>PEPL_HUMAN (O60437) Periplakin (195 kDa cornified envelope precursor protein)|
            (190 kDa paraneoplastic pemphigus antigen)
          Length = 1756

 Score = 37.0 bits (84), Expect = 0.049
 Identities = 33/134 (24%), Positives = 61/134 (45%), Gaps = 7/134 (5%)
 Frame = +3

Query: 261  LKGLVDRATNTSDNCREVDIDMDVLVFL----VKEEFGIARPVLNMMREAAEVAQADRAN 428
            LK  +    +T    +  ++  ++L F      KEE    R  L+  ++     + +RA+
Sbjct: 1272 LKKEIQALKDTKPQVQTKEVVQEILQFQEDPQTKEEVASLRAKLSEEQKKQVDLERERAS 1331

Query: 429  LWHQICATEDENIRLREE-MDMDQTKFTNEKAVLAQRLTESEATTGHLR--SELKAEKDR 599
               QI   E+E  R++E  +  +  ++  E  + A+    +E+    LR   +L+AE  R
Sbjct: 1332 QEEQIARKEEELSRVKERVVQQEVVRYEEEPGLRAEASAFAESIDVELRQIDKLRAELRR 1391

Query: 600  HIREKKELSRQMRE 641
              R + EL RQ+ E
Sbjct: 1392 LQRRRTELERQLEE 1405

>GOGB1_HUMAN (Q14789) Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa|
            Golgi complex-associated protein) (GCP372)
          Length = 3259

 Score = 34.7 bits (78), Expect = 0.25
 Identities = 31/102 (30%), Positives = 51/102 (50%)
 Frame = +3

Query: 336  VFLVKEEFGIARPVLNMMREAAEVAQADRANLWHQICATEDENIRLREEMDMDQTKFTNE 515
            V LVKE   I+ P           ++  +  L  +I A E E  +L++++   Q   T+ 
Sbjct: 1138 VALVKETVVISPPCTGS-------SEHWKPELEEKILALEKEKEQLQKKL---QEALTSR 1187

Query: 516  KAVLAQRLTESEATTGHLRSELKAEKDRHIREKKELSRQMRE 641
            KA+L ++  E E    HLR ELK +KD + R +++   Q +E
Sbjct: 1188 KAIL-KKAQEKER---HLREELKQQKDDYNRLQEQFDEQSKE 1225

>TRHY_RABIT (P37709) Trichohyalin|
          Length = 1407

 Score = 34.3 bits (77), Expect = 0.32
 Identities = 19/60 (31%), Positives = 33/60 (55%)
 Frame = +3

Query: 453  EDENIRLREEMDMDQTKFTNEKAVLAQRLTESEATTGHLRSELKAEKDRHIREKKELSRQ 632
            E+E +  +EE ++ Q +        A++L E E        EL+ E+DR +RE+++L RQ
Sbjct: 848  EEEQLLRQEEQELRQER--------ARKLREEEQLLRQEEQELRQERDRKLREEEQLLRQ 899



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 18/60 (30%), Positives = 32/60 (53%)
 Frame = +3

Query: 453  EDENIRLREEMDMDQTKFTNEKAVLAQRLTESEATTGHLRSELKAEKDRHIREKKELSRQ 632
            E+E +  +EE ++ Q +        A++L E E        EL+ E+DR  RE+++L R+
Sbjct: 1196 EEEQLLRQEEQELRQER--------ARKLREEEQLLRQEEQELRQERDRKFREEEQLLRR 1247



 Score = 30.8 bits (68), Expect = 3.5
 Identities = 17/63 (26%), Positives = 33/63 (52%)
 Frame = +3

Query: 453  EDENIRLREEMDMDQTKFTNEKAVLAQRLTESEATTGHLRSELKAEKDRHIREKKELSRQ 632
            E+E +  +EE ++ Q +         ++L E E        EL+ E+DR +RE+++L ++
Sbjct: 870  EEEQLLRQEEQELRQER--------DRKLREEEQLLRQEEQELRQERDRKLREEEQLLQE 921

Query: 633  MRE 641
              E
Sbjct: 922  SEE 924

>REST_CHICK (O42184) Restin (Cytoplasmic linker protein 170) (CLIP-170)|
          Length = 1433

 Score = 33.5 bits (75), Expect = 0.55
 Identities = 22/112 (19%), Positives = 52/112 (46%), Gaps = 6/112 (5%)
 Frame = +3

Query: 276  DRATNTSDNCREVDIDMDVLVFLVKEEFGIARPVLNMMREAAEVAQADRANLWHQICATE 455
            ++  N  D  ++ ++  +  +   KE   +    +  +++  E  +   A    Q+ A +
Sbjct: 1108 EKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQ 1167

