ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bags33j20 |
|---|---|
| Clone Library Name | barley_pub |
>ERG3_ORYSA (Q7F9X0) Elicitor-responsive protein 3 (16 kDa phloem protein)| (RPP16) Length = 144 Score = 243 bits (621), Expect = 2e-64 Identities = 115/144 (79%), Positives = 129/144 (89%) Frame = +2 Query: 95 MAQGTLEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKSTVASGKGSDPEWNETFVFTV 274 M QGTLEVLLVGAKGLENTDYLCNMDPYAVL+C SQEQKS+VASGKGSDPEWNETF+F+V Sbjct: 1 MVQGTLEVLLVGAKGLENTDYLCNMDPYAVLKCRSQEQKSSVASGKGSDPEWNETFMFSV 60 Query: 275 SENARELVIKLLDSDGGTEDDSVGEATIPLDGVYTEGSIPPTVYNVVKDEEYRGEIKIGL 454 + NA EL+IKL+DSD GT+DD VGEATI L+ +YTEGSIPPTVYNVVK+EEYRGEIK+GL Sbjct: 61 THNATELIIKLMDSDSGTDDDFVGEATISLEAIYTEGSIPPTVYNVVKEEEYRGEIKVGL 120 Query: 455 TFTPEEARDEDQPEENYGGWNQSS 526 TFTPE+ RD EE+ GGW QSS Sbjct: 121 TFTPEDDRDRGLSEEDIGGWKQSS 144
>Y1322_ARATH (Q9C8S6) C2 domain protein At1g63220| Length = 147 Score = 194 bits (493), Expect = 2e-49 Identities = 92/143 (64%), Positives = 107/143 (74%) Frame = +2 Query: 95 MAQGTLEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKSTVASGKGSDPEWNETFVFTV 274 M GTLEV+LV AKGLE+ D+L NMDPY L C +Q+QKS VA G G+ PEWNETF+FTV Sbjct: 1 MPHGTLEVVLVSAKGLEDADFLNNMDPYVQLTCRTQDQKSNVAEGMGTTPEWNETFIFTV 60 Query: 275 SENARELVIKLLDSDGGTEDDSVGEATIPLDGVYTEGSIPPTVYNVVKDEEYRGEIKIGL 454 SE EL K+ D D GTEDD+VGEATIPL+ V+ EGSIPPT YNVVKDEEY+GEI + L Sbjct: 61 SEGTTELKAKIFDKDVGTEDDAVGEATIPLEPVFVEGSIPPTAYNVVKDEEYKGEIWVAL 120 Query: 455 TFTPEEARDEDQPEENYGGWNQS 523 +F P E R EE+YGGW S Sbjct: 121 SFKPSENRSRGMDEESYGGWKNS 143
>ERG1_ORYSA (Q7GC09) Elicitor-responsive protein 1 (Fungal elicitor immediate| early-responsive gene 1 protein) (FIERG1) (17 kDa phloem protein) (RPP17) Length = 159 Score = 95.5 bits (236), Expect = 1e-19 Identities = 61/154 (39%), Positives = 89/154 (57%), Gaps = 14/154 (9%) Frame = +2 Query: 104 GTLEVLLVGAKGLENTDYLCNM---DPYAVLRCTSQEQKSTVASGKGSDPEWNETFVFTV 274 G LEV LV AKGL D+L + DPY V++ SQE+KS+VA +G +P WNE F F + Sbjct: 5 GVLEVHLVDAKGLTGNDFLGEIGKIDPYVVVQYRSQERKSSVARDQGKNPSWNEVFKFQI 64 Query: 275 SENA----RELVIKLLDSDGGTEDDSVGEATIPLDGVYTEG------SIPPTVYNVV-KD 421 + A +L ++L+D D + DD +GEATI + + + G + + + VV D Sbjct: 65 NSTAATGQHKLFLRLMDHDTFSRDDFLGEATINVTDLISLGMEHGTWEMSESKHRVVLAD 124 Query: 422 EEYRGEIKIGLTFTPEEARDEDQPEENYGGWNQS 523 + Y GEI++ LTFT A+ +D E+ GGW S Sbjct: 125 KTYHGEIRVSLTFT-ASAKAQDHAEQ-VGGWAHS 156
>PP16B_CUCMA (Q9ZT46) 16 kDa phloem protein 2| Length = 137 Score = 74.7 bits (182), Expect = 2e-13 Identities = 47/131 (35%), Positives = 69/131 (52%), Gaps = 12/131 (9%) Frame = +2 Query: 104 GTLEVLLVGAKGLENTDYLCN-MDPYAVLRCTSQEQKSTVASGKGSDPEWNETFVFTV-- 274 G +EV L+ KGL+ D L +DPYA + QE+ S VA G DP WNE F F V Sbjct: 3 GMMEVHLISGKGLQAHDPLNKPIDPYAEINFKGQERMSKVAKNAGPDPIWNEKFKFLVEY 62 Query: 275 --SENARELVIKLLDSDGGTEDDSVGEATIPLDGVYTEG------SIPPTVYNVVKDEEY 430 S ++ K++D D DD +G+ I + + EG +PP +Y V+ + Y Sbjct: 63 PGSGGDFHILFKVMDHDAIDGDDYIGDVKIDVQNLLAEGVRKGWSELPPRMYQVLAHKIY 122 Query: 431 -RGEIKIGLTF 460 +GEI++G+ F Sbjct: 123 FKGEIEVGVFF 133
>PP16A_CUCMA (Q9ZT47) 16 kDa phloem protein 1| Length = 149 Score = 69.7 bits (169), Expect = 6e-12 Identities = 43/131 (32%), Positives = 70/131 (53%), Gaps = 12/131 (9%) Frame = +2 Query: 104 GTLEVLLVGAKGLENTDYLCN-MDPYAVLRCTSQEQKSTVASGKGSDPEWNETFVFTV-- 274 G +EV L+ KGL+ D L +DPYA + QE+ S VA G +P W+E F F Sbjct: 3 GMMEVHLISGKGLQAHDPLNKPIDPYAEINFKGQERMSKVAKNAGPNPLWDEKFKFLAEY 62 Query: 275 --SENARELVIKLLDSDGGTEDDSVGEATIPLDGVYTEG------SIPPTVYNVVKDE-E 427 S ++ K++D D DD +G+ I + + EG +PP +Y+V+ + Sbjct: 63 PGSGGDFHILFKVMDHDAIDGDDYIGDVKIDVKNLLAEGVRKGKSEMPPRMYHVLAHKIH 122 Query: 428 YRGEIKIGLTF 460 ++GEI++G++F Sbjct: 123 FKGEIEVGVSF 133
>NEDD4_RAT (Q62940) E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-)| Length = 887 Score = 53.1 bits (126), Expect = 6e-07 Identities = 41/153 (26%), Positives = 68/153 (44%), Gaps = 18/153 (11%) Frame = +2 Query: 110 LEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKSTVASG-------KGSDPEWNETFVF 268 + V ++ GL D L DPY +R T + S V + K +P+WNE +F Sbjct: 77 VRVKVIAGIGLAKKDILGASDPY--VRVTLYDPMSGVLTSVQTKTIKKSLNPKWNEEILF 134 Query: 269 TVSENARELVIKLLDSDGGTEDDSVGEATIPLDGVYTEG---SIPPTVYNVV-----KDE 424 V ++ ++ D + T DD +G+ +PL + TE P T + V Sbjct: 135 RVLPQQHRILFEVFDENRLTRDDFLGQVDVPLYPLPTENPRMERPYTFKDFVLHPRSHKS 194 Query: 425 EYRGEIKIGLTFTPEEARDE---DQPEENYGGW 514 +G +++ +T+ P+ D+ DQ EE GW Sbjct: 195 RVKGYLRLKMTYLPKNGSDDENADQAEELEPGW 227
>NEDD4_MOUSE (P46935) E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural| precursor cell expressed developmentally down-regulated protein 4) Length = 887 Score = 51.2 bits (121), Expect = 2e-06 Identities = 40/153 (26%), Positives = 68/153 (44%), Gaps = 18/153 (11%) Frame = +2 Query: 110 LEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKSTVASG-------KGSDPEWNETFVF 268 + V ++ GL D L DPY +R T + S + + K +P+WNE +F Sbjct: 80 VRVKVIAGIGLAKKDILGASDPY--VRVTLYDPMSGILTSVQTKTIKKSLNPKWNEEILF 137 Query: 269 TVSENARELVIKLLDSDGGTEDDSVGEATIPLDGVYTEG---SIPPTVYNVV-----KDE 424 V ++ ++ D + T DD +G+ +PL + TE P T + V Sbjct: 138 RVLPQRHRILFEVFDENRLTRDDFLGQVDVPLYPLPTENPRMERPYTFKDFVLHPRSHKS 197 Query: 425 EYRGEIKIGLTFTPE---EARDEDQPEENYGGW 514 +G +++ +T+ P+ E + DQ EE GW Sbjct: 198 RVKGYLRLKMTYLPKNGSEDENADQAEELEPGW 230
>NEDD4_HUMAN (P46934) E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-)| Length = 1000 Score = 51.2 bits (121), Expect = 2e-06 Identities = 41/154 (26%), Positives = 68/154 (44%), Gaps = 19/154 (12%) Frame = +2 Query: 110 LEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKSTVASG-------KGSDPEWNETFVF 268 + V ++ GL D L DPY +R T + + V + K +P+WNE +F Sbjct: 121 VRVRVIAGIGLAKKDILGASDPY--VRVTLYDPMNGVLTSVQTKTIKKSLNPKWNEEILF 178 Query: 269 TVSENARELVIKLLDSDGGTEDDSVGEATIPLDGVYTEG---SIPPTVYNVV-----KDE 424 V L+ ++ D + T DD +G+ +PL + TE P T + V Sbjct: 179 RVHPQQHRLLFEVFDENRLTRDDFLGQVDVPLYPLPTENPRLERPYTFKDFVLHPRSHKS 238 Query: 425 EYRGEIKIGLTFTPEEARDED----QPEENYGGW 514 +G +++ +T+ P+ + ED Q EE GW Sbjct: 239 RVKGYLRLKMTYLPKTSGSEDDNAEQAEELEPGW 272
>SYT1_CAEEL (P34693) Synaptotagmin-1 (Synaptotagmin I)| Length = 441 Score = 50.1 bits (118), Expect = 5e-06 Identities = 32/93 (34%), Positives = 48/93 (51%), Gaps = 5/93 (5%) Frame = +2 Query: 101 QGTLEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKS--TVASGKGSDPEWNETFVFTV 274 QG L V ++ A+ L D DPY L +++K T K +P +NETF+F V Sbjct: 173 QGQLTVTVIQAEDLPGMDMSGTSDPYVKLYLLPEKKKKVETKVHRKTLNPVFNETFIFKV 232 Query: 275 SEN---ARELVIKLLDSDGGTEDDSVGEATIPL 364 + N A+ LV + D D ++ D +G+ IPL Sbjct: 233 AFNEITAKTLVFAIYDFDRFSKHDQIGQVLIPL 265
>NED4L_HUMAN (Q96PU5) E3 ubiquitin-protein ligase NEDD4-like protein (EC| 6.3.2.-) (Nedd4-2) (NEDD4.2) Length = 975 Score = 47.8 bits (112), Expect = 3e-05 Identities = 37/154 (24%), Positives = 64/154 (41%), Gaps = 19/154 (12%) Frame = +2 Query: 110 LEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKSTVAS------GKGSDPEWNETFVFT 271 L V +V L D DPY L ++ +A K +P+WNE F F Sbjct: 22 LRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQTKTIKKTLNPKWNEEFYFR 81 Query: 272 VSENARELVIKLLDSDGGTEDDSVGEATIPLDGVYTEGSIPPTVYNVVKD---------E 424 V+ + L+ ++ D + T DD +G+ +PL + TE Y KD Sbjct: 82 VNPSNHRLLFEVFDENRLTRDDFLGQVDVPLSHLPTEDPTMERPY-TFKDFLLRPRSHKS 140 Query: 425 EYRGEIKIGLTFTP----EEARDEDQPEENYGGW 514 +G +++ + + P ++ + DQ ++ GW Sbjct: 141 RVKGFLRLKMAYMPKNGGQDEENSDQRDDMEHGW 174
>SYT7_MOUSE (Q9R0N7) Synaptotagmin-7 (Synaptotagmin VII) (SytVII)| Length = 403 Score = 47.4 bits (111), Expect = 3e-05 Identities = 33/113 (29%), Positives = 53/113 (46%), Gaps = 6/113 (5%) Frame = +2 Query: 53 RSWVGEGEIRPGEKMAQGTLEVLLVGAKGLENTDYLCNMDPYA--VLRCTSQEQKSTVAS 226 R +G + G + TL V ++ A+ L D+ DP+ L + + T Sbjct: 133 RENLGRIQFSVGYNFQESTLTVKVMKAQELPAKDFSGTSDPFVKIYLLPDKKHKLETKVK 192 Query: 227 GKGSDPEWNETFVFT----VSENARELVIKLLDSDGGTEDDSVGEATIPLDGV 373 K +P WNETF+F R L +++LD D + +D +GE +IPL+ V Sbjct: 193 RKNLNPHWNETFLFEGFPYEKVVQRVLYLQVLDYDRFSRNDPIGEVSIPLNKV 245 Score = 36.2 bits (82), Expect = 0.077 Identities = 24/85 (28%), Positives = 45/85 (52%), Gaps = 7/85 (8%) Frame = +2 Query: 116 VLLVGAKGLENTDYLCNMDPYA----VLRCTSQEQKSTVASGKGSDPEWNETFVFTV-SE 280 V ++ A+ L+ D DPY + + E+K TV + +P +NE+F F + +E Sbjct: 285 VNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVTKKRNLNPIFNESFAFDIPTE 344 Query: 281 NARE--LVIKLLDSDGGTEDDSVGE 349 RE ++I ++D D + +D +G+ Sbjct: 345 KLRETTIIITVMDKDKLSRNDVIGK 369
>NED4L_PONPY (Q5RBF2) E3 ubiquitin-protein ligase NEDD4-like protein (EC| 6.3.2.-) Length = 959 Score = 47.4 bits (111), Expect = 3e-05 Identities = 37/154 (24%), Positives = 64/154 (41%), Gaps = 19/154 (12%) Frame = +2 Query: 110 LEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKSTVAS------GKGSDPEWNETFVFT 271 L V +V L D DPY L ++ +A K +P+WNE F F Sbjct: 26 LRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQTKTIKKTLNPKWNEEFYFR 85 Query: 272 VSENARELVIKLLDSDGGTEDDSVGEATIPLDGVYTEGSIPPTVYNVVKD---------E 424 V+ + L+ ++ D + T DD +G+ +PL + TE Y KD Sbjct: 86 VNPSNHRLLFEVFDENRLTRDDFLGQVDVPLSHLPTEDPTMERPY-TFKDFLLRPRSHKS 144 Query: 425 EYRGEIKIGLTFTP----EEARDEDQPEENYGGW 514 +G +++ + + P +E + +Q ++ GW Sbjct: 145 RVKGFLRLKMAYMPKNGGQEEENSEQRDDMEHGW 178
>NED4L_MOUSE (Q8CFI0) E3 ubiquitin-protein ligase NEDD4-like protein (EC| 6.3.2.-) (Nedd4-2) (NEDD4.2) Length = 1004 Score = 47.0 bits (110), Expect = 4e-05 Identities = 40/161 (24%), Positives = 67/161 (41%), Gaps = 16/161 (9%) Frame = +2 Query: 65 GEGEIRPGEKMAQGTLEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKSTVAS------ 226 G+GE R L V +V L D DPY L ++ +A Sbjct: 43 GQGESR--------ILRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQTKTI 94 Query: 227 GKGSDPEWNETFVFTVSENARELVIKLLDSDGGTEDDSVGEATIPLDGVYTEGSIPPTVY 406 K +P+WNE F F V+ + L+ ++ D + T DD +G+ +PL + TE Y Sbjct: 95 KKTLNPKWNEEFYFRVNPSNHRLLFEVFDENRLTRDDFLGQVDVPLSHLPTEDPTMERPY 154 Query: 407 NVVKD---------EEYRGEIKIGLTFTPEE-ARDEDQPEE 499 KD +G +++ + + P+ +DE+ E+ Sbjct: 155 -TFKDFLLRPRSHKSRVKGFLRLKMAYMPKNGGQDEENSEQ 194
>RSP5_YEAST (P39940) E3 ubiquitin--protein ligase RSP5 (EC 6.3.2.-)| Length = 809 Score = 46.2 bits (108), Expect = 7e-05 Identities = 26/69 (37%), Positives = 36/69 (52%) Frame = +2 Query: 107 TLEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKSTVASGKGSDPEWNETFVFTVSENA 286 ++ V LV A+ L D + DP+AVL + KST A+ K +P WNETF F Sbjct: 4 SISVKLVAAESLYKRDVFRSPDPFAVLTIDGYQTKSTSAAKKTLNPYWNETFKFDDINEN 63 Query: 287 RELVIKLLD 313 L I++ D Sbjct: 64 SILTIQVFD 72
