ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bags30e10 |
|---|---|
| Clone Library Name | barley_pub |
>ACOC_CUCMA (P49608) Aconitate hydratase, cytoplasmic (EC 4.2.1.3) (Citrate| hydro-lyase) (Aconitase) Length = 898 Score = 412 bits (1059), Expect = e-115 Identities = 198/229 (86%), Positives = 215/229 (93%) Frame = +1 Query: 13 VVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQ 192 VVIAAITSCTNTSNP+VMLGAALVAKKAC+LGL+VKPW+KTSLAPGSGVV KYL KSGLQ Sbjct: 433 VVIAAITSCTNTSNPSVMLGAALVAKKACELGLQVKPWVKTSLAPGSGVVTKYLLKSGLQ 492 Query: 193 KYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRA 372 YLNQ GF+IVGYGCTTCIGNSGDLDESV+AAI+DND+VAAAVLSGNRNFEGRVH LTRA Sbjct: 493 PYLNQQGFHIVGYGCTTCIGNSGDLDESVSAAISDNDIVAAAVLSGNRNFEGRVHPLTRA 552 Query: 373 NYLASPPLVVAYALAGTVNIDFEKEPVGISKDGKEVYFRDIWPSTDEIAEVVKSSVLPDM 552 NYLASPPLVVAYALAGTV+IDFEKEP+G KDGK+VYFRDIWPST+EIAEVV+SSVLPDM Sbjct: 553 NYLASPPLVVAYALAGTVDIDFEKEPIGKGKDGKDVYFRDIWPSTEEIAEVVQSSVLPDM 612 Query: 553 FKGTYEAITKGNPMWNELPVSASTLYPWDPKSTYIHEPPYFKDMTMTPP 699 FK TYE+ITKGNPMWN+L V + TLY WDP STYIHEPPYFK+MTM PP Sbjct: 613 FKSTYESITKGNPMWNQLSVPSGTLYSWDPNSTYIHEPPYFKNMTMDPP 661
>ACOC_SOLTU (O04916) Aconitate hydratase, cytoplasmic (EC 4.2.1.3) (Citrate| hydro-lyase) (Aconitase) (Fragment) Length = 616 Score = 411 bits (1057), Expect = e-115 Identities = 199/229 (86%), Positives = 214/229 (93%) Frame = +1 Query: 13 VVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQ 192 VVIAAITSCTNTSNP+VMLGAALVAKKA +LGL VKPW+KTSLAPGSGVV KYL KSGLQ Sbjct: 151 VVIAAITSCTNTSNPSVMLGAALVAKKASELGLHVKPWVKTSLAPGSGVVTKYLLKSGLQ 210 Query: 193 KYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRA 372 KYLNQ GFNIVGYGCTTCIGNSGDLDESVA+AI++ND+VAAAVLSGNRNFEGRVHALTRA Sbjct: 211 KYLNQQGFNIVGYGCTTCIGNSGDLDESVASAISENDIVAAAVLSGNRNFEGRVHALTRA 270 Query: 373 NYLASPPLVVAYALAGTVNIDFEKEPVGISKDGKEVYFRDIWPSTDEIAEVVKSSVLPDM 552 NYLASPPLVVAYALAGTV+IDFEK+P+G+ KDGK+VYFRDIWPST+EIAEVV+SSVLPDM Sbjct: 271 NYLASPPLVVAYALAGTVDIDFEKDPIGVGKDGKDVYFRDIWPSTEEIAEVVQSSVLPDM 330 Query: 553 FKGTYEAITKGNPMWNELPVSASTLYPWDPKSTYIHEPPYFKDMTMTPP 699 FK TYEAITKGN MWNEL V + LY WDPKSTYIHEPPYFK MTM PP Sbjct: 331 FKSTYEAITKGNTMWNELSVPTTKLYQWDPKSTYIHEPPYFKGMTMDPP 379
>ACOC_ARATH (Q42560) Aconitate hydratase, cytoplasmic (EC 4.2.1.3) (Citrate| hydro-lyase) (Aconitase) Length = 898 Score = 406 bits (1044), Expect = e-113 Identities = 194/229 (84%), Positives = 213/229 (93%) Frame = +1 Query: 13 VVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQ 192 VVIAAITSCTNTSNP+VMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVV KYL KSGLQ Sbjct: 433 VVIAAITSCTNTSNPSVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVTKYLAKSGLQ 492 Query: 193 KYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRA 372 KYLNQLGF+IVGYGCTTCIGNSGD+ E+VA+AI DND+VA+AVLSGNRNFEGRVH LTRA Sbjct: 493 KYLNQLGFSIVGYGCTTCIGNSGDIHEAVASAIVDNDLVASAVLSGNRNFEGRVHPLTRA 552 Query: 373 NYLASPPLVVAYALAGTVNIDFEKEPVGISKDGKEVYFRDIWPSTDEIAEVVKSSVLPDM 552 NYLASPPLVVAYALAGTV+IDFE +P+G KDGK+++FRDIWPS E+AEVV+SSVLPDM Sbjct: 553 NYLASPPLVVAYALAGTVDIDFETQPIGTGKDGKQIFFRDIWPSNKEVAEVVQSSVLPDM 612 Query: 553 FKGTYEAITKGNPMWNELPVSASTLYPWDPKSTYIHEPPYFKDMTMTPP 699 FK TYEAITKGN MWN+L V++ TLY WDPKSTYIHEPPYFK MTM+PP Sbjct: 613 FKATYEAITKGNSMWNQLSVASGTLYEWDPKSTYIHEPPYFKGMTMSPP 661
>ACOC_CUCMC (Q42669) Aconitase (EC 4.2.1.3) (Aconitate hydratase) (Citrate| hydro-lyase) (Fragment) Length = 764 Score = 379 bits (973), Expect = e-105 Identities = 184/229 (80%), Positives = 205/229 (89%) Frame = +1 Query: 13 VVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQ 192 VVIAAITSCTNTS+ +VMLGAALVAKKAC+LGLEVKPWIKT L GVV KYL KSGLQ Sbjct: 299 VVIAAITSCTNTSS-SVMLGAALVAKKACELGLEVKPWIKTVLLQALGVVTKYLAKSGLQ 357 Query: 193 KYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRA 372 KYLNQLGFNIVGYGCTTCIGNSGD+DESVA+AIT ND+VAAAVLSGNRNFEGRVH LTRA Sbjct: 358 KYLNQLGFNIVGYGCTTCIGNSGDIDESVASAITGNDIVAAAVLSGNRNFEGRVHPLTRA 417 Query: 373 NYLASPPLVVAYALAGTVNIDFEKEPVGISKDGKEVYFRDIWPSTDEIAEVVKSSVLPDM 552 NYLASPPLVVAYALAGTV+IDFE EP+G+ KDGK+V+FRDIWP+++E+A VV S+VLPDM Sbjct: 418 NYLASPPLVVAYALAGTVDIDFESEPIGVGKDGKKVFFRDIWPTSEEVAVVVNSNVLPDM 477 Query: 553 FKGTYEAITKGNPMWNELPVSASTLYPWDPKSTYIHEPPYFKDMTMTPP 699 F+ TY+AIT+GN WN L V TLY WDP STYIHEPPYFKDM+M+PP Sbjct: 478 FRATYQAITEGNATWNLLSVPEGTLYSWDPTSTYIHEPPYFKDMSMSPP 526
>IREB1_RAT (Q63270) Iron-responsive element-binding protein 1 (IRE-BP 1) (Iron| regulatory protein 1) (IRP1) (Ferritin repressor protein) (Aconitate hydratase) (EC 4.2.1.3) (Citrate hydro-lyase) (Aconitase) Length = 889 Score = 307 bits (786), Expect = 2e-83 Identities = 146/226 (64%), Positives = 177/226 (78%) Frame = +1 Query: 13 VVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQ 192 VVIAAITSCTNTSNP+VMLGA L+AKKA + GL VKP++KTSL+PGSGVV YL +SG+ Sbjct: 429 VVIAAITSCTNTSNPSVMLGAGLLAKKAVEAGLNVKPYVKTSLSPGSGVVTYYLRESGVM 488 Query: 193 KYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRA 372 YL+QLGF++VGYGC TCIGNSG L E V AIT D+VA VLSGNRNFEGRVH TRA Sbjct: 489 PYLSQLGFDVVGYGCMTCIGNSGPLPEPVVEAITQGDLVAVGVLSGNRNFEGRVHPNTRA 548 Query: 373 NYLASPPLVVAYALAGTVNIDFEKEPVGISKDGKEVYFRDIWPSTDEIAEVVKSSVLPDM 552 NYLASPPLV+AYA+AGTV IDFEKEP+G++ G++V+ +DIWP+ DEI EV + V+P M Sbjct: 549 NYLASPPLVIAYAIAGTVRIDFEKEPLGVNAQGQQVFLKDIWPTRDEIQEVERKYVIPGM 608 Query: 553 FKGTYEAITKGNPMWNELPVSASTLYPWDPKSTYIHEPPYFKDMTM 690 FK Y+ I N WN L + LY W+PKSTYI PP+F+ +T+ Sbjct: 609 FKEVYQKIETVNKSWNALAAPSEKLYAWNPKSTYIKSPPFFESLTL 654
>IREB1_MOUSE (P28271) Iron-responsive element-binding protein 1 (IRE-BP 1) (Iron| regulatory protein 1) (IRP1) (Ferritin repressor protein) (Aconitate hydratase) (EC 4.2.1.3) (Citrate hydro-lyase) (Aconitase) Length = 889 Score = 305 bits (782), Expect = 7e-83 Identities = 146/226 (64%), Positives = 176/226 (77%) Frame = +1 Query: 13 VVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQ 192 VVIAAITSCTNTSNP+VMLGA L+AKKA + GL VKP+IKTSL+PGSGVV YL +SG+ Sbjct: 429 VVIAAITSCTNTSNPSVMLGAGLLAKKAVEAGLSVKPYIKTSLSPGSGVVTYYLRESGVM 488 Query: 193 KYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRA 372 YL+QLGF++VGYGC TCIGNSG L E V AIT D+VA VLSGNRNFEGRVH TRA Sbjct: 489 PYLSQLGFDVVGYGCMTCIGNSGPLPEPVVEAITQGDLVAVGVLSGNRNFEGRVHPNTRA 548 Query: 373 NYLASPPLVVAYALAGTVNIDFEKEPVGISKDGKEVYFRDIWPSTDEIAEVVKSSVLPDM 552 NYLASPPLV+AYA+AGTV IDFEKEP+G++ G++V+ +DIWP+ DEI V + V+P M Sbjct: 549 NYLASPPLVIAYAIAGTVRIDFEKEPLGVNAQGRQVFLKDIWPTRDEIQAVERQYVIPGM 608 Query: 553 FKGTYEAITKGNPMWNELPVSASTLYPWDPKSTYIHEPPYFKDMTM 690 FK Y+ I N WN L + LY W+PKSTYI PP+F+ +T+ Sbjct: 609 FKEVYQKIETVNKSWNALAAPSEKLYAWNPKSTYIKSPPFFESLTL 654
>IREB1_CHICK (Q90875) Iron-responsive element binding protein (IRE-BP) (Iron| regulatory protein) (IRP) (Ferritin repressor protein) (Aconitate hydratase) (EC 4.2.1.3) (Citrate hydro-lyase) (Aconitase) Length = 889 Score = 305 bits (781), Expect = 9e-83 Identities = 147/226 (65%), Positives = 176/226 (77%) Frame = +1 Query: 13 VVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQ 192 VVIAAITSCTNTSNP+VMLGA L+AKKA + GL VKP+IKTSL+PGSGVV YL +SG+ Sbjct: 429 VVIAAITSCTNTSNPSVMLGAGLLAKKAVEAGLTVKPYIKTSLSPGSGVVTYYLRESGVM 488 Query: 193 KYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRA 372 YL+QLGF++VGYGC TCIGNSG L +SV AIT D+VA VLSGNRNFEGRVH TRA Sbjct: 489 SYLSQLGFDVVGYGCMTCIGNSGPLPDSVVEAITQGDLVAVGVLSGNRNFEGRVHPNTRA 548 Query: 373 NYLASPPLVVAYALAGTVNIDFEKEPVGISKDGKEVYFRDIWPSTDEIAEVVKSSVLPDM 552 NYLASPPLV+AYA+AGTV IDFEKEP+GIS GK+++ +DIWP+ +EI V + V+P M Sbjct: 549 NYLASPPLVIAYAIAGTVRIDFEKEPLGISASGKKIFLKDIWPTRNEIQAVERQYVIPGM 608 Query: 553 FKGTYEAITKGNPMWNELPVSASTLYPWDPKSTYIHEPPYFKDMTM 690 FK Y+ I N WN L + LY W+PKSTYI PP+F +T+ Sbjct: 609 FKEVYQKIETVNEAWNALDAPSDKLYTWNPKSTYIKSPPFFDGLTL 654
>IREB1_RABIT (Q01059) Iron-responsive element-binding protein 1 (IRE-BP 1) (Iron| regulatory protein 1) (IRP1) (Ferritin repressor protein) (Aconitate hydratase) (EC 4.2.1.3) (Citrate hydro-lyase) (Aconitase) Length = 889 Score = 301 bits (770), Expect = 2e-81 Identities = 144/226 (63%), Positives = 175/226 (77%) Frame = +1 Query: 13 VVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQ 192 VVIAAITSCTNTSNP+VMLGA L+AKKA D GL VKP++KTSL+PGSGVV YL +SG+ Sbjct: 429 VVIAAITSCTNTSNPSVMLGAGLLAKKAVDAGLNVKPYVKTSLSPGSGVVTYYLRESGVM 488 Query: 193 KYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRA 372 YL+QLGF++VGYGC TCIGNSG L E V AIT D+VA VLSGNRNFEGRVH TRA Sbjct: 489 PYLSQLGFDVVGYGCMTCIGNSGPLPEPVVEAITQGDLVAVGVLSGNRNFEGRVHPNTRA 548 Query: 373 NYLASPPLVVAYALAGTVNIDFEKEPVGISKDGKEVYFRDIWPSTDEIAEVVKSSVLPDM 552 NYLASPPLV+AYA+AGT+ IDFEKEP+G + G++V+ RDIWP+ +EI V + V+P M Sbjct: 549 NYLASPPLVIAYAIAGTIRIDFEKEPLGTNAKGQQVFLRDIWPTREEIQAVERQYVIPGM 608 Query: 553 FKGTYEAITKGNPMWNELPVSASTLYPWDPKSTYIHEPPYFKDMTM 690 F Y+ I N WN L + LY W+PKSTYI PP+F+++T+ Sbjct: 609 FTEVYQKIETVNASWNALAAPSDKLYLWNPKSTYIKSPPFFENLTL 654
>IREB1_HUMAN (P21399) Iron-responsive element-binding protein 1 (IRE-BP 1) (Iron| regulatory protein 1) (IRP1) (Ferritin repressor protein) (Aconitate hydratase) (EC 4.2.1.3) (Citrate hydro-lyase) (Aconitase) Length = 889 Score = 299 bits (765), Expect = 6e-81 Identities = 143/226 (63%), Positives = 175/226 (77%) Frame = +1 Query: 13 VVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQ 192 VVIAAITSCTNTSNP+VMLGA L+AKKA D GL V P+IKTSL+PGSGVV YL +SG+ Sbjct: 429 VVIAAITSCTNTSNPSVMLGAGLLAKKAVDAGLNVMPYIKTSLSPGSGVVTYYLQESGVM 488 Query: 193 KYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRA 372 YL+QLGF++VGYGC TCIGNSG L E V AIT D+VA VLSGNRNFEGRVH TRA Sbjct: 489 PYLSQLGFDVVGYGCMTCIGNSGPLPEPVVEAITQGDLVAVGVLSGNRNFEGRVHPNTRA 548 Query: 373 NYLASPPLVVAYALAGTVNIDFEKEPVGISKDGKEVYFRDIWPSTDEIAEVVKSSVLPDM 552 NYLASPPLV+AYA+AGT+ IDFEKEP+G++ G++V+ +DIWP+ DEI V + V+P M Sbjct: 549 NYLASPPLVIAYAIAGTIRIDFEKEPLGVNAKGQQVFLKDIWPTRDEIQAVERQYVIPGM 608 Query: 553 FKGTYEAITKGNPMWNELPVSASTLYPWDPKSTYIHEPPYFKDMTM 690 FK Y+ I N WN L + L+ W+ KSTYI PP+F+++T+ Sbjct: 609 FKEVYQKIETVNESWNALATPSDKLFFWNSKSTYIKSPPFFENLTL 654
>ACON_BACSU (P09339) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 908 Score = 294 bits (752), Expect = 2e-79 Identities = 136/228 (59%), Positives = 172/228 (75%) Frame = +1 Query: 13 VVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQ 192 + IAAITSCTNTSNP V++GA LVAKKA +LGL+V ++KTSLAPGS VV YL SGL Sbjct: 441 IAIAAITSCTNTSNPYVLIGAGLVAKKAVELGLKVPNYVKTSLAPGSKVVTGYLVNSGLL 500 Query: 193 KYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRA 372 Y+ +LGFN+VGYGCTTCIGNSG L + A+ ND++ +VLSGNRNFEGR+H L + Sbjct: 501 PYMKELGFNLVGYGCTTCIGNSGPLSPEIEEAVAKNDLLITSVLSGNRNFEGRIHPLVKG 560 Query: 373 NYLASPPLVVAYALAGTVNIDFEKEPVGISKDGKEVYFRDIWPSTDEIAEVVKSSVLPDM 552 NYLASPPLVVAYALAGTVNI+ + +P+G+ KDG+ VYF DIWPS DEI +VK +V P++ Sbjct: 561 NYLASPPLVVAYALAGTVNINLKTDPIGVGKDGQNVYFNDIWPSMDEINALVKQTVTPEL 620 Query: 553 FKGTYEAITKGNPMWNELPVSASTLYPWDPKSTYIHEPPYFKDMTMTP 696 F+ YE + N WNE+ + LY WD STYI PP+F++M++ P Sbjct: 621 FRKEYETVFDDNKRWNEIETTDEALYKWDNDSTYIQNPPFFEEMSVEP 668
>ACON_STAES (Q8CPC2) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 901 Score = 285 bits (728), Expect = 1e-76 Identities = 136/228 (59%), Positives = 170/228 (74%) Frame = +1 Query: 13 VVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQ 192 + IAAITSCTNTSNP VMLGA LVAKKA + GL+V ++KTSLAPGS VV YL SGLQ Sbjct: 435 IAIAAITSCTNTSNPYVMLGAGLVAKKAVEKGLKVPEFVKTSLAPGSKVVTGYLRDSGLQ 494 Query: 193 KYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRA 372 +YL+ LGFN+VGYGCTTCIGNSG L + A+ D D++ +VLSGNRNFEGR+H L +A Sbjct: 495 QYLDDLGFNLVGYGCTTCIGNSGPLLPEIEKAVADEDLLVTSVLSGNRNFEGRIHPLVKA 554 Query: 373 NYLASPPLVVAYALAGTVNIDFEKEPVGISKDGKEVYFRDIWPSTDEIAEVVKSSVLPDM 552 NYLASP LVVAYALAGTV+ID + EP+G KDGK+VY +DIWPS E+++ V V P++ Sbjct: 555 NYLASPQLVVAYALAGTVDIDLQNEPIGKGKDGKDVYLQDIWPSIQEVSDTVDKVVTPEL 614 Query: 553 FKGTYEAITKGNPMWNELPVSASTLYPWDPKSTYIHEPPYFKDMTMTP 696 F Y+ + N MWNE+ V+ LY +DP STYI P +F+ ++ P Sbjct: 615 FLEEYKNVYHNNEMWNEIDVTDEPLYDFDPNSTYIQNPTFFQGLSKEP 662
>ACON_STAEQ (Q5HPJ0) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 901 Score = 285 bits (728), Expect = 1e-76 Identities = 136/228 (59%), Positives = 170/228 (74%) Frame = +1 Query: 13 VVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQ 192 + IAAITSCTNTSNP VMLGA LVAKKA + GL+V ++KTSLAPGS VV YL SGLQ Sbjct: 435 IAIAAITSCTNTSNPYVMLGAGLVAKKAVEKGLKVPEFVKTSLAPGSKVVTGYLRDSGLQ 494 Query: 193 KYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRA 372 +YL+ LGFN+VGYGCTTCIGNSG L + A+ D D++ +VLSGNRNFEGR+H L +A Sbjct: 495 QYLDDLGFNLVGYGCTTCIGNSGPLLPEIEKAVADEDLLVTSVLSGNRNFEGRIHPLVKA 554 Query: 373 NYLASPPLVVAYALAGTVNIDFEKEPVGISKDGKEVYFRDIWPSTDEIAEVVKSSVLPDM 552 NYLASP LVVAYALAGTV+ID + EP+G KDGK+VY +DIWPS E+++ V V P++ Sbjct: 555 NYLASPQLVVAYALAGTVDIDLQNEPIGKGKDGKDVYLQDIWPSIQEVSDTVDKVVTPEL 614 Query: 553 FKGTYEAITKGNPMWNELPVSASTLYPWDPKSTYIHEPPYFKDMTMTP 696 F Y+ + N MWNE+ V+ LY +DP STYI P +F+ ++ P Sbjct: 615 FLEEYKNVYHNNEMWNEIDVTDEPLYDFDPNSTYIQNPTFFQGLSKEP 662
>ACON_STAAW (P63434) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 901 Score = 280 bits (716), Expect = 3e-75 Identities = 134/228 (58%), Positives = 168/228 (73%) Frame = +1 Query: 13 VVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQ 192 + IAAITSCTNTSNP VMLGA LVAKKA + GL+V ++KTSLAPGS VV YL +GLQ Sbjct: 435 IAIAAITSCTNTSNPYVMLGAGLVAKKAVEKGLKVPEYVKTSLAPGSKVVTGYLRDAGLQ 494 Query: 193 KYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRA 372 YL+ LGFN+VGYGCTTCIGNSG L + AI D D++ +VLSGNRNFEGR+H L +A Sbjct: 495 PYLDDLGFNLVGYGCTTCIGNSGPLLPEIEKAIADEDLLVTSVLSGNRNFEGRIHPLVKA 554 Query: 373 NYLASPPLVVAYALAGTVNIDFEKEPVGISKDGKEVYFRDIWPSTDEIAEVVKSSVLPDM 552 NYLASP LVVAYALAGTV+ID + EP+G DG++VY +DIWPS E+++ V S V P++ Sbjct: 555 NYLASPQLVVAYALAGTVDIDLQNEPIGKGNDGEDVYLKDIWPSIKEVSDTVDSVVTPEL 614 Query: 553 FKGTYEAITKGNPMWNELPVSASTLYPWDPKSTYIHEPPYFKDMTMTP 696 F Y + N +WNE+ V+ LY +DP STYI P +F+ ++ P Sbjct: 615 FIEEYNNVYNNNELWNEIDVTDQPLYDFDPNSTYIQNPSFFQGLSKEP 662
>ACON_STAAS (Q6G9K9) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 901 Score = 280 bits (716), Expect = 3e-75 Identities = 134/228 (58%), Positives = 168/228 (73%) Frame = +1 Query: 13 VVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQ 192 + IAAITSCTNTSNP VMLGA LVAKKA + GL+V ++KTSLAPGS VV YL +GLQ Sbjct: 435 IAIAAITSCTNTSNPYVMLGAGLVAKKAVEKGLKVPEYVKTSLAPGSKVVTGYLRDAGLQ 494 Query: 193 KYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRA 372 YL+ LGFN+VGYGCTTCIGNSG L + AI D D++ +VLSGNRNFEGR+H L +A Sbjct: 495 PYLDDLGFNLVGYGCTTCIGNSGPLLPEIEKAIADEDLLVTSVLSGNRNFEGRIHPLVKA 554 Query: 373 NYLASPPLVVAYALAGTVNIDFEKEPVGISKDGKEVYFRDIWPSTDEIAEVVKSSVLPDM 552 NYLASP LVVAYALAGTV+ID + EP+G DG++VY +DIWPS E+++ V S V P++ Sbjct: 555 NYLASPQLVVAYALAGTVDIDLQNEPIGKGNDGEDVYLKDIWPSIKEVSDTVDSVVTPEL 614 Query: 553 FKGTYEAITKGNPMWNELPVSASTLYPWDPKSTYIHEPPYFKDMTMTP 696 F Y + N +WNE+ V+ LY +DP STYI P +F+ ++ P Sbjct: 615 FIEEYNNVYNNNELWNEIDVTDQPLYDFDPNSTYIQNPSFFQGLSKEP 662
>ACON_STAAN (P99148) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 901 Score = 280 bits (716), Expect = 3e-75 Identities = 134/228 (58%), Positives = 168/228 (73%) Frame = +1 Query: 13 VVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQ 192 + IAAITSCTNTSNP VMLGA LVAKKA + GL+V ++KTSLAPGS VV YL +GLQ Sbjct: 435 IAIAAITSCTNTSNPYVMLGAGLVAKKAVEKGLKVPEYVKTSLAPGSKVVTGYLRDAGLQ 494 Query: 193 KYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRA 372 YL+ LGFN+VGYGCTTCIGNSG L + AI D D++ +VLSGNRNFEGR+H L +A Sbjct: 495 PYLDDLGFNLVGYGCTTCIGNSGPLLPEIEKAIADEDLLVTSVLSGNRNFEGRIHPLVKA 554 Query: 373 NYLASPPLVVAYALAGTVNIDFEKEPVGISKDGKEVYFRDIWPSTDEIAEVVKSSVLPDM 552 NYLASP LVVAYALAGTV+ID + EP+G DG++VY +DIWPS E+++ V S V P++ Sbjct: 555 NYLASPQLVVAYALAGTVDIDLQNEPIGKGNDGEDVYLKDIWPSIKEVSDTVDSVVTPEL 614 Query: 553 FKGTYEAITKGNPMWNELPVSASTLYPWDPKSTYIHEPPYFKDMTMTP 696 F Y + N +WNE+ V+ LY +DP STYI P +F+ ++ P Sbjct: 615 FIEEYNNVYNNNELWNEIDVTDQPLYDFDPNSTYIQNPSFFQGLSKEP 662
>ACON_STAAM (P63433) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 901 Score = 280 bits (716), Expect = 3e-75 Identities = 134/228 (58%), Positives = 168/228 (73%) Frame = +1 Query: 13 VVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQ 192 + IAAITSCTNTSNP VMLGA LVAKKA + GL+V ++KTSLAPGS VV YL +GLQ Sbjct: 435 IAIAAITSCTNTSNPYVMLGAGLVAKKAVEKGLKVPEYVKTSLAPGSKVVTGYLRDAGLQ 494 Query: 193 KYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRA 372 YL+ LGFN+VGYGCTTCIGNSG L + AI D D++ +VLSGNRNFEGR+H L +A Sbjct: 495 PYLDDLGFNLVGYGCTTCIGNSGPLLPEIEKAIADEDLLVTSVLSGNRNFEGRIHPLVKA 554 Query: 373 NYLASPPLVVAYALAGTVNIDFEKEPVGISKDGKEVYFRDIWPSTDEIAEVVKSSVLPDM 552 NYLASP LVVAYALAGTV+ID + EP+G DG++VY +DIWPS E+++ V S V P++ Sbjct: 555 NYLASPQLVVAYALAGTVDIDLQNEPIGKGNDGEDVYLKDIWPSIKEVSDTVDSVVTPEL 614 Query: 553 FKGTYEAITKGNPMWNELPVSASTLYPWDPKSTYIHEPPYFKDMTMTP 696 F Y + N +WNE+ V+ LY +DP STYI P +F+ ++ P Sbjct: 615 FIEEYNNVYNNNELWNEIDVTDQPLYDFDPNSTYIQNPSFFQGLSKEP 662
>ACON_STAAC (Q5HG69) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 901 Score = 280 bits (716), Expect = 3e-75 Identities = 134/228 (58%), Positives = 168/228 (73%) Frame = +1 Query: 13 VVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQ 192 + IAAITSCTNTSNP VMLGA LVAKKA + GL+V ++KTSLAPGS VV YL +GLQ Sbjct: 435 IAIAAITSCTNTSNPYVMLGAGLVAKKAVEKGLKVPEYVKTSLAPGSKVVTGYLRDAGLQ 494 Query: 193 KYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRA 372 YL+ LGFN+VGYGCTTCIGNSG L + AI D D++ +VLSGNRNFEGR+H L +A Sbjct: 495 PYLDDLGFNLVGYGCTTCIGNSGPLLPEIEKAIADEDLLVTSVLSGNRNFEGRIHPLVKA 554 Query: 373 NYLASPPLVVAYALAGTVNIDFEKEPVGISKDGKEVYFRDIWPSTDEIAEVVKSSVLPDM 552 NYLASP LVVAYALAGTV+ID + EP+G DG++VY +DIWPS E+++ V S V P++ Sbjct: 555 NYLASPQLVVAYALAGTVDIDLQNEPIGKGNDGEDVYLKDIWPSIKEVSDTVDSVVTPEL 614 Query: 553 FKGTYEAITKGNPMWNELPVSASTLYPWDPKSTYIHEPPYFKDMTMTP 696 F Y + N +WNE+ V+ LY +DP STYI P +F+ ++ P Sbjct: 615 FIEEYNNVYNNNELWNEIDVTDQPLYDFDPNSTYIQNPSFFQGLSKEP 662
>ACON_STAAR (Q6GH55) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 901 Score = 278 bits (711), Expect = 1e-74 Identities = 133/228 (58%), Positives = 168/228 (73%) Frame = +1 Query: 13 VVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQ 192 + IAAITSCTNTSNP VMLGA LVAKKA + GL+V ++KTSLAPGS VV YL +GLQ Sbjct: 435 IAIAAITSCTNTSNPYVMLGAGLVAKKAVEKGLKVPEYVKTSLAPGSKVVTGYLRGAGLQ 494 Query: 193 KYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRA 372 YL+ LGFN+VGYGCTTCIGNSG L + AI D D++ +VLSGNRNFEGR+H L +A Sbjct: 495 PYLDDLGFNLVGYGCTTCIGNSGPLLPEIEKAIADEDLLVTSVLSGNRNFEGRIHPLVKA 554 Query: 373 NYLASPPLVVAYALAGTVNIDFEKEPVGISKDGKEVYFRDIWPSTDEIAEVVKSSVLPDM 552 NYLASP LVVAYALAG+V+ID + EP+G DG++VY +DIWPS E+++ V S V P++ Sbjct: 555 NYLASPQLVVAYALAGSVDIDLQNEPIGKGNDGEDVYLKDIWPSIKEVSDTVDSVVTPEL 614 Query: 553 FKGTYEAITKGNPMWNELPVSASTLYPWDPKSTYIHEPPYFKDMTMTP 696 F Y + N +WNE+ V+ LY +DP STYI P +F+ ++ P Sbjct: 615 FIEEYNNVYNNNELWNEIDVTDQPLYDFDPNSTYIQNPSFFQGLSKEP 662
>ACON_LEGPH (P37032) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) (Major iron-containing protein) (MICP) (IP210) Length = 891 Score = 277 bits (708), Expect = 3e-74 Identities = 131/228 (57%), Positives = 170/228 (74%) Frame = +1 Query: 13 VVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQ 192 VVIAAITSCTNTSNP+V++ A LVAKKA + GL+ KPW+K+SLAPGS VV YL +GLQ Sbjct: 427 VVIAAITSCTNTSNPSVLMAAGLVAKKAIEKGLQRKPWVKSSLAPGSKVVTDYLRHAGLQ 486 Query: 193 KYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRA 372 YL+QLGFN+VGYGCTTCIGNSG L + ++ + ++D+V ++VLSGNRNFEGRVH RA Sbjct: 487 TYLDQLGFNLVGYGCTTCIGNSGPLPDDISHCVAEHDLVVSSVLSGNRNFEGRVHPQVRA 546 Query: 373 NYLASPPLVVAYALAGTVNIDFEKEPVGISKDGKEVYFRDIWPSTDEIAEVVKSSVLPDM 552 N+LASPPLVVAYAL GT D +EP+G K+G +VY +DIWPS +EIA V + V M Sbjct: 547 NWLASPPLVVAYALCGTTCSDLSREPIGQDKEGNDVYLKDIWPSNEEIAAEV-AKVSGTM 605 Query: 553 FKGTYEAITKGNPMWNELPVSASTLYPWDPKSTYIHEPPYFKDMTMTP 696 F+ Y + KG+ W + S+ Y W+P STYI PP+F+++++ P Sbjct: 606 FRKEYAEVFKGDAHWQAIQTSSGQTYEWNPDSTYIQHPPFFENLSLKP 653
>ACON_RICCN (Q92G90) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 878 Score = 275 bits (704), Expect = 7e-74 Identities = 134/224 (59%), Positives = 169/224 (75%) Frame = +1 Query: 13 VVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQ 192 VVIAAITSCTNTSNP+VM+GAAL+AKKA + GL+VKPW+KTSLAPGS VV +YL SGL Sbjct: 418 VVIAAITSCTNTSNPSVMIGAALLAKKALEHGLKVKPWVKTSLAPGSKVVTEYLKLSGLD 477 Query: 193 KYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRA 372 KYL++LGFN+VGYGCTTCIGNSG L+ + I N +V A+VLSGNRNFEGR++ LT+A Sbjct: 478 KYLDELGFNLVGYGCTTCIGNSGPLNPEIEETINKNGLVVASVLSGNRNFEGRINPLTKA 537 Query: 373 NYLASPPLVVAYALAGTVNIDFEKEPVGISKDGKEVYFRDIWPSTDEIAEVVKSSVLPDM 552 +YL SP LVVAYAL+GT+NID P+ G+ +Y +D+WPS +EI EV+ +S+ M Sbjct: 538 SYLGSPILVVAYALSGTLNIDLTNMPI-----GENIYLKDLWPSKEEIDEVIANSINSSM 592 Query: 553 FKGTYEAITKGNPMWNELPVSASTLYPWDPKSTYIHEPPYFKDM 684 F Y I G W +L V+ S+ Y W+ STYI+ PPYFKD+ Sbjct: 593 FIEKYSDIFSGTKEWKDLQVTNSSTYNWNKNSTYINNPPYFKDI 636
>ACON_RICPR (Q9ZCF4) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 878 Score = 271 bits (693), Expect = 1e-72 Identities = 133/224 (59%), Positives = 165/224 (73%) Frame = +1 Query: 13 VVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQ 192 VVIAAITSCTNTSNP+VM+GAAL+AKKA + GL VKPW+KTSLAPGS VV +YL SGL Sbjct: 418 VVIAAITSCTNTSNPSVMIGAALLAKKALEHGLNVKPWVKTSLAPGSKVVTEYLKLSGLD 477 Query: 193 KYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRA 372 KYL+ LGFN+VGYGCTTCIGNSG L+ + I N +V A+VLSGNRNFEGR++ LT+A Sbjct: 478 KYLDALGFNLVGYGCTTCIGNSGSLNPEIENTINKNRLVVASVLSGNRNFEGRINPLTKA 537 Query: 373 NYLASPPLVVAYALAGTVNIDFEKEPVGISKDGKEVYFRDIWPSTDEIAEVVKSSVLPDM 552 +YLASP LVVAYAL+GT+NID P+G + +Y +DIWPS EI EV+ +S+ M Sbjct: 538 SYLASPILVVAYALSGTLNIDLTNTPIGAN-----IYLKDIWPSQKEIDEVIANSINSSM 592 Query: 553 FKGTYEAITKGNPMWNELPVSASTLYPWDPKSTYIHEPPYFKDM 684 F Y + G W +L ++ T Y WD STYI+ PPYF ++ Sbjct: 593 FIEKYADVFNGTKEWRDLQITTGTNYNWDKNSTYINNPPYFDNI 636
