ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bags31g03 |
|---|---|
| Clone Library Name | barley_pub |
>APK1A_ARATH (Q06548) Protein kinase APK1A, chloroplast precursor (EC 2.7.11.1)| Length = 410 Score = 177 bits (448), Expect(2) = 5e-47 Identities = 82/130 (63%), Positives = 109/130 (83%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FGLAKDGP+GDK+HVSTRVMGT+GYAAPEY+ TGHLT+KSDVYSFGVVLLE++SGRR++D Sbjct: 222 FGLAKDGPIGDKSHVSTRVMGTHGYAAPEYLATGHLTTKSDVYSFGVVLLELLSGRRAVD 281 Query: 252 KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 KNRP+GE NLVEWA+P L +++ ++++D RL+ +S++ A K A L+ CL+ + K RP Sbjct: 282 KNRPSGERNLVEWAKPYLVNKRKIFRVIDNRLQDQYSMEEACKVATLSLRCLTTEIKLRP 341 Query: 432 LMSQVVEALK 461 MS+VV L+ Sbjct: 342 NMSEVVSHLE 351 Score = 30.0 bits (66), Expect(2) = 5e-47 Identities = 18/29 (62%), Positives = 18/29 (62%) Frame = +1 Query: 1 VIYRDFKTSNILLXFGIQCKALXILGLPK 87 VIYRDFKTSNILL K L GL K Sbjct: 199 VIYRDFKTSNILLDSEYNAK-LSDFGLAK 226
>APK1B_ARATH (P46573) Protein kinase APK1B, chloroplast precursor (EC 2.7.11.1)| Length = 412 Score = 176 bits (445), Expect(2) = 1e-46 Identities = 82/130 (63%), Positives = 107/130 (82%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FGLAKDGP GDK+HVSTR+MGTYGYAAPEY+ TGHLT+KSDVYS+GVVLLE++SGRR++D Sbjct: 223 FGLAKDGPTGDKSHVSTRIMGTYGYAAPEYLATGHLTTKSDVYSYGVVLLEVLSGRRAVD 282 Query: 252 KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 KNRP GE LVEWARPLL +++ ++++D RL+ +S++ A K A LA CL+ + K RP Sbjct: 283 KNRPPGEQKLVEWARPLLANKRKLFRVIDNRLQDQYSMEEACKVATLALRCLTFEIKLRP 342 Query: 432 LMSQVVEALK 461 M++VV L+ Sbjct: 343 NMNEVVSHLE 352 Score = 30.0 bits (66), Expect(2) = 1e-46 Identities = 18/29 (62%), Positives = 18/29 (62%) Frame = +1 Query: 1 VIYRDFKTSNILLXFGIQCKALXILGLPK 87 VIYRDFKTSNILL K L GL K Sbjct: 200 VIYRDFKTSNILLDSEYNAK-LSDFGLAK 227
>NAK_ARATH (P43293) Probable serine/threonine-protein kinase NAK (EC 2.7.11.1)| Length = 389 Score = 177 bits (450), Expect(2) = 2e-46 Identities = 82/132 (62%), Positives = 109/132 (82%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FGLA+DGP+GD +HVSTRVMGT GYAAPEY+ TGHL+ KSDVYSFGVVLLE++SGRR++D Sbjct: 222 FGLARDGPMGDNSHVSTRVMGTQGYAAPEYLATGHLSVKSDVYSFGVVLLELLSGRRAID 281 Query: 252 KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 KN+P GEHNLV+WARP L ++R +++DPRL+G +S+ A K A LA C+S D K+RP Sbjct: 282 KNQPVGEHNLVDWARPYLTNKRRLLRVMDPRLQGQYSLTRALKIAVLALDCISIDAKSRP 341 Query: 432 LMSQVVEALKPL 467 M+++V+ ++ L Sbjct: 342 TMNEIVKTMEEL 353 Score = 27.7 bits (60), Expect(2) = 2e-46 Identities = 13/20 (65%), Positives = 13/20 (65%) Frame = +1 Query: 1 VIYRDFKTSNILLXFGIQCK 60 VIYRDFK SNILL K Sbjct: 199 VIYRDFKASNILLDSNYNAK 218
>PBS1_ARATH (Q9FE20) Serine/threonine-protein kinase PBS1 (EC 2.7.11.1)| (AvrPphB susceptible protein 1) Length = 456 Score = 166 bits (421), Expect(2) = 3e-44 Identities = 79/133 (59%), Positives = 97/133 (72%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FGLAK GP GDK+HVSTRVMGTYGY APEY MTG LT KSDVYSFGVV LE+++GR+++D Sbjct: 232 FGLAKLGPTGDKSHVSTRVMGTYGYCAPEYAMTGQLTVKSDVYSFGVVFLELITGRKAID 291 Query: 252 KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 P+GE NLV WARPL +R++F KL DPRL+G F + +A +A C+ RP Sbjct: 292 SEMPHGEQNLVAWARPLFNDRRKFIKLADPRLKGRFPTRALYQALAVASMCIQEQAATRP 351 Query: 432 LMSQVVEALKPLA 470 L++ VV AL LA Sbjct: 352 LIADVVTALSYLA 364 Score = 31.2 bits (69), Expect(2) = 3e-44 Identities = 18/30 (60%), Positives = 20/30 (66%) Frame = +1 Query: 1 VIYRDFKTSNILLXFGIQCKALXILGLPKM 90 VIYRDFK+SNILL G K L GL K+ Sbjct: 209 VIYRDFKSSNILLDEGFHPK-LSDFGLAKL 237
>RLCK7_ARATH (Q9LQQ8) Probable serine/threonine-protein kinase RLCKVII (EC| 2.7.11.1) Length = 423 Score = 160 bits (404), Expect(2) = 7e-41 Identities = 76/133 (57%), Positives = 98/133 (73%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FGLAK GP GDKTHVSTRVMGTYGY AP+Y MTG LT KSD+YSFGVVLLE+++GR+++D Sbjct: 249 FGLAKVGPSGDKTHVSTRVMGTYGYCAPDYAMTGQLTFKSDIYSFGVVLLELITGRKAID 308 Query: 252 KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 + + NLV WARPL +R+ F K+VDP L+G + V+G +A ++ C+ P RP Sbjct: 309 NTKTRKDQNLVGWARPLFKDRRNFPKMVDPLLQGQYPVRGLYQALAISAMCVQEQPTMRP 368 Query: 432 LMSQVVEALKPLA 470 ++S VV AL LA Sbjct: 369 VVSDVVLALNFLA 381 Score = 26.6 bits (57), Expect(2) = 7e-41 Identities = 17/30 (56%), Positives = 18/30 (60%) Frame = +1 Query: 1 VIYRDFKTSNILLXFGIQCKALXILGLPKM 90 VIYRD K SNILL Q K L GL K+ Sbjct: 226 VIYRDLKCSNILLGEDYQPK-LSDFGLAKV 254
>CX32_ARATH (P27450) Probable serine/threonine-protein kinase Cx32, chloroplast| precursor (EC 2.7.11.1) Length = 419 Score = 144 bits (362), Expect(2) = 5e-37 Identities = 66/130 (50%), Positives = 95/130 (73%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FGLAK GP +K+HV+TR+MGTYGYAAPEY+ TGHL KSDV++FGVVLLE+M+G + + Sbjct: 237 FGLAKLGPADEKSHVTTRIMGTYGYAAPEYMATGHLYVKSDVFAFGVVLLEIMTGLTAHN 296 Query: 252 KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 RP G+ +LV+W RP L + R +++D ++G ++ K A + A++ +C+ DPK RP Sbjct: 297 TKRPRGQESLVDWLRPELSNKHRVKQIMDKGIKGQYTTKVATEMARITLSCIEPDPKNRP 356 Query: 432 LMSQVVEALK 461 M +VVE L+ Sbjct: 357 HMKEVVEVLE 366 Score = 29.6 bits (65), Expect(2) = 5e-37 Identities = 17/30 (56%), Positives = 18/30 (60%) Frame = +1 Query: 1 VIYRDFKTSNILLXFGIQCKALXILGLPKM 90 VIYRDFK SNILL K L GL K+ Sbjct: 214 VIYRDFKASNILLDSNYDAK-LSDFGLAKL 242
>TMK1_ARATH (P43298) Putative receptor protein kinase TMK1 precursor (EC| 2.7.11.1) Length = 942 Score = 101 bits (252), Expect(2) = 4e-22 Identities = 53/134 (39%), Positives = 81/134 (60%), Gaps = 2/134 (1%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FGL + P G K + TR+ GT+GY APEY +TG +T+K DVYSFGV+L+E+++GR+S+D Sbjct: 736 FGLVRLAPEG-KGSIETRIAGTFGYLAPEYAVTGRVTTKVDVYSFGVILMELITGRKSLD 794 Query: 252 KNRPNGEHNLVEW-ARPLLGERQRFYKLVDPRLE-GNFSVKGAQKAAQLARACLSRDPKA 425 +++P +LV W R + + F K +D ++ ++ A+LA C +R+P Sbjct: 795 ESQPEESIHLVSWFKRMYINKEASFKKAIDTTIDLDEETLASVHTVAELAGHCCAREPYQ 854 Query: 426 RPLMSQVVEALKPL 467 RP M V L L Sbjct: 855 RPDMGHAVNILSSL 868 Score = 21.9 bits (45), Expect(2) = 4e-22 Identities = 10/19 (52%), Positives = 13/19 (68%) Frame = +1 Query: 4 IYRDFKTSNILLXFGIQCK 60 I+RD K SNILL ++ K Sbjct: 714 IHRDLKPSNILLGDDMRAK 732
>NORK_PEA (Q8LKZ1) Nodulation receptor kinase precursor (EC 2.7.11.1)| Length = 924 Score = 99.4 bits (246), Expect(2) = 5e-22 Identities = 52/130 (40%), Positives = 76/130 (58%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FG +K P ++VS V GT GY PEY T L+ KSDV+SFGVVLLE++SGR ++ Sbjct: 740 FGFSKYAPQEGDSYVSLEVRGTAGYLDPEYYKTQQLSEKSDVFSFGVVLLEIVSGREPLN 799 Query: 252 KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 RP E +LVEWA+P + + ++VDP ++G + + + ++A CL RP Sbjct: 800 IKRPRVEWSLVEWAKPYI-RASKVDEIVDPGIKGGYHAEALWRVVEVALQCLEPYSTYRP 858 Query: 432 LMSQVVEALK 461 M +V L+ Sbjct: 859 CMVDIVRELE 868 Score = 23.9 bits (50), Expect(2) = 5e-22 Identities = 13/29 (44%), Positives = 17/29 (58%) Frame = +1 Query: 1 VIYRDFKTSNILLXFGIQCKALXILGLPK 87 VI+RD K+SNILL + C + G K Sbjct: 717 VIHRDVKSSNILLDHSM-CAKVADFGFSK 744
>NORK_MEDTR (Q8L4H4) Nodulation receptor kinase precursor (EC 2.7.11.1) (Does not| make infections protein 2) (Symbiosis receptor-like kinase) (MtSYMRK) Length = 925 Score = 99.0 bits (245), Expect(2) = 1e-21 Identities = 52/130 (40%), Positives = 76/130 (58%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FG +K P ++VS V GT GY PEY T L+ KSDV+SFGVVLLE++SGR ++ Sbjct: 741 FGFSKYAPQEGDSYVSLEVRGTAGYLDPEYYKTQQLSEKSDVFSFGVVLLEIVSGREPLN 800 Query: 252 KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 RP E +LVEWA+P + + ++VDP ++G + + + ++A CL RP Sbjct: 801 IKRPRIEWSLVEWAKPYI-RASKVDEIVDPGIKGGYHAEALWRVVEVALQCLEPYSTYRP 859 Query: 432 LMSQVVEALK 461 M +V L+ Sbjct: 860 CMVDIVRELE 869 Score = 23.1 bits (48), Expect(2) = 1e-21 Identities = 10/13 (76%), Positives = 12/13 (92%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 VI+RD K+SNILL Sbjct: 718 VIHRDVKSSNILL 730
>CRI4_MAIZE (O24585) Putative receptor protein kinase CRINKLY4 precursor (EC| 2.7.11.1) Length = 901 Score = 94.0 bits (232), Expect(2) = 5e-20 Identities = 55/130 (42%), Positives = 77/130 (59%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FGL+ GP T +S GT GY PEY +LT+KSDVYSFGVVLLE++SGR+++D Sbjct: 653 FGLSILGPADSGTPLSELPAGTLGYLDPEYYRLHYLTTKSDVYSFGVVLLEILSGRKAID 712 Query: 252 KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 G N+VEWA PL+ + + ++DP L ++ +K A +A C+ K RP Sbjct: 713 MQFEEG--NIVEWAVPLI-KAGDIFAILDPVLSPPSDLEALKKIASVACKCVRMRGKDRP 769 Query: 432 LMSQVVEALK 461 M +V AL+ Sbjct: 770 SMDKVTTALE 779 Score = 22.7 bits (47), Expect(2) = 5e-20 Identities = 9/13 (69%), Positives = 12/13 (92%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 VI+RD K+SNIL+ Sbjct: 630 VIHRDIKSSNILI 642
>BAK1_ARATH (Q94F62) BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1| precursor (EC 2.7.11.1) (BRI1-associated receptor kinase 1) (Somatic embryogenesis receptor-like kinase 3) Length = 615 Score = 94.7 bits (234), Expect(2) = 8e-20 Identities = 54/132 (40%), Positives = 82/132 (62%), Gaps = 2/132 (1%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FGLAK D THV+T V GT G+ APEY+ TG + K+DV+ +GV+LLE+++G+R+ D Sbjct: 435 FGLAKLMDYKD-THVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGVMLLELITGQRAFD 493 Query: 252 KNRPNGEHN--LVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKA 425 R + + L++W + LL E+ + LVD L+GN+ + ++ Q+A C P Sbjct: 494 LARLANDDDVMLLDWVKGLLKEK-KLEALVDVDLQGNYKDEEVEQLIQVALLCTQSSPME 552 Query: 426 RPLMSQVVEALK 461 RP MS+VV L+ Sbjct: 553 RPKMSEVVRMLE 564 Score = 21.2 bits (43), Expect(2) = 8e-20 Identities = 8/13 (61%), Positives = 11/13 (84%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 +I+RD K +NILL Sbjct: 412 IIHRDVKAANILL 424
>PSKR_DAUCA (Q8LPB4) Phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1021 Score = 89.4 bits (220), Expect(2) = 1e-18 Identities = 47/118 (39%), Positives = 67/118 (56%) Frame = +3 Query: 108 THVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVE 287 THV+T ++GT GY PEY T K DVYSFGVVLLE+++GRR MD +P G +L+ Sbjct: 899 THVTTDLVGTLGYIPPEYGQASVATYKGDVYSFGVVLLELLTGRRPMDVCKPRGSRDLIS 958 Query: 288 WARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARPLMSQVVEALK 461 W + E+ R ++ DP + + ++A CL +PK RP Q+V L+ Sbjct: 959 WVLQMKTEK-RESEIFDPFIYDKDHAEEMLLVLEIACRCLGENPKTRPTTQQLVSWLE 1015 Score = 22.7 bits (47), Expect(2) = 1e-18 Identities = 12/32 (37%), Positives = 19/32 (59%) Frame = +1 Query: 1 VIYRDFKTSNILLXFGIQCKALXILGLPKMVL 96 +++RD K+SNILL L GL +++L Sbjct: 865 ILHRDIKSSNILLSDTFVAH-LADFGLARLIL 895
>PSKR_ARATH (Q9ZVR7) Putative phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1008 Score = 87.0 bits (214), Expect(2) = 7e-18 Identities = 47/118 (39%), Positives = 68/118 (57%) Frame = +3 Query: 105 KTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLV 284 +THVST ++GT GY PEY T K DVYSFGVVLLE+++ +R +D +P G +L+ Sbjct: 889 ETHVSTDLVGTLGYIPPEYGQASVATYKGDVYSFGVVLLELLTDKRPVDMCKPKGCRDLI 948 Query: 285 EWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARPLMSQVVEAL 458 W + E R ++ DP + + K + ++A CLS +PK RP Q+V L Sbjct: 949 SWVVKMKHE-SRASEVFDPLIYSKENDKEMFRVLEIACLCLSENPKQRPTTQQLVSWL 1005 Score = 22.3 bits (46), Expect(2) = 7e-18 Identities = 8/13 (61%), Positives = 12/13 (92%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 +++RD K+SNILL Sbjct: 856 ILHRDIKSSNILL 868
>SIRK_ARATH (O64483) Senescence-induced receptor-like serine/threonine-protein| kinase precursor (FLG22-induced receptor-like kinase 1) Length = 876 Score = 81.3 bits (199), Expect(2) = 3e-16 Identities = 49/132 (37%), Positives = 71/132 (53%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FGL++ V +ST V G+ GY PEY T + KSDVYS GVVLLE+++G+ ++ Sbjct: 716 FGLSRSFSVEGSGQISTVVAGSIGYLDPEYYSTRQMNEKSDVYSLGVVLLEVITGQPAIA 775 Query: 252 KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 ++ H + + R +L +VD RL + V A K +++A AC RP Sbjct: 776 SSKTEKVH-ISDHVRSILANGD-IRGIVDQRLRERYDVGSAWKMSEIALACTEHTSAQRP 833 Query: 432 LMSQVVEALKPL 467 MSQVV LK + Sbjct: 834 TMSQVVMELKQI 845 Score = 22.7 bits (47), Expect(2) = 3e-16 Identities = 9/20 (45%), Positives = 14/20 (70%) Frame = +1 Query: 1 VIYRDFKTSNILLXFGIQCK 60 +++RD K +NILL +Q K Sbjct: 693 IVHRDVKPTNILLNEKLQAK 712
>EXS_ARATH (Q9LYN8) Leucine-rich repeat receptor protein kinase EXS precursor| (EC 2.7.11.1) (Extra sporogenous cells protein) (EXCESS MICROSPOROCYTES1 protein) Length = 1192 Score = 80.5 bits (197), Expect(2) = 4e-16 Identities = 47/123 (38%), Positives = 74/123 (60%), Gaps = 2/123 (1%) Frame = +3 Query: 105 KTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGE-HNL 281 ++HVST + GT+GY PEY + T+K DVYSFGV+LLE+++G+ + E NL Sbjct: 1072 ESHVSTVIAGTFGYIPPEYGQSARATTKGDVYSFGVILLELVTGKEPTGPDFKESEGGNL 1131 Query: 282 VEWARPLLGERQRFYKLVDPRLEGNFSVKGAQ-KAAQLARACLSRDPKARPLMSQVVEAL 458 V WA + + + ++DP L + ++K +Q + Q+A CL+ P RP M V++AL Sbjct: 1132 VGWAIQKINQ-GKAVDVIDPLLV-SVALKNSQLRLLQIAMLCLAETPAKRPNMLDVLKAL 1189 Query: 459 KPL 467 K + Sbjct: 1190 KEI 1192 Score = 23.1 bits (48), Expect(2) = 4e-16 Identities = 12/31 (38%), Positives = 19/31 (61%) Frame = +1 Query: 1 VIYRDFKTSNILLXFGIQCKALXILGLPKMV 93 +I+RD K SNILL + K + GL +++ Sbjct: 1039 IIHRDIKASNILLDGDFEPK-VADFGLARLI 1068
>BRL3_ARATH (Q9LJF3) Serine/threonine-protein kinase BRI1-like 3 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 3) Length = 1164 Score = 78.2 bits (191), Expect(2) = 2e-15 Identities = 52/137 (37%), Positives = 76/137 (55%), Gaps = 5/137 (3%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVM-GTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSM 248 FG+A+ D TH+S + GT GY PEY + T+K DVYS+GV+LLE++SG++ + Sbjct: 1004 FGMARLVSALD-THLSVSTLAGTPGYVPPEYYQSFRCTAKGDVYSYGVILLELLSGKKPI 1062 Query: 249 DKNRPNGEHNLVEWARPLLGERQRFYKLVDPRL----EGNFSVKGAQKAAQLARACLSRD 416 D ++NLV WA+ L E+ R +++DP L G+ + K +A CL Sbjct: 1063 DPEEFGEDNNLVGWAKQLYREK-RGAEILDPELVTDKSGDVELLHYLK---IASQCLDDR 1118 Query: 417 PKARPLMSQVVEALKPL 467 P RP M QV+ K L Sbjct: 1119 PFKRPTMIQVMTMFKEL 1135 Score = 22.7 bits (47), Expect(2) = 2e-15 Identities = 8/13 (61%), Positives = 12/13 (92%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 +I+RD K+SN+LL Sbjct: 981 IIHRDMKSSNVLL 993
>BRL1_ARATH (Q9ZWC8) Serine/threonine-protein kinase BRI1-like 1 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 1) Length = 1166 Score = 75.9 bits (185), Expect(2) = 1e-14 Identities = 50/137 (36%), Positives = 76/137 (55%), Gaps = 5/137 (3%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVM-GTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSM 248 FG+A+ D TH+S + GT GY PEY + T+K DVYS+GV+LLE++SG++ + Sbjct: 1006 FGMARLVSALD-THLSVSTLAGTPGYVPPEYYQSFRCTAKGDVYSYGVILLELLSGKKPI 1064 Query: 249 DKNRPNGEHNLVEWARPLLGERQRFYKLVDPRL----EGNFSVKGAQKAAQLARACLSRD 416 D ++NLV WA+ L E+ R +++DP L G+ + K +A CL Sbjct: 1065 DPGEFGEDNNLVGWAKQLYREK-RGAEILDPELVTDKSGDVELFHYLK---IASQCLDDR 1120 Query: 417 PKARPLMSQVVEALKPL 467 P RP M Q++ K + Sbjct: 1121 PFKRPTMIQLMAMFKEM 1137 Score = 22.7 bits (47), Expect(2) = 1e-14 Identities = 8/13 (61%), Positives = 12/13 (92%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 +I+RD K+SN+LL Sbjct: 983 IIHRDMKSSNVLL 995
>RLK5_ARATH (P47735) Receptor-like protein kinase 5 precursor (EC 2.7.11.1)| Length = 999 Score = 74.7 bits (182), Expect(2) = 3e-14 Identities = 48/135 (35%), Positives = 76/135 (56%), Gaps = 2/135 (1%) Frame = +3 Query: 72 FGLAKDGPV-GDKT-HVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRS 245 FG+AK G + G KT + + G+ GY APEYV T + KSD+YSFGVVLLE+++G++ Sbjct: 838 FGIAKVGQMSGSKTPEAMSGIAGSCGYIAPEYVYTLRVNEKSDIYSFGVVLLELVTGKQP 897 Query: 246 MDKNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKA 425 D G+ ++ +W L ++ ++DP+L+ F + K + C S P Sbjct: 898 TDSEL--GDKDMAKWVCTAL-DKCGLEPVIDPKLDLKFK-EEISKVIHIGLLCTSPLPLN 953 Query: 426 RPLMSQVVEALKPLA 470 RP M +VV L+ ++ Sbjct: 954 RPSMRKVVIMLQEVS 968 Score = 22.3 bits (46), Expect(2) = 3e-14 Identities = 8/13 (61%), Positives = 12/13 (92%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 +++RD K+SNILL Sbjct: 815 IVHRDVKSSNILL 827
>CLV1_ARATH (Q9SYQ8) Receptor protein kinase CLAVATA1 precursor (EC 2.7.11.1)| Length = 980 Score = 75.9 bits (185), Expect(2) = 4e-14 Identities = 51/139 (36%), Positives = 72/139 (51%), Gaps = 10/139 (7%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FGLAK G + + + G+YGY APEY T + KSDVYSFGVVLLE+++G+ Sbjct: 836 FGLAKFLVDGAASECMSSIAGSYGYIAPEYAYTLKVDEKSDVYSFGVVLLELIAGK---- 891 Query: 252 KNRPNGEH----NLVEWARPLLGERQR------FYKLVDPRLEGNFSVKGAQKAAQLARA 401 +P GE ++V W R E + +VDPRL G + + ++A Sbjct: 892 --KPVGEFGEGVDIVRWVRNTEEEITQPSDAAIVVAIVDPRLTG-YPLTSVIHVFKIAMM 948 Query: 402 CLSRDPKARPLMSQVVEAL 458 C+ + ARP M +VV L Sbjct: 949 CVEEEAAARPTMREVVHML 967 Score = 20.8 bits (42), Expect(2) = 4e-14 Identities = 7/13 (53%), Positives = 12/13 (92%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 +++RD K++NILL Sbjct: 813 ILHRDVKSNNILL 825
>BRL2_ARATH (Q9ZPS9) Serine/threonine-protein kinase BRI1-like 2 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 2) (Protein VASCULAR HIGHWAY 1) Length = 1143 Score = 73.6 bits (179), Expect(2) = 5e-14 Identities = 52/148 (35%), Positives = 76/148 (51%), Gaps = 16/148 (10%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVM-GTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSM 248 FG+A+ D TH+S + GT GY PEY + T+K DVYS GVV+LE++SG+R Sbjct: 985 FGMARLISALD-THLSVSTLAGTPGYVPPEYYQSFRCTAKGDVYSIGVVMLEILSGKRPT 1043 Query: 249 DKNRPNGEHNLVEWARPLLGERQRFYKLVDPRL---------------EGNFSVKGAQKA 383 DK G+ NLV W++ + + +++D L EG VK + Sbjct: 1044 DKEE-FGDTNLVGWSK-MKAREGKHMEVIDEDLLKEGSSESLNEKEGFEGGVIVKEMLRY 1101 Query: 384 AQLARACLSRDPKARPLMSQVVEALKPL 467 ++A C+ P RP M QVV +L+ L Sbjct: 1102 LEIALRCVDDFPSKRPNMLQVVASLREL 1129 Score = 22.7 bits (47), Expect(2) = 5e-14 Identities = 8/13 (61%), Positives = 12/13 (92%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 +I+RD K+SN+LL Sbjct: 962 IIHRDMKSSNVLL 974
>RPK1_IPONI (P93194) Receptor-like protein kinase precursor (EC 2.7.11.1)| Length = 1109 Score = 74.3 bits (181), Expect = 2e-13 Identities = 47/133 (35%), Positives = 72/133 (54%), Gaps = 4/133 (3%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FG+AK + S V GT GY APE T + +SDVYS+GVVLLE+++ ++++D Sbjct: 961 FGIAKLLDQSATSIPSNTVQGTIGYMAPENAFTTVKSRESDVYSYGVVLLELITRKKALD 1020 Query: 252 KNRPNGEHNLVEWARPLLGERQRFYKLVDP----RLEGNFSVKGAQKAAQLARACLSRDP 419 + NGE ++V W R + + K+VDP L + ++ +A LA C ++ Sbjct: 1021 PSF-NGETDIVGWVRSVWTQTGEIQKIVDPSLLDELIDSSVMEQVTEALSLALRCAEKEV 1079 Query: 420 KARPLMSQVVEAL 458 RP M VV+ L Sbjct: 1080 DKRPTMRDVVKQL 1092
>SRK6_BRAOE (Q09092) Putative serine/threonine-protein kinase receptor precursor| (EC 2.7.11.1) (S-receptor kinase) (SRK) Length = 849 Score = 71.6 bits (174), Expect(2) = 2e-13 Identities = 48/145 (33%), Positives = 80/145 (55%), Gaps = 10/145 (6%) Frame = +3 Query: 45 RNTMQSSQXFGLAKDGPVGDKTHVST-RVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLL 221 +N + FG+A+ D+T +T +V+GTYGY +PEY M G + KSDV+SFGV++L Sbjct: 663 KNMIPKISDFGMARIFE-RDETEANTMKVVGTYGYMSPEYAMYGIFSEKSDVFSFGVIVL 721 Query: 222 EMMSGRRSMDKNRPNGEHNLVE--WARPLLGERQRFYKLVDPRLEGN-------FSVKGA 374 E++SG+++ + E++L+ W+R + R ++VDP + + F + Sbjct: 722 EIVSGKKNRGFYNLDYENDLLSYVWSR---WKEGRALEIVDPVIVDSLSSQPSIFQPQEV 778 Query: 375 QKAAQLARACLSRDPKARPLMSQVV 449 K Q+ C+ + RP MS VV Sbjct: 779 LKCIQIGLLCVQELAEHRPAMSSVV 803 Score = 22.7 bits (47), Expect(2) = 2e-13 Identities = 9/13 (69%), Positives = 11/13 (84%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 +I+RD K SNILL Sbjct: 649 IIHRDLKVSNILL 661
>BRI1_ARATH (O22476) BRASSINOSTEROID INSENSITIVE 1 precursor (EC 2.7.11.1)| (AtBRI1) (Brassinosteroid LRR receptor kinase) Length = 1196 Score = 65.1 bits (157), Expect(2) = 9e-12 Identities = 47/135 (34%), Positives = 71/135 (52%), Gaps = 3/135 (2%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVM-GTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSM 248 FG+A+ D TH+S + GT GY PEY + ++K DVYS+GVVLLE+++G+R Sbjct: 1028 FGMARLMSAMD-THLSVSTLAGTPGYVPPEYYQSFRCSTKGDVYSYGVVLLELLTGKRPT 1086 Query: 249 DKNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQ--KAAQLARACLSRDPK 422 D + G++NLV W + + R + DP L + + ++A ACL Sbjct: 1087 D-SPDFGDNNLVGWVKQ--HAKLRISDVFDPELMKEDPALEIELLQHLKVAVACLDDRAW 1143 Query: 423 ARPLMSQVVEALKPL 467 RP M QV+ K + Sbjct: 1144 RRPTMVQVMAMFKEI 1158 Score = 23.5 bits (49), Expect(2) = 9e-12 Identities = 8/20 (40%), Positives = 15/20 (75%) Frame = +1 Query: 1 VIYRDFKTSNILLXFGIQCK 60 +I+RD K+SN+LL ++ + Sbjct: 1005 IIHRDMKSSNVLLDENLEAR 1024
