SN+ L +D L +IKP QIE Sbjct: 140 HI----TEAHVPIIDTYRALEECVDEGLIKSIGVSNFQGSLIQDLLRGCRIKPVALQIEH 195 Query: 327 HPYFQRDSLVKFCQKHGICVTAHTPLGGST--------ANTEWFGTVSCLDDPVIKSLAE 482 HPY ++ LV+FC+ H I V A++ G + A T T + ++ VIK +++ Sbjct: 196 HPYLTQEHLVEFCKLHDIQVVAYSSFGPQSFIEMDLQLAKT----TPTLFENDVIKKVSQ 251 Query: 483 KY-GKTPAQLVLRWGLQRNTVVIPK 554 + G T +Q++LRW QR VIPK Sbjct: 252 NHPGSTTSQVLLRWATQRGIAVIPK 276
>DHB5_MOUSE (P70694) Estradiol 17 beta-dehydrogenase 5 (EC 1.1.1.-)| (17-beta-HSD 5) Length = 323 Score = 96.3 bits (238), Expect = 5e-20 Identities = 61/160 (38%), Positives = 86/160 (53%), Gaps = 4/160 (2%) Frame = +3 Query: 87 IHFPVATKHTGVGTTDSALGDDGVLDIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIF 266 IHFP+A K G ++G L D + + TW AME GL +SIG+SN++ Sbjct: 116 IHFPMAMKP---GENYLPKDENGKLIYDA-VDICDTWEAMEKCKDAGLAKSIGVSNFNRR 171 Query: 267 LTRDCLAYA--KIKPAVNQIETHPYFQRDSLVKFCQKHGICVTAHTPLGGSTANTEWFGT 440 L K KP NQ+E HPY + L+ FC+ I + A++ LG S +W Sbjct: 172 QLEKILKKPGLKYKPVCNQVECHPYLNQGKLLDFCRSKDIVLVAYSALG-SHREKQWVDQ 230 Query: 441 VS--CLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTVVIPK 554 S LD+PV+ S+A+KY +TPA + LR+ LQR VV+ K Sbjct: 231 SSPVLLDNPVLGSMAKKYNRTPALIALRYQLQRGVVVLAK 270
>DDBX_BOVIN (P52898) Dihydrodiol dehydrogenase 3 (EC 1.-.-.-) (Prostaglandin F| synthase) Length = 323 Score = 96.3 bits (238), Expect = 5e-20 Identities = 62/163 (38%), Positives = 89/163 (54%), Gaps = 7/163 (4%) Frame = +3 Query: 87 IHFPVATKHTGVGTTDSALGDDGVLDIDTTISLETTWHAMEDLVSMGLVRSIGISNY--- 257 IHFPVA K G T ++G D+ + L TW A+E GL +SIG+SN+ Sbjct: 116 IHFPVALKP---GETLFPTDENGKPIFDS-VDLCRTWEALEKCKDAGLTKSIGVSNFNHK 171 Query: 258 --DIFLTRDCLAYAKIKPAVNQIETHPYFQRDSLVKFCQKHGICVTAHTPLGGSTANTEW 431 + L + L Y KP NQ+E HPYF + L+ FC+ H I + A+ L GS EW Sbjct: 172 QLEKILNKPGLKY---KPVCNQVECHPYFNQSKLLDFCKSHDIVLVAYGAL-GSQRLKEW 227 Query: 432 F--GTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTVVIPK 554 L+DPV+ ++A+K+ +TPA + LR+ +QR VV+ K Sbjct: 228 VNPNLPFLLEDPVLSAIAKKHRQTPALVALRYQIQRGVVVLAK 270
>AK1C1_HUMAN (Q04828) Aldo-keto reductase family 1 member C1 (EC 1.1.1.-)| (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) (Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase) (EC 1.3.1.20) (High-affinity hepatic bile acid-binding protei Length = 323 Score = 95.9 bits (237), Expect = 7e-20 Identities = 62/163 (38%), Positives = 90/163 (55%), Gaps = 7/163 (4%) Frame = +3 Query: 87 IHFPVATKHTGVGTTDSALGDDGVLDIDTTISLETTWHAMEDLVSMGLVRSIGISNY--- 257 IHFPV+ K G ++G + DT + L TW A+E GL +SIG+SN+ Sbjct: 116 IHFPVSVKP---GEEVIPKDENGKILFDT-VDLCATWEAVEKCKDAGLAKSIGVSNFNRR 171 Query: 258 --DIFLTRDCLAYAKIKPAVNQIETHPYFQRDSLVKFCQKHGICVTAHTPLGGSTANTEW 431 ++ L + L Y KP NQ+E HPYF + L+ FC+ I + A++ L GS W Sbjct: 172 QLEMILNKPGLKY---KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSAL-GSHREEPW 227 Query: 432 FGTVS--CLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTVVIPK 554 S L+DPV+ +LA+K+ +TPA + LR+ LQR VV+ K Sbjct: 228 VDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAK 270
>YPR1_YEAST (Q12458) Putative reductase 1 (EC 1.1.1.-)| Length = 312 Score = 95.9 bits (237), Expect = 7e-20 Identities = 58/163 (35%), Positives = 89/163 (54%), Gaps = 7/163 (4%) Frame = +3 Query: 87 IHFPVATKHTGVGTTDSALG----DDGVLDIDTTI-SLETTWHAMEDLVSMGLVRSIGIS 251 +H+PV K V T + L +DG +DIDT + TW M++L G +++G+S Sbjct: 111 MHWPVPLKTDRV-TDGNVLCIPTLEDGTVDIDTKEWNFIKTWELMQELPKTGKTKAVGVS 169 Query: 252 NYDIFLTRDCLAYA--KIKPAVNQIETHPYFQRDSLVKFCQKHGICVTAHTPLGGSTANT 425 N+ I ++ L K+ PA NQIE HP +D L+ FC++ GI V A++P G + A Sbjct: 170 NFSINNIKELLESPNNKVVPATNQIEIHPLLPQDELIAFCKEKGIVVEAYSPFGSANA-- 227 Query: 426 EWFGTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTVVIPK 554 L + I +A+K+G PAQL++ W +QR VV+ K Sbjct: 228 ------PLLKEQAIIDMAKKHGVEPAQLIISWSIQRGYVVLAK 264
>AK1C4_MACFU (Q95JH4) Aldo-keto reductase family 1 member C4 (EC 1.1.1.-)| (Chlordecone reductase) (EC 1.1.1.225) (CDR) (3-alpha-hydroxysteroid dehydrogenase type I) (EC 1.1.1.50) (3-alpha-HSD1) (Dihydrodiol dehydrogenase 4) (DD4) (DD-4) Length = 323 Score = 95.5 bits (236), Expect = 9e-20 Identities = 60/163 (36%), Positives = 90/163 (55%), Gaps = 7/163 (4%) Frame = +3 Query: 87 IHFPVATKHTGVGTTDSALGDDGVLDIDTTISLETTWHAMEDLVSMGLVRSIGISNY--- 257 IHFP+A K G T ++G + DT + L W AME GL +SIG+SN+ Sbjct: 116 IHFPMALKP---GETPLPKDENGKVMFDT-VDLCAIWEAMEKCKDAGLAKSIGVSNFNRR 171 Query: 258 --DIFLTRDCLAYAKIKPAVNQIETHPYFQRDSLVKFCQKHGICVTAHTPLGGSTANTEW 431 ++ L L Y KP NQ+E HPY + L+ FC+ I + AH+ L G+ + W Sbjct: 172 QLEMILNNPGLKY---KPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSAL-GTQRHKLW 227 Query: 432 F--GTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTVVIPK 554 + + L+DPV+ +LA+K+ ++PA + LR+ LQR VV+ K Sbjct: 228 VDQNSPALLEDPVLCALAKKHKRSPALIALRYQLQRGVVVLAK 270
>AK1C4_MACFA (Q95JH5) Aldo-keto reductase family 1 member C4 (EC 1.1.1.-)| (Chlordecone reductase) (EC 1.1.1.225) (CDR) (3-alpha-hydroxysteroid dehydrogenase type I) (EC 1.1.1.50) (3-alpha-HSD1) (Dihydrodiol dehydrogenase 4) (DD4) (DD-4) Length = 323 Score = 95.5 bits (236), Expect = 9e-20 Identities = 60/163 (36%), Positives = 90/163 (55%), Gaps = 7/163 (4%) Frame = +3 Query: 87 IHFPVATKHTGVGTTDSALGDDGVLDIDTTISLETTWHAMEDLVSMGLVRSIGISNY--- 257 IHFP+A K G T ++G + DT + L W AME GL +SIG+SN+ Sbjct: 116 IHFPMALKP---GETPLPKDENGKVMFDT-VDLCAIWEAMEKCKDAGLAKSIGVSNFNRR 171 Query: 258 --DIFLTRDCLAYAKIKPAVNQIETHPYFQRDSLVKFCQKHGICVTAHTPLGGSTANTEW 431 ++ L L Y KP NQ+E HPY + L+ FC+ I + AH+ L G+ + W Sbjct: 172 QLEMILNNPGLKY---KPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSAL-GTQRHKLW 227 Query: 432 F--GTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTVVIPK 554 + + L+DPV+ +LA+K+ ++PA + LR+ LQR VV+ K Sbjct: 228 VDQNSPALLEDPVLCALAKKHKRSPALIALRYQLQRGVVVLAK 270
