ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bags34i20 |
|---|---|
| Clone Library Name | barley_pub |
>GBLP_ORYSA (P49027) Guanine nucleotide-binding protein beta subunit-like| protein (GPB-LR) (RWD) Length = 334 Score = 333 bits (854), Expect = 2e-91 Identities = 154/171 (90%), Positives = 162/171 (94%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G GWVSCVRFSPN F PTIVSGSWDR+VKVWNLTNCKLRC L+GHGGYV+AVAVSPDGS Sbjct: 163 GHNGWVSCVRFSPNTFQPTIVSGSWDRTVKVWNLTNCKLRCNLEGHGGYVNAVAVSPDGS 222 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKH 370 LCASGGKDGVTLLWDL EGKRLYSLDAGSII+SLCFSPNRYWLCAATQDSIKIWDLESKH Sbjct: 223 LCASGGKDGVTLLWDLAEGKRLYSLDAGSIIHSLCFSPNRYWLCAATQDSIKIWDLESKH 282 Query: 371 IVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISGFSYS 523 IVQDL+PE+PVS QMLYCT L+WSADGSTLYAGYTDGTIRIYKISGFSY+ Sbjct: 283 IVQDLKPEIPVSKNQMLYCTSLNWSADGSTLYAGYTDGTIRIYKISGFSYA 333 Score = 55.8 bits (133), Expect = 8e-08 Identities = 48/177 (27%), Positives = 85/177 (48%), Gaps = 22/177 (12%) Frame = +2 Query: 44 SPNNFAPTIVSGSWDRSVKVWNLTNCKLRC--------------TLDGHGGYVSAVAVSP 181 +P + +P IVS S D+S+ VW+LTN L GH +V V +S Sbjct: 26 TPIDNSPFIVSSSRDKSLLVWDLTNPVQNVGEGAGASEYGVPFRRLTGHSHFVQDVVLSS 85 Query: 182 DGSLCASGGKDGVTLLWDLTEG---KRLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKI 349 DG SG DG LWDL+ G +R D + S+ FS + + +A++D +IK+ Sbjct: 86 DGQFALSGSWDGELRLWDLSTGVTTRRFVGHDKD--VLSVAFSVDNRQIVSASRDRTIKL 143 Query: 350 WDL--ESKHIVQDLRPEVPVSSKQMLYCTCLSWSAD--GSTLYAGYTDGTIRIYKIS 508 W+ E K+ + ++ + +C+ +S + T+ +G D T++++ ++ Sbjct: 144 WNTLGECKYTIGG---DLGGGEGHNGWVSCVRFSPNTFQPTIVSGSWDRTVKVWNLT 197 Score = 45.8 bits (107), Expect = 8e-05 Identities = 39/156 (25%), Positives = 68/156 (43%), Gaps = 10/156 (6%) Frame = +2 Query: 71 VSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWD-LTEG 247 +SGSWD +++W+L+ GH V +VA S D S +D LW+ L E Sbjct: 91 LSGSWDGELRLWDLSTGVTTRRFVGHDKDVLSVAFSVDNRQIVSASRDRTIKLWNTLGEC 150 Query: 248 KRLYSLDAG------SIINSLCFSPNRYW---LCAATQDSIKIWDLESKHIVQDLRPEVP 400 K D G ++ + FSPN + + + ++K+W+L + + +L Sbjct: 151 KYTIGGDLGGGEGHNGWVSCVRFSPNTFQPTIVSGSWDRTVKVWNLTNCKLRCNLEGHGG 210 Query: 401 VSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 Y ++ S DGS +G DG ++ ++ Sbjct: 211 -------YVNAVAVSPDGSLCASGGKDGVTLLWDLA 239
>GBLP_NICPL (P93340) Guanine nucleotide-binding protein beta subunit-like| protein Length = 326 Score = 262 bits (669), Expect = 6e-70 Identities = 123/175 (70%), Positives = 142/175 (81%), Gaps = 11/175 (6%) Frame = +2 Query: 23 WVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCAS 202 WVSCVRFSPNN PTIVSGSWDR+VK+WNLTNCKLR TL GH GYV+ AVSPDGSLCAS Sbjct: 152 WVSCVRFSPNNLQPTIVSGSWDRTVKIWNLTNCKLRATLAGHTGYVNTTAVSPDGSLCAS 211 Query: 203 GGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQD 382 GGKDGV LLWDL EGK+LYSL++GSII+SLCFSPNRYWLCAAT+ SIKIWDLESK IV D Sbjct: 212 GGKDGVILLWDLAEGKKLYSLESGSIIHSLCFSPNRYWLCAATESSIKIWDLESKTIVDD 271 Query: 383 LRPEVPVSSK-----------QMLYCTCLSWSADGSTLYAGYTDGTIRIYKISGF 514 L+ ++ S+ +++YCT L WSADGSTL++GYTDG IR++ I F Sbjct: 272 LKVDLKQESEMSAEGTASGKNKVIYCTSLGWSADGSTLFSGYTDGLIRVWGIGRF 326 Score = 69.3 bits (168), Expect = 7e-12 Identities = 52/178 (29%), Positives = 87/178 (48%), Gaps = 11/178 (6%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKL-----RCTLDGHGGYVSAVA 172 R T WV+ + +P + + IV+ S D+S+ VW+LT R L GHG +V V Sbjct: 13 RAHTDWVTAIA-TPVDNSDMIVTSSRDKSIIVWSLTKDGPQYGVPRRRLTGHGHFVQDVV 71 Query: 173 VSPDGSLCASGGKDGVTLLWDLTEG--KRLYSLDAGSIINSLCFSPNRYWLCAATQDSIK 346 +S DG SG DG LWDL G R + +++ + NR + A+ SI+ Sbjct: 72 LSSDGMFALSGSWDGELRLWDLQAGTTARRFVGHTKDVLSVAFSADNRQIVSASRDKSIR 131 Query: 347 IWDL--ESKHIVQDLRPEVPVSSKQMLYCTCLSWSADG--STLYAGYTDGTIRIYKIS 508 +W+ E K+I+QD + +C+ +S + T+ +G D T++I+ ++ Sbjct: 132 LWNTLGECKYIIQD-------GDSHSDWVSCVRFSPNNLQPTIVSGSWDRTVKIWNLT 182
>GBLP_TOBAC (P49026) Guanine nucleotide-binding protein beta subunit-like| protein Length = 326 Score = 261 bits (668), Expect = 7e-70 Identities = 123/175 (70%), Positives = 143/175 (81%), Gaps = 11/175 (6%) Frame = +2 Query: 23 WVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCAS 202 WVSCVRFSPNN PTIVSGSWDR+VK+WNLTNCKLR TL GH GYV+ AVSPDGSLCAS Sbjct: 152 WVSCVRFSPNNLQPTIVSGSWDRTVKIWNLTNCKLRLTLAGHTGYVNTPAVSPDGSLCAS 211 Query: 203 GGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQD 382 GGKDGV LLWDL EGK+LYSL++GSII+SLCFSPNRYWLCAAT+ SIKIWDLESK IV D Sbjct: 212 GGKDGVILLWDLAEGKKLYSLESGSIIHSLCFSPNRYWLCAATESSIKIWDLESKSIVDD 271 Query: 383 LRPEVPVSSK-----------QMLYCTCLSWSADGSTLYAGYTDGTIRIYKISGF 514 L+ ++ S+ +++YCT LSWSADGSTL++GYTDG IR++ I + Sbjct: 272 LKVDLKQESEMSSEGTASGKNKVIYCTSLSWSADGSTLFSGYTDGLIRVWGIDRY 326 Score = 65.9 bits (159), Expect = 8e-11 Identities = 50/178 (28%), Positives = 85/178 (47%), Gaps = 11/178 (6%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKL-----RCTLDGHGGYVSAVA 172 R T WV+ + + +N + IV+ S D+S+ VW++T R L GHG +V V Sbjct: 13 RAHTDWVTAIATAVDN-SDMIVTSSRDKSIIVWSITKDGPQYGVPRRRLTGHGHFVQDVV 71 Query: 173 VSPDGSLCASGGKDGVTLLWDLTEG--KRLYSLDAGSIINSLCFSPNRYWLCAATQDSIK 346 +S DG SG DG LWDL G R + +++ NR + A+ SI+ Sbjct: 72 LSSDGMFALSGSWDGELRLWDLQAGTTARRFVGHTKDVLSVAFSVDNRQIVSASRDKSIR 131 Query: 347 IWDL--ESKHIVQDLRPEVPVSSKQMLYCTCLSWSADG--STLYAGYTDGTIRIYKIS 508 +W+ E K+ +QD + +C+ +S + T+ +G D T++I+ ++ Sbjct: 132 LWNTLGECKYTIQD-------GDSHSDWVSCVRFSPNNLQPTIVSGSWDRTVKIWNLT 182
>GBLP_MEDSA (O24076) Guanine nucleotide-binding protein beta subunit-like| protein Length = 325 Score = 259 bits (663), Expect = 3e-69 Identities = 122/175 (69%), Positives = 143/175 (81%), Gaps = 11/175 (6%) Frame = +2 Query: 23 WVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCAS 202 WVSCVRFSP+ PTIVS SWDR+VKVWNLTNCKLR TL GH GYV+ VAVSPDGSLCAS Sbjct: 151 WVSCVRFSPSTPQPTIVSASWDRTVKVWNLTNCKLRNTLAGHSGYVNTVAVSPDGSLCAS 210 Query: 203 GGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQD 382 GGKDGV LLWDL EGKRLYSLDAGSII++LCFSPNRYWLCAAT+ SIKIWDLESK IV+D Sbjct: 211 GGKDGVILLWDLAEGKRLYSLDAGSIIHALCFSPNRYWLCAATESSIKIWDLESKSIVED 270 Query: 383 LRPEV-----------PVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISGF 514 L+ ++ + K+++YCT L+WSADGSTL++GYTDG +R++ I + Sbjct: 271 LKVDLKTEADAAIGGDTTTKKKVIYCTSLNWSADGSTLFSGYTDGVVRVWGIGRY 325 Score = 57.4 bits (137), Expect = 3e-08 Identities = 44/164 (26%), Positives = 75/164 (45%), Gaps = 9/164 (5%) Frame = +2 Query: 44 SPNNFAPTIVSGSWDRSVKVWNLTNCKL-----RCTLDGHGGYVSAVAVSPDGSLCASGG 208 +P + + IV+ S D+S+ +W+LT R L GH +V V +S DG SG Sbjct: 23 TPIDNSDMIVTASRDKSIILWHLTKEDKTYGVPRRRLTGHSHFVQDVVLSSDGQFALSGS 82 Query: 209 KDGVTLLWDLTEG--KRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDL--ESKHIV 376 DG LWDL G R + +++ NR + A+ +IK+W+ E K+ + Sbjct: 83 WDGELRLWDLNAGTSARRFVGHTKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECKYTI 142 Query: 377 QDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 QD + + C S S T+ + D T++++ ++ Sbjct: 143 QD-----GDAHSDWVSCVRFSPSTPQPTIVSASWDRTVKVWNLT 181
>GBLP_CHLRE (P25387) Guanine nucleotide-binding protein beta subunit-like| protein Length = 318 Score = 259 bits (661), Expect = 5e-69 Identities = 121/167 (72%), Positives = 136/167 (81%), Gaps = 2/167 (1%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G T WVSCVRFSP P IVSG WD+ VKVWNLTNCKL+ L GH GYV+ V VSPDGS Sbjct: 148 GHTEWVSCVRFSPMTTNPIIVSGGWDKMVKVWNLTNCKLKNNLVGHHGYVNTVTVSPDGS 207 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKH 370 LCASGGKDG+ +LWDL EGKRLYSLDAG +I+ LCFSPNRYWLCAATQ SIKIWDLESK Sbjct: 208 LCASGGKDGIAMLWDLAEGKRLYSLDAGDVIHCLCFSPNRYWLCAATQSSIKIWDLESKS 267 Query: 371 IVQDLRPEVPVSSK--QMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 IV DLRPE ++SK Q+ YC L+WSADGSTLY+GYTDG IR++ + Sbjct: 268 IVDDLRPEFNITSKKAQVPYCVSLAWSADGSTLYSGYTDGQIRVWAV 314 Score = 65.1 bits (157), Expect = 1e-10 Identities = 44/176 (25%), Positives = 78/176 (44%), Gaps = 9/176 (5%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCK-----LRCTLDGHGGYVSAVA 172 +G T WV+ + + + T++S S D+SV VW L + R L GH +V V Sbjct: 12 KGHTNWVTAIATPLDPSSNTLLSASRDKSVLVWELERSESNYGYARKALRGHSHFVQDVV 71 Query: 173 VSPDGSLCASGGKDGVTLLWDLTEG--KRLYSLDAGSIINSLCFSPNRYWLCAATQDSIK 346 +S DG C +G DG LWDL G R + +++ NR + + +IK Sbjct: 72 ISSDGQFCLTGSWDGTLRLWDLNTGTTTRRFVGHTKDVLSVAFSVDNRQIVSGSRDKTIK 131 Query: 347 IWDL--ESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 +W+ E K+ + + P + + C S + +G D ++++ ++ Sbjct: 132 LWNTLGECKYTIGE-----PEGHTEWVSCVRFSPMTTNPIIVSGGWDKMVKVWNLT 182
>GBLP_SOYBN (Q39836) Guanine nucleotide-binding protein beta subunit-like| protein Length = 325 Score = 258 bits (659), Expect = 8e-69 Identities = 121/175 (69%), Positives = 142/175 (81%), Gaps = 11/175 (6%) Frame = +2 Query: 23 WVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCAS 202 WVSCVRFSP+ PTIVS SWDR+VKVWNLTNCKLR TL GH GYV+ VAVSPDGSLCAS Sbjct: 151 WVSCVRFSPSTLQPTIVSASWDRTVKVWNLTNCKLRNTLAGHNGYVNTVAVSPDGSLCAS 210 Query: 203 GGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQD 382 GGKDGV LLWDL EGKRLYSLDAGSII++LCFSP+RYWLCAAT+ SIKIWDLESK IV+D Sbjct: 211 GGKDGVILLWDLAEGKRLYSLDAGSIIHALCFSPSRYWLCAATEQSIKIWDLESKSIVED 270 Query: 383 LRPEVP-----------VSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISGF 514 L+ ++ + K+++YCT L+WSADGSTL++GYTDG R++ I + Sbjct: 271 LKVDLKTEADATSGGGNANKKKVIYCTSLNWSADGSTLFSGYTDGVARVWAIGRY 325 Score = 57.4 bits (137), Expect = 3e-08 Identities = 45/164 (27%), Positives = 75/164 (45%), Gaps = 9/164 (5%) Frame = +2 Query: 44 SPNNFAPTIVSGSWDRSVKVWNLTNCKL-----RCTLDGHGGYVSAVAVSPDGSLCASGG 208 +P + + IV+ S DRS+ +W+LT R L GH +V V +S DG SG Sbjct: 23 TPIDNSDMIVTASRDRSIILWHLTKEDKTYGVPRRRLTGHSHFVQDVVLSSDGQFALSGS 82 Query: 209 KDGVTLLWDLTEG--KRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDL--ESKHIV 376 DG LWDL G R + +++ NR + A+ +IK+W+ E K+ + Sbjct: 83 WDGELRLWDLAAGTSARRFVGHTKDVLSVAFSIDNRQIVSASRDRTIKLWNTLGECKYTI 142 Query: 377 QDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 QD + + C S S T+ + D T++++ ++ Sbjct: 143 QD-----GDAHSDWVSCVRFSPSTLQPTIVSASWDRTVKVWNLT 181
>GBLP_ARATH (O24456) Guanine nucleotide-binding protein beta subunit-like| protein (WD-40 repeat auxin-dependent protein ARCA) Length = 327 Score = 254 bits (650), Expect = 9e-68 Identities = 120/180 (66%), Positives = 144/180 (80%), Gaps = 12/180 (6%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G WVSCVRFSPN PTIVS SWD++VKVWNL+NCKLR TL GH GYVS VAVSPDGS Sbjct: 148 GHRDWVSCVRFSPNTLQPTIVSASWDKTVKVWNLSNCKLRSTLAGHTGYVSTVAVSPDGS 207 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKH 370 LCASGGKDGV LLWDL EGK+LYSL+A S+I++LCFSPNRYWLCAAT+ IKIWDLESK Sbjct: 208 LCASGGKDGVVLLWDLAEGKKLYSLEANSVIHALCFSPNRYWLCAATEHGIKIWDLESKS 267 Query: 371 IVQDLRPEV-----------PVSSK-QMLYCTCLSWSADGSTLYAGYTDGTIRIYKISGF 514 IV+DL+ ++ P ++K +++YCT L+WSADGSTL++GYTDG IR++ I + Sbjct: 268 IVEDLKVDLKAEAEKADNSGPAATKRKVIYCTSLNWSADGSTLFSGYTDGVIRVWGIGRY 327 Score = 55.5 bits (132), Expect = 1e-07 Identities = 47/176 (26%), Positives = 78/176 (44%), Gaps = 9/176 (5%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCK-----LRCTLDGHGGYVSAVA 172 R T V+ + +P + A IVS S D+S+ +W LT + L GH +V V Sbjct: 12 RAHTDMVTAIA-TPIDNADIIVSASRDKSIILWKLTKDDKAYGVAQRRLTGHSHFVEDVV 70 Query: 173 VSPDGSLCASGGKDGVTLLWDLTEG--KRLYSLDAGSIINSLCFSPNRYWLCAATQDSIK 346 +S DG SG DG LWDL G R + +++ NR + A+ +IK Sbjct: 71 LSSDGQFALSGSWDGELRLWDLAAGVSTRRFVGHTKDVLSVAFSLDNRQIVSASRDRTIK 130 Query: 347 IWDL--ESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 +W+ E K+ + E + + C S + T+ + D T++++ +S Sbjct: 131 LWNTLGECKYTIS----EGGEGHRDWVSCVRFSPNTLQPTIVSASWDKTVKVWNLS 182
>GBLP_BRANA (Q39336) Guanine nucleotide-binding protein beta subunit-like| protein Length = 327 Score = 248 bits (632), Expect = 1e-65 Identities = 115/180 (63%), Positives = 141/180 (78%), Gaps = 12/180 (6%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G WVSCVRFSPN PTIVS S D++VKVWNL+NCKLR TL GH GYVS VAVSPDGS Sbjct: 148 GHRDWVSCVRFSPNTLQPTIVSASCDKTVKVWNLSNCKLRSTLAGHTGYVSTVAVSPDGS 207 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKH 370 LCASGGKDGV LLWDL EGK+LYSL+A S+I++LCF+PNRYWLCAAT+ IKIWDLESK Sbjct: 208 LCASGGKDGVVLLWDLAEGKKLYSLEANSVIHALCFTPNRYWLCAATEQGIKIWDLESKT 267 Query: 371 IVQDLRPEV------------PVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISGF 514 +V+DL+ ++ + ++++YCT L+WSADGSTL++GYTDG IR++ I + Sbjct: 268 VVEDLKVDLKAEAEKSDGSGTAATKRKVIYCTSLNWSADGSTLFSGYTDGVIRVWGIGRY 327 Score = 57.8 bits (138), Expect = 2e-08 Identities = 48/176 (27%), Positives = 79/176 (44%), Gaps = 9/176 (5%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKL-----RCTLDGHGGYVSAVA 172 R T V+ + +P + + TIVS S D+S+ VW LT + L GH +V V Sbjct: 12 RAHTDMVTAIA-TPIDNSDTIVSASRDKSIIVWKLTKDDKSYGVRQRRLTGHSHFVEDVV 70 Query: 173 VSPDGSLCASGGKDGVTLLWDLTEG--KRLYSLDAGSIINSLCFSPNRYWLCAATQDSIK 346 +S DG SG DG LWDL G R + +++ NR + A+ +IK Sbjct: 71 LSSDGQFALSGSWDGELRLWDLAAGVSTRRFVGHTKDVLSVAFSLDNRQIVSASRDRTIK 130 Query: 347 IWDL--ESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 +W+ E K+ + E + + C S + T+ + D T++++ +S Sbjct: 131 LWNTLGECKYTIS----EGGEGHRDWVSCVRFSPNTLQPTIVSASCDKTVKVWNLS 182
>GBLP_ORENI (O42249) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C) (RACK) Length = 317 Score = 231 bits (589), Expect = 1e-60 Identities = 109/168 (64%), Positives = 128/168 (76%), Gaps = 2/168 (1%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G T WVSCVRFSPN+ P IVS WD+ VKVWNL NCKL+ GH GY++ V VSPDGS Sbjct: 146 GHTEWVSCVRFSPNSSNPIIVSCGWDKMVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGS 205 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKH 370 LCASGGKDG +LWDL EGK LY+LD+G +IN+LCFSPNRYWLCAAT SIKIWDLE K Sbjct: 206 LCASGGKDGQAMLWDLNEGKHLYTLDSGDVINALCFSPNRYWLCAATGPSIKIWDLEGKI 265 Query: 371 IVQDLRPEV--PVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 IV +LR EV S + CT L+WSADG TL+AGYTD IR+++++ Sbjct: 266 IVDELRQEVISTNSKAEPPQCTSLAWSADGQTLFAGYTDNLIRVWQVT 313 Score = 64.7 bits (156), Expect = 2e-10 Identities = 41/134 (30%), Positives = 67/134 (50%), Gaps = 9/134 (6%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRC-----TLDGHGGYVSAVA 172 +G +GWV+ + +P + I+S S D+S+ +W LT + +L GH +VS V Sbjct: 12 KGHSGWVTQIATTPK-YPDMILSASRDKSIIMWKLTRDETNYGIPQRSLKGHSHFVSDVV 70 Query: 173 VSPDGSLCASGGKDGVTLLWDLTEG--KRLYSLDAGSIINSLCFSPNRYWLCAATQDSIK 346 +S DG SG DG LWDLT G R + +++ + NR + + +IK Sbjct: 71 ISSDGQFALSGAWDGTLRLWDLTTGLTTRRFVGHTKDVLSVAFSADNRQIVSGSRDKTIK 130 Query: 347 IWDL--ESKHIVQD 382 +W+ K+ +QD Sbjct: 131 LWNTLGVCKYTIQD 144 Score = 43.1 bits (100), Expect = 5e-04 Identities = 33/137 (24%), Positives = 63/137 (45%), Gaps = 8/137 (5%) Frame = +2 Query: 125 LRCTLDGHGGYVSAVAVSPD-GSLCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCF- 298 +R TL GH G+V+ +A +P + S +D ++W LT + Y + S+ F Sbjct: 7 VRGTLKGHSGWVTQIATTPKYPDMILSASRDKSIIMWKLTRDETNYGIPQRSLKGHSHFV 66 Query: 299 ------SPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGST 460 S ++ L A ++++WDL + + +K +L +++SAD Sbjct: 67 SDVVISSDGQFALSGAWDGTLRLWDLTTGLTTR----RFVGHTKDVL---SVAFSADNRQ 119 Query: 461 LYAGYTDGTIRIYKISG 511 + +G D TI+++ G Sbjct: 120 IVSGSRDKTIKLWNTLG 136
>GBLP_RAT (P63245) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 316 Score = 227 bits (579), Expect = 2e-59 Identities = 108/164 (65%), Positives = 127/164 (77%), Gaps = 2/164 (1%) Frame = +2 Query: 23 WVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCAS 202 WVSCVRFSPN+ P IVS WD+ VKVWNL NCKL+ GH GY++ V VSPDGSLCAS Sbjct: 149 WVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCAS 208 Query: 203 GGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQD 382 GGKDG +LWDL EGK LY+LD G IIN+LCFSPNRYWLCAAT SIKIWDLE K IV + Sbjct: 209 GGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDE 268 Query: 383 LRPEV-PVSSK-QMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 L+ EV SSK + CT L+WSADG TL+AGYTD +R+++++ Sbjct: 269 LKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVT 312 Score = 65.1 bits (157), Expect = 1e-10 Identities = 43/134 (32%), Positives = 65/134 (48%), Gaps = 9/134 (6%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRC-----TLDGHGGYVSAVA 172 +G GWV+ + +P F I+S S D+++ +W LT + L GH +VS V Sbjct: 11 KGHNGWVTQIATTPQ-FPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVV 69 Query: 173 VSPDGSLCASGGKDGVTLLWDLTEG--KRLYSLDAGSIINSLCFSPNRYWLCAATQDSIK 346 +S DG SG DG LWDLT G R + +++ S NR + + +IK Sbjct: 70 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIK 129 Query: 347 IWDL--ESKHIVQD 382 +W+ K+ VQD Sbjct: 130 LWNTLGVCKYTVQD 143 Score = 47.0 bits (110), Expect = 4e-05 Identities = 47/174 (27%), Positives = 78/174 (44%), Gaps = 7/174 (4%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNN-FAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPD 184 RG + +VS V S + FA +SGSWD ++++W+LT GH V +VA S D Sbjct: 59 RGHSHFVSDVVISSDGQFA---LSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSD 115 Query: 185 GSLCASGGKDGVTLLWDLTEGKRLYSLDAGS---IINSLCFSPNR---YWLCAATQDSIK 346 SG +D LW+ T G Y++ S ++ + FSPN + +K Sbjct: 116 NRQIVSGSRDKTIKLWN-TLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVK 174 Query: 347 IWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 +W+L + + + Y ++ S DGS +G DG ++ ++ Sbjct: 175 VWNLANCKLKTN-------HIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLN 221 Score = 42.4 bits (98), Expect = 0.001 Identities = 31/137 (22%), Positives = 63/137 (45%), Gaps = 8/137 (5%) Frame = +2 Query: 125 LRCTLDGHGGYVSAVAVSPD-GSLCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCF- 298 LR TL GH G+V+ +A +P + S +D ++W LT + Y + ++ F Sbjct: 6 LRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFV 65 Query: 299 ------SPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGST 460 S ++ L + ++++WDL + + +K +L +++S+D Sbjct: 66 SDVVISSDGQFALSGSWDGTLRLWDLTTGTTTR----RFVGHTKDVL---SVAFSSDNRQ 118 Query: 461 LYAGYTDGTIRIYKISG 511 + +G D TI+++ G Sbjct: 119 IVSGSRDKTIKLWNTLG 135
>GBLP_PIG (P63246) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 316 Score = 227 bits (579), Expect = 2e-59 Identities = 108/164 (65%), Positives = 127/164 (77%), Gaps = 2/164 (1%) Frame = +2 Query: 23 WVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCAS 202 WVSCVRFSPN+ P IVS WD+ VKVWNL NCKL+ GH GY++ V VSPDGSLCAS Sbjct: 149 WVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCAS 208 Query: 203 GGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQD 382 GGKDG +LWDL EGK LY+LD G IIN+LCFSPNRYWLCAAT SIKIWDLE K IV + Sbjct: 209 GGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDE 268 Query: 383 LRPEV-PVSSK-QMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 L+ EV SSK + CT L+WSADG TL+AGYTD +R+++++ Sbjct: 269 LKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVT 312 Score = 65.1 bits (157), Expect = 1e-10 Identities = 43/134 (32%), Positives = 65/134 (48%), Gaps = 9/134 (6%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRC-----TLDGHGGYVSAVA 172 +G GWV+ + +P F I+S S D+++ +W LT + L GH +VS V Sbjct: 11 KGHNGWVTQIATTPQ-FPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVV 69 Query: 173 VSPDGSLCASGGKDGVTLLWDLTEG--KRLYSLDAGSIINSLCFSPNRYWLCAATQDSIK 346 +S DG SG DG LWDLT G R + +++ S NR + + +IK Sbjct: 70 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIK 129 Query: 347 IWDL--ESKHIVQD 382 +W+ K+ VQD Sbjct: 130 LWNTLGVCKYTVQD 143 Score = 47.0 bits (110), Expect = 4e-05 Identities = 47/174 (27%), Positives = 78/174 (44%), Gaps = 7/174 (4%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNN-FAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPD 184 RG + +VS V S + FA +SGSWD ++++W+LT GH V +VA S D Sbjct: 59 RGHSHFVSDVVISSDGQFA---LSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSD 115 Query: 185 GSLCASGGKDGVTLLWDLTEGKRLYSLDAGS---IINSLCFSPNR---YWLCAATQDSIK 346 SG +D LW+ T G Y++ S ++ + FSPN + +K Sbjct: 116 NRQIVSGSRDKTIKLWN-TLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVK 174 Query: 347 IWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 +W+L + + + Y ++ S DGS +G DG ++ ++ Sbjct: 175 VWNLANCKLKTN-------HIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLN 221 Score = 42.4 bits (98), Expect = 0.001 Identities = 31/137 (22%), Positives = 63/137 (45%), Gaps = 8/137 (5%) Frame = +2 Query: 125 LRCTLDGHGGYVSAVAVSPD-GSLCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCF- 298 LR TL GH G+V+ +A +P + S +D ++W LT + Y + ++ F Sbjct: 6 LRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFV 65 Query: 299 ------SPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGST 460 S ++ L + ++++WDL + + +K +L +++S+D Sbjct: 66 SDVVISSDGQFALSGSWDGTLRLWDLTTGTTTR----RFVGHTKDVL---SVAFSSDNRQ 118 Query: 461 LYAGYTDGTIRIYKISG 511 + +G D TI+++ G Sbjct: 119 IVSGSRDKTIKLWNTLG 135
>GBLP_MOUSE (P68040) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) (p205) (12-3) Length = 316 Score = 227 bits (579), Expect = 2e-59 Identities = 108/164 (65%), Positives = 127/164 (77%), Gaps = 2/164 (1%) Frame = +2 Query: 23 WVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCAS 202 WVSCVRFSPN+ P IVS WD+ VKVWNL NCKL+ GH GY++ V VSPDGSLCAS Sbjct: 149 WVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCAS 208 Query: 203 GGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQD 382 GGKDG +LWDL EGK LY+LD G IIN+LCFSPNRYWLCAAT SIKIWDLE K IV + Sbjct: 209 GGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDE 268 Query: 383 LRPEV-PVSSK-QMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 L+ EV SSK + CT L+WSADG TL+AGYTD +R+++++ Sbjct: 269 LKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVT 312 Score = 65.1 bits (157), Expect = 1e-10 Identities = 43/134 (32%), Positives = 65/134 (48%), Gaps = 9/134 (6%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRC-----TLDGHGGYVSAVA 172 +G GWV+ + +P F I+S S D+++ +W LT + L GH +VS V Sbjct: 11 KGHNGWVTQIATTPQ-FPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVV 69 Query: 173 VSPDGSLCASGGKDGVTLLWDLTEG--KRLYSLDAGSIINSLCFSPNRYWLCAATQDSIK 346 +S DG SG DG LWDLT G R + +++ S NR + + +IK Sbjct: 70 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIK 129 Query: 347 IWDL--ESKHIVQD 382 +W+ K+ VQD Sbjct: 130 LWNTLGVCKYTVQD 143 Score = 47.0 bits (110), Expect = 4e-05 Identities = 47/174 (27%), Positives = 78/174 (44%), Gaps = 7/174 (4%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNN-FAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPD 184 RG + +VS V S + FA +SGSWD ++++W+LT GH V +VA S D Sbjct: 59 RGHSHFVSDVVISSDGQFA---LSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSD 115 Query: 185 GSLCASGGKDGVTLLWDLTEGKRLYSLDAGS---IINSLCFSPNR---YWLCAATQDSIK 346 SG +D LW+ T G Y++ S ++ + FSPN + +K Sbjct: 116 NRQIVSGSRDKTIKLWN-TLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVK 174 Query: 347 IWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 +W+L + + + Y ++ S DGS +G DG ++ ++ Sbjct: 175 VWNLANCKLKTN-------HIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLN 221 Score = 42.4 bits (98), Expect = 0.001 Identities = 31/137 (22%), Positives = 63/137 (45%), Gaps = 8/137 (5%) Frame = +2 Query: 125 LRCTLDGHGGYVSAVAVSPD-GSLCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCF- 298 LR TL GH G+V+ +A +P + S +D ++W LT + Y + ++ F Sbjct: 6 LRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFV 65 Query: 299 ------SPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGST 460 S ++ L + ++++WDL + + +K +L +++S+D Sbjct: 66 SDVVISSDGQFALSGSWDGTLRLWDLTTGTTTR----RFVGHTKDVL---SVAFSSDNRQ 118 Query: 461 LYAGYTDGTIRIYKISG 511 + +G D TI+++ G Sbjct: 119 IVSGSRDKTIKLWNTLG 135
>GBLP_MACFA (Q4R7Y4) Guanine nucleotide-binding protein beta subunit 2-like 1| Length = 316 Score = 227 bits (579), Expect = 2e-59 Identities = 108/164 (65%), Positives = 127/164 (77%), Gaps = 2/164 (1%) Frame = +2 Query: 23 WVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCAS 202 WVSCVRFSPN+ P IVS WD+ VKVWNL NCKL+ GH GY++ V VSPDGSLCAS Sbjct: 149 WVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCAS 208 Query: 203 GGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQD 382 GGKDG +LWDL EGK LY+LD G IIN+LCFSPNRYWLCAAT SIKIWDLE K IV + Sbjct: 209 GGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDE 268 Query: 383 LRPEV-PVSSK-QMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 L+ EV SSK + CT L+WSADG TL+AGYTD +R+++++ Sbjct: 269 LKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVT 312 Score = 65.1 bits (157), Expect = 1e-10 Identities = 43/134 (32%), Positives = 65/134 (48%), Gaps = 9/134 (6%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRC-----TLDGHGGYVSAVA 172 +G GWV+ + +P F I+S S D+++ +W LT + L GH +VS V Sbjct: 11 KGHNGWVTQIATTPQ-FPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVV 69 Query: 173 VSPDGSLCASGGKDGVTLLWDLTEG--KRLYSLDAGSIINSLCFSPNRYWLCAATQDSIK 346 +S DG SG DG LWDLT G R + +++ S NR + + +IK Sbjct: 70 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIK 129 Query: 347 IWDL--ESKHIVQD 382 +W+ K+ VQD Sbjct: 130 LWNTLGVCKYTVQD 143 Score = 47.0 bits (110), Expect = 4e-05 Identities = 47/174 (27%), Positives = 78/174 (44%), Gaps = 7/174 (4%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNN-FAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPD 184 RG + +VS V S + FA +SGSWD ++++W+LT GH V +VA S D Sbjct: 59 RGHSHFVSDVVISSDGQFA---LSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSD 115 Query: 185 GSLCASGGKDGVTLLWDLTEGKRLYSLDAGS---IINSLCFSPNR---YWLCAATQDSIK 346 SG +D LW+ T G Y++ S ++ + FSPN + +K Sbjct: 116 NRQIVSGSRDKTIKLWN-TLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVK 174 Query: 347 IWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 +W+L + + + Y ++ S DGS +G DG ++ ++ Sbjct: 175 VWNLANCKLKTN-------HIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLN 221 Score = 42.4 bits (98), Expect = 0.001 Identities = 31/137 (22%), Positives = 63/137 (45%), Gaps = 8/137 (5%) Frame = +2 Query: 125 LRCTLDGHGGYVSAVAVSPD-GSLCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCF- 298 LR TL GH G+V+ +A +P + S +D ++W LT + Y + ++ F Sbjct: 6 LRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFV 65 Query: 299 ------SPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGST 460 S ++ L + ++++WDL + + +K +L +++S+D Sbjct: 66 SDVVISSDGQFALSGSWDGTLRLWDLTTGTTTR----RFVGHTKDVL---SVAFSSDNRQ 118 Query: 461 LYAGYTDGTIRIYKISG 511 + +G D TI+++ G Sbjct: 119 IVSGSRDKTIKLWNTLG 135
>GBLP_HUMAN (P63244) Guanine nucleotide-binding protein beta subunit 2-like 1| (Guanine nucleotide-binding protein beta subunit-like protein 12.3) (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 316 Score = 227 bits (579), Expect = 2e-59 Identities = 108/164 (65%), Positives = 127/164 (77%), Gaps = 2/164 (1%) Frame = +2 Query: 23 WVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCAS 202 WVSCVRFSPN+ P IVS WD+ VKVWNL NCKL+ GH GY++ V VSPDGSLCAS Sbjct: 149 WVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCAS 208 Query: 203 GGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQD 382 GGKDG +LWDL EGK LY+LD G IIN+LCFSPNRYWLCAAT SIKIWDLE K IV + Sbjct: 209 GGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDE 268 Query: 383 LRPEV-PVSSK-QMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 L+ EV SSK + CT L+WSADG TL+AGYTD +R+++++ Sbjct: 269 LKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVT 312 Score = 65.1 bits (157), Expect = 1e-10 Identities = 43/134 (32%), Positives = 65/134 (48%), Gaps = 9/134 (6%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRC-----TLDGHGGYVSAVA 172 +G GWV+ + +P F I+S S D+++ +W LT + L GH +VS V Sbjct: 11 KGHNGWVTQIATTPQ-FPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVV 69 Query: 173 VSPDGSLCASGGKDGVTLLWDLTEG--KRLYSLDAGSIINSLCFSPNRYWLCAATQDSIK 346 +S DG SG DG LWDLT G R + +++ S NR + + +IK Sbjct: 70 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIK 129 Query: 347 IWDL--ESKHIVQD 382 +W+ K+ VQD Sbjct: 130 LWNTLGVCKYTVQD 143 Score = 47.0 bits (110), Expect = 4e-05 Identities = 47/174 (27%), Positives = 78/174 (44%), Gaps = 7/174 (4%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNN-FAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPD 184 RG + +VS V S + FA +SGSWD ++++W+LT GH V +VA S D Sbjct: 59 RGHSHFVSDVVISSDGQFA---LSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSD 115 Query: 185 GSLCASGGKDGVTLLWDLTEGKRLYSLDAGS---IINSLCFSPNR---YWLCAATQDSIK 346 SG +D LW+ T G Y++ S ++ + FSPN + +K Sbjct: 116 NRQIVSGSRDKTIKLWN-TLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVK 174 Query: 347 IWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 +W+L + + + Y ++ S DGS +G DG ++ ++ Sbjct: 175 VWNLANCKLKTN-------HIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLN 221 Score = 42.4 bits (98), Expect = 0.001 Identities = 31/137 (22%), Positives = 63/137 (45%), Gaps = 8/137 (5%) Frame = +2 Query: 125 LRCTLDGHGGYVSAVAVSPD-GSLCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCF- 298 LR TL GH G+V+ +A +P + S +D ++W LT + Y + ++ F Sbjct: 6 LRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFV 65 Query: 299 ------SPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGST 460 S ++ L + ++++WDL + + +K +L +++S+D Sbjct: 66 SDVVISSDGQFALSGSWDGTLRLWDLTTGTTTR----RFVGHTKDVL---SVAFSSDNRQ 118 Query: 461 LYAGYTDGTIRIYKISG 511 + +G D TI+++ G Sbjct: 119 IVSGSRDKTIKLWNTLG 135
>GBLP_BOVIN (P63243) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 316 Score = 227 bits (579), Expect = 2e-59 Identities = 108/164 (65%), Positives = 127/164 (77%), Gaps = 2/164 (1%) Frame = +2 Query: 23 WVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCAS 202 WVSCVRFSPN+ P IVS WD+ VKVWNL NCKL+ GH GY++ V VSPDGSLCAS Sbjct: 149 WVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCAS 208 Query: 203 GGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQD 382 GGKDG +LWDL EGK LY+LD G IIN+LCFSPNRYWLCAAT SIKIWDLE K IV + Sbjct: 209 GGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDE 268 Query: 383 LRPEV-PVSSK-QMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 L+ EV SSK + CT L+WSADG TL+AGYTD +R+++++ Sbjct: 269 LKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVT 312 Score = 65.1 bits (157), Expect = 1e-10 Identities = 43/134 (32%), Positives = 65/134 (48%), Gaps = 9/134 (6%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRC-----TLDGHGGYVSAVA 172 +G GWV+ + +P F I+S S D+++ +W LT + L GH +VS V Sbjct: 11 KGHNGWVTQIATTPQ-FPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVV 69 Query: 173 VSPDGSLCASGGKDGVTLLWDLTEG--KRLYSLDAGSIINSLCFSPNRYWLCAATQDSIK 346 +S DG SG DG LWDLT G R + +++ S NR + + +IK Sbjct: 70 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIK 129 Query: 347 IWDL--ESKHIVQD 382 +W+ K+ VQD Sbjct: 130 LWNTLGVCKYTVQD 143 Score = 47.0 bits (110), Expect = 4e-05 Identities = 47/174 (27%), Positives = 78/174 (44%), Gaps = 7/174 (4%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNN-FAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPD 184 RG + +VS V S + FA +SGSWD ++++W+LT GH V +VA S D Sbjct: 59 RGHSHFVSDVVISSDGQFA---LSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSD 115 Query: 185 GSLCASGGKDGVTLLWDLTEGKRLYSLDAGS---IINSLCFSPNR---YWLCAATQDSIK 346 SG +D LW+ T G Y++ S ++ + FSPN + +K Sbjct: 116 NRQIVSGSRDKTIKLWN-TLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVK 174 Query: 347 IWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 +W+L + + + Y ++ S DGS +G DG ++ ++ Sbjct: 175 VWNLANCKLKTN-------HIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLN 221 Score = 42.4 bits (98), Expect = 0.001 Identities = 31/137 (22%), Positives = 63/137 (45%), Gaps = 8/137 (5%) Frame = +2 Query: 125 LRCTLDGHGGYVSAVAVSPD-GSLCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCF- 298 LR TL GH G+V+ +A +P + S +D ++W LT + Y + ++ F Sbjct: 6 LRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFV 65 Query: 299 ------SPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGST 460 S ++ L + ++++WDL + + +K +L +++S+D Sbjct: 66 SDVVISSDGQFALSGSWDGTLRLWDLTTGTTTR----RFVGHTKDVL---SVAFSSDNRQ 118 Query: 461 LYAGYTDGTIRIYKISG 511 + +G D TI+++ G Sbjct: 119 IVSGSRDKTIKLWNTLG 135
>GBLP_CHICK (P63247) Guanine nucleotide-binding protein beta subunit 2-like 1| (Guanine nucleotide-binding protein beta subunit-like protein 12.3) (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 317 Score = 227 bits (579), Expect = 2e-59 Identities = 108/164 (65%), Positives = 127/164 (77%), Gaps = 2/164 (1%) Frame = +2 Query: 23 WVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCAS 202 WVSCVRFSPN+ P IVS WD+ VKVWNL NCKL+ GH GY++ V VSPDGSLCAS Sbjct: 150 WVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCAS 209 Query: 203 GGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQD 382 GGKDG +LWDL EGK LY+LD G IIN+LCFSPNRYWLCAAT SIKIWDLE K IV + Sbjct: 210 GGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDE 269 Query: 383 LRPEV-PVSSK-QMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 L+ EV SSK + CT L+WSADG TL+AGYTD +R+++++ Sbjct: 270 LKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVT 313 Score = 65.1 bits (157), Expect = 1e-10 Identities = 43/134 (32%), Positives = 65/134 (48%), Gaps = 9/134 (6%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRC-----TLDGHGGYVSAVA 172 +G GWV+ + +P F I+S S D+++ +W LT + L GH +VS V Sbjct: 12 KGHNGWVTQIATTPQ-FPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVV 70 Query: 173 VSPDGSLCASGGKDGVTLLWDLTEG--KRLYSLDAGSIINSLCFSPNRYWLCAATQDSIK 346 +S DG SG DG LWDLT G R + +++ S NR + + +IK Sbjct: 71 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIK 130 Query: 347 IWDL--ESKHIVQD 382 +W+ K+ VQD Sbjct: 131 LWNTLGVCKYTVQD 144 Score = 47.0 bits (110), Expect = 4e-05 Identities = 47/174 (27%), Positives = 78/174 (44%), Gaps = 7/174 (4%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNN-FAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPD 184 RG + +VS V S + FA +SGSWD ++++W+LT GH V +VA S D Sbjct: 60 RGHSHFVSDVVISSDGQFA---LSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSD 116 Query: 185 GSLCASGGKDGVTLLWDLTEGKRLYSLDAGS---IINSLCFSPNR---YWLCAATQDSIK 346 SG +D LW+ T G Y++ S ++ + FSPN + +K Sbjct: 117 NRQIVSGSRDKTIKLWN-TLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVK 175 Query: 347 IWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 +W+L + + + Y ++ S DGS +G DG ++ ++ Sbjct: 176 VWNLANCKLKTN-------HIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLN 222 Score = 42.4 bits (98), Expect = 0.001 Identities = 31/137 (22%), Positives = 63/137 (45%), Gaps = 8/137 (5%) Frame = +2 Query: 125 LRCTLDGHGGYVSAVAVSPD-GSLCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCF- 298 LR TL GH G+V+ +A +P + S +D ++W LT + Y + ++ F Sbjct: 7 LRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFV 66 Query: 299 ------SPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGST 460 S ++ L + ++++WDL + + +K +L +++S+D Sbjct: 67 SDVVISSDGQFALSGSWDGTLRLWDLTTGTTTR----RFVGHTKDVL---SVAFSSDNRQ 119 Query: 461 LYAGYTDGTIRIYKISG 511 + +G D TI+++ G Sbjct: 120 IVSGSRDKTIKLWNTLG 136
>GBLP_BRARE (O42248) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C) (RACK) Length = 317 Score = 226 bits (577), Expect = 3e-59 Identities = 106/166 (63%), Positives = 125/166 (75%), Gaps = 2/166 (1%) Frame = +2 Query: 17 TGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLC 196 T WVSCVRFSPN+ P IVS WD+ VKVWNL NCKL+ GH GY++ V VSPDGSLC Sbjct: 148 TEWVSCVRFSPNSSNPIIVSCGWDKMVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLC 207 Query: 197 ASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIV 376 ASGGKDG +LWDL EGK LY+LD G IN+LCFSPNRYWLCAAT SIKIWDLE K IV Sbjct: 208 ASGGKDGQAMLWDLNEGKHLYTLDGGDTINALCFSPNRYWLCAATGPSIKIWDLEGKIIV 267 Query: 377 QDLRPEVPV--SSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 +LR ++ S + CT L+WSADG TL+AGYTD IR+++++ Sbjct: 268 DELRQDIITTNSKAEPPQCTSLAWSADGQTLFAGYTDNLIRVWQVT 313 Score = 63.9 bits (154), Expect = 3e-10 Identities = 41/134 (30%), Positives = 66/134 (49%), Gaps = 9/134 (6%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRC-----TLDGHGGYVSAVA 172 +G +GWV+ + +P F I+S S D+++ +W LT + L GH +VS V Sbjct: 12 KGHSGWVTQIATTPQ-FPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVV 70 Query: 173 VSPDGSLCASGGKDGVTLLWDLTEG--KRLYSLDAGSIINSLCFSPNRYWLCAATQDSIK 346 +S DG SG DG LWDLT G R + +++ + NR + + +IK Sbjct: 71 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSADNRQIVSGSRDKTIK 130 Query: 347 IWDL--ESKHIVQD 382 +W+ K+ +QD Sbjct: 131 LWNTLGVCKYTIQD 144 Score = 48.1 bits (113), Expect = 2e-05 Identities = 47/174 (27%), Positives = 78/174 (44%), Gaps = 7/174 (4%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNN-FAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPD 184 RG + +VS V S + FA +SGSWD ++++W+LT GH V +VA S D Sbjct: 60 RGHSHFVSDVVISSDGQFA---LSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSAD 116 Query: 185 GSLCASGGKDGVTLLWDLTEGKRLYSLDAGS---IINSLCFSPNR---YWLCAATQDSIK 346 SG +D LW+ T G Y++ S ++ + FSPN + +K Sbjct: 117 NRQIVSGSRDKTIKLWN-TLGVCKYTIQDDSHTEWVSCVRFSPNSSNPIIVSCGWDKMVK 175 Query: 347 IWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 +W+L + + + Y ++ S DGS +G DG ++ ++ Sbjct: 176 VWNLANCKLKTN-------HIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLN 222 Score = 42.4 bits (98), Expect = 0.001 Identities = 31/137 (22%), Positives = 63/137 (45%), Gaps = 8/137 (5%) Frame = +2 Query: 125 LRCTLDGHGGYVSAVAVSPD-GSLCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCF- 298 +R TL GH G+V+ +A +P + S +D ++W LT + Y + ++ F Sbjct: 7 VRGTLKGHSGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFV 66 Query: 299 ------SPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGST 460 S ++ L + ++++WDL + + +K +L +++SAD Sbjct: 67 SDVVISSDGQFALSGSWDGTLRLWDLTTGTTTR----RFVGHTKDVL---SVAFSADNRQ 119 Query: 461 LYAGYTDGTIRIYKISG 511 + +G D TI+++ G Sbjct: 120 IVSGSRDKTIKLWNTLG 136
>GBLP_HYDAT (Q25189) Guanine nucleotide-binding protein beta subunit-like| protein (Receptor of activated protein kinase C) (RACK) Length = 317 Score = 226 bits (576), Expect = 3e-59 Identities = 106/164 (64%), Positives = 128/164 (78%), Gaps = 2/164 (1%) Frame = +2 Query: 23 WVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCAS 202 WVSCVRFSPN P IVS WD+ VKVWNLTNCKL+ GH GY++AV VSPDGSLCAS Sbjct: 150 WVSCVRFSPNTQNPIIVSCGWDKMVKVWNLTNCKLKTNHFGHTGYLNAVTVSPDGSLCAS 209 Query: 203 GGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQD 382 GGKDG +LWDL EGK LY+LD G++IN+LCFSPNRYWLCAAT IKIWDLE K +V + Sbjct: 210 GGKDGNAMLWDLNEGKHLYTLDGGNVINALCFSPNRYWLCAATGPMIKIWDLEMKSVVDE 269 Query: 383 LRPEV-PVSSK-QMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 L+P V +S+K + C L+WSADG TL+AGYTD IR+++++ Sbjct: 270 LKPGVIGISTKSRAADCISLAWSADGQTLFAGYTDNLIRVWQVT 313 Score = 53.9 bits (128), Expect = 3e-07 Identities = 38/136 (27%), Positives = 65/136 (47%), Gaps = 11/136 (8%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTN-------CKLRCTLDGHGGYVSA 166 +G GWV+ + +P N I+S S D+++ W LT +C L GH +VS Sbjct: 11 KGHNGWVTQIATTPQN-PDLILSASRDKTLIQWQLTRDDQTNYGFPKKC-LTGHNHFVSD 68 Query: 167 VAVSPDGSLCASGGKDGVTLLWDLTEG--KRLYSLDAGSIINSLCFSPNRYWLCAATQDS 340 V +S DG S D LWDL +G + + +++ + NR + + ++ Sbjct: 69 VVLSSDGQFALSCSWDKTLRLWDLNQGITTKQFVGHTKDVLSVAFSADNRQIVSGSRDNT 128 Query: 341 IKIWDL--ESKHIVQD 382 IK+W+ + K+ +QD Sbjct: 129 IKLWNTLGQCKYTIQD 144 Score = 44.7 bits (104), Expect = 2e-04 Identities = 37/152 (24%), Positives = 67/152 (44%), Gaps = 6/152 (3%) Frame = +2 Query: 71 VSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGK 250 +S SWD+++++W+L GH V +VA S D SG +D LW+ T G+ Sbjct: 79 LSCSWDKTLRLWDLNQGITTKQFVGHTKDVLSVAFSADNRQIVSGSRDNTIKLWN-TLGQ 137 Query: 251 RLYSLDAGS---IINSLCFSPNR---YWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSK 412 Y++ S ++ + FSPN + +K+W+L + + + Sbjct: 138 CKYTIQDESHSEWVSCVRFSPNTQNPIIVSCGWDKMVKVWNLTNCKLKTN-------HFG 190 Query: 413 QMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 Y ++ S DGS +G DG ++ ++ Sbjct: 191 HTGYLNAVTVSPDGSLCASGGKDGNAMLWDLN 222 Score = 42.7 bits (99), Expect = 7e-04 Identities = 33/142 (23%), Positives = 63/142 (44%), Gaps = 13/142 (9%) Frame = +2 Query: 125 LRCTLDGHGGYVSAVAVSPDG-SLCASGGKDGVTLLWDLTEG--------KRLYSLDAGS 277 LR TL GH G+V+ +A +P L S +D + W LT K+ + Sbjct: 6 LRGTLKGHNGWVTQIATTPQNPDLILSASRDKTLIQWQLTRDDQTNYGFPKKCLTGHNHF 65 Query: 278 IINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCT----CLSWS 445 + + + S ++ L + ++++WDL +++KQ + T +++S Sbjct: 66 VSDVVLSSDGQFALSCSWDKTLRLWDLNQ-----------GITTKQFVGHTKDVLSVAFS 114 Query: 446 ADGSTLYAGYTDGTIRIYKISG 511 AD + +G D TI+++ G Sbjct: 115 ADNRQIVSGSRDNTIKLWNTLG 136
>GBLP_BIOGL (Q93134) Guanine nucleotide-binding protein beta subunit 2-like 1| (Receptor of activated protein kinase C) (RACK) Length = 316 Score = 226 bits (575), Expect = 4e-59 Identities = 106/165 (64%), Positives = 124/165 (75%), Gaps = 1/165 (0%) Frame = +2 Query: 17 TGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLC 196 T W SCVRFSPN P IVS WDR VKVWNLTNCKL+ GH GYV+ V VSPDGSLC Sbjct: 148 TDWTSCVRFSPNTQNPIIVSSGWDRLVKVWNLTNCKLKTNHYGHTGYVNTVTVSPDGSLC 207 Query: 197 ASGGKDGVTLLWDLTEGKRLYSLD-AGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHI 373 ASGGKD +LWDL EGK LY+LD AG IN+LCFSPNRYWLC A+ SIKIWDLE K + Sbjct: 208 ASGGKDSQAMLWDLNEGKHLYTLDGAGDTINALCFSPNRYWLCVASGPSIKIWDLEGKVV 267 Query: 374 VQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 V +L+PEV ++ + C L+WSADG TL+AGYTD IR++++S Sbjct: 268 VDELKPEVMGTTSKAPTCLSLAWSADGQTLFAGYTDKLIRVWQVS 312 Score = 60.5 bits (145), Expect = 3e-09 Identities = 41/134 (30%), Positives = 68/134 (50%), Gaps = 9/134 (6%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKL-----RCTLDGHGGYVSAVA 172 +G GWV+ + +P + I+S S D+S+ VW LT + + +L GHG +VS V Sbjct: 12 QGHGGWVTQIATTPQ-YPDMILSASRDKSLIVWRLTRDESSYGVPQKSLHGHGHFVSDVI 70 Query: 173 VSPDGSLCASGGKDGVTLLWDLTEGK--RLYSLDAGSIINSLCFSPNRYWLCAATQDSIK 346 +S DG SG D LWDL+ G+ R + +++ + NR + + +IK Sbjct: 71 LSSDGQFALSGSWDHTLRLWDLSTGQTTRRFVGHTKDVLSVAFSADNRQIVSGSRDKTIK 130 Query: 347 IWDL--ESKHIVQD 382 +W+ K+ +QD Sbjct: 131 LWNTLGVCKYTIQD 144 Score = 47.0 bits (110), Expect = 4e-05 Identities = 33/137 (24%), Positives = 65/137 (47%), Gaps = 8/137 (5%) Frame = +2 Query: 125 LRCTLDGHGGYVSAVAVSPD-GSLCASGGKDGVTLLWDLTEGKRLYSLDAGS-------I 280 LR TL GHGG+V+ +A +P + S +D ++W LT + Y + S + Sbjct: 7 LRGTLQGHGGWVTQIATTPQYPDMILSASRDKSLIVWRLTRDESSYGVPQKSLHGHGHFV 66 Query: 281 INSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGST 460 + + S ++ L + ++++WDL + + +K +L +++SAD Sbjct: 67 SDVILSSDGQFALSGSWDHTLRLWDLSTGQTTR----RFVGHTKDVL---SVAFSADNRQ 119 Query: 461 LYAGYTDGTIRIYKISG 511 + +G D TI+++ G Sbjct: 120 IVSGSRDKTIKLWNTLG 136 Score = 41.6 bits (96), Expect = 0.002 Identities = 29/102 (28%), Positives = 49/102 (48%), Gaps = 6/102 (5%) Frame = +2 Query: 71 VSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGK 250 +SGSWD ++++W+L+ + GH V +VA S D SG +D LW+ T G Sbjct: 79 LSGSWDHTLRLWDLSTGQTTRRFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWN-TLGV 137 Query: 251 RLYSLDAG---SIINSLCFSPNR---YWLCAATQDSIKIWDL 358 Y++ + + FSPN + + +K+W+L Sbjct: 138 CKYTIQDDCHTDWTSCVRFSPNTQNPIIVSSGWDRLVKVWNL 179
>GBLP_DROME (O18640) Guanine nucleotide-binding protein beta subunit-like| protein (Receptor of activated protein kinase C homolog) Length = 318 Score = 223 bits (569), Expect = 2e-58 Identities = 104/168 (61%), Positives = 122/168 (72%), Gaps = 2/168 (1%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G T WVSCVRFSPN+ P IVS WDR+VKVWNL NCKL+ GH GY++ V VSPDGS Sbjct: 147 GHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANCKLKNNHHGHNGYLNTVTVSPDGS 206 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKH 370 LC SGGKD LLWDL +GK LY+L+ IIN+LCFSPNRYWLC A SIKIWDL K Sbjct: 207 LCTSGGKDSKALLWDLNDGKNLYTLEHNDIINALCFSPNRYWLCVAYGPSIKIWDLACKK 266 Query: 371 IVQDLRPEV--PVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 V++LRPEV P S C L+WS DG TL+AGY+D TIR++++S Sbjct: 267 TVEELRPEVVSPTSKADQPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 314 Score = 59.3 bits (142), Expect = 7e-09 Identities = 40/134 (29%), Positives = 66/134 (49%), Gaps = 10/134 (7%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCK------LRCTLDGHGGYVSAVA 172 G GWV+ + +P + TI+S S D+++ VW LT + + L GH ++S V Sbjct: 13 GHNGWVTQIATNPKD-PDTIISASRDKTLIVWKLTRDEDTNYGYPQKRLYGHSHFISDVV 71 Query: 173 VSPDGSLCASGGKDGVTLLWDLTEGK--RLYSLDAGSIINSLCFSPNRYWLCAATQDSIK 346 +S DG+ SG D LWDL GK R + +++ + NR + + +IK Sbjct: 72 LSSDGNYALSGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIK 131 Query: 347 IWD--LESKHIVQD 382 +W+ E K +Q+ Sbjct: 132 LWNTLAECKFTIQE 145 Score = 48.5 bits (114), Expect = 1e-05 Identities = 34/110 (30%), Positives = 55/110 (50%), Gaps = 5/110 (4%) Frame = +2 Query: 44 SPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVT 223 S N+A +SGSWD+++++W+L K +GH V +VA S D SG +D Sbjct: 74 SDGNYA---LSGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTI 130 Query: 224 LLWD-LTEGKRLYSLDAGS-IINSLCFSPNR---YWLCAATQDSIKIWDL 358 LW+ L E K D + ++ + FSPN + ++K+W+L Sbjct: 131 KLWNTLAECKFTIQEDGHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNL 180 Score = 45.8 bits (107), Expect = 8e-05 Identities = 36/136 (26%), Positives = 64/136 (47%), Gaps = 10/136 (7%) Frame = +2 Query: 122 KLRCTLDGHGGYVSAVAVSP-DGSLCASGGKDGVTLLWDLTEG---------KRLYSLDA 271 +LR TL GH G+V+ +A +P D S +D ++W LT KRLY + Sbjct: 6 QLRGTLIGHNGWVTQIATNPKDPDTIISASRDKTLIVWKLTRDEDTNYGYPQKRLYG-HS 64 Query: 272 GSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSAD 451 I + + S Y L + ++++WDL + + +K +L +++SAD Sbjct: 65 HFISDVVLSSDGNYALSGSWDQTLRLWDLAAGKTTRRFEGH----TKDVL---SVAFSAD 117 Query: 452 GSTLYAGYTDGTIRIY 499 + +G D TI+++ Sbjct: 118 NRQIVSGSRDKTIKLW 133
>GBLP_CAEEL (Q21215) Guanine nucleotide-binding protein beta subunit 2-like 1| Length = 324 Score = 213 bits (543), Expect = 2e-55 Identities = 99/167 (59%), Positives = 119/167 (71%), Gaps = 3/167 (1%) Frame = +2 Query: 17 TGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLC 196 T WVS VRFSP+N P IVS WD+ VKVWNL NC+L+ GH GYV+ V VSPDGSLC Sbjct: 153 TDWVSTVRFSPSNRDPVIVSAGWDKVVKVWNLGNCRLKTNHIGHTGYVNTVTVSPDGSLC 212 Query: 197 ASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIV 376 ASGGKDG +LWDL EGK LY+L +IN++ FSPNRYWLCAA SIKIWDLE K + Sbjct: 213 ASGGKDGQAMLWDLNEGKHLYTLPGNDVINAMSFSPNRYWLCAAVGSSIKIWDLEDKKEI 272 Query: 377 QDLRPEVPVSSK---QMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 ++L+PE+ S C L+WS DG TL+AGYTD IR+Y++S Sbjct: 273 EELKPEIASSGSSRGSSPQCISLAWSQDGQTLFAGYTDNIIRVYQVS 319 Score = 60.1 bits (144), Expect = 4e-09 Identities = 38/137 (27%), Positives = 65/137 (47%), Gaps = 13/137 (9%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNC---------KLRCTLDGHGGYVS 163 G TGWV+ + N T++S S D+++ VW++ + + +L GH +VS Sbjct: 13 GHTGWVTQIATYTRNDKTTVLSSSRDKTILVWDVDSVAPVDEGPIGRPVRSLTGHNHFVS 72 Query: 164 AVAVSPDGSLCASGGKDGVTLLWDLTEG--KRLYSLDAGSIINSLCFSPNRYWLCAATQD 337 V +S DG SG D LWDL +G R + +++ + NR + + Sbjct: 73 DVVISSDGQFALSGSWDKTLRLWDLNQGVSTRQFISHTKDVLSVAFSADNRQIVSGSRDK 132 Query: 338 SIKIWD--LESKHIVQD 382 SIK+W+ + K+ + D Sbjct: 133 SIKLWNTLAQCKYTITD 149 Score = 37.7 bits (86), Expect = 0.022 Identities = 33/143 (23%), Positives = 66/143 (46%), Gaps = 17/143 (11%) Frame = +2 Query: 122 KLRCTLDGHGGYVSAVA--VSPDGSLCASGGKDGVTLLWDLTE---------GKRLYSLD 268 KL TL+GH G+V+ +A D + S +D L+WD+ G+ + SL Sbjct: 6 KLTGTLEGHTGWVTQIATYTRNDKTTVLSSSRDKTILVWDVDSVAPVDEGPIGRPVRSLT 65 Query: 269 AGS--IINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCT---- 430 + + + + S ++ L + ++++WDL VS++Q + T Sbjct: 66 GHNHFVSDVVISSDGQFALSGSWDKTLRLWDLNQ-----------GVSTRQFISHTKDVL 114 Query: 431 CLSWSADGSTLYAGYTDGTIRIY 499 +++SAD + +G D +I+++ Sbjct: 115 SVAFSADNRQIVSGSRDKSIKLW 137
>GBLP_NEUCR (Q01369) Guanine nucleotide-binding protein beta subunit-like| protein (Cross-pathway control WD-repeat protein cpc-2) Length = 316 Score = 206 bits (525), Expect = 3e-53 Identities = 100/168 (59%), Positives = 120/168 (71%), Gaps = 2/168 (1%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG 187 +G T WVSCVRFSPN P IVS WD+ VKVW L++CKL+ GH GY++AV +SPDG Sbjct: 145 KGHTEWVSCVRFSPNPQNPVIVSSGWDKLVKVWELSSCKLQTDHIGHTGYINAVTISPDG 204 Query: 188 SLCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESK 367 SLCASGGKDG T+LWDL E K LYSL+A I++L FSPNRYWLCAAT SI I+DLE K Sbjct: 205 SLCASGGKDGTTMLWDLNESKHLYSLNANDEIHALVFSPNRYWLCAATSSSIIIFDLEKK 264 Query: 368 HIVQDLRPEVPVSSKQML--YCTCLSWSADGSTLYAGYTDGTIRIYKI 505 V +L+PE K+ C L+WSADG TL+AGYTD IR + + Sbjct: 265 SKVDELKPEFQNIGKKSREPECVSLAWSADGQTLFAGYTDNIIRAWGV 312 Score = 52.0 bits (123), Expect = 1e-06 Identities = 35/122 (28%), Positives = 58/122 (47%), Gaps = 7/122 (5%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKL-----RCTLDGHGGYVSAVAV 175 G GWV+ + S N ++SGS D+S+ +WNLT + + L GH VS + Sbjct: 13 GHNGWVTSLATSLEN-PNMLLSGSRDKSLIIWNLTRDETSYGYPKRRLHGHSHIVSDCVI 71 Query: 176 SPDGSLCASGGKDGVTLLWDLTEG--KRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKI 349 S DG+ S D LW+L+ G R + +++ + NR + + +IK+ Sbjct: 72 SSDGAYALSASWDKTLRLWELSTGTTTRRFVGHTNDVLSVSFSADNRQIVSGSRDRTIKL 131 Query: 350 WD 355 W+ Sbjct: 132 WN 133 Score = 50.1 bits (118), Expect = 4e-06 Identities = 40/164 (24%), Positives = 70/164 (42%), Gaps = 5/164 (3%) Frame = +2 Query: 32 CVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGK 211 CV S +A +S SWD+++++W L+ GH V +V+ S D SG + Sbjct: 69 CVISSDGAYA---LSASWDKTLRLWELSTGTTTRRFVGHTNDVLSVSFSADNRQIVSGSR 125 Query: 212 DGVTLLWDLTEGKRLYSLDAGSI--INSLCFSP---NRYWLCAATQDSIKIWDLESKHIV 376 D LW+ + + G ++ + FSP N + + +K+W+L S + Sbjct: 126 DRTIKLWNTLGDCKFTITEKGHTEWVSCVRFSPNPQNPVIVSSGWDKLVKVWELSSCKLQ 185 Query: 377 QDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 D Y ++ S DGS +G DGT ++ ++ Sbjct: 186 TD-------HIGHTGYINAVTISPDGSLCASGGKDGTTMLWDLN 222 Score = 46.6 bits (109), Expect = 5e-05 Identities = 38/137 (27%), Positives = 69/137 (50%), Gaps = 8/137 (5%) Frame = +2 Query: 125 LRCTLDGHGGYVSAVAVSPDG-SLCASGGKDGVTLLWDLTEGKRLYS-----LDAGSIIN 286 L+ TL+GH G+V+++A S + ++ SG +D ++W+LT + Y L S I Sbjct: 7 LKGTLEGHNGWVTSLATSLENPNMLLSGSRDKSLIIWNLTRDETSYGYPKRRLHGHSHIV 66 Query: 287 SLCF--SPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGST 460 S C S Y L A+ ++++W+L + R V ++ + +S+SAD Sbjct: 67 SDCVISSDGAYALSASWDKTLRLWELSTG---TTTRRFVGHTNDVL----SVSFSADNRQ 119 Query: 461 LYAGYTDGTIRIYKISG 511 + +G D TI+++ G Sbjct: 120 IVSGSRDRTIKLWNTLG 136
>GBLP_TRYBR (P69104) Guanine nucleotide-binding protein beta subunit-like| protein (Activated protein kinase C receptor homolog) (Track) Length = 318 Score = 204 bits (519), Expect = 1e-52 Identities = 96/164 (58%), Positives = 120/164 (73%) Frame = +2 Query: 17 TGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLC 196 T WVSCVRFSP+ AP IVSG WD VKVW+L +L L GH YV++V VSPDGSLC Sbjct: 152 TDWVSCVRFSPSLDAPVIVSGGWDNLVKVWDLATGRLVTDLKGHTNYVTSVTVSPDGSLC 211 Query: 197 ASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIV 376 AS KDGV LWDLT+G+ L + AG+ IN +CFSPNRYW+CAAT+ I+I+DLE+K I+ Sbjct: 212 ASSDKDGVARLWDLTKGEALSEMAAGAPINQICFSPNRYWMCAATEKGIRIFDLENKDII 271 Query: 377 QDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 +L PE S K + C ++WSADGSTLY+GYTD IR++ +S Sbjct: 272 VELAPEHQGSKKIVPECVSIAWSADGSTLYSGYTDNVIRVWGVS 315 Score = 76.3 bits (186), Expect = 6e-14 Identities = 54/173 (31%), Positives = 90/173 (52%), Gaps = 7/173 (4%) Frame = +2 Query: 11 GPTGWVSCVRFSPN-NFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG 187 G + +VS V S N NFA VS SWD S+++WNL N + + GH V +VA SPD Sbjct: 65 GHSAFVSDVALSNNGNFA---VSASWDHSLRLWNLQNGQCQYKFLGHTKDVLSVAFSPDN 121 Query: 188 SLCASGGKDGVTLLWDLTEGKRLYSLDAGS---IINSLCFSPN---RYWLCAATQDSIKI 349 SGG+D +W++ +G+ +++L G+ ++ + FSP+ + + +K+ Sbjct: 122 RQIVSGGRDNALRVWNV-KGECMHTLSRGAHTDWVSCVRFSPSLDAPVIVSGGWDNLVKV 180 Query: 350 WDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 WDL + +V DL+ Y T ++ S DGS + DG R++ ++ Sbjct: 181 WDLATGRLVTDLKGHTN-------YVTSVTVSPDGSLCASSDKDGVARLWDLT 226 Score = 50.1 bits (118), Expect = 4e-06 Identities = 43/178 (24%), Positives = 80/178 (44%), Gaps = 12/178 (6%) Frame = +2 Query: 11 GPTGWVSCVRFSPN-NFAPTIVSGSWDRSVKVW--NLTNCKLRCT-------LDGHGGYV 160 G GWV+ + A +VS S D+++ W N C+ L+GH +V Sbjct: 11 GHRGWVTSLACPQTPETATKVVSTSRDKTLLSWGPNPDRHSSECSYGLPDRRLEGHSAFV 70 Query: 161 SAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYS-LDAGSIINSLCFSP-NRYWLCAATQ 334 S VA+S +G+ S D LW+L G+ Y L + S+ FSP NR + Sbjct: 71 SDVALSNNGNFAVSASWDHSLRLWNLQNGQCQYKFLGHTKDVLSVAFSPDNRQIVSGGRD 130 Query: 335 DSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 +++++W+++ + + R + + C S S D + +G D ++++ ++ Sbjct: 131 NALRVWNVKGECMHTLSRG----AHTDWVSCVRFSPSLDAPVIVSGGWDNLVKVWDLA 184
>GBLP_TRYBB (P69103) Guanine nucleotide-binding protein beta subunit-like| protein (Activated protein kinase C receptor homolog) Length = 318 Score = 204 bits (519), Expect = 1e-52 Identities = 96/164 (58%), Positives = 120/164 (73%) Frame = +2 Query: 17 TGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLC 196 T WVSCVRFSP+ AP IVSG WD VKVW+L +L L GH YV++V VSPDGSLC Sbjct: 152 TDWVSCVRFSPSLDAPVIVSGGWDNLVKVWDLATGRLVTDLKGHTNYVTSVTVSPDGSLC 211 Query: 197 ASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIV 376 AS KDGV LWDLT+G+ L + AG+ IN +CFSPNRYW+CAAT+ I+I+DLE+K I+ Sbjct: 212 ASSDKDGVARLWDLTKGEALSEMAAGAPINQICFSPNRYWMCAATEKGIRIFDLENKDII 271 Query: 377 QDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 +L PE S K + C ++WSADGSTLY+GYTD IR++ +S Sbjct: 272 VELAPEHQGSKKIVPECVSIAWSADGSTLYSGYTDNVIRVWGVS 315 Score = 76.3 bits (186), Expect = 6e-14 Identities = 54/173 (31%), Positives = 90/173 (52%), Gaps = 7/173 (4%) Frame = +2 Query: 11 GPTGWVSCVRFSPN-NFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG 187 G + +VS V S N NFA VS SWD S+++WNL N + + GH V +VA SPD Sbjct: 65 GHSAFVSDVALSNNGNFA---VSASWDHSLRLWNLQNGQCQYKFLGHTKDVLSVAFSPDN 121 Query: 188 SLCASGGKDGVTLLWDLTEGKRLYSLDAGS---IINSLCFSPN---RYWLCAATQDSIKI 349 SGG+D +W++ +G+ +++L G+ ++ + FSP+ + + +K+ Sbjct: 122 RQIVSGGRDNALRVWNV-KGECMHTLSRGAHTDWVSCVRFSPSLDAPVIVSGGWDNLVKV 180 Query: 350 WDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 WDL + +V DL+ Y T ++ S DGS + DG R++ ++ Sbjct: 181 WDLATGRLVTDLKGHTN-------YVTSVTVSPDGSLCASSDKDGVARLWDLT 226 Score = 50.1 bits (118), Expect = 4e-06 Identities = 43/178 (24%), Positives = 80/178 (44%), Gaps = 12/178 (6%) Frame = +2 Query: 11 GPTGWVSCVRFSPN-NFAPTIVSGSWDRSVKVW--NLTNCKLRCT-------LDGHGGYV 160 G GWV+ + A +VS S D+++ W N C+ L+GH +V Sbjct: 11 GHRGWVTSLACPQTPETATKVVSTSRDKTLLSWGPNPDRHSSECSYGLPDRRLEGHSAFV 70 Query: 161 SAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYS-LDAGSIINSLCFSP-NRYWLCAATQ 334 S VA+S +G+ S D LW+L G+ Y L + S+ FSP NR + Sbjct: 71 SDVALSNNGNFAVSASWDHSLRLWNLQNGQCQYKFLGHTKDVLSVAFSPDNRQIVSGGRD 130 Query: 335 DSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 +++++W+++ + + R + + C S S D + +G D ++++ ++ Sbjct: 131 NALRVWNVKGECMHTLSRG----AHTDWVSCVRFSPSLDAPVIVSGGWDNLVKVWDLA 184
>GBLP_DICDI (P46800) Guanine nucleotide-binding protein beta subunit-like| protein Length = 329 Score = 194 bits (492), Expect = 2e-49 Identities = 95/172 (55%), Positives = 116/172 (67%), Gaps = 10/172 (5%) Frame = +2 Query: 23 WVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCAS 202 WVSC+RFSPN PTIVSGSWD VK+W++ + K TL H GYV+ V +SPDGSLCAS Sbjct: 158 WVSCIRFSPNT--PTIVSGSWDNKVKIWDIKSFKCNHTLTDHTGYVNTVTISPDGSLCAS 215 Query: 203 GGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQD 382 GGKD LW+L+ GK LY L+A + IN+L FSPN+YWL AAT D I IWDL +K ++ + Sbjct: 216 GGKDTFACLWELSSGKPLYKLEARNTINALAFSPNKYWLSAATDDKIIIWDLLTKQVLAE 275 Query: 383 LRPEV----------PVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 + PEV S + C L+WSADGS LYAGY DG IR+YK S Sbjct: 276 IVPEVKEQAFDSKKKKESKPKAPACLSLAWSADGSVLYAGYNDGLIRVYKSS 327 Score = 75.5 bits (184), Expect = 1e-13 Identities = 53/178 (29%), Positives = 85/178 (47%), Gaps = 10/178 (5%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNC------KLRCTLDGHGGYVSAVA 172 G G+V+ + SP N TI+S S D++V VW LT K +L GH +V V Sbjct: 19 GHNGFVTSIAVSPEN-PDTIISSSRDKTVMVWQLTPTDATSPGKAHRSLKGHSHFVQDVV 77 Query: 173 VSPDGSLCASGGKDGVTLLWDLTEG--KRLYSLDAGSIINSLCFSPNRYWLCAATQDSIK 346 +S DG SG D LWD+T+G RL+ +++ S NR + + +IK Sbjct: 78 ISHDGQFALSGSWDNTLRLWDITKGVSTRLFKGHTQDVMSVAFSSDNRQIISGSRDATIK 137 Query: 347 IWDL--ESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISGF 514 +W+ E K ++ PE + +C+ +S + T+ +G D ++I+ I F Sbjct: 138 VWNTLGECKFTLEG--PEA-----HQDWVSCIRFSPNTPTIVSGSWDNKVKIWDIKSF 188 Score = 55.5 bits (132), Expect = 1e-07 Identities = 41/154 (26%), Positives = 74/154 (48%), Gaps = 8/154 (5%) Frame = +2 Query: 71 VSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGK 250 +SGSWD ++++W++T GH V +VA S D SG +D +W+ T G+ Sbjct: 86 LSGSWDNTLRLWDITKGVSTRLFKGHTQDVMSVAFSSDNRQIISGSRDATIKVWN-TLGE 144 Query: 251 RLYSLDAGSI----INSLCFSPNRYWLCAATQDS-IKIWDLES---KHIVQDLRPEVPVS 406 ++L+ ++ + FSPN + + + D+ +KIWD++S H + D Sbjct: 145 CKFTLEGPEAHQDWVSCIRFSPNTPTIVSGSWDNKVKIWDIKSFKCNHTLTD-------- 196 Query: 407 SKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 Y ++ S DGS +G D ++++S Sbjct: 197 --HTGYVNTVTISPDGSLCASGGKDTFACLWELS 228
>GBLP_SCHPO (Q10281) Guanine nucleotide-binding protein beta subunit-like| protein (Receptor of activated protein kinase C) Length = 314 Score = 187 bits (476), Expect = 1e-47 Identities = 93/168 (55%), Positives = 119/168 (70%), Gaps = 2/168 (1%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G + WVSCVRFSPN T VS WD++VKVW+L LR + GH GYVSAV +SPDGS Sbjct: 146 GHSDWVSCVRFSPNPDNLTFVSAGWDKAVKVWDLETFSLRTSHYGHTGYVSAVTISPDGS 205 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKH 370 LCASGG+DG +LWDL E LYSL+A + IN+L FSPNRYWLCAAT SI+I+DLE++ Sbjct: 206 LCASGGRDGTLMLWDLNESTHLYSLEAKANINALVFSPNRYWLCAATGSSIRIFDLETQE 265 Query: 371 IVQDLRPE-VPVSSKQM-LYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 V +L + V V K C L+WS DG TL++G+TD IR+++++ Sbjct: 266 KVDELTVDFVGVGKKSSEPECISLTWSPDGQTLFSGWTDNLIRVWQVT 313 Score = 62.0 bits (149), Expect = 1e-09 Identities = 38/151 (25%), Positives = 73/151 (48%), Gaps = 5/151 (3%) Frame = +2 Query: 71 VSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGK 250 +S SWD+++++W+L + GH V +V++SPD SG +D +W++ Sbjct: 79 LSASWDKTIRLWDLEKGECTHQFVGHTSDVLSVSISPDNRQVVSGSRDKTIKIWNIIGNC 138 Query: 251 RLYSLDAG--SIINSLCFSP---NRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQ 415 + D G ++ + FSP N ++ A ++K+WDLE+ + Sbjct: 139 KYTITDGGHSDWVSCVRFSPNPDNLTFVSAGWDKAVKVWDLETFSLRTSHYGHTG----- 193 Query: 416 MLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 Y + ++ S DGS +G DGT+ ++ ++ Sbjct: 194 --YVSAVTISPDGSLCASGGRDGTLMLWDLN 222 Score = 60.1 bits (144), Expect = 4e-09 Identities = 48/178 (26%), Positives = 81/178 (45%), Gaps = 9/178 (5%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRC-----TLDGHGGYVSAVAV 175 G +GWV+ + +P N ++SGS D+S+ +WNL + L GH +VS A+ Sbjct: 13 GHSGWVTSLSTAPEN-PDILLSGSRDKSIILWNLVRDDVNYGVAQRRLTGHSHFVSDCAL 71 Query: 176 SPDGSLCASGGKDGVTLLWDLTEGKRLYS-LDAGSIINSLCFSP-NRYWLCAATQDSIKI 349 S D S D LWDL +G+ + + S + S+ SP NR + + +IKI Sbjct: 72 SFDSHYALSASWDKTIRLWDLEKGECTHQFVGHTSDVLSVSISPDNRQVVSGSRDKTIKI 131 Query: 350 WDL--ESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISGFS 517 W++ K+ + D + C S + D T + D ++++ + FS Sbjct: 132 WNIIGNCKYTITD------GGHSDWVSCVRFSPNPDNLTFVSAGWDKAVKVWDLETFS 183 Score = 48.5 bits (114), Expect = 1e-05 Identities = 37/137 (27%), Positives = 63/137 (45%), Gaps = 8/137 (5%) Frame = +2 Query: 125 LRCTLDGHGGYVSAVAVSPDG-SLCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCF- 298 LR TL+GH G+V++++ +P+ + SG +D +LW+L Y + + F Sbjct: 7 LRATLEGHSGWVTSLSTAPENPDILLSGSRDKSIILWNLVRDDVNYGVAQRRLTGHSHFV 66 Query: 299 ------SPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGST 460 + Y L A+ +I++WDLE V +S + +S S D Sbjct: 67 SDCALSFDSHYALSASWDKTIRLWDLEKGECTHQF---VGHTSDVL----SVSISPDNRQ 119 Query: 461 LYAGYTDGTIRIYKISG 511 + +G D TI+I+ I G Sbjct: 120 VVSGSRDKTIKIWNIIG 136
>GBLP_LEIIN (P62884) Guanine nucleotide-binding protein beta subunit-like| protein (Antigen LACK) (LiP36) (p36Li) Length = 312 Score = 186 bits (473), Expect = 3e-47 Identities = 85/166 (51%), Positives = 116/166 (69%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G WVS + FSP+ P +VSGSWD ++KVWN+ K TL GH YVS V VSPDGS Sbjct: 148 GHEDWVSSICFSPSLEHPIVVSGSWDNTIKVWNVNGGKCERTLKGHSNYVSTVTVSPDGS 207 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKH 370 LCASGGKDG LLWDL+ G++L+ ++ S IN + FSPNR+W+C AT+ S+ ++DLESK Sbjct: 208 LCASGGKDGAALLWDLSTGEQLFKINVESPINQIAFSPNRFWMCVATERSLSVYDLESKA 267 Query: 371 IVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 ++ +L P+ S+ C ++WSADG+TLY+G+ D IR++ IS Sbjct: 268 VIAELTPDGAKPSE----CISIAWSADGNTLYSGHKDNLIRVWSIS 309 Score = 68.6 bits (166), Expect = 1e-11 Identities = 49/171 (28%), Positives = 84/171 (49%), Gaps = 5/171 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G TG+VSCV + + ++ SWDRS+++W+L N + + H V AVA SPD Sbjct: 63 GHTGFVSCVSLA--HATDYALTASWDRSIRMWDLRNGQCQRKFLKHTKDVLAVAFSPDDR 120 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAG--SIINSLCFSP---NRYWLCAATQDSIKIWD 355 L S G+D V +W++ L G ++S+CFSP + + + ++IK+W+ Sbjct: 121 LIVSAGRDNVIRVWNVAGECMHEFLRDGHEDWVSSICFSPSLEHPIVVSGSWDNTIKVWN 180 Query: 356 LESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 + + L+ Y + ++ S DGS +G DG ++ +S Sbjct: 181 VNGGKCERTLK-------GHSNYVSTVTVSPDGSLCASGGKDGAALLWDLS 224 Score = 44.3 bits (103), Expect = 2e-04 Identities = 30/127 (23%), Positives = 64/127 (50%), Gaps = 2/127 (1%) Frame = +2 Query: 137 LDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGK-RLYSLDAGSIINSLCFSPNRY 313 L+GH G+VS V+++ + D +WDL G+ + L + ++ FSP+ Sbjct: 61 LEGHTGFVSCVSLAHATDYALTASWDRSIRMWDLRNGQCQRKFLKHTKDVLAVAFSPDDR 120 Query: 314 WLCAATQDS-IKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTI 490 + +A +D+ I++W++ + + + LR + + C S S + + +G D TI Sbjct: 121 LIVSAGRDNVIRVWNVAGECMHEFLRD----GHEDWVSSICFSPSLEHPIVVSGSWDNTI 176 Query: 491 RIYKISG 511 +++ ++G Sbjct: 177 KVWNVNG 183 Score = 33.9 bits (76), Expect = 0.32 Identities = 21/78 (26%), Positives = 41/78 (52%), Gaps = 3/78 (3%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVS---AVAVSPDGSLC 196 ++ + FSPN F + + +RS+ V++L + + L G S ++A S DG+ Sbjct: 238 INQIAFSPNRFWMCVAT---ERSLSVYDLESKAVIAELTPDGAKPSECISIAWSADGNTL 294 Query: 197 ASGGKDGVTLLWDLTEGK 250 SG KD + +W +++ + Sbjct: 295 YSGHKDNLIRVWSISDAE 312
