ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bags30n22 |
|---|---|
| Clone Library Name | barley_pub |
>PP2CG_HUMAN (O15355) Protein phosphatase 2C isoform gamma (EC 3.1.3.16)| (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C) Length = 546 Score = 194 bits (493), Expect = 2e-49 Identities = 99/183 (54%), Positives = 131/183 (71%), Gaps = 8/183 (4%) Frame = +1 Query: 142 GPTCGSTACVAMVRNSQLVVANAGDSRCVISRNGQAYNLSRDHKPELEAERERILKAGGY 321 G G+TA VA++R QL+VANAGDSRCV+S G+A ++S DHKPE E E RI AGG Sbjct: 324 GSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGK 383 Query: 322 IQM-GRVNGTINLSRAIGDMEFKQNKFLSPDKQMLTANPDVNTVELCDDDDFLVLACDGI 498 + M GRVNG +NLSRAIGD +K+NK L P++QM++A PD+ + L DD +F+V+ACDGI Sbjct: 384 VTMDGRVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPDIKVLTLTDDHEFMVIACDGI 443 Query: 499 WDCMSSQQLVDFIHEHLKTESS------LSAVCEKVLDRCLAPSTLG-GEGCDNMTMILV 657 W+ MSSQ++VDFI + LS++ E++LD+CLAP T G G GCDNMT I++ Sbjct: 444 WNVMSSQEVVDFIQSKISQRDENGELRLLSSIVEELLDQCLAPDTSGDGTGCDNMTCIII 503 Query: 658 QFK 666 FK Sbjct: 504 CFK 506
>PP2CG_MOUSE (Q61074) Protein phosphatase 2C isoform gamma (EC 3.1.3.16)| (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C) (Fibroblast growth factor-inducible protein 13) (FIN13) Length = 542 Score = 193 bits (491), Expect = 4e-49 Identities = 99/183 (54%), Positives = 130/183 (71%), Gaps = 8/183 (4%) Frame = +1 Query: 142 GPTCGSTACVAMVRNSQLVVANAGDSRCVISRNGQAYNLSRDHKPELEAERERILKAGGY 321 G G+TA VA++R QL+VANAGDSRCV+S G+A ++S DHKPE E E RI AGG Sbjct: 321 GSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGK 380 Query: 322 IQM-GRVNGTINLSRAIGDMEFKQNKFLSPDKQMLTANPDVNTVELCDDDDFLVLACDGI 498 + M GRVNG +NLSRAIGD +K+NK L P +QM++A PD+ + L DD +F+V+ACDGI Sbjct: 381 VTMDGRVNGGLNLSRAIGDHFYKRNKNLPPQEQMISALPDIKVLTLTDDHEFMVIACDGI 440 Query: 499 WDCMSSQQLVDFIHEHLKTESS------LSAVCEKVLDRCLAPSTLG-GEGCDNMTMILV 657 W+ MSSQ++VDFI + LS++ E++LD+CLAP T G G GCDNMT I++ Sbjct: 441 WNVMSSQEVVDFIQSKISQRDENGELRLLSSIVEELLDQCLAPDTSGDGTGCDNMTCIII 500 Query: 658 QFK 666 FK Sbjct: 501 CFK 503
>PP2CG_BOVIN (P79126) Protein phosphatase 2C isoform gamma (EC 3.1.3.16)| (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1B) (Magnesium-dependent calcium inhibitable phosphatase) (MCPP) Length = 543 Score = 192 bits (489), Expect = 6e-49 Identities = 98/183 (53%), Positives = 130/183 (71%), Gaps = 8/183 (4%) Frame = +1 Query: 142 GPTCGSTACVAMVRNSQLVVANAGDSRCVISRNGQAYNLSRDHKPELEAERERILKAGGY 321 G G+TA VA++R QL+VANAGDSRCV+S G+A ++S DHKPE E E RI AGG Sbjct: 322 GSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGK 381 Query: 322 IQM-GRVNGTINLSRAIGDMEFKQNKFLSPDKQMLTANPDVNTVELCDDDDFLVLACDGI 498 + M GRVNG +NLSRAIGD +K+NK L P++QM++A PD+ + L DD +F+V+ACDGI Sbjct: 382 VTMDGRVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPDIKVLTLTDDHEFMVIACDGI 441 Query: 499 WDCMSSQQLVDFIHEHLKTESS------LSAVCEKVLDRCLAPSTLG-GEGCDNMTMILV 657 W+ MSSQ+++DFI + LS++ E +LD+CLAP T G G GCDNMT I++ Sbjct: 442 WNVMSSQEVIDFIQSKISQRDENGELRLLSSIVEYLLDQCLAPDTSGDGTGCDNMTCIII 501 Query: 658 QFK 666 FK Sbjct: 502 CFK 504
>PP2C1_CAEEL (P49595) Probable protein phosphatase 2C F42G9.1 (EC 3.1.3.16)| (PP2C) Length = 491 Score = 186 bits (472), Expect = 6e-47 Identities = 95/181 (52%), Positives = 125/181 (69%), Gaps = 1/181 (0%) Frame = +1 Query: 130 SDFSGPTCGSTACVAMVRNSQLVVANAGDSRCVISRNGQAYNLSRDHKPELEAERERILK 309 ++ G G+TACV +V +++VANAGDSR V+ RNG+A +LS DHKPE E E RI Sbjct: 308 AEVPGEDSGTTACVCLVGKDKVIVANAGDSRAVLCRNGKAVDLSVDHKPEDEVETNRIHA 367 Query: 310 AGGYIQMGRVNGTINLSRAIGDMEFKQNKFLSPDKQMLTANPDVNTVELCDDDDFLVLAC 489 AGG I+ GRVNG +NLSRA GD +K+N+ L +QM+TA PDV L +D+F+V+AC Sbjct: 368 AGGQIEDGRVNGGLNLSRAFGDHAYKKNQELGLKEQMITALPDVKIEALTPEDEFIVVAC 427 Query: 490 DGIWDCMSSQQLVDFIHEHLKTESSLSAVCEKVLDRCLAPSTLG-GEGCDNMTMILVQFK 666 DGIW+ M SQQ+VDF+ + L SS + VC+ + D CLA ST G G GCDNMT+I F Sbjct: 428 DGIWNSMESQQVVDFVRDLLAKGSSCAEVCDALCDACLADSTDGDGTGCDNMTVICTTFD 487 Query: 667 K 669 + Sbjct: 488 R 488
>PP2C2_SCHPO (Q09172) Protein phosphatase 2C homolog 2 (EC 3.1.3.16) (PP2C-2)| Length = 370 Score = 178 bits (452), Expect = 1e-44 Identities = 89/179 (49%), Positives = 121/179 (67%), Gaps = 2/179 (1%) Frame = +1 Query: 133 DFSGPTCGSTACVAMVRNSQLVV-ANAGDSRCVISRNGQAYNLSRDHKPELEAERERILK 309 D G TA A++ + Q++ ANAGDSR V+ R G A LS DHKP + E+ RI Sbjct: 113 DMQEDPSGCTATTALIVDHQVIYCANAGDSRTVLGRKGTAEPLSFDHKPNNDVEKARITA 172 Query: 310 AGGYIQMGRVNGTINLSRAIGDMEFKQNKFLSPDKQMLTANPDVNTVELCDDDDFLVLAC 489 AGG+I GRVNG++ LSRAIGD E+K++ L P+KQ++TA PDV + DD+FL+LAC Sbjct: 173 AGGFIDFGRVNGSLALSRAIGDFEYKKDSSLPPEKQIVTAFPDVVIHNIDPDDEFLILAC 232 Query: 490 DGIWDCMSSQQLVDFIHEHLKTESSLSAVCEKVLDRCLAPSTLG-GEGCDNMTMILVQF 663 DGIWDC SSQQ+V+F+ + SL +CE ++DRC+A ++ G GCDNMT+ +V F Sbjct: 233 DGIWDCKSSQQVVEFVRRGIVARQSLEVICENLMDRCIASNSESCGIGCDNMTICIVAF 291
>PP2C3_SCHPO (Q09173) Protein phosphatase 2C homolog 3 (EC 3.1.3.16) (PP2C-3)| Length = 414 Score = 173 bits (438), Expect = 5e-43 Identities = 88/169 (52%), Positives = 115/169 (68%), Gaps = 1/169 (0%) Frame = +1 Query: 154 GSTACVAMVRNSQLVVANAGDSRCVISRNGQAYNLSRDHKPELEAERERILKAGGYIQMG 333 G TA V + ++L ANAGDSR V+ G A LS DHKP EAE+ RI AGG++ G Sbjct: 119 GCTATVVLRVGNKLYCANAGDSRTVLGSKGIAKPLSADHKPSNEAEKARICAAGGFVDFG 178 Query: 334 RVNGTINLSRAIGDMEFKQNKFLSPDKQMLTANPDVNTVELCDDDDFLVLACDGIWDCMS 513 RVNG + LSRAIGD EFK N L P+KQ++TA PDV E+ DDD+F+VLACDGIWDC + Sbjct: 179 RVNGNLALSRAIGDFEFK-NSNLEPEKQIVTALPDVVVHEITDDDEFVVLACDGIWDCKT 237 Query: 514 SQQLVDFIHEHLKTESSLSAVCEKVLDRCLAPST-LGGEGCDNMTMILV 657 SQQ+++F+ + +SL + E ++D C+A T G GCDNMT+ +V Sbjct: 238 SQQVIEFVRRGIVAGTSLEKIAENLMDNCIASDTETTGLGCDNMTVCIV 286
>PP2C2_CAEEL (P49596) Probable protein phosphatase 2C T23F11.1 (EC 3.1.3.16)| (PP2C) Length = 356 Score = 168 bits (425), Expect = 2e-41 Identities = 83/169 (49%), Positives = 115/169 (68%), Gaps = 1/169 (0%) Frame = +1 Query: 154 GSTACVAMVRNSQLVVANAGDSRCVISRNGQAYNLSRDHKPELEAERERILKAGGYIQMG 333 G+TA V +++ + NAGDSR V S G+A LS DHKP E E RI+ AGG+++ Sbjct: 116 GTTAVVVLIKEGDVYCGNAGDSRAVSSVVGEARPLSFDHKPSHETEARRIIAAGGWVEFN 175 Query: 334 RVNGTINLSRAIGDMEFKQNKFLSPDKQMLTANPDVNTVELCDDDDFLVLACDGIWDCMS 513 RVNG + LSRA+GD FK ++Q++TA PDV T +L D +F+VLACDGIWD M+ Sbjct: 176 RVNGNLALSRALGDFAFKNCDTKPAEEQIVTAFPDVITDKLTPDHEFIVLACDGIWDVMT 235 Query: 514 SQQLVDFIHEHLKTESSLSAVCEKVLDRCLAPS-TLGGEGCDNMTMILV 657 +Q++VDF+ E L + ++CE++L RCLAP +GG GCDNMT++LV Sbjct: 236 NQEVVDFVREKLAEKRDPQSICEELLTRCLAPDCQMGGLGCDNMTVVLV 284
