>FAAA_RAT (P25093) Fumarylacetoacetase (EC 3.7.1.2) (Fumarylacetoacetate|
           hydrolase) (Beta-diketonase) (FAA)
          Length = 419

 Score =  278 bits (710), Expect = 1e-74
 Identities = 130/221 (58%), Positives = 163/221 (73%), Gaps = 1/221 (0%)
 Frame = +1

Query: 34  LFDGPLLSASP-CFRQETLNMFLGLGRPAWKEARATLQKILSADEPVLRDNEALRKNCLV 210
           LF GP+LS     F + TLN F+GLG+ AWKEARA+LQ +LSA +  LRD++ LR+    
Sbjct: 49  LFTGPVLSKHQHVFDETTLNSFMGLGQAAWKEARASLQNLLSASQAQLRDDKELRQRAFT 108

Query: 211 PMSDVEMLLPITVGDYTDFFCSVHHARNCGFIFRGPQTPVNPNWFHLPVGYHGRASSVII 390
             +   M LP T+GDYTDF+ S+ HA N G +FRG +  + PNW HLPVGYHGRASSV++
Sbjct: 109 SQASATMHLPATIGDYTDFYSSLQHATNVGIMFRGKENALLPNWLHLPVGYHGRASSVVV 168

Query: 391 SGTDIIRPRGQGHPTGSSQPYFGPSQKLDFELEMAAIVGPGNELGKPIDIADAEDHIFGL 570
           SGT I RP GQ  P  S  P +G S++LD ELEMA  VGPGN  G+PI I+ A++HIFG+
Sbjct: 169 SGTPIRRPMGQMRPDNSKPPVYGASKRLDMELEMAFFVGPGNRFGEPIPISKAQEHIFGM 228

Query: 571 VVMNDWSARDIQAWETIPLGPFLGKSFSTSVSPWIVTLDAL 693
           V+MNDWSARDIQ WE +PLGPFLGKSF T++SPW+V +DAL
Sbjct: 229 VLMNDWSARDIQQWEYVPLGPFLGKSFGTTISPWVVPMDAL 269

>FAAA_MOUSE (P35505) Fumarylacetoacetase (EC 3.7.1.2) (Fumarylacetoacetate|
           hydrolase) (Beta-diketonase) (FAA)
          Length = 419

 Score =  270 bits (690), Expect = 3e-72
 Identities = 128/221 (57%), Positives = 158/221 (71%), Gaps = 1/221 (0%)
 Frame = +1

Query: 34  LFDGPLLSASP-CFRQETLNMFLGLGRPAWKEARATLQKILSADEPVLRDNEALRKNCLV 210
           LF GP LS     F + TLN F+GLG+ AWKEARA+LQ +LSA +  LRD++ LR+    
Sbjct: 49  LFTGPALSKHQHVFDETTLNNFMGLGQAAWKEARASLQNLLSASQARLRDDKELRQRAFT 108

Query: 211 PMSDVEMLLPITVGDYTDFFCSVHHARNCGFIFRGPQTPVNPNWFHLPVGYHGRASSVII 390
             +   M LP T+GDYTDF+ S  HA N G +FRG +  + PNW HLPVGYHGRASS+++
Sbjct: 109 SQASATMHLPATIGDYTDFYSSRQHATNVGIMFRGKENALLPNWLHLPVGYHGRASSIVV 168

Query: 391 SGTDIIRPRGQGHPTGSSQPYFGPSQKLDFELEMAAIVGPGNELGKPIDIADAEDHIFGL 570
           SGT I RP GQ  P  S  P +G  + LD ELEMA  VGPGN  G+PI I+ A +HIFG+
Sbjct: 169 SGTPIRRPMGQMRPDNSKPPVYGACRLLDMELEMAFFVGPGNRFGEPIPISKAHEHIFGM 228

Query: 571 VVMNDWSARDIQAWETIPLGPFLGKSFSTSVSPWIVTLDAL 693
           V+MNDWSARDIQ WE +PLGPFLGKSF T++SPW+V +DAL
Sbjct: 229 VLMNDWSARDIQQWEYVPLGPFLGKSFGTTISPWVVPMDAL 269

>FAAA_HUMAN (P16930) Fumarylacetoacetase (EC 3.7.1.2) (Fumarylacetoacetate|
           hydrolase) (Beta-diketonase) (FAA)
          Length = 419

 Score =  269 bits (688), Expect = 5e-72
 Identities = 130/221 (58%), Positives = 156/221 (70%), Gaps = 1/221 (0%)
 Frame = +1