>GBLP_LEICH (P62883) Guanine nucleotide-binding protein beta subunit-like| protein (Antigen LACK) Length = 312 Score = 186 bits (473), Expect = 3e-47 Identities = 85/166 (51%), Positives = 116/166 (69%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G WVS + FSP+ P +VSGSWD ++KVWN+ K TL GH YVS V VSPDGS Sbjct: 148 GHEDWVSSICFSPSLEHPIVVSGSWDNTIKVWNVNGGKCERTLKGHSNYVSTVTVSPDGS 207 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKH 370 LCASGGKDG LLWDL+ G++L+ ++ S IN + FSPNR+W+C AT+ S+ ++DLESK Sbjct: 208 LCASGGKDGAALLWDLSTGEQLFKINVESPINQIAFSPNRFWMCVATERSLSVYDLESKA 267 Query: 371 IVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 ++ +L P+ S+ C ++WSADG+TLY+G+ D IR++ IS Sbjct: 268 VIAELTPDGAKPSE----CISIAWSADGNTLYSGHKDNLIRVWSIS 309 Score = 68.6 bits (166), Expect = 1e-11 Identities = 49/171 (28%), Positives = 84/171 (49%), Gaps = 5/171 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G TG+VSCV + + ++ SWDRS+++W+L N + + H V AVA SPD Sbjct: 63 GHTGFVSCVSLA--HATDYALTASWDRSIRMWDLRNGQCQRKFLKHTKDVLAVAFSPDDR 120 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAG--SIINSLCFSP---NRYWLCAATQDSIKIWD 355 L S G+D V +W++ L G ++S+CFSP + + + ++IK+W+ Sbjct: 121 LIVSAGRDNVIRVWNVAGECMHEFLRDGHEDWVSSICFSPSLEHPIVVSGSWDNTIKVWN 180 Query: 356 LESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 + + L+ Y + ++ S DGS +G DG ++ +S Sbjct: 181 VNGGKCERTLK-------GHSNYVSTVTVSPDGSLCASGGKDGAALLWDLS 224 Score = 44.3 bits (103), Expect = 2e-04 Identities = 30/127 (23%), Positives = 64/127 (50%), Gaps = 2/127 (1%) Frame = +2 Query: 137 LDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGK-RLYSLDAGSIINSLCFSPNRY 313 L+GH G+VS V+++ + D +WDL G+ + L + ++ FSP+ Sbjct: 61 LEGHTGFVSCVSLAHATDYALTASWDRSIRMWDLRNGQCQRKFLKHTKDVLAVAFSPDDR 120 Query: 314 WLCAATQDS-IKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTI 490 + +A +D+ I++W++ + + + LR + + C S S + + +G D TI Sbjct: 121 LIVSAGRDNVIRVWNVAGECMHEFLRD----GHEDWVSSICFSPSLEHPIVVSGSWDNTI 176 Query: 491 RIYKISG 511 +++ ++G Sbjct: 177 KVWNVNG 183 Score = 33.9 bits (76), Expect = 0.32 Identities = 21/78 (26%), Positives = 41/78 (52%), Gaps = 3/78 (3%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVS---AVAVSPDGSLC 196 ++ + FSPN F + + +RS+ V++L + + L G S ++A S DG+ Sbjct: 238 INQIAFSPNRFWMCVAT---ERSLSVYDLESKAVIAELTPDGAKPSECISIAWSADGNTL 294 Query: 197 ASGGKDGVTLLWDLTEGK 250 SG KD + +W +++ + Sbjct: 295 YSGHKDNLIRVWSISDAE 312
>GBLP_LEIMA (Q25306) Guanine nucleotide-binding protein beta subunit-like| protein (Antigen LACK) Length = 312 Score = 185 bits (470), Expect = 7e-47 Identities = 85/166 (51%), Positives = 116/166 (69%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G WVS + FSP+ P +VSGSWD ++KVWN+ K TL GH YVS V VSPDGS Sbjct: 148 GHEDWVSSICFSPSLEHPIVVSGSWDNTIKVWNVNGGKCERTLKGHSNYVSTVTVSPDGS 207 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKH 370 LCASGGKDG LLWDL+ G++L+ ++ S IN + FSPNR+W+C AT+ S+ ++DLESK Sbjct: 208 LCASGGKDGAALLWDLSTGEQLFKINVESPINQIGFSPNRFWMCVATERSLSVYDLESKA 267 Query: 371 IVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 ++ +L P+ S+ C ++WSADG+TLY+G+ D IR++ IS Sbjct: 268 VIAELTPDGAKPSE----CISIAWSADGNTLYSGHKDNLIRVWSIS 309 Score = 68.6 bits (166), Expect = 1e-11 Identities = 49/171 (28%), Positives = 84/171 (49%), Gaps = 5/171 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G TG+VSCV + + ++ SWDRS+++W+L N + + H V AVA SPD Sbjct: 63 GHTGFVSCVSLA--HATDYALTASWDRSIRMWDLRNGQCQRKFLKHTKDVLAVAFSPDDR 120 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAG--SIINSLCFSP---NRYWLCAATQDSIKIWD 355 L S G+D V +W++ L G ++S+CFSP + + + ++IK+W+ Sbjct: 121 LIVSAGRDNVIRVWNVAGECMHEFLRDGHEDWVSSICFSPSLEHPIVVSGSWDNTIKVWN 180 Query: 356 LESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 + + L+ Y + ++ S DGS +G DG ++ +S Sbjct: 181 VNGGKCERTLK-------GHSNYVSTVTVSPDGSLCASGGKDGAALLWDLS 224 Score = 44.3 bits (103), Expect = 2e-04 Identities = 30/127 (23%), Positives = 64/127 (50%), Gaps = 2/127 (1%) Frame = +2 Query: 137 LDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGK-RLYSLDAGSIINSLCFSPNRY 313 L+GH G+VS V+++ + D +WDL G+ + L + ++ FSP+ Sbjct: 61 LEGHTGFVSCVSLAHATDYALTASWDRSIRMWDLRNGQCQRKFLKHTKDVLAVAFSPDDR 120 Query: 314 WLCAATQDS-IKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTI 490 + +A +D+ I++W++ + + + LR + + C S S + + +G D TI Sbjct: 121 LIVSAGRDNVIRVWNVAGECMHEFLRD----GHEDWVSSICFSPSLEHPIVVSGSWDNTI 176 Query: 491 RIYKISG 511 +++ ++G Sbjct: 177 KVWNVNG 183 Score = 33.5 bits (75), Expect = 0.42 Identities = 21/78 (26%), Positives = 41/78 (52%), Gaps = 3/78 (3%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVS---AVAVSPDGSLC 196 ++ + FSPN F + + +RS+ V++L + + L G S ++A S DG+ Sbjct: 238 INQIGFSPNRFWMCVAT---ERSLSVYDLESKAVIAELTPDGAKPSECISIAWSADGNTL 294 Query: 197 ASGGKDGVTLLWDLTEGK 250 SG KD + +W +++ + Sbjct: 295 YSGHKDNLIRVWSISDAE 312
>GBLP_YEAST (P38011) Guanine nucleotide-binding protein beta subunit-like| protein (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 318 Score = 150 bits (380), Expect = 2e-36 Identities = 77/170 (45%), Positives = 103/170 (60%), Gaps = 5/170 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAP----TIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVS 178 G WVS VR PN A TI+S D+ VK WNL ++ GH ++ + S Sbjct: 145 GHNDWVSQVRVVPNEKADDDSVTIISAGNDKMVKAWNLNQFQIEADFIGHNSNINTLTAS 204 Query: 179 PDGSLCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDL 358 PDG+L AS GKDG +LW+L K +Y+L A + SL FSPNRYWL AAT IK++ L Sbjct: 205 PDGTLIASAGKDGEIMLWNLAAKKAMYTLSAQDEVFSLAFSPNRYWLAAATATGIKVFSL 264 Query: 359 ESKHIVQDLRPEVPVSSKQM-LYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 + +++V DLRPE SK + L+WSADG TL+AGYTD IR++++ Sbjct: 265 DPQYLVDDLRPEFAGYSKAAEPHAVSLAWSADGQTLFAGYTDNVIRVWQV 314 Score = 40.0 bits (92), Expect = 0.004 Identities = 33/137 (24%), Positives = 61/137 (44%), Gaps = 8/137 (5%) Frame = +2 Query: 125 LRCTLDGHGGYVSAVAVSP-DGSLCASGGKDGVTLLWDLTEGKRLYSLDAGS-------I 280 LR TL+GH G+V+++A S +L S +D + W LT + + + S + Sbjct: 8 LRGTLEGHNGWVTSLATSAGQPNLLLSASRDKTLISWKLTGDDQKFGVPVRSFKGHSHIV 67 Query: 281 INSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGST 460 + + Y L A+ ++++WD+ + Q V K + + A S Sbjct: 68 QDCTLTADGAYALSASWDKTLRLWDVATGETYQRF-----VGHKSDVMSVDIDKKA--SM 120 Query: 461 LYAGYTDGTIRIYKISG 511 + +G D TI+++ I G Sbjct: 121 IISGSRDKTIKVWTIKG 137 Score = 35.8 bits (81), Expect = 0.085 Identities = 30/127 (23%), Positives = 55/127 (43%), Gaps = 8/127 (6%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRC-----TLDGHGGYVSAVAV 175 G GWV+ + S ++S S D+++ W LT + + GH V + Sbjct: 14 GHNGWVTSLATSAGQ-PNLLLSASRDKTLISWKLTGDDQKFGVPVRSFKGHSHIVQDCTL 72 Query: 176 SPDGSLCASGGKDGVTLLWDLTEGKRLYSLDAG--SIINSLCFSPNRYWLCAATQD-SIK 346 + DG+ S D LWD+ G+ Y G S + S+ + + ++D +IK Sbjct: 73 TADGAYALSASWDKTLRLWDVATGE-TYQRFVGHKSDVMSVDIDKKASMIISGSRDKTIK 131 Query: 347 IWDLESK 367 +W ++ + Sbjct: 132 VWTIKGQ 138
>YY46_ANASP (Q8YRI1) Hypothetical WD-repeat protein alr3466| Length = 1526 Score = 101 bits (251), Expect = 2e-21 Identities = 52/169 (30%), Positives = 97/169 (57%), Gaps = 2/169 (1%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG 187 +G T WV+ V F+P+ T+ SGS D++V++W + + K CT GH +V++V +PDG Sbjct: 1197 QGHTSWVNSVVFNPDG--STLASGSSDQTVRLWEINSSKCLCTFQGHTSWVNSVVFNPDG 1254 Query: 188 SLCASGGKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQD-SIKIWDLE 361 S+ ASG D LWD++ K L++ + +NS+ F+P+ L + + D ++++W++ Sbjct: 1255 SMLASGSSDKTVRLWDISSSKCLHTFQGHTNWVNSVAFNPDGSMLASGSGDQTVRLWEIS 1314 Query: 362 SKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 S + + + + +++S DG+ L +G D T+R++ IS Sbjct: 1315 SSKCLHTFQGHTS-------WVSSVTFSPDGTMLASGSDDQTVRLWSIS 1356 Score = 98.6 bits (244), Expect = 1e-20 Identities = 57/169 (33%), Positives = 96/169 (56%), Gaps = 2/169 (1%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG 187 +G T WV + FSPN T+ +GS D+ V++W++++ K TL GH +V+AVA SPDG Sbjct: 1113 QGYTSWVRFLVFSPNGV--TLANGSSDQIVRLWDISSKKCLYTLQGHTNWVNAVAFSPDG 1170 Query: 188 SLCASGGKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQD-SIKIWDLE 361 + ASG D LWD++ K LY L S +NS+ F+P+ L + + D ++++W++ Sbjct: 1171 ATLASGSGDQTVRLWDISSSKCLYILQGHTSWVNSVVFNPDGSTLASGSSDQTVRLWEIN 1230 Query: 362 SKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 S + + + + ++ DGS L +G +D T+R++ IS Sbjct: 1231 SSKCLCTFQGHTS-------WVNSVVFNPDGSMLASGSSDKTVRLWDIS 1272 Score = 97.1 bits (240), Expect = 3e-20 Identities = 60/168 (35%), Positives = 93/168 (55%), Gaps = 5/168 (2%) Frame = +2 Query: 20 GWVSCVR---FSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G SCVR FS + + SGS D++V++W++++ TL GH V +V SPDG+ Sbjct: 1030 GHTSCVRSVVFSSDG--AMLASGSDDQTVRLWDISSGNCLYTLQGHTSCVRSVVFSPDGA 1087 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQDSI-KIWDLES 364 + ASGG D + LWD++ G LY+L S + L FSPN L + D I ++WD+ S Sbjct: 1088 MLASGGDDQIVRLWDISSGNCLYTLQGYTSWVRFLVFSPNGVTLANGSSDQIVRLWDISS 1147 Query: 365 KHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 K + L+ + +++S DG+TL +G D T+R++ IS Sbjct: 1148 KKCLYTLQGHTN-------WVNAVAFSPDGATLASGSGDQTVRLWDIS 1188 Score = 91.3 bits (225), Expect = 2e-18 Identities = 53/169 (31%), Positives = 94/169 (55%), Gaps = 2/169 (1%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG 187 +G T WV+ V F+P+ + SGS D++V++W +++ K T GH +VS+V SPDG Sbjct: 1281 QGHTNWVNSVAFNPDG--SMLASGSGDQTVRLWEISSSKCLHTFQGHTSWVSSVTFSPDG 1338 Query: 188 SLCASGGKDGVTLLWDLTEGKRLYS-LDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLE 361 ++ ASG D LW ++ G+ LY+ L + + S+ FSP+ L + + D ++++W + Sbjct: 1339 TMLASGSDDQTVRLWSISSGECLYTFLGHTNWVGSVIFSPDGAILASGSGDQTVRLWSIS 1398 Query: 362 SKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 S + L+ + + +S DG+ L +G D T+R++ IS Sbjct: 1399 SGKCLYTLQ-------GHNNWVGSIVFSPDGTLLASGSDDQTVRLWNIS 1440 Score = 89.4 bits (220), Expect = 6e-18 Identities = 46/130 (35%), Positives = 79/130 (60%), Gaps = 2/130 (1%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G T WV V FSP+ + SGS D++V++W++++ K TL GH +V ++ SPDG+ Sbjct: 1366 GHTNWVGSVIFSPDG--AILASGSGDQTVRLWSISSGKCLYTLQGHNNWVGSIVFSPDGT 1423 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAG-SIINSLCFSPNRYWLCAATQD-SIKIWDLES 364 L ASG D LW+++ G+ LY+L + + S+ FS + L + + D +IK+WD+++ Sbjct: 1424 LLASGSDDQTVRLWNISSGECLYTLHGHINSVRSVAFSSDGLILASGSDDETIKLWDVKT 1483 Query: 365 KHIVQDLRPE 394 ++ L+ E Sbjct: 1484 GECIKTLKSE 1493 Score = 73.2 bits (178), Expect = 5e-13 Identities = 46/171 (26%), Positives = 86/171 (50%), Gaps = 2/171 (1%) Frame = +2 Query: 2 SARGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSP 181 + +G WV+ V FS + + SGS D++V++W++++ + T GH V +V SP Sbjct: 901 TCKGHNSWVNSVGFSQDG--KMLASGSDDQTVRLWDISSGQCLKTFKGHTSRVRSVVFSP 958 Query: 182 DGSLCASGGKDGVTLLWDLTEGKRLYSLDAGS-IINSLCFSPNRYWLCAATQD-SIKIWD 355 + + ASG D LWD++ G+ LY + + S+ F+ + L + D ++++WD Sbjct: 959 NSLMLASGSSDQTVRLWDISSGECLYIFQGHTGWVYSVAFNLDGSMLATGSGDQTVRLWD 1018 Query: 356 LESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 + S + + +S+DG+ L +G D T+R++ IS Sbjct: 1019 ISSSQCFY-------IFQGHTSCVRSVVFSSDGAMLASGSDDQTVRLWDIS 1062 Score = 72.0 bits (175), Expect = 1e-12 Identities = 48/165 (29%), Positives = 78/165 (47%), Gaps = 2/165 (1%) Frame = +2 Query: 20 GWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCA 199 G V V FSP+ +G V+ W K T GH +V++V S DG + A Sbjct: 865 GSVLTVAFSPDG--KLFATGDSGGIVRFWEAATGKELLTCKGHNSWVNSVGFSQDGKMLA 922 Query: 200 SGGKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQD-SIKIWDLESKHI 373 SG D LWD++ G+ L + S + S+ FSPN L + + D ++++WD+ S Sbjct: 923 SGSDDQTVRLWDISSGQCLKTFKGHTSRVRSVVFSPNSLMLASGSSDQTVRLWDISSGEC 982 Query: 374 VQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 + + + ++++ DGS L G D T+R++ IS Sbjct: 983 LY-------IFQGHTGWVYSVAFNLDGSMLATGSGDQTVRLWDIS 1020 Score = 62.4 bits (150), Expect = 8e-10 Identities = 33/95 (34%), Positives = 53/95 (55%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG 187 +G WV + FSP+ + SGS D++V++WN+++ + TL GH V +VA S DG Sbjct: 1407 QGHNNWVGSIVFSPDG--TLLASGSDDQTVRLWNISSGECLYTLHGHINSVRSVAFSSDG 1464 Query: 188 SLCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSL 292 + ASG D LWD+ G+ + +L + I + Sbjct: 1465 LILASGSDDETIKLWDVKTGECIKTLKSEKIYEGM 1499
>PKWA_THECU (P49695) Probable serine/threonine-protein kinase pkwA (EC 2.7.11.1)| Length = 742 Score = 91.3 bits (225), Expect = 2e-18 Identities = 55/167 (32%), Positives = 84/167 (50%), Gaps = 1/167 (0%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G T +V + FSP+ + SGS D + ++WN+ L GH YV AVA SPDGS Sbjct: 541 GHTHYVLDIAFSPDG--SMVASGSRDGTARLWNVATGTEHAVLKGHTDYVYAVAFSPDGS 598 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQDSIKIWDLESK 367 + ASG +DG LWD+ GK L A + SL FSP+ L + ++ +WD+ S Sbjct: 599 MVASGSRDGTIRLWDVATGKERDVLQAPAENVVSLAFSPDGSMLVHGSDSTVHLWDVASG 658 Query: 368 HIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 + + +++S DG+ L +G D TIR++ ++ Sbjct: 659 EALHTFEGHTD-------WVRAVAFSPDGALLASGSDDRTIRLWDVA 698 Score = 82.8 bits (203), Expect = 6e-16 Identities = 52/168 (30%), Positives = 88/168 (52%), Gaps = 2/168 (1%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G T WV V FSP+ + SGS D +V++W++ + R +GH YV +A SPDGS Sbjct: 499 GHTDWVRAVAFSPDG--ALLASGSDDATVRLWDVAAAEERAVFEGHTHYVLDIAFSPDGS 556 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGS-IINSLCFSPNRYWLCAATQD-SIKIWDLES 364 + ASG +DG LW++ G L + + ++ FSP+ + + ++D +I++WD+ + Sbjct: 557 MVASGSRDGTARLWNVATGTEHAVLKGHTDYVYAVAFSPDGSMVASGSRDGTIRLWDVAT 616 Query: 365 KHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 E V L++S DGS L G +D T+ ++ ++ Sbjct: 617 -------GKERDVLQAPAENVVSLAFSPDGSMLVHG-SDSTVHLWDVA 656 Score = 75.1 bits (183), Expect = 1e-13 Identities = 52/167 (31%), Positives = 83/167 (49%), Gaps = 9/167 (5%) Frame = +2 Query: 35 VRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKD 214 V FSP + GS D+ + VW++ + TL+GH +V AVA SPDG+L ASG D Sbjct: 465 VAFSPGG--SLLAGGSGDKLIHVWDVASGDELHTLEGHTDWVRAVAFSPDGALLASGSDD 522 Query: 215 GVTLLWDLT--------EGKRLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLESK 367 LWD+ EG Y LD + FSP+ + + ++D + ++W++ + Sbjct: 523 ATVRLWDVAAAEERAVFEGHTHYVLD-------IAFSPDGSMVASGSRDGTARLWNVAT- 574 Query: 368 HIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 E V Y +++S DGS + +G DGTIR++ ++ Sbjct: 575 ------GTEHAVLKGHTDYVYAVAFSPDGSMVASGSRDGTIRLWDVA 615 Score = 58.9 bits (141), Expect = 9e-09 Identities = 35/117 (29%), Positives = 63/117 (53%), Gaps = 2/117 (1%) Frame = +2 Query: 164 AVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLDAGS-IINSLCFSPNRYWLCAATQD- 337 AVA SP GSL A G D + +WD+ G L++L+ + + ++ FSP+ L + + D Sbjct: 464 AVAFSPGGSLLAGGSGDKLIHVWDVASGDELHTLEGHTDWVRAVAFSPDGALLASGSDDA 523 Query: 338 SIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 ++++WD+ + E V Y +++S DGS + +G DGT R++ ++ Sbjct: 524 TVRLWDVAAAE-------ERAVFEGHTHYVLDIAFSPDGSMVASGSRDGTARLWNVA 573 Score = 57.4 bits (137), Expect = 3e-08 Identities = 28/76 (36%), Positives = 44/76 (57%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G T WV V FSP+ + SGS DR++++W++ + TL+GH V +VA P+G+ Sbjct: 666 GHTDWVRAVAFSPDG--ALLASGSDDRTIRLWDVAAQEEHTTLEGHTEPVHSVAFHPEGT 723 Query: 191 LCASGGKDGVTLLWDL 238 AS +DG +W + Sbjct: 724 TLASASEDGTIRIWPI 739
>HETE1_PODAN (Q00808) Vegetatible incompatibility protein HET-E-1| Length = 1356 Score = 88.2 bits (217), Expect = 1e-17 Identities = 54/157 (34%), Positives = 83/157 (52%), Gaps = 2/157 (1%) Frame = +2 Query: 35 VRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKD 214 V FSP+ + SGS D ++K+W+ + TL+GHGG+V +VA SPDG ASG D Sbjct: 1099 VAFSPDG--QRVASGSIDGTIKIWDAASGTCTQTLEGHGGWVHSVAFSPDGQRVASGSID 1156 Query: 215 GVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQDLR 388 G +WD G +L+ G + S+ FSP+ + + + D +IKIWD S Q L Sbjct: 1157 GTIKIWDAASGTCTQTLEGHGGWVQSVAFSPDGQRVASGSSDKTIKIWDTASGTCTQTLE 1216 Query: 389 PEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 + +++S DG + +G +D TI+I+ Sbjct: 1217 GHGG-------WVQSVAFSPDGQRVASGSSDNTIKIW 1246 Score = 86.7 bits (213), Expect = 4e-17 Identities = 56/165 (33%), Positives = 85/165 (51%), Gaps = 2/165 (1%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G G V V FSP+ + SGS D+++K+W+ + TL+GHGG+V +V SPDG Sbjct: 1007 GHGGSVWSVAFSPDG--QRVASGSDDKTIKIWDTASGTCTQTLEGHGGWVQSVVFSPDGQ 1064 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQD-SIKIWDLES 364 ASG D +WD G +L+ G + S+ FSP+ + + + D +IKIWD S Sbjct: 1065 RVASGSDDHTIKIWDAVSGTCTQTLEGHGDSVWSVAFSPDGQRVASGSIDGTIKIWDAAS 1124 Query: 365 KHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 Q L + +++S DG + +G DGTI+I+ Sbjct: 1125 GTCTQTLEGHGG-------WVHSVAFSPDGQRVASGSIDGTIKIW 1162 Score = 85.1 bits (209), Expect = 1e-16 Identities = 55/160 (34%), Positives = 82/160 (51%), Gaps = 2/160 (1%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 V V FSP+ + SGS D+++K+W+ + TL+GHGG V +VA SPDG ASG Sbjct: 970 VLSVAFSPDG--QRVASGSGDKTIKIWDTASGTCTQTLEGHGGSVWSVAFSPDGQRVASG 1027 Query: 206 GKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQ 379 D +WD G +L+ G + S+ FSP+ + + + D +IKIWD S Q Sbjct: 1028 SDDKTIKIWDTASGTCTQTLEGHGGWVQSVVFSPDGQRVASGSDDHTIKIWDAVSGTCTQ 1087 Query: 380 DLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 L +++S DG + +G DGTI+I+ Sbjct: 1088 TLEGHGD-------SVWSVAFSPDGQRVASGSIDGTIKIW 1120 Score = 84.3 bits (207), Expect = 2e-16 Identities = 57/165 (34%), Positives = 84/165 (50%), Gaps = 2/165 (1%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G G V V FSP+ + SGS D+++K+W+ + TL+GHGG V +VA SPDG Sbjct: 881 GHGGSVWSVAFSPDR--ERVASGSDDKTIKIWDAASGTCTQTLEGHGGRVQSVAFSPDGQ 938 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQD-SIKIWDLES 364 ASG D +WD G +L+ GS + S+ FSP+ + + + D +IKIWD S Sbjct: 939 RVASGSDDHTIKIWDAASGTCTQTLEGHGSSVLSVAFSPDGQRVASGSGDKTIKIWDTAS 998 Query: 365 KHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 Q L +++S DG + +G D TI+I+ Sbjct: 999 GTCTQTLEGHGG-------SVWSVAFSPDGQRVASGSDDKTIKIW 1036 Score = 79.0 bits (193), Expect = 9e-15 Identities = 39/96 (40%), Positives = 53/96 (55%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G GWV V FSP+ + SGS D+++K+W+ + TL+GHGG+V +VA SPDG Sbjct: 1175 GHGGWVQSVAFSPDG--QRVASGSSDKTIKIWDTASGTCTQTLEGHGGWVQSVAFSPDGQ 1232 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCF 298 ASG D +WD G +L+ GS L F Sbjct: 1233 RVASGSSDNTIKIWDTASGTCTQTLNVGSTATCLSF 1268 Score = 75.9 bits (185), Expect = 7e-14 Identities = 51/146 (34%), Positives = 77/146 (52%), Gaps = 2/146 (1%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 + SGS D+++K+W+ + TL+GHGG V +VA SPD ASG D +WD G Sbjct: 856 VASGSDDKTIKIWDTASGTGTQTLEGHGGSVWSVAFSPDRERVASGSDDKTIKIWDAASG 915 Query: 248 KRLYSLDA-GSIINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQDLRPEVPVSSKQML 421 +L+ G + S+ FSP+ + + + D +IKIWD S Q L E SS Sbjct: 916 TCTQTLEGHGGRVQSVAFSPDGQRVASGSDDHTIKIWDAASGTCTQTL--EGHGSS---- 969 Query: 422 YCTCLSWSADGSTLYAGYTDGTIRIY 499 +++S DG + +G D TI+I+ Sbjct: 970 -VLSVAFSPDGQRVASGSGDKTIKIW 994 Score = 63.2 bits (152), Expect = 5e-10 Identities = 47/162 (29%), Positives = 72/162 (44%), Gaps = 2/162 (1%) Frame = +2 Query: 20 GWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCA 199 GW+S + ++V W+ + TL+GHG V +VA S DG A Sbjct: 818 GWISTI---------SVVEAEWNACTQ-----------TLEGHGSSVLSVAFSADGQRVA 857 Query: 200 SGGKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQD-SIKIWDLESKHI 373 SG D +WD G +L+ G + S+ FSP+R + + + D +IKIWD S Sbjct: 858 SGSDDKTIKIWDTASGTGTQTLEGHGGSVWSVAFSPDRERVASGSDDKTIKIWDAASGTC 917 Query: 374 VQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 Q L +++S DG + +G D TI+I+ Sbjct: 918 TQTLEGHGG-------RVQSVAFSPDGQRVASGSDDHTIKIW 952
>WDS_DROME (Q9V3J8) Protein will die slowly| Length = 361 Score = 82.0 bits (201), Expect = 1e-15 Identities = 54/170 (31%), Positives = 86/170 (50%), Gaps = 4/170 (2%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG 187 +G + +V C F+P + IVSGS+D SV++W++ K TL H VSAV + DG Sbjct: 153 KGHSNYVFCCNFNPQS--NLIVSGSFDESVRIWDVRTGKCLKTLPAHSDPVSAVHFNRDG 210 Query: 188 SLCASGGKDGVTLLWDLTEGKRLYSL--DAGSIINSLCFSPNRYWLCAATQD-SIKIWDL 358 SL S DG+ +WD G+ L +L D ++ + FSPN ++ AAT D ++K+WD Sbjct: 211 SLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDY 270 Query: 359 ESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGST-LYAGYTDGTIRIYKI 505 ++ K YC ++S G + +G D + I+ + Sbjct: 271 SKGKCLKTY-----TGHKNEKYCIFANFSVTGGKWIVSGSEDNMVYIWNL 315 Score = 72.0 bits (175), Expect = 1e-12 Identities = 52/165 (31%), Positives = 82/165 (49%), Gaps = 2/165 (1%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G T VS V+FSPN + S S D+ +K+W + K T+ GH +S VA S D Sbjct: 70 GHTKAVSAVKFSPNG--EWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSR 127 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLC-FSPNRYWLCAATQD-SIKIWDLES 364 L SG D +W+L+ GK L +L S C F+P + + + D S++IWD+ + Sbjct: 128 LLVSGSDDKTLKVWELSTGKSLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRT 187 Query: 365 KHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 ++ L P S + + + ++ DGS + + DG RI+ Sbjct: 188 GKCLKTL----PAHSDPV---SAVHFNRDGSLIVSSSYDGLCRIW 225 Score = 65.5 bits (158), Expect = 1e-10 Identities = 45/153 (29%), Positives = 78/153 (50%), Gaps = 6/153 (3%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 +VSGS D+++KVW L+ K TL GH YV +P +L SG D +WD+ G Sbjct: 129 LVSGSDDKTLKVWELSTGKSLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRTG 188 Query: 248 KRLYSLDAGS-IINSLCFSPNRYWLCAATQDSI-KIWDLES----KHIVQDLRPEVPVSS 409 K L +L A S ++++ F+ + + +++ D + +IWD S K ++ D P V Sbjct: 189 KCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPV---- 244 Query: 410 KQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 + + +S +G + A D T++++ S Sbjct: 245 ------SFVKFSPNGKYILAATLDNTLKLWDYS 271 Score = 49.3 bits (116), Expect = 7e-06 Identities = 33/132 (25%), Positives = 65/132 (49%), Gaps = 2/132 (1%) Frame = +2 Query: 116 NCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLDAGSI-INSL 292 N L+ TL GH VSAV SP+G AS D + +W +GK ++ + I+ + Sbjct: 61 NYTLKFTLAGHTKAVSAVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDV 120 Query: 293 CFSPNRYWLCAATQD-SIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYA 469 +S + L + + D ++K+W+L + ++ L+ Y C +++ + + + Sbjct: 121 AWSSDSRLLVSGSDDKTLKVWELSTGKSLKTLK-------GHSNYVFCCNFNPQSNLIVS 173 Query: 470 GYTDGTIRIYKI 505 G D ++RI+ + Sbjct: 174 GSFDESVRIWDV 185 Score = 34.3 bits (77), Expect = 0.25 Identities = 24/66 (36%), Positives = 31/66 (46%), Gaps = 6/66 (9%) Frame = +2 Query: 53 NFAPT----IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGG--KD 214 NF+ T IVSGS D V +WNL + ++ L GH V A P ++ AS D Sbjct: 292 NFSVTGGKWIVSGSEDNMVYIWNLQSKEVVQKLQGHTDTVLCTACHPTENIIASAALEND 351 Query: 215 GVTLLW 232 LW Sbjct: 352 KTIKLW 357
>WDR5_MOUSE (P61965) WD-repeat protein 5 (BMP2-induced 3-kb gene protein)| (WD-repeat protein BIG-3) Length = 334 Score = 82.0 bits (201), Expect = 1e-15 Identities = 54/170 (31%), Positives = 86/170 (50%), Gaps = 4/170 (2%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG 187 +G + +V C F+P + IVSGS+D SV++W++ K TL H VSAV + DG Sbjct: 126 KGHSNYVFCCNFNPQS--NLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDG 183 Query: 188 SLCASGGKDGVTLLWDLTEGKRLYSL--DAGSIINSLCFSPNRYWLCAATQD-SIKIWDL 358 SL S DG+ +WD G+ L +L D ++ + FSPN ++ AAT D ++K+WD Sbjct: 184 SLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDY 243 Query: 359 ESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGST-LYAGYTDGTIRIYKI 505 ++ K YC ++S G + +G D + I+ + Sbjct: 244 SKGKCLKTY-----TGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNL 288 Score = 70.9 bits (172), Expect = 2e-12 Identities = 51/165 (30%), Positives = 83/165 (50%), Gaps = 2/165 (1%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G T VS V+FSPN + S S D+ +K+W + K T+ GH +S VA S D + Sbjct: 43 GHTKAVSSVKFSPNG--EWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSN 100 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLC-FSPNRYWLCAATQD-SIKIWDLES 364 L S D +WD++ GK L +L S C F+P + + + D S++IWD+++ Sbjct: 101 LLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKT 160 Query: 365 KHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 ++ L P S + + + ++ DGS + + DG RI+ Sbjct: 161 GKCLKTL----PAHSDPV---SAVHFNRDGSLIVSSSYDGLCRIW 198 Score = 62.8 bits (151), Expect = 6e-10 Identities = 42/153 (27%), Positives = 79/153 (51%), Gaps = 6/153 (3%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 +VS S D+++K+W++++ K TL GH YV +P +L SG D +WD+ G Sbjct: 102 LVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTG 161 Query: 248 KRLYSLDAGS-IINSLCFSPNRYWLCAATQDSI-KIWDLES----KHIVQDLRPEVPVSS 409 K L +L A S ++++ F+ + + +++ D + +IWD S K ++ D P V Sbjct: 162 KCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPV---- 217 Query: 410 KQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 + + +S +G + A D T++++ S Sbjct: 218 ------SFVKFSPNGKYILAATLDNTLKLWDYS 244 Score = 52.0 bits (123), Expect = 1e-06 Identities = 35/132 (26%), Positives = 66/132 (50%), Gaps = 2/132 (1%) Frame = +2 Query: 116 NCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLDAGSI-INSL 292 N L+ TL GH VS+V SP+G AS D + +W +GK ++ + I+ + Sbjct: 34 NYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDV 93 Query: 293 CFSPNRYWLCAATQD-SIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYA 469 +S + L +A+ D ++KIWD+ S ++ L+ Y C +++ + + + Sbjct: 94 AWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLK-------GHSNYVFCCNFNPQSNLIVS 146 Query: 470 GYTDGTIRIYKI 505 G D ++RI+ + Sbjct: 147 GSFDESVRIWDV 158 Score = 34.7 bits (78), Expect = 0.19 Identities = 24/66 (36%), Positives = 31/66 (46%), Gaps = 6/66 (9%) Frame = +2 Query: 53 NFAPT----IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGG--KD 214 NF+ T IVSGS D V +WNL ++ L GH V + A P ++ AS D Sbjct: 265 NFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALEND 324 Query: 215 GVTLLW 232 LW Sbjct: 325 KTIKLW 330
>WDR5_HUMAN (P61964) WD-repeat protein 5 (BMP2-induced 3-kb gene protein)| Length = 334 Score = 82.0 bits (201), Expect = 1e-15 Identities = 54/170 (31%), Positives = 86/170 (50%), Gaps = 4/170 (2%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG 187 +G + +V C F+P + IVSGS+D SV++W++ K TL H VSAV + DG Sbjct: 126 KGHSNYVFCCNFNPQS--NLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDG 183 Query: 188 SLCASGGKDGVTLLWDLTEGKRLYSL--DAGSIINSLCFSPNRYWLCAATQD-SIKIWDL 358 SL S DG+ +WD G+ L +L D ++ + FSPN ++ AAT D ++K+WD Sbjct: 184 SLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDY 243 Query: 359 ESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGST-LYAGYTDGTIRIYKI 505 ++ K YC ++S G + +G D + I+ + Sbjct: 244 SKGKCLKTY-----TGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNL 288 Score = 70.9 bits (172), Expect = 2e-12 Identities = 51/165 (30%), Positives = 83/165 (50%), Gaps = 2/165 (1%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G T VS V+FSPN + S S D+ +K+W + K T+ GH +S VA S D + Sbjct: 43 GHTKAVSSVKFSPNG--EWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSN 100 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLC-FSPNRYWLCAATQD-SIKIWDLES 364 L S D +WD++ GK L +L S C F+P + + + D S++IWD+++ Sbjct: 101 LLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKT 160 Query: 365 KHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 ++ L P S + + + ++ DGS + + DG RI+ Sbjct: 161 GKCLKTL----PAHSDPV---SAVHFNRDGSLIVSSSYDGLCRIW 198 Score = 62.8 bits (151), Expect = 6e-10 Identities = 42/153 (27%), Positives = 79/153 (51%), Gaps = 6/153 (3%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 +VS S D+++K+W++++ K TL GH YV +P +L SG D +WD+ G Sbjct: 102 LVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTG 161 Query: 248 KRLYSLDAGS-IINSLCFSPNRYWLCAATQDSI-KIWDLES----KHIVQDLRPEVPVSS 409 K L +L A S ++++ F+ + + +++ D + +IWD S K ++ D P V Sbjct: 162 KCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPV---- 217 Query: 410 KQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 + + +S +G + A D T++++ S Sbjct: 218 ------SFVKFSPNGKYILAATLDNTLKLWDYS 244 Score = 52.0 bits (123), Expect = 1e-06 Identities = 35/132 (26%), Positives = 66/132 (50%), Gaps = 2/132 (1%) Frame = +2 Query: 116 NCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLDAGSI-INSL 292 N L+ TL GH VS+V SP+G AS D + +W +GK ++ + I+ + Sbjct: 34 NYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDV 93 Query: 293 CFSPNRYWLCAATQD-SIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYA 469 +S + L +A+ D ++KIWD+ S ++ L+ Y C +++ + + + Sbjct: 94 AWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLK-------GHSNYVFCCNFNPQSNLIVS 146 Query: 470 GYTDGTIRIYKI 505 G D ++RI+ + Sbjct: 147 GSFDESVRIWDV 158 Score = 34.7 bits (78), Expect = 0.19 Identities = 24/66 (36%), Positives = 31/66 (46%), Gaps = 6/66 (9%) Frame = +2 Query: 53 NFAPT----IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGG--KD 214 NF+ T IVSGS D V +WNL ++ L GH V + A P ++ AS D Sbjct: 265 NFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALEND 324 Query: 215 GVTLLW 232 LW Sbjct: 325 KTIKLW 330
>GBB3_MOUSE (Q61011) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 3 (Transducin beta chain 3) Length = 340 Score = 80.9 bits (198), Expect = 2e-15 Identities = 53/165 (32%), Positives = 84/165 (50%), Gaps = 4/165 (2%) Frame = +2 Query: 17 TGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLC 196 TG++SC RF +N IV+ S D + +W++ + + GH G ++AVSPD L Sbjct: 143 TGYLSCCRFLDDN---NIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDYKLF 199 Query: 197 ASGGKDGVTLLWDLTEGK-RLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLESKH 370 SG D LWD+ EG R S IN++CF PN +C + D S +++DL + Sbjct: 200 ISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQ 259 Query: 371 IVQDLRPEVPVSSKQMLYC--TCLSWSADGSTLYAGYTDGTIRIY 499 E+ S++ + C T +++S G L+AGY D ++ Sbjct: 260 -------ELTAYSQESIICGITSVAFSLSGRLLFAGYDDFNCNVW 297 Score = 35.4 bits (80), Expect = 0.11 Identities = 17/56 (30%), Positives = 27/56 (48%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWD 235 + +G D + VW+ C+ L GH VS + V+ DG A+G D +W+ Sbjct: 285 LFAGYDDFNCNVWDSLKCERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340 Score = 33.9 bits (76), Expect = 0.32 Identities = 19/84 (22%), Positives = 42/84 (50%), Gaps = 2/84 (2%) Frame = +2 Query: 122 KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLD-AGSIINSLCF 298 + R TL GH + A+ + D L S +DG ++WD +++++ S + + + Sbjct: 46 RTRRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAY 105 Query: 299 SPN-RYWLCAATQDSIKIWDLESK 367 +P+ + C + I++L+S+ Sbjct: 106 APSGNFVACGGLDNMCSIYNLKSR 129 Score = 30.4 bits (67), Expect = 3.6 Identities = 26/104 (25%), Positives = 46/104 (44%), Gaps = 5/104 (4%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL--T 241 +VS S D + VW+ + +V A +P G+ A GG D + +++L Sbjct: 70 LVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSIYNLKSR 129 Query: 242 EG--KRLYSLDAGSIINSLC-FSPNRYWLCAATQDSIKIWDLES 364 EG K L A + S C F + + ++ + +WD+E+ Sbjct: 130 EGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCALWDIET 173
>GBB3_CANFA (P79147) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 3 (Transducin beta chain 3) Length = 340 Score = 80.5 bits (197), Expect = 3e-15 Identities = 54/165 (32%), Positives = 83/165 (50%), Gaps = 4/165 (2%) Frame = +2 Query: 17 TGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLC 196 TG++SC RF +N IV+ S D + +W++ + + GH G ++AVSPD L Sbjct: 143 TGYLSCCRFLDDN---NIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFKLF 199 Query: 197 ASGGKDGVTLLWDLTEGK-RLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLESKH 370 SG D LWD+ EG R S IN++CF PN +C + D S +++DL + Sbjct: 200 ISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQ 259 Query: 371 IVQDLRPEVPVSSKQMLYC--TCLSWSADGSTLYAGYTDGTIRIY 499 E+ S + + C T +++S G L+AGY D I+ Sbjct: 260 -------ELTAYSDESIICGITSVAFSLSGRLLFAGYDDFNCNIW 297 Score = 33.5 bits (75), Expect = 0.42 Identities = 19/84 (22%), Positives = 41/84 (48%), Gaps = 2/84 (2%) Frame = +2 Query: 122 KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLD-AGSIINSLCF 298 + R TL GH + A+ + D L S +DG ++WD +++++ S + + + Sbjct: 46 RTRRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAY 105 Query: 299 SPN-RYWLCAATQDSIKIWDLESK 367 +P+ + C + I+ L+S+ Sbjct: 106 APSGNFVACGGLDNMCSIYSLKSR 129 Score = 30.0 bits (66), Expect = 4.6 Identities = 15/56 (26%), Positives = 26/56 (46%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWD 235 + +G D + +W+ + L GH VS + V+ DG A+G D +W+ Sbjct: 285 LFAGYDDFNCNIWDSMKGERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKVWN 340 Score = 30.0 bits (66), Expect = 4.6 Identities = 26/104 (25%), Positives = 45/104 (43%), Gaps = 5/104 (4%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL--T 241 +VS S D + VW+ + +V A +P G+ A GG D + ++ L Sbjct: 70 LVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSIYSLKSR 129 Query: 242 EG--KRLYSLDAGSIINSLC-FSPNRYWLCAATQDSIKIWDLES 364 EG K L A + S C F + + ++ + +WD+E+ Sbjct: 130 EGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCALWDIET 173
>Y2124_ANASP (Q8YV57) Hypothetical WD-repeat protein all2124| Length = 1683 Score = 80.1 bits (196), Expect = 4e-15 Identities = 52/164 (31%), Positives = 86/164 (52%), Gaps = 2/164 (1%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 V+ V FSP+ T+ S S D +VK+WN+++ K + TL GH V V+ SPDG + AS Sbjct: 1449 VNKVNFSPDG--KTLASASRDNTVKLWNVSDGKFKKTLKGHTDEVFWVSFSPDGKIIASA 1506 Query: 206 GKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQ 379 D LWD G + SL A ++ S+ F+P+ L + + D ++K+W H++ Sbjct: 1507 SADKTIRLWDSFSGNLIKSLPAHNDLVYSVNFNPDGSMLASTSADKTVKLWRSHDGHLLH 1566 Query: 380 DLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISG 511 ++Y + S+S DG + + D T++I++I G Sbjct: 1567 TFS-----GHSNVVYSS--SFSPDGRYIASASEDKTVKIWQIDG 1603 Score = 79.0 bits (193), Expect = 9e-15 Identities = 53/164 (32%), Positives = 87/164 (53%), Gaps = 2/164 (1%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 V+ V FSP+ + S S D S+K+W+ T+ +L TL GH V V SPDG A+G Sbjct: 1158 VNNVYFSPDG--KNLASASSDHSIKLWDTTSGQLLMTLTGHSAGVITVRFSPDGQTIAAG 1215 Query: 206 GKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQ 379 +D LW +GK L +L+ +NSL FSP+ L +A+ D +IK+W + +V+ Sbjct: 1216 SEDKTVKLWHRQDGKLLKTLNGHQDWVNSLSFSPDGKTLASASADKTIKLWRIADGKLVK 1275 Query: 380 DLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISG 511 L+ ++ +++S+DG + + D TI+++ G Sbjct: 1276 TLK-----GHNDSVW--DVNFSSDGKAIASASRDNTIKLWNRHG 1312 Score = 79.0 bits (193), Expect = 9e-15 Identities = 50/147 (34%), Positives = 79/147 (53%), Gaps = 2/147 (1%) Frame = +2 Query: 65 TIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTE 244 TI SGS D+++K+W+ R TL+GH V +V+ SPDG ASGG D LW ++ Sbjct: 1086 TIASGSLDKTIKLWSRDGRLFR-TLNGHEDAVYSVSFSPDGQTIASGGSDKTIKLWQTSD 1144 Query: 245 GKRLYSLDA-GSIINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQDLRPEVPVSSKQM 418 G L ++ +N++ FSP+ L +A+ D SIK+WD S ++ L + Sbjct: 1145 GTLLKTITGHEQTVNNVYFSPDGKNLASASSDHSIKLWDTTSGQLLMTL-------TGHS 1197 Query: 419 LYCTCLSWSADGSTLYAGYTDGTIRIY 499 + +S DG T+ AG D T++++ Sbjct: 1198 AGVITVRFSPDGQTIAAGSEDKTVKLW 1224 Score = 78.6 bits (192), Expect = 1e-14 Identities = 52/163 (31%), Positives = 86/163 (52%), Gaps = 2/163 (1%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 V V FSP+ TI SG D+++K+W ++ L T+ GH V+ V SPDG AS Sbjct: 1116 VYSVSFSPDG--QTIASGGSDKTIKLWQTSDGTLLKTITGHEQTVNNVYFSPDGKNLASA 1173 Query: 206 GKDGVTLLWDLTEGKRLYSLDAGSI-INSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQ 379 D LWD T G+ L +L S + ++ FSP+ + A ++D ++K+W + +++ Sbjct: 1174 SSDHSIKLWDTTSGQLLMTLTGHSAGVITVRFSPDGQTIAAGSEDKTVKLWHRQDGKLLK 1233 Query: 380 DLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 L + + LS+S DG TL + D TI++++I+ Sbjct: 1234 TL-------NGHQDWVNSLSFSPDGKTLASASADKTIKLWRIA 1269 Score = 68.2 bits (165), Expect = 2e-11 Identities = 41/117 (35%), Positives = 69/117 (58%), Gaps = 2/117 (1%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G + V VRFSP+ TI +GS D++VK+W+ + KL TL+GH +V++++ SPDG Sbjct: 1195 GHSAGVITVRFSPDG--QTIAAGSEDKTVKLWHRQDGKLLKTLNGHQDWVNSLSFSPDGK 1252 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQD-SIKIWD 355 AS D LW + +GK + +L + + FS + + +A++D +IK+W+ Sbjct: 1253 TLASASADKTIKLWRIADGKLVKTLKGHNDSVWDVNFSSDGKAIASASRDNTIKLWN 1309 Score = 67.4 bits (163), Expect = 3e-11 Identities = 44/158 (27%), Positives = 86/158 (54%), Gaps = 2/158 (1%) Frame = +2 Query: 35 VRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKD 214 + F+P I S + D++VK+W + + K TL GH V+ V SPDG AS +D Sbjct: 1410 ISFTPQG--DLIASANADKTVKIWRVRDGKALKTLIGHDNEVNKVNFSPDGKTLASASRD 1467 Query: 215 GVTLLWDLTEGKRLYSLDAGS-IINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQDLR 388 LW++++GK +L + + + FSP+ + +A+ D +I++WD S ++++ L Sbjct: 1468 NTVKLWNVSDGKFKKTLKGHTDEVFWVSFSPDGKIIASASADKTIRLWDSFSGNLIKSL- 1526 Query: 389 PEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYK 502 + ++Y ++++ DGS L + D T+++++ Sbjct: 1527 ----PAHNDLVY--SVNFNPDGSMLASTSADKTVKLWR 1558 Score = 63.2 bits (152), Expect = 5e-10 Identities = 47/167 (28%), Positives = 79/167 (47%), Gaps = 1/167 (0%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G +G V V F P++ I S S D ++++W L G+ G V AV+ DGS Sbjct: 1320 GHSGGVYAVNFLPDS--NIIASASLDNTIRLWQRPLISPLEVLAGNSG-VYAVSFLHDGS 1376 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLESK 367 + A+ G DG LW +G L +L I + F+P + +A D ++KIW + Sbjct: 1377 IIATAGADGNIQLWHSQDGSLLKTLPGNKAIYGISFTPQGDLIASANADKTVKIWRVRDG 1436 Query: 368 HIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 ++ L +K +++S DG TL + D T++++ +S Sbjct: 1437 KALKTLIGHDNEVNK-------VNFSPDGKTLASASRDNTVKLWNVS 1476 Score = 39.7 bits (91), Expect = 0.006 Identities = 25/85 (29%), Positives = 41/85 (48%), Gaps = 3/85 (3%) Frame = +2 Query: 50 NNFAPT---IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGV 220 ++F+P I S S D++VK+W + L TL H V + SPDG SG D Sbjct: 1578 SSFSPDGRYIASASEDKTVKIWQIDG-HLLTTLPQHQAGVMSAIFSPDGKTLISGSLDTT 1636 Query: 221 TLLWDLTEGKRLYSLDAGSIINSLC 295 T +W + ++ + +++ S C Sbjct: 1637 TKIWRF-DSQQAKTSQMNTLVMSAC 1660
>GBB3_RAT (P52287) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 3 (Transducin beta chain 3) Length = 340 Score = 80.1 bits (196), Expect = 4e-15 Identities = 53/165 (32%), Positives = 83/165 (50%), Gaps = 4/165 (2%) Frame = +2 Query: 17 TGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLC 196 TG++SC RF +N IV+ S D + +W++ + + GH G ++AVSPD L Sbjct: 143 TGYLSCCRFLDDN---NIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDYKLF 199 Query: 197 ASGGKDGVTLLWDLTEGK-RLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLESKH 370 SG D LWD+ EG R S IN++CF PN +C + D S +++DL + Sbjct: 200 ISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQ 259 Query: 371 IVQDLRPEVPVSSKQMLYC--TCLSWSADGSTLYAGYTDGTIRIY 499 E+ S + + C T +++S G L+AGY D ++ Sbjct: 260 -------ELTAYSHESIICGITSVAFSLSGRLLFAGYDDFNCNVW 297 Score = 35.8 bits (81), Expect = 0.085 Identities = 17/56 (30%), Positives = 27/56 (48%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWD 235 + +G D + VW+ C+ L GH VS + V+ DG A+G D +W+ Sbjct: 285 LFAGYDDFNCNVWDSLKCERVGVLSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340 Score = 33.5 bits (75), Expect = 0.42 Identities = 19/84 (22%), Positives = 41/84 (48%), Gaps = 2/84 (2%) Frame = +2 Query: 122 KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLD-AGSIINSLCF 298 + R TL GH + A+ + D L S +DG ++WD +++++ S + + + Sbjct: 46 RTRRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAY 105 Query: 299 SPN-RYWLCAATQDSIKIWDLESK 367 +P+ + C + I+ L+S+ Sbjct: 106 APSGNFVACGGLDNMCSIYSLKSR 129 Score = 30.0 bits (66), Expect = 4.6 Identities = 26/104 (25%), Positives = 45/104 (43%), Gaps = 5/104 (4%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL--T 241 +VS S D + VW+ + +V A +P G+ A GG D + ++ L Sbjct: 70 LVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSIYSLKSR 129 Query: 242 EG--KRLYSLDAGSIINSLC-FSPNRYWLCAATQDSIKIWDLES 364 EG K L A + S C F + + ++ + +WD+E+ Sbjct: 130 EGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCALWDIET 173
>YKY4_CAEEL (Q17963) Hypothetical WD-repeat protein C14B1.4| Length = 376 Score = 79.7 bits (195), Expect = 5e-15 Identities = 52/170 (30%), Positives = 85/170 (50%), Gaps = 4/170 (2%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG 187 +G +V C F+P + +VSGS+D SV++W++ TL H VSAV+ + DG Sbjct: 168 KGHNNYVFCCNFNPQS--SLVVSGSFDESVRIWDVKTGMCIKTLPAHSDPVSAVSFNRDG 225 Query: 188 SLCASGGKDGVTLLWDLTEGKRLYSL--DAGSIINSLCFSPNRYWLCAATQDS-IKIWDL 358 SL ASG DG+ +WD G+ + +L D + + FSPN ++ A+ DS +K+WD Sbjct: 226 SLIASGSYDGLVRIWDTANGQCIKTLVDDENPPVAFVKFSPNGKYILASNLDSTLKLWDF 285 Query: 359 ESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGST-LYAGYTDGTIRIYKI 505 ++ + YC ++S G + +G D I I+ + Sbjct: 286 SKGKTLKQY-----TGHENSKYCIFANFSVTGGKWIISGSEDCKIYIWNL 330 Score = 58.5 bits (140), Expect = 1e-08 Identities = 39/153 (25%), Positives = 74/153 (48%), Gaps = 6/153 (3%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 +VS S D+++K++ + ++ TL GH YV +P SL SG D +WD+ G Sbjct: 144 VVSASDDKTLKIFEIVTSRMTKTLKGHNNYVFCCNFNPQSSLVVSGSFDESVRIWDVKTG 203 Query: 248 KRLYSLDAGS-IINSLCFSPNRYWLCAATQDS-IKIWDLES----KHIVQDLRPEVPVSS 409 + +L A S ++++ F+ + + + + D ++IWD + K +V D P V Sbjct: 204 MCIKTLPAHSDPVSAVSFNRDGSLIASGSYDGLVRIWDTANGQCIKTLVDDENPPV---- 259 Query: 410 KQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 + +S +G + A D T++++ S Sbjct: 260 ------AFVKFSPNGKYILASNLDSTLKLWDFS 286 Score = 56.6 bits (135), Expect = 5e-08 Identities = 43/165 (26%), Positives = 81/165 (49%), Gaps = 2/165 (1%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G T +S +FSP + + S D++VK+WN+ + TL GH V+ +A S D Sbjct: 85 GHTKSISSAKFSP--CGKYLGTSSADKTVKIWNMDHMICERTLTGHKLGVNDIAWSSDSR 142 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLC-FSPNRYWLCAATQD-SIKIWDLES 364 S D ++++ + +L + C F+P + + + D S++IWD+++ Sbjct: 143 CVVSASDDKTLKIFEIVTSRMTKTLKGHNNYVFCCNFNPQSSLVVSGSFDESVRIWDVKT 202 Query: 365 KHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 ++ L P S + + +S++ DGS + +G DG +RI+ Sbjct: 203 GMCIKTL----PAHSDPV---SAVSFNRDGSLIASGSYDGLVRIW 240 Score = 44.3 bits (103), Expect = 2e-04 Identities = 29/132 (21%), Positives = 63/132 (47%), Gaps = 2/132 (1%) Frame = +2 Query: 116 NCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLDAGSI-INSL 292 N KL CTL+GH +S+ SP G + D +W++ +L + +N + Sbjct: 76 NYKLMCTLEGHTKSISSAKFSPCGKYLGTSSADKTVKIWNMDHMICERTLTGHKLGVNDI 135 Query: 293 CFSPNRYWLCAATQD-SIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYA 469 +S + + +A+ D ++KI+++ + + + L+ Y C +++ S + + Sbjct: 136 AWSSDSRCVVSASDDKTLKIFEIVTSRMTKTLK-------GHNNYVFCCNFNPQSSLVVS 188 Query: 470 GYTDGTIRIYKI 505 G D ++RI+ + Sbjct: 189 GSFDESVRIWDV 200 Score = 31.6 bits (70), Expect = 1.6 Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 4/55 (7%) Frame = +2 Query: 53 NFAPT----IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 NF+ T I+SGS D + +WNL ++ L+GH V A P ++ ASG Sbjct: 307 NFSVTGGKWIISGSEDCKIYIWNLQTREIVQCLEGHTQPVLASDCHPVQNIIASG 361
>GBB3_HUMAN (P16520) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 3 (Transducin beta chain 3) Length = 340 Score = 79.3 bits (194), Expect = 7e-15 Identities = 53/165 (32%), Positives = 84/165 (50%), Gaps = 4/165 (2%) Frame = +2 Query: 17 TGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLC 196 TG++SC RF +N IV+ S D + +W++ + + GH G ++AVSPD +L Sbjct: 143 TGYLSCCRFLDDN---NIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLF 199 Query: 197 ASGGKDGVTLLWDLTEGK-RLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLESKH 370 SG D LWD+ EG R S IN++CF PN +C + D S +++DL + Sbjct: 200 ISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQ 259 Query: 371 IVQDLRPEVPVSSKQMLYC--TCLSWSADGSTLYAGYTDGTIRIY 499 E+ S + + C T +++S G L+AGY D ++ Sbjct: 260 -------ELICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVW 297 Score = 33.5 bits (75), Expect = 0.42 Identities = 19/84 (22%), Positives = 42/84 (50%), Gaps = 2/84 (2%) Frame = +2 Query: 122 KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLD-AGSIINSLCF 298 + R TL GH + A+ + D L S +DG ++WD +++++ S + + + Sbjct: 46 RTRRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAY 105 Query: 299 SPN-RYWLCAATQDSIKIWDLESK 367 +P+ + C + I++L+S+ Sbjct: 106 APSGNFVACGGLDNMCSIYNLKSR 129 Score = 31.6 bits (70), Expect = 1.6 Identities = 16/56 (28%), Positives = 26/56 (46%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWD 235 + +G D + VW+ + L GH VS + V+ DG A+G D +W+ Sbjct: 285 LFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
>SWD3_SCHPO (O43017) Set1 complex component swd3 (Set1C component swd3)| (COMPASS component swd3) (Complex proteins associated with set1 protein swd3) Length = 380 Score = 79.3 bits (194), Expect = 7e-15 Identities = 42/127 (33%), Positives = 73/127 (57%), Gaps = 3/127 (2%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG 187 +G T +VS + F+P +VSGSWD +V++WNL + L H + +V++S DG Sbjct: 135 KGHTNYVSSIDFNP--LGTLLVSGSWDETVRIWNLQDGTCLRMLPAHSEPIISVSISADG 192 Query: 188 SLCASGGKDGVTLLWDLTEGKRLYSL--DAGSIINSLCFSPNRYWLCAATQDS-IKIWDL 358 +LCA+ DG+ +WD+ G+ L +L +++L F+ NR +L + +S I++WD Sbjct: 193 TLCATASYDGMARIWDVLSGQCLKTLVEPINVPLSNLQFTENRKYLLVSNLNSQIRLWDY 252 Query: 359 ESKHIVQ 379 +V+ Sbjct: 253 RRNRVVR 259 Score = 58.5 bits (140), Expect = 1e-08 Identities = 45/162 (27%), Positives = 78/162 (48%), Gaps = 2/162 (1%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 V+CV SPN I + S D ++K+W+ +L CTL GH +S V + AS Sbjct: 57 VTCVSVSPNK--RWIATSSSDGTIKIWSALTFRLECTLFGHYRGISQVKWATGSKYLASA 114 Query: 206 GKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQ 379 D +WD + + L + ++S+ F+P L + + D +++IW+L+ ++ Sbjct: 115 SDDKTIRIWDFEKRCSVRCLKGHTNYVSSIDFNPLGTLLVSGSWDETVRIWNLQDGTCLR 174 Query: 380 DLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 L P S+ ++ +S SADG+ DG RI+ + Sbjct: 175 ML----PAHSEPII---SVSISADGTLCATASYDGMARIWDV 209 Score = 46.6 bits (109), Expect = 5e-05 Identities = 35/127 (27%), Positives = 61/127 (48%), Gaps = 2/127 (1%) Frame = +2 Query: 131 CTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWD-LTEGKRLYSLDAGSIINSLCFSPN 307 CTL GH V+ V+VSP+ A+ DG +W LT I+ + ++ Sbjct: 48 CTLFGHEKSVTCVSVSPNKRWIATSSSDGTIKIWSALTFRLECTLFGHYRGISQVKWATG 107 Query: 308 RYWLCAATQD-SIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDG 484 +L +A+ D +I+IWD E + V+ L+ Y + + ++ G+ L +G D Sbjct: 108 SKYLASASDDKTIRIWDFEKRCSVRCLKGHTN-------YVSSIDFNPLGTLLVSGSWDE 160 Query: 485 TIRIYKI 505 T+RI+ + Sbjct: 161 TVRIWNL 167
>KTNB1_ARATH (Q8H0T9) Katanin p80 WD40-containing subunit B1 homolog 1| Length = 837 Score = 78.2 bits (191), Expect = 1e-14 Identities = 47/150 (31%), Positives = 73/150 (48%), Gaps = 2/150 (1%) Frame = +2 Query: 29 SCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGG 208 +C+ + F SGS D ++K+W++ T GH V+ + +PDG SGG Sbjct: 103 NCISVDFHPFGEFFASGSLDTNLKIWDIRKKGCIHTYKGHTRGVNVLRFTPDGRWVVSGG 162 Query: 209 KDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQD 382 +D + +WDLT GK L + I SL F P+ + L + D ++K WDLE+ ++ Sbjct: 163 EDNIVKVWDLTAGKLLTEFKSHEGQIQSLDFHPHEFLLATGSADRTVKFWDLETFELIGS 222 Query: 383 LRPEVPVSSKQMLYCTCLSWSADGSTLYAG 472 PE CLS++ DG T+ G Sbjct: 223 GGPET-------AGVRCLSFNPDGKTVLCG 245 Score = 50.1 bits (118), Expect = 4e-06 Identities = 36/163 (22%), Positives = 70/163 (42%), Gaps = 2/163 (1%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 V+C++ + + +V+G D V +W + +L GH + +V L A+G Sbjct: 19 VNCLKIGRKS-SRVLVTGGEDHKVNLWAIGKPNAILSLYGHSSGIDSVTFDASEVLVAAG 77 Query: 206 GKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSP-NRYWLCAATQDSIKIWDLESKHIVQ 379 G LWDL E K + +L S S+ F P ++ + ++KIWD+ K + Sbjct: 78 AASGTIKLWDLEEAKIVRTLTGHRSNCISVDFHPFGEFFASGSLDTNLKIWDIRKKGCIH 137 Query: 380 DLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 + L ++ DG + +G D ++++ ++ Sbjct: 138 TYKGHT-------RGVNVLRFTPDGRWVVSGGEDNIVKVWDLT 173
>Y2800_ANASP (Q8YTC2) Hypothetical WD-repeat protein alr2800| Length = 1258 Score = 77.4 bits (189), Expect = 3e-14 Identities = 53/166 (31%), Positives = 84/166 (50%), Gaps = 2/166 (1%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG 187 RG + WV V FSP+ + S D +VK+W++ + TL GH V +VA PDG Sbjct: 681 RGHSNWVRFVVFSPDG--EILASCGADENVKLWSVRDGVCIKTLTGHEHEVFSVAFHPDG 738 Query: 188 SLCASGGKDGVTLLWDLTEGKRLYSLDAGS-IINSLCFSPNRYWLCAATQD-SIKIWDLE 361 AS D LWD+ +G L +L + + + FSP+ L ++ D +IK+WD+ Sbjct: 739 ETLASASGDKTIKLWDIQDGTCLQTLTGHTDWVRCVAFSPDGNTLASSAADHTIKLWDVS 798 Query: 362 SKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 ++ L+ + +++SADG TL +G D TI+I+ Sbjct: 799 QGKCLRTLKSHTG-------WVRSVAFSADGQTLASGSGDRTIKIW 837 Score = 71.2 bits (173), Expect = 2e-12 Identities = 53/208 (25%), Positives = 86/208 (41%), Gaps = 44/208 (21%) Frame = +2 Query: 17 TGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLC 196 TGWV V FS + T+ SGS DR++K+WN + T GH V ++A SPD + Sbjct: 810 TGWVRSVAFSADG--QTLASGSGDRTIKIWNYHTGECLKTYIGHTNSVYSIAYSPDSKIL 867 Query: 197 ASGGKDGVTLLWD---------------------------------LTEGKRLYSLDAGS 277 SG D LWD L + RL++ G Sbjct: 868 VSGSGDRTIKLWDCQTHICIKTLHGHTNEVCSVAFSPDGQTLACVSLDQSVRLWNCRTGQ 927 Query: 278 IINS----------LCFSPNRYWLCAATQD-SIKIWDLESKHIVQDLRPEVPVSSKQMLY 424 + + + FSP+R L + + D ++K+WD ++ + L + Sbjct: 928 CLKAWYGNTDWALPVAFSPDRQILASGSNDKTVKLWDWQTGKYISSLEGHTD-------F 980 Query: 425 CTCLSWSADGSTLYAGYTDGTIRIYKIS 508 +++S D TL + TD ++R++ IS Sbjct: 981 IYGIAFSPDSQTLASASTDSSVRLWNIS 1008 Score = 71.2 bits (173), Expect = 2e-12 Identities = 48/160 (30%), Positives = 84/160 (52%), Gaps = 2/160 (1%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 V V F P+ T+ S S D+++K+W++ + TL GH +V VA SPDG+ AS Sbjct: 729 VFSVAFHPDG--ETLASASGDKTIKLWDIQDGTCLQTLTGHTDWVRCVAFSPDGNTLASS 786 Query: 206 GKDGVTLLWDLTEGKRLYSLDAGS-IINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQ 379 D LWD+++GK L +L + + + S+ FS + L + + D +IKIW+ + ++ Sbjct: 787 AADHTIKLWDVSQGKCLRTLKSHTGWVRSVAFSADGQTLASGSGDRTIKIWNYHTGECLK 846 Query: 380 DLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 + +Y +++S D L +G D TI+++ Sbjct: 847 TY-----IGHTNSVY--SIAYSPDSKILVSGSGDRTIKLW 879 Score = 70.9 bits (172), Expect = 2e-12 Identities = 57/184 (30%), Positives = 88/184 (47%), Gaps = 3/184 (1%) Frame = +2 Query: 17 TGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLC 196 T WV V F P I +GS D +VK+WN++ + TL H + +A SPDG L Sbjct: 1020 TDWVYAVVFHPQG--KIIATGSADCTVKLWNISTGQCLKTLSEHSDKILGMAWSPDGQLL 1077 Query: 197 ASGGKDGVTLLWDLTEGKRLYSLDAGS-IINSLCFSPNRYWLC-AATQDSIKIWDLESKH 370 AS D LWD G+ + L S + S FSPN + +T ++KIWD + Sbjct: 1078 ASASADQSVRLWDCCTGRCVGILRGHSNRVYSAIFSPNGEIIATCSTDQTVKIWDWQQGK 1137 Query: 371 IVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI-SGFSYSS*IMYLVL 547 ++ L + + +++S DG L + D T+RI+ + +G + I + L Sbjct: 1138 CLKTL-------TGHTNWVFDIAFSPDGKILASASHDQTVRIWDVNTGKCHHICIGHTHL 1190 Query: 548 VASV 559 V+SV Sbjct: 1191 VSSV 1194 Score = 70.1 bits (170), Expect = 4e-12 Identities = 42/129 (32%), Positives = 70/129 (54%), Gaps = 2/129 (1%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG 187 RG + V FSPN I + S D++VK+W+ K TL GH +V +A SPDG Sbjct: 1101 RGHSNRVYSAIFSPNG--EIIATCSTDQTVKIWDWQQGKCLKTLTGHTNWVFDIAFSPDG 1158 Query: 188 SLCASGGKDGVTLLWDLTEGK-RLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLE 361 + AS D +WD+ GK + +++S+ FSP+ + + +QD +++IW+++ Sbjct: 1159 KILASASHDQTVRIWDVNTGKCHHICIGHTHLVSSVAFSPDGEVVASGSQDQTVRIWNVK 1218 Query: 362 SKHIVQDLR 388 + +Q LR Sbjct: 1219 TGECLQILR 1227 Score = 70.1 bits (170), Expect = 4e-12 Identities = 48/165 (29%), Positives = 80/165 (48%), Gaps = 2/165 (1%) Frame = +2 Query: 20 GWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCA 199 G + FSP + + D V+VW + + KL GH +V V SPDG + A Sbjct: 643 GNILSAAFSPEG--QLLATCDTDCHVRVWEVKSGKLLLICRGHSNWVRFVVFSPDGEILA 700 Query: 200 SGGKDGVTLLWDLTEGKRLYSLDAGS-IINSLCFSPNRYWLCAATQD-SIKIWDLESKHI 373 S G D LW + +G + +L + S+ F P+ L +A+ D +IK+WD++ Sbjct: 701 SCGADENVKLWSVRDGVCIKTLTGHEHEVFSVAFHPDGETLASASGDKTIKLWDIQDGTC 760 Query: 374 VQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 +Q L + C+++S DG+TL + D TI+++ +S Sbjct: 761 LQTLTGHTD-------WVRCVAFSPDGNTLASSAADHTIKLWDVS 798 Score = 68.9 bits (167), Expect = 9e-12 Identities = 43/165 (26%), Positives = 80/165 (48%), Gaps = 2/165 (1%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G T W V FSP+ + SGS D++VK+W+ K +L+GH ++ +A SPD Sbjct: 934 GNTDWALPVAFSPDR--QILASGSNDKTVKLWDWQTGKYISSLEGHTDFIYGIAFSPDSQ 991 Query: 191 LCASGGKDGVTLLWDLTEGKRL-YSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLES 364 AS D LW+++ G+ L+ + ++ F P + + D ++K+W++ + Sbjct: 992 TLASASTDSSVRLWNISTGQCFQILLEHTDWVYAVVFHPQGKIIATGSADCTVKLWNIST 1051 Query: 365 KHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 ++ L S+ ++WS DG L + D ++R++ Sbjct: 1052 GQCLKTL-------SEHSDKILGMAWSPDGQLLASASADQSVRLW 1089 Score = 67.4 bits (163), Expect = 3e-11 Identities = 48/168 (28%), Positives = 78/168 (46%), Gaps = 2/168 (1%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G T V V FSP+ T+ S D+SV++WN + G+ + VA SPD Sbjct: 892 GHTNEVCSVAFSPDG--QTLACVSLDQSVRLWNCRTGQCLKAWYGNTDWALPVAFSPDRQ 949 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGS-IINSLCFSPNRYWLCAATQD-SIKIWDLES 364 + ASG D LWD GK + SL+ + I + FSP+ L +A+ D S+++W++ + Sbjct: 950 ILASGSNDKTVKLWDWQTGKYISSLEGHTDFIYGIAFSPDSQTLASASTDSSVRLWNIST 1009 Query: 365 KHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 Q L + + + G + G D T++++ IS Sbjct: 1010 GQCFQILLEHTD-------WVYAVVFHPQGKIIATGSADCTVKLWNIS 1050 Score = 60.1 bits (144), Expect = 4e-09 Identities = 32/87 (36%), Positives = 48/87 (55%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G T WV + FSP+ + S S D++V++W++ K GH VS+VA SPDG Sbjct: 1144 GHTNWVFDIAFSPDG--KILASASHDQTVRIWDVNTGKCHHICIGHTHLVSSVAFSPDGE 1201 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDA 271 + ASG +D +W++ G+ L L A Sbjct: 1202 VVASGSQDQTVRIWNVKTGECLQILRA 1228
>KTNB1_BRARE (Q7ZUV2) Katanin p80 WD40-containing subunit B1 homolog| Length = 694 Score = 77.0 bits (188), Expect = 3e-14 Identities = 50/160 (31%), Positives = 79/160 (49%), Gaps = 2/160 (1%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 +S + F P + SGS D ++K+W++ GH V +A SPDG AS Sbjct: 108 ISSLDFHP--MGEYLASGSVDSNIKLWDVRRKGCVFRYKGHTQAVRCLAFSPDGKWLASA 165 Query: 206 GKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQ 379 D LWDL GK + + S +N + F PN Y L + + D ++K+WDLE +++ Sbjct: 166 SDDSTVKLWDLIAGKMITEFTSHTSAVNVVQFHPNEYLLASGSADRTVKLWDLEKFNMIG 225 Query: 380 DLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 E V + ++ DGS LY+G ++ T+R+Y Sbjct: 226 SSEGETGVVRSVL-------FNPDGSCLYSG-SENTLRVY 257 Score = 53.9 bits (128), Expect = 3e-07 Identities = 39/148 (26%), Positives = 65/148 (43%), Gaps = 2/148 (1%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 + +G D V +W ++ +L GH V + + +G G LWDL Sbjct: 36 LATGGEDCRVNIWAVSKPNCIMSLTGHTSAVGCIQFNSSEERVVAGSLSGSLRLWDLEAA 95 Query: 248 KRLYSL-DAGSIINSLCFSPNRYWLCAATQDS-IKIWDLESKHIVQDLRPEVPVSSKQML 421 K L +L + I+SL F P +L + + DS IK+WD+ K V + Sbjct: 96 KILRTLMGHKASISSLDFHPMGEYLASGSVDSNIKLWDVRRKGCVFRYKGHTQA------ 149 Query: 422 YCTCLSWSADGSTLYAGYTDGTIRIYKI 505 CL++S DG L + D T++++ + Sbjct: 150 -VRCLAFSPDGKWLASASDDSTVKLWDL 176
>KTNB1_CHICK (Q5ZIU8) Katanin p80 WD40-containing subunit B1 (Katanin p80| subunit B1) (p80 katanin) Length = 657 Score = 77.0 bits (188), Expect = 3e-14 Identities = 48/147 (32%), Positives = 72/147 (48%), Gaps = 3/147 (2%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 + SGS D +K+W++ H V + SPDG AS D LWDLT G Sbjct: 119 VASGSLDTDIKLWDVRRKGCIFKYKSHTQAVRCLRFSPDGKWLASAADDHTVKLWDLTAG 178 Query: 248 KRLYSLDAGS-IINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQDLRPE-VPVSSKQM 418 K ++ S +N + F P+ Y L + + D +I+ WDLE H+V + E PV Sbjct: 179 KVMFEFTGHSGPVNVVEFHPSEYLLASGSSDRTIRFWDLEKFHVVSCIEEEATPV----- 233 Query: 419 LYCTCLSWSADGSTLYAGYTDGTIRIY 499 C+ ++ DG LY G+ D ++R+Y Sbjct: 234 ---RCILFNPDGCCLYGGFQD-SLRVY 256 Score = 52.8 bits (125), Expect = 7e-07 Identities = 39/149 (26%), Positives = 70/149 (46%), Gaps = 2/149 (1%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 + +G D V VW++ +LR L GH + ++ +S L +G + G +WDL Sbjct: 36 LATGGDDCQVNVWSV-KAQLRHELTGHTTPIESLQISAKEELIVAGSQSGSIRVWDLEAA 94 Query: 248 KRLYS-LDAGSIINSLCFSPNRYWLCAATQDS-IKIWDLESKHIVQDLRPEVPVSSKQML 421 K L + L + I SL F P ++ + + D+ IK+WD+ K + + Sbjct: 95 KILRTLLGHKANICSLDFHPYGSFVASGSLDTDIKLWDVRRKGCIFKYKSHTQA------ 148 Query: 422 YCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 CL +S DG L + D T++++ ++ Sbjct: 149 -VRCLRFSPDGKWLASAADDHTVKLWDLT 176 Score = 35.8 bits (81), Expect = 0.085 Identities = 19/70 (27%), Positives = 35/70 (50%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G +G V+ V F P+ + + SGS DR+++ W+L + ++ V + +PDG Sbjct: 186 GHSGPVNVVEFHPSEYL--LASGSSDRTIRFWDLEKFHVVSCIEEEATPVRCILFNPDGC 243 Query: 191 LCASGGKDGV 220 G +D + Sbjct: 244 CLYGGFQDSL 253
>YZLL_CAEEL (Q93847) Hypothetical WD-repeat protein K04G11.4| Length = 395 Score = 76.6 bits (187), Expect = 4e-14 Identities = 47/170 (27%), Positives = 86/170 (50%), Gaps = 4/170 (2%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG 187 +G T +V C F+P+ I SGS+D ++++W N ++ GH VS+V + DG Sbjct: 187 KGHTNYVFCCCFNPSG--TLIASGSFDETIRIWCARNGNTIFSIPGHEDPVSSVCFNRDG 244 Query: 188 SLCASGGKDGVTLLWDLTEGKRLYSL--DAGSIINSLCFSPN-RYWLCAATQDSIKIWDL 358 + ASG DG+ +WD T G + +L + I + FSPN +Y L + +++K+WD Sbjct: 245 AYLASGSYDGIVRIWDSTTGTCVKTLIDEEHPPITHVKFSPNGKYILASNLNNTLKLWDY 304 Query: 359 ESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGST-LYAGYTDGTIRIYKI 505 + ++++ + YC ++S G + +G D + I+ + Sbjct: 305 QKLRVLKEY-----TGHENSKYCVAANFSVTGGKWIVSGSEDHKVYIWNL 349 Score = 60.8 bits (146), Expect = 2e-09 Identities = 43/155 (27%), Positives = 80/155 (51%), Gaps = 2/155 (1%) Frame = +2 Query: 41 FSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGV 220 FS ++ + IVS S D+ VKV+++++ + TL GH YV +P G+L ASG D Sbjct: 154 FSWSSDSKLIVSCSDDKLVKVFDVSSGRCVKTLKGHTNYVFCCCFNPSGTLIASGSFDET 213 Query: 221 TLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQDSI-KIWDLESKHIVQDLRPE 394 +W G ++S+ ++S+CF+ + +L + + D I +IWD + V+ L E Sbjct: 214 IRIWCARNGNTIFSIPGHEDPVSSVCFNRDGAYLASGSYDGIVRIWDSTTGTCVKTLIDE 273 Query: 395 VPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 + T + +S +G + A + T++++ Sbjct: 274 ------EHPPITHVKFSPNGKYILASNLNNTLKLW 302 Score = 50.4 bits (119), Expect = 3e-06 Identities = 43/161 (26%), Positives = 83/161 (51%), Gaps = 3/161 (1%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 +S ++FSP+ + SGS D S+K+W + + TL GH ++ + S D L S Sbjct: 110 ISGIKFSPDG--RYMGSGSADCSIKIWRM-DFVYEKTLMGHRLGINEFSWSSDSKLIVSC 166 Query: 206 GKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQ 379 D + ++D++ G+ + +L + + CF+P+ + + + D +I+IW + + + Sbjct: 167 SDDKLVKVFDVSSGRCVKTLKGHTNYVFCCCFNPSGTLIASGSFDETIRIWCARNGNTIF 226 Query: 380 DL-RPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 + E PVSS + ++ DG+ L +G DG +RI+ Sbjct: 227 SIPGHEDPVSS--------VCFNRDGAYLASGSYDGIVRIW 259 Score = 37.0 bits (84), Expect = 0.038 Identities = 22/54 (40%), Positives = 28/54 (51%), Gaps = 4/54 (7%) Frame = +2 Query: 53 NFAPT----IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCAS 202 NF+ T IVSGS D V +WNL ++ TLDGH V P ++ AS Sbjct: 326 NFSVTGGKWIVSGSEDHKVYIWNLQTREILQTLDGHNTAVMCTDCHPGQNIIAS 379
>Y143_SYNY3 (P74442) Hypothetical WD-repeat protein slr0143| Length = 1191 Score = 76.3 bits (186), Expect = 6e-14 Identities = 55/169 (32%), Positives = 82/169 (48%), Gaps = 2/169 (1%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G TG + V FSPN + D++VK+W+L L+ TL GH V +V+ SPDG Sbjct: 599 GHTGSIYRVDFSPNG--KIFATAGQDQTVKIWDLDGNLLQ-TLKGHQDSVYSVSFSPDGE 655 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGS-IINSLCFSPNRYWLCAATQD-SIKIWDLES 364 + AS +D LW GK L L + ++ FSP+ L + +D I++WDL+ Sbjct: 656 ILASTSRDRTVRLWHWRSGKTLAVLGGHTKSVDDAQFSPDGQTLVSVCRDGQIRLWDLDG 715 Query: 365 KHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISG 511 I Q PEV ++W +G+ L DGT+R++ G Sbjct: 716 NLIRQFGLPEVAFFG--------VNWHPNGNLLAVAADDGTVRLWTPQG 756 Score = 56.2 bits (134), Expect = 6e-08 Identities = 36/151 (23%), Positives = 76/151 (50%), Gaps = 2/151 (1%) Frame = +2 Query: 62 PTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLT 241 P + +G ++ +WN +R ++ HG ++ + SP+G S G++G +W + Sbjct: 1010 PQLAAGDEQGNLTLWNFDGTLIR-SIVAHGDRLNQLQYSPNGKYLLSAGREGTAKIWSV- 1067 Query: 242 EGKRLYSLDAGSI-INSLCFSPNRYWLCAATQDS-IKIWDLESKHIVQDLRPEVPVSSKQ 415 EG+ L++L + + I+ + SP+ W+ A D +++WD + +LR E +S Sbjct: 1068 EGQLLHTLKSDPLPIDQIAISPDSQWIATAASDGMVRLWDQQG-----NLRGEFTSTSGS 1122 Query: 416 MLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 +L L ++ G L A +G ++ + ++ Sbjct: 1123 LL---GLDFNRQGQWLLAVAQNGDLQSWPVT 1150 Score = 50.8 bits (120), Expect = 3e-06 Identities = 42/123 (34%), Positives = 65/123 (52%), Gaps = 2/123 (1%) Frame = +2 Query: 137 LDGHGGYVSAVAVSPDGSLCASGGKDGVTLLW-DLTEGKRLYSLDAGSIINSLCFSPNRY 313 L GH V++VA+S +L AS +DG LW E R ++ GSI + FSPN Sbjct: 556 LTGHRDGVTSVAISSHKNLIASASRDGTVHLWTPQGEFLREFTGHTGSIYR-VDFSPNGK 614 Query: 314 WLCAATQD-SIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTI 490 A QD ++KIWDL+ +++Q L+ + +Y +S+S DG L + D T+ Sbjct: 615 IFATAGQDQTVKIWDLDG-NLLQTLK-----GHQDSVY--SVSFSPDGEILASTSRDRTV 666 Query: 491 RIY 499 R++ Sbjct: 667 RLW 669 Score = 49.7 bits (117), Expect = 6e-06 Identities = 44/171 (25%), Positives = 76/171 (44%), Gaps = 3/171 (1%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG 187 +G V V FSP+ + S S DR+V++W+ + K L GH V SPDG Sbjct: 639 KGHQDSVYSVSFSPDG--EILASTSRDRTVRLWHWRSGKTLAVLGGHTKSVDDAQFSPDG 696 Query: 188 SLCASGGKDGVTLLWDLTEGKRLYSLDAGSI-INSLCFSPNRYWLCAATQD-SIKIWDLE 361 S +DG LWDL +G + + + + PN L A D ++++W + Sbjct: 697 QTLVSVCRDGQIRLWDL-DGNLIRQFGLPEVAFFGVNWHPNGNLLAVAADDGTVRLWTPQ 755 Query: 362 SKHIVQDLRPEVPVS-SKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISG 511 E+ + S + T + ++ DG L++ ++G++ + SG Sbjct: 756 G---------EIKATLSGHDEFVTRVVFTPDGKQLFSSSSNGSVIHWSTSG 797 Score = 41.2 bits (95), Expect = 0.002 Identities = 31/111 (27%), Positives = 55/111 (49%), Gaps = 1/111 (0%) Frame = +2 Query: 35 VRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKD 214 +++SPN ++S + + K+W++ +L TL + +A+SPD A+ D Sbjct: 1044 LQYSPNG--KYLLSAGREGTAKIWSVEG-QLLHTLKSDPLPIDQIAISPDSQWIATAASD 1100 Query: 215 GVTLLWDLTEGKR-LYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLES 364 G+ LWD R ++ +GS++ L F+ WL A Q+ DL+S Sbjct: 1101 GMVRLWDQQGNLRGEFTSTSGSLL-GLDFNRQGQWLLAVAQNG----DLQS 1146 Score = 29.3 bits (64), Expect = 7.9 Identities = 25/103 (24%), Positives = 43/103 (41%), Gaps = 6/103 (5%) Frame = +2 Query: 77 GSWDRSVKVWN------LTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL 238 G+ + VKVW+ L N L L AVA + + A ++ +L++ Sbjct: 825 GAENNLVKVWDMSPKSDLVNLNLPAVL-------GAVAENAKTNTIALAMENEPLILFNT 877 Query: 239 TEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESK 367 R + DA ++ L FS + WL ++W L++K Sbjct: 878 KNRSRQFLSDASQNLDRLKFSADGQWLLGQRGRQWQLWQLQTK 920
>RCO1_NEUCR (P78706) Transcriptional repressor rco-1| Length = 604 Score = 74.3 bits (181), Expect = 2e-13 Identities = 45/163 (27%), Positives = 88/163 (53%), Gaps = 1/163 (0%) Frame = +2 Query: 23 WVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCAS 202 ++ V FSP+ + +G+ D+ ++VW++ + +R T GH + ++ S DG AS Sbjct: 346 YIRSVCFSPDG--KYLATGAEDKLIRVWDIQSRTIRNTFHGHEQDIYSLDFSRDGRTIAS 403 Query: 203 GGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQ 379 G D LWD+ G+ L + ++ SP++ ++ A + D S+++WD+ ++ + Sbjct: 404 GSGDRTVRLWDIETGQNTSVLSIEDGVTTVAISPDKQFVAAGSLDKSVRVWDMRG-YLAE 462 Query: 380 DLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 R E P K +Y +++S DG L +G D TI+++++S Sbjct: 463 --RLEGPDGHKDSVY--SVAFSPDGRNLVSGSLDKTIKMWELS 501 Score = 46.6 bits (109), Expect = 5e-05 Identities = 33/94 (35%), Positives = 46/94 (48%), Gaps = 15/94 (15%) Frame = +2 Query: 11 GPTGW---VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKL----------RC--TLDG 145 GP G V V FSP+ +VSGS D+++K+W L+ + RC T +G Sbjct: 466 GPDGHKDSVYSVAFSPDG--RNLVSGSLDKTIKMWELSAPRGIPSSAPPKGGRCIKTFEG 523 Query: 146 HGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 H +V +VA++PD SG KD WD G Sbjct: 524 HRDFVLSVALTPDSQWVLSGSKDRGVQFWDPRTG 557 Score = 30.4 bits (67), Expect = 3.6 Identities = 19/57 (33%), Positives = 29/57 (50%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSP 181 G +V V +P++ ++SGS DR V+ W+ + L GH V +VA SP Sbjct: 523 GHRDFVLSVALTPDS--QWVLSGSKDRGVQFWDPRTGHTQLMLQGHKNSVISVAPSP 577