>AK1C1_MACFU (Q95JH6) Aldo-keto reductase family 1 member C1 homolog (EC| 1.-.-.-) (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) (Dihydrodiol dehydrogenase 1) (DD-1) (DD1) Length = 323 Score = 95.1 bits (235), Expect = 1e-19 Identities = 63/163 (38%), Positives = 89/163 (54%), Gaps = 7/163 (4%) Frame = +3 Query: 87 IHFPVATKHTGVGTTDSALGDDGVLDIDTTISLETTWHAMEDLVSMGLVRSIGISNY--- 257 IHFPV+ K G ++G L DT + L TW AME GL +SIG+SN+ Sbjct: 116 IHFPVSLKP---GEELIPKDENGKLLFDT-VDLCATWEAMEKCKDAGLAKSIGVSNFNRR 171 Query: 258 --DIFLTRDCLAYAKIKPAVNQIETHPYFQRDSLVKFCQKHGICVTAHTPLGGSTANTEW 431 ++ L + L Y KP NQ+E HPY + L+ FC+ I + A++ LG S W Sbjct: 172 QLEMILNKPGLKY---KPVCNQVECHPYLNQRKLLDFCKSKDIVLVAYSALG-SHREKPW 227 Query: 432 FGTVS--CLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTVVIPK 554 S L+DPV+ +LA+K+ +TPA + LR+ LQR VV+ K Sbjct: 228 VDQNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAK 270
>AK1C1_MACFA (Q95JH7) Aldo-keto reductase family 1 member C1 homolog (EC| 1.-.-.-) (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) (Dihydrodiol dehydrogenase 1) (DD-1) (DD1) Length = 323 Score = 94.0 bits (232), Expect = 3e-19 Identities = 63/163 (38%), Positives = 88/163 (53%), Gaps = 7/163 (4%) Frame = +3 Query: 87 IHFPVATKHTGVGTTDSALGDDGVLDIDTTISLETTWHAMEDLVSMGLVRSIGISNY--- 257 IHFPV+ K G ++G L DT + L TW AME GL +SIG+SN+ Sbjct: 116 IHFPVSLKP---GEELIPKDENGKLLFDT-VDLCATWEAMEKCKDAGLAKSIGVSNFNRR 171 Query: 258 --DIFLTRDCLAYAKIKPAVNQIETHPYFQRDSLVKFCQKHGICVTAHTPLGGSTANTEW 431 ++ L + L Y KP NQ+E HPY + L+ FC+ I + A + LG S W Sbjct: 172 QLEMILNKPGLKY---KPVCNQVECHPYLNQRKLLDFCKSKDIVLVAFSALG-SHREKPW 227 Query: 432 FGTVS--CLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTVVIPK 554 S L+DPV+ +LA+K+ +TPA + LR+ LQR VV+ K Sbjct: 228 VDQNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAK 270
>GCY_YEAST (P14065) GCY protein (EC 1.1.1.-)| Length = 312 Score = 92.8 bits (229), Expect = 6e-19 Identities = 51/138 (36%), Positives = 76/138 (55%), Gaps = 3/138 (2%) Frame = +3 Query: 150 DGVLDID-TTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYA--KIKPAVNQI 320 DG +D T + TW M++L G +++G+SN+ I +D LA K+ PA NQ+ Sbjct: 135 DGSRAVDITNWNFIKTWELMQELPKTGKTKAVGVSNFSINNLKDLLASQGNKLTPAANQV 194 Query: 321 ETHPYFQRDSLVKFCQKHGICVTAHTPLGGSTANTEWFGTVSCLDDPVIKSLAEKYGKTP 500 E HP +D L+ FC+ GI V A++PLG + A L +PVI +A+K P Sbjct: 195 EIHPLLPQDELINFCKSKGIVVEAYSPLGSTDA--------PLLKEPVILEIAKKNNVQP 246 Query: 501 AQLVLRWGLQRNTVVIPK 554 +V+ W +QR VV+PK Sbjct: 247 GHVVISWHVQRGYVVLPK 264
>NADO1_ORYSA (Q7G764) Probable NAD(P)H-dependent oxidoreductase 1 (EC 1.1.1.-)| Length = 321 Score = 92.8 bits (229), Expect = 6e-19 Identities = 55/186 (29%), Positives = 97/186 (52%), Gaps = 2/186 (1%) Frame = +3 Query: 3 WNSD--HGHVLEACKDSXXXXXXXXXXXXXIHFPVATKHTGVGTTDSALGDDGVLDIDTT 176 W SD G V+ A +++ +H+PV+ G D + +L + Sbjct: 87 WCSDLHAGRVVPAARETLRNLGMDYVDLLLVHWPVSLTP---GNYDFPFPKEVILP---S 140 Query: 177 ISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIKPAVNQIETHPYFQRDSLV 356 +E W ME+ +GL R+IG+SN+ L+ A ++PAVNQ+E +P +Q+ +L Sbjct: 141 FDMEGVWRGMEECHRLGLARAIGVSNFSAKKLEQLLSLAAVRPAVNQVEVNPMWQQRTLR 200 Query: 357 KFCQKHGICVTAHTPLGGSTANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQRN 536 + C++ G+ + ++PLG T W G+ + +D V++ +A GKT AQ+ LRW ++ Sbjct: 201 EVCRREGVQLCGYSPLGAK--GTPW-GSAAVMDSGVLQEIAGAKGKTLAQICLRWLYEQG 257 Query: 537 TVVIPK 554 V++ K Sbjct: 258 DVLLVK 263
>PGFS2_BOVIN (P52897) Prostaglandin-F synthase 2 (EC 1.1.1.188) (PGF synthase 2)| (PGF 2) (Prostaglandin-D2 11 reductase 2) (PGFSII) Length = 323 Score = 91.7 bits (226), Expect = 1e-18 Identities = 58/163 (35%), Positives = 89/163 (54%), Gaps = 7/163 (4%) Frame = +3 Query: 87 IHFPVATKHTGVGTTDSALGDDGVLDIDTTISLETTWHAMEDLVSMGLVRSIGISNY--- 257 IH PV+ K G + G L D+ + L TW A+E GL +SIG+SN+ Sbjct: 116 IHSPVSLKP---GNKFVPKDESGKLIFDS-VDLCHTWEALEKCKDAGLTKSIGVSNFNHK 171 Query: 258 --DIFLTRDCLAYAKIKPAVNQIETHPYFQRDSLVKFCQKHGICVTAHTPLGGSTANTEW 431 + L + L Y KP NQ+E HPY + L++FC+ H I + A+ LG +EW Sbjct: 172 QLEKILNKPGLKY---KPVCNQVECHPYLNQSKLLEFCKSHDIVLVAYAALGAQLL-SEW 227 Query: 432 FGTVS--CLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTVVIPK 554 + + L+DPV+ ++A+K+ +TPA + LR+ +QR VV+ K Sbjct: 228 VNSNNPVLLEDPVLCAIAKKHKQTPALVALRYQVQRGVVVLAK 270
>PGFS1_BOVIN (P05980) Prostaglandin-F synthase 1 (EC 1.1.1.188) (PGF synthase 1)| (PGF 1) (Prostaglandin-D2 11 reductase 1) (PGFSI) Length = 323 Score = 91.7 bits (226), Expect = 1e-18 Identities = 58/163 (35%), Positives = 89/163 (54%), Gaps = 7/163 (4%) Frame = +3 Query: 87 IHFPVATKHTGVGTTDSALGDDGVLDIDTTISLETTWHAMEDLVSMGLVRSIGISNY--- 257 IH PV+ K G + G L D+ + L TW A+E GL +SIG+SN+ Sbjct: 116 IHSPVSLKP---GNKFVPKDESGKLIFDS-VDLCHTWEALEKCKDAGLTKSIGVSNFNHK 171 Query: 258 --DIFLTRDCLAYAKIKPAVNQIETHPYFQRDSLVKFCQKHGICVTAHTPLGGSTANTEW 431 + L + L Y KP NQ+E HPY + L++FC+ H I + A+ LG +EW Sbjct: 172 QLEKILNKPGLKY---KPVCNQVECHPYLNQSKLLEFCKSHDIVLVAYAALGAQLL-SEW 227 Query: 432 FGTVS--CLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTVVIPK 554 + + L+DPV+ ++A+K+ +TPA + LR+ +QR VV+ K Sbjct: 228 VNSNNPVLLEDPVLCAIAKKHKQTPALVALRYQVQRGVVVLAK 270