>SYT7_HUMAN (O43581) Synaptotagmin-7 (Synaptotagmin VII) (SytVII)| Length = 402 Score = 46.2 bits (108), Expect = 7e-05 Identities = 32/113 (28%), Positives = 53/113 (46%), Gaps = 6/113 (5%) Frame = +2 Query: 53 RSWVGEGEIRPGEKMAQGTLEVLLVGAKGLENTDYLCNMDPYA--VLRCTSQEQKSTVAS 226 R +G + G + TL + ++ A+ L D+ DP+ L + + T Sbjct: 132 RENLGRIQFSVGYNFQESTLTLKIMKAQELPAKDFSGTSDPFVKIYLLPDKKHKLKTKVK 191 Query: 227 GKGSDPEWNETFVFT----VSENARELVIKLLDSDGGTEDDSVGEATIPLDGV 373 K +P WNETF+F R L +++LD D + +D +GE +IPL+ V Sbjct: 192 RKNLNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVSIPLNKV 244 Score = 37.0 bits (84), Expect = 0.045 Identities = 24/85 (28%), Positives = 45/85 (52%), Gaps = 7/85 (8%) Frame = +2 Query: 116 VLLVGAKGLENTDYLCNMDPYA----VLRCTSQEQKSTVASGKGSDPEWNETFVFTV-SE 280 V ++ A+ L+ D DPY + + E+K TV + +P +NE+F F + +E Sbjct: 284 VNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVTMKRNLNPNFNESFAFDIPTE 343 Query: 281 NARE--LVIKLLDSDGGTEDDSVGE 349 RE ++I ++D D + +D +G+ Sbjct: 344 KLRETTIIITVMDKDKLSRNDVIGK 368
>PUB1_SCHPO (Q92462) E3 ubiquitin--protein ligase pub1 (EC 6.3.2.-)| Length = 767 Score = 44.3 bits (103), Expect = 3e-04 Identities = 24/68 (35%), Positives = 37/68 (54%) Frame = +2 Query: 110 LEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKSTVASGKGSDPEWNETFVFTVSENAR 289 + V +V A GL D DP+AVL ++ +T A K +P WNETF V++N+ Sbjct: 10 IRVTIVAADGLYKRDVFRFPDPFAVLTVDGEQTHTTTAIKKTLNPYWNETFEVNVTDNS- 68 Query: 290 ELVIKLLD 313 + I++ D Sbjct: 69 TIAIQVFD 76
>YMH2_YEAST (Q03640) Hypothetical 171.1 kDa protein in RPL6A-DAK1 intergenic| region Length = 1545 Score = 43.5 bits (101), Expect = 5e-04 Identities = 29/123 (23%), Positives = 56/123 (45%), Gaps = 1/123 (0%) Frame = +2 Query: 104 GTLEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKSTVASGKGSDPEWNETFVFTV-SE 280 G L + L+ GL++ D DP+ + ++ + K DP WNE + S Sbjct: 1134 GYLNIKLISGHGLKSADRNGYSDPFVHIFVNDKKVFKSNIKKKTLDPVWNEDAKIPILSR 1193 Query: 281 NARELVIKLLDSDGGTEDDSVGEATIPLDGVYTEGSIPPTVYNVVKDEEYRGEIKIGLTF 460 + +++ +LD D ++D +G+A++ + + YN + +G IK+ +F Sbjct: 1194 SKNQVIFNVLDWDRAGDNDDLGQASLDVSSLEV-----GKTYNWNLNLNTQGSIKLQGSF 1248 Query: 461 TPE 469 PE Sbjct: 1249 NPE 1251 Score = 43.1 bits (100), Expect = 6e-04 Identities = 34/143 (23%), Positives = 66/143 (46%), Gaps = 7/143 (4%) Frame = +2 Query: 92 KMAQGTLEVLLVGAKGLENTDYLCN-MDPYAVLRC------TSQEQKSTVASGKGSDPEW 250 K A G L V + A L+ +D++ N +DPY V+ T +E ++++ S +P W Sbjct: 487 KEAIGVLAVTIASADSLKGSDFITNTVDPYIVMTTEDAVPGTDEEVRTSIKSNV-KNPRW 545 Query: 251 NETFVFTVSENARELVIKLLDSDGGTEDDSVGEATIPLDGVYTEGSIPPTVYNVVKDEEY 430 NET ++ ++L +K D + +D +G+ + L + + + + Sbjct: 546 NETKYLLLNTLEQKLNLKCFDFNDVRKDTVIGDLQLDLADLLQNPVLDNQTAELRSGTKS 605 Query: 431 RGEIKIGLTFTPEEARDEDQPEE 499 +G + L + P + ED+ EE Sbjct: 606 KGILHYSLHWFPVK---EDKSEE 625 Score = 31.2 bits (69), Expect = 2.5 Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 2/84 (2%) Frame = +2 Query: 68 EGEIRPGEKMAQGTLEVLLVGAKGLENTDYLC-NMDPYAVLRCTSQEQKSTVASGKGSDP 244 E E + G ++ L K L+ T + ++ P A L Q+ KS + ++P Sbjct: 651 EDENEESSQTDVGIAKITLQKVKYLDTTSSMTGSLSPCAELFIDGQKVKSYRTLRRINEP 710 Query: 245 EWNETF-VFTVSENARELVIKLLD 313 WNET V S++ + V+K+ D Sbjct: 711 SWNETIEVLVPSKSNSKFVLKIFD 734
>YNI7_YEAST (P48231) Hypothetical 132.5 kDa protein in TOP2-MKT1 intergenic| region Length = 1178 Score = 42.7 bits (99), Expect = 8e-04 Identities = 33/148 (22%), Positives = 62/148 (41%), Gaps = 16/148 (10%) Frame = +2 Query: 104 GTLEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKSTVASGKGSDPEWNETFVFTVSEN 283 G L V + A+ L N D L + PYA + + T + +P WN++ +V+ Sbjct: 650 GMLRVFINKAENLRNPDSLGKISPYAKVSVNGVARGRTNERIETLNPIWNQSIYVSVTSP 709 Query: 284 ARELVIKLLDSDGGTEDDSVGEATIPLDGVYTEGS---------IPPTVYNVVKDEEYRG 436 +++ I D +D ++G I +Y + + P N++ + +G Sbjct: 710 LQKVSIDCFGIDTNGDDHNLGSLNIQTQNIYHKDNDDKYTIFIDNAPRTGNLIGKKGVKG 769 Query: 437 EIKIGLTFTP-------EEARDEDQPEE 499 + L+F P EEA++ D+ E Sbjct: 770 TVTYYLSFYPVVPVLSLEEAKEVDEINE 797 Score = 36.6 bits (83), Expect = 0.059 Identities = 31/141 (21%), Positives = 52/141 (36%), Gaps = 4/141 (2%) Frame = +2 Query: 104 GTLEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQK---STVASGKGSDPEWNETFVFTV 274 G L++ A+ L + DPY + T K +P WNE+ V Sbjct: 983 GDLKITAKSAENLIGVNKNGYSDPYVEFFLNEKSTSPFFKTAVQKKTLNPTWNESKTIEV 1042 Query: 275 SENARE-LVIKLLDSDGGTEDDSVGEATIPLDGVYTEGSIPPTVYNVVKDEEYRGEIKIG 451 S + L I + D + + S+G+A +PL + E + V E G + + Sbjct: 1043 SNRVNDYLTINVKDYESTNSNRSIGKAVVPLSTIDPESDTTFNIPLVGPKGEDGGVLHLE 1102 Query: 452 LTFTPEEARDEDQPEENYGGW 514 F P + + E G + Sbjct: 1103 FEFEPRYTTNVVKREAGLGNF 1123 Score = 33.5 bits (75), Expect = 0.50 Identities = 25/123 (20%), Positives = 46/123 (37%), Gaps = 2/123 (1%) Frame = +2 Query: 104 GTLEVLLVGAKGLENTDYLCN--MDPYAVLRCTSQEQKSTVASGKGSDPEWNETFVFTVS 277 G LE+ + A GL + +DPY + + T ++P WNE+ + Sbjct: 378 GVLEIKVKNAHGLRKLVGMIKKTVDPYLTFELSGKIVGKTKVFKNSANPVWNESIYILLQ 437 Query: 278 ENARELVIKLLDSDGGTEDDSVGEATIPLDGVYTEGSIPPTVYNVVKDEEYRGEIKIGLT 457 L I + D D +G L+ ++ + +++ + GE+ L Sbjct: 438 SFTDPLTIAVYDKRETLSDKKMGTVIFNLNKLHANHYHKNEKVHFLRNSKPVGELTFDLR 497 Query: 458 FTP 466 F P Sbjct: 498 FFP 500
>RBF1_CAEEL (P41885) Rabphilin-1| Length = 1106 Score = 41.6 bits (96), Expect = 0.002 Identities = 38/143 (26%), Positives = 63/143 (44%), Gaps = 18/143 (12%) Frame = +2 Query: 98 AQGTLEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKSTVASGKGSD----PEWNETF- 262 A L++ L+ AK L+ D DPY K+T + K + PEWNE Sbjct: 840 ADKKLKMHLIRAKNLKAMDSNGFSDPYVKFHLLPGNTKATKLTSKTIEKTLNPEWNEEMS 899 Query: 263 VFTVSENARE---LVIKLLDSDGGTEDDSVGEATIPLD----------GVYTEGSIPPTV 403 + ++E+ +E L + +LD D D +GE I L +Y E ++P Sbjct: 900 YYGITEDDKEKKILRVTVLDRDR-IGSDFLGETRIALKKLNDNEMKKFNLYLESALPVPQ 958 Query: 404 YNVVKDEEYRGEIKIGLTFTPEE 472 ++ E RG+I +GL + ++ Sbjct: 959 QTKEEENEDRGKINVGLQYNIQQ 981 Score = 31.2 bits (69), Expect = 2.5 Identities = 23/77 (29%), Positives = 34/77 (44%), Gaps = 7/77 (9%) Frame = +2 Query: 137 GLENTDYLCNMDPYAVLRCTSQEQKS----TVASGKGSDPEWNETFVFTVSEN---AREL 295 G+++T + DPY + T K+ T + +PEWNE F V + L Sbjct: 996 GMDSTGF---SDPYCKVSLTPITSKAHRAKTSTKKRTLNPEWNEQLQFVVPFKDLPKKTL 1052 Query: 296 VIKLLDSDGGTEDDSVG 346 I + D D G DD +G Sbjct: 1053 QIGVYDHDLGKHDDYIG 1069
>RASL2_HUMAN (O43374) Ras GTPase-activating protein 4 (RasGAP-activating-like| protein 2) (Calcium-promoted Ras inactivator) Length = 803 Score = 40.8 bits (94), Expect = 0.003 Identities = 29/125 (23%), Positives = 53/125 (42%), Gaps = 3/125 (2%) Frame = +2 Query: 101 QGTLEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKSTVASGKGSDPEWNETFVFTVSE 280 + +L + +V K L D + DPY +++ ++ T K P W E + + Sbjct: 4 RSSLYIRIVEGKNLPAKDITGSSDPYCIVKVDNEPIIRTATVWKTLCPFWGEEYQVHLPP 63 Query: 281 NARELVIKLLDSDGGTEDDSVGEATIPLDGVYTEG---SIPPTVYNVVKDEEYRGEIKIG 451 + ++D D + DD +G+ + D + + S + V DEE +GEI + Sbjct: 64 TFHAVAFYVMDEDALSRDDVIGKVCLTRDTIASHPKGFSGWAHLTEVDPDEEVQGEIHLR 123 Query: 452 LTFTP 466 L P Sbjct: 124 LEVWP 128 Score = 39.3 bits (90), Expect = 0.009 Identities = 27/96 (28%), Positives = 48/96 (50%), Gaps = 1/96 (1%) Frame = +2 Query: 74 EIRPGEKMAQGTLEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKSTVASGKGSDPEWN 253 E+ PG + + L ++ A+ L D DP+ +R + +++++ K P WN Sbjct: 125 EVWPGARACR--LRCSVLEARDLAPKDRNGTSDPFVRVRYKGRTRETSIVK-KSCYPRWN 181 Query: 254 ETFVFTVSENARE-LVIKLLDSDGGTEDDSVGEATI 358 ETF F + E A E L ++ D D + +D +G+ I Sbjct: 182 ETFEFELQEGAMEALCVEAWDWDLVSRNDFLGKVVI 217
>TMM24_HUMAN (O14523) Transmembrane protein 24 (Protein DLNB23)| Length = 706 Score = 40.8 bits (94), Expect = 0.003 Identities = 23/75 (30%), Positives = 38/75 (50%) Frame = +2 Query: 140 LENTDYLCNMDPYAVLRCTSQEQKSTVASGKGSDPEWNETFVFTVSENARELVIKLLDSD 319 LE T+ LC + +QK T + GS+ EW E + +REL +K+L S Sbjct: 302 LEGTEELCCVAELD----NPMQQKWTKPARAGSEVEWTEDLALDLGPQSRELTLKVLRSS 357 Query: 320 GGTEDDSVGEATIPL 364 + + +G+AT+P+ Sbjct: 358 SCGDTELLGQATLPV 372
>RASL1_MOUSE (Q9Z268) RasGAP-activating-like protein 1| Length = 799 Score = 40.8 bits (94), Expect = 0.003 Identities = 28/128 (21%), Positives = 56/128 (43%), Gaps = 3/128 (2%) Frame = +2 Query: 104 GTLEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKSTVASGKGSDPEWNETFVFTVSEN 283 G+L + +V + L D + DPY +++ Q T + P W E + + + Sbjct: 5 GSLSIRVVEGRALPAKDVSGSSDPYCLVKVDDQVVARTATIWRSLSPFWGEEYTVHLPLD 64 Query: 284 ARELVIKLLDSDGGTEDDSVGEATIPLDGVYTEGSIPPTVYNVVK---DEEYRGEIKIGL 454 L +LD D DD +G+ ++ + + + + N+ + D E +GE+ + + Sbjct: 65 FHHLAFYVLDEDTVGHDDIIGKISLSKEAITADPRGIDSWINLSRVDPDAEVQGEVCLDV 124 Query: 455 TFTPEEAR 478 E+AR Sbjct: 125 KLL-EDAR 131
>NEDD4_DROME (Q9VVI3) E3 ubiquitin-protein ligase Nedd-4 (EC 6.3.2.-) (DNedd4)| Length = 1007 Score = 40.4 bits (93), Expect = 0.004 Identities = 25/97 (25%), Positives = 43/97 (44%), Gaps = 6/97 (6%) Frame = +2 Query: 110 LEVLLVGAKGLENTDYLCNMDPYAVLRCTSQ------EQKSTVASGKGSDPEWNETFVFT 271 L ++++ + L D DPY + + + T K +P WNE F+F Sbjct: 72 LRIVVLTGQSLAKKDIFGASDPYVRIDLNTINGDINIDSVLTKTKKKTLNPTWNEEFIFR 131 Query: 272 VSENARELVIKLLDSDGGTEDDSVGEATIPLDGVYTE 382 V + +LV ++ D + T DD +G + L + TE Sbjct: 132 VKPSEHKLVFQVFDENRLTRDDFLGMVELTLVNLPTE 168
>SYT5_RAT (P47861) Synaptotagmin-5 (Synaptotagmin V) (SytV) (Synaptotagmin| IX) Length = 386 Score = 40.0 bits (92), Expect = 0.005 Identities = 34/134 (25%), Positives = 60/134 (44%), Gaps = 13/134 (9%) Frame = +2 Query: 104 GTLEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQK--STVASGKGSDPEWNETFVFTVS 277 G L V ++ A+GL D + DPY + +++ T + +P + ETF F V Sbjct: 123 GQLLVGILQAEGLAALDLGGSSDPYVSVYLLPDKRRRHETKVHRQTLNPHFGETFAFKVP 182 Query: 278 E---NARELVIKLLDSDGGTEDDSVGEATIPLDGV--------YTEGSIPPTVYNVVKDE 424 R LV+ + D D + +D++GE +P+ V + E + P +++ Sbjct: 183 YVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVNLGRPVQAWRELQVAPK-----EEQ 237 Query: 425 EYRGEIKIGLTFTP 466 E G+I L + P Sbjct: 238 EKLGDICFSLRYVP 251
>SYT5_MOUSE (Q9R0N5) Synaptotagmin-5 (Synaptotagmin V) (SytV) (Synaptotagmin| IX) Length = 386 Score = 40.0 bits (92), Expect = 0.005 Identities = 34/134 (25%), Positives = 60/134 (44%), Gaps = 13/134 (9%) Frame = +2 Query: 104 GTLEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQK--STVASGKGSDPEWNETFVFTVS 277 G L V ++ A+GL D + DPY + +++ T + +P + ETF F V Sbjct: 123 GQLLVGILQAQGLAALDLGGSSDPYVSVYLLPDKRRRHETKVHRQTLNPHFGETFAFKVP 182 Query: 278 E---NARELVIKLLDSDGGTEDDSVGEATIPLDGV--------YTEGSIPPTVYNVVKDE 424 R LV+ + D D + +D++GE +P+ V + E + P +++ Sbjct: 183 YVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVNLGRPVQAWRELQVAPK-----EEQ 237 Query: 425 EYRGEIKIGLTFTP 466 E G+I L + P Sbjct: 238 EKLGDICFSLRYVP 251
