ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bags34c14 |
|---|---|
| Clone Library Name | barley_pub |
>NTF4_TOBAC (Q40532) Mitogen-activated protein kinase homolog NTF4 (EC| 2.7.11.24) (P45) Length = 393 Score = 399 bits (1025), Expect = e-111 Identities = 193/204 (94%), Positives = 200/204 (98%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLH 212 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPP QR AFNDVYIAYELMDTDLH Sbjct: 90 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPPQREAFNDVYIAYELMDTDLH 149 Query: 213 QIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLAR 392 QIIRSNQ LSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLAR Sbjct: 150 QIIRSNQGLSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLAR 209 Query: 393 TTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQ 572 TSETDFMTEYVVTRWYRAPELLLNSS+YTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQ Sbjct: 210 VTSETDFMTEYVVTRWYRAPELLLNSSDYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQ 269 Query: 573 LRLLMELIGTPNEADLDFVNENAR 644 LRLLMELIGTP+EA+++F+NENA+ Sbjct: 270 LRLLMELIGTPSEAEMEFLNENAK 293
>MAPK_PEA (Q06060) Mitogen-activated protein kinase homolog D5 (EC 2.7.11.24)| Length = 394 Score = 398 bits (1023), Expect = e-111 Identities = 192/204 (94%), Positives = 199/204 (97%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLH 212 KIANAFDNKIDAKRTLREIKL+RHMDHEN+VAIRDI+PP QR FNDVYIAYELMDTDLH Sbjct: 92 KIANAFDNKIDAKRTLREIKLVRHMDHENVVAIRDIVPPPQREVFNDVYIAYELMDTDLH 151 Query: 213 QIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLAR 392 QIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLAR Sbjct: 152 QIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLAR 211 Query: 393 TTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQ 572 TSETDFMTEYVVTRWYRAPELLLNSS+YTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQ Sbjct: 212 VTSETDFMTEYVVTRWYRAPELLLNSSDYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQ 271 Query: 573 LRLLMELIGTPNEADLDFVNENAR 644 LRLLMELIGTP+EADL F+NENA+ Sbjct: 272 LRLLMELIGTPSEADLGFLNENAK 295
>MMK1_MEDSA (Q07176) Mitogen-activated protein kinase homolog MMK1 (EC| 2.7.11.24) (MAP kinase MSK7) (MAP kinase ERK1) Length = 387 Score = 397 bits (1020), Expect = e-110 Identities = 192/204 (94%), Positives = 198/204 (97%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLH 212 KIANAFDNKIDAKRTLREIKLLRHMDHEN+VAIRDI+PP QR FNDVYIAYELMDTDLH Sbjct: 85 KIANAFDNKIDAKRTLREIKLLRHMDHENVVAIRDIVPPPQREVFNDVYIAYELMDTDLH 144 Query: 213 QIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLAR 392 QIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLAR Sbjct: 145 QIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLAR 204 Query: 393 TTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQ 572 TSETDFMTEYVVTRWYRAPELLLNSS+YTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQ Sbjct: 205 VTSETDFMTEYVVTRWYRAPELLLNSSDYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQ 264 Query: 573 LRLLMELIGTPNEADLDFVNENAR 644 LRLLMELIGTP+E DL F+NENA+ Sbjct: 265 LRLLMELIGTPSEDDLGFLNENAK 288
>MPK6_ARATH (Q39026) Mitogen-activated protein kinase homolog 6 (EC 2.7.11.24)| (MAP kinase 6) (AtMPK6) Length = 395 Score = 395 bits (1016), Expect = e-110 Identities = 192/204 (94%), Positives = 199/204 (97%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLH 212 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPP R AFNDVYIAYELMDTDLH Sbjct: 93 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPPLRNAFNDVYIAYELMDTDLH 152 Query: 213 QIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLAR 392 QIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLAR Sbjct: 153 QIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLAR 212 Query: 393 TTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQ 572 TSE+DFMTEYVVTRWYRAPELLLNSS+YTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQ Sbjct: 213 VTSESDFMTEYVVTRWYRAPELLLNSSDYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQ 272 Query: 573 LRLLMELIGTPNEADLDFVNENAR 644 LRLLMELIGTP+E +L+F+NENA+ Sbjct: 273 LRLLMELIGTPSEEELEFLNENAK 296
>MPK3_ARATH (Q39023) Mitogen-activated protein kinase homolog 3 (EC 2.7.11.24)| (MAP kinase 3) (AtMPK3) Length = 370 Score = 364 bits (934), Expect = e-100 Identities = 173/205 (84%), Positives = 192/205 (93%), Gaps = 1/205 (0%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLH 212 KIANAFDN +DAKRTLREIKLLRH+DHENI+AIRD++PP R F+DVYI+ ELMDTDLH Sbjct: 68 KIANAFDNHMDAKRTLREIKLLRHLDHENIIAIRDVVPPPLRRQFSDVYISTELMDTDLH 127 Query: 213 QIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLAR 392 QIIRSNQ+LSEEHCQYFLYQ+LRGLKYIHSAN++HRDLKPSNLLLNANCDLKICDFGLAR Sbjct: 128 QIIRSNQSLSEEHCQYFLYQLLRGLKYIHSANIIHRDLKPSNLLLNANCDLKICDFGLAR 187 Query: 393 TTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQ 572 TSE DFMTEYVVTRWYRAPELLLNSS+YTAAIDVWSVGCIFMELM+RKPLFPG+DHVHQ Sbjct: 188 PTSENDFMTEYVVTRWYRAPELLLNSSDYTAAIDVWSVGCIFMELMNRKPLFPGKDHVHQ 247 Query: 573 LRLLMELIGTPNEADLDFV-NENAR 644 +RLL EL+GTP E+DL F NE+A+ Sbjct: 248 MRLLTELLGTPTESDLGFTHNEDAK 272
>NTF6_TOBAC (Q40531) Mitogen-activated protein kinase homolog NTF6 (EC| 2.7.11.24) (P43) Length = 371 Score = 340 bits (871), Expect = 3e-93 Identities = 160/205 (78%), Positives = 185/205 (90%), Gaps = 1/205 (0%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLH 212 KI NAF+N+IDAKRTLREIKLL HMDHENI+ I+DI+ P R FNDVYI YELMDTDLH Sbjct: 68 KIGNAFENRIDAKRTLREIKLLSHMDHENIIKIKDIVRPPDREEFNDVYIVYELMDTDLH 127 Query: 213 QIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLAR 392 QIIRS+QAL+++HCQYFLYQ+LRGLKY+HSANVLHRDLKPSNLLLNANCDLKICDFGLAR Sbjct: 128 QIIRSSQALTDDHCQYFLYQLLRGLKYVHSANVLHRDLKPSNLLLNANCDLKICDFGLAR 187 Query: 393 TTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQ 572 TTSE DFMTEYVVTRWYRAPELLLN +EYTAAID+WSVGCI MEL+ R+PLFPGRD+ Q Sbjct: 188 TTSEADFMTEYVVTRWYRAPELLLNCTEYTAAIDIWSVGCILMELIKREPLFPGRDYAQQ 247 Query: 573 LRLLMELIGTPNEADLDFV-NENAR 644 L L++ L+G+P ++DL F+ ++NAR Sbjct: 248 LGLIIALLGSPEDSDLGFLRSDNAR 272
>MPK4_ARATH (Q39024) Mitogen-activated protein kinase homolog 4 (EC 2.7.11.24)| (MAP kinase 4) (AtMPK4) Length = 376 Score = 339 bits (870), Expect = 4e-93 Identities = 161/205 (78%), Positives = 186/205 (90%), Gaps = 1/205 (0%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLH 212 KI NAFDN IDAKRTLREIKLL+HMDHEN++A++DII P QR FNDVYI YELMDTDLH Sbjct: 73 KIGNAFDNIIDAKRTLREIKLLKHMDHENVIAVKDIIKPPQRENFNDVYIVYELMDTDLH 132 Query: 213 QIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLAR 392 QIIRSNQ L+++HC++FLYQ+LRGLKY+HSANVLHRDLKPSNLLLNANCDLK+ DFGLAR Sbjct: 133 QIIRSNQPLTDDHCRFFLYQLLRGLKYVHSANVLHRDLKPSNLLLNANCDLKLGDFGLAR 192 Query: 393 TTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQ 572 T SETDFMTEYVVTRWYRAPELLLN SEYTAAID+WSVGCI E M R+PLFPG+D+VHQ Sbjct: 193 TKSETDFMTEYVVTRWYRAPELLLNCSEYTAAIDIWSVGCILGETMTREPLFPGKDYVHQ 252 Query: 573 LRLLMELIGTPNEADLDFV-NENAR 644 LRL+ ELIG+P+++ L F+ ++NAR Sbjct: 253 LRLITELIGSPDDSSLGFLRSDNAR 277
>MPK5_ARATH (Q39025) Mitogen-activated protein kinase homolog 5 (EC 2.7.11.24)| (MAP kinase 5) (AtMPK5) Length = 376 Score = 338 bits (867), Expect = 8e-93 Identities = 161/205 (78%), Positives = 188/205 (91%), Gaps = 1/205 (0%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLH 212 KI AFDNK+DAKRTLREIKLLRH++HEN+V I+DII P ++ F DVYI +ELMDTDLH Sbjct: 73 KIGKAFDNKVDAKRTLREIKLLRHLEHENVVVIKDIIRPPKKEDFVDVYIVFELMDTDLH 132 Query: 213 QIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLAR 392 QIIRSNQ+L+++HCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLN+NCDLKI DFGLAR Sbjct: 133 QIIRSNQSLNDDHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNSNCDLKITDFGLAR 192 Query: 393 TTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQ 572 TTSET++MTEYVVTRWYRAPELLLNSSEYT+AIDVWSVGCIF E+M R+PLFPG+D+VHQ Sbjct: 193 TTSETEYMTEYVVTRWYRAPELLLNSSEYTSAIDVWSVGCIFAEIMTREPLFPGKDYVHQ 252 Query: 573 LRLLMELIGTPNEADLDFV-NENAR 644 L+L+ ELIG+P+ A L+F+ + NAR Sbjct: 253 LKLITELIGSPDGASLEFLRSANAR 277
>MMK2_MEDSA (Q40353) Mitogen-activated protein kinase homolog MMK2 (EC| 2.7.11.24) Length = 371 Score = 337 bits (865), Expect = 1e-92 Identities = 161/205 (78%), Positives = 187/205 (91%), Gaps = 1/205 (0%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLH 212 KI NAFDN+IDAKRTLREIKLLRHMDHEN+++I+DII P Q+ FN VYI ELMDTDLH Sbjct: 67 KIGNAFDNRIDAKRTLREIKLLRHMDHENVMSIKDIIRPPQKENFNHVYIVSELMDTDLH 126 Query: 213 QIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLAR 392 QIIRSNQ ++++HC+YF+YQ+LRGLKY+HSANVLHRDLKPSNLLLNANCDLKI DFGLAR Sbjct: 127 QIIRSNQPMTDDHCRYFVYQLLRGLKYVHSANVLHRDLKPSNLLLNANCDLKIGDFGLAR 186 Query: 393 TTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQ 572 TTSETDFMTEYVVTRWYRAPELLLN S+YTAAID+WSVGCI E++ R+PLFPGRD+VHQ Sbjct: 187 TTSETDFMTEYVVTRWYRAPELLLNCSDYTAAIDIWSVGCILGEIVTRQPLFPGRDYVHQ 246 Query: 573 LRLLMELIGTPNEADLDFV-NENAR 644 LRL+ ELIG+P++A L F+ +ENAR Sbjct: 247 LRLVTELIGSPDDASLGFLRSENAR 271
>NTF3_TOBAC (Q40517) Mitogen-activated protein kinase homolog NTF3 (EC| 2.7.11.24) (P43) Length = 372 Score = 298 bits (762), Expect = 1e-80 Identities = 138/206 (66%), Positives = 174/206 (84%), Gaps = 2/206 (0%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLH 212 KI NAF+N+IDA RTLRE+KLLRH+ HEN++A++D++ P R +F DVY+ YELMDTDLH Sbjct: 62 KINNAFENRIDALRTLRELKLLRHLRHENVIALKDVMMPIHRRSFKDVYLVYELMDTDLH 121 Query: 213 QIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLAR 392 QII+S+Q LS +HCQYFL+Q+LRGLKY+HSAN+LHRDLKP NLL+NANCDLKICDFGLAR Sbjct: 122 QIIKSSQTLSNDHCQYFLFQLLRGLKYLHSANILHRDLKPGNLLINANCDLKICDFGLAR 181 Query: 393 TTSETD-FMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVH 569 T+S D FMTEYVVTRWYRAPELLL Y +IDVWSVGCIF EL+ RKP+FPG + ++ Sbjct: 182 TSSGKDQFMTEYVVTRWYRAPELLLCCDNYGTSIDVWSVGCIFAELLGRKPVFPGTECLN 241 Query: 570 QLRLLMELIGTPNEADLDFV-NENAR 644 QL+L++ ++G+ E D++F+ N AR Sbjct: 242 QLKLIINILGSQREEDIEFIDNPKAR 267
>MAPK_PETHY (Q40884) Mitogen-activated protein kinase homolog 1 (EC 2.7.11.24)| (PMEK1) Length = 384 Score = 297 bits (761), Expect = 2e-80 Identities = 137/206 (66%), Positives = 175/206 (84%), Gaps = 2/206 (0%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLH 212 KI NAF+N+IDA RTLRE+KLLRH+ HEN++A++D++ P QR +F DVY+ YELMDTDLH Sbjct: 62 KINNAFENRIDALRTLRELKLLRHLRHENVIALKDVMMPIQRRSFKDVYLVYELMDTDLH 121 Query: 213 QIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLAR 392 QII+S+Q LS +HCQYFL+Q+LRGLKY+HSAN+LHRDLKP NLL+NANCDLKICDFGLAR Sbjct: 122 QIIKSSQTLSNDHCQYFLFQLLRGLKYLHSANILHRDLKPGNLLINANCDLKICDFGLAR 181 Query: 393 TTSETD-FMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVH 569 T+S D FMTEYVVTRWYRAPELLL Y +IDVWSVGCIF +++ RKP+FPG + ++ Sbjct: 182 TSSGKDQFMTEYVVTRWYRAPELLLCCDNYGTSIDVWSVGCIFADVLGRKPVFPGTECLN 241 Query: 570 QLRLLMELIGTPNEADLDFV-NENAR 644 QL+L++ ++G+ E D++F+ N AR Sbjct: 242 QLKLIINILGSQREEDIEFIDNPKAR 267
>MPK7_ARATH (Q39027) Mitogen-activated protein kinase homolog 7 (EC 2.7.11.24)| (MAP kinase 7) (AtMPK7) Length = 368 Score = 293 bits (751), Expect = 2e-79 Identities = 135/216 (62%), Positives = 178/216 (82%), Gaps = 2/216 (0%) Frame = +3 Query: 3 RXRGSRWPSXKIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYI 182 R R KI N F+N++DA RTLRE+KLLRH+ HEN++A++D++ PA R++F DVY+ Sbjct: 52 RETNERVAIKKIHNVFENRVDALRTLRELKLLRHVRHENVIALKDVMLPANRSSFKDVYL 111 Query: 183 AYELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCD 362 YELMDTDLHQII+S+Q+LS++HC+YFL+Q+LRGLKY+HSAN+LHRDLKP NLL+NANCD Sbjct: 112 VYELMDTDLHQIIKSSQSLSDDHCKYFLFQLLRGLKYLHSANILHRDLKPGNLLVNANCD 171 Query: 363 LKICDFGLARTTSETD-FMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRK 539 LKICDFGLART+ + FMTEYVVTRWYRAPELLL Y +IDVWSVGCIF E++ RK Sbjct: 172 LKICDFGLARTSQGNEQFMTEYVVTRWYRAPELLLCCDNYGTSIDVWSVGCIFAEILGRK 231 Query: 540 PLFPGRDHVHQLRLLMELIGTPNEADLDFV-NENAR 644 P+FPG + ++QL+L++ ++G+ E+D+ F+ N AR Sbjct: 232 PIFPGTECLNQLKLIINVVGSQQESDIRFIDNPKAR 267
>MPK2_ARATH (Q39022) Mitogen-activated protein kinase homolog 2 (EC 2.7.11.24)| (MAP kinase 2) (AtMPK2) Length = 376 Score = 290 bits (741), Expect = 3e-78 Identities = 134/211 (63%), Positives = 172/211 (81%), Gaps = 1/211 (0%) Frame = +3 Query: 3 RXRGSRWPSXKIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYI 182 R R KI N F+N+IDA RTLRE+KLLRH+ HEN+VA++D++ + +F DVY+ Sbjct: 52 RESNERVAIKKIHNVFENRIDALRTLRELKLLRHLRHENVVALKDVMMANHKRSFKDVYL 111 Query: 183 AYELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCD 362 YELMDTDLHQII+S+Q LS +HCQYFL+Q+LRGLKYIHSAN+LHRDLKP NLL+NANCD Sbjct: 112 VYELMDTDLHQIIKSSQVLSNDHCQYFLFQLLRGLKYIHSANILHRDLKPGNLLVNANCD 171 Query: 363 LKICDFGLARTT-SETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRK 539 LKICDFGLART+ ++ FMTEYVVTRWYRAPELLL Y +IDVWSVGCIF EL+ RK Sbjct: 172 LKICDFGLARTSNTKGQFMTEYVVTRWYRAPELLLCCDNYGTSIDVWSVGCIFAELLGRK 231 Query: 540 PLFPGRDHVHQLRLLMELIGTPNEADLDFVN 632 P+FPG + ++Q++L++ ++G+ E DL+F++ Sbjct: 232 PVFPGTECLNQIKLIINILGSQREEDLEFID 262
>MPK1_ARATH (Q39021) Mitogen-activated protein kinase homolog 1 (EC 2.7.11.24)| (MAP kinase 1) (AtMPK1) Length = 370 Score = 287 bits (735), Expect = 2e-77 Identities = 130/201 (64%), Positives = 169/201 (84%), Gaps = 1/201 (0%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLH 212 KI N ++N+IDA RTLRE+KLLRH+ HEN++A++D++ P + +F DVY+ YELMDTDLH Sbjct: 62 KIHNVYENRIDALRTLRELKLLRHLRHENVIALKDVMMPIHKMSFKDVYLVYELMDTDLH 121 Query: 213 QIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLAR 392 QII+S+Q LS +HCQYFL+Q+LRGLKYIHSAN+LHRDLKP NLL+NANCDLKICDFGLAR Sbjct: 122 QIIKSSQVLSNDHCQYFLFQLLRGLKYIHSANILHRDLKPGNLLVNANCDLKICDFGLAR 181 Query: 393 -TTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVH 569 + ++ FMTEYVVTRWYRAPELLL Y +IDVWSVGCIF EL+ RKP+F G + ++ Sbjct: 182 ASNTKGQFMTEYVVTRWYRAPELLLCCDNYGTSIDVWSVGCIFAELLGRKPIFQGTECLN 241 Query: 570 QLRLLMELIGTPNEADLDFVN 632 QL+L++ ++G+ E DL+F++ Sbjct: 242 QLKLIVNILGSQREEDLEFID 262
>ERK1_DICDI (P42525) Extracellular signal-regulated kinase 1 (EC 2.7.11.24)| (ERK1) (MAP kinase 1) Length = 415 Score = 282 bits (721), Expect = 7e-76 Identities = 136/214 (63%), Positives = 168/214 (78%), Gaps = 3/214 (1%) Frame = +3 Query: 12 GSRWPSXKIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYE 191 G + KI+ AFDN D KRTLREI LLRH HEN+++I+DI+ P + F DVYI E Sbjct: 54 GEKVAIKKISKAFDNLKDTKRTLREIHLLRHFKHENLISIKDILKPNSKEQFEDVYIVSE 113 Query: 192 LMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKI 371 LMDTDLHQII S Q LS++HCQYF+YQ+LRGLK+IHSANVLHRDLKPSNLL+N +C LKI Sbjct: 114 LMDTDLHQIITSPQPLSDDHCQYFVYQMLRGLKHIHSANVLHRDLKPSNLLINEDCLLKI 173 Query: 372 CDFGLARTTSET--DFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPL 545 CD GLAR T FMTEYV TRWYRAPE++L+ ++YT AID+WSVGCIF EL+ RKPL Sbjct: 174 CDLGLARVEDATHQGFMTEYVATRWYRAPEVILSWNKYTKAIDIWSVGCIFAELLGRKPL 233 Query: 546 FPGRDHVHQLRLLMELIGTPNEADL-DFVNENAR 644 F G+D++HQ+ L++E IG+P+E D+ + NE AR Sbjct: 234 FQGKDYIHQITLIIETIGSPSEEDICNIANEQAR 267
>CPK1_CRYNE (Q8NK05) Mitogen-activated protein kinase CPK1 (EC 2.7.11.24)| (Stress-activated protein kinase CPK1) Length = 366 Score = 262 bits (669), Expect = 7e-70 Identities = 125/201 (62%), Positives = 159/201 (79%), Gaps = 9/201 (4%) Frame = +3 Query: 48 FDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRS 227 FD+ + +RTLREIKLLRH HENI++I D+I P FN+VY+ ELM+TDLH++IRS Sbjct: 50 FDHTMFCQRTLREIKLLRHFHHENIISILDLIQPESYEVFNEVYLVQELMETDLHRVIRS 109 Query: 228 NQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTSE- 404 Q LS++HCQYF+YQ LRGLK +HSA+VLHRDLKPSNLLLNANCDLKICDFGLAR++++ Sbjct: 110 -QELSDDHCQYFVYQTLRGLKALHSADVLHRDLKPSNLLLNANCDLKICDFGLARSSAKP 168 Query: 405 --------TDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRD 560 FMTEYV TRWYRAPE++L+ EYT AID+WSVGCI E+++ KPLFPGRD Sbjct: 169 PPGTSDGGQGFMTEYVATRWYRAPEVMLSFQEYTKAIDLWSVGCILAEMINGKPLFPGRD 228 Query: 561 HVHQLRLLMELIGTPNEADLD 623 + HQL L+++++GTP D + Sbjct: 229 YHHQLSLILQVLGTPTMDDFN 249
>MAPK_FUSSO (Q00859) Mitogen-activated protein kinase (EC 2.7.11.24) (FsMAPK)| Length = 355 Score = 254 bits (649), Expect = 2e-67 Identities = 120/194 (61%), Positives = 153/194 (78%), Gaps = 4/194 (2%) Frame = +3 Query: 48 FDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRS 227 FD+ + RTLRE+KLLR+ +HENI++I DI P +FN+VY+ ELM+TD+H+ IR+ Sbjct: 57 FDHSMFCLRTLREMKLLRYFNHENIISILDIQKPRNYESFNEVYLIQELMETDMHRAIRT 116 Query: 228 NQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTSET 407 Q LS++HCQYF+YQ LR LK +HSANVLHRDLKPSNLLLNANCDLK+CDFGLAR+ + Sbjct: 117 -QDLSDDHCQYFIYQTLRALKAMHSANVLHRDLKPSNLLLNANCDLKVCDFGLARSAASQ 175 Query: 408 D----FMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQL 575 + FMTEYV TRWYRAPE++L EYT AIDVWSVGCI E++ KPLFPG+D+ HQL Sbjct: 176 EDNSGFMTEYVATRWYRAPEIMLTFKEYTKAIDVWSVGCILAEMLSGKPLFPGKDYHHQL 235 Query: 576 RLLMELIGTPNEAD 617 L+++++GTP D Sbjct: 236 TLILDVLGTPTMED 249
>MK07_HUMAN (Q13164) Mitogen-activated protein kinase 7 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase) Length = 815 Score = 253 bits (645), Expect = 4e-67 Identities = 126/215 (58%), Positives = 164/215 (76%), Gaps = 6/215 (2%) Frame = +3 Query: 3 RXRGSRWPSXKIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDII-PPAQRTAFNDVY 179 R G + KI NAFD +AKRTLRE+K+L+H H+NI+AI+DI+ P F VY Sbjct: 74 RLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDILRPTVPYGEFKSVY 133 Query: 180 IAYELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANC 359 + +LM++DLHQII S+Q L+ EH +YFLYQ+LRGLKY+HSA V+HRDLKPSNLL+N NC Sbjct: 134 VVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENC 193 Query: 360 DLKICDFGLAR--TTSETD---FMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFME 524 +LKI DFG+AR TS + FMTEYV TRWYRAPEL+L+ EYT AID+WSVGCIF E Sbjct: 194 ELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGE 253 Query: 525 LMDRKPLFPGRDHVHQLRLLMELIGTPNEADLDFV 629 ++ R+ LFPG+++VHQL+L+M ++GTP+ A + V Sbjct: 254 MLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAV 288
>MK07_MOUSE (Q9WVS8) Mitogen-activated protein kinase 7 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase) Length = 806 Score = 253 bits (645), Expect = 4e-67 Identities = 126/215 (58%), Positives = 164/215 (76%), Gaps = 6/215 (2%) Frame = +3 Query: 3 RXRGSRWPSXKIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTA-FNDVY 179 R G + KI NAFD +AKRTLRE+K+L+H H+NI+AI+DI+ P F VY Sbjct: 75 RLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDILKPTVPYGEFRSVY 134 Query: 180 IAYELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANC 359 + +LM++DLHQII S+Q L+ EH +YFLYQ+LRGLKY+HSA V+HRDLKPSNLL+N NC Sbjct: 135 VVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENC 194 Query: 360 DLKICDFGLAR--TTSETD---FMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFME 524 +LKI DFG+AR TS + FMTEYV TRWYRAPEL+L+ EYT AID+WSVGCIF E Sbjct: 195 ELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGE 254 Query: 525 LMDRKPLFPGRDHVHQLRLLMELIGTPNEADLDFV 629 ++ R+ LFPG+++VHQL+L+M ++GTP+ A + V Sbjct: 255 MLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAV 289
>ERK1_CANAL (P28869) Extracellular signal-regulated kinase 1 (EC 2.7.11.24)| (ERK1) (MAP kinase 1) (MAPK 1) Length = 417 Score = 248 bits (634), Expect = 8e-66 Identities = 119/194 (61%), Positives = 152/194 (78%), Gaps = 4/194 (2%) Frame = +3 Query: 48 FDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRS 227 F+ + RTLRE+KLL+H +HENI++I I P +FN++Y+ ELM+TDLH++IR+ Sbjct: 102 FERSMLCLRTLRELKLLKHFNHENIISILAIQRPINYESFNEIYLIQELMETDLHRVIRT 161 Query: 228 NQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTSET 407 Q LS++H QYF+YQ LR LK +HSANVLHRDLKPSNLLLN+NCDLKICDFGLAR+ + Sbjct: 162 -QNLSDDHIQYFIYQTLRALKAMHSANVLHRDLKPSNLLLNSNCDLKICDFGLARSIASQ 220 Query: 408 D----FMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQL 575 + FMTEYV TRWYRAPE++L EYT AIDVWSVGCI E++ +PLFPGRD+ +QL Sbjct: 221 EDNYGFMTEYVATRWYRAPEIMLTFQEYTTAIDVWSVGCILAEMLSGRPLFPGRDYHNQL 280 Query: 576 RLLMELIGTPNEAD 617 L+ME++GTPN D Sbjct: 281 WLIMEVLGTPNMED 294
>SPK1_SCHPO (P27638) Mitogen-activated protein kinase spk1 (EC 2.7.11.24) (MAP| kinase spk1) (MAPK) Length = 372 Score = 244 bits (622), Expect = 2e-64 Identities = 117/199 (58%), Positives = 150/199 (75%), Gaps = 4/199 (2%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLH 212 K + F++ + RTLREIKLLRH HENI++I DI+PP DVYI ELM+TDL+ Sbjct: 68 KKIHPFNHPVFCLRTLREIKLLRHFRHENIISILDILPPPSYQELEDVYIVQELMETDLY 127 Query: 213 QIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLAR 392 ++IRS Q LS++HCQYF YQILR LK +HSA V+HRDLKPSNLLLNANCDLK+ DFGLAR Sbjct: 128 RVIRS-QPLSDDHCQYFTYQILRALKAMHSAGVVHRDLKPSNLLLNANCDLKVADFGLAR 186 Query: 393 TTS----ETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRD 560 +T+ FMTEYV TRWYRAPE++L+ EY+ AID+WS GCI E++ +PLFPG+D Sbjct: 187 STTAQGGNPGFMTEYVATRWYRAPEIMLSFREYSKAIDLWSTGCILAEMLSARPLFPGKD 246 Query: 561 HVHQLRLLMELIGTPNEAD 617 + Q+ L++ ++GTP D Sbjct: 247 YHSQITLILNILGTPTMDD 265
>SUR1_CAEEL (P39745) Mitogen-activated protein kinase mpk-1 (EC 2.7.11.24) (MAP| kinase sur-1) Length = 444 Score = 241 bits (615), Expect = 1e-63 Identities = 118/209 (56%), Positives = 155/209 (74%), Gaps = 5/209 (2%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLH 212 K + F+++ +RTLREIK+L HENI+ I++II + D+YI LM+TDL+ Sbjct: 125 KKISPFEHQTFCQRTLREIKILNRFKHENIINIQEIIRSETVDSLKDIYIVQCLMETDLY 184 Query: 213 QIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLAR 392 +++++ Q LS +H YFLYQILRGLKYIHSANVLHRDLKPSNLLLN CDLKICDFGLAR Sbjct: 185 KLLKT-QKLSNDHVCYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLAR 243 Query: 393 TTS----ETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRD 560 T T F+TEYV TRWYRAPE++LNS YT +IDVWSVGCI E++ +PLFPG+ Sbjct: 244 VTDPQTDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDVWSVGCILAEMLSNRPLFPGKH 303 Query: 561 HVHQLRLLMELIGTPNEADLD-FVNENAR 644 ++ QL L++ ++G+P+ ADL +N+ AR Sbjct: 304 YLDQLNLILAVVGSPSNADLQCIINDKAR 332
>MK03_HUMAN (P27361) Mitogen-activated protein kinase 3 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase 1) (MAPK 1) (p44-ERK1) (ERT2) (p44-MAPK) (Microtubule-associated protein 2 kinase) Length = 379 Score = 238 bits (607), Expect = 1e-62 Identities = 114/209 (54%), Positives = 155/209 (74%), Gaps = 5/209 (2%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLH 212 K + F+++ +RTLREI++L HEN++ IRDI+ + A DVYI +LM+TDL+ Sbjct: 71 KKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYIVQDLMETDLY 130 Query: 213 QIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLAR 392 ++++S Q LS +H YFLYQILRGLKYIHSANVLHRDLKPSNLL+N CDLKICDFGLAR Sbjct: 131 KLLKSQQ-LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLAR 189 Query: 393 TT----SETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRD 560 T F+TEYV TRWYRAPE++LNS YT +ID+WSVGCI E++ +P+FPG+ Sbjct: 190 IADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKH 249 Query: 561 HVHQLRLLMELIGTPNEADLD-FVNENAR 644 ++ QL ++ ++G+P++ DL+ +N AR Sbjct: 250 YLDQLNHILGILGSPSQEDLNCIINMKAR 278
>MK03_MOUSE (Q63844) Mitogen-activated protein kinase 3 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase 1) (MAPK 1) (p44-ERK1) (ERT2) (p44-MAPK) (Microtubule-associated protein 2 kinase) (MNK1) Length = 380 Score = 237 bits (605), Expect = 2e-62 Identities = 114/209 (54%), Positives = 154/209 (73%), Gaps = 5/209 (2%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLH 212 K + F+++ +RTLREI++L HEN++ IRDI+ A DVYI +LM+TDL+ Sbjct: 72 KKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRAPTLEAMRDVYIVQDLMETDLY 131 Query: 213 QIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLAR 392 ++++S Q LS +H YFLYQILRGLKYIHSANVLHRDLKPSNLL+N CDLKICDFGLAR Sbjct: 132 KLLKSQQ-LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLAR 190 Query: 393 TT----SETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRD 560 T F+TEYV TRWYRAPE++LNS YT +ID+WSVGCI E++ +P+FPG+ Sbjct: 191 IADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKH 250 Query: 561 HVHQLRLLMELIGTPNEADLD-FVNENAR 644 ++ QL ++ ++G+P++ DL+ +N AR Sbjct: 251 YLDQLNHILGILGSPSQEDLNCIINMKAR 279
>MK03_RAT (P21708) Mitogen-activated protein kinase 3 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase 1) (MAPK 1) (p44-ERK1) (ERT2) (p44-MAPK) (Microtubule-associated protein 2 kinase) (MNK1) Length = 380 Score = 236 bits (603), Expect = 3e-62 Identities = 114/209 (54%), Positives = 154/209 (73%), Gaps = 5/209 (2%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLH 212 K + F+++ +RTLREI++L HEN++ IRDI+ A DVYI +LM+TDL+ Sbjct: 72 KKISPFEHQTYCQRTLREIQILLGFRHENVIGIRDILRAPTLEAMRDVYIVQDLMETDLY 131 Query: 213 QIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLAR 392 ++++S Q LS +H YFLYQILRGLKYIHSANVLHRDLKPSNLL+N CDLKICDFGLAR Sbjct: 132 KLLKSQQ-LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLAR 190 Query: 393 TT----SETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRD 560 T F+TEYV TRWYRAPE++LNS YT +ID+WSVGCI E++ +P+FPG+ Sbjct: 191 IADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKH 250 Query: 561 HVHQLRLLMELIGTPNEADLD-FVNENAR 644 ++ QL ++ ++G+P++ DL+ +N AR Sbjct: 251 YLDQLNHILGILGSPSQEDLNCIINMKAR 279
>MK01_XENLA (P26696) Mitogen-activated protein kinase 1 (EC 2.7.11.24) (Myelin| xP42 protein kinase) (Myelin basic protein kinase) (MBP kinase) (M phase MAP kinase) Length = 361 Score = 235 bits (599), Expect = 1e-61 Identities = 115/209 (55%), Positives = 152/209 (72%), Gaps = 5/209 (2%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLH 212 K + F+++ +RTLREIK+L HENI+ I DII DVYI +LM+TDL+ Sbjct: 57 KKISPFEHQTYCQRTLREIKILLRFKHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLY 116 Query: 213 QIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLAR 392 +++++ Q LS +H YFLYQILRGLKYIHSANVLHRDLKPSNLLLN CDLKICDFGLAR Sbjct: 117 KLLKT-QHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLAR 175 Query: 393 TT----SETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRD 560 T F+TEYV TRWYRAPE++LNS YT +ID+WSVGCI E++ +P+FPG+ Sbjct: 176 VADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKH 235 Query: 561 HVHQLRLLMELIGTPNEADLD-FVNENAR 644 ++ QL ++ ++G+P++ DL+ +N AR Sbjct: 236 YLDQLNHILGILGSPSQEDLNCIINLKAR 264
>MK01_RAT (P63086) Mitogen-activated protein kinase 1 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 2) (ERK-2) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) (p42-MAPK) (ERT1) Length = 357 Score = 234 bits (598), Expect = 1e-61 Identities = 115/209 (55%), Positives = 152/209 (72%), Gaps = 5/209 (2%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLH 212 K + F+++ +RTLREIK+L HENI+ I DII DVYI +LM+TDL+ Sbjct: 51 KKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLY 110 Query: 213 QIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLAR 392 +++++ Q LS +H YFLYQILRGLKYIHSANVLHRDLKPSNLLLN CDLKICDFGLAR Sbjct: 111 KLLKT-QHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLAR 169 Query: 393 TT----SETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRD 560 T F+TEYV TRWYRAPE++LNS YT +ID+WSVGCI E++ +P+FPG+ Sbjct: 170 VADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKH 229 Query: 561 HVHQLRLLMELIGTPNEADLD-FVNENAR 644 ++ QL ++ ++G+P++ DL+ +N AR Sbjct: 230 YLDQLNHILGILGSPSQEDLNCIINLKAR 258
>MK01_MOUSE (P63085) Mitogen-activated protein kinase 1 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 2) (ERK-2) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) (p42-MAPK) (ERT1) Length = 357 Score = 234 bits (598), Expect = 1e-61 Identities = 115/209 (55%), Positives = 152/209 (72%), Gaps = 5/209 (2%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLH 212 K + F+++ +RTLREIK+L HENI+ I DII DVYI +LM+TDL+ Sbjct: 51 KKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLY 110 Query: 213 QIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLAR 392 +++++ Q LS +H YFLYQILRGLKYIHSANVLHRDLKPSNLLLN CDLKICDFGLAR Sbjct: 111 KLLKT-QHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLAR 169 Query: 393 TT----SETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRD 560 T F+TEYV TRWYRAPE++LNS YT +ID+WSVGCI E++ +P+FPG+ Sbjct: 170 VADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKH 229 Query: 561 HVHQLRLLMELIGTPNEADLD-FVNENAR 644 ++ QL ++ ++G+P++ DL+ +N AR Sbjct: 230 YLDQLNHILGILGSPSQEDLNCIINLKAR 258
>MK01_HUMAN (P28482) Mitogen-activated protein kinase 1 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 2) (ERK-2) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) (p42-MAPK) (ERT1) Length = 359 Score = 234 bits (598), Expect = 1e-61 Identities = 115/209 (55%), Positives = 152/209 (72%), Gaps = 5/209 (2%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLH 212 K + F+++ +RTLREIK+L HENI+ I DII DVYI +LM+TDL+ Sbjct: 53 KKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLY 112 Query: 213 QIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLAR 392 +++++ Q LS +H YFLYQILRGLKYIHSANVLHRDLKPSNLLLN CDLKICDFGLAR Sbjct: 113 KLLKT-QHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLAR 171 Query: 393 TT----SETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRD 560 T F+TEYV TRWYRAPE++LNS YT +ID+WSVGCI E++ +P+FPG+ Sbjct: 172 VADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKH 231 Query: 561 HVHQLRLLMELIGTPNEADLD-FVNENAR 644 ++ QL ++ ++G+P++ DL+ +N AR Sbjct: 232 YLDQLNHILGILGSPSQEDLNCIINLKAR 260