>NADO2_ORYSA (Q7G765) Probable NAD(P)H-dependent oxidoreductase 2 (EC 1.-.-.-)| Length = 322 Score = 90.9 bits (224), Expect = 2e-18 Identities = 52/186 (27%), Positives = 95/186 (51%), Gaps = 2/186 (1%) Frame = +3 Query: 3 WNSD--HGHVLEACKDSXXXXXXXXXXXXXIHFPVATKHTGVGTTDSALGDDGVLDIDTT 176 W SD G V+ A +++ +H+P G+ D + ++ Sbjct: 89 WCSDLHAGRVVPAARETLRNLGMDYVDLLLVHWPATV---APGSYDFPFPKE---EMAPA 142 Query: 177 ISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIKPAVNQIETHPYFQRDSLV 356 +E W ME+ +GL R+IG+SN+ L++A ++PA NQ+E +P +Q+ +L Sbjct: 143 FDMEGVWRGMEECHRLGLARAIGVSNFSAKKLEQLLSFAVVRPAANQVEMNPMWQQRTLR 202 Query: 357 KFCQKHGICVTAHTPLGGSTANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQRN 536 + C++ G+ + ++PLG T W G+ + +D V+ +A+ GKT AQ+ LRW ++ Sbjct: 203 EVCRREGVQLCGYSPLGAK--GTPW-GSAAVMDSGVLHDIAQTKGKTLAQICLRWMYEQG 259 Query: 537 TVVIPK 554 V++ K Sbjct: 260 DVLLVK 265
>P100_LEIMA (P22045) Probable reductase (EC 1.1.-.-)| Length = 284 Score = 90.5 bits (223), Expect = 3e-18 Identities = 58/186 (31%), Positives = 84/186 (45%), Gaps = 2/186 (1%) Frame = +3 Query: 3 WNSDHGH--VLEACKDSXXXXXXXXXXXXXIHFPVATKHTGVGTTDSALGDDGVLDIDTT 176 WN++ G+ L A ++S IH+P L +G +D+ Sbjct: 81 WNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWPRGK---------DILSKEGKKYLDS- 130 Query: 177 ISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIKPAVNQIETHPYFQRDSLV 356 W A E L VR+IG+SN+ I D LA + P VNQ+E HP + L Sbjct: 131 ------WRAFEQLYKEKKVRAIGVSNFHIHHLEDVLAMCTVTPMVNQVELHPLNNQADLR 184 Query: 357 KFCQKHGICVTAHTPLGGSTANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQRN 536 FC I V A +PLG L +P++ ++ KY KT AQ++LRW +Q+N Sbjct: 185 AFCDAKQIKVEAWSPLGQG----------KLLSNPILSAIGAKYNKTAAQVILRWNIQKN 234 Query: 537 TVVIPK 554 + IPK Sbjct: 235 LITIPK 240
>DKGA_ECO57 (Q8XBT6) 2,5-diketo-D-gluconic acid reductase A (EC 1.1.1.274)| (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (AKR5C) Length = 275 Score = 89.7 bits (221), Expect = 5e-18 Identities = 59/184 (32%), Positives = 79/184 (42%) Frame = +3 Query: 3 WNSDHGHVLEACKDSXXXXXXXXXXXXXIHFPVATKHTGVGTTDSALGDDGVLDIDTTIS 182 WN DH EA DS +H+PV ID + Sbjct: 78 WNDDHNRPREALLDSLKKLQLDYIDLYLMHWPVPA-------------------IDHYVE 118 Query: 183 LETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIKPAVNQIETHPYFQRDSLVKF 362 W M +L GL++SIG+ N+ I + + + P +NQIE HP Q+ L + Sbjct: 119 ---AWKGMIELQKEGLIKSIGVCNFQIHHLQRLIDETGVTPVINQIELHPLMQQRQLHAW 175 Query: 363 CQKHGICVTAHTPLGGSTANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTV 542 H I + +PL G D VI+ LA+KYGKTPAQ+V+RW L V Sbjct: 176 NATHKIQTESWSPLAQ--------GGKGVFDQKVIRDLADKYGKTPAQIVIRWHLDSGLV 227 Query: 543 VIPK 554 VIPK Sbjct: 228 VIPK 231
>DKGA_ECOLI (Q46857) 2,5-diketo-D-gluconic acid reductase A (EC 1.1.1.274)| (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (AKR5C) Length = 275 Score = 89.0 bits (219), Expect = 8e-18 Identities = 59/184 (32%), Positives = 79/184 (42%) Frame = +3 Query: 3 WNSDHGHVLEACKDSXXXXXXXXXXXXXIHFPVATKHTGVGTTDSALGDDGVLDIDTTIS 182 WN DH EA DS +H+PV ID + Sbjct: 78 WNDDHKRPREALLDSLKKLQLDYIDLYLMHWPVPA-------------------IDHYVE 118 Query: 183 LETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIKPAVNQIETHPYFQRDSLVKF 362 W M +L GL++SIG+ N+ I + + + P +NQIE HP Q+ L + Sbjct: 119 ---AWKGMIELQKEGLIKSIGVCNFQIHHLQRLIDETGVTPVINQIELHPLMQQRQLHAW 175 Query: 363 CQKHGICVTAHTPLGGSTANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTV 542 H I + +PL G D VI+ LA+KYGKTPAQ+V+RW L V Sbjct: 176 NATHKIQTESWSPLAQ--------GGKGVFDQKVIRDLADKYGKTPAQIVIRWHLDSGLV 227 Query: 543 VIPK 554 VIPK Sbjct: 228 VIPK 231
>6DCS_SOYBN (P26690) NAD(P)H dependent 6'-deoxychalcone synthase (EC 2.3.1.170)| Length = 315 Score = 88.6 bits (218), Expect = 1e-17 Identities = 53/182 (29%), Positives = 99/182 (54%), Gaps = 1/182 (0%) Frame = +3 Query: 12 DHGH-VLEACKDSXXXXXXXXXXXXXIHFPVATKHTGVGTTDSALGDDGVLDIDTTISLE 188 +H H VL A + S IH+P++++ G + + +L D ++ Sbjct: 94 NHPHLVLPALRKSLKTLQLEYLDLYLIHWPLSSQP---GKFSFPIEVEDLLPFD----VK 146 Query: 189 TTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIKPAVNQIETHPYFQRDSLVKFCQ 368 W +ME+ +GL ++IG+SN+ + ++ L+ A I+P V+Q+E + +Q+ L +FC+ Sbjct: 147 GVWESMEECQKLGLTKAIGVSNFSVKKLQNLLSVATIRPVVDQVEMNLAWQQKKLREFCK 206 Query: 369 KHGICVTAHTPLGGSTANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTVVI 548 ++GI VTA +PL + G +++ V+K +AE +GK+ AQ+ LRW ++ + Sbjct: 207 ENGIIVTAFSPLRKGASR----GPNEVMENDVLKEIAEAHGKSIAQVSLRWLYEQGVTFV 262 Query: 549 PK 554 PK Sbjct: 263 PK 264
>YOF5_CAEEL (Q09632) Probable oxidoreductase ZK1290.5 in chromosome II (EC| 1.-.-.-) Length = 321 Score = 88.6 bits (218), Expect = 1e-17 Identities = 47/123 (38%), Positives = 64/123 (52%) Frame = +3 Query: 186 ETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIKPAVNQIETHPYFQRDSLVKFC 365 E TW ME L VRSIG+SNY I + L +A I P NQ+E HP+F + L +C Sbjct: 122 EKTWRQMELLYEDEHVRSIGVSNYSIEDLDELLEFASILPHANQVELHPWFHQADLKNYC 181 Query: 366 QKHGICVTAHTPLGGSTANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTVV 545 + GI + PL L+D + +A KY K+PAQ+ LRW +Q+N Sbjct: 182 DELGILTMGYCPLAKG----------KYLEDETLCKIASKYQKSPAQICLRWSIQQNVPT 231 Query: 546 IPK 554 +PK Sbjct: 232 VPK 234