>PP2C2_YEAST (P39966) Protein phosphatase 2C homolog 2 (EC 3.1.3.16) (PP2C-2)| Length = 464 Score = 165 bits (418), Expect = 1e-40 Identities = 85/176 (48%), Positives = 119/176 (67%), Gaps = 4/176 (2%) Frame = +1 Query: 154 GSTACVAMVRNSQ--LVVANAGDSRCVISRNGQAYNLSRDHKPELEAERERILKAGGYIQ 327 G TA +V SQ LV NAGDSR V++ +G A LS DHKP L +E+ RI+ A G+++ Sbjct: 119 GCTATSILVSKSQNLLVCGNAGDSRTVLATDGNAKALSYDHKPTLASEKSRIVAADGFVE 178 Query: 328 MGRVNGTINLSRAIGDMEFKQNKFLSPDKQMLTANPDVNTVEL-CDDDDFLVLACDGIWD 504 M RVNG + LSRAIGD EFK N L P++Q++T PD+ L D D+F++LACDGIWD Sbjct: 179 MDRVNGNLALSRAIGDFEFKSNPKLGPEEQIVTCVPDILEHSLDYDRDEFVILACDGIWD 238 Query: 505 CMSSQQLVDFIHEHLKTESSLSAVCEKVLDRCLAPSTLG-GEGCDNMTMILVQFKK 669 C++SQ VD +H L+ +L+ + +++D C AP+T G G GCDNM++++V K Sbjct: 239 CLTSQDCVDLVHLGLREGKTLNEISSRIIDVCCAPTTEGTGIGCDNMSIVVVALLK 294
>PP2C3_YEAST (P34221) Protein phosphatase 2C homolog 3 (EC 3.1.3.16) (PP2C-3)| Length = 468 Score = 155 bits (393), Expect = 8e-38 Identities = 82/188 (43%), Positives = 121/188 (64%), Gaps = 3/188 (1%) Frame = +1 Query: 115 EEGPHSDFSGPTCGSTACVAMVRNSQLVVANAGDSRCVISRNGQAYNLSRDHKPELEAER 294 +E D SG C +T + L+ AN+GDSR V+S G + +S DHKP L +E+ Sbjct: 110 DEKLKDDHSG--CTATVILVSQLKKLLICANSGDSRTVLSTGGNSKAMSFDHKPTLLSEK 167 Query: 295 ERILKAGGYIQMGRVNGTINLSRAIGDMEFKQNKFLSPDKQMLTANPDVNTVEL-CDDDD 471 RI+ A G+++M RVNG + LSRAIGD EFK N L P +Q++T PD+ L D+D+ Sbjct: 168 SRIVAADGFVEMDRVNGNLALSRAIGDFEFKSNTKLGPHEQVVTCVPDIICHNLNYDEDE 227 Query: 472 FLVLACDGIWDCMSSQQLVDFIHEHL-KTESSLSAVCEKVLDRCLAPSTLG-GEGCDNMT 645 F++LACDGIWDC++SQ+ VD +H + + +LS + +++D C +P+T G G GCDNM+ Sbjct: 228 FVILACDGIWDCLTSQECVDLVHYGISQGNMTLSDISSRIVDVCCSPTTEGSGIGCDNMS 287 Query: 646 MILVQFKK 669 + +V K Sbjct: 288 ISIVALLK 295
>PP2C_PARTE (P49444) Protein phosphatase 2C (EC 3.1.3.16) (PP2C)| Length = 300 Score = 155 bits (392), Expect = 1e-37 Identities = 77/176 (43%), Positives = 116/176 (65%), Gaps = 4/176 (2%) Frame = +1 Query: 154 GSTACVAMVRNSQLVVANAGDSRCVISRNGQAYNLSRDHKPELEAERERILKAGGYIQMG 333 G TA VA++ + L VANAGDSR V+ RN +++S DHKP+ E+ RI +AGG++ G Sbjct: 125 GCTANVALIYKNTLYVANAGDSRSVLCRNNTNHDMSVDHKPDNPEEKSRIERAGGFVSDG 184 Query: 334 RVNGTINLSRAIGDMEFKQNKFLSPDKQMLTANPDVNTVELCDDDDFLVLACDGIWDCMS 513 RVNG +NLSRA+GD+E+K++ L ++Q++ A PDV EL D F+++ CDG+++ ++ Sbjct: 185 RVNGNLNLSRALGDLEYKRDNKLRSNEQLIIALPDVKKTELTPQDKFILMGCDGVFETLN 244 Query: 514 SQQLVDFIHEHL----KTESSLSAVCEKVLDRCLAPSTLGGEGCDNMTMILVQFKK 669 Q+L+ ++ + TE L E +LD+ LAP T G GCDNMT ILV ++ Sbjct: 245 HQELLKQVNSTIGQAQVTEELLKKAAEDLLDQLLAPDTSQGTGCDNMTTILVYLRR 300
>PP2CB_MOUSE (P36993) Protein phosphatase 2C isoform beta (EC 3.1.3.16)| (PP2C-beta) (IA) (Protein phosphatase 1B) Length = 390 Score = 137 bits (346), Expect = 2e-32 Identities = 70/170 (41%), Positives = 105/170 (61%) Frame = +1 Query: 154 GSTACVAMVRNSQLVVANAGDSRCVISRNGQAYNLSRDHKPELEAERERILKAGGYIQMG 333 GSTA MV + + N GDSR V+ RNGQ ++DHKP E+ERI AGG + + Sbjct: 131 GSTAVGVMVSPTHMYFINCGDSRAVLCRNGQVCFSTQDHKPCNPVEKERIQNAGGSVMIQ 190 Query: 334 RVNGTINLSRAIGDMEFKQNKFLSPDKQMLTANPDVNTVELCDDDDFLVLACDGIWDCMS 513 RVNG++ +SRA+GD ++K P +Q+++ P+V + ++D+F+VLACDGIWD MS Sbjct: 191 RVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEIVRAEEDEFVVLACDGIWDVMS 250 Query: 514 SQQLVDFIHEHLKTESSLSAVCEKVLDRCLAPSTLGGEGCDNMTMILVQF 663 +++L +F+ L+ L VC V+D CL + DNM+++LV F Sbjct: 251 NEELCEFVKSRLEVSDDLENVCNWVVDTCLHKGSR-----DNMSVVLVCF 295
>PP2CB_RAT (P35815) Protein phosphatase 2C isoform beta (EC 3.1.3.16)| (PP2C-beta) (IA) (Protein phosphatase 1B) Length = 390 Score = 137 bits (345), Expect = 3e-32 Identities = 69/170 (40%), Positives = 106/170 (62%) Frame = +1 Query: 154 GSTACVAMVRNSQLVVANAGDSRCVISRNGQAYNLSRDHKPELEAERERILKAGGYIQMG 333 GSTA M+ + + N GDSR V+ RNGQ ++DHKP E+ERI AGG + + Sbjct: 131 GSTAVGVMISPTHIYFINCGDSRAVLCRNGQVCFSTQDHKPCNPMEKERIQNAGGSVMIQ 190 Query: 334 RVNGTINLSRAIGDMEFKQNKFLSPDKQMLTANPDVNTVELCDDDDFLVLACDGIWDCMS 513 RVNG++ +SRA+GD ++K P +Q+++ P+V + ++D+F+VLACDGIWD MS Sbjct: 191 RVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFVVLACDGIWDVMS 250 Query: 514 SQQLVDFIHEHLKTESSLSAVCEKVLDRCLAPSTLGGEGCDNMTMILVQF 663 +++L +F++ L+ L VC V+D CL + DNM+++LV F Sbjct: 251 NEELCEFVNSRLEVSDDLENVCNWVVDTCLHKGSR-----DNMSIVLVCF 295
>PP2CA_BOVIN (O62829) Protein phosphatase 2C isoform alpha (EC 3.1.3.16)| (PP2C-alpha) Length = 382 Score = 135 bits (341), Expect = 9e-32 Identities = 67/171 (39%), Positives = 105/171 (61%), Gaps = 1/171 (0%) Frame = +1 Query: 154 GSTACVAMVRNSQLVVANAGDSRCVISRNGQAYNLSRDHKPELEAERERILKAGGYIQMG 333 GSTA ++ N GDSR ++ RN + Y ++DHKP E+ERI AGG + + Sbjct: 126 GSTAVGVLISPQHTYFINCGDSRGLLCRNRKVYFFTQDHKPSNPLEKERIQNAGGSVMIQ 185 Query: 334 RVNGTINLSRAIGDMEFKQNKFLSPDKQMLTANPDVNTVELCDDDD-FLVLACDGIWDCM 510 RVNG++ +SRA+GD ++K P +Q+++ P+V+ +E ++DD F++LACDGIWD M Sbjct: 186 RVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVM 245 Query: 511 SSQQLVDFIHEHLKTESSLSAVCEKVLDRCLAPSTLGGEGCDNMTMILVQF 663 +++L DF+ L+ L VC +V+D CL + DNM++IL+ F Sbjct: 246 GNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSR-----DNMSVILICF 291
>PP2CB_HUMAN (O75688) Protein phosphatase 2C isoform beta (EC 3.1.3.16)| (PP2C-beta) Length = 479 Score = 134 bits (338), Expect = 2e-31 Identities = 67/170 (39%), Positives = 104/170 (61%) Frame = +1 Query: 154 GSTACVAMVRNSQLVVANAGDSRCVISRNGQAYNLSRDHKPELEAERERILKAGGYIQMG 333 GSTA M+ + N GDSR V+ RNGQ ++DHKP E+ERI AGG + + Sbjct: 131 GSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGGSVMIQ 190 Query: 334 RVNGTINLSRAIGDMEFKQNKFLSPDKQMLTANPDVNTVELCDDDDFLVLACDGIWDCMS 513 RVNG++ +SRA+GD ++K P +Q+++ P+V + ++D+F++LACDGIWD MS Sbjct: 191 RVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIILACDGIWDVMS 250 Query: 514 SQQLVDFIHEHLKTESSLSAVCEKVLDRCLAPSTLGGEGCDNMTMILVQF 663 +++L +++ L+ L VC V+D CL + DNM+++LV F Sbjct: 251 NEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSR-----DNMSIVLVCF 295
>PP2CA_RAT (P20650) Protein phosphatase 2C isoform alpha (EC 3.1.3.16)| (PP2C-alpha) (IA) (Protein phosphatase 1A) Length = 382 Score = 134 bits (336), Expect = 3e-31 Identities = 66/171 (38%), Positives = 105/171 (61%), Gaps = 1/171 (0%) Frame = +1 Query: 154 GSTACVAMVRNSQLVVANAGDSRCVISRNGQAYNLSRDHKPELEAERERILKAGGYIQMG 333 GSTA ++ N GDSR ++ RN + + ++DHKP E+ERI AGG + + Sbjct: 126 GSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGGSVMIQ 185 Query: 334 RVNGTINLSRAIGDMEFKQNKFLSPDKQMLTANPDVNTVELCDDDD-FLVLACDGIWDCM 510 RVNG++ +SRA+GD ++K P +Q+++ P+V+ +E ++DD F++LACDGIWD M Sbjct: 186 RVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVM 245 Query: 511 SSQQLVDFIHEHLKTESSLSAVCEKVLDRCLAPSTLGGEGCDNMTMILVQF 663 +++L DF+ L+ L VC +V+D CL + DNM++IL+ F Sbjct: 246 GNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSR-----DNMSVILICF 291