>MK01_BOVIN (P46196) Mitogen-activated protein kinase 1 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 2) (ERK-2) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) (p42-MAPK) (ERT1) Length = 359 Score = 234 bits (598), Expect = 1e-61 Identities = 115/209 (55%), Positives = 152/209 (72%), Gaps = 5/209 (2%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLH 212 K + F+++ +RTLREIK+L HENI+ I DII DVYI +LM+TDL+ Sbjct: 53 KKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLY 112 Query: 213 QIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLAR 392 +++++ Q LS +H YFLYQILRGLKYIHSANVLHRDLKPSNLLLN CDLKICDFGLAR Sbjct: 113 KLLKT-QHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLAR 171 Query: 393 TT----SETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRD 560 T F+TEYV TRWYRAPE++LNS YT +ID+WSVGCI E++ +P+FPG+ Sbjct: 172 VADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKH 231 Query: 561 HVHQLRLLMELIGTPNEADLD-FVNENAR 644 ++ QL ++ ++G+P++ DL+ +N AR Sbjct: 232 YLDQLNHILGILGSPSQEDLNCIINLKAR 260
>FUS3_YEAST (P16892) Mitogen-activated protein kinase FUS3 (EC 2.7.11.24) (MAP| kinase FUS3) Length = 353 Score = 232 bits (592), Expect = 6e-61 Identities = 113/198 (57%), Positives = 144/198 (72%), Gaps = 11/198 (5%) Frame = +3 Query: 48 FDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRS 227 FD + A RTLREIK+L+H HENI+ I +I P FN+VYI ELM TDLH++I S Sbjct: 47 FDKPLFALRTLREIKILKHFKHENIITIFNIQRPDSFENFNEVYIIQELMQTDLHRVI-S 105 Query: 228 NQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLART---- 395 Q LS++H QYF+YQ LR +K +H +NV+HRDLKPSNLL+N+NCDLK+CDFGLAR Sbjct: 106 TQMLSDDHIQYFIYQTLRAVKVLHGSNVIHRDLKPSNLLINSNCDLKVCDFGLARIIDES 165 Query: 396 -------TSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPG 554 T + MTEYV TRWYRAPE++L S++Y+ A+DVWS GCI EL R+P+FPG Sbjct: 166 AADNSEPTGQQSGMTEYVATRWYRAPEVMLTSAKYSRAMDVWSCGCILAELFLRRPIFPG 225 Query: 555 RDHVHQLRLLMELIGTPN 608 RD+ HQL L+ +IGTP+ Sbjct: 226 RDYRHQLLLIFGIIGTPH 243
>ERKA_DROME (P40417) Mitogen-activated protein kinase ERK-A (EC 2.7.11.24)| (Extracellular-regulated kinase A) (Protein rolled) Length = 376 Score = 232 bits (592), Expect = 6e-61 Identities = 115/209 (55%), Positives = 151/209 (72%), Gaps = 5/209 (2%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLH 212 K + F+++ +RTLREI +L HENI+ IRDI+ DVYI LM+TDL+ Sbjct: 67 KKISPFEHQTYCQRTLREITILTRFKHENIIDIRDILRVDSIDQMRDVYIVQCLMETDLY 126 Query: 213 QIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLAR 392 +++++ Q LS +H YFLYQILRGLKYIHSANVLHRDLKPSNLLLN CDLKICDFGLAR Sbjct: 127 KLLKT-QRLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNKTCDLKICDFGLAR 185 Query: 393 TT----SETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRD 560 T F+TEYV TRWYRAPE++LNS YT +ID+WSVGCI E++ +P+FPG+ Sbjct: 186 IADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKH 245 Query: 561 HVHQLRLLMELIGTPNEADLD-FVNENAR 644 ++ QL ++ ++G+P+ DL+ +NE AR Sbjct: 246 YLDQLNHILGVLGSPSRDDLECIINEKAR 274
>MKC1_CANAL (P43068) Mitogen-activated protein kinase MKC1 (EC 2.7.11.24) (MAP| kinase MKC1) Length = 501 Score = 229 bits (585), Expect = 4e-60 Identities = 116/210 (55%), Positives = 149/210 (70%), Gaps = 8/210 (3%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHM-DHENIVAIRD--IIPPAQRTAFNDVYIAYELMDT 203 KI N F I KR LRE+KLL+ H+NI + D IIP FN++Y+ ELM+ Sbjct: 75 KITNIFSKNILCKRALRELKLLQFFRGHKNITCLYDLDIIPNPMTGEFNEIYLYEELMEC 134 Query: 204 DLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFG 383 D+HQIIRS Q LS++H Q F+YQ+L GL +IHSA+VLHRDLKP NLL+NA+C+LKICDFG Sbjct: 135 DMHQIIRSGQPLSDQHYQSFIYQVLCGLNFIHSADVLHRDLKPGNLLVNADCELKICDFG 194 Query: 384 LARTTSE-----TDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLF 548 LAR SE FMTEYV TRWYRAPE++L+ + YT AID+WSVGCI EL+ KPLF Sbjct: 195 LARGFSENPDENAGFMTEYVATRWYRAPEIMLSFTNYTKAIDIWSVGCILAELLGGKPLF 254 Query: 549 PGRDHVHQLRLLMELIGTPNEADLDFVNEN 638 G+D+V QL ++ ++GTP E+ L + + Sbjct: 255 RGKDYVDQLNQILMILGTPPESTLQRIGSH 284
>SPM1_SCHPO (Q92398) Mitogen-activated protein kinase spm1 (EC 2.7.11.24) (MAP| kinase spm1) (MAP kinase pmk1) Length = 422 Score = 229 bits (585), Expect = 4e-60 Identities = 122/210 (58%), Positives = 146/210 (69%), Gaps = 8/210 (3%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHM-DHENIVAIRD--IIPPAQRTAFNDVYIAYELMDT 203 KI N F I KR LREIKLL H +H NI I D II P FN+VYI ELM+ Sbjct: 53 KITNVFSKSILTKRALREIKLLIHFRNHRNITCIYDLDIINPYN---FNEVYIYEELMEA 109 Query: 204 DLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFG 383 DL+ II+S Q L++ H Q F+YQIL GLKYIHSANV+HRDLKP NLL+NA+C+LKICDFG Sbjct: 110 DLNAIIKSGQPLTDAHFQSFIYQILCGLKYIHSANVIHRDLKPGNLLVNADCELKICDFG 169 Query: 384 LARTTSET-----DFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLF 548 LAR SE FMTEYV TRWYRAPE++L+ S Y IDVWSVGCI EL+ PLF Sbjct: 170 LARGCSENPEENPGFMTEYVATRWYRAPEIMLSFSSYHKGIDVWSVGCILAELLGGTPLF 229 Query: 549 PGRDHVHQLRLLMELIGTPNEADLDFVNEN 638 G+D VHQL L++ +GTP+E L ++ + Sbjct: 230 KGKDFVHQLNLILHQLGTPDEETLSHISSS 259
>KSS1_YEAST (P14681) Mitogen-activated protein kinase KSS1 (EC 2.7.11.24) (MAP| kinase KSS1) (Kinase suppressor of SST2) Length = 368 Score = 229 bits (584), Expect = 5e-60 Identities = 112/205 (54%), Positives = 146/205 (71%), Gaps = 13/205 (6%) Frame = +3 Query: 48 FDNKIDAKRTLREIKLLRHM-DHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIR 224 F K+ RT+REIKLLR+ +HENI++I D + P N VY+ ELM+TDL ++I Sbjct: 47 FSKKLFVTRTIREIKLLRYFHEHENIISILDKVRPVSIDKLNAVYLVEELMETDLQKVIN 106 Query: 225 SNQA----LSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLAR 392 + + LS++H QYF YQILR LK IHSA V+HRD+KPSNLLLN+NCDLK+CDFGLAR Sbjct: 107 NQNSGFSTLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFGLAR 166 Query: 393 TTSETD--------FMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLF 548 + + FMTEYV TRWYRAPE++L EYT A+D+WS GCI E++ KPLF Sbjct: 167 CLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVSGKPLF 226 Query: 549 PGRDHVHQLRLLMELIGTPNEADLD 623 PGRD+ HQL L++E++GTP+ D + Sbjct: 227 PGRDYHHQLWLILEVLGTPSFEDFN 251
>MK14A_DROME (O62618) Mitogen-activated protein kinase 14A (EC 2.7.11.24) (MAP| kinase p38a) (p38 MAPK) (Dp38) (D-p38a) Length = 366 Score = 228 bits (582), Expect = 9e-60 Identities = 109/195 (55%), Positives = 140/195 (71%), Gaps = 4/195 (2%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTA----FNDVYIAYELMD 200 K+A F + + AKRT RE++LL+HMDHEN++ + DI P F VY+ LMD Sbjct: 55 KLARPFQSAVHAKRTYRELRLLKHMDHENVIGLLDIFHPHPANGSLENFQQVYLVTHLMD 114 Query: 201 TDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDF 380 DL+ IIR Q LS++H Q+ +YQILRGLKYIHSA V+HRDLKPSN+ +N +C+L+I DF Sbjct: 115 ADLNNIIRM-QHLSDDHVQFLVYQILRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDF 173 Query: 381 GLARTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRD 560 GLAR T MT YV TRWYRAPE++LN Y +D+WSVGCI EL+ R+ LFPG D Sbjct: 174 GLARPTENE--MTGYVATRWYRAPEIMLNWMHYDQTVDIWSVGCIMAELITRRTLFPGTD 231 Query: 561 HVHQLRLLMELIGTP 605 H+HQL L+ME++GTP Sbjct: 232 HIHQLNLIMEMLGTP 246
>MK14B_DROME (O61443) Mitogen-activated protein kinase 14B (EC 2.7.11.24) (MAP| kinase p38b) (D-p38b) Length = 365 Score = 226 bits (576), Expect = 4e-59 Identities = 110/209 (52%), Positives = 147/209 (70%), Gaps = 5/209 (2%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRT----AFNDVYIAYELMD 200 K+A F + + AKRT RE++LL+HMDHEN++ + D+ P Q F VY+ LMD Sbjct: 54 KLARPFQSAVHAKRTYRELRLLKHMDHENVIGLLDVFHPGQPADSLDQFQQVYMVTHLMD 113 Query: 201 TDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDF 380 DL+ IIR+ Q LS++H Q+ +YQILRGLKYIHSA V+HRDLKPSN+ +N +C+L+I DF Sbjct: 114 ADLNNIIRT-QKLSDDHVQFLVYQILRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDF 172 Query: 381 GLARTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRD 560 GLAR MT YV TRWYRAPE++LN Y D+WSVGCI EL+ + LFPG D Sbjct: 173 GLARPAESE--MTGYVATRWYRAPEIMLNWMHYNQTADIWSVGCIMAELLTGRTLFPGTD 230 Query: 561 HVHQLRLLMELIGTPNEADLDFV-NENAR 644 H+HQL L+ME++GTP + + + +E+AR Sbjct: 231 HIHQLNLIMEVLGTPADEFMSRISSESAR 259
>MK14_RAT (P70618) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (CRK1) Length = 359 Score = 226 bits (575), Expect = 6e-59 Identities = 111/213 (52%), Positives = 151/213 (70%), Gaps = 2/213 (0%) Frame = +3 Query: 12 GSRWPSXKIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTA-FNDVYIAY 188 G R K++ F + I AKRT RE++LL+HM HEN++ + D+ PA+ FNDVY+ Sbjct: 46 GHRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVT 105 Query: 189 ELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLK 368 LM DL+ I++ Q L+++H Q+ +YQILRGLKYIHSA+++HRDLKPSNL +N +C+LK Sbjct: 106 HLMGADLNNIVKC-QKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELK 164 Query: 369 ICDFGLARTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLF 548 I DFGLAR T D MT YV TRWYRAPE++LN Y +D+WSVGCI EL+ + LF Sbjct: 165 ILDFGLARHTD--DEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLF 222 Query: 549 PGRDHVHQLRLLMELIGTPNEADLDFV-NENAR 644 PG DH+ QL+L++ L+GTP L + +E+AR Sbjct: 223 PGTDHIDQLKLILRLVGTPGAELLKKISSESAR 255
>MK14_MOUSE (P47811) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (CRK1) Length = 359 Score = 226 bits (575), Expect = 6e-59 Identities = 111/213 (52%), Positives = 151/213 (70%), Gaps = 2/213 (0%) Frame = +3 Query: 12 GSRWPSXKIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTA-FNDVYIAY 188 G R K++ F + I AKRT RE++LL+HM HEN++ + D+ PA+ FNDVY+ Sbjct: 46 GHRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVT 105 Query: 189 ELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLK 368 LM DL+ I++ Q L+++H Q+ +YQILRGLKYIHSA+++HRDLKPSNL +N +C+LK Sbjct: 106 HLMGADLNNIVKC-QKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELK 164 Query: 369 ICDFGLARTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLF 548 I DFGLAR T D MT YV TRWYRAPE++LN Y +D+WSVGCI EL+ + LF Sbjct: 165 ILDFGLARHTD--DEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLF 222 Query: 549 PGRDHVHQLRLLMELIGTPNEADLDFV-NENAR 644 PG DH+ QL+L++ L+GTP L + +E+AR Sbjct: 223 PGTDHIDQLKLILRLVGTPGAELLKKISSESAR 255
>MK14_CANFA (O02812) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) Length = 359 Score = 226 bits (575), Expect = 6e-59 Identities = 110/204 (53%), Positives = 147/204 (72%), Gaps = 1/204 (0%) Frame = +3 Query: 12 GSRWPSXKIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTA-FNDVYIAY 188 G R K++ F + I AKRT RE++LL+HM HEN++ + D+ PA+ FNDVY+ Sbjct: 46 GLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVT 105 Query: 189 ELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLK 368 LM DL+ I++ Q L+++H Q+ +YQILRGLKYIHSA+++HRDLKPSNL +N +C+LK Sbjct: 106 HLMGADLNNIVKC-QKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELK 164 Query: 369 ICDFGLARTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLF 548 I DFGLAR T D MT YV TRWYRAPE++LN Y +D+WSVGCI EL+ + LF Sbjct: 165 ILDFGLARHTD--DEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLF 222 Query: 549 PGRDHVHQLRLLMELIGTPNEADL 620 PG DH+ QL+L++ L+GTP ADL Sbjct: 223 PGTDHIDQLKLILRLVGTPG-ADL 245
>MK14_HUMAN (Q16539) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAX-interacting prote Length = 359 Score = 225 bits (574), Expect = 8e-59 Identities = 111/213 (52%), Positives = 151/213 (70%), Gaps = 2/213 (0%) Frame = +3 Query: 12 GSRWPSXKIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTA-FNDVYIAY 188 G R K++ F + I AKRT RE++LL+HM HEN++ + D+ PA+ FNDVY+ Sbjct: 46 GLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVT 105 Query: 189 ELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLK 368 LM DL+ I++ Q L+++H Q+ +YQILRGLKYIHSA+++HRDLKPSNL +N +C+LK Sbjct: 106 HLMGADLNNIVKC-QKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELK 164 Query: 369 ICDFGLARTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLF 548 I DFGLAR T D MT YV TRWYRAPE++LN Y +D+WSVGCI EL+ + LF Sbjct: 165 ILDFGLARHTD--DEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLF 222 Query: 549 PGRDHVHQLRLLMELIGTPNEADLDFV-NENAR 644 PG DH+ QL+L++ L+GTP L + +E+AR Sbjct: 223 PGTDHIDQLKLILRLVGTPGAELLKKISSESAR 255
>MK14_XENLA (P47812) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated Mitogen-activated protein kinase 2) (MAP kinase 2) (MPK2) Length = 361 Score = 225 bits (574), Expect = 8e-59 Identities = 107/204 (52%), Positives = 145/204 (71%), Gaps = 1/204 (0%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQR-TAFNDVYIAYELMDTDL 209 K++ F + I AKRT RE++LL+HM HEN++ + D+ PA+ FNDVY+ LM DL Sbjct: 55 KLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFSPAKSFEEFNDVYLVTHLMGADL 114 Query: 210 HQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLA 389 + I++ Q L+++H Q+ +YQILRGLKYIHSA ++HRDLKPSNL +N +C+LKI DFGLA Sbjct: 115 NNIVKC-QKLTDDHVQFLIYQILRGLKYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLA 173 Query: 390 RTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVH 569 R T E MT YV TRWYRAPE++LN Y +D+WSVGCI EL+ + LFPG DH+ Sbjct: 174 RHTDEE--MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHID 231 Query: 570 QLRLLMELIGTPNEADLDFVNENA 641 QL+L++ L+GTP L ++ A Sbjct: 232 QLKLILRLVGTPEPELLQKISSEA 255
>MK14_PANTR (Q95NE7) Mitogen-activated protein kinase 14 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) Length = 359 Score = 223 bits (567), Expect = 5e-58 Identities = 107/199 (53%), Positives = 143/199 (71%), Gaps = 1/199 (0%) Frame = +3 Query: 12 GSRWPSXKIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTA-FNDVYIAY 188 G R K++ F + I AKRT RE++LL+HM HEN++ + D+ PA+ FNDVY+ Sbjct: 46 GLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVT 105 Query: 189 ELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLK 368 LM DL+ I++ Q L+++H Q+ +YQILRGLKYIHSA+++HRDLKPSNL +N +C+LK Sbjct: 106 HLMGADLNNIVKC-QKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELK 164 Query: 369 ICDFGLARTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLF 548 I DFGLAR T D MT YV TRWYRAPE++LN Y +D+WSVGCI EL+ + LF Sbjct: 165 ILDFGLARHTD--DEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLF 222 Query: 549 PGRDHVHQLRLLMELIGTP 605 PG DH++QL+ +M L GTP Sbjct: 223 PGTDHINQLQQIMRLTGTP 241
>MK14B_CYPCA (Q9I958) Mitogen-activated protein kinase 14b (EC 2.7.11.24)| (Mitogen-activated protein kinase p38b) (MAP kinase p38b) (cp38b) Length = 361 Score = 223 bits (567), Expect = 5e-58 Identities = 108/199 (54%), Positives = 142/199 (71%), Gaps = 1/199 (0%) Frame = +3 Query: 12 GSRWPSXKIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTA-FNDVYIAY 188 G R K++ F + I AKRT RE++LL+HM HEN++ + D PA A FNDVY+ Sbjct: 48 GLRVAVKKLSRPFQSMIHAKRTYRELRLLKHMKHENVIGLLDAFSPATCLAGFNDVYLVT 107 Query: 189 ELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLK 368 LM DL+ I++ Q L+++H Q+ +YQILRGLKYIHSA+++HRDLKPSNL +N +C+LK Sbjct: 108 HLMGADLNNIVKC-QKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELK 166 Query: 369 ICDFGLARTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLF 548 I DFGLAR T D MT YV TRWYRAPE++LN Y +D+WSVGCI EL+ + LF Sbjct: 167 ILDFGLARLTD--DEMTGYVATRWYRAPEIMLNWMHYNMTVDIWSVGCIMAELLTGRTLF 224 Query: 549 PGRDHVHQLRLLMELIGTP 605 PG DH++QL+ +M L GTP Sbjct: 225 PGTDHINQLQQIMRLTGTP 243
>STY1_SCHPO (Q09892) Mitogen-activated protein kinase sty1 (EC 2.7.11.24) (MAP| kinase sty1) (MAP kinase spc1) Length = 349 Score = 221 bits (564), Expect = 1e-57 Identities = 106/191 (55%), Positives = 140/191 (73%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLH 212 KI F + AKRT RE+KLL+H+ HENI+++ DI + F D+Y EL+ TDLH Sbjct: 50 KIMKPFSTPVLAKRTYRELKLLKHLRHENIISLSDIFI----SPFEDIYFVTELLGTDLH 105 Query: 213 QIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLAR 392 +++ S + L + QYFLYQILRGLK++HSA V+HRDLKPSN+L+N NCDLKICDFGLAR Sbjct: 106 RLLTS-RPLETQFIQYFLYQILRGLKFVHSAGVIHRDLKPSNILINENCDLKICDFGLAR 164 Query: 393 TTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQ 572 + MT YV TR+YRAPE++L +Y +D+WS GCIF E+++ KPLFPGRDHV+Q Sbjct: 165 I--QDPQMTGYVSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGRDHVNQ 222 Query: 573 LRLLMELIGTP 605 ++ EL+GTP Sbjct: 223 FSIITELLGTP 233
>MK14A_CYPCA (Q90336) Mitogen-activated protein kinase 14a (EC 2.7.11.24)| (Mitogen-activated protein kinase p38a) (MAP kinase p38a) (cp38a) Length = 361 Score = 221 bits (563), Expect = 1e-57 Identities = 105/192 (54%), Positives = 140/192 (72%), Gaps = 1/192 (0%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTA-FNDVYIAYELMDTDL 209 K++ F + I AKRT RE++LL+HM HEN++ + D+ PA FNDVY+ LM DL Sbjct: 55 KLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPATSLEEFNDVYLVTHLMGADL 114 Query: 210 HQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLA 389 + I++ Q L+++H Q+ +YQILRGLKYIHSA+++HRDLKPSNL +N +C+LKI DFGLA Sbjct: 115 NNIVKC-QKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLA 173 Query: 390 RTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVH 569 R T D MT YV TRWYRAPE++LN Y +D+WSVGCI EL+ + LFPG DH++ Sbjct: 174 RHTD--DEMTGYVATRWYRAPEIMLNWMHYNMTVDIWSVGCIMAELLTGRTLFPGTDHIN 231 Query: 570 QLRLLMELIGTP 605 QL+ +M L GTP Sbjct: 232 QLQQIMRLTGTP 243
>MK14A_BRARE (Q9DGE2) Mitogen-activated protein kinase 14a (EC 2.7.11.24)| (Mitogen-activated protein kinase p38a) (MAP kinase p38a) (zp38a) Length = 361 Score = 221 bits (563), Expect = 1e-57 Identities = 105/192 (54%), Positives = 140/192 (72%), Gaps = 1/192 (0%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTA-FNDVYIAYELMDTDL 209 K++ F + I AKRT RE++LL+HM HEN++ + D+ PA FNDVY+ LM DL Sbjct: 55 KLSRPFQSIIHAKRTYRELRLLKHMRHENVIGLLDVFTPATSLKEFNDVYLVTHLMGADL 114 Query: 210 HQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLA 389 + I++ Q L+++H Q+ +YQILRGLKYIHSA+++HRDLKPSNL +N +C+LKI DFGLA Sbjct: 115 NNIVKC-QKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLA 173 Query: 390 RTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVH 569 R T D MT YV TRWYRAPE++LN Y +D+WSVGCI EL+ + LFPG DH++ Sbjct: 174 RHTD--DEMTGYVATRWYRAPEIMLNWMHYNVTVDIWSVGCIMAELLTGRTLFPGTDHIN 231 Query: 570 QLRLLMELIGTP 605 QL+ +M L GTP Sbjct: 232 QLQQIMRLTGTP 243
>MK14B_BRARE (Q9DGE1) Mitogen-activated protein kinase 14b (EC 2.7.11.24)| (Mitogen-activated protein kinase p38b) (MAP kinase p38b) (zp38b) Length = 348 Score = 220 bits (561), Expect = 2e-57 Identities = 106/199 (53%), Positives = 141/199 (70%), Gaps = 1/199 (0%) Frame = +3 Query: 12 GSRWPSXKIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRT-AFNDVYIAY 188 G R K++ F + I AKRT RE++LL+HM HEN++ + D+ PA FNDVY+ Sbjct: 48 GLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFSPATSLEGFNDVYLVT 107 Query: 189 ELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLK 368 LM DL+ I++ Q L+++H Q+ +YQILR LKYIHSA+++HRDLKPSNL +N +C+LK Sbjct: 108 HLMGADLNNIVKC-QKLTDDHVQFLIYQILRALKYIHSADIIHRDLKPSNLAVNEDCELK 166 Query: 369 ICDFGLARTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLF 548 I DFGLAR T D MT YV TRWYRAPE++LN Y +D+WSVGCI EL+ + LF Sbjct: 167 ILDFGLARLTD--DEMTGYVATRWYRAPEIMLNWMHYNMTVDIWSVGCIMAELLTGRTLF 224 Query: 549 PGRDHVHQLRLLMELIGTP 605 PG DH++QL+ +M L GTP Sbjct: 225 PGTDHINQLQQIMRLTGTP 243
>HOG1_ASHGO (Q750A9) Mitogen-activated protein kinase HOG1 (EC 2.7.11.24) (MAP| kinase HOG1) Length = 447 Score = 220 bits (560), Expect = 3e-57 Identities = 103/199 (51%), Positives = 143/199 (71%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLH 212 KI F + AKRT RE+KLL+H+ HEN++ + DI + D+Y EL TDLH Sbjct: 53 KIMKPFSTAVLAKRTYRELKLLKHLRHENLICLEDIF----LSPLEDIYFVTELQGTDLH 108 Query: 213 QIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLAR 392 +++++ + L ++ QYFLYQILRGLKY+HSA V+HRDLKPSN+L+N NCDLKICDFGLAR Sbjct: 109 RLLQT-RPLEKQFLQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLAR 167 Query: 393 TTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQ 572 + MT YV TR+YRAPE++L +Y +D+WS GCIF E+++ KPLFPG+DHVHQ Sbjct: 168 I--QDPQMTGYVSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQ 225 Query: 573 LRLLMELIGTPNEADLDFV 629 ++ +L+G+P + +D + Sbjct: 226 FSIITDLLGSPPKDVIDTI 244
>HOG1_ZYGRO (O93982) Mitogen-activated protein kinase HOG1 (EC 2.7.11.24) (MAP| kinase HOG1) Length = 380 Score = 219 bits (557), Expect = 7e-57 Identities = 102/191 (53%), Positives = 140/191 (73%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLH 212 KI F + AKRT RE+KLL+H+ HEN++ ++DI + D+Y EL TDLH Sbjct: 53 KIMKPFSTAVLAKRTYRELKLLKHLRHENLICLQDIF----LSPLEDIYFVTELQGTDLH 108 Query: 213 QIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLAR 392 +++++ + L ++ QYFLYQILRGLKY+HSA V+HRDLKPSN+L+N NCDLKICDFGLAR Sbjct: 109 RLLQT-RPLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLAR 167 Query: 393 TTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQ 572 + MT YV TR+YRAPE++L +Y +D+WS GCIF E+++ KPLFPG+DHVHQ Sbjct: 168 I--QDPQMTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFSEMIEGKPLFPGKDHVHQ 225 Query: 573 LRLLMELIGTP 605 ++ +L+G+P Sbjct: 226 FSIITDLLGSP 236
>HOG1_YEAST (P32485) Mitogen-activated protein kinase HOG1 (EC 2.7.11.24) (MAP| kinase HOG1) (Osmosensing protein HOG1) Length = 435 Score = 219 bits (557), Expect = 7e-57 Identities = 102/191 (53%), Positives = 140/191 (73%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLH 212 KI F + AKRT RE+KLL+H+ HEN++ ++DI + D+Y EL TDLH Sbjct: 53 KIMKPFSTAVLAKRTYRELKLLKHLRHENLICLQDIF----LSPLEDIYFVTELQGTDLH 108 Query: 213 QIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLAR 392 +++++ + L ++ QYFLYQILRGLKY+HSA V+HRDLKPSN+L+N NCDLKICDFGLAR Sbjct: 109 RLLQT-RPLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLAR 167 Query: 393 TTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQ 572 + MT YV TR+YRAPE++L +Y +D+WS GCIF E+++ KPLFPG+DHVHQ Sbjct: 168 I--QDPQMTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQ 225 Query: 573 LRLLMELIGTP 605 ++ +L+G+P Sbjct: 226 FSIITDLLGSP 236
>SLT2_YEAST (Q00772) Mitogen-activated protein kinase SLT2/MPK1 (EC 2.7.11.24)| (MAP kinase MPK1) Length = 484 Score = 218 bits (554), Expect = 2e-56 Identities = 110/203 (54%), Positives = 144/203 (70%), Gaps = 7/203 (3%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHM-DHENIVAIRDI-IPPAQRTAFNDVYIAYELMDTD 206 K+ N F + KR+LRE+KLLRH H+NI + D+ I + N +Y+ ELM+ D Sbjct: 55 KVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFYPDGSINGLYLYEELMECD 114 Query: 207 LHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGL 386 +HQII+S Q L++ H Q F YQIL GLKYIHSA+VLHRDLKP NLL+NA+C LKICDFGL Sbjct: 115 MHQIIKSGQPLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGL 174 Query: 387 ARTTSE-----TDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFP 551 AR SE + F+TEYV TRWYRAPE++L+ YT AIDVWS GCI E + KP+F Sbjct: 175 ARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFLGGKPIFK 234 Query: 552 GRDHVHQLRLLMELIGTPNEADL 620 G+D+V+QL +++++GTP + L Sbjct: 235 GKDYVNQLNQILQVLGTPPDETL 257
>HOG1_CANAL (Q92207) Mitogen-activated protein kinase HOG1 (EC 2.7.11.24) (MAP| kinase HOG1) Length = 377 Score = 217 bits (553), Expect = 2e-56 Identities = 107/210 (50%), Positives = 144/210 (68%), Gaps = 1/210 (0%) Frame = +3 Query: 3 RXRGSRWPSXKIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDI-IPPAQRTAFNDVY 179 R G K+ F + AKRT RE+KLL+H+ HEN++ + DI I P + D+Y Sbjct: 43 RLTGQNVAVKKVMKPFSTSVLAKRTYRELKLLKHLKHENLITLDDIFISPLE-----DIY 97 Query: 180 IAYELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANC 359 EL TDLH+++ S + L ++ QYF YQI+RGLKYIHSA V+HRDLKPSN+L+N NC Sbjct: 98 FVNELQGTDLHRLLNS-RPLEKQFIQYFTYQIMRGLKYIHSAGVIHRDLKPSNILINENC 156 Query: 360 DLKICDFGLARTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRK 539 DLKICDFGLAR + MT YV TR+YRAPE++L +Y +D+WSVGCI E+++ K Sbjct: 157 DLKICDFGLARL--QDPQMTGYVSTRYYRAPEIMLTWQKYDTEVDLWSVGCILAEMIEGK 214 Query: 540 PLFPGRDHVHQLRLLMELIGTPNEADLDFV 629 PLFPG+DHVHQ ++ EL+G+P +D + Sbjct: 215 PLFPGKDHVHQFSIITELLGSPPADVIDTI 244
>NLK_MOUSE (O54949) Serine/threonine kinase NLK (EC 2.7.11.24) (Nemo-like| kinase) Length = 515 Score = 217 bits (552), Expect = 3e-56 Identities = 104/201 (51%), Positives = 141/201 (70%), Gaps = 2/201 (0%) Frame = +3 Query: 12 GSRWPSXKIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYE 191 G R K+ N F N + KR RE+K+L H+N+++ DI+ P F ++Y+ E Sbjct: 149 GKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDNVLSALDILQPPHIDYFEEIYVVTE 208 Query: 192 LMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKI 371 LM +DLH+II S Q LS +H + FLYQILRGLKY+HSA +LHRD+KP NLL+N+NC LKI Sbjct: 209 LMQSDLHKIIVSPQPLSSDHVKVFLYQILRGLKYLHSAGILHRDIKPGNLLVNSNCVLKI 268 Query: 372 CDFGLART--TSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPL 545 CDFGLAR E+ MT+ VVT++YRAPE+L+ S Y+ AID+WSVGCIF EL+ R+ L Sbjct: 269 CDFGLARVEELDESRHMTQEVVTQYYRAPEILMGSRHYSNAIDIWSVGCIFAELLGRRIL 328 Query: 546 FPGRDHVHQLRLLMELIGTPN 608 F + + QL L+ +L+GTP+ Sbjct: 329 FQAQSPIQQLDLITDLLGTPS 349
>NLK_HUMAN (Q9UBE8) Serine/threonine kinase NLK (EC 2.7.11.24) (Nemo-like| kinase) (LAK1 protein) Length = 515 Score = 217 bits (552), Expect = 3e-56 Identities = 104/201 (51%), Positives = 141/201 (70%), Gaps = 2/201 (0%) Frame = +3 Query: 12 GSRWPSXKIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYE 191 G R K+ N F N + KR RE+K+L H+N+++ DI+ P F ++Y+ E Sbjct: 149 GKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDNVLSALDILQPPHIDYFEEIYVVTE 208 Query: 192 LMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKI 371 LM +DLH+II S Q LS +H + FLYQILRGLKY+HSA +LHRD+KP NLL+N+NC LKI Sbjct: 209 LMQSDLHKIIVSPQPLSSDHVKVFLYQILRGLKYLHSAGILHRDIKPGNLLVNSNCVLKI 268 Query: 372 CDFGLART--TSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPL 545 CDFGLAR E+ MT+ VVT++YRAPE+L+ S Y+ AID+WSVGCIF EL+ R+ L Sbjct: 269 CDFGLARVEELDESRHMTQEVVTQYYRAPEILMGSRHYSNAIDIWSVGCIFAELLGRRIL 328 Query: 546 FPGRDHVHQLRLLMELIGTPN 608 F + + QL L+ +L+GTP+ Sbjct: 329 FQAQSPIQQLDLITDLLGTPS 349
>HOG1_CANGA (Q6FIU2) Mitogen-activated protein kinase HOG1 (EC 2.7.11.24) (MAP| kinase HOG1) Length = 447 Score = 216 bits (549), Expect = 6e-56 Identities = 102/199 (51%), Positives = 142/199 (71%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLH 212 KI F + AKRT RE+KLL+H+ HEN++ ++DI + D+Y EL TDLH Sbjct: 53 KIMKPFATAVLAKRTYRELKLLKHLRHENLICLQDIF----LSPLEDIYFVTELQGTDLH 108 Query: 213 QIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLAR 392 +++++ + L ++ QYF YQILRGLKY+HSA V+HRDLKPSN+L+N NCDLKICDFGLAR Sbjct: 109 RLLQT-RPLEKQFVQYFHYQILRGLKYVHSAGVVHRDLKPSNILINENCDLKICDFGLAR 167 Query: 393 TTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQ 572 + MT YV TR+YRAPE++L +Y +D+WS GCIF E+++ KPLFPG+DHVHQ Sbjct: 168 I--QDPQMTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQ 225 Query: 573 LRLLMELIGTPNEADLDFV 629 ++ +L+G+P +D + Sbjct: 226 FSIITDLLGSPPSDVIDTI 244
>HOG1_DEBHA (Q9UV50) Mitogen-activated protein kinase HOG1 (EC 2.7.11.24) (MAP| kinase HOG1) Length = 387 Score = 214 bits (546), Expect = 1e-55 Identities = 103/191 (53%), Positives = 137/191 (71%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLH 212 KI F + AKRT RE+KLL+H+ HEN++ + DI + D+Y EL TDLH Sbjct: 53 KIMKPFLTSVLAKRTYRELKLLKHLRHENLITLDDIF----LSPLEDIYFVTELQGTDLH 108 Query: 213 QIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLAR 392 +++ S + L ++ QYF YQILRGLKY+HSA V+HRDLKPSN+L+N NCDLKICDFGLAR Sbjct: 109 RLLTS-RPLEKQFIQYFTYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLAR 167 Query: 393 TTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQ 572 + MT YV TR+YRAPE++L +Y +D+WSVGCI E+++ KPLFPG+DHVHQ Sbjct: 168 I--QDPQMTGYVSTRYYRAPEIMLTWQKYDTEVDLWSVGCILSEMIEGKPLFPGKDHVHQ 225 Query: 573 LRLLMELIGTP 605 ++ EL+G+P Sbjct: 226 FSIITELLGSP 236
>MK11_MOUSE (Q9WUI1) Mitogen-activated protein kinase 11 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38B) Length = 364 Score = 214 bits (545), Expect = 2e-55 Identities = 103/206 (50%), Positives = 146/206 (70%), Gaps = 2/206 (0%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTA-FNDVYIAYELMDTDL 209 K++ F + I A+RT RE++LL+H+ HEN++ + D+ PA F++VY+ LM DL Sbjct: 54 KLSRPFQSLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADL 113 Query: 210 HQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLA 389 + I++ QALS+EH Q+ +YQ+LRGLKYIHSA ++HRDLKPSN+ +N +C+L+I DFGLA Sbjct: 114 NNIVKC-QALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLA 172 Query: 390 RTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVH 569 E MT YV TRWYRAPE++LN Y +D+WSVGCI EL+ K LFPG D++ Sbjct: 173 PQADEE--MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGNDYID 230 Query: 570 QLRLLMELIGTPN-EADLDFVNENAR 644 QL+ +ME++GTP+ E +E+AR Sbjct: 231 QLKRIMEVVGTPSPEVLAKISSEHAR 256
>KKQ1_YEAST (P36005) Probable serine/threonine-protein kinase YKL161C (EC| 2.7.11.1) Length = 433 Score = 210 bits (534), Expect = 3e-54 Identities = 110/203 (54%), Positives = 140/203 (68%), Gaps = 7/203 (3%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHM-DHENIVAIRDI-IPPAQRTAFNDVYIAYELMDTD 206 KI NAF NK+ KRTLRE+KLLRH+ H NIV + D I A N VY+ ELM+ D Sbjct: 55 KIPNAFGNKLSCKRTLRELKLLRHLRGHPNIVWLFDTDIVFYPNGALNGVYLYEELMECD 114 Query: 207 LHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGL 386 L QIIRS Q L + H Q F+YQIL LKYIHSANVLH DLKP NLL+N++C LKIC+FGL Sbjct: 115 LSQIIRSEQRLEDAHFQSFIYQILCALKYIHSANVLHCDLKPKNLLVNSDCQLKICNFGL 174 Query: 387 ARTTSET-----DFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFP 551 + + SE F+ Y+ + WY+APE+LLN E T A+D+WS GCI EL+ RKP+F Sbjct: 175 SCSYSENHKVNDGFIKGYITSIWYKAPEILLNYQECTKAVDIWSTGCILAELLGRKPMFE 234 Query: 552 GRDHVHQLRLLMELIGTPNEADL 620 G+D+V L +++++GTP E L Sbjct: 235 GKDYVDHLNHILQILGTPPEETL 257