>KPRO_MAIZE (P17801) Putative receptor protein kinase ZmPK1 precursor (EC| 2.7.11.1) Length = 817 Score = 67.4 bits (163), Expect = 2e-11 Identities = 48/136 (35%), Positives = 70/136 (51%), Gaps = 7/136 (5%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FGL K G T + V GT GY APE+V + +T+K DVYS+GVVLLE+++G R + Sbjct: 677 FGLVKLLNRGGSTQNVSHVRGTLGYIAPEWVSSLPITAKVDVYSYGVVLLELLTGTRVSE 736 Query: 252 KNRPNGE-HNLVE-----WARPLLGERQRFYK-LVDPRLEGNFSVKGAQKAAQLARACLS 410 E H+++ + L GE Q + +D +L + A+ +LA +CL Sbjct: 737 LVGGTDEVHSMLRKLVRMLSAKLEGEEQSWIDGYLDSKLNRPVNYVQARTLIKLAVSCLE 796 Query: 411 RDPKARPLMSQVVEAL 458 D RP M V+ L Sbjct: 797 EDRSKRPTMEHAVQTL 812
>BRI1_LYCPE (Q8L899) Systemin receptor SR160 precursor (EC 2.7.11.1)| (Brassinosteroid LRR receptor kinase) Length = 1207 Score = 62.8 bits (151), Expect(2) = 5e-11 Identities = 46/136 (33%), Positives = 74/136 (54%), Gaps = 4/136 (2%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVM-GTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSM 248 FG+A+ D TH+S + GT GY PEY + ++K DVYS+GVVLLE+++G++ Sbjct: 1033 FGMARLMSAMD-THLSVSTLAGTPGYVPPEYYQSFRCSTKGDVYSYGVVLLELLTGKQPT 1091 Query: 249 DKNRPNGEHNLVEWARPLLGERQRFYKLVDPRL---EGNFSVKGAQKAAQLARACLSRDP 419 D + G++NLV W + L + + + D L + + ++ Q ++A ACL Sbjct: 1092 D-SADFGDNNLVGWVK--LHAKGKITDVFDRELLKEDASIEIELLQH-LKVACACLDDRH 1147 Query: 420 KARPLMSQVVEALKPL 467 RP M QV+ K + Sbjct: 1148 WKRPTMIQVMAMFKEI 1163 Score = 23.5 bits (49), Expect(2) = 5e-11 Identities = 8/20 (40%), Positives = 15/20 (75%) Frame = +1 Query: 1 VIYRDFKTSNILLXFGIQCK 60 +I+RD K+SN+LL ++ + Sbjct: 1010 IIHRDMKSSNVLLDENLEAR 1029
>BRI1_LYCES (Q8GUQ5) Brassinosteroid LRR receptor kinase precursor (EC 2.7.11.1)| (tBRI1) (Altered brassinolide sensitivity 1) (Systemin receptor SR160) Length = 1207 Score = 62.8 bits (151), Expect(2) = 5e-11 Identities = 46/136 (33%), Positives = 74/136 (54%), Gaps = 4/136 (2%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVM-GTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSM 248 FG+A+ D TH+S + GT GY PEY + ++K DVYS+GVVLLE+++G++ Sbjct: 1033 FGMARLMSAMD-THLSVSTLAGTPGYVPPEYYQSFRCSTKGDVYSYGVVLLELLTGKQPT 1091 Query: 249 DKNRPNGEHNLVEWARPLLGERQRFYKLVDPRL---EGNFSVKGAQKAAQLARACLSRDP 419 D + G++NLV W + L + + + D L + + ++ Q ++A ACL Sbjct: 1092 D-SADFGDNNLVGWVK--LHAKGKITDVFDRELLKEDASIEIELLQH-LKVACACLDDRH 1147 Query: 420 KARPLMSQVVEALKPL 467 RP M QV+ K + Sbjct: 1148 WKRPTMIQVMAMFKEI 1163 Score = 23.5 bits (49), Expect(2) = 5e-11 Identities = 8/20 (40%), Positives = 15/20 (75%) Frame = +1 Query: 1 VIYRDFKTSNILLXFGIQCK 60 +I+RD K+SN+LL ++ + Sbjct: 1010 IIHRDMKSSNVLLDENLEAR 1029
>IRAK4_HUMAN (Q9NWZ3) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) (NY-REN-64 antigen) Length = 460 Score = 62.8 bits (151), Expect(2) = 3e-10 Identities = 40/132 (30%), Positives = 71/132 (53%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FGLA+ +T +++R++GT Y APE + G +T KSD+YSFGVVLLE+++G ++D Sbjct: 330 FGLARASEKFAQTVMTSRIVGTTAYMAPE-ALRGEITPKSDIYSFGVVLLEIITGLPAVD 388 Query: 252 KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 ++R L++ + E + +D ++ S + +A CL RP Sbjct: 389 EHRE--PQLLLDIKEEIEDEEKTIEDYIDKKMNDADST-SVEAMYSVASQCLHEKKNKRP 445 Query: 432 LMSQVVEALKPL 467 + +V + L+ + Sbjct: 446 DIKKVQQLLQEM 457 Score = 20.8 bits (42), Expect(2) = 3e-10 Identities = 8/12 (66%), Positives = 11/12 (91%) Frame = +1 Query: 4 IYRDFKTSNILL 39 I+RD K++NILL Sbjct: 308 IHRDIKSANILL 319
>IRAK4_MOUSE (Q8R4K2) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) Length = 459 Score = 62.8 bits (151), Expect(2) = 3e-10 Identities = 40/133 (30%), Positives = 71/133 (53%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FGLA+ +T +++R++GT Y APE + G +T KSD+YSFGVVLLE+++G ++D Sbjct: 330 FGLARASARLAQTVMTSRIVGTTAYMAPE-ALRGEITPKSDIYSFGVVLLELITGLAAVD 388 Query: 252 KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 +NR L++ + E + D ++ + + A CL RP Sbjct: 389 ENRE--PQLLLDIKEEIEDEEKTIEDYTDEKM-SDADPASVEAMYSAASQCLHEKKNRRP 445 Query: 432 LMSQVVEALKPLA 470 +++V + L+ ++ Sbjct: 446 DIAKVQQLLQEMS 458 Score = 20.8 bits (42), Expect(2) = 3e-10 Identities = 8/12 (66%), Positives = 11/12 (91%) Frame = +1 Query: 4 IYRDFKTSNILL 39 I+RD K++NILL Sbjct: 308 IHRDIKSANILL 319
>KPEL_DROME (Q05652) Probable serine/threonine-protein kinase pelle (EC| 2.7.11.1) Length = 501 Score = 58.5 bits (140), Expect = 1e-08 Identities = 42/135 (31%), Positives = 69/135 (51%), Gaps = 4/135 (2%) Frame = +3 Query: 72 FGLAKDGPVG-DKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSM 248 FGL ++GP D +V GT Y PE+ L++ DVYSFG+VLLE+ +GR+ Sbjct: 365 FGLVREGPKSLDAVVEVNKVFGTKIYLPPEFRNFRQLSTGVDVYSFGIVLLEVFTGRQVT 424 Query: 249 DKNRPN-GEHNLVEWARPLLGERQRFYKLVDPRLEGNF--SVKGAQKAAQLARACLSRDP 419 D+ N + NL+++ + RQ +L++ L + A + C + DP Sbjct: 425 DRVPENETKKNLLDYVKQQW--RQNRMELLEKHLAAPMGKELDMCMCAIEAGLHCTALDP 482 Query: 420 KARPLMSQVVEALKP 464 + RP M+ V++ +P Sbjct: 483 QDRPSMNAVLKRFEP 497
>IRAK1_HUMAN (P51617) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) Length = 712 Score = 58.5 bits (140), Expect = 1e-08 Identities = 50/159 (31%), Positives = 71/159 (44%), Gaps = 31/159 (19%) Frame = +3 Query: 126 VMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEH--NLVE---- 287 V GT Y EY+ TG L +D +SFGVV+LE ++G+R++ + ++ +LVE Sbjct: 384 VRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAE 443 Query: 288 ---------------------WARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARAC 404 WA P+ Q + K +DPR G + QLA C Sbjct: 444 EAGVALRSTQSTLQAGLAADAWAAPI--AMQIYKKHLDPR-PGPCPPELGLGLGQLACCC 500 Query: 405 LSRDPKARPLMSQVVEALKPL----A*PQGHGQLLVLLP 509 L R K RP M+QV E L+ L A GH + +P Sbjct: 501 LHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIP 539
>IRAK1_MOUSE (Q62406) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK) Length = 710 Score = 53.9 bits (128), Expect = 2e-07 Identities = 43/144 (29%), Positives = 66/144 (45%), Gaps = 27/144 (18%) Frame = +3 Query: 117 STRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEH--NLVE- 287 ++ V GT Y EY+ TG L +D +SFGVV+LE ++G+R++ ++ +L+E Sbjct: 381 TSTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVILETLAGQRAVRTQGAKTKYLKDLIED 440 Query: 288 ------------------------WARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLA 395 WA P+ Q + K +D R G + AQLA Sbjct: 441 EAEEAGVTLKSTQPTLWVGVATDAWAAPIAA--QIYKKHLDSR-PGPCPPQLGLALAQLA 497 Query: 396 RACLSRDPKARPLMSQVVEALKPL 467 C+ R K RP M+QV + L+ L Sbjct: 498 CCCMHRRAKKRPPMTQVYKRLEGL 521
>PKN5_MYXXA (P54737) Serine/threonine-protein kinase pkn5 (EC 2.7.11.1)| Length = 380 Score = 50.4 bits (119), Expect = 3e-06 Identities = 40/130 (30%), Positives = 62/130 (47%), Gaps = 1/130 (0%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FGLAK + +++GTY Y APE ++ L ++D+YS GV+L E++SGR D Sbjct: 263 FGLAKFLADDAAITEAGKLVGTYRYMAPEQILGEPLDGRADLYSLGVILYELLSGRPPFD 322 Query: 252 KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKAR- 428 P H L W + L E L ++ G + A++A + ++P R Sbjct: 323 AKTP---HEL--WRQVLETEPPPVLAL---------NLHGDPQLARVAHRLIRKEPDDRF 368 Query: 429 PLMSQVVEAL 458 +V EAL Sbjct: 369 QTAEEVYEAL 378
>SPKA_SYNY3 (Q9FAB3) Serine/threonine-protein kinase A (EC 2.7.11.1)| Length = 521 Score = 45.4 bits (106), Expect(2) = 2e-05 Identities = 33/128 (25%), Positives = 56/128 (43%), Gaps = 2/128 (1%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSM- 248 FG+AK +++ MGT Y +PE + L S+SD+YS GV++ EM++G + Sbjct: 171 FGIAKLVQAAEESKTQA-FMGTLAYCSPEQMEGKELDSRSDIYSLGVMMYEMLTGEMPLF 229 Query: 249 -DKNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKA 425 D + G + +P + + + +A L CL++ PK Sbjct: 230 PDNSSFGGWYEAHHHTKP-------------HPFSARYKIPASLEA--LVMNCLAKSPKG 274 Query: 426 RPLMSQVV 449 RP V+ Sbjct: 275 RPQSVDVI 282 Score = 21.9 bits (45), Expect(2) = 2e-05 Identities = 8/13 (61%), Positives = 11/13 (84%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 V++RD K SN+LL Sbjct: 144 VVHRDIKPSNVLL 156
>M3LK7_DROME (P83104) Putative mitogen-activated protein kinase kinase kinase| 7-like (EC 2.7.11.25) Length = 393 Score = 46.2 bits (108), Expect = 5e-05 Identities = 37/130 (28%), Positives = 60/130 (46%), Gaps = 1/130 (0%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FGLA D ++ T + GT Y APE + T+K DVYSFG++L E+M+ + Sbjct: 153 FGLATD-----MSNNKTDMQGTLRYMAPEAIKHLKYTAKCDVYSFGIMLWELMTRQLPYS 207 Query: 252 K-NRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKAR 428 PN ++ +++ GE+ + EG QL C+ +P+ R Sbjct: 208 HLENPNSQYAIMKAISS--GEKLPMEAVRSDCPEG---------IKQLMECCMDINPEKR 256 Query: 429 PLMSQVVEAL 458 P M ++ + L Sbjct: 257 PSMKEIEKFL 266
>IRAK3_MOUSE (Q8K4B2) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 609 Score = 45.8 bits (107), Expect = 7e-05 Identities = 34/109 (31%), Positives = 53/109 (48%), Gaps = 3/109 (2%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSM--DKNRPNGEHNLVE-WARPLLGER 314 Y EY+ G L+ K+DVYSFG+V++E+++G + + D L+E + L Sbjct: 353 YMPEEYIRQGRLSVKTDVYSFGIVIMEVLTGCKVVLDDPKHVQLRDLLMELMEKRGLDSC 412 Query: 315 QRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARPLMSQVVEALK 461 F P NFS K LA C++ K RP M +V+ +L+ Sbjct: 413 LSFLDRKIPPCPRNFSA----KLFSLAGRCVATKAKLRPTMDEVLSSLE 457
>YES_XENLA (P10936) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 536 Score = 42.0 bits (97), Expect(2) = 7e-05 Identities = 28/106 (26%), Positives = 49/106 (46%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLLGERQRF 323 + APE + G T KSDV+SFG++L E+++ R N R +L + +R Sbjct: 431 WTAPEAALYGRFTIKSDVWSFGILLTELVAKGRVPYPGMVN---------REVLEQVERG 481 Query: 324 YKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARPLMSQVVEALK 461 Y++ P+ + + +L + C +DP RP + L+ Sbjct: 482 YRMPCPQ-------RCPESLHELMKLCWKKDPDERPTFEYIQSFLE 520 Score = 23.1 bits (48), Expect(2) = 7e-05 Identities = 10/30 (33%), Positives = 19/30 (63%) Frame = +1 Query: 4 IYRDFKTSNILLXFGIQCKALXILGLPKMV 93 I+RD + +NIL+ + CK + GL +++ Sbjct: 386 IHRDLRAANILVGDNLVCK-IADFGLARLI 414
>KPCI_PONPY (Q5R4K9) Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota)| Length = 587 Score = 42.4 bits (98), Expect(2) = 9e-05 Identities = 36/122 (29%), Positives = 60/122 (49%), Gaps = 3/122 (2%) Frame = +3 Query: 72 FGLAKDG-PVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSM 248 +G+ K+G GD T + GT Y APE + D ++ GV++ EMM+GR Sbjct: 388 YGMCKEGLRPGDTT---STFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPF 444 Query: 249 D--KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPK 422 D + N + N ++ ++ E+Q R+ + SV KAA + ++ L++DPK Sbjct: 445 DIVGSSDNPDQNTEDYLFQVILEKQ-------IRIPRSLSV----KAASVLKSFLNKDPK 493 Query: 423 AR 428 R Sbjct: 494 ER 495 Score = 22.3 bits (46), Expect(2) = 9e-05 Identities = 8/13 (61%), Positives = 10/13 (76%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 +IYRD K N+LL Sbjct: 365 IIYRDLKLDNVLL 377
>KPCI_HUMAN (P41743) Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota)| (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (PRKC-lambda/iota) Length = 587 Score = 42.4 bits (98), Expect(2) = 9e-05 Identities = 36/122 (29%), Positives = 60/122 (49%), Gaps = 3/122 (2%) Frame = +3 Query: 72 FGLAKDG-PVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSM 248 +G+ K+G GD T + GT Y APE + D ++ GV++ EMM+GR Sbjct: 388 YGMCKEGLRPGDTT---STFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPF 444 Query: 249 D--KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPK 422 D + N + N ++ ++ E+Q R+ + SV KAA + ++ L++DPK Sbjct: 445 DIVGSSDNPDQNTEDYLFQVILEKQ-------IRIPRSLSV----KAASVLKSFLNKDPK 493 Query: 423 AR 428 R Sbjct: 494 ER 495 Score = 22.3 bits (46), Expect(2) = 9e-05 Identities = 8/13 (61%), Positives = 10/13 (76%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 +IYRD K N+LL Sbjct: 365 IIYRDLKLDNVLL 377
>KPCI_MOUSE (Q62074) Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota)| (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) Length = 586 Score = 42.4 bits (98), Expect(2) = 9e-05 Identities = 36/122 (29%), Positives = 60/122 (49%), Gaps = 3/122 (2%) Frame = +3 Query: 72 FGLAKDG-PVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSM 248 +G+ K+G GD T + GT Y APE + D ++ GV++ EMM+GR Sbjct: 387 YGMCKEGLRPGDTT---STFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPF 443 Query: 249 D--KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPK 422 D + N + N ++ ++ E+Q R+ + SV KAA + ++ L++DPK Sbjct: 444 DIVGSSDNPDQNTEDYLFQVILEKQ-------IRIPRSLSV----KAASVLKSFLNKDPK 492 Query: 423 AR 428 R Sbjct: 493 ER 494 Score = 22.3 bits (46), Expect(2) = 9e-05 Identities = 8/13 (61%), Positives = 10/13 (76%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 +IYRD K N+LL Sbjct: 364 IIYRDLKLDNVLL 376
>SRC_RSVSE (P63185) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 42.4 bits (98), Expect(2) = 9e-05 Identities = 31/107 (28%), Positives = 46/107 (42%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLLGERQRF 323 + APE + G T KSDV+SFG++L E+ + R NGE +L +R Sbjct: 427 WTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMGNGE---------VLDRVERG 477 Query: 324 YKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARPLMSQVVEALKP 464 Y++ P + + L C RDP+ RP + L P Sbjct: 478 YRMPCP-------PECPESLHDLMSQCWRRDPEERPTFEYLQAQLLP 517 Score = 22.3 bits (46), Expect(2) = 9e-05 Identities = 9/30 (30%), Positives = 19/30 (63%) Frame = +1 Query: 4 IYRDFKTSNILLXFGIQCKALXILGLPKMV 93 ++RD + +NIL+ + CK + GL +++ Sbjct: 382 VHRDLRAANILVGENLVCK-VADFGLARLI 410
>PTK6_MOUSE (Q64434) Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related| intestinal kinase) Length = 451 Score = 45.1 bits (105), Expect = 1e-04 Identities = 38/129 (29%), Positives = 57/129 (44%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FGLA+ V + ++S Y + APE + GH + KSDV+SFGV+L E+ S Sbjct: 331 FGLAR--LVKEDIYLSHEHNVPYKWTAPEALSRGHYSIKSDVWSFGVLLHEIFSRG---- 384 Query: 252 KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 + P + + F + VD ++ +L +C SRDPK RP Sbjct: 385 -----------QMPYPGMSNHETFLR-VDAGYRMPCPLECPPNIHKLMLSCWSRDPKQRP 432 Query: 432 LMSQVVEAL 458 + E L Sbjct: 433 CFKDLCEKL 441
>HT1_ARATH (Q2MHE4) Serine/threonine-protein kinase HT1 (EC 2.7.11.1) (High| leaf temperature protein 1) Length = 390 Score = 42.7 bits (99), Expect(2) = 1e-04 Identities = 34/111 (30%), Positives = 48/111 (43%) Frame = +3 Query: 129 MGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLLG 308 MGTY + APE + T K DVYSFG+VL E+ + P V+ A + Sbjct: 247 MGTYRWMAPEMIKEKPYTRKVDVYSFGIVLWELTTALLPFQGMTP------VQAAFAVAE 300 Query: 309 ERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARPLMSQVVEALK 461 + +R P L + A L + C S +P RP S +V L+ Sbjct: 301 KNER------PPLPASCQ----PALAHLIKRCWSENPSKRPDFSNIVAVLE 341 Score = 21.6 bits (44), Expect(2) = 1e-04 Identities = 8/13 (61%), Positives = 12/13 (92%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 VI+RD K++N+LL Sbjct: 208 VIHRDLKSNNLLL 220
>PKN2_CORGL (Q8NU97) Serine/threonine protein kinases pknA (EC 2.7.11.1)| Length = 469 Score = 44.7 bits (104), Expect = 1e-04 Identities = 25/57 (43%), Positives = 32/57 (56%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRR 242 FG+AK T V+GT Y +PE +T+ SD+YS GVV EMM+GRR Sbjct: 167 FGIAKAAAAVPLTRTGM-VVGTAQYVSPEQAQGKEVTAASDIYSLGVVGYEMMAGRR 222
>PK1_STRTO (Q9KIG4) Serine/threonine-protein kinase PK-1 (EC 2.7.11.1)| (stoPK-1) Length = 641 Score = 44.7 bits (104), Expect = 1e-04 Identities = 23/64 (35%), Positives = 36/64 (56%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FGL + V T+ + V+GT Y APE + G + DVY+ G++L EM++G + D Sbjct: 160 FGLVR--AVDSVTNTTGTVLGTVSYLAPEQIEHGTADPRVDVYACGILLYEMLTGEKPHD 217 Query: 252 KNRP 263 + P Sbjct: 218 GDSP 221
>IRAK3_HUMAN (Q9Y616) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 596 Score = 44.7 bits (104), Expect = 1e-04 Identities = 36/112 (32%), Positives = 55/112 (49%), Gaps = 6/112 (5%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEH-NLVEWARPLLGER-- 314 Y EY+ G L+ K+DVYSFG+V++E+++G R + + +H L + R L+ +R Sbjct: 340 YMPEEYIRQGKLSIKTDVYSFGIVIMEVLTGCRVV---LDDPKHIQLRDLLRELMEKRGL 396 Query: 315 ---QRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARPLMSQVVEALK 461 F P NFS K LA C + K RP M +V+ L+ Sbjct: 397 DSCLSFLDKKVPPCPRNFSA----KLFCLAGRCAATRAKLRPSMDEVLNTLE 444
>SRC_RSVSA (P00524) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 41.6 bits (96), Expect(2) = 2e-04 Identities = 31/107 (28%), Positives = 46/107 (42%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLLGERQRF 323 + APE + G T KSDV+SFG++L E+ + R NGE +L +R Sbjct: 427 WTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMGNGE---------VLDRVERG 477 Query: 324 YKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARPLMSQVVEALKP 464 Y++ P + + L C RDP+ RP + L P Sbjct: 478 YRMPCP-------PECPESLHDLMCQCWRRDPEERPTFEYLQAQLLP 517 Score = 22.3 bits (46), Expect(2) = 2e-04 Identities = 9/30 (30%), Positives = 19/30 (63%) Frame = +1 Query: 4 IYRDFKTSNILLXFGIQCKALXILGLPKMV 93 ++RD + +NIL+ + CK + GL +++ Sbjct: 382 VHRDLRAANILVGENLVCK-VADFGLARLI 410
>SRC_AVISR (P00525) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 41.6 bits (96), Expect(2) = 2e-04 Identities = 31/107 (28%), Positives = 46/107 (42%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLLGERQRF 323 + APE + G T KSDV+SFG++L E+ + R NGE +L +R Sbjct: 427 WTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMGNGE---------VLDRVERG 477 Query: 324 YKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARPLMSQVVEALKP 464 Y++ P + + L C RDP+ RP + L P Sbjct: 478 YRMPCP-------PECPESLHDLMCQCWRRDPEERPTFEYLQAQLLP 517 Score = 22.3 bits (46), Expect(2) = 2e-04 Identities = 9/30 (30%), Positives = 19/30 (63%) Frame = +1 Query: 4 IYRDFKTSNILLXFGIQCKALXILGLPKMV 93 ++RD + +NIL+ + CK + GL +++ Sbjct: 382 VHRDLRAANILVGENLVCK-VADFGLARLI 410
>MOS_XENLA (P12965) Serine/threonine-protein kinase mos (EC 2.7.11.1)| (pp39-mos) Length = 359 Score = 41.6 bits (96), Expect(2) = 2e-04 Identities = 31/112 (27%), Positives = 51/112 (45%) Frame = +3 Query: 126 VMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLL 305 V GTY + APE + +T+K+D+YSF + L +M+S G+ V +A Sbjct: 233 VGGTYTHRAPELLKGEPVTAKADIYSFAITLWQMVSRELPY-----TGDRQCVLYAVVAY 287 Query: 306 GERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARPLMSQVVEALK 461 R L EG + A + ++C + P+ RP Q++E L+ Sbjct: 288 DLRPEMGPLFSHTEEG-------RAARTIVQSCWAARPQERPNAEQLLERLE 332 Score = 22.3 bits (46), Expect(2) = 2e-04 Identities = 9/20 (45%), Positives = 13/20 (65%) Frame = +1 Query: 1 VIYRDFKTSNILLXFGIQCK 60 V++ D K +N+LL G CK Sbjct: 185 VVHLDLKPANVLLAPGDLCK 204
>PKN2_BACSU (O34507) Probable serine/threonine-protein kinase yloP (EC| 2.7.11.1) Length = 648 Score = 44.3 bits (103), Expect = 2e-04 Identities = 23/60 (38%), Positives = 35/60 (58%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FG+A TH ++ V+G+ Y +PE G T KSD+Y+ G+VL E+++GR D Sbjct: 153 FGIATALSSTTITHTNS-VLGSVHYLSPEQARGGLATKKSDIYALGIVLFELLTGRIPFD 211
>VGFR3_RAT (Q91ZT1) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1363 Score = 44.3 bits (103), Expect = 2e-04 Identities = 39/115 (33%), Positives = 53/115 (46%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLLGERQRF 323 + APE + T++SDV+SFGV+L E+ S S P + N R G R R Sbjct: 1080 WMAPESIFDKVYTTQSDVWSFGVLLWEIFSLGAS---PYPGVQINEEFCQRLKDGTRMRA 1136 Query: 324 YKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARPLMSQVVEALKPLA*PQGHG 488 +L P + + ++C S DPKARP S +VE L L QG G Sbjct: 1137 PELATPAIR------------HIMQSCWSGDPKARPAFSDLVEILGDLL--QGGG 1177
>VGFR3_MOUSE (P35917) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1363 Score = 44.3 bits (103), Expect = 2e-04 Identities = 39/115 (33%), Positives = 53/115 (46%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLLGERQRF 323 + APE + T++SDV+SFGV+L E+ S S P + N R G R R Sbjct: 1080 WMAPESIFDKVYTTQSDVWSFGVLLWEIFSLGAS---PYPGVQINEEFCQRLKDGTRMRA 1136 Query: 324 YKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARPLMSQVVEALKPLA*PQGHG 488 +L P + + ++C S DPKARP S +VE L L QG G Sbjct: 1137 PELATPAIR------------HIMQSCWSGDPKARPAFSDLVEILGDLL--QGGG 1177
>STK24_MOUSE (Q99KH8) Serine/threonine-protein kinase 24 (EC 2.7.11.1)| Length = 431 Score = 44.3 bits (103), Expect = 2e-04 Identities = 32/127 (25%), Positives = 55/127 (43%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FG+A G + D +GT + APE + SK+D++S G+ +E+ G Sbjct: 163 FGVA--GQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELAKGEPPHS 220 Query: 252 KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 + P L+ P P LEGN+S + + ACL+++P RP Sbjct: 221 ELHPMKVLFLIPKNNP-------------PTLEGNYS----KPLKEFVEACLNKEPSFRP 263 Query: 432 LMSQVVE 452 ++++ Sbjct: 264 TAKELLK 270