>GBB1_RAT (P54311) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 74.3 bits (181), Expect = 2e-13 Identities = 52/167 (31%), Positives = 81/167 (48%), Gaps = 4/167 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G TG++SC RF +N IV+ S D + +W++ + T GH G V +++++PD Sbjct: 140 GHTGYLSCCRFLDDN---QIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTR 196 Query: 191 LCASGGKDGVTLLWDLTEGK-RLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLES 364 L SG D LWD+ EG R S IN++CF PN + D + +++DL + Sbjct: 197 LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA 256 Query: 365 KHIVQDLRPEVPVSSKQMLYC--TCLSWSADGSTLYAGYTDGTIRIY 499 E+ S + C T +S+S G L AGY D ++ Sbjct: 257 DQ-------ELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVW 296 Score = 53.5 bits (127), Expect = 4e-07 Identities = 45/167 (26%), Positives = 75/167 (44%), Gaps = 4/167 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G TG V + +P+ VSG+ D S K+W++ R T GH ++A+ P+G+ Sbjct: 181 GHTGDVMSLSLAPDT--RLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGN 238 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSI---INSLCFSPNRYWLCAATQD-SIKIWDL 358 A+G D L+DL + L + +I I S+ FS + L A D + +WD Sbjct: 239 AFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWD- 297 Query: 359 ESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 ++ R V + +CL + DG + G D ++I+ Sbjct: 298 ----ALKADRAGVLAGHDNRV--SCLGVTDDGMAVATGSWDSFLKIW 338 Score = 33.1 bits (74), Expect = 0.55 Identities = 19/84 (22%), Positives = 41/84 (48%), Gaps = 2/84 (2%) Frame = +2 Query: 122 KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLD-AGSIINSLCF 298 + R TL GH + A+ D L S +DG ++WD +++++ S + + + Sbjct: 45 RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAY 104 Query: 299 SPN-RYWLCAATQDSIKIWDLESK 367 +P+ Y C + I++L+++ Sbjct: 105 APSGNYVACGGLDNICSIYNLKTR 128 Score = 32.7 bits (73), Expect = 0.72 Identities = 16/56 (28%), Positives = 26/56 (46%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWD 235 +++G D + VW+ L GH VS + V+ DG A+G D +W+ Sbjct: 284 LLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 339
>GBB1_PONPY (Q5R5W8) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 74.3 bits (181), Expect = 2e-13 Identities = 52/167 (31%), Positives = 81/167 (48%), Gaps = 4/167 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G TG++SC RF +N IV+ S D + +W++ + T GH G V +++++PD Sbjct: 140 GHTGYLSCCRFLDDN---QIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTR 196 Query: 191 LCASGGKDGVTLLWDLTEGK-RLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLES 364 L SG D LWD+ EG R S IN++CF PN + D + +++DL + Sbjct: 197 LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA 256 Query: 365 KHIVQDLRPEVPVSSKQMLYC--TCLSWSADGSTLYAGYTDGTIRIY 499 E+ S + C T +S+S G L AGY D ++ Sbjct: 257 DQ-------ELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVW 296 Score = 53.5 bits (127), Expect = 4e-07 Identities = 45/167 (26%), Positives = 75/167 (44%), Gaps = 4/167 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G TG V + +P+ VSG+ D S K+W++ R T GH ++A+ P+G+ Sbjct: 181 GHTGDVMSLSLAPDT--RLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGN 238 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSI---INSLCFSPNRYWLCAATQD-SIKIWDL 358 A+G D L+DL + L + +I I S+ FS + L A D + +WD Sbjct: 239 AFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWD- 297 Query: 359 ESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 ++ R V + +CL + DG + G D ++I+ Sbjct: 298 ----ALKADRAGVLAGHDDRV--SCLGVTDDGMAVATGSWDSFLKIW 338 Score = 33.1 bits (74), Expect = 0.55 Identities = 19/84 (22%), Positives = 41/84 (48%), Gaps = 2/84 (2%) Frame = +2 Query: 122 KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLD-AGSIINSLCF 298 + R TL GH + A+ D L S +DG ++WD +++++ S + + + Sbjct: 45 RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAY 104 Query: 299 SPN-RYWLCAATQDSIKIWDLESK 367 +P+ Y C + I++L+++ Sbjct: 105 APSGNYVACGGLDNICSIYNLKTR 128 Score = 32.3 bits (72), Expect = 0.94 Identities = 16/56 (28%), Positives = 26/56 (46%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWD 235 +++G D + VW+ L GH VS + V+ DG A+G D +W+ Sbjct: 284 LLAGYDDFNCNVWDALKADRAGVLAGHDDRVSCLGVTDDGMAVATGSWDSFLKIWN 339
>GBB1_MOUSE (P62874) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 74.3 bits (181), Expect = 2e-13 Identities = 52/167 (31%), Positives = 81/167 (48%), Gaps = 4/167 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G TG++SC RF +N IV+ S D + +W++ + T GH G V +++++PD Sbjct: 140 GHTGYLSCCRFLDDN---QIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTR 196 Query: 191 LCASGGKDGVTLLWDLTEGK-RLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLES 364 L SG D LWD+ EG R S IN++CF PN + D + +++DL + Sbjct: 197 LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA 256 Query: 365 KHIVQDLRPEVPVSSKQMLYC--TCLSWSADGSTLYAGYTDGTIRIY 499 E+ S + C T +S+S G L AGY D ++ Sbjct: 257 DQ-------ELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVW 296 Score = 53.5 bits (127), Expect = 4e-07 Identities = 45/167 (26%), Positives = 75/167 (44%), Gaps = 4/167 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G TG V + +P+ VSG+ D S K+W++ R T GH ++A+ P+G+ Sbjct: 181 GHTGDVMSLSLAPDT--RLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGN 238 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSI---INSLCFSPNRYWLCAATQD-SIKIWDL 358 A+G D L+DL + L + +I I S+ FS + L A D + +WD Sbjct: 239 AFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWD- 297 Query: 359 ESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 ++ R V + +CL + DG + G D ++I+ Sbjct: 298 ----ALKADRAGVLAGHDNRV--SCLGVTDDGMAVATGSWDSFLKIW 338 Score = 33.1 bits (74), Expect = 0.55 Identities = 19/84 (22%), Positives = 41/84 (48%), Gaps = 2/84 (2%) Frame = +2 Query: 122 KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLD-AGSIINSLCF 298 + R TL GH + A+ D L S +DG ++WD +++++ S + + + Sbjct: 45 RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAY 104 Query: 299 SPN-RYWLCAATQDSIKIWDLESK 367 +P+ Y C + I++L+++ Sbjct: 105 APSGNYVACGGLDNICSIYNLKTR 128 Score = 32.7 bits (73), Expect = 0.72 Identities = 16/56 (28%), Positives = 26/56 (46%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWD 235 +++G D + VW+ L GH VS + V+ DG A+G D +W+ Sbjct: 284 LLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 339
>GBB1_HUMAN (P62873) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 74.3 bits (181), Expect = 2e-13 Identities = 52/167 (31%), Positives = 81/167 (48%), Gaps = 4/167 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G TG++SC RF +N IV+ S D + +W++ + T GH G V +++++PD Sbjct: 140 GHTGYLSCCRFLDDN---QIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTR 196 Query: 191 LCASGGKDGVTLLWDLTEGK-RLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLES 364 L SG D LWD+ EG R S IN++CF PN + D + +++DL + Sbjct: 197 LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA 256 Query: 365 KHIVQDLRPEVPVSSKQMLYC--TCLSWSADGSTLYAGYTDGTIRIY 499 E+ S + C T +S+S G L AGY D ++ Sbjct: 257 DQ-------ELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVW 296 Score = 53.5 bits (127), Expect = 4e-07 Identities = 45/167 (26%), Positives = 75/167 (44%), Gaps = 4/167 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G TG V + +P+ VSG+ D S K+W++ R T GH ++A+ P+G+ Sbjct: 181 GHTGDVMSLSLAPDT--RLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGN 238 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSI---INSLCFSPNRYWLCAATQD-SIKIWDL 358 A+G D L+DL + L + +I I S+ FS + L A D + +WD Sbjct: 239 AFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWD- 297 Query: 359 ESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 ++ R V + +CL + DG + G D ++I+ Sbjct: 298 ----ALKADRAGVLAGHDNRV--SCLGVTDDGMAVATGSWDSFLKIW 338 Score = 33.1 bits (74), Expect = 0.55 Identities = 19/84 (22%), Positives = 41/84 (48%), Gaps = 2/84 (2%) Frame = +2 Query: 122 KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLD-AGSIINSLCF 298 + R TL GH + A+ D L S +DG ++WD +++++ S + + + Sbjct: 45 RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAY 104 Query: 299 SPN-RYWLCAATQDSIKIWDLESK 367 +P+ Y C + I++L+++ Sbjct: 105 APSGNYVACGGLDNICSIYNLKTR 128 Score = 32.7 bits (73), Expect = 0.72 Identities = 16/56 (28%), Positives = 26/56 (46%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWD 235 +++G D + VW+ L GH VS + V+ DG A+G D +W+ Sbjct: 284 LLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 339
>GBB1_CANFA (P62872) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 74.3 bits (181), Expect = 2e-13 Identities = 52/167 (31%), Positives = 81/167 (48%), Gaps = 4/167 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G TG++SC RF +N IV+ S D + +W++ + T GH G V +++++PD Sbjct: 140 GHTGYLSCCRFLDDN---QIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTR 196 Query: 191 LCASGGKDGVTLLWDLTEGK-RLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLES 364 L SG D LWD+ EG R S IN++CF PN + D + +++DL + Sbjct: 197 LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA 256 Query: 365 KHIVQDLRPEVPVSSKQMLYC--TCLSWSADGSTLYAGYTDGTIRIY 499 E+ S + C T +S+S G L AGY D ++ Sbjct: 257 DQ-------ELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVW 296 Score = 53.5 bits (127), Expect = 4e-07 Identities = 45/167 (26%), Positives = 75/167 (44%), Gaps = 4/167 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G TG V + +P+ VSG+ D S K+W++ R T GH ++A+ P+G+ Sbjct: 181 GHTGDVMSLSLAPDT--RLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGN 238 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSI---INSLCFSPNRYWLCAATQD-SIKIWDL 358 A+G D L+DL + L + +I I S+ FS + L A D + +WD Sbjct: 239 AFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWD- 297 Query: 359 ESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 ++ R V + +CL + DG + G D ++I+ Sbjct: 298 ----ALKADRAGVLAGHDNRV--SCLGVTDDGMAVATGSWDSFLKIW 338 Score = 33.1 bits (74), Expect = 0.55 Identities = 19/84 (22%), Positives = 41/84 (48%), Gaps = 2/84 (2%) Frame = +2 Query: 122 KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLD-AGSIINSLCF 298 + R TL GH + A+ D L S +DG ++WD +++++ S + + + Sbjct: 45 RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAY 104 Query: 299 SPN-RYWLCAATQDSIKIWDLESK 367 +P+ Y C + I++L+++ Sbjct: 105 APSGNYVACGGLDNICSIYNLKTR 128 Score = 32.7 bits (73), Expect = 0.72 Identities = 16/56 (28%), Positives = 26/56 (46%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWD 235 +++G D + VW+ L GH VS + V+ DG A+G D +W+ Sbjct: 284 LLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 339
>GBB1_BOVIN (P62871) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 74.3 bits (181), Expect = 2e-13 Identities = 52/167 (31%), Positives = 81/167 (48%), Gaps = 4/167 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G TG++SC RF +N IV+ S D + +W++ + T GH G V +++++PD Sbjct: 140 GHTGYLSCCRFLDDN---QIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTR 196 Query: 191 LCASGGKDGVTLLWDLTEGK-RLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLES 364 L SG D LWD+ EG R S IN++CF PN + D + +++DL + Sbjct: 197 LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA 256 Query: 365 KHIVQDLRPEVPVSSKQMLYC--TCLSWSADGSTLYAGYTDGTIRIY 499 E+ S + C T +S+S G L AGY D ++ Sbjct: 257 DQ-------ELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVW 296 Score = 53.5 bits (127), Expect = 4e-07 Identities = 45/167 (26%), Positives = 75/167 (44%), Gaps = 4/167 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G TG V + +P+ VSG+ D S K+W++ R T GH ++A+ P+G+ Sbjct: 181 GHTGDVMSLSLAPDT--RLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGN 238 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSI---INSLCFSPNRYWLCAATQD-SIKIWDL 358 A+G D L+DL + L + +I I S+ FS + L A D + +WD Sbjct: 239 AFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWD- 297 Query: 359 ESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 ++ R V + +CL + DG + G D ++I+ Sbjct: 298 ----ALKADRAGVLAGHDNRV--SCLGVTDDGMAVATGSWDSFLKIW 338 Score = 33.1 bits (74), Expect = 0.55 Identities = 19/84 (22%), Positives = 41/84 (48%), Gaps = 2/84 (2%) Frame = +2 Query: 122 KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLD-AGSIINSLCF 298 + R TL GH + A+ D L S +DG ++WD +++++ S + + + Sbjct: 45 RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAY 104 Query: 299 SPN-RYWLCAATQDSIKIWDLESK 367 +P+ Y C + I++L+++ Sbjct: 105 APSGNYVACGGLDNICSIYNLKTR 128 Score = 32.7 bits (73), Expect = 0.72 Identities = 16/56 (28%), Positives = 26/56 (46%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWD 235 +++G D + VW+ L GH VS + V+ DG A+G D +W+ Sbjct: 284 LLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 339
>GBB1_BRARE (Q6PH57) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 340 Score = 74.3 bits (181), Expect = 2e-13 Identities = 52/167 (31%), Positives = 82/167 (49%), Gaps = 4/167 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G TG++SC RF +N IV+ S D + +W++ + T GH G V +++++PD Sbjct: 141 GHTGYLSCCRFLDDN---QIVTSSGDTTCALWDIETGQQTTTFAGHTGDVMSLSLAPDTR 197 Query: 191 LCASGGKDGVTLLWDLTEGK-RLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLES 364 L SG D LWD+ EG R S IN++CF PN + D + +++DL + Sbjct: 198 LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA 257 Query: 365 KHIVQDLRPEVPVSSKQMLYC--TCLSWSADGSTLYAGYTDGTIRIY 499 E+ V S + C T +++S G L AGY D ++ Sbjct: 258 DQ-------ELMVYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVW 297 Score = 52.8 bits (125), Expect = 7e-07 Identities = 45/167 (26%), Positives = 74/167 (44%), Gaps = 4/167 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G TG V + +P+ VSG+ D S K+W++ R T GH ++A+ P+G+ Sbjct: 182 GHTGDVMSLSLAPDT--RLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGN 239 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSI---INSLCFSPNRYWLCAATQD-SIKIWDL 358 A+G D L+DL + L +I I S+ FS + L A D + +WD Sbjct: 240 AFATGSDDATCRLFDLRADQELMVYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWD- 298 Query: 359 ESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 ++ R V + +CL + DG + G D ++I+ Sbjct: 299 ----ALKADRAGVLAGHDNRV--SCLGVTDDGMAVATGSWDSFLKIW 339 Score = 33.1 bits (74), Expect = 0.55 Identities = 19/84 (22%), Positives = 41/84 (48%), Gaps = 2/84 (2%) Frame = +2 Query: 122 KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLD-AGSIINSLCF 298 + R TL GH + A+ D L S +DG ++WD +++++ S + + + Sbjct: 46 RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAY 105 Query: 299 SPN-RYWLCAATQDSIKIWDLESK 367 +P+ Y C + I++L+++ Sbjct: 106 APSGNYVACGGLDNICSIYNLKTR 129 Score = 32.7 bits (73), Expect = 0.72 Identities = 16/56 (28%), Positives = 26/56 (46%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWD 235 +++G D + VW+ L GH VS + V+ DG A+G D +W+ Sbjct: 285 LLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>NLE1_PONPY (Q5RFF8) Notchless homolog 1| Length = 484 Score = 73.9 bits (180), Expect = 3e-13 Identities = 55/175 (31%), Positives = 83/175 (47%), Gaps = 8/175 (4%) Frame = +2 Query: 2 SARGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSP 181 S G + V V FSP + SGS D +V+ W+L+ T GH +V +++ SP Sbjct: 108 SLEGHSEAVISVAFSPTG--KYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSP 165 Query: 182 DGSLCASGGKDGVTLLWDLTEGKRLYSLDAG--SIINSLCFSP------NRYWLCAATQD 337 DG ASG K+G LLWD + GK++ AG I L + P RY ++ Sbjct: 166 DGKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDG 225 Query: 338 SIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYK 502 S++IWD + + + + TCL W DG LY+ D TI++++ Sbjct: 226 SVRIWDTTAGRCER-------ILTGHTQSVTCLRWGGDG-LLYSASQDRTIKVWR 272 Score = 63.9 bits (154), Expect = 3e-10 Identities = 56/210 (26%), Positives = 90/210 (42%), Gaps = 45/210 (21%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPD-- 184 G T V+C+R+ + + S S DR++KVW + L TL GHG +V+ +A+S D Sbjct: 243 GHTQSVTCLRWGGDGL---LYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMALSTDYA 299 Query: 185 -------------------GSL---------------------CASGGKDGVTLLWDLTE 244 GSL SG D LW E Sbjct: 300 LRTGAFEPAEASVNPQDLQGSLQELKERALSRYNLMRGQGPERLVSGSDDFTLFLWSPAE 359 Query: 245 GKRLYSLDAG--SIINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQDLRPEVPVSSKQ 415 K+ + G ++IN + FSP+ + +A+ D SIK+WD + + LR V + Sbjct: 360 DKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQ- 418 Query: 416 MLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 ++WSAD L +G +D T++++ + Sbjct: 419 ------IAWSADSRLLVSGSSDSTLKVWDV 442 Score = 60.1 bits (144), Expect = 4e-09 Identities = 43/148 (29%), Positives = 75/148 (50%), Gaps = 3/148 (2%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCT-LDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTE 244 +VSGS D ++ +W+ K T + GH ++ V SPD + AS D LWD Sbjct: 343 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 402 Query: 245 GKRLYSLDAG-SIINSLCFSPNRYWLCAATQDS-IKIWDLESKHIVQDLRPEVPVSSKQM 418 GK L SL + + + +S + L + + DS +K+WD++++ + DL P + ++ Sbjct: 403 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDL----PGHADEV 458 Query: 419 LYCTCLSWSADGSTLYAGYTDGTIRIYK 502 + WS DG + +G D +RI++ Sbjct: 459 Y---AVDWSPDGQRVASGGKDKCLRIWR 483 Score = 47.8 bits (112), Expect = 2e-05 Identities = 32/116 (27%), Positives = 56/116 (48%), Gaps = 2/116 (1%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G ++ V FSP++ + S S+D+S+K+W+ K +L GH V +A S D Sbjct: 369 GHQALINQVLFSPDS--RIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSR 426 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQDS-IKIW 352 L SG D +WD+ K L + ++ +SP+ + + +D ++IW Sbjct: 427 LLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 482
>NLE1_HUMAN (Q9NVX2) Notchless homolog 1| Length = 484 Score = 73.9 bits (180), Expect = 3e-13 Identities = 55/175 (31%), Positives = 83/175 (47%), Gaps = 8/175 (4%) Frame = +2 Query: 2 SARGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSP 181 S G + V V FSP + SGS D +V+ W+L+ T GH +V +++ SP Sbjct: 108 SLEGHSEAVISVAFSPTG--KYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSP 165 Query: 182 DGSLCASGGKDGVTLLWDLTEGKRLYSLDAG--SIINSLCFSP------NRYWLCAATQD 337 DG ASG K+G LLWD + GK++ AG I L + P RY ++ Sbjct: 166 DGKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDG 225 Query: 338 SIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYK 502 S++IWD + + + + TCL W DG LY+ D TI++++ Sbjct: 226 SVRIWDTTAGRCER-------ILTGHTQSVTCLRWGGDG-LLYSASQDRTIKVWR 272 Score = 63.9 bits (154), Expect = 3e-10 Identities = 56/210 (26%), Positives = 90/210 (42%), Gaps = 45/210 (21%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPD-- 184 G T V+C+R+ + + S S DR++KVW + L TL GHG +V+ +A+S D Sbjct: 243 GHTQSVTCLRWGGDGL---LYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMALSTDYA 299 Query: 185 -------------------GSL---------------------CASGGKDGVTLLWDLTE 244 GSL SG D LW E Sbjct: 300 LRTGAFEPAEASVNPQDLQGSLQELKERALSRYNLVRGQGPERLVSGSDDFTLFLWSPAE 359 Query: 245 GKRLYSLDAG--SIINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQDLRPEVPVSSKQ 415 K+ + G ++IN + FSP+ + +A+ D SIK+WD + + LR V + Sbjct: 360 DKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQ- 418 Query: 416 MLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 ++WSAD L +G +D T++++ + Sbjct: 419 ------IAWSADSRLLVSGSSDSTLKVWDV 442 Score = 60.1 bits (144), Expect = 4e-09 Identities = 43/148 (29%), Positives = 75/148 (50%), Gaps = 3/148 (2%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCT-LDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTE 244 +VSGS D ++ +W+ K T + GH ++ V SPD + AS D LWD Sbjct: 343 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 402 Query: 245 GKRLYSLDAG-SIINSLCFSPNRYWLCAATQDS-IKIWDLESKHIVQDLRPEVPVSSKQM 418 GK L SL + + + +S + L + + DS +K+WD++++ + DL P + ++ Sbjct: 403 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDL----PGHADEV 458 Query: 419 LYCTCLSWSADGSTLYAGYTDGTIRIYK 502 + WS DG + +G D +RI++ Sbjct: 459 Y---AVDWSPDGQRVASGGKDKCLRIWR 483 Score = 47.8 bits (112), Expect = 2e-05 Identities = 32/116 (27%), Positives = 56/116 (48%), Gaps = 2/116 (1%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G ++ V FSP++ + S S+D+S+K+W+ K +L GH V +A S D Sbjct: 369 GHQALINQVLFSPDS--RIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSR 426 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQDS-IKIW 352 L SG D +WD+ K L + ++ +SP+ + + +D ++IW Sbjct: 427 LLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 482
>Y1491_SYNY3 (P74598) Hypothetical WD-repeat protein sll1491| Length = 348 Score = 73.9 bits (180), Expect = 3e-13 Identities = 51/171 (29%), Positives = 89/171 (52%), Gaps = 2/171 (1%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 GPT + V F+P+ + DR++K W+ +L T G+++ +AV+PDG Sbjct: 188 GPT---TSVVFTPDGSQFITGAIGQDRTIKFWDANTFELLGTSPQQPGFINGLAVTPDGR 244 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSI-INSLCFSPNRYWLCAATQD-SIKIWDLES 364 ++ V W+L + K L+S+ S+ IN++ SPN W+ A ++ +I I+DL + Sbjct: 245 KLVGAVRNFVKA-WNLADAKELFSVRGPSLEINTIAVSPNNRWVATANKEGTIMIFDLAN 303 Query: 365 KHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISGFS 517 V LR + L++S DG+TLY+G D T++I+ +S + Sbjct: 304 GKQVTTLRGHQG-------WVLSLAFSPDGNTLYSGAEDKTVKIWDLSALA 347 Score = 55.8 bits (133), Expect = 8e-08 Identities = 28/80 (35%), Positives = 48/80 (60%) Frame = +2 Query: 2 SARGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSP 181 S RGP+ ++ + SPNN + + + + ++ +++L N K TL GH G+V ++A SP Sbjct: 267 SVRGPSLEINTIAVSPNN--RWVATANKEGTIMIFDLANGKQVTTLRGHQGWVLSLAFSP 324 Query: 182 DGSLCASGGKDGVTLLWDLT 241 DG+ SG +D +WDL+ Sbjct: 325 DGNTLYSGAEDKTVKIWDLS 344 Score = 42.4 bits (98), Expect = 0.001 Identities = 39/114 (34%), Positives = 53/114 (46%), Gaps = 12/114 (10%) Frame = +2 Query: 50 NNFAPTIVS--GSW-----DRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCAS-G 205 NNFA +S G W D +V V + + TL GH VS VA SPDG S Sbjct: 104 NNFADLAISADGQWLAIAADNNVDVRRVRDGMRVETLVGHTDKVSGVAFSPDGETIVSVS 163 Query: 206 GKDGVTLLWDLTEGKRLYSL-DAGSIINSLCFSP--NRYWLCAATQD-SIKIWD 355 G D +W+ G + +L D S+ F+P +++ A QD +IK WD Sbjct: 164 GGDRTIRIWERASGNLIQTLADNLGPTTSVVFTPDGSQFITGAIGQDRTIKFWD 217 Score = 36.6 bits (83), Expect = 0.050 Identities = 33/126 (26%), Positives = 59/126 (46%), Gaps = 4/126 (3%) Frame = +2 Query: 137 LDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLDAGSIINS---LCFSPN 307 L G G ++A+ ++PDG A D L DL + +YS S +N+ L S + Sbjct: 57 LSGFQGIITALNITPDGKYLAVATADNQITLIDLANQEVVYS--QRSPVNNFADLAISAD 114 Query: 308 RYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYA-GYTDG 484 WL A +++ + + + +R E V + + +++S DG T+ + D Sbjct: 115 GQWLAIAADNNVDV-----RRVRDGMRVETLVGHTDKV--SGVAFSPDGETIVSVSGGDR 167 Query: 485 TIRIYK 502 TIRI++ Sbjct: 168 TIRIWE 173
>NLE1_BOVIN (Q58D20) Notchless homolog 1| Length = 485 Score = 73.6 bits (179), Expect = 4e-13 Identities = 54/175 (30%), Positives = 83/175 (47%), Gaps = 8/175 (4%) Frame = +2 Query: 2 SARGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSP 181 S G + V V FSP + SGS D +V+ W+L+ T GH +V +++ SP Sbjct: 109 SLEGHSEAVISVAFSPTG--KYLASGSGDTTVRFWDLSTETPHFTCQGHRHWVLSISWSP 166 Query: 182 DGSLCASGGKDGVTLLWDLTEGKRLYSLDAG--SIINSLCFSP------NRYWLCAATQD 337 DG ASG K+G LLWD + GK++ G I +L + P RY ++ Sbjct: 167 DGKKLASGCKNGQILLWDPSTGKQVGRALTGHSKWITALSWEPLHANPECRYVASSSKDG 226 Query: 338 SIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYK 502 S+++WD + + L + TCL W DG LY+ D TI++++ Sbjct: 227 SVRVWDTTAGRCERTL-------TGHAQSVTCLRWGGDG-LLYSASQDRTIKVWR 273 Score = 63.2 bits (152), Expect = 5e-10 Identities = 55/212 (25%), Positives = 90/212 (42%), Gaps = 45/212 (21%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPD------- 184 V+C+R+ + + S S DR++KVW + L TL GHG +V+ +A+S D Sbjct: 249 VTCLRWGGDGL---LYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMALSTDYALRTGA 305 Query: 185 --------------GSL---------------------CASGGKDGVTLLWDLTEGKRLY 259 GSL SG D LW E K+ Sbjct: 306 FEPAEASVNAQDLRGSLQELKERALSRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPL 365 Query: 260 SLDAG--SIINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQDLRPEVPVSSKQMLYCT 430 + G ++IN + FSP+ + +A+ D SIK+WD + + LR V + Sbjct: 366 ARMTGHQALINQVVFSPDSRVIASASFDKSIKLWDGRTGKYLASLRGHVAAVYQ------ 419 Query: 431 CLSWSADGSTLYAGYTDGTIRIYKISGFSYSS 526 ++WSAD L +G +D T++++ + S+ Sbjct: 420 -IAWSADSRLLVSGSSDSTLKVWDVKAQKLST 450 Score = 57.4 bits (137), Expect = 3e-08 Identities = 42/148 (28%), Positives = 75/148 (50%), Gaps = 3/148 (2%) Frame = +2 Query: 68 IVSGSWDRSVKVWN-LTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTE 244 +VSGS D ++ +W+ + K + GH ++ V SPD + AS D LWD Sbjct: 344 LVSGSDDFTLFLWSPAEDKKPLARMTGHQALINQVVFSPDSRVIASASFDKSIKLWDGRT 403 Query: 245 GKRLYSLDAG-SIINSLCFSPNRYWLCAATQDS-IKIWDLESKHIVQDLRPEVPVSSKQM 418 GK L SL + + + +S + L + + DS +K+WD+++ Q L ++P + ++ Sbjct: 404 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKA----QKLSTDLPGHADEV 459 Query: 419 LYCTCLSWSADGSTLYAGYTDGTIRIYK 502 + WS DG + +G D +RI++ Sbjct: 460 Y---AVDWSPDGQRVASGGKDKCLRIWR 484 Score = 47.4 bits (111), Expect = 3e-05 Identities = 33/116 (28%), Positives = 56/116 (48%), Gaps = 2/116 (1%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G ++ V FSP++ I S S+D+S+K+W+ K +L GH V +A S D Sbjct: 370 GHQALINQVVFSPDS--RVIASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSR 427 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQDS-IKIW 352 L SG D +WD+ K L + ++ +SP+ + + +D ++IW Sbjct: 428 LLVSGSSDSTLKVWDVKAQKLSTDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 483
>GBB1_CRIGR (Q6TMK6) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 73.6 bits (179), Expect = 4e-13 Identities = 52/167 (31%), Positives = 81/167 (48%), Gaps = 4/167 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G TG++SC RF +N IV+ S D + +W++ + T GH G V +++++PD Sbjct: 140 GHTGYLSCCRFLNDN---QIVTSSEDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTR 196 Query: 191 LCASGGKDGVTLLWDLTEGK-RLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLES 364 L SG D LWD+ EG R S IN++CF PN + D + +++DL + Sbjct: 197 LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA 256 Query: 365 KHIVQDLRPEVPVSSKQMLYC--TCLSWSADGSTLYAGYTDGTIRIY 499 E+ S + C T +S+S G L AGY D ++ Sbjct: 257 DQ-------ELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVW 296 Score = 53.5 bits (127), Expect = 4e-07 Identities = 45/167 (26%), Positives = 75/167 (44%), Gaps = 4/167 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G TG V + +P+ VSG+ D S K+W++ R T GH ++A+ P+G+ Sbjct: 181 GHTGDVMSLSLAPDT--RLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGN 238 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSI---INSLCFSPNRYWLCAATQD-SIKIWDL 358 A+G D L+DL + L + +I I S+ FS + L A D + +WD Sbjct: 239 AFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWD- 297 Query: 359 ESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 ++ R V + +CL + DG + G D ++I+ Sbjct: 298 ----ALKADRAGVLAGHDNRV--SCLGVTDDGMAVATGSWDSFLKIW 338 Score = 33.1 bits (74), Expect = 0.55 Identities = 19/84 (22%), Positives = 41/84 (48%), Gaps = 2/84 (2%) Frame = +2 Query: 122 KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLD-AGSIINSLCF 298 + R TL GH + A+ D L S +DG ++WD +++++ S + + + Sbjct: 45 RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAY 104 Query: 299 SPN-RYWLCAATQDSIKIWDLESK 367 +P+ Y C + I++L+++ Sbjct: 105 APSGNYVACGGLDNICSIYNLKTR 128 Score = 32.7 bits (73), Expect = 0.72 Identities = 16/56 (28%), Positives = 26/56 (46%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWD 235 +++G D + VW+ L GH VS + V+ DG A+G D +W+ Sbjct: 284 LLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 339
>GBB1_XENLA (P79959) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) (XGbeta1) Length = 340 Score = 73.2 bits (178), Expect = 5e-13 Identities = 50/167 (29%), Positives = 81/167 (48%), Gaps = 4/167 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G TG++SC RF +N I++ S D + +W++ + T GH G V +++++PD Sbjct: 141 GHTGYLSCCRFLDDN---QIITSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDSR 197 Query: 191 LCASGGKDGVTLLWDLTEGK-RLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLES 364 SG D LWD+ EG R S IN++CF PN + D + +++DL + Sbjct: 198 CFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA 257 Query: 365 KHIVQDLRPEVPVSSKQMLYC--TCLSWSADGSTLYAGYTDGTIRIY 499 E+ V S + C T +++S G L AGY D ++ Sbjct: 258 DQ-------ELMVYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVW 297 Score = 53.1 bits (126), Expect = 5e-07 Identities = 45/167 (26%), Positives = 75/167 (44%), Gaps = 4/167 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G TG V + +P++ VSG+ D S K+W++ R T GH ++A+ P+G+ Sbjct: 182 GHTGDVMSLSLAPDSRC--FVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGN 239 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSI---INSLCFSPNRYWLCAATQD-SIKIWDL 358 A+G D L+DL + L +I I S+ FS + L A D + +WD Sbjct: 240 AFATGSDDATCRLFDLRADQELMVYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWD- 298 Query: 359 ESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 ++ R V + +CL + DG + G D ++I+ Sbjct: 299 ----TLKADRAGVLAGHDNRV--SCLGVTDDGMAVATGSWDSFLKIW 339 Score = 32.7 bits (73), Expect = 0.72 Identities = 16/56 (28%), Positives = 26/56 (46%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWD 235 +++G D + VW+ L GH VS + V+ DG A+G D +W+ Sbjct: 285 LLAGYDDFNCNVWDTLKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340 Score = 32.7 bits (73), Expect = 0.72 Identities = 19/84 (22%), Positives = 41/84 (48%), Gaps = 2/84 (2%) Frame = +2 Query: 122 KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLD-AGSIINSLCF 298 + R TL GH + A+ D L S +DG ++WD +++++ S + + + Sbjct: 46 RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAY 105 Query: 299 SPN-RYWLCAATQDSIKIWDLESK 367 +P+ Y C + I++L+++ Sbjct: 106 APSGNYVACGGLDNICPIYNLKTR 129
>TUP11_SCHPO (Q09715) Transcriptional repressor tup11| Length = 614 Score = 72.0 bits (175), Expect = 1e-12 Identities = 44/162 (27%), Positives = 86/162 (53%), Gaps = 1/162 (0%) Frame = +2 Query: 23 WVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCAS 202 +V + FSP+ +V+G+ DR +K+W+L+ K+R GH + ++ S +G S Sbjct: 362 YVRTIAFSPDG--KYLVTGTEDRQIKLWDLSTQKVRYVFSGHEQDIYSLDFSHNGRFIVS 419 Query: 203 GGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDS-IKIWDLESKHIVQ 379 G D LWD+ G+ + L+ + + ++ SPN ++ + D I++W + S +V+ Sbjct: 420 GSGDRTARLWDVETGQCILKLEIENGVTAIAISPNDQFIAVGSLDQIIRVWSV-SGTLVE 478 Query: 380 DLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 L K+ +Y +++S D S L +G D TI+++++ Sbjct: 479 RLE-----GHKESVY--SIAFSPDSSILLSGSLDKTIKVWEL 513 Score = 57.8 bits (138), Expect = 2e-08 Identities = 40/127 (31%), Positives = 62/127 (48%), Gaps = 15/127 (11%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCK------------LRCTLDGHGGYVSAV 169 V + FSP++ ++SGS D+++KVW L + + T GH +V +V Sbjct: 487 VYSIAFSPDS--SILLSGSLDKTIKVWELQATRSVGLSAIKPEGICKATYTGHTDFVLSV 544 Query: 170 AVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLDA--GSIINSLCFSPNRYWLCAATQD-S 340 AVSPD SG KD WDL G+ + S+I S+CFSP+ + + D Sbjct: 545 AVSPDSRWGLSGSKDRSMQFWDLQTGQSYLTCQGHKNSVI-SVCFSPDGRQFASGSGDLR 603 Query: 341 IKIWDLE 361 +IW ++ Sbjct: 604 ARIWSID 610 Score = 43.9 bits (102), Expect = 3e-04 Identities = 28/76 (36%), Positives = 39/76 (51%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G T +V V SP++ +SGS DRS++ W+L + T GH V +V SPDG Sbjct: 536 GHTDFVLSVAVSPDSRWG--LSGSKDRSMQFWDLQTGQSYLTCQGHKNSVISVCFSPDGR 593 Query: 191 LCASGGKDGVTLLWDL 238 ASG D +W + Sbjct: 594 QFASGSGDLRARIWSI 609
>GBB4_HUMAN (Q9HAV0) Guanine nucleotide-binding protein beta subunit 4| (Transducin beta chain 4) Length = 339 Score = 71.6 bits (174), Expect = 1e-12 Identities = 49/167 (29%), Positives = 82/167 (49%), Gaps = 4/167 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G TG++SC RF ++ IV+ S D + +W++ + T GH G V ++++SPD Sbjct: 140 GHTGYLSCCRFLDDS---QIVTSSGDTTCALWDIETAQQTTTFTGHSGDVMSLSLSPDMR 196 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAG-SIINSLCFSPNRYWLCAATQD-SIKIWDLES 364 SG D + LWD+ +G S S IN++ F PN Y + D + +++DL + Sbjct: 197 TFVSGACDASSKLWDIRDGMCRQSFTGHVSDINAVSFFPNGYAFATGSDDATCRLFDLRA 256 Query: 365 KHIVQDLRPEVPVSSKQMLYC--TCLSWSADGSTLYAGYTDGTIRIY 499 E+ + S + C T +++S G L AGY D ++ Sbjct: 257 DQ-------ELLLYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVW 296 Score = 35.0 bits (79), Expect = 0.14 Identities = 28/130 (21%), Positives = 57/130 (43%), Gaps = 2/130 (1%) Frame = +2 Query: 122 KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLD-AGSIINSLCF 298 + R TL GH + A+ D L S +DG ++WD +++++ S + + + Sbjct: 45 RTRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAY 104 Query: 299 SPN-RYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGY 475 +P+ Y C + I++L+++ + E+P + + C L D S + Sbjct: 105 APSGNYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFL----DDSQIVTSS 160 Query: 476 TDGTIRIYKI 505 D T ++ I Sbjct: 161 GDTTCALWDI 170 Score = 31.6 bits (70), Expect = 1.6 Identities = 16/56 (28%), Positives = 26/56 (46%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWD 235 +++G D + VW+ L GH VS + V+ DG A+G D +W+ Sbjct: 284 LLAGYDDFNCNVWDTLKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN 339 Score = 30.0 bits (66), Expect = 4.6 Identities = 35/151 (23%), Positives = 61/151 (40%), Gaps = 5/151 (3%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL--T 241 +VS S D + +W+ + +V A +P G+ A GG D + +++L Sbjct: 69 LVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTR 128 Query: 242 EGKRLYS--LDAGSIINSLC-FSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSK 412 EG S L + S C F + + ++ + +WD+E+ Q S Sbjct: 129 EGNVRVSRELPGHTGYLSCCRFLDDSQIVTSSGDTTCALWDIET---AQQTTTFTGHSGD 185 Query: 413 QMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 M LS S D T +G D + +++ I Sbjct: 186 VM----SLSLSPDMRTFVSGACDASSKLWDI 212
>WD51A_BOVIN (Q2TBP4) WD-repeat protein 51A| Length = 407 Score = 71.6 bits (174), Expect = 1e-12 Identities = 49/163 (30%), Positives = 84/163 (51%), Gaps = 3/163 (1%) Frame = +2 Query: 23 WVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCAS 202 WV C +FSP+ IVS S D++VK+W+ T+ + + HGG+V+ V P G+ A+ Sbjct: 147 WVRCAKFSPDG--RLIVSASDDKTVKLWDKTSRECVHSYCEHGGFVTYVDFHPSGTCIAA 204 Query: 203 GGKDGVTLLWDLTEGKRL--YSLDAGSIINSLCFSPNRYWLCAATQDS-IKIWDLESKHI 373 G D +WD+ + L Y L + + +N+L F P+ +L A+ DS +KI DL + Sbjct: 205 AGMDNTVKVWDVRTHRLLQHYQLHSAA-VNALSFHPSGNYLVTASSDSTLKILDLMEGRL 263 Query: 374 VQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYK 502 + L + T +++S G +G +D + ++K Sbjct: 264 LYTLHGHQGPA-------TTVAFSRTGEYFASGGSDEQVMVWK 299 Score = 62.8 bits (151), Expect = 6e-10 Identities = 45/165 (27%), Positives = 74/165 (44%), Gaps = 2/165 (1%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG 187 R T V V F + + V+ S D++VKVW+ K +L H +V SPDG Sbjct: 100 RAHTATVRSVHFCSDG--QSFVTASDDKTVKVWSTHRQKFLFSLSQHINWVRCAKFSPDG 157 Query: 188 SLCASGGKDGVTLLWDLTEGKRLYS-LDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLE 361 L S D LWD T + ++S + G + + F P+ + AA D ++K+WD+ Sbjct: 158 RLIVSASDDKTVKLWDKTSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVR 217 Query: 362 SKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRI 496 + ++Q + LS+ G+ L +D T++I Sbjct: 218 THRLLQHYQ-------LHSAAVNALSFHPSGNYLVTASSDSTLKI 255 Score = 52.0 bits (123), Expect = 1e-06 Identities = 40/166 (24%), Positives = 73/166 (43%), Gaps = 2/166 (1%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG 187 +G V+ V FS N + SGS D + VW++ GH V+ V SP G Sbjct: 16 KGHRDAVTSVDFSLNT--KQLASGSMDSCLMVWHMKPQTRAYRFAGHKDAVTCVNFSPSG 73 Query: 188 SLCASGGKDGVTLLW-DLTEGKRLYSLDAGSIINSLCF-SPNRYWLCAATQDSIKIWDLE 361 L ASG +D +W +G+ + + S+ F S + ++ A+ ++K+W Sbjct: 74 HLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWSTH 133 Query: 362 SKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 + + L S+ + + C +S DG + + D T++++ Sbjct: 134 RQKFLFSL-------SQHINWVRCAKFSPDGRLIVSASDDKTVKLW 172
>WD51A_MOUSE (Q8JZX3) WD-repeat protein 51A| Length = 405 Score = 70.9 bits (172), Expect = 2e-12 Identities = 49/163 (30%), Positives = 83/163 (50%), Gaps = 3/163 (1%) Frame = +2 Query: 23 WVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCAS 202 WV C +FSP+ IVS S D++VK+W+ T+ + + HGG+V+ V P G+ A+ Sbjct: 147 WVRCAKFSPDG--RLIVSASDDKTVKLWDKTSRECIHSYCEHGGFVTYVDFHPSGTCIAA 204 Query: 203 GGKDGVTLLWDLTEGKRL--YSLDAGSIINSLCFSPNRYWLCAATQDS-IKIWDLESKHI 373 G D +WD + L Y L + + +N+L F P+ +L A+ DS +KI DL + Sbjct: 205 AGMDNTVKVWDARTHRLLQHYQLHSAA-VNALSFHPSGNYLITASSDSTLKILDLMEGRL 263 Query: 374 VQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYK 502 + L + T +++S G +G +D + ++K Sbjct: 264 LYTLHGHQGPA-------TTVAFSRTGEYFASGGSDEQVMVWK 299 Score = 61.6 bits (148), Expect = 1e-09 Identities = 44/165 (26%), Positives = 74/165 (44%), Gaps = 2/165 (1%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG 187 R T V V F + ++V+ S D++VKVW+ + +L H +V SPDG Sbjct: 100 RAHTATVRSVHFCSDG--QSLVTASDDKTVKVWSTHRQRFLFSLTQHINWVRCAKFSPDG 157 Query: 188 SLCASGGKDGVTLLWDLTEGKRLYS-LDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLE 361 L S D LWD T + ++S + G + + F P+ + AA D ++K+WD Sbjct: 158 RLIVSASDDKTVKLWDKTSRECIHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDAR 217 Query: 362 SKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRI 496 + ++Q + LS+ G+ L +D T++I Sbjct: 218 THRLLQHYQ-------LHSAAVNALSFHPSGNYLITASSDSTLKI 255 Score = 56.2 bits (134), Expect = 6e-08 Identities = 40/166 (24%), Positives = 74/166 (44%), Gaps = 2/166 (1%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG 187 +G V+CV FS N + SGS D ++ +W++ GH V+ V SP G Sbjct: 16 KGHRDAVTCVDFSLNT--KHLASGSMDSTLMIWHMKPQSRAYRFTGHKDAVTCVNFSPSG 73 Query: 188 SLCASGGKDGVTLLW-DLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLE 361 L ASG +D +W +G+ + + S+ F + L A+ D ++K+W Sbjct: 74 HLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVWSTH 133 Query: 362 SKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 + + L ++ + + C +S DG + + D T++++ Sbjct: 134 RQRFLFSL-------TQHINWVRCAKFSPDGRLIVSASDDKTVKLW 172
>WD51B_MOUSE (Q8BHD1) WD-repeat protein 51B| Length = 476 Score = 70.5 bits (171), Expect = 3e-12 Identities = 50/165 (30%), Positives = 80/165 (48%), Gaps = 3/165 (1%) Frame = +2 Query: 17 TGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLC 196 T WV C +FSP+ IVS S D+++K+W+ TN + G+ + V +P+G+ Sbjct: 144 THWVRCAKFSPDG--RLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPNGTCI 201 Query: 197 ASGGKDGVTLLWDLTEGKRLYSLDAGSI-INSLCFSPNRYWLCAATQD-SIKIWDLESKH 370 AS G D +WD+ K L S +N L F P L A+ D ++K+ DL Sbjct: 202 ASAGSDHAVKIWDIRMNKLLQHYQVHSCGVNCLSFHPLGNSLVTASSDGTVKMLDLIEGR 261 Query: 371 IVQDLRPEV-PVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYK 502 ++ L+ PV + +S+S DG L +G D + I++ Sbjct: 262 LIYTLQGHTGPVFT--------VSFSKDGELLTSGGADAQVLIWR 298 Score = 65.1 bits (157), Expect = 1e-10 Identities = 42/147 (28%), Positives = 74/147 (50%), Gaps = 4/147 (2%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 +V+ S D+S+KVW++ + +L H +V SPDG L S +D +WD T Sbjct: 117 LVTASEDKSIKVWSMFRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNK 176 Query: 248 KRLYSL-DAGSIINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQDLRPEVPVSSKQML 421 + + + D+ N + F+PN + +A D ++KIWD+ ++Q Q+ Sbjct: 177 QCVNNFSDSVGFANFVDFNPNGTCIASAGSDHAVKIWDIRMNKLLQHY---------QVH 227 Query: 422 YC--TCLSWSADGSTLYAGYTDGTIRI 496 C CLS+ G++L +DGT+++ Sbjct: 228 SCGVNCLSFHPLGNSLVTASSDGTVKM 254 Score = 59.7 bits (143), Expect = 5e-09 Identities = 46/168 (27%), Positives = 76/168 (45%), Gaps = 2/168 (1%) Frame = +2 Query: 2 SARGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSP 181 S +G ++ FSPN I + SWD + +W+L GH V+++ SP Sbjct: 13 SFKGHKAAITSADFSPN--CKQIATASWDTFLMLWSLKPHARAYRYVGHKDVVTSLQFSP 70 Query: 182 DGSLCASGGKDGVTLLWDL-TEGKRLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWD 355 G+L AS +D LW L +GK + + S+ FS + L A++D SIK+W Sbjct: 71 QGNLLASASRDRTVRLWVLDRKGKSSEFKAHTAPVRSVDFSADGQLLVTASEDKSIKVWS 130 Query: 356 LESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 + + + L + + C +S DG + + D TI+I+ Sbjct: 131 MFRQRFLYSL-------YRHTHWVRCAKFSPDGRLIVSCSEDKTIKIW 171 Score = 52.8 bits (125), Expect = 7e-07 Identities = 40/162 (24%), Positives = 76/162 (46%), Gaps = 2/162 (1%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 V+ ++FSP + S S DR+V++W L H V +V S DG L + Sbjct: 63 VTSLQFSPQG--NLLASASRDRTVRLWVLDRKGKSSEFKAHTAPVRSVDFSADGQLLVTA 120 Query: 206 GKDGVTLLWDLTEGKRLYSLDAGS-IINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQ 379 +D +W + + LYSL + + FSP+ + + ++D +IKIWD +K V Sbjct: 121 SEDKSIKVWSMFRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVN 180 Query: 380 DLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 + S + + + ++ +G+ + + +D ++I+ I Sbjct: 181 NF-------SDSVGFANFVDFNPNGTCIASAGSDHAVKIWDI 215 Score = 44.3 bits (103), Expect = 2e-04 Identities = 33/130 (25%), Positives = 60/130 (46%), Gaps = 3/130 (2%) Frame = +2 Query: 125 LRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYS-LDAGSIINSLCFS 301 L + GH +++ SP+ A+ D +LW L R Y + ++ SL FS Sbjct: 10 LERSFKGHKAAITSADFSPNCKQIATASWDTFLMLWSLKPHARAYRYVGHKDVVTSLQFS 69 Query: 302 PNRYWLCAATQD-SIKIWDLESKHIVQDLRPE-VPVSSKQMLYCTCLSWSADGSTLYAGY 475 P L +A++D ++++W L+ K + + PV S + +SADG L Sbjct: 70 PQGNLLASASRDRTVRLWVLDRKGKSSEFKAHTAPVRS--------VDFSADGQLLVTAS 121 Query: 476 TDGTIRIYKI 505 D +I+++ + Sbjct: 122 EDKSIKVWSM 131
>WDR57_MOUSE (Q6PE01) WD-repeat protein 57| Length = 358 Score = 70.5 bits (171), Expect = 3e-12 Identities = 54/207 (26%), Positives = 88/207 (42%), Gaps = 38/207 (18%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLT-NCKLRCTLDGHGGYVSAVAVSPDG 187 G G V C +F PN T+ S +DR + +WN+ +C TL GH G V + + DG Sbjct: 65 GHEGEVYCCKFHPNG--STLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDG 122 Query: 188 SLCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNR--YWLCAATQD-SIKIWDL 358 S+ S D +WD G+R+ L + + C+ R +C + D ++K+WD+ Sbjct: 123 SMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDI 182 Query: 359 ESKHIVQDLRPEVPV-------SSKQML---------------------------YCTCL 436 K VQ + V +S Q++ T L Sbjct: 183 RKKAAVQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGL 242 Query: 437 SWSADGSTLYAGYTDGTIRIYKISGFS 517 S S++GS L + D T+R++ + F+ Sbjct: 243 SLSSEGSYLLSNAMDNTVRVWDVRPFA 269 Score = 55.5 bits (132), Expect = 1e-07 Identities = 49/172 (28%), Positives = 78/172 (45%), Gaps = 8/172 (4%) Frame = +2 Query: 8 RGPTGWV-SCVRFSPNNFAPTIV-SGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSP 181 +G T +V SC P P +V +GS D +VK+W++ K + V AV + Sbjct: 149 KGHTSFVNSCY---PARRGPQLVCTGSDDGTVKLWDIRK-KAAVQTFQNTYQVLAVTFND 204 Query: 182 DGSLCASGGKDGVTLLWDLTEGKRLYSL--DAGSIINSLCFSPNRYWLCAATQDSIKIWD 355 SGG D +WDL + K Y++ A S+ S Y L A +++++WD Sbjct: 205 TSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWD 264 Query: 356 LE----SKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 + + V+ + V K +L C SWS DGS + AG D + ++ Sbjct: 265 VRPFAPKERCVKIFQGNVHNFEKNLLRC---SWSPDGSKIAAGSADRFVYVW 313 Score = 54.7 bits (130), Expect = 2e-07 Identities = 33/122 (27%), Positives = 59/122 (48%), Gaps = 10/122 (8%) Frame = +2 Query: 50 NNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLL 229 N+ + I+SG D +KVW+L KL T+ GH V+ +++S +GS S D + Sbjct: 203 NDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRV 262 Query: 230 WDL---TEGKRLYSLDAGSIIN------SLCFSPNRYWLCAATQDS-IKIWDLESKHIVQ 379 WD+ +R + G++ N +SP+ + A + D + +WD S+ ++ Sbjct: 263 WDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRVLY 322 Query: 380 DL 385 L Sbjct: 323 KL 324 Score = 40.8 bits (94), Expect = 0.003 Identities = 30/126 (23%), Positives = 54/126 (42%), Gaps = 3/126 (2%) Frame = +2 Query: 137 LDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSL---DAGSIINSLCFSPN 307 L GH G V P+GS AS G D + LLW++ Y+ +G+++ + Sbjct: 63 LSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDG 122 Query: 308 RYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGT 487 A+T ++ +WD E+ V+ L+ + +C + G DGT Sbjct: 123 SMLFSASTDKTVAVWDSETGERVKRLKGHTSFVN------SCYPARRGPQLVCTGSDDGT 176 Query: 488 IRIYKI 505 ++++ I Sbjct: 177 VKLWDI 182 Score = 38.9 bits (89), Expect = 0.010 Identities = 19/49 (38%), Positives = 27/49 (55%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKD 214 I +GS DR V VW+ T+ ++ L GH G ++ VA PD + S D Sbjct: 301 IAAGSADRFVYVWDTTSRRVLYKLPGHAGSINEVAFHPDEPIILSASSD 349
>WDR57_HUMAN (Q96DI7) WD-repeat protein 57 (Prp8-binding protein) (hPRP8BP) (U5| snRNP-specific 40 kDa protein) (38 kDa splicing factor) Length = 357 Score = 70.1 bits (170), Expect = 4e-12 Identities = 53/207 (25%), Positives = 88/207 (42%), Gaps = 38/207 (18%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLT-NCKLRCTLDGHGGYVSAVAVSPDG 187 G G V C +F PN T+ S +DR + +WN+ +C TL GH G V + + DG Sbjct: 64 GHEGEVYCCKFHPNG--STLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDG 121 Query: 188 SLCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNR--YWLCAATQD-SIKIWDL 358 S+ S D +WD G+R+ L + + C+ R +C + D ++K+WD+ Sbjct: 122 SMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDI 181 Query: 359 ESKHIVQDLRPEVPV-------SSKQML---------------------------YCTCL 436 K +Q + V +S Q++ T L Sbjct: 182 RKKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGL 241 Query: 437 SWSADGSTLYAGYTDGTIRIYKISGFS 517 S S++GS L + D T+R++ + F+ Sbjct: 242 SLSSEGSYLLSNAMDNTVRVWDVRPFA 268 Score = 55.5 bits (132), Expect = 1e-07 Identities = 49/172 (28%), Positives = 78/172 (45%), Gaps = 8/172 (4%) Frame = +2 Query: 8 RGPTGWV-SCVRFSPNNFAPTIV-SGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSP 181 +G T +V SC P P +V +GS D +VK+W++ K + V AV + Sbjct: 148 KGHTSFVNSCY---PARRGPQLVCTGSDDGTVKLWDIRK-KAAIQTFQNTYQVLAVTFND 203 Query: 182 DGSLCASGGKDGVTLLWDLTEGKRLYSL--DAGSIINSLCFSPNRYWLCAATQDSIKIWD 355 SGG D +WDL + K Y++ A S+ S Y L A +++++WD Sbjct: 204 TSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWD 263 Query: 356 LE----SKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 + + V+ + V K +L C SWS DGS + AG D + ++ Sbjct: 264 VRPFAPKERCVKIFQGNVHNFEKNLLRC---SWSPDGSKIAAGSADRFVYVW 312 Score = 55.1 bits (131), Expect = 1e-07 Identities = 34/122 (27%), Positives = 59/122 (48%), Gaps = 10/122 (8%) Frame = +2 Query: 50 NNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLL 229 N+ + I+SG D +KVW+L KL T+ GH V+ +++S +GS S D + Sbjct: 202 NDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRV 261 Query: 230 WDL---TEGKRLYSLDAGSIIN------SLCFSPNRYWLCAATQDS-IKIWDLESKHIVQ 379 WD+ +R + G++ N +SP+ + A + D + +WD S+ I+ Sbjct: 262 WDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILY 321 Query: 380 DL 385 L Sbjct: 322 KL 323 Score = 40.8 bits (94), Expect = 0.003 Identities = 30/126 (23%), Positives = 54/126 (42%), Gaps = 3/126 (2%) Frame = +2 Query: 137 LDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSL---DAGSIINSLCFSPN 307 L GH G V P+GS AS G D + LLW++ Y+ +G+++ + Sbjct: 62 LSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDG 121 Query: 308 RYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGT 487 A+T ++ +WD E+ V+ L+ + +C + G DGT Sbjct: 122 SMLFSASTDKTVAVWDSETGERVKRLKGHTSFVN------SCYPARRGPQLVCTGSDDGT 175 Query: 488 IRIYKI 505 ++++ I Sbjct: 176 VKLWDI 181 Score = 39.3 bits (90), Expect = 0.008 Identities = 19/49 (38%), Positives = 27/49 (55%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKD 214 I +GS DR V VW+ T+ ++ L GH G ++ VA PD + S D Sbjct: 300 IAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSD 348
>KTNB1_STRPU (O61585) Katanin p80 WD40-containing subunit B1 (Katanin p80| subunit B1) (p80 katanin) Length = 690 Score = 69.7 bits (169), Expect = 5e-12 Identities = 44/154 (28%), Positives = 69/154 (44%), Gaps = 2/154 (1%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 + C+ F P F + SGS D +VK+W++ T GH V+ + SPDG + Sbjct: 104 IRCMDFHP--FGEFVASGSTDTNVKLWDVRRKGCIYTYKGHSDQVNMIKFSPDGKWLVTA 161 Query: 206 GKDGVTLLWDLTEGKRLYSL-DAGSIINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQ 379 +D LWDLT GK + + + F PN + L + + D +++ WDLE+ +V Sbjct: 162 SEDTTIKLWDLTMGKLFQEFKNHTGGVTGIEFHPNEFLLASGSSDRTVQFWDLETFQLVS 221 Query: 380 DLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTD 481 P +S+ DGS L+ D Sbjct: 222 STSPGASA-------VRSISFHPDGSYLFCSSQD 248 Score = 67.4 bits (163), Expect = 3e-11 Identities = 49/177 (27%), Positives = 83/177 (46%), Gaps = 2/177 (1%) Frame = +2 Query: 2 SARGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSP 181 S G T V V+F N+ +V+GS ++K+++L K+ TL GH + + P Sbjct: 54 SLSGHTSPVDSVKF--NSSEELVVAGSQSGTMKIYDLEPAKIVRTLTGHRNSIRCMDFHP 111 Query: 182 DGSLCASGGKDGVTLLWDLTEGKRLYSLDAGS-IINSLCFSPNRYWLCAATQD-SIKIWD 355 G ASG D LWD+ +Y+ S +N + FSP+ WL A++D +IK+WD Sbjct: 112 FGEFVASGSTDTNVKLWDVRRKGCIYTYKGHSDQVNMIKFSPDGKWLVTASEDTTIKLWD 171 Query: 356 LESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISGFSYSS 526 L + Q+ + T + + + L +G +D T++ + + F S Sbjct: 172 LTMGKLFQEFKNHTG-------GVTGIEFHPNEFLLASGSSDRTVQFWDLETFQLVS 221 Score = 48.5 bits (114), Expect = 1e-05 Identities = 37/163 (22%), Positives = 72/163 (44%), Gaps = 2/163 (1%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 V+C+ P + +V+G D+ V +W + +L GH V +V + L +G Sbjct: 19 VNCLALGPMS-GRVMVTGGEDKKVNLWAVGKQNCIISLSGHTSPVDSVKFNSSEELVVAG 77 Query: 206 GKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSP-NRYWLCAATQDSIKIWDLESKHIVQ 379 + G ++DL K + +L + I + F P + +T ++K+WD+ K + Sbjct: 78 SQSGTMKIYDLEPAKIVRTLTGHRNSIRCMDFHPFGEFVASGSTDTNVKLWDVRRKGCIY 137 Query: 380 DLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 + S Q+ + +S DG L D TI+++ ++ Sbjct: 138 TYKGH----SDQV---NMIKFSPDGKWLVTASEDTTIKLWDLT 173
>WD51A_HUMAN (Q8NBT0) WD-repeat protein 51A| Length = 407 Score = 69.7 bits (169), Expect = 5e-12 Identities = 48/163 (29%), Positives = 83/163 (50%), Gaps = 3/163 (1%) Frame = +2 Query: 23 WVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCAS 202 WV C +FSP+ IVS S D++VK+W+ ++ + + HGG+V+ V P G+ A+ Sbjct: 147 WVRCAKFSPDG--RLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAA 204 Query: 203 GGKDGVTLLWDLTEGKRL--YSLDAGSIINSLCFSPNRYWLCAATQDS-IKIWDLESKHI 373 G D +WD+ + L Y L + + +N L F P+ +L A+ DS +KI DL + Sbjct: 205 AGMDNTVKVWDVRTHRLLQHYQLHSAA-VNGLSFHPSGNYLITASSDSTLKILDLMEGRL 263 Query: 374 VQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYK 502 + L + T +++S G +G +D + ++K Sbjct: 264 LYTLHGHQGPA-------TTVAFSRTGEYFASGGSDEQVMVWK 299 Score = 59.3 bits (142), Expect = 7e-09 Identities = 44/165 (26%), Positives = 74/165 (44%), Gaps = 2/165 (1%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG 187 R T V V F + + V+ S D++VKVW K +L H +V SPDG Sbjct: 100 RAHTATVRSVHFCSDG--QSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDG 157 Query: 188 SLCASGGKDGVTLLWDLTEGKRLYS-LDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLE 361 L S D LWD + + ++S + G + + F P+ + AA D ++K+WD+ Sbjct: 158 RLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVR 217 Query: 362 SKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRI 496 + ++Q + + LS+ G+ L +D T++I Sbjct: 218 THRLLQHYQLHSAAVNG-------LSFHPSGNYLITASSDSTLKI 255 Score = 55.8 bits (133), Expect = 8e-08 Identities = 41/166 (24%), Positives = 74/166 (44%), Gaps = 2/166 (1%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG 187 +G V+CV FS N + SGS D + VW++ GH V+ V SP G Sbjct: 16 KGHRDAVTCVDFSINT--KQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSG 73 Query: 188 SLCASGGKDGVTLLW-DLTEGKRLYSLDAGSIINSLCF-SPNRYWLCAATQDSIKIWDLE 361 L ASG +D +W +G+ + + S+ F S + ++ A+ ++K+W Sbjct: 74 HLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATH 133 Query: 362 SKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 + + L S+ + + C +S DG + + D T++++ Sbjct: 134 RQKFLFSL-------SQHINWVRCAKFSPDGRLIVSASDDKTVKLW 172
>NLE1_MOUSE (Q8VEJ4) Notchless homolog 1| Length = 484 Score = 69.3 bits (168), Expect = 7e-12 Identities = 52/175 (29%), Positives = 81/175 (46%), Gaps = 8/175 (4%) Frame = +2 Query: 2 SARGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSP 181 S G + V V FSP + SGS D +V+ W+L+ T GH +V +++ SP Sbjct: 108 SLEGHSEAVISVAFSPTG--KYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSP 165 Query: 182 DGSLCASGGKDGVTLLWDLTEGKRLYSLDAG--SIINSLCFSP------NRYWLCAATQD 337 DG ASG K+G LLWD + G ++ G I L + P RY ++ Sbjct: 166 DGKKLASGCKNGQILLWDPSTGLQVGRTLTGHSKWITGLSWEPLHMNPECRYVASSSKDG 225 Query: 338 SIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYK 502 S+++WD + + + + TCL W DG LY+ D TI++++ Sbjct: 226 SVRVWDTTAGRCER-------ILTGHTQSVTCLRWGGDG-LLYSASQDRTIKVWR 272 Score = 63.9 bits (154), Expect = 3e-10 Identities = 56/210 (26%), Positives = 90/210 (42%), Gaps = 45/210 (21%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPD-- 184 G T V+C+R+ + + S S DR++KVW + L TL GHG +V+ +A+S D Sbjct: 243 GHTQSVTCLRWGGDGL---LYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMALSTDYA 299 Query: 185 -------------------GSL---------------------CASGGKDGVTLLWDLTE 244 GSL SG D LW E Sbjct: 300 LRTGAFEPAEATVNAQDLQGSLKELKERASSRYNLVRGQGPERLVSGSDDFTLFLWSPAE 359 Query: 245 GKRLYSLDAG--SIINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQDLRPEVPVSSKQ 415 K+ + G ++IN + FSP+ + +A+ D SIK+WD + + LR V + Sbjct: 360 DKKPLARMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQ- 418 Query: 416 MLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 ++WSAD L +G +D T++++ + Sbjct: 419 ------IAWSADSRLLVSGSSDSTLKVWDV 442 Score = 58.2 bits (139), Expect = 2e-08 Identities = 42/148 (28%), Positives = 75/148 (50%), Gaps = 3/148 (2%) Frame = +2 Query: 68 IVSGSWDRSVKVWN-LTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTE 244 +VSGS D ++ +W+ + K + GH ++ V SPD + AS D LWD Sbjct: 343 LVSGSDDFTLFLWSPAEDKKPLARMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 402 Query: 245 GKRLYSLDAG-SIINSLCFSPNRYWLCAATQDS-IKIWDLESKHIVQDLRPEVPVSSKQM 418 GK L SL + + + +S + L + + DS +K+WD++++ + DL P + ++ Sbjct: 403 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLATDL----PGHADEV 458 Query: 419 LYCTCLSWSADGSTLYAGYTDGTIRIYK 502 + WS DG + +G D +RI++ Sbjct: 459 Y---AVDWSPDGQRVASGGKDKCLRIWR 483 Score = 47.4 bits (111), Expect = 3e-05 Identities = 32/116 (27%), Positives = 56/116 (48%), Gaps = 2/116 (1%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G ++ V FSP++ + S S+D+S+K+W+ K +L GH V +A S D Sbjct: 369 GHQALINQVLFSPDS--RIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSR 426 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQDS-IKIW 352 L SG D +WD+ K L + ++ +SP+ + + +D ++IW Sbjct: 427 LLVSGSSDSTLKVWDVKAQKLATDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 482
>TAF5L_MOUSE (Q91WQ5) TAF5-like RNA polymerase II p300/CBP-associated| factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65-beta) Length = 589 Score = 68.9 bits (167), Expect = 9e-12 Identities = 40/115 (34%), Positives = 63/115 (54%), Gaps = 2/115 (1%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 V CV+F PN+ + +GS D++V++W+ GH G V +++ SP+G AS Sbjct: 429 VDCVKFHPNS--NYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLSFSPNGKYLASA 486 Query: 206 GKDGVTLLWDLTEGKRLYSLDAGS-IINSLCFSPNRYWLCAATQD-SIKIWDLES 364 G+D LWDL G L + I SL FSP+ + +A+ D S+++WD+ S Sbjct: 487 GEDQRLKLWDLASGTLFKELRGHTDSITSLAFSPDSGLIASASMDNSVRVWDIRS 541 Score = 65.1 bits (157), Expect = 1e-10 Identities = 44/153 (28%), Positives = 73/153 (47%), Gaps = 3/153 (1%) Frame = +2 Query: 56 FAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWD 235 F+ SGS DR+ ++W+ GH V V P+ + A+G D LW Sbjct: 395 FSLYFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWS 454 Query: 236 LTEGK--RLYSLDAGSIINSLCFSPNRYWLCAATQDS-IKIWDLESKHIVQDLRPEVPVS 406 +G RL++ G ++ SL FSPN +L +A +D +K+WDL S + ++LR Sbjct: 455 AQQGNSVRLFTGHRGPVL-SLSFSPNGKYLASAGEDQRLKLWDLASGTLFKELRGHTD-- 511 Query: 407 SKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 T L++S D + + D ++R++ I Sbjct: 512 -----SITSLAFSPDSGLIASASMDNSVRVWDI 539
>TAF5L_HUMAN (O75529) TAF5-like RNA polymerase II p300/CBP-associated| factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65-beta) Length = 589 Score = 68.6 bits (166), Expect = 1e-11 Identities = 42/118 (35%), Positives = 65/118 (55%), Gaps = 3/118 (2%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 V CV+F PN+ + +GS D++V++W+ GH G V ++A SP+G AS Sbjct: 429 VDCVKFHPNS--NYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASA 486 Query: 206 GKDGVTLLWDLTEGKRLYSLDAGSI--INSLCFSPNRYWLCAATQD-SIKIWDLESKH 370 G+D LWDL G LY G I SL FSP+ + +A+ D S+++WD+ + + Sbjct: 487 GEDQRLKLWDLASG-TLYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVWDIRNTY 543 Score = 64.7 bits (156), Expect = 2e-10 Identities = 43/147 (29%), Positives = 71/147 (48%), Gaps = 3/147 (2%) Frame = +2 Query: 74 SGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGK- 250 SGS DR+ ++W+ GH V V P+ + A+G D LW +G Sbjct: 401 SGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNS 460 Query: 251 -RLYSLDAGSIINSLCFSPNRYWLCAATQDS-IKIWDLESKHIVQDLRPEVPVSSKQMLY 424 RL++ G ++ SL FSPN +L +A +D +K+WDL S + ++LR Sbjct: 461 VRLFTGHRGPVL-SLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTD-------N 512 Query: 425 CTCLSWSADGSTLYAGYTDGTIRIYKI 505 T L++S D + + D ++R++ I Sbjct: 513 ITSLTFSPDSGLIASASMDNSVRVWDI 539
>GBB2_RAT (P54313) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 2 (Transducin beta chain 2) (G protein beta 2 subunit) Length = 339 Score = 68.6 bits (166), Expect = 1e-11 Identities = 48/167 (28%), Positives = 81/167 (48%), Gaps = 4/167 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G TG++SC RF +N I++ S D + +W++ + GH G V +++++PDG Sbjct: 140 GHTGYLSCCRFLDDN---QIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGR 196 Query: 191 LCASGGKDGVTLLWDLTEGK-RLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLES 364 SG D LWD+ + R + S IN++ F PN Y + D + +++DL + Sbjct: 197 TFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRA 256 Query: 365 KHIVQDLRPEVPVSSKQMLYC--TCLSWSADGSTLYAGYTDGTIRIY 499 E+ + S + C T +++S G L AGY D I+ Sbjct: 257 DQ-------ELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIW 296 Score = 55.1 bits (131), Expect = 1e-07 Identities = 47/167 (28%), Positives = 76/167 (45%), Gaps = 4/167 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G +G V + +P+ T VSG+ D S+K+W++ + R T GH ++AVA P+G Sbjct: 181 GHSGDVMSLSLAPDG--RTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGY 238 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSI---INSLCFSPNRYWLCAATQD-SIKIWDL 358 +G D L+DL + L +I I S+ FS + L A D + IWD Sbjct: 239 AFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWD- 297 Query: 359 ESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 ++ R V + +CL + DG + G D ++I+ Sbjct: 298 ----AMKGDRAGVLAGHDNRV--SCLGVTDDGMAVATGSWDSFLKIW 338 Score = 45.1 bits (105), Expect = 1e-04 Identities = 31/121 (25%), Positives = 56/121 (46%), Gaps = 7/121 (5%) Frame = +2 Query: 17 TGWVSCVRFSPN-NFAPTIVSGSWDRSVKVWNLT----NCKLRCTLDGHGGYVSAVAVSP 181 + WV ++P+ NF + G D +++L N ++ L GH GY+S Sbjct: 96 SSWVMTCAYAPSGNF---VACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLD 152 Query: 182 DGSLCASGGKDGVTLLWDLTEGKRL--YSLDAGSIINSLCFSPNRYWLCAATQDSIKIWD 355 D + S G D LWD+ G++ ++ +G +++ R ++ A SIK+WD Sbjct: 153 DNQIITSSG-DTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWD 211 Query: 356 L 358 + Sbjct: 212 V 212 Score = 32.3 bits (72), Expect = 0.94 Identities = 26/130 (20%), Positives = 56/130 (43%), Gaps = 2/130 (1%) Frame = +2 Query: 122 KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLD-AGSIINSLCF 298 + R TL GH + A+ D L S +DG ++WD +++++ S + + + Sbjct: 45 RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAY 104 Query: 299 SPN-RYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGY 475 +P+ + C + I+ L+++ + E+P + + C L D + + Sbjct: 105 APSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFL----DDNQIITSS 160 Query: 476 TDGTIRIYKI 505 D T ++ I Sbjct: 161 GDTTCALWDI 170 Score = 31.2 bits (69), Expect = 2.1 Identities = 15/56 (26%), Positives = 26/56 (46%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWD 235 +++G D + +W+ L GH VS + V+ DG A+G D +W+ Sbjct: 284 LLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 339
>GBB2_MOUSE (P62880) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 2 (Transducin beta chain 2) (G protein beta 2 subunit) Length = 339 Score = 68.6 bits (166), Expect = 1e-11 Identities = 48/167 (28%), Positives = 81/167 (48%), Gaps = 4/167 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G TG++SC RF +N I++ S D + +W++ + GH G V +++++PDG Sbjct: 140 GHTGYLSCCRFLDDN---QIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGR 196 Query: 191 LCASGGKDGVTLLWDLTEGK-RLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLES 364 SG D LWD+ + R + S IN++ F PN Y + D + +++DL + Sbjct: 197 TFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRA 256 Query: 365 KHIVQDLRPEVPVSSKQMLYC--TCLSWSADGSTLYAGYTDGTIRIY 499 E+ + S + C T +++S G L AGY D I+ Sbjct: 257 DQ-------ELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIW 296 Score = 55.1 bits (131), Expect = 1e-07 Identities = 47/167 (28%), Positives = 76/167 (45%), Gaps = 4/167 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G +G V + +P+ T VSG+ D S+K+W++ + R T GH ++AVA P+G Sbjct: 181 GHSGDVMSLSLAPDG--RTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGY 238 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSI---INSLCFSPNRYWLCAATQD-SIKIWDL 358 +G D L+DL + L +I I S+ FS + L A D + IWD Sbjct: 239 AFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWD- 297 Query: 359 ESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 ++ R V + +CL + DG + G D ++I+ Sbjct: 298 ----AMKGDRAGVLAGHDNRV--SCLGVTDDGMAVATGSWDSFLKIW 338 Score = 45.1 bits (105), Expect = 1e-04 Identities = 31/121 (25%), Positives = 56/121 (46%), Gaps = 7/121 (5%) Frame = +2 Query: 17 TGWVSCVRFSPN-NFAPTIVSGSWDRSVKVWNLT----NCKLRCTLDGHGGYVSAVAVSP 181 + WV ++P+ NF + G D +++L N ++ L GH GY+S Sbjct: 96 SSWVMTCAYAPSGNF---VACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLD 152 Query: 182 DGSLCASGGKDGVTLLWDLTEGKRL--YSLDAGSIINSLCFSPNRYWLCAATQDSIKIWD 355 D + S G D LWD+ G++ ++ +G +++ R ++ A SIK+WD Sbjct: 153 DNQIITSSG-DTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWD 211 Query: 356 L 358 + Sbjct: 212 V 212 Score = 32.3 bits (72), Expect = 0.94 Identities = 26/130 (20%), Positives = 56/130 (43%), Gaps = 2/130 (1%) Frame = +2 Query: 122 KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLD-AGSIINSLCF 298 + R TL GH + A+ D L S +DG ++WD +++++ S + + + Sbjct: 45 RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAY 104 Query: 299 SPN-RYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGY 475 +P+ + C + I+ L+++ + E+P + + C L D + + Sbjct: 105 APSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFL----DDNQIITSS 160 Query: 476 TDGTIRIYKI 505 D T ++ I Sbjct: 161 GDTTCALWDI 170 Score = 31.2 bits (69), Expect = 2.1 Identities = 15/56 (26%), Positives = 26/56 (46%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWD 235 +++G D + +W+ L GH VS + V+ DG A+G D +W+ Sbjct: 284 LLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 339