>PMK1_CAEEL (Q17446) Mitogen-activated protein kinase pmk-1 (EC 2.7.11.24) (p38| MAP kinase 1) (Stress-activated protein kinase pmk-1) Length = 377 Score = 208 bits (530), Expect = 1e-53 Identities = 109/213 (51%), Positives = 142/213 (66%), Gaps = 2/213 (0%) Frame = +3 Query: 12 GSRWPSXKIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTA-FNDVYIAY 188 G+R K F + I A+RT RE++LLR M HENI+ + D+ P + DVY Sbjct: 58 GTRVAIKKFNRPFQSIIHARRTYRELRLLRCMCHENIIDLLDVFTPNENVNDIEDVYFVS 117 Query: 189 ELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLK 368 LM DL I++ Q L+++H Q+ +YQILRGLKYIHSA+++HRDLKPSN+ +N +C+LK Sbjct: 118 MLMGADLSNILKI-QRLNDDHIQFLVYQILRGLKYIHSADIIHRDLKPSNIAVNEDCELK 176 Query: 369 ICDFGLARTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLF 548 I DFGLAR T MT YV TRWYRAPE++LN YT +DVWSVGCI EL+ K LF Sbjct: 177 ILDFGLARQTDSE--MTGYVATRWYRAPEIMLNWMHYTQTVDVWSVGCILAELITGKTLF 234 Query: 549 PGRDHVHQLRLLMELIGTPNEADLDFV-NENAR 644 PG DH+ QL +M + GTP+E L + +E AR Sbjct: 235 PGSDHIDQLTRIMSVTGTPDEEFLKKISSEEAR 267
>MK11_HUMAN (Q15759) Mitogen-activated protein kinase 11 (EC 2.7.11.24)| (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38b) (p38-2) (Stress-activated protein kinase 2) Length = 372 Score = 206 bits (525), Expect = 4e-53 Identities = 100/213 (46%), Positives = 143/213 (67%), Gaps = 9/213 (4%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTA-FNDVYIAYELMDTDL 209 K++ F + I A+RT RE++LL+H+ HEN++ + D+ PA F++VY+ LM DL Sbjct: 54 KLSRPFQSLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADL 113 Query: 210 HQIIRSNQALSE-------EHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLK 368 + I++ + EH Q+ +YQ+LRGLKYIHSA ++HRDLKPSN+ +N +C+L+ Sbjct: 114 NNIVKCQAGAHQGARLALDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELR 173 Query: 369 ICDFGLARTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLF 548 I DFGLAR E MT YV TRWYRAPE++LN Y +D+WSVGCI EL+ K LF Sbjct: 174 ILDFGLARQADEE--MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALF 231 Query: 549 PGRDHVHQLRLLMELIGTPN-EADLDFVNENAR 644 PG D++ QL+ +ME++GTP+ E +E+AR Sbjct: 232 PGSDYIDQLKRIMEVVGTPSPEVLAKISSEHAR 264
>MK15_HUMAN (Q8TD08) Mitogen-activated protein kinase 15 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 8) Length = 544 Score = 202 bits (514), Expect = 7e-52 Identities = 99/203 (48%), Positives = 138/203 (67%), Gaps = 7/203 (3%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHM-DHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDL 209 KI +AF +K DA+RT REI LL+ DH NI+++ D+I D+Y+ +E MDTDL Sbjct: 43 KIFDAFRDKTDAQRTFREITLLQEFGDHPNIISLLDVIRAEND---RDIYLVFEFMDTDL 99 Query: 210 HQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLA 389 + +IR L + H + YQ+LR +++HS +V+HRD KPSN+LL+ANC +K+CDFGLA Sbjct: 100 NAVIRKGGLLQDVHVRSIFYQLLRATRFLHSGHVVHRDQKPSNVLLDANCTVKLCDFGLA 159 Query: 390 RTTS------ETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFP 551 R+ E +TEYV TRWYRAPE+LL+S YT +D+WS+GCI E++ +PLFP Sbjct: 160 RSLGDLPEGPEDQAVTEYVATRWYRAPEVLLSSHRYTLGVDMWSLGCILGEMLRGRPLFP 219 Query: 552 GRDHVHQLRLLMELIGTPNEADL 620 G +HQL L++E I P+E DL Sbjct: 220 GTSTLHQLELILETIPPPSEEDL 242
>MK12_MOUSE (O08911) Mitogen-activated protein kinase 12 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 6) (ERK-6) (Stress-activated protein kinase 3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) Length = 367 Score = 199 bits (506), Expect = 6e-51 Identities = 95/199 (47%), Positives = 137/199 (68%), Gaps = 1/199 (0%) Frame = +3 Query: 12 GSRWPSXKIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTA-FNDVYIAY 188 G++ K+ F +++ AKR RE++LL+HM HEN++ + D+ P + F D Y+ Sbjct: 50 GNKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDESLDDFTDFYLVM 109 Query: 189 ELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLK 368 M TDL ++++ ++ LSE+ Q+ +YQ+L+GLKYIH+A V+HRDLKP NL +N +C+LK Sbjct: 110 PFMGTDLGKLMK-HETLSEDRIQFLVYQMLKGLKYIHAAGVIHRDLKPGNLAVNEDCELK 168 Query: 369 ICDFGLARTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLF 548 I DFGLAR MT YVVTRWYRAPE++LN YT +D+WSVGCI E++ K LF Sbjct: 169 ILDFGLARQADSE--MTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKILF 226 Query: 549 PGRDHVHQLRLLMELIGTP 605 G DH+ QL+ +M++ GTP Sbjct: 227 KGNDHLDQLKEIMKITGTP 245
>MK12_BRARE (O42376) Mitogen-activated protein kinase 12 (EC 2.7.11.24)| (Stress-activated protein kinase 3) Length = 363 Score = 199 bits (506), Expect = 6e-51 Identities = 100/216 (46%), Positives = 142/216 (65%), Gaps = 2/216 (0%) Frame = +3 Query: 3 RXRGSRWPSXKIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPP-AQRTAFNDVY 179 R G++ K+ F + + AKR RE++LL+HM H+N++ + D+ F+D Y Sbjct: 45 RRTGAKVAIKKLHRPFQSDLFAKRAYRELRLLKHMKHDNVIGLVDVFTADLSLDRFHDFY 104 Query: 180 IAYELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANC 359 + M TDL ++++ + LSEE QY +YQ+L+GLKYIH+A ++HRDLKP NL +N C Sbjct: 105 LVMPFMGTDLGKLMKMER-LSEERVQYLVYQMLKGLKYIHAAGIIHRDLKPGNLAINEEC 163 Query: 360 DLKICDFGLARTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRK 539 +LKI DFGLAR T MT YVVTRWYRAPE++L+ YT +D+WSVGCI E++ K Sbjct: 164 ELKILDFGLARQTDSE--MTGYVVTRWYRAPEVILSWMHYTQTVDIWSVGCIMAEMLLGK 221 Query: 540 PLFPGRDHVHQLRLLMELIGTPN-EADLDFVNENAR 644 PLF G DH+ QL +M++ GTP+ E +E+AR Sbjct: 222 PLFKGHDHLDQLMEIMKVTGTPSKEFTAKLQSEDAR 257
>MK12_RAT (Q63538) Mitogen-activated protein kinase 12 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 6) (ERK-6) (Stress-activated protein kinase 3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) Length = 367 Score = 199 bits (505), Expect = 8e-51 Identities = 95/199 (47%), Positives = 137/199 (68%), Gaps = 1/199 (0%) Frame = +3 Query: 12 GSRWPSXKIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTA-FNDVYIAY 188 G++ K+ F +++ AKR RE++LL+HM HEN++ + D+ P + F D Y+ Sbjct: 50 GNKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVM 109 Query: 189 ELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLK 368 M TDL ++++ ++ LSE+ Q+ +YQ+L+GLKYIH+A V+HRDLKP NL +N +C+LK Sbjct: 110 PFMGTDLGKLMK-HETLSEDRIQFLVYQMLKGLKYIHAAGVIHRDLKPGNLAVNEDCELK 168 Query: 369 ICDFGLARTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLF 548 I DFGLAR MT YVVTRWYRAPE++LN YT +D+WSVGCI E++ K LF Sbjct: 169 ILDFGLARQADSE--MTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKILF 226 Query: 549 PGRDHVHQLRLLMELIGTP 605 G DH+ QL+ +M++ GTP Sbjct: 227 KGNDHLDQLKEIMKVTGTP 245
>MK12_HUMAN (P53778) Mitogen-activated protein kinase 12 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 6) (ERK-6) (ERK5) (Stress-activated protein kinase 3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) Length = 367 Score = 196 bits (497), Expect = 6e-50 Identities = 92/199 (46%), Positives = 136/199 (68%), Gaps = 1/199 (0%) Frame = +3 Query: 12 GSRWPSXKIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTA-FNDVYIAY 188 G++ K+ F +++ AKR RE++LL+HM HEN++ + D+ P + F D Y+ Sbjct: 50 GAKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVM 109 Query: 189 ELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLK 368 M TDL ++++ ++ L E+ Q+ +YQ+L+GL+YIH+A ++HRDLKP NL +N +C+LK Sbjct: 110 PFMGTDLGKLMK-HEKLGEDRIQFLVYQMLKGLRYIHAAGIIHRDLKPGNLAVNEDCELK 168 Query: 369 ICDFGLARTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLF 548 I DFGLAR MT YVVTRWYRAPE++LN YT +D+WSVGCI E++ K LF Sbjct: 169 ILDFGLARQADSE--MTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKTLF 226 Query: 549 PGRDHVHQLRLLMELIGTP 605 G DH+ QL+ +M++ GTP Sbjct: 227 KGSDHLDQLKEIMKVTGTP 245
>MK13_PANTR (Q9N272) Mitogen-activated protein kinase 13 (EC 2.7.11.24)| (Stress-activated protein kinase 4) Length = 365 Score = 195 bits (496), Expect = 8e-50 Identities = 97/211 (45%), Positives = 136/211 (64%), Gaps = 1/211 (0%) Frame = +3 Query: 12 GSRWPSXKIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTA-FNDVYIAY 188 G + K++ F ++I AKR RE+ LL+HM HEN++ + D+ PA F+D Y+ Sbjct: 48 GEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFHDFYLVM 107 Query: 189 ELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLK 368 M TDL +I+ SEE QY +YQ+L+GLKYIHSA V+HRDLKP NL +N +C+LK Sbjct: 108 XFMQTDLQKIMXME--FSEEKIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNEDCELK 165 Query: 369 ICDFGLARTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLF 548 I DFGLAR MT YVVTRWYRAPE++L+ Y +D+WSVGCI E++ K LF Sbjct: 166 ILDFGLARHADAE--MTGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLF 223 Query: 549 PGRDHVHQLRLLMELIGTPNEADLDFVNENA 641 G+D++ QL ++++ G P + +N+ A Sbjct: 224 KGKDYLDQLTQILKVTGVPGTEFVQKLNDXA 254
>MK13_HUMAN (O15264) Mitogen-activated protein kinase 13 (EC 2.7.11.24)| (Stress-activated protein kinase 4) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) Length = 365 Score = 195 bits (495), Expect = 1e-49 Identities = 97/211 (45%), Positives = 135/211 (63%), Gaps = 1/211 (0%) Frame = +3 Query: 12 GSRWPSXKIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTA-FNDVYIAY 188 G + K++ F ++I AKR RE+ LL+HM HEN++ + D+ PA F D Y+ Sbjct: 48 GEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFYDFYLVM 107 Query: 189 ELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLK 368 M TDL +I+ SEE QY +YQ+L+GLKYIHSA V+HRDLKP NL +N +C+LK Sbjct: 108 PFMQTDLQKIM--GMEFSEEKIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNEDCELK 165 Query: 369 ICDFGLARTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLF 548 I DFGLAR MT YVVTRWYRAPE++L+ Y +D+WSVGCI E++ K LF Sbjct: 166 ILDFGLARHADAE--MTGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLF 223 Query: 549 PGRDHVHQLRLLMELIGTPNEADLDFVNENA 641 G+D++ QL ++++ G P + +N+ A Sbjct: 224 KGKDYLDQLTQILKVTGVPGTEFVQKLNDKA 254
>MK13_MOUSE (Q9Z1B7) Mitogen-activated protein kinase 13 (EC 2.7.11.24)| (Stress-activated protein kinase 4) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) Length = 366 Score = 194 bits (494), Expect = 1e-49 Identities = 94/199 (47%), Positives = 133/199 (66%), Gaps = 1/199 (0%) Frame = +3 Query: 12 GSRWPSXKIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRT-AFNDVYIAY 188 G + K++ F ++I AKR RE+ LL+HM HEN++ + D+ PA +F+D Y+ Sbjct: 48 GEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMHHENVIGLLDVFTPASSLRSFHDFYLVM 107 Query: 189 ELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLK 368 M TDL +I+ SE+ QY +YQ+L+GLKYIHSA ++HRDLKP NL +N +C+LK Sbjct: 108 PFMQTDLQKIM--GMEFSEDKVQYLVYQMLKGLKYIHSAGIVHRDLKPGNLAVNEDCELK 165 Query: 369 ICDFGLARTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLF 548 I DFGLAR T MT YVVTRWYRAPE++L+ Y +D+WSVGCI E++ K LF Sbjct: 166 ILDFGLARHTDTE--MTGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLF 223 Query: 549 PGRDHVHQLRLLMELIGTP 605 G+D++ QL ++++ G P Sbjct: 224 KGKDYLDQLTQILKVTGVP 242
>PMK2_CAEEL (Q8MXI4) Mitogen-activated protein kinase pmk-2 (EC 2.7.11.24) (p38| MAP kinase 2) (Stress-activated protein kinase pmk-2) Length = 419 Score = 194 bits (493), Expect = 2e-49 Identities = 101/218 (46%), Positives = 134/218 (61%), Gaps = 18/218 (8%) Frame = +3 Query: 12 GSRWPSXKIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPP-AQRTAFNDVYIAY 188 G R K F + I AKRT RE+KLLR + H+N++ + D+ P ++ N+VY Sbjct: 72 GDRVAIKKFFRPFQSTIHAKRTYRELKLLRTLQHDNVLEMIDVFTPDPDASSLNNVYFVS 131 Query: 189 ELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLK 368 LM +DL I++ Q L++E Q +YQ+LRGLKYIHSA ++HRDLKPSN+ +N C++K Sbjct: 132 VLMGSDLQNIMKI-QRLTDEQIQLLIYQVLRGLKYIHSAGIIHRDLKPSNIAVNERCEVK 190 Query: 369 -----------------ICDFGLARTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDV 497 I DFGLAR MT YV TRWYRAPE++LN YT +DV Sbjct: 191 VFLSFSQLSFLILSFFKILDFGLARAQDAE--MTGYVATRWYRAPEIMLNWMHYTQTVDV 248 Query: 498 WSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPNE 611 WSVGCI EL+ +PLFPG DH+ QL +M ++GTP E Sbjct: 249 WSVGCILAELVSGRPLFPGDDHIDQLTKIMSVVGTPKE 286
>MK13_RAT (Q9WTY9) Mitogen-activated protein kinase 13 (EC 2.7.11.24)| (Stress-activated protein kinase 4) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) Length = 366 Score = 194 bits (493), Expect = 2e-49 Identities = 95/199 (47%), Positives = 131/199 (65%), Gaps = 1/199 (0%) Frame = +3 Query: 12 GSRWPSXKIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTA-FNDVYIAY 188 G + K++ F ++I AKR RE+ LL+HM HEN++ + D+ PA F D Y+ Sbjct: 48 GEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMHHENVIGLLDVYTPATSVRNFQDFYLVM 107 Query: 189 ELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLK 368 M TDL +I+ SEE QY +YQ+L+GLKYIHSA ++HRDLKP NL +N +C+LK Sbjct: 108 PFMQTDLQKIM--GMEFSEEKVQYLVYQMLKGLKYIHSAGIVHRDLKPGNLAVNEDCELK 165 Query: 369 ICDFGLARTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLF 548 I DFGLAR T MT YVVTRWYRAPE++L+ Y +D+WSVGCI E++ K LF Sbjct: 166 ILDFGLARHTDAE--MTGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLF 223 Query: 549 PGRDHVHQLRLLMELIGTP 605 G+D++ QL ++++ G P Sbjct: 224 KGKDYLDQLTQILKVTGVP 242
>MK15_RAT (Q9Z2A6) Mitogen-activated protein kinase 15 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 7) Length = 547 Score = 191 bits (485), Expect = 2e-48 Identities = 96/203 (47%), Positives = 135/203 (66%), Gaps = 7/203 (3%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMD-HENIVAIRDIIPPAQRTAFNDVYIAYELMDTDL 209 KI +AF ++ DA+RT REI LLR H NI+ + D+IP D+Y+ +E MDTDL Sbjct: 44 KIFDAFRDQTDAQRTFREIMLLREFGGHPNIIRLLDVIPAKND---RDIYLVFESMDTDL 100 Query: 210 HQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLA 389 + +I+ + L + H + YQ+LR K+IHS V+HRD KP+N+LL+A C +K+CDFGLA Sbjct: 101 NAVIQKGRLLEDIHKRCIFYQLLRATKFIHSGRVIHRDQKPANVLLDAACRVKLCDFGLA 160 Query: 390 RTTSE------TDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFP 551 R+ S+ +TEYV TRWYRAPE+LL+S YT +D+WS+GCI E++ +PLFP Sbjct: 161 RSLSDFPEGPGGQALTEYVATRWYRAPEVLLSSRWYTPGVDMWSLGCILGEMLRGQPLFP 220 Query: 552 GRDHVHQLRLLMELIGTPNEADL 620 G HQL L++E I P+ +L Sbjct: 221 GTSTFHQLELILETIPLPSMEEL 243
>JNK1_CAEEL (Q8WQG9) Stress-activated protein kinase jnk-1 (EC 2.7.11.24)| Length = 463 Score = 190 bits (483), Expect = 3e-48 Identities = 95/205 (46%), Positives = 138/205 (67%), Gaps = 1/205 (0%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRT-AFNDVYIAYELMDTDL 209 K++ F N AKR RE+KL+ ++H+NI+ I + P ++ FND+YI ELMD +L Sbjct: 149 KLSRPFQNVTHAKRAYRELKLMSLVNHKNIIGILNCFTPQKKLDEFNDLYIVMELMDANL 208 Query: 210 HQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLA 389 Q+I+ + L E Y LYQ+L G++++HSA ++HRDLKPSN+++ ++C LKI DFGLA Sbjct: 209 CQVIQMD--LDHERLSYLLYQMLCGIRHLHSAGIIHRDLKPSNIVVRSDCTLKILDFGLA 266 Query: 390 RTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVH 569 RT E MT YVVTR+YRAPE++L Y +DVWS+GCIF EL+ + LFPG DH+ Sbjct: 267 RTAIEAFMMTPYVVTRYYRAPEVILGMG-YKENVDVWSIGCIFGELIRGRVLFPGGDHID 325 Query: 570 QLRLLMELIGTPNEADLDFVNENAR 644 Q ++E +GTP+ + L+ + R Sbjct: 326 QWTRIIEQLGTPDRSFLERLQPTVR 350
>MK08A_CYPCA (Q90327) Mitogen-activated protein kinase 8A (EC 2.7.11.24)| (Stress-activated protein kinase JNKa) (c-Jun N-terminal kinase A) Length = 427 Score = 188 bits (478), Expect = 1e-47 Identities = 93/206 (45%), Positives = 142/206 (68%), Gaps = 2/206 (0%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTA--FNDVYIAYELMDTD 206 K++ F N+ AKR RE+ L+++++H+NI+ + ++ +Q+T F DVY+ ELMD + Sbjct: 56 KLSRPFQNQTHAKRAYRELVLMKYVNHKNIICLLNVFT-SQKTLDEFQDVYLVMELMDAN 114 Query: 207 LHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGL 386 L Q+I+ L E Y LYQ+L G+K++HSA ++HRDLKPSN+++ ++C LKI DFGL Sbjct: 115 LCQVIQME--LDHERLSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGL 172 Query: 387 ARTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHV 566 ART + MT YVVTR+YRAPE++L Y A +D+WSVGCI E++ K LFPGRD++ Sbjct: 173 ARTAATGLLMTPYVVTRYYRAPEVILGMG-YQANVDIWSVGCILAEMVRHKILFPGRDYI 231 Query: 567 HQLRLLMELIGTPNEADLDFVNENAR 644 Q ++E +GTP + + +N++ R Sbjct: 232 DQWNKVIEQLGTPTQEFMMKLNQSVR 257
>MK15_MOUSE (Q80Y86) Mitogen-activated protein kinase 15 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 7) Length = 549 Score = 188 bits (477), Expect = 1e-47 Identities = 93/203 (45%), Positives = 135/203 (66%), Gaps = 7/203 (3%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMD-HENIVAIRDIIPPAQRTAFNDVYIAYELMDTDL 209 KI +AF ++IDA+RT REI LL+ H NI+ + D+IP D+Y+ +E MDTDL Sbjct: 44 KIFDAFRDQIDAQRTFREIMLLKEFGGHPNIIRLLDVIPAKND---RDIYLVFESMDTDL 100 Query: 210 HQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLA 389 + +I+ + L + H + YQ+LR K+IHS V+HRD KP+N+LL++ C +K+CDFGLA Sbjct: 101 NAVIQKGRLLKDIHKRCIFYQLLRATKFIHSGRVIHRDQKPANVLLDSACRVKLCDFGLA 160 Query: 390 RTTSET------DFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFP 551 R+ + +TEYV TRWYRAPE+LL+S YT +D+WS+GCI E++ +PLFP Sbjct: 161 RSLGDLPEGPGGQALTEYVATRWYRAPEVLLSSRWYTPGVDMWSLGCILGEMLRGQPLFP 220 Query: 552 GRDHVHQLRLLMELIGTPNEADL 620 G HQL L+++ I P+ +L Sbjct: 221 GTSTFHQLELILKTIPLPSMEEL 243
>SMK1_YEAST (P41808) Sporulation-specific mitogen-activated protein kinase SMK1| (EC 2.7.11.24) (MAP kinase SMK1) Length = 388 Score = 187 bits (475), Expect = 2e-47 Identities = 99/213 (46%), Positives = 139/213 (65%), Gaps = 10/213 (4%) Frame = +3 Query: 3 RXRGSRWPSXKIANAFDNKIDAKRTLREIKLLRHMD-HENIVAIRDIIPPAQRTAFNDVY 179 R +R KI+N F+ +I KR +RE+K + H+NIV + D+ + ++ +Y Sbjct: 60 RSPAARIAVKKISNIFNKEILLKRAIRELKFMNFFKGHKNIVNLIDL-EIVTSSPYDGLY 118 Query: 180 IAYELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANC 359 EL+D DL ++I S+ LSE H +YFLYQIL GLKYIHSA+V+HRDLKP N+L N Sbjct: 119 CYQELIDYDLAKVIHSSVQLSEFHIKYFLYQILCGLKYIHSADVIHRDLKPGNILCTLNG 178 Query: 360 DLKICDFGLARTTSETDF---------MTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGC 512 LKICDFGLAR F +T YV TRWYRAPELLL++ Y+ ++D+W+VGC Sbjct: 179 CLKICDFGLARGIHAGFFKCHSTVQPHITNYVATRWYRAPELLLSNQPYSKSVDIWAVGC 238 Query: 513 IFMELMDRKPLFPGRDHVHQLRLLMELIGTPNE 611 I E RKP+F GRD +HQ+ +++++GTP++ Sbjct: 239 ILAEFYARKPVFMGRDSMHQIFEIIKVLGTPDK 271
>MK14C_DROME (P83100) Putative mitogen-activated protein kinase 14C (EC| 2.7.11.24) (MAP kinase p38c) Length = 356 Score = 187 bits (475), Expect = 2e-47 Identities = 96/205 (46%), Positives = 139/205 (67%), Gaps = 4/205 (1%) Frame = +3 Query: 3 RXRGSR--WPSXKIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDII-PPAQRTA-FN 170 R RG+ + ++ F+ + DAK T REI+LL+HM+H N++++ ++ PPA F Sbjct: 38 RLRGTENYFAMKRLMRPFEREEDAKGTYREIRLLKHMNHRNVISLLNVFHPPAHNMMEFQ 97 Query: 171 DVYIAYELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLN 350 VY+ LMD DLH+ RS + +S++ + LYQILRGLKYIHSA V+HRDLKP N+ +N Sbjct: 98 QVYLVTHLMDADLHRYSRSKR-MSDQEIRIILYQILRGLKYIHSAGVVHRDLKPCNIAVN 156 Query: 351 ANCDLKICDFGLARTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELM 530 N +++I DFGL+R + D MT++V T WY APE++ +YT AIDVWSVGCI EL+ Sbjct: 157 GNSEVRILDFGLSRMCA--DKMTDHVGTMWYLAPEIIFLRGQYTKAIDVWSVGCILAELI 214 Query: 531 DRKPLFPGRDHVHQLRLLMELIGTP 605 + LF G ++V Q+R L+ ++GTP Sbjct: 215 TDRVLFRGENYVSQIRCLINIMGTP 239
>JNK1_ANCCA (Q9U6D2) Stress-activated protein kinase JNK-1 (EC 2.7.11.24)| Length = 376 Score = 187 bits (474), Expect = 3e-47 Identities = 94/192 (48%), Positives = 130/192 (67%), Gaps = 1/192 (0%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTA-FNDVYIAYELMDTDL 209 K++ F N AKR RE L+ ++H+NI+ + + P + FND+YI ELMD +L Sbjct: 56 KLSRPFQNVTHAKRAYREFILMNLVNHKNIIGLLNAFSPQREVEEFNDLYIVMELMDANL 115 Query: 210 HQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLA 389 Q+I+ + L E Y LYQ+L G+K++HSA ++HRDLKPSN+++ ++C LKI DFGLA Sbjct: 116 CQVIQMD--LDHERLSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLA 173 Query: 390 RTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVH 569 RT E MT YVVTR+YRAPE++L Y +DVWSVGCIF EL+ + LFPG DH+ Sbjct: 174 RTAVEAFMMTPYVVTRYYRAPEVILGMG-YGENVDVWSVGCIFGELIRGRVLFPGADHID 232 Query: 570 QLRLLMELIGTP 605 Q ++EL+GTP Sbjct: 233 QWTRIIELLGTP 244
>MK08B_CYPCA (O42099) Mitogen-activated protein kinase 8B (EC 2.7.11.24)| (Stress-activated protein kinase JNKb) (c-Jun N-terminal kinase B) Length = 427 Score = 186 bits (472), Expect = 5e-47 Identities = 94/206 (45%), Positives = 139/206 (67%), Gaps = 2/206 (0%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTA--FNDVYIAYELMDTD 206 K++ F N+ AKR RE+ L++ ++H+NI+ + ++ P Q+T F DVY+ ELMD + Sbjct: 56 KLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTP-QKTLEEFQDVYLVMELMDAN 114 Query: 207 LHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGL 386 L Q+I+ L E Y LYQ+L G K++HSA ++HRDLKPSN+++ ++C LKI DFGL Sbjct: 115 LCQVIQME--LDHERLSYLLYQMLCGTKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGL 172 Query: 387 ARTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHV 566 ART + MT YVVTR+YRAPE++L Y A +DVWSVGCI E++ LFPG DH+ Sbjct: 173 ARTAATGLLMTPYVVTRYYRAPEVILGMG-YQANVDVWSVGCIMAEMVRGSVLFPGSDHI 231 Query: 567 HQLRLLMELIGTPNEADLDFVNENAR 644 Q ++E +GTP++ + +N++ R Sbjct: 232 DQWNKVIEQLGTPSQEFMMKLNQSVR 257
>MK08_BRARE (Q9DGD9) Mitogen-activated protein kinase 8 (EC 2.7.11.24)| (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1) Length = 384 Score = 186 bits (471), Expect = 7e-47 Identities = 92/206 (44%), Positives = 140/206 (67%), Gaps = 2/206 (0%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTA--FNDVYIAYELMDTD 206 K++ F N+ AKR RE+ L++ ++H+NI+ + ++ P Q+T F DVY+ ELMD + Sbjct: 56 KLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTP-QKTLEEFQDVYLVMELMDAN 114 Query: 207 LHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGL 386 L Q+I+ L E Y LYQ+L G+K++H+A ++HRDLKPSN+++ ++C LKI DFGL Sbjct: 115 LCQVIQME--LDHERLSYLLYQMLCGIKHLHAAGIIHRDLKPSNIVVKSDCTLKILDFGL 172 Query: 387 ARTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHV 566 ART + MT YVVTR+YRAPE++L Y A +DVWS+GCI E++ LFPG DH+ Sbjct: 173 ARTAATGLLMTPYVVTRYYRAPEVILGMG-YQANVDVWSIGCIMAEMVRGSVLFPGTDHI 231 Query: 567 HQLRLLMELIGTPNEADLDFVNENAR 644 Q ++E +GTP++ + +N++ R Sbjct: 232 DQWNKVIEQLGTPSQEFMMKLNQSVR 257
>JNK_DROME (P92208) Stress-activated protein kinase JNK (EC 2.7.11.24) (dJNK)| (Protein basket) Length = 372 Score = 185 bits (470), Expect = 9e-47 Identities = 92/205 (44%), Positives = 134/205 (65%), Gaps = 1/205 (0%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTA-FNDVYIAYELMDTDL 209 K++ F N AKR RE KL++ ++H+NI+ + + P + F DVY+ ELMD +L Sbjct: 54 KLSRPFQNVTHAKRAYREFKLMKLVNHKNIIGLLNAFTPQRNLEEFQDVYLVMELMDANL 113 Query: 210 HQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLA 389 Q+I+ + L + Y LYQ+L G+K++HSA ++HRDLKPSN+++ A+C LKI DFGLA Sbjct: 114 CQVIQMD--LDHDRMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKADCTLKILDFGLA 171 Query: 390 RTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVH 569 RT T MT YVVTR+YRAPE++L YT +D+WSVGCI E++ LFPG DH+ Sbjct: 172 RTAGTTFMMTPYVVTRYYRAPEVILGMG-YTENVDIWSVGCIMGEMIRGGVLFPGTDHID 230 Query: 570 QLRLLMELIGTPNEADLDFVNENAR 644 Q ++E +GTP+ + + + R Sbjct: 231 QWNKIIEQLGTPSPSFMQRLQPTVR 255
>MK09_MOUSE (Q9WTU6) Mitogen-activated protein kinase 9 (EC 2.7.11.24)| (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2) Length = 423 Score = 185 bits (469), Expect = 1e-46 Identities = 92/194 (47%), Positives = 134/194 (69%), Gaps = 2/194 (1%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTA--FNDVYIAYELMDTD 206 K++ F N+ AKR RE+ LL+ ++H+NI+++ ++ P Q+T F DVY+ ELMD + Sbjct: 56 KLSRPFQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTP-QKTLEEFQDVYLVMELMDAN 114 Query: 207 LHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGL 386 L Q+I + L E Y LYQ+L G+K++HSA ++HRDLKPSN+++ ++C LKI DFGL Sbjct: 115 LCQVI--HMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGL 172 Query: 387 ARTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHV 566 ART MT YVVTR+YRAPE++L Y +D+WSVGCI E++ K LFPGRD++ Sbjct: 173 ARTACTNFMMTPYVVTRYYRAPEVILGMG-YKENVDIWSVGCIMAEMVLHKVLFPGRDYI 231 Query: 567 HQLRLLMELIGTPN 608 Q ++E +GTP+ Sbjct: 232 DQWNKVIEQLGTPS 245
>MK10_HUMAN (P53779) Mitogen-activated protein kinase 10 (EC 2.7.11.24)| (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3) (MAP kinase p49 3F12) Length = 464 Score = 184 bits (467), Expect = 2e-46 Identities = 91/193 (47%), Positives = 134/193 (69%), Gaps = 2/193 (1%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTA--FNDVYIAYELMDTD 206 K++ F N+ AKR RE+ L++ ++H+NI+++ ++ P Q+T F DVY+ ELMD + Sbjct: 94 KLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTP-QKTLEEFQDVYLVMELMDAN 152 Query: 207 LHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGL 386 L Q+I+ L E Y LYQ+L G+K++HSA ++HRDLKPSN+++ ++C LKI DFGL Sbjct: 153 LCQVIQME--LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGL 210 Query: 387 ARTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHV 566 ART + MT YVVTR+YRAPE++L Y +D+WSVGCI E++ K LFPGRD++ Sbjct: 211 ARTAGTSFMMTPYVVTRYYRAPEVILGMG-YKENVDIWSVGCIMGEMVRHKILFPGRDYI 269 Query: 567 HQLRLLMELIGTP 605 Q ++E +GTP Sbjct: 270 DQWNKVIEQLGTP 282
>MK08_MOUSE (Q91Y86) Mitogen-activated protein kinase 8 (EC 2.7.11.24)| (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1) Length = 384 Score = 183 bits (464), Expect = 4e-46 Identities = 90/192 (46%), Positives = 131/192 (68%), Gaps = 1/192 (0%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTA-FNDVYIAYELMDTDL 209 K++ F N+ AKR RE+ L++ ++H+NI+ + ++ P + F DVYI ELMD +L Sbjct: 56 KLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANL 115 Query: 210 HQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLA 389 Q+I+ L E Y LYQ+L G+K++HSA ++HRDLKPSN+++ ++C LKI DFGLA Sbjct: 116 CQVIQME--LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLA 173 Query: 390 RTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVH 569 RT + MT YVVTR+YRAPE++L Y +D+WSVGCI E++ K LFPGRD++ Sbjct: 174 RTAGTSFMMTPYVVTRYYRAPEVILGMG-YKENVDLWSVGCIMGEMVCHKILFPGRDYID 232 Query: 570 QLRLLMELIGTP 605 Q ++E +GTP Sbjct: 233 QWNKVIEQLGTP 244
>MK08_HUMAN (P45983) Mitogen-activated protein kinase 8 (EC 2.7.11.24)| (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1) (JNK-46) Length = 427 Score = 183 bits (464), Expect = 4e-46 Identities = 90/192 (46%), Positives = 131/192 (68%), Gaps = 1/192 (0%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTA-FNDVYIAYELMDTDL 209 K++ F N+ AKR RE+ L++ ++H+NI+ + ++ P + F DVYI ELMD +L Sbjct: 56 KLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANL 115 Query: 210 HQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLA 389 Q+I+ L E Y LYQ+L G+K++HSA ++HRDLKPSN+++ ++C LKI DFGLA Sbjct: 116 CQVIQME--LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLA 173 Query: 390 RTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVH 569 RT + MT YVVTR+YRAPE++L Y +D+WSVGCI E++ K LFPGRD++ Sbjct: 174 RTAGTSFMMTPYVVTRYYRAPEVILGMG-YKENVDLWSVGCIMGEMVCHKILFPGRDYID 232 Query: 570 QLRLLMELIGTP 605 Q ++E +GTP Sbjct: 233 QWNKVIEQLGTP 244
>MK10_RAT (P49187) Mitogen-activated protein kinase 10 (EC 2.7.11.24)| (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3) (SAPK-beta) (p54-beta) Length = 464 Score = 182 bits (463), Expect = 6e-46 Identities = 90/193 (46%), Positives = 133/193 (68%), Gaps = 2/193 (1%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTA--FNDVYIAYELMDTD 206 K++ F N+ AKR RE+ L++ ++H+NI+++ ++ P Q+T F DVY+ ELMD + Sbjct: 94 KLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTP-QKTLEEFQDVYLVMELMDAN 152 Query: 207 LHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGL 386 L Q+I+ L E Y LYQ+L +K++HSA ++HRDLKPSN+++ ++C LKI DFGL Sbjct: 153 LCQVIQME--LDHERMSYLLYQMLSAIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGL 210 Query: 387 ARTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHV 566 ART + MT YVVTR+YRAPE++L Y +D+WSVGCI E++ K LFPGRD++ Sbjct: 211 ARTAGTSFMMTPYVVTRYYRAPEVILGMG-YKENVDIWSVGCIMGEMVRHKILFPGRDYI 269 Query: 567 HQLRLLMELIGTP 605 Q ++E +GTP Sbjct: 270 DQWNKVIEQLGTP 282
>JNK_SUBDO (Q966Y3) Stress-activated protein kinase JNK (EC 2.7.11.24)| Length = 361 Score = 182 bits (462), Expect = 7e-46 Identities = 87/192 (45%), Positives = 132/192 (68%), Gaps = 1/192 (0%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTA-FNDVYIAYELMDTDL 209 K+ F N+ AKR RE++L++ +DH+NI+ ++++ PA+ F DVYI ELMD +L Sbjct: 52 KLVKPFQNETYAKRAFRELRLMKMVDHKNIIGLKNLFTPAKSLDDFQDVYIVMELMDANL 111 Query: 210 HQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLA 389 ++I L + Y LYQ+L G+K++HSA ++HRDLKPSN+++ +C LKI DFGLA Sbjct: 112 CRVIGIE--LDHDRMSYLLYQLLCGIKHLHSAGIIHRDLKPSNIVVKEDCSLKILDFGLA 169 Query: 390 RTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVH 569 RT +T MT YVVTR+YRAPE+++ +Y +D+WSVGCIF E++ L PG+D++ Sbjct: 170 RTADQTFNMTPYVVTRYYRAPEVIV-GMKYKENVDIWSVGCIFAEMIRGDILLPGKDYID 228 Query: 570 QLRLLMELIGTP 605 Q + +++GTP Sbjct: 229 QWNKVTQVLGTP 240
>MK08_RAT (P49185) Mitogen-activated protein kinase 8 (EC 2.7.11.24)| (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1) (SAPK gamma) (p54 gamma) Length = 411 Score = 182 bits (462), Expect = 7e-46 Identities = 90/192 (46%), Positives = 131/192 (68%), Gaps = 1/192 (0%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTA-FNDVYIAYELMDTDL 209 K++ F N+ AKR RE+ L++ ++H+NI+ + ++ P + F DVYI ELMD +L Sbjct: 56 KLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANL 115 Query: 210 HQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLA 389 Q+I+ L E Y LYQ+L G+K++HSA ++HRDLKPSN+++ ++C LKI DFGLA Sbjct: 116 CQVIQME--LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLA 173 Query: 390 RTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVH 569 RT + MT YVVTR+YRAPE++L Y +D+WSVGCI E++ K LFPGRD++ Sbjct: 174 RTAGTSFMMTPYVVTRYYRAPEVILGMG-YKENVDLWSVGCIMGEMVCLKILFPGRDYID 232 Query: 570 QLRLLMELIGTP 605 Q ++E +GTP Sbjct: 233 QWNKVIEQLGTP 244
