ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bags32m17 |
|---|---|
| Clone Library Name | barley_pub |
>PDPK1_MOUSE (Q9Z2A0) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (mPDK1) Length = 559 Score = 183 bits (464), Expect = 3e-46 Identities = 94/191 (49%), Positives = 122/191 (63%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++L+FTFQD LY L + GEL I + G E RFY AEIV LEYLH Sbjct: 143 PFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGK 202 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+IHRD+KPEN+LL D HI+I DFG+ K + P S RA +FVGTA YV PE Sbjct: 203 GIIHRDLKPENILLNEDMHIQITDFGTAKV-------LSPESKQARANSFVGTAQYVSPE 255 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 +L A +DLWALGC ++Q+++G PF+ +E+LIFQ+II + FPE F +ARDL Sbjct: 256 LLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYHFPEKFFPKARDL 315 Query: 542 IDKLLDVDPTK 574 ++KLL +D TK Sbjct: 316 VEKLLVLDATK 326
>PDPK1_RAT (O55173) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (Protein kinase B kinase) (PkB kinase) Length = 559 Score = 182 bits (463), Expect = 5e-46 Identities = 94/191 (49%), Positives = 123/191 (64%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++L+FTFQD LY L + GEL I + G E RFY AEIV LEYLH Sbjct: 143 PFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGK 202 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+IHRD+KPEN+LL D HI+I DFG+ K + P+S RA +FVGTA YV PE Sbjct: 203 GIIHRDLKPENILLNEDMHIQITDFGTAKV-------LSPDSKQARANSFVGTAQYVSPE 255 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 +L A +DLWALGC ++Q+++G PF+ +E+LIFQ+II + FPE F +ARDL Sbjct: 256 LLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDL 315 Query: 542 IDKLLDVDPTK 574 ++KLL +D TK Sbjct: 316 VEKLLVLDATK 326
>PDPK1_HUMAN (O15530) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (hPDK1) Length = 556 Score = 182 bits (462), Expect = 6e-46 Identities = 94/191 (49%), Positives = 122/191 (63%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++L+FTFQD LY L + GEL I + G E RFY AEIV LEYLH Sbjct: 140 PFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGK 199 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+IHRD+KPEN+LL D HI+I DFG+ K + P S RA +FVGTA YV PE Sbjct: 200 GIIHRDLKPENILLNEDMHIQITDFGTAK-------VLSPESKQARANSFVGTAQYVSPE 252 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 +L A +DLWALGC ++Q+++G PF+ +E+LIFQ+II + FPE F +ARDL Sbjct: 253 LLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDL 312 Query: 542 IDKLLDVDPTK 574 ++KLL +D TK Sbjct: 313 VEKLLVLDATK 323
>KSG1_SCHPO (Q12701) Serine/threonine-protein kinase ksg1 (EC 2.7.11.1)| Length = 592 Score = 165 bits (418), Expect = 7e-41 Identities = 92/197 (46%), Positives = 119/197 (60%), Gaps = 8/197 (4%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 PG I+LF+TFQD+++LY L GEL D I + GR +E A++YAA IVD ++Y+H Sbjct: 158 PGFIKLFYTFQDAHNLYFVLSLARNGELLDYINKLGRFNEICAQYYAALIVDSIDYMHGR 217 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVK--------PTVDTPIKVLPNSTNERACTFVG 337 G+IHRD+KPEN+LL + KI DFGS K DT P + + +FVG Sbjct: 218 GVIHRDLKPENILLDDNMRTKITDFGSAKILNSSHGSHEEDTHHADKPQAHSR---SFVG 274 Query: 338 TAAYVPPEVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEF 517 TA YV PEVL+ A +D+WA GC LFQML+G PF +E+L FQ I+ P Sbjct: 275 TARYVSPEVLSDKIAGTASDIWAFGCILFQMLAGKPPFVAGNEYLTFQSILHLSYEIPPD 334 Query: 518 FSDEARDLIDKLLDVDP 568 SD A DLI KLL +DP Sbjct: 335 ISDVASDLIKKLLVLDP 351
>KOK0_YEAST (Q12236) Probable serine/threonine-protein kinase YOL100W (EC| 2.7.11.1) Length = 1081 Score = 162 bits (409), Expect = 8e-40 Identities = 84/188 (44%), Positives = 117/188 (62%), Gaps = 3/188 (1%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P V+RLF TFQD SLY LE G+ + + G L E AR+YAA+I+D ++YLHS Sbjct: 238 PSVVRLFSTFQDESSLYFLLEYAPNGDFLSLMKKYGSLDETCARYYAAQIIDAIDYLHSN 297 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVK---PTVDTPIKVLPNSTNERACTFVGTAAYV 352 G+IHRD+KPEN+LL + IK+ DFG+ K PT + + + R+ +FVGTA YV Sbjct: 298 GIIHRDIKPENILLDGEMKIKLTDFGTAKLLNPT-NNSVSKPEYDLSTRSKSFVGTAEYV 356 Query: 353 PPEVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEA 532 PE+LN + + D+WA GC LFQM++G PFK +E+L FQ+++ F F Sbjct: 357 SPELLNDSFTDYRCDIWAFGCILFQMIAGKPPFKATNEYLTFQKVMKVQYAFTPGFPLII 416 Query: 533 RDLIDKLL 556 RDL+ K+L Sbjct: 417 RDLVKKIL 424
>PKH1_YEAST (Q03407) Serine/threonine-protein kinase PKH1 (EC 2.7.11.1)| (3-phosphoinositide-dependent protein kinase 1) Length = 766 Score = 159 bits (401), Expect = 7e-39 Identities = 81/192 (42%), Positives = 116/192 (60%), Gaps = 4/192 (2%) Frame = +2 Query: 5 GVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSVG 184 G+ +LFFTFQD SLY LE G+ I + G L+E AR+YA++I+D ++ LH++G Sbjct: 185 GIFKLFFTFQDEASLYFLLEYAPHGDFLGLIKKYGSLNETCARYYASQIIDAVDSLHNIG 244 Query: 185 LIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPN----STNERACTFVGTAAYV 352 +IHRD+KPEN+LL + +K+ DFG+ K + P ++ +FVGTA YV Sbjct: 245 IIHRDIKPENILLDKNMKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFVGTAEYV 304 Query: 353 PPEVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEA 532 PE+LN D+WA GC L+QML+G PFK A+E+L FQ+++ F F Sbjct: 305 SPELLNDNYTDSRCDIWAFGCILYQMLAGKPPFKAANEYLTFQKVMKIQYAFTAGFPQIV 364 Query: 533 RDLIDKLLDVDP 568 +DL+ KLL DP Sbjct: 365 KDLVKKLLVRDP 376
>PRKX_HUMAN (P51817) Serine/threonine-protein kinase PRKX (EC 2.7.11.1)| (Protein kinase PKX1) Length = 358 Score = 156 bits (394), Expect = 5e-38 Identities = 85/191 (44%), Positives = 112/191 (58%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +IRLF+T+ D LYM +E GGELF + +GR S FY+AEI+ +EYLHS Sbjct: 107 PFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGLFYSAEIICAIEYLHSK 166 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +++RD+KPEN+LL DGHIK+ DFG K VD R T GT Y+ PE Sbjct: 167 EIVYRDLKPENILLDRDGHIKLTDFGFAKKLVD------------RTWTLCGTPEYLAPE 214 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 V+ S D WALG +F+MLSG PF D + + I+Q+I+A + FP +DL Sbjct: 215 VIQSKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKIDFPRHLDFHVKDL 274 Query: 542 IDKLLDVDPTK 574 I KLL VD T+ Sbjct: 275 IKKLLVVDRTR 285
>KAPC_CAEEL (P21137) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) (PKA C) Length = 404 Score = 151 bits (382), Expect = 1e-36 Identities = 80/191 (41%), Positives = 114/191 (59%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ + F+F+D+ +LYM LE GGE+F + R GR SE +RFYAA+IV EYLHS+ Sbjct: 139 PFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSL 198 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 LI+RD+KPENLL+ S G++KI DFG K R T GT Y+ PE Sbjct: 199 DLIYRDLKPENLLIDSTGYLKITDFGFAK------------RVKGRTWTLCGTPEYLAPE 246 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ S D WALG +++M +G PF I+++I++ ++FP FS+E +DL Sbjct: 247 IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDL 306 Query: 542 IDKLLDVDPTK 574 + LL VD TK Sbjct: 307 LKNLLQVDLTK 317
>KAPA_YEAST (P06244) cAMP-dependent protein kinase type 1 (EC 2.7.11.11) (PKA| 1) (CDC25-suppressing protein kinase) (PK-25) Length = 397 Score = 151 bits (381), Expect = 1e-36 Identities = 74/188 (39%), Positives = 115/188 (61%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +IR++ TFQD+ ++M ++ EGGELF + + R A+FYAAE+ LEYLHS Sbjct: 145 PFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSK 204 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +I+RD+KPEN+LL +GHIKI DFG K D T GT Y+ PE Sbjct: 205 DIIYRDLKPENILLDKNGHIKITDFGFAKYVPDV------------TYTLCGTPDYIAPE 252 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 V+++ P D W+ G +++ML+G +PF D++ +++I+ +LRFP FF+++ +DL Sbjct: 253 VVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFPPFFNEDVKDL 312 Query: 542 IDKLLDVD 565 + +L+ D Sbjct: 313 LSRLITRD 320
>KAPCB_PIG (P05383) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 150 bits (379), Expect = 2e-36 Identities = 80/191 (41%), Positives = 113/191 (59%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++RL F+F+D+ +LYM +E GGE+F + R GR SE ARFYAA+IV EYLHS+ Sbjct: 101 PFLVRLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSL 160 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 LI+RD+KPENLL+ G+I++ DFG K R T GT Y+ PE Sbjct: 161 DLIYRDLKPENLLIDHQGYIQVTDFGFAK------------RVKGRTWTLCGTPEYLAPE 208 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ S D WALG +++M +G PF I+++I++ +RFP FS + +DL Sbjct: 209 IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDL 268 Query: 542 IDKLLDVDPTK 574 + LL VD TK Sbjct: 269 LRNLLQVDLTK 279
>KAPCA_CANFA (Q8MJ44) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 349 Score = 149 bits (377), Expect = 4e-36 Identities = 79/191 (41%), Positives = 113/191 (59%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +++L F+F+D+ +LYM +E GGE+F + R GR SE ARFYAA+IV EYLHS+ Sbjct: 100 PFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSL 159 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 LI+RD+KPENLL+ G+I++ DFG K R T GT Y+ PE Sbjct: 160 DLIYRDLKPENLLIDQQGYIQVTDFGFAK------------RVKGRTWTLCGTPEYLAPE 207 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ S D WALG +++M +G PF I+++I++ +RFP FS + +DL Sbjct: 208 IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDL 267 Query: 542 IDKLLDVDPTK 574 + LL VD TK Sbjct: 268 LRNLLQVDLTK 278
>KAPCA_SHEEP (Q9MZD9) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 149 bits (377), Expect = 4e-36 Identities = 79/191 (41%), Positives = 113/191 (59%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +++L F+F+D+ +LYM +E GGE+F + R GR SE ARFYAA+IV EYLHS+ Sbjct: 101 PFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSL 160 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 LI+RD+KPENLL+ G+I++ DFG K R T GT Y+ PE Sbjct: 161 DLIYRDLKPENLLIDQQGYIQVTDFGFAK------------RVKGRTWTLCGTPEYLAPE 208 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ S D WALG +++M +G PF I+++I++ +RFP FS + +DL Sbjct: 209 IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDL 268 Query: 542 IDKLLDVDPTK 574 + LL VD TK Sbjct: 269 LRNLLQVDLTK 279
>KAPCA_RAT (P27791) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 149 bits (377), Expect = 4e-36 Identities = 79/191 (41%), Positives = 113/191 (59%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +++L F+F+D+ +LYM +E GGE+F + R GR SE ARFYAA+IV EYLHS+ Sbjct: 101 PFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSL 160 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 LI+RD+KPENLL+ G+I++ DFG K R T GT Y+ PE Sbjct: 161 DLIYRDLKPENLLIDQQGYIQVTDFGFAK------------RVKGRTWTLCGTPEYLAPE 208 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ S D WALG +++M +G PF I+++I++ +RFP FS + +DL Sbjct: 209 IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDL 268 Query: 542 IDKLLDVDPTK 574 + LL VD TK Sbjct: 269 LRNLLQVDLTK 279
>KAPCA_MOUSE (P05132) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 149 bits (377), Expect = 4e-36 Identities = 79/191 (41%), Positives = 113/191 (59%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +++L F+F+D+ +LYM +E GGE+F + R GR SE ARFYAA+IV EYLHS+ Sbjct: 101 PFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSL 160 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 LI+RD+KPENLL+ G+I++ DFG K R T GT Y+ PE Sbjct: 161 DLIYRDLKPENLLIDQQGYIQVTDFGFAK------------RVKGRTWTLCGTPEYLAPE 208 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ S D WALG +++M +G PF I+++I++ +RFP FS + +DL Sbjct: 209 IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDL 268 Query: 542 IDKLLDVDPTK 574 + LL VD TK Sbjct: 269 LRNLLQVDLTK 279
>KAPCA_HUMAN (P17612) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 149 bits (377), Expect = 4e-36 Identities = 79/191 (41%), Positives = 113/191 (59%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +++L F+F+D+ +LYM +E GGE+F + R GR SE ARFYAA+IV EYLHS+ Sbjct: 101 PFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSL 160 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 LI+RD+KPENLL+ G+I++ DFG K R T GT Y+ PE Sbjct: 161 DLIYRDLKPENLLIDQQGYIQVTDFGFAK------------RVKGRTWTLCGTPEYLAPE 208 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ S D WALG +++M +G PF I+++I++ +RFP FS + +DL Sbjct: 209 IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDL 268 Query: 542 IDKLLDVDPTK 574 + LL VD TK Sbjct: 269 LRNLLQVDLTK 279
>KAPCA_CRIGR (P25321) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 149 bits (377), Expect = 4e-36 Identities = 79/191 (41%), Positives = 113/191 (59%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +++L F+F+D+ +LYM +E GGE+F + R GR SE ARFYAA+IV EYLHS+ Sbjct: 101 PFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSL 160 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 LI+RD+KPENLL+ G+I++ DFG K R T GT Y+ PE Sbjct: 161 DLIYRDLKPENLLIDQQGYIQVTDFGFAK------------RVKGRTWTLCGTPEYLAPE 208 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ S D WALG +++M +G PF I+++I++ +RFP FS + +DL Sbjct: 209 IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDL 268 Query: 542 IDKLLDVDPTK 574 + LL VD TK Sbjct: 269 LRNLLQVDLTK 279
>KAPCA_BOVIN (P00517) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 149 bits (377), Expect = 4e-36 Identities = 79/191 (41%), Positives = 113/191 (59%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +++L F+F+D+ +LYM +E GGE+F + R GR SE ARFYAA+IV EYLHS+ Sbjct: 101 PFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSL 160 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 LI+RD+KPENLL+ G+I++ DFG K R T GT Y+ PE Sbjct: 161 DLIYRDLKPENLLIDQQGYIQVTDFGFAK------------RVKGRTWTLCGTPEYLAPE 208 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ S D WALG +++M +G PF I+++I++ +RFP FS + +DL Sbjct: 209 IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDL 268 Query: 542 IDKLLDVDPTK 574 + LL VD TK Sbjct: 269 LRNLLQVDLTK 279
>KAPCB_RAT (P68182) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 149 bits (376), Expect = 6e-36 Identities = 79/191 (41%), Positives = 113/191 (59%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++RL ++F+D+ +LYM +E GGE+F + R GR SE ARFYAA+IV EYLHS+ Sbjct: 101 PFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSL 160 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 LI+RD+KPENLL+ G+I++ DFG K R T GT Y+ PE Sbjct: 161 DLIYRDLKPENLLIDHQGYIQVTDFGFAK------------RVKGRTWTLCGTPEYLAPE 208 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ S D WALG +++M +G PF I+++I++ +RFP FS + +DL Sbjct: 209 IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDL 268 Query: 542 IDKLLDVDPTK 574 + LL VD TK Sbjct: 269 LRNLLQVDLTK 279
>KAPCB_MOUSE (P68181) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 149 bits (376), Expect = 6e-36 Identities = 79/191 (41%), Positives = 113/191 (59%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++RL ++F+D+ +LYM +E GGE+F + R GR SE ARFYAA+IV EYLHS+ Sbjct: 101 PFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSL 160 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 LI+RD+KPENLL+ G+I++ DFG K R T GT Y+ PE Sbjct: 161 DLIYRDLKPENLLIDHQGYIQVTDFGFAK------------RVKGRTWTLCGTPEYLAPE 208 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ S D WALG +++M +G PF I+++I++ +RFP FS + +DL Sbjct: 209 IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDL 268 Query: 542 IDKLLDVDPTK 574 + LL VD TK Sbjct: 269 LRNLLQVDLTK 279
>KAPCB_CRIGR (P68180) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 149 bits (376), Expect = 6e-36 Identities = 79/191 (41%), Positives = 113/191 (59%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++RL ++F+D+ +LYM +E GGE+F + R GR SE ARFYAA+IV EYLHS+ Sbjct: 101 PFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSL 160 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 LI+RD+KPENLL+ G+I++ DFG K R T GT Y+ PE Sbjct: 161 DLIYRDLKPENLLIDHQGYIQVTDFGFAK------------RVKGRTWTLCGTPEYLAPE 208 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ S D WALG +++M +G PF I+++I++ +RFP FS + +DL Sbjct: 209 IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDL 268 Query: 542 IDKLLDVDPTK 574 + LL VD TK Sbjct: 269 LRNLLQVDLTK 279
>PKH3_ASHGO (Q753D9) Serine/threonine-protein kinase PKH3 (EC 2.7.11.1)| Length = 726 Score = 149 bits (376), Expect = 6e-36 Identities = 75/191 (39%), Positives = 119/191 (62%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 PG+I+L++TF D +LY ++ GGEL + R+ SE AR Y ++VD +EY+HS+ Sbjct: 71 PGIIKLYYTFHDQENLYFVMDLAPGGELLQLLRRQRVFSEAWARHYMCQLVDTVEYIHSM 130 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+IHRD+KPEN+LL +G + IADFG+ + + ++ A +FVGTA YV PE Sbjct: 131 GVIHRDLKPENVLLDKEGRLMIADFGAAYTVGQSD---AGSDGDKPATSFVGTAEYVSPE 187 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 +L + + +D+WALGC L+Q L G+ PF+ +E F++I+ D + + A L Sbjct: 188 LLLENKSYYSSDVWALGCMLYQFLQGTPPFRGQNEMETFEQIVNLDYTWRIPANPLAAGL 247 Query: 542 IDKLLDVDPTK 574 + K+L +DP++ Sbjct: 248 VSKILVLDPSQ 258
>KAPB2_BOVIN (P24256) cAMP-dependent protein kinase, beta-2-catalytic subunit| (EC 2.7.11.11) (PKA C-beta-2) Length = 397 Score = 149 bits (375), Expect = 7e-36 Identities = 79/191 (41%), Positives = 112/191 (58%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++RL + F+D+ +LYM +E GGE+F + R GR SE ARFYAA+IV EYLHS+ Sbjct: 148 PFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSL 207 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 LI+RD+KPENLL+ G+I++ DFG K R T GT Y+ PE Sbjct: 208 DLIYRDLKPENLLIDHQGYIQVTDFGFAK------------RVKGRTWTLCGTPEYLAPE 255 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ S D WALG +++M +G PF I+++I++ +RFP FS + +DL Sbjct: 256 IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDL 315 Query: 542 IDKLLDVDPTK 574 + LL VD TK Sbjct: 316 LRNLLQVDLTK 326
>KAPCB_HUMAN (P22694) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 149 bits (375), Expect = 7e-36 Identities = 79/191 (41%), Positives = 112/191 (58%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++RL + F+D+ +LYM +E GGE+F + R GR SE ARFYAA+IV EYLHS+ Sbjct: 101 PFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSL 160 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 LI+RD+KPENLL+ G+I++ DFG K R T GT Y+ PE Sbjct: 161 DLIYRDLKPENLLIDHQGYIQVTDFGFAK------------RVKGRTWTLCGTPEYLAPE 208 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ S D WALG +++M +G PF I+++I++ +RFP FS + +DL Sbjct: 209 IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDL 268 Query: 542 IDKLLDVDPTK 574 + LL VD TK Sbjct: 269 LRNLLQVDLTK 279
>KAPB1_BOVIN (P05131) cAMP-dependent protein kinase, beta-1-catalytic subunit| (EC 2.7.11.11) (PKA C-beta-1) Length = 350 Score = 149 bits (375), Expect = 7e-36 Identities = 79/191 (41%), Positives = 112/191 (58%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++RL + F+D+ +LYM +E GGE+F + R GR SE ARFYAA+IV EYLHS+ Sbjct: 101 PFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSL 160 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 LI+RD+KPENLL+ G+I++ DFG K R T GT Y+ PE Sbjct: 161 DLIYRDLKPENLLIDHQGYIQVTDFGFAK------------RVKGRTWTLCGTPEYLAPE 208 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ S D WALG +++M +G PF I+++I++ +RFP FS + +DL Sbjct: 209 IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDL 268 Query: 542 IDKLLDVDPTK 574 + LL VD TK Sbjct: 269 LRNLLQVDLTK 279
>KAPCA_PIG (P36887) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 148 bits (374), Expect = 9e-36 Identities = 78/191 (40%), Positives = 113/191 (59%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +++L ++F+D+ +LYM +E GGE+F + R GR SE ARFYAA+IV EYLHS+ Sbjct: 101 PFLVKLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSL 160 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 LI+RD+KPENLL+ G+I++ DFG K R T GT Y+ PE Sbjct: 161 DLIYRDLKPENLLIDQQGYIQVTDFGFAK------------RVKGRTWTLCGTPEYLAPE 208 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ S D WALG +++M +G PF I+++I++ +RFP FS + +DL Sbjct: 209 IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDL 268 Query: 542 IDKLLDVDPTK 574 + LL VD TK Sbjct: 269 LRNLLQVDLTK 279
>KAPC_YEAST (P05986) cAMP-dependent protein kinase type 3 (EC 2.7.11.11) (PKA| 3) Length = 398 Score = 148 bits (374), Expect = 9e-36 Identities = 75/188 (39%), Positives = 113/188 (60%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +IR++ TFQDS ++M ++ EGGELF + + R A+FYAAE+ LEYLHS Sbjct: 146 PFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSK 205 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +I+RD+KPEN+LL +GHIKI DFG K D T GT Y+ PE Sbjct: 206 DIIYRDLKPENILLDKNGHIKITDFGFAKYVPDV------------TYTLCGTPDYIAPE 253 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 V+++ P D W+ G +++ML+G +PF +++ ++ I+ +L+FP FF +A+DL Sbjct: 254 VVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFFHPDAQDL 313 Query: 542 IDKLLDVD 565 + KL+ D Sbjct: 314 LKKLITRD 321
>PRKX_MOUSE (Q922R0) Serine/threonine-protein kinase PRKX (EC 2.7.11.1)| (PKA-related protein kinase) Length = 355 Score = 147 bits (372), Expect = 2e-35 Identities = 83/191 (43%), Positives = 112/191 (58%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +I+L +T D+ LYM +E GGELF + +GR S + FYA EIV +EYLHS Sbjct: 104 PFLIKLLWTGHDNRFLYMLMEFVPGGELFTYLRNRGRFSSVASVFYATEIVCAIEYLHSK 163 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +++RD+KPEN+LL +GHIK+ DFG K VD R T GT Y+ PE Sbjct: 164 EIVYRDLKPENILLDREGHIKLTDFGFAKKLVD------------RTWTLCGTPEYLAPE 211 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 V+ S D WALG +F+MLSG PF D + + I+Q+I+A + FP ++DL Sbjct: 212 VIQSKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILACKIDFPRQLDFTSKDL 271 Query: 542 IDKLLDVDPTK 574 I KLL VD T+ Sbjct: 272 IKKLLVVDRTR 282
>KOIA_SCHPO (Q9Y7J6) Putative serine/threonine-protein kinase C1778.10c (EC| 2.7.11.1) Length = 550 Score = 146 bits (369), Expect = 4e-35 Identities = 77/190 (40%), Positives = 109/190 (57%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 PG+ RLF TFQD LY LE GEL I + L E+ RFYAAEI+ +EY+HS Sbjct: 113 PGISRLFHTFQDDLKLYYVLELAPNGELLQYIKKYRFLDENCVRFYAAEILSSIEYMHSC 172 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+IHRD+KPEN+L + H+KI DFG+ K + P V +FVGTA YV PE Sbjct: 173 GIIHRDLKPENILFDGNMHVKITDFGTAK--ILPPKYVNSPDYTTFPSSFVGTAEYVAPE 230 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 +L+ + +DLWA C ++QM+ GS PF ++ IF++I++ + P+ + L Sbjct: 231 LLSRQVVSKSSDLWAFACVVYQMIVGSPPFHGSNPNNIFKKIMSLEYELPKLLPPDIVPL 290 Query: 542 IDKLLDVDPT 571 L + P+ Sbjct: 291 FSHLFRIQPS 300
>KAPC_DICDI (P34099) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) Length = 648 Score = 145 bits (366), Expect = 8e-35 Identities = 77/191 (40%), Positives = 108/191 (56%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L+ FQD LY+ E GGE+F + + + S A+FYAAEIV LE+LH Sbjct: 394 PFIVNLYQAFQDEKKLYLLFEYVAGGEVFTHLRKSMKFSNSTAKFYAAEIVLALEFLHKQ 453 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +++RD+KPENLL+ + GHIKI DFG K D R T GT Y+ PE Sbjct: 454 NIVYRDLKPENLLIDNQGHIKITDFGFAKRVED------------RTFTLCGTPEYLAPE 501 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ S D WALG +F+ML+G PF D + I+ +I+A + FP F +A+DL Sbjct: 502 IIQSKGHGKAVDWWALGILIFEMLAGYPPFYDDDTFAIYNKILAGRITFPLGFDVDAKDL 561 Query: 542 IDKLLDVDPTK 574 I +LL D T+ Sbjct: 562 IKRLLTADRTR 572
>KRAC_DICDI (P54644) RAC-family serine/threonine-protein kinase homolog (EC| 2.7.11.1) Length = 444 Score = 144 bits (363), Expect = 2e-34 Identities = 77/191 (40%), Positives = 113/191 (59%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L ++FQ LY L+ GGELF + + + +ED R+Y AEIV LE+LH Sbjct: 178 PFLVNLNYSFQTEDKLYFILDYVNGGELFYHLQKDKKFTEDRVRYYGAEIVLALEHLHLS 237 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+KPENLLLT++GHI + DFG K + TP ++ TF GT Y+ PE Sbjct: 238 GVIYRDLKPENLLLTNEGHICMTDFGLCKEGLLTP--------TDKTGTFCGTPEYLAPE 289 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 VL D W+ G L++ML+G PF + ++++I+ L FP F S +AR L Sbjct: 290 VLQGNGYGKQVDWWSFGSLLYEMLTGLPPFYNQDVQEMYRKIMMEKLSFPHFISPDARSL 349 Query: 542 IDKLLDVDPTK 574 +++LL+ DP K Sbjct: 350 LEQLLERDPEK 360
>PK2_DICDI (P28178) Protein kinase 2 (EC 2.7.11.1)| Length = 479 Score = 143 bits (360), Expect = 4e-34 Identities = 75/185 (40%), Positives = 107/185 (57%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L + FQ LYM L+ GGELF + R+GR SE + YAAEIV L++LH Sbjct: 211 PFIVNLHYAFQTKDKLYMVLDFVNGGELFFHLKREGRFSEPRVKIYAAEIVSALDHLHKQ 270 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +++RD+KPEN+LL S+GHI I DFG K T + TF GT Y+ PE Sbjct: 271 DIVYRDLKPENILLDSEGHICITDFGLSKKI----------ETTDGTFTFCGTPEYLAPE 320 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 VLN D W+LG L++ML+G PF + ++Q+I+ +L+ P + S EA+ L Sbjct: 321 VLNGHGHGCAVDWWSLGTLLYEMLTGLPPFYSQNVSTMYQKILNGELKIPTYISPEAKSL 380 Query: 542 IDKLL 556 ++ LL Sbjct: 381 LEGLL 385
>KAPC_DROME (P12370) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) (PKA C) Length = 352 Score = 143 bits (360), Expect = 4e-34 Identities = 76/191 (39%), Positives = 110/191 (57%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L + F+D+ +LYM LE GGE+F + + GR SE +RFYAA+IV EYLH + Sbjct: 103 PFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYL 162 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 LI+RD+KPENLL+ S G++K+ DFG K R T GT Y+ PE Sbjct: 163 DLIYRDLKPENLLIDSQGYLKVTDFGFAK------------RVKGRTWTLCGTPEYLAPE 210 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ S D WALG +++M +G PF I+++I++ +RFP F + +DL Sbjct: 211 IILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSDLKDL 270 Query: 542 IDKLLDVDPTK 574 + LL VD TK Sbjct: 271 LRNLLQVDLTK 281
>KAPB_YEAST (P06245) cAMP-dependent protein kinase type 2 (EC 2.7.11.11) (PKA| 2) Length = 380 Score = 142 bits (358), Expect = 7e-34 Identities = 71/191 (37%), Positives = 112/191 (58%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +IR++ TFQD+ +++M ++ EGGELF + + R A+FYAAE++ LEYLH+ Sbjct: 128 PFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAH 187 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +I+RD+KPEN+LL +GHIKI DFG K T GT Y+ PE Sbjct: 188 NIIYRDLKPENILLDRNGHIKITDFGFAK------------EVQTVTWTLCGTPDYIAPE 235 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 V+ + P D W+LG +++ML+G +PF D + +++I+ + +P +F + DL Sbjct: 236 VITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYPPYFHPDVVDL 295 Query: 542 IDKLLDVDPTK 574 + KL+ D T+ Sbjct: 296 LSKLITADLTR 306
>AKT1_CAEEL (Q17941) Serine/threonine-protein kinase akt-1 (EC 2.7.11.1)| (Protein kinase B akt-1) (PKB akt-1) Length = 541 Score = 141 bits (356), Expect = 1e-33 Identities = 79/191 (41%), Positives = 107/191 (56%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + L ++FQ+ + L ++ GGELF + + G SE ARFY AEIV L YLH Sbjct: 251 PFLTELKYSFQEQHYLCFVMQFANGGELFTHVRKCGTFSEPRARFYGAEIVLALGYLHRC 310 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +++RD+K ENLLL DGHIKIADFG K + S ++ TF GT Y+ PE Sbjct: 311 DIVYRDMKLENLLLDKDGHIKIADFGLCKEEI---------SFGDKTSTFCGTPEYLAPE 361 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 VL+ D W +G +++M+ G PF +F+ I+A DLRFP S EAR L Sbjct: 362 VLDDHDYGRCVDWWGVGVVMYEMMCGRLPFYSKDHNKLFELIMAGDLRFPSKLSQEARTL 421 Query: 542 IDKLLDVDPTK 574 + LL DPT+ Sbjct: 422 LTGLLVKDPTQ 432
>KPCD_HUMAN (Q05655) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 676 Score = 141 bits (355), Expect = 2e-33 Identities = 77/191 (40%), Positives = 107/191 (56%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + L TFQ L+ +E GG+L I KGR A FYAAEI+ L++LHS Sbjct: 408 PFLTHLICTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAAEIMCGLQFLHSK 467 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+K +N+LL DGHIKIADFG K + RA TF GT Y+ PE Sbjct: 468 GIIYRDLKLDNVLLDRDGHIKIADFGMCKENI---------FGESRASTFCGTPDYIAPE 518 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 +L TF D W+ G L++ML G SPF E +F+ I +P + + E++D+ Sbjct: 519 ILQGLKYTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDI 578 Query: 542 IDKLLDVDPTK 574 ++KL + +PTK Sbjct: 579 LEKLFEREPTK 589
>KAPC_ASCSU (P49673) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) (PKA C) Length = 337 Score = 140 bits (353), Expect = 3e-33 Identities = 75/191 (39%), Positives = 107/191 (56%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +++++ D Y+LYM E GGELF + S ARFYAAEIV L+YLHS Sbjct: 87 PFIVKMYCASWDKYNLYMLFEYLAGGELFSYLRASRTFSNSMARFYAAEIVCALQYLHSK 146 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 + +RD+KPENL+L +GH+K+ DFG K +D R T GT Y+ PE Sbjct: 147 NIAYRDLKPENLMLNKEGHLKMTDFGFAKEVID------------RTWTMCGTPEYLAPE 194 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 V+ + D W+LG +++M+ G PF+ + I+++II LRF F A+DL Sbjct: 195 VIGNKGHDTAVDWWSLGVLIYEMMIGIPPFRGKTLDEIYEKIILGKLRFTRSFDLFAKDL 254 Query: 542 IDKLLDVDPTK 574 + KLL VD T+ Sbjct: 255 VKKLLQVDRTQ 265