>AKC1H_MOUSE (Q8K023) Aldo-keto reductase family 1 member C18 (EC 1.1.-.-)| (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) Length = 323 Score = 85.5 bits (210), Expect = 9e-17 Identities = 59/164 (35%), Positives = 86/164 (52%), Gaps = 8/164 (4%) Frame = +3 Query: 87 IHFPVATKHTGVGTTDSALGDDGVLDIDTTISLETTWHAMEDLVSMGLVRSIGISNY--- 257 IHFPV+ K G + G L DT + L TW AME GL +SIG+SN+ Sbjct: 116 IHFPVSLKP---GNELLPKDEHGNLIFDT-VDLCDTWEAMEKCKDAGLAKSIGVSNFNRR 171 Query: 258 --DIFLTRDCLAYAKIKPAVNQIETHPYFQRDSLVKFCQKHGICVTAHTPLGGSTANTEW 431 ++ L + L Y KP NQ+E H Y + L+ +C+ + I + A+ LG T ++ Sbjct: 172 QLEMILNKPGLKY---KPVCNQVECHLYLNQSKLLAYCKMNDIVLVAYGALG--TQRYKY 226 Query: 432 F---GTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTVVIPK 554 T LDDPV+ ++A+KY +TPA + LR+ L R V + K Sbjct: 227 CINEDTPVLLDDPVLCAMAKKYKRTPALIALRYQLDRGIVALAK 270
>YDG7_SCHPO (Q10494) Probable oxidoreductase C26F1.07 in chromosome I (EC| 1.-.-.-) Length = 321 Score = 84.7 bits (208), Expect = 2e-16 Identities = 57/159 (35%), Positives = 85/159 (53%), Gaps = 3/159 (1%) Frame = +3 Query: 87 IHFPVATKHTGVGTTDSALGDDGVLDIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIF 266 IH+PV+ K G DG L + +E TW AME L+ G VR IG+SN++ Sbjct: 117 IHWPVSFK---TGEDKFPKDKDGNLIYEKN-PIEETWKAMEKLLETGKVRHIGLSNFNDT 172 Query: 267 LTRDCLAYAKIKPAVNQIETHPYFQRDSLVKFCQKHGICVTAHTPLGGSTANTEWFGTV- 443 L AK+KPAV+Q+E HP+ + V+ +K GI VTA++P G NT + + Sbjct: 173 NLERILKVAKVKPAVHQMELHPFLPQTEFVEKHKKLGIHVTAYSPFGNQ--NTIYESKIP 230 Query: 444 SCLDDPVIKSLAEKYGK--TPAQLVLRWGLQRNTVVIPK 554 ++ I+ +A+ G+ T A + + W + R T VIPK Sbjct: 231 KLIEHETIQKIAKSKGEGVTGATIAVSWAITRGTSVIPK 269
>AK1D1_RAT (P31210) 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.99.6)| (Delta(4)-3-ketosteroid 5-beta-reductase) (Aldo-keto reductase family 1 member D1) Length = 326 Score = 84.7 bits (208), Expect = 2e-16 Identities = 52/133 (39%), Positives = 75/133 (56%), Gaps = 8/133 (6%) Frame = +3 Query: 180 SLETTWHAMEDLVSMGLVRSIGISNY-----DIFLTRDCLAYAKIKPAVNQIETHPYFQR 344 +L TW A+E GLV+S+G+SN+ ++ L + L Y KP NQ+E HPYF + Sbjct: 145 NLCATWEALEACKDAGLVKSLGVSNFNRRQLEVILNKPGLKY---KPVTNQVECHPYFTQ 201 Query: 345 DSLVKFCQKHGIC-VTAHTPLGGSTANTEWFGTVS--CLDDPVIKSLAEKYGKTPAQLVL 515 L++ + A++PLG + N W S L D ++ SL +KY KT AQ+VL Sbjct: 202 TKLLEVSASSMTSFIVAYSPLG-TCRNPLWVNVSSPPLLKDELLTSLGKKYNKTQAQIVL 260 Query: 516 RWGLQRNTVVIPK 554 R+ +QR VVIPK Sbjct: 261 RFDIQRGLVVIPK 273
>DKGB_CORSS (P15339) 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274)| (2,5-DKG reductase B) (2,5-DKGR B) (25DKGR-B) (AKR5D) Length = 276 Score = 84.3 bits (207), Expect = 2e-16 Identities = 46/121 (38%), Positives = 66/121 (54%) Frame = +3 Query: 192 TWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIKPAVNQIETHPYFQRDSLVKFCQK 371 TW M D GLVRSIG+SN+ + + + + PAVNQ+E HPYF + +L F + Sbjct: 120 TWRGMIDAREAGLVRSIGVSNFTEPMLKTLIDETGVTPAVNQVELHPYFPQAALRAFHDE 179 Query: 372 HGICVTAHTPLGGSTANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTVVIP 551 HGI + +PL + L + +++ LA YG TP Q+VLRW +Q + IP Sbjct: 180 HGIRTESWSPLARRS---------ELLTEQLLQELAVVYGVTPTQVVLRWHVQLGSTPIP 230 Query: 552 K 554 K Sbjct: 231 K 231
>MORA_PSEPU (Q02198) Morphine 6-dehydrogenase (EC 1.1.1.218) (Naloxone| reductase) Length = 295 Score = 84.3 bits (207), Expect = 2e-16 Identities = 46/124 (37%), Positives = 72/124 (58%), Gaps = 3/124 (2%) Frame = +3 Query: 192 TWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIKPAVNQIETHPYFQRDSLVKFCQK 371 +W A E ++ G R+IG+ N+ + +A + + PAVNQIE HPYF + L+ + Sbjct: 121 SWKAAEKILGDGRARAIGVCNFLEDQLDELIAASDVVPAVNQIELHPYFAQKPLLAKNRA 180 Query: 372 HGICVTAHTPLGGSTANTE---WFGTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTV 542 GI A +P+GG+ + + G L DPVI ++AE +G++ AQ++LRW Q + V Sbjct: 181 LGIVTEAWSPIGGAINDGDGDNHGGRKHPLTDPVITTIAEAHGRSAAQVILRWHFQNDVV 240 Query: 543 VIPK 554 IPK Sbjct: 241 AIPK 244
>DIDH_RAT (P23457) 3-alpha-hydroxysteroid dehydrogenase (EC 1.1.1.213)| (3-alpha-HSD) (Hydroxyprostaglandin dehydrogenase) Length = 322 Score = 83.6 bits (205), Expect = 4e-16 Identities = 56/159 (35%), Positives = 83/159 (52%), Gaps = 7/159 (4%) Frame = +3 Query: 87 IHFPVATKHTGVGTTDSALGDDGVLDIDTTISLETTWHAMEDLVSMGLVRSIGISNYDI- 263 IHFP+A + G + G L +T + + TW AME GL +SIG+SN++ Sbjct: 116 IHFPMALQP---GDIFFPRDEHGKLLFET-VDICDTWEAMEKCKDAGLAKSIGVSNFNCR 171 Query: 264 ----FLTRDCLAYAKIKPAVNQIETHPYFQRDSLVKFCQKHGICVTAHTPLGGSTANTEW 431 L + L Y KP NQ+E H Y + ++ +C+ I + ++ LG S T W Sbjct: 172 QLERILNKPGLKY---KPVCNQVECHLYLNQSKMLDYCKSKDIILVSYCTLGSSRDKT-W 227 Query: 432 FGTVS--CLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTV 542 S LDDPV+ ++A+KY +TPA + LR+ LQR V Sbjct: 228 VDQKSPVLLDDPVLCAIAKKYKQTPALVALRYQLQRGVV 266
>DKGA_SALTY (Q8ZM06) 2,5-diketo-D-gluconic acid reductase A (EC 1.1.1.274)| (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (AKR5C) Length = 275 Score = 83.6 bits (205), Expect = 4e-16 Identities = 58/184 (31%), Positives = 78/184 (42%) Frame = +3 Query: 3 WNSDHGHVLEACKDSXXXXXXXXXXXXXIHFPVATKHTGVGTTDSALGDDGVLDIDTTIS 182 WN D EA ++S +H+PV ID + Sbjct: 78 WNDDQKRPREALQESLKKLQLDYLDLYLMHWPVPA-------------------IDHYVD 118 Query: 183 LETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIKPAVNQIETHPYFQRDSLVKF 362 W M L GLV+SIG+ N+ I + + + P +NQIE HP Q+ L + Sbjct: 119 ---AWKGMIALQKEGLVKSIGVCNFQIHHLQRLIDETGVTPVINQIELHPLMQQRQLHAW 175 Query: 363 CQKHGICVTAHTPLGGSTANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTV 542 H I + +PL G D VI+ LA+KYGKTPAQ+V+RW L V Sbjct: 176 NATHKIQTESWSPLAQ--------GGEGVFDQKVIRELADKYGKTPAQIVIRWHLDCGLV 227 Query: 543 VIPK 554 VIPK Sbjct: 228 VIPK 231