>TOLIP_MOUSE (Q9QZ06) Toll-interacting protein| Length = 274 Score = 40.0 bits (92), Expect = 0.005 Identities = 27/122 (22%), Positives = 52/122 (42%), Gaps = 2/122 (1%) Frame = +2 Query: 104 GTLEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKSTVASGKGSDPEWNETFVFTVSEN 283 G L + +V AK +N + MDPY LR ++ A +P WN+ TV Sbjct: 53 GRLSITVVQAKLAKNYG-MTRMDPYCRLRLGYAVYETPTAHNGAKNPRWNKVIQCTVPPG 111 Query: 284 ARELVIKLLDSDGGTEDDSVGEATIPLDGVYTEGSIPPTVYNVV--KDEEYRGEIKIGLT 457 +++ D + DD + I + +G + Y++ + ++ G I + ++ Sbjct: 112 VDSFYLEIFDERAFSMDDRIAWTHITIPESLKQGQVEDEWYSLSGRQGDDKEGMINLVMS 171 Query: 458 FT 463 +T Sbjct: 172 YT 173
>PUB3_SCHPO (O14326) E3 ubiquitin--protein ligase pub3 (EC 6.3.2.-)| Length = 786 Score = 39.7 bits (91), Expect = 0.007 Identities = 25/75 (33%), Positives = 36/75 (48%), Gaps = 2/75 (2%) Frame = +2 Query: 95 MAQGTLEV--LLVGAKGLENTDYLCNMDPYAVLRCTSQEQKSTVASGKGSDPEWNETFVF 268 M QG V +V A GL D DP+A+L ++ +T K +P WNE F Sbjct: 1 MEQGAKRVRFYIVAADGLSKRDLFRQPDPFAILTVDGEQTHTTKVIKKSVNPYWNEGFEV 60 Query: 269 TVSENARELVIKLLD 313 TV ++ + I+L D Sbjct: 61 TVKPSS-VISIRLFD 74
>RFIP5_HUMAN (Q9BXF6) Rab11 family-interacting protein 5 (Rab11-FIP5)| (Rab11-interacting protein Rip11) (Gamma-SNAP-associated factor 1) (Gaf-1) (Phosphoprotein pp75) Length = 653 Score = 38.9 bits (89), Expect = 0.012 Identities = 33/149 (22%), Positives = 64/149 (42%), Gaps = 31/149 (20%) Frame = +2 Query: 110 LEVLLVGAKGL--ENTDYLCNMDPYAVLRCTSQEQKSTVASGKGSDPEWNETFVFTVSEN 283 ++V ++ A+GL +++ D Y V++ ++ ++V PEW E F + Sbjct: 21 VQVTVLRARGLRGKSSGAGSTSDAYTVIQVGREKYSTSVVEKTHGCPEWREECSFELPPG 80 Query: 284 ARELVIKLLDSDGGTE------------------------DDSVGEATIPLDGVYTEGSI 391 A + +++ ++D G D +G+AT+ LD V+ G Sbjct: 81 ALDGLLRAQEADAGPAPWAASSAAACELVLTTMHRSLIGVDKFLGQATVALDEVFGAGRA 140 Query: 392 PPTVYNVV-----KDEEYRGEIKIGLTFT 463 T + + K E+ RGEI++ + FT Sbjct: 141 QHTQWYKLHSKPGKKEKERGEIEVTIQFT 169
>PA24A_MOUSE (P47713) Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group| IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase); Lysophospholipase (EC 3.1.1.5)] Length = 748 Score = 38.9 bits (89), Expect = 0.012 Identities = 30/94 (31%), Positives = 44/94 (46%), Gaps = 4/94 (4%) Frame = +2 Query: 152 DYLCNMDPYAVL--RCTSQEQKSTVASGKGSDPEWNETFVFTVSENARE-LVIKLLDSDG 322 D L DPY L T +K T +P WNETF F + N L I L+D++ Sbjct: 37 DMLDTPDPYVELFISTTPDSRKRTRHFNNDINPVWNETFEFILDPNQENVLEITLMDAN- 95 Query: 323 GTEDDSVGEATIPLDGVYT-EGSIPPTVYNVVKD 421 D+++G AT P+ + E P ++N V + Sbjct: 96 YVMDETLGTATFPVSSMKVGEKKEVPFIFNQVTE 129
>PA24A_RAT (P50393) Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group| IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase); Lysophospholipase (EC 3.1.1.5)] Length = 752 Score = 38.9 bits (89), Expect = 0.012 Identities = 30/94 (31%), Positives = 44/94 (46%), Gaps = 4/94 (4%) Frame = +2 Query: 152 DYLCNMDPYAVL--RCTSQEQKSTVASGKGSDPEWNETFVFTVSENARE-LVIKLLDSDG 322 D L DPY L T +K T +P WNETF F + N L I L+D++ Sbjct: 37 DMLDTPDPYVELFISTTPDSRKRTRHFNNDINPVWNETFEFILDPNQENVLEITLMDAN- 95 Query: 323 GTEDDSVGEATIPLDGVYT-EGSIPPTVYNVVKD 421 D+++G AT P+ + E P ++N V + Sbjct: 96 YVMDETLGTATFPVSSMKVGEKKEVPFIFNQVTE 129
>RASL1_HUMAN (O95294) RasGAP-activating-like protein 1| Length = 804 Score = 38.1 bits (87), Expect = 0.020 Identities = 25/115 (21%), Positives = 50/115 (43%), Gaps = 3/115 (2%) Frame = +2 Query: 107 TLEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKSTVASGKGSDPEWNETFVFTVSENA 286 +L V +V + L D + DPY +++ + T + P W E + + + Sbjct: 6 SLNVRVVEGRALPAKDVSGSSDPYCLVKVDDEVVARTATVWRSLGPFWGEEYTVHLPLDF 65 Query: 287 RELVIKLLDSDGGTEDDSVGEATIPLDGVYTEGSIPPTVYNVVK---DEEYRGEI 442 +L +LD D DD +G+ ++ + + + + N+ + D E +GEI Sbjct: 66 HQLAFYVLDEDTVGHDDIIGKISLSREAITADPRGIDSWINLSRVDPDAEVQGEI 120
>TOLIP_HUMAN (Q9H0E2) Toll-interacting protein| Length = 274 Score = 37.7 bits (86), Expect = 0.026 Identities = 24/103 (23%), Positives = 42/103 (40%) Frame = +2 Query: 104 GTLEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKSTVASGKGSDPEWNETFVFTVSEN 283 G L + +V AK +N + MDPY LR ++ A +P WN+ TV Sbjct: 53 GRLNITVVQAKLAKNYG-MTRMDPYCRLRLGYAVYETPTAHNGAKNPRWNKVIHCTVPPG 111 Query: 284 ARELVIKLLDSDGGTEDDSVGEATIPLDGVYTEGSIPPTVYNV 412 +++ D + DD + I + +G + Y++ Sbjct: 112 VDSFYLEIFDERAFSMDDRIAWTHITIPESLRQGKVEDKWYSL 154
>KPCA_HUMAN (P17252) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 37.7 bits (86), Expect = 0.026 Identities = 33/125 (26%), Positives = 56/125 (44%), Gaps = 11/125 (8%) Frame = +2 Query: 5 EVAVQSCCLLNV-----VPHLRSWVGEGEIRPGEKMAQGTLEVLLVGAKGLENTDYLCNM 169 ++ V C++NV + H G I ++A L V + AK L D Sbjct: 135 DMNVHKQCVINVPSLCGMDHTEK---RGRIYLKAEVADEKLHVTVRDAKNLIPMDPNGLS 191 Query: 170 DPYAVLRCT----SQEQKSTVASGKGSDPEWNETFVFTV--SENARELVIKLLDSDGGTE 331 DPY L+ ++ ++ T +P+WNE+F F + S+ R L +++ D D T Sbjct: 192 DPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRLSVEIWDWDRTTR 251 Query: 332 DDSVG 346 +D +G Sbjct: 252 NDFMG 256
>SYT5_HUMAN (O00445) Synaptotagmin-5 (Synaptotagmin V) (SytV)| Length = 386 Score = 37.7 bits (86), Expect = 0.026 Identities = 27/95 (28%), Positives = 45/95 (47%), Gaps = 5/95 (5%) Frame = +2 Query: 104 GTLEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQK--STVASGKGSDPEWNETFVFTVS 277 G L V ++ A GL D + DPY + +++ T + +P + ETF F V Sbjct: 123 GQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFKVP 182 Query: 278 E---NARELVIKLLDSDGGTEDDSVGEATIPLDGV 373 R LV+ + D D + +D++GE +P+ V Sbjct: 183 YVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSV 217
>PA24A_HORSE (O77793) Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group| IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase); Lysophospholipase (EC 3.1.1.5)] Length = 749 Score = 37.4 bits (85), Expect = 0.034 Identities = 30/94 (31%), Positives = 43/94 (45%), Gaps = 4/94 (4%) Frame = +2 Query: 152 DYLCNMDPYAVL--RCTSQEQKSTVASGKGSDPEWNETFVFTVSENARE-LVIKLLDSDG 322 D L DPY L T +K T +P WNETF F + N L I L+D++ Sbjct: 37 DMLDTPDPYVELFISSTPDSRKRTRHFNNNINPVWNETFEFILDPNQENVLEITLMDAN- 95 Query: 323 GTEDDSVGEATIPLDGVYT-EGSIPPTVYNVVKD 421 D+++G AT L + E P ++N V + Sbjct: 96 YVMDETLGTATFTLSSMKVGEKKEVPFIFNQVTE 129
>KPC2_CAEEL (P90980) Protein kinase C-like 2 (EC 2.7.11.13) (PKC2)| Length = 682 Score = 37.0 bits (84), Expect = 0.045 Identities = 36/149 (24%), Positives = 66/149 (44%), Gaps = 9/149 (6%) Frame = +2 Query: 71 GEIRPGEKMAQGTLEVLLVGAKGLENTDYLCNMDPYAVLR-------CTSQEQKSTVASG 229 G +R + L + ++ AK L D DPY + C S+++ T+ + Sbjct: 162 GRLRIEAHIENDQLTIKILEAKNLIPMDPNGLSDPYVKCKLIPEDSGCKSKQKTKTLRAT 221 Query: 230 KGSDPEWNETFVFTV--SENARELVIKLLDSDGGTEDDSVGEATIPLDGVYTEGSIPPTV 403 +P+WNETF + + + R L I++ D D + +D +G + + + E + Sbjct: 222 L--NPQWNETFTYKLLPGDKDRRLSIEVWDWDRTSRNDFMGSLSFGISELMKEAA--SGW 277 Query: 404 YNVVKDEEYRGEIKIGLTFTPEEARDEDQ 490 Y ++ EE GE + TPE D ++ Sbjct: 278 YKLLSAEE--GEF-YNINITPEYDEDMEK 303
>DYSF_HUMAN (O75923) Dysferlin (Dystrophy-associated fer-1-like protein)| (Fer-1-like protein 1) Length = 2080 Score = 37.0 bits (84), Expect = 0.045 Identities = 25/89 (28%), Positives = 40/89 (44%), Gaps = 10/89 (11%) Frame = +2 Query: 110 LEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKSTVASGKGSDPEWNETFVF------- 268 L + A+ L D DPYA++ Q QK+ V +P W++T +F Sbjct: 1154 LRCYMYQARDLAAMDKDSFSDPYAIVSFLHQSQKTVVVKNT-LNPTWDQTLIFYEIEIFG 1212 Query: 269 ---TVSENARELVIKLLDSDGGTEDDSVG 346 TV+E +V++L D D D+ +G Sbjct: 1213 EPATVAEQPPSIVVELYDHDTYGADEFMG 1241 Score = 30.0 bits (66), Expect = 5.5 Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 5/72 (6%) Frame = +2 Query: 182 VLRCTSQEQKSTVASGKGSDPEWNETFVFTVSENAREL-----VIKLLDSDGGTEDDSVG 346 V++ T+ Q KG+ P +NET F + ++ EL I ++DS D +G Sbjct: 240 VVKVTAAGQTKRTRIHKGNSPLFNETLFFNLFDSPGELFDEPIFITVVDSRSLRTDALLG 299 Query: 347 EATIPLDGVYTE 382 E + + +Y E Sbjct: 300 EFRMDVGTIYRE 311
>SYTL5_HUMAN (Q8TDW5) Synaptotagmin-like protein 5| Length = 730 Score = 37.0 bits (84), Expect = 0.045 Identities = 30/116 (25%), Positives = 50/116 (43%), Gaps = 12/116 (10%) Frame = +2 Query: 197 SQEQKSTVASGKGSDPEWNETFVFTVSE---NARELVIKLLDSDGGTEDDSVGEATIPLD 367 S+ K G++PE+NET +T+S R L + + D + +GE IP D Sbjct: 456 SRNNKRKTKIRTGTNPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFD 515 Query: 368 GVYTEGSIPPTVYNVVKDE---------EYRGEIKIGLTFTPEEARDEDQPEENYG 508 E P + V++ + +Y+GE+ + L + P E PE+ G Sbjct: 516 SWNFEN--PTDEWFVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQG 569
>KPCA_MOUSE (P20444) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 36.6 bits (83), Expect = 0.059 Identities = 27/98 (27%), Positives = 45/98 (45%), Gaps = 6/98 (6%) Frame = +2 Query: 71 GEIRPGEKMAQGTLEVLLVGAKGLENTDYLCNMDPYAVLRCT----SQEQKSTVASGKGS 238 G I ++ L V + AK L D DPY L+ ++ ++ T Sbjct: 159 GRIYLKAEVTDEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSNL 218 Query: 239 DPEWNETFVFTV--SENARELVIKLLDSDGGTEDDSVG 346 +P+WNE+F F + S+ R L +++ D D T +D +G Sbjct: 219 NPQWNESFTFKLKPSDKDRRLSVEIWDWDRTTRNDFMG 256
>KPCB_RAT (P68403) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 670 Score = 36.6 bits (83), Expect = 0.059 Identities = 30/100 (30%), Positives = 47/100 (47%), Gaps = 9/100 (9%) Frame = +2 Query: 113 EVLLV---GAKGLENTDYLCNMDPYAVLRCT----SQEQKSTVASGKGSDPEWNETFVFT 271 EVL+V AK L D DPY L+ S+ ++ T +PEWNETF F Sbjct: 170 EVLIVVVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQ 229 Query: 272 V--SENARELVIKLLDSDGGTEDDSVGEATIPLDGVYTEG 385 + S+ R L +++ D D + +D +G + + + G Sbjct: 230 LKESDKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKAG 269
>KPCB_RABIT (P05772) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 670 Score = 36.6 bits (83), Expect = 0.059 Identities = 30/100 (30%), Positives = 47/100 (47%), Gaps = 9/100 (9%) Frame = +2 Query: 113 EVLLV---GAKGLENTDYLCNMDPYAVLRCT----SQEQKSTVASGKGSDPEWNETFVFT 271 EVL+V AK L D DPY L+ S+ ++ T +PEWNETF F Sbjct: 170 EVLIVVVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQ 229 Query: 272 V--SENARELVIKLLDSDGGTEDDSVGEATIPLDGVYTEG 385 + S+ R L +++ D D + +D +G + + + G Sbjct: 230 LKESDKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKAG 269