>GBB2_HUMAN (P62879) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 2 (Transducin beta chain 2) (G protein beta 2 subunit) Length = 339 Score = 68.6 bits (166), Expect = 1e-11 Identities = 48/167 (28%), Positives = 81/167 (48%), Gaps = 4/167 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G TG++SC RF +N I++ S D + +W++ + GH G V +++++PDG Sbjct: 140 GHTGYLSCCRFLDDN---QIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGR 196 Query: 191 LCASGGKDGVTLLWDLTEGK-RLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLES 364 SG D LWD+ + R + S IN++ F PN Y + D + +++DL + Sbjct: 197 TFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRA 256 Query: 365 KHIVQDLRPEVPVSSKQMLYC--TCLSWSADGSTLYAGYTDGTIRIY 499 E+ + S + C T +++S G L AGY D I+ Sbjct: 257 DQ-------ELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIW 296 Score = 55.1 bits (131), Expect = 1e-07 Identities = 47/167 (28%), Positives = 76/167 (45%), Gaps = 4/167 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G +G V + +P+ T VSG+ D S+K+W++ + R T GH ++AVA P+G Sbjct: 181 GHSGDVMSLSLAPDG--RTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGY 238 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSI---INSLCFSPNRYWLCAATQD-SIKIWDL 358 +G D L+DL + L +I I S+ FS + L A D + IWD Sbjct: 239 AFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWD- 297 Query: 359 ESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 ++ R V + +CL + DG + G D ++I+ Sbjct: 298 ----AMKGDRAGVLAGHDNRV--SCLGVTDDGMAVATGSWDSFLKIW 338 Score = 45.1 bits (105), Expect = 1e-04 Identities = 31/121 (25%), Positives = 56/121 (46%), Gaps = 7/121 (5%) Frame = +2 Query: 17 TGWVSCVRFSPN-NFAPTIVSGSWDRSVKVWNLT----NCKLRCTLDGHGGYVSAVAVSP 181 + WV ++P+ NF + G D +++L N ++ L GH GY+S Sbjct: 96 SSWVMTCAYAPSGNF---VACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLD 152 Query: 182 DGSLCASGGKDGVTLLWDLTEGKRL--YSLDAGSIINSLCFSPNRYWLCAATQDSIKIWD 355 D + S G D LWD+ G++ ++ +G +++ R ++ A SIK+WD Sbjct: 153 DNQIITSSG-DTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWD 211 Query: 356 L 358 + Sbjct: 212 V 212 Score = 32.3 bits (72), Expect = 0.94 Identities = 26/130 (20%), Positives = 56/130 (43%), Gaps = 2/130 (1%) Frame = +2 Query: 122 KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLD-AGSIINSLCF 298 + R TL GH + A+ D L S +DG ++WD +++++ S + + + Sbjct: 45 RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAY 104 Query: 299 SPN-RYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGY 475 +P+ + C + I+ L+++ + E+P + + C L D + + Sbjct: 105 APSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFL----DDNQIITSS 160 Query: 476 TDGTIRIYKI 505 D T ++ I Sbjct: 161 GDTTCALWDI 170 Score = 31.2 bits (69), Expect = 2.1 Identities = 15/56 (26%), Positives = 26/56 (46%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWD 235 +++G D + +W+ L GH VS + V+ DG A+G D +W+ Sbjct: 284 LLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 339
>GBB2_BOVIN (P11017) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 2 (Transducin beta chain 2) (G protein beta 2 subunit) (Fragment) Length = 326 Score = 68.6 bits (166), Expect = 1e-11 Identities = 48/167 (28%), Positives = 81/167 (48%), Gaps = 4/167 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G TG++SC RF +N I++ S D + +W++ + GH G V +++++PDG Sbjct: 127 GHTGYLSCCRFLDDN---QIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGR 183 Query: 191 LCASGGKDGVTLLWDLTEGK-RLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLES 364 SG D LWD+ + R + S IN++ F PN Y + D + +++DL + Sbjct: 184 TFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRA 243 Query: 365 KHIVQDLRPEVPVSSKQMLYC--TCLSWSADGSTLYAGYTDGTIRIY 499 E+ + S + C T +++S G L AGY D I+ Sbjct: 244 DQ-------ELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIW 283 Score = 55.1 bits (131), Expect = 1e-07 Identities = 47/167 (28%), Positives = 76/167 (45%), Gaps = 4/167 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G +G V + +P+ T VSG+ D S+K+W++ + R T GH ++AVA P+G Sbjct: 168 GHSGDVMSLSLAPDG--RTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGY 225 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSI---INSLCFSPNRYWLCAATQD-SIKIWDL 358 +G D L+DL + L +I I S+ FS + L A D + IWD Sbjct: 226 AFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWD- 284 Query: 359 ESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 ++ R V + +CL + DG + G D ++I+ Sbjct: 285 ----AMKGDRAGVLAGHDNRV--SCLGVTDDGMAVATGSWDSFLKIW 325 Score = 45.1 bits (105), Expect = 1e-04 Identities = 31/121 (25%), Positives = 56/121 (46%), Gaps = 7/121 (5%) Frame = +2 Query: 17 TGWVSCVRFSPN-NFAPTIVSGSWDRSVKVWNLT----NCKLRCTLDGHGGYVSAVAVSP 181 + WV ++P+ NF + G D +++L N ++ L GH GY+S Sbjct: 83 SSWVMTCAYAPSGNF---VACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLD 139 Query: 182 DGSLCASGGKDGVTLLWDLTEGKRL--YSLDAGSIINSLCFSPNRYWLCAATQDSIKIWD 355 D + S G D LWD+ G++ ++ +G +++ R ++ A SIK+WD Sbjct: 140 DNQIITSSG-DTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWD 198 Query: 356 L 358 + Sbjct: 199 V 199 Score = 32.3 bits (72), Expect = 0.94 Identities = 26/130 (20%), Positives = 56/130 (43%), Gaps = 2/130 (1%) Frame = +2 Query: 122 KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLD-AGSIINSLCF 298 + R TL GH + A+ D L S +DG ++WD +++++ S + + + Sbjct: 32 RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAY 91 Query: 299 SPN-RYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGY 475 +P+ + C + I+ L+++ + E+P + + C L D + + Sbjct: 92 APSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFL----DDNQIITSS 147 Query: 476 TDGTIRIYKI 505 D T ++ I Sbjct: 148 GDTTCALWDI 157 Score = 31.2 bits (69), Expect = 2.1 Identities = 15/56 (26%), Positives = 26/56 (46%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWD 235 +++G D + +W+ L GH VS + V+ DG A+G D +W+ Sbjct: 271 LLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 326
>WD51B_PONPY (Q5RD06) WD-repeat protein 51B| Length = 451 Score = 68.2 bits (165), Expect = 2e-11 Identities = 48/166 (28%), Positives = 82/166 (49%), Gaps = 4/166 (2%) Frame = +2 Query: 17 TGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLC 196 T WV C +FSP+ IVS S D+++K+W+ TN + G+ + V +P G+ Sbjct: 144 THWVRCAKFSPDG--RLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCI 201 Query: 197 ASGGKDGVTLLWDLTEGKRL--YSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLESK 367 AS G D +WD+ K L Y + +G +N + F P+ +L A+ D ++KI DL Sbjct: 202 ASAGSDQTVKVWDVRVNKLLQHYQVHSGG-VNCISFHPSDNYLVTASSDGTLKILDLLEG 260 Query: 368 HIVQDLRPEV-PVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYK 502 ++ L+ PV + +S+S G +G D + +++ Sbjct: 261 RLIYTLQGHTGPVFT--------VSFSKGGELFASGGADTQVLLWR 298 Score = 57.8 bits (138), Expect = 2e-08 Identities = 38/145 (26%), Positives = 72/145 (49%), Gaps = 2/145 (1%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 + + S D+S+KVW++ + +L H +V SPDG L S +D +WD T Sbjct: 117 LATASEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNK 176 Query: 248 KRLYSL-DAGSIINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQDLRPEVPVSSKQML 421 + + + D+ N + F+P+ + +A D ++K+WD+ ++Q + V S + Sbjct: 177 QCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQ----VHSGGV- 231 Query: 422 YCTCLSWSADGSTLYAGYTDGTIRI 496 C+S+ + L +DGT++I Sbjct: 232 --NCISFHPSDNYLVTASSDGTLKI 254 Score = 57.8 bits (138), Expect = 2e-08 Identities = 42/166 (25%), Positives = 74/166 (44%), Gaps = 2/166 (1%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG 187 +G ++ + SPN + + SWD + +WN GH V++V SP G Sbjct: 15 KGHKAAITSLDLSPNG--KQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHG 72 Query: 188 SLCASGGKDGVTLLWDLTEGKRLYSLDAGSI-INSLCFSPNRYWLCAATQD-SIKIWDLE 361 +L AS +D LW + + A + + S+ FS + +L A++D SIK+W + Sbjct: 73 NLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMY 132 Query: 362 SKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 + + L + + C +S DG + + D TI+I+ Sbjct: 133 RQRFLYSL-------YRHTHWVRCAKFSPDGRLIVSCSEDKTIKIW 171
>WD51B_HUMAN (Q8TC44) WD-repeat protein 51B| Length = 478 Score = 68.2 bits (165), Expect = 2e-11 Identities = 48/166 (28%), Positives = 82/166 (49%), Gaps = 4/166 (2%) Frame = +2 Query: 17 TGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLC 196 T WV C +FSP+ IVS S D+++K+W+ TN + G+ + V +P G+ Sbjct: 144 THWVRCAKFSPDG--RLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCI 201 Query: 197 ASGGKDGVTLLWDLTEGKRL--YSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLESK 367 AS G D +WD+ K L Y + +G +N + F P+ +L A+ D ++KI DL Sbjct: 202 ASAGSDQTVKVWDVRVNKLLQHYQVHSGG-VNCISFHPSGNYLITASSDGTLKILDLLEG 260 Query: 368 HIVQDLRPEV-PVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYK 502 ++ L+ PV + +S+S G +G D + +++ Sbjct: 261 RLIYTLQGHTGPVFT--------VSFSKGGELFASGGADTQVLLWR 298 Score = 60.5 bits (145), Expect = 3e-09 Identities = 39/145 (26%), Positives = 73/145 (50%), Gaps = 2/145 (1%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 + + S D+S+KVW++ + +L H +V SPDG L S +D +WD T Sbjct: 117 LATASEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNK 176 Query: 248 KRLYSL-DAGSIINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQDLRPEVPVSSKQML 421 + + + D+ N + F+P+ + +A D ++K+WD+ ++Q + V S + Sbjct: 177 QCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQ----VHSGGV- 231 Query: 422 YCTCLSWSADGSTLYAGYTDGTIRI 496 C+S+ G+ L +DGT++I Sbjct: 232 --NCISFHPSGNYLITASSDGTLKI 254 Score = 57.8 bits (138), Expect = 2e-08 Identities = 42/166 (25%), Positives = 74/166 (44%), Gaps = 2/166 (1%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG 187 +G ++ + SPN + + SWD + +WN GH V++V SP G Sbjct: 15 KGHKAAITSLDLSPNG--KQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHG 72 Query: 188 SLCASGGKDGVTLLWDLTEGKRLYSLDAGSI-INSLCFSPNRYWLCAATQD-SIKIWDLE 361 +L AS +D LW + + A + + S+ FS + +L A++D SIK+W + Sbjct: 73 NLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMY 132 Query: 362 SKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 + + L + + C +S DG + + D TI+I+ Sbjct: 133 RQRFLYSL-------YRHTHWVRCAKFSPDGRLIVSCSEDKTIKIW 171
>GNB1L_MOUSE (Q9EQ15) Guanine nucleotide-binding protein beta subunit-like| protein 1 (G protein beta subunit-like protein 1) (WD40 repeat-containing protein deleted in VCFS) (WDVCF protein) Length = 326 Score = 67.8 bits (164), Expect = 2e-11 Identities = 58/182 (31%), Positives = 86/182 (47%), Gaps = 15/182 (8%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFA---PTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGY-VSAVAV 175 RG V+ + F P + A P + SGS + V +W+L ++ TL+GHGG V + Sbjct: 16 RGTQSAVNTLHFCPPSQAAGNPLLFSGSQNGLVHIWSLQTRRIVTTLNGHGGQGVIWLKT 75 Query: 176 SPDGSLCASGGKDGVTLLWDLTEGKRL----YSLDA-GSIINSLCFSPNRYWLCAAT--- 331 P G S G+D LWDL EG+ LD+ G S+ + W+ A Sbjct: 76 LPQGHQLLSQGRDLRLCLWDLEEGRNTIMDSVQLDSVGFCRGSILVRGQQCWMLAVPGKG 135 Query: 332 QDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGS---TLYAGYTDGTIRIYK 502 D ++I ++ SK V L+PE + M C L W + S L AGY DG++ ++ Sbjct: 136 SDEVQILEMPSKTSVCTLKPEAD-ARPGMPMCLGL-WQTNSSLRPLLLAGYEDGSVTLWD 193 Query: 503 IS 508 IS Sbjct: 194 IS 195
>WDR57_PONPY (Q5RF51) WD-repeat protein 57| Length = 357 Score = 67.4 bits (163), Expect = 3e-11 Identities = 52/207 (25%), Positives = 88/207 (42%), Gaps = 38/207 (18%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLT-NCKLRCTLDGHGGYVSAVAVSPDG 187 G G V C +F PN T+ S +DR + +WN+ +C TL G+ G V + + DG Sbjct: 64 GHEGEVYCCKFHPNG--STLASAGFDRLILLWNVYGDCGNYATLKGYSGAVMELHYNTDG 121 Query: 188 SLCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNR--YWLCAATQD-SIKIWDL 358 S+ S D +WD G+R+ L + + C+ R +C + D ++K+WD+ Sbjct: 122 SMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDI 181 Query: 359 ESKHIVQDLRPEVPV-------SSKQML---------------------------YCTCL 436 K +Q + V +S Q++ T L Sbjct: 182 RKKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGL 241 Query: 437 SWSADGSTLYAGYTDGTIRIYKISGFS 517 S S++GS L + D T+R++ + F+ Sbjct: 242 SLSSEGSYLLSNAMDNTVRVWDVRPFA 268 Score = 56.6 bits (135), Expect = 5e-08 Identities = 35/122 (28%), Positives = 60/122 (49%), Gaps = 10/122 (8%) Frame = +2 Query: 50 NNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLL 229 N+ + I+SG D +KVW+L KL T+ GH V+ +++S +GS S D + Sbjct: 202 NDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRV 261 Query: 230 WDL---TEGKRLYSLDAGSIIN------SLCFSPNRYWLCAATQD-SIKIWDLESKHIVQ 379 WD+ +R + G++ N +SP+ + A + D S+ +WD S+ I+ Sbjct: 262 WDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRSVCVWDTTSRRILY 321 Query: 380 DL 385 L Sbjct: 322 KL 323 Score = 56.2 bits (134), Expect = 6e-08 Identities = 49/172 (28%), Positives = 79/172 (45%), Gaps = 8/172 (4%) Frame = +2 Query: 8 RGPTGWV-SCVRFSPNNFAPTIV-SGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSP 181 +G T +V SC P P +V +GS D +VK+W++ K + V AV + Sbjct: 148 KGHTSFVNSCY---PARRGPQLVCTGSDDGTVKLWDIRK-KAAIQTFQNTYQVLAVTFND 203 Query: 182 DGSLCASGGKDGVTLLWDLTEGKRLYSL--DAGSIINSLCFSPNRYWLCAATQDSIKIWD 355 SGG D +WDL + K Y++ A S+ S Y L A +++++WD Sbjct: 204 TSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWD 263 Query: 356 LE----SKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 + + V+ + V K +L C SWS DGS + AG D ++ ++ Sbjct: 264 VRPFAPKERCVKIFQGNVHNFEKNLLRC---SWSPDGSKIAAGSADRSVCVW 312 Score = 41.2 bits (95), Expect = 0.002 Identities = 20/49 (40%), Positives = 28/49 (57%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKD 214 I +GS DRSV VW+ T+ ++ L GH G ++ VA PD + S D Sbjct: 300 IAAGSADRSVCVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSD 348 Score = 40.0 bits (92), Expect = 0.004 Identities = 30/126 (23%), Positives = 54/126 (42%), Gaps = 3/126 (2%) Frame = +2 Query: 137 LDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSL---DAGSIINSLCFSPN 307 L GH G V P+GS AS G D + LLW++ Y+ +G+++ + Sbjct: 62 LSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCGNYATLKGYSGAVMELHYNTDG 121 Query: 308 RYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGT 487 A+T ++ +WD E+ V+ L+ + +C + G DGT Sbjct: 122 SMLFSASTDKTVAVWDSETGERVKRLKGHTSFVN------SCYPARRGPQLVCTGSDDGT 175 Query: 488 IRIYKI 505 ++++ I Sbjct: 176 VKLWDI 181
>TUP1_KLULA (P56094) Transcriptional repressor TUP1| Length = 682 Score = 67.4 bits (163), Expect = 3e-11 Identities = 37/167 (22%), Positives = 83/167 (49%), Gaps = 2/167 (1%) Frame = +2 Query: 23 WVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCAS 202 ++ V FSP+ + +G+ D+ +++W+L K+ TL GH + ++ P G+ S Sbjct: 408 YIRSVCFSPDG--KFLATGAEDKLIRIWDLETKKIVMTLKGHEQDIYSLDYFPSGNKLVS 465 Query: 203 GGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSP--NRYWLCAATQDSIKIWDLESKHIV 376 G D +WDLT G +L + ++ SP ++ + ++++WD ++ +V Sbjct: 466 GSGDRTVRIWDLTTGTCSLTLSIEDGVTTVAVSPGEGKFIAAGSLDRTVRVWDSDTGFLV 525 Query: 377 QDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISGFS 517 + L E + + + ++ DG + +G D +++++ ++G S Sbjct: 526 ERLDSENELGTGHRDSVYSVVFTRDGKGVVSGSLDRSVKLWNLNGLS 572 Score = 50.1 bits (118), Expect = 4e-06 Identities = 28/73 (38%), Positives = 37/73 (50%), Gaps = 7/73 (9%) Frame = +2 Query: 68 IVSGSWDRSVKVWNL-------TNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTL 226 +VSGS DRSVK+WNL ++ + T GH +V +VA + + SG KD L Sbjct: 554 VVSGSLDRSVKLWNLNGLSGQKSHAECEVTYTGHKDFVLSVATTQNDEYILSGSKDRGVL 613 Query: 227 LWDLTEGKRLYSL 265 WD G L L Sbjct: 614 FWDTKSGNPLLML 626 Score = 29.3 bits (64), Expect = 7.9 Identities = 19/61 (31%), Positives = 28/61 (45%), Gaps = 6/61 (9%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVS------PDGSLCASGGKDGVTLL 229 I+SGS DR V W+ + L GH V +V V+ P+ + A+G D + Sbjct: 603 ILSGSKDRGVLFWDTKSGNPLLMLQGHRNSVISVTVANGHPLGPEYGVFATGSGDCKARI 662 Query: 230 W 232 W Sbjct: 663 W 663
>GBB4_RAT (O35353) Guanine nucleotide-binding protein beta subunit 4| (Transducin beta chain 4) Length = 339 Score = 67.4 bits (163), Expect = 3e-11 Identities = 47/161 (29%), Positives = 79/161 (49%), Gaps = 4/161 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G TG++SC RF + I++ S D + +W++ + T GH G V ++++SPD Sbjct: 140 GHTGYLSCCRFLDDG---QIITSSGDTTCALWDIETGQQTTTFTGHSGDVMSLSLSPDLK 196 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAG-SIINSLCFSPNRYWLCAATQD-SIKIWDLES 364 SG D + LWD+ +G S S IN++ F P+ Y + D + +++DL + Sbjct: 197 TFVSGACDASSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFDLRA 256 Query: 365 KHIVQDLRPEVPVSSKQMLYC--TCLSWSADGSTLYAGYTD 481 E+ + S + C T +++S G L AGY D Sbjct: 257 DQ-------ELLLYSHDNIICGITSVAFSKSGRLLLAGYDD 290 Score = 34.7 bits (78), Expect = 0.19 Identities = 25/116 (21%), Positives = 53/116 (45%), Gaps = 2/116 (1%) Frame = +2 Query: 122 KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLD-AGSIINSLCF 298 + R TL GH + A+ D L S +DG ++WD +++++ S + + + Sbjct: 45 RTRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAY 104 Query: 299 SPN-RYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTL 463 +P+ Y C + I++L+++ + E+P + Y +C + DG + Sbjct: 105 APSGNYVACGGLDNICSIYNLKTREGNVRVSRELPGHTG---YLSCCRFLDDGQII 157 Score = 31.2 bits (69), Expect = 2.1 Identities = 16/56 (28%), Positives = 26/56 (46%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWD 235 +++G D + VW+ L GH VS + V+ DG A+G D +W+ Sbjct: 284 LLAGYDDFNCSVWDALKGGRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN 339 Score = 29.3 bits (64), Expect = 7.9 Identities = 35/151 (23%), Positives = 61/151 (40%), Gaps = 5/151 (3%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL--T 241 +VS S D + +W+ + +V A +P G+ A GG D + +++L Sbjct: 69 LVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTR 128 Query: 242 EGKRLYS--LDAGSIINSLC-FSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSK 412 EG S L + S C F + + ++ + +WD+E+ Q S Sbjct: 129 EGNVRVSRELPGHTGYLSCCRFLDDGQIITSSGDTTCALWDIETG---QQTTTFTGHSGD 185 Query: 413 QMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 M LS S D T +G D + +++ I Sbjct: 186 VM----SLSLSPDLKTFVSGACDASSKLWDI 212
>GBB4_MOUSE (P29387) Guanine nucleotide-binding protein beta subunit 4| (Transducin beta chain 4) Length = 339 Score = 67.4 bits (163), Expect = 3e-11 Identities = 47/161 (29%), Positives = 79/161 (49%), Gaps = 4/161 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G TG++SC RF + I++ S D + +W++ + T GH G V ++++SPD Sbjct: 140 GHTGYLSCCRFLDDG---QIITSSGDTTCALWDIETGQQTTTFTGHSGDVMSLSLSPDLK 196 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAG-SIINSLCFSPNRYWLCAATQD-SIKIWDLES 364 SG D + LWD+ +G S S IN++ F P+ Y + D + +++DL + Sbjct: 197 TFVSGACDASSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRLFDLRA 256 Query: 365 KHIVQDLRPEVPVSSKQMLYC--TCLSWSADGSTLYAGYTD 481 E+ + S + C T +++S G L AGY D Sbjct: 257 DQ-------ELLLYSHDNIICGITSVAFSKSGRLLLAGYDD 290 Score = 34.7 bits (78), Expect = 0.19 Identities = 25/116 (21%), Positives = 53/116 (45%), Gaps = 2/116 (1%) Frame = +2 Query: 122 KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLD-AGSIINSLCF 298 + R TL GH + A+ D L S +DG ++WD +++++ S + + + Sbjct: 45 RTRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAY 104 Query: 299 SPN-RYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTL 463 +P+ Y C + I++L+++ + E+P + Y +C + DG + Sbjct: 105 APSGNYVACGGLDNICSIYNLKTREGNVRVSRELPGHTG---YLSCCRFLDDGQII 157 Score = 31.2 bits (69), Expect = 2.1 Identities = 16/56 (28%), Positives = 26/56 (46%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWD 235 +++G D + VW+ L GH VS + V+ DG A+G D +W+ Sbjct: 284 LLAGYDDFNCSVWDALKGGRSGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN 339 Score = 29.3 bits (64), Expect = 7.9 Identities = 35/151 (23%), Positives = 61/151 (40%), Gaps = 5/151 (3%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL--T 241 +VS S D + +W+ + +V A +P G+ A GG D + +++L Sbjct: 69 LVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTR 128 Query: 242 EGKRLYS--LDAGSIINSLC-FSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSK 412 EG S L + S C F + + ++ + +WD+E+ Q S Sbjct: 129 EGNVRVSRELPGHTGYLSCCRFLDDGQIITSSGDTTCALWDIETG---QQTTTFTGHSGD 185 Query: 413 QMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 M LS S D T +G D + +++ I Sbjct: 186 VM----SLSLSPDLKTFVSGACDASSKLWDI 212
>PRP46_YARLI (Q6C709) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 472 Score = 67.4 bits (163), Expect = 3e-11 Identities = 50/167 (29%), Positives = 76/167 (45%), Gaps = 2/167 (1%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G GWV V P N +GS D+++K+W+L KLR TL GH V A+ VSP Sbjct: 161 GHQGWVRSVCVEPEN--QWFATGSADKTIKIWDLATGKLRLTLTGHIMGVRALGVSPRHP 218 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAG-SIINSLCFSPNRYWLCAATQDSI-KIWDLES 364 SGG+D + WDL K + S + SL P L +A +D++ ++WD+ + Sbjct: 219 YMFSGGEDKMVKCWDLETNKVVRHYHGHLSAVYSLDIHPTLDVLVSAGRDAVARVWDIRT 278 Query: 365 KHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 R V V S + + A + D T+R++ + Sbjct: 279 -------RDPVVVLSGHKSTINRVKFQASEPQVITASADETVRLWNL 318 Score = 49.3 bits (116), Expect = 7e-06 Identities = 28/84 (33%), Positives = 45/84 (53%), Gaps = 3/84 (3%) Frame = +2 Query: 137 LDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLDAGSI--INSLCFSPNR 310 + GH G+V +V V P+ A+G D +WDL GK +L G I + +L SP Sbjct: 159 ITGHQGWVRSVCVEPENQWFATGSADKTIKIWDLATGKLRLTL-TGHIMGVRALGVSPRH 217 Query: 311 YWLCAATQDS-IKIWDLESKHIVQ 379 ++ + +D +K WDLE+ +V+ Sbjct: 218 PYMFSGGEDKMVKCWDLETNKVVR 241 Score = 35.4 bits (80), Expect = 0.11 Identities = 31/145 (21%), Positives = 54/145 (37%), Gaps = 1/145 (0%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 +VS D +VW++ L GH ++ V + D LW+L G Sbjct: 262 LVSAGRDAVARVWDIRTRDPVVVLSGHKSTINRVKFQASEPQVITASADETVRLWNLQAG 321 Query: 248 KRLYSL-DAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLY 424 K + +L + L P + A+ +S K W +V + Q Sbjct: 322 KTMTTLTHHKKSVRGLTLHPEEFTFSTASANSSKQWKCPEGDLVLNY-------DDQNAI 374 Query: 425 CTCLSWSADGSTLYAGYTDGTIRIY 499 LS + D + +++G +G+I Y Sbjct: 375 INTLSVNQD-NVMFSGGDNGSIGFY 398
>WSB2_HUMAN (Q9NYS7) WD repeat and SOCS box-containing protein 2 (WSB-2) (CS| box-containing WD protein) Length = 404 Score = 66.6 bits (161), Expect = 4e-11 Identities = 46/177 (25%), Positives = 76/177 (42%), Gaps = 14/177 (7%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G WV C SP+ + S + ++SV +W++ + L L+GH V + SPD + Sbjct: 195 GHLQWVYCCSISPD--CSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCDFSPDSA 252 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSI-------------INSLCFSPNRYWLCAAT 331 L + D ++WD G+RL SL + + S+CFSP +L Sbjct: 253 LLVTASYDTNVIMWDPYTGERLRSLHHTQVDPAMDDSDVHISSLRSVCFSPEGLYLATVA 312 Query: 332 QDS-IKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 D ++IW LE K P++ M C ++ G + G DG ++ + Sbjct: 313 DDRLLRIWALELK---------TPIAFAPMTNGLCCTFFPHGGVIATGTRDGHVQFW 360 Score = 46.6 bits (109), Expect = 5e-05 Identities = 30/110 (27%), Positives = 53/110 (48%), Gaps = 4/110 (3%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSL-CASGGKDGVTLLWDLTE 244 + +G D +K+W + L L GH V ++ +P GSL S +D +WDL + Sbjct: 126 LATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNK 185 Query: 245 GKRLYSLDAGSIINSLC--FSPNRYWLC-AATQDSIKIWDLESKHIVQDL 385 + + +G + C SP+ LC AA + S+ +W + S +++ L Sbjct: 186 HGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKL 235
>KTNB1_HUMAN (Q9BVA0) Katanin p80 WD40-containing subunit B1 (Katanin p80| subunit B1) (p80 katanin) Length = 655 Score = 66.2 bits (160), Expect = 6e-11 Identities = 52/178 (29%), Positives = 82/178 (46%), Gaps = 3/178 (1%) Frame = +2 Query: 2 SARGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSP 181 S G T V VR N IV+GS S++VW+L K+ TL GH + ++ P Sbjct: 58 SLTGHTSPVESVRL--NTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHP 115 Query: 182 DGSLCASGGKDGVTLLWDLTEGKRLYSLDAGS-IINSLCFSPNRYWLCAATQD-SIKIWD 355 G ASG +D LWD+ ++ S + L FSP+ WL +A D ++K+WD Sbjct: 116 YGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWD 175 Query: 356 LESKHIVQDLRPEV-PVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISGFSYSS 526 L + ++ + PV+ + + + L +G +D TIR + + F S Sbjct: 176 LTAGKMMSEFPGHTGPVN--------VVEFHPNEYLLASGSSDRTIRFWDLEKFQVVS 225 Score = 63.2 bits (152), Expect = 5e-10 Identities = 38/119 (31%), Positives = 63/119 (52%), Gaps = 1/119 (0%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG 187 RG + V C+RFSP+ + S + D +VK+W+LT K+ GH G V+ V P+ Sbjct: 144 RGHSQAVRCLRFSPDG--KWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNE 201 Query: 188 SLCASGGKDGVTLLWDLTEGKRLYSLDAG-SIINSLCFSPNRYWLCAATQDSIKIWDLE 361 L ASG D WDL + + + ++ + S+ F+P+ L + QDS++++ E Sbjct: 202 YLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDSLRVYGWE 260 Score = 55.1 bits (131), Expect = 1e-07 Identities = 40/149 (26%), Positives = 68/149 (45%), Gaps = 2/149 (1%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 + +G D V +W++ +L GH V +V ++ L +G + G +WDL Sbjct: 36 LATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAA 95 Query: 248 KRLYSLDAGSI-INSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQDLRPEVPVSSKQML 421 K L +L I SL F P ++ + +QD +IK+WD+ K V R Sbjct: 96 KILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQA------ 149 Query: 422 YCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 CL +S DG L + D T++++ ++ Sbjct: 150 -VRCLRFSPDGKWLASAADDHTVKLWDLT 177 Score = 34.7 bits (78), Expect = 0.19 Identities = 25/83 (30%), Positives = 42/83 (50%), Gaps = 3/83 (3%) Frame = +2 Query: 146 HGGYVSAVAVSP-DGSLCASGGKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWL 319 H VS++ + G L A+GG D LW + + + SL S + S+ + + Sbjct: 19 HASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELI 78 Query: 320 CAATQD-SIKIWDLESKHIVQDL 385 A +Q SI++WDLE+ I++ L Sbjct: 79 VAGSQSGSIRVWDLEAAKILRTL 101
>TUP12_SCHPO (Q9UUG8) Transcriptional repressor tup12| Length = 586 Score = 66.2 bits (160), Expect = 6e-11 Identities = 45/173 (26%), Positives = 86/173 (49%), Gaps = 1/173 (0%) Frame = +2 Query: 23 WVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCAS 202 +V V FSP+ + +G D+ +++W++ ++ L GH + ++ S DG S Sbjct: 336 YVRSVAFSPDG--KYLATGVEDQQIRIWDIAQKRVYRLLTGHEQEIYSLDFSKDGKTLVS 393 Query: 203 GGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDS-IKIWDLESKHIVQ 379 G D LWD+ G++ L + ++ FSP+ ++ A + D I+IW S +V+ Sbjct: 394 GSGDRTVCLWDVEAGEQKLILHTDDGVTTVMFSPDGQFIAAGSLDKVIRIW-TSSGTLVE 452 Query: 380 DLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISGFSYSS*IMY 538 L ++ +Y +++S DG L +G D TI+++++ S + MY Sbjct: 453 QLH-----GHEESVY--SVAFSPDGKYLVSGSLDNTIKLWELQCVSNVAPSMY 498 Score = 47.4 bits (111), Expect = 3e-05 Identities = 36/126 (28%), Positives = 52/126 (41%), Gaps = 14/126 (11%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCK------------LRCTLDGHGGYVSAV 169 V V FSP+ +VSGS D ++K+W L + T GH ++ +V Sbjct: 461 VYSVAFSPDG--KYLVSGSLDNTIKLWELQCVSNVAPSMYKEGGICKQTFTGHKDFILSV 518 Query: 170 AVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQD-SI 343 VSPDG SG KD W +L + + S+ SPN + + D Sbjct: 519 TVSPDGKWIISGSKDRTIQFWSPDSPHSQLTLQGHNNSVISVAVSPNGHCFATGSGDLRA 578 Query: 344 KIWDLE 361 +IW E Sbjct: 579 RIWSYE 584 Score = 45.4 bits (106), Expect = 1e-04 Identities = 26/74 (35%), Positives = 40/74 (54%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G ++ V SP+ I+SGS DR+++ W+ + + TL GH V +VAVSP+G Sbjct: 510 GHKDFILSVTVSPDG--KWIISGSKDRTIQFWSPDSPHSQLTLQGHNNSVISVAVSPNGH 567 Query: 191 LCASGGKDGVTLLW 232 A+G D +W Sbjct: 568 CFATGSGDLRARIW 581 Score = 33.5 bits (75), Expect = 0.42 Identities = 25/87 (28%), Positives = 47/87 (54%), Gaps = 2/87 (2%) Frame = +2 Query: 254 LYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQM--LYC 427 L++L+ S+I + FS + +L + ++++E+ ++ L+ E SSK+ LY Sbjct: 281 LHTLEHTSVICYVRFSADGKFLATGCNRAAMVFNVETGKLITLLQEE---SSKREGDLYV 337 Query: 428 TCLSWSADGSTLYAGYTDGTIRIYKIS 508 +++S DG L G D IRI+ I+ Sbjct: 338 RSVAFSPDGKYLATGVEDQQIRIWDIA 364
>KTNB1_MOUSE (Q8BG40) Katanin p80 WD40-containing subunit B1 (Katanin p80| subunit B1) (p80 katanin) Length = 658 Score = 66.2 bits (160), Expect = 6e-11 Identities = 52/178 (29%), Positives = 82/178 (46%), Gaps = 3/178 (1%) Frame = +2 Query: 2 SARGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSP 181 S G T V VR N IV+GS S++VW+L K+ TL GH + ++ P Sbjct: 58 SLTGHTSPVESVRL--NTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHP 115 Query: 182 DGSLCASGGKDGVTLLWDLTEGKRLYSLDAGS-IINSLCFSPNRYWLCAATQD-SIKIWD 355 G ASG +D LWD+ ++ S + L FSP+ WL +A D ++K+WD Sbjct: 116 YGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWD 175 Query: 356 LESKHIVQDLRPEV-PVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISGFSYSS 526 L + ++ + PV+ + + + L +G +D TIR + + F S Sbjct: 176 LTAGKMMSEFPGHTGPVN--------VVEFHPNEYLLASGSSDRTIRFWDLEKFQVVS 225 Score = 63.2 bits (152), Expect = 5e-10 Identities = 38/119 (31%), Positives = 63/119 (52%), Gaps = 1/119 (0%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG 187 RG + V C+RFSP+ + S + D +VK+W+LT K+ GH G V+ V P+ Sbjct: 144 RGHSQAVRCLRFSPDG--KWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNE 201 Query: 188 SLCASGGKDGVTLLWDLTEGKRLYSLDAG-SIINSLCFSPNRYWLCAATQDSIKIWDLE 361 L ASG D WDL + + + ++ + S+ F+P+ L + QDS++++ E Sbjct: 202 YLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDSLRVYGWE 260 Score = 55.1 bits (131), Expect = 1e-07 Identities = 40/149 (26%), Positives = 68/149 (45%), Gaps = 2/149 (1%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 + +G D V +W++ +L GH V +V ++ L +G + G +WDL Sbjct: 36 LATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAA 95 Query: 248 KRLYSLDAGSI-INSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQDLRPEVPVSSKQML 421 K L +L I SL F P ++ + +QD +IK+WD+ K V R Sbjct: 96 KILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQA------ 149 Query: 422 YCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 CL +S DG L + D T++++ ++ Sbjct: 150 -VRCLRFSPDGKWLASAADDHTVKLWDLT 177 Score = 34.7 bits (78), Expect = 0.19 Identities = 25/83 (30%), Positives = 42/83 (50%), Gaps = 3/83 (3%) Frame = +2 Query: 146 HGGYVSAVAVSP-DGSLCASGGKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWL 319 H VS++ + G L A+GG D LW + + + SL S + S+ + + Sbjct: 19 HASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELI 78 Query: 320 CAATQD-SIKIWDLESKHIVQDL 385 A +Q SI++WDLE+ I++ L Sbjct: 79 VAGSQSGSIRVWDLEAAKILRTL 101
>Y163_SYNY3 (Q55563) Hypothetical WD-repeat protein sll0163| Length = 1693 Score = 66.2 bits (160), Expect = 6e-11 Identities = 47/171 (27%), Positives = 76/171 (44%), Gaps = 3/171 (1%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG 187 RG WV V FSP++ +V+ D + ++WN +L GH +V + G Sbjct: 1093 RGHEDWVRSVHFSPHH--QFLVTSGQDNTARIWNFAGEQL-TLCQGHADWVRNAEFNCHG 1149 Query: 188 SLCASGGKDGVTLLWDLTEGKRLYSLDAG--SIINSLCFSPNRYWLCAATQD-SIKIWDL 358 + + +DG LWDL EG+ + L G S + + FSP+ W+ + D + ++WDL Sbjct: 1150 QILLTASRDGTARLWDL-EGREI-GLCQGHTSWVRNAQFSPDGQWIVTCSADGTARLWDL 1207 Query: 359 ESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISG 511 S+ V + WS DG + +DGT R++ G Sbjct: 1208 SSQCFA--------VLKGHQNWVNNALWSPDGQHIITSSSDGTARVWSRHG 1250 Score = 58.9 bits (141), Expect = 9e-09 Identities = 37/111 (33%), Positives = 59/111 (53%), Gaps = 2/111 (1%) Frame = +2 Query: 38 RFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDG 217 RFSP VS D + ++W+ + K L GH G V V SPDG + + DG Sbjct: 1554 RFSPEGNLIATVSA--DHTARLWDRSG-KTVAVLYGHQGLVGTVDWSPDGQMLVTASNDG 1610 Query: 218 VTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQD-SIKIWDLES 364 LWDL+ G+ L +L+ G+ + S FSP+ W+ ++ D + K+W +++ Sbjct: 1611 TARLWDLS-GRELLTLEGHGNWVRSAEFSPDGRWVLTSSADGTAKLWPVKT 1660 Score = 50.1 bits (118), Expect = 4e-06 Identities = 41/169 (24%), Positives = 77/169 (45%), Gaps = 2/169 (1%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G + WV F+P +++ S D++ ++W T + L H G+V SPDG Sbjct: 1340 GHSHWVRNAHFNPKG--DRLLTVSRDKTARLWT-TEGECVAVLADHQGWVREGQFSPDGQ 1396 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQD-SIKIWDLES 364 +G D LW++ GK+L L + ++ FSP+ ++ A++D + ++W+ Sbjct: 1397 WIVTGSADKTAQLWNVL-GKKLTVLRGHQDAVLNVRFSPDSQYIVTASKDGTARVWNNTG 1455 Query: 365 KHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISG 511 + + E + + + +SADG + D T I++I G Sbjct: 1456 RELAVLRHYEKNIFAAE--------FSADGQFIVTASDDNTAGIWEIVG 1496 Score = 49.3 bits (116), Expect = 7e-06 Identities = 40/167 (23%), Positives = 72/167 (43%), Gaps = 1/167 (0%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG 187 RG G V +FS ++ I++ S D + ++W+ L TL GH V SP+G Sbjct: 1503 RGHEGPVYFAQFSADS--RYILTASVDNTARIWDFLGRPL-LTLAGHQSIVYQARFSPEG 1559 Query: 188 SLCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLES 364 +L A+ D LWD + ++ ++ +SP+ L A+ D + ++WDL Sbjct: 1560 NLIATVSADHTARLWDRSGKTVAVLYGHQGLVGTVDWSPDGQMLVTASNDGTARLWDLSG 1619 Query: 365 KHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 + E+ + +S DG + DGT +++ + Sbjct: 1620 R--------ELLTLEGHGNWVRSAEFSPDGRWVLTSSADGTAKLWPV 1658 Score = 47.0 bits (110), Expect = 4e-05 Identities = 28/84 (33%), Positives = 44/84 (52%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G G V V +SP+ +V+ S D + ++W+L+ +L TL+GHG +V + SPDG Sbjct: 1586 GHQGLVGTVDWSPDG--QMLVTASNDGTARLWDLSGREL-LTLEGHGNWVRSAEFSPDGR 1642 Query: 191 LCASGGKDGVTLLWDLTEGKRLYS 262 + DG LW + +L S Sbjct: 1643 WVLTSSADGTAKLWPVKTLPQLLS 1666 Score = 47.0 bits (110), Expect = 4e-05 Identities = 38/149 (25%), Positives = 58/149 (38%), Gaps = 1/149 (0%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 IV+ S D + +W + ++ GH G V S D + D +WD Sbjct: 1480 IVTASDDNTAGIWEIVGREVGICR-GHEGPVYFAQFSADSRYILTASVDNTARIWDFLGR 1538 Query: 248 KRLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQDLRPEVPVSSKQMLY 424 L SI+ FSP + + D + ++WD K + + Q L Sbjct: 1539 PLLTLAGHQSIVYQARFSPEGNLIATVSADHTARLWDRSGKTVAV-------LYGHQGLV 1591 Query: 425 CTCLSWSADGSTLYAGYTDGTIRIYKISG 511 T + WS DG L DGT R++ +SG Sbjct: 1592 GT-VDWSPDGQMLVTASNDGTARLWDLSG 1619 Score = 45.1 bits (105), Expect = 1e-04 Identities = 35/146 (23%), Positives = 62/146 (42%), Gaps = 1/146 (0%) Frame = +2 Query: 74 SGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLT-EGK 250 + S D +VK+W ++ TL GH +V +V SP + G+D +W+ E Sbjct: 1072 TASADHTVKLWQRHGEEV-ATLRGHEDWVRSVHFSPHHQFLVTSGQDNTARIWNFAGEQL 1130 Query: 251 RLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCT 430 L A + N+ + L A+ + ++WDLE + E+ + + Sbjct: 1131 TLCQGHADWVRNAEFNCHGQILLTASRDGTARLWDLEGR--------EIGLCQGHTSWVR 1182 Query: 431 CLSWSADGSTLYAGYTDGTIRIYKIS 508 +S DG + DGT R++ +S Sbjct: 1183 NAQFSPDGQWIVTCSADGTARLWDLS 1208 Score = 42.7 bits (99), Expect = 7e-04 Identities = 36/169 (21%), Positives = 68/169 (40%), Gaps = 1/169 (0%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG 187 +G WV F N +++ S D + ++W+L ++ GH +V SPDG Sbjct: 1134 QGHADWVRNAEF--NCHGQILLTASRDGTARLWDLEGREIGLC-QGHTSWVRNAQFSPDG 1190 Query: 188 SLCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLES 364 + DG LWDL+ + +N+ +SP+ + ++ D + ++W Sbjct: 1191 QWIVTCSADGTARLWDLSSQCFAVLKGHQNWVNNALWSPDGQHIITSSSDGTARVWSRHG 1250 Query: 365 KHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISG 511 K + + + + +S DG + TD T R++ G Sbjct: 1251 KCLGTLRGHDHNIHGAR--------FSLDGQKIVTYSTDNTARLWTKEG 1291 Score = 41.2 bits (95), Expect = 0.002 Identities = 38/168 (22%), Positives = 74/168 (44%), Gaps = 4/168 (2%) Frame = +2 Query: 20 GWVSCVRFSPN--NFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSL 193 G V+ +R SP+ N P +++ + + +W+ +L L GH ++A+ S DG Sbjct: 1011 GPVTVLRISPSMENTPPLVLTATTNGIAYLWSFHG-ELINVLRGHQEAITALDWSADGQY 1069 Query: 194 CASGGKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQD-SIKIWDLESK 367 A+ D LW G+ + +L + S+ FSP+ +L + QD + +IW+ + Sbjct: 1070 FATASADHTVKLWQ-RHGEEVATLRGHEDWVRSVHFSPHHQFLVTSGQDNTARIWNFAGE 1128 Query: 368 HIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISG 511 ++ + + ++ G L DGT R++ + G Sbjct: 1129 --------QLTLCQGHADWVRNAEFNCHGQILLTASRDGTARLWDLEG 1168 Score = 38.5 bits (88), Expect = 0.013 Identities = 34/146 (23%), Positives = 64/146 (43%), Gaps = 2/146 (1%) Frame = +2 Query: 80 SWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLY 259 S D++ + W+++ K TL GH +V +P G + +D LW TEG+ + Sbjct: 1320 SADQTARQWDISQ-KDTITLTGHSHWVRNAHFNPKGDRLLTVSRDKTARLW-TTEGECVA 1377 Query: 260 SL-DAGSIINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQDLRPEVPVSSKQMLYCTC 433 L D + FSP+ W+ + D + ++W++ K + + V + Sbjct: 1378 VLADHQGWVREGQFSPDGQWIVTGSADKTAQLWNVLGKKLTVLRGHQDAVLN-------- 1429 Query: 434 LSWSADGSTLYAGYTDGTIRIYKISG 511 + +S D + DGT R++ +G Sbjct: 1430 VRFSPDSQYIVTASKDGTARVWNNTG 1455
>WSB2_MOUSE (O54929) WD repeat and SOCS box-containing protein 2 (WSB-2) (SOCS| box-containing WD protein SWiP-2) Length = 404 Score = 65.9 bits (159), Expect = 8e-11 Identities = 48/177 (27%), Positives = 75/177 (42%), Gaps = 14/177 (7%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G WV C SP+ + S + ++SV +W++ + L L+GH V + SPD + Sbjct: 195 GHLQWVYCCSISPD--CSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCDFSPDSA 252 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAG-------------SIINSLCFSPNRYWLCAAT 331 L + D ++WD G RL SL S + S+CFSP +L Sbjct: 253 LLVTASYDTSVIMWDPYTGARLRSLHHTQLEPTMDDSDVHMSSLRSVCFSPEGLYLATVA 312 Query: 332 QDS-IKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 D ++IW LE K PV+ M C ++ G + G DG ++ + Sbjct: 313 DDRLLRIWALELK---------APVAFAPMTNGLCCTFFPHGGIIATGTRDGHVQFW 360 Score = 46.6 bits (109), Expect = 5e-05 Identities = 30/110 (27%), Positives = 53/110 (48%), Gaps = 4/110 (3%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSL-CASGGKDGVTLLWDLTE 244 + +G D +K+W + L L GH V ++ +P GSL S +D +WDL + Sbjct: 126 LATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNK 185 Query: 245 GKRLYSLDAGSIINSLC--FSPNRYWLC-AATQDSIKIWDLESKHIVQDL 385 + + +G + C SP+ LC AA + S+ +W + S +++ L Sbjct: 186 HGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKL 235
>PRP46_ASPFU (Q4WT34) Pre-mRNA-splicing factor prp46 (Pre-mRNA-processing| protein 46) Length = 453 Score = 65.9 bits (159), Expect = 8e-11 Identities = 48/168 (28%), Positives = 72/168 (42%), Gaps = 2/168 (1%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G GWV + PNN SG+ DR++K+WNL LR TL GH V +AVSP Sbjct: 142 GHLGWVRSLAVEPNN--EWFASGAGDRTIKIWNLATGALRLTLTGHISTVRGLAVSPRHP 199 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAG-SIINSLCFSPNRYWLCAATQDSI-KIWDLES 364 S G+D + WDL K + S + +L P L +D + ++WD+ + Sbjct: 200 YLFSCGEDKMVKCWDLETNKVIRHYHGHLSGVYTLALHPRLDLLVTGGRDGVARVWDMRT 259 Query: 365 KHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 R + V S L + G D T+R++ ++ Sbjct: 260 -------RSNIHVLSGHKGTVADLKCQEADPQIITGSLDATVRLWDLA 300 Score = 50.1 bits (118), Expect = 4e-06 Identities = 29/88 (32%), Positives = 45/88 (51%), Gaps = 2/88 (2%) Frame = +2 Query: 122 KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGK-RLYSLDAGSIINSLCF 298 KL + GH G+V ++AV P+ ASG D +W+L G RL S + L Sbjct: 135 KLMRVISGHLGWVRSLAVEPNNEWFASGAGDRTIKIWNLATGALRLTLTGHISTVRGLAV 194 Query: 299 SPNRYWLCAATQDS-IKIWDLESKHIVQ 379 SP +L + +D +K WDLE+ +++ Sbjct: 195 SPRHPYLFSCGEDKMVKCWDLETNKVIR 222 Score = 42.0 bits (97), Expect = 0.001 Identities = 27/106 (25%), Positives = 43/106 (40%), Gaps = 1/106 (0%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 +V+G D +VW++ L GH G V+ + +G D LWDL G Sbjct: 243 LVTGGRDGVARVWDMRTRSNIHVLSGHKGTVADLKCQEADPQIITGSLDATVRLWDLAAG 302 Query: 248 KRLYSLDAGSI-INSLCFSPNRYWLCAATQDSIKIWDLESKHIVQD 382 K + L + +L P + +A+ SIK W +Q+ Sbjct: 303 KTMGVLTHHKKGVRNLAIHPREFTFASASTGSIKQWKCPEGDFMQN 348 Score = 37.0 bits (84), Expect = 0.038 Identities = 28/97 (28%), Positives = 40/97 (41%), Gaps = 10/97 (10%) Frame = +2 Query: 92 SVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLY---- 259 S+K W +GH ++++AV+ D L SGG +G WD G + Sbjct: 334 SIKQWKCPEGDFMQNFEGHNAVINSLAVNEDNVL-FSGGDNGSMCFWDWKTGYKFQSIDT 392 Query: 260 -----SLDAGSIINSLCFSPNRYWLCAATQD-SIKIW 352 SLDA + I S F L D +IK+W Sbjct: 393 MAQPGSLDAEAGIMSATFDRTGLRLITGEADKTIKVW 429
>TUP1_YEAST (P16649) Glucose repression regulatory protein TUP1 (Flocculation| suppressor protein) (Repressor AER2) Length = 713 Score = 65.5 bits (158), Expect = 1e-10 Identities = 39/172 (22%), Positives = 83/172 (48%), Gaps = 4/172 (2%) Frame = +2 Query: 23 WVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCAS 202 ++ V FSP+ + +G+ DR +++W++ N K+ L GH + ++ P G S Sbjct: 445 YIRSVCFSPDG--KFLATGAEDRLIRIWDIENRKIVMILQGHEQDIYSLDYFPSGDKLVS 502 Query: 203 GGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSP--NRYWLCAATQDSIKIWDLESKHIV 376 G D +WDL G+ +L + ++ SP +Y + ++++WD E+ +V Sbjct: 503 GSGDRTVRIWDLRTGQCSLTLSIEDGVTTVAVSPGDGKYIAAGSLDRAVRVWDSETGFLV 562 Query: 377 Q--DLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISGFSYSS 526 + D E K +Y + ++ DG ++ +G D +++++ + + S Sbjct: 563 ERLDSENESGTGHKDSVY--SVVFTRDGQSVVSGSLDRSVKLWNLQNANNKS 612 Score = 48.1 bits (113), Expect = 2e-05 Identities = 29/79 (36%), Positives = 37/79 (46%), Gaps = 12/79 (15%) Frame = +2 Query: 65 TIVSGSWDRSVKVWNLTNCKLRC------------TLDGHGGYVSAVAVSPDGSLCASGG 208 ++VSGS DRSVK+WNL N + T GH +V +VA + + SG Sbjct: 590 SVVSGSLDRSVKLWNLQNANNKSDSKTPNSGTCEVTYIGHKDFVLSVATTQNDEYILSGS 649 Query: 209 KDGVTLLWDLTEGKRLYSL 265 KD L WD G L L Sbjct: 650 KDRGVLFWDKKSGNPLLML 668 Score = 30.8 bits (68), Expect = 2.7 Identities = 20/61 (32%), Positives = 30/61 (49%), Gaps = 6/61 (9%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVS------PDGSLCASGGKDGVTLL 229 I+SGS DR V W+ + L GH V +VAV+ P+ ++ A+G D + Sbjct: 645 ILSGSKDRGVLFWDKKSGNPLLMLQGHRNSVISVAVANGSPLGPEYNVFATGSGDCKARI 704 Query: 230 W 232 W Sbjct: 705 W 705
>PRP46_SCHPO (O13615) Pre-mRNA-splicing factor prp46 (Pre-mRNA-processing| protein 5) (Complexed with cdc5 protein 1) Length = 473 Score = 65.5 bits (158), Expect = 1e-10 Identities = 49/168 (29%), Positives = 76/168 (45%), Gaps = 2/168 (1%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G GWV CV P N +G+ DR++K+W+L + L+ TL GH V +AVSP Sbjct: 161 GHLGWVRCVDVEPGN--QWFCTGAGDRTIKIWDLASGVLKLTLTGHIATVRGLAVSPRHP 218 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAG-SIINSLCFSPNRYWLCAATQDSI-KIWDLES 364 S G+D + WDL K + S + +L P L A +D++ ++WD+ + Sbjct: 219 YLFSCGEDKMVKCWDLETNKVIRHYHGHLSGVYALKLHPTLDVLVTAGRDAVARVWDMRT 278 Query: 365 KHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 R V V S L+ + G D TIR++ ++ Sbjct: 279 -------RQNVHVLSGHKSTVASLAVQEFDPQVVTGSMDSTIRLWDLA 319 Score = 63.9 bits (154), Expect = 3e-10 Identities = 44/151 (29%), Positives = 71/151 (47%), Gaps = 2/151 (1%) Frame = +2 Query: 56 FAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWD 235 F P +V+GS D ++++W+L K TL H V A+++ PD ASG D + W Sbjct: 300 FDPQVVTGSMDSTIRLWDLAAGKTLTTLTHHKKTVRALSLHPDEFTFASGSSDNIK-HWK 358 Query: 236 LTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEV-PVSS 409 EG + + + +I+N+L + + A S+ WD +S H Q+L+ V P S Sbjct: 359 FPEGAFMGNFEGHNAIVNTLSINSDNVMFSGADNGSMCFWDWKSGHKYQELQSVVQPGSL 418 Query: 410 KQMLYCTCLSWSADGSTLYAGYTDGTIRIYK 502 S+ G L D +++IYK Sbjct: 419 DSEAGIFASSFDKTGLRLITCEADKSVKIYK 449 Score = 46.2 bits (108), Expect = 6e-05 Identities = 26/96 (27%), Positives = 44/96 (45%), Gaps = 1/96 (1%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 +V+ D +VW++ + L GH V+++AV +G D LWDL G Sbjct: 262 LVTAGRDAVARVWDMRTRQNVHVLSGHKSTVASLAVQEFDPQVVTGSMDSTIRLWDLAAG 321 Query: 248 KRLYSL-DAGSIINSLCFSPNRYWLCAATQDSIKIW 352 K L +L + +L P+ + + + D+IK W Sbjct: 322 KTLTTLTHHKKTVRALSLHPDEFTFASGSSDNIKHW 357 Score = 43.9 bits (102), Expect = 3e-04 Identities = 24/83 (28%), Positives = 39/83 (46%), Gaps = 2/83 (2%) Frame = +2 Query: 137 LDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLDAG-SIINSLCFSPNRY 313 + GH G+V V V P +G D +WDL G +L + + L SP Sbjct: 159 ISGHLGWVRCVDVEPGNQWFCTGAGDRTIKIWDLASGVLKLTLTGHIATVRGLAVSPRHP 218 Query: 314 WLCAATQDS-IKIWDLESKHIVQ 379 +L + +D +K WDLE+ +++ Sbjct: 219 YLFSCGEDKMVKCWDLETNKVIR 241
>YCW2_YEAST (P25382) Hypothetical WD-repeat protein YCR072C| Length = 515 Score = 65.5 bits (158), Expect = 1e-10 Identities = 49/171 (28%), Positives = 82/171 (47%), Gaps = 10/171 (5%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 + C F+P+ + +V+G+ D + ++W+ TL GH +V V+ SPDG + A+G Sbjct: 146 ILCSAFAPHT-SSRMVTGAGDNTARIWDCDTQTPMHTLKGHYNWVLCVSWSPDGEVIATG 204 Query: 206 GKDGVTLLWDLTEGKRLYSLDAG--SIINSLCFSP-------NRYWLCAATQD-SIKIWD 355 D LWD G+ L G I SL + P ++ L ++++D +IKIWD Sbjct: 205 SMDNTIRLWDPKSGQCLGDALRGHSKWITSLSWEPIHLVKPGSKPRLASSSKDGTIKIWD 264 Query: 356 LESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 S+ + S +C+ W G LY+G D T+R++ I+ Sbjct: 265 TVSRVCQYTM-------SGHTNSVSCVKWGGQG-LLYSGSHDRTVRVWDIN 307 Score = 55.8 bits (133), Expect = 8e-08 Identities = 41/152 (26%), Positives = 69/152 (45%), Gaps = 3/152 (1%) Frame = +2 Query: 53 NFAPTIVSGSWDRSVKVWN-LTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLL 229 N +V+ S D ++ +WN L + K + GH V+ VA SPDG S D L Sbjct: 369 NSEEMMVTASDDYTMFLWNPLKSTKPIARMTGHQKLVNHVAFSPDGRYIVSASFDNSIKL 428 Query: 230 WDLTEGKRLYSL--DAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPV 403 WD +GK + + S+ S R + + ++K+WD+ ++ + DL Sbjct: 429 WDGRDGKFISTFRGHVASVYQVAWSSDCRLLVSCSKDTTLKVWDVRTRKLSVDL-----P 483 Query: 404 SSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 K +Y + WS DG + +G D +R++ Sbjct: 484 GHKDEVY--TVDWSVDGKRVCSGGKDKMVRLW 513 Score = 47.8 bits (112), Expect = 2e-05 Identities = 49/209 (23%), Positives = 86/209 (41%), Gaps = 44/209 (21%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRC--TLDGHGGYVSAVAVSPD 184 G T VSCV++ + SGS DR+V+VW++ N + RC L H +V+ +++S D Sbjct: 276 GHTNSVSCVKWGGQGL---LYSGSHDRTVRVWDI-NSQGRCINILKSHAHWVNHLSLSTD 331 Query: 185 GSL-----------------------------CASGGK----------DGVTLLWDLTEG 247 +L C G D LW+ + Sbjct: 332 YALRIGAFDHTGKKPSTPEEAQKKALENYEKICKKNGNSEEMMVTASDDYTMFLWNPLKS 391 Query: 248 KRLYSLDAG--SIINSLCFSPN-RYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQM 418 + + G ++N + FSP+ RY + A+ +SIK+WD + R V + Sbjct: 392 TKPIARMTGHQKLVNHVAFSPDGRYIVSASFDNSIKLWDGRDGKFISTFRGHVASVYQ-- 449 Query: 419 LYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 ++WS+D L + D T++++ + Sbjct: 450 -----VAWSSDCRLLVSCSKDTTLKVWDV 473 Score = 45.4 bits (106), Expect = 1e-04 Identities = 33/129 (25%), Positives = 63/129 (48%), Gaps = 9/129 (6%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCK-LRCTLDGHGGYVSAVAVSP- 181 +G WV CV +SP+ I +GS D ++++W+ + + L L GH ++++++ P Sbjct: 183 KGHYNWVLCVSWSPD--GEVIATGSMDNTIRLWDPKSGQCLGDALRGHSKWITSLSWEPI 240 Query: 182 ----DGS--LCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQD-S 340 GS AS KDG +WD Y++ + S + L + + D + Sbjct: 241 HLVKPGSKPRLASSSKDGTIKIWDTVSRVCQYTMSGHTNSVSCVKWGGQGLLYSGSHDRT 300 Query: 341 IKIWDLESK 367 +++WD+ S+ Sbjct: 301 VRVWDINSQ 309 Score = 43.5 bits (101), Expect = 4e-04 Identities = 29/75 (38%), Positives = 38/75 (50%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 V+ V FSP+ IVS S+D S+K+W+ + K T GH V VA S D L S Sbjct: 405 VNHVAFSPDG--RYIVSASFDNSIKLWDGRDGKFISTFRGHVASVYQVAWSSDCRLLVSC 462 Query: 206 GKDGVTLLWDLTEGK 250 KD +WD+ K Sbjct: 463 SKDTTLKVWDVRTRK 477
>PWP2_SCHPO (Q9C1X1) Periodic tryptophan protein 2 homolog| Length = 854 Score = 65.5 bits (158), Expect = 1e-10 Identities = 46/151 (30%), Positives = 76/151 (50%), Gaps = 5/151 (3%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 I++G+ D +KVW++ + T H VS + S G++ S DG WDL Sbjct: 354 IITGADDGKIKVWDMNSGFCIVTFTQHTSAVSGLCFSKRGNVLFSSSLDGSVRAWDLIRY 413 Query: 248 KRLYSLDAGSIINSLCFS--PNRYWLCAATQDSIKI--WDLESKHIVQDLR-PEVPVSSK 412 + + A S + C + P+ +CA +QDS +I W +++ +++ L E PVSS Sbjct: 414 RNFRTFTAPSRVQFSCIAVDPSGEIVCAGSQDSFEIFMWSVQTGQLLETLAGHEGPVSS- 472 Query: 413 QMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 LS+++ GS L +G D T+RI+ I Sbjct: 473 -------LSFNSSGSLLASGSWDKTVRIWDI 496 Score = 40.8 bits (94), Expect = 0.003 Identities = 25/86 (29%), Positives = 41/86 (47%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G G VS + F N+ + SGSWD++V++W++ + V ++A PDG Sbjct: 465 GHEGPVSSLSF--NSSGSLLASGSWDKTVRIWDIFSRSGIVEPLPIPSDVLSLAFHPDGK 522 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLD 268 DG W++ EGK+ +D Sbjct: 523 EVCVASLDGQLTFWNVQEGKQTSLID 548 Score = 38.9 bits (89), Expect = 0.010 Identities = 38/158 (24%), Positives = 71/158 (44%), Gaps = 3/158 (1%) Frame = +2 Query: 41 FSPNNFAPTIVSGSWDRSVKVWNLT-NCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDG 217 F+P+ F+ I+S +R V V+NL N + H +S +A+SP +L S ++G Sbjct: 22 FTPDGFS--ILSPVGNR-VSVYNLKDNTSYTFPFENHKN-ISHIALSPTSTLLLSVDEEG 77 Query: 218 VTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEV 397 +L + L+ + S + ++ FSPN + + I++W + ++ P V Sbjct: 78 RCILCNFLRRSVLHYFNFKSPVGAIEFSPNGKFFAVSLGKLIQVWRTPNSLEEREFAPFV 137 Query: 398 PVSSKQMLY--CTCLSWSADGSTLYAGYTDGTIRIYKI 505 + +SWSAD + D T R++ + Sbjct: 138 LHREYTGHFDDIVSISWSADSRFFISTSKDLTARLHSV 175
>TAF5_HUMAN (Q15542) Transcription initiation factor TFIID subunit 5| (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100) Length = 800 Score = 65.1 bits (157), Expect = 1e-10 Identities = 37/112 (33%), Positives = 62/112 (55%), Gaps = 2/112 (1%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 V+C RF PN+ + +GS DR+V++W++ N GH G + ++ SP+G A+G Sbjct: 630 VNCTRFHPNS--NYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATG 687 Query: 206 GKDGVTLLWDLTEGKRLYSLDAGS-IINSLCFSPNRYWLCAATQD-SIKIWD 355 DG LLWD+ G + L + + SL FS + L + + D ++++WD Sbjct: 688 ATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWD 739 Score = 61.2 bits (147), Expect = 2e-09 Identities = 46/157 (29%), Positives = 74/157 (47%), Gaps = 3/157 (1%) Frame = +2 Query: 38 RFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDG 217 +FSP + VSG DR ++W + + GH V+ P+ + A+G D Sbjct: 592 QFSPYGYY--FVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADR 649 Query: 218 VTLLWDLTEGK--RLYSLDAGSIINSLCFSPN-RYWLCAATQDSIKIWDLESKHIVQDLR 388 LWD+ G R+++ G I+SL FSPN R+ AT + +WD+ +V +L+ Sbjct: 650 TVRLWDVLNGNCVRIFTGHKGP-IHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELK 708 Query: 389 PEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 C+ L +S DG L +G D T+R++ Sbjct: 709 GHTDT------VCS-LRFSRDGEILASGSMDNTVRLW 738 Score = 52.0 bits (123), Expect = 1e-06 Identities = 47/169 (27%), Positives = 79/169 (46%), Gaps = 4/169 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G +G V FSP+ ++S S D +V++W+L GH V SP G Sbjct: 541 GHSGPVYGASFSPDR--NYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGY 598 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSI--INSLCFSPNRYWLCAATQD-SIKIWDLE 361 SGG D V LW T+ + + AG + +N F PN ++ + D ++++WD+ Sbjct: 599 YFVSGGHDRVARLW-ATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVL 657 Query: 362 SKHIVQDLR-PEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 + + V+ + P+ S L++S +G L G TDG + ++ I Sbjct: 658 NGNCVRIFTGHKGPIHS--------LTFSPNGRFLATGATDGRVLLWDI 698 Score = 37.7 bits (86), Expect = 0.022 Identities = 39/179 (21%), Positives = 65/179 (36%), Gaps = 33/179 (18%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCT-------------------------------LDGHGG 154 I G D +V+VW++T KLR L GH G Sbjct: 485 IAGGFADSTVRVWSVTPKKLRSVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHSG 544 Query: 155 YVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLDAGSI-INSLCFSPNRYWLCAAT 331 V + SPD + S +DG LW L L + + FSP Y+ + Sbjct: 545 PVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGG 604 Query: 332 QDSI-KIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 D + ++W + Q LR + + + C + + + + G D T+R++ + Sbjct: 605 HDRVARLWATDH---YQPLR----IFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDV 656
>BRWD1_MOUSE (Q921C3) Bromodomain and WD-repeat domain-containing protein 1| (WD-repeat protein 9) Length = 2304 Score = 65.1 bits (157), Expect = 1e-10 Identities = 55/168 (32%), Positives = 76/168 (45%), Gaps = 10/168 (5%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 V CV F I +GS D VK+W+ N +L TL GH +S +AV+ + +L A+G Sbjct: 189 VYCVAFDRTGHR--IFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTLIAAG 246 Query: 206 GKDGVTLLWDLTEGKRLYSLDAGS-IINSLCFS-----PNRYWLCAATQDSIKIWDLESK 367 D V +W L + L + I SL FS P RY + ++ W + + Sbjct: 247 SCDKVIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGPQRYMVSTGADGTVCFWQWDLE 306 Query: 368 HIVQDLRP----EVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 + RP E P QML C S+S G L G TD IR+Y Sbjct: 307 SLKFSPRPLKFTEKPRPGVQML---CSSFSVGGMFLATGSTDHVIRMY 351 Score = 39.3 bits (90), Expect = 0.008 Identities = 21/65 (32%), Positives = 33/65 (50%), Gaps = 1/65 (1%) Frame = +2 Query: 65 TIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSP-DGSLCASGGKDGVTLLWDLT 241 T+V+ D +KVW+ +L L GH V + P D + S G DG +WD+T Sbjct: 440 TVVTAVNDHVLKVWSSYTGQLLHNLLGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDIT 499 Query: 242 EGKRL 256 +G ++ Sbjct: 500 KGIKM 504
>GBB_LYMST (Q08706) Guanine nucleotide-binding protein beta subunit| Length = 341 Score = 64.7 bits (156), Expect = 2e-10 Identities = 46/170 (27%), Positives = 83/170 (48%), Gaps = 5/170 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G TG++SC RF +N +IV+ S D S +W++ + + GH G V +++ SPD Sbjct: 142 GHTGYLSCCRFIDDN---SIVTSSGDMSCALWDIETGQQTTSFTGHTGDVMSLSTSPDFR 198 Query: 191 LCASGGKDGVTLLWDLTEG--KRLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLE 361 SG D LWD+ +G K+ +S S IN++ + PN + + D + +++D+ Sbjct: 199 TFVSGACDASAKLWDVRDGMCKQTFS-GHESDINAITYFPNGHAFATGSDDATCRLFDIR 257 Query: 362 SKHIVQDLRPEVPVSSKQMLYC--TCLSWSADGSTLYAGYTDGTIRIYKI 505 + E+ + S + C T +++S G L Y D ++ + Sbjct: 258 ADQ-------EIGMYSHDNIICGITSVAFSKSGRLLLGRYDDFNCNVWDV 300 Score = 54.3 bits (129), Expect = 2e-07 Identities = 44/170 (25%), Positives = 78/170 (45%), Gaps = 4/170 (2%) Frame = +2 Query: 2 SARGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSP 181 S G TG V + SP+ T VSG+ D S K+W++ + + T GH ++A+ P Sbjct: 180 SFTGHTGDVMSLSTSPD--FRTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFP 237 Query: 182 DGSLCASGGKDGVTLLWDLTEGKRLYSLDAGSI---INSLCFSPNRYWLCAATQD-SIKI 349 +G A+G D L+D+ + + +I I S+ FS + L D + + Sbjct: 238 NGHAFATGSDDATCRLFDIRADQEIGMYSHDNIICGITSVAFSKSGRLLLGRYDDFNCNV 297 Query: 350 WDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 WD+ + Q+ + ++ +CL + DGS + G D ++I+ Sbjct: 298 WDV----LKQETHGVLAGHDNRV---SCLGVTEDGSAVATGSWDSFLKIW 340 Score = 46.2 bits (108), Expect = 6e-05 Identities = 43/170 (25%), Positives = 71/170 (41%), Gaps = 7/170 (4%) Frame = +2 Query: 17 TGWVSCVRFSPN-NFAPTIVSGSWDRSVKVWNLT----NCKLRCTLDGHGGYVSAVAVSP 181 + WV ++P+ NF + G D +++L N ++ L GH GY+S Sbjct: 98 SSWVMTCAYAPSGNF---VACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFID 154 Query: 182 DGSLCASGGKDGVTLLWDLTEGKRLYSLDAGS-IINSLCFSPN-RYWLCAATQDSIKIWD 355 D S+ S G D LWD+ G++ S + + SL SP+ R ++ A S K+WD Sbjct: 155 DNSIVTSSG-DMSCALWDIETGQQTTSFTGHTGDVMSLSTSPDFRTFVSGACDASAKLWD 213 Query: 356 LESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 + Q S +++ +G G D T R++ I Sbjct: 214 VRDGMCKQTF-------SGHESDINAITYFPNGHAFATGSDDATCRLFDI 256 Score = 34.3 bits (77), Expect = 0.25 Identities = 16/50 (32%), Positives = 25/50 (50%) Frame = +2 Query: 86 DRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWD 235 D + VW++ + L GH VS + V+ DGS A+G D +W+ Sbjct: 292 DFNCNVWDVLKQETHGVLAGHDNRVSCLGVTEDGSAVATGSWDSFLKIWN 341
>PRP46_EMENI (Q5BE22) Pre-mRNA-splicing factor prp46 (Pre-mRNA-processing| protein 46) Length = 452 Score = 64.7 bits (156), Expect = 2e-10 Identities = 40/121 (33%), Positives = 58/121 (47%), Gaps = 2/121 (1%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G GWV + PNN SG+ DR++K+WNL LR TL GH V +AVSP Sbjct: 141 GHLGWVRSLAVEPNN--EWFASGAGDRTIKIWNLATGALRLTLTGHISTVRGLAVSPRHP 198 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAG-SIINSLCFSPNRYWLCAATQDSI-KIWDLES 364 S G+D + WDL K + S + +L P L +D + ++WD+ + Sbjct: 199 YLFSCGEDKMVKCWDLETNKVIRHYHGHLSGVYTLALHPRLDLLVTGGRDGVARVWDMRT 258 Query: 365 K 367 + Sbjct: 259 R 259 Score = 50.1 bits (118), Expect = 4e-06 Identities = 29/88 (32%), Positives = 45/88 (51%), Gaps = 2/88 (2%) Frame = +2 Query: 122 KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGK-RLYSLDAGSIINSLCF 298 KL + GH G+V ++AV P+ ASG D +W+L G RL S + L Sbjct: 134 KLMRVISGHLGWVRSLAVEPNNEWFASGAGDRTIKIWNLATGALRLTLTGHISTVRGLAV 193 Query: 299 SPNRYWLCAATQDS-IKIWDLESKHIVQ 379 SP +L + +D +K WDLE+ +++ Sbjct: 194 SPRHPYLFSCGEDKMVKCWDLETNKVIR 221 Score = 44.3 bits (103), Expect = 2e-04 Identities = 30/106 (28%), Positives = 43/106 (40%), Gaps = 1/106 (0%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 +V+G D +VW++ L GH G V+ V +G D LWDL G Sbjct: 242 LVTGGRDGVARVWDMRTRSNIHVLSGHTGTVADVQCQEADPQVITGSLDATVRLWDLAAG 301 Query: 248 KRLYSLDAGSI-INSLCFSPNRYWLCAATQDSIKIWDLESKHIVQD 382 K + L I SL P + +A+ SIK W +Q+ Sbjct: 302 KTMGVLTHHKKGIRSLATHPREFTFASASTGSIKQWKCPGGEFMQN 347 Score = 35.0 bits (79), Expect = 0.14 Identities = 19/67 (28%), Positives = 31/67 (46%) Frame = +2 Query: 92 SVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLDA 271 S+K W + +GH ++ ++V+ D L SGG +G WD G R ++D Sbjct: 333 SIKQWKCPGGEFMQNFEGHNAIINTLSVNEDNVL-FSGGDNGSMSFWDWKTGYRYQTIDT 391 Query: 272 GSIINSL 292 + SL Sbjct: 392 TAQPGSL 398
>PLRG1_MOUSE (Q922V4) Pleiotropic regulator 1| Length = 513 Score = 64.3 bits (155), Expect = 2e-10 Identities = 43/127 (33%), Positives = 60/127 (47%), Gaps = 2/127 (1%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G GWV C+ P N V+GS DR++K+W+L + KL+ +L GH V V VS Sbjct: 201 GHLGWVRCIAVEPGN--QWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSP 258 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAG-SIINSLCFSPNRYWLCAATQDS-IKIWDLES 364 S G+D WDL K + S + L P L ++DS +IWD+ + Sbjct: 259 YLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTLDVLVTCSRDSTARIWDVRT 318 Query: 365 KHIVQDL 385 K V L Sbjct: 319 KASVHTL 325 Score = 55.5 bits (132), Expect = 1e-07 Identities = 45/166 (27%), Positives = 74/166 (44%), Gaps = 2/166 (1%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G T V+ VR P I++GS D ++++W+L K R TL H V AV + P Sbjct: 327 GHTNAVATVRCQAAE--PQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPLLY 384 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQDSIKIWDLESK 367 ASG D + W +G + +L +IIN+L + + + A ++ +WD + Sbjct: 385 TFASGSPDNIK-QWKFPDGGFIQNLSGHNAIINTLAVNADGVLVSGADNGTMHLWDWRTG 443 Query: 368 HIVQDLRPEV-PVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYK 502 + Q + V P S ++ S L D TI++Y+ Sbjct: 444 YNFQRVHAAVQPGSLDSESGIFACAFDRSESRLLTAEADKTIKVYR 489 Score = 47.8 bits (112), Expect = 2e-05 Identities = 30/109 (27%), Positives = 48/109 (44%), Gaps = 2/109 (1%) Frame = +2 Query: 59 APTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL 238 APT+ W K++ + + GH G+V +AV P +G D +WDL Sbjct: 181 APTMPKPQWHPPWKLYRV--------ISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDL 232 Query: 239 TEGKRLYSLDAG-SIINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQ 379 GK SL S + + S +L + +D +K WDLE +++ Sbjct: 233 ASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIR 281 Score = 46.6 bits (109), Expect = 5e-05 Identities = 36/145 (24%), Positives = 62/145 (42%), Gaps = 1/145 (0%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 +V+ S D + ++W++ TL GH V+ V +G D LWDL G Sbjct: 302 LVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAG 361 Query: 248 K-RLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLY 424 K R+ + + ++ P Y + + D+IK W +Q+L S Sbjct: 362 KTRVTLTNHKKSVRAVVLHPLLYTFASGSPDNIKQWKFPDGGFIQNL-------SGHNAI 414 Query: 425 CTCLSWSADGSTLYAGYTDGTIRIY 499 L+ +ADG L +G +GT+ ++ Sbjct: 415 INTLAVNADG-VLVSGADNGTMHLW 438
>TAF5_YEAST (P38129) Transcription initiation factor TFIID subunit 5| (TBP-associated factor 5) (TBP-associated factor 90 kDa) (TAFII-90) Length = 798 Score = 63.9 bits (154), Expect = 3e-10 Identities = 41/129 (31%), Positives = 68/129 (52%), Gaps = 4/129 (3%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNL-TNCKLRCTLDGHGGYVSAVAVSPDGSLCAS 202 V CV F PN + +GS D++ ++W++ T +R L GH V ++AV PDG ++ Sbjct: 612 VDCVSFHPNGCY--VFTGSSDKTCRMWDVSTGDSVRLFL-GHTAPVISIAVCPDGRWLST 668 Query: 203 GGKDGVTLLWDLTEGKRLYSL--DAGSIINSLCFSPNRYWLCAATQD-SIKIWDLESKHI 373 G +DG+ +WD+ GKRL + + I SL +S L + D ++++WDL+ Sbjct: 669 GSEDGIINVWDIGTGKRLKQMRGHGKNAIYSLSYSKEGNVLISGGADHTVRVWDLKKATT 728 Query: 374 VQDLRPEVP 400 P+ P Sbjct: 729 EPSAEPDEP 737 Score = 53.9 bits (128), Expect = 3e-07 Identities = 49/210 (23%), Positives = 87/210 (41%), Gaps = 45/210 (21%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGH------------GG 154 G +G V FSP+N ++SGS D++V++W++ + GH G Sbjct: 523 GHSGTVYSTSFSPDN--KYLLSGSEDKTVRLWSMDTHTALVSYKGHNHPVWDVSFSPLGH 580 Query: 155 Y------------------------------VSAVAVSPDGSLCASGGKDGVTLLWDLTE 244 Y V V+ P+G +G D +WD++ Sbjct: 581 YFATASHDQTARLWSCDHIYPLRIFAGHLNDVDCVSFHPNGCYVFTGSSDKTCRMWDVST 640 Query: 245 GK--RLYSLDAGSIINSLCFSPNRYWLCAATQDS-IKIWDLESKHIVQDLRPEVPVSSKQ 415 G RL+ +I S+ P+ WL ++D I +WD+ + ++ +R K Sbjct: 641 GDSVRLFLGHTAPVI-SIAVCPDGRWLSTGSEDGIINVWDIGTGKRLKQMRGH----GKN 695 Query: 416 MLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 +Y LS+S +G+ L +G D T+R++ + Sbjct: 696 AIY--SLSYSKEGNVLISGGADHTVRVWDL 723 Score = 49.7 bits (117), Expect = 6e-06 Identities = 43/180 (23%), Positives = 76/180 (42%), Gaps = 19/180 (10%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLR----------------C-TLDGHGG 154 +SC+ FS + +G D +K+W+L L C TL GH G Sbjct: 469 MSCLDFSDD--CRIAAAGFQDSYIKIWSLDGSSLNNPNIALNNNDKDEDPTCKTLVGHSG 526 Query: 155 YVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAAT 331 V + + SPD SG +D LW + L S + + FSP ++ A+ Sbjct: 527 TVYSTSFSPDNKYLLSGSEDKTVRLWSMDTHTALVSYKGHNHPVWDVSFSPLGHYFATAS 586 Query: 332 QD-SIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 D + ++W + HI + + + + C+S+ +G ++ G +D T R++ +S Sbjct: 587 HDQTARLWSCD--HIY-----PLRIFAGHLNDVDCVSFHPNGCYVFTGSSDKTCRMWDVS 639
>PLRG1_RAT (Q9WUC8) Pleiotropic regulator 1| Length = 514 Score = 63.9 bits (154), Expect = 3e-10 Identities = 43/127 (33%), Positives = 60/127 (47%), Gaps = 2/127 (1%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G GWV C+ P N V+GS DR++K+W+L + KL+ +L GH V V VS Sbjct: 202 GHLGWVRCIAVEPGN--QWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSP 259 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAG-SIINSLCFSPNRYWLCAATQDS-IKIWDLES 364 S G+D WDL K + S + L P L ++DS +IWD+ + Sbjct: 260 YLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRT 319 Query: 365 KHIVQDL 385 K V L Sbjct: 320 KASVHTL 326 Score = 56.2 bits (134), Expect = 6e-08 Identities = 45/166 (27%), Positives = 74/166 (44%), Gaps = 2/166 (1%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G T V+ VR P I++GS D ++++W+L K R TL H V AV + P Sbjct: 328 GHTNAVATVRCQAAE--PQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPLHY 385 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQDSIKIWDLESK 367 ASG D + W +G + +L +IIN+L + + + A ++ +WD + Sbjct: 386 TFASGSPDNIK-QWKFPDGGFIQNLSGHNAIINTLAVNTDGVLVSGADNGTMHLWDWRTG 444 Query: 368 HIVQDLRPEV-PVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYK 502 + Q + V P S ++ S L D TI++Y+ Sbjct: 445 YNFQRVHAAVQPGSLDSESGIFACAFDRSESRLLTAEADKTIKVYR 490 Score = 47.8 bits (112), Expect = 2e-05 Identities = 30/109 (27%), Positives = 48/109 (44%), Gaps = 2/109 (1%) Frame = +2 Query: 59 APTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL 238 APT+ W K++ + + GH G+V +AV P +G D +WDL Sbjct: 182 APTMPKPQWHPPWKLYRV--------ISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDL 233 Query: 239 TEGKRLYSLDAG-SIINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQ 379 GK SL S + + S +L + +D +K WDLE +++ Sbjct: 234 ASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIR 282 Score = 45.8 bits (107), Expect = 8e-05 Identities = 35/145 (24%), Positives = 61/145 (42%), Gaps = 1/145 (0%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 +V+ S D + ++W++ TL GH V+ V +G D LWDL G Sbjct: 303 LVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAG 362 Query: 248 K-RLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLY 424 K R+ + + ++ P Y + + D+IK W +Q+L S Sbjct: 363 KTRVTLTNHKKSVRAVVLHPLHYTFASGSPDNIKQWKFPDGGFIQNL-------SGHNAI 415 Query: 425 CTCLSWSADGSTLYAGYTDGTIRIY 499 L+ + DG L +G +GT+ ++ Sbjct: 416 INTLAVNTDG-VLVSGADNGTMHLW 439