>AKC1H_RAT (P51652) Aldo-keto reductase family 1 member C18 (EC 1.1.-.-)| (20-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) (HSD1) Length = 323 Score = 83.2 bits (204), Expect = 5e-16 Identities = 58/163 (35%), Positives = 86/163 (52%), Gaps = 7/163 (4%) Frame = +3 Query: 87 IHFPVATKHTGVGTTDSALGDD--GVLDIDTTISLETTWHAMEDLVSMGLVRSIGISNYD 260 IHFPV+ K D L D G L +DT + L TW AME GL +SIG+SN++ Sbjct: 116 IHFPVSLK-----PGDELLPQDEHGNLILDT-VDLCDTWEAMEKCKDAGLAKSIGVSNFN 169 Query: 261 IFLTRDCLAYAKIK--PAVNQIETHPYFQRDSLVKFCQKHGICVTAHTPLGGSTANTEWF 434 L +K P NQ+E H Y + L+ +C+ + I + A+ LG T ++ Sbjct: 170 RRQLEKILNKPGLKHRPVCNQVECHLYLNQSKLLAYCKMNDIVLVAYGALG--TQRYKYC 227 Query: 435 ---GTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTVVIPK 554 T LDDP++ ++A+KY +TPA + LR+ L+R V + K Sbjct: 228 INEDTPVLLDDPILCTMAKKYKRTPALIALRYQLERGIVTLVK 270
>DKGA_SALTI (P58744) 2,5-diketo-D-gluconic acid reductase A (EC 1.1.1.274)| (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (AKR5C) Length = 275 Score = 82.8 bits (203), Expect = 6e-16 Identities = 58/184 (31%), Positives = 77/184 (41%) Frame = +3 Query: 3 WNSDHGHVLEACKDSXXXXXXXXXXXXXIHFPVATKHTGVGTTDSALGDDGVLDIDTTIS 182 WN D EA ++S +H+PV ID + Sbjct: 78 WNDDQKRPREALQESLKKLQLDYLDLYLMHWPVPA-------------------IDHYVD 118 Query: 183 LETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIKPAVNQIETHPYFQRDSLVKF 362 W M L GLV+SIG+ N+ I + + + P +NQIE HP Q+ L Sbjct: 119 ---AWKGMIALQKEGLVKSIGVCNFQIHHLQRLIDETGVPPVINQIELHPLMQQRQLHAX 175 Query: 363 CQKHGICVTAHTPLGGSTANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTV 542 H I + +PL G D VI+ LA+KYGKTPAQ+V+RW L V Sbjct: 176 NATHKIQTESWSPLAQ--------GGEGVFDQKVIRELADKYGKTPAQIVIRWHLDCGLV 227 Query: 543 VIPK 554 VIPK Sbjct: 228 VIPK 231
>ARA1_YEAST (P38115) D-arabinose dehydrogenase [NAD(P)+] heavy chain (EC| 1.1.1.117) Length = 344 Score = 82.4 bits (202), Expect = 8e-16 Identities = 42/108 (38%), Positives = 64/108 (59%) Frame = +3 Query: 231 VRSIGISNYDIFLTRDCLAYAKIKPAVNQIETHPYFQRDSLVKFCQKHGICVTAHTPLGG 410 VR+IG+SN+ I + ++KP VNQ+ETHP+ + L KFC H I +TA++PLG Sbjct: 186 VRAIGVSNFSIEYLERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGS 245 Query: 411 STANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTVVIPK 554 A L P++K LAEKY T L++ + +++ T+VIP+ Sbjct: 246 HGAPN--------LKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPR 285
>CRO_RANTE (P02532) Rho crystallin| Length = 323 Score = 81.6 bits (200), Expect = 1e-15 Identities = 53/163 (32%), Positives = 83/163 (50%), Gaps = 7/163 (4%) Frame = +3 Query: 87 IHFPVATKHTGVGTTDSALGDDGVLDIDTTISLETTWHAMEDLVSMGLVRSIGISNY--- 257 +H+PV+ K +G S D I + L TW A+E GLVRS+G+SN+ Sbjct: 116 MHWPVSLKPSGA----SDPSDKDKPFIYDNVDLCATWEALEARKDAGLVRSLGVSNFNRR 171 Query: 258 --DIFLTRDCLAYAKIKPAVNQIETHPYFQRDSLVKFCQKHGICVTAHTPLGGSTANTEW 431 + L + L Y KP NQ+E H Y ++ L +C+ I + ++ LG S + W Sbjct: 172 QLERILNKPGLKY---KPVCNQVECHVYLNQNKLHSYCKSKDIVLVTYSVLG-SHRDRNW 227 Query: 432 --FGTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTVVIPK 554 LDDP++ +A KY +T A++ +R+ LQ+ VV+ K Sbjct: 228 VDLSLPVLLDDPILNKVAAKYNRTSAEIAMRFILQKGIVVLAK 270
>CRO_RANCA (P17264) Rho crystallin| Length = 323 Score = 81.6 bits (200), Expect = 1e-15 Identities = 53/163 (32%), Positives = 83/163 (50%), Gaps = 7/163 (4%) Frame = +3 Query: 87 IHFPVATKHTGVGTTDSALGDDGVLDIDTTISLETTWHAMEDLVSMGLVRSIGISNY--- 257 +H+PV+ K +G S D I + L TW A+E GLVRS+G+SN+ Sbjct: 116 MHWPVSLKPSGA----SDPSDKDKPFIYDNVDLCATWEALEARKDAGLVRSLGVSNFNRR 171 Query: 258 --DIFLTRDCLAYAKIKPAVNQIETHPYFQRDSLVKFCQKHGICVTAHTPLGGSTANTEW 431 + L + L Y KP NQ+E H Y ++ L +C+ I + ++ LG S + W Sbjct: 172 QLERILNKPGLKY---KPVCNQVECHVYLNQNKLHSYCKSKDIVLVTYSVLG-SHRDRNW 227 Query: 432 --FGTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTVVIPK 554 LDDP++ +A KY +T A++ +R+ LQ+ VV+ K Sbjct: 228 VDLSLPVLLDDPILNKIAAKYNRTSAEVAMRFILQKGIVVLAK 270
>DKGA_YERPE (Q8ZI40) 2,5-diketo-D-gluconic acid reductase A (EC 1.1.1.274)| (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (AKR5C) Length = 277 Score = 80.1 bits (196), Expect = 4e-15 Identities = 44/122 (36%), Positives = 62/122 (50%) Frame = +3 Query: 189 TTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIKPAVNQIETHPYFQRDSLVKFCQ 368 + W + L GL+RSIG+ N+ I + + I P VNQIE HP Q+ L + Sbjct: 118 SAWRELVTLKEQGLIRSIGVCNFHIPHLQRLIDETGIAPTVNQIELHPLLQQRQLHAWNA 177 Query: 369 KHGICVTAHTPLGGSTANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTVVI 548 H I + +PL G D +I+ LA++Y KTPAQ+V+RW L +VI Sbjct: 178 THHIATESWSPLAQ--------GGKGVFDQEIIRKLAQQYNKTPAQIVIRWHLDSGLIVI 229 Query: 549 PK 554 PK Sbjct: 230 PK 231
>DKGA_CORSC (P06632) 2,5-diketo-D-gluconic acid reductase A (EC 1.1.1.274)| (2,5-DKG reductase A) (2,5-DKGR A) (25DKGR-A) (AKR5C) Length = 277 Score = 78.6 bits (192), Expect = 1e-14 Identities = 47/120 (39%), Positives = 66/120 (55%) Frame = +3 Query: 195 WHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIKPAVNQIETHPYFQRDSLVKFCQKH 374 W M +L + GL RSIG+SN+ + +A + PAVNQIE HP +Q+ + + H Sbjct: 120 WEKMIELRAAGLTRSIGVSNHLVPHLERIVAATGVVPAVNQIELHPAYQQREITDWAAAH 179 Query: 375 GICVTAHTPLGGSTANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTVVIPK 554 + + + PLG + FG +PV + A +GKTPAQ VLRW LQ+ VV PK Sbjct: 180 DVKIESWGPLG--QGKYDLFGA-----EPV-TAAAAAHGKTPAQAVLRWHLQKGFVVFPK 231