Query: 456  DENIRLREEMDMDQTKFTN------EKAVLAQRLTESEATTGHLRSELKAEK 593
            +EN++L EE+   + + T+      E++VL  +L E +     L+ E+  E+
Sbjct: 1168 EENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESTLKKEIDEER 1219

>REST_HUMAN (P30622) Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170)|
            (Reed-Sternberg intermediate filament-associated protein)
            (Cytoplasmic linker protein 1)
          Length = 1427

 Score = 33.1 bits (74), Expect = 0.71
 Identities = 20/91 (21%), Positives = 41/91 (45%)
 Frame = +3

Query: 348  KEEFGIARPVLNMMREAAEVAQADRANLWHQICATEDENIRLREEMDMDQTKFTNEKAVL 527
            KE   +    +   R+  E  +   A    Q+ A ++EN++L EE+   + + T+     
Sbjct: 1130 KELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSH---- 1185

Query: 528  AQRLTESEATTGHLRSELKAEKDRHIREKKE 620
             Q+L E  +   +   E+K  + + I++  E
Sbjct: 1186 -QKLEEERSVLNNQLLEMKKRESKFIKDADE 1215

>ACE_HAEIE (Q10715) Angiotensin-converting enzyme precursor (EC 3.4.15.1)|
           (Dipeptidyl carboxypeptidase I) (Kininase II)
          Length = 611

 Score = 32.7 bits (73), Expect = 0.93
 Identities = 21/80 (26%), Positives = 33/80 (41%)
 Frame = +3

Query: 348 KEEFGIARPVLNMMREAAEVAQADRANLWHQICATEDENIRLREEMDMDQTKFTNEKAVL 527
           KEE      + N+ +E A+    +    W       DEN RLR E+  +  KF  E A  
Sbjct: 20  KEEIVATEYLQNINKELAKHTNVETEVSWAYASNITDENERLRNEISAENAKFLKEVAKD 79

Query: 528 AQRLTESEATTGHLRSELKA 587
            Q+       +  +R + K+
Sbjct: 80  IQKFNWRTYGSADVRRQFKS 99

>CP51A_PIG (O46420) Cytochrome P450 51A1 (EC 1.14.13.70) (CYPLI) (P450LI)|
           (Sterol 14-alpha demethylase) (Lanosterol 14-alpha
           demethylase) (LDM) (P450-14DM)
          Length = 503

 Score = 32.7 bits (73), Expect = 0.93
 Identities = 37/163 (22%), Positives = 66/163 (40%), Gaps = 11/163 (6%)
 Frame = +3

Query: 81  QVLLDGQFEPS-PIQEGEFTSVLA----LGEVLSLSTSARVQDFVRMLYAIMFKIYAEDH 245
           Q LLD  ++   P+ + E   +L      G+  S +TSA +  F+     +  K Y E  
Sbjct: 283 QTLLDSTYKDGRPLTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQEKCYLEQK 342

Query: 246 YRCRFLKGLVDRATNTSDNCREVDIDMDVLVFLVKEEFGIARPVLNMMREA--AEVAQAD 419
             C       D    T D  +    D+++L   +KE   +  P++ MMR A   +     
Sbjct: 343 TVCG-----EDLPPLTYDQLK----DLNLLDRCIKETLRLRPPIMTMMRMAKTPQTVAGY 393

Query: 420 RANLWHQICATEDENIRLR----EEMDMDQTKFTNEKAVLAQR 536
                HQ+C +   N RL+    E +D +  ++  +     ++
Sbjct: 394 TIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPASGEK 436

>NUMA1_HUMAN (Q14980) Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H|
           antigen)
          Length = 2115

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 23/90 (25%), Positives = 40/90 (44%), Gaps = 12/90 (13%)
 Frame = +3

Query: 399 AEVAQADRANLWHQICATEDENIR------------LREEMDMDQTKFTNEKAVLAQRLT 542
           A+VA+ +      Q  ATE E +             L+E + + +     EK   A  L 
Sbjct: 671 AQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALE 730

Query: 543 ESEATTGHLRSELKAEKDRHIREKKELSRQ 632
           E +     L++E ++  ++H RE+KEL  +
Sbjct: 731 EQQRCISELKAETRSLVEQHKRERKELEEE 760



 Score = 29.6 bits (65), Expect = 7.9
 Identities = 22/88 (25%), Positives = 37/88 (42%), Gaps = 3/88 (3%)
 Frame = +3