>PP2CA_RABIT (P35814) Protein phosphatase 2C isoform alpha (EC 3.1.3.16)| (PP2C-alpha) (IA) (Protein phosphatase 1A) Length = 382 Score = 134 bits (336), Expect = 3e-31 Identities = 66/171 (38%), Positives = 105/171 (61%), Gaps = 1/171 (0%) Frame = +1 Query: 154 GSTACVAMVRNSQLVVANAGDSRCVISRNGQAYNLSRDHKPELEAERERILKAGGYIQMG 333 GSTA ++ N GDSR ++ RN + + ++DHKP E+ERI AGG + + Sbjct: 126 GSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGGSVMIQ 185 Query: 334 RVNGTINLSRAIGDMEFKQNKFLSPDKQMLTANPDVNTVELCDDDD-FLVLACDGIWDCM 510 RVNG++ +SRA+GD ++K P +Q+++ P+V+ +E ++DD F++LACDGIWD M Sbjct: 186 RVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVM 245 Query: 511 SSQQLVDFIHEHLKTESSLSAVCEKVLDRCLAPSTLGGEGCDNMTMILVQF 663 +++L DF+ L+ L VC +V+D CL + DNM++IL+ F Sbjct: 246 GNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSR-----DNMSVILICF 291
>PP2CA_MOUSE (P49443) Protein phosphatase 2C isoform alpha (EC 3.1.3.16)| (PP2C-alpha) (IA) (Protein phosphatase 1A) Length = 382 Score = 134 bits (336), Expect = 3e-31 Identities = 66/171 (38%), Positives = 105/171 (61%), Gaps = 1/171 (0%) Frame = +1 Query: 154 GSTACVAMVRNSQLVVANAGDSRCVISRNGQAYNLSRDHKPELEAERERILKAGGYIQMG 333 GSTA ++ N GDSR ++ RN + + ++DHKP E+ERI AGG + + Sbjct: 126 GSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGGSVMIQ 185 Query: 334 RVNGTINLSRAIGDMEFKQNKFLSPDKQMLTANPDVNTVELCDDDD-FLVLACDGIWDCM 510 RVNG++ +SRA+GD ++K P +Q+++ P+V+ +E ++DD F++LACDGIWD M Sbjct: 186 RVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVM 245 Query: 511 SSQQLVDFIHEHLKTESSLSAVCEKVLDRCLAPSTLGGEGCDNMTMILVQF 663 +++L DF+ L+ L VC +V+D CL + DNM++IL+ F Sbjct: 246 GNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSR-----DNMSVILICF 291
>PP2CA_HUMAN (P35813) Protein phosphatase 2C isoform alpha (EC 3.1.3.16)| (PP2C-alpha) (IA) (Protein phosphatase 1A) Length = 382 Score = 134 bits (336), Expect = 3e-31 Identities = 66/171 (38%), Positives = 105/171 (61%), Gaps = 1/171 (0%) Frame = +1 Query: 154 GSTACVAMVRNSQLVVANAGDSRCVISRNGQAYNLSRDHKPELEAERERILKAGGYIQMG 333 GSTA ++ N GDSR ++ RN + + ++DHKP E+ERI AGG + + Sbjct: 126 GSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGGSVMIQ 185 Query: 334 RVNGTINLSRAIGDMEFKQNKFLSPDKQMLTANPDVNTVELCDDDD-FLVLACDGIWDCM 510 RVNG++ +SRA+GD ++K P +Q+++ P+V+ +E ++DD F++LACDGIWD M Sbjct: 186 RVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVM 245 Query: 511 SSQQLVDFIHEHLKTESSLSAVCEKVLDRCLAPSTLGGEGCDNMTMILVQF 663 +++L DF+ L+ L VC +V+D CL + DNM++IL+ F Sbjct: 246 GNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSR-----DNMSVILICF 291
>PP2CB_BOVIN (O62830) Protein phosphatase 2C isoform beta (EC 3.1.3.16)| (PP2C-beta) Length = 387 Score = 134 bits (336), Expect = 3e-31 Identities = 67/170 (39%), Positives = 104/170 (61%) Frame = +1 Query: 154 GSTACVAMVRNSQLVVANAGDSRCVISRNGQAYNLSRDHKPELEAERERILKAGGYIQMG 333 GSTA M+ + N GDSR V+ R+GQ ++DHKP E+ERI AGG + + Sbjct: 131 GSTAVGVMISPKHIYFINCGDSRAVLYRSGQVCFSTQDHKPCNPREKERIQNAGGSVMIQ 190 Query: 334 RVNGTINLSRAIGDMEFKQNKFLSPDKQMLTANPDVNTVELCDDDDFLVLACDGIWDCMS 513 RVNG++ +SRA+GD ++K P +Q+++ P+V + ++D+F++LACDGIWD MS Sbjct: 191 RVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIILACDGIWDVMS 250 Query: 514 SQQLVDFIHEHLKTESSLSAVCEKVLDRCLAPSTLGGEGCDNMTMILVQF 663 +++L +F+ L+ L VC V+D CL + DNM+++LV F Sbjct: 251 NEELCEFVKSRLEVSDDLENVCNWVVDTCLHKGSR-----DNMSIVLVCF 295
>PP2C4_YEAST (P38089) Protein phosphatase 2C homolog 4 (EC 3.1.3.16) (PP2C-4)| Length = 393 Score = 123 bits (308), Expect = 6e-28 Identities = 77/203 (37%), Positives = 108/203 (53%), Gaps = 22/203 (10%) Frame = +1 Query: 115 EEGPHSDFSGPTCGSTACVAMVRNSQ-LVVANAGDSRCVISRNGQAYN-LSRDHKPELEA 288 +E + F+ +CGSTA VA + N + L VAN GDSRC++S +S DHKP+ Sbjct: 164 DEELYRHFANSSCGSTAVVACIINEESLYVANCGDSRCILSSKSNGIKTMSFDHKPQHIG 223 Query: 289 ERERILKAGGYIQMGRVNGTINLSRAIGDMEFKQNKFLS------------------PDK 414 E RI GG + +GRV G + LSRA D +FK+ P + Sbjct: 224 ELIRINDNGGTVSLGRVGGVLALSRAFSDFQFKRGVTYPHRRTKLTNITQNLTYGTPPQE 283 Query: 415 QMLTANPDVNTVEL-CDDDDFLVLACDGIWDCMSSQQLVDFIHEHLKTESSLSAVCEKVL 591 +T PDV ++ D+FLVLACDGIWD +++QL+ FI HL + + L + K+L Sbjct: 284 AQVTVEPDVLMHKIDYSKDEFLVLACDGIWDIYNNKQLIHFIKYHLVSGTKLDTIITKLL 343 Query: 592 DRCLAPSTLG-GEGCDNMTMILV 657 D +A + G G DNMT I+V Sbjct: 344 DHGIAQANSNTGVGFDNMTAIIV 366
>PP2C3_ARATH (P49599) Protein phosphatase 2C PPH1 (EC 3.1.3.16) (PP2C)| Length = 388 Score = 106 bits (265), Expect = 6e-23 Identities = 82/245 (33%), Positives = 122/245 (49%), Gaps = 27/245 (11%) Frame = +1 Query: 1 GELQALGDKIN--QFTGMIEGLIWSPRGSDSNDRHD-DWAFEEGPHSDFSGPTCGSTACV 171 G LQA G +N F + E LI + +S DR+ W G D SG STA V Sbjct: 114 GALQA-GSLLNGGDFAAIKEALI---KAFESVDRNLLKWLEANGDEEDESG----STATV 165 Query: 172 AMVRNSQLVVANAGDSRCVISRNGQAYNLSRDHKPELEA-----ERERILKAGGYIQMGR 336 ++RN +A+ GDS V+SR+GQ L+ H+P + E +R+ +AGG+I GR Sbjct: 166 MIIRNDVSFIAHIGDSCAVLSRSGQIEELTDYHRPYGSSRAAIQEVKRVKEAGGWIVNGR 225 Query: 337 VNGTINLSRAIGDMEFK----------------QNKFLSPDK---QMLTANPDVNTVELC 459 + G I +SRA GD+ FK KF+S + M+ A PD+ V L Sbjct: 226 ICGDIAVSRAFGDIRFKTKKNDMLKKGVDEGRWSEKFVSRIEFKGDMVVATPDIFQVPLT 285 Query: 460 DDDDFLVLACDGIWDCMSSQQLVDFIHEHLKTESSLSAVCEKVLDRCLAPSTLGGEGCDN 639 D +F++LA DG+WD M S +V ++ + L+ ++ CE LA L DN Sbjct: 286 SDVEFIILASDGLWDYMKSSDVVSYVRDQLRKHGNVQLACES-----LAQVALDRRSQDN 340 Query: 640 MTMIL 654 +++I+ Sbjct: 341 ISIII 345
>PP2C1_SCHPO (P40371) Protein phosphatase 2C homolog 1 (EC 3.1.3.16) (PP2C-1)| Length = 347 Score = 97.4 bits (241), Expect = 3e-20 Identities = 58/180 (32%), Positives = 91/180 (50%), Gaps = 7/180 (3%) Frame = +1 Query: 151 CGSTACVAMVRNSQ------LVVANAGDSRCVISRNGQAYNLSRDHKPELEAERERILKA 312 CG TA VA R + L ANAGD+R V+ R+G+A LS DHK E R+ + Sbjct: 164 CGCTAAVAFFRYEKNRTRRVLYTANAGDARIVLCRDGKAIRLSYDHKGSDANESRRVTQL 223 Query: 313 GGYIQMGRVNGTINLSRAIGDMEFKQNKFLSPDKQMLTANPDVNTVELCD-DDDFLVLAC 489 GG + R+NG + ++RA+GD K++++A+P + + D+F ++AC Sbjct: 224 GGLMVQNRINGVLAVTRALGDTYL---------KELVSAHPFTTETRIWNGHDEFFIIAC 274 Query: 490 DGIWDCMSSQQLVDFIHEHLKTESSLSAVCEKVLDRCLAPSTLGGEGCDNMTMILVQFKK 669 DG+WD +S Q+ VDF+ + + + E L R DN+T I+V + Sbjct: 275 DGLWDVVSDQEAVDFVRNFVSPREAAVRLVEFALKRL---------STDNITCIVVNLTR 325