>KPCB_HUMAN (P05771) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 670 Score = 36.6 bits (83), Expect = 0.059 Identities = 28/85 (32%), Positives = 42/85 (49%), Gaps = 6/85 (7%) Frame = +2 Query: 110 LEVLLVGAKGLENTDYLCNMDPYAVLRCT----SQEQKSTVASGKGSDPEWNETFVFTV- 274 L VL+ AK L D DPY L+ S+ ++ T +PEWNETF F + Sbjct: 172 LIVLVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLK 231 Query: 275 -SENARELVIKLLDSDGGTEDDSVG 346 S+ R L +++ D D + +D +G Sbjct: 232 ESDKDRRLSVEIWDWDLTSRNDFMG 256
>TMM24_MOUSE (Q80X80) Transmembrane protein 24| Length = 706 Score = 36.6 bits (83), Expect = 0.059 Identities = 17/54 (31%), Positives = 29/54 (53%) Frame = +2 Query: 203 EQKSTVASGKGSDPEWNETFVFTVSENARELVIKLLDSDGGTEDDSVGEATIPL 364 +QK T G + EW E + +REL +K+L S + + +G+AT+P+ Sbjct: 319 QQKWTKPMRAGPEVEWTEDLALDLGPQSRELTLKVLRSSSCGDAELLGQATLPV 372
>KPCB_MOUSE (P68404) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 672 Score = 36.6 bits (83), Expect = 0.059 Identities = 30/100 (30%), Positives = 47/100 (47%), Gaps = 9/100 (9%) Frame = +2 Query: 113 EVLLV---GAKGLENTDYLCNMDPYAVLRCT----SQEQKSTVASGKGSDPEWNETFVFT 271 EVL+V AK L D DPY L+ S+ ++ T +PEWNETF F Sbjct: 170 EVLIVVVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQ 229 Query: 272 V--SENARELVIKLLDSDGGTEDDSVGEATIPLDGVYTEG 385 + S+ R L +++ D D + +D +G + + + G Sbjct: 230 LKESDKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKAG 269
>KPCB_BOVIN (P05126) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 672 Score = 36.6 bits (83), Expect = 0.059 Identities = 30/100 (30%), Positives = 47/100 (47%), Gaps = 9/100 (9%) Frame = +2 Query: 113 EVLLV---GAKGLENTDYLCNMDPYAVLRCT----SQEQKSTVASGKGSDPEWNETFVFT 271 EVL+V AK L D DPY L+ S+ ++ T +PEWNETF F Sbjct: 170 EVLIVVVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQ 229 Query: 272 V--SENARELVIKLLDSDGGTEDDSVGEATIPLDGVYTEG 385 + S+ R L +++ D D + +D +G + + + G Sbjct: 230 LKESDKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKAG 269
>KPCA_RAT (P05696) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 36.2 bits (82), Expect = 0.077 Identities = 32/125 (25%), Positives = 55/125 (44%), Gaps = 11/125 (8%) Frame = +2 Query: 5 EVAVQSCCLLNV-----VPHLRSWVGEGEIRPGEKMAQGTLEVLLVGAKGLENTDYLCNM 169 ++ V C++NV + H G I ++ L V + AK L D Sbjct: 135 DMNVHKQCVINVPSLCGMDHTEK---RGRIYLKAEVTDEKLHVTVRDAKNLIPMDPNGLS 191 Query: 170 DPYAVLRCT----SQEQKSTVASGKGSDPEWNETFVFTV--SENARELVIKLLDSDGGTE 331 DPY L+ ++ ++ T +P+WNE+F F + S+ R L +++ D D T Sbjct: 192 DPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRLSVEIWDWDRTTR 251 Query: 332 DDSVG 346 +D +G Sbjct: 252 NDFMG 256
>KPCA_RABIT (P10102) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 36.2 bits (82), Expect = 0.077 Identities = 32/125 (25%), Positives = 55/125 (44%), Gaps = 11/125 (8%) Frame = +2 Query: 5 EVAVQSCCLLNV-----VPHLRSWVGEGEIRPGEKMAQGTLEVLLVGAKGLENTDYLCNM 169 ++ V C++NV + H G I ++ L V + AK L D Sbjct: 135 DMNVHKQCVINVPSLCGMDHTEK---RGRIYLKAEVTDEKLHVTVRDAKNLIPMDPNGLS 191 Query: 170 DPYAVLRCT----SQEQKSTVASGKGSDPEWNETFVFTV--SENARELVIKLLDSDGGTE 331 DPY L+ ++ ++ T +P+WNE+F F + S+ R L +++ D D T Sbjct: 192 DPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRLSVEIWDWDRTTR 251 Query: 332 DDSVG 346 +D +G Sbjct: 252 NDFMG 256
>RFIP5_MOUSE (Q8R361) Rab11 family-interacting protein 5 (Rab11-FIP5)| (Rab11-interacting protein Rip11) Length = 645 Score = 36.2 bits (82), Expect = 0.077 Identities = 33/149 (22%), Positives = 62/149 (41%), Gaps = 31/149 (20%) Frame = +2 Query: 110 LEVLLVGAKGL--ENTDYLCNMDPYAVLRCTSQEQKSTVASGKGSDPEWNETFVFTVSEN 283 ++V ++ A GL +++ D Y V++ ++ ++V PEW E F + Sbjct: 21 VQVTVLRASGLRGKSSGAGSTSDAYTVIQVGREKYSTSVVEKTQGCPEWCEECSFELPPG 80 Query: 284 ARELVIKLLDSDGGTE------------------------DDSVGEATIPLDGVYTEGSI 391 A + +++ ++D G D +G AT+ LD V+ G Sbjct: 81 ALDGLLRAQEADAGPAPWASGPNAACELVLTTMHRSLIGVDKFLGRATVALDEVFRAGRA 140 Query: 392 PPTVYNVV-----KDEEYRGEIKIGLTFT 463 T + + K E+ RGEI++ + FT Sbjct: 141 QHTQWYRLHSKPGKKEKERGEIQVTIQFT 169
>SY65_DROME (P21521) Synaptotagmin (p65)| Length = 474 Score = 36.2 bits (82), Expect = 0.077 Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 6/92 (6%) Frame = +2 Query: 107 TLEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKS--TVASGKGSDPEWNETFVFTVSE 280 +L V ++ A+ L D DPY + ++K T K P +NETF F Sbjct: 208 SLAVTVIQAEELPALDMGGTSDPYVKVYLLPDKKKKFETKVHRKTLSPVFNETFTFKSLP 267 Query: 281 NA----RELVIKLLDSDGGTEDDSVGEATIPL 364 A + LV + D D ++ D +GE +PL Sbjct: 268 YADAMNKTLVFAIFDFDRFSKHDQIGEVKVPL 299
>HKR1_YEAST (P41809) Hansenula MRAKII killer toxin-resistant protein 1| precursor Length = 1802 Score = 35.8 bits (81), Expect = 0.10 Identities = 27/80 (33%), Positives = 41/80 (51%), Gaps = 2/80 (2%) Frame = -3 Query: 300 MTSSRAFSETVNTKVSFHSGSLPFPEATVLFCSCEVHLRTAYGSMLQR*SVFSRPLAPT- 124 ++SS S +++ VS H G PFP A + F S V + + Y S S + + P+ Sbjct: 421 ISSSLYSSPSLSASVSSHFGVAPFPSAYISFSSVPVAVSSTYTS-----SPSASVVVPSA 475 Query: 123 -SSTSSVPCAIFSPGLISPS 67 +S+ SVP A+ S SPS Sbjct: 476 YASSPSVPVAVSSTYTSSPS 495
>UN13A_RAT (Q62768) Unc-13 homolog A (Munc13-1)| Length = 1735 Score = 35.8 bits (81), Expect = 0.10 Identities = 17/70 (24%), Positives = 36/70 (51%) Frame = +2 Query: 110 LEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKSTVASGKGSDPEWNETFVFTVSENAR 289 + + +V A+GL+ D + DPY ++ ++++ G +P W E F F ++ Sbjct: 691 ISITVVCAQGLQAKDKTGSSDPYVTVQVGKTKKRTKTIYGN-LNPVWEENFHFECHNSSD 749 Query: 290 ELVIKLLDSD 319 + +++LD D Sbjct: 750 RIKVRVLDED 759 Score = 34.3 bits (77), Expect = 0.29 Identities = 24/85 (28%), Positives = 39/85 (45%) Frame = +2 Query: 110 LEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKSTVASGKGSDPEWNETFVFTVSENAR 289 + +L VG K + + Y L+ Q KST + +GS P W + F+F ++ Sbjct: 1 MSLLCVGVKKAKFDGAQEKFNTYVTLKV--QNVKSTTIAVRGSQPSWEQDFMFEINRLDL 58 Query: 290 ELVIKLLDSDGGTEDDSVGEATIPL 364 L +++ + G D VG IPL Sbjct: 59 GLTVEVWNK-GLIWDTMVGTVWIPL 82
>SY61_DISOM (P24505) Synaptotagmin A (Synaptic vesicle protein O-p65-A)| Length = 427 Score = 35.8 bits (81), Expect = 0.10 Identities = 26/93 (27%), Positives = 46/93 (49%), Gaps = 5/93 (5%) Frame = +2 Query: 110 LEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKS--TVASGKGSDPEWNETFVFTVSEN 283 L V ++ A L D DPY + ++K T K +P +NE+F+F + + Sbjct: 164 LIVGIIQAAELPALDVGGTSDPYVKVFVLPDKKKKYETKVHRKTLNPVFNESFIFKIPYS 223 Query: 284 ---ARELVIKLLDSDGGTEDDSVGEATIPLDGV 373 + LV+ + D D ++ D +GEA +P++ V Sbjct: 224 ELGGKTLVMAVYDFDRFSKHDVIGEAKVPMNTV 256
>PA24A_HUMAN (P47712) Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group| IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase); Lysophospholipase (EC 3.1.1.5)] Length = 749 Score = 35.8 bits (81), Expect = 0.10 Identities = 29/94 (30%), Positives = 43/94 (45%), Gaps = 4/94 (4%) Frame = +2 Query: 152 DYLCNMDPYAVL--RCTSQEQKSTVASGKGSDPEWNETFVFTVSENARE-LVIKLLDSDG 322 D L DPY L T +K T +P WNETF F + N L I L+D++ Sbjct: 37 DMLDTPDPYVELFISTTPDSRKRTRHFNNDINPVWNETFEFILDPNQENVLEITLMDAN- 95 Query: 323 GTEDDSVGEATIPLDGVYT-EGSIPPTVYNVVKD 421 D+++G AT + + E P ++N V + Sbjct: 96 YVMDETLGTATFTVSSMKVGEKKEVPFIFNQVTE 129
>SYT4_HUMAN (Q9H2B2) Synaptotagmin-4 (Synaptotagmin IV) (SytIV)| Length = 425 Score = 35.4 bits (80), Expect = 0.13 Identities = 36/123 (29%), Positives = 53/123 (43%), Gaps = 13/123 (10%) Frame = +2 Query: 131 AKGLENTD-YLCNMDPYAVLRCTSQEQKS--TVASGKGSDPEWNETFVF------TVSEN 283 A+GL D DPY + +++ T K DP ++ETF F + E Sbjct: 177 ARGLPAMDEQSMTSDPYIKMTILPEKKHKVKTRVLRKTLDPAFDETFTFYGIPYTQIQEL 236 Query: 284 ARELVIKLLDSDGGTEDDSVGEATIPLDGV-YTEGSI---PPTVYNVVKDEEYRGEIKIG 451 A I L D + DD +GE IPL G+ +EG + + V+ RGE+ I Sbjct: 237 ALHFTI--LSFDRFSRDDIIGEVLIPLSGIELSEGKMLMNREIIKRNVRKSSGRGELLIS 294 Query: 452 LTF 460 L + Sbjct: 295 LCY 297
>SYT11_RAT (O08835) Synaptotagmin-11 (Synaptotagmin XI) (SytXI)| Length = 430 Score = 35.4 bits (80), Expect = 0.13 Identities = 30/113 (26%), Positives = 50/113 (44%), Gaps = 10/113 (8%) Frame = +2 Query: 170 DPYAVLRCTSQEQK--STVASGKGSDPEWNETFVF--TVSENARELVIK--LLDSDGGTE 331 DPY + ++ T K DP ++ETF F ++LV+ +L D + Sbjct: 194 DPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSR 253 Query: 332 DDSVGEATIPLDGVYTEGSIPPTVYNVVKDEEY----RGEIKIGLTFTPEEAR 478 DD +GE +PL GV +++K RGE+++ L++ P R Sbjct: 254 DDVIGEVMVPLAGVDPSTGKVQLTRDIIKRNIQKCISRGELQVSLSYQPVAQR 306
>SYT11_MOUSE (Q9R0N3) Synaptotagmin-11 (Synaptotagmin XI) (SytXI)| Length = 430 Score = 35.4 bits (80), Expect = 0.13 Identities = 30/113 (26%), Positives = 50/113 (44%), Gaps = 10/113 (8%) Frame = +2 Query: 170 DPYAVLRCTSQEQK--STVASGKGSDPEWNETFVF--TVSENARELVIK--LLDSDGGTE 331 DPY + ++ T K DP ++ETF F ++LV+ +L D + Sbjct: 194 DPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSR 253 Query: 332 DDSVGEATIPLDGVYTEGSIPPTVYNVVKDEEY----RGEIKIGLTFTPEEAR 478 DD +GE +PL GV +++K RGE+++ L++ P R Sbjct: 254 DDVIGEVMVPLAGVDPSTGKVQLTRDIIKRNIQKCISRGELQVSLSYQPVAQR 306
>YKH3_SCHPO (Q9UT00) Hypothetical protein PYUK71.03c in chromosome I| Length = 1225 Score = 35.4 bits (80), Expect = 0.13 Identities = 32/133 (24%), Positives = 57/133 (42%), Gaps = 1/133 (0%) Frame = +2 Query: 74 EIRPGEKMAQGTLEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKSTVASGKGSDPEWN 253 E+ E M + T++V + A L D DP+ V +E T + +P +N Sbjct: 1029 EVEMYENMGEMTVDV--IKATDLPAADSNGKSDPFVVFELQGEEVYRTKTHKRTLNPTFN 1086 Query: 254 ETF-VFTVSENARELVIKLLDSDGGTEDDSVGEATIPLDGVYTEGSIPPTVYNVVKDEEY 430 E+F V + V + D D G +DD +G I + + T Y + D + Sbjct: 1087 ESFEVELPCKQTCNFVANVFDWDFGNKDDHLGSCVIDCKLLQQQ---QQTNYEIPLDSK- 1142 Query: 431 RGEIKIGLTFTPE 469 +G + + +T +P+ Sbjct: 1143 QGVLYLRITLSPK 1155 Score = 35.4 bits (80), Expect = 0.13 Identities = 22/68 (32%), Positives = 37/68 (54%), Gaps = 2/68 (2%) Frame = +2 Query: 167 MDPYAVLRCTSQEQ--KSTVASGKGSDPEWNETFVFTVSENARELVIKLLDSDGGTEDDS 340 +DPY V++ ++ KS VA GS P +NETF ++ + L +++ D + D Sbjct: 455 VDPYVVIKNSADRVIGKSKVAHNTGS-PVFNETFYSVLNSFSENLNLEVYDFNDIRSDKL 513 Query: 341 VGEATIPL 364 +G A +PL Sbjct: 514 LGSAVLPL 521
>SYT11_HUMAN (Q9BT88) Synaptotagmin-11 (Synaptotagmin XI) (SytXI)| Length = 431 Score = 35.4 bits (80), Expect = 0.13 Identities = 30/113 (26%), Positives = 50/113 (44%), Gaps = 10/113 (8%) Frame = +2 Query: 170 DPYAVLRCTSQEQK--STVASGKGSDPEWNETFVF--TVSENARELVIK--LLDSDGGTE 331 DPY + ++ T K DP ++ETF F ++LV+ +L D + Sbjct: 195 DPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSR 254 Query: 332 DDSVGEATIPLDGVYTEGSIPPTVYNVVKDEEY----RGEIKIGLTFTPEEAR 478 DD +GE +PL GV +++K RGE+++ L++ P R Sbjct: 255 DDVIGEVMVPLAGVDPSTGKVQLTRDIIKRNIQKCISRGELQVSLSYQPVAQR 307