>MK10_MOUSE (Q61831) Mitogen-activated protein kinase 10 (EC 2.7.11.24)| (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3) (MAP kinase p49 3F12) Length = 464 Score = 182 bits (461), Expect = 1e-45 Identities = 90/193 (46%), Positives = 133/193 (68%), Gaps = 2/193 (1%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTA--FNDVYIAYELMDTD 206 K++ F N+ AKR RE+ L++ ++H+NI+++ ++ P Q+T F DVY+ ELMD + Sbjct: 94 KLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTP-QKTLEEFQDVYLVMELMDAN 152 Query: 207 LHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGL 386 L Q+I+ L E Y LYQ+L G+K++HSA ++HRDLKPSN+++ ++C LKI DFGL Sbjct: 153 LCQVIQME--LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGL 210 Query: 387 ARTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHV 566 ART + MT YVVTR+YRAPE++L Y +D+WSVGCI E++ K LFPGR ++ Sbjct: 211 ARTAGTSFMMTPYVVTRYYRAPEVILGMG-YKENVDIWSVGCIMGEMVRHKILFPGRSYI 269 Query: 567 HQLRLLMELIGTP 605 Q ++E +GTP Sbjct: 270 DQWNKVIEQLGTP 282
>YPC2_CAEEL (Q11179) Putative serine/threonine-protein kinase C05D10.2 in| chromosome III (EC 2.7.11.24) Length = 470 Score = 181 bits (460), Expect = 1e-45 Identities = 86/206 (41%), Positives = 132/206 (64%), Gaps = 10/206 (4%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMD-HENIVAIRDIIPPAQRTAFNDVYIAYELMDTDL 209 KI +AF N D++RT RE+ L+ H N++ + +I + D+Y+A+E M+ DL Sbjct: 43 KIFDAFRNPTDSQRTFREVMFLQEFGKHPNVIKLYNIF---RADNDRDIYLAFEFMEADL 99 Query: 210 HQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLA 389 H +I+ L + H QY + Q+ R ++++HS NVLHRDLKPSN+LL+A+C +K+ DFGLA Sbjct: 100 HNVIKKGSILKDVHKQYIMCQLFRAIRFLHSGNVLHRDLKPSNVLLDADCRVKLADFGLA 159 Query: 390 RTTSETD---------FMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKP 542 R+ S + +TEYV TRWYR+PE+LL + YT +D+WS+GCI E++ + Sbjct: 160 RSLSSLEDYPEGQKMPDLTEYVATRWYRSPEILLAAKRYTKGVDMWSLGCILAEMLIGRA 219 Query: 543 LFPGRDHVHQLRLLMELIGTPNEADL 620 LFPG ++Q+ +M I P+ AD+ Sbjct: 220 LFPGSSTINQIERIMNTIAKPSRADI 245
>MK08_XENLA (Q8QHK8) Mitogen-activated protein kinase 8 (EC 2.7.11.24)| (Stress-activated protein kinase JNK1) Length = 426 Score = 180 bits (457), Expect = 3e-45 Identities = 88/192 (45%), Positives = 129/192 (67%), Gaps = 1/192 (0%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTA-FNDVYIAYELMDTDL 209 K++ F N+ AKR RE+ L++ ++H+NI+ + ++ P + F D+YI ELMD +L Sbjct: 56 KLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDLYIVMELMDANL 115 Query: 210 HQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLA 389 Q+I+ L E Y LYQ+L G+K++HSA ++HRDLKPSN+++ ++C LKI DFGLA Sbjct: 116 CQVIQME--LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLA 173 Query: 390 RTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVH 569 RT + MT YVVTR+YRAPE++L Y +D+WSVGCI E++ LFPG DH+ Sbjct: 174 RTAGTSFMMTPYVVTRYYRAPEVILGMG-YKENVDIWSVGCILGEMIKGGVLFPGTDHID 232 Query: 570 QLRLLMELIGTP 605 Q ++E +GTP Sbjct: 233 QWNKVIEQLGTP 244
>MK09_HUMAN (P45984) Mitogen-activated protein kinase 9 (EC 2.7.11.24)| (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2) (JNK-55) Length = 424 Score = 178 bits (452), Expect = 1e-44 Identities = 90/194 (46%), Positives = 131/194 (67%), Gaps = 2/194 (1%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTA--FNDVYIAYELMDTD 206 K++ F N+ AKR RE+ LL+ ++H+NI+++ ++ P Q+T F DVY+ ELMD + Sbjct: 56 KLSRPFQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTP-QKTLEEFQDVYLVMELMDAN 114 Query: 207 LHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGL 386 L Q+I + L E Y LYQ+L G+K++HSA ++HRDLKPSN+++ ++C LKI DFGL Sbjct: 115 LCQVI--HMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGL 172 Query: 387 ARTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHV 566 ART MT YVVTR+YRAPE++L Y +D+WSVGCI EL+ +F G DH+ Sbjct: 173 ARTACTNFMMTPYVVTRYYRAPEVILGMG-YKENVDIWSVGCIMGELVKGCVIFQGTDHI 231 Query: 567 HQLRLLMELIGTPN 608 Q ++E +GTP+ Sbjct: 232 DQWNKVIEQLGTPS 245
>MK09_RAT (P49186) Mitogen-activated protein kinase 9 (EC 2.7.11.24)| (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2) (SAPK-alpha) (p54-alpha) Length = 423 Score = 178 bits (452), Expect = 1e-44 Identities = 90/194 (46%), Positives = 131/194 (67%), Gaps = 2/194 (1%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTA--FNDVYIAYELMDTD 206 K++ F N+ AKR RE+ LL+ ++H+NI+++ ++ P Q+T F DVY+ ELMD + Sbjct: 56 KLSRPFQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTP-QKTLEEFQDVYLVMELMDAN 114 Query: 207 LHQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGL 386 L Q+I + L E Y LYQ+L G+K++HSA ++HRDLKPSN+++ ++C LKI DFGL Sbjct: 115 LCQVI--HMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGL 172 Query: 387 ARTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHV 566 ART MT YVVTR+YRAPE++L Y +D+WSVGCI EL+ +F G DH+ Sbjct: 173 ARTACTNFMMTPYVVTRYYRAPEVILGMG-YKENVDIWSVGCIMGELVKGCVIFQGTDHI 231 Query: 567 HQLRLLMELIGTPN 608 Q ++E +GTP+ Sbjct: 232 DQWNKVIEQLGTPS 245
>MK09_CHICK (P79996) Mitogen-activated protein kinase 9 (EC 2.7.11.24)| (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2) Length = 382 Score = 178 bits (451), Expect = 1e-44 Identities = 88/193 (45%), Positives = 129/193 (66%), Gaps = 1/193 (0%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTA-FNDVYIAYELMDTDL 209 K++ F N+ AKR RE+ LL+ ++H+NI+++ ++ P + F DVY+ ELMD +L Sbjct: 56 KLSRPFQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKSLEEFQDVYLVMELMDANL 115 Query: 210 HQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLA 389 Q+I + L E Y LYQ+L G+K++HSA ++HRDLKPSN+++ ++C LKI DFGLA Sbjct: 116 CQVI--HMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLA 173 Query: 390 RTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVH 569 RT MT YVVTR+YRAPE++L Y +D+WSVGCI EL+ +F G DH+ Sbjct: 174 RTACTNFMMTPYVVTRYYRAPEVILGMG-YKENVDIWSVGCIMGELVKGCVIFQGTDHID 232 Query: 570 QLRLLMELIGTPN 608 Q ++E +GTP+ Sbjct: 233 QWNKVIEQLGTPS 245
>MK06_RAT (P27704) Mitogen-activated protein kinase 6 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 3) (ERK-3) (p55-MAPK) Length = 720 Score = 177 bits (449), Expect = 2e-44 Identities = 94/197 (47%), Positives = 128/197 (64%), Gaps = 14/197 (7%) Frame = +3 Query: 69 KRTLREIKLLRHMDHENIVAIRDIIPPA---------QRTAFNDVYIAYELMDTDLHQII 221 K LREIK++R +DH+NIV + +I+ P+ T N VYI E M+TDL ++ Sbjct: 60 KHALREIKIIRRLDHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVL 119 Query: 222 RSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNA-NCDLKICDFGLARTT 398 L EEH + F+YQ+LRGLKYIHSANVLHRDLKP+NL +N + LKI DFGLAR Sbjct: 120 EQGPLL-EEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIM 178 Query: 399 ----SETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHV 566 S ++E +VT+WYR+P LLL+ + YT AID+W+ GCIF E++ K LF G + Sbjct: 179 DPHYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHEL 238 Query: 567 HQLRLLMELIGTPNEAD 617 Q++L++E I +E D Sbjct: 239 EQMQLILESIPVVHEED 255
>MK06_HUMAN (Q16659) Mitogen-activated protein kinase 6 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 3) (ERK-3) (MAP kinase isoform p97) (p97-MAPK) Length = 721 Score = 177 bits (449), Expect = 2e-44 Identities = 94/197 (47%), Positives = 128/197 (64%), Gaps = 14/197 (7%) Frame = +3 Query: 69 KRTLREIKLLRHMDHENIVAIRDIIPPA---------QRTAFNDVYIAYELMDTDLHQII 221 K LREIK++R +DH+NIV + +I+ P+ T N VYI E M+TDL ++ Sbjct: 60 KHALREIKIIRRLDHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVL 119 Query: 222 RSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNA-NCDLKICDFGLARTT 398 L EEH + F+YQ+LRGLKYIHSANVLHRDLKP+NL +N + LKI DFGLAR Sbjct: 120 EQGPLL-EEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIM 178 Query: 399 ----SETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHV 566 S ++E +VT+WYR+P LLL+ + YT AID+W+ GCIF E++ K LF G + Sbjct: 179 DPHYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHEL 238 Query: 567 HQLRLLMELIGTPNEAD 617 Q++L++E I +E D Sbjct: 239 EQMQLILESIPVVHEED 255
>MK06_MOUSE (Q61532) Mitogen-activated protein kinase 6 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 3) (ERK-3) Length = 720 Score = 176 bits (446), Expect = 5e-44 Identities = 93/197 (47%), Positives = 128/197 (64%), Gaps = 14/197 (7%) Frame = +3 Query: 69 KRTLREIKLLRHMDHENIVAIRDIIPPA---------QRTAFNDVYIAYELMDTDLHQII 221 K LREIK++R +DH+NIV + +I+ P+ T N VYI E M+TDL ++ Sbjct: 60 KHALREIKIIRRLDHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVL 119 Query: 222 RSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNA-NCDLKICDFGLARTT 398 L EEH + F+YQ+LRGLKYIHSANVLHRDLKP+NL +N + LKI DFGLAR Sbjct: 120 EQGPLL-EEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIM 178 Query: 399 ----SETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHV 566 S ++E +VT+WYR+P LLL+ + YT AID+W+ GCIF E++ K LF G + Sbjct: 179 DPHYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHEL 238 Query: 567 HQLRLLMELIGTPNEAD 617 Q++L+++ I +E D Sbjct: 239 EQMQLILDSIPVVHEED 255
>PMK3_CAEEL (O44514) Mitogen-activated protein kinase pmk-3 (EC 2.7.11.24) (p38| MAP kinase 3) (Stress-activated protein kinase pmk-3) Length = 474 Score = 172 bits (436), Expect = 8e-43 Identities = 91/211 (43%), Positives = 132/211 (62%), Gaps = 8/211 (3%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLH 212 K+ F + A+R RE KLL+ M H+NI+ DI P + F DVY+ E L+ Sbjct: 151 KMREPFFDPHHARRIFRETKLLQLMRHDNIICALDIYTPDEENDFRDVYVVTEFAGRSLY 210 Query: 213 QIIRSNQ-----ALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICD 377 QI++ + L++EH ++ +YQI+R LKYIHSAN++HRDLKP NL L + DL I D Sbjct: 211 QILKQQRDYGRRVLTDEHIKFIIYQIIRALKYIHSANIIHRDLKPGNLALTDDSDLMILD 270 Query: 378 FGLARTTSETD-FMTEYVVTRWYRAPELLL-NSSEYTAAIDVWSVGCIFMELMDRKPLFP 551 FGLAR+ + D +T+YV TRWYR+PE++ YT D+WS+GCI EL+ +PLFP Sbjct: 271 FGLARSLEKKDTSLTQYVQTRWYRSPEVIYWKIDSYTNLADMWSLGCIAAELLTGEPLFP 330 Query: 552 GRDHVHQLRLLMELIGTPNEADLDFV-NENA 641 G + Q + + +L G+P+E L + N+N+ Sbjct: 331 GDEPNAQYQRITQLCGSPDEELLTKIENDNS 361
>MK04_HUMAN (P31152) Mitogen-activated protein kinase 4 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 4) (ERK-4) (MAP kinase isoform p63) (p63-MAPK) Length = 557 Score = 171 bits (434), Expect = 1e-42 Identities = 88/196 (44%), Positives = 129/196 (65%), Gaps = 11/196 (5%) Frame = +3 Query: 69 KRTLREIKLLRHMDHENIVAIRDIIPP------AQRTAFNDVYIAYELMDTDLHQIIRSN 230 K LREIK++R +DH+NIV + +++ P + F+ YI E M+TDL +++ Sbjct: 60 KHALREIKIIRRLDHDNIVKVYEVLGPKGTDLQGELFKFSVAYIVQEYMETDLARLLEQG 119 Query: 231 QALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNA-NCDLKICDFGLARTT--- 398 L+EEH + F+YQ+LRGLKYIHSANVLHRDLKP+N+ ++ + LKI DFGLAR Sbjct: 120 -TLAEEHAKLFMYQLLRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLARIVDQH 178 Query: 399 -SETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQL 575 S +++E +VT+WYR+P LLL+ + YT AID+W+ GCI E++ + LF G + Q+ Sbjct: 179 YSHKGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGRMLFAGAHELEQM 238 Query: 576 RLLMELIGTPNEADLD 623 +L++E I E D D Sbjct: 239 QLILETIPVIREEDKD 254
>MK04_RAT (Q63454) Mitogen-activated protein kinase 4 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 4) (ERK-4) (MAP kinase isoform p63) (p63-MAPK) (MNK2) (Fragment) Length = 274 Score = 169 bits (427), Expect = 8e-42 Identities = 87/194 (44%), Positives = 127/194 (65%), Gaps = 11/194 (5%) Frame = +3 Query: 69 KRTLREIKLLRHMDHENIVAIRDIIPP------AQRTAFNDVYIAYELMDTDLHQIIRSN 230 K LREIK++R +DH+NIV + +++ P + F+ YI E M+TDL ++ Sbjct: 34 KHALREIKIIRRLDHDNIVKVYEVLGPKGSDLQGELFKFSVAYIVQEYMETDLACLLEQG 93 Query: 231 QALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNA-NCDLKICDFGLARTT--- 398 L+EEH + F+YQ+LRGLKYIHSANVLHRDLKP+N+ ++ + LKI DFGLAR Sbjct: 94 -TLTEEHAKLFMYQLLRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLARIADQH 152 Query: 399 -SETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQL 575 S +++E +VT+WYR+P LLL+ + YT AID+W+ GCI E++ K LF G + Q+ Sbjct: 153 YSHKGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGKMLFAGAHELEQM 212 Query: 576 RLLMELIGTPNEAD 617 +L+++ I E D Sbjct: 213 QLILDTIPVVREED 226
>MK04_MOUSE (Q6P5G0) Mitogen-activated protein kinase 4 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 4) (ERK-4) Length = 583 Score = 167 bits (424), Expect = 2e-41 Identities = 86/194 (44%), Positives = 127/194 (65%), Gaps = 11/194 (5%) Frame = +3 Query: 69 KRTLREIKLLRHMDHENIVAIRDIIPP------AQRTAFNDVYIAYELMDTDLHQIIRSN 230 K LREIK++R +DH+NIV + +++ P + F+ YI E M+TDL ++ Sbjct: 60 KHALREIKIIRRLDHDNIVKVYEVLGPKGSDLQGELFKFSVAYIVQEYMETDLACLLEQG 119 Query: 231 QALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNA-NCDLKICDFGLARTT--- 398 L+E+H + F+YQ+LRGLKYIHSANVLHRDLKP+N+ ++ + LKI DFGLAR Sbjct: 120 -TLTEDHAKLFMYQLLRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLARIVDQH 178 Query: 399 -SETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQL 575 S +++E +VT+WYR+P LLL+ + YT AID+W+ GCI E++ K LF G + Q+ Sbjct: 179 YSHKGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGKMLFAGAHELEQM 238 Query: 576 RLLMELIGTPNEAD 617 +L+++ I E D Sbjct: 239 QLILDTIPVVREED 252
>CDC2B_ANTMA (Q38773) Cell division control protein 2 homolog B (EC 2.7.11.22)| (EC 2.7.11.23) (Fragment) Length = 280 Score = 161 bits (407), Expect = 2e-39 Identities = 85/182 (46%), Positives = 118/182 (64%), Gaps = 4/182 (2%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRSNQALSEE--H 251 +REI LL+ M HENIV ++D++ +R +Y+ +E +D DL + + S S++ Sbjct: 36 IREISLLKEMHHENIVNLKDVVHREKR-----LYLVFEYLDLDLKKHMDSCPEFSQDLHM 90 Query: 252 CQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCD-LKICDFGLARTTS-ETDFMTEY 425 + FL QILRG+ Y HS VLHRDLKP NLL++ + +K+ DFGLAR T Sbjct: 91 VKMFLCQILRGVAYCHSHRVLHRDLKPQNLLIDRGSNTIKLADFGLARAFGIPVRTFTHE 150 Query: 426 VVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTP 605 VVT WYRAPE+LL S Y+ +DVWSVGCIF E++++KPLFPG + +L + +IGTP Sbjct: 151 VVTLWYRAPEVLLGSRHYSTPVDVWSVGCIFAEMVNQKPLFPGDSEIDELHKIFRIIGTP 210 Query: 606 NE 611 NE Sbjct: 211 NE 212
>CDC2A_ANTMA (Q38772) Cell division control protein 2 homolog A (EC 2.7.11.22)| (EC 2.7.11.23) Length = 294 Score = 160 bits (405), Expect = 3e-39 Identities = 84/182 (46%), Positives = 118/182 (64%), Gaps = 4/182 (2%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRSNQALSEEH-- 251 +REI LL+ M H NIV ++D++ +R +Y+ +E +D DL + + S S++ Sbjct: 49 IREISLLKEMQHGNIVRLQDVVHSEKR-----LYLVFEYLDLDLKKHMDSCPEFSQDPRL 103 Query: 252 CQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCD-LKICDFGLARTTS-ETDFMTEY 425 + FLYQILRG+ Y HS VLHRDLKP NLL++ + LK+ DFGLAR T Sbjct: 104 VKMFLYQILRGIAYCHSHRVLHRDLKPQNLLIDRRTNALKLADFGLARAFGIPVRTFTHE 163 Query: 426 VVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTP 605 VVT WYRAPE+LL S Y+ +DVWSVGCIF E+++++PLFPG + +L + ++GTP Sbjct: 164 VVTLWYRAPEILLGSRHYSTPVDVWSVGCIFAEMVNQRPLFPGDSEIDELFKIFRVMGTP 223 Query: 606 NE 611 NE Sbjct: 224 NE 225
>PHO85_YARLI (Q6C7U8) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 294 Score = 160 bits (404), Expect = 4e-39 Identities = 81/183 (44%), Positives = 117/183 (63%), Gaps = 4/183 (2%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRSNQ---ALSEE 248 +REI L++ + HENIV + D+I N + + +E MD DL + + +N AL + Sbjct: 51 IREISLMKELKHENIVTLYDVIHTE-----NKLNLVFEYMDKDLKKFMDTNGNKGALETK 105 Query: 249 HCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEY 425 ++F+YQ+LRG+ + H VLHRDLKP NLL+NA LK+ DFGLAR + + Sbjct: 106 QVKWFMYQLLRGILFCHDNRVLHRDLKPQNLLINAKGQLKLADFGLARAFGIPVNTFSNE 165 Query: 426 VVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTP 605 VVT WYRAP++LL S Y+ +ID+WS GCI E+ +PLFPG + QL+ + +L+GTP Sbjct: 166 VVTLWYRAPDVLLGSRTYSTSIDIWSAGCIMAEMFTGRPLFPGSSNDDQLQHIFKLMGTP 225 Query: 606 NEA 614 NE+ Sbjct: 226 NES 228
>CDC2_VIGAC (Q41639) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 160 bits (404), Expect = 4e-39 Identities = 84/182 (46%), Positives = 117/182 (64%), Gaps = 4/182 (2%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRSNQALSEEHCQ 257 +REI LL+ M H NIV ++D++ +R +Y+ +E +D DL + + S+ ++ Q Sbjct: 49 IREISLLKEMQHRNIVRLQDVVHSEKR-----LYLVFEYLDLDLKKHMDSSPEFVKDPRQ 103 Query: 258 Y--FLYQILRGLKYIHSANVLHRDLKPSNLLLNANCD-LKICDFGLARTTS-ETDFMTEY 425 FLYQIL G+ Y HS VLHRDLKP NLL++ + LK+ DFGLAR T Sbjct: 104 VKMFLYQILCGIAYCHSHRVLHRDLKPQNLLIDRRTNSLKLADFGLARAFGIPVRTFTHE 163 Query: 426 VVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTP 605 VVT WYRAPE+LL S Y+ +DVWSVGCIF E+++R+PLFPG + +L + ++GTP Sbjct: 164 VVTLWYRAPEILLGSRHYSTPVDVWSVGCIFAEMVNRRPLFPGDSEIDELFKIFRILGTP 223 Query: 606 NE 611 NE Sbjct: 224 NE 225
>CDC22_MEDSA (Q05006) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| Length = 294 Score = 159 bits (403), Expect = 5e-39 Identities = 82/182 (45%), Positives = 118/182 (64%), Gaps = 4/182 (2%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRSNQALSEEHCQ 257 +REI LL+ M H NIV ++D++ +R +Y+ +E +D DL + + S+ +++ Q Sbjct: 49 IREISLLKEMQHRNIVRLQDVVHSEKR-----LYLVFEYLDLDLKKFMDSSPEFAKDQRQ 103 Query: 258 Y--FLYQILRGLKYIHSANVLHRDLKPSNLLLNANCD-LKICDFGLARTTS-ETDFMTEY 425 FLYQIL G+ Y HS VLHRDLKP NLL++ + + +K+ DFGLAR T Sbjct: 104 IKMFLYQILCGIAYCHSHRVLHRDLKPQNLLIDRSSNAVKLADFGLARAFGIPVRTFTHE 163 Query: 426 VVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTP 605 VVT WYRAPE+LL S Y+ +DVWSVGCIF E+++++PLFPG + +L + + GTP Sbjct: 164 VVTLWYRAPEILLGSRHYSTPVDVWSVGCIFAEMINQRPLFPGDSEIDELFKIFRITGTP 223 Query: 606 NE 611 NE Sbjct: 224 NE 225
>PCTK2_RAT (O35831) Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 2) Length = 523 Score = 159 bits (402), Expect = 7e-39 Identities = 84/189 (44%), Positives = 115/189 (60%), Gaps = 2/189 (1%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRS-NQALSEEHC 254 +RE+ LL+ + H NIV + DI+ + + + +E +D DL Q + +S + Sbjct: 236 IREVSLLKDLKHANIVTLHDIVHTDK-----SLTLVFEYLDKDLKQYMDDCGSIMSMHNV 290 Query: 255 QYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEYVV 431 + FLYQILRGL Y H VLHRDLKP NLL+N +LK+ DFGLAR S T + VV Sbjct: 291 KLFLYQILRGLAYCHRRKVLHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVV 350 Query: 432 TRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPNE 611 T WYR P++LL SSEY+ ID+W VGCIF E+ +PLFPG +L L+ L+GTP++ Sbjct: 351 TLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQ 410 Query: 612 ADLDFVNEN 638 V+ N Sbjct: 411 ETWPGVSSN 419
>PCTK2_MOUSE (Q8K0D0) Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 2) Length = 523 Score = 159 bits (402), Expect = 7e-39 Identities = 84/189 (44%), Positives = 115/189 (60%), Gaps = 2/189 (1%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRS-NQALSEEHC 254 +RE+ LL+ + H NIV + DI+ + + + +E +D DL Q + +S + Sbjct: 236 IREVSLLKDLKHANIVTLHDIVHTDK-----SLTLVFEYLDKDLKQYMDDCGNIMSMHNV 290 Query: 255 QYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEYVV 431 + FLYQILRGL Y H VLHRDLKP NLL+N +LK+ DFGLAR S T + VV Sbjct: 291 KLFLYQILRGLAYCHRRKVLHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVV 350 Query: 432 TRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPNE 611 T WYR P++LL SSEY+ ID+W VGCIF E+ +PLFPG +L L+ L+GTP++ Sbjct: 351 TLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQ 410 Query: 612 ADLDFVNEN 638 V+ N Sbjct: 411 ETWPGVSSN 419
>CDC2_VIGUN (P52389) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 159 bits (402), Expect = 7e-39 Identities = 83/182 (45%), Positives = 117/182 (64%), Gaps = 4/182 (2%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRSNQALSEEHCQ 257 +REI LL+ M H NIV ++D++ +R +Y+ +E +D DL + + S+ ++ Q Sbjct: 49 IREISLLKEMQHRNIVRLQDVVHSEKR-----LYLVFEYLDLDLKKHMDSSPEFVKDPRQ 103 Query: 258 Y--FLYQILRGLKYIHSANVLHRDLKPSNLLLNANCD-LKICDFGLARTTS-ETDFMTEY 425 FLYQIL G+ Y HS VLHRDLKP NLL++ + LK+ DFGLAR T Sbjct: 104 VKMFLYQILCGIAYCHSHRVLHRDLKPQNLLIDRRTNSLKLADFGLARAFGIPVRTFTHE 163 Query: 426 VVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTP 605 VVT WYRAPE+LL S Y+ +DVWSVGC+F E+++R+PLFPG + +L + ++GTP Sbjct: 164 VVTLWYRAPEILLGSRHYSTPVDVWSVGCLFAEMVNRRPLFPGDSEIDELFKIFRILGTP 223 Query: 606 NE 611 NE Sbjct: 224 NE 225
>CDC2_CHERU (P93101) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 159 bits (402), Expect = 7e-39 Identities = 85/182 (46%), Positives = 116/182 (63%), Gaps = 4/182 (2%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRS--NQALSEEH 251 +REI LL+ M H NIV ++D++ +R +Y+ +E +D DL + + S + A Sbjct: 49 IREISLLKEMQHGNIVRLQDVVHSEKR-----LYLVFEYLDLDLKKHMDSCPDFAKDPRM 103 Query: 252 CQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCD-LKICDFGLARTTS-ETDFMTEY 425 + FLYQILRG+ Y HS VLHRDLKP NLL++ + LK+ DFGLAR T Sbjct: 104 IKRFLYQILRGIAYCHSHRVLHRDLKPQNLLIDRQTNALKLADFGLARAFGIPVRTFTHE 163 Query: 426 VVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTP 605 VVT WYRAPE+LL S Y+ +DVWSVGCIF E++++KPLFPG + +L + +GTP Sbjct: 164 VVTLWYRAPEILLGSRHYSTPVDVWSVGCIFAEMVNQKPLFPGDSEIDELFKIFRTLGTP 223 Query: 606 NE 611 NE Sbjct: 224 NE 225
>PCTK2_HUMAN (Q00537) Serine/threonine-protein kinase PCTAIRE-2 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 2) Length = 523 Score = 159 bits (401), Expect = 9e-39 Identities = 83/189 (43%), Positives = 115/189 (60%), Gaps = 2/189 (1%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRS-NQALSEEHC 254 +RE+ LL+ + H NIV + DI+ + + + +E +D DL Q + +S + Sbjct: 236 IREVSLLKDLKHANIVTLHDIVHTDK-----SLTLVFEYLDKDLKQYMDDCGNIMSMHNV 290 Query: 255 QYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEYVV 431 + FLYQILRGL Y H VLHRDLKP NLL+N +LK+ DFGLAR S T + VV Sbjct: 291 KLFLYQILRGLAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVV 350 Query: 432 TRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPNE 611 T WYR P++LL SSEY+ ID+W VGCIF E+ +PLFPG +L L+ L+GTP++ Sbjct: 351 TLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQ 410 Query: 612 ADLDFVNEN 638 ++ N Sbjct: 411 ETWPGISSN 419
>CDC2A_ARATH (P24100) Cell division control protein 2 homolog A (EC 2.7.11.22)| (EC 2.7.11.23) Length = 294 Score = 159 bits (401), Expect = 9e-39 Identities = 83/182 (45%), Positives = 116/182 (63%), Gaps = 4/182 (2%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRSNQALSEE--H 251 +REI LL+ M H NIV ++D++ +R +Y+ +E +D DL + + S S++ Sbjct: 49 IREISLLKEMQHSNIVKLQDVVHSEKR-----LYLVFEYLDLDLKKHMDSTPDFSKDLHM 103 Query: 252 CQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCD-LKICDFGLARTTS-ETDFMTEY 425 + +LYQILRG+ Y HS VLHRDLKP NLL++ + LK+ DFGLAR T Sbjct: 104 IKTYLYQILRGIAYCHSHRVLHRDLKPQNLLIDRRTNSLKLADFGLARAFGIPVRTFTHE 163 Query: 426 VVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTP 605 VVT WYRAPE+LL S Y+ +D+WSVGCIF E++ +KPLFPG + QL + ++GTP Sbjct: 164 VVTLWYRAPEILLGSHHYSTPVDIWSVGCIFAEMISQKPLFPGDSEIDQLFKIFRIMGTP 223 Query: 606 NE 611 E Sbjct: 224 YE 225
>CDC21_ORYSA (P29618) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| Length = 294 Score = 159 bits (401), Expect = 9e-39 Identities = 83/182 (45%), Positives = 117/182 (64%), Gaps = 4/182 (2%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRSNQALSEEHC- 254 +REI LL+ M H NIV + D+I +R +Y+ +E +D DL + + S ++ Sbjct: 49 IREISLLKEMHHGNIVRLHDVIHSEKR-----IYLVFEYLDLDLKKFMDSCPEFAKNPTL 103 Query: 255 -QYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCD-LKICDFGLARTTS-ETDFMTEY 425 + +LYQILRG+ Y HS VLHRDLKP NLL++ + LK+ DFGLAR T Sbjct: 104 IKSYLYQILRGVAYCHSHRVLHRDLKPQNLLIDRRTNALKLADFGLARAFGIPVRTFTHE 163 Query: 426 VVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTP 605 VVT WYRAPE+LL S +Y+ +D+WSVGCIF E++++KPLFPG + +L + ++GTP Sbjct: 164 VVTLWYRAPEILLGSRQYSTPVDMWSVGCIFAEMVNQKPLFPGDSEIDELFKIFRVLGTP 223 Query: 606 NE 611 NE Sbjct: 224 NE 225
>CDC2_MAIZE (P23111) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34cdc2) Length = 294 Score = 157 bits (398), Expect = 2e-38 Identities = 81/182 (44%), Positives = 117/182 (64%), Gaps = 4/182 (2%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRSNQALSEEHC- 254 +REI LL+ M+H NIV + D++ +R +Y+ +E +D DL + + S ++ Sbjct: 49 IREISLLKEMNHGNIVRLHDVVHSEKR-----IYLVFEYLDLDLKKFMDSCPEFAKNPTL 103 Query: 255 -QYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCD-LKICDFGLARTTS-ETDFMTEY 425 + +LYQIL G+ Y HS VLHRDLKP NLL++ + LK+ DFGLAR T Sbjct: 104 IKSYLYQILHGVAYCHSHRVLHRDLKPQNLLIDRRTNALKLADFGLARAFGIPVRTFTHE 163 Query: 426 VVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTP 605 VVT WYRAPE+LL + +Y+ +DVWSVGCIF E++++KPLFPG + +L + ++GTP Sbjct: 164 VVTLWYRAPEILLGARQYSTPVDVWSVGCIFAEMVNQKPLFPGDSEIDELFKIFRILGTP 223 Query: 606 NE 611 NE Sbjct: 224 NE 225
>CDC22_ORYSA (P29619) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| Length = 292 Score = 157 bits (396), Expect = 3e-38 Identities = 81/181 (44%), Positives = 115/181 (63%), Gaps = 3/181 (1%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRSNQALSEEHC- 254 +REI LL+ M H NIV ++D++ + +Y+ +E +D DL + + S+ Sbjct: 49 IREISLLKEMQHRNIVRLQDVVHKEKC-----IYLVFEYLDLDLKKHMDSSPDFKNHRIV 103 Query: 255 QYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCD-LKICDFGLARTTS-ETDFMTEYV 428 + FLYQILRG+ Y HS VLHRDLKP NLL++ + LK+ DFGLAR T V Sbjct: 104 KSFLYQILRGIAYCHSHRVLHRDLKPQNLLIDRRTNSLKLADFGLARAFGIPVRTFTHEV 163 Query: 429 VTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPN 608 VT WYRAPE+LL + Y+ +D+WSVGCIF E++++KPLFPG + +L + ++GTPN Sbjct: 164 VTLWYRAPEILLGARHYSTPVDMWSVGCIFAEMVNQKPLFPGDSEIDELFKIFSIMGTPN 223 Query: 609 E 611 E Sbjct: 224 E 224
>PHO85_DEBHA (Q6BRY2) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 330 Score = 157 bits (396), Expect = 3e-38 Identities = 84/182 (46%), Positives = 117/182 (64%), Gaps = 4/182 (2%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRS--NQ-ALSEE 248 +REI L++ +DHENIV + D+I N + + +E MD DL + + + NQ AL + Sbjct: 52 IREISLMKELDHENIVTLYDVIHTE-----NKLTLVFEFMDKDLKKYMEAHGNQGALDLK 106 Query: 249 HCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEY 425 + F++Q+L+G+ + H VLHRDLKP NLL+N +LK+ DFGLAR + + Sbjct: 107 IVKSFIFQLLKGIMFCHDNRVLHRDLKPQNLLINNKGELKLGDFGLARAFGIPFNTFSNE 166 Query: 426 VVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTP 605 VVT WYRAP++LL S YTA+ID+WS GCIF E+ KPLFPG + QL + L+GTP Sbjct: 167 VVTLWYRAPDVLLGSRAYTASIDIWSAGCIFAEMCTGKPLFPGTSNDDQLIKIFRLMGTP 226 Query: 606 NE 611 NE Sbjct: 227 NE 228
>CDC2_DICDI (P34112) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 296 Score = 156 bits (394), Expect = 6e-38 Identities = 77/180 (42%), Positives = 116/180 (64%), Gaps = 1/180 (0%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRSNQALSEEHCQ 257 LREI LL+ + H N+V++ D++ R +Y+ +E +D DL + + S AL + + Sbjct: 53 LREISLLKEVPHPNVVSLFDVLHCQNR-----LYLVFEYLDQDLKKYMDSVPALCPQLIK 107 Query: 258 YFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEYVVT 434 +LYQ+L+GL Y H +LHRDLKP NLL++ LK+ DFGLAR S T +VT Sbjct: 108 SYLYQLLKGLAYSHGHRILHRDLKPQNLLIDRQGALKLADFGLARAVSIPVRVYTHEIVT 167 Query: 435 RWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPNEA 614 WYRAPE+LL S Y+ +D+WSVGCIF E++++KPLF G + Q+ + ++GTP+++ Sbjct: 168 LWYRAPEVLLGSKSYSVPVDMWSVGCIFGEMLNKKPLFSGDCEIDQIFRIFRVLGTPDDS 227
>CDC28_CANAL (P43063) Cell division control protein 28 (EC 2.7.11.22)| Length = 317 Score = 155 bits (391), Expect = 1e-37 Identities = 79/182 (43%), Positives = 114/182 (62%), Gaps = 4/182 (2%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRS---NQALSEE 248 +REI LL+ M +NIV + DII + + +Y+ +E +D DL + + S L Sbjct: 53 IREISLLKEMKDDNIVRLYDII----HSDSHKLYLVFEFLDLDLKKYMESIPQGVGLGAN 108 Query: 249 HCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEY 425 + F+ Q++RG+K+ HS VLHRDLKP NLL++ +LK+ DFGLAR T Sbjct: 109 MIKRFMNQLIRGIKHCHSHRVLHRDLKPQNLLIDKEGNLKLADFGLARAFGVPLRAYTHE 168 Query: 426 VVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTP 605 VVT WYRAPE+LL +Y+ +D+WSVGCIF E+ +RKPLFPG + ++ + ++GTP Sbjct: 169 VVTLWYRAPEILLGGKQYSTGVDMWSVGCIFAEMCNRKPLFPGDSEIDEIFRIFRILGTP 228 Query: 606 NE 611 NE Sbjct: 229 NE 230
>CDK2_CARAU (P43450) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 154 bits (390), Expect = 2e-37 Identities = 79/182 (43%), Positives = 115/182 (63%), Gaps = 3/182 (1%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRSNQA--LSEEH 251 +REI LL+ ++H NIV + D+I N +Y+ +E + DL + + S+ +S Sbjct: 49 IREISLLKELNHPNIVKLHDVIHTE-----NKLYLVFEFLHQDLKRFMDSSTVTGISLPL 103 Query: 252 CQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEYV 428 + +L+Q+L+GL + HS VLHRDLKP NLL+NA ++K+ DFGLAR T V Sbjct: 104 VKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINAQGEIKLADFGLARAFGVPVRTYTHEV 163 Query: 429 VTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPN 608 VT WYRAPE+LL Y+ A+D+WS+GCIF E++ RK LFPG + QL + +GTP+ Sbjct: 164 VTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMITRKALFPGDSEIDQLFRIFRTLGTPD 223 Query: 609 EA 614 E+ Sbjct: 224 ES 225
>CDC2H_THEAN (Q26671) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 298 Score = 154 bits (390), Expect = 2e-37 Identities = 79/179 (44%), Positives = 114/179 (63%), Gaps = 2/179 (1%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRS-NQALSEEHC 254 +REI LL+ + H NIV +RD+I + + +E +D DL +++ + + L Sbjct: 48 IREISLLKELHHPNIVWLRDVIHSEKCLT-----LVFEYLDQDLKKLLDACDGGLEPTTA 102 Query: 255 QYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEYVV 431 + FLYQILRG+ Y H +LHRDLKP NLL+N LK+ DFGLAR + T VV Sbjct: 103 KSFLYQILRGISYCHDHRILHRDLKPQNLLINREGVLKLADFGLARAFAIPVRSYTHEVV 162 Query: 432 TRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPN 608 T WYRAP++L+ S +Y+ A+D+WSVGCIF E+++ PLFPG QL+ + +++GTPN Sbjct: 163 TLWYRAPDVLMGSKKYSTAVDIWSVGCIFAEMINGVPLFPGISEQDQLKRIFKILGTPN 221