>PP2CL_MOUSE (Q8BHN0) Protein phosphatase 2C isoform epsilon (EC 3.1.3.16)| (PP2C-epsilon) (Protein phosphatase 1L) (Protein phosphatase 1-like) Length = 360 Score = 96.7 bits (239), Expect = 6e-20 Identities = 63/177 (35%), Positives = 95/177 (53%), Gaps = 6/177 (3%) Frame = +1 Query: 154 GSTACVAMVRNSQLVVANAGDSRCVI-SRNGQAYNLSRDHKPELEAERERILKAGGYIQM 330 G+T +A++ + L VAN GDSR V+ ++G A LS DHKP ER+RI +AGG+I Sbjct: 192 GTTCLIALLSDKDLTVANVGDSRGVLCDKDGNAIPLSHDHKPYQLKERKRIKRAGGFISF 251 Query: 331 G---RVNGTINLSRAIGDMEFKQNKFLSPDKQMLTANPDVNTVELCDDDDFLVLACDGIW 501 RV G + +SR++GD K + PD +LT + D E F++LA DG+W Sbjct: 252 NGSWRVQGILAMSRSLGDYPLKNLNVVIPDPDILTFDLDKLQPE------FMILASDGLW 305 Query: 502 DCMSSQQLVDFIHEHLKTE--SSLSAVCEKVLDRCLAPSTLGGEGCDNMTMILVQFK 666 D S+++ V FI E L + S V + C DN+T+++V+F+ Sbjct: 306 DAFSNEEAVRFIKERLDEPHFGAKSIVLQSFYRGC----------PDNITVMVVKFR 352
>PP2CL_HUMAN (Q5SGD2) Protein phosphatase 2C isoform epsilon (EC 3.1.3.16)| (PP2C-epsilon) (Protein phosphatase 1L) (Protein phosphatase 1-like) Length = 360 Score = 96.7 bits (239), Expect = 6e-20 Identities = 63/177 (35%), Positives = 95/177 (53%), Gaps = 6/177 (3%) Frame = +1 Query: 154 GSTACVAMVRNSQLVVANAGDSRCVI-SRNGQAYNLSRDHKPELEAERERILKAGGYIQM 330 G+T +A++ + L VAN GDSR V+ ++G A LS DHKP ER+RI +AGG+I Sbjct: 192 GTTCLIALLSDKDLTVANVGDSRGVLCDKDGNAIPLSHDHKPYQLKERKRIKRAGGFISF 251 Query: 331 G---RVNGTINLSRAIGDMEFKQNKFLSPDKQMLTANPDVNTVELCDDDDFLVLACDGIW 501 RV G + +SR++GD K + PD +LT + D E F++LA DG+W Sbjct: 252 NGSWRVQGILAMSRSLGDYPLKNLNVVIPDPDILTFDLDKLQPE------FMILASDGLW 305 Query: 502 DCMSSQQLVDFIHEHLKTE--SSLSAVCEKVLDRCLAPSTLGGEGCDNMTMILVQFK 666 D S+++ V FI E L + S V + C DN+T+++V+F+ Sbjct: 306 DAFSNEEAVRFIKERLDEPHFGAKSIVLQSFYRGC----------PDNITVMVVKFR 352
>PP2C4_ARATH (P49598) Protein phosphatase 2C (EC 3.1.3.16) (PP2C)| Length = 399 Score = 94.4 bits (233), Expect = 3e-19 Identities = 64/192 (33%), Positives = 101/192 (52%), Gaps = 13/192 (6%) Frame = +1 Query: 133 DFSGPTC---GSTACVAMVRNSQLVVANAGDSRCVISRNGQAYNLSRDHKPELEAERERI 303 + P C GSTA V++V +++V+N GDSR V+ RNG A LS DHKP+ E RI Sbjct: 211 ELQSPQCDAVGSTAVVSVVTPEKIIVSNCGDSRAVLCRNGVAIPLSVDHKPDRPDELIRI 270 Query: 304 LKAGG---YIQMGRVNGTINLSRAIGDMEFKQNKFLSPDKQMLTANPDVNTVELCDDDDF 474 +AGG Y RV G + +SRAIGD K ++ PD P+V + D+D+ Sbjct: 271 QQAGGRVIYWDGARVLGVLAMSRAIGDNYLK--PYVIPD-------PEVTVTDRTDEDEC 321 Query: 475 LVLACDGIWDCMSSQQLVDFIHEHLK-------TESSLSAVCEKVLDRCLAPSTLGGEGC 633 L+LA DG+WD + ++ L+ ++++ +A + L L L + Sbjct: 322 LILASDGLWDVVPNETACGVARMCLRGAGAGDDSDAAHNACSDAAL--LLTKLALARQSS 379 Query: 634 DNMTMILVQFKK 669 DN+++++V +K Sbjct: 380 DNVSVVVVDLRK 391
>PP2C2_ARATH (O04719) Protein phosphatase 2C ABI2 (EC 3.1.3.16) (PP2C) (Abscisic| acid-insensitive 2) Length = 423 Score = 93.6 bits (231), Expect = 5e-19 Identities = 60/175 (34%), Positives = 92/175 (52%), Gaps = 3/175 (1%) Frame = +1 Query: 148 TCGSTACVAMVRNSQLVVANAGDSRCVISRNGQAYNLSRDHKPELEAERERILKAGGYI- 324 T GST+ VA+V + + VAN GDSR V+ R LS DHKP+ + E RI AGG + Sbjct: 229 TVGSTSVVAVVFPTHIFVANCGDSRAVLCRGKTPLALSVDHKPDRDDEAARIEAAGGKVI 288 Query: 325 --QMGRVNGTINLSRAIGDMEFKQNKFLSPDKQMLTANPDVNTVELCDDDDFLVLACDGI 498 RV G + +SR+IGD ++L P + +P+V +V +DD L+LA DG+ Sbjct: 289 RWNGARVFGVLAMSRSIGD------RYLKPS---VIPDPEVTSVRRVKEDDCLILASDGL 339 Query: 499 WDCMSSQQLVDFIHEHLKTESSLSAVCEKVLDRCLAPSTLGGEGCDNMTMILVQF 663 WD M+++++ D + + +A+ L P+ GEG D M ++ Sbjct: 340 WDVMTNEEVCDLARKRILLWHKKNAMA----GEALLPAEKRGEGKDPAAMSAAEY 390
>PP2C1_ARATH (P49597) Protein phosphatase 2C ABI1 (EC 3.1.3.16) (PP2C) (Abscisic| acid-insensitive 1) Length = 434 Score = 92.0 bits (227), Expect = 1e-18 Identities = 62/175 (35%), Positives = 89/175 (50%), Gaps = 3/175 (1%) Frame = +1 Query: 148 TCGSTACVAMVRNSQLVVANAGDSRCVISRNGQAYNLSRDHKPELEAERERILKAGGYI- 324 T GST+ VA+V S + VAN GDSR V+ R A LS DHKP+ E E RI AGG + Sbjct: 239 TVGSTSVVAVVFPSHIFVANCGDSRAVLCRGKTALPLSVDHKPDREDEAARIEAAGGKVI 298 Query: 325 --QMGRVNGTINLSRAIGDMEFKQNKFLSPDKQMLTANPDVNTVELCDDDDFLVLACDGI 498 RV G + +SR+IGD ++L P + +P+V V+ +DD L+LA DG+ Sbjct: 299 QWNGARVFGVLAMSRSIGD------RYLKPS---IIPDPEVTAVKRVKEDDCLILASDGV 349 Query: 499 WDCMSSQQLVDFIHEHLKTESSLSAVCEKVLDRCLAPSTLGGEGCDNMTMILVQF 663 WD M+ ++ + + + +AV D L EG D M ++ Sbjct: 350 WDVMTDEEACEMARKRILLWHKKNAVAG---DASLLADERRKEGKDPAAMSAAEY 401
>PP2C1_YEAST (P35182) Protein phosphatase 2C homolog 1 (EC 3.1.3.16) (PP2C-1)| Length = 281 Score = 90.1 bits (222), Expect = 6e-18 Identities = 56/156 (35%), Positives = 85/156 (54%) Frame = +1 Query: 190 QLVVANAGDSRCVISRNGQAYNLSRDHKPELEAERERILKAGGYIQMGRVNGTINLSRAI 369 +L AN GDSR V+ RNG + L+ DHK E +R+ +AGG I RVNG + ++R++ Sbjct: 142 KLYTANVGDSRIVLFRNGNSIRLTYDHKASDTLEMQRVEQAGGLIMKSRVNGMLAVTRSL 201 Query: 370 GDMEFKQNKFLSPDKQMLTANPDVNTVELCDDDDFLVLACDGIWDCMSSQQLVDFIHEHL 549 GD F ++ +P +VE+ +D FL+LACDG+WD + Q + I + Sbjct: 202 GDKFF---------DSLVVGSPFTTSVEITSEDKFLILACDGLWDVIDDQDACELIKD-- 250 Query: 550 KTESSLSAVCEKVLDRCLAPSTLGGEGCDNMTMILV 657 TE + +A KVL R L DN+T+++V Sbjct: 251 ITEPNEAA---KVLVR----YALENGTTDNVTVMVV 279
>PP2C_LEICH (P36982) Protein phosphatase 2C (EC 3.1.3.16) (PP2C)| Length = 406 Score = 90.1 bits (222), Expect = 6e-18 Identities = 62/187 (33%), Positives = 103/187 (55%), Gaps = 6/187 (3%) Frame = +1 Query: 139 SGPTCGSTAC--VAMVRNSQ--LVVANAGDSRCVISRNGQAYNLSRDHKPELEAERERIL 306 SG GST VA+ ++ L V N GDSR V +G L+ DHKP E ER+RI Sbjct: 100 SGREGGSTGTFFVALKEGNKVHLQVGNVGDSRVVACIDGVCVPLTEDHKPNNEGERQRIE 159 Query: 307 KAGGYIQMGRVNGTINLSRAIGDMEFKQNKFLSPDKQMLTANPDVNTVELC-DDDDFLVL 483 G ++ RV+G++ +SRA GD E+K S +Q + A DV + D +DF++L Sbjct: 160 NCAGRVENNRVDGSLAVSRAFGDREYKLGSG-SQLEQKVIALADVQHKDFTFDSNDFVLL 218 Query: 484 ACDGIWD-CMSSQQLVDFIHEHLKTESSLSAVCEKVLDRCLAPSTLGGEGCDNMTMILVQ 660 CDG+++ ++++V ++ + L+T + L+ V +V + + + DN++ ++VQ Sbjct: 219 CCDGVFEGNFPNEEVVAYVKQQLETCNDLAEVAGRVCEEAIERGSR-----DNISCMIVQ 273 Query: 661 FKKPIDH 681 FK D+ Sbjct: 274 FKDGSDY 280
>PPM1F_MOUSE (Q8CGA0) Ca(2+)/calmodulin-dependent protein kinase phosphatase (EC| 3.1.3.16) (CaM-kinase phosphatase) (CaMKPase) (Protein phosphatase 1F) Length = 452 Score = 87.8 bits (216), Expect = 3e-17 Identities = 53/178 (29%), Positives = 94/178 (52%), Gaps = 3/178 (1%) Frame = +1 Query: 154 GSTACVAMVRNSQLVVANAGDSRCVISRNGQAYNLSRDHKPELEAERERILKAGGYIQM- 330 G+T A++ + L VA GDS+ ++ + G+ L HKPE + E+ RI GG++ + Sbjct: 251 GTTGVCALIAGAALHVAWLGDSQVILVQQGRVVKLMEPHKPERQDEKARIEALGGFVSLM 310 Query: 331 --GRVNGTINLSRAIGDMEFKQNKFLSPDKQMLTANPDVNTVELCDDDDFLVLACDGIWD 504 RVNGT+ +SRAIGD+ K ++ D + EL +D+L+LACDG +D Sbjct: 311 DCWRVNGTLAVSRAIGDVF---------QKPYVSGEADAASRELTGSEDYLLLACDGFFD 361 Query: 505 CMSSQQLVDFIHEHLKTESSLSAVCEKVLDRCLAPSTLGGEGCDNMTMILVQFKKPID 678 + ++ +H HL ++ + +A + G DN+T+++V ++P++ Sbjct: 362 VVPHHEVTGLVHGHLLRHKGNGM---RIAEELVAVARDRGSH-DNITVMVVFLREPLE 415