>YES_CHICK (P09324) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 540 Score = 40.4 bits (93), Expect(2) = 2e-04 Identities = 28/106 (26%), Positives = 48/106 (45%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLLGERQRF 323 + APE + G T KSDV+SFG++L E+++ R N R +L + +R Sbjct: 435 WTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMVN---------REVLEQVERG 485 Query: 324 YKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARPLMSQVVEALK 461 Y++ P+ + +L + C +DP RP + L+ Sbjct: 486 YRMPCPQ-------GCPESLHELMKLCWKKDPDERPTFEYIQSFLE 524 Score = 23.1 bits (48), Expect(2) = 2e-04 Identities = 10/30 (33%), Positives = 19/30 (63%) Frame = +1 Query: 4 IYRDFKTSNILLXFGIQCKALXILGLPKMV 93 I+RD + +NIL+ + CK + GL +++ Sbjct: 390 IHRDLRAANILVGDNLVCK-IADFGLARLI 418
>YES_AVISY (P00527) Tyrosine-protein kinase transforming protein YES (EC| 2.7.10.2) (Fragment) Length = 528 Score = 40.4 bits (93), Expect(2) = 2e-04 Identities = 28/106 (26%), Positives = 48/106 (45%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLLGERQRF 323 + APE + G T KSDV+SFG++L E+++ R N R +L + +R Sbjct: 428 WTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMVN---------REVLEQVERG 478 Query: 324 YKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARPLMSQVVEALK 461 Y++ P+ + +L + C +DP RP + L+ Sbjct: 479 YRMPCPQ-------GCPESLHELMKLCWKKDPDERPTFEYIQSFLE 517 Score = 23.1 bits (48), Expect(2) = 2e-04 Identities = 10/30 (33%), Positives = 19/30 (63%) Frame = +1 Query: 4 IYRDFKTSNILLXFGIQCKALXILGLPKMV 93 I+RD + +NIL+ + CK + GL +++ Sbjct: 383 IHRDLRAANILVGDNLVCK-IADFGLARLI 411
>NEK9_XENLA (Q7ZZC8) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)| (NimA-related protein kinase 9) (XNek9) (Nercc1 kinase) Length = 944 Score = 43.9 bits (102), Expect = 3e-04 Identities = 32/132 (24%), Positives = 59/132 (44%), Gaps = 5/132 (3%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 +GLAK + + ++ +GT Y +PE + KSD+++ G VL E+++ R+ D Sbjct: 177 YGLAKQ--LSSEYSMAETCVGTLYYMSPEICQGVKYSFKSDIWAVGCVLYELLTLTRTFD 234 Query: 252 KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSV-----KGAQKAAQLARACLSRD 416 P L ++GN++V Q+ ++ ACL +D Sbjct: 235 ATNP--------------------LNLCVKIVQGNWAVGLDNTVYTQELIEVVHACLEQD 274 Query: 417 PKARPLMSQVVE 452 P+ RP +++E Sbjct: 275 PEKRPTADEILE 286
>VGFR3_HUMAN (P35916) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1298 Score = 43.9 bits (102), Expect = 3e-04 Identities = 39/115 (33%), Positives = 53/115 (46%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLLGERQRF 323 + APE + T++SDV+SFGV+L E+ S S P + N R G R R Sbjct: 1080 WMAPESIFDKVYTTQSDVWSFGVLLWEIFSLGAS---PYPGVQINEEFCQRLRDGTRMRA 1136 Query: 324 YKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARPLMSQVVEALKPLA*PQGHG 488 +L P + ++ C S DPKARP S++VE L L QG G Sbjct: 1137 PELATPAIR------------RIMLNCWSGDPKARPAFSELVEILGDLL--QGRG 1177
>STK24_HUMAN (Q9Y6E0) Serine/threonine-protein kinase 24 (EC 2.7.11.1)| (STE20-like kinase MST3) (MST-3) (Mammalian STE20-like protein kinase 3) Length = 443 Score = 43.9 bits (102), Expect = 3e-04 Identities = 32/127 (25%), Positives = 55/127 (43%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FG+A G + D +GT + APE + SK+D++S G+ +E+ G Sbjct: 175 FGVA--GQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELARGEPPHS 232 Query: 252 KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 + P L+ P P LEGN+S + + ACL+++P RP Sbjct: 233 ELHPMKVLFLIPKNNP-------------PTLEGNYS----KPLKEFVEACLNKEPSFRP 275 Query: 432 LMSQVVE 452 ++++ Sbjct: 276 TAKELLK 282
>M3K11_HUMAN (Q16584) Mitogen-activated protein kinase kinase kinase 11 (EC| 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase) Length = 847 Score = 40.4 bits (93), Expect(2) = 3e-04 Identities = 22/57 (38%), Positives = 35/57 (61%), Gaps = 2/57 (3%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVM--GTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSG 236 FGLA++ H +T++ GTY + APE + + SDV+SFGV+L E+++G Sbjct: 268 FGLAREW------HKTTQMSAAGTYAWMAPEVIKASTFSKGSDVWSFGVLLWELLTG 318 Score = 22.3 bits (46), Expect(2) = 3e-04 Identities = 9/13 (69%), Positives = 12/13 (92%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 VI+RD K++NILL Sbjct: 237 VIHRDLKSNNILL 249
>FYN_XENLA (P13406) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 536 Score = 37.4 bits (85), Expect(2) = 3e-04 Identities = 28/96 (29%), Positives = 47/96 (48%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLLGERQRF 323 + APE + G T KSDV+SFG++L E+++ R N R +L + +R Sbjct: 431 WTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNN---------REVLEQVERG 481 Query: 324 YKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 Y++ P+ + S+ +L C +DP+ RP Sbjct: 482 YRMPCPQ-DCPISLH------ELMLNCWKKDPEERP 510 Score = 25.4 bits (54), Expect(2) = 3e-04 Identities = 11/30 (36%), Positives = 21/30 (70%) Frame = +1 Query: 4 IYRDFKTSNILLXFGIQCKALXILGLPKMV 93 I+RD +++NIL+ G+ CK + GL +++ Sbjct: 386 IHRDLRSANILVGNGLICK-IADFGLARLI 414
>SRC_RSVPA (P31693) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 522 Score = 40.4 bits (93), Expect(2) = 3e-04 Identities = 30/107 (28%), Positives = 46/107 (42%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLLGERQRF 323 + APE + G T KSDV+SFG++L E+ + R NGE +L +R Sbjct: 424 WTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNGE---------VLDRVERG 474 Query: 324 YKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARPLMSQVVEALKP 464 Y++ P + + L C +DP+ RP + L P Sbjct: 475 YRMPCP-------PECPESLHDLMCQCWRKDPEERPTFEYLQAQLLP 514 Score = 22.3 bits (46), Expect(2) = 3e-04 Identities = 9/30 (30%), Positives = 19/30 (63%) Frame = +1 Query: 4 IYRDFKTSNILLXFGIQCKALXILGLPKMV 93 ++RD + +NIL+ + CK + GL +++ Sbjct: 379 VHRDLRAANILVGENLVCK-VADFGLARLI 407
>PKN2_COREF (Q8FUI4) Serine/threonine protein kinases drp72 (EC 2.7.11.1)| Length = 520 Score = 43.5 bits (101), Expect = 3e-04 Identities = 26/57 (45%), Positives = 31/57 (54%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRR 242 FG+AK T V+GT Y +PE +T SDVYS GVV EM+SGRR Sbjct: 167 FGIAKAAASVPLTRTGM-VVGTAQYVSPEQAQGHQVTPASDVYSLGVVGYEMLSGRR 222
>ITK_MOUSE (Q03526) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK) Length = 625 Score = 43.5 bits (101), Expect = 3e-04 Identities = 31/109 (28%), Positives = 51/109 (46%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLLGERQRF 323 +A+PE +SKSDV+SFGV++ E+ S + +NR N E ++ + Sbjct: 529 WASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSE---------VVEDISTG 579 Query: 324 YKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARPLMSQVVEALKPLA 470 ++L PRL + Q+ C P+ RP SQ++ L +A Sbjct: 580 FRLYKPRL-------ASCHVYQIMNHCWKEKPEDRPPFSQLLSQLAEIA 621
>PKNA2_BIFLO (Q8G4G1) Probable serine/threonine-protein kinase pknA2 (EC| 2.7.11.1) Length = 757 Score = 43.5 bits (101), Expect = 3e-04 Identities = 24/65 (36%), Positives = 36/65 (55%), Gaps = 1/65 (1%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVST-RVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSM 248 FGLAK T ST ++GT Y APE + T++ D+YS G++ EM++G+ Sbjct: 159 FGLAK--AASQATLSSTGMLLGTAAYLAPEMIENNQATAQGDLYSVGIMAWEMLTGKVPF 216 Query: 249 DKNRP 263 D + P Sbjct: 217 DSDNP 221
>M3K10_HUMAN (Q02779) Mitogen-activated protein kinase kinase kinase 10 (EC| 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST) Length = 954 Score = 41.6 bits (96), Expect(2) = 4e-04 Identities = 23/67 (34%), Positives = 39/67 (58%), Gaps = 2/67 (2%) Frame = +3 Query: 42 IRNTMQSSQXFGLAKDGPVGDKTHVSTRVM--GTYGYAAPEYVMTGHLTSKSDVYSFGVV 215 + +T+ FGLA++ H +T++ GTY + APE + + SDV+SFGV+ Sbjct: 239 LADTVLKITDFGLAREW------HKTTKMSAAGTYAWMAPEVIRLSLFSKSSDVWSFGVL 292 Query: 216 LLEMMSG 236 L E+++G Sbjct: 293 LWELLTG 299 Score = 20.8 bits (42), Expect(2) = 4e-04 Identities = 8/18 (44%), Positives = 13/18 (72%) Frame = +1 Query: 1 VIYRDFKTSNILLXFGIQ 54 +I+RD K+ NIL+ I+ Sbjct: 218 IIHRDLKSINILILEAIE 235
>GRK4_HUMAN (P32298) G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK4) (ITI1) Length = 578 Score = 40.0 bits (92), Expect(2) = 4e-04 Identities = 35/121 (28%), Positives = 53/121 (43%), Gaps = 3/121 (2%) Frame = +3 Query: 75 GLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDK 254 GLA + P G + V RV GT GY APE V T D + G ++ EM+ G K Sbjct: 332 GLATEIPEGQR--VRGRV-GTVGYMAPEVVNNEKYTFSPDWWGLGCLIYEMIQGHSPFKK 388 Query: 255 NRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGN---FSVKGAQKAAQLARACLSRDPKA 425 + V+W VD R++ + +S K ++ A + R L+++P Sbjct: 389 YKEK-----VKWEE------------VDQRIKNDTEEYSEKFSEDAKSICRMLLTKNPSK 431 Query: 426 R 428 R Sbjct: 432 R 432 Score = 22.3 bits (46), Expect(2) = 4e-04 Identities = 8/13 (61%), Positives = 10/13 (76%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 ++YRD K NILL Sbjct: 308 IVYRDLKPENILL 320
>FYN_HUMAN (P06241) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) (Protooncogene Syn) (SLK) Length = 536 Score = 37.0 bits (84), Expect(2) = 4e-04 Identities = 28/96 (29%), Positives = 47/96 (48%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLLGERQRF 323 + APE + G T KSDV+SFG++L E+++ R N R +L + +R Sbjct: 431 WTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNN---------REVLEQVERG 481 Query: 324 YKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 Y++ P+ + S+ +L C +DP+ RP Sbjct: 482 YRMPCPQ-DCPISLH------ELMIHCWKKDPEERP 510 Score = 25.4 bits (54), Expect(2) = 4e-04 Identities = 11/30 (36%), Positives = 21/30 (70%) Frame = +1 Query: 4 IYRDFKTSNILLXFGIQCKALXILGLPKMV 93 I+RD +++NIL+ G+ CK + GL +++ Sbjct: 386 IHRDLRSANILVGNGLICK-IADFGLARLI 414
>FYN_MOUSE (P39688) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 37.0 bits (84), Expect(2) = 4e-04 Identities = 28/96 (29%), Positives = 47/96 (48%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLLGERQRF 323 + APE + G T KSDV+SFG++L E+++ R N R +L + +R Sbjct: 428 WTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNN---------REVLEQVERG 478 Query: 324 YKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 Y++ P+ + S+ +L C +DP+ RP Sbjct: 479 YRMPCPQ-DCPISLH------ELMIHCWKKDPEERP 507 Score = 25.4 bits (54), Expect(2) = 4e-04 Identities = 11/30 (36%), Positives = 21/30 (70%) Frame = +1 Query: 4 IYRDFKTSNILLXFGIQCKALXILGLPKMV 93 I+RD +++NIL+ G+ CK + GL +++ Sbjct: 383 IHRDLRSANILVGNGLICK-IADFGLARLI 411
>FYN_CHICK (Q05876) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 37.0 bits (84), Expect(2) = 4e-04 Identities = 28/96 (29%), Positives = 47/96 (48%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLLGERQRF 323 + APE + G T KSDV+SFG++L E+++ R N R +L + +R Sbjct: 428 WTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNN---------REVLEQVERG 478 Query: 324 YKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 Y++ P+ + S+ +L C +DP+ RP Sbjct: 479 YRMPCPQ-DCPISLH------ELMIHCWKKDPEERP 507 Score = 25.4 bits (54), Expect(2) = 4e-04 Identities = 11/30 (36%), Positives = 21/30 (70%) Frame = +1 Query: 4 IYRDFKTSNILLXFGIQCKALXILGLPKMV 93 I+RD +++NIL+ G+ CK + GL +++ Sbjct: 383 IHRDLRSANILVGNGLICK-IADFGLARLI 411
>LCK_HUMAN (P06239) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell-specific protein-tyrosine kinase) Length = 508 Score = 38.9 bits (89), Expect(2) = 4e-04 Identities = 29/106 (27%), Positives = 47/106 (44%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLLGERQRF 323 + APE + G T KSDV+SFG++L E+++ R N E ++ +R Sbjct: 405 WTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPE---------VIQNLERG 455 Query: 324 YKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARPLMSQVVEALK 461 Y++V P ++ QL R C P+ RP + L+ Sbjct: 456 YRMVRPD-------NCPEELYQLMRLCWKERPEDRPTFDYLRSVLE 494 Score = 23.5 bits (49), Expect(2) = 4e-04 Identities = 10/30 (33%), Positives = 19/30 (63%) Frame = +1 Query: 4 IYRDFKTSNILLXFGIQCKALXILGLPKMV 93 I+RD + +NIL+ + CK + GL +++ Sbjct: 360 IHRDLRAANILVSDTLSCK-IADFGLARLI 388
>DDR1_RAT (Q63474) Epithelial discoidin domain-containing receptor 1 precursor| (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein- Length = 910 Score = 43.1 bits (100), Expect = 4e-04 Identities = 36/125 (28%), Positives = 58/125 (46%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FG++++ GD V R + + A E ++ G T+ SDV++FGV L E++ RS Sbjct: 782 FGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRSQP 841 Query: 252 KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 + E ++E A ++ R L P Q +L C SR+P+ RP Sbjct: 842 FGQLTDE-QVIENAGEFFRDQGRQVYLSRP-------PACPQTLYELMLRCWSREPEQRP 893 Query: 432 LMSQV 446 SQ+ Sbjct: 894 PFSQL 898
>ITK_HUMAN (Q08881) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT) Length = 620 Score = 43.1 bits (100), Expect = 4e-04 Identities = 30/109 (27%), Positives = 51/109 (46%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLLGERQRF 323 +A+PE +SKSDV+SFGV++ E+ S + +NR N E ++ + Sbjct: 524 WASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSE---------VVEDISTG 574 Query: 324 YKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARPLMSQVVEALKPLA 470 ++L PRL + Q+ C P+ RP S+++ L +A Sbjct: 575 FRLYKPRL-------ASTHVYQIMNHCWKERPEDRPAFSRLLRQLAEIA 616
>IKKB_DROME (Q9VEZ5) Inhibitor of nuclear factor kappa B kinase beta subunit| (EC 2.7.11.1) (DmIKK-beta) (Immune response deficient protein 5) (IKK-like protein) (Lipopolysaccharide-activated kinase) (DLAK) (Cactus kinase IKK) Length = 751 Score = 43.1 bits (100), Expect = 4e-04 Identities = 25/55 (45%), Positives = 35/55 (63%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSG 236 FGLA+ P D+T V + V+GT Y APE V G S D++SFGV+ E+++G Sbjct: 207 FGLARGTP--DQTMVQS-VVGTRHYYAPEVVENGFYNSTVDLWSFGVIAYELVTG 258
>LRRK1_MOUSE (Q3UHC2) Leucine-rich repeat serine/threonine-protein kinase 1 (EC| 2.7.11.1) Length = 2014 Score = 43.1 bits (100), Expect = 4e-04 Identities = 35/115 (30%), Positives = 53/115 (46%), Gaps = 3/115 (2%) Frame = +3 Query: 126 VMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRR-SMDKNRPNGEHNLVEWARPL 302 V GT GY APE K D++S+G+VL E++SG+R ++ ++ L + RP+ Sbjct: 1424 VEGTPGYQAPEIRPRIVYDEKVDMFSYGMVLYELLSGQRPALGHHQLQIVKKLSKGIRPV 1483 Query: 303 LG--ERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARPLMSQVVEALK 461 LG E +F++L L C P+ RPL VV +K Sbjct: 1484 LGQPEEVQFHRL-----------------QALMMECWDTKPEKRPLALSVVSQMK 1521
>M3K9_HUMAN (P80192) Mitogen-activated protein kinase kinase kinase 9 (EC| 2.7.11.25) (Mixed lineage kinase 1) Length = 1104 Score = 39.7 bits (91), Expect(2) = 5e-04 Identities = 22/67 (32%), Positives = 38/67 (56%), Gaps = 2/67 (2%) Frame = +3 Query: 42 IRNTMQSSQXFGLAKDGPVGDKTHVSTRVM--GTYGYAAPEYVMTGHLTSKSDVYSFGVV 215 + N + FGLA++ H +T++ GTY + APE + + SDV+S+GV+ Sbjct: 285 LSNKILKITDFGLAREW------HRTTKMSAAGTYAWMAPEVIRASMFSKGSDVWSYGVL 338 Query: 216 LLEMMSG 236 L E+++G Sbjct: 339 LWELLTG 345 Score = 22.3 bits (46), Expect(2) = 5e-04 Identities = 8/13 (61%), Positives = 12/13 (92%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 +I+RD K+SNIL+ Sbjct: 264 IIHRDLKSSNILI 276
>KS6A2_MOUSE (Q9WUT3) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (Protein-tyrosine kinase Mpk-9) (MAP kinase-activated protein kinase 1c) (M Length = 733 Score = 39.3 bits (90), Expect(2) = 5e-04 Identities = 23/55 (41%), Positives = 31/55 (56%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSG 236 FGL+K+ DK S GT Y APE V T +D +SFGV++ EM++G Sbjct: 203 FGLSKEATDHDKRAYS--FCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTG 255 Score = 22.7 bits (47), Expect(2) = 5e-04 Identities = 9/13 (69%), Positives = 10/13 (76%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 +IYRD K NILL Sbjct: 180 IIYRDLKPENILL 192
>KPC1_DROME (P05130) Protein kinase C, brain isozyme (EC 2.7.11.13) (PKC)| (dPKC53E(BR)) Length = 679 Score = 40.4 bits (93), Expect(2) = 5e-04 Identities = 22/60 (36%), Positives = 33/60 (55%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FG+ K+ VGDKT + GT Y APE ++ D +++GV+L EM+ G+ D Sbjct: 493 FGMCKENIVGDKT--TKTFCGTPDYIAPEIILYQPYGKSVDWWAYGVLLYEMLVGQPPFD 550 Score = 21.6 bits (44), Expect(2) = 5e-04 Identities = 7/13 (53%), Positives = 10/13 (76%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 ++YRD K N+LL Sbjct: 470 ILYRDLKLDNVLL 482
>KPCZ_RAT (P09217) Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)| Length = 592 Score = 39.7 bits (91), Expect(2) = 5e-04 Identities = 34/119 (28%), Positives = 56/119 (47%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 +G+ K+G +G ST GT Y APE + D ++ GV++ EMM+GR D Sbjct: 395 YGMCKEG-LGPGDTTST-FCGTPNYIAPEILRGEEYGFSVDWWALGVLMFEMMAGRSPFD 452 Query: 252 KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKAR 428 N + N ++ ++ E+ R+ SV KA+ + + L++DPK R Sbjct: 453 IITDNPDMNTEDYLFQVILEK-------PIRIPRFLSV----KASHVLKGFLNKDPKER 500 Score = 22.3 bits (46), Expect(2) = 5e-04 Identities = 8/13 (61%), Positives = 10/13 (76%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 +IYRD K N+LL Sbjct: 372 IIYRDLKLDNVLL 384
>KPCZ_MOUSE (Q02956) Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)| Length = 592 Score = 39.7 bits (91), Expect(2) = 5e-04 Identities = 34/119 (28%), Positives = 56/119 (47%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 +G+ K+G +G ST GT Y APE + D ++ GV++ EMM+GR D Sbjct: 395 YGMCKEG-LGPGDTTST-FCGTPNYIAPEILRGEEYGFSVDWWALGVLMFEMMAGRSPFD 452 Query: 252 KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKAR 428 N + N ++ ++ E+ R+ SV KA+ + + L++DPK R Sbjct: 453 IITDNPDMNTEDYLFQVILEK-------PIRIPRFLSV----KASHVLKGFLNKDPKER 500 Score = 22.3 bits (46), Expect(2) = 5e-04 Identities = 8/13 (61%), Positives = 10/13 (76%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 +IYRD K N+LL Sbjct: 372 IIYRDLKLDNVLL 384
>KPCZ_HUMAN (Q05513) Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)| Length = 592 Score = 39.7 bits (91), Expect(2) = 5e-04 Identities = 34/119 (28%), Positives = 56/119 (47%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 +G+ K+G +G ST GT Y APE + D ++ GV++ EMM+GR D Sbjct: 395 YGMCKEG-LGPGDTTST-FCGTPNYIAPEILRGEEYGFSVDWWALGVLMFEMMAGRSPFD 452 Query: 252 KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKAR 428 N + N ++ ++ E+ R+ SV KA+ + + L++DPK R Sbjct: 453 IITDNPDMNTEDYLFQVILEK-------PIRIPRFLSV----KASHVLKGFLNKDPKER 500 Score = 22.3 bits (46), Expect(2) = 5e-04 Identities = 8/13 (61%), Positives = 10/13 (76%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 +IYRD K N+LL Sbjct: 372 IIYRDLKLDNVLL 384
>KPCZ_RABIT (O19111) Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)| Length = 591 Score = 39.7 bits (91), Expect(2) = 5e-04 Identities = 34/119 (28%), Positives = 56/119 (47%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 +G+ K+G +G ST GT Y APE + D ++ GV++ EMM+GR D Sbjct: 394 YGMCKEG-LGPGDTTST-FCGTPNYIAPEILRGEEYGFSVDWWALGVLMFEMMAGRSPFD 451 Query: 252 KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKAR 428 N + N ++ ++ E+ R+ SV KA+ + + L++DPK R Sbjct: 452 IITDNPDMNTEDYLFQVILEK-------PIRIPRFLSV----KASHVLKGFLNKDPKER 499 Score = 22.3 bits (46), Expect(2) = 5e-04 Identities = 8/13 (61%), Positives = 10/13 (76%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 +IYRD K N+LL Sbjct: 371 IIYRDLKLDNVLL 383
>YES_XIPHE (P27447) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 543 Score = 38.5 bits (88), Expect(2) = 6e-04 Identities = 27/106 (25%), Positives = 47/106 (44%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLLGERQRF 323 + APE + G T KSDV+SFG++L E+++ R N R +L + R Sbjct: 438 WTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMVN---------REVLEQVDRG 488 Query: 324 YKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARPLMSQVVEALK 461 Y++ P+ + ++ R C ++P RP + L+ Sbjct: 489 YRMPCPQ-------GCPESLHEMMRQCWKKEPDERPTFEYIQSFLE 527 Score = 23.5 bits (49), Expect(2) = 6e-04 Identities = 10/30 (33%), Positives = 19/30 (63%) Frame = +1 Query: 4 IYRDFKTSNILLXFGIQCKALXILGLPKMV 93 I+RD + +NIL+ + CK + GL +++ Sbjct: 393 IHRDLRAANILVADNLVCK-IADFGLARLI 421
>LRRK1_HUMAN (Q38SD2) Leucine-rich repeat serine/threonine-protein kinase 1 (EC| 2.7.11.1) Length = 2038 Score = 42.7 bits (99), Expect = 6e-04 Identities = 34/113 (30%), Positives = 53/113 (46%), Gaps = 1/113 (0%) Frame = +3 Query: 126 VMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRR-SMDKNRPNGEHNLVEWARPL 302 V GT GY APE K D++S+G+VL E++SG+R ++ ++ L + RP+ Sbjct: 1447 VEGTPGYQAPEIRPRIVYDEKVDMFSYGMVLYELLSGQRPALGHHQLQIAKKLSKGIRPV 1506 Query: 303 LGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARPLMSQVVEALK 461 LG+ + E F ++ L C P+ RPL VV +K Sbjct: 1507 LGQPE----------EVQF-----RRLQALMMECWDTKPEKRPLALSVVSQMK 1544