>CDC21_MEDSA (P24923) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (Fragment) Length = 291 Score = 154 bits (390), Expect = 2e-37 Identities = 82/182 (45%), Positives = 115/182 (63%), Gaps = 4/182 (2%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRSNQALSEEHCQ 257 +REI LL+ M H NIV ++D++ +R +Y+ +E +D DL + + S+ ++ Q Sbjct: 46 IREISLLKEMQHRNIVRLQDVVHSDKR-----LYLVFEYLDLDLKKHMDSSPEFIKDPRQ 100 Query: 258 Y--FLYQILRGLKYIHSANVLHRDLKPSNLLLNANCD-LKICDFGLARTTS-ETDFMTEY 425 FLYQ+L G+ Y HS VLHRDLKP NLL++ + LK+ DFGLAR T Sbjct: 101 VKMFLYQMLCGIAYCHSHRVLHRDLKPQNLLIDRRTNSLKLADFGLARAFGIPVRTFTHE 160 Query: 426 VVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTP 605 VVT WYRAPE+LL S Y+ +DVWSVGCIF E+ +R+PL PG + +L + ++GTP Sbjct: 161 VVTLWYRAPEILLGSRHYSTPVDVWSVGCIFAEMANRRPLSPGDSEIDELFKIFRILGTP 220 Query: 606 NE 611 NE Sbjct: 221 NE 222
>PHO85_CANAL (Q9HGY5) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) (CaPHO85) Length = 326 Score = 154 bits (389), Expect = 2e-37 Identities = 81/182 (44%), Positives = 113/182 (62%), Gaps = 4/182 (2%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIR---SNQALSEE 248 +REI L++ +DHENIV + D+I N + + +E MD DL + + AL + Sbjct: 52 IREISLMKELDHENIVTLYDVIHTE-----NKLTLVFEYMDKDLKKYMEVHGQQSALDLK 106 Query: 249 HCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEY 425 + F++Q+L+G+ + H VLHRDLKP NLL+N +LK+ DFGLAR + + Sbjct: 107 VVKSFMFQLLKGIMFCHDNRVLHRDLKPQNLLINNKGELKLGDFGLARAFGIPFNTFSNE 166 Query: 426 VVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTP 605 VVT WYRAP++LL S YT +ID+WS GCIF E+ KPLFPG + QL + L+GTP Sbjct: 167 VVTLWYRAPDVLLGSRAYTTSIDIWSAGCIFAEMCTGKPLFPGTANEDQLIKIFRLMGTP 226 Query: 606 NE 611 NE Sbjct: 227 NE 228
>PCTK1_MOUSE (Q04735) Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 1) (CRK5) Length = 496 Score = 153 bits (387), Expect = 4e-37 Identities = 78/180 (43%), Positives = 110/180 (61%), Gaps = 2/180 (1%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRS-NQALSEEHC 254 +RE+ LL+ + H NIV + DII + + + +E +D DL Q + ++ + Sbjct: 209 IREVSLLKDLKHANIVTLHDIIHTEK-----SLTLVFEYLDKDLKQYLDDCGNVINMHNV 263 Query: 255 QYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEYVV 431 + FL+Q+LRGL Y H VLHRDLKP NLL+N +LK+ DFGLAR S T + VV Sbjct: 264 KLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVV 323 Query: 432 TRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPNE 611 T WYR P++LL S++Y+ ID+W VGCIF E+ +PLFPG QL + ++GTP E Sbjct: 324 TLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTE 383
>CDKL2_RABIT (Q9TTK0) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIAMRE) Length = 566 Score = 153 bits (387), Expect = 4e-37 Identities = 78/204 (38%), Positives = 126/204 (61%), Gaps = 4/204 (1%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMD-TDL 209 K + D+K+ K +REIKLL+ + HEN+V + ++ +R Y+ +E +D T L Sbjct: 34 KFLESDDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKKKKRW-----YLVFEFVDHTIL 88 Query: 210 HQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLA 389 + L ++ Q +L+QI+ G+ + HS N++HRD+KP N+L++ + +K+CDFG A Sbjct: 89 DDLELFPNGLDDQVVQKYLFQIINGIGFCHSHNIIHRDIKPENILVSQSGVVKLCDFGFA 148 Query: 390 RTTSET-DFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHV 566 RT + + T+YV TRWYRAPELL+ +Y A+DVW++GC+ E++ +PLFPG + Sbjct: 149 RTLAAPGEVYTDYVATRWYRAPELLVGDVKYGKAVDVWAIGCLVTEMLMGEPLFPGDSDI 208 Query: 567 HQLRLLMELIGT--PNEADLDFVN 632 QL L+M +G P +L + N Sbjct: 209 DQLYLIMRCLGNLIPRHQELFYKN 232
>CDC2H_PLAKH (O96821) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 153 bits (386), Expect = 5e-37 Identities = 80/188 (42%), Positives = 114/188 (60%), Gaps = 2/188 (1%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIR-SNQALSEEHC 254 +REI +L+ + H NIV + D+I +R + + +E +D DL +++ + L Sbjct: 48 IREISILKELKHSNIVKLYDVIHTKKR-----LILVFEHLDQDLKKLLDVCDGGLESVTA 102 Query: 255 QYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEYVV 431 + FL Q+L G+ Y H VLHRDLKP NLL+N +LKI DFGLAR T VV Sbjct: 103 KSFLLQLLSGIAYCHEHRVLHRDLKPQNLLINREGELKIADFGLARAFGIPVRKYTHEVV 162 Query: 432 TRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPNE 611 T WYRAP++L+ S +Y+ ID+WSVGCIF E+++ +PLFPG QL + ++GTPN Sbjct: 163 TLWYRAPDILMGSKKYSTPIDIWSVGCIFAEMVNGRPLFPGVSETDQLMRIFRILGTPNS 222 Query: 612 ADLDFVNE 635 A+ V E Sbjct: 223 ANWPSVTE 230
>PCTK3_PONPY (Q5RD01) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 472 Score = 153 bits (386), Expect = 5e-37 Identities = 77/180 (42%), Positives = 112/180 (62%), Gaps = 2/180 (1%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQII-RSNQALSEEHC 254 +RE+ LL+++ H NIV + D+I + + + +E +D+DL Q + +S + Sbjct: 186 IREVSLLKNLKHANIVTLHDLIHTDR-----SLTLVFEYLDSDLKQYLDHCGNLMSMHNV 240 Query: 255 QYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEYVV 431 + F++Q+LRGL Y H +LHRDLKP NLL+N +LK+ DFGLAR S T + VV Sbjct: 241 KIFMFQLLRGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVV 300 Query: 432 TRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPNE 611 T WYR P++LL S+EY+ ID+W VGCI E+ +PLFPG +L L+ L+GTP E Sbjct: 301 TLWYRPPDVLLGSTEYSTPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTE 360
>PCTK3_HUMAN (Q07002) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 472 Score = 153 bits (386), Expect = 5e-37 Identities = 77/180 (42%), Positives = 112/180 (62%), Gaps = 2/180 (1%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQII-RSNQALSEEHC 254 +RE+ LL+++ H NIV + D+I + + + +E +D+DL Q + +S + Sbjct: 186 IREVSLLKNLKHANIVTLHDLIHTDR-----SLTLVFEYLDSDLKQYLDHCGNLMSMHNV 240 Query: 255 QYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEYVV 431 + F++Q+LRGL Y H +LHRDLKP NLL+N +LK+ DFGLAR S T + VV Sbjct: 241 KIFMFQLLRGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVV 300 Query: 432 TRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPNE 611 T WYR P++LL S+EY+ ID+W VGCI E+ +PLFPG +L L+ L+GTP E Sbjct: 301 TLWYRPPDVLLGSTEYSTPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTE 360
>PCTK1_HUMAN (Q00536) Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 1) Length = 496 Score = 153 bits (386), Expect = 5e-37 Identities = 78/180 (43%), Positives = 110/180 (61%), Gaps = 2/180 (1%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRS-NQALSEEHC 254 +RE+ LL+ + H NIV + DII + + + +E +D DL Q + ++ + Sbjct: 209 IREVSLLKDLKHANIVTLHDIIHTEK-----SLTLVFEYLDKDLKQYLDDCGNIINMHNV 263 Query: 255 QYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEYVV 431 + FL+Q+LRGL Y H VLHRDLKP NLL+N +LK+ DFGLAR S T + VV Sbjct: 264 KLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVV 323 Query: 432 TRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPNE 611 T WYR P++LL S++Y+ ID+W VGCIF E+ +PLFPG QL + ++GTP E Sbjct: 324 TLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTE 383
>PHO85_YEAST (P17157) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 305 Score = 153 bits (386), Expect = 5e-37 Identities = 78/186 (41%), Positives = 115/186 (61%), Gaps = 7/186 (3%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRSN------QAL 239 +REI L++ + HENIV + D+I N + + +E MD DL + + S + L Sbjct: 51 IREISLMKELKHENIVRLYDVIHTE-----NKLTLVFEFMDNDLKKYMDSRTVGNTPRGL 105 Query: 240 SEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFM 416 +YF +Q+L+GL + H +LHRDLKP NLL+N LK+ DFGLAR + Sbjct: 106 ELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQLKLGDFGLARAFGIPVNTF 165 Query: 417 TEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELI 596 + VVT WYRAP++L+ S Y+ +ID+WS GCI E++ KPLFPG + QL+L+ +++ Sbjct: 166 SSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKLIFDIM 225 Query: 597 GTPNEA 614 GTPNE+ Sbjct: 226 GTPNES 231
>PCTK3_RAT (O35832) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 451 Score = 152 bits (385), Expect = 6e-37 Identities = 77/180 (42%), Positives = 111/180 (61%), Gaps = 2/180 (1%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQII-RSNQALSEEHC 254 +RE+ LL+ + H NIV + D+I + + + +E +D+DL Q + ++ + Sbjct: 165 IREVSLLKDLKHANIVTLHDLIHTDR-----SLTLVFEYLDSDLKQYLDHCGNLMNMHNV 219 Query: 255 QYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEYVV 431 + F++Q+LRGL Y H +LHRDLKP NLL+N +LK+ DFGLAR S T + VV Sbjct: 220 KIFMFQLLRGLAYCHRRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVV 279 Query: 432 TRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPNE 611 T WYR P++LL S+EY+ ID+W VGCI E+ KPLFPG +L L+ L+GTP E Sbjct: 280 TLWYRPPDVLLGSTEYSTPIDMWGVGCILYEMATGKPLFPGSTVKEELHLIFRLLGTPTE 339
>PCTK3_MOUSE (Q04899) Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 3) Length = 451 Score = 152 bits (385), Expect = 6e-37 Identities = 77/180 (42%), Positives = 111/180 (61%), Gaps = 2/180 (1%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQII-RSNQALSEEHC 254 +RE+ LL+ + H NIV + D+I + + + +E +D+DL Q + ++ + Sbjct: 165 IREVSLLKDLKHANIVTLHDLIHTDR-----SLTLVFEYLDSDLKQYLDHCGNLMNMHNV 219 Query: 255 QYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEYVV 431 + F++Q+LRGL Y H +LHRDLKP NLL+N +LK+ DFGLAR S T + VV Sbjct: 220 KIFMFQLLRGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVV 279 Query: 432 TRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPNE 611 T WYR P++LL S+EY+ ID+W VGCI E+ KPLFPG +L L+ L+GTP E Sbjct: 280 TLWYRPPDVLLGSTEYSTPIDMWGVGCILYEMATGKPLFPGSTVKEELHLIFRLLGTPTE 339
>CDC2H_THEPA (Q27032) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 298 Score = 152 bits (385), Expect = 6e-37 Identities = 78/179 (43%), Positives = 114/179 (63%), Gaps = 2/179 (1%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRS-NQALSEEHC 254 +REI LL+ + H NIV +RD+I + + +E +D DL +++ + + L Sbjct: 48 IREISLLKELHHPNIVWLRDVIHSEKCLT-----LVFEYLDQDLKKLLDACDGGLEPTTA 102 Query: 255 QYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEYVV 431 + FLYQILRG+ Y H +LHRDLKP NLL+N LK+ DFGLAR + T VV Sbjct: 103 KSFLYQILRGISYCHDHRILHRDLKPQNLLINREGVLKLADFGLARAFAIPVRSYTHEVV 162 Query: 432 TRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPN 608 T WYRAP++L+ S +Y+ A+D+WSVGCIF E+++ PLFPG QL+ + +++GTP+ Sbjct: 163 TLWYRAPDVLMGSKKYSTAVDIWSVGCIFAEMINGVPLFPGISEQDQLKRIFKILGTPS 221
>CDC2H_PLAYO (Q7RM49) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 289 Score = 152 bits (385), Expect = 6e-37 Identities = 80/188 (42%), Positives = 115/188 (61%), Gaps = 2/188 (1%) Frame = +3 Query: 51 DNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIR-S 227 D I + ++REI +L+ + H NIV + D+I +R + + +E +D DL ++I Sbjct: 40 DEGIPSTVSIREISILKELRHSNIVKLYDVIHAKKR-----LILVFEHLDQDLKKLIDVC 94 Query: 228 NQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-E 404 + L + FL Q+L G+ Y H VLHRDLKP NLL+N +LKI DFGLAR Sbjct: 95 DGGLESVTAKSFLLQLLNGIAYCHEHRVLHRDLKPQNLLINREGELKIADFGLARAFGIP 154 Query: 405 TDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLL 584 T VVT WYRAP++L+ S +Y+ ID+WSVGCIF E+++ +PLFPG QL + Sbjct: 155 ARRYTHEVVTLWYRAPDILMGSKKYSTPIDIWSVGCIFAEMVNGRPLFPGVSETDQLMRI 214 Query: 585 MELIGTPN 608 +++GTPN Sbjct: 215 FKILGTPN 222
>CDC2H_PLAFK (Q07785) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (PfPK5) Length = 288 Score = 152 bits (383), Expect = 1e-36 Identities = 80/189 (42%), Positives = 113/189 (59%), Gaps = 2/189 (1%) Frame = +3 Query: 75 TLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRSNQA-LSEEH 251 T+REI +L+ + H NIV + D+I +R + + +E +D DL +++ + L Sbjct: 47 TIREISILKELKHSNIVKLYDVIHTKKR-----LVLVFEHLDQDLKKLLDVCEGGLESVT 101 Query: 252 CQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEYV 428 + FL Q+L G+ Y H VLHRDLKP NLL+N +LKI DFGLAR T V Sbjct: 102 AKSFLLQLLNGIAYCHDRRVLHRDLKPQNLLINREGELKIADFGLARAFGIPVRKYTHEV 161 Query: 429 VTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPN 608 VT WYRAP++L+ S +Y+ ID+WSVGCIF E+++ PLFPG QL + ++GTPN Sbjct: 162 VTLWYRAPDVLMGSKKYSTTIDIWSVGCIFAEMVNGTPLFPGVSEADQLMRIFRILGTPN 221 Query: 609 EADLDFVNE 635 + V E Sbjct: 222 SKNWPNVTE 230
>CDC2H_PLAF7 (P61075) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 152 bits (383), Expect = 1e-36 Identities = 80/189 (42%), Positives = 113/189 (59%), Gaps = 2/189 (1%) Frame = +3 Query: 75 TLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRSNQA-LSEEH 251 T+REI +L+ + H NIV + D+I +R + + +E +D DL +++ + L Sbjct: 47 TIREISILKELKHSNIVKLYDVIHTKKR-----LVLVFEHLDQDLKKLLDVCEGGLESVT 101 Query: 252 CQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEYV 428 + FL Q+L G+ Y H VLHRDLKP NLL+N +LKI DFGLAR T V Sbjct: 102 AKSFLLQLLNGIAYCHDRRVLHRDLKPQNLLINREGELKIADFGLARAFGIPVRKYTHEV 161 Query: 429 VTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPN 608 VT WYRAP++L+ S +Y+ ID+WSVGCIF E+++ PLFPG QL + ++GTPN Sbjct: 162 VTLWYRAPDVLMGSKKYSTTIDIWSVGCIFAEMVNGTPLFPGVSEADQLMRIFRILGTPN 221 Query: 609 EADLDFVNE 635 + V E Sbjct: 222 SKNWPNVTE 230
>CDC2H_PLABA (Q4Z6R1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 151 bits (382), Expect = 1e-36 Identities = 78/179 (43%), Positives = 111/179 (62%), Gaps = 2/179 (1%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIR-SNQALSEEHC 254 +REI +L+ + H NIV + D+I +R + + +E +D DL ++I + L Sbjct: 48 IREISILKELRHSNIVKLYDVIHAKKR-----LILVFEHLDQDLKKLIDVCDGGLESVTA 102 Query: 255 QYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEYVV 431 + FL Q+L G+ Y H VLHRDLKP NLL+N +LKI DFGLAR T VV Sbjct: 103 KSFLLQLLNGIAYCHEHRVLHRDLKPQNLLINREGELKIADFGLARAFGIPARRYTHEVV 162 Query: 432 TRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPN 608 T WYRAP++L+ S +Y+ ID+WSVGCIF E+++ +PLFPG QL + +++GTPN Sbjct: 163 TLWYRAPDILMGSKKYSTPIDIWSVGCIFAEMVNGRPLFPGASETDQLMRIFKILGTPN 221
>CDK7_RAT (P51952) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 protein kinase) (P39 Mo15) (Fragment) Length = 329 Score = 151 bits (382), Expect = 1e-36 Identities = 81/196 (41%), Positives = 119/196 (60%), Gaps = 3/196 (1%) Frame = +3 Query: 33 KIANAFDNKIDAKRT-LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDL 209 K+ + + K RT LREIKLL+ + H NI+ + D +++ + ++ M+TDL Sbjct: 36 KLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHK-----SNISLVFDFMETDL 90 Query: 210 HQIIRSNQ-ALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGL 386 II+ N L+ H + ++ L+GL+Y+H +LHRDLKP+NLLL+ N LK+ DFGL Sbjct: 91 EVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGL 150 Query: 387 ARTTSETDFM-TEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDH 563 A++ ++ T VVTRWYRAPELL + Y +D+W+VGCI EL+ R P PG Sbjct: 151 AKSFGSPNWAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSD 210 Query: 564 VHQLRLLMELIGTPNE 611 + QL + E +GTP E Sbjct: 211 LDQLTRIFETLGTPTE 226
>CDK7_MOUSE (Q03147) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (Protein-tyrosine kinase MPK-7) (CR4 protein kinas Length = 346 Score = 150 bits (380), Expect = 2e-36 Identities = 82/196 (41%), Positives = 118/196 (60%), Gaps = 3/196 (1%) Frame = +3 Query: 33 KIANAFDNKIDAKRT-LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDL 209 K+ + + K RT LREIKLL+ + H NI+ + D +++ + ++ M+TDL Sbjct: 44 KLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHK-----SNISLVFDFMETDL 98 Query: 210 HQIIRSNQ-ALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGL 386 II+ N L+ H + ++ L+GL+Y+H +LHRDLKP+NLLL+ N LK+ DFGL Sbjct: 99 EVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGL 158 Query: 387 ARTT-SETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDH 563 A++ S T VVTRWYRAPELL + Y +D+W+VGCI EL+ R P PG Sbjct: 159 AKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSD 218 Query: 564 VHQLRLLMELIGTPNE 611 + QL + E +GTP E Sbjct: 219 LDQLTRIFETLGTPTE 234
>CDK7_HUMAN (P50613) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (STK1) (CAK1) Length = 346 Score = 150 bits (380), Expect = 2e-36 Identities = 82/196 (41%), Positives = 118/196 (60%), Gaps = 3/196 (1%) Frame = +3 Query: 33 KIANAFDNKIDAKRT-LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDL 209 K+ + + K RT LREIKLL+ + H NI+ + D +++ + ++ M+TDL Sbjct: 44 KLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHK-----SNISLVFDFMETDL 98 Query: 210 HQIIRSNQ-ALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGL 386 II+ N L+ H + ++ L+GL+Y+H +LHRDLKP+NLLL+ N LK+ DFGL Sbjct: 99 EVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGL 158 Query: 387 ARTT-SETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDH 563 A++ S T VVTRWYRAPELL + Y +D+W+VGCI EL+ R P PG Sbjct: 159 AKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSD 218 Query: 564 VHQLRLLMELIGTPNE 611 + QL + E +GTP E Sbjct: 219 LDQLTRIFETLGTPTE 234
>CDKL2_RAT (Q5XIT0) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| Length = 507 Score = 150 bits (380), Expect = 2e-36 Identities = 76/204 (37%), Positives = 125/204 (61%), Gaps = 4/204 (1%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMD-TDL 209 K + D+K+ K +REIKLL+ + HEN+V + ++ +R Y+ +E +D T L Sbjct: 34 KFLESDDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKKKKRW-----YLVFEFVDHTIL 88 Query: 210 HQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLA 389 + L + Q +L+QI+ G+ + HS N++HRD+KP N+L++ + +K+CDFG A Sbjct: 89 DDLKLFPNGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENILVSQSGVVKLCDFGFA 148 Query: 390 RTTSET-DFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHV 566 RT + + T+YV TRWYRAPELL+ +Y A+D+W++GC+ +E++ +PLFPG + Sbjct: 149 RTLAAPGEVYTDYVATRWYRAPELLVGDVKYGKAVDIWAIGCLVIEMLMGQPLFPGESDI 208 Query: 567 HQLRLLMELIGT--PNEADLDFVN 632 QL +M +G P +L + N Sbjct: 209 DQLHHIMTCLGNLIPRHQELFYKN 232
>ICK_RAT (Q62726) Serine/threonine-protein kinase ICK (EC 2.7.11.22)| (Intestinal cell kinase) (MAK-related kinase) (MRK) Length = 629 Score = 150 bits (380), Expect = 2e-36 Identities = 78/182 (42%), Positives = 113/182 (62%), Gaps = 2/182 (1%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFND-VYIAYELMDTDLHQIIRS-NQALSEEH 251 LRE+K L+ ++H NIV ++++I ND +Y +E M +L+Q+I+ N+ E Sbjct: 48 LREVKSLKKLNHANIVKLKEVIRE------NDHLYFIFEYMKENLYQLIKERNKLFPESA 101 Query: 252 CQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTSETDFMTEYVV 431 + +YQIL+GL +IH HRDLKP NLL +KI DFGLAR T+YV Sbjct: 102 IRNIMYQILQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSRPPYTDYVS 161 Query: 432 TRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPNE 611 TRWYRAPE+LL S+ Y++ IDVW+VGCI E+ +PLFPG + + + +++GTP + Sbjct: 162 TRWYRAPEVLLRSTNYSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKK 221 Query: 612 AD 617 D Sbjct: 222 TD 223
>PCTK1_RAT (Q63686) Serine/threonine-protein kinase PCTAIRE-1 (EC 2.7.11.22)| (PCTAIRE-motif protein kinase 1) Length = 496 Score = 150 bits (380), Expect = 2e-36 Identities = 77/180 (42%), Positives = 109/180 (60%), Gaps = 2/180 (1%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRS-NQALSEEHC 254 +RE+ LL+ + H NIV + DII + + + +E +D DL Q + ++ + Sbjct: 209 IREVSLLKDLKHANIVTLHDIIHTEK-----SLTLVFEYLDKDLKQYLDDCGNVINMHNV 263 Query: 255 QYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEYVV 431 + FL+Q+LRGL Y H VLHRDLKP NLL+N +LK+ DFGLA S T + VV Sbjct: 264 KLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLAYAKSIPTKTYSNEVV 323 Query: 432 TRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPNE 611 T WYR P++LL S++Y+ ID+W VGCIF E+ +PLFPG QL + ++GTP E Sbjct: 324 TLWYRPPDILLGSTDYSGQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTE 383
>CDC28_YEAST (P00546) Cell division control protein 28 (EC 2.7.11.22)| Length = 298 Score = 150 bits (380), Expect = 2e-36 Identities = 75/183 (40%), Positives = 114/183 (62%), Gaps = 4/183 (2%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQI---IRSNQALSEE 248 +REI LL+ + +NIV + DI+ + + +Y+ +E +D DL + I +Q L + Sbjct: 56 IREISLLKELKDDNIVRLYDIV----HSDAHKLYLVFEFLDLDLKRYMEGIPKDQPLGAD 111 Query: 249 HCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEY 425 + F+ Q+ +G+ Y HS +LHRDLKP NLL+N + +LK+ DFGLAR T Sbjct: 112 IVKKFMMQLCKGIAYCHSHRILHRDLKPQNLLINKDGNLKLGDFGLARAFGVPLRAYTHE 171 Query: 426 VVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTP 605 +VT WYRAPE+LL +Y+ +D WS+GCIF E+ +RKP+F G + Q+ + ++GTP Sbjct: 172 IVTLWYRAPEVLLGGKQYSTGVDTWSIGCIFAEMCNRKPIFSGDSEIDQIFKIFRVLGTP 231 Query: 606 NEA 614 NEA Sbjct: 232 NEA 234
>CDKL2_MOUSE (Q9QUK0) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIAMRE) Length = 568 Score = 150 bits (380), Expect = 2e-36 Identities = 76/204 (37%), Positives = 125/204 (61%), Gaps = 4/204 (1%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMD-TDL 209 K + D+K+ K +REIKLL+ + HEN+V + ++ +R Y+ +E +D T L Sbjct: 34 KFLESDDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKKKKRW-----YLVFEFVDHTIL 88 Query: 210 HQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLA 389 + L + Q +L+QI+ G+ + HS N++HRD+KP N+L++ + +K+CDFG A Sbjct: 89 DDLKLFPNGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENILVSQSGVVKLCDFGFA 148 Query: 390 RTTSET-DFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHV 566 RT + + T+YV TRWYRAPELL+ +Y A+D+W++GC+ +E++ +PLFPG + Sbjct: 149 RTLAAPGEVYTDYVATRWYRAPELLVGDVKYGKAVDIWAIGCLVIEMLMGQPLFPGESDI 208 Query: 567 HQLRLLMELIGT--PNEADLDFVN 632 QL +M +G P +L + N Sbjct: 209 DQLHHIMTCLGNLIPRHQELFYKN 232
>ICK_HUMAN (Q9UPZ9) Serine/threonine-protein kinase ICK (EC 2.7.11.22)| (Intestinal cell kinase) (hICK) (MAK-related kinase) (MRK) (Laryngeal cancer kinase 2) (LCK2) Length = 632 Score = 150 bits (379), Expect = 3e-36 Identities = 77/182 (42%), Positives = 113/182 (62%), Gaps = 2/182 (1%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFND-VYIAYELMDTDLHQIIRS-NQALSEEH 251 LRE+K L+ ++H N+V ++++I ND +Y +E M +L+Q+I+ N+ E Sbjct: 48 LREVKSLKKLNHANVVKLKEVIRE------NDHLYFIFEYMKENLYQLIKERNKLFPESA 101 Query: 252 CQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTSETDFMTEYVV 431 + +YQIL+GL +IH HRDLKP NLL +KI DFGLAR T+YV Sbjct: 102 IRNIMYQILQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVS 161 Query: 432 TRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPNE 611 TRWYRAPE+LL S+ Y++ IDVW+VGCI E+ +PLFPG + + + +++GTP + Sbjct: 162 TRWYRAPEVLLRSTNYSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKK 221 Query: 612 AD 617 D Sbjct: 222 TD 223
>CDC2H_PLACH (Q4Y4B1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) Length = 288 Score = 150 bits (379), Expect = 3e-36 Identities = 78/179 (43%), Positives = 111/179 (62%), Gaps = 2/179 (1%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIR-SNQALSEEHC 254 +REI +L+ + H NIV + D+I +R + + +E +D DL ++I + L Sbjct: 48 IREISILKELRHSNIVKLYDVIHAKKR-----LILVFEHLDQDLKKLIDVCDGGLESVTA 102 Query: 255 QYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEYVV 431 + FL Q+L G+ Y H VLHRDLKP NLL+N +LKI DFGLAR T VV Sbjct: 103 KSFLLQLLNGIAYCHEHRVLHRDLKPQNLLINREGELKIADFGLARAFGIPARRYTHEVV 162 Query: 432 TRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPN 608 T WYRAP++L+ S +Y+ ID+WSVGCIF E+++ +PLFPG QL + +++GTPN Sbjct: 163 TLWYRAPDILMGSKKYSTPIDIWSVGCIFAEMVNGRPLFPGVSDTDQLMRIFKILGTPN 221
>ICK_MOUSE (Q9JKV2) Serine/threonine-protein kinase ICK (EC 2.7.11.22)| (Intestinal cell kinase) (mICK) (MAK-related kinase) (MRK) Length = 629 Score = 150 bits (379), Expect = 3e-36 Identities = 77/182 (42%), Positives = 113/182 (62%), Gaps = 2/182 (1%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFND-VYIAYELMDTDLHQIIRS-NQALSEEH 251 LRE+K L+ ++H NIV ++++I ND +Y +E M +L+Q+I+ N+ E Sbjct: 48 LREVKSLKKLNHANIVKLKEVIRE------NDHLYFIFEYMKENLYQLIKERNKLFPESA 101 Query: 252 CQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTSETDFMTEYVV 431 + +YQIL+GL +IH HRDLKP NLL +KI DFGLAR T+YV Sbjct: 102 IRNIMYQILQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSRPPYTDYVS 161 Query: 432 TRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPNE 611 TRWYRAPE+LL S+ Y++ ID+W+VGCI E+ +PLFPG + + + +++GTP + Sbjct: 162 TRWYRAPEVLLRSTNYSSPIDIWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKK 221 Query: 612 AD 617 D Sbjct: 222 TD 223
>CDK2_MESAU (P48963) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 150 bits (378), Expect = 4e-36 Identities = 77/181 (42%), Positives = 113/181 (62%), Gaps = 3/181 (1%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRSNQA--LSEEH 251 +REI LL+ ++H NIV + D+I N +Y+ +EL+ DL + + ++ + Sbjct: 49 IREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFELLHQDLKKFMDASAVTGIPLPL 103 Query: 252 CQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEYV 428 + +L+Q+L+GL + HS VLHRDLKP NLL+NA +K+ DFGLAR T V Sbjct: 104 IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINAEGSIKLADFGLARAFGVPVRTYTHEV 163 Query: 429 VTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPN 608 VT WYRAPE+LL Y+ A+D+WS+GCIF E++ R+ LFPG + QL + +GTP+ Sbjct: 164 VTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPD 223 Query: 609 E 611 E Sbjct: 224 E 224
>CDC2H_PLAVI (Q9XZD6) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (Pvcrk2) Length = 288 Score = 150 bits (378), Expect = 4e-36 Identities = 79/188 (42%), Positives = 113/188 (60%), Gaps = 2/188 (1%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIR-SNQALSEEHC 254 +REI +L+ + H NIV + D+I +R + + +E +D DL +++ + L Sbjct: 48 IREISILKELKHSNIVKLYDVIHTKKR-----LILVFEHLDQDLKKLLDVCDGGLESVTA 102 Query: 255 QYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEYVV 431 + FL Q+L G+ Y H VLHRDLKP NLL+N +LKI DFGLAR T VV Sbjct: 103 KSFLLQLLSGIAYCHEHRVLHRDLKPQNLLINREGELKIADFGLARAFGIPVRKYTHEVV 162 Query: 432 TRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPNE 611 T WYRAP++L+ S +Y+ ID+WSVGCIF E+++ +PLFPG QL + ++GTPN Sbjct: 163 TLWYRAPDILMGSKKYSTPIDMWSVGCIFAEMVNGRPLFPGVSETDQLMRIFRILGTPNS 222 Query: 612 ADLDFVNE 635 + V E Sbjct: 223 ENWPNVTE 230
>CDK2_XENLA (P23437) Cell division protein kinase 2 (EC 2.7.11.22) (CDC2| homolog Eg1 protein kinase) Length = 297 Score = 149 bits (377), Expect = 5e-36 Identities = 76/181 (41%), Positives = 114/181 (62%), Gaps = 3/181 (1%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRSNQ--ALSEEH 251 +REI LL+ ++H NIV + D+I N +Y+ +E ++ DL + + + +S Sbjct: 49 IREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLNQDLKKFMDGSNISGISLAL 103 Query: 252 CQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEYV 428 + +L+Q+L+GL + HS VLHRDLKP NLL+N++ +K+ DFGLAR T V Sbjct: 104 VKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINSDGAIKLADFGLARAFGVPVRTFTHEV 163 Query: 429 VTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPN 608 VT WYRAPE+LL Y+ A+D+WS+GCIF E++ R+ LFPG + QL + +GTP+ Sbjct: 164 VTLWYRAPEILLGCKFYSTAVDIWSLGCIFAEMITRRALFPGDSEIDQLFRIFRTLGTPD 223 Query: 609 E 611 E Sbjct: 224 E 224
>CDK2_RAT (Q63699) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 149 bits (376), Expect = 7e-36 Identities = 77/181 (42%), Positives = 112/181 (61%), Gaps = 3/181 (1%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRSNQ--ALSEEH 251 +REI LL+ ++H NIV + D+I N +Y+ +E + DL + + ++ L Sbjct: 49 IREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLHQDLKKFMDASALTGLPLPL 103 Query: 252 CQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEYV 428 + +L+Q+L+GL + HS VLHRDLKP NLL+NA +K+ DFGLAR T V Sbjct: 104 IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINAEGSIKLADFGLARAFGVPVRTYTHEV 163 Query: 429 VTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPN 608 VT WYRAPE+LL Y+ A+D+WS+GCIF E++ R+ LFPG + QL + +GTP+ Sbjct: 164 VTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPD 223 Query: 609 E 611 E Sbjct: 224 E 224
>CDK5_XENLA (P51166) Cell division protein kinase 5 (EC 2.7.11.22) (Neuronal| cyclin-dependent kinase 5) Length = 292 Score = 149 bits (376), Expect = 7e-36 Identities = 81/181 (44%), Positives = 112/181 (61%), Gaps = 3/181 (1%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRS-NQALSEEHC 254 LREI LL+ + H+NIV + D++ ++ + +E D DL + S N L E Sbjct: 49 LREICLLKELKHKNIVRLHDVLHSDKKLT-----LVFEFCDQDLKKYFDSCNGDLDPEIV 103 Query: 255 QYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEYVV 431 + F+YQ+L+GL + HS NVLHRDLKP NLL+N N +LK+ DFGLAR + VV Sbjct: 104 KSFMYQLLKGLAFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVV 163 Query: 432 TRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDR-KPLFPGRDHVHQLRLLMELIGTPN 608 T WYR P++L + Y+ +ID+WS GCIF EL + +PLFPG D QL+ + L+GTP Sbjct: 164 TLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPT 223 Query: 609 E 611 E Sbjct: 224 E 224
>CCRK_HUMAN (Q8IZL9) Cell cycle-related kinase (EC 2.7.11.22)| (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) Length = 346 Score = 149 bits (376), Expect = 7e-36 Identities = 76/183 (41%), Positives = 119/183 (65%), Gaps = 4/183 (2%) Frame = +3 Query: 72 RTLREIKLLRHM-DHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRSNQA-LSE 245 + LREIK L+ M D++ +V ++ + P +A+E M +DL +++R Q L++ Sbjct: 47 QALREIKALQEMEDNQYVVQLKAVFPHG-----GGFVLAFEFMLSDLAEVVRHAQRPLAQ 101 Query: 246 EHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTSE--TDFMT 419 + +L +L+G+ + H+ N++HRDLKP+NLL++A+ LKI DFGLAR S + T Sbjct: 102 AQVKSYLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYT 161 Query: 420 EYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIG 599 V TRWYRAPELL + +Y +D+WSVGCI EL++ PLFPG++ + QL ++ ++G Sbjct: 162 HQVATRWYRAPELLYGARQYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILG 221 Query: 600 TPN 608 TPN Sbjct: 222 TPN 224