>AK1CD_MESAU (P82809) Aldo-keto reductase family 1 member C13 (EC 1.1.1.-)| (Morphine 6-dehydrogenase) (EC 1.1.1.218) Length = 322 Score = 77.8 bits (190), Expect = 2e-14 Identities = 54/159 (33%), Positives = 81/159 (50%), Gaps = 7/159 (4%) Frame = +3 Query: 87 IHFPVATKHTGVGTTDSALGDDGVLDIDTTISLETTWHAMEDLVSMGLVRSIGISNYDI- 263 +H+PV K G D L + G L +DT + TW A+E GLV+SIG+SN+++ Sbjct: 116 MHYPVPMK---AGDNDFPLDEQGKLLLDT-VDFCATWEALEKXXDAGLVKSIGVSNFNMR 171 Query: 264 ----FLTRDCLAYAKIKPAVNQIETHPYFQRDSLVKFCQKHGICVTAHTPLGGSTANTEW 431 L + L Y KP NQ+E H Y + L+ +C+ I + A L G+ EW Sbjct: 172 QLERILNKPGLKY---KPVCNQVECHVYNNQSKLLDYCKSKDIVLVAFGAL-GTQRYKEW 227 Query: 432 FGTVS--CLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTV 542 S L+DPV+ A+ ++PA + LR+ +QR V Sbjct: 228 VDQDSPVLLNDPVLCGGAKXXXRSPALIALRYLVQRGVV 266
>AK1CD_MOUSE (Q8VC28) Aldo-keto reductase family 1 member C13 (EC 1.1.1.-)| Length = 323 Score = 76.6 bits (187), Expect = 4e-14 Identities = 52/159 (32%), Positives = 82/159 (51%), Gaps = 7/159 (4%) Frame = +3 Query: 87 IHFPVATKHTGVGTTDSALGDDGVLDIDTTISLETTWHAMEDLVSMGLVRSIGISNY--- 257 +H+PV K G D + + G +DT + TW +E+ GLV+SIG+SN+ Sbjct: 116 MHYPVPMKS---GDNDFPVNEQGKSLLDT-VDFCDTWERLEECKDAGLVKSIGVSNFNHR 171 Query: 258 --DIFLTRDCLAYAKIKPAVNQIETHPYFQRDSLVKFCQKHGICVTAHTPLGGSTANTEW 431 + L + L Y KP NQ+E H Y + L+ +C+ I + A+ L G+ EW Sbjct: 172 QLERILNKPGLKY---KPVCNQVECHLYLNQRKLLDYCESKDIVLVAYGAL-GTQRYKEW 227 Query: 432 FGTVS--CLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTV 542 S L+DPV+ +A+K ++PA + LR+ +QR V Sbjct: 228 VDQNSPVLLNDPVLCDVAKKNKRSPALIALRYLIQRGIV 266
>DKGB_YERPE (Q8ZH36) 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274)| (2,5-DKG reductase B) (2,5-DKGR B) (25DKGR-B) (AKR5D) Length = 267 Score = 75.5 bits (184), Expect = 1e-13 Identities = 44/111 (39%), Positives = 64/111 (57%), Gaps = 1/111 (0%) Frame = +3 Query: 222 MGLVRSIGISNYDIFLTRDCLAYAKIKP-AVNQIETHPYFQRDSLVKFCQKHGICVTAHT 398 +GL R IGISN+ I L + +A + A NQIE P Q ++V F +++GI VT++ Sbjct: 120 LGLTRQIGISNFTIDLMKQAIAAVGAEEIATNQIELSPLLQNRNVVDFAKQNGIAVTSYM 179 Query: 399 PLGGSTANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTVVIP 551 L A L +PVIK++AE++G TPAQ++L W +Q VIP Sbjct: 180 TLAYGKA----------LAEPVIKTIAEQHGATPAQVILSWAMQLGYGVIP 220
>YJ66_YEAST (P47137) Probable oxidoreductase YJR096W (EC 1.-.-.-)| Length = 282 Score = 74.7 bits (182), Expect = 2e-13 Identities = 41/123 (33%), Positives = 64/123 (52%), Gaps = 2/123 (1%) Frame = +3 Query: 192 TWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIK--PAVNQIETHPYFQRDSLVKFC 365 TW AM++ V GLV+SIG+SNY + L + ++K P VNQIE P+ R L +C Sbjct: 127 TWRAMQEAVDEGLVKSIGVSNYGKKHIDELLNWPELKHKPVVNQIEISPWIMRQELADYC 186 Query: 366 QKHGICVTAHTPLGGSTANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTVV 545 + G+ V A PL T +P + + ++ + P Q+++RW LQ + Sbjct: 187 KSKGLVVEAFAPLCHGYKMT----------NPDLLKVCKEVDRNPGQVLIRWSLQHGYLP 236 Query: 546 IPK 554 +PK Sbjct: 237 LPK 239
>DKGB_ECOLI (P30863) 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274)| (2,5-DKG reductase B) (2,5-DKGR B) (25DKGR-B) (AKR5D) Length = 267 Score = 70.1 bits (170), Expect = 4e-12 Identities = 44/126 (34%), Positives = 63/126 (50%), Gaps = 1/126 (0%) Frame = +3 Query: 177 ISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIKP-AVNQIETHPYFQRDSL 353 +S+E A+ + GL R IGISN+ I L +A + A NQIE PY Q + Sbjct: 105 VSVEEFMQALLEAKKQGLTREIGISNFTIPLMEKAIAAVGAENIATNQIELSPYLQNRKV 164 Query: 354 VKFCQKHGICVTAHTPLGGSTANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQR 533 V + ++HGI +T++ L A L D VI +A K+ TPAQ++L W + Sbjct: 165 VAWAKQHGIHITSYMTLAYGKA----------LKDEVIARIAAKHNATPAQVILAWAMGE 214 Query: 534 NTVVIP 551 VIP Sbjct: 215 GYSVIP 220
>DKGB_ECO57 (Q8X7Z7) 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274)| (2,5-DKG reductase B) (2,5-DKGR B) (25DKGR-B) (AKR5D) Length = 267 Score = 69.3 bits (168), Expect = 7e-12 Identities = 44/126 (34%), Positives = 63/126 (50%), Gaps = 1/126 (0%) Frame = +3 Query: 177 ISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIKP-AVNQIETHPYFQRDSL 353 +S+E A+ + GL R IGISN+ I L +A + A NQIE PY Q + Sbjct: 105 VSVEEFMQALLEAKKEGLTREIGISNFTIPLMEKAIAAVGAENIATNQIELSPYLQNRKV 164 Query: 354 VKFCQKHGICVTAHTPLGGSTANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQR 533 V + ++HGI +T++ L A L D VI +A K+ TPAQ++L W + Sbjct: 165 VAWAKQHGIHITSYMTLAYGKA----------LKDEVIARIAAKHNATPAQVILAWAMGE 214 Query: 534 NTVVIP 551 VIP Sbjct: 215 GYSVIP 220
>DKGB_SALTY (Q8ZRM7) 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274)| (2,5-DKG reductase B) (2,5-DKGR B) (25DKGR-B) (AKR5D) Length = 267 Score = 68.6 bits (166), Expect = 1e-11 Identities = 44/126 (34%), Positives = 61/126 (48%), Gaps = 1/126 (0%) Frame = +3 Query: 177 ISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIKP-AVNQIETHPYFQRDSL 353 +S+E A+ + GL R IGISN+ I L +A A NQIE PY Q + Sbjct: 105 VSVEEFMQALLEAKKQGLTREIGISNFTIPLMEKAIAAVGADNIATNQIELSPYLQNRKV 164 Query: 354 VKFCQKHGICVTAHTPLGGSTANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQR 533 V + + HGI +T++ L A L D VI +A K+ TPAQ++L W + Sbjct: 165 VDWAKAHGIHITSYMTLAYGKA----------LKDEVIARIAAKHNATPAQVILAWAMGE 214 Query: 534 NTVVIP 551 VIP Sbjct: 215 GYSVIP 220