>PTK6_HUMAN (Q13882) Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor| kinase) (Tyrosine-protein kinase BRK) Length = 451 Score = 42.7 bits (99), Expect = 6e-04 Identities = 37/137 (27%), Positives = 59/137 (43%) Frame = +3 Query: 48 NTMQSSQXFGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEM 227 NT+ FGLA+ + + ++S Y + APE + GH ++KSDV+SFG++L EM Sbjct: 323 NTLCKVGDFGLAR--LIKEDVYLSHDHNIPYKWTAPEALSRGHYSTKSDVWSFGILLHEM 380 Query: 228 MSGRRSMDKNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACL 407 S + P + + F + VD ++ +L C Sbjct: 381 FSRG---------------QVPYPGMSNHEAFLR-VDAGYRMPCPLECPPSVHKLMLTCW 424 Query: 408 SRDPKARPLMSQVVEAL 458 RDP+ RP + E L Sbjct: 425 CRDPEQRPCFKALRERL 441
>PKNA_MYCLE (P54743) Probable serine/threonine-protein kinase pknA (EC| 2.7.11.1) Length = 437 Score = 42.7 bits (99), Expect = 6e-04 Identities = 25/57 (43%), Positives = 31/57 (54%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRR 242 FG+AK T VMGT Y APE + T SDVYS GV+ E++SG+R Sbjct: 160 FGIAKAVDAAPVTQTGM-VMGTAQYIAPEQALGHDATPASDVYSLGVIGYEVVSGKR 215
>FYN_XIPHE (P27446) Proto-oncogene tyrosine-protein kinase FYN (EC 2.7.10.2)| (P59-FYN) Length = 536 Score = 38.1 bits (87), Expect(2) = 7e-04 Identities = 27/96 (28%), Positives = 44/96 (45%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLLGERQRF 323 + APE + G T KSDV+SFG++L E+++ R N R +L + +R Sbjct: 431 WTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNN---------REVLEQVERG 481 Query: 324 YKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 Y++ P+ +L C +DP+ RP Sbjct: 482 YRMPCPQ-------DCPASLHELMLQCWKKDPEERP 510 Score = 23.5 bits (49), Expect(2) = 7e-04 Identities = 10/30 (33%), Positives = 20/30 (66%) Frame = +1 Query: 4 IYRDFKTSNILLXFGIQCKALXILGLPKMV 93 I+RD +++NIL+ + CK + GL +++ Sbjct: 386 IHRDLRSANILVGDNLVCK-IADFGLARLI 414
>TMKL1_ARATH (P33543) Putative kinase-like protein TMKL1 precursor| Length = 674 Score = 42.4 bits (98), Expect = 7e-04 Identities = 32/110 (29%), Positives = 51/110 (46%), Gaps = 3/110 (2%) Frame = +3 Query: 141 GYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEH-NLVEWARPLLGERQ 317 GY APE +SDVY+FG++LLE++ G++ R E +L + + E Sbjct: 541 GYKAPELHKMKKCNPRSDVYAFGILLLEILMGKKPGKSGRNGNEFVDLPSLVKAAVLEET 600 Query: 318 RFYKLVDPRLEGNFS--VKGAQKAAQLARACLSRDPKARPLMSQVVEALK 461 ++G S +G A +LA C + RP M +VV+ L+ Sbjct: 601 TMEVFDLEAMKGIRSPMEEGLVHALKLAMGCCAPVTTVRPSMEEVVKQLE 650
>MKH1_SCHPO (Q10407) MAP kinase kinase kinase mkh1 (EC 2.7.11.25)| Length = 1116 Score = 37.0 bits (84), Expect(2) = 9e-04 Identities = 20/59 (33%), Positives = 33/59 (55%), Gaps = 2/59 (3%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGH--LTSKSDVYSFGVVLLEMMSGRR 242 FG++K + + G+ + APE + H ++K DV+S G V+LEM++GRR Sbjct: 974 FGISKHSDNVYDNDANLSMQGSIFWMAPEVIHNDHQGYSAKVDVWSLGCVVLEMLAGRR 1032 Score = 24.3 bits (51), Expect(2) = 9e-04 Identities = 9/20 (45%), Positives = 13/20 (65%) Frame = +1 Query: 1 VIYRDFKTSNILLXFGIQCK 60 +I+RD K N+L+ F CK Sbjct: 951 IIHRDLKADNLLIDFDGVCK 970
>M3KL4_HUMAN (Q5TCX8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase 4) Length = 1036 Score = 38.9 bits (89), Expect(2) = 9e-04 Identities = 20/57 (35%), Positives = 36/57 (63%), Gaps = 2/57 (3%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVM--GTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSG 236 FGLA++ H +T++ GTY + APE + + + SD++S+GV+L E+++G Sbjct: 290 FGLAREW------HRTTKMSTAGTYAWMAPEVIKSSLFSKGSDIWSYGVLLWELLTG 340 Score = 22.3 bits (46), Expect(2) = 9e-04 Identities = 8/13 (61%), Positives = 12/13 (92%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 +++RD K+SNILL Sbjct: 259 ILHRDLKSSNILL 271
>KS6A2_HUMAN (Q15349) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (MAP kinase-activated protein kinase 1c) (MAPKAPK1C) Length = 733 Score = 38.5 bits (88), Expect(2) = 0.001 Identities = 23/55 (41%), Positives = 31/55 (56%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSG 236 FGL+K+ DK S GT Y APE V T +D +SFGV++ EM++G Sbjct: 203 FGLSKEAIDHDKRAYS--FCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTG 255 Score = 22.7 bits (47), Expect(2) = 0.001 Identities = 9/13 (69%), Positives = 10/13 (76%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 +IYRD K NILL Sbjct: 180 IIYRDLKPENILL 192
>GRK6_MOUSE (O70293) G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK6) Length = 576 Score = 38.9 bits (89), Expect(2) = 0.001 Identities = 36/118 (30%), Positives = 49/118 (41%) Frame = +3 Query: 75 GLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDK 254 GLA P G + RV GT GY APE V T D ++ G +L EM++G+ + Sbjct: 331 GLAVHVPEGQT--IKGRV-GTVGYMAPEVVRNERYTFSPDWWALGCLLYEMIAGQSPFQQ 387 Query: 255 NRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKAR 428 + + VE R K V FS + +QL LS+DP R Sbjct: 388 RKKKIKREEVE----------RLVKEVAEEYTDRFSSQARSLCSQL----LSKDPAER 431 Score = 22.3 bits (46), Expect(2) = 0.001 Identities = 8/13 (61%), Positives = 10/13 (76%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 ++YRD K NILL Sbjct: 307 IVYRDLKPENILL 319
>SRC_RSVH1 (P25020) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 38.9 bits (89), Expect(2) = 0.001 Identities = 29/107 (27%), Positives = 46/107 (42%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLLGERQRF 323 + APE + G T KSDV+SFG++L E+ + R N R +L + +R Sbjct: 427 WTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVN---------REVLDQVERA 477 Query: 324 YKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARPLMSQVVEALKP 464 Y++ P + + L C +DP+ RP + L P Sbjct: 478 YRMPCP-------PECPESLHDLMCQCWRKDPEERPTFKYLQAQLLP 517 Score = 22.3 bits (46), Expect(2) = 0.001 Identities = 9/30 (30%), Positives = 19/30 (63%) Frame = +1 Query: 4 IYRDFKTSNILLXFGIQCKALXILGLPKMV 93 ++RD + +NIL+ + CK + GL +++ Sbjct: 382 VHRDLRAANILVGENLVCK-VADFGLARLI 410
>DDR1_MOUSE (Q03146) Epithelial discoidin domain-containing receptor 1 precursor| (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protei Length = 911 Score = 42.0 bits (97), Expect = 0.001 Identities = 35/125 (28%), Positives = 58/125 (46%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FG++++ GD V R + + A E ++ G T+ SDV++FGV L E++ RS Sbjct: 783 FGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRSQP 842 Query: 252 KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 + E ++E A ++ R L P Q +L C SR+P+ RP Sbjct: 843 FGQLTDE-QVIENAGEFFRDQGRQVYLSRP-------PACPQTLYELMLRCWSREPEQRP 894 Query: 432 LMSQV 446 +Q+ Sbjct: 895 PFAQL 899
>KPC2_DROME (P13677) Protein kinase C, eye isozyme (EC 2.7.11.13) (PKC)| (dPKC53E(EY)) (Protein INAC) (Inactivation no after-potential C protein) (Photoreceptor-specific PKC) (Eye-PKC) Length = 700 Score = 38.1 bits (87), Expect(2) = 0.001 Identities = 24/57 (42%), Positives = 33/57 (57%), Gaps = 1/57 (1%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVM-GTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGR 239 FGL+K+G +T TR GT Y APE V + +D +SFGV+L E M+G+ Sbjct: 514 FGLSKEGVTERQT---TRTFCGTPNYMAPEIVSYDPYSIAADWWSFGVLLFEFMAGQ 567 Score = 22.7 bits (47), Expect(2) = 0.001 Identities = 9/13 (69%), Positives = 10/13 (76%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 +IYRD K NILL Sbjct: 491 IIYRDLKLDNILL 503
>SRC_RSVP (P00526) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 38.5 bits (88), Expect(2) = 0.001 Identities = 29/107 (27%), Positives = 46/107 (42%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLLGERQRF 323 + APE + G T KSDV+SFG++L E+ + R N R +L + +R Sbjct: 427 WTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVN---------REVLDQVERG 477 Query: 324 YKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARPLMSQVVEALKP 464 Y++ P + + L C +DP+ RP + L P Sbjct: 478 YRMPCP-------PECPESLHDLMCQCWRKDPEERPTFKYLQAQLLP 517 Score = 22.3 bits (46), Expect(2) = 0.001 Identities = 9/30 (30%), Positives = 19/30 (63%) Frame = +1 Query: 4 IYRDFKTSNILLXFGIQCKALXILGLPKMV 93 ++RD + +NIL+ + CK + GL +++ Sbjct: 382 VHRDLRAANILVGENLVCK-VADFGLARLI 410
>PDK1L_BRARE (Q32PP3) Serine/threonine-protein kinase pdik1l (EC 2.7.11.1)| Length = 341 Score = 39.7 bits (91), Expect(2) = 0.001 Identities = 37/131 (28%), Positives = 57/131 (43%), Gaps = 12/131 (9%) Frame = +3 Query: 75 GLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDK 254 GL + P + GT Y APE V GH T+K+D+++ GV++ M+ +D Sbjct: 201 GLNPEEPASVNKCFLSTACGTDFYMAPE-VWEGHYTAKADIFALGVIIWAMVERITFVD- 258 Query: 255 NRPNGEHNLVEWARPLLGERQRFYK---------LVDPRLEGNFSVKGAQKAA---QLAR 398 VE + LLG + + L +P++E N + A QL R Sbjct: 259 ---------VETQKELLGSYVQQGEDIVPLGEALLENPKMELNIPARKKSMNASMKQLIR 309 Query: 399 ACLSRDPKARP 431 LS +P+ RP Sbjct: 310 EMLSANPQERP 320 Score = 21.2 bits (43), Expect(2) = 0.001 Identities = 8/16 (50%), Positives = 11/16 (68%) Frame = +1 Query: 1 VIYRDFKTSNILLXFG 48 +I+RD K NIL+ G Sbjct: 160 IIHRDLKPDNILISQG 175
>NEK9_MOUSE (Q8K1R7) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)| (NimA-related protein kinase 9) (Never in mitosis A-related kinase 9) Length = 984 Score = 41.6 bits (96), Expect = 0.001 Identities = 30/128 (23%), Positives = 60/128 (46%), Gaps = 1/128 (0%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 +GLAK + + ++ ++GT Y +PE KSD+++ G V+ E+++ +R+ D Sbjct: 195 YGLAKK--LNSEYSMAETLVGTPYYMSPELCQGVKYNFKSDIWAVGCVIFELLTLKRTFD 252 Query: 252 KNRP-NGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKAR 428 P N +V+ R + + ++ + + QL ACL +DP+ R Sbjct: 253 ATNPLNLCVKIVQGIRAMEVDSSQY----------------SLELIQLVHACLDQDPEQR 296 Query: 429 PLMSQVVE 452 P +++ Sbjct: 297 PAADALLD 304
>PKN6_MYXXA (P54738) Serine/threonine-protein kinase pkn6 (EC 2.7.11.1)| Length = 710 Score = 41.6 bits (96), Expect = 0.001 Identities = 22/60 (36%), Positives = 32/60 (53%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FG+AK G +T V G Y PE + + + DVY+ GVVL E+++G+R D Sbjct: 162 FGIAKVAGQGHRTLTGV-VKGKVAYMPPEQLQAKAMDRRVDVYALGVVLYELLTGKRPFD 220
>PKN2_CLOAB (Q97IC2) Probable serine/threonine protein kinase CAC1728 (EC| 2.7.11.1) Length = 657 Score = 41.6 bits (96), Expect = 0.001 Identities = 22/64 (34%), Positives = 36/64 (56%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FG+AK T + +V+G+ Y +PE + ++D+YSFG+VL EM +G+ D Sbjct: 152 FGIAKASNESTIT-TTNKVVGSAHYLSPEQAQGIPVDCRTDIYSFGIVLYEMATGKVPYD 210 Query: 252 KNRP 263 + P Sbjct: 211 ADTP 214
>M3K7_HUMAN (O43318) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 606 Score = 41.6 bits (96), Expect = 0.001 Identities = 33/121 (27%), Positives = 56/121 (46%) Frame = +3 Query: 105 KTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLV 284 +TH+ T G+ + APE + + K DV+S+G++L E+++ R+ D+ G + Sbjct: 183 QTHM-TNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDE--IGGPAFRI 239 Query: 285 EWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARPLMSQVVEALKP 464 WA G R K + +E L C S+DP RP M ++V+ + Sbjct: 240 MWA-VHNGTRPPLIKNLPKPIE------------SLMTRCWSKDPSQRPSMEEIVKIMTH 286 Query: 465 L 467 L Sbjct: 287 L 287
>M3K7_MOUSE (Q62073) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 579 Score = 41.6 bits (96), Expect = 0.001 Identities = 33/121 (27%), Positives = 56/121 (46%) Frame = +3 Query: 105 KTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLV 284 +TH+ T G+ + APE + + K DV+S+G++L E+++ R+ D+ G + Sbjct: 183 QTHM-TNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDE--IGGPAFRI 239 Query: 285 EWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARPLMSQVVEALKP 464 WA G R K + +E L C S+DP RP M ++V+ + Sbjct: 240 MWA-VHNGTRPPLIKNLPKPIE------------SLMTRCWSKDPSQRPSMEEIVKIMTH 286 Query: 465 L 467 L Sbjct: 287 L 287
>ULK2_MOUSE (Q9QY01) Serine/threonine-protein kinase ULK2 (EC 2.7.11.1)| (Unc-51-like kinase 2) (Serine/threonine-protein kinase Unc51.2) Length = 1037 Score = 38.1 bits (87), Expect(2) = 0.001 Identities = 18/64 (28%), Positives = 33/64 (51%) Frame = +3 Query: 114 VSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWA 293 ++ + G+ Y APE +M+ H +K+D++S G V+ + + G+ N P E Sbjct: 170 MAATLCGSPMYMAPEVIMSQHYDAKADLWSIGTVIYQCLVGKPPFQANSPQDLRMFYEKN 229 Query: 294 RPLL 305 R L+ Sbjct: 230 RSLM 233 Score = 22.3 bits (46), Expect(2) = 0.001 Identities = 9/21 (42%), Positives = 14/21 (66%) Frame = +1 Query: 1 VIYRDFKTSNILLXFGIQCKA 63 +I+RD K NILL + + K+ Sbjct: 127 IIHRDLKPQNILLSYANRRKS 147
>ULK2_HUMAN (Q8IYT8) Serine/threonine-protein kinase ULK2 (EC 2.7.11.1)| (Unc-51-like kinase 2) Length = 1036 Score = 38.1 bits (87), Expect(2) = 0.001 Identities = 18/64 (28%), Positives = 33/64 (51%) Frame = +3 Query: 114 VSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWA 293 ++ + G+ Y APE +M+ H +K+D++S G V+ + + G+ N P E Sbjct: 170 MAATLCGSPMYMAPEVIMSQHYDAKADLWSIGTVIYQCLVGKPPFQANSPQDLRMFYEKN 229 Query: 294 RPLL 305 R L+ Sbjct: 230 RSLM 233 Score = 22.3 bits (46), Expect(2) = 0.001 Identities = 9/21 (42%), Positives = 14/21 (66%) Frame = +1 Query: 1 VIYRDFKTSNILLXFGIQCKA 63 +I+RD K NILL + + K+ Sbjct: 127 IIHRDLKPQNILLSYANRRKS 147
>KPC3_CAEEL (Q19266) Protein kinase C-like 3 (EC 2.7.11.13) (Atypical protein| kinase C-3) (aPKC3) Length = 597 Score = 38.9 bits (89), Expect(2) = 0.002 Identities = 34/120 (28%), Positives = 56/120 (46%), Gaps = 1/120 (0%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 +G+ K+ + D ST GT Y APE + D ++ GV++ EMM+GR D Sbjct: 396 YGMCKEN-IKDGDLTST-FCGTPNYIAPEILRGDEYGFSVDWWALGVLMFEMMAGRSPFD 453 Query: 252 -KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKAR 428 N E N ++ ++ ERQ R+ + SV +A+ + + L++DP R Sbjct: 454 IVGMQNSEENTEDYLFQIILERQ-------IRIPRSLSV----RASGILKGFLNKDPTER 502 Score = 21.6 bits (44), Expect(2) = 0.002 Identities = 7/13 (53%), Positives = 10/13 (76%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 +IYRD K N+L+ Sbjct: 373 IIYRDLKLDNVLI 385
>YES_HUMAN (P07947) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 542 Score = 37.4 bits (85), Expect(2) = 0.002 Identities = 27/106 (25%), Positives = 46/106 (43%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLLGERQRF 323 + APE + G T KSDV+SFG++ E+++ R N R +L + +R Sbjct: 437 WTAPEAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVN---------REVLEQVERG 487 Query: 324 YKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARPLMSQVVEALK 461 Y++ P+ + +L C +DP RP + L+ Sbjct: 488 YRMPCPQ-------GCPESLHELMNLCWKKDPDERPTFEYIQSFLE 526 Score = 23.1 bits (48), Expect(2) = 0.002 Identities = 10/30 (33%), Positives = 19/30 (63%) Frame = +1 Query: 4 IYRDFKTSNILLXFGIQCKALXILGLPKMV 93 I+RD + +NIL+ + CK + GL +++ Sbjct: 392 IHRDLRAANILVGENLVCK-IADFGLARLI 420
>YES_MOUSE (Q04736) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 540 Score = 37.4 bits (85), Expect(2) = 0.002 Identities = 27/106 (25%), Positives = 46/106 (43%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLLGERQRF 323 + APE + G T KSDV+SFG++ E+++ R N R +L + +R Sbjct: 435 WTAPEAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVN---------REVLEQVERG 485 Query: 324 YKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARPLMSQVVEALK 461 Y++ P+ + +L C +DP RP + L+ Sbjct: 486 YRMPCPQ-------GCPESLHELMNLCWKKDPDERPTFEYIQSFLE 524 Score = 22.7 bits (47), Expect(2) = 0.002 Identities = 10/30 (33%), Positives = 19/30 (63%) Frame = +1 Query: 4 IYRDFKTSNILLXFGIQCKALXILGLPKMV 93 I+RD + +NIL+ + CK + GL +++ Sbjct: 390 IHRDLRAANILVGENLICK-IADFGLARLI 418
>NEK9_HUMAN (Q8TD19) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)| (NimA-related protein kinase 9) (Never in mitosis A-related kinase 9) (Nercc1 kinase) (NIMA-related kinase 8) (Nek8) Length = 979 Score = 40.8 bits (94), Expect = 0.002 Identities = 28/128 (21%), Positives = 61/128 (47%), Gaps = 1/128 (0%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 +GLAK + + ++ ++GT Y +PE KSD+++ G V+ E+++ +R+ D Sbjct: 195 YGLAKK--LNSEYSMAETLVGTPYYMSPELCQGVKYNFKSDIWAVGCVIFELLTLKRTFD 252 Query: 252 KNRP-NGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKAR 428 P N +V+ R + + ++ + + Q+ +CL +DP+ R Sbjct: 253 ATNPLNLCVKIVQGIRAMEVDSSQY----------------SLELIQMVHSCLDQDPEQR 296 Query: 429 PLMSQVVE 452 P ++++ Sbjct: 297 PTADELLD 304
>PKSC_STRCO (Q9S2C0) Serine/threonine protein kinase pksC (EC 2.7.11.1)| Length = 556 Score = 40.8 bits (94), Expect = 0.002 Identities = 21/65 (32%), Positives = 38/65 (58%), Gaps = 1/65 (1%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVST-RVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSM 248 FG+A+ G + T V+GT Y +PE + + ++SD+YS G++L ++++GR Sbjct: 170 FGIARAMQSGVTSMTQTGMVVGTPQYLSPEQALGRGVDARSDLYSVGIMLFQLVTGRLPF 229 Query: 249 DKNRP 263 D + P Sbjct: 230 DADSP 234
>M3K7_DROME (Q9V3Q6) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (TGF-beta-activated kinase 1) (dTAK1) Length = 678 Score = 40.8 bits (94), Expect = 0.002 Identities = 34/120 (28%), Positives = 51/120 (42%) Frame = +3 Query: 90 GPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNG 269 G V DK+ + T G+ + APE T K D++S+ +VL E++S R+ K N Sbjct: 161 GTVADKSTMMTNNRGSAAWMAPEVFEGSKYTEKCDIFSWAIVLWEVLS-RKQPFKGIDNA 219 Query: 270 EHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARPLMSQVV 449 ++W + GER R+E L AC P+ RP M +V Sbjct: 220 --YTIQW-KIYKGERPPLLTTCPKRIE------------DLMTACWKTVPEDRPSMQYIV 264
>PKNA_MYCTU (P65726) Probable serine/threonine-protein kinase pknA (EC| 2.7.11.1) Length = 431 Score = 40.8 bits (94), Expect = 0.002 Identities = 25/57 (43%), Positives = 30/57 (52%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRR 242 FG+AK T VMGT Y APE + + SDVYS GVV E +SG+R Sbjct: 160 FGIAKAVDAAPVTQTGM-VMGTAQYIAPEQALGHDASPASDVYSLGVVGYEAVSGKR 215
>PKNA_MYCBO (P65727) Probable serine/threonine-protein kinase pknA (EC| 2.7.11.1) Length = 431 Score = 40.8 bits (94), Expect = 0.002 Identities = 25/57 (43%), Positives = 30/57 (52%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRR 242 FG+AK T VMGT Y APE + + SDVYS GVV E +SG+R Sbjct: 160 FGIAKAVDAAPVTQTGM-VMGTAQYIAPEQALGHDASPASDVYSLGVVGYEAVSGKR 215
>CCAMK_PEA (Q6RET6) Calcium and calcium/calmodulin-dependent| serine/threonine-protein kinase (EC 2.7.11.17) (PsCCaMK) (Ps-SYM9) (Fragment) Length = 527 Score = 40.8 bits (94), Expect = 0.002 Identities = 37/132 (28%), Positives = 59/132 (44%), Gaps = 6/132 (4%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FGL+ V + T + G+ Y +PE + G +T+KSD++S GV+L ++SG Sbjct: 201 FGLSS---VEEFTDPVVGLFGSIDYVSPEALSQGKITTKSDMWSLGVILYILLSG----- 252 Query: 252 KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSV-----KG-AQKAAQLARACLSR 413 P + + R + L GNFS KG +Q A L + L+ Sbjct: 253 -------------YPPFIAQNNR--QKQQMILNGNFSFYEKTWKGISQSAKNLISSLLTV 297 Query: 414 DPKARPLMSQVV 449 DP RP +++ Sbjct: 298 DPAKRPSAQELL 309
>PKN3_MYXXA (Q9XBQ0) Serine/threonine-protein kinase pkn3 (EC 2.7.11.1)| Length = 547 Score = 40.8 bits (94), Expect = 0.002 Identities = 35/131 (26%), Positives = 55/131 (41%), Gaps = 3/131 (2%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTR---VMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRR 242 FG+AK D TR V GT Y +PE L +SD+Y+ GV+L ++M+G Sbjct: 165 FGIAKITDSTDDGPALTRAGFVCGTPEYMSPEQARGSQLDHRSDLYAVGVILYQLMTGLL 224 Query: 243 SMDKNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPK 422 + + G P R+R + P +E +L LS++P Sbjct: 225 PFESDSAVGFATKHLTEEPPPPTRRRPDARISPAME------------RLILRALSKNPA 272 Query: 423 ARPLMSQVVEA 455 RP ++ +A Sbjct: 273 DRPASAEAFKA 283
>KS6A3_MOUSE (P18654) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B) Length = 740 Score = 37.0 bits (84), Expect(2) = 0.003 Identities = 22/55 (40%), Positives = 31/55 (56%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSG 236 FGL+K+ +K S GT Y APE V T +D +SFGV++ EM++G Sbjct: 212 FGLSKESIDHEKKAYS--FCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTG 264 Score = 22.7 bits (47), Expect(2) = 0.003 Identities = 9/13 (69%), Positives = 10/13 (76%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 +IYRD K NILL Sbjct: 189 IIYRDLKPENILL 201
>KS6A3_HUMAN (P51812) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protei Length = 740 Score = 37.0 bits (84), Expect(2) = 0.003 Identities = 22/55 (40%), Positives = 31/55 (56%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSG 236 FGL+K+ +K S GT Y APE V T +D +SFGV++ EM++G Sbjct: 212 FGLSKESIDHEKKAYS--FCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTG 264 Score = 22.7 bits (47), Expect(2) = 0.003 Identities = 9/13 (69%), Positives = 10/13 (76%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 +IYRD K NILL Sbjct: 189 IIYRDLKPENILL 201
>KPCI_BRARE (Q90XF2) Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota)| (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (Heart and soul protein) Length = 588 Score = 37.4 bits (85), Expect(2) = 0.003 Identities = 34/122 (27%), Positives = 58/122 (47%), Gaps = 3/122 (2%) Frame = +3 Query: 72 FGLAKDG-PVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSM 248 +G+ K+G GD T + GT Y APE + D ++ GV++ EMM+GR Sbjct: 389 YGMCKEGLRPGDTT---STFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPF 445 Query: 249 D--KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPK 422 D + N + N ++ ++ E+Q R+ + SV KAA + + L+++ K Sbjct: 446 DIVGSSDNPDQNTEDYLFQVILEKQ-------IRIPRSLSV----KAASVLKGFLNKESK 494 Query: 423 AR 428 R Sbjct: 495 ER 496 Score = 22.3 bits (46), Expect(2) = 0.003 Identities = 8/13 (61%), Positives = 10/13 (76%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 +IYRD K N+LL Sbjct: 366 IIYRDLKLDNVLL 378