>IREB2_RAT (Q62751) Iron-responsive element-binding protein 2 (IRE-BP 2) (Iron| regulatory protein 2) (IRP2) Length = 963 Score = 270 bits (689), Expect = 4e-72 Identities = 127/228 (55%), Positives = 161/228 (70%) Frame = +1 Query: 13 VVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQ 192 VVIAA+ SCTN NP+VML A L+AKKA + GL VKP+I+TSL+PGSG+V YL SG+ Sbjct: 504 VVIAAVISCTNNCNPSVMLAAGLLAKKAVETGLRVKPYIRTSLSPGSGMVTHYLSSSGVL 563 Query: 193 KYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRA 372 YL++LGF IVGYGC+TC+GN+ L E++ A+ D+V VLSGN+NFEGR+ RA Sbjct: 564 PYLSKLGFEIVGYGCSTCVGNTAPLSEAILNAVKQGDLVTCGVLSGNKNFEGRLCDCVRA 623 Query: 373 NYLASPPLVVAYALAGTVNIDFEKEPVGISKDGKEVYFRDIWPSTDEIAEVVKSSVLPDM 552 NYLASPPLVVAYA+AGTVNIDF+ EP+G GK +Y DIWPS +E+ ++ + V+ M Sbjct: 624 NYLASPPLVVAYAIAGTVNIDFQTEPLGTDSTGKNIYLHDIWPSREEVHQIEEEHVILSM 683 Query: 553 FKGTYEAITKGNPMWNELPVSASTLYPWDPKSTYIHEPPYFKDMTMTP 696 FK E + GN WN L S L+PWD KSTYI P +F +T P Sbjct: 684 FKALKEKVEMGNKRWNSLDAPDSVLFPWDVKSTYIRCPSFFDKLTKEP 731
>IREB2_MOUSE (Q811J3) Iron-responsive element-binding protein 2 (IRE-BP 2) (Iron| regulatory protein 2) (IRP2) Length = 963 Score = 270 bits (689), Expect = 4e-72 Identities = 128/228 (56%), Positives = 164/228 (71%) Frame = +1 Query: 13 VVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQ 192 VVIAA+ SCTN NP+VML A L+AKKA ++GL VKP+I+TSL+PGSG+V YL SG+ Sbjct: 504 VVIAAVISCTNNCNPSVMLAAGLLAKKAVEIGLRVKPYIRTSLSPGSGMVTHYLSSSGVL 563 Query: 193 KYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRA 372 YL++LGF+IVGYGC+TC+GN+ L E+V A+ D+V VLSGN++FEGR+ RA Sbjct: 564 PYLSKLGFDIVGYGCSTCVGNTAPLSEAVLNAVKQGDLVTCGVLSGNKHFEGRLCDCDRA 623 Query: 373 NYLASPPLVVAYALAGTVNIDFEKEPVGISKDGKEVYFRDIWPSTDEIAEVVKSSVLPDM 552 NYLASPPLVVAYA+AGTVNIDF+ EP+G GKE+Y DIWPS +E+ ++ + V+ M Sbjct: 624 NYLASPPLVVAYAIAGTVNIDFQTEPLGTDSTGKEIYLHDIWPSREEVHQMEEEHVILSM 683 Query: 553 FKGTYEAITKGNPMWNELPVSASTLYPWDPKSTYIHEPPYFKDMTMTP 696 FK E + GN WN L S L+PWD KSTYI P +F +T P Sbjct: 684 FKTLKEKVEMGNKRWNSLEAPDSVLFPWDVKSTYIRCPSFFDKLTKEP 731
>ACON_BRAJA (P70920) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 906 Score = 269 bits (688), Expect = 5e-72 Identities = 131/228 (57%), Positives = 165/228 (72%) Frame = +1 Query: 13 VVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQ 192 VVIAAITSCTNTSNP+V++GA L+A+ A GL+ KPW+KTSLAPGS VV YL SGLQ Sbjct: 435 VVIAAITSCTNTSNPSVLIGAGLLARNAAAKGLKAKPWVKTSLAPGSQVVAAYLADSGLQ 494 Query: 193 KYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRA 372 +L+++GFN+VG+GCTTCIGNSG L E ++ +I DN +VAAAVLSGNRNFEGRV +A Sbjct: 495 AHLDKVGFNLVGFGCTTCIGNSGPLPEEISKSINDNGIVAAAVLSGNRNFEGRVSPDVQA 554 Query: 373 NYLASPPLVVAYALAGTVNIDFEKEPVGISKDGKEVYFRDIWPSTDEIAEVVKSSVLPDM 552 NYLASPPLVVA+ALAG+V + EP+G KDGK VY +DIWP++ EI +K V + Sbjct: 555 NYLASPPLVVAHALAGSVTKNLAVEPLGEGKDGKPVYLKDIWPTSKEINAFMKKFVTASI 614 Query: 553 FKGTYEAITKGNPMWNELPVSASTLYPWDPKSTYIHEPPYFKDMTMTP 696 FK Y + KG+ W ++ S Y W+ STY+ PPYF+ M P Sbjct: 615 FKKKYADVFKGDTNWRKIKTVESETYRWNMSSTYVQNPPYFEGMKKEP 662
>ACOC_CAEEL (Q23500) Probable aconitate hydratase, cytoplasmic (EC 4.2.1.3)| (Citrate hydro-lyase) (Aconitase) Length = 887 Score = 269 bits (687), Expect = 7e-72 Identities = 133/229 (58%), Positives = 162/229 (70%) Frame = +1 Query: 13 VVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQ 192 VVIAAITSCTNTSNP+VML A LVAKKA +LGL V+P++KTSL+PGSGVV KYL+ SGL Sbjct: 428 VVIAAITSCTNTSNPSVMLAAGLVAKKAVELGLNVQPYVKTSLSPGSGVVTKYLEASGLL 487 Query: 193 KYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRA 372 YL ++GFNI GYGC TCIGNSG LDE V AI +N++V A VLSGNRNFEGR+H RA Sbjct: 488 PYLEKIGFNIAGYGCMTCIGNSGPLDEPVTKAIEENNLVVAGVLSGNRNFEGRIHPHVRA 547 Query: 373 NYLASPPLVVAYALAGTVNIDFEKEPVGISKDGKEVYFRDIWPSTDEIAEVVKSSVLPDM 552 NYLASPPL V Y++ G VN+D + ++ DGKE+ DIWP+ E+A+ + V P Sbjct: 548 NYLASPPLAVLYSIIGNVNVDI-NGVLAVTPDGKEIRLADIWPTRKEVAKFEEEFVKPQF 606 Query: 553 FKGTYEAITKGNPMWNELPVSASTLYPWDPKSTYIHEPPYFKDMTMTPP 699 F+ Y I G+ W +L A LYPWD STYI + P+F MT P Sbjct: 607 FREVYANIELGSTEWQQLECPAVKLYPWDDASTYIKKVPFFDGMTSELP 655
>ACON_CORJK (Q4JVM4) Aconitate hydratase (EC 4.2.1.3)| Length = 936 Score = 268 bits (686), Expect = 9e-72 Identities = 124/228 (54%), Positives = 166/228 (72%) Frame = +1 Query: 13 VVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQ 192 V IA+ITSCTNTSNP+VM+GA L+A+ A GL+ PW+KTS+APGS VV Y +K+GL Sbjct: 464 VAIASITSCTNTSNPSVMVGAGLLARNAAAKGLKSAPWVKTSMAPGSQVVNGYYEKAGLW 523 Query: 193 KYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRA 372 K L +GF +VGYGCTTCIGNSG L E ++A I + D+ A AVLSGNRNFEGR++ + Sbjct: 524 KDLEAMGFYLVGYGCTTCIGNSGPLPEEISAGINEGDLAATAVLSGNRNFEGRINPDVKM 583 Query: 373 NYLASPPLVVAYALAGTVNIDFEKEPVGISKDGKEVYFRDIWPSTDEIAEVVKSSVLPDM 552 NYLASP LV+AYA+AGT++ DFE +P+G +DG +V+ +DIWPST++I EV+ SS+ D+ Sbjct: 584 NYLASPILVIAYAIAGTMDFDFETQPLGQDQDGNDVFLKDIWPSTEDIEEVIASSITKDL 643 Query: 553 FKGTYEAITKGNPMWNELPVSASTLYPWDPKSTYIHEPPYFKDMTMTP 696 + Y + +G+ W L V + + WDPKSTYI + PYF M+ P Sbjct: 644 YAEDYANVFEGDERWRSLDVPSGKTFDWDPKSTYIRKAPYFDGMSKEP 691
>IREB2_HUMAN (P48200) Iron-responsive element-binding protein 2 (IRE-BP 2) (Iron| regulatory protein 2) (IRP2) Length = 963 Score = 266 bits (681), Expect = 3e-71 Identities = 127/228 (55%), Positives = 160/228 (70%) Frame = +1 Query: 13 VVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQ 192 VVIAA+ SCTN NP+VML A L+AKKA + GL VKP+I+TSL+PGSG+V YL SG+ Sbjct: 504 VVIAAVISCTNNCNPSVMLAAGLLAKKAVEAGLRVKPYIRTSLSPGSGMVTHYLSSSGVL 563 Query: 193 KYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRA 372 YL++LGF IVGYGC+TC+GN+ L ++V A+ D+V +LSGN+NFEGR+ RA Sbjct: 564 PYLSKLGFEIVGYGCSTCVGNTAPLSDAVLNAVKQGDLVTCGILSGNKNFEGRLCDCVRA 623 Query: 373 NYLASPPLVVAYALAGTVNIDFEKEPVGISKDGKEVYFRDIWPSTDEIAEVVKSSVLPDM 552 NYLASPPLVVAYA+AGTVNIDF+ EP+G GK +Y DIWPS +E+ V + V+ M Sbjct: 624 NYLASPPLVVAYAIAGTVNIDFQTEPLGTDPTGKNIYLHDIWPSREEVHRVEEEHVILSM 683 Query: 553 FKGTYEAITKGNPMWNELPVSASTLYPWDPKSTYIHEPPYFKDMTMTP 696 FK + I GN WN L S L+PWD KSTYI P +F +T P Sbjct: 684 FKALKDKIEMGNKRWNSLEAPDSVLFPWDLKSTYIRCPSFFDKLTKEP 731
>ACON_STRMU (Q59938) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 888 Score = 264 bits (675), Expect = 2e-70 Identities = 129/227 (56%), Positives = 164/227 (72%) Frame = +1 Query: 13 VVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQ 192 V IAAITSCTNTSNP V+L A L+AKKA + GL V +KTSLAPGS VV YL KSGLQ Sbjct: 425 VAIAAITSCTNTSNPYVLLSAGLLAKKAVERGLSVAKTVKTSLAPGSKVVTAYLRKSGLQ 484 Query: 193 KYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRA 372 YL++LGFN+VGYGCTTCIGNSGDL VA A+ + D++ +AVLSGNRNFEGRV+ L +A Sbjct: 485 PYLDKLGFNLVGYGCTTCIGNSGDLVPEVAKAVQEKDLLVSAVLSGNRNFEGRVNPLVKA 544 Query: 373 NYLASPPLVVAYALAGTVNIDFEKEPVGISKDGKEVYFRDIWPSTDEIAEVVKSSVLPDM 552 N+LASPPLVVAYALAGT NID +P+G K+G+ VY DI P+ +E+ ++ V ++ Sbjct: 545 NFLASPPLVVAYALAGTTNIDLTSKPLGYDKNGQAVYLEDIMPAKEEVLSYIEQFVTAEL 604 Query: 553 FKGTYEAITKGNPMWNELPVSASTLYPWDPKSTYIHEPPYFKDMTMT 693 F+ Y + + WN++ S Y W+ STYI PPYF+++T T Sbjct: 605 FEEEYGHVFSDSQKWNQIETENSKNYQWNQVSTYIQNPPYFENLTNT 651
>ACON_CORDI (Q6NH63) Aconitate hydratase (EC 4.2.1.3)| Length = 934 Score = 261 bits (668), Expect = 1e-69 Identities = 121/228 (53%), Positives = 160/228 (70%) Frame = +1 Query: 13 VVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQ 192 V IA+ITSCTNTSNP+VM+GA L+A+KA GL+ KPW+KT APGS VV Y ++ L Sbjct: 465 VAIASITSCTNTSNPSVMIGAGLIARKAAAKGLKAKPWVKTICAPGSQVVDGYYKRADLW 524 Query: 193 KYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRA 372 K L LGF + G+GCTTCIGNSG L E ++AAI +ND+ A AVLSGNRNFEGR+ + Sbjct: 525 KDLEALGFYLSGFGCTTCIGNSGPLPEEISAAINENDLTATAVLSGNRNFEGRISPDVKM 584 Query: 373 NYLASPPLVVAYALAGTVNIDFEKEPVGISKDGKEVYFRDIWPSTDEIAEVVKSSVLPDM 552 NYL SP +V+AYA+AGT++ DFE +P+G DG +V+ +DIWPST+EI E + ++ ++ Sbjct: 585 NYLVSPIMVIAYAIAGTMDFDFETQPLGQDIDGNDVFLKDIWPSTEEIEETIAGAISREL 644 Query: 553 FKGTYEAITKGNPMWNELPVSASTLYPWDPKSTYIHEPPYFKDMTMTP 696 ++ Y + KG+ W LP + WD KSTYI + PYF MTM P Sbjct: 645 YEADYADVFKGDEQWQNLPTPEGKTFDWDEKSTYIRKAPYFDGMTMEP 692
>ACON1_ECOLI (P25516) Aconitate hydratase 1 (EC 4.2.1.3) (Citrate hydro-lyase 1)| (Aconitase 1) Length = 890 Score = 261 bits (667), Expect = 1e-69 Identities = 128/228 (56%), Positives = 159/228 (69%) Frame = +1 Query: 13 VVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQ 192 VVIAAITSCTNTSNP+V++ A L+AKKA LGL+ +PW+K SLAPGS VV YL K+ L Sbjct: 426 VVIAAITSCTNTSNPSVLMAAGLLAKKAVTLGLKRQPWVKASLAPGSKVVSDYLAKAKLT 485 Query: 193 KYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRA 372 YL++LGFN+VGYGCTTCIGNSG L + + AI D+ AVLSGNRNFEGR+H L + Sbjct: 486 PYLDELGFNLVGYGCTTCIGNSGPLPDPIETAIKKGDLTVGAVLSGNRNFEGRIHPLVKT 545 Query: 373 NYLASPPLVVAYALAGTVNIDFEKEPVGISKDGKEVYFRDIWPSTDEIAEVVKSSVLPDM 552 N+LASPPLVVAYALAG +NI+ EP+G + G VY +DIWPS EIA V+ V +M Sbjct: 546 NWLASPPLVVAYALAGNMNINLASEPIGHDRKGDPVYLKDIWPSAQEIARAVE-QVSTEM 604 Query: 553 FKGTYEAITKGNPMWNELPVSASTLYPWDPKSTYIHEPPYFKDMTMTP 696 F+ Y + +G W + V+ S Y W STYI P+F +M TP Sbjct: 605 FRKEYAEVFEGTAEWKGINVTRSDTYGWQEDSTYIRLSPFFDEMQATP 652
>ACON_COREF (Q8FTA8) Aconitate hydratase (EC 4.2.1.3)| Length = 937 Score = 258 bits (659), Expect = 1e-68 Identities = 118/228 (51%), Positives = 163/228 (71%) Frame = +1 Query: 13 VVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQ 192 V IA+ITSCTNTSNP+VM+GA L+A+KA + GL+ KPW+KT APGS VV Y ++ L Sbjct: 467 VAIASITSCTNTSNPSVMIGAGLIARKAAEKGLKSKPWVKTICAPGSQVVDGYYQRADLW 526 Query: 193 KYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRA 372 K L LGF + G+GCTTCIGNSG L E ++ AI ++D+ A AVLSGNRNFEGR+ + Sbjct: 527 KDLEALGFYLSGFGCTTCIGNSGPLPEEISEAINEHDLAATAVLSGNRNFEGRISPDVKM 586 Query: 373 NYLASPPLVVAYALAGTVNIDFEKEPVGISKDGKEVYFRDIWPSTDEIAEVVKSSVLPDM 552 NYLASP +V+AYA+AGT++ DFE E +G +DG +V+ +DIWPST+EI E +++++ ++ Sbjct: 587 NYLASPIMVIAYAIAGTMDFDFENEALGQDQDGNDVFLKDIWPSTEEIEETIQAAISREL 646 Query: 553 FKGTYEAITKGNPMWNELPVSASTLYPWDPKSTYIHEPPYFKDMTMTP 696 ++ Y + KG+ W EL + + + WD STYI + PYF MT P Sbjct: 647 YEADYADVFKGDKQWQELDIPSGKTFEWDENSTYIRKAPYFDGMTAEP 694
>ACON_CORGL (Q8NQ98) Aconitate hydratase (EC 4.2.1.3)| Length = 939 Score = 256 bits (654), Expect = 5e-68 Identities = 117/228 (51%), Positives = 162/228 (71%) Frame = +1 Query: 13 VVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQ 192 V IA+ITSCTNTSNP+VM+GA L+A+KA + GL+ KPW+KT APGS VV Y ++ L Sbjct: 467 VAIASITSCTNTSNPSVMIGAGLIARKAAEKGLKSKPWVKTICAPGSQVVDGYYQRADLW 526 Query: 193 KYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRA 372 K L +GF + G+GCTTCIGNSG L E ++AAI ++D+ A AVLSGNRNFEGR+ + Sbjct: 527 KDLEAMGFYLSGFGCTTCIGNSGPLPEEISAAINEHDLTATAVLSGNRNFEGRISPDVKM 586 Query: 373 NYLASPPLVVAYALAGTVNIDFEKEPVGISKDGKEVYFRDIWPSTDEIAEVVKSSVLPDM 552 NYLASP +V+AYA+AGT++ DFE E +G +DG +V+ +DIWPST+EI + ++ ++ ++ Sbjct: 587 NYLASPIMVIAYAIAGTMDFDFENEALGQDQDGNDVFLKDIWPSTEEIEDTIQQAISREL 646 Query: 553 FKGTYEAITKGNPMWNELPVSASTLYPWDPKSTYIHEPPYFKDMTMTP 696 ++ Y + KG+ W EL V + WD STYI + PYF M + P Sbjct: 647 YEADYADVFKGDKQWQELDVPTGDTFEWDENSTYIRKAPYFDGMPVEP 694
>ACON_FRATH (Q2A1K3) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 937 Score = 249 bits (637), Expect = 4e-66 Identities = 124/222 (55%), Positives = 158/222 (71%) Frame = +1 Query: 13 VVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQ 192 V IAAITSCTNTSNP+++LGA L+AKKA + GL+VKP++KTSLAPGS VV +YL+K+ L Sbjct: 431 VAIAAITSCTNTSNPSLLLGAGLLAKKANEKGLKVKPFVKTSLAPGSQVVTQYLEKANLL 490 Query: 193 KYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRA 372 L LGFN+VGYGCTTCIGNSG LDE V AI + D++ A+V SGNRNFEGR++ +A Sbjct: 491 PELENLGFNLVGYGCTTCIGNSGPLDEPVVEAINEADLIVASVSSGNRNFEGRINPHIKA 550 Query: 373 NYLASPPLVVAYALAGTVNIDFEKEPVGISKDGKEVYFRDIWPSTDEIAEVVKSSVLPDM 552 NYLASP VVAYALAGTV+ D ++ +G +G +VY DIWP+T+EIA + + DM Sbjct: 551 NYLASPIHVVAYALAGTVDFDPVEDAIGKDAEGNDVYLADIWPTTEEIAAIQSHVINSDM 610 Query: 553 FKGTYEAITKGNPMWNELPVSASTLYPWDPKSTYIHEPPYFK 678 FK Y + G W +L LY +D STYI P +F+ Sbjct: 611 FKKAYATVLDGTEEWQKLKAPEGKLYEFDSSSTYIQCPNFFE 652
>ACON_MYCAV (O08451) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 961 Score = 245 bits (626), Expect = 8e-65 Identities = 124/230 (53%), Positives = 155/230 (67%), Gaps = 2/230 (0%) Frame = +1 Query: 13 VVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQ 192 VVIAA+TSCTNTSNP VMLGAAL+A++ + GL KPW+KT++APGS VV Y DK+GL Sbjct: 491 VVIAAVTSCTNTSNPEVMLGAALLARQRVEKGLASKPWVKTTMAPGSQVVHDYYDKAGLW 550 Query: 193 KYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRA 372 YL +LGF +VGYGCTTCIGNSG L E ++ AI DND+ AVLSGNRNFEGR++ + Sbjct: 551 PYLEKLGFYLVGYGCTTCIGNSGPLPEEISKAINDNDLSVTAVLSGNRNFEGRINPDVKM 610 Query: 373 NYLASPPLVVAYALAGTVNIDFEKEPVGISKDGKEVYFRDIWPSTDEIAE--VVKSSVLP 546 NY ASPPLVVAYALAGT+ EK+P+G KDG +VY +DI S + + +S Sbjct: 611 NYPASPPLVVAYALAGTMT-RLEKQPLGKDKDGNDVYLKDICRSQKTLGHHPIGDNS--- 666 Query: 547 DMFKGTYEAITKGNPMWNELPVSASTLYPWDPKSTYIHEPPYFKDMTMTP 696 + F Y + KG W LP + W P STY+ +PPYF+ M P Sbjct: 667 EWFTKNYADVFKGEQAWRNLPTPTRNTFEWSPDSTYVRKPPYFEGMPAEP 716
>LEU2_RHINI (P55811) 3-isopropylmalate dehydratase (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 750 Score = 68.6 bits (166), Expect = 2e-11 Identities = 57/197 (28%), Positives = 83/197 (42%), Gaps = 1/197 (0%) Frame = +1 Query: 4 GTRVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKS 183 G ++ I SCTN+ ++ AA+V G V W+ + PGS +VK+ ++ Sbjct: 342 GVKIDKVFIGSCTNSRIEDLGPAAAIVK------GKRVADWVDAMVVPGSALVKRQAERK 395 Query: 184 GLQKYLNQLGFNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHA 360 GL K + GFN GC+ C+G N L A T NRNF+GR A Sbjct: 396 GLDKIFQEAGFNWREAGCSMCLGMNPDQLKPGERCAST-----------SNRNFKGRQGA 444 Query: 361 LTRANYLASPPLVVAYALAGTVNIDFEKEPVGISKDGKEVYFRDIWPSTDEIAEVVKSSV 540 R +L SP + A + G + E GI+ G E P + +A S Sbjct: 445 GGR-THLLSPAMAAAAGIKGCLTDVRHMEVAGIALTGNES------PRQEVVASKYDGS- 496 Query: 541 LPDMFKGTYEAITKGNP 591 P++FK T + P Sbjct: 497 -PEVFKSTQDTTPAVKP 512
>ACON_HUMAN (Q99798) Aconitate hydratase, mitochondrial precursor (EC 4.2.1.3)| (Citrate hydro-lyase) (Aconitase) Length = 780 Score = 63.2 bits (152), Expect = 8e-10 Identities = 54/167 (32%), Positives = 82/167 (49%), Gaps = 1/167 (0%) Frame = +1 Query: 19 IAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKY 198 + I SCTN+S ++ AA VAK+A GL+ K + ++ PGS ++ +++ G + Sbjct: 379 VGLIGSCTNSSYEDMGRSAA-VAKQALAHGLKCKS--QFTITPGSEQIRATIERDGYAQI 435 Query: 199 LNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRAN- 375 L LG ++ C CIG D T V S NRNF GR A + Sbjct: 436 LRDLGGIVLANACGPCIGQWDRKDIKKGEKNT-------IVTSYNRNFTGRNDANPETHA 488 Query: 376 YLASPPLVVAYALAGTVNIDFEKEPVGISKDGKEVYFRDIWPSTDEI 516 ++ SP +V A A+AGT+ + E + + DGK+ FR P DE+ Sbjct: 489 FVTSPEIVTALAIAGTLKFNPETDYL-TGTDGKK--FRLEAPDADEL 532
>ACON_BOVIN (P20004) Aconitate hydratase, mitochondrial precursor (EC 4.2.1.3)| (Citrate hydro-lyase) (Aconitase) Length = 780 Score = 63.2 bits (152), Expect = 8e-10 Identities = 53/167 (31%), Positives = 83/167 (49%), Gaps = 1/167 (0%) Frame = +1 Query: 19 IAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKY 198 + I SCTN+S ++ AA VAK+A GL+ K + ++ PGS ++ +++ G + Sbjct: 379 VGLIGSCTNSSYEDMGRSAA-VAKQALAHGLQCKS--QFTITPGSEQIRATIERDGYAQI 435 Query: 199 LNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRAN- 375 L +G ++ C CIG D T V S NRNF GR A + Sbjct: 436 LRDVGGIVLANACGPCIGQWDRKDIKKGEKNT-------IVTSYNRNFTGRNDANPETHA 488 Query: 376 YLASPPLVVAYALAGTVNIDFEKEPVGISKDGKEVYFRDIWPSTDEI 516 ++ SP +V A A+AGT+ + E + + KDGK+ F+ P DE+ Sbjct: 489 FVTSPEIVTALAIAGTLKFNPETDFL-TGKDGKK--FKLEAPDADEL 532
>LEU2_PHYBL (P18250) 3-isopropylmalate dehydratase (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 744 Score = 62.8 bits (151), Expect = 1e-09 Identities = 44/134 (32%), Positives = 62/134 (46%), Gaps = 1/134 (0%) Frame = +1 Query: 22 AAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYL 201 A I SCTN+ ++ A++V G + W+ + PGSG+VK+ ++ GL K Sbjct: 336 AFIGSCTNSRIEDLRSAASIVK------GKHIADWVYAMVVPGSGLVKRQAEREGLDKVF 389 Query: 202 NQLGFNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANY 378 GF+ GC+ C+G N L A T NRNFEGR A R + Sbjct: 390 TDAGFDWREAGCSMCLGMNPDQLSPGERCAST-----------SNRNFEGRQGAGGR-TH 437 Query: 379 LASPPLVVAYALAG 420 L SP + A A+ G Sbjct: 438 LMSPAMAAAAAIRG 451
>ACON_PIG (P16276) Aconitate hydratase, mitochondrial precursor (EC 4.2.1.3)| (Citrate hydro-lyase) (Aconitase) Length = 781 Score = 62.8 bits (151), Expect = 1e-09 Identities = 53/167 (31%), Positives = 83/167 (49%), Gaps = 1/167 (0%) Frame = +1 Query: 19 IAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKY 198 + I SCTN+S ++ AA VAK+A GL+ K + ++ PGS ++ +++ G + Sbjct: 379 VGLIGSCTNSSYEDMGRSAA-VAKQALAHGLKCKS--QFTITPGSEQIRATIERDGYAQV 435 Query: 199 LNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRAN- 375 L +G ++ C CIG D T V S NRNF GR A + Sbjct: 436 LRDVGGIVLANACGPCIGQWDRKDIKKGEKNT-------IVTSYNRNFTGRNDANPETHA 488 Query: 376 YLASPPLVVAYALAGTVNIDFEKEPVGISKDGKEVYFRDIWPSTDEI 516 ++ SP +V A A+AGT+ + E + + KDGK+ F+ P DE+ Sbjct: 489 FVTSPEIVTALAIAGTLKFNPETDFL-TGKDGKK--FKLEAPDADEL 532
>ACON_RAT (Q9ER34) Aconitate hydratase, mitochondrial precursor (EC 4.2.1.3)| (Citrate hydro-lyase) (Aconitase) Length = 780 Score = 62.8 bits (151), Expect = 1e-09 Identities = 53/167 (31%), Positives = 83/167 (49%), Gaps = 1/167 (0%) Frame = +1 Query: 19 IAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKY 198 + I SCTN+S ++ AA VAK+A GL+ K + ++ PGS ++ +++ G + Sbjct: 379 VGLIGSCTNSSYEDMGRSAA-VAKQALAHGLKCKS--QFTITPGSEQIRATIERDGYAQI 435 Query: 199 LNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRAN- 375 L +G ++ C CIG D T V S NRNF GR A + Sbjct: 436 LRDVGGIVLANACGPCIGQWDRKDIKKGEKNT-------IVTSYNRNFTGRNDANPETHA 488 Query: 376 YLASPPLVVAYALAGTVNIDFEKEPVGISKDGKEVYFRDIWPSTDEI 516 ++ SP +V A A+AGT+ + E + + KDGK+ F+ P DE+ Sbjct: 489 FVTSPEIVTALAIAGTLKFNPETDFL-TGKDGKK--FKLEAPDADEL 532
>ACON_MOUSE (Q99KI0) Aconitate hydratase, mitochondrial precursor (EC 4.2.1.3)| (Citrate hydro-lyase) (Aconitase) Length = 780 Score = 62.8 bits (151), Expect = 1e-09 Identities = 53/167 (31%), Positives = 83/167 (49%), Gaps = 1/167 (0%) Frame = +1 Query: 19 IAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKY 198 + I SCTN+S ++ AA VAK+A GL+ K + ++ PGS ++ +++ G + Sbjct: 379 VGLIGSCTNSSYEDMGRSAA-VAKQALAHGLKCKS--QFTITPGSEQIRATIERDGYAQI 435 Query: 199 LNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRAN- 375 L +G ++ C CIG D T V S NRNF GR A + Sbjct: 436 LRDVGGIVLANACGPCIGQWDRKDIKKGEKNT-------IVTSYNRNFTGRNDANPETHA 488 Query: 376 YLASPPLVVAYALAGTVNIDFEKEPVGISKDGKEVYFRDIWPSTDEI 516 ++ SP +V A A+AGT+ + E + + KDGK+ F+ P DE+ Sbjct: 489 FVTSPEIVTALAIAGTLKFNPETDFL-TGKDGKK--FKLEAPDADEL 532
>LEU2_RHIPU (P55251) 3-isopropylmalate dehydratase (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 755 Score = 62.8 bits (151), Expect = 1e-09 Identities = 47/132 (35%), Positives = 62/132 (46%), Gaps = 1/132 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN S + AA +AK G V W+ + PGSG+VKK ++ GL + + Sbjct: 350 IGSCTN-SRIEDLRAAAAIAK-----GRHVADWVYAMVVPGSGLVKKQAEQEGLDRIFKE 403 Query: 208 LGFNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 GF+ GC+ C+G N L A T NRNFEGR A R +L Sbjct: 404 AGFDWREAGCSMCLGMNPDQLKPGERCAST-----------SNRNFEGRQGAGGR-THLM 451 Query: 385 SPPLVVAYALAG 420 SP + A A+ G Sbjct: 452 SPAMAAAAAVTG 463
>LEU2_RHIRA (P17279) 3-isopropylmalate dehydratase (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 644 Score = 62.4 bits (150), Expect = 1e-09 Identities = 45/140 (32%), Positives = 62/140 (44%), Gaps = 1/140 (0%) Frame = +1 Query: 4 GTRVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKS 183 G +V I SCTN+ ++ AA+V G W+ + PGSG+VK+ ++ Sbjct: 389 GVKVDKVFIGSCTNSRIEDLRAAAAVVK------GKRAAEWVDAMVVPGSGLVKRQAERE 442 Query: 184 GLQKYLNQLGFNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHA 360 GL K GF+ GC+ C+G N L A T NRNFEGR A Sbjct: 443 GLDKIFTDAGFDWREAGCSMCLGMNPDQLKPGERCAST-----------SNRNFEGRQGA 491 Query: 361 LTRANYLASPPLVVAYALAG 420 R +L SP + A + G Sbjct: 492 GGR-THLVSPAMAAAAGIKG 510
>LEU2_YEAST (P07264) 3-isopropylmalate dehydratase (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 779 Score = 62.0 bits (149), Expect = 2e-09 Identities = 45/132 (34%), Positives = 64/132 (48%), Gaps = 1/132 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLA-PGSGVVKKYLDKSGLQKYLN 204 I SCTN ++ AA+V G ++ IK ++ PGSG+VKK + GL K Sbjct: 357 IGSCTNGRIEDLRSAAAVVR------GQKLASNIKLAMVVPGSGLVKKQAEAEGLDKIFQ 410 Query: 205 QLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 + GF GC+ C+G + D+ D + NRNFEGR AL+R +L Sbjct: 411 EAGFEWREAGCSICLGMNPDI----------LDAYERCASTSNRNFEGRQGALSR-THLM 459 Query: 385 SPPLVVAYALAG 420 SP + A +AG Sbjct: 460 SPAMAAAAGIAG 471
>LEU2_SYNEL (Q8DKF0) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 61.2 bits (147), Expect = 3e-09 Identities = 44/141 (31%), Positives = 65/141 (46%) Frame = +1 Query: 4 GTRVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKS 183 GT++ + I SCTN ++ A +V G +VKP +K + PGS VK + Sbjct: 338 GTKIDVCFIGSCTNGRISDLRQAAKVVE------GRKVKPGVKAFVVPGSERVKAQAEAE 391 Query: 184 GLQKYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHAL 363 GL GF GC+ C+ + D + + A+ S NRNF+GR + Sbjct: 392 GLDVVFKAAGFEWRNPGCSMCLAMNPD-------KLQGRQISAS---SSNRNFKGRQGSP 441 Query: 364 TRANYLASPPLVVAYALAGTV 426 + L SP +V A A+AG V Sbjct: 442 SGRTLLMSPAMVAAAAIAGEV 462
>LEU2_GLOVI (Q7NFV7) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 473 Score = 60.8 bits (146), Expect = 4e-09 Identities = 44/141 (31%), Positives = 65/141 (46%) Frame = +1 Query: 4 GTRVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKS 183 GT+V + I SCTN ++ A L G V P +K + PGS VK+ + Sbjct: 338 GTKVDVCFIGSCTNGRLSDLREAANLAR------GRHVAPGVKAFVVPGSERVKRQAEAE 391 Query: 184 GLQKYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHAL 363 GL + + GF GC+ C+ + D E + + S NRNF+GR + Sbjct: 392 GLHEVFLEAGFEWREPGCSMCLAMNPDRLEGRQLSAS----------SSNRNFKGRQGSA 441 Query: 364 TRANYLASPPLVVAYALAGTV 426 + L SP +VVA A++G V Sbjct: 442 SGRTLLMSPAMVVAAAVSGAV 462
>ACON_CAEEL (P34455) Probable aconitate hydratase, mitochondrial precursor (EC| 4.2.1.3) (Citrate hydro-lyase) (Aconitase) Length = 777 Score = 60.1 bits (144), Expect = 6e-09 Identities = 45/142 (31%), Positives = 69/142 (48%), Gaps = 1/142 (0%) Frame = +1 Query: 13 VVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQ 192 V ++ I SCTN+S + M AA +AK+A D GL+ K ++ PGS V+ +++ GL Sbjct: 374 VKVSLIGSCTNSSYED-MTRAASIAKQALDKGLKAKTIF--TITPGSEQVRATIERDGLS 430 Query: 193 KYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRA 372 K G ++ C CIG D T V S NRNF GR A Sbjct: 431 KIFADFGGMVLANACGPCIGQWDRQDVKKGEKNT-------IVTSYNRNFTGRNDANPAT 483 Query: 373 N-YLASPPLVVAYALAGTVNID 435 + ++ SP + A A++G ++ + Sbjct: 484 HGFVTSPDITTAMAISGRLDFN 505