>UN13C_MOUSE (Q8K0T7) Unc-13 homolog C (Munc13-3) (Fragment)| Length = 1430 Score = 35.0 bits (79), Expect = 0.17 Identities = 16/70 (22%), Positives = 35/70 (50%) Frame = +2 Query: 110 LEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKSTVASGKGSDPEWNETFVFTVSENAR 289 + + +V A+GL+ D + DPY ++ ++++ G +P W+E F F + Sbjct: 1218 ITITVVSAQGLQAKDKTGSSDPYVTVQVGKNKRRTKTIFG-NLNPVWDEKFFFECHNSTD 1276 Query: 290 ELVIKLLDSD 319 + +++ D D Sbjct: 1277 RIKVRVWDED 1286
>UN13C_HUMAN (Q8NB66) Unc-13 homolog C (Munc13-3) (Fragment)| Length = 1190 Score = 35.0 bits (79), Expect = 0.17 Identities = 16/70 (22%), Positives = 35/70 (50%) Frame = +2 Query: 110 LEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKSTVASGKGSDPEWNETFVFTVSENAR 289 + + +V A+GL+ D + DPY ++ ++++ G +P W+E F F + Sbjct: 198 ITITVVSAQGLQAKDKTGSSDPYVTVQVGKNKRRTKTIFG-NLNPVWDEKFYFECHNSTD 256 Query: 290 ELVIKLLDSD 319 + +++ D D Sbjct: 257 RIKVRVWDED 266
>UN13C_RAT (Q62770) Unc-13 homolog C (Munc13-3)| Length = 2204 Score = 35.0 bits (79), Expect = 0.17 Identities = 16/70 (22%), Positives = 35/70 (50%) Frame = +2 Query: 110 LEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKSTVASGKGSDPEWNETFVFTVSENAR 289 + + +V A+GL+ D + DPY ++ ++++ G +P W+E F F + Sbjct: 1212 ITITVVSAQGLQAKDKTGSSDPYVTVQVGKNKRRTKTIFG-NLNPVWDEKFYFECHNSTD 1270 Query: 290 ELVIKLLDSD 319 + +++ D D Sbjct: 1271 RIKVRVWDED 1280
>PA24A_CHICK (P49147) Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group| IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase); Lysophospholipase (EC 3.1.1.5)] Length = 748 Score = 35.0 bits (79), Expect = 0.17 Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 2/76 (2%) Frame = +2 Query: 152 DYLCNMDPYAVLRCTSQE--QKSTVASGKGSDPEWNETFVFTVSENARELVIKLLDSDGG 325 D L DPY L S +K T +P WNETF F + N ++ L Sbjct: 37 DMLDTPDPYVELFIPSAPDCRKRTKHFNNDVNPVWNETFEFILDPNQDNVLEVTLMDANY 96 Query: 326 TEDDSVGEATIPLDGV 373 D+++G AT P+ + Sbjct: 97 VMDETLGMATFPISSL 112
>SYT2_HUMAN (Q8N9I0) Synaptotagmin-2 (Synaptotagmin II) (SytII)| Length = 419 Score = 35.0 bits (79), Expect = 0.17 Identities = 27/93 (29%), Positives = 43/93 (46%), Gaps = 5/93 (5%) Frame = +2 Query: 110 LEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKS--TVASGKGSDPEWNETFVFTVSEN 283 L V ++ A L D DPY + ++K T K +P +NETF F V Sbjct: 156 LTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQ 215 Query: 284 ---ARELVIKLLDSDGGTEDDSVGEATIPLDGV 373 + LV+ + D D ++ D +GE +P++ V Sbjct: 216 ELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTV 248
>EN16_STRPU (P13665) Protein ENDO16 (Fragment)| Length = 265 Score = 35.0 bits (79), Expect = 0.17 Identities = 32/114 (28%), Positives = 55/114 (48%), Gaps = 13/114 (11%) Frame = +2 Query: 197 SQEQKSTVASGKGSDPEWNETFVFTVSENARELVIKLLDSDGGTEDDSVGEATIPLDGVY 376 SQ Q+S + +GS+ E +E +E A E + ++S+GG +++S G A P + + Sbjct: 101 SQGQESERSESEGSEGEDSEE-----TEGAEE-PHEQMESEGGDQEESEG-AEQPQEQME 153 Query: 377 TEGSIPPTVYNVVKDE-------------EYRGEIKIGLTFTPEEARDEDQPEE 499 +EG P + +V E G + +GLT E+ D ++PEE Sbjct: 154 SEGQEPESEEDVDSGEITDGSDMNMPGPGSSDGGVPLGLTEVDEQTSDGEEPEE 207
>SYT2_RAT (P29101) Synaptotagmin-2 (Synaptotagmin II) (SytII)| Length = 422 Score = 35.0 bits (79), Expect = 0.17 Identities = 27/93 (29%), Positives = 43/93 (46%), Gaps = 5/93 (5%) Frame = +2 Query: 110 LEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKS--TVASGKGSDPEWNETFVFTVSEN 283 L V ++ A L D DPY + ++K T K +P +NETF F V Sbjct: 159 LTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQ 218 Query: 284 ---ARELVIKLLDSDGGTEDDSVGEATIPLDGV 373 + LV+ + D D ++ D +GE +P++ V Sbjct: 219 ELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTV 251
>SYT2_MOUSE (P46097) Synaptotagmin-2 (Synaptotagmin II) (SytII)| Length = 422 Score = 35.0 bits (79), Expect = 0.17 Identities = 27/93 (29%), Positives = 43/93 (46%), Gaps = 5/93 (5%) Frame = +2 Query: 110 LEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKS--TVASGKGSDPEWNETFVFTVSEN 283 L V ++ A L D DPY + ++K T K +P +NETF F V Sbjct: 159 LTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQ 218 Query: 284 ---ARELVIKLLDSDGGTEDDSVGEATIPLDGV 373 + LV+ + D D ++ D +GE +P++ V Sbjct: 219 ELAGKTLVMAIYDFDRFSKHDIIGEVKVPMNTV 251
>RASA2_HUMAN (Q15283) Ras GTPase-activating protein 2 (GAP1m)| Length = 849 Score = 34.7 bits (78), Expect = 0.22 Identities = 33/140 (23%), Positives = 57/140 (40%), Gaps = 27/140 (19%) Frame = +2 Query: 170 DPYAVLRCTS---QEQKSTVASGKGSDPEWNETFVFTVSENAR----------------- 289 DPYA + +QK T K S+P++NE F F V+ ++ Sbjct: 192 DPYATVSLVGPSRNDQKKTKVKKKTSNPQFNEIFYFEVTRSSSYTRKSQFQVEEEDIEKL 251 Query: 290 ELVIKLLDSDGGTEDDSVGEATIPLDGVYTEGS-------IPPTVYNVVKDEEYRGEIKI 448 E+ I L ++ +D +GE +P++ + T+ S P N + G +++ Sbjct: 252 EIRIDLWNNGNLVQDVFLGEIKVPVNVLRTDSSHQAWYLLQPRDNGNKSSKTDDLGSLRL 311 Query: 449 GLTFTPEEARDEDQPEENYG 508 + +T D P E YG Sbjct: 312 NICYT----EDYVLPSEYYG 327
>PLDB2_ARATH (O23078) Phospholipase D beta 2 (EC 3.1.4.4) (AtPLDbeta2) (PLD beta| 2) (PLDdelta1) Length = 915 Score = 34.7 bits (78), Expect = 0.22 Identities = 28/120 (23%), Positives = 44/120 (36%), Gaps = 2/120 (1%) Frame = +2 Query: 47 HLRSWVGEGEIRPGEKMAQGTLEVLLVGAKGL--ENTDYLCNMDPYAVLRCTSQEQKSTV 220 +L WV P + TL V+ G + DPY + T Sbjct: 118 NLDIWVSCANNLPNLDLFHKTLGVVFGGMTNMIEGQLSKKITSDPYVSISVAGAVIGRTY 177 Query: 221 ASGKGSDPEWNETFVFTVSENARELVIKLLDSDGGTEDDSVGEATIPLDGVYTEGSIPPT 400 +P W + F V+ +A E+ + DSD +G TIP++ +Y+ I T Sbjct: 178 VISNSENPVWQQHFYVPVAHHAAEVHFVVKDSD-AVGSQLIGIVTIPVEQIYSGARIEGT 236
>UN13D_HUMAN (Q70J99) Unc-13 homolog D (Munc13-4)| Length = 1090 Score = 34.7 bits (78), Expect = 0.22 Identities = 35/130 (26%), Positives = 56/130 (43%), Gaps = 17/130 (13%) Frame = +2 Query: 62 VGEGEIRPGEKMAQGTLEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQ------KSTVA 223 +G ++ + ++ L V L+ A L D + DP+ L + + + T Sbjct: 911 LGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFPELAARETQK 970 Query: 224 SGKGSDPEWNETFVFTV-SENARE----LVIKLLDSDGGTEDDSVGEATIP------LDG 370 K P ++ETF F V +E R+ L++ +LD D DD GEA +P L G Sbjct: 971 HKKDLHPLFDETFEFLVPAEPCRKAGACLLLTVLDYDTLGADDLEGEAFLPLREVPGLSG 1030 Query: 371 VYTEGSIPPT 400 G +P T Sbjct: 1031 SEEPGEVPQT 1040
>UN13A_HUMAN (Q9UPW8) Unc-13 homolog A (Munc13-1)| Length = 1703 Score = 34.3 bits (77), Expect = 0.29 Identities = 24/85 (28%), Positives = 39/85 (45%) Frame = +2 Query: 110 LEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKSTVASGKGSDPEWNETFVFTVSENAR 289 + +L VG K + + Y L+ Q KST + +GS P W + F+F ++ Sbjct: 1 MSLLCVGVKKAKFDGAQEKFNTYVTLKV--QNVKSTTIAVRGSQPSWEQDFMFEINRLDL 58 Query: 290 ELVIKLLDSDGGTEDDSVGEATIPL 364 L +++ + G D VG IPL Sbjct: 59 GLTVEVWNK-GLIWDTMVGTVWIPL 82 Score = 33.5 bits (75), Expect = 0.50 Identities = 16/70 (22%), Positives = 35/70 (50%) Frame = +2 Query: 110 LEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKSTVASGKGSDPEWNETFVFTVSENAR 289 + + +V A+GL+ D + DPY ++ ++++ G +P W E F F ++ Sbjct: 678 ISITVVCAQGLQAKDKTGSSDPYVTVQVGKTKKRTKTIYG-NLNPVWEENFHFECHNSSD 736 Query: 290 ELVIKLLDSD 319 + +++ D D Sbjct: 737 RIKVRVWDED 746
>UN13B_HUMAN (O14795) Unc-13 homolog B (Munc13-2) (munc13)| Length = 1591 Score = 33.9 bits (76), Expect = 0.38 Identities = 16/70 (22%), Positives = 36/70 (51%) Frame = +2 Query: 110 LEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKSTVASGKGSDPEWNETFVFTVSENAR 289 + + +V A+GL+ D + DPY ++ + ++++ G +P W E F F ++ Sbjct: 602 ITITVVCAQGLQAKDKTGSSDPYVTVQVSKTKKRTKTIFG-NLNPVWEEKFHFECHNSSD 660 Query: 290 ELVIKLLDSD 319 + +++ D D Sbjct: 661 RIKVRVWDED 670 Score = 30.0 bits (66), Expect = 5.5 Identities = 29/114 (25%), Positives = 46/114 (40%), Gaps = 9/114 (7%) Frame = +2 Query: 200 QEQKSTVASGKGSDPEWNETFVFTVSENARELVIKLLDSDGGTEDDSVGEATIPLDGVYT 379 Q KST + +G P W + F+F +S L +++ + G D VG I L + Sbjct: 29 QNVKSTTVAVRGDQPSWEQDFMFEISRLDLGLSVEVWNK-GLIWDTMVGTVWIALKTIRQ 87 Query: 380 EGSIPPTVYNVVKDEEYRGEIKIGLTFTPE------EARDE---DQPEENYGGW 514 P ++ ++ E + +I T P + R E D PEE W Sbjct: 88 SDEEGPGEWSTLEAETLMKDDEICGTRNPTPHKILLDTRFELPFDIPEEEARYW 141
>DOC2A_HUMAN (Q14183) Double C2-like domain-containing protein alpha| (Doc2-alpha) (Doc2) Length = 400 Score = 33.9 bits (76), Expect = 0.38 Identities = 27/98 (27%), Positives = 47/98 (47%), Gaps = 9/98 (9%) Frame = +2 Query: 98 AQGTLEVLLVGAKGLENTDYLCNMDPYAVLR-----CTSQEQKSTVASGKGSDPEWNETF 262 A TL ++ AKGL+ D+ DPY L C + + K T +P WNE Sbjct: 102 ASCTLHCSILRAKGLKPMDFNGLADPYVKLHLLPGACKANKLK-TKTQRNTLNPVWNEDL 160 Query: 263 VFT-VSEN---ARELVIKLLDSDGGTEDDSVGEATIPL 364 ++ ++++ + L I + D D + ++ +GE +PL Sbjct: 161 TYSGITDDDITHKVLRIAVCDEDKLSHNEFIGEIRVPL 198
>PA24A_BRARE (P50392) Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group| IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase); Lysophospholipase (EC 3.1.1.5)] Length = 741 Score = 33.9 bits (76), Expect = 0.38 Identities = 22/73 (30%), Positives = 32/73 (43%), Gaps = 2/73 (2%) Frame = +2 Query: 152 DYLCNMDPYAVLRC--TSQEQKSTVASGKGSDPEWNETFVFTVSENARELVIKLLDSDGG 325 D L DPY L T + +K T +P+WNETF F + N ++ L Sbjct: 31 DLLDTPDPYVELSVPTTPESRKRTRHINNDINPKWNETFEFILDPNQSNVLEVTLMDANY 90 Query: 326 TEDDSVGEATIPL 364 D+++G A L Sbjct: 91 VMDETLGTAKYSL 103
>SUDX_DROME (Q9Y0H4) E3 ubiquitin-protein ligase suppressor of deltex (EC| 6.3.2.-) Length = 949 Score = 33.9 bits (76), Expect = 0.38 Identities = 23/75 (30%), Positives = 35/75 (46%) Frame = +2 Query: 140 LENTDYLCNMDPYAVLRCTSQEQKSTVASGKGSDPEWNETFVFTVSENARELVIKLLDSD 319 L N +L +PY L S+ ++ T P+WNE F ++ N+ L K+LD Sbjct: 60 LRNNGFL-KPNPYVELLIDSKSKRKTDLVKNSYLPKWNEEFTVLITPNS-TLHFKVLDHS 117 Query: 320 GGTEDDSVGEATIPL 364 +D +GE I L Sbjct: 118 SFRKDAMLGERIINL 132
>SYT4_RAT (P50232) Synaptotagmin-4 (Synaptotagmin IV) (SytIV)| Length = 425 Score = 33.5 bits (75), Expect = 0.50 Identities = 29/107 (27%), Positives = 50/107 (46%), Gaps = 10/107 (9%) Frame = +2 Query: 170 DPYAVLRCTSQEQKS--TVASGKGSDPEWNETFVF--TVSENARELVIK--LLDSDGGTE 331 DPY + +++ T K DP ++ETF F + +EL + +L D + Sbjct: 191 DPYIKMTILPEKKHKVKTRVLRKTLDPVFDETFTFYGVPYPHIQELSLHFTVLSFDRFSR 250 Query: 332 DDSVGEATIPLDGV-YTEGSIPPT---VYNVVKDEEYRGEIKIGLTF 460 DD +GE +PL G+ ++G + T + K RGE+ + L + Sbjct: 251 DDVIGEVLVPLSGIELSDGKMLMTREIIKRNAKKSSGRGELLVSLCY 297