>PPM1F_RAT (Q9WVR7) Ca(2+)/calmodulin-dependent protein kinase phosphatase (EC| 3.1.3.16) (CaM-kinase phosphatase) (CaMKPase) (Partner of PIX 2) (Protein phosphatase 1F) Length = 450 Score = 87.4 bits (215), Expect = 4e-17 Identities = 55/178 (30%), Positives = 93/178 (52%), Gaps = 3/178 (1%) Frame = +1 Query: 154 GSTACVAMVRNSQLVVANAGDSRCVISRNGQAYNLSRDHKPELEAERERILKAGGYIQM- 330 G+T A++ + L VA GDS+ ++ + GQ L HKPE + E+ RI GG++ + Sbjct: 250 GTTGVCALITGAALHVAWLGDSQVILVQQGQVVKLMEPHKPERQDEKSRIEALGGFVSLM 309 Query: 331 --GRVNGTINLSRAIGDMEFKQNKFLSPDKQMLTANPDVNTVELCDDDDFLVLACDGIWD 504 RVNGT+ +SRAIGD+ K ++ D + EL +D+L+LACDG +D Sbjct: 310 DCWRVNGTLAVSRAIGDVF---------QKPYVSGEADAASRELTGLEDYLLLACDGFFD 360 Query: 505 CMSSQQLVDFIHEHLKTESSLSAVCEKVLDRCLAPSTLGGEGCDNMTMILVQFKKPID 678 + ++ +H HL + V + +A + G DN+T+++V + P++ Sbjct: 361 VVPHHEIPGLVHGHLLRQKGSGM---HVAEELVAVARDRGSH-DNITVMVVFLRDPLE 414
>PPM1F_HUMAN (P49593) Ca(2+)/calmodulin-dependent protein kinase phosphatase (EC| 3.1.3.16) (CaM-kinase phosphatase) (CaMKPase) (Partner of PIX 2) (hFEM-2) (Protein phosphatase 1F) Length = 454 Score = 86.3 bits (212), Expect = 8e-17 Identities = 54/176 (30%), Positives = 91/176 (51%), Gaps = 3/176 (1%) Frame = +1 Query: 154 GSTACVAMVRNSQLVVANAGDSRCVISRNGQAYNLSRDHKPELEAERERILKAGGYI--- 324 G+T A++ + L VA GDS+ ++ + GQ L H+PE + E+ RI GG++ Sbjct: 254 GTTGVCALIAGATLHVAWLGDSQVILVQQGQVVKLMEPHRPERQDEKARIEALGGFVSHM 313 Query: 325 QMGRVNGTINLSRAIGDMEFKQNKFLSPDKQMLTANPDVNTVELCDDDDFLVLACDGIWD 504 RVNGT+ +SRAIGD+ K ++ D + L +D+L+LACDG +D Sbjct: 314 DCWRVNGTLAVSRAIGDVF---------QKPYVSGEADAASRALTGSEDYLLLACDGFFD 364 Query: 505 CMSSQQLVDFIHEHLKTESSLSAVCEKVLDRCLAPSTLGGEGCDNMTMILVQFKKP 672 + Q++V + HL + +V + +A + G DN+T+++V + P Sbjct: 365 VVPHQEVVGLVQSHLTRQQGSGL---RVAEELVAAARERGSH-DNITVMVVFLRDP 416
>CYAA_YEAST (P08678) Adenylate cyclase (EC 4.6.1.1) (ATP pyrophosphate-lyase)| (Adenylyl cyclase) Length = 2026 Score = 75.5 bits (184), Expect = 1e-13 Identities = 45/162 (27%), Positives = 78/162 (48%), Gaps = 11/162 (6%) Frame = +1 Query: 154 GSTACVAMVRNSQLVVANAGDSRCVISRNGQAYN-LSRDHKPELEAERERILKAGGYIQM 330 G+ + V +R +L AN GD ++S+N Y L++ H P E ERI +GGY+ Sbjct: 1471 GACSTVIYIRGKKLFAANLGDCMAILSKNNGDYQTLTKQHLPTKREEYERIRISGGYVNN 1530 Query: 331 GRVNGTINLSRAIGDMEFKQNKFLSPDKQMLTANPDVNTVELCDDDDFLVLACDGIWDCM 510 G+++G +++SRA+G + + + A+PD++ V L D+ L++A +W+ M Sbjct: 1531 GKLDGVVDVSRAVGFFDLLPH---------IHASPDISVVTLTKADEMLIVATHKLWEYM 1581 Query: 511 SSQQLVDFIHEH----------LKTESSLSAVCEKVLDRCLA 606 + D E+ LK + E + CLA Sbjct: 1582 DVDTVCDIARENSTDPLRAAAELKDHAMAYGCTENITILCLA 1623
>CYAA_SACKL (P23466) Adenylate cyclase (EC 4.6.1.1) (ATP pyrophosphate-lyase)| (Adenylyl cyclase) Length = 1839 Score = 75.1 bits (183), Expect = 2e-13 Identities = 48/177 (27%), Positives = 90/177 (50%), Gaps = 2/177 (1%) Frame = +1 Query: 154 GSTACVAMVRNSQLVVANAGDSRCVISRN-GQAYNLSRDHKPELEAERERILKAGGYIQM 330 GS+A V ++ ++ AN GD+ V+S+N G L++ H P E ERI +GGY+ Sbjct: 1286 GSSATVVYLKGKKIYTANIGDTMAVLSKNNGDFVTLTKLHVPAEREEYERIRTSGGYVNN 1345 Query: 331 GRVNGTINLSRAIGDMEFKQNKFLSPDKQMLTANPDVNTVELCDDDDFLVLACDGIWDCM 510 +++G +SRA+G + + + A+PD++ L D+ L++A +W+ + Sbjct: 1346 QKLDGVSEVSRAVGFFDLLPH---------IHASPDISETVLSYSDEMLIIATHKLWEYL 1396 Query: 511 SSQQLVDFIHEHLKTESSLSAVCEKVLDRCLAPSTLGGEGC-DNMTMILVQFKKPID 678 + + D E+ +S + EK+ D ++ GC DN+T++ V K ++ Sbjct: 1397 DYETVCDISREN---KSQPMSAAEKMKDYAIS------YGCSDNITILCVSLDKSVN 1444
>PDP1_HUMAN (Q9P0J1) [Pyruvate dehydrogenase [lipoamide]]-phosphatase 1,| mitochondrial precursor (EC 3.1.3.43) (PDP 1) (Pyruvate dehydrogenase phosphatase, catalytic subunit 1) (PDPC 1) (Protein phosphatase 2C) Length = 537 Score = 74.7 bits (182), Expect = 2e-13 Identities = 56/167 (33%), Positives = 78/167 (46%), Gaps = 35/167 (20%) Frame = +1 Query: 154 GSTACVAMVRNSQLVVANAGDSRCVISRNGQ-----AYNLSRDHKPELEAERERIL---- 306 G+TACVA V L VAN GDSR ++ + A LS DH + E E ER+ Sbjct: 271 GATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEHP 330 Query: 307 --KAGGYIQMGRVNGTINLSRAIGDMEFKQN---------------------KFLSPDKQ 417 +A ++ R+ G + RA GD++FK + KF+ P+ Sbjct: 331 KSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYH 390 Query: 418 M---LTANPDVNTVELCDDDDFLVLACDGIWDCMSSQQLVDFIHEHL 549 LTA P+V L D FLVLA DG+W+ M Q +V + E+L Sbjct: 391 TPPYLTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYL 437
>PDP1_MOUSE (Q3UV70) [Pyruvate dehydrogenase [lipoamide]]-phosphatase 1,| mitochondrial precursor (EC 3.1.3.43) (PDP 1) (Pyruvate dehydrogenase phosphatase, catalytic subunit 1) (PDPC 1) (Protein phosphatase 2C) Length = 538 Score = 74.7 bits (182), Expect = 2e-13 Identities = 56/167 (33%), Positives = 78/167 (46%), Gaps = 35/167 (20%) Frame = +1 Query: 154 GSTACVAMVRNSQLVVANAGDSRCVISRNGQ-----AYNLSRDHKPELEAERERIL---- 306 G+TACVA V L VAN GDSR ++ + A LS DH + E E ER+ Sbjct: 271 GATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEHP 330 Query: 307 --KAGGYIQMGRVNGTINLSRAIGDMEFKQN---------------------KFLSPDKQ 417 +A ++ R+ G + RA GD++FK + KF+ P+ Sbjct: 331 KNEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYH 390 Query: 418 M---LTANPDVNTVELCDDDDFLVLACDGIWDCMSSQQLVDFIHEHL 549 LTA P+V L D FLVLA DG+W+ M Q +V + E+L Sbjct: 391 TPPYLTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYL 437
>CYAA_USTMA (P49606) Adenylate cyclase (EC 4.6.1.1) (ATP pyrophosphate-lyase)| (Adenylyl cyclase) Length = 2493 Score = 74.3 bits (181), Expect = 3e-13 Identities = 49/128 (38%), Positives = 75/128 (58%), Gaps = 2/128 (1%) Frame = +1 Query: 154 GSTACVAMVRNSQLVVANAGDSRCVISRNG-QAYNLSRDHKPELEAERERILKAGGYIQM 330 G++A +A V + L +ANAGD+ V+SRNG A+ +S H+P AE ERI A G++ + Sbjct: 1846 GASAILAYVVDHTLYIANAGDALAVMSRNGGTAHLISNKHEPFDRAEIERIRSAEGWVSL 1905 Query: 331 -GRVNGTINLSRAIGDMEFKQNKFLSPDKQMLTANPDVNTVELCDDDDFLVLACDGIWDC 507 G VN +++SR+ G L P ++ A P V TV+L D D+F+++A +W Sbjct: 1906 RGYVNDMLDVSRSFGYFH------LFP---IVNAAPAVTTVQLTDSDEFVIIANRTLWQY 1956 Query: 508 MSSQQLVD 531 +S Q VD Sbjct: 1957 VSYQTAVD 1964