Query: 387 MREAAEVAQADRANLWHQICATEDE---NIRLREEMDMDQTKFTNEKAVLAQRLTESEAT 557
           ++E AE  +A R +   Q+    +E   ++R R+           EKA   + L +    
Sbjct: 567 LKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQV 626

Query: 558 TGHLRSELKAEKDRHIREKKELSRQMRE 641
               R   +    +  REK ELSR++ E
Sbjct: 627 ANEARDSAQTSVTQAQREKAELSRKVEE 654

>ITSN2_MOUSE (Q9Z0R6) Intersectin-2 (SH3 domain-containing protein 1B) (EH and|
           SH3 domains protein 2) (EH domain and SH3 domain
           regulator of endocytosis 2)
          Length = 1658

 Score = 32.0 bits (71), Expect = 1.6
 Identities = 20/54 (37%), Positives = 27/54 (50%), Gaps = 2/54 (3%)
 Frame = +3

Query: 393 EAAEVAQADRANLWHQICATEDE--NIRLREEMDMDQTKFTNEKAVLAQRLTES 548
           EAA  A+  + NLW +    E+E    RL+EE   D+T+    KA   Q  T S
Sbjct: 664 EAARKAKQGKENLWRESIRKEEEEKQKRLQEEKSQDKTQEEERKAEAKQSETAS 717

>KLPA_EMENI (P28739) Kinesin-like protein klpA|
          Length = 770

 Score = 32.0 bits (71), Expect = 1.6
 Identities = 24/97 (24%), Positives = 41/97 (42%), Gaps = 15/97 (15%)
 Frame = +3

Query: 387 MREAAEVAQADRANLWHQICATEDENIRLREEMDMDQTKFTNEKAVLAQRLTESEATTGH 566
           +++A EV ++    L        ++NIRL+ E+D+ +++    +  L     + E     
Sbjct: 180 LKDALEVYKSRVGELEEAKSEQTEQNIRLKVELDVSKSRLAEAEDALKNAQRDHEIAIDE 239

Query: 567 LRSELKAE---------------KDRHIREKKELSRQ 632
           L S  +AE               K +H  E KEL RQ
Sbjct: 240 LMSRQRAECESVRYESQKSLDALKAQHESELKELRRQ 276

>GOGA3_MOUSE (P55937) Golgin subfamily A member 3 (Golgin-160) (Male-enhanced|
            antigen 2) (MEA-2)
          Length = 1487

 Score = 31.6 bits (70), Expect = 2.1
 Identities = 22/78 (28%), Positives = 38/78 (48%)
 Frame = +3

Query: 402  EVAQADRANLWHQICATEDENIRLREEMDMDQTKFTNEKAVLAQRLTESEATTGHLRSEL 581
            E  + D A   +Q+   + E   LR++M   + +F  +K V+ +       +   L +EL
Sbjct: 807  EQLRQDLAVKSNQVEHLQQETATLRKQMQKVKEQFVQQK-VMVEAYRRDATSKDQLINEL 865

Query: 582  KAEKDRHIREKKELSRQM 635
            KA K R   E KEL +++
Sbjct: 866  KATKKRLDSEMKELRQEL 883

>RB6I2_RAT (Q811U3) RAB6-interacting protein 2 (ERC protein 1) (ERC1)|
           (CAZ-associated structural protein 2) (CAST2)
          Length = 948

 Score = 31.6 bits (70), Expect = 2.1
 Identities = 48/201 (23%), Positives = 75/201 (37%)
 Frame = +3

Query: 18  RRHSHKLSSKSGAVVYDLQSKQVLLDGQFEPSPIQEGEFTSVLALGEVLSLSTSARVQDF 197
           R HS  + +K G V  +L  K   L            +F+      EVL  S +A+ Q  
Sbjct: 430 RSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRA 489

Query: 198 VRMLYAIMFKIYAEDHYRCRFLKGLVDRATNTSDNCREVDIDMDVLVFLVKEEFGIARPV 377
             +   +       D  R R    L ++ T  +   +++  DM         E    + +
Sbjct: 490 AILQTEV-------DALRLR----LEEKETMLNKKTKQIQ-DMAEEKGTQAGEIHDLKDM 537

Query: 378 LNMMREAAEVAQADRANLWHQICATEDENIRLREEMDMDQTKFTNEKAVLAQRLTESEAT 557
           L++      V Q    NL  Q+   E +   L+E +   Q   TN    L   L E+ A 
Sbjct: 538 LDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTT-LEEALAD 596

Query: 558 TGHLRSELKAEKDRHIREKKE 620
                  LK ++DR  REK+E
Sbjct: 597 KERTIERLKEQRDRDEREKQE 617

>YBE7_YEAST (P34216) Protein YBL047C|
          Length = 1381

 Score = 31.2 bits (69), Expect = 2.7
 Identities = 17/65 (26%), Positives = 34/65 (52%)
 Frame = +3