Query: 34  LFDGPLLSA-SPCFRQETLNMFLGLGRPAWKEARATLQKILSADEPVLRDNEALRKNCLV 210
           LF GP+LS     F Q TLN F+GLG+ AWKEAR  LQ +LS  +  LRD+  LRK   +
Sbjct: 49  LFTGPVLSKHQDVFNQPTLNSFMGLGQAAWKEARVFLQNLLSVSQARLRDDTELRKCAFI 108

Query: 211 PMSDVEMLLPITVGDYTDFFCSVHHARNCGFIFRGPQTPVNPNWFHLPVGYHGRASSVII 390
             +   M LP T+GDYTDF+ S  HA N G +FR  +  + PNW HLPVGYHGRASSV++
Sbjct: 109 SQASATMHLPATIGDYTDFYSSRQHATNVGIMFRDKENALMPNWLHLPVGYHGRASSVVV 168

Query: 391 SGTDIIRPRGQGHPTGSSQPYFGPSQKLDFELEMAAIVGPGNELGKPIDIADAEDHIFGL 570
           SGT I RP GQ  P  S  P +G  + LD ELEMA  VGPGN LG+PI I+ A +HIFG+
Sbjct: 169 SGTPIRRPMGQMKPDDSKPPVYGACKLLDMELEMAFFVGPGNRLGEPIPISKAHEHIFGM 228

Query: 571 VVMNDWSARDIQAWETIPLGPFLGKSFSTSVSPWIVTLDAL 693
           V+MNDWSARDIQ WE +PLGPFLGKSF T+VSPW+V +DAL
Sbjct: 229 VLMNDWSARDIQKWEYVPLGPFLGKSFGTTVSPWVVPMDAL 269

>FAAA_EMENI (Q00770) Fumarylacetoacetase (EC 3.7.1.2) (Fumarylacetoacetate|
           hydrolase) (Beta-diketonase) (FAA)
          Length = 431

 Score =  240 bits (612), Expect = 3e-63
 Identities = 114/214 (53%), Positives = 153/214 (71%), Gaps = 6/214 (2%)
 Frame = +1

Query: 70  FRQETLNMFLGLGRPAWKEARATLQKILSADEP---VLRDNEALRKNCLVPMSDVEMLLP 240
           F++ TLN F  LGRP  ++ R  +QK+ S + P   +LRDN AL+K  L+P+S+V   LP
Sbjct: 66  FKESTLNAFAALGRPVHRQVREYIQKVFSTETPFPQILRDNAALQKEALLPLSEVTNHLP 125

Query: 241 ITVGDYTDFFCSVHHARNCGFIFRGPQTPVNPNWFHLPVGYHGRASSVIISGTDIIRPRG 420
           + +GDYTDF+  ++HA N G +FRGP   + PN+ HLPV YHGRASSV+ SGT + RP+G
Sbjct: 126 MQIGDYTDFYAGLNHAYNVGVLFRGPDNALQPNYKHLPVAYHGRASSVVTSGTPLHRPQG 185

Query: 421 Q--GHPTGSSQ-PYFGPSQKLDFELEMAAIVGPGNELGKPIDIADAEDHIFGLVVMNDWS 591
           Q   +P  + + P F P +KLD ELE+A  V   N+LG P+ I  AEDHIFG+V+MNDWS
Sbjct: 186 QILTNPAANPKLPTFSPCKKLDIELELAFFVSTPNDLGHPVHIDKAEDHIFGVVLMNDWS 245

Query: 592 ARDIQAWETIPLGPFLGKSFSTSVSPWIVTLDAL 693
           ARDIQAWE +PLGPF  K+F T+++PW+V +DAL
Sbjct: 246 ARDIQAWEYVPLGPFNAKNFGTTITPWVVLIDAL 279

>Y1656_METJA (Q59050) Hypothetical protein MJ1656|
          Length = 237

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 26/85 (30%), Positives = 46/85 (54%)
 Frame = +1

Query: 352 PVGYHGRASSVIISGTDIIRPRGQGHPTGSSQPYFGPSQKLDFELEMAAIVGPGNELGKP 531
           P+ +    S++I +   IIRPR               S+++D+E+E+A ++G   +  K 
Sbjct: 62  PIIFLKPTSAIIYNEDYIIRPR--------------ISKRVDYEVELAIVIG---KKCKN 104

Query: 532 IDIADAEDHIFGLVVMNDWSARDIQ 606
           I   +A D+I G  ++ND +ARD+Q
Sbjct: 105 IKKDEANDYIMGYTILNDVTARDLQ 129

>Y643_PYRHO (O58377) Hypothetical protein PH0643|
          Length = 230

 Score = 37.0 bits (84), Expect = 0.057
 Identities = 30/99 (30%), Positives = 48/99 (48%)
 Frame = +1