>PDP1_BOVIN (P35816) [Pyruvate dehydrogenase [lipoamide]]-phosphatase 1,| mitochondrial precursor (EC 3.1.3.43) (PDP 1) (Pyruvate dehydrogenase phosphatase, catalytic subunit 1) (PDPC 1) (Protein phosphatase 2C) Length = 538 Score = 74.3 bits (181), Expect = 3e-13 Identities = 56/167 (33%), Positives = 78/167 (46%), Gaps = 35/167 (20%) Frame = +1 Query: 154 GSTACVAMVRNSQLVVANAGDSRCVISRNGQ-----AYNLSRDHKPELEAERERIL---- 306 G+TACVA V L VAN GDSR ++ + A LS DH + E E ER+ Sbjct: 271 GATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNEREVERLKLEHP 330 Query: 307 --KAGGYIQMGRVNGTINLSRAIGDMEFKQN---------------------KFLSPD-- 411 +A ++ R+ G + RA GD++FK + KF+ P+ Sbjct: 331 KNEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYY 390 Query: 412 -KQMLTANPDVNTVELCDDDDFLVLACDGIWDCMSSQQLVDFIHEHL 549 LTA P+V L D FLVLA DG+W+ M Q +V + E+L Sbjct: 391 TPPYLTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYL 437
>PDP1_RAT (O88483) [Pyruvate dehydrogenase [lipoamide]]-phosphatase 1,| mitochondrial precursor (EC 3.1.3.43) (PDP 1) (Pyruvate dehydrogenase phosphatase, catalytic subunit 1) (PDPC 1) (Protein phosphatase 2C) Length = 538 Score = 73.6 bits (179), Expect = 5e-13 Identities = 55/167 (32%), Positives = 78/167 (46%), Gaps = 35/167 (20%) Frame = +1 Query: 154 GSTACVAMVRNSQLVVANAGDSRCVISRNGQ-----AYNLSRDHKPELEAERERIL---- 306 G+TACVA V L VAN GDSR ++ + A LS DH + E E +R+ Sbjct: 271 GATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELQRLKLEHP 330 Query: 307 --KAGGYIQMGRVNGTINLSRAIGDMEFKQN---------------------KFLSPDKQ 417 +A ++ R+ G + RA GD++FK + KF+ P+ Sbjct: 331 KNEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYH 390 Query: 418 M---LTANPDVNTVELCDDDDFLVLACDGIWDCMSSQQLVDFIHEHL 549 LTA P+V L D FLVLA DG+W+ M Q +V + E+L Sbjct: 391 TPPYLTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYL 437
>FEM2_CAEEL (P49594) Ca(2+)/calmodulin-dependent protein kinase phosphatase (EC| 3.1.3.16) (CaM-kinase phosphatase) (CaMKPase) (Sex-determining protein fem-2) (Feminization of XX and XO animals protein 2) Length = 449 Score = 69.3 bits (168), Expect = 1e-11 Identities = 52/181 (28%), Positives = 86/181 (47%), Gaps = 6/181 (3%) Frame = +1 Query: 154 GSTACVAMVRNSQLVVANA--GDSRCVISRNGQAYNLSRDHKPELEAERERILKAGGYIQ 327 GSTA + Q ++A A GDS + N + L+R H P E E R+ +AGG + Sbjct: 261 GSTAVCCAIDMDQKLMALAWLGDSPGYVMSNIEFRQLTRGHSPSDEREARRVEEAGGQLF 320 Query: 328 MG----RVNGTINLSRAIGDMEFKQNKFLSPDKQMLTANPDVNTVELCDDDDFLVLACDG 495 + RVNG +NL+RA+GD+ P + M++ P+ V + D ++LACDG Sbjct: 321 VIGGELRVNGVLNLTRALGDV---------PGRPMISNEPETCQVPIESSDYLVLLACDG 371 Query: 496 IWDCMSSQQLVDFIHEHLKTESSLSAVCEKVLDRCLAPSTLGGEGCDNMTMILVQFKKPI 675 I D + + L + E + + E L R + + DN+++++ + P Sbjct: 372 ISDVFNERDLYQLV-EAFANDYPVEDYAE--LSRFICTKAIEAGSADNVSVVIGFLRPPQ 428 Query: 676 D 678 D Sbjct: 429 D 429
>CYAA_NEUCR (Q01631) Adenylate cyclase (EC 4.6.1.1) (ATP pyrophosphate-lyase)| (Adenylyl cyclase) Length = 2300 Score = 67.4 bits (163), Expect = 4e-11 Identities = 50/153 (32%), Positives = 76/153 (49%), Gaps = 2/153 (1%) Frame = +1 Query: 154 GSTACVAMVRNSQLVVANAGDSR-CVISRNGQAYNLSRDHKPELEAERERILKAGGYI-Q 327 G A VA + +L VAN GD + +I NG L++ H P ER RI AGG++ + Sbjct: 1674 GCVATVAYLSELKLYVANVGDVQGMLIQANGSFKMLTKKHDPADPVERSRIRNAGGWVSR 1733 Query: 328 MGRVNGTINLSRAIGDMEFKQNKFLSPDKQMLTANPDVNTVELCDDDDFLVLACDGIWDC 507 GR+N +N+SRA G E L P Q A PD+ + D D+ +++A +W+ Sbjct: 1734 NGRLNDVLNVSRAFGYTE------LLPAVQ---AAPDITEHTIDDKDETVLIASKELWEH 1784 Query: 508 MSSQQLVDFIHEHLKTESSLSAVCEKVLDRCLA 606 + + +VD E S L +K+ D +A Sbjct: 1785 LRPELIVDVARE---CRSDLMKASQKLRDLAIA 1814
>PDP2_HUMAN (Q9P2J9) [Pyruvate dehydrogenase [lipoamide]]-phosphatase 2,| mitochondrial precursor (EC 3.1.3.43) (PDP 2) (Pyruvate dehydrogenase phosphatase, catalytic subunit 2) (PDPC 2) Length = 529 Score = 65.1 bits (157), Expect = 2e-10 Identities = 53/166 (31%), Positives = 73/166 (43%), Gaps = 34/166 (20%) Frame = +1 Query: 154 GSTACVAMVRNSQLVVANAGDSRCVIS---RNGQ--AYNLSRDHKPELEAERERILKAGG 318 G+TAC+A V L VANAGD R ++ NG L+RDH +AE R+ + Sbjct: 266 GATACMAHVDGIHLHVANAGDCRAILGVQEDNGMWSCLPLTRDHNAWNQAELSRLKREHP 325 Query: 319 ------YIQMGRVNGTINLSRAIGDMEFKQNKFLSPD----------------------- 411 I R+ G + RA GD++ K +K L Sbjct: 326 ESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQRSILERGFNTEALNIYQFTPPHYYT 385 Query: 412 KQMLTANPDVNTVELCDDDDFLVLACDGIWDCMSSQQLVDFIHEHL 549 LTA P+V L D FLVLA DG+WD +S++ +V + HL Sbjct: 386 PPYLTAEPEVTYHRLRPQDKFLVLASDGLWDMLSNEDVVRLVVGHL 431
>KAPP_ARATH (P46014) Kinase-associated protein phosphatase (EC 3.1.3.16)| Length = 581 Score = 63.9 bits (154), Expect = 4e-10 Identities = 50/160 (31%), Positives = 77/160 (48%), Gaps = 10/160 (6%) Frame = +1 Query: 154 GSTACVAMV-----RNSQLVVANAGDSRCVISRNGQAYNLSRDHKPELEAERERILKAGG 318 G TA V +V N AN GDS CVI G+ ++ DH+ +ER+R +AG Sbjct: 406 GCTATVLLVWKDNEENFFAQCANLGDSACVIHLGGRYIQMTEDHRVVSLSERKRFQEAGL 465 Query: 319 YIQMG--RVNGTINLSRAIGDMEFKQNKFLSPDKQMLTANPDVN---TVELCDDDDFLVL 483 ++ G R+ G INL+R +GD KF +A P ++ ++ D F VL Sbjct: 466 ALRDGETRLFG-INLARMLGD------KFPKQQDSRFSAEPYISEPLRIDQSSKDVFAVL 518 Query: 484 ACDGIWDCMSSQQLVDFIHEHLKTESSLSAVCEKVLDRCL 603 A DG+WD +S ++ V + + E + EK+ + L Sbjct: 519 ASDGLWDVVSPKKAVQLVLQMRDKERGRESSAEKIANGLL 558
>CYAA_PODAN (Q01513) Adenylate cyclase (EC 4.6.1.1) (ATP pyrophosphate-lyase)| (Adenylyl cyclase) Length = 2145 Score = 62.0 bits (149), Expect = 2e-09 Identities = 44/164 (26%), Positives = 81/164 (49%), Gaps = 2/164 (1%) Frame = +1 Query: 154 GSTACVAMVRNSQLVVANAGDSRCVISRNGQAY-NLSRDHKPELEAERERILKAGGYI-Q 327 G A + ++N L VAN GD + +I ++ + L++ H P ER RI +AGG++ + Sbjct: 1553 GGVATIVYIQNQDLYVANVGDVQAMIIKSDSTHVMLTKKHDPADPNERTRIREAGGWVSR 1612 Query: 328 MGRVNGTINLSRAIGDMEFKQNKFLSPDKQMLTANPDVNTVELCDDDDFLVLACDGIWDC 507 GR+N + +SRA G ++ L P Q + P++ + + D+ +++A +W+ Sbjct: 1613 NGRLNDLLEVSRAFGYLD------LMPAVQ---SAPNIEKHTIGEHDEMILIATREVWEY 1663 Query: 508 MSSQQLVDFIHEHLKTESSLSAVCEKVLDRCLAPSTLGGEGCDN 639 + LVD + ++ + +KV D +A GC N Sbjct: 1664 LPKDVLVD-VTRSVRQDPDPMRAAQKVRDLAMA------YGCSN 1700
>PDP2_RAT (O88484) [Pyruvate dehydrogenase [lipoamide]]-phosphatase 2,| mitochondrial precursor (EC 3.1.3.43) (PDP 2) (Pyruvate dehydrogenase phosphatase, catalytic subunit 2) (PDPC 2) Length = 530 Score = 61.6 bits (148), Expect = 2e-09 Identities = 50/166 (30%), Positives = 71/166 (42%), Gaps = 34/166 (20%) Frame = +1 Query: 154 GSTACVAMVRNSQLVVANAGDSRCVISRNGQ-----AYNLSRDHKPELEAERERILKAGG 318 G+TAC+A V L +ANAGD R ++ G L+ DH EAE R+ + Sbjct: 267 GATACMAHVDGVHLHIANAGDCRAILGVQGDNGAWSCLPLTCDHNAWNEAELSRLKREHP 326 Query: 319 ------YIQMGRVNGTINLSRAIGDMEFKQNKFLSPD----------------------- 411 I R+ G + RA GD++ K +K L + Sbjct: 327 ESEDRTLIIDDRLLGVLLPCRAFGDVQLKWSKELQRNVLERGFDTEALNIYQFTPPHYHT 386 Query: 412 KQMLTANPDVNTVELCDDDDFLVLACDGIWDCMSSQQLVDFIHEHL 549 LTA P+V L D FLVLA DG+WD + ++ +V + HL Sbjct: 387 PPYLTAKPEVTYHRLRPQDKFLVLASDGLWDMLDNEDVVRLVVGHL 432
