>EXOSX_MOUSE (P56960) Exosome component 10 (Polymyositis/scleroderma autoantigen|
           2 homolog) (Autoantigen PM/Scl 2 homolog)
          Length = 887

 Score = 45.8 bits (107), Expect = 9e-05
 Identities = 37/142 (26%), Positives = 61/142 (42%)
 Frame = +3

Query: 168 GALCIMQIAFPDAVYLVDAIEGGKELVEACKPALESDHVTKVIHDCKRDSEALYFQFGIK 347
           G  C+MQI+     ++VD +E   ++      +L    + KV H    D E L   FG+ 
Sbjct: 324 GLTCLMQISTRTEDFIVDTLELRSDMY-ILNESLTDPAIVKVFHGADSDIEWLQKDFGLY 382

Query: 348 LHNVMDTQIAYSLIEEQEGKKRAYDVYISFVSLLADPRYCGMPYPEKEEVRTLLRQDPNF 527
           + N+ DT  A  L+      + + D  +          YCG+   ++ ++          
Sbjct: 383 VVNMFDTHQAARLLNLA---RHSLDHLLRL--------YCGVESNKQYQLAD-------- 423

Query: 528 WKNRPLSEMMIRAATDDVRFLL 593
           W+ RPL E M+  A DD  +LL
Sbjct: 424 WRIRPLPEEMLSYARDDTHYLL 445

>YD81_SCHPO (Q10146) Hypothetical protein C1F3.01 in chromosome I|
          Length = 777

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 37/142 (26%), Positives = 64/142 (45%)
 Frame = +3

Query: 168 GALCIMQIAFPDAVYLVDAIEGGKELVEACKPALESDHVTKVIHDCKRDSEALYFQFGIK 347
           G +C+MQI+  +  ++VD +E  +EL EA      + ++ KV H    D   L   FG+ 
Sbjct: 254 GFVCLMQISNREKDWIVDTLELREEL-EALNVVFTNPNIIKVFHGATMDIIWLQRDFGLY 312

Query: 348 LHNVMDTQIAYSLIEEQEGKKRAYDVYISFVSLLADPRYCGMPYPEKEEVRTLLRQDPNF 527
           + N+ DT  A  ++   EG   A+ +           +YC     ++ ++          
Sbjct: 313 VVNLFDTYYATKVL-GFEGHGLAFLL----------QKYCDYDADKRYQMAD-------- 353

Query: 528 WKNRPLSEMMIRAATDDVRFLL 593
           W+ RPL   M++ A  D  +LL
Sbjct: 354 WRIRPLPREMLKYAQSDTHYLL 375

>EXOSX_HUMAN (Q01780) Exosome component 10 (Polymyositis/scleroderma autoantigen|
           2) (Autoantigen PM/Scl 2) (Polymyositis/scleroderma
           autoantigen 100 kDa) (PM/Scl-100) (P100
           polymyositis-scleroderma overlap syndrome-associated
           autoantigen)
          Length = 885

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 35/142 (24%), Positives = 60/142 (42%)
 Frame = +3

Query: 168 GALCIMQIAFPDAVYLVDAIEGGKELVEACKPALESDHVTKVIHDCKRDSEALYFQFGIK 347
           G  C+MQI+     +++D +E   ++      +L    + KV H    D E L   FG+ 
Sbjct: 324 GLTCLMQISTRTEDFIIDTLELRSDMY-ILNESLTDPAIVKVFHGADSDIEWLQKDFGLY 382

Query: 348 LHNVMDTQIAYSLIEEQEGKKRAYDVYISFVSLLADPRYCGMPYPEKEEVRTLLRQDPNF 527
           + N+ DT  A  L+      + + D  +          YC +   ++ ++          
Sbjct: 383 VVNMFDTHQAARLLNLG---RHSLDHLLKL--------YCNVDSNKQYQLAD-------- 423

Query: 528 WKNRPLSEMMIRAATDDVRFLL 593
           W+ RPL E M+  A DD  +LL
Sbjct: 424 WRIRPLPEEMLSYARDDTHYLL 445

>RRP6_YEAST (Q12149) Exosome complex exonuclease RRP6 (EC 3.1.13.-) (Ribosomal|
           RNA-processing protein 6)
          Length = 733

 Score = 35.4 bits (80), Expect = 0.13
 Identities = 37/145 (25%), Positives = 56/145 (38%), Gaps = 2/145 (1%)
 Frame = +3