Query: 447 ATEDENIRLREEMDMDQTKFTNEKAVLAQRLTESEATTGHLRSELKAEKDRHIREKKELS 626
           +T D+N++  E+++    +   E   LAQ+L  SEA      S+L  E    ++E +  +
Sbjct: 653 STHDQNVKQTEQLEAQVLQVNKENETLAQQLAVSEANYHAAESKLN-ELTTDLQESQTKN 711

Query: 627 RQMRE 641
            +++E
Sbjct: 712 AELKE 716

>CCD43_BRARE (Q6PFL6) Coiled-coil domain-containing protein 43|
          Length = 213

 Score = 31.2 bits (69), Expect = 2.7
 Identities = 30/131 (22%), Positives = 60/131 (45%), Gaps = 4/131 (3%)
 Frame = +3

Query: 261 LKGLVDRATNTSDNCREVDIDMDVLVFLVKEEFGIA---RPVLNMMREAAEVAQADRANL 431
           LK   +  + +     + D ++  +  L++++  I    + V    ++  E   A  AN+
Sbjct: 71  LKQWTECCSRSGAKSNQADAEVQAIASLIEKQAQIVVKQKEVSEDAKKRKEAVLAQYANV 130

Query: 432 WH-QICATEDENIRLREEMDMDQTKFTNEKAVLAQRLTESEATTGHLRSELKAEKDRHIR 608
              +  A E+E + +    D    K TN + VL +R  + +       ++ K E+D+  R
Sbjct: 131 TDDEDEAEEEEQVPVGIPSDKSLFKNTNVEDVLNRRKLQRDQAKED--AQKKKEQDKMQR 188

Query: 609 EKKELSRQMRE 641
           EK +LS+Q R+
Sbjct: 189 EKDKLSKQERK 199

>CP51A_RAT (Q64654) Cytochrome P450 51A1 (EC 1.14.13.70) (CYPLI) (P450LI)|
           (Sterol 14-alpha demethylase) (Lanosterol 14-alpha
           demethylase) (LDM) (P450-14DM)
          Length = 503

 Score = 31.2 bits (69), Expect = 2.7
 Identities = 36/163 (22%), Positives = 66/163 (40%), Gaps = 11/163 (6%)
 Frame = +3

Query: 81  QVLLDGQFEPS-PIQEGEFTSVLA----LGEVLSLSTSARVQDFVRMLYAIMFKIYAEDH 245
           Q LLD  ++   P+ + E   +L      G+  S +TSA +  F+     +  K Y E  
Sbjct: 283 QTLLDSTYKDGRPLTDDEIAGMLIGLLLAGQHTSSTTSAWMGFFLARDKPLQDKCYLEQK 342

Query: 246 YRCRFLKGLVDRATNTSDNCREVDIDMDVLVFLVKEEFGIARPVLNMMREA--AEVAQAD 419
             C       D    T +  +    D+++L   +KE   +  P++ MMR A   +     
Sbjct: 343 TVCG-----EDLPPLTYEQLK----DLNLLDRCIKETLRLRPPIMTMMRMAKTPQTVAGY 393

Query: 420 RANLWHQICATEDENIRLR----EEMDMDQTKFTNEKAVLAQR 536
                HQ+C +   N RL+    E +D +  ++  +     ++
Sbjct: 394 TIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPASGEK 436

>RB6I2_HUMAN (Q8IUD2) RAB6-interacting protein 2 (ERC protein 1)|
          Length = 1116

 Score = 30.8 bits (68), Expect = 3.5
 Identities = 24/84 (28%), Positives = 36/84 (42%)
 Frame = +3

Query: 369 RPVLNMMREAAEVAQADRANLWHQICATEDENIRLREEMDMDQTKFTNEKAVLAQRLTES 548
           + +L++      V Q    NL  Q+   E +   L+E +   Q   TN    L   L E+
Sbjct: 563 KDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTT-LEEA 621

Query: 549 EATTGHLRSELKAEKDRHIREKKE 620
            A        LK ++DR  REK+E
Sbjct: 622 LAEKERTIERLKEQRDRDEREKQE 645

>DBP9_CANGA (Q6FUA6) ATP-dependent RNA helicase DBP9 (EC 3.6.1.-)|
          Length = 595

 Score = 30.8 bits (68), Expect = 3.5
 Identities = 30/110 (27%), Positives = 52/110 (47%), Gaps = 8/110 (7%)
 Frame = +3