>KS6A_CAEEL (Q21734) Putative ribosomal protein S6 kinase alpha (EC 2.7.11.1)| Length = 784 Score = 140 bits (353), Expect = 3e-33 Identities = 67/184 (36%), Positives = 109/184 (59%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +++L + FQ LY+ L+ GG+LF ++ ++ +ED+ +FY AE+ LE+LHS+ Sbjct: 164 PFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYLAELTLALEHLHSL 223 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+++RD+KPEN+LL +DGHIK+ DFG K +D + ++ +F GT Y+ PE Sbjct: 224 GIVYRDLKPENILLDADGHIKVTDFGLSKEAID---------SEKKTYSFCGTVEYMAPE 274 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 V+N + D W+LG +F+ML+G PF+ +I+ L P F + EA+ L Sbjct: 275 VINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMPHFLTQEAQSL 334 Query: 542 IDKL 553 + L Sbjct: 335 LRAL 338 Score = 104 bits (260), Expect = 2e-22 Identities = 72/201 (35%), Positives = 106/201 (52%), Gaps = 12/201 (5%) Frame = +2 Query: 8 VIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRL-SEDEARFYAAEIVDILEYLHSVG 184 V++LF ++D ++YM E CEGGEL D++V K L SE E A +++ ++YLHS Sbjct: 508 VVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLNAVQYLHSQQ 567 Query: 185 LIHRDVKPENLLLT-SDG---HIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYV 352 + HRD+ N+L DG ++I DFG K + + N T TA +V Sbjct: 568 VAHRDLTAANILFALKDGDPSSLRIVDFGFAKQS---------RAENGMLMTPCYTAQFV 618 Query: 353 PPEVLNSAPATFGNDLWALGCTLFQMLSGSSPF---KDASEWLIFQRI----IARDLRFP 511 PEVL D+W+LG L ML+G +PF + + I QR+ I+ Sbjct: 619 APEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVW 678 Query: 512 EFFSDEARDLIDKLLDVDPTK 574 + SDEA+DL+ K+LDVDP + Sbjct: 679 DTISDEAKDLVRKMLDVDPNR 699
>KPCD_CANFA (Q5PU49) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 674 Score = 140 bits (353), Expect = 3e-33 Identities = 76/191 (39%), Positives = 109/191 (57%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + LF TFQ L+ +E GG+L I KGR A FYAAEIV L++LH+ Sbjct: 406 PFLTHLFCTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAAEIVCGLQFLHNK 465 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+K +N++L DGHIKIADFG K + ++A TF GT Y+ PE Sbjct: 466 GIIYRDLKLDNVMLDQDGHIKIADFGMCKENI---------FGEKQASTFCGTPDYIAPE 516 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 +L +F D W+ G L++ML G SPF E +F+ I +P + + E++D+ Sbjct: 517 ILQGLKYSFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDI 576 Query: 542 IDKLLDVDPTK 574 ++KLL+ D TK Sbjct: 577 LEKLLERDTTK 587
>KS6AA_XENLA (P10665) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 733 Score = 140 bits (352), Expect = 3e-33 Identities = 71/190 (37%), Positives = 112/190 (58%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P V+RL + FQ LY+ L+ GG+LF ++ ++ +E++ +FY AE+ L++LHS+ Sbjct: 122 PFVVRLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSL 181 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+KPEN+LL +GHIK+ DFG K +D ++A +F GT Y+ PE Sbjct: 182 GIIYRDLKPENILLDEEGHIKLTDFGLSKEAID---------HEKKAYSFCGTVEYMAPE 232 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 V+N + D W+ G +F+ML+GS PF+ I+ L P+F S+EA+ L Sbjct: 233 VVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSNEAQSL 292 Query: 542 IDKLLDVDPT 571 + L +PT Sbjct: 293 LRALFKRNPT 302 Score = 95.5 bits (236), Expect = 9e-20 Identities = 69/203 (33%), Positives = 101/203 (49%), Gaps = 12/203 (5%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +I L +++ S+Y+ E GGEL D+I+R+ SE EA + +E LHS Sbjct: 468 PNIIALKDVYKEGNSIYVVTELMRGGELLDRILRQKFFSEREASSVLFTVCKTVENLHSQ 527 Query: 182 GLIHRDVKPENLLLTSDG----HIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAY 349 G++HRD+KP N+L + I+I DFG K + N T TA + Sbjct: 528 GVVHRDLKPSNILYVDESGDPESIRICDFGFAKQL---------RADNGLLMTPCYTANF 578 Query: 350 VPPEVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIAR------DLRFP 511 V PEVL G D+W+LG L+ ML+G +PF + + I+AR LR Sbjct: 579 VAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGLGDTP-EEILARIGSGKFTLRGG 637 Query: 512 EF--FSDEARDLIDKLLDVDPTK 574 + S A+DL+ ++L VDP K Sbjct: 638 NWNTVSAAAKDLVSRMLHVDPHK 660
>KS6A2_HUMAN (Q15349) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (MAP kinase-activated protein kinase 1c) (MAPKAPK1C) Length = 733 Score = 140 bits (352), Expect = 3e-33 Identities = 71/189 (37%), Positives = 111/189 (58%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +++L + FQ LY+ L+ GG+LF ++ ++ +E++ +FY AE+ L++LHS+ Sbjct: 119 PFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSL 178 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+KPEN+LL +GHIKI DFG K +D ++RA +F GT Y+ PE Sbjct: 179 GIIYRDLKPENILLDEEGHIKITDFGLSKEAID---------HDKRAYSFCGTIEYMAPE 229 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 V+N T D W+ G +F+ML+GS PF+ I+ L P+F S EA+ L Sbjct: 230 VVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQSL 289 Query: 542 IDKLLDVDP 568 + L +P Sbjct: 290 LRALFKRNP 298 Score = 100 bits (249), Expect = 3e-21 Identities = 67/200 (33%), Positives = 98/200 (49%), Gaps = 11/200 (5%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +I L + D +Y+ +E GGEL D+I+R+ SE EA I ++YLHS Sbjct: 467 PNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQ 526 Query: 182 GLIHRDVKPENLLLTSDG----HIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAY 349 G++HRD+KP N+L + I++ DFG K + N T TA + Sbjct: 527 GVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQL---------RAGNGLLMTPCYTANF 577 Query: 350 VPPEVLNSAPATFGNDLWALGCTLFQMLSGSSPF---KDASEWLIFQRIIARDLRFP--- 511 V PEVL D+W+LG L+ ML+G +PF D + I RI + Sbjct: 578 VAPEVLKRQGYDAACDIWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGN 637 Query: 512 -EFFSDEARDLIDKLLDVDP 568 + SD A+D++ K+L VDP Sbjct: 638 WDSISDAAKDVVSKMLHVDP 657
>PRKY_HUMAN (O43930) Serine/threonine-protein kinase PRKY (EC 2.7.11.1)| Length = 277 Score = 139 bits (351), Expect = 4e-33 Identities = 75/170 (44%), Positives = 100/170 (58%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +IRLF+T+ + LYM +E GGELF + +G S FY+AEI+ +EYLHS Sbjct: 107 PFLIRLFWTWHEERFLYMLMEYVPGGELFSYLRNRGHFSSTTGLFYSAEIICAIEYLHSK 166 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +++RD+KPEN+LL DGHIK+ DFG K VD R T GT Y+ PE Sbjct: 167 EIVYRDLKPENILLDRDGHIKLTDFGFAKKLVD------------RTWTLCGTPEYLAPE 214 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFP 511 V+ S D WALG +F+MLSG PF D + + I+Q+I+A L FP Sbjct: 215 VIQSKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKLYFP 264
>PHOT2_ARATH (P93025) Phototropin-2 (EC 2.7.11.1) (Defective in chloroplast| avoidance protein 1) (Non phototropic hypocotyl 1-like protein 1) (NPH1-like 1) (AtKin7) Length = 915 Score = 139 bits (351), Expect = 4e-33 Identities = 83/212 (39%), Positives = 120/212 (56%), Gaps = 22/212 (10%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGR--LSEDEARFYAAEIVDILEYLH 175 P + L+ +FQ S + + + C GGELF + R+ L+ED ARFYAAE+V LEYLH Sbjct: 635 PFLPTLYASFQTSTHVCLITDFCPGGELFALLDRQPMKILTEDSARFYAAEVVIGLEYLH 694 Query: 176 SVGLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNER------------ 319 +G+++RD+KPEN+LL DGHI +ADF T TP ++P + ++R Sbjct: 695 CLGIVYRDLKPENILLKKDGHIVLADFDLSFMTTCTPQLIIPAAPSKRRRSKSQPLPTFV 754 Query: 320 ------ACTFVGTAAYVPPEVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQ 481 + +FVGT Y+ PE++ A T D WALG L++ML G +PF+ + F Sbjct: 755 AEPSTQSNSFVGTEEYIAPEIITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRQKTFA 814 Query: 482 RIIARDLRFPEFF--SDEARDLIDKLLDVDPT 571 I+ +DL FP S R LI+ LL+ DP+ Sbjct: 815 NILHKDLTFPSSIPVSLVGRQLINTLLNRDPS 846
>KIN82_YEAST (P25341) Probable serine/threonine-protein kinase KIN82 (EC| 2.7.11.1) Length = 720 Score = 139 bits (351), Expect = 4e-33 Identities = 80/204 (39%), Positives = 120/204 (58%), Gaps = 13/204 (6%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQI-VRKGR-LSEDEARFYAAEIVDILEYLH 175 P ++ L+ +FQ LY+ +E C GGE F + RK + ++E++A+FYA+E+V LEYLH Sbjct: 382 PFIVTLYHSFQTKDYLYLCMEYCMGGEFFRALQTRKSKCIAEEDAKFYASEVVAALEYLH 441 Query: 176 SVGLIHRDVKPENLLLTSDGHIKIADF-------GSVKPTV--DTPIKVLPNSTNERACT 328 +G I+RD+KPEN+LL GH+ ++DF GS KPT+ T + S R + Sbjct: 442 LLGFIYRDLKPENILLHQSGHVMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRTNS 501 Query: 329 FVGTAAYVPPEVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRF 508 FVGT Y+ PEV+ T D W LG +++ML G +PFK + F I+ +D++F Sbjct: 502 FVGTEEYLAPEVIRGNGHTAAVDWWTLGILIYEMLFGCTPFKGDNSNETFSNILTKDVKF 561 Query: 509 P--EFFSDEARDLIDKLLDVDPTK 574 P + S +DLI KLL+ + K Sbjct: 562 PHDKEVSKNCKDLIKKLLNKNEAK 585
>PKH3_YEAST (Q03306) Serine/threonine-protein kinase PKH3 (EC 2.7.11.1)| (Pkb-activating kinase homolog 3) Length = 898 Score = 139 bits (351), Expect = 4e-33 Identities = 69/174 (39%), Positives = 107/174 (61%), Gaps = 9/174 (5%) Frame = +2 Query: 5 GVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSVG 184 G+I+L++TF D +LY L+ GGEL + + G ++ R + A+++D LE++HS G Sbjct: 74 GIIKLYYTFHDEENLYFVLDFAPGGELLSLLHKMGTFNDIWTRHFTAQLIDALEFIHSHG 133 Query: 185 LIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPI-----KVLPNST----NERACTFVG 337 +IHRD+KPEN+LL DG + I DFG+ T+D + K +S N+ +FVG Sbjct: 134 IIHRDLKPENVLLDRDGRLMITDFGAA-ATIDPSLSGDSAKFNSDSNGSKDNQNCASFVG 192 Query: 338 TAAYVPPEVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARD 499 TA YV PE+L +G+D+WALGC ++Q + G PF+ +E F++I+A D Sbjct: 193 TAEYVSPELLLYNQCGYGSDIWALGCMIYQFVQGQPPFRGENELKTFEKIVALD 246
>KS6AB_XENLA (P10666) Ribosomal protein S6 kinase 2 beta (EC 2.7.11.1)| (Ribosomal protein S6 kinase II beta) (S6KII-beta) (P90-RSK) Length = 629 Score = 139 bits (350), Expect = 6e-33 Identities = 71/190 (37%), Positives = 112/190 (58%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P V+RL + FQ LY+ L+ GG+LF ++ ++ +E++ +FY AE+ L++LHS+ Sbjct: 122 PFVVRLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSL 181 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+KPEN+LL +GHIK+ DFG K +D ++A +F GT Y+ PE Sbjct: 182 GIIYRDLKPENILLDEEGHIKLTDFGLSKEAID---------HEKKAYSFCGTVEYMAPE 232 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 V+N + G D W+ G +F+ML+GS PF+ I+ L P+F S+EA+ L Sbjct: 233 VVNRQGHSHGADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSNEAQSL 292 Query: 542 IDKLLDVDPT 571 + L + T Sbjct: 293 LRALFKRNAT 302 Score = 92.8 bits (229), Expect = 6e-19 Identities = 56/154 (36%), Positives = 80/154 (51%), Gaps = 4/154 (2%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +I L +++ S+Y+ E GGEL D+I+R+ SE EA + +EYLHS Sbjct: 468 PNIITLKDVYEECNSIYLVTELMRGGELLDRILRQKFFSEREACSVLFTVCKTVEYLHSQ 527 Query: 182 GLIHRDVKPENLLLTSDG----HIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAY 349 G++HRD+KP N+L + I+I DFG K + N T TA + Sbjct: 528 GVVHRDLKPSNILYVDESGDPESIRICDFGFSKQL---------RAENGLLMTPCYTANF 578 Query: 350 VPPEVLNSAPATFGNDLWALGCTLFQMLSGSSPF 451 V PEVL G D+W+LG L+ ML+G +PF Sbjct: 579 VAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPF 612
>KAPCG_HUMAN (P22612) cAMP-dependent protein kinase, gamma-catalytic subunit (EC| 2.7.11.11) (PKA C-gamma) Length = 350 Score = 139 bits (349), Expect = 7e-33 Identities = 73/191 (38%), Positives = 110/191 (57%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +++L F+F+D+ LY+ +E GGE+F ++ R GR SE A FYAA++V ++YLHS+ Sbjct: 101 PFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSL 160 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 LIHRD+KPENLL+ G++++ DFG K R T GT Y+ PE Sbjct: 161 DLIHRDLKPENLLIDQQGYLQVTDFGFAK------------RVKGRTWTLCGTPEYLAPE 208 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ S D WALG +++M G PF I+++I++ +RFP S + + L Sbjct: 209 IILSKGYNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSDLKHL 268 Query: 542 IDKLLDVDPTK 574 + LL VD TK Sbjct: 269 LRSLLQVDLTK 279
>KDC2_DROME (P16912) Protein kinase DC2 (EC 2.7.11.1)| Length = 583 Score = 138 bits (348), Expect = 1e-32 Identities = 75/191 (39%), Positives = 107/191 (56%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P VI L ++ +D +LYM + GGELF + G+ + + FYAAEIV LEYLHS+ Sbjct: 332 PFVISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGKFTSQTSNFYAAEIVSALEYLHSL 391 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +++RD+KPENLL+ DGH+KI DFG K +R T GT Y+ PE Sbjct: 392 QIVYRDLKPENLLINRDGHLKITDFGFAK------------KLRDRTWTLCGTPEYIAPE 439 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ S D WALG +++ML G PF D + I+++I++ + + A+DL Sbjct: 440 IIQSKGHNKAVDWWALGVLIYEMLVGYPPFYDEQPFGIYEKILSGKIEWERHMDPIAKDL 499 Query: 542 IDKLLDVDPTK 574 I KLL D TK Sbjct: 500 IKKLLVNDRTK 510
>KAPB_SCHPO (P40376) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) Length = 512 Score = 138 bits (347), Expect = 1e-32 Identities = 71/190 (37%), Positives = 108/190 (56%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + L+ TFQD+ +L+M ++ EGGELF + + R E A+FYAAE++ L+YLH Sbjct: 259 PFITILWGTFQDAKNLFMVMDFAEGGELFSLLRKCHRFPEKVAKFYAAEVILALDYLHHN 318 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +++RD+KPENLLL GH+KI DFG K + CT GT Y+ PE Sbjct: 319 QIVYRDLKPENLLLDRFGHLKIVDFGFAK-----------RVSTSNCCTLCGTPDYLAPE 367 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 +++ P D W+LG +F+ML+G PF + +++ I+ + +P +FS + DL Sbjct: 368 IISLKPYNKAADWWSLGILIFEMLAGYPPFYSENPMKLYENILEGKVNYPSYFSPASIDL 427 Query: 542 IDKLLDVDPT 571 + LL D T Sbjct: 428 LSHLLQRDIT 437
>KS6A1_RAT (Q63531) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 137 bits (346), Expect = 2e-32 Identities = 70/189 (37%), Positives = 110/189 (58%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P V++L + FQ LY+ L+ GG+LF ++ ++ +E++ +FY AE+ L++LHS+ Sbjct: 122 PFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSL 181 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+KPEN+LL +GHIK+ DFG K +D ++A +F GT Y+ PE Sbjct: 182 GIIYRDLKPENILLDEEGHIKLTDFGLSKEAID---------HEKKAYSFCGTVEYMAPE 232 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 V+N T D W+ G +F+ML+GS PF+ I+ L P+F S EA+ L Sbjct: 233 VVNRQGHTHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSTEAQSL 292 Query: 542 IDKLLDVDP 568 + L +P Sbjct: 293 LRALFKRNP 301 Score = 103 bits (258), Expect = 3e-22 Identities = 70/200 (35%), Positives = 99/200 (49%), Gaps = 11/200 (5%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +I L + DS +Y+ E GGEL D+I+R+ SE EA F I +EYLHS Sbjct: 470 PNIITLKDVYDDSKHVYLVTELMRGGELLDKILRQKFFSEREASFVLYTISKTVEYLHSQ 529 Query: 182 GLIHRDVKPENLLLTSDGH----IKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAY 349 G++HRD+KP N+L + ++I DFG K + N T TA + Sbjct: 530 GVVHRDLKPSNILYVDESGNPECLRICDFGFAKQL---------RAENGLLMTPCYTANF 580 Query: 350 VPPEVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDA---SEWLIFQRIIARDLRFP--- 511 V PEVL G D+W+LG L+ ML+G +PF + + I RI + Sbjct: 581 VAPEVLKRQGYDEGCDIWSLGVLLYTMLAGYTPFANGPSDTPEEILTRISSGKFTLSGGN 640 Query: 512 -EFFSDEARDLIDKLLDVDP 568 S+ A+DL+ K+L VDP Sbjct: 641 WNTVSETAKDLVSKMLHVDP 660
>KS6A3_MOUSE (P18654) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B) Length = 740 Score = 137 bits (346), Expect = 2e-32 Identities = 68/189 (35%), Positives = 111/189 (58%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +++L + FQ LY+ L+ GG+LF ++ ++ +E++ +FY AE+ L++LHS+ Sbjct: 128 PFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSL 187 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+KPEN+LL +GHIK+ DFG K ++D ++A +F GT Y+ PE Sbjct: 188 GIIYRDLKPENILLDEEGHIKLTDFGLSKESID---------HEKKAYSFCGTVEYMAPE 238 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 V+N T D W+ G +F+ML+G+ PF+ I+ L P+F S EA+ L Sbjct: 239 VVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSL 298 Query: 542 IDKLLDVDP 568 + L +P Sbjct: 299 LRMLFKRNP 307 Score = 100 bits (248), Expect = 4e-21 Identities = 69/200 (34%), Positives = 98/200 (49%), Gaps = 11/200 (5%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +I L + D +Y+ E +GGEL D+I+R+ SE EA I +EYLH+ Sbjct: 474 PNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQ 533 Query: 182 GLIHRDVKPENLLLTSDG----HIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAY 349 G++HRD+KP N+L + I+I DFG K + N T TA + Sbjct: 534 GVVHRDLKPSNILYVDESGNPESIRICDFGFAKQL---------RAENGLLMTPCYTANF 584 Query: 350 VPPEVLNSAPATFGNDLWALGCTLFQMLSGSSPF---KDASEWLIFQRIIARDLRFPEFF 520 V PEVL D+W+LG L+ ML+G +PF D + I RI + + Sbjct: 585 VAPEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGY 644 Query: 521 ----SDEARDLIDKLLDVDP 568 SD A+DL+ K+L VDP Sbjct: 645 WNSVSDTAKDLVSKMLHVDP 664
>KS6A3_HUMAN (P51812) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protei Length = 740 Score = 137 bits (346), Expect = 2e-32 Identities = 68/189 (35%), Positives = 111/189 (58%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +++L + FQ LY+ L+ GG+LF ++ ++ +E++ +FY AE+ L++LHS+ Sbjct: 128 PFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSL 187 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+KPEN+LL +GHIK+ DFG K ++D ++A +F GT Y+ PE Sbjct: 188 GIIYRDLKPENILLDEEGHIKLTDFGLSKESID---------HEKKAYSFCGTVEYMAPE 238 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 V+N T D W+ G +F+ML+G+ PF+ I+ L P+F S EA+ L Sbjct: 239 VVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSL 298 Query: 542 IDKLLDVDP 568 + L +P Sbjct: 299 LRMLFKRNP 307 Score = 100 bits (248), Expect = 4e-21 Identities = 69/200 (34%), Positives = 98/200 (49%), Gaps = 11/200 (5%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +I L + D +Y+ E +GGEL D+I+R+ SE EA I +EYLH+ Sbjct: 474 PNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQ 533 Query: 182 GLIHRDVKPENLLLTSDG----HIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAY 349 G++HRD+KP N+L + I+I DFG K + N T TA + Sbjct: 534 GVVHRDLKPSNILYVDESGNPESIRICDFGFAKQL---------RAENGLLMTPCYTANF 584 Query: 350 VPPEVLNSAPATFGNDLWALGCTLFQMLSGSSPF---KDASEWLIFQRIIARDLRFPEFF 520 V PEVL D+W+LG L+ ML+G +PF D + I RI + + Sbjct: 585 VAPEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGY 644 Query: 521 ----SDEARDLIDKLLDVDP 568 SD A+DL+ K+L VDP Sbjct: 645 WNSVSDTAKDLVSKMLHVDP 664
>KS6B2_HUMAN (Q9UBS0) Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K2)| (70 kDa ribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase beta) (p70 S6Kbeta) (p70 S6 kinase beta) (S6K-beta) (p70-beta) (S6 kinase-related kinase) (SRK) (Serin Length = 482 Score = 137 bits (346), Expect = 2e-32 Identities = 77/193 (39%), Positives = 108/193 (55%), Gaps = 2/193 (1%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L + FQ LY+ LE GGELF + R+G ED A FY AEI L +LHS Sbjct: 129 PFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLHSQ 188 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERAC--TFVGTAAYVP 355 G+I+RD+KPEN++L+S GHIK+ DFG K S +E A TF GT Y+ Sbjct: 189 GIIYRDLKPENIMLSSQGHIKLTDFGLCK-----------ESIHEGAVTHTFCGTIEYMA 237 Query: 356 PEVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEAR 535 PE+L + D W+LG ++ ML+GS PF + +II L P + + +AR Sbjct: 238 PEILVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDAR 297 Query: 536 DLIDKLLDVDPTK 574 DL+ K L +P++ Sbjct: 298 DLVKKFLKRNPSQ 310
>KPCD_MOUSE (P28867) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 674 Score = 137 bits (346), Expect = 2e-32 Identities = 75/191 (39%), Positives = 106/191 (55%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + L TFQ L+ +E GG+L I KGR A FYAAEI+ L++LHS Sbjct: 406 PFLTHLICTFQTKDHLFFVMEFLNGGDLMFHIQDKGRFELYRATFYAAEIICGLQFLHSK 465 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+K +N++L DGHIKIADFG K + RA TF GT Y+ PE Sbjct: 466 GIIYRDLKLDNVMLDRDGHIKIADFGMCKENI---------FGEGRASTFCGTPDYIAPE 516 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 +L +F D W+ G L++ML G SPF E +F+ I +P + + E++D+ Sbjct: 517 ILQGLKYSFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDI 576 Query: 542 IDKLLDVDPTK 574 ++KL + DP K Sbjct: 577 MEKLFERDPDK 587
>KPCD_RAT (P09215) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 673 Score = 137 bits (346), Expect = 2e-32 Identities = 74/191 (38%), Positives = 105/191 (54%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + L TFQ L+ +E GG+L I KGR A FYAAEI+ L++LH Sbjct: 406 PFLTHLICTFQTKDHLFFVMEFLNGGDLMFHIQDKGRFELYRATFYAAEIICGLQFLHGK 465 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+K +N++L DGHIKIADFG K + RA TF GT Y+ PE Sbjct: 466 GIIYRDLKLDNVMLDKDGHIKIADFGMCKENI---------FGENRASTFCGTPDYIAPE 516 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 +L +F D W+ G L++ML G SPF E +F+ I +P + + E++D+ Sbjct: 517 ILQGLKYSFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDI 576 Query: 542 IDKLLDVDPTK 574 ++KL + DP K Sbjct: 577 MEKLFERDPAK 587
>KS6A2_MOUSE (Q9WUT3) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (Protein-tyrosine kinase Mpk-9) (MAP kinase-activated protein kinase 1c) (M Length = 733 Score = 137 bits (344), Expect = 3e-32 Identities = 70/189 (37%), Positives = 109/189 (57%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +++L + FQ LY+ L+ GG+LF ++ ++ +E++ +FY AE+ L++LH + Sbjct: 119 PFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHGL 178 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+KPEN+LL +GHIKI DFG K D ++RA +F GT Y+ PE Sbjct: 179 GIIYRDLKPENILLDEEGHIKITDFGLSKEATD---------HDKRAYSFCGTIEYMAPE 229 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 V+N T D W+ G +F+ML+GS PF+ I+ L P+F S EA+ L Sbjct: 230 VVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSAEAQSL 289 Query: 542 IDKLLDVDP 568 + L +P Sbjct: 290 LRALFKRNP 298 Score = 99.4 bits (246), Expect = 7e-21 Identities = 68/200 (34%), Positives = 98/200 (49%), Gaps = 11/200 (5%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +I L + D +Y+ +E GGEL D+I+R+ SE EA I ++YLHS Sbjct: 467 PNIITLKDVYDDGKYVYLVMELMRGGELLDRILRQRCFSEREASDVLYTIARTMDYLHSQ 526 Query: 182 GLIHRDVKPENLLLTSDG----HIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAY 349 G++HRD+KP N+L + I+I DFG K + N T TA + Sbjct: 527 GVVHRDLKPSNILYMDESGNPESIRICDFGFAKQL---------RAENGLLMTPCYTANF 577 Query: 350 VPPEVLNSAPATFGNDLWALGCTLFQMLSGSSPF---KDASEWLIFQRIIARDLRFP--- 511 V PEVL D+W+LG L+ ML+G +PF D + I RI + Sbjct: 578 VAPEVLKRQGYDAACDVWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGN 637 Query: 512 -EFFSDEARDLIDKLLDVDP 568 + SD A+D++ K+L VDP Sbjct: 638 WDSISDAAKDVVSKMLHVDP 657
>KPK1_ARATH (P42818) Serine/threonine-protein kinase AtPK1/AtPK6 (EC 2.7.11.1)| Length = 465 Score = 137 bits (344), Expect = 3e-32 Identities = 69/191 (36%), Positives = 110/191 (57%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +++L ++FQ Y LY+ L+ GG LF Q+ +G ED AR Y AEIV + +LH Sbjct: 192 PFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHEK 251 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G++HRD+KPEN+L+ +DGH+ + DFG K + N R+ + GT Y+ PE Sbjct: 252 GIMHRDLKPENILMDTDGHVMLTDFGLAKEFEE----------NTRSNSMCGTTEYMAPE 301 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ D W++G L++ML+G PF S+ I Q+I+ ++ P+F S+EA + Sbjct: 302 IVRGKGHDKAADWWSVGILLYEMLTGKPPFL-GSKGKIQQKIVKDKIKLPQFLSNEAHAI 360 Query: 542 IDKLLDVDPTK 574 + LL +P + Sbjct: 361 LKGLLQKEPER 371
>KPK19_ARATH (Q39030) Serine/threonine-protein kinase AtPK19 (EC 2.7.11.1)| (Ribosomal-protein S6 kinase homolog) Length = 471 Score = 136 bits (343), Expect = 4e-32 Identities = 70/191 (36%), Positives = 109/191 (57%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +++L ++FQ Y LY+ L+ GG LF Q+ +G ED AR Y AEIV + +LH Sbjct: 198 PFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHEK 257 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G++HRD+KPEN+L+ DGH+ + DFG K + N R+ + GT Y+ PE Sbjct: 258 GIMHRDLKPENILMDVDGHVMLTDFGLAKEFEE----------NTRSNSMCGTTEYMAPE 307 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ D W++G L++ML+G PF S+ I Q+I+ ++ P+F S+EA L Sbjct: 308 IVRGKGHDKAADWWSVGILLYEMLTGKPPFL-GSKGKIQQKIVKDKIKLPQFLSNEAHAL 366 Query: 542 IDKLLDVDPTK 574 + LL +P + Sbjct: 367 LKGLLQKEPER 377
>SGK1_HUMAN (O00141) Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 1) Length = 431 Score = 136 bits (343), Expect = 4e-32 Identities = 75/191 (39%), Positives = 105/191 (54%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L F+FQ + LY L+ GGELF + R+ E ARFYAAEI L YLHS+ Sbjct: 157 PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSL 216 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +++RD+KPEN+LL S GHI + DFG K ++ N TF GT Y+ PE Sbjct: 217 NIVYRDLKPENILLDSQGHIVLTDFGLCKENIE---------HNSTTSTFCGTPEYLAPE 267 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 VL+ P D W LG L++ML G PF + ++ I+ + L+ ++ AR L Sbjct: 268 VLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHL 327 Query: 542 IDKLLDVDPTK 574 ++ LL D TK Sbjct: 328 LEGLLQKDRTK 338
>AKT2A_XENLA (Q7ZX15) RAC-beta serine/threonine-protein kinase-A (EC 2.7.11.1)| (RAC-PK-beta-A) (Protein kinase Akt-2-A) (Protein kinase B, beta-A) (PKB beta-A) Length = 486 Score = 136 bits (342), Expect = 5e-32 Identities = 75/189 (39%), Positives = 102/189 (53%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + L + FQ S L +E GGELF + R+ +ED ARFY AEIV LEYLHS Sbjct: 215 PFLTALKYAFQTSDRLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIVSALEYLHSR 274 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +++RD+K ENL+L DGH+KI DFG K + + TF GT Y+ PE Sbjct: 275 NVVYRDIKLENLMLDKDGHVKITDFGLCKEGI---------TDGATMRTFCGTPEYLAPE 325 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 VL D W LG +++M+ G PF + +F+ I+ ++RFP S EA+ L Sbjct: 326 VLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSL 385 Query: 542 IDKLLDVDP 568 + LL DP Sbjct: 386 LAGLLKKDP 394
>KS6A1_HUMAN (Q15418) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 136 bits (342), Expect = 5e-32 Identities = 69/189 (36%), Positives = 110/189 (58%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P V++L + FQ LY+ L+ GG+LF ++ ++ +E++ +FY AE+ L++LHS+ Sbjct: 122 PFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSL 181 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+KPEN+LL +GHIK+ DFG K +D ++A +F GT Y+ PE Sbjct: 182 GIIYRDLKPENILLDEEGHIKLTDFGLSKEAID---------HEKKAYSFCGTVEYMAPE 232 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 V+N + D W+ G +F+ML+GS PF+ I+ L P+F S EA+ L Sbjct: 233 VVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSTEAQSL 292 Query: 542 IDKLLDVDP 568 + L +P Sbjct: 293 LRALFKRNP 301 Score = 101 bits (251), Expect = 2e-21 Identities = 69/200 (34%), Positives = 98/200 (49%), Gaps = 11/200 (5%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +I L + D +Y+ E GGEL D+I+R+ SE EA F I +EYLHS Sbjct: 470 PNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTIGKTVEYLHSQ 529 Query: 182 GLIHRDVKPENLLLTSDGH----IKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAY 349 G++HRD+KP N+L + ++I DFG K + N T TA + Sbjct: 530 GVVHRDLKPSNILYVDESGNPECLRICDFGFAKQL---------RAENGLLMTPCYTANF 580 Query: 350 VPPEVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDA---SEWLIFQRIIARDLRFP--- 511 V PEVL G D+W+LG L+ ML+G +PF + + I RI + Sbjct: 581 VAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTLSGGN 640 Query: 512 -EFFSDEARDLIDKLLDVDP 568 S+ A+DL+ K+L VDP Sbjct: 641 WNTVSETAKDLVSKMLHVDP 660
>KS6B2_MOUSE (Q9Z1M4) Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K-beta| 2) (70 kDa ribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase beta) (p70 S6Kbeta) (S6K2) Length = 485 Score = 136 bits (342), Expect = 5e-32 Identities = 78/193 (40%), Positives = 106/193 (54%), Gaps = 2/193 (1%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L + FQ LY+ LE GGELF + R+G ED A FY AEI L +LHS Sbjct: 129 PFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLHSH 188 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERAC--TFVGTAAYVP 355 G+I+RD+KPEN++L+S GHIK+ DFG K S +E A TF GT Y+ Sbjct: 189 GIIYRDLKPENIMLSSQGHIKLTDFGLCK-----------ESIHEGAITHTFCGTIEYMA 237 Query: 356 PEVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEAR 535 PE+L D W+LG ++ ML+GS PF + +II L P + + +AR Sbjct: 238 PEILVRTGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIKGKLVLPPYLTPDAR 297 Query: 536 DLIDKLLDVDPTK 574 DL K L +PT+ Sbjct: 298 DLAKKFLKRNPTQ 310