>CDK5_BOVIN (Q02399) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Proline-directed protein kinase 33 kDa subunit) (PDPK) Length = 292 Score = 149 bits (375), Expect = 9e-36 Identities = 81/181 (44%), Positives = 113/181 (62%), Gaps = 3/181 (1%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRS-NQALSEEHC 254 LREI LL+ + H+NIV + D++ ++ + +E D DL + S N L E Sbjct: 49 LREICLLKELKHKNIVRLHDVLHSDKKLT-----LVFEFCDQDLKKYFDSCNGDLDPEIV 103 Query: 255 QYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEYVV 431 + FL+Q+L+GL + HS NVLHRDLKP NLL+N N +LK+ DFGLAR + VV Sbjct: 104 KSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVV 163 Query: 432 TRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDR-KPLFPGRDHVHQLRLLMELIGTPN 608 T WYR+P++L + Y+ +ID+WS GCIF EL + +PLFPG D QL+ + L+GTP Sbjct: 164 TLWYRSPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPT 223 Query: 609 E 611 E Sbjct: 224 E 224
>CDK2_BOVIN (Q5E9Y0) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 149 bits (375), Expect = 9e-36 Identities = 76/181 (41%), Positives = 113/181 (62%), Gaps = 3/181 (1%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRSNQ--ALSEEH 251 +REI LL+ ++H NIV + D+I N +Y+ +E + DL + + ++ + Sbjct: 49 IREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLHQDLKKFMDASALTGIPLPL 103 Query: 252 CQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEYV 428 + +L+Q+L+GL + HS VLHRDLKP NLL+NA+ +K+ DFGLAR T V Sbjct: 104 IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINADGSIKLADFGLARAFGVPVRTYTHEV 163 Query: 429 VTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPN 608 VT WYRAPE+LL Y+ A+D+WS+GCIF E++ R+ LFPG + QL + +GTP+ Sbjct: 164 VTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPD 223 Query: 609 E 611 E Sbjct: 224 E 224
>CCRK_PONPY (Q5R7I7) Cell cycle-related kinase (EC 2.7.11.22)| Length = 346 Score = 148 bits (374), Expect = 1e-35 Identities = 75/183 (40%), Positives = 120/183 (65%), Gaps = 4/183 (2%) Frame = +3 Query: 72 RTLREIKLLRHM-DHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRSNQA-LSE 245 + LREIK L+ M D++ +V ++ + P + +A+E M +DL +++R Q L++ Sbjct: 47 QALREIKALQEMEDNQYVVQLKAVFPHSA-----GFVLAFEFMLSDLAEVVRHAQRPLAQ 101 Query: 246 EHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTSE--TDFMT 419 + +L +L+G+ + H+ N++HRDLKP+NLL++A+ LKI DFGLAR S + T Sbjct: 102 AQVKSYLQMLLKGVSFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYT 161 Query: 420 EYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIG 599 V TRWYRAPELL + +Y +D+W+VGCI EL++ PLFPG++ + QL ++ ++G Sbjct: 162 HQVATRWYRAPELLYGARQYDQGVDLWAVGCIMGELLNGSPLFPGKNDIEQLCYVLRILG 221 Query: 600 TPN 608 TPN Sbjct: 222 TPN 224
>CDK3_HUMAN (Q00526) Cell division protein kinase 3 (EC 2.7.11.22)| Length = 305 Score = 148 bits (374), Expect = 1e-35 Identities = 76/181 (41%), Positives = 112/181 (61%), Gaps = 3/181 (1%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRSNQA--LSEEH 251 +REI LL+ + H NIV + D++ ++ +Y+ +E + DL + + S L Sbjct: 49 IREISLLKELKHPNIVRLLDVVHNERK-----LYLVFEFLSQDLKKYMDSTPGSELPLHL 103 Query: 252 CQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEYV 428 + +L+Q+L+G+ + HS V+HRDLKP NLL+N +K+ DFGLAR T V Sbjct: 104 IKSYLFQLLQGVSFCHSHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEV 163 Query: 429 VTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPN 608 VT WYRAPE+LL S YT A+D+WS+GCIF E++ RK LFPG + QL + ++GTP+ Sbjct: 164 VTLWYRAPEILLGSKFYTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPS 223 Query: 609 E 611 E Sbjct: 224 E 224
>CDK2_CRIGR (O55076) Cell division protein kinase 2 (EC 2.7.11.22)| Length = 298 Score = 148 bits (374), Expect = 1e-35 Identities = 76/181 (41%), Positives = 112/181 (61%), Gaps = 3/181 (1%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRSNQA--LSEEH 251 +REI LL+ ++H NIV + D+I N +Y+ +E + DL + + ++ + Sbjct: 49 IREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLHQDLKKFMDASAVTGIPLPL 103 Query: 252 CQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEYV 428 + +L+Q+L+GL + HS VLHRDLKP NLL+NA +K+ DFGLAR T V Sbjct: 104 IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINAEGSIKLADFGLARAFGVPVRTYTHEV 163 Query: 429 VTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPN 608 VT WYRAPE+LL Y+ A+D+WS+GCIF E++ R+ LFPG + QL + +GTP+ Sbjct: 164 VTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPD 223 Query: 609 E 611 E Sbjct: 224 E 224
>CDK5_MOUSE (P49615) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) (CRK6) Length = 292 Score = 148 bits (373), Expect = 2e-35 Identities = 81/181 (44%), Positives = 112/181 (61%), Gaps = 3/181 (1%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRS-NQALSEEHC 254 LREI LL+ + H+NIV + D++ ++ + +E D DL + S N L E Sbjct: 49 LREICLLKELKHKNIVRLHDVLHSDKKLT-----LVFEFCDQDLKKYFDSCNGDLDPEIV 103 Query: 255 QYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEYVV 431 + FL+Q+L+GL + HS NVLHRDLKP NLL+N N +LK+ DFGLAR + VV Sbjct: 104 KSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVV 163 Query: 432 TRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDR-KPLFPGRDHVHQLRLLMELIGTPN 608 T WYR P++L + Y+ +ID+WS GCIF EL + +PLFPG D QL+ + L+GTP Sbjct: 164 TLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPT 223 Query: 609 E 611 E Sbjct: 224 E 224
>CDK5_HUMAN (Q00535) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) Length = 292 Score = 148 bits (373), Expect = 2e-35 Identities = 81/181 (44%), Positives = 112/181 (61%), Gaps = 3/181 (1%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRS-NQALSEEHC 254 LREI LL+ + H+NIV + D++ ++ + +E D DL + S N L E Sbjct: 49 LREICLLKELKHKNIVRLHDVLHSDKKLT-----LVFEFCDQDLKKYFDSCNGDLDPEIV 103 Query: 255 QYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEYVV 431 + FL+Q+L+GL + HS NVLHRDLKP NLL+N N +LK+ DFGLAR + VV Sbjct: 104 KSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVV 163 Query: 432 TRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDR-KPLFPGRDHVHQLRLLMELIGTPN 608 T WYR P++L + Y+ +ID+WS GCIF EL + +PLFPG D QL+ + L+GTP Sbjct: 164 TLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPT 223 Query: 609 E 611 E Sbjct: 224 E 224
>CDK5_DROME (P48609) Cell division protein kinase 5 homolog (EC 2.7.11.22)| Length = 294 Score = 148 bits (373), Expect = 2e-35 Identities = 81/181 (44%), Positives = 111/181 (61%), Gaps = 3/181 (1%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRS-NQALSEEHC 254 LREI LL+ + H+NIV + D++ ++ + +E D DL + S N + C Sbjct: 49 LREICLLKELKHKNIVRLIDVLHSDKKLT-----LVFEHCDQDLKKYFDSLNGEIDMAVC 103 Query: 255 QYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEYVV 431 + F+ Q+LRGL + HS NVLHRDLKP NLL+N N +LK+ DFGLAR + VV Sbjct: 104 RSFMLQLLRGLAFCHSHNVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVKCYSAEVV 163 Query: 432 TRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDR-KPLFPGRDHVHQLRLLMELIGTPN 608 T WYR P++L + YT +ID+WS GCI EL D +PLFPG D + QL + ++GTPN Sbjct: 164 TLWYRPPDVLFGAKLYTTSIDMWSAGCILAELADAGRPLFPGSDVLDQLMKIFRVLGTPN 223 Query: 609 E 611 E Sbjct: 224 E 224
>CDK6_MOUSE (Q64261) Cell division protein kinase 6 (EC 2.7.11.22)| (Serine/threonine-protein kinase PLSTIRE) (CRK2) Length = 326 Score = 148 bits (373), Expect = 2e-35 Identities = 77/186 (41%), Positives = 115/186 (61%), Gaps = 5/186 (2%) Frame = +3 Query: 75 TLREIKLLRHMD---HENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRS--NQAL 239 T+RE+ +LRH++ H N+V + D+ ++ + + +E +D DL + + Sbjct: 58 TIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGV 117 Query: 240 SEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTSETDFMT 419 E + ++Q+LRGL ++HS V+HRDLKP N+L+ ++ +K+ DFGLAR S +T Sbjct: 118 PTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALT 177 Query: 420 EYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIG 599 VVT WYRAPE+LL SS Y +D+WSVGCIF E+ RKPLF G V QL ++++IG Sbjct: 178 SVVVTLWYRAPEVLLQSS-YATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDIIG 236 Query: 600 TPNEAD 617 P E D Sbjct: 237 LPGEED 242
>MAK_MOUSE (Q04859) Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male| germ cell-associated kinase) (Protein kinase RCK) Length = 622 Score = 147 bits (372), Expect = 2e-35 Identities = 77/187 (41%), Positives = 115/187 (61%), Gaps = 2/187 (1%) Frame = +3 Query: 63 DAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFND-VYIAYELMDTDLHQIIRS-NQA 236 D LRE+K L+ ++H N++ ++++I ND +Y +E M +L+Q+++ N+ Sbjct: 43 DECMNLREVKSLKKLNHANVIKLKEVIRE------NDHLYFVFEYMKENLYQLMKDRNKL 96 Query: 237 LSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTSETDFM 416 E + +YQIL+GL +IH HRD+KP NLL +KI DFGLAR Sbjct: 97 FPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPY 156 Query: 417 TEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELI 596 T+YV TRWYRAPE+LL SS Y++ IDVW+VG I EL +PLFPG V ++ + +++ Sbjct: 157 TDYVSTRWYRAPEVLLRSSVYSSPIDVWAVGSIMAELYTFRPLFPGTSEVDEIFKICQVL 216 Query: 597 GTPNEAD 617 GTP ++D Sbjct: 217 GTPKKSD 223
>CDKL2_MACFA (Q4R7T5) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| Length = 570 Score = 147 bits (372), Expect = 2e-35 Identities = 77/204 (37%), Positives = 123/204 (60%), Gaps = 4/204 (1%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMD-TDL 209 K + D+K+ K +REIKLL+ + HEN+V + ++ +R Y+ +E +D T L Sbjct: 34 KFLESDDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKKKKRW-----YLVFEFVDHTIL 88 Query: 210 HQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLA 389 + L + Q +L+QI+ G+ + HS N++HRD+KP N+L++ + +K+CDFG A Sbjct: 89 DDLELFPNGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENILVSQSGVVKLCDFGFA 148 Query: 390 RTTSET-DFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHV 566 RT + + T+YV TRWYRAPELL+ +Y A+DVW++GC+ E+ +PLFPG + Sbjct: 149 RTLAAPGEVYTDYVATRWYRAPELLVGDVKYGKAVDVWAIGCLVTEMFMGEPLFPGDSDI 208 Query: 567 HQLRLLMELIGT--PNEADLDFVN 632 QL +M +G P +L + N Sbjct: 209 DQLYHIMMCLGNLIPRHQELFYKN 232
>CDKL4_MOUSE (Q3TZA2) Cyclin-dependent kinase-like 4 (EC 2.7.11.22)| Length = 342 Score = 147 bits (372), Expect = 2e-35 Identities = 71/190 (37%), Positives = 120/190 (63%), Gaps = 1/190 (0%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMD-TDL 209 K + D+++ K LREI++L+ + H N+V + ++ ++ +++ +E D T L Sbjct: 34 KFVESEDDRVVRKIALREIRMLKQLKHPNLVNLIEVFRRKRK-----MHLVFEYCDHTLL 88 Query: 210 HQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLA 389 +++ R+ +S+ + L+Q L+ L + H N +HRD+KP N+L+ +KICDFG A Sbjct: 89 NELERNPNGVSDGVIKSVLWQTLQALNFCHKHNCIHRDVKPENILITKQGMIKICDFGFA 148 Query: 390 RTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVH 569 R D T+YV TRWYRAPELL+ ++Y +++DVW+VGC+F EL+ +PL+PG+ V Sbjct: 149 RILIPGDAYTDYVATRWYRAPELLVGDTKYGSSVDVWAVGCVFAELLTGQPLWPGKSDVD 208 Query: 570 QLRLLMELIG 599 QL L++ +G Sbjct: 209 QLYLIIRTLG 218
>CRK1_SCHPO (Q12126) Serine/threonine-protein kinase crk1 (EC 2.7.11.23)| (Mitotic catastrophe suppressor 6) Length = 335 Score = 147 bits (372), Expect = 2e-35 Identities = 75/187 (40%), Positives = 113/187 (60%), Gaps = 1/187 (0%) Frame = +3 Query: 48 FDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRS 227 F + ID LREIK LR H+N++ + D+ + +++ I E +D+DL +I+ Sbjct: 47 FKDGIDIS-ALREIKFLRESRHDNVIELVDVF-----STKSNLNIILEFLDSDLEMLIKD 100 Query: 228 NQALSEE-HCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTSE 404 + + H + ++ +LRGL +IHS +LHRDLKP+NLL++++ LK+ DFGL+R Sbjct: 101 KFIVFQPAHIKSWMVMLLRGLHHIHSRFILHRDLKPNNLLISSDGVLKLADFGLSRDFGT 160 Query: 405 TDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLL 584 M+ V+TRWYR PEL + Y +D+WSVGCIF ELM R P PG + QL ++ Sbjct: 161 PSHMSHQVITRWYRPPELFMGCRSYGTGVDMWSVGCIFAELMLRTPYLPGESDLDQLNVI 220 Query: 585 MELIGTP 605 +GTP Sbjct: 221 FRALGTP 227
>MHK_ARATH (P43294) Serine/threonine-protein kinase MHK (EC 2.7.11.22)| Length = 443 Score = 147 bits (372), Expect = 2e-35 Identities = 77/178 (43%), Positives = 112/178 (62%), Gaps = 1/178 (0%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRSNQA-LSEEHC 254 LRE+K LR ++H +I+ +++I+ N+++ +E MD +L+ I++ + SE Sbjct: 56 LREVKALRKLNHPHIIKLKEIV-----REHNELFFIFECMDHNLYHIMKERERPFSEGEI 110 Query: 255 QYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTSETDFMTEYVVT 434 + F+ Q+L+GL ++H HRDLKP NLL+ N LKI DFGLAR + TEYV T Sbjct: 111 RSFMSQMLQGLAHMHKNGYFHRDLKPENLLVTNNI-LKIADFGLAREVASMPPYTEYVST 169 Query: 435 RWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPN 608 RWYRAPE+LL SS YT A+D+W+VG I EL PLFPG + QL + ++G P+ Sbjct: 170 RWYRAPEVLLQSSLYTPAVDMWAVGAILAELYALTPLFPGESEIDQLYKICCVLGKPD 227
>CDKL2_PONPY (Q5R754) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| Length = 493 Score = 147 bits (372), Expect = 2e-35 Identities = 77/204 (37%), Positives = 123/204 (60%), Gaps = 4/204 (1%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMD-TDL 209 K + D+K+ K +REIKLL+ + HEN+V + ++ +R Y+ +E +D T L Sbjct: 34 KFLESDDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKKKKRW-----YLVFEFVDHTIL 88 Query: 210 HQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLA 389 + L + Q +L+QI+ G+ + HS N++HRD+KP N+L++ + +K+CDFG A Sbjct: 89 DDLELFPNGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENILVSKSGVVKLCDFGFA 148 Query: 390 RTTSET-DFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHV 566 RT + + T+YV TRWYRAPELL+ +Y A+DVW++GC+ E+ +PLFPG + Sbjct: 149 RTLAAPGEVYTDYVATRWYRAPELLVGDVKYGKAVDVWAIGCLVTEMFMGEPLFPGDSDI 208 Query: 567 HQLRLLMELIGT--PNEADLDFVN 632 QL +M +G P +L + N Sbjct: 209 DQLYHIMMCLGNLIPRHQELFYKN 232
>CDKL2_HUMAN (Q92772) Cyclin-dependent kinase-like 2 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIAMRE) (Protein kinase p56 KKIAMRE) Length = 493 Score = 147 bits (372), Expect = 2e-35 Identities = 76/204 (37%), Positives = 122/204 (59%), Gaps = 2/204 (0%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMD-TDL 209 K + D+K+ K +REIKLL+ + HEN+V + ++ +R Y+ +E +D T L Sbjct: 34 KFLESDDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKKKKRW-----YLVFEFVDHTIL 88 Query: 210 HQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLA 389 + L + Q +L+QI+ G+ + HS N++HRD+KP N+L++ + +K+CDFG A Sbjct: 89 DDLELFPNGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENILVSQSGVVKLCDFGFA 148 Query: 390 RTTSET-DFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHV 566 RT + + T+YV TRWYRAPELL+ +Y A+DVW++GC+ E+ +PLFPG + Sbjct: 149 RTLAAPGEVYTDYVATRWYRAPELLVGDVKYGKAVDVWAIGCLVTEMFMGEPLFPGDSDI 208 Query: 567 HQLRLLMELIGTPNEADLDFVNEN 638 QL +M +G + N+N Sbjct: 209 DQLYHIMMCLGNLIPRHQELFNKN 232
>CDK6_HUMAN (Q00534) Cell division protein kinase 6 (EC 2.7.11.22)| (Serine/threonine-protein kinase PLSTIRE) Length = 326 Score = 147 bits (372), Expect = 2e-35 Identities = 77/186 (41%), Positives = 115/186 (61%), Gaps = 5/186 (2%) Frame = +3 Query: 75 TLREIKLLRHMD---HENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRS--NQAL 239 T+RE+ +LRH++ H N+V + D+ ++ + + +E +D DL + + Sbjct: 58 TIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGV 117 Query: 240 SEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTSETDFMT 419 E + ++Q+LRGL ++HS V+HRDLKP N+L+ ++ +K+ DFGLAR S +T Sbjct: 118 PTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALT 177 Query: 420 EYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIG 599 VVT WYRAPE+LL SS Y +D+WSVGCIF E+ RKPLF G V QL ++++IG Sbjct: 178 SVVVTLWYRAPEVLLQSS-YATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIG 236 Query: 600 TPNEAD 617 P E D Sbjct: 237 LPGEED 242
>CDK7_DICDI (P54685) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (MO15 homolog) Length = 362 Score = 147 bits (371), Expect = 3e-35 Identities = 80/196 (40%), Positives = 118/196 (60%), Gaps = 2/196 (1%) Frame = +3 Query: 36 IANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQ 215 I N D+ I+ +REIK+L+ + H+N+V + DI ++VY+ +ELM DL + Sbjct: 40 IQNQTDDGINFS-AIREIKILQELKHDNVVNLLDIFAHK-----SNVYLVFELMQWDLQE 93 Query: 216 IIRSNQA-LSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLAR 392 +I L + ++ +L+G++ H VLHRDLKP+NLL++ N DLK+ DFGLAR Sbjct: 94 VIEDKSIILKPADIKSYMKMLLQGIEACHRNWVLHRDLKPNNLLMSINGDLKLADFGLAR 153 Query: 393 TT-SETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVH 569 S + VT +YRAPELL + Y ++D+WS+GCIF ELM R P PG + Sbjct: 154 QYGSPNKVFSPQAVTIFYRAPELLFGAKSYGPSVDIWSIGCIFAELMLRTPYLPGTGEID 213 Query: 570 QLRLLMELIGTPNEAD 617 QLR + +GTPNE++ Sbjct: 214 QLRKICSALGTPNESN 229
>MAK_RAT (P20793) Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male| germ cell-associated kinase) Length = 622 Score = 147 bits (371), Expect = 3e-35 Identities = 77/187 (41%), Positives = 115/187 (61%), Gaps = 2/187 (1%) Frame = +3 Query: 63 DAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFND-VYIAYELMDTDLHQIIRS-NQA 236 D LRE+K L+ ++H N++ ++++I ND +Y +E M +L+Q+++ N+ Sbjct: 43 DECMNLREVKSLKKLNHANVIKLKEVIRE------NDHLYFIFEYMKENLYQLMKDRNKL 96 Query: 237 LSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTSETDFM 416 E + +YQIL+GL +IH HRD+KP NLL +KI DFGLAR Sbjct: 97 FPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPY 156 Query: 417 TEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELI 596 T+YV TRWYRAPE+LL SS Y++ IDVW+VG I EL +PLFPG V ++ + +++ Sbjct: 157 TDYVSTRWYRAPEVLLRSSVYSSPIDVWAVGSIMAELYTFRPLFPGTSEVDEIFKICQVL 216 Query: 597 GTPNEAD 617 GTP ++D Sbjct: 217 GTPKKSD 223
>PHO85_CANGA (Q6FKD4) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 302 Score = 147 bits (371), Expect = 3e-35 Identities = 76/185 (41%), Positives = 111/185 (60%), Gaps = 7/185 (3%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRSN------QAL 239 +REI L++ + H+NIV + D+I N + + +E MD DL + + S + L Sbjct: 50 IREISLMKELKHDNIVRLYDVIHTE-----NKLTLVFEYMDNDLKKYMDSRTVGNAPRGL 104 Query: 240 SEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFM 416 +YF +Q+L GL + H +LHRDLKP NLL+ LK+ DFGLAR + Sbjct: 105 EMNLVKYFQWQLLEGLAFCHENKILHRDLKPQNLLITKRGQLKLGDFGLARAFGIPVNTF 164 Query: 417 TEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELI 596 + VVT WYRAP++L+ S Y+ +ID+WS GCI E++ KPLFPG + QL+L+ + + Sbjct: 165 SSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKLIFDKM 224 Query: 597 GTPNE 611 GTPNE Sbjct: 225 GTPNE 229
>CD2L7_HUMAN (Q9NYV4) Cell division cycle 2-related protein kinase 7 (EC| 2.7.11.22) (CDC2-related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS) Length = 1490 Score = 147 bits (371), Expect = 3e-35 Identities = 80/187 (42%), Positives = 113/187 (60%), Gaps = 11/187 (5%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQ--------RTAFNDVYIAYELMDTDLHQIIRSNQ 233 +REIK+LR + H ++V +++I+ Q + AF Y+ +E MD DL ++ S Sbjct: 772 IREIKILRQLIHRSVVNMKEIVTDKQDALDFKKDKGAF---YLVFEYMDHDLMGLLESGL 828 Query: 234 A-LSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLAR--TTSE 404 SE+H + F+ Q++ GL+Y H N LHRD+K SN+LLN + +K+ DFGLAR + E Sbjct: 829 VHFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEE 888 Query: 405 TDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLL 584 + T V+T WYR PELLL YT AIDVWS GCI EL +KP+F + QL L+ Sbjct: 889 SRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELI 948 Query: 585 MELIGTP 605 L G+P Sbjct: 949 SRLCGSP 955
>MAK_HUMAN (P20794) Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male| germ cell-associated kinase) Length = 623 Score = 147 bits (370), Expect = 3e-35 Identities = 77/187 (41%), Positives = 115/187 (61%), Gaps = 2/187 (1%) Frame = +3 Query: 63 DAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFND-VYIAYELMDTDLHQIIRS-NQA 236 D LRE+K L+ ++H N++ ++++I ND +Y +E M +L+Q+++ N+ Sbjct: 43 DECMNLREVKSLKKLNHANVIKLKEVIRE------NDHLYFIFEYMKENLYQLMKDRNKL 96 Query: 237 LSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTSETDFM 416 E + +YQIL+GL +IH HRD+KP NLL +KI DFGLAR Sbjct: 97 FPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPY 156 Query: 417 TEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELI 596 T+YV TRWYRAPE+LL SS Y++ IDVW+VG I EL +PLFPG V ++ + +++ Sbjct: 157 TDYVSTRWYRAPEVLLRSSVYSSPIDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVL 216 Query: 597 GTPNEAD 617 GTP ++D Sbjct: 217 GTPKKSD 223
>CDK7_XENLA (P20911) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (40 kDa protein kinase) (P40 MO15) (CDC2/CDK2,4-activating kinase) Length = 352 Score = 147 bits (370), Expect = 3e-35 Identities = 76/183 (41%), Positives = 111/183 (60%), Gaps = 2/183 (1%) Frame = +3 Query: 69 KRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRSNQ-ALSE 245 + LREIKLL+ + H NI+ + D +++ + ++ M+TDL II+ L+ Sbjct: 63 RTALREIKLLQELSHPNIIGLLDAFGHK-----SNISLVFDFMETDLEVIIKDTSLVLTP 117 Query: 246 EHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTT-SETDFMTE 422 H + ++ L+GL+Y+H +LHRDLKP+NLLL+ N LK+ DFGLA++ S T Sbjct: 118 AHIKSYMLMTLQGLEYLHHLWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRIYTH 177 Query: 423 YVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGT 602 VVTRWYR+PELL + Y +D+W+VGCI EL+ R P PG + QL + E +GT Sbjct: 178 QVVTRWYRSPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGT 237 Query: 603 PNE 611 P E Sbjct: 238 PTE 240
>PHO85_KLULA (Q92241) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 304 Score = 147 bits (370), Expect = 3e-35 Identities = 77/196 (39%), Positives = 117/196 (59%), Gaps = 7/196 (3%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQII------RSNQAL 239 +REI L++ + H+NIV + D+I N + + +E MD DL + + S++ L Sbjct: 51 IREISLMKELKHDNIVRLFDVIHTE-----NKLTLVFEFMDNDLKKFMDNRNKGNSHKGL 105 Query: 240 SEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFM 416 + +YF +Q+L+G+ + H +LHRDLKP NLL+N LK+ DFGLAR + Sbjct: 106 EMDLVKYFQWQLLQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTF 165 Query: 417 TEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELI 596 + VVT WYRAP++L+ S Y +ID+WS GCI E++ KPLFPG + QL+L+ + + Sbjct: 166 SSEVVTLWYRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTM 225 Query: 597 GTPNEADLDFVNENAR 644 GTP E V + A+ Sbjct: 226 GTPVEQTWPQVTQLAK 241
>CD2L2_HUMAN (Q9UQ88) PITSLRE serine/threonine-protein kinase CDC2L2 (EC| 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11) Length = 780 Score = 146 bits (368), Expect = 6e-35 Identities = 78/181 (43%), Positives = 113/181 (62%), Gaps = 2/181 (1%) Frame = +3 Query: 75 TLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRS-NQALSEEH 251 +LREI + H NIV +R+I+ + + +YI ++ DL ++ + Q Sbjct: 467 SLREINTILKAQHPNIVTVREIVVGSN---MDKIYIVMNYVEHDLKSLMETMKQPFLPGE 523 Query: 252 CQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTT-SETDFMTEYV 428 + + Q+LRG+K++H +LHRDLK SNLLL+ LK+ DFGLAR S T V Sbjct: 524 VKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVV 583 Query: 429 VTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPN 608 VT+WYRAPELLL + EY+ A+D+WSVGCIF EL+ +KPLFPG + Q+ + + +GTP+ Sbjct: 584 VTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPS 643 Query: 609 E 611 E Sbjct: 644 E 644
>AL2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.11.22)| (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein) Length = 384 Score = 146 bits (368), Expect = 6e-35 Identities = 77/181 (42%), Positives = 112/181 (61%), Gaps = 3/181 (1%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRSNQA-LSEEHC 254 +RE LL+ + H NIV + DII + F +E M TDL Q + + L + Sbjct: 96 IREASLLKGLKHANIVLLHDIIHTKETLTF-----VFEYMHTDLAQYMSQHPGGLHPHNV 150 Query: 255 QYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEYVV 431 + F++Q+LRGL YIH +VLHRDLKP NLL++ +LK+ DFGLAR S + + VV Sbjct: 151 RLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVV 210 Query: 432 TRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHV-HQLRLLMELIGTPN 608 T WYR P+ LL ++EY++ +D+W GCIF+E+ +PLFPG ++ QL + E++G P Sbjct: 211 TLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPT 270 Query: 609 E 611 E Sbjct: 271 E 271
>CDKL1_HUMAN (Q00532) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| (Serine/threonine-protein kinase KKIALRE) (Protein kinase p42 KKIALRE) Length = 357 Score = 146 bits (368), Expect = 6e-35 Identities = 69/191 (36%), Positives = 118/191 (61%), Gaps = 2/191 (1%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMD-TDL 209 K + D+ + K LREI++L+ + H N+V + ++ +R +++ +E D T L Sbjct: 34 KFLESEDDPVIKKIALREIRMLKQLKHPNLVNLLEVFRRKRR-----LHLVFEYCDHTVL 88 Query: 210 HQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLA 389 H++ R + + E + +Q L+ + + H N +HRD+KP N+L+ + +K+CDFG A Sbjct: 89 HELDRYQRGVPEHLVKSITWQTLQAVNFCHKHNCIHRDVKPENILITKHSVIKLCDFGFA 148 Query: 390 RT-TSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHV 566 R T +D+ T+YV TRWYR+PELL+ ++Y +DVW++GC+F EL+ PL+PG+ V Sbjct: 149 RLLTGPSDYYTDYVATRWYRSPELLVGDTQYGPPVDVWAIGCVFAELLSGVPLWPGKSDV 208 Query: 567 HQLRLLMELIG 599 QL L+ + +G Sbjct: 209 DQLYLIRKTLG 219
>CDK2_HUMAN (P24941) Cell division protein kinase 2 (EC 2.7.11.22) (p33 protein| kinase) Length = 298 Score = 146 bits (368), Expect = 6e-35 Identities = 75/181 (41%), Positives = 111/181 (61%), Gaps = 3/181 (1%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRSNQ--ALSEEH 251 +REI LL+ ++H NIV + D+I N +Y+ +E + DL + + ++ + Sbjct: 49 IREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLHQDLKKFMDASALTGIPLPL 103 Query: 252 CQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEYV 428 + +L+Q+L+GL + HS VLHRDLKP NLL+N +K+ DFGLAR T V Sbjct: 104 IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEV 163 Query: 429 VTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPN 608 VT WYRAPE+LL Y+ A+D+WS+GCIF E++ R+ LFPG + QL + +GTP+ Sbjct: 164 VTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPD 223 Query: 609 E 611 E Sbjct: 224 E 224
>CDK5_RAT (Q03114) Cell division protein kinase 5 (EC 2.7.11.22) (Tau protein| kinase II catalytic subunit) (TPKII catalytic subunit) (Serine/threonine-protein kinase PSSALRE) Length = 292 Score = 145 bits (367), Expect = 8e-35 Identities = 80/181 (44%), Positives = 111/181 (61%), Gaps = 3/181 (1%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRS-NQALSEEHC 254 LREI LL+ + H+NIV + D++ ++ + +E D DL + S N L E Sbjct: 49 LREICLLKELKHKNIVRLHDVLHSDKKLT-----LVFEFCDQDLKKYFDSCNGDLDPEIV 103 Query: 255 QYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEYVV 431 + L+Q+L+GL + HS NVLHRDLKP NLL+N N +LK+ DFGLAR + VV Sbjct: 104 KSLLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVV 163 Query: 432 TRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDR-KPLFPGRDHVHQLRLLMELIGTPN 608 T WYR P++L + Y+ +ID+WS GCIF EL + +PLFPG D QL+ + L+GTP Sbjct: 164 TLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPT 223 Query: 609 E 611 E Sbjct: 224 E 224
>CD2L5_HUMAN (Q14004) Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22)| (CDC2-related protein kinase 5) (Cholinesterase-related cell division controller) Length = 1512 Score = 145 bits (367), Expect = 8e-35 Identities = 77/187 (41%), Positives = 112/187 (59%), Gaps = 11/187 (5%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQ--------RTAFNDVYIAYELMDTDLHQIIRSNQ 233 +REIK+LR + H++I+ +++I+ + + AF Y+ +E MD DL ++ S Sbjct: 750 IREIKILRQLTHQSIINMKEIVTDKEDALDFKKDKGAF---YLVFEYMDHDLMGLLESGL 806 Query: 234 A-LSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLAR--TTSE 404 +E H + F+ Q++ GL Y H N LHRD+K SN+LLN +K+ DFGLAR ++ E Sbjct: 807 VHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEE 866 Query: 405 TDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLL 584 + T V+T WYR PELLL YT AIDVWS GCI EL +KP+F + QL L+ Sbjct: 867 SRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELI 926 Query: 585 MELIGTP 605 + G+P Sbjct: 927 SRICGSP 933
>CDC2_CHICK (P13863) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 145 bits (367), Expect = 8e-35 Identities = 77/181 (42%), Positives = 109/181 (60%), Gaps = 4/181 (2%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQI---IRSNQALSEE 248 +REI LL+ + H NIV ++D++ R +Y+ +E + DL + I S Q L Sbjct: 49 IREISLLKELHHPNIVCLQDVLMQDAR-----LYLIFEFLSMDLKKYLDTIPSGQYLDRS 103 Query: 249 HCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEY 425 + +LYQIL+G+ + HS VLHRDLKP NLL++ +K+ DFGLAR T Sbjct: 104 RVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGVIKLADFGLARAFGIPVRVYTHE 163 Query: 426 VVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTP 605 VVT WYR+PE+LL S+ Y+ +D+WS+G IF EL +KPLF G + QL + +GTP Sbjct: 164 VVTLWYRSPEVLLGSALYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTP 223 Query: 606 N 608 N Sbjct: 224 N 224
>CD2L7_CAEEL (P46551) Putative cell division cycle 2-related protein kinase 7| (EC 2.7.11.22) Length = 730 Score = 145 bits (367), Expect = 8e-35 Identities = 82/187 (43%), Positives = 112/187 (59%), Gaps = 10/187 (5%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDII------PPAQRTAFNDVYIAYELMDTDLHQIIRSNQAL 239 +REIK+LR + H+NIV + DI+ +RT N Y+ +E +D DL ++ S + + Sbjct: 356 IREIKILRQLHHKNIVRLMDIVIDDISMDELKRTRAN-FYLVFEYVDHDLIGLLESKELV 414 Query: 240 S---EEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLART-TSET 407 ++ C F Q+L GL YIH+ LHRD+K SN+L+N +LKI D GLAR E+ Sbjct: 415 DFNKDQICSLFK-QLLEGLAYIHNTGFLHRDIKCSNILVNNKGELKIADLGLARLWEKES 473 Query: 408 DFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLM 587 T V+T WYR PELLL Y AIDVWS GC+ EL RKPLF G + QL L+ Sbjct: 474 RLYTNRVITLWYRPPELLLGDERYGPAIDVWSTGCMLGELFTRKPLFNGNNEFGQLELIS 533 Query: 588 ELIGTPN 608 ++ G+PN Sbjct: 534 KVCGSPN 540