Query: 315 DIDMDVLVFLVKEEFGIARPVLNMMREA---AEVAQADRANLWHQICATED-ENIRLREE 482
           +ID    + LV E+FGI   +LN    A     +      N++H + AT+D +NI+  ++
Sbjct: 279 NIDRGYRLKLVLEQFGIKSCILNNELPANSRQHIVDQFNKNVYHLLIATDDADNIKEFDD 338

Query: 483 MDMD----QTKFTNEKAVLAQRLTESEATTGHLRSELKAEKDRHIREKKE 620
              D    + K      V+A+  T S  TTG     +K++   + ++ KE
Sbjct: 339 EQKDDIQVEEKNDETNTVVAEESTNS--TTG-----IKSKTKNNYKQDKE 381

>RB6I2_MOUSE (Q99MI1) RAB6-interacting protein 2 (ERC protein 1) (ERC1)|
           (CAZ-associated structural protein 2) (CAST2)
          Length = 1120

 Score = 30.8 bits (68), Expect = 3.5
 Identities = 24/84 (28%), Positives = 36/84 (42%)
 Frame = +3

Query: 369 RPVLNMMREAAEVAQADRANLWHQICATEDENIRLREEMDMDQTKFTNEKAVLAQRLTES 548
           + +L++      V Q    NL  Q+   E +   L+E +   Q   TN    L   L E+
Sbjct: 563 KDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTT-LEEA 621

Query: 549 EATTGHLRSELKAEKDRHIREKKE 620
            A        LK ++DR  REK+E
Sbjct: 622 LADKERTIERLKEQRDRDEREKQE 645

>CAC1B_HUMAN (Q00975) Voltage-dependent N-type calcium channel alpha-1B subunit|
           (Voltage-gated calcium channel alpha subunit Cav2.2)
           (Calcium channel, L type, alpha-1 polypeptide isoform 5)
           (Brain calcium channel III) (BIII)
          Length = 2339

 Score = 30.4 bits (67), Expect = 4.6
 Identities = 26/92 (28%), Positives = 39/92 (42%), Gaps = 9/92 (9%)
 Frame = +3

Query: 351 EEFGIARPVLNMMREAAEVAQADRANLWHQICATEDENIRLRE--EMDMDQTKFTNEKAV 524
           EE    +  L   +E AEV+    AN+   I A +  + + R   E    Q +  N +A 
Sbjct: 726 EEAANQKLALQKAKEVAEVSPMSAANI--SIAARQQNSAKARSVWEQRASQLRLQNLRAS 783

Query: 525 LAQRLTESE-------ATTGHLRSELKAEKDR 599
                +E +       ATT HLR ++K   DR
Sbjct: 784 CEALYSEMDPEERLRFATTRHLRPDMKTHLDR 815

>SIR4_YEAST (P11978) Regulatory protein SIR4 (Silent information regulator 4)|
          Length = 1358

 Score = 30.0 bits (66), Expect = 6.0
 Identities = 14/28 (50%), Positives = 19/28 (67%)
 Frame = -2

Query: 434 PKISTIGLSNFSSFPHHV*HRSSNSKLL 351
           PK S +  +N++SFPH    + SNSKLL
Sbjct: 81  PKSSPLKKNNYNSFPHSNLEKISNSKLL 108

>DBP9_YEAST (Q06218) ATP-dependent RNA helicase DBP9 (EC 3.6.1.-) (DEAD box|
           protein 9)
          Length = 594

 Score = 30.0 bits (66), Expect = 6.0
 Identities = 22/105 (20%), Positives = 46/105 (43%), Gaps = 3/105 (2%)
 Frame = +3

Query: 315 DIDMDVLVFLVKEEFGIARPVLNM---MREAAEVAQADRANLWHQICATEDENIRLREEM 485
           +ID    + LV E+FGI   +LN    +     +      N++  + AT+D      E+ 
Sbjct: 282 NIDRGYRLKLVMEQFGIKSCILNSELPVNSRQHIVDQFNKNVYQLLIATDDTEYIKEEDD 341

Query: 486 DMDQTKFTNEKAVLAQRLTESEATTGHLRSELKAEKDRHIREKKE 620
           ++++   T  +        E ++  G   ++ K  K + ++ KK+
Sbjct: 342 EIEEGHNTENQ--------EEKSLEGEPENDKKPSKKKKVQVKKD 378

>DBP9_KLULA (Q6CUI6) ATP-dependent RNA helicase DBP9 (EC 3.6.1.-)|
          Length = 594

 Score = 30.0 bits (66), Expect = 6.0
 Identities = 24/100 (24%), Positives = 44/100 (44%), Gaps = 5/100 (5%)
 Frame = +3