>GRK6_HUMAN (P43250) G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK6) Length = 576 Score = 37.4 bits (85), Expect(2) = 0.003 Identities = 35/118 (29%), Positives = 48/118 (40%) Frame = +3 Query: 75 GLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDK 254 GLA P G + RV GT GY APE V T D ++ G +L EM++G+ + Sbjct: 331 GLAVHVPEGQT--IKGRV-GTVGYMAPEVVKNERYTFSPDWWALGCLLYEMIAGQSPFQQ 387 Query: 255 NRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKAR 428 + + VE R K V FS + +QL L +DP R Sbjct: 388 RKKKIKREEVE----------RLVKEVPEEYSERFSPQARSLCSQL----LCKDPAER 431 Score = 22.3 bits (46), Expect(2) = 0.003 Identities = 8/13 (61%), Positives = 10/13 (76%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 ++YRD K NILL Sbjct: 307 IVYRDLKPENILL 319
>YES_CANFA (Q28923) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 538 Score = 36.6 bits (83), Expect(2) = 0.003 Identities = 27/106 (25%), Positives = 45/106 (42%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLLGERQRF 323 + APE + G T KSDV+SFG++ E+ + R N R +L + +R Sbjct: 433 WTAPEAALYGRFTIKSDVWSFGILQTELTTKGRVPYPGMVN---------REVLEQVERG 483 Query: 324 YKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARPLMSQVVEALK 461 Y++ P+ + +L C +DP RP + L+ Sbjct: 484 YRMPCPQ-------GCPESLHELMNLCWKKDPDERPTFEYIQSFLE 522 Score = 23.1 bits (48), Expect(2) = 0.003 Identities = 10/30 (33%), Positives = 19/30 (63%) Frame = +1 Query: 4 IYRDFKTSNILLXFGIQCKALXILGLPKMV 93 I+RD + +NIL+ + CK + GL +++ Sbjct: 388 IHRDLRAANILVGENLVCK-IADFGLARLI 416
>PDK1B_XENLA (Q6NU98) Serine/threonine-protein kinase pdik1l-B (EC 2.7.11.1)| Length = 339 Score = 40.4 bits (93), Expect = 0.003 Identities = 39/130 (30%), Positives = 57/130 (43%), Gaps = 11/130 (8%) Frame = +3 Query: 75 GLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDK 254 GL + P + GT Y APE V GH T+K+D+++ GV+L M+ D Sbjct: 199 GLNPEEPANVNKSFLSTACGTDFYMAPE-VWEGHYTAKADIFALGVILWAMLERITITDT 257 Query: 255 NRPNGEHNLVEWARPLLGERQRFYKLV--------DPRLEGNFSVKGA---QKAAQLARA 401 + R L G QR ++V +P+LE VK ++ QL R Sbjct: 258 HTKK---------RLLGGYVQRGAQVVPVGEALLENPKLELLIPVKKKSMNRRMKQLLRQ 308 Query: 402 CLSRDPKARP 431 LS +P+ RP Sbjct: 309 MLSANPQERP 318
>KPC1_APLCA (Q16974) Calcium-dependent protein kinase C (EC 2.7.11.13) (APL I)| Length = 649 Score = 40.4 bits (93), Expect = 0.003 Identities = 24/61 (39%), Positives = 35/61 (57%), Gaps = 1/61 (1%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVM-GTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSM 248 FG+ K+ +GDKT TR GT Y APE V+ D +++GV+L EM++G+ Sbjct: 463 FGMCKENIMGDKT---TRTFCGTPDYIAPEIVLYQPYGRSVDWWAYGVLLYEMLAGQPPF 519 Query: 249 D 251 D Sbjct: 520 D 520
>SRC_AVIS2 (P15054) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 586 Score = 37.0 bits (84), Expect(2) = 0.003 Identities = 27/96 (28%), Positives = 43/96 (44%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLLGERQRF 323 + APE + G T KSDV+SFG++L E+ + R N R +L + +R Sbjct: 427 WTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVN---------REVLDQVERG 477 Query: 324 YKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 Y++ P + + L C +DP+ RP Sbjct: 478 YRMPCP-------PECPESLHDLMCQCWRKDPEERP 506 Score = 22.3 bits (46), Expect(2) = 0.003 Identities = 9/30 (30%), Positives = 19/30 (63%) Frame = +1 Query: 4 IYRDFKTSNILLXFGIQCKALXILGLPKMV 93 ++RD + +NIL+ + CK + GL +++ Sbjct: 382 VHRDLRAANILVGENLVCK-VADFGLARLI 410
>SRC_AVISS (P14084) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 567 Score = 37.0 bits (84), Expect(2) = 0.003 Identities = 27/96 (28%), Positives = 43/96 (44%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLLGERQRF 323 + APE + G T KSDV+SFG++L E+ + R N R +L + +R Sbjct: 427 WTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVN---------REVLDQVERG 477 Query: 324 YKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 Y++ P + + L C +DP+ RP Sbjct: 478 YRMPCP-------PECPESLHDLMCQCWRKDPEERP 506 Score = 22.3 bits (46), Expect(2) = 0.003 Identities = 9/30 (30%), Positives = 19/30 (63%) Frame = +1 Query: 4 IYRDFKTSNILLXFGIQCKALXILGLPKMV 93 ++RD + +NIL+ + CK + GL +++ Sbjct: 382 VHRDLRAANILVGENLVCK-VADFGLARLI 410
>SRC_AVIST (P14085) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 556 Score = 37.0 bits (84), Expect(2) = 0.003 Identities = 27/96 (28%), Positives = 43/96 (44%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLLGERQRF 323 + APE + G T KSDV+SFG++L E+ + R N R +L + +R Sbjct: 427 WTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVN---------REVLDQVERG 477 Query: 324 YKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 Y++ P + + L C +DP+ RP Sbjct: 478 YRMPCP-------PECPESLHDLMCQCWRKDPEERP 506 Score = 22.3 bits (46), Expect(2) = 0.003 Identities = 9/30 (30%), Positives = 19/30 (63%) Frame = +1 Query: 4 IYRDFKTSNILLXFGIQCKALXILGLPKMV 93 ++RD + +NIL+ + CK + GL +++ Sbjct: 382 VHRDLRAANILVGENLVCK-VADFGLARLI 410
>SRC_CHICK (P00523) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 532 Score = 37.0 bits (84), Expect(2) = 0.003 Identities = 27/96 (28%), Positives = 43/96 (44%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLLGERQRF 323 + APE + G T KSDV+SFG++L E+ + R N R +L + +R Sbjct: 427 WTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVN---------REVLDQVERG 477 Query: 324 YKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 Y++ P + + L C +DP+ RP Sbjct: 478 YRMPCP-------PECPESLHDLMCQCWRKDPEERP 506 Score = 22.3 bits (46), Expect(2) = 0.003 Identities = 9/30 (30%), Positives = 19/30 (63%) Frame = +1 Query: 4 IYRDFKTSNILLXFGIQCKALXILGLPKMV 93 ++RD + +NIL+ + CK + GL +++ Sbjct: 382 VHRDLRAANILVGENLVCK-VADFGLARLI 410
>LCK_CHICK (P42683) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (Protein-tyrosine kinase C-TKL) (p56tk1) Length = 507 Score = 36.2 bits (82), Expect(2) = 0.003 Identities = 27/106 (25%), Positives = 45/106 (42%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLLGERQRF 323 + APE + G T KSDV+SFG++L E+++ R N E ++ +R Sbjct: 404 WTAPEAINYGTFTIKSDVWSFGILLTEIVTYGRIPYPGMTNPE---------VIQNLERG 454 Query: 324 YKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARPLMSQVVEALK 461 Y++ P Q+ +L C P+ RP + L+ Sbjct: 455 YRMPQPD-------NCPQELYELMMQCWKEQPEERPTFEYMKSVLE 493 Score = 23.1 bits (48), Expect(2) = 0.003 Identities = 10/30 (33%), Positives = 19/30 (63%) Frame = +1 Query: 4 IYRDFKTSNILLXFGIQCKALXILGLPKMV 93 I+RD + +NIL+ + CK + GL +++ Sbjct: 359 IHRDLRAANILVSEALCCK-IADFGLARLI 387
>RIPK3_RAT (Q9Z2P5) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (Homocysteine respondent protein HCYP2) Length = 478 Score = 37.4 bits (85), Expect(2) = 0.003 Identities = 33/103 (32%), Positives = 47/103 (45%), Gaps = 3/103 (2%) Frame = +3 Query: 132 GTYGYAAPEYVMTGHLTSK-SDVYSFGVVLLEMMSGRRS--MDKNRPNGEHNLVEWARPL 302 GT Y APE + SK SDVYSFGV++ +++GR + +DK R Sbjct: 184 GTLAYLAPELLDNDGKASKASDVYSFGVLVWTVLAGREAEVVDK---------TSLIRGA 234 Query: 303 LGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 + RQR L + + G + +L C S +PK RP Sbjct: 235 VCNRQRRPPLTELPPDSP-ETPGLEGLKELMTHCWSSEPKDRP 276 Score = 21.9 bits (45), Expect(2) = 0.003 Identities = 8/20 (40%), Positives = 13/20 (65%) Frame = +1 Query: 1 VIYRDFKTSNILLXFGIQCK 60 +++RD K SN+LL + K Sbjct: 139 LLHRDLKPSNVLLDLELHAK 158
>KRAC_DICDI (P54644) RAC-family serine/threonine-protein kinase homolog (EC| 2.7.11.1) Length = 444 Score = 37.0 bits (84), Expect(2) = 0.003 Identities = 33/119 (27%), Positives = 48/119 (40%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FGL K+G + T GT Y APE + + D +SFG +L EM++G Sbjct: 262 FGLCKEGLLTPTDKTGT-FCGTPEYLAPEVLQGNGYGKQVDWWSFGSLLYEMLTGL---- 316 Query: 252 KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKAR 428 P ++ E R ++ E+ F + P A L L RDP+ R Sbjct: 317 --PPFYNQDVQEMYRKIMMEKLSFPHFISP------------DARSLLEQLLERDPEKR 361 Score = 22.3 bits (46), Expect(2) = 0.003 Identities = 9/13 (69%), Positives = 10/13 (76%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 VIYRD K N+LL Sbjct: 239 VIYRDLKPENLLL 251
>NEK7_MOUSE (Q9ES74) Serine/threonine-protein kinase Nek7 (EC 2.7.11.1)| (NimA-related protein kinase 7) Length = 302 Score = 40.0 bits (92), Expect = 0.004 Identities = 33/139 (23%), Positives = 58/139 (41%), Gaps = 10/139 (7%) Frame = +3 Query: 75 GLAKDGPVG------DKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSG 236 G+ K G +G KT + ++GT Y +PE + KSD++S G +L EM + Sbjct: 173 GVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAA- 231 Query: 237 RRSMDKNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNF----SVKGAQKAAQLARAC 404 P G++ Y L + ++ S +++ QL C Sbjct: 232 -----------------LQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNIC 274 Query: 405 LSRDPKARPLMSQVVEALK 461 ++ DP+ RP ++ V + K Sbjct: 275 INPDPEKRPDIAYVYDVAK 293
>NEK7_HUMAN (Q8TDX7) Serine/threonine-protein kinase Nek7 (EC 2.7.11.1)| (NimA-related protein kinase 7) Length = 302 Score = 40.0 bits (92), Expect = 0.004 Identities = 33/139 (23%), Positives = 58/139 (41%), Gaps = 10/139 (7%) Frame = +3 Query: 75 GLAKDGPVG------DKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSG 236 G+ K G +G KT + ++GT Y +PE + KSD++S G +L EM + Sbjct: 173 GVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAA- 231 Query: 237 RRSMDKNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNF----SVKGAQKAAQLARAC 404 P G++ Y L + ++ S +++ QL C Sbjct: 232 -----------------LQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNMC 274 Query: 405 LSRDPKARPLMSQVVEALK 461 ++ DP+ RP ++ V + K Sbjct: 275 INPDPEKRPDVTYVYDVAK 293
>RIPK3_HUMAN (Q9Y572) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) Length = 518 Score = 40.0 bits (92), Expect = 0.004 Identities = 30/104 (28%), Positives = 47/104 (45%), Gaps = 4/104 (3%) Frame = +3 Query: 132 GTYGYAAPEYVMTGH--LTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLV--EWARP 299 GT GY APE + + ++ SDVYSFG+++ +++GR P+ + V RP Sbjct: 181 GTLGYLAPELFVNVNRKASTASDVYSFGILMWAVLAGREVELPTEPSLVYEAVCNRQNRP 240 Query: 300 LLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 L E + G + +L + C S +PK RP Sbjct: 241 SLAELP----------QAGPETPGLEGLKELMQLCWSSEPKDRP 274
>PKNL_MYCTU (O53510) Probable serine/threonine-protein kinase pknL (EC| 2.7.11.1) Length = 399 Score = 40.0 bits (92), Expect = 0.004 Identities = 20/55 (36%), Positives = 31/55 (56%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSG 236 FGL + T ++GT Y +PE V G+ +SDVYS GV++ E+++G Sbjct: 161 FGLVRAVAAASITSTGV-ILGTAAYLSPEQVRDGNADPRSDVYSVGVLVYELLTG 214
>PKNL_MYCBO (Q7TYY6) Probable serine/threonine-protein kinase pknL (EC| 2.7.11.1) Length = 399 Score = 40.0 bits (92), Expect = 0.004 Identities = 20/55 (36%), Positives = 31/55 (56%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSG 236 FGL + T ++GT Y +PE V G+ +SDVYS GV++ E+++G Sbjct: 161 FGLVRAVAAASITSTGV-ILGTAAYLSPEQVRDGNADPRSDVYSVGVLVYELLTG 214
>SPK1_DUGTI (P42687) Tyrosine-protein kinase SPK-1 (EC 2.7.10.2)| Length = 497 Score = 40.0 bits (92), Expect = 0.004 Identities = 22/56 (39%), Positives = 35/56 (62%), Gaps = 2/56 (3%) Frame = +3 Query: 72 FGLAK--DGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMS 233 FGL + DG +GD+ + R Y + APE + TSKSDV+S+G+V+ E+++ Sbjct: 361 FGLTELTDGSLGDQEKKTLRF--PYKWTAPEAAKSKVFTSKSDVWSYGIVMFEILT 414
>MST4_HUMAN (Q9P289) Serine/threonine-protein kinase MST4 (EC 2.7.11.1)| (STE20-like kinase MST4) (MST-4) (Mammalian STE20-like protein kinase 4) (Serine/threonine-protein kinase MASK) (Mst3 and SOK1-related kinase) Length = 416 Score = 40.0 bits (92), Expect = 0.004 Identities = 31/127 (24%), Positives = 53/127 (41%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FG+A G + D +GT + APE + SK+D++S G+ +E+ G Sbjct: 163 FGVA--GQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPNS 220 Query: 252 KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 P L+ P P L G+F+ + + ACL++DP RP Sbjct: 221 DMHPMRVLFLIPKNNP-------------PTLVGDFT----KSFKEFIDACLNKDPSFRP 263 Query: 432 LMSQVVE 452 ++++ Sbjct: 264 TAKELLK 270
>PKN2_MYXXA (P54736) Serine/threonine-protein kinase pkn2 (EC 2.7.11.1)| Length = 830 Score = 40.0 bits (92), Expect = 0.004 Identities = 33/100 (33%), Positives = 48/100 (48%), Gaps = 8/100 (8%) Frame = +3 Query: 126 VMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPN---GEHNL----- 281 V+GT Y +PE + + ++SD+YSFGV+ ++SGR D P +H Sbjct: 177 VLGTPEYLSPEQAVGAKVDTRSDLYSFGVLTYRVLSGRLPFDGPLPRNFLSQHASAAPLP 236 Query: 282 VEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARA 401 ++ A P L LV LE + S K Q A +LA A Sbjct: 237 LDRAAPTLSRYVGLLSLVMRLLEKDAS-KRPQSAHELADA 275
>LRRK2_HUMAN (Q5S007) Leucine-rich repeat serine/threonine-protein kinase 2 (EC| 2.7.11.1) (Dardarin) Length = 2527 Score = 37.0 bits (84), Expect(2) = 0.004 Identities = 34/112 (30%), Positives = 58/112 (51%), Gaps = 3/112 (2%) Frame = +3 Query: 132 GTYGYAAPEYVMTGHL--TSKSDVYSFGVVLLEMM-SGRRSMDKNRPNGEHNLVEWARPL 302 GT G+ APE V G++ ++DVYSFG++L +++ +G R ++ + E + +E + Sbjct: 2034 GTPGFRAPE-VARGNVIYNQQADVYSFGLLLYDILTTGGRIVEGLKFPNEFDELE----I 2088 Query: 303 LGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARPLMSQVVEAL 458 G KL DP E + +L + CL +P+ RP +QV + L Sbjct: 2089 QG------KLPDPVKE--YGCAPWPMVEKLIKQCLKENPQERPTSAQVFDIL 2132 Score = 21.9 bits (45), Expect(2) = 0.004 Identities = 8/13 (61%), Positives = 10/13 (76%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 +IYRD K N+LL Sbjct: 1990 IIYRDLKPHNVLL 2002
>SSK2_YEAST (P53599) MAP kinase kinase kinase SSK2 (EC 2.7.11.25) (Suppressor of| sensor kinase 2) Length = 1579 Score = 37.0 bits (84), Expect(2) = 0.004 Identities = 28/68 (41%), Positives = 34/68 (50%), Gaps = 16/68 (23%) Frame = +3 Query: 87 DGPVGDKTHVSTR------------VMGTYGYAAPEYVMTGHLTS----KSDVYSFGVVL 218 DG D THVS +MGT Y APE + TG T DV+S G V+ Sbjct: 1432 DGEHEDVTHVSDSKAVKNNENALLDMMGTPMYMAPESI-TGSTTKGKLGADDVWSLGCVV 1490 Query: 219 LEMMSGRR 242 LEM++GRR Sbjct: 1491 LEMITGRR 1498 Score = 21.9 bits (45), Expect(2) = 0.004 Identities = 8/15 (53%), Positives = 11/15 (73%) Frame = +1 Query: 1 VIYRDFKTSNILLXF 45 +++RD K NILL F Sbjct: 1386 IVHRDVKPENILLDF 1400
>KPCE_MOUSE (P16054) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 737 Score = 33.9 bits (76), Expect(2) = 0.004 Identities = 19/56 (33%), Positives = 30/56 (53%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGR 239 FG+ K+G + T +T GT Y APE + D ++ GV++ EMM+G+ Sbjct: 551 FGMCKEGIMNGVT--TTTFCGTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQ 604 Score = 25.0 bits (53), Expect(2) = 0.004 Identities = 12/20 (60%), Positives = 12/20 (60%) Frame = +1 Query: 1 VIYRDFKTSNILLXFGIQCK 60 VIYRD K NILL CK Sbjct: 528 VIYRDLKLDNILLDAEGHCK 547
>KPCE_HUMAN (Q02156) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 737 Score = 33.9 bits (76), Expect(2) = 0.004 Identities = 19/56 (33%), Positives = 30/56 (53%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGR 239 FG+ K+G + T +T GT Y APE + D ++ GV++ EMM+G+ Sbjct: 551 FGMCKEGILNGVT--TTTFCGTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQ 604 Score = 25.0 bits (53), Expect(2) = 0.004 Identities = 12/20 (60%), Positives = 12/20 (60%) Frame = +1 Query: 1 VIYRDFKTSNILLXFGIQCK 60 VIYRD K NILL CK Sbjct: 528 VIYRDLKLDNILLDAEGHCK 547
>KPCE_RABIT (P10830) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 736 Score = 33.9 bits (76), Expect(2) = 0.004 Identities = 19/56 (33%), Positives = 30/56 (53%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGR 239 FG+ K+G + T +T GT Y APE + D ++ GV++ EMM+G+ Sbjct: 550 FGMCKEGILNGVT--TTTFCGTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQ 603 Score = 25.0 bits (53), Expect(2) = 0.004 Identities = 12/20 (60%), Positives = 12/20 (60%) Frame = +1 Query: 1 VIYRDFKTSNILLXFGIQCK 60 VIYRD K NILL CK Sbjct: 527 VIYRDLKLDNILLDAEGHCK 546
>KPCT_HUMAN (Q04759) Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)| Length = 706 Score = 36.6 bits (83), Expect(2) = 0.004 Identities = 20/56 (35%), Positives = 30/56 (53%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGR 239 FG+ K+ +GD + GT Y APE ++ D +SFGV+L EM+ G+ Sbjct: 523 FGMCKENMLGDAK--TNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQ 576 Score = 22.3 bits (46), Expect(2) = 0.004 Identities = 8/13 (61%), Positives = 10/13 (76%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 ++YRD K NILL Sbjct: 500 IVYRDLKLDNILL 512
>PKAA_STRCO (P54739) Serine/threonine protein kinase pkaA (EC 2.7.11.1)| Length = 543 Score = 38.1 bits (87), Expect(2) = 0.004 Identities = 37/135 (27%), Positives = 55/135 (40%), Gaps = 2/135 (1%) Frame = +3 Query: 72 FGLAK--DGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRS 245 FG+A+ D P +TH +GT Y APE TS DVY G++L E+++GR Sbjct: 164 FGIARLADSPGLTRTH---EFVGTPAYVAPESAEGRPQTSAVDVYGAGILLYELVTGRPP 220 Query: 246 MDKNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKA 425 G L + L E +R + DP + CL ++P Sbjct: 221 F-----GGGSALEVLHQHLSAEPRRPSTVPDP-------------LWTVIERCLRKNPDD 262 Query: 426 RPLMSQVVEALKPLA 470 RP + L+ +A Sbjct: 263 RPSAENLARGLRVVA 277 Score = 20.8 bits (42), Expect(2) = 0.004 Identities = 7/13 (53%), Positives = 11/13 (84%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 V++RD K +N+LL Sbjct: 138 VVHRDLKPANVLL 150
>KYK1_DICDI (P18160) Non-receptor tyrosine kinase spore lysis A (EC 2.7.10.2)| (Tyrosine-protein kinase 1) Length = 1584 Score = 39.7 bits (91), Expect = 0.005 Identities = 28/116 (24%), Positives = 49/116 (42%) Frame = +3 Query: 120 TRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARP 299 T+ +G Y APE + KSDVYS+G+VL E+++ +P +L Sbjct: 1463 TQSVGCIPYMAPEVFKGDSNSEKSDVYSYGMVLFELLTSDEPQQDMKPMKMAHLAA---- 1518 Query: 300 LLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARPLMSQVVEALKPL 467 Y+ P + + + K ++ C +P +RP Q++ LK + Sbjct: 1519 --------YESYRPPI----PLTTSSKWKEILTQCWDSNPDSRPTFKQIIVHLKEM 1562
>MST4_MOUSE (Q99JT2) Serine/threonine-protein kinase MST4 (EC 2.7.11.1)| (STE20-like kinase MST4) (MST-4) (Mammalian STE20-like protein kinase 4) Length = 416 Score = 39.7 bits (91), Expect = 0.005 Identities = 31/127 (24%), Positives = 53/127 (41%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FG+A G + D +GT + APE + SK+D++S G+ +E+ G Sbjct: 163 FGVA--GQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPNS 220 Query: 252 KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 P L+ P P L G+F+ + + ACL++DP RP Sbjct: 221 DMHPMRVLFLIPKNNP-------------PTLIGDFT----KSFKEFIDACLNKDPSFRP 263 Query: 432 LMSQVVE 452 ++++ Sbjct: 264 TAKELLK 270
>JIL1_DROME (Q9V3I5) Chromosomal serine/threonine-protein kinase JIL-1 (EC| 2.7.11.1) Length = 1207 Score = 39.7 bits (91), Expect = 0.005 Identities = 31/116 (26%), Positives = 50/116 (43%), Gaps = 9/116 (7%) Frame = +3 Query: 135 TYGYAAPEYVMTGHLTSKS---DVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLL 305 T YA PE + +L + S D+Y G L M+ G R +N + +H+ A L Sbjct: 779 TLDYAPPEMLADANLVTYSPAVDIYGLGATLYTMLVGHRPYRQNEDDVDHSAA--AHHEL 836 Query: 306 GERQRFYKLVDPRLEGNFSVKGAQKAA------QLARACLSRDPKARPLMSQVVEA 455 +R R G F+ + + + L CL RDP RP +S ++++ Sbjct: 837 RKRMR---------RGTFNQRSMRWESASPAFRHLVSWCLQRDPADRPTLSDILDS 883
>STK25_MOUSE (Q9Z2W1) Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Sterile| 20/oxidant stress-response kinase 1) (Ste20/oxidant stress response kinase 1) (SOK-1) (Ste20-like kinase) Length = 426 Score = 39.7 bits (91), Expect = 0.005 Identities = 31/127 (24%), Positives = 53/127 (41%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FG+A G + D +GT + APE + K+D++S G+ +E+ G Sbjct: 159 FGVA--GQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNS 216 Query: 252 KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 P L+ P P LEG+ S + + ACL++DP+ RP Sbjct: 217 DLHPMRVLFLIPKNNP-------------PTLEGHHS----KPFKEFVEACLNKDPRFRP 259 Query: 432 LMSQVVE 452 ++++ Sbjct: 260 TAKELLK 266
>CCAMK_MEDTR (Q6RET7) Calcium and calcium/calmodulin-dependent| serine/threonine-protein kinase DMI-3 (EC 2.7.11.17) (Does not make infections protein 3) (CCaMK DMI3) (MtCCaMK) Length = 523 Score = 39.7 bits (91), Expect = 0.005 Identities = 36/126 (28%), Positives = 56/126 (44%), Gaps = 6/126 (4%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FGL+ V + T + G+ Y +PE + G +T+KSD++S GV+L ++SG Sbjct: 193 FGLSS---VEEFTDPVVGLFGSIDYVSPEALSQGKITTKSDMWSLGVILYILLSG----- 244 Query: 252 KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSV-----KG-AQKAAQLARACLSR 413 P + + R + + GNFS KG +Q A L + L+ Sbjct: 245 -------------YPPFIAQNNR--QKQQMIMNGNFSFYEKTWKGISQPAKNLISSLLTV 289 Query: 414 DPKARP 431 DP RP Sbjct: 290 DPSKRP 295