>SYT4_MOUSE (P40749) Synaptotagmin-4 (Synaptotagmin IV) (SytIV)| Length = 425 Score = 33.5 bits (75), Expect = 0.50 Identities = 30/107 (28%), Positives = 50/107 (46%), Gaps = 10/107 (9%) Frame = +2 Query: 170 DPYAVLRCTSQEQK--STVASGKGSDPEWNETFVF--TVSENARELVIK--LLDSDGGTE 331 DPY + +++ T K DP ++ETF F + +EL + +L D + Sbjct: 191 DPYIKMTILPEKKHRVKTRVLRKTLDPVFDETFTFYGIPYPHIQELSLHFTVLSFDRFSR 250 Query: 332 DDSVGEATIPLDGV-YTEGSIPPT---VYNVVKDEEYRGEIKIGLTF 460 DD +GE IPL G+ ++G + T + K RGE+ + L + Sbjct: 251 DDVIGEVLIPLSGIELSDGKMLMTREIIKRNAKKSSGRGELLVSLCY 297
>RASA2_RAT (Q63713) Ras GTPase-activating protein 2 (GAP1m)| Length = 847 Score = 33.5 bits (75), Expect = 0.50 Identities = 23/93 (24%), Positives = 42/93 (45%), Gaps = 20/93 (21%) Frame = +2 Query: 170 DPYAVLRCTS---QEQKSTVASGKGSDPEWNETFVFTVSENAR----------------- 289 DPYA + +QK T K S+P++NE F F V+ ++ Sbjct: 191 DPYATVSLVGPSRNDQKKTKVKKKTSNPQFNEVFYFEVTRSSSYTRKSQFQVEEEDIEKL 250 Query: 290 ELVIKLLDSDGGTEDDSVGEATIPLDGVYTEGS 388 E+ I L +++ +D +GE +P++ + + S Sbjct: 251 EIRIDLWNNENLVQDVFLGEIKVPVNVLRNDSS 283
>KPCG_RAT (P63319) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 33.5 bits (75), Expect = 0.50 Identities = 26/86 (30%), Positives = 41/86 (47%), Gaps = 17/86 (19%) Frame = +2 Query: 170 DPYAVLRC-------TSQEQKSTVASGKGSDPEWNETFVFTV--SENARELVIKLLDSDG 322 DPY L+ T Q+ K+ A+ +P WNETFVF + + R L +++ D D Sbjct: 193 DPYVKLKLIPDPRNLTKQKTKTVKAT---LNPVWNETFVFNLKPGDVERRLSVEVWDWDR 249 Query: 323 GTEDDSVGEATI--------PLDGVY 376 + +D +G + P+DG Y Sbjct: 250 TSRNDFMGAMSFGVSELLKAPVDGWY 275
>KPCG_MOUSE (P63318) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 33.5 bits (75), Expect = 0.50 Identities = 26/86 (30%), Positives = 41/86 (47%), Gaps = 17/86 (19%) Frame = +2 Query: 170 DPYAVLRC-------TSQEQKSTVASGKGSDPEWNETFVFTV--SENARELVIKLLDSDG 322 DPY L+ T Q+ K+ A+ +P WNETFVF + + R L +++ D D Sbjct: 193 DPYVKLKLIPDPRNLTKQKTKTVKAT---LNPVWNETFVFNLKPGDVERRLSVEVWDWDR 249 Query: 323 GTEDDSVGEATI--------PLDGVY 376 + +D +G + P+DG Y Sbjct: 250 TSRNDFMGAMSFGVSELLKAPVDGWY 275
>YC31_SCHPO (O14065) Hypothetical protein C962.01 in chromosome III| Length = 1429 Score = 33.5 bits (75), Expect = 0.50 Identities = 32/124 (25%), Positives = 50/124 (40%), Gaps = 3/124 (2%) Frame = +2 Query: 104 GTLEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKSTVASGKGSDPEWNETFVFTVSEN 283 G+L +L + L D + + DP+ VL+ + + K +P WNE V Sbjct: 1078 GSLHFMLQDGQNLPIGD-IRSSDPFVVLKLNGESAFKSKVIKKNLNPVWNEEADIVVQNR 1136 Query: 284 ARE-LVIKLLDSDGGTEDDSVGEATIPLDGVYTEGSIPPTV--YNVVKDEEYRGEIKIGL 454 + L + D D G + D +G + I L S+ P V +K + G I L Sbjct: 1137 VLDVLELVCYDWDMGEKPDVLGTSNIDL------LSLEPNVESQQSIKLDSKTGTINASL 1190 Query: 455 TFTP 466 F P Sbjct: 1191 RFVP 1194 Score = 32.3 bits (72), Expect = 1.1 Identities = 20/86 (23%), Positives = 39/86 (45%), Gaps = 1/86 (1%) Frame = +2 Query: 104 GTLEVLLVGAKGLENTDYLCNM-DPYAVLRCTSQEQKSTVASGKGSDPEWNETFVFTVSE 280 G + + ++ A L N + DPYA + + TV + +P WNE + Sbjct: 757 GVMRLSVIKANDLVNVELPTRKSDPYARVIVGNSVVARTVYTPNNLNPIWNEILYVPIMA 816 Query: 281 NARELVIKLLDSDGGTEDDSVGEATI 358 + + + ++ +D + D S+G A+I Sbjct: 817 DTKTIDLEAMDYEESGNDRSLGYASI 842
>PLDB1_ARATH (P93733) Phospholipase D beta 1 (EC 3.1.4.4) (AtPLDbeta1) (PLD beta| 1) (PLDbeta) Length = 967 Score = 33.5 bits (75), Expect = 0.50 Identities = 27/124 (21%), Positives = 44/124 (35%), Gaps = 22/124 (17%) Frame = +2 Query: 95 MAQGTLEVLLVGAKGLENTDYL----------------------CNMDPYAVLRCTSQEQ 208 ++ G L++ + AK L N D DPY + Sbjct: 153 LSHGNLDIWIYHAKNLPNMDMFHKTLGDMFGRLPGKIEGQLTSKITSDPYVSVSVAGAVI 212 Query: 209 KSTVASGKGSDPEWNETFVFTVSENARELVIKLLDSDGGTEDDSVGEATIPLDGVYTEGS 388 T +P W + F V+ +A E+ + DSD +G TIP++ +Y+ Sbjct: 213 GRTYVMSNSENPVWMQHFYVPVAHHAAEVHFVVKDSD-VVGSQLIGLVTIPVEQIYSGAK 271 Query: 389 IPPT 400 I T Sbjct: 272 IEGT 275
>PLCD1_HUMAN (P51178) 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase| delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III) Length = 756 Score = 33.5 bits (75), Expect = 0.50 Identities = 17/57 (29%), Positives = 33/57 (57%), Gaps = 1/57 (1%) Frame = +2 Query: 206 QKSTVASGKGSDPEWNETFVFTVSENARELVIKLL-DSDGGTEDDSVGEATIPLDGV 373 +++ V + G +P W+ F F V L+ L+ D D +++D +G++TIPL+ + Sbjct: 670 RQTAVITNNGFNPWWDTEFAFEVVVPDLALIRFLVEDYDASSKNDFIGQSTIPLNSL 726
>KPCE_RAT (P09216) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 737 Score = 33.1 bits (74), Expect = 0.65 Identities = 20/74 (27%), Positives = 30/74 (40%) Frame = +2 Query: 167 MDPYAVLRCTSQEQKSTVASGKGSDPEWNETFVFTVSENARELVIKLLDSDGGTEDDSVG 346 +DPY L T K + P W++ FV V N R++ + + DD V Sbjct: 38 LDPYIALNVDDSRIGQTATKQKTNSPAWHDEFVTDVC-NGRKIELAVFHDAPIGYDDFVA 96 Query: 347 EATIPLDGVYTEGS 388 TI + + GS Sbjct: 97 NCTIQFEELLQNGS 110
>KPCE_MOUSE (P16054) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 737 Score = 33.1 bits (74), Expect = 0.65 Identities = 20/74 (27%), Positives = 30/74 (40%) Frame = +2 Query: 167 MDPYAVLRCTSQEQKSTVASGKGSDPEWNETFVFTVSENARELVIKLLDSDGGTEDDSVG 346 +DPY L T K + P W++ FV V N R++ + + DD V Sbjct: 38 LDPYIALNVDDSRIGQTATKQKTNSPAWHDEFVTDVC-NGRKIELAVFHDAPIGYDDFVA 96 Query: 347 EATIPLDGVYTEGS 388 TI + + GS Sbjct: 97 NCTIQFEELLQNGS 110
>KPCE_HUMAN (Q02156) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 737 Score = 33.1 bits (74), Expect = 0.65 Identities = 20/74 (27%), Positives = 30/74 (40%) Frame = +2 Query: 167 MDPYAVLRCTSQEQKSTVASGKGSDPEWNETFVFTVSENARELVIKLLDSDGGTEDDSVG 346 +DPY L T K + P W++ FV V N R++ + + DD V Sbjct: 38 LDPYIALNVDDSRIGQTATKQKTNSPAWHDEFVTDVC-NGRKIELAVFHDAPIGYDDFVA 96 Query: 347 EATIPLDGVYTEGS 388 TI + + GS Sbjct: 97 NCTIQFEELLQNGS 110
>KPCE_RABIT (P10830) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 736 Score = 33.1 bits (74), Expect = 0.65 Identities = 20/74 (27%), Positives = 30/74 (40%) Frame = +2 Query: 167 MDPYAVLRCTSQEQKSTVASGKGSDPEWNETFVFTVSENARELVIKLLDSDGGTEDDSVG 346 +DPY L T K + P W++ FV V N R++ + + DD V Sbjct: 38 LDPYIALNVDDSRIGQTATKQKTNSPAWHDEFVTDVC-NGRKIELAVFHDAPIGYDDFVA 96 Query: 347 EATIPLDGVYTEGS 388 TI + + GS Sbjct: 97 NCTIQFEELLQNGS 110
>UN13D_RAT (Q9R189) Unc-13 homolog D (Munc13-4)| Length = 1088 Score = 32.7 bits (73), Expect = 0.85 Identities = 29/112 (25%), Positives = 49/112 (43%), Gaps = 11/112 (9%) Frame = +2 Query: 62 VGEGEIRPGEKMAQGTLEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQ------KSTVA 223 +G ++ + ++ L V L+ A L D + DP+ L + + + T Sbjct: 909 LGAVTVKASYRASEQKLHVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFPELAPRETQK 968 Query: 224 SGKGSDPEWNETFVFTV-----SENARELVIKLLDSDGGTEDDSVGEATIPL 364 K P ++ETF F V ++ L++ +LD D DD GEA +PL Sbjct: 969 HKKELHPLFDETFEFLVPAEPCQKDGACLLLTVLDHDRLGADDLEGEAFLPL 1020
>RASA2_MOUSE (P58069) Ras GTPase-activating protein 2 (GAP1m)| Length = 848 Score = 32.7 bits (73), Expect = 0.85 Identities = 22/86 (25%), Positives = 39/86 (45%), Gaps = 20/86 (23%) Frame = +2 Query: 170 DPYAVLRCTS---QEQKSTVASGKGSDPEWNETFVFTVSENAR----------------- 289 DPYA + +QK T K S+P++NE F F V+ ++ Sbjct: 192 DPYATVSLVGPSRNDQKKTKVKKKTSNPQFNEVFYFEVTRSSSYSRKSQFQVEEEDIEKL 251 Query: 290 ELVIKLLDSDGGTEDDSVGEATIPLD 367 E+ I L +++ +D +GE +P++ Sbjct: 252 EIRIDLWNNENLVQDVFLGEIKVPVN 277
>KPC2_DROME (P13677) Protein kinase C, eye isozyme (EC 2.7.11.13) (PKC)| (dPKC53E(EY)) (Protein INAC) (Inactivation no after-potential C protein) (Photoreceptor-specific PKC) (Eye-PKC) Length = 700 Score = 32.7 bits (73), Expect = 0.85 Identities = 21/77 (27%), Positives = 39/77 (50%), Gaps = 6/77 (7%) Frame = +2 Query: 170 DPYAVLRC----TSQEQKSTVASGKGSDPEWNETFVFTVSENARE--LVIKLLDSDGGTE 331 DPY ++ + + +K T K +P +NETF F + R+ L+I++ D D + Sbjct: 228 DPYIAVQMHPDRSGRTKKKTKTIQKNLNPVFNETFTFELQPQDRDKRLLIEVWDWDRTSR 287 Query: 332 DDSVGEATIPLDGVYTE 382 +D +G + L+ + E Sbjct: 288 NDFMGSFSFSLEELQKE 304
>UN13B_MOUSE (Q9Z1N9) Unc-13 homolog B (Munc13-2) (munc13)| Length = 1591 Score = 32.7 bits (73), Expect = 0.85 Identities = 16/70 (22%), Positives = 35/70 (50%) Frame = +2 Query: 110 LEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKSTVASGKGSDPEWNETFVFTVSENAR 289 + + +V A+GL+ D + DPY ++ ++++ G +P W E F F ++ Sbjct: 602 ITITVVCAQGLQAKDKTGSSDPYVTVQVGKTKKRTKTIFG-NLNPVWEEKFHFECHNSSD 660 Query: 290 ELVIKLLDSD 319 + +++ D D Sbjct: 661 RIKVRVWDED 670 Score = 31.6 bits (70), Expect = 1.9 Identities = 29/114 (25%), Positives = 47/114 (41%), Gaps = 9/114 (7%) Frame = +2 Query: 200 QEQKSTVASGKGSDPEWNETFVFTVSENARELVIKLLDSDGGTEDDSVGEATIPLDGVYT 379 Q +KST + +G P W + F+F +S L +++ + G D VG I L + Sbjct: 29 QNEKSTTVAVRGDQPSWEQDFMFEISRLDLGLSVEVWNK-GLIWDTMVGTVWIALKTIRQ 87 Query: 380 EGSIPPTVYNVVKDEEYRGEIKIGLTFTPE------EARDE---DQPEENYGGW 514 P ++ ++ E + +I T P + R E D PEE W Sbjct: 88 SDEEGPGEWSTLEAETLMKDDEICGTKNPTPHKILLDTRFELPFDIPEEEARYW 141
>SYT1_PONPY (Q5R4J5) Synaptotagmin-1 (Synaptotagmin I) (SytI)| Length = 419 Score = 32.7 bits (73), Expect = 0.85 Identities = 34/121 (28%), Positives = 52/121 (42%), Gaps = 18/121 (14%) Frame = +2 Query: 65 GEGEIRPGEKMAQGTLEV----------LLVG---AKGLENTDYLCNMDPYAVLRCTSQE 205 GE + P E+ G L+ LLVG A L D DPY + + Sbjct: 128 GEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDK 187 Query: 206 QKS--TVASGKGSDPEWNETFVFTVSEN---ARELVIKLLDSDGGTEDDSVGEATIPLDG 370 +K T K +P +NE F F V + + LV+ + D D ++ D +GE +P++ Sbjct: 188 KKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNT 247 Query: 371 V 373 V Sbjct: 248 V 248
>SYT1_MACFA (Q60HC0) Synaptotagmin-1 (Synaptotagmin I) (SytI)| Length = 419 Score = 32.7 bits (73), Expect = 0.85 Identities = 34/121 (28%), Positives = 52/121 (42%), Gaps = 18/121 (14%) Frame = +2 Query: 65 GEGEIRPGEKMAQGTLEV----------LLVG---AKGLENTDYLCNMDPYAVLRCTSQE 205 GE + P E+ G L+ LLVG A L D DPY + + Sbjct: 128 GEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDK 187 Query: 206 QKS--TVASGKGSDPEWNETFVFTVSEN---ARELVIKLLDSDGGTEDDSVGEATIPLDG 370 +K T K +P +NE F F V + + LV+ + D D ++ D +GE +P++ Sbjct: 188 KKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNT 247 Query: 371 V 373 V Sbjct: 248 V 248
>UN13B_RAT (Q62769) Unc-13 homolog B (Munc13-2)| Length = 1622 Score = 32.7 bits (73), Expect = 0.85 Identities = 16/70 (22%), Positives = 35/70 (50%) Frame = +2 Query: 110 LEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKSTVASGKGSDPEWNETFVFTVSENAR 289 + + +V A+GL+ D + DPY ++ ++++ G +P W E F F ++ Sbjct: 615 ITITVVCAQGLQAKDKTGSSDPYVTVQVGKTKKRTKTIFG-NLNPVWEEKFHFECHNSSD 673 Query: 290 ELVIKLLDSD 319 + +++ D D Sbjct: 674 RIKVRVWDED 683 Score = 29.3 bits (64), Expect = 9.4 Identities = 19/75 (25%), Positives = 33/75 (44%) Frame = +2 Query: 200 QEQKSTVASGKGSDPEWNETFVFTVSENARELVIKLLDSDGGTEDDSVGEATIPLDGVYT 379 Q KST + +G P W + F+F +S L +++ + G D VG I L + Sbjct: 29 QNVKSTTVAVRGDQPSWEQDFMFEISRLDLGLSVEVWNK-GLIWDTMVGTVWIALKTIRQ 87 Query: 380 EGSIPPTVYNVVKDE 424 P ++ ++ E Sbjct: 88 SDEEGPGEWSTLEAE 102