Query: 315 DIDMDVLVFLVKEEFGIARPVLNMMREA---AEVAQADRANLWHQICATEDENIRLREEM 485
           +ID    + LV E+FGI   +LN    A     + +    N++  + AT+D      E+ 
Sbjct: 278 NIDRGYRLKLVLEQFGIKSCILNSELPANSRQHIVEEFNKNVYQLLIATDDTEYIKEEDE 337

Query: 486 DMDQTKFTN--EKAVLAQRLTESEATTGHLRSELKAEKDR 599
           D++  K  +   + V    +T  +      + +L  EKD+
Sbjct: 338 DLESEKTEDGLVEVVDDSTVTTKDNAKKQKKPKLNVEKDK 377

>CLPB_TREDE (Q73K92) Chaperone clpB|
          Length = 859

 Score = 30.0 bits (66), Expect = 6.0
 Identities = 37/185 (20%), Positives = 72/185 (38%), Gaps = 7/185 (3%)
 Frame = +3

Query: 78  KQVLLDGQFE----PSPIQEGEFTSVLALGEVLSLSTSARVQDFVRMLYAIMFKIYAEDH 245
           K   L+ +F+    P P  E     +  L E   +    R++D   +  A++   Y  + 
Sbjct: 325 KDAALERRFQQVYCPEPTVEDTIAILRGLQEKYEVHHGVRIRDEALIAAAVLSNRYITNR 384

Query: 246 YRCRFLKGLVDRATNTSD---NCREVDIDMDVLVFLVKEEFGIARPVLNMMREAAEVAQA 416
           +       LVD A +        + V++D             + R +L +  E   + + 
Sbjct: 385 FLPDKAIDLVDEAASRLKMEIESQPVELDQ------------VERKILQLNIEKVSIGKE 432

Query: 417 DRANLWHQICATEDENIRLREEMDMDQTKFTNEKAVLAQRLTESEATTGHLRSELKAEKD 596
           +      ++   E+E   L  + +  Q ++ NEKA    R+ ES      L  +L+ E+ 
Sbjct: 433 NDTASKERLLKLEEELAELSSKRNAMQAQWQNEKA----RINESRKYKEEL-EQLRIEET 487

Query: 597 RHIRE 611
           ++ RE
Sbjct: 488 KYSRE 492

>MYH13_HUMAN (Q9UKX3) Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular)|
            (MyHC-eo)
          Length = 1938

 Score = 30.0 bits (66), Expect = 6.0
 Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 7/92 (7%)
 Frame = +3

Query: 381  NMMREAAEVAQADRANLWHQICATEDENIRLREEMDMDQTKFTNE----KAVLAQRLTES 548
            +++RE  E  Q  +A L   +     E  + + + + D  + T E    K  LAQRL E+
Sbjct: 1345 DLLREQYEEEQEAKAELQRALSKANSEVAQWKTKYETDAIQRTEELEEAKKKLAQRLQEA 1404

Query: 549  EATTGHLRSE---LKAEKDRHIREKKELSRQM 635
            E  T    S+   L+  K R   E ++L R +
Sbjct: 1405 EEKTETANSKCASLEKTKQRLQGEVEDLMRDL 1436

>MYH14_HUMAN (Q7Z406) Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle|
            myosin heavy chain IIc) (NMHC II-C)
          Length = 1995

 Score = 30.0 bits (66), Expect = 6.0
 Identities = 23/87 (26%), Positives = 36/87 (41%), Gaps = 10/87 (11%)
 Frame = +3

Query: 393  EAAEVAQADRANLWHQICATEDENIRLREEMDMDQTKF----------TNEKAVLAQRLT 542
            E  + AQA+  N+   +   E + IRL +E+   + +           T  K  L  R+ 
Sbjct: 1297 EKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVR 1356

Query: 543  ESEATTGHLRSELKAEKDRHIREKKEL 623
              EA    LR +L+ E     R  +EL
Sbjct: 1357 AMEAEAAGLREQLEEEAAARERAGREL 1383

>LVA_DROME (Q8MSS1) Protein lava lamp|
          Length = 2779

 Score = 30.0 bits (66), Expect = 6.0
 Identities = 23/82 (28%), Positives = 41/82 (50%)
 Frame = +3

Query: 396 AAEVAQADRANLWHQICATEDENIRLREEMDMDQTKFTNEKAVLAQRLTESEATTGHLRS 575
           +AE+A+     L +Q+   +  N  LR+++   Q K      +++QRL E EAT      
Sbjct: 367 SAELAK-QLQELTNQLADLQATNEELRQQVAA-QAKLQVTDEIVSQRLEELEATIAAQLL 424