>IRAK2_HUMAN (O43187) Interleukin-1 receptor-associated kinase-like 2 (IRAK-2)| Length = 590 Score = 39.7 bits (91), Expect = 0.005 Identities = 19/52 (36%), Positives = 32/52 (61%), Gaps = 1/52 (1%) Frame = +3 Query: 108 THVSTRVMGTYGYAAPE-YVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNR 260 T + T ++ T PE ++ G LT + D++S G+VL E+++G +MD NR Sbjct: 368 TMMKTHLLRTSAAYLPEDFIRVGQLTKRVDIFSCGIVLAEVLTGIPAMDNNR 419
>E2AK1_HUMAN (Q9BQI3) Eukaryotic translation initiation factor 2-alpha kinase 1| (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Heme-controlled repressor) (HCR) (Hemin-sensitive initiation factor Length = 630 Score = 39.7 bits (91), Expect = 0.005 Identities = 20/43 (46%), Positives = 27/43 (62%) Frame = +3 Query: 99 GDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEM 227 G +T T +GT YA+PE + +KSD+YS GVVLLE+ Sbjct: 481 GKRTPTHTSRVGTCLYASPEQLEGSEYDAKSDMYSLGVVLLEL 523
>MEK2_CAEEL (Q10664) Dual specificity mitogen-activated protein kinase kinase| mek-2 (EC 2.7.12.2) (MAP kinase kinase mek-2) Length = 387 Score = 39.7 bits (91), Expect = 0.005 Identities = 17/37 (45%), Positives = 25/37 (67%) Frame = +3 Query: 129 MGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGR 239 +GT Y APE + H T SD++SFG+ L+E++ GR Sbjct: 229 VGTRSYMAPERLTGSHYTISSDIWSFGLSLVELLIGR 265
>KPC3_DROME (P13678) Protein kinase C (EC 2.7.11.13) (PKC) (dPKC98F)| Length = 634 Score = 33.9 bits (76), Expect(2) = 0.005 Identities = 18/56 (32%), Positives = 31/56 (55%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGR 239 FG+ K+G + ++T GT Y APE + + D ++ GV++ EMM+G+ Sbjct: 446 FGMCKEGIMNGM--LTTTFCGTPDYIAPEILKEQEYGASVDWWALGVLMYEMMAGQ 499 Score = 24.6 bits (52), Expect(2) = 0.005 Identities = 12/20 (60%), Positives = 12/20 (60%) Frame = +1 Query: 1 VIYRDFKTSNILLXFGIQCK 60 VIYRD K NILL CK Sbjct: 423 VIYRDLKLDNILLDQEGHCK 442
>FGR_FSVGR (P00544) Tyrosine-protein kinase transforming protein Fgr (EC| 2.7.10.2) Length = 545 Score = 36.2 bits (82), Expect(2) = 0.005 Identities = 16/33 (48%), Positives = 23/33 (69%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRR 242 + APE + G T KSDV+SFG++L E++S R Sbjct: 447 WTAPEAALFGRFTIKSDVWSFGILLTELISKGR 479 Score = 22.3 bits (46), Expect(2) = 0.005 Identities = 10/30 (33%), Positives = 19/30 (63%) Frame = +1 Query: 4 IYRDFKTSNILLXFGIQCKALXILGLPKMV 93 I+RD + +NIL+ + CK + GL +++ Sbjct: 402 IHRDLRAANILVGERLVCK-IADFGLARLI 430
>SRC2_XENLA (P13116) Tyrosine-protein kinase Src-2 (EC 2.7.10.2) (p60-Src-2)| Length = 531 Score = 36.2 bits (82), Expect(2) = 0.005 Identities = 27/96 (28%), Positives = 42/96 (43%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLLGERQRF 323 + APE + G T KSDV+SFG++L E+ + R N R +L + +R Sbjct: 426 WTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVN---------REVLDQVERG 476 Query: 324 YKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 Y++ P + L C +DP+ RP Sbjct: 477 YRMPCP-------PDCPESLHDLMFQCWRKDPEERP 505 Score = 22.3 bits (46), Expect(2) = 0.005 Identities = 9/30 (30%), Positives = 19/30 (63%) Frame = +1 Query: 4 IYRDFKTSNILLXFGIQCKALXILGLPKMV 93 ++RD + +NIL+ + CK + GL +++ Sbjct: 381 VHRDLRAANILVGENLVCK-VADFGLARLI 409
>SRC1_XENLA (P13115) Tyrosine-protein kinase Src-1 (EC 2.7.10.2) (p60-Src-1)| Length = 531 Score = 36.2 bits (82), Expect(2) = 0.005 Identities = 27/96 (28%), Positives = 42/96 (43%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLLGERQRF 323 + APE + G T KSDV+SFG++L E+ + R N R +L + +R Sbjct: 426 WTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVN---------REVLDQVERG 476 Query: 324 YKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 Y++ P + L C +DP+ RP Sbjct: 477 YRMPCP-------PDCPESLHDLMFQCWRKDPEERP 505 Score = 22.3 bits (46), Expect(2) = 0.005 Identities = 9/30 (30%), Positives = 19/30 (63%) Frame = +1 Query: 4 IYRDFKTSNILLXFGIQCKALXILGLPKMV 93 ++RD + +NIL+ + CK + GL +++ Sbjct: 381 VHRDLRAANILVGENLVCK-VADFGLARLI 409
>E2AK1_MOUSE (Q9Z2R9) Eukaryotic translation initiation factor 2-alpha kinase 1| (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Heme-controlled repressor) (HCR) (Hemin-sensitive initiation factor Length = 619 Score = 39.3 bits (90), Expect = 0.006 Identities = 20/43 (46%), Positives = 28/43 (65%) Frame = +3 Query: 99 GDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEM 227 G +TH S +GT YA+PE + +KSD+YS GV+LLE+ Sbjct: 480 GTRTHTSR--VGTCLYASPEQLEGSQYDAKSDMYSLGVILLEL 520
>PKNB_MYCLE (P54744) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 622 Score = 39.3 bits (90), Expect = 0.006 Identities = 22/57 (38%), Positives = 34/57 (59%), Gaps = 2/57 (3%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVS--TRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSG 236 FG+A+ + D T V+ V+GT Y +PE + ++SDVYS G VL E+++G Sbjct: 157 FGIAR--AIADSTSVTQTAAVIGTAQYLSPEQARGDSVDARSDVYSLGCVLYEILTG 211
>EPHAA_HUMAN (Q5JZY3) Ephrin type-A receptor 10 precursor (EC 2.7.10.1)| Length = 1008 Score = 39.3 bits (90), Expect = 0.006 Identities = 30/108 (27%), Positives = 51/108 (47%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLLGERQRF 323 +AAPE + GH +S SDV+SFG+++ E+M+ RP + + + ++ + Sbjct: 812 WAAPETLQFGHFSSASDVWSFGIIMWEVMA-----FGERPYWDMS----GQDVIKAVEDG 862 Query: 324 YKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARPLMSQVVEALKPL 467 ++L PR N +L C +DP RP SQ+ L + Sbjct: 863 FRLPPPRNCPNL-------LHRLMLDCWQKDPGERPRFSQIHSILSKM 903
>KPC2_APLCA (Q16975) Calcium-independent protein kinase C (EC 2.7.11.13) (APL| II) Length = 743 Score = 33.5 bits (75), Expect(2) = 0.007 Identities = 18/56 (32%), Positives = 31/56 (55%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGR 239 FG+ K+G +K ++ GT Y APE + + D ++ GV++ EMM+G+ Sbjct: 546 FGMCKEGMTENK--LTQTFCGTPDYIAPEILQELKYDASVDWWALGVLMYEMMAGQ 599 Score = 24.6 bits (52), Expect(2) = 0.007 Identities = 11/20 (55%), Positives = 12/20 (60%) Frame = +1 Query: 1 VIYRDFKTSNILLXFGIQCK 60 +IYRD K NILL CK Sbjct: 523 IIYRDLKLDNILLDAEGHCK 542
>KS6A1_RAT (Q63531) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 35.4 bits (80), Expect(2) = 0.007 Identities = 21/55 (38%), Positives = 31/55 (56%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSG 236 FGL+K+ +K S GT Y APE V T +D +S+GV++ EM++G Sbjct: 206 FGLSKEAIDHEKKAYS--FCGTVEYMAPEVVNRQGHTHSADWWSYGVLMFEMLTG 258 Score = 22.7 bits (47), Expect(2) = 0.007 Identities = 9/13 (69%), Positives = 10/13 (76%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 +IYRD K NILL Sbjct: 183 IIYRDLKPENILL 195
>KPC1_CAEEL (P34722) Protein kinase C-like 1 (EC 2.7.11.13) (PKC)| (Tetradecanoyl phorbol acetate resistant protein 1) Length = 704 Score = 35.8 bits (81), Expect(2) = 0.007 Identities = 31/119 (26%), Positives = 52/119 (43%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FG+AK + + +++ GT Y +PE + D +SFGV++ EM+ G+ Sbjct: 518 FGMAKT-EMNRENGMASTFCGTPDYISPEIIKGQLYNEAVDFWSFGVLMYEMLVGQSPF- 575 Query: 252 KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKAR 428 GE L + +L ER F K + +++AA+ A R+P R Sbjct: 576 --HGEGEDELFD---SILNERPYFPKTI------------SKEAAKCLSALFDRNPNTR 617 Score = 22.3 bits (46), Expect(2) = 0.007 Identities = 8/13 (61%), Positives = 10/13 (76%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 +IYRD K N+LL Sbjct: 495 IIYRDLKLDNVLL 507
>HCK_HUMAN (P08631) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p59-HCK/p60-HCK) (Hemopoietic cell kinase) Length = 525 Score = 34.7 bits (78), Expect(2) = 0.007 Identities = 14/30 (46%), Positives = 23/30 (76%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMS 233 + APE + G T KSDV+SFG++L+E+++ Sbjct: 422 WTAPEAINFGSFTIKSDVWSFGILLMEIVT 451 Score = 23.5 bits (49), Expect(2) = 0.007 Identities = 10/30 (33%), Positives = 19/30 (63%) Frame = +1 Query: 4 IYRDFKTSNILLXFGIQCKALXILGLPKMV 93 I+RD + +NIL+ + CK + GL +++ Sbjct: 377 IHRDLRAANILVSASLVCK-IADFGLARVI 405
>HCK_MOUSE (P08103) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK) Length = 523 Score = 34.7 bits (78), Expect(2) = 0.007 Identities = 14/30 (46%), Positives = 23/30 (76%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMS 233 + APE + G T KSDV+SFG++L+E+++ Sbjct: 420 WTAPEAINFGSFTIKSDVWSFGILLMEIVT 449 Score = 23.5 bits (49), Expect(2) = 0.007 Identities = 10/30 (33%), Positives = 19/30 (63%) Frame = +1 Query: 4 IYRDFKTSNILLXFGIQCKALXILGLPKMV 93 I+RD + +NIL+ + CK + GL +++ Sbjct: 375 IHRDLRAANILVSASLVCK-IADFGLARII 403
>LCK_AOTNA (Q5PXS1) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 34.7 bits (78), Expect(2) = 0.007 Identities = 27/106 (25%), Positives = 45/106 (42%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLLGERQRF 323 + APE + G T KSDV+SFG++L E+++ R N E ++ +R Sbjct: 405 WTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPE---------VIQNLERG 455 Query: 324 YKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARPLMSQVVEALK 461 Y++V P ++ L C P+ RP + L+ Sbjct: 456 YRMVRPD-------NCPEELYHLMMLCWKERPEDRPTFDYLRSVLE 494 Score = 23.5 bits (49), Expect(2) = 0.007 Identities = 10/30 (33%), Positives = 19/30 (63%) Frame = +1 Query: 4 IYRDFKTSNILLXFGIQCKALXILGLPKMV 93 I+RD + +NIL+ + CK + GL +++ Sbjct: 360 IHRDLRAANILVSDTLSCK-IADFGLARLI 388
>HCK_RAT (P50545) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 502 Score = 34.7 bits (78), Expect(2) = 0.007 Identities = 14/30 (46%), Positives = 23/30 (76%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMS 233 + APE + G T KSDV+SFG++L+E+++ Sbjct: 399 WTAPEAINFGSFTIKSDVWSFGILLMEIVT 428 Score = 23.5 bits (49), Expect(2) = 0.007 Identities = 10/30 (33%), Positives = 19/30 (63%) Frame = +1 Query: 4 IYRDFKTSNILLXFGIQCKALXILGLPKMV 93 I+RD + +NIL+ + CK + GL +++ Sbjct: 354 IHRDLRAANILVSASLVCK-IADFGLARII 382
>SUR1_CAEEL (P39745) Mitogen-activated protein kinase mpk-1 (EC 2.7.11.24) (MAP| kinase sur-1) Length = 444 Score = 37.0 bits (84), Expect(2) = 0.007 Identities = 24/58 (41%), Positives = 32/58 (55%), Gaps = 2/58 (3%) Frame = +3 Query: 72 FGLAK-DGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKS-DVYSFGVVLLEMMSGR 239 FGLA+ P D T T + T Y APE ++ +KS DV+S G +L EM+S R Sbjct: 239 FGLARVTDPQTDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDVWSVGCILAEMLSNR 296 Score = 21.2 bits (43), Expect(2) = 0.007 Identities = 8/13 (61%), Positives = 11/13 (84%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 V++RD K SN+LL Sbjct: 216 VLHRDLKPSNLLL 228
>TOPK_HUMAN (Q96KB5) T-lymphokine-activated killer cell-originated protein| kinase (EC 2.7.12.2) (T-LAK cell-originated protein kinase) (PDZ-binding kinase) (Spermatogenesis-related protein kinase) (SPK) (MAPKK-like protein kinase) (Nori-3) Length = 322 Score = 38.9 bits (89), Expect = 0.008 Identities = 28/99 (28%), Positives = 48/99 (48%), Gaps = 2/99 (2%) Frame = +3 Query: 171 GHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLLGERQRFYKLVDPRLE 350 G +T K+D+++FG+ L EMM+ N N + + + + + +Y + R Sbjct: 222 GVITDKADIFAFGLTLWEMMT-LSIPHINLSNDDDDEDKTFDESDFDDEAYYAALGTRPP 280 Query: 351 GNFSV--KGAQKAAQLARACLSRDPKARPLMSQVVEALK 461 N + QK +L C + DPK RP + +VEAL+ Sbjct: 281 INMEELDESYQKVIELFSVCTNEDPKDRPSAAHIVEALE 319
>STK25_HUMAN (O00506) Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Sterile| 20/oxidant stress-response kinase 1) (Ste20/oxidant stress response kinase 1) (SOK-1) (Ste20-like kinase) Length = 426 Score = 38.9 bits (89), Expect = 0.008 Identities = 31/127 (24%), Positives = 52/127 (40%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FG+A G + D +GT + APE + K+D++S G+ +E+ G Sbjct: 159 FGVA--GQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNS 216 Query: 252 KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 P L+ P P LEG S + + ACL++DP+ RP Sbjct: 217 DLHPMRVLFLIPKNSP-------------PTLEGQHS----KPFKEFVEACLNKDPRFRP 259 Query: 432 LMSQVVE 452 ++++ Sbjct: 260 TAKELLK 266
>MATK_MOUSE (P41242) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK) Length = 505 Score = 38.9 bits (89), Expect = 0.008 Identities = 38/131 (29%), Positives = 61/131 (46%), Gaps = 2/131 (1%) Frame = +3 Query: 72 FGLAKDGPVG-DKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSM 248 FGLAK G D + + + + APE + G +SKSDV+SFGV+L E+ S R+ Sbjct: 369 FGLAKAERKGLDSSRLPVK------WTAPEALKNGRFSSKSDVWSFGVLLWEVFSYGRA- 421 Query: 249 DKNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQ-LARACLSRDPKA 425 P + +L E + + ++ Y++ P G + L +C +P Sbjct: 422 ----PYPKMSLKEVSEAV----EKGYRMEPP--------DGCPGSVHTLMGSCWEAEPAR 465 Query: 426 RPLMSQVVEAL 458 RP ++VE L Sbjct: 466 RPPFRKIVEKL 476
>PKN1_THETN (Q8R9T6) Probable serine/threonine-protein kinase Sps1 (EC| 2.7.11.1) Length = 625 Score = 38.9 bits (89), Expect = 0.008 Identities = 20/64 (31%), Positives = 35/64 (54%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FG+A+ T+ V+GT Y +PE + ++D+YS G+VL EM++G+ + Sbjct: 153 FGIARAANGATITYTGD-VIGTAYYFSPEQAKGSIVDERTDIYSLGIVLFEMLTGKVPFE 211 Query: 252 KNRP 263 + P Sbjct: 212 GDSP 215
>MELK_HUMAN (Q14680) Maternal embryonic leucine zipper kinase (EC 2.7.11.1)| (hMELK) (Protein kinase PK38) (hPK38) Length = 651 Score = 38.9 bits (89), Expect = 0.008 Identities = 26/85 (30%), Positives = 42/85 (49%), Gaps = 9/85 (10%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVM-TGHLTSKSDVYSFGVVLLEMMSGRRSM 248 FGL P G+K + G+ YAAPE + +L S++DV+S G++L +M G Sbjct: 151 FGLCAK-PKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPF 209 Query: 249 D--------KNRPNGEHNLVEWARP 299 D K G++++ +W P Sbjct: 210 DDDNVMALYKKIMRGKYDVPKWLSP 234
>PKNB_LACLA (Q9CEF5) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 627 Score = 38.9 bits (89), Expect = 0.008 Identities = 19/60 (31%), Positives = 34/60 (56%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FG+AK T +T + G+ Y +PE + T +SD+Y+ G++L E+++G+ D Sbjct: 155 FGIAKALSETSLTQTNT-MFGSVHYLSPEQARGSNATVQSDIYAIGIILFELLTGQIPFD 213
>KS6A6_HUMAN (Q9UK32) Ribosomal protein S6 kinase alpha-6 (EC 2.7.11.1)| (S6K-alpha 6) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4) Length = 745 Score = 35.4 bits (80), Expect(2) = 0.009 Identities = 22/71 (30%), Positives = 35/71 (49%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FGL+K+ +K S GT Y APE V + +D +S+GV++ EM++G Sbjct: 217 FGLSKESVDQEKKAYS--FCGTVEYMAPEVVNRRGHSQSADWWSYGVLMFEMLTGTLPFQ 274 Query: 252 KNRPNGEHNLV 284 N N++ Sbjct: 275 GKDRNETMNMI 285 Score = 22.3 bits (46), Expect(2) = 0.009 Identities = 8/13 (61%), Positives = 10/13 (76%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 ++YRD K NILL Sbjct: 194 IVYRDLKPENILL 206
>KPCT_MOUSE (Q02111) Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)| Length = 707 Score = 35.4 bits (80), Expect(2) = 0.009 Identities = 19/56 (33%), Positives = 30/56 (53%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGR 239 FG+ K+ +GD + GT Y APE ++ D +SFGV++ EM+ G+ Sbjct: 523 FGMCKENMLGDAK--TNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLVYEMLIGQ 576 Score = 22.3 bits (46), Expect(2) = 0.009 Identities = 8/13 (61%), Positives = 10/13 (76%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 ++YRD K NILL Sbjct: 500 IVYRDLKLDNILL 512
>KPC1B_CAEEL (P34885) Protein kinase C-like 1B (EC 2.7.11.13) (PKC1B)| Length = 707 Score = 33.9 bits (76), Expect(2) = 0.009 Identities = 18/56 (32%), Positives = 32/56 (57%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGR 239 FG+ K+G +K ++++ GT Y APE + D ++ GV++ EMM+G+ Sbjct: 521 FGMCKEGI--NKDNLTSTFCGTPDYIAPEILQEMEYGVSVDWWALGVLMYEMMAGQ 574 Score = 23.9 bits (50), Expect(2) = 0.009 Identities = 11/20 (55%), Positives = 12/20 (60%) Frame = +1 Query: 1 VIYRDFKTSNILLXFGIQCK 60 VIYRD K NILL C+ Sbjct: 498 VIYRDLKLDNILLDAEGHCR 517
>SRC_MOUSE (P05480) Neuronal proto-oncogene tyrosine-protein kinase Src (EC| 2.7.10.2) (p60-Src) (c-Src) (pp60c-src) Length = 540 Score = 35.4 bits (80), Expect(2) = 0.009 Identities = 26/96 (27%), Positives = 43/96 (44%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLLGERQRF 323 + APE + G T KSDV+SFG++L E+ + R N R +L + +R Sbjct: 435 WTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVN---------REVLDQVERG 485 Query: 324 YKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 Y++ P + + L C ++P+ RP Sbjct: 486 YRMPCP-------PECPESLHDLMCQCWRKEPEERP 514 Score = 22.3 bits (46), Expect(2) = 0.009 Identities = 9/30 (30%), Positives = 19/30 (63%) Frame = +1 Query: 4 IYRDFKTSNILLXFGIQCKALXILGLPKMV 93 ++RD + +NIL+ + CK + GL +++ Sbjct: 390 VHRDLRAANILVGENLVCK-VADFGLARLI 418
>SRC_RAT (Q9WUD9) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 535 Score = 35.4 bits (80), Expect(2) = 0.009 Identities = 26/96 (27%), Positives = 43/96 (44%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLLGERQRF 323 + APE + G T KSDV+SFG++L E+ + R N R +L + +R Sbjct: 430 WTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVN---------REVLDQVERG 480 Query: 324 YKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 Y++ P + + L C ++P+ RP Sbjct: 481 YRMPCP-------PECPESLHDLMCQCWRKEPEERP 509 Score = 22.3 bits (46), Expect(2) = 0.009 Identities = 9/30 (30%), Positives = 19/30 (63%) Frame = +1 Query: 4 IYRDFKTSNILLXFGIQCKALXILGLPKMV 93 ++RD + +NIL+ + CK + GL +++ Sbjct: 385 VHRDLRAANILVGENLVCK-VADFGLARLI 413
>SRC_HUMAN (P12931) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 535 Score = 35.4 bits (80), Expect(2) = 0.009 Identities = 26/96 (27%), Positives = 43/96 (44%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLLGERQRF 323 + APE + G T KSDV+SFG++L E+ + R N R +L + +R Sbjct: 430 WTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVN---------REVLDQVERG 480 Query: 324 YKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 Y++ P + + L C ++P+ RP Sbjct: 481 YRMPCP-------PECPESLHDLMCQCWRKEPEERP 509 Score = 22.3 bits (46), Expect(2) = 0.009 Identities = 9/30 (30%), Positives = 19/30 (63%) Frame = +1 Query: 4 IYRDFKTSNILLXFGIQCKALXILGLPKMV 93 ++RD + +NIL+ + CK + GL +++ Sbjct: 385 VHRDLRAANILVGENLVCK-VADFGLARLI 413
>YRK_CHICK (Q02977) Proto-oncogene tyrosine-protein kinase Yrk (EC 2.7.10.2)| (p60-Yrk) (Yes-related kinase) Length = 535 Score = 34.7 bits (78), Expect(2) = 0.009 Identities = 15/33 (45%), Positives = 23/33 (69%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRR 242 + APE + G T KSDV+SFG++L E+++ R Sbjct: 430 WTAPEAALFGKFTIKSDVWSFGILLTELVTKGR 462 Score = 23.1 bits (48), Expect(2) = 0.009 Identities = 10/30 (33%), Positives = 19/30 (63%) Frame = +1 Query: 4 IYRDFKTSNILLXFGIQCKALXILGLPKMV 93 I+RD + +NIL+ + CK + GL +++ Sbjct: 385 IHRDLRAANILVGDNLVCK-IADFGLARLI 413
>FGR_HUMAN (P09769) Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2)| (P55-FGR) (C-FGR) Length = 529 Score = 35.0 bits (79), Expect(2) = 0.009 Identities = 15/33 (45%), Positives = 23/33 (69%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRR 242 + APE + G T KSDV+SFG++L E+++ R Sbjct: 424 WTAPEAALFGRFTIKSDVWSFGILLTELITKGR 456 Score = 22.7 bits (47), Expect(2) = 0.009 Identities = 10/30 (33%), Positives = 19/30 (63%) Frame = +1 Query: 4 IYRDFKTSNILLXFGIQCKALXILGLPKMV 93 I+RD + +NIL+ + CK + GL +++ Sbjct: 379 IHRDLRAANILVGERLACK-IADFGLARLI 407
>LCK_MOUSE (P06240) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) Length = 508 Score = 34.3 bits (77), Expect(2) = 0.009 Identities = 21/66 (31%), Positives = 34/66 (51%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLLGERQRF 323 + APE + G T KSDV+SFG++L E+++ R N E ++ +R Sbjct: 405 WTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPE---------VIQNLERG 455 Query: 324 YKLVDP 341 Y++V P Sbjct: 456 YRMVRP 461 Score = 23.5 bits (49), Expect(2) = 0.009 Identities = 10/30 (33%), Positives = 19/30 (63%) Frame = +1 Query: 4 IYRDFKTSNILLXFGIQCKALXILGLPKMV 93 I+RD + +NIL+ + CK + GL +++ Sbjct: 360 IHRDLRAANILVSDTLSCK-IADFGLARLI 388
>MELK_MOUSE (Q61846) Maternal embryonic leucine zipper kinase (EC 2.7.11.1)| (Protein kinase PK38) (mPK38) Length = 643 Score = 38.5 bits (88), Expect = 0.011 Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 9/85 (10%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVM-TGHLTSKSDVYSFGVVLLEMMSGRRSM 248 FGL P G+K + G+ YAAPE + +L S++DV+S G++L +M G Sbjct: 151 FGLCAK-PKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPF 209 Query: 249 D--------KNRPNGEHNLVEWARP 299 D K G++ + +W P Sbjct: 210 DDDNVMALYKKIMRGKYEVPKWLSP 234