>SYT1_RAT (P21707) Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65)| Length = 421 Score = 32.7 bits (73), Expect = 0.85 Identities = 34/121 (28%), Positives = 52/121 (42%), Gaps = 18/121 (14%) Frame = +2 Query: 65 GEGEIRPGEKMAQGTLEV----------LLVG---AKGLENTDYLCNMDPYAVLRCTSQE 205 GE + P E+ G L+ LLVG A L D DPY + + Sbjct: 130 GEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDK 189 Query: 206 QKS--TVASGKGSDPEWNETFVFTVSEN---ARELVIKLLDSDGGTEDDSVGEATIPLDG 370 +K T K +P +NE F F V + + LV+ + D D ++ D +GE +P++ Sbjct: 190 KKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNT 249 Query: 371 V 373 V Sbjct: 250 V 250
>SYT1_MOUSE (P46096) Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65)| Length = 421 Score = 32.7 bits (73), Expect = 0.85 Identities = 34/121 (28%), Positives = 52/121 (42%), Gaps = 18/121 (14%) Frame = +2 Query: 65 GEGEIRPGEKMAQGTLEV----------LLVG---AKGLENTDYLCNMDPYAVLRCTSQE 205 GE + P E+ G L+ LLVG A L D DPY + + Sbjct: 130 GEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDK 189 Query: 206 QKS--TVASGKGSDPEWNETFVFTVSEN---ARELVIKLLDSDGGTEDDSVGEATIPLDG 370 +K T K +P +NE F F V + + LV+ + D D ++ D +GE +P++ Sbjct: 190 KKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNT 249 Query: 371 V 373 V Sbjct: 250 V 250
>SYT1_HUMAN (P21579) Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65)| Length = 422 Score = 32.7 bits (73), Expect = 0.85 Identities = 34/121 (28%), Positives = 52/121 (42%), Gaps = 18/121 (14%) Frame = +2 Query: 65 GEGEIRPGEKMAQGTLEV----------LLVG---AKGLENTDYLCNMDPYAVLRCTSQE 205 GE + P E+ G L+ LLVG A L D DPY + + Sbjct: 131 GEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDK 190 Query: 206 QKS--TVASGKGSDPEWNETFVFTVSEN---ARELVIKLLDSDGGTEDDSVGEATIPLDG 370 +K T K +P +NE F F V + + LV+ + D D ++ D +GE +P++ Sbjct: 191 KKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNT 250 Query: 371 V 373 V Sbjct: 251 V 251
>SYT1_BOVIN (P48018) Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65)| Length = 422 Score = 32.7 bits (73), Expect = 0.85 Identities = 34/121 (28%), Positives = 52/121 (42%), Gaps = 18/121 (14%) Frame = +2 Query: 65 GEGEIRPGEKMAQGTLEV----------LLVG---AKGLENTDYLCNMDPYAVLRCTSQE 205 GE + P E+ G L+ LLVG A L D DPY + + Sbjct: 131 GEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDK 190 Query: 206 QKS--TVASGKGSDPEWNETFVFTVSEN---ARELVIKLLDSDGGTEDDSVGEATIPLDG 370 +K T K +P +NE F F V + + LV+ + D D ++ D +GE +P++ Sbjct: 191 KKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNT 250 Query: 371 V 373 V Sbjct: 251 V 251
>RP3A_HUMAN (Q9Y2J0) Rabphilin-3A (Exophilin-1)| Length = 694 Score = 32.3 bits (72), Expect = 1.1 Identities = 28/94 (29%), Positives = 41/94 (43%), Gaps = 8/94 (8%) Frame = +2 Query: 107 TLEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKS----TVASGKGSDPEWNETFVF-- 268 +L+ ++ AKGL+ D DPY L KS T +P WNET V+ Sbjct: 408 SLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHG 467 Query: 269 -TVSENARE-LVIKLLDSDGGTEDDSVGEATIPL 364 T + R+ L I + D D ++ +GE L Sbjct: 468 ITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSL 501
>KPCG_BOVIN (P05128) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| (Fragment) Length = 682 Score = 32.3 bits (72), Expect = 1.1 Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 17/86 (19%) Frame = +2 Query: 170 DPYAVLRC-------TSQEQKSTVASGKGSDPEWNETFVFTV--SENARELVIKLLDSDG 322 DPY L+ T Q+ ++ A+ +P WNETFVF + + R L +++ D D Sbjct: 178 DPYVKLKLIPDPRNLTKQKTRTVKAT---LNPVWNETFVFNLKPGDVERRLSVEVWDWDR 234 Query: 323 GTEDDSVGEATI--------PLDGVY 376 + +D +G + P+DG Y Sbjct: 235 TSRNDFMGAMSFGVSELLKAPVDGWY 260
>KPCG_RABIT (P10829) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| (PKC-delta) Length = 697 Score = 32.3 bits (72), Expect = 1.1 Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 17/86 (19%) Frame = +2 Query: 170 DPYAVLRC-------TSQEQKSTVASGKGSDPEWNETFVFTV--SENARELVIKLLDSDG 322 DPY L+ T Q+ ++ A+ +P WNETFVF + + R L +++ D D Sbjct: 193 DPYVKLKLIPDPRNLTKQKTRTVKAT---LNPVWNETFVFNLKPGDVERRLSVEVWDWDR 249 Query: 323 GTEDDSVGEATI--------PLDGVY 376 + +D +G + P+DG Y Sbjct: 250 TSRNDFMGAMSFGVSELLKAPVDGWY 275
>KPCG_HUMAN (P05129) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 32.3 bits (72), Expect = 1.1 Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 17/86 (19%) Frame = +2 Query: 170 DPYAVLRC-------TSQEQKSTVASGKGSDPEWNETFVFTV--SENARELVIKLLDSDG 322 DPY L+ T Q+ ++ A+ +P WNETFVF + + R L +++ D D Sbjct: 193 DPYVKLKLIPDPRNLTKQKTRTVKAT---LNPVWNETFVFNLKPGDVERRLSVEVWDWDR 249 Query: 323 GTEDDSVGEATI--------PLDGVY 376 + +D +G + P+DG Y Sbjct: 250 TSRNDFMGAMSFGVSELLKAPVDGWY 275
>SYTL5_MOUSE (Q80T23) Synaptotagmin-like protein 5| Length = 753 Score = 32.3 bits (72), Expect = 1.1 Identities = 27/102 (26%), Positives = 41/102 (40%), Gaps = 10/102 (9%) Frame = +2 Query: 197 SQEQKSTVASGKGSDPEWNETFVFTVSE---NARELVIKLLDSDGGTEDDSVGEATIPLD 367 S+ K G++PE+NET +T+S R L + + D + +GE I D Sbjct: 479 SRNNKRKTKIRTGTNPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIAFD 538 Query: 368 GVYTEGSIPPTVYNVVKDE-------EYRGEIKIGLTFTPEE 472 E K E +Y+GE+ I L + P E Sbjct: 539 SWNFENPCDEWFVLQPKVELAPDISLQYKGELTIVLRYIPPE 580 Score = 29.6 bits (65), Expect = 7.2 Identities = 19/71 (26%), Positives = 30/71 (42%), Gaps = 4/71 (5%) Frame = +2 Query: 71 GEIRPGEKMAQGTLEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKST----VASGKGS 238 G+ + ++ G LEV + AK L D + + K+T K Sbjct: 599 GKKKESSSISGGILEVFIKKAKNLTAVKSGGTSDSFVKGYLLPDDNKATKHKTAVVKKSV 658 Query: 239 DPEWNETFVFT 271 +PEWN TF+F+ Sbjct: 659 NPEWNHTFIFS 669
>SY62_DISOM (P24506) Synaptotagmin B (Synaptic vesicle protein O-p65-B)| Length = 439 Score = 32.0 bits (71), Expect = 1.4 Identities = 24/88 (27%), Positives = 41/88 (46%), Gaps = 5/88 (5%) Frame = +2 Query: 110 LEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKS--TVASGKGSDPEWNETFVFTV--- 274 L V ++ A L D DPY + ++K T K +P +NE+FVF V Sbjct: 176 LTVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVQKKTLNPTFNESFVFKVPYQ 235 Query: 275 SENARELVIKLLDSDGGTEDDSVGEATI 358 + L++ + D D ++ D +G+ T+ Sbjct: 236 ELGGKTLMMAVYDFDRFSKHDCIGQVTV 263
>PCLO_CHICK (Q9PU36) Protein piccolo (Aczonin) (Fragment)| Length = 5120 Score = 32.0 bits (71), Expect = 1.4 Identities = 27/120 (22%), Positives = 50/120 (41%), Gaps = 17/120 (14%) Frame = +2 Query: 65 GEGEIRPGEKMAQGTLEVLLVGAKGLENTDYLCNMDPYA-------------VLRCTSQE 205 GE +++ G L + ++ A+ L D DP+ V +++ Sbjct: 4613 GEIQLQINYDKHLGNLIIHILQARNLAPRDNNGYSDPFVKVYLLPGRGQVMVVQNASAEY 4672 Query: 206 QKSTVASGKGSDPEWNETFVF----TVSENARELVIKLLDSDGGTEDDSVGEATIPLDGV 373 ++ T K +PEWN+T ++ T + L + + D D + +D +GE I L V Sbjct: 4673 KRRTKYVQKSLNPEWNQTVIYKNISTEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSSV 4732
>SYTL5_RAT (Q812E4) Synaptotagmin-like protein 5| Length = 753 Score = 31.6 bits (70), Expect = 1.9 Identities = 25/90 (27%), Positives = 38/90 (42%), Gaps = 10/90 (11%) Frame = +2 Query: 233 GSDPEWNETFVFTVSE---NARELVIKLLDSDGGTEDDSVGEATIPLDGVYTEGSIPPTV 403 G++PE+NET +T+S R L + + D + +GE I D E Sbjct: 491 GTNPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIAFDSWNFENPCDEWF 550 Query: 404 YNVVKDE-------EYRGEIKIGLTFTPEE 472 K E +Y+GE+ I L + P E Sbjct: 551 VLQPKVELAPDISLQYKGELTIVLRYIPPE 580
>RP3A_BOVIN (Q06846) Rabphilin-3A (Exophilin-1)| Length = 704 Score = 31.6 bits (70), Expect = 1.9 Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 8/94 (8%) Frame = +2 Query: 107 TLEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKS----TVASGKGSDPEWNETFVF-- 268 +L ++ AKGL+ D DPY L KS T +P WNET V+ Sbjct: 418 SLHCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHG 477 Query: 269 -TVSENARE-LVIKLLDSDGGTEDDSVGEATIPL 364 T + R+ L I + D D ++ +GE L Sbjct: 478 ITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSL 511
>DYSF_MOUSE (Q9ESD7) Dysferlin (Dystrophy-associated fer-1-like protein)| (Fer-1-like protein 1) Length = 2083 Score = 31.6 bits (70), Expect = 1.9 Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 5/72 (6%) Frame = +2 Query: 182 VLRCTSQEQKSTVASGKGSDPEWNETFVFTVSENAREL-----VIKLLDSDGGTEDDSVG 346 V++ T+ Q KG+ P +NET F V ++ EL I ++DS D +G Sbjct: 243 VVKVTAAGQTKRTRIQKGNSPLFNETLFFNVFDSPLELFDEPIFITVVDSRSLRTDALLG 302 Query: 347 EATIPLDGVYTE 382 E + + VY E Sbjct: 303 EFRMDVGTVYRE 314 Score = 31.6 bits (70), Expect = 1.9 Identities = 26/95 (27%), Positives = 42/95 (44%), Gaps = 4/95 (4%) Frame = +2 Query: 119 LLVGAKGLENTDYLCNMDPYAVLRCTSQEQKSTVASGKGSDPEWNETFVFTVS----ENA 286 LL A L N DP A L ++++ V +P WNE F + + + + Sbjct: 5 LLARASNLPNVKKDRRSDPVASLIFRGVKKRTKVIKNS-VNPVWNEGFEWDLKGIPLDQS 63 Query: 287 RELVIKLLDSDGGTEDDSVGEATIPLDGVYTEGSI 391 EL++ + D + + +GEA IPL V S+ Sbjct: 64 SELLVVVKDHETMGRNRFLGEAKIPLQEVLATPSL 98
>DNE21_AGRT5 (Q8UAY9) Error-prone DNA polymerase 1 (EC 2.7.7.7)| Length = 1091 Score = 30.8 bits (68), Expect = 3.2 Identities = 15/34 (44%), Positives = 19/34 (55%) Frame = +1 Query: 130 SQGPREHRLPLQHGPVRGSEMHLAGAEEHRRLRK 231 S G R + PL HG RG E H ++HR +RK Sbjct: 1037 SVGERNNAFPLPHG--RGDEFHHGMPDDHRAIRK 1068
>KRH2_DROME (Q9V447) Protein Kr-h2| Length = 276 Score = 30.8 bits (68), Expect = 3.2 Identities = 35/107 (32%), Positives = 46/107 (42%), Gaps = 1/107 (0%) Frame = -2 Query: 568 LSRTIAQQNIRFFSR*LVPPTIVFLGLILIPSLLRSERQTDFDFSTVLFVLDNI-VNSWW 392 L+R A+ + + L+ I L+LIP LL S S L +LD I NSWW Sbjct: 109 LARLFAEDSCHYMMYSLIFFNIRPSLLVLIPVLLYSVLHAS---SYSLKLLDLIGQNSWW 165 Query: 391 DASFSIHSIQWDRCFTNAVIFRATITVEELDDELACVLRDGEHKGFV 251 A F I ++ F A I +AT E A VL H G + Sbjct: 166 GARFIISIVE----FQAANILKATAFCEIFIMPYAIVLAFMNHAGLM 208
>P3C2B_HUMAN (O00750) Phosphatidylinositol-4-phosphate 3-kinase C2| domain-containing beta polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-beta) (PtdIns-3-kinase C2 beta) (PI3K-C2beta) (C2-PI3K) Length = 1634 Score = 30.8 bits (68), Expect = 3.2 Identities = 26/106 (24%), Positives = 45/106 (42%), Gaps = 8/106 (7%) Frame = +2 Query: 71 GEIRPGEKMAQGTLEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKS----TVASGKGS 238 GE++ L ++++ +GL+ + DPY + QK+ T + K Sbjct: 1506 GEVKLSISYKNNKLFIMVMHIRGLQLLQDGNDPDPYVKIYLLPDPQKTTKRKTKVARKTC 1565 Query: 239 DPEWNETFVFTVSENA----RELVIKLLDSDGGTEDDSVGEATIPL 364 +P +NE V+ REL + +L G E+ +GE I L Sbjct: 1566 NPTYNEMLVYDGIPKGDLQQRELQLSVLSEQGFWENVLLGEVNIRL 1611