>LEU2_CAUCR (Q9ABN0) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 479 Score = 60.1 bits (144), Expect = 6e-09 Identities = 45/131 (34%), Positives = 64/131 (48%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN S M AA V ++A G V P +K + PGSG+VK+ ++ GL Sbjct: 347 IGSCTN-SRIEDMRAAAAVVQEAFLHGRLVAPHVKAMVVPGSGLVKEQAEEEGLDAIFKA 405 Query: 208 LGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLAS 387 GF+ GC+ C+ + D + + A+ + NRNFEGR R +L S Sbjct: 406 AGFDWREPGCSMCLAMNPD-------KLAPQERCAS---TSNRNFEGRQGRAGR-THLVS 454 Query: 388 PPLVVAYALAG 420 P + A A+AG Sbjct: 455 PAMAAAAAIAG 465
>LEU2_CANMA (Q00464) 3-isopropylmalate dehydratase (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 770 Score = 59.7 bits (143), Expect = 8e-09 Identities = 47/136 (34%), Positives = 65/136 (47%), Gaps = 3/136 (2%) Frame = +1 Query: 22 AAITSCTNTSNPNVMLGAALVA--KKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQK 195 A I SCTN+ ++ A + KKA ++ L + + PGSG++KK +K GL K Sbjct: 349 AFIGSCTNSRIEDLRAAAKVAKGHKKADNVKLVL-------VVPGSGLIKKQAEKEGLDK 401 Query: 196 YLNQLGFNIVGYGCTTCIGNSGD-LDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRA 372 GF GC+ C+G + D LD A T NRNFEGR A +R Sbjct: 402 IFESAGFTWREAGCSMCLGMNPDILDPEERCAST-----------SNRNFEGRQGARSR- 449 Query: 373 NYLASPPLVVAYALAG 420 +L SP + A A+ G Sbjct: 450 THLMSPAMAAAAAIKG 465
>LEU2_SYNY3 (P54384) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 468 Score = 59.3 bits (142), Expect = 1e-08 Identities = 46/141 (32%), Positives = 68/141 (48%) Frame = +1 Query: 4 GTRVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKS 183 GT+V + I SCTN + + AA VAK G +V +K + PGS VK+ + + Sbjct: 336 GTKVDVCFIGSCTN-GRLSDLEEAAKVAK-----GHQVAAGVKAFVVPGSEQVKQQAEAA 389 Query: 184 GLQKYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHAL 363 GL + GF GC+ C+ + D D ++A+ S NRNF+GR + Sbjct: 390 GLDQIFQAAGFEWREAGCSMCLAMNPDK--------LQGDQLSAS--SSNRNFKGRQGSA 439 Query: 364 TRANYLASPPLVVAYALAGTV 426 + L SP +V A A+ G V Sbjct: 440 SGRTLLMSPAMVAAAAITGQV 460
>LEU2_NATPD (Q3IRQ4) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 474 Score = 59.3 bits (142), Expect = 1e-08 Identities = 43/144 (29%), Positives = 64/144 (44%), Gaps = 3/144 (2%) Frame = +1 Query: 4 GTRVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKS 183 G + +A + SCTN P++ A ++ G EV ++ + PGS VK + Sbjct: 337 GYNIDVAFLGSCTNARLPDLRSAAEIIK------GREVHDSVRAMVVPGSQRVKAAAEDE 390 Query: 184 GLQKYLNQLGFNIVGYGCTTCIGNSGDL---DESVAAAITDNDVVAAAVLSGNRNFEGRV 354 GL + GF+ GC+ C+G + D DE+ A+ S NRNF GR Sbjct: 391 GLDSVFKEAGFDWREAGCSMCLGMNDDQLVGDEACAS-------------SSNRNFVGRQ 437 Query: 355 HALTRANYLASPPLVVAYALAGTV 426 + L SP +V A A+ G V Sbjct: 438 GSKDGRTVLMSPEMVAAAAVTGEV 461
>LEU2_SYNP6 (Q5MZY3) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 468 Score = 58.5 bits (140), Expect = 2e-08 Identities = 46/141 (32%), Positives = 66/141 (46%) Frame = +1 Query: 4 GTRVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKS 183 GT+V + I SCTN + + AA VA+ G +V IK + PGS VK+ + Sbjct: 336 GTKVDVCFIGSCTN-GRLSDLREAAKVAQ-----GRKVAAGIKAFVVPGSERVKQQAEAE 389 Query: 184 GLQKYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHAL 363 GL + GF GC+ C+ + D E + + S NRNF+GR + Sbjct: 390 GLDQIFTAAGFEWRQAGCSMCLAMNPDKLEGRQISAS----------SSNRNFKGRQGSA 439 Query: 364 TRANYLASPPLVVAYALAGTV 426 + L SP +V A A+AG V Sbjct: 440 SGRTLLMSPAMVAAAAIAGEV 460
>LEU2_ASHGO (Q74ZM9) 3-isopropylmalate dehydratase (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 776 Score = 58.5 bits (140), Expect = 2e-08 Identities = 43/132 (32%), Positives = 64/132 (48%), Gaps = 1/132 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLA-PGSGVVKKYLDKSGLQKYLN 204 I SCTN ++ AA+V G + P +K ++ PGSG+VKK + GL K Sbjct: 354 IGSCTNARIEDLRAAAAVVD------GHRIAPTVKRAMVVPGSGLVKKQAEAEGLDKIFE 407 Query: 205 QLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 GF GC+ C+G + D+ + + A+ + NRNFEGR L+R +L Sbjct: 408 AAGFEWREAGCSMCLGMNPDI-------LGPKERCAS---TSNRNFEGRQGRLSR-THLM 456 Query: 385 SPPLVVAYALAG 420 SP + A + G Sbjct: 457 SPAMAAAAGIMG 468
>LEU2_SYMTH (Q67MJ2) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 481 Score = 58.5 bits (140), Expect = 2e-08 Identities = 42/131 (32%), Positives = 63/131 (48%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN ++ AA+V G +V P ++ + PGSG VK + GL + + Sbjct: 352 IGSCTNGRIEDLRAAAAVVK------GRKVAPGVRAMVVPGSGQVKAQAEAEGLDQIFRE 405 Query: 208 LGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLAS 387 GF GC+ C+G + D+ + + A+ + NRNFEGR R +L S Sbjct: 406 AGFEWREAGCSMCLGMNPDI-------LAPGERCAS---TSNRNFEGRQGKGGR-THLVS 454 Query: 388 PPLVVAYALAG 420 P + A A+AG Sbjct: 455 PAMAAAAAIAG 465
>LEU2_HALMA (Q5V518) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 473 Score = 58.5 bits (140), Expect = 2e-08 Identities = 41/142 (28%), Positives = 65/142 (45%) Frame = +1 Query: 4 GTRVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKS 183 G + +A + SCTN P++ A +V G EV ++ + PGS V++ ++ Sbjct: 337 GYDIDVAFLGSCTNARLPDLRRAARIVK------GREVADDVRAFVVPGSQRVQRAAEEE 390 Query: 184 GLQKYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHAL 363 GL+ + GF GC+ C+G + D E A + S NRNF GR + Sbjct: 391 GLKDIFEEAGFEWRNAGCSMCLGMNEDQLEGDEACAS----------SSNRNFVGRQGSK 440 Query: 364 TRANYLASPPLVVAYALAGTVN 429 L +P +V A A+ G V+ Sbjct: 441 DGRTVLMNPRMVAAAAITGEVS 462
>LEU2_BACSK (Q5WEN5) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 470 Score = 57.8 bits (138), Expect = 3e-08 Identities = 40/131 (30%), Positives = 65/131 (49%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN+ ++ AA++ G +V P ++ + PGS VKK ++ GL + + Sbjct: 343 IGSCTNSRLSDLRAAAAVIN------GRKVAPGVRALIVPGSQRVKKRAEEEGLDQVFKE 396 Query: 208 LGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLAS 387 GF GC+ C+ + D+ + + + A+ + NRNFEGR R +L S Sbjct: 397 AGFEWRDSGCSMCLSMNPDV-------VPEGERCAS---TSNRNFEGRQGKGAR-THLVS 445 Query: 388 PPLVVAYALAG 420 P + A A+AG Sbjct: 446 PAMAAAAAIAG 456
>LEU2_ANASP (Q8YX02) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 467 Score = 57.4 bits (137), Expect = 4e-08 Identities = 44/141 (31%), Positives = 63/141 (44%) Frame = +1 Query: 4 GTRVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKS 183 GT++ + I SCTN ++ AA +AK G V +K + PGS VKK + Sbjct: 336 GTKIDVCFIGSCTNGRLTDLQ-EAAKIAK-----GRRVAAGVKAFVVPGSERVKKAAEAE 389 Query: 184 GLQKYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHAL 363 GL K GF GC+ C+ + D E + + S NRNF+GR + Sbjct: 390 GLDKIFEAAGFEWREPGCSMCLAMNPDKLEGRQISAS----------SSNRNFKGRQGSA 439 Query: 364 TRANYLASPPLVVAYALAGTV 426 + L SP +V A+ G V Sbjct: 440 SGRTLLMSPAMVATAAIQGEV 460
>LEU2_HALVO (Q7ZAG7) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 473 Score = 57.4 bits (137), Expect = 4e-08 Identities = 41/141 (29%), Positives = 63/141 (44%) Frame = +1 Query: 4 GTRVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKS 183 G + +A + SCTN P++ A +V G +V ++ + PGS VK + Sbjct: 337 GYEIDVAFLGSCTNARLPDLRRAAGVVK------GRQVADSVRAMVVPGSQRVKAAAEAE 390 Query: 184 GLQKYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHAL 363 GL + + GF GC+ C+G + D E A+ + S NRNF GR + Sbjct: 391 GLDEVFKEAGFEWREAGCSMCLGMNEDQLEGDEASAS----------SSNRNFIGRQGSK 440 Query: 364 TRANYLASPPLVVAYALAGTV 426 L +P +V A A+ G V Sbjct: 441 DGRTVLMNPRMVAAAAVTGEV 461
>LEU2_GLUOX (Q5FUG3) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 475 Score = 57.0 bits (136), Expect = 5e-08 Identities = 44/139 (31%), Positives = 63/139 (45%) Frame = +1 Query: 4 GTRVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKS 183 GT V + I SCTN+ ++ A +V G V ++ + PGSG+VK + Sbjct: 341 GTPVDVVFIGSCTNSRLEDLRAAADVVR------GRHVAEGVRAMIVPGSGLVKHAAEAE 394 Query: 184 GLQKYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHAL 363 GL K GF GC+ C+G + D +T A+ + NRNFEGR Sbjct: 395 GLDKVFLDAGFEWREAGCSMCLGMNPD-------RLTPGQRCAS---TSNRNFEGRQGPD 444 Query: 364 TRANYLASPPLVVAYALAG 420 R +L SP + A A+ G Sbjct: 445 GR-THLCSPAMAAAAAVTG 462
>LEU2_SCHPO (O14289) 3-isopropylmalate dehydratase (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 758 Score = 57.0 bits (136), Expect = 5e-08 Identities = 43/132 (32%), Positives = 65/132 (49%), Gaps = 1/132 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSL-APGSGVVKKYLDKSGLQKYLN 204 I SCTN+ ++ L AA+V G +V +K ++ PGSG+VKK + GL + Sbjct: 356 IGSCTNSRIEDLRLAAAVVK------GRKVAANVKDAMIVPGSGLVKKMAEAEGLDQIFI 409 Query: 205 QLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 + GF+ GC+ C+G + D + + + NRNFEGR A R +L Sbjct: 410 EAGFDWREAGCSMCLGMNPDQLKPYERCAS----------TSNRNFEGRQGAKGR-THLV 458 Query: 385 SPPLVVAYALAG 420 SP + A A+ G Sbjct: 459 SPAMAAAAAIKG 470
>LEU2_BACHD (Q9K8F0) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 472 Score = 57.0 bits (136), Expect = 5e-08 Identities = 44/143 (30%), Positives = 70/143 (48%), Gaps = 2/143 (1%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN+ ++ A L+ G +V ++ + PGS VK+ +K GL + + Sbjct: 344 IGSCTNSRLSDLRTAAELIK------GRKVADGVRALVVPGSQQVKRAAEKEGLDEIFKE 397 Query: 208 LGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLAS 387 GF GC+ C+G + D + + + A+ + NRNFEGR R +L S Sbjct: 398 AGFEWRDSGCSMCLGMNPD-------TVPEGERCAS---TSNRNFEGRQGKGAR-THLVS 446 Query: 388 PPLVVAYALAG-TVNI-DFEKEP 450 P + A A+AG V++ F+ EP Sbjct: 447 PQMAAAAAIAGHFVDVRTFQSEP 469
>LEU2_STRGN (Q9AIM3) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) (Fragment) Length = 456 Score = 56.6 bits (135), Expect = 7e-08 Identities = 43/132 (32%), Positives = 57/132 (43%), Gaps = 1/132 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN ++ L A VA G + P + + PGS VK+ +K GL K Sbjct: 331 IGSCTNARLSDLQLAAKFVA------GKHIAPNLTAIVVPGSRPVKRVAEKMGLDKIFMD 384 Query: 208 LGFNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 GF GC+ C+G N + + V A T NRNFE R +L Sbjct: 385 AGFEWRDPGCSMCLGMNPDKVPDGVHCAST-----------SNRNFEDR-QGFGAKTHLC 432 Query: 385 SPPLVVAYALAG 420 SP + A A+AG Sbjct: 433 SPAMAAAAAIAG 444
>LEU2_AGRT5 (Q8UBY9) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 56.6 bits (135), Expect = 7e-08 Identities = 47/145 (32%), Positives = 64/145 (44%), Gaps = 6/145 (4%) Frame = +1 Query: 4 GTRVVIAAIT-----SCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKK 168 GTR+ AI SCTN ++ A +V G +V + + PGSG+VK+ Sbjct: 334 GTRITDIAIDRVFIGSCTNGRIEDLRAAAKIVD------GRKVASTVSAMIVPGSGLVKE 387 Query: 169 YLDKSGLQKYLNQLGFNIVGYGCTTCIGNSGD-LDESVAAAITDNDVVAAAVLSGNRNFE 345 +K GL K GF GC+ C+ + D L A T NRNFE Sbjct: 388 QAEKEGLDKIFLDAGFEWREPGCSMCLAMNDDRLKPGERCAST-----------SNRNFE 436 Query: 346 GRVHALTRANYLASPPLVVAYALAG 420 GR +R +L SP + A A+AG Sbjct: 437 GRQGYKSR-THLVSPAMAAAAAIAG 460
>LEU2_GEOKA (Q5KWJ5) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 471 Score = 56.6 bits (135), Expect = 7e-08 Identities = 46/144 (31%), Positives = 70/144 (48%), Gaps = 2/144 (1%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN+ ++ A++V G +V P ++ + PGS VKK + GL + Sbjct: 344 IGSCTNSRLSDLRAAASIVK------GKKVAPGVRALVVPGSQQVKKQAEAEGLAQIFID 397 Query: 208 LGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLAS 387 GF GC+ C+G + D+ I + + A+ + NRNFEGR R +L S Sbjct: 398 AGFEWRDSGCSACLGMNPDI-------IPEGEHCAS---TSNRNFEGRQGKGAR-THLVS 446 Query: 388 PPLVVAYALAG-TVNI-DFEKEPV 453 P + A A+ G V++ E EPV Sbjct: 447 PVMAAAAAIYGHFVDVRQLEAEPV 470
>LEU2_RALSO (Q8XXX3) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 56.2 bits (134), Expect = 9e-08 Identities = 45/133 (33%), Positives = 63/133 (47%), Gaps = 2/133 (1%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLA-PGSGVVKKYLDKSGLQKYLN 204 I SCTN+ ++ A +V K LG + +K ++ PGSG+VK+ ++ GL K Sbjct: 344 IGSCTNSRIEDMRAAAWVVQK----LGKRIASNVKLAMVVPGSGLVKEQAEREGLDKIFK 399 Query: 205 QLGFNIVGYGCTTCIGNSGD-LDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYL 381 GF GC+ C+ + D L+ A T NRNFEGR A R +L Sbjct: 400 AAGFEWREPGCSMCLAMNADRLEPGERCAST-----------SNRNFEGRQGAGGR-THL 447 Query: 382 ASPPLVVAYALAG 420 SP + A AL G Sbjct: 448 VSPAMAAAAALEG 460
>LEU2_RALEJ (Q46YV7) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 56.2 bits (134), Expect = 9e-08 Identities = 45/133 (33%), Positives = 64/133 (48%), Gaps = 2/133 (1%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLA-PGSGVVKKYLDKSGLQKYLN 204 I SCTN+ ++ A +V K LG +V +K ++ PGSG+VK+ ++ GL K Sbjct: 344 IGSCTNSRIEDMRAAAWVVQK----LGRKVASNVKLAMVVPGSGLVKEQAEREGLDKVFK 399 Query: 205 QLGFNIVGYGCTTCIGNSGD-LDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYL 381 GF GC+ C+ + D L+ A T NRNFEGR A R +L Sbjct: 400 AAGFEWREPGCSMCLAMNADRLEPGERCAST-----------SNRNFEGRQGAGGR-THL 447 Query: 382 ASPPLVVAYALAG 420 SP + A A+ G Sbjct: 448 VSPAMAAAAAIEG 460
>LEU2_BRUSU (Q8FYG9) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 56.2 bits (134), Expect = 9e-08 Identities = 42/132 (31%), Positives = 59/132 (44%), Gaps = 1/132 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN ++ A +V G +V P + + PGSG+VK+ + GL K + Sbjct: 347 IGSCTNGRIEDLRAAAKVVE------GKKVAPTVNAMIVPGSGLVKEQAEAEGLHKIFIE 400 Query: 208 LGFNIVGYGCTTCIGNSGD-LDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 GF+ GC+ C+ + D L A T NRNFEGR +L Sbjct: 401 AGFDWREPGCSMCLAMNDDRLKPGERCAST-----------SNRNFEGR-QGFKGRTHLV 448 Query: 385 SPPLVVAYALAG 420 SP + A A+AG Sbjct: 449 SPAMAAAAAIAG 460
>LEU2_BRUME (Q8YJC9) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 56.2 bits (134), Expect = 9e-08 Identities = 42/132 (31%), Positives = 59/132 (44%), Gaps = 1/132 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN ++ A +V G +V P + + PGSG+VK+ + GL K + Sbjct: 347 IGSCTNGRIEDLRAAAKVVE------GKKVAPTVNAMIVPGSGLVKEQAEAEGLHKIFIE 400 Query: 208 LGFNIVGYGCTTCIGNSGD-LDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 GF+ GC+ C+ + D L A T NRNFEGR +L Sbjct: 401 AGFDWREPGCSMCLAMNDDRLKPGERCAST-----------SNRNFEGR-QGFKGRTHLV 448 Query: 385 SPPLVVAYALAG 420 SP + A A+AG Sbjct: 449 SPAMAAAAAIAG 460
>LEU2_RHIME (Q92L76) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 55.8 bits (133), Expect = 1e-07 Identities = 45/145 (31%), Positives = 64/145 (44%), Gaps = 6/145 (4%) Frame = +1 Query: 4 GTRVVIAAIT-----SCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKK 168 GT++ AI SCTN ++ A +V G +V P + + PGSG+VK+ Sbjct: 334 GTKITDIAIDRVFIGSCTNGRIEDLRAVAEVVE------GRKVAPTVSAMIVPGSGLVKE 387 Query: 169 YLDKSGLQKYLNQLGFNIVGYGCTTCIGNSGD-LDESVAAAITDNDVVAAAVLSGNRNFE 345 + GL K + GF+ GC+ C+ + D L A T NRNFE Sbjct: 388 QAEAEGLDKIFKEAGFDWREPGCSMCLAMNDDRLKPGERCAST-----------SNRNFE 436 Query: 346 GRVHALTRANYLASPPLVVAYALAG 420 GR +L SP + A A+AG Sbjct: 437 GR-QGFKGRTHLLSPAMAAAAAVAG 460
>LEU2_OCEIH (Q8EN69) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 468 Score = 55.5 bits (132), Expect = 2e-07 Identities = 42/131 (32%), Positives = 62/131 (47%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN+ ++ AA+V G +VK I+ + PGS +VK+ ++ GL + Sbjct: 342 IGSCTNSRLSDLKKAAAIVK------GKKVKAGIRAMVVPGSFLVKQKAEEIGLDQVFMD 395 Query: 208 LGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLAS 387 GF GC+ C+G + D+ V A + NRNFEGR R +L S Sbjct: 396 AGFEWRNSGCSMCLGMNDDI---VPAG-------GRCASTSNRNFEGRQGNGAR-THLVS 444 Query: 388 PPLVVAYALAG 420 P + A A+ G Sbjct: 445 PEMAAAAAIEG 455
>LEU21_BRAJA (Q89X98) 3-isopropylmalate dehydratase large subunit 1 (EC| 4.2.1.33) (Isopropylmalate isomerase 1) (Alpha-IPM isomerase 1) (IPMI 1) Length = 477 Score = 55.1 bits (131), Expect = 2e-07 Identities = 47/141 (33%), Positives = 67/141 (47%) Frame = +1 Query: 4 GTRVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKS 183 GT+V I SCTN S + + AA VA+ G +V P ++ + PGS VK+ Sbjct: 346 GTKVDWVFIGSCTN-SRLSDLRAAAEVAR-----GRKVAPGVRAWVVPGSETVKRDAVAE 399 Query: 184 GLQKYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHAL 363 GL K GF GC+ C+ +G E+V +V + NRNF GR Sbjct: 400 GLDKIFIDAGFEWREPGCSMCLAANG---ETVPPG-------QRSVSTSNRNFIGRQGPR 449 Query: 364 TRANYLASPPLVVAYALAGTV 426 R +LASP + A A++G + Sbjct: 450 AR-THLASPAMAAAAAVSGAI 469
>LEU2_COLP3 (Q47WG2) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 471 Score = 55.1 bits (131), Expect = 2e-07 Identities = 42/131 (32%), Positives = 62/131 (47%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN+ ++ A +V K G +V I + PGS VK+ + GL K Sbjct: 348 IGSCTNSRIEDLRAAAGVVQKYE---GQQVVKTIDAIIVPGSYRVKEQAESEGLDKIFTD 404 Query: 208 LGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLAS 387 GF GC+ C+G + D+ + + D A+ + NRNFEGR +R +L S Sbjct: 405 AGFEWRLPGCSMCLGMNDDV-------LEEGDRCAS---TSNRNFEGRQGRGSR-THLVS 453 Query: 388 PPLVVAYALAG 420 P + A A+ G Sbjct: 454 PEMAAAAAITG 464
>ACON_GRAVE (P49609) Aconitate hydratase, mitochondrial precursor (EC 4.2.1.3)| (Citrate hydro-lyase) (Aconitase) Length = 779 Score = 54.7 bits (130), Expect = 3e-07 Identities = 49/171 (28%), Positives = 83/171 (48%), Gaps = 3/171 (1%) Frame = +1 Query: 13 VVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQ 192 + + I SCTN+S + M +A V K+A G++ K ++ PGS V+ + + G+ Sbjct: 375 LTVGLIGSCTNSSYED-MARSASVVKQALSHGVKSKSIF--NITPGSEQVRATISRDGIL 431 Query: 193 KYLNQLGFNIVGYGCTTCIG--NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALT 366 + G ++ C CIG N D+ + T N ++ S NRNF R Sbjct: 432 DTFTEAGGTVLANACGPCIGQWNRSDVPKG-----TPNSIIT----SFNRNFSQRNDGNP 482 Query: 367 RAN-YLASPPLVVAYALAGTVNIDFEKEPVGISKDGKEVYFRDIWPSTDEI 516 + + ++ASP +V A +LAG++ + + + DG E F+ PS DE+ Sbjct: 483 QTHAFVASPEIVTAMSLAGSLKFNPATDSLQ-GADGAE--FKLAAPSGDEL 530
>LEU2_BURPS (Q63JK9) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 54.7 bits (130), Expect = 3e-07 Identities = 43/133 (32%), Positives = 61/133 (45%), Gaps = 2/133 (1%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLA-PGSGVVKKYLDKSGLQKYLN 204 I SCTN ++ A +V K L V P ++ ++ PGSG+VK ++ GL K Sbjct: 344 IGSCTNARIEDIRAAAYVVKK----LNRRVAPNVRLAMVVPGSGLVKAQAEREGLDKVFT 399 Query: 205 QLGFNIVGYGCTTCIGNSGD-LDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYL 381 + GF GC+ C+ + D L+ A T NRNFEGR R +L Sbjct: 400 EAGFEWREPGCSMCLAMNADRLEPGERCAST-----------SNRNFEGRQGQGGR-THL 447 Query: 382 ASPPLVVAYALAG 420 SP + A A+ G Sbjct: 448 VSPAMAAAAAIEG 460
>LEU2_BURMA (Q62AI6) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 54.7 bits (130), Expect = 3e-07 Identities = 43/133 (32%), Positives = 61/133 (45%), Gaps = 2/133 (1%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLA-PGSGVVKKYLDKSGLQKYLN 204 I SCTN ++ A +V K L V P ++ ++ PGSG+VK ++ GL K Sbjct: 344 IGSCTNARIEDIRAAAYVVKK----LNRRVAPNVRLAMVVPGSGLVKAQAEREGLDKVFT 399 Query: 205 QLGFNIVGYGCTTCIGNSGD-LDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYL 381 + GF GC+ C+ + D L+ A T NRNFEGR R +L Sbjct: 400 EAGFEWREPGCSMCLAMNADRLEPGERCAST-----------SNRNFEGRQGQGGR-THL 447 Query: 382 ASPPLVVAYALAG 420 SP + A A+ G Sbjct: 448 VSPAMAAAAAIEG 460
>LEU2_PSEF5 (Q4KF08) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 472 Score = 54.7 bits (130), Expect = 3e-07 Identities = 46/132 (34%), Positives = 64/132 (48%), Gaps = 1/132 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLA-PGSGVVKKYLDKSGLQKYLN 204 I SCTN S + AA++AK G +V IK ++ PGSG+VK + GL K Sbjct: 349 IGSCTN-SRIEDLRAAAVIAK-----GRKVASTIKQAIVVPGSGLVKAQAESEGLDKIFL 402 Query: 205 QLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 + GF GC+ C+ + D ES + + NRNFEGR A R +L Sbjct: 403 EAGFEWREPGCSMCLAMNPDRLESGEHCAS----------TSNRNFEGRQGAGGR-THLV 451 Query: 385 SPPLVVAYALAG 420 SP + A A++G Sbjct: 452 SPAMAAAAAVSG 463
>LEU2_STRT2 (Q5M406) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 460 Score = 54.7 bits (130), Expect = 3e-07 Identities = 41/132 (31%), Positives = 58/132 (43%), Gaps = 1/132 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN ++ L A +V G ++ P + + PGS VK+ +K GL K Sbjct: 335 IGSCTNARLSDLQLAARIVK------GKKISPNLTAIVVPGSRPVKRAAEKIGLDKIFKD 388 Query: 208 LGFNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 GF GC+ C+G N + + V A T NRNFE R +L Sbjct: 389 AGFEWREPGCSMCLGMNPDKVPDGVHCAST-----------SNRNFEDR-QGFGAKTHLC 436 Query: 385 SPPLVVAYALAG 420 SP + A A++G Sbjct: 437 SPAMAAAAAISG 448
>LEU2_STRT1 (Q5LZF4) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 460 Score = 54.7 bits (130), Expect = 3e-07 Identities = 41/132 (31%), Positives = 58/132 (43%), Gaps = 1/132 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN ++ L A +V G ++ P + + PGS VK+ +K GL K Sbjct: 335 IGSCTNARLSDLQLAARIVK------GKKISPNLTAIVVPGSRPVKRAAEKIGLDKIFKD 388 Query: 208 LGFNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 GF GC+ C+G N + + V A T NRNFE R +L Sbjct: 389 AGFEWREPGCSMCLGMNPDKVPDGVHCAST-----------SNRNFEDR-QGFGAKTHLC 436 Query: 385 SPPLVVAYALAG 420 SP + A A++G Sbjct: 437 SPAMAAAAAISG 448
>LEU2_PSEPK (Q88LE8) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 477 Score = 54.3 bits (129), Expect = 4e-07 Identities = 46/132 (34%), Positives = 64/132 (48%), Gaps = 1/132 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLA-PGSGVVKKYLDKSGLQKYLN 204 I SCTN S + AA +AK G +V +K ++ PGSG+VK ++ GL K Sbjct: 349 IGSCTN-SRIEDLRAAAEIAK-----GRKVAASVKQAIVVPGSGLVKAQAEREGLDKIFL 402 Query: 205 QLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 + GF GC+ C+ + D ES + + NRNFEGR A R +L Sbjct: 403 EAGFEWREPGCSMCLAMNPDRLESGEHCAS----------TSNRNFEGRQGAGGR-THLV 451 Query: 385 SPPLVVAYALAG 420 SP + A A+AG Sbjct: 452 SPAMAAAAAVAG 463
>LEU2_USTMA (P49601) 3-isopropylmalate dehydratase (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 773 Score = 54.3 bits (129), Expect = 4e-07 Identities = 42/131 (32%), Positives = 61/131 (46%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN ++ A ++ G +V + L PGSG+VKK + GL K Sbjct: 352 IGSCTNARIEDLRAAARVLH------GRKVADGLYCMLVPGSGLVKKQAEAEGLDKIFQA 405 Query: 208 LGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLAS 387 GF+ GC+ C+G + D + + A+ + NRNFEGR A R +L S Sbjct: 406 AGFDWREAGCSMCLGMNPD-------QLAPGERCAS---TSNRNFEGRQGAGGR-THLMS 454 Query: 388 PPLVVAYALAG 420 P + A A+ G Sbjct: 455 PAMAAACAVTG 465
>LEU2_STAHJ (Q4L7U2) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 456 Score = 53.9 bits (128), Expect = 5e-07 Identities = 42/130 (32%), Positives = 57/130 (43%), Gaps = 1/130 (0%) Frame = +1 Query: 34 SCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQLG 213 SCTN +++ + +V G +V P I + PGS VKK + GL K G Sbjct: 335 SCTNARLSDLVEASRIVK------GKQVHPKITAIVVPGSRSVKKEAEALGLDKIFKDAG 388 Query: 214 FNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLASP 390 F GC+ C+G N + E + A T NRNFEGR R +L SP Sbjct: 389 FQWREPGCSMCLGMNPDQVPEGIHCAST-----------SNRNFEGRQGKGAR-THLVSP 436 Query: 391 PLVVAYALAG 420 + A A+ G Sbjct: 437 AMAAAAAIEG 446