>PDK1A_XENLA (Q6NU47) Serine/threonine-protein kinase pdik1l-A (EC 2.7.11.1)| Length = 339 Score = 38.5 bits (88), Expect = 0.011 Identities = 38/130 (29%), Positives = 56/130 (43%), Gaps = 11/130 (8%) Frame = +3 Query: 75 GLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDK 254 GL + P + GT Y APE V GH T+K+D+++ GV+L M+ D Sbjct: 199 GLNPEEPANVNKSFLSTACGTDFYMAPE-VWEGHYTAKADIFALGVILWAMLERITITDT 257 Query: 255 NRPNGEHNLVEWARPLLGERQRFYKLV--------DPRLEGNFSVKGA---QKAAQLARA 401 + R L G QR ++V +P+LE VK ++ QL Sbjct: 258 HTKK---------RLLGGYVQRGAQVVPVGEALLENPKLELLIPVKKKSMNRRMKQLLHQ 308 Query: 402 CLSRDPKARP 431 LS +P+ RP Sbjct: 309 MLSANPQERP 318
>PKN2_CLOPE (Q8XJL8) Probable serine/threonine protein kinase CPE1738 (EC| 2.7.11.1) Length = 685 Score = 38.5 bits (88), Expect = 0.011 Identities = 20/55 (36%), Positives = 32/55 (58%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSG 236 FG+AK H ++ VMG+ Y +PE + ++D+YS G+VL EM++G Sbjct: 152 FGIAKSMDSSTIAHTNS-VMGSAHYFSPEQAKGTYTDYRTDLYSLGIVLYEMVTG 205
>TTK_HUMAN (P33981) Dual specificity protein kinase TTK (EC 2.7.12.1)| (Phosphotyrosine picked threonine-protein kinase) (PYT) Length = 841 Score = 38.5 bits (88), Expect = 0.011 Identities = 29/130 (22%), Positives = 49/130 (37%), Gaps = 11/130 (8%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMT-----------GHLTSKSDVYSFGVVL 218 FG+A + V +GT Y PE + ++ KSDV+S G +L Sbjct: 649 FGIANQMQPDTTSVVKDSQVGTVNYMPPEAIKDMSSSRENGKSKSKISPKSDVWSLGCIL 708 Query: 219 LEMMSGRRSMDKNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLAR 398 M G+ + ++ + + + ++DP E F + + + Sbjct: 709 YYMTYGKTPFQQ---------------IINQISKLHAIIDPNHEIEFPDIPEKDLQDVLK 753 Query: 399 ACLSRDPKAR 428 CL RDPK R Sbjct: 754 CCLKRDPKQR 763
>PKND_CHLPN (Q9Z986) Serine/threonine-protein kinase pknD (EC 2.7.11.1)| Length = 932 Score = 38.5 bits (88), Expect = 0.011 Identities = 20/53 (37%), Positives = 35/53 (66%), Gaps = 1/53 (1%) Frame = +3 Query: 78 LAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKS-DVYSFGVVLLEMMS 233 ++K+ + + + R++GT Y APE ++ GH SKS D+Y+ GVVL +M++ Sbjct: 174 VSKEEVLSSRMTIPGRIVGTPDYMAPERLL-GHPASKSTDIYALGVVLYQMLT 225
>DDR1_PANTR (Q7YR43) Epithelial discoidin domain-containing receptor 1 precursor| (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (CD167a antigen) Length = 909 Score = 38.5 bits (88), Expect = 0.011 Identities = 34/125 (27%), Positives = 57/125 (45%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FG++++ GD V R + + A E ++ G T+ SDV++FGV L E++ R+ Sbjct: 781 FGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQP 840 Query: 252 KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 + E ++E A ++ R L P Q +L C SR+ + RP Sbjct: 841 FGQLTDE-QVIENAGEFFRDQGRQVYLSRP-------PACPQGLYELMLRCWSRESEQRP 892 Query: 432 LMSQV 446 SQ+ Sbjct: 893 PFSQL 897
>DDR1_HUMAN (Q08345) Epithelial discoidin domain-containing receptor 1 precursor| (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) Length = 913 Score = 38.5 bits (88), Expect = 0.011 Identities = 34/125 (27%), Positives = 57/125 (45%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FG++++ GD V R + + A E ++ G T+ SDV++FGV L E++ R+ Sbjct: 785 FGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQP 844 Query: 252 KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 + E ++E A ++ R L P Q +L C SR+ + RP Sbjct: 845 FGQLTDE-QVIENAGEFFRDQGRQVYLSRP-------PACPQGLYELMLRCWSRESEQRP 896 Query: 432 LMSQV 446 SQ+ Sbjct: 897 PFSQL 901
>MATK_RAT (P41243) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase BATK) Length = 467 Score = 38.5 bits (88), Expect = 0.011 Identities = 32/105 (30%), Positives = 51/105 (48%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLLGERQRF 323 + APE + G +SKSDV+SFGV+L E+ S R+ P + +L E + + ++ Sbjct: 350 WTAPEALKNGRFSSKSDVWSFGVLLWEVFSYGRA-----PYPKMSLKEVSEAV----EKG 400 Query: 324 YKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARPLMSQVVEAL 458 Y++ P S G L +C +P RP ++VE L Sbjct: 401 YRMEPPD-----SCPG--PVHTLMGSCWEAEPSRRPPFRKIVEKL 438
>MLTK_MOUSE (Q9ESL4) Mitogen-activated protein kinase kinase kinase MLT (EC| 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper-and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) ( Length = 802 Score = 38.5 bits (88), Expect = 0.011 Identities = 34/121 (28%), Positives = 57/121 (47%) Frame = +3 Query: 108 THVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVE 287 TH+S ++GT+ + APE + + ++ D YS+GVVL EM++ R + G V Sbjct: 162 THMS--LVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLT--REVPFKGLEGLQ--VA 215 Query: 288 WARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARPLMSQVVEALKPL 467 W L+ E+ +L P + A+L C D K RP Q++ L+ + Sbjct: 216 W---LVVEKNE--RLTIPS-------SCPRSFAELLHQCWEADAKKRPSFKQIISILESM 263 Query: 468 A 470 + Sbjct: 264 S 264
>MIPR_LYMST (Q25410) Putative molluscan insulin-related peptide(s) receptor| precursor (EC 2.7.10.1) [Contains: Putative molluscan insulin-related peptide(s) receptor alpha chain; Putative molluscan insulin-related peptide(s) receptor beta chain] Length = 1607 Score = 38.5 bits (88), Expect = 0.011 Identities = 37/147 (25%), Positives = 57/147 (38%), Gaps = 7/147 (4%) Frame = +3 Query: 45 RNTMQSSQX------FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSF 206 RN M S + FG+ +D D + M + APE + G TS SDV+S+ Sbjct: 1177 RNCMVSEERTVKIGDFGMTRDIYETDYYRKGGKGMLPVRWMAPESLKDGVFTSLSDVWSY 1236 Query: 207 GVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLLG-ERQRFYKLVDPRLEGNFSVKGAQKA 383 GVV+ EM++ A+P G + K + + Sbjct: 1237 GVVMWEMVTLA-----------------AQPYQGLSNEEVVKFISDGYIMELPENCPNEM 1279 Query: 384 AQLARACLSRDPKARPLMSQVVEALKP 464 A L + C ++ P RP ++E L P Sbjct: 1280 AYLMQHCWAKKPNQRPTFKAIIEYLLP 1306
>MLTK_HUMAN (Q9NYL2) Mitogen-activated protein kinase kinase kinase MLT (EC| 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper-and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase Length = 800 Score = 38.5 bits (88), Expect = 0.011 Identities = 34/121 (28%), Positives = 57/121 (47%) Frame = +3 Query: 108 THVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVE 287 TH+S ++GT+ + APE + + ++ D YS+GVVL EM++ R + G V Sbjct: 162 THMS--LVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLT--REVPFKGLEGLQ--VA 215 Query: 288 WARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARPLMSQVVEALKPL 467 W L+ E+ +L P + A+L C D K RP Q++ L+ + Sbjct: 216 W---LVVEKNE--RLTIPS-------SCPRSFAELLHQCWEADAKKRPSFKQIISILESM 263 Query: 468 A 470 + Sbjct: 264 S 264
>LRRK2_MOUSE (Q5S006) Leucine-rich repeat serine/threonine-protein kinase 2 (EC| 2.7.11.1) Length = 2527 Score = 35.4 bits (80), Expect(2) = 0.011 Identities = 36/113 (31%), Positives = 53/113 (46%), Gaps = 4/113 (3%) Frame = +3 Query: 132 GTYGYAAPEYVMTGHL--TSKSDVYSFGVVLLEM-MSGRRSMDKNR-PNGEHNLVEWARP 299 GT G+ APE V G++ ++DVYSFG++L ++ +G R M+ R PN L Sbjct: 2034 GTPGFRAPE-VARGNVIYNQQADVYSFGLLLHDIWTTGSRIMEGLRFPNEFDELAIQG-- 2090 Query: 300 LLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARPLMSQVVEAL 458 KL DP E + +L CL +P+ RP +QV + L Sbjct: 2091 ---------KLPDPVKE--YGCAPWPMVEKLITKCLKENPQERPTSAQVFDIL 2132 Score = 21.9 bits (45), Expect(2) = 0.011 Identities = 8/13 (61%), Positives = 10/13 (76%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 +IYRD K N+LL Sbjct: 1990 IIYRDLKPHNVLL 2002
>ARBK1_RAT (P26817) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein-coupled receptor kinase 2) Length = 689 Score = 34.3 bits (77), Expect(2) = 0.012 Identities = 18/60 (30%), Positives = 32/60 (53%), Gaps = 1/60 (1%) Frame = +3 Query: 105 KTHVSTRVMGTYGYAAPEYVMTG-HLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNL 281 K H S +GT+GY APE + G S +D +S G +L +++ G +++ +H + Sbjct: 346 KPHAS---VGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEI 402 Score = 23.1 bits (48), Expect(2) = 0.012 Identities = 9/13 (69%), Positives = 11/13 (84%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 V+YRD K +NILL Sbjct: 313 VVYRDLKPANILL 325
>ARBK1_MESAU (Q64682) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein-coupled receptor kinase 2) Length = 689 Score = 34.3 bits (77), Expect(2) = 0.012 Identities = 18/60 (30%), Positives = 32/60 (53%), Gaps = 1/60 (1%) Frame = +3 Query: 105 KTHVSTRVMGTYGYAAPEYVMTG-HLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNL 281 K H S +GT+GY APE + G S +D +S G +L +++ G +++ +H + Sbjct: 346 KPHAS---VGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEI 402 Score = 23.1 bits (48), Expect(2) = 0.012 Identities = 9/13 (69%), Positives = 11/13 (84%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 V+YRD K +NILL Sbjct: 313 VVYRDLKPANILL 325
>ARBK1_HUMAN (P25098) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein coupled receptor kinase 2) Length = 689 Score = 34.3 bits (77), Expect(2) = 0.012 Identities = 18/60 (30%), Positives = 32/60 (53%), Gaps = 1/60 (1%) Frame = +3 Query: 105 KTHVSTRVMGTYGYAAPEYVMTG-HLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNL 281 K H S +GT+GY APE + G S +D +S G +L +++ G +++ +H + Sbjct: 346 KPHAS---VGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEI 402 Score = 23.1 bits (48), Expect(2) = 0.012 Identities = 9/13 (69%), Positives = 11/13 (84%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 V+YRD K +NILL Sbjct: 313 VVYRDLKPANILL 325
>ARBK1_BOVIN (P21146) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein-coupled receptor kinase 2) Length = 689 Score = 34.3 bits (77), Expect(2) = 0.012 Identities = 18/60 (30%), Positives = 32/60 (53%), Gaps = 1/60 (1%) Frame = +3 Query: 105 KTHVSTRVMGTYGYAAPEYVMTG-HLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNL 281 K H S +GT+GY APE + G S +D +S G +L +++ G +++ +H + Sbjct: 346 KPHAS---VGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEI 402 Score = 23.1 bits (48), Expect(2) = 0.012 Identities = 9/13 (69%), Positives = 11/13 (84%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 V+YRD K +NILL Sbjct: 313 VVYRDLKPANILL 325
>ARBK2_RAT (P26819) Beta-adrenergic receptor kinase 2 (EC 2.7.11.15)| (Beta-ARK-2) (G-protein-coupled receptor kinase 3) Length = 688 Score = 34.3 bits (77), Expect(2) = 0.012 Identities = 18/60 (30%), Positives = 32/60 (53%), Gaps = 1/60 (1%) Frame = +3 Query: 105 KTHVSTRVMGTYGYAAPEYVMTGH-LTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNL 281 K H S +GT+GY APE + G S +D +S G +L +++ G +++ +H + Sbjct: 346 KPHAS---VGTHGYMAPEVLQKGTCYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEI 402 Score = 23.1 bits (48), Expect(2) = 0.012 Identities = 9/13 (69%), Positives = 11/13 (84%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 V+YRD K +NILL Sbjct: 313 VVYRDLKPANILL 325
>ARBK2_HUMAN (P35626) Beta-adrenergic receptor kinase 2 (EC 2.7.11.15)| (Beta-ARK-2) (G-protein-coupled receptor kinase 3) Length = 688 Score = 34.3 bits (77), Expect(2) = 0.012 Identities = 18/60 (30%), Positives = 32/60 (53%), Gaps = 1/60 (1%) Frame = +3 Query: 105 KTHVSTRVMGTYGYAAPEYVMTG-HLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNL 281 K H S +GT+GY APE + G S +D +S G +L +++ G +++ +H + Sbjct: 346 KPHAS---VGTHGYMAPEVLQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEI 402 Score = 23.1 bits (48), Expect(2) = 0.012 Identities = 9/13 (69%), Positives = 11/13 (84%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 V+YRD K +NILL Sbjct: 313 VVYRDLKPANILL 325
>ARBK2_BOVIN (P26818) Beta-adrenergic receptor kinase 2 (EC 2.7.11.15)| (Beta-ARK-2) (G-protein-coupled receptor kinase 3) Length = 688 Score = 34.3 bits (77), Expect(2) = 0.012 Identities = 18/60 (30%), Positives = 32/60 (53%), Gaps = 1/60 (1%) Frame = +3 Query: 105 KTHVSTRVMGTYGYAAPEYVMTG-HLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNL 281 K H S +GT+GY APE + G S +D +S G +L +++ G +++ +H + Sbjct: 346 KPHAS---VGTHGYMAPEVLQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEI 402 Score = 23.1 bits (48), Expect(2) = 0.012 Identities = 9/13 (69%), Positives = 11/13 (84%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 V+YRD K +NILL Sbjct: 313 VVYRDLKPANILL 325
>GRK6_RAT (P97711) G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK6) Length = 576 Score = 35.0 bits (79), Expect(2) = 0.012 Identities = 27/100 (27%), Positives = 41/100 (41%) Frame = +3 Query: 129 MGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLLG 308 +GT GY APE V T D ++ G +L EM++G+ + + + VE Sbjct: 346 VGTVGYMAPEVVKNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVE------- 398 Query: 309 ERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKAR 428 R K V FS + +QL ++DP R Sbjct: 399 ---RLVKEVAEEYTDRFSPQARSLCSQLP----NKDPAER 431 Score = 22.3 bits (46), Expect(2) = 0.012 Identities = 8/13 (61%), Positives = 10/13 (76%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 ++YRD K NILL Sbjct: 307 IVYRDLKPENILL 319
>HCK_MACFA (Q95M30) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 503 Score = 33.9 bits (76), Expect(2) = 0.012 Identities = 14/30 (46%), Positives = 23/30 (76%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMS 233 + APE + G T KSDV+SFG++L+E+++ Sbjct: 400 WTAPEAINFGSSTIKSDVWSFGILLMEIVT 429 Score = 23.5 bits (49), Expect(2) = 0.012 Identities = 10/30 (33%), Positives = 19/30 (63%) Frame = +1 Query: 4 IYRDFKTSNILLXFGIQCKALXILGLPKMV 93 I+RD + +NIL+ + CK + GL +++ Sbjct: 355 IHRDLRAANILVSASLVCK-IADFGLARII 383
>TESK2_MOUSE (Q8VCT9) Dual specificity testis-specific protein kinase 2 (EC| 2.7.12.1) (Testicular protein kinase 2) Length = 570 Score = 38.1 bits (87), Expect = 0.014 Identities = 32/132 (24%), Positives = 58/132 (43%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FGLA+ P V+G+ + APE + K+DV+S+G++L E+++ ++ Sbjct: 198 FGLAEKIPDASIGREKLAVVGSPFWMAPEVLRDEPYNEKADVFSYGIILCEIIARIQADP 257 Query: 252 KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 P E+ +++ F +V +F QL C + DPK RP Sbjct: 258 DYLPRTENFGLDY--------DAFQNMVGD-CPSDF--------LQLTFNCCNMDPKLRP 300 Query: 432 LMSQVVEALKPL 467 ++ + LK + Sbjct: 301 SFEEIGKTLKEI 312
>E2AK1_RAT (Q63185) Eukaryotic translation initiation factor 2-alpha kinase 1| (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Heme-controlled repressor) (HCR) (Hemin-sensitive initiation factor 2- Length = 620 Score = 38.1 bits (87), Expect = 0.014 Identities = 20/43 (46%), Positives = 27/43 (62%) Frame = +3 Query: 99 GDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEM 227 G TH S +GT YA+PE + +KSD+YS GV+LLE+ Sbjct: 481 GTPTHTSR--VGTCLYASPEQLEGSEYDAKSDMYSLGVILLEL 521
>PKNB_MYCTU (P0A5S4) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 626 Score = 38.1 bits (87), Expect = 0.014 Identities = 21/65 (32%), Positives = 34/65 (52%), Gaps = 1/65 (1%) Frame = +3 Query: 72 FGLAKD-GPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSM 248 FG+A+ G+ + V+GT Y +PE + ++SDVYS G VL E+++G Sbjct: 157 FGIARAIADSGNSVTQTAAVIGTAQYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPF 216 Query: 249 DKNRP 263 + P Sbjct: 217 TGDSP 221
>PKNB_MYCBO (P0A5S5) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 626 Score = 38.1 bits (87), Expect = 0.014 Identities = 21/65 (32%), Positives = 34/65 (52%), Gaps = 1/65 (1%) Frame = +3 Query: 72 FGLAKD-GPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSM 248 FG+A+ G+ + V+GT Y +PE + ++SDVYS G VL E+++G Sbjct: 157 FGIARAIADSGNSVTQTAAVIGTAQYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPF 216 Query: 249 DKNRP 263 + P Sbjct: 217 TGDSP 221
>E2AK1_RABIT (P33279) Eukaryotic translation initiation factor 2-alpha kinase 1| (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Heme-controlled repressor) (HCR) (Hemin-sensitive initiation factor Length = 626 Score = 38.1 bits (87), Expect = 0.014 Identities = 18/43 (41%), Positives = 27/43 (62%) Frame = +3 Query: 99 GDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEM 227 G++ T +GT YA+PE + +KSD+YS GV+LLE+ Sbjct: 476 GERAPTHTSRVGTCLYASPEQLEGSEYDAKSDMYSVGVILLEL 518
>CTR1_ARATH (Q05609) Serine/threonine-protein kinase CTR1 (EC 2.7.11.1)| Length = 821 Score = 38.1 bits (87), Expect = 0.014 Identities = 31/117 (26%), Positives = 52/117 (44%) Frame = +3 Query: 117 STRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWAR 296 S GT + APE + KSDVYSFGV+L E+ + ++ P A+ Sbjct: 708 SKSAAGTPEWMAPEVLRDEPSNEKSDVYSFGVILWELATLQQPWGNLNP---------AQ 758 Query: 297 PLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARPLMSQVVEALKPL 467 + + +L PR N + + A + C + +P RP + +++ L+PL Sbjct: 759 VVAAVGFKCKRLEIPR---NLN----PQVAAIIEGCWTNEPWKRPSFATIMDLLRPL 808
>FUSED_DROME (P23647) Serine/threonine-protein kinase fused (EC 2.7.11.1)| Length = 805 Score = 38.1 bits (87), Expect = 0.014 Identities = 21/56 (37%), Positives = 32/56 (57%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGR 239 FGLA++ +G THV T + GT Y APE + +D++S G + E M+G+ Sbjct: 144 FGLARNMTLG--THVLTSIKGTPLYMAPELLAEQPYDHHADMWSLGCIAYESMAGQ 197
>KCCS_MALDO (Q07250) Calcium/calmodulin-dependent serine/threonine-protein| kinase (EC 2.7.11.17) Length = 415 Score = 38.1 bits (87), Expect = 0.014 Identities = 20/55 (36%), Positives = 33/55 (60%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSG 236 FGL+ V + T + G+ Y +PE + G +TSKSD+++ GV+L ++SG Sbjct: 195 FGLSS---VEEFTDPVVGLFGSIDYVSPEALSQGQVTSKSDMWALGVILYILLSG 246
>SSK22_YEAST (P25390) Serine/threonine-protein kinase SSK22 (EC 2.7.11.1) (MAP| kinase kinase kinase SSK22) (Suppressor of sensor kinase 22) Length = 1331 Score = 34.3 bits (77), Expect(2) = 0.014 Identities = 20/51 (39%), Positives = 28/51 (54%), Gaps = 3/51 (5%) Frame = +3 Query: 99 GDKTHVSTRVMGTYGYAAPEYVMTGHLTSK---SDVYSFGVVLLEMMSGRR 242 G +T +MGT Y APE + + K DV++ G V+LEM +GRR Sbjct: 1200 GVETKSLNEMMGTPMYMAPETISGSAVKGKLGADDVWALGCVVLEMATGRR 1250 Score = 22.7 bits (47), Expect(2) = 0.014 Identities = 9/15 (60%), Positives = 11/15 (73%) Frame = +1 Query: 1 VIYRDFKTSNILLXF 45 V++RD K NILL F Sbjct: 1154 VVHRDIKPENILLDF 1168
>M3KSL_DROME (Q95UN8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase) (dMLK) (Protein slipper) Length = 1161 Score = 34.3 bits (77), Expect(2) = 0.015 Identities = 14/35 (40%), Positives = 23/35 (65%) Frame = +3 Query: 132 GTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSG 236 GTY + PE + + SDV+S+GV+L E+++G Sbjct: 307 GTYAWMPPEVISVSTYSKFSDVWSYGVLLWELITG 341 Score = 22.7 bits (47), Expect(2) = 0.015 Identities = 8/18 (44%), Positives = 14/18 (77%) Frame = +1 Query: 1 VIYRDFKTSNILLXFGIQ 54 +I+RD K+SN+L+ I+ Sbjct: 260 IIHRDLKSSNVLIYEAIE 277
>PKH1_YEAST (Q03407) Serine/threonine-protein kinase PKH1 (EC 2.7.11.1)| (3-phosphoinositide-dependent protein kinase 1) Length = 766 Score = 35.4 bits (80), Expect(2) = 0.015 Identities = 27/118 (22%), Positives = 49/118 (41%) Frame = +3 Query: 93 PVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGE 272 P D S +GT Y +PE + + S+ D+++FG +L +M++G+ Sbjct: 286 PYFDLYAKSKSFVGTAEYVSPELLNDNYTDSRCDIWAFGCILYQMLAGKPPF-------- 337 Query: 273 HNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARPLMSQV 446 E F K++ +++ F+ Q L + L RDP R + Q+ Sbjct: 338 --------KAANEYLTFQKVM--KIQYAFTAGFPQIVKDLVKKLLVRDPNDRLTIKQI 385 Score = 21.6 bits (44), Expect(2) = 0.015 Identities = 9/20 (45%), Positives = 13/20 (65%) Frame = +1 Query: 1 VIYRDFKTSNILLXFGIQCK 60 +I+RD K NILL ++ K Sbjct: 245 IIHRDIKPENILLDKNMKVK 264
>KPCE_RAT (P09216) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 737 Score = 33.9 bits (76), Expect(2) = 0.015 Identities = 19/56 (33%), Positives = 30/56 (53%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGR 239 FG+ K+G + T +T GT Y APE + D ++ GV++ EMM+G+ Sbjct: 551 FGMCKEGILNGVT--TTTFCGTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQ 604 Score = 23.1 bits (48), Expect(2) = 0.015 Identities = 10/13 (76%), Positives = 10/13 (76%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 VIYRD K NILL Sbjct: 528 VIYRDLKLDNILL 540
>GPRK2_DROME (P32866) G protein-coupled receptor kinase 2 (EC 2.7.11.16)| Length = 714 Score = 35.4 bits (80), Expect(2) = 0.015 Identities = 23/55 (41%), Positives = 30/55 (54%) Frame = +3 Query: 75 GLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGR 239 GLA + P G+ V RV GT GY APE + D +SFG +L EM+ G+ Sbjct: 455 GLAVEIPEGEM--VRGRV-GTVGYMAPEVIDNEKYAFSPDWFSFGCLLYEMIEGQ 506 Score = 21.6 bits (44), Expect(2) = 0.015 Identities = 8/13 (61%), Positives = 10/13 (76%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 ++YRD K NILL Sbjct: 431 IVYRDCKPENILL 443
>KPCD_HUMAN (Q05655) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 676 Score = 34.7 bits (78), Expect(2) = 0.015 Identities = 20/56 (35%), Positives = 30/56 (53%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGR 239 FG+ K+ G+ ++ GT Y APE + T D +SFGV+L EM+ G+ Sbjct: 492 FGMCKENIFGESR--ASTFCGTPDYIAPEILQGLKYTFSVDWWSFGVLLYEMLIGQ 545 Score = 22.3 bits (46), Expect(2) = 0.015 Identities = 8/13 (61%), Positives = 10/13 (76%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 +IYRD K N+LL Sbjct: 469 IIYRDLKLDNVLL 481
