ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bags29a18 |
|---|---|
| Clone Library Name | barley_pub |
>MCM2_DROME (P49735) DNA replication licensing factor Mcm2 (Minichromosome| maintenance 2 protein) (DmMCM2) Length = 887 Score = 277 bits (709), Expect = 2e-74 Identities = 134/203 (66%), Positives = 160/203 (78%) Frame = +1 Query: 1 GVVTRRXGVFPQLQQVKYDCSKCGTVLGPFFQNSYTEVRVGSCPECQSKGPFTVNIEQTI 180 GVVT GV PQL +KYDC KCG VLGPF Q+ TE++ GSCPECQS GPF++N+EQT+ Sbjct: 295 GVVTATTGVLPQLSVIKYDCVKCGYVLGPFVQSQNTEIKPGSCPECQSTGPFSINMEQTL 354 Query: 181 YRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVTGIYTNNFDLSLNTK 360 YRNYQK+TLQESPG +PAGR+PR K+VILL DL D +PG+E+EVTGIYTNN+D SLNT Sbjct: 355 YRNYQKITLQESPGRIPAGRIPRSKDVILLADLCDQCKPGDELEVTGIYTNNYDGSLNTD 414 Query: 361 NGFPVFATVVEANYVSKKQDLFSAYKLTDEDKAEIEKLSKDPRISERIVKSIAPSIYGHE 540 GFPVFATV+ AN+V K LTDED A I+KLSKDPRI ER+V S+APSIYGH+ Sbjct: 415 QGFPVFATVIIANHVVVKDSKQVVQSLTDEDIATIQKLSKDPRIVERVVASMAPSIYGHD 474 Query: 541 DIKTAIALAMFGGQEKNVKGKHR 609 IK A+ALA+FGG+ KN KH+ Sbjct: 475 YIKRALALALFGGESKNPGEKHK 497
>MCM2_SCHPO (P40377) DNA replication licensing factor mcm2 (Minichromosome| maintenance protein 2) (Cell division control protein 19) Length = 830 Score = 276 bits (707), Expect = 3e-74 Identities = 128/209 (61%), Positives = 164/209 (78%), Gaps = 6/209 (2%) Frame = +1 Query: 1 GVVTRRXGVFPQLQQVKYDCSKCGTVLGPFFQNSYTEVRVGSCPECQSKGPFTVNIEQTI 180 GVVTRR G+FPQL+ +++ C+KCG LGPFFQ+S EV++ C C S+GPF +N E+T+ Sbjct: 315 GVVTRRTGLFPQLKYIRFTCTKCGATLGPFFQDSSVEVKISFCHNCSSRGPFVINSERTV 374 Query: 181 YRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVTGIYTNNFDLSLNTK 360 Y NYQ++TLQESPG VP+GRLPR++EVILL DL+D A+PGEEI+VTGIY NNFD SLNTK Sbjct: 375 YNNYQRITLQESPGTVPSGRLPRHREVILLADLVDVAKPGEEIDVTGIYRNNFDASLNTK 434 Query: 361 NGFPVFATVVEANYVSK------KQDLFSAYKLTDEDKAEIEKLSKDPRISERIVKSIAP 522 NGFPVFAT++EAN++S+ D FS +LTD+++ EI L+K P I RI+ S+AP Sbjct: 435 NGFPVFATIIEANHISQLDGSGNTDDDFSLSRLTDDEEREIRALAKSPDIHNRIIASMAP 494 Query: 523 SIYGHEDIKTAIALAMFGGQEKNVKGKHR 609 SIYGH IKTAIA A+FGG KN+ GKH+ Sbjct: 495 SIYGHRSIKTAIAAALFGGVPKNINGKHK 523
>MCM2_XENLA (P55861) DNA replication licensing factor MCM2 (x.MCM2)| Length = 886 Score = 273 bits (698), Expect = 3e-73 Identities = 131/203 (64%), Positives = 159/203 (78%) Frame = +1 Query: 1 GVVTRRXGVFPQLQQVKYDCSKCGTVLGPFFQNSYTEVRVGSCPECQSKGPFTVNIEQTI 180 GVVT GV PQL VKY+C+KC +LGPFFQ+ EVR GSCPECQS GPF +N+E+T+ Sbjct: 295 GVVTCCTGVLPQLSMVKYNCNKCNFILGPFFQSQNQEVRPGSCPECQSFGPFEINMEETV 354 Query: 181 YRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVTGIYTNNFDLSLNTK 360 Y+NYQ++T+QESPG V AGRLPR K+ ILL DL+D +PG+EIE+TGIY NN+D SLNT Sbjct: 355 YQNYQRITIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNTA 414 Query: 361 NGFPVFATVVEANYVSKKQDLFSAYKLTDEDKAEIEKLSKDPRISERIVKSIAPSIYGHE 540 NGFPVFATV+ AN+++KK D + +LTDED I LSKD RI ERI SIAPSIYGHE Sbjct: 415 NGFPVFATVILANHITKKDDKVAVRELTDEDVKAIVALSKDERIGERIFASIAPSIYGHE 474 Query: 541 DIKTAIALAMFGGQEKNVKGKHR 609 DIK +ALA+FGG+ KN GKH+ Sbjct: 475 DIKRGLALALFGGEAKNPGGKHK 497
>MCM2_YEAST (P29469) DNA replication licensing factor MCM2 (Minichromosome| maintenance protein 2) Length = 868 Score = 266 bits (681), Expect = 3e-71 Identities = 122/210 (58%), Positives = 164/210 (78%), Gaps = 8/210 (3%) Frame = +1 Query: 1 GVVTRRXGVFPQLQQVKYDCSKCGTVLGPFFQNSYTEVRVGSCPECQSKGPFTVNIEQTI 180 GVVTRR GVFPQL+ VK++C KCG++LGPFFQ+S E+R+ C C+SKGPF VN E+T+ Sbjct: 322 GVVTRRTGVFPQLKYVKFNCLKCGSILGPFFQDSNEEIRISFCTNCKSKGPFRVNGEKTV 381 Query: 181 YRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVTGIYTNNFDLSLNTK 360 YRNYQ++TLQE+PG VP GRLPR++EVILL DL+D ++PGEE+EVTGIY NN+D +LN K Sbjct: 382 YRNYQRVTLQEAPGTVPPGRLPRHREVILLADLVDVSKPGEEVEVTGIYKNNYDGNLNAK 441 Query: 361 NGFPVFATVVEANYVSKK--------QDLFSAYKLTDEDKAEIEKLSKDPRISERIVKSI 516 NGFPVFAT++EAN + ++ ++ + T+E++ E K+S+D I ++I+ S+ Sbjct: 442 NGFPVFATIIEANSIKRREGNTANEGEEGLDVFSWTEEEEREFRKISRDRGIIDKIISSM 501 Query: 517 APSIYGHEDIKTAIALAMFGGQEKNVKGKH 606 APSIYGH DIKTA+A ++FGG KNV GKH Sbjct: 502 APSIYGHRDIKTAVACSLFGGVPKNVNGKH 531
>MCM2_HUMAN (P49736) DNA replication licensing factor MCM2 (Minichromosome| maintenance protein 2 homolog) (Nuclear protein BM28) Length = 904 Score = 265 bits (677), Expect = 8e-71 Identities = 129/203 (63%), Positives = 157/203 (77%) Frame = +1 Query: 1 GVVTRRXGVFPQLQQVKYDCSKCGTVLGPFFQNSYTEVRVGSCPECQSKGPFTVNIEQTI 180 GVVT GV PQL VKY+C+KC VLGPF Q+ EV+ GSCPECQS GPF VN+E+TI Sbjct: 310 GVVTSCTGVLPQLSMVKYNCNKCNFVLGPFCQSQNQEVKPGSCPECQSAGPFEVNMEETI 369 Query: 181 YRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVTGIYTNNFDLSLNTK 360 Y+NYQ++ +QESPG V AGRLPR K+ ILL DL+D +PG+EIE+TGIY NN+D SLNT Sbjct: 370 YQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNTA 429 Query: 361 NGFPVFATVVEANYVSKKQDLFSAYKLTDEDKAEIEKLSKDPRISERIVKSIAPSIYGHE 540 NGFPVFATV+ AN+V+KK + + +LTDED I LSKD +I E+I SIAPSIYGHE Sbjct: 430 NGFPVFATVILANHVAKKDNKVAVGELTDEDVKMITSLSKDQQIGEKIFASIAPSIYGHE 489 Query: 541 DIKTAIALAMFGGQEKNVKGKHR 609 DIK +ALA+FGG+ KN GKH+ Sbjct: 490 DIKRGLALALFGGEPKNPGGKHK 512
>MCM2_MOUSE (P97310) DNA replication licensing factor MCM2 (Minichromosome| maintenance protein 2 homolog) (Nuclear protein BM28) Length = 904 Score = 265 bits (676), Expect = 1e-70 Identities = 128/203 (63%), Positives = 157/203 (77%) Frame = +1 Query: 1 GVVTRRXGVFPQLQQVKYDCSKCGTVLGPFFQNSYTEVRVGSCPECQSKGPFTVNIEQTI 180 GVVT GV PQL VKY+CSKC VLGPF Q+ EV+ GSCPECQS GPF +N+E+TI Sbjct: 310 GVVTSCTGVLPQLSMVKYNCSKCNFVLGPFCQSQNQEVKPGSCPECQSAGPFEINMEETI 369 Query: 181 YRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVTGIYTNNFDLSLNTK 360 Y+NYQ++ +QESPG V AGRLPR K+ ILL DL+D +PG+EIE+TGIY NN+D SLNT Sbjct: 370 YQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNTA 429 Query: 361 NGFPVFATVVEANYVSKKQDLFSAYKLTDEDKAEIEKLSKDPRISERIVKSIAPSIYGHE 540 NGFPVFAT++ AN+V+KK + + +LTDED I LSKD +I E+I SIAPSIYGHE Sbjct: 430 NGFPVFATIILANHVAKKDNKVAVGELTDEDVKMITGLSKDQQIGEKIFASIAPSIYGHE 489 Query: 541 DIKTAIALAMFGGQEKNVKGKHR 609 DIK +ALA+FGG+ KN GKH+ Sbjct: 490 DIKRGLALALFGGEPKNPGGKHK 512
>MCM_SULSO (Q9UXG1) Minichromosome maintenance protein MCM (EC 3.-.-.-)| Length = 686 Score = 123 bits (309), Expect = 4e-28 Identities = 64/154 (41%), Positives = 98/154 (63%) Frame = +1 Query: 127 CPECQSKGPFTVNIEQTIYRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEE 306 CP+C G F + E+T ++QK +QE P VP+G+LPR E+IL +DL+D ARPG+ Sbjct: 171 CPKCGKPGQFRLIPEKTKLIDWQKAVIQERPEEVPSGQLPRQLEIILEDDLVDSARPGDR 230 Query: 307 IEVTGIYTNNFDLSLNTKNGFPVFATVVEANYVSKKQDLFSAYKLTDEDKAEIEKLSKDP 486 ++VTGI D + + VF ++ + + Q + +++ED+ +I+ L+KDP Sbjct: 231 VKVTGILDIKQDSPVK-RGSRAVFDIYMKVSSIEVSQKVLDEVIISEEDEKKIKDLAKDP 289 Query: 487 RISERIVKSIAPSIYGHEDIKTAIALAMFGGQEK 588 I +RI+ SIAPSIYGH ++K A+ALA+FGG K Sbjct: 290 WIRDRIISSIAPSIYGHWELKEALALALFGGVPK 323