>LEU2_RHILO (Q98EF1) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 53.9 bits (128), Expect = 5e-07 Identities = 39/131 (29%), Positives = 60/131 (45%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN ++ A ++ K V P + + PGSG+VK+ + GL K Sbjct: 347 IGSCTNGRIEDLRAAAKVIEGKT------VNPRVNAMIVPGSGLVKEQAEAEGLDKIFLA 400 Query: 208 LGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLAS 387 GF+ GC+ C+ + D + ++ A+ + NRNFEGR +L S Sbjct: 401 AGFDWREPGCSMCLAMNDD-------RLKPHERCAS---TSNRNFEGR-QGFKGRTHLVS 449 Query: 388 PPLVVAYALAG 420 P + A A+AG Sbjct: 450 PAMAAAAAIAG 460
>LEU2_STAEQ (Q5HMF7) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 456 Score = 53.5 bits (127), Expect = 6e-07 Identities = 42/130 (32%), Positives = 57/130 (43%), Gaps = 1/130 (0%) Frame = +1 Query: 34 SCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQLG 213 SCTN +++ + ++ G +V P I + PGS VKK + GL K G Sbjct: 335 SCTNARLSDLIEASHIIK------GQQVHPNITAIVVPGSRTVKKEAEALGLDKLFKDAG 388 Query: 214 FNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLASP 390 F GC+ C+G N + E V A T NRNFEGR R +L SP Sbjct: 389 FEWREPGCSMCLGMNPDQVPEGVHCAST-----------SNRNFEGRQGKGAR-THLVSP 436 Query: 391 PLVVAYALAG 420 + A A+ G Sbjct: 437 AMAAAAAING 446
>LEU2_BUCAP (O85065) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 53.5 bits (127), Expect = 6e-07 Identities = 40/131 (30%), Positives = 63/131 (48%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN+ ++ A ++ K ++ IK + PGSG VK +K GL K Sbjct: 344 IGSCTNSRIEDLRSAATILKNK------KISKNIKAIVVPGSGSVKNQAEKEGLDKIFID 397 Query: 208 LGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLAS 387 GF GC+ C+G + D ++D + A+ + NRNFEGR R + ++ Sbjct: 398 AGFEWRLPGCSMCLGMNND-------KLSDGERCAS---TSNRNFEGRQGRGGRTHLVS- 446 Query: 388 PPLVVAYALAG 420 P++ A A+ G Sbjct: 447 -PIMAAAAIYG 456
>LEU2_PSEAE (Q9HZA3) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 474 Score = 53.5 bits (127), Expect = 6e-07 Identities = 47/132 (35%), Positives = 64/132 (48%), Gaps = 1/132 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLA-PGSGVVKKYLDKSGLQKYLN 204 I SCTN S + AA VA+ G +V IK +L PGSG+VK+ +K GL + Sbjct: 350 IGSCTN-SRIEDLRAAAEVAR-----GRKVAATIKQALVVPGSGLVKEQAEKEGLDRIFI 403 Query: 205 QLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 + GF GC+ C+ + D ES + + NRNFEGR A R +L Sbjct: 404 EAGFEWREPGCSMCLAMNPDRLESGEHCAS----------TSNRNFEGRQGAGGR-THLV 452 Query: 385 SPPLVVAYALAG 420 SP + A A+ G Sbjct: 453 SPAMAAAAAVNG 464
>LEU2_SALPA (Q5PDG3) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 466 Score = 53.1 bits (126), Expect = 8e-07 Identities = 46/132 (34%), Positives = 60/132 (45%), Gaps = 1/132 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN S + AA VAK G +V P ++ + PGSG VK + GL K + Sbjct: 344 IGSCTN-SRIEDLRAAAEVAK-----GRKVAPGVQALVVPGSGPVKAQAEAEGLDKIFIE 397 Query: 208 LGFNIVGYGCTTCIGNSGD-LDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 GF GC+ C+ + D L+ A T NRNFEGR R +L Sbjct: 398 AGFEWRLPGCSMCLAMNNDRLNPGERCAST-----------SNRNFEGRQGRGGR-THLV 445 Query: 385 SPPLVVAYALAG 420 SP + A A+ G Sbjct: 446 SPAMAAAAAVTG 457
>LEU21_SALCH (Q57TE8) 3-isopropylmalate dehydratase large subunit 1 (EC| 4.2.1.33) (Isopropylmalate isomerase 1) (Alpha-IPM isomerase 1) (IPMI 1) Length = 466 Score = 53.1 bits (126), Expect = 8e-07 Identities = 46/132 (34%), Positives = 60/132 (45%), Gaps = 1/132 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN S + AA VAK G +V P ++ + PGSG VK + GL K + Sbjct: 344 IGSCTN-SRIEDLRAAAEVAK-----GRKVAPGVQALVVPGSGPVKAQAEAEGLDKIFIE 397 Query: 208 LGFNIVGYGCTTCIGNSGD-LDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 GF GC+ C+ + D L+ A T NRNFEGR R +L Sbjct: 398 AGFEWRLPGCSMCLAMNNDRLNPGERCAST-----------SNRNFEGRQGRGGR-THLV 445 Query: 385 SPPLVVAYALAG 420 SP + A A+ G Sbjct: 446 SPAMAAAAAVTG 457
>LEU2_STAES (Q8CNL1) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 456 Score = 53.1 bits (126), Expect = 8e-07 Identities = 42/130 (32%), Positives = 57/130 (43%), Gaps = 1/130 (0%) Frame = +1 Query: 34 SCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQLG 213 SCTN +++ + ++ G +V P I + PGS VKK + GL K G Sbjct: 335 SCTNARLSDLIEASHIIK------GQQVHPNITAIVVPGSRTVKKEAEALGLDKLFKDAG 388 Query: 214 FNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLASP 390 F GC+ C+G N + E V A T NRNFEGR R +L SP Sbjct: 389 FEWREPGCSMCLGMNPDQVPEGVHCAST-----------SNRNFEGRQGKGAR-THLVSP 436 Query: 391 PLVVAYALAG 420 + A A+ G Sbjct: 437 VMAAAAAING 446
>LEU2_STAAW (P58947) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 456 Score = 53.1 bits (126), Expect = 8e-07 Identities = 43/130 (33%), Positives = 57/130 (43%), Gaps = 1/130 (0%) Frame = +1 Query: 34 SCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQLG 213 SCTN +++ + +V G +V P I + PGS VKK +K GL G Sbjct: 335 SCTNARLSDLIEASHIVK------GNKVHPNITAIVVPGSRTVKKEAEKLGLDTIFKNAG 388 Query: 214 FNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLASP 390 F GC+ C+G N + E V A T NRNFEGR R +L SP Sbjct: 389 FEWREPGCSMCLGMNPDQVPEGVHCAST-----------SNRNFEGRQGKGAR-THLVSP 436 Query: 391 PLVVAYALAG 420 + A A+ G Sbjct: 437 AMAAAAAIHG 446
>LEU2_STAAS (Q6G7P9) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 456 Score = 53.1 bits (126), Expect = 8e-07 Identities = 43/130 (33%), Positives = 57/130 (43%), Gaps = 1/130 (0%) Frame = +1 Query: 34 SCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQLG 213 SCTN +++ + +V G +V P I + PGS VKK +K GL G Sbjct: 335 SCTNARLSDLIEASHIVK------GNKVHPNITAIVVPGSRTVKKEAEKLGLDTIFKNAG 388 Query: 214 FNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLASP 390 F GC+ C+G N + E V A T NRNFEGR R +L SP Sbjct: 389 FEWREPGCSMCLGMNPDQVPEGVHCAST-----------SNRNFEGRQGKGAR-THLVSP 436 Query: 391 PLVVAYALAG 420 + A A+ G Sbjct: 437 AMAAAAAIHG 446
>LEU2_STAAN (P63436) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 456 Score = 53.1 bits (126), Expect = 8e-07 Identities = 43/130 (33%), Positives = 57/130 (43%), Gaps = 1/130 (0%) Frame = +1 Query: 34 SCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQLG 213 SCTN +++ + +V G +V P I + PGS VKK +K GL G Sbjct: 335 SCTNARLSDLIEASHIVK------GNKVHPNITAIVVPGSRTVKKEAEKLGLDTIFKNAG 388 Query: 214 FNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLASP 390 F GC+ C+G N + E V A T NRNFEGR R +L SP Sbjct: 389 FEWREPGCSMCLGMNPDQVPEGVHCAST-----------SNRNFEGRQGKGAR-THLVSP 436 Query: 391 PLVVAYALAG 420 + A A+ G Sbjct: 437 AMAAAAAIHG 446
>LEU2_STAAM (P63435) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 456 Score = 53.1 bits (126), Expect = 8e-07 Identities = 43/130 (33%), Positives = 57/130 (43%), Gaps = 1/130 (0%) Frame = +1 Query: 34 SCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQLG 213 SCTN +++ + +V G +V P I + PGS VKK +K GL G Sbjct: 335 SCTNARLSDLIEASHIVK------GNKVHPNITAIVVPGSRTVKKEAEKLGLDTIFKNAG 388 Query: 214 FNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLASP 390 F GC+ C+G N + E V A T NRNFEGR R +L SP Sbjct: 389 FEWREPGCSMCLGMNPDQVPEGVHCAST-----------SNRNFEGRQGKGAR-THLVSP 436 Query: 391 PLVVAYALAG 420 + A A+ G Sbjct: 437 AMAAAAAIHG 446
>LEU2_STAAC (Q5HEE2) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 456 Score = 53.1 bits (126), Expect = 8e-07 Identities = 43/130 (33%), Positives = 57/130 (43%), Gaps = 1/130 (0%) Frame = +1 Query: 34 SCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQLG 213 SCTN +++ + +V G +V P I + PGS VKK +K GL G Sbjct: 335 SCTNARLSDLIEASHIVK------GNKVHPNITAIVVPGSRTVKKEAEKLGLDTIFKNAG 388 Query: 214 FNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLASP 390 F GC+ C+G N + E V A T NRNFEGR R +L SP Sbjct: 389 FEWREPGCSMCLGMNPDQVPEGVHCAST-----------SNRNFEGRQGKGAR-THLVSP 436 Query: 391 PLVVAYALAG 420 + A A+ G Sbjct: 437 AMAAAAAIHG 446
>LEU2_NEIMB (Q9JZI5) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 53.1 bits (126), Expect = 8e-07 Identities = 44/138 (31%), Positives = 65/138 (47%), Gaps = 2/138 (1%) Frame = +1 Query: 13 VVIAAITSCTNTSNPNVMLGAALVA--KKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSG 186 V I I SCTN+ ++ AA+ KKA ++ + + PGSG+VK+ +K G Sbjct: 341 VDIVFIGSCTNSRIEDLREAAAIAKDRKKAANVQ-------RVLIVPGSGLVKEQAEKEG 393 Query: 187 LQKYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALT 366 L K + GF GC+ C+ + D +T A+ + NRNFEGR Sbjct: 394 LDKIFIEAGFEWREPGCSMCLAMNAD-------RLTPGQRCAS---TSNRNFEGRQGNGG 443 Query: 367 RANYLASPPLVVAYALAG 420 R +L SP + A A+ G Sbjct: 444 R-THLVSPAMAAAAAVTG 460
>LEU2_NEIMA (Q9JU82) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 53.1 bits (126), Expect = 8e-07 Identities = 44/138 (31%), Positives = 65/138 (47%), Gaps = 2/138 (1%) Frame = +1 Query: 13 VVIAAITSCTNTSNPNVMLGAALVA--KKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSG 186 V I I SCTN+ ++ AA+ KKA ++ + + PGSG+VK+ +K G Sbjct: 341 VDIVFIGSCTNSRVEDLREAAAIAKDRKKAANVQ-------RVLIVPGSGLVKEQAEKEG 393 Query: 187 LQKYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALT 366 L K + GF GC+ C+ + D +T A+ + NRNFEGR Sbjct: 394 LDKIFIEAGFEWREPGCSMCLAMNAD-------RLTPGQRCAS---TSNRNFEGRQGNGG 443 Query: 367 RANYLASPPLVVAYALAG 420 R +L SP + A A+ G Sbjct: 444 R-THLVSPAMAAAAAVTG 460
>LEU2_SYNPX (Q7U9J4) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 472 Score = 53.1 bits (126), Expect = 8e-07 Identities = 42/141 (29%), Positives = 59/141 (41%) Frame = +1 Query: 4 GTRVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKS 183 G V + I SCTN ++ AA+ G V IK + PGS V K + Sbjct: 336 GVPVDVCFIGSCTNGRLSDLRAAAAVAR------GRHVADGIKAFVVPGSEQVAKAAEAE 389 Query: 184 GLQKYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHAL 363 GL + GF GC+ C+ + D E + + S NRNF+GR + Sbjct: 390 GLDRVFQDAGFEWREPGCSMCLAMNPDRLEGRQISAS----------SSNRNFKGRQGSA 439 Query: 364 TRANYLASPPLVVAYALAGTV 426 + L SP +V A A+ G V Sbjct: 440 SGRTLLMSPAMVAAAAVHGQV 460
>LEU2_SALTI (Q8Z9I2) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 465 Score = 53.1 bits (126), Expect = 8e-07 Identities = 46/132 (34%), Positives = 60/132 (45%), Gaps = 1/132 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN S + AA VAK G +V P ++ + PGSG VK + GL K + Sbjct: 343 IGSCTN-SRIEDLRAAAEVAK-----GRKVAPGVQALVVPGSGPVKAQAEAEGLDKIFIE 396 Query: 208 LGFNIVGYGCTTCIGNSGD-LDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 GF GC+ C+ + D L+ A T NRNFEGR R +L Sbjct: 397 AGFEWRLPGCSMCLAMNNDRLNPGERCAST-----------SNRNFEGRQGRGGR-THLV 444 Query: 385 SPPLVVAYALAG 420 SP + A A+ G Sbjct: 445 SPAMAAAAAVTG 456
>LEU21_SALTY (P15717) 3-isopropylmalate dehydratase large subunit 1 (EC| 4.2.1.33) (Isopropylmalate isomerase 1) (Alpha-IPM isomerase 1) (IPMI 1) Length = 465 Score = 53.1 bits (126), Expect = 8e-07 Identities = 46/132 (34%), Positives = 60/132 (45%), Gaps = 1/132 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN S + AA VAK G +V P ++ + PGSG VK + GL K + Sbjct: 343 IGSCTN-SRIEDLRAAAEVAK-----GRKVAPGVQALVVPGSGPVKAQAEAEGLDKIFIE 396 Query: 208 LGFNIVGYGCTTCIGNSGD-LDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 GF GC+ C+ + D L+ A T NRNFEGR R +L Sbjct: 397 AGFEWRLPGCSMCLAMNNDRLNPGERCAST-----------SNRNFEGRQGRGGR-THLV 444 Query: 385 SPPLVVAYALAG 420 SP + A A+ G Sbjct: 445 SPAMAAAAAVTG 456
>LEU2_BACCR (Q81G10) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 464 Score = 52.8 bits (125), Expect = 1e-06 Identities = 42/140 (30%), Positives = 67/140 (47%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN+ ++ + A++V G +VK ++ + PGS V++ GL + + Sbjct: 334 IGSCTNSRLSDLEIAASVVK------GKKVKEGVRALVVPGSQRVREAAMHKGLHRIFEE 387 Query: 208 LGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLAS 387 GF GC+ C+G + D + + + A+ + NRNFEGR R +L S Sbjct: 388 AGFEWREPGCSMCLGMNPD-------QVPEGEHCAS---TSNRNFEGRQGKGAR-THLVS 436 Query: 388 PPLVVAYALAGTVNIDFEKE 447 P + A AL G +D KE Sbjct: 437 PAMAAAAALYGHF-VDIRKE 455
>LEU2_SHISS (Q3Z5T8) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 466 Score = 52.8 bits (125), Expect = 1e-06 Identities = 45/132 (34%), Positives = 60/132 (45%), Gaps = 1/132 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN S + AA +AK G +V P ++ + PGSG VK + GL K + Sbjct: 344 IGSCTN-SRIEDLRAAAEIAK-----GRKVAPGVQALVVPGSGPVKAQAEAEGLDKIFIE 397 Query: 208 LGFNIVGYGCTTCIGNSGD-LDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 GF GC+ C+ + D L+ A T NRNFEGR R +L Sbjct: 398 AGFEWRLPGCSMCLAMNNDRLNPGERCAST-----------SNRNFEGRQGRGGR-THLV 445 Query: 385 SPPLVVAYALAG 420 SP + A A+ G Sbjct: 446 SPAMAAAAAVTG 457
>LEU2_SHIFL (Q821C2) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 466 Score = 52.8 bits (125), Expect = 1e-06 Identities = 45/132 (34%), Positives = 60/132 (45%), Gaps = 1/132 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN S + AA +AK G +V P ++ + PGSG VK + GL K + Sbjct: 344 IGSCTN-SRIEDLRAAAEIAK-----GRKVAPGVQALVVPGSGPVKAQAEAEGLDKIFIE 397 Query: 208 LGFNIVGYGCTTCIGNSGD-LDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 GF GC+ C+ + D L+ A T NRNFEGR R +L Sbjct: 398 AGFEWRLPGCSMCLAMNNDRLNPGERCAST-----------SNRNFEGRQGRGGR-THLV 445 Query: 385 SPPLVVAYALAG 420 SP + A A+ G Sbjct: 446 SPAMAAAAAVTG 457
>LEU2_SHIDS (Q32K22) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 466 Score = 52.8 bits (125), Expect = 1e-06 Identities = 45/132 (34%), Positives = 60/132 (45%), Gaps = 1/132 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN S + AA +AK G +V P ++ + PGSG VK + GL K + Sbjct: 344 IGSCTN-SRIEDLRAAAEIAK-----GRKVAPGVQALVVPGSGPVKAQAEAEGLDKIFIE 397 Query: 208 LGFNIVGYGCTTCIGNSGD-LDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 GF GC+ C+ + D L+ A T NRNFEGR R +L Sbjct: 398 AGFEWRLPGCSMCLAMNNDRLNPGERCAST-----------SNRNFEGRQGRGGR-THLV 445 Query: 385 SPPLVVAYALAG 420 SP + A A+ G Sbjct: 446 SPAMAAAAAVTG 457
>LEU2_SHIBS (Q326G3) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 466 Score = 52.8 bits (125), Expect = 1e-06 Identities = 45/132 (34%), Positives = 60/132 (45%), Gaps = 1/132 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN S + AA +AK G +V P ++ + PGSG VK + GL K + Sbjct: 344 IGSCTN-SRIEDLRAAAEIAK-----GRKVAPGVQALVVPGSGQVKAQAEAEGLDKIFIE 397 Query: 208 LGFNIVGYGCTTCIGNSGD-LDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 GF GC+ C+ + D L+ A T NRNFEGR R +L Sbjct: 398 AGFEWRLPGCSMCLAMNNDRLNPGERCAST-----------SNRNFEGRQGRGGR-THLV 445 Query: 385 SPPLVVAYALAG 420 SP + A A+ G Sbjct: 446 SPAMAAAAAVTG 457
>LEU2_NITEU (Q82WI9) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 470 Score = 52.8 bits (125), Expect = 1e-06 Identities = 42/132 (31%), Positives = 62/132 (46%), Gaps = 1/132 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLA-PGSGVVKKYLDKSGLQKYLN 204 I SCTN+ ++ A +V G + P I+ ++ PGSG+VK +K GL K Sbjct: 346 IGSCTNSRIEDLRAAAEIVK------GKRIAPNIRLAMVVPGSGLVKSMAEKEGLDKIFL 399 Query: 205 QLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 GF GC+ C+ + D + + A+ + NRNFEGR R +L Sbjct: 400 SAGFEWREPGCSMCLAMNDD-------RLLPGERCAS---TSNRNFEGRQGPGGR-THLV 448 Query: 385 SPPLVVAYALAG 420 SP + A A+AG Sbjct: 449 SPAMAAAAAIAG 460
>LEU2_NITOC (Q3J716) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 52.8 bits (125), Expect = 1e-06 Identities = 46/136 (33%), Positives = 63/136 (46%), Gaps = 2/136 (1%) Frame = +1 Query: 19 IAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLA-PGSGVVKKYLDKSGLQK 195 I I SCTN ++ A +VA G +V IK +L PGSG+VK+ + GL + Sbjct: 342 IIFIGSCTNARIEDLREAAKVVA------GHKVAGNIKQALVVPGSGLVKRQAETEGLDQ 395 Query: 196 YLNQLGFNIVGYGCTTCIGNSGD-LDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRA 372 + GF GC+ C+ + D L+ A T NRNFEGR R Sbjct: 396 IFKEAGFEWREPGCSMCLAMNADRLEPEERCAST-----------SNRNFEGRQGQGGR- 443 Query: 373 NYLASPPLVVAYALAG 420 +L SP + A A+AG Sbjct: 444 THLVSPAMAAAAAVAG 459
>LEU2_STRMU (Q8DTG4) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 461 Score = 52.8 bits (125), Expect = 1e-06 Identities = 41/130 (31%), Positives = 57/130 (43%), Gaps = 1/130 (0%) Frame = +1 Query: 34 SCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQLG 213 SCTN ++ + A VA G + P + + PGS VK+ +K GL K G Sbjct: 337 SCTNARLSDLKVAAKYVA------GKHIAPNLTAIVVPGSRPVKQAAEKIGLDKIFLDAG 390 Query: 214 FNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLASP 390 F GC+ C+G N + E + A T NRNFE R + +L SP Sbjct: 391 FEWRDPGCSMCLGMNPDKVPEGMHCAST-----------SNRNFEDR-QGVGAKTHLCSP 438 Query: 391 PLVVAYALAG 420 + A A+AG Sbjct: 439 AMAAAAAIAG 448
>HACA_THET2 (Q9ZNE0) Probable homoaconitase large subunit (EC 4.2.1.36)| (Homoaconitate hydratase) Length = 418 Score = 52.8 bits (125), Expect = 1e-06 Identities = 45/152 (29%), Positives = 66/152 (43%), Gaps = 2/152 (1%) Frame = +1 Query: 4 GTRVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKS 183 G RV I +CTN ++ A ++ G +V PW++ + P S V + + Sbjct: 281 GKRVDQVFIGTCTNGRIEDLRAAAEVLR------GRKVAPWVRLLVVPASSQVLEEAARD 334 Query: 184 GLQKYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHAL 363 G L + G I GC C+G + +V V + NRNF GR+ A Sbjct: 335 GTLLTLLEAGATIGTPGCGPCMGRH-------MGVLAPGEV---CVSTSNRNFRGRMGAP 384 Query: 364 TRANYLASPPLVVAYALAG--TVNIDFEKEPV 453 YLASP + A A+AG T + E+E V Sbjct: 385 DAEIYLASPRVAAASAVAGYLTTPEELEEEEV 416
>LEU2_LEPIN (Q8F4E6) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 465 Score = 52.8 bits (125), Expect = 1e-06 Identities = 40/131 (30%), Positives = 60/131 (45%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN+ ++ AA V G +V ++ + PGSG VK+ ++ GL K Sbjct: 343 IGSCTNSRIEDLRAAAATVK------GKKVSSKVQAIVVPGSGRVKRQAEQEGLDKIFTA 396 Query: 208 LGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLAS 387 GF GC+ C+ + D+ + D A+ + NRNFEGR R +L Sbjct: 397 AGFEWRNPGCSMCLAMNDDV-------LEPGDRCAS---TSNRNFEGRQGKGGR-THLVG 445 Query: 388 PPLVVAYALAG 420 P + A A+ G Sbjct: 446 PEMAAAAAIEG 456
>LEU2_LEPIC (Q72RC4) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 465 Score = 52.8 bits (125), Expect = 1e-06 Identities = 40/131 (30%), Positives = 60/131 (45%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN+ ++ AA V G +V ++ + PGSG VK+ ++ GL K Sbjct: 343 IGSCTNSRIEDLRAAAATVK------GKKVSSKVQAIVVPGSGRVKRQAEQEGLDKIFTA 396 Query: 208 LGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLAS 387 GF GC+ C+ + D+ + D A+ + NRNFEGR R +L Sbjct: 397 AGFEWRNPGCSMCLAMNDDV-------LEPGDRCAS---TSNRNFEGRQGKGGR-THLVG 445 Query: 388 PPLVVAYALAG 420 P + A A+ G Sbjct: 446 PEMAAAAAIEG 456
>LEU2_ECOLI (P0A6A6) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 465 Score = 52.8 bits (125), Expect = 1e-06 Identities = 45/132 (34%), Positives = 60/132 (45%), Gaps = 1/132 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN S + AA +AK G +V P ++ + PGSG VK + GL K + Sbjct: 343 IGSCTN-SRIEDLRAAAEIAK-----GRKVAPGVQALVVPGSGPVKAQAEAEGLDKIFIE 396 Query: 208 LGFNIVGYGCTTCIGNSGD-LDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 GF GC+ C+ + D L+ A T NRNFEGR R +L Sbjct: 397 AGFEWRLPGCSMCLAMNNDRLNPGERCAST-----------SNRNFEGRQGRGGR-THLV 444 Query: 385 SPPLVVAYALAG 420 SP + A A+ G Sbjct: 445 SPAMAAAAAVTG 456
>LEU2_ECOL6 (P0A6A7) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 465 Score = 52.8 bits (125), Expect = 1e-06 Identities = 45/132 (34%), Positives = 60/132 (45%), Gaps = 1/132 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN S + AA +AK G +V P ++ + PGSG VK + GL K + Sbjct: 343 IGSCTN-SRIEDLRAAAEIAK-----GRKVAPGVQALVVPGSGPVKAQAEAEGLDKIFIE 396 Query: 208 LGFNIVGYGCTTCIGNSGD-LDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 GF GC+ C+ + D L+ A T NRNFEGR R +L Sbjct: 397 AGFEWRLPGCSMCLAMNNDRLNPGERCAST-----------SNRNFEGRQGRGGR-THLV 444 Query: 385 SPPLVVAYALAG 420 SP + A A+ G Sbjct: 445 SPAMAAAAAVTG 456
>LEU2_ECO57 (Q8XA00) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 465 Score = 52.8 bits (125), Expect = 1e-06 Identities = 45/132 (34%), Positives = 60/132 (45%), Gaps = 1/132 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN S + AA +AK G +V P ++ + PGSG VK + GL K + Sbjct: 343 IGSCTN-SRIEDLRAAAEIAK-----GRKVAPGVQALVVPGSGPVKAQAEAEGLDKIFIE 396 Query: 208 LGFNIVGYGCTTCIGNSGD-LDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 GF GC+ C+ + D L+ A T NRNFEGR R +L Sbjct: 397 AGFEWRLPGCSMCLAMNNDRLNPGERCAST-----------SNRNFEGRQGRGGR-THLV 444 Query: 385 SPPLVVAYALAG 420 SP + A A+ G Sbjct: 445 SPAMAAAAAVTG 456
>LEU2_BORPE (Q7VY75) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 467 Score = 52.4 bits (124), Expect = 1e-06 Identities = 45/138 (32%), Positives = 64/138 (46%), Gaps = 1/138 (0%) Frame = +1 Query: 10 RVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGL 189 RV I SCTN+ + L AA V + + V+ + + PGSG+VK+ ++ GL Sbjct: 338 RVDRVFIGSCTNSRIED--LRAAAVVARGKRVAANVR---QAMVVPGSGLVKQQAEREGL 392 Query: 190 QKYLNQLGFNIVGYGCTTCIGNSGD-LDESVAAAITDNDVVAAAVLSGNRNFEGRVHALT 366 K + GF GC+ C+ + D L+ A T NRNFEGR Sbjct: 393 DKIFIEAGFEWREPGCSMCLAMNADRLEPGERCAST-----------SNRNFEGRQGQGG 441 Query: 367 RANYLASPPLVVAYALAG 420 R +L SP + A A+AG Sbjct: 442 R-THLVSPAMAAAAAVAG 458
>LEU2_BORPA (Q7W931) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 467 Score = 52.4 bits (124), Expect = 1e-06 Identities = 45/138 (32%), Positives = 64/138 (46%), Gaps = 1/138 (0%) Frame = +1 Query: 10 RVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGL 189 RV I SCTN+ + L AA V + + V+ + + PGSG+VK+ ++ GL Sbjct: 338 RVDRVFIGSCTNSRIED--LRAAAVVARGKRVAANVR---QAMVVPGSGLVKQQAEREGL 392 Query: 190 QKYLNQLGFNIVGYGCTTCIGNSGD-LDESVAAAITDNDVVAAAVLSGNRNFEGRVHALT 366 K + GF GC+ C+ + D L+ A T NRNFEGR Sbjct: 393 DKIFIEAGFEWREPGCSMCLAMNADRLEPGERCAST-----------SNRNFEGRQGQGG 441 Query: 367 RANYLASPPLVVAYALAG 420 R +L SP + A A+AG Sbjct: 442 R-THLVSPAMAAAAAVAG 458
>LEU2_BORBR (Q7WKH6) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 467 Score = 52.4 bits (124), Expect = 1e-06 Identities = 45/138 (32%), Positives = 64/138 (46%), Gaps = 1/138 (0%) Frame = +1 Query: 10 RVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGL 189 RV I SCTN+ + L AA V + + V+ + + PGSG+VK+ ++ GL Sbjct: 338 RVDRVFIGSCTNSRIED--LRAAAVVARGKRVAANVR---QAMVVPGSGLVKQQAEREGL 392 Query: 190 QKYLNQLGFNIVGYGCTTCIGNSGD-LDESVAAAITDNDVVAAAVLSGNRNFEGRVHALT 366 K + GF GC+ C+ + D L+ A T NRNFEGR Sbjct: 393 DKIFIEAGFEWREPGCSMCLAMNADRLEPGERCAST-----------SNRNFEGRQGQGG 441 Query: 367 RANYLASPPLVVAYALAG 420 R +L SP + A A+AG Sbjct: 442 R-THLVSPAMAAAAAVAG 458