>SGK1_RABIT (Q9XT18) Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 1) Length = 431 Score = 135 bits (341), Expect = 6e-32 Identities = 75/191 (39%), Positives = 105/191 (54%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L F+FQ + LY L+ GGELF + R+ E ARFYAAEI L YLHS+ Sbjct: 157 PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSL 216 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +++RD+KPEN+LL S GHI + DFG K ++ N TF GT Y+ PE Sbjct: 217 NIVYRDLKPENILLDSQGHIVLTDFGLCKENIE---------HNGTTSTFCGTPEYLAPE 267 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 VL+ P D W LG L++ML G PF + ++ I+ + L+ ++ AR L Sbjct: 268 VLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHL 327 Query: 542 IDKLLDVDPTK 574 ++ LL D TK Sbjct: 328 LEGLLQKDRTK 338
>SGK1_MOUSE (Q9WVC6) Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 1) Length = 431 Score = 135 bits (341), Expect = 6e-32 Identities = 75/191 (39%), Positives = 105/191 (54%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L F+FQ + LY L+ GGELF + R+ E ARFYAAEI L YLHS+ Sbjct: 157 PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSL 216 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +++RD+KPEN+LL S GHI + DFG K ++ N TF GT Y+ PE Sbjct: 217 NIVYRDLKPENILLDSQGHIVLTDFGLCKENIE---------HNGTTSTFCGTPEYLAPE 267 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 VL+ P D W LG L++ML G PF + ++ I+ + L+ ++ AR L Sbjct: 268 VLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHL 327 Query: 542 IDKLLDVDPTK 574 ++ LL D TK Sbjct: 328 LEGLLQKDRTK 338
>NRC2_NEUCR (O42626) Serine/threonine-protein kinase nrc-2 (EC 2.7.11.1)| (Nonrepressible conidiation protein 2) Length = 623 Score = 135 bits (341), Expect = 6e-32 Identities = 81/220 (36%), Positives = 116/220 (52%), Gaps = 29/220 (13%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQI-VRKGR-LSEDEARFYAAEIVDILEYLH 175 P ++ L+ +FQ LY+ +E C GGE F + R G+ + ED+ARFYAAE+ LEYLH Sbjct: 300 PFIVTLYHSFQSEDYLYLCMEYCSGGEFFRALQTRPGKCIPEDDARFYAAEVTAALEYLH 359 Query: 176 SVGLIHRDVKPENLLLTSDGHIKIADFGSVK----------------------PTVDTPI 289 +G I+RD+KPEN+LL GHI ++DF K PT+DT Sbjct: 360 LMGFIYRDLKPENILLHQSGHIMLSDFDLSKQSDPGGKPTMIIGKNGTSTSSLPTIDTKS 419 Query: 290 KVLPNSTNERACTFVGTAAYVPPEVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEW 469 + N R +FVGT Y+ PEV+ + T D W LG +++ML G++PFK + Sbjct: 420 CI----ANFRTNSFVGTEEYIAPEVIKGSGHTSAVDWWTLGILIYEMLYGTTPFKGKNRN 475 Query: 470 LIFQRIIARDLRFPEF-----FSDEARDLIDKLLDVDPTK 574 F I+ D+ FP+ S+ + LI KLL D + Sbjct: 476 ATFANILREDIPFPDHAGAPQISNLCKSLIRKLLIKDENR 515
>KS6AA_CHICK (P18652) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 752 Score = 135 bits (341), Expect = 6e-32 Identities = 69/189 (36%), Positives = 110/189 (58%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P V++L + FQ LY+ L+ GG+LF ++ ++ +E++ +FY AE+ L++LHS+ Sbjct: 140 PFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSL 199 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+KPEN+LL +GHIK+ DFG K +D ++A +F GT Y+ PE Sbjct: 200 GIIYRDLKPENILLDEEGHIKLTDFGLSKEAID---------HEKKAYSFCGTVEYMAPE 250 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 V+N + D W+ G +F+ML+GS PF+ I+ L P+F S EA+ L Sbjct: 251 VVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSAEAQSL 310 Query: 542 IDKLLDVDP 568 + L +P Sbjct: 311 LRALFKRNP 319 Score = 101 bits (251), Expect = 2e-21 Identities = 70/200 (35%), Positives = 97/200 (48%), Gaps = 11/200 (5%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +I L + D +Y+ E GGEL D+I+R+ SE EA I +EYLHS Sbjct: 487 PNIITLKDVYDDGKYVYLVTELMRGGELLDKILRQKFFSEREASSVLHTICKTVEYLHSQ 546 Query: 182 GLIHRDVKPENLLLTSDG----HIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAY 349 G++HRD+KP N+L + I+I DFG K + N T TA + Sbjct: 547 GVVHRDLKPSNILYVDESGNPESIRICDFGFAKQL---------RAENGLLMTPCYTANF 597 Query: 350 VPPEVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDA---SEWLIFQRIIARDLRFP--- 511 V PEVL G D+W+LG L+ ML+G +PF + + I RI Sbjct: 598 VAPEVLKRQGYDEGCDIWSLGVLLYTMLAGCTPFANGPSDTPEEILTRIGGGKFSVNGGN 657 Query: 512 -EFFSDEARDLIDKLLDVDP 568 + SD A+DL+ K+L VDP Sbjct: 658 WDTISDVAKDLVSKMLHVDP 677
>YPK2_YEAST (P18961) Serine/threonine-protein kinase YPK2/YKR2 (EC 2.7.11.1)| Length = 677 Score = 134 bits (338), Expect = 1e-31 Identities = 72/191 (37%), Positives = 110/191 (57%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L F+FQ LY+ L GGELF + +GR S +RFY AE++ L+ LH + Sbjct: 402 PFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHEGRFSLARSRFYIAELLCALDSLHKL 461 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +I+RD+KPEN+LL GHI + DFG K L N++ TF GT Y+ PE Sbjct: 462 DVIYRDLKPENILLDYQGHIALCDFGLCK---------LNMKDNDKTDTFCGTPEYLAPE 512 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 +L T D W LG L++M++G P+ D + +++++I+ + L FP+ F A+DL Sbjct: 513 ILLGQGYTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKILQQPLLFPDGFDPAAKDL 572 Query: 542 IDKLLDVDPTK 574 + LL DP++ Sbjct: 573 LIGLLSRDPSR 583
>AKT2B_XENLA (Q6IP76) RAC-beta serine/threonine-protein kinase-B (EC 2.7.11.1)| (RAC-PK-beta-B) (Protein kinase Akt-2-B) (Protein kinase B, beta-B) (PKB beta-B) Length = 485 Score = 134 bits (338), Expect = 1e-31 Identities = 75/189 (39%), Positives = 101/189 (53%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + L + FQ S L +E GGELF + R+ +ED ARFY AEIV LEYLHS Sbjct: 214 PFLTGLKYAFQTSDRLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIVSALEYLHSR 273 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +++RD+K ENL+L DGH+KI DFG K + + TF GT Y+ PE Sbjct: 274 NVVYRDIKLENLMLDKDGHVKITDFGLCKEGI---------TDGATMRTFCGTPEYLAPE 324 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 VL D W LG +++M+ G PF + +F+ I+ + RFP S EA+ L Sbjct: 325 VLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEETRFPRTLSPEAKSL 384 Query: 542 IDKLLDVDP 568 + LL DP Sbjct: 385 LAGLLKKDP 393
>AKT1_DROME (Q8INB9) RAC serine/threonine-protein kinase (EC 2.7.11.1)| (DRAC-PK) (Akt) (Dakt1) (Protein kinase B) (PKB) Length = 611 Score = 134 bits (337), Expect = 2e-31 Identities = 73/191 (38%), Positives = 106/191 (55%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +I L ++FQ + L ++ GGELF + + +ED RFY AEI+ L YLHS Sbjct: 324 PFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGAEIISALGYLHSQ 383 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+K ENLLL DGHIK+ADFG K + + TF GT Y+ PE Sbjct: 384 GIIYRDLKLENLLLDKDGHIKVADFGLCKEDI---------TYGRTTKTFCGTPEYLAPE 434 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 VL+ D W G +++M+ G PF + ++F I+ +++FP +DEA++L Sbjct: 435 VLDDNDYGQAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEEVKFPRNITDEAKNL 494 Query: 542 IDKLLDVDPTK 574 + LL DP K Sbjct: 495 LAGLLAKDPKK 505
>AKT3_RAT (Q63484) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) Length = 454 Score = 134 bits (336), Expect = 2e-31 Identities = 74/191 (38%), Positives = 102/191 (53%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + L ++FQ L +E GGELF + R+ SED RFY AEIV L+YLHS Sbjct: 206 PFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSG 265 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +++RD+K ENL+L DGHIKI DFG K + + TF GT Y+ PE Sbjct: 266 KIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMK---------TFCGTPEYLAPE 316 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 VL D W LG +++M+ G PF + +F+ I+ D++FP S +A+ L Sbjct: 317 VLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSL 376 Query: 542 IDKLLDVDPTK 574 + LL DP K Sbjct: 377 LSGLLIKDPNK 387
>YPK1_YEAST (P12688) Serine/threonine-protein kinase YPK1 (EC 2.7.11.1)| Length = 680 Score = 134 bits (336), Expect = 2e-31 Identities = 72/191 (37%), Positives = 107/191 (56%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L F+FQ LY L GGELF + ++GR ARFY AE++ L+ LH + Sbjct: 405 PFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLHKL 464 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +++RD+KPEN+LL GHI + DFG K L +++ TF GT Y+ PE Sbjct: 465 DVVYRDLKPENILLDYQGHIALCDFGLCK---------LNMKDDDKTDTFCGTPEYLAPE 515 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 +L T D W LG L++ML+G P+ D ++++I+ L FP+ F +A+DL Sbjct: 516 LLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQEPLVFPDGFDRDAKDL 575 Query: 542 IDKLLDVDPTK 574 + LL DPT+ Sbjct: 576 LIGLLSRDPTR 586
>AKT2_MOUSE (Q60823) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 134 bits (336), Expect = 2e-31 Identities = 75/189 (39%), Positives = 100/189 (52%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + L + FQ L +E GGELF + R+ +ED ARFY AEIV LEYLHS Sbjct: 210 PFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIVSALEYLHSR 269 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +++RD+K ENL+L DGHIKI DFG K + S TF GT Y+ PE Sbjct: 270 DVVYRDIKLENLMLDKDGHIKITDFGLCKEGI---------SDGATMKTFCGTPEYLAPE 320 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 VL D W LG +++M+ G PF + +F+ I+ ++RFP EA+ L Sbjct: 321 VLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLGPEAKSL 380 Query: 542 IDKLLDVDP 568 + LL DP Sbjct: 381 LAGLLKKDP 389
>AKT2_HUMAN (P31751) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 134 bits (336), Expect = 2e-31 Identities = 75/189 (39%), Positives = 101/189 (53%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + L + FQ L +E GGELF + R+ +E+ ARFY AEIV LEYLHS Sbjct: 210 PFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLHSR 269 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +++RD+K ENL+L DGHIKI DFG K + S TF GT Y+ PE Sbjct: 270 DVVYRDIKLENLMLDKDGHIKITDFGLCKEGI---------SDGATMKTFCGTPEYLAPE 320 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 VL D W LG +++M+ G PF + +F+ I+ ++RFP S EA+ L Sbjct: 321 VLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSL 380 Query: 542 IDKLLDVDP 568 + LL DP Sbjct: 381 LAGLLKKDP 389
>AKT3_MOUSE (Q9WUA6) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) Length = 479 Score = 134 bits (336), Expect = 2e-31 Identities = 74/191 (38%), Positives = 102/191 (53%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + L ++FQ L +E GGELF + R+ SED RFY AEIV L+YLHS Sbjct: 206 PFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSG 265 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +++RD+K ENL+L DGHIKI DFG K + + TF GT Y+ PE Sbjct: 266 KIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMK---------TFCGTPEYLAPE 316 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 VL D W LG +++M+ G PF + +F+ I+ D++FP S +A+ L Sbjct: 317 VLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSL 376 Query: 542 IDKLLDVDPTK 574 + LL DP K Sbjct: 377 LSGLLIKDPNK 387
>AKT3_HUMAN (Q9Y243) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) (STK-2) Length = 479 Score = 134 bits (336), Expect = 2e-31 Identities = 74/191 (38%), Positives = 102/191 (53%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + L ++FQ L +E GGELF + R+ SED RFY AEIV L+YLHS Sbjct: 206 PFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSG 265 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +++RD+K ENL+L DGHIKI DFG K + + TF GT Y+ PE Sbjct: 266 KIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMK---------TFCGTPEYLAPE 316 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 VL D W LG +++M+ G PF + +F+ I+ D++FP S +A+ L Sbjct: 317 VLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSL 376 Query: 542 IDKLLDVDPTK 574 + LL DP K Sbjct: 377 LSGLLIKDPNK 387
>CPK24_ARATH (Q9LDI3) CBL-interacting serine/threonine-protein kinase 24 (EC| 2.7.11.1) (SNF1-related kinase 3.11) (SALT OVERLY SENSITIVE 2 protein) Length = 446 Score = 134 bits (336), Expect = 2e-31 Identities = 75/191 (39%), Positives = 111/191 (58%), Gaps = 2/191 (1%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++RL+ +Y+ LE GGELFD+IV KGRL E E+R Y ++VD + + H Sbjct: 69 PNIVRLYEVLASPSKIYIVLEFVTGGELFDRIVHKGRLEESESRKYFQQLVDAVAHCHCK 128 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+ HRD+KPENLLL ++G++K++DFG + LP E T GT YV PE Sbjct: 129 GVYHRDLKPENLLLDTNGNLKVSDFG---------LSALPQEGVELLRTTCGTPNYVAPE 179 Query: 362 VLNSAPATFGN--DLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEAR 535 VL S G+ D+W+ G LF +L+G PF + ++++I A + P +FS E + Sbjct: 180 VL-SGQGYDGSAADIWSCGVILFVILAGYLPFSETDLPGLYRKINAAEFSCPPWFSAEVK 238 Query: 536 DLIDKLLDVDP 568 LI ++LD +P Sbjct: 239 FLIHRILDPNP 249
>KAD5_SCHPO (Q09831) Probable serine/threonine-protein kinase C4G8.05 (EC| 2.7.11.1) Length = 566 Score = 133 bits (335), Expect = 3e-31 Identities = 81/213 (38%), Positives = 118/213 (55%), Gaps = 25/213 (11%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRK-GR-LSEDEARFYAAEIVDILEYLH 175 P ++ L+ +FQ LY+ +E C GGE F + R+ GR LSE+EA+FY AE+ LEYLH Sbjct: 253 PFIVTLYHSFQSDEYLYLCMEYCMGGEFFRALQRRPGRCLSENEAKFYIAEVTAALEYLH 312 Query: 176 SVGLIHRDVKPENLLLTSDGHIKIADFGSVK-------PTV----DTPIKVLPNSTNERA 322 +G I+RD+KPEN+LL GHI ++DF K PTV + P + + ++ Sbjct: 313 LMGFIYRDLKPENILLHESGHIMLSDFDLSKQSNSAGAPTVIQARNAPSAQNAYALDTKS 372 Query: 323 C-------TFVGTAAYVPPEVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQ 481 C +FVGT Y+ PEV+ T D W LG ++ML ++PFK + + F Sbjct: 373 CIADFRTNSFVGTEEYIAPEVIKGCGHTSAVDWWTLGILFYEMLYATTPFKGKNRNMTFS 432 Query: 482 RIIARDLRFPEF-----FSDEARDLIDKLLDVD 565 I+ +D+ FPE+ S ++LI KLL D Sbjct: 433 NILHKDVIFPEYADAPSISSLCKNLIRKLLVKD 465
>AKT2_RAT (P47197) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 133 bits (335), Expect = 3e-31 Identities = 74/189 (39%), Positives = 100/189 (52%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + L + FQ L +E GG+LF + R+ +ED ARFY AEIV LEYLHS Sbjct: 210 PFLTALKYAFQTHDRLCFVMEYANGGDLFFHLSRERVFTEDRARFYGAEIVSALEYLHST 269 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +++RD+K ENL+L DGHIKI DFG K + S TF GT Y+ PE Sbjct: 270 DVVYRDIKLENLMLDKDGHIKITDFGLSKEGI---------SDGATMKTFCGTPEYLAPE 320 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 VL D W LG +++M+ G PF + +F+ I+ ++RFP EA+ L Sbjct: 321 VLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLGPEAKSL 380 Query: 542 IDKLLDVDP 568 + LL DP Sbjct: 381 LAGLLKKDP 389
>KS6B1_RAT (P67999) Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1)| (Ribosomal protein S6 kinase I) (S6K) (p70-S6K) Length = 525 Score = 133 bits (334), Expect = 4e-31 Identities = 71/185 (38%), Positives = 101/185 (54%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L + FQ LY+ LE GGELF Q+ R+G ED A FY AEI L +LH Sbjct: 153 PFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQK 212 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+KPEN++L GH+K+ DFG K ++ TF GT Y+ PE Sbjct: 213 GIIYRDLKPENIMLNHQGHVKLTDFGLCKESI---------HDGTVTHTFCGTIEYMAPE 263 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 +L + D W+LG ++ ML+G+ PF + +I+ L P + + EARDL Sbjct: 264 ILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDL 323 Query: 542 IDKLL 556 + KLL Sbjct: 324 LKKLL 328
>KS6B1_RABIT (P67998) Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1)| (Ribosomal protein S6 kinase I) (S6K) (p70-S6K) Length = 525 Score = 133 bits (334), Expect = 4e-31 Identities = 71/185 (38%), Positives = 101/185 (54%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L + FQ LY+ LE GGELF Q+ R+G ED A FY AEI L +LH Sbjct: 153 PFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQK 212 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+KPEN++L GH+K+ DFG K ++ TF GT Y+ PE Sbjct: 213 GIIYRDLKPENIMLNHQGHVKLTDFGLCKESI---------HDGTVTHTFCGTIEYMAPE 263 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 +L + D W+LG ++ ML+G+ PF + +I+ L P + + EARDL Sbjct: 264 ILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDL 323 Query: 542 IDKLL 556 + KLL Sbjct: 324 LKKLL 328
>KS6B1_MOUSE (Q8BSK8) Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1)| (Ribosomal protein S6 kinase I) (S6K) (p70-S6K) Length = 525 Score = 133 bits (334), Expect = 4e-31 Identities = 71/185 (38%), Positives = 101/185 (54%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L + FQ LY+ LE GGELF Q+ R+G ED A FY AEI L +LH Sbjct: 153 PFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQK 212 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+KPEN++L GH+K+ DFG K ++ TF GT Y+ PE Sbjct: 213 GIIYRDLKPENIMLNHQGHVKLTDFGLCKESI---------HDGTVTHTFCGTIEYMAPE 263 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 +L + D W+LG ++ ML+G+ PF + +I+ L P + + EARDL Sbjct: 264 ILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDL 323 Query: 542 IDKLL 556 + KLL Sbjct: 324 LKKLL 328
>KS6B1_HUMAN (P23443) Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1)| (Ribosomal protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) (p70-S6K) (p70-alpha) Length = 525 Score = 133 bits (334), Expect = 4e-31 Identities = 71/185 (38%), Positives = 101/185 (54%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L + FQ LY+ LE GGELF Q+ R+G ED A FY AEI L +LH Sbjct: 153 PFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQK 212 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+KPEN++L GH+K+ DFG K ++ TF GT Y+ PE Sbjct: 213 GIIYRDLKPENIMLNHQGHVKLTDFGLCKESI---------HDGTVTHTFCGTIEYMAPE 263 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 +L + D W+LG ++ ML+G+ PF + +I+ L P + + EARDL Sbjct: 264 ILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDL 323 Query: 542 IDKLL 556 + KLL Sbjct: 324 LKKLL 328
>SGK1_RAT (Q06226) Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 1) Length = 430 Score = 132 bits (333), Expect = 5e-31 Identities = 75/191 (39%), Positives = 105/191 (54%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L F+FQ + LY L+ GGELF + R+ E ARFYAAEI L YLHS+ Sbjct: 157 PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSL 216 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +++RD+KPEN+LL S GHI + DFG K ++ N TF GT Y+ PE Sbjct: 217 NIVYRDLKPENILLDSQGHIVLTDFGLCKENIE---------HNGTTSTFCGTPEYLAPE 267 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 VL+ P D W LG L++ML G PF + ++ I+ + L+ ++ AR L Sbjct: 268 VLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKN-ITNSARHL 326 Query: 542 IDKLLDVDPTK 574 ++ LL D TK Sbjct: 327 LEGLLQKDRTK 337
>PSK1_SCHPO (Q12706) Serine/threonine-protein kinase psk1 (EC 2.7.11.22)| Length = 436 Score = 132 bits (333), Expect = 5e-31 Identities = 71/189 (37%), Positives = 105/189 (55%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + RL++ FQD LY+ L+ GGELF + + L ED FY AE+ L +LH + Sbjct: 150 PFICRLYYAFQDHDRLYLILQYAPGGELFSHLAEQRMLPEDVVAFYTAELTLALIHLHKL 209 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+++RD+KPEN LL ++GHI + DFG KV N + R +FVGT Y PE Sbjct: 210 GIVYRDLKPENCLLDAEGHILLTDFGL--------SKVAENGADCR--SFVGTEEYCAPE 259 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 +L P D W++G +F +L+GS PF + I ++I P + + +ARD+ Sbjct: 260 ILLEQPYDHAVDWWSMGILIFDLLTGSPPFTANNHKRIMEKITRAKPNIPFYVTSDARDI 319 Query: 542 IDKLLDVDP 568 I+K L +P Sbjct: 320 INKFLKKNP 328
>PDPK1_CAEEL (Q9Y1J3) 3-phophoinositide-dependent protein kinase 1 (EC 2.7.11.1)| (Pdk-class protein kinase protein 1) Length = 636 Score = 132 bits (332), Expect = 7e-31 Identities = 74/219 (33%), Positives = 111/219 (50%), Gaps = 29/219 (13%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P V +L+ F D +Y + E G+L + + G ++F+A+EI+ L++LH Sbjct: 132 PFVTQLYTHFHDQARIYFVIGLVENGDLGESLCHFGSFDMLTSKFFASEILTGLQFLHDN 191 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVK-----------------------------PT 274 ++HRD+KP+N+L+ DGHI I DFGS + PT Sbjct: 192 KIVHRDMKPDNVLIQKDGHILITDFGSAQAFGGLQLSQEGFTDANQASSRSSDSGSPPPT 251 Query: 275 VDTPIKVLPNSTNERACTFVGTAAYVPPEVLNSAPATFGNDLWALGCTLFQMLSGSSPFK 454 + +P R TFVGTA YV PE+L D+W LGC LFQ L+G PF+ Sbjct: 252 RFYSDEEVPEENTARRTTFVGTALYVSPEMLADGDVGPQTDIWGLGCILFQCLAGQPPFR 311 Query: 455 DASEWLIFQRIIARDLRFPEFFSDEARDLIDKLLDVDPT 571 +++ + +RI D FPE F +EA ++I K+L DP+ Sbjct: 312 AVNQYHLLKRIQELDFSFPEGFPEEASEIIAKILVRDPS 350
>KN8R_YEAST (P53739) Probable serine/threonine-protein kinase YNR047W (EC| 2.7.11.1) Length = 893 Score = 131 bits (330), Expect = 1e-30 Identities = 77/207 (37%), Positives = 112/207 (54%), Gaps = 16/207 (7%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQI-VRKGR-LSEDEARFYAAEIVDILEYLH 175 P ++ L+ +FQ LY+ +E C GGE F + RK + + ED+ARFYA+E+ LEYLH Sbjct: 554 PFIVTLYHSFQSEDYLYLCMEYCMGGEFFRALQTRKTKCICEDDARFYASEVTAALEYLH 613 Query: 176 SVGLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNE------------R 319 +G I+RD+KPEN+LL GHI ++DF D+ + V+ S R Sbjct: 614 LLGFIYRDLKPENILLHQSGHIMLSDFDLSIQAKDSKVPVVKGSAQSTLVDTKICSDGFR 673 Query: 320 ACTFVGTAAYVPPEVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARD 499 +FVGT Y+ PEV+ T D W LG +++ML G +PFK + F I+ + Sbjct: 674 TNSFVGTEEYIAPEVIRGNGHTAAVDWWTLGILIYEMLFGFTPFKGDNTNETFTNILKNE 733 Query: 500 LRFP--EFFSDEARDLIDKLLDVDPTK 574 + FP S +DLI KLL + +K Sbjct: 734 VSFPNNNEISRTCKDLIKKLLTKNESK 760
>AKT1_RAT (P47196) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) Length = 480 Score = 131 bits (329), Expect = 2e-30 Identities = 75/192 (39%), Positives = 103/192 (53%), Gaps = 1/192 (0%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + L ++FQ L +E GGELF + R+ SED ARFY AEIV L+YLHS Sbjct: 208 PFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSE 267 Query: 182 -GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPP 358 +++RD+K ENL+L DGHIKI DFG K + + TF GT Y+ P Sbjct: 268 KNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMK---------TFCGTPEYLAP 318 Query: 359 EVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARD 538 EVL D W LG +++M+ G PF + +F+ I+ ++RFP EA+ Sbjct: 319 EVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKS 378 Query: 539 LIDKLLDVDPTK 574 L+ LL DPT+ Sbjct: 379 LLSGLLKKDPTQ 390
>IPL1_DEBHA (Q6BVA0) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 412 Score = 131 bits (329), Expect = 2e-30 Identities = 71/191 (37%), Positives = 111/191 (58%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + RL+ F D ++Y+ LE GEL+ + + R ++ A Y ++ L+YLH+ Sbjct: 206 PKISRLYGFFYDHKNVYLILEYSIHGELYHHLKVQRRFNDATASHYIYQVALALDYLHTK 265 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +IHRD+KPEN+LL++D IK++DFG +K LP+S+ +R T GT Y+PPE Sbjct: 266 HIIHRDIKPENILLSTDNCIKLSDFG-------WSVKSLPSSSTKR-LTICGTLDYLPPE 317 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ S + D+W+LG ++ L G PF++ + ++RI DL+ P F S EA DL Sbjct: 318 MIESNEHDYTVDIWSLGILCYEFLVGKPPFEEIDKNSTYKRIAKVDLKIPSFLSSEATDL 377 Query: 542 IDKLLDVDPTK 574 I +LL P K Sbjct: 378 ILRLLQKSPKK 388
>AKT_MLVAT (P31748) AKT kinase transforming protein (EC 2.7.11.1)| Length = 501 Score = 131 bits (329), Expect = 2e-30 Identities = 75/192 (39%), Positives = 103/192 (53%), Gaps = 1/192 (0%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + L ++FQ L +E GGELF + R+ SED ARFY AEIV L+YLHS Sbjct: 229 PFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSE 288 Query: 182 -GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPP 358 +++RD+K ENL+L DGHIKI DFG K + + TF GT Y+ P Sbjct: 289 KNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMK---------TFCGTPEYLAP 339 Query: 359 EVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARD 538 EVL D W LG +++M+ G PF + +F+ I+ ++RFP EA+ Sbjct: 340 EVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKS 399 Query: 539 LIDKLLDVDPTK 574 L+ LL DPT+ Sbjct: 400 LLSGLLKKDPTQ 411
>AKT1_BOVIN (Q01314) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) Length = 480 Score = 130 bits (328), Expect = 2e-30 Identities = 75/190 (39%), Positives = 102/190 (53%), Gaps = 1/190 (0%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + L ++FQ L +E GGELF + R+ SED ARFY AEIV L+YLHS Sbjct: 208 PSLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSE 267 Query: 182 G-LIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPP 358 +++RD+K ENL+L DGHIKI DFG K + + TF GT Y+ P Sbjct: 268 KEVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMK---------TFCGTPEYLAP 318 Query: 359 EVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARD 538 EVL D W LG +++M+ G PF + +F+ I+ ++RFP S EA+ Sbjct: 319 EVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLSPEAKS 378 Query: 539 LIDKLLDVDP 568 L+ LL DP Sbjct: 379 LLSGLLKKDP 388
>KS6A6_HUMAN (Q9UK32) Ribosomal protein S6 kinase alpha-6 (EC 2.7.11.1)| (S6K-alpha 6) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4) Length = 745 Score = 130 bits (328), Expect = 2e-30 Identities = 65/189 (34%), Positives = 109/189 (57%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +++L + FQ LY+ L+ GG++F ++ ++ +E++ +FY AE+ L++LH + Sbjct: 133 PFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLHQL 192 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+++RD+KPEN+LL GHIK+ DFG K +VD ++A +F GT Y+ PE Sbjct: 193 GIVYRDLKPENILLDEIGHIKLTDFGLSKESVD---------QEKKAYSFCGTVEYMAPE 243 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 V+N + D W+ G +F+ML+G+ PF+ I+ L P+F S EA+ L Sbjct: 244 VVNRRGHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSAEAQSL 303 Query: 542 IDKLLDVDP 568 + L +P Sbjct: 304 LRMLFKRNP 312 Score = 87.4 bits (215), Expect = 3e-17 Identities = 64/203 (31%), Positives = 96/203 (47%), Gaps = 14/203 (6%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +I L F D +Y+ + +GGEL D+I+++ SE EA I ++YLH Sbjct: 478 PNIITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHCQ 537 Query: 182 GLIHRDVKPENLLL----TSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAY 349 G++HRD+KP N+L S I+I DFG K N T TA + Sbjct: 538 GVVHRDLKPSNILYMDESASADSIRICDFGFAKQL---------RGENGLLLTPCYTANF 588 Query: 350 VPPEVLNSAPATFGNDLWALGCTLFQMLSGSSPF----KDASEWLIFQRIIARDLRFP-- 511 V PEVL D+W+LG + ML+G +PF D E ++ + + +F Sbjct: 589 VAPEVLMQQGYDAACDIWSLGVLFYTMLAGYTPFANGPNDTPEEILLR---IGNGKFSLS 645 Query: 512 ----EFFSDEARDLIDKLLDVDP 568 + SD A+DL+ +L +DP Sbjct: 646 GGNWDNISDGAKDLLSHMLHMDP 668
>KGP2_RAT (Q64595) cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2)| (cGKII) (Type II cGMP-dependent protein kinase) Length = 762 Score = 130 bits (327), Expect = 3e-30 Identities = 65/193 (33%), Positives = 111/193 (57%), Gaps = 2/193 (1%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +++L+ TF+D+ +YM LE+C GGEL+ + +G E ++F A + + +YLH + Sbjct: 511 PFIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYLHRL 570 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+KPENL+L +DG++K+ DFG K + ++ TF GT YV PE Sbjct: 571 GIIYRDLKPENLILDADGYLKLVDFGFAKKI----------GSGQKTWTFCGTPEYVAPE 620 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRII--ARDLRFPEFFSDEAR 535 V+ + F D W+LG ++++L+G+ PF + + + I+ + FP + Sbjct: 621 VILNKGHDFSVDFWSLGILVYELLTGNPPFSGIDQMMTYNLILKGIEKMDFPRKITRRPE 680 Query: 536 DLIDKLLDVDPTK 574 DLI +L +PT+ Sbjct: 681 DLIRRLCRQNPTE 693
>STK6_XENLA (Q91820) Serine/threonine-protein kinase Eg2 (EC 2.7.11.1) (pEg2)| (p46Eg265) Length = 407 Score = 130 bits (326), Expect = 3e-30 Identities = 69/189 (36%), Positives = 107/189 (56%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++RL+ F D+ +Y+ L+ GGELF ++ + R + + Y ++ + L Y HS Sbjct: 198 PNILRLYGYFHDASRVYLILDYAPGGELFRELQKCTRFDDQRSAMYIKQLAEALLYCHSK 257 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +IHRD+KPENLLL S+G +KIADFG +V P + R T GT Y+PPE Sbjct: 258 KVIHRDIKPENLLLGSNGELKIADFGW---SVHAP--------SSRRTTLCGTLDYLPPE 306 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ DLW+LG ++ L G PF+ + ++RI + ++P + S+EARDL Sbjct: 307 MIEGRMHDETVDLWSLGVLCYEFLVGKPPFETDTHQETYRRISKVEFQYPPYVSEEARDL 366 Query: 542 IDKLLDVDP 568 + KLL +P Sbjct: 367 VSKLLKHNP 375
>KGP2_MOUSE (Q61410) cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2)| (cGKII) (Type II cGMP-dependent protein kinase) Length = 762 Score = 130 bits (326), Expect = 3e-30 Identities = 65/193 (33%), Positives = 111/193 (57%), Gaps = 2/193 (1%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +++L+ TF+D+ +YM LE+C GGEL+ + +G E ++F A + + +YLH + Sbjct: 511 PFIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYLHLL 570 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+KPENL+L +DG++K+ DFG K + ++ TF GT YV PE Sbjct: 571 GIIYRDLKPENLILDADGYLKLVDFGFAKKI----------GSGQKTWTFCGTPEYVAPE 620 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRII--ARDLRFPEFFSDEAR 535 V+ + F D W+LG ++++L+G+ PF + + + I+ + FP + Sbjct: 621 VILNKGHDFSVDFWSLGILVYELLTGNPPFSGIDQMMTYNLILKGIEKMDFPRKITRRPE 680 Query: 536 DLIDKLLDVDPTK 574 DLI +L +PT+ Sbjct: 681 DLIRRLCRQNPTE 693