>GATE_HALSA (Q9HQ32) Glutamyl-tRNA(Gln) amidotransferase subunit E (EC 6.3.5.-)| (Glu-ADT subunit E) Length = 622 Score = 30.8 bits (68), Expect = 3.2 Identities = 26/100 (26%), Positives = 39/100 (39%), Gaps = 10/100 (10%) Frame = +2 Query: 128 GAKGLENTDYLCNMDPYAVLRCTSQEQKSTVASGK-------GSDPEWNETFVFTVSENA 286 GA G+ +TD L Y V + V +G+ DPE + V+E A Sbjct: 339 GAGGIFHTDEL---PAYGVTAAEVAALRDAVGAGEDDAVAIVADDPETAAQSIQAVAERA 395 Query: 287 RELVIKLLDSDGGTEDDSVGEATIPLDG---VYTEGSIPP 397 + + + G DD + PL G +Y E +PP Sbjct: 396 ETAMAGVPEETRGANDDGTSKYLRPLPGAARMYPETDVPP 435
>RIMS2_MOUSE (Q9EQZ7) Regulating synaptic membrane exocytosis protein 2| (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2) Length = 1530 Score = 30.4 bits (67), Expect = 4.2 Identities = 26/96 (27%), Positives = 46/96 (47%), Gaps = 10/96 (10%) Frame = +2 Query: 110 LEVLLVGAKGLENTDYLCNMDPYAVLRC----TSQEQKSTVASGKGSDPEWNETFVFTVS 277 L V ++GAK L + + +PY + + + ++ T K +P+WN+TF+++ Sbjct: 831 LIVTILGAKDLPSREDGRPRNPYVKIYFLPDRSDKNKRRTKTVKKTLEPKWNQTFIYSPV 890 Query: 278 E----NARELVIKLLDSDGGTEDDS--VGEATIPLD 367 R L I L D E++S +GE I L+ Sbjct: 891 HRREFRERMLEITLWDQARVREEESEFLGEILIELE 926
>RP3A_RAT (P47709) Rabphilin-3A (Exophilin-1)| Length = 684 Score = 30.4 bits (67), Expect = 4.2 Identities = 27/93 (29%), Positives = 39/93 (41%), Gaps = 8/93 (8%) Frame = +2 Query: 110 LEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKS----TVASGKGSDPEWNETFVF--- 268 L+ ++ AKGL+ D DPY L KS T +P WNET + Sbjct: 399 LQCTIIRAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPVWNETLQYHGI 458 Query: 269 TVSENARE-LVIKLLDSDGGTEDDSVGEATIPL 364 T + R+ L I + D D ++ +GE L Sbjct: 459 TEEDMQRKTLRISVCDEDKFGHNEFIGETRFSL 491
>RIMS2_HUMAN (Q9UQ26) Regulating synaptic membrane exocytosis protein 2| (Rab3-interacting molecule 2) (RIM 2) Length = 1411 Score = 30.4 bits (67), Expect = 4.2 Identities = 26/96 (27%), Positives = 46/96 (47%), Gaps = 10/96 (10%) Frame = +2 Query: 110 LEVLLVGAKGLENTDYLCNMDPYAVLRC----TSQEQKSTVASGKGSDPEWNETFVFTVS 277 L V ++GAK L + + +PY + + + ++ T K +P+WN+TF+++ Sbjct: 822 LIVTILGAKDLPSREDGRPRNPYVKIYFLPDRSDKNKRRTKTVKKTLEPKWNQTFIYSPV 881 Query: 278 E----NARELVIKLLDSDGGTEDDS--VGEATIPLD 367 R L I L D E++S +GE I L+ Sbjct: 882 HRREFRERMLEITLWDQARVREEESEFLGEILIELE 917
>RP3A_MOUSE (P47708) Rabphilin-3A (Exophilin-1)| Length = 681 Score = 30.4 bits (67), Expect = 4.2 Identities = 27/93 (29%), Positives = 39/93 (41%), Gaps = 8/93 (8%) Frame = +2 Query: 110 LEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKS----TVASGKGSDPEWNETFVF--- 268 L+ ++ AKGL+ D DPY L KS T +P WNET + Sbjct: 396 LQCTIIRAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPVWNETLQYHGI 455 Query: 269 TVSENARE-LVIKLLDSDGGTEDDSVGEATIPL 364 T + R+ L I + D D ++ +GE L Sbjct: 456 TEEDMQRKTLRISVCDEDKFGHNEFIGETRFSL 488
>RIMS2_RAT (Q9JIS1) Regulating synaptic membrane exocytosis protein 2| (Rab3-interacting molecule 2) (RIM 2) Length = 1555 Score = 30.4 bits (67), Expect = 4.2 Identities = 26/96 (27%), Positives = 46/96 (47%), Gaps = 10/96 (10%) Frame = +2 Query: 110 LEVLLVGAKGLENTDYLCNMDPYAVLRC----TSQEQKSTVASGKGSDPEWNETFVFTVS 277 L V ++GAK L + + +PY + + + ++ T K +P+WN+TF+++ Sbjct: 760 LIVTILGAKDLPSREDGRPRNPYVKIYFLPDRSDKNKRRTKTVKKTLEPKWNQTFIYSPV 819 Query: 278 E----NARELVIKLLDSDGGTEDDS--VGEATIPLD 367 R L I L D E++S +GE I L+ Sbjct: 820 HRREFRERMLEITLWDQARVREEESEFLGEILIELE 855
>MMSA_ANOGA (Q7QC84) Probable methylmalonate-semialdehyde dehydrogenase| [acylating], mitochondrial precursor (EC 1.2.1.27) (MMSDH) (Malonate-semialdehyde dehydrogenase [acylating]) (EC 1.2.1.18) Length = 521 Score = 30.0 bits (66), Expect = 5.5 Identities = 26/109 (23%), Positives = 44/109 (40%), Gaps = 17/109 (15%) Frame = +2 Query: 182 VLRCTSQEQKSTVASGKGSDPEWNETFVFT-----------VSENARELVIKLLDSDGGT 328 V +CT E ++ V S K + W ++ + + + N EL + G T Sbjct: 58 VPKCTQDEMQTAVESSKKAYKTWRQSSILSRQQVMLKLQHIIRNNMSELAKNITKEQGKT 117 Query: 329 EDDSVGEATIPLDGV-----YTEGSIPPTVYNVVKD-EEYRGEIKIGLT 457 D+ G+ L V T + TV N+ KD + Y + +G+T Sbjct: 118 LIDAEGDVLRGLQVVEHCCSITSLQMGETVPNIAKDMDTYSYHLPLGVT 166
>CU025_HUMAN (Q9Y426) Protein C21orf25 precursor| Length = 696 Score = 30.0 bits (66), Expect = 5.5 Identities = 21/93 (22%), Positives = 45/93 (48%), Gaps = 1/93 (1%) Frame = +2 Query: 92 KMAQGTLEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQK-STVASGKGSDPEWNETFVF 268 K+ + VLL+ G +++ V++ Q+ S+ + D W E F F Sbjct: 264 KLLVRNIHVLLLSEPGASG-----HINAVCVVQLNDPVQRFSSTLTKNTPDLMWEEEFTF 318 Query: 269 TVSENARELVIKLLDSDGGTEDDSVGEATIPLD 367 ++ ++EL +++ ++ G + + + AT+PLD Sbjct: 319 ELNAKSKELHLQISEA-GRSSEGLLATATVPLD 350
>HERC2_DROME (Q9VR91) HECT domain and RCC1-like domain-containing protein 2| Length = 4912 Score = 30.0 bits (66), Expect = 5.5 Identities = 24/97 (24%), Positives = 39/97 (40%), Gaps = 26/97 (26%) Frame = +2 Query: 29 LLNVVPHLRSWVGEGEIRPGEKMAQGTL--------------------------EVLLVG 130 LL V+ L +GEGE+R G+ M + +LL G Sbjct: 1244 LLRVLDRLNRALGEGELRDGDDMGWPGIICRGGPKGGPPPADPETHYVRRADMENLLLDG 1303 Query: 131 AKGLENTDYLCNMDPYAVLRCTSQEQKSTVASGKGSD 241 ++ + Y+C++ Y C S+ +S + SG G D Sbjct: 1304 SRCIILAGYVCDLSGY---NCESETLRSVLDSGLGKD 1337
>OTOF_MOUSE (Q9ESF1) Otoferlin (Fer-1-like protein 2)| Length = 1997 Score = 30.0 bits (66), Expect = 5.5 Identities = 24/83 (28%), Positives = 39/83 (46%), Gaps = 2/83 (2%) Frame = +2 Query: 143 ENTDYLCNMDPYAVLRCTSQEQKSTVASGKGSDPEWNETFVFT--VSENARELVIKLLDS 316 EN D + DPY + Q+ K++V +P WNE VFT + + +++ DS Sbjct: 446 ENKDLV---DPYVQVFFAGQKGKTSVQKSS-YEPLWNEQVVFTDLFPPLCKRMKVQIRDS 501 Query: 317 DGGTEDDSVGEATIPLDGVYTEG 385 D D ++G I L + +G Sbjct: 502 D-KVNDVAIGTHFIDLRKISNDG 523
>OTOF_HUMAN (Q9HC10) Otoferlin (Fer-1-like protein 2)| Length = 1997 Score = 30.0 bits (66), Expect = 5.5 Identities = 24/83 (28%), Positives = 39/83 (46%), Gaps = 2/83 (2%) Frame = +2 Query: 143 ENTDYLCNMDPYAVLRCTSQEQKSTVASGKGSDPEWNETFVFT--VSENARELVIKLLDS 316 EN D + DPY + Q+ K++V +P WNE VFT + + +++ DS Sbjct: 447 ENKDLV---DPYVQVFFAGQKGKTSVQKSS-YEPLWNEQVVFTDLFPPLCKRMKVQIRDS 502 Query: 317 DGGTEDDSVGEATIPLDGVYTEG 385 D D ++G I L + +G Sbjct: 503 D-KVNDVAIGTHFIDLRKISNDG 524
>Y1913_ENTFA (Q833N1) UPF0161 protein EF1913| Length = 100 Score = 30.0 bits (66), Expect = 5.5 Identities = 14/50 (28%), Positives = 24/50 (48%) Frame = +2 Query: 362 LDGVYTEGSIPPTVYNVVKDEEYRGEIKIGLTFTPEEARDEDQPEENYGG 511 +D ++T GS+ T V + +K G+ + P + R P+E Y G Sbjct: 35 IDAIHTHGSVKGTTMGVARILRCHPFVKGGIDYVPLKFRLTKNPDETYHG 84
>P3C2A_PONPY (Q5RAY1) Phosphatidylinositol-4-phosphate 3-kinase C2| domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) Length = 1685 Score = 29.6 bits (65), Expect = 7.2 Identities = 26/106 (24%), Positives = 47/106 (44%), Gaps = 8/106 (7%) Frame = +2 Query: 71 GEIRPGEKMAQGTLEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKS----TVASGKGS 238 G ++ GTL ++++ K L D + +PY K+ T S K Sbjct: 1560 GAVKLSISYRNGTLFIMVMHTKDLVTEDG-ADPNPYVKTYLLPDNHKTSKRKTKISRKTR 1618 Query: 239 DPEWNETFVFT----VSENARELVIKLLDSDGGTEDDSVGEATIPL 364 +P +NE V++ + REL + +L ++ E+ +G T+PL Sbjct: 1619 NPTFNEMLVYSGYSKETLRQRELQLSVLSAESLRENFFLGGVTLPL 1664
>PKP4_MOUSE (Q68FH0) Plakophilin-4 (Armadillo-related protein)| Length = 1190 Score = 29.3 bits (64), Expect = 9.4 Identities = 27/59 (45%), Positives = 35/59 (59%), Gaps = 4/59 (6%) Frame = -3 Query: 189 LRTAYGSMLQR*SVF-SRPLAPTS-STSSVPCA-IFSPGLISP-SPTQLRR*GTTLSRQ 25 LRT+ GS SV SRPL P++ S+S++P SP P SPT +RR G+ SRQ Sbjct: 236 LRTSLGSGFGSPSVTDSRPLNPSAYSSSTLPAQRAASPYSQRPASPTAVRRVGSVTSRQ 294
>UNC13_CAEEL (P27715) Phorbol ester/diacylglycerol-binding protein unc-13| (Uncoordinated protein 13) Length = 2155 Score = 29.3 bits (64), Expect = 9.4 Identities = 21/74 (28%), Positives = 34/74 (45%) Frame = +2 Query: 98 AQGTLEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKSTVASGKGSDPEWNETFVFTVS 277 A+ TL VL A+GL D DPY + + ++ T + +P WNE F F Sbjct: 1157 AKITLTVLC--AQGLIAKDKTGKSDPYVTAQ-VGKTKRRTRTIHQELNPVWNEKFHFECH 1213 Query: 278 ENARELVIKLLDSD 319 + + +++ D D Sbjct: 1214 NSTDRIKVRVWDED 1227
>PCLO_RAT (Q9JKS6) Protein piccolo (Aczonin) (Multidomain presynaptic| cytomatrix protein) Length = 5085 Score = 29.3 bits (64), Expect = 9.4 Identities = 29/116 (25%), Positives = 50/116 (43%), Gaps = 18/116 (15%) Frame = +2 Query: 71 GEIRPGEKMAQGTLEVLLVGAKGLENTDYLCNMDPYA-------------VLRCTSQEQK 211 GEI+ G L + ++ A+ L D DP+ V +++ ++ Sbjct: 4641 GEIQLQINYDLGNLIIHILQARNLVPRDNNGYSDPFVKVYLLPGRGQVMVVQNASAEYKR 4700 Query: 212 STVASGKGSDPEWNETFVFTVSENARELVIKLL-----DSDGGTEDDSVGEATIPL 364 T K +PEWN+T ++ S + +L+ K L D D + +D +GE I L Sbjct: 4701 RTKYVQKSLNPEWNQTVIYK-SISMEQLMKKTLEVTVWDYDRFSSNDFLGEVLIDL 4755
>P3C2A_HUMAN (O00443) Phosphatidylinositol-4-phosphate 3-kinase C2| domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) Length = 1686 Score = 29.3 bits (64), Expect = 9.4 Identities = 26/106 (24%), Positives = 47/106 (44%), Gaps = 8/106 (7%) Frame = +2 Query: 71 GEIRPGEKMAQGTLEVLLVGAKGLENTDYLCNMDPYAVLRCTSQEQKS----TVASGKGS 238 G ++ GTL ++++ K L D + +PY K+ T S K Sbjct: 1561 GAVKLSISYRNGTLFIMVMHIKDLVTEDG-ADPNPYVKTYLLPDNHKTSKRKTKISRKTR 1619 Query: 239 DPEWNETFVFT----VSENARELVIKLLDSDGGTEDDSVGEATIPL 364 +P +NE V++ + REL + +L ++ E+ +G T+PL Sbjct: 1620 NPTFNEMLVYSGYSKETLRQRELQLSVLSAESLRENFFLGGVTLPL 1665
>OTX2_MOUSE (P80206) Homeobox protein OTX2| Length = 289 Score = 29.3 bits (64), Expect = 9.4 Identities = 15/41 (36%), Positives = 22/41 (53%) Frame = -3 Query: 129 PTSSTSSVPCAIFSPGLISPSPTQLRR*GTTLSRQHDWTAT 7 PT ++SS P +I+SP ISP L + + R + T T Sbjct: 140 PTIASSSAPVSIWSPASISPLSDPLSTSSSCMQRSYPMTYT 180
>OTX2_HUMAN (P32243) Homeobox protein OTX2| Length = 289 Score = 29.3 bits (64), Expect = 9.4 Identities = 15/41 (36%), Positives = 22/41 (53%) Frame = -3 Query: 129 PTSSTSSVPCAIFSPGLISPSPTQLRR*GTTLSRQHDWTAT 7 PT ++SS P +I+SP ISP L + + R + T T Sbjct: 140 PTIASSSAPVSIWSPASISPLSDPLSTSSSCMQRSYPMTYT 180 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 80,453,218 Number of Sequences: 219361 Number of extensions: 1535140 Number of successful extensions: 5326 Number of sequences better than 10.0: 129 Number of HSP's better than 10.0 without gapping: 5113 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5307 length of database: 80,573,946 effective HSP length: 107 effective length of database: 57,102,319 effective search space used: 5424720305 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