>LEU2_LISMF (Q71Y33) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 462 Score = 52.4 bits (124), Expect = 1e-06 Identities = 47/143 (32%), Positives = 63/143 (44%), Gaps = 1/143 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN ++ A +V G +VK I+ + PGS V+ + GL K + Sbjct: 334 IGSCTNARLSDLEEAARIVK------GNKVKNNIRALVVPGSRQVRNAAESIGLDKIFIE 387 Query: 208 LGFNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 GF GC+ C+G N + + V A T NRNFEGR R +L Sbjct: 388 AGFEWREPGCSMCLGMNPDQVPDGVHCAST-----------SNRNFEGRQGKGAR-THLV 435 Query: 385 SPPLVVAYALAGTVNIDFEKEPV 453 SP + A A+ G ID KE V Sbjct: 436 SPAMAAAAAINGHF-IDIRKEAV 457
>LEU2_LISIN (Q92A26) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 462 Score = 52.4 bits (124), Expect = 1e-06 Identities = 47/143 (32%), Positives = 62/143 (43%), Gaps = 1/143 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN ++ A +V G +VK I+ + PGS V+ + GL K Sbjct: 334 IGSCTNARLSDLEEAARIVK------GNKVKNNIRALVVPGSRQVRNAAEAIGLDKIFKD 387 Query: 208 LGFNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 GF GC+ C+G N + + V A T NRNFEGR R +L Sbjct: 388 AGFEWREPGCSMCLGMNPDQVPDGVHCAST-----------SNRNFEGRQGKGAR-THLV 435 Query: 385 SPPLVVAYALAGTVNIDFEKEPV 453 SP + A A+ G ID KE V Sbjct: 436 SPAMAAAAAINGHF-IDIRKEAV 457
>ACON2_YEAST (P39533) Putative aconitase in PRP21-UBP12 intergenic region (EC| 4.2.1.3) Length = 789 Score = 52.4 bits (124), Expect = 1e-06 Identities = 48/170 (28%), Positives = 76/170 (44%), Gaps = 1/170 (0%) Frame = +1 Query: 10 RVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGL 189 +V I SCTN+S ++ LV K+A GL KP I + PGS ++ L++ G+ Sbjct: 376 KVSAGLIGSCTNSSYQDMSRVVDLV-KQASKAGL--KPRIPFFVTPGSEQIRATLERDGI 432 Query: 190 QKYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHA-LT 366 + G ++ C CIG D S + T+ S NRNF R Sbjct: 433 IDIFQENGAKVLANACGPCIGQWNREDVSKTSKETN-----TIFTSFNRNFRARNDGNRN 487 Query: 367 RANYLASPPLVVAYALAGTVNIDFEKEPVGISKDGKEVYFRDIWPSTDEI 516 N+L SP +V A + +G + + + + +GK+ F+ P DE+ Sbjct: 488 TMNFLTSPEIVTAMSYSGDAQFNPLTDSIKL-PNGKDFKFQP--PKGDEL 534
>LEU2_PSE14 (Q48K99) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 474 Score = 52.4 bits (124), Expect = 1e-06 Identities = 48/133 (36%), Positives = 63/133 (47%), Gaps = 2/133 (1%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLA-PGSGVVKKYLDKSGLQKYLN 204 I SCTN S + AA VAK G +V IK ++ PGSG++K+ +K GL K Sbjct: 349 IGSCTN-SRIEDLRAAADVAK-----GRKVAATIKQAIVVPGSGLIKEQAEKEGLDKVFI 402 Query: 205 QLGFNIVGYGCTTCIGNSGD-LDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYL 381 + GF GC+ C+ + D L A T NRNFEGR A R +L Sbjct: 403 EAGFEWREPGCSMCLAMNPDRLGSGEHCAST-----------SNRNFEGRQGAGGR-THL 450 Query: 382 ASPPLVVAYALAG 420 SP + A A+ G Sbjct: 451 VSPAMAAAAAVNG 463
>LEU2_THIDA (Q3SHL1) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 467 Score = 52.0 bits (123), Expect = 2e-06 Identities = 47/133 (35%), Positives = 61/133 (45%), Gaps = 2/133 (1%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLA-PGSGVVKKYLDKSGLQKYLN 204 I SCTN S + AA VAK G V P +K ++ PGSG+VK+ + GL + Sbjct: 345 IGSCTN-SRIEDLREAAAVAK-----GRRVAPNVKLAMVVPGSGLVKQQAEAEGLDRIFI 398 Query: 205 QLGFNIVGYGCTTCIGNSGD-LDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYL 381 GF GC+ C+ + D L+ A T NRNFEGR R +L Sbjct: 399 DAGFEWREPGCSMCLAMNADRLEPGERCAST-----------SNRNFEGRQGQGGR-THL 446 Query: 382 ASPPLVVAYALAG 420 SP + A A AG Sbjct: 447 VSPAMAAAAACAG 459
>LEU2_PASMU (Q9CJN7) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 467 Score = 52.0 bits (123), Expect = 2e-06 Identities = 42/131 (32%), Positives = 63/131 (48%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN S + AA +AK G +V ++ + PGSG+V++ +K GL K + Sbjct: 343 IGSCTN-SRIEDLRAAAAIAK-----GRKVADGVQALVVPGSGLVREQAEKEGLDKIFIE 396 Query: 208 LGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLAS 387 GF GC+ C+ + D + + A+ + NRNFEGR R +L S Sbjct: 397 AGFEWRLPGCSMCLAMNND-------RLAPGERCAS---TSNRNFEGRQGRGGR-THLVS 445 Query: 388 PPLVVAYALAG 420 P + A A+ G Sbjct: 446 PAMAAAAAVYG 456
>LEU2_BACCZ (Q63DX6) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 464 Score = 52.0 bits (123), Expect = 2e-06 Identities = 43/140 (30%), Positives = 66/140 (47%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN+ ++ + AA+V G +VK ++ + PGS V+ + GL + Sbjct: 334 IGSCTNSRLSDLEIAAAVVK------GRKVKEGVRALVVPGSKRVRDAAMQKGLHHIFEE 387 Query: 208 LGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLAS 387 GF GC+ C+G + D + + + A+ + NRNFEGR R +L S Sbjct: 388 AGFEWREPGCSMCLGMNPD-------QVPEGEHCAS---TSNRNFEGRQGKGAR-THLVS 436 Query: 388 PPLVVAYALAGTVNIDFEKE 447 P + A AL G +D KE Sbjct: 437 PAMAAAAALYGHF-VDTRKE 455
>LEU2_BUCDN (O85072) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 466 Score = 52.0 bits (123), Expect = 2e-06 Identities = 37/131 (28%), Positives = 62/131 (47%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN+ ++ + ++ ++ +K + PGSG+VK+ + GL K + Sbjct: 344 IGSCTNSRIEDLRSASKILKHN------KISKNVKAIVVPGSGLVKRQAESEGLDKIFIE 397 Query: 208 LGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLAS 387 GF GC+ C+G + D +++N+ A+ + NRNFEGR +L S Sbjct: 398 AGFEWRLPGCSMCLGMNND-------RLSENERCAS---TSNRNFEGR-QGRNGRTHLVS 446 Query: 388 PPLVVAYALAG 420 P + AL G Sbjct: 447 PIMAALAALYG 457
>LEU2_ACIAD (Q6FEW0) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 477 Score = 52.0 bits (123), Expect = 2e-06 Identities = 44/133 (33%), Positives = 62/133 (46%), Gaps = 2/133 (1%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSL-APGSGVVKKYLDKSGLQKYLN 204 I SCTN+ ++ A +V G +V IK ++ PGSG+VK+ ++ GL + Sbjct: 355 IGSCTNSRIEDIRAAAEVVK------GRKVASSIKQAMIVPGSGLVKQQAEQEGLDQVFL 408 Query: 205 QLGFNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYL 381 + GF GC+ C+ NS L A T NRNFEGR R +L Sbjct: 409 EAGFEWREPGCSMCLAMNSDKLQPGEHCAST-----------SNRNFEGRQGNGGR-THL 456 Query: 382 ASPPLVVAYALAG 420 SP + A A+AG Sbjct: 457 VSPAMAAAAAIAG 469
>LEU2_XANCP (P58949) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 479 Score = 52.0 bits (123), Expect = 2e-06 Identities = 49/133 (36%), Positives = 60/133 (45%), Gaps = 2/133 (1%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLA-PGSGVVKKYLDKSGLQKYLN 204 I SCTN S + AA VAK G +V IK +L PGSG+VK + GL K Sbjct: 350 IGSCTN-SRIEDLRAAAAVAK-----GRKVASTIKQALVVPGSGLVKAQAEAEGLDKIFL 403 Query: 205 QLGFNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYL 381 GF GC+ C+ N L A T NRNFEGR A R +L Sbjct: 404 DAGFEWREPGCSMCLAMNPDKLGSGEHCAST-----------SNRNFEGRQGAGGR-THL 451 Query: 382 ASPPLVVAYALAG 420 SP + A A++G Sbjct: 452 VSPAMAAAAAVSG 464
>LEU2_XANC8 (Q4UYG5) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 479 Score = 52.0 bits (123), Expect = 2e-06 Identities = 49/133 (36%), Positives = 60/133 (45%), Gaps = 2/133 (1%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLA-PGSGVVKKYLDKSGLQKYLN 204 I SCTN S + AA VAK G +V IK +L PGSG+VK + GL K Sbjct: 350 IGSCTN-SRIEDLRAAAAVAK-----GRKVASTIKQALVVPGSGLVKAQAEAEGLDKIFL 403 Query: 205 QLGFNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYL 381 GF GC+ C+ N L A T NRNFEGR A R +L Sbjct: 404 DAGFEWREPGCSMCLAMNPDKLGSGEHCAST-----------SNRNFEGRQGAGGR-THL 451 Query: 382 ASPPLVVAYALAG 420 SP + A A++G Sbjct: 452 VSPAMAAAAAVSG 464
>LEU2_XANAC (P58948) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 479 Score = 52.0 bits (123), Expect = 2e-06 Identities = 49/133 (36%), Positives = 60/133 (45%), Gaps = 2/133 (1%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLA-PGSGVVKKYLDKSGLQKYLN 204 I SCTN S + AA VAK G +V IK +L PGSG+VK + GL K Sbjct: 350 IGSCTN-SRIEDLRAAAAVAK-----GRKVASTIKQALVVPGSGLVKAQAEAEGLDKVFL 403 Query: 205 QLGFNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYL 381 GF GC+ C+ N L A T NRNFEGR A R +L Sbjct: 404 DAGFEWREPGCSMCLAMNPDKLGSGEHCAST-----------SNRNFEGRQGAGGR-THL 451 Query: 382 ASPPLVVAYALAG 420 SP + A A++G Sbjct: 452 VSPAMAAAAAVSG 464
>LEU2_XANOR (Q5H4D1) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 482 Score = 52.0 bits (123), Expect = 2e-06 Identities = 49/133 (36%), Positives = 60/133 (45%), Gaps = 2/133 (1%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLA-PGSGVVKKYLDKSGLQKYLN 204 I SCTN S + AA VAK G +V IK +L PGSG+VK + GL K Sbjct: 350 IGSCTN-SRIEDLRAAAAVAK-----GRKVASTIKQALVVPGSGLVKAQAEAEGLDKVFL 403 Query: 205 QLGFNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYL 381 GF GC+ C+ N L A T NRNFEGR A R +L Sbjct: 404 DAGFEWREPGCSMCLAMNPDKLGSGEHCAST-----------SNRNFEGRQGAGGR-THL 451 Query: 382 ASPPLVVAYALAG 420 SP + A A++G Sbjct: 452 VSPAMAAAAAVSG 464
>LEU2_XANC5 (Q3BPJ6) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 482 Score = 52.0 bits (123), Expect = 2e-06 Identities = 49/133 (36%), Positives = 60/133 (45%), Gaps = 2/133 (1%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLA-PGSGVVKKYLDKSGLQKYLN 204 I SCTN S + AA VAK G +V IK +L PGSG+VK + GL K Sbjct: 350 IGSCTN-SRIEDLRAAAAVAK-----GRKVASTIKQALVVPGSGLVKAQAEAEGLDKVFL 403 Query: 205 QLGFNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYL 381 GF GC+ C+ N L A T NRNFEGR A R +L Sbjct: 404 DAGFEWREPGCSMCLAMNPDKLGSGEHCAST-----------SNRNFEGRQGAGGR-THL 451 Query: 382 ASPPLVVAYALAG 420 SP + A A++G Sbjct: 452 VSPAMAAAAAVSG 464
>LEU2_BACC1 (Q73B98) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 464 Score = 51.6 bits (122), Expect = 2e-06 Identities = 42/140 (30%), Positives = 66/140 (47%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN+ ++ + A++V G +VK ++ + PGS V+ + GL + Sbjct: 334 IGSCTNSRLSDLEIAASVVK------GRKVKEGVRALVVPGSKRVRDAAMQKGLHHIFEE 387 Query: 208 LGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLAS 387 GF GC+ C+G + D + + + A+ + NRNFEGR R +L S Sbjct: 388 AGFEWREPGCSMCLGMNPD-------QVPEGEHCAS---TSNRNFEGRQGKGAR-THLVS 436 Query: 388 PPLVVAYALAGTVNIDFEKE 447 P + A AL G +D KE Sbjct: 437 PAMAAAAALYGHF-VDIRKE 455
>LEU2_BACAN (Q81T66) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 464 Score = 51.6 bits (122), Expect = 2e-06 Identities = 42/140 (30%), Positives = 66/140 (47%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN+ ++ + A++V G +VK ++ + PGS V+ + GL + Sbjct: 334 IGSCTNSRLSDLEIAASVVK------GRKVKEGVRALVVPGSKRVRDAAMQKGLHHIFEE 387 Query: 208 LGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLAS 387 GF GC+ C+G + D + + + A+ + NRNFEGR R +L S Sbjct: 388 AGFEWREPGCSMCLGMNPD-------QVPEGEHCAS---TSNRNFEGRQGKGAR-THLVS 436 Query: 388 PPLVVAYALAGTVNIDFEKE 447 P + A AL G +D KE Sbjct: 437 PAMAAAAALYGHF-VDIRKE 455
>LEU2_PSESM (Q884C2) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 475 Score = 51.6 bits (122), Expect = 2e-06 Identities = 48/133 (36%), Positives = 61/133 (45%), Gaps = 2/133 (1%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLA-PGSGVVKKYLDKSGLQKYLN 204 I SCTN S + AA VAK G +V IK ++ PGSG++K +K GL K Sbjct: 349 IGSCTN-SRIEDLRAAADVAK-----GRKVAATIKQAIVVPGSGLIKAQAEKEGLDKVFI 402 Query: 205 QLGFNIVGYGCTTCIGNSGD-LDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYL 381 GF GC+ C+ + D L A T NRNFEGR A R +L Sbjct: 403 DAGFEWREPGCSMCLAMNPDRLGSGEHCAST-----------SNRNFEGRQGAGGR-THL 450 Query: 382 ASPPLVVAYALAG 420 SP + A A+ G Sbjct: 451 VSPAMAAAAAVTG 463
>LEU2_DECAR (Q47HR4) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 468 Score = 51.6 bits (122), Expect = 2e-06 Identities = 44/133 (33%), Positives = 62/133 (46%), Gaps = 2/133 (1%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLA-PGSGVVKKYLDKSGLQKYLN 204 I SCTN+ ++ A+++ G V +K +LA PGSG+VK+ + GL K Sbjct: 345 IGSCTNSRIEDLREAASVLK------GRHVAANVKLALAVPGSGLVKRQAEAEGLDKVFV 398 Query: 205 QLGFNIVGYGCTTCIGNSGD-LDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYL 381 GF GC+ C+ + D L+ A T NRNFEGR R +L Sbjct: 399 AAGFEWREPGCSMCLAMNADRLEPGERCAST-----------SNRNFEGRQGPGGR-THL 446 Query: 382 ASPPLVVAYALAG 420 SP + A A+AG Sbjct: 447 VSPAMAAAAAIAG 459
>LEU22_BRAJA (Q89X34) 3-isopropylmalate dehydratase large subunit 2 (EC| 4.2.1.33) (Isopropylmalate isomerase 2) (Alpha-IPM isomerase 2) (IPMI 2) Length = 468 Score = 51.6 bits (122), Expect = 2e-06 Identities = 40/132 (30%), Positives = 55/132 (41%), Gaps = 1/132 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN ++ A + G +V + + PGSG+VK+ + GL K + Sbjct: 346 IGSCTNGRIEDLRAAAKIAE------GKQVSASVNAMVVPGSGIVKEQAEAEGLDKIFIK 399 Query: 208 LGFNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 GF GC+ C+ N L A T NRNFEGR +L Sbjct: 400 AGFEWREPGCSMCLAMNPDKLKPEERCAST-----------SNRNFEGR-QGFKGRTHLV 447 Query: 385 SPPLVVAYALAG 420 SP + A A+AG Sbjct: 448 SPAMAAAAAIAG 459
>LEU2_PROMM (Q7V4U5) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 478 Score = 51.6 bits (122), Expect = 2e-06 Identities = 43/141 (30%), Positives = 60/141 (42%) Frame = +1 Query: 4 GTRVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKS 183 G V + I SCTN + + AA +AK G V IK + PGS V + + Sbjct: 336 GVPVDVCFIGSCTN-GRLSDLKAAAAIAK-----GRHVAQGIKAFVVPGSEQVARAAEAE 389 Query: 184 GLQKYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHAL 363 GL + GF GC+ C+ + D E + + S NRNF+GR + Sbjct: 390 GLDGVFRKAGFEWREPGCSMCLAMNPDRLEGRQISAS----------SSNRNFKGRQGSS 439 Query: 364 TRANYLASPPLVVAYALAGTV 426 L SP +V A A+ G V Sbjct: 440 RGRTLLMSPAMVAAAAITGQV 460
>LEU2_PROMP (Q7V336) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 51.6 bits (122), Expect = 2e-06 Identities = 41/141 (29%), Positives = 63/141 (44%) Frame = +1 Query: 7 TRVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSG 186 T + + I SCTN ++ + A ++ +V IK + PGS V K + G Sbjct: 337 TPIDVCFIGSCTNGRISDLRVAAQVLEHN------KVAKNIKAFVVPGSEKVAKEAKEEG 390 Query: 187 LQKYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALT 366 L K + GF GC+ C+ + D + N V A+ S NRNF+GR + Sbjct: 391 LDKIFIKAGFQWREPGCSMCLAMNSD-------KLIGNQVSAS---SSNRNFKGRQGSPN 440 Query: 367 RANYLASPPLVVAYALAGTVN 429 L SP +V A ++ G V+ Sbjct: 441 GRTLLMSPAMVAAASITGKVS 461
>LEU2_PSEU2 (Q4ZUZ6) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 474 Score = 51.6 bits (122), Expect = 2e-06 Identities = 48/133 (36%), Positives = 62/133 (46%), Gaps = 2/133 (1%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLA-PGSGVVKKYLDKSGLQKYLN 204 I SCTN S + AA VAK G +V IK ++ PGSG++K +K GL K Sbjct: 349 IGSCTN-SRIEDLRAAADVAK-----GRKVASTIKQAIVVPGSGLIKAQAEKEGLDKVFI 402 Query: 205 QLGFNIVGYGCTTCIGNSGD-LDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYL 381 + GF GC+ C+ + D L A T NRNFEGR A R +L Sbjct: 403 EAGFEWREPGCSMCLAMNPDRLGSGEHCAST-----------SNRNFEGRQGAGGR-THL 450 Query: 382 ASPPLVVAYALAG 420 SP + A A+ G Sbjct: 451 VSPAMAAAAAVNG 463
>LEU2_PYRKO (Q5JFV6) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 380 Score = 51.2 bits (121), Expect = 3e-06 Identities = 42/141 (29%), Positives = 62/141 (43%) Frame = +1 Query: 4 GTRVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKS 183 GT++ I SCTN + A ++A G EV ++T + P S V + + ++ Sbjct: 251 GTKIDQVFIGSCTNGRFEQIERAAEILA------GEEVA--VRTIIGPASANVYRRMIET 302 Query: 184 GLQKYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHAL 363 G+ K L G I+ GC C+G D DV+ + NRNF GR+ + Sbjct: 303 GIAKVLIDAGAVILPPGCGPCLGRH-------MGVAGDGDVILSTT---NRNFRGRMGSP 352 Query: 364 TRANYLASPPLVVAYALAGTV 426 YLASP AL G + Sbjct: 353 NSEIYLASPVTAALSALYGEI 373
>LEU2_BLOPB (Q493R2) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 466 Score = 51.2 bits (121), Expect = 3e-06 Identities = 41/132 (31%), Positives = 59/132 (44%), Gaps = 1/132 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN+ ++ + A + G + + + PGS +VK +K GL K Q Sbjct: 344 IGSCTNSRIEDLRVAAQTIK------GHHISKNTQAIVVPGSKLVKNQAEKEGLNKIFIQ 397 Query: 208 LGFNIVGYGCTTCIGNSGD-LDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 GF GC+ C+ + D L+ A T NRNFEGR +R +L Sbjct: 398 AGFEWRLPGCSMCLAMNNDRLEPGERCAST-----------SNRNFEGRQGRGSR-THLV 445 Query: 385 SPPLVVAYALAG 420 SP + A A+AG Sbjct: 446 SPAMAAAAAIAG 457
>LEU2_NITWN (Q3SNV3) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 468 Score = 51.2 bits (121), Expect = 3e-06 Identities = 40/134 (29%), Positives = 57/134 (42%), Gaps = 3/134 (2%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN ++ A + G V + + PGSG+VK+ + GL K + Sbjct: 346 IGSCTNGRIEDLRAAAKIAE------GRTVNGNVSAMVVPGSGLVKEQAEAEGLDKIFTR 399 Query: 208 LGFNIVGYGCTTCIGNSGDL---DESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANY 378 GF GC+ C+ + D DE A+ + NRNFEGR + Sbjct: 400 AGFEWREPGCSMCLAMNPDKLKPDERCAS-------------TSNRNFEGR-QGFKGRTH 445 Query: 379 LASPPLVVAYALAG 420 L SP + A A+AG Sbjct: 446 LVSPSMAAAAAIAG 459
>LEU2_BACTN (Q8A6L7) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 464 Score = 50.8 bits (120), Expect = 4e-06 Identities = 44/144 (30%), Positives = 66/144 (45%), Gaps = 3/144 (2%) Frame = +1 Query: 4 GTRVVIAAITSCTNTSNPNVMLGAALV-AKKACDLGLEVKPWIKTSLAPGSGVVKKYLDK 180 G ++ + +CTN + A+LV ++ D V W L PGS +V + K Sbjct: 334 GKKIDYVFLGACTNGRIEDFRAFASLVKGRRKAD---NVIAW----LVPGSWMVDAQIRK 386 Query: 181 SGLQKYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAA--AVLSGNRNFEGRV 354 G+ K L + GF I GC+ C+ A+ D+ + A +V + NRNFEGR Sbjct: 387 EGIDKILTEAGFAIRQPGCSACL------------AMNDDKIPAGKYSVSTSNRNFEGRQ 434 Query: 355 HALTRANYLASPPLVVAYALAGTV 426 R LASP + A A+ G + Sbjct: 435 GPGAR-TLLASPLVAAAAAVTGVI 457
>LEU2_BACHK (Q6HLF1) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 464 Score = 50.8 bits (120), Expect = 4e-06 Identities = 42/140 (30%), Positives = 66/140 (47%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN+ ++ + A++V G +VK ++ + PGS V+ + GL + Sbjct: 334 IGSCTNSRLSDLEIAASVVK------GRKVKEGVRALVVPGSKRVRDAAIQKGLHHIFEE 387 Query: 208 LGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLAS 387 GF GC+ C+G + D + + + A+ + NRNFEGR R +L S Sbjct: 388 AGFEWREPGCSMCLGMNPD-------QVPEGEHCAS---TSNRNFEGRQGKGAR-THLVS 436 Query: 388 PPLVVAYALAGTVNIDFEKE 447 P + A AL G +D KE Sbjct: 437 PAMAAAAALYGHF-VDTRKE 455
>LEU2_STAS1 (Q49Z14) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 456 Score = 50.8 bits (120), Expect = 4e-06 Identities = 42/129 (32%), Positives = 59/129 (45%) Frame = +1 Query: 34 SCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQLG 213 SCTN +++ + +V G +V P I + PGS VK +K GL K G Sbjct: 335 SCTNARLSDLVEASHVVK------GNKVHPNITAIVVPGSRTVKIEAEKLGLDKIFKDAG 388 Query: 214 FNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLASPP 393 F+ GC+ C+G + D N V A+ + NRNFEGR R +L SP Sbjct: 389 FDWREPGCSMCLGMNPDQ--------VPNGVHCAS--TSNRNFEGRQGKGAR-THLVSPA 437 Query: 394 LVVAYALAG 420 + A A+ G Sbjct: 438 MAAAAAING 446
>LEU2_THET8 (Q9ZND5) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 472 Score = 50.8 bits (120), Expect = 4e-06 Identities = 38/141 (26%), Positives = 66/141 (46%) Frame = +1 Query: 4 GTRVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKS 183 G + +A I SCTN ++ A + G +VK ++ + PGS V + ++ Sbjct: 335 GVPIQVAFIGSCTNARLSDLREVARYLK------GHKVKKGVRALVVPGSEWVARKAEEE 388 Query: 184 GLQKYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHAL 363 G+ + + GF GC+ C+ + D + D + A+ S NRN++GR+ + Sbjct: 389 GIAEVFREAGFEWRMPGCSMCLAMNPDR--------LEGDELCAS--SSNRNYKGRMGSP 438 Query: 364 TRANYLASPPLVVAYALAGTV 426 L SP +V A A+AG + Sbjct: 439 RGRTVLMSPLMVAAAAVAGEI 459
>LEU2_THET2 (Q72JB3) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 472 Score = 50.8 bits (120), Expect = 4e-06 Identities = 38/141 (26%), Positives = 66/141 (46%) Frame = +1 Query: 4 GTRVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKS 183 G + +A I SCTN ++ A + G +VK ++ + PGS V + ++ Sbjct: 335 GVPIQVAFIGSCTNARLSDLREVARYLK------GHKVKKGVRALVVPGSEWVARKAEEE 388 Query: 184 GLQKYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHAL 363 G+ + + GF GC+ C+ + D + D + A+ S NRN++GR+ + Sbjct: 389 GIAEVFREAGFEWRMPGCSMCLAMNPDR--------LEGDELCAS--SSNRNYKGRMGSP 438 Query: 364 TRANYLASPPLVVAYALAGTV 426 L SP +V A A+AG + Sbjct: 439 RGRTVLMSPLMVAAAAVAGEI 459
>LEU2_BUCRP (P48573) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 471 Score = 50.8 bits (120), Expect = 4e-06 Identities = 42/133 (31%), Positives = 64/133 (48%), Gaps = 2/133 (1%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGV--VKKYLDKSGLQKYL 201 I SCTN+ ++ A ++ K ++ IK L PGSG VKK +K GL K Sbjct: 344 IGSCTNSRIEDLRSAAKILKNK------KISKNIKAILLPGSGTGTVKKPAEKEGLDKIF 397 Query: 202 NQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYL 381 GF GC+ C+G + D ++D + A+ + NRNFEGR R + + Sbjct: 398 IDAGFEWRLPGCSMCLGMNND-------KLSDGERCAS---TSNRNFEGRQGRGGRTHLV 447 Query: 382 ASPPLVVAYALAG 420 + P++ A A+ G Sbjct: 448 S--PIMAAAAIYG 458
>ACON_YEAST (P19414) Aconitate hydratase, mitochondrial precursor (EC 4.2.1.3)| (Citrate hydro-lyase) (Aconitase) Length = 778 Score = 50.8 bits (120), Expect = 4e-06 Identities = 45/156 (28%), Positives = 75/156 (48%), Gaps = 1/156 (0%) Frame = +1 Query: 13 VVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQ 192 V + I SCTN+S ++ A++V K A GL+ K ++ PGS ++ +++ G Sbjct: 374 VRVGLIGSCTNSSYEDMSRSASIV-KDAAAHGLKSKTIF--TVTPGSEQIRATIERDGQL 430 Query: 193 KYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRA 372 + + G ++ C CIG D D + + V S NRNF R + Sbjct: 431 ETFKEFGGIVLANACGPCIGQWDRRDIKKG----DKNTI---VSSYNRNFTSRNDGNPQT 483 Query: 373 N-YLASPPLVVAYALAGTVNIDFEKEPVGISKDGKE 477 + ++ASP LV A+A+AG + + + + KDG E Sbjct: 484 HAFVASPELVTAFAIAGDLRFNPLTDKLK-DKDGNE 518
>LEU2_PYRHO (O59391) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 380 Score = 50.4 bits (119), Expect = 5e-06 Identities = 42/141 (29%), Positives = 62/141 (43%) Frame = +1 Query: 4 GTRVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKS 183 GT++ I SCTN ++ A ++ G EV ++T + P S V K + + Sbjct: 251 GTKIDQVFIGSCTNGRFEHIKRAAEILK------GEEVA--VRTIIGPASVNVYKRMVRE 302 Query: 184 GLQKYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHAL 363 G+ L G I+ GC C+G + D +VV + NRNF GR+ + Sbjct: 303 GIVDILLDAGATILPPGCGPCLGRH-------MGVLGDKEVVLSTT---NRNFRGRMGSP 352 Query: 364 TRANYLASPPLVVAYALAGTV 426 T YLASP AL G + Sbjct: 353 TAEIYLASPLTAAVSALYGEI 373
>LEU2_PSEHT (Q3IJS4) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 466 Score = 50.4 bits (119), Expect = 5e-06 Identities = 40/131 (30%), Positives = 57/131 (43%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN+ ++ A +V K G+E + PGSG+VKK + GL Sbjct: 344 IGSCTNSRIEDLRAAAKIVEGKKVVAGIEAL------IVPGSGLVKKQAEDEGLADIFKA 397 Query: 208 LGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLAS 387 GF GC+ C+ + D+ + A + NRNFEGR R +L S Sbjct: 398 AGFEWREPGCSMCLAMN---DDRLGAG-------KRCASTSNRNFEGRQGRGGR-THLVS 446 Query: 388 PPLVVAYALAG 420 P + A A+ G Sbjct: 447 PAMAAAAAIHG 457