>CD2L5_MOUSE (Q69ZA1) Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22)| (CDC2-related protein kinase 5) Length = 1511 Score = 145 bits (367), Expect = 8e-35 Identities = 77/187 (41%), Positives = 112/187 (59%), Gaps = 11/187 (5%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQ--------RTAFNDVYIAYELMDTDLHQIIRSNQ 233 +REIK+LR + H++I+ +++I+ + + AF Y+ +E MD DL ++ S Sbjct: 750 IREIKILRQLTHQSIINMKEIVTDKEDALDFKKDKGAF---YLVFEYMDHDLMGLLESGL 806 Query: 234 A-LSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLAR--TTSE 404 +E H + F+ Q++ GL Y H N LHRD+K SN+LLN +K+ DFGLAR ++ E Sbjct: 807 VHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEE 866 Query: 405 TDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLL 584 + T V+T WYR PELLL YT AIDVWS GCI EL +KP+F + QL L+ Sbjct: 867 SRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELI 926 Query: 585 MELIGTP 605 + G+P Sbjct: 927 SRICGSP 933
>BUR1_NEUCR (Q871M9) Serine/threonine-protein kinase bur-1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 545 Score = 145 bits (366), Expect = 1e-34 Identities = 78/196 (39%), Positives = 117/196 (59%), Gaps = 18/196 (9%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDII----PPAQRTAFNDVYIAYELMDTDLHQIIRSNQA-LS 242 LREIKLL+ + H+N++ + ++ P + VY+ MD DL ++ + + Sbjct: 71 LREIKLLKLLSHKNVLRLEEMAIEHPPRTDKRTRPIVYMVTPYMDHDLSGLLDNPSVRFT 130 Query: 243 EEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLART--------- 395 E + +L Q+L GLKY+H+ ++LHRD+K +NLL+N L+I DFGLAR Sbjct: 131 EPQVKCYLLQLLEGLKYLHANHILHRDMKAANLLINNKGVLQIADFGLARHYEGDIPQPG 190 Query: 396 ----TSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDH 563 + D+ T VVTRWYR PELL++ YT AID+W VGC+F E+++ KP+ G Sbjct: 191 KGSGEGKRDY-TSLVVTRWYRPPELLMHLKRYTTAIDMWGVGCVFAEMLEGKPVLQGESD 249 Query: 564 VHQLRLLMELIGTPNE 611 +HQL L+ +L GTP+E Sbjct: 250 LHQLELVWDLCGTPSE 265
>KIN28_YEAST (P06242) Serine/threonine-protein kinase KIN28 (EC 2.7.11.23)| Length = 306 Score = 145 bits (366), Expect = 1e-34 Identities = 74/182 (40%), Positives = 112/182 (61%), Gaps = 2/182 (1%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRSNQAL-SEEHC 254 +RE+K L+ M H N++ + DI A++++ + E + TDL +I+ L + Sbjct: 52 IREVKYLQEMQHPNVIELIDIF-----MAYDNLNLVLEFLPTDLEVVIKDKSILFTPADI 106 Query: 255 QYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTT-SETDFMTEYVV 431 + ++ LRG+ + H +LHRDLKP+NLL + + +K+ DFGLAR + + +T VV Sbjct: 107 KAWMLMTLRGVYHCHRNFILHRDLKPNNLLFSPDGQIKVADFGLARAIPAPHEILTSNVV 166 Query: 432 TRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPNE 611 TRWYRAPELL + YT+AID+WSVG IF ELM R P PG++ V Q+ + +GTP + Sbjct: 167 TRWYRAPELLFGAKHYTSAIDIWSVGVIFAELMLRIPYLPGQNDVDQMEVTFRALGTPTD 226 Query: 612 AD 617 D Sbjct: 227 RD 228
>CDC2_RANDY (Q9W739) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 302 Score = 145 bits (366), Expect = 1e-34 Identities = 79/181 (43%), Positives = 109/181 (60%), Gaps = 4/181 (2%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQI---IRSNQALSEE 248 +REI LL+ + H NIV + D++ R +Y+ +E + DL + I S Q L Sbjct: 49 IREISLLKELQHPNIVCLLDVLMQDSR-----LYLIFEFLSMDLKKYLDSIPSGQYLEAM 103 Query: 249 HCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEY 425 + +LYQIL+G+ + H+ VLHRDLKP NLL+++ +K+ DFGLAR T Sbjct: 104 LVKSYLYQILQGIIFCHARRVLHRDLKPQNLLIDSKGVIKLADFGLARAFGIPVRVYTHE 163 Query: 426 VVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTP 605 VVT WYRAPE+LL S Y+ +DVWS+G IF E+ +KPLF G + QL + EL GTP Sbjct: 164 VVTLWYRAPEVLLGSVRYSTPVDVWSIGTIFAEIASKKPLFHGDSEIDQLFRISELWGTP 223 Query: 606 N 608 N Sbjct: 224 N 224
>CD2L1_HUMAN (P21127) PITSLRE serine/threonine-protein kinase CDC2L1 (EC| 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1) Length = 795 Score = 145 bits (366), Expect = 1e-34 Identities = 78/181 (43%), Positives = 113/181 (62%), Gaps = 2/181 (1%) Frame = +3 Query: 75 TLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRS-NQALSEEH 251 +LREI + H NIV +R+I+ + + +YI ++ DL ++ + Q Sbjct: 482 SLREINTILKAQHPNIVTVREIVVGSN---MDKIYIVMNYVEHDLKSLMETMKQPFLPGE 538 Query: 252 CQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTT-SETDFMTEYV 428 + + Q+LRG+K++H +LHRDLK SNLLL+ LK+ DFGLAR S T V Sbjct: 539 VKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVV 598 Query: 429 VTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPN 608 VT WYRAPELLL + EY+ A+D+WSVGCIF EL+ +KPLFPG+ + Q+ + + +GTP+ Sbjct: 599 VTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPS 658 Query: 609 E 611 E Sbjct: 659 E 659
>CTK1_YEAST (Q03957) CTD kinase subunit alpha (EC 2.7.11.23) (CTD kinase 58 kDa| subunit) (CTDK-I alpha subunit) Length = 528 Score = 145 bits (366), Expect = 1e-34 Identities = 67/178 (37%), Positives = 113/178 (63%), Gaps = 1/178 (0%) Frame = +3 Query: 75 TLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRSNQA-LSEEH 251 ++REIKLL+ DH N+ I++I+ +Q+T VY+ +E D DL ++ + + +S Sbjct: 227 SIREIKLLQSFDHPNVSTIKEIMVESQKT----VYMIFEYADNDLSGLLLNKEVQISHSQ 282 Query: 252 CQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTSETDFMTEYVV 431 C++ Q+L G++Y+H +LHRD+K SN+L++ +LKI DFGLAR + T V+ Sbjct: 283 CKHLFKQLLLGMEYLHDNKILHRDVKGSNILIDNQGNLKITDFGLARKMNSRADYTNRVI 342 Query: 432 TRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTP 605 T WYR PELLL ++ Y +D+W GC+ +EL ++ +F G + + Q+ + +++GTP Sbjct: 343 TLWYRPPELLLGTTNYGTEVDMWGCGCLLVELFNKTAIFQGSNELEQIESIFKIMGTP 400
>CDC2_RAT (P39951) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 145 bits (365), Expect = 1e-34 Identities = 75/181 (41%), Positives = 110/181 (60%), Gaps = 4/181 (2%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRS---NQALSEE 248 +REI LL+ + H NIV+++D++ R +Y+ +E + DL + + S Q + Sbjct: 49 IREISLLKELRHPNIVSLQDVLMQDSR-----LYLIFEFLSMDLKKYLDSIPPGQFMDSS 103 Query: 249 HCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEY 425 + +LYQIL+G+ + HS VLHRDLKP NLL++ +K+ DFGLAR T Sbjct: 104 LVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHE 163 Query: 426 VVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTP 605 VVT WYR+PE+LL S+ Y+ +D+WS+G IF EL +KPLF G + QL + +GTP Sbjct: 164 VVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTP 223 Query: 606 N 608 N Sbjct: 224 N 224
>CDC2_PONPY (Q5RCH1) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 145 bits (365), Expect = 1e-34 Identities = 75/181 (41%), Positives = 110/181 (60%), Gaps = 4/181 (2%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRS---NQALSEE 248 +REI LL+ + H NIV+++D++ R +Y+ +E + DL + + S Q + Sbjct: 49 IREISLLKELRHPNIVSLQDVLMQDSR-----LYLIFEFLSMDLKKYLDSIPPGQYMDSS 103 Query: 249 HCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEY 425 + +LYQIL+G+ + HS VLHRDLKP NLL++ +K+ DFGLAR T Sbjct: 104 LVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHE 163 Query: 426 VVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTP 605 VVT WYR+PE+LL S+ Y+ +D+WS+G IF EL +KPLF G + QL + +GTP Sbjct: 164 VVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTP 223 Query: 606 N 608 N Sbjct: 224 N 224
>CDC2_HUMAN (P06493) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 145 bits (365), Expect = 1e-34 Identities = 75/181 (41%), Positives = 110/181 (60%), Gaps = 4/181 (2%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRS---NQALSEE 248 +REI LL+ + H NIV+++D++ R +Y+ +E + DL + + S Q + Sbjct: 49 IREISLLKELRHPNIVSLQDVLMQDSR-----LYLIFEFLSMDLKKYLDSIPPGQYMDSS 103 Query: 249 HCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEY 425 + +LYQIL+G+ + HS VLHRDLKP NLL++ +K+ DFGLAR T Sbjct: 104 LVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHE 163 Query: 426 VVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTP 605 VVT WYR+PE+LL S+ Y+ +D+WS+G IF EL +KPLF G + QL + +GTP Sbjct: 164 VVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTP 223 Query: 606 N 608 N Sbjct: 224 N 224
>PIT1_SCHPO (O14132) Sporulation protein kinase pit1 (EC 2.7.11.1)| Length = 650 Score = 145 bits (365), Expect = 1e-34 Identities = 80/193 (41%), Positives = 117/193 (60%), Gaps = 8/193 (4%) Frame = +3 Query: 57 KIDAKRTLREI-KLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQII--RS 227 K+ LRE+ LLR ++ENIV I D+ F ++I E +D +L+Q+I R Sbjct: 74 KVSDATRLREVHSLLRLSENENIVNIFDLYIDQ----FRCLHIVMEFLDCNLYQLISTRK 129 Query: 228 NQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCD-----LKICDFGLAR 392 N L+ E Q + QI +GL +IH+ HRD+KP N+L+++N D +KI DFGLAR Sbjct: 130 NDPLTLEQVQDIMRQIFKGLNHIHTNGFFHRDMKPENILISSNSDSSSFNVKIADFGLAR 189 Query: 393 TTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQ 572 + TEYV TRWYRAPELLL S Y+ +D+++ GC+ E+ +P+FPG D Q Sbjct: 190 EINSRPPYTEYVSTRWYRAPELLLRDSYYSFPVDIYAAGCMAFEIATLQPIFPGNDDFDQ 249 Query: 573 LRLLMELIGTPNE 611 L + E++G+P+E Sbjct: 250 LYKMCEILGSPDE 262
>CDC2_BOVIN (P48734) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 144 bits (363), Expect = 2e-34 Identities = 75/181 (41%), Positives = 110/181 (60%), Gaps = 4/181 (2%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRS---NQALSEE 248 +REI LL+ + H NIV+++D++ R +Y+ +E + DL + + S Q + Sbjct: 49 IREISLLKELRHPNIVSLQDVLMQDSR-----LYLIFEFLSMDLKKYLDSIPPGQFMDSS 103 Query: 249 HCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEY 425 + +LYQIL+G+ + HS VLHRDLKP NLL++ +K+ DFGLAR T Sbjct: 104 LVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHE 163 Query: 426 VVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTP 605 VVT WYR+PE+LL S+ Y+ +D+WS+G IF EL +KPLF G + QL + +GTP Sbjct: 164 VVTLWYRSPEVLLGSAGYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTP 223 Query: 606 N 608 N Sbjct: 224 N 224
>PHO85_ASHGO (Q751E8) Negative regulator of the PHO system (EC 2.7.11.22)| (Serine/threonine-protein kinase PHO85) Length = 303 Score = 144 bits (363), Expect = 2e-34 Identities = 76/185 (41%), Positives = 110/185 (59%), Gaps = 7/185 (3%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRSN------QAL 239 +REI L++ + HENIV + D+I N + + +E MD DL + + S + L Sbjct: 53 IREISLMKELKHENIVRLYDVIHTE-----NKLTLVFEFMDNDLKKFMDSRLDREMPRGL 107 Query: 240 SEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFM 416 +YF +Q+L+G+ + H +LHRDLKP NLL+N LK+ DFGLAR + Sbjct: 108 ELSLVKYFQWQLLQGVAFCHENRILHRDLKPQNLLINNKGQLKLGDFGLARAFGIPVNTF 167 Query: 417 TEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELI 596 + VVT WYRAP++L+ S Y +ID+WS GCI E++ K LFPG + QL+L+ E + Sbjct: 168 SSEVVTLWYRAPDVLMGSRTYCTSIDIWSCGCILAEMIMGKALFPGTNDDEQLKLIFETM 227 Query: 597 GTPNE 611 GTP E Sbjct: 228 GTPTE 232
>CDC21_XENLA (P35567) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| (EC 2.7.11.23) (p34 protein kinase 1) Length = 302 Score = 144 bits (363), Expect = 2e-34 Identities = 77/181 (42%), Positives = 108/181 (59%), Gaps = 4/181 (2%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQI---IRSNQALSEE 248 +REI LL+ + H NIV + D++ R +Y+ +E + DL + I S Q + Sbjct: 49 IREISLLKELQHPNIVCLLDVLMQDSR-----LYLIFEFLSMDLKKYLDSIPSGQYIDTM 103 Query: 249 HCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEY 425 + +LYQIL+G+ + HS VLHRDLKP NLL+++ +K+ DFGLAR T Sbjct: 104 LVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDSKGVIKLADFGLARAFGIPVRVYTHE 163 Query: 426 VVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTP 605 VVT WYRAPE+LL S Y+ +DVWS+G IF E+ +KPLF G + QL + +GTP Sbjct: 164 VVTLWYRAPEVLLGSVRYSTPVDVWSIGTIFAEIATKKPLFHGDSEIDQLFRIFRALGTP 223 Query: 606 N 608 N Sbjct: 224 N 224
>CDC2_DROME (P23572) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) Length = 297 Score = 144 bits (362), Expect = 3e-34 Identities = 75/197 (38%), Positives = 113/197 (57%), Gaps = 4/197 (2%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLH 212 KI D++ +REI LL+ + HENIV + D++ R +Y+ +E + DL Sbjct: 34 KIRLESDDEGVPSTAIREISLLKELKHENIVCLEDVLMEENR-----IYLIFEFLSMDLK 88 Query: 213 QIIRS---NQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFG 383 + + S ++ + E + +LYQI + + H VLHRDLKP NLL++ + +K+ DFG Sbjct: 89 KYMDSLPVDKHMESELVRSYLYQITSAILFCHRRRVLHRDLKPQNLLIDKSGLIKVADFG 148 Query: 384 LARTTS-ETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRD 560 L R+ T +VT WYRAPE+LL S Y+ +D+WS+GCIF E+ RKPLF G Sbjct: 149 LGRSFGIPVRIYTHEIVTLWYRAPEVLLGSPRYSCPVDIWSIGCIFAEMATRKPLFQGDS 208 Query: 561 HVHQLRLLMELIGTPNE 611 + QL + ++ TP E Sbjct: 209 EIDQLFRMFRILKTPTE 225
>CDKL1_MOUSE (Q8CEQ0) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| Length = 352 Score = 144 bits (362), Expect = 3e-34 Identities = 68/185 (36%), Positives = 114/185 (61%), Gaps = 2/185 (1%) Frame = +3 Query: 51 DNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMD-TDLHQIIRS 227 D+ + K LREI++L+ + H N+V + ++ +R +++ +E D T LH++ R Sbjct: 40 DDPVIKKIALREIRMLKQLKHPNLVNLLEVFRRKRR-----LHLVFEYCDHTVLHELDRY 94 Query: 228 NQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLART-TSE 404 + + E + +Q L+ + + H N +HRD+KP N+L+ +K+CDFG AR T Sbjct: 95 QRGVPEPLVKNITWQTLQAVNFCHKHNCIHRDVKPENILITKQSAIKLCDFGFARLLTGP 154 Query: 405 TDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLL 584 D+ T+YV TRWYR+PELL+ ++Y +DVW++GC+F EL+ PL+PG+ V QL L+ Sbjct: 155 GDYYTDYVATRWYRSPELLVGDTQYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLI 214 Query: 585 MELIG 599 + +G Sbjct: 215 RKTLG 219
>CDC2H_DICDI (P34117) CDC2-like serine/threonine-protein kinase CRP (EC| 2.7.11.22) (EC 2.7.11.23) Length = 292 Score = 143 bits (361), Expect = 4e-34 Identities = 74/188 (39%), Positives = 111/188 (59%), Gaps = 2/188 (1%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQII-RSNQALSEEHC 254 +REI LL+ + H NIV + D+I ++ + +E +D DL + + +S+ Sbjct: 49 IREISLLKELKHPNIVRLHDVIHTERKLT-----LVFEYLDQDLKKYLDECGGEISKPTI 103 Query: 255 QYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEYVV 431 + F+YQ+L+G+ + H VLHRDLKP NLL+N +LK+ DFGLAR + VV Sbjct: 104 KSFMYQLLKGVAFCHDHRVLHRDLKPQNLLINRKGELKLADFGLARAFGIPVRTYSHEVV 163 Query: 432 TRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPNE 611 T WYRAP++L+ S +Y+ ID+WS CIF E+ +PLFPG QL + +++GTPNE Sbjct: 164 TLWYRAPDVLMGSRKYSTPIDIWSALCIFAEMASGRPLFPGSGTSDQLFRIFKILGTPNE 223 Query: 612 ADLDFVNE 635 + E Sbjct: 224 ESWPSITE 231
>PFTK1_MOUSE (O35495) Serine/threonine-protein kinase PFTAIRE-1 (EC 2.7.11.22)| Length = 469 Score = 143 bits (361), Expect = 4e-34 Identities = 77/181 (42%), Positives = 112/181 (61%), Gaps = 3/181 (1%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRSNQA-LSEEHC 254 +RE LL+ + H NIV + DII + + +E + TDL Q + + L ++ Sbjct: 179 IREASLLKGLKHANIVLLHDIIHTKETLT-----LVFEYVHTDLCQYMEQHPGGLHPDNV 233 Query: 255 QYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEYVV 431 + FL+Q+LRGL YIH +LHRDLKP NLL++ +LK+ DFGLAR S + + VV Sbjct: 234 KLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVV 293 Query: 432 TRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPG-RDHVHQLRLLMELIGTPN 608 T WYR P++LL S+EY+ +D+W VGCIF+E++ FPG +D QL + ++GTPN Sbjct: 294 TLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPN 353 Query: 609 E 611 E Sbjct: 354 E 354
>CDC2D_ANTMA (Q38775) Cell division control protein 2 homolog D (EC 2.7.11.22)| (EC 2.7.11.23) Length = 312 Score = 143 bits (361), Expect = 4e-34 Identities = 77/186 (41%), Positives = 115/186 (61%), Gaps = 7/186 (3%) Frame = +3 Query: 75 TLREIKLLRHMDHE-NIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRS----NQAL 239 TLRE+ LLR + + ++V + D+ + +Y+ +E MDTDL + IRS +++ Sbjct: 58 TLREVSLLRMLSRDPHVVRLLDVKQGQNKEGKTVLYLVFEYMDTDLKKYIRSFKQTGESI 117 Query: 240 SEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCD-LKICDFGLART-TSETDF 413 + + + +YQ+ +G+ + H VLHRDLKP NLL++ LKI D GLAR T Sbjct: 118 APMNVKSLMYQLCKGVAFCHGHGVLHRDLKPHNLLMDRKTMMLKIADLGLARAYTLPIKK 177 Query: 414 MTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMEL 593 T ++T WYRAPE+LL ++ Y+ A+D+WSV CIF EL+ +K LFPG + QL + L Sbjct: 178 YTHEILTLWYRAPEVLLGATHYSPAVDMWSVACIFAELVTQKALFPGDSELQQLLHIFRL 237 Query: 594 IGTPNE 611 +GTPNE Sbjct: 238 LGTPNE 243
>CDC2_MOUSE (P11440) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 297 Score = 143 bits (360), Expect = 5e-34 Identities = 74/181 (40%), Positives = 110/181 (60%), Gaps = 4/181 (2%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRS---NQALSEE 248 +REI LL+ + H NIV+++D++ R +Y+ +E + DL + + S Q + Sbjct: 49 IREISLLKELRHPNIVSLQDVLMQDSR-----LYLIFEFLSMDLKKYLDSIPPGQFMDSS 103 Query: 249 HCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEY 425 + +L+QIL+G+ + HS VLHRDLKP NLL++ +K+ DFGLAR T Sbjct: 104 LVKSYLHQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHE 163 Query: 426 VVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTP 605 VVT WYR+PE+LL S+ Y+ +D+WS+G IF EL +KPLF G + QL + +GTP Sbjct: 164 VVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTP 223 Query: 606 N 608 N Sbjct: 224 N 224
>CDKL4_HUMAN (Q5MAI5) Cyclin-dependent kinase-like 4 (EC 2.7.11.22)| Length = 315 Score = 143 bits (360), Expect = 5e-34 Identities = 67/190 (35%), Positives = 119/190 (62%), Gaps = 1/190 (0%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMD-TDL 209 K + D+ + K LREI++L+ + H N+V + ++ ++ +++ +E D T L Sbjct: 34 KFVESEDDPVVKKIALREIRMLKQLKHPNLVNLIEVFRRKRK-----MHLVFEYCDHTLL 88 Query: 210 HQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLA 389 +++ R+ +++ + L+Q L+ L + H N +HRD+KP N+L+ +KICDFG A Sbjct: 89 NELERNPNGVADGVIKSVLWQTLQALNFCHIHNCIHRDIKPENILITKQGIIKICDFGFA 148 Query: 390 RTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVH 569 + D T+YV TRWYRAPELL+ ++Y +++D+W++GC+F EL+ +PL+PG+ V Sbjct: 149 QILIPGDAYTDYVATRWYRAPELLVGDTQYGSSVDIWAIGCVFAELLTGQPLWPGKSDVD 208 Query: 570 QLRLLMELIG 599 QL L++ +G Sbjct: 209 QLYLIIRTLG 218
>CD2L1_MOUSE (P24788) PITSLRE serine/threonine-protein kinase CDC2L1 (EC| 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) Length = 784 Score = 143 bits (360), Expect = 5e-34 Identities = 77/181 (42%), Positives = 112/181 (61%), Gaps = 2/181 (1%) Frame = +3 Query: 75 TLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRS-NQALSEEH 251 +LREI + H NIV +R+I+ + + +YI ++ DL ++ + Q Sbjct: 471 SLREINTILKAQHPNIVTVREIVVGSN---MDKIYIVMNYVEHDLKSLMETMKQPFLPGE 527 Query: 252 CQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTT-SETDFMTEYV 428 + + Q+L G+K++H +LHRDLK SNLLL+ LK+ DFGLAR S T V Sbjct: 528 VKTLMIQLLSGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVV 587 Query: 429 VTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPN 608 VT WYRAPELLL + EY+ A+D+WSVGCIF EL+ +KPLFPG+ + Q+ + + +GTP+ Sbjct: 588 VTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSDIDQINKIFKDLGTPS 647 Query: 609 E 611 E Sbjct: 648 E 648
>KC47_ORYSA (P29620) CDC2+/CDC28-related protein kinase R2 (EC 2.7.11.22)| Length = 424 Score = 142 bits (359), Expect = 6e-34 Identities = 75/182 (41%), Positives = 110/182 (60%), Gaps = 3/182 (1%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRS-NQALSEEHC 254 LREIKLL+ + NI+ + D P ++++ +E M+TDL +IR N LS Sbjct: 64 LREIKLLKELKDSNIIELIDAFPYK-----GNLHLVFEFMETDLEAVIRDRNIVLSPADT 118 Query: 255 QYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLART--TSETDFMTEYV 428 + ++ +L+GL + H VLHRD+KP+NLL+ A+ LK+ DFGLAR + E +F T V Sbjct: 119 KSYIQMMLKGLAFCHKKWVLHRDMKPNNLLIGADGQLKLADFGLARIFGSPERNF-THQV 177 Query: 429 VTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPN 608 RWYRAPELL + +Y +A+D+W+ GCIF EL+ R+P G + QL + GTP Sbjct: 178 FARWYRAPELLFGTKQYGSAVDIWAAGCIFAELLLRRPFLQGSSDIDQLGKIFAAFGTPK 237 Query: 609 EA 614 + Sbjct: 238 SS 239
>PFTK1_HUMAN (O94921) Serine/threonine-protein kinase PFTAIRE-1 (EC 2.7.11.22)| Length = 469 Score = 142 bits (359), Expect = 6e-34 Identities = 77/181 (42%), Positives = 112/181 (61%), Gaps = 3/181 (1%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRSNQA-LSEEHC 254 +RE LL+ + H NIV + DII + + +E + TDL Q + + L ++ Sbjct: 179 IREASLLKGLKHANIVLLHDIIHTKETLT-----LVFEYVHTDLCQYMDKHPGGLHPDNV 233 Query: 255 QYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEYVV 431 + FL+Q+LRGL YIH +LHRDLKP NLL++ +LK+ DFGLAR S + + VV Sbjct: 234 KLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVV 293 Query: 432 TRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPG-RDHVHQLRLLMELIGTPN 608 T WYR P++LL S+EY+ +D+W VGCIF+E++ FPG +D QL + ++GTPN Sbjct: 294 TLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPN 353 Query: 609 E 611 E Sbjct: 354 E 354
>CRK1_LEIME (Q06309) Cell division protein kinase 2 homolog CRK1 (EC 2.7.11.23)| Length = 301 Score = 142 bits (359), Expect = 6e-34 Identities = 76/179 (42%), Positives = 106/179 (59%), Gaps = 2/179 (1%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQII-RSNQALSEEHC 254 +REI LL+ + HENIV + D+ R I +E +D DL + + R N L Sbjct: 50 IREISLLKELRHENIVKLLDVCHSEHRLT-----IVFEYLDLDLKKYLDRENGNLDAATI 104 Query: 255 QYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEYVV 431 Q+F+ +LRG+ + H +VLHRDLKP NLL++ +LK+ DFGL R+ + T VV Sbjct: 105 QHFMRDLLRGVAFCHQRSVLHRDLKPQNLLISREKELKLGDFGLGRSFAIPVRKFTNEVV 164 Query: 432 TRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPN 608 T WYR P++LL S +Y +DVWSVGCIF E+ PLF G++ QL + +GTPN Sbjct: 165 TLWYRPPDVLLGSMQYGPPVDVWSVGCIFSEMATGTPLFAGKNDADQLMRIFRFLGTPN 223
>CDKL1_RAT (Q66HE7) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| Length = 352 Score = 142 bits (358), Expect = 8e-34 Identities = 67/185 (36%), Positives = 115/185 (62%), Gaps = 2/185 (1%) Frame = +3 Query: 51 DNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMD-TDLHQIIRS 227 D+ + K LREI++L+ + H N+V++ ++ +R +++ +E T LH++ R Sbjct: 40 DDPVIKKIALREIRMLKQLKHPNLVSLLEVFRRKRR-----LHLVFEYCHHTVLHELDRY 94 Query: 228 NQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLART-TSE 404 + + E + +Q L+ + + H N +HRD+KP N+L+ + +K+CDFG AR T Sbjct: 95 QRGVPEPLVKNITWQTLQAVNFCHKHNCIHRDVKPENILITKHSVIKLCDFGFARLLTGP 154 Query: 405 TDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLL 584 D+ T+YV TRWYR+PELL+ ++Y +DVW++GC+F EL+ PL+PG+ V QL L+ Sbjct: 155 GDYYTDYVATRWYRSPELLVGDTQYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLI 214 Query: 585 MELIG 599 + +G Sbjct: 215 RKTLG 219
>PEF1_SCHPO (O74456) Serine/threonine-protein kinase pef1 (EC 2.7.11.22)| (Cyclin-dependent kinase pef1) (PHO85 homolog) Length = 288 Score = 142 bits (357), Expect = 1e-33 Identities = 74/182 (40%), Positives = 113/182 (62%), Gaps = 4/182 (2%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRS--NQ-ALSEE 248 +REI L++ + H NI+++ D++ N + + +E M+ DL + + + NQ AL Sbjct: 47 IREISLMKELRHPNIMSLSDVLQTE-----NKLMLVFEYMEKDLKKYMDTYGNQGALPPS 101 Query: 249 HCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEY 425 + F Q+L+G+ + H VLHRDLKP NLL+N+ +LK+ DFGLAR+ + + Sbjct: 102 QVKNFTQQLLKGISFCHENRVLHRDLKPQNLLINSRGELKLADFGLARSIGIPVNTFSNE 161 Query: 426 VVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTP 605 VVT WYRAP++LL S Y+ +ID+WSVGCI E+ +PLF G ++ QL + L+GTP Sbjct: 162 VVTLWYRAPDVLLGSRVYSTSIDIWSVGCIMAEMATGRPLFAGSNNEDQLLKIFRLLGTP 221 Query: 606 NE 611 E Sbjct: 222 TE 223
>CDC22_XENLA (P24033) Cell division control protein 2 homolog 2 (EC 2.7.11.22)| (EC 2.7.11.23) (p34 protein kinase 2) Length = 302 Score = 142 bits (357), Expect = 1e-33 Identities = 77/181 (42%), Positives = 107/181 (59%), Gaps = 4/181 (2%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQI---IRSNQALSEE 248 +REI LL+ + H NIV + D++ R +Y+ +E + D+ + I S Q + Sbjct: 49 IREISLLKELQHPNIVCLLDVLMQDSR-----LYLIFEFLSMDVKKYLDSIPSGQYIDTM 103 Query: 249 HCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEY 425 + +LYQIL+G+ + HS VLHRDLKP NLL++ +K+ DFGLAR T Sbjct: 104 LVKSYLYQILQGIVFCHSRGVLHRDLKPQNLLIDNKGVIKLADFGLARAFGIPVRVYTHE 163 Query: 426 VVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTP 605 VVT WYRAPE+LL S Y+ +DVWSVG IF E+ +KPLF G + QL + +GTP Sbjct: 164 VVTLWYRAPEVLLGSVRYSTPVDVWSVGTIFAEIATKKPLFHGDSEIDQLFRIFRSLGTP 223 Query: 606 N 608 N Sbjct: 224 N 224
>CDKL5_HUMAN (O76039) Cyclin-dependent kinase-like 5 (EC 2.7.11.22)| (Serine/threonine-protein kinase 9) Length = 1030 Score = 141 bits (356), Expect = 1e-33 Identities = 73/207 (35%), Positives = 124/207 (59%), Gaps = 3/207 (1%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLH 212 K ++ +N+ + TLRE+K+LR + ENIV +++ + +Y+ +E ++ ++ Sbjct: 43 KFKDSEENEEVKETTLRELKMLRTLKQENIVELKEAFRRRGK-----LYLVFEYVEKNML 97 Query: 213 QIIRSN-QALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLA 389 +++ + E + ++YQ+++ + + H +++HRD+KP NLL++ N LK+CDFG A Sbjct: 98 ELLEEMPNGVPPEKVKSYIYQLIKAIHWCHKNDIVHRDIKPENLLISHNDVLKLCDFGFA 157 Query: 390 RTTSETD--FMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDH 563 R SE + TEYV TRWYR+PELLL + Y ++D+WSVGCI EL D +PLFPG Sbjct: 158 RNLSEGNNANYTEYVATRWYRSPELLL-GAPYGKSVDMWSVGCILGELSDGQPLFPGESE 216 Query: 564 VHQLRLLMELIGTPNEADLDFVNENAR 644 + QL + +++G + N R Sbjct: 217 IDQLFTIQKVLGPLPSEQMKLFYSNPR 243
>CDC2_SCHPO (P04551) Cell division control protein 2 (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinse) Length = 297 Score = 141 bits (356), Expect = 1e-33 Identities = 74/188 (39%), Positives = 113/188 (60%), Gaps = 10/188 (5%) Frame = +3 Query: 78 LREIKLLRHMDHEN----IVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQII-----RSN 230 +REI LL+ ++ EN V + DI+ A + +Y+ +E +D DL + + Sbjct: 49 IREISLLKEVNDENNRSNCVRLLDILH-----AESKLYLVFEFLDMDLKKYMDRISETGA 103 Query: 231 QALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ET 407 +L Q F YQ++ G+ + HS ++HRDLKP NLL++ +LK+ DFGLAR+ Sbjct: 104 TSLDPRLVQKFTYQLVNGVNFCHSRRIIHRDLKPQNLLIDKEGNLKLADFGLARSFGVPL 163 Query: 408 DFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLM 587 T +VT WYRAPE+LL S Y+ +D+WSVGCIF E++ R PLFPG + ++ + Sbjct: 164 RNYTHEIVTLWYRAPEVLLGSRHYSTGVDIWSVGCIFAEMIRRSPLFPGDSEIDEIFKIF 223 Query: 588 ELIGTPNE 611 +++GTPNE Sbjct: 224 QVLGTPNE 231
>CDKL1_BRARE (Q6AXJ9) Cyclin-dependent kinase-like 1 (EC 2.7.11.22)| Length = 350 Score = 141 bits (356), Expect = 1e-33 Identities = 69/191 (36%), Positives = 117/191 (61%), Gaps = 2/191 (1%) Frame = +3 Query: 33 KIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMD-TDL 209 K + D+ I K LREI++L+ + H N+V + ++ ++ +++ +E D T L Sbjct: 34 KFVESEDDPIIKKIALREIRMLKQLKHPNLVNLMEVFRRKRK-----LHLVFEYCDHTVL 88 Query: 210 HQIIRSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLA 389 +++ R + + E + ++Q L+ + + H N +HRD+KP N+L+ + +K+CDFG A Sbjct: 89 NELDRYPRGVPEHMVKSIIWQTLQAVNFCHKQNCIHRDVKPENILITKHQVIKLCDFGFA 148 Query: 390 RT-TSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHV 566 R T D+ T+ V TRWYRAPELL+ ++Y +DVW+VGC+F EL+ PL+PG+ V Sbjct: 149 RILTGPCDYYTDCVATRWYRAPELLVGDTQYGPPVDVWAVGCVFAELLSGAPLWPGKSDV 208 Query: 567 HQLRLLMELIG 599 QL L+ + +G Sbjct: 209 DQLYLIRKTLG 219
>BUR1_GIBZE (Q4I5U9) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 473 Score = 141 bits (356), Expect = 1e-33 Identities = 82/199 (41%), Positives = 118/199 (59%), Gaps = 18/199 (9%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRD--IIPPAQRTAFND---VYIAYELMDTDLHQIIRSNQA-L 239 LREIKLL+ + H+NI+ + D I P ++T VY+A MD DL ++ + Sbjct: 82 LREIKLLKLLSHKNILRLEDMAIEHPTRQTDKRKKPIVYMATPYMDHDLSGLLDNPSVQF 141 Query: 240 SEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLAR----TTSET 407 E + ++ Q+L GL+Y+H + +LHRD+K +NLL+N L+I DFGLAR T E+ Sbjct: 142 KEPQIKCYMLQLLEGLRYLHDSRILHRDMKAANLLINNKGILQIADFGLARHYDGRTPES 201 Query: 408 DF--------MTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDH 563 T VVTRWYR PELLL +YT AIDVW VGC+F E++ KP+ G Sbjct: 202 GVPMGEGKRDYTGLVVTRWYRPPELLLQLRQYTPAIDVWGVGCVFGEMLYGKPILAGESD 261 Query: 564 VHQLRLLMELIGTPNEADL 620 QL ++ +L+G+PNE ++ Sbjct: 262 AAQLDIIWDLMGSPNEENM 280
>KSG9_ARATH (Q39012) Shaggy-related protein kinase iota (EC 2.7.11.1)| (ASK-iota) Length = 407 Score = 141 bits (355), Expect = 2e-33 Identities = 73/200 (36%), Positives = 126/200 (63%), Gaps = 8/200 (4%) Frame = +3 Query: 63 DAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYI--AYELMDTDLHQIIR---- 224 D + RE++L+R MDH N+++++ T+ +++++ E + L++++R Sbjct: 104 DRRYKNRELQLMRPMDHPNVISLKHCF--FSTTSRDELFLNLVMEYVPETLYRVLRHYTS 161 Query: 225 SNQALSEEHCQYFLYQILRGLKYIHSA-NVLHRDLKPSNLLLNA-NCDLKICDFGLARTT 398 SNQ + + + + YQI RGL YIH+ V HRD+KP NLL++ +K+CDFG A+ Sbjct: 162 SNQRMPIFYVKLYTYQIFRGLAYIHTVPGVCHRDVKPQNLLVDPLTHQVKLCDFGSAKVL 221 Query: 399 SETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLR 578 + + Y+ +R+YRAPEL+ ++EYTA+ID+WS GC+ EL+ +PLFPG + V QL Sbjct: 222 VKGEPNISYICSRYYRAPELIFGATEYTASIDIWSAGCVLAELLLGQPLFPGENSVDQLV 281 Query: 579 LLMELIGTPNEADLDFVNEN 638 +++++GTP ++ +N N Sbjct: 282 EIIKVLGTPTREEIRCMNPN 301
>CD2L1_RAT (P46892) PITSLRE serine/threonine-protein kinase CDC2L1 (EC| 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) Length = 436 Score = 141 bits (355), Expect = 2e-33 Identities = 77/181 (42%), Positives = 110/181 (60%), Gaps = 2/181 (1%) Frame = +3 Query: 75 TLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRS-NQALSEEH 251 ++REI + H NIV +R+I+ + + +YI ++ DL ++ + Q Sbjct: 123 SIREINTILKAQHPNIVTVREIVVGSN---MDKIYIVMNYVEHDLKSLMETMKQPFLPGE 179 Query: 252 CQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTT-SETDFMTEYV 428 + + Q+L G+K++H +LHRDLK SNLLL LK+ DFGLAR S T V Sbjct: 180 VKTLMIQLLSGVKHLHDNWILHRDLKTSNLLLTHAGILKVGDFGLAREYGSPLKAYTPVV 239 Query: 429 VTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPN 608 VT WYRAPELLL + EY+ A D+WSVGCIF EL+ +KPLFPG+ + Q+ + + IGTP+ Sbjct: 240 VTLWYRAPELLLGAKEYSTACDMWSVGCIFGELLTQKPLFPGKSDIDQINKIFKDIGTPS 299 Query: 609 E 611 E Sbjct: 300 E 300