>DKGB_SALTI (Q8Z988) 2,5-diketo-D-gluconic acid reductase B (EC 1.1.1.274)| (2,5-DKG reductase B) (2,5-DKGR B) (25DKGR-B) (AKR5D) Length = 267 Score = 66.6 bits (161), Expect = 4e-11 Identities = 43/126 (34%), Positives = 60/126 (47%), Gaps = 1/126 (0%) Frame = +3 Query: 177 ISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIKP-AVNQIETHPYFQRDSL 353 +S+E A+ + GL R IGISN+ I L +A A NQIE PY Q + Sbjct: 105 VSVEEFMQALLEAKKQGLTREIGISNFTIPLMEKAIAAVGADHIATNQIELSPYLQNRKV 164 Query: 354 VKFCQKHGICVTAHTPLGGSTANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQR 533 V + + HGI +T++ L A L D VI +A K+ TP Q++L W + Sbjct: 165 VDWAKAHGIHITSYMTLAYGKA----------LKDEVIARIAVKHNATPVQVILAWAMGE 214 Query: 534 NTVVIP 551 VIP Sbjct: 215 GYSVIP 220
>AFR_PIG (P82125) 1,5-anhydro-D-fructose reductase (EC 1.1.1.263) (AF| reductase) (Fragments) Length = 206 Score = 47.4 bits (111), Expect = 3e-05 Identities = 25/61 (40%), Positives = 36/61 (59%) Frame = +3 Query: 303 PAVNQIETHPYFQRDSLVKFCQKHGICVTAHTPLGGSTANTEWFGTVSCLDDPVIKSLAE 482 P NQIE+HPY + + F Q + VTA+ PLGGS+ V L+DPVI++ A+ Sbjct: 109 PVTNQIESHPYLTQK--ISFXQSRNVSVTAYRPLGGSSEG------VPLLEDPVIQTXAK 160 Query: 483 K 485 + Sbjct: 161 R 161
>YDBC_ECOLI (P25906) Putative oxidoreductase ydbC (EC 1.-.-.-)| Length = 286 Score = 43.1 bits (100), Expect = 5e-04 Identities = 34/126 (26%), Positives = 53/126 (42%), Gaps = 2/126 (1%) Frame = +3 Query: 180 SLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIKPAVNQIETHPYFQRDSLVK 359 S+E + + ++ GLV+ IG+SN + A+I N+ + D+++ Sbjct: 139 SIEASLTVLAEMQQQGLVKHIGLSNVTPTQVAEARKIAEIVCVQNEYNI-AHRADDAMID 197 Query: 360 FCQKHGICVTAHTPLGGSTANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQR-- 533 GI PLGG T L + +A G TP Q+ L W LQR Sbjct: 198 ALAHDGIAYVPFFPLGGFTP----------LQSSTLSDVAASLGATPMQVALAWLLQRSP 247 Query: 534 NTVVIP 551 N ++IP Sbjct: 248 NILLIP 253
>YEAE_ECOLI (P76234) Hypothetical protein yeaE| Length = 284 Score = 38.9 bits (89), Expect = 0.010 Identities = 38/142 (26%), Positives = 62/142 (43%), Gaps = 15/142 (10%) Frame = +3 Query: 174 TISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIK-----PAVNQIETHPYF 338 + + E T AME L++ G +R G+SN D YA ++ P NQ T+ Sbjct: 117 SFAFEETVAAMEKLIAQGKIRRWGVSNLD---------YADMQELWQLPGGNQCATNQVL 167 Query: 339 Q-------RDSLVKFCQKHGICVTAHTPL--GGSTANTEWFGTVSCLDDPVIKSLAEKYG 491 L+ +CQ+ + V A++PL G N L + V+ +A + Sbjct: 168 YHLGSRGIEYDLLPWCQQQQMPVMAYSPLAQAGRLRN-------GLLKNAVVNEIAHAHN 220 Query: 492 KTPAQLVLRWGLQRNTVV-IPK 554 + AQ++L W + V+ IPK Sbjct: 221 ISAAQVLLAWVISHQGVMAIPK 242
>YCSN_BACSU (P42972) Hypothetical oxidoreductase ycsN (EC 1.-.-.-)| Length = 300 Score = 35.8 bits (81), Expect = 0.084 Identities = 36/145 (24%), Positives = 51/145 (35%), Gaps = 3/145 (2%) Frame = +3 Query: 3 WNSDHGHVLEACKDSXXXXXXXXXXXXXIHFPVATKHTGVGTTDSALGDDGVLDIDTTIS 182 +N+ H+L + + S IH P D + +GV + Sbjct: 99 YNTSKSHILASVEQSLMNLRTDYIDMLLIHRP-----------DPLMDPEGVAE------ 141 Query: 183 LETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIKPAVNQIETHPY---FQRDSL 353 A + L G VR G+SN+ R +Y K NQIE Y D Sbjct: 142 ------AFQALKCSGKVRYFGVSNFKDHQYRMLESYLPEKLVTNQIELSAYELENMLDGT 195 Query: 354 VKFCQKHGICVTAHTPLGGSTANTE 428 + CQ+ I A +PL G TE Sbjct: 196 LNLCQEKRIPPMAWSPLAGGKVFTE 220
>MORA_RABIT (P82810) Morphine 6-dehydrogenase (EC 1.1.1.218) (Fragments)| Length = 125 Score = 34.3 bits (77), Expect = 0.24 Identities = 30/107 (28%), Positives = 44/107 (41%) Frame = +3 Query: 234 RSIGISNYDIFLTRDCLAYAKIKPAVNQIETHPYFQRDSLVKFCQKHGICVTAHTPLGGS 413 +SIG+SN++ K NQ+E HPY Q I + A++ LG S Sbjct: 40 KSIGVSNFNH------------KRVXNQVEXHPYLN--------QSKDIVLVAYSALGSS 79 Query: 414 TANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQRNTVVIPK 554 DP + ++PA + LR+ LQR VV+ K Sbjct: 80 R-------------DP--------WKQSPALIALRYQLQRGVVVLAK 105
>GS69_BACSU (P80874) General stress protein 69 (EC 1.1.1.-) (GSP69) (AKR11B)| Length = 331 Score = 33.1 bits (74), Expect = 0.54 Identities = 36/148 (24%), Positives = 58/148 (39%), Gaps = 26/148 (17%) Frame = +3 Query: 168 DTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYA---KIKPAVNQIETH--- 329 D + +E T M++L G +R+IG+SN+ I A A I+P N E Sbjct: 128 DPLVPIEETAEVMKELYDAGKIRAIGVSNFSIEQMDTFRAVAPLHTIQPPYNLFEREMEE 187 Query: 330 ---PYFQRDSLV--------------KFCQKH---GICVTAHTPLGGSTANTEWFGTVSC 449 PY + + + K +++ G + H P E+ V+ Sbjct: 188 SVLPYAKDNKITTLLYGSLCRGLLTGKMTEEYTFEGDDLRNHDPKFQKPRFKEYLSAVNQ 247 Query: 450 LDDPVIKSLAEKYGKTPAQLVLRWGLQR 533 LD K +YGK+ L +RW L + Sbjct: 248 LD----KLAKTRYGKSVIHLAVRWILDQ 271
>Y2320_MYCBO (P63485) Hypothetical protein Mb2320| Length = 323 Score = 33.1 bits (74), Expect = 0.54 Identities = 35/128 (27%), Positives = 52/128 (40%), Gaps = 22/128 (17%) Frame = +3 Query: 204 MEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIKPAVNQIE---THPYFQRDSLVKFCQKH 374 M DL+ G + + G+SNY + R A NQ+ HP D LV F + Sbjct: 132 MRDLLDSGDIGAAGVSNYSLARWRKADAALGRPVVSNQVHFSLAHPDALED-LVPFAELE 190 Query: 375 GICVTAHTPL---------------GGSTANTEWFGTVSCLD-DPV---IKSLAEKYGKT 497 V A++PL GG A FGT + +P+ ++++A Sbjct: 191 NRIVIAYSPLAQGLLGGKYGLENRPGGVRALNPLFGTENLRRIEPLLATLRAIAVDVDAK 250 Query: 498 PAQLVLRW 521 PAQ+ L W Sbjct: 251 PAQVALAW 258
>Y2298_MYCTU (P63484) Hypothetical protein Rv2298/MT2355| Length = 323 Score = 33.1 bits (74), Expect = 0.54 Identities = 35/128 (27%), Positives = 52/128 (40%), Gaps = 22/128 (17%) Frame = +3 Query: 204 MEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIKPAVNQIE---THPYFQRDSLVKFCQKH 374 M DL+ G + + G+SNY + R A NQ+ HP D LV F + Sbjct: 132 MRDLLDSGDIGAAGVSNYSLARWRKADAALGRPVVSNQVHFSLAHPDALED-LVPFAELE 190 Query: 375 GICVTAHTPL---------------GGSTANTEWFGTVSCLD-DPV---IKSLAEKYGKT 497 V A++PL GG A FGT + +P+ ++++A Sbjct: 191 NRIVIAYSPLAQGLLGGKYGLENRPGGVRALNPLFGTENLRRIEPLLATLRAIAVDVDAK 250 Query: 498 PAQLVLRW 521 PAQ+ L W Sbjct: 251 PAQVALAW 258