Query: 576 ELKAEKDRHIREKKELSRQMRE 641
           EL+ +K     + +EL+ +  E
Sbjct: 425 ELQEQKSAMAAQNEELAEKTTE 446

>APOE_SAISC (Q28995) Apolipoprotein E (Apo-E) (Fragment)|
          Length = 107

 Score = 29.6 bits (65), Expect = 7.9
 Identities = 24/97 (24%), Positives = 47/97 (48%), Gaps = 6/97 (6%)
 Frame = +3

Query: 363 IARPVLNMMREAAEVAQADRANLWHQIC-ATEDENIRLREEMDMDQTKFTNE----KAVL 527
           + + +  +M E  +  +A ++ L  Q+    E+   RL +E+   Q +   +    ++ L
Sbjct: 5   VTQELTALMDETMKELKAYKSELEEQLSPVAEETRARLSKELQAAQARLGADMEDVRSRL 64

Query: 528 AQRLTESEATTGHLRSELKAEKDRHIRE-KKELSRQM 635
           AQ  +E +A  G    EL+A    H+R+ +K L R +
Sbjct: 65  AQYRSEVQAMLGQSTDELRARLASHLRKLRKRLLRDV 101

>MSH6_ARATH (O04716) DNA mismatch repair protein MSH6-1 (AtMsh6-1)|
          Length = 1324

 Score = 29.6 bits (65), Expect = 7.9
 Identities = 13/64 (20%), Positives = 30/64 (46%)
 Frame = +3

Query: 426 NLWHQICATEDENIRLREEMDMDQTKFTNEKAVLAQRLTESEATTGHLRSELKAEKDRHI 605
           N+  ++C +E++++ L +E +MD+ +   EK     ++     T    R   +  K    
Sbjct: 229 NVGKEVCESEEDDVELVDENEMDEEELVEEKDEETSKVNRVSKTDSRKRKTSEVTKSGGE 288

Query: 606 REKK 617
           ++ K
Sbjct: 289 KKSK 292

>SMC_BACSU (P51834) Chromosome partition protein smc|
          Length = 1186

 Score = 29.6 bits (65), Expect = 7.9
 Identities = 22/84 (26%), Positives = 40/84 (47%), Gaps = 4/84 (4%)
 Frame = +3

Query: 387  MREAAEVAQADRANLWHQICATEDENIRLREEMD----MDQTKFTNEKAVLAQRLTESEA 554
            + E+ E  +  +  L  ++ A  ++  +L E++D      QT+ ++ K  L+  LTE + 
Sbjct: 759  LSESDEERKVRKRKLEEELSAVSEKMKQLEEDIDRLTKQKQTQ-SSTKESLSNELTELKI 817

Query: 555  TTGHLRSELKAEKDRHIREKKELS 626
                     K E+D   R KKEL+
Sbjct: 818  AAAKKEQACKGEEDNLARLKKELT 841

>CCHCR_PIG (Q9TSV3) Coiled-coil alpha-helical rod protein 1 (Alpha helical|
           coiled-coil rod protein) (Fragment)
          Length = 427

 Score = 29.6 bits (65), Expect = 7.9
 Identities = 23/85 (27%), Positives = 39/85 (45%)
 Frame = +3

Query: 387 MREAAEVAQADRANLWHQICATEDENIRLREEMDMDQTKFTNEKAVLAQRLTESEATTGH 566
           +   AE+ Q    +L H +C  E+E  R  +  D  + +FT +   L +R  E       
Sbjct: 283 LHTTAELLQVRVQSLTHILCIQEEELARKVQPSDCLEPEFTRKCQALLKRWREKVFA--- 339

Query: 567 LRSELKAEKDRHIREKKELSRQMRE 641
           L  +LKA++  H    ++L  Q+ E
Sbjct: 340 LMVQLKAQELEHRGCVEQLKGQVAE 364

>PFL_STRMU (Q59934) Formate acetyltransferase (EC 2.3.1.54) (Pyruvate|
           formate-lyase)
          Length = 775

 Score = 29.6 bits (65), Expect = 7.9
 Identities = 11/31 (35%), Positives = 21/31 (67%)
 Frame = +3

Query: 399 AEVAQADRANLWHQICATEDENIRLREEMDM 491
           A+    ++ N W+ I   ++E+IRLREE+++
Sbjct: 190 ADYLMQEKVNDWNSIAEIDEESIRLREEINL 220

>CCD43_RAT (Q5BK07) Coiled-coil domain-containing protein 43|
          Length = 222

 Score = 29.6 bits (65), Expect = 7.9
 Identities = 45/198 (22%), Positives = 82/198 (41%), Gaps = 14/198 (7%)
 Frame = +3