>MCM3_YEAST (P24279) DNA replication licensing factor MCM3 (Minichromosome| maintenance protein 3) Length = 971 Score = 100 bits (250), Expect = 3e-21 Identities = 71/219 (32%), Positives = 114/219 (52%), Gaps = 17/219 (7%) Frame = +1 Query: 1 GVVTRRXGVFPQLQQVKYDCSKCGTVLGPFFQNSYTEVRV---------GSCPECQSKG- 150 G+VT+ V P+L + + +K G F YT+ P ++G Sbjct: 184 GIVTKTSLVRPKLIRSVHYAAKTGR----FHYRDYTDATTTLTTRIPTPAIYPTEDTEGN 239 Query: 151 PFTVNIEQTIYRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVTGIYT 330 T + + ++Q++T+QE P + PAG+LPR +VIL +DL+D +PG+ + V G++ Sbjct: 240 KLTTEYGYSTFIDHQRITVQEMPEMAPAGQLPRSIDVILDDDLVDKTKPGDRVNVVGVFK 299 Query: 331 NNFDLSLNTKNGFPV--FATVVEANYV----SKKQDLFSAYKLTDEDKAEIEKLSKDPRI 492 + +N N + F T++ N V ++ + + LTD D I KLSK I Sbjct: 300 SLGAGGMNQSNSNTLIGFKTLILGNTVYPLHARSTGVAARQMLTDFDIRNINKLSKKKDI 359 Query: 493 SERIVKSIAPSIYGHEDIKTAIALAMFGGQEKNVK-GKH 606 + + +S+APSIYGH+ IK AI L + GG EKN++ G H Sbjct: 360 FDILSQSLAPSIYGHDHIKKAILLMLMGGVEKNLENGSH 398
>MCM4_HUMAN (P33991) DNA replication licensing factor MCM4 (CDC21 homolog)| (P1-CDC21) Length = 863 Score = 97.4 bits (241), Expect = 3e-20 Identities = 67/217 (30%), Positives = 107/217 (49%), Gaps = 14/217 (6%) Frame = +1 Query: 1 GVVTRRXGVFPQLQQVKYDCSKCG-TVLGPFFQNSYTEVRVGSCPECQSKGPFTVNIEQT 177 G+V R + P++Q+ + C C T + E V C C + + ++ Sbjct: 287 GMVIRTSQLIPEMQEAFFQCQVCAHTTRVEMDRGRIAEPSV--CGRCHTTHSMALIHNRS 344 Query: 178 IYRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVTGIY-TNNFDLSLN 354 ++ + Q + LQESP +PAG+ P + NDL+D +PG+ + VTGIY ++ Sbjct: 345 LFSDKQMIKLQESPEDMPAGQTPHTVILFAHNDLVDKVQPGDRVNVTGIYRAVPIRVNPR 404 Query: 355 TKNGFPVFATVVEANYVSKKQ-------DLFSAYKLTDEDKAE-IEKLSKDPRISERIVK 510 N V+ T ++ + K D + KL E + E +++LS+ P I ER+ Sbjct: 405 VSNVKSVYKTHIDVIHYRKTDAKRLHGLDEEAEQKLFSEKRVELLKELSRKPDIYERLAS 464 Query: 511 SIAPSIYGHEDIKTAIALAMFGGQEKNV----KGKHR 609 ++APSIY HEDIK I L +FGG K+ +GK R Sbjct: 465 ALAPSIYEHEDIKKGILLQLFGGTRKDFSHTGRGKFR 501
>MCM7_SCHPO (O75001) DNA replication licensing factor mcm7 (Minichromosome| maintenance protein 7) Length = 760 Score = 96.3 bits (238), Expect = 6e-20 Identities = 58/202 (28%), Positives = 100/202 (49%), Gaps = 4/202 (1%) Frame = +1 Query: 1 GVVTRRXGVFPQLQQVKYDCSKCG-TVLGPFFQNSY---TEVRVGSCPECQSKGPFTVNI 168 G+VTR V P L Y C +CG V Q ++ +E C + +KG ++ Sbjct: 186 GIVTRTSDVKPSLTVNAYTCDRCGYEVFQEIRQKTFLPMSECPSDECKKNDAKGQLFMST 245 Query: 169 EQTIYRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVTGIYTNNFDLS 348 + + +Q++ +QE VP G +PR V L + PG+ ++++GI+ Sbjct: 246 RASKFLPFQEVKIQELTNQVPIGHIPRSLTVHLYGAITRSVNPGDIVDISGIFLPTPYTG 305 Query: 349 LNTKNGFPVFATVVEANYVSKKQDLFSAYKLTDEDKAEIEKLSKDPRISERIVKSIAPSI 528 + T +E +YVS+ ++ + T + +A I +L++ + E++ KSIAP I Sbjct: 306 FRAMRAGLLTDTYLECHYVSQIIKNYTNIEKTPQSEAAIAELNQGGNVYEKLAKSIAPEI 365 Query: 529 YGHEDIKTAIALAMFGGQEKNV 594 YGHED+K A+ L + GG K + Sbjct: 366 YGHEDVKKALLLLLVGGVTKEL 387
>CDC47_YEAST (P38132) DNA replication licensing factor CDC47 (Cell division| control protein 47) Length = 845 Score = 95.5 bits (236), Expect = 1e-19 Identities = 56/202 (27%), Positives = 101/202 (50%), Gaps = 4/202 (1%) Frame = +1 Query: 1 GVVTRRXGVFPQLQQVKYDCSKCG-TVLGPFFQNSYTEVRVGSCPEC---QSKGPFTVNI 168 G++TR V P ++ + Y C +CG V ++T + + EC Q+KG ++ Sbjct: 243 GIITRVSDVKPAVEVIAYTCDQCGYEVFQEVNSRTFTPLSECTSEECSQNQTKGQLFMST 302 Query: 169 EQTIYRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVTGIYTNNFDLS 348 + + +Q+ +QE VP G +PR + + L+ PG+ ++VTGI+ Sbjct: 303 RASKFSAFQECKIQELSQQVPVGHIPRSLNIHVNGTLVRSLSPGDIVDVTGIFLPAPYTG 362 Query: 349 LNTKNGFPVFATVVEANYVSKKQDLFSAYKLTDEDKAEIEKLSKDPRISERIVKSIAPSI 528 + T +EA +V + + F+++ LT + + + +L + R+ KSIAP I Sbjct: 363 FKALKAGLLTETYLEAQFVRQHKKKFASFSLTSDVEERVMELITSGDVYNRLAKSIAPEI 422 Query: 529 YGHEDIKTAIALAMFGGQEKNV 594 YG+ D+K A+ L + GG +K V Sbjct: 423 YGNLDVKKALLLLLVGGVDKRV 444
>MCM4_MOUSE (P49717) DNA replication licensing factor MCM4 (CDC21 homolog)| (P1-CDC21) Length = 862 Score = 95.5 bits (236), Expect = 1e-19 Identities = 66/222 (29%), Positives = 107/222 (48%), Gaps = 19/222 (8%) Frame = +1 Query: 1 GVVTRRXGVFPQLQQVKYDCSKCGTVLGPFFQNSYTEVRVG------SCPECQSKGPFTV 162 G+V R + P++Q+ + C C + E+ G SC C + + Sbjct: 286 GMVIRTSQLIPEMQEAFFQCQVCA-------HTTRVEIDRGRIAEPCSCVHCHTTHSMAL 338 Query: 163 NIEQTIYRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVTGIY-TNNF 339 ++ + + Q + LQESP +PAG+ P + NDL+D +PG+ + VTGIY Sbjct: 339 IHNRSFFSDKQMIKLQESPEDMPAGQTPHTIVLFAHNDLVDKVQPGDRVNVTGIYRAVPI 398 Query: 340 DLSLNTKNGFPVFATVVEANYVSKKQ-------DLFSAYKLTDEDKAE-IEKLSKDPRIS 495 ++ N V+ T ++ + K D + KL E + + +++LS+ P I Sbjct: 399 RVNPRVSNVKSVYKTHIDVIHYRKTDAKRLHGLDEEAEQKLFSEKRVKLLKELSRKPDIY 458 Query: 496 ERIVKSIAPSIYGHEDIKTAIALAMFGGQEKNV----KGKHR 609 ER+ ++APSIY HEDIK I L +FGG K+ +GK R Sbjct: 459 ERLASALAPSIYEHEDIKKGILLQLFGGTRKDFSHTGRGKFR 500
>MCM4_XENLA (P30664) DNA replication licensing factor MCM4 (CDC21 homolog)| (P1-CDC21) (x.MCM4) Length = 863 Score = 95.1 bits (235), Expect = 1e-19 Identities = 67/217 (30%), Positives = 108/217 (49%), Gaps = 14/217 (6%) Frame = +1 Query: 1 GVVTRRXGVFPQLQQVKYDCSKCG-TVLGPFFQNSYTEVRVGSCPECQSKGPFTVNIEQT 177 G+V R + P++Q+ + C C T + E V C C + + ++ Sbjct: 287 GMVIRTSQIIPEMQEAFFKCQVCAFTTRVEIDRGRIAEPSV--CKHCNTTHSMALIHNRS 344 Query: 178 IYRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVTGIYTN-NFDLSLN 354 ++ + Q + LQESP +PAG+ P + NDL+D +PG+ + VTGIY ++ Sbjct: 345 MFSDKQMIKLQESPEDMPAGQTPHTTILYGHNDLVDKVQPGDRVNVTGIYRAVPIRVNPR 404 Query: 355 TKNGFPVFATVVEANYVSKKQ-------DLFSAYKL-TDEDKAEIEKLSKDPRISERIVK 510 +N V+ T ++ + K D + KL T+E A +++L+ P I ER+ Sbjct: 405 VRNVKSVYKTHIDVIHYRKTDSKRLHGIDEDTEQKLFTEERVAMLKELAAKPDIYERLAA 464 Query: 511 SIAPSIYGHEDIKTAIALAMFGGQEKNV----KGKHR 609 ++APSIY HEDIK I L +FGG K+ +GK R Sbjct: 465 ALAPSIYEHEDIKKGILLQLFGGTRKDFSHTGRGKFR 501
>MCM3_ARATH (Q9FL33) DNA replication licensing factor MCM3 homolog| (Minichromosome maintenance protein 3 homolog) Length = 776 Score = 95.1 bits (235), Expect = 1e-19 Identities = 68/207 (32%), Positives = 108/207 (52%), Gaps = 5/207 (2%) Frame = +1 Query: 1 GVVTRRXGVFPQLQQVKYDCSKCGTVLGPFFQN--SYTEVRVGSC-PECQSKGPFTVNIE 171 G+VT+ V P++ + + C G +++ S+ + GS P KG V Sbjct: 120 GIVTKCSLVRPKVVKSVHFCPSTGEFTNRDYRDITSHAGLPTGSVYPTRDDKGNLLVTEY 179 Query: 172 QTI-YRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVTGIYTNNFDLS 348 Y+++Q L++QE P G+LPR +VI +DL+D +PG+ + V GIY S Sbjct: 180 GLCKYKDHQTLSIQEVPENAAPGQLPRSVDVIAEDDLVDSCKPGDRVSVFGIYKALPGKS 239 Query: 349 LNTKNGFPVFATVVEANYVSKKQDLFSAYKLTDEDKAEIEKLSKDPRISERIVKSIAPSI 528 + NG VF T++ AN ++ +A T +D I+ +++ + + +S+APSI Sbjct: 240 KGSVNG--VFRTILIANNIALLNKEANAPIYTKQDLDNIKNIARRDDAFDLLARSLAPSI 297 Query: 529 YGHEDIKTAIALAMFGGQEKNVK-GKH 606 YGH IK A+ L M GG EKN+K G H Sbjct: 298 YGHAWIKKAVVLLMLGGVEKNLKNGTH 324