>A115_TOBAC (P40691) Auxin-induced protein PCNT115| Length = 307 Score = 32.7 bits (73), Expect = 0.71 Identities = 20/81 (24%), Positives = 37/81 (45%) Frame = +3 Query: 165 IDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIKPAVNQIETHPYFQR 344 +DT + +E T ++ LV G ++ IG+S R A I + Sbjct: 138 VDTRVPIEITVGELKKLVEEGKLKYIGLSEASASTIRRAHAVHPITAVQLEWSLWSRDVE 197 Query: 345 DSLVKFCQKHGICVTAHTPLG 407 + ++ C++ GI + A++PLG Sbjct: 198 EEIIPTCRELGIGIVAYSPLG 218
>GSH0_RAT (P48508) Glutamate--cysteine ligase regulatory subunit (EC 6.3.2.2)| (Gamma-glutamylcysteine synthetase) (Gamma-ECS) (GCS light chain) (Glutamate--cysteine ligase modifier subunit) Length = 274 Score = 32.0 bits (71), Expect = 1.2 Identities = 20/71 (28%), Positives = 33/71 (46%), Gaps = 3/71 (4%) Frame = +3 Query: 117 GVGTTDSALGDDGVLDIDTTISLETT---WHAMEDLVSMGLVRSIGISNYDIFLTRDCLA 287 GV DS + ++ +SLE W +E+LV + +IG S+ D Sbjct: 118 GVAQLDSVIMASPPIEDGVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQ 177 Query: 288 YAKIKPAVNQI 320 +A++KP NQ+ Sbjct: 178 WAQVKPNSNQV 188
>GSH0_MOUSE (O09172) Glutamate--cysteine ligase regulatory subunit (EC 6.3.2.2)| (Gamma-glutamylcysteine synthetase) (Gamma-ECS) (GCS light chain) (Glutamate--cysteine ligase modifier subunit) Length = 274 Score = 32.0 bits (71), Expect = 1.2 Identities = 20/71 (28%), Positives = 33/71 (46%), Gaps = 3/71 (4%) Frame = +3 Query: 117 GVGTTDSALGDDGVLDIDTTISLETT---WHAMEDLVSMGLVRSIGISNYDIFLTRDCLA 287 GV DS + ++ +SLE W +E+LV + +IG S+ D Sbjct: 118 GVAQLDSVIMASPPIEDGVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQ 177 Query: 288 YAKIKPAVNQI 320 +A++KP NQ+ Sbjct: 178 WAQVKPNSNQV 188
>GSH0_HUMAN (P48507) Glutamate--cysteine ligase regulatory subunit (EC 6.3.2.2)| (Gamma-glutamylcysteine synthetase) (Gamma-ECS) (GCS light chain) (Glutamate--cysteine ligase modifier subunit) Length = 274 Score = 31.6 bits (70), Expect = 1.6 Identities = 20/71 (28%), Positives = 33/71 (46%), Gaps = 3/71 (4%) Frame = +3 Query: 117 GVGTTDSALGDDGVLDIDTTISLETT---WHAMEDLVSMGLVRSIGISNYDIFLTRDCLA 287 GV DS + ++ +SLE W +E+LV + +IG S+ D Sbjct: 118 GVAQLDSVIIASPPIEDGVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQ 177 Query: 288 YAKIKPAVNQI 320 +A++KP NQ+ Sbjct: 178 WAQVKPNSNQV 188
>PLR1_SCHPO (O14295) Pyridoxal reductase (EC 1.1.1.65) (PL reductase) (PL-red)| Length = 333 Score = 31.2 bits (69), Expect = 2.1 Identities = 20/83 (24%), Positives = 40/83 (48%), Gaps = 4/83 (4%) Frame = +3 Query: 165 IDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIKPAVNQIETHPYFQR 344 +D + +ETT ++ V G + +G+S + A+A + A ++E + F R Sbjct: 125 VDPNVPIETTMKTLKGFVDSGKISCVGLSEVSAETIK--RAHAVVPIAAVEVE-YSLFSR 181 Query: 345 D----SLVKFCQKHGICVTAHTP 401 D ++ C+K I + A++P Sbjct: 182 DIETNGIMDICRKLSIPIIAYSP 204
>STCV_EMENI (Q00727) Putative sterigmatocystin biosynthesis dehydrogenase stcV| (EC 1.1.1.-) Length = 387 Score = 30.8 bits (68), Expect = 2.7 Identities = 34/147 (23%), Positives = 61/147 (41%), Gaps = 19/147 (12%) Frame = +3 Query: 168 DTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYAKIKPAVNQIE-------T 326 D + S+E ++ LV+ G V +IGIS+ ++ C YA+ + Sbjct: 151 DFSTSVEEVMQSLHHLVAAGKVLNIGISDAPAWVVAKCNEYARFHGLTRFCVYQGRWACS 210 Query: 327 HPYFQRDSLVKFCQKHGICVTAHTPLG-GSTANTEWF---GTVSC--------LDDPVIK 470 + F+R+ ++ CQ G+ + LG G + E F GT + L + Sbjct: 211 YRDFERE-ILPMCQSEGLALAPWGALGRGQYKSAEEFQQEGTRNMGPQEEKHRLMGAKLT 269 Query: 471 SLAEKYGKTPAQLVLRWGLQRNTVVIP 551 + E+ G A + L + L ++ V P Sbjct: 270 EVGERKGVAAAAIALAYLLHKSPYVFP 296
>BISC_RHOSH (P54934) Biotin sulfoxide reductase (EC 1.-.-.-) (BDS reductase)| (BSO reductase) Length = 744 Score = 30.8 bits (68), Expect = 2.7 Identities = 14/42 (33%), Positives = 22/42 (52%) Frame = +3 Query: 408 GSTANTEWFGTVSCLDDPVIKSLAEKYGKTPAQLVLRWGLQR 533 G + EW T++ L I++LA +T + L + W LQR Sbjct: 261 GRPKDAEWASTITGLPAEAIRALAGDLPRTRSMLTVSWSLQR 302
>NHR11_CAEEL (Q23294) Nuclear hormone receptor family member nhr-11| Length = 459 Score = 29.6 bits (65), Expect = 6.0 Identities = 25/86 (29%), Positives = 37/86 (43%) Frame = -2 Query: 444 RPCRTTRCWQWSRPGGYER*RRFRASGRTSQESRAGSKGASRFGSPRALSWRTPSSPW*G 265 R CR +C+ R +R + ++SR S A SP S R SSP Sbjct: 62 RECRLRKCYSAGMRSELVRSKRENFACTRRKDSRNNSDAAPNSNSP---STRQSSSP--E 116 Query: 264 RCRSC*FRCYEQVPWKQDLPLHATLS 187 F+ +E+ P +DLPL ++S Sbjct: 117 EMDDWSFQMFEEKPKIEDLPLTPSIS 142
>EF1A_METKA (Q8TYP6) Elongation factor 1-alpha (EF-1-alpha) (Elongation factor| Tu) (EF-Tu) Length = 423 Score = 29.3 bits (64), Expect = 7.9 Identities = 17/50 (34%), Positives = 25/50 (50%) Frame = +3 Query: 114 TGVGTTDSALGDDGVLDIDTTISLETTWHAMEDLVSMGLVRSIGISNYDI 263 TGVGT + GVL++ T+ E + A G VRSI + + +I Sbjct: 226 TGVGTVPVGRVETGVLEVGDTVRFEPAYTATGGRKGEGEVRSIEMHHEEI 275 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 71,917,153 Number of Sequences: 219361 Number of extensions: 1446940 Number of successful extensions: 5228 Number of sequences better than 10.0: 99 Number of HSP's better than 10.0 without gapping: 4894 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5097 length of database: 80,573,946 effective HSP length: 105 effective length of database: 57,541,041 effective search space used: 4545742239 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