>PLRG1_HUMAN (O43660) Pleiotropic regulator 1| Length = 514 Score = 63.9 bits (154), Expect = 3e-10 Identities = 43/127 (33%), Positives = 60/127 (47%), Gaps = 2/127 (1%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G GWV C+ P N V+GS DR++K+W+L + KL+ +L GH V V VS Sbjct: 202 GHLGWVRCIAVEPGN--QWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSP 259 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAG-SIINSLCFSPNRYWLCAATQDS-IKIWDLES 364 S G+D WDL K + S + L P L ++DS +IWD+ + Sbjct: 260 YLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRT 319 Query: 365 KHIVQDL 385 K V L Sbjct: 320 KASVHTL 326 Score = 57.4 bits (137), Expect = 3e-08 Identities = 45/166 (27%), Positives = 74/166 (44%), Gaps = 2/166 (1%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G T V+ VR P I++GS D ++++W+L K R TL H V AV + P Sbjct: 328 GHTNAVATVRCQAAE--PQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPRHY 385 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQDSIKIWDLESK 367 ASG D + W +G + +L +IIN+L + + + A ++ +WD + Sbjct: 386 TFASGSPDNIK-QWKFPDGSFIQNLSGHNAIINTLTVNSDGVLVSGADNGTMHLWDWRTG 444 Query: 368 HIVQDLRPEV-PVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYK 502 + Q + V P S ++ S L D TI++Y+ Sbjct: 445 YNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTAEADKTIKVYR 490 Score = 47.8 bits (112), Expect = 2e-05 Identities = 35/145 (24%), Positives = 62/145 (42%), Gaps = 1/145 (0%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 +V+ S D + ++W++ TL GH V+ V +G D LWDL G Sbjct: 303 LVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAG 362 Query: 248 K-RLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLY 424 K R+ + + ++ P Y + + D+IK W +Q+L S Sbjct: 363 KTRVTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQWKFPDGSFIQNL-------SGHNAI 415 Query: 425 CTCLSWSADGSTLYAGYTDGTIRIY 499 L+ ++DG L +G +GT+ ++ Sbjct: 416 INTLTVNSDG-VLVSGADNGTMHLW 439 Score = 47.8 bits (112), Expect = 2e-05 Identities = 30/109 (27%), Positives = 48/109 (44%), Gaps = 2/109 (1%) Frame = +2 Query: 59 APTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL 238 APT+ W K++ + + GH G+V +AV P +G D +WDL Sbjct: 182 APTMPKPQWHPPWKLYRV--------ISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDL 233 Query: 239 TEGKRLYSLDAG-SIINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQ 379 GK SL S + + S +L + +D +K WDLE +++ Sbjct: 234 ASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIR 282
>TAF5_MOUSE (Q8C092) Transcription initiation factor TFIID subunit 5| (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100) Length = 801 Score = 63.9 bits (154), Expect = 3e-10 Identities = 36/112 (32%), Positives = 62/112 (55%), Gaps = 2/112 (1%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 V+C R+ PN+ + +GS DR+V++W++ N GH G + ++ SP+G A+G Sbjct: 631 VNCTRYHPNS--NYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATG 688 Query: 206 GKDGVTLLWDLTEGKRLYSLDAGS-IINSLCFSPNRYWLCAATQD-SIKIWD 355 DG LLWD+ G + L + + SL FS + L + + D ++++WD Sbjct: 689 ATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWD 740 Score = 61.2 bits (147), Expect = 2e-09 Identities = 46/157 (29%), Positives = 74/157 (47%), Gaps = 3/157 (1%) Frame = +2 Query: 38 RFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDG 217 +FSP + VSG DR ++W + + GH V+ P+ + A+G D Sbjct: 593 QFSPYGYY--FVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRYHPNSNYVATGSADR 650 Query: 218 VTLLWDLTEGK--RLYSLDAGSIINSLCFSPN-RYWLCAATQDSIKIWDLESKHIVQDLR 388 LWD+ G R+++ G I+SL FSPN R+ AT + +WD+ +V +L+ Sbjct: 651 TVRLWDVLNGNCVRIFTGHKGP-IHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELK 709 Query: 389 PEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 C+ L +S DG L +G D T+R++ Sbjct: 710 GHTDT------VCS-LRFSRDGEILASGSMDNTVRLW 739 Score = 50.8 bits (120), Expect = 3e-06 Identities = 46/169 (27%), Positives = 79/169 (46%), Gaps = 4/169 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G +G V FSP+ ++S S D +V++W+L GH V SP G Sbjct: 542 GHSGPVYGASFSPDR--NYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGY 599 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSI--INSLCFSPNRYWLCAATQD-SIKIWDLE 361 SGG D V LW T+ + + AG + +N + PN ++ + D ++++WD+ Sbjct: 600 YFVSGGHDRVARLW-ATDHYQPLRIFAGHLADVNCTRYHPNSNYVATGSADRTVRLWDVL 658 Query: 362 SKHIVQDLR-PEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 + + V+ + P+ S L++S +G L G TDG + ++ I Sbjct: 659 NGNCVRIFTGHKGPIHS--------LTFSPNGRFLATGATDGRVLLWDI 699 Score = 38.1 bits (87), Expect = 0.017 Identities = 39/179 (21%), Positives = 65/179 (36%), Gaps = 33/179 (18%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCT-------------------------------LDGHGG 154 I G D +V+VW++T KLR L GH G Sbjct: 486 IAGGFADSTVRVWSVTPKKLRSVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHSG 545 Query: 155 YVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLDAGSI-INSLCFSPNRYWLCAAT 331 V + SPD + S +DG LW L L + + FSP Y+ + Sbjct: 546 PVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGG 605 Query: 332 QDSI-KIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 D + ++W + Q LR + + + C + + + + G D T+R++ + Sbjct: 606 HDRVARLWATDH---YQPLR----IFAGHLADVNCTRYHPNSNYVATGSADRTVRLWDV 657
>PWP2_YEAST (P25635) Periodic tryptophan protein 2 (U3 small nucleolar| RNA-associated protein 1) (U3 snoRNA-associated protein 1) Length = 923 Score = 63.9 bits (154), Expect = 3e-10 Identities = 47/155 (30%), Positives = 73/155 (47%), Gaps = 5/155 (3%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 +V+ S D +KVW++T+ T + H V+AV + G + S DG WDL Sbjct: 360 VVTASEDGKIKVWDITSGFCLATFEEHTSSVTAVQFAKRGQVMFSSSLDGTVRAWDLIRY 419 Query: 248 KRLYSLDAGSII--NSLCFSPNRYWLCAATQDS--IKIWDLESKHIVQDLR-PEVPVSSK 412 + + I N L P+ +CA + D+ I +W +++ ++ L E PVS Sbjct: 420 RNFRTFTGTERIQFNCLAVDPSGEVVCAGSLDNFDIHVWSVQTGQLLDALSGHEGPVS-- 477 Query: 413 QMLYCTCLSWSADGSTLYAGYTDGTIRIYKISGFS 517 CLS+S + S L + D TIRI+ I G S Sbjct: 478 ------CLSFSQENSVLASASWDKTIRIWSIFGRS 506 Score = 34.3 bits (77), Expect = 0.25 Identities = 35/157 (22%), Positives = 59/157 (37%), Gaps = 7/157 (4%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRC---TLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL 238 I++ S D S K+W++ + + T +GH YV S D + KDG +W+ Sbjct: 161 ILTTSKDLSAKIWSVDSEEKNLAATTFNGHRDYVMGAFFSHDQEKIYTVSKDGAVFVWEF 220 Query: 239 TEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKI----WDLESKHIVQDLRPEVPVS 406 T KR D + Q+ + I W + KH + +V Sbjct: 221 T--KRPSDDDDNESEDD------------DKQEEVDISKYSWRITKKHFFYANQAKV--- 263 Query: 407 SKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISGFS 517 C+++ L G+T G R+Y + F+ Sbjct: 264 -------KCVTFHPATRLLAVGFTSGEFRLYDLPDFT 293 Score = 32.3 bits (72), Expect = 0.94 Identities = 30/139 (21%), Positives = 59/139 (42%), Gaps = 2/139 (1%) Frame = +2 Query: 95 VKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLDAG 274 V V++L N K H ++A+ ++ G+L S +DG +L + L+ + Sbjct: 37 VSVFDLINNKSFTFEYEHRKNIAAIDLNKQGTLLISIDEDGRAILVNFKARNVLHHFNFK 96 Query: 275 SIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEV--PVSSKQMLYCTCLSWSA 448 +++ FSP+ A+ ++IW + + P V V + T L+WS Sbjct: 97 EKCSAVKFSPDGRLFALASGRFLQIWKTPDVNKDRQFAPFVRHRVHAGHFQDITSLTWSQ 156 Query: 449 DGSTLYAGYTDGTIRIYKI 505 D + D + +I+ + Sbjct: 157 DSRFILTTSKDLSAKIWSV 175
>GNB1L_HUMAN (Q9BYB4) Guanine nucleotide-binding protein beta subunit-like| protein 1 (G protein beta subunit-like protein 1) (WD40 repeat-containing protein deleted in VCFS) (WDVCF protein) (DGCRK3) Length = 327 Score = 63.9 bits (154), Expect = 3e-10 Identities = 51/168 (30%), Positives = 78/168 (46%), Gaps = 19/168 (11%) Frame = +2 Query: 62 PTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGY-VSAVAVSPDGSLCASGGKDGVTLLWDL 238 P + SGS V +W+L + TLDGHGG V+ + P G S G+D LWDL Sbjct: 38 PLLFSGSQSGLVHIWSLQTRRAVTTLDGHGGQCVTWLQTLPQGRQLLSQGRDLKLCLWDL 97 Query: 239 TEGKRLYSLDAGSIINSLCFSPNRY------------WLCAAT---QDSIKIWDLESKHI 373 EG+ ++++S+C + W A D ++I ++ SK Sbjct: 98 AEGR-------SAVVDSVCLESVGFCRSSILAGGQPRWTLAVPGRGSDEVQILEMPSKTS 150 Query: 374 VQDLRPEVPVSSKQMLYCTCLSWSADGST---LYAGYTDGTIRIYKIS 508 V L+P+ + M C L W AD S+ L AGY DG++ ++ +S Sbjct: 151 VCALKPKAD-AKLGMPMCLRL-WQADCSSRPLLLAGYEDGSVVLWDVS 196
>BRWD1_HUMAN (Q9NSI6) Bromodomain and WD-repeat domain-containing protein 1| (WD-repeat protein 9) Length = 2320 Score = 63.9 bits (154), Expect = 3e-10 Identities = 53/168 (31%), Positives = 76/168 (45%), Gaps = 10/168 (5%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 V CV F I +GS D VK+W+ N +L TL GH +S +AV+ + ++ A+G Sbjct: 189 VYCVAFDRTGHR--IFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAG 246 Query: 206 GKDGVTLLWDLTEGKRLYSLDAGS-IINSLCFSP-----NRYWLCAATQDSIKIWDLESK 367 D + +W L + L + I SL FSP RY + ++ W + + Sbjct: 247 SCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLE 306 Query: 368 HIVQDLRP----EVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 + RP E P QML C S+S G L G TD IR+Y Sbjct: 307 SLKFSPRPLKFTEKPRPGVQML---CSSFSVGGMFLATGSTDHVIRMY 351 Score = 40.4 bits (93), Expect = 0.003 Identities = 21/64 (32%), Positives = 32/64 (50%), Gaps = 1/64 (1%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSP-DGSLCASGGKDGVTLLWDLTE 244 +V+ D +KVWN +L L GH V + P D + S G DG +WD+T+ Sbjct: 441 VVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITK 500 Query: 245 GKRL 256 G ++ Sbjct: 501 GTKM 504
>GBB1_HOMAM (O45040) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 340 Score = 63.5 bits (153), Expect = 4e-10 Identities = 45/167 (26%), Positives = 80/167 (47%), Gaps = 4/167 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G TG++SC RF +N IV+ S D + +W++ + GH G V ++++SP+ Sbjct: 141 GHTGYLSCCRFVDDN---QIVTSSGDMTCALWDIETGQQCTQFTGHTGDVMSLSLSPNMR 197 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQD-SIKIWDLES 364 SG D LWD+ +G + S IN++ F PN + + D + +++D+ + Sbjct: 198 TFTSGACDASAKLWDIRDGMCRQTFPGHESDINAVTFFPNGHAFATGSDDATCRLFDIRA 257 Query: 365 KHIVQDLRPEVPVSSKQMLYC--TCLSWSADGSTLYAGYTDGTIRIY 499 E+ + S + C T +++S G L AGY D ++ Sbjct: 258 DQ-------ELAMYSHDNIICGITSVAFSKSGKLLLAGYDDFNCNVW 297 Score = 57.4 bits (137), Expect = 3e-08 Identities = 48/168 (28%), Positives = 74/168 (44%), Gaps = 5/168 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G TG V + SPN T SG+ D S K+W++ + R T GH ++AV P+G Sbjct: 182 GHTGDVMSLSLSPN--MRTFTSGACDASAKLWDIRDGMCRQTFPGHESDINAVTFFPNGH 239 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSI---INSLCFSPNRYWLCAATQD-SIKIWDL 358 A+G D L+D+ + L +I I S+ FS + L A D + +WD Sbjct: 240 AFATGSDDATCRLFDIRADQELAMYSHDNIICGITSVAFSKSGKLLLAGYDDFNCNVWD- 298 Query: 359 ESKHIVQDLRPE-VPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 +R E V + +CL + DG + G D ++I+ Sbjct: 299 -------SMRTERAGVLAGHDNRVSCLGVTEDGMAVATGSWDSFLKIW 339 Score = 45.1 bits (105), Expect = 1e-04 Identities = 41/170 (24%), Positives = 70/170 (41%), Gaps = 7/170 (4%) Frame = +2 Query: 17 TGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLT----NCKLRCTLDGHGGYVSAVAVSPD 184 + WV ++P+ + G D +++L N ++ L GH GY+S D Sbjct: 97 SSWVMTCAYAPSG--SYVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFVDD 154 Query: 185 GSLCASGGKDGVTLLWDLTEGKRL--YSLDAGSIINSLCFSPN-RYWLCAATQDSIKIWD 355 + S G D LWD+ G++ ++ G ++ SL SPN R + A S K+WD Sbjct: 155 NQIVTSSG-DMTCALWDIETGQQCTQFTGHTGDVM-SLSLSPNMRTFTSGACDASAKLWD 212 Query: 356 LESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 + R P + +++ +G G D T R++ I Sbjct: 213 IRDGM----CRQTFPGHESDI---NAVTFFPNGHAFATGSDDATCRLFDI 255 Score = 33.1 bits (74), Expect = 0.55 Identities = 19/70 (27%), Positives = 33/70 (47%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 ++ V FS + +++G D + VW+ + L GH VS + V+ DG A+G Sbjct: 273 ITSVAFSKSG--KLLLAGYDDFNCNVWDSMRTERAGVLAGHDNRVSCLGVTEDGMAVATG 330 Query: 206 GKDGVTLLWD 235 D +W+ Sbjct: 331 SWDSFLKIWN 340 Score = 29.6 bits (65), Expect = 6.1 Identities = 21/104 (20%), Positives = 46/104 (44%), Gaps = 2/104 (1%) Frame = +2 Query: 122 KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLD-AGSIINSLCF 298 + R TL GH + A+ D S +DG ++WD +++++ S + + + Sbjct: 46 RTRRTLRGHLAKIYAMHWGSDSRNLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAY 105 Query: 299 SPN-RYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYC 427 +P+ Y C + I+ L+++ + E+P + + C Sbjct: 106 APSGSYVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCC 149
>GBB1_CAEEL (P17343) Guanine nucleotide-binding protein beta subunit 1| Length = 340 Score = 63.5 bits (153), Expect = 4e-10 Identities = 45/167 (26%), Positives = 80/167 (47%), Gaps = 4/167 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G TG++SC RF +N IV+ S D + +W++ + GH G V ++++SPD Sbjct: 141 GHTGYLSCCRFLDDN---QIVTSSGDMTCALWDIETGQQCTAFTGHTGDVMSLSLSPDFR 197 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQD-SIKIWDLES 364 SG D LWD+ +G + S IN++ F P+ + D + +++D+ + Sbjct: 198 TFISGACDASAKLWDIRDGMCKQTFPGHESDINAVAFFPSGNAFATGSDDATCRLFDIRA 257 Query: 365 KHIVQDLRPEVPVSSKQMLYC--TCLSWSADGSTLYAGYTDGTIRIY 499 E+ + S + C T +++S G L+AGY D ++ Sbjct: 258 DQ-------ELAMYSHDNIICGITSVAFSKSGRLLFAGYDDFNCNVW 297 Score = 56.6 bits (135), Expect = 5e-08 Identities = 47/168 (27%), Positives = 76/168 (45%), Gaps = 5/168 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G TG V + SP+ T +SG+ D S K+W++ + + T GH ++AVA P G+ Sbjct: 182 GHTGDVMSLSLSPD--FRTFISGACDASAKLWDIRDGMCKQTFPGHESDINAVAFFPSGN 239 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSI---INSLCFSPNRYWLCAATQD-SIKIWDL 358 A+G D L+D+ + L +I I S+ FS + L A D + +WD Sbjct: 240 AFATGSDDATCRLFDIRADQELAMYSHDNIICGITSVAFSKSGRLLFAGYDDFNCNVWD- 298 Query: 359 ESKHIVQDLRPE-VPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 +R E V + +CL + DG + G D ++I+ Sbjct: 299 -------SMRQERAGVLAGHDNRVSCLGVTEDGMAVCTGSWDSFLKIW 339 Score = 44.7 bits (104), Expect = 2e-04 Identities = 40/170 (23%), Positives = 71/170 (41%), Gaps = 7/170 (4%) Frame = +2 Query: 17 TGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLT----NCKLRCTLDGHGGYVSAVAVSPD 184 + WV ++P+ + G D +++L N ++ L GH GY+S D Sbjct: 97 SSWVMTCAYAPSG--SFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDD 154 Query: 185 GSLCASGGKDGVTLLWDLTEGKR--LYSLDAGSIINSLCFSPN-RYWLCAATQDSIKIWD 355 + S G D LWD+ G++ ++ G ++ SL SP+ R ++ A S K+WD Sbjct: 155 NQIVTSSG-DMTCALWDIETGQQCTAFTGHTGDVM-SLSLSPDFRTFISGACDASAKLWD 212 Query: 356 LESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 + Q P + +++ G+ G D T R++ I Sbjct: 213 IRDGMCKQTF----PGHESDI---NAVAFFPSGNAFATGSDDATCRLFDI 255 Score = 29.6 bits (65), Expect = 6.1 Identities = 15/56 (26%), Positives = 25/56 (44%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWD 235 + +G D + VW+ + L GH VS + V+ DG +G D +W+ Sbjct: 285 LFAGYDDFNCNVWDSMRQERAGVLAGHDNRVSCLGVTEDGMAVCTGSWDSFLKIWN 340 Score = 29.6 bits (65), Expect = 6.1 Identities = 27/146 (18%), Positives = 59/146 (40%), Gaps = 17/146 (11%) Frame = +2 Query: 122 KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLD-AGSIINSLCF 298 + R TL GH + A+ + D S +DG ++WD +++++ S + + + Sbjct: 46 RTRRTLRGHLAKIYAMHWASDSRNLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAY 105 Query: 299 SPNRYWLCAATQDSI-KIWDLESKHIVQDLRPEVPVSSKQMLYC---------------T 430 +P+ ++ D+I I+ L+++ + E+P + + C T Sbjct: 106 APSGSFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIVTSSGDMT 165 Query: 431 CLSWSADGSTLYAGYTDGTIRIYKIS 508 C W + +T T + +S Sbjct: 166 CALWDIETGQQCTAFTGHTGDVMSLS 191
>GBB1_CAEBR (Q61ZF6) Guanine nucleotide-binding protein beta subunit 1| Length = 340 Score = 63.5 bits (153), Expect = 4e-10 Identities = 45/167 (26%), Positives = 80/167 (47%), Gaps = 4/167 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G TG++SC RF +N IV+ S D + +W++ + GH G V ++++SPD Sbjct: 141 GHTGYLSCCRFLDDN---QIVTSSGDMTCALWDIETGQQCTAFTGHTGDVMSLSLSPDFR 197 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQD-SIKIWDLES 364 SG D LWD+ +G + S IN++ F P+ + D + +++D+ + Sbjct: 198 TFISGACDASAKLWDIRDGMCKQTFPGHESDINAVAFFPSGNAFATGSDDATCRLFDIRA 257 Query: 365 KHIVQDLRPEVPVSSKQMLYC--TCLSWSADGSTLYAGYTDGTIRIY 499 E+ + S + C T +++S G L+AGY D ++ Sbjct: 258 DQ-------ELAMYSHDNIICGITSVAFSKSGRLLFAGYDDFNCNVW 297 Score = 56.6 bits (135), Expect = 5e-08 Identities = 47/168 (27%), Positives = 76/168 (45%), Gaps = 5/168 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G TG V + SP+ T +SG+ D S K+W++ + + T GH ++AVA P G+ Sbjct: 182 GHTGDVMSLSLSPD--FRTFISGACDASAKLWDIRDGMCKQTFPGHESDINAVAFFPSGN 239 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSI---INSLCFSPNRYWLCAATQD-SIKIWDL 358 A+G D L+D+ + L +I I S+ FS + L A D + +WD Sbjct: 240 AFATGSDDATCRLFDIRADQELAMYSHDNIICGITSVAFSKSGRLLFAGYDDFNCNVWD- 298 Query: 359 ESKHIVQDLRPE-VPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 +R E V + +CL + DG + G D ++I+ Sbjct: 299 -------SMRQERAGVLAGHDNRVSCLGVTEDGMAVCTGSWDSFLKIW 339 Score = 44.7 bits (104), Expect = 2e-04 Identities = 40/170 (23%), Positives = 71/170 (41%), Gaps = 7/170 (4%) Frame = +2 Query: 17 TGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLT----NCKLRCTLDGHGGYVSAVAVSPD 184 + WV ++P+ + G D +++L N ++ L GH GY+S D Sbjct: 97 SSWVMTCAYAPSG--SFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDD 154 Query: 185 GSLCASGGKDGVTLLWDLTEGKR--LYSLDAGSIINSLCFSPN-RYWLCAATQDSIKIWD 355 + S G D LWD+ G++ ++ G ++ SL SP+ R ++ A S K+WD Sbjct: 155 NQIVTSSG-DMTCALWDIETGQQCTAFTGHTGDVM-SLSLSPDFRTFISGACDASAKLWD 212 Query: 356 LESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 + Q P + +++ G+ G D T R++ I Sbjct: 213 IRDGMCKQTF----PGHESDI---NAVAFFPSGNAFATGSDDATCRLFDI 255 Score = 29.6 bits (65), Expect = 6.1 Identities = 15/56 (26%), Positives = 25/56 (44%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWD 235 + +G D + VW+ + L GH VS + V+ DG +G D +W+ Sbjct: 285 LFAGYDDFNCNVWDSMRQERAGVLAGHDNRVSCLGVTEDGMAVCTGSWDSFLKIWN 340 Score = 29.6 bits (65), Expect = 6.1 Identities = 27/146 (18%), Positives = 59/146 (40%), Gaps = 17/146 (11%) Frame = +2 Query: 122 KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLD-AGSIINSLCF 298 + R TL GH + A+ + D S +DG ++WD +++++ S + + + Sbjct: 46 RTRRTLRGHLAKIYAMHWASDSRNLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAY 105 Query: 299 SPNRYWLCAATQDSI-KIWDLESKHIVQDLRPEVPVSSKQMLYC---------------T 430 +P+ ++ D+I I+ L+++ + E+P + + C T Sbjct: 106 APSGSFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIVTSSGDMT 165 Query: 431 CLSWSADGSTLYAGYTDGTIRIYKIS 508 C W + +T T + +S Sbjct: 166 CALWDIETGQQCTAFTGHTGDVMSLS 191
>POF1_SCHPO (P87053) F-box/WD-repeat protein pof1 (Skp1-binding protein 1)| Length = 605 Score = 63.5 bits (153), Expect = 4e-10 Identities = 49/165 (29%), Positives = 77/165 (46%), Gaps = 1/165 (0%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G T V C+ F + +VSGS D +VK+W+ + K R TL GH G V++V + D Sbjct: 351 GHTDSVLCLTFD----STLLVSGSADCTVKLWHFSGGK-RITLRGHTGPVNSVRIIRDRG 405 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAG-SIINSLCFSPNRYWLCAATQDSIKIWDLESK 367 L SG D +W L L++ A + SL + +R + C + +IK WD+E K Sbjct: 406 LVLSGSDDSTIKIWSLETNTCLHTFSAHIGPVQSLALADSRLFSC-SLDGTIKQWDIEKK 464 Query: 368 HIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYK 502 V L + +AD L +G DG +++++ Sbjct: 465 KCVHTLFGHIE---------GVWEIAADHLRLISGAHDGVVKVWE 500 Score = 60.1 bits (144), Expect = 4e-09 Identities = 42/151 (27%), Positives = 71/151 (47%), Gaps = 2/151 (1%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G + V+C++F ++SGS D+++++WN + L GH S + ++ D + Sbjct: 311 GHSSGVTCLQFDQCK----LISGSMDKTIRIWNYRTSECISILHGHTD--SVLCLTFDST 364 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDS-IKIWDLESK 367 L SG D LW + GKR+ +NS+ +R + + + DS IKIW LE+ Sbjct: 365 LLVSGSADCTVKLWHFSGGKRITLRGHTGPVNSVRIIRDRGLVLSGSDDSTIKIWSLETN 424 Query: 368 HIVQDLRPEV-PVSSKQMLYCTCLSWSADGS 457 + + PV S + S S DG+ Sbjct: 425 TCLHTFSAHIGPVQSLALADSRLFSCSLDGT 455 Score = 31.6 bits (70), Expect = 1.6 Identities = 20/55 (36%), Positives = 28/55 (50%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLW 232 ++SG+ D VKVW C+ TL H V++VA+ SG +DG LW Sbjct: 487 LISGAHDGVVKVWEA--CECVHTLKNHSEPVTSVALG--DCEVVSGSEDGKIYLW 537 Score = 30.0 bits (66), Expect = 4.6 Identities = 20/59 (33%), Positives = 28/59 (47%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTE 244 + S S D ++K W++ K TL GH V +A D SG DGV +W+ E Sbjct: 447 LFSCSLDGTIKQWDIEKKKCVHTLFGHIEGVWEIAA--DHLRLISGAHDGVVKVWEACE 503
>PRL2_ARATH (Q39190) PP1/PP2A phosphatases pleiotropic regulator PRL2| Length = 479 Score = 63.2 bits (152), Expect = 5e-10 Identities = 40/123 (32%), Positives = 62/123 (50%), Gaps = 3/123 (2%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG 187 +G GWV V F P+N +GS DR++K+W++ L+ TL GH G V +AVS Sbjct: 167 QGHLGWVRSVAFDPSN--EWFCTGSADRTIKIWDVATGVLKLTLTGHIGQVRGLAVSNRH 224 Query: 188 SLCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFS--PNRYWLCAATQDSI-KIWDL 358 + S G D WDL + K + S G + C + P + +DS+ ++WD+ Sbjct: 225 TYMFSAGDDKQVKCWDLEQNKVIRSYH-GHLHGVYCLALHPTLDVVLTGGRDSVCRVWDI 283 Query: 359 ESK 367 +K Sbjct: 284 RTK 286 Score = 44.7 bits (104), Expect = 2e-04 Identities = 30/125 (24%), Positives = 49/125 (39%), Gaps = 2/125 (1%) Frame = +2 Query: 137 LDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLDA--GSIINSLCFSPNR 310 L GH G+V +VA P +G D +WD+ G +L G + + + Sbjct: 166 LQGHLGWVRSVAFDPSNEWFCTGSADRTIKIWDVATGVLKLTLTGHIGQVRGLAVSNRHT 225 Query: 311 YWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTI 490 Y A +K WDLE +++ + +YC L + D + G D Sbjct: 226 YMFSAGDDKQVKCWDLEQNKVIRSYHGHL-----HGVYCLALHPTLD--VVLTGGRDSVC 278 Query: 491 RIYKI 505 R++ I Sbjct: 279 RVWDI 283
>GBB_DICDI (P36408) Guanine nucleotide-binding protein beta subunit| Length = 347 Score = 62.8 bits (151), Expect = 6e-10 Identities = 46/164 (28%), Positives = 78/164 (47%), Gaps = 3/164 (1%) Frame = +2 Query: 17 TGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLC 196 TG++SC RF + IV+ S D + +W++ N H G V +V+VSPD + Sbjct: 150 TGYLSCCRFLNDR---QIVTSSGDMTCILWDVENGTKITEFSDHNGDVMSVSVSPDKNYF 206 Query: 197 ASGGKDGVTLLWDLTEGKRLYSLDAGSI-INSLCFSPNRYWLCAATQD-SIKIWDLES-K 367 SG D LWDL GK + + IN++ + PN + D S +++D+ + + Sbjct: 207 ISGACDATAKLWDLRSGKCVQTFTGHEADINAVQYFPNGLSFGTGSDDASCRLFDIRADR 266 Query: 368 HIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 ++Q + + T + +S G L+AGY D T ++ Sbjct: 267 ELMQYTHDNI------LCGITSVGFSFSGRFLFAGYDDFTCNVW 304 Score = 35.0 bits (79), Expect = 0.14 Identities = 38/157 (24%), Positives = 60/157 (38%), Gaps = 46/157 (29%) Frame = +2 Query: 20 GWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCA 199 G V V SP+ +SG+ D + K+W+L + K T GH ++AV P+G Sbjct: 192 GDVMSVSVSPDK--NYFISGACDATAKLWDLRSGKCVQTFTGHEADINAVQYFPNGLSFG 249 Query: 200 SGGKD------------------------GVTLL--------------------WDLTEG 247 +G D G+T + WD +G Sbjct: 250 TGSDDASCRLFDIRADRELMQYTHDNILCGITSVGFSFSGRFLFAGYDDFTCNVWDTLKG 309 Query: 248 KRLYSLDA-GSIINSLCFSPNRYWLCAATQDS-IKIW 352 +R+ SL G+ ++ L + LC + DS +KIW Sbjct: 310 ERVLSLTGHGNRVSCLGVPTDGMALCTGSWDSLLKIW 346 Score = 33.5 bits (75), Expect = 0.42 Identities = 31/149 (20%), Positives = 62/149 (41%), Gaps = 20/149 (13%) Frame = +2 Query: 122 KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLD-AGSIINSLCF 298 K+R L GH + A+ + D S +DG L+WD +++++ S + + + Sbjct: 53 KVRRNLKGHLAKIYAMHWAEDNVHLVSASQDGKLLVWDGLTTNKVHAIPLRSSWVMTCAY 112 Query: 299 SPNRYWLCAATQDSI-KIWDLESK----HIVQDLRP--------------EVPVSSKQML 421 SP ++ D+I I++L S+ + ++L ++ SS M Sbjct: 113 SPTANFVACGGLDNICSIYNLRSREQPIRVCRELNSHTGYLSCCRFLNDRQIVTSSGDM- 171 Query: 422 YCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 TC+ W + T ++D + +S Sbjct: 172 --TCILWDVENGTKITEFSDHNGDVMSVS 198
>UTP15_MOUSE (Q8C7V3) U3 small nucleolar RNA-associated protein 15 homolog| (Src-associated protein SAW) Length = 528 Score = 62.4 bits (150), Expect = 8e-10 Identities = 51/189 (26%), Positives = 87/189 (46%), Gaps = 10/189 (5%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVS---AVAVSP 181 G T V V F+ +N+ +VSG+ D +VK+W++ N K T H YV A ++P Sbjct: 120 GHTKAVHTVDFTADNYH--VVSGADDYTVKLWDIPNSKEILTFKEHSDYVRCGCASKLNP 177 Query: 182 DGSLCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWD-L 358 D L +G D ++D K + ++ G + S+ P+ L +A +K+WD L Sbjct: 178 D--LFVTGSYDHTVKIFDARTNKNVLCVEHGQPVESVLLFPSGGLLVSAGGRYVKVWDML 235 Query: 359 ESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYK------ISGFSY 520 + ++ L+ TCL S+ G L +G D +++Y + F Y Sbjct: 236 KGGQLLVSLKNHHKT-------VTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSFDY 288 Query: 521 SS*IMYLVL 547 ++ I+ L L Sbjct: 289 AASILSLAL 297 Score = 34.7 bits (78), Expect = 0.19 Identities = 23/108 (21%), Positives = 49/108 (45%), Gaps = 2/108 (1%) Frame = +2 Query: 182 DGSLCASGGKDGVTLLWDLTEGKRLYSLDAGS-IINSLCFSPNRYWLCAATQD-SIKIWD 355 DG L +G +DGV L+D+ L + + ++++ F+ + Y + + D ++K+WD Sbjct: 91 DGQLLVAGSEDGVVQLFDINGRAPLRQFEGHTKAVHTVDFTADNYHVVSGADDYTVKLWD 150 Query: 356 LESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 + + + + + C C S + G D T++I+ Sbjct: 151 IPNSKEILTFK-----EHSDYVRCGCAS-KLNPDLFVTGSYDHTVKIF 192
>PRL1_ARATH (Q42384) PP1/PP2A phosphatases pleiotropic regulator PRL1| Length = 486 Score = 62.4 bits (150), Expect = 8e-10 Identities = 40/122 (32%), Positives = 60/122 (49%), Gaps = 2/122 (1%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG 187 +G GWV V F P+N +GS DR++K+W++ L+ TL GH V +AVS Sbjct: 173 QGHLGWVRSVAFDPSN--EWFCTGSADRTIKIWDVATGVLKLTLTGHIEQVRGLAVSNRH 230 Query: 188 SLCASGGKDGVTLLWDLTEGKRLYSLDAG-SIINSLCFSPNRYWLCAATQDSI-KIWDLE 361 + S G D WDL + K + S S + L P L +DS+ ++WD+ Sbjct: 231 TYMFSAGDDKQVKCWDLEQNKVIRSYHGHLSGVYCLALHPTLDVLLTGGRDSVCRVWDIR 290 Query: 362 SK 367 +K Sbjct: 291 TK 292 Score = 53.9 bits (128), Expect = 3e-07 Identities = 42/152 (27%), Positives = 70/152 (46%), Gaps = 5/152 (3%) Frame = +2 Query: 62 PTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLT 241 P +V+GS D ++K W+L K TL H V A+ + P + AS D T + L Sbjct: 315 PQVVTGSHDTTIKFWDLRYGKTMSTLTHHKKSVRAMTLHPKENAFASASADN-TKKFSLP 373 Query: 242 EGKRLYSL--DAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEV---PVS 406 +G+ +++ +IIN++ + + + SI WD +S H Q V + Sbjct: 374 KGEFCHNMLSQQKTIINAMAVNEDGVMVTGGDNGSIWFWDWKSGHSFQQSETIVQPGSLE 433 Query: 407 SKQMLYCTCLSWSADGSTLYAGYTDGTIRIYK 502 S+ +Y C + GS L D TI+++K Sbjct: 434 SEAGIYAAC--YDNTGSRLVTCEADKTIKMWK 463 Score = 43.9 bits (102), Expect = 3e-04 Identities = 33/126 (26%), Positives = 53/126 (42%), Gaps = 3/126 (2%) Frame = +2 Query: 137 LDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLDAGSI--INSLCFSPNR 310 + GH G+V +VA P +G D +WD+ G +L G I + L S Sbjct: 172 IQGHLGWVRSVAFDPSNEWFCTGSADRTIKIWDVATGVLKLTL-TGHIEQVRGLAVSNRH 230 Query: 311 YWLCAATQD-SIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGT 487 ++ +A D +K WDLE +++ + +YC L + D L G D Sbjct: 231 TYMFSAGDDKQVKCWDLEQNKVIRSYHGHL-----SGVYCLALHPTLD--VLLTGGRDSV 283 Query: 488 IRIYKI 505 R++ I Sbjct: 284 CRVWDI 289
>TAF5_SCHPO (O13282) Transcription initiation factor TFIID subunit 5| (Transcription initiation factor TFIID 72 kDa subunit) (TAFII-72) Length = 643 Score = 62.0 bits (149), Expect = 1e-09 Identities = 45/162 (27%), Positives = 79/162 (48%), Gaps = 8/162 (4%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 V CV F PN+ +++GS D++ ++W++ +GH V+AVA++PDG AS Sbjct: 466 VDCVTFHPNS--AYVLTGSSDKTCRLWDVHRGHSVRVFNGHTQPVTAVAIAPDGHTMASA 523 Query: 206 GKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQ 379 +G+ LWD+ G+R+ ++ I SL FS L + D +++ WD+ + Sbjct: 524 DSEGLIHLWDIGTGRRIKTMRGHRGNIYSLSFSRESTVLVSGGSDCTVRAWDVFKTNYNN 583 Query: 380 DLRPEV------PVSSKQMLYCTCLSWSADGSTLYAGYTDGT 487 + + P S+K + ++WS + A YT T Sbjct: 584 PVSSSLTGSVVTPFSAKTSTF-NEVNWSTSPDQMVALYTKQT 624 Score = 48.5 bits (114), Expect = 1e-05 Identities = 45/168 (26%), Positives = 75/168 (44%), Gaps = 5/168 (2%) Frame = +2 Query: 17 TGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLC 196 +G V FSP+N ++S S D S ++W++ GH G V VA P G Sbjct: 379 SGPVYGTTFSPDN--KYLLSCSEDASARLWSVDTKTALVAYKGHTGPVWDVAFGPFGHYF 436 Query: 197 ASGGKDGVTLLWDLTEGKRLYSLD--AG--SIINSLCFSPN-RYWLCAATQDSIKIWDLE 361 A+ D LW +Y L AG S ++ + F PN Y L ++ + ++WD+ Sbjct: 437 ATASHDQTAQLWSC---DHIYPLRVFAGHLSDVDCVTFHPNSAYVLTGSSDKTCRLWDVH 493 Query: 362 SKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 H V+ V + T ++ + DG T+ + ++G I ++ I Sbjct: 494 RGHSVR-------VFNGHTQPVTAVAIAPDGHTMASADSEGLIHLWDI 534 Score = 32.7 bits (73), Expect = 0.72 Identities = 35/176 (19%), Positives = 70/176 (39%), Gaps = 16/176 (9%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCT-------------LDGHGGYVSA 166 ++C FSP++ I G + +++W++ K L H G V Sbjct: 327 MNCAEFSPDS--TMIACGFQESYIRLWSIKADKKSLPKSTSVEDSDGSVRLLSHSGPVYG 384 Query: 167 VAVSPDGSLCASGGKDGVTLLWDLTEGKRL--YSLDAGSIINSLCFSPNRYWLCAATQD- 337 SPD S +D LW + L Y G + + + F P ++ A+ D Sbjct: 385 TTFSPDNKYLLSCSEDASARLWSVDTKTALVAYKGHTGPVWD-VAFGPFGHYFATASHDQ 443 Query: 338 SIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 + ++W + HI + V + + C+++ + + + G +D T R++ + Sbjct: 444 TAQLWSCD--HIY-----PLRVFAGHLSDVDCVTFHPNSAYVLTGSSDKTCRLWDV 492
>WDR47_MOUSE (Q8CGF6) WD-repeat protein 47| Length = 920 Score = 61.6 bits (148), Expect = 1e-09 Identities = 46/159 (28%), Positives = 79/159 (49%), Gaps = 11/159 (6%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLT--NCK--LRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWD 235 I SGS D++V+ W+L +C + T G G V++VAV P G L A+G +D +L+D Sbjct: 770 IASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYD 829 Query: 236 LTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQDLRPEVPV-- 403 + G+ + S S + S+ FSP ++L + D IK+ DL+ DL ++P+ Sbjct: 830 IRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQG-----DLTKQLPLMV 884 Query: 404 ---SSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISG 511 +++ C W + + D T+ ++ SG Sbjct: 885 VGEHKDKVIQC---RWHTQDLSFLSSSADRTVTLWTYSG 920 Score = 32.3 bits (72), Expect = 0.94 Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 6/91 (6%) Frame = +2 Query: 137 LDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSL-----DAGSIINSLCFS 301 L GH G++ A+ + G + ASG +D WDL + + GS + S+ Sbjct: 752 LSGHTGHILAL-YTWSGWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVD 810 Query: 302 PNRYWLCAATQD-SIKIWDLESKHIVQDLRP 391 P+ L +D S ++D+ +VQ P Sbjct: 811 PSGRLLATGQEDSSCMLYDIRGGRMVQSYHP 841
>KMHB_DICDI (P90648) Myosin heavy chain kinase B (EC 2.7.11.7) (MHCK B)| Length = 732 Score = 61.6 bits (148), Expect = 1e-09 Identities = 47/156 (30%), Positives = 76/156 (48%), Gaps = 3/156 (1%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRC--TLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLT 241 + SGS D S+KVW+L KLRC TL+GH V V + + SG D +WDL Sbjct: 515 LFSGSSDHSIKVWDLK--KLRCIFTLEGHDKPVHTVLL--NDKYLFSGSSDKTIKVWDLK 570 Query: 242 EGKRLYSLDA-GSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQM 418 + Y+L++ + +LC S +Y + +IK+WDL++ L+ + Sbjct: 571 TLECKYTLESHARAVKTLCIS-GQYLFSGSNDKTIKVWDLKTFRCNYTLK-----GHTKW 624 Query: 419 LYCTCLSWSADGSTLYAGYTDGTIRIYKISGFSYSS 526 + C+ G+ LY+G D TIR++ + S+ Sbjct: 625 VTTICIL----GTNLYSGSYDKTIRVWNLKSLECSA 656 Score = 48.1 bits (113), Expect = 2e-05 Identities = 39/148 (26%), Positives = 68/148 (45%), Gaps = 2/148 (1%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 + SGS D+++KVW+L + + TL+ H V + +S G SG D +WDL Sbjct: 555 LFSGSSDKTIKVWDLKTLECKYTLESHARAVKTLCIS--GQYLFSGSNDKTIKVWDLKTF 612 Query: 248 KRLYSLDAGS-IINSLC-FSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQML 421 + Y+L + + ++C N Y + +I++W+L+S LR + M+ Sbjct: 613 RCNYTLKGHTKWVTTICILGTNLY--SGSYDKTIRVWNLKSLECSATLRGH-DRWVEHMV 669 Query: 422 YCTCLSWSADGSTLYAGYTDGTIRIYKI 505 C L L+ D TI+I+ + Sbjct: 670 ICDKL--------LFTASDDNTIKIWDL 689 Score = 45.4 bits (106), Expect = 1e-04 Identities = 29/117 (24%), Positives = 57/117 (48%), Gaps = 2/117 (1%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG 187 +G T WV+ + N + SGS+D++++VWNL + + TL GH +V + + Sbjct: 619 KGHTKWVTTICILGTN----LYSGSYDKTIRVWNLKSLECSATLRGHDRWVEHMVIC--D 672 Query: 188 SLCASGGKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQD-SIKIW 352 L + D +WDL + +L+ + + L ++ + + + D SI++W Sbjct: 673 KLLFTASDDNTIKIWDLETLRCNTTLEGHNATVQCLAVWEDKKCVISCSHDQSIRVW 729 Score = 44.3 bits (103), Expect = 2e-04 Identities = 28/99 (28%), Positives = 49/99 (49%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 + SGS D+++KVW+L + TL GH +V+ + + G+ SG D +W+L Sbjct: 595 LFSGSNDKTIKVWDLKTFRCNYTLKGHTKWVTTICIL--GTNLYSGSYDKTIRVWNLKSL 652 Query: 248 KRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLES 364 + +L ++ A+ ++IKIWDLE+ Sbjct: 653 ECSATLRGHDRWVEHMVICDKLLFTASDDNTIKIWDLET 691
>GBB_LOLFO (P23232) Guanine nucleotide-binding protein beta subunit| Length = 341 Score = 61.6 bits (148), Expect = 1e-09 Identities = 44/170 (25%), Positives = 83/170 (48%), Gaps = 5/170 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G TG++SC RF +N IV+ S D + +WN+ + GH G V +++++PD Sbjct: 142 GHTGYLSCCRFIDDN---QIVTSSGDMTCALWNIETGNQITSFGGHTGDVMSLSLAPDMR 198 Query: 191 LCASGGKDGVTLLWDLTEG--KRLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLE 361 SG D L+D+ +G K+ ++ S IN++ + PN + + D + +++D+ Sbjct: 199 TFVSGACDASAKLFDIRDGICKQTFT-GHESDINAITYFPNGFAFATGSDDATCRLFDIR 257 Query: 362 SKHIVQDLRPEVPVSSKQMLYC--TCLSWSADGSTLYAGYTDGTIRIYKI 505 + E+ + S + C T +++S G L GY D ++ + Sbjct: 258 ADQ-------EIGMYSHDNIICGITSVAFSKSGRLLLGGYDDFNCNVWDV 300 Score = 48.1 bits (113), Expect = 2e-05 Identities = 41/167 (24%), Positives = 75/167 (44%), Gaps = 4/167 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G TG V + +P+ T VSG+ D S K++++ + + T GH ++A+ P+G Sbjct: 183 GHTGDVMSLSLAPD--MRTFVSGACDASAKLFDIRDGICKQTFTGHESDINAITYFPNGF 240 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSI---INSLCFSPNRYWLCAATQD-SIKIWDL 358 A+G D L+D+ + + +I I S+ FS + L D + +WD Sbjct: 241 AFATGSDDATCRLFDIRADQEIGMYSHDNIICGITSVAFSKSGRLLLGGYDDFNCNVWD- 299 Query: 359 ESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 +++ R V + +CL + DG + G D ++I+ Sbjct: 300 ----VLKQERAGVLAGHDNRV--SCLGVTEDGMAVATGSWDSFLKIW 340 Score = 37.4 bits (85), Expect = 0.029 Identities = 29/120 (24%), Positives = 54/120 (45%), Gaps = 6/120 (5%) Frame = +2 Query: 17 TGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLT----NCKLRCTLDGHGGYVSAVAVSPD 184 + WV ++P+ + G D +++L N ++ L GH GY+S D Sbjct: 98 SSWVMTCAYAPSG--NYVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFIDD 155 Query: 185 GSLCASGGKDGVTLLWDLTEGKRLYSLDAGS-IINSLCFSPN-RYWLCAATQDSIKIWDL 358 + S G D LW++ G ++ S + + SL +P+ R ++ A S K++D+ Sbjct: 156 NQIVTSSG-DMTCALWNIETGNQITSFGGHTGDVMSLSLAPDMRTFVSGACDASAKLFDI 214 Score = 32.7 bits (73), Expect = 0.72 Identities = 16/56 (28%), Positives = 27/56 (48%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWD 235 ++ G D + VW++ + L GH VS + V+ DG A+G D +W+ Sbjct: 286 LLGGYDDFNCNVWDVLKQERAGVLAGHDNRVSCLGVTEDGMAVATGSWDSFLKIWN 341 Score = 30.0 bits (66), Expect = 4.6 Identities = 27/139 (19%), Positives = 57/139 (41%), Gaps = 20/139 (14%) Frame = +2 Query: 122 KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLD-AGSIINSLCF 298 + R TL GH + A+ + D S +DG ++WD +++++ S + + + Sbjct: 47 RTRRTLRGHLAKIYAMHWASDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAY 106 Query: 299 SPN-RYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYC---------------T 430 +P+ Y C + I+ L+++ + E+P + + C T Sbjct: 107 APSGNYVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFIDDNQIVTSSGDMT 166 Query: 431 CLSWSADGS---TLYAGYT 478 C W+ + T + G+T Sbjct: 167 CALWNIETGNQITSFGGHT 185
>COPB2_YEAST (P41811) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| Length = 889 Score = 61.6 bits (148), Expect = 1e-09 Identities = 48/158 (30%), Positives = 76/158 (48%), Gaps = 7/158 (4%) Frame = +2 Query: 62 PTIVSGSWDRSVKVWNL-TNCKLRCTLDGHGGYVSAVAVSP-DGSLCASGGKDGVTLLWD 235 P ++SGS D +VK+WN N L T +GH +V VA +P D S ASG D +W Sbjct: 110 PYVLSGSDDLTVKLWNWENNWALEQTFEGHEHFVMCVAFNPKDPSTFASGCLDRTVKVWS 169 Query: 236 LTEGKRLYSLDAGSI--INSLCFSP---NRYWLCAATQDSIKIWDLESKHIVQDLRPEVP 400 L + ++L G +N + + P Y + A+ +IKIWD ++K V L + Sbjct: 170 LGQSTPNFTLTTGQERGVNYVDYYPLPDKPYMITASDDLTIKIWDYQTKSCVATLEGHMS 229 Query: 401 VSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISGF 514 S + + T + +G DGT++I+ S + Sbjct: 230 NVSFAVFHPTL-------PIIISGSEDGTLKIWNSSTY 260 Score = 41.6 bits (96), Expect = 0.002 Identities = 23/83 (27%), Positives = 40/83 (48%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 V+ V + P P +++ S D ++K+W+ TL+GH VS P + SG Sbjct: 187 VNYVDYYPLPDKPYMITASDDLTIKIWDYQTKSCVATLEGHMSNVSFAVFHPTLPIIISG 246 Query: 206 GKDGVTLLWDLTEGKRLYSLDAG 274 +DG +W+ + K +L+ G Sbjct: 247 SEDGTLKIWNSSTYKVEKTLNVG 269
>TBL3_HUMAN (Q12788) WD-repeat protein SAZD (Transducin beta-like 3 protein)| Length = 519 Score = 61.6 bits (148), Expect = 1e-09 Identities = 37/153 (24%), Positives = 69/153 (45%), Gaps = 12/153 (7%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG 187 RG G V V F P+ + S + D +++VW+L + L H V+++A S DG Sbjct: 34 RGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWSLQDRSCLAVLTAHYSAVTSLAFSADG 93 Query: 188 SLCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCF------------SPNRYWLCAAT 331 S G+D + ++WDL + ++ + + SP Y+L A Sbjct: 94 HTMLSSGRDKICIIWDLQSCQATRTVPVFESVEAAVLLPEEPVSQLGVKSPGLYFLTAGD 153 Query: 332 QDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCT 430 Q ++++W+ S V + + P +++ +CT Sbjct: 154 QGTLRVWEAASGQCVY-TQAQPPGPGQELTHCT 185 Score = 39.3 bits (90), Expect = 0.008 Identities = 43/185 (23%), Positives = 76/185 (41%), Gaps = 23/185 (12%) Frame = +2 Query: 20 GWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKL---------------RCTLDGHGG 154 G V C R + +V+GS D +VK+W L L T H Sbjct: 311 GTVCCSRLKES----FLVTGSQDCTVKLWPLPKALLSKNTAPDNGPILLQAHTTQRCHDK 366 Query: 155 YVSAVAVSPDGSLCASGGKDGVTLLWDLTE--------GKRLYSLDAGSIINSLCFSPNR 310 +++VA++P+ L A+G +D LW L + G R+ S + S+ + C+ R Sbjct: 367 DINSVAIAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRVASGASSSLPWTRCWP--R 424 Query: 311 YWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTI 490 L A + S+H+ ML C +++ + G+ L + +DG + Sbjct: 425 PQLMAPSSSGHSRTSAVSRHL-----------RGTMLLCLKVAFVSRGTQLLSSGSDGLV 473 Query: 491 RIYKI 505 +++ I Sbjct: 474 KLWTI 478 Score = 39.3 bits (90), Expect = 0.008 Identities = 28/109 (25%), Positives = 51/109 (46%), Gaps = 4/109 (3%) Frame = +2 Query: 167 VAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSL-DAGSIINSLCFSPNRYWL---CAATQ 334 +A P +L A+GG DG +WD+ + + +++ + F P+ L +AT Sbjct: 1 MAFDPTSTLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLLLFSSATD 60 Query: 335 DSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTD 481 +I++W L+ R + V + T L++SADG T+ + D Sbjct: 61 AAIRVWSLQD-------RSCLAVLTAHYSAVTSLAFSADGHTMLSSGRD 102
>WDR47_HUMAN (O94967) WD-repeat protein 47| Length = 919 Score = 61.2 bits (147), Expect = 2e-09 Identities = 45/159 (28%), Positives = 79/159 (49%), Gaps = 11/159 (6%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLT--NCK--LRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWD 235 I SGS D++V+ W+L +C + T G G V++VAV P G L A+G +D +L+D Sbjct: 769 IASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYD 828 Query: 236 LTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQDLRPEVPV-- 403 + G+ + S S + S+ FSP ++L + D IK+ DL+ DL ++P+ Sbjct: 829 IRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQG-----DLTKQLPIMV 883 Query: 404 ---SSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISG 511 +++ C W + + D T+ ++ +G Sbjct: 884 VGEHKDKVIQC---RWHTQDLSFLSSSADRTVTLWTYNG 919 Score = 32.3 bits (72), Expect = 0.94 Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 6/91 (6%) Frame = +2 Query: 137 LDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSL-----DAGSIINSLCFS 301 L GH G++ A+ + G + ASG +D WDL + + GS + S+ Sbjct: 751 LSGHTGHILAL-YTWSGWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVD 809 Query: 302 PNRYWLCAATQD-SIKIWDLESKHIVQDLRP 391 P+ L +D S ++D+ +VQ P Sbjct: 810 PSGRLLATGQEDSSCMLYDIRGGRMVQSYHP 840
>TAF5_DROME (P49846) Transcription initiation factor TFIID subunit 5| (Transcription initiation factor TFIID 85 kDa subunit) (p85) (TAFII-80) Length = 704 Score = 60.8 bits (146), Expect = 2e-09 Identities = 41/113 (36%), Positives = 65/113 (57%), Gaps = 3/113 (2%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVW-NLTNCKLRCTLDGHGGYVSAVAVSPDGSLCAS 202 V CV+F PN+ + +GS DR+V++W N+T +R + GH G VS++A S G AS Sbjct: 537 VDCVQFHPNS--NYVATGSSDRTVRLWDNMTGQSVR-LMTGHKGSVSSLAFSACGRYLAS 593 Query: 203 GGKDGVTLLWDLTEGKRLYS-LDAGSIINSLCFSPNRYWLCAATQD-SIKIWD 355 G D ++WDL+ G + + L S + ++ FS + L AA D ++ +WD Sbjct: 594 GSVDHNIIIWDLSNGSLVTTLLRHTSTVTTITFSRDGTVLAAAGLDNNLTLWD 646 Score = 57.8 bits (138), Expect = 2e-08 Identities = 45/158 (28%), Positives = 74/158 (46%), Gaps = 3/158 (1%) Frame = +2 Query: 35 VRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKD 214 VRF+P+ + VS S+D++ ++W + + GH V V P+ + A+G D Sbjct: 498 VRFAPHGYY--FVSCSYDKTARLWATDSNQALRVFVGHLSDVDCVQFHPNSNYVATGSSD 555 Query: 215 GVTLLWDLTEGK--RLYSLDAGSIINSLCFSP-NRYWLCAATQDSIKIWDLESKHIVQDL 385 LWD G+ RL + GS ++SL FS RY + +I IWDL + +V L Sbjct: 556 RTVRLWDNMTGQSVRLMTGHKGS-VSSLAFSACGRYLASGSVDHNIIIWDLSNGSLVTTL 614 Query: 386 RPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 + T +++S DG+ L A D + ++ Sbjct: 615 -------LRHTSTVTTITFSRDGTVLAAAGLDNNLTLW 645 Score = 41.6 bits (96), Expect = 0.002 Identities = 44/175 (25%), Positives = 75/175 (42%), Gaps = 3/175 (1%) Frame = +2 Query: 2 SARGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSP 181 S G TG V F+P ++S S D ++++W+L T GH V V +P Sbjct: 445 SLMGHTGPVYRCAFAPE--MNLLLSCSEDSTIRLWSLLTWSCVVTYRGHVYPVWDVRFAP 502 Query: 182 DGSLCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLC--FSPNRYWLCAATQD-SIKIW 352 G S D LW T+ + + G + + C F PN ++ + D ++++W Sbjct: 503 HGYYFVSCSYDKTARLW-ATDSNQALRVFVGHLSDVDCVQFHPNSNYVATGSSDRTVRLW 561 Query: 353 DLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISGFS 517 D + V+ + + + L++SA G L +G D I I+ +S S Sbjct: 562 DNMTGQSVR-------LMTGHKGSVSSLAFSACGRYLASGSVDHNIIIWDLSNGS 609 Score = 37.7 bits (86), Expect = 0.022 Identities = 39/192 (20%), Positives = 76/192 (39%), Gaps = 34/192 (17%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLD--------------------- 142 V+C S ++ + G D SV++W+LT KLR D Sbjct: 380 VTCAEISDDS--TMLACGFGDSSVRIWSLTPAKLRTLKDADSLRELDKESADINVRMLDD 437 Query: 143 ----------GHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLDAGSI--IN 286 GH G V A +P+ +L S +D LW L + + G + + Sbjct: 438 RSGEVTRSLMGHTGPVYRCAFAPEMNLLLSCSEDSTIRLWSLLTWSCVVTY-RGHVYPVW 496 Query: 287 SLCFSPNRYWLCAATQD-SIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTL 463 + F+P+ Y+ + + D + ++W +S ++ V + C+ + + + + Sbjct: 497 DVRFAPHGYYFVSCSYDKTARLWATDSNQALR-------VFVGHLSDVDCVQFHPNSNYV 549 Query: 464 YAGYTDGTIRIY 499 G +D T+R++ Sbjct: 550 ATGSSDRTVRLW 561
>GBB_ARATH (P49177) Guanine nucleotide-binding protein beta subunit| (transducin) (AGB1) Length = 377 Score = 60.8 bits (146), Expect = 2e-09 Identities = 51/171 (29%), Positives = 78/171 (45%), Gaps = 9/171 (5%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRC--TLDGHGGYVSAVAVSPDGSLCA 199 VS +PN F +SGS D + ++W+ T R T GH G V+ V PDG Sbjct: 210 VSISGSNPNWF----ISGSCDSTARLWD-TRAASRAVRTFHGHEGDVNTVKFFPDGYRFG 264 Query: 200 SGGKDGVTLLWDLTEGKRL-----YSLDAGSIINSLCFSPNRYWLCA--ATQDSIKIWDL 358 +G DG L+D+ G +L + + S+ FS + L A A+ ++ +WD Sbjct: 265 TGSDDGTCRLYDIRTGHQLQVYQPHGDGENGPVTSIAFSVSGRLLFAGYASNNTCYVWDT 324 Query: 359 ESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISG 511 +V DL + ++ +CL SADGS L G D ++I+ G Sbjct: 325 LLGEVVLDLGLQQDSHRNRI---SCLGLSADGSALCTGSWDSNLKIWAFGG 372 Score = 33.9 bits (76), Expect = 0.32 Identities = 25/93 (26%), Positives = 45/93 (48%), Gaps = 2/93 (2%) Frame = +2 Query: 134 TLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLDAG-SIINSLCFSPNR 310 TL GH G V ++ +P+ + S +DG ++W+ ++ +++ + + + FSPN Sbjct: 60 TLQGHTGKVYSLDWTPERNRIVSASQDGRLIVWNALTSQKTHAIKLPCAWVMTCAFSPNG 119 Query: 311 YWLCAATQDSI-KIWDLESKHIVQDLRPEVPVS 406 + DS+ I+ L S D VPVS Sbjct: 120 QSVACGGLDSVCSIFSLSS---TADKDGTVPVS 149
>SPG16_MOUSE (Q8K450) Sperm-associated antigen 16 protein (PF20 protein homolog)| Length = 639 Score = 60.5 bits (145), Expect = 3e-09 Identities = 51/165 (30%), Positives = 82/165 (49%), Gaps = 2/165 (1%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G T V+ + F P F+ +++ S D+++ VW+ K +L GH V+ +P G Sbjct: 484 GHTDSVNSIEFFP--FSNILLTASADKTLSVWDARTGKCEQSLYGHMHSVNDATFTPRGH 541 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAG-SIINSLCFSPNRYWLCAATQDS-IKIWDLES 364 + AS GVT LWD + + S+D G S N + F + L A+ + I + DL+S Sbjct: 542 IIASCDARGVTKLWDFRKLIPIVSIDVGPSSGNEVNFDQSGRVLAQASANGIIHLLDLKS 601 Query: 365 KHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 I + + E V S + +S G LY+G +DGTIR++ Sbjct: 602 GQIHKLVGHESEVHS--------VVFSHLGENLYSGGSDGTIRLW 638 Score = 52.0 bits (123), Expect = 1e-06 Identities = 34/127 (26%), Positives = 59/127 (46%), Gaps = 2/127 (1%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G T W+S F P+ + + S D ++K+W+L + TL+GH V + G Sbjct: 400 GHTDWLSGCCFHPSG--SKLATSSGDSTIKLWDLNKGECTLTLEGHNHAVWSCTWHSCGD 457 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGS-IINSLCFSP-NRYWLCAATQDSIKIWDLES 364 AS D + +WD+ + Y+L + +NS+ F P + L A+ ++ +WD + Sbjct: 458 FVASASLDMTSKIWDVNSERCRYTLYGHTDSVNSIEFFPFSNILLTASADKTLSVWDART 517 Query: 365 KHIVQDL 385 Q L Sbjct: 518 GKCEQSL 524 Score = 44.3 bits (103), Expect = 2e-04 Identities = 29/111 (26%), Positives = 51/111 (45%), Gaps = 2/111 (1%) Frame = +2 Query: 29 SCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGG 208 SC S +F + S S D + K+W++ + + R TL GH V+++ P ++ + Sbjct: 449 SCTWHSCGDF---VASASLDMTSKIWDVNSERCRYTLYGHTDSVNSIEFFPFSNILLTAS 505 Query: 209 KDGVTLLWDLTEGKRLYSLDAG-SIINSLCFSPNRYWLCAATQDSI-KIWD 355 D +WD GK SL +N F+P + + + + K+WD Sbjct: 506 ADKTLSVWDARTGKCEQSLYGHMHSVNDATFTPRGHIIASCDARGVTKLWD 556 Score = 43.1 bits (100), Expect = 5e-04 Identities = 32/116 (27%), Positives = 52/116 (44%), Gaps = 2/116 (1%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 VSC+ P ++S S DR K+ L + T GH ++S P GS A+ Sbjct: 363 VSCIVMHPCR--DYLISCSEDRLWKMVGLPQGNVLLTGSGHTDWLSGCCFHPSGSKLATS 420 Query: 206 GKDGVTLLWDLTEGKRLYSLDA--GSIINSLCFSPNRYWLCAATQDSIKIWDLESK 367 D LWDL +G+ +L+ ++ + S + A+ + KIWD+ S+ Sbjct: 421 SGDSTIKLWDLNKGECTLTLEGHNHAVWSCTWHSCGDFVASASLDMTSKIWDVNSE 476
>YQF1_SCHPO (O94394) Hypothetical WD-repeat protein C126.01c in chromosome III| Length = 369 Score = 59.3 bits (142), Expect = 7e-09 Identities = 46/174 (26%), Positives = 78/174 (44%), Gaps = 8/174 (4%) Frame = +2 Query: 8 RGPTGWVSCVRFSP---NNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVS 178 +G +G V+C + + I +GSWD ++K WN++ + TL GH YV + + Sbjct: 82 KGHSGPVTCCQIESLRKDGKVRHIYTGSWDHTIKKWNVSTGECVETLIGHTDYVKCLLLL 141 Query: 179 PDGSLCASGGKDGVTLLWDLTE--GKRLYSLDAGSI-INSLCFSPNR--YWLCAATQDSI 343 + L SG D ++WD++ + LY L S I + PN +W C ++ SI Sbjct: 142 EEEGLLLSGSTDASLIVWDVSSQPSRLLYKLTGHSRGIECITRQPNTDIFWTC-GSESSI 200 Query: 344 KIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 + W + +K L E + +YC D L+ D T+R + + Sbjct: 201 RCWHI-TKVGGSQLEEEGFWGHQSNVYCLLFD-PQDSEALWTASADKTVREWSL 252 Score = 38.9 bits (89), Expect = 0.010 Identities = 31/114 (27%), Positives = 55/114 (48%), Gaps = 2/114 (1%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 V C+ F P + + + + S D++V+ W+L T H + V DG++ A+ Sbjct: 225 VYCLLFDPQD-SEALWTASADKTVREWSLYQGIHEETRMEHPDVCTDVLTLADGNI-ATA 282 Query: 206 GKDGVTLLWDLTEG--KRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLE 361 +D +WD T G K +YS S+ L + Y + ++ +I++WDLE Sbjct: 283 CRDEEIRVWDTTTGNVKDIYSGHYESVTKILQWKS--YLISSSLDQTIRVWDLE 334
>GBB1_DROME (P26308) Guanine nucleotide-binding protein beta subunit 1| Length = 340 Score = 59.3 bits (142), Expect = 7e-09 Identities = 46/167 (27%), Positives = 77/167 (46%), Gaps = 4/167 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G G++SC RF +N IV+ S D S +W++ + GH G V A++++P Sbjct: 141 GHGGYLSCCRFLDDN---QIVTSSGDMSCGLWDIETGLQVTSFLGHTGDVMALSLAPQCK 197 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQD-SIKIWDLES 364 SG D LWD+ EG + S IN++ F PN + D + +++D+ + Sbjct: 198 TFVSGACDASAKLWDIREGVCKQTFPGHESDINAVTFFPNGQAFATGSDDATCRLFDIRA 257 Query: 365 KHIVQDLRPEVPVSSKQMLYC--TCLSWSADGSTLYAGYTDGTIRIY 499 E+ + S + C T +++S G L AGY D ++ Sbjct: 258 DQ-------ELAMYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVW 297 Score = 52.8 bits (125), Expect = 7e-07 Identities = 43/167 (25%), Positives = 73/167 (43%), Gaps = 4/167 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G TG V + +P T VSG+ D S K+W++ + T GH ++AV P+G Sbjct: 182 GHTGDVMALSLAPQ--CKTFVSGACDASAKLWDIREGVCKQTFPGHESDINAVTFFPNGQ 239 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSI---INSLCFSPNRYWLCAATQD-SIKIWDL 358 A+G D L+D+ + L +I I S+ FS + L A D + +WD Sbjct: 240 AFATGSDDATCRLFDIRADQELAMYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWD- 298 Query: 359 ESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 ++ R + + +CL + +G + G D +R++ Sbjct: 299 ----TMKAERSGILAGHDNRV--SCLGVTENGMAVATGSWDSFLRVW 339 Score = 44.3 bits (103), Expect = 2e-04 Identities = 40/169 (23%), Positives = 69/169 (40%), Gaps = 6/169 (3%) Frame = +2 Query: 17 TGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLT----NCKLRCTLDGHGGYVSAVAVSPD 184 + WV ++P+ + G D ++NL N ++ L GHGGY+S D Sbjct: 97 SSWVMTCAYAPSG--SYVACGGLDNMCSIYNLKTREGNVRVSRELPGHGGYLSCCRFLDD 154 Query: 185 GSLCASGGKDGVTLLWDLTEGKRLYS-LDAGSIINSLCFSPN-RYWLCAATQDSIKIWDL 358 + S G D LWD+ G ++ S L + +L +P + ++ A S K+WD+ Sbjct: 155 NQIVTSSG-DMSCGLWDIETGLQVTSFLGHTGDVMALSLAPQCKTFVSGACDASAKLWDI 213 Query: 359 ESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 Q P + +++ +G G D T R++ I Sbjct: 214 REGVCKQTF----PGHESDI---NAVTFFPNGQAFATGSDDATCRLFDI 255 Score = 30.8 bits (68), Expect = 2.7 Identities = 15/56 (26%), Positives = 27/56 (48%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWD 235 +++G D + VW+ + L GH VS + V+ +G A+G D +W+ Sbjct: 285 LLAGYDDFNCNVWDTMKAERSGILAGHDNRVSCLGVTENGMAVATGSWDSFLRVWN 340 Score = 30.0 bits (66), Expect = 4.6 Identities = 22/107 (20%), Positives = 47/107 (43%), Gaps = 2/107 (1%) Frame = +2 Query: 122 KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLD-AGSIINSLCF 298 + R TL GH + A+ D S +DG ++WD +++++ S + + + Sbjct: 46 RTRRTLRGHLAKIYAMHWGNDSRNLVSASQDGKLIVWDSHTTNKVHAIPLRSSWVMTCAY 105 Query: 299 SPN-RYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCL 436 +P+ Y C + I++L+++ + E+P + C L Sbjct: 106 APSGSYVACGGLDNMCSIYNLKTREGNVRVSRELPGHGGYLSCCRFL 152
>PRP46_ASHGO (Q75BY3) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 425 Score = 59.3 bits (142), Expect = 7e-09 Identities = 39/127 (30%), Positives = 63/127 (49%), Gaps = 2/127 (1%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G TGWV CV P + A +GS D +++VW+L KL+ TL GH V + +S Sbjct: 111 GHTGWVRCVCVDPVDNA-WFATGSNDSTIRVWDLATGKLKVTLQGHIMTVRDICISARHP 169 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAG-SIINSLCFSPNRYWLCAATQDS-IKIWDLES 364 S +D + WDL + S ++S+ P+ + +A +DS +++WD+ S Sbjct: 170 YMFSASQDKLVKCWDLERNTVVRDFHGTLSGVHSVDLHPSLDLIVSAGRDSVVRVWDIRS 229 Query: 365 KHIVQDL 385 + V L Sbjct: 230 RSCVLTL 236 Score = 55.8 bits (133), Expect = 8e-08 Identities = 31/90 (34%), Positives = 48/90 (53%), Gaps = 3/90 (3%) Frame = +2 Query: 122 KLRCTLDGHGGYVSAVAVSP-DGSLCASGGKDGVTLLWDLTEGKRLYSLDAGSI-INSLC 295 KL ++GH G+V V V P D + A+G D +WDL GK +L + + +C Sbjct: 104 KLTRVINGHTGWVRCVCVDPVDNAWFATGSNDSTIRVWDLATGKLKVTLQGHIMTVRDIC 163 Query: 296 FSPNRYWLCAATQDS-IKIWDLESKHIVQD 382 S ++ +A+QD +K WDLE +V+D Sbjct: 164 ISARHPYMFSASQDKLVKCWDLERNTVVRD 193 Score = 53.9 bits (128), Expect = 3e-07 Identities = 39/145 (26%), Positives = 63/145 (43%), Gaps = 1/145 (0%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 IVS D V+VW++ + TL GH G ++ V P S D LWDL G Sbjct: 213 IVSAGRDSVVRVWDIRSRSCVLTLAGHRGPINKVRCLPVDPQIVSCSTDATVKLWDLVAG 272 Query: 248 KRLYSLDAGS-IINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLY 424 K + +L + L F+P + +A D I+ W L ++ + +S+ + Sbjct: 273 KPMKTLTHHKRNVRDLAFNPTEFSFASACTDDIRSWKLVDGQLLTNF------NSEALGI 326 Query: 425 CTCLSWSADGSTLYAGYTDGTIRIY 499 L+ + DG L+AG G + + Sbjct: 327 VNTLACNQDG-VLFAGGDTGELSFF 350 Score = 47.0 bits (110), Expect = 4e-05 Identities = 45/168 (26%), Positives = 72/168 (42%), Gaps = 3/168 (1%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG 187 RGP V C+ P IVS S D +VK+W+L K TL H V +A +P Sbjct: 240 RGPINKVRCLPVDPQ-----IVSCSTDATVKLWDLVAGKPMKTLTHHKRNVRDLAFNPTE 294 Query: 188 SLCASGGKDGVTLLWDLTEGKRL--YSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLE 361 AS D + W L +G+ L ++ +A I+N+L + + + +D + Sbjct: 295 FSFASACTDDIR-SWKLVDGQLLTNFNSEALGIVNTLACNQDGVLFAGGDTGELSFFDYK 353 Query: 362 SKHIVQDLR-PEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYK 502 + H Q L +P S + ++ G L D +I+I+K Sbjct: 354 TGHKFQKLETTAMPGSLESEKGVLASTFDRTGLRLLTCERDKSIKIWK 401
>GROU_DROME (P16371) Protein groucho (Enhancer of split m9/10 protein)| (E(spl)m9/10) Length = 719 Score = 58.9 bits (141), Expect = 9e-09 Identities = 32/85 (37%), Positives = 43/85 (50%) Frame = +2 Query: 86 DRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSL 265 D ++ VW+L N L GH S + +SPDGS +GG D WDL EG++L Sbjct: 544 DGNIAVWDLHNEILVRQFQGHTDGASCIDISPDGSRLWTGGLDNTVRSWDLREGRQLQQH 603 Query: 266 DAGSIINSLCFSPNRYWLCAATQDS 340 D S I SL + P WL ++S Sbjct: 604 DFSSQIFSLGYCPTGDWLAVGMENS 628 Score = 47.0 bits (110), Expect = 4e-05 Identities = 37/148 (25%), Positives = 64/148 (43%), Gaps = 11/148 (7%) Frame = +2 Query: 95 VKVWNLTN-------CKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL---TE 244 VKVW+++ +L C Y+ +V + PDG GG+ +WDL T Sbjct: 456 VKVWDISQPGNKNPVSQLDCLQ--RDNYIRSVKLLPDGRTLIVGGEASNLSIWDLASPTP 513 Query: 245 GKRLYSLDAGSIINSLCFSPN-RYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQML 421 + A +L SP+ + + +I +WDL ++ +V+ + +S Sbjct: 514 RIKAELTSAAPACYALAISPDSKVCFSCCSDGNIAVWDLHNEILVRQFQGHTDGAS---- 569 Query: 422 YCTCLSWSADGSTLYAGYTDGTIRIYKI 505 C+ S DGS L+ G D T+R + + Sbjct: 570 ---CIDISPDGSRLWTGGLDNTVRSWDL 594 Score = 37.7 bits (86), Expect = 0.022 Identities = 34/136 (25%), Positives = 58/136 (42%), Gaps = 6/136 (4%) Frame = +2 Query: 65 TIVSGSWDRSVKVWNLTNC--KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL 238 T++ G ++ +W+L + +++ L A+A+SPD +C S DG +WDL Sbjct: 493 TLIVGGEASNLSIWDLASPTPRIKAELTSAAPACYALAISPDSKVCFSCCSDGNIAVWDL 552 Query: 239 TEGKRLYSLDAGSIINSLC--FSP--NRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVS 406 + L G + C SP +R W ++++ WDL +Q + Sbjct: 553 -HNEILVRQFQGHTDGASCIDISPDGSRLW-TGGLDNTVRSWDLREGRQLQQHDFSSQIF 610 Query: 407 SKQMLYCTCLSWSADG 454 S + YC W A G Sbjct: 611 S--LGYCPTGDWLAVG 624
>PK1IP_XENLA (Q68FJ6) p21-activated protein kinase-interacting protein 1-like| (PAK1-interacting protein 1-like) Length = 363 Score = 58.9 bits (141), Expect = 9e-09 Identities = 34/144 (23%), Positives = 67/144 (46%) Frame = +2 Query: 20 GWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCA 199 G ++C+ F N ++SG+ D + VWN + + T H G V ++++ P G L Sbjct: 81 GTITCLEFYGNTH---LLSGAEDGLICVWNTKKWECQQTFKAHKGQVLSLSIHPSGKLAL 137 Query: 200 SGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQ 379 S G D W+L EG+ + + + + +SP+ D++ ++ LE+ +V Sbjct: 138 SVGTDKTLRTWNLVEGRSAFIKNIKKNAHIVHWSPSGEKYVVVIHDTVDVYQLETAAVVG 197 Query: 380 DLRPEVPVSSKQMLYCTCLSWSAD 451 + +SS Q + ++ + D Sbjct: 198 TINNPKRISSAQFITDALIAVAGD 221
>POP3_SCHPO (O74184) WD-repeat protein pop3 (WD-repeat protein wat1)| Length = 314 Score = 58.9 bits (141), Expect = 9e-09 Identities = 38/127 (29%), Positives = 60/127 (47%), Gaps = 3/127 (2%) Frame = +2 Query: 134 TLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRY 313 T +GH V+A+A DG A+ +DG +WD+ + D S +N L PN+ Sbjct: 78 TFEGHTNNVTAIAFHCDGKWLATSSEDGTVKVWDMRAPSVQRNYDHKSPVNDLLIHPNQG 137 Query: 314 WLCAATQDS-IKIWDLESKHIVQDLRPE--VPVSSKQMLYCTCLSWSADGSTLYAGYTDG 484 L + Q ++ WDL +L PE VP+SS ++ +DGS L AG G Sbjct: 138 ELLSCDQSGRVRAWDLGENSCTHELIPEEDVPMSS--------ITVGSDGSMLIAGNNKG 189 Query: 485 TIRIYKI 505 ++++ Sbjct: 190 NCYVWRM 196 Score = 40.0 bits (92), Expect = 0.004 Identities = 25/104 (24%), Positives = 49/104 (47%), Gaps = 1/104 (0%) Frame = +2 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLD-AGSIINSLCFSPNRYWLCAATQDSIKIWDLESK 367 L S G D W+ G ++ A S +N LC SP++ +L AA ++++D+ + Sbjct: 12 LLVSSGYDHTIRFWEALSGICSRTIQHADSQVNRLCISPDKKFLAAAGNPHVRLYDINTS 71 Query: 368 HIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 + + E ++ T +++ DG L DGT++++ Sbjct: 72 SQMPLMTFEGHTNN-----VTAIAFHCDGKWLATSSEDGTVKVW 110 Score = 33.5 bits (75), Expect = 0.42 Identities = 22/80 (27%), Positives = 37/80 (46%), Gaps = 2/80 (2%) Frame = +2 Query: 80 SWDRSVKVWNLTNCK--LRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKR 253 S D +V +W+ + L L GH +V A S D + + D V LW+L+ G+ Sbjct: 234 SADATVNIWSTEDMSFMLERRLQGHQRWVWDCAFSADSTYLVTASSDHVARLWELSSGET 293 Query: 254 LYSLDAGSIINSLCFSPNRY 313 + +G ++C + N Y Sbjct: 294 IRQY-SGHHKAAVCVALNDY 312
>PRP46_YEAST (Q12417) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) (Complexed with CEF1 protein 1) (PRP19-associated complex protein 50) (PRP nineteen-associated complex protein 50) Length = 451 Score = 58.9 bits (141), Expect = 9e-09 Identities = 48/168 (28%), Positives = 80/168 (47%), Gaps = 3/168 (1%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G GWV CV P + ++GS D ++KVW+L KL+ TL GH V VAVS Sbjct: 137 GHLGWVRCVAIDPVD-NEWFITGSNDTTMKVWDLATGKLKTTLAGHVMTVRDVAVSDRHP 195 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAG-SIINSLCFSPNRYWLCAATQDS-IKIWDLES 364 S +D WDL + + + S + ++ P + A +DS IK+WD+ + Sbjct: 196 YLFSVSEDKTVKCWDLEKNQIIRDYYGHLSGVRTVSIHPTLDLIATAGRDSVIKLWDMRT 255 Query: 365 K-HIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 + ++ + + P++ Q CT + S+ TD T+R++ + Sbjct: 256 RIPVITLVGHKGPINQVQ---CTPVDPQVVSSS-----TDATVRLWDV 295 Score = 48.9 bits (115), Expect = 1e-05 Identities = 30/91 (32%), Positives = 48/91 (52%), Gaps = 4/91 (4%) Frame = +2 Query: 122 KLRCTLDGHGGYVSAVAVSP-DGSLCASGGKDGVTLLWDLTEGKRLYSLDAGSI--INSL 292 KL ++GH G+V VA+ P D +G D +WDL GK +L AG + + + Sbjct: 130 KLSRVINGHLGWVRCVAIDPVDNEWFITGSNDTTMKVWDLATGKLKTTL-AGHVMTVRDV 188 Query: 293 CFSPNRYWLCAATQD-SIKIWDLESKHIVQD 382 S +L + ++D ++K WDLE I++D Sbjct: 189 AVSDRHPYLFSVSEDKTVKCWDLEKNQIIRD 219 Score = 47.4 bits (111), Expect = 3e-05 Identities = 38/155 (24%), Positives = 63/155 (40%), Gaps = 2/155 (1%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 I + D +K+W++ TL GH G ++ V +P S D LWD+ G Sbjct: 239 IATAGRDSVIKLWDMRTRIPVITLVGHKGPINQVQCTPVDPQVVSSSTDATVRLWDVVAG 298 Query: 248 KRLYSLDAGS-IINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLY 424 K + L + + P + + +A D I+ W L ++ + S++ Sbjct: 299 KTMKVLTHHKRSVRATALHPKEFSVASACTDDIRSWGLAEGSLLTNF------ESEKTGI 352 Query: 425 CTCLSWSADGSTLYAGYTDGTIRIYKI-SGFSYSS 526 LS + D L+AG +G + Y SG Y S Sbjct: 353 INTLSINQD-DVLFAGGDNGVLSFYDYKSGHKYQS 386
>GBB3_TOBAC (Q40507) Guanine nucleotide-binding protein beta subunit| Length = 375 Score = 58.9 bits (141), Expect = 9e-09 Identities = 52/175 (29%), Positives = 76/175 (43%), Gaps = 8/175 (4%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVW-NLTNCKLRCTLDGHGGYVSAVAVSPDG 187 G T V V S +N VSGS D + ++W N + + T GH G V+ V PDG Sbjct: 202 GHTADVQSVSISSSN-PRLFVSGSCDTTARLWDNRVASRAQRTFYGHEGDVNTVKFFPDG 260 Query: 188 SLCASGGKDGVTLLWDLTEGKRL--YSLDAGS----IINSLCFS-PNRYWLCAATQDSIK 346 + +G +DG L+D+ G +L Y G + S+ FS R + Sbjct: 261 NRFGTGSEDGTCRLFDIRTGHQLQVYYQPHGDGDIPHVTSMAFSISGRLLFVGYSNGDCY 320 Query: 347 IWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISG 511 +WD +V +L V + +CL SADGS L G D ++I+ G Sbjct: 321 VWDTLLAKVVLNLG---GVQNSHEGRISCLGLSADGSALCTGSWDTNLKIWAFGG 372 Score = 47.0 bits (110), Expect = 4e-05 Identities = 47/188 (25%), Positives = 74/188 (39%), Gaps = 24/188 (12%) Frame = +2 Query: 14 PTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLT-------NCKLRCTLDGHGGYVSAVA 172 P WV FSP+ ++ G D ++NL N + L GH GYVS+ Sbjct: 106 PCAWVMTCAFSPSG--QSVACGGLDSVCSIYNLNSPIDKDGNHPVSRMLSGHKGYVSSCQ 163 Query: 173 VSPDGS--LCASGGKDGVTLLWDLTEGKRL----------YSLDAGSIINSLCFSPNRYW 316 PD L S G D +LWD+T G R ++ D S+ S+ S R + Sbjct: 164 YVPDEDTHLITSSG-DQTCVLWDITTGLRTSVFGGEFQSGHTADVQSV--SISSSNPRLF 220 Query: 317 LCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLY-----CTCLSWSADGSTLYAGYTD 481 + + + ++WD V +++ Y + + DG+ G D Sbjct: 221 VSGSCDTTARLWD-----------NRVASRAQRTFYGHEGDVNTVKFFPDGNRFGTGSED 269 Query: 482 GTIRIYKI 505 GT R++ I Sbjct: 270 GTCRLFDI 277 Score = 30.0 bits (66), Expect = 4.6 Identities = 20/88 (22%), Positives = 45/88 (51%), Gaps = 2/88 (2%) Frame = +2 Query: 107 NLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLDAG-SII 283 +L C++ L GH G V ++ +P+ + S +DG ++W+ ++ +++ + + Sbjct: 54 DLVCCRI---LQGHTGKVYSLDWTPEKNRIVSASQDGRLIVWNALTSQKTHAIKLPCAWV 110 Query: 284 NSLCFSPNRYWLCAATQDSI-KIWDLES 364 + FSP+ + DS+ I++L S Sbjct: 111 MTCAFSPSGQSVACGGLDSVCSIYNLNS 138
>PRP4_PONPY (Q5NVD0) U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60| kDa protein) (WD splicing factor Prp4) Length = 521 Score = 58.9 bits (141), Expect = 9e-09 Identities = 43/147 (29%), Positives = 67/147 (45%), Gaps = 2/147 (1%) Frame = +2 Query: 83 WDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYS 262 +DRS ++W+L + +GH V +A DGSL +GG D +WDL G+ + Sbjct: 342 YDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMF 401 Query: 263 LDAG-SIINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCL 436 L+ I + FSPN Y + + D + K+WDL + V + + Q L Sbjct: 402 LEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCV------YTIPAHQNLVTGVK 455 Query: 437 SWSADGSTLYAGYTDGTIRIYKISGFS 517 G+ L G D T +I+ G+S Sbjct: 456 FEPIHGNFLLTGAYDNTAKIWTHPGWS 482 Score = 48.5 bits (114), Expect = 1e-05 Identities = 32/124 (25%), Positives = 58/124 (46%), Gaps = 10/124 (8%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSL---- 193 +S FSPN+ + + W K+W++ +C L TL GH V A+ P ++ Sbjct: 233 ISYCHFSPNS--KMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDQ 290 Query: 194 ----CASGGKDGVTLLWDLTEGKRLYSLDAGSI-INSLCFSPNRYWLCAATQD-SIKIWD 355 AS DG LW L + + ++ ++ + + + P+ +L D S ++WD Sbjct: 291 KDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWD 350 Query: 356 LESK 367 LE++ Sbjct: 351 LEAQ 354 Score = 45.4 bits (106), Expect = 1e-04 Identities = 26/96 (27%), Positives = 48/96 (50%), Gaps = 3/96 (3%) Frame = +2 Query: 74 SGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKR 253 +G D +VW+L + L+GH + + SP+G A+G D +WDL + + Sbjct: 381 TGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRC 440 Query: 254 LYSLDA-GSIINSLCFSP--NRYWLCAATQDSIKIW 352 +Y++ A +++ + F P + L A ++ KIW Sbjct: 441 VYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIW 476 Score = 40.0 bits (92), Expect = 0.004 Identities = 24/71 (33%), Positives = 36/71 (50%), Gaps = 2/71 (2%) Frame = +2 Query: 26 VSCVRFSP--NNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCA 199 V+ V+F P NF +++G++D + K+W TL GH G V + +S DG L A Sbjct: 451 VTGVKFEPIHGNF---LLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIA 507 Query: 200 SGGKDGVTLLW 232 + D LW Sbjct: 508 TCSYDRTFKLW 518