>MCM3_MAIZE (Q43704) DNA replication licensing factor MCM3 homolog (Replication| origin activator) (ROA protein) (Fragment) Length = 600 Score = 94.7 bits (234), Expect = 2e-19 Identities = 56/143 (39%), Positives = 85/143 (59%), Gaps = 1/143 (0%) Frame = +1 Query: 181 YRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVTGIYTNNFDLSLNTK 360 Y+++Q L++QE P G+LPR +VI+ +DL+DC +PG+ + + G+Y S + Sbjct: 21 YKDHQTLSMQEVPENSAPGQLPRTVDVIVEDDLVDCCKPGDRVSIVGVYKALPGKSKGSV 80 Query: 361 NGFPVFATVVEANYVSKKQDLFSAYKLTDEDKAEIEKLSKDPRISERIVKSIAPSIYGHE 540 +G VF TV+ AN VS +A T ED ++++S+ + + S+APSIYGH Sbjct: 81 SG--VFRTVLIANNVSLLNKEANAPVYTREDLKRMKEISRRNDTFDLLGNSLAPSIYGHL 138 Query: 541 DIKTAIALAMFGGQEKNVK-GKH 606 IK A+ L M GG EKN+K G H Sbjct: 139 WIKKAVVLLMLGGVEKNLKNGTH 161
>MCM3_SCHPO (P30666) DNA replication licensing factor mcm3 (Minichromosome| maintenance protein 3) Length = 879 Score = 93.6 bits (231), Expect = 4e-19 Identities = 57/164 (34%), Positives = 91/164 (55%), Gaps = 8/164 (4%) Frame = +1 Query: 139 QSKGPFTVNIEQTIYRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVT 318 ++ P ++ + +R++Q ++LQE P P G+LPR +++L +DL+D +PG+ + + Sbjct: 184 ENGNPLSIEFGFSTFRDHQSISLQEMPERAPPGQLPRSIDILLDDDLVDTVKPGDRVNIV 243 Query: 319 GIYTNNFDLSLNTKNGFPVFATVVEANYV---SKKQDLFS----AYKLTDEDKAEIEKLS 477 G Y + S + N F TV+ AN V K L + A +TD D I KL+ Sbjct: 244 GQYRSMG--SKTSGNTSATFRTVLLANNVVLLGNKPGLGNVGGGALDITDADIRNINKLA 301 Query: 478 KDPRISERIVKSIAPSIYGHEDIKTAIALAMFGGQEKNV-KGKH 606 + + E + S+APSIYG+E +K AI L + GG EKN+ G H Sbjct: 302 RKKNVFELLSTSLAPSIYGYEYVKQAILLLLLGGTEKNLTNGTH 345
>MCM3_HUMAN (P25205) DNA replication licensing factor MCM3 (DNA polymerase| alpha holoenzyme-associated protein P1) (RLF beta subunit) (P102 protein) (P1-MCM3) Length = 808 Score = 91.7 bits (226), Expect = 2e-18 Identities = 67/211 (31%), Positives = 111/211 (52%), Gaps = 9/211 (4%) Frame = +1 Query: 1 GVVTRRXGVFPQLQQVKYDCSKCGTVLGPFFQNSYTEVRVGSCPECQSK----GPFTVNI 168 G+VT+ V P++ + + C + + + T V S +K P Sbjct: 129 GIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSSSVYPTKDEENNPLETEY 188 Query: 169 EQTIYRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVTGIYTNNFDLS 348 ++Y+++Q +T+QE P PAG+LPR +VIL +DL+D A+PG+ ++V G Y Sbjct: 189 GLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGTYR----CL 244 Query: 349 LNTKNGFP--VFATVVEANYVSKKQDLFSAYKLTDEDKAEIEKLSK--DPRISERIVKSI 516 K G+ F TV+ A V K+ + + ED A+I+K SK I +++ KS+ Sbjct: 245 PGKKGGYTSGTFRTVLIACNV-KQMSKDAQPSFSAEDIAKIKKFSKTRSKDIFDQLAKSL 303 Query: 517 APSIYGHEDIKTAIALAMFGGQEKNVK-GKH 606 APSI+GH+ +K AI + GG E++++ G H Sbjct: 304 APSIHGHDYVKKAILCLLLGGVERDLENGSH 334
>MCM3_MOUSE (P25206) DNA replication licensing factor MCM3 (DNA polymerase| alpha holoenzyme-associated protein P1) (P1-MCM3) Length = 812 Score = 89.4 bits (220), Expect = 8e-18 Identities = 64/213 (30%), Positives = 109/213 (51%), Gaps = 11/213 (5%) Frame = +1 Query: 1 GVVTRRXGVFPQLQQVKYDCSKCGTVLGPFFQNSYTEVRVGSCPECQSK----GPFTVNI 168 G+VT+ V P++ + + C + + + T V S +K P Sbjct: 129 GIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSSSVYPTKDEENNPLETEY 188 Query: 169 EQTIYRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVTGIYTNNFDLS 348 ++Y+++Q +T+QE P PAG+LPR +VIL +DL+D +PG+ I+V G Y Sbjct: 189 GLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKVKPGDRIQVVGTYR-----C 243 Query: 349 LNTKNGFPVFAT----VVEANYVSKKQDLFSAYKLTDEDKAEIEKLSK--DPRISERIVK 510 L K G T ++ N +D+ A+ + +D A+I+K SK + E++ + Sbjct: 244 LPGKKGCYTSGTFRTVLIACNVKQMSKDIQPAF--SADDIAKIKKFSKTRSKDVFEQLAR 301 Query: 511 SIAPSIYGHEDIKTAIALAMFGGQEKNVK-GKH 606 S+APSI+GH+ +K AI + GG E+ ++ G H Sbjct: 302 SLAPSIHGHDYVKKAILCLLLGGVERELENGSH 334
>MCM7_MOUSE (Q61881) DNA replication licensing factor MCM7 (CDC47 homolog)| Length = 719 Score = 88.2 bits (217), Expect = 2e-17 Identities = 63/209 (30%), Positives = 103/209 (49%), Gaps = 9/209 (4%) Frame = +1 Query: 1 GVVTRRXGVFPQLQQVKYDCSKCGTVLGPFFQNSYTEVRVGSCP--ECQ---SKGPFTVN 165 G+VTR V P++ Y C +CG Q S T + + CP ECQ S G + Sbjct: 165 GIVTRVSEVKPRMVVATYTCDQCGAETYQPIQ-SPTFMPLIMCPSQECQTNRSGGRLYLQ 223 Query: 166 IEQTIYRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVTGIYTNNFDL 345 + + +Q++ +QE VP G +PR V+L + A+PG+ + VTGI+ Sbjct: 224 TRGSKFVKFQEMKIQEHSDQVPVGNIPRSITVVLEGENTRIAQPGDHVSVTGIFLPVLRT 283 Query: 346 SLNTKNGFPVFATVVEANYVSKK----QDLFSAYKLTDEDKAEIEKLSKDPRISERIVKS 513 + T +EA+++ K D+ A +L+ E+ +I + E++ S Sbjct: 284 GFQQMAQGLLSETYLEAHWIVKMTKSDDDVSGAGELSSEELKQIA----EEDFYEKLAAS 339 Query: 514 IAPSIYGHEDIKTAIALAMFGGQEKNVKG 600 IAP IYGHED+K A+ L + GG +++ +G Sbjct: 340 IAPEIYGHEDVKKALLLLLVGGVDQSPQG 368
>MCM4_DROME (Q26454) DNA replication licensing factor MCM4 (Protein disc| proliferation abnormal) Length = 866 Score = 87.8 bits (216), Expect = 2e-17 Identities = 62/210 (29%), Positives = 103/210 (49%), Gaps = 14/210 (6%) Frame = +1 Query: 1 GVVTRRXGVFPQLQQVKYDCSKCGTVLGPFFQNSYTEVRVGS------CPECQSKGPFTV 162 G+V R V P++++ + C+ C ++ EV G C C + F + Sbjct: 290 GMVIRSSNVIPEMREAFFSCNICSF-------STTVEVDRGRINQPTLCTNCNTNHCFRL 342 Query: 163 NIEQTIYRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVTGIY----T 330 ++ + + Q + LQESP + AG+ P + NDL+D +PG+ + VTGIY Sbjct: 343 IHNRSEFTDKQLVKLQESPDDMAAGQTPHNVLLYAHNDLVDKVQPGDRVTVTGIYRATPL 402 Query: 331 NNFDLSLNTKNGFPVFATVVEANYVSKK---QDLFSAYKLTDEDKAE-IEKLSKDPRISE 498 LS + K+ + VV V K +D + ++ E ++ L+K P I + Sbjct: 403 KTGGLSSSVKSVYKTHVDVVHFRKVDNKRLYEDEEGKDHIFPPERVELLQLLAKKPDIYD 462 Query: 499 RIVKSIAPSIYGHEDIKTAIALAMFGGQEK 588 R+ ++IAPSIY ++DIK I L +FGG +K Sbjct: 463 RLARAIAPSIYENDDIKKGILLQLFGGTKK 492
>MCM3_ENTHI (Q24849) DNA replication licensing factor MCM3| Length = 597 Score = 87.8 bits (216), Expect = 2e-17 Identities = 60/196 (30%), Positives = 93/196 (47%) Frame = +1 Query: 1 GVVTRRXGVFPQLQQVKYDCSKCGTVLGPFFQNSYTEVRVGSCPECQSKGPFTVNIEQTI 180 G++T+ + P LQ C + S+ +V V + P + + Sbjct: 26 GIITKSSQIRPLLQTAVQFCPLDYSTHARDL--SHADVMVKLSSKTPDGKPLELEPGLST 83 Query: 181 YRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVTGIYTNNFDLSLNTK 360 Y+++Q L +QE P P G++PR VILL+ L+D +PG+ + + G +L Sbjct: 84 YKDFQTLVVQEMPESAPTGQMPRSVIVILLDQLVDKGKPGDRVIINGTLK-----ALAGP 138 Query: 361 NGFPVFATVVEANYVSKKQDLFSAYKLTDEDKAEIEKLSKDPRISERIVKSIAPSIYGHE 540 N F V+EA ++ Q +LT+ DK I+K+ K+ KSIAPSIYGH Sbjct: 139 NHSSTFKVVLEAENINTLQS--EGPELTEIDKENIKKVMKEENPINLFSKSIAPSIYGHS 196 Query: 541 DIKTAIALAMFGGQEK 588 D+K AI L + G K Sbjct: 197 DVKKAILLMLVGATPK 212
>MCM3_XENLA (P49739) DNA replication licensing factor MCM3 (x.MCM3) (P1| homolog) (P100) Length = 807 Score = 87.0 bits (214), Expect = 4e-17 Identities = 55/155 (35%), Positives = 84/155 (54%), Gaps = 5/155 (3%) Frame = +1 Query: 139 QSKGPFTVNIEQTIYRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVT 318 + P + Y+++Q L++QE P PAG+LPR ++I +DL+D +PG+ +++ Sbjct: 179 EENNPLETEYGLSTYKDHQTLSIQEMPEKAPAGQLPRSVDIIADDDLVDKCKPGDRVQIV 238 Query: 319 GIYTNNFDLSLNTKNG---FPVFATVVEANYVSKKQDLFSAYKLTDEDKAEIEKLSK--D 483 GIY L +K G F T++ AN + K A + +D A+I+K K Sbjct: 239 GIYR-----CLPSKQGGFTSGTFRTILLANNI-KLMSKEIAPTFSADDVAKIKKFCKAHS 292 Query: 484 PRISERIVKSIAPSIYGHEDIKTAIALAMFGGQEK 588 I E + KS+APSI+GHE IK AI + GG EK Sbjct: 293 KDIFEHLSKSLAPSIHGHEYIKKAILCMLLGGNEK 327