>KSG10_ARATH (Q39019) Shaggy-related protein kinase kappa (EC 2.7.11.1)| (ASK-kappa) (AtK-1) Length = 421 Score = 141 bits (355), Expect = 2e-33 Identities = 76/200 (38%), Positives = 122/200 (61%), Gaps = 8/200 (4%) Frame = +3 Query: 63 DAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYI--AYELMDTDLHQIIRS--- 227 D + RE+++++ +DH N VA++ RT +VY+ E + ++++ RS Sbjct: 117 DKRYKNRELQIMQMLDHPNAVALKHSF--FSRTDNEEVYLNLVLEFVPETVNRVARSYSR 174 Query: 228 -NQALSEEHCQYFLYQILRGLKYIHSA-NVLHRDLKPSNLLLNANC-DLKICDFGLARTT 398 NQ + + + + YQI R L YIH++ + HRD+KP NLL+N + LKICDFG A+ Sbjct: 175 TNQLMPLIYVKLYTYQICRALAYIHNSFGLCHRDIKPQNLLVNPHTHQLKICDFGSAKVL 234 Query: 399 SETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLR 578 + + Y+ +R+YRAPEL+ +SEYT AID+WS GC+ EL+ +PLFPG V QL Sbjct: 235 VKGEPNVSYICSRYYRAPELIFGASEYTTAIDIWSTGCVMAELLLGQPLFPGESGVDQLV 294 Query: 579 LLMELIGTPNEADLDFVNEN 638 +++++GTP ++ +N N Sbjct: 295 EIIKVLGTPTREEIKCMNPN 314
>CDC2_CARAU (P51958) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 302 Score = 141 bits (355), Expect = 2e-33 Identities = 75/181 (41%), Positives = 106/181 (58%), Gaps = 4/181 (2%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQI---IRSNQALSEE 248 +REI LL+ + H N+V + D++ + +Y+ +E + DL + I S Q + Sbjct: 49 VREISLLKELQHPNVVRLLDVLMQESK-----LYLVFEFLSMDLKKYLDSIPSGQFMDPM 103 Query: 249 HCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEY 425 + +LYQIL G+ + H VLHRDLKP NLL++ +K+ DFGLAR T Sbjct: 104 LVKSYLYQILEGILFCHCRRVLHRDLKPQNLLIDNKGVIKLADFGLARAFGVPVRVYTHE 163 Query: 426 VVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTP 605 VVT WYRAPE+LL +S Y+ +DVWS+G IF EL +KPLF G + QL + +GTP Sbjct: 164 VVTLWYRAPEVLLGASRYSTPVDVWSIGTIFAELATKKPLFHGDSEIDQLFRIFRTLGTP 223 Query: 606 N 608 N Sbjct: 224 N 224
>CCRK_RAT (Q4KM34) Cell cycle-related kinase (EC 2.7.11.22)| Length = 346 Score = 141 bits (355), Expect = 2e-33 Identities = 73/183 (39%), Positives = 115/183 (62%), Gaps = 4/183 (2%) Frame = +3 Query: 72 RTLREIKLLRHM-DHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRSNQA-LSE 245 + LREIK L+ + D + +V ++ + P +A+E M +DL +++R Q L+ Sbjct: 47 QALREIKALQEIEDSQYVVQLKAVFPHGA-----GFVLAFEFMLSDLAEVVRHAQRPLAP 101 Query: 246 EHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTSETD--FMT 419 + +L +L+G+ + H+ N++HRDLKP+NLL++A+ LKI DFGLAR S T Sbjct: 102 AQVKSYLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGGRLYT 161 Query: 420 EYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIG 599 V TRWYRAPELL + +Y +D+W+VGCI EL++ PLFPG + + QL ++ ++G Sbjct: 162 HQVATRWYRAPELLYGARQYDQGVDLWAVGCIMGELLNGSPLFPGENDIEQLCCVLRILG 221 Query: 600 TPN 608 TP+ Sbjct: 222 TPS 224
>CCRK_MOUSE (Q9JHU3) Cell cycle-related kinase (EC 2.7.11.22)| (Cyclin-kinase-activating kinase p42) (CDK-activating kinase p42) (CAK-kinase p42) (CDK-related protein kinase PNQLARE) Length = 346 Score = 141 bits (355), Expect = 2e-33 Identities = 73/183 (39%), Positives = 115/183 (62%), Gaps = 4/183 (2%) Frame = +3 Query: 72 RTLREIKLLRHM-DHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRSNQA-LSE 245 + LREIK L+ + D + +V ++ + P +A+E M +DL +++R Q L+ Sbjct: 47 QALREIKALQEIEDSQYVVQLKAVFPHGA-----GFVLAFEFMLSDLAEVVRHAQRPLAP 101 Query: 246 EHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTSETD--FMT 419 + +L +L+G+ + H+ N++HRDLKP+NLL++A+ LKI DFGLAR S T Sbjct: 102 AQVKSYLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGGRLYT 161 Query: 420 EYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIG 599 V TRWYRAPELL + +Y +D+W+VGCI EL++ PLFPG + + QL ++ ++G Sbjct: 162 HQVATRWYRAPELLYGARQYDQGVDLWAVGCIMGELLNGSPLFPGENDIEQLCCVLRILG 221 Query: 600 TPN 608 TP+ Sbjct: 222 TPS 224
>KSG6_ARATH (Q39010) Shaggy-related protein kinase dzeta (EC 2.7.11.1)| (ASK-dzeta) Length = 412 Score = 140 bits (354), Expect = 2e-33 Identities = 72/198 (36%), Positives = 122/198 (61%), Gaps = 6/198 (3%) Frame = +3 Query: 63 DAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIR----SN 230 D + RE++L+R MDH N+V+++ + + E + L+++++ SN Sbjct: 106 DRRYKNRELQLMRLMDHPNVVSLKHCFFSTTTRDELFLNLVMEYVPETLYRVLKHYTSSN 165 Query: 231 QALSEEHCQYFLYQILRGLKYIHSA-NVLHRDLKPSNLLLNANC-DLKICDFGLARTTSE 404 Q + + + + YQI RGL YIH+A V HRD+KP NLL++ + K+CDFG A+ + Sbjct: 166 QRMPIFYVKLYTYQIFRGLAYIHTAPGVCHRDIKPQNLLVDPHTHQCKLCDFGSAKVLVK 225 Query: 405 TDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLL 584 + Y+ +R+YRAPEL+ ++EYT++ID+WS GC+ EL+ +PLFPG + V QL + Sbjct: 226 GEPNISYICSRYYRAPELIFGATEYTSSIDIWSAGCVLAELLLGQPLFPGENSVDQLVEI 285 Query: 585 MELIGTPNEADLDFVNEN 638 ++++GTP ++ +N N Sbjct: 286 IKVLGTPTREEIRCMNPN 303
>CDK4_PIG (P79432) Cell division protein kinase 4 (EC 2.7.11.22)| (Cyclin-dependent kinase 4) Length = 303 Score = 140 bits (352), Expect = 4e-33 Identities = 77/186 (41%), Positives = 109/186 (58%), Gaps = 5/186 (2%) Frame = +3 Query: 75 TLREIKLLRHMD---HENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRSNQ--AL 239 T+RE+ LLR ++ H N+V + D+ A+ V + +E +D DL + L Sbjct: 53 TVREVALLRRLEAFEHPNVVRLMDVCATARTDRETKVTLVFEHVDQDLRTYLDKAPPPGL 112 Query: 240 SEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTSETDFMT 419 E + + Q LRGL ++H+ ++HRDLKP N+L+ + +K+ DFGLAR S +T Sbjct: 113 PVETIKDLMRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALT 172 Query: 420 EYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIG 599 VVT WYRAPE+LL S+ Y +D+WSVGCIF E+ RKPLF G QL + +LIG Sbjct: 173 PVVVTLWYRAPEVLLQST-YATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIG 231 Query: 600 TPNEAD 617 P E D Sbjct: 232 LPPEDD 237
>KSG7_ARATH (Q39011) Shaggy-related protein kinase eta (EC 2.7.11.1) (ASK-eta)| (BRASSINOSTEROID-INSENSITIVE 2) (ULTRACURVATA1) Length = 380 Score = 140 bits (352), Expect = 4e-33 Identities = 73/198 (36%), Positives = 125/198 (63%), Gaps = 8/198 (4%) Frame = +3 Query: 63 DAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYI--AYELMDTDLHQIIR---- 224 D + RE++L+R MDH N+V ++ T+ +++++ E + L+++++ Sbjct: 74 DRRYKNRELQLMRVMDHPNVVCLKHCF--FSTTSKDELFLNLVMEYVPESLYRVLKHYSS 131 Query: 225 SNQALSEEHCQYFLYQILRGLKYIHS-ANVLHRDLKPSNLLLNA-NCDLKICDFGLARTT 398 +NQ + + + ++YQI RGL YIH+ A V HRDLKP NLL++ +KICDFG A+ Sbjct: 132 ANQRMPLVYVKLYMYQIFRGLAYIHNVAGVCHRDLKPQNLLVDPLTHQVKICDFGSAKQL 191 Query: 399 SETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLR 578 + + Y+ +R+YRAPEL+ ++EYT +ID+WS GC+ EL+ +PLFPG + V QL Sbjct: 192 VKGEANISYICSRFYRAPELIFGATEYTTSIDIWSAGCVLAELLLGQPLFPGENAVDQLV 251 Query: 579 LLMELIGTPNEADLDFVN 632 +++++GTP ++ +N Sbjct: 252 EIIKVLGTPTREEIRCMN 269
>BUR1_EMENI (Q96VK3) Serine/threonine-protein kinase bur1 (EC 2.7.11.22) (EC| 2.7.11.23) (Pitalre-like kinase A) Length = 544 Score = 140 bits (352), Expect = 4e-33 Identities = 76/198 (38%), Positives = 115/198 (58%), Gaps = 17/198 (8%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFN---DVYIAYELMDTDLHQIIRSNQA-LSE 245 LREIKLL+ + H NI+ +R++ + +Y+ + M+ DL ++ + + SE Sbjct: 70 LREIKLLKMLSHTNIMQLREMAVERSKGEGRKKPSMYMVFPYMEHDLSGLLENPEVHFSE 129 Query: 246 EHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTSET------ 407 + ++ Q+L GLKY+H +LHRD+K +NLL++ L+I DFGLAR E Sbjct: 130 AQIKCYMIQLLEGLKYLHGNCILHRDMKAANLLISNQGILQIADFGLARPFDEAPPQPGK 189 Query: 408 -------DFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHV 566 D+ T VVTRWYR PELLL YT+AID+W VGC+F E+ KP+ G + Sbjct: 190 GAGEAKRDYTT-LVVTRWYRPPELLLQLRRYTSAIDMWGVGCVFGEMFKGKPILAGNSDL 248 Query: 567 HQLRLLMELIGTPNEADL 620 +Q +L+ L+GTP E ++ Sbjct: 249 NQAQLIFSLVGTPTEENM 266
>CDK10_HUMAN (Q15131) Cell division protein kinase 10 (EC 2.7.11.22)| (Serine/threonine-protein kinase PISSLRE) Length = 360 Score = 139 bits (351), Expect = 5e-33 Identities = 73/181 (40%), Positives = 110/181 (60%), Gaps = 2/181 (1%) Frame = +3 Query: 75 TLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRSNQA-LSEEH 251 +LREI LL + H NIV +++++ +++ + DL ++ + SE Sbjct: 83 SLREITLLLRLRHPNIVELKEVVVGNH---LESIFLVMGYCEQDLASLLENMPTPFSEAQ 139 Query: 252 CQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEYV 428 + + Q+LRGL+Y+H ++HRDLK SNLL+ +K DFGLAR MT V Sbjct: 140 VKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKV 199 Query: 429 VTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPN 608 VT WYRAPELLL ++ T +ID+W+VGCI EL+ +PL PG +HQ+ L+++L+GTP+ Sbjct: 200 VTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPS 259 Query: 609 E 611 E Sbjct: 260 E 260
>KSG4_ARATH (Q9FVS6) Shaggy-related protein kinase delta (EC 2.7.11.1)| (ASK-delta) Length = 420 Score = 139 bits (351), Expect = 5e-33 Identities = 73/200 (36%), Positives = 118/200 (59%), Gaps = 8/200 (4%) Frame = +3 Query: 63 DAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAY------ELMDTDLHQIIR 224 D + RE+++++ +DH N+V ++ RT +VY+ E ++ R Sbjct: 116 DKRYKNRELQIMQMLDHPNVVCLKHSF--YSRTENEEVYLNLVLEFVPETVNRTARSYSR 173 Query: 225 SNQALSEEHCQYFLYQILRGLKYIHSA-NVLHRDLKPSNLLLNANC-DLKICDFGLARTT 398 NQ + + + + YQI RGL Y+H+ + HRD+KP NLL+N + LKICDFG A+ Sbjct: 174 MNQLMPLIYVKLYTYQICRGLAYLHNCCGLCHRDIKPQNLLVNPHTHQLKICDFGSAKVL 233 Query: 399 SETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLR 578 + + Y+ +R+YRAPEL+ ++EYT AID+WS GC+ EL+ +PLFPG V QL Sbjct: 234 VKGEPNISYICSRYYRAPELIFGATEYTTAIDIWSTGCVMAELLLGQPLFPGESGVDQLV 293 Query: 579 LLMELIGTPNEADLDFVNEN 638 +++++GTP ++ +N N Sbjct: 294 EIIKVLGTPTREEIKCMNPN 313
>CDK2_ENTHI (Q04770) Cell division protein kinase 2 homolog (EC 2.7.11.22)| Length = 291 Score = 139 bits (350), Expect = 7e-33 Identities = 72/180 (40%), Positives = 110/180 (61%), Gaps = 1/180 (0%) Frame = +3 Query: 75 TLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRSNQALSEEHC 254 ++REI +L + H N+V + DI + +Y+ +E D DL+Q + + + Sbjct: 48 SVREIAVLLELKHPNVVDLYDIYLEDKF-----LYLVFEFCDEDLYQFMSRSSKIPINET 102 Query: 255 QYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTSETD-FMTEYVV 431 + +YQIL+GL + H +LHRD+KP N+L+N N +K+ +FGLAR T+ D T VV Sbjct: 103 RSIVYQILQGLAFCHYHQILHRDMKPQNILINKNGTIKLGEFGLARLTTINDRKYTSEVV 162 Query: 432 TRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPNE 611 T WYRAPE+LL +++Y AID+WS IF EL++++ LF GR + QL + +GTP E Sbjct: 163 TLWYRAPEILLGATQYGGAIDIWSTAAIFGELINKEELFKGRCKIDQLFKIFSQLGTPTE 222
>BUR1_YARLI (Q6C842) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 706 Score = 139 bits (350), Expect = 7e-33 Identities = 73/193 (37%), Positives = 110/193 (56%), Gaps = 15/193 (7%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFND---VYIAYELMDTDLHQIIRSNQA-LSE 245 LREI++L+ + HEN++ + D+ + + VY+ MD DL ++ + LS Sbjct: 83 LREIRILKLLRHENVIPLVDLAVERGDQSKKERGCVYMVTPYMDHDLAGLLGNQSVQLSP 142 Query: 246 EHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-------- 401 H + ++ Q+L G+ Y+H+ LHRD+K +N+L+N LK+ DFGLAR Sbjct: 143 AHIKCYMLQLLEGIGYLHAKKFLHRDIKAANILVNDQGILKLADFGLARGYDGPAPNSQT 202 Query: 402 ---ETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQ 572 T+ +T VVTRWYR PEL+L +YT AID+W +GC+F E RKP+FPG V Q Sbjct: 203 AGVNTENLTAMVVTRWYRPPELILGDRKYTTAIDMWGIGCVFGEFFTRKPIFPGASDVDQ 262 Query: 573 LRLLMELIGTPNE 611 + + +G P E Sbjct: 263 GSKIFQAVGVPTE 275
>MSK1_MEDSA (P51137) Glycogen synthase kinase-3 homolog MsK-1 (EC 2.7.11.1)| Length = 411 Score = 139 bits (350), Expect = 7e-33 Identities = 74/200 (37%), Positives = 121/200 (60%), Gaps = 8/200 (4%) Frame = +3 Query: 63 DAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYI--AYELMDTDLHQIIRS--- 227 D + RE++ +R +DH N+V+++ T +++Y+ E + +H++I+ Sbjct: 109 DKRYKNRELQTMRLLDHPNVVSLKHCF--FSTTEKDELYLNLVLEYVPETVHRVIKHYSK 166 Query: 228 -NQALSEEHCQYFLYQILRGLKYIHSA-NVLHRDLKPSNLLLNANC-DLKICDFGLARTT 398 NQ + + + + YQI R L YIH V HRD+KP NLL+N + +K+CDFG A+ Sbjct: 167 LNQRMPMIYVKLYTYQIFRALSYIHRCIGVCHRDIKPQNLLVNPHTHQVKLCDFGSAKVL 226 Query: 399 SETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLR 578 + + Y+ +R+YRAPEL+ ++EYT AIDVWSVGC+ EL+ +PLFPG V QL Sbjct: 227 VKGEPNISYICSRYYRAPELIFGATEYTTAIDVWSVGCVLAELLLGQPLFPGERGVDQLV 286 Query: 579 LLMELIGTPNEADLDFVNEN 638 +++++GTP ++ +N N Sbjct: 287 EIIKVLGTPTREEIKCMNPN 306
>CDC2_ORYLU (Q9DG98) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 139 bits (349), Expect = 9e-33 Identities = 75/181 (41%), Positives = 104/181 (57%), Gaps = 4/181 (2%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQI---IRSNQALSEE 248 +RE+ LL+ + H N+V + D++ R +Y+ +E + DL + I S Q + Sbjct: 49 VREVSLLQELKHPNVVRLLDVLMQESR-----LYLIFEFLSMDLKKYLDSIPSGQYMDPM 103 Query: 249 HCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEY 425 + +LYQIL G+ + H VLHRDLKP NLL++ +K+ DFGLAR T Sbjct: 104 LVKSYLYQILEGIYFCHRRRVLHRDLKPQNLLIDNKGVIKLADFGLARAFGVPVRVYTHE 163 Query: 426 VVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTP 605 VVT WYRAPE+LL S Y+ +DVWS G IF EL +KPLF G + QL + +GTP Sbjct: 164 VVTLWYRAPEVLLGSPRYSTPVDVWSTGTIFAELATKKPLFHGDSEIDQLFRIFRTLGTP 223 Query: 606 N 608 N Sbjct: 224 N 224
>CDC2_ORYLA (Q9DGD3) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 139 bits (349), Expect = 9e-33 Identities = 75/181 (41%), Positives = 104/181 (57%), Gaps = 4/181 (2%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQI---IRSNQALSEE 248 +RE+ LL+ + H N+V + D++ R +Y+ +E + DL + I S Q + Sbjct: 49 VREVSLLQELKHPNVVRLLDVLMQESR-----LYLIFEFLSMDLKKYLDSIPSGQYMDPM 103 Query: 249 HCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEY 425 + +LYQIL G+ + H VLHRDLKP NLL++ +K+ DFGLAR T Sbjct: 104 LVKSYLYQILEGIYFCHRRRVLHRDLKPQNLLIDNKGVIKLADFGLARAFGVPVRVYTHE 163 Query: 426 VVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTP 605 VVT WYRAPE+LL S Y+ +DVWS G IF EL +KPLF G + QL + +GTP Sbjct: 164 VVTLWYRAPEVLLGSPRYSTPVDVWSTGTIFAELATKKPLFHGDSEIDQLFRIFRTLGTP 223 Query: 606 N 608 N Sbjct: 224 N 224
>CDC2_ORYJA (Q9DGA2) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 139 bits (349), Expect = 9e-33 Identities = 75/181 (41%), Positives = 104/181 (57%), Gaps = 4/181 (2%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQI---IRSNQALSEE 248 +RE+ LL+ + H N+V + D++ R +Y+ +E + DL + I S Q + Sbjct: 49 VREVSLLQELKHPNVVRLLDVLMQESR-----LYLIFEFLSMDLKKYLDSIPSGQYMDPM 103 Query: 249 HCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEY 425 + +LYQIL G+ + H VLHRDLKP NLL++ +K+ DFGLAR T Sbjct: 104 LVKSYLYQILEGIYFCHRRRVLHRDLKPQNLLIDNKGVIKLADFGLARAFGVPVRVYTHE 163 Query: 426 VVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTP 605 VVT WYRAPE+LL S Y+ +DVWS G IF EL +KPLF G + QL + +GTP Sbjct: 164 VVTLWYRAPEVLLGSPRYSTPVDVWSTGTIFAELATKKPLFHGDSEIDQLFRIFRTLGTP 223 Query: 606 N 608 N Sbjct: 224 N 224
>CC2H3_TRYBB (P54666) Cell division control protein 2 homolog 3 (EC 2.7.11.22)| Length = 311 Score = 139 bits (349), Expect = 9e-33 Identities = 73/182 (40%), Positives = 109/182 (59%), Gaps = 2/182 (1%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQII-RSNQALSEEHC 254 LRE+ +L+ + H NIV + D+I A +Y+ +E +D DL + + + A + Sbjct: 68 LREVSILQEIHHPNIVNLLDVI-----CADGKLYLIFEYVDHDLKKALEKRGGAFTGTTL 122 Query: 255 QYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEYVV 431 + +YQ+L GL + H ++HRDLKP+N+L+ + +KI DFGLAR T VV Sbjct: 123 KKIIYQLLEGLSFCHRHRIVHRDLKPANILVTTDNSVKIADFGLARAFQIPMHTYTHEVV 182 Query: 432 TRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPNE 611 T WYRAPE+LL YT A+D+WS+GCIF EL K LF G + QL + +++GTP + Sbjct: 183 TLWYRAPEILLGEKHYTPAVDMWSIGCIFAELARGKVLFRGDSEIGQLFEIFQVLGTPMD 242 Query: 612 AD 617 A+ Sbjct: 243 AE 244
>BUR1_DEBHA (Q6BV06) Serine/threonine-protein kinase BUR1 (EC 2.7.11.22) (EC| 2.7.11.23) Length = 608 Score = 139 bits (349), Expect = 9e-33 Identities = 81/201 (40%), Positives = 113/201 (56%), Gaps = 24/201 (11%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPA-----------QRTAFNDVYIAYELMDTDLHQIIR 224 +REI +L+ ++H+NI+ I D+I QR F Y M +DL ++ Sbjct: 84 MREITILKKLNHKNILKIIDMIYEEPKISNPQDILHQRGCF---YTVSPYMCSDLVGLLE 140 Query: 225 S-NQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTT- 398 + N L H + F+ Q+L G++YIH LHRD+K +N+L++ N LKI DFGLAR Sbjct: 141 NPNINLEVSHIKCFMEQLLHGIQYIHEQMFLHRDIKAANILIDRNGTLKIADFGLARVYH 200 Query: 399 -SETDFM----------TEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPL 545 S FM T VVTRWYR PELLL YT A+D+W +GC+F EL RKP+ Sbjct: 201 GSPPKFMSGPGGGERAYTGLVVTRWYRPPELLLGERRYTTAVDMWGIGCVFGELFTRKPI 260 Query: 546 FPGRDHVHQLRLLMELIGTPN 608 G+ HQ +L+ +L+G PN Sbjct: 261 LVGKTDSHQAQLIFDLVGPPN 281
>KSG3_ARATH (P43289) Shaggy-related protein kinase gamma (EC 2.7.11.1)| (ASK-gamma) Length = 409 Score = 138 bits (348), Expect = 1e-32 Identities = 73/200 (36%), Positives = 120/200 (60%), Gaps = 8/200 (4%) Frame = +3 Query: 63 DAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYI--AYELMDTDLHQIIRS--- 227 D + RE++ +R +DH N+V+++ T +++Y+ E + +H++I+ Sbjct: 107 DRRYKNRELQTMRLLDHPNVVSLKHCF--FSTTEKDELYLNLVLEYVPETVHRVIKHYNK 164 Query: 228 -NQALSEEHCQYFLYQILRGLKYIHSA-NVLHRDLKPSNLLLNANC-DLKICDFGLARTT 398 NQ + + + + YQI R L YIH V HRD+KP NLL+N + +K+CDFG A+ Sbjct: 165 LNQRMPLVYVKLYTYQIFRSLSYIHRCIGVCHRDIKPQNLLVNPHTHQVKLCDFGSAKVL 224 Query: 399 SETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLR 578 + + Y+ +R+YRAPEL+ ++EYT AIDVWS GC+ EL+ +PLFPG V QL Sbjct: 225 VKGEPNISYICSRYYRAPELIFGATEYTTAIDVWSAGCVLAELLLGQPLFPGESGVDQLV 284 Query: 579 LLMELIGTPNEADLDFVNEN 638 +++++GTP ++ +N N Sbjct: 285 EIIKVLGTPTREEIKCMNPN 304
>CDK4_XENLA (Q91727) Cell division protein kinase 4 (EC 2.7.11.22)| (Cyclin-dependent kinase 4) Length = 319 Score = 138 bits (348), Expect = 1e-32 Identities = 76/186 (40%), Positives = 108/186 (58%), Gaps = 5/186 (2%) Frame = +3 Query: 75 TLREIKLLR---HMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRS--NQAL 239 T+RE+ LL+ H DH NIV + D+ A+ V + +E +D DL + L Sbjct: 53 TVREVTLLKRLEHFDHPNIVKLMDVCASARTDRETKVTLVFEHVDQDLKTYLSKVPPPGL 112 Query: 240 SEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTSETDFMT 419 E + + Q L GL+++H ++HRDLKP N+L+ + +K+ DFGLAR S +T Sbjct: 113 PLETIKDLMKQFLSGLEFLHLNCIVHRDLKPENILVTSGGQVKLADFGLARIYSCQMALT 172 Query: 420 EYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIG 599 VVT WYRAPE+LL S+ Y +DVWS GCIF E+ RKPLF G QL + ++IG Sbjct: 173 PVVVTLWYRAPEVLLQST-YATPVDVWSAGCIFAEMFKRKPLFCGNSEADQLCKIFDIIG 231 Query: 600 TPNEAD 617 P+E + Sbjct: 232 LPSEEE 237
>MSK2_MEDSA (P51138) Glycogen synthase kinase-3 homolog MsK-2 (EC 2.7.11.1)| Length = 411 Score = 138 bits (348), Expect = 1e-32 Identities = 74/200 (37%), Positives = 121/200 (60%), Gaps = 8/200 (4%) Frame = +3 Query: 63 DAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYI--AYELMDTDLHQIIRS--- 227 D + RE++ +R +DH N+V ++ T +++Y+ E + +H++IR Sbjct: 108 DKRYKNRELQTMRLLDHPNVVTLKHCF--FSTTEKDELYLNLVLEFVPETVHRVIRHYSK 165 Query: 228 -NQALSEEHCQYFLYQILRGLKYIHSA-NVLHRDLKPSNLLLNANC-DLKICDFGLARTT 398 NQ + + + + YQI R L YIH+ V HRD+KP NLL+N + LK+CDFG A+ Sbjct: 166 MNQRMPLIYVKLYSYQICRSLAYIHNCVGVSHRDIKPQNLLVNPHTHQLKLCDFGSAKVL 225 Query: 399 SETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLR 578 + + Y+ +R+YRAPEL+ ++EYT+AID+WS GC+ EL+ +PLFPG V QL Sbjct: 226 VKGEPNISYICSRYYRAPELIFGATEYTSAIDIWSAGCVLGELLLGQPLFPGASGVDQLV 285 Query: 579 LLMELIGTPNEADLDFVNEN 638 +++++GTP ++ +N N Sbjct: 286 EIIKVLGTPTREEIKCMNPN 305
>KSG1_ARATH (P43288) Shaggy-related protein kinase alpha (EC 2.7.11.1)| (ASK-alpha) Length = 405 Score = 138 bits (347), Expect = 2e-32 Identities = 73/200 (36%), Positives = 120/200 (60%), Gaps = 8/200 (4%) Frame = +3 Query: 63 DAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYI--AYELMDTDLHQIIRS--- 227 D + RE++ +R +DH N+V+++ T +++Y+ E + +H++I+ Sbjct: 103 DRRYKNRELQTMRLLDHPNVVSLKHCF--FSTTEKDELYLNLVLEYVPETVHRVIKHYNK 160 Query: 228 -NQALSEEHCQYFLYQILRGLKYIHSA-NVLHRDLKPSNLLLNANC-DLKICDFGLARTT 398 NQ + + + + YQI R L YIH V HRD+KP NLL+N + +K+CDFG A+ Sbjct: 161 LNQRMPLIYVKLYTYQIFRALSYIHRCIGVCHRDIKPQNLLVNPHTHQVKLCDFGSAKVL 220 Query: 399 SETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLR 578 + + Y+ +R+YRAPEL+ ++EYT AIDVWS GC+ EL+ +PLFPG V QL Sbjct: 221 VKGEPNISYICSRYYRAPELIFGATEYTTAIDVWSAGCVLAELLLGQPLFPGESGVDQLV 280 Query: 579 LLMELIGTPNEADLDFVNEN 638 +++++GTP ++ +N N Sbjct: 281 EIIKVLGTPTREEIKCMNPN 300
>CDK4_HUMAN (P11802) Cell division protein kinase 4 (EC 2.7.11.22)| (Cyclin-dependent kinase 4) (PSK-J3) Length = 303 Score = 138 bits (347), Expect = 2e-32 Identities = 76/186 (40%), Positives = 109/186 (58%), Gaps = 5/186 (2%) Frame = +3 Query: 75 TLREIKLLRHMD---HENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRSNQ--AL 239 T+RE+ LLR ++ H N+V + D+ ++ V + +E +D DL + L Sbjct: 53 TVREVALLRRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGL 112 Query: 240 SEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTSETDFMT 419 E + + Q LRGL ++H+ ++HRDLKP N+L+ + +K+ DFGLAR S +T Sbjct: 113 PAETIKDLMRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALT 172 Query: 420 EYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIG 599 VVT WYRAPE+LL S+ Y +D+WSVGCIF E+ RKPLF G QL + +LIG Sbjct: 173 PVVVTLWYRAPEVLLQST-YATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIG 231 Query: 600 TPNEAD 617 P E D Sbjct: 232 LPPEDD 237
>MOK_HUMAN (Q9UQ07) MAPK/MAK/MRK overlapping kinase (EC 2.7.11.22) (MOK| protein kinase) (Renal tumor antigen 1) (RAGE-1) Length = 419 Score = 137 bits (346), Expect = 2e-32 Identities = 71/200 (35%), Positives = 121/200 (60%), Gaps = 2/200 (1%) Frame = +3 Query: 12 GSRWPSXKIANAFDNKIDAKRTLREIKLLRHMD-HENIVAIRDIIPPAQRTAFNDVYIAY 188 G+ + ++ F++ I+ LREI+ LR ++ H NI+ + +++ + + + Sbjct: 27 GNYYACKQMKQRFES-IEQVNNLREIQALRRLNPHPNILMLHEVVFDRKS---GSLALIC 82 Query: 189 ELMDTDLHQIIRSNQ-ALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDL 365 ELMD +++++IR + LSE+ +++YQ+ + L +IH + HRD+KP N+L+ + L Sbjct: 83 ELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLDHIHRNGIFHRDVKPENILIKQDV-L 141 Query: 366 KICDFGLARTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPL 545 K+ DFG R+ TEY+ TRWYRAPE LL YT +D+WS GC+F E+ +PL Sbjct: 142 KLGDFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGFYTYKMDLWSAGCVFYEIASLQPL 201 Query: 546 FPGRDHVHQLRLLMELIGTP 605 FPG + + Q+ + ++IGTP Sbjct: 202 FPGVNELDQISKIHDVIGTP 221
>CDK4_RAT (P35426) Cell division protein kinase 4 (EC 2.7.11.22)| (Cyclin-dependent kinase 4) (PSK-J3) Length = 303 Score = 137 bits (346), Expect = 2e-32 Identities = 76/186 (40%), Positives = 109/186 (58%), Gaps = 5/186 (2%) Frame = +3 Query: 75 TLREIKLLRHMD---HENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRSNQ--AL 239 T+RE+ LLR ++ H N+V + D+ ++ V + +E +D DL + L Sbjct: 53 TVREVALLRRLEAFEHPNVVRLMDVCATSRTDRDIKVTLVFEHIDQDLRTYLDKAPPPGL 112 Query: 240 SEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTSETDFMT 419 E + + Q L GL ++H+ ++HRDLKP N+L+ +N +K+ DFGLAR S +T Sbjct: 113 PVETIKDLMRQFLSGLDFLHANCIVHRDLKPENILVTSNGTVKLADFGLARIYSYQMALT 172 Query: 420 EYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIG 599 VVT WYRAPE+LL S+ Y +D+WSVGCIF E+ RKPLF G QL + +LIG Sbjct: 173 PVVVTLWYRAPEVLLQST-YATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIG 231 Query: 600 TPNEAD 617 P E D Sbjct: 232 LPPEDD 237
>CDK4_MOUSE (P30285) Cell division protein kinase 4 (EC 2.7.11.22)| (Cyclin-dependent kinase 4) (PSK-J3) (CRK3) Length = 303 Score = 137 bits (346), Expect = 2e-32 Identities = 76/186 (40%), Positives = 109/186 (58%), Gaps = 5/186 (2%) Frame = +3 Query: 75 TLREIKLLRHMD---HENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRSNQ--AL 239 T+RE+ LLR ++ H N+V + D+ ++ V + +E +D DL + L Sbjct: 53 TVREVALLRRLEAFEHPNVVRLMDVCATSRTDRDIKVTLVFEHIDQDLRTYLDKAPPPGL 112 Query: 240 SEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTSETDFMT 419 E + + Q L GL ++H+ ++HRDLKP N+L+ +N +K+ DFGLAR S +T Sbjct: 113 PVETIKDLMRQFLSGLDFLHANCIVHRDLKPENILVTSNGTVKLADFGLARIYSYQMALT 172 Query: 420 EYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIG 599 VVT WYRAPE+LL S+ Y +D+WSVGCIF E+ RKPLF G QL + +LIG Sbjct: 173 PVVVTLWYRAPEVLLQST-YATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIG 231 Query: 600 TPNEAD 617 P E D Sbjct: 232 LPPEDD 237
>CDC2_ORYCU (Q9DGA5) Cell division control protein 2 homolog (EC 2.7.11.22) (EC| 2.7.11.23) (p34 protein kinase) (Cyclin-dependent kinase 1) (CDK1) Length = 303 Score = 137 bits (346), Expect = 2e-32 Identities = 74/181 (40%), Positives = 104/181 (57%), Gaps = 4/181 (2%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQI---IRSNQALSEE 248 +RE+ LL+ + H N+V + D++ R +Y+ +E + DL + I S Q + Sbjct: 49 VREVSLLQELKHPNVVRLLDVLMQESR-----LYLIFEFLSMDLKKYLDSIPSGQYMDPM 103 Query: 249 HCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEY 425 + +LYQIL G+ + H VLHRDLKP NLL++ +K+ DFGL+R T Sbjct: 104 LVKSYLYQILEGIYFCHRRRVLHRDLKPQNLLIDNKGVIKLADFGLSRAFGVPVRVYTHE 163 Query: 426 VVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTP 605 VVT WYRAPE+LL S Y+ +DVWS G IF EL +KPLF G + QL + +GTP Sbjct: 164 VVTLWYRAPEVLLGSPRYSTPVDVWSTGTIFAELATKKPLFHGDSEIDQLFRIFRTLGTP 223 Query: 606 N 608 N Sbjct: 224 N 224
>GSK3_SCHPO (Q10452) Protein kinase gsk3 (EC 2.7.11.1) (Protein kinaae skp1)| Length = 387 Score = 137 bits (346), Expect = 2e-32 Identities = 82/212 (38%), Positives = 124/212 (58%), Gaps = 16/212 (7%) Frame = +3 Query: 51 DNKIDAKRTL-------REIKLLRHMDHENIVAIRDIIPPAQRTAFN--DVYI--AYELM 197 D+K KR L RE++++R M H NIV D+I T N +VY+ E M Sbjct: 55 DSKAAIKRVLQDKRFKNRELQIMRIMKHPNIV---DLIAYYYTTGDNSDEVYLNLVLEFM 111 Query: 198 DTDLHQIIR--SNQALSEE--HCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNA-NCD 362 +++ R + Q LS + ++YQ+LR L YIH++ + HRD+KP NLLL+ N Sbjct: 112 PETIYRASRLYTRQKLSMPMLEVKLYIYQLLRSLAYIHASGICHRDIKPQNLLLDPENGI 171 Query: 363 LKICDFGLARTTSETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKP 542 LK+CDFG A+ + Y+ +R+YRAPEL+ +++YT AID+WS GC+ ELM P Sbjct: 172 LKLCDFGSAKILVAGEPNVSYICSRYYRAPELIFGATDYTHAIDIWSTGCVMAELMLGHP 231 Query: 543 LFPGRDHVHQLRLLMELIGTPNEADLDFVNEN 638 LFPG + QL +++++GTP+ + +N N Sbjct: 232 LFPGESGIDQLVEIIKILGTPSREQIKTMNPN 263
>CC2H1_TRYCO (P54664) Cell division control protein 2 homolog 1 (EC 2.7.11.22)| Length = 301 Score = 137 bits (346), Expect = 2e-32 Identities = 71/179 (39%), Positives = 108/179 (60%), Gaps = 2/179 (1%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQII-RSNQALSEEHC 254 +REI +L+ + HENIV + D+ R + + +E M+ DL + + R++ L Sbjct: 50 IREISILKELRHENIVRLLDVCHSENR-----LNLVFEYMEMDLKKYMDRASGNLDPATI 104 Query: 255 QYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTS-ETDFMTEYVV 431 Q F+ +L+G+++ H NVLHRDLKP NLL++ +LK+ DFGL R T VV Sbjct: 105 QEFMRSLLKGVRFCHERNVLHRDLKPPNLLISREKELKLADFGLGRAFGIPVKKYTHEVV 164 Query: 432 TRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPN 608 T WYR+P++LL S++Y +D+WSVGCIF E+ PLF G++ QL + +GTP+ Sbjct: 165 TLWYRSPDVLLGSTQYGTPVDIWSVGCIFAEMAIGAPLFAGKNDADQLLRIFRFLGTPS 223
>CDC2_AJECA (P54119) Cell division control protein 2 (EC 2.7.11.22) (EC| 2.7.11.23) (Cyclin-dependent protein kinase) Length = 324 Score = 137 bits (346), Expect = 2e-32 Identities = 75/200 (37%), Positives = 111/200 (55%), Gaps = 22/200 (11%) Frame = +3 Query: 78 LREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRS---------- 227 +REI LL+ M NIV + +I+ + +Y+ +E +D DL + + + Sbjct: 50 IREISLLKEMHDPNIVRLLNIV----HADGHKLYLVFEFLDLDLKKYMEALPVSEGGRGK 105 Query: 228 -----------NQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKIC 374 L E + F+ Q++ G++Y HS VLHRDLKP NLL++ +LK+ Sbjct: 106 ALPDGSTLDMNRLGLGEAMVKKFMAQLVEGIRYCHSHRVLHRDLKPQNLLIDREGNLKLA 165 Query: 375 DFGLARTTS-ETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFP 551 DFGLAR T VVT WYRAPE+LL +Y+ +D+WSVG IF E+ RKPLFP Sbjct: 166 DFGLARAFGVPLRTYTHEVVTLWYRAPEILLGGRQYSTGVDMWSVGAIFAEMCTRKPLFP 225 Query: 552 GRDHVHQLRLLMELIGTPNE 611 G + ++ + +L+GTP+E Sbjct: 226 GDSEIDEIFKIFKLLGTPDE 245
>MOK_MOUSE (Q9WVS4) MAPK/MAK/MRK overlapping kinase (EC 2.7.11.22) (MOK| protein kinase) Length = 420 Score = 137 bits (345), Expect = 3e-32 Identities = 70/189 (37%), Positives = 116/189 (61%), Gaps = 2/189 (1%) Frame = +3 Query: 60 IDAKRTLREIKLLRHMD-HENIVAIRDIIPPAQRTAFNDVYIAYELMDTDLHQIIRSNQ- 233 I+ +LREI+ LR ++ H NI+A+ +++ + + + ELMD +++++IR + Sbjct: 42 IEQVNSLREIQALRRLNPHPNILALHEVVFDRKS---GSLALICELMDMNIYELIRGRRH 98 Query: 234 ALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTSETDF 413 LSE+ ++YQ+ + L ++H + HRD+KP N+L+ + LK+ DFG R+ Sbjct: 99 PLSEKKIMLYMYQLCKSLDHMHRNGIFHRDVKPENILVKQDV-LKLGDFGSCRSVYSKQP 157 Query: 414 MTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMEL 593 TEY+ TRWYRAPE LL YT +D+WS GC+F E+ +PLFPG + + Q+ + ++ Sbjct: 158 YTEYISTRWYRAPECLLTDGFYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDV 217 Query: 594 IGTPNEADL 620 IGTP + L Sbjct: 218 IGTPCQKTL 226
>MSK3_MEDSA (P51139) Glycogen synthase kinase-3 homolog MsK-3 (EC 2.7.11.1)| Length = 411 Score = 137 bits (345), Expect = 3e-32 Identities = 75/200 (37%), Positives = 120/200 (60%), Gaps = 8/200 (4%) Frame = +3 Query: 63 DAKRTLREIKLLRHMDHENIVAIRDIIPPAQRTAFNDVYI--AYELMDTDLHQIIRS--- 227 D + RE++ +R +DH N+V+++ T +++Y+ E + + ++IR Sbjct: 108 DKRYKNRELQTMRLLDHPNVVSLKHCF--FSTTEKDELYLNLVLEYVPETVSRVIRHYNK 165 Query: 228 -NQALSEEHCQYFLYQILRGLKYIH-SANVLHRDLKPSNLLLNANC-DLKICDFGLARTT 398 NQ + + + + YQI R L YIH S V HRD+KP NLL+N + LKICDFG A+ Sbjct: 166 MNQRMPMIYVKLYSYQICRALAYIHNSIGVCHRDIKPQNLLVNPHTHQLKICDFGSAKVL 225 Query: 399 SETDFMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLR 578 + + Y+ +R+YRAPEL+ ++EYT AID+WS GC+ EL+ +PLFPG V QL Sbjct: 226 VKGEPNISYICSRYYRAPELIFGATEYTTAIDIWSAGCVLGELLLGQPLFPGESGVDQLV 285 Query: 579 LLMELIGTPNEADLDFVNEN 638 +++++GTP ++ +N N Sbjct: 286 EIIKVLGTPTREEIKCMNPN 305 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 91,057,776 Number of Sequences: 219361 Number of extensions: 1901434 Number of successful extensions: 8824 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 6764 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 7073 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 6029593548 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