>PRP4_HUMAN (O43172) U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60| kDa protein) (WD splicing factor Prp4) (hPrp4) Length = 522 Score = 58.9 bits (141), Expect = 9e-09 Identities = 43/147 (29%), Positives = 67/147 (45%), Gaps = 2/147 (1%) Frame = +2 Query: 83 WDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYS 262 +DRS ++W+L + +GH V +A DGSL +GG D +WDL G+ + Sbjct: 343 YDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMF 402 Query: 263 LDAG-SIINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCL 436 L+ I + FSPN Y + + D + K+WDL + V + + Q L Sbjct: 403 LEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCV------YTIPAHQNLVTGVK 456 Query: 437 SWSADGSTLYAGYTDGTIRIYKISGFS 517 G+ L G D T +I+ G+S Sbjct: 457 FEPIHGNFLLTGAYDNTAKIWTHPGWS 483 Score = 48.5 bits (114), Expect = 1e-05 Identities = 32/124 (25%), Positives = 58/124 (46%), Gaps = 10/124 (8%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSL---- 193 +S FSPN+ + + W K+W++ +C L TL GH V A+ P ++ Sbjct: 234 ISYCHFSPNS--KMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDP 291 Query: 194 ----CASGGKDGVTLLWDLTEGKRLYSLDAGSI-INSLCFSPNRYWLCAATQD-SIKIWD 355 AS DG LW L + + ++ ++ + + + P+ +L D S ++WD Sbjct: 292 KDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWD 351 Query: 356 LESK 367 LE++ Sbjct: 352 LEAQ 355 Score = 45.4 bits (106), Expect = 1e-04 Identities = 26/96 (27%), Positives = 48/96 (50%), Gaps = 3/96 (3%) Frame = +2 Query: 74 SGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKR 253 +G D +VW+L + L+GH + + SP+G A+G D +WDL + + Sbjct: 382 TGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRC 441 Query: 254 LYSLDA-GSIINSLCFSP--NRYWLCAATQDSIKIW 352 +Y++ A +++ + F P + L A ++ KIW Sbjct: 442 VYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIW 477 Score = 40.0 bits (92), Expect = 0.004 Identities = 24/71 (33%), Positives = 36/71 (50%), Gaps = 2/71 (2%) Frame = +2 Query: 26 VSCVRFSP--NNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCA 199 V+ V+F P NF +++G++D + K+W TL GH G V + +S DG L A Sbjct: 452 VTGVKFEPIHGNF---LLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIA 508 Query: 200 SGGKDGVTLLW 232 + D LW Sbjct: 509 TCSYDRTFKLW 519
>TUP1_CANAL (P56093) Transcriptional repressor TUP1| Length = 514 Score = 58.5 bits (140), Expect = 1e-08 Identities = 36/166 (21%), Positives = 81/166 (48%), Gaps = 1/166 (0%) Frame = +2 Query: 23 WVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCAS 202 ++ V FSP+ + +G+ D+ +++W+L+ ++ L GH + ++ PDG S Sbjct: 259 YIRSVCFSPDG--KLLATGAEDKLIRIWDLSTKRIIKILRGHEQDIYSLDFFPDGDRLVS 316 Query: 203 GGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQ 379 G D +WDL + +L + ++ SP+ + A + D ++++WD + +V+ Sbjct: 317 GSGDRSVRIWDLRTSQCSLTLSIEDGVTTVAVSPDGKLIAAGSLDRTVRVWDSTTGFLVE 376 Query: 380 DLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISGFS 517 L + +++S +G + +G D T++++ + G S Sbjct: 377 RLDSGNENGNGHEDSVYSVAFSNNGEQIASGSLDRTVKLWHLEGKS 422 Score = 48.9 bits (115), Expect = 1e-05 Identities = 33/85 (38%), Positives = 42/85 (49%), Gaps = 5/85 (5%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNL---TNCKLRC--TLDGHGGYVSAVAVSPDGS 190 V V FS N I SGS DR+VK+W+L ++ K C T GH +V +V +PD Sbjct: 392 VYSVAFSNNG--EQIASGSLDRTVKLWHLEGKSDKKSTCEVTYIGHKDFVLSVCCTPDNE 449 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSL 265 SG KD + WD G L L Sbjct: 450 YILSGSKDRGVIFWDQASGNPLLML 474 Score = 31.6 bits (70), Expect = 1.6 Identities = 26/82 (31%), Positives = 38/82 (46%), Gaps = 4/82 (4%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG- 187 G +V V +P+N I+SGS DR V W+ + L GH V +VAVS + Sbjct: 434 GHKDFVLSVCCTPDN--EYILSGSKDRGVIFWDQASGNPLLMLQGHRNSVISVAVSLNSK 491 Query: 188 ---SLCASGGKDGVTLLWDLTE 244 + A+G D +W T+ Sbjct: 492 GTEGIFATGSGDCKARIWKWTK 513 Score = 31.2 bits (69), Expect = 2.1 Identities = 22/92 (23%), Positives = 43/92 (46%), Gaps = 7/92 (7%) Frame = +2 Query: 254 LYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQM----- 418 ++SLD S++ + FS + ++ + +++++ + +V L E +K Sbjct: 196 VHSLDHSSVVCCVRFSRDGKFIATGCNKTTQVFNVTTGELVAKLIDESSNENKDDNTTAS 255 Query: 419 --LYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 LY + +S DG L G D IRI+ +S Sbjct: 256 GDLYIRSVCFSPDGKLLATGAEDKLIRIWDLS 287
>UTP15_HUMAN (Q8TED0) U3 small nucleolar RNA-associated protein 15 homolog| Length = 518 Score = 58.5 bits (140), Expect = 1e-08 Identities = 45/170 (26%), Positives = 79/170 (46%), Gaps = 10/170 (5%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVS---AVAVSPDGSLCASGGKDGVTLLWDL 238 +VSG+ D +VK+W++ N K T H YV A ++PD L +G D ++D Sbjct: 137 VVSGADDYTVKLWDIPNSKEILTFKEHSDYVRCGCASKLNPD--LFITGSYDHTVKMFDA 194 Query: 239 TEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWD-LESKHIVQDLRPEVPVSSKQ 415 + + S++ G + S+ P+ L +A +K+WD L+ ++ L+ Sbjct: 195 RTSESVLSVEHGQPVESVLLFPSGGLLVSAGGRYVKVWDMLKGGQLLVSLKNHHKT---- 250 Query: 416 MLYCTCLSWSADGSTLYAGYTDGTIRIYK------ISGFSYSS*IMYLVL 547 TCL S+ G L +G D +++Y + F Y++ I+ L L Sbjct: 251 ---VTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSFDYAASILSLAL 297
>PRP4_MOUSE (Q9DAW6) U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60| kDa protein) (WD splicing factor Prp4) Length = 521 Score = 58.5 bits (140), Expect = 1e-08 Identities = 43/147 (29%), Positives = 66/147 (44%), Gaps = 2/147 (1%) Frame = +2 Query: 83 WDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYS 262 +DRS ++W+L + +GH V +A DGSL +GG D +WDL G+ + Sbjct: 342 YDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMF 401 Query: 263 LDAG-SIINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCL 436 L+ I + FSPN Y + + D + K+WDL + V + + Q L Sbjct: 402 LEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCV------YTIPAHQNLVTGVK 455 Query: 437 SWSADGSTLYAGYTDGTIRIYKISGFS 517 G L G D T +I+ G+S Sbjct: 456 FEPIHGDFLLTGAYDNTAKIWTHPGWS 482 Score = 48.5 bits (114), Expect = 1e-05 Identities = 32/124 (25%), Positives = 58/124 (46%), Gaps = 10/124 (8%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSL---- 193 +S FSPN+ + + W K+W++ +C L TL GH V A+ P ++ Sbjct: 233 ISYCHFSPNS--KMLATACWSGLCKLWSVPDCSLLHTLRGHNTNVGAIVFHPKSTVSLDQ 290 Query: 194 ----CASGGKDGVTLLWDLTEGKRLYSLDAGSI-INSLCFSPNRYWLCAATQD-SIKIWD 355 AS DG LW L + + ++ ++ + + + P+ +L D S ++WD Sbjct: 291 KDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWD 350 Query: 356 LESK 367 LE++ Sbjct: 351 LEAQ 354 Score = 44.7 bits (104), Expect = 2e-04 Identities = 26/96 (27%), Positives = 48/96 (50%), Gaps = 3/96 (3%) Frame = +2 Query: 74 SGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKR 253 +G D +VW+L + L+GH + + SP+G A+G D +WDL + + Sbjct: 381 TGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRC 440 Query: 254 LYSLDA-GSIINSLCFSP--NRYWLCAATQDSIKIW 352 +Y++ A +++ + F P + L A ++ KIW Sbjct: 441 VYTIPAHQNLVTGVKFEPIHGDFLLTGAYDNTAKIW 476 Score = 39.3 bits (90), Expect = 0.008 Identities = 22/69 (31%), Positives = 35/69 (50%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 V+ V+F P + +++G++D + K+W TL GH G V + +S DG L A+ Sbjct: 451 VTGVKFEPIH-GDFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATC 509 Query: 206 GKDGVTLLW 232 D LW Sbjct: 510 SYDRTFKLW 518
>WDR31_HUMAN (Q8NA23) WD-repeat protein 31| Length = 367 Score = 58.5 bits (140), Expect = 1e-08 Identities = 35/113 (30%), Positives = 60/113 (53%), Gaps = 3/113 (2%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLT-NCKLRCTLDGHGGYVSAVAVSPDGSLCAS 202 V+C+ S F S S DR V +W+L + + R L GH V+ +AVSPD S + Sbjct: 109 VACIPKSSQFF-----SASRDRMVMMWDLHGSSQPRQQLCGHAMVVTGLAVSPDSSQLCT 163 Query: 203 GGKDGVTLLWDLTEGKRLYSLDAG-SIINSLCFSPNRYWLCAATQD-SIKIWD 355 G +D LLWD+ G+ + +++ LC+ P ++ ++D ++++WD Sbjct: 164 GSRDNTLLLWDVVTGQSVERASVSRNVVTHLCWVPREPYILQTSEDKTLRLWD 216 Score = 43.1 bits (100), Expect = 5e-04 Identities = 27/106 (25%), Positives = 49/106 (46%), Gaps = 3/106 (2%) Frame = +2 Query: 71 VSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL--TE 244 VSG D++V +N + GH ++ VA P S S +D + ++WDL + Sbjct: 77 VSGGKDKTVVAYNWKTGNVVKRFKGHEHEITKVACIPKSSQFFSASRDRMVMMWDLHGSS 136 Query: 245 GKRLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQ 379 R ++ L SP+ LC ++D ++ +WD+ + V+ Sbjct: 137 QPRQQLCGHAMVVTGLAVSPDSSQLCTGSRDNTLLLWDVVTGQSVE 182 Score = 35.4 bits (80), Expect = 0.11 Identities = 29/85 (34%), Positives = 36/85 (42%), Gaps = 4/85 (4%) Frame = +2 Query: 29 SCVRFSPNNFA--PTIVSGSWDRSVKVWNLTN--CKLRCTLDGHGGYVSAVAVSPDGSLC 196 SCV F P A P I + S D VK+WN C +LDG G S LC Sbjct: 283 SCV-FLPRALALMPLIATSSHDCKVKIWNQDTGACLFTLSLDGSGPLTSLAVGDAISLLC 341 Query: 197 ASGGKDGVTLLWDLTEGKRLYSLDA 271 AS + L D ++G L + A Sbjct: 342 ASFNRGIHLLRMDHSQGLELQEVAA 366 Score = 34.7 bits (78), Expect = 0.19 Identities = 30/122 (24%), Positives = 49/122 (40%), Gaps = 2/122 (1%) Frame = +2 Query: 146 HGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGK--RLYSLDAGSIINSLCFSPNRYWL 319 H VS VA + LC SGGKD + ++ G + + I C + + Sbjct: 61 HMDTVSVVAAL-NSDLCVSGGKDKTVVAYNWKTGNVVKRFKGHEHEITKVACIPKSSQFF 119 Query: 320 CAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 A+ + +WDL +P + M+ T L+ S D S L G D T+ ++ Sbjct: 120 SASRDRMVMMWDLHGSS-----QPRQQLCGHAMV-VTGLAVSPDSSQLCTGSRDNTLLLW 173 Query: 500 KI 505 + Sbjct: 174 DV 175
>GBB5_HUMAN (O14775) Guanine nucleotide-binding protein beta subunit 5| (Transducin beta chain 5) (Gbeta5) Length = 395 Score = 58.2 bits (139), Expect = 2e-08 Identities = 42/169 (24%), Positives = 87/169 (51%), Gaps = 6/169 (3%) Frame = +2 Query: 17 TGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPD--GS 190 T ++S F+ ++ I++ S D + +W++ + +L + GHG V + ++P G+ Sbjct: 195 TNYLSACSFTNSDMQ--ILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGN 252 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAG-SIINSLCFSPNRYWLCAATQDSI-KIWDLES 364 SGG D ++WD+ G+ + + + S INS+ + P+ + + D+ +++DL + Sbjct: 253 TFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRA 312 Query: 365 KHIVQDLRPEVPVSSKQMLY--CTCLSWSADGSTLYAGYTDGTIRIYKI 505 EV + SK+ + + + +S G L+AGY D TI ++ + Sbjct: 313 DR-------EVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDV 354 Score = 54.3 bits (129), Expect = 2e-07 Identities = 42/162 (25%), Positives = 74/162 (45%), Gaps = 4/162 (2%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 V C+ +P+ T VSG D+ VW++ + + + H +++V P G ASG Sbjct: 240 VLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASG 299 Query: 206 GKDGVTLLWDLTEGKRLYSLDAGSII---NSLCFSPNRYWLCAATQD-SIKIWDLESKHI 373 D L+DL + + SII +S+ FS + L A D +I +WD + Sbjct: 300 SDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWD-----V 354 Query: 374 VQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 ++ R + + + + L S DG+ +G D T+R++ Sbjct: 355 LKGSRVSILFGHENRV--STLRVSPDGTAFCSGSWDHTLRVW 394
>MORG1_HUMAN (Q9BRX9) Mitogen-activated protein kinase organizer 1 (MAPK| organizer 1) Length = 315 Score = 58.2 bits (139), Expect = 2e-08 Identities = 53/166 (31%), Positives = 77/166 (46%), Gaps = 4/166 (2%) Frame = +2 Query: 20 GWVSCVRFSPN-NFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLC 196 G V VRF+ + N+ T S D+++K+WN L T GHG V A S D S Sbjct: 26 GAVRAVRFNVDGNYCLTCGS---DKTLKLWNPLRGTLLRTYSGHGYEVLDAAGSFDNSSL 82 Query: 197 ASGGKDGVTLLWDLTEGK--RLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLESK 367 SGG D +LWD+ G+ R + AG +N++ F+ + + + D SI+ WD S+ Sbjct: 83 CSGGGDKAVVLWDVASGQVVRKFRGHAGK-VNTVQFNEEATVILSGSIDSSIRCWDCRSR 141 Query: 368 HIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 RPE PV + S + AG DG +R Y + Sbjct: 142 ------RPE-PVQTLDEARDGVSSVKVSDHEILAGSVDGRVRRYDL 180 Score = 38.1 bits (87), Expect = 0.017 Identities = 32/116 (27%), Positives = 52/116 (44%), Gaps = 3/116 (2%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGG--YVSAVAVSPDGSLCA 199 ++C FS + T+VS S D ++++ + +L GH Y +S + Sbjct: 194 ITCTCFSRDGQC-TLVS-SLDSTLRLLDKDTGELLGEYKGHKNQEYKLDCCLSERDTHVV 251 Query: 200 SGGKDGVTLLWDLTEGKRLYSLDAGS-IINSLCFSPNRYWLCAATQDSIKIWDLES 364 S +DG WDL EG +L GS ++ SL + P L A S++ W E+ Sbjct: 252 SCSEDGKVFFWDLVEGALALALPVGSGVVQSLAYHPTEPCLLTAMGGSVQCWREEA 307 Score = 37.7 bits (86), Expect = 0.022 Identities = 28/124 (22%), Positives = 51/124 (41%), Gaps = 2/124 (1%) Frame = +2 Query: 134 TLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGK--RLYSLDAGSIINSLCFSPN 307 TLD G V AV + DG+ C + G D LW+ G R YS ++++ N Sbjct: 20 TLDCGQGAVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGTLLRTYSGHGYEVLDAAGSFDN 79 Query: 308 RYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGT 487 ++ +WD+ S +V+ R + ++ + + + +G D + Sbjct: 80 SSLCSGGGDKAVVLWDVASGQVVRKFRGHAG-------KVNTVQFNEEATVILSGSIDSS 132 Query: 488 IRIY 499 IR + Sbjct: 133 IRCW 136
>WDR48_MOUSE (Q8BH57) WD-repeat protein 48| Length = 676 Score = 58.2 bits (139), Expect = 2e-08 Identities = 47/174 (27%), Positives = 76/174 (43%), Gaps = 11/174 (6%) Frame = +2 Query: 17 TGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLC 196 T WV+ V N T++S S D +VKVWN TL H YV A+A + D L Sbjct: 75 TDWVNDVVLCCNG--KTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELV 132 Query: 197 ASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCA-----------ATQDSI 343 AS G D LWD+ L + + +SL + + + A +T+ + Sbjct: 133 ASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVL 192 Query: 344 KIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 ++WD + + L+ +L+ DG+ +G +DGTIR++ + Sbjct: 193 RVWDPRTCAKLMKLKGHTDNVKALLLH-------RDGTQCLSGSSDGTIRLWSL 239
>GBB5_TAMST (Q80ZD0) Guanine nucleotide-binding protein beta subunit 5| (Transducin beta chain 5) (Gbeta5) Length = 353 Score = 58.2 bits (139), Expect = 2e-08 Identities = 42/169 (24%), Positives = 87/169 (51%), Gaps = 6/169 (3%) Frame = +2 Query: 17 TGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPD--GS 190 T ++S F+ ++ I++ S D + +W++ + +L + GHG V + ++P G+ Sbjct: 153 TNYLSACSFTNSDMQ--ILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGN 210 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAG-SIINSLCFSPNRYWLCAATQDSI-KIWDLES 364 SGG D ++WD+ G+ + + + S INS+ + P+ + + D+ +++DL + Sbjct: 211 TFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRA 270 Query: 365 KHIVQDLRPEVPVSSKQMLY--CTCLSWSADGSTLYAGYTDGTIRIYKI 505 EV + SK+ + + + +S G L+AGY D TI ++ + Sbjct: 271 DR-------EVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDV 312 Score = 54.3 bits (129), Expect = 2e-07 Identities = 42/162 (25%), Positives = 74/162 (45%), Gaps = 4/162 (2%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 V C+ +P+ T VSG D+ VW++ + + + H +++V P G ASG Sbjct: 198 VLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASG 257 Query: 206 GKDGVTLLWDLTEGKRLYSLDAGSII---NSLCFSPNRYWLCAATQD-SIKIWDLESKHI 373 D L+DL + + SII +S+ FS + L A D +I +WD + Sbjct: 258 SDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWD-----V 312 Query: 374 VQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 ++ R + + + + L S DG+ +G D T+R++ Sbjct: 313 LKGSRVSILFGHENRV--STLRVSPDGTAFCSGSWDHTLRVW 352
>GBB5_RABIT (Q6PNB6) Guanine nucleotide-binding protein beta subunit 5| (Transducin beta chain 5) (Gbeta5) Length = 353 Score = 58.2 bits (139), Expect = 2e-08 Identities = 42/169 (24%), Positives = 87/169 (51%), Gaps = 6/169 (3%) Frame = +2 Query: 17 TGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPD--GS 190 T ++S F+ ++ I++ S D + +W++ + +L + GHG V + ++P G+ Sbjct: 153 TNYLSACSFTNSDMQ--ILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGN 210 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAG-SIINSLCFSPNRYWLCAATQDSI-KIWDLES 364 SGG D ++WD+ G+ + + + S INS+ + P+ + + D+ +++DL + Sbjct: 211 TFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRA 270 Query: 365 KHIVQDLRPEVPVSSKQMLY--CTCLSWSADGSTLYAGYTDGTIRIYKI 505 EV + SK+ + + + +S G L+AGY D TI ++ + Sbjct: 271 DR-------EVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDV 312 Score = 54.7 bits (130), Expect = 2e-07 Identities = 42/162 (25%), Positives = 74/162 (45%), Gaps = 4/162 (2%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 V C+ +P+ T VSG D+ VW++ + + + H +++V P G ASG Sbjct: 198 VLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASG 257 Query: 206 GKDGVTLLWDLTEGKRLYSLDAGSII---NSLCFSPNRYWLCAATQD-SIKIWDLESKHI 373 D L+DL + + SII +S+ FS + L A D +I +WD + Sbjct: 258 SDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWD-----V 312 Query: 374 VQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 ++ R + + + + L S DG+ +G D T+R++ Sbjct: 313 LKGARVSILFGHENRV--STLRVSPDGTAFCSGSWDHTLRVW 352
>GBB5_PONPY (Q5RDY7) Guanine nucleotide-binding protein beta subunit 5| (Transducin beta chain 5) (Gbeta5) Length = 353 Score = 58.2 bits (139), Expect = 2e-08 Identities = 42/169 (24%), Positives = 87/169 (51%), Gaps = 6/169 (3%) Frame = +2 Query: 17 TGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPD--GS 190 T ++S F+ ++ I++ S D + +W++ + +L + GHG V + ++P G+ Sbjct: 153 TNYLSACSFTNSDMQ--ILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGN 210 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAG-SIINSLCFSPNRYWLCAATQDSI-KIWDLES 364 SGG D ++WD+ G+ + + + S INS+ + P+ + + D+ +++DL + Sbjct: 211 TFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRA 270 Query: 365 KHIVQDLRPEVPVSSKQMLY--CTCLSWSADGSTLYAGYTDGTIRIYKI 505 EV + SK+ + + + +S G L+AGY D TI ++ + Sbjct: 271 DR-------EVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDV 312 Score = 54.3 bits (129), Expect = 2e-07 Identities = 42/162 (25%), Positives = 74/162 (45%), Gaps = 4/162 (2%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 V C+ +P+ T VSG D+ VW++ + + + H +++V P G ASG Sbjct: 198 VLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASG 257 Query: 206 GKDGVTLLWDLTEGKRLYSLDAGSII---NSLCFSPNRYWLCAATQD-SIKIWDLESKHI 373 D L+DL + + SII +S+ FS + L A D +I +WD + Sbjct: 258 SDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWD-----V 312 Query: 374 VQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 ++ R + + + + L S DG+ +G D T+R++ Sbjct: 313 LKGSRVSILFGHENRV--STLRVSPDGTAFCSGSWDHTLRVW 352
>GBB_SCHPO (Q10282) Guanine nucleotide-binding protein beta subunit| Length = 305 Score = 58.2 bits (139), Expect = 2e-08 Identities = 43/159 (27%), Positives = 76/159 (47%), Gaps = 3/159 (1%) Frame = +2 Query: 44 SPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVT 223 +PN F V+G D+ K+W+L T G+ +++++ P + +G +DG+ Sbjct: 159 NPNLF----VTGGCDKLAKLWDLRAAYCCATFPGNTSDINSISFFPSNADFVTGAEDGIA 214 Query: 224 LLWDLTEGKRL--YSLDAGSIINSLCFSPNRYWLCAATQDSIKIWD-LESKHIVQDLRPE 394 +D+ + YS + S INS+ FS + L A + ++WD + SK I E Sbjct: 215 RCFDIRASAEIFQYSSPSSSPINSVLFSKSGKLLFIAKDKTCEVWDSISSKTITSLTGHE 274 Query: 395 VPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISG 511 +SS L+ ++DG+ L G D +R++ SG Sbjct: 275 NRISS--------LALTSDGTMLATGSWDECVRLWSSSG 305 Score = 30.4 bits (67), Expect = 3.6 Identities = 16/53 (30%), Positives = 27/53 (50%), Gaps = 1/53 (1%) Frame = +2 Query: 152 GYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLDAGSI-INSLCFSPN 307 G + + +S DG S + V L+WDL ++ +A S+ I + FSP+ Sbjct: 22 GKIPDIDISTDGKYLLSASTNDVLLVWDLHTSNKVAFFEAPSVWIMTCAFSPS 74
>GBB5_MOUSE (P62881) Guanine nucleotide-binding protein beta subunit 5| (Transducin beta chain 5) (Gbeta5) Length = 395 Score = 57.8 bits (138), Expect = 2e-08 Identities = 41/169 (24%), Positives = 87/169 (51%), Gaps = 6/169 (3%) Frame = +2 Query: 17 TGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPD--GS 190 T ++S F+ ++ I++ S D + +W++ + +L + GHG V + ++P G+ Sbjct: 195 TNYLSACSFTNSDMQ--ILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGN 252 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAG-SIINSLCFSPNRYWLCAATQDSI-KIWDLES 364 SGG D ++WD+ G+ + + + S +NS+ + P+ + + D+ +++DL + Sbjct: 253 TFVSGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRYYPSGDAFASGSDDATCRLYDLRA 312 Query: 365 KHIVQDLRPEVPVSSKQMLY--CTCLSWSADGSTLYAGYTDGTIRIYKI 505 EV + SK+ + + + +S G L+AGY D TI ++ + Sbjct: 313 DR-------EVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDV 354 Score = 54.7 bits (130), Expect = 2e-07 Identities = 43/162 (26%), Positives = 74/162 (45%), Gaps = 4/162 (2%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 V C+ +P+ T VSG D+ VW++ + + + H V++V P G ASG Sbjct: 240 VLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRYYPSGDAFASG 299 Query: 206 GKDGVTLLWDLTEGKRLYSLDAGSII---NSLCFSPNRYWLCAATQD-SIKIWDLESKHI 373 D L+DL + + SII +S+ FS + L A D +I +WD + Sbjct: 300 SDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWD-----V 354 Query: 374 VQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 ++ R + + + + L S DG+ +G D T+R++ Sbjct: 355 LKGSRVSILFGHENRV--STLRVSPDGTAFCSGSWDHTLRVW 394
>POP2_SCHPO (O14170) WD-repeat protein pop2 (Proteolysis factor sud1)| Length = 703 Score = 57.8 bits (138), Expect = 2e-08 Identities = 28/105 (26%), Positives = 52/105 (49%) Frame = +2 Query: 50 NNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLL 229 + + +VSGS+D S+++W ++ + L GH + +V P+ ++C SG D + Sbjct: 514 SGYGDILVSGSYDSSIRIWRVSTGECLYHLRGHSLRIYSVLYEPERNICISGSMDKSIRV 573 Query: 230 WDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLES 364 WDL+ G Y L+ +L + + +I+IWDL + Sbjct: 574 WDLSTGTCKYVLEGHDAFVTLLNVFQNRLISGSADSTIRIWDLNT 618 Score = 45.8 bits (107), Expect = 8e-05 Identities = 49/174 (28%), Positives = 77/174 (44%), Gaps = 25/174 (14%) Frame = +2 Query: 62 PTIVSGSWDRSVKVWNL------------TNCKLRC--------TLDGHGGYVSAVAVSP 181 P IVSGS D +++VW L TN R TL GH S +S Sbjct: 458 PYIVSGSRDHTLRVWKLPKNTDPPYLPDNTNSIDRWEKNPYFVHTLIGHTD--SVRTISG 515 Query: 182 DGSLCASGGKDGVTLLWDLTEGKRLYSLDAGSI-INSLCFSPNRYWLCAATQD-SIKIWD 355 G + SG D +W ++ G+ LY L S+ I S+ + P R + + D SI++WD Sbjct: 516 YGDILVSGSYDSSIRIWRVSTGECLYHLRGHSLRIYSVLYEPERNICISGSMDKSIRVWD 575 Query: 356 LES---KHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 L + K++++ + T L + + L +G D TIRI+ ++ Sbjct: 576 LSTGTCKYVLEG----------HDAFVTLL--NVFQNRLISGSADSTIRIWDLN 617 Score = 43.9 bits (102), Expect = 3e-04 Identities = 24/69 (34%), Positives = 38/69 (55%) Frame = +2 Query: 50 NNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLL 229 N F ++SGS D ++++W+L K L + GY+S+ VS + + + G DG L Sbjct: 596 NVFQNRLISGSADSTIRIWDLNTGKPLMVLPSNSGYISSF-VSDEHKIIS--GNDGSVKL 652 Query: 230 WDLTEGKRL 256 WD+ GK L Sbjct: 653 WDVRTGKLL 661 Score = 36.2 bits (82), Expect = 0.065 Identities = 21/72 (29%), Positives = 30/72 (41%), Gaps = 14/72 (19%) Frame = +2 Query: 65 TIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAV--------------AVSPDGSLCAS 202 T+VSGS D++V+VWN+ K GH + + V PD S Sbjct: 403 TLVSGSIDKTVRVWNIEKAKCTHIFRGHISIIRCLEILVPSRLIRHGVEIVEPDQPYIVS 462 Query: 203 GGKDGVTLLWDL 238 G +D +W L Sbjct: 463 GSRDHTLRVWKL 474
>CWF8_SCHPO (O14011) Cell cycle control protein cwf8| Length = 488 Score = 57.8 bits (138), Expect = 2e-08 Identities = 34/107 (31%), Positives = 56/107 (52%), Gaps = 3/107 (2%) Frame = +2 Query: 155 YVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAAT 331 +++++AV PDG+L +G ++G ++ + G L S + +L F N YWL T Sbjct: 335 HITSLAVHPDGNLFVAGLENGELRFFETSSGNELTKFGPHSSPVKTLQFGENGYWLVVTT 394 Query: 332 QDS--IKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLY 466 D I IWDL +VQ + + V++ + + L S+DG TLY Sbjct: 395 NDDSDIFIWDLRKSELVQKIPLQTKVAAVSLDITSQLLVSSDGETLY 441
>GBB5_RAT (P62882) Guanine nucleotide-binding protein beta subunit 5| (Transducin beta chain 5) (Gbeta5) Length = 353 Score = 57.8 bits (138), Expect = 2e-08 Identities = 41/169 (24%), Positives = 87/169 (51%), Gaps = 6/169 (3%) Frame = +2 Query: 17 TGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPD--GS 190 T ++S F+ ++ I++ S D + +W++ + +L + GHG V + ++P G+ Sbjct: 153 TNYLSACSFTNSDMQ--ILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGN 210 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAG-SIINSLCFSPNRYWLCAATQDSI-KIWDLES 364 SGG D ++WD+ G+ + + + S +NS+ + P+ + + D+ +++DL + Sbjct: 211 TFVSGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRYYPSGDAFASGSDDATCRLYDLRA 270 Query: 365 KHIVQDLRPEVPVSSKQMLY--CTCLSWSADGSTLYAGYTDGTIRIYKI 505 EV + SK+ + + + +S G L+AGY D TI ++ + Sbjct: 271 DR-------EVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDV 312 Score = 54.7 bits (130), Expect = 2e-07 Identities = 43/162 (26%), Positives = 74/162 (45%), Gaps = 4/162 (2%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 V C+ +P+ T VSG D+ VW++ + + + H V++V P G ASG Sbjct: 198 VLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRYYPSGDAFASG 257 Query: 206 GKDGVTLLWDLTEGKRLYSLDAGSII---NSLCFSPNRYWLCAATQD-SIKIWDLESKHI 373 D L+DL + + SII +S+ FS + L A D +I +WD + Sbjct: 258 SDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWD-----V 312 Query: 374 VQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 ++ R + + + + L S DG+ +G D T+R++ Sbjct: 313 LKGSRVSILFGHENRV--STLRVSPDGTAFCSGSWDHTLRVW 352
>WDR48_BRARE (Q6PFM9) WD-repeat protein 48| Length = 677 Score = 57.8 bits (138), Expect = 2e-08 Identities = 46/167 (27%), Positives = 74/167 (44%), Gaps = 4/167 (2%) Frame = +2 Query: 17 TGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLC 196 T WV+ + N T++S S D +VKVWN TL H YV A+A + D L Sbjct: 75 TDWVNDIILCCNG--KTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELV 132 Query: 197 ASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIV 376 AS G D LWD+ L + + +SL + + + A Q I ++ ++ Sbjct: 133 ASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQTGTVIISGSTEKVL 192 Query: 377 QDLRPEVPVSSKQMLYCT----CLSWSADGSTLYAGYTDGTIRIYKI 505 + P ++ T L + DG+ +G +DGTIR++ + Sbjct: 193 RVWDPRTCAKLMKLKGHTDNVKSLLLNRDGTQCLSGSSDGTIRLWSL 239
>TEP1_HUMAN (Q99973) Telomerase protein component 1 (Telomerase-associated| protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog) Length = 2627 Score = 57.8 bits (138), Expect = 2e-08 Identities = 45/166 (27%), Positives = 68/166 (40%), Gaps = 2/166 (1%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 ++CV F P I +GSW S+ + + K+ L G + +A + G + A G Sbjct: 1803 LNCVAFHPEG--QVIATGSWAGSISFFQVDGLKVTKDLGAPGASIRTLAFNVPGGVVAVG 1860 Query: 206 GKDGVTLLWDLTEGKRLYSLDA--GSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQ 379 D + LW EG RL + A G + +L L A +++W Sbjct: 1861 RLDSMVELWAWREGARLAAFPAHHGFVAAALFLHAGCQLLTAGEDGKVQVWSGSLG---- 1916 Query: 380 DLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISGFS 517 RP + S + ++ S DG + GY IRIYKIS S Sbjct: 1917 --RPRGHLGSLSLSPALSVALSPDGDRVAVGYRADGIRIYKISSGS 1960 Score = 47.0 bits (110), Expect = 4e-05 Identities = 37/148 (25%), Positives = 64/148 (43%), Gaps = 10/148 (6%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 +++ S D SV++W + + V+AVA +PDGS+ SG + G +LW E Sbjct: 2253 MLTASEDGSVRLWQVPKEADDTCIPRSSAAVTAVAWAPDGSMAVSGNQAGELILWQ--EA 2310 Query: 248 KRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLE----------SKHIVQDLRPEV 397 K + + A I +L +S + + + I W ++ S H+ + L+ ++ Sbjct: 2311 KAVATAQAPGHIGALIWSSAHTFFVLSADEKISEWQVKLRKGSAPGNLSLHLNRILQEDL 2370 Query: 398 PVSSKQMLYCTCLSWSADGSTLYAGYTD 481 V T L W+ DG L D Sbjct: 2371 GV-------LTSLDWAPDGHFLILAKAD 2391 Score = 40.4 bits (93), Expect = 0.003 Identities = 32/113 (28%), Positives = 54/113 (47%), Gaps = 6/113 (5%) Frame = +2 Query: 137 LDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKR---LYSLDA--GSIINSLCFS 301 L GH G VS + S DG A+GG+D L WD+ K ++S A + ++ Sbjct: 2057 LRGHEGPVSCCSFSTDGGSLATGGRDRSLLCWDVRTPKTPVLIHSFPACHRDWVTGCAWT 2116 Query: 302 PNRYWLCAATQDSIKIWDLES-KHIVQDLRPEVPVSSKQMLYCTCLSWSADGS 457 + + ++ S+ +WD ES + + Q L + VS+ + +S S DG+ Sbjct: 2117 KDNLLISCSSDGSVGLWDPESGQRLGQFLGHQSAVSAVAAVEEHVVSVSRDGT 2169 Score = 37.4 bits (85), Expect = 0.029 Identities = 38/156 (24%), Positives = 72/156 (46%), Gaps = 11/156 (7%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVS--AVAVSPDGS-------LCASGGKDGV 220 +VS S D ++KVW+ +L ++ H G +S A A+ P + L + G DG Sbjct: 2161 VVSVSRDGTLKVWDHQGVELT-SIPAHSGPISHCAAAMEPRAAGQPGSELLVVTVGLDGA 2219 Query: 221 TLLWDLTEGKRLYSL--DAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPE 394 T LW + ++L +G + + + L A+ S+++W + + D Sbjct: 2220 TRLWHPLLVCQTHTLLGHSGPVRAAAVSETSGLMLTASEDGSVRLWQVPKE--ADDTC-- 2275 Query: 395 VPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYK 502 +P SS + T ++W+ DGS +G G + +++ Sbjct: 2276 IPRSSAAV---TAVAWAPDGSMAVSGNQAGELILWQ 2308 Score = 33.9 bits (76), Expect = 0.32 Identities = 30/147 (20%), Positives = 63/147 (42%), Gaps = 2/147 (1%) Frame = +2 Query: 65 TIVSGSWDRSVKVWNLTN-CKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLT 241 T+ ++D +++W+L + C++ T H ++ +SPD L A+ G LWD Sbjct: 1731 TLFLTAFDGLLELWDLQHGCRVLQT-KAHQYQITGCCLSPDCRLLATVCLGGCLKLWDTV 1789 Query: 242 EGKRLYSLDAGSIINSLCFSPNRYWLCAAT-QDSIKIWDLESKHIVQDLRPEVPVSSKQM 418 G+ + +N + F P + + SI + ++ + +DL P +S Sbjct: 1790 RGQLAFQHTYPKSLNCVAFHPEGQVIATGSWAGSISFFQVDGLKVTKDL--GAPGAS--- 1844 Query: 419 LYCTCLSWSADGSTLYAGYTDGTIRIY 499 L+++ G + G D + ++ Sbjct: 1845 --IRTLAFNVPGGVVAVGRLDSMVELW 1869
>WDR48_CHICK (Q5F3K4) WD-repeat protein 48| Length = 678 Score = 57.4 bits (137), Expect = 3e-08 Identities = 46/167 (27%), Positives = 74/167 (44%), Gaps = 4/167 (2%) Frame = +2 Query: 17 TGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLC 196 T WV+ + N T++S S D +VKVWN TL H YV A+A + D L Sbjct: 75 TDWVNDIVLCCNG--KTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELV 132 Query: 197 ASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIV 376 AS G D LWD+ L + + +SL + + + A Q I ++ ++ Sbjct: 133 ASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQMGTVIVSGSTEKVL 192 Query: 377 QDLRPEVPVSSKQMLYCT----CLSWSADGSTLYAGYTDGTIRIYKI 505 + P ++ T L + DG+ +G +DGTIR++ + Sbjct: 193 RVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRLWSL 239
>POP1_SCHPO (P87060) WD-repeat protein pop1| Length = 775 Score = 57.4 bits (137), Expect = 3e-08 Identities = 32/101 (31%), Positives = 54/101 (53%), Gaps = 2/101 (1%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 IVS S+D +++VW + L GH G V +V ++P C S G D +W+L G Sbjct: 590 IVSASYDGTLRVWKASTGVCLHVLRGHVGRVYSVTINPSRQQCISAGTDAKIRIWNLESG 649 Query: 248 KRLYSLDAGS-IINSLCFSPNRYWLCAATQD-SIKIWDLES 364 + L +L S +++ + F+ N +A D S+++WDL + Sbjct: 650 ELLQTLHGHSNLVSQVTFNQNILVSASAPPDTSLRVWDLNT 690 Score = 53.9 bits (128), Expect = 3e-07 Identities = 34/132 (25%), Positives = 62/132 (46%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG 187 RG G V V +P+ +S D +++WNL + +L TL GH VS V + + Sbjct: 614 RGHVGRVYSVTINPSR--QQCISAGTDAKIRIWNLESGELLQTLHGHSNLVSQVTFNQNI 671 Query: 188 SLCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESK 367 + AS D +WDL G L + + F + + + + ++++WD+ S Sbjct: 672 LVSASAPPDTSLRVWDLNTGSCRDILKCP--LGHIFFQHDESKVVSGSHSTLQLWDIRSG 729 Query: 368 HIVQDLRPEVPV 403 +V+DL ++ + Sbjct: 730 KLVRDLLTDLDI 741 Score = 33.5 bits (75), Expect = 0.42 Identities = 35/164 (21%), Positives = 64/164 (39%), Gaps = 16/164 (9%) Frame = +2 Query: 65 TIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTE 244 T+V+GS DR+V+VW+L + + GH + + + G T D+ + Sbjct: 458 TLVTGSTDRTVRVWDLRTGECKQVFYGHTSTIRCIKIVQ--------GNQSTTDTDDVEK 509 Query: 245 GKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLE--------SKHIVQDLRPEVP 400 R S DA S+ Y + ++ +I++W L + + D + Sbjct: 510 ENRPASNDANSM--------PPYIISSSRDCTIRLWSLPCLDDPPFVNVNENPDQNNDFT 561 Query: 401 VSSKQMLYCTCLSWSAD--------GSTLYAGYTDGTIRIYKIS 508 ++ Y L D G + + DGT+R++K S Sbjct: 562 SATTNPFYIRTLRGHTDSVREVACLGDLIVSASYDGTLRVWKAS 605
>PK1IP_BRARE (Q6TNS2) p21-activated protein kinase-interacting protein 1-like| (PAK1-interacting protein 1-like) Length = 368 Score = 57.4 bits (137), Expect = 3e-08 Identities = 41/163 (25%), Positives = 72/163 (44%) Frame = +2 Query: 20 GWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCA 199 G +SC+ F + ++SG D + VW+ + T+ H G V++++V P G L Sbjct: 88 GTISCLEFYGTSH---LLSGGQDGLICVWSTKKWECLKTIRAHKGQVTSLSVHPSGKLAL 144 Query: 200 SGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQ 379 S G D W+L EG+ + + + +SP+ D + I+ L+S I+ Sbjct: 145 SVGTDKTLRTWNLIEGRSAFIKNIKQNAEIVLWSPDGDKYAVVVNDKVDIYTLDSATIIG 204 Query: 380 DLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 + +S CL + S L G D ++RIY ++ Sbjct: 205 TIAFTKRIS--------CLKF-LKNSLLAVGGDDESVRIYDVT 238
>WDR48_MACFA (Q4R2Z6) WD-repeat protein 48| Length = 622 Score = 57.4 bits (137), Expect = 3e-08 Identities = 46/174 (26%), Positives = 76/174 (43%), Gaps = 11/174 (6%) Frame = +2 Query: 17 TGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLC 196 T WV+ + N T++S S D +VKVWN TL H YV A+A + D L Sbjct: 75 TDWVNDIVLCCNG--KTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELV 132 Query: 197 ASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCA-----------ATQDSI 343 AS G D LWD+ L + + +SL + + + A +T+ + Sbjct: 133 ASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVL 192 Query: 344 KIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 ++WD + + L+ +L + DG+ +G +DGTIR++ + Sbjct: 193 RVWDPRTCAKLMKLKGHTDNVKALLL-------NRDGTQCLSGSSDGTIRLWSL 239
>TAF73_SCHPO (O74319) Transcription initiation factor TFIID subunit taf73| (Transcription initiation factor TFIID 73 kDa subunit) (TAFII-73) Length = 642 Score = 57.4 bits (137), Expect = 3e-08 Identities = 36/121 (29%), Positives = 58/121 (47%), Gaps = 2/121 (1%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 V CV F PN A + +GS D + ++W++ + H VSA+ +S DG AS Sbjct: 490 VDCVSFHPN--AAYLATGSSDHTTRMWDVRTGGTVRVFNAHHSPVSALCMSADGLSLASA 547 Query: 206 GKDGVTLLWDLTEGKRLYS-LDAGSIINSLCFS-PNRYWLCAATQDSIKIWDLESKHIVQ 379 + G+ +WDL + S + SI+ SL FS N+ + + WDL ++ + Sbjct: 548 DESGIIKVWDLRSSNQHVSFVKHSSIVYSLSFSYDNKILVSGGADTDVNFWDLTYRNNLS 607 Query: 380 D 382 D Sbjct: 608 D 608 Score = 56.6 bits (135), Expect = 5e-08 Identities = 42/160 (26%), Positives = 75/160 (46%), Gaps = 2/160 (1%) Frame = +2 Query: 35 VRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKD 214 V+FSP F + S D++ ++W++ + GH V V+ P+ + A+G D Sbjct: 451 VQFSP--FGYYFATASHDQTARLWDVEHAAPLRVFVGHQNDVDCVSFHPNAAYLATGSSD 508 Query: 215 GVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQDS-IKIWDLESKHIVQDLR 388 T +WD+ G + +A S +++LC S + L +A + IK+WDL S + Sbjct: 509 HTTRMWDVRTGGTVRVFNAHHSPVSALCMSADGLSLASADESGIIKVWDLRSSNQHVSF- 567 Query: 389 PEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 V ++Y LS+S D L +G D + + ++ Sbjct: 568 ----VKHSSIVY--SLSFSYDNKILVSGGADTDVNFWDLT 601 Score = 41.2 bits (95), Expect = 0.002 Identities = 44/174 (25%), Positives = 74/174 (42%), Gaps = 14/174 (8%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCK------------LRCTLDGHGGYVSAV 169 V+C FS + A G D S+ +++ TN + +L GH V V Sbjct: 352 VNCAAFSDD--ASMFALGCADSSIHLYSSTNNGPQPLVGSQNEPLQKSSLIGHTRPVFGV 409 Query: 170 AVSPDGSLCASGGKDGVTLLWDL-TEGKRLYSLDAGSIINSLCFSPNRYWLCAATQD-SI 343 ++SP S +DG T LW T+ + + I + FSP Y+ A+ D + Sbjct: 410 SISPQKEFILSCSEDGFTRLWSKDTKSTIVKYAGHNAPIWDVQFSPFGYYFATASHDQTA 469 Query: 344 KIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 ++WD+E LR V + C+S+ + + L G +D T R++ + Sbjct: 470 RLWDVEH---AAPLRVFVGHQND----VDCVSFHPNAAYLATGSSDHTTRMWDV 516
>WDR48_PONPY (Q5RAW8) WD-repeat protein 48| Length = 677 Score = 57.4 bits (137), Expect = 3e-08 Identities = 46/174 (26%), Positives = 76/174 (43%), Gaps = 11/174 (6%) Frame = +2 Query: 17 TGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLC 196 T WV+ + N T++S S D +VKVWN TL H YV A+A + D L Sbjct: 75 TDWVNDIVLCCNG--KTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELV 132 Query: 197 ASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCA-----------ATQDSI 343 AS G D LWD+ L + + +SL + + + A +T+ + Sbjct: 133 ASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVL 192 Query: 344 KIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 ++WD + + L+ +L + DG+ +G +DGTIR++ + Sbjct: 193 RVWDPRTCAKLMKLKGHTDNVKALLL-------NRDGTQCLSGSSDGTIRLWSL 239
>WDR48_HUMAN (Q8TAF3) WD-repeat protein 48 (WD repeat endosomal protein) (p80)| Length = 677 Score = 57.4 bits (137), Expect = 3e-08 Identities = 46/174 (26%), Positives = 76/174 (43%), Gaps = 11/174 (6%) Frame = +2 Query: 17 TGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLC 196 T WV+ + N T++S S D +VKVWN TL H YV A+A + D L Sbjct: 75 TDWVNDIVLCCNG--KTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELV 132 Query: 197 ASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCA-----------ATQDSI 343 AS G D LWD+ L + + +SL + + + A +T+ + Sbjct: 133 ASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVL 192 Query: 344 KIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 ++WD + + L+ +L + DG+ +G +DGTIR++ + Sbjct: 193 RVWDPRTCAKLMKLKGHTDNVKALLL-------NRDGTQCLSGSSDGTIRLWSL 239
>PRP4_YEAST (P20053) U4/U6 small nuclear ribonucleoprotein PRP4| Length = 465 Score = 57.4 bits (137), Expect = 3e-08 Identities = 34/116 (29%), Positives = 62/116 (53%), Gaps = 2/116 (1%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 +S V++ P+ I S S D + ++W+ + + +GH V +++ DGSL SG Sbjct: 268 ISDVKYHPSG--KFIGSASHDMTWRLWDASTHQELLLQEGHDKGVFSLSFQCDGSLVCSG 325 Query: 206 GKDGVTLLWDLTEGKRLYSLDAGS-IINSLCFSPNRYWLCAATQDS-IKIWDLESK 367 G D +++LWD+ G ++ +L S I ++ +SPN Y + D I +WD+ + Sbjct: 326 GMDSLSMLWDIRSGSKVMTLAGHSKPIYTVAWSPNGYQVATGGGDGIINVWDIRKR 381 Score = 40.4 bits (93), Expect = 0.003 Identities = 38/152 (25%), Positives = 64/152 (42%), Gaps = 6/152 (3%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTN----CKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWD 235 ++S + D +K + +N +L L GH +S V P G S D LWD Sbjct: 234 MISCAEDGLIKNFQYSNEEGGLRLLGDLVGHERRISDVKYHPSGKFIGSASHDMTWRLWD 293 Query: 236 LTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQDSIK-IWDLESKHIVQDLRPEVPVSS 409 + + L + + SL F + +C+ DS+ +WD+ S V L Sbjct: 294 ASTHQELLLQEGHDKGVFSLSFQCDGSLVCSGGMDSLSMLWDIRSGSKVMTL-----AGH 348 Query: 410 KQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 + +Y ++WS +G + G DG I ++ I Sbjct: 349 SKPIY--TVAWSPNGYQVATGGGDGIINVWDI 378 Score = 32.0 bits (71), Expect = 1.2 Identities = 19/70 (27%), Positives = 33/70 (47%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 V+ VRFS + +VS +D + V++ +L GH + ++ +S + SG Sbjct: 396 VTQVRFSKEDGGKKLVSCGYDNLINVYSSDTWLKMGSLAGHTDKIISLDISNNSHFLVSG 455 Query: 206 GKDGVTLLWD 235 G D LW+ Sbjct: 456 GWDRSIKLWN 465
>WSB1_HUMAN (Q9Y6I7) WD repeat and SOCS box-containing protein 1 (WSB-1) (SOCS| box-containing WD protein SWiP-1) Length = 421 Score = 57.0 bits (136), Expect = 4e-08 Identities = 49/176 (27%), Positives = 77/176 (43%), Gaps = 15/176 (8%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG 187 RG WV FSP++ V S ++V +WN+ + L+GH V A SPDG Sbjct: 211 RGHQNWVYSCAFSPDSSMLCSVGAS--KAVFLWNMDKYTMIRKLEGHHHDVVACDFSPDG 268 Query: 188 SLCASGGKDGVTLLWDLTEGKRLYS----------LDAGSI----INSLCFSPNRYWLCA 325 +L A+ D +WD G L + AG + S+ FS + + + Sbjct: 269 ALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVSFSHDGLHVAS 328 Query: 326 ATQDS-IKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTI 490 D ++ W ++ + VQ P+S+ C ++S DGS L AG DG++ Sbjct: 329 LADDKMVRFWRIDEDYPVQ----VAPLSNG-----LCCAFSTDGSVLAAGTHDGSV 375 Score = 51.2 bits (121), Expect = 2e-06 Identities = 44/163 (26%), Positives = 76/163 (46%), Gaps = 13/163 (7%) Frame = +2 Query: 56 FAPT----IVSGSWDRSVKVWNLTNC-KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGV 220 FAP +VS S D++++VW+L + + L GH +V + A SPD S+ S G Sbjct: 178 FAPDGSLILVSASRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKA 237 Query: 221 TLLWDLTEGKRLYSLDAGSIINSLC-FSPNRYWLCAATQDS-IKIWDLESKHIVQD---- 382 LW++ + + L+ C FSP+ L A+ D+ + IWD + I+ + Sbjct: 238 VFLWNMDKYTMIRKLEGHHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILMEFGHL 297 Query: 383 LRPEVPV--SSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 P P+ + +S+S DG + + D +R ++I Sbjct: 298 FPPPTPIFAGGANDRWVRSVSFSHDGLHVASLADDKMVRFWRI 340 Score = 43.9 bits (102), Expect = 3e-04 Identities = 27/110 (24%), Positives = 54/110 (49%), Gaps = 4/110 (3%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSL-CASGGKDGVTLLWDLTE 244 + +G + +K+W++ KL L H V + +PDGSL S +D +WDL + Sbjct: 143 LATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKD 202 Query: 245 GKRLYSLDAG--SIINSLCFSPNRYWLCA-ATQDSIKIWDLESKHIVQDL 385 + + G + + S FSP+ LC+ ++ +W+++ +++ L Sbjct: 203 DGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKL 252
>GBB2_TOBAC (P93398) Guanine nucleotide-binding protein beta subunit 2| Length = 377 Score = 57.0 bits (136), Expect = 4e-08 Identities = 51/175 (29%), Positives = 75/175 (42%), Gaps = 8/175 (4%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNL-TNCKLRCTLDGHGGYVSAVAVSPDG 187 G T V V S +N VSGS D + ++W+ + + T GH G V+ V PDG Sbjct: 202 GHTADVQSVSISSSN-PRLFVSGSCDSTARLWDTRVASRAQRTFYGHEGDVNTVKFFPDG 260 Query: 188 SLCASGGKDGVTLLWDLTEGKRL--YSLDAGS----IINSLCFS-PNRYWLCAATQDSIK 346 + +G DG L+D+ G +L Y G + S+ FS R + Sbjct: 261 NRFGTGSDDGTCRLFDIRTGHQLQVYYQPHGDGDIPHVTSMAFSISGRLLFVGYSNGDCY 320 Query: 347 IWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISG 511 +WD +V +L V + +CL SADGS L G D ++I+ G Sbjct: 321 VWDTLLAKVVLNLG---AVQNSHEGRISCLGLSADGSALCTGSWDTNLKIWAFGG 372 Score = 46.2 bits (108), Expect = 6e-05 Identities = 46/189 (24%), Positives = 75/189 (39%), Gaps = 25/189 (13%) Frame = +2 Query: 14 PTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLT-------NCKLRCTLDGHGGYVSAVA 172 P WV FSP+ ++ G D ++NL N + L GH GYVS+ Sbjct: 106 PCAWVMTCAFSPSG--QSVACGGLDSVCSIFNLNSPIDKDGNHPVSRMLSGHKGYVSSCQ 163 Query: 173 VSPDGS---LCASGGKDGVTLLWDLTEGKRL----------YSLDAGSIINSLCFSPNRY 313 PD + +SG D +LWD+T G R ++ D S+ S+ S R Sbjct: 164 YVPDEDTHVITSSG--DQTCVLWDITTGLRTSVFGGEFQSGHTADVQSV--SISSSNPRL 219 Query: 314 WLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLY-----CTCLSWSADGSTLYAGYT 478 ++ + + ++WD V +++ Y + + DG+ G Sbjct: 220 FVSGSCDSTARLWD-----------TRVASRAQRTFYGHEGDVNTVKFFPDGNRFGTGSD 268 Query: 479 DGTIRIYKI 505 DGT R++ I Sbjct: 269 DGTCRLFDI 277 Score = 29.6 bits (65), Expect = 6.1 Identities = 20/88 (22%), Positives = 45/88 (51%), Gaps = 2/88 (2%) Frame = +2 Query: 107 NLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLDAG-SII 283 +L C++ L GH G V ++ +P+ + S +DG ++W+ ++ +++ + + Sbjct: 54 DLVCCRI---LQGHTGKVYSLDWTPEKNRIVSASQDGRLIVWNALTSQKTHAIKLPCAWV 110 Query: 284 NSLCFSPNRYWLCAATQDSI-KIWDLES 364 + FSP+ + DS+ I++L S Sbjct: 111 MTCAFSPSGQSVACGGLDSVCSIFNLNS 138
>TLE1_XENLA (O42469) Enhancer of split groucho-like protein 1| Length = 767 Score = 56.6 bits (135), Expect = 5e-08 Identities = 35/122 (28%), Positives = 57/122 (46%), Gaps = 3/122 (2%) Frame = +2 Query: 86 DRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSL 265 D ++ VW+L N L GH S + +S DG+ +GG D WDL EG++L Sbjct: 592 DGNIVVWDLQNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRCWDLREGRQLQQH 651 Query: 266 DAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQML---YCTCL 436 D S I SL + P WL + S ++E H+ + + ++ + +L + +C Sbjct: 652 DFNSQIFSLGYCPTGEWLAVGMESS----NIEVLHVSKPDKYQLHLHESCVLSLQFASCG 707 Query: 437 SW 442 W Sbjct: 708 KW 709 Score = 43.9 bits (102), Expect = 3e-04 Identities = 34/148 (22%), Positives = 63/148 (42%), Gaps = 11/148 (7%) Frame = +2 Query: 95 VKVWNLTN-------CKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL---TE 244 VKVW++ +L C Y+ + + PDG GG+ +WDL T Sbjct: 504 VKVWDVGQPGTKTPVAQLDCL--NRDNYIRSCKLLPDGRSLIVGGEASTLSIWDLASPTP 561 Query: 245 GKRLYSLDAGSIINSLCFSPN-RYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQML 421 + + +L SP+ + + +I +WDL+++ +V+ + +S Sbjct: 562 RIKAELTSSAPACYALAISPDAKVCFSCCSDGNIVVWDLQNQTLVRQFQGHTDGAS---- 617 Query: 422 YCTCLSWSADGSTLYAGYTDGTIRIYKI 505 C+ S DG+ L+ G D T+R + + Sbjct: 618 ---CIDISHDGTKLWTGGLDNTVRCWDL 642 Score = 37.7 bits (86), Expect = 0.022 Identities = 29/135 (21%), Positives = 57/135 (42%), Gaps = 5/135 (3%) Frame = +2 Query: 65 TIVSGSWDRSVKVWNLTNC--KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL 238 +++ G ++ +W+L + +++ L A+A+SPD +C S DG ++WDL Sbjct: 541 SLIVGGEASTLSIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIVVWDL 600 Query: 239 ---TEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSS 409 T ++ G+ + + W ++++ WDL +Q + S Sbjct: 601 QNQTLVRQFQGHTDGASCIDISHDGTKLW-TGGLDNTVRCWDLREGRQLQQHDFNSQIFS 659 Query: 410 KQMLYCTCLSWSADG 454 + YC W A G Sbjct: 660 --LGYCPTGEWLAVG 672
>FAN_HUMAN (Q92636) Protein FAN (Factor associated with N-SMase activation)| (Factor associated with neutral sphingomyelinase activation) Length = 917 Score = 56.6 bits (135), Expect = 5e-08 Identities = 39/163 (23%), Positives = 74/163 (45%), Gaps = 11/163 (6%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGY---------VSAVAVSPDGSLCASGGKDGV 220 + S SWD +VKVW+ ++ T H V ++++ +L SG K+G Sbjct: 727 LYSASWDSTVKVWSGVPAEMPGTKRHHFDLLAELEHDVSVDTISLNAASTLLVSGTKEGT 786 Query: 221 TLLWDLTEGKRLYSLDAGS-IINSLCFSP-NRYWLCAATQDSIKIWDLESKHIVQDLRPE 394 +WDLT ++ + S I+ FSP +R+ L T + + D+++ ++ + + Sbjct: 787 VNIWDLTTATLMHQIPCHSGIVCDTAFSPDSRHVLSTGTDGCLNVIDVQTGMLISSMTSD 846 Query: 395 VPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISGFSYS 523 P TC W DG+++ +G G + ++ + G S Sbjct: 847 EPQ--------TCFVW--DGNSVLSGSQSGELLVWDLLGAKIS 879 Score = 48.1 bits (113), Expect = 2e-05 Identities = 39/160 (24%), Positives = 65/160 (40%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 VS S N + +VSG+ + +V +W+LT L + H G V A SPD S Sbjct: 764 VSVDTISLNAASTLLVSGTKEGTVNIWDLTTATLMHQIPCHSGIVCDTAFSPDSRHVLST 823 Query: 206 GKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDL 385 G DG + D+ G + S+ + + N L + + +WDL I + + Sbjct: 824 GTDGCLNVIDVQTGMLISSMTSDEPQTCFVWDGNSV-LSGSQSGELLVWDLLGAKISERI 882 Query: 386 RPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 + TC+ + S++ G D I +K+ Sbjct: 883 QGHTGA-------VTCIWMNEQCSSIITGGEDRQIIFWKL 915
>IF32_YEAST (P40217) Eukaryotic translation initiation factor 3 39 kDa subunit| (eIF3 p39) (Translation initiation factor eIF3, p39 subunit) Length = 347 Score = 56.6 bits (135), Expect = 5e-08 Identities = 45/165 (27%), Positives = 71/165 (43%), Gaps = 12/165 (7%) Frame = +2 Query: 50 NNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLL 229 N + S S D S VW N + TLDGH G + ++ V C +G D L Sbjct: 19 NKEGDLLFSCSKDSSASVWYSLNGERLGTLDGHTGTIWSIDVDCFTKYCVTGSADYSIKL 78 Query: 230 WDLTEGKRLYSLDAGSIINSLCFSP-NRYWLC-----AATQDSIKIWDLESKHIVQDLR- 388 WD++ G+ + + + + + FSP Y+L SI I+++E +L Sbjct: 79 WDVSNGQCVATWKSPVPVKRVEFSPCGNYFLAILDNVMKNPGSINIYEIERDSATHELTK 138 Query: 389 -PEVP----VSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 E P ++ + + T WS G + AG+ DG I Y +S Sbjct: 139 VSEEPIHKIITHEGLDAATVAGWSTKGKYIIAGHKDGKISKYDVS 183 Score = 43.5 bits (101), Expect = 4e-04 Identities = 31/101 (30%), Positives = 49/101 (48%), Gaps = 4/101 (3%) Frame = +2 Query: 137 LDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLD--AGSI--INSLCFSP 304 L GH ++ V + +G L S KD +W G+RL +LD G+I I+ CF+ Sbjct: 6 LTGHERPLTQVKYNKEGDLLFSCSKDSSASVWYSLNGERLGTLDGHTGTIWSIDVDCFT- 64 Query: 305 NRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYC 427 +Y + + SIK+WD+ + V + VPV + C Sbjct: 65 -KYCVTGSADYSIKLWDVSNGQCVATWKSPVPVKRVEFSPC 104 Score = 33.5 bits (75), Expect = 0.42 Identities = 14/27 (51%), Positives = 20/27 (74%) Frame = +2 Query: 137 LDGHGGYVSAVAVSPDGSLCASGGKDG 217 + GH G ++ VA+SP G+ ASGG+DG Sbjct: 289 VQGHFGPLNTVAISPQGTSYASGGEDG 315
>FBXW7_DROME (Q9VZF4) F-box/WD-repeat protein 7 (F-box and WD-40 domain protein 7)| (Protein archipelago) Length = 1326 Score = 56.6 bits (135), Expect = 5e-08 Identities = 43/159 (27%), Positives = 78/159 (49%), Gaps = 1/159 (0%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 ++C++FS N IVSGS D ++KVW+ N K TL GH G V + +S G++ SG Sbjct: 998 ITCLQFSGNR----IVSGSDDNTLKVWSAVNGKCLRTLVGHTGGVWSSQMS--GNIIISG 1051 Query: 206 GKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQD 382 D +WD+ G +++L G C + + + ++D ++++WD+E + Sbjct: 1052 STDRTLKVWDMDSGACVHTLQ-GHTSTVRCMHLHGSKVVSGSRDATLRVWDIEQGSCLH- 1109 Query: 383 LRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 V + C+ + DG + +G D ++I+ Sbjct: 1110 ------VLVGHLAAVRCVQY--DGKLIVSGAYDYMVKIW 1140 Score = 54.3 bits (129), Expect = 2e-07 Identities = 30/110 (27%), Positives = 60/110 (54%), Gaps = 4/110 (3%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 +VSGS D S++VW++ + TL GH S + + ++ SG D +WD+T G Sbjct: 1168 VVSGSLDTSIRVWDVETGNCKHTLMGHQSLTSGMELRQ--NILVSGNADSTVKVWDITTG 1225 Query: 248 KRLYSLDA----GSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDL 385 + L +L S + L F+ +R+ + ++ ++K+WD+++ +++L Sbjct: 1226 QCLQTLSGPNKHHSAVTCLQFN-SRFVVTSSDDGTVKLWDVKTGDFIRNL 1274 Score = 48.5 bits (114), Expect = 1e-05 Identities = 38/160 (23%), Positives = 69/160 (43%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 V CV++ IVSG++D VK+W+ + TL GH V ++ DG SG Sbjct: 1118 VRCVQYD----GKLIVSGAYDYMVKIWHPERQECLHTLQGHTNRVYSLQF--DGLHVVSG 1171 Query: 206 GKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDL 385 D +WD+ G ++L + S + ++K+WD+ + +Q L Sbjct: 1172 SLDTSIRVWDVETGNCKHTLMGHQSLTSGMELRQNILVSGNADSTVKVWDITTGQCLQTL 1231 Query: 386 RPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 +K TCL +++ + DGT++++ + Sbjct: 1232 SG----PNKHHSAVTCLQFNS--RFVVTSSDDGTVKLWDV 1265 Score = 45.1 bits (105), Expect = 1e-04 Identities = 41/168 (24%), Positives = 74/168 (44%), Gaps = 1/168 (0%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG 187 +G T V C+ + +VSGS D +++VW++ L GH V V DG Sbjct: 1072 QGHTSTVRCMHLHGSK----VVSGSRDATLRVWDIEQGSCLHVLVGHLAAVRCVQY--DG 1125 Query: 188 SLCASGGKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQDSIKIWDLES 364 L SG D + +W + L++L + + SL F + + + SI++WD+E+ Sbjct: 1126 KLIVSGAYDYMVKIWHPERQECLHTLQGHTNRVYSLQFD-GLHVVSGSLDTSIRVWDVET 1184 Query: 365 KHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 + L ++S L + L +G D T++++ I+ Sbjct: 1185 GNCKHTLMGHQSLTSGMEL---------RQNILVSGNADSTVKVWDIT 1223 Score = 41.2 bits (95), Expect = 0.002 Identities = 25/73 (34%), Positives = 39/73 (53%), Gaps = 4/73 (5%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAV-AVSPDGSLCASGGKDGVTLLWDLTE 244 +VSG+ D +VKVW++T + TL G + SAV + + + DG LWD+ Sbjct: 1208 LVSGNADSTVKVWDITTGQCLQTLSGPNKHHSAVTCLQFNSRFVVTSSDDGTVKLWDVKT 1267 Query: 245 G---KRLYSLDAG 274 G + L +LD+G Sbjct: 1268 GDFIRNLVALDSG 1280
>AAMP_CANFA (Q7YR70) Angio-associated migratory cell protein| Length = 435 Score = 56.2 bits (134), Expect = 6e-08 Identities = 43/161 (26%), Positives = 68/161 (42%), Gaps = 1/161 (0%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 V CV P + G D++ VW L++ +L GH V+ S D +L A+G Sbjct: 95 VFCVSLDPKTNTLAVTGGEDDKAF-VWRLSDGELLFECAGHKDSVTCAGFSHDSTLVATG 153 Query: 206 GKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQD 382 G+ +W + + ++S +AG + + + P L A T D + +W + + Sbjct: 154 DMSGLLKVWQVDTKEEVWSFEAGD-LEWMEWHPRAPVLLAGTADGNTWMWKVPNGDCKTF 212 Query: 383 LRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 P P TC DG GY DGTIRI+ + Sbjct: 213 QGPNCP--------ATCGRVLPDGKRAVVGYEDGTIRIWDL 245 Score = 43.9 bits (102), Expect = 3e-04 Identities = 41/171 (23%), Positives = 69/171 (40%), Gaps = 21/171 (12%) Frame = +2 Query: 59 APTIVSGSWDRSVKVWNLTN--CKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLW 232 AP +++G+ D + +W + N CK T G + V PDG G +DG +W Sbjct: 187 APVLLAGTADGNTWMWKVPNGDCK---TFQGPNCPATCGRVLPDGKRAVVGYEDGTIRIW 243 Query: 233 DLTEGKRLYSLDA--GSIINSLCFSPNR---YWLCAATQDSIKIWDLESKHIVQDLRPEV 397 DL +G ++ L G C + N+ L + ++ + +V RPE Sbjct: 244 DLKQGSPIHVLKGTEGHQGPLTCVATNQDGSLILTGSVDCQAQLVSATTGKVVGVFRPET 303 Query: 398 PVSS--------------KQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 S + + +C+ + +A GY DGT+ IY +S Sbjct: 304 VASQPNVGEGEESESNSVESLGFCSVMPLAA------VGYLDGTLAIYDLS 348
>AAMP_PONPY (Q5RCG7) Angio-associated migratory cell protein| Length = 434 Score = 56.2 bits (134), Expect = 6e-08 Identities = 43/161 (26%), Positives = 68/161 (42%), Gaps = 1/161 (0%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 V CV P + G D++ VW L++ +L GH V+ S D +L A+G Sbjct: 94 VFCVSLDPKTNTLAVTGGEDDKAF-VWRLSDGELLFECAGHKDSVTCAGFSHDSTLVATG 152 Query: 206 GKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQD 382 G+ +W + + ++S +AG + + + P L A T D + +W + + Sbjct: 153 DMSGLLKVWQVDTKEEVWSFEAGD-LEWMEWHPRAPVLLAGTADGNTWMWKVPNGDCKTF 211 Query: 383 LRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 P P TC DG GY DGTIRI+ + Sbjct: 212 QGPNCP--------ATCGRVLPDGKRAVVGYEDGTIRIWDL 244 Score = 44.3 bits (103), Expect = 2e-04 Identities = 41/171 (23%), Positives = 69/171 (40%), Gaps = 21/171 (12%) Frame = +2 Query: 59 APTIVSGSWDRSVKVWNLTN--CKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLW 232 AP +++G+ D + +W + N CK T G + V PDG G +DG +W Sbjct: 186 APVLLAGTADGNTWMWKVPNGDCK---TFQGPNCPATCGRVLPDGKRAVVGYEDGTIRIW 242 Query: 233 DLTEGKRLYSLDA--GSIINSLCFSPNR---YWLCAATQDSIKIWDLESKHIVQDLRPEV 397 DL +G ++ L G C + N+ L + K+ + +V RPE Sbjct: 243 DLKQGSPIHVLKGTEGHQGPLTCVATNQDGSLILTGSVDCQAKLVSATTGKVVGVFRPET 302 Query: 398 PVSS--------------KQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 S + + +C+ + +A GY DGT+ IY ++ Sbjct: 303 VASQPSLGEGEESESNSVESLGFCSVMPLAA------VGYLDGTLAIYDLA 347
>AAMP_HUMAN (Q13685) Angio-associated migratory cell protein| Length = 434 Score = 56.2 bits (134), Expect = 6e-08 Identities = 43/161 (26%), Positives = 68/161 (42%), Gaps = 1/161 (0%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 V CV P + G D++ VW L++ +L GH V+ S D +L A+G Sbjct: 94 VFCVSLDPKTNTLAVTGGEDDKAF-VWRLSDGELLFECAGHKDSVTCAGFSHDSTLVATG 152 Query: 206 GKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQD 382 G+ +W + + ++S +AG + + + P L A T D + +W + + Sbjct: 153 DMSGLLKVWQVDTKEEVWSFEAGD-LEWMEWHPRAPVLLAGTADGNTWMWKVPNGDCKTF 211 Query: 383 LRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 P P TC DG GY DGTIRI+ + Sbjct: 212 QGPNCP--------ATCGRVLPDGKRAVVGYEDGTIRIWDL 244 Score = 44.3 bits (103), Expect = 2e-04 Identities = 41/171 (23%), Positives = 69/171 (40%), Gaps = 21/171 (12%) Frame = +2 Query: 59 APTIVSGSWDRSVKVWNLTN--CKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLW 232 AP +++G+ D + +W + N CK T G + V PDG G +DG +W Sbjct: 186 APVLLAGTADGNTWMWKVPNGDCK---TFQGPNCPATCGRVLPDGKRAVVGYEDGTIRIW 242 Query: 233 DLTEGKRLYSLDA--GSIINSLCFSPNR---YWLCAATQDSIKIWDLESKHIVQDLRPEV 397 DL +G ++ L G C + N+ L + K+ + +V RPE Sbjct: 243 DLKQGSPIHVLKGTEGHQGPLTCVAANQDGSLILTGSVDCQAKLVSATTGKVVGVFRPET 302 Query: 398 PVSS--------------KQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 S + + +C+ + +A GY DGT+ IY ++ Sbjct: 303 VASQPSLGEGEESESNSVESLGFCSVMPLAA------VGYLDGTLAIYDLA 347
>GBB_ORYSA (Q40687) Guanine nucleotide-binding protein beta subunit| Length = 380 Score = 56.2 bits (134), Expect = 6e-08 Identities = 44/157 (28%), Positives = 70/157 (44%), Gaps = 10/157 (6%) Frame = +2 Query: 71 VSGSWDRSVKVWNLTNCKLRC-TLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 VSGS D +V++W++ T GH G +++V PDG +G DG L+D+ G Sbjct: 222 VSGSCDATVRLWDIRIASRAVRTYHGHEGDINSVKFFPDGQRFGTGSDDGTCRLFDVRTG 281 Query: 248 KRL--YSLDAG------SIINSLCFS-PNRYWLCAATQDSIKIWDLESKHIVQDLRPEVP 400 +L YS + + S+ FS R + +WD +V +L Sbjct: 282 HQLQVYSREPDRNDNELPTVTSIAFSISGRLLFAGYSNGDCYVWDTLLAEVVLNLG---N 338 Query: 401 VSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISG 511 + + +CL S+DGS L G D ++I+ SG Sbjct: 339 LQNSHEGRISCLGLSSDGSALCTGSWDKNLKIWAFSG 375 Score = 35.4 bits (80), Expect = 0.11 Identities = 36/176 (20%), Positives = 77/176 (43%), Gaps = 10/176 (5%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG 187 +G +G V + ++P IVS S D + VWN + + H +V A +P+G Sbjct: 63 QGHSGKVYSLDWTPEK--NWIVSASQDGRLIVWNALTSQKTHAIKLHCPWVMTCAFAPNG 120 Query: 188 SLCASGGKDGVTLLWDL-TEGKRLYSLDAGSI-------INSLCFSPNR--YWLCAATQD 337 A GG D +++L ++ R ++ I ++S + P++ + ++ Sbjct: 121 QSVACGGLDSACSIFNLNSQADRDGNIPVSRILTGHKGYVSSCQYVPDQETRLITSSGDQ 180 Query: 338 SIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 + +WD+ + + E P + ++ S++ + +G D T+R++ I Sbjct: 181 TCVLWDVTTGQRISIFGGEFPSGHTADVLSLSIN-SSNSNMFVSGSCDATVRLWDI 235 Score = 33.1 bits (74), Expect = 0.55 Identities = 22/93 (23%), Positives = 45/93 (48%), Gaps = 2/93 (2%) Frame = +2 Query: 134 TLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLDAG-SIINSLCFSPN- 307 TL GH G V ++ +P+ + S +DG ++W+ ++ +++ + + F+PN Sbjct: 61 TLQGHSGKVYSLDWTPEKNWIVSASQDGRLIVWNALTSQKTHAIKLHCPWVMTCAFAPNG 120 Query: 308 RYWLCAATQDSIKIWDLESKHIVQDLRPEVPVS 406 + C + I++L S+ D +PVS Sbjct: 121 QSVACGGLDSACSIFNLNSQ---ADRDGNIPVS 150
>WDR31_MOUSE (Q9JHB4) WD-repeat protein 31 (Spermatid WD-repeat protein) (spWD)| Length = 367 Score = 56.2 bits (134), Expect = 6e-08 Identities = 31/97 (31%), Positives = 54/97 (55%), Gaps = 3/97 (3%) Frame = +2 Query: 74 SGSWDRSVKVWNLTNCKL-RCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGK 250 S S D++V +W+L R L GH V+ +AVSPD S +G +D LLWD+ G+ Sbjct: 120 SASRDKTVLMWDLQGSSHPRQQLSGHAMVVTGLAVSPDSSQLCTGSRDNSLLLWDVGTGQ 179 Query: 251 RLYSLDAG-SIINSLCFSPNRYWLCAATQD-SIKIWD 355 + +++ LC+ P+ ++ ++D +I++WD Sbjct: 180 CVERASVSRNLVTHLCWVPSEPYIVQTSEDKTIRLWD 216 Score = 43.9 bits (102), Expect = 3e-04 Identities = 34/150 (22%), Positives = 61/150 (40%), Gaps = 3/150 (2%) Frame = +2 Query: 71 VSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL--TE 244 +SG D++ +N ++ GH ++ +A P + S +D L+WDL + Sbjct: 77 ISGGKDKTAVAYNWKTGRMVKRFTGHEREITKIACIPKANQFFSASRDKTVLMWDLQGSS 136 Query: 245 GKRLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQDLRPEVPVSSKQML 421 R ++ L SP+ LC ++D S+ +WD+ + V+ +S Sbjct: 137 HPRQQLSGHAMVVTGLAVSPDSSQLCTGSRDNSLLLWDVGTGQCVER-------ASVSRN 189 Query: 422 YCTCLSWSADGSTLYAGYTDGTIRIYKISG 511 T L W + D TIR++ G Sbjct: 190 LVTHLCWVPSEPYIVQTSEDKTIRLWDSRG 219 Score = 37.0 bits (84), Expect = 0.038 Identities = 31/123 (25%), Positives = 53/123 (43%), Gaps = 3/123 (2%) Frame = +2 Query: 146 HGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGK--RLYSLDAGSIINSLCFSPNRYWL 319 H VS +A + LC SGGKD + ++ G+ + ++ I C + Sbjct: 61 HVDTVSVIATL-NSDLCISGGKDKTAVAYNWKTGRMVKRFTGHEREITKIACIPKANQFF 119 Query: 320 CAATQDSIKIWDLE-SKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRI 496 A+ ++ +WDL+ S H Q L S + T L+ S D S L G D ++ + Sbjct: 120 SASRDKTVLMWDLQGSSHPRQQL-------SGHAMVVTGLAVSPDSSQLCTGSRDNSLLL 172 Query: 497 YKI 505 + + Sbjct: 173 WDV 175 Score = 33.5 bits (75), Expect = 0.42 Identities = 28/85 (32%), Positives = 37/85 (43%), Gaps = 4/85 (4%) Frame = +2 Query: 29 SCVRFSPNNFA--PTIVSGSWDRSVKVWNLTN--CKLRCTLDGHGGYVSAVAVSPDGSLC 196 SCV F P + A P I + + D VK+WN C +LDG G S LC Sbjct: 283 SCV-FLPKSTALMPMIATSAHDSKVKIWNQDTGACLSTLSLDGSGPLTSLAVGDISSLLC 341 Query: 197 ASGGKDGVTLLWDLTEGKRLYSLDA 271 AS + L D ++G L + A Sbjct: 342 ASFYRGVHLLRVDHSQGLELQEVAA 366
>SCONB_EMENI (Q00659) Sulfur metabolite repression control protein| Length = 678 Score = 55.8 bits (133), Expect = 8e-08 Identities = 37/132 (28%), Positives = 67/132 (50%), Gaps = 2/132 (1%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG 187 RG + C++F ++SGS DR++KVWN + T GH G V + + D Sbjct: 386 RGHESGIRCLQFDDTK----LISGSMDRTIKVWNWRTGECISTYTGHRGGV--IGLHFDA 439 Query: 188 SLCASGGKDGVTLLWDLTEGKRLYSLDAGS-IINSLCFSPNRYWLCAATQD-SIKIWDLE 361 S+ ASG D +W+ E K +SL + +N++ + + +A+ D ++++WDL+ Sbjct: 440 SILASGSVDKTVKIWNF-EDKSTFSLRGHTDWVNAVRVDTSSRTVFSASDDCTVRLWDLD 498 Query: 362 SKHIVQDLRPEV 397 +K ++ V Sbjct: 499 TKTCIRTFHGHV 510 Score = 41.6 bits (96), Expect = 0.002 Identities = 32/122 (26%), Positives = 56/122 (45%), Gaps = 2/122 (1%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG 187 +G T V C++F N A +GS+D ++K+W+ + TL GH + + D Sbjct: 346 KGHTNGVMCLQFEDNILA----TGSYDTTIKIWDTETGEELRTLRGHESGIRCLQF--DD 399 Query: 188 SLCASGGKDGVTLLWDLTEGKRL--YSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLE 361 + SG D +W+ G+ + Y+ G +I L F + + ++KIW+ E Sbjct: 400 TKLISGSMDRTIKVWNWRTGECISTYTGHRGGVI-GLHFDAS-ILASGSVDKTVKIWNFE 457 Query: 362 SK 367 K Sbjct: 458 DK 459 Score = 38.5 bits (88), Expect = 0.013 Identities = 35/135 (25%), Positives = 58/135 (42%), Gaps = 17/135 (12%) Frame = +2 Query: 2 SARGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSP 181 S RG T WV+ VR ++ T+ S S D +V++W+L T GH G V V P Sbjct: 463 SLRGHTDWVNAVRVDTSS--RTVFSASDDCTVRLWDLDTKTCIRTFHGHVGQVQQVVPLP 520 Query: 182 --------------DGSLCASGGKDGVTLLWDL-TEGKRLYSLDA--GSIINSLCFSPNR 310 D SG + ++ + E YS + G+ ++ +P R Sbjct: 521 REFEFEEHDAECENDDLSTTSGDANPPSIQASMGLEPNAAYSQSSAFGTSFDNGRAAPPR 580 Query: 311 YWLCAATQDSIKIWD 355 Y + +A +I++W+ Sbjct: 581 YMVTSALDSTIRLWE 595 Score = 34.3 bits (77), Expect = 0.25 Identities = 18/49 (36%), Positives = 27/49 (55%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKD 214 IVSG+ DR +K+W+ K T GH G V+ + + S A+G +D Sbjct: 622 IVSGAEDRMIKIWDPRTGKCERTFTGHSGPVTCIGLG--DSRFATGSED 668
>COPB2_MOUSE (O55029) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| (p102) Length = 905 Score = 55.8 bits (133), Expect = 8e-08 Identities = 45/179 (25%), Positives = 76/179 (42%), Gaps = 7/179 (3%) Frame = +2 Query: 23 WVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCT--LDGHGGYVSAVAVSP-DGSL 193 ++ C+ P P I++ S D +K+W+ K C+ +GH YV + ++P D + Sbjct: 101 YIRCIAVHPTQ--PFILTSSDDMLIKLWDWDK-KWSCSQVFEGHTHYVMQIVINPKDNNQ 157 Query: 194 CASGGKDGVTLLWDLTEGKRLYSLDAG----SIINSLCFSPNRYWLCAATQDSIKIWDLE 361 AS D +W L ++L+ + I+ Y + A +KIWD + Sbjct: 158 FASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQ 217 Query: 362 SKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISGFSYSS*IMY 538 +K VQ L S C S+ + + G DGT+RI+ S + S + Y Sbjct: 218 NKTCVQTLEGHAQNVS-------CASFHPELPIIITGSEDGTVRIWHSSTYRLESTLNY 269 Score = 51.6 bits (122), Expect = 1e-06 Identities = 37/153 (24%), Positives = 68/153 (44%), Gaps = 1/153 (0%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 V+C+ + P ++SG+ DR VK+W+ N TL+GH VS + P+ + +G Sbjct: 188 VNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITG 247 Query: 206 GKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKI-WDLESKHIVQD 382 +DG +W Y L+ ++L + R W A+ + S + + I+ Sbjct: 248 SEDGTVRIWH----SSTYRLE-----STLNYGMERVWCVASLRGSNNVALGYDEGSIIVK 298 Query: 383 LRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTD 481 L E P +S A+G ++A +++ Sbjct: 299 LGREEP----------AMSMDANGKIIWAKHSE 321 Score = 40.8 bits (94), Expect = 0.003 Identities = 42/168 (25%), Positives = 71/168 (42%), Gaps = 8/168 (4%) Frame = +2 Query: 11 GPTGWVSCVRFSP---NNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSP 181 G T +V + +P N FA S S DR++KVW L + TL+GH V+ + Sbjct: 140 GHTHYVMQIVINPKDNNQFA----SASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYS 195 Query: 182 DGS--LCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLC--FSPNRYWLCAATQD-SIK 346 G SG D + +WD + +L+ G N C F P + ++D +++ Sbjct: 196 GGDKPYLISGADDRLVKIWDYQNKTCVQTLE-GHAQNVSCASFHPELPIIITGSEDGTVR 254 Query: 347 IWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTI 490 IW + + L + M C++ + + GY +G+I Sbjct: 255 IWHSSTYRLESTL-------NYGMERVWCVASLRGSNNVALGYDEGSI 295
>COPB2_HUMAN (P35606) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| (p102) Length = 905 Score = 55.8 bits (133), Expect = 8e-08 Identities = 45/179 (25%), Positives = 76/179 (42%), Gaps = 7/179 (3%) Frame = +2 Query: 23 WVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCT--LDGHGGYVSAVAVSP-DGSL 193 ++ C+ P P I++ S D +K+W+ K C+ +GH YV + ++P D + Sbjct: 100 YIRCIAVHPTQ--PFILTSSDDMLIKLWDWDK-KWSCSQVFEGHTHYVMQIVINPKDNNQ 156 Query: 194 CASGGKDGVTLLWDLTEGKRLYSLDAG----SIINSLCFSPNRYWLCAATQDSIKIWDLE 361 AS D +W L ++L+ + I+ Y + A +KIWD + Sbjct: 157 FASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQ 216 Query: 362 SKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISGFSYSS*IMY 538 +K VQ L S C S+ + + G DGT+RI+ S + S + Y Sbjct: 217 NKTCVQTLEGHAQNVS-------CASFHPELPIIITGSEDGTVRIWHSSTYRLESTLNY 268 Score = 51.6 bits (122), Expect = 1e-06 Identities = 37/153 (24%), Positives = 68/153 (44%), Gaps = 1/153 (0%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 V+C+ + P ++SG+ DR VK+W+ N TL+GH VS + P+ + +G Sbjct: 187 VNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITG 246 Query: 206 GKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKI-WDLESKHIVQD 382 +DG +W Y L+ ++L + R W A+ + S + + I+ Sbjct: 247 SEDGTVRIWH----SSTYRLE-----STLNYGMERVWCVASLRGSNNVALGYDEGSIIVK 297 Query: 383 LRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTD 481 L E P +S A+G ++A +++ Sbjct: 298 LGREEP----------AMSMDANGKIIWAKHSE 320 Score = 40.8 bits (94), Expect = 0.003 Identities = 42/168 (25%), Positives = 71/168 (42%), Gaps = 8/168 (4%) Frame = +2 Query: 11 GPTGWVSCVRFSP---NNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSP 181 G T +V + +P N FA S S DR++KVW L + TL+GH V+ + Sbjct: 139 GHTHYVMQIVINPKDNNQFA----SASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYS 194 Query: 182 DGS--LCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLC--FSPNRYWLCAATQD-SIK 346 G SG D + +WD + +L+ G N C F P + ++D +++ Sbjct: 195 GGDKPYLISGADDRLVKIWDYQNKTCVQTLE-GHAQNVSCASFHPELPIIITGSEDGTVR 253 Query: 347 IWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTI 490 IW + + L + M C++ + + GY +G+I Sbjct: 254 IWHSSTYRLESTL-------NYGMERVWCVASLRGSNNVALGYDEGSI 294