>GRK4_RAT (P70507) G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK4) Length = 575 Score = 34.7 bits (78), Expect(2) = 0.015 Identities = 32/118 (27%), Positives = 51/118 (43%) Frame = +3 Query: 75 GLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDK 254 GLA + P G+ V RV GT GY APE + T D + G ++ EM++G K Sbjct: 331 GLALEIPEGEM--VRGRV-GTVGYMAPEIISHEKYTFSPDWWGLGCLIYEMIAGHSPFRK 387 Query: 255 NRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKAR 428 + + N E R + E + +S + ++ A + L++DP R Sbjct: 388 YKE--KVNREEMERRVKTETE------------EYSERFSENAKSICSMLLTKDPSKR 431 Score = 22.3 bits (46), Expect(2) = 0.015 Identities = 8/13 (61%), Positives = 10/13 (76%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 ++YRD K NILL Sbjct: 307 IVYRDLKPENILL 319
>ERK1_CANAL (P28869) Extracellular signal-regulated kinase 1 (EC 2.7.11.24)| (ERK1) (MAP kinase 1) (MAPK 1) Length = 417 Score = 35.8 bits (81), Expect(2) = 0.015 Identities = 23/58 (39%), Positives = 31/58 (53%), Gaps = 2/58 (3%) Frame = +3 Query: 72 FGLAKD-GPVGDKTHVSTRVMGTYGYAAPEYVMT-GHLTSKSDVYSFGVVLLEMMSGR 239 FGLA+ D T + T Y APE ++T T+ DV+S G +L EM+SGR Sbjct: 211 FGLARSIASQEDNYGFMTEYVATRWYRAPEIMLTFQEYTTAIDVWSVGCILAEMLSGR 268 Score = 21.2 bits (43), Expect(2) = 0.015 Identities = 8/13 (61%), Positives = 11/13 (84%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 V++RD K SN+LL Sbjct: 188 VLHRDLKPSNLLL 200
>MATK_HUMAN (P42679) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase) Length = 507 Score = 37.7 bits (86), Expect = 0.018 Identities = 25/59 (42%), Positives = 34/59 (57%), Gaps = 1/59 (1%) Frame = +3 Query: 72 FGLAKDGPVG-DKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRS 245 FGLAK G D + + + + APE + G TSKSDV+SFGV+L E+ S R+ Sbjct: 371 FGLAKAERKGLDSSRLPVK------WTAPEALKHGKFTSKSDVWSFGVLLWEVFSYGRA 423
>YR831_MIMIV (Q7T6Y2) Putative serine/threonine-protein kinase/receptor R831| precursor (EC 2.7.11.1) Length = 1624 Score = 37.7 bits (86), Expect = 0.018 Identities = 28/110 (25%), Positives = 49/110 (44%), Gaps = 1/110 (0%) Frame = +3 Query: 132 GTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSM-DKNRPNGEHNLVEWARPLLG 308 GT + APE + K+DV+SFGVV+ E+++G+ + N +++E RP++ Sbjct: 1522 GTPCWTAPEVIRGEKYCEKADVFSFGVVMWEVLTGKEPFAECNFMKVSLDILEGGRPIIP 1581 Query: 309 ERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARPLMSQVVEAL 458 + A+L + C RP M++VV+ L Sbjct: 1582 S------------------DCPHEFAKLIKKCWHAKAHKRPTMTEVVQQL 1613 Score = 33.9 bits (76), Expect = 0.26 Identities = 19/56 (33%), Positives = 30/56 (53%), Gaps = 2/56 (3%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSK--SDVYSFGVVLLEMMS 233 FGL K DK + ++GT + APE + +DVYSFG++L E+++ Sbjct: 927 FGLTKVKSELDKKKTNDNIIGTIHWIAPEILNDSTEVDYILADVYSFGIILWELLT 982
>PKN1_COREF (Q8FUI5) Probable serine/threonine protein kinase CE0033 (EC| 2.7.11.1) Length = 660 Score = 37.7 bits (86), Expect = 0.018 Identities = 23/67 (34%), Positives = 36/67 (53%), Gaps = 3/67 (4%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTR---VMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRR 242 FG+A+ + D T T+ V+GT Y +PE ++SDVY+ G VL E+++GR Sbjct: 155 FGIAR--ALDDSTSAMTQTAAVIGTAQYLSPEQARGKPADARSDVYAAGCVLYELVTGRP 212 Query: 243 SMDKNRP 263 + P Sbjct: 213 PFEGESP 219
>KIT_MOUSE (P05532) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 975 Score = 37.7 bits (86), Expect = 0.018 Identities = 35/133 (26%), Positives = 54/133 (40%), Gaps = 3/133 (2%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FGLA+D V + APE + + T +SDV+S+G+ L E+ S Sbjct: 809 FGLARDIRNDSNYVVKGNARLPVKWMAPESIFSCVYTFESDVWSYGIFLWELFS------ 862 Query: 252 KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQL---ARACLSRDPK 422 L P + +FYK++ EG V A++ + C DP Sbjct: 863 ---------LGSSPYPGMPVDSKFYKMIK---EGFRMVSPEHAPAEMYDVMKTCWDADPL 910 Query: 423 ARPLMSQVVEALK 461 RP QVV+ ++ Sbjct: 911 KRPTFKQVVQLIE 923
>YSK4_HUMAN (Q56UN5) SPS1/STE20-related protein kinase YSK4 (EC 2.7.11.1)| (Regulated in COPD, protein kinase) Length = 1328 Score = 37.7 bits (86), Expect = 0.018 Identities = 36/128 (28%), Positives = 57/128 (44%), Gaps = 3/128 (2%) Frame = +3 Query: 78 LAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGR---RSM 248 LA G G + + + GT + APE + KSD++S G + EM +G+ SM Sbjct: 1211 LAWAGLNGTHSDMLKSMHGTPYWMAPEVINESGYGRKSDIWSIGCTVFEMATGKPPLASM 1270 Query: 249 DKNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKAR 428 D+ A +G ++ + P L +FS + AA R CL+RD R Sbjct: 1271 DRMA----------AMFYIGA----HRGLMPPLPDHFS----ENAADFVRMCLTRDQHER 1312 Query: 429 PLMSQVVE 452 P Q+++ Sbjct: 1313 PSALQLLK 1320
>KPC2_CAEEL (P90980) Protein kinase C-like 2 (EC 2.7.11.13) (PKC2)| Length = 682 Score = 37.7 bits (86), Expect = 0.018 Identities = 20/60 (33%), Positives = 32/60 (53%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FG+ K+ GD T + GT Y APE ++ D +++GV+L EM++G+ D Sbjct: 491 FGMCKENIFGDAT--TKTFCGTPDYIAPEIILYQPYGKSVDWWAYGVLLFEMLAGQPPFD 548
>MOS_CHICK (P10741) Serine/threonine-protein kinase mos (EC 2.7.11.1) (Oocyte| maturation factor mos) Length = 349 Score = 37.7 bits (86), Expect = 0.018 Identities = 31/119 (26%), Positives = 49/119 (41%), Gaps = 7/119 (5%) Frame = +3 Query: 132 GTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNLVEWARPLLGE 311 GTY + APE + +T+K+D+YSF + L + +V +P LGE Sbjct: 245 GTYTHRAPELLKGERVTAKADIYSFAITLWQ------------------IVMREQPYLGE 286 Query: 312 RQRF------YKLVDPRLEGNFSVKG-AQKAAQLARACLSRDPKARPLMSQVVEALKPL 467 RQ Y L P F Q+ + C D + R +Q++ +L+ L Sbjct: 287 RQYVLYAVVAYNLRPPLAAAIFHESAVGQRLRSIISCCWKADVEERLSAAQLLPSLRAL 345
>KS6AA_CHICK (P18652) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 752 Score = 33.9 bits (76), Expect(2) = 0.019 Identities = 20/55 (36%), Positives = 31/55 (56%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSG 236 FGL+K+ +K S GT Y APE V + +D +S+GV++ EM++G Sbjct: 224 FGLSKEAIDHEKKAYS--FCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTG 276 Score = 22.7 bits (47), Expect(2) = 0.019 Identities = 9/13 (69%), Positives = 10/13 (76%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 +IYRD K NILL Sbjct: 201 IIYRDLKPENILL 213
>KS6A1_HUMAN (Q15418) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 33.9 bits (76), Expect(2) = 0.019 Identities = 20/55 (36%), Positives = 31/55 (56%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSG 236 FGL+K+ +K S GT Y APE V + +D +S+GV++ EM++G Sbjct: 206 FGLSKEAIDHEKKAYS--FCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTG 258 Score = 22.7 bits (47), Expect(2) = 0.019 Identities = 9/13 (69%), Positives = 10/13 (76%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 +IYRD K NILL Sbjct: 183 IIYRDLKPENILL 195
>KS6AA_XENLA (P10665) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 733 Score = 33.9 bits (76), Expect(2) = 0.019 Identities = 20/55 (36%), Positives = 31/55 (56%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSG 236 FGL+K+ +K S GT Y APE V + +D +S+GV++ EM++G Sbjct: 206 FGLSKEAIDHEKKAYS--FCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTG 258 Score = 22.7 bits (47), Expect(2) = 0.019 Identities = 9/13 (69%), Positives = 10/13 (76%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 +IYRD K NILL Sbjct: 183 IIYRDLKPENILL 195
>ARBK1_MOUSE (Q99MK8) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein-coupled receptor kinase 2) Length = 689 Score = 33.5 bits (75), Expect(2) = 0.019 Identities = 15/52 (28%), Positives = 29/52 (55%), Gaps = 1/52 (1%) Frame = +3 Query: 129 MGTYGYAAPEYVMTG-HLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGEHNL 281 +GT+GY APE + G S +D +S G +L +++ G +++ +H + Sbjct: 351 VGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEI 402 Score = 23.1 bits (48), Expect(2) = 0.019 Identities = 9/13 (69%), Positives = 11/13 (84%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 V+YRD K +NILL Sbjct: 313 VVYRDLKPANILL 325
>FGR_MOUSE (P14234) Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2)| (P55-FGR) (C-FGR) Length = 517 Score = 35.0 bits (79), Expect(2) = 0.020 Identities = 15/33 (45%), Positives = 23/33 (69%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRR 242 + APE + G T KSDV+SFG++L E+++ R Sbjct: 412 WTAPEAALFGRFTVKSDVWSFGILLTELITKGR 444 Score = 21.6 bits (44), Expect(2) = 0.020 Identities = 10/30 (33%), Positives = 19/30 (63%) Frame = +1 Query: 4 IYRDFKTSNILLXFGIQCKALXILGLPKMV 93 I+RD + +NIL+ + CK + GL +++ Sbjct: 367 IHRDLRAANILVGEYLICK-IADFGLARLI 395
>LYN_RAT (Q07014) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 33.1 bits (74), Expect(2) = 0.020 Identities = 16/43 (37%), Positives = 26/43 (60%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGE 272 + APE + G T KSDV+SFG++L E+++ + R N + Sbjct: 408 WTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNAD 450 Score = 23.5 bits (49), Expect(2) = 0.020 Identities = 9/30 (30%), Positives = 19/30 (63%) Frame = +1 Query: 4 IYRDFKTSNILLXFGIQCKALXILGLPKMV 93 I+RD + +N+L+ + CK + GL +++ Sbjct: 363 IHRDLRAANVLVSESLMCK-IADFGLARVI 391
>LYN_MOUSE (P25911) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 33.1 bits (74), Expect(2) = 0.020 Identities = 16/43 (37%), Positives = 26/43 (60%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGE 272 + APE + G T KSDV+SFG++L E+++ + R N + Sbjct: 408 WTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNAD 450 Score = 23.5 bits (49), Expect(2) = 0.020 Identities = 9/30 (30%), Positives = 19/30 (63%) Frame = +1 Query: 4 IYRDFKTSNILLXFGIQCKALXILGLPKMV 93 I+RD + +N+L+ + CK + GL +++ Sbjct: 363 IHRDLRAANVLVSESLMCK-IADFGLARVI 391
>LYN_HUMAN (P07948) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 33.1 bits (74), Expect(2) = 0.020 Identities = 16/43 (37%), Positives = 26/43 (60%) Frame = +3 Query: 144 YAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRPNGE 272 + APE + G T KSDV+SFG++L E+++ + R N + Sbjct: 408 WTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNAD 450 Score = 23.5 bits (49), Expect(2) = 0.020 Identities = 9/30 (30%), Positives = 19/30 (63%) Frame = +1 Query: 4 IYRDFKTSNILLXFGIQCKALXILGLPKMV 93 I+RD + +N+L+ + CK + GL +++ Sbjct: 363 IHRDLRAANVLVSESLMCK-IADFGLARVI 391
>MAPK_FUSSO (Q00859) Mitogen-activated protein kinase (EC 2.7.11.24) (FsMAPK)| Length = 355 Score = 35.4 bits (80), Expect(2) = 0.020 Identities = 22/58 (37%), Positives = 31/58 (53%), Gaps = 2/58 (3%) Frame = +3 Query: 72 FGLAKDGPVG-DKTHVSTRVMGTYGYAAPEYVMT-GHLTSKSDVYSFGVVLLEMMSGR 239 FGLA+ D + T + T Y APE ++T T DV+S G +L EM+SG+ Sbjct: 166 FGLARSAASQEDNSGFMTEYVATRWYRAPEIMLTFKEYTKAIDVWSVGCILAEMLSGK 223 Score = 21.2 bits (43), Expect(2) = 0.020 Identities = 8/13 (61%), Positives = 11/13 (84%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 V++RD K SN+LL Sbjct: 143 VLHRDLKPSNLLL 155
>LOK_DROME (O61267) Ovarian-specific serine/threonine-protein kinase Lok (EC| 2.7.11.1) (Protein loki) (dMNK) Length = 476 Score = 37.4 bits (85), Expect = 0.024 Identities = 38/138 (27%), Positives = 56/138 (40%), Gaps = 3/138 (2%) Frame = +3 Query: 51 TMQSSQXFGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGH---LTSKSDVYSFGVVLL 221 T+ FGL+K K V + GT Y APE ++TG T K D++S GVVL Sbjct: 318 TLLKVSDFGLSK---FVQKDSVMRTLCGTPLYVAPEVLITGGREAYTKKVDIWSLGVVLF 374 Query: 222 EMMSGRRSMDKNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARA 401 +SG ++ R G +K V +Q+A L Sbjct: 375 TCLSGTLPFSDEYGTPAAQQIKKGRFAYGHPS--WKSV------------SQRAKLLINQ 420 Query: 402 CLSRDPKARPLMSQVVEA 455 L DP+ RP + V+++ Sbjct: 421 MLIVDPERRPSIDDVLQS 438
>DLL3_XENLA (P54655) Homeobox protein DLL-3 (XDLL-3)| Length = 289 Score = 37.4 bits (85), Expect = 0.024 Identities = 25/102 (24%), Positives = 42/102 (41%) Frame = -2 Query: 444 LGSSEAGLWGPGSGMRVPIVQPSGHL*PRNSPPGEGRLTCRTVVSPLGGGAPTPQGCARH 265 L ++ +W ++ + +G L P +SP + C + SP+ PQG +R Sbjct: 176 LTQTQVKIWFQNKRSKIKKIMKNGELPPEHSPSSSDPMACNSPQSPV---VWEPQGSSRS 232 Query: 264 LGGSCPLTFVPTSSQAAPHQSYRRHSLMSNGLS*HTLELHNH 139 L + P S ++P SY +S + H L NH Sbjct: 233 LSHHPHVHSHPQPSSSSPASSYLENSGVWYPTGTHLQNLQNH 274
>ROR1_DROME (Q24488) Tyrosine-protein kinase transmembrane receptor Ror| precursor (EC 2.7.10.1) (dRor) Length = 685 Score = 37.4 bits (85), Expect = 0.024 Identities = 20/54 (37%), Positives = 32/54 (59%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMS 233 FGL++D D V ++ + + E ++ G T++SDV+SFGVVL E+ S Sbjct: 558 FGLSRDIYSSDYYRVQSKSLLPVRWMPSESILYGKFTTESDVWSFGVVLWEIYS 611
>KIT_BOVIN (P43481) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 977 Score = 37.4 bits (85), Expect = 0.024 Identities = 30/130 (23%), Positives = 49/130 (37%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FGLA+D V + APE + T +SDV+S+G+ L E+ S Sbjct: 812 FGLARDIKNDSNYVVKGNARLPVKWMAPESIFNCVYTFESDVWSYGIFLWELFS------ 865 Query: 252 KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 L P + +FYK++ + + + C DP RP Sbjct: 866 ---------LGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRP 916 Query: 432 LMSQVVEALK 461 Q+V+ ++ Sbjct: 917 TFKQIVQLIE 926
>M3K13_PONPY (Q5R8X7) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) Length = 966 Score = 37.4 bits (85), Expect = 0.024 Identities = 20/55 (36%), Positives = 33/55 (60%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSG 236 FG +K+ + DK+ GT + APE + ++ K D++SFGVVL E+++G Sbjct: 298 FGTSKE--LSDKS-TKMSFAGTVAWLAPEVIRNEPVSEKVDIWSFGVVLWELLTG 349
>M3K13_HUMAN (O43283) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase) Length = 966 Score = 37.4 bits (85), Expect = 0.024 Identities = 20/55 (36%), Positives = 33/55 (60%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSG 236 FG +K+ + DK+ GT + APE + ++ K D++SFGVVL E+++G Sbjct: 298 FGTSKE--LSDKS-TKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTG 349
>M3K12_RAT (Q63796) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 37.4 bits (85), Expect = 0.024 Identities = 20/55 (36%), Positives = 33/55 (60%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSG 236 FG +K+ + DK+ GT + APE + ++ K D++SFGVVL E+++G Sbjct: 288 FGTSKE--LSDKS-TKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTG 339
>M3K12_MOUSE (Q60700) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 37.4 bits (85), Expect = 0.024 Identities = 20/55 (36%), Positives = 33/55 (60%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSG 236 FG +K+ + DK+ GT + APE + ++ K D++SFGVVL E+++G Sbjct: 288 FGTSKE--LSDKS-TKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTG 339
>KIT_FELCA (Q28889) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 978 Score = 37.4 bits (85), Expect = 0.024 Identities = 30/130 (23%), Positives = 49/130 (37%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FGLA+D V + APE + T +SDV+S+G+ L E+ S Sbjct: 812 FGLARDIKNDSNYVVKGNARLPVKWMAPESIFNCVYTFESDVWSYGIFLWELFS------ 865 Query: 252 KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 L P + +FYK++ + + + C DP RP Sbjct: 866 ---------LGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRP 916 Query: 432 LMSQVVEALK 461 Q+V+ ++ Sbjct: 917 TFKQIVQLIE 926
>KIT_CAPHI (Q28317) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 978 Score = 37.4 bits (85), Expect = 0.024 Identities = 30/130 (23%), Positives = 49/130 (37%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FGLA+D V + APE + T +SDV+S+G+ L E+ S Sbjct: 813 FGLARDIKNDSNYVVKGNARLPVKWMAPESIFNCVYTFESDVWSYGIFLWELFS------ 866 Query: 252 KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 L P + +FYK++ + + + C DP RP Sbjct: 867 ---------LGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRP 917 Query: 432 LMSQVVEALK 461 Q+V+ ++ Sbjct: 918 TFKQIVQLIE 927
>STE11_YEAST (P23561) Serine/threonine-protein kinase STE11 (EC 2.7.11.1)| Length = 738 Score = 37.4 bits (85), Expect = 0.024 Identities = 18/57 (31%), Positives = 34/57 (59%), Gaps = 1/57 (1%) Frame = +3 Query: 72 FGLAKD-GPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGR 239 FG++K P+ K + + G+ + +PE V T+K+D++S G V++EM +G+ Sbjct: 619 FGISKKLSPLNKKQNKRASLQGSVFWMSPEVVKQTATTAKADIWSTGCVVIEMFTGK 675
>KIT_HUMAN (P10721) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen) Length = 976 Score = 37.4 bits (85), Expect = 0.024 Identities = 30/130 (23%), Positives = 49/130 (37%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FGLA+D V + APE + T +SDV+S+G+ L E+ S Sbjct: 811 FGLARDIKNDSNYVVKGNARLPVKWMAPESIFNCVYTFESDVWSYGIFLWELFS------ 864 Query: 252 KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 L P + +FYK++ + + + C DP RP Sbjct: 865 ---------LGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRP 915 Query: 432 LMSQVVEALK 461 Q+V+ ++ Sbjct: 916 TFKQIVQLIE 925
>KIT_FSVHZ (P04048) Tyrosine-protein kinase transforming protein kit (EC| 2.7.10.1) Length = 370 Score = 37.4 bits (85), Expect = 0.024 Identities = 30/130 (23%), Positives = 49/130 (37%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FGLA+D V + APE + T +SDV+S+G+ L E+ S Sbjct: 249 FGLARDIKNDSNYVVKGNARLPVKWMAPESIFNCVYTFESDVWSYGIFLWELFS------ 302 Query: 252 KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 L P + +FYK++ + + + C DP RP Sbjct: 303 ---------LGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRP 353 Query: 432 LMSQVVEALK 461 Q+V+ ++ Sbjct: 354 TFKQIVQLIE 363
>M3K12_HUMAN (Q12852) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 859 Score = 37.4 bits (85), Expect = 0.024 Identities = 20/55 (36%), Positives = 33/55 (60%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSG 236 FG +K+ + DK+ GT + APE + ++ K D++SFGVVL E+++G Sbjct: 255 FGTSKE--LSDKS-TKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTG 306
>KIT_CANFA (O97799) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 975 Score = 37.4 bits (85), Expect = 0.024 Identities = 30/130 (23%), Positives = 49/130 (37%) Frame = +3 Query: 72 FGLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMD 251 FGLA+D V + APE + T +SDV+S+G+ L E+ S Sbjct: 810 FGLARDIKNDSNYVVKGNARLPVKWMAPESIFNCVYTFESDVWSYGIFLWELFS------ 863 Query: 252 KNRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKARP 431 L P + +FYK++ + + + C DP RP Sbjct: 864 ---------LGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRP 914 Query: 432 LMSQVVEALK 461 Q+V+ ++ Sbjct: 915 TFKQIVQLIE 924
>ULK1_MOUSE (O70405) Serine/threonine-protein kinase ULK1 (EC 2.7.11.1)| (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1) Length = 1051 Score = 35.4 bits (80), Expect(2) = 0.024 Identities = 13/50 (26%), Positives = 29/50 (58%) Frame = +3 Query: 114 VSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRP 263 ++ + G+ Y APE +M+ H K+D++S G ++ + ++G+ + P Sbjct: 177 MAATLCGSPMYMAPEVIMSQHYDGKADLWSIGTIVYQCLTGKAPFQASSP 226 Score = 20.8 bits (42), Expect(2) = 0.024 Identities = 8/13 (61%), Positives = 10/13 (76%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 +I+RD K NILL Sbjct: 134 IIHRDLKPQNILL 146
>ULK1_HUMAN (O75385) Serine/threonine-protein kinase ULK1 (EC 2.7.11.1)| (Unc-51-like kinase 1) Length = 1050 Score = 35.4 bits (80), Expect(2) = 0.024 Identities = 13/50 (26%), Positives = 29/50 (58%) Frame = +3 Query: 114 VSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDKNRP 263 ++ + G+ Y APE +M+ H K+D++S G ++ + ++G+ + P Sbjct: 177 MAATLCGSPMYMAPEVIMSQHYDGKADLWSIGTIVYQCLTGKAPFQASSP 226 Score = 20.8 bits (42), Expect(2) = 0.024 Identities = 8/13 (61%), Positives = 10/13 (76%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 +I+RD K NILL Sbjct: 134 IIHRDLKPQNILL 146
>GRK4_MOUSE (O70291) G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK4) Length = 574 Score = 33.9 bits (76), Expect(2) = 0.025 Identities = 32/118 (27%), Positives = 50/118 (42%) Frame = +3 Query: 75 GLAKDGPVGDKTHVSTRVMGTYGYAAPEYVMTGHLTSKSDVYSFGVVLLEMMSGRRSMDK 254 GLA + P G+ V RV GT GY APE + T D + G ++ EM++G K Sbjct: 331 GLAMEVPEGEM--VRGRV-GTVGYMAPEIINHEKYTFSPDWWGLGCLIYEMIAGHSPFRK 387 Query: 255 NRPNGEHNLVEWARPLLGERQRFYKLVDPRLEGNFSVKGAQKAAQLARACLSRDPKAR 428 + + N E R + E + +S + ++ A + L +DP R Sbjct: 388 YKE--KVNREELERRVKNETE------------EYSERFSEDAKSICSMLLIKDPSKR 431 Score = 22.3 bits (46), Expect(2) = 0.025 Identities = 8/13 (61%), Positives = 10/13 (76%) Frame = +1 Query: 1 VIYRDFKTSNILL 39 ++YRD K NILL Sbjct: 307 IVYRDLKPENILL 319 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 82,669,802 Number of Sequences: 219361 Number of extensions: 2033081 Number of successful extensions: 8051 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 6908 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 7895 length of database: 80,573,946 effective HSP length: 104 effective length of database: 57,760,402 effective search space used: 3754426130 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