>LEU2_ERWCT (Q6D0G6) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 466 Score = 50.4 bits (119), Expect = 5e-06 Identities = 44/132 (33%), Positives = 59/132 (44%), Gaps = 1/132 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN S + AA +AK G +V ++ + PGSG VK + GL K + Sbjct: 344 IGSCTN-SRIEDLRAAAEIAK-----GRKVAAGVQAIVVPGSGPVKTMAELEGLDKVFIE 397 Query: 208 LGFNIVGYGCTTCIGNSGD-LDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 GF GC+ C+ + D L+ A T NRNFEGR R +L Sbjct: 398 AGFEWRLPGCSMCLAMNNDRLNPGERCAST-----------SNRNFEGRQGRAGR-THLV 445 Query: 385 SPPLVVAYALAG 420 SP + A A+ G Sbjct: 446 SPAMAAAAAVTG 457
>LEU2_PHOLL (Q7N127) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 50.4 bits (119), Expect = 5e-06 Identities = 41/132 (31%), Positives = 58/132 (43%), Gaps = 1/132 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN+ ++ AA+ G +V P ++ + PGSG V+ + GL K + Sbjct: 344 IGSCTNSRIEDLRAAAAIAQ------GHKVAPGVQAIVVPGSGPVQAQAEAEGLDKIFIE 397 Query: 208 LGFNIVGYGCTTCIGNSGD-LDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 GF GC+ C+ + D L A T NRNFEGR R +L Sbjct: 398 AGFEWRLPGCSMCLAMNNDRLQPGERCAST-----------SNRNFEGRQGRGGR-THLV 445 Query: 385 SPPLVVAYALAG 420 SP + A A+ G Sbjct: 446 SPAMAAAAAING 457
>LEU22_MANSM (Q65V07) 3-isopropylmalate dehydratase large subunit 2 (EC| 4.2.1.33) (Isopropylmalate isomerase 2) (Alpha-IPM isomerase 2) (IPMI 2) Length = 469 Score = 50.4 bits (119), Expect = 5e-06 Identities = 44/133 (33%), Positives = 61/133 (45%), Gaps = 2/133 (1%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALV-AKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLN 204 I SCTN+ ++ AA++ +K D VK + + PGSG+VK+ +K GL K Sbjct: 344 IGSCTNSRIEDLRAAAAVMKGRKKAD---NVK---RVLVVPGSGLVKEQAEKEGLDKIFL 397 Query: 205 QLGFNIVGYGCTTCIGNSGD-LDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYL 381 G GC+ C+G + D L E A T NRNFEGR +L Sbjct: 398 AAGAEWRNPGCSMCLGMNDDRLGEWERCAST-----------SNRNFEGR-QGRNGRTHL 445 Query: 382 ASPPLVVAYALAG 420 SP + A A+ G Sbjct: 446 VSPAMAAAAAVFG 458
>LEU2_SHEON (Q8E9N4) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 474 Score = 50.4 bits (119), Expect = 5e-06 Identities = 45/131 (34%), Positives = 61/131 (46%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN S + AA AK G +V + + PGSG VK + GL K + Sbjct: 352 IGSCTN-SRIEDLRSAAKHAK-----GRKVAAGVTAIVVPGSGQVKAQAEAEGLDKIFIE 405 Query: 208 LGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLAS 387 GF GC+ C+ + D E+ D A+ + NRNFEGR +R +L S Sbjct: 406 AGFEWRLPGCSMCLAMNDDRLEA-------GDRCAS---TSNRNFEGRQGRGSR-THLVS 454 Query: 388 PPLVVAYALAG 420 P + A A+AG Sbjct: 455 PAMAAAAAIAG 465
>LEU2_BUCBP (P59519) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 471 Score = 50.4 bits (119), Expect = 5e-06 Identities = 42/133 (31%), Positives = 59/133 (44%), Gaps = 2/133 (1%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVA-KKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLN 204 I SCTN+ ++ A +V K+ C+ + + PGSG+VK +K GL K Sbjct: 344 IGSCTNSRIEDLRAVAKIVMNKRVCNS-------VHAIIVPGSGMVKMQAEKEGLDKIFK 396 Query: 205 QLGFNIVGYGCTTCIGNSGD-LDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYL 381 GF GC+ C+ + D L+ A T NRNFEGR R +L Sbjct: 397 NSGFEWRYSGCSMCLAMNDDRLNNKERCAST-----------SNRNFEGRQGRGGR-THL 444 Query: 382 ASPPLVVAYALAG 420 SP + A A+ G Sbjct: 445 VSPVMAAAAAIFG 457
>LEU2_VIBCH (Q9KP81) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 467 Score = 50.1 bits (118), Expect = 7e-06 Identities = 44/132 (33%), Positives = 57/132 (43%), Gaps = 1/132 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 + SCTN S M AA VAK G +V ++ + PGS VK + GL K + Sbjct: 346 VGSCTN-SRIEDMRAAAAVAK-----GKKVASHVQALIVPGSEQVKAQAEAEGLDKIFIE 399 Query: 208 LGFNIVGYGCTTCIGNSGD-LDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 GF GC+ C+ + D L A T NRNFEGR +L Sbjct: 400 AGFEWRLPGCSMCLAMNNDRLGPGERCAST-----------SNRNFEGR-QGRDGRTHLV 447 Query: 385 SPPLVVAYALAG 420 SP + A A+AG Sbjct: 448 SPAMAAAAAIAG 459
>LEU2_SILPO (Q5LX06) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 468 Score = 50.1 bits (118), Expect = 7e-06 Identities = 38/131 (29%), Positives = 59/131 (45%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN ++ A +V G ++K ++ + PGSG+V+ ++ G+ L Sbjct: 346 IGSCTNGRIEDLRAVAEVVK------GKKIKSGLRAMVVPGSGLVRAQAEEEGIADILKD 399 Query: 208 LGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLAS 387 GF GC+ C+ + D + + AA + NRNFEGR +L S Sbjct: 400 AGFEWRLAGCSMCLAMNPD-------QLAPGERCAA---TSNRNFEGR-QGYKGRTHLVS 448 Query: 388 PPLVVAYALAG 420 P + A AL G Sbjct: 449 PAMAAAAALTG 459
>LEU2_STAAR (Q6GF14) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 455 Score = 50.1 bits (118), Expect = 7e-06 Identities = 41/125 (32%), Positives = 54/125 (43%), Gaps = 1/125 (0%) Frame = +1 Query: 34 SCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQLG 213 SCTN +++ + +V G +V P I + PGS VKK +K GL G Sbjct: 335 SCTNARLSDLIEASHIVK------GNKVHPNITAIVVPGSRTVKKEAEKLGLDTIFKNAG 388 Query: 214 FNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLASP 390 F GC+ C+G N + E V A T NRNFEGR R +L SP Sbjct: 389 FEWREPGCSMCLGMNPDQVPEGVHCAST-----------SNRNFEGRQGKGAR-THLVSP 436 Query: 391 PLVVA 405 + A Sbjct: 437 AMAAA 441
>LEU2_NEIG1 (Q5F8T1) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 50.1 bits (118), Expect = 7e-06 Identities = 43/138 (31%), Positives = 64/138 (46%), Gaps = 2/138 (1%) Frame = +1 Query: 13 VVIAAITSCTNTSNPNVMLGAALVA--KKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSG 186 V I I SCTN+ ++ AA+ KKA ++ + + PGSG+VK+ +K G Sbjct: 341 VDIVFIGSCTNSRIEDLREAAAIAKGHKKAGNVQ-------RVLIVPGSGLVKEQAEKEG 393 Query: 187 LQKYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALT 366 L K + GF GC+ C+ + D + A+ + NRNFEGR Sbjct: 394 LDKIFIEAGFEWREPGCSMCLAMNAD-------RLAPRQRCAS---TSNRNFEGRQGNGG 443 Query: 367 RANYLASPPLVVAYALAG 420 R +L SP + A A+ G Sbjct: 444 R-THLVSPAMAAAAAVTG 460
>LEU2_XYLFT (Q87BP9) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 474 Score = 50.1 bits (118), Expect = 7e-06 Identities = 42/133 (31%), Positives = 59/133 (44%), Gaps = 2/133 (1%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLA-PGSGVVKKYLDKSGLQKYLN 204 I SCTN+ ++ A +V G +V +K ++ PGSG+VK + GL K Sbjct: 350 IGSCTNSRIEDLRAAAEVVK------GRKVASTVKQAMVVPGSGLVKAQAEVEGLDKIFI 403 Query: 205 QLGFNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYL 381 + GF GC+ C+ N L A T NRNFEGR + +L Sbjct: 404 EAGFEWREPGCSMCLAMNPDKLGSGEHCAST-----------SNRNFEGR-QGIGGRTHL 451 Query: 382 ASPPLVVAYALAG 420 SP + A A+AG Sbjct: 452 VSPAMAAAAAVAG 464
>LEU2_XYLFA (Q9PAX0) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 474 Score = 50.1 bits (118), Expect = 7e-06 Identities = 42/133 (31%), Positives = 59/133 (44%), Gaps = 2/133 (1%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLA-PGSGVVKKYLDKSGLQKYLN 204 I SCTN+ ++ A +V G +V +K ++ PGSG+VK + GL K Sbjct: 350 IGSCTNSRIEDLRAAAEVVK------GRKVASTVKQAMVVPGSGLVKAQAEVEGLDKIFI 403 Query: 205 QLGFNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYL 381 + GF GC+ C+ N L A T NRNFEGR + +L Sbjct: 404 EAGFEWREPGCSMCLAMNPDKLGSGEHCAST-----------SNRNFEGR-QGIGGRTHL 451 Query: 382 ASPPLVVAYALAG 420 SP + A A+AG Sbjct: 452 VSPAMAAAAAVAG 464
>LEU2_AQUAE (O67078) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 432 Score = 50.1 bits (118), Expect = 7e-06 Identities = 40/136 (29%), Positives = 62/136 (45%), Gaps = 1/136 (0%) Frame = +1 Query: 22 AAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYL 201 A I SCTN ++ + AA V + A G +V P+++ + P S + K K GL Sbjct: 294 AFIGSCTNGRIEDLRV-AAKVFEAALKQGKKVHPYVRCIVIPASKAIYKQALKEGLIDIF 352 Query: 202 NQLGFNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANY 378 + G + C C+G + G L E + + NRNF GR+ +Y Sbjct: 353 MEAGCVVSTSTCGPCLGGHMGVLAEG-----------ERCISTSNRNFPGRMGHPKSESY 401 Query: 379 LASPPLVVAYALAGTV 426 LA+P +V A A+ G + Sbjct: 402 LANPAVVAASAIMGRI 417
>LEU2_PHOPR (Q6LV26) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 476 Score = 50.1 bits (118), Expect = 7e-06 Identities = 45/132 (34%), Positives = 57/132 (43%), Gaps = 1/132 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN S M AA +AK G +V ++ + PGS VK +K GL K + Sbjct: 350 IGSCTN-SRIEDMRAAAAIAK-----GRKVAANVQALVVPGSEQVKAQAEKEGLDKIFIE 403 Query: 208 LGFNIVGYGCTTCIGNSGD-LDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 GF GC+ C+ + D L A T NRNFEGR +L Sbjct: 404 AGFEWRLPGCSMCLAMNNDRLGPKERCAST-----------SNRNFEGR-QGRDGRTHLV 451 Query: 385 SPPLVVAYALAG 420 SP + A A AG Sbjct: 452 SPAMAAAAACAG 463
>LEU2_VIBF1 (Q5E858) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 471 Score = 50.1 bits (118), Expect = 7e-06 Identities = 41/131 (31%), Positives = 60/131 (45%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 + SCTN S M AA +AK G +V ++ + PGS VK +K GL + Sbjct: 346 VGSCTN-SRIEDMRAAAAIAK-----GRKVASHVQALIVPGSEQVKAQAEKEGLDVIFKE 399 Query: 208 LGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLAS 387 GF GC+ C+ + D + ++ A+ + NRNFEGR +L S Sbjct: 400 AGFEWRLPGCSMCLAMNND-------RLGPHERCAS---TSNRNFEGR-QGRDGRTHLVS 448 Query: 388 PPLVVAYALAG 420 P + A A+AG Sbjct: 449 PAMAAAAAIAG 459
>LEU2_LACLA (Q02142) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 460 Score = 50.1 bits (118), Expect = 7e-06 Identities = 42/132 (31%), Positives = 57/132 (43%), Gaps = 1/132 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN ++ A ++ + GL + PGS VK+ + GL K + Sbjct: 336 IGSCTNARLGDLEEAAKIIGDRHIADGLT------GIVVPGSRPVKEAAEAQGLDKIFKE 389 Query: 208 LGFNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 GF GC+ C+G N + E V A T NRNFEGR R +L Sbjct: 390 AGFEWREPGCSACLGMNPDQIPEYVHCAST-----------SNRNFEGRQGHNAR-THLC 437 Query: 385 SPPLVVAYALAG 420 SP + A A+AG Sbjct: 438 SPAMAAAAAIAG 449
>LEU22_SALTY (Q8ZRJ0) 3-isopropylmalate dehydratase large subunit 2 (EC| 4.2.1.33) (Isopropylmalate isomerase 2) (Alpha-IPM isomerase 2) (IPMI 2) Length = 473 Score = 49.7 bits (117), Expect = 9e-06 Identities = 40/137 (29%), Positives = 65/137 (47%) Frame = +1 Query: 10 RVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGL 189 R+ A I SCTN ++ A ++ G ++ ++ + PGS +V++ ++ GL Sbjct: 341 RISHAFIGSCTNGRIEDLRAVAKVLE------GRKIASHVRGIIVPGSTMVRRQAEEEGL 394 Query: 190 QKYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTR 369 K GF GC+ C+ + D+ ++ D A+ NRNF GR A R Sbjct: 395 AKIFIAAGFEWRQSGCSMCLAMNEDV-------LSPGDRCASGT---NRNFPGRQGAGAR 444 Query: 370 ANYLASPPLVVAYALAG 420 +L SP +V A A+AG Sbjct: 445 -THLMSPAMVAAAAVAG 460
>LEU2_RHOPA (Q6ND69) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 49.7 bits (117), Expect = 9e-06 Identities = 41/131 (31%), Positives = 60/131 (45%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN ++ AA VA+ G V + + PGSG+VK+ + GL K + Sbjct: 347 IGSCTNGRIEDLR-AAAKVAE-----GKTVNANVNAIIVPGSGLVKEQAEAEGLDKIFIK 400 Query: 208 LGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLAS 387 GF GC+ C+ + D + + A+ + NRNFEGR +L S Sbjct: 401 AGFEWREPGCSMCLAMNPD-------KLAPEERCAS---TSNRNFEGR-QGFKGRTHLVS 449 Query: 388 PPLVVAYALAG 420 P + A A+AG Sbjct: 450 PAMAAAAAIAG 460
>LEU2_AZOSE (Q5P1J8) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 49.7 bits (117), Expect = 9e-06 Identities = 47/133 (35%), Positives = 60/133 (45%), Gaps = 2/133 (1%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLA-PGSGVVKKYLDKSGLQKYLN 204 I SCTN S + AA VAK G P +K L PGSG+VK+ + GL + Sbjct: 346 IGSCTN-SRIEDLREAASVAK-----GRSKAPSVKRVLVVPGSGLVKRQAEAEGLHEVFL 399 Query: 205 QLGFNIVGYGCTTCIGNSGD-LDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYL 381 GF GC+ C+ + D L+ A T NRNFEGR A R +L Sbjct: 400 AAGFEWREPGCSMCLAMNADRLEPGEHCAST-----------SNRNFEGRQGAGGR-THL 447 Query: 382 ASPPLVVAYALAG 420 SP + A A+ G Sbjct: 448 VSPAMAAAAAVVG 460
>LEU2_YERPS (Q66EM3) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 476 Score = 49.7 bits (117), Expect = 9e-06 Identities = 41/132 (31%), Positives = 58/132 (43%), Gaps = 1/132 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN+ ++ AA+ G +V ++ + PGSG VK + GL K Sbjct: 350 IGSCTNSRIEDLRAAAAIAQ------GRKVAKGVQAIVVPGSGPVKAQAEAEGLDKIFIA 403 Query: 208 LGFNIVGYGCTTCIGNSGD-LDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 GF GC+ C+ + D L+ A T NRNFEGR R +L Sbjct: 404 AGFEWRLPGCSMCLAMNNDRLEPGERCAST-----------SNRNFEGRQGRGGR-THLV 451 Query: 385 SPPLVVAYALAG 420 SP + A A++G Sbjct: 452 SPAMAAAAAVSG 463
>LEU2_YERPE (Q8ZIH0) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 476 Score = 49.7 bits (117), Expect = 9e-06 Identities = 41/132 (31%), Positives = 58/132 (43%), Gaps = 1/132 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN+ ++ AA+ G +V ++ + PGSG VK + GL K Sbjct: 350 IGSCTNSRIEDLRAAAAIAQ------GRKVAKGVQAIVVPGSGPVKAQAEAEGLDKIFIA 403 Query: 208 LGFNIVGYGCTTCIGNSGD-LDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 GF GC+ C+ + D L+ A T NRNFEGR R +L Sbjct: 404 AGFEWRLPGCSMCLAMNNDRLEPGERCAST-----------SNRNFEGRQGRGGR-THLV 451 Query: 385 SPPLVVAYALAG 420 SP + A A++G Sbjct: 452 SPAMAAAAAVSG 463
>LEU2_RHOBA (Q7UIA7) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 485 Score = 49.7 bits (117), Expect = 9e-06 Identities = 38/131 (29%), Positives = 57/131 (43%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN ++ AA++ C + + PGSG VK ++ GL K Sbjct: 361 IGSCTNARIEDLRAAAAVIKGHHCS------DKVNAMIVPGSGKVKLQAEEEGLHKVFTD 414 Query: 208 LGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLAS 387 GF+ GC+ C+ + D + + A+ + NRNFEGR R +L S Sbjct: 415 AGFDWREAGCSMCLAMNPD-------KLAPGERCAS---TSNRNFEGRQGKGGR-THLVS 463 Query: 388 PPLVVAYALAG 420 P + A A+ G Sbjct: 464 PAMAAAAAIKG 474
>LEU2_LISMO (Q8Y5R7) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 462 Score = 49.7 bits (117), Expect = 9e-06 Identities = 46/143 (32%), Positives = 62/143 (43%), Gaps = 1/143 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN ++ A +V G +VK I+ + PGS V+ + GL K + Sbjct: 334 IGSCTNARLSDLEEAARIVK------GNKVKNNIRALVVPGSRQVRNAAESIGLDKIFIE 387 Query: 208 LGFNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 GF GC+ C+G N + + V A T NRNFEGR R +L Sbjct: 388 AGFEWREPGCSMCLGMNPDQVPDGVHCAST-----------SNRNFEGRQGKGAR-THLV 435 Query: 385 SPPLVVAYALAGTVNIDFEKEPV 453 SP + A A+ G ID K V Sbjct: 436 SPAMAAAAAINGHF-IDIRKVAV 457
>LEU2_BACFR (Q64QP1) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 464 Score = 49.3 bits (116), Expect = 1e-05 Identities = 43/143 (30%), Positives = 63/143 (44%), Gaps = 2/143 (1%) Frame = +1 Query: 4 GTRVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKS 183 G ++ + +CTN + A++V K V W L PGS +V + + Sbjct: 334 GKKIDYVFLGACTNGRIEDFRAFASIV--KGHQKAEHVIAW----LVPGSWMVDAQIREE 387 Query: 184 GLQKYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAA--AVLSGNRNFEGRVH 357 GL K L GF I GC+ C+ A+ D+ + A +V + NRNFEGR Sbjct: 388 GLDKILEDAGFAIRQPGCSACL------------AMNDDKIPAGKYSVSTSNRNFEGRQG 435 Query: 358 ALTRANYLASPPLVVAYALAGTV 426 R LASP + A A+ G + Sbjct: 436 PGAR-TLLASPLVAAAAAITGVI 457
>LEU2_BACFN (Q5LAB1) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 464 Score = 49.3 bits (116), Expect = 1e-05 Identities = 43/143 (30%), Positives = 63/143 (44%), Gaps = 2/143 (1%) Frame = +1 Query: 4 GTRVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKS 183 G ++ + +CTN + A++V K V W L PGS +V + + Sbjct: 334 GKKIDYVFLGACTNGRIEDFRAFASIV--KGHQKAEHVIAW----LVPGSWMVDAQIREE 387 Query: 184 GLQKYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAA--AVLSGNRNFEGRVH 357 GL K L GF I GC+ C+ A+ D+ + A +V + NRNFEGR Sbjct: 388 GLDKILEDAGFAIRQPGCSACL------------AMNDDKIPAGKYSVSTSNRNFEGRQG 435 Query: 358 ALTRANYLASPPLVVAYALAGTV 426 R LASP + A A+ G + Sbjct: 436 PGAR-TLLASPLVAAAAAITGVI 457
>LEU2_PROMA (Q7VDT0) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 468 Score = 49.3 bits (116), Expect = 1e-05 Identities = 38/141 (26%), Positives = 61/141 (43%) Frame = +1 Query: 4 GTRVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKS 183 G + + I SCTN ++ A + + +V +K + PGS V + + Sbjct: 336 GIPIDVCFIGSCTNGRLSDLEKAAEIAKNR------QVAKGVKAFVVPGSEKVAQDAESQ 389 Query: 184 GLQKYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHAL 363 GL + GF GC+ C+ + D E N + A+ S NRNF+GR + Sbjct: 390 GLDTIFEKAGFEWRKPGCSMCLAMNPDKLER-------NQISAS---SSNRNFKGRQGSA 439 Query: 364 TRANYLASPPLVVAYALAGTV 426 L SP +V A A+ G++ Sbjct: 440 QGRTLLMSPAMVAAAAVTGSI 460
>LEU2_RALEU (Q44023) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) (Fragment) Length = 267 Score = 49.3 bits (116), Expect = 1e-05 Identities = 40/135 (29%), Positives = 57/135 (42%) Frame = +1 Query: 22 AAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYL 201 A I SCTN+ ++ A ++A G +V P + P S VK+ + GL + Sbjct: 141 AFIGSCTNSRLSDLRSAAGVLA------GRKVAPGVTAICVPVSSAVKRAAEAEGLDRVF 194 Query: 202 NQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYL 381 + GF GC+ C G+ I+ S NRNFE R TR +L Sbjct: 195 REAGFEWRESGCSMCFYAGGESFGHRQRVIS----------STNRNFESRQGPQTR-THL 243 Query: 382 ASPPLVVAYALAGTV 426 A P V A A+ G + Sbjct: 244 AGPATVAASAVLGRI 258
>LEU22_SALCH (Q57SN1) 3-isopropylmalate dehydratase large subunit 2 (EC| 4.2.1.33) (Isopropylmalate isomerase 2) (Alpha-IPM isomerase 2) (IPMI 2) Length = 473 Score = 48.9 bits (115), Expect = 1e-05 Identities = 40/137 (29%), Positives = 65/137 (47%) Frame = +1 Query: 10 RVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGL 189 R+ A I SCTN ++ A ++ G ++ ++ + PGS +V++ ++ GL Sbjct: 341 RISHAFIGSCTNGRIEDLRAVAKVLE------GRKIASHVRGIIVPGSTMVRRQAEEEGL 394 Query: 190 QKYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTR 369 K GF GC+ C+ + D+ ++ D A+ NRNF GR A R Sbjct: 395 AKIFIAAGFEWRQSGCSMCLAMNEDV-------LSPGDRCASGT---NRNFLGRQGAGAR 444 Query: 370 ANYLASPPLVVAYALAG 420 +L SP +V A A+AG Sbjct: 445 -THLMSPAMVAAAAVAG 460
>LEU2_VIBPA (Q87SS9) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 471 Score = 48.9 bits (115), Expect = 1e-05 Identities = 41/131 (31%), Positives = 60/131 (45%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 + SCTN S M AA+VAK G +V ++ + PGS VK + GL + Sbjct: 344 VGSCTN-SRIEDMRAAAVVAK-----GRKVASHVQALIVPGSEQVKAQAEAEGLDVIFKE 397 Query: 208 LGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLAS 387 GF GC+ C+ + D + ++ A+ + NRNFEGR +L S Sbjct: 398 AGFEWRLPGCSMCLAMNND-------RLGPHERCAS---TSNRNFEGR-QGRDGRTHLVS 446 Query: 388 PPLVVAYALAG 420 P + A A+AG Sbjct: 447 PAMAAAAAIAG 457
>LEU2_HAEI8 (Q4QLS2) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 48.9 bits (115), Expect = 1e-05 Identities = 43/133 (32%), Positives = 60/133 (45%), Gaps = 2/133 (1%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALV-AKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLN 204 I SCTN+ ++ AA++ +K D VK + + PGSG+VK+ +K GL K Sbjct: 344 IGSCTNSRIEDLRAAAAVMKGRKKAD---NVK---RILVVPGSGLVKEQAEKEGLDKIFI 397 Query: 205 QLGFNIVGYGCTTCIGNSGD-LDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYL 381 G GC+ C+G + D L E A T NRNFEGR +L Sbjct: 398 AAGAEWRNPGCSMCLGMNDDRLGEWERCAST-----------SNRNFEGR-QGRNGRTHL 445 Query: 382 ASPPLVVAYALAG 420 SP + A + G Sbjct: 446 VSPAMAAAAGMFG 458
>LEU2_BACLD (Q65GJ0) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 472 Score = 48.9 bits (115), Expect = 1e-05 Identities = 37/131 (28%), Positives = 60/131 (45%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN+ ++ A ++ G +V ++ + PGS VK +K GL K + Sbjct: 344 IGSCTNSRMTDLRQAAEMIK------GQKVADGVRAIVVPGSQSVKIQAEKEGLHKIFIE 397 Query: 208 LGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLAS 387 GF GC+ C+ + D+ + + + A+ + NRNFEGR R +L S Sbjct: 398 AGFEWRESGCSMCLSMNNDV-------VPEGERCAS---TSNRNFEGRQGKGAR-THLVS 446 Query: 388 PPLVVAYALAG 420 P + A+ G Sbjct: 447 PAMAAMAAIHG 457
>LEU2_VIBVY (Q7MP79) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 466 Score = 48.9 bits (115), Expect = 1e-05 Identities = 41/131 (31%), Positives = 60/131 (45%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 + SCTN S M AA+VAK G +V ++ + PGS VK + GL + Sbjct: 344 VGSCTN-SRIEDMRAAAVVAK-----GRKVASHVQALIVPGSEQVKAQAEAEGLDVIFKE 397 Query: 208 LGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLAS 387 GF GC+ C+ + D + ++ A+ + NRNFEGR +L S Sbjct: 398 AGFEWRLPGCSMCLAMNND-------RLGPHERCAS---TSNRNFEGR-QGRDGRTHLVS 446 Query: 388 PPLVVAYALAG 420 P + A A+AG Sbjct: 447 PAMAAAAAIAG 457
>LEU2_VIBVU (Q8DED9) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 466 Score = 48.9 bits (115), Expect = 1e-05 Identities = 41/131 (31%), Positives = 60/131 (45%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 + SCTN S M AA+VAK G +V ++ + PGS VK + GL + Sbjct: 344 VGSCTN-SRIEDMRAAAVVAK-----GRKVASHVQALIVPGSEQVKAQAEAEGLDVIFKE 397 Query: 208 LGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLAS 387 GF GC+ C+ + D + ++ A+ + NRNFEGR +L S Sbjct: 398 AGFEWRLPGCSMCLAMNND-------RLGPHERCAS---TSNRNFEGR-QGRDGRTHLVS 446 Query: 388 PPLVVAYALAG 420 P + A A+AG Sbjct: 447 PAMAAAAAIAG 457
>LEU2_METCA (Q606F2) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 470 Score = 48.9 bits (115), Expect = 1e-05 Identities = 43/139 (30%), Positives = 61/139 (43%), Gaps = 2/139 (1%) Frame = +1 Query: 10 RVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLA-PGSGVVKKYLDKSG 186 RV I SCTN ++ A +V G + +K +L PGSG+VK+ ++ G Sbjct: 339 RVDRVFIGSCTNARIEDLRAAAEVVR------GHKRAASVKQALVVPGSGLVKRQAEQEG 392 Query: 187 LQKYLNQLGFNIVGYGCTTCIGNSGD-LDESVAAAITDNDVVAAAVLSGNRNFEGRVHAL 363 L K + GF GC+ C+ + D L+ A T NRNFEGR Sbjct: 393 LDKVFLEAGFEWRDPGCSMCLAMNADRLEPGERCAST-----------SNRNFEGR-QGY 440 Query: 364 TRANYLASPPLVVAYALAG 420 +L SP + A A+ G Sbjct: 441 GGRTHLVSPAMAAAAAIHG 459
>LEU2_HAEIN (P44968) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 468 Score = 48.5 bits (114), Expect = 2e-05 Identities = 43/133 (32%), Positives = 60/133 (45%), Gaps = 2/133 (1%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALV-AKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLN 204 I SCTN+ ++ AA++ +K D VK + + PGSG+VK+ +K GL K Sbjct: 343 IGSCTNSRIEDLRAAAAVMKGRKKAD---NVK---RILVVPGSGLVKEQAEKEGLDKIFI 396 Query: 205 QLGFNIVGYGCTTCIGNSGD-LDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYL 381 G GC+ C+G + D L E A T NRNFEGR +L Sbjct: 397 AAGAEWRNPGCSMCLGMNDDRLGEWERCAST-----------SNRNFEGR-QGRNGRTHL 444 Query: 382 ASPPLVVAYALAG 420 SP + A + G Sbjct: 445 VSPAMAAAAGVFG 457