Query: 90  LDGQFEPSPIQEGEFTSVLALGEVLSLSTSARVQDFVRMLYAIMFKIYAEDHYRCRFLKG 269
           LDG+ E   + +  + +      +L +      ++ +  L  I+     ED       K 
Sbjct: 24  LDGRLEALGVDQAVYRAY-----ILGVLQEEEEEEKLDALQGILSAFLEEDSL-LDICKE 77

Query: 270 LVDRATNTSDNCREVDIDMDV---LVFLVKEEFGIARPVLNMMREAAEVAQADRANLWHQ 440
           +V+R + T D   +V  + +V      + K+   + +P     R  +E  +  +A L  Q
Sbjct: 78  IVERWSETRDVTTKVKKEDEVQAITTLIEKQAQIVVKP-----RVVSEEEKQRKAALLAQ 132

Query: 441 ICATEDENIRLREEMD---------MDQTKF--TNEKAVLAQRLTESEATTGHLRSELKA 587
                DE     E+ D          D++ F  TN + VL  R  E ++      S+ K 
Sbjct: 133 YADVTDEEDEADEKADPGASTANIGSDKSLFRNTNVEDVLNARKLERDSLRDE--SQRKK 190

Query: 588 EKDRHIREKKELSRQMRE 641
           E+D+  REK +L++Q R+
Sbjct: 191 EQDKLQREKDKLAKQERK 208

>CP51A_PONPY (Q5RE72) Cytochrome P450 51A1 (EC 1.14.13.70) (CYPLI) (P450LI)|
           (Sterol 14-alpha demethylase) (Lanosterol 14-alpha
           demethylase) (LDM) (P450-14DM) (P45014DM)
          Length = 503

 Score = 29.6 bits (65), Expect = 7.9
 Identities = 36/163 (22%), Positives = 66/163 (40%), Gaps = 11/163 (6%)
 Frame = +3

Query: 81  QVLLDGQFEPS-PIQEGEFTSVLA----LGEVLSLSTSARVQDFVRMLYAIMFKIYAEDH 245
           Q LLD  ++   P+ + E   +L      G+  S +TSA +  F+     +  K Y E  
Sbjct: 283 QTLLDATYKDGRPLTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQEKCYLEQK 342

Query: 246 YRCRFLKGLVDRATNTSDNCREVDIDMDVLVFLVKEEFGIARPVLNMMREA--AEVAQAD 419
             C       +    T D  +    D+++L   +KE   +  P++ MMR A   +     
Sbjct: 343 TVCG-----ENLPPLTYDQLK----DLNLLDRCIKETLRLRPPIMIMMRMARTPQTVAGY 393

Query: 420 RANLWHQICATEDENIRLR----EEMDMDQTKFTNEKAVLAQR 536
                HQ+C +   N RL+    E +D +  ++  +     ++
Sbjct: 394 TIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPASGEK 436

>CP51A_HUMAN (Q16850) Cytochrome P450 51A1 (EC 1.14.13.70) (CYPLI) (P450LI)|
           (Sterol 14-alpha demethylase) (Lanosterol 14-alpha
           demethylase) (LDM) (P450-14DM) (P45014DM)
          Length = 503

 Score = 29.6 bits (65), Expect = 7.9
 Identities = 36/163 (22%), Positives = 66/163 (40%), Gaps = 11/163 (6%)
 Frame = +3

Query: 81  QVLLDGQFEPS-PIQEGEFTSVLA----LGEVLSLSTSARVQDFVRMLYAIMFKIYAEDH 245
           Q LLD  ++   P+ + E   +L      G+  S +TSA +  F+     +  K Y E  
Sbjct: 283 QTLLDATYKDGRPLTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQKKCYLEQK 342

Query: 246 YRCRFLKGLVDRATNTSDNCREVDIDMDVLVFLVKEEFGIARPVLNMMREA--AEVAQAD 419
             C       +    T D  +    D+++L   +KE   +  P++ MMR A   +     
Sbjct: 343 TVCG-----ENLPPLTYDQLK----DLNLLDRCIKETLRLRPPIMIMMRMARTPQTVAGY 393

Query: 420 RANLWHQICATEDENIRLR----EEMDMDQTKFTNEKAVLAQR 536
                HQ+C +   N RL+    E +D +  ++  +     ++
Sbjct: 394 TIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPASGEK 436


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 86,964,797
Number of Sequences: 219361
Number of extensions: 1686357
Number of successful extensions: 4808
Number of sequences better than 10.0: 34
Number of HSP's better than 10.0 without gapping: 4651
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4805
length of database: 80,573,946
effective HSP length: 108
effective length of database: 56,882,958
effective search space used: 5972710590
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)