>MCM8_HUMAN (Q9UJA3) DNA replication licensing factor MCM8 (Minichromosome| maintenance 8) Length = 840 Score = 86.7 bits (213), Expect = 5e-17 Identities = 63/222 (28%), Positives = 106/222 (47%), Gaps = 19/222 (8%) Frame = +1 Query: 1 GVVTRRXGVFPQLQQVKYDCSKCGTVLG-PFFQNSYTEVRVGSCPECQSKGPFTV--NIE 171 G V R + P ++ + C+ CG + P Y+ P C+ + FT + Sbjct: 223 GTVVRVSNIKPLCTKMAFLCAACGEIQSFPLPDGKYSLPTKCPVPVCRGRS-FTALRSSP 281 Query: 172 QTIYRNYQKLTLQE--SPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVTGIY-TNNFD 342 T+ ++Q + +QE S AGR+PR E L++DL+D PG+ + +TGI +N + Sbjct: 282 LTVTMDWQSIKIQELMSDDQREAGRIPRTIECELVHDLVDSCVPGDTVTITGIVKVSNAE 341 Query: 343 LSLNTKNGFPVFATVVEANYVSK-------------KQDLFSAYKLTDEDKAEIEKLSKD 483 KN +F +EAN +S K + + L +D I+++ + Sbjct: 342 EGSRNKNDKCMFLLYIEANSISNSKGQKTKSSEDGCKHGMLMEFSL--KDLYAIQEIQAE 399 Query: 484 PRISERIVKSIAPSIYGHEDIKTAIALAMFGGQEKNVKGKHR 609 + + IV S+ P I+GHE +K +ALA+FGG +K K+R Sbjct: 400 ENLFKLIVNSLCPVIFGHELVKAGLALALFGGSQKYADDKNR 441
>MCM4_SCHPO (P29458) DNA replication licensing factor mcm4 (Minichromosome| maintenance protein 4) (Cell division control protein 21) Length = 931 Score = 85.5 bits (210), Expect = 1e-16 Identities = 61/222 (27%), Positives = 107/222 (48%), Gaps = 25/222 (11%) Frame = +1 Query: 1 GVVTRRXGVFPQLQQVKYDCSKCGTVLGPFFQNSYTEVRVGSCPE--CQSKGPFTVNIEQ 174 G+V R V P ++Q + CS CG + + CP C + + + Sbjct: 307 GLVLRCTPVIPDMKQAFFRCSVCGHCVTVEIDRGRIAEPI-KCPREVCGATNAMQLIHNR 365 Query: 175 TIYRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVTGIY-TNNFDLSL 351 + + + Q + LQE+P +VP G+ P + + ++L+D AR G+ IEVTGI+ L+ Sbjct: 366 SEFADKQVIKLQETPDVVPDGQTPHSVSLCVYDELVDSARAGDRIEVTGIFRCVPVRLNP 425 Query: 352 NTKNGFPVFATVVEANYVSKKQD----------------------LFSAYKLTDEDKAEI 465 + +F T V+ ++ KKQD + K++DE+ +I Sbjct: 426 RMRTVKSLFKTYVDVVHI-KKQDKRRLGTDPSTLESDIAEDAALQIDEVRKISDEEVEKI 484 Query: 466 EKLSKDPRISERIVKSIAPSIYGHEDIKTAIALAMFGGQEKN 591 +++SK I + + +S+APSIY +D+K + L +FGG K+ Sbjct: 485 QQVSKRDDIYDILSRSLAPSIYEMDDVKKGLLLQLFGGTNKS 526
>PROL_ARATH (P43299) PROLIFERA protein| Length = 716 Score = 85.5 bits (210), Expect = 1e-16 Identities = 57/208 (27%), Positives = 95/208 (45%), Gaps = 9/208 (4%) Frame = +1 Query: 1 GVVTRRXGVFPQLQQVKYDCSKCG---------TVLGPFFQNSYTEVRVGSCPECQSKGP 153 G+VTR V P + Y C CG V P F+ + R+ S G Sbjct: 159 GIVTRCSDVKPLMAVAVYTCEDCGHEIYQEVTSRVFMPLFKCPSSRCRLNS-----KAGN 213 Query: 154 FTVNIEQTIYRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVTGIYTN 333 + + + + +Q+ +QE VP G +PR V L +L PG+ +E +GI+ Sbjct: 214 PILQLRASKFLKFQEAKMQELAEHVPKGHIPRSMTVHLRGELTRKVSPGDVVEFSGIFLP 273 Query: 334 NFDLSLNTKNGFPVFATVVEANYVSKKQDLFSAYKLTDEDKAEIEKLSKDPRISERIVKS 513 V T +EA V+ + + Y+ +++ +I +L++D I ++ +S Sbjct: 274 IPYTGFKALRAGLVADTYLEATSVTHFKKKYEEYEFQKDEEEQIARLAEDGDIYNKLSRS 333 Query: 514 IAPSIYGHEDIKTAIALAMFGGQEKNVK 597 +AP IYGHEDIK A+ L + G + +K Sbjct: 334 LAPEIYGHEDIKKALLLLLVGAPHRQLK 361
>MCM8_MOUSE (Q9CWV1) DNA replication licensing factor MCM8 (Minichromosome| maintenance 8) Length = 833 Score = 85.1 bits (209), Expect = 1e-16 Identities = 64/227 (28%), Positives = 101/227 (44%), Gaps = 24/227 (10%) Frame = +1 Query: 1 GVVTRRXGVFPQLQQVKYDCSKCGTVLG-PFFQNSYTEVRVGSCPECQSKG-------PF 156 G V R + P + + C+ CG + P YT P C+ + P Sbjct: 216 GTVVRVSNIKPLCTNMAFQCAACGEIQSFPLPDGKYTLPTKCPVPACRGRSFAPLRSSPL 275 Query: 157 TVNIEQTIYRNYQKLTLQE--SPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVTGIY- 327 TV ++ +Q + +QE S AGR+PR E L++DL+D PG+ + VTGI Sbjct: 276 TVTLD------WQLIKIQELMSDAQREAGRIPRTIECELVHDLVDSCVPGDTVTVTGIVK 329 Query: 328 TNNFDLSLNTKNGFPVFATVVEANYVSK-------------KQDLFSAYKLTDEDKAEIE 468 +N + KN +F +EAN VS K + L +D I Sbjct: 330 VSNSEEGSRNKNDKCMFLLYIEANSVSNSKGPKAQTAEDGCKHGTLMEFSL--KDLYAIR 387 Query: 469 KLSKDPRISERIVKSIAPSIYGHEDIKTAIALAMFGGQEKNVKGKHR 609 ++ + + + +V S+ P I+GHE +K + LA+FGG +K K+R Sbjct: 388 EIQAEENLLKLVVNSLCPVIFGHELVKAGLTLALFGGSQKYADDKNR 434
>MCM7_HUMAN (P33993) DNA replication licensing factor MCM7 (CDC47 homolog)| (P1.1-MCM3) Length = 719 Score = 84.7 bits (208), Expect = 2e-16 Identities = 63/209 (30%), Positives = 102/209 (48%), Gaps = 9/209 (4%) Frame = +1 Query: 1 GVVTRRXGVFPQLQQVKYDCSKCGTVLGPFFQNSYTEVRVGSCP--ECQ---SKGPFTVN 165 G+VTR V P++ Y C +CG Q S T + + CP ECQ S G + Sbjct: 165 GIVTRVSEVKPKMVVATYTCDQCGAETYQPIQ-SPTFMPLIMCPSQECQTNRSGGRLYLQ 223 Query: 166 IEQTIYRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVTGIYTNNFDL 345 + + +Q++ +QE VP G +PR V++ + A+PG+ + VTGI+ Sbjct: 224 TRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRT 283 Query: 346 SLNTKNGFPVFATVVEANYVSK----KQDLFSAYKLTDEDKAEIEKLSKDPRISERIVKS 513 + T +EA+ + K + D A +LT E+ +I + E++ S Sbjct: 284 GFRQVVQGLLSETYLEAHRIVKMNKSEDDESGAGELTREELRQIA----EEDFYEKLAAS 339 Query: 514 IAPSIYGHEDIKTAIALAMFGGQEKNVKG 600 IAP IYGHED+K A+ L + GG +++ +G Sbjct: 340 IAPEIYGHEDVKKALLLLLVGGVDQSPRG 368
>MCM5_XENLA (P55862) DNA replication licensing factor MCM5 (CDC46 homolog)| (x.CDC46) Length = 735 Score = 83.2 bits (204), Expect = 5e-16 Identities = 60/214 (28%), Positives = 92/214 (42%), Gaps = 16/214 (7%) Frame = +1 Query: 1 GVVTRRXGVFPQLQQVKYDCSKCGTVLGPFFQNSYTE---------VRVGSCPECQSKGP 153 G++ V + ++ C C +G E P C P Sbjct: 154 GIIIAATAVRAKATKISIQCRSCRNTIGNIAVRPGLEGYAMPRKCNTEQAGRPNCPLD-P 212 Query: 154 FTVNIEQTIYRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVTGIYTN 333 + + ++ ++Q L LQESP VP G LPR+ ++ L D PG + + GIY+ Sbjct: 213 YFIIPDKCKCVDFQTLKLQESPDAVPHGELPRHMQLYCDRYLCDKVVPGNRVTIMGIYSI 272 Query: 334 NFDLSLNTKNGFPV-------FATVVEANYVSKKQDLFSAYKLTDEDKAEIEKLSKDPRI 492 +TK V + VV ++ +A +T +++ E +L+ P I Sbjct: 273 RKSGKTSTKGRDRVGVGIRSSYIRVVGIQVDTEGTGRSAAGAITPQEEEEFRRLAAKPDI 332 Query: 493 SERIVKSIAPSIYGHEDIKTAIALAMFGGQEKNV 594 E + KSIAPSIYG DIK AIA +FGG K + Sbjct: 333 YETVAKSIAPSIYGSSDIKKAIACLLFGGSRKRL 366
>MCM6_SCHPO (P49731) DNA replication licensing factor mcm6 (Minichromosome| maintenance protein 6) Length = 892 Score = 82.4 bits (202), Expect = 9e-16 Identities = 70/250 (28%), Positives = 108/250 (43%), Gaps = 54/250 (21%) Frame = +1 Query: 1 GVVTRRXGVFPQLQQVKYDCSKCGTVLGPFFQN-SYTEVRVGSCPE--CQSKGPFTVNIE 171 G VTR V P+L Q + C +C TV+ Q YTE CP C +K + +NI Sbjct: 214 GTVTRTSEVRPELAQGTFICEECHTVVSNVEQAFRYTEPT--QCPNELCANKRSWRLNIS 271 Query: 172 QTIYRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVTGIYTNNFDLS- 348 Q+ ++++QK+ +QE+ +P G +PR +VIL D+++ A+ G++ TGI D+S Sbjct: 272 QSSFQDWQKVRIQENSNEIPTGSMPRTLDVILRGDIVERAKAGDKCAFTGILIAVPDVSQ 331 Query: 349 -----------------------------------LNTKNGFPVFATVVEANYVSKK--- 414 L K F A +V+ + + K Sbjct: 332 LGIPGVKPEAYRDSRNFGGRDADGVTGLKSLGVRDLTYKLSF--LACMVQPDDANDKSGA 389 Query: 415 ------------QDLFSAYKLTDEDKAEIEKLSKDPRISERIVKSIAPSIYGHEDIKTAI 558 QD F L+ E+ ++ + I R+ S+APS+YGHE IK I Sbjct: 390 DVRGDGSQGIEEQDEF-LQSLSQEEIDDLRAMVHSDHIYSRLTNSLAPSVYGHEIIKKGI 448 Query: 559 ALAMFGGQEK 588 L + GG K Sbjct: 449 LLQLMGGVHK 458