>LYS4_YEAST (P49367) Homoaconitase, mitochondrial precursor (EC 4.2.1.36)| (Homoaconitate hydratase) Length = 693 Score = 48.5 bits (114), Expect = 2e-05 Identities = 41/138 (29%), Positives = 64/138 (46%), Gaps = 2/138 (1%) Frame = +1 Query: 22 AAITSCTNTSNPNVMLGAALVAKKACDLGL--EVKPWIKTSLAPGSGVVKKYLDKSGLQK 195 A + SCTN+ ++ A +V DL +V P ++ +A S ++ KSG + Sbjct: 335 AYLVSCTNSRLSDLQSAADVVCPTG-DLNKVNKVAPGVEFYVAAASSEIEADARKSGAWE 393 Query: 196 YLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRAN 375 L + G + GC CIG L E I+ + NRNF+GR+ + Sbjct: 394 KLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGIS----------ATNRNFKGRMGSKDALA 443 Query: 376 YLASPPLVVAYALAGTVN 429 YLASP +V A A+ G ++ Sbjct: 444 YLASPAVVAASAVLGKIS 461
>LEU2_PROMT (Q46HB8) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 48.5 bits (114), Expect = 2e-05 Identities = 40/141 (28%), Positives = 59/141 (41%) Frame = +1 Query: 4 GTRVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKS 183 G + + I SCTN ++ + +V G V I+ + PGS V K + Sbjct: 336 GQSIDVCFIGSCTNGRLSDLEEASKIVK------GNTVADGIRAFVVPGSQKVAKEAKEK 389 Query: 184 GLQKYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHAL 363 GL K + GF GC+ C+ + D E + + S NRNF+GR + Sbjct: 390 GLDKIFLKAGFEWREPGCSMCLAMNPDKLEGRQISAS----------SSNRNFKGRQGSA 439 Query: 364 TRANYLASPPLVVAYALAGTV 426 L SP +V A A+ G V Sbjct: 440 NGRTLLMSPAMVAAAAINGKV 460
>LEU2_CHRVO (Q7NUB6) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 471 Score = 48.5 bits (114), Expect = 2e-05 Identities = 46/136 (33%), Positives = 62/136 (45%) Frame = +1 Query: 13 VVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQ 192 V + I SCTN S + AA VAK G VK + + PGSG+VK + GL Sbjct: 341 VDVVFIGSCTN-SRIEDLREAAAVAKGRSKAG-NVK---QVLVVPGSGLVKAQAEAEGLD 395 Query: 193 KYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRA 372 K GF GC+ C+ + D + + A+ + NRNFEGR R Sbjct: 396 KIFVAAGFEWREPGCSMCLAMNAD-------RLLPGERCAS---TSNRNFEGRQGQGGR- 444 Query: 373 NYLASPPLVVAYALAG 420 +L SP + A A+AG Sbjct: 445 THLVSPAMAAAAAVAG 460
>LEU2_BUCAI (P56934) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 471 Score = 48.5 bits (114), Expect = 2e-05 Identities = 39/131 (29%), Positives = 60/131 (45%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN ++ + ++ K ++ +K + PGSG VK+ + GL K Sbjct: 344 IGSCTNGRIEDLRAASKILKDK------KIANNVKAIVVPGSGSVKREAENEGLDKIFIS 397 Query: 208 LGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLAS 387 GF GC+ C+G + D + D + A+ + NRNFEGR R +L S Sbjct: 398 AGFEWRLPGCSMCLGMNKD-------RLNDGERCAS---TSNRNFEGRQGRGGR-THLVS 446 Query: 388 PPLVVAYALAG 420 P + A A+ G Sbjct: 447 PIMAAAAAVYG 457
>LEU2_BIFLO (Q8G4W2) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 467 Score = 48.1 bits (113), Expect = 3e-05 Identities = 39/136 (28%), Positives = 64/136 (47%), Gaps = 2/136 (1%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVA--KKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYL 201 I SCTN ++ AA++ +KA ++ + + P S V+ +K GL K Sbjct: 345 IGSCTNGRIDDLRQAAAIMKGHRKAENIH-------RVLVVPASSRVRLQAEKEGLDKVF 397 Query: 202 NQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYL 381 G GC+ C+G + D + N+ ++ + NRNFEGR +R +L Sbjct: 398 KDFGAEWRNAGCSMCLGMNPD-------KLVPNE---RSISTSNRNFEGRQGKGSR-THL 446 Query: 382 ASPPLVVAYALAGTVN 429 ASP + A A+ GT++ Sbjct: 447 ASPAVAAATAIRGTIS 462
>LEU22_PYRAB (Q9V1J0) 3-isopropylmalate dehydratase large subunit 2 (EC| 4.2.1.33) (Isopropylmalate isomerase 2) (Alpha-IPM isomerase 2) (IPMI 2) Length = 380 Score = 48.1 bits (113), Expect = 3e-05 Identities = 39/141 (27%), Positives = 61/141 (43%) Frame = +1 Query: 4 GTRVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKS 183 GT++ I SCTN + A ++ + + ++T +AP S V + + + Sbjct: 251 GTKIDQVFIGSCTNGRFEQIKRAAEILDGEQVN--------VRTLVAPASINVYRRMIEE 302 Query: 184 GLQKYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHAL 363 GL + L G I+ GC C+G DN+V+ + NRNF GR+ + Sbjct: 303 GLVRILIDAGVVILPPGCGPCLGRH-------MGVAGDNEVILSTT---NRNFRGRMGSP 352 Query: 364 TRANYLASPPLVVAYALAGTV 426 YLASP AL G + Sbjct: 353 KAEIYLASPVTAAVSALYGEI 373
>LEU2_BUCUO (Q9EVI0) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) (Fragment) Length = 443 Score = 47.4 bits (111), Expect = 4e-05 Identities = 34/111 (30%), Positives = 49/111 (44%), Gaps = 3/111 (2%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN ++ + ++ K ++ +K + PGSG+VKK +K GL K Sbjct: 344 IGSCTNARIEDLRSASVILKNK------KIANHVKAIVVPGSGLVKKQAEKEGLDKIFID 397 Query: 208 LGFNIVGYGCTTCIGNSGD---LDESVAAAITDNDVVAAAVLSGNRNFEGR 351 GF GC+ C+G + D E A+ NRNFEGR Sbjct: 398 SGFEWRLPGCSMCLGMNKDRLNFQERCAS-------------HSNRNFEGR 435
>LEU2_BUCPS (P58945) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 465 Score = 47.0 bits (110), Expect = 6e-05 Identities = 40/132 (30%), Positives = 54/132 (40%), Gaps = 1/132 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN+ ++ A +V V + + PGSG+VK ++ GL K Sbjct: 344 IGSCTNSRTEDLRAAANIVQNT------HVAKNVHAIVVPGSGMVKLQAEEEGLDKIFIN 397 Query: 208 LGFNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 GF GC+ C+G N L A T NRNFEGR +L Sbjct: 398 AGFEWRLPGCSMCLGMNLDRLKPKERCAST-----------SNRNFEGR-QGRDGRTHLV 445 Query: 385 SPPLVVAYALAG 420 SP + A A+ G Sbjct: 446 SPAMAAAAAIFG 457
>LEU2_ZYMMO (Q5NRC5) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 484 Score = 47.0 bits (110), Expect = 6e-05 Identities = 45/151 (29%), Positives = 64/151 (42%), Gaps = 1/151 (0%) Frame = +1 Query: 4 GTRVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLA-PGSGVVKKYLDK 180 G V I SCTN+ ++ A++V G V +K +L PGSG+VK+ + Sbjct: 345 GLAVENVFIGSCTNSRIEDLRAAASVV------WGRHVADNVKQALVVPGSGLVKRQAEA 398 Query: 181 SGLQKYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHA 360 GL + GF GC+ C+ + D V A + NRNF GR Sbjct: 399 EGLDEVFKAAGFEWREPGCSMCLAMNPD---KVPAG-------ERCASTSNRNFVGRQGP 448 Query: 361 LTRANYLASPPLVVAYALAGTVNIDFEKEPV 453 R +L SP + A A+ G + EPV Sbjct: 449 GAR-THLVSPAMAAAAAVTGHLTDLRHLEPV 478
>LEU2_BACSU (P80858) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) (Superoxide-inducible protein 10) (SOI10) Length = 472 Score = 47.0 bits (110), Expect = 6e-05 Identities = 36/131 (27%), Positives = 60/131 (45%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN+ ++ A ++ G +V ++ + PGS VK +K GL + + Sbjct: 344 IGSCTNSRMTDLRQAADMIK------GKKVADSVRAIVVPGSQSVKLQAEKEGLDQIFLE 397 Query: 208 LGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLAS 387 GF GC+ C+ + D+ + + + A+ + NRNFEGR R +L S Sbjct: 398 AGFEWRESGCSMCLSMNNDV-------VPEGERCAS---TSNRNFEGRQGKGAR-THLVS 446 Query: 388 PPLVVAYALAG 420 P + A+ G Sbjct: 447 PAMAAMAAIHG 457
>LEU2_PELUB (Q4FP15) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 467 Score = 47.0 bits (110), Expect = 6e-05 Identities = 39/135 (28%), Positives = 60/135 (44%), Gaps = 1/135 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN ++ A ++ K + ++ + PGSG+VK+ ++ GL K Sbjct: 344 IGSCTNGRIEDLREAAKILKDK------KKASHVQAMVVPGSGLVKEQAEQEGLDKIFIA 397 Query: 208 LGFNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 GF GC+ C+ N+ L A T NRNFEGR R +L Sbjct: 398 SGFEWREPGCSMCLAMNADKLKPGERCAST-----------SNRNFEGRQGRGGR-THLV 445 Query: 385 SPPLVVAYALAGTVN 429 SP + A A++G ++ Sbjct: 446 SPGMAAAAAISGNLD 460
>LEU2_BLOFL (Q7VQJ8) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 466 Score = 46.6 bits (109), Expect = 7e-05 Identities = 39/132 (29%), Positives = 56/132 (42%), Gaps = 1/132 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN+ ++ A ++ ++ + + PGS VKK +K GL + Sbjct: 344 IGSCTNSRIEDLRSAANIIKDH------KISNNVHAIVVPGSKPVKKQAEKEGLDSIFIK 397 Query: 208 LGFNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 GF GC+ C+G N L+ A T NRNFEGR +L Sbjct: 398 AGFEWRLPGCSMCLGMNEDRLNAGERCAST-----------SNRNFEGR-QGRGGLTHLV 445 Query: 385 SPPLVVAYALAG 420 SP + A A+AG Sbjct: 446 SPAMAAAAAIAG 457
>LEU2_CORDI (Q6NHL0) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 480 Score = 46.6 bits (109), Expect = 7e-05 Identities = 35/131 (26%), Positives = 60/131 (45%) Frame = +1 Query: 34 SCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQLG 213 SCTN ++ + A ++ G + ++ + P S ++K+ + GL K + G Sbjct: 360 SCTNARMDDLRIAADILR------GRSIADSVRMMVVPSSTMIKEQAEAEGLDKIFIEAG 413 Query: 214 FNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLASPP 393 GC+ C+G + D +T + A+ + NRNFEGR R +L SP Sbjct: 414 AQWRTAGCSMCLGMNPD-------QLTPGERCAS---TSNRNFEGRQGPGGR-THLVSPA 462 Query: 394 LVVAYALAGTV 426 + A A+ GT+ Sbjct: 463 VAAATAIKGTL 473
>LEU2_CAMJR (Q5HS78) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 468 Score = 46.2 bits (108), Expect = 1e-04 Identities = 37/141 (26%), Positives = 59/141 (41%) Frame = +1 Query: 4 GTRVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKS 183 G ++ I I SCTN ++ + A ++ G ++ +K + PGS V+K + Sbjct: 336 GVKIDIVFIGSCTNGRLEDLKIAADILK------GRKIHKNVKALIVPGSMQVRKEAENL 389 Query: 184 GLQKYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHAL 363 GL K + G GC+ C+G + D S + + NRNF GR Sbjct: 390 GLDKIFIEAGCEWRYAGCSMCLGMNDDKANSGQRVAS----------TSNRNFVGR-QGK 438 Query: 364 TRANYLASPPLVVAYALAGTV 426 +L SP A A+ G + Sbjct: 439 GSITHLMSPASAAACAIEGVI 459
>LEU2_CAMJE (Q9PLW1) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 470 Score = 46.2 bits (108), Expect = 1e-04 Identities = 37/141 (26%), Positives = 59/141 (41%) Frame = +1 Query: 4 GTRVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKS 183 G ++ I I SCTN ++ + A ++ G ++ +K + PGS V+K + Sbjct: 338 GVKIDIVFIGSCTNGRLEDLKIAADILK------GRKIHKNVKALIVPGSMQVRKEAENL 391 Query: 184 GLQKYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHAL 363 GL K + G GC+ C+G + D S + + NRNF GR Sbjct: 392 GLDKIFIEAGCEWRYAGCSMCLGMNDDKANSGQRVAS----------TSNRNFVGR-QGK 440 Query: 364 TRANYLASPPLVVAYALAGTV 426 +L SP A A+ G + Sbjct: 441 GSITHLMSPASAAACAIEGVI 461
>LEU22_PYRFU (Q8U0C0) 3-isopropylmalate dehydratase large subunit 2 (EC| 4.2.1.33) (Isopropylmalate isomerase 2) (Alpha-IPM isomerase 2) (IPMI 2) Length = 380 Score = 45.8 bits (107), Expect = 1e-04 Identities = 38/141 (26%), Positives = 61/141 (43%) Frame = +1 Query: 4 GTRVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKS 183 GT++ I SCTN G KA ++ K ++T + P S V K + + Sbjct: 251 GTKIDQVFIGSCTN--------GRFEQISKAAEILEGEKVAVRTIVGPASMNVYKRMIEE 302 Query: 184 GLQKYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHAL 363 G+ + L + G I+ GC C+G + D ++V + NRNF GR+ + Sbjct: 303 GVARKLIEAGAVILPPGCGPCLGRH-------MGVVGDGEIVLSTT---NRNFRGRMGSP 352 Query: 364 TRANYLASPPLVVAYALAGTV 426 YL++P AL G + Sbjct: 353 NAQIYLSNPITAAVSALYGEI 373
>ACON_SCHPO (O13966) Aconitate hydratase, mitochondrial precursor (EC 4.2.1.3)| (Citrate hydro-lyase) (Aconitase) Length = 778 Score = 45.4 bits (106), Expect = 2e-04 Identities = 35/132 (26%), Positives = 56/132 (42%), Gaps = 24/132 (18%) Frame = +1 Query: 19 IAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKY 198 + I SCTN+S + M AA + ++A D G++ K ++ PGS V+ L + G Sbjct: 375 VGLIGSCTNSSYED-MSRAASICQQAIDKGIKTKSLF--TITPGSEQVRATLTRDGQLDT 431 Query: 199 LNQLGFNIVGYGCTTCIGN------------------------SGDLDESVAAAITDNDV 306 + + G ++ C CIG D + + A +T D+ Sbjct: 432 MRKAGGIVLANACGPCIGQWKRTDVKKGEKNSIVTSYNRNFTGRNDANPATHAFVTSPDI 491 Query: 307 VAAAVLSGNRNF 342 V A V SG+ NF Sbjct: 492 VTAMVFSGDMNF 503
>LEU2_WOLSU (Q7M9Z9) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 422 Score = 45.4 bits (106), Expect = 2e-04 Identities = 38/135 (28%), Positives = 59/135 (43%) Frame = +1 Query: 22 AAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYL 201 A I SCTN ++ + A ++ G V P ++ + PG+ + K + GL L Sbjct: 298 AFIGSCTNGRLSDLRIAAQILK------GKRVHPDVRLIITPGTQQIYKDAHQEGLIDTL 351 Query: 202 NQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYL 381 + G I C C+G + DN+ V + NRNF GR+ A + YL Sbjct: 352 LEAGALISNPTCGACLGG-------YMGILGDNE---RCVSTTNRNFVGRMGARSSEVYL 401 Query: 382 ASPPLVVAYALAGTV 426 A+ + A AL G + Sbjct: 402 ANSAVAAASALKGKI 416
>LEU2_BUCUE (Q9EVH4) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) (Fragment) Length = 443 Score = 45.4 bits (106), Expect = 2e-04 Identities = 33/111 (29%), Positives = 48/111 (43%), Gaps = 3/111 (2%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN ++ + ++ K ++ +K + PGSG VK+ +K GL K Sbjct: 344 IGSCTNARIEDLRSASKILKNK------KISKNVKAIVVPGSGSVKEQAEKEGLDKIFIN 397 Query: 208 LGFNIVGYGCTTCIGNSGD---LDESVAAAITDNDVVAAAVLSGNRNFEGR 351 GF GC+ C+G + D E A+ NRNFEGR Sbjct: 398 AGFEWRLPGCSMCLGMNNDRLNFGERCAS-------------XSNRNFEGR 435
>LYS4_CANGA (Q6FM51) Homoaconitase, mitochondrial precursor (EC 4.2.1.36)| (Homoaconitate hydratase) Length = 689 Score = 45.1 bits (105), Expect = 2e-04 Identities = 39/137 (28%), Positives = 60/137 (43%), Gaps = 2/137 (1%) Frame = +1 Query: 22 AAITSCTNTSNPNVMLGAALVAKKACDLGL--EVKPWIKTSLAPGSGVVKKYLDKSGLQK 195 A + SCTN ++ A +V DL +V ++ A S ++K + G+ + Sbjct: 331 AYLVSCTNARLSDLESAAKVVCPTG-DLSKVNKVADGVEFYFAAASSEIEKEAAEKGIWQ 389 Query: 196 YLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRAN 375 L G + GC CIG L E I+ + NRNF+GR+ + Sbjct: 390 ALLAAGCKPLPSGCGPCIGLGAGLLEPGEVGIS----------ATNRNFKGRMGSKDALA 439 Query: 376 YLASPPLVVAYALAGTV 426 YLASP +V A A+ G + Sbjct: 440 YLASPAVVAASAVLGRI 456
>LEU22_THEMA (Q9WZ24) 3-isopropylmalate dehydratase large subunit 2 (EC| 4.2.1.33) (Isopropylmalate isomerase 2) (Alpha-IPM isomerase 2) (IPMI 2) Length = 417 Score = 45.1 bits (105), Expect = 2e-04 Identities = 38/135 (28%), Positives = 57/135 (42%) Frame = +1 Query: 22 AAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYL 201 A I SCTN ++ L A ++ G V P ++ + PGS V K K GL Sbjct: 293 AVIGSCTNGRIEDLRLAAQILK------GRTVSPDVRCIIIPGSQKVYKQALKEGLIDIF 346 Query: 202 NQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYL 381 G + C C+G + + +V A+ + NRNF GR+ +L Sbjct: 347 IDAGCAVSTPTCGPCLGGH-------MGVLAEGEV---AISTTNRNFVGRMGHPNSKVFL 396 Query: 382 ASPPLVVAYALAGTV 426 ASP + A A+ G + Sbjct: 397 ASPAVAAASAIKGYI 411
>LEU2_PSYAR (Q4FRU7) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 472 Score = 45.1 bits (105), Expect = 2e-04 Identities = 43/133 (32%), Positives = 58/133 (43%), Gaps = 2/133 (1%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLA-PGSGVVKKYLDKSGLQKYLN 204 I SCTN+ ++ AA++ G +V IK ++ GSG VK + GL Sbjct: 350 IGSCTNSRIEDLRDAAAVIK------GRKVADNIKEAIVVAGSGQVKLQAEAEGLDALFT 403 Query: 205 QLGFNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYL 381 GF GC+ C+ N+ L+ A T NRNFEGR R +L Sbjct: 404 DAGFEWREPGCSMCLAMNADKLEPQEHCAST-----------SNRNFEGRQGNGGR-THL 451 Query: 382 ASPPLVVAYALAG 420 SP + A ALAG Sbjct: 452 VSPAMAAAAALAG 464
>LEU21_MANSM (Q65VS0) 3-isopropylmalate dehydratase large subunit 1 (EC| 4.2.1.33) (Isopropylmalate isomerase 1) (Alpha-IPM isomerase 1) (IPMI 1) Length = 475 Score = 45.1 bits (105), Expect = 2e-04 Identities = 39/133 (29%), Positives = 61/133 (45%) Frame = +1 Query: 22 AAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYL 201 A I SCTN ++ A ++ G ++ ++ + PGS V+ + GL K Sbjct: 348 AFIGSCTNGRIEDLREVAKVLK------GRKIAQGVRGMIIPGSTQVRARAEAEGLAKIF 401 Query: 202 NQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYL 381 GF GC+ C+ + D+ ++ D A+ NRNF GR A +R +L Sbjct: 402 IDAGFEWRQSGCSMCLAMNEDV-------LSPGDRCASGT---NRNFAGRQGAGSR-THL 450 Query: 382 ASPPLVVAYALAG 420 SP +V A A+AG Sbjct: 451 MSPAMVAAAAVAG 463
>LEU2_ACTTI (Q44427) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 485 Score = 43.9 bits (102), Expect = 5e-04 Identities = 39/137 (28%), Positives = 57/137 (41%), Gaps = 1/137 (0%) Frame = +1 Query: 13 VVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQ 192 V + + SCTN ++ A ++ G +V ++ + PGS V++ + GL Sbjct: 359 VDVVFVGSCTNGRLEDLRAAADVIR------GRKVADGVRMMIVPGSYQVREQAEAEGLD 412 Query: 193 KYLNQLGFNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTR 369 K G GC+ C+G N L AA T NRNFEGR R Sbjct: 413 KIFIDAGAEWRFAGCSMCLGMNPDTLSPGQRAAST-----------SNRNFEGRQGKGGR 461 Query: 370 ANYLASPPLVVAYALAG 420 +L SP + A A+ G Sbjct: 462 -THLVSPQVAAATAVVG 477
>LEU2_BUCUN (Q9EVI6) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) (Fragment) Length = 443 Score = 43.9 bits (102), Expect = 5e-04 Identities = 32/111 (28%), Positives = 48/111 (43%), Gaps = 3/111 (2%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN ++ A ++ K ++ ++ + PGSG VK+ ++ GL K Sbjct: 344 IGSCTNARIEDLRSAAGILKNK------KIAKHVQAIVVPGSGSVKRQAEREGLDKIFID 397 Query: 208 LGFNIVGYGCTTCIGNSGD---LDESVAAAITDNDVVAAAVLSGNRNFEGR 351 GF GC+ C+G + D E A+ NRNFEGR Sbjct: 398 SGFEWRLPGCSMCLGMNKDRLNFGERCAS-------------XSNRNFEGR 435
>LEU21_PYRFU (Q8U2A1) 3-isopropylmalate dehydratase large subunit 1 (EC| 4.2.1.33) (Isopropylmalate isomerase 1) (Alpha-IPM isomerase 1) (IPMI 1) Length = 424 Score = 43.9 bits (102), Expect = 5e-04 Identities = 37/133 (27%), Positives = 56/133 (42%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN ++ + A ++ G +V PW++ + P S V K GL + + Sbjct: 300 IGSCTNGRLEDLRMAAEVLE------GQKVAPWVRLIILPCSPTVYFKAMKEGLLEIFLE 353 Query: 208 LGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLAS 387 G I C C+G + S A++ NRNF GR+ YLAS Sbjct: 354 AGAVIGPPTCGPCLGGHMGILASGERAVSTT----------NRNFVGRMGHPKSEVYLAS 403 Query: 388 PPLVVAYALAGTV 426 P + A A+ G + Sbjct: 404 PYVAAASAILGRI 416
>LEU2_LEIXX (Q6AFK7) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 486 Score = 43.9 bits (102), Expect = 5e-04 Identities = 35/138 (25%), Positives = 64/138 (46%) Frame = +1 Query: 34 SCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQLG 213 SCTN+ ++ A+++ G + ++ + PGS V+ + G+ K + + G Sbjct: 352 SCTNSRIEDLRAFASVIK------GRKKAEGVRVMVVPGSARVRLEAEAEGIDKIVEEFG 405 Query: 214 FNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLASPP 393 GC+ C+G + D + + A+ + NRNFEGR R +L SP Sbjct: 406 AEWRFAGCSMCLGMNPD-------QLAPGERCAS---TSNRNFEGRQGKGGR-THLVSPL 454 Query: 394 LVVAYALAGTVNIDFEKE 447 + A A+ GT++ ++ E Sbjct: 455 VAAATAIRGTLSSPWDLE 472
>LEU2_MYCTU (O53237) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 473 Score = 43.9 bits (102), Expect = 5e-04 Identities = 37/134 (27%), Positives = 61/134 (45%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 + SCTN ++ + A ++ G +V ++ + PGS V+ + GL + Sbjct: 351 VGSCTNGRIEDLRVVAEVLR------GRKVADGVRMLIVPGSMRVRAQAEAEGLGEIFTD 404 Query: 208 LGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLAS 387 G GC+ C+G + D + + AA + NRNFEGR A R +L S Sbjct: 405 AGAQWRQAGCSMCLGMNPD-------QLASGERCAA---TSNRNFEGRQGAGGR-THLVS 453 Query: 388 PPLVVAYALAGTVN 429 P + A A+ GT++ Sbjct: 454 PAVAAATAVRGTLS 467
>LEU2_MYCBO (Q7TXH6) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 473 Score = 43.9 bits (102), Expect = 5e-04 Identities = 37/134 (27%), Positives = 61/134 (45%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 + SCTN ++ + A ++ G +V ++ + PGS V+ + GL + Sbjct: 351 VGSCTNGRIEDLRVVAEVLR------GRKVADGVRMLIVPGSMRVRAQAEAEGLGEIFTD 404 Query: 208 LGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLAS 387 G GC+ C+G + D + + AA + NRNFEGR A R +L S Sbjct: 405 AGAQWRQAGCSMCLGMNPD-------QLASGERCAA---TSNRNFEGRQGAGGR-THLVS 453 Query: 388 PPLVVAYALAGTVN 429 P + A A+ GT++ Sbjct: 454 PAVAAATAVRGTLS 467
>LYS4_EMENI (Q92412) Homoaconitase, mitochondrial precursor (EC 4.2.1.36)| (Homoaconitate hydratase) Length = 775 Score = 43.9 bits (102), Expect = 5e-04 Identities = 56/216 (25%), Positives = 89/216 (41%), Gaps = 8/216 (3%) Frame = +1 Query: 22 AAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWI---KTSLAPGSGVVKKYLDKSGLQ 192 A + SCTN S + + AA V K+A + P I K +A S + + +G Sbjct: 389 AYLVSCTN-SRASDIAAAAKVFKEAAEKNGGKIPKIHGVKFYIAAASIPEQLAAEGNGDW 447 Query: 193 KYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRA 372 + L + G + GC CIG L E I+ + NRNF+GR+ + Sbjct: 448 QTLLEAGATQLPAGCGPCIGMGQGLLEPGEVGIS----------ASNRNFKGRMGSTEAK 497 Query: 373 NYLASPPLVVAYALAGTVN-IDFEKEPVG----ISKDGKEVYFRDIWPSTDEIAEVVKSS 537 YL SP +V A AL+G ++ + + P G I +G + D + +E E + Sbjct: 498 AYLGSPEVVAASALSGKLSGPGWYQTPEGWTEVIRGEGDGIREEDRMLTNEEALEKIIGQ 557 Query: 538 VLPDMFKGTYEAITKGNPMWNELPVSASTLYPWDPK 645 L D+ + P E + +YP P+ Sbjct: 558 -LDDLVADGEKRFASETPAVEESEQGLTEIYPGFPE 592
>LEU2_BUCUH (Q9EVH7) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) (Fragment) Length = 442 Score = 43.5 bits (101), Expect = 6e-04 Identities = 29/108 (26%), Positives = 47/108 (43%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN ++ + ++ + ++ +K + PGSG VK+ ++ GL K Sbjct: 344 IGSCTNARIEDLRSASKILKNR------KISSNVKAIVVPGSGSVKQQAEREGLDKIFIN 397 Query: 208 LGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGR 351 GF GC+ C+G + D ++ NRNFEGR Sbjct: 398 SGFEWRLPGCSMCLGMNRD----------QLNIGERCASXSNRNFEGR 435
>LEU2_MYCPA (Q73VI7) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 476 Score = 43.5 bits (101), Expect = 6e-04 Identities = 37/134 (27%), Positives = 61/134 (45%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 + SCTN ++ + A ++ G +V P ++ + PGS V+ + GL + Sbjct: 354 VGSCTNGRIEDLRVVADVLR------GRKVAPGVRMLVVPGSMRVRAQAEAEGLGEVFTA 407 Query: 208 LGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLAS 387 G GC+ C+G + D + + AA + NRNFEGR R +L S Sbjct: 408 AGAEWRQAGCSMCLGMNPD-------QLAPGERCAA---TSNRNFEGRQGKGGR-THLVS 456 Query: 388 PPLVVAYALAGTVN 429 P + A A+ GT++ Sbjct: 457 PAVAAATAVRGTLS 470
>LEU2_BUCUM (Q9EVG8) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) (Fragment) Length = 444 Score = 43.5 bits (101), Expect = 6e-04 Identities = 32/109 (29%), Positives = 48/109 (44%), Gaps = 1/109 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN ++ + ++ + ++ +K + PGSG VK+ ++ GL K Sbjct: 345 IGSCTNARIEDLRAASKILKNR------KIAKHVKAIVVPGSGSVKRKAEQEGLDKIFID 398 Query: 208 LGFNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGR 351 GF GC+ C+G N L+ A T NRNFEGR Sbjct: 399 SGFEWRLPGCSMCLGMNKDRLNFGERCAST-----------SNRNFEGR 436
>LEU2_PICTO (Q6L0K5) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 413 Score = 43.5 bits (101), Expect = 6e-04 Identities = 39/140 (27%), Positives = 54/140 (38%), Gaps = 1/140 (0%) Frame = +1 Query: 10 RVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGL 189 R+ A I SCTN ++ A ++ K D ++ + P S V K GL Sbjct: 284 RIDQAYIGSCTNGRIEDIRRAALILKDKKIDKN------VRLMVVPASQEVYNQALKEGL 337 Query: 190 QKYLNQLGFNIVGYGCTTCIGN-SGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALT 366 + G G C C+G G L T N RNF GR+ T Sbjct: 338 VDIITDAGGYFAGTTCGACLGGYMGVLGPGETCISTTN-----------RNFIGRMGDRT 386 Query: 367 RANYLASPPLVVAYALAGTV 426 YLA+P +V A A+ G + Sbjct: 387 SRVYLANPEVVAASAIMGRI 406
>LEU2_BUCTS (O31293) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 466 Score = 43.5 bits (101), Expect = 6e-04 Identities = 39/132 (29%), Positives = 55/132 (41%), Gaps = 1/132 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN+ ++ + + ++ K +V K + PGS +VK +K GL K Sbjct: 344 IGSCTNSRIEDLRIASKIIKNK------KVAKTTKAIVVPGSKLVKIQAEKEGLDKIFIN 397 Query: 208 LGFNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 GF GC+ C+ N L+ A T NRNFE R R +L Sbjct: 398 AGFEWRLPGCSMCLAMNDDKLNRGERCAST-----------SNRNFEDRQGRGGR-THLV 445 Query: 385 SPPLVVAYALAG 420 SP A A+ G Sbjct: 446 SPITAAAAAIFG 457