Query: 168 GALCIMQIAFPDAVYLVDAIEGGKELVEACKPALESDHVTKVIHDCKRDSEALYFQFGIK 347
           G +C+MQI+  +  YLVD ++  +E +        +  + KV H    D   L    G+ 
Sbjct: 249 GIVCLMQISTRERDYLVDTLK-LRENLHILNEVFTNPSIVKVFHGAFMDIIWLQRDLGLY 307

Query: 348 LHNVMDTQIAYSLIEEQEGKKRAYDVYI--SFVSLLADPRYCGMPYPEKEEVRTLLRQDP 521
           +  + DT  A   I    G  R    Y+  +F +     +Y                   
Sbjct: 308 VVGLFDTYHASKAI----GLPRHSLAYLLENFANFKTSKKY-----------------QL 346

Query: 522 NFWKNRPLSEMMIRAATDDVRFLLN 596
             W+ RPLS+ M   A  D  FLLN
Sbjct: 347 ADWRIRPLSKPMTAYARADTHFLLN 371

>GAK_HUMAN (O14976) Cyclin G-associated kinase (EC 2.7.11.1)|
          Length = 1311

 Score = 33.1 bits (74), Expect = 0.62
 Identities = 19/50 (38%), Positives = 25/50 (50%), Gaps = 2/50 (4%)
 Frame = -1

Query: 274  DSSAGLQASTSSFPPS--IASTK*TASGNAICMIQRAPLRQRSTPSQSNP 131
            D S+GLQ S + FPP   I  T  T  G++     R P +  S P Q+ P
Sbjct: 1088 DLSSGLQGSPAGFPPGGFIPKTATTPKGSSSWQTSRPPAQGASWPPQAKP 1137

>RND_ECOLI (P09155) Ribonuclease D (EC 3.1.26.3) (RNase D)|
          Length = 375

 Score = 31.2 bits (69), Expect = 2.4
 Identities = 32/112 (28%), Positives = 47/112 (41%)
 Frame = +3

Query: 258 KPALESDHVTKVIHDCKRDSEALYFQFGIKLHNVMDTQIAYSLIEEQEGKKRAYDVYISF 437
           K  L    +TK +H    D E     FG     ++DTQI  +      G+  ++     F
Sbjct: 67  KAILRDPSITKFLHAGSEDLEVFLNVFGELPQPLIDTQILAAFC----GRPMSW----GF 118

Query: 438 VSLLADPRYCGMPYPEKEEVRTLLRQDPNFWKNRPLSEMMIRAATDDVRFLL 593
            S++ +  Y G+   +K E RT        W  RPL+E     A  DV +LL
Sbjct: 119 ASMVEE--YSGVTL-DKSESRT-------DWLARPLTERQCEYAAADVWYLL 160

>FABG_BACSU (P51831) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)|
           (3-ketoacyl-acyl carrier protein reductase)
          Length = 246

 Score = 30.4 bits (67), Expect = 4.0
 Identities = 13/33 (39%), Positives = 21/33 (63%)
 Frame = -1

Query: 184 MIQRAPLRQRSTPSQSNPITNFLAAEGSRNSTG 86
           M+++ PL +   PS  + +  FLA+EG+R  TG
Sbjct: 203 MLKQIPLARFGEPSDVSSVVTFLASEGARYMTG 235

>TRPA1_HUMAN (O75762) Transient receptor potential cation channel subfamily A|
            member 1 (Ankyrin-like with transmembrane domains protein
            1) (Transformation sensitive-protein p120)
          Length = 1119

 Score = 30.0 bits (66), Expect = 5.3
 Identities = 18/38 (47%), Positives = 24/38 (63%)
 Frame = +1

Query: 58   FMLLLNLVNYRSSFLSPLLPRNW*LDLTAKVLTFAAMV 171
            F ++L  +NYR SFL P L RN   +L   VL+FA +V
Sbjct: 909  FSMMLGDINYRESFLEPYL-RN---ELAHPVLSFAQLV 942

>CDR_PYRFU (Q8U1M0) Coenzyme A disulfide reductase (EC 1.8.1.14)|
           (CoA-disulfide reductase) (CoADR)
          Length = 442

 Score = 29.6 bits (65), Expect = 6.9
 Identities = 16/53 (30%), Positives = 23/53 (43%)
 Frame = +3