>PHLPP_RAT (Q9WTR8) PH domain leucine-rich repeat protein phosphatase (EC| 3.1.3.16) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) Length = 1696 Score = 60.8 bits (146), Expect = 4e-09 Identities = 42/142 (29%), Positives = 67/142 (47%), Gaps = 9/142 (6%) Frame = +1 Query: 139 SGPTCGSTACVAMVRNSQ--------LVVANAGDSRCVISRNGQAYNLSRDHKPELEAER 294 +G G A + +R+ L AN G + V+ RNG+ +LSR + E ER Sbjct: 1220 AGQKLGGAAVLCHIRHDPVDLGGSFTLTSANVGKCQTVLCRNGKPLSLSRSYTMSCEEER 1279 Query: 295 ERILKAGGYI-QMGRVNGTINLSRAIGDMEFKQNKFLSPDKQMLTANPDVNTVELCDDDD 471 +RI + I + G+VNG +R +G FL P + P V +V L D+ Sbjct: 1280 KRIKQHKAIITEDGKVNGVTESTRILG------YTFLHPS---VVPRPHVQSVLLTPQDE 1330 Query: 472 FLVLACDGIWDCMSSQQLVDFI 537 F +L G+WD +S ++ V+ + Sbjct: 1331 FFILGSKGLWDSLSIEEAVEAV 1352
>PHLPP_MOUSE (Q8CHE4) PH domain leucine-rich repeat-containing protein phosphatase| (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory Length = 1687 Score = 58.9 bits (141), Expect = 1e-08 Identities = 38/116 (32%), Positives = 58/116 (50%), Gaps = 1/116 (0%) Frame = +1 Query: 193 LVVANAGDSRCVISRNGQAYNLSRDHKPELEAERERILKAGGYI-QMGRVNGTINLSRAI 369 L AN G + V+ RNG+ +LSR + E ER+RI + I + G+VNG +R + Sbjct: 1239 LTSANVGKCQTVLCRNGKPLSLSRSYIMSCEEERKRIKQHKAIITEDGKVNGVTESTRIL 1298 Query: 370 GDMEFKQNKFLSPDKQMLTANPDVNTVELCDDDDFLVLACDGIWDCMSSQQLVDFI 537 G FL P + P V +V L D+F +L G+WD +S + V+ + Sbjct: 1299 G------YTFLHPS---VVPRPHVQSVLLTPQDEFFILGSKGLWDSLSIDEAVEAV 1345
>PP2CD_HUMAN (O15297) Protein phosphatase 2C isoform delta (EC 3.1.3.16)| (PP2C-delta) (p53-induced protein phosphatase 1) (Protein phosphatase magnesium-dependent 1 delta) Length = 605 Score = 56.2 bits (134), Expect = 9e-08 Identities = 57/222 (25%), Positives = 97/222 (43%), Gaps = 44/222 (19%) Frame = +1 Query: 148 TCGSTACVAMVRNSQLVVANAGDSRCVISRNG-------QAYNLSRDHKPELEAERERIL 306 T G+TA V ++R ++ VA+ GDS V+ +A +++DHKPEL ERERI Sbjct: 170 TSGTTASVVIIRGMKMYVAHVGDSGVVLGIQDDPKDDFVRAVEVTQDHKPELPKERERIE 229 Query: 307 KAGGYIQ----MGRV---------NGTIN------------LSRAIGDM---EFKQNKFL 402 GG + + RV NG + ++RA+GD+ +F +F+ Sbjct: 230 GLGGSVMNKSGVNRVVWKRPRLTHNGPVRRSTVIDQIPFLAVARALGDLWSYDFFSGEFV 289 Query: 403 ---SPDKQMLTANPDVNTVELCDDDDFLVLACDGIWDCMSSQQLVDFIHE-----HLKTE 558 PD + T +P + +++L DG+W+ + Q + + +L E Sbjct: 290 VSPEPDTSVHTLDPQKH--------KYIILGSDGLWNMIPPQDAISMCQDQEEKKYLMGE 341 Query: 559 SSLSAVCEKVL-DRCLAPSTLGGEGCDNMTMILVQFKKPIDH 681 S C K+L +R L DN + I++ +D+ Sbjct: 342 HGQS--CAKMLVNRALGRWRQRMLRADNTSAIVICISPEVDN 381
>PP2CE_MOUSE (Q8BU27) Protein phosphatase 2C isoform eta (EC 3.1.3.16)| (PP2C-eta) (PP2CE) (Protein phosphatase 1M) Length = 406 Score = 56.2 bits (134), Expect = 9e-08 Identities = 51/209 (24%), Positives = 84/209 (40%), Gaps = 62/209 (29%) Frame = +1 Query: 109 AFEE-----GPHSDFSGPTCGSTACVAMVRNSQLVVANAGDSRCVISRNGQAYNLSRDHK 273 AF+E G + SG G TA VA+ +L VANAGDSR ++ R + LS + Sbjct: 141 AFQECDDVIGRELEASGQVGGCTALVAVFLQGKLYVANAGDSRAILVRRHEIRQLSSEFT 200 Query: 274 PELEAER----------------------------------------------ERILKAG 315 PE E +R +R+ K+ Sbjct: 201 PETERQRIQQLAFTYPELLAGEFTRLEFPRRLKGDDLGQKVLFRDHHMRGWSYKRVEKSD 260 Query: 316 -------GYIQMGRVNGTINLSRAIGDMEFKQNKFLSPDKQMLTANPDVNTVEL----CD 462 G + R+ GT+ +SR +GD + + K L + P V +++ Sbjct: 261 LKYPLIHGQGRQARLLGTLAVSRGLGDHQLRVLDTDIQLKPFLLSIPQVTVLDVHQLAVQ 320 Query: 463 DDDFLVLACDGIWDCMSSQQLVDFIHEHL 549 ++D +V+A DG+WD +S++Q+ + L Sbjct: 321 EEDVVVMATDGLWDVLSNEQVALLVRSFL 349
>PHLPP_HUMAN (O60346) PH domain leucine-rich repeat-containing protein phosphatase| (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory Length = 1717 Score = 55.8 bits (133), Expect = 1e-07 Identities = 37/116 (31%), Positives = 57/116 (49%), Gaps = 1/116 (0%) Frame = +1 Query: 193 LVVANAGDSRCVISRNGQAYNLSRDHKPELEAERERILKAGGYI-QMGRVNGTINLSRAI 369 L AN G + V+ RNG+ LSR + E E +RI + I + G+VNG +R + Sbjct: 1283 LTSANVGKCQTVLCRNGKPLPLSRSYIMSCEEELKRIKQHKAIITEDGKVNGVTESTRIL 1342 Query: 370 GDMEFKQNKFLSPDKQMLTANPDVNTVELCDDDDFLVLACDGIWDCMSSQQLVDFI 537 G FL P + P V +V L D+F +L G+WD +S ++ V+ + Sbjct: 1343 G------YTFLHPS---VVPRPHVQSVLLTPQDEFFILGSKGLWDSLSVEEAVEAV 1389
>PP2CD_MOUSE (Q9QZ67) Protein phosphatase 2C isoform delta (EC 3.1.3.16)| (PP2C-delta) (p53-induced protein phosphatase 1) (Protein phosphatase magnesium-dependent 1 delta) Length = 598 Score = 55.5 bits (132), Expect = 2e-07 Identities = 57/222 (25%), Positives = 97/222 (43%), Gaps = 44/222 (19%) Frame = +1 Query: 148 TCGSTACVAMVRNSQLVVANAGDSRCVISRNG-------QAYNLSRDHKPELEAERERIL 306 T G+TA V ++R ++ VA+ GDS V+ +A +++DHKPEL ERERI Sbjct: 163 TSGTTASVVIIRGMKMYVAHVGDSGVVLGIQDDPKDDFVRAVEVTQDHKPELPKERERIE 222 Query: 307 KAGGYIQ----MGRV---------NGTIN------------LSRAIGDM---EFKQNKFL 402 GG + + RV +G + ++RA+GD+ +F KF+ Sbjct: 223 GLGGSVMNKSGVNRVVWKRPRLTHSGPVRRSTVIDQIPFLAVARALGDLWSYDFFSGKFV 282 Query: 403 ---SPDKQMLTANPDVNTVELCDDDDFLVLACDGIWDCMSSQQLVDFIHE-----HLKTE 558 PD + T +P + +++L DG+W+ + Q + + +L E Sbjct: 283 VSPEPDTSVHTLDPRKH--------KYIILGSDGLWNMVPPQDAISMCQDQEEKKYLMGE 334 Query: 559 SSLSAVCEKVL-DRCLAPSTLGGEGCDNMTMILVQFKKPIDH 681 S C K+L +R L DN + I++ +D+ Sbjct: 335 QGQS--CAKMLVNRALGRWRQRMLRADNTSAIVICISPEVDN 374
>PP2CE_HUMAN (Q96MI6) Protein phosphatase 2C isoform eta (EC 3.1.3.16)| (PP2C-eta) (PP2CE) (Protein phosphatase 1M) Length = 270 Score = 55.1 bits (131), Expect = 2e-07 Identities = 51/209 (24%), Positives = 84/209 (40%), Gaps = 62/209 (29%) Frame = +1 Query: 109 AFEE-----GPHSDFSGPTCGSTACVAMVRNSQLVVANAGDSRCVISRNGQAYNLSRDHK 273 AF+E G + SG G TA VA+ +L +ANAGDSR ++ R + LS + Sbjct: 34 AFQECDEVIGRELEASGQMGGCTALVAVSLQGKLYMANAGDSRAILVRRDEIRPLSFEFT 93 Query: 274 PELEAER----------------------------------------------ERILKAG 315 PE E +R +R+ K+ Sbjct: 94 PETERQRIQQLAFVYPELLAGEFTRLEFPRRLKGDDLGQKVLFRDHHMSGWSYKRVEKSD 153 Query: 316 -------GYIQMGRVNGTINLSRAIGDMEFKQNKFLSPDKQMLTANPDVNTVEL----CD 462 G + R+ GT+ +SR +GD + + K L + P V +++ Sbjct: 154 LKYPLIHGQGRQARLLGTLAVSRGLGDHQLRVLDTNIQLKPFLLSVPQVTVLDVDQLELQ 213 Query: 463 DDDFLVLACDGIWDCMSSQQLVDFIHEHL 549 +DD +V+A DG+WD +S++Q+ + L Sbjct: 214 EDDVVVMATDGLWDVLSNEQVAWLVRSFL 242
>PP2C5_YEAST (Q12511) Protein phosphatase 2C homolog 5 (EC 3.1.3.16) (PP2C-5)| Length = 572 Score = 44.7 bits (104), Expect = 3e-04 Identities = 43/173 (24%), Positives = 78/173 (45%), Gaps = 32/173 (18%) Frame = +1 Query: 154 GSTACVAMVR--NSQLVVANAGDSRCVI-----SRNGQAYNLSRDHKPELEAERERILKA 312 GS A +++ NS L VA GDSR +I N +LS D + E RI K Sbjct: 280 GSCALLSLYNSTNSILKVAVTGDSRALICGLDNEGNWTVKSLSTDQTGDNLDEVRRIRKE 339 Query: 313 G----GYIQMGRVNGTINLSRAIGDMEFK----QNKFLSPDKQM---------------- 420 I+ GR+ G++ SRA GD +K K LS ++ Sbjct: 340 HPGEPNVIRNGRILGSLQPSRAFGDYRYKIKEVDGKPLSDLPEVAKLYFRREPRDFKTPP 399 Query: 421 -LTANPDVNTVELCDDDDFLVLACDGIWDCMSSQQLVDFIHEHLKTESSLSAV 576 +TA P + + ++ ++ F+V+ DG+++ ++++++ + + +L+ V Sbjct: 400 YVTAEPVITSAKIGENTKFMVMGSDGLFELLTNEEIASLVIRWMDKNMNLAPV 452