>SGK2_HUMAN (Q9HBY8) Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 2) Length = 427 Score = 130 bits (326), Expect = 3e-30 Identities = 73/188 (38%), Positives = 101/188 (53%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L ++FQ LY L+ GGELF + R+ R E ARFYAAE+ + YLHS+ Sbjct: 154 PFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSL 213 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +I+RD+KPEN+LL GH+ + DFG K V+ P T TF GT Y+ PE Sbjct: 214 NIIYRDLKPENILLDCQGHVVLTDFGLCKEGVE------PEDTTS---TFCGTPEYLAPE 264 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 VL P D W LG L++ML G PF +++ I+ + L+ P + A DL Sbjct: 265 VLRKEPYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDL 324 Query: 542 IDKLLDVD 565 + LL D Sbjct: 325 LQSLLHKD 332
>ARK1_SCHPO (O59790) Serine/threonine-protein kinase ark1 (EC 2.7.11.1)| (Aurora-related kinase 1) Length = 355 Score = 130 bits (326), Expect = 3e-30 Identities = 74/190 (38%), Positives = 106/190 (55%), Gaps = 1/190 (0%) Frame = +2 Query: 8 VIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSVGL 187 ++RL+ F D +Y+ LE GEL+ + R R SE+ A Y ++ + L YLH + Sbjct: 149 ILRLYGHFHDEKRIYLILEFAGRGELYQHLRRAKRFSEEVASKYIFQMANALSYLHKKHV 208 Query: 188 IHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPEVL 367 IHRD+KPEN+LL DG IK++DFG +V P + R T GT Y+PPE++ Sbjct: 209 IHRDIKPENILLGIDGEIKLSDFGW---SVHAP--------SNRRTTLCGTLDYLPPEMV 257 Query: 368 NSAPATFGNDLWALGCTLFQMLSGSSPFKDAS-EWLIFQRIIARDLRFPEFFSDEARDLI 544 T DLW+LG ++ L G+ PF+D S ++RI DL+ P F +ARDLI Sbjct: 258 EGKEHTEKVDLWSLGVLTYEFLVGAPPFEDMSGHSATYKRIAKVDLKIPSFVPPDARDLI 317 Query: 545 DKLLDVDPTK 574 +LL +P K Sbjct: 318 SRLLQHNPEK 327
>KGP2_HUMAN (Q13237) cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2)| (cGKII) (Type II cGMP-dependent protein kinase) Length = 762 Score = 129 bits (324), Expect = 6e-30 Identities = 64/193 (33%), Positives = 111/193 (57%), Gaps = 2/193 (1%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +++L+ TF+D+ +YM LE+C GGEL+ + +G E ++F A + + +YLH + Sbjct: 511 PFIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYLHRL 570 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+KPENL+L ++G++K+ DFG K + ++ TF GT YV PE Sbjct: 571 GIIYRDLKPENLILDAEGYLKLVDFGFAKKI----------GSGQKTWTFCGTPEYVAPE 620 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRII--ARDLRFPEFFSDEAR 535 V+ + F D W+LG ++++L+G+ PF + + + I+ + FP + Sbjct: 621 VILNKGHDFSVDFWSLGILVYELLTGNPPFSGVDQMMTYNLILKGIEKMDFPRKITRRPE 680 Query: 536 DLIDKLLDVDPTK 574 DLI +L +PT+ Sbjct: 681 DLIRRLCRQNPTE 693
>KGP24_DROME (Q03043) cGMP-dependent protein kinase, isozyme 2 forms| cD4/T1/T3A/T3B (EC 2.7.11.12) (CGK) (Foraging protein) Length = 1088 Score = 129 bits (324), Expect = 6e-30 Identities = 70/191 (36%), Positives = 104/191 (54%), Gaps = 2/191 (1%) Frame = +2 Query: 8 VIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSVGL 187 +++LF TF+D LYM +ESC GGEL+ + KG + RFY A +V+ +YLHS + Sbjct: 838 IVKLFKTFKDKKYLYMLMESCLGGELWTILRDKGNFDDSTTRFYTACVVEAFDYLHSRNI 897 Query: 188 IHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPEVL 367 I+RD+KPENLLL G++K+ DFG K T + TF GT YV PEV+ Sbjct: 898 IYRDLKPENLLLNERGYVKLVDFGFAKKL----------QTGRKTWTFCGTPEYVAPEVI 947 Query: 368 NSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRII--ARDLRFPEFFSDEARDL 541 + D W+LG +F++L+G+ PF + + I+ + FP + A +L Sbjct: 948 LNRGHDISADYWSLGVLMFELLTGTPPFTGSDPMRTYNIILKGIDAIEFPRNITRNASNL 1007 Query: 542 IDKLLDVDPTK 574 I KL +P + Sbjct: 1008 IKKLCRDNPAE 1018
>KGP25_DROME (P32023) cGMP-dependent protein kinase, isozyme 2 forms cD5/T2 (EC| 2.7.11.12) (CGK) (Foraging protein) Length = 934 Score = 129 bits (324), Expect = 6e-30 Identities = 70/191 (36%), Positives = 104/191 (54%), Gaps = 2/191 (1%) Frame = +2 Query: 8 VIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSVGL 187 +++LF TF+D LYM +ESC GGEL+ + KG + RFY A +V+ +YLHS + Sbjct: 684 IVKLFKTFKDKKYLYMLMESCLGGELWTILRDKGNFDDSTTRFYTACVVEAFDYLHSRNI 743 Query: 188 IHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPEVL 367 I+RD+KPENLLL G++K+ DFG K T + TF GT YV PEV+ Sbjct: 744 IYRDLKPENLLLNERGYVKLVDFGFAKKL----------QTGRKTWTFCGTPEYVAPEVI 793 Query: 368 NSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRII--ARDLRFPEFFSDEARDL 541 + D W+LG +F++L+G+ PF + + I+ + FP + A +L Sbjct: 794 LNRGHDISADYWSLGVLMFELLTGTPPFTGSDPMRTYNIILKGIDAIEFPRNITRNASNL 853 Query: 542 IDKLLDVDPTK 574 I KL +P + Sbjct: 854 IKKLCRDNPAE 864
>GAD8_SCHPO (Q9P7J8) Serine/threonine-protein kinase gad8 (EC 2.7.11.1)| Length = 569 Score = 129 bits (324), Expect = 6e-30 Identities = 73/191 (38%), Positives = 106/191 (55%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L F+FQ LY+ L GGELF + R+G A+FY AE++ LE LH Sbjct: 288 PFIVPLKFSFQSPGKLYLVLAFVNGGELFHHLQREGCFDTYRAKFYIAELLVALECLHEF 347 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +I+RD+KPEN+LL GHI + DFG K L + +R TF GT Y+ PE Sbjct: 348 NVIYRDLKPENILLDYTGHIALCDFGLCK---------LNMAKTDRTNTFCGTPEYLAPE 398 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 +L T D W LG L++M++G PF D + ++++I+ LRFP+ ++A+DL Sbjct: 399 LLLGHGYTKVVDWWTLGVLLYEMITGLPPFYDENINEMYRKILQDPLRFPDNIDEKAKDL 458 Query: 542 IDKLLDVDPTK 574 + LL P K Sbjct: 459 LSGLLTRAPEK 469
>AKT1_MOUSE (P31750) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (AKT1 kinase) (Protein kinase B) (PKB) (C-AKT) (Thymoma viral proto-oncogene) Length = 480 Score = 129 bits (323), Expect = 8e-30 Identities = 74/192 (38%), Positives = 102/192 (53%), Gaps = 1/192 (0%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + L ++FQ L +E GGELF + R+ SED ARFY AEIV L+YLHS Sbjct: 208 PFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSE 267 Query: 182 -GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPP 358 +++RD+K ENL+L DGHIKI DFG K + + TF GT Y+ P Sbjct: 268 KNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMK---------TFCGTPEYLAP 318 Query: 359 EVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARD 538 EVL D W LG +++M+ G PF + +F+ I+ ++ FP EA+ Sbjct: 319 EVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIAFPRTLGPEAKS 378 Query: 539 LIDKLLDVDPTK 574 L+ LL DPT+ Sbjct: 379 LLSGLLKKDPTQ 390
>AKT1_HUMAN (P31749) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) (C-AKT) Length = 480 Score = 129 bits (323), Expect = 8e-30 Identities = 74/190 (38%), Positives = 101/190 (53%), Gaps = 1/190 (0%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + L ++FQ L +E GGELF + R+ SED ARFY AEIV L+YLHS Sbjct: 208 PFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSE 267 Query: 182 -GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPP 358 +++RD+K ENL+L DGHIKI DFG K + + TF GT Y+ P Sbjct: 268 KNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMK---------TFCGTPEYLAP 318 Query: 359 EVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARD 538 EVL D W LG +++M+ G PF + +F+ I+ ++RFP EA+ Sbjct: 319 EVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKS 378 Query: 539 LIDKLLDVDP 568 L+ LL DP Sbjct: 379 LLSGLLKKDP 388
>KPCZ_RAT (P09217) Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)| Length = 592 Score = 129 bits (323), Expect = 8e-30 Identities = 73/196 (37%), Positives = 109/196 (55%), Gaps = 7/196 (3%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L FQ + L++ +E GG+L + R+ +L E+ ARFYAAEI L +LH Sbjct: 311 PFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLHER 370 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+K +N+LL +DGHIK+ D+G K + P T TF GT Y+ PE Sbjct: 371 GIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLG------PGDTTS---TFCGTPNYIAPE 421 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDA-------SEWLIFQRIIARDLRFPEFF 520 +L F D WALG +F+M++G SPF +E +FQ I+ + +R P F Sbjct: 422 ILRGEEYGFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFL 481 Query: 521 SDEARDLIDKLLDVDP 568 S +A ++ L+ DP Sbjct: 482 SVKASHVLKGFLNKDP 497
>KPCZ_MOUSE (Q02956) Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)| Length = 592 Score = 129 bits (323), Expect = 8e-30 Identities = 73/196 (37%), Positives = 109/196 (55%), Gaps = 7/196 (3%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L FQ + L++ +E GG+L + R+ +L E+ ARFYAAEI L +LH Sbjct: 311 PFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLHER 370 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+K +N+LL +DGHIK+ D+G K + P T TF GT Y+ PE Sbjct: 371 GIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLG------PGDTTS---TFCGTPNYIAPE 421 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDA-------SEWLIFQRIIARDLRFPEFF 520 +L F D WALG +F+M++G SPF +E +FQ I+ + +R P F Sbjct: 422 ILRGEEYGFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFL 481 Query: 521 SDEARDLIDKLLDVDP 568 S +A ++ L+ DP Sbjct: 482 SVKASHVLKGFLNKDP 497
>KPCZ_HUMAN (Q05513) Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)| Length = 592 Score = 129 bits (323), Expect = 8e-30 Identities = 73/196 (37%), Positives = 109/196 (55%), Gaps = 7/196 (3%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L FQ + L++ +E GG+L + R+ +L E+ ARFYAAEI L +LH Sbjct: 311 PFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLHER 370 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+K +N+LL +DGHIK+ D+G K + P T TF GT Y+ PE Sbjct: 371 GIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLG------PGDTTS---TFCGTPNYIAPE 421 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDA-------SEWLIFQRIIARDLRFPEFF 520 +L F D WALG +F+M++G SPF +E +FQ I+ + +R P F Sbjct: 422 ILRGEEYGFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFL 481 Query: 521 SDEARDLIDKLLDVDP 568 S +A ++ L+ DP Sbjct: 482 SVKASHVLKGFLNKDP 497
>KPC4_DROME (P83099) Putative protein kinase C, delta type homolog (EC| 2.7.11.13) Length = 643 Score = 129 bits (323), Expect = 8e-30 Identities = 73/191 (38%), Positives = 103/191 (53%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + LF TFQ L+ +E GG+L I GR SE+ ARFY AEI+ L++LH Sbjct: 374 PYLCHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGRFSEERARFYGAEIISGLKFLHKK 433 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+K +N+LL +GH++IADFG K L ++ A +F GT Y+ PE Sbjct: 434 GIIYRDLKLDNVLLDYEGHVRIADFGMCK---------LQIYLDKTADSFCGTPDYMAPE 484 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ D W+ G L++ML G SPF E +F I FP + S EA + Sbjct: 485 IIKGEKYNQNVDWWSFGVLLYEMLIGQSPFSGCDEDELFWSICNEIPWFPVYISAEATGI 544 Query: 542 IDKLLDVDPTK 574 + LL+ D TK Sbjct: 545 LKGLLEKDYTK 555
>SGK2_RAT (Q8R4U9) Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 2) (Fragment) Length = 302 Score = 129 bits (323), Expect = 8e-30 Identities = 71/188 (37%), Positives = 100/188 (53%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L ++FQ LY L+ GGELF + R+ R E ARFY AE+ + YLHS+ Sbjct: 77 PFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQREHRFLEPRARFYTAEVASAIGYLHSL 136 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +I+RD+KPEN+LL GH+ + DFG K V+ E TF GT Y+ PE Sbjct: 137 NIIYRDLKPENILLDCQGHVVLTDFGLCKECVE---------PEETTSTFCGTPEYLAPE 187 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 VL P D W LG L++ML G PF + +++ I+ + L+ P + A DL Sbjct: 188 VLRKEPYDRAVDWWCLGAVLYEMLHGLPPFFNTDVAQMYENILHQPLQIPGGRTVAACDL 247 Query: 542 IDKLLDVD 565 + LL D Sbjct: 248 LQGLLHKD 255
>KPCZ_RABIT (O19111) Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)| Length = 591 Score = 129 bits (323), Expect = 8e-30 Identities = 73/196 (37%), Positives = 109/196 (55%), Gaps = 7/196 (3%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L FQ + L++ +E GG+L + R+ +L E+ ARFYAAEI L +LH Sbjct: 310 PFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLHER 369 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+K +N+LL +DGHIK+ D+G K + P T TF GT Y+ PE Sbjct: 370 GIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLG------PGDTTS---TFCGTPNYIAPE 420 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDA-------SEWLIFQRIIARDLRFPEFF 520 +L F D WALG +F+M++G SPF +E +FQ I+ + +R P F Sbjct: 421 ILRGEEYGFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFL 480 Query: 521 SDEARDLIDKLLDVDP 568 S +A ++ L+ DP Sbjct: 481 SVKASHVLKGFLNKDP 496
>SGK2_MOUSE (Q9QZS5) Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 2) Length = 367 Score = 129 bits (323), Expect = 8e-30 Identities = 71/188 (37%), Positives = 100/188 (53%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L ++FQ LY L+ GGELF + R+ R E ARFY AE+ + YLHS+ Sbjct: 94 PFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYTAEVASAIGYLHSL 153 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +I+RD+KPEN+LL GH+ + DFG K V+ E TF GT Y+ PE Sbjct: 154 NIIYRDLKPENILLDCQGHVVLTDFGLCKECVE---------PEETTSTFCGTPEYLAPE 204 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 VL P D W LG L++ML G PF + +++ I+ + L+ P + A DL Sbjct: 205 VLRKEPYDRAVDWWCLGAVLYEMLHGLPPFFNTDVAQMYENILHQPLQIPGGRTVAACDL 264 Query: 542 IDKLLDVD 565 + LL D Sbjct: 265 LQGLLHKD 272
>STK6L_XENLA (Q91819) Serine/threonine-protein kinase Eg2-like (EC 2.7.11.1)| (p46XlEg22) Length = 408 Score = 129 bits (323), Expect = 8e-30 Identities = 68/189 (35%), Positives = 107/189 (56%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++RL+ F D+ +Y+ L+ GGELF ++ + R + + Y ++ + L Y HS Sbjct: 198 PNILRLYGYFHDASRVYLILDYAPGGELFRELQKCTRFDDQRSALYIKQLAEALLYCHSK 257 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +IHRD+KPENLLL S+G +KIADFG +V P + R T GT Y+PPE Sbjct: 258 KVIHRDIKPENLLLGSNGELKIADFGW---SVHAP--------SSRRTTLCGTLDYLPPE 306 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ DLW+LG ++ L G PF+ + ++RI + ++P + S+EA+DL Sbjct: 307 MIEGRMHDEKVDLWSLGVLCYEFLVGKPPFETDTHQETYRRISKVEFQYPPYVSEEAKDL 366 Query: 542 IDKLLDVDP 568 + KLL +P Sbjct: 367 VSKLLKHNP 375
>KS6A5_CHICK (Q5F3L1) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1)| Length = 789 Score = 128 bits (322), Expect = 1e-29 Identities = 70/197 (35%), Positives = 114/197 (57%), Gaps = 6/197 (3%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L + FQ L++ L+ GGELF + ++ R SE+E + Y EIV LE+LH + Sbjct: 102 PFLVTLHYAFQTDTKLHLILDYINGGELFTHLSQRERFSENEVQIYIGEIVLALEHLHKL 161 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+K EN+LL SDGH+ + DFG K + NERA +F GT Y+ P+ Sbjct: 162 GIIYRDIKLENILLDSDGHVVLTDFGLSKEFL--------TDENERAYSFCGTIEYMAPD 213 Query: 362 VLNSAPATFGN--DLWALGCTLFQMLSGSSPF----KDASEWLIFQRIIARDLRFPEFFS 523 ++ D W++G ++++L+G+SPF + S+ I +RI+ + +P+ S Sbjct: 214 IVRGGDTGHDKAVDWWSVGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMS 273 Query: 524 DEARDLIDKLLDVDPTK 574 ++D+I +LL DP K Sbjct: 274 ALSKDIIQRLLMKDPKK 290 Score = 110 bits (275), Expect = 3e-24 Identities = 72/207 (34%), Positives = 105/207 (50%), Gaps = 16/207 (7%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P V++L + D ++ +E +GGEL ++I +K SE EA +V + ++H V Sbjct: 469 PNVVKLHEVYHDQLHTFLVMELLKGGELLERIQKKQHFSETEASHIMRRLVSAVSHMHDV 528 Query: 182 GLIHRDVKPENLLLTSD---GHIKIADFG--SVKPTVDTPIKVLPNSTNERACTFVGTAA 346 G++HRD+KPENLL T + IKI DFG +KP + P+K T T Sbjct: 529 GVVHRDLKPENLLFTDETDNSEIKIIDFGFARLKPPDNQPLK-----------TPCFTLH 577 Query: 347 YVPPEVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWL-------IFQRIIARDLR 505 Y PE+ N DLW+LG L+ MLSG PF+ + L I ++I + Sbjct: 578 YAAPELFNHNGYDESCDLWSLGVILYTMLSGQVPFQSQDKSLTCTSALEIMKKIKKGEFS 637 Query: 506 FP----EFFSDEARDLIDKLLDVDPTK 574 F + S+EA++LI LL VDP K Sbjct: 638 FEGEAWKNVSEEAKELIQGLLTVDPNK 664
>AKT1_XENLA (Q98TY9) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase Akt-1) (Protein kinase B, alpha) (PKB alpha) (xAkt) Length = 481 Score = 128 bits (321), Expect = 1e-29 Identities = 74/190 (38%), Positives = 101/190 (53%), Gaps = 1/190 (0%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + L ++FQ L +E GGELF + R+ SED ARFY AEIV L+YLHS Sbjct: 209 PFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERIFSEDRARFYGAEIVSALDYLHSE 268 Query: 182 -GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPP 358 +++RD+K ENL+L DGHIKI DFG K + + TF GT Y+ P Sbjct: 269 KNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMK---------TFCGTPEYLAP 319 Query: 359 EVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARD 538 EVL D W LG +++M+ G PF + +F+ I+ ++RFP EA+ Sbjct: 320 EVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLLPEAKS 379 Query: 539 LIDKLLDVDP 568 L+ LL DP Sbjct: 380 LLSGLLKKDP 389
>KKK1_YEAST (P34244) Probable serine/threonine-protein kinase YKL101W (EC| 2.7.11.1) Length = 1518 Score = 128 bits (321), Expect = 1e-29 Identities = 76/191 (39%), Positives = 109/191 (57%), Gaps = 2/191 (1%) Frame = +2 Query: 8 VIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSVGL 187 V+ LF +++ LY+ LE +GGELFD +V KG+L E EA Y +IV+ + Y HS + Sbjct: 176 VMALFEVWENKSELYLVLEYVDGGELFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNI 235 Query: 188 IHRDVKPENLLL-TSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPEV 364 HRD+KPENLLL + IKIADFG ++ P K+L S G+ Y PE+ Sbjct: 236 CHRDLKPENLLLDKKNRRIKIADFGMA--ALELPNKLLKTS--------CGSPHYASPEI 285 Query: 365 LNSAPATFG-NDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 + P G +D+W+ G LF +L+G PF D + + ++ + + P S EARDL Sbjct: 286 VMGRPYHGGPSDVWSCGIVLFALLTGHLPFNDDNIKKLLLKVQSGKYQMPSNLSSEARDL 345 Query: 542 IDKLLDVDPTK 574 I K+L +DP K Sbjct: 346 ISKILVIDPEK 356
>KIN11_ARATH (P92958) SNF1-related protein kinase catalytic alpha subunit KIN11| (EC 2.7.11.1) (AKIN11) (AKIN alpha1) Length = 512 Score = 127 bits (318), Expect = 3e-29 Identities = 76/192 (39%), Positives = 105/192 (54%), Gaps = 1/192 (0%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +IR + + + +Y+ +E + GELFD IV KGRL EDEAR + +I+ +EY H Sbjct: 78 PHIIRQYEVIETTSDIYVVMEYVKSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHRN 137 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTP-IKVLPNSTNERACTFVGTAAYVPP 358 ++HRD+KPENLLL S +IKIADFG D +K S N A + Y P Sbjct: 138 MVVHRDLKPENLLLDSRCNIKIADFGLSNVMRDGHFLKTSCGSPNYAAPEVISGKLYAGP 197 Query: 359 EVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARD 538 EV D+W+ G L+ +L G+ PF D + +F++I P S EARD Sbjct: 198 EV----------DVWSCGVILYALLCGTLPFDDENIPNLFKKIKGGIYTLPSHLSSEARD 247 Query: 539 LIDKLLDVDPTK 574 LI ++L VDP K Sbjct: 248 LIPRMLIVDPVK 259
>KPC3_CAEEL (Q19266) Protein kinase C-like 3 (EC 2.7.11.13) (Atypical protein| kinase C-3) (aPKC3) Length = 597 Score = 126 bits (317), Expect = 4e-29 Identities = 68/199 (34%), Positives = 109/199 (54%), Gaps = 8/199 (4%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L FQ L+ +E GG+L + ++ +L E+ ARFY+ EI+ L +LHS Sbjct: 312 PFLVGLHSCFQTESRLFFVIEFVPGGDLMFHMQQQRKLPEEHARFYSGEIILALHFLHSR 371 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+K +N+L+ ++GHIK+ D+G K + + TF GT Y+ PE Sbjct: 372 GIIYRDLKLDNVLIDAEGHIKLTDYGMCKENI---------KDGDLTSTFCGTPNYIAPE 422 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPF--------KDASEWLIFQRIIARDLRFPEF 517 +L F D WALG +F+M++G SPF ++ +E +FQ I+ R +R P Sbjct: 423 ILRGDEYGFSVDWWALGVLMFEMMAGRSPFDIVGMQNSEENTEDYLFQIILERQIRIPRS 482 Query: 518 FSDEARDLIDKLLDVDPTK 574 S A ++ L+ DPT+ Sbjct: 483 LSVRASGILKGFLNKDPTE 501
>KS6A5_HUMAN (O75582) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RSKL) Length = 802 Score = 126 bits (317), Expect = 4e-29 Identities = 71/197 (36%), Positives = 113/197 (57%), Gaps = 6/197 (3%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L + FQ L++ L+ GGELF + ++ R +E E + Y EIV LE+LH + Sbjct: 112 PFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHLHKL 171 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+K EN+LL S+GH+ + DFG K V ERA +F GT Y+ P+ Sbjct: 172 GIIYRDIKLENILLDSNGHVVLTDFGLSKEFV--------ADETERAYSFCGTIEYMAPD 223 Query: 362 VLNSAPATFGN--DLWALGCTLFQMLSGSSPF----KDASEWLIFQRIIARDLRFPEFFS 523 ++ + D W+LG ++++L+G+SPF + S+ I +RI+ + +P+ S Sbjct: 224 IVRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMS 283 Query: 524 DEARDLIDKLLDVDPTK 574 A+DLI +LL DP K Sbjct: 284 ALAKDLIQRLLMKDPKK 300 Score = 118 bits (296), Expect = 1e-26 Identities = 76/207 (36%), Positives = 106/207 (51%), Gaps = 16/207 (7%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +++L F D ++ +E GGELF++I +K SE EA + ++V + ++H V Sbjct: 479 PNIVKLHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDV 538 Query: 182 GLIHRDVKPENLLLTSDG---HIKIADFG--SVKPTVDTPIKVLPNSTNERACTFVGTAA 346 G++HRD+KPENLL T + IKI DFG +KP + P+K T T Sbjct: 539 GVVHRDLKPENLLFTDENDNLEIKIIDFGFARLKPPDNQPLK-----------TPCFTLH 587 Query: 347 YVPPEVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWL-------IFQRIIARDLR 505 Y PE+LN DLW+LG L+ MLSG PF+ L I ++I D Sbjct: 588 YAAPELLNQNGYDESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFS 647 Query: 506 FP----EFFSDEARDLIDKLLDVDPTK 574 F + S EA+DLI LL VDP K Sbjct: 648 FEGEAWKNVSQEAKDLIQGLLTVDPNK 674
>IPL1_YARLI (Q6C3J2) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 371 Score = 126 bits (317), Expect = 4e-29 Identities = 71/190 (37%), Positives = 107/190 (56%), Gaps = 1/190 (0%) Frame = +2 Query: 8 VIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSVGL 187 V+RLF F D +Y+ LE GEL+ + + R +E A Y ++ + L YLH + Sbjct: 159 VLRLFGHFHDKDRVYLILEYVVHGELYKLLRNQKRFTESTASSYIYQMSEALLYLHGKNI 218 Query: 188 IHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPEVL 367 IHRD+KPEN+LL + IKI+DFG +V P + R T GT Y+PPE++ Sbjct: 219 IHRDIKPENILLHFNDTIKISDFGW---SVHAP--------SNRRSTLCGTMDYLPPEIV 267 Query: 368 NSAPATFGNDLWALGCTLFQMLSGSSPFKD-ASEWLIFQRIIARDLRFPEFFSDEARDLI 544 S P D+W+LG +++ L G+ PF++ ++RI+ DLR P + S +A DLI Sbjct: 268 QSRPYDKNVDVWSLGILMYEFLCGAPPFEEPGGAQATYRRIVKLDLRIPPYVSADAADLI 327 Query: 545 DKLLDVDPTK 574 ++L +DP K Sbjct: 328 KRMLTLDPAK 337
>KS6A5_MOUSE (Q8C050) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RLSK) Length = 863 Score = 126 bits (317), Expect = 4e-29 Identities = 70/197 (35%), Positives = 113/197 (57%), Gaps = 6/197 (3%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L + FQ L++ L+ GGELF + ++ R +E E + Y EIV LE+LH + Sbjct: 111 PFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHLHKL 170 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+K EN+LL S+GH+ + DFG K V ERA +F GT Y+ P+ Sbjct: 171 GIIYRDIKLENILLDSNGHVVLTDFGLSKEFV--------ADETERAYSFCGTIEYMAPD 222 Query: 362 VLNSAPATFGN--DLWALGCTLFQMLSGSSPF----KDASEWLIFQRIIARDLRFPEFFS 523 ++ + D W+LG ++++L+G+SPF + S+ I +RI+ + +P+ S Sbjct: 223 IVRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMS 282 Query: 524 DEARDLIDKLLDVDPTK 574 A+DL+ +LL DP K Sbjct: 283 TVAKDLLQRLLMKDPKK 299 Score = 109 bits (272), Expect = 6e-24 Identities = 76/206 (36%), Positives = 104/206 (50%), Gaps = 18/206 (8%) Frame = +2 Query: 11 IRLFFTFQDSYSL--YMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSVG 184 I LF D+ L ++ +E GGELF++I RK SE EA + ++V + ++H VG Sbjct: 544 IVLFILLSDNGQLHTFLVMELLNGGELFERIKRKKHFSETEASYIMRKLVSAVSHMHDVG 603 Query: 185 LIHRDVKPENLLLTSDG---HIKIADFG--SVKPTVDTPIKVLPNSTNERACTFVGTAAY 349 ++HRD+KPENLL T + IK+ DFG +KP + P+K T T Y Sbjct: 604 VVHRDLKPENLLFTDENDNLEIKVIDFGFARLKPPDNQPLK-----------TPCFTLHY 652 Query: 350 VPPEVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWL-------IFQRIIARDLRF 508 PE+L DLW+LG L+ MLSG PF+ L I ++I D F Sbjct: 653 AAPELLTHNGYDESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSF 712 Query: 509 P----EFFSDEARDLIDKLLDVDPTK 574 + S EA+DLI LL VDP K Sbjct: 713 EGEAWKNVSQEAKDLIQGLLTVDPNK 738
>IPL1_CANGA (Q6FV07) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 358 Score = 126 bits (316), Expect = 5e-29 Identities = 68/191 (35%), Positives = 104/191 (54%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +I+L+ F D +Y+ +E GEL+ + G ++ A Y +I D L Y+H Sbjct: 158 PNIIKLYAHFHDEKRVYLLMEHSINGELYKSLKNNGPFNDVLASHYIYQIADALHYMHKK 217 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +IHRDVKPEN+L+ D +K+ADFG + N + T GT Y+ PE Sbjct: 218 RIIHRDVKPENVLIGFDNVVKLADFG----------WSILNPEGSKRKTLCGTIDYLSPE 267 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ D+WALG ++++ G PF++ S+ L ++RI+ DL FPE S +A+DL Sbjct: 268 MITPREYDEQVDVWALGVLAYELVVGVPPFEENSKELTYKRILKCDLNFPESISKDAKDL 327 Query: 542 IDKLLDVDPTK 574 I KLL D T+ Sbjct: 328 ISKLLVTDTTQ 338
>SCH9_YEAST (P11792) Serine/threonine-protein kinase SCH9 (EC 2.7.11.1)| Length = 823 Score = 125 bits (315), Expect = 7e-29 Identities = 71/191 (37%), Positives = 109/191 (57%), Gaps = 2/191 (1%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L F+FQ LY+ + GGELF + ++GR SED A+FY AE+V LE+LH Sbjct: 472 PFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIAELVLALEHLHDN 531 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +++RD+KPEN+LL ++G+I + DFG K + +R TF GT Y+ PE Sbjct: 532 DIVYRDLKPENILLDANGNIALCDFGLSKADL-----------KDRTNTFCGTTEYLAPE 580 Query: 362 -VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFP-EFFSDEAR 535 +L+ T D W+LG +F+M G SPF + ++Q+I ++FP + S E R Sbjct: 581 LLLDETGYTKMVDFWSLGVLIFEMCCGWSPFFAENNQKMYQKIAFGKVKFPRDVLSQEGR 640 Query: 536 DLIDKLLDVDP 568 + LL+ +P Sbjct: 641 SFVKGLLNRNP 651
>KS6A5_PONPY (Q5R4K3) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1)| Length = 802 Score = 125 bits (315), Expect = 7e-29 Identities = 71/197 (36%), Positives = 112/197 (56%), Gaps = 6/197 (3%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L + FQ L++ L+ GGELF + ++ R +E E + Y EIV LE+LH + Sbjct: 112 PFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHLHKL 171 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+K EN+LL S+GH+ + DFG K V ERA +F GT Y+ P+ Sbjct: 172 GIIYRDIKLENILLDSNGHVMLTDFGLSKEFV--------ADETERAYSFCGTIEYMAPD 223 Query: 362 VLNSAPATFGN--DLWALGCTLFQMLSGSSPF----KDASEWLIFQRIIARDLRFPEFFS 523 ++ + D W+LG ++++L+G+SPF + S+ I +RI+ + +P+ S Sbjct: 224 IVRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMS 283 Query: 524 DEARDLIDKLLDVDPTK 574 A+DLI LL DP K Sbjct: 284 ALAKDLIQHLLMKDPKK 300 Score = 118 bits (295), Expect = 1e-26 Identities = 75/205 (36%), Positives = 104/205 (50%), Gaps = 14/205 (6%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +++L F D ++ +E GGELF++I +K SE EA + ++V + ++H V Sbjct: 479 PNIVKLHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDV 538 Query: 182 GLIHRDVKPENLLLTSDG---HIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYV 352 G++HRD+KPENLL T + IKI DFG +P K N + C T Y Sbjct: 539 GVVHRDLKPENLLFTDENDNLEIKIIDFGFARP------KPPDNQPLKTPCF---TLHYA 589 Query: 353 PPEVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWL-------IFQRIIARDLRFP 511 PE+LN DLW+LG L+ MLSG PF+ L I ++I D F Sbjct: 590 APELLNQNGYDESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFE 649 Query: 512 ----EFFSDEARDLIDKLLDVDPTK 574 + S EA+DLI LL VDP K Sbjct: 650 GEAWKNVSQEAKDLIQGLLTVDPNK 674
>JIL1_DROME (Q9V3I5) Chromosomal serine/threonine-protein kinase JIL-1 (EC| 2.7.11.1) Length = 1207 Score = 125 bits (315), Expect = 7e-29 Identities = 70/197 (35%), Positives = 106/197 (53%), Gaps = 6/197 (3%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L + FQ S LY+ L+ GGELF + E R Y AE+V LE LH + Sbjct: 324 PFLVSLHYAFQSSSKLYLVLDFANGGELFTHLYHSENFEESRVRVYIAEVVLALEQLHQL 383 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+K EN+LL +GHI ++DFG K+L RA +F GT Y+ PE Sbjct: 384 GIIYRDIKLENILLDGEGHIVLSDFGL--------SKILTAENEYRAHSFCGTLEYMAPE 435 Query: 362 VLNSAPATFGN--DLWALGCTLFQMLSGSSPFKDASEWL----IFQRIIARDLRFPEFFS 523 ++ + P + D W++G F++L+G+SPF + + I +RI P FS Sbjct: 436 IIRTGPPGHDSAVDWWSVGVLTFELLTGASPFATSDGQVQQSEISRRIQKEQPMIPSSFS 495 Query: 524 DEARDLIDKLLDVDPTK 574 ARD + K+L+ +P + Sbjct: 496 ANARDFVLKMLEKNPKR 512 Score = 61.2 bits (147), Expect = 2e-09 Identities = 48/157 (30%), Positives = 71/157 (45%), Gaps = 14/157 (8%) Frame = +2 Query: 26 TFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSVGLIHRDVK 205 TF++ ++ +E G EL I R+ ED R ++V + ++HS IH D+K Sbjct: 686 TFREKCETWIVMEYLSGPELTASI----RMDEDSCREIFLQLVMAVRHIHSKHFIHGDLK 741 Query: 206 PENLLLTS--DGHIKIADFGSV------KPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 PEN++ + D +K+ DFGS K D P L Y PPE Sbjct: 742 PENIMFENREDRTVKLIDFGSACYNNRFKSWKDKPRYTLD---------------YAPPE 786 Query: 362 VLNSA------PATFGNDLWALGCTLFQMLSGSSPFK 454 +L A PA D++ LG TL+ ML G P++ Sbjct: 787 MLADANLVTYSPAV---DIYGLGATLYTMLVGHRPYR 820
>CPK11_ARATH (O22932) CBL-interacting serine/threonine-protein kinase 11 (EC| 2.7.11.1) (SOS2-like protein kinase PKS5) (SOS-interacting protein 4) (SNF1-related kinase 3.22) Length = 435 Score = 125 bits (315), Expect = 7e-29 Identities = 64/190 (33%), Positives = 111/190 (58%), Gaps = 1/190 (0%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +++L ++ A+E +GGELF++I + GRLSED +R Y +++ + Y H+ Sbjct: 80 PNIVKLHEVMATKSKIFFAMEFVKGGELFNKISKHGRLSEDLSRRYFQQLISAVGYCHAR 139 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+ HRD+KPENLL+ +G++K++DFG T ++ P+ C GT AYV PE Sbjct: 140 GVYHRDLKPENLLIDENGNLKVSDFGLSALT----DQIRPDGLLHTLC---GTPAYVAPE 192 Query: 362 VLNSAPATFGN-DLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARD 538 +L+ D+W+ G LF +++G PF D + ++++I + RFP + S + + Sbjct: 193 ILSKKGYEGAKVDVWSCGIVLFVLVAGYLPFNDPNVMNMYKKIYKGEYRFPRWMSPDLKR 252 Query: 539 LIDKLLDVDP 568 + +LLD++P Sbjct: 253 FVSRLLDINP 262