>MCM7_XENLA (Q91876) DNA replication licensing factor MCM7 (CDC47 homolog)| (x.MCM7) Length = 720 Score = 81.3 bits (199), Expect = 2e-15 Identities = 60/212 (28%), Positives = 98/212 (46%), Gaps = 12/212 (5%) Frame = +1 Query: 1 GVVTRRXGVFPQLQQVKYDCSKCGTVLGPFFQNSYTEVRVGSCP--ECQ---SKGPFTVN 165 G+VTR V P + Y C +CG Q S T + + CP ECQ S G + Sbjct: 164 GIVTRVTEVKPMMVVATYTCDQCGAETYQPIQ-SPTFMPLIMCPSRECQTNRSGGRLYLQ 222 Query: 166 IEQTIYRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVTGIYTNNFDL 345 + + +Q+L +QE VP G +PR V + + A+PG+ + +TG++ Sbjct: 223 TRGSKFIKFQELKIQEHSDQVPVGNIPRCMSVYVRGENTRLAQPGDHVGITGVFLPMLRT 282 Query: 346 SLNTKNGFPVFATVVEANYVSKKQDLFSAYKLTDEDKAEIEKLSKDPR-------ISERI 504 + T +E + + K T++D+ E+LS++ E++ Sbjct: 283 GFRQVVQGLLSETYLECHRLVKMNK-------TEDDELGTEELSEEELRQITEEDFYEKL 335 Query: 505 VKSIAPSIYGHEDIKTAIALAMFGGQEKNVKG 600 SIAP IYGHED+K A+ L + GG + + +G Sbjct: 336 AASIAPEIYGHEDVKKALLLLLVGGVDNSPRG 367
>MCM6_CAEEL (P34647) DNA replication licensing factor mcm-6| Length = 810 Score = 80.9 bits (198), Expect = 3e-15 Identities = 50/241 (20%), Positives = 105/241 (43%), Gaps = 45/241 (18%) Frame = +1 Query: 1 GVVTRRXGVFPQLQQVKYDCSKCGTVLGPFFQN-SYTEVRVGSCPECQSKGPFTVNIEQT 177 G + R V P+L + + C CG Q YT+ + P+C ++ F++++ + Sbjct: 138 GQIVRTHPVHPELSRACFVCEDCGVTTRDVQQQFRYTQPTKCANPQCMNRTRFSLDVNSS 197 Query: 178 IYRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVTGIYTNNFDLSLNT 357 + ++QK+ +QE+ +P G +PR +VI+ ++++ +PG++ ++ G D++ + Sbjct: 198 TFVDFQKIRIQETQAELPRGSIPRTVDVIVRGEMVETVQPGDKCDIVGTLIVIPDIAQLS 257 Query: 358 KNGFPVFATVVEANYVSKKQDLFSAYK--------------------------------- 438 G + + K + + K Sbjct: 258 TPGLRAETSNQNRGRATDKSEGITGLKALGVRDLTYKMAFLACHIQQTESLVGGDASGAV 317 Query: 439 -----------LTDEDKAEIEKLSKDPRISERIVKSIAPSIYGHEDIKTAIALAMFGGQE 585 ++ ED+A ++K+S D +I + IV S+ P+IYG+ ++K + L + GG Sbjct: 318 EETDYLDLWSKMSTEDRATLKKMSDDKKIEKNIVDSLFPNIYGNHEVKLGVLLMLLGGVA 377 Query: 586 K 588 K Sbjct: 378 K 378
>MCM6_CAEBR (Q61J08) DNA replication licensing factor mcm-6| Length = 810 Score = 78.2 bits (191), Expect = 2e-14 Identities = 49/244 (20%), Positives = 106/244 (43%), Gaps = 45/244 (18%) Frame = +1 Query: 1 GVVTRRXGVFPQLQQVKYDCSKCGTVLGPFFQN-SYTEVRVGSCPECQSKGPFTVNIEQT 177 G + R V P+L + + C CG Q YT+ + P+C ++ F++++ + Sbjct: 138 GQIVRTHPVHPELSRACFVCEDCGVSTRDVQQQFRYTQPTKCANPQCMNRTRFSLDVNSS 197 Query: 178 IYRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVTGIYTNNFDLSLNT 357 + ++QK+ +QE+ +P G +PR +VI+ ++++ +PG++ ++ G D++ + Sbjct: 198 TFVDFQKIRIQETQAELPRGSIPRTVDVIVRGEMVETVQPGDKCDIVGTLIVIPDIAQLS 257 Query: 358 KNGFPVFATVVEANYVSKKQDLFSAYK--------------------------------- 438 G + + K + + K Sbjct: 258 TPGLRAETSNQNRGRATDKSEGITGLKALGVRDLTYKMAFLACHIQQTESLVGGDASGAM 317 Query: 439 -----------LTDEDKAEIEKLSKDPRISERIVKSIAPSIYGHEDIKTAIALAMFGGQE 585 ++ ED++ ++++S D +I + IV S+ P+IYG+ ++K + L + GG Sbjct: 318 EENDYLELWTKMSPEDRSVLKQMSDDKKIEKNIVDSLFPNIYGNHEVKLGVLLMLLGGVA 377 Query: 586 KNVK 597 K K Sbjct: 378 KKSK 381
>MCM6_DROME (Q9V461) DNA replication licensing factor Mcm6 (Minichromosome| maintenance 6 protein) (DmMCM6) Length = 817 Score = 77.4 bits (189), Expect = 3e-14 Identities = 59/243 (24%), Positives = 106/243 (43%), Gaps = 42/243 (17%) Frame = +1 Query: 1 GVVTRRXGVFPQLQQVKYDCSKCGTVLGPFFQN-SYTEVRVGSCPECQSKGPFTVNIEQT 177 G V R V P+L + C C T + Q +T + P C ++ F +++E++ Sbjct: 133 GQVVRTHPVHPELVSGVFMCLDCQTEIRNVEQQFKFTNPTICRNPVCSNRKRFMLDVEKS 192 Query: 178 IYRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVTGIYTNNFDLS--- 348 ++ ++QK+ +QE+ +P G +PR E+IL ++L++ + G+ + TG D+S Sbjct: 193 LFLDFQKIRIQETQAELPRGCIPRAVEIILRSELVETVQAGDRYDFTGTLIVVPDVSVLA 252 Query: 349 -------------------------------LNTKNGF---PVFATVVEANYVSKKQDLF 426 LN + F V AT Sbjct: 253 GVGTRAENSSRHKPGEGMDGVTGLKALGMRELNYRMAFLACSVQATTARFGGTDLPMSEV 312 Query: 427 SA----YKLTDEDKAEIEKLSKDPRISERIVKSIAPSIYGHEDIKTAIALAMFGGQEKNV 594 +A ++TD + +I ++SKD + + ++ S+ PSIYG++++K I L FGG K Sbjct: 313 TAEDMKKQMTDAEWHKIYEMSKDRNLYQNLISSLFPSIYGNDEVKRGILLQQFGGVAKTT 372 Query: 595 KGK 603 K Sbjct: 373 TEK 375
>CDC54_YEAST (P30665) Cell division control protein 54| Length = 933 Score = 77.4 bits (189), Expect = 3e-14 Identities = 55/223 (24%), Positives = 100/223 (44%), Gaps = 27/223 (12%) Frame = +1 Query: 1 GVVTRRXGVFPQLQQVKYDCSKCGTVLGPFFQNSYTEVRVGSCPECQSKGPFTVNI--EQ 174 G+V R V P ++ + C+ C + + C P ++++ + Sbjct: 330 GLVLRSTPVIPDMKVAFFKCNVCDHTMAVEIDRGVIQ-EPARCERIDCNEPNSMSLIHNR 388 Query: 175 TIYRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVTGIYTNNFDLSLN 354 + + Q + LQE+P VP G+ P + + ++L+D R G+ IEVTG + + + N Sbjct: 389 CSFADKQVIKLQETPDFVPDGQTPHSISLCVYDELVDSCRAGDRIEVTGTF-RSIPIRAN 447 Query: 355 T-----KNGFPVFATVVEANYVSKKQ--------------------DLFSAYKLTDEDKA 459 + K+ + + VV VS K+ ++ ++TD+D A Sbjct: 448 SRQRVLKSLYKTYVDVVHVKKVSDKRLDVDTSTIEQELMQNKVDHNEVEEVRQITDQDLA 507 Query: 460 EIEKLSKDPRISERIVKSIAPSIYGHEDIKTAIALAMFGGQEK 588 +I +++ + + +SIAPSIY ED+K I L +FGG K Sbjct: 508 KIREVAAREDLYSLLARSIAPSIYELEDVKKGILLQLFGGTNK 550
>MCM6_ANOGA (Q7Q0Q1) DNA replication licensing factor Mcm6| Length = 814 Score = 76.6 bits (187), Expect = 5e-14 Identities = 55/244 (22%), Positives = 108/244 (44%), Gaps = 43/244 (17%) Frame = +1 Query: 1 GVVTRRXGVFPQLQQVKYDCSKCGTVLGPFFQN-SYTEVRVGSCPECQSKGPFTVNIEQT 177 G V R V P+L + C C T + Q +T + P C ++ F + ++++ Sbjct: 133 GQVVRTHPVHPELVLGTFVCLDCQTEIRDVEQQFKFTNPTICRNPVCANRRRFMLEVDKS 192 Query: 178 IYRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVTGIYTNNFDL---- 345 ++ ++QK+ +QE+ +P G +PR EVIL ++++ + G+ + TG D+ Sbjct: 193 LFIDFQKVRIQETQAELPRGCIPRSVEVILRAEMVETVQAGDRYDFTGTLIVIPDVGALQ 252 Query: 346 -------------------------------SLNTKNGFPVFATVVEANY-------VSK 411 LN K F + V ++ +S+ Sbjct: 253 LPGAKAEIGSRHKQGDNAAEGVRGLKALGMRDLNYKMAFLACSVQVTSSRFGGTDMPMSE 312 Query: 412 KQDLFSAYKLTDEDKAEIEKLSKDPRISERIVKSIAPSIYGHEDIKTAIALAMFGGQEKN 591 ++T + ++ ++S+DPR+ + ++ S+ PSIYG++++K I L +FGG K Sbjct: 313 VTSQIMKDQMTPAEWNKVYEMSRDPRLYQNLINSLFPSIYGNDEVKRGILLMLFGGVAKT 372 Query: 592 VKGK 603 + K Sbjct: 373 TQEK 376
>MCM6_DROPS (Q29JI9) DNA replication licensing factor Mcm6 (Minichromosome| maintenance 6 protein) Length = 815 Score = 75.5 bits (184), Expect = 1e-13 Identities = 57/238 (23%), Positives = 105/238 (44%), Gaps = 42/238 (17%) Frame = +1 Query: 1 GVVTRRXGVFPQLQQVKYDCSKCGTVLGPFFQN-SYTEVRVGSCPECQSKGPFTVNIEQT 177 G V R V P+L + C C T + Q +T + P C ++ F +++E++ Sbjct: 133 GQVVRTHPVHPELVSGTFMCLDCQTEIRNVEQQFKFTNPTICRNPVCSNRRRFMLDVEKS 192 Query: 178 IYRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVTGIYTNNFDLS--- 348 ++ ++QK+ +QE+ +P G +PR E+IL ++L++ + G+ + TG D+S Sbjct: 193 LFLDFQKIRIQETQAELPRGCIPRAVEIILRSELVETVQAGDRYDFTGTLIVVPDVSVLA 252 Query: 349 -------------------------------LNTKNGF---PVFATVVEANYVSKKQDLF 426 LN + F V AT Sbjct: 253 MPGTRAESGSRHKPGEGMEGVTGLKALGMRELNYRMAFLACSVQATTARFGGTDLPMSEV 312 Query: 427 SA----YKLTDEDKAEIEKLSKDPRISERIVKSIAPSIYGHEDIKTAIALAMFGGQEK 588 +A ++TD + +I ++SKD + + ++ + PSIYG++++K I L +FGG K Sbjct: 313 TAEDMKKQMTDAEWHKIYEMSKDRNLYQNLITCLFPSIYGNDEVKRGILLQLFGGVAK 370