>LEU21_METMA (Q8PZT3) 3-isopropylmalate dehydratase large subunit 1 (EC| 4.2.1.33) (Isopropylmalate isomerase 1) (Alpha-IPM isomerase 1) (IPMI 1) Length = 391 Score = 43.1 bits (100), Expect = 8e-04 Identities = 40/142 (28%), Positives = 60/142 (42%), Gaps = 1/142 (0%) Frame = +1 Query: 4 GTRVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKS 183 GT V I +CTN ++ + A+++ K K ++T + P S K+ Sbjct: 264 GTHVDQVFIGTCTNGRLEDLEVAASVLKGK--------KVTVRTIIIPASRSTLLAAIKN 315 Query: 184 GLQKYLNQLGFNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHA 360 G + L + G + GC C+G + G L E V + NRNF+GR+ Sbjct: 316 GTMEILLKAGVTLATPGCGPCLGAHQGVLGEG-----------EVCVSTANRNFKGRM-G 363 Query: 361 LTRANYLASPPLVVAYALAGTV 426 YLASP A AL G + Sbjct: 364 KDGFIYLASPATAAASALTGEI 385
>LEU2_CORGL (P58946) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 481 Score = 43.1 bits (100), Expect = 8e-04 Identities = 36/133 (27%), Positives = 57/133 (42%), Gaps = 1/133 (0%) Frame = +1 Query: 34 SCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQLG 213 SCTN ++ + A ++ G ++ ++ + P S +K+ + GL K G Sbjct: 362 SCTNARIEDLQIAADILK------GHKIADGMRMMVVPSSTWIKQEAEALGLDKIFTDAG 415 Query: 214 FNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLASP 390 GC+ C+G N L +A T NRNFEGR R +L SP Sbjct: 416 AEWRTAGCSMCLGMNPDQLKPGERSAST-----------SNRNFEGRQGPGGR-THLVSP 463 Query: 391 PLVVAYALAGTVN 429 + A A+ GT++ Sbjct: 464 AVAAATAIRGTLS 476
>LEU2_COREF (Q8FPR3) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 481 Score = 43.1 bits (100), Expect = 8e-04 Identities = 38/133 (28%), Positives = 58/133 (43%), Gaps = 1/133 (0%) Frame = +1 Query: 34 SCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQLG 213 SCTN ++ + A ++ G ++ I+ + P S VK+ +K GL K + G Sbjct: 362 SCTNARIEDLEIAAEILK------GRKIADDIRMMVVPSSTWVKQEAEKLGLDKIFIEAG 415 Query: 214 FNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLASP 390 GC+ C+G N L +A T NRNFEGR R +L SP Sbjct: 416 AEWRTAGCSMCLGMNPDQLKPGERSAST-----------SNRNFEGRQGPGGR-THLVSP 463 Query: 391 PLVVAYALAGTVN 429 + A A+ G ++ Sbjct: 464 AVAAATAVRGKLS 476
>LEU2_NOCFA (Q5YRY0) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 474 Score = 43.1 bits (100), Expect = 8e-04 Identities = 38/135 (28%), Positives = 57/135 (42%), Gaps = 1/135 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 + SCTN ++ A ++ G V ++ + PGS V+ +K GL + Sbjct: 352 VGSCTNGRIEDLRAAAEILK------GRRVAEGVRMLVVPGSMRVRAQAEKEGLGEIFTA 405 Query: 208 LGFNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 G GC+ C+G N L+ A T NRNFEGR R +L Sbjct: 406 AGAEWRQAGCSMCLGMNPDQLEPGQRCAST-----------SNRNFEGRQGKGGR-THLV 453 Query: 385 SPPLVVAYALAGTVN 429 SP + A A+ GT++ Sbjct: 454 SPLVAAATAVRGTLS 468
>LEU22_ARCFU (O28084) 3-isopropylmalate dehydratase large subunit 2 (EC| 4.2.1.33) (Isopropylmalate isomerase 2) (Alpha-IPM isomerase 2) (IPMI 2) Length = 416 Score = 42.7 bits (99), Expect = 0.001 Identities = 40/142 (28%), Positives = 67/142 (47%), Gaps = 1/142 (0%) Frame = +1 Query: 4 GTRVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSG-VVKKYLDK 180 GT V I +CTN ++ + A ++ G +VK ++ + P S V + LDK Sbjct: 285 GTEVNQVYIGTCTNGRLSDLEVAARILK------GRKVKEGVRLIVVPASRRVYLQALDK 338 Query: 181 SGLQKYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHA 360 GL + + G ++ GC C+G + + + A D +V + + NRNF+GR+ Sbjct: 339 -GLIRVFVEAGGMVLNPGCGPCVG----IHQGILA---DGEV---CISTQNRNFKGRMGN 387 Query: 361 LTRANYLASPPLVVAYALAGTV 426 +LASP A A+ G + Sbjct: 388 PNAEIFLASPATAAASAVKGYI 409
>LEU2_BUCUL (Q9AQC6) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) (Fragment) Length = 369 Score = 42.4 bits (98), Expect = 0.001 Identities = 30/108 (27%), Positives = 46/108 (42%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN ++ + ++ + ++ +K + PGSG VK+ + GL K Sbjct: 271 IGSCTNARIEDLRSASTILKNR------KIANNVKAIVVPGSGSVKQQAEMEGLDKIFIN 324 Query: 208 LGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGR 351 GF GC+ C+G + D +V NRNFEGR Sbjct: 325 AGFEWRLPGCSMCLGMNND----------RLNVGERCASHSNRNFEGR 362
>LEU2_BUCML (Q9EVG2) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) (Fragment) Length = 442 Score = 42.4 bits (98), Expect = 0.001 Identities = 31/108 (28%), Positives = 47/108 (43%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I S TN ++ L A ++ K ++ ++ + PGSG VK+ ++ GL K Sbjct: 344 IGSXTNARIEDLRLAAKILKNK------KISNNVQAIVVPGSGSVKRQAEREGLDKIFIN 397 Query: 208 LGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGR 351 GF GC+ C+G + D +V NRNFEGR Sbjct: 398 AGFEWRLPGCSMCLGMNRD----------RLNVGERCASXSNRNFEGR 435
>LEU22_METKA (Q8TW29) 3-isopropylmalate dehydratase large subunit 2 (EC| 4.2.1.33) (Isopropylmalate isomerase 2) (Alpha-IPM isomerase 2) (IPMI 2) Length = 402 Score = 42.4 bits (98), Expect = 0.001 Identities = 37/139 (26%), Positives = 58/139 (41%) Frame = +1 Query: 4 GTRVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKS 183 G V + SCTN +V + ++ + P ++ + P S V + + ++ Sbjct: 269 GVEVTRVFVGSCTNGRYRDVRVFTEILEELDGP-----HPDVRIVVVPASRRVLERMTEA 323 Query: 184 GLQKYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHAL 363 GL L ++G I GC C+G + D+DV V + NRNF GR+ + Sbjct: 324 GLTLKLIRMGVMIAPPGCGPCLGEH-------LGVLGDDDV---CVSTANRNFPGRMGSR 373 Query: 364 TRANYLASPPLVVAYALAG 420 YLASP A G Sbjct: 374 RAEIYLASPVTAAVAAAEG 392
>LEU2_BUCUA (Q9EVG5) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) (Fragment) Length = 443 Score = 42.0 bits (97), Expect = 0.002 Identities = 32/111 (28%), Positives = 47/111 (42%), Gaps = 3/111 (2%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN ++ + ++ K +V + + PGSG+VK ++ GL K Sbjct: 344 IGSCTNARIEDLRSASKILKNK------KVAKHVTAIVVPGSGLVKNQAEEEGLDKIFID 397 Query: 208 LGFNIVGYGCTTCIGNSGD---LDESVAAAITDNDVVAAAVLSGNRNFEGR 351 GF GC+ C+G + D E A+ NRNFEGR Sbjct: 398 AGFEWRLPGCSMCLGMNKDRLNFGERCAS-------------HSNRNFEGR 435
>LEU2_CLOAB (Q97EE0) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 422 Score = 41.2 bits (95), Expect = 0.003 Identities = 37/134 (27%), Positives = 59/134 (44%), Gaps = 1/134 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN ++ + A+++ G ++K I+ + PG+ + + GL + + Sbjct: 299 IGSCTNGRMEDLRIAASILK------GKKIKKGIRLIVFPGTQNIYLEAMEEGLVRTFIE 352 Query: 208 LGFNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 G + C C+G + G L E A T N RNF GR+ YLA Sbjct: 353 AGGIVSTPTCGPCLGGHMGILAEGERAISTTN-----------RNFVGRMGHPKSEVYLA 401 Query: 385 SPPLVVAYALAGTV 426 SP + A A+AG + Sbjct: 402 SPAVAAASAIAGKI 415
>LEU21_METKA (Q8TVF2) 3-isopropylmalate dehydratase large subunit 1 (EC| 4.2.1.33) (Isopropylmalate isomerase 1) (Alpha-IPM isomerase 1) (IPMI 1) Length = 418 Score = 41.2 bits (95), Expect = 0.003 Identities = 38/134 (28%), Positives = 56/134 (41%), Gaps = 1/134 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN ++ + A ++ G EV ++ + P S V K G+ + L++ Sbjct: 295 IGSCTNGRYEDLKVAAEVLE------GEEVHDDVRLIVIPASREVYHRTLKDGVLEVLHE 348 Query: 208 LGFNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 G I C C+G + G L E V + NRNF GR+ YLA Sbjct: 349 AGALICPPNCGPCLGGHMGVLAEG-----------ERCVATSNRNFPGRMGHRESEVYLA 397 Query: 385 SPPLVVAYALAGTV 426 SP A A+ G + Sbjct: 398 SPATAAASAIEGEI 411
>LEU2_THEFY (Q47SA3) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 465 Score = 40.8 bits (94), Expect = 0.004 Identities = 38/133 (28%), Positives = 56/133 (42%), Gaps = 1/133 (0%) Frame = +1 Query: 34 SCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQLG 213 SCTN ++ A ++ G +V ++ + PGS VK+ GL + G Sbjct: 346 SCTNGRIEDLRAAAEVLK------GRKVADGVRMLVVPGSQRVKQQAAAEGLDEIFKAAG 399 Query: 214 FNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLASP 390 GC+ C+G N L +A T NRNFEGR R +L SP Sbjct: 400 AEWREAGCSMCLGMNPDTLKPGERSAST-----------SNRNFEGRQGKGGR-THLVSP 447 Query: 391 PLVVAYALAGTVN 429 + A A+ GT++ Sbjct: 448 LVAAATAVRGTLS 460
>LEU21_METAC (Q8TLF1) 3-isopropylmalate dehydratase large subunit 1 (EC| 4.2.1.33) (Isopropylmalate isomerase 1) (Alpha-IPM isomerase 1) (IPMI 1) Length = 424 Score = 40.4 bits (93), Expect = 0.005 Identities = 39/142 (27%), Positives = 59/142 (41%), Gaps = 1/142 (0%) Frame = +1 Query: 4 GTRVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKS 183 GT V I +CTN ++ + AA++ K ++T + P S ++ Sbjct: 297 GTHVDQVFIGTCTNGRLEDLEVAAAVLKGKQVA--------VRTIVIPASRTTLLAAIEN 348 Query: 184 GLQKYLNQLGFNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHA 360 G + L + G + GC C+G + G L E V + NRNF+GR+ Sbjct: 349 GTMETLLKAGVTLATPGCGPCLGAHQGVLGEG-----------EVCVSTANRNFKGRM-G 396 Query: 361 LTRANYLASPPLVVAYALAGTV 426 YLASP A AL G + Sbjct: 397 KGGFIYLASPATAAASALTGEI 418
>LEU2_BUCUS (Q9EVI3) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) (Fragment) Length = 442 Score = 40.0 bits (92), Expect = 0.007 Identities = 28/108 (25%), Positives = 46/108 (42%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN ++ + ++ K ++ +K + PGS +VK+ ++ GL + Sbjct: 344 IGSCTNARIEDLRSASKILKNK------KIAKHVKAIVVPGSKLVKRQAEQEGLDRIFID 397 Query: 208 LGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGR 351 GF GC+ C+G + D + NRNFEGR Sbjct: 398 AGFEWRLPGCSMCLGMNKDRLHFGGRCAS----------XSNRNFEGR 435
>LEU22_DEIRA (Q9RTI6) 3-isopropylmalate dehydratase large subunit 2 (EC| 4.2.1.33) (Isopropylmalate isomerase 2) (Alpha-IPM isomerase 2) (IPMI 2) Length = 431 Score = 40.0 bits (92), Expect = 0.007 Identities = 35/139 (25%), Positives = 60/139 (43%) Frame = +1 Query: 10 RVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGL 189 RV A + SCTN ++ A ++ G +V ++ + P + + K + GL Sbjct: 292 RVTHAYVGSCTNGRITDLRDVARILK------GRKVAQDVQMIVVPATQAIWKQAAQEGL 345 Query: 190 QKYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTR 369 + G ++ C C+G + + +D+ + S NRNF GR+ + Sbjct: 346 LEIFVDAGASVSYPSCGACLGMH-------SGVLGPDDI---CISSSNRNFVGRMGDPSA 395 Query: 370 ANYLASPPLVVAYALAGTV 426 YLASP V A A+ G + Sbjct: 396 QIYLASPATVAASAVEGFI 414
>LEU2_STRAW (Q82JR8) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 477 Score = 40.0 bits (92), Expect = 0.007 Identities = 38/132 (28%), Positives = 53/132 (40%), Gaps = 1/132 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 + SCTN ++ AA+V G +V ++ + PGS V GL + Sbjct: 344 VGSCTNGRIEDLRAAAAIVE------GRKVADGVRMLIVPGSARVGLQAVSEGLDVVFKE 397 Query: 208 LGFNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 G GC+ C+G N L +A T NRNFEGR R +L Sbjct: 398 AGAEWRHAGCSMCLGMNPDQLAPGERSAST-----------SNRNFEGRQGKGGR-THLV 445 Query: 385 SPPLVVAYALAG 420 SP + A A+ G Sbjct: 446 SPQVAAATAVLG 457
>LEU21_METJA (Q58409) 3-isopropylmalate dehydratase large subunit 1 (EC| 4.2.1.33) (Isopropylmalate isomerase 1) (Alpha-IPM isomerase 1) (IPMI 1) Length = 420 Score = 40.0 bits (92), Expect = 0.007 Identities = 40/142 (28%), Positives = 56/142 (39%), Gaps = 1/142 (0%) Frame = +1 Query: 4 GTRVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKS 183 GT + I SCTN ++ A + G EV +K + P S V K Sbjct: 291 GTEINQVFIGSCTNGRLSDLREAAKYLK------GREVHKDVKLIVIPASKKVFLQALKE 344 Query: 184 GLQKYLNQLGFNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHA 360 G+ + G I GC C+G + G L E T N RNF+GR+ Sbjct: 345 GIIDIFVKAGAMICTPGCGPCLGAHQGVLAEGEICLSTTN-----------RNFKGRMGH 393 Query: 361 LTRANYLASPPLVVAYALAGTV 426 + YLASP + A+ G + Sbjct: 394 INSYIYLASPKIAAISAVKGYI 415
>LEU22_METTH (O27668) 3-isopropylmalate dehydratase large subunit 2 (EC| 4.2.1.33) (Isopropylmalate isomerase 2) (Alpha-IPM isomerase 2) (IPMI 2) Length = 428 Score = 39.7 bits (91), Expect = 0.009 Identities = 31/142 (21%), Positives = 63/142 (44%) Frame = +1 Query: 4 GTRVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKS 183 GT + A + SCTN ++ + A ++ + V ++ ++P S + + Sbjct: 293 GTHIDEAFLGSCTNGRYEDLKIAAEVIGDR------RVHEDVRFIVSPASREIYLKALED 346 Query: 184 GLQKYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHAL 363 G+ + + G + GC C+G + + +V ++ + NRNF GR+ Sbjct: 347 GIIETFIRAGAIVCNPGCGPCLG-------AHMGVLAPGEV---SIATTNRNFRGRMGDP 396 Query: 364 TRANYLASPPLVVAYALAGTVN 429 + YLA+P +V A+ G ++ Sbjct: 397 ASSVYLANPAVVAESAIEGVIS 418
>LEU2_MYCLE (O33123) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 476 Score = 39.3 bits (90), Expect = 0.012 Identities = 37/132 (28%), Positives = 58/132 (43%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 + SCTN ++ L A ++ G +V ++ + PGS V+ + GL + Sbjct: 354 VGSCTNGRIEDLRLVADVLR------GHKVADGVRMLIVPGSMRVRAQAEAEGLGEIFIT 407 Query: 208 LGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLAS 387 G GC+ C+G + D + + AA + NRNFEGR R +L S Sbjct: 408 AGAQWRQPGCSMCLGMNPD-------QLAPGERCAA---TSNRNFEGRQGKGGR-THLVS 456 Query: 388 PPLVVAYALAGT 423 P + A A+ GT Sbjct: 457 PAVAAATAVRGT 468
>LEU2_CORJK (Q4JUX2) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 473 Score = 39.3 bits (90), Expect = 0.012 Identities = 37/130 (28%), Positives = 53/130 (40%), Gaps = 1/130 (0%) Frame = +1 Query: 34 SCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQLG 213 SCTN+ ++ A ++ G V + + P S VK ++ GL + G Sbjct: 354 SCTNSRIEDLRAAADVLK------GRTVADGTRMIVVPSSTRVKMQAEEEGLDQIFIDAG 407 Query: 214 FNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLASP 390 GC+ C+G N L +A T NRNFEGR R +L SP Sbjct: 408 AEWRTAGCSMCLGMNPDQLAPGERSAST-----------SNRNFEGRQGKGGR-THLVSP 455 Query: 391 PLVVAYALAG 420 P+ A A+ G Sbjct: 456 PVAAATAVTG 465
>LEU21_THEMA (Q9WYC7) 3-isopropylmalate dehydratase large subunit 1 (EC| 4.2.1.33) (Isopropylmalate isomerase 1) (Alpha-IPM isomerase 1) (IPMI 1) Length = 418 Score = 38.9 bits (89), Expect = 0.015 Identities = 36/136 (26%), Positives = 58/136 (42%), Gaps = 3/136 (2%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLD--KSGLQKYL 201 I +CTN ++ + ++ K P ++ + P S K Y+D + G+ K Sbjct: 295 IGTCTNGRLQDLEIALKILEKHG------KHPDVRLIVGPASR--KVYMDALEKGIIKKF 346 Query: 202 NQLGFNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANY 378 +LG ++ GC C+G + G L + T N RNF+GR+ Y Sbjct: 347 VELGAAVIPPGCGPCVGIHMGVLGDGERVLSTQN-----------RNFKGRMGNPNAEIY 395 Query: 379 LASPPLVVAYALAGTV 426 LASP A A+ G + Sbjct: 396 LASPATAAATAVTGYI 411
>LEU2_MYCSM (Q938C9) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 422 Score = 38.5 bits (88), Expect = 0.020 Identities = 34/135 (25%), Positives = 53/135 (39%) Frame = +1 Query: 22 AAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYL 201 A I SC N ++ + A ++ G V P ++ + P S V + + G + + Sbjct: 289 AFIGSCANGQLDDLRIAAEILR------GRRVAPGVRLIVTPASQQVYRDAMRLGYLQDI 342 Query: 202 NQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYL 381 G I C C G + +T S RNF GR+ + Y+ Sbjct: 343 ADAGAVITNSTCGACFGYHMGVVGPGEVCLT----------SSTRNFTGRMGSTEAEIYM 392 Query: 382 ASPPLVVAYALAGTV 426 ASP V A A+AG + Sbjct: 393 ASPATVAASAVAGHI 407
>LEU21_ARCFU (O28316) 3-isopropylmalate dehydratase large subunit 1 (EC| 4.2.1.33) (Isopropylmalate isomerase 1) (Alpha-IPM isomerase 1) (IPMI 1) Length = 418 Score = 38.1 bits (87), Expect = 0.026 Identities = 38/141 (26%), Positives = 59/141 (41%) Frame = +1 Query: 4 GTRVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKS 183 GTRV I SCTN ++ + A ++ G +V ++ + P S + K Sbjct: 287 GTRVDQVFIGSCTNGRYEDLKIAAEILK------GEKVASNVRLIVIPASHREYRRALKE 340 Query: 184 GLQKYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHAL 363 GL + G + C C+G S L I +V +V + NRNF GR + Sbjct: 341 GLIEIFVDAGALVEAPCCGPCMGGSFGL-------IASGEV---SVSTSNRNFIGRQGSP 390 Query: 364 TRANYLASPPLVVAYALAGTV 426 YL +P + A A+ G + Sbjct: 391 EGKIYLVNPAVAAATAIYGEI 411
>LEU21_PYRAB (Q9UZ07) 3-isopropylmalate dehydratase large subunit 1 (EC| 4.2.1.33) (Isopropylmalate isomerase 1) (Alpha-IPM isomerase 1) (IPMI 1) Length = 423 Score = 38.1 bits (87), Expect = 0.026 Identities = 35/133 (26%), Positives = 55/133 (41%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 I SCTN ++ + A ++ G +V W++ + P S V K GL + + Sbjct: 299 IGSCTNGRIEDLRMAAEILE------GQKVAKWVRLIVIPCSPTVYWKALKEGLIEIFLE 352 Query: 208 LGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLAS 387 G I C C+G + S A++ NRNF GR+ YLA+ Sbjct: 353 AGAVIGPPTCGPCLGGHMGVLASGERAVSTT----------NRNFVGRMGHPKSEVYLAN 402 Query: 388 PPLVVAYALAGTV 426 P + A A+ G + Sbjct: 403 PYVAAASAVLGRI 415
>LEU21_DEIRA (Q9RTY9) 3-isopropylmalate dehydratase large subunit 1 (EC| 4.2.1.33) (Isopropylmalate isomerase 1) (Alpha-IPM isomerase 1) (IPMI 1) Length = 434 Score = 37.4 bits (85), Expect = 0.045 Identities = 39/153 (25%), Positives = 60/153 (39%) Frame = +1 Query: 4 GTRVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKS 183 G +V I +CTN ++ A ++ G V P + + P S V + + Sbjct: 297 GLKVDQVFIGTCTNGRIEDLHAAAEVLR------GRRVDPTTRLLVIPASSQVMEEALQD 350 Query: 184 GLQKYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHAL 363 G L + G + GC C+G + +V V + NRNF GR+ Sbjct: 351 GTLLTLQRAGAVLGTPGCGPCMGRH-------QGVLAPGEV---CVSTSNRNFIGRMGDK 400 Query: 364 TRANYLASPPLVVAYALAGTVNIDFEKEPVGIS 462 YLASP + A A+ G V + + V S Sbjct: 401 DAHIYLASPAVAAATAVMGRVALPEDVAQVAAS 433
>LEU22_METJA (P81291) 3-isopropylmalate dehydratase large subunit 2 (EC| 4.2.1.33) (Isopropylmalate isomerase 2) (Alpha-IPM isomerase 2) (IPMI 2) Length = 424 Score = 37.0 bits (84), Expect = 0.058 Identities = 38/136 (27%), Positives = 59/136 (43%), Gaps = 5/136 (3%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKK---ACDLGLEVKPWIKTSL--APGSGVVKKYLDKSGLQ 192 I SCTN ++ + ++ K A D+ + V P + A G+++K+L Sbjct: 301 IGSCTNGRLEDLRMAIKIIEKHGGIADDVRVVVTPASREEYLKALKEGIIEKFL------ 354 Query: 193 KYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRA 372 KY G + C+ C+G S+ + +V V + NRNF GR +L Sbjct: 355 KY----GCVVTNPSCSACMG-------SLYGVLGPGEV---CVSTSNRNFRGRQGSLEAE 400 Query: 373 NYLASPPLVVAYALAG 420 YLASP A A+ G Sbjct: 401 IYLASPITAAACAVKG 416
>LEU2_STRCO (O86534) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 476 Score = 36.6 bits (83), Expect = 0.076 Identities = 36/132 (27%), Positives = 52/132 (39%), Gaps = 1/132 (0%) Frame = +1 Query: 28 ITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQ 207 + SCTN ++ A +V + +V ++ + PGS V GL + Sbjct: 344 VGSCTNGRIEDLRAAAEIVRDR------KVADGVRMLVVPGSARVGLQAVSEGLDVVFKE 397 Query: 208 LGFNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHALTRANYLA 384 G GC+ C+G N L +A T NRNFEGR R +L Sbjct: 398 AGAEWRHAGCSMCLGMNPDQLAPGERSAST-----------SNRNFEGRQGKGGR-THLV 445 Query: 385 SPPLVVAYALAG 420 SP + A A+ G Sbjct: 446 SPQVAAATAVLG 457
>LEU2_BUCUD (Q9EVE0) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) (Fragment) Length = 444 Score = 36.6 bits (83), Expect = 0.076 Identities = 32/114 (28%), Positives = 48/114 (42%), Gaps = 7/114 (6%) Frame = +1 Query: 31 TSCTNTSNPNVMLGAALVAK-----KACDL--GLEVKPWIKTSLAPGSGVVKKYLDKSGL 189 T TN S V +G+ A+ A + ++ +K + PGSG+VKK ++ GL Sbjct: 333 TYLTNISIDKVFIGSXTNARIEDLRSAAKILQNRKIAKHVKAIVVPGSGLVKKKAEQEGL 392 Query: 190 QKYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGR 351 K GF GC+ +G + D + + NRNFEGR Sbjct: 393 DKIFIDSGFEWRLPGCSMXLGMNKDRLNFGERXXSHS----------NRNFEGR 436
>LEU22_METAC (Q8TQZ3) 3-isopropylmalate dehydratase large subunit 2 (EC| 4.2.1.33) (Isopropylmalate isomerase 2) (Alpha-IPM isomerase 2) (IPMI 2) Length = 420 Score = 36.2 bits (82), Expect = 0.099 Identities = 36/141 (25%), Positives = 59/141 (41%) Frame = +1 Query: 4 GTRVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKS 183 GT++ + SCTN ++ + A ++ + G ++ + P S L K+ Sbjct: 290 GTKLDQVFMGSCTNGRFEDIKIMADIMGDEPVAKG------VRLLVVPASKTEYMKLLKA 343 Query: 184 GLQKYLNQLGFNIVGYGCTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHAL 363 G + L G + C C+G S L + +V A + NRNF+GR + Sbjct: 344 GYVEKLMNAGAIVEAPCCGPCMGGSFGL-------LGPGEVGLA---TSNRNFKGREGSA 393 Query: 364 TRANYLASPPLVVAYALAGTV 426 YL+SP A AL G + Sbjct: 394 ESFVYLSSPATAGASALTGEI 414
>LUXD2_PHOLU (P23148) Acyl transferase (EC 2.3.1.-) (ACT)| (Myristoyl-ACP-specific thioesterase) (C14ACP-TE) Length = 307 Score = 35.0 bits (79), Expect = 0.22 Identities = 32/118 (27%), Positives = 52/118 (44%), Gaps = 2/118 (1%) Frame = +1 Query: 112 EVKPWIKTSLAPGSGVVKKYLDKSGLQKYLNQLGFNIVGYGCTTCIG-NSGDLDESVAAA 288 E P K +L SG ++ +GL +YL+Q GF+++ Y +G +SG +DE + Sbjct: 31 ENSPKRKNTLIIASGFARRMDHFAGLAEYLSQNGFHVIRYDSLHHVGLSSGTIDE-FTMS 89 Query: 289 ITDNDVVAAAVLSGNRNFEGRVHALTRANYLASP-PLVVAYALAGTVNIDFEKEPVGI 459 I ++A R + LAS +AYA +N+ F VG+ Sbjct: 90 IGKQSLLAVVDWLNTRK-------INNLGMLASSLSARIAYASLSEINVSFLITAVGV 140
>LUXD_SHEHA (Q9AJA7) Acyl transferase (EC 2.3.1.-) (ACT)| (Myristoyl-ACP-specific thioesterase) (C14ACP-TE) Length = 308 Score = 33.9 bits (76), Expect = 0.49 Identities = 27/105 (25%), Positives = 50/105 (47%), Gaps = 2/105 (1%) Frame = +1 Query: 151 SGVVKKYLDKSGLQKYLNQLGFNIVGYGCTTCIG-NSGDLDESVAAAITDNDVVAAAVLS 327 SG ++ +GL +YL+ GF+++ Y +G +SGD++E + D+ ++ L Sbjct: 44 SGFARRMDHFAGLAEYLSSNGFHVIRYDSLHHVGLSSGDINEFTMSIGKDSLLIVIEWLK 103 Query: 328 GNR-NFEGRVHALTRANYLASPPLVVAYALAGTVNIDFEKEPVGI 459 G N G + A A +AY ++ V++ F VG+ Sbjct: 104 GRGVNKLGLIAASLSAR--------IAYEISNDVDLSFLVTAVGV 140
>LEU2_PYRAE (Q8ZW41) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 415 Score = 33.9 bits (76), Expect = 0.49 Identities = 39/142 (27%), Positives = 55/142 (38%), Gaps = 1/142 (0%) Frame = +1 Query: 4 GTRVVIAAITSCTNTSNPNVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVKKYLDKS 183 G V I SCTN ++ + A ++ G VK + P S V + K Sbjct: 284 GVEVDQVFIGSCTNGRLSDIAVAAKILK------GRRVKS--RCIAIPASYEVFRRAMKL 335 Query: 184 GLQKYLNQLGFNIVGYG-CTTCIGNSGDLDESVAAAITDNDVVAAAVLSGNRNFEGRVHA 360 G L + G +V YG C C+G + +T + NRNF GRV Sbjct: 336 GYIDVLTEAGC-VVTYGTCGPCLGGHFGVAGPGEVVVT----------TSNRNFRGRVGH 384 Query: 361 LTRANYLASPPLVVAYALAGTV 426 YLA+P + A A G + Sbjct: 385 PDAKIYLANPAVAAATAAEGKI 406 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.316 0.134 0.403 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 104,371,569 Number of Sequences: 219361 Number of extensions: 2265202 Number of successful extensions: 6594 Number of sequences better than 10.0: 270 Number of HSP's better than 10.0 without gapping: 6213 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6515 length of database: 80,573,946 effective HSP length: 109 effective length of database: 56,663,597 effective search space used: 7026286028 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits)