>PLK1_CAEEL (P34331) Serine/threonine-protein kinase plk-1 (EC 2.7.11.21)| (Polo-like kinase 1) Length = 649 Score = 125 bits (314), Expect = 9e-29 Identities = 71/189 (37%), Positives = 107/189 (56%) Frame = +2 Query: 8 VIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSVGL 187 +++LF F+D+ ++Y+ LE C L + R+ ++E EAR++ +IVD + YLH + + Sbjct: 99 IVKLFNFFEDNLNVYITLELCARRSLMELHKRRKAVTEPEARYFTHQIVDGVLYLHDLNI 158 Query: 188 IHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPEVL 367 IHRD+K NL L D +KI DFG + TV + +ER T GT Y+ PEVL Sbjct: 159 IHRDMKLGNLFLNDDLVVKIGDFG-LATTV---------NGDERKKTLCGTPNYIAPEVL 208 Query: 368 NSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDLID 547 N A +F D+WA+GC L+ +L G PF+ S + RI + P + A LI Sbjct: 209 NKAGHSFEVDIWAVGCILYILLFGQPPFESKSLEETYSRIRHNNYTIPSIATQPAASLIR 268 Query: 548 KLLDVDPTK 574 K+LD +PT+ Sbjct: 269 KMLDPEPTR 277
>SCK1_SCHPO (P50530) Serine/threonine-protein kinase sck1 (EC 2.7.11.1)| Length = 696 Score = 125 bits (314), Expect = 9e-29 Identities = 74/191 (38%), Positives = 104/191 (54%), Gaps = 2/191 (1%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L F+FQ + LY+ + GGELF + +GR E A+FY AE+V LE+LH Sbjct: 363 PFIVGLKFSFQTASDLYLITDYMSGGELFWHLQHEGRFPEQRAKFYIAELVLALEHLHKH 422 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +I+RD+KPEN+LL +DGHI + DFG K + S N TF GT Y+ PE Sbjct: 423 DIIYRDLKPENILLDADGHIALCDFGLSKANL---------SANATTNTFCGTTEYLAPE 473 Query: 362 V-LNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPE-FFSDEAR 535 V L T D W+LG +F+M G SPF +++ I +RFP+ S E R Sbjct: 474 VLLEDKGYTKQVDFWSLGVLVFEMCCGWSPFYAPDVQQMYRNIAFGKVRFPKGVLSSEGR 533 Query: 536 DLIDKLLDVDP 568 + LL+ +P Sbjct: 534 SFVRGLLNRNP 544
>KAPC_ENCCU (Q8SRK8) Probable cAMP-dependent protein kinase catalytic subunit| (EC 2.7.11.11) Length = 322 Score = 125 bits (314), Expect = 9e-29 Identities = 71/186 (38%), Positives = 101/186 (54%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P V +L+ T + + +E GGELF + + GR E ARFYAAEI+ L ++H Sbjct: 67 PFVAKLYSTDFHGGKVGLIMEYVGGGELFYWLKKCGRFDEQMARFYAAEIISALRFIHGR 126 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+++RD+KPEN+L+TS GHIK+ DFG +E GT Y+ PE Sbjct: 127 GILYRDLKPENILITSTGHIKLIDFG------------FSVYESENIYMISGTPEYMSPE 174 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 L S +D W LG +++ML G PF D+S I+ +I+ ++ FP + S AR L Sbjct: 175 KLRSEDDGRASDYWGLGVMIYEMLCGDPPFYDSSADAIYHKILESNVVFPHYVSPVARCL 234 Query: 542 IDKLLD 559 I LLD Sbjct: 235 ITGLLD 240
>KPC1_CAEEL (P34722) Protein kinase C-like 1 (EC 2.7.11.13) (PKC)| (Tetradecanoyl phorbol acetate resistant protein 1) Length = 704 Score = 125 bits (313), Expect = 1e-28 Identities = 69/189 (36%), Positives = 100/189 (52%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + +LF +FQ + L+ +E GG+L I + + E RFYA EIV L++LH+ Sbjct: 434 PFLCQLFCSFQTNEYLFFVMEYLNGGDLMHHIQQIKKFDEARTRFYACEIVVALQFLHTN 493 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +I+RD+K +N+LL DGHIK+ADFG K + N N A TF GT Y+ PE Sbjct: 494 NIIYRDLKLDNVLLDCDGHIKLADFGMAKTEM--------NRENGMASTFCGTPDYISPE 545 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ D W+ G +++ML G SPF E +F I+ FP+ S EA Sbjct: 546 IIKGQLYNEAVDFWSFGVLMYEMLVGQSPFHGEGEDELFDSILNERPYFPKTISKEAAKC 605 Query: 542 IDKLLDVDP 568 + L D +P Sbjct: 606 LSALFDRNP 614
>AKT2_CAEEL (Q9XTG7) Serine/threonine-protein kinase akt-2 (EC 2.7.11.1)| (Protein kinase B akt-2) (PKB akt-2) Length = 528 Score = 125 bits (313), Expect = 1e-28 Identities = 70/191 (36%), Positives = 97/191 (50%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + L ++FQ Y + +E GGELF + R SE RFY +EI+ L YLH Sbjct: 238 PFLTLLKYSFQAQYHICFVMEFANGGELFTHLQRCKTFSEARTRFYGSEIILALGYLHHR 297 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +++RD+K ENLLL DGHIKI DFG K + ++ TF GT Y+ PE Sbjct: 298 NIVYRDMKLENLLLDRDGHIKITDFGLCKEEI---------KYGDKTSTFCGTPEYLAPE 348 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 V+ D W +G +++M+ G PF +F+ I DL+FP S EA L Sbjct: 349 VIEDIDYDRSVDWWGVGVVMYEMMCGRLPFSAKENGKLFELITTCDLKFPNRLSPEAVTL 408 Query: 542 IDKLLDVDPTK 574 + LL+ P K Sbjct: 409 LSGLLERVPAK 419
>KPCI_PONPY (Q5R4K9) Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota)| Length = 587 Score = 125 bits (313), Expect = 1e-28 Identities = 72/198 (36%), Positives = 106/198 (53%), Gaps = 9/198 (4%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L FQ L+ +E GG+L + R+ +L E+ ARFY+AEI L YLH Sbjct: 304 PFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHER 363 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+K +N+LL S+GHIK+ D+G K + P T TF GT Y+ PE Sbjct: 364 GIIYRDLKLDNVLLDSEGHIKLTDYGMCKE------GLRPGDTTS---TFCGTPNYIAPE 414 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPF---------KDASEWLIFQRIIARDLRFPE 514 +L F D WALG +F+M++G SPF +E +FQ I+ + +R P Sbjct: 415 ILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPR 474 Query: 515 FFSDEARDLIDKLLDVDP 568 S +A ++ L+ DP Sbjct: 475 SLSVKAASVLKSFLNKDP 492
>KPCI_HUMAN (P41743) Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota)| (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (PRKC-lambda/iota) Length = 587 Score = 125 bits (313), Expect = 1e-28 Identities = 72/198 (36%), Positives = 106/198 (53%), Gaps = 9/198 (4%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L FQ L+ +E GG+L + R+ +L E+ ARFY+AEI L YLH Sbjct: 304 PFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHER 363 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+K +N+LL S+GHIK+ D+G K + P T TF GT Y+ PE Sbjct: 364 GIIYRDLKLDNVLLDSEGHIKLTDYGMCKE------GLRPGDTTS---TFCGTPNYIAPE 414 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPF---------KDASEWLIFQRIIARDLRFPE 514 +L F D WALG +F+M++G SPF +E +FQ I+ + +R P Sbjct: 415 ILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPR 474 Query: 515 FFSDEARDLIDKLLDVDP 568 S +A ++ L+ DP Sbjct: 475 SLSVKAASVLKSFLNKDP 492
>KPCI_MOUSE (Q62074) Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota)| (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) Length = 586 Score = 125 bits (313), Expect = 1e-28 Identities = 72/198 (36%), Positives = 106/198 (53%), Gaps = 9/198 (4%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L FQ L+ +E GG+L + R+ +L E+ ARFY+AEI L YLH Sbjct: 303 PFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHER 362 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+K +N+LL S+GHIK+ D+G K + P T TF GT Y+ PE Sbjct: 363 GIIYRDLKLDNVLLDSEGHIKLTDYGMCKE------GLRPGDTTS---TFCGTPNYIAPE 413 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPF---------KDASEWLIFQRIIARDLRFPE 514 +L F D WALG +F+M++G SPF +E +FQ I+ + +R P Sbjct: 414 ILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPR 473 Query: 515 FFSDEARDLIDKLLDVDP 568 S +A ++ L+ DP Sbjct: 474 SLSVKAASVLKSFLNKDP 491
>KGP1A_RABIT (O77676) cGMP-dependent protein kinase 1, alpha isozyme (EC| 2.7.11.12) (CGK 1 alpha) (cGKI-alpha) Length = 670 Score = 124 bits (312), Expect = 1e-28 Identities = 69/192 (35%), Positives = 106/192 (55%), Gaps = 3/192 (1%) Frame = +2 Query: 8 VIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSVGL 187 ++RL+ TF+DS LYM +E+C GGEL+ + +G + RFY A +V+ YLHS G+ Sbjct: 420 IVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGI 479 Query: 188 IHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPEVL 367 I+RD+KPENL+L G+ K+ DFG K ++ TF GT YV PE++ Sbjct: 480 IYRDLKPENLILDHRGYAKLVDFGFAKKI----------GFGKKTWTFCGTPEYVAPEII 529 Query: 368 NSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARD---LRFPEFFSDEARD 538 + D W+LG ++++L+GS PF + II R + FP+ + A + Sbjct: 530 LNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTY-NIILRGIDMIEFPKKIAKNAAN 588 Query: 539 LIDKLLDVDPTK 574 LI KL +P++ Sbjct: 589 LIKKLCRDNPSE 600
>KGP1A_HUMAN (Q13976) cGMP-dependent protein kinase 1, alpha isozyme (EC| 2.7.11.12) (CGK 1 alpha) (cGKI-alpha) Length = 670 Score = 124 bits (312), Expect = 1e-28 Identities = 69/192 (35%), Positives = 106/192 (55%), Gaps = 3/192 (1%) Frame = +2 Query: 8 VIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSVGL 187 ++RL+ TF+DS LYM +E+C GGEL+ + +G + RFY A +V+ YLHS G+ Sbjct: 420 IVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGI 479 Query: 188 IHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPEVL 367 I+RD+KPENL+L G+ K+ DFG K ++ TF GT YV PE++ Sbjct: 480 IYRDLKPENLILDHRGYAKLVDFGFAKKI----------GFGKKTWTFCGTPEYVAPEII 529 Query: 368 NSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARD---LRFPEFFSDEARD 538 + D W+LG ++++L+GS PF + II R + FP+ + A + Sbjct: 530 LNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTY-NIILRGIDMIEFPKKIAKNAAN 588 Query: 539 LIDKLLDVDPTK 574 LI KL +P++ Sbjct: 589 LIKKLCRDNPSE 600
>KGP1A_BOVIN (P00516) cGMP-dependent protein kinase 1, alpha isozyme (EC| 2.7.11.12) (CGK 1 alpha) (cGKI-alpha) Length = 670 Score = 124 bits (312), Expect = 1e-28 Identities = 69/192 (35%), Positives = 106/192 (55%), Gaps = 3/192 (1%) Frame = +2 Query: 8 VIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSVGL 187 ++RL+ TF+DS LYM +E+C GGEL+ + +G + RFY A +V+ YLHS G+ Sbjct: 420 IVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGI 479 Query: 188 IHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPEVL 367 I+RD+KPENL+L G+ K+ DFG K ++ TF GT YV PE++ Sbjct: 480 IYRDLKPENLILDHRGYAKLVDFGFAKKI----------GFGKKTWTFCGTPEYVAPEII 529 Query: 368 NSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARD---LRFPEFFSDEARD 538 + D W+LG ++++L+GS PF + II R + FP+ + A + Sbjct: 530 LNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTY-NIILRGIDMIEFPKKIAKNAAN 588 Query: 539 LIDKLLDVDPTK 574 LI KL +P++ Sbjct: 589 LIKKLCRDNPSE 600
>KGP1B_MOUSE (Q9Z0Z0) cGMP-dependent protein kinase 1, beta isozyme (EC| 2.7.11.12) (cGK 1 beta) (cGKI-beta) Length = 686 Score = 124 bits (312), Expect = 1e-28 Identities = 69/192 (35%), Positives = 106/192 (55%), Gaps = 3/192 (1%) Frame = +2 Query: 8 VIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSVGL 187 ++RL+ TF+DS LYM +E+C GGEL+ + +G + RFY A +V+ YLHS G+ Sbjct: 436 IVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGI 495 Query: 188 IHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPEVL 367 I+RD+KPENL+L G+ K+ DFG K ++ TF GT YV PE++ Sbjct: 496 IYRDLKPENLILDHRGYAKLVDFGFAKKI----------GFGKKTWTFCGTPEYVAPEII 545 Query: 368 NSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARD---LRFPEFFSDEARD 538 + D W+LG ++++L+GS PF + II R + FP+ + A + Sbjct: 546 LNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTY-NIILRGIDMIEFPKKIAKNAAN 604 Query: 539 LIDKLLDVDPTK 574 LI KL +P++ Sbjct: 605 LIKKLCRDNPSE 616
>KGP1B_HUMAN (P14619) cGMP-dependent protein kinase 1, beta isozyme (EC| 2.7.11.12) (cGK 1 beta) (cGKI-beta) Length = 686 Score = 124 bits (312), Expect = 1e-28 Identities = 69/192 (35%), Positives = 106/192 (55%), Gaps = 3/192 (1%) Frame = +2 Query: 8 VIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSVGL 187 ++RL+ TF+DS LYM +E+C GGEL+ + +G + RFY A +V+ YLHS G+ Sbjct: 436 IVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGI 495 Query: 188 IHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPEVL 367 I+RD+KPENL+L G+ K+ DFG K ++ TF GT YV PE++ Sbjct: 496 IYRDLKPENLILDHRGYAKLVDFGFAKKI----------GFGKKTWTFCGTPEYVAPEII 545 Query: 368 NSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARD---LRFPEFFSDEARD 538 + D W+LG ++++L+GS PF + II R + FP+ + A + Sbjct: 546 LNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTY-NIILRGIDMIEFPKKIAKNAAN 604 Query: 539 LIDKLLDVDPTK 574 LI KL +P++ Sbjct: 605 LIKKLCRDNPSE 616
>KGP1B_BOVIN (P21136) cGMP-dependent protein kinase 1, beta isozyme (EC| 2.7.11.12) (cGK 1 beta) (cGKI-beta) Length = 686 Score = 124 bits (312), Expect = 1e-28 Identities = 69/192 (35%), Positives = 106/192 (55%), Gaps = 3/192 (1%) Frame = +2 Query: 8 VIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSVGL 187 ++RL+ TF+DS LYM +E+C GGEL+ + +G + RFY A +V+ YLHS G+ Sbjct: 436 IVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGI 495 Query: 188 IHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPEVL 367 I+RD+KPENL+L G+ K+ DFG K ++ TF GT YV PE++ Sbjct: 496 IYRDLKPENLILDHRGYAKLVDFGFAKKI----------GFGKKTWTFCGTPEYVAPEII 545 Query: 368 NSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARD---LRFPEFFSDEARD 538 + D W+LG ++++L+GS PF + II R + FP+ + A + Sbjct: 546 LNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTY-NIILRGIDMIEFPKKIAKNAAN 604 Query: 539 LIDKLLDVDPTK 574 LI KL +P++ Sbjct: 605 LIKKLCRDNPSE 616
>KPC2_APLCA (Q16975) Calcium-independent protein kinase C (EC 2.7.11.13) (APL II)| Length = 743 Score = 124 bits (312), Expect = 1e-28 Identities = 68/191 (35%), Positives = 105/191 (54%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + L +FQ L+ +E GG+L QI R + E ARFYAAE+ L +LH Sbjct: 462 PFLTALHSSFQTKERLFFVMEYVNGGDLMFQIQRARKFDEPRARFYAAEVTLALMFLHRH 521 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+K +N+LL ++GH KIADFG K + + N+ TF GT Y+ PE Sbjct: 522 GIIYRDLKLDNILLDAEGHCKIADFGMCKEGM---------TENKLTQTFCGTPDYIAPE 572 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 +L D WALG +++M++G PF+ +E +F+ I+ D+ +P + S EA + Sbjct: 573 ILQELKYDASVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSI 632 Query: 542 IDKLLDVDPTK 574 + + +P K Sbjct: 633 LKGFMTKNPAK 643
>KIN10_ARATH (Q38997) SNF1-related protein kinase catalytic alpha subunit KIN10| (EC 2.7.11.1) (AKIN10) (AKIN alpha2) Length = 535 Score = 124 bits (312), Expect = 1e-28 Identities = 75/192 (39%), Positives = 103/192 (53%), Gaps = 1/192 (0%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +IRL+ + +Y+ +E GELFD IV KGRL EDEAR + +I+ +EY H Sbjct: 100 PHIIRLYEVIETPTDIYLVMEYVNSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHRN 159 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTP-IKVLPNSTNERACTFVGTAAYVPP 358 ++HRD+KPENLLL S ++KIADFG D +K S N A + Y P Sbjct: 160 MVVHRDLKPENLLLDSKCNVKIADFGLSNIMRDGHFLKTSCGSPNYAAPEVISGKLYAGP 219 Query: 359 EVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARD 538 EV D+W+ G L+ +L G+ PF D + +F++I P S ARD Sbjct: 220 EV----------DVWSCGVILYALLCGTLPFDDENIPNLFKKIKGGIYTLPSHLSPGARD 269 Query: 539 LIDKLLDVDPTK 574 LI ++L VDP K Sbjct: 270 LIPRMLVVDPMK 281
>KPCT_HUMAN (Q04759) Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)| Length = 706 Score = 124 bits (311), Expect = 2e-28 Identities = 73/191 (38%), Positives = 102/191 (53%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + +F TFQ +L+ +E GG+L I + A FYAAEI+ L++LHS Sbjct: 439 PFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSK 498 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+++RD+K +N+LL DGHIKIADFG K + K TN TF GT Y+ PE Sbjct: 499 GIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAK-----TN----TFCGTPDYIAPE 549 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 +L D W+ G L++ML G SPF E +F I + +P + EA+DL Sbjct: 550 ILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWLEKEAKDL 609 Query: 542 IDKLLDVDPTK 574 + KL +P K Sbjct: 610 LVKLFVREPEK 620
>IPL1_ASHGO (Q755C4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 367 Score = 124 bits (311), Expect = 2e-28 Identities = 64/189 (33%), Positives = 107/189 (56%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + +L+ F D +Y+ +E GEL+ + + ++ A +Y ++ D L+Y+H Sbjct: 167 PNLTQLYGYFHDEKRVYLLMEYLVNGELYKHLKGRSHFNDVVASYYVYQMADALDYMHER 226 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 ++HRD+KPEN+++ + IK+ DFG +V TP + T GT Y+ PE Sbjct: 227 NILHRDIKPENIIIGFNNTIKLTDFGW---SVITP-------KGSKRKTLCGTVDYLSPE 276 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ S D+WALG +++L GS PF++ S+ L ++RI+ R+L FP+ EAR L Sbjct: 277 LIRSREYNEKVDVWALGVLTYELLVGSPPFEEESKELTYKRILKRNLIFPDHVDTEARHL 336 Query: 542 IDKLLDVDP 568 I +LL+ DP Sbjct: 337 ISRLLEYDP 345
>KPCL_MOUSE (P23298) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 683 Score = 124 bits (311), Expect = 2e-28 Identities = 66/190 (34%), Positives = 104/190 (54%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + +LF FQ L+ +E GG+L I + R E ARFYAAEI+ L +LH Sbjct: 414 PFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHEK 473 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+K +N+LL +GH K+ADFG K + + TF GT Y+ PE Sbjct: 474 GIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGV---------TTATFCGTPDYIAPE 524 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 +L D WA+G L++ML G +PF+ +E +F+ I+ ++ +P + ++AR + Sbjct: 525 ILQEMLYGPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHEDARGI 584 Query: 542 IDKLLDVDPT 571 + + +PT Sbjct: 585 LKSFMTKNPT 594
>CDPK_SOYBN (P28583) Calcium-dependent protein kinase SK5 (EC 2.7.11.1) (CDPK)| Length = 508 Score = 124 bits (310), Expect = 2e-28 Identities = 77/194 (39%), Positives = 111/194 (57%), Gaps = 7/194 (3%) Frame = +2 Query: 8 VIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSVGL 187 V+R+ T++DS ++++ +E CEGGELFD+IV+KG SE +A IV+++E HS+G+ Sbjct: 95 VVRIEGTYEDSTAVHLVMELCEGGELFDRIVQKGHYSERQAARLIKTIVEVVEACHSLGV 154 Query: 188 IHRDVKPENLL---LTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPP 358 +HRD+KPEN L + D +K DFG + V E C VG+ YV P Sbjct: 155 MHRDLKPENFLFDTIDEDAKLKATDFG---------LSVF-YKPGESFCDVVGSPYYVAP 204 Query: 359 EVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPE----FFSD 526 EVL +D+W+ G L+ +LSG PF SE IF++I+ L F SD Sbjct: 205 EVLRKLYGP-ESDVWSAGVILYILLSGVPPFWAESEPGIFRQILLGKLDFHSEPWPSISD 263 Query: 527 EARDLIDKLLDVDP 568 A+DLI K+LD +P Sbjct: 264 SAKDLIRKMLDQNP 277
>SGK3_HUMAN (Q96BR1) Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid-regulated kinase-like) Length = 496 Score = 124 bits (310), Expect = 2e-28 Identities = 70/190 (36%), Positives = 105/190 (55%), Gaps = 2/190 (1%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L ++FQ + LY L+ GGELF + R+ E ARFYAAEI L YLHS+ Sbjct: 221 PFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSI 280 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +++RD+KPEN+LL S GH+ + DFG K + + ++ TF GT Y+ PE Sbjct: 281 KIVYRDLKPENILLDSVGHVVLTDFGLCKEGI---------AISDTTTTFCGTPEYLAPE 331 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPF--KDASEWLIFQRIIARDLRFPEFFSDEAR 535 V+ P D W LG L++ML G PF +D +E ++ I+ + L S A Sbjct: 332 VIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAE--MYDNILHKPLSLRPGVSLTAW 389 Query: 536 DLIDKLLDVD 565 ++++LL+ D Sbjct: 390 SILEELLEKD 399
>AURKC_HUMAN (Q9UQB9) Serine/threonine-protein kinase 13 (EC 2.7.11.1)| (Aurora/Ipl1/Eg2 protein 2) (Aurora/Ipl1-related kinase 3) (Aurora-C) Length = 309 Score = 123 bits (309), Expect = 3e-28 Identities = 71/189 (37%), Positives = 101/189 (53%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++RL+ F D+ +Y+ LE GEL+ ++ + +L E E+ D L Y H Sbjct: 101 PNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDK 160 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +IHRD+KPENLLL G +KIADFG +V TP + R T GT Y+PPE Sbjct: 161 KVIHRDIKPENLLLGFRGEVKIADFGW---SVHTP--------SLRRKTMCGTLDYLPPE 209 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ DLW +G +++L G PF+ AS ++RI+ D+RFP ARDL Sbjct: 210 MIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDL 269 Query: 542 IDKLLDVDP 568 I +LL P Sbjct: 270 ISRLLRYQP 278
>CIPK1_ORYSA (Q6X4A2) CIPK-like protein 1 (EC 2.7.11.1) (OsCK1)| Length = 449 Score = 123 bits (308), Expect = 4e-28 Identities = 69/191 (36%), Positives = 107/191 (56%), Gaps = 1/191 (0%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P V+RLF +++ LE GGELF+ I GRL E+EAR Y ++++ ++Y HS Sbjct: 78 PNVVRLFEVMGSKARIFIVLEYVTGGELFEIIATNGRLKEEEARKYFQQLINAVDYCHSR 137 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+ HRD+K ENLLL + G++K++DFG T L ++T GT YV PE Sbjct: 138 GVYHRDLKLENLLLDASGNLKVSDFGLSALTEQVKADGLLHTT-------CGTPNYVAPE 190 Query: 362 VLNSAPAT-FGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARD 538 V+ D+W+ G L+ +L+G PF+D + ++++I P +FS A+ Sbjct: 191 VIEDRGYDGAAADIWSCGVILYVLLAGFLPFEDDNIIALYKKISEAQFTCPSWFSTGAKK 250 Query: 539 LIDKLLDVDPT 571 LI ++LD +PT Sbjct: 251 LITRILDPNPT 261
>SCK2_SCHPO (Q10364) Serine/threonine-protein kinase sck2 (EC 2.7.11.1)| Length = 646 Score = 123 bits (308), Expect = 4e-28 Identities = 73/191 (38%), Positives = 105/191 (54%), Gaps = 2/191 (1%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L F+FQ LY+ + GGELF + + R E+ A+FY AE++ L+ LH Sbjct: 327 PFIVALRFSFQTPKDLYLVTDYMAGGELFWHLQKSVRFPEERAKFYIAELLLALQALHKR 386 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+++RD+KPEN+LL GHI + DFG K + S TF GT Y+ PE Sbjct: 387 GIVYRDLKPENILLDVQGHIALCDFGLSKANL---------SVGTTTRTFCGTTDYLAPE 437 Query: 362 V-LNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPE-FFSDEAR 535 V L+ A D W+LG L++M G SPF + +++ I+ +RFP S EAR Sbjct: 438 VILDEAGYDMMVDFWSLGVLLYEMTCGWSPFYADNTQQLYKNIVFGKVRFPRGLLSVEAR 497 Query: 536 DLIDKLLDVDP 568 DLI LL+ +P Sbjct: 498 DLIKLLLNRNP 508
>KPCE_MOUSE (P16054) Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon)| Length = 737 Score = 122 bits (307), Expect = 6e-28 Identities = 65/191 (34%), Positives = 104/191 (54%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + +L+ FQ L+ +E GG+L QI R + E +RFYAAE+ L +LH Sbjct: 467 PYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQH 526 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+K +N+LL ++GH K+ADFG K + + TF GT Y+ PE Sbjct: 527 GVIYRDLKLDNILLDAEGHCKLADFGMCKEGIMNGV---------TTTTFCGTPDYIAPE 577 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 +L D WALG +++M++G PF+ +E +F+ I+ D+ +P + S EA + Sbjct: 578 ILQELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSI 637 Query: 542 IDKLLDVDPTK 574 + + +P K Sbjct: 638 LKAFMTKNPHK 648
>KPC1_APLCA (Q16974) Calcium-dependent protein kinase C (EC 2.7.11.13) (APL I)| Length = 649 Score = 122 bits (307), Expect = 6e-28 Identities = 70/191 (36%), Positives = 103/191 (53%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +++L FQ LY +E GG+L +I ++G+ E A FYAAEI L YLH+ Sbjct: 379 PFLVQLHSCFQTMDRLYFVMEYVNGGDLMYRIQQEGKFKEPVAAFYAAEIAIGLFYLHTQ 438 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+++RD+K +N++L ++GHIKIADFG K + ++ TF GT Y+ PE Sbjct: 439 GIVYRDLKLDNVMLDAEGHIKIADFGMCKENI---------MGDKTTRTFCGTPDYIAPE 489 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ P D WA G L++ML+G PF E +F I ++ +P+ S EA L Sbjct: 490 IVLYQPYGRSVDWWAYGVLLYEMLAGQPPFDGEDEEELFTSITDHNVSYPKALSREAVSL 549 Query: 542 IDKLLDVDPTK 574 LL P K Sbjct: 550 CKGLLTKTPAK 560
>SGK3_MOUSE (Q9ERE3) Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid-regulated kinase-like) (Cytokine independent survival kinase) Length = 496 Score = 122 bits (307), Expect = 6e-28 Identities = 69/188 (36%), Positives = 104/188 (55%), Gaps = 2/188 (1%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L ++FQ + LY L+ GGELF + R+ E ARFYAAEI L YLHS+ Sbjct: 221 PFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEPRARFYAAEIASALGYLHSI 280 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +++RD+KPEN+LL S GH+ + DFG K + + ++ TF GT Y+ PE Sbjct: 281 KIVYRDLKPENILLDSMGHVVLTDFGLCKEGI---------AISDTTTTFCGTPEYLAPE 331 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPF--KDASEWLIFQRIIARDLRFPEFFSDEAR 535 V+ P D W LG L++ML G PF +D +E ++ I+ + L S A Sbjct: 332 VIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAE--MYDNILHKPLNLRPGVSLTAW 389 Query: 536 DLIDKLLD 559 ++++LL+ Sbjct: 390 SILEELLE 397
>KPCG_BOVIN (P05128) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| (Fragment) Length = 682 Score = 122 bits (306), Expect = 7e-28 Identities = 71/187 (37%), Positives = 100/187 (53%) Frame = +2 Query: 14 RLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSVGLIH 193 +L TFQ LY +E GG+L I + G+ E A FYAAEI L +LH+ G+I+ Sbjct: 404 QLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIGLFFLHNQGIIY 463 Query: 194 RDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPEVLNS 373 RD+K +N++L ++GHIKI DFG K V P ST TF GT Y+ PE++ Sbjct: 464 RDLKLDNVMLDAEGHIKITDFGMCKE------NVFPGSTTR---TFCGTPDYIAPEIIAY 514 Query: 374 APATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDLIDKL 553 P D W+ G L++ML+G PF E +FQ I+ + + +P+ S EA + Sbjct: 515 QPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSREAVAICKGF 574 Query: 554 LDVDPTK 574 L P K Sbjct: 575 LTKHPAK 581
>KPCE_RABIT (P10830) Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon)| Length = 736 Score = 122 bits (306), Expect = 7e-28 Identities = 65/191 (34%), Positives = 104/191 (54%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + +L+ FQ L+ +E GG+L QI R + E +RFYAAE+ L +LH Sbjct: 466 PYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQH 525 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+K +N+LL ++GH K+ADFG K + + TF GT Y+ PE Sbjct: 526 GVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGV---------TTTTFCGTPDYIAPE 576 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 +L D WALG +++M++G PF+ +E +F+ I+ D+ +P + S EA + Sbjct: 577 ILQELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSI 636 Query: 542 IDKLLDVDPTK 574 + + +P K Sbjct: 637 LKAFMTKNPHK 647
>KPCE_HUMAN (Q02156) Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon)| Length = 737 Score = 122 bits (306), Expect = 7e-28 Identities = 65/191 (34%), Positives = 104/191 (54%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + +L+ FQ L+ +E GG+L QI R + E +RFYAAE+ L +LH Sbjct: 467 PYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQH 526 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+K +N+LL ++GH K+ADFG K + + TF GT Y+ PE Sbjct: 527 GVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGV---------TTTTFCGTPDYIAPE 577 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 +L D WALG +++M++G PF+ +E +F+ I+ D+ +P + S EA + Sbjct: 578 ILQELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSI 637 Query: 542 IDKLLDVDPTK 574 + + +P K Sbjct: 638 LKAFMTKNPHK 648
>KPCT_MOUSE (Q02111) Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)| Length = 707 Score = 122 bits (305), Expect = 9e-28 Identities = 71/191 (37%), Positives = 102/191 (53%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + +F TFQ +L+ +E GG+L I + A FYAAE++ L++LHS Sbjct: 439 PFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEVILGLQFLHSK 498 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+++RD+K +N+LL DGHIKIADFG K + K TN TF GT Y+ PE Sbjct: 499 GIVYRDLKLDNILLDRDGHIKIADFGMCKENMLGDAK-----TN----TFCGTPDYIAPE 549 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 +L D W+ G +++ML G SPF E +F I + +P + EA+DL Sbjct: 550 ILLGQKYNHSVDWWSFGVLVYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWLEREAKDL 609 Query: 542 IDKLLDVDPTK 574 + KL +P K Sbjct: 610 LVKLFVREPEK 620
>KPC2_DROME (P13677) Protein kinase C, eye isozyme (EC 2.7.11.13) (PKC)| (dPKC53E(EY)) (Protein INAC) (Inactivation no after-potential C protein) (Photoreceptor-specific PKC) (Eye-PKC) Length = 700 Score = 122 bits (305), Expect = 9e-28 Identities = 64/189 (33%), Positives = 101/189 (53%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ + FQ L+ +E C+GG+L + + GR E A FYA E+ L +LH Sbjct: 430 PFLVSMHSCFQTMDRLFFVMEYCKGGDLMYHMQQYGRFKESVAIFYAVEVAIALFFLHER 489 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +I+RD+K +N+LL +GH+K+ DFG K V + + TF GT Y+ PE Sbjct: 490 DIIYRDLKLDNILLDGEGHVKLVDFGLSKEGV---------TERQTTRTFCGTPNYMAPE 540 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 +++ P + D W+ G LF+ ++G +PF+ E +F+ I + FP+ FS EA D+ Sbjct: 541 IVSYDPYSIAADWWSFGVLLFEFMAGQAPFEGDDETTVFRNIKDKKAVFPKHFSVEAMDI 600 Query: 542 IDKLLDVDP 568 I L P Sbjct: 601 ITSFLTKKP 609
>KPCL_HUMAN (P24723) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 682 Score = 122 bits (305), Expect = 9e-28 Identities = 65/190 (34%), Positives = 103/190 (54%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + +LF FQ L+ +E GG+L I + R E ARFYAAEI+ L +LH Sbjct: 413 PFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHDK 472 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+K +N+LL +GH K+ADFG K + + TF GT Y+ PE Sbjct: 473 GIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGV---------TTATFCGTPDYIAPE 523 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 +L D WA+G L++ML G +PF+ +E +F+ I+ ++ +P + ++A + Sbjct: 524 ILQEMLYGPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHEDATGI 583 Query: 542 IDKLLDVDPT 571 + + +PT Sbjct: 584 LKSFMTKNPT 593