>COPB2_BOVIN (P35605) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| (p102) Length = 905 Score = 55.8 bits (133), Expect = 8e-08 Identities = 45/179 (25%), Positives = 76/179 (42%), Gaps = 7/179 (3%) Frame = +2 Query: 23 WVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCT--LDGHGGYVSAVAVSP-DGSL 193 ++ C+ P P I++ S D +K+W+ K C+ +GH YV + ++P D + Sbjct: 100 YIRCIAVHPTQ--PFILTSSDDMLIKLWDWDK-KWSCSQVFEGHTHYVMQIVINPKDNNQ 156 Query: 194 CASGGKDGVTLLWDLTEGKRLYSLDAG----SIINSLCFSPNRYWLCAATQDSIKIWDLE 361 AS D +W L ++L+ + I+ Y + A +KIWD + Sbjct: 157 FASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQ 216 Query: 362 SKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISGFSYSS*IMY 538 +K VQ L S C S+ + + G DGT+RI+ S + S + Y Sbjct: 217 NKTCVQTLEGHAQNVS-------CASFHPELPIIITGSEDGTVRIWHSSTYRLESTLNY 268 Score = 51.6 bits (122), Expect = 1e-06 Identities = 37/153 (24%), Positives = 68/153 (44%), Gaps = 1/153 (0%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 V+C+ + P ++SG+ DR VK+W+ N TL+GH VS + P+ + +G Sbjct: 187 VNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITG 246 Query: 206 GKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKI-WDLESKHIVQD 382 +DG +W Y L+ ++L + R W A+ + S + + I+ Sbjct: 247 SEDGTVRIWH----SSTYRLE-----STLNYGMERVWCVASLRGSNNVALGYDEGSIIVK 297 Query: 383 LRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTD 481 L E P +S A+G ++A +++ Sbjct: 298 LGREEP----------AMSMDANGKIIWAKHSE 320 Score = 40.8 bits (94), Expect = 0.003 Identities = 42/168 (25%), Positives = 71/168 (42%), Gaps = 8/168 (4%) Frame = +2 Query: 11 GPTGWVSCVRFSP---NNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSP 181 G T +V + +P N FA S S DR++KVW L + TL+GH V+ + Sbjct: 139 GHTHYVMQIVINPKDNNQFA----SASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYS 194 Query: 182 DGS--LCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLC--FSPNRYWLCAATQD-SIK 346 G SG D + +WD + +L+ G N C F P + ++D +++ Sbjct: 195 GGDKPYLISGADDRLVKIWDYQNKTCVQTLE-GHAQNVSCASFHPELPIIITGSEDGTVR 253 Query: 347 IWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTI 490 IW + + L + M C++ + + GY +G+I Sbjct: 254 IWHSSTYRLESTL-------NYGMERVWCVASLRGSNNVALGYDEGSI 294
>MORG1_RAT (Q5BLX8) Mitogen-activated protein kinase organizer 1 (MAPK| organizer 1) Length = 315 Score = 55.8 bits (133), Expect = 8e-08 Identities = 51/166 (30%), Positives = 77/166 (46%), Gaps = 4/166 (2%) Frame = +2 Query: 20 GWVSCVRFSPN-NFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLC 196 G V VRF+ + N+ T S D+++K+WN L T GHG V A S D S Sbjct: 26 GAVRAVRFNVDGNYCLTCGS---DKTLKLWNPLRGTLLRTYSGHGYEVLDAAGSFDNSHL 82 Query: 197 ASGGKDGVTLLWDLTEGK--RLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLESK 367 SGG D +LWD+ G+ R + AG +N++ F+ + + + D S++ WD S+ Sbjct: 83 CSGGGDKTVVLWDVATGQVVRKFRGHAGK-VNTVQFNEEATVILSGSIDSSVRCWDCRSR 141 Query: 368 HIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 +PE PV + S + AG DG +R Y + Sbjct: 142 ------KPE-PVQTLDEARDGISSVKVSDHEILAGSVDGRVRRYDL 180 Score = 37.7 bits (86), Expect = 0.022 Identities = 23/87 (26%), Positives = 39/87 (44%), Gaps = 2/87 (2%) Frame = +2 Query: 134 TLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGK--RLYSLDAGSIINSLCFSPN 307 TLD G V AV + DG+ C + G D LW+ G R YS ++++ N Sbjct: 20 TLDCGQGAVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGTLLRTYSGHGYEVLDAAGSFDN 79 Query: 308 RYWLCAATQDSIKIWDLESKHIVQDLR 388 + ++ +WD+ + +V+ R Sbjct: 80 SHLCSGGGDKTVVLWDVATGQVVRKFR 106 Score = 36.2 bits (82), Expect = 0.065 Identities = 32/116 (27%), Positives = 52/116 (44%), Gaps = 3/116 (2%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGG--YVSAVAVSPDGSLCA 199 ++C FS + T++S S D ++++ + +L GH Y +S + Sbjct: 194 ITCTCFSRDGQC-TLIS-SLDSTLRLLDKDTGELLGEYVGHKNQKYKLDCCLSERDTHVV 251 Query: 200 SGGKDGVTLLWDLTEGKRLYSLDAGS-IINSLCFSPNRYWLCAATQDSIKIWDLES 364 S +DG WDL EG +L GS ++ SL + P L A SI+ W E+ Sbjct: 252 SCSEDGKVFFWDLVEGSLALALPVGSNVVQSLAYHPADPCLLTAMGGSIQYWREET 307
>MORG1_MOUSE (Q9DAJ4) Mitogen-activated protein kinase organizer 1 (MAPK| organizer 1) Length = 315 Score = 55.8 bits (133), Expect = 8e-08 Identities = 51/166 (30%), Positives = 77/166 (46%), Gaps = 4/166 (2%) Frame = +2 Query: 20 GWVSCVRFSPN-NFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLC 196 G V VRF+ + N+ T S D+++K+WN L T GHG V A S D S Sbjct: 26 GAVRAVRFNVDGNYCLTCGS---DKTLKLWNPLRGTLLRTYSGHGYEVLDAAGSFDNSHL 82 Query: 197 ASGGKDGVTLLWDLTEGK--RLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLESK 367 SGG D +LWD+ G+ R + AG +N++ F+ + + + D S++ WD S+ Sbjct: 83 CSGGGDKTVVLWDVATGQVVRKFRGHAGK-VNTVQFNEEATVILSGSIDSSVRCWDCRSR 141 Query: 368 HIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 +PE PV + S + AG DG +R Y + Sbjct: 142 ------KPE-PVQTLDEARDGISSVKVSDHEILAGSVDGRVRRYDL 180 Score = 38.1 bits (87), Expect = 0.017 Identities = 23/87 (26%), Positives = 39/87 (44%), Gaps = 2/87 (2%) Frame = +2 Query: 134 TLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGK--RLYSLDAGSIINSLCFSPN 307 TLD G V AV + DG+ C + G D LW+ G R YS ++++ N Sbjct: 20 TLDCSQGAVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGTLLRTYSGHGYEVLDAAGSFDN 79 Query: 308 RYWLCAATQDSIKIWDLESKHIVQDLR 388 + ++ +WD+ + +V+ R Sbjct: 80 SHLCSGGGDKTVVLWDVATGQVVRKFR 106 Score = 37.4 bits (85), Expect = 0.029 Identities = 32/116 (27%), Positives = 52/116 (44%), Gaps = 3/116 (2%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGG--YVSAVAVSPDGSLCA 199 ++C FS + T++S S D ++++ + +L GH Y +S + Sbjct: 194 ITCTCFSRDGQC-TLIS-SLDSTLRLLDKDTGELLGEYVGHKNQQYKLDCCLSERDTHVV 251 Query: 200 SGGKDGVTLLWDLTEGKRLYSLDAGS-IINSLCFSPNRYWLCAATQDSIKIWDLES 364 S +DG WDL EG +L GS ++ SL + P L A SI+ W E+ Sbjct: 252 SCSEDGKVFFWDLVEGALALALPVGSNVVQSLAYHPTEPCLLTAMGGSIQYWREET 307
>SLP1_SCHPO (P78972) WD-repeat-containing protein slp1| Length = 488 Score = 55.8 bits (133), Expect = 8e-08 Identities = 39/152 (25%), Positives = 73/152 (48%), Gaps = 6/152 (3%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSP-DGSLCASGG--KDGVTLLWDL 238 + SG D V++W+ + + T H V AVA P +L A+GG D W+ Sbjct: 319 LASGGNDNVVQIWDARSSIPKFTKTNHNAAVKAVAWCPWQSNLLATGGGTMDKQIHFWNA 378 Query: 239 TEGKRLYSLDAGSIINSLCFSPNRYWLCAA---TQDSIKIWDLESKHIVQDLRPEVPVSS 409 G R+ ++DAGS + SL +SP+ + + +++ IW S + + + ++P Sbjct: 379 ATGARVNTVDAGSQVTSLIWSPHSKEIMSTHGFPDNNLSIWSYSSSGLTKQV--DIPAHD 436 Query: 410 KQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 ++LY + S DG L +D ++ +++ Sbjct: 437 TRVLYS---ALSPDGRILSTAASDENLKFWRV 465 Score = 40.4 bits (93), Expect = 0.003 Identities = 34/145 (23%), Positives = 66/145 (45%), Gaps = 1/145 (0%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLD-GHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTE 244 +V+ + +R+V VWN + + + YV++V S DGS + G +G+ ++D+ Sbjct: 193 VVAVALERNVYVWNADSGSVSALAETDESTYVASVKWSHDGSFLSVGLGNGLVDIYDVES 252 Query: 245 GKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLY 424 +L ++ AG C S NR+ L + ++ H V+ ++ Sbjct: 253 QTKLRTM-AGHQARVGCLSWNRHVLSSGSRSGAI-----HHHDVRIANHQIGTLQGHSSE 306 Query: 425 CTCLSWSADGSTLYAGYTDGTIRIY 499 L+W +DG L +G D ++I+ Sbjct: 307 VCGLAWRSDGLQLASGGNDNVVQIW 331 Score = 30.0 bits (66), Expect = 4.6 Identities = 20/85 (23%), Positives = 36/85 (42%), Gaps = 4/85 (4%) Frame = +2 Query: 263 LDAGSIINSLCFS----PNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCT 430 LDA II+ + N + A + ++ +W+ +S + + + Y Sbjct: 172 LDAPGIIDDYYLNLLDWSNLNVVAVALERNVYVWNADSGSV------SALAETDESTYVA 225 Query: 431 CLSWSADGSTLYAGYTDGTIRIYKI 505 + WS DGS L G +G + IY + Sbjct: 226 SVKWSHDGSFLSVGLGNGLVDIYDV 250
>WSB1_MOUSE (O54927) WD repeat and SOCS box-containing protein 1 (WSB-1)| Length = 421 Score = 55.5 bits (132), Expect = 1e-07 Identities = 47/169 (27%), Positives = 73/169 (43%), Gaps = 8/169 (4%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG 187 R WV FSP+ + S ++V +WN+ + L+GH V A SPDG Sbjct: 211 RAHQNWVYSCAFSPD--CSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVACDFSPDG 268 Query: 188 SLCASGGKDGVTLLWDLTEGKRLYSLDAGSIINS----LCFSPNRYWLCAA--TQDSIKI 349 +L A+ D +WD G L ++ G + S N W+ A + D + + Sbjct: 269 ALLATASYDTRVYVWDPHNGDLL--MEFGHLFPSPTPIFAGGANDRWVRAVSFSHDGLHV 326 Query: 350 WDLESKHIVQDLR--PEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTI 490 L +V+ R + PV + C ++S DGS L AG DG++ Sbjct: 327 ASLADDKMVRFWRIDEDCPVQVAPLSNGLCCAFSTDGSVLAAGTHDGSV 375 Score = 45.1 bits (105), Expect = 1e-04 Identities = 42/164 (25%), Positives = 74/164 (45%), Gaps = 14/164 (8%) Frame = +2 Query: 56 FAPT----IVSGSWDRSVKVWNLTNC-KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGV 220 FAP +VS S D++++VW+L + + L H +V + A SPD S+ S G Sbjct: 178 FAPDGSLLLVSASRDKTLRVWDLKDDGNMVKVLRAHQNWVYSCAFSPDCSMLCSVGASKA 237 Query: 221 TLLWDLTEGKRLYSLDAGSIINSLC-FSPNRYWLCAATQDS-IKIWD-------LESKHI 373 LW++ + + L+ C FSP+ L A+ D+ + +WD +E H+ Sbjct: 238 VFLWNMDKYTMIRKLEGHHHDVVACDFSPDGALLATASYDTRVYVWDPHNGDLLMEFGHL 297 Query: 374 VQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 P + + +S+S DG + + D +R ++I Sbjct: 298 FPSPTP-IFAGGANDRWVRAVSFSHDGLHVASLADDKMVRFWRI 340 Score = 40.4 bits (93), Expect = 0.003 Identities = 29/110 (26%), Positives = 55/110 (50%), Gaps = 4/110 (3%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS-LCASGGKDGVTLLWDL-T 241 + +G + +K+W++ KL L H V + +PDGS L S +D +WDL Sbjct: 143 LATGLNNGRIKIWDVYTGKLLLNLVDHIEMVRDLTFAPDGSLLLVSASRDKTLRVWDLKD 202 Query: 242 EGKRLYSLDA-GSIINSLCFSPNRYWLCA-ATQDSIKIWDLESKHIVQDL 385 +G + L A + + S FSP+ LC+ ++ +W+++ +++ L Sbjct: 203 DGNMVKVLRAHQNWVYSCAFSPDCSMLCSVGASKAVFLWNMDKYTMIRKL 252
>TLE2_BRARE (O13166) Groucho 2 protein| Length = 761 Score = 55.5 bits (132), Expect = 1e-07 Identities = 30/85 (35%), Positives = 41/85 (48%) Frame = +2 Query: 86 DRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSL 265 D ++ VW+L N L GH S + +S DG+ +GG D WDL EG++L Sbjct: 586 DGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQH 645 Query: 266 DAGSIINSLCFSPNRYWLCAATQDS 340 D S I SL + P WL + S Sbjct: 646 DFASQIFSLGYCPTGEWLAVGMESS 670 Score = 44.7 bits (104), Expect = 2e-04 Identities = 33/148 (22%), Positives = 63/148 (42%), Gaps = 11/148 (7%) Frame = +2 Query: 95 VKVWNLTN-------CKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL---TE 244 VK+W+++ +L C Y+ + + PDG GG+ +WDL T Sbjct: 498 VKIWDISQPGSKSPVSQLDCL--NRDNYIRSCKLLPDGRTLIVGGEASTLTIWDLASQTP 555 Query: 245 GKRLYSLDAGSIINSLCFSPN-RYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQML 421 + + +L SP+ + + +I +WDL ++ +V+ + +S Sbjct: 556 RIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGAS---- 611 Query: 422 YCTCLSWSADGSTLYAGYTDGTIRIYKI 505 C+ S DG+ L+ G D T+R + + Sbjct: 612 ---CIDISHDGTKLWTGGLDNTVRSWDL 636 Score = 37.4 bits (85), Expect = 0.029 Identities = 29/135 (21%), Positives = 56/135 (41%), Gaps = 5/135 (3%) Frame = +2 Query: 65 TIVSGSWDRSVKVWNLTNC--KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL 238 T++ G ++ +W+L + +++ L A+A+SPD +C S DG +WDL Sbjct: 535 TLIVGGEASTLTIWDLASQTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDL 594 Query: 239 ---TEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSS 409 T ++ G+ + + W ++++ WDL +Q + + Sbjct: 595 HNQTLVRQFQGHTDGASCIDISHDGTKLW-TGGLDNTVRSWDLREGRQLQ--QHDFASQI 651 Query: 410 KQMLYCTCLSWSADG 454 + YC W A G Sbjct: 652 FSLGYCPTGEWLAVG 666
>GBB_SOLTU (P93563) Guanine nucleotide-binding protein beta subunit| Length = 377 Score = 55.5 bits (132), Expect = 1e-07 Identities = 50/175 (28%), Positives = 75/175 (42%), Gaps = 8/175 (4%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNL-TNCKLRCTLDGHGGYVSAVAVSPDG 187 G T V V S +N VSGS D + ++W+ + + T GH V+ V PDG Sbjct: 202 GHTADVLSVSISSSN-PKLFVSGSCDTTARLWDTRVASRAQRTFHGHESDVNTVKFFPDG 260 Query: 188 SLCASGGKDGVTLLWDLTEGKRL--YSLDAGS----IINSLCFS-PNRYWLCAATQDSIK 346 + +G DG L+D+ G +L Y+ G + S+ FS R + Sbjct: 261 NRFGTGSDDGSCRLFDIRTGHQLQVYNQPHGDGDIPHVTSMAFSISGRLLFVGYSNGDCY 320 Query: 347 IWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISG 511 +WD +V +L V + +CL SADGS L G D ++I+ G Sbjct: 321 VWDTLLAKVVLNLG---SVQNSHEGRISCLGLSADGSALCTGSWDTNLKIWAFGG 372 Score = 30.8 bits (68), Expect = 2.7 Identities = 29/141 (20%), Positives = 58/141 (41%), Gaps = 2/141 (1%) Frame = +2 Query: 44 SPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVT 223 SP F PT +L C++ L GH G V ++ +P+ + S +DG Sbjct: 46 SPVTFGPT-------------DLVCCRI---LQGHTGKVYSLDWTPEKNRIVSASQDGRL 89 Query: 224 LLWDLTEGKRLYSLDAG-SIINSLCFSPN-RYWLCAATQDSIKIWDLESKHIVQDLRPEV 397 ++W+ ++ +++ + + + FSP+ + C + I++L S + P Sbjct: 90 IVWNALTSQKTHAIKLPCAWVMTCAFSPSGQSVACGGLDSACSIFNLNSPIDKDGIHPVS 149 Query: 398 PVSSKQMLYCTCLSWSADGST 460 + S Y + + D T Sbjct: 150 RMLSGHKGYVSSCQYVPDEDT 170
>WDR1_CAEEL (Q11176) Actin-interacting protein 1 (AIP1) (Uncoordinated protein| 78) Length = 611 Score = 55.5 bits (132), Expect = 1e-07 Identities = 52/193 (26%), Positives = 84/193 (43%), Gaps = 46/193 (23%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 I+SGS D +V ++ K + T H +V +V +PDGSL AS G DG +L++ +G Sbjct: 163 IISGSDDNTVAIFEGPPFKFKSTFGEHTKFVHSVRYNPDGSLFASTGGDGTIVLYNGVDG 222 Query: 248 KRLYSLDAGSIIN--------SLCFSPNRYWLCAATQD-SIKIWD--------------- 355 + + S+ N L +SP+ + +A+ D +IKIW+ Sbjct: 223 TKTGVFEDDSLKNVAHSGSVFGLTWSPDGTKIASASADKTIKIWNVATLKVEKTIPVGTR 282 Query: 356 -----------------LESKHIVQDLRPEVPVSSKQMLY-----CTCLSWSADGSTLYA 469 + + + + PE+ S Q+ Y T LS SADG TL++ Sbjct: 283 IEDQQLGIIWTKQALVSISANGFINFVNPELG-SIDQVRYGHNKAITALSSSADGKTLFS 341 Query: 470 GYTDGTIRIYKIS 508 +G I + IS Sbjct: 342 ADAEGHINSWDIS 354 Score = 30.4 bits (67), Expect = 3.6 Identities = 22/76 (28%), Positives = 38/76 (50%), Gaps = 5/76 (6%) Frame = +2 Query: 146 HGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKR----LYSLDAGSIINSLCFSPNRY 313 H V+ V+ SPD A+G D ++W++ + + A S +NS+ + N Sbjct: 535 HTAKVACVSWSPDNVRLATGSLDNSVIVWNMNKPSDHPIIIKGAHAMSSVNSVIWL-NET 593 Query: 314 WLCAATQDS-IKIWDL 358 + +A QDS IK W++ Sbjct: 594 TIVSAGQDSNIKFWNV 609 Score = 29.6 bits (65), Expect = 6.1 Identities = 16/51 (31%), Positives = 24/51 (47%) Frame = +2 Query: 92 SVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTE 244 +V V +LT+ ++ H + SP G CASG G +WD T+ Sbjct: 43 TVPVGSLTDTEIYTE---HSHQTTVAKTSPSGYYCASGDVHGNVRIWDTTQ 90
>UTP15_XENLA (Q7ZXZ2) U3 small nucleolar RNA-associated protein 15 homolog| Length = 515 Score = 55.1 bits (131), Expect = 1e-07 Identities = 45/168 (26%), Positives = 75/168 (44%), Gaps = 8/168 (4%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSP-DGSLCASGGKDGVTLLWDLTE 244 IVSGS D + K+W++ N + H Y+ S + L A+G D ++D Sbjct: 137 IVSGSDDYTSKLWDIPNGIEIASYKEHTDYIRCGCTSSLNNDLFATGSYDHTIKVFDGRT 196 Query: 245 GKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWD-LESKHIVQDLRPEVPVSSKQML 421 K + S+D G + S+ P+ L +A +K+WD L+ ++ LR Sbjct: 197 DKSVMSMDHGQPVESVLLFPSGGLLVSAGGRYVKVWDILKGGQLLVSLR-------NHHK 249 Query: 422 YCTCLSWSADGSTLYAGYTDGTIRIYK------ISGFSYSS*IMYLVL 547 TCL S+ G L +G D +++Y + F Y++ I+ L L Sbjct: 250 TVTCLCLSSSGQRLLSGSLDRHVKVYSTMNYKVVHSFDYAASILSLAL 297 Score = 32.3 bits (72), Expect = 0.94 Identities = 20/65 (30%), Positives = 37/65 (56%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 V+C+ S + ++SGS DR VKV++ N K+ + D + + ++A++PD + G Sbjct: 251 VTCLCLSSSG--QRLLSGSLDRHVKVYSTMNYKVVHSFD-YAASILSLALAPDDQMIVVG 307 Query: 206 GKDGV 220 +GV Sbjct: 308 MTNGV 312
>SPG16_HUMAN (Q8N0X2) Sperm-associated antigen 16 protein (PF20 protein homolog)| Length = 631 Score = 55.1 bits (131), Expect = 1e-07 Identities = 47/165 (28%), Positives = 79/165 (47%), Gaps = 2/165 (1%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G T V+ + F P F+ T+++ S D+++ +W+ +L GH ++ P G Sbjct: 476 GHTDSVNSIEFFP--FSNTLLTSSADKTLSIWDARTGICEQSLYGHMHSINDAIFDPRGH 533 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAG-SIINSLCF-SPNRYWLCAATQDSIKIWDLES 364 + AS GVT LWD + + S+D G S N + F S R A+ I + DL+S Sbjct: 534 MIASCDACGVTKLWDFRKLLPIVSIDIGPSPGNEVNFDSSGRVLAQASGNGVIHLLDLKS 593 Query: 365 KHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 I + + E + + +S DG L++G +DGT+R + Sbjct: 594 GEIHKLMGHENEAHT--------VVFSHDGEILFSGGSDGTVRTW 630 Score = 48.1 bits (113), Expect = 2e-05 Identities = 31/111 (27%), Positives = 50/111 (45%), Gaps = 2/111 (1%) Frame = +2 Query: 29 SCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGG 208 SC S NF + S S D++ K+W++ + + RCTL GH V+++ P + + Sbjct: 441 SCTWHSCGNF---VASSSLDKTSKIWDVNSERCRCTLYGHTDSVNSIEFFPFSNTLLTSS 497 Query: 209 KDGVTLLWDLTEGKRLYSLDAG-SIINSLCFSPNRYWLCAATQDSI-KIWD 355 D +WD G SL IN F P + + + + K+WD Sbjct: 498 ADKTLSIWDARTGICEQSLYGHMHSINDAIFDPRGHMIASCDACGVTKLWD 548 Score = 47.0 bits (110), Expect = 4e-05 Identities = 33/116 (28%), Positives = 50/116 (43%), Gaps = 2/116 (1%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 VSCV P+ +VS DR KV L C + T GH ++S P G A+ Sbjct: 355 VSCVSMQPHK--DILVSCGEDRLWKVLGLPKCNVLLTGFGHTDWLSDCCFHPSGDKLATS 412 Query: 206 GKDGVTLLWDLTEGKRLYSLDAGS--IINSLCFSPNRYWLCAATQDSIKIWDLESK 367 D LWDL G + + + S + + S + ++ + KIWD+ S+ Sbjct: 413 SGDTTVKLWDLCTGDCILTFEGHSRAVWSCTWHSCGNFVASSSLDKTSKIWDVNSE 468
>PRP46_DEBHA (Q6BU94) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 417 Score = 55.1 bits (131), Expect = 1e-07 Identities = 46/169 (27%), Positives = 69/169 (40%), Gaps = 7/169 (4%) Frame = +2 Query: 20 GWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCA 199 GWV P V+GS D ++K+W+L + L+ T+ GH V ++AVS Sbjct: 122 GWVRSCTVDPVT-NKWFVTGSSDSTIKIWDLASLNLKATITGHIMGVRSLAVSSRYPYLF 180 Query: 200 SGGKDGVTLLWDLTEGKRLYSLDAGSI------INSLCFSPNRYWLCAATQDS-IKIWDL 358 SG +D WDL L + I ++ P L +DS I++WDL Sbjct: 181 SGSEDKTVKCWDLERTNSLLGCQIRNYHGHVGGIYAMALHPELDLLFTGGRDSVIRVWDL 240 Query: 359 ESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 S R E+ V S T ++ + D TIR++ I Sbjct: 241 RS-------RTEIMVLSGHRSDITSIASQIGDPQIITSSMDATIRLWDI 282 Score = 52.8 bits (125), Expect = 7e-07 Identities = 52/207 (25%), Positives = 89/207 (42%), Gaps = 46/207 (22%) Frame = +2 Query: 17 TGWVSCVR-FSPNNFAPTIVSGSWDRSVKVWNL--TNCKLRCTL---DGHGGYVSAVAVS 178 TG + VR + ++ P + SGS D++VK W+L TN L C + GH G + A+A+ Sbjct: 161 TGHIMGVRSLAVSSRYPYLFSGSEDKTVKCWDLERTNSLLGCQIRNYHGHVGGIYAMALH 220 Query: 179 PDGSLCASGGKDGVTLLWDLTEGKRLYSLDAG-SIINSLCFSPNRYWLCAATQDS-IKIW 352 P+ L +GG+D V +WDL + L S I S+ + ++ D+ I++W Sbjct: 221 PELDLLFTGGRDSVIRVWDLRSRTEIMVLSGHRSDITSIASQIGDPQIITSSMDATIRLW 280 Query: 353 DLESK-------HIVQDLRPEVPVSSKQMLYCT--------------------------- 430 D+ H + +R + + ++M C+ Sbjct: 281 DIRKATTQLALTHHSKSIRL-MAMHPQEMTMCSGDTSGNLKEWLLPGGELLNEFGHSGEN 339 Query: 431 ----CLSWSADGSTLYAGYTDGTIRIY 499 LS + +TL++GY DG + Y Sbjct: 340 KIINTLSINPSNNTLFSGYDDGRMEFY 366
>TLE4_MOUSE (Q62441) Transducin-like enhancer protein 4 (Groucho-related| protein 4) (Grg-4) Length = 766 Score = 55.1 bits (131), Expect = 1e-07 Identities = 30/85 (35%), Positives = 42/85 (49%) Frame = +2 Query: 86 DRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSL 265 D ++ VW+L N L GH S + +S DG+ +GG D WDL EG++L Sbjct: 591 DGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQH 650 Query: 266 DAGSIINSLCFSPNRYWLCAATQDS 340 D S I SL + P WL ++S Sbjct: 651 DFTSQIFSLGYCPTGEWLAVGMENS 675 Score = 45.1 bits (105), Expect = 1e-04 Identities = 34/148 (22%), Positives = 64/148 (43%), Gaps = 11/148 (7%) Frame = +2 Query: 95 VKVWNLTN-------CKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL---TE 244 VKVW++++ +L C Y+ + + PDG GG+ +WDL T Sbjct: 503 VKVWDISHPGNKSPVSQLDCL--NRDNYIRSCRLLPDGRTLIVGGEASTLSIWDLAAPTP 560 Query: 245 GKRLYSLDAGSIINSLCFSPN-RYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQML 421 + + +L SP+ + + +I +WDL ++ +V+ + +S Sbjct: 561 RIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGAS---- 616 Query: 422 YCTCLSWSADGSTLYAGYTDGTIRIYKI 505 C+ S DG+ L+ G D T+R + + Sbjct: 617 ---CIDISNDGTKLWTGGLDNTVRSWDL 641 Score = 36.6 bits (83), Expect = 0.050 Identities = 29/135 (21%), Positives = 55/135 (40%), Gaps = 5/135 (3%) Frame = +2 Query: 65 TIVSGSWDRSVKVWNLT--NCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL 238 T++ G ++ +W+L +++ L A+A+SPD +C S DG +WDL Sbjct: 540 TLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDL 599 Query: 239 ---TEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSS 409 T ++ G+ + + W ++++ WDL +Q + + Sbjct: 600 HNQTLVRQFQGHTDGASCIDISNDGTKLW-TGGLDNTVRSWDLREGRQLQ--QHDFTSQI 656 Query: 410 KQMLYCTCLSWSADG 454 + YC W A G Sbjct: 657 FSLGYCPTGEWLAVG 671
>TLE4_HUMAN (Q04727) Transducin-like enhancer protein 4| Length = 766 Score = 55.1 bits (131), Expect = 1e-07 Identities = 30/85 (35%), Positives = 42/85 (49%) Frame = +2 Query: 86 DRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSL 265 D ++ VW+L N L GH S + +S DG+ +GG D WDL EG++L Sbjct: 591 DGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQH 650 Query: 266 DAGSIINSLCFSPNRYWLCAATQDS 340 D S I SL + P WL ++S Sbjct: 651 DFTSQIFSLGYCPTGEWLAVGMENS 675 Score = 45.1 bits (105), Expect = 1e-04 Identities = 34/148 (22%), Positives = 64/148 (43%), Gaps = 11/148 (7%) Frame = +2 Query: 95 VKVWNLTN-------CKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL---TE 244 VKVW++++ +L C Y+ + + PDG GG+ +WDL T Sbjct: 503 VKVWDISHPGNKSPVSQLDCL--NRDNYIRSCRLLPDGRTLIVGGEASTLSIWDLAAPTP 560 Query: 245 GKRLYSLDAGSIINSLCFSPN-RYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQML 421 + + +L SP+ + + +I +WDL ++ +V+ + +S Sbjct: 561 RIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGAS---- 616 Query: 422 YCTCLSWSADGSTLYAGYTDGTIRIYKI 505 C+ S DG+ L+ G D T+R + + Sbjct: 617 ---CIDISNDGTKLWTGGLDNTVRSWDL 641 Score = 36.6 bits (83), Expect = 0.050 Identities = 29/135 (21%), Positives = 55/135 (40%), Gaps = 5/135 (3%) Frame = +2 Query: 65 TIVSGSWDRSVKVWNLT--NCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL 238 T++ G ++ +W+L +++ L A+A+SPD +C S DG +WDL Sbjct: 540 TLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDL 599 Query: 239 ---TEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSS 409 T ++ G+ + + W ++++ WDL +Q + + Sbjct: 600 HNQTLVRQFQGHTDGASCIDISNDGTKLW-TGGLDNTVRSWDLREGRQLQ--QHDFTSQI 656 Query: 410 KQMLYCTCLSWSADG 454 + YC W A G Sbjct: 657 FSLGYCPTGEWLAVG 671
>PRP4_ARATH (O22212) U4/U6 small nuclear ribonucleoprotein PRP4-like protein| Length = 554 Score = 55.1 bits (131), Expect = 1e-07 Identities = 32/99 (32%), Positives = 53/99 (53%), Gaps = 3/99 (3%) Frame = +2 Query: 80 SWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLY 259 S+D++ ++W++ +GH V +A DG+L AS G D + +WDL G+ + Sbjct: 358 SYDKTWRLWDINTGAELLLQEGHSRSVYGIAFQQDGALAASCGLDSLARVWDLRTGRSIL 417 Query: 260 SLDAGSI--INSLCFSPNRYWLCAATQDS-IKIWDLESK 367 G I + S+ FSPN Y L + +D+ +IWDL + Sbjct: 418 VFQ-GHIKPVFSVNFSPNGYHLASGGEDNQCRIWDLRMR 455 Score = 54.3 bits (129), Expect = 2e-07 Identities = 44/146 (30%), Positives = 69/146 (47%), Gaps = 4/146 (2%) Frame = +2 Query: 86 DRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSL 265 D +VW+L + GH V +V SP+G ASGG+D +WDL K LY + Sbjct: 402 DSLARVWDLRTGRSILVFQGHIKPVFSVNFSPNGYHLASGGEDNQCRIWDLRMRKSLYII 461 Query: 266 DA-GSIINSLCFSPNR-YWLCAATQD-SIKIWDLESKHIVQDLR-PEVPVSSKQMLYCTC 433 A ++++ + + P Y+L A+ D + IW +V+ L E V+S Sbjct: 462 PAHANLVSQVKYEPQEGYFLATASYDMKVNIWSGRDFSLVKSLAGHESKVAS-------- 513 Query: 434 LSWSADGSTLYAGYTDGTIRIYKISG 511 L +AD S + D TI+++ SG Sbjct: 514 LDITADSSCIATVSHDRTIKLWTSSG 539 Score = 43.9 bits (102), Expect = 3e-04 Identities = 41/160 (25%), Positives = 71/160 (44%), Gaps = 3/160 (1%) Frame = +2 Query: 35 VRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKD 214 V FSP + + + S DR+ K+W T+ L T +GH ++ VA P G + D Sbjct: 304 VVFSPVD--DCLATASADRTAKLWK-TDGTLLQTFEGHLDRLARVAFHPSGKYLGTTSYD 360 Query: 215 GVTLLWDLTEGKRLYSLDAGS-IINSLCFSPNRYWLCAATQDSI-KIWDLESKHIVQDLR 388 LWD+ G L + S + + F + + DS+ ++WDL + + + Sbjct: 361 KTWRLWDINTGAELLLQEGHSRSVYGIAFQQDGALAASCGLDSLARVWDLRTGRSILVFQ 420 Query: 389 PEV-PVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 + PV S +++S +G L +G D RI+ + Sbjct: 421 GHIKPVFS--------VNFSPNGYHLASGGEDNQCRIWDL 452 Score = 33.5 bits (75), Expect = 0.42 Identities = 19/69 (27%), Positives = 34/69 (49%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 VS V++ P + + S+D V +W+ + L +L GH V+++ ++ D S A+ Sbjct: 468 VSQVKYEPQE-GYFLATASYDMKVNIWSGRDFSLVKSLAGHESKVASLDITADSSCIATV 526 Query: 206 GKDGVTLLW 232 D LW Sbjct: 527 SHDRTIKLW 535 Score = 30.0 bits (66), Expect = 4.6 Identities = 24/89 (26%), Positives = 40/89 (44%), Gaps = 6/89 (6%) Frame = +2 Query: 104 WNLTNCK---LRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSL--D 268 W L + K L C+ G ++ + S DG + A+ GVT LW++ + ++ D Sbjct: 237 WALKHAKHMALDCSNFGDDRPLTGCSFSRDGKILATCSLSGVTKLWEMPQVTNTIAVLKD 296 Query: 269 AGSIINSLCFSPNRYWLCAATQD-SIKIW 352 + FSP L A+ D + K+W Sbjct: 297 HKERATDVVFSPVDDCLATASADRTAKLW 325
>PRP46_KLULA (Q6CKE8) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 434 Score = 55.1 bits (131), Expect = 1e-07 Identities = 35/121 (28%), Positives = 60/121 (49%), Gaps = 2/121 (1%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G TGWV CV P + +GS D ++K+W+L KL+ TL GH V +A+S Sbjct: 120 GHTGWVRCVCVDPVD-NEWFATGSNDTTIKIWDLAAGKLKITLIGHVMSVRDIAISKRHP 178 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAG-SIINSLCFSPNRYWLCAATQDS-IKIWDLES 364 S +D + WDL + S ++++ P+ + A +D+ +++WD+ S Sbjct: 179 YMFSASEDKLVKCWDLERNTAIRDFHGHLSGVHTVDVHPSLDIIATAGRDAVVRLWDIRS 238 Query: 365 K 367 + Sbjct: 239 R 239 Score = 47.4 bits (111), Expect = 3e-05 Identities = 29/91 (31%), Positives = 46/91 (50%), Gaps = 4/91 (4%) Frame = +2 Query: 122 KLRCTLDGHGGYVSAVAVSP-DGSLCASGGKDGVTLLWDLTEGKRLYSLDAGSI--INSL 292 KL ++GH G+V V V P D A+G D +WDL GK +L G + + + Sbjct: 113 KLSKVINGHTGWVRCVCVDPVDNEWFATGSNDTTIKIWDLAAGKLKITL-IGHVMSVRDI 171 Query: 293 CFSPNRYWLCAATQDS-IKIWDLESKHIVQD 382 S ++ +A++D +K WDLE ++D Sbjct: 172 AISKRHPYMFSASEDKLVKCWDLERNTAIRD 202 Score = 38.1 bits (87), Expect = 0.017 Identities = 36/155 (23%), Positives = 61/155 (39%), Gaps = 2/155 (1%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 I + D V++W++ + L GH ++ V P S D LWD+ G Sbjct: 222 IATAGRDAVVRLWDIRSRSEIMVLPGHKSPINKVKCLPVDPQIISCSGDATVRLWDIIAG 281 Query: 248 KRLYSLDAGS-IINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLY 424 K L S I L P + + + + ++ W L ++ + + S+ Sbjct: 282 KASKVLTHHSRNIRDLTLHPAEFSFASVSTNDVRSWKLPEGQLLTNFQ------SQNTGI 335 Query: 425 CTCLSWSADGSTLYAGYTDGTIRIYKI-SGFSYSS 526 +S + D + L AG DGT+ Y +G Y S Sbjct: 336 LNTVSINHD-NVLLAGGDDGTLCFYDYKTGHKYQS 369
>PK1IP_HUMAN (Q9NWT1) p21-activated protein kinase-interacting protein 1| (PAK1-interacting protein 1) (PAK/PLC-interacting protein 1) (hPIP1) Length = 392 Score = 55.1 bits (131), Expect = 1e-07 Identities = 34/145 (23%), Positives = 69/145 (47%) Frame = +2 Query: 17 TGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLC 196 +G ++C++F N ++SG+ D + +W+ + ++ H G V+ +++ P G L Sbjct: 82 SGTITCLKFYGNRH---LISGAEDGLICIWDAKKWECLKSIKAHKGQVTFLSIHPSGKLA 138 Query: 197 ASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIV 376 S G D W+L EG+ + + + + +SP Q+ I I+ L++ I Sbjct: 139 LSVGTDKTLRTWNLVEGRSAFIKNIKQNAHIVEWSPRGEQYVVIIQNKIDIYQLDTASIS 198 Query: 377 QDLRPEVPVSSKQMLYCTCLSWSAD 451 + E +SS + L + L+ + D Sbjct: 199 GTITNEKRISSVKFLSESVLAVAGD 223
>TLE1_MOUSE (Q62440) Transducin-like enhancer protein 1 (Groucho-related| protein 1) (Grg-1) Length = 770 Score = 55.1 bits (131), Expect = 1e-07 Identities = 36/115 (31%), Positives = 52/115 (45%), Gaps = 1/115 (0%) Frame = +2 Query: 86 DRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSL 265 D ++ VW+L N L GH S + +S DG+ +GG D WDL EG++L Sbjct: 595 DGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQH 654 Query: 266 DAGSIINSLCFSPNRYWLCAATQDS-IKIWDLESKHIVQDLRPEVPVSSKQMLYC 427 D S I SL + P WL + S +++ + Q E V S + YC Sbjct: 655 DFTSQIFSLGYCPTGEWLAVGMESSNVEVLHVNKPDKYQLHLHESCVLSLKFAYC 709 Score = 45.1 bits (105), Expect = 1e-04 Identities = 34/148 (22%), Positives = 64/148 (43%), Gaps = 11/148 (7%) Frame = +2 Query: 95 VKVWNLTN-------CKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL---TE 244 VKVW++++ +L C Y+ + + PDG GG+ +WDL T Sbjct: 507 VKVWDISHPGNKSPVSQLDCL--NRDNYIRSCKLLPDGCTLIVGGEASTLSIWDLAAPTP 564 Query: 245 GKRLYSLDAGSIINSLCFSPN-RYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQML 421 + + +L SP+ + + +I +WDL ++ +V+ + +S Sbjct: 565 RIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGAS---- 620 Query: 422 YCTCLSWSADGSTLYAGYTDGTIRIYKI 505 C+ S DG+ L+ G D T+R + + Sbjct: 621 ---CIDISNDGTKLWTGGLDNTVRSWDL 645 Score = 36.6 bits (83), Expect = 0.050 Identities = 29/135 (21%), Positives = 55/135 (40%), Gaps = 5/135 (3%) Frame = +2 Query: 65 TIVSGSWDRSVKVWNLT--NCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL 238 T++ G ++ +W+L +++ L A+A+SPD +C S DG +WDL Sbjct: 544 TLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDL 603 Query: 239 ---TEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSS 409 T ++ G+ + + W ++++ WDL +Q + + Sbjct: 604 HNQTLVRQFQGHTDGASCIDISNDGTKLW-TGGLDNTVRSWDLREGRQLQ--QHDFTSQI 660 Query: 410 KQMLYCTCLSWSADG 454 + YC W A G Sbjct: 661 FSLGYCPTGEWLAVG 675
>TLE1_HUMAN (Q04724) Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog)| Length = 770 Score = 55.1 bits (131), Expect = 1e-07 Identities = 36/115 (31%), Positives = 52/115 (45%), Gaps = 1/115 (0%) Frame = +2 Query: 86 DRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSL 265 D ++ VW+L N L GH S + +S DG+ +GG D WDL EG++L Sbjct: 595 DGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQH 654 Query: 266 DAGSIINSLCFSPNRYWLCAATQDS-IKIWDLESKHIVQDLRPEVPVSSKQMLYC 427 D S I SL + P WL + S +++ + Q E V S + YC Sbjct: 655 DFTSQIFSLGYCPTGEWLAVGMESSNVEVLHVNKPDKYQLHLHESCVLSLKFAYC 709 Score = 45.1 bits (105), Expect = 1e-04 Identities = 34/148 (22%), Positives = 64/148 (43%), Gaps = 11/148 (7%) Frame = +2 Query: 95 VKVWNLTN-------CKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL---TE 244 VKVW++++ +L C Y+ + + PDG GG+ +WDL T Sbjct: 507 VKVWDISHPGNKSPVSQLDCL--NRDNYIRSCKLLPDGCTLIVGGEASTLSIWDLAAPTP 564 Query: 245 GKRLYSLDAGSIINSLCFSPN-RYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQML 421 + + +L SP+ + + +I +WDL ++ +V+ + +S Sbjct: 565 RIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGAS---- 620 Query: 422 YCTCLSWSADGSTLYAGYTDGTIRIYKI 505 C+ S DG+ L+ G D T+R + + Sbjct: 621 ---CIDISNDGTKLWTGGLDNTVRSWDL 645 Score = 36.6 bits (83), Expect = 0.050 Identities = 29/135 (21%), Positives = 55/135 (40%), Gaps = 5/135 (3%) Frame = +2 Query: 65 TIVSGSWDRSVKVWNLT--NCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL 238 T++ G ++ +W+L +++ L A+A+SPD +C S DG +WDL Sbjct: 544 TLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDL 603 Query: 239 ---TEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSS 409 T ++ G+ + + W ++++ WDL +Q + + Sbjct: 604 HNQTLVRQFQGHTDGASCIDISNDGTKLW-TGGLDNTVRSWDLREGRQLQ--QHDFTSQI 660 Query: 410 KQMLYCTCLSWSADG 454 + YC W A G Sbjct: 661 FSLGYCPTGEWLAVG 675
>TLE4_RAT (Q07141) Transducin-like enhancer protein 4 (ESP2 protein)| Length = 741 Score = 55.1 bits (131), Expect = 1e-07 Identities = 30/85 (35%), Positives = 42/85 (49%) Frame = +2 Query: 86 DRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSL 265 D ++ VW+L N L GH S + +S DG+ +GG D WDL EG++L Sbjct: 566 DGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQH 625 Query: 266 DAGSIINSLCFSPNRYWLCAATQDS 340 D S I SL + P WL ++S Sbjct: 626 DFTSQIFSLGYCPTGEWLAVGMENS 650 Score = 46.6 bits (109), Expect = 5e-05 Identities = 35/148 (23%), Positives = 64/148 (43%), Gaps = 11/148 (7%) Frame = +2 Query: 95 VKVWNLTN-------CKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL---TE 244 VKVW++T+ +L C Y+ + + PDG GG+ +WDL T Sbjct: 478 VKVWDITDPGNKSPVSQLDCL--NRDNYIRSCRLLPDGRTLIVGGEASTLSIWDLAAPTP 535 Query: 245 GKRLYSLDAGSIINSLCFSPN-RYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQML 421 + + +L SP+ + + +I +WDL ++ +V+ + +S Sbjct: 536 RIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGAS---- 591 Query: 422 YCTCLSWSADGSTLYAGYTDGTIRIYKI 505 C+ S DG+ L+ G D T+R + + Sbjct: 592 ---CIDISNDGTKLWTGGLDNTVRSWDL 616 Score = 36.6 bits (83), Expect = 0.050 Identities = 29/135 (21%), Positives = 55/135 (40%), Gaps = 5/135 (3%) Frame = +2 Query: 65 TIVSGSWDRSVKVWNLT--NCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL 238 T++ G ++ +W+L +++ L A+A+SPD +C S DG +WDL Sbjct: 515 TLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDL 574 Query: 239 ---TEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSS 409 T ++ G+ + + W ++++ WDL +Q + + Sbjct: 575 HNQTLVRQFQGHTDGASCIDISNDGTKLW-TGGLDNTVRSWDLREGRQLQ--QHDFTSQI 631 Query: 410 KQMLYCTCLSWSADG 454 + YC W A G Sbjct: 632 FSLGYCPTGEWLAVG 646
>GBB_MAIZE (P49178) Guanine nucleotide-binding protein beta subunit| Length = 380 Score = 55.1 bits (131), Expect = 1e-07 Identities = 49/177 (27%), Positives = 76/177 (42%), Gaps = 10/177 (5%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRC-TLDGHGGYVSAVAVSPDG 187 G T V V + +N VSGS D +V++W++ T GH V++V PDG Sbjct: 203 GHTADVQSVSINSSN-TNMFVSGSCDTTVRLWDIRIASRAVRTYHGHEDDVNSVKFFPDG 261 Query: 188 SLCASGGKDGVTLLWDLTEGKRL--YSLDAG------SIINSLCFS-PNRYWLCAATQDS 340 +G DG L+D+ G +L YS + + S+ FS R + Sbjct: 262 HRFGTGSDDGTCRLFDMRTGHQLQVYSREPDRNSNELPTVTSIAFSISGRLLFAGYSNGD 321 Query: 341 IKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISG 511 +WD +V +L + + +CL S+DGS L G D ++I+ SG Sbjct: 322 CYVWDTLLAEVVLNLG---NLQNSHDGRISCLGMSSDGSALCTGSWDKNLKIWAFSG 375 Score = 35.8 bits (81), Expect = 0.085 Identities = 37/176 (21%), Positives = 78/176 (44%), Gaps = 10/176 (5%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG 187 +G +G V + ++P IVS S D + VWN + + H +V A A +P+G Sbjct: 63 QGHSGKVYSLDWTPEK--NWIVSASQDGRLIVWNALTSQKTHAIKLHCPWVMACAFAPNG 120 Query: 188 SLCASGGKDGVTLLWDL-TEGKRLYSLDAGSI-------INSLCFSPNR--YWLCAATQD 337 A GG D +++L ++ R ++ I ++S + P++ + ++ Sbjct: 121 QSVACGGLDSACSIFNLNSQADRDGNMPVSRILTGHKGYVSSCQYVPDQETRLITSSGDQ 180 Query: 338 SIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 + +WD+ + + E P + ++ S++ + +G D T+R++ I Sbjct: 181 TCVLWDVTTGQRISIFGGEFPSGHTADVQSVSIN-SSNTNMFVSGSCDTTVRLWDI 235 Score = 32.3 bits (72), Expect = 0.94 Identities = 22/93 (23%), Positives = 45/93 (48%), Gaps = 2/93 (2%) Frame = +2 Query: 134 TLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLDAG-SIINSLCFSPN- 307 TL GH G V ++ +P+ + S +DG ++W+ ++ +++ + + F+PN Sbjct: 61 TLQGHSGKVYSLDWTPEKNWIVSASQDGRLIVWNALTSQKTHAIKLHCPWVMACAFAPNG 120 Query: 308 RYWLCAATQDSIKIWDLESKHIVQDLRPEVPVS 406 + C + I++L S+ D +PVS Sbjct: 121 QSVACGGLDSACSIFNLNSQ---ADRDGNMPVS 150
>TLE3_HUMAN (Q04726) Transducin-like enhancer protein 3 (ESG3)| Length = 772 Score = 54.7 bits (130), Expect = 2e-07 Identities = 30/85 (35%), Positives = 41/85 (48%) Frame = +2 Query: 86 DRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSL 265 D ++ VW+L N L GH S + +S DG+ +GG D WDL EG++L Sbjct: 597 DGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQH 656 Query: 266 DAGSIINSLCFSPNRYWLCAATQDS 340 D S I SL + P WL + S Sbjct: 657 DFTSQIFSLGYCPTGEWLAVGMESS 681 Score = 44.7 bits (104), Expect = 2e-04 Identities = 31/146 (21%), Positives = 62/146 (42%), Gaps = 9/146 (6%) Frame = +2 Query: 95 VKVWNLTNCKLRCTLD-----GHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL---TEGK 250 VK+W+++ + + Y+ + + PDG GG+ +WDL T Sbjct: 509 VKIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPDGRTLIVGGEASTLTIWDLASPTPRI 568 Query: 251 RLYSLDAGSIINSLCFSPN-RYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYC 427 + + +L SP+ + + +I +WDL ++ +V+ + +S Sbjct: 569 KAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGAS------ 622 Query: 428 TCLSWSADGSTLYAGYTDGTIRIYKI 505 C+ S DG+ L+ G D T+R + + Sbjct: 623 -CIDISHDGTKLWTGGLDNTVRSWDL 647 Score = 37.4 bits (85), Expect = 0.029 Identities = 29/135 (21%), Positives = 56/135 (41%), Gaps = 5/135 (3%) Frame = +2 Query: 65 TIVSGSWDRSVKVWNLTNC--KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL 238 T++ G ++ +W+L + +++ L A+A+SPD +C S DG +WDL Sbjct: 546 TLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDL 605 Query: 239 ---TEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSS 409 T ++ G+ + + W ++++ WDL +Q + + Sbjct: 606 HNQTLVRQFQGHTDGASCIDISHDGTKLW-TGGLDNTVRSWDLREGRQLQ--QHDFTSQI 662 Query: 410 KQMLYCTCLSWSADG 454 + YC W A G Sbjct: 663 FSLGYCPTGEWLAVG 677
>YNA6_YEAST (P41318) Hypothetical 34.0 kDa Trp-Asp repeats-containing protein| in SIS1-MRPL2 intergenic region Length = 303 Score = 54.7 bits (130), Expect = 2e-07 Identities = 37/149 (24%), Positives = 71/149 (47%), Gaps = 3/149 (2%) Frame = +2 Query: 89 RSVKVWNL--TNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYS 262 ++V+++++ TN + +GH G V++V+ D + +DG +WD+ + Sbjct: 53 QNVRLYDIRTTNPNPVASFEGHRGNVTSVSFQQDNRWMVTSSEDGTIKVWDVRSPSIPRN 112 Query: 263 LDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLS 439 + +N + PN+ L + +D +I+IWDL L PE S + LS Sbjct: 113 YKHNAPVNEVVIHPNQGELISCDRDGNIRIWDLGENQCTHQLTPEDDTSLQS------LS 166 Query: 440 WSADGSTLYAGYTDGTIRIYKISGFSYSS 526 ++DGS L A T G ++++ + +S Sbjct: 167 MASDGSMLAAANTKGNCYVWEMPNHTDAS 195 Score = 37.7 bits (86), Expect = 0.022 Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 1/55 (1%) Frame = +2 Query: 80 SWDRSVKVWNLTN-CKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLT 241 S D + +VW++ + KL TLDGH +V A S D + + D LWDL+ Sbjct: 226 SADHTARVWSIDDDFKLETTLDGHQRWVWDCAFSADSAYLVTASSDHYVRLWDLS 280
>TLE3_MOUSE (Q08122) Transducin-like enhancer protein 3 (ESG) (Grg-3)| Length = 771 Score = 54.7 bits (130), Expect = 2e-07 Identities = 30/85 (35%), Positives = 41/85 (48%) Frame = +2 Query: 86 DRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSL 265 D ++ VW+L N L GH S + +S DG+ +GG D WDL EG++L Sbjct: 596 DGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQH 655 Query: 266 DAGSIINSLCFSPNRYWLCAATQDS 340 D S I SL + P WL + S Sbjct: 656 DFTSQIFSLGYCPTGEWLAVGMESS 680 Score = 44.7 bits (104), Expect = 2e-04 Identities = 31/146 (21%), Positives = 62/146 (42%), Gaps = 9/146 (6%) Frame = +2 Query: 95 VKVWNLTNCKLRCTLD-----GHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL---TEGK 250 VK+W+++ + + Y+ + + PDG GG+ +WDL T Sbjct: 508 VKIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPDGRTLIVGGEASTLTIWDLASPTPRI 567 Query: 251 RLYSLDAGSIINSLCFSPN-RYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYC 427 + + +L SP+ + + +I +WDL ++ +V+ + +S Sbjct: 568 KAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGAS------ 621 Query: 428 TCLSWSADGSTLYAGYTDGTIRIYKI 505 C+ S DG+ L+ G D T+R + + Sbjct: 622 -CIDISHDGTKLWTGGLDNTVRSWDL 646 Score = 37.4 bits (85), Expect = 0.029 Identities = 29/135 (21%), Positives = 56/135 (41%), Gaps = 5/135 (3%) Frame = +2 Query: 65 TIVSGSWDRSVKVWNLTNC--KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL 238 T++ G ++ +W+L + +++ L A+A+SPD +C S DG +WDL Sbjct: 545 TLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDL 604 Query: 239 ---TEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSS 409 T ++ G+ + + W ++++ WDL +Q + + Sbjct: 605 HNQTLVRQFQGHTDGASCIDISHDGTKLW-TGGLDNTVRSWDLREGRQLQ--QHDFTSQI 661 Query: 410 KQMLYCTCLSWSADG 454 + YC W A G Sbjct: 662 FSLGYCPTGEWLAVG 676
>WDR1_DROME (Q9VU68) Putative actin-interacting protein 1 (AIP1)| Length = 608 Score = 54.7 bits (130), Expect = 2e-07 Identities = 38/132 (28%), Positives = 64/132 (48%), Gaps = 4/132 (3%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 IV+GS D ++ V+ K + T H +V AV SPDG AS G DG L+D T Sbjct: 168 IVTGSEDNTIAVFEGPPFKFKMTKQDHSRFVQAVRYSPDGKFFASAGFDGKVFLYDGTSS 227 Query: 248 KRLYSLDAGSI---INSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQDLRPEVPVSSKQ 415 + + + + + +L + P+ L + D + ++W +ES+ +V + V +Q Sbjct: 228 ELVGEFGSPAHKGGVYALAWKPDSTQLLTCSGDKTCRLWTVESRELVSEFVMGTTVDDQQ 287 Query: 416 MLYCTCLSWSAD 451 + +CL W D Sbjct: 288 V---SCL-WQGD 295 Score = 31.2 bits (69), Expect = 2.1 Identities = 19/76 (25%), Positives = 33/76 (43%), Gaps = 3/76 (3%) Frame = +2 Query: 146 HGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKR---LYSLDAGSIINSLCFSPNRYW 316 H V+ VA SP+ L ASG D ++W + + + + S I L + N Sbjct: 532 HSARVNTVAWSPNSLLVASGSLDTTIIIWSVANPAKHTIIKNAHPQSQITRLVWLDNNTV 591 Query: 317 LCAATQDSIKIWDLES 364 + + K+W +E+ Sbjct: 592 ISTGQDCNTKVWHVEN 607
>TLE2_XENLA (O42478) Enhancer of split groucho-like protein 2 (Fragment)| Length = 198 Score = 54.7 bits (130), Expect = 2e-07 Identities = 30/85 (35%), Positives = 41/85 (48%) Frame = +2 Query: 86 DRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSL 265 D ++ VW+L N L GH S + +S DG+ +GG D WDL EG++L Sbjct: 23 DGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQH 82 Query: 266 DAGSIINSLCFSPNRYWLCAATQDS 340 D S I SL + P WL + S Sbjct: 83 DFTSQIFSLGYCPTGEWLAVGMESS 107 Score = 31.6 bits (70), Expect = 1.6 Identities = 24/100 (24%), Positives = 41/100 (41%), Gaps = 3/100 (3%) Frame = +2 Query: 164 AVAVSPDGSLCASGGKDGVTLLWDL---TEGKRLYSLDAGSIINSLCFSPNRYWLCAATQ 334 A+A+SPD +C S DG +WDL T ++ G+ + + W Sbjct: 7 ALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLW-TGGLD 65 Query: 335 DSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADG 454 ++++ WDL +Q + + + YC W A G Sbjct: 66 NTVRSWDLREGRQLQ--QHDFTSQIFSLGYCPTGEWLAVG 103 Score = 31.6 bits (70), Expect = 1.6 Identities = 18/74 (24%), Positives = 36/74 (48%), Gaps = 1/74 (1%) Frame = +2 Query: 287 SLCFSPN-RYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTL 463 +L SP+ + + +I +WDL ++ +V+ + +S C+ S DG+ L Sbjct: 7 ALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGAS-------CIDISNDGTKL 59 Query: 464 YAGYTDGTIRIYKI 505 + G D T+R + + Sbjct: 60 WTGGLDNTVRSWDL 73
>UTP15_PONPY (Q5REE0) U3 small nucleolar RNA-associated protein 15 homolog| Length = 518 Score = 54.7 bits (130), Expect = 2e-07 Identities = 49/189 (25%), Positives = 86/189 (45%), Gaps = 10/189 (5%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVS---AVAVSP 181 G T V V F+ + + +VSG+ D +VK+W++ N K T H YV A ++P Sbjct: 120 GHTKAVHTVDFTADKYH--VVSGADDYTVKLWDIPNSKEVLTFKEHSDYVRCGCASKLNP 177 Query: 182 DGSLCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWD-L 358 D L +G D ++D + + S++ G + S+ P+ L +A +K+ D L Sbjct: 178 D--LFITGSYDHTVKMFDARTSESVLSVEHGQPVESVLLFPSGGLLVSAGGRYVKVCDML 235 Query: 359 ESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYK------ISGFSY 520 + ++ L+ TCL S+ G L +G D +++Y + F Y Sbjct: 236 KGGQLLVSLKNHHKT-------VTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSFDY 288 Query: 521 SS*IMYLVL 547 ++ I+ L L Sbjct: 289 AASILSLAL 297
>SEL10_CAEEL (Q93794) F-box/WD-repeat protein sel-10 (Suppressor/enhancer of| lin-12) (Sel-10 protein) Length = 587 Score = 54.7 bits (130), Expect = 2e-07 Identities = 48/174 (27%), Positives = 83/174 (47%), Gaps = 6/174 (3%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG 187 +G T V C+ + + +V+GS D +++VW++ + + TL GH V V DG Sbjct: 335 QGHTSTVRCMAMAGS----ILVTGSRDTTLRVWDVESGRHLATLHGHHAAVRCVQF--DG 388 Query: 188 SLCASGGKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQD-SIKIWDL- 358 + SGG D +W+ G+ + +L + + SL F R +C+ + D SI++WD Sbjct: 389 TTVVSGGYDFTVKIWNAHTGRCIRTLTGHNNRVYSLLFESERSIVCSGSLDTSIRVWDFT 448 Query: 359 --ESKHIVQDLRPEVPVSSKQMLYCTCL-SWSADGSTLYAGYTDGTIRIYKISG 511 E + V L+ ++S L L S +AD +GT ++ +SG Sbjct: 449 RPEGQECVALLQGHTSLTSGMQLRGNILVSCNADSHVRVWDIHEGTC-VHMLSG 501 Score = 54.3 bits (129), Expect = 2e-07 Identities = 45/164 (27%), Positives = 71/164 (43%), Gaps = 4/164 (2%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 V CV+F T+VSG +D +VK+WN + TL GH V ++ + S+ SG Sbjct: 381 VRCVQFD----GTTVVSGGYDFTVKIWNAHTGRCIRTLTGHNNRVYSLLFESERSIVCSG 436 Query: 206 GKDGVTLLWDLT--EGKRLYSLDAG--SIINSLCFSPNRYWLCAATQDSIKIWDLESKHI 373 D +WD T EG+ +L G S+ + + N C A +++WD+ Sbjct: 437 SLDTSIRVWDFTRPEGQECVALLQGHTSLTSGMQLRGNILVSCNA-DSHVRVWDIHEGTC 495 Query: 374 VQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 V L S T L W + + DGT++++ I Sbjct: 496 VHML-------SGHRSAITSLQWFG-RNMVATSSDDGTVKLWDI 531 Score = 53.9 bits (128), Expect = 3e-07 Identities = 40/146 (27%), Positives = 68/146 (46%), Gaps = 2/146 (1%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 +V+GS D ++KVW + ++ TL GH G V +S G SG D +W +G Sbjct: 269 LVTGSDDNTLKVWCIDKGEVMYTLVGHTGGVWTSQISQCGRYIVSGSTDRTVKVWSTVDG 328 Query: 248 KRLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLES-KHIVQDLRPEVPVSSKQML 421 L++L G C + L ++D ++++WD+ES +H+ V Q Sbjct: 329 SLLHTLQ-GHTSTVRCMAMAGSILVTGSRDTTLRVWDVESGRHLATLHGHHAAVRCVQF- 386 Query: 422 YCTCLSWSADGSTLYAGYTDGTIRIY 499 DG+T+ +G D T++I+ Sbjct: 387 ---------DGTTVVSGGYDFTVKIW 403 Score = 47.0 bits (110), Expect = 4e-05 Identities = 30/110 (27%), Positives = 54/110 (49%), Gaps = 4/110 (3%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLR---CTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL 238 + SGS D S++VW+ T + + L GH S + + G++ S D +WD+ Sbjct: 433 VCSGSLDTSIRVWDFTRPEGQECVALLQGHTSLTSGMQLR--GNILVSCNADSHVRVWDI 490 Query: 239 TEGKRLYSLDAG-SIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDL 385 EG ++ L S I SL + ++ ++K+WD+E +++DL Sbjct: 491 HEGTCVHMLSGHRSAITSLQWFGRNMVATSSDDGTVKLWDIERGALIRDL 540
>TLE3_RAT (Q9JIT3) Transducin-like enhancer protein 3 (rTLE3)| Length = 764 Score = 54.7 bits (130), Expect = 2e-07 Identities = 30/85 (35%), Positives = 41/85 (48%) Frame = +2 Query: 86 DRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSL 265 D ++ VW+L N L GH S + +S DG+ +GG D WDL EG++L Sbjct: 589 DGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQH 648 Query: 266 DAGSIINSLCFSPNRYWLCAATQDS 340 D S I SL + P WL + S Sbjct: 649 DFTSQIFSLGYCPTGEWLAVGMESS 673 Score = 44.7 bits (104), Expect = 2e-04 Identities = 31/146 (21%), Positives = 62/146 (42%), Gaps = 9/146 (6%) Frame = +2 Query: 95 VKVWNLTNCKLRCTLD-----GHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL---TEGK 250 VK+W+++ + + Y+ + + PDG GG+ +WDL T Sbjct: 501 VKIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPDGRTLIVGGEASTLTIWDLASPTPRI 560 Query: 251 RLYSLDAGSIINSLCFSPN-RYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYC 427 + + +L SP+ + + +I +WDL ++ +V+ + +S Sbjct: 561 KAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGAS------ 614 Query: 428 TCLSWSADGSTLYAGYTDGTIRIYKI 505 C+ S DG+ L+ G D T+R + + Sbjct: 615 -CIDISHDGTKLWTGGLDNTVRSWDL 639 Score = 37.4 bits (85), Expect = 0.029 Identities = 29/135 (21%), Positives = 56/135 (41%), Gaps = 5/135 (3%) Frame = +2 Query: 65 TIVSGSWDRSVKVWNLTNC--KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL 238 T++ G ++ +W+L + +++ L A+A+SPD +C S DG +WDL Sbjct: 538 TLIVGGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDL 597 Query: 239 ---TEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSS 409 T ++ G+ + + W ++++ WDL +Q + + Sbjct: 598 HNQTLVRQFQGHTDGASCIDISHDGTKLW-TGGLDNTVRSWDLREGRQLQ--QHDFTSQI 654 Query: 410 KQMLYCTCLSWSADG 454 + YC W A G Sbjct: 655 FSLGYCPTGEWLAVG 669
>CAF1_DROME (Q24572) Probable histone-binding protein Caf1 (Chromatin assembly| factor 1 p55 subunit) (CAF-1 p55 subunit) (dCAF-1) (Nucleosome remodeling factor 55 kDa subunit) (NURF-55) Length = 430 Score = 54.7 bits (130), Expect = 2e-07 Identities = 41/149 (27%), Positives = 79/149 (53%), Gaps = 19/149 (12%) Frame = +2 Query: 17 TGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRC-TLDGHGGYVSAVAVSPDG-S 190 T V+C+ F+P + + +GS D++V +W+L N KL+ + + H + V SP + Sbjct: 277 TAEVNCLSFNPYSEF-ILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNET 335 Query: 191 LCASGGKDGVTLLWDLTE-GKRLYSLDAG--------------SIINSLCFSPNRYWL-C 322 + AS G D +WDL++ G+ + DA + I+ ++PN W+ C Sbjct: 336 ILASSGTDRRLHVWDLSKIGEEQSTEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWIIC 395 Query: 323 AATQDSI-KIWDLESKHIVQDLRPEVPVS 406 + ++D+I ++W + ++++ D PE+P S Sbjct: 396 SVSEDNIMQVWQM-AENVYNDEEPEIPAS 423
>FBW1B_HUMAN (Q9UKB1) F-box/WD-repeat protein 11 (F-box/WD-repeat protein 1B)| (F-box and WD-repeats protein beta-TrCP2) Length = 542 Score = 54.3 bits (129), Expect = 2e-07 Identities = 35/114 (30%), Positives = 53/114 (46%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 IVS S DR++KVW+ + C+ TL+GH ++ + L SG D LWD+ G Sbjct: 376 IVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYR--DRLVVSGSSDNTIRLWDIECG 433 Query: 248 KRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSS 409 L L+ + N+ + A IK+WDL++ L P P S+ Sbjct: 434 ACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAA-----LDPRAPAST 482 Score = 47.4 bits (111), Expect = 3e-05 Identities = 30/100 (30%), Positives = 49/100 (49%), Gaps = 1/100 (1%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 I+SG D S+K+W+ T+ + L GH G S + + D + +G D +WD+ G Sbjct: 253 IISGLRDNSIKIWDKTSLECLKVLTGHTG--SVLCLQYDERVIVTGSSDSTVRVWDVNTG 310 Query: 248 KRLYSL-DAGSIINSLCFSPNRYWLCAATQDSIKIWDLES 364 + L +L + L FS N + + SI +WD+ S Sbjct: 311 EVLNTLIHHNEAVLHLRFS-NGLMVTCSKDRSIAVWDMAS 349
>FBW1A_HUMAN (Q9Y297) F-box/WD-repeat protein 1A (F-box and WD-repeats protein| beta-TrCP) (E3RSIkappaB) (pIkappaBalpha-E3 receptor subunit) Length = 605 Score = 54.3 bits (129), Expect = 2e-07 Identities = 36/114 (31%), Positives = 51/114 (44%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 IVS S DR++KVWN + C+ TL+GH ++ + L SG D LWD+ G Sbjct: 439 IVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYR--DRLVVSGSSDNTIRLWDIECG 496 Query: 248 KRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSS 409 L L+ + N+ + A IK+WDL V L P P + Sbjct: 497 ACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDL-----VAALDPRAPAGT 545 Score = 43.9 bits (102), Expect = 3e-04 Identities = 28/100 (28%), Positives = 48/100 (48%), Gaps = 1/100 (1%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 IVSG D ++K+W+ + + L GH G S + + D + +G D +WD+ G Sbjct: 316 IVSGLRDNTIKIWDKNTLECKRILTGHTG--SVLCLQYDERVIITGSSDSTVRVWDVNTG 373 Query: 248 KRLYSL-DAGSIINSLCFSPNRYWLCAATQDSIKIWDLES 364 + L +L + L F+ C+ + SI +WD+ S Sbjct: 374 EMLNTLIHHCEAVLHLRFNNGMMVTCSKDR-SIAVWDMAS 412
>TRCB_XENLA (Q91854) Beta-TrCP (Beta-transducin repeat-containing protein)| Length = 518 Score = 54.3 bits (129), Expect = 2e-07 Identities = 36/114 (31%), Positives = 51/114 (44%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 IVS S DR++KVWN + C+ TL+GH ++ + L SG D LWD+ G Sbjct: 368 IVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYR--DRLVVSGSSDNTIRLWDIECG 425 Query: 248 KRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSS 409 L L+ + N+ + A IK+WDL V L P P + Sbjct: 426 ACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDL-----VAALDPRAPAGT 474 Score = 43.5 bits (101), Expect = 4e-04 Identities = 28/100 (28%), Positives = 48/100 (48%), Gaps = 1/100 (1%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 IVSG D ++K+W+ + + L GH G S + + D + +G D +WD+ G Sbjct: 245 IVSGLRDNTIKIWDKNTLECKRVLMGHTG--SVLCLQYDERVIITGSSDSTVRVWDVNTG 302 Query: 248 KRLYSL-DAGSIINSLCFSPNRYWLCAATQDSIKIWDLES 364 + L +L + L F+ C+ + SI +WD+ S Sbjct: 303 EMLNTLIHHCEAVLHLRFNNGMMVTCSKDR-SIAVWDMAS 341
>PRP46_CRYNE (Q5KDR4) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 473 Score = 54.3 bits (129), Expect = 2e-07 Identities = 35/121 (28%), Positives = 57/121 (47%), Gaps = 2/121 (1%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G GWV V P N +G+ DR +K+W+L + +L+ +L GH + +AVS Sbjct: 180 GHMGWVRAVAMDPGN--QWFATGAGDRVIKIWDLASGELKLSLTGHISTIRGLAVSDRHP 237 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAG-SIINSLCFSPNRYWLCAATQD-SIKIWDLES 364 S +D + WDL K + S + SL P L +D S+++WD+ + Sbjct: 238 YLFSCAEDKMVKCWDLETNKVIRHYHGHFSGVYSLSVHPTLDVLVTGGRDASVRVWDMRT 297 Query: 365 K 367 + Sbjct: 298 R 298 Score = 53.9 bits (128), Expect = 3e-07 Identities = 42/149 (28%), Positives = 67/149 (44%), Gaps = 3/149 (2%) Frame = +2 Query: 62 PTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTL-LWDL 238 P I+SGS D +V++W+L K TL H V A+A+ P AS G + W Sbjct: 321 PQIISGSMDSTVRLWDLAAGKCMNTLTHHKKSVRALAIHPTEYSFASASSGGNNIKKWKC 380 Query: 239 TEGKRLYS-LDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRP-EVPVSSK 412 EG + + + +IIN+L + A ++ +WD ++ Q L+ P S Sbjct: 381 PEGIFVNNFVGHEAIINTLSINSENVLFSGADNGTLTLWDYKTGLPFQHLKDIPQPGSLD 440 Query: 413 QMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 C ++ G+ L G D TI++Y Sbjct: 441 AEAGVFCSTFDKTGTRLITGGADKTIKVY 469 Score = 53.9 bits (128), Expect = 3e-07 Identities = 34/99 (34%), Positives = 48/99 (48%), Gaps = 2/99 (2%) Frame = +2 Query: 89 RSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLD 268 R VK KL + GH G+V AVA+ P A+G D V +WDL G+ SL Sbjct: 162 REVKPEYHPEWKLTRVISGHMGWVRAVAMDPGNQWFATGAGDRVIKIWDLASGELKLSLT 221 Query: 269 AG-SIINSLCFSPNRYWLCAATQDS-IKIWDLESKHIVQ 379 S I L S +L + +D +K WDLE+ +++ Sbjct: 222 GHISTIRGLAVSDRHPYLFSCAEDKMVKCWDLETNKVIR 260 Score = 45.8 bits (107), Expect = 8e-05 Identities = 30/98 (30%), Positives = 43/98 (43%), Gaps = 3/98 (3%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 +V+G D SV+VW++ TL GH V V SG D LWDL G Sbjct: 281 LVTGGRDASVRVWDMRTRANIFTLTGHTSTVGDVKTQDSDPQIISGSMDSTVRLWDLAAG 340 Query: 248 KRLYSL-DAGSIINSLCFSPNRYWLCAATQ--DSIKIW 352 K + +L + +L P Y +A+ ++IK W Sbjct: 341 KCMNTLTHHKKSVRALAIHPTEYSFASASSGGNNIKKW 378 Score = 44.7 bits (104), Expect = 2e-04 Identities = 29/117 (24%), Positives = 59/117 (50%), Gaps = 3/117 (2%) Frame = +2 Query: 17 TGWVSCVR-FSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSL 193 TG +S +R + ++ P + S + D+ VK W+L K+ GH V +++V P + Sbjct: 221 TGHISTIRGLAVSDRHPYLFSCAEDKMVKCWDLETNKVIRHYHGHFSGVYSLSVHPTLDV 280 Query: 194 CASGGKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQDS-IKIWDL 358 +GG+D +WD+ +++L S + + + + + + DS +++WDL Sbjct: 281 LVTGGRDASVRVWDMRTRANIFTLTGHTSTVGDVKTQDSDPQIISGSMDSTVRLWDL 337
>GBB1_TOBAC (P93397) Guanine nucleotide-binding protein beta subunit 1| Length = 377 Score = 54.3 bits (129), Expect = 2e-07 Identities = 51/175 (29%), Positives = 78/175 (44%), Gaps = 8/175 (4%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNL-TNCKLRCTLDGHGGYVSAVAVSPDG 187 G T V V S +N VSGS D + ++W+ + + T GH G V+ V PDG Sbjct: 202 GHTADVQSVSISSSN-PRLFVSGSCDTTARLWDTRVASRAQRTFYGHEGDVNTVKFFPDG 260 Query: 188 SLCASGGKDGVTLLWDL-TEGK-RLYSLDAGS----IINSLCFS-PNRYWLCAATQDSIK 346 + +G +DG L+D+ TE + ++Y G + S+ FS R + Sbjct: 261 NRFGTGSEDGTCRLFDIRTEHQLQVYYQPHGDGDIPHVTSMAFSISGRLLFVGYSNGDCY 320 Query: 347 IWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISG 511 +WD +V +L V + +CL SADGS L G D ++I+ G Sbjct: 321 VWDTLLAKVVLNLG---GVQNSHEGRISCLGLSADGSALCTGSWDTNLKIWAFGG 372 Score = 47.0 bits (110), Expect = 4e-05 Identities = 47/188 (25%), Positives = 74/188 (39%), Gaps = 24/188 (12%) Frame = +2 Query: 14 PTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLT-------NCKLRCTLDGHGGYVSAVA 172 P WV FSP+ ++ G D ++NL N + L GH GYVS+ Sbjct: 106 PCAWVMTCAFSPSG--QSVACGGLDSVCSIFNLNSPIDKDGNHPVSRMLSGHKGYVSSCQ 163 Query: 173 VSPDGS--LCASGGKDGVTLLWDLTEGKRL----------YSLDAGSIINSLCFSPNRYW 316 PD L S G D +LWD+T G R ++ D S+ S+ S R + Sbjct: 164 YVPDEDTHLITSSG-DQTCVLWDITTGLRTSVFGGEFQSGHTADVQSV--SISSSNPRLF 220 Query: 317 LCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLY-----CTCLSWSADGSTLYAGYTD 481 + + + ++WD V +++ Y + + DG+ G D Sbjct: 221 VSGSCDTTARLWD-----------TRVASRAQRTFYGHEGDVNTVKFFPDGNRFGTGSED 269 Query: 482 GTIRIYKI 505 GT R++ I Sbjct: 270 GTCRLFDI 277 Score = 29.6 bits (65), Expect = 6.1 Identities = 20/88 (22%), Positives = 45/88 (51%), Gaps = 2/88 (2%) Frame = +2 Query: 107 NLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLDAG-SII 283 +L C++ L GH G V ++ +P+ + S +DG ++W+ ++ +++ + + Sbjct: 54 DLVCCRI---LQGHTGKVYSLDWTPEKNRIVSASQDGRLIVWNALTSQKTHAIKLPCAWV 110 Query: 284 NSLCFSPNRYWLCAATQDSI-KIWDLES 364 + FSP+ + DS+ I++L S Sbjct: 111 MTCAFSPSGQSVACGGLDSVCSIFNLNS 138
>TLE2_MOUSE (Q9WVB2) Transducin-like enhancer protein 2| Length = 767 Score = 53.9 bits (128), Expect = 3e-07 Identities = 32/104 (30%), Positives = 47/104 (45%) Frame = +2 Query: 29 SCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGG 208 +C + + A S D ++ VW+L N + GH S + +S G+ +GG Sbjct: 573 ACYALAVSPDAKVCFSCCSDGNIVVWDLQNQAMVRQFQGHTDGASCIDISDYGTRLWTGG 632 Query: 209 KDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDS 340 D WDL EG++L D S I SL PN+ WL + S Sbjct: 633 LDNTVRCWDLREGRQLQQHDFSSQIFSLGHCPNQDWLAVGMESS 676 Score = 40.0 bits (92), Expect = 0.004 Identities = 33/148 (22%), Positives = 62/148 (41%), Gaps = 11/148 (7%) Frame = +2 Query: 95 VKVWNLTN-------CKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL---TE 244 VKVW++ +L C Y+ + + PDG GG+ +WDL T Sbjct: 504 VKVWDVGQPGSKTPVAQLDCL--NRDNYIRSCKLLPDGQSLIVGGEASTLSIWDLAAPTP 561 Query: 245 GKRLYSLDAGSIINSLCFSPN-RYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQML 421 + + +L SP+ + + +I +WDL+++ +V+ + +S Sbjct: 562 RIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQAMVRQFQGHTDGAS---- 617 Query: 422 YCTCLSWSADGSTLYAGYTDGTIRIYKI 505 C+ S G+ L+ G D T+R + + Sbjct: 618 ---CIDISDYGTRLWTGGLDNTVRCWDL 642
>TLE1_BRARE (O13168) Groucho 1 protein (Fragment)| Length = 535 Score = 53.9 bits (128), Expect = 3e-07 Identities = 30/85 (35%), Positives = 40/85 (47%) Frame = +2 Query: 86 DRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSL 265 D ++ VW+L N L GH S + +S DG +GG D WDL EG++L Sbjct: 360 DGNIAVWDLHNQTLVRQFQGHTDGASCIDISHDGPKLWTGGLDNTVRSWDLREGRQLQQH 419 Query: 266 DAGSIINSLCFSPNRYWLCAATQDS 340 D S I SL + P WL + S Sbjct: 420 DFTSQIFSLGYCPTGEWLAVGMESS 444 Score = 44.7 bits (104), Expect = 2e-04 Identities = 33/148 (22%), Positives = 63/148 (42%), Gaps = 11/148 (7%) Frame = +2 Query: 95 VKVWNLTN-------CKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL---TE 244 VK+W+++ +L C Y+ + + PDG +GG+ +WDL T Sbjct: 272 VKIWDISQPGSKSPVSQLDCL--NRDNYIRSCKLLPDGRTLIAGGEVSTLTIWDLASQTP 329 Query: 245 GKRLYSLDAGSIINSLCFSPN-RYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQML 421 + + +L SP+ + + +I +WDL ++ +V+ + +S Sbjct: 330 RIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGAS---- 385 Query: 422 YCTCLSWSADGSTLYAGYTDGTIRIYKI 505 C+ S DG L+ G D T+R + + Sbjct: 386 ---CIDISHDGPKLWTGGLDNTVRSWDL 410 Score = 37.4 bits (85), Expect = 0.029 Identities = 29/135 (21%), Positives = 57/135 (42%), Gaps = 5/135 (3%) Frame = +2 Query: 65 TIVSGSWDRSVKVWNLTNC--KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL 238 T+++G ++ +W+L + +++ L A+A+SPD +C S DG +WDL Sbjct: 309 TLIAGGEVSTLTIWDLASQTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDL 368 Query: 239 ---TEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSS 409 T ++ G+ + + W ++++ WDL +Q + + Sbjct: 369 HNQTLVRQFQGHTDGASCIDISHDGPKLW-TGGLDNTVRSWDLREGRQLQ--QHDFTSQI 425 Query: 410 KQMLYCTCLSWSADG 454 + YC W A G Sbjct: 426 FSLGYCPTGEWLAVG 440
>FBXW7_MOUSE (Q8VBV4) F-box/WD-repeat protein 7 (F-box and WD-40 domain protein| 7) (F-box protein FBW7) (F-box protein Fbxw6) (F-box-WD40 repeat protein 6) (SEL-10) Length = 629 Score = 53.9 bits (128), Expect = 3e-07 Identities = 41/165 (24%), Positives = 73/165 (44%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G V CV++ +VSG++D VKVW+ TL GH V ++ DG Sbjct: 421 GHVAAVRCVQYDGRR----VVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGI 474 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKH 370 SG D +WD+ G +++L + S + + ++KIWD+++ Sbjct: 475 HVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQ 534 Query: 371 IVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 +Q L+ SK TCL ++ + + DGT++++ + Sbjct: 535 CLQTLQG----PSKHQSAVTCLQFNK--NFVITSSDDGTVKLWDL 573 Score = 48.9 bits (115), Expect = 1e-05 Identities = 40/147 (27%), Positives = 66/147 (44%), Gaps = 1/147 (0%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 I+SGS DR++KVWN + TL GH V + + SG +D +WD+ G Sbjct: 356 IISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETG 413 Query: 248 KRLYSLDAGSIINSLCFS-PNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLY 424 + L+ L G + C R + A +K+WD E++ + L+ +Y Sbjct: 414 QCLHVL-MGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQ-----GHTNRVY 467 Query: 425 CTCLSWSADGSTLYAGYTDGTIRIYKI 505 S DG + +G D +IR++ + Sbjct: 468 ----SLQFDGIHVVSGSLDTSIRVWDV 490 Score = 46.6 bits (109), Expect = 5e-05 Identities = 38/159 (23%), Positives = 75/159 (47%), Gaps = 1/159 (0%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 ++C++F N IVSGS D ++KVW+ K TL GH G V + + ++ SG Sbjct: 306 ITCLQFCGNR----IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMR--DNIIISG 359 Query: 206 GKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQD 382 D +W+ G+ +++L G C + + + ++D ++++WD+E+ + Sbjct: 360 STDRTLKVWNAETGECIHTL-YGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHV 418 Query: 383 LRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 L V C+ + DG + +G D ++++ Sbjct: 419 LMGHVAA-------VRCVQY--DGRRVVSGAYDFMVKVW 448 Score = 38.1 bits (87), Expect = 0.017 Identities = 23/73 (31%), Positives = 39/73 (53%), Gaps = 4/73 (5%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVA-VSPDGSLCASGGKDGVTLLWDLTE 244 +VSG+ D +VK+W++ + TL G + SAV + + + + DG LWDL Sbjct: 516 LVSGNADSTVKIWDIKTGQCLQTLQGPSKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKT 575 Query: 245 G---KRLYSLDAG 274 G + L +L++G Sbjct: 576 GEFIRNLVTLESG 588
>TLE2_HUMAN (Q04725) Transducin-like enhancer protein 2 (ESG2)| Length = 743 Score = 53.9 bits (128), Expect = 3e-07 Identities = 32/104 (30%), Positives = 47/104 (45%) Frame = +2 Query: 29 SCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGG 208 +C + + A S D ++ VW+L N + GH S + +S G+ +GG Sbjct: 549 ACYALAVSPDAKVCFSCCSDGNIVVWDLQNQTMVRQFQGHTDGASCIDISDYGTRLWTGG 608 Query: 209 KDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDS 340 D WDL EG++L D S I SL PN+ WL + S Sbjct: 609 LDNTVRCWDLREGRQLQQHDFSSQIFSLGHCPNQDWLAVGMESS 652 Score = 39.7 bits (91), Expect = 0.006 Identities = 33/148 (22%), Positives = 62/148 (41%), Gaps = 11/148 (7%) Frame = +2 Query: 95 VKVWNLTN-------CKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL---TE 244 VKVW++ +L C Y+ + + PDG GG+ +WDL T Sbjct: 480 VKVWDVGQPGAKTPVAQLDCL--NRDNYIRSCKLLPDGRSLIVGGEASTLSIWDLAAPTP 537 Query: 245 GKRLYSLDAGSIINSLCFSPN-RYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQML 421 + + +L SP+ + + +I +WDL+++ +V+ + +S Sbjct: 538 RIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQTMVRQFQGHTDGAS---- 593 Query: 422 YCTCLSWSADGSTLYAGYTDGTIRIYKI 505 C+ S G+ L+ G D T+R + + Sbjct: 594 ---CIDISDYGTRLWTGGLDNTVRCWDL 618