Query: 313 GPQTPVNPNWFHLPVGYHGRASSVIISGTDIIRPRGQGHPTGSSQPYFGPSQKLDFELEM 492
           G + P  P  F  P       S++I  G+ II PR               S+++D E+E+
Sbjct: 38  GSEPPEEPIIFLKP------PSALIGPGSSIILPRR--------------SKRVDHEVEL 77

Query: 493 AAIVGPGNELGKPIDIADAEDHIFGLVVMNDWSARDIQA 609
           A I+G   +  K +  + A D+I G  ++ D +ARD+QA
Sbjct: 78  AVIMG---KRAKNVPASKAFDYILGYTIILDITARDLQA 113

>Y2225_ARCFU (O28058) Hypothetical protein AF2225|
          Length = 250

 Score = 36.6 bits (83), Expect = 0.075
 Identities = 23/72 (31%), Positives = 38/72 (52%), Gaps = 11/72 (15%)
 Frame = +1

Query: 463 SQKLDFELEMAAIVGPGNELGKPIDIADAEDHIFGLVVMNDWSARDIQA----WET---- 618
           SQ++D+E E+A ++    E  + +   +A D+I G    ND +ARD+QA    W      
Sbjct: 91  SQRVDYEGELAVVIA---EDCRNVPETNAADYILGYTCFNDVTARDLQAKDGQWTRAKSF 147

Query: 619 ---IPLGPFLGK 645
               PLGP++ +
Sbjct: 148 DTFAPLGPYIAE 159

>Y1397_PYRAB (Q9UYW0) Hypothetical protein PYRAB13970|
          Length = 225

 Score = 35.4 bits (80), Expect = 0.17
 Identities = 18/49 (36%), Positives = 31/49 (63%)
 Frame = +1

Query: 463 SQKLDFELEMAAIVGPGNELGKPIDIADAEDHIFGLVVMNDWSARDIQA 609
           S+++D E+E+A I+G   +  K +    A D+I G  ++ D +ARD+QA
Sbjct: 63  SKRVDHEVELAVIIG---KRAKNVPAEKAFDYILGYTILLDITARDLQA 108

>S6A12_HUMAN (P48065) Sodium- and chloride-dependent betaine transporter|
           (Na+/Cl-betaine/GABA transporter) (BGT-1)
          Length = 614

 Score = 33.9 bits (76), Expect = 0.48
 Identities = 17/41 (41%), Positives = 21/41 (51%)
 Frame = +3

Query: 345 SFTSWLPWTGIICNHIWNRHYSTQRTRSSNRKLPTLFRSFS 467
           SFTS LPWT   CN+ WN  + T     S     T F +F+
Sbjct: 147 SFTSELPWT--TCNNFWNTEHCTDFLNHSGAGTVTPFENFT 185

>HPCE_ECOLI (P37352) Homoprotocatechuate catabolism bifunctional|
           isomerase/decarboxylase [Includes:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC
           5.3.3.10) (HHDD isomerase)
           (5-carboxymethyl-2-hydroxymuconate delta-isomerase);
           5-carboxymethyl-2-oxo-hex
          Length = 427

 Score = 32.3 bits (72), Expect = 1.4
 Identities = 17/58 (29%), Positives = 32/58 (55%), Gaps = 2/58 (3%)
 Frame = +1

Query: 433 TGSSQPYFGPS--QKLDFELEMAAIVGPGNELGKPIDIADAEDHIFGLVVMNDWSARD 600
           TG +Q    P+  + + +E E+  ++G   +  + +  ADA D++ G  V ND++ RD
Sbjct: 258 TGDNQTSVRPNNIEYMHYEAELVVVIG---KQARNVSEADAMDYVAGYTVCNDYAIRD 312

>YO23_CAEEL (P34673) Hypothetical protein ZK688.3 in chromosome III|
          Length = 214

 Score = 32.3 bits (72), Expect = 1.4
 Identities = 30/104 (28%), Positives = 44/104 (42%), Gaps = 1/104 (0%)
 Frame = +1

Query: 352 PVGYHGRASSVIISGTDIIRPRGQGHPTGSSQPYFGPSQKLDFELEMAAIVGPGNELGKP 531
           P+ +    +S I+ G  I+ P G               Q L  E+E+  ++   ++    
Sbjct: 36  PMLFVKTVNSFIVEGEPIVAPPG--------------CQNLHQEVELGVVI---SKKASR 78

Query: 532 IDIADAEDHIFGLVVMNDWSARDIQAWETIPLGP-FLGKSFSTS 660
           I  +DA D+I G  V  D +ARD Q        P FL KSF  S
Sbjct: 79  ISKSDAMDYIGGYTVALDMTARDFQDEAKKAGAPWFLAKSFDGS 122