>KPC2_CAEEL (P90980) Protein kinase C-like 2 (EC 2.7.11.13) (PKC2)| Length = 682 Score = 122 bits (305), Expect = 9e-28 Identities = 73/189 (38%), Positives = 102/189 (53%) Frame = +2 Query: 8 VIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSVGL 187 ++ L FQ LY +E GG+L QI + G+ E A FYAAEI L +LHS G+ Sbjct: 409 LVALHSCFQTMDRLYFVMEFVNGGDLMYQIQQVGKFKEPVAVFYAAEIAVGLFFLHSKGI 468 Query: 188 IHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPEVL 367 I+RD+K +N++L DGHIKI DFG K + ++T + TF GT Y+ PE++ Sbjct: 469 IYRDLKLDNVMLERDGHIKITDFGMCKE------NIFGDATTK---TFCGTPDYIAPEII 519 Query: 368 NSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDLID 547 P D WA G LF+ML+G PF E +F I ++ +P+ S EA L Sbjct: 520 LYQPYGKSVDWWAYGVLLFEMLAGQPPFDGEDEDELFTAITEHNVSYPKSLSKEAVSLCK 579 Query: 548 KLLDVDPTK 574 LL +P+K Sbjct: 580 ALLIKNPSK 588
>KPCL_RAT (Q64617) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 683 Score = 122 bits (305), Expect = 9e-28 Identities = 65/190 (34%), Positives = 103/190 (54%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + +LF FQ L+ +E GG+L I + R E ARFYAAEI+ L +LH Sbjct: 414 PFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHEK 473 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+K +N+LL +GH K+ADFG K + + TF GT Y+ PE Sbjct: 474 GIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGV---------TTATFCGTPDYIAPE 524 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 +L D WA+G L++ML G +PF+ +E +F+ I+ ++ +P + ++A + Sbjct: 525 ILQEMLYGPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHEDATGI 584 Query: 542 IDKLLDVDPT 571 + + +PT Sbjct: 585 LKSFMTKNPT 594
>STK6_HUMAN (O14965) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1) (Aurora-related kinase 1) (hARK1) (Aurora-A) (Breast-tumor-amplified kinase) Length = 403 Score = 121 bits (304), Expect = 1e-27 Identities = 67/191 (35%), Positives = 104/191 (54%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++RL+ F D+ +Y+ LE G ++ ++ + + E Y E+ + L Y HS Sbjct: 191 PNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSK 250 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +IHRD+KPENLLL S G +KIADFG +V P + R T GT Y+PPE Sbjct: 251 RVIHRDIKPENLLLGSAGELKIADFGW---SVHAP--------SSRRTTLCGTLDYLPPE 299 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ DLW+LG ++ L G PF+ + ++RI + FP+F ++ ARDL Sbjct: 300 MIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDL 359 Query: 542 IDKLLDVDPTK 574 I +LL +P++ Sbjct: 360 ISRLLKHNPSQ 370
>MYLK_DICDI (P25323) Myosin light chain kinase (EC 2.7.11.18) (MLCK)| Length = 295 Score = 121 bits (304), Expect = 1e-27 Identities = 79/198 (39%), Positives = 110/198 (55%), Gaps = 7/198 (3%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +I L F LY+ +E GGELFD+IV KG SE +A +IV + YLH + Sbjct: 65 PNIIALKELFDTPEKLYLVMELVTGGELFDKIVEKGSYSEADAANLVKKIVSAVGYLHGL 124 Query: 182 GLIHRDVKPENLLLTS-DGHIK--IADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYV 352 ++HRD+KPENLLL S + H++ IADFG K T + + AC GT +YV Sbjct: 125 NIVHRDLKPENLLLKSKENHLEVAIADFGLSKIIGQTLVM-------QTAC---GTPSYV 174 Query: 353 PPEVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFF---- 520 PEVLN+ D+W++G + +L G PF + IF++I+ + FPE + Sbjct: 175 APEVLNATGYDKEVDMWSIGVITYILLCGFPPFYGDTVPEIFEQIMEANYEFPEEYWGGI 234 Query: 521 SDEARDLIDKLLDVDPTK 574 S EA+D I KLL VD +K Sbjct: 235 SKEAKDFIGKLLVVDVSK 252
>KCC1A_RAT (Q63450) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 374 Score = 121 bits (304), Expect = 1e-27 Identities = 71/198 (35%), Positives = 109/198 (55%), Gaps = 7/198 (3%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L ++ LY+ ++ GGELFD+IV KG +E +A +++D ++YLH + Sbjct: 76 PNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDL 135 Query: 182 GLIHRDVKPENLL---LTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYV 352 G++HRD+KPENLL L D I I+DFG K ++ P VL T GT YV Sbjct: 136 GIVHRDLKPENLLYYSLDEDSKIMISDFGLSK--MEDPGSVL--------STACGTPGYV 185 Query: 353 PPEVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFP----EFF 520 PEVL P + D W++G + +L G PF D ++ +F++I+ + F + Sbjct: 186 APEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDI 245 Query: 521 SDEARDLIDKLLDVDPTK 574 SD A+D I L++ DP K Sbjct: 246 SDSAKDFIRHLMEKDPEK 263
>KCC1A_MOUSE (Q91YS8) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 374 Score = 121 bits (304), Expect = 1e-27 Identities = 71/198 (35%), Positives = 109/198 (55%), Gaps = 7/198 (3%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L ++ LY+ ++ GGELFD+IV KG +E +A +++D ++YLH + Sbjct: 76 PNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDL 135 Query: 182 GLIHRDVKPENLL---LTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYV 352 G++HRD+KPENLL L D I I+DFG K ++ P VL T GT YV Sbjct: 136 GIVHRDLKPENLLYYSLDEDSKIMISDFGLSK--MEDPGSVL--------STACGTPGYV 185 Query: 353 PPEVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFP----EFF 520 PEVL P + D W++G + +L G PF D ++ +F++I+ + F + Sbjct: 186 APEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDI 245 Query: 521 SDEARDLIDKLLDVDPTK 574 SD A+D I L++ DP K Sbjct: 246 SDSAKDFIRHLMEKDPEK 263
>KPCG_RAT (P63319) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 121 bits (304), Expect = 1e-27 Identities = 71/187 (37%), Positives = 100/187 (53%) Frame = +2 Query: 14 RLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSVGLIH 193 +L TFQ LY +E GG+L I + G+ E A FYAAEI L +LH+ G+I+ Sbjct: 419 QLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIGLFFLHNQGIIY 478 Query: 194 RDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPEVLNS 373 RD+K +N++L ++GHIKI DFG K V P ST TF GT Y+ PE++ Sbjct: 479 RDLKLDNVMLDAEGHIKITDFGMCKE------NVFPGSTTR---TFCGTPDYIAPEIIAY 529 Query: 374 APATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDLIDKL 553 P D W+ G L++ML+G PF E +FQ I+ + + +P+ S EA + Sbjct: 530 QPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSREAVAICKGF 589 Query: 554 LDVDPTK 574 L P K Sbjct: 590 LTKHPGK 596
>KPCG_MOUSE (P63318) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 121 bits (304), Expect = 1e-27 Identities = 71/187 (37%), Positives = 100/187 (53%) Frame = +2 Query: 14 RLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSVGLIH 193 +L TFQ LY +E GG+L I + G+ E A FYAAEI L +LH+ G+I+ Sbjct: 419 QLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIGLFFLHNQGIIY 478 Query: 194 RDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPEVLNS 373 RD+K +N++L ++GHIKI DFG K V P ST TF GT Y+ PE++ Sbjct: 479 RDLKLDNVMLDAEGHIKITDFGMCKE------NVFPGSTTR---TFCGTPDYIAPEIIAY 529 Query: 374 APATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDLIDKL 553 P D W+ G L++ML+G PF E +FQ I+ + + +P+ S EA + Sbjct: 530 QPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSREAVAICKGF 589 Query: 554 LDVDPTK 574 L P K Sbjct: 590 LTKHPGK 596
>KCC1A_HUMAN (Q14012) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 370 Score = 121 bits (304), Expect = 1e-27 Identities = 71/198 (35%), Positives = 109/198 (55%), Gaps = 7/198 (3%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L ++ LY+ ++ GGELFD+IV KG +E +A +++D ++YLH + Sbjct: 76 PNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDL 135 Query: 182 GLIHRDVKPENLL---LTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYV 352 G++HRD+KPENLL L D I I+DFG K ++ P VL T GT YV Sbjct: 136 GIVHRDLKPENLLYYSLDEDSKIMISDFGLSK--MEDPGSVL--------STACGTPGYV 185 Query: 353 PPEVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFP----EFF 520 PEVL P + D W++G + +L G PF D ++ +F++I+ + F + Sbjct: 186 APEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDI 245 Query: 521 SDEARDLIDKLLDVDPTK 574 SD A+D I L++ DP K Sbjct: 246 SDSAKDFIRHLMEKDPEK 263
>AURKC_MOUSE (O88445) Serine/threonine-protein kinase 13 (EC 2.7.11.1)| (Aurora/Ipl1/Eg2 protein 1) (Aurora-C) Length = 282 Score = 121 bits (303), Expect = 2e-27 Identities = 68/189 (35%), Positives = 102/189 (53%) Frame = +2 Query: 8 VIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSVGL 187 ++RL+ F D +Y+ LE GGEL+ ++ R +L + E+ D L Y H + Sbjct: 76 ILRLYNYFYDDTRIYLILEYAPGGELYKELQRHQKLDQQRTATIIQELSDALTYCHEKKV 135 Query: 188 IHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPEVL 367 IHRD+KPENLLL +G +KI+DFG +V TP + R T GT Y+PPE++ Sbjct: 136 IHRDIKPENLLLGLNGEVKISDFGW---SVHTP--------SLRRKTMCGTLDYLPPEMI 184 Query: 368 NSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDLID 547 P DLW +G +++L G PF+ ++ ++RI D +FP A+DLI Sbjct: 185 AQKPYNEMVDLWCIGVLCYELLVGKPPFESSTSSETYRRIRQVDFKFPSSVPAGAQDLIS 244 Query: 548 KLLDVDPTK 574 KLL P++ Sbjct: 245 KLLRYHPSE 253
>KPCB_MOUSE (P68404) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 672 Score = 121 bits (303), Expect = 2e-27 Identities = 71/191 (37%), Positives = 102/191 (53%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + +L FQ LY +E GG+L I + GR E A FYAAEI L +L S Sbjct: 400 PFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSK 459 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+K +N++L S+GHIKIADFG K + + TF GT Y+ PE Sbjct: 460 GIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTK---------TFCGTPDYIAPE 510 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ P D WA G L++ML+G +PF+ E +FQ I+ ++ +P+ S EA + Sbjct: 511 IIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAI 570 Query: 542 IDKLLDVDPTK 574 L+ P K Sbjct: 571 CKGLMTKHPGK 581
>KPCB_BOVIN (P05126) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 672 Score = 121 bits (303), Expect = 2e-27 Identities = 71/191 (37%), Positives = 102/191 (53%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + +L FQ LY +E GG+L I + GR E A FYAAEI L +L S Sbjct: 400 PFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSK 459 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+K +N++L S+GHIKIADFG K + + TF GT Y+ PE Sbjct: 460 GIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTK---------TFCGTPDYIAPE 510 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ P D WA G L++ML+G +PF+ E +FQ I+ ++ +P+ S EA + Sbjct: 511 IIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAI 570 Query: 542 IDKLLDVDPTK 574 L+ P K Sbjct: 571 CKGLITKHPGK 581
>KPCB_RAT (P68403) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 670 Score = 121 bits (303), Expect = 2e-27 Identities = 71/191 (37%), Positives = 102/191 (53%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + +L FQ LY +E GG+L I + GR E A FYAAEI L +L S Sbjct: 400 PFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSK 459 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+K +N++L S+GHIKIADFG K + + TF GT Y+ PE Sbjct: 460 GIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTK---------TFCGTPDYIAPE 510 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ P D WA G L++ML+G +PF+ E +FQ I+ ++ +P+ S EA + Sbjct: 511 IIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAI 570 Query: 542 IDKLLDVDPTK 574 L+ P K Sbjct: 571 CKGLMTKHPGK 581
>KPCB_RABIT (P05772) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 670 Score = 121 bits (303), Expect = 2e-27 Identities = 71/191 (37%), Positives = 102/191 (53%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + +L FQ LY +E GG+L I + GR E A FYAAEI L +L S Sbjct: 400 PFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSK 459 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+K +N++L S+GHIKIADFG K + + TF GT Y+ PE Sbjct: 460 GIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTK---------TFCGTPDYIAPE 510 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ P D WA G L++ML+G +PF+ E +FQ I+ ++ +P+ S EA + Sbjct: 511 IIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAI 570 Query: 542 IDKLLDVDPTK 574 L+ P K Sbjct: 571 CKGLMTKHPGK 581
>KPCB_HUMAN (P05771) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 670 Score = 121 bits (303), Expect = 2e-27 Identities = 71/191 (37%), Positives = 102/191 (53%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + +L FQ LY +E GG+L I + GR E A FYAAEI L +L S Sbjct: 400 PFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSK 459 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+K +N++L S+GHIKIADFG K + + TF GT Y+ PE Sbjct: 460 GIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTK---------TFCGTPDYIAPE 510 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ P D WA G L++ML+G +PF+ E +FQ I+ ++ +P+ S EA + Sbjct: 511 IIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAI 570 Query: 542 IDKLLDVDPTK 574 L+ P K Sbjct: 571 CKGLMTKHPGK 581
>KBN8_YEAST (P38070) Probable serine/threonine-protein kinase YBR028C (EC| 2.7.11.1) Length = 525 Score = 120 bits (302), Expect = 2e-27 Identities = 65/194 (33%), Positives = 105/194 (54%), Gaps = 3/194 (1%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +++LF++F D+ LY+ L+ GGELF + G L E FYAAEI L +LH+ Sbjct: 212 PNIVKLFYSFHDNSKLYLLLQYIPGGELFYHLKEHGTLDETTVSFYAAEISCALRFLHTK 271 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFG-SVKPTVDTPIKVLPNSTNERACTFVGTAAYVPP 358 G+++RD+KPEN LL GH+ + DFG S K D+ + + +GT Y P Sbjct: 272 GVVYRDLKPENCLLNQRGHLVLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAP 331 Query: 359 EVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRI--IARDLRFPEFFSDEA 532 E+L + D ++LGC L+ ML G P+ ++ +I +I + + P + S+ Sbjct: 332 EILLGKAYSQNCDWYSLGCLLYDMLVGKPPYTGSNHKVIINKIQQNKQGPKIPFYLSEGM 391 Query: 533 RDLIDKLLDVDPTK 574 +D+++ LL + K Sbjct: 392 KDILNALLKKETAK 405
>CDS1_SCHPO (Q09170) Serine/threonine-protein kinase cds1 (EC 2.7.11.1)| (Checkpoint kinase cds1) Length = 460 Score = 120 bits (302), Expect = 2e-27 Identities = 67/201 (33%), Positives = 110/201 (54%), Gaps = 10/201 (4%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 PGV++ F++ L++ +E EGG+L D ++ G + E + + ++++ L +LH Sbjct: 229 PGVVQCHEIFENDDELFIVMEYVEGGDLMDFLIANGSIDEQDCKPLLKQLLETLLHLHKQ 288 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+ HRD+KPEN+L+T+D H+KI+DFG K + + T TF GT Y+ PE Sbjct: 289 GVTHRDIKPENILITNDFHLKISDFGLAK---------VIHGTGTFLETFCGTMGYLAPE 339 Query: 362 VLNSAPATFGN------DLWALGCTLFQMLSGSSPFKDASE----WLIFQRIIARDLRFP 511 VL S D+W+LGC L+ ML+ S PF +S+ LI + + Sbjct: 340 VLKSKNVNLDGGYDDKVDIWSLGCVLYVMLTASIPFASSSQAKCIELISKGAYPIEPLLE 399 Query: 512 EFFSDEARDLIDKLLDVDPTK 574 S+E DLI+++L+++P K Sbjct: 400 NEISEEGIDLINRMLEINPEK 420
>ICL1_KLULA (Q6CWQ4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 361 Score = 120 bits (301), Expect = 3e-27 Identities = 63/187 (33%), Positives = 108/187 (57%) Frame = +2 Query: 14 RLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSVGLIH 193 +L+ F D +Y+ +E GEL+ + G L+E A ++ ++ + L+Y+HS ++H Sbjct: 162 QLYGFFYDEKRVYLLMEYVYYGELYKFLKNNGPLNETLASYFVYQMANALDYMHSKNILH 221 Query: 194 RDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPEVLNS 373 RD+KPEN+L+ + IK+ DFG + N ++ T GT Y+ PE++ S Sbjct: 222 RDIKPENILIGFNNTIKLTDFGWS----------VYNEDGQKRKTLCGTIDYLSPELIKS 271 Query: 374 APATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDLIDKL 553 D+WALG +++L GS PF++ ++ + ++RI+ DL+FP S +ARDLI +L Sbjct: 272 REYNNKVDVWALGVLTYELLVGSPPFEEDTKEMTYRRILRCDLKFPLNVSPQARDLIVRL 331 Query: 554 LDVDPTK 574 L +P+K Sbjct: 332 LQFEPSK 338
>KPCG_RABIT (P10829) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| (PKC-delta) Length = 697 Score = 120 bits (301), Expect = 3e-27 Identities = 70/187 (37%), Positives = 100/187 (53%) Frame = +2 Query: 14 RLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSVGLIH 193 +L TFQ LY +E GG+L I + G+ E A FYAAEI L +LH+ G+I+ Sbjct: 419 QLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIGLFFLHNQGIIY 478 Query: 194 RDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPEVLNS 373 RD+K +N++L ++GHIKI DFG K V P +T TF GT Y+ PE++ Sbjct: 479 RDLKLDNVMLDAEGHIKITDFGMCKE------NVFPGTTTR---TFCGTPDYIAPEIIAY 529 Query: 374 APATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDLIDKL 553 P D W+ G L++ML+G PF E +FQ I+ + + +P+ S EA + Sbjct: 530 QPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSREAVAICKGF 589 Query: 554 LDVDPTK 574 L P K Sbjct: 590 LTKHPGK 596
>KPCG_HUMAN (P05129) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 120 bits (301), Expect = 3e-27 Identities = 70/187 (37%), Positives = 100/187 (53%) Frame = +2 Query: 14 RLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSVGLIH 193 +L TFQ LY +E GG+L I + G+ E A FYAAEI L +LH+ G+I+ Sbjct: 419 QLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIGLFFLHNQGIIY 478 Query: 194 RDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPEVLNS 373 RD+K +N++L ++GHIKI DFG K V P +T TF GT Y+ PE++ Sbjct: 479 RDLKLDNVMLDAEGHIKITDFGMCKE------NVFPGTTTR---TFCGTPDYIAPEIIAY 529 Query: 374 APATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDLIDKL 553 P D W+ G L++ML+G PF E +FQ I+ + + +P+ S EA + Sbjct: 530 QPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSREAVAICKGF 589 Query: 554 LDVDPTK 574 L P K Sbjct: 590 LTKHPGK 596
>PHOT1_ARATH (O48963) Phototropin-1 (EC 2.7.11.1) (Non-phototropic hypocotyl| protein 1) (Root phototropism protein 1) Length = 996 Score = 120 bits (301), Expect = 3e-27 Identities = 73/215 (33%), Positives = 115/215 (53%), Gaps = 24/215 (11%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGR--LSEDEARFYAAEIVDILEYLH 175 P + L+ +FQ + + + GGELF + R+ R L ED RFYAA++V LEYLH Sbjct: 721 PFLPALYASFQTKTHICLITDYYPGGELFMLLDRQPRKVLKEDAVRFYAAQVVVALEYLH 780 Query: 176 SVGLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNER------------ 319 G+I+RD+KPEN+L+ +G I ++DF T P ++P+ ++ Sbjct: 781 CQGIIYRDLKPENVLIQGNGDISLSDFDLSCLTSCKPQLLIPSIDEKKKKKQQKSQQTPI 840 Query: 320 --------ACTFVGTAAYVPPEVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLI 475 + +FVGT Y+ PE+++ A T D WALG +++ML G +PF+ + Sbjct: 841 FMAEPMRASNSFVGTEEYIAPEIISGAGHTSAVDWWALGILMYEMLYGYTPFRGKTRQKT 900 Query: 476 FQRIIARDLRFPEFF--SDEARDLIDKLLDVDPTK 574 F ++ +DL+FP S + + LI +LL DP K Sbjct: 901 FTNVLQKDLKFPASIPASLQVKQLIFRLLQRDPKK 935
>IPL1_CANAL (Q59S66) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 530 Score = 120 bits (301), Expect = 3e-27 Identities = 66/201 (32%), Positives = 108/201 (53%), Gaps = 12/201 (5%) Frame = +2 Query: 8 VIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSVGL 187 + RL+ F DS ++Y+ LE GEL+ + + R A Y +I L +LH G+ Sbjct: 304 ITRLYSWFHDSINIYLLLEYSIEGELYTHLKKLKRFDNIMASNYIFQITQALIFLHQRGI 363 Query: 188 IHRDVKPENLLLTSDGHIKIADFG-SVKPTVDTPIKVLPNST-----------NERACTF 331 IHRD+KPEN++++ D +K++DFG SV+ + + N T ++ T Sbjct: 364 IHRDLKPENIMISLDNQLKLSDFGWSVQINQNQNQNQIHNQTQTQKTPHQKKQKQKRLTI 423 Query: 332 VGTAAYVPPEVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFP 511 GT Y+PPE++ S F D+WALG +++L G PF+ + + +++I D+++P Sbjct: 424 CGTLDYLPPEMIESKSHDFSVDIWALGILCYELLVGKPPFEAINRNITYEKIAKVDIKYP 483 Query: 512 EFFSDEARDLIDKLLDVDPTK 574 +A DLI KL+ DP K Sbjct: 484 SNLDVDAIDLISKLVVKDPNK 504
>CIPK1_ARATH (Q8RWC9) CBL-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (SOS2-like protein kinase PKS13) (SNF1-related kinase 3.16) Length = 444 Score = 120 bits (301), Expect = 3e-27 Identities = 69/192 (35%), Positives = 104/192 (54%), Gaps = 3/192 (1%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++RL + M +E GGELFD+IV G+L+E + R +++D + Y HS Sbjct: 78 PHIVRLHEVLASKTKINMVMELVTGGELFDRIVSNGKLTETDGRKMFQQLIDGISYCHSK 137 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERAC--TFVGTAAYVP 355 G+ HRD+K EN+LL + GHIKI DFG + LP + T G+ YV Sbjct: 138 GVFHRDLKLENVLLDAKGHIKITDFG---------LSALPQHFRDDGLLHTTCGSPNYVA 188 Query: 356 PEVL-NSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEA 532 PEVL N +D+W+ G L+ +L+G PF D + +++Q+I D P + S A Sbjct: 189 PEVLANRGYDGAASDIWSCGVILYVILTGCLPFDDRNLAVLYQKICKGDPPIPRWLSPGA 248 Query: 533 RDLIDKLLDVDP 568 R +I ++LD +P Sbjct: 249 RTMIKRMLDPNP 260
>KPC1_DROME (P05130) Protein kinase C, brain isozyme (EC 2.7.11.13) (PKC)| (dPKC53E(BR)) Length = 679 Score = 120 bits (300), Expect = 4e-27 Identities = 69/191 (36%), Positives = 103/191 (53%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +++L FQ L+ +E GG+L QI + G+ E A FYAAEI L +LH+ Sbjct: 409 PFLVQLHSCFQTMDRLFFVMEYVNGGDLMFQIQQFGKFKEPVAVFYAAEIAAGLFFLHTK 468 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+++RD+K +N+LL +DGH+KIADFG K ++ + T + TF GT Y+ PE Sbjct: 469 GILYRDLKLDNVLLDADGHVKIADFGMCKE------NIVGDKTTK---TFCGTPDYIAPE 519 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ P D WA G L++ML G PF E +F I ++ +P+ S EA++ Sbjct: 520 IILYQPYGKSVDWWAYGVLLYEMLVGQPPFDGEDEEELFAAITDHNVSYPKSLSKEAKEA 579 Query: 542 IDKLLDVDPTK 574 L P K Sbjct: 580 CKGFLTKQPNK 590
>KPCI_BRARE (Q90XF2) Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota)| (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (Heart and soul protein) Length = 588 Score = 120 bits (300), Expect = 4e-27 Identities = 70/195 (35%), Positives = 104/195 (53%), Gaps = 9/195 (4%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L FQ L+ +E GG+L + R+ +L E+ ARFY+AEI L YLH Sbjct: 305 PFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHER 364 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+K +N+LL S+GHIK+ D+G K + P T TF GT Y+ PE Sbjct: 365 GIIYRDLKLDNVLLDSEGHIKLTDYGMCKE------GLRPGDTTS---TFCGTPNYIAPE 415 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPF---------KDASEWLIFQRIIARDLRFPE 514 +L F D WALG +F+M++G SPF +E +FQ I+ + +R P Sbjct: 416 ILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPR 475 Query: 515 FFSDEARDLIDKLLD 559 S +A ++ L+ Sbjct: 476 SLSVKAASVLKGFLN 490
>STK6_MOUSE (P97477) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Aurora-family kinase 1) (Aurora/IPL1-related kinase 1) (Ipl1- and aurora-related kinase 1) (Aurora-A) (Serine/threonine-protein kinase Ayk1) Length = 395 Score = 120 bits (300), Expect = 4e-27 Identities = 66/185 (35%), Positives = 101/185 (54%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++RL+ F D+ +Y+ LE G ++ ++ + + E Y E+ + L Y HS Sbjct: 182 PNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSK 241 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +IHRD+KPENLLL S+G +KIADFG +V P + R T GT Y+PPE Sbjct: 242 RVIHRDIKPENLLLGSNGELKIADFGW---SVHAP--------SSRRTTMCGTLDYLPPE 290 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ DLW+LG ++ L G PF+ + ++RI + FP+F ++ ARDL Sbjct: 291 MIEGRMHDEKVDLWSLGVLCYEFLVGMPPFEAHTYQETYRRISRVEFTFPDFVTEGARDL 350 Query: 542 IDKLL 556 I +LL Sbjct: 351 ISRLL 355
>AURKB_RAT (O55099) Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-| and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora-B) Length = 343 Score = 120 bits (300), Expect = 4e-27 Identities = 67/191 (35%), Positives = 101/191 (52%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +++L+ F D +Y+ LE GEL+ ++ + G E E+ D L Y H Sbjct: 138 PNILQLYNYFYDQQRIYLILEYAPRGELYKELQKSGTFDEQRTATIMEELSDALMYCHKK 197 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +IHRD+KPENLLL G +KIADFG +V P + R T GT Y+PPE Sbjct: 198 KVIHRDIKPENLLLGLQGELKIADFGW---SVHAP--------SLRRKTMCGTLDYLPPE 246 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ DLW +G ++++ G+ PF+ S ++RI+ DL+FP A+DL Sbjct: 247 MIEGRMHNEMVDLWCIGVLCYELMVGNPPFESPSHSETYRRIVKVDLKFPSSMPLGAKDL 306 Query: 542 IDKLLDVDPTK 574 I KLL +P++ Sbjct: 307 ISKLLKHNPSQ 317
>KDC1_DROME (P16911) Protein kinase DC1 (EC 2.7.11.1)| Length = 376 Score = 120 bits (300), Expect = 4e-27 Identities = 64/178 (35%), Positives = 97/178 (54%), Gaps = 2/178 (1%) Frame = +2 Query: 47 LYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSVGLIHRDVKPENLLLT 226 LY+ L GGELF R + +E ARFYAA++ LEY+H + L++RD+KPEN+LL Sbjct: 118 LYLILPLVNGGELFSYHRRVRKFNEKHARFYAAQVALALEYMHKMHLMYRDLKPENILLD 177 Query: 227 SDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPEVLNSAPATFGNDLWA 406 G+IKI DFG K + R T GT Y+ PE++ P D WA Sbjct: 178 QRGYIKITDFGFTK------------RVDGRTSTLCGTPEYLAPEIVQLRPYNKSVDWWA 225 Query: 407 LGCTLFQMLSGSSPF--KDASEWLIFQRIIARDLRFPEFFSDEARDLIDKLLDVDPTK 574 G +++ ++G SPF + L++ +I D + P +F+ + R L++ L+ VD +K Sbjct: 226 FGILVYEFVAGRSPFAIHNRDVILMYSKICICDYKMPSYFTSQLRSLVESLMQVDTSK 283
>AURKB_HUMAN (Q96GD4) Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-| and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (Aurora-related kinase 2) (STK-1) (Aurora-B) Length = 344 Score = 120 bits (300), Expect = 4e-27 Identities = 69/191 (36%), Positives = 101/191 (52%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++RL+ F D +Y+ LE GEL+ ++ + E E+ D L Y H Sbjct: 135 PNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGK 194 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +IHRD+KPENLLL G +KIADFG +V P + R T GT Y+PPE Sbjct: 195 KVIHRDIKPENLLLGLKGELKIADFGW---SVHAP--------SLRRKTMCGTLDYLPPE 243 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ DLW +G +++L G+ PF+ AS ++RI+ DL+FP A+DL Sbjct: 244 MIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPTGAQDL 303 Query: 542 IDKLLDVDPTK 574 I KLL +P++ Sbjct: 304 ISKLLRHNPSE 314
>PCK1_SCHPO (P36582) Protein kinase C-like 1 (EC 2.7.11.13)| Length = 988 Score = 120 bits (300), Expect = 4e-27 Identities = 73/191 (38%), Positives = 106/191 (55%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ LF +FQ S +Y +E GG+L I R+ + S ARFY AE+ L+Y H Sbjct: 725 PFLLNLFASFQTSTRVYFVMEYILGGDLMVHIQRQ-QFSVKRARFYGAEVCLALKYFHEN 783 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+ +RD+K +N+LL DGHI+IAD+G K + +L N+T+ TF GT ++ PE Sbjct: 784 GIAYRDLKLDNILLCPDGHIRIADYGLCKENM-----LLGNTTS----TFCGTPEFMAPE 834 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 +L + D WA G ++QML G SPFK E IF I++ + FP +A L Sbjct: 835 ILLEQQYSKDVDWWAFGVLMYQMLLGQSPFKGEDEEEIFDAILSDEPLFPINMPADAVSL 894 Query: 542 IDKLLDVDPTK 574 + LL DP + Sbjct: 895 LRGLLTRDPNQ 905
>GIN4_YEAST (Q12263) Serine/threonine-protein kinase GIN4 (EC 2.7.11.1)| Length = 1142 Score = 119 bits (299), Expect = 5e-27 Identities = 73/196 (37%), Positives = 115/196 (58%), Gaps = 5/196 (2%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P V+RL+ ++ + LY+ LE E GELF+ +V +G L E EA + +I+ + Y H++ Sbjct: 91 PNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAIRFFRQIIIGVSYCHAL 150 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G++HRD+KPENLLL +IKIADFG ++T K+L E +C G+ Y PE Sbjct: 151 GIVHRDLKPENLLLDHKYNIKIADFGMA--ALETEGKLL-----ETSC---GSPHYAAPE 200 Query: 362 VLNSAP-ATFGNDLWALGCTLFQMLSGSSPF--KDASEWLIFQRIIARDLRFP--EFFSD 526 +++ P F +D+W+ G LF +L+G PF +D + + ++ + P + S Sbjct: 201 IVSGIPYQGFASDVWSCGVILFALLTGRLPFDEEDGNIRTLLLKVQKGEFEMPSDDEISR 260 Query: 527 EARDLIDKLLDVDPTK 574 EA+DLI K+L VDP + Sbjct: 261 EAQDLIRKILTVDPER 276
>PLK4_HUMAN (O00444) Serine/threonine-protein kinase PLK4 (EC 2.7.11.21)| (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine-protein kinase 18) Length = 970 Score = 119 bits (299), Expect = 5e-27 Identities = 67/190 (35%), Positives = 107/190 (56%), Gaps = 1/190 (0%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGR-LSEDEARFYAAEIVDILEYLHS 178 P ++ L+ F+DS +Y+ LE C GE+ + + + SE+EAR + +I+ + YLHS Sbjct: 70 PSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHS 129 Query: 179 VGLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPP 358 G++HRD+ NLLLT + +IKIADFG + T +K+ +E+ T GT Y+ P Sbjct: 130 HGILHRDLTLSNLLLTRNMNIKIADFG-----LATQLKM----PHEKHYTLCGTPNYISP 180 Query: 359 EVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARD 538 E+ + +D+W+LGC + +L G PF + +++ D P F S EA+D Sbjct: 181 EIATRSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPTFLSIEAKD 240 Query: 539 LIDKLLDVDP 568 LI +LL +P Sbjct: 241 LIHQLLRRNP 250
>CPK15_ARATH (P92937) CBL-interacting serine/threonine-protein kinase 15 (EC| 2.7.11.1) (Serine/threonine-protein kinase ATPK10) (SOS2-like protein kinase PKS3) (SOS-interacting protein 2) (SNF1-related kinase 3.1) Length = 421 Score = 119 bits (299), Expect = 5e-27 Identities = 67/192 (34%), Positives = 112/192 (58%), Gaps = 3/192 (1%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L +Y +E +GGELF++ V G+L ED AR Y ++V +++ HS Sbjct: 70 PNIVELHEVMATKSKIYFVMEHVKGGELFNK-VSTGKLREDVARKYFQQLVRAVDFCHSR 128 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERAC--TFVGTAAYVP 355 G+ HRD+KPENLLL G++KI+DFG + L +S + T GT AYV Sbjct: 129 GVCHRDLKPENLLLDEHGNLKISDFG---------LSALSDSRRQDGLLHTTCGTPAYVA 179 Query: 356 PEVLN-SAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEA 532 PEV++ + F D+W+ G LF +L+G PF+D++ ++++I +++FP + + A Sbjct: 180 PEVISRNGYDGFKADVWSCGVILFVLLAGYLPFRDSNLMELYKKIGKAEVKFPNWLAPGA 239 Query: 533 RDLIDKLLDVDP 568 + L+ ++LD +P Sbjct: 240 KRLLKRILDPNP 251