>MCM5_SCHPO (P41389) DNA replication licensing factor mcm5 (Minichromosome| maintenance protein 5) (Cell division control protein nda4) Length = 720 Score = 75.1 bits (183), Expect = 1e-13 Identities = 53/156 (33%), Positives = 85/156 (54%), Gaps = 10/156 (6%) Frame = +1 Query: 151 PFTVNIEQTIYRNYQKLTLQESPGIVPAGRLPRYKEVILLND---LIDCARPGEEIEVTG 321 PF ++ ++ + + Q L LQE+P +VP G LPR+ ILLN L + PG +TG Sbjct: 207 PFIIDHSKSTFIDQQVLKLQEAPDMVPVGELPRH---ILLNADRYLTNQITPGTRCVITG 263 Query: 322 IYTNNFDLSLNTKNGFPV---FATVV----EANYVSKKQDLFSAYKLTDEDKAEIEKLSK 480 I++ + S+ + + VV ++N SK LFS +E++ E ++S+ Sbjct: 264 IFSIFQNKSVKASGAVAIRNPYIRVVGIQMDSNDGSKSTPLFS-----EEEEEEFLEISR 318 Query: 481 DPRISERIVKSIAPSIYGHEDIKTAIALAMFGGQEK 588 P + + I SI+P+IYG+ DIK AIA +F G +K Sbjct: 319 TPNLYDIISNSISPAIYGNVDIKKAIACLLFSGSKK 354
>MCM6_YEAST (P53091) DNA replication licensing factor MCM6 (Minichromosome| maintenance protein 6) Length = 1017 Score = 72.4 bits (176), Expect = 1e-12 Identities = 34/109 (31%), Positives = 63/109 (57%), Gaps = 1/109 (0%) Frame = +1 Query: 1 GVVTRRXGVFPQLQQVKYDCSKCGTVLGPFFQN-SYTEVRVGSCPECQSKGPFTVNIEQT 177 G VTR V P+L + + C C ++ Q+ YTE P C+++ +T+N+ ++ Sbjct: 292 GTVTRTSEVRPELYKASFTCDMCRAIVDNVEQSFKYTEPTFCPNPSCENRAFWTLNVTRS 351 Query: 178 IYRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVTGI 324 + ++QK+ +QE+ +P G +PR +VIL D ++ A+PG+ + TG+ Sbjct: 352 RFLDWQKVRIQENANEIPTGSMPRTLDVILRGDSVERAKPGDRCKFTGV 400 Score = 49.7 bits (117), Expect = 7e-06 Identities = 28/88 (31%), Positives = 51/88 (57%), Gaps = 4/88 (4%) Frame = +1 Query: 340 DLSLNTKNGFPVFATVVEANYV----SKKQDLFSAYKLTDEDKAEIEKLSKDPRISERIV 507 D + N + A ++AN V + Q++F L+ ++ E++++ KD I +++V Sbjct: 472 DANSNNRETELQMAANLQANNVYQDNERDQEVF-LNSLSSDEINELKEMVKDEHIYDKLV 530 Query: 508 KSIAPSIYGHEDIKTAIALAMFGGQEKN 591 +SIAP+++GHE +K I L M GG K+ Sbjct: 531 RSIAPAVFGHEAVKKGILLQMLGGVHKS 558
>MCM5_HUMAN (P33992) DNA replication licensing factor MCM5 (CDC46 homolog)| (P1-CDC46) Length = 734 Score = 72.0 bits (175), Expect = 1e-12 Identities = 48/163 (29%), Positives = 79/163 (48%), Gaps = 8/163 (4%) Frame = +1 Query: 130 PECQSKGPFTVNIEQTIYRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEI 309 P+C P+ + ++ ++Q L LQE P VP G +PR+ ++ L D PG + Sbjct: 205 PKCPLD-PYFIMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCDRYLCDKVVPGNRV 263 Query: 310 EVTGIYTNNFDLSLNTKNGFPVFATVVEANYV--------SKKQDLFSAYKLTDEDKAEI 465 + GIY+ L T G + ++Y+ + A ++ +++ E Sbjct: 264 TIMGIYSIK-KFGLTTSRGRDRVGVGIRSSYIRVLGIQVDTDGSGRSFAGAVSPQEEEEF 322 Query: 466 EKLSKDPRISERIVKSIAPSIYGHEDIKTAIALAMFGGQEKNV 594 +L+ P + E I KSIAPSI+G D+K AIA +FGG K + Sbjct: 323 RRLAALPNVYEVISKSIAPSIFGGTDMKKAIACLLFGGSRKRL 365
>MCM5_MOUSE (P49718) DNA replication licensing factor MCM5 (CDC46 homolog)| (P1-CDC46) Length = 733 Score = 71.6 bits (174), Expect = 2e-12 Identities = 48/163 (29%), Positives = 79/163 (48%), Gaps = 8/163 (4%) Frame = +1 Query: 130 PECQSKGPFTVNIEQTIYRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEI 309 P+C P+ + ++ ++Q L LQE P VP G +PR+ ++ L D PG + Sbjct: 204 PKCPLD-PYFIMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCDRYLCDKVVPGNRV 262 Query: 310 EVTGIYTNNFDLSLNTKNGFPVFATVVEANYV--------SKKQDLFSAYKLTDEDKAEI 465 + GIY+ LN G + ++Y+ + A ++ +++ E Sbjct: 263 TIMGIYSIK-KFGLNPSKGRDRVGVGIRSSYIRVLGIQVDTDGSGRSFAGSVSPQEEEEF 321 Query: 466 EKLSKDPRISERIVKSIAPSIYGHEDIKTAIALAMFGGQEKNV 594 +L+ P I E I KSI+PSI+G D+K AIA +FGG K + Sbjct: 322 RRLAALPNIYELISKSISPSIFGGMDMKKAIACLLFGGSRKRL 364
>MCM5_YEAST (P29496) Minichromosome maintenance protein 5 (Cell division| control protein 46) Length = 775 Score = 71.2 bits (173), Expect = 2e-12 Identities = 49/164 (29%), Positives = 77/164 (46%), Gaps = 18/164 (10%) Frame = +1 Query: 151 PFTVNIEQTIYRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVTGIYT 330 P+ + E + + + Q L LQE P +VP G +PR + L + PG + + GIY+ Sbjct: 240 PYIIIHESSKFIDQQFLKLQEIPELVPVGEMPRNLTMTCDRYLTNKVIPGTRVTIVGIYS 299 Query: 331 NNFDLSLNTKNGF------------------PVFATVVEANYVSKKQDLFSAYKLTDEDK 456 N+KNG P + + V S T+E++ Sbjct: 300 -----IYNSKNGAGSGRSGGGNGGSGVAIRTPYIKILGIQSDVETSSIWNSVTMFTEEEE 354 Query: 457 AEIEKLSKDPRISERIVKSIAPSIYGHEDIKTAIALAMFGGQEK 588 E +LS++P++ E + SIAPSI+G+EDIK AI + GG +K Sbjct: 355 EEFLQLSRNPKLYEILTNSIAPSIFGNEDIKKAIVCLLMGGSKK 398
>MCM6_MOUSE (P97311) DNA replication licensing factor MCM6 (Mis5 homolog)| Length = 821 Score = 70.9 bits (172), Expect = 3e-12 Identities = 54/240 (22%), Positives = 106/240 (44%), Gaps = 44/240 (18%) Frame = +1 Query: 1 GVVTRRXGVFPQLQQVKYDCSKCGTVLGPFFQN-SYTEVRVGSCPECQSKGPFTVNIEQT 177 G V R V P+L + C C TV+ Q YT+ + P C ++ F ++ ++ Sbjct: 139 GQVVRTHPVHPELVSGTFLCLDCQTVIKDVEQQFKYTQPNICRNPVCANRKRFLLDTNKS 198 Query: 178 IYRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVTGIYTNNFDLS--- 348 + ++QK+ +QE+ +P G +PR EVIL + ++ A+ G+ + TG D+S Sbjct: 199 RFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQAGDRCDFTGALIVVPDVSKLS 258 Query: 349 -----------LNTKNGFPV---------------FATVVEANYVSKKQDLFSAYKLTDE 450 ++ +G+ + V A +V+ F +L DE Sbjct: 259 TPGARAETNSRVSGADGYETEGIRGLRALGVRDLSYRLVFLACHVAPTNPRFGGKELRDE 318 Query: 451 DKA--------------EIEKLSKDPRISERIVKSIAPSIYGHEDIKTAIALAMFGGQEK 588 ++ ++ ++S+D + + S+ P+I+G++++K + L +FGG K Sbjct: 319 EQTAESIKNQMTVKEWEKVFEMSQDKNLYHNLCTSLFPTIHGNDEVKRGVLLMLFGGVPK 378
>MCM6_HUMAN (Q14566) DNA replication licensing factor MCM6 (P105MCM)| Length = 821 Score = 69.3 bits (168), Expect = 8e-12 Identities = 54/240 (22%), Positives = 106/240 (44%), Gaps = 44/240 (18%) Frame = +1 Query: 1 GVVTRRXGVFPQLQQVKYDCSKCGTVLGPFFQN-SYTEVRVGSCPECQSKGPFTVNIEQT 177 G V R V P+L + C C TV+ Q YT+ + P C ++ F ++ ++ Sbjct: 139 GQVVRTHPVHPELVSGTFLCLDCQTVIRDVEQQFKYTQPNICRNPVCANRRRFLLDTNKS 198 Query: 178 IYRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVTGIYTNNFDLS--- 348 + ++QK+ +QE+ +P G +PR EVIL + ++ A+ G++ + TG D+S Sbjct: 199 RFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQAGDKCDFTGTLIVVPDVSKLS 258 Query: 349 -----------LNTKNGFPV---------------FATVVEANYVSKKQDLFSAYKLTDE 450 ++ +G+ + V A V+ F +L DE Sbjct: 259 TPGARAETNSRVSGVDGYETEGIRGLRALGVRDLSYRLVFLACCVAPTNPRFGGKELRDE 318 Query: 451 DKA--------------EIEKLSKDPRISERIVKSIAPSIYGHEDIKTAIALAMFGGQEK 588 ++ ++ ++S+D + + S+ P+I+G++++K + L +FGG K Sbjct: 319 EQTAESIKNQMTVKEWEKVFEMSQDKNLYHNLCTSLFPTIHGNDEVKRGVLLMLFGGVPK 378