Query: 339 GIKLHNVMDTQIAYSLIEEQEGKKRAYDVYISFVSLLADPRYCGMPYPEKEEV 497
           G  +   MD +I  + + E E  K  YDV  +F+     P Y    YP   E+
Sbjct: 324 GTSITKFMDLEIGKTGLTENEAVKEGYDVRTAFIKANTKPHY----YPGGREI 372

>FABI_BACSU (P54616) Enoyl-[acyl-carrier-protein] reductase [NADH] (EC 1.3.1.9)|
           (NADH-dependent enoyl-ACP reductase) (Cold shock-induced
           protein 15) (CSI15) (Vegetative protein 241) (VEG241)
          Length = 258

 Score = 29.6 bits (65), Expect = 6.9
 Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 2/57 (3%)
 Frame = -1

Query: 250 STSSFPPSIASTK*TASGNAIC--MIQRAPLRQRSTPSQSNPITNFLAAEGSRNSTG 86
           S S+ P    S K  +  N+I   + +RAPLR+ +TP +      FL ++ SR  TG
Sbjct: 188 SISAGPIRTLSAKGISDFNSILKDIEERAPLRRTTTPEEVGDTAAFLFSDMSRGITG 244

>CAC1G_RAT (O54898) Voltage-dependent T-type calcium channel alpha-1G subunit|
            (Voltage-gated calcium channel alpha subunit Cav3.1)
          Length = 2254

 Score = 29.3 bits (64), Expect = 9.0
 Identities = 18/61 (29%), Positives = 29/61 (47%), Gaps = 6/61 (9%)
 Frame = -1

Query: 235  PPSIASTK*TASGN------AICMIQRAPLRQRSTPSQSNPITNFLAAEGSRNSTGS*PG 74
            PPSI+     + G+       +C+ +RAP      PS S+P+ +  A+   +  T S  G
Sbjct: 2185 PPSISIDPPESQGSRPPCSPGVCLRRRAPASDSKDPSVSSPLDSTAASPSPKKDTLSLSG 2244

Query: 73   L 71
            L
Sbjct: 2245 L 2245

>ARLY_NOCFA (Q5YYD2) Argininosuccinate lyase (EC 4.3.2.1) (Arginosuccinase)|
           (ASAL)
          Length = 473

 Score = 29.3 bits (64), Expect = 9.0
 Identities = 18/61 (29%), Positives = 27/61 (44%)
 Frame = +3

Query: 144 EGVDLCRNGALCIMQIAFPDAVYLVDAIEGGKELVEACKPALESDHVTKVIHDCKRDSEA 323
           +GV     G L ++      A    DA+  GK  ++A +P L + H+    H   RD E 
Sbjct: 132 DGVRRVAAGVLDVVDALVEQAAAHPDAVMPGKTHLQAAQPVLLAHHLLAHAHPLLRDIER 191

Query: 324 L 326
           L
Sbjct: 192 L 192

>DPOG2_MOUSE (Q9QZM2) DNA polymerase gamma subunit 2, mitochondrial precursor|
           (EC 2.7.7.7) (Mitochondrial DNA polymerase accessory
           subunit) (PolG-beta) (MtPolB) (DNA polymerase gamma
           accessory 55 kDa subunit) (p55)
          Length = 459

 Score = 29.3 bits (64), Expect = 9.0
 Identities = 13/26 (50%), Positives = 19/26 (73%)
 Frame = -1

Query: 79  PGLVTT*KGRDGNSTLLPCGVLAIGG 2
           PG V+T +GRDG   ++PC VL++ G
Sbjct: 290 PGNVSTIQGRDGRKNVVPC-VLSVSG 314

>CDR_PYRHO (O58308) Coenzyme A disulfide reductase (EC 1.8.1.14)|
           (CoA-disulfide reductase) (CoADR)
          Length = 445

 Score = 29.3 bits (64), Expect = 9.0
 Identities = 16/53 (30%), Positives = 23/53 (43%)
 Frame = +3

Query: 339 GIKLHNVMDTQIAYSLIEEQEGKKRAYDVYISFVSLLADPRYCGMPYPEKEEV 497
           G  +   MD +I  + + E E  K  YDV  +F+     P Y    YP   E+
Sbjct: 327 GTAVTKFMDVEIGKTGLTEMEALKEGYDVRTAFIKASTRPHY----YPGGREI 375


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 92,388,499
Number of Sequences: 219361
Number of extensions: 1978953
Number of successful extensions: 5232
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 5083
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5224
length of database: 80,573,946
effective HSP length: 107
effective length of database: 57,102,319
effective search space used: 5196311029
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)