>HPAG_ECOLI (Q46978) 4-hydroxyphenylacetate degradation bifunctional|
           isomerase/decarboxylase [Includes:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC
           5.3.3.10) (HHDD isomerase)
           (5-carboxymethyl-2-hydroxymuconate delta-isomerase);
           5-carboxymethyl-2-oxo
          Length = 429

 Score = 32.3 bits (72), Expect = 1.4
 Identities = 17/58 (29%), Positives = 32/58 (55%), Gaps = 2/58 (3%)
 Frame = +1

Query: 433 TGSSQPYFGPS--QKLDFELEMAAIVGPGNELGKPIDIADAEDHIFGLVVMNDWSARD 600
           TG +Q    P+  + + +E E+  ++G   +  + +  ADA D++ G  V ND++ RD
Sbjct: 258 TGDNQTSVRPNNIEYMHYEAELVVVIG---KQARNVSEADAMDYVAGYTVCNDYAIRD 312

>SC6A6_BOVIN (Q9MZ34) Sodium- and chloride-dependent taurine transporter|
          Length = 620

 Score = 30.8 bits (68), Expect = 4.1
 Identities = 15/33 (45%), Positives = 17/33 (51%)
 Frame = +3

Query: 345 SFTSWLPWTGIICNHIWNRHYSTQRTRSSNRKL 443
           SF S LPW    CNH WN  +  + T   NR L
Sbjct: 152 SFQSELPWAK--CNHSWNTPHCLEDTLRRNRSL 182

>GLSA_CAUCR (Q9ABF2) Glutaminase (EC 3.5.1.2)|
          Length = 306

 Score = 30.8 bits (68), Expect = 4.1
 Identities = 11/41 (26%), Positives = 24/41 (58%)
 Frame = +1

Query: 445 QPYFGPSQKLDFELEMAAIVGPGNELGKPIDIADAEDHIFG 567
           +P+FG  +  D+  ++A +  PG + G  + + D ++H+ G
Sbjct: 18  RPHFGKGKPADYIPQLATV--PGGKFGMAVRMVDGDEHVIG 56

>PAC_ARTVI (P31956) Penicillin G acylase precursor (EC 3.5.1.11) (Penicillin G|
           amidase) (Penicillin G amidohydrolase) [Contains:
           Penicillin G acylase zymogen; Penicillin G acylase alpha
           subunit; Penicillin G acylase beta subunit]
          Length = 802

 Score = 30.0 bits (66), Expect = 7.0
 Identities = 26/90 (28%), Positives = 41/90 (45%), Gaps = 3/90 (3%)
 Frame = +1

Query: 106 GRPAWKEARATLQKILSADEPVLRDNEAL---RKNCLVPMSDVEMLLPITVGDYTDFFCS 276
           G+P  + +  +LQK+ SA   V++ +E +   R+N +   S  E+ LP+ +G       S
Sbjct: 219 GKPKRESSSQSLQKLSSA---VIKASEKVGKERENFV--QSSEELGLPLKIGSNAAIVGS 273

Query: 277 VHHARNCGFIFRGPQTPVNPNWFHLPVGYH 366
              A     +F GPQ       F   VG H
Sbjct: 274 EKSATGNALLFSGPQVGFVAPGFLYEVGLH 303

>SC6A3_BOVIN (P27922) Sodium-dependent dopamine transporter (DA transporter)|
           (DAT)
          Length = 693

 Score = 29.6 bits (65), Expect = 9.1
 Identities = 13/20 (65%), Positives = 14/20 (70%)
 Frame = +3

Query: 339 LVSFTSWLPWTGIICNHIWN 398
           L SFT+ LPWT   CNH WN
Sbjct: 168 LSSFTTELPWTH--CNHSWN 185

>VP19_HHV2H (P89461) Capsid assembly and DNA maturation protein (Capsid protein|
           VP19C)
          Length = 466

 Score = 29.6 bits (65), Expect = 9.1
 Identities = 22/72 (30%), Positives = 35/72 (48%), Gaps = 1/72 (1%)
 Frame = -2

Query: 301 IHSSLHGAQNKRNPCSLPP**VEASLHHSLAQGSSSSR-PRCHATPAHQLRGFSGAWRAP 125
           I +++HGA++   P   PP     ++   LA  ++SS+ PRC A+     +     +R  
Sbjct: 352 ITNTIHGAEDMTPP---PP---NRNVDFPLAVPAASSQSPRCSASQVTNPQFVDRLYRWQ 405

Query: 124 PSTPAGPTPRTC 89
           P     PT RTC
Sbjct: 406 PDLRGRPTARTC 417


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 107,627,442
Number of Sequences: 219361
Number of extensions: 2516565
Number of successful extensions: 7179
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 6848
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7174
length of database: 80,573,946
effective HSP length: 109
effective length of database: 56,663,597
effective search space used: 6912958834
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)