>MCM6M_XENLA (Q5FWY4) Maternal DNA replication licensing factor mcm6 (Maternal| minichromosome maintenance protein 6) (mMCM6) (xMCM6) Length = 821 Score = 68.6 bits (166), Expect = 1e-11 Identities = 54/240 (22%), Positives = 101/240 (42%), Gaps = 44/240 (18%) Frame = +1 Query: 1 GVVTRRXGVFPQLQQVKYDCSKCGTVLGPFFQN-SYTEVRVGSCPECQSKGPFTVNIEQT 177 G V R V P+L + C C +++ Q YT+ + P C ++ FT++ ++ Sbjct: 141 GQVVRTHPVHPELVSGTFLCMDCQSIVKDVEQQFRYTQPTICKNPVCANRRRFTLDTNKS 200 Query: 178 IYRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVTGIYTNNFDLS--- 348 + ++QK+ +QE+ +P G +PR E+IL + ++ A G+ + TG D+S Sbjct: 201 RFVDFQKVRIQETQAELPRGAIPRSVEIILRAEAVESAMAGDRCDFTGTLIVVPDVSALA 260 Query: 349 ---LNTKNGFPV-----------------------FATVVEANYVSKKQDLFSAYKLTDE 450 + G V + A YV F L +E Sbjct: 261 AGDARMETGAKVTGGEGFNSEGVQGLKALGVRDLSYRLAFLACYVGATNPRFGGKDLREE 320 Query: 451 DKA--------------EIEKLSKDPRISERIVKSIAPSIYGHEDIKTAIALAMFGGQEK 588 D+ ++ ++S+D + + S+ P+I+G+++IK + L +FGG K Sbjct: 321 DQTAESIKNQMTVQEWEKVFEMSQDKNLYHNLCTSLFPTIHGNDEIKRGVLLMLFGGVPK 380
>MCM6M_XENTR (Q28CM3) Maternal DNA replication licensing factor mcm6 (Maternal| minichromosome maintenance protein 6) (mMCM6) Length = 821 Score = 67.4 bits (163), Expect = 3e-11 Identities = 54/240 (22%), Positives = 101/240 (42%), Gaps = 44/240 (18%) Frame = +1 Query: 1 GVVTRRXGVFPQLQQVKYDCSKCGTVLGPFFQN-SYTEVRVGSCPECQSKGPFTVNIEQT 177 G V R V P+L + C C +V+ Q YT+ + P C ++ FT++ ++ Sbjct: 140 GQVVRTHPVHPELVSGTFLCMDCQSVVKDVEQQFRYTQPTICKNPVCANRRRFTLDTNKS 199 Query: 178 IYRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVTGIYTNNFDLS--- 348 + ++QK+ +QE+ +P G +PR E+IL + ++ A G+ + TG D+S Sbjct: 200 RFVDFQKVRIQETQAELPRGAIPRSVEIILRAEAVETAMAGDRCDFTGTLIVVPDISALA 259 Query: 349 ---LNTKNGFPV-----------------------FATVVEANYVSKKQDLFSAYKLTDE 450 + G V + A +V F L +E Sbjct: 260 AGDARMETGAKVTGGEGFNSEGVQGLKALGVRDLSYRLAFLACHVGATNPRFGGKDLREE 319 Query: 451 DKA--------------EIEKLSKDPRISERIVKSIAPSIYGHEDIKTAIALAMFGGQEK 588 D+ ++ ++S+D + + S+ P+I+G+++IK + L +FGG K Sbjct: 320 DQTAESIKNQMTVQEWEKVFEMSQDKNLYHNLCTSLFPTIHGNDEIKRGVLLMLFGGVPK 379
>MC6ZB_XENLA (Q7ZY18) Zygotic DNA replication licensing factor mcm6-B (Zygotic| minichromosome maintenance protein 6-B) (zMCM6-B) (zMCM6b) Length = 825 Score = 67.4 bits (163), Expect = 3e-11 Identities = 53/241 (21%), Positives = 102/241 (42%), Gaps = 44/241 (18%) Frame = +1 Query: 1 GVVTRRXGVFPQLQQVKYDCSKCGTVLGPFFQN-SYTEVRVGSCPECQSKGPFTVNIEQT 177 G V R V P+L + C C T++ Q YT+ + P C ++ F ++ ++ Sbjct: 140 GQVVRTHPVHPELVSGTFLCLDCQTLVRDVEQQFKYTQPSICRNPVCANRKRFMLDTNKS 199 Query: 178 IYRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVTGIYTNNFDLS--- 348 + ++QK+ +QE+ +P G +PR EVIL + ++ + G+ + TG D+S Sbjct: 200 RFVDFQKVRIQETQAELPRGSIPRSVEVILRAEAVESCQAGDRCDFTGSLIVVPDISQLS 259 Query: 349 -----------LNTKNGFPV---------------FATVVEANYVSKKQDLFSAYKLTDE 450 + + G+ + V A YV F L +E Sbjct: 260 TPGVRAETSSRVGGREGYEAEGVQGLRALGVRDLSYKLVFLACYVCPTNPRFGGKDLHEE 319 Query: 451 DKA--------------EIEKLSKDPRISERIVKSIAPSIYGHEDIKTAIALAMFGGQEK 588 D ++ ++S+D + + S+ P+++G++++K I L +FGG K Sbjct: 320 DMTAESIKNQMSVKEWEKVFEMSQDKNLYHNLCTSLFPTVHGNDEVKRGILLMLFGGVPK 379 Query: 589 N 591 + Sbjct: 380 S 380
>MC6ZA_XENLA (Q498J7) Zygotic DNA replication licensing factor mcm6-A (Zygotic| minichromosome maintenance protein 6-A) (zMCM6-A) (zMCM6a) Length = 823 Score = 66.6 bits (161), Expect = 5e-11 Identities = 52/239 (21%), Positives = 102/239 (42%), Gaps = 44/239 (18%) Frame = +1 Query: 7 VTRRXGVFPQLQQVKYDCSKCGTVLGPFFQN-SYTEVRVGSCPECQSKGPFTVNIEQTIY 183 V R V P+L + C C T++ Q YT+ + P C ++ F ++ ++ + Sbjct: 142 VVRTHPVHPELVSGTFLCLDCQTLVRDVEQQFKYTQPSICRNPVCANRRRFMLDTNKSRF 201 Query: 184 RNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVTGIYTNNFDLS----- 348 ++QK+ +QE+ +P G +PR EVIL + ++ + G+ + TG D+S Sbjct: 202 VDFQKVRIQETQAELPRGSIPRSVEVILRAEAVESCQAGDRCDFTGSLIVVPDISQLSTP 261 Query: 349 ---------LNTKNGFPV---------------FATVVEANYVSKKQDLFSAYKLTDEDK 456 + + G+ + V A YV F +L +ED Sbjct: 262 GVRAETSSRVGGREGYEAEGVQGLRALGVRDLSYKLVFLACYVCPTNPRFGGKELHEEDM 321 Query: 457 A--------------EIEKLSKDPRISERIVKSIAPSIYGHEDIKTAIALAMFGGQEKN 591 ++ ++S+D + + S+ P+++G++++K I L +FGG K+ Sbjct: 322 TAESIKNQMSVKEWEKVFEMSQDKNLYHNLCTSLFPTVHGNDEVKRGILLMLFGGVPKS 380
>MCM6Z_XENTR (Q6P1V8) Zygotic DNA replication licensing factor mcm6 (Zygotic| minichromosome maintenance protein 6) (zMCM6) Length = 823 Score = 65.9 bits (159), Expect = 9e-11 Identities = 53/240 (22%), Positives = 98/240 (40%), Gaps = 44/240 (18%) Frame = +1 Query: 1 GVVTRRXGVFPQLQQVKYDCSKCGTVLGPFFQN-SYTEVRVGSCPECQSKGPFTVNIEQT 177 G V R V P+L + C C T++ Q YT+ + P C ++ F ++ ++ Sbjct: 140 GQVVRTHPVHPELVSGTFLCLDCQTLVRDVEQQFKYTQPSICRNPVCANRRRFMLDTNKS 199 Query: 178 IYRNYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVTGIYTNNFDLSLNT 357 + ++QK+ +QE+ +P G +PR EVIL + ++ + G+ + TG D+S Sbjct: 200 RFVDFQKVRIQETQAELPRGSIPRSVEVILRAEAVESCQAGDRCDFTGSLIVVPDISQLA 259 Query: 358 KNGFPV-----------------------------FATVVEANYVSKKQDLFSAYKLTDE 450 G + V A YV F L +E Sbjct: 260 TPGVRAETSARVGGTEGYQAEGVQGLRALGVRDLSYKLVFLACYVCPTNPRFGGKDLHEE 319 Query: 451 DKA--------------EIEKLSKDPRISERIVKSIAPSIYGHEDIKTAIALAMFGGQEK 588 D ++ ++S+D + + S+ P+++G++++K I L +FGG K Sbjct: 320 DMTAESIKNQMSVKEWEKVFEMSQDKNLYHNLCTSLFPTVHGNDEVKRGILLMLFGGVPK 379
>MCM5_CAEEL (Q21902) DNA replication licensing factor mcm-5| Length = 759 Score = 65.5 bits (158), Expect = 1e-10 Identities = 46/146 (31%), Positives = 69/146 (47%), Gaps = 10/146 (6%) Frame = +1 Query: 187 NYQKLTLQESPGIVPAGRLPRYKEVILLNDLIDCARPGEEIEVTGIYTNNFDLSLNTKNG 366 +YQ L LQE+P VP G +PR+ ++ L D PG + + G+Y+ L K G Sbjct: 224 DYQTLKLQENPEDVPHGEMPRHLQLFTERYLTDKVVPGNRVTIVGVYSIK---KLIQKKG 280 Query: 367 FPVFATVVEANYV----------SKKQDLFSAYKLTDEDKAEIEKLSKDPRISERIVKSI 516 + Y+ + F+ + T E++ + L++ E I KSI Sbjct: 281 GDKSLQGIRTPYLRVLGIHMETSGPGRTNFTTF--TPEEERMFKTLAQRKDAYELIAKSI 338 Query: 517 APSIYGHEDIKTAIALAMFGGQEKNV 594 APSIYG DIK +IA +FGG K + Sbjct: 339 APSIYGSADIKKSIACLLFGGARKKL 364
>MCMR_DROME (Q9VF30) DNA replication licensing factor REC (Protein mini| chromosome maintenance-related) (Protein recombination-defective) Length = 885 Score = 53.5 bits (127), Expect = 5e-07 Identities = 36/118 (30%), Positives = 58/118 (49%), Gaps = 4/118 (3%) Frame = +1 Query: 241 LPRYKEVILLNDLIDCARPGEEIEVTGIYT----NNFDLSLNTKNGFPVFATVVEANYVS 408 +P +V L +DL+D R G+E+ VTGI + + +T N + V S Sbjct: 348 MPAEMDVELRHDLVDAVRVGQEVVVTGILKLQELGDDTTTGDTSNQMQPYLKAVSIRDAS 407 Query: 409 KKQDLFSAYKLTDEDKAEIEKLSKDPRISERIVKSIAPSIYGHEDIKTAIALAMFGGQ 582 + FS + D I ++ +P + +V+SIAP +YGHE K A L++ GG+ Sbjct: 408 SIKREFS-----ERDLEAIVMINAEPNSFKLLVQSIAPEVYGHELPKAACLLSLLGGK 460
>Y1489_METJA (Q58884) Hypothetical MCM-type protein MJ1489| Length = 682 Score = 48.9 bits (115), Expect = 1e-05 Identities = 47/200 (23%), Positives = 87/200 (43%), Gaps = 4/200 (2%) Frame = +1 Query: 1 GVVTRRXGVFPQLQQVKYDCSKCGTVLGPFFQNSYTEVRVGSCPECQSKGPFTVNIEQTI 180 G++ + P L++ Y C KCG + T+ C EC ++ + ++I Sbjct: 132 GIIVMASKIRPMLKKAYYICPKCGREVVREIDILNTDSEKAVC-ECGAE--LNLIEHKSI 188 Query: 181 YRNYQKLTLQESPGIVP-AGRLPRYKEVILLNDLIDCARPG---EEIEVTGIYTNNFDLS 348 Y ++Q++ +Q+ ++ P+Y V L N PG +++TGI + Sbjct: 189 YTDFQEIKVQQPLDLMENPEEPPKYITVFLENS------PGIYAGRVKITGI-----PIK 237 Query: 349 LNTKNGFPVFATVVEANYVSKKQDLFSAYKLTDEDKAEIEKLSKDPRISERIVKSIAPSI 528 + P++ V+A + + D KLT+ D I+K++K + + + P I Sbjct: 238 VKKSKKLPIYDIHVKALHC-EVLDGEVKIKLTNSDIENIKKIAKRKDVVNILADRLIPEI 296 Query: 529 YGHEDIKTAIALAMFGGQEK 588 GH IK A+ L G +K Sbjct: 297 KGHSAIKKAVLLQQIKGVKK 316