>KS6A4_MOUSE (Q9Z2B9) Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (RSK-like protein kinase) (RLSK) Length = 773 Score = 119 bits (299), Expect = 5e-27 Identities = 72/197 (36%), Positives = 109/197 (55%), Gaps = 6/197 (3%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L + FQ L++ L+ GGE+F + ++ E E R Y EIV LE+LH + Sbjct: 96 PFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYGGEIVLALEHLHKL 155 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+K EN+LL S+GHI + DFG K + ER +F GT Y+ PE Sbjct: 156 GIIYRDLKLENVLLDSEGHIVLTDFGLSKEFL--------TEEKERTFSFCGTIEYMAPE 207 Query: 362 VLNSAPATFGN--DLWALGCTLFQMLSGSSPF----KDASEWLIFQRIIARDLRFPEFFS 523 ++ S A G D W+LG LF++L+G+SPF + ++ + +RI+ FP Sbjct: 208 IIRS-KAGHGKAVDWWSLGILLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFPLRIG 266 Query: 524 DEARDLIDKLLDVDPTK 574 A+DL+ +LL DP K Sbjct: 267 PVAQDLLQRLLCKDPKK 283 Score = 96.7 bits (239), Expect = 4e-20 Identities = 69/206 (33%), Positives = 95/206 (46%), Gaps = 15/206 (7%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHS- 178 P V+ L D Y+ LE GGEL + I +K SE EA +V + ++H Sbjct: 464 PNVVNLHEVLHDQLHTYLVLELLRGGELLEHIRKKRLFSESEASQILRSLVSAVSFMHEE 523 Query: 179 VGLIHRDVKPENLLLTSD---GHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAY 349 G++HRD+KPEN+L D +KI DFG + + P S E T T Y Sbjct: 524 AGVVHRDLKPENILYADDTPGAPVKIIDFGFAR--------LRPQSPAEPMQTPCFTLQY 575 Query: 350 VPPEVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDAS-----------EWLIFQRIIAR 496 PE+L DLW+LG L+ MLSG PF+ AS I + + Sbjct: 576 AAPELLAQQGYDESCDLWSLGVILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREGRFSL 635 Query: 497 DLRFPEFFSDEARDLIDKLLDVDPTK 574 D + S+EA++L+ LL VDP K Sbjct: 636 DGEAWQGVSEEAKELVRGLLTVDPAK 661
>KS6A1_MOUSE (P18653) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 724 Score = 119 bits (298), Expect = 6e-27 Identities = 68/189 (35%), Positives = 106/189 (56%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P V++L + FQ LY+ L+ GG+LF ++ ++ +E++ +FY AE+ L++LHS+ Sbjct: 122 PFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSL 181 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+KPEN+LL +GHIK+ DFG K +D ++A +F GT Y+ PE Sbjct: 182 GIIYRDLKPENILLDEEGHIKLTDFGLSKEAID---------HEKKAYSFCGTVEYMAPE 232 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 V+N T D W+ G +L G KD E + I+ L P+F S EA+ L Sbjct: 233 VVNRQGHTHSADWWSYG-----VLMG----KDRKETMTL--ILKAKLGMPQFLSTEAQSL 281 Query: 542 IDKLLDVDP 568 + L +P Sbjct: 282 LRALFKRNP 290 Score = 101 bits (252), Expect = 1e-21 Identities = 69/200 (34%), Positives = 98/200 (49%), Gaps = 11/200 (5%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +I L + D +Y+ E GGEL D+I+R+ SE EA F I +EYLHS Sbjct: 459 PNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTISKTVEYLHSQ 518 Query: 182 GLIHRDVKPENLLLTSDGH----IKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAY 349 G++HRD+KP N+L + ++I DFG K + N T TA + Sbjct: 519 GVVHRDLKPSNILYVDESGNPECLRICDFGFAKQL---------RAENGLLMTPCYTANF 569 Query: 350 VPPEVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDA---SEWLIFQRIIARDLRFP--- 511 V PEVL G D+W+LG L+ ML+G +PF + + I RI + Sbjct: 570 VAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTLSGGN 629 Query: 512 -EFFSDEARDLIDKLLDVDP 568 S+ A+DL+ K+L VDP Sbjct: 630 WNTVSETAKDLVSKMLHVDP 649
>KPC1B_CAEEL (P34885) Protein kinase C-like 1B (EC 2.7.11.13) (PKC1B)| Length = 707 Score = 119 bits (298), Expect = 6e-27 Identities = 63/181 (34%), Positives = 102/181 (56%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + L +FQ S L+ +E GG+L QI R + E ARFYAAE+ L++LH Sbjct: 437 PFLTALHSSFQTSDRLFFVMEYVNGGDLMFQIQRARKFDESRARFYAAEVTCALQFLHRN 496 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +I+RD+K +N+LL ++GH ++ADFG K + + + TF GT Y+ PE Sbjct: 497 DVIYRDLKLDNILLDAEGHCRLADFGMCKEGI---------NKDNLTSTFCGTPDYIAPE 547 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 +L D WALG +++M++G PF+ +E +F+ I+ D+ +P + S EA ++ Sbjct: 548 ILQEMEYGVSVDWWALGVLMYEMMAGQPPFEADNEDDLFEAILNDDVLYPVWLSKEAVNI 607 Query: 542 I 544 + Sbjct: 608 L 608
>KPCA_RAT (P05696) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 119 bits (298), Expect = 6e-27 Identities = 70/191 (36%), Positives = 101/191 (52%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + +L FQ LY +E GG+L I + G+ E +A FYAAEI L +LH Sbjct: 397 PFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKR 456 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+K +N++L S+GHIKIADFG K + + TF GT Y+ PE Sbjct: 457 GIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTR---------TFCGTPDYIAPE 507 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ P D WA G L++ML+G PF E +FQ I+ ++ +P+ S EA + Sbjct: 508 IIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSI 567 Query: 542 IDKLLDVDPTK 574 L+ P K Sbjct: 568 CKGLMTKHPAK 578
>KPCA_RABIT (P10102) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 119 bits (298), Expect = 6e-27 Identities = 70/191 (36%), Positives = 101/191 (52%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + +L FQ LY +E GG+L I + G+ E +A FYAAEI L +LH Sbjct: 397 PFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKR 456 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+K +N++L S+GHIKIADFG K + + TF GT Y+ PE Sbjct: 457 GIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTR---------TFCGTPDYIAPE 507 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ P D WA G L++ML+G PF E +FQ I+ ++ +P+ S EA + Sbjct: 508 IIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSI 567 Query: 542 IDKLLDVDPTK 574 L+ P K Sbjct: 568 CKGLMTKHPAK 578
>KPCA_MOUSE (P20444) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 119 bits (298), Expect = 6e-27 Identities = 70/191 (36%), Positives = 100/191 (52%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + +L FQ LY +E GG+L I + G+ E +A FYAAEI L +LH Sbjct: 397 PFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKR 456 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+K N++L S+GHIKIADFG K + + TF GT Y+ PE Sbjct: 457 GIIYRDLKLNNVMLNSEGHIKIADFGMCKEHMMDGVTTR---------TFCGTPDYIAPE 507 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ P D WA G L++ML+G PF E +FQ I+ ++ +P+ S EA + Sbjct: 508 IIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSI 567 Query: 542 IDKLLDVDPTK 574 L+ P K Sbjct: 568 CKGLMTKQPAK 578
>KPCA_HUMAN (P17252) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 119 bits (298), Expect = 6e-27 Identities = 70/191 (36%), Positives = 101/191 (52%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + +L FQ LY +E GG+L I + G+ E +A FYAAEI L +LH Sbjct: 397 PFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKR 456 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+K +N++L S+GHIKIADFG K + + TF GT Y+ PE Sbjct: 457 GIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTR---------TFCGTPDYIAPE 507 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ P D WA G L++ML+G PF E +FQ I+ ++ +P+ S EA + Sbjct: 508 IIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSI 567 Query: 542 IDKLLDVDPTK 574 L+ P K Sbjct: 568 CKGLMTKHPAK 578
>CRK_DAUCA (P53681) CDPK-related protein kinase (EC 2.7.11.1) (PK421)| Length = 602 Score = 119 bits (298), Expect = 6e-27 Identities = 72/200 (36%), Positives = 116/200 (58%), Gaps = 11/200 (5%) Frame = +2 Query: 8 VIRLFFTFQDSYSLYMALESCEGGELFDQIV-RKGRLSEDEARFYAAEIVDILEYLHSVG 184 +++ + F+D ++Y+ +E CEGGEL D+I+ R G+ +ED+A+ +I++++ + H G Sbjct: 212 LVQFYDAFEDHTNVYVVMELCEGGELLDRILSRGGKYTEDDAKAVMIQILNVVAFCHLQG 271 Query: 185 LIHRDVKPENLLLTS---DGHIKIADFG---SVKPTVDTPIKVLPNSTNERACTFVGTAA 346 ++HRD+KPEN L S D +K DFG VKP +ER VG+A Sbjct: 272 VVHRDLKPENFLFKSKDEDSQLKAIDFGLSDYVKP-------------DERLNDIVGSAY 318 Query: 347 YVPPEVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPE---- 514 YV PEVL+ + +T D+W++G + +L GS PF +E IF+ ++ +L F E Sbjct: 319 YVAPEVLHRSYSTEA-DVWSIGVISYILLCGSRPFWARTESGIFRAVLKANLSFDEPPWP 377 Query: 515 FFSDEARDLIDKLLDVDPTK 574 S EA+D + +LL+ DP K Sbjct: 378 SVSSEAKDFVKRLLNKDPRK 397
>KS6A4_HUMAN (O75676) Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (Ribosomal protein kinase B) (RSKB) Length = 772 Score = 119 bits (298), Expect = 6e-27 Identities = 70/196 (35%), Positives = 107/196 (54%), Gaps = 5/196 (2%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L + FQ L++ L+ GGE+F + ++ E E R Y EIV LE+LH + Sbjct: 96 PFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYGGEIVLALEHLHKL 155 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+K EN+LL S+GHI + DFG K + ER +F GT Y+ PE Sbjct: 156 GIIYRDLKLENVLLDSEGHIVLTDFGLSKEFL--------TEEKERTFSFCGTIEYMAPE 207 Query: 362 VLNSAPA-TFGNDLWALGCTLFQMLSGSSPF----KDASEWLIFQRIIARDLRFPEFFSD 526 ++ S D W+LG LF++L+G+SPF + ++ + +RI+ FP Sbjct: 208 IIRSKTGHGKAVDWWSLGILLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFPPRIGP 267 Query: 527 EARDLIDKLLDVDPTK 574 A+DL+ +LL DP K Sbjct: 268 VAQDLLQRLLCKDPKK 283 Score = 95.1 bits (235), Expect = 1e-19 Identities = 68/206 (33%), Positives = 94/206 (45%), Gaps = 15/206 (7%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLH-S 178 P V+ L D Y+ LE GGEL + I +K SE EA +V + ++H Sbjct: 464 PNVVNLHEVHHDQLHTYLVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSFMHEE 523 Query: 179 VGLIHRDVKPENLLLTSD---GHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAY 349 G++HRD+KPEN+L D +KI DFG ++ P S T T Y Sbjct: 524 AGVVHRDLKPENILYADDTPGAPVKIIDFGFA--------RLRPQSPGVPMQTPCFTLQY 575 Query: 350 VPPEVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDAS-----------EWLIFQRIIAR 496 PE+L DLW+LG L+ MLSG PF+ AS I + + Sbjct: 576 AAPELLAQQGYDESCDLWSLGVILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREGRFSL 635 Query: 497 DLRFPEFFSDEARDLIDKLLDVDPTK 574 D + S+EA++L+ LL VDP K Sbjct: 636 DGEAWQGVSEEAKELVRGLLTVDPAK 661
>KPCE_RAT (P09216) Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon)| Length = 737 Score = 119 bits (298), Expect = 6e-27 Identities = 64/191 (33%), Positives = 103/191 (53%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + +L+ FQ L+ +E GG+L QI R + E + FYAAE+ L +LH Sbjct: 467 PYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSGFYAAEVTSALMFLHQH 526 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+K +N+LL ++GH K+ADFG K + + TF GT Y+ PE Sbjct: 527 GVIYRDLKLDNILLDAEGHSKLADFGMCKEGILNGV---------TTTTFCGTPDYIAPE 577 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 +L D WALG +++M++G PF+ +E +F+ I+ D+ +P + S EA + Sbjct: 578 ILQELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSI 637 Query: 542 IDKLLDVDPTK 574 + + +P K Sbjct: 638 LKAFMTKNPHK 648
>CCAMK_LILLO (Q43531) Calcium and calcium/calmodulin-dependent| serine/threonine-protein kinase (EC 2.7.11.17) (LlCCaMK) Length = 520 Score = 119 bits (297), Expect = 8e-27 Identities = 79/200 (39%), Positives = 104/200 (52%), Gaps = 9/200 (4%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P VI L ++D+ +++ LE C GGELFD+IV + R SE EA +I L LH Sbjct: 102 PNVIHLHDVYEDANGVHLVLELCSGGELFDRIVAQDRYSESEAAEVVQQIASGLAALHKS 161 Query: 182 GLIHRDVKPENLLLTSD---GHIKIADFG--SVKPTVDTPIKVLPNSTNERACTFVGTAA 346 +IHRD+KPEN L + +KI DFG SV+ D PI L G+ Sbjct: 162 TIIHRDLKPENCLFLNQEKRSTLKIMDFGLSSVEDFTD-PIVAL-----------FGSID 209 Query: 347 YVPPEVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEF--- 517 YV PE L+ + +D+W+LG L+ +LSG PF S QRI+A D F E Sbjct: 210 YVSPEALSQRQVSSASDMWSLGVILYILLSGCPPFHAPSNREKQQRILAGDFSFEEHTWK 269 Query: 518 -FSDEARDLIDKLLDVDPTK 574 + A+DLI LL VDP K Sbjct: 270 TITSSAKDLISSLLSVDPYK 289
>STK6_RAT (P59241) Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Aurora-A)| (ratAurA) Length = 397 Score = 119 bits (297), Expect = 8e-27 Identities = 66/185 (35%), Positives = 100/185 (54%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++RL+ F D+ +Y+ LE G ++ ++ + + E Y E+ + L Y HS Sbjct: 184 PNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSK 243 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +IHRD+KPENLLL S+G +KIADFG +V P + R T GT Y PPE Sbjct: 244 RVIHRDIKPENLLLGSNGELKIADFGW---SVHAP--------SSRRTTLCGTLDYQPPE 292 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ DLW+LG ++ L G PF+ + ++RI + FP+F ++ ARDL Sbjct: 293 MIEGRMHDEKVDLWSLGVLCYEFLVGMPPFEAHTYQETYRRISRVEFTFPDFVTEGARDL 352 Query: 542 IDKLL 556 I +LL Sbjct: 353 ISRLL 357
>KPC1_YEAST (P24583) Protein kinase C-like 1 (EC 2.7.11.13) (PKC 1)| Length = 1151 Score = 119 bits (297), Expect = 8e-27 Identities = 72/191 (37%), Positives = 100/191 (52%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + L+ +FQ +Y A+E GG+L V+ RLS A+FYAAE++ L+Y H Sbjct: 885 PFLTNLYCSFQTENRIYFAMEFIGGGDLMWH-VQNQRLSVRRAKFYAAEVLLALKYFHDN 943 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+K EN+LLT +GHIKIAD+G K + R TF GT ++ PE Sbjct: 944 GVIYRDLKLENILLTPEGHIKIADYGLCKDEM---------WYGNRTSTFCGTPEFMAPE 994 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 +L T D WA G L+QML SPF E +F I+ + +P + E + Sbjct: 995 ILKEQEYTKAVDWWAFGVLLYQMLLCQSPFSGDDEDEVFNAILTDEPLYPIDMAGEIVQI 1054 Query: 542 IDKLLDVDPTK 574 LL DP K Sbjct: 1055 FQGLLTKDPEK 1065
>KPCA_BOVIN (P04409) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 118 bits (296), Expect = 1e-26 Identities = 70/191 (36%), Positives = 101/191 (52%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + +L FQ LY +E GG+L I + G+ E +A FYAAEI L +LH Sbjct: 397 PFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKR 456 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+K +N++L S+GHIKIADFG K + + TF GT Y+ PE Sbjct: 457 GIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTR---------TFCGTPDYIAPE 507 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ P D WA G L++ML+G PF E +FQ I+ ++ +P+ S EA + Sbjct: 508 IIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSI 567 Query: 542 IDKLLDVDPTK 574 L+ P K Sbjct: 568 CKGLMTKHPGK 578
>BRSK1_HUMAN (Q8TDC3) BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1| kinase) (SAD1A) Length = 794 Score = 117 bits (294), Expect = 2e-26 Identities = 67/192 (34%), Positives = 104/192 (54%), Gaps = 1/192 (0%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P V++L +++ LY+ LE GGELFD +V+KGRL+ EAR + +IV L++ HS Sbjct: 107 PHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSY 166 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 + HRD+KPENLLL +I+IADFG V +S E +C G+ Y PE Sbjct: 167 SICHRDLKPENLLLDEKNNIRIADFGMASLQVG-------DSLLETSC---GSPHYACPE 216 Query: 362 VLNSAPATFGN-DLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARD 538 V+ D+W+ G LF +L G+ PF D + + +++ P F + + Sbjct: 217 VIKGEKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQS 276 Query: 539 LIDKLLDVDPTK 574 L+ +++V+P K Sbjct: 277 LLRGMIEVEPEK 288
>MARK1_MOUSE (Q8VHJ5) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) (ELKL motif serine/threonine-protein kinase 3) Length = 795 Score = 117 bits (294), Expect = 2e-26 Identities = 68/193 (35%), Positives = 106/193 (54%), Gaps = 2/193 (1%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +++LF + +LY+ +E GGE+FD +V GR+ E EAR +IV ++Y H Sbjct: 117 PNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQK 176 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFG-SVKPTVDTPIKVLPNSTNERACTFVGTAAYVPP 358 ++HRD+K ENLLL +D +IKIADFG S + TV + TF G+ Y P Sbjct: 177 CIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGNKLD-----------TFCGSPPYAAP 225 Query: 359 EVLNSAPATFGN-DLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEAR 535 E+ D+W+LG L+ ++SGS PF + + +R++ R P + S + Sbjct: 226 ELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRVPFYMSTDCE 285 Query: 536 DLIDKLLDVDPTK 574 +L+ KLL ++P K Sbjct: 286 NLLKKLLVLNPIK 298
>MARK1_HUMAN (Q9P0L2) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) Length = 795 Score = 117 bits (294), Expect = 2e-26 Identities = 68/193 (35%), Positives = 105/193 (54%), Gaps = 2/193 (1%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +++LF + +LY+ +E GGE+FD +V GR+ E EAR +IV ++Y H Sbjct: 117 PNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQK 176 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFG-SVKPTVDTPIKVLPNSTNERACTFVGTAAYVPP 358 ++HRD+K ENLLL D +IKIADFG S + TV + TF G+ Y P Sbjct: 177 YIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLD-----------TFCGSPPYAAP 225 Query: 359 EVLNSAPATFGN-DLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEAR 535 E+ D+W+LG L+ ++SGS PF + + +R++ R P + S + Sbjct: 226 ELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCE 285 Query: 536 DLIDKLLDVDPTK 574 +L+ KLL ++P K Sbjct: 286 NLLKKLLVLNPIK 298
>MARK1_RAT (O08678) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) Length = 793 Score = 117 bits (294), Expect = 2e-26 Identities = 68/193 (35%), Positives = 106/193 (54%), Gaps = 2/193 (1%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +++LF + +LY+ +E GGE+FD +V GR+ E EAR +IV ++Y H Sbjct: 117 PNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQK 176 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFG-SVKPTVDTPIKVLPNSTNERACTFVGTAAYVPP 358 ++HRD+K ENLLL +D +IKIADFG S + TV + TF G+ Y P Sbjct: 177 CIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGNKLD-----------TFCGSPPYAAP 225 Query: 359 EVLNSAPATFGN-DLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEAR 535 E+ D+W+LG L+ ++SGS PF + + +R++ R P + S + Sbjct: 226 ELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRVPFYMSTDCE 285 Query: 536 DLIDKLLDVDPTK 574 +L+ KLL ++P K Sbjct: 286 NLLKKLLVLNPIK 298
>PLK4_MOUSE (Q64702) Serine/threonine-protein kinase PLK4 (EC 2.7.11.21)| (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine-protein kinase 18) Length = 925 Score = 117 bits (294), Expect = 2e-26 Identities = 65/190 (34%), Positives = 103/190 (54%), Gaps = 1/190 (0%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGR-LSEDEARFYAAEIVDILEYLHS 178 P V+ L+ F+D+ +Y+ LE C GE+ + + + SE EAR + +I+ + YLHS Sbjct: 70 PSVLELYNYFEDNNYVYLVLEMCHNGEMNRYLKNRMKPFSEREARHFMHQIITGMLYLHS 129 Query: 179 VGLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPP 358 G++HRD+ N+LLT + +IKIADFG + N +E+ T GT Y+ P Sbjct: 130 HGILHRDLTLSNILLTRNMNIKIADFG---------LATQLNMPHEKHYTLCGTPNYISP 180 Query: 359 EVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARD 538 E+ + +D+W+LGC + +L G PF + +++ D P F S EA+D Sbjct: 181 EIATRSAHGLESDIWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPAFLSREAQD 240 Query: 539 LIDKLLDVDP 568 LI +LL +P Sbjct: 241 LIHQLLRRNP 250
>CDC5_YEAST (P32562) Cell cycle serine/threonine-protein kinase CDC5/MSD2 (EC| 2.7.11.21) Length = 705 Score = 117 bits (293), Expect = 2e-26 Identities = 69/193 (35%), Positives = 106/193 (54%), Gaps = 4/193 (2%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +++ F+D ++Y+ LE C G L + + R+ L+E E RF+ +I ++Y+HS Sbjct: 139 PNIVQFIDCFEDDSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSR 198 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +IHRD+K N+ S+ ++KI DFG VL N +ER T GT Y+ PE Sbjct: 199 RVIHRDLKLGNIFFDSNYNLKIGDFGLA--------AVLANE-SERKYTICGTPNYIAPE 249 Query: 362 VL--NSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFP--EFFSDE 529 VL + +F D+W+LG L+ +L G PF+ I++RI RD FP + SDE Sbjct: 250 VLMGKHSGHSFEVDIWSLGVMLYALLIGKPPFQARDVNTIYERIKCRDFSFPRDKPISDE 309 Query: 530 ARDLIDKLLDVDP 568 + LI +L +DP Sbjct: 310 GKILIRDILSLDP 322
>AURKB_MOUSE (O70126) Serine/threonine-protein kinase 12 (EC 2.7.11.1)| (Aurora-related kinase 2) (Serine/threonine-protein kinase 5) (STK-1) (Aurora-B) Length = 345 Score = 117 bits (293), Expect = 2e-26 Identities = 66/189 (34%), Positives = 98/189 (51%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +++L+ F D +Y+ LE GEL+ ++ + E E+ D L Y H Sbjct: 140 PNILQLYNYFYDQQRIYLILEYAPRGELYKELQKSRTFDEQRTATIMEELSDALTYCHKK 199 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +IHRD+KPENLLL G +KIADFG +V P + R T GT Y+PPE Sbjct: 200 KVIHRDIKPENLLLGLQGELKIADFGW---SVHAP--------SLRRKTMCGTLDYLPPE 248 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ DLW +G ++++ G+ PF+ S ++RI+ DL+FP A+DL Sbjct: 249 MIEGRMHNEMVDLWCIGVLCYELMVGNPPFESPSHSETYRRIVKVDLKFPSSVPSGAQDL 308 Query: 542 IDKLLDVDP 568 I KLL +P Sbjct: 309 ISKLLKHNP 317
>KCC1B_RAT (O70150) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase homolog) Length = 343 Score = 117 bits (293), Expect = 2e-26 Identities = 70/198 (35%), Positives = 104/198 (52%), Gaps = 7/198 (3%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L + LY+A+E GGELFD+I+ +G +E +A +++ + YLHS+ Sbjct: 71 PNIVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSL 130 Query: 182 GLIHRDVKPENLLLTS---DGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYV 352 G++HRD+KPENLL + D I ++DFG K+ + AC GT YV Sbjct: 131 GIVHRDLKPENLLYATPFEDSKIMVSDFGL--------SKIQAGNMLGTAC---GTPGYV 179 Query: 353 PPEVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFF---- 520 PE+L P D+WALG + +L G PF D S+ +F +I+ F F Sbjct: 180 APELLEQKPYGKAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDI 239 Query: 521 SDEARDLIDKLLDVDPTK 574 S+ A+D I LL+ DP K Sbjct: 240 SESAKDFIRHLLERDPQK 257
>KCC1B_MOUSE (Q9QYK9) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase homolog) Length = 343 Score = 117 bits (293), Expect = 2e-26 Identities = 70/198 (35%), Positives = 104/198 (52%), Gaps = 7/198 (3%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L + LY+A+E GGELFD+I+ +G +E +A +++ + YLHS+ Sbjct: 71 PNIVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSL 130 Query: 182 GLIHRDVKPENLLLTS---DGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYV 352 G++HRD+KPENLL + D I ++DFG K+ + AC GT YV Sbjct: 131 GIVHRDLKPENLLYATPFEDSKIMVSDFGL--------SKIQAGNMLGTAC---GTPGYV 179 Query: 353 PPEVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFF---- 520 PE+L P D+WALG + +L G PF D S+ +F +I+ F F Sbjct: 180 APELLEQKPYGKAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDI 239 Query: 521 SDEARDLIDKLLDVDPTK 574 S+ A+D I LL+ DP K Sbjct: 240 SESAKDFIRHLLERDPQK 257
>KCC1B_HUMAN (Q6P2M8) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase) Length = 343 Score = 117 bits (293), Expect = 2e-26 Identities = 70/198 (35%), Positives = 104/198 (52%), Gaps = 7/198 (3%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L + LY+A+E GGELFD+I+ +G +E +A +++ + YLHS+ Sbjct: 71 PNIVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSL 130 Query: 182 GLIHRDVKPENLLLTS---DGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYV 352 G++HRD+KPENLL + D I ++DFG K+ + AC GT YV Sbjct: 131 GIVHRDLKPENLLYATPFEDSKIMVSDFGL--------SKIQAGNMLGTAC---GTPGYV 179 Query: 353 PPEVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFF---- 520 PE+L P D+WALG + +L G PF D S+ +F +I+ F F Sbjct: 180 APELLEQKPYGKAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDI 239 Query: 521 SDEARDLIDKLLDVDPTK 574 S+ A+D I LL+ DP K Sbjct: 240 SESAKDFIRHLLERDPQK 257
>KCC2A_MOUSE (P11798) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 117 bits (292), Expect = 3e-26 Identities = 69/198 (34%), Positives = 107/198 (54%), Gaps = 7/198 (3%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++RL + + Y+ + GGELF+ IV + SE +A +I++ + + H + Sbjct: 70 PNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQM 129 Query: 182 GLIHRDVKPENLLLTS---DGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYV 352 G++HRD+KPENLLL S +K+ADFG + + +R F GT Y+ Sbjct: 130 GVVHRDLKPENLLLASKLKGAAVKLADFG---------LAIEVEGEQQRWFGFAGTPGYL 180 Query: 353 PPEVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFP----EFF 520 PEVL P DLWA G L+ +L G PF D + ++Q+I AR FP + Sbjct: 181 SPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKARAYDFPSPEWDTV 240 Query: 521 SDEARDLIDKLLDVDPTK 574 + EA+DLI+K+L ++P+K Sbjct: 241 TPEAKDLINKMLTINPSK 258
>RKIN1_SECCE (Q02723) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 502 Score = 117 bits (292), Expect = 3e-26 Identities = 68/192 (35%), Positives = 102/192 (53%), Gaps = 1/192 (0%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +IR++ +++ +E C+ G+L D I+ K RL EDEAR +I+ +EY H Sbjct: 75 PHIIRVYEVIVTPKDIFVVMEYCQNGDLLDYILEKRRLQEDEARRTFQQIISAVEYCHRN 134 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTP-IKVLPNSTNERACTFVGTAAYVPP 358 ++HRD+KPENLLL S ++K+ADFG D +K S N A + Y P Sbjct: 135 KVVHRDLKPENLLLDSKYNVKLADFGLSNVMHDGHFLKTSCGSLNYAAPEVISGKLYAGP 194 Query: 359 EVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARD 538 E+ D+W+ G L+ +L G+ PF D + +F++I P + SD RD Sbjct: 195 EI----------DVWSCGVILYALLCGAVPFDDDNIPNLFKKIKGGTYILPIYLSDLVRD 244 Query: 539 LIDKLLDVDPTK 574 LI ++L VDP K Sbjct: 245 LISRMLIVDPMK 256
>KAPL_APLCA (P21901) Spermatozoon-associated protein kinase (EC 2.7.11.1) (SAK)| (C-APL-B) Length = 351 Score = 116 bits (291), Expect = 4e-26 Identities = 64/191 (33%), Positives = 99/191 (51%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P V+R F+D+ +LYM +E GGELF + +KGRL E FYAA++ L+YLH+ Sbjct: 102 PFVVRCLNAFKDTTNLYMVMEFVNGGELFHLLRKKGRLPEYWCTFYAAQVTMALQYLHNC 161 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 L++RD+KPEN+LL G++K+ DFG T GT Y+ PE Sbjct: 162 SLLYRDLKPENILLDHLGYLKVTDFG------------FDRRVQGHTWTLCGTPQYLAPE 209 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 ++ + LG ++++ +G PF +++ I+ L FP FF RDL Sbjct: 210 MILNRSYASQWTTGGLGILIYELNAGFVPFDHKVPLKLYELIVECRLTFPSFFKPTLRDL 269 Query: 542 IDKLLDVDPTK 574 + ++ VD T+ Sbjct: 270 LTNIIQVDVTR 280
>AAPK1_CAEEL (P45894) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMP-activated kinase 1) Length = 589 Score = 116 bits (290), Expect = 5e-26 Identities = 70/192 (36%), Positives = 97/192 (50%), Gaps = 1/192 (0%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + RLF +++ +E GGELF I RKG L E+R Y +I+ + Y H+ Sbjct: 82 PHITRLFRVISTPSDIFLVMELVSGGELFSYITRKGALPIRESRRYFQQIISGVSYCHNH 141 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTP-IKVLPNSTNERACTFVGTAAYVPP 358 ++HRD+KPENLLL ++ +IKIADFG D + S N A + YV P Sbjct: 142 MIVHRDLKPENLLLDANKNIKIADFGLSNYMTDGDLLSTACGSPNYAAPELISNKLYVGP 201 Query: 359 EVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARD 538 EV DLW+ G L+ ML G+ PF D + +F +I + P +A D Sbjct: 202 EV----------DLWSCGVILYAMLCGTLPFDDQNVPTLFAKIKSGRYTVPYSMEKQAAD 251 Query: 539 LIDKLLDVDPTK 574 LI +L VDP K Sbjct: 252 LISTMLQVDPVK 263
>PKN2_MOUSE (Q8BWW9) Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein| kinase C-like 2) (Protein-kinase C-related kinase 2) Length = 983 Score = 116 bits (290), Expect = 5e-26 Identities = 69/191 (36%), Positives = 101/191 (52%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ LF FQ + +E GG+L I SE A FYAA +V L+YLH Sbjct: 717 PFLVNLFACFQTKEHVCFVMEYAAGGDLMMHI-HTDVFSEPRAVFYAACVVLGLQYLHEH 775 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +++RD+K +NLLL ++G +KIADFG K + +R TF GT ++ PE Sbjct: 776 KIVYRDLKLDNLLLDTEGFVKIADFGLCKEGM---------GYGDRTSTFCGTPEFLAPE 826 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 VL T D W LG +++ML G SPF E +F I+ ++R+P F S EA + Sbjct: 827 VLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISI 886 Query: 542 IDKLLDVDPTK 574 + +LL +P + Sbjct: 887 MRRLLRRNPER 897
>MARK3_MOUSE (Q03141) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| (MPK-10) (ELKL motif kinase 2) Length = 753 Score = 116 bits (290), Expect = 5e-26 Identities = 66/193 (34%), Positives = 106/193 (54%), Gaps = 2/193 (1%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +++LF + +LY+ +E GGE+FD +V GR+ E EAR +IV ++Y H Sbjct: 113 PNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQK 172 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFG-SVKPTVDTPIKVLPNSTNERACTFVGTAAYVPP 358 ++HRD+K ENLLL +D +IKIADFG S + TV + + TF G+ Y P Sbjct: 173 RIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGSKLD-----------TFCGSPPYAAP 221 Query: 359 EVLNSAPATFGN-DLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEAR 535 E+ D+W+LG L+ ++SGS PF + + +R++ R P + S + Sbjct: 222 ELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCE 281 Query: 536 DLIDKLLDVDPTK 574 +L+ + L ++P K Sbjct: 282 NLLKRFLVLNPVK 294
>PKN2_HUMAN (Q16513) Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein| kinase C-like 2) (Protein-kinase C-related kinase 2) Length = 984 Score = 116 bits (290), Expect = 5e-26 Identities = 69/191 (36%), Positives = 101/191 (52%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ LF FQ + +E GG+L I SE A FYAA +V L+YLH Sbjct: 718 PFLVNLFACFQTKEHVCFVMEYAAGGDLMMHI-HTDVFSEPRAVFYAACVVLGLQYLHEH 776 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +++RD+K +NLLL ++G +KIADFG K + +R TF GT ++ PE Sbjct: 777 KIVYRDLKLDNLLLDTEGFVKIADFGLCKEGM---------GYGDRTSTFCGTPEFLAPE 827 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 VL T D W LG +++ML G SPF E +F I+ ++R+P F S EA + Sbjct: 828 VLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISI 887 Query: 542 IDKLLDVDPTK 574 + +LL +P + Sbjct: 888 MRRLLRRNPER 898