>GBB2_DROME (P29829) Guanine nucleotide-binding protein beta subunit 2| Length = 346 Score = 53.9 bits (128), Expect = 3e-07 Identities = 37/162 (22%), Positives = 74/162 (45%), Gaps = 2/162 (1%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G G++S RF + +++GS D + W+L +GH G ++ +++SPD Sbjct: 147 GYEGFLSSCRFLDDGH---LITGSGDMKICHWDLEKGVKTMDFNGHAGDIAGLSLSPDMK 203 Query: 191 LCASGGKDGVTLLWDL-TEGKRLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLES 364 +G D LWD+ EG + ++S+C+ P+ + + ++D + +++DL + Sbjct: 204 TYITGSVDKTAKLWDVREEGHKQMFFGHDMDVSSVCYHPSGFGFASCSEDQTARMYDLRA 263 Query: 365 KHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTI 490 + P K + +C + S G L G +G + Sbjct: 264 DQQIAQYEP----PQKNTGFTSC-ALSTSGRYLMCGGIEGNV 300 Score = 34.7 bits (78), Expect = 0.19 Identities = 18/79 (22%), Positives = 38/79 (48%), Gaps = 2/79 (2%) Frame = +2 Query: 137 LDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLDAGSI-INSLCFSPN-R 310 L GH V++V + D C +G DG ++WD ++ + S + ++ FSP+ Sbjct: 55 LKGHINKVNSVHFAGDSRHCVTGSLDGKLIIWDTWTANKVQIIPLRSAWVMTVAFSPSGN 114 Query: 311 YWLCAATQDSIKIWDLESK 367 + C + ++D+ ++ Sbjct: 115 FVACGGMDNQCTVYDVNNR 133 Score = 33.5 bits (75), Expect = 0.42 Identities = 18/72 (25%), Positives = 33/72 (45%) Frame = +2 Query: 17 TGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLC 196 TG+ SC + + ++ G + +V W+ + TL GH ++ +++ P+G Sbjct: 277 TGFTSCALSTSGRY---LMCGGIEGNVHSWDTMKQRHTGTLSGHENRITCISLCPNGMCL 333 Query: 197 ASGGKDGVTLLW 232 AS D LW Sbjct: 334 ASTSWDQQVRLW 345 Score = 33.5 bits (75), Expect = 0.42 Identities = 34/154 (22%), Positives = 56/154 (36%), Gaps = 9/154 (5%) Frame = +2 Query: 71 VSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG- 247 V+GS D + +W+ + +V VA SP G+ A GG D ++D+ Sbjct: 75 VTGSLDGKLIIWDTWTANKVQIIPLRSAWVMTVAFSPSGNFVACGGMDNQCTVYDVNNRD 134 Query: 248 --------KRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPV 403 K L + ++S F + + + + I WDLE D Sbjct: 135 ASGVAKMVKELMGYE--GFLSSCRFLDDGHLITGSGDMKICHWDLEKGVKTMDFNGHAGD 192 Query: 404 SSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 + LS S D T G D T +++ + Sbjct: 193 IAG-------LSLSPDMKTYITGSVDKTAKLWDV 219
>RBBP7_XENTR (Q6P315) Histone-binding protein RBBP7 (Retinoblastoma-binding| protein 7) (RBBP-7) Length = 425 Score = 53.9 bits (128), Expect = 3e-07 Identities = 42/149 (28%), Positives = 79/149 (53%), Gaps = 19/149 (12%) Frame = +2 Query: 17 TGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRC-TLDGHGGYVSAVAVSPDG-S 190 T V+C+ F+P + + +GS D++V +W+L N KL+ + + H + V SP + Sbjct: 272 TAEVNCLSFNPYSEF-ILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVHWSPHNET 330 Query: 191 LCASGGKDGVTLLWDLTE-GKRLYSLDAG--------------SIINSLCFSPNRYW-LC 322 + AS G D +WDL++ G+ + DA + I+ ++PN W +C Sbjct: 331 ILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVIC 390 Query: 323 AATQDSI-KIWDLESKHIVQDLRPEVPVS 406 + ++D+I +IW + +++I D P++P S Sbjct: 391 SVSEDNIMQIWQM-AENIYNDEEPDIPAS 418
>RBBP7_XENLA (Q8AVH1) Histone-binding protein RBBP7 (Retinoblastoma-binding| protein 7) (RBBP-7) Length = 425 Score = 53.9 bits (128), Expect = 3e-07 Identities = 42/149 (28%), Positives = 79/149 (53%), Gaps = 19/149 (12%) Frame = +2 Query: 17 TGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRC-TLDGHGGYVSAVAVSPDG-S 190 T V+C+ F+P + + +GS D++V +W+L N KL+ + + H + V SP + Sbjct: 272 TAEVNCLSFNPYSEF-ILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVHWSPHNET 330 Query: 191 LCASGGKDGVTLLWDLTE-GKRLYSLDAG--------------SIINSLCFSPNRYW-LC 322 + AS G D +WDL++ G+ + DA + I+ ++PN W +C Sbjct: 331 ILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVIC 390 Query: 323 AATQDSI-KIWDLESKHIVQDLRPEVPVS 406 + ++D+I +IW + +++I D P++P S Sbjct: 391 SVSEDNIMQIWQM-AENIYNDEEPDIPAS 418
>COPB2_RAT (O35142) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| (p102) Length = 904 Score = 53.9 bits (128), Expect = 3e-07 Identities = 44/179 (24%), Positives = 78/179 (43%), Gaps = 7/179 (3%) Frame = +2 Query: 23 WVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCT--LDGHGGYVSAVAVSP-DGSL 193 ++ C+ P P I++ S D +K+W+ K C+ +GH YV + ++P D + Sbjct: 100 YIRCIAVHPTQ--PFILTSSDDMLIKLWDWDK-KWSCSQVFEGHTHYVMQIVINPKDNNQ 156 Query: 194 CASGGKDGVTLLWDLTEGKRLYSLDAG----SIINSLCFSPNRYWLCAATQDSIKIWDLE 361 AS D +W L ++L+ + I+ Y + A +KIWD + Sbjct: 157 FASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQ 216 Query: 362 SKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISGFSYSS*IMY 538 +K VQ P Q + +C ++ + + G DGT+RI+ S + S + Y Sbjct: 217 NKTCVQ-----TPEGHAQNV--SCATFHPELPIIITGSEDGTVRIWHSSTYRLESTLNY 268 Score = 48.5 bits (114), Expect = 1e-05 Identities = 36/153 (23%), Positives = 66/153 (43%), Gaps = 1/153 (0%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 V+C+ + P ++SG+ DR VK+W+ N T +GH VS P+ + +G Sbjct: 187 VNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTPEGHAQNVSCATFHPELPIIITG 246 Query: 206 GKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKI-WDLESKHIVQD 382 +DG +W Y L+ ++L + R W A+ + S + + I+ Sbjct: 247 SEDGTVRIWH----SSTYRLE-----STLNYGMERVWCVASLRGSNNVALGYDEGSIIVK 297 Query: 383 LRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTD 481 L E P +S A+G ++A +++ Sbjct: 298 LGREEP----------AMSMDANGKIIWAKHSE 320 Score = 41.2 bits (95), Expect = 0.002 Identities = 42/168 (25%), Positives = 69/168 (41%), Gaps = 8/168 (4%) Frame = +2 Query: 11 GPTGWVSCVRFSP---NNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSP 181 G T +V + +P N FA S S DR++KVW L + TL+GH V+ + Sbjct: 139 GHTHYVMQIVINPKDNNQFA----SASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYS 194 Query: 182 DGS--LCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLC--FSPNRYWLCAATQD-SIK 346 G SG D + +WD + K G N C F P + ++D +++ Sbjct: 195 GGDKPYLISGADDRLVKIWDY-QNKTCVQTPEGHAQNVSCATFHPELPIIITGSEDGTVR 253 Query: 347 IWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTI 490 IW + + L + M C++ + + GY +G+I Sbjct: 254 IWHSSTYRLESTL-------NYGMERVWCVASLRGSNNVALGYDEGSI 294
>WS17_SCHMA (Q26544) WD-repeat protein SL1-17| Length = 301 Score = 53.5 bits (127), Expect = 4e-07 Identities = 40/128 (31%), Positives = 64/128 (50%), Gaps = 6/128 (4%) Frame = +2 Query: 137 LDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLY-SLDA--GSIINSLCFSPN 307 LDGH V +V+ SPDG L AS D ++D+ +G+ + SL+ G +++ S N Sbjct: 182 LDGHATPVRSVSFSPDGRLLASASDDKQIKVFDVRDGRLVIPSLNGHKGWVVSVDFASDN 241 Query: 308 RYWLCAATQDSIKIWDL---ESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYT 478 R+ + A+T S++IWDL E KH +V C +S G+ + + Sbjct: 242 RHLVTASTDCSVRIWDLASKEEKHCFNTHEDQV----------WCARYSPQGNNIISVGD 291 Query: 479 DGTIRIYK 502 D +I IY+ Sbjct: 292 DRSIMIYQ 299 Score = 53.1 bits (126), Expect = 5e-07 Identities = 40/150 (26%), Positives = 69/150 (46%), Gaps = 7/150 (4%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCT--LDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLT 241 I++GS D + W TN +L+C +GH V +V ++ G+L AS D LLWDL Sbjct: 32 IITGSLDNGLIAWEWTNSQLKCLYQFEGHRLGVISVDINSTGTLAASSSLDSQILLWDLE 91 Query: 242 EGKRLYSLDAGSIIN-SLCFSPNRYWLCAATQ----DSIKIWDLESKHIVQDLRPEVPVS 406 G+ + D ++ FSP+ +L + + I + + + +Q Sbjct: 92 TGRLTKTYDGDPADTWTIAFSPDSRFLATGSHTGCVNMINVQTAQKEGSIQ--------- 142 Query: 407 SKQMLYCTCLSWSADGSTLYAGYTDGTIRI 496 + + L++ +DGS L AG +G + I Sbjct: 143 -LEGKFVYXLAYISDGSKLAAGTINGLVSI 171 Score = 48.9 bits (115), Expect = 1e-05 Identities = 39/159 (24%), Positives = 77/159 (48%), Gaps = 1/159 (0%) Frame = +2 Query: 35 VRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKD 214 + FSP++ + +GS V + N+ + ++ G +V +A DGS A+G + Sbjct: 109 IAFSPDS--RFLATGSHTGCVNMINVQTAQKEGSIQLEGKFVYXLAYISDGSKLAAGTIN 166 Query: 215 GVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQDLRP 391 G+ + DL G + + + S+ FSP+ L +A+ D IK++D V+D R Sbjct: 167 GLVSICDLETGSVQFLDGHATPVRSVSFSPDGRLLASASDDKQIKVFD------VRDGRL 220 Query: 392 EVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 +P + + + +++D L TD ++RI+ ++ Sbjct: 221 VIPSLNGHKGWVVSVDFASDNRHLVTASTDCSVRIWDLA 259 Score = 37.4 bits (85), Expect = 0.029 Identities = 23/77 (29%), Positives = 38/77 (49%) Frame = +2 Query: 2 SARGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSP 181 S G GWV V F+ +N +V+ S D SV++W+L + + + + H V SP Sbjct: 224 SLNGHKGWVVSVDFASDN--RHLVTASTDCSVRIWDLASKEEKHCFNTHEDQVWCARYSP 281 Query: 182 DGSLCASGGKDGVTLLW 232 G+ S G D +++ Sbjct: 282 QGNNIISVGDDRSIMIY 298
>APAF_MOUSE (O88879) Apoptotic protease-activating factor 1 (Apaf-1)| Length = 1249 Score = 53.5 bits (127), Expect = 4e-07 Identities = 40/142 (28%), Positives = 63/142 (44%), Gaps = 25/142 (17%) Frame = +2 Query: 74 SGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKR 253 S S D++ K+W+ L GH G V A S DG L A+G +G +W++++G+ Sbjct: 1102 STSADKTAKIWSFDLLSPLHELKGHNGCVRCSAFSLDGILLATGDDNGEIRIWNVSDGQL 1161 Query: 254 LYS----------LDAGSIINSLCFSPNR----------YWLCAATQDSIKIW-----DL 358 L+S G + +CFSP+ W AT DS + + +L Sbjct: 1162 LHSCAPISVEEGTATHGGWVTDVCFSPDSKTLVSAGGYLKWWNVATGDSSQTFYTNGTNL 1221 Query: 359 ESKHIVQDLRPEVPVSSKQMLY 424 + H+ D R V V + +LY Sbjct: 1222 KKIHVSPDFRTYVTVDNLGILY 1243 Score = 51.2 bits (121), Expect = 2e-06 Identities = 45/157 (28%), Positives = 72/157 (45%), Gaps = 11/157 (7%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSA--VAVSPDGSLCA 199 V C FS ++ I + S D+ VK+W+ KL T D H V+ S + L A Sbjct: 660 VLCCAFSSDD--SYIATCSADKKVKIWDSATGKLVHTYDEHSEQVNCCHFTNSSNHLLLA 717 Query: 200 SGGKDGVTLLWDLTEGK-RLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLESKHI 373 +G D LWDL + + R + +N FSP+ L + + D ++++WD+ S + Sbjct: 718 TGSNDFFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDELLASCSADGTLRLWDVRSANE 777 Query: 374 VQD-------LRPEVPVSSKQMLYCTCLSWSADGSTL 463 + L E P +++ C SWSADG + Sbjct: 778 RKSINVKRFFLSSEDPPEDVEVI-VKCCSWSADGDKI 813 Score = 37.4 bits (85), Expect = 0.029 Identities = 26/123 (21%), Positives = 51/123 (41%) Frame = +2 Query: 14 PTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSL 193 P VSC SP+ + G D ++K+ L N ++ + GH V + + DG Sbjct: 960 PEAQVSCCCLSPH--LEYVAFGDEDGAIKIIELPNNRVFSSGVGHKKAVRHIQFTADGKT 1017 Query: 194 CASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHI 373 S +D V +W+ G ++ + + L + ++K+W++ + I Sbjct: 1018 LISSSEDSVIQVWNWQTGDYVFLQAHQETVKDFRLLQDSRLLSWSFDGTVKVWNVITGRI 1077 Query: 374 VQD 382 +D Sbjct: 1078 ERD 1080 Score = 32.7 bits (73), Expect = 0.72 Identities = 40/156 (25%), Positives = 65/156 (41%), Gaps = 1/156 (0%) Frame = +2 Query: 41 FSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGV 220 FSP + I + V++WN+ + GH +V V SPDGS + D Sbjct: 848 FSPYDHLAVIALSQY--CVELWNIDSRLKVADCRGHLSWVHGVMFSPDGSSFLTASDDQT 905 Query: 221 TLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQ-DLRPEV 397 +W+ + + ++ I+ + F N + A D+I+ L + Q D PE Sbjct: 906 IRVWETKKVCKNSAIVLKQEID-VVFQENETMVLAV--DNIRGLQLIAGKTGQIDYLPEA 962 Query: 398 PVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 VS C CLS + + G DG I+I ++ Sbjct: 963 QVS------CCCLSPHLE--YVAFGDEDGAIKIIEL 990
>PK1IP_MOUSE (Q9DCE5) p21-activated protein kinase-interacting protein 1| (PAK1-interacting protein 1) (Putative PAK inhibitor Skb15) Length = 382 Score = 53.5 bits (127), Expect = 4e-07 Identities = 33/144 (22%), Positives = 67/144 (46%) Frame = +2 Query: 20 GWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCA 199 G V+C++F N ++SG+ D + +W++ K T H G+V+ +++ P G L Sbjct: 83 GTVTCLKFHGNQH---LISGAEDGHICIWDVKRWKCLKTFKAHRGHVTFLSIHPSGKLAL 139 Query: 200 SGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQ 379 S G D W+L EG+ + + + + +SP+ Q+ + ++ L + + Sbjct: 140 SVGTDKTLRTWNLIEGRSAFIKNIKENAHIVEWSPSGGKYIVVVQNKVDVYRLGTASVSG 199 Query: 380 DLRPEVPVSSKQMLYCTCLSWSAD 451 + +SS L + L+ + D Sbjct: 200 TITNGKRISSVTFLSDSVLAVAGD 223
>GBB_CRYPA (O14435) Guanine nucleotide-binding protein beta subunit| Length = 359 Score = 53.5 bits (127), Expect = 4e-07 Identities = 42/172 (24%), Positives = 83/172 (48%), Gaps = 6/172 (3%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDG- 187 G G++SC RF + +I++ S D + W++ + H G V +++++P Sbjct: 158 GHAGYLSCCRFINDR---SILTSSGDMTCMKWDIETGTKQIEFADHLGDVMSISLNPTNQ 214 Query: 188 SLCASGGKDGVTLLWDLTEGKRLYSLDAG--SIINSLCFSPNRYWLCAATQDSI-KIWDL 358 + SG D LWD+ GK + + AG S IN++ F P+ + + D+ +++D+ Sbjct: 215 NTFISGACDAFAKLWDIRAGKAVQTF-AGHESDINAIQFFPDGHSFVTGSDDATCRLFDI 273 Query: 359 ESKHIVQDLRPEVPVSSKQMLYC--TCLSWSADGSTLYAGYTDGTIRIYKIS 508 + E+ V + + C T ++ S G L+AGY D +++ ++ Sbjct: 274 RADR-------ELNVYGSESILCGITSVATSVSGRLLFAGYDDFECKVWDVT 318 Score = 53.1 bits (126), Expect = 5e-07 Identities = 46/164 (28%), Positives = 72/164 (43%), Gaps = 4/164 (2%) Frame = +2 Query: 20 GWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCA 199 G V + +P N T +SG+ D K+W++ K T GH ++A+ PDG Sbjct: 202 GDVMSISLNPTN-QNTFISGACDAFAKLWDIRAGKAVQTFAGHESDINAIQFFPDGHSFV 260 Query: 200 SGGKDGVTLLWDLTEGKRLYSLDAGSI---INSLCFSPNRYWLCAATQD-SIKIWDLESK 367 +G D L+D+ + L + SI I S+ S + L A D K+WD+ Sbjct: 261 TGSDDATCRLFDIRADRELNVYGSESILCGITSVATSVSGRLLFAGYDDFECKVWDVTRG 320 Query: 368 HIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 V L V + + +CL S DG +L G D ++I+ Sbjct: 321 EKVGSL-----VGHENRV--SCLGVSNDGISLCTGSWDSLLKIW 357 Score = 31.2 bits (69), Expect = 2.1 Identities = 26/107 (24%), Positives = 47/107 (43%), Gaps = 8/107 (7%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 +VS S D + +W+ + +V A +P G+ A GG D + +++L + Sbjct: 86 LVSASQDGKLIIWDAYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLNQN 145 Query: 248 K-------RLYSLDAGSIINSLC-FSPNRYWLCAATQDSIKIWDLES 364 + R S AG + S C F +R L ++ + WD+E+ Sbjct: 146 RDGPTRVARELSGHAGYL--SCCRFINDRSILTSSGDMTCMKWDIET 190 Score = 30.4 bits (67), Expect = 3.6 Identities = 19/81 (23%), Positives = 38/81 (46%), Gaps = 2/81 (2%) Frame = +2 Query: 122 KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLD-AGSIINSLCF 298 K + TL GH + A+ S D S +DG ++WD +++++ S + + + Sbjct: 62 KTKRTLKGHLAKIYAMHWSTDRRHLVSASQDGKLIIWDAYTTNKVHAIPLRSSWVMTCAY 121 Query: 299 SPN-RYWLCAATQDSIKIWDL 358 +P+ Y C + I++L Sbjct: 122 APSGNYVACGGLDNICSIYNL 142
>TEP1_MOUSE (P97499) Telomerase protein component 1 (Telomerase-associated| protein 1) (Telomerase protein 1) (p240) (p80 homolog) Length = 2629 Score = 53.1 bits (126), Expect = 5e-07 Identities = 44/166 (26%), Positives = 67/166 (40%), Gaps = 2/166 (1%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 ++CV F P + +GSW S+ + K+ L G V ++A + G + A G Sbjct: 1810 LNCVAFHPEG--QVVATGSWAGSITFFQADGLKVTKELGAPGPSVCSLAFNKPGKIVAVG 1867 Query: 206 GKDGVTLLWDLTEGKRLYSLDA--GSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQ 379 DG LW EG RL + A G + L +L A ++W Sbjct: 1868 RIDGTVELWAWQEGARLAAFPAQCGCVSAVLFLHAGDRFLTAGEDGKAQLWSGFLG---- 1923 Query: 380 DLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISGFS 517 RP + S + ++ + DG + GY + I IYKIS S Sbjct: 1924 --RPRGCLGSLPLSPALSVALNPDGDQVAVGYREDGINIYKISSGS 1967 Score = 39.3 bits (90), Expect = 0.008 Identities = 38/155 (24%), Positives = 68/155 (43%), Gaps = 10/155 (6%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVS----PDGS-----LCASGGKDGV 220 IVS S D ++KVW+ +L ++ H G +S A + P G L + G DG Sbjct: 2169 IVSVSRDGTLKVWDHQGVELT-SIPAHSGPISQCAAALEPRPGGQPGSELLVVTVGLDGA 2227 Query: 221 TLLWDLTEGKRLYSLDAGS-IINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEV 397 T LW ++ +L S + + S L + S+++W + K +P Sbjct: 2228 TKLWHPLLVCQIRTLQGHSGPVTAAAASEASGLLLTSDDSSVQLWQIP-KEADDSYKPRS 2286 Query: 398 PVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYK 502 V+ T ++W+ DGS + +G G + +++ Sbjct: 2287 SVA------ITAVAWAPDGSMVVSGNEAGELTLWQ 2315 Score = 37.7 bits (86), Expect = 0.022 Identities = 29/106 (27%), Positives = 50/106 (47%), Gaps = 12/106 (11%) Frame = +2 Query: 68 IVSGSWDRSVKVW--------NLTNCKLRCT--LDGHGGYVSAVAVSPDGSLCASGGKDG 217 + + S D +V++W ++ +L C L GH G V + SPDG + A+ G+D Sbjct: 2032 MAAASEDFTVRLWPRQLLTQPHVHAVELPCCAELRGHEGPVCCCSFSPDGGILATAGRDR 2091 Query: 218 VTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWL--CAATQDSIKI 349 L WD+ + ++ S +R W+ CA T+D+I + Sbjct: 2092 NLLCWDM-------KIAQAPLLIHTFSSCHRDWITGCAWTKDNILV 2130 Score = 35.4 bits (80), Expect = 0.11 Identities = 28/141 (19%), Positives = 58/141 (41%), Gaps = 1/141 (0%) Frame = +2 Query: 80 SWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLY 259 ++D +++W+L + H ++ +SPD L A+ G LWD G+ + Sbjct: 1743 TFDGHLELWDLQHGCWVFQTKAHQYQITGCCLSPDRRLLATVCLGGYLKLWDTVRGQLAF 1802 Query: 260 SLDAGSIINSLCFSPNRYWLCAAT-QDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCL 436 +N + F P + + SI + + + ++L P C+ L Sbjct: 1803 QYTHPKSLNCVAFHPEGQVVATGSWAGSITFFQADGLKVTKELGAPGP------SVCS-L 1855 Query: 437 SWSADGSTLYAGYTDGTIRIY 499 +++ G + G DGT+ ++ Sbjct: 1856 AFNKPGKIVAVGRIDGTVELW 1876 Score = 34.7 bits (78), Expect = 0.19 Identities = 22/85 (25%), Positives = 43/85 (50%), Gaps = 1/85 (1%) Frame = +2 Query: 86 DRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSL 265 D SV++W + ++AVA +PDGS+ SG + G LW + K + + Sbjct: 2266 DSSVQLWQIPKEADDSYKPRSSVAITAVAWAPDGSMVVSGNEAGELTLWQ--QAKAVATA 2323 Query: 266 DA-GSIINSLCFSPNRYWLCAATQD 337 A G + + + +S N +++ +A ++ Sbjct: 2324 QAPGRVSHLIWYSANSFFVLSANEN 2348 Score = 33.5 bits (75), Expect = 0.42 Identities = 28/137 (20%), Positives = 54/137 (39%), Gaps = 4/137 (2%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDG----HGGYVSAVAV 175 RG G V C FSP+ + + DR++ W++ + + H +++ A Sbjct: 2066 RGHEGPVCCCSFSPDG--GILATAGRDRNLLCWDMKIAQAPLLIHTFSSCHRDWITGCAW 2123 Query: 176 SPDGSLCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWD 355 + D L S DG LW+ G++L S + + + + ++K+WD Sbjct: 2124 TKDNIL-VSCSSDGSVGLWNPEAGQQLGQFSGHQSAVSAVVAVEEHIVSVSRDGTLKVWD 2182 Query: 356 LESKHIVQDLRPEVPVS 406 + + P+S Sbjct: 2183 HQGVELTSIPAHSGPIS 2199
>COPB2_CAEEL (Q20168) Probable coatomer subunit beta' (Beta'-coat protein)| (Beta'-COP) Length = 1000 Score = 53.1 bits (126), Expect = 5e-07 Identities = 28/83 (33%), Positives = 43/83 (51%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 V+CV + P I+SG+ D VK+W+ N TLDGH VS+V P+ L +G Sbjct: 188 VNCVDYYHGGEKPYIISGADDHLVKIWDYQNKTCVQTLDGHAQNVSSVCFHPELPLIITG 247 Query: 206 GKDGVTLLWDLTEGKRLYSLDAG 274 +D LW ++ ++L+ G Sbjct: 248 SEDSTVRLWHANTYRQEHTLNYG 270 Score = 47.4 bits (111), Expect = 3e-05 Identities = 39/169 (23%), Positives = 72/169 (42%), Gaps = 4/169 (2%) Frame = +2 Query: 2 SARGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSP 181 S G T +V + +P + T + S D++VKVW + TL+GH V+ V Sbjct: 137 SFEGHTHYVMQIAINPKD-NNTFATASLDKTVKVWQFGSNVPNFTLEGHEKGVNCVDYYH 195 Query: 182 DGS--LCASGGKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQDS-IKI 349 G SG D + +WD + +LD ++S+CF P + ++DS +++ Sbjct: 196 GGEKPYIISGADDHLVKIWDYQNKTCVQTLDGHAQNVSSVCFHPELPLIITGSEDSTVRL 255 Query: 350 WDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRI 496 W + L + + C+ +T+ GY +G++ + Sbjct: 256 WHANTYRQEHTL-------NYGLERVWCIQAQKGANTIAIGYDEGSVTL 297
>YAGE_SCHPO (Q9UTN4) Hypothetical WD-repeat protein C12G12.14c in chromosome I| Length = 509 Score = 53.1 bits (126), Expect = 5e-07 Identities = 47/162 (29%), Positives = 69/162 (42%), Gaps = 5/162 (3%) Frame = +2 Query: 35 VRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKD 214 V FSPN+ V+ S D S+KVWN L GHG V V P L ASG KD Sbjct: 170 VAFSPND--SKFVTASDDGSLKVWNFHMSTEELKLTGHGWDVKTVDWHPSKGLLASGSKD 227 Query: 215 GVTLLWDLTEGKRLYSLDA-GSIINSLCFSPN---RYWLCAATQDSIKIWDLESKHIVQD 382 + WD G + +L + I F N Y + + +++DL + V+ Sbjct: 228 NLVKFWDPRTGTCIATLHGHKNTIMQASFQKNFGSNYLATVSRDSTCRVFDLRAMKDVRV 287 Query: 383 LRPEVPVSSKQMLYCTCLSW-SADGSTLYAGYTDGTIRIYKI 505 LR K + C++W + L G +DG++ Y + Sbjct: 288 LRGH----EKDV---NCVTWHPLYPNLLTTGGSDGSVNHYSL 322 Score = 31.6 bits (70), Expect = 1.6 Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 4/100 (4%) Frame = +2 Query: 68 IVSGSWDRSVKVW--NLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL- 238 ++SG VK + NL N K+ + H V VA SP+ S + DG +W+ Sbjct: 138 LISGDGGGMVKYFEPNLNNVKI---VQAHEMEVRDVAFSPNDSKFVTASDDGSLKVWNFH 194 Query: 239 TEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDS-IKIWD 355 + L G + ++ + P++ L + ++D+ +K WD Sbjct: 195 MSTEELKLTGHGWDVKTVDWHPSKGLLASGSKDNLVKFWD 234
>WDR33_HUMAN (Q9C0J8) WD-repeat protein 33 (WD-repeat protein WDC146)| Length = 1336 Score = 52.8 bits (125), Expect = 7e-07 Identities = 43/159 (27%), Positives = 75/159 (47%), Gaps = 8/159 (5%) Frame = +2 Query: 53 NFAPT---IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVT 223 +F+PT + S D +V++W+ C L GHG V V P L SG KD Sbjct: 209 SFSPTDNKFATCSDDGTVRIWDFLRCHEERILRGHGADVKCVDWHPTKGLVVSGSKDSQQ 268 Query: 224 LL--WDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQDSI-KIWDLESKHIVQDLRP 391 + WD G+ L +L A + + + + N WL A++D + K++D +++L+ Sbjct: 269 PIKFWDPKTGQSLATLHAHKNTVMEVKLNLNGNWLLTASRDHLCKLFD------IRNLKE 322 Query: 392 EVPVSSKQMLYCTCLSWSADGSTLYA-GYTDGTIRIYKI 505 E+ V T ++W L+A G +DG++ + + Sbjct: 323 ELQVFRGHKKEATAVAWHPVHEGLFASGGSDGSLLFWHV 361 Score = 30.8 bits (68), Expect = 2.7 Identities = 38/170 (22%), Positives = 72/170 (42%), Gaps = 6/170 (3%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWD--RSVKVWNLTNCKLRCTLDGHGGYVSAVAVSP 181 RG V CV + P +VSGS D + +K W+ + TL H V V ++ Sbjct: 241 RGHGADVKCVDWHPTK--GLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKLNL 298 Query: 182 DGSLCASGGKDGVTLLWDLTEGKRLYSLDAG--SIINSLCFSPNRYWLCAA--TQDSIKI 349 +G+ + +D + L+D+ K + G ++ + P L A+ + S+ Sbjct: 299 NGNWLLTASRDHLCKLFDIRNLKEELQVFRGHKKEATAVAWHPVHEGLFASGGSDGSLLF 358 Query: 350 WDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 W + + V + ++ + M++ L+W G L +G D T + + Sbjct: 359 WHVGVEKEVGGME----MAHEGMIW--SLAWHPLGHILCSGSNDHTSKFW 402
>U3IP2_HUMAN (O43818) U3 small nucleolar RNA-interacting protein 2 (U3 small| nucleolar ribonucleoproptein-associated 55-kDa protein) (U3 snoRNP-associated 55-kDa protein) (U3-55K) Length = 475 Score = 52.8 bits (125), Expect = 7e-07 Identities = 44/180 (24%), Positives = 83/180 (46%), Gaps = 14/180 (7%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLD-----------GHGG 154 RG ++C+ +P++ A I S + D S+ W++ + + + GH Sbjct: 143 RGHQLSITCLVVTPDDSA--IFSAAKDCSIIKWSVESGRKLHVIPRAKKGAEGKPPGHSS 200 Query: 155 YVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAAT 331 +V +A+S DG ASG + + L+W+ + LY+ ++ L F + L + + Sbjct: 201 HVLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTHQLYSTS 260 Query: 332 QD-SIKIWDLESKHIVQDL-RPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 D S+K+W++ V+ L + V++ L C + AG DGT+R++KI Sbjct: 261 HDRSVKVWNVAENSYVETLFGHQDAVAALDALSREC--------CVTAGGRDGTVRVWKI 312 Score = 49.3 bits (116), Expect = 7e-06 Identities = 29/100 (29%), Positives = 44/100 (44%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 + S S DRSVKVWN+ TL GH V+A+ +GG+DG +W + E Sbjct: 256 LYSTSHDRSVKVWNVAENSYVETLFGHQDAVAALDALSRECCVTAGGRDGTVRVWKIPEE 315 Query: 248 KRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESK 367 +L I+ + + + A S+ +W L K Sbjct: 316 SQLVFYGHQGSIDCIHLINEEHMVSGADDGSVALWGLSKK 355 Score = 32.3 bits (72), Expect = 0.94 Identities = 31/142 (21%), Positives = 57/142 (40%), Gaps = 14/142 (9%) Frame = +2 Query: 137 LDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSL----------DAGSIIN 286 L GH ++ + V+PD S S KD + W + G++L+ + G + Sbjct: 142 LRGHQLSITCLVVTPDDSAIFSAAKDCSIIKWSVESGRKLHVIPRAKKGAEGKPPGHSSH 201 Query: 287 SLCF---SPNRYWLCAATQDSIKIWDLES-KHIVQDLRPEVPVSSKQMLYCTCLSWSADG 454 LC S +Y I IW+ +S +H+ VS L++ Sbjct: 202 VLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSG--------LAFRRGT 253 Query: 455 STLYAGYTDGTIRIYKISGFSY 520 LY+ D +++++ ++ SY Sbjct: 254 HQLYSTSHDRSVKVWNVAENSY 275
>FBXW7_HUMAN (Q969H0) F-box/WD-repeat protein 7 (F-box and WD-40 domain protein| 7) (F-box protein FBX30) (hCdc4) (Archipelago homolog) (hAgo) (SEL-10) Length = 707 Score = 52.8 bits (125), Expect = 7e-07 Identities = 40/165 (24%), Positives = 73/165 (44%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G V CV++ +VSG++D VKVW+ TL GH V ++ DG Sbjct: 499 GHVAAVRCVQYDGRR----VVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGI 552 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKH 370 SG D +WD+ G +++L + S + + ++KIWD+++ Sbjct: 553 HVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQ 612 Query: 371 IVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 +Q L+ +K TCL ++ + + DGT++++ + Sbjct: 613 CLQTLQG----PNKHQSAVTCLQFNK--NFVITSSDDGTVKLWDL 651 Score = 48.9 bits (115), Expect = 1e-05 Identities = 40/147 (27%), Positives = 66/147 (44%), Gaps = 1/147 (0%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 I+SGS DR++KVWN + TL GH V + + SG +D +WD+ G Sbjct: 434 IISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETG 491 Query: 248 KRLYSLDAGSIINSLCFS-PNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLY 424 + L+ L G + C R + A +K+WD E++ + L+ +Y Sbjct: 492 QCLHVL-MGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQ-----GHTNRVY 545 Query: 425 CTCLSWSADGSTLYAGYTDGTIRIYKI 505 S DG + +G D +IR++ + Sbjct: 546 ----SLQFDGIHVVSGSLDTSIRVWDV 568 Score = 46.6 bits (109), Expect = 5e-05 Identities = 38/159 (23%), Positives = 75/159 (47%), Gaps = 1/159 (0%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 ++C++F N IVSGS D ++KVW+ K TL GH G V + + ++ SG Sbjct: 384 ITCLQFCGNR----IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMR--DNIIISG 437 Query: 206 GKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQD 382 D +W+ G+ +++L G C + + + ++D ++++WD+E+ + Sbjct: 438 STDRTLKVWNAETGECIHTL-YGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHV 496 Query: 383 LRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 L V C+ + DG + +G D ++++ Sbjct: 497 LMGHVAA-------VRCVQY--DGRRVVSGAYDFMVKVW 526 Score = 38.1 bits (87), Expect = 0.017 Identities = 23/73 (31%), Positives = 39/73 (53%), Gaps = 4/73 (5%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVA-VSPDGSLCASGGKDGVTLLWDLTE 244 +VSG+ D +VK+W++ + TL G + SAV + + + + DG LWDL Sbjct: 594 LVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKT 653 Query: 245 G---KRLYSLDAG 274 G + L +L++G Sbjct: 654 GEFIRNLVTLESG 666
>GBB_NICPL (P93339) Guanine nucleotide-binding protein beta subunit (NpGPB1)| Length = 377 Score = 52.8 bits (125), Expect = 7e-07 Identities = 49/175 (28%), Positives = 74/175 (42%), Gaps = 8/175 (4%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNL-TNCKLRCTLDGHGGYVSAVAVSPDG 187 G T V V S +N VSGS D + ++W+ + + T H G V+ V PDG Sbjct: 202 GHTADVQSVSISSSN-PRLFVSGSCDTTARLWDTRVASRAQRTFYCHEGDVNTVKFFPDG 260 Query: 188 SLCASGGKDGVTLLWDLTEGKRL--YSLDAGS----IINSLCFS-PNRYWLCAATQDSIK 346 + +G +DG L+D+ G +L Y G + S+ FS R + Sbjct: 261 NRFGTGSEDGTCRLFDIRTGHQLQVYYQPHGDGDIPHVTSMAFSISGRLLFVRYSNGDCY 320 Query: 347 IWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISG 511 +WD +V +L V + +CL SADG L G D ++I+ G Sbjct: 321 VWDTLLAKVVLNLG---AVQNSHEGXISCLGLSADGXXLCTGSWDTNLKIWAFGG 372 Score = 50.8 bits (120), Expect = 3e-06 Identities = 48/188 (25%), Positives = 75/188 (39%), Gaps = 24/188 (12%) Frame = +2 Query: 14 PTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLT-------NCKLRCTLDGHGGYVSAVA 172 P WV FSP+ + + G D ++NL N + L GH GYVS+ Sbjct: 106 PCAWVMTCAFSPSGHS--VACGGLDSVCSIFNLNSPIDKDGNHPVSRMLSGHKGYVSSCQ 163 Query: 173 VSPDGS--LCASGGKDGVTLLWDLTEGKRL----------YSLDAGSIINSLCFSPNRYW 316 PD L S G D +LWD+T G R ++ D S+ S+ S R + Sbjct: 164 YVPDEDTHLITSSG-DQTCVLWDITTGLRTSVFGGEFQFGHTADVQSV--SISSSNPRLF 220 Query: 317 LCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYC-----TCLSWSADGSTLYAGYTD 481 + + + ++WD V +++ YC + + DG+ G D Sbjct: 221 VSGSCDTTARLWD-----------TRVASRAQRTFYCHEGDVNTVKFFPDGNRFGTGSED 269 Query: 482 GTIRIYKI 505 GT R++ I Sbjct: 270 GTCRLFDI 277 Score = 30.8 bits (68), Expect = 2.7 Identities = 20/88 (22%), Positives = 46/88 (52%), Gaps = 2/88 (2%) Frame = +2 Query: 107 NLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLDAG-SII 283 +L C++ L GH G V ++ +P+ + S +DG ++W+ ++ +++ + + Sbjct: 54 DLVCCRI---LQGHTGKVYSLDWTPEKNRIVSASQDGRLIVWNALTSQKTHAIKLPCAWV 110 Query: 284 NSLCFSPNRYWLCAATQDSI-KIWDLES 364 + FSP+ + + DS+ I++L S Sbjct: 111 MTCAFSPSGHSVACGGLDSVCSIFNLNS 138
>FAN_MOUSE (O35242) Protein FAN (Factor associated with N-SMase activation)| (Factor associated with neutral sphingomyelinase activation) Length = 920 Score = 52.4 bits (124), Expect = 9e-07 Identities = 36/163 (22%), Positives = 74/163 (45%), Gaps = 11/163 (6%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDG---------HGGYVSAVAVSPDGSLCASGGKDGV 220 + SGSWD +VKVW+ ++ T H V+ + ++ +L SG K+G+ Sbjct: 730 LYSGSWDSTVKVWSGVPAEMPGTKRHQFDLLAELEHDVSVNTINLNAVSTLLVSGTKEGM 789 Query: 221 TLLWDLTEGKRLY--SLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPE 394 +WDLT L+ S +G++ ++ +R+ L + + D+++ ++ + + Sbjct: 790 VNIWDLTTATLLHQTSCHSGTVCDAAFSPDSRHILSTGVDGCLNVIDVQTGMLISSMASD 849 Query: 395 VPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKISGFSYS 523 P C W DG+++ +G G + ++ + G S Sbjct: 850 EPQ--------RCFVW--DGNSVLSGSRSGELLVWDLLGAKVS 882 Score = 44.7 bits (104), Expect = 2e-04 Identities = 37/160 (23%), Positives = 63/160 (39%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 VS + N + +VSG+ + V +W+LT L H G V A SPD S Sbjct: 767 VSVNTINLNAVSTLLVSGTKEGMVNIWDLTTATLLHQTSCHSGTVCDAAFSPDSRHILST 826 Query: 206 GKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDL 385 G DG + D+ G + S+ + + N L + + +WDL + + + Sbjct: 827 GVDGCLNVIDVQTGMLISSMASDEPQRCFVWDGNSV-LSGSRSGELLVWDLLGAKVSERI 885 Query: 386 RPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 + TC+ + S++ G D I +K+ Sbjct: 886 QGHTGA-------VTCMWMNEQCSSIITGGEDRQIMFWKL 918
>TEP1_RAT (O08653) Telomerase protein component 1 (rTLP1)| (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p230) (p80 telomerase homolog) Length = 2629 Score = 52.4 bits (124), Expect = 9e-07 Identities = 42/163 (25%), Positives = 65/163 (39%), Gaps = 2/163 (1%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 ++C+ F P + +G+W V + K+ L G G V +A S G + A G Sbjct: 1814 LNCITFHPEG--QVVATGNWSGIVTFFQADGLKVTKELGGPGPSVRTLAFSAPGKVVALG 1871 Query: 206 GKDGVTLLWDLTEGKRLYSLDA--GSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQ 379 DG LW EG RL + A G + L +L A ++W Sbjct: 1872 RIDGTVELWAWQEGTRLAAFPAQCGGVSTVLFLHAGGRFLTAGEDGKAQLWSGFLG---- 1927 Query: 380 DLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKIS 508 RP + S + ++ + DG + GY I+IY+IS Sbjct: 1928 --RPRGCLGSLYLSPALSVALNPDGDQVAVGYRGDGIKIYRIS 1968 Score = 38.9 bits (89), Expect = 0.010 Identities = 36/155 (23%), Positives = 68/155 (43%), Gaps = 10/155 (6%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVS----PDGS-----LCASGGKDGV 220 IVS S D ++KVW+ +L ++ H G +S A + P G + + G DG Sbjct: 2172 IVSVSRDGTLKVWDRQGVELT-SIPAHSGPISQCAAALEPRPAGQPGSELMVVTVGLDGA 2230 Query: 221 TLLWDLTEGKRLYSLDAGS-IINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEV 397 T LW ++++L S + + S L + S+++W + K +P Sbjct: 2231 TKLWHPLLVCQIHTLQGHSGPVTAAAASEASGLLLTSDNSSVRLWQIP-KEADDTCKP-- 2287 Query: 398 PVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYK 502 + T ++W+ DGS + +G G + +++ Sbjct: 2288 ----RSSAVITAVAWAPDGSLVVSGNEAGELTLWQ 2318 Score = 37.0 bits (84), Expect = 0.038 Identities = 34/105 (32%), Positives = 52/105 (49%), Gaps = 11/105 (10%) Frame = +2 Query: 68 IVSGSWDRSVKVWN---LTNC----KLRCT--LDGHGGYVSAVAVSPDGSLCASGGKDGV 220 + S S D +V++W LT +L C L GH G V + SPDG + A+ G+D Sbjct: 2036 LASASEDFTVRLWPRQLLTQPHAVEELPCAAELRGHEGPVCCCSFSPDGRILATAGRDRN 2095 Query: 221 TLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWL--CAATQDSIKI 349 L WD+ + A +I++ S +R W+ C T+D+I I Sbjct: 2096 LLCWDVKVAQ------APLLIHTFS-SCHRDWITGCTWTKDNILI 2133 Score = 36.6 bits (83), Expect = 0.050 Identities = 28/141 (19%), Positives = 56/141 (39%), Gaps = 1/141 (0%) Frame = +2 Query: 80 SWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLY 259 ++D +++W+L + H ++ +SPD L A+ G LWD +G+ + Sbjct: 1747 TFDGLLELWDLQHGCWVFQTKAHQYQITGCCLSPDRRLLATVCLGGYVKLWDTVQGQLAF 1806 Query: 260 SLDAGSIINSLCFSPNRYWLCAATQDSI-KIWDLESKHIVQDLRPEVPVSSKQMLYCTCL 436 +N + F P + I + + + ++L P L Sbjct: 1807 QYTHPKSLNCITFHPEGQVVATGNWSGIVTFFQADGLKVTKELGGPGP-------SVRTL 1859 Query: 437 SWSADGSTLYAGYTDGTIRIY 499 ++SA G + G DGT+ ++ Sbjct: 1860 AFSAPGKVVALGRIDGTVELW 1880 Score = 35.4 bits (80), Expect = 0.11 Identities = 25/95 (26%), Positives = 46/95 (48%), Gaps = 5/95 (5%) Frame = +2 Query: 92 SVKVWNLTN-----CKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRL 256 SV++W + CK R + ++AVA +PDGSL SG + G LW + Sbjct: 2271 SVRLWQIPKEADDTCKPRSS-----AVITAVAWAPDGSLVVSGNEAGELTLWQKAQAVAT 2325 Query: 257 YSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLE 361 + G + + + S N +++ +A +++ W +E Sbjct: 2326 -ARAPGRVSDLIWCSANAFFVLSA-NENVSEWQVE 2358 Score = 31.6 bits (70), Expect = 1.6 Identities = 28/139 (20%), Positives = 55/139 (39%), Gaps = 6/139 (4%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDG----HGGYVSAVAV 175 RG G V C FSP+ + + DR++ W++ + + H +++ Sbjct: 2069 RGHEGPVCCCSFSPDG--RILATAGRDRNLLCWDVKVAQAPLLIHTFSSCHRDWITGCTW 2126 Query: 176 SPDGSL--CASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKI 349 + D L C+S G G LW+ G++L S + + + + ++K+ Sbjct: 2127 TKDNILISCSSDGSVG---LWNPEAGQQLGQFPGHQSAVSAVVAVEEHIVSVSRDGTLKV 2183 Query: 350 WDLESKHIVQDLRPEVPVS 406 WD + + P+S Sbjct: 2184 WDRQGVELTSIPAHSGPIS 2202
>U3IP2_MOUSE (Q91WM3) U3 small nucleolar RNA-interacting protein 2 (U3 small| nucleolar ribonucleoproptein-associated 55-kDa protein) (U3 snoRNP-associated 55-kDa protein) (U3-55K) Length = 475 Score = 52.4 bits (124), Expect = 9e-07 Identities = 46/180 (25%), Positives = 82/180 (45%), Gaps = 14/180 (7%) Frame = +2 Query: 8 RGPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNL-TNCKLRCTLD----------GHGG 154 RG ++C+ +P++ A I S + D ++ W++ T KL GH Sbjct: 143 RGHQLSITCLVITPDDLA--IFSAAKDCTIIKWSVETGRKLHVIPRAKKGAQGQPAGHSS 200 Query: 155 YVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAAT 331 +V +A+S DG ASG + + L+W+ + LY+ ++ L F + L + + Sbjct: 201 HVLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRKGTHQLYSTS 260 Query: 332 QD-SIKIWDLESKHIVQDL-RPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 D S+K+W+ V+ L + V++ L C + AG DGT+R++KI Sbjct: 261 HDRSVKVWNAAENSYVETLFGHQDAVAALDALSREC--------CVTAGGRDGTVRVWKI 312 Score = 48.5 bits (114), Expect = 1e-05 Identities = 29/100 (29%), Positives = 43/100 (43%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 + S S DRSVKVWN TL GH V+A+ +GG+DG +W + E Sbjct: 256 LYSTSHDRSVKVWNAAENSYVETLFGHQDAVAALDALSRECCVTAGGRDGTVRVWKIPEE 315 Query: 248 KRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESK 367 +L I+ + + + A S+ +W L K Sbjct: 316 SQLVFYGHQGSIDCIHLINEEHMVSGADDGSVALWGLSKK 355 Score = 30.4 bits (67), Expect = 3.6 Identities = 21/89 (23%), Positives = 36/89 (40%), Gaps = 13/89 (14%) Frame = +2 Query: 137 LDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSL----------DAGSIIN 286 L GH ++ + ++PD S KD + W + G++L+ + AG + Sbjct: 142 LRGHQLSITCLVITPDDLAIFSAAKDCTIIKWSVETGRKLHVIPRAKKGAQGQPAGHSSH 201 Query: 287 SLCF---SPNRYWLCAATQDSIKIWDLES 364 LC S +Y I IW+ +S Sbjct: 202 VLCMAISSDGKYLASGDRSKLILIWEAQS 230
>MORG1_XENLA (Q3KQ62) Mitogen-activated protein kinase organizer 1 (MAPK| organizer 1) Length = 314 Score = 52.4 bits (124), Expect = 9e-07 Identities = 55/196 (28%), Positives = 82/196 (41%), Gaps = 37/196 (18%) Frame = +2 Query: 20 GWVSCVRFSPN-NFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLC 196 G V VRF+ + N+ T S D+S+K+WN L T GHG V A S D S Sbjct: 26 GAVRAVRFNVDGNYCMTCGS---DKSLKLWNPHKGSLLKTYSGHGYEVLDTAGSCDNSQL 82 Query: 197 ASGGKDGVTLLWDLTEGK--RLYSLDAGSIINSLCFSPNRYWLCAATQD-SIKIWDLESK 367 S D +LWD+ +G+ R + AG +N + F+ + + + D SI+ WD S+ Sbjct: 83 CSCSSDKTVILWDVAQGQVVRKFRGHAGK-VNCVQFNEEATVIISGSIDSSIRCWDCRSR 141 Query: 368 H--------IVQDLRPEVPVSSKQMLY-------------------------CTCLSWSA 448 +D V VS+ ++L TC+S+S Sbjct: 142 RPDAIQIMDEAKDGISSVKVSAHEILAGSVDGNLRRYDLRKGEMCADYLGSPITCVSFSQ 201 Query: 449 DGSTLYAGYTDGTIRI 496 D L A D T+R+ Sbjct: 202 DSQCLLASSLDSTLRL 217 Score = 44.3 bits (103), Expect = 2e-04 Identities = 28/112 (25%), Positives = 53/112 (47%), Gaps = 3/112 (2%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGG--YVSAVAVSPDGSLCA 199 ++CV FS ++ +++ S D ++++ + +L GH Y +S + Sbjct: 194 ITCVSFSQDS--QCLLASSLDSTLRLLDKDTGELLGEYTGHQNLSYKLDSCLSEKDTHVL 251 Query: 200 SGGKDGVTLLWDLTEGKRLYSLDAG-SIINSLCFSPNRYWLCAATQDSIKIW 352 S +DG WDL EG + L G +++ SL F P L A++ +++W Sbjct: 252 SCSEDGTVCFWDLVEGSLVLKLPVGKAVVQSLSFHPTECCLLTASEGGVQVW 303 Score = 40.8 bits (94), Expect = 0.003 Identities = 28/128 (21%), Positives = 57/128 (44%), Gaps = 2/128 (1%) Frame = +2 Query: 122 KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRL--YSLDAGSIINSLC 295 KL+ L+ + G V AV + DG+ C + G D LW+ +G L YS ++++ Sbjct: 16 KLQHKLECNQGAVRAVRFNVDGNYCMTCGSDKSLKLWNPHKGSLLKTYSGHGYEVLDTAG 75 Query: 296 FSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGY 475 N ++ ++ +WD+ +V+ R C+ ++ + + + +G Sbjct: 76 SCDNSQLCSCSSDKTVILWDVAQGQVVRKFRGHAG-------KVNCVQFNEEATVIISGS 128 Query: 476 TDGTIRIY 499 D +IR + Sbjct: 129 IDSSIRCW 136
>WDR16_MOUSE (Q5F201) WD-repeat protein 16| Length = 620 Score = 52.4 bits (124), Expect = 9e-07 Identities = 28/110 (25%), Positives = 52/110 (47%), Gaps = 4/110 (3%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNC---KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL 238 I+SG + V+VW + C KL L H VS + V + C + DG ++WDL Sbjct: 432 IISGGGEGEVRVWQV-GCQTQKLEEALKEHKSSVSCIRVKKNNEECVTASTDGTCIIWDL 490 Query: 239 TEGKRLYSLDAGSIINSLCFSPNRYW-LCAATQDSIKIWDLESKHIVQDL 385 +R + A ++ +C+ P + + + T I W++ ++++L Sbjct: 491 VRLRRNQMILANTLFQCVCYHPEEFQIITSGTDRKIAYWEVFDGSVIREL 540 Score = 42.7 bits (99), Expect = 7e-04 Identities = 36/133 (27%), Positives = 60/133 (45%), Gaps = 10/133 (7%) Frame = +2 Query: 137 LDGHGGYVSAVAVSPDGSLCASG-----GKDGVTLLWDLTEGKRL--YSLDAGSIINSLC 295 L GHG VS V +S +G ASG G +LWD + + + SL G I +L Sbjct: 60 LHGHGNNVSCVTISKEGDYIASGQVTFMGFKADIILWDFKKRELIARLSLHKGK-IEALA 118 Query: 296 FSPNRYWLCA---ATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLY 466 FSPN +L + S+ +W + + D P + + T + +S ++ Sbjct: 119 FSPNDLYLVSLGGPDDGSVVVWSIAKR----DAICGSPAAGLNVGNATSVVFSRCRDEMF 174 Query: 467 AGYTDGTIRIYKI 505 +GTIR++++ Sbjct: 175 VTAGNGTIRVWEL 187 Score = 39.7 bits (91), Expect = 0.006 Identities = 26/110 (23%), Positives = 52/110 (47%), Gaps = 3/110 (2%) Frame = +2 Query: 32 CVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGH-GGYVSAVAVSPDGSLCASGG 208 CV + P F I++ DR + W + + + L+G G ++ + ++ +G +GG Sbjct: 507 CVCYHPEEFQ--IITSGTDRKIAYWEVFDGSVIRELEGSLSGSINGMDITQEGGHFVTGG 564 Query: 209 KDGVTLLWDLTEGKRLY-SLDAGSIINSLCFSP-NRYWLCAATQDSIKIW 352 D + +WD EG+ + + I ++ SP N+Y + + +I W Sbjct: 565 HDHLVKVWDYNEGEVTHVGVGHSGNIMAMRISPGNQYIVSVSADGAILRW 614 Score = 35.0 bits (79), Expect = 0.14 Identities = 41/168 (24%), Positives = 67/168 (39%), Gaps = 13/168 (7%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGS-----WDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 VSCV S I SG + + +W+ +L L H G + A+A SP+ Sbjct: 67 VSCVTISKEG--DYIASGQVTFMGFKADIILWDFKKRELIARLSLHKGKIEALAFSPNDL 124 Query: 191 LCAS--GGKDGVTLLWDLTE-----GKRLYSLDAGSIINSLCFSPNR-YWLCAATQDSIK 346 S G DG ++W + + G L+ G+ S+ FS R A +I+ Sbjct: 125 YLVSLGGPDDGSVVVWSIAKRDAICGSPAAGLNVGN-ATSVVFSRCRDEMFVTAGNGTIR 183 Query: 347 IWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTI 490 +W+L+ + + + P + + + D S Y G T G I Sbjct: 184 VWELDLPN--RKIWPTECQTGQMKRIVLSTGMADDDSFFYLGTTTGDI 229
>WSB1_FUGRU (Q9W5Z5) WD repeat and SOCS box-containing protein 1 (WSB-1)| Length = 427 Score = 52.4 bits (124), Expect = 9e-07 Identities = 44/169 (26%), Positives = 73/169 (43%), Gaps = 15/169 (8%) Frame = +2 Query: 41 FSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGV 220 FSP++ V S ++V +WN+ L L+GH V + SPDG+L A+ D Sbjct: 227 FSPDSSVLCSVGAS--KAVLLWNMDKYTLIRKLEGHHNDVVSCEFSPDGALLATASYDTR 284 Query: 221 TLLWDLTEGKRLYSLD----------AGSI----INSLCFSPNRYWLCAATQDS-IKIWD 355 ++WD G L L AG + S+ F + + + + D ++ W Sbjct: 285 VIVWDHQRGSILLELGHLFPPPSPIFAGGANDRWVRSVSFCADGRHIASVSDDRLVRFWS 344 Query: 356 LESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYK 502 +E + P+ S L C ++S GS L AG DG++ ++ Sbjct: 345 IEER------APQAVASLPNGL---CCAFSTTGSVLAAGTCDGSVHFWE 384 Score = 48.9 bits (115), Expect = 1e-05 Identities = 45/163 (27%), Positives = 77/163 (47%), Gaps = 13/163 (7%) Frame = +2 Query: 56 FAPT----IVSGSWDRSVKVWNLTNC-KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGV 220 FAP +VS S D+ ++VW+L + + L GH V + A SPD S+ S G Sbjct: 183 FAPDGSLMLVSASTDKKLRVWDLKDDGNMVKVLWGHPNRVYSSAFSPDSSVLCSVGASKA 242 Query: 221 TLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQDS-IKIWDLESKHIVQDL--- 385 LLW++ + + L+ + + S FSP+ L A+ D+ + +WD + I+ +L Sbjct: 243 VLLWNMDKYTLIRKLEGHHNDVVSCEFSPDGALLATASYDTRVIVWDHQRGSILLELGHL 302 Query: 386 -RPEVPV--SSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 P P+ + +S+ ADG + + D +R + I Sbjct: 303 FPPPSPIFAGGANDRWVRSVSFCADGRHIASVSDDRLVRFWSI 345 Score = 38.9 bits (89), Expect = 0.010 Identities = 26/110 (23%), Positives = 52/110 (47%), Gaps = 4/110 (3%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSL-CASGGKDGVTLLWDLTE 244 + +G + +K+W++ L L H V + +PDGSL S D +WDL + Sbjct: 148 LATGLNNGRIKIWDVYTGTLLLNLMDHTDIVRDLTFAPDGSLMLVSASTDKKLRVWDLKD 207 Query: 245 GKRLYSLDAG--SIINSLCFSPNRYWLCA-ATQDSIKIWDLESKHIVQDL 385 + + G + + S FSP+ LC+ ++ +W+++ +++ L Sbjct: 208 DGNMVKVLWGHPNRVYSSAFSPDSSVLCSVGASKAVLLWNMDKYTLIRKL 257
>PLAP_HUMAN (Q9Y263) Phospholipase A-2-activating protein (PLAP) (PLA2P)| Length = 738 Score = 52.4 bits (124), Expect = 9e-07 Identities = 32/98 (32%), Positives = 44/98 (44%) Frame = +2 Query: 65 TIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTE 244 T++SGSWD + KVW N K TL GH V AV + P+ L +G D LW Sbjct: 68 TLLSGSWDTTAKVW--LNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSADKTVKLWKAGR 125 Query: 245 GKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDL 358 +R +S + L +L A SI+ W + Sbjct: 126 CERTFS-GHEDCVRGLAILSETEFLSCANDASIRRWQI 162
>COPB2_DROME (O62621) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| Length = 914 Score = 52.0 bits (123), Expect = 1e-06 Identities = 24/69 (34%), Positives = 38/69 (55%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASG 205 V+CV + P ++SG+ DR VK+W+ N TL+GH +SAV P+ + +G Sbjct: 188 VNCVDYYHGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNISAVCFHPELPIVLTG 247 Query: 206 GKDGVTLLW 232 +DG +W Sbjct: 248 SEDGTVRIW 256 Score = 47.4 bits (111), Expect = 3e-05 Identities = 35/118 (29%), Positives = 57/118 (48%), Gaps = 4/118 (3%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAV--SPD 184 G T +V + F+P + T S S DR+VKVW L + TL+GH V+ V D Sbjct: 140 GHTHYVMQIVFNPKD-NNTFASASLDRTVKVWQLGSNFANFTLEGHEKGVNCVDYYHGGD 198 Query: 185 GSLCASGGKDGVTLLWDLTEGKRLYSLDA-GSIINSLCFSPNRYWLCAATQD-SIKIW 352 SG D + +WD + +L+ I+++CF P + ++D +++IW Sbjct: 199 KPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNISAVCFHPELPIVLTGSEDGTVRIW 256 Score = 46.2 bits (108), Expect = 6e-05 Identities = 39/165 (23%), Positives = 69/165 (41%), Gaps = 6/165 (3%) Frame = +2 Query: 23 WVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNC-KLRCTLDGHGGYVSAVAVSP-DGSLC 196 ++ C+ P P +++ S D +K+WN + +GH YV + +P D + Sbjct: 101 YLRCIAVHPTQ--PLVLTSSDDMLIKLWNWEKMWACQRVFEGHTHYVMQIVFNPKDNNTF 158 Query: 197 ASGGKDGVTLLWDLTEGKRLYSLDAGSI-INSLCF---SPNRYWLCAATQDSIKIWDLES 364 AS D +W L ++L+ +N + + Y + A +KIWD ++ Sbjct: 159 ASASLDRTVKVWQLGSNFANFTLEGHEKGVNCVDYYHGGDKPYLISGADDRLVKIWDYQN 218 Query: 365 KHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 K VQ L Q + C + + + G DGT+RI+ Sbjct: 219 KTCVQTLE-----GHAQNISAVC--FHPELPIVLTGSEDGTVRIW 256
>PK1IP_CHICK (Q5ZKU8) p21-activated protein kinase-interacting protein 1-like| (PAK1-interacting protein 1-like) Length = 369 Score = 52.0 bits (123), Expect = 1e-06 Identities = 31/144 (21%), Positives = 68/144 (47%) Frame = +2 Query: 20 GWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCA 199 G ++C+ F ++SG+ D + +WN + ++ H G+V+++++ P G L Sbjct: 76 GTITCLEFYGTAH---LLSGAEDGLICIWNTKRWECLKSIKAHKGHVTSLSIHPSGKLAL 132 Query: 200 SGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQ 379 S G D W+L EG+ + + + + +SP+ + + I+ L++ I Sbjct: 133 SVGTDKTLRTWNLVEGRSAFIKNLKQNAHIIKWSPDGEKYVTVITNKVDIYKLDTASITG 192 Query: 380 DLRPEVPVSSKQMLYCTCLSWSAD 451 + E +SS + + + L+ + D Sbjct: 193 TITIEKRISSIRFITDSVLAIAGD 216
>PLAP_MOUSE (P27612) Phospholipase A-2-activating protein (PLAP)| Length = 646 Score = 52.0 bits (123), Expect = 1e-06 Identities = 32/98 (32%), Positives = 44/98 (44%) Frame = +2 Query: 65 TIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTE 244 T++SGSWD + KVW N K TL GH V AV + P+ L +G D LW Sbjct: 68 TLLSGSWDTTAKVW--LNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSADKTIKLWKAGR 125 Query: 245 GKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDL 358 +R + L + L +L A SI+ W + Sbjct: 126 CERTF-LGHEDCVRGLAILSETEFLSCANDASIRRWQI 162
>GBB2_CAEEL (Q20636) Guanine nucleotide-binding protein beta subunit 2| Length = 356 Score = 52.0 bits (123), Expect = 1e-06 Identities = 43/167 (25%), Positives = 80/167 (47%), Gaps = 6/167 (3%) Frame = +2 Query: 17 TGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAV--SPDGS 190 T ++SC F ++ I++GS D + +W++ + +L GH G V A+ V G+ Sbjct: 156 TSYMSCCTFLRSD--NLILTGSGDSTCAIWDVESGQLIQNFHGHTGDVFAIDVPKCDTGN 213 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSI-INSLCFSPNRYWLCAATQD-SIKIWDLES 364 S G D +L+WD+ G+ + S + IN++ F PN + D + +++DL + Sbjct: 214 TFISAGADKHSLVWDIRSGQCVQSFEGHEADINTVRFHPNGDAFATGSDDATCRLFDLRA 273 Query: 365 KHIVQDLRPEVPVSSKQMLY--CTCLSWSADGSTLYAGYTDGTIRIY 499 +V V K+ + + +S G L+AGY D + ++ Sbjct: 274 DR-------QVCVYEKESILFPVNGVDFSLSGRILFAGYGDYRVGVW 313 Score = 47.8 bits (112), Expect = 2e-05 Identities = 42/167 (25%), Positives = 75/167 (44%), Gaps = 4/167 (2%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G TG V + + T +S D+ VW++ + + + +GH ++ V P+G Sbjct: 196 GHTGDVFAIDVPKCDTGNTFISAGADKHSLVWDIRSGQCVQSFEGHEADINTVRFHPNGD 255 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSI---INSLCFSPNRYWLCAATQD-SIKIWDL 358 A+G D L+DL +++ + SI +N + FS + L A D + +WD Sbjct: 256 AFATGSDDATCRLFDLRADRQVCVYEKESILFPVNGVDFSLSGRILFAGYGDYRVGVWD- 314 Query: 359 ESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 ++ R V + + +CL S DG+ + + D TIRI+ Sbjct: 315 ----SLKCARHSVLYGHENRI--SCLRTSPDGTAVCSASWDCTIRIW 355 Score = 39.3 bits (90), Expect = 0.008 Identities = 38/174 (21%), Positives = 68/174 (39%), Gaps = 10/174 (5%) Frame = +2 Query: 14 PTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTN----CKLRCTLDGHGGYVSAVAVSP 181 PT WV FSP++ I G D V L+ + + + H Y+S Sbjct: 109 PTTWVMACAFSPSS--QMIACGGLDNKCSVVPLSFEDDIIQKKRQVATHTSYMSCCTFLR 166 Query: 182 DGSLCASGGKDGVTLLWDLTEGKRLYSL-----DAGSIINSLCFSPNRYWLCAATQDSIK 346 +L +G D +WD+ G+ + + D +I C + N + A + S+ Sbjct: 167 SDNLILTGSGDSTCAIWDVESGQLIQNFHGHTGDVFAIDVPKCDTGNTFISAGADKHSL- 225 Query: 347 IWDLESKHIVQDLR-PEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 +WD+ S VQ E +++ + + +G G D T R++ + Sbjct: 226 VWDIRSGQCVQSFEGHEADINT--------VRFHPNGDAFATGSDDATCRLFDL 271 Score = 32.0 bits (71), Expect = 1.2 Identities = 30/130 (23%), Positives = 50/130 (38%), Gaps = 2/130 (1%) Frame = +2 Query: 122 KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWD-LTEGKRLYSLDAGSIINSLCF 298 K R L GH G V + S D S +DG ++WD T K + + + F Sbjct: 59 KQRRILKGHVGKVLCMDWSLDKRHIVSSSQDGKVIVWDGFTTNKEHALTMPTTWVMACAF 118 Query: 299 SPNRYWL-CAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGY 475 SP+ + C + + L + + + +V + M CT L + + G Sbjct: 119 SPSSQMIACGGLDNKCSVVPLSFEDDIIQKKRQVATHTSYMSCCTFL---RSDNLILTGS 175 Query: 476 TDGTIRIYKI 505 D T I+ + Sbjct: 176 GDSTCAIWDV 185
>WDR1_XENLA (Q9W7F2) WD-repeat protein 1 (Actin-interacting protein 1) (XAIP1)| Length = 608 Score = 52.0 bits (123), Expect = 1e-06 Identities = 41/133 (30%), Positives = 62/133 (46%), Gaps = 5/133 (3%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 +V+GS D K + T+ H +V+ V SPDGS AS G DG L+D G Sbjct: 162 LVTGSDDNCCAFLEGPPFKFKFTMSDHSRFVNCVRFSPDGSKLASAGADGQIFLYDGKTG 221 Query: 248 KRLYSLDAGSI----INSLCFSPNRYWLCAATQD-SIKIWDLESKHIVQDLRPEVPVSSK 412 +++ SL I ++ +SP+ L +A+ D + KIWD+ + V V + Sbjct: 222 EKVCSLGGSKAHDGGIYAVSWSPDGTQLLSASGDKTTKIWDVAANSAVTTFNLGSDVLDQ 281 Query: 413 QMLYCTCLSWSAD 451 Q+ CL W D Sbjct: 282 QL---GCL-WQKD 290 Score = 51.6 bits (122), Expect = 1e-06 Identities = 44/165 (26%), Positives = 73/165 (44%), Gaps = 6/165 (3%) Frame = +2 Query: 23 WVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDG---HGGYVSAVAVSPDGSL 193 +V+CVRFSP+ + S D + +++ + C+L G H G + AV+ SPDG+ Sbjct: 191 FVNCVRFSPD--GSKLASAGADGQIFLYDGKTGEKVCSLGGSKAHDGGIYAVSWSPDGTQ 248 Query: 194 CASGGKDGVTLLWDLTEGKRLYSLDAGSIINSL---CFSPNRYWLCAATQDSIKIWDLES 364 S D T +WD+ + + + GS + C Y L + I L+ Sbjct: 249 LLSASGDKTTKIWDVAANSAVTTFNLGSDVLDQQLGCLWQKDYLLSVSLSGYINY--LDK 306 Query: 365 KHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 + + LR V + + C ++ S ST+Y G DG I + Sbjct: 307 NNPARPLR--VIKGHNKSIQCMTVNNSDGRSTIYTGSHDGHINYW 349 Score = 29.6 bits (65), Expect = 6.1 Identities = 37/161 (22%), Positives = 59/161 (36%), Gaps = 7/161 (4%) Frame = +2 Query: 38 RFSPNNFAPTIVSGSWDRSVKVWNLTNCK--LRCTLDGHGGYVSAVAVSPDGSLCASGG- 208 R++P+ F I SG +++W+ T + L+ G + +A + D A G Sbjct: 65 RYAPSGFY--IASGDTSGKLRIWDTTQKEHLLKYEYQPFAGKIKDIAWTEDSKRIAVVGE 122 Query: 209 ---KDGVTLLWDLTEGKRLYSLDAG-SIINSLCFSPNRYWLCAATQDSIKIWDLESKHIV 376 K LWD G + + +INS+ R + D LE Sbjct: 123 GREKFASVFLWDT--GSSVGEITGNIKVINSVDIKQTRPYRLVTGSDDNCCAFLEGPPFK 180 Query: 377 QDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 S + C+ +S DGS L + DG I +Y Sbjct: 181 FKF-----TMSDHSRFVNCVRFSPDGSKLASAGADGQIFLY 216
>WDR16_MACFA (Q95JL5) WD-repeat protein 16| Length = 571 Score = 52.0 bits (123), Expect = 1e-06 Identities = 27/110 (24%), Positives = 52/110 (47%), Gaps = 4/110 (3%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNC---KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL 238 ++SG + V+VW + C KL L H VS + V + C + DG ++WDL Sbjct: 383 VISGGGEGEVRVWQI-GCQTQKLEEALKEHKSSVSCIRVKKNNEECVTASTDGTCIIWDL 441 Query: 239 TEGKRLYSLDAGSIINSLCFSPNRYW-LCAATQDSIKIWDLESKHIVQDL 385 +R + A ++ +C+ P + + + T I W++ ++++L Sbjct: 442 VRLRRNQMILANTLFQCVCYHPEEFQIITSGTDRKIAYWEVFDGTVIREL 491 Score = 41.6 bits (96), Expect = 0.002 Identities = 37/133 (27%), Positives = 60/133 (45%), Gaps = 10/133 (7%) Frame = +2 Query: 137 LDGHGGYVSAVAVSPDGSLCASG-----GKDGVTLLWDLTEGKRL--YSLDAGSIINSLC 295 L GHG VS +A+S G ASG G +LWD + + L SL G I +L Sbjct: 60 LQGHGNNVSCLAISRSGRYIASGQVTFMGFKADIILWDYKKRELLARLSLHKGK-IEALA 118 Query: 296 FSPNRYWLCA---ATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLY 466 FSPN +L + S+ +W + + D P + + T + +S ++ Sbjct: 119 FSPNDLYLVSLGGPDDGSVVVWSIAKR----DAICGSPAAGLNVGNATNVIFSRCRDEMF 174 Query: 467 AGYTDGTIRIYKI 505 +GTIR++++ Sbjct: 175 VTAGNGTIRVWEL 187 Score = 38.9 bits (89), Expect = 0.010 Identities = 26/110 (23%), Positives = 51/110 (46%), Gaps = 3/110 (2%) Frame = +2 Query: 32 CVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGH-GGYVSAVAVSPDGSLCASGG 208 CV + P F I++ DR + W + + + L+G G ++ + ++ +G +GG Sbjct: 458 CVCYHPEEFQ--IITSGTDRKIAYWEVFDGTVIRELEGSLSGSINGMDITQEGVHFVTGG 515 Query: 209 KDGVTLLWDLTEGKRLY-SLDAGSIINSLCFSP-NRYWLCAATQDSIKIW 352 D + +WD EG+ + + I + SP N+Y + + +I W Sbjct: 516 NDHLVKVWDYNEGEVTHVGVGHSGNITRIRISPGNQYIVSVSADGAILRW 565 Score = 36.6 bits (83), Expect = 0.050 Identities = 30/137 (21%), Positives = 55/137 (40%), Gaps = 7/137 (5%) Frame = +2 Query: 101 VWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCAS--GGKDGVTLLWDLTE-----GKRLY 259 +W+ +L L H G + A+A SP+ S G DG ++W + + G Sbjct: 95 LWDYKKRELLARLSLHKGKIEALAFSPNDLYLVSLGGPDDGSVVVWSIAKRDAICGSPAA 154 Query: 260 SLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLS 439 L+ G+ N + A +I++W+L+ + + + P + + + Sbjct: 155 GLNVGNATNVIFSRCRDEMFVTAGNGTIRVWELDLPN--RKIWPTECQTGQMKRIVMSIG 212 Query: 440 WSADGSTLYAGYTDGTI 490 + D S Y G T G I Sbjct: 213 MADDDSFFYLGTTTGDI 229
>YH92_CAEEL (Q23256) Hypothetical WD-repeat protein ZC302.2| Length = 501 Score = 52.0 bits (123), Expect = 1e-06 Identities = 49/201 (24%), Positives = 78/201 (38%), Gaps = 46/201 (22%) Frame = +2 Query: 41 FSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGV 220 FS ++ + I S S D +VK++++ + T+ GH YV + +P SL AS G D Sbjct: 261 FSWSSNSQFIASASDDTTVKIFDVISGACLRTMRGHTNYVFCCSFNPQSSLIASAGFDET 320 Query: 221 TLLWDLTEGK---------------------------------RLYSLDAGSIINSL--- 292 +WD G R++ +GS + +L Sbjct: 321 VRVWDFKTGLCVKCIPAHSDPITSISYNHDGNTMATSSYDGCIRVWDAASGSCLKTLVDT 380 Query: 293 --------CFSPN-RYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWS 445 CFSPN +Y L A S+K+WD + ++ K YC + S Sbjct: 381 DHAPVTFVCFSPNGKYLLSAQLDSSLKLWDPKKAKPLKYYN-----GHKNKKYCLFANMS 435 Query: 446 AD-GSTLYAGYTDGTIRIYKI 505 G + +G DG I ++ I Sbjct: 436 VPLGKHIISGSEDGRILVWSI 456 Score = 51.2 bits (121), Expect = 2e-06 Identities = 42/165 (25%), Positives = 78/165 (47%), Gaps = 2/165 (1%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 G T VS ++FS + +GS D+ +KVWN + TL H ++ + S + Sbjct: 211 GHTKSVSVIKFS--YCGKYLGTGSADKQIKVWNTVDMTYLQTLASHQLGINDFSWSSNSQ 268 Query: 191 LCASGGKDGVTLLWDLTEGKRLYSLDAGSIINSLC-FSPNRYWLCAATQD-SIKIWDLES 364 AS D ++D+ G L ++ + C F+P + +A D ++++WD ++ Sbjct: 269 FIASASDDTTVKIFDVISGACLRTMRGHTNYVFCCSFNPQSSLIASAGFDETVRVWDFKT 328 Query: 365 KHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 V+ +P S + T +S++ DG+T+ DG IR++ Sbjct: 329 GLCVKC----IPAHSDPI---TSISYNHDGNTMATSSYDGCIRVW 366 Score = 41.2 bits (95), Expect = 0.002 Identities = 30/124 (24%), Positives = 58/124 (46%), Gaps = 2/124 (1%) Frame = +2 Query: 134 TLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRLYSLDAGSI-INSLCFSPNR 310 T+ GH VS + S G +G D +W+ + L +L + + IN +S N Sbjct: 208 TISGHTKSVSVIKFSYCGKYLGTGSADKQIKVWNTVDMTYLQTLASHQLGINDFSWSSNS 267 Query: 311 YWLCAATQD-SIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGT 487 ++ +A+ D ++KI+D+ S ++ +R Y C S++ S + + D T Sbjct: 268 QFIASASDDTTVKIFDVISGACLRTMRGHTN-------YVFCCSFNPQSSLIASAGFDET 320 Query: 488 IRIY 499 +R++ Sbjct: 321 VRVW 324 Score = 40.0 bits (92), Expect = 0.004 Identities = 31/121 (25%), Positives = 53/121 (43%), Gaps = 7/121 (5%) Frame = +2 Query: 44 SPNNFAPTIVSGSWDRSVKVWNLTNCK-LRCTLDGHGGYVSAVAVSPDGSLCASGGKDGV 220 S N+ T+ + S+D ++VW+ + L+ +D V+ V SP+G S D Sbjct: 346 SYNHDGNTMATSSYDGCIRVWDAASGSCLKTLVDTDHAPVTFVCFSPNGKYLLSAQLDSS 405 Query: 221 TLLWDLTEGKRLYSLDAGSIINSLCFSPN------RYWLCAATQDSIKIWDLESKHIVQD 382 LWD + K L + G C N ++ + + I +W +++K IVQ Sbjct: 406 LKLWDPKKAKPLKYYN-GHKNKKYCLFANMSVPLGKHIISGSEDGRILVWSIQTKQIVQI 464 Query: 383 L 385 L Sbjct: 465 L 465 Score = 33.9 bits (76), Expect = 0.32 Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 2/57 (3%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGG--KDGVTLLW 232 I+SGS D + VW++ ++ L+GH V A P ++ ASGG D V +W Sbjct: 442 IISGSEDGRILVWSIQTKQIVQILEGHTTPVLATDSHPTLNIIASGGLEPDNVIRIW 498
>PLAP_RAT (P54319) Phospholipase A-2-activating protein (PLAP)| Length = 647 Score = 52.0 bits (123), Expect = 1e-06 Identities = 32/98 (32%), Positives = 44/98 (44%) Frame = +2 Query: 65 TIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTE 244 T++SGSWD + KVW N K TL GH V AV + P+ L +G D LW Sbjct: 68 TLLSGSWDTTAKVW--LNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSADKTIKLWKAGR 125 Query: 245 GKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDL 358 +R +S + L +L A SI+ W + Sbjct: 126 CERTFS-GHEDCVRGLAILSETEFLSCANDASIRRWQI 162
>KMHA_DICDI (P42527) Myosin heavy chain kinase A (EC 2.7.11.7) (MHCK A)| Length = 1146 Score = 52.0 bits (123), Expect = 1e-06 Identities = 42/168 (25%), Positives = 78/168 (46%), Gaps = 3/168 (1%) Frame = +2 Query: 11 GPTGWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDG-HGGYVSAVAVSPDG 187 G TG V+CV + + S S+D+++KVW+L+ K + +G H Y+ +A+S G Sbjct: 952 GHTGEVNCVVANEKY----LFSCSYDKTIKVWDLSTFKEIKSFEGVHTKYIKTLALS--G 1005 Query: 188 SLCASGGKDGVTLLWDLTEGKRLYSLDAGS--IINSLCFSPNRYWLCAATQDSIKIWDLE 361 SGG D + +WD L+++ +++ C + Y + + IKIWDL Sbjct: 1006 RYLFSGGNDQIIYVWDTETLSMLFNMQGHEDWVLSLHCTA--SYLFSTSKDNVIKIWDLS 1063 Query: 362 SKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 + + L+ + + S LY+G D +I+++ + Sbjct: 1064 NFSCIDTLKGH---------WNSVSSCVVKDRYLYSGSEDNSIKVWDL 1102 Score = 48.9 bits (115), Expect = 1e-05 Identities = 32/104 (30%), Positives = 49/104 (47%), Gaps = 1/104 (0%) Frame = +2 Query: 59 APTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL 238 A + S S D +K+W+L+N TL GH VS+ V SG +D +WDL Sbjct: 1045 ASYLFSTSKDNVIKIWDLSNFSCIDTLKGHWNSVSSCVVK--DRYLYSGSEDNSIKVWDL 1102 Query: 239 TEGKRLYSLDAGSIINSLCFSP-NRYWLCAATQDSIKIWDLESK 367 + +Y++ + C N + AA SIK+W+ +SK Sbjct: 1103 DTLECVYTIPKSHSLGVKCLMVFNNQIISAAFDGSIKVWEWQSK 1146 Score = 47.0 bits (110), Expect = 4e-05 Identities = 34/145 (23%), Positives = 65/145 (44%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEG 247 + SG D+ + VW+ + + GH +V ++ + S S KD V +WDL+ Sbjct: 1008 LFSGGNDQIIYVWDTETLSMLFNMQGHEDWVLSLHCT--ASYLFSTSKDNVIKIWDLSNF 1065 Query: 248 KRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYC 427 + +L S C +RY + +SIK+WDL++ V +P S + C Sbjct: 1066 SCIDTLKGHWNSVSSCVVKDRYLYSGSEDNSIKVWDLDTLECVY----TIPKSHSLGVKC 1121 Query: 428 TCLSWSADGSTLYAGYTDGTIRIYK 502 + + + + DG+I++++ Sbjct: 1122 LMVF----NNQIISAAFDGSIKVWE 1142
>YK16_YEAST (P36130) Hypothetical 74.7 kDa Trp-Asp repeats-containing protein| in DAL80-GAP1 intergenic region Length = 659 Score = 51.6 bits (122), Expect = 1e-06 Identities = 44/170 (25%), Positives = 73/170 (42%), Gaps = 24/170 (14%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLD-----------------GHGGYVSAVAVSPDGSL- 193 +VSGS D+ + W+LT K LD +G + G+L Sbjct: 453 LVSGSRDKKIFHWDLTTGKCIQQLDLIFTPTHSDIKMPARSLNNGACLLGTEAPMIGALQ 512 Query: 194 -----CASGGKDGVTLLWDLTEGKRLYSLDAGSI-INSLCFSPNRYWLCAATQDSIKIWD 355 A+G KDG+ LWDL GK + L+ + I SL F + + + +S++IWD Sbjct: 513 CYNSALATGTKDGIVRLWDLRVGKPVRLLEGHTDGITSLKFDSEKL-VTGSMDNSVRIWD 571 Query: 356 LESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIYKI 505 L + I+ + ++PVSS DG + G +G + ++ + Sbjct: 572 LRTSSILDVIAYDLPVSSLDF----------DGKLITVGANEGGVNVFNM 611 Score = 38.1 bits (87), Expect = 0.017 Identities = 31/113 (27%), Positives = 56/113 (49%), Gaps = 5/113 (4%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAV-SPDGSLCASGGKDGVTLLWDLTE 244 I+S ++ R N T ++ HG ++A+ +P G+LC+S +D + +WDL Sbjct: 313 IISETYSR-----NTTAFRMTIPHGEHGNSITALDFDTPWGTLCSSSYQDRIVKVWDLNH 367 Query: 245 GKRLYSLDAG-SIINSLCFSPNRY-WLCAATQD-SIKIWDLE-SKHIVQDLRP 391 G ++ L + +N + Y L ++D ++K+WDL S+ I D P Sbjct: 368 GIQVGELPGHLATVNCMQIDKKNYNMLITGSKDATLKLWDLNLSREIYLDHSP 420
>PK1IP_BOVIN (Q5EA99) p21-activated protein kinase-interacting protein 1| (PAK1-interacting protein 1) Length = 392 Score = 51.6 bits (122), Expect = 1e-06 Identities = 33/144 (22%), Positives = 67/144 (46%) Frame = +2 Query: 20 GWVSCVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCA 199 G ++C++F N ++SG+ D + VW+ + ++ H G+V+ +++ P G L Sbjct: 83 GTITCLKFHGNRH---LISGAEDGLICVWDARRWECLKSIRAHKGHVTFLSIHPSGRLAL 139 Query: 200 SGGKDGVTLLWDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIVQ 379 S G D W+L EG+ + + + + +SP + I ++ L++ + Sbjct: 140 SVGTDKTLRTWNLVEGRSAFIKNIKQSAHIVEWSPKGEKYVVVILNRIDVYQLDTASVSG 199 Query: 380 DLRPEVPVSSKQMLYCTCLSWSAD 451 + E VSS L + L+ + D Sbjct: 200 TITNERRVSSVTFLSESVLTVAGD 223
>IF32_SCHPO (P79083) Eukaryotic translation initiation factor 3 39 kDa subunit| (eIF3 p39) (Translation initiation factor eIF3, p39 subunit) (Suppressor of uncontrolled mitosis 1) Length = 328 Score = 51.6 bits (122), Expect = 1e-06 Identities = 37/156 (23%), Positives = 67/156 (42%), Gaps = 6/156 (3%) Frame = +2 Query: 50 NNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLL 229 N+ + S + D+ + VW N + T +GH G + ++ +L SG D L Sbjct: 19 NHDGDLLFSCAKDKVINVWFSHNGERLGTYEGHTGAIWTCDINKSSTLMVSGAADNTMRL 78 Query: 230 WDLTEGKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKIWDLESKHIV----QDLRPEV 397 WD+ GK+LY + + + + F+ + + A T++ + + V D E Sbjct: 79 WDVKTGKQLYKWEFPTAVKRVEFNEDDTRILAVTEERMGYAGTVTVFRVPISESDAAAET 138 Query: 398 P--VSSKQMLYCTCLSWSADGSTLYAGYTDGTIRIY 499 P V + + T WS L+ G+ DG++ Y Sbjct: 139 PLYVITTRESKATVAGWSYLSKFLFTGHEDGSVSRY 174 Score = 32.7 bits (73), Expect = 0.72 Identities = 30/131 (22%), Positives = 60/131 (45%), Gaps = 8/131 (6%) Frame = +2 Query: 137 LDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDLTEGKRL--YSLDAGSIINSLCFSPNR 310 L GH ++ + + DG L S KD V +W G+RL Y G+I + Sbjct: 6 LQGHERPLTQIKYNHDGDLLFSCAKDKVINVWFSHNGERLGTYEGHTGAIWTCDINKSST 65 Query: 311 YWLCAATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYA------G 472 + A +++++WD+++ Q + E P + K+ + ++ D + + A G Sbjct: 66 LMVSGAADNTMRLWDVKTGK--QLYKWEFPTAVKR------VEFNEDDTRILAVTEERMG 117 Query: 473 YTDGTIRIYKI 505 Y GT+ ++++ Sbjct: 118 YA-GTVTVFRV 127 Score = 30.8 bits (68), Expect = 2.7 Identities = 13/25 (52%), Positives = 18/25 (72%) Frame = +2 Query: 143 GHGGYVSAVAVSPDGSLCASGGKDG 217 GH G ++ +AV P G+ ASGG+DG Sbjct: 286 GHFGPINTIAVHPKGTGYASGGEDG 310
>WDR16_HUMAN (Q8N1V2) WD-repeat protein 16 (WD40-repeat protein up-regulated in| HCC) Length = 620 Score = 51.6 bits (122), Expect = 1e-06 Identities = 27/110 (24%), Positives = 52/110 (47%), Gaps = 4/110 (3%) Frame = +2 Query: 68 IVSGSWDRSVKVWNLTNC---KLRCTLDGHGGYVSAVAVSPDGSLCASGGKDGVTLLWDL 238 ++SG + V+VW + C KL L H VS + V + C + DG ++WDL Sbjct: 432 VISGGGEGEVRVWQI-GCQTQKLEEALKEHKSSVSCIRVKRNNEECVTASTDGTCIIWDL 490 Query: 239 TEGKRLYSLDAGSIINSLCFSPNRYW-LCAATQDSIKIWDLESKHIVQDL 385 +R + A ++ +C+ P + + + T I W++ ++++L Sbjct: 491 VRLRRNQMILANTLFQCVCYHPEEFQIITSGTDRKIAYWEVFDGTVIREL 540 Score = 42.4 bits (98), Expect = 0.001 Identities = 39/140 (27%), Positives = 62/140 (44%), Gaps = 10/140 (7%) Frame = +2 Query: 116 NCKLRCTLDGHGGYVSAVAVSPDGSLCASG-----GKDGVTLLWDLTEGKRL--YSLDAG 274 N K + L GHG VS +A+S G ASG G +LWD + L SL G Sbjct: 53 NTKEQNFLQGHGNNVSCLAISRSGEYIASGQVTFMGFKADIILWDYKNRELLARLSLHKG 112 Query: 275 SIINSLCFSPNRYWLCA---ATQDSIKIWDLESKHIVQDLRPEVPVSSKQMLYCTCLSWS 445 I +L FSPN +L + S+ +W + + D P + + T + +S Sbjct: 113 K-IEALAFSPNDLYLVSLGGPDDGSVVVWSIAKR----DAICGSPAAGLNVGNATNVIFS 167 Query: 446 ADGSTLYAGYTDGTIRIYKI 505 ++ +GTIR++++ Sbjct: 168 RCRDEMFMTAGNGTIRVWEL 187 Score = 38.9 bits (89), Expect = 0.010 Identities = 26/110 (23%), Positives = 51/110 (46%), Gaps = 3/110 (2%) Frame = +2 Query: 32 CVRFSPNNFAPTIVSGSWDRSVKVWNLTNCKLRCTLDGH-GGYVSAVAVSPDGSLCASGG 208 CV + P F I++ DR + W + + + L+G G ++ + ++ +G +GG Sbjct: 507 CVCYHPEEFQ--IITSGTDRKIAYWEVFDGTVIRELEGSLSGSINGMDITQEGVHFVTGG 564 Query: 209 KDGVTLLWDLTEGKRLY-SLDAGSIINSLCFSP-NRYWLCAATQDSIKIW 352 D + +WD EG+ + + I + SP N+Y + + +I W Sbjct: 565 NDHLVKVWDYNEGEVTHVGVGHSGNITRIRISPGNQYIVSVSADGAILRW 614 Score = 37.4 bits (85), Expect = 0.029 Identities = 38/167 (22%), Positives = 66/167 (39%), Gaps = 12/167 (7%) Frame = +2 Query: 26 VSCVRFSPNNFAPTIVSGS-----WDRSVKVWNLTNCKLRCTLDGHGGYVSAVAVSPDGS 190 VSC+ S + I SG + + +W+ N +L L H G + A+A SP+ Sbjct: 67 VSCLAISRSG--EYIASGQVTFMGFKADIILWDYKNRELLARLSLHKGKIEALAFSPNDL 124 Query: 191 LCAS--GGKDGVTLLWDLTE-----GKRLYSLDAGSIINSLCFSPNRYWLCAATQDSIKI 349 S G DG ++W + + G L+ G+ N + A +I++ Sbjct: 125 YLVSLGGPDDGSVVVWSIAKRDAICGSPAAGLNVGNATNVIFSRCRDEMFMTAGNGTIRV 184 Query: 350 WDLESKHIVQDLRPEVPVSSKQMLYCTCLSWSADGSTLYAGYTDGTI 490 W+L+ + + + P + + + D S Y G T G I Sbjct: 185 WELDLPN--RKIWPTECQTGQLKRIVMSIGVDDDDSFFYLGTTTGDI 229 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 82,701,628 Number of Sequences: 219361 Number of extensions: 1740770 Number of successful extensions: 8880 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 5961 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 7787 length of database: 80,573,946 effective HSP length: 106 effective length of database: 57,321,680 effective search space used: 4585734400 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