>MCM6_RAT (Q62724) DNA replication licensing factor MCM6 (Intestinal DNA| replication protein) (Fragment) Length = 507 Score = 35.8 bits (81), Expect = 0.10 Identities = 13/51 (25%), Positives = 33/51 (64%) Frame = +1 Query: 436 KLTDEDKAEIEKLSKDPRISERIVKSIAPSIYGHEDIKTAIALAMFGGQEK 588 ++T ++ ++ ++S+D + + S+ P+I+G++++K + L +FGG K Sbjct: 14 QMTVKEWEKVFEMSQDQNLYHNLCTSLFPTIHGNDEVKRGVLLMLFGGVPK 64
>RECX_STRA5 (P59210) Regulatory protein recX| Length = 258 Score = 33.1 bits (74), Expect = 0.65 Identities = 21/74 (28%), Positives = 38/74 (51%), Gaps = 3/74 (4%) Frame = +1 Query: 346 SLNTKN-GFPVFATVVEANYVSKKQDLFS--AYKLTDEDKAEIEKLSKDPRISERIVKSI 516 SL TK + + TV++ + K Q+L YK D+ ++ K + +RI+ ++ Sbjct: 181 SLTTKGFDYQIVHTVIQNLEIEKDQELEEDLIYKELDKQYQKLSKKHDQYELKQRIINAL 240 Query: 517 APSIYGHEDIKTAI 558 Y +EDIK+A+ Sbjct: 241 MRKGYQYEDIKSAL 254
>POLG_HRV1B (P12916) Genome polyprotein [Contains: Coat protein VP4 (P1A); Coat| protein VP2 (P1B); Coat protein VP3 (P1C); Coat protein VP1 (P1D); Picornain 2A (EC 3.4.22.29) (Core protein P2A); Core protein P2B; Core protein P2C; Core protein P3A; Genome Length = 2156 Score = 32.7 bits (73), Expect = 0.85 Identities = 20/75 (26%), Positives = 36/75 (48%), Gaps = 1/75 (1%) Frame = +1 Query: 289 ARPGEEIEVTGIYTNNFD-LSLNTKNGFPVFATVVEANYVSKKQDLFSAYKLTDEDKAEI 465 A PG E++V GI+T D L ++G + TV++ + K +D+ T++D E Sbjct: 1554 ADPGREVQVNGIHTKVLDSYDLYNRDGVKLEITVIQLDRNEKFRDIRKYIPETEDDYPEC 1613 Query: 466 EKLSKDPRISERIVK 510 ++ I+K Sbjct: 1614 NLALSANQVEPTIIK 1628
>RECX_STRA3 (P59209) Regulatory protein recX| Length = 258 Score = 32.3 bits (72), Expect = 1.1 Identities = 21/74 (28%), Positives = 38/74 (51%), Gaps = 3/74 (4%) Frame = +1 Query: 346 SLNTKN-GFPVFATVVEANYVSKKQDLFS--AYKLTDEDKAEIEKLSKDPRISERIVKSI 516 SL TK + + TV++ + K Q+L YK D+ ++ K + +RI+ ++ Sbjct: 181 SLTTKGFDYQIAHTVIQNLEIEKDQELEEDLIYKELDKQYQKLSKKYDQYELKQRIINAL 240 Query: 517 APSIYGHEDIKTAI 558 Y +EDIK+A+ Sbjct: 241 MRKGYQYEDIKSAL 254
>SF3B2_HUMAN (Q13435) Splicing factor 3B subunit 2 (Spliceosome-associated| protein 145) (SAP 145) (SF3b150) (Pre-mRNA splicing factor SF3b 145 kDa subunit) Length = 872 Score = 32.3 bits (72), Expect = 1.1 Identities = 19/53 (35%), Positives = 31/53 (58%) Frame = +1 Query: 385 VVEANYVSKKQDLFSAYKLTDEDKAEIEKLSKDPRISERIVKSIAPSIYGHED 543 + E N++ K+ +F A+KLTD+ K E E K+P +++ S AP G E+ Sbjct: 355 IYEPNFIFFKR-IFEAFKLTDDVKKEKE---KEPEKLDKLENSAAPKKKGFEE 403
>RL9_CLOAB (Q97CX9) 50S ribosomal protein L9| Length = 147 Score = 31.6 bits (70), Expect = 1.9 Identities = 26/79 (32%), Positives = 36/79 (45%), Gaps = 5/79 (6%) Frame = +1 Query: 256 EVILLNDLIDCARPGEEIEVTGIYTNNF----DLSLNTKN-GFPVFATVVEANYVSKKQD 420 +VILL D+ + GE I V+ Y NF L+ N V +A K Q+ Sbjct: 2 KVILLKDIKSVGKKGEVINVSDGYARNFLFPRKLAEEANNSNMRVLNLKKDAERKQKLQE 61 Query: 421 LFSAYKLTDEDKAEIEKLS 477 A KL +E K ++ KLS Sbjct: 62 TEEAQKLANELKGKVLKLS 80
>YQE4_CAEEL (Q17529) Hypothetical protein B0564.4 in chromosome IV| Length = 523 Score = 31.6 bits (70), Expect = 1.9 Identities = 14/33 (42%), Positives = 23/33 (69%), Gaps = 1/33 (3%) Frame = +1 Query: 340 DLSLNTKNGFPVFATVVEANYVSKKQ-DLFSAY 435 D+S+ T+ FP TVV A ++SK + DL+++Y Sbjct: 142 DVSMRTRRRFPTMETVVAAGFMSKDELDLYNSY 174
>MURB_CORJK (Q4JSV7) UDP-N-acetylenolpyruvoylglucosamine reductase (EC| 1.1.1.158) (UDP-N-acetylmuramate dehydrogenase) Length = 434 Score = 30.8 bits (68), Expect = 3.2 Identities = 13/30 (43%), Positives = 20/30 (66%) Frame = -2 Query: 311 SISSPGRAQSIRSFRSITSLYLGSLPAGTI 222 S+S PG + RSF +T+L +G+ PAG + Sbjct: 30 SVSIPGTRVTSRSFAEMTTLRIGAAPAGVV 59
>DHAR_ECOLI (P76016) PTS-dependent dihydroxyacetone kinase operon regulatory| protein Length = 639 Score = 29.3 bits (64), Expect = 9.4 Identities = 21/66 (31%), Positives = 34/66 (51%), Gaps = 1/66 (1%) Frame = +1 Query: 277 LIDCARPGEEIEVTGIYTNNFDLSLNTKNGFPVFATVVEANYVSKKQDLFSAYKL-TDED 453 L+ CA PG + E+ + N L+L++ NG + + E + + D SA +L T Sbjct: 531 LVSCAWPGNDFELYSVIEN---LALSSDNGRIRVSDLPEHLFTEQATDDVSATRLSTSLS 587 Query: 454 KAEIEK 471 AE+EK Sbjct: 588 FAEVEK 593
>POLG_HRV16 (Q82122) Genome polyprotein [Contains: Coat protein VP4 (P1A); Coat| protein VP2 (P1B); Coat protein VP3 (P1C); Coat protein VP1 (P1D); Picornain 2A (EC 3.4.22.29) (Core protein P2A); Core protein P2B; Core protein P2C; Core protein P3A; Genome Length = 2152 Score = 29.3 bits (64), Expect = 9.4 Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 1/59 (1%) Frame = +1 Query: 289 ARPGEEIEVTGIYTNNFD-LSLNTKNGFPVFATVVEANYVSKKQDLFSAYKLTDEDKAE 462 A PG EI+V GI+T D L K G + TV++ + K +D+ +++D E Sbjct: 1550 ADPGSEIQVNGIHTKVLDSYDLFNKEGVKLEITVLKLDRNEKFRDIRKYIPESEDDYPE 1608
>YQE3_CAEEL (Q17528) Hypothetical protein B0564.3 in chromosome IV| Length = 450 Score = 29.3 bits (64), Expect = 9.4 Identities = 12/33 (36%), Positives = 23/33 (69%), Gaps = 1/33 (3%) Frame = +1 Query: 340 DLSLNTKNGFPVFATVVEANYVSKKQ-DLFSAY 435 D+S+ T+ FP TVV A +++K + +L+++Y Sbjct: 142 DMSMRTRRRFPTMETVVAAGFMNKHELELYNSY 174
>UNG_MYCPU (Q98PV4) Uracil-DNA glycosylase (EC 3.2.2.-) (UDG)| Length = 221 Score = 29.3 bits (64), Expect = 9.4 Identities = 12/37 (32%), Positives = 22/37 (59%) Frame = +1 Query: 409 KKQDLFSAYKLTDEDKAEIEKLSKDPRISERIVKSIA 519 KK+D+F A+ L D + ++ + +DP I+E +A Sbjct: 40 KKEDIFKAFDLVDFNNLKVVIIGQDPYINENQAHGLA 76
>RGS16_MOUSE (P97428) Regulator of G-protein signaling 16 (RGS16) (Retinally| abundant regulator of G-protein signaling) (RGS-R) (A28-RGS14P) Length = 201 Score = 29.3 bits (64), Expect = 9.4 Identities = 15/66 (22%), Positives = 33/66 (50%) Frame = +1 Query: 325 YTNNFDLSLNTKNGFPVFATVVEANYVSKKQDLFSAYKLTDEDKAEIEKLSKDPRISERI 504 + +FDL LN+KNG F ++ + + + + A + + ++ + S+ I + Sbjct: 61 WRESFDLLLNSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHHIFDEY 120 Query: 505 VKSIAP 522 ++S AP Sbjct: 121 IRSEAP 126
>RENT2_HUMAN (Q9HAU5) Regulator of nonsense transcripts 2 (Nonsense mRNA| reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2) Length = 1272 Score = 29.3 bits (64), Expect = 9.4 Identities = 10/25 (40%), Positives = 16/25 (64%) Frame = +3 Query: 498 KDCQINCAIHLWS*RYQDCHCTSNV 572 KD I C I++W+ +Y HC +N+ Sbjct: 806 KDYVICCMINIWNVKYNSIHCVANL 830 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.317 0.137 0.395 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 96,040,780 Number of Sequences: 219361 Number of extensions: 2123962 Number of successful extensions: 6401 Number of sequences better than 10.0: 65 Number of HSP's better than 10.0 without gapping: 6162 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6353 length of database: 80,573,946 effective HSP length: 107 effective length of database: 57,102,319 effective search space used: 5424720305 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits)