>MARK2_RAT (O08679) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1) Length = 722 Score = 116 bits (290), Expect = 5e-26 Identities = 64/192 (33%), Positives = 103/192 (53%), Gaps = 1/192 (0%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +++LF + +LY+ +E GGE+FD +V GR+ E EAR +IV ++Y H Sbjct: 110 PNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQK 169 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 ++HRD+K ENLLL +D +IKIADFG + + TF G+ Y PE Sbjct: 170 FIVHRDLKAENLLLDADMNIKIADFGFSNEF----------TFGNKLDTFCGSPPYAAPE 219 Query: 362 VLNSAPATFGN-DLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARD 538 + D+W+LG L+ ++SGS PF + + +R++ R P + S + + Sbjct: 220 LFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCEN 279 Query: 539 LIDKLLDVDPTK 574 L+ K L ++P+K Sbjct: 280 LLKKFLILNPSK 291
>MARK2_HUMAN (Q7KZI7) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog) Length = 788 Score = 116 bits (290), Expect = 5e-26 Identities = 64/192 (33%), Positives = 103/192 (53%), Gaps = 1/192 (0%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +++LF + +LY+ +E GGE+FD +V GR+ E EAR +IV ++Y H Sbjct: 110 PNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQK 169 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 ++HRD+K ENLLL +D +IKIADFG + + TF G+ Y PE Sbjct: 170 FIVHRDLKAENLLLDADMNIKIADFGFSNEF----------TFGNKLDTFCGSPPYAAPE 219 Query: 362 VLNSAPATFGN-DLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARD 538 + D+W+LG L+ ++SGS PF + + +R++ R P + S + + Sbjct: 220 LFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCEN 279 Query: 539 LIDKLLDVDPTK 574 L+ K L ++P+K Sbjct: 280 LLKKFLILNPSK 291
>KPSH1_BRARE (Q501V0) Serine/threonine-protein kinase H1 homolog (EC 2.7.11.1)| Length = 422 Score = 115 bits (289), Expect = 7e-26 Identities = 69/196 (35%), Positives = 110/196 (56%), Gaps = 7/196 (3%) Frame = +2 Query: 8 VIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSVGL 187 +I+L F+ + +YM +E GGELFD+I+ +G +E +A ++D ++YLH++G+ Sbjct: 153 IIQLMEVFETAERVYMVMELATGGELFDRIITRGSFTERDATRVLQMVLDGVKYLHTLGI 212 Query: 188 IHRDVKPENLLL---TSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPP 358 HRD+KPENLL +D I I DFG + T + L +T GT Y+ P Sbjct: 213 THRDLKPENLLYYHPGADSKIMITDFG-LASTRKKGDECLMKTT-------CGTPEYIAP 264 Query: 359 EVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFP----EFFSD 526 E+L P T D+WALG + +LSG+ PF+D + ++++I+ F S+ Sbjct: 265 EILVRKPYTNAVDMWALGVISYILLSGTMPFEDDNRMRLYRQILKGKYSFSGEPWPSVSN 324 Query: 527 EARDLIDKLLDVDPTK 574 A+D ID++L VDP + Sbjct: 325 LAKDFIDRVLTVDPNE 340
>KGP1_DROME (Q03042) cGMP-dependent protein kinase, isozyme 1 (EC 2.7.11.12)| (CGK) Length = 768 Score = 115 bits (289), Expect = 7e-26 Identities = 64/186 (34%), Positives = 100/186 (53%), Gaps = 2/186 (1%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + RL+ TF+D +YM LE+C GGE++ + +G ++ A+F ++ EYLH+ Sbjct: 517 PFICRLYRTFRDEKYVYMLLEACMGGEIWTMLRDRGSFEDNAAQFIIGCVLQAFEYLHAR 576 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+KPENL+L G++KI DFG K T+ + TF GT YV PE Sbjct: 577 GIIYRDLKPENLMLDERGYVKIVDFGFAKQI----------GTSSKTWTFCGTPEYVAPE 626 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRII--ARDLRFPEFFSDEAR 535 ++ + D WALG + ++L+G+ PF + I+ + FP+ S A Sbjct: 627 IILNKGHDRAVDYWALGILIHELLNGTPPFSAPDPMQTYNLILKGIDMIAFPKHISRWAV 686 Query: 536 DLIDKL 553 LI +L Sbjct: 687 QLIKRL 692
>CBK1_PNECA (Q6TGC6) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1)| Length = 507 Score = 115 bits (289), Expect = 7e-26 Identities = 74/227 (32%), Positives = 110/227 (48%), Gaps = 42/227 (18%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P V+ L+++FQDS LY+ +E GG+L +++ SED RFY AE + +E +H + Sbjct: 184 PWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIKYDTFSEDVTRFYIAECILAIEAVHKL 243 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFG---------------------------------- 259 G IHRD+KP+N+L+ GHIK++DFG Sbjct: 244 GFIHRDIKPDNILIDKTGHIKLSDFGLSMGFHKTHDNAYYQRLFESKINTSTSSTQNSLM 303 Query: 260 --SVKPTVDTPIKVLPNSTNER--ACTFVGTAAYVPPEVLNSAPATFGNDLWALGCTLFQ 427 ++ T+ + K+ N R A + VGT Y+ PE+ D W+LG +F+ Sbjct: 304 VDTISLTMSSKDKIATWKKNRRIMAYSTVGTPDYIAPEIFTQHGYGQECDWWSLGAIMFE 363 Query: 428 MLSGSSPFKDASEWLIFQRII--ARDLRFPE--FFSDEARDLIDKLL 556 L G PF + +++II +L FPE S EA DLI KLL Sbjct: 364 CLIGWPPFCSENAHETYRKIINWRENLYFPEDLHLSAEAEDLIRKLL 410
>PLK3_CAEEL (Q20845) Serine/threonine-protein kinase plk-3 (EC 2.7.11.21)| (Polo-like kinase 3) Length = 615 Score = 115 bits (289), Expect = 7e-26 Identities = 67/189 (35%), Positives = 97/189 (51%) Frame = +2 Query: 8 VIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSVGL 187 +++ F+DS ++Y LE C L + ++G L+E EARFY ++ + +++LH++ + Sbjct: 95 IVQFHHFFEDSQNVYFTLELCSKNSLMELNKQRGPLTEHEARFYTIQVAEGVKHLHNLQI 154 Query: 188 IHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPEVL 367 IHRD+K NL L +KI DFG NE+ T GT Y+ PEVL Sbjct: 155 IHRDLKLGNLFLNEHLQVKIGDFGLATFC----------EKNEKKMTRGGTPNYIAPEVL 204 Query: 368 NSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDLID 547 N F D+WA+GC L+ +L GS PF+ + RI D PE S A LI Sbjct: 205 NETGHAFEVDIWAIGCILYVLLFGSPPFESRRVQETYVRIKNNDYVVPENASPTANRLIR 264 Query: 548 KLLDVDPTK 574 LLD P + Sbjct: 265 SLLDPVPDR 273
>ROCK1_RABIT (O77819) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (cAMP-dependent protein kinase ROCK-I) (CePKA) (Corneal epithelial Rho-associated-Ser/Thr kinase 1) (HEB Length = 1354 Score = 115 bits (288), Expect = 9e-26 Identities = 74/189 (39%), Positives = 106/189 (56%), Gaps = 8/189 (4%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P V++LF+ FQD LYM +E GG+L + ++ + E ARFY AE+V L+ +HS+ Sbjct: 134 PWVVQLFYAFQDDRYLYMVMEYMPGGDLVN-LMSNYDVPEKWARFYTAEVVLALDAIHSM 192 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G IHRDVKP+N+LL GH+K+ADFG+ + R T VGT Y+ PE Sbjct: 193 GFIHRDVKPDNMLLDKSGHLKLADFGTCMK--------MNKEGMVRCDTAVGTPDYISPE 244 Query: 362 VLNS--APATFGN--DLWALGCTLFQMLSGSSPFKDASEWLIFQRII--ARDLRFPE--F 517 VL S +G D W++G L++ML G +PF S + +I+ L FP+ Sbjct: 245 VLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDND 304 Query: 518 FSDEARDLI 544 S EA++LI Sbjct: 305 ISKEAKNLI 313
>ROCK1_MOUSE (P70335) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) Length = 1354 Score = 115 bits (288), Expect = 9e-26 Identities = 74/189 (39%), Positives = 106/189 (56%), Gaps = 8/189 (4%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P V++LF+ FQD LYM +E GG+L + ++ + E ARFY AE+V L+ +HS+ Sbjct: 134 PWVVQLFYAFQDDRYLYMVMEYMPGGDLVN-LMSNYDVPEKWARFYTAEVVLALDAIHSM 192 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G IHRDVKP+N+LL GH+K+ADFG+ + R T VGT Y+ PE Sbjct: 193 GFIHRDVKPDNMLLDKSGHLKLADFGTCMK--------MNKEGMVRCDTAVGTPDYISPE 244 Query: 362 VLNS--APATFGN--DLWALGCTLFQMLSGSSPFKDASEWLIFQRII--ARDLRFPE--F 517 VL S +G D W++G L++ML G +PF S + +I+ L FP+ Sbjct: 245 VLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDND 304 Query: 518 FSDEARDLI 544 S EA++LI Sbjct: 305 ISKEAKNLI 313
>ROCK1_HUMAN (Q13464) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen) Length = 1354 Score = 115 bits (288), Expect = 9e-26 Identities = 74/189 (39%), Positives = 106/189 (56%), Gaps = 8/189 (4%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P V++LF+ FQD LYM +E GG+L + ++ + E ARFY AE+V L+ +HS+ Sbjct: 134 PWVVQLFYAFQDDRYLYMVMEYMPGGDLVN-LMSNYDVPEKWARFYTAEVVLALDAIHSM 192 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G IHRDVKP+N+LL GH+K+ADFG+ + R T VGT Y+ PE Sbjct: 193 GFIHRDVKPDNMLLDKSGHLKLADFGTCMK--------MNKEGMVRCDTAVGTPDYISPE 244 Query: 362 VLNS--APATFGN--DLWALGCTLFQMLSGSSPFKDASEWLIFQRII--ARDLRFPE--F 517 VL S +G D W++G L++ML G +PF S + +I+ L FP+ Sbjct: 245 VLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDND 304 Query: 518 FSDEARDLI 544 S EA++LI Sbjct: 305 ISKEAKNLI 313
>PLO1_SCHPO (P50528) Serine/threonine-protein kinase plo1 (EC 2.7.11.21)| Length = 683 Score = 115 bits (288), Expect = 9e-26 Identities = 65/194 (33%), Positives = 104/194 (53%), Gaps = 4/194 (2%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ F+DS ++Y+ LE CE L + + ++ +L+E E R+ +I+ L+Y+H Sbjct: 98 PNIVGFIDCFEDSTNIYLILELCEHKSLMELLRKRKQLTEPEVRYLMMQILGALKYMHKK 157 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +IHRD+K N++L ++KI DFG + L ER T GT Y+ PE Sbjct: 158 RVIHRDLKLGNIMLDESNNVKIGDFG---------LAALLMDDEERKMTICGTPNYIAPE 208 Query: 362 VLNSAPA--TFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPE--FFSDE 529 +L ++ +F DLW+ G ++ +L G PF+D I+++I A FP S E Sbjct: 209 ILFNSKEGHSFEVDLWSAGVVMYALLIGKPPFQDKEVKTIYRKIKANSYSFPSNVDISAE 268 Query: 530 ARDLIDKLLDVDPT 571 A+DLI LL DP+ Sbjct: 269 AKDLISSLLTHDPS 282
>ORB6_SCHPO (O13310) Serine/threonine-protein kinase orb6 (EC 2.7.11.1)| Length = 469 Score = 115 bits (288), Expect = 9e-26 Identities = 74/221 (33%), Positives = 109/221 (49%), Gaps = 36/221 (16%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P V+ L++ FQDS LY+ +E GG+L ++ SED RFY AE V + +H + Sbjct: 151 PWVVSLYYAFQDSLYLYLIMEFLPGGDLMTMLINYDTFSEDVTRFYMAECVLAIADVHRM 210 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFG-------------SVKPTVDTPIK--------VL 298 G IHRD+KP+N+L+ DGHIK++DFG +KP +K L Sbjct: 211 GYIHRDIKPDNILIDRDGHIKLSDFGLSTGFYKQDQSASYMKPRTGNTVKRGQMVDAIWL 270 Query: 299 PNSTNERACTF-----------VGTAAYVPPEVLNSAPATFGNDLWALGCTLFQMLSGSS 445 S+ ++ T+ VGT Y+ PE+ D W+LG +F+ L G Sbjct: 271 TMSSKDKMATWKKNRRVMAYSTVGTPDYIAPEIFLQQGYGQDCDWWSLGAIMFECLIGWP 330 Query: 446 PFKDASEWLIFQRII--ARDLRFPE--FFSDEARDLIDKLL 556 PF + +++II L FP S EARDL+D+L+ Sbjct: 331 PFCSENSHETYRKIINWRETLTFPNDIHLSIEARDLMDRLM 371
>ROCK1_RAT (Q63644) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (p150 RhoA-binding kinase ROK beta) (Liver regeneration-related protein LRRG199) Length = 1369 Score = 115 bits (288), Expect = 9e-26 Identities = 74/189 (39%), Positives = 106/189 (56%), Gaps = 8/189 (4%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P V++LF+ FQD LYM +E GG+L + ++ + E ARFY AE+V L+ +HS+ Sbjct: 134 PWVVQLFYAFQDDRYLYMVMEYMPGGDLVN-LMSNYDVPEKWARFYTAEVVLALDAIHSM 192 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G IHRDVKP+N+LL GH+K+ADFG+ + R T VGT Y+ PE Sbjct: 193 GFIHRDVKPDNMLLDKSGHLKLADFGTCMK--------MNKEGMVRCDTAVGTPDYISPE 244 Query: 362 VLNS--APATFGN--DLWALGCTLFQMLSGSSPFKDASEWLIFQRII--ARDLRFPE--F 517 VL S +G D W++G L++ML G +PF S + +I+ L FP+ Sbjct: 245 VLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDND 304 Query: 518 FSDEARDLI 544 S EA++LI Sbjct: 305 ISKEAKNLI 313
>KPSH1_HUMAN (P11801) Serine/threonine-protein kinase H1 (EC 2.7.11.1) (PSK-H1)| Length = 423 Score = 115 bits (287), Expect = 1e-25 Identities = 72/197 (36%), Positives = 107/197 (54%), Gaps = 10/197 (5%) Frame = +2 Query: 8 VIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSVGL 187 +I+L F+ +YM +E GGELFD+I+ KG +E +A ++D + YLH++G+ Sbjct: 154 IIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGI 213 Query: 188 IHRDVKPENLLL---TSDGHIKIADFG---SVKPTVDTPIKVLPNSTNERACTFVGTAAY 349 HRD+KPENLL +D I I DFG + K D +K T GT Y Sbjct: 214 THRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMK-----------TTCGTPEY 262 Query: 350 VPPEVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFP----EF 517 + PEVL P T D+WALG + +LSG+ PF+D + ++++I+ + Sbjct: 263 IAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPWPS 322 Query: 518 FSDEARDLIDKLLDVDP 568 S+ A+D ID+LL VDP Sbjct: 323 VSNLAKDFIDRLLTVDP 339
>KPC3_DROME (P13678) Protein kinase C (EC 2.7.11.13) (PKC) (dPKC98F)| Length = 634 Score = 114 bits (286), Expect = 2e-25 Identities = 64/189 (33%), Positives = 98/189 (51%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P + L FQ L+ +E GG+L QI + R A FYAAE+ L++LH+ Sbjct: 362 PFLTALHSCFQTPDRLFFVMEYVNGGDLMFQIQKARRFEASRAAFYAAEVTLALQFLHTH 421 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+K +N+LL +GH K+ADFG K + TF GT Y+ PE Sbjct: 422 GVIYRDLKLDNILLDQEGHCKLADFGMCKEGI---------MNGMLTTTFCGTPDYIAPE 472 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 +L D WALG +++M++G PF+ +E +F I+ D+ +P + S EA + Sbjct: 473 ILKEQEYGASVDWWALGVLMYEMMAGQPPFEADNEDELFDSIMHDDVLYPVWLSREAVSI 532 Query: 542 IDKLLDVDP 568 + L +P Sbjct: 533 LKGFLTKNP 541
>PLK2_CAEEL (Q9N2L7) Serine/threonine-protein kinase plk-2 (EC 2.7.11.21)| (Polo-like kinase 2) Length = 632 Score = 114 bits (286), Expect = 2e-25 Identities = 68/189 (35%), Positives = 103/189 (54%) Frame = +2 Query: 8 VIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSVGL 187 V++L+ F+D ++Y+ LE C L + R+ ++E EAR++ +IV+ + YLH++ + Sbjct: 96 VVKLYHFFEDKSNVYITLELCPRRSLMELHKRRKAVTEPEARYFTYQIVEGVLYLHNLKI 155 Query: 188 IHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPEVL 367 +HRD+K NL L + +KI DFG + T D +ER T GT Y+ PEVL Sbjct: 156 VHRDLKLGNLFLNDELQVKIGDFG-LATTCD---------NDERKKTLCGTPNYIAPEVL 205 Query: 368 NSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDLID 547 N +F DLWA+GC L+ +L G PF+ S + RI + P S A LI Sbjct: 206 NKIGHSFEVDLWAIGCILYILLFGHPPFESKSLEETYSRIKNNNYVIPTSASAAASQLIR 265 Query: 548 KLLDVDPTK 574 LLD P++ Sbjct: 266 VLLDPVPSR 274
>RAD53_YEAST (P22216) Serine/threonine-protein kinase RAD53 (EC 2.7.11.1)| (Serine-protein kinase 1) Length = 821 Score = 114 bits (286), Expect = 2e-25 Identities = 70/212 (33%), Positives = 112/212 (52%), Gaps = 23/212 (10%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++RL ++D+ S YM +E GG+L D + G + ED R + +I+ ++Y+HS+ Sbjct: 254 PRIVRLKGFYEDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGREISRQILTAIKYIHSM 313 Query: 182 GLIHRDVKPENLLLTSDGH--IKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVP 355 G+ HRD+KP+N+L+ D +KI DFG KV N + + TF GT AYV Sbjct: 314 GISHRDLKPDNILIEQDDPVLVKITDFGLA--------KVQGNGSFMK--TFCGTLAYVA 363 Query: 356 PEVLNSAPATFGN-------------DLWALGCTLFQMLSGSSPFKDASEWLIFQRI--- 487 PEV+ + D+W++GC ++ +L+G PF +++ ++++I Sbjct: 364 PEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGSTQDQLYKQIGRG 423 Query: 488 -----IARDLRFPEFFSDEARDLIDKLLDVDP 568 +D R S+EARD ID LL VDP Sbjct: 424 SYHEGPLKDFR----ISEEARDFIDSLLQVDP 451
>PCK2_SCHPO (P36583) Protein kinase C-like 2 (EC 2.7.11.13)| Length = 1016 Score = 114 bits (286), Expect = 2e-25 Identities = 64/191 (33%), Positives = 102/191 (53%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ L FQ +Y ++ GG+L I ++ + S A+FYAAE+ L+Y H Sbjct: 744 PFLVNLHSCFQTETRIYFVMDFVSGGDLMLHIQQE-QFSRRRAQFYAAEVCLALKYFHDN 802 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 G+I+RD+K +N+LL+ DGH+K+AD+G K + + TF GT ++ PE Sbjct: 803 GIIYRDLKLDNILLSPDGHVKVADYGLCKEDM---------WHDNTTATFCGTPEFMAPE 853 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 +L T D WA G ++QML G SPF+ E IF I++ + +P ++ + Sbjct: 854 ILLEQQYTRSVDWWAFGVLIYQMLLGQSPFRGEDEEEIFDAILSDEPLYPIHMPRDSVSI 913 Query: 542 IDKLLDVDPTK 574 + +LL DP K Sbjct: 914 LQQLLTRDPKK 924
>MARK3_RAT (Q8VHF0) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| Length = 797 Score = 114 bits (286), Expect = 2e-25 Identities = 65/193 (33%), Positives = 105/193 (54%), Gaps = 2/193 (1%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +++LF + +LY+ +E GGE+FD +V GR+ E EAR +IV ++Y H Sbjct: 113 PNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQK 172 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFG-SVKPTVDTPIKVLPNSTNERACTFVGTAAYVPP 358 ++HRD+K ENLLL +D +IKI DFG S + TV + + TF G+ Y P Sbjct: 173 RIVHRDLKAENLLLDADMNIKITDFGFSNEFTVGSKLD-----------TFCGSPPYAAP 221 Query: 359 EVLNSAPATFGN-DLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEAR 535 E+ D+W+LG L+ ++SGS PF + + +R++ R P + S + Sbjct: 222 ELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCE 281 Query: 536 DLIDKLLDVDPTK 574 +L+ + L ++P K Sbjct: 282 NLLKRFLVLNPVK 294
>KPC1_LYTPI (Q25378) Protein kinase C (EC 2.7.11.13)| Length = 658 Score = 114 bits (286), Expect = 2e-25 Identities = 68/182 (37%), Positives = 96/182 (52%) Frame = +2 Query: 29 FQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSVGLIHRDVKP 208 FQ L+ +E GG+L QI + G+ E A FYAAEI L YLHS G+I+RD+K Sbjct: 393 FQTMDRLFFVMEFVNGGDLMFQIQKVGKFREPHAVFYAAEIAVGLFYLHSQGVIYRDLKL 452 Query: 209 ENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPEVLNSAPATF 388 +N+L+ ++GHIKIADFG K + + + TF GT Y+ PE++ P Sbjct: 453 DNVLVDAEGHIKIADFGMCKEHM---------NEGDTTRTFCGTPDYIAPEIVAYQPYGK 503 Query: 389 GNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDLIDKLLDVDP 568 D WA G L++ML+G PF E +FQ I+ +P+ S E+ + L P Sbjct: 504 AVDWWAFGVLLYEMLAGQPPFDGEDEDELFQSIMEHVPSYPKSMSRESVTMCKGFLTKHP 563 Query: 569 TK 574 K Sbjct: 564 GK 565
>SN1L2_CHICK (Q9IA88) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Qin-induced kinase) Length = 798 Score = 114 bits (286), Expect = 2e-25 Identities = 67/192 (34%), Positives = 102/192 (53%), Gaps = 1/192 (0%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +I+L+ + LY+ E + GE+FD + G LSE EAR +I+ +EY HS Sbjct: 83 PHIIKLYQVMETKDMLYIVTEFAKNGEMFDHLTSNGHLSESEARKKFWQILSAVEYCHSH 142 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 ++HRD+K ENLLL ++ +IK+ADFG + E T+ G+ Y PE Sbjct: 143 HIVHRDLKTENLLLDANMNIKLADFGFGN----------FYKSGEPLSTWCGSPPYAAPE 192 Query: 362 VLNSAPATFGN-DLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARD 538 V + D+W+LG L+ ++ GS PF + + QR++ R P F S++ Sbjct: 193 VFEGKEYEGPHLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPYFMSEDCET 252 Query: 539 LIDKLLDVDPTK 574 LI ++L VDPTK Sbjct: 253 LIRRMLVVDPTK 264
>KCC1D_MOUSE (Q8BW96) Calcium/calmodulin-dependent protein kinase type 1D (EC| 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) (mCKLiK) Length = 385 Score = 114 bits (286), Expect = 2e-25 Identities = 66/196 (33%), Positives = 103/196 (52%), Gaps = 7/196 (3%) Frame = +2 Query: 8 VIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSVGL 187 ++ L ++ LY+ ++ GGELFD+IV KG +E +A +++D + YLH +G+ Sbjct: 81 IVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGI 140 Query: 188 IHRDVKPENLLLTS---DGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPP 358 +HRD+KPENLL S + I I+DFG K + T GT YV P Sbjct: 141 VHRDLKPENLLYYSQDEESKIMISDFGLSK----------MEGKGDVMSTACGTPGYVAP 190 Query: 359 EVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFP----EFFSD 526 EVL P + D W++G + +L G PF D ++ +F++I+ + F + SD Sbjct: 191 EVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISD 250 Query: 527 EARDLIDKLLDVDPTK 574 A+D I L++ DP K Sbjct: 251 SAKDFIRNLMEKDPNK 266
>KCC1D_HUMAN (Q8IU85) Calcium/calmodulin-dependent protein kinase type 1D (EC| 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) Length = 385 Score = 114 bits (286), Expect = 2e-25 Identities = 66/196 (33%), Positives = 103/196 (52%), Gaps = 7/196 (3%) Frame = +2 Query: 8 VIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSVGL 187 ++ L ++ LY+ ++ GGELFD+IV KG +E +A +++D + YLH +G+ Sbjct: 81 IVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGI 140 Query: 188 IHRDVKPENLLLTS---DGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPP 358 +HRD+KPENLL S + I I+DFG K + T GT YV P Sbjct: 141 VHRDLKPENLLYYSQDEESKIMISDFGLSK----------MEGKGDVMSTACGTPGYVAP 190 Query: 359 EVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFP----EFFSD 526 EVL P + D W++G + +L G PF D ++ +F++I+ + F + SD Sbjct: 191 EVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISD 250 Query: 527 EARDLIDKLLDVDPTK 574 A+D I L++ DP K Sbjct: 251 SAKDFIRNLMEKDPNK 266
>KPSH1_MOUSE (Q91YA2) Serine/threonine-protein kinase H1 (EC 2.7.11.1) (PSK-H1)| Length = 423 Score = 114 bits (285), Expect = 2e-25 Identities = 72/197 (36%), Positives = 107/197 (54%), Gaps = 10/197 (5%) Frame = +2 Query: 8 VIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSVGL 187 +I+L F+ +YM +E GGELFD+I+ KG +E +A ++D + YLH++G+ Sbjct: 154 IIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGI 213 Query: 188 IHRDVKPENLLL---TSDGHIKIADFG---SVKPTVDTPIKVLPNSTNERACTFVGTAAY 349 HRD+KPENLL +D I I DFG + K D +K T GT Y Sbjct: 214 THRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMK-----------TTCGTPEY 262 Query: 350 VPPEVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFP----EF 517 + PEVL P T D+WALG + +LSG+ PF+D + ++++I+ + Sbjct: 263 IAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYLGEPWPS 322 Query: 518 FSDEARDLIDKLLDVDP 568 S+ A+D ID+LL VDP Sbjct: 323 VSNLAKDFIDRLLTVDP 339
>MARK2_MOUSE (Q05512) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1) Length = 776 Score = 114 bits (285), Expect = 2e-25 Identities = 64/192 (33%), Positives = 103/192 (53%), Gaps = 1/192 (0%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P +++LF + +LY+ +E GGE+FD +V GR+ E EAR +IV ++Y H Sbjct: 110 PNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVLHVQYCHQK 169 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 ++HRD+K ENLLL +D +IKIADFG + + TF G+ Y PE Sbjct: 170 FIVHRDLKAENLLLDADMNIKIADFGFSNEF----------TFGNKLDTFCGSPPYAAPE 219 Query: 362 VLNSAPATFGN-DLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARD 538 + D+W+LG L+ ++SGS PF + + +R++ R P + S + + Sbjct: 220 LFQGKKIDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCEN 279 Query: 539 LIDKLLDVDPTK 574 L+ K L ++P+K Sbjct: 280 LLKKFLILNPSK 291
>ROCK2_HUMAN (O75116) Rho-associated protein kinase 2 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2) Length = 1388 Score = 114 bits (285), Expect = 2e-25 Identities = 74/189 (39%), Positives = 107/189 (56%), Gaps = 8/189 (4%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P V++LF+ FQD LYM +E GG+L + ++ + E A+FY AE+V L+ +HS+ Sbjct: 150 PWVVQLFYAFQDDRYLYMVMEYMPGGDLVN-LMSNYDVPEKWAKFYTAEVVLALDAIHSM 208 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 GLIHRDVKP+N+LL GH+K+ADFG+ +T + T VGT Y+ PE Sbjct: 209 GLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGM--------VHCDTAVGTPDYISPE 260 Query: 362 VLNS--APATFGN--DLWALGCTLFQMLSGSSPFKDASEWLIFQRII--ARDLRFPE--F 517 VL S +G D W++G L++ML G +PF S + +I+ L FPE Sbjct: 261 VLKSQGGDGFYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDAE 320 Query: 518 FSDEARDLI 544 S A++LI Sbjct: 321 ISKHAKNLI 329
>PKN2_RAT (O08874) Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein| kinase C-like 2) (Protein-kinase C-related kinase 2) (Protease-activated kinase 2) (PAK-2) (Fragment) Length = 842 Score = 114 bits (284), Expect = 3e-25 Identities = 68/191 (35%), Positives = 100/191 (52%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ LF FQ + +E GG+L I SE A FYAA +V L+YLH Sbjct: 582 PFLVNLFACFQTKEHVCFVMEYAAGGDLMMHI-HTDVFSEPRAVFYAACVVLGLQYLHEH 640 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +++RD+K +NLLL ++ +KIADFG K + +R TF GT ++ PE Sbjct: 641 KIVYRDLKLDNLLLDTEASVKIADFGLCKEGM---------GYGDRTSTFCGTPEFLAPE 691 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 VL T D W LG +++ML G SPF E +F I+ ++R+P F S EA + Sbjct: 692 VLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISI 751 Query: 542 IDKLLDVDPTK 574 + +LL +P + Sbjct: 752 MRRLLRRNPER 762
>KPSH1_PINFU (Q4KTY1) Serine/threonine-protein kinase H1 homolog (EC 2.7.11.1)| Length = 415 Score = 113 bits (283), Expect = 3e-25 Identities = 68/194 (35%), Positives = 105/194 (54%), Gaps = 7/194 (3%) Frame = +2 Query: 8 VIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSVGL 187 +I+L F+ +YM +E GGELFD+I+ KG +E +A ++D ++YLH +G+ Sbjct: 135 IIQLIEVFETKDKVYMVMELATGGELFDRIIAKGSFTERDATRVLNMVLDGVKYLHGLGI 194 Query: 188 IHRDVKPENLLLTSDGH---IKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPP 358 HRD+KPENLL GH I I DFG + + P + C GT Y+ P Sbjct: 195 THRDLKPENLLYYHPGHDSKIMITDFGL------SSTRKGPENFMRTTC---GTPEYIAP 245 Query: 359 EVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFP-EFFSD--- 526 E++ P D+WA+G + +LSG+ PF D ++ +++ I+ + E + D Sbjct: 246 EIIARKPYMCQVDMWAVGVITYILLSGTMPFDDENKTRLYRLILKAKYSYAGEHWKDVSA 305 Query: 527 EARDLIDKLLDVDP 568 +A+D IDKLL V P Sbjct: 306 QAKDFIDKLLVVSP 319
>MAST3_HUMAN (O60307) Microtubule-associated serine/threonine-protein kinase 3 (EC| 2.7.11.1) Length = 1309 Score = 113 bits (283), Expect = 3e-25 Identities = 70/198 (35%), Positives = 105/198 (53%), Gaps = 9/198 (4%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P V+ +F +F+ L M +E EGG+ + G L D AR Y AE V LEYLH+ Sbjct: 425 PFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARLYFAETVLALEYLHNY 484 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVK-PTVDTPIKVLPNSTNERACTFV-----GTA 343 G++HRD+KP+NLL+TS GHIK+ DFG K + + + A F+ GT Sbjct: 485 GIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIEKDAREFIDKQVCGTP 544 Query: 344 AYVPPEVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFP---E 514 Y+ PEV+ D WA+G L++ L G PF + +F ++++ ++ +P E Sbjct: 545 EYIAPEVIFRQGYGKPVDWWAMGVVLYEFLVGCVPFFGDTPEELFGQVVSDEIMWPEGDE 604 Query: 515 FFSDEARDLIDKLLDVDP 568 +A+DLI +LL P Sbjct: 605 ALPADAQDLITRLLRQSP 622
>PKN1_HUMAN (Q16512) Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein| kinase C-like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-like PKN) (Serine-threonine protein kinase N) (Protein kinase PKN-alpha) Length = 942 Score = 113 bits (283), Expect = 3e-25 Identities = 68/191 (35%), Positives = 102/191 (53%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P ++ LF FQ + +E GG+L I SE A FY+A +V L++LH Sbjct: 676 PFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHI-HSDVFSEPRAIFYSACVVLGLQFLHEH 734 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 +++RD+K +NLLL ++G++KIADFG K + +R TF GT ++ PE Sbjct: 735 KIVYRDLKLDNLLLDTEGYVKIADFGLCKEGM---------GYGDRTSTFCGTPEFLAPE 785 Query: 362 VLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPEFFSDEARDL 541 VL T D W LG L++ML G SPF E +F I+ ++R+P F S EA + Sbjct: 786 VLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAEAIGI 845 Query: 542 IDKLLDVDPTK 574 + +LL +P + Sbjct: 846 MRRLLRRNPER 856
>CCAMK_PEA (Q6RET6) Calcium and calcium/calmodulin-dependent| serine/threonine-protein kinase (EC 2.7.11.17) (PsCCaMK) (Ps-SYM9) (Fragment) Length = 527 Score = 113 bits (283), Expect = 3e-25 Identities = 74/200 (37%), Positives = 105/200 (52%), Gaps = 9/200 (4%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P VI L+ ++D+ +++ LE C GGELFD+IV + + SE EA +IV LE +H Sbjct: 114 PNVIDLYDVYEDTNGVHLVLELCSGGELFDRIVAQDKYSETEASTVVHQIVAGLEAIHRA 173 Query: 182 GLIHRDVKPENLL---LTSDGHIKIADFG--SVKPTVDTPIKVLPNSTNERACTFVGTAA 346 +IHRD+KPEN L + D +KI DFG SV+ D + + G+ Sbjct: 174 NIIHRDLKPENCLFLDVGKDSSLKIMDFGLSSVEEFTDPVVGLF------------GSID 221 Query: 347 YVPPEVLNSAPATFGNDLWALGCTLFQMLSGSSPFKDASEWLIFQRIIARDLRFPE---- 514 YV PE L+ T +D+W+LG L+ +LSG PF + Q I+ + F E Sbjct: 222 YVSPEALSQGKITTKSDMWSLGVILYILLSGYPPFIAQNNRQKQQMILNGNFSFYEKTWK 281 Query: 515 FFSDEARDLIDKLLDVDPTK 574 S A++LI LL VDP K Sbjct: 282 GISQSAKNLISSLLTVDPAK 301
>ROCK2_RAT (Q62868) Rho-associated protein kinase 2 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 2) (p164 ROCK-2) (RhoA-binding kinase 2) (p150 ROK-alpha) (ROKalpha) Length = 1379 Score = 113 bits (283), Expect = 3e-25 Identities = 75/189 (39%), Positives = 106/189 (56%), Gaps = 8/189 (4%) Frame = +2 Query: 2 PGVIRLFFTFQDSYSLYMALESCEGGELFDQIVRKGRLSEDEARFYAAEIVDILEYLHSV 181 P V++LF FQD LYM +E GG+L + ++ + E A+FY AE+V L+ +HS+ Sbjct: 141 PWVVQLFCAFQDDRYLYMVMEYMPGGDLVN-LMSNYDVPEKWAKFYTAEVVLALDAIHSM 199 Query: 182 GLIHRDVKPENLLLTSDGHIKIADFGSVKPTVDTPIKVLPNSTNERACTFVGTAAYVPPE 361 GLIHRDVKP+N+LL GH+K+ADFG+ +T + T VGT Y+ PE Sbjct: 200 GLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGM--------VHCDTAVGTPDYISPE 251 Query: 362 VLNS--APATFGN--DLWALGCTLFQMLSGSSPFKDASEWLIFQRII--ARDLRFPE--F 517 VL S +G D W++G LF+ML G +PF S + +I+ L FPE Sbjct: 252 VLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDTE 311 Query: 518 FSDEARDLI 544 S A++LI Sbjct: 312 ISKHAKNLI 320 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 85,521,390 Number of Sequences: 219361 Number of extensions: 1849972 Number of successful extensions: 9426 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 7198 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 7615 length of database: 80,573,946 effective HSP length: 106 effective length of database: 57,321,680 effective search space used: 4815021120 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