>CYAA_SCHPO (P14605) Adenylate cyclase (EC 4.6.1.1) (ATP pyrophosphate-lyase)| (Adenylyl cyclase) Length = 1692 Score = 42.7 bits (99), Expect = 0.001 Identities = 41/143 (28%), Positives = 69/143 (48%), Gaps = 2/143 (1%) Frame = +1 Query: 115 EEGPHSDFSGPTCGSTACVAMVRNSQLVVANAGDSRCVIS--RNGQAYNLSRDHKPELEA 288 E+G D S G + + VR+++ VAN G S ++S + + LS H Sbjct: 1111 EKGYSMDSSCLDIGVSIILVYVRDTRAFVANVGTSMAIMSTRNDSEPTTLSVMHDVYNRD 1170 Query: 289 ERERILKAGGYIQMGRVNGTINLSRAIGDMEFKQNKFLSPDKQMLTANPDVNTVELCDDD 468 E RI+ + G+I G + T +RAIG + ++F P Q A P VN L + + Sbjct: 1171 EIRRIVDSCGFIS-GEIKST--TTRAIG----RLSQF--PGVQ---AVPYVNVQYLSELN 1218 Query: 469 DFLVLACDGIWDCMSSQQLVDFI 537 +F++LA W +S + ++D + Sbjct: 1219 EFIILANQEFWSVLSKRTVIDVV 1241
>PHLPP_DROME (Q9VJ07) Protein phosphatase PHLPP-like protein (EC 3.1.3.16)| (dPHLPP) Length = 954 Score = 34.3 bits (77), Expect = 0.36 Identities = 36/173 (20%), Positives = 75/173 (43%), Gaps = 5/173 (2%) Frame = +1 Query: 178 VRNSQLVVANAGDSRCVISRNGQAYNLSRDHKPELEAERERILKAGGYIQMGRVNGTIN- 354 VR+ A +C R+ ++L+R P + R LK+ Y+ G ++ Sbjct: 505 VRDYMKFTLLAAQQQCGSVRSAALFHLTRTRAPS----KVRPLKSKRYVLRMASTGGLDA 560 Query: 355 -LSRAIGDMEFKQNKFLSPDKQMLTANPDVNTVELCDDDDFLVLACDGIWDCMSSQQLVD 531 L R + + + D+ +P V + L +DD++LV+ +W M +D Sbjct: 561 YLIRRTSQLRLTKPDVIQKDQIHSMPDPHVLELILSNDDEYLVVGNAQLWSVMD----ID 616 Query: 532 FIHEHLKTESSLSAVCEKVLDRCLAPSTLGGEGCDNMTMILVQFK---KPIDH 681 ++ E + ++++D +A S E ++++I+V+F+ +DH Sbjct: 617 RAAREIRKEENSLLAAKRLVD--IAQSFAAAE---SLSVIVVRFRHLGTDVDH 664
>CXA10_HUMAN (P57773) Gap junction alpha-10 protein (Connexin-59) (Cx59)| (Connexin-58) (Cx58) Length = 515 Score = 32.7 bits (73), Expect = 1.0 Identities = 16/59 (27%), Positives = 32/59 (54%) Frame = -3 Query: 223 SGNLRRLPQQVDYSLPLQHRLYSRRLAR*NQSEVPPQKPNHHVYHLNHCLSETRSTLLS 47 + +L+RLP DY+L ++ + ++ N S V P++H + C+ + + T+LS Sbjct: 272 ANSLKRLPSAPDYNLLVEKQTHTAVYPSLNSSSVFQPNPDNHSVNDEKCILDEQETVLS 330
>BSU1_ARATH (Q9LR78) Serine/threonine-protein phosphatase BSU1 (EC 3.1.3.16)| (Bri1 suppressor protein 1) Length = 793 Score = 31.2 bits (69), Expect = 3.1 Identities = 14/45 (31%), Positives = 20/45 (44%) Frame = +1 Query: 133 DFSGPTCGSTACVAMVRNSQLVVANAGDSRCVISRNGQAYNLSRD 267 D+ GP CG T V NS ++ G + V + N +S D Sbjct: 26 DWPGPRCGHTLTAVFVNNSHQLILFGGSTTAVANHNSSLPEISLD 70
>KCY_STRP6 (Q5XCU3) Cytidylate kinase (EC 2.7.4.14) (CK) (Cytidine| monophosphate kinase) (CMP kinase) Length = 226 Score = 31.2 bits (69), Expect = 3.1 Identities = 24/65 (36%), Positives = 32/65 (49%), Gaps = 5/65 (7%) Frame = +1 Query: 187 SQLVVANAGDSRCVISRNGQAYNLS-----RDHKPELEAERERILKAGGYIQMGRVNGTI 351 SQLV D VI +N N+S + + EL ++ RI +AGG I GR GT+ Sbjct: 76 SQLVFLGDEDVTLVIRQNDVTNNVSWVSALPEIREELVHQQRRIAQAGGIIMDGRDIGTV 135 Query: 352 NLSRA 366 L A Sbjct: 136 VLPDA 140
>HIRA_FUGRU (O42611) HIRA protein (TUP1-like enhancer of split protein 1)| Length = 1025 Score = 30.4 bits (67), Expect = 5.2 Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 18/91 (19%) Frame = +1 Query: 40 TGMIEGLIWSPRG----SDSND------RHDDWAFEEGPHSDFSGPTCGSTACVAMVR-- 183 TG+++GL W P G S ++D R DW E FS CG T V + Sbjct: 174 TGLVKGLTWDPVGKYIASQADDHSLRVWRTVDWQMEANITKPFS--ECGGTTHVLRLSWS 231 Query: 184 -NSQLVVA-----NAGDSRCVISRNGQAYNL 258 + Q +V+ N+G + ++ R+G N+ Sbjct: 232 PDGQYLVSAHAMNNSGPTAQIVERDGWRTNM 262
>PRMA_THET8 (Q84BQ9) Ribosomal protein L11 methyltransferase (EC 2.1.1.-) (L11| Mtase) Length = 254 Score = 30.0 bits (66), Expect = 6.8 Identities = 14/29 (48%), Positives = 18/29 (62%) Frame = +2 Query: 200 WQTPEIPAVLSQGMARHTIYQETTNQSLK 286 W+ EIP V+ GMA T + ETT +LK Sbjct: 84 WEGAEIPLVIEPGMAFGTGHHETTRLALK 112
>RUSC2_MOUSE (Q80U22) RUN and SH3 domain-containing protein 2| Length = 1514 Score = 30.0 bits (66), Expect = 6.8 Identities = 17/46 (36%), Positives = 26/46 (56%) Frame = +1 Query: 271 KPELEAERERILKAGGYIQMGRVNGTINLSRAIGDMEFKQNKFLSP 408 +PELEAER + + GG+ G GT ++S + E+K + SP Sbjct: 190 RPELEAERMELDECGGHGGSGSGGGTSDISGFSFEQEWKISSDESP 235
>DCR1_DROME (Q9VCU9) Endoribonuclease Dcr-1 (EC 3.1.26.-) (Protein dicer-1)| Length = 2249 Score = 29.6 bits (65), Expect = 8.9 Identities = 12/33 (36%), Positives = 21/33 (63%) Frame = -1 Query: 408 RRQEFILFKFHISNCS*QVYSSIYSPHLDVPPC 310 RRQE +L +F + +C+ + +S+ +DVP C Sbjct: 549 RRQEEVLKRFRMHDCNVLIGTSVLEEGIDVPKC 581
>KCY_STRP8 (Q8P1H8) Cytidylate kinase (EC 2.7.4.14) (CK) (Cytidine| monophosphate kinase) (CMP kinase) Length = 226 Score = 29.6 bits (65), Expect = 8.9 Identities = 23/65 (35%), Positives = 31/65 (47%), Gaps = 5/65 (7%) Frame = +1 Query: 187 SQLVVANAGDSRCVISRNGQAYNLS-----RDHKPELEAERERILKAGGYIQMGRVNGTI 351 SQLV D I +N N+S + + EL ++ RI +AGG I GR GT+ Sbjct: 76 SQLVFLGDEDVTLAIRQNDVTNNVSWVSALPEIREELVHQQRRIAQAGGIIMDGRDIGTV 135 Query: 352 NLSRA 366 L A Sbjct: 136 VLPDA 140
>KCY_STRP3 (Q8K7Z9) Cytidylate kinase (EC 2.7.4.14) (CK) (Cytidine| monophosphate kinase) (CMP kinase) Length = 226 Score = 29.6 bits (65), Expect = 8.9 Identities = 23/65 (35%), Positives = 31/65 (47%), Gaps = 5/65 (7%) Frame = +1 Query: 187 SQLVVANAGDSRCVISRNGQAYNLS-----RDHKPELEAERERILKAGGYIQMGRVNGTI 351 SQLV D I +N N+S + + EL ++ RI +AGG I GR GT+ Sbjct: 76 SQLVFLGDEDVTLAIRQNDVTNNVSWVSALPEIREELVHQQRRIAQAGGIIMDGRDIGTV 135 Query: 352 NLSRA 366 L A Sbjct: 136 VLPDA 140
>KCY_STRP1 (Q9A0F0) Cytidylate kinase (EC 2.7.4.14) (CK) (Cytidine| monophosphate kinase) (CMP kinase) Length = 226 Score = 29.6 bits (65), Expect = 8.9 Identities = 23/65 (35%), Positives = 31/65 (47%), Gaps = 5/65 (7%) Frame = +1 Query: 187 SQLVVANAGDSRCVISRNGQAYNLS-----RDHKPELEAERERILKAGGYIQMGRVNGTI 351 SQLV D I +N N+S + + EL ++ RI +AGG I GR GT+ Sbjct: 76 SQLVFLGDEDVTLAIRQNDVTNNVSWISALPEIREELVHQQRRIAQAGGIIMDGRDIGTV 135 Query: 352 NLSRA 366 L A Sbjct: 136 VLPDA 140 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 102,662,690 Number of Sequences: 219361 Number of extensions: 2135679 Number of successful extensions: 6508 Number of sequences better than 10.0: 65 Number of HSP's better than 10.0 without gapping: 5895 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6382 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 6712189044 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
